BLASTP 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= BGIBMGA000894-TA|BGIBMGA000894-PA|IPR000308|14-3-3 protein, IPR010989|t-snare, IPR009054|DNA topoisomerases I, dispensable insert, eukaryotic-type, IPR009053|Prefoldin (1630 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_UPI0000D55C9F Cluster: PREDICTED: similar to Golgin sub... 251 1e-64 UniRef50_Q171W5 Cluster: Lava lamp protein; n=2; Culicidae|Rep: ... 236 3e-60 UniRef50_A2DLG0 Cluster: Viral A-type inclusion protein, putativ... 234 2e-59 UniRef50_A2DGN0 Cluster: Viral A-type inclusion protein, putativ... 232 7e-59 UniRef50_UPI000049A29E Cluster: Viral A-type inclusion protein r... 214 2e-53 UniRef50_A2FD36 Cluster: Viral A-type inclusion protein, putativ... 210 2e-52 UniRef50_A2E8Z5 Cluster: Viral A-type inclusion protein, putativ... 209 6e-52 UniRef50_Q24HK7 Cluster: Viral A-type inclusion protein repeat c... 208 1e-51 UniRef50_A2DD37 Cluster: Viral A-type inclusion protein, putativ... 206 5e-51 UniRef50_A2F531 Cluster: Viral A-type inclusion protein, putativ... 205 7e-51 UniRef50_A2EMR6 Cluster: Viral A-type inclusion protein, putativ... 204 2e-50 UniRef50_A0CPG2 Cluster: Chromosome undetermined scaffold_23, wh... 200 3e-49 UniRef50_UPI00015B5D72 Cluster: PREDICTED: similar to viral A-ty... 197 2e-48 UniRef50_A2EYA1 Cluster: Viral A-type inclusion protein, putativ... 197 2e-48 UniRef50_A7TQ63 Cluster: Putative uncharacterized protein; n=1; ... 197 2e-48 UniRef50_A2FSZ8 Cluster: Viral A-type inclusion protein, putativ... 196 3e-48 UniRef50_A2EN31 Cluster: Viral A-type inclusion protein, putativ... 196 3e-48 UniRef50_A2DDX5 Cluster: Viral A-type inclusion protein, putativ... 196 3e-48 UniRef50_Q23DH8 Cluster: DNA-directed RNA polymerase, omega subu... 196 4e-48 UniRef50_Q54G05 Cluster: Putative uncharacterized protein; n=1; ... 195 1e-47 UniRef50_A2DDP2 Cluster: Viral A-type inclusion protein, putativ... 194 2e-47 UniRef50_UPI0000DB6B83 Cluster: PREDICTED: similar to lava lamp ... 193 3e-47 UniRef50_A0BMM9 Cluster: Chromosome undetermined scaffold_117, w... 192 9e-47 UniRef50_A2E8H6 Cluster: Viral A-type inclusion protein, putativ... 188 1e-45 UniRef50_Q234R7 Cluster: Viral A-type inclusion protein repeat c... 188 1e-45 UniRef50_A2EZ87 Cluster: Viral A-type inclusion protein, putativ... 187 3e-45 UniRef50_UPI00006CDA45 Cluster: hypothetical protein TTHERM_0040... 186 3e-45 UniRef50_A2DKE3 Cluster: Viral A-type inclusion protein, putativ... 186 3e-45 UniRef50_Q22AT3 Cluster: Viral A-type inclusion protein repeat c... 186 6e-45 UniRef50_UPI0000D8E0D3 Cluster: UPI0000D8E0D3 related cluster; n... 185 1e-44 UniRef50_UPI00006CB2DA Cluster: Viral A-type inclusion protein r... 184 1e-44 UniRef50_UPI0000D8E0D4 Cluster: UPI0000D8E0D4 related cluster; n... 184 1e-44 UniRef50_A2FQ07 Cluster: Viral A-type inclusion protein, putativ... 184 2e-44 UniRef50_UPI00006CE95F Cluster: Viral A-type inclusion protein r... 181 1e-43 UniRef50_Q22RF4 Cluster: Viral A-type inclusion protein repeat c... 181 1e-43 UniRef50_A2DA80 Cluster: Viral A-type inclusion protein, putativ... 180 4e-43 UniRef50_A2FQ08 Cluster: Viral A-type inclusion protein, putativ... 179 7e-43 UniRef50_A2DKP8 Cluster: Viral A-type inclusion protein, putativ... 178 9e-43 UniRef50_A2ETW9 Cluster: Viral A-type inclusion protein, putativ... 177 2e-42 UniRef50_Q237L2 Cluster: Kinesin motor domain containing protein... 177 3e-42 UniRef50_A2EVM3 Cluster: Viral A-type inclusion protein, putativ... 175 6e-42 UniRef50_A2ERL6 Cluster: Viral A-type inclusion protein, putativ... 175 8e-42 UniRef50_Q23QC3 Cluster: Viral A-type inclusion protein repeat c... 175 1e-41 UniRef50_A2EZE6 Cluster: Viral A-type inclusion protein, putativ... 175 1e-41 UniRef50_A2FKT9 Cluster: Viral A-type inclusion protein, putativ... 174 1e-41 UniRef50_UPI00006CF26E Cluster: Viral A-type inclusion protein r... 172 6e-41 UniRef50_UPI00006CD2DD Cluster: Viral A-type inclusion protein r... 172 6e-41 UniRef50_A2FX23 Cluster: Formin Homology 2 Domain containing pro... 172 6e-41 UniRef50_A0CWJ6 Cluster: Chromosome undetermined scaffold_3, who... 172 6e-41 UniRef50_UPI00015A55AB Cluster: UPI00015A55AB related cluster; n... 172 8e-41 UniRef50_UPI00006CD140 Cluster: Viral A-type inclusion protein r... 170 2e-40 UniRef50_A2FKU0 Cluster: Viral A-type inclusion protein, putativ... 170 2e-40 UniRef50_UPI00006CD895 Cluster: hypothetical protein TTHERM_0052... 170 3e-40 UniRef50_A0CKK3 Cluster: Chromosome undetermined scaffold_2, who... 170 3e-40 UniRef50_A2FK27 Cluster: Viral A-type inclusion protein, putativ... 169 4e-40 UniRef50_A2F3I9 Cluster: Viral A-type inclusion protein, putativ... 169 4e-40 UniRef50_UPI00006CB352 Cluster: Viral A-type inclusion protein r... 169 5e-40 UniRef50_A2EJ43 Cluster: Viral A-type inclusion protein, putativ... 167 2e-39 UniRef50_A0DJQ4 Cluster: Chromosome undetermined scaffold_53, wh... 166 4e-39 UniRef50_A0BIQ2 Cluster: Chromosome undetermined scaffold_11, wh... 166 5e-39 UniRef50_A0DXX1 Cluster: Chromosome undetermined scaffold_69, wh... 165 7e-39 UniRef50_UPI00006CA483 Cluster: hypothetical protein TTHERM_0049... 165 1e-38 UniRef50_Q4LE75 Cluster: CENPE variant protein; n=9; Euteleostom... 165 1e-38 UniRef50_Q231C5 Cluster: Putative uncharacterized protein; n=1; ... 162 6e-38 UniRef50_Q6FWE0 Cluster: Candida glabrata strain CBS138 chromoso... 162 6e-38 UniRef50_A0CWT0 Cluster: Chromosome undetermined scaffold_3, who... 161 1e-37 UniRef50_A0CZI7 Cluster: Chromosome undetermined scaffold_32, wh... 160 3e-37 UniRef50_Q59K46 Cluster: Likely vesicular transport factor Uso1p... 160 3e-37 UniRef50_A0DBC2 Cluster: Chromosome undetermined scaffold_44, wh... 160 3e-37 UniRef50_A0DWU7 Cluster: Chromosome undetermined scaffold_67, wh... 159 4e-37 UniRef50_UPI0000F1EC3A Cluster: PREDICTED: hypothetical protein;... 158 1e-36 UniRef50_Q9FJ35 Cluster: Myosin heavy chain-like protein; n=2; A... 158 1e-36 UniRef50_A2EUG5 Cluster: Putative uncharacterized protein; n=3; ... 158 1e-36 UniRef50_A2DNX6 Cluster: Viral A-type inclusion protein, putativ... 158 1e-36 UniRef50_A0C3N5 Cluster: Chromosome undetermined scaffold_147, w... 158 1e-36 UniRef50_A2EPG1 Cluster: Viral A-type inclusion protein, putativ... 157 2e-36 UniRef50_UPI00006CC2B2 Cluster: hypothetical protein TTHERM_0066... 157 2e-36 UniRef50_A2F8N3 Cluster: Viral A-type inclusion protein, putativ... 157 2e-36 UniRef50_A0EHN8 Cluster: Chromosome undetermined scaffold_97, wh... 157 2e-36 UniRef50_Q02224 Cluster: Centromeric protein E; n=8; Eutheria|Re... 157 2e-36 UniRef50_Q23D13 Cluster: Viral A-type inclusion protein repeat c... 157 3e-36 UniRef50_UPI000065DFDD Cluster: Homolog of Homo sapiens "Centrom... 155 7e-36 UniRef50_Q22SA1 Cluster: Putative uncharacterized protein; n=1; ... 153 3e-35 UniRef50_A0DZ20 Cluster: Chromosome undetermined scaffold_7, who... 153 4e-35 UniRef50_A0CWC7 Cluster: Chromosome undetermined scaffold_3, who... 153 4e-35 UniRef50_A0DR95 Cluster: Chromosome undetermined scaffold_60, wh... 153 5e-35 UniRef50_Q6C359 Cluster: Similar to DEHA0C09658g Debaryomyces ha... 153 5e-35 UniRef50_UPI0000F2140F Cluster: PREDICTED: similar to nuclear mi... 152 7e-35 UniRef50_UPI0000E7FDD2 Cluster: PREDICTED: similar to trans-Golg... 152 9e-35 UniRef50_A2FU34 Cluster: Putative uncharacterized protein; n=1; ... 151 1e-34 UniRef50_A0BRG1 Cluster: Chromosome undetermined scaffold_122, w... 150 4e-34 UniRef50_Q4RQ56 Cluster: Chromosome 17 SCAF15006, whole genome s... 149 5e-34 UniRef50_UPI0000498399 Cluster: Viral A-type inclusion protein r... 149 6e-34 UniRef50_A2DGH5 Cluster: Viral A-type inclusion protein, putativ... 149 8e-34 UniRef50_UPI0000D565C6 Cluster: PREDICTED: similar to CG3493-PA;... 148 1e-33 UniRef50_UPI00015A607A Cluster: UPI00015A607A related cluster; n... 148 1e-33 UniRef50_O76329 Cluster: Interaptin; n=2; Dictyostelium discoide... 147 2e-33 UniRef50_A0DDW1 Cluster: Chromosome undetermined scaffold_47, wh... 147 2e-33 UniRef50_Q22RB5 Cluster: Putative uncharacterized protein; n=1; ... 147 3e-33 UniRef50_Q13439 Cluster: Golgin subfamily A member 4; n=34; Tetr... 147 3e-33 UniRef50_Q25893 Cluster: Liver stage antigen; n=41; Plasmodium f... 146 4e-33 UniRef50_Q2NJC3 Cluster: Putative uncharacterized protein; n=1; ... 145 8e-33 UniRef50_A0DBE4 Cluster: Chromosome undetermined scaffold_44, wh... 145 8e-33 UniRef50_Q6BUQ9 Cluster: Similar to sp|P25386 Saccharomyces cere... 145 8e-33 UniRef50_UPI000150A61D Cluster: hypothetical protein TTHERM_0037... 144 1e-32 UniRef50_Q1FIV0 Cluster: Putative uncharacterized protein; n=1; ... 144 2e-32 UniRef50_A2FVB6 Cluster: Putative uncharacterized protein; n=2; ... 144 2e-32 UniRef50_A0BUU6 Cluster: Chromosome undetermined scaffold_13, wh... 144 2e-32 UniRef50_UPI0000499259 Cluster: hypothetical protein 388.t00006;... 144 2e-32 UniRef50_Q10411 Cluster: Sporulation-specific protein 15; n=1; S... 144 2e-32 UniRef50_A0CQM3 Cluster: Chromosome undetermined scaffold_24, wh... 143 3e-32 UniRef50_Q86KX8 Cluster: Similar to Dictyostelium discoideum (Sl... 143 4e-32 UniRef50_A0DQ77 Cluster: Chromosome undetermined scaffold_6, who... 143 4e-32 UniRef50_UPI00006CC010 Cluster: hypothetical protein TTHERM_0041... 142 5e-32 UniRef50_UPI00015A6057 Cluster: UPI00015A6057 related cluster; n... 142 5e-32 UniRef50_A2DZ81 Cluster: Viral A-type inclusion protein, putativ... 142 5e-32 UniRef50_Q23PQ6 Cluster: Putative uncharacterized protein; n=1; ... 142 9e-32 UniRef50_A0CPT0 Cluster: Chromosome undetermined scaffold_23, wh... 142 9e-32 UniRef50_A2FP55 Cluster: Viral A-type inclusion protein, putativ... 141 1e-31 UniRef50_A0EEL6 Cluster: Chromosome undetermined scaffold_91, wh... 141 1e-31 UniRef50_Q2NHV1 Cluster: Putative uncharacterized protein; n=1; ... 141 2e-31 UniRef50_A0DKF0 Cluster: Chromosome undetermined scaffold_54, wh... 140 3e-31 UniRef50_Q9VJE5 Cluster: Restin homolog; n=4; Drosophila melanog... 140 3e-31 UniRef50_A0D7Y2 Cluster: Chromosome undetermined scaffold_40, wh... 140 4e-31 UniRef50_Q23DA0 Cluster: Putative uncharacterized protein; n=1; ... 139 5e-31 UniRef50_UPI0000F2D5B2 Cluster: PREDICTED: similar to centromere... 139 7e-31 UniRef50_UPI00004995B4 Cluster: myosin heavy chain; n=1; Entamoe... 139 7e-31 UniRef50_P25386 Cluster: Intracellular protein transport protein... 139 7e-31 UniRef50_A2ESM9 Cluster: Putative uncharacterized protein; n=1; ... 138 9e-31 UniRef50_UPI0000F1FE72 Cluster: PREDICTED: hypothetical protein;... 138 1e-30 UniRef50_UPI00006CFFCF Cluster: hypothetical protein TTHERM_0075... 138 1e-30 UniRef50_Q22W02 Cluster: Putative uncharacterized protein; n=1; ... 138 2e-30 UniRef50_A0EHS3 Cluster: Chromosome undetermined scaffold_97, wh... 138 2e-30 UniRef50_A0D3I1 Cluster: Chromosome undetermined scaffold_36, wh... 137 2e-30 UniRef50_Q4RT41 Cluster: Chromosome 12 SCAF14999, whole genome s... 137 3e-30 UniRef50_A0DQH1 Cluster: Chromosome undetermined scaffold_6, who... 137 3e-30 UniRef50_A0DI28 Cluster: Chromosome undetermined scaffold_51, wh... 136 4e-30 UniRef50_A0CUZ8 Cluster: Chromosome undetermined scaffold_29, wh... 136 4e-30 UniRef50_UPI0000E476CA Cluster: PREDICTED: similar to KIAA0445 p... 136 5e-30 UniRef50_Q23QE6 Cluster: Guanylate-binding protein, N-terminal d... 136 5e-30 UniRef50_UPI00006615CF Cluster: Homolog of Homo sapiens "Golgi a... 136 6e-30 UniRef50_Q4T928 Cluster: Chromosome undetermined SCAF7646, whole... 135 8e-30 UniRef50_A2ERV4 Cluster: Putative uncharacterized protein; n=1; ... 135 8e-30 UniRef50_Q7SHZ4 Cluster: Putative uncharacterized protein NCU006... 135 8e-30 UniRef50_Q8MSS1 Cluster: Protein lava lamp; n=1; Drosophila mela... 135 8e-30 UniRef50_A0CKT9 Cluster: Chromosome undetermined scaffold_20, wh... 135 1e-29 UniRef50_A0CCF8 Cluster: Chromosome undetermined scaffold_167, w... 135 1e-29 UniRef50_UPI00006CD8D3 Cluster: hypothetical protein TTHERM_0052... 134 1e-29 UniRef50_A0EEQ9 Cluster: Chromosome undetermined scaffold_92, wh... 134 1e-29 UniRef50_Q3V6T2 Cluster: Girdin; n=53; Euteleostomi|Rep: Girdin ... 134 1e-29 UniRef50_Q4N897 Cluster: Putative uncharacterized protein; n=2; ... 134 2e-29 UniRef50_A2ESN0 Cluster: Viral A-type inclusion protein, putativ... 134 2e-29 UniRef50_A0CFL4 Cluster: Chromosome undetermined scaffold_176, w... 134 2e-29 UniRef50_Q22NP6 Cluster: Putative uncharacterized protein; n=1; ... 134 3e-29 UniRef50_A0CUE6 Cluster: Chromosome undetermined scaffold_28, wh... 134 3e-29 UniRef50_UPI00006CB2D6 Cluster: Viral A-type inclusion protein r... 133 4e-29 UniRef50_A0DDB5 Cluster: Chromosome undetermined scaffold_46, wh... 133 4e-29 UniRef50_A0CZE8 Cluster: Chromosome undetermined scaffold_32, wh... 133 4e-29 UniRef50_A5DLM2 Cluster: Putative uncharacterized protein; n=1; ... 133 4e-29 UniRef50_A0DAF7 Cluster: Chromosome undetermined scaffold_43, wh... 132 6e-29 UniRef50_Q6CPF6 Cluster: Kluyveromyces lactis strain NRRL Y-1140... 132 6e-29 UniRef50_UPI0000E48979 Cluster: PREDICTED: similar to kinesin-re... 132 8e-29 UniRef50_A2DUI3 Cluster: Viral A-type inclusion protein, putativ... 132 8e-29 UniRef50_A0D2T6 Cluster: Chromosome undetermined scaffold_35, wh... 132 8e-29 UniRef50_UPI0000E47346 Cluster: PREDICTED: similar to Golgi-asso... 132 1e-28 UniRef50_Q8IBY8 Cluster: Putative uncharacterized protein PF07_0... 132 1e-28 UniRef50_Q7RGY2 Cluster: Repeat organellar protein-related; n=3;... 132 1e-28 UniRef50_Q54NP8 Cluster: Kinesin 4; n=3; Dictyostelium discoideu... 132 1e-28 UniRef50_A2DLG1 Cluster: Viral A-type inclusion protein, putativ... 132 1e-28 UniRef50_UPI00006CA4F0 Cluster: Viral A-type inclusion protein r... 131 1e-28 UniRef50_Q4Q3D8 Cluster: Putative uncharacterized protein; n=3; ... 131 1e-28 UniRef50_O96133 Cluster: Putative uncharacterized protein PFB014... 131 1e-28 UniRef50_Q15075 Cluster: Early endosome antigen 1; n=30; Euteleo... 131 1e-28 UniRef50_Q09EF7 Cluster: Putative uncharacterized protein; n=8; ... 131 2e-28 UniRef50_A0CGX1 Cluster: Chromosome undetermined scaffold_18, wh... 131 2e-28 UniRef50_A0BCM0 Cluster: Chromosome undetermined scaffold_10, wh... 131 2e-28 UniRef50_Q22AS4 Cluster: Putative uncharacterized protein; n=1; ... 130 2e-28 UniRef50_A2F8N8 Cluster: Putative uncharacterized protein; n=2; ... 130 2e-28 UniRef50_Q6RT24 Cluster: Centromere associated protein-E; n=13; ... 130 3e-28 UniRef50_Q9BJD3 Cluster: Major plasmodial myosin heavy chain; n=... 130 3e-28 UniRef50_A0ECU5 Cluster: Chromosome undetermined scaffold_9, who... 130 3e-28 UniRef50_A0BTE2 Cluster: Chromosome undetermined scaffold_127, w... 130 4e-28 UniRef50_Q7RIN9 Cluster: Putative uncharacterized protein PY0357... 129 5e-28 UniRef50_UPI00006A154D Cluster: Centrosomal protein 2 (Centrosom... 129 7e-28 UniRef50_A0D4Y2 Cluster: Chromosome undetermined scaffold_38, wh... 129 7e-28 UniRef50_Q23E34 Cluster: Putative uncharacterized protein; n=2; ... 128 9e-28 UniRef50_UPI00006CCC54 Cluster: hypothetical protein TTHERM_0033... 128 1e-27 UniRef50_A4S4A9 Cluster: Predicted protein; n=2; Viridiplantae|R... 128 1e-27 UniRef50_UPI0000D57874 Cluster: PREDICTED: similar to GRIP and c... 128 2e-27 UniRef50_Q23KF2 Cluster: Putative uncharacterized protein; n=1; ... 128 2e-27 UniRef50_Q16FM5 Cluster: LL5 beta protein, putative; n=2; Aedes ... 128 2e-27 UniRef50_A0BIX7 Cluster: Chromosome undetermined scaffold_11, wh... 128 2e-27 UniRef50_A0NCN7 Cluster: ENSANGP00000031886; n=1; Anopheles gamb... 127 2e-27 UniRef50_A2DGV9 Cluster: Viral A-type inclusion protein, putativ... 127 3e-27 UniRef50_A0DR44 Cluster: Chromosome undetermined scaffold_6, who... 127 3e-27 UniRef50_UPI00006CB6DE Cluster: hypothetical protein TTHERM_0049... 126 4e-27 UniRef50_Q52L24 Cluster: LOC733209 protein; n=1; Xenopus laevis|... 126 4e-27 UniRef50_Q7NBF8 Cluster: Putative uncharacterized protein; n=1; ... 126 4e-27 UniRef50_Q16IF0 Cluster: Condensin, SMC5-subunit, putative; n=1;... 126 4e-27 UniRef50_A0E6F4 Cluster: Chromosome undetermined scaffold_8, who... 126 4e-27 UniRef50_A7DN60 Cluster: Chromosome segregation ATPase-like prot... 126 4e-27 UniRef50_A0DA04 Cluster: Chromosome undetermined scaffold_42, wh... 126 5e-27 UniRef50_A0CJD5 Cluster: Chromosome undetermined scaffold_2, who... 126 5e-27 UniRef50_O61308 Cluster: 227 kDa spindle- and centromere-associa... 126 5e-27 UniRef50_Q8IWJ2 Cluster: GRIP and coiled-coil domain-containing ... 126 5e-27 UniRef50_Q245H6 Cluster: Putative uncharacterized protein; n=1; ... 126 7e-27 UniRef50_Q22TK4 Cluster: Putative uncharacterized protein; n=1; ... 126 7e-27 UniRef50_A0CFQ2 Cluster: Chromosome undetermined scaffold_177, w... 126 7e-27 UniRef50_A0BYX7 Cluster: Chromosome undetermined scaffold_138, w... 126 7e-27 UniRef50_UPI00015B5164 Cluster: PREDICTED: similar to ENSANGP000... 125 9e-27 UniRef50_UPI00006CB7E3 Cluster: Viral A-type inclusion protein r... 125 9e-27 UniRef50_O42263 Cluster: Kinesin-related protein; n=2; Xenopus|R... 125 9e-27 UniRef50_A2D7K4 Cluster: Putative uncharacterized protein; n=1; ... 125 9e-27 UniRef50_Q4D6G7 Cluster: Putative uncharacterized protein; n=4; ... 125 1e-26 UniRef50_Q23Q31 Cluster: Viral A-type inclusion protein repeat c... 125 1e-26 UniRef50_P49454 Cluster: Centromere protein F; n=15; Eutheria|Re... 125 1e-26 UniRef50_UPI0001509DA0 Cluster: hypothetical protein TTHERM_0053... 124 2e-26 UniRef50_UPI00006CC401 Cluster: hypothetical protein TTHERM_0013... 124 2e-26 UniRef50_UPI00006CAB41 Cluster: hypothetical protein TTHERM_0078... 124 2e-26 UniRef50_Q22CJ7 Cluster: Putative uncharacterized protein; n=1; ... 124 2e-26 UniRef50_UPI00006CD102 Cluster: Kinesin motor domain containing ... 124 2e-26 UniRef50_Q9XZE3 Cluster: Myosin heavy chain; n=1; Amoeba proteus... 124 2e-26 UniRef50_Q24GP7 Cluster: Putative uncharacterized protein; n=2; ... 124 2e-26 UniRef50_A0CVZ5 Cluster: Chromosome undetermined scaffold_3, who... 124 2e-26 UniRef50_P75471 Cluster: Cytadherence high molecular weight prot... 124 2e-26 UniRef50_A5DD85 Cluster: Putative uncharacterized protein; n=1; ... 124 3e-26 UniRef50_UPI000051A547 Cluster: PREDICTED: similar to CG6129-PB,... 123 4e-26 UniRef50_UPI0000ECA83C Cluster: Centrosome-associated protein CE... 123 4e-26 UniRef50_Q57UD0 Cluster: Kinesin K39, putative; n=1; Trypanosoma... 123 4e-26 UniRef50_Q4E572 Cluster: Antigenic protein, putative; n=2; Trypa... 123 4e-26 UniRef50_A3LZ88 Cluster: Myosin-1; n=1; Pichia stipitis|Rep: Myo... 123 4e-26 UniRef50_Q54JG6 Cluster: Putative uncharacterized protein; n=1; ... 123 5e-26 UniRef50_Q22AQ6 Cluster: Putative uncharacterized protein; n=1; ... 123 5e-26 UniRef50_A2EJ44 Cluster: Viral A-type inclusion protein, putativ... 123 5e-26 UniRef50_A0DV70 Cluster: Chromosome undetermined scaffold_65, wh... 123 5e-26 UniRef50_A0CTT0 Cluster: Chromosome undetermined scaffold_27, wh... 123 5e-26 UniRef50_P08799 Cluster: Myosin-2 heavy chain, non muscle; n=5; ... 123 5e-26 UniRef50_Q0IVY3 Cluster: Os10g0547000 protein; n=4; Oryza sativa... 122 6e-26 UniRef50_A0DSK6 Cluster: Chromosome undetermined scaffold_61, wh... 122 6e-26 UniRef50_A4QRL5 Cluster: Putative uncharacterized protein; n=1; ... 122 6e-26 UniRef50_UPI00015B5411 Cluster: PREDICTED: similar to SD07366p; ... 122 8e-26 UniRef50_Q4S7F6 Cluster: Chromosome 13 SCAF14715, whole genome s... 122 8e-26 UniRef50_Q115P0 Cluster: Chromosome segregation ATPase-like prot... 122 8e-26 UniRef50_Q232U4 Cluster: Putative uncharacterized protein; n=1; ... 122 8e-26 UniRef50_A0D4V9 Cluster: Chromosome undetermined scaffold_38, wh... 122 8e-26 UniRef50_A0CY92 Cluster: Chromosome undetermined scaffold_31, wh... 122 8e-26 UniRef50_A0CY31 Cluster: Chromosome undetermined scaffold_30, wh... 122 8e-26 UniRef50_A0C7H6 Cluster: Chromosome undetermined scaffold_155, w... 122 8e-26 UniRef50_A5E429 Cluster: Putative uncharacterized protein; n=1; ... 122 8e-26 UniRef50_UPI00006A0892 Cluster: Hook-related protein 1; n=1; Xen... 122 1e-25 UniRef50_Q155P7 Cluster: LEK1; n=19; Glires|Rep: LEK1 - Mus musc... 122 1e-25 UniRef50_A0DQA4 Cluster: Chromosome undetermined scaffold_6, who... 122 1e-25 UniRef50_A0CHZ3 Cluster: Chromosome undetermined scaffold_186, w... 122 1e-25 UniRef50_A0CGR6 Cluster: Chromosome undetermined scaffold_18, wh... 122 1e-25 UniRef50_A0C824 Cluster: Chromosome undetermined scaffold_157, w... 122 1e-25 UniRef50_Q10RF6 Cluster: Viral A-type inclusion protein repeat c... 121 1e-25 UniRef50_A7R618 Cluster: Chromosome undetermined scaffold_1129, ... 121 1e-25 UniRef50_A2FMF0 Cluster: Putative uncharacterized protein; n=1; ... 121 1e-25 UniRef50_UPI000150A28F Cluster: hypothetical protein TTHERM_0046... 121 2e-25 UniRef50_UPI00006CD2BD Cluster: Viral A-type inclusion protein r... 121 2e-25 UniRef50_Q612W7 Cluster: Putative uncharacterized protein CBG165... 121 2e-25 UniRef50_Q4QFM2 Cluster: Kinesin K39, putative; n=14; root|Rep: ... 121 2e-25 UniRef50_A2G9D2 Cluster: Putative uncharacterized protein; n=1; ... 121 2e-25 UniRef50_A0BM71 Cluster: Chromosome undetermined scaffold_115, w... 121 2e-25 UniRef50_UPI00006CBB68 Cluster: Kinesin motor domain containing ... 120 3e-25 UniRef50_UPI00015A629B Cluster: UPI00015A629B related cluster; n... 120 3e-25 UniRef50_Q7QII2 Cluster: ENSANGP00000005723; n=1; Anopheles gamb... 120 3e-25 UniRef50_O74424 Cluster: Nucleoporin nup211; n=1; Schizosaccharo... 120 3e-25 UniRef50_UPI0000F20708 Cluster: PREDICTED: similar to Hyperion p... 120 3e-25 UniRef50_Q869R0 Cluster: Similar to Entamoeba histolytica. Myosi... 120 3e-25 UniRef50_A2EET7 Cluster: Viral A-type inclusion protein, putativ... 120 3e-25 UniRef50_A0DXA7 Cluster: Chromosome undetermined scaffold_68, wh... 120 3e-25 UniRef50_Q14789 Cluster: Golgin subfamily B member 1; n=25; Euth... 120 3e-25 UniRef50_UPI0001556340 Cluster: PREDICTED: similar to golgi auto... 120 4e-25 UniRef50_UPI0000E80429 Cluster: PREDICTED: similar to CENPE vari... 120 4e-25 UniRef50_UPI00006CBA9F Cluster: Viral A-type inclusion protein r... 120 4e-25 UniRef50_Q22HK2 Cluster: Viral A-type inclusion protein repeat c... 120 4e-25 UniRef50_A0CQ96 Cluster: Chromosome undetermined scaffold_24, wh... 120 4e-25 UniRef50_A0BI23 Cluster: Chromosome undetermined scaffold_109, w... 120 4e-25 UniRef50_Q02455 Cluster: Protein MLP1; n=2; Saccharomyces cerevi... 120 4e-25 UniRef50_UPI000155D3DD Cluster: PREDICTED: similar to centromere... 119 6e-25 UniRef50_Q63ZU6 Cluster: LOC494731 protein; n=6; Tetrapoda|Rep: ... 119 6e-25 UniRef50_Q585H6 Cluster: Putative uncharacterized protein; n=2; ... 119 6e-25 UniRef50_Q5A0Z6 Cluster: Putative uncharacterized protein; n=3; ... 119 6e-25 UniRef50_P54697 Cluster: Myosin IJ heavy chain; n=3; Dictyosteli... 119 6e-25 UniRef50_UPI00004D936A Cluster: Centrosomal protein 2 (Centrosom... 119 8e-25 UniRef50_Q6BFF0 Cluster: Guanylate nucleotide binding protein, p... 119 8e-25 UniRef50_A5KBH9 Cluster: Putative uncharacterized protein; n=1; ... 119 8e-25 UniRef50_A2FMV8 Cluster: Surface antigen repeat-containing prote... 119 8e-25 UniRef50_A2F8Y3 Cluster: Putative uncharacterized protein; n=8; ... 119 8e-25 UniRef50_A0D367 Cluster: Chromosome undetermined scaffold_36, wh... 119 8e-25 UniRef50_A0CU18 Cluster: Chromosome undetermined scaffold_28, wh... 119 8e-25 UniRef50_Q4PGJ7 Cluster: Putative uncharacterized protein; n=1; ... 119 8e-25 UniRef50_UPI00006CC842 Cluster: hypothetical protein TTHERM_0028... 118 1e-24 UniRef50_Q25662 Cluster: Repeat organellar protein; n=5; Plasmod... 118 1e-24 UniRef50_A2FNC4 Cluster: Variable membrane protein, putative; n=... 118 1e-24 UniRef50_P30622 Cluster: CAP-Gly domain-containing linker protei... 118 1e-24 UniRef50_UPI0000D563E7 Cluster: PREDICTED: similar to Centromeri... 118 1e-24 UniRef50_UPI00006CB656 Cluster: hypothetical protein TTHERM_0044... 118 1e-24 UniRef50_Q233E2 Cluster: Putative uncharacterized protein; n=1; ... 118 1e-24 UniRef50_Q22RB8 Cluster: Putative uncharacterized protein; n=1; ... 118 1e-24 UniRef50_Q22257 Cluster: Putative uncharacterized protein hcp-2;... 118 1e-24 UniRef50_A0DAF8 Cluster: Chromosome undetermined scaffold_43, wh... 118 1e-24 UniRef50_UPI0000F204C0 Cluster: PREDICTED: similar to Viral A-ty... 118 2e-24 UniRef50_UPI0000DB748D Cluster: PREDICTED: similar to Megator CG... 118 2e-24 UniRef50_O97291 Cluster: Putative uncharacterized protein MAL3P7... 118 2e-24 UniRef50_A7TIT7 Cluster: Putative uncharacterized protein; n=1; ... 118 2e-24 UniRef50_UPI00006CD8BD Cluster: hypothetical protein TTHERM_0052... 117 2e-24 UniRef50_Q4T443 Cluster: Chromosome undetermined SCAF9830, whole... 117 2e-24 UniRef50_Q949K0 Cluster: Putative centromere protein; n=1; Solan... 117 2e-24 UniRef50_A2FTZ2 Cluster: Repeated sequence found in lipoprotein ... 117 2e-24 UniRef50_A2F6M0 Cluster: Putative uncharacterized protein; n=1; ... 117 2e-24 UniRef50_A0D7Y1 Cluster: Chromosome undetermined scaffold_40, wh... 117 2e-24 UniRef50_A7TNK0 Cluster: Putative uncharacterized protein; n=1; ... 117 2e-24 UniRef50_P35749 Cluster: Myosin-11; n=123; Eukaryota|Rep: Myosin... 117 2e-24 UniRef50_UPI0000E48EEB Cluster: PREDICTED: similar to Viral A-ty... 117 3e-24 UniRef50_UPI00004999D2 Cluster: conserved hypothetical protein; ... 117 3e-24 UniRef50_A0E680 Cluster: Chromosome undetermined scaffold_8, who... 117 3e-24 UniRef50_Q15643 Cluster: Thyroid receptor-interacting protein 11... 117 3e-24 UniRef50_UPI0000E46F7D Cluster: PREDICTED: similar to Viral A-ty... 116 4e-24 UniRef50_A7QNA8 Cluster: Chromosome chr2 scaffold_132, whole gen... 116 4e-24 UniRef50_Q7QTJ5 Cluster: GLP_375_25300_33276; n=1; Giardia lambl... 116 4e-24 UniRef50_Q4YBL9 Cluster: Putative uncharacterized protein; n=5; ... 116 4e-24 UniRef50_Q22F30 Cluster: Putative uncharacterized protein; n=1; ... 116 4e-24 UniRef50_A4HCH0 Cluster: Putative uncharacterized protein; n=1; ... 116 4e-24 UniRef50_A0CKR1 Cluster: Chromosome undetermined scaffold_2, who... 116 4e-24 UniRef50_UPI0000DB7211 Cluster: PREDICTED: similar to Stretchin-... 116 5e-24 UniRef50_UPI0000D56108 Cluster: PREDICTED: similar to CG18304-PA... 116 5e-24 UniRef50_Q8IIF6 Cluster: Putative uncharacterized protein; n=3; ... 116 5e-24 UniRef50_A2F0Q2 Cluster: Putative uncharacterized protein; n=1; ... 116 5e-24 UniRef50_UPI00006CFF95 Cluster: hypothetical protein TTHERM_0072... 116 7e-24 UniRef50_Q0DUY3 Cluster: Os03g0161100 protein; n=1; Oryza sativa... 116 7e-24 UniRef50_Q6A178 Cluster: Myosin tail 1 protein; n=4; Cryptospori... 116 7e-24 UniRef50_A0BXA6 Cluster: Chromosome undetermined scaffold_134, w... 115 9e-24 UniRef50_A2FHD4 Cluster: Trichohyalin, putative; n=1; Trichomona... 115 1e-23 UniRef50_A0DEE6 Cluster: Chromosome undetermined scaffold_48, wh... 115 1e-23 UniRef50_A0CX58 Cluster: Chromosome undetermined scaffold_3, who... 115 1e-23 UniRef50_Q8I659 Cluster: Putative uncharacterized protein PFB076... 114 2e-23 UniRef50_Q8I525 Cluster: Putative uncharacterized protein; n=1; ... 114 2e-23 UniRef50_Q1RLC7 Cluster: Zinc finger protein; n=1; Ciona intesti... 114 2e-23 UniRef50_O76447 Cluster: Holocentric chromosome binding protein ... 114 2e-23 UniRef50_A0CS47 Cluster: Chromosome undetermined scaffold_26, wh... 114 2e-23 UniRef50_A0C6A2 Cluster: Chromosome undetermined scaffold_151, w... 114 2e-23 UniRef50_Q2SR09 Cluster: Membrane protein, putative; n=1; Mycopl... 113 3e-23 UniRef50_Q7XEH4 Cluster: Expressed protein; n=5; Oryza sativa|Re... 113 3e-23 UniRef50_Q7RC59 Cluster: Putative uncharacterized protein PY0592... 113 3e-23 UniRef50_Q21022 Cluster: Putative uncharacterized protein; n=2; ... 113 3e-23 UniRef50_Q16XH2 Cluster: RHC18, putative; n=1; Aedes aegypti|Rep... 113 3e-23 UniRef50_A0EB09 Cluster: Chromosome undetermined scaffold_87, wh... 113 3e-23 UniRef50_A0DCN4 Cluster: Chromosome undetermined scaffold_45, wh... 113 3e-23 UniRef50_Q9BZF9 Cluster: Uveal autoantigen with coiled-coil doma... 113 3e-23 UniRef50_UPI0000E471AC Cluster: PREDICTED: similar to Hook-relat... 113 4e-23 UniRef50_UPI00006CBC08 Cluster: hypothetical protein TTHERM_0093... 113 4e-23 UniRef50_Q6E502 Cluster: Ninein-like protein; n=3; Euteleostomi|... 113 4e-23 UniRef50_Q4SEM9 Cluster: Chromosome undetermined SCAF14615, whol... 113 4e-23 UniRef50_Q2SR11 Cluster: Membrane protein, putative; n=3; Mycopl... 113 4e-23 UniRef50_A7HKY7 Cluster: S-layer domain protein; n=2; cellular o... 113 4e-23 UniRef50_A2DER5 Cluster: Putative uncharacterized protein; n=2; ... 113 4e-23 UniRef50_Q90339 Cluster: Myosin heavy chain, fast skeletal muscl... 113 4e-23 UniRef50_UPI00015B58F5 Cluster: PREDICTED: similar to kinesin-re... 112 7e-23 UniRef50_A0DSF3 Cluster: Chromosome undetermined scaffold_61, wh... 112 7e-23 UniRef50_UPI0000DB6E46 Cluster: PREDICTED: similar to restin iso... 112 9e-23 UniRef50_UPI0000D55B3E Cluster: PREDICTED: similar to CG33206-PA... 112 9e-23 UniRef50_UPI00006CA722 Cluster: hypothetical protein TTHERM_0084... 112 9e-23 UniRef50_Q57UV7 Cluster: Kinesin, putative; n=1; Trypanosoma bru... 112 9e-23 UniRef50_Q4CT56 Cluster: Putative uncharacterized protein; n=2; ... 112 9e-23 UniRef50_A0E285 Cluster: Chromosome undetermined scaffold_74, wh... 112 9e-23 UniRef50_Q7PVQ7 Cluster: ENSANGP00000023159; n=1; Anopheles gamb... 111 1e-22 UniRef50_Q6LF09 Cluster: Putative uncharacterized protein; n=6; ... 111 1e-22 UniRef50_A2ETQ3 Cluster: Viral A-type inclusion protein, putativ... 111 1e-22 UniRef50_A5DJG0 Cluster: Putative uncharacterized protein; n=1; ... 111 1e-22 UniRef50_UPI00006CB786 Cluster: hypothetical protein TTHERM_0034... 111 2e-22 UniRef50_Q9XIP6 Cluster: F13O11.30 protein; n=3; Arabidopsis tha... 111 2e-22 UniRef50_Q00ZD8 Cluster: Myosin class II heavy chain; n=2; Virid... 111 2e-22 UniRef50_P92021 Cluster: Putative uncharacterized protein eea-1;... 111 2e-22 UniRef50_A0BQG1 Cluster: Chromosome undetermined scaffold_120, w... 111 2e-22 UniRef50_Q6BNV2 Cluster: Debaryomyces hansenii chromosome E of s... 111 2e-22 UniRef50_UPI000155602C Cluster: PREDICTED: similar to pericentri... 111 2e-22 UniRef50_UPI00015A769C Cluster: UPI00015A769C related cluster; n... 111 2e-22 UniRef50_UPI0000ECD074 Cluster: Golgin subfamily B member 1 (Gia... 111 2e-22 UniRef50_Q4RLC8 Cluster: Chromosome 21 SCAF15022, whole genome s... 111 2e-22 UniRef50_A2FRC3 Cluster: Putative uncharacterized protein; n=1; ... 111 2e-22 UniRef50_UPI00004D7618 Cluster: Hook-related protein 1; n=1; Xen... 110 3e-22 UniRef50_Q8RCY8 Cluster: ATPase involved in DNA repair; n=3; The... 110 3e-22 UniRef50_Q4DQS9 Cluster: Putative uncharacterized protein; n=2; ... 110 3e-22 UniRef50_Q4D1D3 Cluster: Myosin heavy chain, putative; n=4; Tryp... 110 3e-22 UniRef50_A2E4S4 Cluster: Viral A-type inclusion protein, putativ... 110 3e-22 UniRef50_A2DXJ2 Cluster: Viral A-type inclusion protein, putativ... 110 3e-22 UniRef50_A0D5W3 Cluster: Chromosome undetermined scaffold_39, wh... 110 3e-22 UniRef50_Q59UF5 Cluster: Potential GRIP domain Golgi protein; n=... 110 3e-22 UniRef50_P32380 Cluster: Protein NUF1; n=2; Saccharomyces cerevi... 110 3e-22 UniRef50_UPI0001509CEA Cluster: hypothetical protein TTHERM_0031... 110 4e-22 UniRef50_A2G463 Cluster: Putative uncharacterized protein; n=1; ... 110 4e-22 UniRef50_A0E891 Cluster: Chromosome undetermined scaffold_82, wh... 110 4e-22 UniRef50_Q6FTH3 Cluster: Similar to sp|Q02455 Saccharomyces cere... 110 4e-22 UniRef50_Q23ZG7 Cluster: Peptidase family M1 containing protein;... 109 5e-22 UniRef50_A0CQS2 Cluster: Chromosome undetermined scaffold_24, wh... 109 5e-22 UniRef50_A0BBG4 Cluster: Chromosome undetermined scaffold_1, who... 109 5e-22 UniRef50_Q6VGS5 Cluster: Protein Daple; n=23; Amniota|Rep: Prote... 109 5e-22 UniRef50_UPI00006CEB8C Cluster: Viral A-type inclusion protein r... 109 6e-22 UniRef50_Q9VXU2 Cluster: CG33206-PA, isoform A; n=2; Drosophila ... 109 6e-22 UniRef50_Q22GJ1 Cluster: Putative uncharacterized protein; n=1; ... 109 6e-22 UniRef50_Q7S6K9 Cluster: Putative uncharacterized protein NCU048... 109 6e-22 UniRef50_UPI0000D5750B Cluster: PREDICTED: similar to CG8274-PA;... 109 8e-22 UniRef50_Q8T8Q5 Cluster: SD05887p; n=3; Sophophora|Rep: SD05887p... 109 8e-22 UniRef50_A0EI89 Cluster: Chromosome undetermined scaffold_98, wh... 109 8e-22 UniRef50_UPI000065E69E Cluster: Homolog of Brachydanio rerio "Ve... 108 1e-21 UniRef50_Q381P0 Cluster: Putative uncharacterized protein; n=1; ... 108 1e-21 UniRef50_Q22SU9 Cluster: Putative uncharacterized protein; n=1; ... 108 1e-21 UniRef50_A4HW55 Cluster: Kinesin K39, putative; n=2; Leishmania|... 108 1e-21 UniRef50_A2F5K7 Cluster: Putative uncharacterized protein; n=1; ... 108 1e-21 UniRef50_A2DDW4 Cluster: Putative uncharacterized protein; n=1; ... 108 1e-21 UniRef50_A0DRJ3 Cluster: Chromosome undetermined scaffold_60, wh... 108 1e-21 UniRef50_A0CJH0 Cluster: Chromosome undetermined scaffold_2, who... 108 1e-21 UniRef50_UPI00006D00EC Cluster: hypothetical protein TTHERM_0082... 108 1e-21 UniRef50_UPI00006CB5F6 Cluster: hypothetical protein TTHERM_0053... 108 1e-21 UniRef50_Q22X39 Cluster: Putative uncharacterized protein; n=1; ... 108 1e-21 UniRef50_A2EC28 Cluster: Viral A-type inclusion protein, putativ... 108 1e-21 UniRef50_A0DLY5 Cluster: Chromosome undetermined scaffold_56, wh... 108 1e-21 UniRef50_A0C8T7 Cluster: Chromosome undetermined scaffold_159, w... 108 1e-21 UniRef50_A0BL16 Cluster: Chromosome undetermined scaffold_113, w... 108 1e-21 UniRef50_UPI00006CC0B5 Cluster: hypothetical protein TTHERM_0021... 107 2e-21 UniRef50_Q4RJ17 Cluster: Chromosome 1 SCAF15039, whole genome sh... 107 2e-21 UniRef50_A2DQ51 Cluster: Putative uncharacterized protein; n=1; ... 107 2e-21 UniRef50_A0EAD2 Cluster: Chromosome undetermined scaffold_86, wh... 107 2e-21 UniRef50_A0CHD4 Cluster: Chromosome undetermined scaffold_180, w... 107 2e-21 UniRef50_UPI000150A032 Cluster: hypothetical protein TTHERM_0034... 107 2e-21 UniRef50_UPI0000D56AC0 Cluster: PREDICTED: similar to CG30337-PB... 107 2e-21 UniRef50_UPI00006CBDCB Cluster: hypothetical protein TTHERM_0031... 107 2e-21 UniRef50_Q4SSK2 Cluster: Chromosome 15 SCAF14367, whole genome s... 107 2e-21 UniRef50_Q5CHP8 Cluster: T10G3.5; n=2; Cryptosporidium|Rep: T10G... 107 2e-21 UniRef50_Q54DR3 Cluster: Calponin homology (CH) domain-containin... 107 2e-21 UniRef50_A2DES2 Cluster: Putative uncharacterized protein; n=1; ... 107 2e-21 UniRef50_Q2SSN4 Cluster: Lipoprotein, putative; n=3; Mycoplasma|... 107 3e-21 UniRef50_A6C0X8 Cluster: Putative uncharacterized protein; n=1; ... 107 3e-21 UniRef50_Q8I5X5 Cluster: Putative uncharacterized protein; n=1; ... 107 3e-21 UniRef50_Q22AV6 Cluster: Putative uncharacterized protein; n=1; ... 107 3e-21 UniRef50_O00905 Cluster: Putative uncharacterized protein; n=1; ... 107 3e-21 UniRef50_A0DAV2 Cluster: Chromosome undetermined scaffold_43, wh... 107 3e-21 UniRef50_A0CTR2 Cluster: Chromosome undetermined scaffold_27, wh... 107 3e-21 UniRef50_A5E4B9 Cluster: Putative uncharacterized protein; n=1; ... 107 3e-21 UniRef50_Q7RI76 Cluster: Putative uncharacterized protein PY0375... 106 4e-21 UniRef50_UPI0000E4801E Cluster: PREDICTED: similar to sarcoma an... 106 6e-21 UniRef50_UPI00004D1979 Cluster: centromere protein F (350/400kD)... 106 6e-21 UniRef50_Q54L07 Cluster: Zipper-like domain-containing protein; ... 106 6e-21 UniRef50_Q22WE5 Cluster: Leucine Rich Repeat family protein; n=1... 106 6e-21 UniRef50_A0BNU4 Cluster: Chromosome undetermined scaffold_119, w... 106 6e-21 UniRef50_P70012 Cluster: Nuclear/mitotic apparatus protein; n=3;... 105 8e-21 UniRef50_Q22MK1 Cluster: Putative uncharacterized protein; n=1; ... 105 8e-21 UniRef50_A2G5Q5 Cluster: Putative uncharacterized protein; n=1; ... 105 8e-21 UniRef50_A2FAD3 Cluster: Putative uncharacterized protein; n=1; ... 105 8e-21 UniRef50_A2E4A2 Cluster: Putative uncharacterized protein; n=1; ... 105 8e-21 UniRef50_A0DU61 Cluster: Chromosome undetermined scaffold_64, wh... 105 8e-21 UniRef50_A0D1B6 Cluster: Chromosome undetermined scaffold_34, wh... 105 8e-21 UniRef50_A2FMP7 Cluster: Putative uncharacterized protein; n=1; ... 105 1e-20 UniRef50_A2F798 Cluster: Putative uncharacterized protein; n=1; ... 105 1e-20 UniRef50_A2ESG7 Cluster: Viral A-type inclusion protein, putativ... 105 1e-20 UniRef50_A7TM73 Cluster: Putative uncharacterized protein; n=1; ... 105 1e-20 UniRef50_P12270 Cluster: Nucleoprotein TPR; n=57; Euteleostomi|R... 105 1e-20 UniRef50_Q11102 Cluster: Putative protein tag-278; n=2; Caenorha... 105 1e-20 UniRef50_P10567 Cluster: Paramyosin; n=23; Bilateria|Rep: Paramy... 105 1e-20 UniRef50_UPI0000E468ED Cluster: PREDICTED: similar to Restin (Re... 105 1e-20 UniRef50_Q702H4 Cluster: FYVE and coiled-coil; n=2; Gallus gallu... 105 1e-20 UniRef50_Q17E94 Cluster: Putative uncharacterized protein; n=2; ... 105 1e-20 UniRef50_A0BRK7 Cluster: Chromosome undetermined scaffold_123, w... 105 1e-20 UniRef50_Q08SC3 Cluster: Adventurous gliding protein Z; n=1; Sti... 104 2e-20 UniRef50_Q9NCG0 Cluster: Kinesin-like kinetochore motor protein ... 104 2e-20 UniRef50_Q22RA5 Cluster: Putative uncharacterized protein; n=1; ... 104 2e-20 UniRef50_A7SQE6 Cluster: Predicted protein; n=1; Nematostella ve... 104 2e-20 UniRef50_A1Z8P9 Cluster: CG8274-PA; n=4; Drosophila melanogaster... 104 2e-20 UniRef50_Q6BI71 Cluster: Similar to CA4409|IPF13151 Candida albi... 104 2e-20 UniRef50_UPI00006CFADD Cluster: hypothetical protein TTHERM_0047... 104 2e-20 UniRef50_O23037 Cluster: YUP8H12.6 protein; n=3; Arabidopsis tha... 104 2e-20 UniRef50_Q382P4 Cluster: Putative uncharacterized protein; n=1; ... 104 2e-20 UniRef50_A0CXR3 Cluster: Chromosome undetermined scaffold_30, wh... 104 2e-20 UniRef50_A0BCU6 Cluster: Chromosome undetermined scaffold_10, wh... 104 2e-20 UniRef50_Q6BY65 Cluster: Debaryomyces hansenii chromosome A of s... 104 2e-20 UniRef50_UPI0000E49858 Cluster: PREDICTED: hypothetical protein;... 103 3e-20 UniRef50_UPI0000DB6FEB Cluster: PREDICTED: similar to CENP-F kin... 103 3e-20 UniRef50_UPI000023F55C Cluster: hypothetical protein FG05337.1; ... 103 3e-20 UniRef50_UPI00005679AE Cluster: UPI00005679AE related cluster; n... 103 3e-20 UniRef50_Q4RZS5 Cluster: Chromosome 18 SCAF14786, whole genome s... 103 3e-20 UniRef50_Q6FPV2 Cluster: Similar to sp|P08964 Saccharomyces cere... 103 3e-20 UniRef50_Q5AMW9 Cluster: Putative uncharacterized protein; n=2; ... 103 3e-20 UniRef50_Q0U4W1 Cluster: Putative uncharacterized protein; n=1; ... 103 3e-20 UniRef50_A0PJP3 Cluster: Putative uncharacterized protein; n=2; ... 103 4e-20 UniRef50_Q4Y6I2 Cluster: Putative uncharacterized protein; n=4; ... 103 4e-20 UniRef50_A2FU10 Cluster: Putative uncharacterized protein; n=1; ... 103 4e-20 UniRef50_A0CFU5 Cluster: Chromosome undetermined scaffold_177, w... 103 4e-20 UniRef50_A0BJN6 Cluster: Chromosome undetermined scaffold_110, w... 103 4e-20 UniRef50_O15078 Cluster: Centrosomal protein Cep290; n=48; Eumet... 103 4e-20 UniRef50_Q00VG0 Cluster: Homology to unknown gene; n=1; Ostreoco... 103 5e-20 UniRef50_Q22869 Cluster: Non-muscle myosin heavy chain II; n=3; ... 103 5e-20 UniRef50_A2DZF5 Cluster: Putative uncharacterized protein; n=1; ... 103 5e-20 UniRef50_A0CUE5 Cluster: Chromosome undetermined scaffold_28, wh... 103 5e-20 UniRef50_UPI00006CD295 Cluster: Protein kinase domain containing... 102 7e-20 UniRef50_A7PHV3 Cluster: Chromosome chr13 scaffold_17, whole gen... 102 7e-20 UniRef50_A0BP42 Cluster: Chromosome undetermined scaffold_12, wh... 102 7e-20 UniRef50_P62134 Cluster: DNA double-strand break repair rad50 AT... 102 7e-20 UniRef50_P40457 Cluster: Protein MLP2; n=2; Saccharomyces cerevi... 102 7e-20 >UniRef50_UPI0000D55C9F Cluster: PREDICTED: similar to Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1); n=1; Tribolium castaneum|Rep: PREDICTED: similar to Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1) - Tribolium castaneum Length = 2217 Score = 251 bits (615), Expect = 1e-64 Identities = 244/1047 (23%), Positives = 473/1047 (45%), Gaps = 61/1047 (5%) Query: 470 TNTEDVNEIAKVQEQLKQELNDEIKDV--NVKDLIEKLKSAEE--QITQLNDEIDAANKN 525 TN +I++ E L+ +L E + +++L KL+ ++E ++ +L +++ ANKN Sbjct: 267 TNANLEKQISEKAEDLELDLKTENSRLLDKIRELEVKLEESQESEEVAKLKKQLEEANKN 326 Query: 526 MIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHL 585 MIKVK+ HK K+K++ K I++F K+SD+N EIV+L E LSQK+AELEEEKG+LQL L Sbjct: 327 MIKVKAQHKSKVKELTKKIESFKKMSDANAEIVKLEAENSRLSQKIAELEEEKGSLQLKL 386 Query: 586 VDYDSGR----MIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVE 641 V+ DS + E+++ K+ + E + E + K IS+LES E+ + + D + Sbjct: 387 VESDSNKGSETERENELENKIQDHERMLEEKDKIISILES-------EISRSKTEIDNLN 439 Query: 642 DKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLEN 701 +KL + QV SE+ S+ EEQ++ + + K++L E + +KEQL ++ L+ Sbjct: 440 EKL-------NGQVKSEMVSIQFEEQLERVESEKRQLVEENERICKEKEQLGEQLEQLKK 492 Query: 702 DKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERD 761 +K+++ KL++YIQENM+L DKLEK+SAEK+S I E Q + ++A + D Sbjct: 493 EKQEVATKLEHYIQENMELIDKLEKLSAEKVSS-AESIEIVENLTQQEKLELEAYHKNLD 551 Query: 762 LYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQED 821 L N+++ S+ L ES+ + + L +K + +E + + + Sbjct: 552 LVGGNLKA--SEENLPQVDLNESVNELTEETSELLQKIELFTVERREVMEKMEQLKQENL 609 Query: 822 ELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQIL--LEENQNLQISLSDMQQHYNAL 879 L ++ + ++ V+ + +++ E ++L K + LEEN L ++ D+ + L Sbjct: 610 NLNMKIKEIENNRDVLAETYEQLQSEKEQLDAKLEKFGDLEENSRLNNAIIDLNRTLADL 669 Query: 880 VEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESA 939 + + + L + +K E++ L+ K EI L I+ ES Sbjct: 670 ENDNKSLQMKIEQLEESNNHLTEELEIVKNSESENRQLVESKGNEIVKL-IKEKENTESV 728 Query: 940 IRD-KKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQT 998 I + K + EK E+N +++T ++K NL + E N N E I ++ + Sbjct: 729 IENLHKTIREK-EENFQHIT------SDFKTKYLNLQKQLNE-NSSNFEAITAPLEAKIE 780 Query: 999 QSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLE 1058 + + + ++ K+ A LK+K + L K Q + + + + K+ Q E Sbjct: 781 ELTAKNKDQLEKMKKIAANLKKKTQACQDLEDKFKETQARHETSLQQLDEKIEQIKILEE 840 Query: 1059 NMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKL-TFEMNIPKTEGMIISS- 1116 E +++ + ++ ++ +L RE ++ TK+ EM + E ++ S Sbjct: 841 KNVELQNLITEMKVKNEVSLQQELLLTRENLGSVENSLRTKIQELEMIVETQESELVKSK 900 Query: 1117 -TIEPMSDDANNVDXXXXXXXXXXXXLKVQEE------EEFIQERSVLQEQSAKLNTELQ 1169 + + + + V+ L Q E EE + +L+++ L + Sbjct: 901 ERVNKLEEGLSFVEERRLSLERKANELGAQLEEKEITCEEMTRSEDLLEQRLVALAAHDE 960 Query: 1170 ECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNL---LSTVAELRSSISS 1226 K+ + N EL G + +E+ ++K K+E L + L T+ EL Sbjct: 961 AIERKLQEAIVENQELLGRNRELEEEGEKMKKKIEDLGEKFRQLEREKETIEELECENEK 1020 Query: 1227 AVDQ-RGFEIAELWKQH--LAQREADFQKTEHELRVQL-SAFESKYEQLLDSVQSSTQEE 1282 Q FE EL + + L + + DF K + ++Q F+ + E ++ + + + + Sbjct: 1021 LRKQVHDFE-NELKQTNDMLEESKNDFDKVNADWQLQFDEVFKERTELMIQCEKFAEELK 1079 Query: 1283 T---NKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVI---NQIEILRSEIEDEKVAFXX 1336 T + ++ + KL+ E +R +E+ + + E LR+ +++++V Sbjct: 1080 TIAEKEFGFNNELIEYKTKLEKSESEIREYEERIGQLTLEKEEFERLRNLLKEKEVELET 1139 Query: 1337 XXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVN 1396 + + + + S+ + + + K + + N Sbjct: 1140 KQSEIKQLIVEKDELRKLLSDKEPKPEANSLASFFDNVPEKKNEAQVETIPTFVWSGQTN 1199 Query: 1397 DAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKE 1456 D V + T + E + E+ +K L E E+ Q + + L YEK+ Sbjct: 1200 DPFDFVAQDT-KTENTNQELLEKIKTLEFMLYNTEKEKEDALHQCAQLTNELTQLVYEKQ 1258 Query: 1457 SELAILRLKMHENANHYETMQKESEIE 1483 + L+ + + +T ++ +IE Sbjct: 1259 MPIESQILQESDIKDTPDTCKQLEKIE 1285 Score = 214 bits (522), Expect = 2e-53 Identities = 375/1640 (22%), Positives = 698/1640 (42%), Gaps = 169/1640 (10%) Query: 56 RAQKCLENAALVSKRIKEHRKATAELLGRPFVPGISESLANTLKQKEILMEKIKQYKELS 115 RA+K +N A + I +K L R V LA K ++ + E + Q K Sbjct: 70 RAKKSSDNGAKKTLDIPASQKIN---LLRQQVEQNKVRLAERGKSQKGIEEMVTQLKAQL 126 Query: 116 KRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNALSVLQVKMKIMETTILDL 175 S I + + + L + K+ +S L K++ +ET +LDL Sbjct: 127 DDSQHLISQSPLNLSLQDPKIDYSENSNAQELYAVLLTKEKRISDLLAKVQKLETNVLDL 186 Query: 176 QEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDE 235 QE + EKD +I+A+ KA T ++TK+QM KMQENF+A+EAE K Sbjct: 187 QENLKEKDSVIDARTKAITLMTENLSRKGKNTLDTLDETKEQMRKMQENFVALEAEMKAR 246 Query: 236 KQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXL 295 + +LL+D+ K+ I+ L+E N LE E E +L + E Sbjct: 247 QMKLLEDLRLKNYEIAELQETNANLEKQISE-KAEDLELDLKTENSRLLDKIRELEVKLE 305 Query: 296 AKQSIEPSCEEKTEIEE--KGSLEI-----ANMTELTKKIELLEHLN------CQIRQTN 342 Q E + K ++EE K +++ + + ELTKKIE + ++ ++ N Sbjct: 306 ESQESEEVAKLKKQLEEANKNMIKVKAQHKSKVKELTKKIESFKKMSDANAEIVKLEAEN 365 Query: 343 KELENKLATMGTES-----KAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQD 397 L K+A + E K V S S KGS N E + ++ Sbjct: 366 SRLSQKIAELEEEKGSLQLKLVESDSNKGSETERENELENKIQ---------DHERMLEE 416 Query: 398 TDKKIN--KNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQ-L 454 DK I+ ++EI++ + I +LN+ L + K L+ + + + Sbjct: 417 KDKIISILESEISRSKTEIDNLNEKLNGQVKSEMVSIQFEEQLERVESEKRQLVEENERI 476 Query: 455 EHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAE----- 509 ++ G L + ++ E+A E QE N E+ D K EK+ SAE Sbjct: 477 CKEKEQLGEQLEQL---KKEKQEVATKLEHYIQE-NMELIDKLEKLSAEKVSSAESIEIV 532 Query: 510 EQITQLND-EIDAANKNMIKVKSNHKLKLKQMQKT--IDNFSKVSDSNKEIVR----LTE 562 E +TQ E++A +KN+ V N K + + + ++ +++++ E+++ T Sbjct: 533 ENLTQQEKLELEAYHKNLDLVGGNLKASEENLPQVDLNESVNELTEETSELLQKIELFTV 592 Query: 563 ELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQ 622 E + +K+ +L++E NL + + + ++ R + ++ Y+++ + + +L+ LE Sbjct: 593 ERREVMEKMEQLKQENLNLNMKIKEIENNRDVLAETYEQLQSEKEQLDAKLEKFGDLEEN 652 Query: 623 K------FDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSV-HLEEQIDALSASK 675 DL + L L+ ++ K+ + + ++ + E++ V + E + L SK Sbjct: 653 SRLNNAIIDLNRTLADLENDNKSLQMKIEQLEE-SNNHLTEELEIVKNSESENRQLVESK 711 Query: 676 -KELALVI---ENLKLDKEQLYGTIKDLENDKEDIMN-------KLQNYIQENMDLTDKL 724 E+ +I EN + E L+ TI++ E + + I + LQ + EN + + Sbjct: 712 GNEIVKLIKEKENTESVIENLHKTIREKEENFQHITSDFKTKYLNLQKQLNENSSNFEAI 771 Query: 725 EKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEES 784 KI EL AK N ++ K++ I A ++++ +++E K+K R E S Sbjct: 772 TAPLEAKIEELTAK-NKDQLEKMKK---IAANLKKKTQACQDLE---DKFKETQARHETS 824 Query: 785 IAVMEDRRYS---LERKADQLGSYLQEKQKAYSEYTIQEDELVNR--LAVLMDHDRVVEK 839 + ++++ LE K +L + + E K +E ++Q++ L+ R L + + R + Sbjct: 825 LQQLDEKIEQIKILEEKNVELQNLITE-MKVKNEVSLQQELLLTRENLGSVENSLRTKIQ 883 Query: 840 QL-LEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANR--TDLAESEST-K 895 +L + +E + EL K E L+ LS +++ +L KAN L E E T + Sbjct: 884 ELEMIVETQESELVKSK----ERVNKLEEGLSFVEERRLSLERKANELGAQLEEKEITCE 939 Query: 896 YQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIE 955 T+ DL H I +K +E I N ++ R+ + EK +K IE Sbjct: 940 EMTRSEDLLEQRLVALAAHDEAIERKLQE----AIVENQELLGRNRELEEEGEKMKKKIE 995 Query: 956 YVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLN 1015 + + QL+ K IE L E+L K ++ D + +QT D E+ N+ +K+N Sbjct: 996 DLGEKFRQLEREKETIEELECENEKLRK---QVHDFENELKQTN--DMLEESKNDFDKVN 1050 Query: 1016 ALLK-QKDE------EIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVS 1068 A + Q DE E++ +K + + ++L ++ TKLE E E++ Sbjct: 1051 ADWQLQFDEVFKERTELMIQCEKFAEELKTIAEKEFGFNNELIEYKTKLEKSESEIREYE 1110 Query: 1069 K---QLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDA 1125 + QL K+ E L+ L++E++ ++ E K++++ ++ + K E + S EP +A Sbjct: 1111 ERIGQLTLEKEEFERLRNLLKEKEVEL-ETKQSEIK-QLIVEKDELRKLLSDKEP-KPEA 1167 Query: 1126 NNVDXXXXXXXXXXXXLKVQEEEEFIQERSV-----LQEQSAKLNTELQECYTKIIQLET 1180 N++ +V+ F+ Q K QE KI LE Sbjct: 1168 NSLASFFDNVPEKKNEAQVETIPTFVWSGQTNDPFDFVAQDTKTENTNQELLEKIKTLEF 1227 Query: 1181 L--NTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQ-RGFEIAE 1237 + NTE D ++ Q QL ++L QL E + + S I D + E E Sbjct: 1228 MLYNTEKEKEDALH--QCAQLTNELTQLVYEKQMPIESQILQESDIKDTPDTCKQLEKIE 1285 Query: 1238 L--WKQHLAQREADFQKTEHELRVQ------------LSAFESKYEQLLDSV-QSSTQEE 1282 K L E ++V+ +S F + V + + Q+ Sbjct: 1286 FEPTKAPLVSSLEAGPVVEEPIQVKEAYLCYNDDSRNVSIFGENDDGWGCGVEEENVQKS 1345 Query: 1283 TNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXX 1342 T E++ L+ + ++ E +R LQ K A IE+L + ++ +++ Sbjct: 1346 TEHESLNERIRVLELERENHLEEIRQLQVKSAKEKQDIELLGWQQQNRELSAKLEQFEWG 1405 Query: 1343 XXXXXXXXD---LRTENQSY-KQMQE--QSILNINEENAQLKKSSXXXXXXXXXXXXRVN 1396 + T N+ K++QE ++I ++ +N +L+ Sbjct: 1406 DDSFTTEEKPTVVSTNNEDLAKKIQELNETIKDLTLDNEELQALLEEQRRLRIESEKTTV 1465 Query: 1397 DAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDE----FENVRQQLVEYEKRI--ED 1450 D E VL+ Q + E ++ E L ++NDE FE + QQ E ++ + +D Sbjct: 1466 DPE--VLKHLQQQLTTNCEEKKQLQEQINELIRKNDELSEKFETIEQQKAELDELVSSKD 1523 Query: 1451 LTYEK--------ESELAILRLKMHENANHYETMQK--ESEIERVKLIEELNVKITESVS 1500 T K E E+++L ++ E + E ++ E++ +R KL E+ K+ + Sbjct: 1524 ETIVKLNETLRGIEEEVSVLTTELQEKNSQIEALKTSFEAQDDREKLANEIEEKMATLKT 1583 Query: 1501 LNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSF 1560 + + L L+E+ + N ++ ++++Q I +L DE L N ++ + + +++ Sbjct: 1584 IESEKQLLFNELQEKNIQINTLRESVDSQ---IGSLKDE---LDNQIKIAQNLLEEKTLL 1637 Query: 1561 ASDTKQGRDE--QLDNTMNK 1578 + K+ E +L TM + Sbjct: 1638 SETLKEKESEVVRLSATMEQ 1657 Score = 175 bits (427), Expect = 6e-42 Identities = 313/1542 (20%), Positives = 649/1542 (42%), Gaps = 146/1542 (9%) Query: 144 VTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKI-------NEKDQIIEAKNKATTXX 196 + L+ T+ + +N LQ+K++ +E + L E++ +E Q++E+K Sbjct: 659 IIDLNRTLADLENDNKSLQMKIEQLEESNNHLTEELEIVKNSESENRQLVESKGNEIVKL 718 Query: 197 XXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEA 256 E+ + + + +ENF + +++K + L K + S+ E Sbjct: 719 IKEKENTESVI----ENLHKTIREKEENFQHITSDFKTKYLNLQKQLNENS---SNFEAI 771 Query: 257 NKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIE----- 311 LEA E++ ++ +++++ L + E +T ++ Sbjct: 772 TAPLEAKIEELTAKNKDQLEKMKKIAANLKKKTQACQDLEDKFKETQARHETSLQQLDEK 831 Query: 312 -------EKGSLEIANM-TELTKKIEL-LEHLNCQIRQTNKELENKLATMGTESKAV--- 359 E+ ++E+ N+ TE+ K E+ L+ R+ +EN L T E + + Sbjct: 832 IEQIKILEEKNVELQNLITEMKVKNEVSLQQELLLTRENLGSVENSLRTKIQELEMIVET 891 Query: 360 -SSPSKKGSPLISR-KSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSL 417 S K +++ + G + + + + ++E Q +K+I E+ + E +++ Sbjct: 892 QESELVKSKERVNKLEEGLSFVEERRLSLERKANELGAQLEEKEITCEEMTRSEDLLEQR 951 Query: 418 NKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHME--GPSLIHVGTNTEDV 475 L + I K G++ + + + ++ +E G + E + Sbjct: 952 LVALAAHDEAIERKLQEAIVENQELLGRNRELEEEGEKMKKKIEDLGEKFRQLEREKETI 1011 Query: 476 NEIAKVQEQLKQELND---EIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSN 532 E+ E+L+++++D E+K N D++E+ K+ +++ N + + K ++ Sbjct: 1012 EELECENEKLRKQVHDFENELKQTN--DMLEESKNDFDKV---NADWQLQFDEVFKERTE 1066 Query: 533 HKLKLKQMQKTIDNFS-KVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSG 591 ++ ++ + + + K N E++ +L ++ E EE G L L +++ Sbjct: 1067 LMIQCEKFAEELKTIAEKEFGFNNELIEYKTKLEKSESEIREYEERIGQLTLEKEEFERL 1126 Query: 592 RMI----ESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADI 647 R + E ++ K E++ L + + LL + + E + L +D V +K Sbjct: 1127 RNLLKEKEVELETKQSEIKQLIVEKDELRKLLSDK--EPKPEANSLASFFDNVPEKK--- 1181 Query: 648 SQLQSDQVCSEIKSVHLEEQIDALSASKKELAL---VIENLKLDKEQLYGTIKDLENDKE 704 ++ Q + + + + S + D ++ K ++E +K + LY T E +KE Sbjct: 1182 NEAQVETIPTFVWSGQTNDPFDFVAQDTKTENTNQELLEKIKTLEFMLYNT----EKEKE 1237 Query: 705 DIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYI 764 D +++ LT++L ++ EK + ++I E K D Q + Sbjct: 1238 DALHQCAQ-------LTNELTQLVYEKQMPIESQILQESDIKDTP----DTCKQLEKIEF 1286 Query: 765 ENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELV 824 E ++ L +EE I V E Y + S E + E+E V Sbjct: 1287 EPTKAPLVSSLEAGPVVEEPIQVKE--AYLCYNDDSRNVSIFGENDDGWGCGV--EEENV 1342 Query: 825 NRLAVLMDHDRVVEK-QLLEIEHENKELQKKNQILLEENQNLQ-ISLSDMQQHYNALVEK 882 + +H+ + E+ ++LE+E EN L++ Q+ ++ + Q I L QQ L K Sbjct: 1343 QKST---EHESLNERIRVLELEREN-HLEEIRQLQVKSAKEKQDIELLGWQQQNRELSAK 1398 Query: 883 ANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRD 942 + + + T + + + +N + + + Q L + I+DL ++ N ++++ + + Sbjct: 1399 LEQFEWGDDSFTT-EEKPTVVSTNNEDLAKKIQEL----NETIKDLTLD-NEELQALLEE 1452 Query: 943 KKVLNEKYEKNI---EYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKH--VQKQQ 997 ++ L + EK E + L+ QL + L + EL + N EL +K +++Q+ Sbjct: 1453 QRRLRIESEKTTVDPEVLKHLQQQLTTNCEEKKQLQEQINELIRKNDELSEKFETIEQQK 1512 Query: 998 TQSPDYTEQYINEINKLNALLKQKDEEIIALNQKIN--NAQVSYMSMVSDYESKLAQFTT 1055 + + I KLN L+ +EE+ L ++ N+Q+ + + + + Sbjct: 1513 AELDELVSSKDETIVKLNETLRGIEEEVSVLTTELQEKNSQIEALKTSFEAQDDREKLAN 1572 Query: 1056 KLENMEEEMQRVS--KQLLDSKQHNEELQI-LVREQ-DDQIKELKETKLTFEMNIPKTEG 1111 ++E ++ + KQLL ++ + +QI +RE D QI LK+ + I + Sbjct: 1573 EIEEKMATLKTIESEKQLLFNELQEKNIQINTLRESVDSQIGSLKDE---LDNQIKIAQN 1629 Query: 1112 MIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQEC 1171 ++ T+ +S+ + + QE + I +R +S KL+ E +E Sbjct: 1630 LLEEKTL--LSETLKEKESEVVRLSATMEQM-TQEWDLRIDQRGNDVAESWKLHLESRE- 1685 Query: 1172 YTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTV-AELRSSISSA--- 1227 +E T + + +++IN+L+ K L EN+ L V AE+R+ + Sbjct: 1686 -----------SEFTQIEQLLRKEINELEEKCNALVNENNELRKNVDAEIRNEVDRVAAL 1734 Query: 1228 ---VDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETN 1284 ++ R I EL K L +++ + + + EL + E E ++D V E + Sbjct: 1735 QQQINDRQQYINELTKT-LQEKQREVEGIQMELETTKQSLEIDKE-IVDGVLHLVVEFYD 1792 Query: 1285 KIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIED--EKVAFXXXXXXXX 1342 VT + SL L+D+E + L+ + + + E + E E V Sbjct: 1793 GGVTRDH--SLIKVLKDRENVIIGLKTELESLKTRFEDIEVEKTKGLEDVQRLRVMLEER 1850 Query: 1343 XXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKV 1402 +E Q+ K + +++ N+ + ++ + ++ + ++ Sbjct: 1851 EQTIAGLTSQVSELQNLKDYENENVQNLQQNLHDYQQINNNLSAQVQAQVAQIEAKDREL 1910 Query: 1403 LELTHQLELKDSE----IYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESE 1458 L H +E K E + T EY +T+ ++ E E ++++L E E R E+L + KES+ Sbjct: 1911 DNLRHLVEEKQRECDYAVENLTQEYRVTINEQVHEIEVLKRRLSENENRYEELLHSKESD 1970 Query: 1459 LAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAK 1518 L ++ ++++ + K EIE L +LN KI E SL +++ E EE + Sbjct: 1971 LEGVQYELNQ-----VMVSKSKEIEG--LASQLNTKIEECESLQRKIEEQ----VEETKQ 2019 Query: 1519 TNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNK 1578 E++ +E Q ++I L ++ N + +++ + + + + T + Sbjct: 2020 LTELRAIIEEQVLKIEELKKDLYEKSNDYDSLIAEMDISRTNVKAPEAAPPPKTEET--E 2077 Query: 1579 ELLDAVPRAELDLAMYMLHQRDVRCXXXXXXXXXXXXXRDTL 1620 +L + V RAELDLA+YMLHQRDVRC RDTL Sbjct: 2078 DLTEPVSRAELDLALYMLHQRDVRCEELTVELTQLLEERDTL 2119 Score = 107 bits (258), Expect = 2e-21 Identities = 177/836 (21%), Positives = 371/836 (44%), Gaps = 100/836 (11%) Query: 311 EEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLI 370 EEK ++ N +L KKI+ L + N+EL+ L E + + S+K + + Sbjct: 1412 EEKPTVVSTNNEDLAKKIQELNETIKDLTLDNEELQALL----EEQRRLRIESEKTT--V 1465 Query: 371 SRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISE 430 + ++ ++ + + + L + ++ I KN+ +L +++ + + + ++S Sbjct: 1466 DPEVLKHLQQQLTTNCEE--KKQLQEQINELIRKND--ELSEKFETIEQQKAELDELVSS 1521 Query: 431 KDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTED-----VNEI------A 479 KD G + ++ L E Q+ + +D NEI Sbjct: 1522 KDETIVKLNETLRGIEEEVSVLTTELQEKNSQIEALKTSFEAQDDREKLANEIEEKMATL 1581 Query: 480 KVQEQLKQELNDEIKDVNVKDLIEKLK-SAEEQITQLNDEIDAANKNMIKVKSNHKLKLK 538 K E KQ L +E+++ N++ I L+ S + QI L DE+D N IK+ N + Sbjct: 1582 KTIESEKQLLFNELQEKNIQ--INTLRESVDSQIGSLKDELD----NQIKIAQNLLEEKT 1635 Query: 539 QMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDV 598 + +T+ + E+VRL+ + ++Q+ +++GN D + + Sbjct: 1636 LLSETL------KEKESEVVRLSATMEQMTQEWDLRIDQRGN--------DVAESWKLHL 1681 Query: 599 YKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYD-EVEDKLADISQLQSDQVCS 657 + E + + K I+ LE + LV E + L++ D E+ +++ ++ LQ Q+ Sbjct: 1682 ESRESEFTQIEQLLRKEINELEEKCNALVNENNELRKNVDAEIRNEVDRVAALQ-QQIND 1740 Query: 658 EIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQEN 717 ++ I+ L+ + +E +E ++++ E T + LE DKE I++ + + + E Sbjct: 1741 R------QQYINELTKTLQEKQREVEGIQMELET---TKQSLEIDKE-IVDGVLHLVVEF 1790 Query: 718 MDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSR 777 D L K+ + ++ I G+ +++ E+IE E +K Sbjct: 1791 YD--------GGVTRDHSLIKVLKDRENVI---IGLKTELESLKTRFEDIEVEKTKGLED 1839 Query: 778 ICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQ--EDELVNRLAVLMDHDR 835 + RL ++E+R ++ Q+ S LQ K Y +Q + L + + + Sbjct: 1840 VQRLR---VMLEEREQTIAGLTSQV-SELQ-NLKDYENENVQNLQQNLHDYQQINNNLSA 1894 Query: 836 VVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALV-EKANRTD-----LA 889 V+ Q+ +IE +++EL ++ E+ + ++ ++ Q Y + E+ + + L+ Sbjct: 1895 QVQAQVAQIEAKDRELDNLRHLVEEKQRECDYAVENLTQEYRVTINEQVHEIEVLKRRLS 1954 Query: 890 ESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEK 949 E+E+ +Y+ L ES+L+ + +E ++V K KEIE L + NT+IE ++ + E+ Sbjct: 1955 ENEN-RYEELLHSKESDLEGVQYELNQVMVSKSKEIEGLASQLNTKIEECESLQRKIEEQ 2013 Query: 950 YEKNIEYVTQLEAQLQEYKNNIENLNMNV-EELNKMNLELIDKHVQKQQTQSPDYTEQYI 1008 E+ + +T+L A ++E IE L ++ E+ N + + + + + ++P+ Sbjct: 2014 VEET-KQLTELRAIIEEQVLKIEELKKDLYEKSNDYDSLIAEMDISRTNVKAPE------ 2066 Query: 1009 NEINKLNALLKQKDEEIIALNQKINNAQVSY-MSMVSDYESKLAQFTTKLENMEEEMQRV 1067 A K EE L + ++ A++ + M+ + + + T +L + EE + Sbjct: 2067 -------AAPPPKTEETEDLTEPVSRAELDLALYMLHQRDVRCEELTVELTQLLEERDTL 2119 Query: 1068 SKQLLDSKQHNEELQILVREQDDQIKELK-----ETKLTFEMNIPKTEGMIISSTI 1118 +L + + EEL V + ++ L E+ LT +++ KT G TI Sbjct: 2120 QLRLSNVLREKEELGRKVGGEGGSLEVLPKPVEVESSLTDKLSELKTVGYKKDKTI 2175 Score = 99 bits (238), Expect = 5e-19 Identities = 181/952 (19%), Positives = 392/952 (41%), Gaps = 65/952 (6%) Query: 628 QELHILQQKYDEVEDKLADI-SQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLK 686 ++ ++ Q+K DE + L+ ++ SD + + ++I+ L ++ + + Sbjct: 50 EQTNVTQEKVDEYMNTLSKRRAKKSSDNGAKKTLDIPASQKINLLRQQVEQNKVRLAERG 109 Query: 687 LDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTD-KLEKMSAEKISELLAKINHEEQS 745 ++ + + L+ +D + L + N+ L D K++ EL A + +E+ Sbjct: 110 KSQKGIEEMVTQLKAQLDDSQH-LISQSPLNLSLQDPKIDYSENSNAQELYAVLLTKEK- 167 Query: 746 KIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVM-EDRRYSLERKADQLGS 804 +I AK+Q+ + + +++ L + S I ++I +M E+ + D L Sbjct: 168 RISDLL---AKVQKLETNVLDLQENLKEKDSVIDARTKAITLMTENLSRKGKNTLDTLDE 224 Query: 805 YLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQN 864 ++ +K + E E+ R L++ R+ ++ E++ N L+K+ + E+ ++ Sbjct: 225 TKEQMRKMQENFVALEAEMKARQMKLLEDLRLKNYEIAELQETNANLEKQ---ISEKAED 281 Query: 865 LQISLSDMQQHYNALVEKANRTDLAESES------TKYQTQLRDLESNLKRITHEHQTLI 918 L++ D++ + L++K ++ ES K + QL + N+ ++ +H++ + Sbjct: 282 LEL---DLKTENSRLLDKIRELEVKLEESQESEEVAKLKKQLEEANKNMIKVKAQHKSKV 338 Query: 919 VQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNV 978 + K+IE + + E K E ++Q A+L+E K +++ L + Sbjct: 339 KELTKKIESFKKMSDANAEIV---------KLEAENSRLSQKIAELEEEKGSLQ-LKLVE 388 Query: 979 EELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVS 1038 + NK + + ++ + E+ I+ L + + + EI LN+K+N S Sbjct: 389 SDSNKGSETERENELENKIQDHERMLEEKDKIISILESEISRSKTEIDNLNEKLNGQVKS 448 Query: 1039 YMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKE- 1097 M + +E +L + ++ + EE +R+ K+ +Q E+L+ L +E+ + +L+ Sbjct: 449 EMVSIQ-FEEQLERVESEKRQLVEENERICKE---KEQLGEQLEQLKKEKQEVATKLEHY 504 Query: 1098 ----TKLTFEMNIPKTEGMIISSTIEPMSD--DANNVDXXXXXXXXXXXXLKVQEEEEFI 1151 +L ++ E + + +IE + + ++ ++ EE + Sbjct: 505 IQENMELIDKLEKLSAEKVSSAESIEIVENLTQQEKLELEAYHKNLDLVGGNLKASEENL 564 Query: 1152 QERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGH-DVVNQEQINQLKSKLEQLNTEN 1210 + L E +L E E KI E+ + + QE +N L K++++ Sbjct: 565 PQVD-LNESVNELTEETSELLQKIELFTVERREVMEKMEQLKQENLN-LNMKIKEIENNR 622 Query: 1211 DNLLSTVAELRSSISSAVDQRGFEIAELWKQ-HLAQREADFQKTEHELRVQLSAFESKYE 1269 D L T +L+S +D + + +L + L D +T +L + + K E Sbjct: 623 DVLAETYEQLQSE-KEQLDAKLEKFGDLEENSRLNNAIIDLNRTLADLENDNKSLQMKIE 681 Query: 1270 QLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIED 1329 QL +S T+E +IV + + Q E ++ ++EK + + IE L I + Sbjct: 682 QLEESNNHLTEEL--EIVKNSESENRQLVESKGNEIVKLIKEK-ENTESVIENLHKTIRE 738 Query: 1330 EKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQ---EQSILNINEENAQLKKSSXXXXX 1386 ++ F L + +++ + E I + +N + Sbjct: 739 KEENFQHITSDFKTKYLNLQKQLNENSSNFEAITAPLEAKIEELTAKNKDQLEKMKKIAA 798 Query: 1387 XXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFEN-VRQQLVEYE 1445 D E K E + E ++ +K + I L ++N E +N + + V+ E Sbjct: 799 NLKKKTQACQDLEDKFKETQARHETSLQQLDEKIEQIKI-LEEKNVELQNLITEMKVKNE 857 Query: 1446 KRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQV 1505 ++ L + + E + + E E VK E +N K+ E +S V Sbjct: 858 VSLQQELLLTRENLGSVENSLRTKIQELEMIVETQESELVKSKERVN-KLEEGLSF---V 913 Query: 1506 AELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKH 1557 E +LE K NE+ LE +EI +E+T ++++ + H Sbjct: 914 EERRLSLER---KANELGAQLEEKEITC----EEMTRSEDLLEQRLVALAAH 958 Score = 94.3 bits (224), Expect = 2e-17 Identities = 187/920 (20%), Positives = 402/920 (43%), Gaps = 114/920 (12%) Query: 715 QENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKY 774 QE DL D+ E+ I++L I EQ+ + + K+ E Y+ + +K Sbjct: 23 QELSDLKDQFEQQQV-LIAQLKEMIRKNEQTNVTQE-----KVDE---YMNTLSKRRAK- 72 Query: 775 KSRICRLEESIAVMEDRRYSLERK-ADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDH 833 KS ++++ + ++ +L R+ +Q L E+ K+ +E+V +L +D Sbjct: 73 KSSDNGAKKTLDIPASQKINLLRQQVEQNKVRLAERGKSQKGI----EEMVTQLKAQLDD 128 Query: 834 DRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESES 893 + L+ N LQ +I EN N Q + Y L+ K R ++ Sbjct: 129 SQ----HLISQSPLNLSLQDP-KIDYSENSNAQ-------ELYAVLLTKEKRISDLLAKV 176 Query: 894 TKYQTQLRDLESNLKRITHEHQTLIVQKKKEI----EDLEIEFNTQIESAIRDKKVLNEK 949 K +T + DL+ NLK E ++I + K I E+L + +++ K+ + + Sbjct: 177 QKLETNVLDLQENLK----EKDSVIDARTKAITLMTENLSRKGKNTLDTLDETKEQMRKM 232 Query: 950 YEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDY-TE--Q 1006 E + +++A+ + ++ N + EL + N L + +K + D TE + Sbjct: 233 QENFVALEAEMKARQMKLLEDLRLKNYEIAELQETNANLEKQISEKAEDLELDLKTENSR 292 Query: 1007 YINEINKLNALLK--QKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEM 1064 +++I +L L+ Q+ EE+ L +++ A + + + + ++SK+ + T K+E+ ++ M Sbjct: 293 LLDKIRELEVKLEESQESEEVAKLKKQLEEANKNMIKVKAQHKSKVKELTKKIESFKK-M 351 Query: 1065 QRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDD 1124 + +++ + N L +I EL+E K + ++ + +++ S T E ++ Sbjct: 352 SDANAEIVKLEAENSRLS-------QKIAELEEEKGSLQLKLVESDSNKGSET-ERENEL 403 Query: 1125 ANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKII---QLETL 1181 N + + + E E + ++ + + KLN +++ I QLE + Sbjct: 404 ENKIQDHERMLEEKDKIISILESE-ISRSKTEIDNLNEKLNGQVKSEMVSIQFEEQLERV 462 Query: 1182 NTELTGHDVVNQ----------EQINQLKSKLEQLNTENDNLLSTVAEL-----RSSISS 1226 +E N+ EQ+ QLK + +++ T+ ++ + EL + S Sbjct: 463 ESEKRQLVEENERICKEKEQLGEQLEQLKKEKQEVATKLEHYIQENMELIDKLEKLSAEK 522 Query: 1227 AVDQRGFEIAE-LWKQHLAQREADFQKTEHELRVQLSAFESKYEQ--LLDSVQSSTQEET 1283 EI E L +Q + EA + K + L A E Q L +SV T+E + Sbjct: 523 VSSAESIEIVENLTQQEKLELEA-YHKNLDLVGGNLKASEENLPQVDLNESVNELTEETS 581 Query: 1284 NKIVTMEQVTSLQNKLQDKEEHLR----NLQEKYADVINQIEILRSEIEDEKVAFXXXXX 1339 + +E T + ++ +K E L+ NL K ++ N ++L E + Sbjct: 582 ELLQKIELFTVERREVMEKMEQLKQENLNLNMKIKEIENNRDVLAETYEQLQ-------- 633 Query: 1340 XXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAE 1399 L + + + ++E S +N L ++ ++ E Sbjct: 634 -------SEKEQLDAKLEKFGDLEENS--RLNNAIIDLNRTLADLENDNKSLQMKIEQLE 684 Query: 1400 AKVLELTHQLEL-KDSE------IYQKTHEYTITLTQR-NDE--FENVRQQLVEYEKRIE 1449 LT +LE+ K+SE + K +E + ++ N E EN+ + + E E+ + Sbjct: 685 ESNNHLTEELEIVKNSESENRQLVESKGNEIVKLIKEKENTESVIENLHKTIREKEENFQ 744 Query: 1450 DLTYEKESELAILRLKMHENANHYE--TMQKESEIERVKLIEELNVKITESVSLN-KQVA 1506 +T + +++ L+ +++EN++++E T E++IE + + ++ + ++ N K+ Sbjct: 745 HITSDFKTKYLNLQKQLNENSSNFEAITAPLEAKIEELTAKNKDQLEKMKKIAANLKKKT 804 Query: 1507 ELNKALEEEVAKTN-EMQTALE--NQEIE-IVTLNDEITNLQNMVRASSSKIQKHVSFAS 1562 + + LE++ +T +T+L+ +++IE I L ++ LQN++ + K++ VS Sbjct: 805 QACQDLEDKFKETQARHETSLQQLDEKIEQIKILEEKNVELQNLI--TEMKVKNEVSLQQ 862 Query: 1563 DTKQGRDE--QLDNTMNKEL 1580 + R+ ++N++ ++ Sbjct: 863 ELLLTRENLGSVENSLRTKI 882 Score = 66.5 bits (155), Expect = 6e-09 Identities = 135/684 (19%), Positives = 290/684 (42%), Gaps = 52/684 (7%) Query: 297 KQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTES 356 +Q + +CEEK +++E+ + I EL++K E +E ++ + + + + Sbjct: 1474 QQQLTTNCEEKKQLQEQINELIRKNDELSEKFETIEQQKAELDELVSSKDETIVKLNETL 1533 Query: 357 KAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQS 416 + + + + K+ + A K +Q E L + ++K+ + +E Q Sbjct: 1534 RGIEEEVSVLTTELQEKNSQIEALKTSFE-AQDDREKLANEIEEKMAT--LKTIESEKQL 1590 Query: 417 LNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIH--VGTNTED 474 L +L +K I+ KD L Q+++ Q +E +L+ + + Sbjct: 1591 LFNELQEKNIQINTLRESVDSQIGSL--KDELDNQIKIA-QNLLEEKTLLSETLKEKESE 1647 Query: 475 VNEIAKVQEQLKQELNDEIKDVNVKDLIEK----LKSAEEQITQ----LNDEI-DAANKN 525 V ++ EQ+ QE + I D D+ E L+S E + TQ L EI + K Sbjct: 1648 VVRLSATMEQMTQEWDLRI-DQRGNDVAESWKLHLESRESEFTQIEQLLRKEINELEEKC 1706 Query: 526 MIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHL 585 V N++L+ + + +V+ ++I + ++ L++ + E + E +Q+ L Sbjct: 1707 NALVNENNELRKNVDAEIRNEVDRVAALQQQINDRQQYINELTKTLQEKQREVEGIQMEL 1766 Query: 586 VDYDSGRMIESD----VYKKMIEMENLAETR----LKAISLLESQKFDLVQELHILQQKY 637 I+ + V ++E + TR +K + E+ L EL L+ ++ Sbjct: 1767 ETTKQSLEIDKEIVDGVLHLVVEFYDGGVTRDHSLIKVLKDRENVIIGLKTELESLKTRF 1826 Query: 638 DEVE-DKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTI 696 +++E +K + +Q +V E + E+ I L++ EL +NLK + + + Sbjct: 1827 EDIEVEKTKGLEDVQRLRVMLEER----EQTIAGLTSQVSEL----QNLKDYENENVQNL 1878 Query: 697 KDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQ--TQFGID 754 + +D + I N L +Q + + ++ + + L+ + E ++ TQ Sbjct: 1879 QQNLHDYQQINNNLSAQVQAQVAQIEAKDR-ELDNLRHLVEEKQRECDYAVENLTQ-EYR 1936 Query: 755 AKIQERDLYIENIESELSKYKSRICRLEESI-AVMEDRRYSLE-------RKADQLGSYL 806 I E+ IE ++ LS+ ++R L S + +E +Y L ++ + L S L Sbjct: 1937 VTINEQVHEIEVLKRRLSENENRYEELLHSKESDLEGVQYELNQVMVSKSKEIEGLASQL 1996 Query: 807 QEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQ 866 K + + +E V L + ++E+Q+L+IE K+L +K+ + Sbjct: 1997 NTKIEECESLQRKIEEQVEETKQLTELRAIIEEQVLKIEELKKDLYEKSNDYDSLIAEMD 2056 Query: 867 ISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTL-IVQKKKEI 925 IS ++++ A K T+ ++ + L + + + E T+ + Q +E Sbjct: 2057 ISRTNVKAPEAAPPPKTEETEDLTEPVSRAELDLALYMLHQRDVRCEELTVELTQLLEER 2116 Query: 926 EDLEIEFNTQIESAIRDKKVLNEK 949 + L++ ++ + +R+K+ L K Sbjct: 2117 DTLQL----RLSNVLREKEELGRK 2136 >UniRef50_Q171W5 Cluster: Lava lamp protein; n=2; Culicidae|Rep: Lava lamp protein - Aedes aegypti (Yellowfever mosquito) Length = 3407 Score = 236 bits (578), Expect = 3e-60 Identities = 304/1382 (21%), Positives = 613/1382 (44%), Gaps = 135/1382 (9%) Query: 221 MQENFIAMEAEWKDEKQRLLKDIESKDVRIS-SLEEANKLLEAARFEISLEHSKLAQELE 279 +++ A E++ EK +++ +E K + + +L+E ++EA +SL L+ + + Sbjct: 238 LEQELAAKESQRVPEKDEVVQGLERKILDLEEALKEKECVIEARTQAVSLMSENLSLKGK 297 Query: 280 QXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIR 339 + ++ K E++ L++ + E KI LE +N + Sbjct: 298 NTVDLLEDTKQEMYRMQSNFVQAESNMKAELDR---LQV-ELDERKSKISNLEEMNNILE 353 Query: 340 QTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTD 399 +L + A++ + + V S K S L K ++ ++ ++L S+ TD Sbjct: 354 TARYDLTVENASLKQKLEDVQDFSTKISEL--NKLNQSLQHRI----TELESQKYEFITD 407 Query: 400 KKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQH 459 + + + + Q L + + E +S K + I + E + + Sbjct: 408 AEAEQAKFGASDEKYQELLDRIHELEEELSRKAAPQEDLLEKIRSLEATIQAQKEEIETY 467 Query: 460 MEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQI--TQLND 517 + + + N ++ V L +++K+ K L K E ++ ++L Sbjct: 468 NQQQAELQ--ENLQEKTVELNVLNANFSVLQEKLKNAGPKPLFPKSAEEEAEVENSKLKQ 525 Query: 518 EIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEE 577 ++D ANK+MIK KLK+KQ+QK +D+F K S ++E+VRLT+E+ L+Q++AE+EEE Sbjct: 526 QLDEANKSMIK----SKLKIKQLQKQVDSFKKTSAVHEEVVRLTDEVQTLTQRLAEVEEE 581 Query: 578 KGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKY 637 KGNLQLHLV+YD G + +S++ K++ +E + + AI LLE QK D+ ++L+ + + Sbjct: 582 KGNLQLHLVNYD-GSLPDSELEKRIKILETTCQNQTTAIQLLEEQKIDMTEDLNSTKTQL 640 Query: 638 DEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIK 697 + + D++ + Q Q+DQ + I D +S+ + E L E D+++L + Sbjct: 641 ERMRDQVKE-HQDQADQSGTVIS--------DHMSSIETEEQL--EKCVADRDRLVEQVH 689 Query: 698 DLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKIS-----ELLAKINHEEQSKIQT--- 749 LE ++ ++ KL Y+ ENM+L DK+EK+S EK+S E++ + +E+ +I++ Sbjct: 690 QLEEERSELQQKLDRYVVENMELLDKIEKLSLEKVSSAESIEIVEGLTAKEKQEIESFEK 749 Query: 750 ----------QFGIDAKIQERDLYIENIESE--LSKYKSRICRLEESIAVMEDRRYSLER 797 G+D ++R E+ + + L + R + ED + Sbjct: 750 ACRKQQLAEPPGGVDEVDRDRPSNDEDDDDDGPLQVHSERRDEPTTGDSEGEDPNSCQAK 809 Query: 798 KADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQI 857 + ++ S L K + +T + E++ +L L ++ +L ++ E++EL +K+ Sbjct: 810 QREEQHSELMHKIEL---FTNERREVLEKLEALTVENQTHIDELDQLREEHQELVQKHVA 866 Query: 858 LLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTL 917 L + Q L+ SL+ +Q +LVE+ + A++ K +++ S+ + + Sbjct: 867 LEKVEQELKASLTKTEQEKASLVEE---LEAAKTLKAKLESEASSTPSSSQSTPSKAAAS 923 Query: 918 IVQK---KKEIEDLEIEFNTQIESAIRDKKV-LNEKYEKNIEYVTQL-EAQLQEYKNNI- 971 ++ K ++ + ++ E ++ + KK+ +++K + + + ++ + L+EY N+ Sbjct: 924 VIDKDSFEQALRSVDNEVTNYNKNKDKTKKLQISKKLSSDAKNLQKMANSLLEEYYRNLA 983 Query: 972 --ENLNMNVEELNK--MNLELIDK--HVQKQQTQSPDYTEQYINEINKLNAL---LKQKD 1022 E + M +E+L L +D+ + + Q + T I+++++++ L L++K+ Sbjct: 984 ECEAMKMEIEQLKDKVQRLPEVDRTEEINGLKAQIMEMTHAQIDKVDQIDQLREDLERKN 1043 Query: 1023 EEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQ 1082 EEI L +++ A+ + S SD E +L + N E + +LL K+ E Sbjct: 1044 EEIGELKREMEAAREAEKS--SDEEPELLKVELNSRNDEIRELKKELELLGVKKAGE--- 1098 Query: 1083 ILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXL 1142 + Q + KE ++ E+ + + + IE + N + Sbjct: 1099 -IEEAQAKLVAATKEIEILKELVAEQKQQL-----IETYQEHENEIAG------------ 1140 Query: 1143 KVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSK 1202 K++E +++ + + +Q LN +L E K + ++ + Q+Q ++++ K Sbjct: 1141 KLKEIQDYENQAQKMADQVEDLNRQLVEVGEK--YSNDMKRQVEELKSLTQKQSDEIEHK 1198 Query: 1203 LEQLNTENDNLL---STVAELRSSISSAVDQRGF--EIAELWK---QHLAQREADFQKTE 1254 E ++T N+ ++ TV + + I D+ + E+ E K Q L ++ KT Sbjct: 1199 QETIDTLNNQIIELYKTVEDNANKIIEKEDEVQYLQELLESKKDEIQMLYEKLTVANKTA 1258 Query: 1255 HELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYA 1314 +LR +L +K ++D Q E+ N + + L KL+ +L+ + Sbjct: 1259 EDLRAKLEEALAKPVPVVDEAQIKDLEQKNHDLDAKN-KELLEKLKKFAANLKKKNVQCQ 1317 Query: 1315 DVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEEN 1374 ++ ++ L+ E+E+ + DL+ EN+ Q ++N E Sbjct: 1318 ELEGKLASLQQELEELR---------KSAAAGMSVDDLKEENEQLSQKMH----HLNNEL 1364 Query: 1375 AQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEF 1434 +L + + + +V +E E+ +K E L ++ E Sbjct: 1365 HKLLQLKYNLETEKQAAQHETLELKERV----QAMEANVKELEEKRQEVESQLAEQQKEL 1420 Query: 1435 ENVRQQLVEYEKRIEDL-TYEKESELAILRLKMHENANHY---ETMQKESEIE----RVK 1486 E VR +IE KE I RL+ HE Y E +S++E + Sbjct: 1421 ETVRNDDASKNVKIEKCKAIIKEKNKEIQRLQEHERKTSYLQDEIKMAQSKLEDFHNQTM 1480 Query: 1487 LIEELNVKITESVSLNKQVAELNKALEEEVA----KTNEMQTALENQEIEIVTLNDEITN 1542 L+ L E + K E +ALEEEV K +++ LE E E L +I Sbjct: 1481 LLGRLKADKEELNAEMKIQVERCQALEEEVCQGAEKMRKLEVDLEISEEENKKLKSKIVK 1540 Query: 1543 LQ 1544 L+ Sbjct: 1541 LE 1542 Score = 193 bits (471), Expect = 3e-47 Identities = 278/1360 (20%), Positives = 577/1360 (42%), Gaps = 114/1360 (8%) Query: 234 DEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXX 293 D+ +L +D+E K+ I L+ +EAAR E K + E + Sbjct: 1030 DQIDQLREDLERKNEEIGELKRE---MEAAR-----EAEKSSDEEPELLKVELNSRNDEI 1081 Query: 294 XLAKQSIEPSCEEKT-EIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATM 352 K+ +E +K EIEE + +A E+ EL+ Q+ +T +E EN++A Sbjct: 1082 RELKKELELLGVKKAGEIEEAQAKLVAATKEIEILKELVAEQKQQLIETYQEHENEIAGK 1141 Query: 353 GTESKAVSSPSKKGSPLISRKS------GRNTASKMKSPWSQLSSETLNQDTDKKINKNE 406 E + + ++K + + + G ++ MK +L S T Q + + + Sbjct: 1142 LKEIQDYENQAQKMADQVEDLNRQLVEVGEKYSNDMKRQVEELKSLTQKQSDEIEHKQET 1201 Query: 407 IAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLI 466 I L I L K + D I EK+ K ++Q+ +++ L Sbjct: 1202 IDTLNNQIIELYKTVEDNANKIIEKEDEVQYLQELLESKKD---EIQMLYEK------LT 1252 Query: 467 HVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEID--AANK 524 ED+ AK++E L + + + + +KDL +K + + +L +++ AAN Sbjct: 1253 VANKTAEDLR--AKLEEALAKPV-PVVDEAQIKDLEQKNHDLDAKNKELLEKLKKFAANL 1309 Query: 525 NMIKVKSNH-KLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQL 583 V+ + KL +Q+ ++ K + + + L EE LSQK+ L E L Sbjct: 1310 KKKNVQCQELEGKLASLQQELEELRKSAAAGMSVDDLKEENEQLSQKMHHLNNE-----L 1364 Query: 584 HLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDK 643 H K+++++ ET +A + + +L + + ++ E+E+K Sbjct: 1365 H----------------KLLQLKYNLETEKQAA---QHETLELKERVQAMEANVKELEEK 1405 Query: 644 LADI-SQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKD-LEN 701 ++ SQL Q E+++V ++ + K + + +N ++ + Q + L++ Sbjct: 1406 RQEVESQLAEQQ--KELETVRNDDASKNVKIEKCKAIIKEKNKEIQRLQEHERKTSYLQD 1463 Query: 702 DKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERD 761 + + +KL+++ + M L +L+ E +E+ ++ + + + G + K+++ + Sbjct: 1464 EIKMAQSKLEDFHNQTM-LLGRLKADKEELNAEMKIQVERCQALEEEVCQGAE-KMRKLE 1521 Query: 762 LYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQED 821 + +E E E K KS+I +LE+ I+++E+RR SLER+ LG L EKQ+ + ++ ED Sbjct: 1522 VDLEISEEENKKLKSKIVKLEQGISLVEERRNSLERQKKLLGDKLDEKQQEFIQH---ED 1578 Query: 822 ELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVE 881 EL+ RLA L HD VE +L E E E EL K + + + LQ L+ ++ A E Sbjct: 1579 ELMQRLANLSQHDEAVEGKLKEKEEELLELGSKLRDVEYQRDQLQSKLNQLEAQIGAFEE 1638 Query: 882 KANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIR 941 + R E+E+ ++ L++ +KR+ E + +++K EI+ LE E Q+ Sbjct: 1639 SSKRASELENENYNLTQEVAALQAEVKRVLAESEAKVLEKDSEIDQLEYELTNQLSKIED 1698 Query: 942 DKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMN--LELIDKHVQKQQTQ 999 ++K L E E+ + + L+ ++ + N+ +L +L K L++ ++ + + Sbjct: 1699 ERKQLQENLERTRDSNSDLQDEVVRLQENVNSLEQQRTDLEKETTWLKMQNESLNHDSNE 1758 Query: 1000 SPDYTEQYINEINKLNALLKQKDE-------EIIALNQKINNAQVSYMSMVSDYESKLAQ 1052 + Q + + +L L Q D EI AL Q+I + + + + Sbjct: 1759 LQELRMQIVQDQTELENLRAQCDTLAQNHQYEINALKQQIADMEAIRTQLSQNQTDDQVS 1818 Query: 1053 FTTKLENMEEEMQRVSKQLLDSKQHNEELQILVR--EQDDQIKELKET--KLTFEMNIPK 1108 ++ ++E + + ++ +Q N ++Q+ + +D L+ T + T + K Sbjct: 1819 VQNEVTKLKERLDKKEAEVAQLQQKNLQMQMTASGGQVEDPFSSLQATPERSTAALE-EK 1877 Query: 1109 TEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTEL 1168 + +T + ++ ++Q ++ +Q L+ Q A+ ++EL Sbjct: 1878 IRELENDATWKDSRIQELQIEKDLADGSLEELRKQLQMLQQNVQNSEALEAQLAQKSSEL 1937 Query: 1169 QECYTKIIQLETLNTELTGHDVVNQEQINQL------KSKLEQLNTENDNL-LSTVAELR 1221 ++ ++ Q + + + +Q S + +T + ++ Sbjct: 1938 EQLSKQLFQTVPAKKPVQEVEAIPTFSTSQFFAAPSESSAVTLFDTAGEGWGWDEPVAVQ 1997 Query: 1222 SSISSAVDQRGFEIAELWK--QHLAQREADFQKTEHELRVQLSAF---ESKYEQLLDSVQ 1276 ++++ ++ E+ L + L R K EL+ +L +S+Y+QL D V Sbjct: 1998 QQVATSASEQSNELQMLRDEIEQLKARNEAAAKEVQELQGRLGTVVDRDSEYQQLKDEVD 2057 Query: 1277 SSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXX 1336 + + ++V KL+ + L Q K + + Q+ S + V+ Sbjct: 2058 ILRSQNAS---LNQEVDEKAAKLRSVAQSLLEEQVKVSQLEEQLHSNESAVVAPSVS--- 2111 Query: 1337 XXXXXXXXXXXXXXDLRTENQSY----KQMQEQSILNINEENAQLKKSSXXXXXXXXXXX 1392 DL ++Y +E+ ++ EE A + S+ Sbjct: 2112 SFFADSASQGPVFEDLIVPKKAYMCTPSASEEREEWSV-EEPAVV--STAATSQHAVGFM 2168 Query: 1393 XRVNDAEAKVLELTHQLELKD-SEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDL 1451 +V+D E + L +L+LK E +K E T E ++Q L + ++R +L Sbjct: 2169 SKVDDRELENLREQSELQLKQIREQDEKLRESGQQYTTVQSTVERLQQDLSQLQQRYAEL 2228 Query: 1452 TYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKA 1511 +S +A + ++ E E ++L +E+++ L Q A L+ Sbjct: 2229 EAHLQSTIASHQTEVEGKM----AALAEQNDEFLQLKDEIDI-------LRAQNASLSYE 2277 Query: 1512 LEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASS 1551 L+E AK + +L+ +++++ L +++ + ++ V A S Sbjct: 2278 LDEATAKLKNLAQSLQEEQLKVCQLEEQLHSKESAVAAPS 2317 Score = 175 bits (426), Expect = 8e-42 Identities = 296/1499 (19%), Positives = 629/1499 (41%), Gaps = 139/1499 (9%) Query: 168 METTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIA 227 +E ILDL+E + EK+ +IEA+ +A + EDTKQ+M +MQ NF+ Sbjct: 260 LERKILDLEEALKEKECVIEARTQAVSLMSENLSLKGKNTVDLLEDTKQEMYRMQSNFVQ 319 Query: 228 MEAEWKDEKQRLLKDIESKDVRISSLEEANKLL---------EAARFEISLEHSK-LAQE 277 E+ K E RL +++ + +IS+LEE N +L E A + LE + + + Sbjct: 320 AESNMKAELDRLQVELDERKSKISNLEEMNNILETARYDLTVENASLKQKLEDVQDFSTK 379 Query: 278 LEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQ 337 + + L Q E + + E + G+ + EL +I LE + Sbjct: 380 ISELNKLNQSLQHRITELESQKYEFITDAEAEQAKFGASD-EKYQELLDRIHELEEELSR 438 Query: 338 IRQTNKELENKL----ATMGTESKAVSSPSKKGSPLISRKSGRNTA-SKMKSPWSQLSSE 392 ++L K+ AT+ + + + + +++ + L + + + + +S L + Sbjct: 439 KAAPQEDLLEKIRSLEATIQAQKEEIETYNQQQAELQENLQEKTVELNVLNANFSVLQEK 498 Query: 393 TLNQDTDKKINKN-------EIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGK 445 N K+ E +KL+ + NK ++ + I + Sbjct: 499 LKNAGPKPLFPKSAEEEAEVENSKLKQQLDEANKSMIKSKLKIKQLQKQVDSFKKTSAVH 558 Query: 446 DTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIK--DVNVKDLIE 503 + ++ +L E Q + + + ++ + EL IK + ++ Sbjct: 559 EEVV-RLTDEVQTLTQRLAEVEEEKGNLQLHLVNYDGSLPDSELEKRIKILETTCQNQTT 617 Query: 504 KLKSAEEQITQLNDEIDAANKNMIKVKSN---HKLKLKQMQKTIDNFSKVSDSNKEIVRL 560 ++ EEQ + +++++ + +++ H+ + Q I + ++ +++ + Sbjct: 618 AIQLLEEQKIDMTEDLNSTKTQLERMRDQVKEHQDQADQSGTVISDHMSSIETEEQLEKC 677 Query: 561 TEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLE 620 + L ++V +LEEE+ LQ L Y V + M ++ + + L+ +S E Sbjct: 678 VADRDRLVEQVHQLEEERSELQQKLDRY---------VVENMELLDKIEKLSLEKVSSAE 728 Query: 621 SQKFDLVQELHILQQKYDEVEDKLADISQLQS-----DQVCSEIKSVHLEEQIDA---LS 672 S ++V+ L +++ E +K QL D+V + S ++ D + Sbjct: 729 S--IEIVEGLTAKEKQEIESFEKACRKQQLAEPPGGVDEVDRDRPSNDEDDDDDGPLQVH 786 Query: 673 ASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKI 732 + +++ ++ D K E ++M+K++ + E ++ +KLE ++ E Sbjct: 787 SERRDEPTTGDSEGEDPNSCQA--KQREEQHSELMHKIELFTNERREVLEKLEALTVENQ 844 Query: 733 SEL--LAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMED 790 + + L ++ E Q +Q ++ QE +++ L+K + L E + + Sbjct: 845 THIDELDQLREEHQELVQKHVALEKVEQE-------LKASLTKTEQEKASLVEELEAAKT 897 Query: 791 RRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKE 850 + LE +A S Q + I +D L R V+ ++ ++NK+ Sbjct: 898 LKAKLESEASSTPSSSQSTPSKAAASVIDKDSFEQAL-------RSVDNEVTNY-NKNKD 949 Query: 851 LQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQT-QLRDLESNLKR 909 KK QI ++ L ++Q+ N+L+E+ R +LAE E+ K + QL+D L Sbjct: 950 KTKKLQI----SKKLSSDAKNLQKMANSLLEEYYR-NLAECEAMKMEIEQLKDKVQRLPE 1004 Query: 910 I--THEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKY---EKNIEYVTQLEAQL 964 + T E L Q E+ +I+ QI+ D + NE+ ++ +E + E Sbjct: 1005 VDRTEEINGLKAQIM-EMTHAQIDKVDQIDQLREDLERKNEEIGELKREMEAAREAEKSS 1063 Query: 965 QE----YKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQ 1020 E K + + N + EL K LEL+ + ++ EI L L+ + Sbjct: 1064 DEEPELLKVELNSRNDEIRELKK-ELELLGVKKAGEIEEAQAKLVAATKEIEILKELVAE 1122 Query: 1021 KDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLL-DSKQHNE 1079 + +++I Q+ N + + DYE++ + ++E++ ++ V ++ D K+ E Sbjct: 1123 QKQQLIETYQEHENEIAGKLKEIQDYENQAQKMADQVEDLNRQLVEVGEKYSNDMKRQVE 1182 Query: 1080 ELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXX 1139 EL+ L ++Q D+I+ +ET T I + + T+E D+AN + Sbjct: 1183 ELKSLTQKQSDEIEHKQETIDTLNNQIIE-----LYKTVE---DNANKIIEKEDEVQYLQ 1234 Query: 1140 XXLKVQEEE-EFIQERSVLQEQSAK-LNTELQECYTKII------QLETLNTELTGHDVV 1191 L+ +++E + + E+ + ++A+ L +L+E K + Q++ L + D Sbjct: 1235 ELLESKKDEIQMLYEKLTVANKTAEDLRAKLEEALAKPVPVVDEAQIKDLEQKNHDLDAK 1294 Query: 1192 NQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQ 1251 N+E + +LK L +N EL ++S E+ EL K A D Sbjct: 1295 NKELLEKLKKFAANLKKKNVQC----QELEGKLASLQQ----ELEELRKSAAAGMSVDDL 1346 Query: 1252 KTEHE-LRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQ 1310 K E+E L ++ ++ +LL Q ET K + L+ ++Q E +++ L+ Sbjct: 1347 KEENEQLSQKMHHLNNELHKLL---QLKYNLETEKQAAQHETLELKERVQAMEANVKELE 1403 Query: 1311 EKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQE-QSILN 1369 EK +V +Q+ + E+E + ++ +N+ +++QE + + Sbjct: 1404 EKRQEVESQLAEQQKELETVR----NDDASKNVKIEKCKAIIKEKNKEIQRLQEHERKTS 1459 Query: 1370 INEENAQLKKSSXXXXXXXXXXXXRVN------DAEAKV-LELTHQLELKDSEIYQKTHE 1422 ++ ++ +S R+ +AE K+ +E LE + + +K + Sbjct: 1460 YLQDEIKMAQSKLEDFHNQTMLLGRLKADKEELNAEMKIQVERCQALEEEVCQGAEKMRK 1519 Query: 1423 YTITLTQRNDEFENVRQQLVEYEKRI---EDLTYEKESELAILRLKMHENANHY-----E 1474 + L +E + ++ ++V+ E+ I E+ E + +L K+ E + E Sbjct: 1520 LEVDLEISEEENKKLKSKIVKLEQGISLVEERRNSLERQKKLLGDKLDEKQQEFIQHEDE 1579 Query: 1475 TMQKESEI-ERVKLIE-ELNVKITESVSLNKQVAELNKALEEEVAKTNEMQT---ALENQ 1529 MQ+ + + + + +E +L K E + L ++ ++ ++ +K N+++ A E Sbjct: 1580 LMQRLANLSQHDEAVEGKLKEKEEELLELGSKLRDVEYQRDQLQSKLNQLEAQIGAFEES 1639 Query: 1530 EIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAE 1588 L +E NL V A +++++ ++ + +D ++D + EL + + + E Sbjct: 1640 SKRASELENENYNLTQEVAALQAEVKRVLAESEAKVLEKDSEIDQ-LEYELTNQLSKIE 1697 Score = 130 bits (315), Expect = 2e-28 Identities = 214/1051 (20%), Positives = 462/1051 (43%), Gaps = 87/1051 (8%) Query: 306 EKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKK 365 EK E E K SL TE +K L+E L + +LE++ ++ T S + S+PSK Sbjct: 868 EKVEQELKASL---TKTE-QEKASLVEELEAA-KTLKAKLESEASS--TPSSSQSTPSKA 920 Query: 366 GSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKIN-KNEIAKLEMVIQSLNKDLVDK 424 + +I + S ++S +++++ N+D KK+ +++ +Q + L+++ Sbjct: 921 AASVIDKDSFEQA---LRSVDNEVTNYNKNKDKTKKLQISKKLSSDAKNLQKMANSLLEE 977 Query: 425 EYV-ISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQE 483 Y ++E + L + E ++ + + V++I +++E Sbjct: 978 YYRNLAECEAMKMEIEQLKDKVQRLPEVDRTEEINGLKAQIMEMTHAQIDKVDQIDQLRE 1037 Query: 484 QLKQELNDEIKDVN--VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQ 541 L+++ N+EI ++ ++ E KS++E+ L E+++ N + ++K +L+L ++ Sbjct: 1038 DLERK-NEEIGELKREMEAAREAEKSSDEEPELLKVELNSRNDEIRELKK--ELELLGVK 1094 Query: 542 KTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKK 601 K ++ ++ ++V T+E+ L + VAE +++ L++ + + E+++ K Sbjct: 1095 KA----GEIEEAQAKLVAATKEIEILKELVAEQKQQ-------LIE--TYQEHENEIAGK 1141 Query: 602 MIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKS 661 + E+++ K +E LV+ ++L ++Q QSD++ Sbjct: 1142 LKEIQDYENQAQKMADQVEDLNRQLVEVGEKYSNDMKRQVEELKSLTQKQSDEI------ 1195 Query: 662 VHLEEQIDALSASKKELALVIE---NLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENM 718 H +E ID L+ EL +E N ++KE +++L K+D + L E + Sbjct: 1196 EHKQETIDTLNNQIIELYKTVEDNANKIIEKEDEVQYLQELLESKKDEIQMLY----EKL 1251 Query: 719 DLTDKLEKMSAEKISELLAK---INHEEQSKI--QTQFGIDAKIQERDLYIENIESELSK 773 + +K + K+ E LAK + E Q K Q +DAK +E ++ + L K Sbjct: 1252 TVANKTAEDLRAKLEEALAKPVPVVDEAQIKDLEQKNHDLDAKNKELLEKLKKFAANLKK 1311 Query: 774 YKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDH 833 + LE +A ++ L RK+ G + + ++ + + + L N L L+ Sbjct: 1312 KNVQCQELEGKLASLQQELEEL-RKSAAAGMSVDDLKEENEQLSQKMHHLNNELHKLLQL 1370 Query: 834 DRVVEKQLLEIEHENKELQKKNQIL------LEEN-QNLQISLSDMQQHYNALVEKANRT 886 +E + +HE EL+++ Q + LEE Q ++ L++ Q+ +E Sbjct: 1371 KYNLETEKQAAQHETLELKERVQAMEANVKELEEKRQEVESQLAEQQKE----LETVRND 1426 Query: 887 DLAES-ESTKYQTQLRDLESNLKRIT-HEHQTLIVQKKKEIEDLEIE-FNTQIESAIR-- 941 D +++ + K + +++ ++R+ HE +T +Q + ++ ++E F+ Q R Sbjct: 1427 DASKNVKIEKCKAIIKEKNKEIQRLQEHERKTSYLQDEIKMAQSKLEDFHNQTMLLGRLK 1486 Query: 942 -DKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQS 1000 DK+ LN + + +E LE ++ + + L +++E + N +L K V+ +Q S Sbjct: 1487 ADKEELNAEMKIQVERCQALEEEVCQGAEKMRKLEVDLEISEEENKKLKSKIVKLEQGIS 1546 Query: 1001 PDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENM 1060 E+ N + + LL K +E Q+ + M +++ KL+ Sbjct: 1547 --LVEERRNSLERQKKLLGDKLDE---KQQEFIQHEDELMQRLANLSQHDEAVEGKLKEK 1601 Query: 1061 EEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKET-KLTFEMNIPKTEGMIISSTIE 1119 EEE+ + +L D + ++LQ + + + QI +E+ K E+ + E ++ + Sbjct: 1602 EEELLELGSKLRDVEYQRDQLQSKLNQLEAQIGAFEESSKRASEL---ENENYNLTQEVA 1658 Query: 1120 PMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLE 1179 + + V ++++ E Q L Q +K+ E ++ + + Sbjct: 1659 ALQAEVKRV-------LAESEAKVLEKDSEIDQLEYELTNQLSKIEDERKQLQENLERTR 1711 Query: 1180 TLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELW 1239 N++L V QE +N L+ + L E L L + + R + + Sbjct: 1712 DSNSDLQDEVVRLQENVNSLEQQRTDLEKETTWLKMQNESLNHDSNELQELRMQIVQDQT 1771 Query: 1240 KQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTME-QVTSLQNK 1298 + + + D H+ +++A + + + +Q +T+ V+++ +VT L+ + Sbjct: 1772 ELENLRAQCDTLAQNHQY--EINALKQQIADMEAIRTQLSQNQTDDQVSVQNEVTKLKER 1829 Query: 1299 LQDKEEHLRNLQEKYADVINQIEILRSEIED 1329 L KE + LQ+K + Q+ ++ED Sbjct: 1830 LDKKEAEVAQLQQKNLQM--QMTASGGQVED 1858 Score = 128 bits (308), Expect = 2e-27 Identities = 274/1421 (19%), Positives = 570/1421 (40%), Gaps = 102/1421 (7%) Query: 212 EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANK-------LLEAAR 264 E T Q + E + +AE ++ Q ++ + S L+E K ++A Sbjct: 454 EATIQAQKEEIETYNQQQAELQENLQEKTVELNVLNANFSVLQEKLKNAGPKPLFPKSAE 513 Query: 265 FEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSL--EIANMT 322 E +E+SKL Q+L++ L KQ ++ + EE L E+ +T Sbjct: 514 EEAEVENSKLKQQLDEANKSMIKSKLKIKQLQKQ-VDSFKKTSAVHEEVVRLTDEVQTLT 572 Query: 323 ELTKKIELLEHLNCQIRQTN-------KELENKLATMGT--ESKAVSSPSKKGSPLISRK 373 + ++E E N Q+ N ELE ++ + T +++ + + + + Sbjct: 573 QRLAEVEE-EKGNLQLHLVNYDGSLPDSELEKRIKILETTCQNQTTAIQLLEEQKIDMTE 631 Query: 374 SGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDT 433 +T ++++ Q+ D + + ++ +E Q L K + D++ ++ + Sbjct: 632 DLNSTKTQLERMRDQVKEHQDQADQSGTVISDHMSSIETEEQ-LEKCVADRDRLVEQVHQ 690 Query: 434 XXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEI 493 D + + +E +E SL V ++ E + + + + KQE+ Sbjct: 691 LEEERSELQQKLDRYVVE-NMELLDKIEKLSLEKV-SSAESIEIVEGLTAKEKQEIESFE 748 Query: 494 KDVNVKDLIEKLKSAEE--QITQLNDEIDAANKNMIKVKSNHKLK--LKQMQKTIDNFSK 549 K + L E +E + NDE D + ++V S + + + N + Sbjct: 749 KACRKQQLAEPPGGVDEVDRDRPSNDE-DDDDDGPLQVHSERRDEPTTGDSEGEDPNSCQ 807 Query: 550 VSDSNKEIVRLTEELHHLSQKVAELEEEKGNL----QLHLVDYDSGRMIESDVYKKMIEM 605 ++ L ++ + + E+ E+ L Q H+ + D R ++ +K + + Sbjct: 808 AKQREEQHSELMHKIELFTNERREVLEKLEALTVENQTHIDELDQLREEHQELVQKHVAL 867 Query: 606 ENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADI-SQLQSDQVCSEIKSVHL 664 E + + +++ E +K LV+EL + ++E + + S QS + + Sbjct: 868 EKVEQELKASLTKTEQEKASLVEELEAAKTLKAKLESEASSTPSSSQSTPSKAAASVIDK 927 Query: 665 EEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKL 724 + AL + E+ +N DK + K L +D +++ + ++E + Sbjct: 928 DSFEQALRSVDNEVTNYNKNK--DKTKKLQISKKLSSDAKNLQKMANSLLEEYYRNLAEC 985 Query: 725 EKMSAEKISELLAKINH-EEQSKIQTQFGIDAKIQERD-LYIENIESELSKYKSRICRLE 782 E M E I +L K+ E + + G+ A+I E I+ ++ ++ + + + R Sbjct: 986 EAMKME-IEQLKDKVQRLPEVDRTEEINGLKAQIMEMTHAQIDKVD-QIDQLREDLERKN 1043 Query: 783 ESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQE-DELVNRLAVL-MDHDRVVEKQ 840 E I ++ R R+A++ E K E EL L +L + +E+ Sbjct: 1044 EEIGELK-REMEAAREAEKSSDEEPELLKVELNSRNDEIRELKKELELLGVKKAGEIEEA 1102 Query: 841 LLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQL 900 ++ KE++ +++ E+ Q L + Q+H N + K E+++ K Q+ Sbjct: 1103 QAKLVAATKEIEILKELVAEQKQQL---IETYQEHENEIAGKLKEIQDYENQAQKMADQV 1159 Query: 901 RDLE-----------SNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEK 949 DL +++KR E ++L ++ EIE + +T I K + + Sbjct: 1160 EDLNRQLVEVGEKYSNDMKRQVEELKSLTQKQSDEIEHKQETIDTLNNQIIELYKTVEDN 1219 Query: 950 YEKNIEY---VTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQ 1006 K IE V L+ L+ K+ I+ L + NK +L K + P E Sbjct: 1220 ANKIIEKEDEVQYLQELLESKKDEIQMLYEKLTVANKTAEDLRAKLEEALAKPVPVVDEA 1279 Query: 1007 YINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQR 1066 I ++ + N L K++E++ +K + E KLA +LE + + Sbjct: 1280 QIKDLEQKNHDLDAKNKELLEKLKKFAANLKKKNVQCQELEGKLASLQQELEELRKSAA- 1338 Query: 1067 VSKQLLDSKQHNEELQILVREQDDQIKELKETK--LTFEMNIPKTEGMIISSTIEPMSDD 1124 + D K+ NE+L + ++++ +L + K L E + E + + ++ M + Sbjct: 1339 AGMSVDDLKEENEQLSQKMHHLNNELHKLLQLKYNLETEKQAAQHETLELKERVQAMEAN 1398 Query: 1125 ANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTE 1184 ++ ++ E+++ E ++ A N ++++C I + Sbjct: 1399 VKELEEKRQEVES-----QLAEQQK---ELETVRNDDASKNVKIEKCKAIIKEKNKEIQR 1450 Query: 1185 LTGHDVVN---QEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQ 1241 L H+ Q++I +SKLE + + LL + + +++ + + E + ++ Sbjct: 1451 LQEHERKTSYLQDEIKMAQSKLEDFHNQT-MLLGRLKADKEELNAEMKIQ-VERCQALEE 1508 Query: 1242 HLAQREADFQKTEHELRV---QLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTS--LQ 1296 + Q +K E +L + + +SK +L + S +E N + +++ L Sbjct: 1509 EVCQGAEKMRKLEVDLEISEEENKKLKSKIVKLEQGI-SLVEERRNSLERQKKLLGDKLD 1567 Query: 1297 NKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTEN 1356 K Q+ +H L ++ A++ E + ++++++ N Sbjct: 1568 EKQQEFIQHEDELMQRLANLSQHDEAVEGKLKEKEEELLELGSKLRDVEYQRDQLQSKLN 1627 Query: 1357 QSYKQMQ--EQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDS 1414 Q Q+ E+S +E + + + ++EAKVLE KDS Sbjct: 1628 QLEAQIGAFEESSKRASELENENYNLTQEVAALQAEVKRVLAESEAKVLE-------KDS 1680 Query: 1415 EIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYE 1474 EI Q +E T L++ DE R+QL E +R D + + E ++RL+ + N+ + Sbjct: 1681 EIDQLEYELTNQLSKIEDE----RKQLQENLERTRDSNSDLQDE--VVRLQENVNSLEQQ 1734 Query: 1475 TMQKESEIERVKL-IEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEI 1533 E E +K+ E LN E L Q+ + LE A + T +N + EI Sbjct: 1735 RTDLEKETTWLKMQNESLNHDSNELQELRMQIVQDQTELENLRA---QCDTLAQNHQYEI 1791 Query: 1534 VTLNDEITNLQNM-VRASSSKIQKHVSFASDTKQGRDEQLD 1573 L +I +++ + + S ++ VS ++ + + E+LD Sbjct: 1792 NALKQQIADMEAIRTQLSQNQTDDQVSVQNEVTKLK-ERLD 1831 Score = 112 bits (269), Expect = 9e-23 Identities = 234/1151 (20%), Positives = 479/1151 (41%), Gaps = 120/1151 (10%) Query: 523 NKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQ 582 ++ + ++ +L+LKQ+++ + K+ +S ++ + + L Q +++L++ L+ Sbjct: 2173 DRELENLREQSELQLKQIREQDE---KLRESGQQYTTVQSTVERLQQDLSQLQQRYAELE 2229 Query: 583 LHLVDYDSGRMIESDVYKKMIEMENLAETRLK-AISLLESQKFDLVQELHILQQKYDEVE 641 HL + E + + +N +LK I +L +Q L EL DE Sbjct: 2230 AHLQSTIASHQTEVEGKMAALAEQNDEFLQLKDEIDILRAQNASLSYEL-------DEAT 2282 Query: 642 DKLADISQ-LQSDQ--VCSEIKSVHLEEQ------IDALSASKKELALVIENLKLDKEQL 692 KL +++Q LQ +Q VC + +H +E + + A+ V E+L + K+ Sbjct: 2283 AKLKNLAQSLQEEQLKVCQLEEQLHSKESAVAAPSVSSFFANSGAQEPVFEDLVVPKKAY 2342 Query: 693 YGTIKDLENDKEDIMNK--LQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQ 750 T E + + K + + + + +E + ++++ L ++N ++ +++ Q Sbjct: 2343 LCTPSASEEQDDWSVEKPMVMSTMAPSQRSAGLVESVDLQELANL-RELNEQQMKQLREQ 2401 Query: 751 FGIDAKIQERDLYIENIESELSKYKSRICRLE----ESIAVMEDRRYSLERKADQLGSYL 806 ++ Q +E ++ ELS+ + R +LE ++A + +L Q S Sbjct: 2402 ADQHSQTQAN---VEQLQQELSQLQQRYAQLEGHLNTTLASHQIELEALRNHQTQQNSQS 2458 Query: 807 QEKQKAYSEYTIQEDELVNRLAVL-MDHDRVVEKQ--LLEIEHENKELQKKNQILLEENQ 863 QE+QK + + + L+ R L D D ++ Q L ++ +N L+++ + + Sbjct: 2459 QEEQKKLKD---ELNHLMQRNQALEQDRDAYLQLQDELDILKAQNASLRQEVDEKSDRIK 2515 Query: 864 NLQISLSDMQQHYNALVEK-ANRTDLAESESTKYQTQLRDLESNL--KRITHEHQTLIVQ 920 + +L++ + + L E+ A R S + + Q + + + + IT + + Sbjct: 2516 RVCHTLTEQETRVSDLEEQLATREQHPPSTAAFFGGQQQPPAAAVFEEIITPKKAYEVEP 2575 Query: 921 KKKEIEDLEIEFNTQIESAIRDKK------VLNEKYEKNIEYVTQLEAQLQEYKNNIENL 974 +E + E+A+ +K L + + +Y+ QLE + + I L Sbjct: 2576 TPSSAIQVEDDCWGAEEAALEEKHQQTSSVALERRISEKDDYIRQLEMEKERLLQEIVEL 2635 Query: 975 NMNVEELNKMNLELIDK-HVQKQQTQSPDYTEQYINEINKLNALLKQKD---EEIIALNQ 1030 + +L K E K ++++ S + +E + +LN +K + E+ A + Sbjct: 2636 KVKSGKLLKKLKEYKTKSETLQRRSASMETSELDLAIQEELNTQIKTLEGRLSELQAERE 2695 Query: 1031 KINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDD 1090 K + + S + + + +FT E + +M+ Q+ K+ N +LQ L D+ Sbjct: 2696 KESTEKDSLLKRIDVLVAANERFTEMKERQDVQMEI---QVAKIKELNLKLQQLEDWGDE 2752 Query: 1091 QIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANN--VDXXXXXXXXXXXXLKVQEEE 1148 E KE+K ++ + +++ ++ + + + VD V+ E Sbjct: 2753 S--EQKESKPVEQVQPEAVDVAPLNARVQELEREVQDLKVDNEELQALLDEEKANVEILE 2810 Query: 1149 EFIQERS-VLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLN 1207 + +Q++ +Q+ K++ Q+ T LE+LN + ++ L ++L+QL Sbjct: 2811 KRVQQKDREIQDLIEKIDLLSQDSQTIKTNLESLNQQ-------KSQETEDLSTRLKQLM 2863 Query: 1208 TENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHEL-----RVQLS 1262 ++N L + ++R+ ++ Q + A+L +Q + Q A Q E E+ R++ Sbjct: 2864 SKNTELTQQIEKMRTE---SLFQSSEQEAKLQEQ-VQQLSAQLQYKEAEIVHLGERIEQQ 2919 Query: 1263 AFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQD-------KEEHLRNLQEKYAD 1315 A E + + L+ + + QE N ++Q+ + + +LQ KE EK + Sbjct: 2920 AREDQTQSLVQEILAKNQEINNLKSRVQQLEAERQELQHNLTLQITKELASSRPDEKQSP 2979 Query: 1316 VINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENA 1375 ++++E L E++ EK L E++ + E NI E Sbjct: 2980 RVSELERLNRELQAEK---HQMEQELQVLNDQVLRSLELEDRMKGTVLELDAKNIEIEAL 3036 Query: 1376 Q-----LKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQR 1430 + LK++S A +L Q++ E + Y ITL QR Sbjct: 3037 KTSLELLKQASEASGESASSSEQSTPTAGKSEEDLRKQIKKLSRERSELEANYRITLEQR 3096 Query: 1431 NDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEE 1490 + + Q+VE E+ +++A H + + E + L EE Sbjct: 3097 DAHWS----QVVE----------ERGAQVA------ESWKQHVDMREAEFSVIEKSLREE 3136 Query: 1491 LNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEIT-NLQNMVRA 1549 ++ L +E + E+ A N M+ ALE QE+EIVTL +++ R Sbjct: 3137 ID-------RLQGDGSETPSSSEQSEAVQN-MKAALEAQELEIVTLKEQLAIRSAEYARL 3188 Query: 1550 SSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDLAMYMLHQRDVRCXXXXXX 1609 ++ V AS+ + D VPR+EL+LA+YM++QRD+RC Sbjct: 3189 AAQVDPFAVKHASNMVTSEPRPQPAAQDG---DKVPRSELELALYMIYQRDMRCEELELE 3245 Query: 1610 XXXXXXXRDTL 1620 RD+L Sbjct: 3246 LRNLLTERDSL 3256 Score = 111 bits (268), Expect = 1e-22 Identities = 262/1299 (20%), Positives = 539/1299 (41%), Gaps = 109/1299 (8%) Query: 299 SIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKL-ATMGTESK 357 S+ +T EK +L M + K+ E ++ + EL++KL +T T + Sbjct: 121 SVPIRARSETPGSEKINLLRQQMEQNRLKMAARESHKREMEERVIELKHKLESTQQTLER 180 Query: 358 AVSSPSKKG--SPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQ 415 +V G + L K GR ++ S +QL ++ + D + + LE ++ Sbjct: 181 SVEFGRSTGDLTLLTPLKMGRFEFNRSTSDLTQLVGSGVSSNFDVE----RLNYLEGRVK 236 Query: 416 SLNKDLVDKEYV-ISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHV-----G 469 L ++L KE + EKD + + + + + + SL+ G Sbjct: 237 VLEQELAAKESQRVPEKDEVVQGLERKILDLEEALKEKECVIEARTQAVSLMSENLSLKG 296 Query: 470 TNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKL-------KSAEEQITQLNDEIDAA 522 NT D+ E K QE + + N + N+K +++L KS + ++N+ ++ A Sbjct: 297 KNTVDLLEDTK-QEMYRMQSNFVQAESNMKAELDRLQVELDERKSKISNLEEMNNILETA 355 Query: 523 NKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIV-RLTEELHHLSQKVAELEEEKGNL 581 ++ ++ K KL+ +Q S+++ N+ + R+TE + + + E E+ Sbjct: 356 RYDLTVENASLKQKLEDVQDFSTKISELNKLNQSLQHRITELESQKYEFITDAEAEQAKF 415 Query: 582 QLHLVDY----DSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKY 637 Y D +E ++ +K E+L E + +++QK ++ + Sbjct: 416 GASDEKYQELLDRIHELEEELSRKAAPQEDLLEKIRSLEATIQAQKEEIETYNQQQAELQ 475 Query: 638 DEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIK 697 + +++K +++ L ++ + K + + L E +EN KL K+QL K Sbjct: 476 ENLQEKTVELNVLNANFSVLQEKLKNAGPK--PLFPKSAEEEAEVENSKL-KQQLDEANK 532 Query: 698 DLENDKEDI--MNKLQNYIQENMDLTDKLEKMSAE--KISELLAKINHEEQSKIQTQF-G 752 + K I + K + ++ + +++ +++ E +++ LA++ EE+ +Q Sbjct: 533 SMIKSKLKIKQLQKQVDSFKKTSAVHEEVVRLTDEVQTLTQRLAEVE-EEKGNLQLHLVN 591 Query: 753 IDAKIQERDLY--IENIESELSKYKSRICRLEES-IAVMED---RRYSLERKADQLGSYL 806 D + + +L I+ +E+ + I LEE I + ED + LER DQ+ + Sbjct: 592 YDGSLPDSELEKRIKILETTCQNQTTAIQLLEEQKIDMTEDLNSTKTQLERMRDQVKEHQ 651 Query: 807 QEKQKA---YSEY--TIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEE 861 + ++ S++ +I+ +E + + D DR+VE Q+ ++E E ELQ+K + E Sbjct: 652 DQADQSGTVISDHMSSIETEEQLEKCVA--DRDRLVE-QVHQLEEERSELQQKLDRYVVE 708 Query: 862 NQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEH-----QT 916 N L L +++ V A ++ E + K + ++ E ++ Sbjct: 709 NMEL---LDKIEKLSLEKVSSAESIEIVEGLTAKEKQEIESFEKACRKQQLAEPPGGVDE 765 Query: 917 LIVQKKKEIEDLEIEFNTQIESAIRDKKVL--NEKYEKNIEYVTQLEAQLQEYKNNIENL 974 + + ED + + Q+ S RD+ +E + N Q E Q E + IE Sbjct: 766 VDRDRPSNDEDDDDDGPLQVHSERRDEPTTGDSEGEDPNSCQAKQREEQHSELMHKIELF 825 Query: 975 -NMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKIN 1033 N E L K+ ++ + D + E+ + + L++ ++E+ A K Sbjct: 826 TNERREVLEKLEALTVENQTHIDEL---DQLREEHQELVQKHVALEKVEQELKASLTKTE 882 Query: 1034 NAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIK 1093 + S + + ++ A+ ++ + Q + S + + +R D+++ Sbjct: 883 QEKASLVEELEAAKTLKAKLESEASSTPSSSQSTPSKAAASVIDKDSFEQALRSVDNEV- 941 Query: 1094 ELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQE 1153 + N KT+ + IS + +S DA N+ + E E E Sbjct: 942 ------TNYNKNKDKTKKLQIS---KKLSSDAKNLQKMANSLLEEYYR-NLAECEAMKME 991 Query: 1154 RSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNL 1213 L+++ +L E+ +I L+ E+T + +QI+QL+ LE+ N E Sbjct: 992 IEQLKDKVQRL-PEVDRT-EEINGLKAQIMEMTHAQIDKVDQIDQLREDLERKNEE---- 1045 Query: 1214 LSTVAELRSSISSA--VDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQL 1271 + EL+ + +A ++ E EL K L R + ++ + EL + + E+ Sbjct: 1046 ---IGELKREMEAAREAEKSSDEEPELLKVELNSRNDEIRELKKELELLGVKKAGEIEEA 1102 Query: 1272 LDSVQSSTQE-ETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDE 1330 + ++T+E E K + EQ L Q+ E + ++ D NQ + + ++ED Sbjct: 1103 QAKLVAATKEIEILKELVAEQKQQLIETYQEHENEIAGKLKEIQDYENQAQKMADQVEDL 1162 Query: 1331 KVAFXXXXXXXXXXXXXXXXDLR--TENQSYK-QMQEQSILNINEENAQLKKSSXXXXXX 1387 +L+ T+ QS + + ++++I +N + +L K+ Sbjct: 1163 NRQLVEVGEKYSNDMKRQVEELKSLTQKQSDEIEHKQETIDTLNNQIIELYKT------- 1215 Query: 1388 XXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKR 1447 ++ + E +V L LE K EI Q +E LT N E++R +L E Sbjct: 1216 VEDNANKIIEKEDEVQYLQELLESKKDEI-QMLYE---KLTVANKTAEDLRAKL--EEAL 1269 Query: 1448 IEDLTYEKESELAILRLKMHE-NANHYETMQKESEIERVKLIEELNVKITESVSLNKQVA 1506 + + E+++ L K H+ +A + E ++K K L K + L ++A Sbjct: 1270 AKPVPVVDEAQIKDLEQKNHDLDAKNKELLEKLK-----KFAANLKKKNVQCQELEGKLA 1324 Query: 1507 ELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQN 1545 L + L EE+ K+ ++++ + E L+ ++ +L N Sbjct: 1325 SLQQEL-EELRKSAAAGMSVDDLKEENEQLSQKMHHLNN 1362 Score = 99.5 bits (237), Expect = 7e-19 Identities = 167/864 (19%), Positives = 381/864 (44%), Gaps = 66/864 (7%) Query: 474 DVNEIAKVQEQLKQELNDEIKDVNVKDLIE-KLKSAEEQITQLNDEIDAANKNMIKVKSN 532 D+ E+A ++E +Q++ + + + ++ +++++QL ++ ++ Sbjct: 2380 DLQELANLRELNEQQMKQLREQADQHSQTQANVEQLQQELSQLQQRYAQLEGHLNTTLAS 2439 Query: 533 HKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVD-YDSG 591 H+++L+ ++ + S S +E +L +EL+HL Q+ LE+++ + L L D D Sbjct: 2440 HQIELEALRN--HQTQQNSQSQEEQKKLKDELNHLMQRNQALEQDR-DAYLQLQDELDIL 2496 Query: 592 RMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQ 651 + + + +++ E + + ++ E++ DL ++L +Q Q Sbjct: 2497 KAQNASLRQEVDEKSDRIKRVCHTLTEQETRVSDLEEQLATREQHPPSTAAFFGGQQQPP 2556 Query: 652 SDQVCSEI---KSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLE---NDKED 705 + V EI K + E + + ++ E L+++ + LE ++K+D Sbjct: 2557 AAAVFEEIITPKKAYEVEPTPSSAIQVEDDCWGAEEAALEEKHQQTSSVALERRISEKDD 2616 Query: 706 IMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIE 765 + +L+ E L ++ ++ K +LL K+ E ++K +T A ++ +L + Sbjct: 2617 YIRQLE---MEKERLLQEIVELKV-KSGKLLKKLK-EYKTKSETLQRRSASMETSELDLA 2671 Query: 766 NIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVN 825 I+ EL+ ++I LE ++ ++ R + D L + A +T ++ Sbjct: 2672 -IQEELN---TQIKTLEGRLSELQAEREKESTEKDSLLKRIDVLVAANERFTEMKERQDV 2727 Query: 826 RLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANR 885 ++ + + + + +L ++E E ++K +E+ Q + ++ + NA V++ R Sbjct: 2728 QMEIQVAKIKELNLKLQQLEDWGDESEQKESKPVEQVQPEAVDVAPL----NARVQELER 2783 Query: 886 T--DLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDK 943 DL + ++ + Q L + ++N++ + Q QK +EI+DL IE +I+ +D Sbjct: 2784 EVQDL-KVDNEELQALLDEEKANVEILEKRVQ----QKDREIQDL-IE---KIDLLSQDS 2834 Query: 944 KVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQT----Q 999 + + T LE+ Q+ E+L+ +++L N EL + ++K +T Q Sbjct: 2835 QTIK----------TNLESLNQQKSQETEDLSTRLKQLMSKNTELTQQ-IEKMRTESLFQ 2883 Query: 1000 SPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLEN 1059 S + + ++ +L+A L+ K+ EI+ L ++I Q + ++ ++ N Sbjct: 2884 SSEQEAKLQEQVQQLSAQLQYKEAEIVHLGERIE--QQAREDQTQSLVQEILAKNQEINN 2941 Query: 1060 MEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIE 1119 ++ +Q++ + + QHN LQI +E + K++ E+ E +E Sbjct: 2942 LKSRVQQLEAERQEL-QHNLTLQI-TKELASSRPDEKQSPRVSELERLNRELQAEKHQME 2999 Query: 1120 PMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLE 1179 N+ ++ + + I+ ++ + S +L + E + Sbjct: 3000 QELQVLNDQVLRSLELEDRMKGTVLELDAKNIEIEAL--KTSLELLKQASEASGESASSS 3057 Query: 1180 TLNTELTGHDVVNQEQINQLKSKLEQLNTEND-NLLSTVAELRSSISSAVDQRGFEIAEL 1238 +T G ++E + + KL + +E + N T+ + + S V++RG ++AE Sbjct: 3058 EQSTPTAGK---SEEDLRKQIKKLSRERSELEANYRITLEQRDAHWSQVVEERGAQVAES 3114 Query: 1239 WKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQN- 1297 WKQH+ REA+F E LR ++ + S S+ E++ + M+ Q Sbjct: 3115 WKQHVDMREAEFSVIEKSLREEIDRLQGD-----GSETPSSSEQSEAVQNMKAALEAQEL 3169 Query: 1298 KLQDKEEHLRNLQEKYADVINQIE 1321 ++ +E L +YA + Q++ Sbjct: 3170 EIVTLKEQLAIRSAEYARLAAQVD 3193 Score = 78.6 bits (185), Expect = 1e-12 Identities = 249/1393 (17%), Positives = 562/1393 (40%), Gaps = 116/1393 (8%) Query: 212 EDTKQQMTKMQENFIAMEAEWKDEKQRLLK-DIESKDVRISSLEEANKLLEA-ARFEISL 269 ++ Q++ + ++ A+E + K++++ LL+ + +DV + +KL + A+ Sbjct: 1578 DELMQRLANLSQHDEAVEGKLKEKEEELLELGSKLRDVEYQRDQLQSKLNQLEAQIGAFE 1637 Query: 270 EHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIE 329 E SK A ELE K+ + E + ++ EK S EI + + E Sbjct: 1638 ESSKRASELENENYNLTQEVAALQAEVKRVL---AESEAKVLEKDS-EIDQL-----EYE 1688 Query: 330 LLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQL 389 L L+ +I K+L+ L + + + ++ + T + ++ W ++ Sbjct: 1689 LTNQLS-KIEDERKQLQENLERTRDSNSDLQDEVVRLQENVNSLEQQRTDLEKETTWLKM 1747 Query: 390 SSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLI 449 +E+LN D+ NE+ +L M I +D + E + ++ DT I Sbjct: 1748 QNESLNHDS------NELQELRMQIV---QDQTELENLRAQCDTLAQNHQYEINALKQQI 1798 Query: 450 AQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAE 509 A ++ Q + + V NE+ K++E+L + K+ V L +K + + Sbjct: 1799 ADMEAIRTQLSQNQTDDQVSVQ----NEVTKLKERLDK------KEAEVAQLQQK--NLQ 1846 Query: 510 EQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQ 569 Q+T +++ ++ L++ + ++N + DS + +++ ++L S Sbjct: 1847 MQMTASGGQVEDPFSSLQATPERSTAALEEKIRELENDATWKDSRIQELQIEKDLADGS- 1905 Query: 570 KVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLES-QKFDLVQ 628 LEE + LQ+ + + +E+ + +K E+E L++ + + + Q+ + + Sbjct: 1906 ----LEELRKQLQMLQQNVQNSEALEAQLAQKSSELEQLSKQLFQTVPAKKPVQEVEAIP 1961 Query: 629 ELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKK--ELALV---IE 683 Q E + + + + V +++Q+ A SAS++ EL ++ IE Sbjct: 1962 TFSTSQFFAAPSESSAVTLFDTAGEGWGWD-EPVAVQQQV-ATSASEQSNELQMLRDEIE 2019 Query: 684 NLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSA---EKISELLAKIN 740 LK E +++L+ ++++ Y Q+ D D L +A +++ E AK+ Sbjct: 2020 QLKARNEAAAKEVQELQGRLGTVVDRDSEY-QQLKDEVDILRSQNASLNQEVDEKAAKLR 2078 Query: 741 HEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKAD 800 QS ++ Q + ++++E+ L+ S V ED + +KA Sbjct: 2079 SVAQSLLEEQVKV-SQLEEQ-LHSNESAVVAPSVSSFFADSASQGPVFED--LIVPKKAY 2134 Query: 801 QLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLE 860 E+++ E++++E +V+ A H ++ + E EN L++++++ L+ Sbjct: 2135 MCTPSASEERE---EWSVEEPAVVS-TAATSQHAVGFMSKVDDRELEN--LREQSELQLK 2188 Query: 861 ENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQ 920 + + L + Q Y + R + + ++ Q + +LE++L+ HQT + Sbjct: 2189 QIREQDEKLRESGQQYTTVQSTVER---LQQDLSQLQQRYAELEAHLQSTIASHQTEVEG 2245 Query: 921 KKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVT----QLEAQLQEYKNNIENLNM 976 K + + EF Q++ I + N ++ T L LQE + + L Sbjct: 2246 KMAALAEQNDEF-LQLKDEIDILRAQNASLSYELDEATAKLKNLAQSLQEEQLKVCQLEE 2304 Query: 977 NV-EELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNA 1035 + + + + + Q P + + + + L ++++ + + Sbjct: 2305 QLHSKESAVAAPSVSSFFANSGAQEPVFEDLVVPKKAYLCTPSASEEQD----DWSVEKP 2360 Query: 1036 QVSYMSMVSDYESKLAQFT--TKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIK 1093 V S + L + +L N+ E ++ KQL + + + Q V + ++ Sbjct: 2361 MVMSTMAPSQRSAGLVESVDLQELANLRELNEQQMKQLREQADQHSQTQANVEQLQQELS 2420 Query: 1094 ELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQE 1153 +L++ E ++ T + S IE +A K+++E + + Sbjct: 2421 QLQQRYAQLEGHLNTT---LASHQIEL---EALRNHQTQQNSQSQEEQKKLKDELNHLMQ 2474 Query: 1154 RSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNL 1213 R+ EQ +LQ+ ++ L+ N L ++I ++ L + T +L Sbjct: 2475 RNQALEQDRDAYLQLQD---ELDILKAQNASLRQEVDEKSDRIKRVCHTLTEQETRVSDL 2531 Query: 1214 LSTVAELRSSISSAV----DQRGFEIAELWKQHLAQREA-DFQKT-EHELRVQLSAFESK 1267 +A S Q+ A ++++ + ++A + + T ++V+ + ++ Sbjct: 2532 EEQLATREQHPPSTAAFFGGQQQPPAAAVFEEIITPKKAYEVEPTPSSAIQVEDDCWGAE 2591 Query: 1268 YEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQE---KYADVINQIE--I 1322 L + Q ++ + ++ E+ ++ +KE L+ + E K ++ +++ Sbjct: 2592 EAALEEKHQQTSSVALERRIS-EKDDYIRQLEMEKERLLQEIVELKVKSGKLLKKLKEYK 2650 Query: 1323 LRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSX 1382 +SE + A ++T ++Q + E+++ LK+ Sbjct: 2651 TKSETLQRRSASMETSELDLAIQEELNTQIKTLEGRLSELQAEREKESTEKDSLLKRIDV 2710 Query: 1383 XXXXXXXXXXXRV-NDAE-----AKVLELT---HQLELKDSEIYQKTHEYTITLTQRNDE 1433 + D + AK+ EL QLE E QK + + + Sbjct: 2711 LVAANERFTEMKERQDVQMEIQVAKIKELNLKLQQLEDWGDESEQKESKPVEQVQPEAVD 2770 Query: 1434 FENVRQQLVEYEKRIEDLTYEKESELAIL-RLKMHENANHYETMQKESE----IERVKLI 1488 + ++ E E+ ++DL + E A+L K + QK+ E IE++ L+ Sbjct: 2771 VAPLNARVQELEREVQDLKVDNEELQALLDEEKANVEILEKRVQQKDREIQDLIEKIDLL 2830 Query: 1489 EELNVKI-TESVSLNKQ----VAELNKALEEEVAKTNEMQTALENQEIE-IVTLNDEITN 1542 + + I T SLN+Q +L+ L++ ++K E+ +E E + +++ Sbjct: 2831 SQDSQTIKTNLESLNQQKSQETEDLSTRLKQLMSKNTELTQQIEKMRTESLFQSSEQEAK 2890 Query: 1543 LQNMVRASSSKIQ 1555 LQ V+ S+++Q Sbjct: 2891 LQEQVQQLSAQLQ 2903 Score = 40.7 bits (91), Expect = 0.32 Identities = 146/741 (19%), Positives = 295/741 (39%), Gaps = 92/741 (12%) Query: 147 LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEK-DQIIEAKNKATTXXXXXXXXXXX 205 L I EKD+ + L+++ + + I++L+ K + ++ E K K+ T Sbjct: 2607 LERRISEKDDYIRQLEMEKERLLQEIVELKVKSGKLLKKLKEYKTKSETLQRRSASMETS 2666 Query: 206 XXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKD--IESKDVRISSLEEANKLLEAA 263 ++ K E ++ E + + EK+ KD ++ DV +++ E ++ E Sbjct: 2667 ELDLAIQEELNTQIKTLEGRLS-ELQAEREKESTEKDSLLKRIDVLVAANERFTEMKERQ 2725 Query: 264 RFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTE 323 ++ ++ +K+ +EL + +E E ++ A + E Sbjct: 2726 DVQMEIQVAKI-KELNLKLQQLEDWGDESEQKESKPVEQVQPEAVDVAPLN----ARVQE 2780 Query: 324 LTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISR-----KSGRNT 378 L ++++ L+ N +++ L+ + A + K V ++ LI + + + Sbjct: 2781 LEREVQDLKVDNEELQAL---LDEEKANVEILEKRVQQKDREIQDLIEKIDLLSQDSQTI 2837 Query: 379 ASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXX 438 + ++S Q S ET +D ++ K ++K + Q + K + + SE++ Sbjct: 2838 KTNLESLNQQKSQET--EDLSTRL-KQLMSKNTELTQQIEKMRTESLFQSSEQEAKLQEQ 2894 Query: 439 XXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNV 498 L AQLQ + + ++H+G E + +E Q L EI N Sbjct: 2895 V------QQLSAQLQYKEAE------IVHLGERIEQ-----QAREDQTQSLVQEILAKNQ 2937 Query: 499 KDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIV 558 + I LKS ++ QL E N+ + + +K S++ N+E Sbjct: 2938 E--INNLKS---RVQQLEAERQELQHNLTLQITKELASSRPDEKQSPRVSELERLNRE-- 2990 Query: 559 RLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISL 618 L E H + Q++ L ++ L L D G ++E D K IE+E L + Sbjct: 2991 -LQAEKHQMEQELQVLNDQVLR-SLELEDRMKGTVLELDA--KNIEIEALKTS------- 3039 Query: 619 LESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKEL 678 L +L+Q E + A S+ QS + + L +QI LS + EL Sbjct: 3040 -----------LELLKQA-SEASGESASSSE-QSTPTAGKSEE-DLRKQIKKLSRERSEL 3085 Query: 679 ALVIENLKLDKEQLYGTIKDLENDK-EDIMNKLQNYIQENMDLTDKLEKMSAEKISELLA 737 N ++ EQ + ++ + + ++ +EK E+I L Sbjct: 3086 E---ANYRITLEQRDAHWSQVVEERGAQVAESWKQHVDMREAEFSVIEKSLREEIDRLQG 3142 Query: 738 KINHEEQSKIQTQF--GIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSL 795 + S Q++ + A ++ ++L I ++ +L+ + RL + +++ Sbjct: 3143 DGSETPSSSEQSEAVQNMKAALEAQELEIVTLKEQLAIRSAEYARLAAQV-----DPFAV 3197 Query: 796 ERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKN 855 + ++ + S + + A + EL LA+ M + R + + LE+E N Sbjct: 3198 KHASNMVTSEPRPQPAAQDGDKVPRSEL--ELALYMIYQRDMRCEELELELRN------- 3248 Query: 856 QILLEENQNLQISLSD-MQQH 875 LL E +LQ+ LS+ ++QH Sbjct: 3249 --LLTERDSLQLRLSNALRQH 3267 >UniRef50_A2DLG0 Cluster: Viral A-type inclusion protein, putative; n=1; Trichomonas vaginalis G3|Rep: Viral A-type inclusion protein, putative - Trichomonas vaginalis G3 Length = 3369 Score = 234 bits (572), Expect = 2e-59 Identities = 296/1498 (19%), Positives = 657/1498 (43%), Gaps = 118/1498 (7%) Query: 143 DVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXX 202 +++ TI EK + + L ++ + ++ ++ EKIN ++ + KN Sbjct: 173 EISEKEKTINEKSSKIEELNQQISEKDNSLKEMTEKINNLEEENKQKN-------SRIEE 225 Query: 203 XXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEA 262 D + ++ + E E++ + + +++ K+ +S L E K ++ Sbjct: 226 LQQQLESLRNDDENRINNLYEELSQKESKINELNELMMQQQTGKETILSQLNEQIKEKDS 285 Query: 263 ARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMT 322 E+ SKL E+ Q K + EEK E++++ S + + + Sbjct: 286 KIGELEENVSKLESEISQKESNINELSSQVSEKDKM-VNDISEEKNELQKQLSDQNSMID 344 Query: 323 ELTKKI-ELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASK 381 EL ++I EL ++L+ ++ E ++K + +E + S K+ ++ + G K Sbjct: 345 ELNEQIKELTDNLSKSTTEST-EKDSKNQELISEKETEISHLKEEISKLTEQHGEK--DK 401 Query: 382 MKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKE-------YVISEKDTX 434 + +L+ + QD + K + I++L++++ +L +K+ + + EKD Sbjct: 402 L---IQELTEQIQTQDINLKQKDSNISELQVLVSQKETELSEKDNSINEFIHKLEEKDLQ 458 Query: 435 XXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEI- 493 K++ I +L + + SL + + E + +E + N+E+ Sbjct: 459 IKELNEQLNNKESQINELNAQISD--KENSLQEITDKVHTLEETVQNKETEINQKNEELS 516 Query: 494 -KDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSD 552 ++ + +L E + + +I Q N+EI + N + ++ K +Q+ D + Sbjct: 517 ERETKINELNEIISQKDSEIQQKNEEISSNNSKIDELNQQISNKENSLQELTDKVHSLET 576 Query: 553 SNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETR 612 N E ++ L++ V+E EEE LQ + ++ D K+ EM + Sbjct: 577 KNSE---QETQIDELTKLVSEKEEENNKLQETIQTKETE---IKDKQSKVDEMNQEISDK 630 Query: 613 LKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCS-EIKSVHLEEQID-- 669 K+I + + L +E + DE++++++ I+ + + + + + +ID Sbjct: 631 DKSIEEITERVNKLEEENKTKNSQIDEMKEQISSITTNEETAISTLNTQLNNKNNEIDLL 690 Query: 670 --ALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKM 727 L + + E I L +LY I + + ++ ++ + QE +D +KL+ + Sbjct: 691 HQQLQSKETENEKAINELNDKLNKLYEEIANKNTNITELNEQISSKNQEIVDRDNKLQSL 750 Query: 728 SA------EKISELLAKIN--HEEQSKIQTQFG-IDAKIQERDLYIENIESELSKYKSRI 778 E+I E +KI ++ SK ++ + +I + IE + +E++ + I Sbjct: 751 GTELNQKNEEIKEKDSKIGEFNDLVSKKDSEINQLQEEIADISSKIEELNNEIATKDASI 810 Query: 779 CRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVE 838 L IA + + SL+ + L S EK+ S+ ++ DE + + V+ Sbjct: 811 LELNNKIAEKDLKIKSLDEEKSSLQSKPAEKENDISDLLVKYDEKCSEI-------EAVQ 863 Query: 839 KQLLEIEHENKELQK-KNQILLEENQNLQISLSDMQQHYNALVEK------ANRTDLAES 891 +L + + ENKE ++ +Q + E+++ + S + + L EK N + AE Sbjct: 864 SELAKKDKENKEFEELMSQAISEKDEEISKSKNGISSLQEKLAEKEKEINSKNEANTAEK 923 Query: 892 ESTKYQTQLRDLE-SNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKY 950 E RD E SNL + E + I K + I E + N IE + + +NEK Sbjct: 924 EENSKLISQRDEEISNLNKSIDELRKEISTKDETISQFESKINELIEEISKKELTINEKE 983 Query: 951 EKNI---EYVTQLEAQLQEYKNNIENLNMNVEEL------NKMNLELIDKHVQKQQTQSP 1001 K E +TQ E ++ K + + + E+ + ++ +++ VQ ++T+ Sbjct: 984 TKIAELNEQITQKENEINGLKEAEKVMETKISEIESQLTEKEKSINELEETVQNKETEIN 1043 Query: 1002 DYTEQYI---NEINKLNALLKQKDEEIIALNQKI--NNAQVSYMS-MVSDYESKLAQFTT 1055 E+ +IN+LN ++ QKD EI N++I NN+++ ++ +S+ E+ L + T Sbjct: 1044 QKNEELSERETKINELNEIISQKDSEIQQKNEEISSNNSKIDELNQQISNKENSLQELTD 1103 Query: 1056 KL-----ENMEEEMQ--RVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPK 1108 K+ +N E+E Q ++K + + ++ N +LQ ++ ++ +IK+ K++K+ EMN Sbjct: 1104 KVHSLETKNSEQETQIEELTKLVSEKEEENNKLQETIQTKETEIKD-KQSKVD-EMNQEI 1161 Query: 1109 TEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTEL 1168 ++ +IE +++ N ++ +K Q E + + + +LN + Sbjct: 1162 SDK---DKSIEEITERVNKLEEENKTKNSQIDEMKEQISSITTNEETAISTLNTQLNNKN 1218 Query: 1169 QECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAV 1228 E QL++ TE+ + E+I++ + L+ TE + EL IS Sbjct: 1219 NEIDLLHQQLQSKETEIKQLN----EEISERNNALQTKETEIKEKELKINELNDIISKKE 1274 Query: 1229 DQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETN---K 1285 +++ E L +++ + + + +EL +L E + +Q S + Q T+ K Sbjct: 1275 EEKA-EKESLLNENINKLNTERESQINELSEKLLKLEEQLKQETLSNEDMKQTNTSLSQK 1333 Query: 1286 IVTME-QVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKV---AFXXXXXXX 1341 I M Q++ ++LQ+ + + L + +D + L+ EI+++ V Sbjct: 1334 IDEMAFQLSDKTSQLQELNQQITVLSSQISDKDKTVNDLQEEIKEKSVQNEENSRIINDL 1393 Query: 1342 XXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAK 1401 D++++++ K ++++ INE A+L+ N ++ Sbjct: 1394 KEFIKQYDEDIKSKDEKIKSIEQEKDAKINEIKAELETKETENSQLFGNISELQNMLSSR 1453 Query: 1402 VLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAI 1461 E + ++++ Q+ +L+++ ++F ++ L +Y++ + + + KE E Sbjct: 1454 DSEY-ETVCSDNNKLKQEIEALKSSLSEKENDFASI---LSKYDEEVSN--HNKEVE--- 1504 Query: 1462 LRLKMHENANHYETMQKESEIERVKL-IEELNVKITESVSLNKQVAELNKALEEEVAKTN 1520 L + N + +KE+EI +K IE L + E + ++++ ++A+++ Sbjct: 1505 -ELTKKDEENKQQVDEKENEISNLKKEIENLKSSLNEK---DNEISQNSQAIDDSSKHVQ 1560 Query: 1521 EMQ----TALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDN 1574 E+Q L+ ++ EI ++E++NL+ ++ S+I + + + ++E++ N Sbjct: 1561 ELQHQFDEDLKQKQEEISAKDEELSNLKKVLEEEKSEITSSLQEKDELIKQKEEEISN 1618 Score = 233 bits (571), Expect = 2e-59 Identities = 258/1153 (22%), Positives = 528/1153 (45%), Gaps = 93/1153 (8%) Query: 485 LKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTI 544 + QE++D KD +++++ E++ EE+ N +ID + + + +N + + + + Sbjct: 1 MNQEISD--KDKSIEEITERVNKLEEENKTKNSQIDEMKEQISSITTNEETAISTLNTQL 58 Query: 545 DNFSKVSDSNKEIVRLTE-ELHHLSQKVAELEEEKGNLQLHLVDY-----DSGRMIESDV 598 +N + D + ++ E E+ L++ V+E E+ LQ L ++ I+ + Sbjct: 59 NNKNNEIDLLHQQLQSKETEISKLTENVSEREKSFTELQEQLEKAKQEHEETISEIKLKL 118 Query: 599 YKKMIEMENLAETRLKAISLLES---QKFDLVQELHILQQKYDEVEDKLADI-SQLQSDQ 654 K E+ L T + S LE Q +L + L + +E+ D L+ + ++ + Sbjct: 119 ESKDNEINELNSTLSQIRSELEQTNKQNTELTETLSQKESNINEINDNLSKLREEISEKE 178 Query: 655 VCSEIKSVHLEE---QIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQ 711 KS +EE QI S KE+ I NL+ + +Q I++L+ E + N + Sbjct: 179 KTINEKSSKIEELNQQISEKDNSLKEMTEKINNLEEENKQKNSRIEELQQQLESLRNDDE 238 Query: 712 NYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESEL 771 N I +L ++L + + KI+EL + ++ K ++ +I+E+D I +E + Sbjct: 239 NRIN---NLYEELSQKES-KINELNELMMQQQTGKETILSQLNEQIKEKDSKIGELEENV 294 Query: 772 SKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLM 831 SK +S I + E +I + + ++ + + E QK S+ DEL ++ L Sbjct: 295 SKLESEISQKESNINELSSQVSEKDKMVNDISEEKNELQKQLSDQNSMIDELNEQIKELT 354 Query: 832 DHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTD-LAE 890 D+ L + E+ E KNQ L+ E + +S +++ + L E+ D L + Sbjct: 355 DN-------LSKSTTESTEKDSKNQELISEKET---EISHLKEEISKLTEQHGEKDKLIQ 404 Query: 891 SESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLE---IEFNTQIESAIRDKKVLN 947 + + QTQ +L+ I+ E Q L+ QK+ E+ + + EF ++E K LN Sbjct: 405 ELTEQIQTQDINLKQKDSNIS-ELQVLVSQKETELSEKDNSINEFIHKLEEKDLQIKELN 463 Query: 948 EKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQY 1007 E+ + +L AQ+ + +N+++ + V LE ++ + + Q + + Sbjct: 464 EQLNNKESQINELNAQISDKENSLQEITDKVH-----TLEETVQNKETEINQKNEELSER 518 Query: 1008 INEINKLNALLKQKDEEIIALNQKI--NNAQVSYMS-MVSDYESKLAQFTTKL-----EN 1059 +IN+LN ++ QKD EI N++I NN+++ ++ +S+ E+ L + T K+ +N Sbjct: 519 ETKINELNEIISQKDSEIQQKNEEISSNNSKIDELNQQISNKENSLQELTDKVHSLETKN 578 Query: 1060 MEEEMQ--RVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISST 1117 E+E Q ++K + + ++ N +LQ ++ ++ +IK+ K++K+ EMN ++ + Sbjct: 579 SEQETQIDELTKLVSEKEEENNKLQETIQTKETEIKD-KQSKVD-EMNQEISDK---DKS 633 Query: 1118 IEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQ 1177 IE +++ N ++ +K Q E + + + LNT+L K + Sbjct: 634 IEEITERVNKLEEENKTKNSQIDEMKEQISSITTNEETAI----STLNTQLN---NKNNE 686 Query: 1178 LETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISS---AVDQRGFE 1234 ++ L+ +L + N++ IN+L KL +L E N + + EL ISS + R + Sbjct: 687 IDLLHQQLQSKETENEKAINELNDKLNKLYEEIANKNTNITELNEQISSKNQEIVDRDNK 746 Query: 1235 IAELWKQHLAQREADFQKTEH---ELRVQLSAFESKYEQL---LDSVQSSTQEETNKIVT 1288 + L + L Q+ + ++ + E +S +S+ QL + + S +E N+I T Sbjct: 747 LQSLGTE-LNQKNEEIKEKDSKIGEFNDLVSKKDSEINQLQEEIADISSKIEELNNEIAT 805 Query: 1289 ME-QVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXX 1347 + + L NK+ +K+ +++L E+ + + ++ ++I D V + Sbjct: 806 KDASILELNNKIAEKDLKIKSLDEEKSSLQSKPAEKENDISDLLVKYDEKCSEIEAVQSE 865 Query: 1348 XXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDA-EAKVLELT 1406 + EN+ ++++ Q+I +EE ++ K +N EA E Sbjct: 866 LAKKDK-ENKEFEELMSQAISEKDEEISKSKNGISSLQEKLAEKEKEINSKNEANTAEKE 924 Query: 1407 HQLEL---KDSEI------YQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKES 1457 +L +D EI + + T + +FE+ +L+E + E EKE+ Sbjct: 925 ENSKLISQRDEEISNLNKSIDELRKEISTKDETISQFESKINELIEEISKKELTINEKET 984 Query: 1458 ELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVA 1517 ++A L ++ + N +++ ++ K I E+ ++TE K + EL + ++ + Sbjct: 985 KIAELNEQITQKENEINGLKEAEKVMETK-ISEIESQLTEK---EKSINELEETVQNKET 1040 Query: 1518 KTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMN 1577 + N+ L +E +I LN+ I+ + ++ + +I + S + Q Q+ N N Sbjct: 1041 EINQKNEELSERETKINELNEIISQKDSEIQQKNEEISSNNSKIDELNQ----QISNKEN 1096 Query: 1578 --KELLDAVPRAE 1588 +EL D V E Sbjct: 1097 SLQELTDKVHSLE 1109 Score = 228 bits (558), Expect = 8e-58 Identities = 312/1566 (19%), Positives = 683/1566 (43%), Gaps = 154/1566 (9%) Query: 144 VTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXX 203 ++ L+ IKEKD+ + L+ + +E+ I + INE + K+K Sbjct: 273 LSQLNEQIKEKDSKIGELEENVSKLESEISQKESNINELSSQVSEKDKMVNDISEEKNEL 332 Query: 204 XXXXX---XXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSL-EEANKL 259 ++ +Q+ ++ +N E ++ + + I K+ IS L EE +KL Sbjct: 333 QKQLSDQNSMIDELNEQIKELTDNLSKSTTESTEKDSKNQELISEKETEISHLKEEISKL 392 Query: 260 LEAARFEISLEHSKLAQEL-EQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEK-GSLE 317 E E KL QEL EQ +++ + S +++TE+ EK S+ Sbjct: 393 TEQHG-----EKDKLIQELTEQIQTQDINLKQKDSNISELQVLVS-QKETELSEKDNSIN 446 Query: 318 --IANMTELTKKI-ELLEHLN---CQIRQTNKEL---ENKLATMGTESKAVSSPSKKGSP 368 I + E +I EL E LN QI + N ++ EN L + + + + Sbjct: 447 EFIHKLEEKDLQIKELNEQLNNKESQINELNAQISDKENSLQEITDKVHTLEETVQNKET 506 Query: 369 LISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVI 428 I++K+ S+ ++ ++L+ +D++ + EI+ I LN+ + +KE + Sbjct: 507 EINQKN--EELSERETKINELNEIISQKDSEIQQKNEEISSNNSKIDELNQQISNKENSL 564 Query: 429 SEKDTXXXXXXXXXXGKDTLIAQL-QLEHQQHMEGPSLIH-VGTNTEDVNEIAKVQEQLK 486 E ++T I +L +L ++ E L + T ++ + +++ Sbjct: 565 QELTDKVHSLETKNSEQETQIDELTKLVSEKEEENNKLQETIQTKETEIKDKQSKVDEMN 624 Query: 487 QELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKL--------- 537 QE++D KD +++++ E++ EE+ N +ID + + + +N + + Sbjct: 625 QEISD--KDKSIEEITERVNKLEEENKTKNSQIDEMKEQISSITTNEETAISTLNTQLNN 682 Query: 538 ---------KQMQ-KTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVD 587 +Q+Q K +N +++ N ++ +L EE+ + + + EL E+ + +VD Sbjct: 683 KNNEIDLLHQQLQSKETENEKAINELNDKLNKLYEEIANKNTNITELNEQISSKNQEIVD 742 Query: 588 YDSG-RMIESDVYKKMIEMENLAETRLKAISLLESQKFD----LVQELHILQQKYDEVED 642 D+ + + +++ +K E++ ++++ + L S+K L +E+ + K +E+ + Sbjct: 743 RDNKLQSLGTELNQKNEEIKE-KDSKIGEFNDLVSKKDSEINQLQEEIADISSKIEELNN 801 Query: 643 KLA--DISQLQSDQVCSE--IKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTI-- 696 ++A D S L+ + +E +K L+E+ +L + E I +L + ++ I Sbjct: 802 EIATKDASILELNNKIAEKDLKIKSLDEEKSSLQSKPAEKENDISDLLVKYDEKCSEIEA 861 Query: 697 -------KDLENDK-EDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQ 748 KD EN + E++M++ + E + + EK++E +IN + ++ Sbjct: 862 VQSELAKKDKENKEFEELMSQAISEKDEEISKSKNGISSLQEKLAEKEKEINSKNEANTA 921 Query: 749 TQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQE 808 + I +RD I N+ + + + I +E+I+ E + L + + + E Sbjct: 922 EKEENSKLISQRDEEISNLNKSIDELRKEISTKDETISQFESKINELIEEISKKELTINE 981 Query: 809 KQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQIS 868 K+ +E Q + N + L + ++V+E ++ EIE + E +K L E QN + Sbjct: 982 KETKIAELNEQITQKENEINGLKEAEKVMETKISEIESQLTEKEKSINELEETVQNKETE 1041 Query: 869 LSDMQQHYNALVEKANR-TDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIED 927 ++ + + K N ++ + ++ Q + ++ SN +I +Q I K+ +++ Sbjct: 1042 INQKNEELSERETKINELNEIISQKDSEIQQKNEEISSNNSKIDELNQQ-ISNKENSLQE 1100 Query: 928 LEIEF------NTQIESAIRD-KKVLNEKYEKN---IEYVTQLEAQLQEYKNNIENLNMN 977 L + N++ E+ I + K+++EK E+N E + E ++++ ++ ++ +N Sbjct: 1101 LTDKVHSLETKNSEQETQIEELTKLVSEKEEENNKLQETIQTKETEIKDKQSKVDEMNQE 1160 Query: 978 VEELNKMNLELIDKHVQK-------QQTQSPDYTEQY----INE---INKLNALLKQKDE 1023 + + +K ++E I + V K + +Q + EQ NE I+ LN L K+ Sbjct: 1161 ISDKDK-SIEEITERVNKLEEENKTKNSQIDEMKEQISSITTNEETAISTLNTQLNNKNN 1219 Query: 1024 EIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSK--QLLDSKQH---- 1077 EI L+Q++ + + + + + TK ++E+ ++++ ++ K+ Sbjct: 1220 EIDLLHQQLQSKETEIKQLNEEISERNNALQTKETEIKEKELKINELNDIISKKEEEKAE 1279 Query: 1078 -----NEELQILVREQDDQIKELKETKLTFEMNIP---------KTEGMIISSTIEPM-- 1121 NE + L E++ QI EL E L E + K +S I+ M Sbjct: 1280 KESLLNENINKLNTERESQINELSEKLLKLEEQLKQETLSNEDMKQTNTSLSQKIDEMAF 1339 Query: 1122 --SDDANNVDXXXXXXXXXXXXLK-----VQEEEEFIQERSVLQEQSAKLNTELQECYTK 1174 SD + + + V + +E I+E+SV E+++++ +L+E + Sbjct: 1340 QLSDKTSQLQELNQQITVLSSQISDKDKTVNDLQEEIKEKSVQNEENSRIINDLKEFIKQ 1399 Query: 1175 IIQ-LETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISS------- 1226 + +++ + ++ + +IN++K++LE TEN L ++EL++ +SS Sbjct: 1400 YDEDIKSKDEKIKSIEQEKDAKINEIKAELETKETENSQLFGNISELQNMLSSRDSEYET 1459 Query: 1227 --AVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQ---E 1281 + + + + E K L+++E DF + ++S + E+L + + Q E Sbjct: 1460 VCSDNNKLKQEIEALKSSLSEKENDFASILSKYDEEVSNHNKEVEELTKKDEENKQQVDE 1519 Query: 1282 ETNKIVTM-EQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIED------EKVA- 1333 + N+I + +++ +L++ L +K+ + + D ++ L+ + ++ E+++ Sbjct: 1520 KENEISNLKKEIENLKSSLNEKDNEISQNSQAIDDSSKHVQELQHQFDEDLKQKQEEISA 1579 Query: 1334 ----FXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXX 1389 L+ +++ KQ +E+ I N+N + +K Sbjct: 1580 KDEELSNLKKVLEEEKSEITSSLQEKDELIKQ-KEEEISNLNSVIQEKEKVIASLQGKVN 1638 Query: 1390 XXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIE 1449 VN EA+++ L + K+ EI + T+ ++ E ++ + + +K I Sbjct: 1639 DENNEVNAKEAEIVSLNEIQKKKEEEISSLQEKLNSTIAEKEKEISELQSSINDKDKEIS 1698 Query: 1450 DLTYEKESELAILRLKMHE-NANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAEL 1508 L + E + K E ++ + + QK+ EI +K E+ K E L V E Sbjct: 1699 SLQEKVNIENNDVNTKETEISSLNDQLKQKDEEINNLK--SEIKEKFEELSKLQSLVNEN 1756 Query: 1509 NKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGR 1568 + + K N + N+E E+ +EI+NL ++ +I +++ + Sbjct: 1757 EQVIVSLQEKVNSDEI---NKENELKMKEEEISNLNGSIQEKEKEISLLKENFNNSLAQK 1813 Query: 1569 DEQLDN 1574 DE++ N Sbjct: 1814 DEEISN 1819 Score = 207 bits (506), Expect = 2e-51 Identities = 280/1494 (18%), Positives = 637/1494 (42%), Gaps = 103/1494 (6%) Query: 169 ETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAM 228 + +I ++ E++N+ ++ + KN Q+ + Sbjct: 9 DKSIEEITERVNKLEEENKTKNSQIDEMKEQISSITTNEETAISTLNTQLNNKNNEIDLL 68 Query: 229 EAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXX 288 + + ++ + K E+ R S E + LE A+ E S++ +LE Sbjct: 69 HQQLQSKETEISKLTENVSEREKSFTELQEQLEKAKQEHEETISEIKLKLESKDNEINEL 128 Query: 289 XXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENK 348 + + +E + ++ TE+ E S + +N+ E+ + L + +T E +K Sbjct: 129 NSTLSQI-RSELEQTNKQNTELTETLSQKESNINEINDNLSKLREEISEKEKTINEKSSK 187 Query: 349 LATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINK--NE 406 + + + + K+ + I+ N + Q E+L D + +IN E Sbjct: 188 IEELNQQISEKDNSLKEMTEKINNLEEENKQKNSRIEELQQQLESLRNDDENRINNLYEE 247 Query: 407 IAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLI 466 +++ E I LN+ ++ ++ + K+T KD+ I +L+ E+ +E Sbjct: 248 LSQKESKINELNELMMQQQ---TGKETILSQLNEQIKEKDSKIGELE-ENVSKLES---- 299 Query: 467 HVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNM 526 + ++NE++ + + +ND ++ N +L ++L I +LN++I N+ Sbjct: 300 EISQKESNINELSSQVSEKDKMVNDISEEKN--ELQKQLSDQNSMIDELNEQIKELTDNL 357 Query: 527 IKVKSNHKLKLKQMQKTI-DNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHL 585 K + K + Q+ I + +++S +EI +LTE+ + + EL E+ ++L Sbjct: 358 SKSTTESTEKDSKNQELISEKETEISHLKEEISKLTEQHGEKDKLIQELTEQIQTQDINL 417 Query: 586 VDYDSG----RMIESDVYKKMIEMEN--------LAETRLKAISL------LESQKFDLV 627 DS +++ S ++ E +N L E L+ L ESQ +L Sbjct: 418 KQKDSNISELQVLVSQKETELSEKDNSINEFIHKLEEKDLQIKELNEQLNNKESQINELN 477 Query: 628 QELHILQQKYDEVEDKLADISQ-LQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLK 686 ++ + E+ DK+ + + +Q+ + K+ L E+ ++ + ++ ++ Sbjct: 478 AQISDKENSLQEITDKVHTLEETVQNKETEINQKNEELSERETKINELNEIISQKDSEIQ 537 Query: 687 LDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEK---ISELLAKINHEE 743 E++ ++ + I NK +N +QE D LE ++E+ I EL ++ +E Sbjct: 538 QKNEEISSNNSKIDELNQQISNK-ENSLQELTDKVHSLETKNSEQETQIDELTKLVSEKE 596 Query: 744 QSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLG 803 + + Q IQ ++ I++ +S++ + I ++SI + +R LE + Sbjct: 597 EENNKLQ----ETIQTKETEIKDKQSKVDEMNQEISDKDKSIEEITERVNKLEEENKTKN 652 Query: 804 SYLQEKQKAYSEYTIQEDELVNRLAVLMDHDR----VVEKQLLEIEHENK----ELQKKN 855 S + E ++ S T E+ ++ L +++ ++ +QL E EN+ EL K Sbjct: 653 SQIDEMKEQISSITTNEETAISTLNTQLNNKNNEIDLLHQQLQSKETENEKAINELNDKL 712 Query: 856 QILLEENQNLQISLSDMQQHYNA----LVEKANRTDLAESESTKYQTQLRDLESNLKR-- 909 L EE N +++++ + ++ +V++ N+ +E + ++++ +S + Sbjct: 713 NKLYEEIANKNTNITELNEQISSKNQEIVDRDNKLQSLGTELNQKNEEIKEKDSKIGEFN 772 Query: 910 -ITHEHQTLIVQKKKEIEDLEIEFNT-QIESAIRDKKVL---NEKYEKNI------EYVT 958 + + + I Q ++EI D+ + E A +D +L N+ EK++ E + Sbjct: 773 DLVSKKDSEINQLQEEIADISSKIEELNNEIATKDASILELNNKIAEKDLKIKSLDEEKS 832 Query: 959 QLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALL 1018 L+++ E +N+I +L + +E +E + + K+ ++ ++ E I++ + + Sbjct: 833 SLQSKPAEKENDISDLLVKYDE-KCSEIEAVQSELAKKDKENKEFEELMSQAISEKDEEI 891 Query: 1019 KQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHN 1078 + I +L +K+ + S ++ + + + +EE+ ++K + + ++ Sbjct: 892 SKSKNGISSLQEKLAEKEKEINSKNEANTAEKEENSKLISQRDEEISNLNKSIDELRKEI 951 Query: 1079 EELQILVREQDDQIKELKETKLTFEMNIPKTEGMI--ISSTIEPMSDDANNVDXXXXXXX 1136 + + + +I EL E E+ I + E I ++ I ++ N + Sbjct: 952 STKDETISQFESKINELIEEISKKELTINEKETKIAELNEQITQKENEINGLKEAEKVME 1011 Query: 1137 XXXXXLKVQ--EEEEFIQE-RSVLQEQSAKLNT---ELQECYTKIIQLETLNTELTGHDV 1190 ++ Q E+E+ I E +Q + ++N EL E TKI +L + ++ Sbjct: 1012 TKISEIESQLTEKEKSINELEETVQNKETEINQKNEELSERETKINELNEIISQKDSEIQ 1071 Query: 1191 VNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADF 1250 E+I+ SK+++LN + N +++ EL + S + + ++ + L + ++ Sbjct: 1072 QKNEEISSNNSKIDELNQQISNKENSLQELTDKVHSLETKNSEQETQI--EELTKLVSEK 1129 Query: 1251 QKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQD----KEEHL 1306 ++ ++L+ + E++ + V QE ++K ++E++T NKL++ K + Sbjct: 1130 EEENNKLQETIQTKETEIKDKQSKVDEMNQEISDKDKSIEEITERVNKLEEENKTKNSQI 1189 Query: 1307 RNLQEKYADVINQ----IEILRSEIEDE--KVAFXXXXXXXXXXXXXXXXDLRTENQSYK 1360 ++E+ + + I L +++ ++ ++ + +E + Sbjct: 1190 DEMKEQISSITTNEETAISTLNTQLNNKNNEIDLLHQQLQSKETEIKQLNEEISERNNAL 1249 Query: 1361 QMQEQSI----LNINEENAQLKKSSXXXXXXXXXXXXRVN----DAEAKVLELTHQLELK 1412 Q +E I L INE N + K +N + E+++ EL+ +L Sbjct: 1250 QTKETEIKEKELKINELNDIISKKEEEKAEKESLLNENINKLNTERESQINELSEKLLKL 1309 Query: 1413 DSEIYQKT---HEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHEN 1469 + ++ Q+T + T T + + + + QL + ++++L ++ + L+ + Sbjct: 1310 EEQLKQETLSNEDMKQTNTSLSQKIDEMAFQLSDKTSQLQELN-QQITVLSSQISDKDKT 1368 Query: 1470 ANHYETMQKESEI---ERVKLIEELNVKITESVSLNKQVAELNKALEEEV-AKTNEMQTA 1525 N + KE + E ++I +L I + K E K++E+E AK NE++ Sbjct: 1369 VNDLQEEIKEKSVQNEENSRIINDLKEFIKQYDEDIKSKDEKIKSIEQEKDAKINEIKAE 1428 Query: 1526 LENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKE 1579 LE +E E L I+ LQNM+ + S+ + S + KQ + + KE Sbjct: 1429 LETKETENSQLFGNISELQNMLSSRDSEYETVCSDNNKLKQEIEALKSSLSEKE 1482 Score = 200 bits (488), Expect = 3e-49 Identities = 263/1338 (19%), Positives = 602/1338 (44%), Gaps = 112/1338 (8%) Query: 298 QSIEPSCEEKTEIEEKGSLEIANMTELTKKIE-LLEHLNCQIRQTNKELENKLATMGTES 356 +SIE E ++EE+ + + + E+ ++I + + I N +L NK + Sbjct: 10 KSIEEITERVNKLEEENKTKNSQIDEMKEQISSITTNEETAISTLNTQLNNKNNEIDLLH 69 Query: 357 KAVSSPSKKGSPLISRKSGRNTA-SKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQ 415 + + S + S L S R + ++++ + E +++T +I K ++ + I Sbjct: 70 QQLQSKETEISKLTENVSEREKSFTELQEQLEKAKQE--HEETISEI-KLKLESKDNEIN 126 Query: 416 SLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDV 475 LN L + + + K++ I ++ + E + + + Sbjct: 127 ELNSTLSQIRSELEQTNKQNTELTETLSQKESNINEINDNLSKLRE-----EISEKEKTI 181 Query: 476 NEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKL 535 NE + E+L Q++++ KD ++K++ EK+ + EE+ Q N I+ + + ++++ + Sbjct: 182 NEKSSKIEELNQQISE--KDNSLKEMTEKINNLEEENKQKNSRIEELQQQLESLRNDDEN 239 Query: 536 KLKQMQKTIDNF-SKVSDSNKEIVRLTEE----LHHLSQKVAELEEEKGNLQLHLVDYDS 590 ++ + + + SK+++ N+ +++ L L++++ E + + G L+ ++ Sbjct: 240 RINNLYEELSQKESKINELNELMMQQQTGKETILSQLNEQIKEKDSKIGELE------EN 293 Query: 591 GRMIESDVYKK---MIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADI 647 +ES++ +K + E+ + + K ++ + +K +L ++L DE+ +++ ++ Sbjct: 294 VSKLESEISQKESNINELSSQVSEKDKMVNDISEEKNELQKQLSDQNSMIDELNEQIKEL 353 Query: 648 SQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIM 707 + S + +++ +S + E++ + E + EQ +K+ ++ Sbjct: 354 TDNLSKSTTESTEKDSKNQEL--ISEKETEISHLKEEISKLTEQ--------HGEKDKLI 403 Query: 708 NKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENI 767 +L IQ D+ K + + ++ L+++ E K + K++E+DL I+ + Sbjct: 404 QELTEQIQ-TQDINLKQKDSNISELQVLVSQKETELSEKDNSINEFIHKLEEKDLQIKEL 462 Query: 768 ESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRL 827 +L+ +S+I L I+ D+ SL+ D++ + + Q +E + +EL R Sbjct: 463 NEQLNNKESQINELNAQIS---DKENSLQEITDKVHTLEETVQNKETEINQKNEELSERE 519 Query: 828 AVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTD 887 + + + ++ ++ EI+ +N+E+ N + E NQ + + +Q+ L +K + + Sbjct: 520 TKINELNEIISQKDSEIQQKNEEISSNNSKIDELNQQISNKENSLQE----LTDKVHSLE 575 Query: 888 LAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEI---EFNTQIESAIRDKK 944 SE +L L S + ++ Q I K+ EI+D + E N +I + + Sbjct: 576 TKNSEQETQIDELTKLVSEKEEENNKLQETIQTKETEIKDKQSKVDEMNQEISDKDKSIE 635 Query: 945 VLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEE-LNKMNLELIDKHVQ----KQQTQ 999 + E+ K E +Q+ E K I ++ N E ++ +N +L +K+ + QQ Q Sbjct: 636 EITERVNKLEEENKTKNSQIDEMKEQISSITTNEETAISTLNTQLNNKNNEIDLLHQQLQ 695 Query: 1000 SPDY-TEQYINEIN-KLNALLKQ---KDEEIIALNQKINNAQVSYMSMVSDYESKLAQFT 1054 S + E+ INE+N KLN L ++ K+ I LN++I++ + D ++KL Sbjct: 696 SKETENEKAINELNDKLNKLYEEIANKNTNITELNEQISSKNQE----IVDRDNKLQSLG 751 Query: 1055 TKLENMEEEMQRVSKQL-----LDSKQHNE--ELQILVREQDDQIKELKETKLTFEMNIP 1107 T+L EE++ ++ L SK+ +E +LQ + + +I+EL T + +I Sbjct: 752 TELNQKNEEIKEKDSKIGEFNDLVSKKDSEINQLQEEIADISSKIEELNNEIATKDASIL 811 Query: 1108 KTEGMIISST--IEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQE--QSAK 1163 + I I+ + ++ +++ L V+ +E+ + +V E + K Sbjct: 812 ELNNKIAEKDLKIKSLDEEKSSLQSKPAEKENDISDLLVKYDEKCSEIEAVQSELAKKDK 871 Query: 1164 LNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSS 1223 N E +E ++ I + + + + + ++ +L K +++N++N+ + AE + Sbjct: 872 ENKEFEELMSQAISEKDEEISKSKNGISSLQE--KLAEKEKEINSKNE---ANTAEKEEN 926 Query: 1224 ISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQS---STQ 1280 S + QR EI+ L K R+ K E +S FESK +L++ + + Sbjct: 927 -SKLISQRDEEISNLNKSIDELRKEISTKDE-----TISQFESKINELIEEISKKELTIN 980 Query: 1281 EETNKIVTM-EQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXX 1339 E+ KI + EQ+T +N++ +E + ++ K +++ +Q+ I +E Sbjct: 981 EKETKIAELNEQITQKENEINGLKEAEKVMETKISEIESQLTEKEKSI-NELEETVQNKE 1039 Query: 1340 XXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAE 1399 + T+ ++ Q I ++N ++ ++ + N + Sbjct: 1040 TEINQKNEELSERETKINELNEIISQKDSEIQQKNEEISSNNSKIDELNQQISNKENSLQ 1099 Query: 1400 AKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESEL 1459 ++ + H LE K+SE + E T ++++ +E +++ + E I+D K+S++ Sbjct: 1100 -ELTDKVHSLETKNSEQETQIEELTKLVSEKEEENNKLQETIQTKETEIKD----KQSKV 1154 Query: 1460 AILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKT 1519 +M++ E K+ IE + E +N E+ + N Q+ E+ + + T Sbjct: 1155 D----EMNQ-----EISDKDKSIEEIT--ERVNKLEEENKTKNSQIDEMKEQISS--ITT 1201 Query: 1520 NEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQ---KHVSFASDTKQGRDEQLDNTM 1576 NE +TA+ ++ N+EI L +++ ++I+ + +S ++ Q ++ ++ Sbjct: 1202 NE-ETAISTLNTQLNNKNNEIDLLHQQLQSKETEIKQLNEEISERNNALQTKETEIKEKE 1260 Query: 1577 NK--ELLDAVPRAELDLA 1592 K EL D + + E + A Sbjct: 1261 LKINELNDIISKKEEEKA 1278 Score = 193 bits (470), Expect = 4e-47 Identities = 320/1544 (20%), Positives = 664/1544 (43%), Gaps = 164/1544 (10%) Query: 151 IKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXX 210 IK+K+ +S L ++ E I LQ K+N+++ + AK Sbjct: 1609 IKQKEEEISNLNSVIQEKEKVIASLQGKVNDENNEVNAKEAEIVSLNEIQ---------- 1658 Query: 211 XEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEA----NKLLEAARFE 266 + +++++ +QE + AE + E L I KD ISSL+E N + E Sbjct: 1659 -KKKEEEISSLQEKLNSTIAEKEKEISELQSSINDKDKEISSLQEKVNIENNDVNTKETE 1717 Query: 267 ISLEHSKLAQELEQXXXXXXXXXXXXXXLAK-QSIEPSCEEK-TEIEEK-GSLEIANMTE 323 IS + +L Q+ E+ L+K QS+ E+ ++EK S EI E Sbjct: 1718 ISSLNDQLKQKDEEINNLKSEIKEKFEELSKLQSLVNENEQVIVSLQEKVNSDEINKENE 1777 Query: 324 LTKKIELLEHLNCQIRQTNKEL----ENKLATMGTESKAVSSPSKKGSPLISRKSGRNTA 379 L K E + +LN I++ KE+ EN ++ + + +S+ K L KSG Sbjct: 1778 LKMKEEEISNLNGSIQEKEKEISLLKENFNNSLAQKDEEISNLKKV---LEEEKSG--IT 1832 Query: 380 SKMKSPWSQLSSETLNQDTDKKINKNEIA-----KLEMVIQS------LNKDLVDKEYVI 428 S ++ S+L SE +D +K + EI KLE++ Q LN L + ++ Sbjct: 1833 SSLQEQISKLQSEIKERDEIQKKKEEEIQTLSNEKLELLKQKEEEINVLNSKLNESVELL 1892 Query: 429 SEKD---TXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQ- 484 +K+ K+ I++LQ E L E +NE K +++ Sbjct: 1893 KQKEGDNENNDKISEIRQQKEKEISELQSEINSLKN--ELSANKEEMEKLNETIKERDEE 1950 Query: 485 ---LKQELNDEIKDVN-----VKDLIEKLK-------------SAEEQITQLNDEIDAAN 523 +KQ+ +D+ +VN + D+ +KL S E ++ I + Sbjct: 1951 ISSIKQKADDDKSEVNSISNILSDIKQKLSNQTQESIKEGRVFSKEREVPDEETNISQLD 2010 Query: 524 KNMIKVKSNHKLKLKQMQKTIDNF--SKVSDSNKEIVRLTEELHHLSQKVAELEEEKG-- 579 + IK K + +K +++ + +D ++ +D + L+E + + + EL++E Sbjct: 2011 YSPIKSKPSEVVKSREVIELVDEDEGNETNDIRSTVEYLSETIDEMQANIEELKKENAKK 2070 Query: 580 ----------NLQLHLVDYDSGRMIESDVYKKMIEMEN----LAETRLKAISLLESQKFD 625 N QL ++ DS + + + M+ M N L E K + SQ D Sbjct: 2071 SQEKQSLIYQNQQLRIL-LDSAEIEMNKKSQGMMTMMNDKNGLIENLTKELQTTRSQLND 2129 Query: 626 LVQE-LHILQQKYDEVEDKLADISQLQSDQVC-SEIKSVHLEEQIDALSASKKELALVIE 683 + Q+ ++ +QQ+ + ++ ++ L S ++ +E Q DA++ + +E +I Sbjct: 2130 IKQQAVYQMQQQKSFDDQEIQRLNGLISQKLSENEQMRQQFNLQADAMNKTIQEKDEMIN 2189 Query: 684 NLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEE 743 +K +L N+K + + LQN +EN + + E + S+L I + + Sbjct: 2190 QIKTRANKLL-------NEKLNENSNLQNLQKENEEKLSQKENELNQIKSQLNTVIQNAQ 2242 Query: 744 Q--SKIQTQ-FGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKAD 800 S +Q + I+ K+++++ I+N++ L+ S E+S++++E LE+ Sbjct: 2243 SQISALQNEKIAIENKMKQQEDLIQNMK--LANESS-----EQSLSLLEGENSKLEQICA 2295 Query: 801 QLGSYLQE---KQKA-YSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQ 856 L +E K KA ++EY ++ + +R +L ++++ + I +N+ +N Sbjct: 2296 NLKKSKEEEIEKMKAMFNEYKVKV--MQDRTEILSQNEQLKQNY---ISLQNELASSRNN 2350 Query: 857 ILLEENQNLQISLSDMQQHYNALVEKANRT-DLAESESTKYQTQLRDLESNLKRITHEHQ 915 L E +LQ ++D+Q + + KAN + + + QT+ +L++N ++ +E Q Sbjct: 2351 --LSEINSLQSKVNDLQNENSNIKSKANSMLSSMQQKINELQTENINLKNNQSQL-NELQ 2407 Query: 916 TLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLN 975 + ++ +LE E T+ ++ LNE N + + L N ++ Sbjct: 2408 NSNNSLQTKLNELEKENETKNSEISSLQQKLNELQNDNTTIKNKANSILNSLNNQLKESQ 2467 Query: 976 MNVEELNKMN--LELIDKHVQKQQTQSPDYTEQYINEINKLNAL---LKQKDEEIIALNQ 1030 + EL N ++ ++ + QT++ Q IN LN+ L+ + +EI L Sbjct: 2468 TKLNELQNENTSIKTLETQIHSLQTENETIKSQSQETINSLNSRISELQNQIQEISQLQS 2527 Query: 1031 KINNAQVSYMSM-------VSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQH-NEELQ 1082 ++N+ + S+ + Y SK+++ + + + +++S+ L Q+ N+ L+ Sbjct: 2528 ELNDLKTENQSLHEKISELTNSYNSKISELQIENQEILSSKEQISQSKLSELQNENQSLK 2587 Query: 1083 ILVREQDDQIKEL--KETKLTFEMNIPKTEGMI-ISSTIEPMSDDANNVDXXXXXXXXXX 1139 + + E++++ ++L ++L ++++ K + IS +++ +D Sbjct: 2588 LQISEKEEENEKLMNSNSELMNQIDLVKEDTKKEISHLQATINEKQTKIDGLNSQISQNE 2647 Query: 1140 XXL--KVQEEEEFIQERS----VLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQ 1193 K++ + I E +L+++ + L ++L+ ++ET N++ + Sbjct: 2648 EERIGKLESLQSTIDEDKSQIEILEQKVSDLESKLENLQKHYSEIETKNSQYENFISKAR 2707 Query: 1194 EQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKT 1253 N+ K+K+ QL TEN++L V ++ISS Q I+++ +++ E Q Sbjct: 2708 VAFNENKAKISQLETENNSLKEKVVNYENAISSNDSQLKNFISQMKEENSKLEEEKSQLI 2767 Query: 1254 EHELRVQLSAFESKYEQLLDSVQSSTQEETN-KIVTMEQVTSLQNKLQDKEEHLRNLQEK 1312 + R+ E + +Q + + ++ T T E+ T L + + EE ++ L+++ Sbjct: 2768 KENQRI--PQLEEENKQFANQLSKFNEKLTQIDRETEEEKTKLLTEKSNLEEEIKQLKQQ 2825 Query: 1313 YADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINE 1372 ++ N+ L + + K D + + +++EQ I Sbjct: 2826 NEEINNEKVQLEEQFSNAKSKLAEEINQIKKPNEEINNDQSNKEEEKSKLREQ-INEFLN 2884 Query: 1373 ENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQ------KTHEYTIT 1426 E L++ +N+ + + ++ +++L +++ Q E Sbjct: 2885 ERTHLQEQIHQISNEKSQLQEELNEVKKQNEKINEEIQLLNNDKSQLQEDKSALEEVLKQ 2944 Query: 1427 LTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERV- 1485 + Q+ND+ + + YEK+I DL K SEL + E + + ES IE++ Sbjct: 2945 MEQQNDQ-SSTEEMKSNYEKQINDL-QSKVSELENKLISQTEEKSQIANL--ESVIEKLR 3000 Query: 1486 ---KLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQ------EIEIVTL 1536 K IEE +K + V + AE N E+++ + L+ Q +I L Sbjct: 3001 NENKNIEEEKLKFEKQVKDLQTNAETNDQREDKITELKLRNAELQQQMKDYQNNSQINLL 3060 Query: 1537 NDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKEL 1580 ++I +LQ+ + A K ++ ++ S TK +++ +N+++ Sbjct: 3061 QNQIKDLQSQISAQKQKYEEQIN--SQTKNEEEDEGIEVVNRDI 3102 Score = 186 bits (454), Expect = 3e-45 Identities = 288/1479 (19%), Positives = 639/1479 (43%), Gaps = 148/1479 (10%) Query: 147 LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXX 206 +S I EKD +S K K I LQEK+ EK++ I +KN+A T Sbjct: 880 MSQAISEKDEEIS----KSK---NGISSLQEKLAEKEKEINSKNEANTAEKEENSKLISQ 932 Query: 207 XXXXXEDTKQQMTKMQENFIAME---AEWKDEKQRLLKDIESKDVRISSLEEANKLL--E 261 + + + ++++ + ++++ + L+++I K++ I+ E L + Sbjct: 933 RDEEISNLNKSIDELRKEISTKDETISQFESKINELIEEISKKELTINEKETKIAELNEQ 992 Query: 262 AARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEK-TEIEEKGSLEIAN 320 + E + K A+++ + + +E + + K TEI +K Sbjct: 993 ITQKENEINGLKEAEKVMETKISEIESQLTEKEKSINELEETVQNKETEINQKNEELSER 1052 Query: 321 MTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTAS 380 T++ + E++ + +I+Q N+E+ + + + ++ +S+ L + T Sbjct: 1053 ETKINELNEIISQKDSEIQQKNEEISSNNSKIDELNQQISNKENSLQELTDKVHSLET-- 1110 Query: 381 KMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXX 440 K+ + E L + +K +N KL+ IQ+ ++ DK+ + E + Sbjct: 1111 --KNSEQETQIEELTKLVSEKEEENN--KLQETIQTKETEIKDKQSKVDEMNQEISDKDK 1166 Query: 441 XXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVK- 499 + +L+ E++ + E ++ I +E LN ++ + N + Sbjct: 1167 SIEEITERVNKLEEENKTKNS-----QIDEMKEQISSITTNEETAISTLNTQLNNKNNEI 1221 Query: 500 DLI-EKLKSAEEQITQLNDEIDAANKNMIKVKSNH----KLKLKQMQKTI-----DNFSK 549 DL+ ++L+S E +I QLN+EI N N ++ K +LK+ ++ I + K Sbjct: 1222 DLLHQQLQSKETEIKQLNEEISERN-NALQTKETEIKEKELKINELNDIISKKEEEKAEK 1280 Query: 550 VSDSNKEIVRLTEE----LHHLSQKVAELEEEK-----GNLQLHLVDYDSGRMIESDVYK 600 S N+ I +L E ++ LS+K+ +LEE+ N + + + I+ ++ Sbjct: 1281 ESLLNENINKLNTERESQINELSEKLLKLEEQLKQETLSNEDMKQTNTSLSQKIDEMAFQ 1340 Query: 601 KMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSD------Q 654 + L E + I++L SQ D + ++ LQ++ E + + S++ +D Q Sbjct: 1341 LSDKTSQLQELN-QQITVLSSQISDKDKTVNDLQEEIKEKSVQNEENSRIINDLKEFIKQ 1399 Query: 655 VCSEIKSVHLEEQIDALSASK----KELALVIENLKLDKEQLYGTIKDLENDKEDIMNKL 710 +IKS +E+I ++ K E+ +E + + QL+G I +L+N ++ Sbjct: 1400 YDEDIKSK--DEKIKSIEQEKDAKINEIKAELETKETENSQLFGNISELQNMLSSRDSEY 1457 Query: 711 QNYIQENMDLTDKLEKMSA---EK---ISELLAKINHEEQSKIQTQFGIDAKIQERDLYI 764 + +N L ++E + + EK + +L+K + E + + + K +E + Sbjct: 1458 ETVCSDNNKLKQEIEALKSSLSEKENDFASILSKYDEEVSNHNKEVEELTKKDEENKQQV 1517 Query: 765 ENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELV 824 + E+E+S K I L+ S+ ++ + D ++QE Q + E Q+ E + Sbjct: 1518 DEKENEISNLKKEIENLKSSLNEKDNEISQNSQAIDDSSKHVQELQHQFDEDLKQKQEEI 1577 Query: 825 N-RLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKA 883 + + L + +V+E++ EI LQ+K++++ ++ + + S +Q+ + Sbjct: 1578 SAKDEELSNLKKVLEEEKSEI---TSSLQEKDELIKQKEEEISNLNSVIQEKEKVIASLQ 1634 Query: 884 NRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDK 943 + + +E + ++ L K+ E +L + I + E E + +++S+I DK Sbjct: 1635 GKVNDENNEVNAKEAEIVSLNEIQKKKEEEISSLQEKLNSTIAEKEKEIS-ELQSSINDK 1693 Query: 944 KVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVE--ELNKMNLELIDKHVQKQQTQSP 1001 +K I + LQE K NIEN ++N + E++ +N +L K + +S Sbjct: 1694 -------DKEI-------SSLQE-KVNIENNDVNTKETEISSLNDQLKQKDEEINNLKS- 1737 Query: 1002 DYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENME 1061 + E++ E++KL +L+ + ++ I++L +K+N+ +++ + + E +++ ++ E Sbjct: 1738 EIKEKF-EELSKLQSLVNENEQVIVSLQEKVNSDEINKENELKMKEEEISNLNGSIQEKE 1796 Query: 1062 EEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPM 1121 +E+ + + +S + ++D++I LK+ + I + + I + Sbjct: 1797 KEISLLKENFNNS----------LAQKDEEISNLKKVLEEEKSGITSS----LQEQISKL 1842 Query: 1122 SDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETL 1181 + D L ++ E Q+ + ++KLN ++ K E Sbjct: 1843 QSEIKERDEIQKKKEEEIQTLSNEKLELLKQKEEEINVLNSKLNESVELLKQKEGDNEN- 1901 Query: 1182 NTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQ 1241 N +++ +++I++L+S++ L E LS E ++ + +R EI+ + Sbjct: 1902 NDKISEIRQQKEKEISELQSEINSLKNE----LSANKEEMEKLNETIKERDEEISSI--- 1954 Query: 1242 HLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQD 1301 +++AD K+E + +L ++ +T + + +V S + ++ D Sbjct: 1955 ---KQKADDDKSE----------VNSISNILSDIKQKLSNQTQESIKEGRVFSKEREVPD 2001 Query: 1302 KEEHLRNL-----QEKYADVINQIEILRSEIEDEK------VAFXXXXXXXXXXXXXXXX 1350 +E ++ L + K ++V+ E++ EDE + Sbjct: 2002 EETNISQLDYSPIKSKPSEVVKSREVIELVDEDEGNETNDIRSTVEYLSETIDEMQANIE 2061 Query: 1351 DLRTENQSYKQMQEQSILNINEE-NAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQL 1409 +L+ EN + K ++QS++ N++ L + +ND + LT +L Sbjct: 2062 ELKKEN-AKKSQEKQSLIYQNQQLRILLDSAEIEMNKKSQGMMTMMNDKNGLIENLTKEL 2120 Query: 1410 ELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHEN 1469 + S++ + + Q+ F++ Q++ +R+ L +K SE +R + + Sbjct: 2121 QTTRSQL-NDIKQQAVYQMQQQKSFDD--QEI----QRLNGLISQKLSENEQMRQQFNLQ 2173 Query: 1470 ANHY-ETMQKESE-IERVKLIEELNVKITESVSLNKQVAELNKALEEEVA-KTNEMQTAL 1526 A+ +T+Q++ E I ++K N + E ++ N + L K EE+++ K NE+ Sbjct: 2174 ADAMNKTIQEKDEMINQIK--TRANKLLNEKLNENSNLQNLQKENEEKLSQKENELNQIK 2231 Query: 1527 ENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTK 1565 I +I+ LQN A +K+++ + K Sbjct: 2232 SQLNTVIQNAQSQISALQNEKIAIENKMKQQEDLIQNMK 2270 Score = 163 bits (395), Expect = 5e-38 Identities = 228/1155 (19%), Positives = 534/1155 (46%), Gaps = 105/1155 (9%) Query: 152 KEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXX 211 +++ N + ++ ++ + TI ++Q I E ++ +N + Sbjct: 2033 EDEGNETNDIRSTVEYLSETIDEMQANIEE----LKKENAKKSQEKQSLIYQNQQLRILL 2088 Query: 212 EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271 + + +M K + + M ++K L++++ +K+++ ++ + N + + A +++ + Sbjct: 2089 DSAEIEMNKKSQGMMTM----MNDKNGLIENL-TKELQ-TTRSQLNDIKQQAVYQMQQQK 2142 Query: 272 SKLAQELEQXXXXXXXXXXXXXXLAKQ-SIEPSCEEKTEIEEKGSLEIANMTELTKKIEL 330 S QE+++ + +Q +++ KT I+EK + T K + Sbjct: 2143 SFDDQEIQRLNGLISQKLSENEQMRQQFNLQADAMNKT-IQEKDEMINQIKTRANKLLNE 2201 Query: 331 LEHLNCQIRQTNKELENKLATMGTESKAVSSPS----KKGSPLISRKSGRNTA--SKMKS 384 + N ++ KE E KL+ E + S + IS A +KMK Sbjct: 2202 KLNENSNLQNLQKENEEKLSQKENELNQIKSQLNTVIQNAQSQISALQNEKIAIENKMKQ 2261 Query: 385 PWSQLSSETL-NQDTDKKIN--KNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXX 441 + + L N+ +++ ++ + E +KLE + +L K +E + K Sbjct: 2262 QEDLIQNMKLANESSEQSLSLLEGENSKLEQICANLKKS--KEEEIEKMKAMFNEYKVKV 2319 Query: 442 XXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDL 501 + +++Q + Q ++ + + ++ +++EI +Q ++ N+ + N+K Sbjct: 2320 MQDRTEILSQNEQLKQNYISLQN--ELASSRNNLSEINSLQSKVNDLQNE---NSNIKSK 2374 Query: 502 IEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNF-SKVSDSNKEIVRL 560 + S+ +Q ++N E+ N N+ N++ +L ++Q + ++ +K+++ KE Sbjct: 2375 ANSMLSSMQQ--KIN-ELQTENINL----KNNQSQLNELQNSNNSLQTKLNELEKENETK 2427 Query: 561 TEELHHLSQKVAELEEEKGNLQLH---LVDYDSGRMIESDVYKKMIEMENLA----ETRL 613 E+ L QK+ EL+ + ++ +++ + ++ ES ++ EN + ET++ Sbjct: 2428 NSEISSLQQKLNELQNDNTTIKNKANSILNSLNNQLKESQTKLNELQNENTSIKTLETQI 2487 Query: 614 KAISLL-ESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALS 672 ++ E+ K + ++ L + E+++++ +ISQLQS+ + ++ L E+I L+ Sbjct: 2488 HSLQTENETIKSQSQETINSLNSRISELQNQIQEISQLQSELNDLKTENQSLHEKISELT 2547 Query: 673 AS--KKELALVIENLKL--DKEQL-YGTIKDLEND----------KEDIMNKLQNYIQEN 717 S K L IEN ++ KEQ+ + +L+N+ KE+ KL N E Sbjct: 2548 NSYNSKISELQIENQEILSSKEQISQSKLSELQNENQSLKLQISEKEEENEKLMNSNSEL 2607 Query: 718 MDLTDKLEKMSAEKISELLAKINHEEQSKIQ-TQFGIDAKIQERDLYIENIESELSKYKS 776 M+ D +++ + ++IS L A IN E+Q+KI I +ER +E+++S + + KS Sbjct: 2608 MNQIDLVKEDTKKEISHLQATIN-EKQTKIDGLNSQISQNEEERIGKLESLQSTIDEDKS 2666 Query: 777 RICRLEESIAVME------DRRYS-LERKADQLGSYLQEKQKAYSEYTIQ---------- 819 +I LE+ ++ +E + YS +E K Q +++ + + A++E + Sbjct: 2667 QIEILEQKVSDLESKLENLQKHYSEIETKNSQYENFISKARVAFNENKAKISQLETENNS 2726 Query: 820 -EDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNA 878 ++++VN + +D ++ + +++ EN +L+++ L++ENQ + + +Q N Sbjct: 2727 LKEKVVNYENAISSNDSQLKNFISQMKEENSKLEEEKSQLIKENQRIPQLEEENKQFANQ 2786 Query: 879 LV---EKANRTDL-AESESTKYQTQLRDLESNLKRITHEHQTL---IVQKKKEIEDLEIE 931 L EK + D E E TK T+ +LE +K++ +++ + VQ +++ + + + Sbjct: 2787 LSKFNEKLTQIDRETEEEKTKLLTEKSNLEEEIKQLKQQNEEINNEKVQLEEQFSNAKSK 2846 Query: 932 FNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDK 991 +I + + +N E ++L Q+ E+ N +L + +++ +L ++ Sbjct: 2847 LAEEINQIKKPNEEINNDQSNKEEEKSKLREQINEFLNERTHLQEQIHQISNEKSQLQEE 2906 Query: 992 --HVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESK 1049 V+KQ + + + N+ ++L +E + + Q+ N Q S M S+YE + Sbjct: 2907 LNEVKKQNEKINEEIQLLNNDKSQLQEDKSALEEVLKQMEQQ--NDQSSTEEMKSNYEKQ 2964 Query: 1050 LAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKT 1109 + +K+ +E ++ +S+ + K L+ ++ + ++ K ++E KL FE + Sbjct: 2965 INDLQSKVSELENKL--ISQ--TEEKSQIANLESVIEKLRNENKNIEEEKLKFEKQVKDL 3020 Query: 1110 EGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQ 1169 + + T + D + + + +Q + +++ ++++ + Q Sbjct: 3021 Q--TNAETNDQREDKITELKLRNAELQQQMKDYQNNSQINLLQNQ--IKDLQSQISAQKQ 3076 Query: 1170 ECYTKIIQLETLNTEL-TGHDVVNQE-QINQ-LKSKLEQLNTENDNLLSTVAELRSSISS 1226 + Y + I +T N E G +VVN++ +++ K ++L EN+ L +++L + ++S Sbjct: 3077 K-YEEQINSQTKNEEEDEGIEVVNRDINLDEGEKDDFQKLKEENEQLKKKISDLETKLNS 3135 Query: 1227 AVDQRGF---EIAEL 1238 V++ +IAEL Sbjct: 3136 YVNENAILQQKIAEL 3150 Score = 156 bits (379), Expect = 4e-36 Identities = 178/858 (20%), Positives = 370/858 (43%), Gaps = 56/858 (6%) Query: 764 IENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDEL 823 I + + + + R+ +LEE + + ++ +Q+ S ++ A S Q + Sbjct: 5 ISDKDKSIEEITERVNKLEEE---NKTKNSQIDEMKEQISSITTNEETAISTLNTQLNNK 61 Query: 824 VNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKA 883 N + +L H ++ K+ EI + + ++ + E + L+ + + ++ + + K Sbjct: 62 NNEIDLL--HQQLQSKET-EISKLTENVSEREKSFTELQEQLEKAKQEHEETISEIKLKL 118 Query: 884 NRTDLAESESTKYQTQLR-DLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRD 942 D +E +Q+R +LE K+ T +TL QK+ I ++ + E Sbjct: 119 ESKDNEINELNSTLSQIRSELEQTNKQNTELTETLS-QKESNINEINDNLSKLREEISEK 177 Query: 943 KKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPD 1002 +K +NEK K E Q+ + K E +N N+EE NK I++ +QQ +S Sbjct: 178 EKTINEKSSKIEELNQQISEKDNSLKEMTEKIN-NLEEENKQKNSRIEE--LQQQLESLR 234 Query: 1003 YTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEE 1062 ++ N IN L L QK+ +I LN+ + Q +++S ++ + +K+ +EE Sbjct: 235 NDDE--NRINNLYEELSQKESKINELNELMMQQQTGKETILSQLNEQIKEKDSKIGELEE 292 Query: 1063 EMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMI--ISSTIEP 1120 + ++ ++ + + EL V E+D + ++ E K + + MI ++ I+ Sbjct: 293 NVSKLESEISQKESNINELSSQVSEKDKMVNDISEEKNELQKQLSDQNSMIDELNEQIKE 352 Query: 1121 MSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLET 1180 ++D+ + L ++E E S L+E+ +KL TE K+IQ Sbjct: 353 LTDNLSKSTTESTEKDSKNQELISEKETEI----SHLKEEISKL-TEQHGEKDKLIQ--E 405 Query: 1181 LNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWK 1240 L ++ D +N +Q + S+L+ L ++ + LS + ++++ +I EL Sbjct: 406 LTEQIQTQD-INLKQKDSNISELQVLVSQKETELSEKDNSINEFIHKLEEKDLQIKEL-N 463 Query: 1241 QHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQ 1300 + L +E+ +EL Q+S E+ +++ D V + + NK ++ +L Sbjct: 464 EQLNNKESQI----NELNAQISDKENSLQEITDKVHTLEETVQNK---ETEINQKNEELS 516 Query: 1301 DKEEHLRNLQEKYADVINQIEILRSEI--EDEKVAFXXXXXXXXXXXXXXXXDLRTENQS 1358 ++E + L E + ++I+ EI + K+ D ++ Sbjct: 517 ERETKINELNEIISQKDSEIQQKNEEISSNNSKIDELNQQISNKENSLQELTDKVHSLET 576 Query: 1359 YKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQ 1418 QE I + + ++ ++ + + D ++KV E+ ++ KD I Sbjct: 577 KNSEQETQIDELTKLVSEKEEENNKLQETIQTKETEIKDKQSKVDEMNQEISDKDKSI-- 634 Query: 1419 KTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENAN-----HY 1473 E T + + +E + Q+ E +++I +T +E+ ++ L +++ N H Sbjct: 635 --EEITERVNKLEEENKTKNSQIDEMKEQISSITTNEETAISTLNTQLNNKNNEIDLLHQ 692 Query: 1474 ETMQKESEIERV---------KLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQT 1524 + KE+E E+ KL EE+ K T LN+Q++ N+ + + K + T Sbjct: 693 QLQSKETENEKAINELNDKLNKLYEEIANKNTNITELNEQISSKNQEIVDRDNKLQSLGT 752 Query: 1525 ALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDN---TMNKELL 1581 L + EI + +I ++V S+I + +D + E+L+N T + +L Sbjct: 753 ELNQKNEEIKEKDSKIGEFNDLVSKKDSEINQLQEEIADI-SSKIEELNNEIATKDASIL 811 Query: 1582 DAVPR-AELDLAMYMLHQ 1598 + + AE DL + L + Sbjct: 812 ELNNKIAEKDLKIKSLDE 829 Score = 114 bits (274), Expect = 2e-23 Identities = 194/976 (19%), Positives = 415/976 (42%), Gaps = 73/976 (7%) Query: 140 QLGDVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINE-KDQIIEAKNKATTXXXX 198 QL ++ + +N+++ K L+ L+ + + + I LQ+K+NE ++ KNKA + Sbjct: 2402 QLNELQNSNNSLQTK---LNELEKENETKNSEISSLQQKLNELQNDNTTIKNKANSILNS 2458 Query: 199 XXXXXXXXXXXXXE--DTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEA 256 E + + ++ +++ E + K + + I S + RIS L+ Sbjct: 2459 LNNQLKESQTKLNELQNENTSIKTLETQIHSLQTENETIKSQSQETINSLNSRISELQ-- 2516 Query: 257 NKLLEAARFEISLEHSKLA-QELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGS 315 N++ E ++ + L K Q L + + + K +I + Sbjct: 2517 NQIQEISQLQSELNDLKTENQSLHEKISELTNSYNSKISELQIENQEILSSKEQISQSKL 2576 Query: 316 LEIANMTELTK-KIELLEHLNCQIRQTNKELENKLATMGTESKA-VSSPSKKGSPLISRK 373 E+ N + K +I E N ++ +N EL N++ + ++K +S + ++ Sbjct: 2577 SELQNENQSLKLQISEKEEENEKLMNSNSELMNQIDLVKEDTKKEISHLQATINEKQTKI 2636 Query: 374 SGRNT--ASKMKSPWSQLSSETLNQDTDK---KINKNEIAKLEMVIQSLNKDLVDKEYVI 428 G N+ + + +L S D DK +I + +++ LE +++L K + E Sbjct: 2637 DGLNSQISQNEEERIGKLESLQSTIDEDKSQIEILEQKVSDLESKLENLQKHYSEIETKN 2696 Query: 429 SEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQE 488 S+ + I+QL+ E+ SL N E N I+ QLK Sbjct: 2697 SQYENFISKARVAFNENKAKISQLETENN------SLKEKVVNYE--NAISSNDSQLKNF 2748 Query: 489 LNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDN-- 546 ++ ++K+ N K +E+ KS + Q +++ NK S KL Q+ + + Sbjct: 2749 IS-QMKEENSK--LEEEKSQLIKENQRIPQLEEENKQFANQLSKFNEKLTQIDRETEEEK 2805 Query: 547 ---FSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVD-YDSGRMIESDVYKKM 602 ++ S+ +EI +L ++ ++ + +LEE+ N + L + + + ++ Sbjct: 2806 TKLLTEKSNLEEEIKQLKQQNEEINNEKVQLEEQFSNAKSKLAEEINQIKKPNEEINNDQ 2865 Query: 603 IEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSV 662 E + I+ +++ L +++H + + +++++L ++ + Q++++ EI+ + Sbjct: 2866 SNKEEEKSKLREQINEFLNERTHLQEQIHQISNEKSQLQEELNEVKK-QNEKINEEIQLL 2924 Query: 663 HLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQE--NMDL 720 + ++ L K L V++ ++ +Q + ++++++ E +N LQ+ + E N + Sbjct: 2925 NNDKS--QLQEDKSALEEVLKQMEQQNDQ--SSTEEMKSNYEKQINDLQSKVSELENKLI 2980 Query: 721 TDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICR 780 + EK + ++ K+ +E ++ + + + ++++ E + K R Sbjct: 2981 SQTEEKSQIANLESVIEKLRNENKNIEEEKLKFEKQVKDLQTNAETNDQREDKITELKLR 3040 Query: 781 LEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQ 840 E M+D Y + + L + +++ Q S + +E +N + D +E Sbjct: 3041 NAELQQQMKD--YQNNSQINLLQNQIKDLQSQISAQKQKYEEQINSQTKNEEEDEGIEVV 3098 Query: 841 LLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKAN--RTDLAE-----SES 893 +I + E + Q L EEN+ L+ +SD++ N+ V + + +AE S Sbjct: 3099 NRDINLDEGE-KDDFQKLKEENEQLKKKISDLETKLNSYVNENAILQQKIAELGGDIDVS 3157 Query: 894 TKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKN 953 Y + + + L+ + L ++ K IEDLE +I+S V N YE Sbjct: 3158 IDYGSDKDAIIAKLRILLQRALRLDKKRVKTIEDLE----EKIKSF--GVSVHNSSYE-- 3209 Query: 954 IEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINK 1013 QLE Q++E K IEN N ++L + N E + K VQK T E+ I Sbjct: 3210 ----AQLEEQIKELKQKIEN-NEASDDLIQKN-ESLKKMVQKSNTLYGQLMEENQQLIKT 3263 Query: 1014 LNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLD 1073 L + + D + +K Q + +VS E+++ + T + + V +D Sbjct: 3264 LKSYKAKSDSG--SSPKKPTRVQ---LKIVSTNETEIEEIVTPSQTNRNDQSNV----MD 3314 Query: 1074 SKQHNEELQILVREQD 1089 LQ ++++D Sbjct: 3315 RYLRRSLLQFFLQDED 3330 >UniRef50_A2DGN0 Cluster: Viral A-type inclusion protein, putative; n=1; Trichomonas vaginalis G3|Rep: Viral A-type inclusion protein, putative - Trichomonas vaginalis G3 Length = 4263 Score = 232 bits (567), Expect = 7e-59 Identities = 316/1559 (20%), Positives = 667/1559 (42%), Gaps = 112/1559 (7%) Query: 92 ESLANTLKQKEILMEKIKQYKELSKRSSTTI--VRXXXXXXXXXXXXXXXQLGDVTHLSN 149 ES K+ L +I+ Y++ T+ +R + D+ Sbjct: 1259 ESTEALQKKSRELYRQIRDYEQRLSSLGLTVEQIREMEMTIKNQANIIKAKDDDLKQTKE 1318 Query: 150 TIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXX 209 ++ ++ + + + I L+++I+E + ++E K+K Sbjct: 1319 ILEYREEQIEKFIAESVSIRDAIETLKQRISELEMLLEKKDKENNDKIAEIQEENRQTL- 1377 Query: 210 XXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISL 269 E +Q+ + +E+ +E + +Q +I KD +I + K LE E+ Sbjct: 1378 --EQLAKQLQEAEEDINVLEGNCQVYEQ----EIAEKDKQIEQMTNDIKSLE----EVIN 1427 Query: 270 EHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIE 329 E S L+Q ++ E + +T+IE+K + N E+ + + Sbjct: 1428 EQSNTIDSLKQDVATKEEEIKQLKQTVSENEEVIKQLQTDIEQKDAEIQKNKEEIEQHKQ 1487 Query: 330 LLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQL 389 + + I+Q E+E T+ ++ + IS + T ++++ Q Sbjct: 1488 TISQRDETIKQLQSEIEQHKQTIADKNNEIEQLKNT----ISERE--ETIKQLQNEIEQH 1541 Query: 390 SSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLI 449 +D + + NK EI + + I + N ++ + ISE+D +D I Sbjct: 1542 KQTMAERDAEIQKNKEEIEQQKQTISNNNNEIEQLKKTISERDAEIEQLKKTIAERDESI 1601 Query: 450 AQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAE 509 QLQ E +QH + + ++ ++ + +Q Q + + K+ +K L +++ + Sbjct: 1602 KQLQNEIEQHKQ-----TISQRDAEIEQLKQTVQQRDQTIAE--KEDLIKQLQSEIEQHK 1654 Query: 510 EQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSK-VSDSNKEIVRLTEELHHLS 568 + I+ N+EI+ K + + +KQ+Q I+ + +++ + EI + EE+ Sbjct: 1655 QTISDKNNEIEQL-KQTVNARDE---AIKQLQSEIEQHKQTIAERDAEIQKNKEEIEQQK 1710 Query: 569 QKVAELEEEKGNLQLHLVDYD---SGRMIESDVYKKMIEM--ENLAETR--LKAI-SLLE 620 Q +++ +E LQ + + S R E + K+ ++ + +AE +K + S +E Sbjct: 1711 QTISQRDETIKQLQNEIEQHKQTISQRDAEIEQLKQTVQQSDQTIAEKEDLIKQLQSEIE 1770 Query: 621 SQKFDLVQELHILQQKYDEVEDKLADISQLQSD--QVCSEIKS-----VHLEEQIDALSA 673 K + + +Q+ +E+E + ISQ Q+ SEI+ E++I+ Sbjct: 1771 QHKQTIAERDAEIQKNKEEIEQQKQTISQRDESIKQMQSEIEQNKQTIADREKEIEQHKQ 1830 Query: 674 SKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKIS 733 + E I+ L+ + EQ TI E D E NK + IQ+ + + L EK Sbjct: 1831 TIAERDNSIKQLQEEIEQHKQTI--AERDAEIQKNKEE--IQQKNEAINALTNEGEEKRL 1886 Query: 734 ELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRY 793 ++L ++ ++ I ++ + + +L EN S + + I L + I +E + Sbjct: 1887 KIL-ELEANNENLINKVKELNDSVSDLNLSTENQNSVVKQMTDEIKDLNKQIHELEVKSE 1945 Query: 794 SLERKADQLGSYLQE--KQKAYSEYTIQE-DELVNRLAVLMDHDRVVEKQLLEIEHENKE 850 + +++ ++ +Q KA +E I++ E V L + + K L E E Sbjct: 1946 NQQKQIEEKDKEIQSLTNTKAQNEELIKKLQEEVENLTNTKNQNEETIKNLQEQVQSLTE 2005 Query: 851 LQKKNQILLEENQNLQISLSDMQQHYNALVEKANR--TDLAESESTKYQTQLRDLESNLK 908 + +N+ L+++ Q SL++ + ++ L E+++T +T ++ L+ ++ Sbjct: 2006 TKNQNEDLIKKQQEQIQSLTNTKNENEETIKNLQEQVQSLTETKATNEET-IKKLQGEVQ 2064 Query: 909 RITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYK 968 +T T Q KK+ E+++ NT+ E+ KK L E+ + TQ E Q+++ + Sbjct: 2065 SLTETKATNEEQIKKQQEEIQSLSNTKNENEELIKK-LQEEIQNLTNTKTQNEEQIKKLQ 2123 Query: 969 NNIENL-NMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQ---KDEE 1024 I+NL N E+ +K+N + + + S + T ++IN N++N L KQ KD Sbjct: 2124 EEIQNLQKQNAEKDDKIN--EFNAKLSTLSSSSDELTTKFINAQNEINQLTKQNNEKDNL 2181 Query: 1025 IIALNQKINNAQVSYMSMVSDYESKLAQFTTKLE-----------NMEEEMQRVSKQLLD 1073 I LNQKI++ + + S + + +S+L Q T LE N+EEE Q++ + + Sbjct: 2182 ISQLNQKISDLE-NAKSQLENEKSQLIQEKTNLEQEKAQLLEQKKNLEEEKQKLETEKTN 2240 Query: 1074 SKQHNEELQILVREQDDQIKELKETKLTFEMNIPK--TEGMIISSTIEPMSDDANNVDXX 1131 +Q +L + + +L E K E K E + + ++ N++ Sbjct: 2241 LEQEKAKLIEEKTNLEQEKAKLIEEKTNLEQEKAKLIEEKTNLEQEKAKLIEEKTNLEQE 2300 Query: 1132 XXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKL---NTELQECYTKIIQLETLNTELTGH 1188 L+ QE+ + I+E++ L+++ AKL T L++ K+I+ +T + Sbjct: 2301 KAKLIEEKTNLE-QEKAKPIEEKTNLEQEKAKLIEEKTNLEQEKAKLIEEKTNLEQEKAK 2359 Query: 1189 DVVNQEQINQLKSKL--EQLNTEND--NLLSTVAELRSSISSAVDQRGFEIAELWKQHLA 1244 + + + Q K+KL E+ N E + L+ L + ++++ E K L Sbjct: 2360 LIEEKTNLEQEKAKLIEEKTNLEQEKAKLIEEKTNLEQEKAKLIEEK--TNLEQEKAKLI 2417 Query: 1245 QREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEE 1304 + + + ++ + +L + + E + QLLD + + +EE ++ T E+ +++K ++E Sbjct: 2418 EEKTNLEQEKAKLIEEKTNLEQEKSQLLDQ-KKNLEEEKQRLET-EKAKLIEDKTNLEQE 2475 Query: 1305 HLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQE 1364 + L++K +E ++++E+EK + + + + E Sbjct: 2476 KAQLLEQK-----KNLEEEKAKLEEEKAQAQKTIEEKDQEIEDLTSQINVKTKDL-SLLE 2529 Query: 1365 QSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYT 1424 N++ NA +ND + ++ ++T + E+ K+ + Sbjct: 2530 SDFNNMSFTNADQSTMISNYEKELSDKNKEINDLQNQLKQMTQNRD----ELQSKSDKLN 2585 Query: 1425 ITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIER 1484 + ++ + +N+ L + K EDL + L ++ + E + KE + Sbjct: 2586 EEIEEKKN-IQNLESSLEQKNKENEDLKQQLNKTQGELSAQLQQKTQELENLTKEFNDLK 2644 Query: 1485 VKLIEELNVKITESVSLNKQVAELNKALEEEVA-KTNEMQTALENQEIEIVTLNDEITNL 1543 K + + E +L K VAE +K + + + + NE++ L ++E E +L + I+ Sbjct: 2645 QKSEQTIAQNNEEIANLKKNVAERDKKISQLLENEVNELKKKLSDKENENTSLKNTISER 2704 Query: 1544 QNMVRASSSKIQKHVSFASDTKQGRDEQLDN--TMNKELLDAVPRAELDLAMYMLHQRD 1600 +N + + ++K+VS K+ QL N TM + L+ + E+ A ++ Q+D Sbjct: 2705 ENEI----NNLKKNVS----DKENEINQLKNNLTMRETELNKMKDEEVKNAKQIIAQKD 2755 Score = 223 bits (544), Expect = 4e-56 Identities = 300/1539 (19%), Positives = 651/1539 (42%), Gaps = 108/1539 (7%) Query: 106 EKIKQYKE-LSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNALSVLQVK 164 E+I+Q K+ +S+R T ++ + ++ L T+++ D ++ + Sbjct: 1704 EEIEQQKQTISQRDET--IKQLQNEIEQHKQTISQRDAEIEQLKQTVQQSDQTIAEKEDL 1761 Query: 165 MKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQEN 224 +K +++ I ++ I E+D I+ KNK E KQ +++++N Sbjct: 1762 IKQLQSEIEQHKQTIAERDAEIQ-KNKEEIEQQKQTISQRD------ESIKQMQSEIEQN 1814 Query: 225 FIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXX 284 + A+ + E ++ + I +D I L+E + + E E K +E++Q Sbjct: 1815 KQTI-ADREKEIEQHKQTIAERDNSIKQLQEEIEQHKQTIAERDAEIQKNKEEIQQKNEA 1873 Query: 285 XXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLE--IANMTELTK-KIELLEHLNCQIRQT 341 + +E + I + L ++++ T+ + +++ + +I+ Sbjct: 1874 INALTNEGEEKRLKILELEANNENLINKVKELNDSVSDLNLSTENQNSVVKQMTDEIKDL 1933 Query: 342 NKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKK 401 NK++ + K + K+ L + K+ K +L E N K Sbjct: 1934 NKQIHELEVKSENQQKQIEEKDKEIQSLTNTKAQNEELIK------KLQEEVENLTNTKN 1987 Query: 402 INKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHME 461 N+ I L+ +QSL + E +I ++ + I LQ + Q E Sbjct: 1988 QNEETIKNLQEQVQSLTETKNQNEDLIKKQQEQIQSLTNTKNENEETIKNLQEQVQSLTE 2047 Query: 462 GPSLIHVGTNTEDVNEI-AKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEID 520 + TN E + ++ +VQ + + +E + ++ I+ L + + + +L ++ Sbjct: 2048 TKA-----TNEETIKKLQGEVQSLTETKATNEEQIKKQQEEIQSLSNTKNENEELIKKLQ 2102 Query: 521 AANKNMIKVKSNHKLKLKQMQKTIDNFSKVS-DSNKEIVRLTEELHHLSQKVAELEEEKG 579 +N+ K+ ++ ++K++Q+ I N K + + + +I +L LS EL + Sbjct: 2103 EEIQNLTNTKTQNEEQIKKLQEEIQNLQKQNAEKDDKINEFNAKLSTLSSSSDELTTKFI 2162 Query: 580 NLQ-----LHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQE-LHIL 633 N Q L + + +I S + +K+ ++EN S L +K +L QE +L Sbjct: 2163 NAQNEINQLTKQNNEKDNLI-SQLNQKISDLENAKSQLENEKSQLIQEKTNLEQEKAQLL 2221 Query: 634 QQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLY 693 +QK + E+K +L++++ E + L E+ L K +L NL+ +K +L Sbjct: 2222 EQKKNLEEEK----QKLETEKTNLEQEKAKLIEEKTNLEQEKAKLIEEKTNLEQEKAKLI 2277 Query: 694 GTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGI 753 +LE +K ++ + N QE L ++ + EK + K N E++ + Sbjct: 2278 EEKTNLEQEKAKLIEEKTNLEQEKAKLIEEKTNLEQEKAKPIEEKTNLEQEKAKLIEEKT 2337 Query: 754 DAKIQERDLYIE--NIESELSKYKSRICRLEESIAVMEDRRYSLERKADQL----GSYLQ 807 + + ++ L E N+E E +K LE+ A + + + +LE++ +L + Q Sbjct: 2338 NLEQEKAKLIEEKTNLEQEKAKLIEEKTNLEQEKAKLIEEKTNLEQEKAKLIEEKTNLEQ 2397 Query: 808 EKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQI 867 EK K E T E E A L++ +E++ ++ E L+++ LL++ +NL+ Sbjct: 2398 EKAKLIEEKTNLEQEK----AKLIEEKTNLEQEKAKLIEEKTNLEQEKSQLLDQKKNLEE 2453 Query: 868 SLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIED 927 ++ L+E + +++ + + L + ++ L+ + Q I +K +EIED Sbjct: 2454 EKQRLETEKAKLIEDKTNLEQEKAQLLEQKKNLEEEKAKLEEEKAQAQKTIEEKDQEIED 2513 Query: 928 LEIEFNTQ------IESAIR-------DKKVLNEKYEKNI----EYVTQLEAQLQEYKNN 970 L + N + +ES D+ + YEK + + + L+ QL++ N Sbjct: 2514 LTSQINVKTKDLSLLESDFNNMSFTNADQSTMISNYEKELSDKNKEINDLQNQLKQMTQN 2573 Query: 971 IENLNMNVEELN-----KMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEI 1025 + L ++LN K N++ ++ ++++ ++ D +Q +L+A L+QK +E+ Sbjct: 2574 RDELQSKSDKLNEEIEEKKNIQNLESSLEQKNKENEDLKQQLNKTQGELSAQLQQKTQEL 2633 Query: 1026 IALNQKINN-AQVSYMSM------VSDYESKLAQFTTKLEN-MEEEMQRVSKQLLDSKQH 1077 L ++ N+ Q S ++ +++ + +A+ K+ +E E+ + K+L D + Sbjct: 2634 ENLTKEFNDLKQKSEQTIAQNNEEIANLKKNVAERDKKISQLLENEVNELKKKLSDKENE 2693 Query: 1078 NEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXX 1137 N L+ + E++++I LK+ E I + + + + + N + Sbjct: 2694 NTSLKNTISERENEINNLKKNVSDKENEINQ-----LKNNLTMRETELNKMKDEEVKNAK 2748 Query: 1138 XXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQIN 1197 K ++ EE + + +K N EL++ +I L ++ + + + +I Sbjct: 2749 QIIAQKDKDLEELNGKFNDTNNNLSKANDELKQLKEQIESLNKQIEQMKCSNNLKESEIK 2808 Query: 1198 QLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHEL 1257 QL S L++ L + + S ++Q E+ EL +Q L Q + ++T+ +L Sbjct: 2809 QLTSNLQKYK----QALKELNDQNKQKDSQINQLNNEMKEL-QQTLKQTQEQLKETQDQL 2863 Query: 1258 RVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVI 1317 + +K ++ S + E K + + LQN L+ K+ L + ++K Sbjct: 2864 KQTQETLATKEKEFAKSAEDLNNELKKK---QQAIDDLQNNLKQKDAELTDTKQKLEAKT 2920 Query: 1318 NQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLR-TENQSYKQMQEQSILNINEENAQ 1376 N+ L+ + E+E + +L ++++S Q +E L +N A+ Sbjct: 2921 NEFNDLKQKAENEIASLRKEIEQLKAKLANTSKELEASKSESDLQKKENDKLKVN--LAK 2978 Query: 1377 LKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFEN 1436 + + + ND ++ E LE++ ++ T + + E Sbjct: 2979 IAEMYKTLKSESENNSAKSNDKIKQMQEKIQNLEIQVEKMKLANENLTNENKLQKETIEM 3038 Query: 1437 VRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESE--IERVKLIEELNVK 1494 + ++L+E K + E E+ L+ + +QK ++ + K E++ K Sbjct: 3039 LNKKLLESNKSLTASIKEYETLKRENNLQKDQITKLTSQVQKLTQDFTQLKKEKAEVDSK 3098 Query: 1495 ITESVSLNKQVAELNKALEEEVAKTNEMQTA----LENQEIEIVTLNDEITNLQNMVRAS 1550 + E + L Q + + L+ E K NE+ LE +E I + N+ +L N+ Sbjct: 3099 LNELLDLLAQKDKEIERLKSENQKLNELYQQITKDLEEKEFLIQSQNNRCIDLLNLTEKK 3158 Query: 1551 SSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAEL 1589 + +I +T Q ++ L+N++ K ++ ++ L Sbjct: 3159 NKEI--------ETLQISNDSLNNSLTKSQMELREKSTL 3189 Score = 199 bits (486), Expect = 4e-49 Identities = 310/1467 (21%), Positives = 621/1467 (42%), Gaps = 122/1467 (8%) Query: 151 IKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNK--ATTXXXXXXXXXXXXXX 208 + E +S + K+KIM I KI E + IE KNK +T Sbjct: 1216 LSEVPQQISYFENKVKIMNGMITQSNAKIKELESQIEKKNKQIESTEALQKKSRELYRQI 1275 Query: 209 XXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEIS 268 E + E ME K++ I++KD + +E + E + Sbjct: 1276 RDYEQRLSSLGLTVEQIREMEMTIKNQ----ANIIKAKDDDLKQTKEILEYREEQIEKFI 1331 Query: 269 LEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKI 328 E + +E K++ + E + E + + E + I Sbjct: 1332 AESVSIRDAIETLKQRISELEMLLEKKDKENNDKIAEIQEENRQTLEQLAKQLQEAEEDI 1391 Query: 329 ELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQ 388 +LE NCQ+ E ++A + + +++ K +I+ +S NT +K Sbjct: 1392 NVLEG-NCQV------YEQEIAEKDKQIEQMTNDIKSLEEVINEQS--NTIDSLK----- 1437 Query: 389 LSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTL 448 + ++ + K K +++ E VI+ L D+ K+ I + +D Sbjct: 1438 --QDVATKEEEIKQLKQTVSENEEVIKQLQTDIEQKDAEIQKNKEEIEQHKQTISQRDET 1495 Query: 449 IAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSA 508 I QLQ E +QH + T + NEI EQLK +++ ++ I++L++ Sbjct: 1496 IKQLQSEIEQHKQ--------TIADKNNEI----EQLKNTISER------EETIKQLQNE 1537 Query: 509 EEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTI-DNFSKVSDSNKEIVRLTEELHHL 567 EQ Q E DA +++ N K +++Q ++TI +N +++ K I E+ L Sbjct: 1538 IEQHKQTMAERDA------EIQKN-KEEIEQQKQTISNNNNEIEQLKKTISERDAEIEQL 1590 Query: 568 SQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLV 627 + +AE +E LQ + + + + ++ E+E L +T + + ++K DL+ Sbjct: 1591 KKTIAERDESIKQLQNEIEQH------KQTISQRDAEIEQLKQTVQQRDQTI-AEKEDLI 1643 Query: 628 QELHI-LQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLK 686 ++L ++Q + DK +I QL+ + L+ +I+ + E I+ K Sbjct: 1644 KQLQSEIEQHKQTISDKNNEIEQLKQTVNARDEAIKQLQSEIEQHKQTIAERDAEIQKNK 1703 Query: 687 LDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSK 746 + EQ TI + + + N+++ + Q ++E++ + + + I +E Sbjct: 1704 EEIEQQKQTISQRDETIKQLQNEIEQHKQTISQRDAEIEQLK-QTVQQSDQTIAEKEDLI 1762 Query: 747 IQTQFGID---AKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLG 803 Q Q I+ I ERD I+ + E+ + K I + +ESI M+ +E+ + Sbjct: 1763 KQLQSEIEQHKQTIAERDAEIQKNKEEIEQQKQTISQRDESIKQMQS---EIEQNKQTIA 1819 Query: 804 SYLQEKQKAYSEYTIQE-DELVNRL-AVLMDHDRVVEKQLLEIEHENKELQKKNQ---IL 858 +EK+ + TI E D + +L + H + + ++ EI+ +E+Q+KN+ L Sbjct: 1820 D--REKEIEQHKQTIAERDNSIKQLQEEIEQHKQTIAERDAEIQKNKEEIQQKNEAINAL 1877 Query: 859 LEENQNLQISLSDMQQHYNALVEKANRTDLAESE---STKYQT----QLRDLESNLKRIT 911 E + ++ + +++ + L+ K + + S+ ST+ Q Q+ D +L + Sbjct: 1878 TNEGEEKRLKILELEANNENLINKVKELNDSVSDLNLSTENQNSVVKQMTDEIKDLNKQI 1937 Query: 912 HEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNI 971 HE + ++K+IE+ + E + + ++++++ +K ++ +E +T + Q +E N+ Sbjct: 1938 HELEVKSENQQKQIEEKDKEIQSLTNTKAQNEELI-KKLQEEVENLTNTKNQNEETIKNL 1996 Query: 972 ENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQK 1031 + ++ E N +LI K Q++Q QS N N+ +K E++ +L + Sbjct: 1997 QEQVQSLTETKNQNEDLIKK--QQEQIQS------LTNTKNENEETIKNLQEQVQSLTET 2048 Query: 1032 INNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQ 1091 + + + + +S T E ++++ + + + L ++K NEE L+++ ++ Sbjct: 2049 KATNEETIKKLQGEVQSLTETKATNEEQIKKQQEEI-QSLSNTKNENEE---LIKKLQEE 2104 Query: 1092 IKELKETKLTFEMNIPKTEGMI--ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEE 1149 I+ L TK E I K + I + D N + L + Sbjct: 2105 IQNLTNTKTQNEEQIKKLQEEIQNLQKQNAEKDDKINEFNAKLSTLSSSSDELTTKFINA 2164 Query: 1150 FIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTE 1209 E + L +Q+ + + + + KI LE ++L ++ L+ + QL + Sbjct: 2165 -QNEINQLTKQNNEKDNLISQLNQKISDLENAKSQLENEKSQLIQEKTNLEQEKAQLLEQ 2223 Query: 1210 NDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADF--QKTEHEL-RVQLSAFES 1266 NL +L + ++ ++ I E K +L Q +A +KT E + +L ++ Sbjct: 2224 KKNLEEEKQKLETEKTNLEQEKAKLIEE--KTNLEQEKAKLIEEKTNLEQEKAKLIEEKT 2281 Query: 1267 KYEQ-LLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRS 1325 EQ ++ T E K +E+ T+L+ + E NL+++ A +I + ++ Sbjct: 2282 NLEQEKAKLIEEKTNLEQEKAKLIEEKTNLEQEKAKPIEEKTNLEQEKAKLIEE----KT 2337 Query: 1326 EIEDEKVAFXXXXXXXXXXXXXXXXD-LRTENQSYKQMQEQSILNINEENAQL---KKSS 1381 +E EK + E + K ++E++ N+ +E A+L K + Sbjct: 2338 NLEQEKAKLIEEKTNLEQEKAKLIEEKTNLEQEKAKLIEEKT--NLEQEKAKLIEEKTNL 2395 Query: 1382 XXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSE-IYQKTH---EYTITLTQRNDEFENV 1437 + +AK++E LE + ++ I +KT+ E + L Q+ + E Sbjct: 2396 EQEKAKLIEEKTNLEQEKAKLIEEKTNLEQEKAKLIEEKTNLEQEKSQLLDQKKNLEEEK 2455 Query: 1438 RQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITE 1497 ++ E K IED T E E A L L+ +N + +E + + K IEE + +I + Sbjct: 2456 QRLETEKAKLIEDKT-NLEQEKAQL-LEQKKNLEEEKAKLEEEKAQAQKTIEEKDQEIED 2513 Query: 1498 SVS-LNKQVAELNKALEEE---VAKTN-EMQTALENQEIEIVTLNDEITNLQNMVRASSS 1552 S +N + +L+ LE + ++ TN + T + N E E+ N EI +LQN ++ + Sbjct: 2514 LTSQINVKTKDLS-LLESDFNNMSFTNADQSTMISNYEKELSDKNKEINDLQNQLKQMTQ 2572 Query: 1553 KIQKHVSFASDTKQGRDEQLDNTMNKE 1579 + + SD E+ N N E Sbjct: 2573 N-RDELQSKSDKLNEEIEEKKNIQNLE 2598 Score = 174 bits (424), Expect = 1e-41 Identities = 279/1496 (18%), Positives = 616/1496 (41%), Gaps = 130/1496 (8%) Query: 142 GDVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXX 201 G N ++EK ++ ++ ++ M++ I + +I +Q + KNK Sbjct: 798 GSGNQFENLLQEKLTKIATMEKRINTMKSDIEKQKIEIATLNQDVSDKNKTIQQLQNKLK 857 Query: 202 XXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLE 261 + +++ E I E + K E L ++ KDV+I +++E K E Sbjct: 858 NKENSVQRLNGEITDLRSRISEYEILNERQAK-ENALLNNKLKQKDVQIENIKEQPKEEE 916 Query: 262 AARFEISLEHSKL-AQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIAN 320 ++ L +E +Q + + P E + + + N Sbjct: 917 EKPKQVGFAKPSLPPKESDQREFIKGSRSSGQLKFSPIATPPE-ENNNSLSQLEQFKKLN 975 Query: 321 MT------ELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKK--------G 366 T L K ++ L ++ +N +L+ + T E+K +++ K+ Sbjct: 976 TTIKEQSQRLLAKDRKIDLLKQRLNDSNNQLKEIMET--PENKRIAAKEKELEDFQQQLR 1033 Query: 367 SPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVI---QSLNKDLVD 423 S +IS+ S T Q+ E + + NEI +L ++ ++L +D + Sbjct: 1034 SQIISQSSSFITYENESDAMKQIKEENYRRVVENTHKDNEIIRLTKLLATDKTLKEDKIL 1093 Query: 424 KEYV------ISEKDTXXXXXXXXXXGKDTLIAQLQ-----LEHQ-QHMEGPSLIHVGTN 471 +E + + + K+ LQ L+ Q Q H Sbjct: 1094 QEKIMQLEAKVQQMKDFNKETAANLESKNLENYNLQDNINSLKEQIQKQNDEQANHQKEL 1153 Query: 472 TEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKS 531 E +IA +Q+++++ N ++ V EKL ++ ++ +LN+ + K+ I VK Sbjct: 1154 DERDEQIAVLQKEIEKYENRYLEQQEVISQ-EKLNNSNLKL-KLNEAENEIEKSHI-VKQ 1210 Query: 532 NHKLKLKQMQKTIDNFSK--------VSDSNKEIVRLTEELHHLSQKVAE---LEEEKGN 580 +L L ++ + I F ++ SN +I L ++ ++++ L+++ Sbjct: 1211 PGELYLSEVPQQISYFENKVKIMNGMITQSNAKIKELESQIEKKNKQIESTEALQKKSRE 1270 Query: 581 LQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEV 640 L + DY+ +++ EME + + ++++++ DL Q IL+ + +++ Sbjct: 1271 LYRQIRDYEQRLSSLGLTVEQIREMEMTIKNQ---ANIIKAKDDDLKQTKEILEYREEQI 1327 Query: 641 EDKLAD--------------ISQL---------QSDQVCSEIKSVH---LEEQIDALSAS 674 E +A+ IS+L +++ +EI+ + LE+ L + Sbjct: 1328 EKFIAESVSIRDAIETLKQRISELEMLLEKKDKENNDKIAEIQEENRQTLEQLAKQLQEA 1387 Query: 675 KKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSA---EK 731 ++++ ++ N ++ ++++ K +E DI L+ I E + D L++ A E+ Sbjct: 1388 EEDINVLEGNCQVYEQEIAEKDKQIEQMTNDI-KSLEEVINEQSNTIDSLKQDVATKEEE 1446 Query: 732 ISELLAKINHEEQSKIQTQFGI---DAKIQERDLYIENIESELSKYKSRICRLEESIAVM 788 I +L ++ E+ Q Q I DA+IQ+ IE + +S+ I +L+ I Sbjct: 1447 IKQLKQTVSENEEVIKQLQTDIEQKDAEIQKNKEEIEQHKQTISQRDETIKQLQSEIEQH 1506 Query: 789 EDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHEN 848 + + +QL + + E+++ + ++E+ + + D ++K EIE + Sbjct: 1507 KQTIADKNNEIEQLKNTISEREETIKQL---QNEIEQHKQTMAERDAEIQKNKEEIEQQK 1563 Query: 849 KELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQL--RDLE-S 905 + + N + + + + ++++Q + E+ ++E +++ + RD E Sbjct: 1564 QTISNNNNEIEQLKKTISERDAEIEQLKKTIAERDESIKQLQNEIEQHKQTISQRDAEIE 1623 Query: 906 NLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNI----EYVTQLE 961 LK+ + I +K+ I+ L+ E Q + I DK E+ ++ + E + QL+ Sbjct: 1624 QLKQTVQQRDQTIAEKEDLIKQLQSEIE-QHKQTISDKNNEIEQLKQTVNARDEAIKQLQ 1682 Query: 962 AQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYT-EQYINEINKLNALLKQ 1020 ++++++K I + +++ NK +E QKQ D T +Q NEI + + Q Sbjct: 1683 SEIEQHKQTIAERDAEIQK-NKEEIE-----QQKQTISQRDETIKQLQNEIEQHKQTISQ 1736 Query: 1021 KDEEIIALNQKINNAQVSYM---SMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQH 1077 +D EI L Q + + + ++ +S++ Q + + E+Q+ +++ KQ Sbjct: 1737 RDAEIEQLKQTVQQSDQTIAEKEDLIKQLQSEIEQHKQTIAERDAEIQKNKEEIEQQKQT 1796 Query: 1078 NEELQILVREQDDQIKELKETKLTFEMNIPKTEGMII--SSTIEPMSDDANNVDXXXXXX 1135 + +++ +I++ K+T E I + + I ++I+ + ++ Sbjct: 1797 ISQRDESIKQMQSEIEQNKQTIADREKEIEQHKQTIAERDNSIKQLQEEIEQ-----HKQ 1851 Query: 1136 XXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQ 1195 ++Q+ +E IQ+++ E L E +E KI++LE N L + Sbjct: 1852 TIAERDAEIQKNKEEIQQKN---EAINALTNEGEEKRLKILELEANNENLINKVKELNDS 1908 Query: 1196 INQLKSKLEQLNTENDNLLSTVAELRSSI-----SSAVDQRGFEIAELWKQHLAQREADF 1250 ++ L E N+ + + +L I S Q+ E + Q L +A Sbjct: 1909 VSDLNLSTENQNSVVKQMTDEIKDLNKQIHELEVKSENQQKQIEEKDKEIQSLTNTKAQN 1968 Query: 1251 QKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQ 1310 ++ +L+ ++ + Q +++++ ++ + T Q L K Q++ + L N + Sbjct: 1969 EELIKKLQEEVENLTNTKNQNEETIKNLQEQVQSLTETKNQNEDLIKKQQEQIQSLTNTK 2028 Query: 1311 EKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQE--QSIL 1368 + + I ++ + + K T + K+ QE QS+ Sbjct: 2029 NENEETIKNLQEQVQSLTETKATNEETIKKLQGEVQSLTETKATNEEQIKKQQEEIQSLS 2088 Query: 1369 NINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLT 1428 N EN +L K + + K+ E L+ +++E K +E+ L+ Sbjct: 2089 NTKNENEELIKKLQEEIQNLTNTKTQNEEQIKKLQEEIQNLQKQNAEKDDKINEFNAKLS 2148 Query: 1429 QRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLI 1488 + + + + + + I LT ++ +E L ++++ + E + + E E+ +LI Sbjct: 2149 TLSSSSDELTTKFINAQNEINQLT-KQNNEKDNLISQLNQKISDLENAKSQLENEKSQLI 2207 Query: 1489 EELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQ 1544 +E T Q+ E K LEEE K +T LE ++ +++ +E TNL+ Sbjct: 2208 QEK----TNLEQEKAQLLEQKKNLEEEKQKLETEKTNLEQEKAKLI---EEKTNLE 2256 Score = 171 bits (415), Expect = 2e-40 Identities = 306/1526 (20%), Positives = 632/1526 (41%), Gaps = 133/1526 (8%) Query: 152 KEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKN-KATTXXXXXXXXXXXXXXXX 210 +EKD A+S LQ +++ T I +EKI++ + IEAK+ K Sbjct: 500 EEKDKAISKLQKQIERQNTIIQQNEEKIDQLSKDIEAKDQKIDEMIQKSLTAEVPSGDGA 559 Query: 211 XEDTKQQMTKMQENFIAMEAE---WKDEKQRLLKDIESK-DVRISSLEEA---------N 257 + K Q ++IA++ E KD K L+D K D +IS L Sbjct: 560 ALELKLQNL---NSYIAIQNEKMGQKDAKIEQLEDERQKNDTKISELTSTLTQLKLTNNE 616 Query: 258 KLLEAARFEISLEHSKLAQ--------ELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTE 309 L+ A E ++ S + + E+ Q + K E + E Sbjct: 617 NTLKIAELENTIAKSNIPKKEGELYLSEVPQEVSFLKNKNNMLNNINKSQAEKIKHLEQE 676 Query: 310 IEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPL 369 I +K +I ++ E+ KK L+ QI+ +L + G E+ A K+ S L Sbjct: 677 IVKKNK-QIGSIDEMHKKSRELQR---QIQDYENKLNAQQLESGGENSAELLSLKQQSNL 732 Query: 370 ISRKSG--RNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYV 427 +++ + ++K + + +D + K+ ++++ + S NK + D E Sbjct: 733 LNQLVADLKKQNIELKKTLETKDKQLSSMMSDSLLVKDNLSEITAELASKNKIIHDYELR 792 Query: 428 ISEKDTXXXXXXXXXXGKDTLIAQLQ--LEHQQHMEGPSLIHVGTNTEDVNE----IAKV 481 ++ K T IA ++ + + I + T +DV++ I ++ Sbjct: 793 LNALSGSGNQFENLLQEKLTKIATMEKRINTMKSDIEKQKIEIATLNQDVSDKNKTIQQL 852 Query: 482 QEQLK------QELNDEIKDVNVK----DLIEKLKSAEEQITQLNDEI---DAANKNMIK 528 Q +LK Q LN EI D+ + +++ + ++ E + LN+++ D +N+ + Sbjct: 853 QNKLKNKENSVQRLNGEITDLRSRISEYEILNERQAKENAL--LNNKLKQKDVQIENIKE 910 Query: 529 VKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLS-QKVAELEEEKGNLQLHLVD 587 + K KQ+ + +E ++ + L +A EE N L Sbjct: 911 QPKEEEEKPKQVGFAKPSLPPKESDQREFIKGSRSSGQLKFSPIATPPEENNNSLSQLEQ 970 Query: 588 YDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADI 647 + + ++++ + + + ++ +Q ++++ ++ E +L D Sbjct: 971 FKKLNTTIKEQSQRLLAKDRKIDLLKQRLNDSNNQLKEIMETPE--NKRIAAKEKELEDF 1028 Query: 648 SQLQSDQVCSEIKS-VHLEEQIDALSASKKE-LALVIENLKLDKE-----QLYGTIKDLE 700 Q Q+ S+ S + E + DA+ K+E V+EN D E +L T K L+ Sbjct: 1029 QQQLRSQIISQSSSFITYENESDAMKQIKEENYRRVVENTHKDNEIIRLTKLLATDKTLK 1088 Query: 701 NDK---EDIMN---KLQNYIQENMDLTDKLEKMSAE--KISELLAKINHEEQSKIQTQFG 752 DK E IM K+Q N + LE + E + + + + + Q + Q Sbjct: 1089 EDKILQEKIMQLEAKVQQMKDFNKETAANLESKNLENYNLQDNINSLKEQIQKQNDEQAN 1148 Query: 753 IDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQE---- 808 ++ ERD I ++ E+ KY++R +E I+ + +L+ K ++ + +++ Sbjct: 1149 HQKELDERDEQIAVLQKEIEKYENRYLEQQEVISQEKLNNSNLKLKLNEAENEIEKSHIV 1208 Query: 809 KQKA---YSEYTIQEDELVNRLAV---LMDHDRVVEKQL-LEIEHENKELQKKNQILLEE 861 KQ SE Q N++ + ++ K+L +IE +NK+++ + L ++ Sbjct: 1209 KQPGELYLSEVPQQISYFENKVKIMNGMITQSNAKIKELESQIEKKNKQIE-STEALQKK 1267 Query: 862 NQNLQISLSDMQQHYNAL---VEKANRTDLA-ESESTKYQTQLRDLESNLKRITHEHQTL 917 ++ L + D +Q ++L VE+ ++ ++++ + + DL+ + + + + + Sbjct: 1268 SRELYRQIRDYEQRLSSLGLTVEQIREMEMTIKNQANIIKAKDDDLKQTKEILEYREEQI 1327 Query: 918 ------IVQKKKEIEDLEIEFNTQIESAIRDK-KVLNEK----YEKNIEYVTQLEAQLQE 966 V + IE L+ +++E + K K N+K E+N + + QL QLQE Sbjct: 1328 EKFIAESVSIRDAIETLKQRI-SELEMLLEKKDKENNDKIAEIQEENRQTLEQLAKQLQE 1386 Query: 967 YKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQ----KD 1022 + +I L N ++ + + DK ++ Q T E+ INE + LKQ K+ Sbjct: 1387 AEEDINVLEGNC-QVYEQEIAEKDKQIE-QMTNDIKSLEEVINEQSNTIDSLKQDVATKE 1444 Query: 1023 EEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQ 1082 EEI L Q ++ + + +D E K A+ E +E+ Q +S++ KQ E++ Sbjct: 1445 EEIKQLKQTVSENEEVIKQLQTDIEQKDAEIQKNKEEIEQHKQTISQRDETIKQLQSEIE 1504 Query: 1083 ---ILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDA----NNVDXXXXXX 1135 + +++++I++LK T E I + + I DA N + Sbjct: 1505 QHKQTIADKNNEIEQLKNTISEREETIKQLQNEIEQHKQTMAERDAEIQKNKEEIEQQKQ 1564 Query: 1136 XXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKI-IQLETLNTELTGHDVVNQE 1194 ++++ ++ I ER EQ K E E ++ ++E ++ D E Sbjct: 1565 TISNNNNEIEQLKKTISERDAEIEQLKKTIAERDESIKQLQNEIEQHKQTISQRD-AEIE 1623 Query: 1195 QINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTE 1254 Q+ Q + +Q E ++L+ + + + EI +L KQ + R+ ++ + Sbjct: 1624 QLKQTVQQRDQTIAEKEDLIKQLQSEIEQHKQTISDKNNEIEQL-KQTVNARDEAIKQLQ 1682 Query: 1255 HELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYA 1314 E+ + ++ + + Q++ E + LQN++ E+H + + ++ A Sbjct: 1683 SEIEQHKQTIAERDAEIQKNKEEIEQQKQTISQRDETIKQLQNEI---EQHKQTISQRDA 1739 Query: 1315 DV--INQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINE 1372 ++ + Q + EK + E Q K+ EQ I++ Sbjct: 1740 EIEQLKQTVQQSDQTIAEKEDLIKQLQSEIEQHKQTIAERDAEIQKNKEEIEQQKQTISQ 1799 Query: 1373 ENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRND 1432 + +K+ R + E + + + ++ ++ ++ T+ +R+ Sbjct: 1800 RDESIKQMQSEIEQNKQTIADREKEIEQHKQTIAER-DNSIKQLQEEIEQHKQTIAERDA 1858 Query: 1433 EFENVRQQLVEYEKRIEDLTYE-KESELAILRLKMHENANHYETMQKESEIERVKLIEEL 1491 E + ++++ + + I LT E +E L IL L+ AN+ + K E+ + +L Sbjct: 1859 EIQKNKEEIQQKNEAINALTNEGEEKRLKILELE----ANNENLINKVKELN--DSVSDL 1912 Query: 1492 NVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASS 1551 N+ S+ KQ+ + K L +++ +E++ ENQ+ +I + EI +L N + Sbjct: 1913 NLSTENQNSVVKQMTDEIKDLNKQI---HELEVKSENQQKQIEEKDKEIQSLTNTKAQNE 1969 Query: 1552 ---SKIQKHVSFASDTKQGRDEQLDN 1574 K+Q+ V ++TK +E + N Sbjct: 1970 ELIKKLQEEVENLTNTKNQNEETIKN 1995 Score = 157 bits (381), Expect = 2e-36 Identities = 304/1497 (20%), Positives = 646/1497 (43%), Gaps = 156/1497 (10%) Query: 147 LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXX 206 L++ K+KD+ ++ L +MK ++ T+ QE++ E ++ + Sbjct: 2824 LNDQNKQKDSQINQLNNEMKELQQTLKQTQEQLKETQDQLKQTQETLATKEKEFAKSAED 2883 Query: 207 XXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEE-ANKLLEAARF 265 + +Q + +Q N +AE D KQ+L E+K + L++ A + + R Sbjct: 2884 LNNELKKKQQAIDDLQNNLKQKDAELTDTKQKL----EAKTNEFNDLKQKAENEIASLRK 2939 Query: 266 EISLEHSKLA---QELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMT 322 EI +KLA +ELE L K ++ E ++ + A Sbjct: 2940 EIEQLKAKLANTSKELEASKSESDLQKKENDKL-KVNLAKIAEMYKTLKSESENNSAKSN 2998 Query: 323 ELTKKI-ELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASK 381 + K++ E +++L Q+ + EN + + + +KK L+ +S ++ + Sbjct: 2999 DKIKQMQEKIQNLEIQVEKMKLANENLTNENKLQKETIEMLNKK---LL--ESNKSLTAS 3053 Query: 382 MKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXX 441 +K ETL ++ + + K++I KL +Q L +D + +E D+ Sbjct: 3054 IKE------YETLKRENN--LQKDQITKLTSQVQKLTQDFTQLKKEKAEVDSKLNELLDL 3105 Query: 442 XXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDL 501 KD I +L+ E+Q+ E I T+D+ E +E L Q N+ +++ +L Sbjct: 3106 LAQKDKEIERLKSENQKLNELYQQI-----TKDLEE----KEFLIQSQNNRC--IDLLNL 3154 Query: 502 IEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFS-KVSDSNKEIV-- 558 EK K+ E + Q+++ D+ N ++ K +++L++ ++N K+++SN+++ Sbjct: 3155 TEK-KNKEIETLQISN--DSLNNSLTK----SQMELREKSTLLENAKDKITESNRKLALF 3207 Query: 559 -RLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAIS 617 RL+ L+ + +K + D DS I + + +I +E + + Sbjct: 3208 DRLSANSSELNLTSSGRGIKKSSSMNLSTDMDSKNKIINQQEQTIIGLEQSLKVSKNEV- 3266 Query: 618 LLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQ-IDALSASK- 675 ++ K +L ++L ++ ++++ ++L++ ++ S +K ++ ++Q ID+L +S Sbjct: 3267 --DATKRELQKQLQNNKELQNQIKMTKEQFAKLEA-KLQSVVKKLNDKDQRIDSLMSSDP 3323 Query: 676 -----KELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDL--------TD 722 +L I +L L+ E+L + + + + + + L++ + L T+ Sbjct: 3324 NNKQTNQLNKQISDLNLENEKLKTRVDIITRENQSLKDDLESQKSQKSKLDESCNALKTE 3383 Query: 723 KLEKMSA-----EKISELLAKIN--HEEQSKIQTQFGIDAKIQERDLYIENIESE--LSK 773 + K S EK+ EL+ +IN +++ S+++ +F + ++R Y++ IE E +++ Sbjct: 3384 LINKKSIMDQYKEKLKELMEQINLKNKQISELKAEFN-GSDDEDRKSYVKVIEQEGEITE 3442 Query: 774 YKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQ-EDELVN-RLAVLM 831 K I R ++ + + + LE+ + Q+ K + ED N + M Sbjct: 3443 LKVIIDRQKKFVGQQKMKIADLEKNLKESNDEAQKMTKNLQTTIYELEDRCQNLNQTIEM 3502 Query: 832 DHDRVVEKQLLEIEHENKE---LQKKNQILLEE---------NQNLQISLSDMQQHYNAL 879 + R+ E + IE NKE L+ K IL E NL + +Q+ + Sbjct: 3503 KNFRLRENEKT-IEDLNKEIEFLKGKIDILSREISMYSDNSSKDNLISKIVSLQKTVSEK 3561 Query: 880 VEKANRTDLAESESTKYQTQLR-DLESNLKRITH-EHQTLIVQKK------KEIEDLEIE 931 E+ N + + S + + +++ +++ RI H E+Q ++ K KE ++I+ Sbjct: 3562 DEQLNDAKINSNNSLEIEDKMQQEIDQKNSRIHHLENQMRVLLNKASHENAKEESKVKID 3621 Query: 932 F---NTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENL-NMNVEELNKMNLE 987 N ++ + D L E+ V++LE ++E ++ I + N ++N+++ E Sbjct: 3622 LKKANVKLSNLENDFSSLQEENAALKSKVSKLELVIKEKQSEINIMAQKNNNDINEIS-E 3680 Query: 988 LIDKHVQKQQ---TQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVS 1044 L K ++KQ TQ E+ +EI++L LK K+ E+ +I + + Sbjct: 3681 LKSK-LRKQNEDFTQEKSSAEKQRSEIDQLTNDLKAKNNELDDSKSEIRILKSKINQLQQ 3739 Query: 1045 DYESK---LAQFTTKLENMEEEMQRVSKQLLDSKQHNEE-----LQILVREQDDQIKELK 1096 D+++K L + + KL +EE+M+ +LL+ N++ ++ L E +Q K+LK Sbjct: 3740 DFDAKNHSLQKESEKLSQLEEKMKEKELELLNKSLDNDKAAKEIIEKLQNENLEQSKQLK 3799 Query: 1097 ETKLTFE-----MNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFI 1151 + + E +N E + I + +D + L ++ EE + Sbjct: 3800 KKEKDIEQMKQILNDLNNEQGELKGKIMTLQNDNEQI----TKTSQEKFKLNEKKSEELV 3855 Query: 1152 QERSVLQEQSAKLNTELQ-ECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTEN 1210 + L ++ A+ N + K ++ L +L + N E+I L+S++ ++ N Sbjct: 3856 SMINKLNDEIAEKNKTINGTLLQKEKEITKLKNDLEQSQITN-ERITNLESEMMKMKQLN 3914 Query: 1211 DNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQ 1270 D+L++ + + ++ E+ EL ++ L Q + QK E + K + Sbjct: 3915 DDLMNDINRYNEELI----EKENELQEL-REKLIQSGNNLQKVTPEQ--SYFDLQMKITE 3967 Query: 1271 LLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADV-INQIEILRSEIED 1329 L D ++ + NK ++T+L +KL + + + + + + ++ I +E+E+ Sbjct: 3968 LEDIIKDKNSQLENKT---NEITNLYSKLYNTSPPSNSKKPRNTKLEVEKMRIKMAELEN 4024 Query: 1330 EKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXX 1389 + + K + IN+ N +L+K Sbjct: 4025 KNKDLIDQNTRMNSDLQAQINQNNKLKRHMKDNENNFNSQINQLNLKLQKVVSDYEARLL 4084 Query: 1390 XXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYT------------ITLTQR-NDEFEN 1436 N + +V EL +++ K+ EI K + I L+++ N++ N Sbjct: 4085 ILDNSKNQTQ-RVNELRERIKQKNEEILSKEKQINENKLENDKLKNEIELSKKQNEDLSN 4143 Query: 1437 VRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKIT 1496 Q K +E + + A + +++++ N E + K S IER L E+LN + Sbjct: 4144 YLSQKEAKIKELERRIQSLDEQNAKIEDELNKSINKNEEINKSSIIERTDLSEQLNNALK 4203 Query: 1497 ESVSLNKQVAELNKALEEEVAKTNEMQTA--LENQEIEI----VTLNDEITNLQNMV 1547 E+ L Q+ E ++E K +++ + +Q I++ L D+ L+NM+ Sbjct: 4204 ENSRLKVQIDETVSKIKELCDKDSDIARVKLVSDQLIDLSEYCKLLKDQNEELKNMI 4260 Score = 155 bits (375), Expect = 1e-35 Identities = 279/1583 (17%), Positives = 652/1583 (41%), Gaps = 127/1583 (8%) Query: 94 LANTLKQKEILMEKI-KQYKELSKRSSTTIVRXXXXXXXXXXXXXX-----XQL--GDVT 145 L+ L+QK +E + K++ +L ++S TI + QL +V Sbjct: 2622 LSAQLQQKTQELENLTKEFNDLKQKSEQTIAQNNEEIANLKKNVAERDKKISQLLENEVN 2681 Query: 146 HLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKD-QIIEAKNKATTXXXXXXXXXX 204 L + +K+N + L+ + E I +L++ +++K+ +I + KN T Sbjct: 2682 ELKKKLSDKENENTSLKNTISERENEINNLKKNVSDKENEINQLKNNLTMRETELNKMKD 2741 Query: 205 XXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAAR 264 ++ KQ + + ++ + ++ D L K + +E NK +E + Sbjct: 2742 EEV----KNAKQIIAQKDKDLEELNGKFNDTNNNLSKANDELKQLKEQIESLNKQIEQMK 2797 Query: 265 FEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTEL 324 +L+ S++ Q K+ + + ++ ++I + + E+ + + Sbjct: 2798 CSNNLKESEIKQ--------LTSNLQKYKQALKELNDQNKQKDSQINQLNN-EMKELQQT 2848 Query: 325 TKKI-ELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLIS--RKSGRNTASK 381 K+ E L+ Q++QT + L K ++ +++ KK I + + + ++ Sbjct: 2849 LKQTQEQLKETQDQLKQTQETLATKEKEFAKSAEDLNNELKKKQQAIDDLQNNLKQKDAE 2908 Query: 382 MKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXX 441 + +L ++T + K+ +NEIA L I+ L L + + K+ Sbjct: 2909 LTDTKQKLEAKTNEFNDLKQKAENEIASLRKEIEQLKAKLAN-----TSKELEASKSESD 2963 Query: 442 XXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDL 501 K+ ++ L M + +E N AK +++KQ + ++I+++ ++ Sbjct: 2964 LQKKENDKLKVNLAKIAEM------YKTLKSESENNSAKSNDKIKQ-MQEKIQNLEIQ-- 3014 Query: 502 IEKLKSAEEQITQLN----DEIDAANKNMIKVKSNHKLKLKQMQ--KTIDNFSK--VSDS 553 +EK+K A E +T N + I+ NK +++ + +K+ + K +N K ++ Sbjct: 3015 VEKMKLANENLTNENKLQKETIEMLNKKLLESNKSLTASIKEYETLKRENNLQKDQITKL 3074 Query: 554 NKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSG-RMIESDVYKKMIEMENLAETR 612 ++ +LT++ L ++ AE++ + L L D ++S+ K + + + Sbjct: 3075 TSQVQKLTQDFTQLKKEKAEVDSKLNELLDLLAQKDKEIERLKSENQKLNELYQQITKDL 3134 Query: 613 LKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEI----KSVHLEEQI 668 + L++SQ + L++ ++K E+E L + S++ KS LE Sbjct: 3135 EEKEFLIQSQNNRCIDLLNLTEKKNKEIETLQISNDSLNNSLTKSQMELREKSTLLENAK 3194 Query: 669 DALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMS 728 D ++ S ++LAL + L + +L T K MN + +MD +K+ Sbjct: 3195 DKITESNRKLAL-FDRLSANSSELNLTSSGRGIKKSSSMN-----LSTDMDSKNKIINQQ 3248 Query: 729 AEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVM 788 + I L + + T+ + ++Q I+ ++ +L+ + + Sbjct: 3249 EQTIIGLEQSLKVSKNEVDATKRELQKQLQNNKELQNQIKMTKEQFAKLEAKLQSVVKKL 3308 Query: 789 EDRRYSLER--KADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEH 846 D+ ++ +D + K S+ ++ ++L R+ ++ ++ ++ L + Sbjct: 3309 NDKDQRIDSLMSSDPNNKQTNQLNKQISDLNLENEKLKTRVDIITRENQSLKDDLESQKS 3368 Query: 847 ENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKAN---------RTDLAESESTKYQ 897 + +L + L E N + + ++ L+E+ N + + S+ + Sbjct: 3369 QKSKLDESCNALKTELINKKSIMDQYKEKLKELMEQINLKNKQISELKAEFNGSDDEDRK 3428 Query: 898 TQLRDLE-----SNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEK-YE 951 + ++ +E + LK I + + Q+K +I DLE + A + K L YE Sbjct: 3429 SYVKVIEQEGEITELKVIIDRQKKFVGQQKMKIADLEKNLKESNDEAQKMTKNLQTTIYE 3488 Query: 952 -----KNIEYVTQLEA-QLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTE 1005 +N+ +++ +L+E + IE+LN +E L K ++++ + + S + Sbjct: 3489 LEDRCQNLNQTIEMKNFRLRENEKTIEDLNKEIEFL-KGKIDILSREISMYSDNSSK--D 3545 Query: 1006 QYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQ 1065 I++I L + +KDE++ NN+ + + + ++ Q +++ ++E +M+ Sbjct: 3546 NLISKIVSLQKTVSEKDEQLNDAKINSNNS----LEIEDKMQQEIDQKNSRIHHLENQMR 3601 Query: 1066 -RVSKQLLDSKQHNEELQILVREQDDQIKELKE--TKLTFEMNIPKTEGMIISSTIEPMS 1122 ++K ++ + +++I +++ + ++ L+ + L E K++ + I+ Sbjct: 3602 VLLNKASHENAKEESKVKIDLKKANVKLSNLENDFSSLQEENAALKSKVSKLELVIKEKQ 3661 Query: 1123 DDANNVDXXXXXXXXXXXXLKVQ---EEEEFIQERSVLQEQSAKLNTELQECYTKIIQLE 1179 + N + LK + + E+F QE+S ++Q ++++ + K +L+ Sbjct: 3662 SEINIMAQKNNNDINEISELKSKLRKQNEDFTQEKSSAEKQRSEIDQLTNDLKAKNNELD 3721 Query: 1180 TLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELW 1239 +E+ + + +INQL+ + N + L +E S + + ++ E+ Sbjct: 3722 DSKSEIR----ILKSKINQLQQDFDAKN----HSLQKESEKLSQLEEKMKEKELELLNKS 3773 Query: 1240 KQHLAQREADFQKTEHELRVQLSAFESK------YEQLLDSVQSSTQEETNKIVTM---- 1289 + + +K ++E Q + K +Q+L+ + + E KI+T+ Sbjct: 3774 LDNDKAAKEIIEKLQNENLEQSKQLKKKEKDIEQMKQILNDLNNEQGELKGKIMTLQNDN 3833 Query: 1290 EQVTSLQN---KLQDKE-EHLRNLQEKYADVINQIE--ILRSEIEDEK-VAFXXXXXXXX 1342 EQ+T KL +K+ E L ++ K D I + I + ++ EK + Sbjct: 3834 EQITKTSQEKFKLNEKKSEELVSMINKLNDEIAEKNKTINGTLLQKEKEITKLKNDLEQS 3893 Query: 1343 XXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKV 1402 +L +E KQ+ + + +IN N +L + N+ + Sbjct: 3894 QITNERITNLESEMMKMKQLNDDLMNDINRYNEELIEKENELQELREKLIQSGNNLQKVT 3953 Query: 1403 LELTH-QLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKES-ELA 1460 E ++ L++K +E+ + L + +E N+ +L E+ Sbjct: 3954 PEQSYFDLQMKITELEDIIKDKNSQLENKTNEITNLYSKLYNTSPPSNSKKPRNTKLEVE 4013 Query: 1461 ILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTN 1520 +R+KM E E K+ + ++ +L +I ++ L + + + ++ + N Sbjct: 4014 KMRIKMAE----LENKNKDLIDQNTRMNSDLQAQINQNNKLKRHMKDNENNFNSQINQLN 4069 Query: 1521 -EMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKE 1579 ++Q + + E ++ L++ Q + QK+ S KQ + +L+N K Sbjct: 4070 LKLQKVVSDYEARLLILDNSKNQTQRVNELRERIKQKNEEILSKEKQINENKLENDKLKN 4129 Query: 1580 LLDAVPRAELDLAMYMLHQRDVR 1602 ++ + DL+ Y L Q++ + Sbjct: 4130 EIELSKKQNEDLSNY-LSQKEAK 4151 Score = 152 bits (369), Expect = 7e-35 Identities = 303/1522 (19%), Positives = 646/1522 (42%), Gaps = 164/1522 (10%) Query: 144 VTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQII-EAKNKATTXXXXXXXX 202 V L + I+ KD + L+ ++ + TI DL+ ++ K++ I + +NK Sbjct: 436 VDELKSIIRNKDKQIIELESEIDNQKATIEDLKIDVDFKERTISDLENKINVSANPDKGI 495 Query: 203 XXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEA 262 +K Q ++N I + E K + +L KDIE+KD +I + + + E Sbjct: 496 ELLKEEKDKAISKLQKQIERQNTIIQQNEEKID--QLSKDIEAKDQKIDEMIQKSLTAEV 553 Query: 263 ARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMT 322 + + KL Q L +A Q+ E ++ +IE+ LE Sbjct: 554 PSGDGAALELKL-QNLN-------------SYIAIQN-EKMGQKDAKIEQ---LEDERQK 595 Query: 323 ELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKM 382 TK EL L Q++ TN E K+A + + P K+G +S + K Sbjct: 596 NDTKISELTSTLT-QLKLTNNENTLKIAELENTIAKSNIPKKEGELYLSEVPQEVSFLKN 654 Query: 383 KSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXX 442 K + LN INK++ K I+ L +++V K I D Sbjct: 655 K-------NNMLN-----NINKSQAEK----IKHLEQEIVKKNKQIGSIDEMHKKSR--- 695 Query: 443 XGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLI 502 L Q+Q +++ + L G N+ ++ + K Q L +L ++K N+ +L Sbjct: 696 ----ELQRQIQ-DYENKLNAQQLESGGENSAELLSL-KQQSNLLNQLVADLKKQNI-ELK 748 Query: 503 EKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTE 562 + L++ ++Q++ + + N+ ++ + K K + + +S S + L + Sbjct: 749 KTLETKDKQLSSMMSDSLLVKDNLSEITAELASKNKIIHDYELRLNALSGSGNQFENLLQ 808 Query: 563 E-LHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLES 621 E L ++ + K +++ ++ + SD K + +++N + + ++ L Sbjct: 809 EKLTKIATMEKRINTMKSDIEKQKIEIATLNQDVSDKNKTIQQLQNKLKNKENSVQRLNG 868 Query: 622 QKFDL---VQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQ---------ID 669 + DL + E IL ++ + E+ L + Q D IK EE+ Sbjct: 869 EITDLRSRISEYEILNERQAK-ENALLNNKLKQKDVQIENIKEQPKEEEEKPKQVGFAKP 927 Query: 670 ALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSA 729 +L + + I+ + + + I + + +++L+ + + N + ++ +++ A Sbjct: 928 SLPPKESDQREFIKGSRSSGQLKFSPIATPPEENNNSLSQLEQFKKLNTTIKEQSQRLLA 987 Query: 730 E--KISELLAKIN-HEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIA 786 + KI L ++N Q K + + +I ++ +E+ + +L +S+I S Sbjct: 988 KDRKIDLLKQRLNDSNNQLKEIMETPENKRIAAKEKELEDFQQQL---RSQIISQSSSF- 1043 Query: 787 VMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVL-----MDHDRVVEKQL 841 + E ++D + +E + E T +++E++ +L + D+++++++ Sbjct: 1044 ------ITYENESDAMKQIKEENYRRVVENTHKDNEIIRLTKLLATDKTLKEDKILQEKI 1097 Query: 842 LEIE---HENKELQKKNQILLE----ENQNLQISLSDM-QQHYNALVEKANRTDLAESES 893 +++E + K+ K+ LE EN NLQ +++ + +Q E+AN + Sbjct: 1098 MQLEAKVQQMKDFNKETAANLESKNLENYNLQDNINSLKEQIQKQNDEQANHQKELDERD 1157 Query: 894 TKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYE-- 951 + +++E R E Q +I Q+K +L+++ N + E+ I ++ + E Sbjct: 1158 EQIAVLQKEIEKYENRYL-EQQEVISQEKLNNSNLKLKLN-EAENEIEKSHIVKQPGELY 1215 Query: 952 -----KNIEY-----------VTQLEAQLQEYKNNIENLNMNVEE---LNKMNLELIDK- 991 + I Y +TQ A+++E ++ IE N +E L K + EL + Sbjct: 1216 LSEVPQQISYFENKVKIMNGMITQSNAKIKELESQIEKKNKQIESTEALQKKSRELYRQI 1275 Query: 992 HVQKQQTQSPDYTEQYINEI-----NKLNALLKQKDE------EIIALN----QKINNAQ 1036 +Q+ S T + I E+ N+ N ++K KD+ EI+ +K Sbjct: 1276 RDYEQRLSSLGLTVEQIREMEMTIKNQAN-IIKAKDDDLKQTKEILEYREEQIEKFIAES 1334 Query: 1037 VSYMSMVSDYESKLAQFTTKLENMEEE-MQRVSKQLLDSKQHNEELQILVREQDDQIKEL 1095 VS + + ++++ LE ++E ++++ +++Q E+L ++E ++ I L Sbjct: 1335 VSIRDAIETLKQRISELEMLLEKKDKENNDKIAEIQEENRQTLEQLAKQLQEAEEDINVL 1394 Query: 1096 KETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLK---VQEEEEFIQ 1152 + +E I + + IE M++D +++ LK +EEE Q Sbjct: 1395 EGNCQVYEQEIAEKD-----KQIEQMTNDIKSLEEVINEQSNTIDSLKQDVATKEEEIKQ 1449 Query: 1153 ERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGH-DVVNQ--EQINQLKSKLEQLNTE 1209 + + E + + K +++ E+ H ++Q E I QL+S++EQ Sbjct: 1450 LKQTVSENEEVIKQLQTDIEQKDAEIQKNKEEIEQHKQTISQRDETIKQLQSEIEQHKQT 1509 Query: 1210 NDNLLSTVAELRSSIS---SAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQ---LSA 1263 + + + +L+++IS + Q EI E KQ +A+R+A+ QK + E+ Q +S Sbjct: 1510 IADKNNEIEQLKNTISEREETIKQLQNEI-EQHKQTMAERDAEIQKNKEEIEQQKQTISN 1568 Query: 1264 FESKYEQLLDSVQSSTQE-ETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADV--INQI 1320 ++ EQL ++ E E K E+ S++ + E+H + + ++ A++ + Q Sbjct: 1569 NNNEIEQLKKTISERDAEIEQLKKTIAERDESIKQLQNEIEQHKQTISQRDAEIEQLKQT 1628 Query: 1321 EILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQ---MQEQSILNINEENAQL 1377 R + EK D E + KQ ++++I + E Q Sbjct: 1629 VQQRDQTIAEKEDLIKQLQSEIEQHKQTISDKNNEIEQLKQTVNARDEAIKQLQSEIEQH 1688 Query: 1378 KKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENV 1437 K++ + + + + ++ +EI Q H+ TI +QR+ E E + Sbjct: 1689 KQTIAERDAEIQKNKEEIEQQKQTISQRDETIKQLQNEIEQ--HKQTI--SQRDAEIEQL 1744 Query: 1438 RQQLVEYEKRI---EDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIE-ELNV 1493 +Q + + ++ I EDL + +SE+ + + E + ++E E ++ + + + ++ Sbjct: 1745 KQTVQQSDQTIAEKEDLIKQLQSEIEQHKQTIAERDAEIQKNKEEIEQQKQTISQRDESI 1804 Query: 1494 KITES-VSLNKQ-VAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASS 1551 K +S + NKQ +A+ K +E+ E +++ + EI I ++ + Sbjct: 1805 KQMQSEIEQNKQTIADREKEIEQHKQTIAERDNSIKQLQEEIEQHKQTIAERDAEIQKNK 1864 Query: 1552 SKI-QKHVSFASDTKQGRDEQL 1572 +I QK+ + + T +G +++L Sbjct: 1865 EEIQQKNEAINALTNEGEEKRL 1886 Score = 124 bits (299), Expect = 2e-26 Identities = 231/1150 (20%), Positives = 494/1150 (42%), Gaps = 99/1150 (8%) Query: 464 SLIHVGTNTEDVNEIAKVQEQL------KQELNDEIKDVNVKDLIEKLKSAEEQ--ITQL 515 S +H N + E+ K++EQ+ K E +++ V + + + K +E Q + QL Sbjct: 289 SNLHELDNNQLQGELIKLREQILELSKQKSETESKLEWVEQSNKLLQSKPSENQQILDQL 348 Query: 516 ND----EIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNK--EIVRLTEELHHLSQ 569 N EID K++ ++ + KL + QK ID+ K+ +S+ E L +E ++L Sbjct: 349 NTLRQKEIDEQQKHVEELTNQEKLAESEYQKQIDHLKKLLESSNAAETENLRKENNNLRD 408 Query: 570 KVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQE 629 ++A + K ++++ + D+ K+ E++++ + K I LES+ + Sbjct: 409 QLAAIASNK-----NILENEEILTSNFDLSDKVDELKSIIRNKDKQIIELESEIDNQKAT 463 Query: 630 LHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHL--EEQIDALSASKKELALVIENLKL 687 + L+ D E ++D+ + + + K + L EE+ A+S +K++ ++ Sbjct: 464 IEDLKIDVDFKERTISDLEN-KINVSANPDKGIELLKEEKDKAISKLQKQIERQNTIIQQ 522 Query: 688 DKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKI 747 ++E++ KD+E + K+ IQ++ LT ++ + L +N S I Sbjct: 523 NEEKIDQLSKDIEAKDQ----KIDEMIQKS--LTAEVPSGDGAALELKLQNLN----SYI 572 Query: 748 QTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQ 807 Q + K+ ++D IE +E E K ++I L ++ ++ K +L + + Sbjct: 573 AIQ---NEKMGQKDAKIEQLEDERQKNDTKISELTSTLTQLKLTNNENTLKIAELENTIA 629 Query: 808 EKQKAYSEYTIQEDELVNRLAVLMDHDRVV----EKQLLEIEHENKELQKKN-QI----- 857 + E + E+ ++ L + + ++ + Q +I+H +E+ KKN QI Sbjct: 630 KSNIPKKEGELYLSEVPQEVSFLKNKNNMLNNINKSQAEKIKHLEQEIVKKNKQIGSIDE 689 Query: 858 LLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQ-LRDLESNLKRITHEHQT 916 + ++++ LQ + D + NA ++ + AE S K Q+ L L ++LK+ E + Sbjct: 690 MHKKSRELQRQIQDYENKLNAQQLESGGENSAELLSLKQQSNLLNQLVADLKKQNIELKK 749 Query: 917 LIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNM 976 + K K++ + + ++ L K + +Y +L A L N ENL Sbjct: 750 TLETKDKQLSSMMSDSLLVKDNLSEITAELASKNKIIHDYELRLNA-LSGSGNQFENLLQ 808 Query: 977 NVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQ 1036 E+L K + ++K + T D +Q I EI LN + K++ I L K+ N + Sbjct: 809 --EKLTK--IATMEKRI---NTMKSDIEKQKI-EIATLNQDVSDKNKTIQQLQNKLKNKE 860 Query: 1037 VSYMSM---VSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIK 1093 S + ++D S+++++ E +E ++ +L E ++ +E++++ K Sbjct: 861 NSVQRLNGEITDLRSRISEYEILNERQAKENALLNNKLKQKDVQIENIKEQPKEEEEKPK 920 Query: 1094 EL---------KETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKV 1144 ++ KE+ + ++ G + S I ++ NN +K Sbjct: 921 QVGFAKPSLPPKESDQREFIKGSRSSGQLKFSPIATPPEENNNSLSQLEQFKKLNTTIKE 980 Query: 1145 QEEEEFIQERSV--LQEQSAKLNTELQECY--TKIIQLETLNTELTGHDVVNQEQINQLK 1200 Q + ++R + L+++ N +L+E + ++ EL + QI Sbjct: 981 QSQRLLAKDRKIDLLKQRLNDSNNQLKEIMETPENKRIAAKEKELEDFQQQLRSQIISQS 1040 Query: 1201 SKLEQLNTENDNLLSTVAE-LRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRV 1259 S E+D + E R + + + EI L K + K E + Sbjct: 1041 SSFITYENESDAMKQIKEENYRRVVENT--HKDNEIIRLTKLLATDKTLKEDKILQEKIM 1098 Query: 1260 QLSAFESKYEQLLD-SVQSSTQEETNKIVT---MEQVTSLQNKLQDKEEHLRNLQEKYAD 1315 QL E+K +Q+ D + +++ E+ + + + SL+ ++Q + + N Q++ + Sbjct: 1099 QL---EAKVQQMKDFNKETAANLESKNLENYNLQDNINSLKEQIQKQNDEQANHQKELDE 1155 Query: 1316 VINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEE-- 1373 QI +L+ EIE + + N++ ++++ I+ E Sbjct: 1156 RDEQIAVLQKEIEKYENRYLEQQEVISQEKLNNSNLKLKLNEAENEIEKSHIVKQPGELY 1215 Query: 1374 NAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDE 1433 +++ + + + AK+ EL Q+E K+ +I E T L +++ E Sbjct: 1216 LSEVPQQISYFENKVKIMNGMITQSNAKIKELESQIEKKNKQI-----ESTEALQKKSRE 1270 Query: 1434 FENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNV 1493 + +Q+ +YE+R+ L E ++ + + + AN + K+ ++++ K I E Sbjct: 1271 ---LYRQIRDYEQRLSSLGLTVE-QIREMEMTIKNQANIIKA--KDDDLKQTKEILEYRE 1324 Query: 1494 KITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSK 1553 + E + + A+E + +E++ LE ++ E ND+I +Q R + + Sbjct: 1325 EQIE--KFIAESVSIRDAIETLKQRISELEMLLEKKDKE---NNDKIAEIQEENRQTLEQ 1379 Query: 1554 IQKHVSFASD 1563 + K + A + Sbjct: 1380 LAKQLQEAEE 1389 Score = 114 bits (274), Expect = 2e-23 Identities = 151/773 (19%), Positives = 351/773 (45%), Gaps = 60/773 (7%) Query: 324 LTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKK-GSPLISRKSGRNTASKM 382 L KI++L + N +N ++ + + K VS ++ I+ + KM Sbjct: 3524 LKGKIDILSR-EISMYSDNSSKDNLISKIVSLQKTVSEKDEQLNDAKINSNNSLEIEDKM 3582 Query: 383 KSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNK-DLVDKEYVISEKDTXXXXXXXX 441 + Q +S + + ++ N+ + +S K DL +S + Sbjct: 3583 QQEIDQKNSRIHHLENQMRVLLNKASHENAKEESKVKIDLKKANVKLSNLENDFSSLQEE 3642 Query: 442 XXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDL 501 + +++L+L ++ +++ N D+NEI++++ +L+++ D ++ K Sbjct: 3643 NAALKSKVSKLELVIKEKQSEINIM-AQKNNNDINEISELKSKLRKQNEDFTQE---KSS 3698 Query: 502 IEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLT 561 EK +S +I QL +++ A N + KS ++ LK SK++ ++ Sbjct: 3699 AEKQRS---EIDQLTNDLKAKNNELDDSKSEIRI-LK---------SKINQLQQDFDAKN 3745 Query: 562 EELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLES 621 L S+K+++LEE+ +L L++ + +++D K I +E L L+ L+ Sbjct: 3746 HSLQKESEKLSQLEEKMKEKELELLN----KSLDNDKAAKEI-IEKLQNENLEQSKQLKK 3800 Query: 622 QKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALV 681 ++ D+ Q IL +E + I LQ+D +I +E+ +EL + Sbjct: 3801 KEKDIEQMKQILNDLNNEQGELKGKIMTLQNDN--EQITKTS-QEKFKLNEKKSEELVSM 3857 Query: 682 IENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKIS------EL 735 I L + + TI KE + KL+N ++++ +++ + +E + +L Sbjct: 3858 INKLNDEIAEKNKTINGTLLQKEKEITKLKNDLEQSQITNERITNLESEMMKMKQLNDDL 3917 Query: 736 LAKINHEEQSKIQTQFGIDA---KIQERDLYIENIESELSKYKSRICRLEESIAVMEDRR 792 + IN + I+ + + K+ + ++ + E S + ++ ++ E +++D+ Sbjct: 3918 MNDINRYNEELIEKENELQELREKLIQSGNNLQKVTPEQSYFDLQM-KITELEDIIKDKN 3976 Query: 793 YSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQ 852 LE K +++ + K Y+ + + ++ R+ ++ E+E++NK+L Sbjct: 3977 SQLENKTNEITNLYS---KLYNTSPPSNSKKPRNTKLEVEKMRI---KMAELENKNKDLI 4030 Query: 853 KKN-------QILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLES 905 +N Q + +N L+ + D + ++N+ + + N + + + D Sbjct: 4031 DQNTRMNSDLQAQINQNNKLKRHMKDNENNFNSQINQLNLKLQKVVSDYEARLLILDNSK 4090 Query: 906 NLKRITHEHQTLIVQKKKEIEDLEIEFN-TQIES-AIRDKKVLNEKYEKNIE-YVTQLEA 962 N + +E + I QK +EI E + N ++E+ ++++ L++K +++ Y++Q EA Sbjct: 4091 NQTQRVNELRERIKQKNEEILSKEKQINENKLENDKLKNEIELSKKQNEDLSNYLSQKEA 4150 Query: 963 QLQEYKNNIENL---NMNVE-ELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALL 1018 +++E + I++L N +E ELNK ++ ++ + + D +EQ N + + + L Sbjct: 4151 KIKELERRIQSLDEQNAKIEDELNK-SINKNEEINKSSIIERTDLSEQLNNALKENSRLK 4209 Query: 1019 KQKDEEIIALNQKIN-NAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQ 1070 Q DE + + + + ++ ++ + +VSD L+++ L++ EE++ + Q Sbjct: 4210 VQIDETVSKIKELCDKDSDIARVKLVSDQLIDLSEYCKLLKDQNEELKNMISQ 4262 Score = 86.2 bits (204), Expect = 7e-15 Identities = 181/929 (19%), Positives = 393/929 (42%), Gaps = 87/929 (9%) Query: 696 IKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDA 755 ++DL +K N N +N + + +++ A+ + + I++ E G D Sbjct: 16 VQDLRINKSQ--NSKMNESGQNSQIVED-DEVPAQLVDDSQLNISNIEAPNTNDTSGFDQ 72 Query: 756 KIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSE 815 +++ + S S+ ++ ++EESI + + R S + ++ L + +++ Sbjct: 73 RLKLSQGTRRTVRSA-SQILNQSPQIEESITLADSRDLSAIMSSKEIFDELNAIRNQFTD 131 Query: 816 ----YTIQEDELVNRLAVLMD-HDRVVEKQLL--EI-EHENKELQKKNQI---------L 858 Y+ +L N + L + + + ++ EI +++ L +N I L Sbjct: 132 IDDFYSSDNQKLRNLVNALESLKNNLTNESIITHEISQNDGDTLISRNVINTNASFAAEL 191 Query: 859 LEENQNLQISLSDMQQHYNALVEKANRTDLAESEST----KYQTQLRDLESN--LKRITH 912 L EN+ L + + Q N L K + E++ KY+ +L +L +N L I Sbjct: 192 LNENEKLYLENRSLLQLKNELRAKNLKIIQIENDFRNRLRKYKHKLDELSNNEILDNILR 251 Query: 913 EH-QTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNI 971 E QT + + E I N ++ ++ N ++ QL+ +L + + I Sbjct: 252 EKLQTRDMVQSVAQEQYAILHNFEVSKSLTRPNGNNSSNLHELDN-NQLQGELIKLREQI 310 Query: 972 ENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNAL-LKQKDEEIIALNQ 1030 L+ E + LE +++ + Q++ P +Q ++++N L + ++ + + L Sbjct: 311 LELSKQKSE-TESKLEWVEQSNKLLQSK-PSENQQILDQLNTLRQKEIDEQQKHVEELTN 368 Query: 1031 KINNAQVSYMSMVSDYESKLAQFTT--KLENMEEEMQRVSKQLL---DSKQHNEELQILV 1085 + A+ Y + D+ KL + + + EN+ +E + QL +K E +IL Sbjct: 369 QEKLAESEYQKQI-DHLKKLLESSNAAETENLRKENNNLRDQLAAIASNKNILENEEILT 427 Query: 1086 REQD--DQIKELKETKLTFEMNIPKTEGMIIS--STIEPMSDDANNVDXXXXXXXXXXXX 1141 D D++ ELK + I + E I + +TIE + D VD Sbjct: 428 SNFDLSDKVDELKSIIRNKDKQIIELESEIDNQKATIEDLKID---VDFKERTISDLENK 484 Query: 1142 LKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKS 1201 + V + + +L+E+ K ++LQ+ Q+E NT + N+E+I+QL Sbjct: 485 INVSANPD--KGIELLKEEKDKAISKLQK------QIERQNTIIQQ----NEEKIDQLSK 532 Query: 1202 KLEQLNTENDNLL--STVAELRSSISSAVD---QRGFEIAELWKQHLAQREADFQKTEHE 1256 +E + + D ++ S AE+ S +A++ Q + + + Q++A ++ E E Sbjct: 533 DIEAKDQKIDEMIQKSLTAEVPSGDGAALELKLQNLNSYIAIQNEKMGQKDAKIEQLEDE 592 Query: 1257 LRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQN-KLQDKEEHLRNLQEKYAD 1315 R + S+ L ++ + E T KI +E + N ++ E +L + ++ + Sbjct: 593 -RQKNDTKISELTSTLTQLKLTNNENTLKIAELENTIAKSNIPKKEGELYLSEVPQEVSF 651 Query: 1316 VINQIEILRS--EIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSY-KQMQE-QSILNIN 1371 + N+ +L + + + EK+ ++ +++ +Q+Q+ ++ LN Sbjct: 652 LKNKNNMLNNINKSQAEKIKHLEQEIVKKNKQIGSIDEMHKKSRELQRQIQDYENKLNAQ 711 Query: 1372 EENAQLKKSSXXXXXXXXXXXXR--VNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQ 1429 + + + S+ V D + + +EL LE KD ++ + + Sbjct: 712 QLESGGENSAELLSLKQQSNLLNQLVADLKKQNIELKKTLETKDKQLSSMMSDSLLV--- 768 Query: 1430 RNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLK-MHENANHYETMQKESEIERVKLI 1488 D + +L K I D YE LRL + + N +E + +E + + Sbjct: 769 -KDNLSEITAELASKNKIIHD--YE-------LRLNALSGSGNQFENLLQEKLTKIATME 818 Query: 1489 EELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMV- 1547 + +N ++ ++A LN+ + ++ ++Q L+N+E + LN EIT+L++ + Sbjct: 819 KRINTMKSDIEKQKIEIATLNQDVSDKNKTIQQLQNKLKNKENSVQRLNGEITDLRSRIS 878 Query: 1548 --RASSSKIQKHVSFASDTKQGRDEQLDN 1574 + + K + ++ + +D Q++N Sbjct: 879 EYEILNERQAKENALLNNKLKQKDVQIEN 907 Score = 51.6 bits (118), Expect = 2e-04 Identities = 110/623 (17%), Positives = 251/623 (40%), Gaps = 33/623 (5%) Query: 99 KQKEILMEKIKQYKELSKRSST-TIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNA 157 KQ EI + K ++++ S + +R Q ++ L+N +K K+N Sbjct: 3660 KQSEINIMAQKNNNDINEISELKSKLRKQNEDFTQEKSSAEKQRSEIDQLTNDLKAKNNE 3719 Query: 158 LSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQ 217 L + +++I+++ I LQ+ + K+ ++ +++ + D + Sbjct: 3720 LDDSKSEIRILKSKINQLQQDFDAKNHSLQKESEKLSQLEEKMKEKELELLNKSLDNDKA 3779 Query: 218 MTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQE 277 ++ E E + ++ KDIE ++ L L+ + ++ ++ + Sbjct: 3780 AKEIIEKLQNENLEQSKQLKKKEKDIEQMKQILNDLNNEQGELKGKIMTLQNDNEQITKT 3839 Query: 278 LEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTK-KIELLEHLNC 336 ++ + + + E+ I G+L + E+TK K +L + Sbjct: 3840 SQEKFKLNEKKSEELVSMINKLNDEIAEKNKTI--NGTL-LQKEKEITKLKNDLEQSQIT 3896 Query: 337 QIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSG-RNTASKMKSPWSQLSSETLN 395 R TN E E + ++ ++ LI +++ + K+ + L T Sbjct: 3897 NERITNLESE-MMKMKQLNDDLMNDINRYNEELIEKENELQELREKLIQSGNNLQKVTPE 3955 Query: 396 QDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLE 455 Q + +I +LE +I+ N L +K I+ + K +L++E Sbjct: 3956 QSYFDL--QMKITELEDIIKDKNSQLENKTNEITNLYSKLYNTSPPSNSKKPRNTKLEVE 4013 Query: 456 HQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQL 515 + ++ L N + +++ ++ L+ ++N K L +K E Sbjct: 4014 -KMRIKMAEL--ENKNKDLIDQNTRMNSDLQAQINQNNK------LKRHMKDNE---NNF 4061 Query: 516 NDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELE 575 N +I+ N + KV S+++ +L + + + +V++ + I + EE+ +++ E + Sbjct: 4062 NSQINQLNLKLQKVVSDYEARLLILDNSKNQTQRVNELRERIKQKNEEILSKEKQINENK 4121 Query: 576 EEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQ 635 E L+ + + + D+ + + E + + I L+ Q + EL+ Sbjct: 4122 LENDKLKNEI---ELSKKQNEDLSNYLSQKEAKIKELERRIQSLDEQNAKIEDELNKSIN 4178 Query: 636 KYDEV-EDKLADISQLQSDQVCSEIK-SVHLEEQIDALSASKKELA---LVIENLKLDKE 690 K +E+ + + + + L S+Q+ + +K + L+ QID + KEL I +KL + Sbjct: 4179 KNEEINKSSIIERTDL-SEQLNNALKENSRLKVQIDETVSKIKELCDKDSDIARVKLVSD 4237 Query: 691 QLYGT---IKDLENDKEDIMNKL 710 QL K L++ E++ N + Sbjct: 4238 QLIDLSEYCKLLKDQNEELKNMI 4260 >UniRef50_UPI000049A29E Cluster: Viral A-type inclusion protein repeat; n=2; Entamoeba histolytica HM-1:IMSS|Rep: Viral A-type inclusion protein repeat - Entamoeba histolytica HM-1:IMSS Length = 1813 Score = 214 bits (522), Expect = 2e-53 Identities = 312/1490 (20%), Positives = 644/1490 (43%), Gaps = 145/1490 (9%) Query: 143 DVTHLSNTIKEKDNALS-VLQVKMKIME--TTILDLQEKI-NEKDQII---EAKNKATTX 195 ++T L +K+N L+ V K +++E T + EKI NE Q+ E K Sbjct: 276 ELTQLKTDNDQKENELNQVRHEKDEVIEKFNTSKEENEKIMNELSQLKQEKEEKENELKE 335 Query: 196 XXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEE 255 + ++K+ E + E K+E L I+ + RI EE Sbjct: 336 QVKKMEEEKSKLITELSNGSDGISKLNEELTQTKQE-KEEINNELNSIKEEKKRIE--EE 392 Query: 256 ANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGS 315 N+++ + EI E K+ +E ++ L + I EIEEK Sbjct: 393 KNQIINENK-EIKEEKEKIEEEKKELLKEIEKEKEGNNQLQNE-INTIQTRMKEIEEKNQ 450 Query: 316 LEIA-NMTELTKKIELLEHLNCQIRQTNKELE------NKLATMGTESKAVSSPSKKGSP 368 I N E+ K E E+L ++ Q +E + N+L + T+ + + K+ Sbjct: 451 EIICDNNKEIAKFKEEQENLQKELNQIKEEKQKTENEKNELVDVKTQKENELNKLKEEKE 510 Query: 369 LI--SRKSGRNTASKMKSPWSQLSSE--TLNQDTDKKINKNEIAKLEMVIQSLNKDLVDK 424 I + + N+ +++ ++L+ E ++ Q+ D N +LE+ + K+ + Sbjct: 511 QIFNEKTTIENSLNQIVEEKNKLTEEKESIKQELDSIKADNSTKELEINKINEEKNQLQN 570 Query: 425 EY--VISEKDTXXXXXXXXXXGKDTLIAQLQL--EHQQHMEGPS---LIHVGTNTEDVNE 477 +Y V EK+ K +L E +Q +E + + + + + Sbjct: 571 DYDTVQQEKENIQKELNQIKIEKSQKEEELNKIKEEKQQVEDEKAKLITDIANGNDGLTK 630 Query: 478 IAKVQEQLKQE---LNDEIKDV-NVKDLIE-KLKSAEEQITQLNDEIDAANKNMIKVKSN 532 + +V ++LK E +++E+ + N +D I + +E+I Q +E N+ V N Sbjct: 631 LNEVIDKLKDEKENISNELNQIKNERDNISNEFNKTKEEIKQKENETIQLNEEK-SVLLN 689 Query: 533 HKLKLKQMQKTIDNFSKVSDSNKE--IVRLTEELHHLSQKVAELEEEKGNLQLHLVDY-D 589 ++K+ ++ I++ V KE I +L E+ + ++ +++ EK ++ L D Sbjct: 690 ELNQIKEEKQKIEDEKAVIQQEKENEITKLNEDKTVIENELNQIKTEKQEIENELNQTKD 749 Query: 590 SGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQ 649 + IE + K + E+ N + IS L + QE + + ++++++ A + Sbjct: 750 EKQKIEDEKSKLITELSNGND----GISKLNEELTQTKQEKENVLNELNQIKNEFASFKE 805 Query: 650 LQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNK 709 Q+ Q +E+K + + Q + L E++ + E +L T ++LE K++I+ Sbjct: 806 -QNTQKENELKDENNKVQQE-LEQKNNEVSKLEEEKGNISNELSNTKQELEQKKQEIITI 863 Query: 710 LQNYIQENMDLTDKLEKMSAEK---ISEL------LAKINHEEQSKIQTQFGIDAKIQER 760 Q ++ +L ++++K+ EK I+EL ++K+N E Q + I ++E Sbjct: 864 TQEKEEKENELKEQVKKIEEEKSKLITELSNGSDGISKLNEELTQTKQEKEEIQKALEEE 923 Query: 761 DLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTI-- 818 +E IE+EL + K LEE ++ ++E K + L L E +K E T Sbjct: 924 KEKLERIETELKEIKEAKQELEE------EKNKTIEEKTN-LQQELNENKKIVEELTQTK 976 Query: 819 -QEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEEN-QNLQISLSDMQQHY 876 +++E+ N L + + + +E++ +I +ENKE++++N +EE Q + + +++ Sbjct: 977 QEKEEINNELNSIKEEKKRIEEEKNQIINENKEIKEENIKSIEEKTQEINSLTTSIEELK 1036 Query: 877 NALVEKANRTDLAESESTKYQTQLRDLE---SNLKRITHEHQTLIVQKKKEIEDLEIEFN 933 L E E E + ++L D++ +K+ E + + +K E E E Sbjct: 1037 GRLEESKGERIEIEKERDRVISELNDIKLQNEGMKKQVEEAHNRMTEMQKSFEGSENEMI 1096 Query: 934 TQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHV 993 + + I LNEK ++ E V L+ QL + N+N+EE+ K +E +K+ Sbjct: 1097 NSLNNQITQ---LNEKEKQMNEQVMALQTQLSQS-------NINLEEVKKDLIESQNKYT 1146 Query: 994 QKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQF 1053 Q + + D EQ E NK+N K +EE+ +++N+ Q Y + + + + Sbjct: 1147 QINEEK--DCVEQ---ERNKINEEYKTVNEELEKNKKELNDLQTKYDNEILELNKNKDEL 1201 Query: 1054 TTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMI 1113 + + N++EE + +Q+ ++ +L + D + +L E E+ K E Sbjct: 1202 NSLINNLKEEKTNLEEQVKKMEEEKSKLITELSNGSDGVSKLNE-----ELTQTKQEKEE 1256 Query: 1114 ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQE--QSAKLNTELQEC 1171 I++ + + ++ ++ +K ++E+ +++ +L+E + + N +LQ Sbjct: 1257 INNELNSIKEEKKRIEEEKNQIINENKEIKEEKEKIEEEKKELLKEIEKEKEGNNQLQN- 1315 Query: 1172 YTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQR 1231 ++ T+ T + + NQE I ++ + E +NL + +++ S + Sbjct: 1316 -----EINTIQTRMKEIEEKNQEIICDNNKEIAKFKEEQENLQKELNQIKEEKSKLITDL 1370 Query: 1232 GFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQ 1291 L K L + K + +R +L + + + ++ D ++ QE +K+ E+ Sbjct: 1371 SNGNDGLSK--LNEEIETINKEKEGIRKELESLKEENNKIQDELEQKNQE-LSKV--KEE 1425 Query: 1292 VTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXD 1351 L + L + + + L E +NQI+ + E+ ++ V + Sbjct: 1426 KEKLIHDLTNGNDGINQLNED----LNQIKNDKEELTEKNVQLQNEINKLKSENEELSNN 1481 Query: 1352 LRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLEL 1411 L E + KQ+ E+ + I EE +L K ++ + + KV E +L Sbjct: 1482 LSFEKEGLKQVNEE-VNAIKEERDELVKQ-----------IKKIEEEKRKVEE---ELNF 1526 Query: 1412 KDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENAN 1471 SE+ ++ + Q N E ++Q L E + +IE++ EKES Sbjct: 1527 NGSEVNEQIAQINNEKEQLNQECNELKQNLKELQSKIEEIEQEKES-------------- 1572 Query: 1472 HYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEI 1531 +EI++ + ++EL +ITE + K + E + +E+E+ + E + N Sbjct: 1573 --------NEIKKKEELQELQEEITEKDNDIKNLKEEIERIEKELQEKEEDMEQMSNNTE 1624 Query: 1532 EIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQG---RDEQLDNTMNK 1578 E+ L +++T Q ++ + + + +TK+ ++++N MNK Sbjct: 1625 ELEELKNKLTETQRLLEEEKKEKESISNEFEETKEQVLVELQRVNNEMNK 1674 Score = 202 bits (492), Expect = 8e-50 Identities = 259/1300 (19%), Positives = 576/1300 (44%), Gaps = 111/1300 (8%) Query: 319 ANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSS--PSKKGSPLISRKSGR 376 +++ T E+ +N QI + NK L+N+ + + A S +K S + ++K Sbjct: 163 SSLASETTAEEVNRSVNAQIEEENKRLQNENEELKKKCDAQDSLLKTKMKSEMEAKKKVE 222 Query: 377 NTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXX 436 ++ K ++++E D K+N+ E+ +++ +S+N +L+ + EK++ Sbjct: 223 ILENEKKDLIDKMANEN---DGMSKLNE-ELTQIKNEKESINNELIQTK---QEKESINN 275 Query: 437 XXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDV 496 D + +L +H + + T+ E+ +I QLKQE K+ Sbjct: 276 ELTQLKTDNDQ--KENELNQVRHEKDEVIEKFNTSKEENEKIMNELSQLKQE-----KEE 328 Query: 497 NVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKL-KLKQMQKTIDNFSKVSDSNK 555 +L E++K EE+ ++L E+ + + K+ N +L + KQ ++ I+N +++ + Sbjct: 329 KENELKEQVKKMEEEKSKLITELSNGSDGISKL--NEELTQTKQEKEEINN--ELNSIKE 384 Query: 556 EIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKA 615 E R+ EE + + + E++EEK ++ + E + ++ N +TR+K Sbjct: 385 EKKRIEEEKNQIINENKEIKEEKEKIEEEKKELLKEIEKEKEGNNQLQNEINTIQTRMKE 444 Query: 616 ISLLESQKFDLVQELHILQQKYDEVEDKLA-DISQLQSDQVCSEIKSVHLEEQIDALSAS 674 I E + +++ + + K+ E ++ L +++Q++ ++ +E + E +D + Sbjct: 445 I---EEKNQEIICDNNKEIAKFKEEQENLQKELNQIKEEKQKTENEK---NELVDVKTQK 498 Query: 675 KKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISE 734 + EL LK +KEQ++ +EN I+ + +E + +L+ + A+ ++ Sbjct: 499 ENEL----NKLKEEKEQIFNEKTTIENSLNQIVEEKNKLTEEKESIKQELDSIKADNSTK 554 Query: 735 LLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYS 794 L +IN + K Q Q D QE+ ENI+ EL++ K + EE + +++ + Sbjct: 555 EL-EINKINEEKNQLQNDYDTVQQEK----ENIQKELNQIKIEKSQKEEELNKIKEEKQQ 609 Query: 795 LERKADQL-------GSYLQEKQKAYSEYTIQEDELVNRL-AVLMDHDRV------VEKQ 840 +E + +L L + + + +++ + N L + + D + +++ Sbjct: 610 VEDEKAKLITDIANGNDGLTKLNEVIDKLKDEKENISNELNQIKNERDNISNEFNKTKEE 669 Query: 841 LLEIEHENKELQKKNQILL-------EENQNLQISLSDMQQHYNALVEKANRTD-LAESE 892 + + E+E +L ++ +LL EE Q ++ + +QQ + K N + E+E Sbjct: 670 IKQKENETIQLNEEKSVLLNELNQIKEEKQKIEDEKAVIQQEKENEITKLNEDKTVIENE 729 Query: 893 STKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEK 952 + +T+ +++E+ L + E Q + +K K I +L N I + ++ E Sbjct: 730 LNQIKTEKQEIENELNQTKDEKQKIEDEKSKLITELS-NGNDGISKLNEELTQTKQEKEN 788 Query: 953 NIEYVTQLEAQLQEYKN-NIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEI 1011 + + Q++ + +K N + N +E NK+ EL K+ + + + + NE+ Sbjct: 789 VLNELNQIKNEFASFKEQNTQKENELKDENNKVQQELEQKNNEVSKLE--EEKGNISNEL 846 Query: 1012 NKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQL 1071 + L+QK +EII + Q+ + V E + ++ T+L N + + +++++L Sbjct: 847 SNTKQELEQKKQEIITITQEKEEKENELKEQVKKIEEEKSKLITELSNGSDGISKLNEEL 906 Query: 1072 LDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXX 1131 +KQ EE+Q + E+ ++++ + ET+L E+ K E + ++ N+ Sbjct: 907 TQTKQEKEEIQKALEEEKEKLERI-ETELK-EIKEAKQE---LEEEKNKTIEEKTNLQQ- 960 Query: 1132 XXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHD-V 1190 ++ E ++ ++E + +++ ++N EL + ++E ++ + Sbjct: 961 -----------ELNENKKIVEELTQTKQEKEEINNELNSIKEEKKRIEEEKNQIINENKE 1009 Query: 1191 VNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADF 1250 + +E I ++ K +++N +L +++ EL+ + + +R EI E + + D Sbjct: 1010 IKEENIKSIEEKTQEIN----SLTTSIEELKGRLEESKGER-IEI-EKERDRVISELNDI 1063 Query: 1251 QKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQ 1310 + ++ Q+ ++ ++ S + S E N + Q+T L K + E + LQ Sbjct: 1064 KLQNEGMKKQVEEAHNRMTEMQKSFEGSENEMINSL--NNQITQLNEKEKQMNEQVMALQ 1121 Query: 1311 EKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNI 1370 + ++Q I E++ + + + N+ YK + E+ N Sbjct: 1122 TQ----LSQSNINLEEVKKDLIESQNKYTQINEEKDCVEQERNKINEEYKTVNEELEKNK 1177 Query: 1371 NEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQR 1430 E N L+ +N + E LE + ++ ++ + L+ Sbjct: 1178 KELN-DLQTKYDNEILELNKNKDELNSLINNLKEEKTNLEEQVKKMEEEKSKLITELSNG 1236 Query: 1431 NDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEE 1490 +D + ++L + ++ E++ E S + + ++ E N KE + E+ K IEE Sbjct: 1237 SDGVSKLNEELTQTKQEKEEINNELNS-IKEEKKRIEEEKNQIINENKEIKEEKEK-IEE 1294 Query: 1491 LNVKITESVSLNKQVAELNKALEEEV--AKTNEMQTALENQEI------EIVTLNDEITN 1542 ++ + + K E N L+ E+ +T + +NQEI EI +E N Sbjct: 1295 EKKELLKEIEKEK---EGNNQLQNEINTIQTRMKEIEEKNQEIICDNNKEIAKFKEEQEN 1351 Query: 1543 LQ---NMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKE 1579 LQ N ++ SK+ +S +D +E+++ T+NKE Sbjct: 1352 LQKELNQIKEEKSKLITDLSNGNDGLSKLNEEIE-TINKE 1390 Score = 190 bits (464), Expect = 2e-46 Identities = 301/1493 (20%), Positives = 639/1493 (42%), Gaps = 132/1493 (8%) Query: 151 IKEKDNALSVLQVKMKIMETTILDLQEKI-NEKDQIIEAKNKATTXXXXXXXXXXXXXXX 209 +K K + + K++I+E DL +K+ NE D + + + T Sbjct: 207 LKTKMKSEMEAKKKVEILENEKKDLIDKMANENDGMSKLNEELTQIKNEKESINNELI-- 264 Query: 210 XXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDI--ESKDV--RISSLEEANKLLEAARF 265 TKQ+ + ++ + D+K+ L + E +V + ++ +E N+ + Sbjct: 265 ---QTKQEKESINNELTQLKTD-NDQKENELNQVRHEKDEVIEKFNTSKEENEKIMNELS 320 Query: 266 EISLEHSKLAQEL-EQXXXXXXXXXXXXXXLAKQS--IEPSCEEKTEI-EEKGSL--EIA 319 ++ E + EL EQ L+ S I EE T+ +EK + E+ Sbjct: 321 QLKQEKEEKENELKEQVKKMEEEKSKLITELSNGSDGISKLNEELTQTKQEKEEINNELN 380 Query: 320 NMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTA 379 ++ E K+IE E N QI NKE++ + + E K + +K +N Sbjct: 381 SIKEEKKRIE--EEKN-QIINENKEIKEEKEKIEEEKKELLKEIEKEKE--GNNQLQNEI 435 Query: 380 SKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXX 439 + +++ ++ E NQ+ NK EIAK + ++L K+L + + + Sbjct: 436 NTIQTRMKEI--EEKNQEIICDNNK-EIAKFKEEQENLQKELNQIKEEKQKTENEKNELV 492 Query: 440 XXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTN--TEDVNEIAKVQEQLKQELNDEIKDVN 497 K+ + +L+ E +Q + I N E+ N++ + +E +KQEL+ D + Sbjct: 493 DVKTQKENELNKLKEEKEQIFNEKTTIENSLNQIVEEKNKLTEEKESIKQELDSIKADNS 552 Query: 498 VKDL-IEKLKSAEEQITQLNDEIDAANKNMIK----VKSNHKLKLKQMQKTIDNFSKVSD 552 K+L I K+ + Q+ D + +N+ K +K K +++ K + +V D Sbjct: 553 TKELEINKINEEKNQLQNDYDTVQQEKENIQKELNQIKIEKSQKEEELNKIKEEKQQVED 612 Query: 553 SNKEIV----RLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENL 608 +++ + L L++ + +L++EK N+ L + R S+ + K E + Sbjct: 613 EKAKLITDIANGNDGLTKLNEVIDKLKDEKENISNELNQIKNERDNISNEFNKT--KEEI 670 Query: 609 AETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVC--SEIKSVHLEE 666 + + I L E +K L+ EL+ ++++ ++ED+ A I Q + +++ +E K+V +E Sbjct: 671 KQKENETIQLNE-EKSVLLNELNQIKEEKQKIEDEKAVIQQEKENEITKLNEDKTV-IEN 728 Query: 667 QIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEK 726 +++ + K+E+ + K +K+++ E++K ++ +L N L ++L + Sbjct: 729 ELNQIKTEKQEIENELNQTKDEKQKI-------EDEKSKLITELSNGNDGISKLNEELTQ 781 Query: 727 MSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIEN--IESELSKYKSRICRLEES 784 EK +L ++N + F +E +L EN ++ EL + + + +LEE Sbjct: 782 TKQEK-ENVLNELNQIKNEF--ASFKEQNTQKENELKDENNKVQQELEQKNNEVSKLEEE 838 Query: 785 IA----VMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQ----EDE---LVNRLAVLMDH 833 + + + LE+K ++ + QEK++ +E Q E+E L+ L+ D Sbjct: 839 KGNISNELSNTKQELEQKKQEIITITQEKEEKENELKEQVKKIEEEKSKLITELSNGSDG 898 Query: 834 DRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESES 893 + ++L + + E +E+QK + E+ + ++ L ++++ L E+ N+T E Sbjct: 899 ISKLNEELTQTKQEKEEIQKALEEEKEKLERIETELKEIKEAKQELEEEKNKTI---EEK 955 Query: 894 TKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKN 953 T Q +L + K+I E + Q K+E E++ E N+ E R ++ N+ +N Sbjct: 956 TNLQQELNEN----KKIVEE----LTQTKQEKEEINNELNSIKEEKKRIEEEKNQIINEN 1007 Query: 954 IEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINK 1013 E + ++E I +L ++EEL E + ++ ++ + +E +N+I Sbjct: 1008 KEIKEENIKSIEEKTQEINSLTTSIEELKGRLEESKGERIEIEKERDRVISE--LNDIKL 1065 Query: 1014 LN-ALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLL 1072 N + KQ +E + + + + S M++ +++ Q K + M E++ + QL Sbjct: 1066 QNEGMKKQVEEAHNRMTEMQKSFEGSENEMINSLNNQITQLNEKEKQMNEQVMALQTQLS 1125 Query: 1073 DSKQHNEELQILVREQDDQIKELKETK--LTFEMNIPKTEGMIISSTIEPMSDDANNVDX 1130 S + EE++ + E ++ ++ E K + E N E ++ +E + N++ Sbjct: 1126 QSNINLEEVKKDLIESQNKYTQINEEKDCVEQERNKINEEYKTVNEELEKNKKELNDLQT 1185 Query: 1131 XXXXXXXXXXXLKVQEEE---EFIQERSVLQEQSAKLNTELQECYTKIIQ----LETLNT 1183 K + +E++ L+EQ K+ E + T++ + LN Sbjct: 1186 KYDNEILELNKNKDELNSLINNLKEEKTNLEEQVKKMEEEKSKLITELSNGSDGVSKLNE 1245 Query: 1184 ELTGHDVVNQE---QINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWK 1240 ELT +E ++N +K + +++ E + +++ E++ +++ + E+ K Sbjct: 1246 ELTQTKQEKEEINNELNSIKEEKKRIEEEKNQIINENKEIKEEKEKIEEEKKELLKEIEK 1305 Query: 1241 QHLAQREADFQKTEHELRVQLSAFESKYEQLL----------DSVQSSTQEETNKIVTME 1290 + + Q + ++ ++ E K ++++ Q + Q+E N+I E Sbjct: 1306 EKEGNNQ--LQNEINTIQTRMKEIEEKNQEIICDNNKEIAKFKEEQENLQKELNQI--KE 1361 Query: 1291 QVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXX 1350 + + L L + + L L E+ + + E +R E+E K Sbjct: 1362 EKSKLITDLSNGNDGLSKLNEEIETINKEKEGIRKELESLKEENNKIQDELEQKNQELSK 1421 Query: 1351 DLRTENQSYKQMQE--QSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQ 1408 + + + I +NE+ Q+K +N +++ EL++ Sbjct: 1422 VKEEKEKLIHDLTNGNDGINQLNEDLNQIKNDKEELTEKNVQLQNEINKLKSENEELSNN 1481 Query: 1409 LELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHE 1468 L + + Q E + + R +LV+ K+IE+ + E EL Sbjct: 1482 LSFEKEGLKQVNEEV--------NAIKEERDELVKQIKKIEEEKRKVEEEL--------- 1524 Query: 1469 NANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALEN 1528 N N E ++ ++I K E+LN + E L + + EL +EE + + E + Sbjct: 1525 NFNGSEVNEQIAQINNEK--EQLNQECNE---LKQNLKELQSKIEE-IEQEKESNEIKKK 1578 Query: 1529 QEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELL 1581 +E++ L +EIT N ++ +I++ + ++ ++ +NT E L Sbjct: 1579 EELQ--ELQEEITEKDNDIKNLKEEIERIEKELQEKEEDMEQMSNNTEELEEL 1629 Score = 173 bits (422), Expect = 3e-41 Identities = 258/1282 (20%), Positives = 566/1282 (44%), Gaps = 119/1282 (9%) Query: 149 NTIKEKDNALSVLQVKMKI-METTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXX 207 N I E+ N L+ + +K +++ D K E ++I E KN+ Sbjct: 524 NQIVEEKNKLTEEKESIKQELDSIKADNSTKELEINKINEEKNQLQNDYDTVQQEKENIQ 583 Query: 208 XXXXEDTKQQMTKMQE-NFIAMEAEW-KDEKQRLLKDIESKDVRISSLEEANKLLEAARF 265 + ++ K +E N I E + +DEK +L+ DI + + ++ L E L+ + Sbjct: 584 KELNQIKIEKSQKEEELNKIKEEKQQVEDEKAKLITDIANGNDGLTKLNEVIDKLKDEKE 643 Query: 266 EISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELT 325 IS E +++ E + K+ I+ E ++ E+ S+ + + ++ Sbjct: 644 NISNELNQIKNERDNISNEFNKT--------KEEIKQKENETIQLNEEKSVLLNELNQIK 695 Query: 326 KKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSP 385 ++ + +E I+Q E EN++ + + + + + ++ N ++ K Sbjct: 696 EEKQKIEDEKAVIQQ---EKENEITKLNEDKTVIENELNQIKT--EKQEIENELNQTKDE 750 Query: 386 WSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGK 445 ++ E T+ + I+KL + L + +KE V++E + Sbjct: 751 KQKIEDEKSKLITELSNGNDGISKLN---EELTQTKQEKENVLNELNQIKNEFASFKEQN 807 Query: 446 DTLIAQLQLEH---QQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLI 502 +L+ E+ QQ +E + NE++K++E+ K +++E+ N K + Sbjct: 808 TQKENELKDENNKVQQELEQKN-----------NEVSKLEEE-KGNISNELS--NTKQEL 853 Query: 503 EKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKL-KQMQKTIDNFSKVSDSNKEIVRLT 561 E+ K ITQ +E + K +K K KL ++ D SK+ N+E+ + Sbjct: 854 EQKKQEIITITQEKEEKENELKEQVKKIEEEKSKLITELSNGSDGISKL---NEELTQTK 910 Query: 562 EELHHLSQKVAELEEEKGNLQLHLVDYDSGRM-IESDVYKKMIEMENLAETRLKAISLLE 620 +E + + + E +E+ ++ L + + +E + K + E NL + L E Sbjct: 911 QEKEEIQKALEEEKEKLERIETELKEIKEAKQELEEEKNKTIEEKTNLQQ------ELNE 964 Query: 621 SQKFDLVQELHILQQKYDEVEDKLADISQL------QSDQVCSEIKSVHLEEQIDALSAS 674 ++K +V+EL +Q+ +E+ ++L I + + +Q+ +E K + EE I ++ Sbjct: 965 NKK--IVEELTQTKQEKEEINNELNSIKEEKKRIEEEKNQIINENKEIK-EENIKSIEEK 1021 Query: 675 KKE---LALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEK 731 +E L IE LK E+ G ++E +++ ++++L + +N + ++E+ + + Sbjct: 1022 TQEINSLTTSIEELKGRLEESKGERIEIEKERDRVISELNDIKLQNEGMKKQVEE-AHNR 1080 Query: 732 ISELLAKINHEEQSKIQTQFGIDAKIQERDLYIEN----IESELSKYKSRICRLEESIAV 787 ++E+ E I + ++ E++ + ++++LS+ + +++ + Sbjct: 1081 MTEMQKSFEGSENEMINSLNNQITQLNEKEKQMNEQVMALQTQLSQSNINLEEVKKDLIE 1140 Query: 788 MEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHE 847 +++ + + D + QE+ K EY +EL L D + ++LE+ Sbjct: 1141 SQNKYTQINEEKDCVE---QERNKINEEYKTVNEELEKNKKELNDLQTKYDNEILELNKN 1197 Query: 848 NKELQKKNQILLEENQNLQISLSDMQQHYNALV-EKANRTD---LAESESTKYQTQLRDL 903 EL L EE NL+ + M++ + L+ E +N +D E T+ + + ++ Sbjct: 1198 KDELNSLINNLKEEKTNLEEQVKKMEEEKSKLITELSNGSDGVSKLNEELTQTKQEKEEI 1257 Query: 904 ESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQ 963 + L I E + I ++K +I + E + E +KK L ++ EK E QL+ + Sbjct: 1258 NNELNSIKEEKKR-IEEEKNQIINENKEIKEEKEKIEEEKKELLKEIEKEKEGNNQLQNE 1316 Query: 964 LQEYKNNIENLNMNVEELNKMNLELIDK------HVQKQQTQSPDYTEQYINEINKLNAL 1017 + + ++ + +E+ N + I K ++QK+ Q + + I +++ N Sbjct: 1317 INTIQTRMKEIEEKNQEIICDNNKEIAKFKEEQENLQKELNQIKEEKSKLITDLSNGNDG 1376 Query: 1018 LKQKDEEIIALNQKINNAQVSYMSMVSD---YESKLAQFTTKLENMEEEMQRVSKQLLDS 1074 L + +EEI +N++ + S+ + + +L Q +L ++EE +++ L + Sbjct: 1377 LSKLNEEIETINKEKEGIRKELESLKEENNKIQDELEQKNQELSKVKEEKEKLIHDLTNG 1436 Query: 1075 K----QHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDX 1130 Q NE+L ++ +++ E K +L E+N K+E +S+ + + V+ Sbjct: 1437 NDGINQLNEDLN-QIKNDKEELTE-KNVQLQNEINKLKSENEELSNNLSFEKEGLKQVNE 1494 Query: 1131 XXXXXXXXXXXL-----KVQEEEEFIQER-----SVLQEQSAKLNTELQECYTKIIQLET 1180 L K++EE+ ++E S + EQ A++N E ++ + +L+ Sbjct: 1495 EVNAIKEERDELVKQIKKIEEEKRKVEEELNFNGSEVNEQIAQINNEKEQLNQECNELKQ 1554 Query: 1181 LNTELTG--HDVVNQEQINQLKSK--LEQLN---TENDNLLSTVAELRSSISSAVDQRGF 1233 EL ++ +++ N++K K L++L TE DN + + E I + ++ Sbjct: 1555 NLKELQSKIEEIEQEKESNEIKKKEELQELQEEITEKDNDIKNLKEEIERIEKELQEKEE 1614 Query: 1234 EIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVT 1293 ++ ++ E + TE + +L E K ++ + + T+E+ +V +++V Sbjct: 1615 DMEQMSNNTEELEELKNKLTETQ---RLLEEEKKEKESISNEFEETKEQV--LVELQRVN 1669 Query: 1294 SLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLR 1353 + NK+ + ++ N +E+ + IN+ L+S+IE E +L+ Sbjct: 1670 NEMNKMNEIKQEDENEKEELQEHINK---LKSQIERENEQLKEVSKLKWELS-----ELK 1721 Query: 1354 TENQSYKQ--MQEQSILNINEE 1373 TEN+S KQ M ++S+L+ ++ Sbjct: 1722 TENESMKQMIMNKKSLLDNTDD 1743 Score = 172 bits (418), Expect = 8e-41 Identities = 220/1029 (21%), Positives = 454/1029 (44%), Gaps = 96/1029 (9%) Query: 215 KQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKL 274 K + +E E E KDE ++ +++E K+ +S LEE + IS E S Sbjct: 797 KNEFASFKEQNTQKENELKDENNKVQQELEQKNNEVSKLEEE-------KGNISNELSNT 849 Query: 275 AQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTE-IEEKGSLEIANMTELTKKIELLEH 333 QELEQ K+ E +E+ + IEE+ S I TEL+ + + Sbjct: 850 KQELEQKKQEIITITQE-----KEEKENELKEQVKKIEEEKSKLI---TELSNGSDGISK 901 Query: 334 LNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSET 393 LN ++ QT +E E KA+ +K + ++K +L E Sbjct: 902 LNEELTQTKQEKEEI-------QKALEEEKEKLERI------ETELKEIKEAKQELEEEK 948 Query: 394 LNQDTDKKIN-KNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQL 452 N+ ++K N + E+ + + +++ L + +KE + +E ++ K+ +I + Sbjct: 949 -NKTIEEKTNLQQELNENKKIVEELTQTKQEKEEINNELNSIKEEKKRIEEEKNQIINE- 1006 Query: 453 QLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQI 512 + ++ ++ + T+++N + E+LK L +E K + IE K + I Sbjct: 1007 ----NKEIKEENIKSIEEKTQEINSLTTSIEELKGRL-EESKG----ERIEIEKERDRVI 1057 Query: 513 TQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSK--VSDSNKEIVRLTEELHHLSQK 570 ++LND I N+ M K ++ +MQK+ + ++ N +I +L E+ ++++ Sbjct: 1058 SELND-IKLQNEGMKKQVEEAHNRMTEMQKSFEGSENEMINSLNNQITQLNEKEKQMNEQ 1116 Query: 571 VAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAIS----LLESQKFDL 626 V L+ + ++L + + + Y ++ E ++ E I+ + + Sbjct: 1117 VMALQTQLSQSNINLEEVKKDLIESQNKYTQINEEKDCVEQERNKINEEYKTVNEELEKN 1176 Query: 627 VQELHILQQKYD-EVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIEN- 684 +EL+ LQ KYD E+ + + +L S + + +LEEQ+ + K +L + N Sbjct: 1177 KKELNDLQTKYDNEILELNKNKDELNSLINNLKEEKTNLEEQVKKMEEEKSKLITELSNG 1236 Query: 685 -------------LKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEK 731 K +KE++ + ++ +K+ I + I EN ++ ++ EK+ EK Sbjct: 1237 SDGVSKLNEELTQTKQEKEEINNELNSIKEEKKRIEEEKNQIINENKEIKEEKEKIEEEK 1296 Query: 732 ISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDR 791 ELL +I E++ Q Q I+ IQ R IE E+ IC + IA ++ Sbjct: 1297 -KELLKEIEKEKEGNNQLQNEINT-IQTRMKEIEEKNQEI------ICDNNKEIAKFKEE 1348 Query: 792 RYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKEL 851 + +L+++ +Q+ +EK K ++ + D L + L + + K+ I E + L Sbjct: 1349 QENLQKELNQIK---EEKSKLITDLSNGNDGL----SKLNEEIETINKEKEGIRKELESL 1401 Query: 852 QKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRIT 911 +++N + +E + LS +++ L+ + ++ + Q+++ + L Sbjct: 1402 KEENNKIQDELEQKNQELSKVKEEKEKLIHDLTNGNDGINQLNEDLNQIKNDKEELTEKN 1461 Query: 912 HEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNI 971 + Q I + K E E+L + + E + + +N E+ E V Q++ +++E K + Sbjct: 1462 VQLQNEINKLKSENEELSNNLSFEKEGLKQVNEEVNAIKEERDELVKQIK-KIEEEKRKV 1520 Query: 972 ENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQK 1031 E EELN E V +Q Q + EQ E N+L LK+ +I + Q+ Sbjct: 1521 E------EELNFNGSE-----VNEQIAQINNEKEQLNQECNELKQNLKELQSKIEEIEQE 1569 Query: 1032 INNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQ 1091 + ++ + + + ++ + ++N++EE++R+ K+L + ++ E++ E ++ Sbjct: 1570 KESNEIKKKEELQELQEEITEKDNDIKNLKEEIERIEKELQEKEEDMEQMSNNTEELEEL 1629 Query: 1092 IKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFI 1151 +L ET+ E K E IS+ E + + ++++E+E Sbjct: 1630 KNKLTETQRLLEEE--KKEKESISNEFEETKEQV--LVELQRVNNEMNKMNEIKQEDE-- 1683 Query: 1152 QERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTEND 1211 E+ LQE KL ++++ ++ ++ L EL+ N+ + +K L+ +D Sbjct: 1684 NEKEELQEHINKLKSQIERENEQLKEVSKLKWELSELKTENESMKQMIMNKKSLLDNTDD 1743 Query: 1212 NLLSTVAEL 1220 +L ++ L Sbjct: 1744 FILMSLEYL 1752 Score = 132 bits (319), Expect = 8e-29 Identities = 188/858 (21%), Positives = 397/858 (46%), Gaps = 84/858 (9%) Query: 147 LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXX 206 L+ T +EK+ L+ + + +E +L+E K ++ E KNK Sbjct: 906 LTQTKQEKEEIQKALEEEKEKLERIETELKEIKEAKQELEEEKNKTIEEKTNLQQELNEN 965 Query: 207 XXXXXE--DTKQQMTKMQENFIAMEAEWK---DEKQRLL-KDIESKDVRISSLEEANKLL 260 E TKQ+ ++ +++ E K +EK +++ ++ E K+ I S+EE + + Sbjct: 966 KKIVEELTQTKQEKEEINNELNSIKEEKKRIEEEKNQIINENKEIKEENIKSIEEKTQEI 1025 Query: 261 EAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIAN 320 + I +L + + L ++ +K ++EE + Sbjct: 1026 NSLTTSIEELKGRLEESKGERIEIEKERDRVISELNDIKLQNEGMKK-QVEEAHN----R 1080 Query: 321 MTELTKKI-----ELLEHLNCQIRQTN---KELENKLATMGTE-SKAVSSPSKKGSPLIS 371 MTE+ K E++ LN QI Q N K++ ++ + T+ S++ + + LI Sbjct: 1081 MTEMQKSFEGSENEMINSLNNQITQLNEKEKQMNEQVMALQTQLSQSNINLEEVKKDLIE 1140 Query: 372 RKSGRNTASKMKSPWSQ----LSSE--TLNQDTDKKINKNEI----AKLEMVIQSLNKDL 421 ++ ++ K Q ++ E T+N++ +K NK E+ K + I LNK+ Sbjct: 1141 SQNKYTQINEEKDCVEQERNKINEEYKTVNEELEK--NKKELNDLQTKYDNEILELNKNK 1198 Query: 422 VDKEYVIS----EKDTXXXXXXXXXXGKDTLIAQLQLEHQQHME-GPSLIHVGTNTEDV- 475 + +I+ EK K LI +L + L E++ Sbjct: 1199 DELNSLINNLKEEKTNLEEQVKKMEEEKSKLITELSNGSDGVSKLNEELTQTKQEKEEIN 1258 Query: 476 NEIAKVQEQLK--QELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANK--NMIKVKS 531 NE+ ++E+ K +E ++I + N K++ E+ + EE+ +L EI+ + N ++ + Sbjct: 1259 NELNSIKEEKKRIEEEKNQIINEN-KEIKEEKEKIEEEKKELLKEIEKEKEGNNQLQNEI 1317 Query: 532 NH-KLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDS 590 N + ++K++++ N + D+NKEI + EE +L +++ +++EEK L L + + Sbjct: 1318 NTIQTRMKEIEE--KNQEIICDNNKEIAKFKEEQENLQKELNQIKEEKSKLITDLSNGND 1375 Query: 591 G-----RMIES-DVYKKMI--EMENLAETRLKAISLLE--SQKFDLVQE-----LHILQQ 635 G IE+ + K+ I E+E+L E K LE +Q+ V+E +H L Sbjct: 1376 GLSKLNEEIETINKEKEGIRKELESLKEENNKIQDELEQKNQELSKVKEEKEKLIHDLTN 1435 Query: 636 KYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKE---QL 692 D + D++Q+++D+ K+V L+ +I+ L + +EL+ NL +KE Q+ Sbjct: 1436 GNDGINQLNEDLNQIKNDKEELTEKNVQLQNEINKLKSENEELS---NNLSFEKEGLKQV 1492 Query: 693 YGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFG 752 + ++ ++++++ +++ +E + ++L + +++E +A+IN+E++ Q Sbjct: 1493 NEEVNAIKEERDELVKQIKKIEEEKRKVEEEL-NFNGSEVNEQIAQINNEKEQLNQECNE 1551 Query: 753 IDAKIQERDLYIENIESELS----KYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQE 808 + ++E IE IE E K K + L+E I ++ +L+ + +++ LQE Sbjct: 1552 LKQNLKELQSKIEEIEQEKESNEIKKKEELQELQEEITEKDNDIKNLKEEIERIEKELQE 1611 Query: 809 KQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQIS 868 K++ + + +EL L + R++E++ E E + E ++ + +L E Q + Sbjct: 1612 KEEDMEQMSNNTEELEELKNKLTETQRLLEEEKKEKESISNEFEETKEQVLVELQRVNNE 1671 Query: 869 LSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDL 928 ++ M + +++ + E+E + Q + L+S ++R +E + + K E+ +L Sbjct: 1672 MNKMNE-----IKQED-----ENEKEELQEHINKLKSQIER-ENEQLKEVSKLKWELSEL 1720 Query: 929 EIEFNTQIESAIRDKKVL 946 + E N ++ I +KK L Sbjct: 1721 KTE-NESMKQMIMNKKSL 1737 Score = 99 bits (238), Expect = 5e-19 Identities = 168/855 (19%), Positives = 359/855 (41%), Gaps = 90/855 (10%) Query: 804 SYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQ 863 S+ + + ++ E + LA + V +IE ENK LQ +N+ L++ Sbjct: 142 SFSKRNSTENTGHSSSEHSATSSLASETTAEEVNRSVNAQIEEENKRLQNENE-ELKKKC 200 Query: 864 NLQISL------SDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTL 917 + Q SL S+M+ + + + DL + + + + L L +I +E +++ Sbjct: 201 DAQDSLLKTKMKSEMEAKKKVEILENEKKDLIDKMANE-NDGMSKLNEELTQIKNEKESI 259 Query: 918 ---IVQKKKEIEDLEIEFNTQIESAIRDKK-VLNEKYEKNIEYVTQLEAQLQEYKNNIEN 973 ++Q K+E E + E TQ+++ K+ LN+ + E + + +E + + Sbjct: 260 NNELIQTKQEKESINNEL-TQLKTDNDQKENELNQVRHEKDEVIEKFNTSKEENEKIMNE 318 Query: 974 LNMNVEELNKMNLELIDKHVQKQQTQSPDYTE--QYINEINKLNALLKQKDEEIIALNQK 1031 L+ +E + EL ++ + ++ +S TE + I+KLN L Q +E +N + Sbjct: 319 LSQLKQEKEEKENELKEQVKKMEEEKSKLITELSNGSDGISKLNEELTQTKQEKEEINNE 378 Query: 1032 INNAQVSYMSMVSDYE---SKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQ 1088 +N+ + + + ++ + + E +EEE + + K++ K+ N +LQ + Sbjct: 379 LNSIKEEKKRIEEEKNQIINENKEIKEEKEKIEEEKKELLKEIEKEKEGNNQLQNEINTI 438 Query: 1089 DDQIKELKE-------------TKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXX 1135 ++KE++E K E + E I + ++ N + Sbjct: 439 QTRMKEIEEKNQEIICDNNKEIAKFKEEQENLQKELNQIKEEKQKTENEKNELVDVKTQK 498 Query: 1136 XXXXXXLKVQEEEEF-------------IQERSVLQEQSAKLNTELQ----ECYTKIIQL 1178 LK ++E+ F ++E++ L E+ + EL + TK +++ Sbjct: 499 ENELNKLKEEKEQIFNEKTTIENSLNQIVEEKNKLTEEKESIKQELDSIKADNSTKELEI 558 Query: 1179 ETLNTE----LTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFE 1234 +N E +D V QE+ N ++ +L Q+ E + +++ D++ Sbjct: 559 NKINEEKNQLQNDYDTVQQEKEN-IQKELNQIKIEKSQKEEELNKIKEEKQQVEDEKAKL 617 Query: 1235 IAEL--WKQHLAQREADFQKTEHE---LRVQLSAFESKYEQLLDSVQSSTQE----ETNK 1285 I ++ L + K + E + +L+ +++ + + + + +E E Sbjct: 618 ITDIANGNDGLTKLNEVIDKLKDEKENISNELNQIKNERDNISNEFNKTKEEIKQKENET 677 Query: 1286 IVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXX 1345 I E+ + L N+L +E + ++++ A + + E +++ ++K Sbjct: 678 IQLNEEKSVLLNELNQIKEEKQKIEDEKAVIQQEKENEITKLNEDKTVIENELNQIKTEK 737 Query: 1346 XXXXXDL-RTENQSYKQMQEQSIL-----NINEENAQLKKSSXXXXXXXXXXXXRVNDAE 1399 +L +T+++ K E+S L N N+ ++L + +N + Sbjct: 738 QEIENELNQTKDEKQKIEDEKSKLITELSNGNDGISKLNEELTQTKQEKENVLNELNQIK 797 Query: 1400 AKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYE---KE 1456 + Q K++E+ + ++ L Q+N+E + ++ + + E K+ Sbjct: 798 NEFASFKEQNTQKENELKDENNKVQQELEQKNNEVSKLEEEKGNISNELSNTKQELEQKK 857 Query: 1457 SELAILRLKMHENANHYETMQKESEIERVKLIEELN------VKITESVSLNKQ-VAELN 1509 E+ + + E N + K+ E E+ KLI EL+ K+ E ++ KQ E+ Sbjct: 858 QEIITITQEKEEKENELKEQVKKIEEEKSKLITELSNGSDGISKLNEELTQTKQEKEEIQ 917 Query: 1510 KALEEEVAKTNEMQTALE-----NQEIEIVTLN--DEITNLQNMVRASSSKIQKHVSFAS 1562 KALEEE K ++T L+ QE+E +E TNLQ + + +K V + Sbjct: 918 KALEEEKEKLERIETELKEIKEAKQELEEEKNKTIEEKTNLQQELNEN----KKIVEELT 973 Query: 1563 DTKQGRDEQLDNTMN 1577 TKQ + E+++N +N Sbjct: 974 QTKQEK-EEINNELN 987 Score = 72.9 bits (171), Expect = 7e-11 Identities = 113/543 (20%), Positives = 235/543 (43%), Gaps = 35/543 (6%) Query: 218 MTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQE 277 ++K+ E + E K+E L I+ + RI EE N+++ + EI E K+ +E Sbjct: 1240 VSKLNEELTQTKQE-KEEINNELNSIKEEKKRIE--EEKNQIINENK-EIKEEKEKIEEE 1295 Query: 278 LEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIA-NMTELTKKIELLEHLNC 336 ++ L + I EIEEK I N E+ K E E+L Sbjct: 1296 KKELLKEIEKEKEGNNQLQNE-INTIQTRMKEIEEKNQEIICDNNKEIAKFKEEQENLQK 1354 Query: 337 QIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSG-RNTASKMKSPWSQLSSETLN 395 ++ Q +E + + + +S +++ + K G R +K +++ E Sbjct: 1355 ELNQIKEEKSKLITDLSNGNDGLSKLNEEIETINKEKEGIRKELESLKEENNKIQDELEQ 1414 Query: 396 QDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLE 455 ++ + K E KL + + N + +++ I +L+ E Sbjct: 1415 KNQELSKVKEEKEKLIHDLTNGNDGINQLNEDLNQIKNDKEELTEKNVQLQNEINKLKSE 1474 Query: 456 HQQHMEGPSLIHVGTN--TEDVNEIAKVQEQLKQELN--DEIKDVNVKDLIEKLKSAEEQ 511 +++ S G E+VN I + +++L +++ +E K ++L EQ Sbjct: 1475 NEELSNNLSFEKEGLKQVNEEVNAIKEERDELVKQIKKIEEEKRKVEEELNFNGSEVNEQ 1534 Query: 512 ITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNK-----EIVRLTEELHH 566 I Q+N+E + N+ ++K N LK++Q I+ + +SN+ E+ L EE+ Sbjct: 1535 IAQINNEKEQLNQECNELKQN----LKELQSKIEEIEQEKESNEIKKKEELQELQEEITE 1590 Query: 567 LSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMEN-LAET-RLKAISLLE---- 620 + L+EE ++ L + + S+ +++ E++N L ET RL E Sbjct: 1591 KDNDIKNLKEEIERIEKELQEKEEDMEQMSNNTEELEELKNKLTETQRLLEEEKKEKESI 1650 Query: 621 SQKFDLVQELHILQ-QKYDEVEDKLADISQLQSDQVCSEIKSVH-LEEQIDALSASKKEL 678 S +F+ +E +++ Q+ + +K+ +I Q ++ + ++ L+ QI+ + KE+ Sbjct: 1651 SNEFEETKEQVLVELQRVNNEMNKMNEIKQEDENEKEELQEHINKLKSQIERENEQLKEV 1710 Query: 679 ALV---IENLKLDKEQLYGTIKD----LENDKEDIMNKLQNYIQENMDLTDKLEKMSAEK 731 + + + LK + E + I + L+N + I+ L+ +++ +T K+E + E Sbjct: 1711 SKLKWELSELKTENESMKQMIMNKKSLLDNTDDFILMSLEYLYFDSVWVTLKMELLDEED 1770 Query: 732 ISE 734 + + Sbjct: 1771 LDD 1773 >UniRef50_A2FD36 Cluster: Viral A-type inclusion protein, putative; n=1; Trichomonas vaginalis G3|Rep: Viral A-type inclusion protein, putative - Trichomonas vaginalis G3 Length = 3977 Score = 210 bits (514), Expect = 2e-52 Identities = 304/1481 (20%), Positives = 622/1481 (41%), Gaps = 121/1481 (8%) Query: 147 LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXX 206 L NTI++ +A L K ++ +++LQ+ EK+Q+ +K T Sbjct: 245 LENTIEQLKSANKELSDKNVEIQAKLINLQK---EKEQLTSTNDKLLTETENLKKEIDEL 301 Query: 207 XXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDI--ESKDV--RISSLEEANKLLEA 262 E + + Q +++ E K +++++D+ E D+ +I LE NK + + Sbjct: 302 NNANKELNVKSINLQQ----SLDNE-KQNNKKMIQDLNKEKTDLISKIEKLEMDNKEMNS 356 Query: 263 ARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMT 322 ++ ++ L + + ++ IE +E TE+ + + Sbjct: 357 KLNNVNTSYNDLDAKNQNNQTKVNNL--------EKIIEKLIKENTELANNNKNNNSKID 408 Query: 323 ELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKM 382 EL + + L + + N+ L+ K+ + E + +K L S G + Sbjct: 409 ELQNQNKDLISASNDMNTKNQSLQTKIDQLNKEKTELE---EKNKVLKSNLEGLKSDLLS 465 Query: 383 KSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXX 442 K+ S +E L + D+ N+N++ + Q+ D ++KE + D Sbjct: 466 KNQESTKKNENLQKIIDQLQNENKLLSSNLENQTKLNDDLNKE----KSDLQSKIEELEK 521 Query: 443 XGKDTLIAQLQLEHQQHMEGPSLIH-VGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDL 501 KD L + L+ H+ E + I+ + N +++ + Q +L +LN E D Sbjct: 522 NNKD-LTSNLENNHKTIEELSNKINDLQNNNKELTSNLEDQNKLNDDLNKEKAD------ 574 Query: 502 IEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLT 561 L+S E+++ N+E++++NKN K N + K+ + +K ID K + +E +++ Sbjct: 575 ---LQSKIEELSTKNEELESSNKNE---KENLQNKVDEFEKIIDQLRKEKEVLEENEKVS 628 Query: 562 EELHHLSQKVAE-LEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLE 620 + KV E L EK +LQ + + D+ + E+ N ++ L SL Sbjct: 629 KTNIDDDYKVIEELNNEKSDLQSKIDQLEKNN---KDLTTNL-ELSNKEKSDL---SLEN 681 Query: 621 SQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELAL 680 K + EL L K + +KL QLQ ++ E + L+++ + LS+ +L Sbjct: 682 ENKRKEIDELKSLNNKTNNDIEKL----QLQIQEL--EKSNEQLQKEKEVLSSENNQLKS 735 Query: 681 VIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKIN 740 +EN +KE I L +K D+ +K++ N +L LE + K++++L N Sbjct: 736 NVENS--EKE-----IGILNKEKADLQSKVEELDNNNKELASNLENQN--KLNKVLNNEN 786 Query: 741 HEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKAD 800 + QSKI+ + K QE + +E ++RI LE+ I ++ +LE +++ Sbjct: 787 SDLQSKIEE---LTTKNQELESSNIETNNEKENLQARINELEKIIDELQKENENLETESN 843 Query: 801 QLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLE 860 L + LQ +K ++ +++L +++ L +++ + +I NK+LQ KN L Sbjct: 844 HLRTDLQNNEKTIADLNKDKNDLTSKIGELEKNNKEFTTLIDKINASNKDLQTKNDELQS 903 Query: 861 ENQNLQISLSDMQQHYNALVEKAN--RTDLAESEST--KYQTQLRDLESNLKRITHEHQT 916 + L+ L + + + L+ K +T + + + T + +DL++ ++ + E+ Sbjct: 904 KVDLLEKILDQLNKDKSDLITKLEELQTSIDQMKQTNENLNKENKDLQNKIEELLEEND- 962 Query: 917 LIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNM 976 + E E E I+ +K L K+E++ + + + E E L Sbjct: 963 ---KANNENESKNKELQQIIDQLAEEKLSLQNKFEESEKNAKDNQKIIDELIAENEKLTS 1019 Query: 977 NVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQ 1036 + E K+ LE + +++ + E+ EI K LK ++ I+ + NN Sbjct: 1020 SNNE-EKVELESLKNSLEETKQNDDKLVEELSKEIEK----LKNENNSILENSDSKNNEN 1074 Query: 1037 VSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIK--- 1093 + + +S L KL E+ ++V + L++ + +E + +Q +++K Sbjct: 1075 QQIIDQLKKEKSDLMNQVDKLTKKNEDQEKVIQDLINDQNQKDEENKQMNDQSNELKSQI 1134 Query: 1094 ------------ELKETK-----LTFEMNIPKTEGMIISSTIEPMSDDANN-VDXXXXXX 1135 +L++ K L E I ++E + +E + N +D Sbjct: 1135 EKISIENETLKSDLQKNKESNGELMKEREISQSELEELKKLLEETKQNDNKLIDKLRNEN 1194 Query: 1136 XXXXXXLKVQEE------EEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHD 1189 L + + ++F +E S L Q +LN E I LE + LT + Sbjct: 1195 QSLNNQLDMNNKDHQQIIDQFTKEESDLMSQIEELNALNNELNVNIQNLEQDKSNLTKQN 1254 Query: 1190 VVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWK--QHLAQRE 1247 +N+ K + + L+ EN+ L S L+S + ++ + +L K + L + Sbjct: 1255 EELNALLNETKLQNQNLSNENETLRSNNERLQSELKQNEEKSKSDFDQLTKDLETLKSEQ 1314 Query: 1248 ADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLR 1307 ++ K EL+ + + E +L + T T++ +EQ+ ++ L + Sbjct: 1315 SNKDKMIDELQNKTNDLEESIGKLNEEKAKITDSLTDRDQKIEQLNKEKSDLISDINNFE 1374 Query: 1308 NLQEKYADVINQIEILRSEI--EDEKVAFXXXXXXXXXXXXXXXXDLR-TENQSYKQMQE 1364 Q++ D I+ + ++ E+EK+ + + E +S Q Sbjct: 1375 ASQKELNDKIDSLNSANKDLNQENEKLKSQISSLENENSSLQSANNSKDKEIKSINQQLS 1434 Query: 1365 QSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYT 1424 ++I + + +Q + + + +E ++ EL ++LE +EI Q + Sbjct: 1435 ETISSFDNYKSQHESEAEALSNKLNNLEANKDKSEKELEELRNELEKLQNEI-QIREQRE 1493 Query: 1425 ITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIER 1484 L+ +N+E N+ +++ + + + E IL+ + EN +Y+ + E E Sbjct: 1494 KELSNQNEELMNILEKMKSELNDVNMNNEQLDQEKEILKKSLEENQQNYDQLIDELSKEI 1553 Query: 1485 VKLIEELNVKITESVSLNKQVAEL-----NKALEEEVAKT--NEMQTALENQEIEIVTLN 1537 L ++L K +S S ++ EL N + E E K+ NE++ L++ +N Sbjct: 1554 EVLKKQLLTKDADSNSSKHEIDELQSKIQNLSSENENLKSTNNELKQNLDDILKNNEQIN 1613 Query: 1538 DEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNK 1578 E+T + + S+I+ + KQ DEQL + ++K Sbjct: 1614 SELTETKQTNKDLLSQIESLKKVLEENKQ-NDEQLVDELSK 1653 Score = 203 bits (495), Expect = 4e-50 Identities = 302/1519 (19%), Positives = 645/1519 (42%), Gaps = 138/1519 (9%) Query: 93 SLANTLK-QKEILMEKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTI 151 SL+N LK Q E+L ++ + K +R+ I + ++ +L + Sbjct: 1938 SLSNKLKPQIEVLSKENESLKSEIQRNHENIEKLQQKLDESQQTNENSS-NEIDNLKKLL 1996 Query: 152 KEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXX 211 +E +N + L + ++ I D + I E ++ +A N + Sbjct: 1997 EEANNNHNQLMNDFENLKHEISDKDKMIQELEKRNDANNNQNSDLSAKLKESEAKISELD 2056 Query: 212 EDTKQQMTKMQENFIAMEAEWKDEKQRL---LKDIESKDVRIS-----SLEEANKLLEAA 263 ++ ++ E + M E K+ Q + +++I +++V + S E +NKL Sbjct: 2057 SQIEKYKQEL-EKLMKMNNELKETVQEMENQIQNISNENVNLKTEVDKSKENSNKLQNDL 2115 Query: 264 RFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTE 323 E + L ++E + + + ++ +E +L+ + Sbjct: 2116 N-EAKQNNENLLSQIESLKKLLEENDANFEKMKSELNDAKMNKEHSDQENETLKKSLEEN 2174 Query: 324 LTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSG-RNTASKM 382 +L++ L+ +I + K+L K + + K L S ++T +++ Sbjct: 2175 QQNYDQLVDELSKEIEELKKQLLTKAEESNSSKHEIDELQSKIQNLSSENENLKSTNNEL 2234 Query: 383 KSPWSQL--SSETLNQDTD--KKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXX 438 K + ++E +N + K+ NK+ ++++E + + L ++ + E ++ E Sbjct: 2235 KQNLDDILKNNEQINSELTETKQTNKDLLSQIESLKKVLEENKQNDEQLVDELSKAPDEM 2294 Query: 439 XXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELN------DE 492 KD I +L E ++ + H + + + E+ K + +L +++ D+ Sbjct: 2295 KHEQQKKDNRIDELTKE-KETLYNTLNSHDKDHQQIIEEMNKEKSELGSQIHEYESELDK 2353 Query: 493 IKDVNVKDLIE---KLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNF-S 548 +K +N K+L E KL + ++ + N+++ N ++I +++ + + + ID S Sbjct: 2354 LKSLN-KELNENNTKLNQDKSELIKQNEDLTRNNNDLINAQNDKDRIINENKAKIDELPS 2412 Query: 549 KVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEM--- 605 ++D + L+ E + L Q+V +L+ E G+ + + + IES+ KK +E Sbjct: 2413 LLNDLQSHLQNLSNENNSLKQEVEKLQTELGDSKQN----EEKSKIESEQMKKSLEETKQ 2468 Query: 606 --ENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVH 663 E L + K I L++++ + + + L K + + L D + + +Q+ ++ Sbjct: 2469 NDEQLVDELTKEIEKLKNEQLNKDRTIQNLTNKNESINKNL-DSNNKEYEQIIDQLNQDL 2527 Query: 664 LEEQ--IDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLT 721 E + ++ EL L+ + L+ D E L DL N E++ K +N I N+ T Sbjct: 2528 SESKSKLNDYETKMNELNLLNKELQKDNETLKENQSDLINQIEELSKKNENLI--NLQGT 2585 Query: 722 DKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRL 781 + + +++ +L+ K+N E+ IQ E + +N K +S L Sbjct: 2586 NSNLVLKNDELQQLIDKLNKEKSDLIQ----------ENERLTKNNGESNEKLQS----L 2631 Query: 782 EESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQL 841 ++ I +++ +++ Q+ L K+K +++ E N+L VL + L Sbjct: 2632 DQMIETVKNNSSEKDKENHQIIDQLN-KEKLDLSSKLKDYE--NQLDVL-------KSSL 2681 Query: 842 LEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLR 901 E+ +NKELQ N IL +EN+ L +S ++ N+ ++ N E E +L+ Sbjct: 2682 KELNDKNKELQNGNDILKQENETLTPKISSLESE-NSSLKSTNEIKDKEIE------ELK 2734 Query: 902 DLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLE 961 S + ++ +H++ + ++K+ E E Q+E + ++ ++ ++ +L Sbjct: 2735 QKLSEISQLNSQHESDLDSRRKQFEKELEELRNQLEKLQNEIQIREQRGKELSNQNEELM 2794 Query: 962 AQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQK 1021 L++ K+ + + MN E ++ N E + K +++ Q ++ EI +L L K Sbjct: 2795 NNLEKMKSELNDAKMNKEHSDQEN-ETLKKSLEENQQNYDQLVDELSKEIEELKKQLLTK 2853 Query: 1022 DEEIIALNQKINNAQVSYMSMVSDYES----------KLAQFTTKLENMEEEMQRVSKQL 1071 EE + +I+ Q ++ S+ E+ ++ L+N ++ ++ ++K++ Sbjct: 2854 AEESNSSKHEIDELQSKIQNLSSENENLKSTNNELKQQIESLKNDLQNKDQIVEELTKEI 2913 Query: 1072 LDS-KQHNEELQILVREQDDQIKELKE-TKLTFEM--NIPKTEGMIISSTI--EPMSDDA 1125 S KQ +E ++L ++Q D +K++++ TK EM E +I I E ++ + Sbjct: 2914 DSSNKQSHENNELLNQKQLDLMKQIEDLTKKQGEMLKQNQNQENIINDLKIKNEELTKEG 2973 Query: 1126 NNVDXXXXXXXXXXXXLK--VQE-EEEFIQERSVLQEQSA-------KLNTELQECYTKI 1175 NN D K +Q E + +S LQ KLN+ Q + Sbjct: 2974 NNKDKVINELNKSLNDFKSLIQNLSNENEKLKSALQNSQGNNADLQQKLNSTQQNDQNLL 3033 Query: 1176 IQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEI 1235 Q+E L L N++ + L ++++ EN N + +LR + ++ + +I Sbjct: 3034 NQIELLKKSLQ----ENKQNEDNLVNEIQNQKIENQNKDQIIEDLRKK-NEELNLKQQQI 3088 Query: 1236 AELW---KQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQ- 1291 + + K L + + +EL E + L++ + ++ N+I+ +Q Sbjct: 3089 QDQFNKEKSGLISKLQGLNLSGNELLSNNEKLEQEQSDLMNQINDLRKK--NEILNQQQA 3146 Query: 1292 -----VTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXX 1346 + Q K+Q+ EE LQ K + +N E +++I+ K Sbjct: 3147 NNNQIIKECQEKIQNYEESNNELQRKLNEAMNNNENAKNQIDQLK----KLLEETKQNDD 3202 Query: 1347 XXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELT 1406 +L E + K Q+ NIN+ +A K S + ND +K + Sbjct: 3203 KLVEELTKEIEKLKNEQQSKDQNINDLSALNKDKS---------SLIQQNDDLSKKTQEF 3253 Query: 1407 HQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKM 1466 + + +++ + + +L Q+N E N E ++ I+ LT +K S+LA Sbjct: 3254 YNSQQNQAQMIEDLKKQNESL-QKNLEINN-----NETQQNIDQLTKDK-SDLASKLHDY 3306 Query: 1467 HENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTAL 1526 N ++ KE E+ +IE+ N + ++ + +N + N L++ + + N+ +T L Sbjct: 3307 EAKINDLNSLIKELN-EKNAIIEKKNYEFSQQLEVNNDLISKNNQLQQTIDQLNKDKTVL 3365 Query: 1527 ENQEIEIVTLNDEITNLQN 1545 Q ++ N+EITN N Sbjct: 3366 SKQIQDLANKNNEITNQLN 3384 Score = 202 bits (492), Expect = 8e-50 Identities = 296/1390 (21%), Positives = 596/1390 (42%), Gaps = 121/1390 (8%) Query: 231 EWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXX 290 E EK L I + + L+ NK L +++ + S+L ++ E Sbjct: 2332 EMNKEKSELGSQIHEYESELDKLKSLNKELNENNTKLNQDKSELIKQNEDLTRNNNDLIN 2391 Query: 291 XXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKL- 349 K I E K +I+E SL + +L ++ L + N ++Q ++L+ +L Sbjct: 2392 AQND--KDRIIN--ENKAKIDELPSL----LNDLQSHLQNLSNENNSLKQEVEKLQTELG 2443 Query: 350 -ATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIA 408 + E + S K S ++++ ++ +L +E LN+D + +N Sbjct: 2444 DSKQNEEKSKIESEQMKKSLEETKQNDEQLVDELTKEIEKLKNEQLNKD---RTIQNLTN 2500 Query: 409 KLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHV 468 K E + ++L+ + + E +I + + +T + +L L +++ + + Sbjct: 2501 KNESINKNLDSNNKEYEQIIDQLNQDLSESKSKLNDYETKMNELNLLNKELQKDNETLKE 2560 Query: 469 GTNT--EDVNEIAKVQEQL--KQELNDEI--KDVNVKDLIEKLKSAEEQITQLNDEIDAA 522 + + E++K E L Q N + K+ ++ LI+KL + + Q N+ + Sbjct: 2561 NQSDLINQIEELSKKNENLINLQGTNSNLVLKNDELQQLIDKLNKEKSDLIQENERLTKN 2620 Query: 523 NKNMIKVKSNHKLK-LKQMQKTIDNFSKVSDS-NKEIV-RLTEELHHLSQKVAELEEEKG 579 N +SN KL+ L QM +T+ N S D N +I+ +L +E LS K+ + E + Sbjct: 2621 NG-----ESNEKLQSLDQMIETVKNNSSEKDKENHQIIDQLNKEKLDLSSKLKDYENQLD 2675 Query: 580 NLQLHLVDY-DSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYD 638 L+ L + D + +++ +++ EN ET IS LES+ L I ++ + Sbjct: 2676 VLKSSLKELNDKNKELQNG--NDILKQEN--ETLTPKISSLESENSSLKSTNEIKDKEIE 2731 Query: 639 EVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKD 698 E++ KL++ISQL S L+ + +EL +E L+ + + K+ Sbjct: 2732 ELKQKLSEISQLNSQHESD------LDSRRKQFEKELEELRNQLEKLQNEIQIREQRGKE 2785 Query: 699 LENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAK-INHEEQSKIQTQFGIDAKI 757 L N E++MN L+ E D K+ K +++ +E L K + +Q+ Q + +I Sbjct: 2786 LSNQNEELMNNLEKMKSELNDA--KMNKEHSDQENETLKKSLEENQQNYDQLVDELSKEI 2843 Query: 758 QE--RDLYIENIESELSKYK-----SRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQ 810 +E + L + ES SK++ S+I L ++ L+++ + L + LQ K Sbjct: 2844 EELKKQLLTKAEESNSSKHEIDELQSKIQNLSSENENLKSTNNELKQQIESLKNDLQNKD 2903 Query: 811 KAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLS 870 + E T +E + N+ + +++ ++ ++ L++ + ++L KK +L++NQN + ++ Sbjct: 2904 QIVEELT-KEIDSSNKQS--HENNELLNQKQLDLMKQIEDLTKKQGEMLKQNQNQENIIN 2960 Query: 871 DMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEI 930 D++ L ++ N D +E K + L NL + ++ + + DL+ Sbjct: 2961 DLKIKNEELTKEGNNKDKVINELNKSLNDFKSLIQNLSNENEKLKSALQNSQGNNADLQQ 3020 Query: 931 EFNT---QIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLE 987 + N+ ++ + ++L + ++N + L ++Q K +N + +E+L K N E Sbjct: 3021 KLNSTQQNDQNLLNQIELLKKSLQENKQNEDNLVNEIQNQKIENQNKDQIIEDLRKKNEE 3080 Query: 988 LIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYE 1047 L ++++QQ Q + ++ I+KL L E+++ N+K+ Q M+ ++D Sbjct: 3081 L---NLKQQQIQD-QFNKEKSGLISKLQGL-NLSGNELLSNNEKLEQEQSDLMNQINDLR 3135 Query: 1048 SKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVRE----------QDDQIKEL-K 1096 K + N + ++ +++ + ++ N ELQ + E Q DQ+K+L + Sbjct: 3136 KKNEILNQQQANNNQIIKECQEKIQNYEESNNELQRKLNEAMNNNENAKNQIDQLKKLLE 3195 Query: 1097 ETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSV 1156 ETK + + + I E S D N D +++ IQ+ Sbjct: 3196 ETKQNDDKLVEELTKEIEKLKNEQQSKDQNINDLSALN----------KDKSSLIQQNDD 3245 Query: 1157 LQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLST 1216 L +++ + Q I L+ N L + +N N+ + ++QL + +L S Sbjct: 3246 LSKKTQEFYNSQQNQAQMIEDLKKQNESLQKNLEINN---NETQQNIDQLTKDKSDLASK 3302 Query: 1217 VAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQ 1276 + + + I+ ++ L K+ L ++ A +K +E QL + Q Sbjct: 3303 LHDYEAKIN--------DLNSLIKE-LNEKNAIIEKKNYEFSQQLEVNNDLISKNNQLQQ 3353 Query: 1277 SSTQEETNKIVTMEQVTSLQNKLQDKEEHLRN-----LQEKY-ADVINQ-IEILRSEIED 1329 + Q +K V +Q+ L NK + L N L+ K +D +NQ + L E+ Sbjct: 3354 TIDQLNKDKTVLSKQIQDLANKNNEITNQLNNKDKIILESKQKSDELNQSLSNLMKELHT 3413 Query: 1330 EKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXX 1389 K A +L+ + + K++ + + N N+ L K Sbjct: 3414 LK-ANNDDLNSQISQSKQNEENLQLQIEKQKKLLQDTKQNDNKLVDDLSKEVETLTSEKL 3472 Query: 1390 XXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIE 1449 + AK + QL+ K+ EI ++ ++ + E +Q+ EK + Sbjct: 3473 KNEEIIKQNNAKYSGILKQLQQKNEEINKEKEQF-------KHDLEGEKQK---NEKLVN 3522 Query: 1450 DLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVS-LNKQVAEL 1508 DL K+ +L+ + +E HY K++ + I N + E++ L KQ+ L Sbjct: 3523 DLNQTKD-KLS----QENEKLKHYLVAFKQNNEQ----ITADNKQKDENIQQLMKQINSL 3573 Query: 1509 NKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGR 1568 L+E+ ++ EN + I LN E +L + + S K + +S ++ Q Sbjct: 3574 KSQLQEDEKLKSQFAKMKENYDSLINKLNQENKSLTHSLN-ESLKHNEELSKNNEKLQQN 3632 Query: 1569 DEQLDNTMNK 1578 +E L N +N+ Sbjct: 3633 NELLSNKLNQ 3642 Score = 201 bits (490), Expect = 1e-49 Identities = 299/1471 (20%), Positives = 630/1471 (42%), Gaps = 117/1471 (7%) Query: 150 TIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXX 209 TI+E N ++ LQ K + + + D Q K+N D + + K + Sbjct: 536 TIEELSNKINDLQNNNKELTSNLED-QNKLN--DDLNKEKADLQSKIEELSTKNEELESS 592 Query: 210 XXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISL 269 + + K+ E F + + + EK+ L E++ V +++++ K++E E++ Sbjct: 593 NKNEKENLQNKVDE-FEKIIDQLRKEKEVLE---ENEKVSKTNIDDDYKVIE----ELNN 644 Query: 270 EHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIE 329 E S L +++Q K+ + S E + + +E L+ N + IE Sbjct: 645 EKSDLQSKIDQLEKNNKDLTTNLELSNKEKSDLSLENENKRKEIDELKSLN-NKTNNDIE 703 Query: 330 LLEHLNCQIRQTNKELENKLATMGTESKAVSSP---SKKGSPLISRKSG--RNTASKMKS 384 L+ ++ ++N++L+ + + +E+ + S S+K +++++ ++ ++ + Sbjct: 704 KLQLQIQELEKSNEQLQKEKEVLSSENNQLKSNVENSEKEIGILNKEKADLQSKVEELDN 763 Query: 385 PWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXG 444 +L+S NQ+ K+ NE + L+ I+ L + E E + Sbjct: 764 NNKELASNLENQNKLNKVLNNENSDLQSKIEELTTKNQELESSNIETNNEKENLQARINE 823 Query: 445 KDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEK 504 + +I +LQ E++ ++E S H+ T+ ++ E+ +LN + D+ K I + Sbjct: 824 LEKIIDELQKENE-NLETESN-HLRTDLQN-------NEKTIADLNKDKNDLTSK--IGE 872 Query: 505 LKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSK-VSDSNKEIVRLTEE 563 L+ ++ T L D+I+A+NK++ + K+ ++K +D +K SD ++ L Sbjct: 873 LEKNNKEFTTLIDKINASNKDLQTKNDELQSKVDLLEKILDQLNKDKSDLITKLEELQTS 932 Query: 564 LHHLSQKVAELEEEKGNLQL---HLVDYDSGRMIESDVYKKMIE--MENLAETRLKAISL 618 + + Q L +E +LQ L++ + E++ K ++ ++ LAE +L + Sbjct: 933 IDQMKQTNENLNKENKDLQNKIEELLEENDKANNENESKNKELQQIIDQLAEEKLSLQNK 992 Query: 619 LESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKEL 678 E + + I+ + E E KL S ++V E LEE +EL Sbjct: 993 FEESEKNAKDNQKIIDELIAENE-KLT--SSNNEEKVELESLKNSLEETKQNDDKLVEEL 1049 Query: 679 ALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAK 738 + IE LK + + N+ + I+++L+ + M+ DKL K + ++ + Sbjct: 1050 SKEIEKLKNENNSILENSDSKNNENQQIIDQLKKEKSDLMNQVDKLTKKNEDQEKVIQDL 1109 Query: 739 INHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERK 798 IN + Q K + ++ + E IE I E KS + + +ES + R + + Sbjct: 1110 INDQNQ-KDEENKQMNDQSNELKSQIEKISIENETLKSDLQKNKESNGELMKEREISQSE 1168 Query: 799 ADQLGSYLQE-KQ---KAYSEYTIQEDELVNRLAVL-MDHDRVVEKQLLEIEHENKELQK 853 ++L L+E KQ K + + L N+L + DH +++++ E ++++ Sbjct: 1169 LEELKKLLEETKQNDNKLIDKLRNENQSLNNQLDMNNKDHQQIIDQFTKEESDLMSQIEE 1228 Query: 854 KNQILLEENQNLQ------ISLSDMQQHYNALVEK--------ANRTDLAESESTKYQTQ 899 N + E N N+Q +L+ + NAL+ + +N + S + + Q++ Sbjct: 1229 LNALNNELNVNIQNLEQDKSNLTKQNEELNALLNETKLQNQNLSNENETLRSNNERLQSE 1288 Query: 900 LRDLE----SNLKRITHEHQTLIVQ---KKKEIEDLEIEFNTQIESAIR---DKKVLNEK 949 L+ E S+ ++T + +TL + K K I++L+ + N ES + +K + + Sbjct: 1289 LKQNEEKSKSDFDQLTKDLETLKSEQSNKDKMIDELQNKTNDLEESIGKLNEEKAKITDS 1348 Query: 950 YEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKM--NLELIDKHVQKQQTQSPDYTEQY 1007 + + QL + + ++I N + +ELN +L +K + ++ + Sbjct: 1349 LTDRDQKIEQLNKEKSDLISDINNFEASQKELNDKIDSLNSANKDLNQENEKLKSQISSL 1408 Query: 1008 INEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRV 1067 NE + L + KD+EI ++NQ+++ S+ + S +ES+ + KL N+E + Sbjct: 1409 ENENSSLQSANNSKDKEIKSINQQLSETISSFDNYKSQHESEAEALSNKLNNLEANKDKS 1468 Query: 1068 SKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANN 1127 K+L + + E+LQ + QI+E +E +L+ + + + +E M + N+ Sbjct: 1469 EKELEELRNELEKLQ-----NEIQIREQREKELS-------NQNEELMNILEKMKSELND 1516 Query: 1128 VDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTG 1187 V+ LK EE ++ E S ++ ++ TK + Sbjct: 1517 VNMNNEQLDQEKEILKKSLEENQQNYDQLIDELSKEIEVLKKQLLTKDADSNS------- 1569 Query: 1188 HDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQRE 1247 ++ +I++L+SK++ L++EN+NL ST EL+ ++ + +EL Q Sbjct: 1570 ----SKHEIDELQSKIQNLSSENENLKSTNNELKQNLDDILKNNEQINSEL--TETKQTN 1623 Query: 1248 ADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTME-QVTSLQNKLQDKEEHL 1306 D L+ L + EQL+D + + E ++ + ++ L + + L Sbjct: 1624 KDLLSQIESLKKVLEENKQNDEQLVDELSKAPDEMKHEQQKKDNRIDKLTKEKETLHNTL 1683 Query: 1307 RNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXD---LRTENQSYKQMQ 1363 + + + +I ++ +SE+E E D L +N+ Sbjct: 1684 NSHDKDHQQIIEEMNKEKSELESELEKLKSLNKELNENNTKLNQDKSELIKQNEDLTNDN 1743 Query: 1364 EQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEY 1423 INE ++ + S N+ ++ E+ Q E + ++ + + Sbjct: 1744 NHKDEFINENQVKIDELSSLLNDLKSQLQNLSNENDSLKQEIEKQKETNE-KLQSELEDS 1802 Query: 1424 TITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEI- 1482 L + E + +++ L E ++ E L E E+ L+ E M K+ +I Sbjct: 1803 KENLEKSKSEIDPIQKSLEETKQNDEQLVDELTKEIEKLK---------NEQMTKDQKID 1853 Query: 1483 ERVKLIEELNVKITESVSLNKQVA-ELNKALEEEVAKTNEMQ---TALENQEIEIVTLND 1538 E K + LN + ++ N Q+ +LNK + +K NE++ + L +Q + ND Sbjct: 1854 ELTKENQSLNSSLEDNNKENDQIIDQLNKEKSDYESKLNELKQDHSDLMDQIESLAKKND 1913 Query: 1539 EI----TNLQNMVRASSSKIQKHVSFASDTK 1565 E+ N ++ ++ +I++ VS ++ K Sbjct: 1914 ELIKENNNKDQIINDNNQRIEELVSLSNKLK 1944 Score = 196 bits (479), Expect = 3e-48 Identities = 304/1360 (22%), Positives = 604/1360 (44%), Gaps = 132/1360 (9%) Query: 321 MTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISR-------K 373 + ELT+ E+L N ++ + N++L + ++ T + S + + I + Sbjct: 200 LDELTQNNEILSKDNEKLSKENEQLNQENTSLSTLLGSAKSTNLELENTIEQLKSANKEL 259 Query: 374 SGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEM-VIQSLNKDLVDK-----EYV 427 S +N + K Q E L DK + + E K E+ + + NK+L K + + Sbjct: 260 SDKNVEIQAKLINLQKEKEQLTSTNDKLLTETENLKKEIDELNNANKELNVKSINLQQSL 319 Query: 428 ISEKDTXXXXXXXXXXGKDTLIAQLQ-LEHQQHMEGPSLIHVGTNTED-----------V 475 +EK K LI++++ LE L +V T+ D V Sbjct: 320 DNEKQNNKKMIQDLNKEKTDLISKIEKLEMDNKEMNSKLNNVNTSYNDLDAKNQNNQTKV 379 Query: 476 NEIAKVQEQLKQELN-------------DEIKDVNVKDLIE-------KLKSAEEQITQL 515 N + K+ E+L +E DE+++ N KDLI K +S + +I QL Sbjct: 380 NNLEKIIEKLIKENTELANNNKNNNSKIDELQNQN-KDLISASNDMNTKNQSLQTKIDQL 438 Query: 516 N---DEIDAANK----NMIKVKSNHKLKLKQMQKTIDNFSKVSDS-NKEIVRLTEELHHL 567 N E++ NK N+ +KS+ K ++ K +N K+ D E L+ L + Sbjct: 439 NKEKTELEEKNKVLKSNLEGLKSDLLSKNQESTKKNENLQKIIDQLQNENKLLSSNLENQ 498 Query: 568 SQKVAELEEEKGNLQLHLVDYD-SGRMIESDV---YKKMIEMEN----LAETRLKAISLL 619 ++ +L +EK +LQ + + + + + + S++ +K + E+ N L + S L Sbjct: 499 TKLNDDLNKEKSDLQSKIEELEKNNKDLTSNLENNHKTIEELSNKINDLQNNNKELTSNL 558 Query: 620 ESQ---KFDLVQELHILQQKYDEVEDKLADI-SQLQSDQVCSEIKSVHLEEQIDALSASK 675 E Q DL +E LQ K +E+ K ++ S ++++ + K E+ ID L + Sbjct: 559 EDQNKLNDDLNKEKADLQSKIEELSTKNEELESSNKNEKENLQNKVDEFEKIIDQL---R 615 Query: 676 KELALVIENLKLDKEQL---YGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKI 732 KE ++ EN K+ K + Y I++L N+K D+ +K+ + N DLT LE + EK Sbjct: 616 KEKEVLEENEKVSKTNIDDDYKVIEELNNEKSDLQSKIDQLEKNNKDLTTNLELSNKEK- 674 Query: 733 SELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDR- 791 S+L + N ++ +I ++ K ++ EL K ++ + +E ++ ++ Sbjct: 675 SDLSLE-NENKRKEIDELKSLNNKTNNDIEKLQLQIQELEKSNEQLQKEKEVLSSENNQL 733 Query: 792 RYSLERKADQLGSYLQEKQKAYSEYTIQE-DELVNRLAVLMDHDRVVEKQLLEIEHENKE 850 + ++E ++G + K+KA + ++E D LA +++ + K L +EN + Sbjct: 734 KSNVENSEKEIG--ILNKEKADLQSKVEELDNNNKELASNLENQNKLNKVL---NNENSD 788 Query: 851 LQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRI 910 LQ K + L +NQ L+ S + L + N + E K L ++L+ Sbjct: 789 LQSKIEELTTKNQELESSNIETNNEKENLQARINELEKIIDELQKENENLETESNHLRTD 848 Query: 911 THEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNN 970 ++ I K+ DL + ++E ++ L +K + + L+ + E ++ Sbjct: 849 LQNNEKTIADLNKDKNDLTSKIG-ELEKNNKEFTTLIDKINASNK---DLQTKNDELQSK 904 Query: 971 IENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQ 1030 ++ L +++LNK +LI K +++ QT S D +Q +NK N L+ K EE++ N Sbjct: 905 VDLLEKILDQLNKDKSDLITK-LEELQT-SIDQMKQTNENLNKENKDLQNKIEELLEEND 962 Query: 1031 KINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSK---QLLDSK-QHNEELQILVR 1086 K NN S + +LA+ L+N EE ++ +K +++D NE+L Sbjct: 963 KANNENESKNKELQQIIDQLAEEKLSLQNKFEESEKNAKDNQKIIDELIAENEKLTSSNN 1022 Query: 1087 EQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQE 1146 E+ +++ LK + + N K +S IE + ++ N++ Q Sbjct: 1023 EEKVELESLKNSLEETKQNDDKLVEE-LSKEIEKLKNENNSI----LENSDSKNNENQQI 1077 Query: 1147 EEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQ--EQINQLKSKLE 1204 ++ +E+S L Q KL T+ E K+IQ + +N + + Q +Q N+LKS++E Sbjct: 1078 IDQLKKEKSDLMNQVDKL-TKKNEDQEKVIQ-DLINDQNQKDEENKQMNDQSNELKSQIE 1135 Query: 1205 QLNTENDNLLSTVAELRSSISSAVDQRGF---EIAELWKQHLAQREAD---FQKTEHE-- 1256 +++ EN+ L S + + + S + +R E+ EL K ++ D K +E Sbjct: 1136 KISIENETLKSDLQKNKESNGELMKEREISQSELEELKKLLEETKQNDNKLIDKLRNENQ 1195 Query: 1257 -LRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYAD 1315 L QL ++Q++D T+EE++ + +E++ +L N+L +++NL++ ++ Sbjct: 1196 SLNNQLDMNNKDHQQIIDQF---TKEESDLMSQIEELNALNNEL---NVNIQNLEQDKSN 1249 Query: 1316 VINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENA 1375 + Q E L + + + K+ L++E + ++ + + ++ Sbjct: 1250 LTKQNEELNALLNETKLQ-NQNLSNENETLRSNNERLQSELKQNEEKSKSDFDQLTKDLE 1308 Query: 1376 QLKKSSXXXXXXXXXXXXRVNDAEAKV-------LELTHQLELKDSEIYQKTHEYTITLT 1428 LK + ND E + ++T L +D +I Q E + ++ Sbjct: 1309 TLKSEQSNKDKMIDELQNKTNDLEESIGKLNEEKAKITDSLTDRDQKIEQLNKEKSDLIS 1368 Query: 1429 QRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLI 1488 N+ FE +++L + + + E L+ ++ N ++Q + + K I Sbjct: 1369 DINN-FEASQKELNDKIDSLNSANKDLNQENEKLKSQISSLENENSSLQSANN-SKDKEI 1426 Query: 1489 EELNVKITESVSLNKQVAELNKALEEEVA-KTNEMQTALENQEIEIVTLNDEITNLQNMV 1547 + +N +++E++S +++ E ++ K N ++ + E E+ L +E+ LQN + Sbjct: 1427 KSINQQLSETISSFDNYKSQHESEAEALSNKLNNLEANKDKSEKELEELRNELEKLQNEI 1486 Query: 1548 RASSSKIQKHVSFASD-----TKQGRDEQLDNTMNKELLD 1582 + + +K +S ++ ++ + E D MN E LD Sbjct: 1487 QIREQR-EKELSNQNEELMNILEKMKSELNDVNMNNEQLD 1525 Score = 191 bits (466), Expect = 1e-46 Identities = 326/1585 (20%), Positives = 680/1585 (42%), Gaps = 163/1585 (10%) Query: 140 QLGD-VTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXX 198 +L D + L++ K+ + L+ ++ +E LQ N KD+ I++ N+ + Sbjct: 1379 ELNDKIDSLNSANKDLNQENEKLKSQISSLENENSSLQSANNSKDKEIKSINQQLSETIS 1438 Query: 199 XXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKD---EKQRLLKDIESKDVRISSL-- 253 E ++ ++ N E E ++ E ++L +I+ ++ R L Sbjct: 1439 SFDNYKSQHESEAEALSNKLNNLEANKDKSEKELEELRNELEKLQNEIQIREQREKELSN 1498 Query: 254 --EEANKLLEAARFE---ISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQ---SIEPSCE 305 EE +LE + E +++ + +L QE E L + IE + Sbjct: 1499 QNEELMNILEKMKSELNDVNMNNEQLDQEKEILKKSLEENQQNYDQLIDELSKEIEVLKK 1558 Query: 306 EKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSP--- 362 + + + + EL KI+ L N ++ TN EL+ L + ++ ++S Sbjct: 1559 QLLTKDADSNSSKHEIDELQSKIQNLSSENENLKSTNNELKQNLDDILKNNEQINSELTE 1618 Query: 363 -SKKGSPLISR-KSGRNTASKMKSPWSQLSSETLNQDTDKKINK----NEIAKL----EM 412 + L+S+ +S + + K QL E + K + N I KL E Sbjct: 1619 TKQTNKDLLSQIESLKKVLEENKQNDEQLVDELSKAPDEMKHEQQKKDNRIDKLTKEKET 1678 Query: 413 VIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQ-HMEGPSLIH---- 467 + +LN D + +I E + +L +L + + + + LI Sbjct: 1679 LHNTLNSHDKDHQQIIEEMNKEKSELESELEKLKSLNKELNENNTKLNQDKSELIKQNED 1738 Query: 468 -----------VGTNTEDVNEIAKVQEQLKQEL-NDEIKDVNVKDLIEKLKSAEEQITQL 515 + N ++E++ + LK +L N ++ ++K IEK K E+ L Sbjct: 1739 LTNDNNHKDEFINENQVKIDELSSLLNDLKSQLQNLSNENDSLKQEIEKQKETNEK---L 1795 Query: 516 NDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDS-NKEIVRLTEELHHLSQKVAEL 574 E++ + +N+ K KS K +++T N ++ D KEI +L E QK+ EL Sbjct: 1796 QSELEDSKENLEKSKSEIDPIQKSLEETKQNDEQLVDELTKEIEKLKNEQMTKDQKIDEL 1855 Query: 575 EEEKGNLQLHLVDY--DSGRMIE------SDVYKKMIEMENLAETRLKAISLLESQKFDL 626 +E +L L D ++ ++I+ SD K+ E++ + I L + +L Sbjct: 1856 TKENQSLNSSLEDNNKENDQIIDQLNKEKSDYESKLNELKQDHSDLMDQIESLAKKNDEL 1915 Query: 627 VQELH----ILQQKYDEVEDKLA---------DISQLQSDQVCSEIKSVHLEEQIDALSA 673 ++E + I+ +E+ ++ ++ +++ + SEI+ H E I+ L Sbjct: 1916 IKENNNKDQIINDNNQRIEELVSLSNKLKPQIEVLSKENESLKSEIQRNH--ENIEKLQQ 1973 Query: 674 SKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKIS 733 E EN + + L +++ N+ +MN +N E D ++++ EK + Sbjct: 1974 KLDESQQTNENSSNEIDNLKKLLEEANNNHNQLMNDFENLKHEISDKDKMIQEL--EKRN 2031 Query: 734 ELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDR-- 791 + N + +K++ +AKI E D IE + EL K L+E++ ME++ Sbjct: 2032 DANNNQNSDLSAKLKES---EAKISELDSQIEKYKQELEKLMKMNNELKETVQEMENQIQ 2088 Query: 792 -----RYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLA----VLMDHDRVVEKQLL 842 +L+ + D+ + Q +E + L++++ +L ++D EK Sbjct: 2089 NISNENVNLKTEVDKSKENSNKLQNDLNEAKQNNENLLSQIESLKKLLEENDANFEKMKS 2148 Query: 843 EIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANR----------TDLAESE 892 E+ + +Q EN+ L+ SL + QQ+Y+ LV++ ++ T ES Sbjct: 2149 ELNDAKMNKEHSDQ----ENETLKKSLEENQQNYDQLVDELSKEIEELKKQLLTKAEESN 2204 Query: 893 STKYQTQLRDLESNLKRITHEHQTLIV---QKKKEIEDLEIEFNTQIESAIRDKKVLNEK 949 S+K++ + +L+S ++ ++ E++ L + K+ ++D+ ++ N QI S + + K N+ Sbjct: 2205 SSKHE--IDELQSKIQNLSSENENLKSTNNELKQNLDDI-LKNNEQINSELTETKQTNKD 2261 Query: 950 YEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQ-KQQTQSPDYTEQYI 1008 IE L+ L+E K N E L V+EL+K E+ KH Q K+ + + T++ Sbjct: 2262 LLSQIE---SLKKVLEENKQNDEQL---VDELSKAPDEM--KHEQQKKDNRIDELTKEKE 2313 Query: 1009 NEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVS 1068 N LN+ KD + I +++N + S + +YES+L + + + + E +++ Sbjct: 2314 TLYNTLNS--HDKDHQQII--EEMNKEKSELGSQIHEYESELDKLKSLNKELNENNTKLN 2369 Query: 1069 KQLLDSKQHNEEL----QILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDD 1124 + + + NE+L L+ Q+D+ + + E K + +P + S ++ +S++ Sbjct: 2370 QDKSELIKQNEDLTRNNNDLINAQNDKDRIINENKAKID-ELPSLLNDL-QSHLQNLSNE 2427 Query: 1125 ANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQ--EQSAKLNTELQECYTKIIQL---E 1179 N++ K EE+ I+ + + E++ + + +L + TK I+ E Sbjct: 2428 NNSLKQEVEKLQTELGDSKQNEEKSKIESEQMKKSLEETKQNDEQLVDELTKEIEKLKNE 2487 Query: 1180 TLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAEL- 1238 LN + T ++ N+ + + L+ N E + ++ + + S S ++ ++ EL Sbjct: 2488 QLNKDRTIQNLTNKNE--SINKNLDSNNKEYEQIIDQLNQDLSESKSKLNDYETKMNELN 2545 Query: 1239 -WKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQN 1297 + L + ++ + +L Q+ K E L++ +Q + K ++Q+ N Sbjct: 2546 LLNKELQKDNETLKENQSDLINQIEELSKKNENLIN-LQGTNSNLVLKNDELQQLIDKLN 2604 Query: 1298 K-----LQDKEEHLRN---LQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXX 1349 K +Q+ E +N EK + IE +++ ++ Sbjct: 2605 KEKSDLIQENERLTKNNGESNEKLQSLDQMIETVKNNSSEKDKENHQIIDQLNKEKLDLS 2664 Query: 1350 XDLRT-ENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQ 1408 L+ ENQ + + S+ +N++N +L+ + +++ E++ L Sbjct: 2665 SKLKDYENQL--DVLKSSLKELNDKNKELQNGNDILKQENETLTPKISSLESENSSLKST 2722 Query: 1409 LELKDSEIY---QKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKE---SELAIL 1462 E+KD EI QK E + +Q + ++ R+Q +EK +E+L + E +E+ I Sbjct: 2723 NEIKDKEIEELKQKLSEISQLNSQHESDLDSRRKQ---FEKELEELRNQLEKLQNEIQIR 2779 Query: 1463 RLKMHENANHYETMQK-----ESEIERVKLIEELNVKITESV--SLNKQVAELNKALEEE 1515 + E +N E + +SE+ K+ +E + + E++ SL + ++ ++E Sbjct: 2780 EQRGKELSNQNEELMNNLEKMKSELNDAKMNKEHSDQENETLKKSLEENQQNYDQLVDEL 2839 Query: 1516 VAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNT 1575 + E++ L + E + EI LQ+ ++ SS+ + S ++ KQ + ++ Sbjct: 2840 SKEIEELKKQLLTKAEESNSSKHEIDELQSKIQNLSSENENLKSTNNELKQQIESLKNDL 2899 Query: 1576 MNKELLDAVPRAELDLAMYMLHQRD 1600 NK+ + E+D + H+ + Sbjct: 2900 QNKDQIVEELTKEIDSSNKQSHENN 2924 Score = 180 bits (437), Expect = 4e-43 Identities = 323/1539 (20%), Positives = 641/1539 (41%), Gaps = 146/1539 (9%) Query: 158 LSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQ 217 L L+ + + I +LQ K N+ ++ I N+ ++ K Sbjct: 1307 LETLKSEQSNKDKMIDELQNKTNDLEESIGKLNEEKAKITDSLTDRDQKIEQLNKE-KSD 1365 Query: 218 MTKMQENFIAMEAEWKDEKQRLL---KDIESKDVR----ISSLEEANKLLEAARFEISLE 270 + NF A + E D+ L KD+ ++ + ISSLE N L++A E Sbjct: 1366 LISDINNFEASQKELNDKIDSLNSANKDLNQENEKLKSQISSLENENSSLQSANNSKDKE 1425 Query: 271 HSKLAQELEQXXXXXXXXXXXXXXLAKQSIEP--SCEEKTEIEEKGSLEIANMTE-LTKK 327 + Q+L + A+ + E + EK E+ N E L + Sbjct: 1426 IKSINQQLSETISSFDNYKSQHESEAEALSNKLNNLEANKDKSEKELEELRNELEKLQNE 1485 Query: 328 IELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKK--GSPLISRKSGRNTASKMKSP 385 I++ E ++ N+EL N L M +E V+ +++ I +KS Sbjct: 1486 IQIREQREKELSNQNEELMNILEKMKSELNDVNMNNEQLDQEKEILKKSLEENQQNYDQL 1545 Query: 386 WSQLSSET-------LNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXX 438 +LS E L +D D +K+EI +L+ IQ+L+ + E + S + Sbjct: 1546 IDELSKEIEVLKKQLLTKDADSNSSKHEIDELQSKIQNLSSE---NENLKSTNNELKQNL 1602 Query: 439 XXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELN---DEIKD 495 + + ++L Q + + L + + + + E + EQL EL+ DE+K Sbjct: 1603 DDILKNNEQINSELTETKQTNKD--LLSQIESLKKVLEENKQNDEQLVDELSKAPDEMKH 1660 Query: 496 VNVK--DLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKL-------KLKQMQKTI-D 545 K + I+KL +E + + D ++ +I+ + K KLK + K + + Sbjct: 1661 EQQKKDNRIDKLTKEKETLHNTLNSHDKDHQQIIEEMNKEKSELESELEKLKSLNKELNE 1720 Query: 546 NFSKVSDSNKEIVRLTEEL----HHLSQKVAELEEEKGNLQLHLVDYDS---GRMIESDV 598 N +K++ E+++ E+L +H + + E + + L L D S E+D Sbjct: 1721 NNTKLNQDKSELIKQNEDLTNDNNHKDEFINENQVKIDELSSLLNDLKSQLQNLSNENDS 1780 Query: 599 YKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSE 658 K+ IE + ET K S LE K +L + + +E+ + QL D++ E Sbjct: 1781 LKQEIEKQK--ETNEKLQSELEDSKENLEKSKSEIDPIQKSLEETKQNDEQLV-DELTKE 1837 Query: 659 IKSVHLEE-----QIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNY 713 I+ + E+ +ID L+ + L +E+ + +Q+ I L +K D +KL Sbjct: 1838 IEKLKNEQMTKDQKIDELTKENQSLNSSLEDNNKENDQI---IDQLNKEKSDYESKLNEL 1894 Query: 714 IQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSK 773 Q++ DL D++E + A+K EL+ + N+++Q I + + IE + S +K Sbjct: 1895 KQDHSDLMDQIESL-AKKNDELIKENNNKDQI-----------INDNNQRIEELVSLSNK 1942 Query: 774 YKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDH 833 K +I L + ++ ++L L E Q+ + + D L L ++ Sbjct: 1943 LKPQIEVLSKENESLKSEIQRNHENIEKLQQKLDESQQTNENSSNEIDNLKKLLEEANNN 2002 Query: 834 DRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESES 893 + ++HE + K Q L + N SD+ L E + +S+ Sbjct: 2003 HNQLMNDFENLKHEISDKDKMIQELEKRNDANNNQNSDLSA---KLKESEAKISELDSQI 2059 Query: 894 TKYQTQLRDL---ESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKY 950 KY+ +L L + LK E + I E +L+ E + E++ + + LNE Sbjct: 2060 EKYKQELEKLMKMNNELKETVQEMENQIQNISNENVNLKTEVDKSKENSNKLQNDLNEAK 2119 Query: 951 EKNIEYVTQLEAQLQEYKNNIENLNMNVEELN--KMNLELIDKHVQKQQTQSPDYTEQYI 1008 + N ++Q+E+ + + N N ELN KMN E D+ + + + + Y Sbjct: 2120 QNNENLLSQIESLKKLLEENDANFEKMKSELNDAKMNKEHSDQENETLKKSLEENQQNYD 2179 Query: 1009 NEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENME----EEM 1064 +++L+ +++ ++++ ++ N+++ + + +SK+ +++ EN++ E Sbjct: 2180 QLVDELSKEIEELKKQLLTKAEESNSSK----HEIDELQSKIQNLSSENENLKSTNNELK 2235 Query: 1065 QRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMI--ISSTIEPMS 1122 Q + L +++Q N EL + D + +++ K E N E ++ +S + M Sbjct: 2236 QNLDDILKNNEQINSELTETKQTNKDLLSQIESLKKVLEENKQNDEQLVDELSKAPDEMK 2295 Query: 1123 DDA----NNVDXXXXXXXXXXXXLKVQEE------EEFIQERSVLQEQ----------SA 1162 + N +D L ++ EE +E+S L Q Sbjct: 2296 HEQQKKDNRIDELTKEKETLYNTLNSHDKDHQQIIEEMNKEKSELGSQIHEYESELDKLK 2355 Query: 1163 KLNTELQECYTKIIQ----LETLNTELT--GHDVVNQEQ-----INQLKSKLEQLNTEND 1211 LN EL E TK+ Q L N +LT +D++N + IN+ K+K+++L + + Sbjct: 2356 SLNKELNENNTKLNQDKSELIKQNEDLTRNNNDLINAQNDKDRIINENKAKIDELPSLLN 2415 Query: 1212 NLLSTVAEL---RSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKY 1268 +L S + L +S+ V++ E+ + KQ+ + + + ++ + L E Sbjct: 2416 DLQSHLQNLSNENNSLKQEVEKLQTELGDS-KQNEEKSKIESEQMKKSLEETKQNDEQLV 2474 Query: 1269 EQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIE 1328 ++L ++ E+ NK T++ +T NK + ++L + ++Y +I+Q+ SE + Sbjct: 2475 DELTKEIEKLKNEQLNKDRTIQNLT---NKNESINKNLDSNNKEYEQIIDQLNQDLSESK 2531 Query: 1329 DEKVAFXXXXXXXXXXXXXXXXDLRT--ENQS--YKQMQEQSILNINEENAQLKKSS-XX 1383 + + D T ENQS Q++E S N N N Q S+ Sbjct: 2532 SKLNDYETKMNELNLLNKELQKDNETLKENQSDLINQIEELSKKNENLINLQGTNSNLVL 2591 Query: 1384 XXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTH---EYTITLTQRNDEFENVRQQ 1440 ++N ++ +++ +L + E +K + T+ + E + Q Sbjct: 2592 KNDELQQLIDKLNKEKSDLIQENERLTKNNGESNEKLQSLDQMIETVKNNSSEKDKENHQ 2651 Query: 1441 LV-EYEKRIEDLT---YEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKIT 1496 ++ + K DL+ + E++L +L+ + E + + +Q ++I + + E L KI+ Sbjct: 2652 IIDQLNKEKLDLSSKLKDYENQLDVLKSSLKELNDKNKELQNGNDILKQE-NETLTPKIS 2710 Query: 1497 ESVSLNKQVAELN----KALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSS 1552 S N + N K +EE K +E+ E ++ + + +R Sbjct: 2711 SLESENSSLKSTNEIKDKEIEELKQKLSEISQLNSQHESDLDSRRKQFEKELEELRNQLE 2770 Query: 1553 KIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDL 1591 K+Q + ++ R ++L N N+EL++ + + + +L Sbjct: 2771 KLQNEIQI----REQRGKELSN-QNEELMNNLEKMKSEL 2804 Score = 174 bits (424), Expect = 1e-41 Identities = 306/1501 (20%), Positives = 628/1501 (41%), Gaps = 161/1501 (10%) Query: 147 LSNTIKEKDNALSVLQVKMKIMETTILDLQEKI----NEKDQIIEAKNKATTXXXXXXXX 202 L N +KD ++ + K+ + + + DLQ + NE + + + K T Sbjct: 2389 LINAQNDKDRIINENKAKIDELPSLLNDLQSHLQNLSNENNSLKQEVEKLQTELGDSKQN 2448 Query: 203 XXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSL----EEANK 258 E K+ + + ++N + E E ++L + +KD I +L E NK Sbjct: 2449 EEKSKIES-EQMKKSLEETKQNDEQLVDELTKEIEKLKNEQLNKDRTIQNLTNKNESINK 2507 Query: 259 LLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEI 318 L++ E +L Q+L + L + E + +T E + L I Sbjct: 2508 NLDSNNKEYEQIIDQLNQDLSESKSKLNDYETKMNELNLLNKELQKDNETLKENQSDL-I 2566 Query: 319 ANMTELTKKIELLEHL---NCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSG 375 + EL+KK E L +L N + N EL+ + + E + +++ +++ +G Sbjct: 2567 NQIEELSKKNENLINLQGTNSNLVLKNDELQQLIDKLNKEKSDLIQENER----LTKNNG 2622 Query: 376 RNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXX 435 + K++S + ET+ ++ +K +N +I LNK+ +D + + + Sbjct: 2623 ESN-EKLQSLDQMI--ETVKNNSSEKDKENH-----QIIDQLNKEKLDLSSKLKDYENQL 2674 Query: 436 XXXXXXXXGKDTLIAQLQ-----LEHQQHMEGP---SLIHVGTNTEDVNEIA-KVQEQLK 486 + +LQ L+ + P SL ++ + NEI K E+LK Sbjct: 2675 DVLKSSLKELNDKNKELQNGNDILKQENETLTPKISSLESENSSLKSTNEIKDKEIEELK 2734 Query: 487 QELND--EIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLK-QMQKT 543 Q+L++ ++ + DL + K E+++ +L ++++ +N I+++ +L Q ++ Sbjct: 2735 QKLSEISQLNSQHESDLDSRRKQFEKELEELRNQLEKL-QNEIQIREQRGKELSNQNEEL 2793 Query: 544 IDNFSKV-------------SDSNKEIVR--LTEELHHLSQKVAELEEEKGNLQLHLV-- 586 ++N K+ SD E ++ L E + Q V EL +E L+ L+ Sbjct: 2794 MNNLEKMKSELNDAKMNKEHSDQENETLKKSLEENQQNYDQLVDELSKEIEELKKQLLTK 2853 Query: 587 --DYDSGRM----IESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEV 640 + +S + ++S + E ENL T + +ES K DL + I+++ E+ Sbjct: 2854 AEESNSSKHEIDELQSKIQNLSSENENLKSTNNELKQQIESLKNDLQNKDQIVEELTKEI 2913 Query: 641 EDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELAL-------VIENLKLDKEQLY 693 + ++ +++++ ++ K + L +QI+ L+ + E+ +I +LK+ E+L Sbjct: 2914 DS--SNKQSHENNELLNQ-KQLDLMKQIEDLTKKQGEMLKQNQNQENIINDLKIKNEELT 2970 Query: 694 --GTIKD-----LENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQS- 745 G KD L D + +QN EN L L+ ++L K+N +Q+ Sbjct: 2971 KEGNNKDKVINELNKSLNDFKSLIQNLSNENEKLKSALQNSQGNN-ADLQQKLNSTQQND 3029 Query: 746 -KIQTQFGIDAK-IQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLG 803 + Q + K +QE +N+ +E+ K ++ I + + L K Q+ Sbjct: 3030 QNLLNQIELLKKSLQENKQNEDNLVNEIQNQKIENQNKDQIIEDLRKKNEELNLKQQQIQ 3089 Query: 804 SYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQ 863 K+K+ +Q L L+ ++ +E++ ++ ++ +L+KKN+IL ++ Sbjct: 3090 DQFN-KEKSGLISKLQGLNLSGN--ELLSNNEKLEQEQSDLMNQINDLRKKNEILNQQQA 3146 Query: 864 NLQISLSDMQQHYNALVEKAN----RTDLAESESTKYQTQLRDLESNLKRITHEHQTLIV 919 N + + Q+ E N + + A + + + Q+ L+ L+ L+ Sbjct: 3147 NNNQIIKECQEKIQNYEESNNELQRKLNEAMNNNENAKNQIDQLKKLLEETKQNDDKLVE 3206 Query: 920 QKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVE 979 + KEIE L+ E ++ ++ I D LN+ I+ L + QE+ N+ +N +E Sbjct: 3207 ELTKEIEKLKNEQQSKDQN-INDLSALNKDKSSLIQQNDDLSKKTQEFYNSQQNQAQMIE 3265 Query: 980 ELNKMN------LELIDKHVQ-------KQQTQSPDYTEQYINEINKLNALLKQKDEEII 1026 +L K N LE+ + Q K ++ Y +IN LN+L+K+ +E+ Sbjct: 3266 DLKKQNESLQKNLEINNNETQQNIDQLTKDKSDLASKLHDYEAKINDLNSLIKELNEKN- 3324 Query: 1027 ALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVR 1086 A+ +K N + + +D SK Q ++ + ++ +SKQ+ D N E+ + Sbjct: 3325 AIIEKKNYEFSQQLEVNNDLISKNNQLQQTIDQLNKDKTVLSKQIQDLANKNNEITNQLN 3384 Query: 1087 EQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQE 1146 +D I E K+ + E+N + M T++ +DD N+ L++++ Sbjct: 3385 NKDKIILESKQK--SDELNQSLSNLMKELHTLKANNDDLNS-QISQSKQNEENLQLQIEK 3441 Query: 1147 EEEFIQE-----RSVLQEQSAKLNTELQEC-------------YTKII-QLETLNTELTG 1187 +++ +Q+ ++ + S ++ T E Y+ I+ QL+ N E+ Sbjct: 3442 QKKLLQDTKQNDNKLVDDLSKEVETLTSEKLKNEEIIKQNNAKYSGILKQLQQKNEEINK 3501 Query: 1188 ------HDVVNQEQ--------INQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGF 1233 HD+ ++Q +NQ K KL Q N + + L + I++ Q+ Sbjct: 3502 EKEQFKHDLEGEKQKNEKLVNDLNQTKDKLSQENEKLKHYLVAFKQNNEQITADNKQKDE 3561 Query: 1234 EIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVT 1293 I +L KQ + ++ Q+ E +L+ Q + + Y+ L++ + + T+ ++ + Sbjct: 3562 NIQQLMKQ-INSLKSQLQEDE-KLKSQFAKMKENYDSLINKLNQENKSLTH---SLNESL 3616 Query: 1294 SLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLR 1353 +L E L+ E ++ +NQ+ + + E L Sbjct: 3617 KHNEELSKNNEKLQQNNELLSNKLNQLGSQDNNKQKEIENMNQKLQKVSNEGKQKEDQLI 3676 Query: 1354 TENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKD 1413 E + K S++ + +N + + + N+ + EL + + K+ Sbjct: 3677 EEINNLKF----SLIELQRKNEDMNQMLSETKKQNEVLSEQNNEIQLLKNELENLSKSKE 3732 Query: 1414 SEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHY 1473 EI EY + ++ DE E++ + +K+ E +YEK K E Y Sbjct: 3733 DEINSLKEEYERKIKEKEDEIEHLEENCNNEKKKTE--SYEK---------KFVEEKGEY 3781 Query: 1474 ETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEI 1533 E+ Q+ +E +L E+ + + E+ L+K + + A++ E K E L+ + Sbjct: 3782 ESKQQNTETYIEELETEIELLLKENEQLDKTKYDYD-AIQHEYNKVREDLAKLQKEHDNF 3840 Query: 1534 V 1534 V Sbjct: 3841 V 3841 Score = 173 bits (422), Expect = 3e-41 Identities = 243/1184 (20%), Positives = 521/1184 (44%), Gaps = 98/1184 (8%) Query: 472 TEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKS 531 ++D +++K EQL QE + ++ L+ KS ++ +++ +ANK + Sbjct: 211 SKDNEKLSKENEQLNQE------NTSLSTLLGSAKSTNLELENTIEQLKSANKELSDKNV 264 Query: 532 NHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSG 591 + KL +QK + + +D +L E +L +++ EL L + ++ Sbjct: 265 EIQAKLINLQKEKEQLTSTND------KLLTETENLKKEIDELNNANKELNVKSINLQQS 318 Query: 592 RMIESDVYKKMIEMENLAETRL-KAISLLESQKFDLVQELHILQQKYDEVEDKLADISQL 650 E KKMI+ N +T L I LE ++ +L+ + Y++++ K + +Q Sbjct: 319 LDNEKQNNKKMIQDLNKEKTDLISKIEKLEMDNKEMNSKLNNVNTSYNDLDAKNQN-NQT 377 Query: 651 QSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKL 710 + + + I+ + ++E + L+ + K I+ L+ + L D+ + + K+ Sbjct: 378 KVNNLEKIIEKL-IKENTE-LANNNKNNNSKIDELQNQNKDLISASNDMNTKNQSLQTKI 435 Query: 711 QNYIQENMDLTDKLE--KMSAEKI-SELLAKINHEEQSKIQTQFGIDAKIQERDLYIENI 767 +E +L +K + K + E + S+LL+K + Q ID E L N+ Sbjct: 436 DQLNKEKTELEEKNKVLKSNLEGLKSDLLSKNQESTKKNENLQKIIDQLQNENKLLSSNL 495 Query: 768 ESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNR- 826 E++ L + + ++ + LE+ L S L+ K E + + ++L N Sbjct: 496 ENQTKLNDD----LNKEKSDLQSKIEELEKNNKDLTSNLENNHKTIEELSNKINDLQNNN 551 Query: 827 ---LAVLMDHDRV---VEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALV 880 + L D +++ + K+ +++ + +EL KN+ L N+N + +L + + ++ Sbjct: 552 KELTSNLEDQNKLNDDLNKEKADLQSKIEELSTKNEELESSNKNEKENLQNKVDEFEKII 611 Query: 881 EKANRTDLAESESTKY-QTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESA 939 ++ + E+ K +T + D ++ + +E L K ++E + T +E + Sbjct: 612 DQLRKEKEVLEENEKVSKTNIDDDYKVIEELNNEKSDL-QSKIDQLEKNNKDLTTNLELS 670 Query: 940 IRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELI-DKHV----Q 994 ++K L+ + E + + +L++ + N+IE L + ++EL K N +L +K V Sbjct: 671 NKEKSDLSLENENKRKEIDELKSLNNKTNNDIEKLQLQIQELEKSNEQLQKEKEVLSSEN 730 Query: 995 KQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFT 1054 Q + + +E+ I +NK A L+ K EE+ N+++ + + + ++ + Sbjct: 731 NQLKSNVENSEKEIGILNKEKADLQSKVEELDNNNKELASNLENQNKLNKVLNNENSDLQ 790 Query: 1055 TKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKEL-KETK-LTFEMNIPKTEGM 1112 +K+E + + Q + +++ E LQ + E + I EL KE + L E N +T+ Sbjct: 791 SKIEELTTKNQELESSNIETNNEKENLQARINELEKIIDELQKENENLETESNHLRTDLQ 850 Query: 1113 IISSTIEPMSDDAN------------NVDXXXXXXXXXXXXLKVQEEEEFIQER-SVLQE 1159 TI ++ D N N + +Q + + +Q + +L++ Sbjct: 851 NNEKTIADLNKDKNDLTSKIGELEKNNKEFTTLIDKINASNKDLQTKNDELQSKVDLLEK 910 Query: 1160 QSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAE 1219 +LN + + TK+ +L+T ++ + ++ L++K+E+L END + Sbjct: 911 ILDQLNKDKSDLITKLEELQTSIDQMKQTNENLNKENKDLQNKIEELLEENDKANNENES 970 Query: 1220 LRSSISSAVDQRGFEIAELW-KQHLAQREA-DFQKTEHELRVQ---LSAFESKYEQLLDS 1274 + +DQ E L K +++ A D QK EL + L++ ++ + L+S Sbjct: 971 KNKELQQIIDQLAEEKLSLQNKFEESEKNAKDNQKIIDELIAENEKLTSSNNEEKVELES 1030 Query: 1275 VQSS---TQEETNKIVT--MEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIED 1329 +++S T++ +K+V +++ L+N+ E+ + + +I+Q++ +S++ + Sbjct: 1031 LKNSLEETKQNDDKLVEELSKEIEKLKNENNSILENSDSKNNENQQIIDQLKKEKSDLMN 1090 Query: 1330 EKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQS------ILNINEENAQLKKSSXX 1383 + D +++ KQM +QS I I+ EN LK Sbjct: 1091 QVDKLTKKNEDQEKVIQDLINDQNQKDEENKQMNDQSNELKSQIEKISIENETLKSDLQK 1150 Query: 1384 XXXXXXXXXXRVNDAEAKVLELTHQLE---LKDSEIYQKTHEYTITLTQRNDEFENVRQQ 1440 +++++ EL LE D+++ K +L + D QQ Sbjct: 1151 NKESNGELMKEREISQSELEELKKLLEETKQNDNKLIDKLRNENQSLNNQLDMNNKDHQQ 1210 Query: 1441 LVE-YEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESV 1499 +++ + K DL + E EL L +++ N + E Q +S + K EELN + E+ Sbjct: 1211 IIDQFTKEESDLMSQIE-ELNALNNELNVNIQNLE--QDKSNL--TKQNEELNALLNETK 1265 Query: 1500 SLNKQVAELNKALE-------------EEVAK------TNEMQTALENQEIEIVTLNDEI 1540 N+ ++ N+ L EE +K T +++T L++++ + DE+ Sbjct: 1266 LQNQNLSNENETLRSNNERLQSELKQNEEKSKSDFDQLTKDLET-LKSEQSNKDKMIDEL 1324 Query: 1541 TNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAV 1584 N N + S K+ + + +D+ RD++++ +NKE D + Sbjct: 1325 QNKTNDLEESIGKLNEEKAKITDSLTDRDQKIEQ-LNKEKSDLI 1367 Score = 169 bits (412), Expect = 4e-40 Identities = 304/1466 (20%), Positives = 620/1466 (42%), Gaps = 129/1466 (8%) Query: 174 DLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWK 233 DL N+KD+II +NKA ++ + +++ ++ E Sbjct: 2388 DLINAQNDKDRIIN-ENKAKIDELPSLLNDLQSHL---QNLSNENNSLKQEVEKLQTELG 2443 Query: 234 DEKQRLLKD-IESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXX 292 D KQ K IES+ ++ SLEE + E E++ E KL E Sbjct: 2444 DSKQNEEKSKIESEQMK-KSLEETKQNDEQLVDELTKEIEKLKNEQLNKDRTIQNLTNKN 2502 Query: 293 XXLAKQSIEPSCEEKTEIEEKGSLEIAN----MTELTKKIELLEHLNCQIRQTNKELENK 348 + K +++ + +E +I ++ + +++ + + K+ L LN ++++ N+ L+ Sbjct: 2503 ESINK-NLDSNNKEYEQIIDQLNQDLSESKSKLNDYETKMNELNLLNKELQKDNETLKEN 2561 Query: 349 LATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIA 408 + + + + SKK LI+ + G N+ +K+ Q + LN++ I +NE Sbjct: 2562 QSDLINQ---IEELSKKNENLINLQ-GTNSNLVLKNDELQQLIDKLNKEKSDLIQENE-- 2615 Query: 409 KLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHV 468 +L N+ L + +I +T +I QL E + + Sbjct: 2616 RLTKNNGESNEKLQSLDQMI---ETVKNNSSEKDKENHQIIDQLNKEK---------LDL 2663 Query: 469 GTNTEDVNEIAKVQEQLKQELNDEIKDV-NVKDLIEKLKSAEEQITQLNDEIDAANKNMI 527 + +D V + +ELND+ K++ N D+ LK E +T +++ N ++ Sbjct: 2664 SSKLKDYENQLDVLKSSLKELNDKNKELQNGNDI---LKQENETLTPKISSLESENSSL- 2719 Query: 528 KVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVR-LTEELHHLSQKVAELEEEKGNLQLHL- 585 KS +++K K++++ S++S N + L +++ EL + LQ + Sbjct: 2720 --KSTNEIKDKEIEELKQKLSEISQLNSQHESDLDSRRKQFEKELEELRNQLEKLQNEIQ 2777 Query: 586 VDYDSGRMIESDVYKKMIEMENLAETRLKAISLLE---SQKFDLVQELHILQQKYDEVED 642 + G+ + + + M +E + A E + L + L QQ YD++ D Sbjct: 2778 IREQRGKELSNQNEELMNNLEKMKSELNDAKMNKEHSDQENETLKKSLEENQQNYDQLVD 2837 Query: 643 KLA-DISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLEN 701 +L+ +I +L+ + +S + +ID L + + L+ ENLK +L I+ L+N Sbjct: 2838 ELSKEIEELKKQLLTKAEESNSSKHEIDELQSKIQNLSSENENLKSTNNELKQQIESLKN 2897 Query: 702 D---KEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQ 758 D K+ I+ +L I + + + ++ +K +L+ +I E+ +K Q + + Q Sbjct: 2898 DLQNKDQIVEELTKEIDSSNKQSHENNELLNQKQLDLMKQI--EDLTKKQGEMLKQNQNQ 2955 Query: 759 ER---DLYIENIE--SELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAY 813 E DL I+N E E + I L +S+ + +L + ++L S LQ Q Sbjct: 2956 ENIINDLKIKNEELTKEGNNKDKVINELNKSLNDFKSLIQNLSNENEKLKSALQNSQGNN 3015 Query: 814 SEY------TIQEDE-LVNRLAVL---MDHDRVVEKQLL-EIEHENKELQKKNQI---LL 859 ++ T Q D+ L+N++ +L + ++ E L+ EI+++ E Q K+QI L Sbjct: 3016 ADLQQKLNSTQQNDQNLLNQIELLKKSLQENKQNEDNLVNEIQNQKIENQNKDQIIEDLR 3075 Query: 860 EENQNLQISLSDMQQHYN----ALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQ 915 ++N+ L + +Q +N L+ K +L+ +E +L +S+L ++ Sbjct: 3076 KKNEELNLKQQQIQDQFNKEKSGLISKLQGLNLSGNELLSNNEKLEQEQSDLMNQIND-- 3133 Query: 916 TLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLN 975 ++KK EI + + N QI ++K + YE E +L+ +L E NN EN Sbjct: 3134 ---LRKKNEILNQQQANNNQIIKECQEKI---QNYE---ESNNELQRKLNEAMNNNENAK 3184 Query: 976 MNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNA 1035 +++L K+ +++ + E+ EI KL + KD+ I L+ +N Sbjct: 3185 NQIDQLKKL--------LEETKQNDDKLVEELTKEIEKLKNEQQSKDQNINDLSA-LNKD 3235 Query: 1036 QVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKEL 1095 + S + D K +F +N + ++ + KQ +S Q N L+I E I +L Sbjct: 3236 KSSLIQQNDDLSKKTQEFYNSQQNQAQMIEDLKKQN-ESLQKN--LEINNNETQQNIDQL 3292 Query: 1096 KETKLTFEMNIPKTEGMI--ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQE 1153 + K + E I ++S I+ +++ ++ +++ + I + Sbjct: 3293 TKDKSDLASKLHDYEAKINDLNSLIKELNEKNAIIEKKNYEFSQ-----QLEVNNDLISK 3347 Query: 1154 RSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNL 1213 + LQ+ +LN + +I L N E+T + I + K K ++LN NL Sbjct: 3348 NNQLQQTIDQLNKDKTVLSKQIQDLANKNNEITNQLNNKDKIILESKQKSDELNQSLSNL 3407 Query: 1214 LSTVA-------ELRSSIS-SAVDQRGFEIA-ELWKQHLAQREADFQKTEHELRVQLSAF 1264 + + +L S IS S ++ ++ E K+ L + + K +L ++ Sbjct: 3408 MKELHTLKANNDDLNSQISQSKQNEENLQLQIEKQKKLLQDTKQNDNKLVDDLSKEVETL 3467 Query: 1265 ESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEH-LRNLQEKYADVINQIEIL 1323 S+ + + ++ + + + + ++Q NK +++ +H L ++K ++N + Sbjct: 3468 TSEKLKNEEIIKQNNAKYSGILKQLQQKNEEINKEKEQFKHDLEGEKQKNEKLVNDLNQT 3527 Query: 1324 RSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXX 1383 + ++ E D + ++++ +Q+ +Q I ++ + + +K Sbjct: 3528 KDKLSQENEKLKHYLVAFKQNNEQITADNKQKDENIQQLMKQ-INSLKSQLQEDEKLKSQ 3586 Query: 1384 XXXXXXXXXXRVNDAEAKVLELTHQLE--LKDSEIYQKTHEYTITLTQRNDEFENVRQQL 1441 +N + LTH L LK +E K +E L Q N+ N QL Sbjct: 3587 FAKMKENYDSLINKLNQENKSLTHSLNESLKHNEELSKNNE---KLQQNNELLSNKLNQL 3643 Query: 1442 VEYE----KRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITE 1497 + K IE++ + + + K + + K S IE + E++N ++E Sbjct: 3644 GSQDNNKQKEIENMNQKLQKVSNEGKQKEDQLIEEINNL-KFSLIELQRKNEDMNQMLSE 3702 Query: 1498 SVSLNKQVAELNKALE------EEVAKT--NEMQTALENQEIEIVTLNDEITNLQNMVRA 1549 + N+ ++E N ++ E ++K+ +E+ + E E +I DEI +L+ Sbjct: 3703 TKKQNEVLSEQNNEIQLLKNELENLSKSKEDEINSLKEEYERKIKEKEDEIEHLEENCNN 3762 Query: 1550 SSSKIQKHVSFASDTKQGRDEQLDNT 1575 K + + + K + + NT Sbjct: 3763 EKKKTESYEKKFVEEKGEYESKQQNT 3788 Score = 161 bits (392), Expect = 1e-37 Identities = 289/1458 (19%), Positives = 613/1458 (42%), Gaps = 139/1458 (9%) Query: 144 VTHLSNTIKEKDNALSVLQVKMKIMETTILDLQE-----KINEKDQIIEAKNKATTXXXX 198 + L+ + E + L+ + KM + +LQ+ K N+ D I + + + Sbjct: 2520 IDQLNQDLSESKSKLNDYETKMNELNLLNKELQKDNETLKENQSDLINQIEELSKKNENL 2579 Query: 199 XXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANK 258 D QQ+ + +++ E +RL K+ + ++ SL++ + Sbjct: 2580 INLQGTNSNLVLKNDELQQLI---DKLNKEKSDLIQENERLTKNNGESNEKLQSLDQMIE 2636 Query: 259 LLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXX---LAKQSIEPSCEEKTEIEEKGS 315 ++ E E+ ++ +L + + K S++ ++ E++ Sbjct: 2637 TVKNNSSEKDKENHQIIDQLNKEKLDLSSKLKDYENQLDVLKSSLKELNDKNKELQNGND 2696 Query: 316 LEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSS-PSKKGSPLISR-K 373 + LT KI LE N ++ TN+ + ++ + + +S S+ S L SR K Sbjct: 2697 ILKQENETLTPKISSLESENSSLKSTNEIKDKEIEELKQKLSEISQLNSQHESDLDSRRK 2756 Query: 374 SGRNTASKMKSPWSQLSSET-LNQDTDKKI-NKNE--IAKLEMVIQSLNKDLVDKEYVIS 429 ++++ +L +E + + K++ N+NE + LE + LN ++KE+ Sbjct: 2757 QFEKELEELRNQLEKLQNEIQIREQRGKELSNQNEELMNNLEKMKSELNDAKMNKEHSDQ 2816 Query: 430 EKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQ-- 487 E +T D L+ +L E ++ ++ L + +EI ++Q +++ Sbjct: 2817 ENETLKKSLEENQQNYDQLVDELSKEIEE-LKKQLLTKAEESNSSKHEIDELQSKIQNLS 2875 Query: 488 ELNDEIKDVN--VKDLIEKLKS----AEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQ 541 N+ +K N +K IE LK+ ++ + +L EID++NK ++N L KQ+ Sbjct: 2876 SENENLKSTNNELKQQIESLKNDLQNKDQIVEELTKEIDSSNKQ--SHENNELLNQKQLD 2933 Query: 542 --KTIDNFSKVS-DSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDV 598 K I++ +K + K+ ++ L K EL +E GN + +++ + + + Sbjct: 2934 LMKQIEDLTKKQGEMLKQNQNQENIINDLKIKNEELTKE-GNNKDKVIN-ELNKSLND-- 2989 Query: 599 YKKMIE-MENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCS 657 +K +I+ + N E A+ + DL Q+L+ QQ + +++ + + + + Sbjct: 2990 FKSLIQNLSNENEKLKSALQNSQGNNADLQQKLNSTQQNDQNLLNQIELLKKSLQENKQN 3049 Query: 658 EIKSVHLEEQIDALSASKKELALVIENLKLDKEQL---YGTIKDLEN-DKEDIMNKLQNY 713 E V+ E Q + K+ +IE+L+ E+L I+D N +K +++KLQ Sbjct: 3050 EDNLVN-EIQNQKIENQNKDQ--IIEDLRKKNEELNLKQQQIQDQFNKEKSGLISKLQGL 3106 Query: 714 IQENMDLTDKLEKMSAEKISELLAKINH-EEQSKIQTQFGIDAKIQERDLYIENIESELS 772 +L EK+ E+ S+L+ +IN ++++I Q + + I+ + ++ Sbjct: 3107 NLSGNELLSNNEKLEQEQ-SDLMNQINDLRKKNEILNQ-----QQANNNQIIKECQEKIQ 3160 Query: 773 KYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMD 832 Y+ L+ + + + + + DQL L+E ++ + +EL + L + Sbjct: 3161 NYEESNNELQRKLNEAMNNNENAKNQIDQLKKLLEETKQNDDKLV---EELTKEIEKLKN 3217 Query: 833 HDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESE 892 + ++ + ++ NK+ L+++N +L Q+ YN+ +A + + + Sbjct: 3218 EQQSKDQNINDLSALNKDKSS----LIQQNDDLS---KKTQEFYNSQQNQAQMIEDLKKQ 3270 Query: 893 STKYQTQLR----DLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNE 948 + Q L + + N+ ++T + L K + E + N+ I+ + +K + E Sbjct: 3271 NESLQKNLEINNNETQQNIDQLTKDKSDL-ASKLHDYEAKINDLNSLIKE-LNEKNAIIE 3328 Query: 949 KYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYI 1008 K KN E+ QLE N L +++LNK + ++ K +Q ++ + T Q + Sbjct: 3329 K--KNYEFSQQLEVNNDLISKN-NQLQQTIDQLNK-DKTVLSKQIQDLANKNNEITNQ-L 3383 Query: 1009 NEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVS---DYESKLAQFTTKLENMEEEMQ 1065 N +K+ KQK +E LNQ ++N ++ + D S+++Q EN++ +++ Sbjct: 3384 NNKDKIILESKQKSDE---LNQSLSNLMKELHTLKANNDDLNSQISQSKQNEENLQLQIE 3440 Query: 1066 RVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDA 1125 + K L D+KQ++ +L V + +++ L KL E I K S ++ + Sbjct: 3441 KQKKLLQDTKQNDNKL---VDDLSKEVETLTSEKLKNE-EIIKQNNAKYSGILKQLQQKN 3496 Query: 1126 NNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTEL 1185 ++ K Q+ E+ + + L + KL+ E ++ ++ + N ++ Sbjct: 3497 EEINKEKEQFKHDLEGEK-QKNEKLVND---LNQTKDKLSQENEKLKHYLVAFKQNNEQI 3552 Query: 1186 TGHDVVNQEQINQLKSKLEQLNT---ENDNLLSTVAELRSSISSAVD---QRGFEIAELW 1239 T + E I QL ++ L + E++ L S A+++ + S ++ Q + Sbjct: 3553 TADNKQKDENIQQLMKQINSLKSQLQEDEKLKSQFAKMKENYDSLINKLNQENKSLTHSL 3612 Query: 1240 KQHLAQREADFQKTEHELRVQLSAFESKYEQL----------LDSVQSSTQEETNK---- 1285 + L E + K +L+ +K QL ++++ Q+ +N+ Sbjct: 3613 NESLKHNE-ELSKNNEKLQQNNELLSNKLNQLGSQDNNKQKEIENMNQKLQKVSNEGKQK 3671 Query: 1286 -IVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXX 1344 +E++ +L+ L + + ++ + ++ Q E+L SE +E Sbjct: 3672 EDQLIEEINNLKFSLIELQRKNEDMNQMLSETKKQNEVL-SEQNNEIQLLKNELENLSKS 3730 Query: 1345 XXXXXXDLRTENQSYKQMQEQSILNINEE-NAQLKKSSXXXXXXXXXXX---XRVNDAEA 1400 L+ E + + +E I ++ E N + KK+ + + E Sbjct: 3731 KEDEINSLKEEYERKIKEKEDEIEHLEENCNNEKKKTESYEKKFVEEKGEYESKQQNTET 3790 Query: 1401 KVLELTHQLEL--KDSEIYQKT--------HEYT------ITLTQRNDEFENVRQQLVEY 1444 + EL ++EL K++E KT HEY L + +D F Q +V+ Sbjct: 3791 YIEELETEIELLLKENEQLDKTKYDYDAIQHEYNKVREDLAKLQKEHDNFVEEHQLVVDQ 3850 Query: 1445 EKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQ 1504 K E+L + L+ E A+ E + E EI + K E +KI E + Q Sbjct: 3851 LKNHEEL-------IGFLKQDKEEIASKLEAQEDEIEIMKTK-ANESEMKIEEYENSQDQ 3902 Query: 1505 VAELNKALEEEVAKTNEM 1522 + EEE ++ ++ Sbjct: 3903 I---RSKYEEEANESKKL 3917 Score = 116 bits (278), Expect = 7e-24 Identities = 193/1001 (19%), Positives = 428/1001 (42%), Gaps = 82/1001 (8%) Query: 619 LESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKEL 678 + S+K + L +Q+ Y+ + +K ++ S + + + L LS + Sbjct: 1 MSSEKGSESKSLDEIQRIYNRLVEKYSESSSILKSPIKGNQNATQLNSSSLILSQERVNP 60 Query: 679 ALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAK 738 A V + + + T++ + N K+ +++ + + A K+++ L + Sbjct: 61 ANVSKKYRAFFKDYISTLETI-NQSLTANPKITKSVKQQI--------VKARKLAKHLRE 111 Query: 739 INHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVME-DRRYSLER 797 +N+EE Q + + + ++I+N ++ + Y+ + D L Sbjct: 112 LNYEEDISESIQDTSLNEDRVKRVFIDN-QNLMKNYEDDLNHTTPKNPHPNLDDSEVLPD 170 Query: 798 KADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQI 857 D ++ + ++ +E N L L ++ ++ K +N++L K+N+ Sbjct: 171 NMDDSSLIIENVRTRDFKFDPEELNQQNTLDELTQNNEILSK-------DNEKLSKENEQ 223 Query: 858 LLEENQNLQISLSDMQ----QHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHE 913 L +EN +L L + + N + + + ++ + Q +L +L+ +++T Sbjct: 224 LNQENTSLSTLLGSAKSTNLELENTIEQLKSANKELSDKNVEIQAKLINLQKEKEQLTST 283 Query: 914 HQTLIVQK---KKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNN 970 + L+ + KKEI++L +I ++ L+ + + N + + L + + + Sbjct: 284 NDKLLTETENLKKEIDELNNANKELNVKSINLQQSLDNEKQNNKKMIQDLNKEKTDLISK 343 Query: 971 IENLNMNVEE----LNKMNLELIDKHVQKQQTQSP-DYTEQYINEINKLNALLKQKDEEI 1025 IE L M+ +E LN +N D + Q Q+ + E+ I ++ K N L ++ Sbjct: 344 IEKLEMDNKEMNSKLNNVNTSYNDLDAKNQNNQTKVNNLEKIIEKLIKENTELANNNKNN 403 Query: 1026 IALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSK--QLLDSKQHNEELQI 1083 + ++ N +S +D +K TK++ + +E + + ++L S + + Sbjct: 404 NSKIDELQNQNKDLISASNDMNTKNQSLQTKIDQLNKEKTELEEKNKVLKSNLEGLKSDL 463 Query: 1084 LVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIE---PMSDDANNVDXXXXXXXXXXX 1140 L + Q+ K K+ ++ + E ++SS +E ++DD N Sbjct: 464 LSKNQESTKKNENLQKIIDQL---QNENKLLSSNLENQTKLNDDLNKEKSDLQS------ 514 Query: 1141 XLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTG--------HDVVN 1192 K++E E+ ++ + E + K ++E KI L+ N ELT +D +N Sbjct: 515 --KIEELEKNNKDLTSNLENNHK---TIEELSNKINDLQNNNKELTSNLEDQNKLNDDLN 569 Query: 1193 QEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQ-HLAQREADFQ 1251 +E+ + L+SK+E+L+T+N+ L S+ + ++ + VD+ I +L K+ + + Sbjct: 570 KEKAD-LQSKIEELSTKNEELESSNKNEKENLQNKVDEFEKIIDQLRKEKEVLEENEKVS 628 Query: 1252 KT----EHELRVQLSAFESKYEQLLDSVQSSTQE-ETNKIVTMEQVTSLQNKLQDKEEHL 1306 KT ++++ +L+ +S + +D ++ + ++ TN ++ ++ + L + ++K + + Sbjct: 629 KTNIDDDYKVIEELNNEKSDLQSKIDQLEKNNKDLTTNLELSNKEKSDLSLENENKRKEI 688 Query: 1307 RNLQEKYADVINQIEILRSEIED-EKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQ 1365 L+ N IE L+ +I++ EK EN +E Sbjct: 689 DELKSLNNKTNNDIEKLQLQIQELEKSNEQLQKEKEVLSSENNQLKSNVENSE----KEI 744 Query: 1366 SILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTH-QLELKDSEIYQKTHEYT 1424 ILN + + Q K + KVL + L+ K E+ K E Sbjct: 745 GILNKEKADLQSKVEELDNNNKELASNLENQNKLNKVLNNENSDLQSKIEELTTKNQELE 804 Query: 1425 ITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIER 1484 + + N+E EN++ ++ E EK I++L +KE+E + +NH T + +E Sbjct: 805 SSNIETNNEKENLQARINELEKIIDEL--QKENE------NLETESNHLRTDLQNNEKTI 856 Query: 1485 VKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEI-VTLNDEITNL 1543 L ++ N ++ L K E +++ A ++QT +N E++ V L ++I + Sbjct: 857 ADLNKDKNDLTSKIGELEKNNKEFTTLIDKINASNKDLQT--KNDELQSKVDLLEKILDQ 914 Query: 1544 QNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAV 1584 N ++ + + + D + +E L N NK+L + + Sbjct: 915 LNKDKSDLITKLEELQTSIDQMKQTNENL-NKENKDLQNKI 954 Score = 109 bits (263), Expect = 5e-22 Identities = 173/812 (21%), Positives = 343/812 (42%), Gaps = 94/812 (11%) Query: 804 SYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQ 863 +Y ++ ++ + ++ ED V R V +D+ +++ ++ H + N L++++ Sbjct: 113 NYEEDISESIQDTSLNEDR-VKR--VFIDNQNLMKNYEDDLNHTTPKNPHPN---LDDSE 166 Query: 864 NLQISLSDMQQHYNALVEKANRTDLA-ESESTKYQTQLRDLESNLKRITHEHQTLIVQKK 922 L ++ D + ++E D + E Q L +L N + ++ +++ L Sbjct: 167 VLPDNMDDS----SLIIENVRTRDFKFDPEELNQQNTLDELTQNNEILSKDNEKL----S 218 Query: 923 KEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELN 982 KE E L E NT + + + K N + E IE + +L + I+ +N+++ Sbjct: 219 KENEQLNQE-NTSLSTLLGSAKSTNLELENTIEQLKSANKELSDKNVEIQAKLINLQKEK 277 Query: 983 KMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSM 1042 + DK + + TE EI++LN K+ + + I L Q ++N + + M Sbjct: 278 EQLTSTNDKLLTE--------TENLKKEIDELNNANKELNVKSINLQQSLDNEKQNNKKM 329 Query: 1043 VSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTF 1102 + D + +K+E +E +D+K+ N +L + +D + + T Sbjct: 330 IQDLNKEKTDLISKIEKLE----------MDNKEMNSKLNNVNTSYND-LDAKNQNNQTK 378 Query: 1103 EMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSA 1162 N+ K +I E +++ NN K+ E + Q + ++ S Sbjct: 379 VNNLEKIIEKLIKENTELANNNKNNNS-------------KIDELQN--QNKDLISA-SN 422 Query: 1163 KLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRS 1222 +NT+ Q TKI QL TEL + V + + LKS L N E+ + Sbjct: 423 DMNTKNQSLQTKIDQLNKEKTELEEKNKVLKSNLEGLKSDLLSKNQES-------TKKNE 475 Query: 1223 SISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEE 1282 ++ +DQ E + L+ + K +L + S +SK E+L + + T Sbjct: 476 NLQKIIDQLQNE-----NKLLSSNLENQTKLNDDLNKEKSDLQSKIEELEKNNKDLTSNL 530 Query: 1283 TNKIVTMEQVTSLQNKLQDKEEHLR-NL--QEKYADVINQIEI-LRSEIEDEKVAFXXXX 1338 N T+E++++ N LQ+ + L NL Q K D +N+ + L+S+IE+ Sbjct: 531 ENNHKTIEELSNKINDLQNNNKELTSNLEDQNKLNDDLNKEKADLQSKIEE--------- 581 Query: 1339 XXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDA 1398 +L + N++ K+ + + + QL+K ++D Sbjct: 582 ------LSTKNEELESSNKNEKENLQNKVDEFEKIIDQLRKEKEVLEENEKVSKTNIDDD 635 Query: 1399 EAKVLELTHQ---LELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDL---T 1452 + EL ++ L+ K ++ + + T L N E ++ + K I++L Sbjct: 636 YKVIEELNNEKSDLQSKIDQLEKNNKDLTTNLELSNKEKSDLSLENENKRKEIDELKSLN 695 Query: 1453 YEKESELAILRLKMHENANHYETMQKESEI---ERVKLIEELNVKITESVSLNKQVAELN 1509 + +++ L+L++ E E +QKE E+ E +L + E LNK+ A+L Sbjct: 696 NKTNNDIEKLQLQIQELEKSNEQLQKEKEVLSSENNQLKSNVENSEKEIGILNKEKADLQ 755 Query: 1510 KALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRD 1569 +EE E+ + LENQ LN+E ++LQ+ + ++K Q+ S +T + Sbjct: 756 SKVEELDNNNKELASNLENQNKLNKVLNNENSDLQSKIEELTTKNQELESSNIETNNEK- 814 Query: 1570 EQLDNTMN--KELLDAVPRAELDLAMYMLHQR 1599 E L +N ++++D + + +L H R Sbjct: 815 ENLQARINELEKIIDELQKENENLETESNHLR 846 >UniRef50_A2E8Z5 Cluster: Viral A-type inclusion protein, putative; n=1; Trichomonas vaginalis G3|Rep: Viral A-type inclusion protein, putative - Trichomonas vaginalis G3 Length = 4057 Score = 209 bits (510), Expect = 6e-52 Identities = 282/1336 (21%), Positives = 599/1336 (44%), Gaps = 142/1336 (10%) Query: 309 EIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSP 368 E++EK + N E + I L+ N Q+ NK L++++ ++ T+ + V KK Sbjct: 2294 EMDEKVTTNETNSNEKERLISNLQKQNKQLENENKTLQSEIKSLQTD-EFVKDQMKKQLN 2352 Query: 369 LISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLN---KDLVDKE 425 +K SK++ QL +E D K + K E +IQ LN +DL + + Sbjct: 2353 DYEQK-----VSKLEDEKRQLQNEMTKYKDDNSTMKKVLTKQEKIIQKLNTKVEDLTETK 2407 Query: 426 YVI--SEKDTXXXXXXXXXXGKDTL--IAQLQLEHQQHMEG--PSLIHVG----TNTEDV 475 + ++ + K+ L + + LE ++ ++G S+ V + E++ Sbjct: 2408 QTMKQTQSEELSSLEEENEQKKEELKHLKEEFLEKEKRLKGLEKSIQKVTEKITSQKEEI 2467 Query: 476 NEIAK---VQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNM---IKV 529 + K + + EL I + N K+L E L+ ++ + + +++ + ++N+ +K Sbjct: 2468 ENLRKQKLIDDNTISELKSSISE-NEKEL-ENLRKSDSDKSDIIEQLKSESENLSMSLKS 2525 Query: 530 KSNHKLKLKQMQKTIDNFS-KVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQ-LHLVD 587 +SN++ +L ++Q I + ++SD ++ L L +KV E EE+ Q L+ Sbjct: 2526 RSNYENELTKLQNKIQKLNDQISDKEDDLKSKEILLEKLQKKVQETEEKFSETQKLNKTM 2585 Query: 588 YDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKY----DEVEDK 643 D I + + + ++ME ++T K I L +L +++ IL+ K D+ ++K Sbjct: 2586 KDENANISNQL--RALQMELNSKT--KQIEKLVKDNTNLKEKVTILEFKQSNFDDDNKEK 2641 Query: 644 LADISQLQSDQ-------VCSEIKSVHLEE---QIDALSASKKELALVIEN----LKLDK 689 I L++D + +E ++E QI L+ KE ++N LK Sbjct: 2642 EEKIENLENDNFNLKKQIILNEEYKKQIDELKFQISQLNYDNKEKVTRLQNENTLLKTKS 2701 Query: 690 EQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQT 749 Q + ++ ++ED+ ++++ ++ DL K + ++ E+ + + KI Sbjct: 2702 LQNKSELNTVKKEREDLQSEIEE-LKMKFDLEQKENENLKKQNKEIKNQFETTKSEKIYL 2760 Query: 750 QFGI-DAKIQERDLYIEN--IESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYL 806 + I +AK + DL +N +ESEL K + I RL S + D + L + ++ Sbjct: 2761 EKDISNAKTELNDLLDKNNKLESELRKKEREITRLSYSENKLNDLQIELNKLKSEMKDKT 2820 Query: 807 QEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQ---LLEIEHENKELQKKNQILLE-EN 862 E ++ +E +++ +E+ + ++ ++ + + +E+E K++QK+N+ + + EN Sbjct: 2821 SEIERLSNELSLKSEEIYSFSCSSNSFEKEIQTKSDKIKSLENEIKKVQKENEQIKDLEN 2880 Query: 863 Q---------NLQISLSDMQQHYNALVEKAN------RTDLA-----ESESTKYQTQLRD 902 Q NLQ + + ++ N + DL+ + E+ K Q + Sbjct: 2881 QLNEKSLIIENLQKEFKQKDEKHETVLNSMNDKMKGLQNDLSVLSDLQRENEKITKQNEE 2940 Query: 903 LESNLKRITHEHQTLIVQKKKEIEDLE---IEFNTQIESAIRDKKVLNEKYEKNIEYV-T 958 ++S K++ E+ + KK L+ IE NT ++ ++ K+ YE +E T Sbjct: 2941 IKSQNKKLKEENDDKNREIKKLSNTLQKGDIEMNT-LKDLLQTKEEKIRNYEDILEKTKT 2999 Query: 959 QLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKL---N 1015 Q+E + E+ +++ N + +L K LE D + +S + ++ ++I L N Sbjct: 3000 QMEDKNYEFSKTVKDQNDKINQLEK-ELEQRDLELDDLTNKSKSFDDEKNDKIQSLTTEN 3058 Query: 1016 ALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKL----ENMEEEMQRVSKQL 1071 LK+++ + + + + + + ES+L ++ L E E E+ ++ K++ Sbjct: 3059 KNLKKENRTLKGIINSVKKSSNELEERIRNLESQLKSHSSSLIELQEKKETEISKLQKEI 3118 Query: 1072 LDS----KQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANN 1127 + K NE+L +E + +E++E K + + E I E + + + Sbjct: 3119 DEREEKIKSQNEKLSNCRKEVEKTKQEIEEMKAKLNSQLTE-EIQTIKGEKEDLLEKIKS 3177 Query: 1128 VDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTG 1187 ++ LK + ++ + +SV++E+ KL E+ + Q+++L E+ Sbjct: 3178 INKERDELSQQIKSLKRENDDLQQKLKSVIEERE-KLEKEVNDLTQ---QIKSLKNEIEE 3233 Query: 1188 HDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAE--LWKQHLAQ 1245 ++++I KL+ N E L + +L+ + S ++R E L + L Sbjct: 3234 QKEKSKKEIENFSEKLKSSNEEKQKLQNQNDDLQQKLESIKEERENLKRENDLINKKLKS 3293 Query: 1246 READFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEH 1305 + + QK E+ S +S E ++ +ST E+ NK + +Q+ L K+ D Sbjct: 3294 QSEELQKLNKEIDYSKSQIDSLDE--VNKKLNSTNEQENKQLN-DQINKLTTKVNDLNNE 3350 Query: 1306 LRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQ 1365 ++ L + D+I+Q + L ++ + F + + N+ K+ +E+ Sbjct: 3351 IKKLTSEKNDLIDQNKRLNEDLSKKVNQFDE--------------ETQKLNEQLKRSKEE 3396 Query: 1366 SILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTI 1425 I +IN +N +L + ++N K+ LT++ + + + E + Sbjct: 3397 -INDINNQNKKLDSLNNDLKQENN----KLNHEITKLNSLTNEFN-EQKKKFDSVKEENL 3450 Query: 1426 TLTQRNDEF----ENVRQQLVEYEKRIEDLTYEK-ESELAILRLKMHENANHYETMQKES 1480 L N+E E + ++L ++I+++T E + ++ +L K++EN ET ++ Sbjct: 3451 RLNSLNNELKQENEEISKKLKSLNEQIKEITNENNQDQIDLLNKKLNEN----ETFTRKL 3506 Query: 1481 EIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEI 1540 ++ L ++L + E+ LNK+V +L++ LEE +K E EN I++ N+ + Sbjct: 3507 NDDKENLAKKLQISNEENKKLNKKVEDLSEELEE--SKQRE-----ENSLIDLQNKNETL 3559 Query: 1541 TNLQNMVRASSSKIQK 1556 NL+ ++ +IQ+ Sbjct: 3560 ENLKTQIKKQKQQIQE 3575 Score = 207 bits (505), Expect = 2e-51 Identities = 280/1420 (19%), Positives = 623/1420 (43%), Gaps = 99/1420 (6%) Query: 216 QQMTKMQENFIAMEAEWKDEKQRLLK-----DIESKDVRISSLEEANKL---LEAARFEI 267 Q++ EN + + K E L K D+++K L + N L L+ Sbjct: 2007 QKIINESENLQFLVSTLKTENNTLKKVTQDNDLQNKKTNEDLLSQINDLQNKLKETEKSS 2066 Query: 268 SLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKK 327 ++ SK +L + L ++ E ++EK +L KK Sbjct: 2067 QIQKSKYESQLNEIQSKLNQSIKDNSDL----MDKHENELKNLDEKLQESQKQKNDLEKK 2122 Query: 328 IELLEHLNCQIRQTNKELENKL-ATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPW 386 E+ L + + NK + K T+ + S K + + +N + + + Sbjct: 2123 FEMNSKL---LNENNKLRQEKFDKTLEELTNVKSENGKLKEQIDDLEKEKNEMTILLNTT 2179 Query: 387 SQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKD 446 +E L Q+ KK+N I +L+M N E + + D D Sbjct: 2180 QNNQNEDL-QNLQKKLNAT-IDELKMTTNDYNSLKEKFEKLNGKSDNDNSLISSLKREND 2237 Query: 447 TLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELND-EIKDVNVKDLIEKL 505 + LQ +++ ++ + N + ++++ K +++ ++L E ++ +K + ++ Sbjct: 2238 KMKNDLQKTQEENKS--LVLKLNENEKTISKLQKTNDEISRKLTFVETENGELKLTVNEM 2295 Query: 506 KSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIV-RLTEEL 564 +E++T N+ + +I +L+ KT+ + K +++ + ++ ++L Sbjct: 2296 ---DEKVTT-NETNSNEKERLISNLQKQNKQLENENKTLQSEIKSLQTDEFVKDQMKKQL 2351 Query: 565 HHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAIS-LLESQK 623 + QKV++LE+EK LQ + Y V K ++ T+++ ++ ++ K Sbjct: 2352 NDYEQKVSKLEDEKRQLQNEMTKYKDDNSTMKKVLTKQEKIIQKLNTKVEDLTETKQTMK 2411 Query: 624 FDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIE 683 +EL L++ E E K ++ L+ + + E + LE+ I ++ IE Sbjct: 2412 QTQSEELSSLEE---ENEQKKEELKHLKEEFLEKEKRLKGLEKSIQKVTEKITSQKEEIE 2468 Query: 684 NLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKIS---ELLAKIN 740 NL+ K TI +L++ + +L+N + + D +D +E++ +E + L ++ N Sbjct: 2469 NLRKQKLIDDNTISELKSSISENEKELENLRKSDSDKSDIIEQLKSESENLSMSLKSRSN 2528 Query: 741 HE-EQSKIQTQFG-IDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERK 798 +E E +K+Q + ++ +I +++ +++ E L K + ++ EE + + +++ + Sbjct: 2529 YENELTKLQNKIQKLNDQISDKEDDLKSKEILLEKLQKKVQETEEKFSETQKLNKTMKDE 2588 Query: 799 ADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQIL 858 + + L+ Q + T Q ++LV L + ++E + + +NKE ++K + L Sbjct: 2589 NANISNQLRALQMELNSKTKQIEKLVKDNTNLKEKVTILEFKQSNFDDDNKEKEEKIENL 2648 Query: 859 LEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLI 918 +N NL+ + +++ + E + ++ + T+L++ + LK + ++++ + Sbjct: 2649 ENDNFNLKKQIILNEEYKKQIDELKFQISQLNYDNKEKVTRLQNENTLLKTKSLQNKSEL 2708 Query: 919 VQKKKEIEDLEIEF-NTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQE---YKNNIENL 974 KKE EDL+ E +++ + K+ N K ++N E Q E E + +I N Sbjct: 2709 NTVKKEREDLQSEIEELKMKFDLEQKENENLK-KQNKEIKNQFETTKSEKIYLEKDISNA 2767 Query: 975 NMNVEELNKMNLELIDKHVQKQQTQSP--DYTEQYIN----EINKLNALLKQKDEEIIAL 1028 + +L N +L + ++K++ + Y+E +N E+NKL + +K K EI L Sbjct: 2768 KTELNDLLDKNNKL-ESELRKKEREITRLSYSENKLNDLQIELNKLKSEMKDKTSEIERL 2826 Query: 1029 NQKIN--NAQV-SYMSMVSDYESKLAQFTTKLENMEEEMQRVSK---QLLDSKQHNEELQ 1082 + +++ + ++ S+ + +E ++ + K++++E E+++V K Q+ D + E Sbjct: 2827 SNELSLKSEEIYSFSCSSNSFEKEIQTKSDKIKSLENEIKKVQKENEQIKDLENQLNEKS 2886 Query: 1083 ILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSD-DANNVDXXXXXXXXXXXX 1141 +++ + K+ K+ K +N + + + + +SD N Sbjct: 2887 LIIENLQKEFKQ-KDEKHETVLNSMNDKMKGLQNDLSVLSDLQRENEKITKQNEEIKSQN 2945 Query: 1142 LKVQEE-----EEFIQERSVLQEQSAKLNT---------ELQECYTKII-----QLETLN 1182 K++EE E + + LQ+ ++NT E Y I+ Q+E N Sbjct: 2946 KKLKEENDDKNREIKKLSNTLQKGDIEMNTLKDLLQTKEEKIRNYEDILEKTKTQMEDKN 3005 Query: 1183 TELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQH 1242 E + ++INQL+ +LEQ + E D+L + + + E L K++ Sbjct: 3006 YEFSKTVKDQNDKINQLEKELEQRDLELDDLTNKSKSFDDEKNDKIQSLTTENKNLKKEN 3065 Query: 1243 LAQREA--DFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQ 1300 + +K+ +EL ++ ES+ L S SS E K T +++ LQ ++ Sbjct: 3066 RTLKGIINSVKKSSNELEERIRNLESQ----LKSHSSSLIELQEKKET--EISKLQKEID 3119 Query: 1301 DKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYK 1360 ++EE +++ EK ++ ++E + EIE+ K DL + +S Sbjct: 3120 EREEKIKSQNEKLSNCRKEVEKTKQEIEEMKAKLNSQLTEEIQTIKGEKEDLLEKIKSIN 3179 Query: 1361 QMQE---QSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIY 1417 + ++ Q I ++ EN L++ VND ++ L +++E + + Sbjct: 3180 KERDELSQQIKSLKRENDDLQQKLKSVIEEREKLEKEVNDLTQQIKSLKNEIEEQKEKSK 3239 Query: 1418 QKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKES---ELAILRLKMHENANHYE 1474 ++ ++ L N+E + ++ Q + ++++E + E+E+ E ++ K+ + + Sbjct: 3240 KEIENFSEKLKSSNEEKQKLQNQNDDLQQKLESIKEERENLKRENDLINKKLKSQSEELQ 3299 Query: 1475 TMQKESEIERVKL--IEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIE 1532 + KE + + ++ ++E+N K+ S N+Q NK L +++ N++ T + + E Sbjct: 3300 KLNKEIDYSKSQIDSLDEVNKKLN---STNEQE---NKQLNDQI---NKLTTKVNDLNNE 3350 Query: 1533 IVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQL 1572 I L E +L + + + + K V+ + Q +EQL Sbjct: 3351 IKKLTSEKNDLIDQNKRLNEDLSKKVNQFDEETQKLNEQL 3390 Score = 200 bits (489), Expect = 2e-49 Identities = 296/1501 (19%), Positives = 645/1501 (42%), Gaps = 117/1501 (7%) Query: 148 SNTIKEKDNA-LSVLQVKMKIMETTILDLQEKINEKDQI---IEAKNKATTXXXXXXXXX 203 +N+I ++ NA + +L+ ++ TI DLQ+ INE + + + Sbjct: 1978 NNSIVKQQNAKIEMLKQQLIDQNKTIEDLQKIINESENLQFLVSTLKTENNTLKKVTQDN 2037 Query: 204 XXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRIS-SLEEANKLLEA 262 ED Q+ +Q E + +K + + +++ S+++ + L++ Sbjct: 2038 DLQNKKTNEDLLSQINDLQNKLKETEKSSQIQKSKYESQLNEIQSKLNQSIKDNSDLMDK 2097 Query: 263 ARFEIS------LEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIE-EKGS 315 E+ E K +LE+ L ++ + + EE T ++ E G Sbjct: 2098 HENELKNLDEKLQESQKQKNDLEKKFEMNSKLLNENNKLRQEKFDKTLEELTNVKSENGK 2157 Query: 316 LEIANMTELTK-KIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKS 374 L+ + +L K K E+ LN N++L+N + + + + L + Sbjct: 2158 LK-EQIDDLEKEKNEMTILLNTTQNNQNEDLQNLQKKLNATIDELKMTTNDYNSLKEKFE 2216 Query: 375 GRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTX 434 N K + S +SS L ++ DK KN++ K + +SL L + E IS+ Sbjct: 2217 KLN--GKSDNDNSLISS--LKRENDKM--KNDLQKTQEENKSLVLKLNENEKTISKLQKT 2270 Query: 435 XXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTED--VNEIAKVQEQLKQE---L 489 +T +L+L + E + +N ++ ++ + K +QL+ E L Sbjct: 2271 NDEISRKLTFVETENGELKLTVNEMDEKVTTNETNSNEKERLISNLQKQNKQLENENKTL 2330 Query: 490 NDEIKDVN----VKDLIEK-LKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTI 544 EIK + VKD ++K L E+++++L DE M K K ++ K + K Sbjct: 2331 QSEIKSLQTDEFVKDQMKKQLNDYEQKVSKLEDEKRQLQNEMTKYKDDNSTMKKVLTKQE 2390 Query: 545 DNFSKVSDSNKEIVRLTEELHHL-SQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMI 603 K++ +++ + + S++++ LEEE + L + ++ + +K Sbjct: 2391 KIIQKLNTKVEDLTETKQTMKQTQSEELSSLEEENEQKKEEL------KHLKEEFLEKEK 2444 Query: 604 EMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSV- 662 ++ L ++ K + SQK +E+ L+++ KL D D SE+KS Sbjct: 2445 RLKGLEKSIQKVTEKITSQK----EEIENLRKQ------KLID------DNTISELKSSI 2488 Query: 663 -HLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQE-NMDL 720 E++++ L S + + +IE LK + E L ++K N E+ + KLQN IQ+ N + Sbjct: 2489 SENEKELENLRKSDSDKSDIIEQLKSESENLSMSLKSRSN-YENELTKLQNKIQKLNDQI 2547 Query: 721 TDKLEKMSAEKI--SELLAKINHEEQSKIQTQFGIDAKIQERDLYIEN----IESELSKY 774 +DK + + +++I +L K+ E+ +TQ ++ +++ + I N ++ EL+ Sbjct: 2548 SDKEDDLKSKEILLEKLQKKVQETEEKFSETQ-KLNKTMKDENANISNQLRALQMELNSK 2606 Query: 775 KSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHD 834 +I +L + ++++ LE K +EK++ L ++ + ++ Sbjct: 2607 TKQIEKLVKDNTNLKEKVTILEFKQSNFDDDNKEKEEKIENLENDNFNLKKQIILNEEYK 2666 Query: 835 RVVEK---QLLEIEHENKE----LQKKNQIL----LEENQNLQISLSDMQQHYNALVEKA 883 + +++ Q+ ++ ++NKE LQ +N +L L+ L + + + + E Sbjct: 2667 KQIDELKFQISQLNYDNKEKVTRLQNENTLLKTKSLQNKSELNTVKKEREDLQSEIEELK 2726 Query: 884 NRTDLAESESTKYQTQLRDLESNLKRITHEHQTL---IVQKKKEIEDLEIEFNTQIESAI 940 + DL + E+ + Q +++++ + E L I K E+ DL ++ N ++ES + Sbjct: 2727 MKFDLEQKENENLKKQNKEIKNQFETTKSEKIYLEKDISNAKTELNDL-LDKNNKLESEL 2785 Query: 941 RDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQS 1000 R K+ + + + L+ +L + K+ +++ +E L+ L L + + S Sbjct: 2786 RKKEREITRLSYSENKLNDLQIELNKLKSEMKDKTSEIERLSN-ELSLKSEEIYSFSCSS 2844 Query: 1001 PDYTEQYINEINKLNAL------LKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFT 1054 + ++ + +K+ +L +++++E+I L ++N + ++ +++ K + Sbjct: 2845 NSFEKEIQTKSDKIKSLENEIKKVQKENEQIKDLENQLNEKSLIIENLQKEFKQKDEKHE 2904 Query: 1055 TKLENMEEEMQRVSKQLL---DSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEG 1111 T L +M ++M+ + L D ++ NE++ E Q K+LKE I K Sbjct: 2905 TVLNSMNDKMKGLQNDLSVLSDLQRENEKITKQNEEIKSQNKKLKEENDDKNREIKKLSN 2964 Query: 1112 MIISSTIE--PMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQ 1169 + IE + D + K Q E++ + +++Q+ K+N + Sbjct: 2965 TLQKGDIEMNTLKDLLQTKEEKIRNYEDILEKTKTQMEDKNYEFSKTVKDQNDKINQLEK 3024 Query: 1170 ECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVD 1229 E + ++L+ L + D ++I L ++ + L EN L + ++ S S+ ++ Sbjct: 3025 ELEQRDLELDDLTNKSKSFDDEKNDKIQSLTTENKNLKKENRTLKGIINSVKKS-SNELE 3083 Query: 1230 QRGFEIAELWKQHLA-------QREADFQKTEHELRVQLSAFESKYEQLLD---SVQSST 1279 +R + K H + ++E + K + E+ + +S+ E+L + V+ + Sbjct: 3084 ERIRNLESQLKSHSSSLIELQEKKETEISKLQKEIDEREEKIKSQNEKLSNCRKEVEKTK 3143 Query: 1280 QE------ETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVA 1333 QE + N +T E++ +++ + +D E ++++ ++ ++ QI+ L+ E +D + Sbjct: 3144 QEIEEMKAKLNSQLT-EEIQTIKGEKEDLLEKIKSINKERDELSQQIKSLKRENDDLQQK 3202 Query: 1334 FXXXXXXXXXXXXXXXXDLRTENQSYK-QMQEQSILNINE-ENAQLK-KSSXXXXXXXXX 1390 DL + +S K +++EQ + E EN K KSS Sbjct: 3203 LKSVIEEREKLEKEVN-DLTQQIKSLKNEIEEQKEKSKKEIENFSEKLKSSNEEKQKLQN 3261 Query: 1391 XXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIED 1450 + + E L+ ++ I +K + L + N E + + Q+ ++ + Sbjct: 3262 QNDDLQQKLESIKEERENLKRENDLINKKLKSQSEELQKLNKEIDYSKSQIDSLDEVNKK 3321 Query: 1451 LTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNK 1510 L E E ++++ N T + E KL E N I ++ LN+ +++ Sbjct: 3322 LNSTNEQE----NKQLNDQINKLTTKVNDLNNEIKKLTSEKNDLIDQNKRLNEDLSKKVN 3377 Query: 1511 ALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDE 1570 +EE K NE + + +I N ++ +L N ++ ++K+ ++ + +E Sbjct: 3378 QFDEETQKLNEQLKRSKEEINDINNQNKKLDSLNNDLKQENNKLNHEITKLNSLTNEFNE 3437 Query: 1571 Q 1571 Q Sbjct: 3438 Q 3438 Score = 198 bits (484), Expect = 8e-49 Identities = 316/1501 (21%), Positives = 664/1501 (44%), Gaps = 134/1501 (8%) Query: 140 QLGDVTHLSNTIKEK--DNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXX 197 ++ D+T +K K DN L V++ +++ + DL+EKI EKD I+ + Sbjct: 719 KMKDLTDEMENLKRKLLDNELDVVKDQLQKEKQKSQDLEEKIEEKDSTIQILKEKIN--- 775 Query: 198 XXXXXXXXXXXXXXEDTKQQMTKM---QENFIAMEAEWKDEKQRLLKDI-ESKDVRISSL 253 E++K+ K+ ++ IA+ + +E Q L+K+ ES +ISSL Sbjct: 776 -----------ENLEESKKSYDKLMNDKQEEIALLQKQINELQELIKNNGESSKTKISSL 824 Query: 254 EEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAK--QSIEPSC-EEKTEI 310 + N L +++ + ++ L K Q+++ + K++I Sbjct: 825 LQENTNLNTKIQQLNSLLKQKDDKINDLQNEINDLTQNKIDLEKQIQNLQTIIFDSKSQI 884 Query: 311 EEKGSLEIANMTELTKKI-ELLEHLNCQIRQTNKELE------NKLAT-MGTESKAVSSP 362 E +I+ + +L K E ++ LN +I+QT EL+ KL + E K Sbjct: 885 ESLNE-KISGLQQLLKSSQETIDSLNDKIKQTQIELQESKDFAEKLQNDINEEKKKTEDY 943 Query: 363 SKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLV 422 K + RN + + + ++E + Q DK K+EI +L I LN + Sbjct: 944 QLKLDDIDRLTKERNLLKETEKSLTLTNAENM-QTIDKL--KDEIEQLNDKISQLNTTID 1000 Query: 423 DKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQ 482 VIS+KD + + ++Q+ +E + E++ +I+K Sbjct: 1001 QLNDVISKKDEEIKQDLQKFELSEKVHQAAINDYQKQLEHHE-EQITLLEEEIEKISKEN 1059 Query: 483 EQLKQE-LNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKV---KSNHKLKLK 538 LK + L +E K + D+ ++ + +I QL +E+ N+ K+ N +++++ Sbjct: 1060 SDLKAKILENEAKLDDFDDVSKQNSEYKAKIEQLEEELADYESNLQKLSEENGNLEIQIE 1119 Query: 539 QMQ-KTIDN--FSKVSDSNKEIVRLTEELHHL-------SQKVAELEEEKGNLQLHLVDY 588 +++ KT+ N F+++ N ++ EL L Q +A+ ++E +L ++D Sbjct: 1120 EIKLKTVPNTDFNELRTKNTDLEAQIRELKRLLANDDGNKQVIAQKDKEILSLNQTIIDL 1179 Query: 589 DSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADIS 648 + +D K IEM +T S + +++ ++ +D +++KL +++ Sbjct: 1180 QHNNQLLNDKIKD-IEM---TKTNYPERSFNNDELHQTIEDNNV--SMFD-MQNKL-NLA 1231 Query: 649 QLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMN 708 L+ Q EI+ +L+ ++ +L + +E+ I LK I +L ND + N Sbjct: 1232 NLKLKQSEKEIQ--NLKNELLSLQSENEEMNSTINMLKQSLTSKENEINEL-NDSVTVKN 1288 Query: 709 -KLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENI 767 +++ +++N DK +++ L + + H IQ + I ++ I+N+ Sbjct: 1289 SQIEEILKKNQVKFDKTGN-KEQQLQVLNSSLKHSNDI-IQEK---GKTIDSQNKLIKNL 1343 Query: 768 ESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRL 827 E K + + L+ +++ + + LE+ +L S LQ + + QE EL+ L Sbjct: 1344 EDTKQKLQKQNFDLQNNVSNLTN---DLEKTKRELLS-LQNSKNDNIKQLEQEKELI--L 1397 Query: 828 AVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTD 887 + +++ E+++ + + LQ N I ++N+ +Q +L ++Q+ N L N T Sbjct: 1398 KQKENENKISEEKIKNLTLQISNLQ--NTISQKDNE-IQNNLQNLQKVSNELDFIKNSTK 1454 Query: 888 LAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFN---TQIESAI---- 940 E++ T+ + D+ +NL+++ + +K KE +D E + +Q+E+ Sbjct: 1455 DHENDLTEKE----DVINNLRKLFDDKMKENEKKTKEFQDSLREKDLMISQLENKTMFFD 1510 Query: 941 RDKKVLNEKYEK-NIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQ 999 + K ++K + I+ VT + +L+E +N + N ++EL K N E K +Q + Sbjct: 1511 QQMKSKDDKIDSLQIQNVT-FQGELKEIQNKLINSLKQIDELQKEN-ESFQKELQTRDQN 1568 Query: 1000 SPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLEN 1059 D +Q I +L A + Q +EEI + ++ +NN Q + +++YE++ K++ Sbjct: 1569 LDDSHKQ----IEELQAKIDQYEEEIKSKDENLNNLQ----NKINNYENESKTNNEKIKE 1620 Query: 1060 MEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELK-ETK-LTFEMNIPKTEGMIISST 1117 ME + + Q+ D + + + + ++ ++++L+ E K + ++N + E S Sbjct: 1621 MEGKQKSNELQINDLQNNVSQTENENKQLKSELEKLQTEIKSKSDQLNEIQNESKSQSEQ 1680 Query: 1118 IEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQ 1177 I + + L+ +E E F +E + + +++E KI Q Sbjct: 1681 IVTFQGELKELQNKLTSSLKQIDELQ-KENESFQKELQTRDQNLDDSHKQIEELQAKIDQ 1739 Query: 1178 LETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAE 1237 E E+ D E +N L++K+ E+ + E+ S +I + Sbjct: 1740 YE---EEIKSKD----ENLNNLQNKINNYENESKTNNEKIKEMEGKQKS----NELQIND 1788 Query: 1238 LWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVT-MEQVTSLQ 1296 L + +++Q E + ++ + EL + +SK +Q L+ +Q+ ++ ++ +IVT ++V S Sbjct: 1789 L-QNNVSQTENENKQLKSELEKLQTEIKSKSDQ-LNEIQNESKSQSEQIVTFQDEVKSKD 1846 Query: 1297 NKLQDKEEHLRNLQEKYADVINQIE---ILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLR 1353 KLQ +EE ++ L+ K ++ N + L+ ++ D + Sbjct: 1847 EKLQTQEEQIKELENKLNELENSLRNKGDLQVQLNDREKELNNLKKVNENLVKQVEDLQV 1906 Query: 1354 TENQSYKQMQE--QSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLEL 1411 + QS K++ E + + N+ NA LKK + + + ++ ELT+ Sbjct: 1907 NKEQSDKKLSENDEELTNLRRNNADLKKQNEKLRENKEKNESEIISLQNRLSELTNSHND 1966 Query: 1412 KDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDL-TYEKESE-LAILRLKMHEN 1469 + + +K E + Q+N + E ++QQL++ K IEDL ESE L L + Sbjct: 1967 ELFTVKRKLEENNSIVKQQNAKIEMLKQQLIDQNKTIEDLQKIINESENLQFLVSTLKTE 2026 Query: 1470 ANHYETMQKESEIERVKLIEEL---------NVKITE---SVSLNKQVAELNKALEEEVA 1517 N + + ++++++ K E+L +K TE + +K ++LN+ + Sbjct: 2027 NNTLKKVTQDNDLQNKKTNEDLLSQINDLQNKLKETEKSSQIQKSKYESQLNEIQSKLNQ 2086 Query: 1518 KTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMN 1577 + ++ E E+ L++++ Q K + + ++ + R E+ D T+ Sbjct: 2087 SIKDNSDLMDKHENELKNLDEKLQESQKQKNDLEKKFEMNSKLLNENNKLRQEKFDKTLE 2146 Query: 1578 K 1578 + Sbjct: 2147 E 2147 Score = 180 bits (438), Expect = 3e-43 Identities = 282/1537 (18%), Positives = 638/1537 (41%), Gaps = 93/1537 (6%) Query: 94 LANTLKQKEILMEKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKE 153 L N + Q E +++K EL K T ++ Q + +KE Sbjct: 1635 LQNNVSQTENENKQLKS--ELEKLQ--TEIKSKSDQLNEIQNESKSQSEQIVTFQGELKE 1690 Query: 154 KDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXED 213 N L+ ++ ++ Q+++ +DQ ++ +K E+ Sbjct: 1691 LQNKLTSSLKQIDELQKENESFQKELQTRDQNLDDSHKQIEELQAKIDQYEEEIKSKDEN 1750 Query: 214 TKQQMTKMQENFIAMEAEWKDEKQRLLKDIE-SKDVRISSLEEANKLLEAARFEISLEHS 272 K+ N E++ +EK + ++ + S +++I+ L+ E ++ E Sbjct: 1751 LNNLQNKI--NNYENESKTNNEKIKEMEGKQKSNELQINDLQNNVSQTENENKQLKSELE 1808 Query: 273 KLAQELEQXXXXXXXXXXXXXXLAKQSIE-----PSCEEKTEIEEKGSLEIAN-MTELTK 326 KL E++ ++Q + S +EK + +E+ E+ N + EL Sbjct: 1809 KLQTEIKSKSDQLNEIQNESKSQSEQIVTFQDEVKSKDEKLQTQEEQIKELENKLNELEN 1868 Query: 327 KIELLEHLNCQIRQTNKELENKLATMGTESKAVSS---PSKKGSPLISRKSGRNTASKMK 383 + L Q+ KEL N K V ++ +S T + Sbjct: 1869 SLRNKGDLQVQLNDREKELNNLKKVNENLVKQVEDLQVNKEQSDKKLSENDEELTNLRRN 1928 Query: 384 SPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXX 443 + + +E L ++ +K N++EI L+ + L D+ + + K Sbjct: 1929 NADLKKQNEKLRENKEK--NESEIISLQNRLSELTNSHNDELFTVKRKLEENNSIVKQQN 1986 Query: 444 GKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIE 503 K ++ Q ++ + +E L + +E++ + LK E N+ +K V + ++ Sbjct: 1987 AKIEMLKQQLIDQNKTIE--DLQKIINESENLQFLVST---LKTE-NNTLKKVTQDNDLQ 2040 Query: 504 KLKSAEEQITQLND---EIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRL 560 K+ E+ ++Q+ND ++ K+ KS ++ +L ++Q ++ + D++ + + Sbjct: 2041 NKKTNEDLLSQINDLQNKLKETEKSSQIQKSKYESQLNEIQSKLNQ--SIKDNSDLMDKH 2098 Query: 561 TEELHHLSQKVAELEEEKGNLQLHL-----VDYDSGRMIESDVYKKMIEMENLAET--RL 613 EL +L +K+ E +++K +L+ + ++ ++ + K + E+ N+ +L Sbjct: 2099 ENELKNLDEKLQESQKQKNDLEKKFEMNSKLLNENNKLRQEKFDKTLEELTNVKSENGKL 2158 Query: 614 KA-ISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVH-LEEQIDAL 671 K I LE +K ++ L+ Q +E L D++ + L+E+ + L Sbjct: 2159 KEQIDDLEKEKNEMTILLNTTQNNQNEDLQNLQKKLNATIDELKMTTNDYNSLKEKFEKL 2218 Query: 672 SASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEK 731 + +I +LK + +++ ++ + + + ++ KL EN KL+K + E Sbjct: 2219 NGKSDNDNSLISSLKRENDKMKNDLQKTQEENKSLVLKLN----ENEKTISKLQKTNDE- 2273 Query: 732 ISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDR 791 IS L + E T +D K+ + E +S + + +LE ++ Sbjct: 2274 ISRKLTFVETENGELKLTVNEMDEKVTTNETNSNEKERLISNLQKQNKQLENENKTLQSE 2333 Query: 792 RYSLERKA---DQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHEN 848 SL+ DQ+ L + ++ S+ ++ +L N + D + ++K L + E Sbjct: 2334 IKSLQTDEFVKDQMKKQLNDYEQKVSKLEDEKRQLQNEMTKYKDDNSTMKKVLTKQEKII 2393 Query: 849 KELQKKNQILLEENQNL-QISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNL 907 ++L K + L E Q + Q ++ +K + E + + +L+ LE ++ Sbjct: 2394 QKLNTKVEDLTETKQTMKQTQSEELSSLEEENEQKKEELKHLKEEFLEKEKRLKGLEKSI 2453 Query: 908 KRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQ---- 963 +++T + I +K+EIE+L + ++ I + K + EK +E + + ++ Sbjct: 2454 QKVTEK----ITSQKEEIENLRKQKLID-DNTISELKSSISENEKELENLRKSDSDKSDI 2508 Query: 964 LQEYKNNIENLNMNVEELNKMNLEL--IDKHVQKQQTQSPDYTEQYINEINKLNALLK-- 1019 +++ K+ ENL+M+++ + EL + +QK Q D + ++ L L K Sbjct: 2509 IEQLKSESENLSMSLKSRSNYENELTKLQNKIQKLNDQISDKEDDLKSKEILLEKLQKKV 2568 Query: 1020 QKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNE 1079 Q+ EE + QK+N + +S+ +L +L + ++++++ K + K+ Sbjct: 2569 QETEEKFSETQKLNKTMKDENANISN---QLRALQMELNSKTKQIEKLVKDNTNLKEKVT 2625 Query: 1080 ELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXX 1139 L+ DD KE +E E + + II + D Sbjct: 2626 ILEFKQSNFDDDNKEKEEKIENLENDNFNLKKQIILNEEYKKQIDELKFQISQLNYDNKE 2685 Query: 1140 XXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQ---EQI 1196 ++Q E ++ +S LQ +S +LNT +E ++E L + N+ +Q Sbjct: 2686 KVTRLQNENTLLKTKS-LQNKS-ELNTVKKEREDLQSEIEELKMKFDLEQKENENLKKQN 2743 Query: 1197 NQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTE-H 1255 ++K++ E +E L ++ ++ ++ +D+ +EL K+ + + + + Sbjct: 2744 KEIKNQFETTKSEKIYLEKDISNAKTELNDLLDKNNKLESELRKKEREITRLSYSENKLN 2803 Query: 1256 ELRVQLSAFESKYEQLLDSVQSSTQE---ETNKIVTME-QVTSLQNKLQDKEEHLRNLQE 1311 +L+++L+ +S+ + ++ + E ++ +I + S + ++Q K + +++L+ Sbjct: 2804 DLQIELNKLKSEMKDKTSEIERLSNELSLKSEEIYSFSCSSNSFEKEIQTKSDKIKSLEN 2863 Query: 1312 KYADVIN---QIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQ-SI 1367 + V QI+ L +++ ++ + L + N K +Q S+ Sbjct: 2864 EIKKVQKENEQIKDLENQLNEKSLIIENLQKEFKQKDEKHETVLNSMNDKMKGLQNDLSV 2923 Query: 1368 LN-INEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTIT 1426 L+ + EN ++ K + +D ++ +L++ L+ D E+ + Sbjct: 2924 LSDLQRENEKITKQNEEIKSQNKKLKEENDDKNREIKKLSNTLQKGDIEM----NTLKDL 2979 Query: 1427 LTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERV- 1485 L + ++ N L + + ++ED YE + K+++ E Q++ E++ + Sbjct: 2980 LQTKEEKIRNYEDILEKTKTQMEDKNYEFSKTVKDQNDKINQLEKELE--QRDLELDDLT 3037 Query: 1486 ----KLIEELNVKITESVSLNKQVAELNKALE---EEVAKT-NEMQTALENQEIEIVTLN 1537 +E N KI + NK + + N+ L+ V K+ NE++ + N E ++ + + Sbjct: 3038 NKSKSFDDEKNDKIQSLTTENKNLKKENRTLKGIINSVKKSSNELEERIRNLESQLKSHS 3097 Query: 1538 DEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDN 1574 + LQ SK+QK + + + ++E+L N Sbjct: 3098 SSLIELQEKKETEISKLQKEIDEREEKIKSQNEKLSN 3134 Score = 178 bits (434), Expect = 9e-43 Identities = 293/1516 (19%), Positives = 664/1516 (43%), Gaps = 127/1516 (8%) Query: 143 DVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXX 202 D + + + +++ + L K++ + T +++ +E+ +E +N+ Sbjct: 2378 DNSTMKKVLTKQEKIIQKLNTKVEDLTETKQTMKQTQSEELSSLEEENEQKKEELKHLKE 2437 Query: 203 XXXXXXXXXEDTKQQMTKMQENFIAMEAEWKD-EKQRLLKDIESKDVRISSLEEANKLLE 261 + ++ + K+ E + + E ++ KQ+L+ D +++ SS+ E K LE Sbjct: 2438 EFLEKEKRLKGLEKSIQKVTEKITSQKEEIENLRKQKLIDDNTISELK-SSISENEKELE 2496 Query: 262 AARFEISLEHS---KLAQELEQXXXXXXXXXXXXXXLAK--QSIEPSCEEKTEIEEKGSL 316 R S + +L E E L K I+ ++ ++ E+ Sbjct: 2497 NLRKSDSDKSDIIEQLKSESENLSMSLKSRSNYENELTKLQNKIQKLNDQISDKEDDLKS 2556 Query: 317 EIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGR 376 + + +L KK++ E + ++ NK ++++ A + + +A+ + I + Sbjct: 2557 KEILLEKLQKKVQETEEKFSETQKLNKTMKDENANISNQLRALQMELNSKTKQIEKLVKD 2616 Query: 377 NTASKMKSP---WSQLSSETLNQDTDKKI----NKNEIAKLEMVIQSLNKDLVDK-EYVI 428 NT K K + Q + + N++ ++KI N N K ++++ K +D+ ++ I Sbjct: 2617 NTNLKEKVTILEFKQSNFDDDNKEKEEKIENLENDNFNLKKQIILNEEYKKQIDELKFQI 2676 Query: 429 SEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQE 488 S+ + ++TL+ L+++ + +E + E+ K++ L+Q+ Sbjct: 2677 SQLNYDNKEKVTRLQNENTLLKTKSLQNKSELNTVKKEREDLQSE-IEEL-KMKFDLEQK 2734 Query: 489 LNDEIKDVN--VKDLIEKLKSA----EEQI----TQLNDEIDAANKNMIKVKSNHKL--- 535 N+ +K N +K+ E KS E+ I T+LND +D NK +++ + Sbjct: 2735 ENENLKKQNKEIKNQFETTKSEKIYLEKDISNAKTELNDLLDKNNKLESELRKKEREITR 2794 Query: 536 ------KLKQMQKTIDNF-SKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHL-VD 587 KL +Q ++ S++ D EI RL+ EL S+++ + + + Sbjct: 2795 LSYSENKLNDLQIELNKLKSEMKDKTSEIERLSNELSLKSEEIYSFSCSSNSFEKEIQTK 2854 Query: 588 YDSGRMIESDVYKKMIEMENLA--ETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLA 645 D + +E+++ K E E + E +L SL+ +L +E +K++ V + + Sbjct: 2855 SDKIKSLENEIKKVQKENEQIKDLENQLNEKSLIIE---NLQKEFKQKDEKHETVLNSMN 2911 Query: 646 D-ISQLQSD-QVCSEIKSVH--LEEQIDALSASKKELALVIENLKLDKEQLYGTIK--DL 699 D + LQ+D V S+++ + + +Q + + + K+L ++ + ++L T++ D+ Sbjct: 2912 DKMKGLQNDLSVLSDLQRENEKITKQNEEIKSQNKKLKEENDDKNREIKKLSNTLQKGDI 2971 Query: 700 E-NDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQ 758 E N +D++ + I+ D+ +K + +K E +K ++ KI ++ +++ Sbjct: 2972 EMNTLKDLLQTKEEKIRNYEDILEKTKTQMEDKNYEF-SKTVKDQNDKINQ---LEKELE 3027 Query: 759 ERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTI 818 +RDL ++++ + K KS + I + +L+++ L + +K+ +E Sbjct: 3028 QRDLELDDLTN---KSKSFDDEKNDKIQSLTTENKNLKKENRTLKGIINSVKKSSNEL-- 3082 Query: 819 QEDELVNRLAVLMDHD----RVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQ 874 E+ + N + L H + EK+ EI KE+ ++ + + +N+ L ++++ Sbjct: 3083 -EERIRNLESQLKSHSSSLIELQEKKETEISKLQKEIDEREEKIKSQNEKLSNCRKEVEK 3141 Query: 875 HYNALVE-KANRTDLAESESTKYQTQLRDLESNLKRITHEHQTL---IVQKKKEIEDLEI 930 + E KA E + + DL +K I E L I K+E +DL+ Sbjct: 3142 TKQEIEEMKAKLNSQLTEEIQTIKGEKEDLLEKIKSINKERDELSQQIKSLKRENDDLQQ 3201 Query: 931 EFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELN--KMNLEL 988 + + IE + +K +N+ ++ ++E Q ++ K IEN + ++ N K L+ Sbjct: 3202 KLKSVIEEREKLEKEVNDLTQQIKSLKNEIEEQKEKSKKEIENFSEKLKSSNEEKQKLQN 3261 Query: 989 IDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKIN--NAQVSYMSMVS-- 1044 + +Q++ + E E + +N LK + EE+ LN++I+ +Q+ + V+ Sbjct: 3262 QNDDLQQKLESIKEERENLKRENDLINKKLKSQSEELQKLNKEIDYSKSQIDSLDEVNKK 3321 Query: 1045 -----DYESK-----LAQFTTKLENMEEEMQRVSKQ---LLD-SKQHNEELQILVREQDD 1090 + E+K + + TTK+ ++ E+++++ + L+D +K+ NE+L V + D+ Sbjct: 3322 LNSTNEQENKQLNDQINKLTTKVNDLNNEIKKLTSEKNDLIDQNKRLNEDLSKKVNQFDE 3381 Query: 1091 QIKELKET--KLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEE 1148 + ++L E + E+N + + S + + N ++ Q+++ Sbjct: 3382 ETQKLNEQLKRSKEEINDINNQNKKLDSLNNDLKQENNKLNHEITKLNSLTNEFNEQKKK 3441 Query: 1149 -EFIQERSV-LQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQ- 1205 + ++E ++ L + +L E +E K+ L E+T + NQ+QI+ L KL + Sbjct: 3442 FDSVKEENLRLNSLNNELKQENEEISKKLKSLNEQIKEITNEN--NQDQIDLLNKKLNEN 3499 Query: 1206 ------LNTENDNL---LSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQ---KT 1253 LN + +NL L E ++ V+ E+ E KQ D Q +T Sbjct: 3500 ETFTRKLNDDKENLAKKLQISNEENKKLNKKVEDLSEELEES-KQREENSLIDLQNKNET 3558 Query: 1254 EHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKY 1313 L+ Q+ + + +++ + QE N + ++ QN++++++ + NLQ+ Sbjct: 3559 LENLKTQIKKQKQQIQEINRENNNLKQELENSQI---EIDDFQNQIENQKLKIDNLQKV- 3614 Query: 1314 ADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDL-RTENQSYKQMQE--QSILNI 1370 IN +I++ E+++E + + + E Q+ + +++ ++ +I Sbjct: 3615 --TINNEKIIK-ELKNENLELKSLTSDLQLSLHSSQSEKEKIEKQNDENLRDLQKAKSDI 3671 Query: 1371 NEENAQLKKSS--XXXXXXXXXXXXRVNDAEAKVLELTHQLELKD---SEIYQKTHEYTI 1425 ++ LK +S + N + + T + ++D EI Q E Sbjct: 3672 SDLTKLLKNNSPQASIDNRRKFQISQTNTTDIAAVSGTFSV-MEDPISEEIEQLKDENNK 3730 Query: 1426 TLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERV 1485 + + N+++ + +E EKE+ L +L + E +N + + + V Sbjct: 3731 MKKDLSQKIRNLQKDNEFLKSELEKTKSEKENGLLGTKLSISEISNDNDVYLMKINNDLV 3790 Query: 1486 KLIEELNVKITESVSLNKQVAELNKALEE---EVAKTNEMQTALENQEIEIVTLNDEITN 1542 K EL ++I+ N+++ ++NK ++ E+ + +M+ +E + ++ + E N Sbjct: 3791 KENSELKIRISLLEKENEEMKQINKEKKDRTSEMLREKDMRKRMEEELQKLRRSDKEKNN 3850 Query: 1543 LQNMVRASSSKIQKHV 1558 L ++ Q+ V Sbjct: 3851 LIQRIKRKEETAQEEV 3866 Score = 172 bits (418), Expect = 8e-41 Identities = 265/1302 (20%), Positives = 572/1302 (43%), Gaps = 115/1302 (8%) Query: 334 LNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLIS-RKSGRNTASKMKSPWSQLSSE 392 LN ++ + +K+L++K T + + ++ + +K+ + +KS L S+ Sbjct: 304 LNTKLMEADKKLKSKTKDFETLEQKYNVLLEQFHTINQEKKAAADQVEALKSQIKDLQSK 363 Query: 393 TLNQDTDKKINKNEIAKLEMVIQSLN---KDLVDKEYVISEKDTXXXXXXXXXXGKDTLI 449 + N +D K +NEI KL+ + ++ +D+ K +S+ + ++ Sbjct: 364 SANSSSDFKAKQNEIDKLKQINEAQKNFIEDIQRKYDELSQSNLNSPKERTNPFQQELEN 423 Query: 450 AQLQLEHQ---------QHMEGPSLIH-VGTNTEDVNEIAKVQEQLKQELNDEIKDVNVK 499 + +L+ Q Q+M + I+ + + ++ + + +++E + + + +++ Sbjct: 424 LRRRLQDQDKENKALTDQNMALNNQINFLKSQLQNSRQPLPSTQYMEEENSSNLDESDIQ 483 Query: 500 DLIEK---LKSAEEQITQLNDEI----DAANKN---MIKVKSNHKLKLKQMQKTIDNFSK 549 +++E + E +I +LN+ I +AA K K+K + L + ++ + S+ Sbjct: 484 NMLETNQVISDYENKIKELNETILSLRNAAPKTPDTSAKMKRENSLLKSENEELV---SR 540 Query: 550 VSDSNKEIVRLTEELHHLSQKVAELEEE-KGNLQ--LHLVDYDSGRMIESDVYKKMIEME 606 V+ KE +L ++ L+ ++ +++ G++Q L+++ ++ Y+ + Sbjct: 541 VNQIKKENTQLKSDIQDLNNQLRNKKKDFAGSVQNQLNIIKLFLNKLFADFNYEIQKTKQ 600 Query: 607 NLAETRLKAISLLESQKFD-------LVQELHILQQKYDEVEDKLADI-SQLQSDQVCSE 658 +++ L + L+ QK + L ++++ L+Q+ +++DK+ D+ + LQ +E Sbjct: 601 KISDEFLTILRKLQQQKENETNKTKLLERQINDLKQENMKLKDKINDLQNNLQKILQENE 660 Query: 659 IKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLEND-KEDIMNKLQNYIQEN 717 S + ID LS S KE I K E L IK E D ++ N ++ Q+ Sbjct: 661 NHSKQISTHIDGLSQSIKERDDQILKDKEKIENLQNKIKGKEIDFDQEKSNLIKQNEQKM 720 Query: 718 MDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSR 777 DLTD++E + + + L + + Q + Q ++ KI+E+D I+ ++ ++++ Sbjct: 721 KDLTDEMENLKRKLLDNELDVVKDQLQKEKQKSQDLEEKIEEKDSTIQILKEKINE---- 776 Query: 778 ICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVV 837 LEES ++ D+L + +KQ+ + Q +EL + + + Sbjct: 777 --NLEES-----------KKSYDKL---MNDKQEEIALLQKQINELQELIKNNGESSKTK 820 Query: 838 EKQLL-EIEHENKELQKKNQILLEENQ---NLQISLSDMQQHYNALVEKANRTDLAESES 893 LL E + N ++Q+ N +L +++ +LQ ++D+ Q+ L ++ +S Sbjct: 821 ISSLLQENTNLNTKIQQLNSLLKQKDDKINDLQNEINDLTQNKIDLEKQIQNLQTIIFDS 880 Query: 894 TKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKN 953 L + S L+++ Q I +I+ +IE + A + + +NE+ +K Sbjct: 881 KSQIESLNEKISGLQQLLKSSQETIDSLNDKIKQTQIELQESKDFAEKLQNDINEEKKKT 940 Query: 954 IEYVTQLEA--QLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEI 1011 +Y +L+ +L + +N ++ ++ N N++ IDK ++ + Q D Q I Sbjct: 941 EDYQLKLDDIDRLTKERNLLKETEKSLTLTNAENMQTIDK-LKDEIEQLNDKISQLNTTI 999 Query: 1012 NKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQL 1071 ++LN ++ +KDEEI QK ++ + + ++DY+ +L ++ +EEE++++SK+ Sbjct: 1000 DQLNDVISKKDEEIKQDLQKFELSEKVHQAAINDYQKQLEHHEEQITLLEEEIEKISKEN 1059 Query: 1072 LDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXX 1131 D K E + + + DD K+ E K E + E S ++ +S++ N Sbjct: 1060 SDLKAKILENEAKLDDFDDVSKQNSEYKAKIEQ--LEEELADYESNLQKLSEENGN---- 1113 Query: 1132 XXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVV 1191 L++Q EE I+ ++V +L T+ + +I +L+ L G+ V Sbjct: 1114 ----------LEIQIEE--IKLKTVPNTDFNELRTKNTDLEAQIRELKRLLANDDGNKQV 1161 Query: 1192 ---NQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREA 1248 ++I L + L N L + ++ + + +R F EL Q + Sbjct: 1162 IAQKDKEILSLNQTIIDLQHNNQLLNDKIKDIEMT-KTNYPERSFNNDEL-HQTIEDNNV 1219 Query: 1249 ---DFQKTEHELRVQLSAFESKYEQLLDSVQS--STQEETNKIVTMEQVTSLQNKLQDKE 1303 D Q + ++L E + + L + + S S EE N + M L+ L KE Sbjct: 1220 SMFDMQNKLNLANLKLKQSEKEIQNLKNELLSLQSENEEMNSTINM-----LKQSLTSKE 1274 Query: 1304 EHLRNLQEKYADVINQIE--ILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQ 1361 + L + +QIE + +++++ +K D+ E Sbjct: 1275 NEINELNDSVTVKNSQIEEILKKNQVKFDKTGNKEQQLQVLNSSLKHSNDIIQEKGKTID 1334 Query: 1362 MQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTH 1421 Q + I N+ + +L+K + ND E EL K+ I Q Sbjct: 1335 SQNKLIKNLEDTKQKLQKQNFDLQNNVSNL---TNDLEKTKRELLSLQNSKNDNIKQLEQ 1391 Query: 1422 EYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKES- 1480 E + L Q+ +E + E++I++LT + + + K +E N+ + +QK S Sbjct: 1392 EKELILKQKENENK-------ISEEKIKNLTLQISNLQNTISQKDNEIQNNLQNLQKVSN 1444 Query: 1481 EIERVK-LIEELNVKITESVSLNKQVAEL-NKALEEEVAKTNEMQTALENQEIEIVTLND 1538 E++ +K ++ +TE + + +L + ++E KT E Q +L +++ I L + Sbjct: 1445 ELDFIKNSTKDHENDLTEKEDVINNLRKLFDDKMKENEKKTKEFQDSLREKDLMISQLEN 1504 Query: 1539 EITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKEL 1580 + +++ KI + + T QG +++ N + L Sbjct: 1505 KTMFFDQQMKSKDDKIDS-LQIQNVTFQGELKEIQNKLINSL 1545 Score = 165 bits (402), Expect = 7e-39 Identities = 283/1467 (19%), Positives = 632/1467 (43%), Gaps = 113/1467 (7%) Query: 148 SNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXX 207 S+ K K N + L+ + + I D+Q K D++ ++ + Sbjct: 368 SSDFKAKQNEIDKLKQINEAQKNFIEDIQRKY---DELSQSNLNSPKERTNPFQQELENL 424 Query: 208 XXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEI 267 +D ++ + + +A+ + K +L + EE + L+ + + Sbjct: 425 RRRLQDQDKENKALTDQNMALNNQINFLKSQLQNSRQPLPSTQYMEEENSSNLDESDIQN 484 Query: 268 SLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKK 327 LE +++ + E A ++ + S + K E SL + EL + Sbjct: 485 MLETNQVISDYENKIKELNETILSLRNAAPKTPDTSAKMKRE----NSLLKSENEELVSR 540 Query: 328 IELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWS 387 + ++ N Q++ ++L N+L + L K + +++ Sbjct: 541 VNQIKKENTQLKSDIQDLNNQLRNKKKDFAGSVQNQLNIIKLFLNKLFADFNYEIQKTKQ 600 Query: 388 QLSSETLNQDTDKKINK-NEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKD 446 ++S E L + K NE K +++ + +N DL + + +K ++ Sbjct: 601 KISDEFLTILRKLQQQKENETNKTKLLERQIN-DLKQENMKLKDKINDL---------QN 650 Query: 447 TLIAQLQLEHQQHMEGPSLIHVGTNTEDVNE----IAKVQEQLKQELNDEIKDVNVKDLI 502 L LQ E++ H + S H+ ++ + E I K +E++ + L ++IK + Sbjct: 651 NLQKILQ-ENENHSKQIS-THIDGLSQSIKERDDQILKDKEKI-ENLQNKIKGKEIDFDQ 707 Query: 503 EK---LKSAEEQITQLNDEIDAANKNMIKVKSN-HKLKL-KQMQKTIDNFSKVSDSNKEI 557 EK +K E+++ L DE++ + ++ + + K +L K+ QK+ D K+ + + I Sbjct: 708 EKSNLIKQNEQKMKDLTDEMENLKRKLLDNELDVVKDQLQKEKQKSQDLEEKIEEKDSTI 767 Query: 558 VRLTEELHHLSQKVAELEEEKGNLQLHLVD-YDSGRMIESDVYKKMIEMENLAETRLKAI 616 L E+++ LEE K + + D + +++ + + ++N E+ I Sbjct: 768 QILKEKINE------NLEESKKSYDKLMNDKQEEIALLQKQINELQELIKNNGESSKTKI 821 Query: 617 SLLESQKFDL---VQELH-ILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALS 672 S L + +L +Q+L+ +L+QK D++ D +I+ L +++ E + +L+ + Sbjct: 822 SSLLQENTNLNTKIQQLNSLLKQKDDKINDLQNEINDLTQNKIDLEKQIQNLQ---TIIF 878 Query: 673 ASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEK-MSAEK 731 SK ++ + E + +QL + ++ + D + + Q +QE+ D +KL+ ++ EK Sbjct: 879 DSKSQIESLNEKIS-GLQQLLKSSQETIDSLNDKIKQTQIELQESKDFAEKLQNDINEEK 937 Query: 732 ISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDR 791 ++ ++ ++ + + K E+ L + N E+ I +L++ I + D+ Sbjct: 938 KKTEDYQLKLDDIDRLTKERNL-LKETEKSLTLTNAEN-----MQTIDKLKDEIEQLNDK 991 Query: 792 RYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKEL 851 L DQL + +K + + +Q+ EL ++ +D +KQL E + L Sbjct: 992 ISQLNTTIDQLNDVISKKDEEIKQ-DLQKFELSEKVHQAAIND--YQKQLEHHEEQITLL 1048 Query: 852 QKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRIT 911 +++ + + +EN +L+ + + + + + + + +++ + + +L D ESNL++++ Sbjct: 1049 EEEIEKISKENSDLKAKILENEAKLDDFDDVSKQNSEYKAKIEQLEEELADYESNLQKLS 1108 Query: 912 HEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNI 971 E+ L +Q IE+++++ + NE KN T LEAQ++E K + Sbjct: 1109 EENGNLEIQ----IEEIKLKTVPNTD--------FNELRTKN----TDLEAQIRELKRLL 1152 Query: 972 ENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQK 1031 N + N + + + + E++ + Q + Q +N+ K + K E N + Sbjct: 1153 ANDDGNKQVIAQKDKEILSLN---QTIIDLQHNNQLLNDKIKDIEMTKTNYPERSFNNDE 1209 Query: 1032 INNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQ--ILVREQD 1089 ++ + D ++KL KL+ E+E+Q + +LL + NEE+ I + +Q Sbjct: 1210 LHQTIEDNNVSMFDMQNKLNLANLKLKQSEKEIQNLKNELLSLQSENEEMNSTINMLKQS 1269 Query: 1090 DQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEE 1149 KE + +L + + ++ I + D N + ++ + Sbjct: 1270 LTSKENEINELNDSVTVKNSQIEEILKKNQVKFDKTGNKEQQLQVLNS-----SLKHSND 1324 Query: 1150 FIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQL-NT 1208 IQE+ + KL L++ K L+ N +L + + + K +L L N+ Sbjct: 1325 IIQEKGKTIDSQNKLIKNLEDTKQK---LQKQNFDLQNNVSNLTNDLEKTKRELLSLQNS 1381 Query: 1209 ENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKT----EHELRVQLSAF 1264 +NDN+ E + ++ +I+E ++L + ++ Q T ++E++ L Sbjct: 1382 KNDNIKQLEQEKELILKQKENEN--KISEEKIKNLTLQISNLQNTISQKDNEIQNNLQNL 1439 Query: 1265 ESKYEQLLDSVQSSTQEETNKIVTMEQV-TSLQNKLQDKEEHLRNLQEKYADVINQIEIL 1323 + K LD +++ST++ N + E V +L+ DK + +++ D + + +++ Sbjct: 1440 Q-KVSNELDFIKNSTKDHENDLTEKEDVINNLRKLFDDKMKENEKKTKEFQDSLREKDLM 1498 Query: 1324 RSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXX 1383 S++E++ + F T K++Q + ++N ++ +L+K + Sbjct: 1499 ISQLENKTMFFDQQMKSKDDKIDSLQIQNVTFQGELKEIQNK-LINSLKQIDELQKENES 1557 Query: 1384 XXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVE 1443 ++D+ ++ EL +++ + EI K E L + + +EN + E Sbjct: 1558 FQKELQTRDQNLDDSHKQIEELQAKIDQYEEEIKSK-DENLNNLQNKINNYENESKTNNE 1616 Query: 1444 YEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKL-----IEELNVKITES 1498 K +E +K +EL I L+ + + E Q +SE+E+++ ++LN ES Sbjct: 1617 KIKEMEG--KQKSNELQINDLQNNVSQTENENKQLKSELEKLQTEIKSKSDQLNEIQNES 1674 Query: 1499 VSLNKQVA-------ELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASS 1551 S ++Q+ EL L + + +E+Q E+ + E+ T + + + + Sbjct: 1675 KSQSEQIVTFQGELKELQNKLTSSLKQIDELQKENESFQKELQTRDQNLDDSHKQIEELQ 1734 Query: 1552 SKIQKHVSFASDTKQGRDEQLDNTMNK 1578 +KI ++ + + +DE L+N NK Sbjct: 1735 AKIDQY----EEEIKSKDENLNNLQNK 1757 Score = 163 bits (397), Expect = 3e-38 Identities = 301/1473 (20%), Positives = 613/1473 (41%), Gaps = 135/1473 (9%) Query: 175 LQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQ----ENF----- 225 LQ ++N K + IE K T +D K++ K++ +NF Sbjct: 2599 LQMELNSKTKQIEKLVKDNTNLKEKVTILEFKQSNFDDDNKEKEEKIENLENDNFNLKKQ 2658 Query: 226 IAMEAEWKDEKQRLLKDIESKDV----RISSLEEANKLLEAARFE-------ISLEHSKL 274 I + E+K + L I + +++ L+ N LL+ + + E L Sbjct: 2659 IILNEEYKKQIDELKFQISQLNYDNKEKVTRLQNENTLLKTKSLQNKSELNTVKKEREDL 2718 Query: 275 AQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLE--IANM-TELTKKIELL 331 E+E+ L KQ+ E + +T EK LE I+N TEL ++ Sbjct: 2719 QSEIEELKMKFDLEQKENENLKKQNKEIKNQFETTKSEKIYLEKDISNAKTELNDLLDKN 2778 Query: 332 EHLNCQIRQTNKEL------ENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSP 385 L ++R+ +E+ ENKL + E + S K + I R S + + Sbjct: 2779 NKLESELRKKEREITRLSYSENKLNDLQIELNKLKSEMKDKTSEIERLSNELSLKSEEIY 2838 Query: 386 WSQLSSETLNQDTDKKINKNEIAKLEMV-IQSLNKDLVDKEYVISEKDTXXXXXXXXXXG 444 SS + ++ K +K + + E+ +Q N+ + D E ++EK Sbjct: 2839 SFSCSSNSFEKEIQTKSDKIKSLENEIKKVQKENEQIKDLENQLNEKSLIIENLQKEFKQ 2898 Query: 445 KDTLIAQLQLEHQQHMEG-PSLIHVGTNTEDVNE-IAKVQEQLKQE---LNDEIKDVN-- 497 KD + M+G + + V ++ + NE I K E++K + L +E D N Sbjct: 2899 KDEKHETVLNSMNDKMKGLQNDLSVLSDLQRENEKITKQNEEIKSQNKKLKEENDDKNRE 2958 Query: 498 VKDLIEKLKSAEEQITQLNDEIDAANKN-------MIKVKSNHKLKLKQMQKTI-DNFSK 549 +K L L+ + ++ L D + + + K K+ + K + KT+ D K Sbjct: 2959 IKKLSNTLQKGDIEMNTLKDLLQTKEEKIRNYEDILEKTKTQMEDKNYEFSKTVKDQNDK 3018 Query: 550 VSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMI----EM 605 ++ KE+ + EL L+ K ++EK + L + E+ K +I + Sbjct: 3019 INQLEKELEQRDLELDDLTNKSKSFDDEKNDKIQSLTTENKNLKKENRTLKGIINSVKKS 3078 Query: 606 ENLAETRLKAI-SLLESQKFDLVQ-------ELHILQQKYDEVEDKLADISQLQSD---- 653 N E R++ + S L+S L++ E+ LQ++ DE E+K+ ++ S+ Sbjct: 3079 SNELEERIRNLESQLKSHSSSLIELQEKKETEISKLQKEIDEREEKIKSQNEKLSNCRKE 3138 Query: 654 -----QVCSEIKSV---HLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKED 705 Q E+K+ L E+I + K++L I+++ ++++L IK L+ + +D Sbjct: 3139 VEKTKQEIEEMKAKLNSQLTEEIQTIKGEKEDLLEKIKSINKERDELSQQIKSLKRENDD 3198 Query: 706 IMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIE 765 + KL++ I+E +KLEK + ++ + N E+ K +++ I+ E+ ++ Sbjct: 3199 LQQKLKSVIEER----EKLEKEVNDLTQQIKSLKNEIEEQKEKSKKEIE-NFSEK---LK 3250 Query: 766 NIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVN 825 + E K +++ L++ + +++ R +L+R+ D + L+ + + + + D + Sbjct: 3251 SSNEEKQKLQNQNDDLQQKLESIKEERENLKRENDLINKKLKSQSEELQKLNKEIDYSKS 3310 Query: 826 RLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANR 885 ++ L D V +K E ENK+L + L + +L + + N L+++ R Sbjct: 3311 QIDSL---DEVNKKLNSTNEQENKQLNDQINKLTTKVNDLNNEIKKLTSEKNDLIDQNKR 3367 Query: 886 TDLAESEST-KYQTQLRDLESNLKRITHEHQTLIVQKKKEIE---DLEIEFN------TQ 935 + S+ ++ + + L LKR E + Q KK DL+ E N T+ Sbjct: 3368 LNEDLSKKVNQFDEETQKLNEQLKRSKEEINDINNQNKKLDSLNNDLKQENNKLNHEITK 3427 Query: 936 IESAIRD----KKVLNEKYEKNIEYVT---QLEAQLQEYKNNIENLNMNVEEL-NKMNLE 987 + S + KK + E+N+ + +L+ + +E +++LN ++E+ N+ N + Sbjct: 3428 LNSLTNEFNEQKKKFDSVKEENLRLNSLNNELKQENEEISKKLKSLNEQIKEITNENNQD 3487 Query: 988 LIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYE 1047 ID + K+ ++ +T + ++ L L+ +EE LN+K+ + E Sbjct: 3488 QIDL-LNKKLNENETFTRKLNDDKENLAKKLQISNEENKKLNKKVEDLSEELEESKQREE 3546 Query: 1048 SKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIP 1107 + L K E +E ++ KQ ++ N E L +E ++ E+ + + E Sbjct: 3547 NSLIDLQNKNETLENLKTQIKKQKQQIQEINRENNNLKQELENSQIEIDDFQNQIENQKL 3606 Query: 1108 KTEGM-IISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNT 1166 K + + ++ E + + N + L + + E+ +++Q+ + Sbjct: 3607 KIDNLQKVTINNEKIIKELKN-ENLELKSLTSDLQLSLHSSQ---SEKEKIEKQNDENLR 3662 Query: 1167 ELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLS-TVAELRSSIS 1225 +LQ+ + I L T+L ++ N+ K ++ Q NT + +S T + + IS Sbjct: 3663 DLQKAKSDISDL----TKLLKNNSPQASIDNRRKFQISQTNTTDIAAVSGTFSVMEDPIS 3718 Query: 1226 SAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEET-- 1283 ++Q E ++ K+ L+Q+ + QK L+ +L +S+ E L + S E + Sbjct: 3719 EEIEQLKDENNKM-KKDLSQKIRNLQKDNEFLKSELEKTKSEKENGLLGTKLSISEISND 3777 Query: 1284 ---------NKIVTMEQVTSLQNKLQDKE-EHLRNLQEKYADVINQI---EILRSEIEDE 1330 N +V ++ L +KE E ++ + ++ D +++ + +R +E+E Sbjct: 3778 NDVYLMKINNDLVKENSELKIRISLLEKENEEMKQINKEKKDRTSEMLREKDMRKRMEEE 3837 Query: 1331 KVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSIL---NINEENAQLKKSSXXXXXX 1387 T + ++++E+ I+ +E+NA +K S Sbjct: 3838 LQKLRRSDKEKNNLIQRIKRKEETAQEEVRKVKEEMIILKKVCDEKNAAFEKLSEEHKMI 3897 Query: 1388 XXXXXXRVNDAEAKVLE-LTHQLELKDSE-----IYQK-THEYTITLTQRNDEFENVRQQ 1440 R N++ + E L +LE +E Y K E L + +N + + Sbjct: 3898 LNSLKGRNNESILEENERLKEELENARNESVSNDSYLKINEEVEKNLQTALESLQNAKDE 3957 Query: 1441 LVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVS 1500 K+++ E +S I++ ++ +E + E KL +E + Sbjct: 3958 NERLTKKLQKTERENKSLKQIIKSSEDLKSSEFEEEIDNLKTEVKKLRKEKKSFTNVASK 4017 Query: 1501 LNKQVAELNKALEEEVAKTNEMQTALENQEIEI 1533 + K++ +L K + V N+ + EN EI Sbjct: 4018 MEKKIDKLTKTVTGVVEIVNKYSDSSENPTQEI 4050 Score = 159 bits (386), Expect = 6e-37 Identities = 249/1348 (18%), Positives = 577/1348 (42%), Gaps = 109/1348 (8%) Query: 295 LAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIEL----LEHLNCQIRQTNKELENKLA 350 + KQS+ E E+ + +++ + + E+ KK ++ + Q++ N L++ Sbjct: 1265 MLKQSLTSKENEINELNDSVTVKNSQIEEILKKNQVKFDKTGNKEQQLQVLNSSLKHSND 1324 Query: 351 TMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKL 410 + + K + S +K LI K+ +T K++ L + N D + K E+ L Sbjct: 1325 IIQEKGKTIDSQNK----LI--KNLEDTKQKLQKQNFDLQNNVSNLTNDLEKTKRELLSL 1378 Query: 411 EMVIQSLNKDLV-DKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVG 469 + K L +KE ++ +K+ I+ LQ Q + + + Sbjct: 1379 QNSKNDNIKQLEQEKELILKQKENENKISEEKIKNLTLQISNLQNTISQ--KDNEIQNNL 1436 Query: 470 TNTEDV-NEIAKVQEQLKQELND--EIKDV--NVKDLIE-KLKSAEEQITQLNDEIDAAN 523 N + V NE+ ++ K ND E +DV N++ L + K+K E++ + D + + Sbjct: 1437 QNLQKVSNELDFIKNSTKDHENDLTEKEDVINNLRKLFDDKMKENEKKTKEFQDSLREKD 1496 Query: 524 KNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNK----EIVRLTEELHHLSQKVAELEEEKG 579 + ++++ +QM+ D + N E+ + +L + +++ EL++E Sbjct: 1497 LMISQLENKTMFFDQQMKSKDDKIDSLQIQNVTFQGELKEIQNKLINSLKQIDELQKENE 1556 Query: 580 NLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDE 639 + Q L D D +K++ E++ + + I + +L +++ + + Sbjct: 1557 SFQKELQTRDQNL---DDSHKQIEELQAKIDQYEEEIKSKDENLNNLQNKINNYENESKT 1613 Query: 640 VEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDL 699 +K I +++ Q +E++ L+ + K+L +E L+ + + + ++ Sbjct: 1614 NNEK---IKEMEGKQKSNELQINDLQNNVSQTENENKQLKSELEKLQTEIKSKSDQLNEI 1670 Query: 700 ENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQE 759 +N+ + ++ + E +L +KL S ++I EL K N Q ++QT+ D + + Sbjct: 1671 QNESKSQSEQIVTFQGELKELQNKLTS-SLKQIDEL-QKENESFQKELQTR---DQNLDD 1725 Query: 760 RDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQ 819 IE +++++ +Y+ I +E++ ++++ + E ++ ++E + +Q Sbjct: 1726 SHKQIEELQAKIDQYEEEIKSKDENLNNLQNKINNYENESKTNNEKIKEMEGKQKSNELQ 1785 Query: 820 EDELVNRLAVLMDHDRVVEK--------------QLLEIEHENKELQKKNQILLEENQNL 865 ++L N ++ + ++ ++ QL EI++E+K ++ +E ++ Sbjct: 1786 INDLQNNVSQTENENKQLKSELEKLQTEIKSKSDQLNEIQNESKSQSEQIVTFQDEVKSK 1845 Query: 866 QISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEI 925 L ++ L K N + + Q QL D E L + ++ L+ K++ Sbjct: 1846 DEKLQTQEEQIKELENKLNELENSLRNKGDLQVQLNDREKELNNLKKVNENLV----KQV 1901 Query: 926 EDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMN 985 EDL++ +K+ ++K +N E +T L + K E L N +E N+ Sbjct: 1902 EDLQV-----------NKEQSDKKLSENDEELTNLRRNNADLKKQNEKLREN-KEKNESE 1949 Query: 986 LELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKI--NNAQVSYMSMV 1043 + + + + D ++ + N+++KQ++ +I L Q++ N + + + Sbjct: 1950 IISLQNRLSELTNSHNDELFTVKRKLEENNSIVKQQNAKIEMLKQQLIDQNKTIEDLQKI 2009 Query: 1044 SDYESKLAQFTTKLENMEEEMQRVSKQL-LDSKQHNEELQILVREQDDQIKELKETKLTF 1102 + L + L+ +++V++ L +K+ NE+L + + +++KE +++ Sbjct: 2010 INESENLQFLVSTLKTENNTLKKVTQDNDLQNKKTNEDLLSQINDLQNKLKETEKSSQIQ 2069 Query: 1103 EMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXL-KVQEEEEFIQERSVLQEQS 1161 + I S + + D+++ +D L + Q+++ ++++ + + Sbjct: 2070 KSKYESQLNEIQSKLNQSIKDNSDLMDKHENELKNLDEKLQESQKQKNDLEKKFEMNSKL 2129 Query: 1162 AKLNTEL-QECYTKIIQLETLNTELTGHDVVNQEQINQL-KSKLEQ---LNTENDNLLST 1216 N +L QE + K LE L T + + +EQI+ L K K E LNT +N Sbjct: 2130 LNENNKLRQEKFDK--TLEEL-TNVKSENGKLKEQIDDLEKEKNEMTILLNTTQNNQNED 2186 Query: 1217 VAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQ 1276 + L+ +++ +D+ L D+ + + +L+ L+ S++ Sbjct: 2187 LQNLQKKLNATIDE------------LKMTTNDYNSLKEKFE-KLNGKSDNDNSLISSLK 2233 Query: 1277 SSTQEETNKI-VTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFX 1335 + N + T E+ SL KL + E+ + LQ+ ++ ++ + E E+ ++ Sbjct: 2234 RENDKMKNDLQKTQEENKSLVLKLNENEKTISKLQKTNDEISRKLTFV--ETENGELKLT 2291 Query: 1336 XXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRV 1395 + + S Q Q + + N N+ KS ++ Sbjct: 2292 VNEMDEKVTTNETNSNEKERLISNLQKQNKQLENENKTLQSEIKSLQTDEFVKDQMKKQL 2351 Query: 1396 NDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEK 1455 ND E KV +L + +E+ K + T+ + + E + Q+L ++EDLT K Sbjct: 2352 NDYEQKVSKLEDEKRQLQNEM-TKYKDDNSTMKKVLTKQEKIIQKL---NTKVEDLTETK 2407 Query: 1456 ES-------ELAILRLKMHENANHYETMQKE--SEIERVKLIEELNVKITESVSLNK-QV 1505 ++ EL+ L + + + +++E + +R+K +E+ K+TE ++ K ++ Sbjct: 2408 QTMKQTQSEELSSLEEENEQKKEELKHLKEEFLEKEKRLKGLEKSIQKVTEKITSQKEEI 2467 Query: 1506 AELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTK 1565 L K + +E+++++ E E+ L ++ +++ S+ +++S + ++ Sbjct: 2468 ENLRKQKLIDDNTISELKSSISENEKELENLRKSDSDKSDIIEQLKSE-SENLSMSLKSR 2526 Query: 1566 QGRDEQLDNTMNK--ELLDAVPRAELDL 1591 + +L NK +L D + E DL Sbjct: 2527 SNYENELTKLQNKIQKLNDQISDKEDDL 2554 Score = 139 bits (336), Expect = 7e-31 Identities = 272/1292 (21%), Positives = 545/1292 (42%), Gaps = 128/1292 (9%) Query: 313 KGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISR 372 K +L I N + K+IE L HLN +++Q N+E E+ + S+ S + + + Sbjct: 227 KSNLNIQNNADNLKEIEDLRHLNQELQQKNREQESLI------SQRTSELADARNEIFKL 280 Query: 373 KSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKD 432 +NT S +KS + QDT+ K +A+L + +K L K KD Sbjct: 281 SQNQNTESPIKS---------ILQDTESK-----VAELNTKLMEADKKLKSK-----TKD 321 Query: 433 TXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIH-VGTNTEDV-NEIAKVQEQLKQELN 490 + L+ Q +Q+ + + + +D+ ++ A K + N Sbjct: 322 FETLEQKY-----NVLLEQFHTINQEKKAAADQVEALKSQIKDLQSKSANSSSDFKAKQN 376 Query: 491 DEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNF-SK 549 + K +K + E K+ E I + DE+ +N N K ++N Q+ ++N + Sbjct: 377 EIDK---LKQINEAQKNFIEDIQRKYDELSQSNLNSPKERTN------PFQQELENLRRR 427 Query: 550 VSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIE--MEN 607 + D +KE LT++ L+ ++ L K LQ S + +E + + E ++N Sbjct: 428 LQDQDKENKALTDQNMALNNQINFL---KSQLQNSRQPLPSTQYMEEENSSNLDESDIQN 484 Query: 608 LAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQ 667 + ET + IS E++ +L + + L+ + D A + + S +KS + EE Sbjct: 485 MLETN-QVISDYENKIKELNETILSLRNAAPKTPDTSAKMKREN-----SLLKSEN-EEL 537 Query: 668 IDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENM-DLTDKLEK 726 + ++ KKE + +++ QL KD ++ +N ++ ++ + D +++K Sbjct: 538 VSRVNQIKKENTQLKSDIQDLNNQLRNKKKDFAGSVQNQLNIIKLFLNKLFADFNYEIQK 597 Query: 727 MSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESI- 785 + +KIS+ I + Q + + + K+ ER I +++ E K K +I L+ ++ Sbjct: 598 -TKQKISDEFLTILRKLQQQKENETN-KTKLLERQ--INDLKQENMKLKDKINDLQNNLQ 653 Query: 786 -AVMEDRRYS--LERKADQLGSYLQEKQKAYSEYTIQEDELVNRL-AVLMDHDRVVEKQL 841 + E+ +S + D L ++E+ + + + L N++ +D D+ + Sbjct: 654 KILQENENHSKQISTHIDGLSQSIKERDDQILKDKEKIENLQNKIKGKEIDFDQEKSNLI 713 Query: 842 LEIEHENKEL-----QKKNQILLEENQNLQISLSDMQQHYNALVEKANRTD-LAESESTK 895 + E + K+L K ++L E ++ L +Q L EK D + K Sbjct: 714 KQNEQKMKDLTDEMENLKRKLLDNELDVVKDQLQKEKQKSQDLEEKIEEKDSTIQILKEK 773 Query: 896 YQTQLRDLESNLKRITHEHQTLIVQKKKEIEDL-EIEFNTQIESAIRDKKVLNEKYEKNI 954 L + + + ++ ++ Q I +K+I +L E+ N S + +L E N Sbjct: 774 INENLEESKKSYDKLMNDKQEEIALLQKQINELQELIKNNGESSKTKISSLLQENTNLNT 833 Query: 955 EYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQT---QSPDYTEQYINEI 1011 + + QL + L++ + I +L + +L + ++L +K +Q QT S E +I Sbjct: 834 K-IQQLNSLLKQKDDKINDLQNEINDLTQNKIDL-EKQIQNLQTIIFDSKSQIESLNEKI 891 Query: 1012 NKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLA----QFTTKLENME---EEM 1064 + L LLK E I +LN KI Q+ + D+ KL + K E+ + +++ Sbjct: 892 SGLQQLLKSSQETIDSLNDKIKQTQIE-LQESKDFAEKLQNDINEEKKKTEDYQLKLDDI 950 Query: 1065 QRVSKQ--LLDSKQH-----NEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISST 1117 R++K+ LL + N E + + D+I++L + I + +IS Sbjct: 951 DRLTKERNLLKETEKSLTLTNAENMQTIDKLKDEIEQLNDKISQLNTTIDQLND-VISKK 1009 Query: 1118 IEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQ 1177 E + D + + Q E ++ ++L+E+ K++ E + KI++ Sbjct: 1010 DEEIKQDLQKFELSEKVHQAAINDYQKQLEHH-EEQITLLEEEIEKISKENSDLKAKILE 1068 Query: 1178 LETLNTELTGHDVVNQEQINQLKSKLEQLNTE---NDNLLSTVAELRSSISSAVDQRGFE 1234 E +L D V+ +Q ++ K+K+EQL E ++ L ++E ++ +++ + Sbjct: 1069 NE---AKLDDFDDVS-KQNSEYKAKIEQLEEELADYESNLQKLSEENGNLEIQIEEIKLK 1124 Query: 1235 -IAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVT 1293 + L + D + EL+ +L A + +Q++ I+ ++ Sbjct: 1125 TVPNTDFNELRTKNTDLEAQIRELK-RLLANDDGNKQVIAQKDKEILSLNQTIIDLQHNN 1183 Query: 1294 SLQN-KLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDL 1352 L N K++D E N E+ N E L IED V+ L Sbjct: 1184 QLLNDKIKDIEMTKTNYPER---SFNNDE-LHQTIEDNNVSM-----------FDMQNKL 1228 Query: 1353 RTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELK 1412 N KQ E+ I N+ E L+ + + E ++ EL + +K Sbjct: 1229 NLANLKLKQ-SEKEIQNLKNELLSLQSENEEMNSTINMLKQSLTSKENEINELNDSVTVK 1287 Query: 1413 DSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANH 1472 +S+I + + + + ++ E Q L K D+ EK + + + Sbjct: 1288 NSQIEEILKKNQVKFDKTGNK-EQQLQVLNSSLKHSNDIIQEKGKTIDSQNKLIKNLEDT 1346 Query: 1473 YETMQKES-EIER--VKLIEELNVKITESVSLNKQVAELNKALEEE---VAKTNEMQTAL 1526 + +QK++ +++ L +L E +SL + K LE+E + K E + + Sbjct: 1347 KQKLQKQNFDLQNNVSNLTNDLEKTKRELLSLQNSKNDNIKQLEQEKELILKQKENENKI 1406 Query: 1527 ENQEIEIVTLNDEITNLQNMVRASSSKIQKHV 1558 ++I+ +TL +I+NLQN + ++IQ ++ Sbjct: 1407 SEEKIKNLTL--QISNLQNTISQKDNEIQNNL 1436 Score = 105 bits (253), Expect = 8e-21 Identities = 151/788 (19%), Positives = 334/788 (42%), Gaps = 77/788 (9%) Query: 806 LQEKQKAYSEY-TIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQIL--LEEN 862 ++ ++ A Y +Q++ELV + L+D ++ +L N +Q L +E+ Sbjct: 186 IEMRRTASERYGRLQQEELVQENSQLLDRIEALQNELNNSNKSNLNIQNNADNLKEIEDL 245 Query: 863 QNLQISLSDMQQHYNALVEKANRTDLAESESTKYQ-TQLRDLESNLKRITHEHQTLIVQK 921 ++L L + +L+ + ++LA++ + ++ +Q ++ ES +K I + ++ K Sbjct: 246 RHLNQELQQKNREQESLISQ-RTSELADARNEIFKLSQNQNTESPIKSILQDTES----K 300 Query: 922 KKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEEL 981 E+ +E + +++S +D + L +KY +E + + + + +E L +++L Sbjct: 301 VAELNTKLMEADKKLKSKTKDFETLEQKYNVLLEQFHTINQEKKAAADQVEALKSQIKDL 360 Query: 982 NKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMS 1041 K S D+ + NEI+K LKQ +E A I + Q Y Sbjct: 361 Q-----------SKSANSSSDFKAKQ-NEIDK----LKQINE---AQKNFIEDIQRKYDE 401 Query: 1042 MVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLT 1101 + +S L + ++E++ + ++L D + N+ L ++QI LK Sbjct: 402 L---SQSNLNSPKERTNPFQQELENLRRRLQDQDKENKALTDQNMALNNQINFLKSQLQN 458 Query: 1102 FEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQS 1161 +P T+ M ++++N+D + + + E I+E L E Sbjct: 459 SRQPLPSTQYM--------EEENSSNLDESDIQNMLETNQV-ISDYENKIKE---LNETI 506 Query: 1162 AKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELR 1221 L + +++ N+ L + ++NQ+K + QL ++ +L + + + Sbjct: 507 LSLRNAAPKTPDTSAKMKRENSLLKSENEELVSRVNQIKKENTQLKSDIQDLNNQLRNKK 566 Query: 1222 SSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQE 1281 + +V Q I +L+ L ADF +E++ ++ +L +Q + Sbjct: 567 KDFAGSV-QNQLNIIKLFLNKLF---ADF---NYEIQKTKQKISDEFLTILRKLQQQKEN 619 Query: 1282 ETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXX 1341 ETNK +E+ ++ D ++ L++K D+ N ++ + E E+ Sbjct: 620 ETNKTKLLER------QINDLKQENMKLKDKINDLQNNLQKILQENENHSKQISTHIDGL 673 Query: 1342 XXXXXXXXXDLRTENQSYKQMQEQ---SILNINEENAQLKKSSXXXXXXXXXXXXRVN-- 1396 + + + + +Q + ++ ++E + L K + + Sbjct: 674 SQSIKERDDQILKDKEKIENLQNKIKGKEIDFDQEKSNLIKQNEQKMKDLTDEMENLKRK 733 Query: 1397 --DAEAKVLELTHQLE-LKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTY 1453 D E V++ Q E K ++ +K E T+ E + + L E +K + L Sbjct: 734 LLDNELDVVKDQLQKEKQKSQDLEEKIEEKDSTIQILK---EKINENLEESKKSYDKLMN 790 Query: 1454 EKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALE 1513 +K+ E+A+L+ +++E E ++ E + K+ L E+ +LN ++ +LN L+ Sbjct: 791 DKQEEIALLQKQINE---LQELIKNNGESSKTKISSLLQ----ENTNLNTKIQQLNSLLK 843 Query: 1514 EEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQ---KHVSFASDTKQGRDE 1570 ++ K N++Q + + + L +I NLQ ++ S S+I+ + +S + E Sbjct: 844 QKDDKINDLQNEINDLTQNKIDLEKQIQNLQTIIFDSKSQIESLNEKISGLQQLLKSSQE 903 Query: 1571 QLDNTMNK 1578 +D+ +K Sbjct: 904 TIDSLNDK 911 Score = 64.5 bits (150), Expect = 2e-08 Identities = 122/613 (19%), Positives = 251/613 (40%), Gaps = 72/613 (11%) Query: 1008 INEINKLNALLKQKDEEIIALN-QKINNAQVSYMSMVSDYESKLAQFTT-KLENMEEEMQ 1065 I++I++L+ L + K+ ++ + I+ Q S + ++ L Q T ++N+ EM+ Sbjct: 134 ISDISELHKLTECKNLTLLDIEGTPISRDQSSELYLIYI----LPQLTVINMKNITIEMR 189 Query: 1066 RVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSD-- 1123 R + + Q E LV+E + ++ L E+N + I + + + + Sbjct: 190 RTASERYGRLQQEE----LVQENSQLLDRIEA--LQNELNNSNKSNLNIQNNADNLKEIE 243 Query: 1124 DANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTE------LQECYTKIIQ 1177 D +++ L Q E R+ + + S NTE LQ+ +K+ + Sbjct: 244 DLRHLNQELQQKNREQESLISQRTSELADARNEIFKLSQNQNTESPIKSILQDTESKVAE 303 Query: 1178 LETLNTELTGHDVVNQEQINQLKSK----LEQLNTENDNLLSTVAELRSSISSAVDQRGF 1233 L T E + L+ K LEQ +T N + ++ + S D + Sbjct: 304 LNTKLMEADKKLKSKTKDFETLEQKYNVLLEQFHTINQEKKAAADQVEALKSQIKDLQSK 363 Query: 1234 EIAELWKQHLAQREADFQKTEHELRVQ-LSAFESKYEQLLDSVQSSTQEETNKIVTMEQV 1292 Q E D K +E + + + KY++L S +S +E TN +++ Sbjct: 364 SANSSSDFKAKQNEIDKLKQINEAQKNFIEDIQRKYDELSQSNLNSPKERTNPF--QQEL 421 Query: 1293 TSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDL 1352 +L+ +LQD+++ + L ++ + NQI L+S++++ + + Sbjct: 422 ENLRRRLQDQDKENKALTDQNMALNNQINFLKSQLQNSRQPLPSTQY------------M 469 Query: 1353 RTENQSYKQMQEQSILNINEENAQLK------KSSXXXXXXXXXXXXRVNDAEAKVLELT 1406 EN S + E I N+ E N + K + D AK+ Sbjct: 470 EEENSS--NLDESDIQNMLETNQVISDYENKIKELNETILSLRNAAPKTPDTSAKMKREN 527 Query: 1407 HQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKM 1466 L+ ++ E+ + ++ TQ + +++ QL +K D +++L I++L + Sbjct: 528 SLLKSENEELVSRVNQIKKENTQLKSDIQDLNNQLRNKKK---DFAGSVQNQLNIIKLFL 584 Query: 1467 HENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTAL 1526 ++ + EI++ K KI++ + +L + E E KT ++ + Sbjct: 585 NKLFADFNY-----EIQKTKQ------KISDEFLTI--LRKLQQQKENETNKTKLLERQI 631 Query: 1527 ENQEIEIVTLNDEITNLQNMVRA-------SSSKIQKHVSFASDTKQGRDEQL--DNTMN 1577 + + E + L D+I +LQN ++ S +I H+ S + + RD+Q+ D Sbjct: 632 NDLKQENMKLKDKINDLQNNLQKILQENENHSKQISTHIDGLSQSIKERDDQILKDKEKI 691 Query: 1578 KELLDAVPRAELD 1590 + L + + E+D Sbjct: 692 ENLQNKIKGKEID 704 >UniRef50_Q24HK7 Cluster: Viral A-type inclusion protein repeat containing protein; n=1; Tetrahymena thermophila SB210|Rep: Viral A-type inclusion protein repeat containing protein - Tetrahymena thermophila SB210 Length = 1608 Score = 208 bits (508), Expect = 1e-51 Identities = 289/1402 (20%), Positives = 602/1402 (42%), Gaps = 135/1402 (9%) Query: 212 EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271 E K Q+ K N + E E+Q +E K+++ + KL+++ + E+ Sbjct: 200 ETLKVQLEK--SNSLYAEVRKIIEEQEAYIVVEKKELQ-EKQQSQEKLIQSLQQEVKRNE 256 Query: 272 SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTE-LTKKIEL 330 L Q+ + Q+I+ S + ++ ++ + N+ + L K E Sbjct: 257 ENLIQKTNELLKTVEDNNEWQERF--QNIKKSVSDSDKLLKEQENIVKNLEQQLLNKSEQ 314 Query: 331 LEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKM-KSPWSQL 389 + L Q Q ++ L+ A E++ + +KK L S + T ++ K QL Sbjct: 315 INQLTQQNDQLSEALKKLKAQASNENQNIDHLNKKIEELNSLMQQKETEKEVAKEEKQQL 374 Query: 390 SSETLNQDTDKKINKNEIAKLEMVIQSLNKDL-VDK---EYVISEKDTXXXXXXXXXXGK 445 +T Q NK +IA++++ I++LN +L V K E + K K Sbjct: 375 QLKTEEQ------NK-QIAEMQVQIENLNSELKVSKQNYEESMQNKQNSQEIEDKLESEK 427 Query: 446 DTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEI-KDVNVKDLIEK 504 + L QL+ ++ + + G + E++ + + +QLK++L +I K+ ++ D I + Sbjct: 428 NALKEQLENKYNE-ICGQKDAQISQLQEEIQKYSLEIQQLKEQLQQQINKEASLNDQISQ 486 Query: 505 LKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFS-KVSDSNKEIVRLTEE 563 L+ E+I L ++D ++ + + ++ +Q + + ++++ K+++ + Sbjct: 487 LQKESEEIANLKQQLDQVQNKQNEILAQKQQEVTDLQNQLQEMTAQINEGTKKLLDQENK 546 Query: 564 LHHLSQKVAEL---EEEKGNLQLHLVDYDSGRMIESDVYKKMIEME----NLAETRLKAI 616 H LSQ++ EL +++ LQ +V + +I+ N + + I Sbjct: 547 NHSLSQQIQELVNVQQKNIELQNQIVQLQENEQKQGQEKHSLIQKNEHQVNEINQQKEQI 606 Query: 617 SLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVH--LEEQIDALSAS 674 + L++++ +L +++ L+ +E ED + + Q + + + ++ S+ LEE+I+ L Sbjct: 607 TKLQAEQRELEEKVQKLKDTIEENEDMINKLKQKEQN-ITNDSSSLKQKLEEEIEELKRH 665 Query: 675 KKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISE 734 E V E +++ ++ +E K+DI ++ +E ++D++ K++ E+ Sbjct: 666 AHE---VKEQFNVERGEI------IEKHKQDIQKLQESLSKEGQGISDEIAKLNEERTK- 715 Query: 735 LLAKINHEEQSKIQT-QFGIDAKIQERDLYIENIESELSKY---KSRICRLEE----SIA 786 L+ N E + I+ Q I AK +E ++N+E ++ ++ K +LEE S Sbjct: 716 -LSDENFELKQNIKDHQKDIQAKEEEIKKIMKNLEEQIQQFNNLKDSYNKLEEESNKSKK 774 Query: 787 VMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEH 846 E R L K + L+ K + Q+DE + +L +QL + Sbjct: 775 DFEKRMEKLSSKKKEALEKLENNIKELNIQVQQKDEAIQKLETEKTETEKKYQQLKKDSS 834 Query: 847 ENKELQKK-----NQILLEE---NQNLQISLSDMQQHYNALVEKANRTDLAESESTK--Y 896 +Q++ NQI E +Q LQ ++++Q++ A ++K N + E ++ K + Sbjct: 835 TQSSIQEELNAQINQIKQEYELISQKLQSENNELKQNHEAQIKKLNADQIEEVQNLKDQF 894 Query: 897 QTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKY------ 950 Q Q L+ NL + + Q L Q K + E+ ++ + + + ++L +Y Sbjct: 895 QQQTEQLKQNLSQ---QEQELTQQIKIKEEEYNVKLEDEKYITVDNNRILVREYIQQLQC 951 Query: 951 --EKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYI 1008 E+ + + QLE QLQE K+ I NL + L K +E ++ + T+ + E Sbjct: 952 ESEQKRDQIKQLEQQLQEKKDQISNLETQIPLL-KQKIEQLECELNSHLTEKQNQQESQ- 1009 Query: 1009 NEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVS 1068 N+ L QKDE I L +I+ + ++ E L + K + ++S Sbjct: 1010 ------NSSLSQKDEAIKLLQTQISQQEEQLKELIQHKEDNLQSHSEKDSQINSLTSQIS 1063 Query: 1069 KQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNV 1128 Q+L ++ ++ L RE+D+ KE KE++ N E ++ + +SD + Sbjct: 1064 DQVLKLEELQKQKDELQREKDELQKE-KESQQQESQNQLIQEITLLK---QQLSDSQKQI 1119 Query: 1129 DXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAK-LNTELQECYTKIIQLETLNTELTG 1187 + K + +QE +E+ AK L +L + + + + + Sbjct: 1120 EENEKQIAQISQEHKTVVDG--LQESYNRKEKEAKQLEDQLIRIQQQHQEEQAELQKKSQ 1177 Query: 1188 HDVVNQEQINQLKSK-LEQLNTENDNLLSTVAELRSSISSAVDQRGFE-----IAELWKQ 1241 D N ++N+ K +E L N L++ + + S++S+ +D + I E K Sbjct: 1178 LDSSNMVKLNEKNQKNIEALKRGNRELINMIIDSYSALSNQLDNANIQSQVNAITECIKN 1237 Query: 1242 HLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIV-----TMEQVTSLQ 1296 +FQK E R +S Y+ +++V++ ++ NK++ + + + L Sbjct: 1238 TSPDIMKEFQKFLLESRNLIS---EHYQNQINNVKNQEKQRYNKLLEQFNKSQDDIKQLN 1294 Query: 1297 NKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTEN 1356 +K++ E+ R +QE Y+D+I + + I+ ++ AF D RTE Sbjct: 1295 SKIKAAEKLERQVQE-YSDII---ALQKQTIQKKEAAFKDLQIEISSSDA----DKRTE- 1345 Query: 1357 QSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEI 1416 +QE+ L + ++N QL + + D E +L + + S++ Sbjct: 1346 --LANLQEKVQL-LKQKNEQLISENTAQKELNAKILHDIQDLEQSKAQLEEKAN-QGSDL 1401 Query: 1417 YQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETM 1476 E + + +++ +++KR E L + + EL +R ++ ++ Sbjct: 1402 IMLIQEKDSQIQALEESLSSLQTIHEDFQKRNEQLAKKYDFELKKIRTELAQSK------ 1455 Query: 1477 QKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTL 1536 E++ L++EL Q+A+L A E+ K N +Q E E + Sbjct: 1456 ------EKIALVDELTA----------QIAQLESAFNEKNQKYNTLQEKYAESEKERALI 1499 Query: 1537 NDEITNLQNMVRASSSKIQKHV 1558 +E L N +++ + K + + Sbjct: 1500 KNETNQLLNKLKSDAVKSEYQI 1521 Score = 186 bits (452), Expect = 6e-45 Identities = 250/1216 (20%), Positives = 538/1216 (44%), Gaps = 97/1216 (7%) Query: 396 QDTDKKINKNEIAKLEMVIQSLNKDLVDKE-YVISEKDTXXXXXXXXXXGKDTLIAQLQL 454 Q D + K ++ K + + K + ++E Y++ EK ++ LI LQ Sbjct: 195 QKEDYETLKVQLEKSNSLYAEVRKIIEEQEAYIVVEKKELQEKQQS----QEKLIQSLQQ 250 Query: 455 EHQQHMEG--PSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVN-----VKDLIEKLKS 507 E +++ E + ED NE + + +K+ ++D K + VK+L ++L + Sbjct: 251 EVKRNEENLIQKTNELLKTVEDNNEWQERFQNIKKSVSDSDKLLKEQENIVKNLEQQLLN 310 Query: 508 AEEQITQL---NDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKV---SDSNKEIVRLT 561 EQI QL ND++ A K + SN + + K I+ + + ++ KE+ + Sbjct: 311 KSEQINQLTQQNDQLSEALKKLKAQASNENQNIDHLNKKIEELNSLMQQKETEKEVAK-- 368 Query: 562 EELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIE-MENLAETRLKAISLLE 620 EE L K E ++ +Q+ + + +S + Y++ ++ +N E K LE Sbjct: 369 EEKQQLQLKTEEQNKQIAEMQVQIENLNSELKVSKQNYEESMQNKQNSQEIEDK----LE 424 Query: 621 SQKFDLVQELHILQQKYDEV-EDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELA 679 S+K L ++L + KY+E+ K A ISQLQ + ++ L+EQ+ + L Sbjct: 425 SEKNALKEQL---ENKYNEICGQKDAQISQLQEEIQKYSLEIQQLKEQLQQQINKEASLN 481 Query: 680 LVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKI 739 I L+ + E++ + L+ + L QE DL ++L++M+A+ I+E K+ Sbjct: 482 DQISQLQKESEEIANLKQQLDQVQNKQNEILAQKQQEVTDLQNQLQEMTAQ-INEGTKKL 540 Query: 740 NHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKA 799 +E + +IQE + N++ + + +++I +L+E+ ++SL +K Sbjct: 541 LDQENKN----HSLSQQIQE----LVNVQQKNIELQNQIVQLQENEQKQGQEKHSLIQKN 592 Query: 800 DQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILL 859 + + + ++++ ++ ++ EL ++ L D E + +++ + + + + L Sbjct: 593 EHQVNEINQQKEQITKLQAEQRELEEKVQKLKDTIEENEDMINKLKQKEQNITNDSSSL- 651 Query: 860 EENQNLQISLSDMQQHYNALVEKAN--RTDLAESESTKYQTQLRDLESNLKRITHEHQTL 917 Q L+ + ++++H + + E+ N R ++ E K++ ++ L+ +L + Sbjct: 652 --KQKLEEEIEELKRHAHEVKEQFNVERGEIIE----KHKQDIQKLQESLSKEGQGISDE 705 Query: 918 IVQKKKEIEDLEIEFNTQIESAIRD-KKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNM 976 I + +E L E N +++ I+D +K + K E+ + + LE Q+Q++ N ++ N Sbjct: 706 IAKLNEERTKLSDE-NFELKQNIKDHQKDIQAKEEEIKKIMKNLEEQIQQFNNLKDSYNK 764 Query: 977 NVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQ 1036 EE NK + +K ++K ++ + E+ N I +LN ++QKDE I L + + Sbjct: 765 LEEESNKSKKDF-EKRMEKLSSKKKEALEKLENNIKELNIQVQQKDEAIQKLETEKTETE 823 Query: 1037 VSYMSMVSDYESKLA---QFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIK 1093 Y + D ++ + + ++ +++E + +S++L + N EL+ + + QIK Sbjct: 824 KKYQQLKKDSSTQSSIQEELNAQINQIKQEYELISQKL---QSENNELK---QNHEAQIK 877 Query: 1094 ELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQE 1153 +L ++ N+ + +S + +K+++E+ + Sbjct: 878 KLNADQIEEVQNLKDQFQQQTEQLKQNLSQQEQEL-TQQIKIKEEEYNVKLEDEKYITVD 936 Query: 1154 --RSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTEND 1211 R +++E +L E ++ +I QLE E + QI LK K+EQL E + Sbjct: 937 NNRILVREYIQQLQCESEQKRDQIKQLEQQLQEKKDQISNLETQIPLLKQKIEQLECELN 996 Query: 1212 NLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQL 1271 + L+ + S +S++ Q+ E +L + ++Q+E ++ L + K Q Sbjct: 997 SHLTEKQNQQESQNSSLSQKD-EAIKLLQTQISQQEEQLKELIQHKEDNLQSHSEKDSQ- 1054 Query: 1272 LDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRN-----LQEKYADVINQIEILRSE 1326 + S T + +++++ +E++ +++LQ +++ L+ QE +I +I +L+ + Sbjct: 1055 ---INSLTSQISDQVLKLEELQKQKDELQREKDELQKEKESQQQESQNQLIQEITLLKQQ 1111 Query: 1327 IEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSY-------KQMQEQSIL---NINEENAQ 1376 + D + + +SY KQ+++Q I EE A+ Sbjct: 1112 LSDSQKQIEENEKQIAQISQEHKTVVDGLQESYNRKEKEAKQLEDQLIRIQQQHQEEQAE 1171 Query: 1377 LKKSSXXXXXXXXXXXXRVNDAEAKVL-----ELTHQLELKDSEIYQKTHEYTITLTQRN 1431 L+K S + N + L EL + + S + + I +Q N Sbjct: 1172 LQKKSQLDSSNMVKLNEK-NQKNIEALKRGNRELINMIIDSYSALSNQLDNANIQ-SQVN 1229 Query: 1432 DEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKL---- 1487 E ++ + K + E + ++ N + E + +E+ Sbjct: 1230 AITECIKNTSPDIMKEFQKFLLESRNLISEHYQNQINNVKNQEKQRYNKLLEQFNKSQDD 1289 Query: 1488 IEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLN----DEITNL 1543 I++LN KI + L +QV E + + + + + A ++ +IEI + + E+ NL Sbjct: 1290 IKQLNSKIKAAEKLERQVQEYSDIIALQKQTIQKKEAAFKDLQIEISSSDADKRTELANL 1349 Query: 1544 QNMVRASSSKIQKHVS 1559 Q V+ K ++ +S Sbjct: 1350 QEKVQLLKQKNEQLIS 1365 Score = 156 bits (379), Expect = 4e-36 Identities = 213/1102 (19%), Positives = 476/1102 (43%), Gaps = 65/1102 (5%) Query: 479 AKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQ-LNDEIDAANKNMIKVKSNHKLKL 537 ++ + +++ D+ K+ + D I++LK E+ +++ L + K I N LK Sbjct: 64 SQTNKNKQEDFKDQQKEKLLLDHIQQLKQIEKSLSEPLQNSTPEDQKKKITSMVNTILK- 122 Query: 538 KQMQKTIDNFSK--VSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQ-LHLVDYDSGRMI 594 + M K I+ + V ++ +V+L +E +L + + ++K L+ + VDYD ++ Sbjct: 123 ENMMKFIEKVKQQIVIKIHERVVKLIDE--NLGDDIPK--DQKDQLKTIFNVDYDEKDLM 178 Query: 595 ESDV---YKKMIEMENLAET--RLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQ 649 + + Y ++++ E LK + + V+++ Q+ Y VE K Q Sbjct: 179 QQNEEFNYDNILQLFVQKEDYETLKVQLEKSNSLYAEVRKIIEEQEAYIVVEKKELQEKQ 238 Query: 650 LQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNK 709 +++ ++ ++ + L EL +E+ + ++ + IK +D + ++ + Sbjct: 239 QSQEKLIQSLQQ-EVKRNEENLIQKTNELLKTVEDNN-EWQERFQNIKKSVSDSDKLLKE 296 Query: 710 LQNYIQE-NMDLTDKLEKMSA-----EKISELLAKINHEEQSKIQTQFGIDAKIQERDLY 763 +N ++ L +K E+++ +++SE L K+ + ++ Q ++ KI+E + Sbjct: 297 QENIVKNLEQQLLNKSEQINQLTQQNDQLSEALKKLKAQASNENQNIDHLNKKIEELNSL 356 Query: 764 IENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDEL 823 ++ E+E K +L+ + ++ + + L S L+ ++ Y E ++Q + Sbjct: 357 MQQKETEKEVAKEEKQQLQLKTEEQNKQIAEMQVQIENLNSELKVSKQNYEE-SMQNKQN 415 Query: 824 VNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQI--LLEENQNLQISLSDMQQHYNALVE 881 + ++ ++ K+ LE ++ QK QI L EE Q + + +++ + Sbjct: 416 SQEIEDKLESEKNALKEQLENKYNEICGQKDAQISQLQEEIQKYSLEIQQLKEQLQQQIN 475 Query: 882 KANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIR 941 K + S+ K ++ +L+ L ++ ++ ++ QK++E+ DL+ + Sbjct: 476 KEASLNDQISQLQKESEEIANLKQQLDQVQNKQNEILAQKQQEVTDLQNQLQEMTAQINE 535 Query: 942 DKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKH--VQKQQTQ 999 K L ++ KN Q++ + + NIE N V+ + +KH +QK + Q Sbjct: 536 GTKKLLDQENKNHSLSQQIQELVNVQQKNIELQNQIVQLQENEQKQGQEKHSLIQKNEHQ 595 Query: 1000 SPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKL-E 1058 + +Q +I KL A ++ +E++ L I + ++ + E + ++ L + Sbjct: 596 VNEINQQK-EQITKLQAEQRELEEKVQKLKDTIEENE-DMINKLKQKEQNITNDSSSLKQ 653 Query: 1059 NMEEEMQRVSKQLLDSK-QHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISST 1117 +EEE++ + + + K Q N E ++ + I++L+E+ EG IS Sbjct: 654 KLEEEIEELKRHAHEVKEQFNVERGEIIEKHKQDIQKLQESL--------SKEGQGISDE 705 Query: 1118 IEPMSDDANNV-DXXXXXXXXXXXXLK-VQEEEEFIQE-RSVLQEQSAKLNTELQECYTK 1174 I ++++ + D K +Q +EE I++ L+EQ + N L++ Y K Sbjct: 706 IAKLNEERTKLSDENFELKQNIKDHQKDIQAKEEEIKKIMKNLEEQIQQFN-NLKDSYNK 764 Query: 1175 IIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFE 1234 + E N + ++ ++ K LE+L L V + +I ++ Sbjct: 765 L--EEESNKSKKDFEKRMEKLSSKKKEALEKLENNIKELNIQVQQKDEAIQKLETEK--T 820 Query: 1235 IAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTS 1294 E Q L + + + EL Q++ + +YE + +QS E + Sbjct: 821 ETEKKYQQLKKDSSTQSSIQEELNAQINQIKQEYELISQKLQSENNE-----LKQNHEAQ 875 Query: 1295 LQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRT 1354 ++ D+ E ++NL++++ Q++ S+ E E +++ Sbjct: 876 IKKLNADQIEEVQNLKDQFQQQTEQLKQNLSQQEQE--------LTQQIKIKEEEYNVKL 927 Query: 1355 ENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDS 1414 E++ Y + IL + E QL+ S ++ + + ++ L Q+ L Sbjct: 928 EDEKYITVDNNRIL-VREYIQQLQCESEQKRDQIKQLEQQLQEKKDQISNLETQIPLLKQ 986 Query: 1415 EIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDL-TYEKESELAILRLKMHENANHY 1473 +I Q E LT++ ++ E+ L + ++ I+ L T + E + L H+ N Sbjct: 987 KIEQLECELNSHLTEKQNQQESQNSSLSQKDEAIKLLQTQISQQEEQLKELIQHKEDNLQ 1046 Query: 1474 ETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEI-E 1532 +K+S+I L +++ ++ + L KQ EL + +E + Q +NQ I E Sbjct: 1047 SHSEKDSQIN--SLTSQISDQVLKLEELQKQKDELQREKDELQKEKESQQQESQNQLIQE 1104 Query: 1533 IVTLNDEITNLQNMVRASSSKI 1554 I L ++++ Q + + +I Sbjct: 1105 ITLLKQQLSDSQKQIEENEKQI 1126 Score = 151 bits (365), Expect = 2e-34 Identities = 266/1248 (21%), Positives = 537/1248 (43%), Gaps = 151/1248 (12%) Query: 143 DVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXX 202 ++ HL+ I+E ++ + + + ++ + LQ K E+++ I A+ + Sbjct: 342 NIDHLNKKIEELNSLMQQKETEKEVAKEEKQQLQLKTEEQNKQI-AEMQVQIENLNSELK 400 Query: 203 XXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDI-ESKDVRISSLEEANKLLE 261 KQ ++++ + + K++ + +I KD +IS L+E E Sbjct: 401 VSKQNYEESMQNKQNSQEIEDKLESEKNALKEQLENKYNEICGQKDAQISQLQE-----E 455 Query: 262 AARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSC--EEKTEIEEKGSLEIA 319 ++ SLE +L ++L+Q L K+S E + ++ +++ K + +A Sbjct: 456 IQKY--SLEIQQLKEQLQQQINKEASLNDQISQLQKESEEIANLKQQLDQVQNKQNEILA 513 Query: 320 N-MTELTKKIELLEHLNCQIRQTNKEL---ENKLATMGTESKAVSSPSKKG----SPLIS 371 E+T L+ + QI + K+L ENK ++ + + + + +K + ++ Sbjct: 514 QKQQEVTDLQNQLQEMTAQINEGTKKLLDQENKNHSLSQQIQELVNVQQKNIELQNQIVQ 573 Query: 372 RKSGRNTASKMKSPWSQLSSETLNQDTDKK--INK--NEIAKLEMVIQSLNKDLVDKEYV 427 + + K Q + +N+ +K I K E +LE +Q L + + E + Sbjct: 574 LQENEQKQGQEKHSLIQKNEHQVNEINQQKEQITKLQAEQRELEEKVQKLKDTIEENEDM 633 Query: 428 ISE-KDTXXXXXXXXXXGKDTLIAQLQ--LEHQQHMEGPSLIHVGTNTED-VNEIAKVQE 483 I++ K K L +++ H ++ + G E +I K+QE Sbjct: 634 INKLKQKEQNITNDSSSLKQKLEEEIEELKRHAHEVKEQFNVERGEIIEKHKQDIQKLQE 693 Query: 484 QLKQE---LNDEIKDVNVK--DLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLK 538 L +E ++DEI +N + L ++ ++ I +I A + + K+ N + +++ Sbjct: 694 SLSKEGQGISDEIAKLNEERTKLSDENFELKQNIKDHQKDIQAKEEEIKKIMKNLEEQIQ 753 Query: 539 QMQKTIDNFSKVSD-SNKEIVRLTEELHHLSQKVAE-LEEEKGNL-QLHLVDYDSGRMIE 595 Q D+++K+ + SNK + + LS K E LE+ + N+ +L++ I+ Sbjct: 754 QFNNLKDSYNKLEEESNKSKKDFEKRMEKLSSKKKEALEKLENNIKELNIQVQQKDEAIQ 813 Query: 596 ------SDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKL----- 644 ++ KK +++ + T+ L +Q + QE ++ QK ++L Sbjct: 814 KLETEKTETEKKYQQLKKDSSTQSSIQEELNAQINQIKQEYELISQKLQSENNELKQNHE 873 Query: 645 ADISQLQSDQVCSEIKSV--HLEEQIDAL----SASKKELALVIE------NLKLDKEQL 692 A I +L +DQ+ E++++ ++Q + L S ++EL I+ N+KL+ E+ Sbjct: 874 AQIKKLNADQI-EEVQNLKDQFQQQTEQLKQNLSQQEQELTQQIKIKEEEYNVKLEDEK- 931 Query: 693 YGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEK---ISELLAKINHEEQSKIQT 749 Y T+ + + + +LQ ++ D +LE+ EK IS L +I +Q Q Sbjct: 932 YITVDNNRILVREYIQQLQCESEQKRDQIKQLEQQLQEKKDQISNLETQIPLLKQKIEQL 991 Query: 750 QFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSL-ERKADQLGSYLQE 808 + +++ + E+ E+ S LS+ I L+ I+ E++ L + K D L S+ E Sbjct: 992 ECELNSHLTEKQNQQESQNSSLSQKDEAIKLLQTQISQQEEQLKELIQHKEDNLQSH-SE 1050 Query: 809 KQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQIS 868 K + T Q + V +L L +KQ E++ E ELQK+ + Sbjct: 1051 KDSQINSLTSQISDQVLKLEEL-------QKQKDELQREKDELQKEKE------------ 1091 Query: 869 LSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDL 928 S Q+ N L+++ L + + + Q Q+ + E + +I+ EH+T++ ++ Sbjct: 1092 -SQQQESQNQLIQEIT---LLKQQLSDSQKQIEENEKQIAQISQEHKTVVDGLQESYNRK 1147 Query: 929 EIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLEL 988 E E + IR ++ E+ + ++ +QL++ K N +N N+E L + N EL Sbjct: 1148 EKEAKQLEDQLIRIQQQHQEE-QAELQKKSQLDSS-NMVKLNEKN-QKNIEALKRGNREL 1204 Query: 989 IDKHVQKQQTQSPDYTEQYI-NEINKLNALLKQKDEEIIALNQKI-----NNAQVSYMSM 1042 I+ + S I +++N + +K +I+ QK N Y + Sbjct: 1205 INMIIDSYSALSNQLDNANIQSQVNAITECIKNTSPDIMKEFQKFLLESRNLISEHYQNQ 1264 Query: 1043 VSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTF 1102 +++ +++ Q KL + Q KQL + E+L+ V+E D I K+T Sbjct: 1265 INNVKNQEKQRYNKLLEQFNKSQDDIKQLNSKIKAAEKLERQVQEYSDIIALQKQT---- 1320 Query: 1103 EMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSA 1162 I K E IE S DA+ +QE+ + +++++ EQ Sbjct: 1321 ---IQKKEAAFKDLQIEISSSDADK----------RTELANLQEKVQLLKQKN---EQLI 1364 Query: 1163 KLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRS 1222 NT +E KI+ HD+ + + Q K++LE+ + +L+ + E S Sbjct: 1365 SENTAQKELNAKIL-----------HDI---QDLEQSKAQLEEKANQGSDLIMLIQEKDS 1410 Query: 1223 SISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEE 1282 I + + ++ L H DFQK +L KY+ L +++ + Sbjct: 1411 QIQALEES----LSSLQTIH-----EDFQKRNEQLA-------KKYDFELKKIRTELAQS 1454 Query: 1283 TNKIVTMEQVTS----LQNKLQDKEEHLRNLQEKYADVINQIEILRSE 1326 KI ++++T+ L++ +K + LQEKYA+ + ++++E Sbjct: 1455 KEKIALVDELTAQIAQLESAFNEKNQKYNTLQEKYAESEKERALIKNE 1502 Score = 102 bits (244), Expect = 9e-20 Identities = 200/1091 (18%), Positives = 465/1091 (42%), Gaps = 80/1091 (7%) Query: 54 FERAQKCLENAALVSKRIKEHRKATAELLGRPFVPGISESLANTLKQKEILMEKIKQYKE 113 +E + + +N+ + +++ + A E L + + A + +E + + + ++ Sbjct: 406 YEESMQNKQNSQEIEDKLESEKNALKEQLENKYNEICGQKDAQISQLQEEIQKYSLEIQQ 465 Query: 114 LSKRSSTTIVRXXXXXXXXXXXXXXXQ-LGDVTHLSNTIKEKDNA-LSVLQVKMKIMETT 171 L ++ I + + + ++ + ++ K N L+ Q ++ ++ Sbjct: 466 LKEQLQQQINKEASLNDQISQLQKESEEIANLKQQLDQVQNKQNEILAQKQQEVTDLQNQ 525 Query: 172 ILDLQEKINE-KDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEA 230 + ++ +INE ++++ +NK + + + Q+ ++QEN E Sbjct: 526 LQEMTAQINEGTKKLLDQENKNHSLSQQIQELVNVQQKNI--ELQNQIVQLQEN----EQ 579 Query: 231 EWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXX 290 + EK L++ E + I+ +E L+A + E+ + KL +E+ Sbjct: 580 KQGQEKHSLIQKNEHQVNEINQQKEQITKLQAEQRELEEKVQKLKDTIEENEDMINKLKQ 639 Query: 291 XXXXLAKQS--IEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENK 348 + S ++ EE+ E ++ + E+ + + E++E + +Q ++L+ Sbjct: 640 KEQNITNDSSSLKQKLEEEIEELKRHAHEVKEQFNVERG-EIIE----KHKQDIQKLQES 694 Query: 349 LATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKN--- 405 L+ E + +S K + ++ S N K Q + ++ KKI KN Sbjct: 695 LSK---EGQGISDEIAKLNEERTKLSDENFELKQNIKDHQKDIQAKEEEI-KKIMKNLEE 750 Query: 406 EIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTL------IAQLQLEHQQH 459 +I + + S NK +++E S+KD K+ L I +L ++ QQ Sbjct: 751 QIQQFNNLKDSYNK--LEEESNKSKKDFEKRMEKLSSKKKEALEKLENNIKELNIQVQQK 808 Query: 460 MEGPSLIHVG-TNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDE 518 E + T TE + K + + +E+ + + + ++ + +++ N+E Sbjct: 809 DEAIQKLETEKTETEKKYQQLKKDSSTQSSIQEEL-NAQINQIKQEYELISQKLQSENNE 867 Query: 519 IDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEK 578 + ++ IK K N +++++Q D F + ++ K+ L+++ L+Q++ +++EE+ Sbjct: 868 LKQNHEAQIK-KLNAD-QIEEVQNLKDQFQQQTEQLKQ--NLSQQEQELTQQI-KIKEEE 922 Query: 579 GNLQLHLVDY---DSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELH---- 631 N++L Y D+ R++ + +++ ++K + +K D + L Sbjct: 923 YNVKLEDEKYITVDNNRILVREYIQQLQCESEQKRDQIKQLEQQLQEKKDQISNLETQIP 982 Query: 632 ILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQ 691 +L+QK +++E +L S L Q E ++ L ++ +A+ + +++ E LK + Sbjct: 983 LLKQKIEQLECELN--SHLTEKQNQQESQNSSLSQKDEAIKLLQTQISQQEEQLKELIQH 1040 Query: 692 LYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAE--KISELLAKINHEEQSKIQT 749 ++ ++K+ +N L + I + + ++L+K E + + L K +Q + Q Sbjct: 1041 KEDNLQS-HSEKDSQINSLTSQISDQVLKLEELQKQKDELQREKDELQKEKESQQQESQN 1099 Query: 750 QFGIDAKIQERDLYIENIESELSKYKSRICRL-EESIAVMEDRRYSLERKADQLGSYLQE 808 Q + + ++ L + + ++ + + +I ++ +E V++ + S RK + + Sbjct: 1100 QLIQEITLLKQQL--SDSQKQIEENEKQIAQISQEHKTVVDGLQESYNRKEKEAKQLEDQ 1157 Query: 809 KQKAYSEYTIQEDELVNRLAVLMDHDRVV---EKQLLEIEHENKELQKKNQILLEENQNL 865 + ++ ++ EL + +D +V EK IE + ++ ++++ L Sbjct: 1158 LIRIQQQHQEEQAELQKKSQ--LDSSNMVKLNEKNQKNIEALKRGNRELINMIIDSYSAL 1215 Query: 866 --QISLSDMQQHYNALVEKANRT--DLAESESTKYQTQLRDLESNLKRITHEHQTLIVQK 921 Q+ +++Q NA+ E T D+ + E K+ + R+L S + ++ + Q+ Sbjct: 1216 SNQLDNANIQSQVNAITECIKNTSPDIMK-EFQKFLLESRNLIS--EHYQNQINNVKNQE 1272 Query: 922 KKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEEL 981 K+ L +FN + D K LN K I+ +LE Q+QEY + I + + + Sbjct: 1273 KQRYNKLLEQFNKSQD----DIKQLNSK----IKAAEKLERQVQEYSDIIA---LQKQTI 1321 Query: 982 NKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMS 1041 K D ++ + + TE + + + LLKQK+E++I+ N + Sbjct: 1322 QKKEAAFKDLQIEISSSDADKRTE--LANLQEKVQLLKQKNEQLISENTAQKELNAKILH 1379 Query: 1042 MVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQIL--VREQDDQIKELKETK 1099 + D E AQ K + + + ++ + E L L + E + E K Sbjct: 1380 DIQDLEQSKAQLEEKANQGSDLIMLIQEKDSQIQALEESLSSLQTIHEDFQKRNEQLAKK 1439 Query: 1100 LTFEMNIPKTE 1110 FE+ +TE Sbjct: 1440 YDFELKKIRTE 1450 Score = 89.0 bits (211), Expect = 9e-16 Identities = 147/759 (19%), Positives = 322/759 (42%), Gaps = 80/759 (10%) Query: 858 LLEENQNLQISLSDMQQHYNALVEK--------------ANRTDLAESESTKYQTQLRDL 903 LLE+ +NL D+ Q + +++ AN T + S + Q Q + Sbjct: 5 LLEKGKNLTNKAKDLVQQIGSEIDQQNQAQLKGLTGQSPANSTPQNQQRSQQQQQQQQQS 64 Query: 904 ESNLKR----ITHEHQTLIVQKKKEIEDLEIEFNTQIE-SAIRDKK---------VLNEK 949 ++N + + + L++ ++++ +E + ++ S D+K +L E Sbjct: 65 QTNKNKQEDFKDQQKEKLLLDHIQQLKQIEKSLSEPLQNSTPEDQKKKITSMVNTILKEN 124 Query: 950 YEKNIEYVTQ---LEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQ 1006 K IE V Q ++ + K ENL ++ + K L+ I +V + E+ Sbjct: 125 MMKFIEKVKQQIVIKIHERVVKLIDENLGDDIPKDQKDQLKTI-FNVDYDEKDLMQQNEE 183 Query: 1007 YINEINKLNALLKQKDEEIIALN-QKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQ 1065 + N N L ++++D E + + +K N+ ++ + E+ + +L+ ++ + Sbjct: 184 F-NYDNILQLFVQKEDYETLKVQLEKSNSLYAEVRKIIEEQEAYIVVEKKELQEKQQSQE 242 Query: 1066 RVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFE--MNIPKTEGMIISSTIEPMSD 1123 ++ + L + NEE L+++ ++ +K +++ E NI K+ +S + + + + Sbjct: 243 KLIQSLQQEVKRNEE--NLIQKTNELLKTVEDNNEWQERFQNIKKS----VSDSDKLLKE 296 Query: 1124 DANNVDXXXXXXXXXXXXLK--VQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETL 1181 N V + Q+ ++ + L+ Q++ N + KI +L +L Sbjct: 297 QENIVKNLEQQLLNKSEQINQLTQQNDQLSEALKKLKAQASNENQNIDHLNKKIEELNSL 356 Query: 1182 NTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQ 1241 + V +E+ QL+ K E+ N + + + L S + V ++ +E + KQ Sbjct: 357 MQQKETEKEVAKEEKQQLQLKTEEQNKQIAEMQVQIENLNSELK--VSKQNYEESMQNKQ 414 Query: 1242 HLAQREADFQKTEHELRVQLSAFESKYEQLL---DSVQSSTQEETNKI-----VTMEQVT 1293 + + E + ++ L+ QL E+KY ++ D+ S QEE K EQ+ Sbjct: 415 NSQEIEDKLESEKNALKEQL---ENKYNEICGQKDAQISQLQEEIQKYSLEIQQLKEQLQ 471 Query: 1294 SLQNK----------LQDKEEHLRNLQEKYADVIN-QIEILRSEIEDEKVAFXXXXXXXX 1342 NK LQ + E + NL+++ V N Q EIL + ++ Sbjct: 472 QQINKEASLNDQISQLQKESEEIANLKQQLDQVQNKQNEILAQKQQEVTDLQNQLQEMTA 531 Query: 1343 XXXXXXXXDLRTENQSYKQMQE-QSILNINEENAQLKKS----SXXXXXXXXXXXXRVND 1397 L EN+++ Q+ Q ++N+ ++N +L+ + Sbjct: 532 QINEGTKKLLDQENKNHSLSQQIQELVNVQQKNIELQNQIVQLQENEQKQGQEKHSLIQK 591 Query: 1398 AEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKES 1457 E +V E+ Q E + +++ + E + + D E + + +++ +++T + S Sbjct: 592 NEHQVNEINQQKE-QITKLQAEQRELEEKVQKLKDTIEENEDMINKLKQKEQNITNDSSS 650 Query: 1458 ELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVA 1517 L ++ E H ++++ +ER ++IE+ I + L + +++ + + +E+A Sbjct: 651 LKQKLEEEIEELKRHAHEVKEQFNVERGEIIEKHKQDIQK---LQESLSKEGQGISDEIA 707 Query: 1518 KTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQK 1556 K NE +T L ++ E L I + Q ++A +I+K Sbjct: 708 KLNEERTKLSDENFE---LKQNIKDHQKDIQAKEEEIKK 743 >UniRef50_A2DD37 Cluster: Viral A-type inclusion protein, putative; n=1; Trichomonas vaginalis G3|Rep: Viral A-type inclusion protein, putative - Trichomonas vaginalis G3 Length = 1553 Score = 206 bits (502), Expect = 5e-51 Identities = 309/1431 (21%), Positives = 609/1431 (42%), Gaps = 120/1431 (8%) Query: 216 QQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLA 275 + + K N A E +D+ L + + + I + K L+A R +++ + ++L Sbjct: 117 ESLKKENANLKARIKELEDQLALLNTERDGYNSIIKDKDNQFKALQAERDDLAAKINQLT 176 Query: 276 QELEQXXXXXXXXXXXXXXLAKQSIEPSCEE----KTEIEEKGSLEIANMTELTKKIELL 331 Q+ Q ++ S+ S + K ++++K S T+L++ + + Sbjct: 177 QKC-QLNDAEKNALQAKLDSSENSLNESRNQCNFIKQQLDDKTSQCNDLGTKLSQADQTI 235 Query: 332 EHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSS 391 I Q N E++NK + ++ SK+ S + +K T K+K L + Sbjct: 236 AEKIEAINQLNNEIDNKSKIIKQYEDELAK-SKEDSEELMKKYQEET-DKLKKDSENLQN 293 Query: 392 ETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQ 451 E NQ + ++N ++ L+ ++ L D + E I + + + Sbjct: 294 ELQNQKSLAELNASDKGNLQSAVKQLQDDNSNLEKQIKVLQDDKSNLEIQREKLEQEVEE 353 Query: 452 LQLEHQQH-----MEGPSLIH-VGTNTEDVNEIAKVQEQLKQELNDEIKDVN--VKDLIE 503 L+ Q++ E L V +++ + K E L +EI ++N ++DL Sbjct: 354 LKKSQQENDEKYQKEKEDLTQTVNNQNNEISNLKKQNEDLSNSTTNEINNLNKQIQDLQN 413 Query: 504 KLKSAEEQITQLNDEIDAANKNMIKVKS-NHKLKLKQ--MQKTIDNFSK-VSDSNKEIVR 559 + E+Q N+ + N + +K N +L+ ++ +QK +N S V+D N EI Sbjct: 414 QKSDLEKQNADYNNTVSNNNDELANLKKLNQELQNEKSNLQKETENLSNTVNDKNNEIEE 473 Query: 560 LTEELHHLSQKVAELEEEKGNLQLHLVDYDSG----RMIESDVYKKMIEMENLAETRLKA 615 L ++ L + L++ K +L + D + D+ + ++E E Sbjct: 474 LKKQNEDLQNEKQNLQKVKEDLTNTITTKDDEIKDLKKQNEDLQNQNNDLEKQKEDLNNT 533 Query: 616 ISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASK 675 ++ +S+ +L + LQ+ + D DI+ L+ E K LE +ID ++A Sbjct: 534 VANKDSELNNLKNDNQQLQEANKKQND---DINNLKKSNQDLEDKVTDLEGKIDEMTAEN 590 Query: 676 KELALVIENLKLDKEQLYG----TIKDLENDKEDIMNKLQNYIQENMDLT---DKLEKMS 728 + L ++ L + L G T+ +L + + ++ + + DL D LEK Sbjct: 591 EGLMENVKTRDLQLDNLQGEHSQTVDELNQNNLSLQMQIDSLNSDVNDLKSQKDSLEKDK 650 Query: 729 AE---KISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESI 785 ++ K+ EL + E+ S + + + Q+ ++ I +EL+K ++I Sbjct: 651 SDLEKKVKELEEALEDEKNSSLLNSSNFNEESQK---LMDKI-NELTKQNRE---KNQNI 703 Query: 786 AVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIE 845 +E+ + +L++ D L L +K Y + + ELV + L++ + E+ Sbjct: 704 KKLENEKANLQQNNDNLNQRLDNVKKQYEDLQASKSELVGKYNDLVEKFNKERQTNNELS 763 Query: 846 HENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKAN--RTDLAESESTKYQTQLRDL 903 +N+ +++ Q L+ + +L+ SD+ Q YN LV K N R + A+++S Q Q++ L Sbjct: 764 QQNQAQKQQIQQLMNDLASLRDGKSDIVQKYNDLVAKFNDERQEAAKTKS-DLQNQIQQL 822 Query: 904 ESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQ 963 + L + E Q K +I + ++E +DK ++ E+ + + Q Sbjct: 823 KDALAKA--ESNQKETQNKLDISNSDLEKE-------KDK---SKSLEEELAALKSKLQQ 870 Query: 964 LQEYKNNIENLNMNVEELN-KMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKD 1022 +QE K N+E+ N + N N EL DK + K Q ++ D +N+IN+L LKQK+ Sbjct: 871 VQEEKANLESDLENERQNNSSSNAELSDK-LSKLQQENRD----LVNQINQLQNDLKQKE 925 Query: 1023 EEIIALN---QKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNE 1079 EI ++ +NN S ++D + K + + KL N+ ++ +R K L+D N Sbjct: 926 SEIQKVSSDLDNLNNVIQDLESQMNDMQGKNDELSKKLSNLVDDNERKDK-LIDDL--NS 982 Query: 1080 ELQILVREQDDQIKELKETKLTFEMNIPKTEGM--IISSTIEPMSD--DANNVDXXXXXX 1135 +L L E+D +L ET+ + E + +I +S+ D NN Sbjct: 983 QLSNLNNEKDSLTNKLSETESEKLDLANQNEKLLKVIEDLQRSLSEEKDKNNSSLLSLGD 1042 Query: 1136 XXXXXXL---KVQEEEEFI----QERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGH 1188 L KV + E+ + QE E+ +KLN +L+E I +++ +L Sbjct: 1043 FGKENALLKEKVADLEKQVSNLKQENETQNEEISKLNNDLREAADYIEKIKQQYLKLKKE 1102 Query: 1189 DVVNQEQINQLK-------SKLEQLNTENDNLLSTVAEL------RSSISSAVDQRGFE- 1234 + +E+I++LK S ++QLN + +L + EL S S ++++ E Sbjct: 1103 NQALKEEISKLKAENDEHNSTIDQLNDDKRDLEEQLKELNITLDEEKSKSFSLNENASEE 1162 Query: 1235 ------IAELWKQHL---AQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNK 1285 I + K L Q+ + + H LR Q+ ++S ++L + S+ QEE + Sbjct: 1163 LKNKDDINDGLKSQLKSQVQQNKEIEAENHNLRSQVDQYKSSNDELETQI-SNYQEENSN 1221 Query: 1286 IVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXX 1345 + + ++S +NK +D E + L++K + Q+E E E++ Sbjct: 1222 L--QDLLSSSENKNKDINEQNKQLKQK----LQQLENSLRESENKYNNLVKSNCDEITKL 1275 Query: 1346 XXXXXDLRTENQSYKQMQEQSILNINE--ENAQLKKSSXXXXXXXXXXXXRVND-AEAKV 1402 D +N Y ++ I + E N ++KS R N ++++ Sbjct: 1276 SQQLQDAMQDNAKYSSEKDNLIKKLKELNNNLNVQKSQNKQIENQRSFLERENQRLKSQI 1335 Query: 1403 LELT-HQLELKDSE-IYQKTHEYTIT---LTQRNDEFENVRQQLVEYEKRIEDLTYEKES 1457 EL+ +Q+ D E + + TI L + NDE + L ++ + E Sbjct: 1336 SELSKNQIPSVDIEDLKYQMRTLTIENEHLKKNNDEIRQRMRHLESTNAQLSIQNNQNEL 1395 Query: 1458 ELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVA 1517 +L L + + ++ ++KE+ + I+ +N K N ++E +K+ EE Sbjct: 1396 KLCTLEQRCVWLSGAHDKLRKEN-FDLSSTIDTMNSKSQYETKPNVYISEGSKSQEEYEI 1454 Query: 1518 KTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGR 1568 K E+ +E E+ N+ ++ M + + + + S A + + R Sbjct: 1455 KIRELILQIERLHKELEDKNENNNDVIRMKQTNQQLSKVNQSLALENSRLR 1505 Score = 165 bits (401), Expect = 9e-39 Identities = 252/1293 (19%), Positives = 562/1293 (43%), Gaps = 105/1293 (8%) Query: 309 EIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSK-KGS 367 E+E+ + + E K+ E L+ N ++ KELE++LA + TE +S K K + Sbjct: 97 ELEKTYGISASKFGEWMKQFESLKKENANLKARIKELEDQLALLNTERDGYNSIIKDKDN 156 Query: 368 PLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYV 427 + ++ R+ + + +QL+ + D +K + AKL+ SLN+ ++ Sbjct: 157 QFKALQAERD---DLAAKINQLTQKCQLNDAEKNALQ---AKLDSSENSLNESRNQCNFI 210 Query: 428 ---ISEKDTXXXXXXXXXXGKDTLIAQ-LQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQE 483 + +K + D IA+ ++ +Q + E + + ED E+AK +E Sbjct: 211 KQQLDDKTSQCNDLGTKLSQADQTIAEKIEAINQLNNEIDNKSKIIKQYED--ELAKSKE 268 Query: 484 QLKQELNDEIKDVNVKDLIEKLKSAEEQI-TQLNDEIDAANKNMIKVKSNHKLKLKQMQK 542 +EL + ++ +KLK E + +L ++ A N K N + +KQ+Q Sbjct: 269 D-SEELMKKYQEET-----DKLKKDSENLQNELQNQKSLAELN-ASDKGNLQSAVKQLQD 321 Query: 543 TIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKM 602 DN S+ K+I L ++ +L + +LE+E L+ + D E + + Sbjct: 322 --DN----SNLEKQIKVLQDDKSNLEIQREKLEQEVEELKKSQQENDEKYQKEKEDLTQT 375 Query: 603 IEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSV 662 + +N + LK + E E++ L ++ +++++ +D+ + +D + + Sbjct: 376 VNNQNNEISNLKKQN--EDLSNSTTNEINNLNKQIQDLQNQKSDLEKQNADYNNTVSNN- 432 Query: 663 HLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTD 722 +++ L +EL NL+ + E L T+ D N+ E++ ++N DL + Sbjct: 433 --NDELANLKKLNQELQNEKSNLQKETENLSNTVNDKNNEIEELK-------KQNEDLQN 483 Query: 723 KLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLE 782 EK + +K+ E L + +I+ D K Q DL +N ++L K K Sbjct: 484 --EKQNLQKVKEDLTNTITTKDDEIK-----DLKKQNEDL--QNQNNDLEKQK------- 527 Query: 783 ESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLL 842 ED ++ K +L + + Q+ Q D++ N L ++ +E ++ Sbjct: 528 ------EDLNNTVANKDSELNNLKNDNQQLQEANKKQNDDINN----LKKSNQDLEDKVT 577 Query: 843 EIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLA-ESESTKYQTQLR 901 ++E + E+ +N+ L+E + + L ++Q ++ V++ N+ +L+ + + + + Sbjct: 578 DLEGKIDEMTAENEGLMENVKTRDLQLDNLQGEHSQTVDELNQNNLSLQMQIDSLNSDVN 637 Query: 902 DLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLE 961 DL+S + + L +K++++LE + S++ + NE+ +K ++ + +L Sbjct: 638 DLKSQKDSLEKDKSDL----EKKVKELEEALEDEKNSSLLNSSNFNEESQKLMDKINELT 693 Query: 962 AQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQK 1021 Q +E NI+ L L + N + +++ + + Q D + K N L+++ Sbjct: 694 KQNREKNQNIKKLENEKANLQQNN-DNLNQRLDNVKKQYEDLQASKSELVGKYNDLVEKF 752 Query: 1022 DEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEEL 1081 ++E N +++ + + + LA ++ ++ + + D +Q + Sbjct: 753 NKE-RQTNNELSQQNQAQKQQIQQLMNDLASLRDGKSDIVQKYNDLVAKFNDERQEAAKT 811 Query: 1082 QILVREQDDQIKELKETKLTFEMNIPKTEGM--IISSTIEPMSDDANNVDXXXXXXXXXX 1139 + + +QI++LK+ E N +T+ I +S +E D + +++ Sbjct: 812 K---SDLQNQIQQLKDALAKAESNQKETQNKLDISNSDLEKEKDKSKSLEEELAALKSKL 868 Query: 1140 XXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQL 1199 +VQEE+ ++ S L+ + ++ E K+ +L+ N +L Q + Q Sbjct: 869 Q--QVQEEKANLE--SDLENERQNNSSSNAELSDKLSKLQQENRDLVNQINQLQNDLKQK 924 Query: 1200 KSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRV 1259 +S++++++++ DNL + + +L S ++ + + E+++ + E K +L Sbjct: 925 ESEIQKVSSDLDNLNNVIQDLESQMND-MQGKNDELSKKLSNLVDDNERK-DKLIDDLNS 982 Query: 1260 QLSAFESKYEQLLDSVQSSTQEETNKIVTMEQ----VTSLQNKLQDKEEHLRNLQEKYAD 1315 QLS ++ + L + + + E+ + E+ + LQ L ++++ + D Sbjct: 983 QLSNLNNEKDSLTNKLSETESEKLDLANQNEKLLKVIEDLQRSLSEEKDKNNSSLLSLGD 1042 Query: 1316 VINQIEILRSEIED-EKVA--FXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINE 1372 + +L+ ++ D EK DLR E Y + +Q L + + Sbjct: 1043 FGKENALLKEKVADLEKQVSNLKQENETQNEEISKLNNDLR-EAADYIEKIKQQYLKLKK 1101 Query: 1373 ENAQLKKSSXXXXXXXXXXXXRVN-------DAEAKVLELTHQLELKDSEIYQKTHEYTI 1425 EN LK+ ++ D E ++ EL L+ + S+ + + Sbjct: 1102 ENQALKEEISKLKAENDEHNSTIDQLNDDKRDLEEQLKELNITLDEEKSKSFSLNENASE 1161 Query: 1426 TLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERV 1485 L ++D + ++ QL ++ +++ E E+ ++ ++++N Q + E Sbjct: 1162 ELKNKDDINDGLKSQLKSQVQQNKEI--EAENHNLRSQVDQYKSSNDELETQISNYQEEN 1219 Query: 1486 KLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLN-DEITNLQ 1544 +++L ++ S + NK + E NK L++++ + EN+ +V N DEIT L Sbjct: 1220 SNLQDL---LSSSENKNKDINEQNKQLKQKLQQLENSLRESENKYNNLVKSNCDEITKLS 1276 Query: 1545 NMVRASSSKIQKHVSFASDTKQGRDEQLDNTMN 1577 ++ + K+ S D + ++L+N +N Sbjct: 1277 QQLQDAMQDNAKY-SSEKDNLIKKLKELNNNLN 1308 Score = 153 bits (371), Expect = 4e-35 Identities = 282/1420 (19%), Positives = 590/1420 (41%), Gaps = 134/1420 (9%) Query: 147 LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXX 206 + + +K + + L K+ + TI + E IN+ + I+ K+K Sbjct: 210 IKQQLDDKTSQCNDLGTKLSQADQTIAEKIEAINQLNNEIDNKSKIIKQYEDELAKSKED 269 Query: 207 XXXXXEDTKQQMTKMQENFIAMEAEWKDEKQ----------RLLKDIESKDVRISSLEEA 256 + +++ K++++ ++ E +++K L ++ S+LE+ Sbjct: 270 SEELMKKYQEETDKLKKDSENLQNELQNQKSLAELNASDKGNLQSAVKQLQDDNSNLEKQ 329 Query: 257 NKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIE--EKG 314 K+L+ + + ++ KL QE+E+ + + + EI +K Sbjct: 330 IKVLQDDKSNLEIQREKLEQEVEELKKSQQENDEKYQKEKEDLTQTVNNQNNEISNLKKQ 389 Query: 315 SLEIANMT-----ELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPL 369 + +++N T L K+I+ L++ + + N + N T+ + +++ K L Sbjct: 390 NEDLSNSTTNEINNLNKQIQDLQNQKSDLEKQNADYNN---TVSNNNDELANLKKLNQEL 446 Query: 370 ISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVIS 429 +N S ++ LS+ +++ + + K + L+ Q+L K D I+ Sbjct: 447 ------QNEKSNLQKETENLSNTVNDKNNEIEELKKQNEDLQNEKQNLQKVKEDLTNTIT 500 Query: 430 EKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQEL 489 KD +D LE Q+ + V ++N + +QL QE Sbjct: 501 TKD--DEIKDLKKQNEDLQNQNNDLEKQKEDLNNT---VANKDSELNNLKNDNQQL-QEA 554 Query: 490 NDEIKDVNVKDLIEKLKSAEEQITQLN---DEIDAANKNMIKVKSNHKLKLKQMQKTIDN 546 N + D ++ +L + + E+++T L DE+ A N+ +++ L+L +Q ++ Sbjct: 555 NKKQND-DINNLKKSNQDLEDKVTDLEGKIDEMTAENEGLMENVKTRDLQLDNLQG--EH 611 Query: 547 FSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEME 606 V + N+ + L ++ L+ V +L+ +K +L+ +SD+ KK+ E+E Sbjct: 612 SQTVDELNQNNLSLQMQIDSLNSDVNDLKSQKDSLEKD----------KSDLEKKVKELE 661 Query: 607 NLAETRLKAISLLESQKFDLVQELHILQQKYDEV----EDKLADISQLQSDQVCSEIKSV 662 E K SLL S F+ +E L K +E+ +K +I +L++++ + + Sbjct: 662 EALEDE-KNSSLLNSSNFN--EESQKLMDKINELTKQNREKNQNIKKLENEKANLQQNND 718 Query: 663 HLEEQID-------ALSASKKELALVIENL--KLDKEQLYGTIKDLENDKEDIMNKLQNY 713 +L +++D L ASK EL +L K +KE+ T +L + ++Q Sbjct: 719 NLNQRLDNVKKQYEDLQASKSELVGKYNDLVEKFNKER--QTNNELSQQNQAQKQQIQQL 776 Query: 714 IQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSK 773 + + L D + +K ++L+AK N E Q +T+ + +IQ+ + ES + Sbjct: 777 MNDLASLRDGKSDI-VQKYNDLVAKFNDERQEAAKTKSDLQNQIQQLKDALAKAESNQKE 835 Query: 774 YKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDH 833 ++++ + +D+ SLE + L S LQ+ Q+ E E +L N Sbjct: 836 TQNKLDISNSDLEKEKDKSKSLEEELAALKSKLQQVQE---EKANLESDLENERQNNSSS 892 Query: 834 DRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESES 893 + + +L +++ EN++L NQI +N +L+ S++Q+ + L N ES+ Sbjct: 893 NAELSDKLSKLQQENRDL--VNQINQLQN-DLKQKESEIQKVSSDLDNLNNVIQDLESQM 949 Query: 894 TKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKN 953 Q + +L L + +++ +K K I+DL N+Q+ + +K L K + Sbjct: 950 NDMQGKNDELSKKLSNLVDDNE----RKDKLIDDL----NSQLSNLNNEKDSLTNKLSET 1001 Query: 954 IEYVTQLEAQLQEYKNNIENLNMNV-EELNKMNLELID-KHVQKQQTQSPDYTEQYINEI 1011 L Q ++ IE+L ++ EE +K N L+ K+ + ++ Sbjct: 1002 ESEKLDLANQNEKLLKVIEDLQRSLSEEKDKNNSSLLSLGDFGKENALLKEKVADLEKQV 1061 Query: 1012 NKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEM-QRVSKQ 1070 + L + ++EEI LN + A +DY K+ Q KL+ + + + +SK Sbjct: 1062 SNLKQENETQNEEISKLNNDLREA--------ADYIEKIKQQYLKLKKENQALKEEISKL 1113 Query: 1071 LLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDX 1130 ++ +HN + L ++ D ++LKE +T + K+ S E S++ N D Sbjct: 1114 KAENDEHNSTIDQLNDDKRDLEEQLKELNITLDEEKSKS-----FSLNENASEELKNKDD 1168 Query: 1131 XXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDV 1190 +VQ+ +E E L+ Q + + E T+I + N+ L Sbjct: 1169 INDGLKSQLKS-QVQQNKEIEAENHNLRSQVDQYKSSNDELETQISNYQEENSNL----- 1222 Query: 1191 VNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREAD- 1249 Q+ ++ ++K + +N +N L + +L +S+ + ++ +L + D Sbjct: 1223 --QDLLSSSENKNKDINEQNKQLKQKLQQLENSLRESENK---------YNNLVKSNCDE 1271 Query: 1250 FQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKI-VTMEQVTSLQNKLQDKEEHLRN 1308 K +L+ + +KY D++ +E N + V Q ++N+ E + Sbjct: 1272 ITKLSQQLQDAMQD-NAKYSSEKDNLIKKLKELNNNLNVQKSQNKQIENQRSFLERENQR 1330 Query: 1309 LQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSIL 1368 L+ + ++ +++ +I +IED K ++R + + Q L Sbjct: 1331 LKSQISE-LSKNQIPSVDIEDLKYQM-RTLTIENEHLKKNNDEIRQRMRHLESTNAQ--L 1386 Query: 1369 NINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLT 1428 +I +LK + E L T S+ K + Y + Sbjct: 1387 SIQNNQNELKLCTLEQRCVWLSGAHDKLRKENFDLSSTIDTMNSKSQYETKPNVYISEGS 1446 Query: 1429 QRNDEFE-NVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKL 1487 + +E+E +R+ +++ E+ ++L + E+ ++R+K +T Q+ S++ + Sbjct: 1447 KSQEEYEIKIRELILQIERLHKELEDKNENNNDVIRMK--------QTNQQLSKVNQSLA 1498 Query: 1488 IEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALE 1527 +E ++ NK ++ + VA NE Q E Sbjct: 1499 LENSRLRFWLECEKNKS----HRLSDSYVAVKNENQRLFE 1534 Score = 144 bits (350), Expect = 1e-32 Identities = 231/1105 (20%), Positives = 472/1105 (42%), Gaps = 90/1105 (8%) Query: 143 DVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXX 202 + +LSNT+ +K+N + L+ + + ++ +LQ+ + I K+ Sbjct: 456 ETENLSNTVNDKNNEIEELKKQNEDLQNEKQNLQKVKEDLTNTITTKDD-EIKDLKKQNE 514 Query: 203 XXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEA 262 E K+ + N + K++ Q+L + + ++ I++L+++N+ LE Sbjct: 515 DLQNQNNDLEKQKEDLNNTVANKDSELNNLKNDNQQLQEANKKQNDDINNLKKSNQDLED 574 Query: 263 ARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLA---KQSIEPSCEEKTEIEEKGSLEIA 319 ++ + ++ E E L Q+++ + ++ + + Sbjct: 575 KVTDLEGKIDEMTAENEGLMENVKTRDLQLDNLQGEHSQTVDELNQNNLSLQMQIDSLNS 634 Query: 320 NMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTA 379 ++ +L + + LE + + KELE L +K S L++ + + Sbjct: 635 DVNDLKSQKDSLEKDKSDLEKKVKELEEAL------------EDEKNSSLLNSSNFNEES 682 Query: 380 SKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNK--DLVDKEYVISEKDTXXXX 437 K+ ++L+ + ++ + K +NE A L+ +LN+ D V K+Y +D Sbjct: 683 QKLMDKINELTKQNREKNQNIKKLENEKANLQQNNDNLNQRLDNVKKQY----EDLQASK 738 Query: 438 XXXXXXGKDTLIAQLQLEHQQHME--GPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKD 495 D L+ + E Q + E + + +N++A +++ K ++ + D Sbjct: 739 SELVGKYND-LVEKFNKERQTNNELSQQNQAQKQQIQQLMNDLASLRDG-KSDIVQKYND 796 Query: 496 VNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNK 555 + K E+ ++A+ + + L ++I + K +SN K ++ + + K D +K Sbjct: 797 LVAKFNDERQEAAKTK-SDLQNQIQQLKDALAKAESNQKETQNKLDISNSDLEKEKDKSK 855 Query: 556 EIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKA 615 L EEL L K+ +++EEK NL+ D ++ R S ++ + Sbjct: 856 S---LEEELAALKSKLQQVQEEKANLE---SDLENERQNNSSSNAELSD----------K 899 Query: 616 ISLLESQKFDLVQELHILQ----QKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDAL 671 +S L+ + DLV +++ LQ QK E++ +D+ L + V +++S + Q Sbjct: 900 LSKLQQENRDLVNQINQLQNDLKQKESEIQKVSSDLDNL--NNVIQDLESQMNDMQGKND 957 Query: 672 SASKKELALVIENLKLDK--EQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSA 729 SKK LV +N + DK + L + +L N+K+ + NKL E +DL ++ EK+ Sbjct: 958 ELSKKLSNLVDDNERKDKLIDDLNSQLSNLNNEKDSLTNKLSETESEKLDLANQNEKL-L 1016 Query: 730 EKISELLAKINHEEQSKIQTQFGIDAKIQERDLY---IENIESELSKYKSRICRLEESIA 786 + I +L ++ E+ + + +E L + ++E ++S K E I+ Sbjct: 1017 KVIEDLQRSLSEEKDKNNSSLLSLGDFGKENALLKEKVADLEKQVSNLKQENETQNEEIS 1076 Query: 787 VMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEH 846 + + L AD + Q+ K E ++E+ A +H+ ++ QL + + Sbjct: 1077 KLNN---DLREAADYIEKIKQQYLKLKKENQALKEEISKLKAENDEHNSTID-QLNDDKR 1132 Query: 847 ENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESN 906 + +E K+ I L+E ++ SL++ NA E N+ D+ + ++ ++Q++ Sbjct: 1133 DLEEQLKELNITLDEEKSKSFSLNE-----NASEELKNKDDINDGLKSQLKSQVQQ-NKE 1186 Query: 907 LKRITHEHQTLIVQKKKEIEDLEIEFNTQIE--SAIRDKKVLNEKYEKNI-EYVTQLEAQ 963 ++ H ++ + Q K ++LE + + E S ++D +E K+I E QL+ + Sbjct: 1187 IEAENHNLRSQVDQYKSSNDELETQISNYQEENSNLQDLLSSSENKNKDINEQNKQLKQK 1246 Query: 964 LQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPD---YTEQYINEINKL----NA 1016 LQ+ +N++ L K N + I K Q+ Q D Y+ + N I KL N Sbjct: 1247 LQQLENSLRESENKYNNLVKSNCDEITKLSQQLQDAMQDNAKYSSEKDNLIKKLKELNNN 1306 Query: 1017 LLKQKDEEIIALNQK--INNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDS 1074 L QK + NQ+ + S +S+ SK + +E+++ +M+ ++ + Sbjct: 1307 LNVQKSQNKQIENQRSFLERENQRLKSQISEL-SKNQIPSVDIEDLKYQMRTLTIENEHL 1365 Query: 1075 KQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXX 1134 K++N+E++ +R + +L E+ + E + + N D Sbjct: 1366 KKNNDEIRQRMRHLESTNAQLSIQNNQNELKLCTLEQRCVWLSGAHDKLRKENFDLSSTI 1425 Query: 1135 XXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTEL-----TGHD 1189 + +I E S QE+ EL I+Q+E L+ EL +D Sbjct: 1426 DTMNSKSQYETKPNVYISEGSKSQEEYEIKIREL------ILQIERLHKELEDKNENNND 1479 Query: 1190 VVNQEQINQLKSKLEQ-LNTENDNL 1213 V+ +Q NQ SK+ Q L EN L Sbjct: 1480 VIRMKQTNQQLSKVNQSLALENSRL 1504 Score = 130 bits (315), Expect = 2e-28 Identities = 197/956 (20%), Positives = 403/956 (42%), Gaps = 115/956 (12%) Query: 699 LENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDA-KI 757 LEN ++ N+ + + ++N LTD+ M +K+ EL + +GI A K Sbjct: 63 LENKNTNLSNESKMFARQNKALTDE-NNMLKKKLGEL------------EKTYGISASKF 109 Query: 758 QERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYT 817 E E+++ E + K+RI LE+ +A++ R D S +++K + Sbjct: 110 GEWMKQFESLKKENANLKARIKELEDQLALLNTER-------DGYNSIIKDKDNQFKALQ 162 Query: 818 IQEDELVNRLAVLMDHDRV--VEKQLLEIE---HENKELQKKNQILLEENQ--------- 863 + D+L ++ L ++ EK L+ + EN + +NQ + Q Sbjct: 163 AERDDLAAKINQLTQKCQLNDAEKNALQAKLDSSENSLNESRNQCNFIKQQLDDKTSQCN 222 Query: 864 NLQISLSDMQQHYNALVEKANRTDLAESESTK----YQTQLRDLESNLKRITHEHQTLIV 919 +L LS Q +E N+ + +K Y+ +L + + + + ++Q Sbjct: 223 DLGTKLSQADQTIAEKIEAINQLNNEIDNKSKIIKQYEDELAKSKEDSEELMKKYQEETD 282 Query: 920 QKKKEIEDLEIEFNTQ---IESAIRDKKVLNEKYEKNIEYVTQLEAQ---LQEYKNNI-- 971 + KK+ E+L+ E Q E DK L ++ + + LE Q LQ+ K+N+ Sbjct: 283 KLKKDSENLQNELQNQKSLAELNASDKGNLQSAVKQLQDDNSNLEKQIKVLQDDKSNLEI 342 Query: 972 --ENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALN 1029 E L VEEL K E + +K Q + D T+ N+ N+++ L KQ ++ + Sbjct: 343 QREKLEQEVEELKKSQQE----NDEKYQKEKEDLTQTVNNQNNEISNLKKQNEDLSNSTT 398 Query: 1030 QKIN--NAQV-SYMSMVSDYESKLAQFTTKLENMEEEMQRVSK--QLLDSKQHN-----E 1079 +IN N Q+ + SD E + A + + N +E+ + K Q L +++ N E Sbjct: 399 NEINNLNKQIQDLQNQKSDLEKQNADYNNTVSNNNDELANLKKLNQELQNEKSNLQKETE 458 Query: 1080 ELQILVREQDDQIKELK---ETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXX 1136 L V +++++I+ELK E + N+ K + +++TI D+ ++ Sbjct: 459 NLSNTVNDKNNEIEELKKQNEDLQNEKQNLQKVK-EDLTNTITTKDDEIKDLKKQNEDLQ 517 Query: 1137 XXXXXLKVQEEE-------------EFIQERSVLQEQSAKLNTEL-------QECYTKII 1176 L+ Q+E+ + LQE + K N ++ Q+ K+ Sbjct: 518 NQNNDLEKQKEDLNNTVANKDSELNNLKNDNQQLQEANKKQNDDINNLKKSNQDLEDKVT 577 Query: 1177 QLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIA 1236 LE E+T + E + +L+ L E+ + + + S+ +D ++ Sbjct: 578 DLEGKIDEMTAENEGLMENVKTRDLQLDNLQGEHSQTVDELNQNNLSLQMQIDSLNSDVN 637 Query: 1237 EL--WKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTS 1294 +L K L + ++D +K EL L + K LL+S S+ EE+ K+ M+++ Sbjct: 638 DLKSQKDSLEKDKSDLEKKVKELEEALE--DEKNSSLLNS--SNFNEESQKL--MDKINE 691 Query: 1295 LQNKLQDKEEHLRNLQEKYA------DVINQ-IEILRSEIEDEKVAFXXXXXXXXXXXXX 1347 L + ++K ++++ L+ + A D +NQ ++ ++ + ED + + Sbjct: 692 LTKQNREKNQNIKKLENEKANLQQNNDNLNQRLDNVKKQYEDLQASKSELVGKYNDLVEK 751 Query: 1348 XXXDLRTENQ--SYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLEL 1405 + +T N+ Q Q+Q I + + A L+ + ND + + Sbjct: 752 FNKERQTNNELSQQNQAQKQQIQQLMNDLASLRDGKSDIVQKYNDLVAKFNDERQEAAKT 811 Query: 1406 THQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLK 1465 L+ + ++ + + ++ + + +E EK D + E ELA L+ K Sbjct: 812 KSDLQNQIQQLKDALAKAESNQKETQNKLD-ISNSDLEKEK---DKSKSLEEELAALKSK 867 Query: 1466 MHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTA 1525 + + ++ + E ER + + L+ ++++L + + V + N++Q Sbjct: 868 LQQVQEEKANLESDLENERQN-------NSSSNAELSDKLSKLQQENRDLVNQINQLQND 920 Query: 1526 LENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELL 1581 L+ +E EI ++ ++ NL N+++ S++ + + +D+ K+ L Sbjct: 921 LKQKESEIQKVSSDLDNLNNVIQDLESQMNDMQGKNDELSKKLSNLVDDNERKDKL 976 Score = 111 bits (267), Expect = 2e-22 Identities = 165/834 (19%), Positives = 357/834 (42%), Gaps = 83/834 (9%) Query: 771 LSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVL 830 +S ++ L++ + + +L + +L S + E +K + EL + L Sbjct: 1 MSASDPKVQELQQKVNKLTTANETLNNENLKLKSQVVEYEKGNTPMVAVRKELDD----L 56 Query: 831 MDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEK----ANRT 886 + +E + + +E+K ++N+ L +EN L+ L ++++ Y K + Sbjct: 57 KNKYSFLENKNTNLSNESKMFARQNKALTDENNMLKKKLGELEKTYGISASKFGEWMKQF 116 Query: 887 DLAESESTKYQTQLRDLESNLKRITHE---HQTLIVQKKKEIEDLEIEFNTQIESAIRDK 943 + + E+ + ++++LE L + E + ++I K + + L+ E + + I Sbjct: 117 ESLKKENANLKARIKELEDQLALLNTERDGYNSIIKDKDNQFKALQAE-RDDLAAKINQ- 174 Query: 944 KVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDY 1003 L +K + N L+A+L +N +LN + + N + +L DK +Q D Sbjct: 175 --LTQKCQLNDAEKNALQAKLDSSEN---SLNESRNQCNFIKQQLDDK-----TSQCNDL 224 Query: 1004 TEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEE 1063 ++++ + + +K E I LN +I+N ++ YE +LA+ E+ EE Sbjct: 225 G----TKLSQADQTIAEKIEAINQLNNEIDNKS----KIIKQYEDELAK---SKEDSEEL 273 Query: 1064 MQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSD 1123 M K++ EE L ++ ++ EL+ K E+N ++ + S ++ + D Sbjct: 274 M----------KKYQEETDKLKKDSENLQNELQNQKSLAELN--ASDKGNLQSAVKQLQD 321 Query: 1124 DANNVDXXXXXXXXXXXXLKVQEE--EEFIQERSVLQEQSAKLNTELQECYTKIIQLETL 1181 D +N++ L++Q E E+ ++E Q+++ + + +E T+ + + Sbjct: 322 DNSNLEKQIKVLQDDKSNLEIQREKLEQEVEELKKSQQENDEKYQKEKEDLTQTVNNQ-- 379 Query: 1182 NTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAEL---RSSISSAVDQRGFEIAEL 1238 N E++ N++ N +++ LN + +L + ++L + ++ V E+A L Sbjct: 380 NNEISNLKKQNEDLSNSTTNEINNLNKQIQDLQNQKSDLEKQNADYNNTVSNNNDELANL 439 Query: 1239 WK--QHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQ 1296 K Q L +++ QK L ++ ++ E+L + E+ N E +T Sbjct: 440 KKLNQELQNEKSNLQKETENLSNTVNDKNNEIEELKKQNEDLQNEKQNLQKVKEDLT--- 496 Query: 1297 NKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTEN 1356 N + K++ +++L+++ D+ NQ L + ED +L+ +N Sbjct: 497 NTITTKDDEIKDLKKQNEDLQNQNNDLEKQKED--------LNNTVANKDSELNNLKNDN 548 Query: 1357 QSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEI 1416 Q Q+QE + N++ LKKS+ ++++ A+ L ++ +D ++ Sbjct: 549 Q---QLQEAN-KKQNDDINNLKKSNQDLEDKVTDLEGKIDEMTAENEGLMENVKTRDLQL 604 Query: 1417 YQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKES---ELAILRLKMHENANHY 1473 E++ T+ + N +++ Q+ + DL +K+S + + L K+ E Sbjct: 605 DNLQGEHSQTVDELNQNNLSLQMQIDSLNSDVNDLKSQKDSLEKDKSDLEKKVKELEEAL 664 Query: 1474 ETMQKESEIERVKLIEE---LNVKITESVSLNKQVAELNKALEEEVA----KTNEMQTAL 1526 E + S + EE L KI E N++ + K LE E A + + L Sbjct: 665 EDEKNSSLLNSSNFNEESQKLMDKINELTKQNREKNQNIKKLENEKANLQQNNDNLNQRL 724 Query: 1527 EN---QEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMN 1577 +N Q ++ E+ N + +K ++ + S Q + +Q+ MN Sbjct: 725 DNVKKQYEDLQASKSELVGKYNDLVEKFNKERQTNNELSQQNQAQKQQIQQLMN 778 Score = 61.3 bits (142), Expect = 2e-07 Identities = 106/592 (17%), Positives = 238/592 (40%), Gaps = 38/592 (6%) Query: 141 LGDVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXX 200 + + L N +K+K++ + + + + I DL+ ++N+ ++ KN + Sbjct: 911 VNQINQLQNDLKQKESEIQKVSSDLDNLNNVIQDLESQMND----MQGKNDELSKKLSNL 966 Query: 201 XXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSL-EEANKL 259 +D Q++ + KD L + ES+ + +++ E+ K+ Sbjct: 967 VDDNERKDKLIDDLNSQLSNLNNE--------KDSLTNKLSETESEKLDLANQNEKLLKV 1018 Query: 260 LEAARFEISLEHSK---LAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSL 316 +E + +S E K L L KQ E +T+ EE L Sbjct: 1019 IEDLQRSLSEEKDKNNSSLLSLGDFGKENALLKEKVADLEKQVSNLKQENETQNEEISKL 1078 Query: 317 EIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGR 376 ++ E IE ++ ++++ N+ L+ +++ + E+ +S + + + Sbjct: 1079 N-NDLREAADYIEKIKQQYLKLKKENQALKEEISKLKAENDEHNSTIDQLNDDKRDLEEQ 1137 Query: 377 NTASKMKSPWSQLSSETLNQDTDKKI-NKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXX 435 + + S +LN++ +++ NK++I + + L + + + +E Sbjct: 1138 LKELNITLDEEKSKSFSLNENASEELKNKDDIN--DGLKSQLKSQVQQNKEIEAENHNLR 1195 Query: 436 XXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTN-TEDVNEIAKVQEQLKQELNDEIK 494 D L Q+ +++ L+ N +D+NE K +Q Q+L + ++ Sbjct: 1196 SQVDQYKSSNDELETQISNYQEENSNLQDLLSSSENKNKDINEQNKQLKQKLQQLENSLR 1255 Query: 495 DVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSN 554 + K +KS ++IT+L+ ++ A ++ K S +K++++ +N + N Sbjct: 1256 ESENK-YNNLVKSNCDEITKLSQQLQDAMQDNAKYSSEKDNLIKKLKELNNNLNVQKSQN 1314 Query: 555 KEIVR----LTEELHHLSQKVAELEEEK-GNLQLHLVDYDSGRM-IESDVYKKMIE---- 604 K+I L E L +++EL + + ++ + + Y + IE++ KK + Sbjct: 1315 KQIENQRSFLERENQRLKSQISELSKNQIPSVDIEDLKYQMRTLTIENEHLKKNNDEIRQ 1374 Query: 605 -MENLAETRLKAISLLESQK----FDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEI 659 M +L T + +S+ +Q L Q L +D++ + D+S Sbjct: 1375 RMRHLESTNAQ-LSIQNNQNELKLCTLEQRCVWLSGAHDKLRKENFDLSSTIDTMNSKSQ 1433 Query: 660 KSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQ 711 I S S++E + I L L E+L+ ++D + D++ Q Sbjct: 1434 YETKPNVYISEGSKSQEEYEIKIRELILQIERLHKELEDKNENNNDVIRMKQ 1485 >UniRef50_A2F531 Cluster: Viral A-type inclusion protein, putative; n=1; Trichomonas vaginalis G3|Rep: Viral A-type inclusion protein, putative - Trichomonas vaginalis G3 Length = 3748 Score = 205 bits (501), Expect = 7e-51 Identities = 298/1502 (19%), Positives = 650/1502 (43%), Gaps = 129/1502 (8%) Query: 152 KEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKA--TTXXXXXXXXXXXXXXX 209 K K V K KI E I LQE +E+ QI + K++ TT Sbjct: 309 KLKKQIAKVESEKTKI-EDEIKHLQE--DEEPQIKKLKDRLDETTTKTQIAEKKLGEMRK 365 Query: 210 XXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISL 269 ED++Q++ + ++N I E ++ + +++S + +I ++ L ++ Sbjct: 366 TIEDSRQKLAQRRQNLIERRKELTNDAENTNTELQSINNQIQEIDSEFNKLNGLVNKVQS 425 Query: 270 EHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIE 329 +HSK L++ LA++ + + ++ + EEK S E A + ++ +++ Sbjct: 426 DHSKKKSALQEQ-------------LAQKQKDLNDLKRKQAEEKASRE-AEIAKINDQLQ 471 Query: 330 -LLEHLNCQIRQTNKELENKLATMGTESKAVSSP-SKKGSPLISRKSGR-----NTASKM 382 ++ N + N +L+N++ + K + S +KK L + + R ++ Sbjct: 472 KTMKEYNDLNQPQNVDLKNEIDQATKDLKELESRVNKKREELFGKNNQRVAELNKLNEQL 531 Query: 383 KSPWSQL---SSETLNQDTDKKINKNEI-AKLEMVIQSLNK--------------DLVDK 424 KS ++ E + + + KNE+ A++E V ++K DL D+ Sbjct: 532 KSKMDEMVKADQELQSAKDEHEAKKNELKAEIESVSDEISKLKDELEVIPDFEVDDLKDQ 591 Query: 425 -EYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDV---NEIAK 480 ++ EK+ ++ I L+ E Q+ I N D +E +K Sbjct: 592 LNELLKEKEELEKEKIKNNDELNSSIIMLKDEIQKEKANKDKISEEKNKRDKELNDEKSK 651 Query: 481 VQEQLKQELNDEIKDVN------VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHK 534 +Q++L DEI++ N V+DL K+ A+ + D+ID + KV+ +K Sbjct: 652 LQDELDSLQLDEIENENDQLFEEVEDLKSKVDDAKILYNDMVDKIDDLKQQRSKVEQKYK 711 Query: 535 LKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLV-DYDSGRM 593 KQ ++ D KVS E+ + L+ EL ++ + +V Sbjct: 712 DLEKQNKEKSDEIEKVSKEISELKEKLDNLNQFKDNTPELHQKVDAMNEQIVKKSQENEK 771 Query: 594 IESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSD 653 I+ ++ K E+++L E ++ I ++ ++ + +++ ++Q+ +E + +I + + Sbjct: 772 IQEEMNKLNEELQHL-ENEMEEIEVVNDERETIQEKIDNIKQQIEEKKKSNEEIQDIMNL 830 Query: 654 QVCSEIKSVHLEEQIDALSASKKELALVIENLK---LDKEQLYGTIKDLENDKEDIMNKL 710 + +E + + I+ + A +E+ I+ L+ D+++L + + N + + L Sbjct: 831 LIEAENDAQKELDDIEIVEAQSEEIRQRIQTLQDNLQDRKKLNNELTEQNNKLQKELKDL 890 Query: 711 QNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLY------I 764 QN + + + D E ++ +K+ E+ +IN + + I+E + + I Sbjct: 891 QNELDQTELVNDDSESLN-KKLDEIKEQINERKSQNENNTEQNEKLIEEIEKFAKELDEI 949 Query: 765 ENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQ-EKQKA--------YSE 815 E IE + K +++I L++ I + ++ + L LQ KQK S+ Sbjct: 950 EIIEDKSDKLQAQISELQKQIDEKQKNNEQTDKSNNDLEHELQITKQKLDSMSSVKNNSD 1009 Query: 816 YTIQEDELVNR-LAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQ 874 Y E E VN+ + + D + +++ E++ +NKEL++ I + ++ L+ + + + Sbjct: 1010 YLKSEIENVNKEIEKIRDTNNKLKQ---ELQDKNKELEEMTDI-ADNSEELKEKIDSVNE 1065 Query: 875 HYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITH-EHQTLIVQKKKEIEDLEIEFN 933 V AN T + E ++ L++ E+ L+ I H + T +QK + +I Sbjct: 1066 EITKRV--ANNTTIDELIRHLHE-DLKNAEAKLQSIPHVDDNTDSLQKSLDEVLAQISQK 1122 Query: 934 TQIESAIRDK--KVLNEKYEKNIEY--VTQLEAQLQEYKNNIENLNMNVEELNKMNLELI 989 + + D+ +++ EK EK E + + + +E + IE + +EE K N ++ Sbjct: 1123 QRENDELNDEISRLIQEKEEKTDELNNMETIPDKREEISSEIETVKSQIEEKKKNNEKIA 1182 Query: 990 DKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESK 1049 +++ K+ + + Q ++++ + L+ +EI Q+I+ Q + + E Sbjct: 1183 EEN--KKLAEELENLRQTLSKMETSDQPLENIQKEIETTKQEISEKQKELDELKQELEQI 1240 Query: 1050 LAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKE-LKETKLTFEMNIPK 1108 + +K + + EE++ + Q+ + + NEE+ E+ ++ E LKE + ++ K Sbjct: 1241 KDEDQSKADEISEEIENIKTQIDEKNKKNEEIAKNNEEKQSELDEKLKELQ---DLEEIK 1297 Query: 1109 TEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXL-KVQEEEEFIQERSVLQEQSAKLNTE 1167 E I+ IE + L K++++ E I+ +++ KL E Sbjct: 1298 DETEEINQQIEETQKEIETKKQQKENNNKLNEELDKLKQDLEQIEN---VEDNVEKLTEE 1354 Query: 1168 LQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQL---NTENDNLLSTVAELRSSI 1224 +++ + I LN ++ + V +E++N LK +LE++ ++D + + +++ I Sbjct: 1355 IEKVKSDIDSKHQLNNDIKEANEVVEEELNSLKEELEKIEPVEDKSDEIRKEIVKIQKEI 1414 Query: 1225 SS--AVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEE 1282 + A + E EL + L + ++ E + +++ E L S++ + Sbjct: 1415 ETKKATNCGISESNELLNKELNDLKNQLEEIAEE-KDDSEEIKAEIENLHKSIEEKKEHN 1473 Query: 1283 TNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXX 1342 N E + +KLQ++ + + +++K ++ ++IE L+S+IE++ Sbjct: 1474 ANTQQNNENMKEELSKLQEEFDQIEVVEDKAEEIHSEIEKLKSQIEEKN----TTNNDIK 1529 Query: 1343 XXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKV 1402 +L + Y ++ + + +EE +Q + + Sbjct: 1530 EANDILNEELNNLQKQYDEIDVEE--DKSEELSQKVTDLQKLLEEKKSQNETIKSGNENI 1587 Query: 1403 LELTHQL--ELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELA 1460 L+ L EL + E+ + E + + E ++Q + + +K+ E+ T K +E Sbjct: 1588 LKELQSLQNELDNIEVVSSSSE------EGEKKIEKLKQMISDKQKQNEETT--KHNEEL 1639 Query: 1461 ILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTN 1520 ++K EN + K+ + + IEE+ KIT+ N++ ++LN AL+EE + Sbjct: 1640 DNQIKDLENELNEIIPVKDKSNDLQQQIEEIKDKITDKQKKNEECSQLNTALKEEY---D 1696 Query: 1521 EMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRD--EQLDNTMNK 1578 ++++ +N I + + +Q + S+I + D K+G D E+ K Sbjct: 1697 QLKSEFDN----IAVIESKAEEIQQKIDEIKSEIDQKRKEYQDIKEGNDLLEEAYTEKQK 1752 Query: 1579 EL 1580 EL Sbjct: 1753 EL 1754 Score = 201 bits (490), Expect = 1e-49 Identities = 317/1509 (21%), Positives = 672/1509 (44%), Gaps = 186/1509 (12%) Query: 230 AEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEIS--LEHSKLAQELE-----QXX 282 A K + L K ++ KD I +L+ A L + E+S +E EL+ Sbjct: 181 ARSKVQMDSLRKQLQDKDEEIKNLKAATDLSNSRISELSGIIEGESKLSELKTPPSSPSY 240 Query: 283 XXXXXXXXXXXXLAKQSIEPSCEEKTEIE-EKGSLEIANMTELTKKIEL-------LEHL 334 KQ + + +TEIE E+G E N + L + I+L L+ L Sbjct: 241 RNFIDRGNYKDRRMKQLKDQLDQTETEIENEEGKTENLNYS-LNEMIDLVAERRRALQEL 299 Query: 335 NCQIRQTNKELENKLATMGTESKAVSSPSK----KGSPLISRKSGR--NTASKMKSPWSQ 388 + ++L+ ++A + +E + K P I + R T +K + + Sbjct: 300 RNSQGKDEEKLKKQIAKVESEKTKIEDEIKHLQEDEEPQIKKLKDRLDETTTKTQIAEKK 359 Query: 389 L---------SSETLNQDTDKKINK-----NEIAKLEMVIQSLNKDLVDKEYVISEKDTX 434 L S + L Q I + N+ +QS+N + + + ++ + Sbjct: 360 LGEMRKTIEDSRQKLAQRRQNLIERRKELTNDAENTNTELQSINNQIQEIDSEFNKLNGL 419 Query: 435 XXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLK---QELND 491 K + + + + Q+ + EIAK+ +QL+ +E ND Sbjct: 420 VNKVQSDHSKKKSALQEQLAQKQKDLNDLKRKQAEEKASREAEIAKINDQLQKTMKEYND 479 Query: 492 --EIKDVNVKDLIEK----LKSAEEQITQLNDEIDAANKNMI----KVKSNHKLKLKQMQ 541 + ++V++K+ I++ LK E ++ + +E+ N + K+ K K+ +M Sbjct: 480 LNQPQNVDLKNEIDQATKDLKELESRVNKKREELFGKNNQRVAELNKLNEQLKSKMDEMV 539 Query: 542 KTIDNFSKVSDSNK-EIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYK 600 K D ++ + L E+ +S ++++L++E L++ + D++ ++ + + Sbjct: 540 KADQELQSAKDEHEAKKNELKAEIESVSDEISKLKDE---LEV-IPDFEVDD-LKDQLNE 594 Query: 601 KMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEV-EDKLADISQL--QSDQVCS 657 + E E L + ++K L S L E+ + D++ E+K +L + ++ Sbjct: 595 LLKEKEELEKEKIKNNDELNSSIIMLKDEIQKEKANKDKISEEKNKRDKELNDEKSKLQD 654 Query: 658 EIKSVHLEE---QIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYI 714 E+ S+ L+E + D L ++L +++ K+ + I DL+ + + K ++ Sbjct: 655 ELDSLQLDEIENENDQLFEEVEDLKSKVDDAKILYNDMVDKIDDLKQQRSKVEQKYKDLE 714 Query: 715 QENMDLTDKLEKMSAEKISELLAKINHEEQSKIQT---QFGIDA---KIQERDLYIENIE 768 ++N + +D++EK+S E ISEL K+++ Q K T +DA +I ++ E I+ Sbjct: 715 KQNKEKSDEIEKVSKE-ISELKEKLDNLNQFKDNTPELHQKVDAMNEQIVKKSQENEKIQ 773 Query: 769 SELSKYKSRICRLE---ESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELV- 824 E++K + LE E I V+ D R +++ K D + ++EK+K+ E + L+ Sbjct: 774 EEMNKLNEELQHLENEMEEIEVVNDERETIQEKIDNIKQQIEEKKKSNEEIQDIMNLLIE 833 Query: 825 --NRLAVLMDHDRVVEKQLLEIEHENKELQ-------KKNQILLEENQNLQISLSDMQQH 875 N +D +VE Q EI + LQ K N L E+N LQ L D+Q Sbjct: 834 AENDAQKELDDIEIVEAQSEEIRQRIQTLQDNLQDRKKLNNELTEQNNKLQKELKDLQNE 893 Query: 876 YNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLI--VQK-KKEIEDLEI-- 930 + + ++ + + + Q+ + +S + T +++ LI ++K KE++++EI Sbjct: 894 LDQTELVNDDSESLNKKLDEIKEQINERKSQNENNTEQNEKLIEEIEKFAKELDEIEIIE 953 Query: 931 ----EFNTQI---ESAIRDKKVLNEKYEK---NIEYVTQLEAQ----LQEYKNN------ 970 + QI + I +K+ NE+ +K ++E+ Q+ Q + KNN Sbjct: 954 DKSDKLQAQISELQKQIDEKQKNNEQTDKSNNDLEHELQITKQKLDSMSSVKNNSDYLKS 1013 Query: 971 -IENLNMNVEEL----NKMNLELIDKHVQ-KQQTQSPDYTEQYINEINKLNALLKQK--- 1021 IEN+N +E++ NK+ EL DK+ + ++ T D +E+ +I+ +N + ++ Sbjct: 1014 EIENVNKEIEKIRDTNNKLKQELQDKNKELEEMTDIADNSEELKEKIDSVNEEITKRVAN 1073 Query: 1022 ----DEEIIALNQKINNAQVSYMSM--VSDYESKLAQFTTKLENMEEEMQRVSKQLLDSK 1075 DE I L++ + NA+ S+ V D L ++++E + ++S++ ++ Sbjct: 1074 NTTIDELIRHLHEDLKNAEAKLQSIPHVDDNTDSLQ------KSLDEVLAQISQKQREND 1127 Query: 1076 QHNEELQILVREQDDQIKELKETKLTFEMNIP-KTEGMIISSTIEPMSDDANNVDXXXXX 1134 + N+E+ L++E++++ EL + IP K E ISS IE + Sbjct: 1128 ELNDEISRLIQEKEEKTDELNNME-----TIPDKREE--ISSEIETVKSQIEE------- 1173 Query: 1135 XXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTEL--TGHDV-V 1191 K + E+ +E L E+ L L + T LE + E+ T ++ Sbjct: 1174 --------KKKNNEKIAEENKKLAEELENLRQTLSKMETSDQPLENIQKEIETTKQEISE 1225 Query: 1192 NQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQ 1251 Q+++++LK +LEQ+ E+ + ++E +I + +D++ + E+ K + +++++ Sbjct: 1226 KQKELDELKQELEQIKDEDQSKADEISEEIENIKTQIDEKNKKNEEIAKNN-EEKQSELD 1284 Query: 1252 KTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQ---NKLQDKEEHLRN 1308 + EL+ L + + E++ ++ + +E K E L +KL+ E + N Sbjct: 1285 EKLKELQ-DLEEIKDETEEINQQIEETQKEIETKKQQKENNNKLNEELDKLKQDLEQIEN 1343 Query: 1309 LQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQS-- 1366 +++ + +IE ++S+I D K L+ E + + ++++S Sbjct: 1344 VEDNVEKLTEEIEKVKSDI-DSKHQLNNDIKEANEVVEEELNSLKEELEKIEPVEDKSDE 1402 Query: 1367 ----ILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLEL------THQLELKDSEI 1416 I+ I +E K ++ +ND + ++ E+ + +++ + + Sbjct: 1403 IRKEIVKIQKEIETKKATNCGISESNELLNKELNDLKNQLEEIAEEKDDSEEIKAEIENL 1462 Query: 1417 YQKTHEYTITLTQRNDEFENVRQQLVEYEKR------IEDLTYEKESELAILRLKMHENA 1470 ++ E EN++++L + ++ +ED E SE+ L+ ++ E Sbjct: 1463 HKSIEEKKEHNANTQQNNENMKEELSKLQEEFDQIEVVEDKAEEIHSEIEKLKSQIEEKN 1522 Query: 1471 NHYETMQKESEI--ERV----KLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQT 1524 +++ ++I E + K +E++V+ +S L+++V +L K LEE+ ++ +++ Sbjct: 1523 TTNNDIKEANDILNEELNNLQKQYDEIDVEEDKSEELSQKVTDLQKLLEEKKSQNETIKS 1582 Query: 1525 ALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTM--NKELLD 1582 EN E+ +L +E+ N++ +V +SS + +K + + +Q + T N+EL + Sbjct: 1583 GNENILKELQSLQNELDNIE-VVSSSSEEGEKKIEKLKQMISDKQKQNEETTKHNEELDN 1641 Query: 1583 AVPRAELDL 1591 + E +L Sbjct: 1642 QIKDLENEL 1650 Score = 192 bits (469), Expect = 5e-47 Identities = 300/1516 (19%), Positives = 672/1516 (44%), Gaps = 130/1516 (8%) Query: 140 QLGDVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXX 199 ++ D+ S +KEK ++++ K TTI +L ++E + EAK ++ Sbjct: 1045 EMTDIADNSEELKEKIDSVNEEITKRVANNTTIDELIRHLHEDLKNAEAKLQSIPHVDDN 1104 Query: 200 XXXXXXXXXXXXEDTKQQMTKMQE-----NFIAMEAEWKDEKQRLLKDIESKDVRISS-L 253 Q+ + E + + E E K ++ ++ I K ISS + Sbjct: 1105 TDSLQKSLDEVLAQISQKQRENDELNDEISRLIQEKEEKTDELNNMETIPDKREEISSEI 1164 Query: 254 EEANKLLEAAR---FEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCE-EKTE 309 E +E + +I+ E+ KLA+ELE L ++I+ E K E Sbjct: 1165 ETVKSQIEEKKKNNEKIAEENKKLAEELENLRQTLSKMETSDQPL--ENIQKEIETTKQE 1222 Query: 310 IEEKGSLEIANMTELTKKIE-LLEHLNCQIRQTNKELENKLATMGTESK----AVSSPSK 364 I EK + EL +++E + + + + ++E+EN + ++K + + Sbjct: 1223 ISEKQK----ELDELKQELEQIKDEDQSKADEISEEIENIKTQIDEKNKKNEEIAKNNEE 1278 Query: 365 KGSPLISRKSGRNTASKMKSPWSQLS---SETLNQDTDKKINKNEIAKLEMVIQSLNKDL 421 K S L + ++K +++ ET + KK K KL + L +DL Sbjct: 1279 KQSELDEKLKELQDLEEIKDETEEINQQIEETQKEIETKKQQKENNNKLNEELDKLKQDL 1338 Query: 422 VDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNT--EDVNEIA 479 E + + +D K + ++ QL + E ++ N+ E++ +I Sbjct: 1339 ---EQIENVEDNVEKLTEEIEKVKSDIDSKHQL-NNDIKEANEVVEEELNSLKEELEKIE 1394 Query: 480 KVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAA---NKNMIKVKSNHKLK 536 V+++ E+ EI V ++ IE K+ I++ N+ ++ KN ++ + K Sbjct: 1395 PVEDK-SDEIRKEI--VKIQKEIETKKATNCGISESNELLNKELNDLKNQLEEIAEEKDD 1451 Query: 537 LKQMQKTIDNFSKVSDSNKEIVRLTEELH-HLSQKVAELEEEKGNLQLHLVDYDSGRMIE 595 ++++ I+N K + KE T++ + ++ +++++L+EE Q+ +V+ D I Sbjct: 1452 SEEIKAEIENLHKSIEEKKEHNANTQQNNENMKEELSKLQEEFD--QIEVVE-DKAEEIH 1508 Query: 596 SDV--YKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEV---EDKLADISQL 650 S++ K IE +N +K + + L +EL+ LQ++YDE+ EDK ++SQ Sbjct: 1509 SEIEKLKSQIEEKNTTNNDIKEANDI------LNEELNNLQKQYDEIDVEEDKSEELSQK 1562 Query: 651 QSD--QVCSEIKSVH--LEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDI 706 +D ++ E KS + ++ + + + L ++N+++ K +E K+ I Sbjct: 1563 VTDLQKLLEEKKSQNETIKSGNENILKELQSLQNELDNIEVVSSSSEEGEKKIEKLKQMI 1622 Query: 707 MNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSK-IQTQF-GIDAKIQERDLYI 764 +K Q +E ++L+ + +EL I +++S +Q Q I KI ++ Sbjct: 1623 SDK-QKQNEETTKHNEELDNQIKDLENELNEIIPVKDKSNDLQQQIEEIKDKITDKQKKN 1681 Query: 765 ENIESELSKYKSRICRLE---ESIAVMEDRRYSLERKADQLGSYLQEKQKAYSE------ 815 E + K +L+ ++IAV+E + +++K D++ S + +K+K Y + Sbjct: 1682 EECSQLNTALKEEYDQLKSEFDNIAVIESKAEEIQQKIDEIKSEIDQKRKEYQDIKEGND 1741 Query: 816 -----YTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLS 870 YT ++ EL ++ V+ D ++ + EI + + N N+ + L Sbjct: 1742 LLEEAYTEKQKEL-EQIEVVEDKTEDLQNLIDEITEQINSRKSNNLERQVSNETFEKQLG 1800 Query: 871 DMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTL---IVQKKKEIED 927 ++Q N L + + ++ + E + + +L ++ +R++ E ++L +++ + E+ D Sbjct: 1801 QLKQELNDLPQTDDNSESLKEEIEETKKKLAMMKDEYQRMSDEDKSLTDELIRVESELND 1860 Query: 928 LEIEFNT-QIESAIR-DKKVLNEKYEKNI-EYVTQLEAQLQEYKNNIENLNMNVEELNKM 984 LE + N + E+ ++ +KK+ N+ ++ + L+AQLQ+ + E++ +E ++ Sbjct: 1861 LENQKNVLENETIVKAEKKMQNDNTIMDLRNKIDTLKAQLQQQEKPQEDIEKLKKEYQEL 1920 Query: 985 NLELIDKHVQKQQTQSPDYTEQYINEINKL-NALLKQKDEEIIALNQKINN--AQVSYMS 1041 + K Q ++ S ++E ++ + ++ + + K + +++ +L +I + AQ+ + Sbjct: 1921 KFQFDAKVSQNKEEVS--HSENELHSLKEMYDKIEKVEQQQVDSLKSQILSVKAQIDDQN 1978 Query: 1042 MVS-DYESKLAQFTTKLENMEEEMQRVSKQLLDSK--QHNEELQILVREQDDQIKELKET 1098 + + + ++ + T++ + + E+++ ++ + + +EE++ L E D++ K+ +E Sbjct: 1979 KKNEEMKKQIEKLTSEKSDAQNELEKAENKVDPDELVRLSEEIEELKLEADEKKKQNEEV 2038 Query: 1099 KLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKV--QEEEEFIQERSV 1156 + + E + K + ++ + + SD N +D + Q+ +E I Sbjct: 2039 RSSLEEELSKYKEILENLKSDNQSDIHNQIDQIKDRINEKQQENEADNQKLQEIINNHKK 2098 Query: 1157 LQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLST 1216 L E K + E+Q+ + +++ N E+ Q++IN++K KL+Q EN++ Sbjct: 2099 LLENMNKEHEEIQKQIEQ--EVDKNNKEID----QKQKEINEVKEKLQQAKKENED---D 2149 Query: 1217 VAELRSSISSA------VDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQ 1270 EL+ I + + G +L KQ + ++E + Q+ + + ++ +++K + Sbjct: 2150 KVELQRQIDNCGREIEKLQNAGDSEIDLLKQEIDKKEKERQQATEQKQHEIEMYKAKLQ- 2208 Query: 1271 LLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDE 1330 + N ++ +L+ K+ +E +N E +++++++ E+E+E Sbjct: 2209 -----HKEQENAVNAEKLHNEIENLKKKIDSQEMEYKNYNESLTKILDKLKVKLEEVEEE 2263 Query: 1331 KVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXX 1390 R +N + + Q I + EE L++++ Sbjct: 2264 N-RNEDERAEEVENLKAQIASKRKQNDAENEKLSQEINKLKEELQNLQENTEIEEMKQTV 2322 Query: 1391 XXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIED 1450 + + V Q ++K + + E T L + +DE + +R+Q IE+ Sbjct: 2323 EDLK---TQISVFGDPEQEKIKLQKEIDELTEKTEKLAEADDENDKLREQ-------IEN 2372 Query: 1451 LTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNK 1510 L K ++ I+ L E+ E Q E+ ++K E + L ++V +L+K Sbjct: 2373 LKNVKSRDVEIIDLGEEEDG---ERQQLVEELNKLKEEYEQLQNTDDINDLKQEVIDLSK 2429 Query: 1511 ALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFAS---DTKQG 1567 ++E A + QT + + E+ LN +I N+ +I+ H+ D KQ Sbjct: 2430 QIDEIKASNKDAQTKSDLLK-ELSQLNSQIENI-IQEEEDKEEIRSHIEEIKSLLDNKQS 2487 Query: 1568 RDEQLD-NTMNKELLD 1582 +++ + + + K+L D Sbjct: 2488 EEDEKELDDLKKQLED 2503 Score = 188 bits (458), Expect = 1e-45 Identities = 286/1440 (19%), Positives = 642/1440 (44%), Gaps = 138/1440 (9%) Query: 212 EDTKQQMTKMQENFIAMEA------EWKDEKQRLLKDIESKDVRISSLEEANKLL----- 260 E+ K++++K+QE F +E E E ++L IE K+ + ++EAN +L Sbjct: 1481 ENMKEELSKLQEEFDQIEVVEDKAEEIHSEIEKLKSQIEEKNTTNNDIKEANDILNEELN 1540 Query: 261 --EAARFEISLEHSKLAQELEQXXXXXXXXXXXXXX---LAKQSIEPSCEEKTEIE-EKG 314 + EI +E K ++EL Q K E +E ++ E Sbjct: 1541 NLQKQYDEIDVEEDK-SEELSQKVTDLQKLLEEKKSQNETIKSGNENILKELQSLQNELD 1599 Query: 315 SLEIANMT--ELTKKIELLEHL-------NCQIRQTNKELENKLATMGTESKAVSSPSKK 365 ++E+ + + E KKIE L+ + N + + N+EL+N++ + E + K Sbjct: 1600 NIEVVSSSSEEGEKKIEKLKQMISDKQKQNEETTKHNEELDNQIKDLENELNEIIPVKDK 1659 Query: 366 GSPLISR----KSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDL 421 + L + K K SQL++ + K + IA +E + + + + Sbjct: 1660 SNDLQQQIEEIKDKITDKQKKNEECSQLNTALKEEYDQLKSEFDNIAVIESKAEEIQQKI 1719 Query: 422 VDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDV-NEIAK 480 + + SE D G D L+ + E Q+ +E ++ TED+ N I + Sbjct: 1720 ---DEIKSEIDQKRKEYQDIKEGND-LLEEAYTEKQKELEQIEVVE--DKTEDLQNLIDE 1773 Query: 481 VQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQM 540 + EQ+ ++ ++ + EK +Q +LND + + N +K + K++ Sbjct: 1774 ITEQINSRKSNNLERQVSNETFEKQLGQLKQ--ELND-LPQTDDNSESLKEEIEETKKKL 1830 Query: 541 QKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYK 600 D + ++SD +K LT+EL + ++ +LE +K L+ + + + +++D Sbjct: 1831 AMMKDEYQRMSDEDKS---LTDELIRVESELNDLENQKNVLENETI-VKAEKKMQND--N 1884 Query: 601 KMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKL-ADISQLQSDQVCSEI 659 ++++ N +T LKA L + +K +++ L+++Y E++ + A +SQ + + SE Sbjct: 1885 TIMDLRNKIDT-LKA-QLQQQEKPQ--EDIEKLKKEYQELKFQFDAKVSQNKEEVSHSEN 1940 Query: 660 KSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMD 719 + L+E D + +++ +++LK + I D E++ +++ E D Sbjct: 1941 ELHSLKEMYDKIEKVEQQQ---VDSLKSQILSVKAQIDDQNKKNEEMKKQIEKLTSEKSD 1997 Query: 720 LTDKLEKMSAEKISELLAKINHE-EQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRI 778 ++LEK + + L +++ E E+ K++ D K ++ + ++E ELSKYK + Sbjct: 1998 AQNELEKAENKVDPDELVRLSEEIEELKLEA----DEKKKQNEEVRSSLEEELSKYKEIL 2053 Query: 779 CRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMD-----H 833 L+ D + + + DQ+ + EKQ+ + E++N L++ H Sbjct: 2054 ENLKS------DNQSDIHNQIDQIKDRINEKQQENEADNQKLQEIINNHKKLLENMNKEH 2107 Query: 834 DRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESES 893 + + ++ E++ NKE+ +K + + E + LQ + +++ + VE + D E Sbjct: 2108 EEIQKQIEQEVDKNNKEIDQKQKEINEVKEKLQQA---KKENEDDKVELQRQIDNCGREI 2164 Query: 894 TKYQ----TQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEF-NTQIESAIRDKKVLNE 948 K Q +++ L+ + + E Q QK+ EIE + + + + E+A+ +K+ NE Sbjct: 2165 EKLQNAGDSEIDLLKQEIDKKEKERQQATEQKQHEIEMYKAKLQHKEQENAVNAEKLHNE 2224 Query: 949 KYEKNIEYVTQLEAQLQEYKNN-------IENLNMNVEELNKMN---------LELIDKH 992 +N++ ++++Q EYKN ++ L + +EE+ + N +E + Sbjct: 2225 I--ENLK--KKIDSQEMEYKNYNESLTKILDKLKVKLEEVEEENRNEDERAEEVENLKAQ 2280 Query: 993 VQKQQTQSPDYTEQYINEINKLNALLK--QKDEEIIALNQKINNAQVSYMSMVSDYESKL 1050 + ++ Q+ E+ EINKL L+ Q++ EI + Q + + + +S+ D E + Sbjct: 2281 IASKRKQNDAENEKLSQEINKLKEELQNLQENTEIEEMKQTVEDLKTQ-ISVFGDPEQEK 2339 Query: 1051 AQFTTKLENMEEEMQRVSKQLLDSKQHNEELQIL--VREQDDQIKELKETK------LTF 1102 + +++ + E+ +++++ ++ + E+++ L V+ +D +I +L E + L Sbjct: 2340 IKLQKEIDELTEKTEKLAEADDENDKLREQIENLKNVKSRDVEIIDLGEEEDGERQQLVE 2399 Query: 1103 EMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSA 1162 E+N K E + +T DD N++ +K ++ Q +S L ++ + Sbjct: 2400 ELNKLKEEYEQLQNT-----DDINDLKQEVIDLSKQIDEIKASNKDA--QTKSDLLKELS 2452 Query: 1163 KLNTELQECYTKIIQLETLNTELTGH-----DVVNQEQINQLKSKLEQLNTENDNLLSTV 1217 +LN++++ IIQ E E+ H +++ +Q + + +L+ L + ++ S + Sbjct: 2453 QLNSQIEN----IIQEEEDKEEIRSHIEEIKSLLDNKQSEEDEKELDDLKKQLEDKQSLI 2508 Query: 1218 AELRSSI--SSAVDQRGFEIAELWKQHLAQREADFQKTEH--ELRVQLSAFESKYEQLLD 1273 +L+ I + +++ + + +Q ++++ E R L + +QL+ Sbjct: 2509 NKLKEDIKLTKEENEKAQKNIDDLEQEFDDLNNEYEEESQFDEERKLLETEIERLKQLIS 2568 Query: 1274 SVQSSTQEETNKIVT-MEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKV 1332 ++ +E+T+K+ + +T N L+D E+ + LQ + ++ QI ++ E ++ Sbjct: 2569 EKKTQNKEKTDKLFKEINDLTEELNSLEDDSEN-KELQSQIDELNEQINSVKEESNPQQT 2627 Query: 1333 AFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXX 1392 + E ++ K +E L ++ + ++ + Sbjct: 2628 KENLQKELDDLNNKLQQM-IEDEEENEKLKEEIDALKEELKDNKSQEENQQLKSQISELQ 2686 Query: 1393 XRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLT 1452 ++ + ++ E + L+ S+I Q +E ++R D+ ++ +++ +++I + Sbjct: 2687 EQIKQKQNEISETENSLK---SQISQLQNELKEKESERGDKSNSLYKEIDSLKEKINNQE 2743 Query: 1453 YEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKAL 1512 E +++ + L + + + + +E+E + K+ EE +E L ++ LNK L Sbjct: 2744 IENKADSSQLSDLLKDLKKKLQELTEENETIKSKISEEKEKSKSEMAKLEEEKKSLNKEL 2803 Query: 1513 EE-EVAKTNEMQTALENQEIEIVTLNDEITNLQNM-VRASSSKIQKHVSFASDTKQGRDE 1570 E + EM + E + L +I Q + K+ + +S +D + + E Sbjct: 2804 ENVNDDEDKEMLEGEVSSLKETLNLKKQINEEQKQKLSQEKEKLTEELSQLNDNEDLKKE 2863 Score = 169 bits (410), Expect = 7e-40 Identities = 318/1582 (20%), Positives = 686/1582 (43%), Gaps = 155/1582 (9%) Query: 57 AQKCLENAAL---VSKRIKEHRKATAELLGRPFVPGISESLANTLKQKEILMEKIKQYKE 113 +QK EN L +S+ I+E + T EL +P E +++ + E +K E Sbjct: 1120 SQKQRENDELNDEISRLIQEKEEKTDELNNMETIPDKREEISSEI-------ETVKSQIE 1172 Query: 114 LSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNALSVLQVKMKIMETTIL 173 K+++ I +L ++ + ++ D L +Q +++ + I Sbjct: 1173 EKKKNNEKIAEENKKLAE--------ELENLRQTLSKMETSDQPLENIQKEIETTKQEIS 1224 Query: 174 DLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWK 233 + Q++++E Q +E ++ ++ ++ +N ++E Sbjct: 1225 EKQKELDELKQELEQIKDEDQSKADEISEEIENIKTQIDEKNKKNEEIAKNNEEKQSEL- 1283 Query: 234 DEKQRLLKDIES-KDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXX 292 DEK + L+D+E KD EE N+ +E + EI + Q+ E Sbjct: 1284 DEKLKELQDLEEIKD----ETEEINQQIEETQKEIETKK----QQKENNNKLNEELDKLK 1335 Query: 293 XXLAK-QSIEPSCEEKTEIEEKGSLEIANMTELTKKI-ELLEHLNCQIRQTNKELENKLA 350 L + +++E + E+ TE EK +I + +L I E E + ++ +ELE K+ Sbjct: 1336 QDLEQIENVEDNVEKLTEEIEKVKSDIDSKHQLNNDIKEANEVVEEELNSLKEELE-KIE 1394 Query: 351 TMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQD-TDKKINKNEIAK 409 + +S + K I K N S+E LN++ D K EIA+ Sbjct: 1395 PVEDKSDEIRKEIVKIQKEIETKKATNCGISE-------SNELLNKELNDLKNQLEEIAE 1447 Query: 410 LEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVG 469 + + + ++ + I EK +++LQ E Q + V Sbjct: 1448 EKDDSEEIKAEIENLHKSIEEKKEHNANTQQNNENMKEELSKLQEEFDQ------IEVVE 1501 Query: 470 TNTEDVN-EIAKVQEQLKQE--LNDEIKDVNVKDLI-EKLKSAEEQITQLNDEIDAANKN 525 E+++ EI K++ Q++++ N++IK+ N D++ E+L + ++Q +++ E D + + Sbjct: 1502 DKAEEIHSEIEKLKSQIEEKNTTNNDIKEAN--DILNEELNNLQKQYDEIDVEEDKSEEL 1559 Query: 526 MIKVKSNHKLKLKQMQKTIDNFSKVSDSN--KEIVRLTEELHHLSQKVAELEEEKGNLQL 583 KV KL + +K+ + K + N KE+ L EL ++ +V E+G ++ Sbjct: 1560 SQKVTDLQKLL--EEKKSQNETIKSGNENILKELQSLQNELDNI--EVVSSSSEEGEKKI 1615 Query: 584 HLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLV---QELHILQQKYDEV 640 + +MI SD K+ E E I LE++ +++ + + LQQ+ +E+ Sbjct: 1616 EKLK----QMI-SDKQKQNEETTKHNEELDNQIKDLENELNEIIPVKDKSNDLQQQIEEI 1670 Query: 641 EDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLE 700 +DK+ D + + ++ CS++ + L+E+ D L + +A VIE+ E++ I ++ Sbjct: 1671 KDKITD--KQKKNEECSQLNTA-LKEEYDQLKSEFDNIA-VIES---KAEEIQQKIDEI- 1722 Query: 701 NDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQE- 759 K +I K + Y Q+ + D LE+ EK EL +I E Q ID ++ Sbjct: 1723 --KSEIDQKRKEY-QDIKEGNDLLEEAYTEKQKEL-EQIEVVEDKTEDLQNLIDEITEQI 1778 Query: 760 RDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQ 819 N+E ++S E+ + ++ L + D S +E ++ + + Sbjct: 1779 NSRKSNNLERQVSNET-----FEKQLGQLKQELNDLPQTDDNSESLKEEIEETKKKLAMM 1833 Query: 820 EDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNAL 879 +DE + D D+ + +L+ +E E +L+ + +L EN+ + + Q+ N + Sbjct: 1834 KDEYQR----MSDEDKSLTDELIRVESELNDLENQKNVL--ENETI-VKAEKKMQNDNTI 1886 Query: 880 VEKANRTDLAESE---STKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQI 936 ++ N+ D +++ K Q + L+ + + + + Q K+E+ E E ++ Sbjct: 1887 MDLRNKIDTLKAQLQQQEKPQEDIEKLKKEYQELKFQFDAKVSQNKEEVSHSENELHSLK 1946 Query: 937 ESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQ 996 E + +KV ++ + + ++AQ+ + E + +E+L + ++ + + Sbjct: 1947 EMYDKIEKVEQQQVDSLKSQILSVKAQIDDQNKKNEEMKKQIEKLTSEKSDAQNELEKAE 2006 Query: 997 QTQSPDYTEQYINEIN--KLNALLKQKDEEII--ALNQKINNAQVSYMSMVSDYES---- 1048 PD + EI KL A K+K E + +L ++++ + ++ SD +S Sbjct: 2007 NKVDPDELVRLSEEIEELKLEADEKKKQNEEVRSSLEEELSKYKEILENLKSDNQSDIHN 2066 Query: 1049 KLAQFTTKLENMEEEMQRVSKQLLD-SKQHNEELQILVREQDDQIKELKE--TKLTFEMN 1105 ++ Q ++ ++E + +++L + H + L+ + +E ++ K++++ K E++ Sbjct: 2067 QIDQIKDRINEKQQENEADNQKLQEIINNHKKLLENMNKEHEEIQKQIEQEVDKNNKEID 2126 Query: 1106 IPKTEGMIISSTIE--PMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAK 1163 + E + ++ ++ + V+ K+Q + E +L+++ K Sbjct: 2127 QKQKEINEVKEKLQQAKKENEDDKVELQRQIDNCGREIEKLQNAGD--SEIDLLKQEIDK 2184 Query: 1164 LNTELQEC-YTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRS 1222 E Q+ K ++E +L + N +L +++E L + D+ Sbjct: 2185 KEKERQQATEQKQHEIEMYKAKLQHKEQENAVNAEKLHNEIENLKKKIDSQEMEYKNYNE 2244 Query: 1223 SISSAVDQRGFEIAELWKQHL--AQREADFQKTEHEL---RVQLSAFESKYEQLLDSVQS 1277 S++ +D+ ++ E+ +++ +R + + + ++ R Q A K Q ++ ++ Sbjct: 2245 SLTKILDKLKVKLEEVEEENRNEDERAEEVENLKAQIASKRKQNDAENEKLSQEINKLKE 2304 Query: 1278 STQ--EETNKIVTMEQ-VTSLQNKLQ---DKEEHLRNLQEKYADVINQIE-ILRSEIEDE 1330 Q +E +I M+Q V L+ ++ D E+ LQ++ ++ + E + ++ E++ Sbjct: 2305 ELQNLQENTEIEEMKQTVEDLKTQISVFGDPEQEKIKLQKEIDELTEKTEKLAEADDEND 2364 Query: 1331 KVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXX 1390 K+ DL E +Q + + + EE QL+ + Sbjct: 2365 KLREQIENLKNVKSRDVEIIDLGEEEDGERQQLVEELNKLKEEYEQLQNTDD-------- 2416 Query: 1391 XXXRVNDAEAKVLELTHQL-ELKDSEIYQKTHEYTI-TLTQRNDEFENVRQQLVEYEKRI 1448 +ND + +V++L+ Q+ E+K S +T + L+Q N + EN+ Q E E + Sbjct: 2417 ----INDLKQEVIDLSKQIDEIKASNKDAQTKSDLLKELSQLNSQIENIIQ---EEEDKE 2469 Query: 1449 EDLTYEKESELAILRLKMHENANHYETMQKESE---------IERVKLIEELNVKITESV 1499 E ++ +E + + + E+ + ++K+ E E +KL +E N K +++ Sbjct: 2470 EIRSHIEEIKSLLDNKQSEEDEKELDDLKKQLEDKQSLINKLKEDIKLTKEENEKAQKNI 2529 Query: 1500 -SLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHV 1558 L ++ +LN EEE ++ +E + LE EI L I+ + + + K+ K + Sbjct: 2530 DDLEQEFDDLNNEYEEE-SQFDEERKLLET---EIERLKQLISEKKTQNKEKTDKLFKEI 2585 Query: 1559 SFASDTKQGRDEQLDNTMNKEL 1580 +D + + D++ NKEL Sbjct: 2586 ---NDLTEELNSLEDDSENKEL 2604 Score = 168 bits (409), Expect = 1e-39 Identities = 302/1491 (20%), Positives = 645/1491 (43%), Gaps = 139/1491 (9%) Query: 149 NTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQI---IEAK---NKATTXXXXXXXX 202 NTI + N + L+ +++ E D+++ E ++ +AK NK Sbjct: 1884 NTIMDLRNKIDTLKAQLQQQEKPQEDIEKLKKEYQELKFQFDAKVSQNKEEVSHSENELH 1943 Query: 203 XXXXXXXXXEDTKQQMT-KMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLE 261 E +QQ ++ ++++A+ D+ ++ + + + S +A LE Sbjct: 1944 SLKEMYDKIEKVEQQQVDSLKSQILSVKAQIDDQNKKNEEMKKQIEKLTSEKSDAQNELE 2003 Query: 262 AARFEISLEHS-KLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIAN 320 A ++ + +L++E+E+ + + S+E + EI E +L+ N Sbjct: 2004 KAENKVDPDELVRLSEEIEELKLEADEKKKQNEEV-RSSLEEELSKYKEILE--NLKSDN 2060 Query: 321 MTELTKKIELLEHLNCQIRQTNKELENKLATM-GTESKAVSSPSKKGSPL---ISRKSGR 376 +++ +I+ ++ + +Q N+ KL + K + + +K+ + I ++ + Sbjct: 2061 QSDIHNQIDQIKDRINEKQQENEADNQKLQEIINNHKKLLENMNKEHEEIQKQIEQEVDK 2120 Query: 377 NTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXX 436 N ++ +++ KK N+++ +L+ I + ++ ++K + + Sbjct: 2121 NN-KEIDQKQKEINEVKEKLQQAKKENEDDKVELQRQIDNCGRE-IEKLQNAGDSEIDLL 2178 Query: 437 XXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHV----GTNTEDV-NEIAKVQEQL-KQELN 490 K+ A Q +H+ M L H N E + NEI +++++ QE+ Sbjct: 2179 KQEIDKKEKERQQATEQKQHEIEMYKAKLQHKEQENAVNAEKLHNEIENLKKKIDSQEME 2238 Query: 491 DEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSK- 549 + + ++ +++KLK E++ + N D + + +K+ K KQ + S+ Sbjct: 2239 YKNYNESLTKILDKLKVKLEEVEEENRNEDERAEEVENLKAQIASKRKQNDAENEKLSQE 2298 Query: 550 VSDSNKEIVRLTE--ELHHLSQKVAEL----------EEEKGNLQLHLVDYD--SGRMIE 595 ++ +E+ L E E+ + Q V +L E+EK LQ + + + ++ E Sbjct: 2299 INKLKEELQNLQENTEIEEMKQTVEDLKTQISVFGDPEQEKIKLQKEIDELTEKTEKLAE 2358 Query: 596 SDVYKKMI--EMENLAETRLKAISLLE------SQKFDLVQELHILQQKYDEVEDKLADI 647 +D + ++ENL + + + +++ ++ LV+EL+ L+++Y+++++ DI Sbjct: 2359 ADDENDKLREQIENLKNVKSRDVEIIDLGEEEDGERQQLVEELNKLKEEYEQLQNT-DDI 2417 Query: 648 SQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIM 707 + L+ + + L +QID + AS K+ + LK + QL I+++ ++ED Sbjct: 2418 NDLKQEVI-------DLSKQIDEIKASNKDAQTKSDLLK-ELSQLNSQIENIIQEEED-K 2468 Query: 708 NKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKI--QERDLYIE 765 +++++I+E L D + EK + L K ++QS I + D K+ +E + + Sbjct: 2469 EEIRSHIEEIKSLLDNKQSEEDEKELDDLKKQLEDKQSLIN-KLKEDIKLTKEENEKAQK 2527 Query: 766 NIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVN 825 NI+ ++ EE E+R+ LE + ++L + EK+ E T D+L Sbjct: 2528 NIDDLEQEFDDLNNEYEEESQFDEERKL-LETEIERLKQLISEKKTQNKEKT---DKLFK 2583 Query: 826 RLAVLMDHDRVVEKQLLEIEHENKELQKK--------NQILLEEN-----QNLQISLSDM 872 + +D E LE + ENKELQ + N + E N +NLQ L D+ Sbjct: 2584 EI-----NDLTEELNSLEDDSENKELQSQIDELNEQINSVKEESNPQQTKENLQKELDDL 2638 Query: 873 QQHYNALVEKANRTDLAESESTKYQTQLRDLESN-----LKRITHEHQTLIVQKKKEIED 927 ++E + + E + +L+D +S LK E Q I QK+ EI + Sbjct: 2639 NNKLQQMIEDEEENEKLKEEIDALKEELKDNKSQEENQQLKSQISELQEQIKQKQNEISE 2698 Query: 928 LEIEFNTQIESAIRD-KKVLNEKYEKNIEYVTQLEAQLQEYKNN-IENLNMNVEELNKMN 985 E +QI + K+ +E+ +K+ ++++ ++ N IEN + +L+ + Sbjct: 2699 TENSLKSQISQLQNELKEKESERGDKSNSLYKEIDSLKEKINNQEIEN-KADSSQLSDL- 2756 Query: 986 LELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSD 1045 L+ + K +Q+ ++ + E K + + + +EE +LN+++ N + + Sbjct: 2757 LKDLKKKLQELTEENETIKSKISEEKEKSKSEMAKLEEEKKSLNKELENVNDDEDKEMLE 2816 Query: 1046 YESKLAQFTTKLENM--EEEMQRVSKQL------LDSKQHNEELQILVREQDDQIKELK- 1096 E + T L+ EE+ Q++S++ L NE+L+ + ++ +++++LK Sbjct: 2817 GEVSSLKETLNLKKQINEEQKQKLSQEKEKLTEELSQLNDNEDLKKEIEQKKEELEKLKN 2876 Query: 1097 ETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSV 1156 ++ L E+ K + S P L E+ Q+ + Sbjct: 2877 DSSLLQELQDLKKQIEEKSEKQNPELLKQIEDLKKEISEKESENDLITGEKNTVEQQYNK 2936 Query: 1157 LQEQSAKLNTELQECYTKIIQLETLNTELTGHD----VVNQEQINQLKSKLEQLNTENDN 1212 L EQ L + ++ K+ L EL+ + + N+++ ++K +E++ + + Sbjct: 2937 LVEQRKYLESTMEAAKKKVSDLRQQCDELSMKNNQFRIDNEKEFQEIKKSIEEIKGQREQ 2996 Query: 1213 LLSTVAELRSSISSAVDQRGFEIAELWKQHL--AQREADFQKTEHELRVQLSAFESKYEQ 1270 L E + +R E L +Q L AQ++ D +K ++E +++ + + K Sbjct: 2997 LAKKHNEDK--------RRAREYNTLARQKLTDAQQKLDAEKAKNENLLKMMSEQEKTVS 3048 Query: 1271 LLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDE 1330 L+ +S E+ NK + +Q+TS + QDK E LR +E +++ L E+ + Sbjct: 3049 NLEK-ESEDLEQKNKELE-QQMTSTGDFSQDKIEELRKKKE-------ELQKLNDELSQK 3099 Query: 1331 KVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXX 1390 + L E +S K E + +E+ +++K Sbjct: 3100 Q----KQNIEQSNSLQNEKVTLSNEIESLKSSTEA----MEKESTEMEKKLEEDKGIISE 3151 Query: 1391 XXXRVNDAEAKVLEL---THQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKR 1447 D E K E + +L+ + +E+ +K + T T ND+ ++ + E+R Sbjct: 3152 KSKEKEDLEKKSKEQQEKSDKLKQEVAELQEKAKKITTENTDLNDKITDLEISISNAERR 3211 Query: 1448 IEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITE-SVSLNKQVA 1506 +DL E E A L+ E +K+ E+ +K + N++ E S+SL +Q Sbjct: 3212 KKDLEEEIEKSSA-KSLQEKEKELEEIAEKKKKEVREMKKQHKQNIRSLESSISLLEQDI 3270 Query: 1507 ELNKALEE-EVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQK 1556 K+LEE + + Q L+ + ++ L + L++++ S+++K Sbjct: 3271 ---KSLEEIQNSSKKSEQEGLQLLDEKVADLKIKKFELEDIIADRDSELKK 3318 Score = 158 bits (384), Expect = 1e-36 Identities = 333/1645 (20%), Positives = 695/1645 (42%), Gaps = 189/1645 (11%) Query: 53 KFERAQKCLENAALVSKRIKEHRKATAELLGRPFVPGISESLANTLKQKEILMEKIKQYK 112 + + Q L+N +VS +E K +L + + + T K E L +IK + Sbjct: 1590 ELQSLQNELDNIEVVSSSSEEGEKKIEKL--KQMISDKQKQNEETTKHNEELDNQIKDLE 1647 Query: 113 -ELSK----RSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNALSVLQVKMKI 167 EL++ + + ++ + + + L+ +KE+ + L + + Sbjct: 1648 NELNEIIPVKDKSNDLQQQIEEIKDKITDKQKKNEECSQLNTALKEEYDQLKSEFDNIAV 1707 Query: 168 METTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIA 227 +E+ ++Q+KI+E I+ K K E+ + K E Sbjct: 1708 IESKAEEIQQKIDEIKSEIDQKRKE--------YQDIKEGNDLLEEAYTEKQKELEQIEV 1759 Query: 228 MEAEWKDEKQ---RLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXX 284 +E + +D + + + I S+ + +N+ E ++ E + L Q + Sbjct: 1760 VEDKTEDLQNLIDEITEQINSRKSNNLERQVSNETFEKQLGQLKQELNDLPQTDDNSESL 1819 Query: 285 XXXXXXXXXXLAKQSIE---PSCEEKTEIEEKGSLEIANMTELTKKIELLEH-------L 334 LA E S E+K+ +E +E + + +L + +LE+ Sbjct: 1820 KEEIEETKKKLAMMKDEYQRMSDEDKSLTDELIRVE-SELNDLENQKNVLENETIVKAEK 1878 Query: 335 NCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETL 394 Q T +L NK+ T+ + + P + L +K + + + SQ E Sbjct: 1879 KMQNDNTIMDLRNKIDTLKAQLQQQEKPQEDIEKL--KKEYQELKFQFDAKVSQNKEEVS 1936 Query: 395 NQDTDKKINKNEIAKLEMV----IQSLNKDLVDKEYVISE--KDTXXXXXXXXXXGKDTL 448 + + + K K+E V + SL ++ + I + K + Sbjct: 1937 HSENELHSLKEMYDKIEKVEQQQVDSLKSQILSVKAQIDDQNKKNEEMKKQIEKLTSEKS 1996 Query: 449 IAQLQLEHQQHMEGPS-LIHVGTNTEDV----NEIAKVQEQLKQELNDEIKDVNVKDLIE 503 AQ +LE ++ P L+ + E++ +E K E+++ L +E+ K+++E Sbjct: 1997 DAQNELEKAENKVDPDELVRLSEEIEELKLEADEKKKQNEEVRSSLEEELS--KYKEILE 2054 Query: 504 KLKSAEE-----QITQLNDEI-------DAANKNMIKVKSNHKLKLKQMQKTIDNFSK-- 549 LKS + QI Q+ D I +A N+ + ++ +NHK L+ M K + K Sbjct: 2055 NLKSDNQSDIHNQIDQIKDRINEKQQENEADNQKLQEIINNHKKLLENMNKEHEEIQKQI 2114 Query: 550 ---VSDSNKEIVRLTEELHHLSQKV--AELEEEKGNLQLHLVDYDSGRMIES-------- 596 V +NKEI + +E++ + +K+ A+ E E ++L + GR IE Sbjct: 2115 EQEVDKNNKEIDQKQKEINEVKEKLQQAKKENEDDKVELQRQIDNCGREIEKLQNAGDSE 2174 Query: 597 ------DVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQK-YDEVED--KLADI 647 ++ KK E + E + I + +++ QE + +K ++E+E+ K D Sbjct: 2175 IDLLKQEIDKKEKERQQATEQKQHEIEMYKAKLQHKEQENAVNAEKLHNEIENLKKKIDS 2234 Query: 648 SQLQ----SDQVCSEIKSVHLE-EQIDALSASKKELALVIENLKLDKEQLYGTIKDLEND 702 +++ ++ + + + ++ E+++ + ++ E A +ENLK D EN+ Sbjct: 2235 QEMEYKNYNESLTKILDKLKVKLEEVEEENRNEDERAEEVENLKAQIASKRKQ-NDAENE 2293 Query: 703 K-EDIMNKLQNYIQENMDLTDKLE-KMSAEKISELLAKINHEEQSKIQTQFGIDAKIQER 760 K +NKL+ +Q + T+ E K + E + ++ EQ KI+ Q ID ++ E+ Sbjct: 2294 KLSQEINKLKEELQNLQENTEIEEMKQTVEDLKTQISVFGDPEQEKIKLQKEID-ELTEK 2352 Query: 761 DLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKAD-QLGSYLQEKQKAYSEYT-I 818 + + E K + +I L+ ++ + L + D + ++E K EY + Sbjct: 2353 TEKLAEADDENDKLREQIENLK-NVKSRDVEIIDLGEEEDGERQQLVEELNKLKEEYEQL 2411 Query: 819 QEDELVNRLAV-LMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYN 877 Q + +N L ++D + KQ+ EI+ NK+ Q K+ +L E +Q N Sbjct: 2412 QNTDDINDLKQEVID----LSKQIDEIKASNKDAQTKSDLLKELSQ------------LN 2455 Query: 878 ALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIE 937 + +E + + + E + +++ L N + + E + + KK++ED + N +++ Sbjct: 2456 SQIENIIQEEEDKEEIRSHIEEIKSLLDNKQ--SEEDEKELDDLKKQLEDKQSLIN-KLK 2512 Query: 938 SAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEE--LNKMNLELIDKHVQK 995 I+ K NEK +KNI+ LE + + N E + EE L + +E + + + + Sbjct: 2513 EDIKLTKEENEKAQKNID---DLEQEFDDLNNEYEEESQFDEERKLLETEIERLKQLISE 2569 Query: 996 QQTQSPDYTEQYINEIN----KLNALL-----KQKDEEIIALNQKIN------NAQVSYM 1040 ++TQ+ + T++ EIN +LN+L K+ +I LN++IN N Q + Sbjct: 2570 KKTQNKEKTDKLFKEINDLTEELNSLEDDSENKELQSQIDELNEQINSVKEESNPQQTKE 2629 Query: 1041 SM---VSDYESKLAQFTT---KLENMEEEMQRVSKQLLDSK--QHNEELQILVREQDDQI 1092 ++ + D +KL Q + E ++EE+ + ++L D+K + N++L+ + E +QI Sbjct: 2630 NLQKELDDLNNKLQQMIEDEEENEKLKEEIDALKEELKDNKSQEENQQLKSQISELQEQI 2689 Query: 1093 K----ELKETKLTFEMNIPKTEGMI-------------ISSTIEPMSDDANNVDXXXXXX 1135 K E+ ET+ + + I + + + + I+ + + NN + Sbjct: 2690 KQKQNEISETENSLKSQISQLQNELKEKESERGDKSNSLYKEIDSLKEKINNQEIENKAD 2749 Query: 1136 XXXXXXLKVQEEEEFIQERSVLQEQ-SAKLNTELQECYTKIIQLE----TLNTELTGHDV 1190 L +++ ++ +QE + E +K++ E ++ +++ +LE +LN EL +V Sbjct: 2750 SSQLSDL-LKDLKKKLQELTEENETIKSKISEEKEKSKSEMAKLEEEKKSLNKEL--ENV 2806 Query: 1191 VNQEQINQLKSKLEQLNTENDNLLSTV-AELRSSISSAVDQRGFEIAELWKQHLAQREAD 1249 + E L+ ++ L E NL + E + +S ++ E+++L ++E + Sbjct: 2807 NDDEDKEMLEGEVSSLK-ETLNLKKQINEEQKQKLSQEKEKLTEELSQLNDNEDLKKEIE 2865 Query: 1250 FQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEH---- 1305 +K E E S+ + + L ++ ++++ ++ ++Q+ L+ ++ +KE Sbjct: 2866 QKKEELEKLKNDSSLLQELQDLKKQIEEKSEKQNPEL--LKQIEDLKKEISEKESENDLI 2923 Query: 1306 ---LRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQM 1362 ++++Y ++ Q + L S +E K R +N+ Q Sbjct: 2924 TGEKNTVEQQYNKLVEQRKYLESTMEAAKKKVSDLRQQCDELSMKNN-QFRIDNEKEFQE 2982 Query: 1363 QEQSILNINEENAQLKKS----SXXXXXXXXXXXXRVNDAEAKV--LELTHQLELKDSEI 1416 ++SI I + QL K ++ DA+ K+ + ++ LK Sbjct: 2983 IKKSIEEIKGQREQLAKKHNEDKRRAREYNTLARQKLTDAQQKLDAEKAKNENLLKMMSE 3042 Query: 1417 YQKT----HEYTITLTQRNDEFENVRQQLVEYEK-RIEDLTYEKESELAILRLKMHENAN 1471 +KT + + L Q+N E E ++ + +IE+L +KE EL L ++ + Sbjct: 3043 QEKTVSNLEKESEDLEQKNKELEQQMTSTGDFSQDKIEELRKKKE-ELQKLNDELSQKQK 3101 Query: 1472 HYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEI 1531 + E+V L E+ + + ++ K+ E+ K LEE+ +E E+ E Sbjct: 3102 QNIEQSNSLQNEKVTLSNEIESLKSSTEAMEKESTEMEKKLEEDKGIISEKSKEKEDLEK 3161 Query: 1532 EIVTLNDEITNLQNMVRASSSKIQK 1556 + ++ L+ V K +K Sbjct: 3162 KSKEQQEKSDKLKQEVAELQEKAKK 3186 Score = 153 bits (371), Expect = 4e-35 Identities = 249/1290 (19%), Positives = 534/1290 (41%), Gaps = 95/1290 (7%) Query: 321 MTELTKKIELLEHLNCQIRQTNKELENKLATMGTE---SKAVSSPSKKGSPLISRKSGRN 377 + E ++++ LEH N + NKEL+ K + E + ++ I + Sbjct: 65 LKEQSQRMIELEHQNESLEYENKELKAKTISFVGEFPNTSGINQADDSNETEIKIRKLMR 124 Query: 378 TASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXX 437 T +K + + L E N++ + + KL D +I + Sbjct: 125 TINKQRRDIADL--EQKNKELQEAATNGPLMKLPASEGGPGLDETKSALLIKQ---LYRE 179 Query: 438 XXXXXXGKDTLIAQLQLEHQQHMEGPSLIHV-GTNTEDVNEIAKVQEQLKQELNDEIKDV 496 D+L QLQ + ++ + + + +++ I + + +L EL Sbjct: 180 NARSKVQMDSLRKQLQDKDEEIKNLKAATDLSNSRISELSGIIEGESKL-SELKTPPSSP 238 Query: 497 NVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKE 556 + ++ I++ + ++ QL D++D + N + K + + ++ +++ D E Sbjct: 239 SYRNFIDRGNYKDRRMKQLKDQLDQTETEI----ENEEGKTENLNYSL---NEMIDLVAE 291 Query: 557 IVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAI 616 R +EL + K +EEK Q+ +ES+ K E+++L E I Sbjct: 292 RRRALQELRNSQGK----DEEKLKKQI--------AKVESEKTKIEDEIKHLQEDEEPQI 339 Query: 617 SLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEI-KSVHLEEQIDALSASK 675 L+ + + + I ++K E+ + D Q + + + I + L + + Sbjct: 340 KKLKDRLDETTTKTQIAEKKLGEMRKTIEDSRQKLAQRRQNLIERRKELTNDAENTNTEL 399 Query: 676 KELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYI-QENMDLTDKLEKMSAEKISE 734 + + I+ + + +L G + +++D + LQ + Q+ DL D K + EK S Sbjct: 400 QSINNQIQEIDSEFNKLNGLVNKVQSDHSKKKSALQEQLAQKQKDLNDLKRKQAEEKASR 459 Query: 735 --LLAKINHE------EQSKIQTQFGIDAK--IQERDLYIENIESELSKYKSRIC-RLEE 783 +AKIN + E + + +D K I + ++ +ES ++K + + + + Sbjct: 460 EAEIAKINDQLQKTMKEYNDLNQPQNVDLKNEIDQATKDLKELESRVNKKREELFGKNNQ 519 Query: 784 SIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLE 843 +A + L+ K D++ QE Q A E+ +++EL + + D ++ +L Sbjct: 520 RVAELNKLNEQLKSKMDEMVKADQELQSAKDEHEAKKNELKAEIESVSDEISKLKDELEV 579 Query: 844 I-EHENKELQKKNQILLEENQNLQISLSDMQQHYNALV---------EKANRTDLAESES 893 I + E +L+ + LL+E + L+ N+ + EKAN+ ++E E Sbjct: 580 IPDFEVDDLKDQLNELLKEKEELEKEKIKNNDELNSSIIMLKDEIQKEKANKDKISE-EK 638 Query: 894 TKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKN 953 K +L D +S L+ E +L + + + D E ++S + D K+L Sbjct: 639 NKRDKELNDEKSKLQ---DELDSLQLDEIENENDQLFEEVEDLKSKVDDAKILYNDMVDK 695 Query: 954 IEYVTQLEAQLQEYKNNIENLNM-NVEELNKMNLELID-KHVQKQQTQSPDYTEQYINEI 1011 I+ + Q +++++ ++E N +E+ K++ E+ + K Q D T + ++ Sbjct: 696 IDDLKQQRSKVEQKYKDLEKQNKEKSDEIEKVSKEISELKEKLDNLNQFKDNTPELHQKV 755 Query: 1012 NKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQL 1071 + +N + +K +E + +++N + ++ E ++ + E ++E++ + +Q+ Sbjct: 756 DAMNEQIVKKSQENEKIQEEMNKLNEELQHLENEME-EIEVVNDERETIQEKIDNIKQQI 814 Query: 1072 LDSKQHNEELQ----ILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANN 1127 + K+ NEE+Q +L+ ++D KEL ++ I + + I I+ + D N Sbjct: 815 EEKKKSNEEIQDIMNLLIEAENDAQKELD------DIEIVEAQSEEIRQRIQTLQD--NL 866 Query: 1128 VDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTG 1187 D K+Q+E + +Q +Q+ +N + + K+ +++ E Sbjct: 867 QDRKKLNNELTEQNNKLQKELKDLQNE---LDQTELVNDDSESLNKKLDEIKEQINERKS 923 Query: 1188 HDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQRE 1247 + N EQ +L ++E+ E D + + + + + + + +I E K + Q + Sbjct: 924 QNENNTEQNEKLIEEIEKFAKELDE-IEIIEDKSDKLQAQISELQKQIDEKQKNN-EQTD 981 Query: 1248 ADFQKTEHELRVQLSAFESKYEQLLDS-VQSSTQEETNKIVTMEQVTSLQNKLQDKEEHL 1306 EHEL++ +S +S S E NK +E++ NKL+ + + Sbjct: 982 KSNNDLEHELQITKQKLDSMSSVKNNSDYLKSEIENVNK--EIEKIRDTNNKLKQELQDK 1039 Query: 1307 RNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQS 1366 E+ D+ + E L+ +I+ E+ + + QS Sbjct: 1040 NKELEEMTDIADNSEELKEKIDSVNEEITKRVANNTTIDELIRH--LHEDLKNAEAKLQS 1097 Query: 1367 ILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTIT 1426 I ++++ L+KS ++ ++ L + E K E+ Sbjct: 1098 IPHVDDNTDSLQKSLDEVLAQISQKQRENDELNDEISRLIQEKEEKTDEL-NNMETIPDK 1156 Query: 1427 LTQRNDEFENVRQQLVEYEKRIEDLTYEKE---SELAILR---LKMHENANHYETMQKES 1480 + + E E V+ Q+ E +K E + E + EL LR KM + E +QK Sbjct: 1157 REEISSEIETVKSQIEEKKKNNEKIAEENKKLAEELENLRQTLSKMETSDQPLENIQK-- 1214 Query: 1481 EIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEI 1540 EIE K +E++ K E L++ EL + +E+ +K +E+ +EN + +I N + Sbjct: 1215 EIETTK--QEISEKQKE---LDELKQELEQIKDEDQSKADEISEEIENIKTQIDEKNKKN 1269 Query: 1541 TNLQNMVRASSSKIQKHVSFASDTKQGRDE 1570 + S++ + + D ++ +DE Sbjct: 1270 EEIAKNNEEKQSELDEKLKELQDLEEIKDE 1299 Score = 147 bits (355), Expect = 3e-33 Identities = 242/1223 (19%), Positives = 522/1223 (42%), Gaps = 116/1223 (9%) Query: 174 DLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWK 233 ++ +K E+ Q E K E ++ +++ + E E+K Sbjct: 2181 EIDKKEKERQQATEQKQHEIEMYKAKLQHKEQENAVNAEKLHNEIENLKKKIDSQEMEYK 2240 Query: 234 DEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXX 293 + + L K ++ V++ +EE N+ + E+ +++A + +Q Sbjct: 2241 NYNESLTKILDKLKVKLEEVEEENRNEDERAEEVENLKAQIASKRKQNDAENEKLSQEIN 2300 Query: 294 XLAKQSIEPSCEEKTEIEEKGSLEIANMTELT-------KKIELLEHLNCQIRQTNKELE 346 L K+ ++ + +E TEIEE T+++ +KI+L + ++ +T K E Sbjct: 2301 KL-KEELQ-NLQENTEIEEMKQTVEDLKTQISVFGDPEQEKIKLQKEIDELTEKTEKLAE 2358 Query: 347 -----NKLATMGTESKAVSSPSKKGSPLISRKSGRNTA-----SKMKSPWSQLSSETLNQ 396 +KL K V S + L + G +K+K + QL + + Sbjct: 2359 ADDENDKLREQIENLKNVKSRDVEIIDLGEEEDGERQQLVEELNKLKEEYEQL--QNTDD 2416 Query: 397 DTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEH 456 D K +++K I++ NKD K ++ E ++ + E Sbjct: 2417 INDLKQEVIDLSKQIDEIKASNKDAQTKSDLLKELSQLNSQIENIIQEEED-----KEEI 2471 Query: 457 QQHMEG-PSLIHVGTNTEDVNEIAKVQEQL--KQELNDEIKDVNVKDLIEKLKSAEEQIT 513 + H+E SL+ + ED E+ +++QL KQ L +++K+ ++K E+ + A++ I Sbjct: 2472 RSHIEEIKSLLDNKQSEEDEKELDDLKKQLEDKQSLINKLKE-DIKLTKEENEKAQKNID 2530 Query: 514 QLNDEIDAANKNM---IKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIV-RLTEELHHLSQ 569 L E D N + KL ++++ S+ NKE +L +E++ L++ Sbjct: 2531 DLEQEFDDLNNEYEEESQFDEERKLLETEIERLKQLISEKKTQNKEKTDKLFKEINDLTE 2590 Query: 570 KVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQ- 628 ++ LE++ N +L + I S K+ + E K + L ++ +++ Sbjct: 2591 ELNSLEDDSENKELQSQIDELNEQINS--VKEESNPQQTKENLQKELDDLNNKLQQMIED 2648 Query: 629 --ELHILQQKYDEVEDKLADI-SQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENL 685 E L+++ D ++++L D SQ ++ Q+ S+I L+EQI + E++ +L Sbjct: 2649 EEENEKLKEEIDALKEELKDNKSQEENQQLKSQISE--LQEQI---KQKQNEISETENSL 2703 Query: 686 KLDKEQLYGTIKDLENDKEDIMNKLQNYI---QENMDLTDKLEKMSAEKISELLAKINH- 741 K QL +K+ E+++ D N L I +E ++ + K + ++S+LL + Sbjct: 2704 KSQISQLQNELKEKESERGDKSNSLYKEIDSLKEKINNQEIENKADSSQLSDLLKDLKKK 2763 Query: 742 -----EEQSKIQTQFGID--------AKIQER----DLYIENIESELSK--YKSRICRLE 782 EE I+++ + AK++E + +EN+ + K + + L+ Sbjct: 2764 LQELTEENETIKSKISEEKEKSKSEMAKLEEEKKSLNKELENVNDDEDKEMLEGEVSSLK 2823 Query: 783 ESI----AVMEDRRYSLERKADQLG---SYLQEKQKAYSEYTIQEDEL--VNRLAVLMDH 833 E++ + E+++ L ++ ++L S L + + E +++EL + + L+ Sbjct: 2824 ETLNLKKQINEEQKQKLSQEKEKLTEELSQLNDNEDLKKEIEQKKEELEKLKNDSSLLQE 2883 Query: 834 DRVVEKQLLE-IEHENKELQK-----KNQILLEENQNLQIS--LSDMQQHYNALVEKANR 885 + ++KQ+ E E +N EL K K +I +E++N I+ + ++Q YN LVE+ Sbjct: 2884 LQDLKKQIEEKSEKQNPELLKQIEDLKKEISEKESENDLITGEKNTVEQQYNKLVEQRKY 2943 Query: 886 TDLAESESTKYQTQLRD------LESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESA 939 + + K + LR +++N RI +E + + KK IE+++ + + Sbjct: 2944 LESTMEAAKKKVSDLRQQCDELSMKNNQFRIDNEKE--FQEIKKSIEEIKGQREQLAKKH 3001 Query: 940 IRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKM---------NLELID 990 DK+ E + +T + +L K ENL + E K +LE + Sbjct: 3002 NEDKRRAREYNTLARQKLTDAQQKLDAEKAKNENLLKMMSEQEKTVSNLEKESEDLEQKN 3061 Query: 991 KHVQKQQTQSPDYTEQYINEINK-------LNALLKQKDEEIIALNQKINNAQVSYMSMV 1043 K +++Q T + D+++ I E+ K LN L QK ++ I + + N +V+ + + Sbjct: 3062 KELEQQMTSTGDFSQDKIEELRKKKEELQKLNDELSQKQKQNIEQSNSLQNEKVTLSNEI 3121 Query: 1044 SDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFE 1103 +S + ME++++ + + + E+L+ +EQ ++ +LK+ + Sbjct: 3122 ESLKSSTEAMEKESTEMEKKLEEDKGIISEKSKEKEDLEKKSKEQQEKSDKLKQEVAELQ 3181 Query: 1104 MNIPK--TEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQS 1161 K TE ++ I + +N + + +E +E + E+ Sbjct: 3182 EKAKKITTENTDLNDKITDLEISISNAERRKKDLEEEIEKSSAKSLQEKEKELEEIAEKK 3241 Query: 1162 AKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTE-NDNLLSTVAEL 1220 K E+++ + + I+ + L D+ + E+I K EQ + D ++ + Sbjct: 3242 KKEVREMKKQHKQNIRSLESSISLLEQDIKSLEEIQNSSKKSEQEGLQLLDEKVADLKIK 3301 Query: 1221 RSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQ 1280 + + + R E+ + W++ L ++ + + ++R K +Q+ + ++ + Sbjct: 3302 KFELEDIIADRDSELKK-WEKELLEKNKELSEVNRQIRALKG---DKIDQIKEDIKDIDE 3357 Query: 1281 EETNKIVTMEQVTSLQNKLQDKE 1303 E +K + T N +++E Sbjct: 3358 EIESKKKKLNLNTVEDNDEEEEE 3380 Score = 120 bits (289), Expect = 3e-25 Identities = 181/928 (19%), Positives = 421/928 (45%), Gaps = 70/928 (7%) Query: 217 QMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEE--ANKLLEAARFEISLEHSKL 274 ++ ++++ + + K++ +L K+I ++SLE+ NK L++ E++ + + + Sbjct: 2559 EIERLKQLISEKKTQNKEKTDKLFKEINDLTEELNSLEDDSENKELQSQIDELNEQINSV 2618 Query: 275 AQEL--EQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLE 332 +E +Q +Q IE E + EE +L+ + K E + Sbjct: 2619 KEESNPQQTKENLQKELDDLNNKLQQMIEDEEENEKLKEEIDALK--EELKDNKSQEENQ 2676 Query: 333 HLNCQIRQTNKELENKLATMG-TESKAVSSPSKKGSPLISRKSGRNTASK-MKSPWSQLS 390 L QI + ++++ K + TE+ S S+ + L ++S R S + L Sbjct: 2677 QLKSQISELQEQIKQKQNEISETENSLKSQISQLQNELKEKESERGDKSNSLYKEIDSLK 2736 Query: 391 SETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIA 450 + NQ+ + K + ++++ L ++ L K L + + E +T + +A Sbjct: 2737 EKINNQEIENKADSSQLSDL---LKDLKKKLQE---LTEENETIKSKISEEKEKSKSEMA 2790 Query: 451 QLQLEHQQHMEGPSLIHVGTNTEDVN-EIAKVQE--QLKQELNDEIKDVNVKDLIEKLKS 507 +L+ E + + ++ + E + E++ ++E LK+++N+E K + L ++ + Sbjct: 2791 KLEEEKKSLNKELENVNDDEDKEMLEGEVSSLKETLNLKKQINEEQK----QKLSQEKEK 2846 Query: 508 AEEQITQLNDEIDAANKNMIKVKSNHKLKLKQ--MQKTIDNFSKVSD-SNKEIVRLTEEL 564 E+++QLND D + K + KLK +Q+ D ++ + S K+ L +++ Sbjct: 2847 LTEELSQLNDNEDLKKEIEQKKEELEKLKNDSSLLQELQDLKKQIEEKSEKQNPELLKQI 2906 Query: 565 HHLSQKVAELEEEKGNL--QLHLVDYDSGRMIESDVY-KKMIEM--ENLAETRLKA--IS 617 L ++++E E E + + + V+ +++E Y + +E + +++ R + +S Sbjct: 2907 EDLKKEISEKESENDLITGEKNTVEQQYNKLVEQRKYLESTMEAAKKKVSDLRQQCDELS 2966 Query: 618 LLESQ-KFDLVQELHILQQKYDEVEDKLADISQLQSDQV--CSEIKSVHLEEQIDALSAS 674 + +Q + D +E +++ +E++ + +++ ++ E ++ ++ DA Sbjct: 2967 MKNNQFRIDNEKEFQEIKKSIEEIKGQREQLAKKHNEDKRRAREYNTLARQKLTDAQQKL 3026 Query: 675 KKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISE 734 E A LK+ EQ T+ +LE + ED+ K + Q+ D S +KI E Sbjct: 3027 DAEKAKNENLLKMMSEQ-EKTVSNLEKESEDLEQKNKELEQQMTSTGD----FSQDKIEE 3081 Query: 735 LLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYS 794 L K EE K+ + K +NIE S ++ L I ++ + Sbjct: 3082 LRKK--KEELQKLNDELSQKQK--------QNIEQSNSLQNEKVT-LSNEIESLKSSTEA 3130 Query: 795 LERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKK 854 +E+++ ++ L+E + SE + ++++L + + +++++ E++ + K++ + Sbjct: 3131 MEKESTEMEKKLEEDKGIISEKSKEKEDLEKKSKEQQEKSDKLKQEVAELQEKAKKITTE 3190 Query: 855 NQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEH 914 N L ++ +L+IS+S+ ++ L E ++ +S + Q + ++LE ++ E Sbjct: 3191 NTDLNDKITDLEISISNAERRKKDLEE-----EIEKSSAKSLQEKEKELEEIAEKKKKEV 3245 Query: 915 QTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKN----IEYVTQLEAQLQEYKNN 970 + + Q K+ I LE + +E I+ + + +K+ ++ + + A L+ K Sbjct: 3246 REMKKQHKQNIRSLESSISL-LEQDIKSLEEIQNSSKKSEQEGLQLLDEKVADLKIKKFE 3304 Query: 971 IENLNMNVE-ELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALN 1029 +E++ + + EL K EL++K+ + + + ++I+++ +K DEEI + Sbjct: 3305 LEDIIADRDSELKKWEKELLEKNKELSEVNRQIRALKG-DKIDQIKEDIKDIDEEIESKK 3363 Query: 1030 QKINNAQVSYMSMVSDYESKLAQFTTKLENMEEE--------MQRVSKQLLDSKQHNEEL 1081 +K+N V + SK FT + E+ + + KQ ++K+ N + Sbjct: 3364 KKLNLNTVEDNDEEEEESSKPKIFTPTISKPSEQEDNKPKIFVPTIPKQNEENKEENNKP 3423 Query: 1082 QILVREQDDQIKELKETKLTFEMNIPKT 1109 ++ V Q +E K+ + + +P T Sbjct: 3424 KVFVPVVPKQTEEQKKEEEKPKFFVPTT 3451 Score = 102 bits (245), Expect = 7e-20 Identities = 177/890 (19%), Positives = 365/890 (41%), Gaps = 82/890 (9%) Query: 722 DKLEKMS-AEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICR 780 D ++ +S +K+ E+ ++ + I + ++ + +EL + R+ Sbjct: 15 DSIKNISNTKKLQEICLQLYKNRHNLIDVNKQLAQQLARAQQRSQEAYNELKEQSQRMIE 74 Query: 781 LEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQ 840 LE +E L+ K E E+ ++ LM + Sbjct: 75 LEHQNESLEYENKELKAKTISFVGEFPNTSGINQADDSNETEI--KIRKLMRTINKQRRD 132 Query: 841 LLEIEHENKELQKKNQILLEENQNLQISLSD----MQQHYNALVEKA----NRTDLAESE 892 + ++E +NKELQ+ +++ S+ + + +AL+ K N + + Sbjct: 133 IADLEQKNKELQEA----ATNGPLMKLPASEGGPGLDETKSALLIKQLYRENARSKVQMD 188 Query: 893 STKYQTQLRDLE-SNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYE 951 S + Q Q +D E NLK T + I + IE + + + ++ Sbjct: 189 SLRKQLQDKDEEIKNLKAATDLSNSRISELSGIIEGESKLSELKTPPSSPSYRNFIDRGN 248 Query: 952 KNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEI 1011 + QL+ QL + + IEN E LN E+ID ++++ Q +E Sbjct: 249 YKDRRMKQLKDQLDQTETEIENEEGKTENLNYSLNEMIDLVAERRRALQELRNSQGKDE- 307 Query: 1012 NKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQL 1071 KL + + + E + +I + Q + + +L + TTK + E+++ + K + Sbjct: 308 EKLKKQIAKVESEKTKIEDEIKHLQEDEEPQIKKLKDRLDETTTKTQIAEKKLGEMRKTI 367 Query: 1072 LDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXX 1131 DS+Q L + + + I+ KE LT + TE I++ I+ + + N ++ Sbjct: 368 EDSRQK------LAQRRQNLIERRKE--LTNDAENTNTELQSINNQIQEIDSEFNKLNGL 419 Query: 1132 XXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQL-ETLNTELTGHDV 1190 K +E+ Q++ L + K E +I ++ + L + ++ Sbjct: 420 VNKVQSDHSKKKSALQEQLAQKQKDLNDLKRKQAEEKASREAEIAKINDQLQKTMKEYND 479 Query: 1191 VNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADF 1250 +NQ Q LK++++Q + L S V + R + +QR E+ +L +Q L + + Sbjct: 480 LNQPQNVDLKNEIDQATKDLKELESRVNKKREELFGKNNQRVAELNKLNEQ-LKSKMDEM 538 Query: 1251 QKTEHELRVQLSAFESKYEQLLDSVQSSTQEETN-----KIVTMEQVTSLQNKLQD---K 1302 K + EL+ E+K +L ++S + E + +++ +V L+++L + + Sbjct: 539 VKADQELQSAKDEHEAKKNELKAEIESVSDEISKLKDELEVIPDFEVDDLKDQLNELLKE 598 Query: 1303 EEHLRNLQEKYADVINQ-IEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQ 1361 +E L + K D +N I +L+ EI+ EK A D +++ Q + Sbjct: 599 KEELEKEKIKNNDELNSSIIMLKDEIQKEK-ANKDKISEEKNKRDKELNDEKSKLQD--E 655 Query: 1362 MQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTH 1421 + + I EN QL + ND K+ +L Q S++ QK Sbjct: 656 LDSLQLDEIENENDQLFEEVEDLKSKVDDAKILYNDMVDKIDDLKQQR----SKVEQKYK 711 Query: 1422 EYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESE 1481 + +++DE E V +++ E +++++ N N + K++ Sbjct: 712 DLEKQNKEKSDEIEKVSKEISELKEKLD-------------------NLNQF----KDNT 748 Query: 1482 IERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEIT 1541 E + ++ +N +I + ++ N+ ++EE+ K NE LEN+ EI +NDE Sbjct: 749 PELHQKVDAMNEQIVKK-------SQENEKIQEEMNKLNEELQHLENEMEEIEVVNDERE 801 Query: 1542 NLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDL 1591 +Q + +I++ K+ +E++ + MN L++A A+ +L Sbjct: 802 TIQEKIDNIKQQIEE--------KKKSNEEIQDIMNL-LIEAENDAQKEL 842 Score = 93.9 bits (223), Expect = 3e-17 Identities = 191/933 (20%), Positives = 379/933 (40%), Gaps = 77/933 (8%) Query: 101 KEILMEKIKQYKE----LSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDN 156 K+++ EK Q KE L K + Q+ ++ N++KE+ N Sbjct: 2564 KQLISEKKTQNKEKTDKLFKEINDLTEELNSLEDDSENKELQSQIDELNEQINSVKEESN 2623 Query: 157 ALSVLQVKMKIMETTILDLQ---------EKINE---------KDQIIEAKNKATTXXXX 198 + K ++ LQ EK+ E KD + +N+ Sbjct: 2624 PQQTKENLQKELDDLNNKLQQMIEDEEENEKLKEEIDALKEELKDNKSQEENQQLKSQIS 2683 Query: 199 XXXXXXXXXXXXXEDT----KQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLE 254 +T K Q++++Q E+E D+ L K+I+S +I++ E Sbjct: 2684 ELQEQIKQKQNEISETENSLKSQISQLQNELKEKESERGDKSNSLYKEIDSLKEKINNQE 2743 Query: 255 EANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKG 314 NK + ++ + K QEL + +K + EEK + ++ Sbjct: 2744 IENKADSSQLSDLLKDLKKKLQELTEENETIKSKISEEKEKSKSEMAKLEEEKKSLNKE- 2802 Query: 315 SLEIANMTELTKKIE-----LLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPL 369 LE N E + +E L E LN + +Q N+E + KL+ + S L Sbjct: 2803 -LENVNDDEDKEMLEGEVSSLKETLNLK-KQINEEQKQKLSQEKEKLTEELSQLNDNEDL 2860 Query: 370 ISR-KSGRNTASKMKSPWSQLSS-ETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYV 427 + + K+K+ S L + L + ++K K L+ I+ L K++ +KE Sbjct: 2861 KKEIEQKKEELEKLKNDSSLLQELQDLKKQIEEKSEKQNPELLKQ-IEDLKKEISEKE-- 2917 Query: 428 ISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQ 487 SE D + L+ Q + + ME V + +E++ Q + Sbjct: 2918 -SENDLITGEKNTVEQQYNKLVEQRKY-LESTMEAAKK-KVSDLRQQCDELSMKNNQFRI 2974 Query: 488 ELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKL-----KLKQMQK 542 + E ++ +K IE++K EQ+ + ++E D + KL KL + Sbjct: 2975 DNEKEFQE--IKKSIEEIKGQREQLAKKHNE-DKRRAREYNTLARQKLTDAQQKLDAEKA 3031 Query: 543 TIDNFSK-VSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVD-YDSGRMIESDVYK 600 +N K +S+ K + L +E L QK ELE++ + D + R + ++ K Sbjct: 3032 KNENLLKMMSEQEKTVSNLEKESEDLEQKNKELEQQMTSTGDFSQDKIEELRKKKEELQK 3091 Query: 601 KMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADI-SQLQSDQVCSEI 659 E+ + ++ + L+++K L E+ L+ + +E + ++ +L+ D+ Sbjct: 3092 LNDELSQKQKQNIEQSNSLQNEKVTLSNEIESLKSSTEAMEKESTEMEKKLEEDKGIISE 3151 Query: 660 KSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMD 719 KS E+ L KE + LK + +L K + + D+ +K+ + ++ ++ Sbjct: 3152 KSKEKED----LEKKSKEQQEKSDKLKQEVAELQEKAKKITTENTDLNDKITD-LEISIS 3206 Query: 720 LTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRIC 779 ++ +K E+I + AK E++ +++ + K + R++ ++ + + +S I Sbjct: 3207 NAERRKKDLEEEIEKSSAKSLQEKEKELE-EIAEKKKKEVREMKKQH-KQNIRSLESSIS 3264 Query: 780 RLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEK 839 LE+ I +E+ + S +K++Q G L +++ A + I++ EL + ++ D D ++K Sbjct: 3265 LLEQDIKSLEEIQNS-SKKSEQEGLQLLDEKVA--DLKIKKFELED---IIADRDSELKK 3318 Query: 840 QLLEIEHENKELQKKN-QILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQT 898 E+ +NKEL + N QI + + D++ + K + +L E + Sbjct: 3319 WEKELLEKNKELSEVNRQIRALKGDKIDQIKEDIKDIDEEIESKKKKLNLNTVEDNDEEE 3378 Query: 899 QLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVT 958 + ES+ +I T + K E ED + + + + + + E+ K +V Sbjct: 3379 E----ESSKPKIF----TPTISKPSEQEDNKPKI--FVPTIPKQNEENKEENNKPKVFVP 3428 Query: 959 QLEAQLQEYKNNIENLNMNVEELNKMNLELIDK 991 + Q +E K E V K N E D+ Sbjct: 3429 VVPKQTEEQKKEEEKPKFFVPTTPKQNEENKDE 3461 >UniRef50_A2EMR6 Cluster: Viral A-type inclusion protein, putative; n=4; cellular organisms|Rep: Viral A-type inclusion protein, putative - Trichomonas vaginalis G3 Length = 2416 Score = 204 bits (498), Expect = 2e-50 Identities = 309/1532 (20%), Positives = 663/1532 (43%), Gaps = 142/1532 (9%) Query: 152 KEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXX 211 ++ +N V K++ +E T LQE+IN + K + Sbjct: 653 EDYENYKKVTNEKIQQLENTKRQLQEQINN-----QPKPEGNLAMLQKENEEYQRQINEL 707 Query: 212 EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDI---ESKDVRISSLEEANKLLEAARFEI- 267 +D K + K+ E + ++ E + L I E D + L + N L E+ Sbjct: 708 KDLKTEYLKLIEEKRETDEKYNKEIEELKDRINRGEGGDEVVEELAKENDELSKENEELK 767 Query: 268 -SLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTK 326 L+ K ++E+E+ +Q + E +IEE +E EL K Sbjct: 768 EKLKDIKSSEEIEELTNQIEELEKELNEKKEQLEQTENELTQQIEE---IEEEKSEELKK 824 Query: 327 KIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPL-----ISRKSGRNTASK 381 K E +E L +I + NKE+++ + + + + K+ L S+++ + T + Sbjct: 825 KNEEIERLQNEIEELNKEIKSLTEEIDDLQEKLENAKKEIQELQEYAEKSQENDKQTIDE 884 Query: 382 MKSPWSQLSSETLNQDTDKKI-------NKNEIAKLEMVIQSLNKDLVDKEYVISEKDTX 434 +K +L++ET D+D K+ + ++ LE I L ++ D + VI E++ Sbjct: 885 LKEK-LRLANETKVTDSDTKVLVESKEAAEQKVLLLEKEISDLKIEIEDLKSVIDEENEQ 943 Query: 435 XXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIK 494 + I +L+ E + + + N E + ++ K E LK +++E + Sbjct: 944 KVSNTEA----ENRIHELESEISELKKELDQNNNQQNDEKIEKLQKEIEDLKSVIDEENE 999 Query: 495 D-VNVKDLIEKLKSAEEQITQLNDEIDAAN--KNMIKVKSNHK----LKLKQMQKTIDNF 547 V+ + ++ E +I++L E+D N +N K++ K LK + +N Sbjct: 1000 QKVSNTEAENRIHELESEISELKKELDQNNNQQNDEKIEKLQKEIEDLKNELESSKAENE 1059 Query: 548 SKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDV-YKKMIEME 606 ++ KEI ++++E +L ++ L +EKG+ + ++D + + E + M E Sbjct: 1060 ELQNEFEKEIDQISQEKQNLESQIKYL-QEKGD-KSEIIDKLNQTIEELRAKVEHMFTQE 1117 Query: 607 NLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADI-SQLQSDQV-CSEIKSVHL 664 ++ E + I L+ + ++ + I ++K + E+ + ++ ++L++ + S++KS Sbjct: 1118 DIDEYK-SEIENLKQELSNIEKSKQISEEKSQDYEEIVHELENKLEAKETELSKLKS-DF 1175 Query: 665 EEQIDALSASKKELALVIENLKLDKEQLYGT----IKDLENDKEDIMNKLQNYIQENMDL 720 E+Q + K+ + + ++++K+ I LE D+ NKLQ+ I+ ++ Sbjct: 1176 EQQTREIETLKENITNLENEMEIEKKNRNSADNEKISHLEKQISDLQNKLQDKIKSQNEM 1235 Query: 721 TDKLEKMSAE---KISELLAKINHEEQSKIQTQFG-IDAKIQERDLYIENIESELSKYKS 776 +K ++ E K ++ + +H Q+KI++ + +E D N E +L+K Sbjct: 1236 VEKFKRDFQEMQAKDQKIREEESHASQAKIESLNALLKQSKEENDALKMNHEIKLNKISE 1295 Query: 777 RICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRV 836 LE+ + E L ++ + + K SE DE L + V Sbjct: 1296 FTKDLEQKVKSKEQEIELLTQQNSVCSKEINDLHKNNSELKKLSDE-------LQSENNV 1348 Query: 837 VEKQLLEIEHENKELQKKNQILLEENQ--NLQISLSDMQQHYNALVEKANRTDLAESEST 894 +E++L + E K LQ + + +NQ NL +S++ + N L EK E + T Sbjct: 1349 LEEKLKRLMSELKFLQ-ETSVKNTDNQITNLNSKISELSEEINILKEK-------EIKLT 1400 Query: 895 KYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDL---EIEFNTQIESAIRDKKVLNEKYE 951 K ++ + S +I +++ ++ Q ++EDL I + +E+ ++ KYE Sbjct: 1401 K---EIEKVTSEKNKIIQDNEEVVNQLMSDLEDLRRKNINLDELVENLRKEISEEKSKYE 1457 Query: 952 KNI----EYVTQLEAQLQEYKNNIENLNMNVEEL---NKMNLELIDKHV---QKQQTQSP 1001 ++ E + QL + E K E LN+ + +L N +N E + + + ++ +++ Sbjct: 1458 RDTTKLNETILQLNNTVFEIKKQNEQLNLTISDLSTSNNLNSEKVTQEILELNEKISKAK 1517 Query: 1002 DYTEQYINEINKLNALLKQKDEEIIALNQKIN-------NAQVSYMSMVSDYESKLAQFT 1054 + + I +LN L+ +EE L++ I N+ S+ + E + Sbjct: 1518 EENDNLSRHIEELNQQLESANEENSKLSKTIEEEKTKNLNSSEKSFSLEKEVEKLQEEKE 1577 Query: 1055 TKLENMEEEMQRVS-------------KQLLD-SKQHNEELQILVREQDDQIKELKET-- 1098 +E EEE ++ KQ ++ SK+ NE+L+ ++ E + +ELK T Sbjct: 1578 IFVEKSEEEKNKLKSEVTTLTEISANLKQEIEISKEQNEKLKSMLSEVESNNEELKHTIE 1637 Query: 1099 KLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQE---EEEFIQERS 1155 +L+ ++N +T+ + IE ++ D + ++ +E F ++ + Sbjct: 1638 ELSSQINDLQTQNDKVEKQIENLNKTIEEKDETINKMIANSDDSEKRDNEMKELFNKQNN 1697 Query: 1156 VLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVV---NQEQINQLKSKLEQLNTENDN 1212 + E S + ++ E + +++ LN E V+ +++ + L+ ++++ ++EN Sbjct: 1698 KINELSKLIESKTSENDKLLSEIKDLNKENEELAVLVDEKEDENHTLQVRIDEKDSENSQ 1757 Query: 1213 LLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLL 1272 L + ++++ + ++S + I EL K + + + K + E+K ++ Sbjct: 1758 LKTDLSDIENKLNSGKELLNHTIDELTKS-IESKSNENSKLMSAIDQLNKDLENK-NKIT 1815 Query: 1273 DSVQSSTQEETNKIVTMEQVT-----SLQNKLQDKEEHLRNLQEKYADVINQIEILRSEI 1327 + + + +E +K++ + +V L++ L D E + + + +IEI EI Sbjct: 1816 EEIANKNEENESKLLDLNKVVEELKKQLEHVLIDNESEKQEKSDTEQKLREEIEIKEKEI 1875 Query: 1328 EDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNI-NEENAQLKKSSXXXXX 1386 + K D E + + I I ++ ++ K Sbjct: 1876 DKLKKQNDQQIDHFTTQISQINDDHNNEIDQINEDYQTQIDQIKHDHEREMNKLKENHQH 1935 Query: 1387 XXXXXXXRVNDAEAKVLE-----------LTHQLELKDSEIYQKTH-EYTITLTQRNDEF 1434 + D E + E L Q+ K+ E +K + ++T +++ N+ Sbjct: 1936 EIESYKQNIEDLEHQFKEIGCKNDEYFNNLIDQINTKNKEEIEKLNVQFTSQISEINENH 1995 Query: 1435 ENVRQQL-VEYEKRIEDLTYEKESELAIL-RLKMHENANHYETMQKESEIERVKLIEELN 1492 +N +Q+ ++ ++ I + Y+ S+++ L LK +N YE Q S E+ K I+ LN Sbjct: 1996 KNEIEQINIKNQEEIMKINYQFTSQISELNELKEEDNKKIYELCQDNS--EKKKEIDRLN 2053 Query: 1493 VKITESVSLNKQVAELN-KALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASS 1551 +I E ++N Q N K L E+ ++ +++++ EI LND++T ++ + Sbjct: 2054 KEIEEYHNMNHQRENDNEKNLIEKDEIIQKLNKTIKDKQREIDCLNDQLTE-KDESSEEN 2112 Query: 1552 SKIQKHVSFASDTKQGRDEQLDN--TMNKELL 1581 K+ K +S ++ +++++ N N+E+L Sbjct: 2113 DKLVKFISTLKESLSSKEKEIQNLKKQNEEIL 2144 Score = 194 bits (473), Expect = 2e-47 Identities = 286/1348 (21%), Positives = 593/1348 (43%), Gaps = 130/1348 (9%) Query: 315 SLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKS 374 S++ A + EL KK E + QI NKEL++ L + E A + ++ K+ Sbjct: 563 SIQKARIDELEKKFEQTQ----QIIDENKELKDTLNLLQEEFHAYEMTIQSYETTLNEKN 618 Query: 375 GRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTX 434 N + K S NQ+TDKK ++NEI ++ N V E + ++T Sbjct: 619 QENDKLRQKLE----SKGIFNQETDKK-DENEIKLKQLNEDYENYKKVTNEKIQQLENTK 673 Query: 435 XXXXXXXXX--GKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDE 492 + +A LQ E++++ + + TE + I + +E ++ N E Sbjct: 674 RQLQEQINNQPKPEGNLAMLQKENEEYQRQINELK-DLKTEYLKLIEEKRE-TDEKYNKE 731 Query: 493 IKDVNVKDLIEKLKSAEEQITQL---NDEIDAANKNM-IKVKS-NHKLKLKQMQKTIDNF 547 I++ +KD I + + +E + +L NDE+ N+ + K+K +++++ I+ Sbjct: 732 IEE--LKDRINRGEGGDEVVEELAKENDELSKENEELKEKLKDIKSSEEIEELTNQIEEL 789 Query: 548 SKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMEN 607 K + KE + TE + L+Q++ E+EEEK +L + + R +++++ + E+++ Sbjct: 790 EKELNEKKEQLEQTE--NELTQQIEEIEEEKSE-ELKKKNEEIER-LQNEIEELNKEIKS 845 Query: 608 LAETRLKAISLLESQKFDLVQELHILQQK--------YDEVEDKL----------ADISQ 649 L E LE+ K + +QEL +K DE+++KL +D Sbjct: 846 LTEEIDDLQEKLENAKKE-IQELQEYAEKSQENDKQTIDELKEKLRLANETKVTDSDTKV 904 Query: 650 LQSDQVCSEIKSVHLEEQIDALSASKKELALVIE---NLKLDKEQLYGTIKDLENDKEDI 706 L + +E K + LE++I L ++L VI+ K+ + I +LE++ ++ Sbjct: 905 LVESKEAAEQKVLLLEKEISDLKIEIEDLKSVIDEENEQKVSNTEAENRIHELESEISEL 964 Query: 707 MNKL-QNYIQENMDLTDKLEK-----------MSAEKISELLAKIN-HEEQSKI-QTQFG 752 +L QN Q+N + +KL+K + +K+S A+ HE +S+I + + Sbjct: 965 KKELDQNNNQQNDEKIEKLQKEIEDLKSVIDEENEQKVSNTEAENRIHELESEISELKKE 1024 Query: 753 IDA-KIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQ--EK 809 +D Q+ D IE ++ E+ K+ LE S A E+ + E++ DQ+ Q E Sbjct: 1025 LDQNNNQQNDEKIEKLQKEIEDLKN---ELESSKAENEELQNEFEKEIDQISQEKQNLES 1081 Query: 810 QKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLL---EIEHENKELQKKNQILLEENQNLQ 866 Q Y + + E++++L ++ R + + +I+ E++ Q L ++ Q Sbjct: 1082 QIKYLQEKGDKSEIIDKLNQTIEELRAKVEHMFTQEDIDEYKSEIENLKQELSNIEKSKQ 1141 Query: 867 ISLSDMQQHYNALVEKANRTDLAESESTK----YQTQLRDLESNLKRITHEHQTLIVQKK 922 IS Q + + E N+ + E+E +K ++ Q R++E+ + IT+ + ++KK Sbjct: 1142 ISEEKSQDYEEIVHELENKLEAKETELSKLKSDFEQQTREIETLKENITNLENEMEIEKK 1201 Query: 923 KEIEDLEIEFNTQIESAIRD-KKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEEL 981 + E + +E I D + L +K + E V + + QE + + + Sbjct: 1202 NR-NSADNEKISHLEKQISDLQNKLQDKIKSQNEMVEKFKRDFQEMQAKDQKIREEESHA 1260 Query: 982 NKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMS 1041 ++ +E ++ +++ + ++ + ++NK++ K ++++ + Q+I S Sbjct: 1261 SQAKIESLNALLKQSKEENDALKMNHEIKLNKISEFTKDLEQKVKSKEQEI-ELLTQQNS 1319 Query: 1042 MVSDYESKLAQFTTKLENMEEEMQRVSKQLLDS-KQHNEELQIL----VREQDDQIKEL- 1095 + S + L + ++L+ + +E+Q + L + K+ EL+ L V+ D+QI L Sbjct: 1320 VCSKEINDLHKNNSELKKLSDELQSENNVLEEKLKRLMSELKFLQETSVKNTDNQITNLN 1379 Query: 1096 -KETKLTFEMNIPKTEGMIISSTIEPMSDDANNV---------DXXXXXXXXXXXXLKVQ 1145 K ++L+ E+NI K + + ++ IE ++ + N + + + Sbjct: 1380 SKISELSEEINILKEKEIKLTKEIEKVTSEKNKIIQDNEEVVNQLMSDLEDLRRKNINLD 1439 Query: 1146 E-----EEEFIQERSVLQEQSAKLNTELQECYTKIIQL----ETLN---TELTGHDVVNQ 1193 E +E +E+S + + KLN + + + ++ E LN ++L+ + +N Sbjct: 1440 ELVENLRKEISEEKSKYERDTTKLNETILQLNNTVFEIKKQNEQLNLTISDLSTSNNLNS 1499 Query: 1194 EQINQ----LKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREAD 1249 E++ Q L K+ + ENDNL + EL + SA + E ++L K ++ + Sbjct: 1500 EKVTQEILELNEKISKAKEENDNLSRHIEELNQQLESANE----ENSKLSKTIEEEKTKN 1555 Query: 1250 FQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVT-MEQVTSLQNKLQDKEEHLRN 1308 +E ++ K ++ + ++EE NK+ + + +T + L+ + E + Sbjct: 1556 LNSSEKSFSLEKEV--EKLQEEKEIFVEKSEEEKNKLKSEVTTLTEISANLKQEIEISKE 1613 Query: 1309 LQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSIL 1368 EK +++++E E++ DL+T+N ++ E Sbjct: 1614 QNEKLKSMLSEVESNNEELK-----------HTIEELSSQINDLQTQNDKVEKQIENLNK 1662 Query: 1369 NINEENAQLKK---SSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTI 1425 I E++ + K +S N K+ EL+ +E K SE + E Sbjct: 1663 TIEEKDETINKMIANSDDSEKRDNEMKELFNKQNNKINELSKLIESKTSENDKLLSEIK- 1721 Query: 1426 TLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERV 1485 L + N+E + + + ++ EK+SE + L+ + + N + ++ Sbjct: 1722 DLNKENEELAVLVDEKEDENHTLQVRIDEKDSENSQLKTDLSDIENKLNSGKELLNHTID 1781 Query: 1486 KLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQN 1545 +L + + K E+ L + +LNK LE + T E+ E E +++ LN + L+ Sbjct: 1782 ELTKSIESKSNENSKLMSAIDQLNKDLENKNKITEEIANKNEENESKLLDLNKVVEELKK 1841 Query: 1546 MVRASSSKIQKHVSFASDTKQGRDEQLD 1573 + + SDT+Q E+++ Sbjct: 1842 QLEHVLIDNESEKQEKSDTEQKLREEIE 1869 Score = 172 bits (418), Expect = 8e-41 Identities = 295/1473 (20%), Positives = 628/1473 (42%), Gaps = 129/1473 (8%) Query: 212 EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIES-KDVRISSLEEANKLLEAARFEI--- 267 E+ Q+ ++++ + + + + L + IE ++ + L++ N+ +E + EI Sbjct: 780 EELTNQIEELEKELNEKKEQLEQTENELTQQIEEIEEEKSEELKKKNEEIERLQNEIEEL 839 Query: 268 SLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEE-KGSLEIANMTELTK 326 + E L +E++ L + + + +K I+E K L +AN T++T Sbjct: 840 NKEIKSLTEEIDDLQEKLENAKKEIQELQEYAEKSQENDKQTIDELKEKLRLANETKVTD 899 Query: 327 K-IELLEHLNCQIRQTNKELENKLATMGTESKAVSSP-SKKGSPLISRKSGRNTASKMKS 384 ++L Q LE +++ + E + + S ++ +S N +++S Sbjct: 900 SDTKVLVESKEAAEQKVLLLEKEISDLKIEIEDLKSVIDEENEQKVSNTEAENRIHELES 959 Query: 385 PWSQLSSE---TLNQDTDKKINK--NEIAKLEMVIQSLNKDLV---DKEYVISEKDTXXX 436 S+L E NQ D+KI K EI L+ VI N+ V + E I E ++ Sbjct: 960 EISELKKELDQNNNQQNDEKIEKLQKEIEDLKSVIDEENEQKVSNTEAENRIHELESEIS 1019 Query: 437 XXXXXXXGK-----DTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELND 491 D I +LQ E + ++ N E NE K +Q+ QE + Sbjct: 1020 ELKKELDQNNNQQNDEKIEKLQKEIED-LKNELESSKAENEELQNEFEKEIDQISQEKQN 1078 Query: 492 EIKDVNVKDLIEKLKSAE--EQITQLNDEIDAANKNMIKVKS--NHKLKLKQMQKTIDNF 547 + +K L EK +E +++ Q +E+ A ++M + +K +++ +++ + N Sbjct: 1079 --LESQIKYLQEKGDKSEIIDKLNQTIEELRAKVEHMFTQEDIDEYKSEIENLKQELSNI 1136 Query: 548 SKVSDSNKEIVRLTEELHH-----LSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKM 602 K ++E + EE+ H L K EL + K + + + ++ + +++ +M Sbjct: 1137 EKSKQISEEKSQDYEEIVHELENKLEAKETELSKLKSDFEQQTREIETLKENITNLENEM 1196 Query: 603 -IEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLA-DISQLQS-DQVCSEI 659 IE +N + IS LE Q DL +L + +E+ +K D ++Q+ DQ E Sbjct: 1197 EIEKKNRNSADNEKISHLEKQISDLQNKLQDKIKSQNEMVEKFKRDFQEMQAKDQKIREE 1256 Query: 660 KSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTI----KDLENDKEDIMNKLQNYIQ 715 +S + +I++L+A K+ + LK++ E I KDLE + +++ Q Sbjct: 1257 ESHASQAKIESLNALLKQSKEENDALKMNHEIKLNKISEFTKDLEQKVKSKEQEIELLTQ 1316 Query: 716 ENMDLTDK---LEKMSAE--KISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESE 770 +N + + L K ++E K+S+ L N+ + K++ +QE ++N +++ Sbjct: 1317 QNSVCSKEINDLHKNNSELKKLSDELQSENNVLEEKLKRLMSELKFLQETS--VKNTDNQ 1374 Query: 771 LSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVL 830 ++ S+I L E I +++++ L ++ +++ S EK K + ++L++ L L Sbjct: 1375 ITNLNSKISELSEEINILKEKEIKLTKEIEKVTS---EKNKIIQDNEEVVNQLMSDLEDL 1431 Query: 831 ----MDHDRVVEKQLLEIEHENKELQ----KKNQILLE----------ENQNLQISLSDM 872 ++ D +VE EI E + + K N+ +L+ +N+ L +++SD+ Sbjct: 1432 RRKNINLDELVENLRKEISEEKSKYERDTTKLNETILQLNNTVFEIKKQNEQLNLTISDL 1491 Query: 873 QQHYNALVEKANRTDL--------AESESTKYQTQLRDLESNLKRITHEH----QTLIVQ 920 N EK + L A+ E+ + +L L+ E+ +T+ + Sbjct: 1492 STSNNLNSEKVTQEILELNEKISKAKEENDNLSRHIEELNQQLESANEENSKLSKTIEEE 1551 Query: 921 KKKEIEDLEIEFNTQ--IESAIRDKKVLNEKYE--KN-----IEYVTQLEAQLQEY---- 967 K K + E F+ + +E +K++ EK E KN + +T++ A L++ Sbjct: 1552 KTKNLNSSEKSFSLEKEVEKLQEEKEIFVEKSEEEKNKLKSEVTTLTEISANLKQEIEIS 1611 Query: 968 KNNIENLNMNVEELNKMNLELIDKH-VQKQQTQSPDYTEQ---YINEINKLNALLKQKDE 1023 K E L + E+ N EL KH +++ +Q D Q +I LN +++KDE Sbjct: 1612 KEQNEKLKSMLSEVESNNEEL--KHTIEELSSQINDLQTQNDKVEKQIENLNKTIEEKDE 1669 Query: 1024 EI---IALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEE 1080 I IA + + + +K+ + + +E+ E ++ ++ D + NEE Sbjct: 1670 TINKMIANSDDSEKRDNEMKELFNKQNNKINELSKLIESKTSENDKLLSEIKDLNKENEE 1729 Query: 1081 LQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXX 1140 L +LV E++D+ T ++ I + + S +SD N ++ Sbjct: 1730 LAVLVDEKEDE-------NHTLQVRIDEKDSEN-SQLKTDLSDIENKLNSGKELLNHTID 1781 Query: 1141 XLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLK 1200 L E + E S L +LN +L+ ++ N E + + + +LK Sbjct: 1782 ELTKSIESKS-NENSKLMSAIDQLNKDLENKNKITEEIANKNEENESKLLDLNKVVEELK 1840 Query: 1201 SKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQRE---ADFQKTEHEL 1257 +LE + +N++ ++ + ++ + EI +L KQ+ Q + + + Sbjct: 1841 KQLEHVLIDNESEKQEKSDTEQKLREEIEIKEKEIDKLKKQNDQQIDHFTTQISQINDDH 1900 Query: 1258 RVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQ--VTSLQNKLQDKEEHLRNL----QE 1311 ++ Y+ +D ++ + E NK+ Q + S + ++D E + + E Sbjct: 1901 NNEIDQINEDYQTQIDQIKHDHEREMNKLKENHQHEIESYKQNIEDLEHQFKEIGCKNDE 1960 Query: 1312 KYADVINQIEIL-RSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQS-YKQMQEQSILN 1369 + ++I+QI + EIE V F + +NQ ++ Q Sbjct: 1961 YFNNLIDQINTKNKEEIEKLNVQFTSQISEINENHKNEIEQINIKNQEEIMKINYQFTSQ 2020 Query: 1370 INEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQ 1429 I+E N +LK+ ++ + ++ L ++E + +Q+ ++ L + Sbjct: 2021 ISELN-ELKEEDNKKIYELCQDN---SEKKKEIDRLNKEIEEYHNMNHQRENDNEKNLIE 2076 Query: 1430 RNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIE 1489 +++ + + + + + ++ I+ L ++ +E + + T+ KES + K I+ Sbjct: 2077 KDEIIQKLNKTIKDKQREIDCLN-DQLTEKDESSEENDKLVKFISTL-KESLSSKEKEIQ 2134 Query: 1490 ELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEI-EIVTLNDEITNLQNMVR 1548 L + E + N + LN+ ++ + NE + +EI ++ T N ++ N + Sbjct: 2135 NLKKQNEEILKQNNDLKSLNEQQNDD-KQNNENDIEIMKKEIMKLRTENKDLKNQVSQQH 2193 Query: 1549 ASSSKIQKHVSFASDTKQGRDEQLDNTMNKELL 1581 + K+ K + + ++ ++L N + ++ Sbjct: 2194 KALVKLAKSLENKNKAEEKLKQELQNISKQNIV 2226 Score = 165 bits (401), Expect = 9e-39 Identities = 303/1471 (20%), Positives = 647/1471 (43%), Gaps = 123/1471 (8%) Query: 169 ETTILDLQEKINE-KDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIA 227 E I +L+ +I+E K ++ + N+ E +K + ++Q F Sbjct: 1008 ENRIHELESEISELKKELDQNNNQQNDEKIEKLQKEIEDLKNELESSKAENEELQNEFEK 1067 Query: 228 MEAEWKDEKQRL---LKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXX 284 + EKQ L +K ++ K + +++ N+ +E R ++ EH +++++ Sbjct: 1068 EIDQISQEKQNLESQIKYLQEKGDKSEIIDKLNQTIEELRAKV--EHMFTQEDIDEYKSE 1125 Query: 285 XXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKE 344 + K + EEK++ E+ E+ N E K+ EL + L Q +E Sbjct: 1126 IENLKQELSNIEKS--KQISEEKSQDYEEIVHELENKLE-AKETELSK-LKSDFEQQTRE 1181 Query: 345 LENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMK-SPWSQLSSETLNQDTDKKIN 403 +E T + +++ + + K RN+A K S + S+ N+ DK + Sbjct: 1182 IE-------TLKENITNLENE---MEIEKKNRNSADNEKISHLEKQISDLQNKLQDKIKS 1231 Query: 404 KNE-IAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQ--QHM 460 +NE + K + Q + K+ I E+++ + L+ Q + E+ + Sbjct: 1232 QNEMVEKFKRDFQEMQA----KDQKIREEESHASQAKIESL--NALLKQSKEENDALKMN 1285 Query: 461 EGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEID 520 L + T+D+ + K +EQ + EL + V K+ I L ++ +L+DE+ Sbjct: 1286 HEIKLNKISEFTKDLEQKVKSKEQ-EIELLTQQNSVCSKE-INDLHKNNSELKKLSDELQ 1343 Query: 521 AANKNMIKVKSNHKL-KLKQMQKT-IDNF-SKVSDSNKEIVRLTEELHHLSQKVAELEEE 577 + N N+++ K + +LK +Q+T + N +++++ N +I L+EE++ L +K +L +E Sbjct: 1344 SEN-NVLEEKLKRLMSELKFLQETSVKNTDNQITNLNSKISELSEEINILKEKEIKLTKE 1402 Query: 578 KGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKY 637 + V + ++I+ + M +L + R K I+L E + +L +E+ + KY Sbjct: 1403 -----IEKVTSEKNKIIQDNEEVVNQLMSDLEDLRRKNINLDELVE-NLRKEISEEKSKY 1456 Query: 638 DEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKE--QLYGT 695 + KL + + LQ + EIK + EQ++ L+ S + + + K+ +E +L Sbjct: 1457 ERDTTKLNE-TILQLNNTVFEIKKQN--EQLN-LTISDLSTSNNLNSEKVTQEILELNEK 1512 Query: 696 IKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDA 755 I + + +++ ++ Q+ ++ K+S E +N E+S + ++ Sbjct: 1513 ISKAKEENDNLSRHIEELNQQLESANEENSKLSKTIEEEKTKNLNSSEKS-FSLEKEVEK 1571 Query: 756 KIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSE 815 +E+++++E E E +K KS + L E A ++ + + ++L S L E + E Sbjct: 1572 LQEEKEIFVEKSEEEKNKLKSEVTTLTEISANLKQEIEISKEQNEKLKSMLSEVESNNEE 1631 Query: 816 YTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQI---LLEENQNLQISLSDM 872 +EL +++ L + VEKQ IE+ NK +++K++ ++ + + + ++M Sbjct: 1632 LKHTIEELSSQINDLQTQNDKVEKQ---IENLNKTIEEKDETINKMIANSDDSEKRDNEM 1688 Query: 873 QQHYNALVEKANR-TDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIE 931 ++ +N K N + L ES++++ L +++ +L + E L+ +K+ E L++ Sbjct: 1689 KELFNKQNNKINELSKLIESKTSENDKLLSEIK-DLNKENEELAVLVDEKEDENHTLQVR 1747 Query: 932 F------NTQIESAIRD-KKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKM 984 N+Q+++ + D + LN E + +L ++ N L +++LNK Sbjct: 1748 IDEKDSENSQLKTDLSDIENKLNSGKELLNHTIDELTKSIESKSNENSKLMSAIDQLNK- 1806 Query: 985 NLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVS 1044 +LE +K + ++ + E + ++NK+ LK++ E ++ N+ S S Sbjct: 1807 DLENKNK-ITEEIANKNEENESKLLDLNKVVEELKKQLEHVLIDNE-------SEKQEKS 1858 Query: 1045 DYESKLAQFTTKLENMEEEMQRVSKQLLDSKQH-NEELQILVREQDDQIKELKETKLTFE 1103 D E KL + ++E E+E+ ++ KQ H ++ + + +++I ++ E T Sbjct: 1859 DTEQKLRE---EIEIKEKEIDKLKKQNDQQIDHFTTQISQINDDHNNEIDQINEDYQTQI 1915 Query: 1104 MNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEF----IQERSVLQE 1159 I ++ E + + + + +E F Q + +E Sbjct: 1916 DQIKHDHEREMNKLKENHQHEIESYKQNIEDLEHQFKEIGCKNDEYFNNLIDQINTKNKE 1975 Query: 1160 QSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLK-------SKLEQLNTENDN 1212 + KLN + ++I E E+ ++ NQE+I ++ S+L +L E++ Sbjct: 1976 EIEKLNVQFTSQISEI--NENHKNEIEQINIKNQEEIMKINYQFTSQISELNELKEEDNK 2033 Query: 1213 LLSTVAELRSSISSAVDQRGFEIAELW----------KQHLAQREADFQKTEHELRVQLS 1262 + + + S +D+ EI E +++L +++ QK ++ + Sbjct: 2034 KIYELCQDNSEKKKEIDRLNKEIEEYHNMNHQRENDNEKNLIEKDEIIQKLNKTIKDKQR 2093 Query: 1263 AFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEI 1322 + +QL + +SS EE +K+V +++L+ L KE+ ++NL+++ +++ Q Sbjct: 2094 EIDCLNDQLTEKDESS--EENDKLVKF--ISTLKESLSSKEKEIQNLKKQNEEILKQNND 2149 Query: 1323 LRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQM--QEQSILNINEENAQLKKS 1380 L+S + +++ LRTEN+ K Q+ L ++ + K Sbjct: 2150 LKS-LNEQQNDDKQNNENDIEIMKKEIMKLRTENKDLKNQVSQQHKALVKLAKSLENKNK 2208 Query: 1381 SXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQR---NDEFENV 1437 + + N + + +LT ++ KD+++ + E T L + + Sbjct: 2209 AEEKLKQELQNISKQNIVKNEEDKLTLLVKDKDNQLQRCRKELTNALQKAALYRAGLRSS 2268 Query: 1438 RQQLVEYEKRIEDLTYEKESE------LAILRLKMHENANHYETMQKESEIERVKLIEEL 1491 ++Q++E +K IED SE LR + A ET ++ EIE V+L EL Sbjct: 2269 QKQIIEIKKEIEDFKSSVSSEDILHERCLFLRARPALLAALTETETQKGEIEAVEL--EL 2326 Query: 1492 NVKITESVSLNKQVAELNKALEEEVAKTNEM--QTALENQEIEIVTLNDEITNLQNMVRA 1549 N K +L+ + E+ KT ++ +TA+ +E ++ + ++ V+ Sbjct: 2327 NDTKDSLAKALKDNRDLSSHI-VEMRKTIKLLKKTAITLEE-KVKEKDSGREQIEEKVKE 2384 Query: 1550 SSSKIQKHVSFASDTKQGRDEQLDNTMNKEL 1580 K + + Q R++ L N M K+L Sbjct: 2385 LEKKNSSALRLIGELWQ-RNQTLINAMPKDL 2414 Score = 163 bits (395), Expect = 5e-38 Identities = 252/1242 (20%), Positives = 543/1242 (43%), Gaps = 121/1242 (9%) Query: 392 ETLNQDTDKKINKNEIAKLEMV-IQSLNKDLVDKEYVISE----KDTXXX------XXXX 440 + L DT+ ++N + + ++ I L K + +I E KDT Sbjct: 546 DNLLNDTEIQVNDSALVSIQKARIDELEKKFEQTQQIIDENKELKDTLNLLQEEFHAYEM 605 Query: 441 XXXGKDTLIAQLQLEH---QQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVN 497 +T + + E+ +Q +E + + T+ +D NEI +LKQ LN++ ++ Sbjct: 606 TIQSYETTLNEKNQENDKLRQKLESKGIFNQETDKKDENEI-----KLKQ-LNEDYENYK 659 Query: 498 VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEI 557 K EK++ E QL ++I+ N K + N + K+ ++ +++ D E Sbjct: 660 -KVTNEKIQQLENTKRQLQEQIN----NQPKPEGNLAMLQKENEEYQRQINELKDLKTEY 714 Query: 558 VRLTEELHHLSQKV-AELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAI 616 ++L EE +K E+EE K + + G + ++ K+ E+ E + + Sbjct: 715 LKLIEEKRETDEKYNKEIEELKDRINRG----EGGDEVVEELAKENDELSKENEELKEKL 770 Query: 617 SLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKK 676 ++S + ++ + + +++ E+ +K + Q +++ + +I+ + EE+ + L + Sbjct: 771 KDIKSSE-EIEELTNQIEELEKELNEKKEQLEQTENE-LTQQIEEIE-EEKSEELKKKNE 827 Query: 677 ELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQN---YIQENMDLTDKLEKMSAEKIS 733 E IE L+ + E+L IK L + +D+ KL+N IQE + +K ++ + I Sbjct: 828 E----IERLQNEIEELNKEIKSLTEEIDDLQEKLENAKKEIQELQEYAEKSQENDKQTID 883 Query: 734 ELLAKINHEEQSKI---QTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMED 790 EL K+ ++K+ T+ +++K + + + +E E+S K I L+ I + Sbjct: 884 ELKEKLRLANETKVTDSDTKVLVESK-EAAEQKVLLLEKEISDLKIEIEDLKSVIDEENE 942 Query: 791 RRYS---LERKADQLGSYLQEKQKAYSEYTIQE-DELVNRLAVLMDHDRVVEKQLLEIEH 846 ++ S E + +L S + E +K + Q+ DE + +L ++ K +++ E+ Sbjct: 943 QKVSNTEAENRIHELESEISELKKELDQNNNQQNDEKIEKLQKEIED----LKSVIDEEN 998 Query: 847 ENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESN 906 E K + + + E L+ +S++++ + N + + K Q ++ DL++ Sbjct: 999 EQKVSNTEAENRIHE---LESEISELKKELD-----QNNNQQNDEKIEKLQKEIEDLKNE 1050 Query: 907 LKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIR------DKKVLNEKYEKNIEYVTQ- 959 L+ E++ L + +KEI+ + E +ES I+ DK + +K + IE + Sbjct: 1051 LESSKAENEELQNEFEKEIDQISQE-KQNLESQIKYLQEKGDKSEIIDKLNQTIEELRAK 1109 Query: 960 -----LEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQT--QSPDYTEQYINEIN 1012 + + EYK+ IENL + + K +K ++ + + E E++ Sbjct: 1110 VEHMFTQEDIDEYKSEIENLKQELSNIEKSKQISEEKSQDYEEIVHELENKLEAKETELS 1169 Query: 1013 KLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLL 1072 KL + +Q+ EI L + I N + M + +++ + K+ ++E+++ + +L Sbjct: 1170 KLKSDFEQQTREIETLKENITNLE---NEMEIEKKNRNSADNEKISHLEKQISDLQNKLQ 1226 Query: 1073 DS-KQHNEELQILVRE-QDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDX 1130 D K NE ++ R+ Q+ Q K+ K + + K E + +DA ++ Sbjct: 1227 DKIKSQNEMVEKFKRDFQEMQAKDQKIREEESHASQAKIESLNALLKQSKEENDALKMNH 1286 Query: 1131 XXXXXXXXXXXLKVQEE-EEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHD 1189 ++++ + QE +L +Q++ + E+ + + +L+ L+ EL + Sbjct: 1287 EIKLNKISEFTKDLEQKVKSKEQEIELLTQQNSVCSKEINDLHKNNSELKKLSDELQSEN 1346 Query: 1190 VVNQEQINQLKSKLEQL------NTEND--NLLSTVAELRSSISSAVDQRGFEIAELWKQ 1241 V +E++ +L S+L+ L NT+N NL S ++EL I + + ++ ++ + ++ Sbjct: 1347 NVLEEKLKRLMSELKFLQETSVKNTDNQITNLNSKISELSEEI-NILKEKEIKLTKEIEK 1405 Query: 1242 HLAQREADFQKTEHELRVQLSAFES------KYEQLLDSVQSSTQEETNKIVTMEQVTSL 1295 +++ Q E + +S E ++L+++++ EE +K E+ T+ Sbjct: 1406 VTSEKNKIIQDNEEVVNQLMSDLEDLRRKNINLDELVENLRKEISEEKSK---YERDTT- 1461 Query: 1296 QNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTE 1355 KL + L N + Q+ + S++ + E Sbjct: 1462 --KLNETILQLNNTVFEIKKQNEQLNLTISDLSTSNNLNSEKVTQEILELNEKISKAKEE 1519 Query: 1356 NQSYKQMQE---QSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLEL- 1411 N + + E Q + + NEEN++L K+ + E +V +L + E+ Sbjct: 1520 NDNLSRHIEELNQQLESANEENSKLSKTIEEEKTKNLNSSEKSFSLEKEVEKLQEEKEIF 1579 Query: 1412 --KDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHEN 1469 K E K TLT+ + + + E ++++ + E ES L+ + E Sbjct: 1580 VEKSEEEKNKLKSEVTTLTEISANLKQEIEISKEQNEKLKSMLSEVESNNEELKHTIEEL 1639 Query: 1470 ANHYETMQKESEIERVKLIEELNVKITE-SVSLNKQVAELNKALEEEVAKTNEMQTALEN 1528 ++ +Q +++ + K IE LN I E ++NK +A ++ + NEM+ Sbjct: 1640 SSQINDLQTQND-KVEKQIENLNKTIEEKDETINKMIAN----SDDSEKRDNEMKELFNK 1694 Query: 1529 QEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDE 1570 Q N++I L ++ + +S+ K +S D + +E Sbjct: 1695 Q-------NNKINELSKLIESKTSENDKLLSEIKDLNKENEE 1729 Score = 151 bits (365), Expect = 2e-34 Identities = 268/1308 (20%), Positives = 551/1308 (42%), Gaps = 126/1308 (9%) Query: 87 VPGISESLANTLKQKEILMEKIKQYKEL------SKRSSTTIVRXXXXXXXXXXXXXXXQ 140 + + + L+N K K+I EK + Y+E+ + T + Sbjct: 1126 IENLKQELSNIEKSKQISEEKSQDYEEIVHELENKLEAKETELSKLKSDFEQQTREIETL 1185 Query: 141 LGDVTHLSNTIK-EKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXX 199 ++T+L N ++ EK N S K+ +E I DLQ K+ +K I+++N+ Sbjct: 1186 KENITNLENEMEIEKKNRNSADNEKISHLEKQISDLQNKLQDK---IKSQNEMVEKFKRD 1242 Query: 200 XXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSL-EEANK 258 E+ E+ A+ + K+E L + E K +IS ++ + Sbjct: 1243 FQEMQAKDQKIREEESHASQAKIESLNALLKQSKEENDALKMNHEIKLNKISEFTKDLEQ 1302 Query: 259 LLEAARFEISL---EHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEK-----TEI 310 +++ EI L ++S ++E+ L QS EEK +E+ Sbjct: 1303 KVKSKEQEIELLTQQNSVCSKEINDLHKNNSELKKLSDEL--QSENNVLEEKLKRLMSEL 1360 Query: 311 EEKGSLEIAN----MTELTKKI-ELLEHLNCQIRQTNKELENKLATMGTE-SKAVSSPSK 364 + + N +T L KI EL E +N +++ +L ++ + +E +K + + Sbjct: 1361 KFLQETSVKNTDNQITNLNSKISELSEEINI-LKEKEIKLTKEIEKVTSEKNKIIQDNEE 1419 Query: 365 KGSPLIS-----RKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNK 419 + L+S R+ N +++ ++S E + D I +L + + K Sbjct: 1420 VVNQLMSDLEDLRRKNINLDELVENLRKEISEEKSKYERDTTKLNETILQLNNTVFEIKK 1479 Query: 420 DLVDKEYVISEKDTXXXXXXXXXXGK----DTLIAQLQLEH---QQHMEGPSLIHVGTNT 472 IS+ T + + I++ + E+ +H+E + N Sbjct: 1480 QNEQLNLTISDLSTSNNLNSEKVTQEILELNEKISKAKEENDNLSRHIEELNQQLESANE 1539 Query: 473 EDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKL--------KSAEEQITQLNDEIDAANK 524 E+ ++E+ + LN K +++ +EKL + +EE+ +L E+ + Sbjct: 1540 ENSKLSKTIEEEKTKNLNSSEKSFSLEKEVEKLQEEKEIFVEKSEEEKNKLKSEVTTLTE 1599 Query: 525 NMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLH 584 +K ++ +Q +K S+V +N+E+ EE LS ++ +L+ + ++ Sbjct: 1600 ISANLKQEIEISKEQNEKLKSMLSEVESNNEELKHTIEE---LSSQINDLQTQNDKVEKQ 1656 Query: 585 LVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQEL-HILQQKYDEVEDK 643 + + + + + KMI + +E R + L +++ + + EL +++ K E + Sbjct: 1657 IENLNKTIEEKDETINKMIANSDDSEKRDNEMKELFNKQNNKINELSKLIESKTSENDKL 1716 Query: 644 LADISQLQSDQ----VCSEIK-------SVHLEEQIDALSASKKELALVIENLKLDKEQL 692 L++I L + V + K V ++E+ S K +L+ + L KE L Sbjct: 1717 LSEIKDLNKENEELAVLVDEKEDENHTLQVRIDEKDSENSQLKTDLSDIENKLNSGKELL 1776 Query: 693 YGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFG 752 TI +L E N+ + L LE + KI+E +A N E +SK+ Sbjct: 1777 NHTIDELTKSIESKSNENSKLMSAIDQLNKDLE--NKNKITEEIANKNEENESKLLDLNK 1834 Query: 753 I--DAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKAD-QLGSYLQEK 809 + + K Q + I+N ESE + +L E I + E L+++ D Q+ + + Sbjct: 1835 VVEELKKQLEHVLIDN-ESEKQEKSDTEQKLREEIEIKEKEIDKLKKQNDQQIDHFTTQI 1893 Query: 810 QKAYSEYTIQEDELVNRLAVLMD---HDRVVEKQLLEIEHENKELQKKNQILLEENQNLQ 866 + ++ + D++ +D HD E L+ H+++ K I E+Q + Sbjct: 1894 SQINDDHNNEIDQINEDYQTQIDQIKHDHEREMNKLKENHQHEIESYKQNIEDLEHQFKE 1953 Query: 867 ISLSDMQQHYNALVEKANRTDLAESE--STKYQTQLRDLESNLKRITHEHQTLIVQKKKE 924 I + +++N L+++ N + E E + ++ +Q+ ++ N K +E + + ++ ++E Sbjct: 1954 IGCKN-DEYFNNLIDQINTKNKEEIEKLNVQFTSQISEINENHK---NEIEQINIKNQEE 2009 Query: 925 IEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKM 984 I + +F +QI LNE E++ + + +L E K I+ LN +EE + M Sbjct: 2010 IMKINYQFTSQISE-------LNELKEEDNKKIYELCQDNSEKKKEIDRLNKEIEEYHNM 2062 Query: 985 NLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVS 1044 N H Q++ + E+ I KLN +K K EI LN ++ S S Sbjct: 2063 N------H-QRENDNEKNLIEK-DEIIQKLNKTIKDKQREIDCLNDQLTEKDES-----S 2109 Query: 1045 DYESKLAQFTT----KLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKL 1100 + KL +F + L + E+E+Q + KQ + + N +L+ L +Q+D K+ E Sbjct: 2110 EENDKLVKFISTLKESLSSKEKEIQNLKKQNEEILKQNNDLKSLNEQQNDD-KQNNEN-- 2166 Query: 1101 TFEMNIPKTEGMIISSTIEPMSDDANN-----VDXXXXXXXXXXXXLKVQEEEEFIQERS 1155 ++ I K E M + + + + + + V K+++E + I +++ Sbjct: 2167 --DIEIMKKEIMKLRTENKDLKNQVSQQHKALVKLAKSLENKNKAEEKLKQELQNISKQN 2224 Query: 1156 VLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLS 1215 +++ + KL +++ K QL+ ELT ++ ++ L + + Sbjct: 2225 IVKNEEDKLTLLVKD---KDNQLQRCRKELTN----ALQKAALYRAGLRSSQKQIIEIKK 2277 Query: 1216 TVAELRSSISS--AVDQRGFEIAELWKQHLAQREADFQKTEHE-LRVQLSAFESKYEQLL 1272 + + +SS+SS + +R + A E + QK E E + ++L+ + + L Sbjct: 2278 EIEDFKSSVSSEDILHERCLFLRARPALLAALTETETQKGEIEAVELELNDTKDSLAKAL 2337 Query: 1273 DSVQ--SSTQEETNKIVTMEQVT--SLQNKLQDKEEHLRNLQEKYADV 1316 + SS E K + + + T +L+ K+++K+ ++EK ++ Sbjct: 2338 KDNRDLSSHIVEMRKTIKLLKKTAITLEEKVKEKDSGREQIEEKVKEL 2385 Score = 145 bits (352), Expect = 8e-33 Identities = 205/925 (22%), Positives = 410/925 (44%), Gaps = 100/925 (10%) Query: 695 TIKDLENDK-EDIMNKLQNYIQENMD--LTD-KLEKMSAEKISELLAKINHEEQSKIQTQ 750 TI D E + K+ + EN D L D +++ + +S A+I+ E+ QTQ Sbjct: 521 TIIDSEESTWNKFVQKIMFILDENFDNLLNDTEIQVNDSALVSIQKARIDELEKKFEQTQ 580 Query: 751 FGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQ 810 ID + +D + ++ E Y+ I E ++ L +K + G + QE Sbjct: 581 QIIDENKELKDT-LNLLQEEFHAYEMTIQSYETTLNEKNQENDKLRQKLESKGIFNQETD 639 Query: 811 KAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKK--NQ--------ILLE 860 K E I+ +L ++ +V +++ ++E+ ++LQ++ NQ +L + Sbjct: 640 KK-DENEIKLKQLNEDYE---NYKKVTNEKIQQLENTKRQLQEQINNQPKPEGNLAMLQK 695 Query: 861 ENQNLQIS---LSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTL 917 EN+ Q L D++ Y L+E+ TD KY ++ +L+ + R + Sbjct: 696 ENEEYQRQINELKDLKTEYLKLIEEKRETD------EKYNKEIEELKDRINR-GEGGDEV 748 Query: 918 IVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMN 977 + + KE ++L E N +++ ++D K +E+ E+ + +LE +L E K E L Sbjct: 749 VEELAKENDELSKE-NEELKEKLKDIKS-SEEIEELTNQIEELEKELNEKK---EQLEQT 803 Query: 978 VEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQV 1037 EL + +E I++ ++ + + E+ NEI +LN +K EEI L +K+ NA+ Sbjct: 804 ENELTQQ-IEEIEEEKSEELKKKNEEIERLQNEIEELNKEIKSLTEEIDDLQEKLENAKK 862 Query: 1038 SYMSMVSDYESKLAQFTTKLENMEEEMQRV---------SKQLLDSKQHNEELQILVREQ 1088 + E ++ ++E+++ +K L++SK+ E+ +L+ ++ Sbjct: 863 EIQELQEYAEKSQENDKQTIDELKEKLRLANETKVTDSDTKVLVESKEAAEQKVLLLEKE 922 Query: 1089 DDQIK-ELKETKLTF-EMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQE 1146 +K E+++ K E N K + I + + + + K+++ Sbjct: 923 ISDLKIEIEDLKSVIDEENEQKVSNTEAENRIHELESEISELKKELDQNNNQQNDEKIEK 982 Query: 1147 EEEFIQE-RSVLQEQSAK--LNTELQECYTKI-IQLETLNTEL-TGHDVVNQEQINQLKS 1201 ++ I++ +SV+ E++ + NTE + ++ ++ L EL ++ N E+I +L+ Sbjct: 983 LQKEIEDLKSVIDEENEQKVSNTEAENRIHELESEISELKKELDQNNNQQNDEKIEKLQK 1042 Query: 1202 KLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQ-HLAQREAD-------FQKT 1253 ++E L E ++ + EL++ +DQ E L Q Q + D +T Sbjct: 1043 EIEDLKNELESSKAENEELQNEFEKEIDQISQEKQNLESQIKYLQEKGDKSEIIDKLNQT 1102 Query: 1254 EHELRVQ---------LSAFESKYEQL---LDSVQSSTQEETNKIVTMEQVT-SLQNKLQ 1300 ELR + + ++S+ E L L +++ S Q K E++ L+NKL+ Sbjct: 1103 IEELRAKVEHMFTQEDIDEYKSEIENLKQELSNIEKSKQISEEKSQDYEEIVHELENKLE 1162 Query: 1301 DKEEHLRNLQEKYADVINQIEILR-------SEIEDEKVAFXXXXXXXXXXXXXXXXDLR 1353 KE L L+ + +IE L+ +E+E EK DL+ Sbjct: 1163 AKETELSKLKSDFEQQTREIETLKENITNLENEMEIEKKNRNSADNEKISHLEKQISDLQ 1222 Query: 1354 TENQ----SYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVN------DAEAKVL 1403 + Q S +M E+ + E A+ +K +N E L Sbjct: 1223 NKLQDKIKSQNEMVEKFKRDFQEMQAKDQKIREEESHASQAKIESLNALLKQSKEENDAL 1282 Query: 1404 ELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILR 1463 ++ H+++L ++I + T + + + E E + QQ K I DL ++ SEL L Sbjct: 1283 KMNHEIKL--NKISEFTKDLEQKVKSKEQEIELLTQQNSVCSKEINDL-HKNNSELKKLS 1339 Query: 1464 LKMHENANHYETMQKESEIERVKLIEELNVKITES--VSLNKQVAELNKAL----EEEVA 1517 ++ N E K + +K ++E +VK T++ +LN +++EL++ + E+E+ Sbjct: 1340 DELQSENNVLEEKLKRL-MSELKFLQETSVKNTDNQITNLNSKISELSEEINILKEKEIK 1398 Query: 1518 KTNEMQTALENQEIEIVTLNDEITN 1542 T E++ + +++ +I+ N+E+ N Sbjct: 1399 LTKEIE-KVTSEKNKIIQDNEEVVN 1422 Score = 59.7 bits (138), Expect = 7e-07 Identities = 86/384 (22%), Positives = 160/384 (41%), Gaps = 33/384 (8%) Query: 1197 NQLKSKLEQLNTEN-DNLLSTVAELRSSISSAVDQRGFEIAELWK-----QHLAQREADF 1250 N+ K+ + EN DNLL+ E++ + S+ V + I EL K Q + + Sbjct: 531 NKFVQKIMFILDENFDNLLNDT-EIQVNDSALVSIQKARIDELEKKFEQTQQIIDENKEL 589 Query: 1251 QKTEHELRVQLSAFE---SKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLR 1307 + T + L+ + A+E YE L+ + K+ + +K + E L+ Sbjct: 590 KDTLNLLQEEFHAYEMTIQSYETTLNEKNQENDKLRQKLESKGIFNQETDKKDENEIKLK 649 Query: 1308 NLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSI 1367 L E Y + ++E+ K L+ EN+ Y Q Q + Sbjct: 650 QLNEDYENYKKVTNEKIQQLENTKRQLQEQINNQPKPEGNLAM-LQKENEEY-QRQINEL 707 Query: 1368 LNINEENAQL----KKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEY 1423 ++ E +L +++ R+N E E+ +L ++ E+ ++ E Sbjct: 708 KDLKTEYLKLIEEKRETDEKYNKEIEELKDRINRGEGGD-EVVEELAKENDELSKENEEL 766 Query: 1424 TITLT--QRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESE 1481 L + ++E E + Q+ E EK + + +KE +L+ EN E Q+ E Sbjct: 767 KEKLKDIKSSEEIEELTNQIEELEKELNE---KKE------QLEQTEN----ELTQQIEE 813 Query: 1482 IERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEIT 1541 IE K EEL K E L ++ ELNK ++ + +++Q LEN + EI L + Sbjct: 814 IEEEKS-EELKKKNEEIERLQNEIEELNKEIKSLTEEIDDLQEKLENAKKEIQELQEYAE 872 Query: 1542 NLQNMVRASSSKIQKHVSFASDTK 1565 Q + + ++++ + A++TK Sbjct: 873 KSQENDKQTIDELKEKLRLANETK 896 >UniRef50_A0CPG2 Cluster: Chromosome undetermined scaffold_23, whole genome shotgun sequence; n=2; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_23, whole genome shotgun sequence - Paramecium tetraurelia Length = 2189 Score = 200 bits (487), Expect = 3e-49 Identities = 298/1479 (20%), Positives = 627/1479 (42%), Gaps = 125/1479 (8%) Query: 151 IKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXX 210 +KEK+ L + Q+K+K E I L+E+I + I + + + Sbjct: 612 LKEKNRDLQLYQLKLKDYEENINSLKEEIERLNSIDKQQQENIYKLEQSHKTKEYQLSKY 671 Query: 211 XEDTKQQMTKMQE----------NFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLL 260 E TK+ K++E FI E +++ + +++ I + + Sbjct: 672 SEQTKEMTNKVKELNEEKTSEIRKFIIQNEELQEQVRIFEIEVKKLQSNIQGNQRTPERT 731 Query: 261 EAARFEISLEHSKLAQELEQXX--XXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEI 318 + E+ + KL Q++ + L +Q I+ E + EI++ + E Sbjct: 732 TKLQQELDDLYDKLNQQIGENADLKIQIQNLSTQIKLKEQEIKKLLEIQLEIQQNSNKE- 790 Query: 319 ANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNT 378 +LTK+I+ L + Q+ K+L++++ + K KK + + S ++ Sbjct: 791 ---NDLTKEIQELHQQINKYEQSIKQLQDQINKLENLIKYKDQQLKKHE--LQQDSWKDN 845 Query: 379 ASKMKSPWSQLSSETLNQ-DTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXX 437 SK+++ +L ++ L + K NK I KLE ++S KE+ I + Sbjct: 846 LSKLENQIEELETQQLRELKQQDKQNKETIKKLENQLKS-------KEHEIKKLQDEIKL 898 Query: 438 XXXXXXGKDTLIAQLQLE---HQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIK 494 + +I Q+ + QQ + L T E EI K++++L + + EI+ Sbjct: 899 QQEKIQSLEQMIEQINDQFHTSQQQLNEVQLKFQLTIREKDFEINKLKQKLGSQKSPEIQ 958 Query: 495 DVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSN 554 + L +++ E +I ++ ++ ++ K++ N++L K+ Q+TI + K + Sbjct: 959 S-EIDSLHQQIIEKETEIIKVREDTSELSQ---KIR-NYELDFKKFQETIKEYQKKLERT 1013 Query: 555 KEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLK 614 ++ L EL + + +++ + N ++ + D+ + KK+ E + E K Sbjct: 1014 TQLEILISEL-KIKDETNQVKIDDQNSTIN--NQDAIIQSKDQTIKKLQEQQR--EFTKK 1068 Query: 615 AISLLESQK--FDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALS 672 L+ QK + Q+LH Q +DK I+ L+ +++ L++QI + Sbjct: 1069 GDQLINVQKKLIETEQQLHEALQNASISQDK---INTLEQQLALKDLELKKLKDQIKEIQ 1125 Query: 673 ASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKI 732 + L ++ +KEQL + +N E++ N+++ QEN +K S E Sbjct: 1126 REVERL----QSKLYEKEQLQQKTIEQQNKIEELENQIEKLKQEN-------KKKSQE-- 1172 Query: 733 SELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRR 792 N + K+Q ++ K +++ IE + L + +I LEE I + ED + Sbjct: 1173 -------NQVLEDKVQQLKKLEEKYKKQQNLIEEHKQTLESLERKIKSLEEQIQINEDEK 1225 Query: 793 YSLERKADQLGSYLQEKQKAYSEYTIQE----DELVNRLAVLMDHDRVVEKQLLEIEHEN 848 YSLER+ D L L++++K + Q+ D+++ +L + +E Q E E Sbjct: 1226 YSLEREVDLLKKKLEDERKQFENKINQQARAKDDIIAKLKEKIAELEKLEAQHFEFTQEV 1285 Query: 849 KEL--QKKNQILLE-----ENQNLQISLSDMQQHYNALVEKANRTDLAESESTK-YQTQL 900 ++L +KK++ +E +N Q + ++Q +L EK +E ES K ++ Sbjct: 1286 EDLKEEKKSRKNIESKLQSDNSIYQKQIKQLEQQIKSLQEKLK----SEEESNKILHNEI 1341 Query: 901 RDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQL 960 + N+K + E LI + +++++ LEI + E + K+ ++E+ I + + Sbjct: 1342 EQINVNIK-VKDE---LIYKLQQQVKKLEISIKEKKEQIKQFKQDISER-SSQISQIDLI 1396 Query: 961 EAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQK------QQTQSPDYTEQYINEINKL 1014 + + +E + I L EE K + + + K Q Q +Q I+ + + Sbjct: 1397 DREKEELNDQI-RLKEKSEESLKQTISTLQSQISKLTKQVQQLIQDKMELQQQIDRLIDI 1455 Query: 1015 NALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDS 1074 +K K+ EI+ L Q I N V + + T K++ +E ++ + + + Sbjct: 1456 ENSIKLKEIEILRLVQ-IENDYQRQKEKVKTLDKTITDQTQKIKIYQEYEKQTKESIKNY 1514 Query: 1075 KQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXX 1134 +Q +E Q ++ + +I +LK+ ++ I K IS E ++ + + Sbjct: 1515 EQELDEKQETIQHLEQEIIKLKQQIDDYQRQITK-----ISKEKETVNQKVKSSETNQQK 1569 Query: 1135 XXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQE 1194 ++++E + + L + L ++L+E + Q + ++ E + Sbjct: 1570 KIDQLE----EQKQELLNDLQTLNIRVEDLQSQLKELQERRDQFQKIDKEKEDIKRTSDT 1625 Query: 1195 QINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQH--LAQREADFQK 1252 + K +++L E L + + + + S ++Q+ + +L +Q+ L Q + Q Sbjct: 1626 SERKYKESIKELEKEIQRLKAEMIKKEHNNSKEIEQQIDKAQKLKQQNTQLEQTIKNLQN 1685 Query: 1253 TEHELRV---QLSAFESKYEQLLDSVQSSTQEETNKIVTM-EQVTSLQNKL----QDKEE 1304 E +L++ Q + + ++ L+ + +I + EQ+ L KL +D+E+ Sbjct: 1686 NEKKLKLLEEQCNQISERSQEKLNKKDQIIDDLNKQIKNLNEQINKLNQKLKSVNKDEED 1745 Query: 1305 HLRNLQEKYADVINQIEILRS-EIEDEK-VAFXXXXXXXXXXXXXXXXDLRTENQSYKQM 1362 + + E ADV + + + E E +K D + Q KQ+ Sbjct: 1746 DIADFGED-ADVDDNNKTKKKYEKESKKDKNEQKTNRQLEKDIEKLTQDNINKTQQIKQL 1804 Query: 1363 QEQSILN---INEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTH-QLELKDSEIYQ 1418 +EQ N I +E + ++ + + + + K ++ Q E++ +E Sbjct: 1805 EEQLKKNQELIQKETIEKQQKTQKEKDENQTIKKQETEIKKKDEQIKKLQEEIQKTEKNS 1864 Query: 1419 KTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHE-NANHYETMQ 1477 K + + E + QQ+ + +++I+ L + +++ + K + N + E + Sbjct: 1865 KEKDNLEQIKVLKQEIDQKTQQITKLQEQIQKL----QKDISASKQKDEKNNKSEQELKK 1920 Query: 1478 KESEIERVK-LIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTL 1536 KE EI ++K IE+ + + E K EL K +EE+ K E ++Q E L Sbjct: 1921 KEEEISKLKEKIEKDSKETNEKKQNEKNQNELIKKQQEEIKKKEEENKKFKDQTNENNKL 1980 Query: 1537 NDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNT 1575 D+++ L+ + KI+K + ++ D+Q T Sbjct: 1981 KDQVSKLEKEKSTTDEKIKKQEDKIKELQKQIDDQKQKT 2019 Score = 174 bits (424), Expect = 1e-41 Identities = 268/1292 (20%), Positives = 566/1292 (43%), Gaps = 129/1292 (9%) Query: 397 DTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQ--- 453 + D +N+ + + + +++L L+ + I T KD LI LQ Sbjct: 238 EKDDHLNQGQNQSVLIEMETLQVQLIQYKIEIEGYKTRMQYIQNELSEKDHLIEDLQNII 297 Query: 454 LEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQIT 513 + + ++ + N Q N+ K N ++ + K+A + Sbjct: 298 KDLTKKIQNRQSNDIQNPISPKNPNKSPSNSFNQNSNNPNK--NQRNPGDATKNAADVFQ 355 Query: 514 QLNDEIDAANKNMIKVKSNHKL---KLKQMQKTIDNFSKVSDSNK-EIVRLTEELHHLSQ 569 Q D D + N K K H L K K+ + +I ++ K+ + K E RL +EL+ Sbjct: 356 QEEDNYDQKDPNEEKKKKKHGLEGAKKKEDEDSIKDYQKIIANLKAENQRLQQELNQAIF 415 Query: 570 KVAELE---EEKGNLQLHLVDYDSGRMIE-SDVYKKMIEMENLAETRLKAISLLESQKFD 625 K+ + E EK N QL L++ + + D K ++E + K + +E + D Sbjct: 416 KINQQEALINEKDN-QLSLLELREKEIRQLKDQLNKQYKLEQENKQLEKKLGEMEQKIQD 474 Query: 626 LVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENL 685 L+ E+ + YD+ ++KL + + QS + K+ L++Q D L A++K++ + + + Sbjct: 475 LMLEI----ENYDQ-DNKLNE--KKQSKKEADYQKA--LQKQKDELLANQKKIEQINKQM 525 Query: 686 KLDKEQLYGTIKDLEND---KEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHE 742 + + +KDL++ K+ + KLQ ++E L LEK + + S+ + K++ E Sbjct: 526 QDEINFFEDQMKDLQDSLRVKDQEVKKLQEQMKE---LNKTLEKSNIQ--SDQIEKLHQE 580 Query: 743 EQSKIQTQFGIDAKIQERDLYIENIESELS--KYKSRICRLEE-SIAVMEDRRYSLERKA 799 S+ Q ++ KIQ+++ I+ E E+ K K+R +L + + E+ SL+ + Sbjct: 581 AHSQTQLLEELEQKIQQQEYEIKTKEQEIKRLKEKNRDLQLYQLKLKDYEENINSLKEEI 640 Query: 800 DQLGSYLQEKQ------------KAY--SEYTIQEDELVNRLAVLMDHDRV-VEKQLLEI 844 ++L S +++Q K Y S+Y+ Q E+ N++ L + + K +++ Sbjct: 641 ERLNSIDKQQQENIYKLEQSHKTKEYQLSKYSEQTKEMTNKVKELNEEKTSEIRKFIIQN 700 Query: 845 EHENKELQ------KKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQ- 897 E ++++ KK Q ++ NQ + +QQ + L +K N+ + E+ K Q Sbjct: 701 EELQEQVRIFEIEVKKLQSNIQGNQRTPERTTKLQQELDDLYDKLNQ-QIGENADLKIQI 759 Query: 898 ----TQLRDLESNLKRITHEHQTLIVQKK-------KEIEDLEIEFNTQIESAIRDKKVL 946 TQ++ E +K++ E Q I Q KEI++L + N + E +I+ + Sbjct: 760 QNLSTQIKLKEQEIKKLL-EIQLEIQQNSNKENDLTKEIQELHQQIN-KYEQSIKQLQDQ 817 Query: 947 NEKYEKNIEYVTQL----EAQLQEYKNNIENLNMNVEELNKMNL-ELIDKHVQKQQT--Q 999 K E I+Y Q E Q +K+N+ L +EEL L EL + Q ++T + Sbjct: 818 INKLENLIKYKDQQLKKHELQQDSWKDNLSKLENQIEELETQQLRELKQQDKQNKETIKK 877 Query: 1000 SPDYTEQYINEINKLNALLKQKDEEIIALNQKI--------------NNAQVSYMSMV-- 1043 + + +EI KL +K + E+I +L Q I N Q+ + + Sbjct: 878 LENQLKSKEHEIKKLQDEIKLQQEKIQSLEQMIEQINDQFHTSQQQLNEVQLKFQLTIRE 937 Query: 1044 SDYE-SKLAQF--TTKLENMEEEMQRVSKQLLDS-------KQHNEELQILVREQDDQIK 1093 D+E +KL Q + K ++ E+ + +Q+++ ++ EL +R + K Sbjct: 938 KDFEINKLKQKLGSQKSPEIQSEIDSLHQQIIEKETEIIKVREDTSELSQKIRNYELDFK 997 Query: 1094 ELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQE 1153 + +ET ++ + +T + I + + D+ N V +Q +++ I++ Sbjct: 998 KFQETIKEYQKKLERTTQLEILISELKIKDETNQVKIDDQNSTINNQDAIIQSKDQTIKK 1057 Query: 1154 RSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNL 1213 Q + K +L K+I+ E E + ++Q++IN L+ +L + E L Sbjct: 1058 LQEQQREFTKKGDQLINVQKKLIETEQQLHEALQNASISQDKINTLEQQLALKDLELKKL 1117 Query: 1214 LSTVAELRSSISSAVDQRGFEIAELWKQHLAQR------EADFQKTEHELR---VQLSAF 1264 + E++ + + + +E +L ++ + Q+ E +K + E + + Sbjct: 1118 KDQIKEIQREV-ERLQSKLYEKEQLQQKTIEQQNKIEELENQIEKLKQENKKKSQENQVL 1176 Query: 1265 ESKYEQLLDSVQSSTQEETNKIVTMEQ-VTSLQNKLQDKEEHLR-NLQEKYADVINQIEI 1322 E K +Q L ++ +++ N I +Q + SL+ K++ EE ++ N EKY+ + ++++ Sbjct: 1177 EDKVQQ-LKKLEEKYKKQQNLIEEHKQTLESLERKIKSLEEQIQINEDEKYS-LEREVDL 1234 Query: 1323 LRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSX 1382 L+ ++EDE+ F L+ + ++++ Q +E LK+ Sbjct: 1235 LKKKLEDERKQFENKINQQARAKDDIIAKLKEKIAELEKLEAQH-FEFTQEVEDLKEEKK 1293 Query: 1383 XXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLV 1442 + + ++ +L Q++ ++ + I ++E E + + Sbjct: 1294 SRKNIESKLQSDNSIYQKQIKQLEQQIKSLQEKLKSEEESNKIL----HNEIEQINVNIK 1349 Query: 1443 EYEKRIEDLTYE-KESELAILRLKMHENANHYETMQKESEIERVKLI----EELNVKITE 1497 ++ I L + K+ E++I K + ++ S+I ++ LI EELN +I Sbjct: 1350 VKDELIYKLQQQVKKLEISIKEKKEQIKQFKQDISERSSQISQIDLIDREKEELNDQIRL 1409 Query: 1498 SVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKH 1557 + + + L+ +++K + L ++E+ D + +++N ++ +I + Sbjct: 1410 KEKSEESLKQTISTLQSQISKLTKQVQQLIQDKMELQQQIDRLIDIENSIKLKEIEILRL 1469 Query: 1558 VSFASDTKQGRDEQLDNTMNKELLDAVPRAEL 1589 V +D + R ++ T++K + D + ++ Sbjct: 1470 VQIENDYQ--RQKEKVKTLDKTITDQTQKIKI 1499 Score = 168 bits (408), Expect = 1e-39 Identities = 235/1214 (19%), Positives = 532/1214 (43%), Gaps = 120/1214 (9%) Query: 149 NTIKEKDNALSVLQVKMKI--METTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXX 206 N+ KE D + ++ +I E +I LQ++IN+ + +I+ K++ Sbjct: 786 NSNKENDLTKEIQELHQQINKYEQSIKQLQDQINKLENLIKYKDQQLKKHELQQDSWKDN 845 Query: 207 XXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFE 266 ++ T+ + + K+ ++L ++SK+ I L++ E Sbjct: 846 LSKLENQIEELETQQLRELKQQDKQNKETIKKLENQLKSKEHEIKKLQD----------E 895 Query: 267 ISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMT-ELT 325 I L+ K+ Q LEQ S ++ E++ K L I E+ Sbjct: 896 IKLQQEKI-QSLEQMIEQ-----------INDQFHTSQQQLNEVQLKFQLTIREKDFEIN 943 Query: 326 K-KIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKS 384 K K +L + +I+ L ++ TE V + + S I RN K Sbjct: 944 KLKQKLGSQKSPEIQSEIDSLHQQIIEKETEIIKVREDTSELSQKI-----RNYELDFKK 998 Query: 385 PWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXG 444 ET+ ++ KK+ + +LE++I L + I ++++ Sbjct: 999 -----FQETI-KEYQKKLERT--TQLEILISELKIKDETNQVKIDDQNSTINNQDAIIQS 1050 Query: 445 KDTLIAQLQLEHQQH-MEGPSLIHVGTNTEDVNEIAKVQEQLKQEL-NDEIKDVNVKDLI 502 KD I +LQ + ++ +G LI+V ++ + ++QL + L N I + L Sbjct: 1051 KDQTIKKLQEQQREFTKKGDQLINV------QKKLIETEQQLHEALQNASISQDKINTLE 1104 Query: 503 EKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTE 562 ++L + ++ +L D+I + + +++S K + QKTI+ +K+ + +I +L + Sbjct: 1105 QQLALKDLELKKLKDQIKEIQREVERLQSKLYEKEQLQQKTIEQQNKIEELENQIEKLKQ 1164 Query: 563 ELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQ 622 E SQ+ LE++ L+ Y + + + + + +E ++ + I + E + Sbjct: 1165 ENKKKSQENQVLEDKVQQLKKLEEKYKKQQNLIEEHKQTLESLERKIKSLEEQIQINEDE 1224 Query: 623 KFDLVQELHILQQKYDEVEDKLADISQLQS---DQVCSEIKSVHLEEQIDALSASKKELA 679 K+ L +E+ +L++K ++ + + Q+ D + +++K E ++ L A E Sbjct: 1225 KYSLEREVDLLKKKLEDERKQFENKINQQARAKDDIIAKLKEKIAE--LEKLEAQHFEFT 1282 Query: 680 LVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKL--EKMSAEKISELLA 737 +E+LK +K+ L++D +++ Q+ L +KL E+ S + + + Sbjct: 1283 QEVEDLKEEKKSRKNIESKLQSDNSIYQKQIKQLEQQIKSLQEKLKSEEESNKILHNEIE 1342 Query: 738 KINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLER 797 +IN + K + + + ++++ ++ I+ + ++ ++K I I+ ++ ++R Sbjct: 1343 QINVNIKVKDELIYKLQQQVKKLEISIKEKKEQIKQFKQDISERSSQISQID----LIDR 1398 Query: 798 KADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQI 857 + ++L ++ K+K+ E+ L ++ L + KQ+ ++ + ELQ++ Sbjct: 1399 EKEELNDQIRLKEKS-------EESLKQTISTLQSQISKLTKQVQQLIQDKMELQQQIDR 1451 Query: 858 LLEENQNLQIS------LSDMQQHYNALVEKANRTDLAESEST-------KYQTQLRDLE 904 L++ ++++ L ++ Y EK D ++ T +Y+ Q ++ Sbjct: 1452 LIDIENSIKLKEIEILRLVQIENDYQRQKEKVKTLDKTITDQTQKIKIYQEYEKQTKESI 1511 Query: 905 SNLKRITHEHQTLIVQKKKEIEDLE---IEFNTQIESAIRDKKVLNEKYEKN----IEYV 957 N ++ E Q I ++EI L+ ++ QI ++K+ +N+K + + + + Sbjct: 1512 KNYEQELDEKQETIQHLEQEIIKLKQQIDDYQRQITKISKEKETVNQKVKSSETNQQKKI 1571 Query: 958 TQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNAL 1017 QLE Q QE N+++ LN+ VE+L EL ++ + Q Q D ++ I + + Sbjct: 1572 DQLEEQKQELLNDLQTLNIRVEDLQSQLKELQER---RDQFQKIDKEKEDIKRTSDTSE- 1627 Query: 1018 LKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQH 1077 ++ E I L ++I + + + ++ Q K + ++++ ++ +Q + + Q+ Sbjct: 1628 -RKYKESIKELEKEIQRLKAEMIKKEHNNSKEIEQQIDKAQKLKQQNTQL-EQTIKNLQN 1685 Query: 1078 NEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXX 1137 NE+ L+ EQ +QI E + KL + I ++ I+ +++ N ++ Sbjct: 1686 NEKKLKLLEEQCNQISERSQEKLNKKDQIIDD----LNKQIKNLNEQINKLNQKLKSVN- 1740 Query: 1138 XXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQIN 1197 ++EE+ I + ++ N + ++ Y K + D Q+ Sbjct: 1741 -------KDEEDDIADFG--EDADVDDNNKTKKKYEK----------ESKKDKNEQKTNR 1781 Query: 1198 QLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHEL 1257 QL+ +E+L +N N + +L + +Q + + KQ Q+E D +T + Sbjct: 1782 QLEKDIEKLTQDNINKTQQIKQLEEQLKK--NQELIQKETIEKQQKTQKEKDENQTIKKQ 1839 Query: 1258 RVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVI 1317 ++ + + ++L + +Q T++ + + +EQ+ L+ ++ K + + LQE+ + Sbjct: 1840 ETEIKKKDEQIKKLQEEIQ-KTEKNSKEKDNLEQIKVLKQEIDQKTQQITKLQEQIQKL- 1897 Query: 1318 NQIEILRSEIEDEK 1331 Q +I S+ +DEK Sbjct: 1898 -QKDISASKQKDEK 1910 Score = 162 bits (394), Expect = 6e-38 Identities = 255/1148 (22%), Positives = 512/1148 (44%), Gaps = 123/1148 (10%) Query: 477 EIAKVQEQLKQELN---DEIKDVN----VKDLIEKLKSAEEQITQLNDEIDAANKNMIKV 529 +I ++ +Q++ E+N D++KD+ VKD +++K +EQ+ +LN ++ +N ++ Sbjct: 517 KIEQINKQMQDEINFFEDQMKDLQDSLRVKD--QEVKKLQEQMKELNKTLEKSNIQSDQI 574 Query: 530 KSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYD 589 + H+ Q Q + K+ EI +E+ L +K +L+ QL L DY+ Sbjct: 575 EKLHQEAHSQTQLLEELEQKIQQQEYEIKTKEQEIKRLKEKNRDLQL----YQLKLKDYE 630 Query: 590 SGRMIESDVYKKMIE-MENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADIS 648 I S K+ IE + ++ + + + I LE +L ++ E+ +K+ +++ Sbjct: 631 EN--INS--LKEEIERLNSIDKQQQENIYKLEQSHKTKEYQLSKYSEQTKEMTNKVKELN 686 Query: 649 QLQSDQVCSEI-KSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIM 707 + ++ ++ I ++ L+EQ+ K+L I+ + E+ T K L+ + +D+ Sbjct: 687 EEKTSEIRKFIIQNEELQEQVRIFEIEVKKLQSNIQGNQRTPER---TTK-LQQELDDLY 742 Query: 708 NKLQNYIQENMDLTDKLEKMSAE-KISEL----LAKINHEEQSKIQTQFGIDAKIQERDL 762 +KL I EN DL +++ +S + K+ E L +I E Q + + +IQE Sbjct: 743 DKLNQQIGENADLKIQIQNLSTQIKLKEQEIKKLLEIQLEIQQNSNKENDLTKEIQELHQ 802 Query: 763 YIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQE-D 821 I E + + + +I +LE I + + E + D L + + E Q+ Sbjct: 803 QINKYEQSIKQLQDQINKLENLIKYKDQQLKKHELQQDSWKDNLSKLENQIEELETQQLR 862 Query: 822 ELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVE 881 EL + + + +E QL EHE K+LQ + ++ E+ Q+L+ + + ++ + Sbjct: 863 ELKQQDKQNKETIKKLENQLKSKEHEIKKLQDEIKLQQEKIQSLEQMIEQINDQFHTSQQ 922 Query: 882 KANRTDLA--------ESESTKYQTQLRDLESN--LKRITHEHQTLIVQKKKEI----ED 927 + N L + E K + +L +S I HQ I++K+ EI ED Sbjct: 923 QLNEVQLKFQLTIREKDFEINKLKQKLGSQKSPEIQSEIDSLHQQ-IIEKETEIIKVRED 981 Query: 928 LEIEFNTQIESAIRDKKVLNE---KYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKM 984 E + +I + D K E +Y+K +E TQLE + E K E + +++ N Sbjct: 982 TS-ELSQKIRNYELDFKKFQETIKEYQKKLERTTQLEILISELKIKDETNQVKIDDQNST 1040 Query: 985 --NLELI----DKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVS 1038 N + I D+ ++K Q Q ++T++ IN L++ + + L++ + NA +S Sbjct: 1041 INNQDAIIQSKDQTIKKLQEQQREFTKKGDQLINVQKKLIETEQQ----LHEALQNASIS 1096 Query: 1039 YMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKET 1098 ++ E +LA +L+ ++++++ + +++ E LQ + E++ +L++ Sbjct: 1097 -QDKINTLEQQLALKDLELKKLKDQIKEIQREV-------ERLQSKLYEKE----QLQQK 1144 Query: 1099 KLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQ 1158 + + I + E I E + + LK + EE++ +++++++ Sbjct: 1145 TIEQQNKIEELENQI-----EKLKQENKKKSQENQVLEDKVQQLK-KLEEKYKKQQNLIE 1198 Query: 1159 EQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVA 1218 E L E E K ++ + E + + + +++ LK KLE + +N ++ A Sbjct: 1199 EHKQTL--ESLERKIKSLEEQIQINEDEKYSL--EREVDLLKKKLEDERKQFENKINQQA 1254 Query: 1219 ELRSSISSAVDQRGFEIAELWKQHLA-QREADFQKTEHELRVQLSAFESKYEQLLDSVQS 1277 + I + + ++ E+ +L QH +E + K E + R + ESK L S S Sbjct: 1255 RAKDDIIAKLKEKIAELEKLEAQHFEFTQEVEDLKEEKKSRKNI---ESK----LQSDNS 1307 Query: 1278 STQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXX 1337 Q++ ++ +Q+ SLQ KL+ +EE + L + I QI + +++DE + Sbjct: 1308 IYQKQIKQLE--QQIKSLQEKLKSEEESNKILHNE----IEQINV-NIKVKDELI----- 1355 Query: 1338 XXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVND 1397 ++ + + KQ ++ +I+E ++Q+ + ++ Sbjct: 1356 -YKLQQQVKKLEISIKEKKEQIKQFKQ----DISERSSQISQIDLIDREKEELND-QIRL 1409 Query: 1398 AEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKES 1457 E L + S+I + T + L Q E + +L++ E I K Sbjct: 1410 KEKSEESLKQTISTLQSQISKLTKQVQ-QLIQDKMELQQQIDRLIDIENSI------KLK 1462 Query: 1458 ELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVA 1517 E+ ILRL EN Y+ QKE K I + KI KQ E K E+E+ Sbjct: 1463 EIEILRLVQIEN--DYQR-QKEKVKTLDKTITDQTQKIKIYQEYEKQTKESIKNYEQEL- 1518 Query: 1518 KTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSK---IQKHVSFASDTKQGRDEQLDN 1574 +E Q +++ E EI+ L +I + Q + S + + + V + +Q + +QL+ Sbjct: 1519 --DEKQETIQHLEQEIIKLKQQIDDYQRQITKISKEKETVNQKVKSSETNQQKKIDQLEE 1576 Query: 1575 TMNKELLD 1582 +ELL+ Sbjct: 1577 -QKQELLN 1583 Score = 153 bits (370), Expect = 5e-35 Identities = 211/1075 (19%), Positives = 472/1075 (43%), Gaps = 74/1075 (6%) Query: 158 LSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQ 217 +S L++K + + I D IN +D II++K++ K+ Sbjct: 1020 ISELKIKDETNQVKIDDQNSTINNQDAIIQSKDQTIKKLQEQQREFTKKGDQLINVQKKL 1079 Query: 218 MTKMQENFIAME--AEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLA 275 + Q+ A++ + +D+ L + + KD+ + L++ K ++ E+ SKL Sbjct: 1080 IETEQQLHEALQNASISQDKINTLEQQLALKDLELKKLKDQIKEIQR---EVERLQSKL- 1135 Query: 276 QELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLE--IANMTELTKKIELLEH 333 E EQ L Q + E K + +E LE + + +L +K + ++ Sbjct: 1136 YEKEQLQQKTIEQQNKIEELENQIEKLKQENKKKSQENQVLEDKVQQLKKLEEKYKKQQN 1195 Query: 334 LNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSET 393 L + +QT + LE K+ ++ E ++ K + + K ++++ + Sbjct: 1196 LIEEHKQTLESLERKIKSL-EEQIQINEDEKYSLEREVDLLKKKLEDERKQFENKINQQA 1254 Query: 394 LNQDTDKKINKNEIAKLEMV----------IQSLNKDLVDKEYVISEKDTXXXXXXXXXX 443 +D K +IA+LE + ++ L ++ ++ + S+ + Sbjct: 1255 RAKDDIIAKLKEKIAELEKLEAQHFEFTQEVEDLKEEKKSRKNIESKLQSDNSIYQKQIK 1314 Query: 444 GKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIK--DVNVKDL 501 + I LQ + + E ++H E +N KV+++L +L ++K ++++K+ Sbjct: 1315 QLEQQIKSLQEKLKSEEESNKILH--NEIEQINVNIKVKDELIYKLQQQVKKLEISIKEK 1372 Query: 502 IEKLKSAEEQITQLNDEIDAANK-NMIKVKSNHKLKLKQMQKTIDNFSK-VSDSNKEIVR 559 E++K ++ I++ + +I + + K + N +++LK+ K+ ++ + +S +I + Sbjct: 1373 KEQIKQFKQDISERSSQISQIDLIDREKEELNDQIRLKE--KSEESLKQTISTLQSQISK 1430 Query: 560 LTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLL 619 LT+++ L Q EL+++ L +D ++ ++ +++++EN + + + + L Sbjct: 1431 LTKQVQQLIQDKMELQQQIDRL----IDIENSIKLKEIEILRLVQIENDYQRQKEKVKTL 1486 Query: 620 ESQKFDLVQELHILQQKYDEVEDKLADISQ-LQSDQVCS---EIKSVHLEEQID----AL 671 + D Q++ I Q+ + ++ + + Q L Q E + + L++QID + Sbjct: 1487 DKTITDQTQKIKIYQEYEKQTKESIKNYEQELDEKQETIQHLEQEIIKLKQQIDDYQRQI 1546 Query: 672 SASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEK 731 + KE V + +K + I LE K++++N LQ DL +L+++ + Sbjct: 1547 TKISKEKETVNQKVKSSETNQQKKIDQLEEQKQELLNDLQTLNIRVEDLQSQLKELQERR 1606 Query: 732 ISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEES----IAV 787 + KI+ E++ +T + K +E I+ +E E+ + K+ + + E + I Sbjct: 1607 --DQFQKIDKEKEDIKRTSDTSERKYKES---IKELEKEIQRLKAEMIKKEHNNSKEIEQ 1661 Query: 788 MEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAV-----LMDHDRVVEKQLL 842 D+ L+++ QL ++ Q + + E++ N+++ L D++++ Sbjct: 1662 QIDKAQKLKQQNTQLEQTIKNLQNNEKKLKLLEEQC-NQISERSQEKLNKKDQIIDDLNK 1720 Query: 843 EIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLA-ESESTKYQTQL- 900 +I++ N+++ K NQ L N++ + ++D + +A V+ N+T E ES K + + Sbjct: 1721 QIKNLNEQINKLNQKLKSVNKDEEDDIADFGE--DADVDDNNKTKKKYEKESKKDKNEQK 1778 Query: 901 --RDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNT-QIESAIRDKKVLNEKYE-----K 952 R LE +++++T ++ Q K+ E L+ Q E+ + +K EK E K Sbjct: 1779 TNRQLEKDIEKLTQDNINKTQQIKQLEEQLKKNQELIQKETIEKQQKTQKEKDENQTIKK 1838 Query: 953 NIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEIN 1012 + + + Q+++ + I+ N +E + + + K Q+TQ ++ I ++ Sbjct: 1839 QETEIKKKDEQIKKLQEEIQKTEKNSKEKDNLEQIKVLKQEIDQKTQQITKLQEQIQKLQ 1898 Query: 1013 KLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLL 1072 K + KQKDE+ Q++ + + E + K +N + + + + KQ Sbjct: 1899 KDISASKQKDEKNNKSEQELKKKEEEISKLKEKIEKDSKETNEKKQNEKNQNELIKKQQE 1958 Query: 1073 DSKQHNEELQILVREQD------DQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDAN 1126 + K+ EE + + + DQ+ +L++ K T + I K E I ++ DD Sbjct: 1959 EIKKKEEENKKFKDQTNENNKLKDQVSKLEKEKSTTDEKIKKQEDKI--KELQKQIDDQK 2016 Query: 1127 NVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETL 1181 + ++ Q + +E KL ++ E II LE+L Sbjct: 2017 QKTPTNNRDDPNDKQGQSDKKPGPYQNDTKYKELVIKLEKQIDELKIHIIYLESL 2071 Score = 151 bits (365), Expect = 2e-34 Identities = 237/1148 (20%), Positives = 493/1148 (42%), Gaps = 103/1148 (8%) Query: 471 NTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVK 530 N+ + ++ + +QL QEL+ K + +D + EE + + + EI+ + +I++ Sbjct: 135 NSNKLKQLEEQNQQLIQELDLITKRLLDRDNAQGTVDYEELLRERDQEIEILTQQIIQIS 194 Query: 531 SNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDS 590 +N K + F SD ++TE + Q + EL+E+ L++ +++ D Sbjct: 195 NN---------KQVKQFDPSSDKR----QITETEEYYGQIIKELQEKIEQLRIIIIEKDD 241 Query: 591 GRMIESDVYKKMIEMENLAETRLKAISLLESQKF-------DLVQELHILQQKYDEVEDK 643 + + +IEME L ++ +E K +L ++ H+++ + ++D Sbjct: 242 -HLNQGQNQSVLIEMETLQVQLIQYKIEIEGYKTRMQYIQNELSEKDHLIEDLQNIIKDL 300 Query: 644 LADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDK 703 I QS+ + + I + + + D + + E D Sbjct: 301 TKKIQNRQSNDIQNPISPKNPNKSPSNSFNQNSNNPNKNQRNPGDATKNAADVFQQEEDN 360 Query: 704 EDIMNKLQNYIQENMDLTDKLEKMSAEKISE---LLAKINHEEQSKIQTQFGIDAKIQER 760 D + + ++ L +K + I + ++A + E Q Q KI ++ Sbjct: 361 YDQKDPNEEKKKKKHGLEGAKKKEDEDSIKDYQKIIANLKAENQRLQQELNQAIFKINQQ 420 Query: 761 DLYIENIESELSKYKSRICRLEESIAVMED---RRYSLERKADQLGSYLQEKQKAYSEYT 817 + I +++LS + R E+ I ++D ++Y LE++ QL L E ++ + Sbjct: 421 EALINEKDNQLSLLELR----EKEIRQLKDQLNKQYKLEQENKQLEKKLGEMEQKIQDLM 476 Query: 818 IQ-----EDELVN---RLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISL 869 ++ +D +N + D+ + ++KQ E+ K++++ N+ + +E + + Sbjct: 477 LEIENYDQDNKLNEKKQSKKEADYQKALQKQKDELLANQKKIEQINKQMQDEINFFEDQM 536 Query: 870 SDMQQHYNALVEKANR--TDLAESESTKYQTQLR-DLESNLKRITHEHQTLIVQKKKEIE 926 D+Q ++ + + E T ++ ++ D L + H L+ + +++I+ Sbjct: 537 KDLQDSLRVKDQEVKKLQEQMKELNKTLEKSNIQSDQIEKLHQEAHSQTQLLEELEQKIQ 596 Query: 927 DLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNL 986 E E T+ E I+ K N + + E + K IE LN ++++ + N+ Sbjct: 597 QQEYEIKTK-EQEIKRLKEKNRDLQLYQLKLKDYEENINSLKEEIERLN-SIDKQQQENI 654 Query: 987 ELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEI---IALNQKINNA----QVSY 1039 +++ + ++ Q Y+EQ NK+ L ++K EI I N+++ ++ Sbjct: 655 YKLEQSHKTKEYQLSKYSEQTKEMTNKVKELNEEKTSEIRKFIIQNEELQEQVRIFEIEV 714 Query: 1040 MSMVSDYE--SKLAQFTTKL-ENMEEEMQRVSKQL---LDSKQHNEELQILVREQDDQIK 1093 + S+ + + + TTKL + +++ ++++Q+ D K + L ++ ++ +IK Sbjct: 715 KKLQSNIQGNQRTPERTTKLQQELDDLYDKLNQQIGENADLKIQIQNLSTQIKLKEQEIK 774 Query: 1094 ELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLK--VQEEEEFI 1151 +L E +L + N K ++ I+ + N + L+ ++ +++ + Sbjct: 775 KLLEIQLEIQQNSNKEND--LTKEIQELHQQINKYEQSIKQLQDQINKLENLIKYKDQQL 832 Query: 1152 QERSVLQEQSAKLNTELQECYTKIIQLETLN-TELTGHDVVNQEQI----NQLKSKLEQL 1206 ++ LQ+ S K N L + +I +LET EL D N+E I NQLKSK ++ Sbjct: 833 KKHE-LQQDSWKDN--LSKLENQIEELETQQLRELKQQDKQNKETIKKLENQLKSKEHEI 889 Query: 1207 NTENDNL---LSTVAELRSSISSAVDQRGFEIAEL----WKQHLAQREADFQKTEHELRV 1259 D + + L I DQ +L K L RE DF+ ++L+ Sbjct: 890 KKLQDEIKLQQEKIQSLEQMIEQINDQFHTSQQQLNEVQLKFQLTIREKDFE--INKLKQ 947 Query: 1260 QLSAFES-KYEQLLDSV-QSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQE------ 1311 +L + +S + + +DS+ Q ++ET I E + L K+++ E + QE Sbjct: 948 KLGSQKSPEIQSEIDSLHQQIIEKETEIIKVREDTSELSQKIRNYELDFKKFQETIKEYQ 1007 Query: 1312 KYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQ--SILN 1369 K + Q+EIL SE++ + +++++Q+ K++QEQ Sbjct: 1008 KKLERTTQLEILISELKIKDETNQVKIDDQNSTINNQDAIIQSKDQTIKKLQEQQREFTK 1067 Query: 1370 INEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQ 1429 ++ ++K + ++ K+ L QL LKD E+ K + I Q Sbjct: 1068 KGDQLINVQKKLIETEQQLHEALQNASISQDKINTLEQQLALKDLEL--KKLKDQIKEIQ 1125 Query: 1430 RNDEFENVRQQLVEYE----KRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERV 1485 R E E ++ +L E E K IE +E E I +LK E E +++++ Sbjct: 1126 R--EVERLQSKLYEKEQLQQKTIEQQNKIEELENQIEKLKQENKKKSQENQVLEDKVQQL 1183 Query: 1486 KLIEELNVKITESVSLNKQVAE----LNKALEEEVAKTNEMQTALENQEIEIV--TLNDE 1539 K +EE K + +KQ E K+LEE++ + + +LE +E++++ L DE Sbjct: 1184 KKLEEKYKKQQNLIEEHKQTLESLERKIKSLEEQIQINEDEKYSLE-REVDLLKKKLEDE 1242 Query: 1540 ITNLQNMV 1547 +N + Sbjct: 1243 RKQFENKI 1250 Score = 85.8 bits (203), Expect = 9e-15 Identities = 178/937 (18%), Positives = 393/937 (41%), Gaps = 51/937 (5%) Query: 658 EIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQEN 717 EIK L D L+A +E E LK + + LY KDL ++ ++L+ I+ N Sbjct: 22 EIKIKQLLRANDKLNAVVRETLAENEQLKGNIDVLYKENKDLNRLNIELCDQLER-IKRN 80 Query: 718 M---DLTDKLEKMSAEKISE--LLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELS 772 DK ++I++ LL + +E + + ++ D +I+ + ++L Sbjct: 81 TRQHSTHDKTIIDYEQEITQLKLLLQEKQKEVNSFKIRYNEDLQIKLDIVDKSGNSNKLK 140 Query: 773 KYKSRICRLEESIAVMEDRRYSLERKADQLG--SYLQEKQKAYSEYTIQEDELVNRLAVL 830 + + + +L + + ++ R + + L+E+ + T Q ++ N V Sbjct: 141 QLEEQNQQLIQELDLITKRLLDRDNAQGTVDYEELLRERDQEIEILTQQIIQISNNKQVK 200 Query: 831 MDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAE 890 ++Q+ E E ++ K+ L E+ + L+I + + H N + N++ L E Sbjct: 201 QFDPSSDKRQITETEEYYGQIIKE---LQEKIEQLRIIIIEKDDHLN---QGQNQSVLIE 254 Query: 891 SESTKYQTQLRDLE-SNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEK 949 E+ + Q +E K Q + +K IEDL+ + I++++ + Sbjct: 255 METLQVQLIQYKIEIEGYKTRMQYIQNELSEKDHLIEDLQ-NIIKDLTKKIQNRQ--SND 311 Query: 950 YEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQT-QSPDYTEQYI 1008 + I ++ + N N N N D Q++ D E+ Sbjct: 312 IQNPISPKNPNKSPSNSFNQNSNNPNKNQRNPGDATKNAADVFQQEEDNYDQKDPNEEKK 371 Query: 1009 NEINKLNALLKQKDEEIIALNQK-INNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRV 1067 + + L K++DE+ I QK I N + + + +L Q K+ E + Sbjct: 372 KKKHGLEGAKKKEDEDSIKDYQKIIANLKAENQRL----QQELNQAIFKINQQEALINEK 427 Query: 1068 SKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANN 1127 QL + +E++ L + + Q K +E K E + + E I +E + D +N Sbjct: 428 DNQLSLLELREKEIRQLKDQLNKQYKLEQENK-QLEKKLGEMEQKIQDLMLEIENYDQDN 486 Query: 1128 VDXXXXXXXXXXXXLKV--QEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTEL 1185 K ++++E + + +++ + ++ E+ ++ L+ + + Sbjct: 487 KLNEKKQSKKEADYQKALQKQKDELLANQKKIEQINKQMQDEINFFEDQMKDLQD-SLRV 545 Query: 1186 TGHDVVN-QEQINQLKSKLEQLNTENDNL--LSTVAELRSSISSAVDQRGFEIAELWKQH 1242 +V QEQ+ +L LE+ N ++D + L A ++ + ++Q+ + + Sbjct: 546 KDQEVKKLQEQMKELNKTLEKSNIQSDQIEKLHQEAHSQTQLLEELEQK----IQQQEYE 601 Query: 1243 LAQREADFQKTEHELR-VQLSAFESK-YEQLLDSVQSSTQEETNKIVTMEQ--VTSLQNK 1298 + +E + ++ + + R +QL + K YE+ ++S++ E N I +Q + L+ Sbjct: 602 IKTKEQEIKRLKEKNRDLQLYQLKLKDYEENINSLKEEI-ERLNSIDKQQQENIYKLEQS 660 Query: 1299 LQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQS 1358 + KE L E+ ++ N+++ L E E F +++ + QS Sbjct: 661 HKTKEYQLSKYSEQTKEMTNKVKELNEEKTSEIRKFIIQNEELQEQVRIFEIEVK-KLQS 719 Query: 1359 YKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQ 1418 Q +++ E +L++ D + ++ L+ Q++LK+ EI + Sbjct: 720 NIQGNQRT----PERTTKLQQELDDLYDKLNQQIGENADLKIQIQNLSTQIKLKEQEI-K 774 Query: 1419 KTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQ- 1477 K E + + Q +++ ++ +++ E ++I YE+ + ++ EN Y+ Q Sbjct: 775 KLLEIQLEIQQNSNKENDLTKEIQELHQQIN--KYEQSIKQLQDQINKLENLIKYKDQQL 832 Query: 1478 KESEIERVKLIEELNVKITESVSL-NKQVAELNKALEEEVAKTNEMQTALENQEIEIVTL 1536 K+ E+++ + L+ + L +Q+ EL + ++ +++ L+++E EI L Sbjct: 833 KKHELQQDSWKDNLSKLENQIEELETQQLRELKQQDKQNKETIKKLENQLKSKEHEIKKL 892 Query: 1537 NDEITNLQNMVRASSSKIQK-HVSFASDTKQGRDEQL 1572 DEI Q +++ I++ + F + +Q + QL Sbjct: 893 QDEIKLQQEKIQSLEQMIEQINDQFHTSQQQLNEVQL 929 Score = 79.0 bits (186), Expect = 1e-12 Identities = 121/636 (19%), Positives = 268/636 (42%), Gaps = 48/636 (7%) Query: 930 IEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELI 989 + +Q + I+ K++L + N V + A+ ++ K NI+ L ++LN++N+EL Sbjct: 13 LSHQSQDDYEIKIKQLLRANDKLNA-VVRETLAENEQLKGNIDVLYKENKDLNRLNIELC 71 Query: 990 D--KHVQKQQTQSPDYTE---QYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMV- 1043 D + +++ Q + + Y EI +L LL++K +E+ + + N + +V Sbjct: 72 DQLERIKRNTRQHSTHDKTIIDYEQEITQLKLLLQEKQKEVNSFKIRYNEDLQIKLDIVD 131 Query: 1044 -SDYESKLAQFTTKLENMEEEMQRVSKQLL--DSKQHNEELQILVREQDDQIKELKETKL 1100 S +KL Q + + + +E+ ++K+LL D+ Q + + L+RE+D +I+ L + + Sbjct: 132 KSGNSNKLKQLEEQNQQLIQELDLITKRLLDRDNAQGTVDYEELLRERDQEIEILTQQII 191 Query: 1101 TFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQ 1160 N + +P SD + ++QE+ E Q R ++ E+ Sbjct: 192 QISNNKQVKQ-------FDPSSDKRQITETEEYYGQIIK---ELQEKIE--QLRIIIIEK 239 Query: 1161 SAKLN-----TELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLS 1215 LN + L E T +QL E+ G+ Q N+L K + L + N++ Sbjct: 240 DDHLNQGQNQSVLIEMETLQVQLIQYKIEIEGYKTRMQYIQNELSEK-DHLIEDLQNIIK 298 Query: 1216 TVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSV 1275 + + + S Q K + R A ++ + Sbjct: 299 DLTKKIQNRQSNDIQNPISPKNPNKSPSNSFNQNSNNPNKNQRNPGDATKNAADVFQQEE 358 Query: 1276 QSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFX 1335 + Q++ N+ ++ K ++ E+ +++ Q+ A++ + + L+ E+ ++ + Sbjct: 359 DNYDQKDPNEEKKKKKHGLEGAKKKEDEDSIKDYQKIIANLKAENQRLQQEL-NQAIFKI 417 Query: 1336 XXXXXXXXXXXXXXXDLRTENQSYKQMQEQ--SILNINEENAQLKKSSXXXXXXXXXXXX 1393 L + +Q+++Q + +EN QL+K Sbjct: 418 NQQEALINEKDNQLSLLELREKEIRQLKDQLNKQYKLEQENKQLEKK-------LGEMEQ 470 Query: 1394 RVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTY 1453 ++ D ++ +L + + +K +Y L ++ DE L+ +K+IE + Sbjct: 471 KIQDLMLEIENYDQDNKLNEKKQSKKEADYQKALQKQKDE-------LLANQKKIEQINK 523 Query: 1454 EKESELAILRLKMHENANHYETMQKESEIERV-KLIEELNVKITESVSLNKQVAELNKAL 1512 + + E+ +M + + K+ E++++ + ++ELN + +S + Q+ +L++ Sbjct: 524 QMQDEINFFEDQMKDLQDSLRV--KDQEVKKLQEQMKELNKTLEKSNIQSDQIEKLHQEA 581 Query: 1513 EEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVR 1548 + E++ ++ QE EI T EI L+ R Sbjct: 582 HSQTQLLEELEQKIQQQEYEIKTKEQEIKRLKEKNR 617 >UniRef50_UPI00015B5D72 Cluster: PREDICTED: similar to viral A-type inclusion protein, putative; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to viral A-type inclusion protein, putative - Nasonia vitripennis Length = 3263 Score = 197 bits (481), Expect = 2e-48 Identities = 302/1431 (21%), Positives = 609/1431 (42%), Gaps = 162/1431 (11%) Query: 212 EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271 +D ++T++ +EA D L ++++ KD I S +A L+ A ++S++ Sbjct: 186 QDKDNKITELSNKIFELEAVIID----LQENLKEKDSVIDSKTKAITLMSA---DLSMKG 238 Query: 272 SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELL 331 LE L + S++ E+ +EE + E K+ E + Sbjct: 239 KTTLDTLEDTKDEMRSMQENFV-LVESSLKKKAEQIATLEENVQ-SLTEKLEAQKQAETV 296 Query: 332 E-HLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLS 390 + T + ++ + +M + + K + + ++ +S L+ Sbjct: 297 SADFSRSTMDTLADTKDAMKSMQENFVLIETSLKSKNEHLLKQLEEREIKLAESEARILN 356 Query: 391 SETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVIS-------EKDTXXXXXXXXXX 443 ET +++ N EI ++ +N+ L D++Y + +K Sbjct: 357 LET-GLGIERQPNVEEITYKVDKLEEMNRKLQDEKYELQKNIAELQDKIISTESRTDESI 415 Query: 444 GKDTLIAQLQL------EHQQHMEGPSLIHVGTNTEDVNE--------IAKVQEQLKQEL 489 +D IA+L+ + QH+E + ++NE I ++++Q+ Sbjct: 416 MEDNRIAELESLIEELKKSNQHLEEEYKAALHNQVAEMNERNETLSNKIVELEKQVNDVT 475 Query: 490 NDEIKDVNVKDLIE-KLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFS 548 ND+I+ + IE + +EQ+ +L E++ NK+MIK+K+ HK KLK +QK ++NF Sbjct: 476 NDKIELESKLSAIETEAPKEDEQVQKLTKELEELNKSMIKLKAQHKNKLKNLQKQLENFK 535 Query: 549 KVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENL 608 KVSD N E+V+ L +VA LEEEKGNLQL LVD+D + D +++ ++E Sbjct: 536 KVSDKNAELVK-------LGNQVALLEEEKGNLQLSLVDFDELKASAGDWKERIADLEGK 588 Query: 609 A-------ETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKS 661 ET ++AI++LE+QK DL+QELH ++Q+ +E + A+ L +V +E+K Sbjct: 589 VASQAKEIETHIEAIAILENQKLDLMQELHAVKQEVSSLEAENAESENL---RVTAEMKV 645 Query: 662 VHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLT 721 V LEE+I++ L K+Q + D E + + +++N QEN L+ Sbjct: 646 VDLEEEIES----------------LHKQQQAEPLTDAE--RIEFQRQIENLTQENERLS 687 Query: 722 DKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRL 781 K+ K+ K S + +S ++T +D+ + +++L + + R Sbjct: 688 QKVSKLEELKSSSEVG----STESFVKTGSNVDSTESFEAFAADADKADLLRKIDGLTR- 742 Query: 782 EESIAVMEDRRYSLERKADQLGSYLQ-EKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQ 840 E+ A++E E+ + GS E+ + E T + + L +++ VV+ Sbjct: 743 -ENGALLEKLTRFEEKGSSDTGSTESFERIPEHGESTSRLENLTRE-----NYELVVKLT 796 Query: 841 LLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQL 900 LE + E K Q +L+EN+ L L +++ NA+VE+ R E S + + Sbjct: 797 KLEEKLAASEADTKLQEVLQENERLVAKLKQLEE--NAVVEEVVR----EKRSVEVEEVP 850 Query: 901 RDLESNLKRITHEHQT-LIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQ 959 R E ++ + E T ++V+ + + E +IE + + + E + Sbjct: 851 RTQEPEIEETSSEAPTEVLVESTESPPHIVDELVAKIEELKSSLEAIGREKE-------E 903 Query: 960 LEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLK 1019 L A+L+E + + L + E + ++ Q Q P E K +A+ Sbjct: 904 LAAKLKEKEPVAQELQVE-ETIVPAEASVVKSSAQ----QDPSEAEL------KSDAV-- 950 Query: 1020 QKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNE 1079 + E I AL ++I +++++ ++ + TKL + EEE++R S QL S+ H++ Sbjct: 951 -QSEAIAALEREIERC----TALIAEQKAVIEDLKTKLADKEEELERKSAQLASSESHDQ 1005 Query: 1080 ---ELQILVREQDDQIKELKETK-----LTFEMNIPKTEGMIISSTIEPMSDDANNVDXX 1131 + +L RE ++ E+ E K + +M + + I + + + N+ Sbjct: 1006 DQLDAHVLRRELEESASEIAEWKHKCAEMEEKMKVLEKGRQHIEEGFQALQTENKNLLEQ 1065 Query: 1132 XXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVV 1191 LK +E + I + E ++ E+ +++ E L + D+ Sbjct: 1066 SEHKDVMLSQLK-EELDHTISD----FEAKSRAQGEVIASQEQLV--EELRKNVEEKDLE 1118 Query: 1192 NQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQ 1251 Q + +QL++ L +++ D L + + + V QR IA L + + + Sbjct: 1119 LQGKYSQLQNDLIKMDELQDKL--------ARLEAQVQQRDATIASL-TEEVETLRTNAS 1169 Query: 1252 KTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQ-------VTSLQNKLQDKEE 1304 E +L + +E+L D S + EE N++ MEQ V L+ KL K Sbjct: 1170 VVEEDLFMARHQLTDLHEKLKD---SKSLEEYNQL--MEQLNDKTMLVEELETKLSQKLA 1224 Query: 1305 HLRNLQEKYADVINQIEILRS--EIEDEKVA----FXXXXXXXXXXXXXXXXDLRTENQS 1358 + L+ + ++++ LR ++++ ++A D+ Sbjct: 1225 EVNALKAQVESLVSENHQLREQFQVDERRIADLLDDNHNQEEALRSSERAKADVENRLLD 1284 Query: 1359 YKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEI-- 1416 + + E+++ + +L+ S ++ ++ ++ +LELK EI Sbjct: 1285 LQDVHEENLRHAKNVTTELQNSYKMIEQLKIKHTEDMDMLNRRLEDVIEELELKSQEITS 1344 Query: 1417 YQKTHEYTITLTQRNDEFE---NVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHY 1473 Q E L ++ E + QL E ++ + E ++ + ++K + Sbjct: 1345 MQNELEEKTALVSKSMSEEVKLGLETQLAELSTKLTEA--EDKAHAQLEKMKKYAAVAKK 1402 Query: 1474 ETMQ-KESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIE 1532 +T Q +E E + +L E LN++ E N+++ E +E+ + EM L ++E Sbjct: 1403 KTAQCEELETKLRELEESLNLEKIEKELRNRELHEAIAGHQEKDNRIVEMDEELRRIQVE 1462 Query: 1533 IVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDA 1583 + ++ +R ++ K+ + + +D + + ++++A Sbjct: 1463 RDEAVQNVEAIKQELRQATDKLSTMNEEMQELSEAKDNARELGVRMQVIEA 1513 Score = 171 bits (415), Expect = 2e-40 Identities = 297/1476 (20%), Positives = 628/1476 (42%), Gaps = 106/1476 (7%) Query: 144 VTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXX 203 V LS+ +++KDN ++ L K+ +E I+DLQE + EKD +I++K KA T Sbjct: 179 VMELSH-VQDKDNKITELSNKIFELEAVIIDLQENLKEKDSVIDSKTKAITLMSADLSMK 237 Query: 204 XXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAA 263 EDTK +M MQENF+ +E+ K +K + +E ++ EA K E Sbjct: 238 GKTTLDTLEDTKDEMRSMQENFVLVESSLK-KKAEQIATLEENVQSLTEKLEAQKQAETV 296 Query: 264 RFEIS------LEHSKLAQE--LEQXXXXXXXXXXXXXXLAKQ----SIEPSCEEKTEIE 311 + S L +K A + E L KQ I+ + E + Sbjct: 297 SADFSRSTMDTLADTKDAMKSMQENFVLIETSLKSKNEHLLKQLEEREIKLAESEARILN 356 Query: 312 EKGSLEI---ANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSP 368 + L I N+ E+T K++ LE +N +++ EL+ +A + + K +S+ S+ Sbjct: 357 LETGLGIERQPNVEEITYKVDKLEEMNRKLQDEKYELQKNIAEL--QDKIISTESRTDES 414 Query: 369 LISRKSGRNTASKMKSPWSQLSSETLNQDTD-KKINKNEIAKLEMVIQSLNKDLVDKEYV 427 ++ N ++++S +L + + + K N++A++ ++L+ +V+ E Sbjct: 415 IME----DNRIAELESLIEELKKSNQHLEEEYKAALHNQVAEMNERNETLSNKIVELEKQ 470 Query: 428 ISEKDTXXXXXXXXXXGKDTLIAQLQLEHQ---QHMEGPSLIHVGTNTEDVNEIAKVQEQ 484 +++ +T + + Q + +E + + + N++ +Q+Q Sbjct: 471 VNDVTNDKIELESKLSAIETEAPKEDEQVQKLTKELEELNKSMIKLKAQHKNKLKNLQKQ 530 Query: 485 LKQELNDEIKDVNVKDLIEKLKSAEEQITQLN------DEIDAANKNMIKVKSNHKLKLK 538 L+ K+ + L ++ EE+ L DE+ A+ + + ++ + K+ Sbjct: 531 LENFKKVSDKNAELVKLGNQVALLEEEKGNLQLSLVDFDELKASAGDWKERIADLEGKVA 590 Query: 539 QMQKTID-NFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESD 597 K I+ + ++ + + L +ELH + Q+V+ LE E + V + ++++ + Sbjct: 591 SQAKEIETHIEAIAILENQKLDLMQELHAVKQEVSSLEAENAESENLRVTAEM-KVVDLE 649 Query: 598 VYKKMIEMENLAETRLKAISL-LESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVC 656 + + + AE A + + Q +L QE L QK ++E+ + ++ Sbjct: 650 EEIESLHKQQQAEPLTDAERIEFQRQIENLTQENERLSQKVSKLEELKSSSEVGSTESFV 709 Query: 657 SEIKSVHLEEQIDALS--ASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNY- 713 +V E +A + A K +L I+ L + L + E +++ Sbjct: 710 KTGSNVDSTESFEAFAADADKADLLRKIDGLTRENGALLEKLTRFEEKGSSDTGSTESFE 769 Query: 714 -IQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELS 772 I E+ + T +LE ++ E EL+ K+ E+ ++ D K+QE E + ++L Sbjct: 770 RIPEHGESTSRLENLTRENY-ELVVKLTKLEEKLAASE--ADTKLQEVLQENERLVAKLK 826 Query: 773 KYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQE-KQKAYSEYTIQEDELVNRLA-VL 830 + + +EE V E R +E ++E +A +E ++ E + L Sbjct: 827 QLEENAV-VEE--VVREKRSVEVEEVPRTQEPEIEETSSEAPTEVLVESTESPPHIVDEL 883 Query: 831 MDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANR-TDLA 889 + ++ L I E +EL K + Q LQ+ + + + + A + A Sbjct: 884 VAKIEELKSSLEAIGREKEELAAKLKEKEPVAQELQVEETIVPAEASVVKSSAQQDPSEA 943 Query: 890 ESESTKYQTQ-LRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVL-- 946 E +S Q++ + LE ++R T LI ++K IEDL+ + + E R L Sbjct: 944 ELKSDAVQSEAIAALEREIERCT----ALIAEQKAVIEDLKTKLADKEEELERKSAQLAS 999 Query: 947 NEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEEL-NKMNL-----ELIDKHVQKQQTQS 1000 +E ++++ L +L+E + I E+ KM + + I++ Q QT++ Sbjct: 1000 SESHDQDQLDAHVLRRELEESASEIAEWKHKCAEMEEKMKVLEKGRQHIEEGFQALQTEN 1059 Query: 1001 PDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENM 1060 + EQ ++ L+ L ++ D I K + AQ +++ E + + +E Sbjct: 1060 KNLLEQSEHKDVMLSQLKEELDHTISDFEAK-SRAQ---GEVIASQEQLVEELRKNVEEK 1115 Query: 1061 EEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKET--KLTFEMNIPKTEGMIISSTI 1118 + E+Q QL + +ELQ + + Q+++ T LT E+ +T ++ + Sbjct: 1116 DLELQGKYSQLQNDLIKMDELQDKLARLEAQVQQRDATIASLTEEVETLRTNASVVEEDL 1175 Query: 1119 EPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVL-QEQSAKLNTELQECYTKIIQ 1177 ++ ++ E+ + ++++L +E KL+ +L E Q Sbjct: 1176 FMARHQLTDLHEKLKDSKSLEEYNQLMEQ---LNDKTMLVEELETKLSQKLAEVNALKAQ 1232 Query: 1178 LETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSS--ISSAVDQRGFEI 1235 +E+L +E H + Q Q+++ ++ L +N N LRSS + V+ R ++ Sbjct: 1233 VESLVSE--NHQLREQFQVDE--RRIADLLDDNHN---QEEALRSSERAKADVENRLLDL 1285 Query: 1236 AELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKI-VTMEQVTS 1294 ++ +++L + + ++ ++ + + K+ + +D + ++ ++ + +++TS Sbjct: 1286 QDVHEENLRHAKNVTTELQNSYKM-IEQLKIKHTEDMDMLNRRLEDVIEELELKSQEITS 1344 Query: 1295 LQNKLQDKEEHL-RNLQEKY-ADVINQIEILRSEI-EDEKVAFXXXXXXXXXXXXXXXXD 1351 +QN+L++K + +++ E+ + Q+ L +++ E E A Sbjct: 1345 MQNELEEKTALVSKSMSEEVKLGLETQLAELSTKLTEAEDKAHAQLEKMKKYAAVAKKKT 1404 Query: 1352 LRTENQSYKQMQEQSILNINEENAQLK-KSSXXXXXXXXXXXXRV--NDAEAKVLELTHQ 1408 + E K + + LN+ + +L+ + R+ D E + +++ Sbjct: 1405 AQCEELETKLRELEESLNLEKIEKELRNRELHEAIAGHQEKDNRIVEMDEELRRIQVERD 1464 Query: 1409 LELKDSE-IYQKTHEYTITLTQRNDEFE------------NVRQQLVEYEKRIEDLTY-- 1453 +++ E I Q+ + T L+ N+E + VR Q++E E I+ L Sbjct: 1465 EAVQNVEAIKQELRQATDKLSTMNEEMQELSEAKDNARELGVRMQVIEAE-YIDQLAQIN 1523 Query: 1454 EKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALE 1513 +E IL K + E ++KESE R +L + K E + + + Sbjct: 1524 SLRAENGILLSKQTQINERLENVEKESEERRAQLEKYEKQKEIEETQRAEAAVQQAQTCG 1583 Query: 1514 EEVAKTNEMQTALENQEIEIVTLNDEITN-LQNMVR 1548 E +K ++ L+ ++ EI L++E+ N + N+V+ Sbjct: 1584 ECASKVQALEAKLQERDAEIENLDNELHNSIGNLVQ 1619 Score = 137 bits (331), Expect = 3e-30 Identities = 254/1255 (20%), Positives = 534/1255 (42%), Gaps = 134/1255 (10%) Query: 476 NEIAKVQEQLKQELNDEIKDVNVK--DLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNH 533 NEI + + + Q L +++ +N + DL E ++ L+D+ A+N+ +++ +S + Sbjct: 1888 NEIQETRATIDQ-LTEQLTSLNAQREDLARLASDREAELKALHDQFAASNQAILQSRSEY 1946 Query: 534 KL---KLKQMQKTIDNFSKVSDSNKEIVR-LTEELHHLSQ--KVAELEEEKGNLQ----- 582 + KL+Q+Q S + K V L EL ++AELE + Sbjct: 1947 EQLVGKLEQLQSANHELSAAEEVYKNRVHELETELRTSGDNARIAELENRLARITSERDI 2006 Query: 583 LHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQ-QKYDEVE 641 L L DS R E K M+ L + + + +L++ +K L QEL L+ K + V Sbjct: 2007 LQLQVNDSTRAFED---LKEESMQGLKQLQARIETLIQ-EKNQLTQELETLRVAKPEAVS 2062 Query: 642 DKL--ADISQLQSDQVCSEIKSVHL-----EEQIDALSASKKELALVIENLKLDKEQLYG 694 ++ A + + ++++ + E+ D S K + +E +D + Sbjct: 2063 EQFVQAATAPVAETVPAPKLEAAAMGDSMWEDDEDPWGLSDKTIPHSVEQ-HVDIPMVLS 2121 Query: 695 TIKDLENDKEDIMNKLQNYIQENMDLTD--KLEKMS----AEKISELLAKINH-EEQSKI 747 L+ +++ KL+ +EN L + K+ ++ +K+ E + + + Q K Sbjct: 2122 AETQLKLQVDELEEKLRELTEENAKLIEEGKVAQVKNVKYVKKLKEYKVQFDSLQRQLKS 2181 Query: 748 QTQFG----IDAKIQER-DLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQL 802 Q G +D+ I+E ++ +E L++ K+ ++ + +R L ++ Sbjct: 2182 QKSMGGFGDLDSAIEEELKSQVDALEKALTESKAETKKIAAEKEKLLNRIDVLTAATERF 2241 Query: 803 GSYLQEKQKAYSEYTIQEDELVNRLAVL------MDHDRVVEKQLLE----IEHENKELQ 852 +++ + ++ EL +L L D ++ E E E KEL+ Sbjct: 2242 TEAKEKQDTEVHIWQMRYKELEMKLQQLDFGPETKDSTTSPPQERAERDPKYEEELKELK 2301 Query: 853 KKNQILLEENQNLQISLSDMQQHYNALVEKANR-TDLAESESTKYQTQLRDLESNLKRIT 911 + L EN+ LQ L + + VE++++ T+ E+++ + + L+ + + + Sbjct: 2302 DSVEALAAENEELQQLLEENRTKRQTSVEESSKKTNELEAKNVELLSNNEKLKGDYETLR 2361 Query: 912 HEHQTLIVQKKKEIEDLE-----IEFNTQIESAIRDKKV--LNEKYEKNIEYVTQLEAQL 964 +++ ++ +++ + I+ +++ DK V LNE+ + +E TQLE ++ Sbjct: 2362 KQYEQSLMDANDQVQSMRQNCELIKAEYVEKTSEHDKTVAELNERLQTVLEEKTQLEGKV 2421 Query: 965 QEYKNNIENLNMNVEELNKMNLELIDKHVQ-----KQQTQSPDYTEQYINEINKLNALLK 1019 Q ++ +E +N ++++ EL++ VQ K++ Q + + E + A ++ Sbjct: 2422 QGLESEVERINNATTYTDELS-ELLNARVQEVAGLKEELQRLLQDKTQLEENTR--ATIQ 2478 Query: 1020 QKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNE 1079 Q EE+ K + + +++ + ++ + +LE + + +V+ L + + Sbjct: 2479 QLTEELHDKQDKFDALNTA----IAEKDGEILRQAAELEELRGLVDKVNGLELSIEGYTT 2534 Query: 1080 ELQILVREQDDQIKELKETKLTFEMNIPKTEGMIIS--STIEPMSDDANNVDXXXXXXXX 1137 ++Q EQ+++++ L++ +E+ + + E + S S ++ + + Sbjct: 2535 QVQ----EQNEELETLRDKLRQYEVALTEKEQQVSSQQSQLQQSLSETQQCNTQVQEQHE 2590 Query: 1138 XXXXLKVQEEE--EFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQ 1195 L V E E Q S + LN+ L E + Q + L V + + Sbjct: 2591 LAQRLAVAETHVAELTQRLSEAENHIQNLNSALSEKEAHLAQDGEESRRLQDELQVKEAE 2650 Query: 1196 INQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEH 1255 + ++KSKLE + S V R ISS Q ++ + + D ++ ++ Sbjct: 2651 LAEVKSKLEAAVQAQEQAASQV---RKEISSIQQQPSVKVIDELPVFTFGSDNDDKELQN 2707 Query: 1256 ELRVQLSAFESKYEQLLDSVQSSTQEETNKIVT--MEQVTSLQNKLQDKEEHLRNLQEKY 1313 LR +L A + E L ++ S +T +I+ + + +L N+ + E + + ++ Sbjct: 2708 -LRAELRAKNEEIEHLQYAINES---QTTRIIQELQDNINALYNEKAELESQVISKNQEI 2763 Query: 1314 ADVINQIEILRSE--------IEDEKVAFXXXXXXXXXXXXXXXXD-LRTENQSY-KQMQ 1363 + Q++ LRS ED++ F + TE +S ++ Sbjct: 2764 NGLKFQLDELRSHQHQPVKRSAEDQEELFKLQNELHIRDQELNELRYVVTEKESQLREAL 2823 Query: 1364 EQSILNINEENA--QLKKSSXXXXXXXXXXXXRVNDAEAKVLELT-------------HQ 1408 EQ+ N + + +LK V+D +++V L + Sbjct: 2824 EQASGNAEQHESVEKLKSDLYEKQQELENLKFTVSDLQSEVANLRGLERLAGEDRATIER 2883 Query: 1409 LELKDSEIYQKTHEYTI-TLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMH 1467 L + E+ ++ E L ++ E +N++QQL + + + +E ++ L+L++ Sbjct: 2884 LSSEKEEVRREAQEAVERVLREKEQEIDNLKQQLAAENQSLMEALGLRERDIENLKLQIE 2943 Query: 1468 ENANHYETM---------QKESEI-ERVKLIEELNV-KITESVSLNKQVAELNKALEEEV 1516 + ++ E+E+ ER + + EL++ K TE ++ Q++E N EE V Sbjct: 2944 QTGLDRDSQLDQRADQVAHLEAELSERDRRLAELSITKDTEIHNIRVQLSEKNARFEELV 3003 Query: 1517 AKT-------NEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRD 1569 A T +EM+ LE +E +I L ++ +Q+HV+ + + + Sbjct: 3004 ALTEEEERQLSEMRKLLEVKEQQINGLTQQLDEKSKEYELMQHALQRHVTKSDQSTEITQ 3063 Query: 1570 EQLDNTMNKEL-LDAVPRA---ELDLAMYMLHQRDVRCXXXXXXXXXXXXXRDTL 1620 +QL+ + + +DA + ELDLA+YMLHQRDVRC RDTL Sbjct: 3064 QQLEQSASSAAAMDAASSSSANELDLALYMLHQRDVRCEELTHELMQLLEERDTL 3118 Score = 113 bits (273), Expect = 3e-23 Identities = 271/1426 (19%), Positives = 573/1426 (40%), Gaps = 136/1426 (9%) Query: 223 ENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXX 282 E I A +++K L++++ + +SSLE N E R ++ L +E+E Sbjct: 597 ETHIEAIAILENQKLDLMQELHAVKQEVSSLEAENAESENLRVTAEMKVVDLEEEIESLH 656 Query: 283 XXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTN 342 + + E T+ E+ S +++ + EL E+ + +N Sbjct: 657 KQQQAEPLTDA--ERIEFQRQIENLTQENERLSQKVSKLEELKSSSEVGSTESFVKTGSN 714 Query: 343 KELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKI 402 + ++ K ++R++G K+ + SS+T + ++ ++I Sbjct: 715 VDSTESFEAFAADADKADLLRKIDG--LTRENGA-LLEKLTRFEEKGSSDTGSTESFERI 771 Query: 403 NKN--EIAKLEMVIQSLNKDLVDKEYVISEK---DTXXXXXXXXXXGKDTLIAQL-QLEH 456 ++ ++LE + + N +LV K + EK + L+A+L QLE Sbjct: 772 PEHGESTSRLENLTRE-NYELVVKLTKLEEKLAASEADTKLQEVLQENERLVAKLKQLEE 830 Query: 457 QQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEI-KDVNVKDL-------------I 502 +E ++ + E V E+ + QE +E + E +V V+ I Sbjct: 831 NAVVE--EVVREKRSVE-VEEVPRTQEPEIEETSSEAPTEVLVESTESPPHIVDELVAKI 887 Query: 503 EKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTE 562 E+LKS+ E I + +E+ A K V +++ + + + L Sbjct: 888 EELKSSLEAIGREKEELAAKLKEKEPVAQELQVEETIVPAEASVVKSSAQQDPSEAELKS 947 Query: 563 ELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQ 622 + S+ +A LE E + + + + D+ K+ + E E K+ L S+ Sbjct: 948 DAVQ-SEAIAALEREIERCTALIAEQ---KAVIEDLKTKLADKEE--ELERKSAQLASSE 1001 Query: 623 KFDLVQ-ELHILQQKYDEVEDKLAD----ISQLQSDQVCSEIKSVHLEEQIDALSASKKE 677 D Q + H+L+++ +E ++A+ ++++ E H+EE AL K Sbjct: 1002 SHDQDQLDAHVLRRELEESASEIAEWKHKCAEMEEKMKVLEKGRQHIEEGFQALQTENKN 1061 Query: 678 LALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLA 737 L E+ + QL + +D E I L ++L K EK EL Sbjct: 1062 LLEQSEHKDVMLSQLKEELDHTISDFEAKSRAQGEVIASQEQLVEELRKNVEEKDLELQG 1121 Query: 738 KINHEE-----QSKIQTQFG-IDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDR 791 K + + ++Q + ++A++Q+RD I ++ E+ ++ +EE + + + Sbjct: 1122 KYSQLQNDLIKMDELQDKLARLEAQVQQRDATIASLTEEVETLRTNASVVEEDLFMARHQ 1181 Query: 792 RYSLERKADQLGSYLQEKQ--KAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENK 849 L K S + Q + ++ T+ +EL +L+ + ++ Q+ + EN Sbjct: 1182 LTDLHEKLKDSKSLEEYNQLMEQLNDKTMLVEELETKLSQKLAEVNALKAQVESLVSENH 1241 Query: 850 ELQKKNQI-------LLEENQNLQISLSDMQQH----YNAL--VEKANRTDL--AESEST 894 +L+++ Q+ LL++N N + +L ++ N L ++ + +L A++ +T Sbjct: 1242 QLREQFQVDERRIADLLDDNHNQEEALRSSERAKADVENRLLDLQDVHEENLRHAKNVTT 1301 Query: 895 KYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFN--TQIESAIRDKKVLNEKYEK 952 + Q + +E + T + L + + IE+LE++ T +++ + +K L K Sbjct: 1302 ELQNSYKMIEQLKIKHTEDMDMLNRRLEDVIEELELKSQEITSMQNELEEKTALVSK-SM 1360 Query: 953 NIEYVTQLEAQLQEYKNNI----ENLNMNVEELNKMNLELIDKHVQKQQTQSP-DYTEQY 1007 + E LE QL E + + + +E++ K K Q ++ ++ E+ Sbjct: 1361 SEEVKLGLETQLAELSTKLTEAEDKAHAQLEKMKKYAAVAKKKTAQCEELETKLRELEES 1420 Query: 1008 IN-----------EINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYES---KLAQF 1053 +N E+++ A ++KD I+ +++++ QV V + E+ +L Q Sbjct: 1421 LNLEKIEKELRNRELHEAIAGHQEKDNRIVEMDEELRRIQVERDEAVQNVEAIKQELRQA 1480 Query: 1054 TTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMI 1113 T KL M EEMQ +S+ ++++ +Q++ E DQ+ ++ N + E I Sbjct: 1481 TDKLSTMNEEMQELSEAKDNARELGVRMQVIEAEYIDQLAQI---------NSLRAENGI 1531 Query: 1114 ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYT 1173 + S +++ NV+ + Q+E E Q +Q+ EC + Sbjct: 1532 LLSKQTQINERLENVEKESEERRAQLEKYEKQKEIEETQRAEAAVQQAQTCG----ECAS 1587 Query: 1174 KIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNL-LSTV-AELRSSISSAVDQR 1231 K+ + L +L D + N+L + + L +NL LST+ A +S+ + ++ Sbjct: 1588 KV---QALEAKLQERDAEIENLDNELHNSIGNLVQMQENLRLSTIPAAPDASMQESYNEL 1644 Query: 1232 GFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQ 1291 + L + + +A ++ T HE +L ++ ++L ++Q + ++ ++ Sbjct: 1645 MLQYNVLTATN-EEMKAKYEATLHE-NEELLERVARLQELNVTMQERIESVERELARDKE 1702 Query: 1292 VTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIED---EKVAFXXXXXXXXXXXXXX 1348 V + + + + L+EKY +++E +S++ + A Sbjct: 1703 VAA---SFDETHQQYQELREKYEQQRSELETAQSKLREAIASSEASERNLQSTIELLQHE 1759 Query: 1349 XXDLRTENQSYKQMQEQSIL------------NINEENAQLKKSSXXXXXXXXXXXXRVN 1396 L EN++ K +++ +IL IN E AQ + V+ Sbjct: 1760 KEQLEEENKNLKIVKDNNILLDDSWGDDASSSMINVE-AQPQIRPEPVTETMERHKREVD 1818 Query: 1397 DAEAKVLELTHQLELKDSEIY---------QKTHEYTITLTQRNDEFENVRQQLVEYEKR 1447 A V E + Q L D+ I+ K + + DE +R QL + Sbjct: 1819 QAAVPVSEESSQPPLFDASIFGASPPQPSSSKNAQLEFEMGLLRDEVSVLRNQLDQARSA 1878 Query: 1448 IEDLTYEKESELAILRLKMHENANHYETMQKESE-IERVKLIEELNVKI--TESVSLNKQ 1504 E++ +E+ R + + ++ + E + R+ E +K + + N+ Sbjct: 1879 TEEVQARMGNEIQETRATIDQLTEQLTSLNAQREDLARLASDREAELKALHDQFAASNQA 1938 Query: 1505 VAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRAS 1550 + + E+ V K ++Q+A + + L+ +R S Sbjct: 1939 ILQSRSEYEQLVGKLEQLQSANHELSAAEEVYKNRVHELETELRTS 1984 Score = 104 bits (249), Expect = 2e-20 Identities = 291/1593 (18%), Positives = 653/1593 (40%), Gaps = 159/1593 (9%) Query: 73 EHRKATAELLGRPFVPGISESLANTLKQKEILMEKIKQYKELSKRSSTTIVRXXXXXXXX 132 E K++ E +GR E LA LK+KE + +++ Q +E + ++V+ Sbjct: 888 EELKSSLEAIGRE-----KEELAAKLKEKEPVAQEL-QVEETIVPAEASVVKSSAQQDPS 941 Query: 133 XXXXXXXQLGDVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNK- 191 +L S I + + + + I DL+ K+ +K++ +E K+ Sbjct: 942 EA-----ELKSDAVQSEAIAALEREIERCTALIAEQKAVIEDLKTKLADKEEELERKSAQ 996 Query: 192 -ATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWK---DEKQRLLKDIESKD 247 A++ E++ ++ + + ME + K +Q + + ++ Sbjct: 997 LASSESHDQDQLDAHVLRRELEESASEIAEWKHKCAEMEEKMKVLEKGRQHIEEGFQALQ 1056 Query: 248 VRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEK 307 +L E ++ + ++ E + E L ++ + + EEK Sbjct: 1057 TENKNLLEQSEHKDVMLSQLKEELDHTISDFEAKSRAQGEVIASQEQLVEE-LRKNVEEK 1115 Query: 308 T-EIEEKGSL---EIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPS 363 E++ K S ++ M EL K+ LE Q T L ++ T+ T + V Sbjct: 1116 DLELQGKYSQLQNDLIKMDELQDKLARLEAQVQQRDATIASLTEEVETLRTNASVVEEDL 1175 Query: 364 KKGSPLISRKSGRNTASKMKSPWSQLSSET-----LNQDTDKKINKN--EIAKLEMVIQS 416 ++ + SK ++QL + L ++ + K+++ E+ L+ ++S Sbjct: 1176 FMARHQLTDLHEKLKDSKSLEEYNQLMEQLNDKTMLVEELETKLSQKLAEVNALKAQVES 1235 Query: 417 LNKD--LVDKEYVISEK---DTXXXXXXXXXXGKDTLIAQLQLEHQ----QHMEGPSLIH 467 L + + +++ + E+ D + + A+ +E++ Q + +L H Sbjct: 1236 LVSENHQLREQFQVDERRIADLLDDNHNQEEALRSSERAKADVENRLLDLQDVHEENLRH 1295 Query: 468 VGTNTEDVNEIAKVQEQLKQELNDEIKDVN--VKDLIEKLKSAEEQITQLNDEIDAANKN 525 T ++ K+ EQLK + +++ +N ++D+IE+L+ ++IT + +E++ Sbjct: 1296 AKNVTTELQNSYKMIEQLKIKHTEDMDMLNRRLEDVIEELELKSQEITSMQNELEEKTAL 1355 Query: 526 MIKVKSNH-KLKLK-QMQKTIDNFSKVSD-SNKEIVRLTEELHHLSQKVAELEEEKGNLQ 582 + K S KL L+ Q+ + ++ D ++ ++ ++ + +K A+ EE + L+ Sbjct: 1356 VSKSMSEEVKLGLETQLAELSTKLTEAEDKAHAQLEKMKKYAAVAKKKTAQCEELETKLR 1415 Query: 583 LHLVDYDSGRMIESDVYKKMI--------EMENLAETRLKAISLLESQKFDLVQELHILQ 634 L + + IE ++ + + E +N + + ++ ++ + VQ + ++ Sbjct: 1416 -ELEESLNLEKIEKELRNRELHEAIAGHQEKDNRIVEMDEELRRIQVERDEAVQNVEAIK 1474 Query: 635 QKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLK------LD 688 Q+ + DKL+ +++ + ++ + L ++ + A + I +L+ L Sbjct: 1475 QELRQATDKLSTMNEEMQELSEAKDNARELGVRMQVIEAEYIDQLAQINSLRAENGILLS 1534 Query: 689 KE-QLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKI 747 K+ Q+ ++++E + E+ +L+ Y ++ ++E+ + + A+ E SK+ Sbjct: 1535 KQTQINERLENVEKESEERRAQLEKYEKQK-----EIEETQRAEAAVQQAQTCGECASKV 1589 Query: 748 QTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESI----------AVMEDRRYSLER 797 Q ++AK+QERD IEN+++EL + +++E++ A M++ L Sbjct: 1590 QA---LEAKLQERDAEIENLDNELHNSIGNLVQMQENLRLSTIPAAPDASMQESYNELML 1646 Query: 798 KADQLGSYLQEKQKAYSEYTIQE-DELVNRLAVLMDHDRVVEKQLLEIEHE---NKELQK 853 + + L + E+ KA E T+ E +EL+ R+A L + + +++++ +E E +KE+ Sbjct: 1647 QYNVL-TATNEEMKAKYEATLHENEELLERVARLQELNVTMQERIESVERELARDKEVAA 1705 Query: 854 KNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHE 913 ++ Q L+ + K R +A SE+++ R+L+S ++ + HE Sbjct: 1706 SFDETHQQYQELREKYEQQRSELETAQSKL-REAIASSEASE-----RNLQSTIELLQHE 1759 Query: 914 HQTLIVQKK--KEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNI 971 + L + K K ++D I + ++N + + I E ++ +K + Sbjct: 1760 KEQLEEENKNLKIVKDNNILLDDSWGDD-ASSSMINVEAQPQIRPEPVTET-MERHKREV 1817 Query: 972 ENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQK 1031 + + V E L D + P ++ E LL+ +E+ L + Sbjct: 1818 DQAAVPVSE-ESSQPPLFDASIFGASPPQPSSSKNAQLEFEM--GLLR---DEVSVLRNQ 1871 Query: 1032 INNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQ 1091 ++ A+ + + + +++ + ++ + E++ ++ Q D + + + ++ DQ Sbjct: 1872 LDQARSATEEVQARMGNEIQETRATIDQLTEQLTSLNAQREDLARLASDREAELKALHDQ 1931 Query: 1092 I----KELKETKLTFEMNIPKTEGMIISSTIEPMSDDA--NNVDXXXXXXXXXXXXLKVQ 1145 + + +++ +E + K E + ++ +++ N V ++ Sbjct: 1932 FAASNQAILQSRSEYEQLVGKLEQLQSANHELSAAEEVYKNRVHELETELRTSGDNARIA 1991 Query: 1146 EEE----EFIQERSVLQEQSAKLNTELQECYTKIIQ-LETLNTELTGHDVVNQEQINQLK 1200 E E ER +LQ Q ++ + +Q L+ L + + + QE+ NQL Sbjct: 1992 ELENRLARITSERDILQLQVNDSTRAFEDLKEESMQGLKQLQARI---ETLIQEK-NQLT 2047 Query: 1201 SKLEQLNTENDNLLST--VAELRSSISSAVDQRGFEIA----ELWKQ------------- 1241 +LE L +S V + ++ V E A +W+ Sbjct: 2048 QELETLRVAKPEAVSEQFVQAATAPVAETVPAPKLEAAAMGDSMWEDDEDPWGLSDKTIP 2107 Query: 1242 HLAQREADFQ---KTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNK 1298 H ++ D E +L++Q+ E K +L + +++ E K+ ++ V ++ K Sbjct: 2108 HSVEQHVDIPMVLSAETQLKLQVDELEEKLRELTE--ENAKLIEEGKVAQVKNVKYVK-K 2164 Query: 1299 LQDKEEHLRNLQE--KYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTEN 1356 L++ + +LQ K + L S IE+E + + E Sbjct: 2165 LKEYKVQFDSLQRQLKSQKSMGGFGDLDSAIEEELKSQVDALEKALTESKAETKKIAAEK 2224 Query: 1357 QSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDS-- 1414 + K + +L E + ++ R + E K+ +L E KDS Sbjct: 2225 E--KLLNRIDVLTAATE--RFTEAKEKQDTEVHIWQMRYKELEMKLQQLDFGPETKDSTT 2280 Query: 1415 ----EIYQKTHEYTITLTQRNDEFENVR------QQLVEYEKRIEDLTYEKESELA-ILR 1463 E ++ +Y L + D E + QQL+E + + E+ S+ L Sbjct: 2281 SPPQERAERDPKYEEELKELKDSVEALAAENEELQQLLEENRTKRQTSVEESSKKTNELE 2340 Query: 1464 LKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQ 1523 K E ++ E ++ + E R K E+ + + V +Q EL KA E V KT+E Sbjct: 2341 AKNVELLSNNEKLKGDYETLR-KQYEQSLMDANDQVQSMRQNCELIKA--EYVEKTSEHD 2397 Query: 1524 TALENQEIEIVTLNDEITNLQNMVRASSSKIQK 1556 + + T+ +E T L+ V+ S++++ Sbjct: 2398 KTVAELNERLQTVLEEKTQLEGKVQGLESEVER 2430 Score = 103 bits (246), Expect = 5e-20 Identities = 232/1188 (19%), Positives = 479/1188 (40%), Gaps = 110/1188 (9%) Query: 461 EGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEID 520 E P + G E V + + EQ K +L + +KD+ +++ + LK EE++ + +++ Sbjct: 7 EPPGTMEAGP-PESVANLKETCEQSKNQL-ESVKDIMLRNK-QSLKKKEEELEEYANKLS 63 Query: 521 AAN---------KNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKV 571 K+ S K K T + V D + + L +K+ Sbjct: 64 KFKTRAKASRTPKDDAASSSESTPKSKSDTSTAEPSDDVVDDISQAKTPKAKSSLLQKKL 123 Query: 572 AELEEEKGNLQLHLVDYDSGRMIESDV--YKKMIEMENLAETRLKAISLLESQKFDLVQE 629 AE + L + S R +E V ++ +E +A + + L+ SQ V E Sbjct: 124 AEDRKIFEQRSKELTE--SKRAVEEKVEALRQQLEERYVAPVSVVSPVLVTSQGAHPVME 181 Query: 630 LHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDK 689 L +Q K +++ + I +L++ V +++ +L+E+ + + K + L+ +L + Sbjct: 182 LSHVQDKDNKITELSNKIFELEA--VIIDLQE-NLKEKDSVIDSKTKAITLMSADLSMKG 238 Query: 690 EQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSA--EKISELLAKINHEEQSKI 747 + T+ LE+ K+++ + +N++ L K E+++ E + L K+ ++Q++ Sbjct: 239 KT---TLDTLEDTKDEMRSMQENFVLVESSLKKKAEQIATLEENVQSLTEKLEAQKQAET 295 Query: 748 QTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQ 807 + A + L+ K + ++E+ ++E SL+ K + L L+ Sbjct: 296 -----VSADFSRSTM------DTLADTKDAMKSMQENFVLIET---SLKSKNEHLLKQLE 341 Query: 808 EKQKAYSEYTIQEDELVNRLAVLMDHD-RVVEKQLLEIEHENKELQKKNQILLEENQNLQ 866 E++ +E + L L + + + ++ ++E N++LQ + L + LQ Sbjct: 342 EREIKLAESEARILNLETGLGIERQPNVEEITYKVDKLEEMNRKLQDEKYELQKNIAELQ 401 Query: 867 ISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIE 926 + + + + + NR ES + + + LE K H + ++ + + Sbjct: 402 DKIISTESRTDESIMEDNRIAELESLIEELKKSNQHLEEEYKAALHNQVAEMNERNETLS 461 Query: 927 DLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNL 986 + +E Q+ DK L K ++ +E + + ++ L +EELNK + Sbjct: 462 NKIVELEKQVNDVTNDKIELESK-------LSAIETEAPKEDEQVQKLTKELEELNKSMI 514 Query: 987 ELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVS-------- 1038 +L +H K + ++ + +++ NA L + ++ L ++ N Q+S Sbjct: 515 KLKAQH--KNKLKNLQKQLENFKKVSDKNAELVKLGNQVALLEEEKGNLQLSLVDFDELK 572 Query: 1039 -----YMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIK 1093 + ++D E K+A ++E E + + Q LD Q ++ V + + Sbjct: 573 ASAGDWKERIADLEGKVASQAKEIETHIEAIAILENQKLDLMQELHAVKQEVSSLEAENA 632 Query: 1094 ELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQE 1153 E + ++T EM + E I S + ++ + + QE E Q+ Sbjct: 633 ESENLRVTAEMKVVDLEEEIESLHKQQQAEPLTDAERIEFQRQIENL---TQENERLSQK 689 Query: 1154 RSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNL 1213 S L+E + E + K +TE + ++ + L+ K++ L EN L Sbjct: 690 VSKLEELKSSSEVGSTESFVK-TGSNVDSTESFEAFAADADKADLLR-KIDGLTRENGAL 747 Query: 1214 LSTVAELRSSISSAVDQRGFEIAELWKQH--LAQREADFQKTEHELRVQLSAFESKY--- 1268 L + SS D E E +H R + + +EL V+L+ E K Sbjct: 748 LEKLTRFEEKGSS--DTGSTESFERIPEHGESTSRLENLTRENYELVVKLTKLEEKLAAS 805 Query: 1269 --EQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDK-----EEHLR----NLQEKYADVI 1317 + L V + K+ +E+ ++ +++K EE R ++E ++ Sbjct: 806 EADTKLQEVLQENERLVAKLKQLEENAVVEEVVREKRSVEVEEVPRTQEPEIEETSSEAP 865 Query: 1318 NQIEILRSE----IEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQM-QEQSI-LNIN 1371 ++ + +E I DE VA +L + + + + QE + I Sbjct: 866 TEVLVESTESPPHIVDELVAKIEELKSSLEAIGREKEELAAKLKEKEPVAQELQVEETIV 925 Query: 1372 EENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQK---THEYTITLT 1428 A + KSS +EA + L ++E + I ++ + L Sbjct: 926 PAEASVVKSSAQQDPSEAELKSDAVQSEA-IAALEREIERCTALIAEQKAVIEDLKTKLA 984 Query: 1429 QRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHY-ETMQKESEI-ERVK 1486 + +E E QL E +D + + +LR ++ E+A+ E K +E+ E++K Sbjct: 985 DKEEELERKSAQLASSESHDQD-----QLDAHVLRRELEESASEIAEWKHKCAEMEEKMK 1039 Query: 1487 LIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNM 1546 ++E+ I E + + NK L E+ + M + L+ + ++ + + Q Sbjct: 1040 VLEKGRQHIEEGF---QALQTENKNLLEQSEHKDVMLSQLKEELDHTISDFEAKSRAQGE 1096 Query: 1547 VRASS----SKIQKHVSFASDTKQGRDEQLDNTMNK--ELLDAVPRAE 1588 V AS +++K+V QG+ QL N + K EL D + R E Sbjct: 1097 VIASQEQLVEELRKNVEEKDLELQGKYSQLQNDLIKMDELQDKLARLE 1144 Score = 97.9 bits (233), Expect = 2e-18 Identities = 167/851 (19%), Positives = 375/851 (44%), Gaps = 91/851 (10%) Query: 481 VQEQLKQELNDEIKDVNVKDLIEKLKSA--------EEQITQLNDEIDAANKNMIKVKSN 532 V+E K+ E K+V + EKLK E+ + ND++ + +N +K+ Sbjct: 2329 VEESSKKTNELEAKNVELLSNNEKLKGDYETLRKQYEQSLMDANDQVQSMRQNCELIKAE 2388 Query: 533 HKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDS-G 591 + ++KT ++ V++ N+ + + EE L KV LE E + D Sbjct: 2389 Y------VEKTSEHDKTVAELNERLQTVLEEKTQLEGKVQGLESEVERINNATTYTDELS 2442 Query: 592 RMIES---DVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLA--D 646 ++ + +V E++ L + + + + L +ELH Q K+D + +A D Sbjct: 2443 ELLNARVQEVAGLKEELQRLLQDKTQLEENTRATIQQLTEELHDKQDKFDALNTAIAEKD 2502 Query: 647 ISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLE---NDK 703 L+ E++ L ++++ L S + ++ + E L ++ E +K Sbjct: 2503 GEILRQAAELEELRG--LVDKVNGLELSIEGYTTQVQEQNEELETLRDKLRQYEVALTEK 2560 Query: 704 EDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLY 763 E ++ Q+ +Q+++ T + E+ EL ++ E + + ++ E + + Sbjct: 2561 EQQVSSQQSQLQQSLSETQQCNTQVQEQ-HELAQRLAVAETHVAE----LTQRLSEAENH 2615 Query: 764 IENIESELSKYKSRICRLEESIAVMED----RRYSLERKADQLGSYLQEKQKAYSEY--- 816 I+N+ S LS+ ++ + + E ++D + L +L + +Q +++A S+ Sbjct: 2616 IQNLNSALSEKEAHLAQDGEESRRLQDELQVKEAELAEVKSKLEAAVQAQEQAASQVRKE 2675 Query: 817 --TIQED---ELVNRLAVLM----DHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQI 867 +IQ+ ++++ L V + D+ ++ E+ +N+E++ Q + E+Q +I Sbjct: 2676 ISSIQQQPSVKVIDELPVFTFGSDNDDKELQNLRAELRAKNEEIEHL-QYAINESQTTRI 2734 Query: 868 SLSDMQQHYNALV-EKANRTDLAESESTKYQTQLRDLESNLKRI-THEHQTLIVQKKKEI 925 + ++Q + NAL EKA ES+ ++ L+ L + +H+HQ + K+ Sbjct: 2735 -IQELQDNINALYNEKAE----LESQVISKNQEINGLKFQLDELRSHQHQPV----KRSA 2785 Query: 926 EDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMN 985 ED E F Q E IRD+++ +Y VT+ E+QL+E +E + N E+ + Sbjct: 2786 EDQEELFKLQNELHIRDQELNELRY-----VVTEKESQLRE---ALEQASGNAEQHESVE 2837 Query: 986 LELIDKHVQKQQTQSPDYTEQYI-NEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVS 1044 D + ++Q+ ++ +T + +E+ L L + E+ + + + + Sbjct: 2838 KLKSDLYEKQQELENLKFTVSDLQSEVANLRGLERLAGEDRATIERLSSEKEEVRREAQE 2897 Query: 1045 DYESKLAQFTTKLENMEEEMQRVSKQLLDS----KQHNEELQILVR----EQDDQIKELK 1096 E L + +++N+++++ ++ L+++ ++ E L++ + ++D Q+ + Sbjct: 2898 AVERVLREKEQEIDNLKQQLAAENQSLMEALGLRERDIENLKLQIEQTGLDRDSQLDQRA 2957 Query: 1097 ETKLTFEMNIPKTEGMIISSTIEPMSDDAN-NVDXXXXXXXXXXXXLKVQEEEEFIQE-R 1154 + E + + + + +I ++ N V +EEE + E R Sbjct: 2958 DQVAHLEAELSERDRRLAELSITKDTEIHNIRVQLSEKNARFEELVALTEEEERQLSEMR 3017 Query: 1155 SVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLL 1214 +L+ + ++N Q+ K + E + L H + + + +LEQ Sbjct: 3018 KLLEVKEQQINGLTQQLDEKSKEYELMQHALQRHVTKSDQSTEITQQQLEQ-------SA 3070 Query: 1215 STVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDS 1274 S+ A + ++ SS+ ++ ++A L+ H QR+ ++ HEL L ++ +L ++ Sbjct: 3071 SSAAAMDAASSSSANE--LDLA-LYMLH--QRDVRCEELTHELMQLLEERDTLQLRLSNA 3125 Query: 1275 VQSSTQEETNK 1285 ++ EE K Sbjct: 3126 IR--VNEELRK 3134 Score = 90.6 bits (215), Expect = 3e-16 Identities = 283/1586 (17%), Positives = 623/1586 (39%), Gaps = 119/1586 (7%) Query: 62 ENAALVSKRIKEHRKATAELLGRPFVPGISESLANTLKQKEILMEKIKQYKELSKRSST- 120 E ALVSK + E K E + +S L + +EK+K+Y ++K+ + Sbjct: 1351 EKTALVSKSMSEEVKLGLETQ----LAELSTKLTEAEDKAHAQLEKMKKYAAVAKKKTAQ 1406 Query: 121 -----TIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNALSVLQVKMKIMETTILDL 175 T +R + ++ +EKDN + + +++ ++ ++ Sbjct: 1407 CEELETKLRELEESLNLEKIEKELRNRELHEAIAGHQEKDNRIVEMDEELRRIQ---VER 1463 Query: 176 QEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDE 235 E + + I + +AT ++ ++ +MQ +EAE+ D+ Sbjct: 1464 DEAVQNVEAIKQELRQATDKLSTMNEEMQELSEAK-DNARELGVRMQ----VIEAEYIDQ 1518 Query: 236 KQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXL 295 ++ + +S + N+ LE + E + +LE+ Sbjct: 1519 LAQINSLRAENGILLSKQTQINERLE----NVEKESEERRAQLEKYEKQKEIEETQRAEA 1574 Query: 296 AKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEH-LNCQIRQTNKELEN-KLATMG 353 A Q + E ++++ +LE A + E +IE L++ L+ I + EN +L+T+ Sbjct: 1575 AVQQAQTCGECASKVQ---ALE-AKLQERDAEIENLDNELHNSIGNLVQMQENLRLSTIP 1630 Query: 354 TESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMV 413 A S ++ T +MK+ + E N++ +++ + + + M Sbjct: 1631 AAPDA-SMQESYNELMLQYNVLTATNEEMKAKYEATLHE--NEELLERVARLQELNVTMQ 1687 Query: 414 --IQSLNKDLV-DKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGT 470 I+S+ ++L DKE S +T + + +LE Q ++ Sbjct: 1688 ERIESVERELARDKEVAASFDETHQQYQELREKYEQQ---RSELETAQSKLREAIASSEA 1744 Query: 471 NTEDVNEIAKVQEQLKQELNDEIKDVN-VKD---LIEKLKSAEEQITQLNDEIDAANKN- 525 + ++ ++ + K++L +E K++ VKD L++ + + +N E + Sbjct: 1745 SERNLQSTIELLQHEKEQLEEENKNLKIVKDNNILLDDSWGDDASSSMINVEAQPQIRPE 1804 Query: 526 -MIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLH 584 + + HK ++ Q + S + S K A+LE E G L+ Sbjct: 1805 PVTETMERHKREVDQAAVPVSEESSQPPLFDASIFGASPPQPSSSKNAQLEFEMGLLRDE 1864 Query: 585 LV----DYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYD-E 639 + D R +V +M + ETR L E Q + + D E Sbjct: 1865 VSVLRNQLDQARSATEEVQARM--GNEIQETRATIDQLTEQLTSLNAQREDLARLASDRE 1922 Query: 640 VEDKLADISQLQSDQVCSEIKSVH--LEEQIDALSASKKELALVIENLKLDKEQLYGTIK 697 E K S+Q + +S + L +++ L ++ EL+ E K +L ++ Sbjct: 1923 AELKALHDQFAASNQAILQSRSEYEQLVGKLEQLQSANHELSAAEEVYKNRVHELETELR 1982 Query: 698 DLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKI-QTQFGIDAK 756 D I +L+N + D L+ + + + E + Q Q I+ Sbjct: 1983 T-SGDNARIA-ELENRLARITSERDILQ-LQVNDSTRAFEDLKEESMQGLKQLQARIETL 2039 Query: 757 IQERDLYIENIESELSKYKSRICR--LEESIAVMEDRRYSLERKADQLGSYLQEKQK--- 811 IQE++ + +E+ + ++ + A + + + + +A +G + E + Sbjct: 2040 IQEKNQLTQELETLRVAKPEAVSEQFVQAATAPVAETVPAPKLEAAAMGDSMWEDDEDPW 2099 Query: 812 AYSEYTIQED-ELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQI--- 867 S+ TI E + +++ + ++ Q+ E+E + +EL ++N L+EE + Q+ Sbjct: 2100 GLSDKTIPHSVEQHVDIPMVLSAETQLKLQVDELEEKLRELTEENAKLIEEGKVAQVKNV 2159 Query: 868 ----SLSDMQQHYNALVE--KANRT-----DLAESESTKYQTQLRDLESNLKRITHEHQT 916 L + + +++L K+ ++ DL + + ++Q+ LE L E + Sbjct: 2160 KYVKKLKEYKVQFDSLQRQLKSQKSMGGFGDLDSAIEEELKSQVDALEKALTESKAETKK 2219 Query: 917 LIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNM 976 + +K+K + +++ +K E + + Y +LE +LQ+ E + Sbjct: 2220 IAAEKEKLLNRIDVLTAATERFTEAKEKQDTEVHIWQMRY-KELEMKLQQLDFGPETKDS 2278 Query: 977 NVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQ----KDEEIIALNQKI 1032 + D +++ + D E E +L LL++ + + ++K Sbjct: 2279 TTSPPQERAER--DPKYEEELKELKDSVEALAAENEELQQLLEENRTKRQTSVEESSKKT 2336 Query: 1033 NNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNE----ELQILVREQ 1088 N + + ++S+ E + T + E+ + + Q+ +Q+ E E E Sbjct: 2337 NELEAKNVELLSNNEKLKGDYETLRKQYEQSLMDANDQVQSMRQNCELIKAEYVEKTSEH 2396 Query: 1089 DDQIKELKETKLTFEMNIPKTEGMI--ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQE 1146 D + EL E T + EG + + S +E +++ D + + Sbjct: 2397 DKTVAELNERLQTVLEEKTQLEGKVQGLESEVERINNATTYTDELSELLNARVQEVAGLK 2456 Query: 1147 EE--EFIQERSVLQEQS-AKLNTELQECYTKIIQLETLNTELTGHD--VVNQ----EQIN 1197 EE +Q+++ L+E + A + +E + K + + LNT + D ++ Q E++ Sbjct: 2457 EELQRLLQDKTQLEENTRATIQQLTEELHDKQDKFDALNTAIAEKDGEILRQAAELEELR 2516 Query: 1198 QLKSKLEQLNTENDNLLSTVAELRSSISSAVDQ-RGFEIAELWK-QHLAQREADFQKTEH 1255 L K+ L + + V E + + D+ R +E+A K Q ++ +++ Q++ Sbjct: 2517 GLVDKVNGLELSIEGYTTQVQEQNEELETLRDKLRQYEVALTEKEQQVSSQQSQLQQSLS 2576 Query: 1256 ELRVQLSAFESKYE--QLLDSVQSSTQEETNKIVTME-QVTSLQNKLQDKEEHLRNLQEK 1312 E + + + ++E Q L ++ E T ++ E + +L + L +KE HL E+ Sbjct: 2577 ETQQCNTQVQEQHELAQRLAVAETHVAELTQRLSEAENHIQNLNSALSEKEAHLAQDGEE 2636 Query: 1313 YADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQ--SYKQMQEQSILNI 1370 + +++++ +E+ + K ++ + Q S K + E + Sbjct: 2637 SRRLQDELQVKEAELAEVKSKLEAAVQAQEQAASQVRKEISSIQQQPSVKVIDELPVFTF 2696 Query: 1371 NEEN-----AQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTI 1425 +N L+ +N E++ + +L+ + +Y + E Sbjct: 2697 GSDNDDKELQNLRAELRAKNEEIEHLQYAIN--ESQTTRIIQELQDNINALYNEKAELES 2754 Query: 1426 TLTQRNDEFENVRQQLVEYEK-RIEDLTYEKESELAILRLKMHENANHYETMQKESEIER 1484 + +N E ++ QL E + + + E + + +L +N H Q+ +E+ Sbjct: 2755 QVISKNQEINGLKFQLDELRSHQHQPVKRSAEDQEELFKL---QNELHIRD-QELNELRY 2810 Query: 1485 VKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQ 1544 V + E ++ E++ AE ++++E+ + E Q LEN + + L E+ NL+ Sbjct: 2811 V--VTEKESQLREALEQASGNAEQHESVEKLKSDLYEKQQELENLKFTVSDLQSEVANLR 2868 Query: 1545 NMVRASSSKIQKHVSFASDTKQGRDE 1570 + R + +S+ ++ R E Sbjct: 2869 GLERLAGEDRATIERLSSEKEEVRRE 2894 Score = 48.0 bits (109), Expect = 0.002 Identities = 142/746 (19%), Positives = 309/746 (41%), Gaps = 65/746 (8%) Query: 143 DVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXX 202 +V ++N D +L +++ + +LQ + +K Q+ E +AT Sbjct: 2427 EVERINNATTYTDELSELLNARVQEVAGLKEELQRLLQDKTQL-EENTRATIQQLTEELH 2485 Query: 203 XXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRI----SSLEEANK 258 D ++ I +A +E + L+ + ++ I + ++E N+ Sbjct: 2486 DKQDKF----DALNTAIAEKDGEILRQAAELEELRGLVDKVNGLELSIEGYTTQVQEQNE 2541 Query: 259 LLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEI 318 LE R ++ L ++ +Q Q +E+ E+ ++ ++ Sbjct: 2542 ELETLRDKLRQYEVALTEKEQQVSSQQSQLQQSLSET--QQCNTQVQEQHELAQRLAVAE 2599 Query: 319 ANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSK-KGSPLISRKSGRN 377 ++ ELT+++ E+ + E E LA G ES+ + + K + L KS Sbjct: 2600 THVAELTQRLSEAENHIQNLNSALSEKEAHLAQDGEESRRLQDELQVKEAELAEVKSKLE 2659 Query: 378 TA-SKMKSPWSQLSSE--TLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTX 434 A + SQ+ E ++ Q K+ +E+ + +K+L + + K+ Sbjct: 2660 AAVQAQEQAASQVRKEISSIQQQPSVKV-IDELPVFTFGSDNDDKELQNLRAELRAKNEE 2718 Query: 435 XXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQE--QLKQELNDE 492 T ++ E Q ++ +L + E I+K QE LK +L DE Sbjct: 2719 IEHLQYAINESQT--TRIIQELQDNIN--ALYNEKAELES-QVISKNQEINGLKFQL-DE 2772 Query: 493 IKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSD 552 ++ + +++ +E++ +L +E+ ++ + +++ K Q+++ ++ S ++ Sbjct: 2773 LRS-HQHQPVKRSAEDQEELFKLQNELHIRDQELNELRYVVTEKESQLREALEQASGNAE 2831 Query: 553 SNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETR 612 ++ + +L +L+ +K ELE NL+ + D ++S+V + +E LA Sbjct: 2832 QHESVEKLKSDLY---EKQQELE----NLKFTVSD------LQSEV-ANLRGLERLAGED 2877 Query: 613 LKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALS 672 I L S+K ++ +E ++ + +K +I L+ Q+ +E +S L E + Sbjct: 2878 RATIERLSSEKEEVRREAQEAVERV--LREKEQEIDNLK-QQLAAENQS--LMEALGLRE 2932 Query: 673 ASKKELALVIENLKLDK----EQLYGTIKDLENDKEDIMNKLQNY-IQENMDLTDKLEKM 727 + L L IE LD+ +Q + LE + + +L I ++ ++ + ++ Sbjct: 2933 RDIENLKLQIEQTGLDRDSQLDQRADQVAHLEAELSERDRRLAELSITKDTEIHNIRVQL 2992 Query: 728 SAE--KISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESI 785 S + + EL+A EE+ + + ++ K Q+ + + ++ + +Y+ L+ + Sbjct: 2993 SEKNARFEELVALTEEEERQLSEMRKLLEVKEQQINGLTQQLDEKSKEYELMQHALQRHV 3052 Query: 786 AVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIE 845 + +++ +Q S A S + D LA+ M H R V + E+ Sbjct: 3053 TKSDQSTEITQQQLEQSASSAAAMDAASSSSANELD-----LALYMLHQRDVRCE--ELT 3105 Query: 846 HENKELQKKNQILLEENQNLQISLSD 871 HE + LLEE LQ+ LS+ Sbjct: 3106 HELMQ-------LLEERDTLQLRLSN 3124 >UniRef50_A2EYA1 Cluster: Viral A-type inclusion protein, putative; n=1; Trichomonas vaginalis G3|Rep: Viral A-type inclusion protein, putative - Trichomonas vaginalis G3 Length = 1662 Score = 197 bits (481), Expect = 2e-48 Identities = 283/1371 (20%), Positives = 634/1371 (46%), Gaps = 92/1371 (6%) Query: 213 DTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHS 272 + +++ ++QE E +K + + K IE +IS+ +E +K +A + +++ E Sbjct: 196 ELEEKDAEIQELKEQNEGAYKMKYETATKTIELLQKQISASQEISKENDALKSKLA-EKD 254 Query: 273 KLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLE 332 K Q L+K +I+ S + E E+K EI N+ + ++++ + Sbjct: 255 KQLQNYNDMNSLIKEQREQIEKLSK-NIDDS-SDFAENEKKYQNEIQNLKKQIEELQEND 312 Query: 333 HLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSE 392 + I T+ E++ + + E + + + +K+ L + K K + +E Sbjct: 313 NAWGDIDDTD-EIKQENENLKKEIENLKNQNKEIGNLQLQIEKLKDIIKEK----ESDNE 367 Query: 393 TLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTL---- 448 +L Q+ +K N EI K++ Q+L + + + I E ++ K L Sbjct: 368 SLLQELEKSENNFEIEKIKKENQNLQTKVKEMQETIDELESNAWNDDGNDEIKQNLDKLK 427 Query: 449 --IAQLQLEHQ----QHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVK--- 499 I L+ E++ Q E N +++ EI + E+L++E N+ +K +N + Sbjct: 428 QEINNLKKENENLQKQVEENEENAWNDGNNDEIEEIKQNLEKLQKE-NENLKKINEEKSN 486 Query: 500 -DLIEKLKSAEEQITQLNDEI------DAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSD 552 D I KLK ++ + N+E+ + N++ + SN K + +++++ I K + Sbjct: 487 DDEINKLKQEISELKKENEELQENLWNENENEDNQEEISNLKKENEKLKQNIKELQKQIE 546 Query: 553 SNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETR 612 +N+E + E + L QKV ELE E N L + ++ E++ KK E+++L E Sbjct: 547 TNEENL-WNENENDLKQKVTELESEVKNSD-KLKEENNKLKKENEELKK--EIDDLTENV 602 Query: 613 LKAISLLESQKFD-LVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDAL 671 K ++Q+ + L QE++ L+++ +E++ ++ ++ + ++ +E +S L++++ L Sbjct: 603 WKDDE--DNQETEKLKQEINNLKKENEELKKEMDELQESTWNESYTE-ESDELKQKLKEL 659 Query: 672 SASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLE-KMSAE 730 K+ E+LK EQ + +L+ + E I L+ I+EN + +D E ++ + Sbjct: 660 EQKYKDTEKSNEDLKKLLEQ----VDNLQKESEKINQDLEKQIEENQENSDVDENEILKQ 715 Query: 731 KISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMED 790 K++EL +++ +E+ + + + +E + EN +E + + +LE+ +++ Sbjct: 716 KVTELESEVKEKEKLNEELKKENEDLKKEVENLQENAWNETENEEIKE-KLEKENEILQK 774 Query: 791 RRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEK------QLLEI 844 + + + L L E + S + D+L ++ + ++ + Q L++ Sbjct: 775 QVEENNKTLNDLKQKLSESENEKSVKNSENDKLKQKVTEIESDFKISNEKSSNLQQKLDV 834 Query: 845 EHENKE-LQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRD- 902 +N E L+K+ +I E+NQ LQ SD+Q + +L ++ + L + K +++L + Sbjct: 835 LSQNLEKLEKEMKISSEKNQKLQKENSDLQNQFTSLQKQNSDNQLKITSLLKEKSELENQ 894 Query: 903 LESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIE--YVTQL 960 L N + + + +KEI DL+ + Q E K L E+ +K + + Sbjct: 895 LNENSTQNLESNSS-----EKEIRDLKEKITKQNEKI----KELEEEVKKGYQDLWGADS 945 Query: 961 EAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQ 1020 + +E I+NL + +E++NK +LE I V+K++ + E N+I K+ L++ Sbjct: 946 DDDSKEKDEEIKNLKLEIEKINKNHLEKIGI-VEKEKKNEIEKRE---NKIKKMRIDLQK 1001 Query: 1021 KDEEIIALNQKIN-NAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNE 1079 KDEEI LN++I+ N + + ++ + +++ + E +++E+ K++ + +Q Sbjct: 1002 KDEEINKLNKEISQNKKDEWSTVTFGDDEEISSLKKENERIKQEITEKQKEIEEIQQ--- 1058 Query: 1080 ELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXX 1139 +L +E +++ E+ K E + E + ++ ++ N+ Sbjct: 1059 KLSKFTKENEEKSSEISLLKKENEEKLSVLEKE--NEELKQRIEEFNSFKKENEENKQKI 1116 Query: 1140 XXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQ-LETLNTELTGHDVVNQEQINQ 1198 L +E ++ + E SVL++++ +L +L E ++ Q + N + + N+E+++ Sbjct: 1117 YNLG-EETKKKLNEISVLKKENEELKQKLNEINEEMKQKIVDFNEKFSNSKKENEEKLSV 1175 Query: 1199 LKSK---LEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQH--LAQREADFQKT 1253 LK + L+Q E ++ + E + ++ ++ +++ L K++ + Q +D K Sbjct: 1176 LKKENDNLKQKLNEFNSFMKESEENKQRLNDLGEETKKKLSILKKENEEMKQNISDLMKE 1235 Query: 1254 EHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKY 1313 EL +LS + E+ + + + E N +E+ + L+ + ++ ++ L + ++ Sbjct: 1236 NKELNERLSKSIKENEE---NKKKLNENELNFKQEIEENSLLKKENEENKQKLNEINQEM 1292 Query: 1314 ADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEE 1373 +N+I L+ E ED K + + + ++ K+M++ I + +E Sbjct: 1293 KKKLNEISNLKRENEDLKRSLNGNEEIIEEMNEINKENDSIKKEN-KEMKQNLIPKLQKE 1351 Query: 1374 NAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDE 1433 N +L ++ + + E++ QL+ +++E +++ + + ND+ Sbjct: 1352 NEKLNNEISQIQIENEKLKKQIEEMKQISNEIS-QLK-QENEDLKRSLNGNQEINKENDD 1409 Query: 1434 FENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENAN-HYETMQKESEIERVKLIEELN 1492 + ++L + + ++ +K + +L+ EN QK+ E E++ EEL Sbjct: 1410 LKKENEKLNQKMEEMKKSLVDKSNLNELLKKLQKENEELSISLSQKQKENEKIN--EELT 1467 Query: 1493 VKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNL 1543 K + + KQ +L L A +EM L+N+ E N+E++ L Sbjct: 1468 KK---QIEIEKQ-KDLETNLNNSDANKDEMIELLQNENEETKRNNEELSLL 1514 Score = 184 bits (449), Expect = 1e-44 Identities = 273/1379 (19%), Positives = 599/1379 (43%), Gaps = 126/1379 (9%) Query: 213 DTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHS 272 +T + ++ + I+ E E L + KD ++ + + N L++ R +I + S Sbjct: 220 ETATKTIELLQKQISASQEISKENDALKSKLAEKDKQLQNYNDMNSLIKEQREQIE-KLS 278 Query: 273 KLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKT--EIEEKGSLEIANMTELTKKIEL 330 K + L KQ E + +I++ ++ N L K+IE Sbjct: 279 KNIDDSSDFAENEKKYQNEIQNLKKQIEELQENDNAWGDIDDTDEIKQEN-ENLKKEIEN 337 Query: 331 LEHLNCQIRQTNKELENK---LATMGTESKAVSSPSKKGSPLIS----RKSGRNTASKMK 383 L++ N +I ++E + ++++++ +K +K +N +K+K Sbjct: 338 LKNQNKEIGNLQLQIEKLKDIIKEKESDNESLLQELEKSENNFEIEKIKKENQNLQTKVK 397 Query: 384 SPWS---QLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXX 440 +L S N D + +I +N + KL+ I +L K+ + + + E + Sbjct: 398 EMQETIDELESNAWNDDGNDEIKQN-LDKLKQEINNLKKENENLQKQVEENEENAWNDGN 456 Query: 441 XXXGKDTL--IAQLQLEHQQ----HMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIK 494 ++ + +LQ E++ + E + + ++++E+ K E+L++ L +E + Sbjct: 457 NDEIEEIKQNLEKLQKENENLKKINEEKSNDDEINKLKQEISELKKENEELQENLWNENE 516 Query: 495 DVNVKDLIEKLKSAEEQITQ----LNDEIDAANKNMIKVKSNH-KLKLKQMQKTIDNFSK 549 + + ++ I LK E++ Q L +I+ +N+ N K K+ +++ + N K Sbjct: 517 NEDNQEEISNLKKENEKLKQNIKELQKQIETNEENLWNENENDLKQKVTELESEVKNSDK 576 Query: 550 VSDSNKEIVRLTEELHHLSQKVAE--LEEEKGNLQLHLVDYDSGRMI-ESDVYKKMIEME 606 + + N ++ + EEL + E ++++ N + + + + E++ KK EM+ Sbjct: 577 LKEENNKLKKENEELKKEIDDLTENVWKDDEDNQETEKLKQEINNLKKENEELKK--EMD 634 Query: 607 NLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQL--QSDQVCSEIKSVH- 663 L E+ ES +L Q+L L+QKY + E D+ +L Q D + E + ++ Sbjct: 635 ELQESTWNESYTEESD--ELKQKLKELEQKYKDTEKSNEDLKKLLEQVDNLQKESEKINQ 692 Query: 664 -LEEQIDALSASK--------KELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYI 714 LE+QI+ + K+ +E+ +KE+L ++L+ + ED+ +++N Sbjct: 693 DLEKQIEENQENSDVDENEILKQKVTELESEVKEKEKLN---EELKKENEDLKKEVENLQ 749 Query: 715 QENMDLTDKLE-KMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSK 773 + + T+ E K EK +E+L K EE +K E + ++N E++ K Sbjct: 750 ENAWNETENEEIKEKLEKENEILQK-QVEENNKTLNDLKQKLSESENEKSVKNSEND--K 806 Query: 774 YKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDH 833 K ++ +E + ++ +L++K D L L++ +K E I ++ N+ Sbjct: 807 LKQKVTEIESDFKISNEKSSNLQQKLDVLSQNLEKLEK---EMKISSEK--NQ------- 854 Query: 834 DRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESES 893 +++ EN +LQ + L ++N + Q+ ++ + + + L + N ES Sbjct: 855 ---------KLQKENSDLQNQFTSLQKQNSDNQLKITSLLKEKSELENQLNENSTQNLES 905 Query: 894 TKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDL----EIEFNTQIESAIRDKKVLNEK 949 + ++RDL+ + + + + L + KK +DL + + + + I++ K+ EK Sbjct: 906 NSSEKEIRDLKEKITKQNEKIKELEEEVKKGYQDLWGADSDDDSKEKDEEIKNLKLEIEK 965 Query: 950 YEKN-IEYVTQLEA----QLQEYKNNIENLNMNV----EELNKMNLELIDKHVQKQQTQS 1000 KN +E + +E ++++ +N I+ + +++ EE+NK+N E+ + T + Sbjct: 966 INKNHLEKIGIVEKEKKNEIEKRENKIKKMRIDLQKKDEEINKLNKEISQNKKDEWSTVT 1025 Query: 1001 PDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENM 1060 E+ I+ + K N +KQ EI ++I Q + E K ++ + + Sbjct: 1026 FGDDEE-ISSLKKENERIKQ---EITEKQKEIEEIQQKLSKFTKENEEKSSEISLLKKEN 1081 Query: 1061 EEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEP 1120 EE++ + K+ + KQ EE +E ++ + K L E E ++ E Sbjct: 1082 EEKLSVLEKENEELKQRIEEFNSFKKENEE--NKQKIYNLGEETKKKLNEISVLKKENEE 1139 Query: 1121 MSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLET 1180 + N ++ ++E ++ SVL++++ L +L E + + + E Sbjct: 1140 LKQKLNEINEEMKQKIVDFNEKFSNSKKENEEKLSVLKKENDNLKQKLNEFNSFMKESEE 1199 Query: 1181 LNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWK 1240 L +++++ LK + E++ +L+ EL +S ++ + E K Sbjct: 1200 NKQRLNDLGEETKKKLSILKKENEEMKQNISDLMKENKELNERLSKSIKEN-----EENK 1254 Query: 1241 QHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVT-SLQNKL 1299 + L + E +F K E E L + +Q L+ + +++ N+I +++ L+ L Sbjct: 1255 KKLNENELNF-KQEIEENSLLKKENEENKQKLNEINQEMKKKLNEISNLKRENEDLKRSL 1313 Query: 1300 QDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSY 1359 EE + + E + + + ++ E ++ K ++ EN+ Sbjct: 1314 NGNEEIIEEMNE----INKENDSIKKENKEMKQNLIPKLQKENEKLNNEISQIQIENEKL 1369 Query: 1360 KQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQK 1419 K+ Q + + I+ E +QLK+ + R + ++ + L+ ++ ++ QK Sbjct: 1370 KK-QIEEMKQISNEISQLKQEN--------EDLKRSLNGNQEINKENDDLKKENEKLNQK 1420 Query: 1420 THEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKE 1479 E +L ++ N+ + L + +K E+L+ + K +E N E +K+ Sbjct: 1421 MEEMKKSLVDKS----NLNELLKKLQKENEELSISLSQ-----KQKENEKINE-ELTKKQ 1470 Query: 1480 SEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTN-EMQTALENQEIEIVTLN 1537 EIE+ K +L + S + ++ EL + EE + N E+ LE + ++ +LN Sbjct: 1471 IEIEKQK---DLETNLNNSDANKDEMIELLQNENEETKRNNEELSLLLEKYKHDVDSLN 1526 Score = 172 bits (419), Expect = 6e-41 Identities = 261/1388 (18%), Positives = 611/1388 (44%), Gaps = 127/1388 (9%) Query: 235 EKQRLLKDIESKDVRISSLEEANKLL--EAARFEISLEHSKLA-QELEQXXXXXXXXXXX 291 E + K+ + ++ I L N L E + LE QEL++ Sbjct: 161 EMTQKTKEFSNLEIIIKELRAENDQLNDELMNDQAELEEKDAEIQELKEQNEGAYKMKYE 220 Query: 292 XXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLAT 351 + ++ EI ++ + + E K+++ +N I++ +++E Sbjct: 221 TATKTIELLQKQISASQEISKENDALKSKLAEKDKQLQNYNDMNSLIKEQREQIEKLSKN 280 Query: 352 MGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLS--------SETLNQDTDKKIN 403 + S + K + + + K + + W + +E L ++ + N Sbjct: 281 IDDSSDFAENEKKYQNEIQNLKKQIEELQENDNAWGDIDDTDEIKQENENLKKEIENLKN 340 Query: 404 KN-EIAKLEMVIQSLNKDLV-----DKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQ 457 +N EI L++ I+ L KD++ D E ++ E + K+ Q +++ Sbjct: 341 QNKEIGNLQLQIEKL-KDIIKEKESDNESLLQELEKSENNFEIEKIKKENQNLQTKVKEM 399 Query: 458 QHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLND 517 Q L N + +EI + ++LKQE+N N+K E L+ E+ + N Sbjct: 400 QETID-ELESNAWNDDGNDEIKQNLDKLKQEIN------NLKKENENLQKQVEE-NEENA 451 Query: 518 EIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEE 577 D N + ++K N L+++QK +N K+++ +E++ L Q+++EL++E Sbjct: 452 WNDGNNDEIEEIKQN----LEKLQKENENLKKINEEKSN----DDEINKLKQEISELKKE 503 Query: 578 KGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQEL-HILQQK 636 LQ +L + + + ++ E E L + + +E+ + +L E + L+QK Sbjct: 504 NEELQENLWNENENEDNQEEISNLKKENEKLKQNIKELQKQIETNEENLWNENENDLKQK 563 Query: 637 YDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTI 696 E+E ++ + +L+ + + ++ L+++ID L+ E + + E+L I Sbjct: 564 VTELESEVKNSDKLKEENNKLKKENEELKKEIDDLT----ENVWKDDEDNQETEKLKQEI 619 Query: 697 KDLENDKEDIMNKLQNYIQE---NMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGI 753 +L+ + E++ ++ +QE N T++ +++ +K+ EL K E+S + Sbjct: 620 NNLKKENEELKKEMDE-LQESTWNESYTEESDELK-QKLKELEQKYKDTEKSNEDLK--- 674 Query: 754 DAKIQERDLYIENIESELSKYKSRICR-LEESIAVME-DRRYSLERKADQLGSYLQEKQK 811 K+ E+ ++N++ E K + + +EE+ + D L++K +L S ++EK+K Sbjct: 675 --KLLEQ---VDNLQKESEKINQDLEKQIEENQENSDVDENEILKQKVTELESEVKEKEK 729 Query: 812 AYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSD 871 E + ++L + L ++ E E ++L+K+N+IL ++ + +L+D Sbjct: 730 LNEELKKENEDLKKEVENLQEN----AWNETENEEIKEKLEKENEILQKQVEENNKTLND 785 Query: 872 MQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIE 931 ++Q L E N + SE+ K + ++ ++ES+ K I++E + + QK L++ Sbjct: 786 LKQK---LSESENEKSVKNSENDKLKQKVTEIESDFK-ISNEKSSNLQQK------LDV- 834 Query: 932 FNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDK 991 + +E ++ K+ +EK +K + + L+ Q + + + + L K EL + Sbjct: 835 LSQNLEKLEKEMKISSEKNQKLQKENSDLQNQFTSLQKQNSDNQLKITSLLKEKSEL-EN 893 Query: 992 HVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLA 1051 + + TQ+ + EI L + +++E+I L +++ SD +SK Sbjct: 894 QLNENSTQNLESNSSE-KEIRDLKEKITKQNEKIKELEEEVKKGYQDLWGADSDDDSK-- 950 Query: 1052 QFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEG 1111 + +++N++ E+++++K H E++ I+ +E+ ++I E +E K+ +M I Sbjct: 951 EKDEEIKNLKLEIEKINKN------HLEKIGIVEKEKKNEI-EKRENKIK-KMRID---- 998 Query: 1112 MIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQEC 1171 ++ ++ N ++ ++E E S L++++ ++ E+ E Sbjct: 999 ------LQKKDEEINKLNKEISQNKKDEWSTVTFGDDE---EISSLKKENERIKQEITE- 1048 Query: 1172 YTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQR 1231 K ++E + +L+ N+E+ S++ L EN+ LS + + + +++ Sbjct: 1049 --KQKEIEEIQQKLSKFTKENEEK----SSEISLLKKENEEKLSVLEKENEELKQRIEE- 1101 Query: 1232 GFEIAELWKQHLAQREADF-QKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTM- 1289 F + + Q+ + ++T+ +L ++S + + E+L + +E KIV Sbjct: 1102 -FNSFKKENEENKQKIYNLGEETKKKLN-EISVLKKENEELKQKLNEINEEMKQKIVDFN 1159 Query: 1290 EQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXX 1349 E+ ++ + + ++K L+ + +N+ E E+ K Sbjct: 1160 EKFSNSKKENEEKLSVLKKENDNLKQKLNEFNSFMKESEENKQRLNDLGEETKKKLSI-- 1217 Query: 1350 XDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQL 1409 L+ EN+ KQ +I ++ +EN +L + ++N+ E L + Sbjct: 1218 --LKKENEEMKQ----NISDLMKENKELNERLSKSIKENEENKKKLNENE-----LNFKQ 1266 Query: 1410 ELKDSEIYQKTHEYTIT-LTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHE 1468 E++++ + +K +E L + N E + ++ ++ EDL I+ +M+E Sbjct: 1267 EIEENSLLKKENEENKQKLNEINQEMKKKLNEISNLKRENEDLKRSLNGNEEIIE-EMNE 1325 Query: 1469 NANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAEL---NKALEEEVAKTNEMQTA 1525 ++++KE++ + LI +L E+ LN +++++ N+ L++++ + ++ Sbjct: 1326 INKENDSIKKENKEMKQNLIPKLQ---KENEKLNNEISQIQIENEKLKKQIEEMKQISNE 1382 Query: 1526 LENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVP 1585 + + E L + Q + + + +++ ++ + +D + ELL + Sbjct: 1383 ISQLKQENEDLKRSLNGNQEINKENDDLKKENEKLNQKMEEMKKSLVDKSNLNELLKKLQ 1442 Query: 1586 RAELDLAM 1593 + +L++ Sbjct: 1443 KENEELSI 1450 Score = 149 bits (362), Expect = 5e-34 Identities = 266/1255 (21%), Positives = 544/1255 (43%), Gaps = 125/1255 (9%) Query: 305 EEKTEIEEKGSLEIANMTELTKKIE-LLEHLNCQIRQTNKELENKLATMGTESKAVSSPS 363 +EK +K + + T + +E +L +N + ++E +L +SKA+ S Sbjct: 3 DEKNMDPQKMKVLLKQKTARIRDLEKMLSQMNAPSVDNSSKIE-ELEQQLEDSKALISAL 61 Query: 364 KKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVD 423 ++ +S+K N S SQ ++ N D + K +IA+ + I+SLN +L + Sbjct: 62 QES---VSQK---NAEISRLSLISQSNARNQNSDLIASLQK-KIAEQQQEIESLNNELWN 114 Query: 424 KEYVISEKD---TXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAK 480 + SEKD ++ + L + T++ + + Sbjct: 115 DDPNESEKDIEIQNLKSQIQKLTKNQPQVSPASNNAELDTLRSQLAEMTQKTKEFSNLEI 174 Query: 481 VQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQM 540 + ++L+ E ND++ D + D E L+ + +I +L ++ + A +K+K + Sbjct: 175 IIKELRAE-NDQLNDELMNDQAE-LEEKDAEIQELKEQNEGA----------YKMKYETA 222 Query: 541 QKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNL-QLHLVDYDSGRMIESDVY 599 KTI+ K +++EI ++E L K+AE +++ N ++ + + IE + Sbjct: 223 TKTIELLQKQISASQEI---SKENDALKSKLAEKDKQLQNYNDMNSLIKEQREQIEK-LS 278 Query: 600 KKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEI 659 K + + + AE K + +++ K ++EL + +++D +D++ E Sbjct: 279 KNIDDSSDFAENEKKYQNEIQNLK-KQIEELQENDNAWGDIDD---------TDEIKQE- 327 Query: 660 KSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMD 719 + +L+++I+ L KE I NL+L E+L IK+ E+D E ++ +L+ EN Sbjct: 328 -NENLKKEIENLKNQNKE----IGNLQLQIEKLKDIIKEKESDNESLLQELEK--SENNF 380 Query: 720 LTDKLEKMSAE---KISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKS 776 +K++K + K+ E+ I+ E +S G D +I++ ++ ++ E++ K Sbjct: 381 EIEKIKKENQNLQTKVKEMQETID-ELESNAWNDDGND-EIKQN---LDKLKQEINNLKK 435 Query: 777 RICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRV 836 L++ + E+ ++ + D++ Q +K E + + +N D Sbjct: 436 ENENLQKQVEENEENAWN-DGNNDEIEEIKQNLEKLQKEN--ENLKKINEEKSNDDEINK 492 Query: 837 VEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKY 896 +++++ E++ EN+ELQ+ L EN+N D Q+ + L +K N E Sbjct: 493 LKQEISELKKENEELQEN---LWNENEN-----EDNQEEISNL-KKEN-----EKLKQNI 538 Query: 897 QTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEY 956 + + +E+N + + +E++ + QK E+E E++ + +++ K NE+ +K I+ Sbjct: 539 KELQKQIETNEENLWNENENDLKQKVTELES-EVKNSDKLKEENNKLKKENEELKKEIDD 597 Query: 957 VTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNA 1016 +T+ + E E L + L K N EL + + Q + E Y E ++L Sbjct: 598 LTENVWKDDEDNQETEKLKQEINNLKKENEEL---KKEMDELQESTWNESYTEESDELKQ 654 Query: 1017 LLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQ 1076 LK+ +++ +K N + V + + + + LE EE Q S Sbjct: 655 KLKELEQK-YKDTEKSNEDLKKLLEQVDNLQKESEKINQDLEKQIEENQENS-----DVD 708 Query: 1077 HNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXX 1136 NE L+ V E + ++KE KE KL E+ K E + +E + ++A N Sbjct: 709 ENEILKQKVTELESEVKE-KE-KLNEEL---KKENEDLKKEVENLQENAWN--------- 754 Query: 1137 XXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQI 1196 +++E+ E +E +LQ+Q + N L + K+ + E + + ++++ Sbjct: 755 -ETENEEIKEKLE--KENEILQKQVEENNKTLNDLKQKLSESENEKSVKNSENDKLKQKV 811 Query: 1197 NQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHE 1256 +++S + N ++ NL + L ++ ++ +I+ Q L + +D Q Sbjct: 812 TEIESDFKISNEKSSNLQQKLDVLSQNLEKL--EKEMKISSEKNQKLQKENSDLQNQFTS 869 Query: 1257 LRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADV 1316 L+ Q S + K LL +S + + N+ T +L++ +KE +R+L+EK Sbjct: 870 LQKQNSDNQLKITSLLKE-KSELENQLNENSTQ----NLESNSSEKE--IRDLKEKITKQ 922 Query: 1317 INQIEILRSEI-EDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENA 1375 +I+ L E+ + + + +L+ E + + + I I E+ Sbjct: 923 NEKIKELEEEVKKGYQDLWGADSDDDSKEKDEEIKNLKLEIEKINKNHLEKI-GIVEKEK 981 Query: 1376 QLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFE 1435 + + + D E L KD E T ++ E E Sbjct: 982 KNEIEKRENKIKKMRIDLQKKDEEINKLNKEISQNKKD-EWSTVTFGDDEEISSLKKENE 1040 Query: 1436 NVRQQLVEYEKRIEDL-------TYEKESELAILRLKMHENANHYETMQKESEIERVKLI 1488 ++Q++ E +K IE++ T E E + + + L EN ++KE+E E + I Sbjct: 1041 RIKQEITEKQKEIEEIQQKLSKFTKENEEKSSEISLLKKENEEKLSVLEKENE-ELKQRI 1099 Query: 1489 EELNVKITESVSLNKQVAELNKALEEEVAKTNEMQT-ALENQEI--EIVTLNDEI 1540 EE N E+ +++ L EE K NE+ EN+E+ ++ +N+E+ Sbjct: 1100 EEFNSFKKENEENKQKIYNLG---EETKKKLNEISVLKKENEELKQKLNEINEEM 1151 Score = 142 bits (345), Expect = 5e-32 Identities = 260/1181 (22%), Positives = 504/1181 (42%), Gaps = 107/1181 (9%) Query: 471 NTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVK 530 N V+ +K++E L+Q+L D ++ K+AE L + +A N+N + Sbjct: 34 NAPSVDNSSKIEE-LEQQLEDSKALISALQESVSQKNAEISRLSLISQSNARNQNSDLIA 92 Query: 531 SNHKLKLKQMQKTIDNFS--------KVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQ 582 S K K+ + Q+ I++ + S+ + EI L ++ L++ ++ N + Sbjct: 93 SLQK-KIAEQQQEIESLNNELWNDDPNESEKDIEIQNLKSQIQKLTKNQPQVSPASNNAE 151 Query: 583 LHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFD-LVQELHILQQKYDEVE 641 L D+ R +++ +K E NL E +K + Q D L+ + L++K E++ Sbjct: 152 L-----DTLRSQLAEMTQKTKEFSNL-EIIIKELRAENDQLNDELMNDQAELEEKDAEIQ 205 Query: 642 DKLADISQLQSDQVCSEIKSVH-LEEQIDA-LSASKKELALVIENLKLDKE-QLYGTIKD 698 + + + K++ L++QI A SK+ AL + + DK+ Q Y + Sbjct: 206 ELKEQNEGAYKMKYETATKTIELLQKQISASQEISKENDALKSKLAEKDKQLQNYNDMNS 265 Query: 699 LENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQ 758 L ++ + + KL I ++ D + EK +I L +I EE + +G Sbjct: 266 LIKEQREQIEKLSKNIDDSSDFAEN-EKKYQNEIQNLKKQI--EELQENDNAWGDIDDTD 322 Query: 759 ERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTI 818 E EN++ E+ K++ + +E + ++ K S LQE +K+ + + I Sbjct: 323 EIKQENENLKKEIENLKNQNKEIGNLQLQIEKLKDIIKEKESDNESLLQELEKSENNFEI 382 Query: 819 QEDELVNRLAVLMDHDRVVEKQLLEIEHE------NKELQKKNQILLEENQNLQISLSDM 872 ++ + N+ L + +++ + E+E N E+++ L +E NL+ ++ Sbjct: 383 EKIKKENQ--NLQTKVKEMQETIDELESNAWNDDGNDEIKQNLDKLKQEINNLKKENENL 440 Query: 873 QQHYNALVEKA-NRTDLAESESTKYQTQ-LRDLESNLKRITHEH---------QTLIVQK 921 Q+ E A N + E E K + L+ NLK+I E + I + Sbjct: 441 QKQVEENEENAWNDGNNDEIEEIKQNLEKLQKENENLKKINEEKSNDDEINKLKQEISEL 500 Query: 922 KKEIEDLEIEF-----NTQIESAIRDKKVLNEKYEKNI-EYVTQLEAQLQEYKNNIEN-L 974 KKE E+L+ N + I + K NEK ++NI E Q+E + N EN L Sbjct: 501 KKENEELQENLWNENENEDNQEEISNLKKENEKLKQNIKELQKQIETNEENLWNENENDL 560 Query: 975 NMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDE---EIIALNQK 1031 V EL + ++ DK ++++ + E+ EI+ L + + DE E L Q+ Sbjct: 561 KQKVTEL-ESEVKNSDK-LKEENNKLKKENEELKKEIDDLTENVWKDDEDNQETEKLKQE 618 Query: 1032 INNAQVSYMSMVSDYESKL-----AQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVR 1086 INN + + + + +T + + ++++++ + ++ D+++ NE+L+ L+ Sbjct: 619 INNLKKENEELKKEMDELQESTWNESYTEESDELKQKLKELEQKYKDTEKSNEDLKKLLE 678 Query: 1087 EQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQE 1146 + D+ KE ++ E I + + E + ++ LK +E Sbjct: 679 QVDNLQKESEKINQDLEKQIEENQENSDVDENEILKQKVTELESEVKEKEKLNEELK-KE 737 Query: 1147 EEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQ- 1205 E+ +E LQE +A TE +E K LE N L N + +N LK KL + Sbjct: 738 NEDLKKEVENLQE-NAWNETENEEIKEK---LEKENEILQKQVEENNKTLNDLKQKLSES 793 Query: 1206 ------LNTENDNLLSTVAELRS--SISSAVDQRGFEIAELWKQHLAQREADFQKTEHEL 1257 N+END L V E+ S IS+ + ++ Q+L + E + K E Sbjct: 794 ENEKSVKNSENDKLKQKVTEIESDFKISNEKSSNLQQKLDVLSQNLEKLEKE-MKISSEK 852 Query: 1258 RVQLSAFESKYEQLLDSVQSSTQEETNKIVT-MEQVTSLQNKLQDKEEHLRNLQEKYADV 1316 +L S + S+Q + KI + +++ + L+N+L E +NL+ ++ Sbjct: 853 NQKLQKENSDLQNQFTSLQKQNSDNQLKITSLLKEKSELENQL--NENSTQNLESNSSE- 909 Query: 1317 INQIEILRSEI--EDEKVAFXXXXXXXXXXXXXXXXDL-RTENQSYKQMQEQSILNINEE 1373 +I L+ +I ++EK+ DL ++ + +++ I N+ E Sbjct: 910 -KEIRDLKEKITKQNEKI------KELEEEVKKGYQDLWGADSDDDSKEKDEEIKNLKLE 962 Query: 1374 NAQLKKSS-XXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRND 1432 ++ K+ + E K+ ++ L+ KD EI + E + + D Sbjct: 963 IEKINKNHLEKIGIVEKEKKNEIEKRENKIKKMRIDLQKKDEEINKLNKEIS---QNKKD 1019 Query: 1433 EFENVR-------QQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERV 1485 E+ V L + +RI+ EK+ E+ ++ K+ + E E + + Sbjct: 1020 EWSTVTFGDDEEISSLKKENERIKQEITEKQKEIEEIQQKLSKFTKENEEKSSEISLLKK 1079 Query: 1486 KLIEELNVKITESVSLNKQVAELN---KALEEEVAKTNEMQTALENQEIEIVTLNDEITN 1542 + E+L+V E+ L +++ E N K EE K + + + EI L E Sbjct: 1080 ENEEKLSVLEKENEELKQRIEEFNSFKKENEENKQKIYNLGEETKKKLNEISVLKKENEE 1139 Query: 1543 LQNMVRASSSKI-QKHVSF---ASDTKQGRDEQLDNTMNKE 1579 L+ + + ++ QK V F S++K+ +E+L + + KE Sbjct: 1140 LKQKLNEINEEMKQKIVDFNEKFSNSKKENEEKL-SVLKKE 1179 Score = 136 bits (330), Expect = 4e-30 Identities = 212/975 (21%), Positives = 429/975 (44%), Gaps = 104/975 (10%) Query: 144 VTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXX 203 VT L + +KEK+ L+ + + ++ + +LQE + + E K K Sbjct: 717 VTELESEVKEKEKLNEELKKENEDLKKEVENLQENAWNETENEEIKEK-LEKENEILQKQ 775 Query: 204 XXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAA 263 D KQ++++ EN +++ D+ ++ + +IES D +IS+ + +N Sbjct: 776 VEENNKTLNDLKQKLSE-SENEKSVKNSENDKLKQKVTEIES-DFKISNEKSSN------ 827 Query: 264 RFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTE 323 + + L+Q LE+ L K++ + + T ++++ S +T Sbjct: 828 ---LQQKLDVLSQNLEKLEKEMKISSEKNQKLQKENSDLQ-NQFTSLQKQNSDNQLKITS 883 Query: 324 LTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMK 383 L K+ ELEN+L T++ +S K+ L + + +N K Sbjct: 884 LLKE--------------KSELENQLNENSTQNLESNSSEKEIRDLKEKITKQNEKIKEL 929 Query: 384 SPWSQLSSETL---NQDTDKKINKNEIAKLEMVIQSLNKD------LVDKE--YVISEKD 432 + + L + D D K EI L++ I+ +NK+ +V+KE I +++ Sbjct: 930 EEEVKKGYQDLWGADSDDDSKEKDEEIKNLKLEIEKINKNHLEKIGIVEKEKKNEIEKRE 989 Query: 433 TXXXXXXXXXXGKDTLIAQLQLEHQQHMEGP-SLIHVGTNTEDVNEIAKVQEQLKQELND 491 KD I +L E Q+ + S + G + E+++ + K E++KQE+ + Sbjct: 990 NKIKKMRIDLQKKDEEINKLNKEISQNKKDEWSTVTFG-DDEEISSLKKENERIKQEITE 1048 Query: 492 EIKDV-NVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKV 550 + K++ ++ + K E+ + + N+ + V +LKQ + ++F K Sbjct: 1049 KQKEIEEIQQKLSKFTKENEEKSSEISLLKKENEEKLSVLEKENEELKQRIEEFNSFKKE 1108 Query: 551 SDSNKE-IVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLA 609 ++ NK+ I L EE +++ L++E L+ L + I ++ +K+++ Sbjct: 1109 NEENKQKIYNLGEETKKKLNEISVLKKENEELKQKLNE------INEEMKQKIVDFN--- 1159 Query: 610 ETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQID 669 + K + ++L +L+++ D ++ KL + + + SE L D Sbjct: 1160 -------EKFSNSKKENEEKLSVLKKENDNLKQKLNEFNSFMKE---SEENKQRLN---D 1206 Query: 670 ALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKL---EK 726 +KK+L++ LK + E++ I DL + +++ +L I+EN + KL E Sbjct: 1207 LGEETKKKLSI----LKKENEEMKQNISDLMKENKELNERLSKSIKENEENKKKLNENEL 1262 Query: 727 MSAEKISE--LLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEES 784 ++I E LL K N E + K+ I+ +++++ I N++ E K + EE Sbjct: 1263 NFKQEIEENSLLKKENEENKQKLNE---INQEMKKKLNEISNLKRENEDLKRSLNGNEEI 1319 Query: 785 IAVMEDRRYSLERKADQLGSYLQE-KQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLE 843 I M + + ++ D + +E KQ + + ++L N ++ + + ++KQ+ E Sbjct: 1320 IEEMNE----INKENDSIKKENKEMKQNLIPKLQKENEKLNNEISQIQIENEKLKKQIEE 1375 Query: 844 IEHENKELQKKNQILLEENQNLQISLSDMQQ--HYNALVEKAN-RTDLAESESTKYQTQL 900 ++ + E+ + L +EN++L+ SL+ Q+ N ++K N + + E K Sbjct: 1376 MKQISNEISQ----LKQENEDLKRSLNGNQEINKENDDLKKENEKLNQKMEEMKKSLVDK 1431 Query: 901 RDLESNLKRITHEHQTLIV---QKKKEIEDLEIEF-NTQIE-SAIRDKKV-LNEKYEKNI 954 +L LK++ E++ L + QK+KE E + E QIE +D + LN Sbjct: 1432 SNLNELLKKLQKENEELSISLSQKQKENEKINEELTKKQIEIEKQKDLETNLNNSDANKD 1491 Query: 955 EYVTQLEAQLQEYKNNIENLNM-------NVEELNKMNLELIDKHVQKQQTQSPDYTEQY 1007 E + L+ + +E K N E L++ +V+ LN NL LI ++ QK+ T + TE+ Sbjct: 1492 EMIELLQNENEETKRNNEELSLLLEKYKHDVDSLNAKNLHLIKENEQKEITINNLNTEK- 1550 Query: 1008 INEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRV 1067 E+ K+N L+Q + I+ ++ +V + + + K+ + MQ + Sbjct: 1551 -KELGKINKQLEQ-SKSILESQKEYEEMKVKQVEKPKQINANDIKEKEKMNDCMMRMQYL 1608 Query: 1068 SKQLLDSKQHNEELQ 1082 L+ N Q Sbjct: 1609 QSALIQFFHQNTSTQ 1623 Score = 120 bits (288), Expect = 4e-25 Identities = 211/1029 (20%), Positives = 460/1029 (44%), Gaps = 110/1029 (10%) Query: 632 ILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSA--SKKELALVIENLKLDK 689 +L+QK + D +SQ+ + V + K LE+Q++ A S + ++ +N ++ + Sbjct: 15 LLKQKTARIRDLEKMLSQMNAPSVDNSSKIEELEQQLEDSKALISALQESVSQKNAEISR 74 Query: 690 EQLYGTIKDLENDKEDIMNKLQNYI----QENMDLTDKLEKMSAEKISELLAKINHEEQS 745 L + N D++ LQ I QE L ++L + + + N + Q Sbjct: 75 LSLISQ-SNARNQNSDLIASLQKKIAEQQQEIESLNNELWNDDPNESEKDIEIQNLKSQI 133 Query: 746 KIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSY 805 + T+ + ++ + S+L++ + ++++ R ++ D+L + Sbjct: 134 QKLTKNQPQVSPASNNAELDTLRSQLAEMTQKTKEFSNLEIIIKELRAENDQLNDELMND 193 Query: 806 LQEKQKAYSEYTIQEDELVNRLAVLMDHD------RVVEKQLLEIEHENKELQKKNQILL 859 E ++ +E IQE + N A M ++ +++KQ+ + +KE L Sbjct: 194 QAELEEKDAE--IQELKEQNEGAYKMKYETATKTIELLQKQISASQEISKENDALKSKLA 251 Query: 860 EENQNLQ--ISLSDMQQHYNALVEKANR-----TDLAESESTKYQTQLRDLESNLKRI-- 910 E+++ LQ ++ + + +EK ++ +D AE+E KYQ ++++L+ ++ + Sbjct: 252 EKDKQLQNYNDMNSLIKEQREQIEKLSKNIDDSSDFAENEK-KYQNEIQNLKKQIEELQE 310 Query: 911 ----------THEHQTLIVQKKKEIEDLEIE----FNTQIESAIRDKKVLNEKYEKNIEY 956 T E + KKEIE+L+ + N Q++ + K ++ EK N Sbjct: 311 NDNAWGDIDDTDEIKQENENLKKEIENLKNQNKEIGNLQLQIE-KLKDIIKEKESDNESL 369 Query: 957 VTQLEA-----QLQEYKNNIENLNMNVEELNKMNLEL----IDKHVQKQQTQSPDYTEQY 1007 + +LE ++++ K +NL V+E+ + EL + + Q+ D +Q Sbjct: 370 LQELEKSENNFEIEKIKKENQNLQTKVKEMQETIDELESNAWNDDGNDEIKQNLDKLKQE 429 Query: 1008 INEINKLNA-LLKQKDE-EIIALNQKINNAQVSYMSMVSDYESKLAQFTTKL---ENMEE 1062 IN + K N L KQ +E E A N NN ++ + + K + K+ ++ ++ Sbjct: 430 INNLKKENENLQKQVEENEENAWNDG-NNDEIEEIKQNLEKLQKENENLKKINEEKSNDD 488 Query: 1063 EMQRVSKQLLDSKQHNEELQILV------REQDDQIKELKETKLTFEMNIPKTEGMIISS 1116 E+ ++ +++ + K+ NEELQ + + ++I LK+ + NI + + I ++ Sbjct: 489 EINKLKQEISELKKENEELQENLWNENENEDNQEEISNLKKENEKLKQNIKELQKQIETN 548 Query: 1117 TIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKII 1176 +++ N++ KV E E ++ L+E++ KL E +E +I Sbjct: 549 EENLWNENENDLKQ------------KVTELESEVKNSDKLKEENNKLKKENEELKKEID 596 Query: 1177 QLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSI-SSAVDQRGFEI 1235 L TE D + ++ +LK ++ L EN+ L + EL+ S + + + E+ Sbjct: 597 DL----TENVWKDDEDNQETEKLKQEINNLKKENEELKKEMDELQESTWNESYTEESDEL 652 Query: 1236 AELWKQHLAQREADFQKTEHELRVQLSAFES------KYEQLLDSVQSSTQEETN---KI 1286 + K+ L Q+ D +K+ +L+ L ++ K Q L+ QE ++ Sbjct: 653 KQKLKE-LEQKYKDTEKSNEDLKKLLEQVDNLQKESEKINQDLEKQIEENQENSDVDENE 711 Query: 1287 VTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILR----SEIEDEKVAFXXXXXXXX 1342 + ++VT L++++++KE+ L+++ D+ ++E L+ +E E+E++ Sbjct: 712 ILKQKVTELESEVKEKEKLNEELKKENEDLKKEVENLQENAWNETENEEIKEKLEKENEI 771 Query: 1343 XXXXXXXXDLRTENQSYKQMQEQSILNI-NEENAQLKKSSXXXXXXXXXXXXRVNDAEAK 1401 + + K + ++ ++ N EN +LK+ + ++ + K Sbjct: 772 LQKQVEENNKTLNDLKQKLSESENEKSVKNSENDKLKQKVTEIESDFKISNEKSSNLQQK 831 Query: 1402 VLELTHQLELKDSEI---YQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESE 1458 + L+ LE + E+ +K + + ++F ++++Q + + +I L EK Sbjct: 832 LDVLSQNLEKLEKEMKISSEKNQKLQKENSDLQNQFTSLQKQNSDNQLKITSLLKEKSE- 890 Query: 1459 LAILRLKMHENA-NHYETMQKESEIERVK-LIEELNVKITE-SVSLNKQVAELNKALEEE 1515 L +++EN+ + E+ E EI +K I + N KI E + K +L A ++ Sbjct: 891 ---LENQLNENSTQNLESNSSEKEIRDLKEKITKQNEKIKELEEEVKKGYQDLWGADSDD 947 Query: 1516 VAKTNEMQTALENQEIEIVTLN-DEITNLQNMVRASSSKIQKHVSFASDTK---QGRDEQ 1571 +K E ++N ++EI +N + + + + + ++I+K + + Q +DE+ Sbjct: 948 DSK--EKDEEIKNLKLEIEKINKNHLEKIGIVEKEKKNEIEKRENKIKKMRIDLQKKDEE 1005 Query: 1572 LDNTMNKEL 1580 + N +NKE+ Sbjct: 1006 I-NKLNKEI 1013 >UniRef50_A7TQ63 Cluster: Putative uncharacterized protein; n=1; Vanderwaltozyma polyspora DSM 70294|Rep: Putative uncharacterized protein - Vanderwaltozyma polyspora DSM 70294 Length = 2546 Score = 197 bits (481), Expect = 2e-48 Identities = 296/1474 (20%), Positives = 637/1474 (43%), Gaps = 139/1474 (9%) Query: 164 KMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXX---XXXXXXXXXXEDTKQQMTK 220 +++ E I DLQ + K+ ++ NK + +++ Sbjct: 878 ELESTEKQITDLQSNLESKNTELDNLNKEKSGLMKELTEWKAKFKSHDALVPKLTEKLKS 937 Query: 221 MQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQ 280 + ++ ++ E + +L++ ++K +SSL E+ L+ + +I E SKL ++ + Sbjct: 938 LANSYKELQTERDNYSSQLIEINKNKTSELSSLSESISNLKIEKDKILDEKSKLINKVSE 997 Query: 281 XXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKI-ELLEHLNCQIR 339 + I +C+ E +EK L + EL + E L+ L Q Sbjct: 998 ---------------LESQITENCKIFEEEKEKLILSKDELEELVIDLNEQLKELETQKE 1042 Query: 340 QTNK---ELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQ 396 T+K EL +A + T+ K S + L+ + +N + +S S L ++ Sbjct: 1043 TTSKNADELNKSIANLNTQLKQKDSKLIELEELV--EVTKNNLNDSESQVSNLIAKISEL 1100 Query: 397 DTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEH 456 D + K K E+ KLE I + + T I L+ E+ Sbjct: 1101 DEENKSVKLEVEKLENEITEIKNSHKSAQKETDTLQTKLDETELLLQSSKEEILSLKNEY 1160 Query: 457 QQHMEGPSLIHVG--TNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQ 514 + + ++E + E+ K L QE + I N K L E+ EE+ Sbjct: 1161 SSTLSDKENLENSEKKSSEKIEELEKNFSNL-QEQFENITAEN-KSLKEECSGTEEKFKD 1218 Query: 515 LNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSK-VSDSNKEIVRLTEELHHLSQKVAE 573 +N+++D + I S+ K KL + ID+ K +S+ N+++ ++E++ + + Sbjct: 1219 VNEKLDQYGET-ISSLSDEKDKLNGI---IDDKEKIISNLNEKLESISEDIDIIEKAKNL 1274 Query: 574 LEEEKGNLQLHLVDYDSGRMIESDVYKKM-IEMENLAETRL-KAISL--LESQKFDLVQE 629 LEE+ + L D ++G +Y + IE E L +T K+ +L LE++ L + Sbjct: 1275 LEEKLATMTSELNDSENGSSELRSLYDSLKIEFEELQKTNSDKSANLKELENKHTSLTET 1334 Query: 630 LHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDK 689 IL + ++E + D +++ D E + L + + L K +L +++E Sbjct: 1335 QEILLEDKKKMESSINDYVKIKDD---LEKEKEDLLNKYNVLEDKKDKLEIILEENNSSI 1391 Query: 690 EQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQT 749 + L +I L+ + E N++ + ++ M+ ++ K A + + ++++ EE +K++ Sbjct: 1392 KVLEHSIDALKKENEIYKNEIHD-MKLQMESSNSEYKNKAGEQEKKISRLK-EECNKLKN 1449 Query: 750 QFGIDAKIQERDLYIENI----ESELSKYKSRICRLEESIAVMEDRRYSLER-KADQLGS 804 + + KI++ ++ +N+ ++E +++ +I L++ I +E + E+ +Q + Sbjct: 1450 SY--EEKIEKLEVESKNLSLGHDTEKKQFEDKITSLKQEIISIEKSKKQDEKVLKNQKNT 1507 Query: 805 YLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQN 864 +E ++ ++T E+E + +L + V K+ L+IE +L + + Sbjct: 1508 LQKELEELKDQFTNSENEYIKKLDNFQNEINSVRKEKLDIE----------AVLNSKIET 1557 Query: 865 LQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKE 924 L+ LS ++ + ++EK+N+ L + E Q L L + +E TL + E Sbjct: 1558 LKADLSKSEEK-SLILEKSNKEHLIKME--VIQKSLEKQNKELDILGNEKDTLTMNLNNE 1614 Query: 925 IEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKM 984 I+ L+ E N++++ + L+ +L N+E++ + ++L + Sbjct: 1615 IKGLKEEINSKVDQ------------------IGNLKTELNTVSENMEDIQVRYDQLKEE 1656 Query: 985 NLELIDKHVQKQQTQSPDYTEQYINEIN----KLNALLKQKDEEIIALNQKINNAQVSYM 1040 E+ DK ++ ++ +++ I+++N L A + KDEE L ++ ++S Sbjct: 1657 KSEISDKLIESEEKLKENFSS--ISDLNSSVISLEASIISKDEEYTLLKKEFEEVKISKQ 1714 Query: 1041 SMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSK--QHNEELQILVREQDDQIKELKET 1098 + + + L +++ E +++ + + LDSK + ++E ++L D+ +E E Sbjct: 1715 ELDNQKDKLLEEYSIMKRTNESKLKDLRNE-LDSKIIKFDKERKLLNEGSDNIAQEYSEK 1773 Query: 1099 KLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQ 1158 + E + + I S + +S+ N+ L+ + EE + S L Sbjct: 1774 VTSLEEELRNQK--IYSD--DKISELEENIKSKNNALTEKSNLLQ-KRLEEIKELESTLS 1828 Query: 1159 EQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVA 1218 + A L ++ K + E + EL+ + N++K K+E++ + ++L++ + Sbjct: 1829 KYKADLEATMKNSDLKNDEFENVCKELSVKE-------NEIK-KIEEILSSKEDLIAEIE 1880 Query: 1219 ELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSS 1278 + ++ ++++ L ++E+ + + ++ VQ + K + D++Q Sbjct: 1881 SQKDNLKDELNEKSL--------LLDKKESQLEAFQEDVEVQKENLQKKITE-YDNLQKL 1931 Query: 1279 TQEETNKIVTME-QVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXX 1337 + K+V E Q+ L+ KL+ HL+ + KY E L E + K Sbjct: 1932 MSLDNKKLVKCEKQIEDLELKLESSSNHLKEQEGKY-------EKLEFESGENK----KL 1980 Query: 1338 XXXXXXXXXXXXXDLRTENQSYKQMQEQ-SILNINEENAQLKKSSXXXXXXXXXXXXRVN 1396 D+ +++ ++ S L N EN +L + Sbjct: 1981 ISEKDELIQTLQLDISNNKDEIQKLSDKISTLQNNSENTELTLEEKEKMVDELNSKLQEK 2040 Query: 1397 DAEAKVLEL-THQL-ELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYE 1454 +A+ + LEL ++L E D E+ + + E I DE +Q++ E + +I+D E Sbjct: 2041 EAQVETLELDLNKLKETLDKEL-ESSSELQIAHDNLRDENIIQKQKITELKVKIDD--SE 2097 Query: 1455 KESELAILRLK-MHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALE 1513 K+S++ I +K M EN I+ K+ E+L+ K +E LNK++AE K E Sbjct: 2098 KDSQVIIDNMKEMEENIMDLRNDLSSKTIQIEKVNEDLSSKNSEIEQLNKKLAE--KCAE 2155 Query: 1514 EEVAKTNEMQTA--LENQEIEIVTLNDEITNLQNMVRASSSKIQKHVS---FASDTKQGR 1568 + K+ + ++ E+++ ++ L+DEI L+ + + ++K S A++T Sbjct: 2156 YDSIKSELVASSKLSESEKNDMKQLSDEINELKEQLELKNENLKKVTSDLQIANNTSDKY 2215 Query: 1569 DEQLD--NTMNKELLDAVPRAELDLAMYMLHQRD 1600 +++L N +E+ +P + L + + D Sbjct: 2216 NDELKVANNTIREIESKIPNLQKQLDLKEIEYND 2249 Score = 173 bits (422), Expect = 3e-41 Identities = 281/1434 (19%), Positives = 610/1434 (42%), Gaps = 120/1434 (8%) Query: 224 NFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLL--EAARFEISLEHSKLAQELEQX 281 N IA +E +E + + ++E + I+ ++ ++K E + L+ ++L + + Sbjct: 1092 NLIAKISELDEENKSVKLEVEKLENEITEIKNSHKSAQKETDTLQTKLDETELLLQSSKE 1151 Query: 282 XXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTE----LTKKIELLEHLNCQ 337 K+++E S ++ +E E+ +N+ E +T + + L+ Sbjct: 1152 EILSLKNEYSSTLSDKENLENSEKKSSEKIEELEKNFSNLQEQFENITAENKSLKEECSG 1211 Query: 338 IRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQD 397 + K++ KL G ++S K + +I K S + +S + + Sbjct: 1212 TEEKFKDVNEKLDQYGETISSLSDEKDKLNGIIDDKE--KIISNLNEKLESISEDIDIIE 1269 Query: 398 TDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQ 457 K + + ++A + + + + K + +L+ +H Sbjct: 1270 KAKNLLEEKLATMTSELNDSENGSSELRSLYDSLKIEFEELQKTNSDKSANLKELENKHT 1329 Query: 458 QHMEGPSLIHVGTNTED--VNEIAKVQEQLKQELNDEIKDVNV----KDLIEK-LKSAEE 510 E ++ + +N+ K+++ L++E D + NV KD +E L+ Sbjct: 1330 SLTETQEILLEDKKKMESSINDYVKIKDDLEKEKEDLLNKYNVLEDKKDKLEIILEENNS 1389 Query: 511 QITQLNDEIDAANK-NMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLS- 568 I L IDA K N I H +KL+ + +K + K+I RL EE + L Sbjct: 1390 SIKVLEHSIDALKKENEIYKNEIHDMKLQMESSNSEYKNKAGEQEKKISRLKEECNKLKN 1449 Query: 569 ---QKVAELEEEKGNLQLHLVDYDSGR-MIESDVYKKMIEMENLAETRLKAISLLESQKF 624 +K+ +LE E NL L +D+ + E + E+ ++ +++ + +L++QK Sbjct: 1450 SYEEKIEKLEVESKNLSL---GHDTEKKQFEDKITSLKQEIISIEKSKKQDEKVLKNQKN 1506 Query: 625 DLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEE-QIDALSASKKELALVIE 683 L +EL L+ ++ E++ I +L + Q +EI SV E+ I+A+ SK IE Sbjct: 1507 TLQKELEELKDQFTNSENEY--IKKLDNFQ--NEINSVRKEKLDIEAVLNSK------IE 1556 Query: 684 NLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDK-LEKMSAEKISELLAKINHE 742 LK D + LE ++ + K++ IQ++++ +K L+ + EK L +N+E Sbjct: 1557 TLKADLSKSEEKSLILEKSNKEHLIKME-VIQKSLEKQNKELDILGNEK-DTLTMNLNNE 1614 Query: 743 EQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQL 802 + G+ +I + I N+++EL+ + ++ +++ + + K + Sbjct: 1615 IK-------GLKEEINSKVDQIGNLKTELNTVSENMEDIQVRYDQLKEEKSEISDKLIES 1667 Query: 803 GSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEEN 862 L+E + S+ L + + +++K+ E++ +EL + LLEE Sbjct: 1668 EEKLKENFSSISDLNSSVISLEASIISKDEEYTLLKKEFEEVKISKQELDNQKDKLLEEY 1727 Query: 863 QNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKK 922 ++ + + + L + N D S+ K+ + + L I E+ + + Sbjct: 1728 SIMK------RTNESKLKDLRNELD---SKIIKFDKERKLLNEGSDNIAQEYSEKVTSLE 1778 Query: 923 KEIEDLEIEFN---TQIESAIRDKK-VLNEK---YEKNIEYVTQLEAQLQEYKNNIE--- 972 +E+ + +I + +++E I+ K L EK +K +E + +LE+ L +YK ++E Sbjct: 1779 EELRNQKIYSDDKISELEENIKSKNNALTEKSNLLQKRLEEIKELESTLSKYKADLEATM 1838 Query: 973 -NLNMNVEELNKMNLELIDKHVQ-KQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQ 1030 N ++ +E + EL K + K+ + E I EI LK + E L Sbjct: 1839 KNSDLKNDEFENVCKELSVKENEIKKIEEILSSKEDLIAEIESQKDNLKDELNEKSLLLD 1898 Query: 1031 KINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDD 1090 K + ++ V + L + T+ +N+++ M +K+L+ ++ E+L++ + + Sbjct: 1899 KKESQLEAFQEDVEVQKENLQKKITEYDNLQKLMSLDNKKLVKCEKQIEDLELKLESSSN 1958 Query: 1091 QIKEL--KETKLTFEMNIPKTEGMIISSTIEPMS-DDANNVDX--------XXXXXXXXX 1139 +KE K KL FE K I+ + D +NN D Sbjct: 1959 HLKEQEGKYEKLEFESGENKKLISEKDELIQTLQLDISNNKDEIQKLSDKISTLQNNSEN 2018 Query: 1140 XXLKVQEEEEFIQE-RSVLQEQSAKLNT------ELQECYTKIIQ----LETLNTELTGH 1188 L ++E+E+ + E S LQE+ A++ T +L+E K ++ L+ + L Sbjct: 2019 TELTLEEKEKMVDELNSKLQEKEAQVETLELDLNKLKETLDKELESSSELQIAHDNLRDE 2078 Query: 1189 DVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWK--QHLAQR 1246 +++ +++I +LK K++ ++ ++ + E+ +I + + ++ K + L+ + Sbjct: 2079 NIIQKQKITELKVKIDDSEKDSQVIIDNMKEMEENIMDLRNDLSSKTIQIEKVNEDLSSK 2138 Query: 1247 EADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHL 1306 ++ ++ +L + + ++S +L+ S + S E+ + +++ L+ +L+ K E+L Sbjct: 2139 NSEIEQLNKKLAEKCAEYDSIKSELVASSKLSESEKNDMKQLSDEINELKEQLELKNENL 2198 Query: 1307 R----------NLQEKYADVI----NQIEILRSEIED-EKVAFXXXXXXXXXXXXXXXXD 1351 + N +KY D + N I + S+I + +K D Sbjct: 2199 KKVTSDLQIANNTSDKYNDELKVANNTIREIESKIPNLQKQLDLKEIEYNDTLSSKKDLD 2258 Query: 1352 LRTENQSYK-QMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLE 1410 + +N S + ++ + + ++ +E L+K + D + E Sbjct: 2259 KKLDNFSKESEILSKEVKSLKKEKLDLEKEKNDLIVELDKYKNDIIDLNNTLKENEKNGS 2318 Query: 1411 LKDSEIY---QKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMH 1467 ++EI K Y + ++Q N+E + + +D +SE+ L K+ Sbjct: 2319 EVETEIIGLKDKIEFYKLNVSQLNEEKGKLESDIKTLVGERDDKLKSSQSEIIELTNKL- 2377 Query: 1468 ENANHYETMQKESEIERVKLIEELNVKITESVS-LNKQVAELNKALEEEVAKTNEMQTAL 1526 E+ +ES++E L +L+ +I +S+ N+ V NK E++ M L Sbjct: 2378 ESFKDISVAYEESKVESDGLKNKLS-EIEKSLEESNENVDSANK----EISDLKVMNDKL 2432 Query: 1527 ENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKEL 1580 ++ +E L D+ L+N ++ KIQ ++ + + + E+ ++ +E+ Sbjct: 2433 QSHNLE---LEDKFQQLKNDTTETNRKIQ-DINKLKEEESSKAEEKIRSLTEEI 2482 Score = 171 bits (417), Expect = 1e-40 Identities = 279/1336 (20%), Positives = 565/1336 (42%), Gaps = 125/1336 (9%) Query: 305 EEKTEIEEKGSLEIANMTELTKKI-ELLEHLNCQIRQTNKELENKLATMGTESKAVSSPS 363 + K+++E K L I + K++ E ++ + + NKEL N + E + + Sbjct: 800 QNKSDLE-KCKLNIEKLENELKEVKERKDNAENGVNKMNKELSN----LSKEKEQLRIEQ 854 Query: 364 KKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKIN---KN-EIAKLEMVIQSLNK 419 K I + SK+K ++Q T Q TD + N KN E+ L L K Sbjct: 855 GKLEKKIQEQISVYEDSKIK--FNQELESTEKQITDLQSNLESKNTELDNLNKEKSGLMK 912 Query: 420 DLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTN-TEDVNEI 478 +L + + D +LQ E + LI + N T +++ + Sbjct: 913 ELTEWKAKFKSHDALVPKLTEKLKSLANSYKELQTERDNYSS--QLIEINKNKTSELSSL 970 Query: 479 AKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLK 538 ++ LK E D+I D K LI K+ E QIT+ K+ K KL Sbjct: 971 SESISNLKIE-KDKILDEKSK-LINKVSELESQITE-----------NCKIFEEEKEKLI 1017 Query: 539 QMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDV 598 + ++ V D N+++ L + S+ EL + NL L DS Sbjct: 1018 LSKDELEEL--VIDLNEQLKELETQKETTSKNADELNKSIANLNTQLKQKDS-------- 1067 Query: 599 YKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSE 658 K+IE+E L E ++ ESQ +L+ ++ L ++ V+ ++ +L+++ +E Sbjct: 1068 --KLIELEELVEVTKNNLNDSESQVSNLIAKISELDEENKSVK---LEVEKLENE--ITE 1120 Query: 659 IKSVH--LEEQIDALSASKKELALVIENLKLD----KEQLYGTIKD---LENDKEDIMNK 709 IK+ H +++ D L E L++++ K + K + T+ D LEN ++ K Sbjct: 1121 IKNSHKSAQKETDTLQTKLDETELLLQSSKEEILSLKNEYSSTLSDKENLENSEKKSSEK 1180 Query: 710 LQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQT----QFG--IDAKIQERDLY 763 ++ + +L ++ E ++AE S EE+ K Q+G I + E+D Sbjct: 1181 IEELEKNFSNLQEQFENITAENKSLKEECSGTEEKFKDVNEKLDQYGETISSLSDEKDKL 1240 Query: 764 ---IENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQE 820 I++ E +S ++ + E I ++E + LE K + S L + + SE Sbjct: 1241 NGIIDDKEKIISNLNEKLESISEDIDIIEKAKNLLEEKLATMTSELNDSENGSSELRSLY 1300 Query: 821 DELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALV 880 D L L + L E+E+++ L + +ILLE+ + ++ S++D + + L Sbjct: 1301 DSLKIEFEELQKTNSDKSANLKELENKHTSLTETQEILLEDKKKMESSINDYVKIKDDLE 1360 Query: 881 EK----ANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEI-EFNTQ 935 ++ N+ ++ E + K + L + S++K + EH ++K+ EI EI + Q Sbjct: 1361 KEKEDLLNKYNVLEDKKDKLEIILEENNSSIKVL--EHSIDALKKENEIYKNEIHDMKLQ 1418 Query: 936 IESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQK 995 +ES+ + K + EK I ++L+ + + KN+ E + E+ NL L +K Sbjct: 1419 MESSNSEYKNKAGEQEKKI---SRLKEECNKLKNSYEE-KIEKLEVESKNLSLGHDTEKK 1474 Query: 996 QQTQSPDYTEQYINEINKL-----NALLKQKD---EEIIALNQKINNAQVSYMSMVSDYE 1047 Q +Q I I K L QK+ +E+ L + N++ Y+ + +++ Sbjct: 1475 QFEDKITSLKQEIISIEKSKKQDEKVLKNQKNTLQKELEELKDQFTNSENEYIKKLDNFQ 1534 Query: 1048 SKL-----------AQFTTKLENMEEEMQRVSKQLL----DSKQHNEELQILVREQDDQI 1092 +++ A +K+E ++ ++ + ++ L +K+H +++++ + + Q Sbjct: 1535 NEINSVRKEKLDIEAVLNSKIETLKADLSKSEEKSLILEKSNKEHLIKMEVIQKSLEKQN 1594 Query: 1093 KELK---ETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEE 1149 KEL K T MN+ E + I D N+ ++V+ ++ Sbjct: 1595 KELDILGNEKDTLTMNL-NNEIKGLKEEINSKVDQIGNLKTELNTVSENMEDIQVR-YDQ 1652 Query: 1150 FIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTE 1209 +E+S + ++ + +L+E ++ I L + L + E+ LK + E++ Sbjct: 1653 LKEEKSEISDKLIESEEKLKENFSSISDLNSSVISLEASIISKDEEYTLLKKEFEEVKIS 1712 Query: 1210 NDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYE 1269 L + +L S ++ +L + L + F K L +Y Sbjct: 1713 KQELDNQKDKLLEEYSIMKRTNESKLKDL-RNELDSKIIKFDKERKLLNEGSDNIAQEYS 1771 Query: 1270 QLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHL---RNLQEKYADVINQIEILRSE 1326 + + S++ + + KI + ++++ L+ ++ K L NL +K + I ++E S+ Sbjct: 1772 EKVTSLEEELRNQ--KIYSDDKISELEENIKSKNNALTEKSNLLQKRLEEIKELESTLSK 1829 Query: 1327 IEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEE-NAQLKKSSXXXX 1385 + + A +L + K+++E IL+ E+ A+++ Sbjct: 1830 YKADLEATMKNSDLKNDEFENVCKELSVKENEIKKIEE--ILSSKEDLIAEIESQKDNLK 1887 Query: 1386 XXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYE 1445 ++ E+++ +E++ + +K EY Q+ +N ++LV+ E Sbjct: 1888 DELNEKSLLLDKKESQLEAFQEDVEVQKENLQKKITEY--DNLQKLMSLDN--KKLVKCE 1943 Query: 1446 KRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKI-TESVSLNKQ 1504 K+IEDL + ES L+ E YE ++ ES E KLI E + I T + ++ Sbjct: 1944 KQIEDLELKLESSSNHLK----EQEGKYEKLEFESG-ENKKLISEKDELIQTLQLDISNN 1998 Query: 1505 VAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDT 1564 E+ K + K + +Q EN E+ + + L + ++ ++++ + Sbjct: 1999 KDEIQKLSD----KISTLQNNSENTELTLEEKEKMVDELNSKLQEKEAQVETLELDLNKL 2054 Query: 1565 KQGRDEQLDNTMNKEL 1580 K+ D++L+++ ++ Sbjct: 2055 KETLDKELESSSELQI 2070 Score = 169 bits (411), Expect = 5e-40 Identities = 327/1541 (21%), Positives = 666/1541 (43%), Gaps = 173/1541 (11%) Query: 90 ISESLANT---LKQKEILMEKIKQYKELSKRS---STTIVRXXXXXXXXXXXXXXXQLGD 143 +++S+AN LKQK+ + ++++ E++K + S + V + Sbjct: 1051 LNKSIANLNTQLKQKDSKLIELEELVEVTKNNLNDSESQVSNLIAKISELDEENKSVKLE 1110 Query: 144 VTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKI-NEKDQIIEAKNK--ATTXXXXXX 200 V L N I E N+ Q + ++T + + + + + K++I+ KN+ +T Sbjct: 1111 VEKLENEITEIKNSHKSAQKETDTLQTKLDETELLLQSSKEEILSLKNEYSSTLSDKENL 1170 Query: 201 XXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRL------LKDIESK----DVRI 250 E+ ++ + +QE F + AE K K+ KD+ K I Sbjct: 1171 ENSEKKSSEKIEELEKNFSNLQEQFENITAENKSLKEECSGTEEKFKDVNEKLDQYGETI 1230 Query: 251 SSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEI 310 SSL + L + S L ++LE L ++ + E + Sbjct: 1231 SSLSDEKDKLNGIIDDKEKIISNLNEKLESISEDIDIIEKAKNLL-EEKLATMTSELND- 1288 Query: 311 EEKGSLEIANMTELTK-KIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPL 369 E GS E+ ++ + K + E L+ N KELENK ++ TE++ + KK Sbjct: 1289 SENGSSELRSLYDSLKIEFEELQKTNSDKSANLKELENKHTSL-TETQEILLEDKK---- 1343 Query: 370 ISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVIS 429 +S N K+K + + LN+ + K+ KLE++++ N + E+ I Sbjct: 1344 -KMESSINDYVKIKDDLEKEKEDLLNKYNVLEDKKD---KLEIILEENNSSIKVLEHSID 1399 Query: 430 EKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQEL 489 + E++ + G + E+ N++ E+ ++L Sbjct: 1400 ALKKENEIYKNEIHDMKLQMESSNSEYK-NKAGEQEKKISRLKEECNKLKNSYEEKIEKL 1458 Query: 490 NDEIKDVNVKDLIEKLKSAEEQITQLNDEI---DAANKNMIKVKSNHKLKL-KQMQKTID 545 E K++++ EK K E++IT L EI + + K KV N K L K++++ D Sbjct: 1459 EVESKNLSLGHDTEK-KQFEDKITSLKQEIISIEKSKKQDEKVLKNQKNTLQKELEELKD 1517 Query: 546 NFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEM 605 F+ +S E ++ +L + ++ + +EK L + V +++D Sbjct: 1518 QFT---NSENEYIK---KLDNFQNEINSVRKEK--LDIEAVLNSKIETLKAD-------- 1561 Query: 606 ENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVC----SEIKS 661 L+++ K++ L +S K L++ + ++Q+ ++ ++K DI + D + +EIK Sbjct: 1562 --LSKSEEKSLILEKSNKEHLIK-MEVIQKSLEK-QNKELDILGNEKDTLTMNLNNEIKG 1617 Query: 662 V--HLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMD 719 + + ++D + K EL V EN++ D + Y +K+ +++ D + + + ++EN Sbjct: 1618 LKEEINSKVDQIGNLKTELNTVSENME-DIQVRYDQLKEEKSEISDKLIESEEKLKENFS 1676 Query: 720 LTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRIC 779 L + +++K EE + ++ +F + KI +++L +N + +L + S + Sbjct: 1677 SISDLNSSVISLEASIISK--DEEYTLLKKEFE-EVKISKQEL--DNQKDKLLEEYSIMK 1731 Query: 780 RLEESIAVMEDRRYSLERKA---DQLGSYLQEKQ----KAYSE-YTIQEDELVNRLAVLM 831 R ES ++D R L+ K D+ L E + YSE T E+EL N+ + Sbjct: 1732 RTNES--KLKDLRNELDSKIIKFDKERKLLNEGSDNIAQEYSEKVTSLEEELRNQK--IY 1787 Query: 832 DHDRVVEKQLLEIEHENKELQKKNQIL---LEENQNLQISLSDMQQHYNALVEKANRTDL 888 D++ E + I+ +N L +K+ +L LEE + L+ +LS + A ++ + DL Sbjct: 1788 SDDKISELEE-NIKSKNNALTEKSNLLQKRLEEIKELESTLSKYKADLEATMKNS---DL 1843 Query: 889 AESESTKYQTQLRDLESNLKRITH---EHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKV 945 E +L E+ +K+I + LI + + + ++L+ E N + S + DKK Sbjct: 1844 KNDEFENVCKELSVKENEIKKIEEILSSKEDLIAEIESQKDNLKDELNEK--SLLLDKKE 1901 Query: 946 LN-EKYEKNIEYVTQ-LEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQT----- 998 E +++++E + L+ ++ EY N + ++++ ++L K ++ D ++ + + Sbjct: 1902 SQLEAFQEDVEVQKENLQKKITEYDNLQKLMSLDNKKLVKCEKQIEDLELKLESSSNHLK 1961 Query: 999 -QSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKL 1057 Q Y E+ E + L+ +KDE I L I+N + + +SD S L + Sbjct: 1962 EQEGKY-EKLEFESGENKKLISEKDELIQTLQLDISNNK-DEIQKLSDKISTLQNNSENT 2019 Query: 1058 ENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISST 1117 E EE +++ +L +SK +E Q+ E D + +LKET L E+ +E I Sbjct: 2020 ELTLEEKEKMVDEL-NSKLQEKEAQVETLELD--LNKLKET-LDKELE-SSSELQIAHDN 2074 Query: 1118 IEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQ 1177 + D N + ++ + I ++E L +L +K IQ Sbjct: 2075 LR----DENIIQKQKITELKVKIDDSEKDSQVIIDNMKEMEENIMDLRNDLS---SKTIQ 2127 Query: 1178 LETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTV---AELRSSISSAVDQRGFE 1234 +E +N +L+ + +I QL KL + E D++ S + ++L S + + Q E Sbjct: 2128 IEKVNEDLSSKN----SEIEQLNKKLAEKCAEYDSIKSELVASSKLSESEKNDMKQLSDE 2183 Query: 1235 IAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTS 1294 I EL K+ L + + +K +L++ + + KY L ++ +E +KI +++ Sbjct: 2184 INEL-KEQLELKNENLKKVTSDLQIANNTSD-KYNDELKVANNTIREIESKIPNLQKQLD 2241 Query: 1295 LQN-KLQDKEEHLRNLQEKYADVINQIEILRSEIED---EKVAFXXXXXXXXXXXXXXXX 1350 L+ + D ++L +K + + EIL E++ EK+ Sbjct: 2242 LKEIEYNDTLSSKKDLDKKLDNFSKESEILSKEVKSLKKEKLDLEKEKNDLIVELDKYKN 2301 Query: 1351 DLRTENQSYKQMQEQSI-----------------LNINEENAQLKKSSXXXXXXXXXXXX 1393 D+ N + K+ ++ LN+++ N + K Sbjct: 2302 DIIDLNNTLKENEKNGSEVETEIIGLKDKIEFYKLNVSQLNEEKGKLESDIKTLVGERDD 2361 Query: 1394 RVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTY 1453 ++ ++++++ELT++LE + ++ + E + ++ +L E EK +E+ Sbjct: 2362 KLKSSQSEIIELTNKLE--------SFKDISVAYEESKVESDGLKNKLSEIEKSLEESNE 2413 Query: 1454 EKES-ELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKAL 1512 +S I LK+ + ++ E + +++K ++ N+++ ++NK Sbjct: 2414 NVDSANKEISDLKVMNDKLQSHNLELEDKFQQLK---------NDTTETNRKIQDINKLK 2464 Query: 1513 EEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSK 1553 EEE +K E +I +L +EI L+N + + SK Sbjct: 2465 EEESSKAEE----------KIRSLTEEIEKLKNDFKKNESK 2495 Score = 144 bits (348), Expect = 2e-32 Identities = 217/987 (21%), Positives = 431/987 (43%), Gaps = 99/987 (10%) Query: 637 YDEVEDKLADISQLQSDQV---CSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLY 693 +D ++ +A IS D++ CS++K L + + EL L +E L + Sbjct: 688 HDPEQESIAKISFETFDELQRECSKLKG-ELNDMFVSKGDVINELELKVEELSNKSKNSI 746 Query: 694 GTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGI 753 + ++N+ + + N + E ++ KL+++ E+ E L + E+ K++ Sbjct: 747 SDYESIKNEYDILKNNYEEKEGEFESVSKKLDELLTER--EKLNSVTSEQLKKLEQN--- 801 Query: 754 DAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAY 813 + +++ L IE +E+EL + K R E + M +L ++ +QL + +K Sbjct: 802 KSDLEKCKLNIEKLENELKEVKERKDNAENGVNKMNKELSNLSKEKEQLRIEQGKLEKKI 861 Query: 814 SE-YTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDM 872 E ++ ED + L ++ + +E +N EL N +E L L++ Sbjct: 862 QEQISVYEDSKIKFNQELESTEKQITDLQSNLESKNTELDNLN----KEKSGLMKELTEW 917 Query: 873 Q---QHYNALVEKANRTDLAESESTK-YQTQLRDLESNLKRITHEHQTLIVQKKKEIEDL 928 + + ++ALV K + + S K QT+ + S L I + + + I +L Sbjct: 918 KAKFKSHDALVPKLTEKLKSLANSYKELQTERDNYSSQLIEINKNKTSELSSLSESISNL 977 Query: 929 EIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQE----YKNNIENLNMNVEELNKM 984 +IE +D K+L+EK K I V++LE+Q+ E ++ E L ++ +EL ++ Sbjct: 978 KIE---------KD-KILDEK-SKLINKVSELESQITENCKIFEEEKEKLILSKDELEEL 1026 Query: 985 NLELIDKHVQKQQTQSPDYTEQYINEINK----LNALLKQKDEEIIALNQKI----NNAQ 1036 ++L ++ +++ +TQ + T + +E+NK LN LKQKD ++I L + + NN Sbjct: 1027 VIDL-NEQLKELETQK-ETTSKNADELNKSIANLNTQLKQKDSKLIELEELVEVTKNNLN 1084 Query: 1037 VSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELK 1096 S S VS+ +K+++ + ++++ E++++ ++ + K ++ Q +E D +L Sbjct: 1085 DS-ESQVSNLIAKISELDEENKSVKLEVEKLENEITEIKNSHKSAQ---KETDTLQTKLD 1140 Query: 1097 ETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLK-----VQEE-EEF 1150 ET+L + + K E + + + D N++ L+ +QE+ E Sbjct: 1141 ETELLLQSS--KEEILSLKNEYSSTLSDKENLENSEKKSSEKIEELEKNFSNLQEQFENI 1198 Query: 1151 IQERSVLQEQSAKLNTELQECYTKIIQL-ETLNTELTGHDVVN------QEQINQLKSKL 1203 E L+E+ + + ++ K+ Q ET+++ D +N ++ I+ L KL Sbjct: 1199 TAENKSLKEECSGTEEKFKDVNEKLDQYGETISSLSDEKDKLNGIIDDKEKIISNLNEKL 1258 Query: 1204 EQLNTEND------NLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHEL 1257 E ++ + D NLL +S + + E+ L+ + E + QKT + Sbjct: 1259 ESISEDIDIIEKAKNLLEEKLATMTSELNDSENGSSELRSLYDSLKIEFE-ELQKTNSDK 1317 Query: 1258 RVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVI 1317 L E+K+ L ++ + +++ ++ +++ L+ ++E L N D Sbjct: 1318 SANLKELENKHTSLTETQEILLEDKKKMESSINDYVKIKDDLEKEKEDLLNKYNVLEDKK 1377 Query: 1318 NQIEILRSE-------IEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQM---QEQSI 1367 +++EI+ E +E A + + N YK QE+ I Sbjct: 1378 DKLEIILEENNSSIKVLEHSIDALKKENEIYKNEIHDMKLQMESSNSEYKNKAGEQEKKI 1437 Query: 1368 LNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELK---DSEIYQKTHEYT 1424 + EE +LK S + E+K L L H E K D K + Sbjct: 1438 SRLKEECNKLKNSYEEKIEKL--------EVESKNLSLGHDTEKKQFEDKITSLKQEIIS 1489 Query: 1425 ITLTQRNDEFENVRQQLVEYEKRIEDLTYE-KESELAILRLKMHENANHYETMQKES-EI 1482 I +++ DE + ++ Q +K +E+L + SE ++ K+ N +++KE +I Sbjct: 1490 IEKSKKQDE-KVLKNQKNTLQKELEELKDQFTNSENEYIK-KLDNFQNEINSVRKEKLDI 1547 Query: 1483 ERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDE--- 1539 E V + +K S S K + L K+ +E + K +Q +LE Q E+ L +E Sbjct: 1548 EAVLNSKIETLKADLSKSEEKSLI-LEKSNKEHLIKMEVIQKSLEKQNKELDILGNEKDT 1606 Query: 1540 -ITNLQNMVRASSSKIQKHVSFASDTK 1565 NL N ++ +I V + K Sbjct: 1607 LTMNLNNEIKGLKEEINSKVDQIGNLK 1633 Score = 109 bits (263), Expect = 5e-22 Identities = 232/1087 (21%), Positives = 464/1087 (42%), Gaps = 117/1087 (10%) Query: 92 ESLANTLKQKEILMEKIKQYKE-LSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNT 150 E +LKQ+ I +EK K+ E + K T+ + + + + N Sbjct: 1477 EDKITSLKQEIISIEKSKKQDEKVLKNQKNTLQKELEELKDQFTNSENEYIKKLDNFQNE 1536 Query: 151 IKE-KDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXX 209 I + L + V +ET DL K EK I+E NK Sbjct: 1537 INSVRKEKLDIEAVLNSKIETLKADLS-KSEEKSLILEKSNKEHLIKMEVIQKSLEKQNK 1595 Query: 210 XXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISL 269 + + + N K+E + I + ++++ E + ++ ++ Sbjct: 1596 ELDILGNEKDTLTMNLNNEIKGLKEEINSKVDQIGNLKTELNTVSENMEDIQVRYDQLKE 1655 Query: 270 EHSKLAQELEQXXXXXXXXXXXXXXLAKQ--SIEPSCEEKTEI-----EEKGSLEIANMT 322 E S+++ +L + L S+E S K E +E ++I+ Sbjct: 1656 EKSEISDKLIESEEKLKENFSSISDLNSSVISLEASIISKDEEYTLLKKEFEEVKISKQE 1715 Query: 323 ELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKM 382 +K +LLE + +++TN E+KL + E + K L++ S N A + Sbjct: 1716 LDNQKDKLLEEYSI-MKRTN---ESKLKDLRNELDSKIIKFDKERKLLNEGSD-NIAQEY 1770 Query: 383 KSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEK-DTXXXXXXXX 441 + L E NQ K + ++I++LE I+S N L +K ++ ++ + Sbjct: 1771 SEKVTSLEEELRNQ---KIYSDDKISELEENIKSKNNALTEKSNLLQKRLEEIKELESTL 1827 Query: 442 XXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQL--KQELNDEIKDV--N 497 K L A ++ ++ E ++ + E NEI K++E L K++L EI+ N Sbjct: 1828 SKYKADLEATMKNSDLKNDEFENVCKELSVKE--NEIKKIEEILSSKEDLIAEIESQKDN 1885 Query: 498 VKD-LIEK---LKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDS 553 +KD L EK L E Q+ ++++ +N+ K + + K M ++DN K+ Sbjct: 1886 LKDELNEKSLLLDKKESQLEAFQEDVEVQKENLQKKITEYDNLQKLM--SLDN-KKLVKC 1942 Query: 554 NKEI----VRLTEELHHLSQ---KVAELEEEKGNLQLHLVDYDSG-RMIESDVYKKMIEM 605 K+I ++L +HL + K +LE E G + + + D + ++ D+ E+ Sbjct: 1943 EKQIEDLELKLESSSNHLKEQEGKYEKLEFESGENKKLISEKDELIQTLQLDISNNKDEI 2002 Query: 606 ENLAE------TRLKAISLLESQKFDLVQELHI-LQQKYDEVEDKLADISQLQSD----- 653 + L++ + L +K +V EL+ LQ+K +VE D+++L+ Sbjct: 2003 QKLSDKISTLQNNSENTELTLEEKEKMVDELNSKLQEKEAQVETLELDLNKLKETLDKEL 2062 Query: 654 QVCSEIKSVHLEEQIDALSASKK--ELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQ 711 + SE++ H + + + +K EL + I++ + D + + +K++E + D+ N L Sbjct: 2063 ESSSELQIAHDNLRDENIIQKQKITELKVKIDDSEKDSQVIIDNMKEMEENIMDLRNDLS 2122 Query: 712 N---YIQE-NMDLTDK------LEKMSAEKI-------SELLA--KINHEEQSKI-QTQF 751 + I++ N DL+ K L K AEK SEL+A K++ E++ + Q Sbjct: 2123 SKTIQIEKVNEDLSSKNSEIEQLNKKLAEKCAEYDSIKSELVASSKLSESEKNDMKQLSD 2182 Query: 752 GIDAKIQERDLYIENIE---SELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQE 808 I+ ++ +L EN++ S+L + + + + V + +E K L L Sbjct: 2183 EINELKEQLELKNENLKKVTSDLQIANNTSDKYNDELKVANNTIREIESKIPNLQKQLDL 2242 Query: 809 KQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQK-KNQILLE----ENQ 863 K+ Y++ + +L +L ++ K++ ++ E +L+K KN +++E +N Sbjct: 2243 KEIEYNDTLSSKKDLDKKLDNFSKESEILSKEVKSLKKEKLDLEKEKNDLIVELDKYKND 2302 Query: 864 NLQISLSDMQQHYNA------LVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTL 917 + ++ + + N ++ ++ + + ++ + LES++K + E Sbjct: 2303 IIDLNNTLKENEKNGSEVETEIIGLKDKIEFYKLNVSQLNEEKGKLESDIKTLVGERDDK 2362 Query: 918 IVQKKKEIEDL--EIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLN 975 + + EI +L ++E I A + KV ++ + + +++E L+E N+++ N Sbjct: 2363 LKSSQSEIIELTNKLESFKDISVAYEESKVESDGLKNKL---SEIEKSLEESNENVDSAN 2419 Query: 976 MNVEELNKMNLELIDKHVQ---KQQTQSPDYTE--QYINEINKLNALLKQKDEEII-ALN 1029 + +L MN +L +++ K Q D TE + I +INKL K EE I +L Sbjct: 2420 KEISDLKVMNDKLQSHNLELEDKFQQLKNDTTETNRKIQDINKLKEEESSKAEEKIRSLT 2479 Query: 1030 QKINNAQVSY----------------MSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLD 1073 ++I + + M +VSD + K +++ KLE + E+ S + + Sbjct: 2480 EEIEKLKNDFKKNESKAPDTSEIDDLMLLVSDLDEKNSKYKAKLEELGVELS--SDEETE 2537 Query: 1074 SKQHNEE 1080 S +EE Sbjct: 2538 SDDTDEE 2544 Score = 41.1 bits (92), Expect = 0.25 Identities = 36/139 (25%), Positives = 68/139 (48%), Gaps = 11/139 (7%) Query: 1431 NDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHEN---ANHYETMQKESEIERVKL 1487 ND F + + E E ++E+L+ + ++ ++ +E N+YE +KE E E V Sbjct: 718 NDMFVSKGDVINELELKVEELSNKSKNSISDYESIKNEYDILKNNYE--EKEGEFESVS- 774 Query: 1488 IEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMV 1547 ++L+ +TE LN +E K LE+ + + + +E E E+ + + N +N V Sbjct: 775 -KKLDELLTEREKLNSVTSEQLKKLEQNKSDLEKCKLNIEKLENELKEVKERKDNAENGV 833 Query: 1548 RASSSKIQKHVSFASDTKQ 1566 +K+ K +S S K+ Sbjct: 834 ----NKMNKELSNLSKEKE 848 >UniRef50_A2FSZ8 Cluster: Viral A-type inclusion protein, putative; n=1; Trichomonas vaginalis G3|Rep: Viral A-type inclusion protein, putative - Trichomonas vaginalis G3 Length = 4045 Score = 196 bits (479), Expect = 3e-48 Identities = 289/1490 (19%), Positives = 632/1490 (42%), Gaps = 124/1490 (8%) Query: 147 LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXX 206 L N I+ NAL+ Q + K ++ + +KI + +QI++ +NK Sbjct: 844 LQNDIESITNALNQSQNENKELK----EENQKIEKSNQILQYENKEVKEQKEKLQNQIDD 899 Query: 207 XXXXXEDTKQQMTKMQENFIAMEAEWKDEK---QRLLKDIESK--DVRISSLEEANKLLE 261 + + ++ ++ E ++ E +++ Q +LKD+E+K ++ LE ++ E Sbjct: 900 LKNQNSNLQNKVDELNEEISSINEEKSNQEKEYQEMLKDLETKLKNLEAERLESNKEITE 959 Query: 262 AARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANM 321 + + + S ++ L + L +Q+ + E + + L + N Sbjct: 960 ILELDTTFDDSTISDHLRKQCEQLKS-------LIEQNKNQNEEIQNLKSQNEDLTVKN- 1011 Query: 322 TELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASK 381 E+ K++ + C + +T+++ + ++ + + + + S S+K T ++ Sbjct: 1012 EEMKKELMNNQTTICDLIKTSEDKDKEIDDLKQKIEKLKSEIDN-----SKKQLDTTLTE 1066 Query: 382 MK-SPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXX 440 K S + +L S+ + DKK KLE +Q+L K+ + + + K+ Sbjct: 1067 FKVSNFDELQSQISRNNDDKK-------KLEQKVQNLQKENEEMKIKLENKENERKSLSS 1119 Query: 441 XXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKD 500 L +LQ + H I +G ++++ + + + +L +E+ D+I + N+ Sbjct: 1120 LESENILLKQKLQNNDKLHQ-----IQIGELQKEIDVLNQTKSKLSKEV-DDITNENIT- 1172 Query: 501 LIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQM---QKTIDNFSKVSDSNKEI 557 L ++ + N+E+ +IK ++++L+L Q + ID +K+SD E+ Sbjct: 1173 LKNQINTTFSMSIDENNELKKKLNQLIKENNSYQLQLNQSVPKEDFIDLQNKISDLENEL 1232 Query: 558 ---VRL---TEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAET 611 V L E +L + ++ ++ K ++++ + + + ++ KM ++N + Sbjct: 1233 QNSVSLKDYNESQAYLEKTMSTVDNLKSSVKVAQKELQNMKQTMNNQNTKMTSLQNTLQD 1292 Query: 612 RLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDAL 671 + IS L+ + L ++ L+ + + +K+ + LQ + S I++ ++ Q++ Sbjct: 1293 KDSEISDLKEKNSQLELKIEDLEGEKSKDNEKMKN-KDLQIKLMESTIEN--MKSQLNES 1349 Query: 672 SASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEK 731 + E AL+ L+ KE + +++ EN MN QN EN + + + + Sbjct: 1350 QSLNNEYALLQSTLQ-SKENQFSKLQN-ENVMLQTMN--QNLTNENASMKENHNREIQKL 1405 Query: 732 ISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENI-----ESELSKYKSRICRLEESIA 786 ++L K E+ + Q + + ++DL I N+ E+EL +I L Sbjct: 1406 QNDLQNKEFQEKMINSELQ-KLKESLTQKDLQISNLSRYSNENELKNKNIQIEYLTNENK 1464 Query: 787 VMEDRRYSLE---RKADQ----LGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEK 839 +++ LE RK D + S L+ K+ E L N + + + +E Sbjct: 1465 KLKETNLDLESQIRKKDNEINDINSNLKRKENQLQETENTNRNLQNDIKRKQNENNDLEN 1524 Query: 840 QLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLA----ESESTK 895 ++ +++ + Q N ++ + + + D++ L +K++ L+ ES++ + Sbjct: 1525 EINKLKDLLSKSQHDNDLVNNDLKRKDLQNRDLENKLKNLKDKSSELQLSLSRMESDNKR 1584 Query: 896 YQTQLRDLESNLKRITHEHQTL---IVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEK 952 Q+ +LE++LK+ + +L + +K+ +I +L+ + NT + + L + + Sbjct: 1585 KDNQIIELENDLKKSKEINNSLSNDLKRKENQISELQNQQNTDLIKKQNENNDLMNENKS 1644 Query: 953 NIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEIN 1012 E + + E++ + ++ + + +L K +L K V + S N+I Sbjct: 1645 LKELIAKKESENDSINSELKRRTLQINDLEKEIKDLASKRVDENNDLS--------NQIK 1696 Query: 1013 KLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLL 1072 + L+ +K+ E N INN S +D + LA+ +++ + E++R+S + Sbjct: 1697 NMKDLISKKETE----NNSINNELRRVNSQNNDLKELLAKKESEINAINNELKRISSENN 1752 Query: 1073 DSKQHNEELQILVREQ----DDQIKELKET--KL----TFEMNIPKTEGMIISSTIEPMS 1122 D K N + + ++Q +Q+ +LK KL T E N K + +I I+ S Sbjct: 1753 DLKDINSKSENNYQDQLKNLKNQLTQLKNENQKLMKSSTEEKN--KLKDLINEKNIQIQS 1810 Query: 1123 DDANNVDXXXXXXXXXXXXLKVQEE-EEFIQERSVLQEQSAKLNTELQECYTKIIQLETL 1181 + N D +Q++ +E + SVL ++ KL EL T+I L+ Sbjct: 1811 LQSKNEDLVNNQSKINNKLESIQKDLDEKENQNSVLISENEKLQNELMSSKTEIQTLDQK 1870 Query: 1182 NTELTG-------HDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSS--ISSAVDQRG 1232 TE ++ QIN LK KL L N+ + +L+ I SA +Q+ Sbjct: 1871 ETEFNDKLREMERNNRSLSSQINDLKEKLNNLTETNEKISDENTKLKQQMKIESANNQKQ 1930 Query: 1233 FEIAELWKQHLAQREADFQKTEHELR-VQLSAFESKYEQLLDSVQSS--TQEETNKIVTM 1289 + E K + Q E + K++ + L + + EQ ++ ++ S +EE+ I+ Sbjct: 1931 LKQLETEKLNRLQEENNKLKSQISKKDSDLQKLKQESEQTINDLKESLLNKEESLSILEK 1990 Query: 1290 ------EQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXX 1343 +Q+ + + + + +QEK N L+++I+ + Sbjct: 1991 SADFITKQIDGKSKSINENSQIIEQMQEKIIQKDNATTDLQNKIKQLESQLQQNEKDNDK 2050 Query: 1344 XXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVL 1403 +L+ K ++E+ + NE N+ K + +N+ EAK Sbjct: 2051 VKQLQT-ELKEHQLKIKNLEEKIVKLNNENNSLQKLINSKDDEKVKQLQNNINENEAKTK 2109 Query: 1404 ELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILR 1463 Q++ SE + + + + + ++ ++++ DL K SE I Sbjct: 2110 TFEDQIQKLTSE----NNSLRKNINENDSKVKSYQEEIQNLTNEKNDLI--KSSETKIKE 2163 Query: 1464 LKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQ 1523 L E Q+ ++ R K +L K E NK +++L++ L E K NE++ Sbjct: 2164 LTESSKNQISELNQRLQDVTR-KSDLDLQKKEMEIQIANKNISDLHQQLLESNQKLNEIK 2222 Query: 1524 TALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLD 1573 NQ++++ +++T +++ ++I+ ++ +S Q + D Sbjct: 2223 LQANNQQLQLKQKENDLTTANSIIETLKNEIENTMNKSSILVQNEMNKKD 2272 Score = 184 bits (447), Expect = 2e-44 Identities = 311/1531 (20%), Positives = 669/1531 (43%), Gaps = 140/1531 (9%) Query: 144 VTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKN---KATTXXXXXX 200 + ++ + I +K+ + + +++ + + DL+E + +K+ I A N K + Sbjct: 1695 IKNMKDLISKKETENNSINNELRRVNSQNNDLKELLAKKESEINAINNELKRISSENNDL 1754 Query: 201 XXXXXXXXXXXEDT----KQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEA 256 +D K Q+T+++ + +EK +L I K+++I SL+ Sbjct: 1755 KDINSKSENNYQDQLKNLKNQLTQLKNENQKLMKSSTEEKNKLKDLINEKNIQIQSLQSK 1814 Query: 257 NKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXL------AKQSIEPSCEEKTEI 310 N+ L + +I+ + + ++L++ L +K I+ +++TE Sbjct: 1815 NEDLVNNQSKINNKLESIQKDLDEKENQNSVLISENEKLQNELMSSKTEIQTLDQKETEF 1874 Query: 311 EEKGSLEIANMTELTKKI-ELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPL 369 +K N L+ +I +L E LN + +TN+++ ++ + + K S+ ++K Sbjct: 1875 NDKLREMERNNRSLSSQINDLKEKLN-NLTETNEKISDENTKLKQQMKIESANNQKQLKQ 1933 Query: 370 ISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVIS 429 + + ++++ ++L S+ +D+D + K E E I L + L++KE +S Sbjct: 1934 LETEK----LNRLQEENNKLKSQISKKDSDLQKLKQES---EQTINDLKESLLNKEESLS 1986 Query: 430 EKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDV-NEIAKVQEQLKQE 488 + GK I + +Q E +I T D+ N+I +++ QL+Q Sbjct: 1987 ILEKSADFITKQIDGKSKSINENSQIIEQMQE--KIIQKDNATTDLQNKIKQLESQLQQN 2044 Query: 489 L--NDEIKDVN--VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTI 544 ND++K + +K+ K+K+ EE+I +LN+E ++ K +I K + K+K Q+Q I Sbjct: 2045 EKDNDKVKQLQTELKEHQLKIKNLEEKIVKLNNENNSLQK-LINSKDDEKVK--QLQNNI 2101 Query: 545 -DNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKM- 602 +N +K +I +LT E + L + + E + + + Q + + + + +D+ K Sbjct: 2102 NENEAKTKTFEDQIQKLTSENNSLRKNINENDSKVKSYQEEIQNLTNEK---NDLIKSSE 2158 Query: 603 IEMENLAETRLKAISLLESQKFDLVQELHI-LQQKYDEVE---DKLADISQ--LQSDQVC 656 +++ L E+ IS L + D+ ++ + LQ+K E++ ++D+ Q L+S+Q Sbjct: 2159 TKIKELTESSKNQISELNQRLQDVTRKSDLDLQKKEMEIQIANKNISDLHQQLLESNQKL 2218 Query: 657 SEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQE 716 +EIK L+ L +KE L N I+ L+N+ E+ MNK +Q Sbjct: 2219 NEIK---LQANNQQLQLKQKENDLTTAN---------SIIETLKNEIENTMNKSSILVQN 2266 Query: 717 NMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKS 776 M+ D++ + E++S L + N EE SK+Q ++ I++ E++ K Sbjct: 2267 EMNKKDEIIQNLQEQLSNLKQETN-EEISKLQNDKNNQTELLN---LIKSKNDEINNLKE 2322 Query: 777 RICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRV 836 I R ++ +M+ +RY + + L + Q S L+ L + + ++ Sbjct: 2323 -INRQKDQ-QIMDLKRYE---QTELLNLSNNDDQNRSSSIVYNSSTLMKSLRQVKEDSQI 2377 Query: 837 VEK----QL----LEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDL 888 EK QL ++ + E K LQ KN E+ ++L+ ++++ + N + E++ ++ Sbjct: 2378 REKFIDDQLKSLSMQKDEEIKNLQNKNSEKDEKIRDLEKQINNLSDNSNHIKEESMINEV 2437 Query: 889 A-ESESTKYQTQLRDLESNLKRITHEHQTL---IVQKKKEIEDLEIEFNTQIESAIRD-K 943 +S ++ ++++ ++ E+Q L I + K+I+D E E N ++ I+ Sbjct: 2438 KLKSNIDSMNDKILQMQNDSNQLFKENQNLRNSIDKLNKQIKDFEQE-NESLKQTIQSFT 2496 Query: 944 KVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDY 1003 K+ NE E+N + + + N NL + ++ NK +++++ + ++ D Sbjct: 2497 KLNNELTEENEKIYKKYNDLINNNAVNENNLQVMKDQNNKNQIKILELTRNLEMSKFND- 2555 Query: 1004 TEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEE 1063 +Q ++IN+L L +K E++I L Q Q++ S D + L Q ++ + E Sbjct: 2556 -DQNKDKINELETDLAEK-EKLIKLLQN----QLTVSSSDKDMKQILQQKDEEIRKLNEN 2609 Query: 1064 MQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSD 1123 ++ ++ EE E +Q+KE + +++ E K E I + I Sbjct: 2610 NGKIKVLQNQIEKMKEENNSKTNELLNQLKESENKRISLEAEKKKLEIEISNLNI----- 2664 Query: 1124 DANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNT 1183 D NN+ + + +E ++R+++ + K +L TK L+ NT Sbjct: 2665 DDNNLKLMEQKMKEMSNVINKLQSQESDKDRTIMNQ--TKQIKKLGSIMTKAKSLKAENT 2722 Query: 1184 ELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELR-SSISSAVDQRGFEIAELWKQ- 1241 L ++ + ++ + LN+ + + S + + S + V + E +L + Sbjct: 2723 LLRSQ--ISDLESSKTEISSASLNSSSPQMSSLSQKKKISRLEKQVTELLQENEDLKMEI 2780 Query: 1242 -HLAQREADFQKTEHE-LRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQ----VTSL 1295 H + + + E+E L++++ + E++ ++ + +++ + K+ ME+ ++S Sbjct: 2781 IHKSTSDENLDSLENEKLQLRIKSLETQLNKMKE-IENENKNLKTKVSFMEENSKKLSSE 2839 Query: 1296 QNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTE 1355 L K ++ + EIL ++ + + L T Sbjct: 2840 IESLIKKNGEMKINLVSLKSIKENFEILEKSSKEREAEYSKYRASQEKKVNDLQTKLSTL 2899 Query: 1356 NQSYKQMQEQSILNINE-----ENAQLKKS----SXXXXXXXXXXXXRVNDAEAKVLELT 1406 Y ++ ++ +N+ E N +LK++ S +N ++ +L+ Sbjct: 2900 ENDYSDLKNENEMNVLEIQKITNNLKLKENQLQRSLDNDKTMDSLQATLNTKTSENQKLS 2959 Query: 1407 HQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKM 1466 +L L+++EI E + + + + +K +DL ++ +++ L ++ Sbjct: 2960 TELVLRNNEIKDLKDEIGKVNNDKEELMKIINVNNTLVQKLQKDLL-DRNNQIEFLNKEI 3018 Query: 1467 HENANHYETMQKESEIERVKLIEELNVKITESV-SLNKQVAELNKALE---EEV------ 1516 EN ++ ES ++ + + ++ E++ SL+ L +E +E+ Sbjct: 3019 QENKEEFDQKINESNT-KIDELNNIIKQMKETIKSLSNDKDNLKSTIEGNEDEIHRIANK 3077 Query: 1517 --AKTNEMQTAL-ENQEI--EIVTLNDEITNLQ-----------NMVRASSSKIQKHVSF 1560 K+N++ L EN+++ EI N EI NL+ N + S S IQ H+ Sbjct: 3078 LQKKSNKINFILAENEKLQNEIEKNNKEIENLRKKLKSNEEKLNNQQKESKSSIQNHLQI 3137 Query: 1561 ASDTKQGRDEQLDNTMNKELLDAVPRAELDL 1591 +D K+ +E + KE E DL Sbjct: 3138 NNDLKKENEELSNQLKLKEDEKQKQNEEFDL 3168 Score = 181 bits (440), Expect = 2e-43 Identities = 326/1504 (21%), Positives = 648/1504 (43%), Gaps = 164/1504 (10%) Query: 144 VTHLSNTIKEKDNALSVLQVKMKIMETTILDLQ-EKINEKDQIIEAKNKATTXXXXXXXX 202 +T L NT+++KD+ +S L+ K +E I DL+ EK + +++ KNK Sbjct: 1283 MTSLQNTLQDKDSEISDLKEKNSQLELKIEDLEGEKSKDNEKM---KNK---------DL 1330 Query: 203 XXXXXXXXXEDTKQQMTKMQ--ENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLL 260 E+ K Q+ + Q N A+ K+ +++++V + ++ N+ L Sbjct: 1331 QIKLMESTIENMKSQLNESQSLNNEYALLQSTLQSKENQFSKLQNENVMLQTM---NQNL 1387 Query: 261 EAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIAN 320 + H++ Q+L Q Q ++ S +K +++ +N Sbjct: 1388 TNENASMKENHNREIQKL-QNDLQNKEFQEKMINSELQKLKESLTQK-DLQISNLSRYSN 1445 Query: 321 MTELTKK---IELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRN 377 EL K IE L + N ++++TN +LE+++ E ++S K+ + + N Sbjct: 1446 ENELKNKNIQIEYLTNENKKLKETNLDLESQIRKKDNEINDINSNLKRKENQL--QETEN 1503 Query: 378 TASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXX 437 T +++ + +E N D + +INK + L Q N DLV+ + + KD Sbjct: 1504 TNRNLQNDIKRKQNE--NNDLENEINK--LKDLLSKSQHDN-DLVNND--LKRKDLQNRD 1556 Query: 438 XXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVN 497 ++LQL ME N N+I +++ LK+ K++N Sbjct: 1557 LENKLKNLKDKSSELQLS-LSRME-------SDNKRKDNQIIELENDLKKS-----KEIN 1603 Query: 498 VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEI 557 L LK E QI++L ++ N ++IK K N L K++ +S + Sbjct: 1604 -NSLSNDLKRKENQISELQNQ---QNTDLIK-KQNENNDLMNENKSLKELIAKKESEND- 1657 Query: 558 VRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAIS 617 + EL + ++ +LE+E +L VD + +D+ ++ M++L IS Sbjct: 1658 -SINSELKRRTLQINDLEKEIKDLASKRVDEN------NDLSNQIKNMKDL-------IS 1703 Query: 618 LLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLE--EQIDALSASK 675 E++ + EL + + +++++ LA + + + + +E+K + E + D S S+ Sbjct: 1704 KKETENNSINNELRRVNSQNNDLKELLAK-KESEINAINNELKRISSENNDLKDINSKSE 1762 Query: 676 KELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISEL 735 ++NLK QL + L + NKL++ I E L+ + + ++ Sbjct: 1763 NNYQDQLKNLKNQLTQLKNENQKLMKSSTEEKNKLKDLINEKNIQIQSLQSKNEDLVNN- 1821 Query: 736 LAKINHEEQSKIQTQFGIDAKIQERDLYI---ENIESELSKYKSRICRLEESIAVMEDRR 792 +KIN++ +S Q +D K + + I E +++EL K+ I L++ D+ Sbjct: 1822 QSKINNKLES---IQKDLDEKENQNSVLISENEKLQNELMSSKTEIQTLDQKETEFNDKL 1878 Query: 793 YSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQ 852 +ER L S + + ++ + T + +E ++ + +E + + + E + Sbjct: 1879 REMERNNRSLSSQINDLKEKLNNLT-ETNEKISDENTKLKQQMKIESANNQKQLKQLETE 1937 Query: 853 KKNQILLEENQNLQISLSDMQQHYNALVEKANRT--DLAESESTKYQTQLRDLESNLKRI 910 K N+ L EEN L+ +S L +++ +T DL ES K + L LE + I Sbjct: 1938 KLNR-LQEENNKLKSQISKKDSDLQKLKQESEQTINDLKESLLNK-EESLSILEKSADFI 1995 Query: 911 T----------HEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQL 960 T +E+ +I Q +++I + T +++ I+ + ++ EK+ + V QL Sbjct: 1996 TKQIDGKSKSINENSQIIEQMQEKIIQKD-NATTDLQNKIKQLESQLQQNEKDNDKVKQL 2054 Query: 961 EAQLQEYKNNIENLNMNVEELNKMN---LELID-------KHVQKQQTQSPDYTEQYINE 1010 + +L+E++ I+NL + +LN N +LI+ K +Q ++ T+ + ++ Sbjct: 2055 QTELKEHQLKIKNLEEKIVKLNNENNSLQKLINSKDDEKVKQLQNNINENEAKTKTFEDQ 2114 Query: 1011 INKL----NALLK---QKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEE 1063 I KL N+L K + D ++ + ++I N ++ E+K+ + T +N E Sbjct: 2115 IQKLTSENNSLRKNINENDSKVKSYQEEIQNLTNEKNDLIKSSETKIKELTESSKNQISE 2174 Query: 1064 M-QRVS----KQLLDSKQHNEELQIL----------VREQDDQIKELKETKLTFEMNIPK 1108 + QR+ K LD ++ E+QI + E + ++ E+K ++ + + Sbjct: 2175 LNQRLQDVTRKSDLDLQKKEMEIQIANKNISDLHQQLLESNQKLNEIKLQANNQQLQLKQ 2234 Query: 1109 TEGMI--ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNT 1166 E + +S IE + ++ N ++ +++E IQ LQEQ + L Sbjct: 2235 KENDLTTANSIIETLKNEIEN----TMNKSSILVQNEMNKKDEIIQN---LQEQLSNLKQ 2287 Query: 1167 ELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISS 1226 E E +K+ + TEL ++IN LK Q + + +L ++S+ Sbjct: 2288 ETNEEISKLQNDKNNQTELLNLIKSKNDEINNLKEINRQKDQQIMDLKRYEQTELLNLSN 2347 Query: 1227 AVDQ-RGFEI---AELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEE 1282 DQ R I + + L Q + D Q E + QL + + ++ + ++Q+ E+ Sbjct: 2348 NDDQNRSSSIVYNSSTLMKSLRQVKEDSQIREKFIDDQLKSLSMQKDEEIKNLQNKNSEK 2407 Query: 1283 TNKIVTME-QVTSL-QNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAF--XXXX 1338 KI +E Q+ +L N KEE + N + +++ + + + D F Sbjct: 2408 DEKIRDLEKQINNLSDNSNHIKEESMINEVKLKSNIDSMNDKILQMQNDSNQLFKENQNL 2467 Query: 1339 XXXXXXXXXXXXDLRTENQSYKQ-MQEQSILN--INEENAQLKK-------SSXXXXXXX 1388 D EN+S KQ +Q + LN + EEN ++ K ++ Sbjct: 2468 RNSIDKLNKQIKDFEQENESLKQTIQSFTKLNNELTEENEKIYKKYNDLINNNAVNENNL 2527 Query: 1389 XXXXXRVNDAEAKVLELTHQLEL---KDSEIYQKTHEYTITLTQRNDEFENVRQQLV--E 1443 + N + K+LELT LE+ D + K +E L ++ + ++ QL Sbjct: 2528 QVMKDQNNKNQIKILELTRNLEMSKFNDDQNKDKINELETDLAEKEKLIKLLQNQLTVSS 2587 Query: 1444 YEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNK 1503 +K ++ + +K+ E+ K++EN + +Q ++IE++K EE N K E ++ K Sbjct: 2588 SDKDMKQILQQKDEEIR----KLNENNGKIKVLQ--NQIEKMK--EENNSKTNELLNQLK 2639 Query: 1504 QVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMV-RASSSKIQKHVSFAS 1562 + +LE E K + L + + + ++ + N++ + S + K + + Sbjct: 2640 ESENKRISLEAEKKKLEIEISNLNIDDNNLKLMEQKMKEMSNVINKLQSQESDKDRTIMN 2699 Query: 1563 DTKQ 1566 TKQ Sbjct: 2700 QTKQ 2703 Score = 173 bits (421), Expect = 3e-41 Identities = 265/1303 (20%), Positives = 579/1303 (44%), Gaps = 114/1303 (8%) Query: 337 QIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSET--- 393 ++ Q N L + + E +++ + K+ + + +MK + L E Sbjct: 203 ELTQENDNLRENIENLNKEIESLQNKIKENQ---NTPQTQQQYEEMKKKYENLKIENNSQ 259 Query: 394 ---LNQDTDKKIN-KNEIAKL--EMVIQSLNKDLVDKE-YVISEKDTXXXXXXXXXXGKD 446 ++Q TD+ + EI KL E++ L D K+ Y S++ KD Sbjct: 260 KILIDQRTDELTKARQEIGKLQQELMGDDLPNDKAFKDIYKESQEKIVNLQTENNQLKKD 319 Query: 447 TLIAQLQLEH--------QQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNV 498 A+ + E+ ++ SL++ N + +N++ ++++ + + D+ Sbjct: 320 LENAKTEQENLNQKLNNLNNNLNDNSLLNKSLN-DQINQLKVELQKMQNTIYKKDGDLQE 378 Query: 499 KD-LIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFS----KVSDS 553 KD IE+LK ++E++ NK + ++ + + + +F+ +++D+ Sbjct: 379 KDDEIEQLKQTLNAQKTFSNELEETNKKLKEMLNQNSKSDLTNSSFLSSFNLTKQRLNDT 438 Query: 554 NKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRL 613 +E +L +L L Q++ L++E NL+ Y S++ I + + Sbjct: 439 KQENEQLQNQLMQLQQQLLILKQENENLKEKQNSYSDSLNNSSNMSALDISGSDFVQIDQ 498 Query: 614 KAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSA 673 I E + L + L++K + E+ S+ +D S ++ + L++ +D A Sbjct: 499 AIIDQYEQRIKSLTDNISELREKISQKEN-----SEKSNDSQRS-LELIQLKKSLD--KA 550 Query: 674 SKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKIS 733 K+ ++ EN KL+ QL K ++ ++N L +E L L+K K Sbjct: 551 KKENYSIKEENFKLN--QLLNNYKRKIDNLNQLLNDLNP--KEIKLLLSSLKKDFLLKRD 606 Query: 734 ELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRY 793 + + I ++K + + +A + DL IEN+++EL K + L+ S A E+++ Sbjct: 607 DFIKYIR---KAKNEVR---NALSENSDL-IENLQNELLNMKEK---LQNSKA--ENKQI 654 Query: 794 -SLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQ 852 SL+ K + L + + QK E N + L D + + +++ ENKEL+ Sbjct: 655 LSLQPKINDLNKIMTQIQKENERLQKTNKEKNNEIEKLKDENENLVSNNKKLQTENKELK 714 Query: 853 K-------KNQILLEENQNLQISLSDMQQHYNALVE-KANRTDLAESESTKYQTQLRDLE 904 + +N LL EN +L L++++ L + K + L + + L D Sbjct: 715 ENLEKETSQNSDLLNENSDLNDKLNELRNQIKTLNDDKTKQNQLLQKNLSNQLKDLLDEN 774 Query: 905 SNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRD-KKVLNEKYEKN---IEYVTQL 960 ++LK + Q+ Q +K+I+DL Q ES ++ + +NEK +N E + L Sbjct: 775 NSLKDQLAQLQSSNNQLQKDIKDL----TRQNESKTKELQSKINEKENENQNLTEKLNSL 830 Query: 961 EAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQ 1020 ++Q+Q +N E+L ++E + + + Q ++ + E+ +I K N +L+ Sbjct: 831 QSQIQILQNGNEDLQNDIESITNA--------LNQSQNENKELKEEN-QKIEKSNQILQY 881 Query: 1021 KDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEE 1080 +++E+ +K+ N + D +++ + K++ + EE+ ++++ +E Sbjct: 882 ENKEVKEQKEKLQN-------QIDDLKNQNSNLQNKVDELNEEISSINEE---KSNQEKE 931 Query: 1081 LQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXX 1140 Q ++++ + ++K L+ +L E N TE + + +T DD+ D Sbjct: 932 YQEMLKDLETKLKNLEAERL--ESNKEITEILELDTTF----DDSTISDHLRKQCEQLKS 985 Query: 1141 XLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLK 1200 ++ + + +E L+ Q+ L + +E +++ +T +L ++I+ LK Sbjct: 986 LIEQNKNQN--EEIQNLKSQNEDLTVKNEEMKKELMNNQTTICDLIKTSEDKDKEIDDLK 1043 Query: 1201 SKLEQLNTENDN----LLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHE 1256 K+E+L +E DN L +T+ E + S + Q K+ L Q+ + QK E Sbjct: 1044 QKIEKLKSEIDNSKKQLDTTLTEFKVSNFDEL-QSQISRNNDDKKKLEQKVQNLQKENEE 1102 Query: 1257 LRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQ-NKLQDKEEHLRNLQEKYAD 1315 ++++L E++ + L S++S K+ +++ +Q +LQ + + L + K + Sbjct: 1103 MKIKLENKENERKSL-SSLESENILLKQKLQNNDKLHQIQIGELQKEIDVLNQTKSKLSK 1161 Query: 1316 VINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENA 1375 ++ I ++++ L EN SY+ QS+ + + Sbjct: 1162 EVDDITNENITLKNQINTTFSMSIDENNELKKKLNQLIKENNSYQLQLNQSVPKEDFIDL 1221 Query: 1376 QLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLE-LKDS-EIYQKT-HEYTITLTQRND 1432 Q K S N+++A + + ++ LK S ++ QK T+ +N Sbjct: 1222 QNKISDLENELQNSVSLKDYNESQAYLEKTMSTVDNLKSSVKVAQKELQNMKQTMNNQNT 1281 Query: 1433 EFENVRQQLVEYEKRIEDLTYEKES--ELAILRLKMHENANHYETMQKESEIERVK-LIE 1489 + +++ L + + I DL EK S EL I L+ ++ ++ + K+ +I+ ++ IE Sbjct: 1282 KMTSLQNTLQDKDSEISDLK-EKNSQLELKIEDLEGEKSKDNEKMKNKDLQIKLMESTIE 1340 Query: 1490 ELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRA 1549 + ++ ES SLN + A L L+ +K N+ + L+N+ + + T+N +TN ++ Sbjct: 1341 NMKSQLNESQSLNNEYALLQSTLQ---SKENQF-SKLQNENVMLQTMNQNLTNENASMKE 1396 Query: 1550 SSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDLA 1592 + ++ + + K+ +++ +++ + K L +++ + +L ++ Sbjct: 1397 NHNREIQKLQNDLQNKEFQEKMINSELQK-LKESLTQKDLQIS 1438 Score = 173 bits (420), Expect = 4e-41 Identities = 321/1619 (19%), Positives = 694/1619 (42%), Gaps = 152/1619 (9%) Query: 57 AQKCLENAAL-VSKRIKE--HRKATAELLGRPFVPGIS---ESLANTLKQKEILMEKIKQ 110 AQK N +K++KE ++ + ++L F+ + + L +T ++ E L ++ Q Sbjct: 392 AQKTFSNELEETNKKLKEMLNQNSKSDLTNSSFLSSFNLTKQRLNDTKQENEQLQNQLMQ 451 Query: 111 YKE---LSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNALSVLQVKMKI 167 ++ + K+ + + D++ S+ ++ + + ++K Sbjct: 452 LQQQLLILKQENENLKEKQNSYSDSLNNSSNMSALDISG-SDFVQIDQAIIDQYEQRIKS 510 Query: 168 METTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIA 227 + I +L+EKI++K+ ++ + + K++ K+ + Sbjct: 511 LTDNISELREKISQKENSEKSNDSQRSLELIQLKKSLDKAKKENYSIKEENFKLNQLLNN 570 Query: 228 MEAEWKDEKQRLLKDIESKDVRI--SSLEEANKLLEAARFEISLEHSKLAQELEQXXXXX 285 + + D +LL D+ K++++ SSL++ + LL+ F + +K E+ Sbjct: 571 YKRKI-DNLNQLLNDLNPKEIKLLLSSLKK-DFLLKRDDFIKYIRKAK--NEVRNALSEN 626 Query: 286 XXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKEL 345 E K E ++ SL+ + +L K + ++ N ++++TNKE Sbjct: 627 SDLIENLQNELLNMKEKLQNSKAENKQILSLQ-PKINDLNKIMTQIQKENERLQKTNKEK 685 Query: 346 ENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKN 405 N++ + E++ + S +KK + + ++ SQ +S+ LN+++D N Sbjct: 686 NNEIEKLKDENENLVSNNKK-----LQTENKELKENLEKETSQ-NSDLLNENSDLNDKLN 739 Query: 406 EIAKLEMVIQSLNKDLVDKEYVISE--KDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGP 463 E L I++LN D + ++ + + KD L AQLQ + Q Sbjct: 740 E---LRNQIKTLNDDKTKQNQLLQKNLSNQLKDLLDENNSLKDQL-AQLQSSNNQLQ--- 792 Query: 464 SLIHVGTNTEDVNEIAKVQEQLKQELNDEI--KDVNVKDLIEKLKSAEEQITQL-NDEID 520 +D+ ++ + E +EL +I K+ ++L EKL S + QI L N D Sbjct: 793 ---------KDIKDLTRQNESKTKELQSKINEKENENQNLTEKLNSLQSQIQILQNGNED 843 Query: 521 AAN-----KNMIKVKSNHKLKLKQMQKTIDNFSKVSD-SNKEIVRLTEELHHLSQKVAEL 574 N N + N +LK+ + I+ +++ NKE+ E+ L ++ +L Sbjct: 844 LQNDIESITNALNQSQNENKELKEENQKIEKSNQILQYENKEV---KEQKEKLQNQIDDL 900 Query: 575 EEEKGNLQLHL----VDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQEL 630 + + NLQ + + S +S+ K+ EM ET+LK + + + E+ Sbjct: 901 KNQNSNLQNKVDELNEEISSINEEKSNQEKEYQEMLKDLETKLKNLEAERLESNKEITEI 960 Query: 631 HILQQKYDEVEDKLADISQLQSDQVCSEI-KSVHLEEQIDALSASKKELALVIENLKLDK 689 L +D + ++D + Q +Q+ S I ++ + E+I L + ++L + E +K + Sbjct: 961 LELDTTFD--DSTISDHLRKQCEQLKSLIEQNKNQNEEIQNLKSQNEDLTVKNEEMKKEL 1018 Query: 690 EQLYGTIKDL-----ENDKE--DIMNKLQNYIQE----NMDLTDKLEKMSAEKISELLAK 738 TI DL + DKE D+ K++ E L L + EL ++ Sbjct: 1019 MNNQTTICDLIKTSEDKDKEIDDLKQKIEKLKSEIDNSKKQLDTTLTEFKVSNFDELQSQ 1078 Query: 739 I--NHEEQSKIQTQF-GIDAKIQERDLYIENIESE---LSKYKSRICRLEESI----AVM 788 I N++++ K++ + + + +E + +EN E+E LS +S L++ + + Sbjct: 1079 ISRNNDDKKKLEQKVQNLQKENEEMKIKLENKENERKSLSSLESENILLKQKLQNNDKLH 1138 Query: 789 EDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRL----AVLMDHDRVVEKQLLEI 844 + + L+++ D L + K + T + L N++ ++ +D + ++K+L ++ Sbjct: 1139 QIQIGELQKEIDVLNQTKSKLSKEVDDITNENITLKNQINTTFSMSIDENNELKKKLNQL 1198 Query: 845 EHENK--ELQKKNQILLEENQNLQISLSDMQ---------QHYN---ALVEKANRT-DLA 889 EN +LQ + E+ +LQ +SD++ + YN A +EK T D Sbjct: 1199 IKENNSYQLQLNQSVPKEDFIDLQNKISDLENELQNSVSLKDYNESQAYLEKTMSTVDNL 1258 Query: 890 ESESTKYQTQLRDLESNLKRITHEH---QTLIVQKKKEIEDLEIEFNTQIESAIRDKKVL 946 +S Q +L++++ + + Q + K EI DL+ E N+Q+E I D L Sbjct: 1259 KSSVKVAQKELQNMKQTMNNQNTKMTSLQNTLQDKDSEISDLK-EKNSQLELKIED---L 1314 Query: 947 NEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLE-------LIDKHVQKQQTQ 999 + K+ E + + Q++ ++ IEN+ + E +N E L K Q + Q Sbjct: 1315 EGEKSKDNEKMKNKDLQIKLMESTIENMKSQLNESQSLNNEYALLQSTLQSKENQFSKLQ 1374 Query: 1000 SPDYTEQYINE-INKLNALLKQK-DEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKL 1057 + + Q +N+ + NA +K+ + EI L + N + M++ KL + T+ Sbjct: 1375 NENVMLQTMNQNLTNENASMKENHNREIQKLQNDLQNKEFQ-EKMINSELQKLKESLTQK 1433 Query: 1058 ENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMI--IS 1115 + + R S + + K N +++ L E K+LKET L E I K + I I+ Sbjct: 1434 DLQISNLSRYSNE-NELKNKNIQIEYLTNEN----KKLKETNLDLESQIRKKDNEINDIN 1488 Query: 1116 STIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKI 1175 S ++ + + K E + E + L++ +K + + Sbjct: 1489 SNLKRKENQLQETENTNRNLQNDIKR-KQNENNDLENEINKLKDLLSKSQHDNDLVNNDL 1547 Query: 1176 IQLETLNTELTGHDVVNQEQINQLKSKLEQLNTEN----------DNLLSTVAELRSSIS 1225 + + N +L +++ ++L+ L ++ ++N +N L E+ +S+S Sbjct: 1548 KRKDLQNRDLENKLKNLKDKSSELQLSLSRMESDNKRKDNQIIELENDLKKSKEINNSLS 1607 Query: 1226 SAVDQRGFEIAELWKQH---LAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEE 1282 + + ++ +I+EL Q L +++ + +E + L +K E DS+ S + Sbjct: 1608 NDLKRKENQISELQNQQNTDLIKKQNENNDLMNENK-SLKELIAKKESENDSINSELKRR 1666 Query: 1283 TNKIVTME-QVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXX 1341 T +I +E ++ L +K D+ L N + D+I++ E + I +E Sbjct: 1667 TLQINDLEKEIKDLASKRVDENNDLSNQIKNMKDLISKKETENNSINNELRRVNSQNNDL 1726 Query: 1342 XXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAK 1401 ++ N K++ ++ ++ + N++ + + ++ + K Sbjct: 1727 KELLAKKESEINAINNELKRISSEN-NDLKDINSKSENNYQDQLKNLKNQLTQLKNENQK 1785 Query: 1402 VLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAI 1461 +++ + + + K ++ + + +L +N++ N + ++ + I+ EKE++ ++ Sbjct: 1786 LMKSSTEEKNKLKDLINEKNIQIQSLQSKNEDLVNNQSKINNKLESIQKDLDEKENQNSV 1845 Query: 1462 LRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNE 1521 L + EN E +Q E + + I+ L+ K TE +++ N++L ++ N+ Sbjct: 1846 L---ISEN----EKLQNELMSSKTE-IQTLDQKETEFNDKLREMERNNRSLSSQI---ND 1894 Query: 1522 MQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKEL 1580 ++ L N ++DE T L+ ++ S+ QK + K R ++ +N + ++ Sbjct: 1895 LKEKLNNLTETNEKISDENTKLKQQMKIESANNQKQLKQLETEKLNRLQEENNKLKSQI 1953 Score = 172 bits (419), Expect = 6e-41 Identities = 298/1465 (20%), Positives = 632/1465 (43%), Gaps = 139/1465 (9%) Query: 147 LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINE-KDQIIEAKNKATTXXXXXXXXXXX 205 L N K + LQ ++ ++ T L +++++ ++ I KN+ T Sbjct: 1131 LQNNDKLHQIQIGELQKEIDVLNQTKSKLSKEVDDITNENITLKNQINTTFSMSIDENNE 1190 Query: 206 XXXXXXEDTKQQMT-KMQENFIAMEAEWKDEKQRLLKDIESK---DVRISSLEEANKLLE 261 + K+ + ++Q N + ++ D Q + D+E++ V + E+ LE Sbjct: 1191 LKKKLNQLIKENNSYQLQLNQSVPKEDFID-LQNKISDLENELQNSVSLKDYNESQAYLE 1249 Query: 262 AARFEI-SLEHS-KLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGS---L 316 + +L+ S K+AQ+ Q + +++ E ++++EK S L Sbjct: 1250 KTMSTVDNLKSSVKVAQKELQNMKQTMNNQNTKMTSLQNTLQDKDSEISDLKEKNSQLEL 1309 Query: 317 EIANMT-ELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSG 375 +I ++ E +K E +++ + QI+ +EN + + + + S L S++ Sbjct: 1310 KIEDLEGEKSKDNEKMKNKDLQIKLMESTIENMKSQLNESQSLNNEYALLQSTLQSKE-- 1367 Query: 376 RNTASKMKSPWSQLSSETLNQD-TDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTX 434 N SK+++ + +T+NQ+ T++ + E E IQ L DL +KE+ ++ Sbjct: 1368 -NQFSKLQN--ENVMLQTMNQNLTNENASMKENHNRE--IQKLQNDLQNKEFQEKMINSE 1422 Query: 435 XXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIK 494 KD I+ L ++ I + T + ++ + L+ ++ K Sbjct: 1423 LQKLKESLTQKDLQISNLSRYSNENELKNKNIQIEYLTNENKKLKETNLDLESQIRK--K 1480 Query: 495 DVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLK-QMQKTIDNFSKVSDS 553 D + D+ LK E Q+ Q + + +N IK K N L+ ++ K D SK Sbjct: 1481 DNEINDINSNLKRKENQL-QETENTNRNLQNDIKRKQNENNDLENEINKLKDLLSKSQHD 1539 Query: 554 N----KEIVRLTEELHHLSQKVAELEEEKGNLQLHL--VDYDSGRM------IESDVYKK 601 N ++ R + L K+ L+++ LQL L ++ D+ R +E+D+ KK Sbjct: 1540 NDLVNNDLKRKDLQNRDLENKLKNLKDKSSELQLSLSRMESDNKRKDNQIIELENDL-KK 1598 Query: 602 MIEMENLAETRLKA----ISLLESQK-FDLVQ---ELHILQQKYDEVEDKLADISQLQSD 653 E+ N LK IS L++Q+ DL++ E + L + +++ +A + ++D Sbjct: 1599 SKEINNSLSNDLKRKENQISELQNQQNTDLIKKQNENNDLMNENKSLKELIAK-KESEND 1657 Query: 654 QVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNY 713 + SE+K L QI+ L K+LA + D +KDL + KE N + N Sbjct: 1658 SINSELKRRTL--QINDLEKEIKDLASKRVDENNDLSNQIKNMKDLISKKETENNSINNE 1715 Query: 714 IQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSK 773 ++ + L+++ A+K SE+ A IN+E + +I ++ DL N +SE + Sbjct: 1716 LRRVNSQNNDLKELLAKKESEINA-INNELK-RISSE--------NNDLKDINSKSE-NN 1764 Query: 774 YKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDH 833 Y+ ++ L+ + +++ L + + + + L++ +E IQ L ++ L+++ Sbjct: 1765 YQDQLKNLKNQLTQLKNENQKLMKSSTEEKNKLKD---LINEKNIQIQSLQSKNEDLVNN 1821 Query: 834 DRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESES 893 + +L I+ + E + +N +L+ EN+ LQ N L+ + + Sbjct: 1822 QSKINNKLESIQKDLDEKENQNSVLISENEKLQ----------NELMSSKTEIQTLDQKE 1871 Query: 894 TKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLE--IEFNTQIESAIRDKKVLNEKYE 951 T++ +LR++E N + ++ + L + E E + NT+++ ++ + N+K Sbjct: 1872 TEFNDKLREMERNNRSLSSQINDLKEKLNNLTETNEKISDENTKLKQQMKIESANNQKQL 1931 Query: 952 KNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEI 1011 K +E T+ +LQE N +++ +++K + +L + +QT + D E +N+ Sbjct: 1932 KQLE--TEKLNRLQEENNKLKS------QISKKDSDLQKLKQESEQTIN-DLKESLLNKE 1982 Query: 1012 NKLNALLKQKD---EEIIALNQKIN-NAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRV 1067 L+ L K D ++I ++ IN N+Q+ + + K+ Q +N ++Q Sbjct: 1983 ESLSILEKSADFITKQIDGKSKSINENSQI-----IEQMQEKIIQ----KDNATTDLQNK 2033 Query: 1068 SKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANN 1127 KQL Q NE+ +D++K+L+ ++ I E I+ ++++ N+ Sbjct: 2034 IKQLESQLQQNEK-------DNDKVKQLQTELKEHQLKIKNLEEKIVK-----LNNENNS 2081 Query: 1128 VDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTG 1187 + + +++E+ Q ++ + E AK T + I +L + N L Sbjct: 2082 LQKL----------INSKDDEKVKQLQNNINENEAKTKTFEDQ----IQKLTSENNSLRK 2127 Query: 1188 HDVVNQEQINQLKSKLEQL-NTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQR 1246 + N ++ + +++ L N +ND + S+ +++ S+ +Q E+ + + + Sbjct: 2128 NINENDSKVKSYQEEIQNLTNEKNDLIKSSETKIKELTESSKNQIS-ELNQRLQDVTRKS 2186 Query: 1247 EADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHL 1306 + D QK E E+++ ++QLL+S Q + + Q+ +N L + Sbjct: 2187 DLDLQKKEMEIQIANKNISDLHQQLLESNQKLNEIKLQANNQQLQLKQKENDLTTANSII 2246 Query: 1307 RNLQEKYADVINQIEIL-------RSEI---EDEKVAFXXXXXXXXXXXXXXXXDLRTEN 1356 L+ + + +N+ IL + EI E+++ + +TE Sbjct: 2247 ETLKNEIENTMNKSSILVQNEMNKKDEIIQNLQEQLSNLKQETNEEISKLQNDKNNQTEL 2306 Query: 1357 QSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRV--NDAEAKVLELTHQLELKDS 1414 + + + I N+ E N Q + + ND + + + + Sbjct: 2307 LNLIKSKNDEINNLKEINRQKDQQIMDLKRYEQTELLNLSNNDDQNRSSSIVYNSSTLMK 2366 Query: 1415 EIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYE 1474 + Q + I +D+ +++ Q E K +++ EK+ ++ L +++ +++ Sbjct: 2367 SLRQVKEDSQIREKFIDDQLKSLSMQKDEEIKNLQNKNSEKDEKIRDLEKQINNLSDNSN 2426 Query: 1475 TMQKESEIERVKL---IEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEI 1531 +++ES I VKL I+ +N KI + + + Q+ + N+ L + K N+ E + Sbjct: 2427 HIKEESMINEVKLKSNIDSMNDKILQMQNDSNQLFKENQNLRNSIDKLNKQIKDFEQENE 2486 Query: 1532 EIVTLNDEITNLQNMVRASSSKIQK 1556 + T L N + + KI K Sbjct: 2487 SLKQTIQSFTKLNNELTEENEKIYK 2511 Score = 169 bits (412), Expect = 4e-40 Identities = 318/1546 (20%), Positives = 663/1546 (42%), Gaps = 176/1546 (11%) Query: 168 METTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIA 227 +E+ DL EK N+ +I K E ++ +M+ N + Sbjct: 1829 LESIQKDLDEKENQNSVLISENEKLQNELMSSKTEIQTLDQKETE-FNDKLREMERNNRS 1887 Query: 228 MEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXX 287 + ++ D K++L E+ + +IS +E KL + ++ +E + ++L+Q Sbjct: 1888 LSSQINDLKEKLNNLTETNE-KIS--DENTKLKQ----QMKIESANNQKQLKQLETEKLN 1940 Query: 288 XXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTE-LTKKIELLEHLNCQIRQTNKELE 346 K I + +++++ I ++ E L K E L L K+++ Sbjct: 1941 RLQEENNKLKSQISKKDSDLQKLKQESEQTINDLKESLLNKEESLSILEKSADFITKQID 2000 Query: 347 NKLATMGTESKAVSSPSKKGSPLISRKSGRNT--ASKMKSPWSQLSSETLNQD------T 398 K ++ S+ + +K I +K T +K+K SQL + D T Sbjct: 2001 GKSKSINENSQIIEQMQEK----IIQKDNATTDLQNKIKQLESQLQQNEKDNDKVKQLQT 2056 Query: 399 DKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQ 458 + K ++ +I LE I LN + + +I+ KD ++ + + Q Sbjct: 2057 ELKEHQLKIKNLEEKIVKLNNENNSLQKLINSKDDEKVKQLQNNINENEAKTKTFEDQIQ 2116 Query: 459 HM--EGPSLI-HVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQL 515 + E SL ++ N V + + L E ND IK K + E +S++ QI++L Sbjct: 2117 KLTSENNSLRKNINENDSKVKSYQEEIQNLTNEKNDLIKSSETK-IKELTESSKNQISEL 2175 Query: 516 NDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHL----SQKV 571 N + + KS+ L+ K+M+ I N +SD +++++ ++L+ + + + Sbjct: 2176 NQRLQDVTR-----KSDLDLQKKEMEIQIAN-KNISDLHQQLLESNQKLNEIKLQANNQQ 2229 Query: 572 AELEEEKGNL------------QLHLVDYDSGRMIESDVYKKMIEMENLAE--TRLKA-- 615 +L++++ +L ++ S ++++++ KK ++NL E + LK Sbjct: 2230 LQLKQKENDLTTANSIIETLKNEIENTMNKSSILVQNEMNKKDEIIQNLQEQLSNLKQET 2289 Query: 616 ---ISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDAL- 671 IS L++ K + + L++++ K DE+ + L +I++ Q DQ ++K E ++ Sbjct: 2290 NEEISKLQNDKNNQTELLNLIKSKNDEINN-LKEINR-QKDQQIMDLKRYEQTELLNLSN 2347 Query: 672 --------------SASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQEN 717 S K L V E+ ++ ++ + +K L K++ + LQN E Sbjct: 2348 NDDQNRSSSIVYNSSTLMKSLRQVKEDSQIREKFIDDQLKSLSMQKDEEIKNLQNKNSEK 2407 Query: 718 MDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSR 777 + LEK +I+ L NH ++ + + + + I + I ++++ ++ Sbjct: 2408 DEKIRDLEK----QINNLSDNSNHIKEESMINEVKLKSNIDSMNDKILQMQNDSNQLFKE 2463 Query: 778 ICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVV 837 L SI + + E++ + L +Q K +E T + +++ + L++++ V Sbjct: 2464 NQNLRNSIDKLNKQIKDFEQENESLKQTIQSFTKLNNELTEENEKIYKKYNDLINNNAVN 2523 Query: 838 EKQLLEIEHENKELQKKNQI-LLEENQNLQISLSDMQQHYNALVEKANRTDLAESEST-- 894 E L ++ +N KNQI +LE +NL++S + Q+ + + E TDLAE E Sbjct: 2524 ENNLQVMKDQNN----KNQIKILELTRNLEMSKFNDDQNKDKINEL--ETDLAEKEKLIK 2577 Query: 895 --KYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNT----QIESAIRDKKVLNE 948 + Q + + ++K+I + I + + +++ N + E+ + ++LN+ Sbjct: 2578 LLQNQLTVSSSDKDMKQILQQKDEEIRKLNENNGKIKVLQNQIEKMKEENNSKTNELLNQ 2637 Query: 949 KYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLEL--IDKHVQKQQTQSPDYTEQ 1006 E + ++ LEA+ ++ + I NLN++ L M ++ + + K Q+Q D Sbjct: 2638 LKESENKRIS-LEAEKKKLEIEISNLNIDDNNLKLMEQKMKEMSNVINKLQSQESDKDRT 2696 Query: 1007 YINE---INKL-------------NALLKQKDEEIIALNQKINNAQVS----YMSMVSDY 1046 +N+ I KL N LL+ + ++ + +I++A ++ MS +S Sbjct: 2697 IMNQTKQIKKLGSIMTKAKSLKAENTLLRSQISDLESSKTEISSASLNSSSPQMSSLSQK 2756 Query: 1047 E--SKLAQFTTKL--ENMEEEMQRVSKQLLDSKQ---HNEELQILVREQDDQIKELKETK 1099 + S+L + T+L EN + +M+ + K D NE+LQ+ ++ + Q+ ++KE + Sbjct: 2757 KKISRLEKQVTELLQENEDLKMEIIHKSTSDENLDSLENEKLQLRIKSLETQLNKMKEIE 2816 Query: 1100 LTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLK-VQEEEEFIQERSVLQ 1158 N+ KT+ + + +S + ++ LK ++E E +++ S + Sbjct: 2817 -NENKNL-KTKVSFMEENSKKLSSEIESLIKKNGEMKINLVSLKSIKENFEILEKSSKER 2874 Query: 1159 EQS-----AKLNTELQECYTKIIQLETLNTELTGHDVVN----QEQINQLKSKLEQLNTE 1209 E A ++ + TK+ LE ++L + +N Q+ N LK K QL Sbjct: 2875 EAEYSKYRASQEKKVNDLQTKLSTLENDYSDLKNENEMNVLEIQKITNNLKLKENQLQRS 2934 Query: 1210 NDN---------LLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQ 1260 DN L+T +S+ + R EI +L K + + D ++ + V Sbjct: 2935 LDNDKTMDSLQATLNTKTSENQKLSTELVLRNNEIKDL-KDEIGKVNNDKEELMKIINVN 2993 Query: 1261 LSAFESKYEQLLD---SVQSSTQE-ETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADV 1316 + + + LLD ++ +E + NK +++ K+ + ++ ++E + Sbjct: 2994 NTLVQKLQKDLLDRNNQIEFLNKEIQENKEEFDQKINESNTKIDELNNIIKQMKETIKSL 3053 Query: 1317 INQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQ 1376 N + L+S IE + L EN+ + E++ I + Sbjct: 3054 SNDKDNLKSTIEGNEDEIHRIANKLQKKSNKINFIL-AENEKLQNEIEKNNKEIENLRKK 3112 Query: 1377 LKKSSXXXXXXXXXXXXRV-------NDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQ 1429 LK + + ND + + EL++QL+LK+ E ++ E+ + + Q Sbjct: 3113 LKSNEEKLNNQQKESKSSIQNHLQINNDLKKENEELSNQLKLKEDEKQKQNEEFDLKIKQ 3172 Query: 1430 RNDEFENVRQQLVEYEKRIED----LTYEKE---SELAILRLKMHENANHYETMQKE--- 1479 + +E ++ ++ + + E+ + EKE E L K+ E + E + K+ Sbjct: 3173 KEEEISKLKDEISNLQNKKEEANQNIINEKEELIKENGDLHHKIDELQTNIEDLNKKLIS 3232 Query: 1480 SEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQ---TALENQ--EIEIV 1534 S+ E K+I +L + ES+ K A+L + ++ K NE + LEN+ + +I Sbjct: 3233 SQRENEKIINKLKKDLEESIKSQKVQAKLINHRDNKL-KENEKEVHSVLLENEILKSDIK 3291 Query: 1535 TLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKEL 1580 ++EI L S+S ++ A+D+ D Q +N + K++ Sbjct: 3292 KKSNEIDRLNKQYLTSTS-----ITLANDSNL-FDRQANNDLQKQI 3331 Score = 164 bits (399), Expect = 2e-38 Identities = 278/1437 (19%), Positives = 609/1437 (42%), Gaps = 113/1437 (7%) Query: 164 KMKIMETTILDLQEKINE---KDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTK 220 ++KI+E T K N+ KD+I E + + +Q+ + Sbjct: 2538 QIKILELTRNLEMSKFNDDQNKDKINELETDLAEKEKLIKLLQNQLTVSSSDKDMKQILQ 2597 Query: 221 MQENFIAMEAEWKDEKQRLLKDIES-KDVRISSLEEA-NKLLEAARFEISLEHSKLAQEL 278 ++ I E + + L IE K+ S E N+L E+ ISLE K E+ Sbjct: 2598 QKDEEIRKLNENNGKIKVLQNQIEKMKEENNSKTNELLNQLKESENKRISLEAEKKKLEI 2657 Query: 279 EQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQI 338 E + + + E I N T+ KK+ + + Sbjct: 2658 EISNLNIDDNNLKLMEQKMKEMSNVINKLQSQESDKDRTIMNQTKQIKKLGSIMTKAKSL 2717 Query: 339 RQTNKELENKLATMGTESKAVSSPS-KKGSPLISRKSGRNTASKMKSPWSQLSSET---- 393 + N L ++++ + + +SS S SP +S S + S+++ ++L E Sbjct: 2718 KAENTLLRSQISDLESSKTEISSASLNSSSPQMSSLSQKKKISRLEKQVTELLQENEDLK 2777 Query: 394 ---LNQDT-DKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLI 449 +++ T D+ ++ E KL++ I+SL L + + +E L Sbjct: 2778 MEIIHKSTSDENLDSLENEKLQLRIKSLETQLNKMKEIENENKNLKTKVSFMEENSKKLS 2837 Query: 450 AQLQLEHQQHMEGP-SLIHVGTNTEDVNEIAKVQEQLKQELND--EIKDVNVKDLIEKLK 506 ++++ +++ E +L+ + + E+ + K ++ + E + ++ V DL KL Sbjct: 2838 SEIESLIKKNGEMKINLVSLKSIKENFEILEKSSKEREAEYSKYRASQEKKVNDLQTKLS 2897 Query: 507 SAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHH 566 + E + L +E + + K+ +N KLK Q+Q+++DN + + T E Sbjct: 2898 TLENDYSDLKNENEMNVLEIQKITNNLKLKENQLQRSLDNDKTMDSLQATLNTKTSENQK 2957 Query: 567 LSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDL 626 LS ++ E +L+ + ++ + + K+I + N +L+ L + + + Sbjct: 2958 LSTELVLRNNEIKDLKDEIGKVNN----DKEELMKIINVNNTLVQKLQKDLLDRNNQIEF 3013 Query: 627 VQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLK 686 + + +Q+ +E + K+ + S + D++ + IK ++E I +LS K L IE + Sbjct: 3014 LNKE--IQENKEEFDQKINE-SNTKIDELNNIIKQ--MKETIKSLSNDKDNLKSTIEGNE 3068 Query: 687 LDKEQLYGTIKDLENDKEDIM---NKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEE 743 + ++ ++ N I+ KLQN I++N + L K + E L E Sbjct: 3069 DEIHRIANKLQKKSNKINFILAENEKLQNEIEKNNKEIENLRK-KLKSNEEKLNNQQKES 3127 Query: 744 QSKIQTQFGIDAKIQERDLYIENIESELS-KYKSRICRLEESIAVMEDRRYSLERKADQL 802 +S IQ I+ +++ + E + ++L K + + EE ++ + + + D++ Sbjct: 3128 KSSIQNHLQINNDLKKEN---EELSNQLKLKEDEKQKQNEEFDLKIKQKEEEISKLKDEI 3184 Query: 803 GSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKEL---QKKNQILL 859 + +K++A +++EL+ L H ++ E Q IE NK+L Q++N+ ++ Sbjct: 3185 SNLQNKKEEANQNIINEKEELIKENGDL--HHKIDELQT-NIEDLNKKLISSQRENEKII 3241 Query: 860 EE-NQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLI 918 + ++L+ S+ + + + N+ E E + L+S++K+ Sbjct: 3242 NKLKKDLEESIKSQKVQAKLINHRDNKLKENEKEVHSVLLENEILKSDIKK--------- 3292 Query: 919 VQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNV 978 K EI+ L ++ T + + L ++ N + Q+E+ + + +NL Sbjct: 3293 --KSNEIDRLNKQYLTSTSITLANDSNLFDRQANN-DLQKQIESLQNQNQMLTQNLTRMR 3349 Query: 979 EELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDE------EIIALNQKI 1032 EE+++ N E+I+ ++ +TQ D ++ N +NK +L+ K+E EI ++ Sbjct: 3350 EEIDQRNTEIIEIKRERTETQINDNSQLKENLLNKEKEILRLKNENQELIKEITDKTLRL 3409 Query: 1033 NNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQI 1092 + + +++ + KL +E E + + ++L ++ NE++ ++ +DD+I Sbjct: 3410 SEVEKNFLKQTISSKDYEMSMKPKLLELEAENKSLKEELNANEVDNEKI---LKLKDDEI 3466 Query: 1093 KELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQ 1152 L++ K + I E + + + + + L +E Sbjct: 3467 NNLQKAKGDLNLKIVAMENSQKINEKKKVKEIILKLQKMEVENKDLTNRLNDLMKENEDL 3526 Query: 1153 ERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKS---KLEQLNTE 1209 +R++ K TE E K+ +++ N ++ + ++++N+ +S KL + E Sbjct: 3527 KRNISDLMKGKSLTE--ELNKKLDEIKRSNIAISTELEITKQKLNKEESSKRKLMKKIEE 3584 Query: 1210 NDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYE 1269 +L+ + E S+ + + + +I E + + E QK E +L + + E K Sbjct: 3585 QKSLIKKLNEENDSLKKSEEDKIGKIKENENNLILETEKSKQK-EEDLLKKNNDLEKKLL 3643 Query: 1270 QLLDSVQSSTQEETNKIVTME-QVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIE 1328 + ++ ++ ++I ++ ++ L +D+ + + NL + + + N I L +I+ Sbjct: 3644 EYQKNIAELNEKHKHEIDLLQSKINDLTKFKEDQTKEITNLNQIISQLKNDILKLNQQID 3703 Query: 1329 DEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXX 1388 D F DL+ + K E L E +L + Sbjct: 3704 DLNQKFNEKQKECEQIET----DLKQKEVKNKSQTE---LQFEAEKKKLVE--------- 3747 Query: 1389 XXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRI 1448 +++ +++ LT+ + K E QK + L + N+E+++ R +YE +I Sbjct: 3748 -----QISSLNNEIMSLTND-KAKLEEDQQKLIK---KLKKLNEEYQSKRS---DYEFQI 3795 Query: 1449 EDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAEL 1508 + +T E E+ L++ + + N E ++ E+ E++ I + K E L K +++L Sbjct: 3796 KTITNNYEDEIQKLKVTIKKLENELELLKIEN--EKINGILQAREKTNE--KLRKSISDL 3851 Query: 1509 NKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSS----KIQKHVSFA 1561 + ++ +K NEM ++ I L E+ +L+N + +SS K++K+ A Sbjct: 3852 RDSSNDD-SKYNEM-------KLTIAKLKSELNSLRNQSKENSSISDDKLEKYKQIA 3900 Score = 160 bits (388), Expect = 3e-37 Identities = 285/1490 (19%), Positives = 638/1490 (42%), Gaps = 118/1490 (7%) Query: 145 THLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXX 204 T L N IK K++ ++ L+ + + I+DL K E+ +++ N Sbjct: 2304 TELLNLIKSKNDEINNLKEINRQKDQQIMDL--KRYEQTELLNLSNNDDQNRSSSIVYNS 2361 Query: 205 XXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAAR 264 K+ ++++E FI + + + KD E K+++ + E+ K+ + + Sbjct: 2362 STLMKSLRQVKED-SQIREKFIDDQLK----SLSMQKDEEIKNLQNKNSEKDEKIRDLEK 2416 Query: 265 FEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTEL 324 +I+ E+ + + ++ + +E +L ++ +L Sbjct: 2417 -QINNLSDNSNHIKEESMINEVKLKSNIDSMNDKILQMQNDSNQLFKENQNLR-NSIDKL 2474 Query: 325 TKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKS-GRNTASKMK 383 K+I+ E N ++QT + + E++ + KK + LI+ + N MK Sbjct: 2475 NKQIKDFEQENESLKQTIQSFTKLNNELTEENEKIY---KKYNDLINNNAVNENNLQVMK 2531 Query: 384 SPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXX 443 ++ + L + +++K + + I L DL +KE +I Sbjct: 2532 DQNNKNQIKILELTRNLEMSKFNDDQNKDKINELETDLAEKEKLIKLLQNQLTVSSSDKD 2591 Query: 444 GKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIE 503 K ++ Q E ++ E I V N +I K++E+ + N+ + + K+ Sbjct: 2592 MKQ-ILQQKDEEIRKLNENNGKIKVLQN-----QIEKMKEENNSKTNELLNQL--KESEN 2643 Query: 504 KLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNF-SKVSDSNKEIVRLTE 562 K S E + +L EI N + +K + K+K+M I+ S+ SD ++ I+ T+ Sbjct: 2644 KRISLEAEKKKLEIEISNLNIDDNNLKLMEQ-KMKEMSNVINKLQSQESDKDRTIMNQTK 2702 Query: 563 ELHHLSQ---KVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLL 619 ++ L K L+ E L+ + D +S + S + + ++ K IS L Sbjct: 2703 QIKKLGSIMTKAKSLKAENTLLRSQISDLESSKTEISSASLNSSSPQMSSLSQKKKISRL 2762 Query: 620 ESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLE-EQIDALSASKKEL 678 E Q +L+QE L+ + ++ L+++++ IKS+ + ++ + K L Sbjct: 2763 EKQVTELLQENEDLKMEIIHKSTSDENLDSLENEKLQLRIKSLETQLNKMKEIENENKNL 2822 Query: 679 ALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNY--IQENMDLTDKLEKMSAEKISELL 736 + ++ + ++L I+ L ++ L + I+EN ++ +K K + S+ Sbjct: 2823 KTKVSFMEENSKKLSSEIESLIKKNGEMKINLVSLKSIKENFEILEKSSKEREAEYSKYR 2882 Query: 737 AKINHEEQSKIQTQFGIDAKIQERDLYIENIES--ELSKYKSRICRLEESIAVMEDRRYS 794 A ++ + +QT+ + DL EN + E+ K + + E + D + Sbjct: 2883 AS-QEKKVNDLQTKLST-LENDYSDLKNENEMNVLEIQKITNNLKLKENQLQRSLDNDKT 2940 Query: 795 LERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKK 854 ++ L + E QK +E ++ +E+ + + + E+ + I N +QK Sbjct: 2941 MDSLQATLNTKTSENQKLSTELVLRNNEIKDLKDEIGKVNNDKEELMKIINVNNTLVQKL 3000 Query: 855 NQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEH 914 + LL+ N ++ ++Q++ +K N ++ E Q+++ +L Sbjct: 3001 QKDLLDRNNQIEFLNKEIQENKEEFDQKINESNTKIDELNNIIKQMKETIKSLSNDKDNL 3060 Query: 915 QTLIVQKKKEIEDLEIEF---NTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNI 971 ++ I + EI + + + +I + + + L + EKN + + L +L K+N Sbjct: 3061 KSTIEGNEDEIHRIANKLQKKSNKINFILAENEKLQNEIEKNNKEIENLRKKL---KSNE 3117 Query: 972 ENLNMNVEELNKMNLE---LIDKHVQKQQTQSPDYTEQYINEINKLNA----LLKQKDEE 1024 E LN N ++ +K +++ I+ ++K+ + + + +E K N +KQK+EE Sbjct: 3118 EKLN-NQQKESKSSIQNHLQINNDLKKENEELSNQLKLKEDEKQKQNEEFDLKIKQKEEE 3176 Query: 1025 IIALNQKINNAQ----VSYMSMVSDYESKLAQ---FTTKLENMEEEMQRVSKQLLDSKQH 1077 I L +I+N Q + +++++ E + + K++ ++ ++ ++K+L+ S++ Sbjct: 3177 ISKLKDEISNLQNKKEEANQNIINEKEELIKENGDLHHKIDELQTNIEDLNKKLISSQRE 3236 Query: 1078 NEEL-QILVREQDDQIKELK---------ETKLTF---EMNIPKTEGMIISSTIEPMSDD 1124 NE++ L ++ ++ IK K + KL E++ E I+ S I+ S++ Sbjct: 3237 NEKIINKLKKDLEESIKSQKVQAKLINHRDNKLKENEKEVHSVLLENEILKSDIKKKSNE 3296 Query: 1125 ANNVDXXXXXXXXXXXXLK-----------VQEEEEFIQERS-VLQEQSAKLNTELQECY 1172 + ++ +Q++ E +Q ++ +L + ++ E+ + Sbjct: 3297 IDRLNKQYLTSTSITLANDSNLFDRQANNDLQKQIESLQNQNQMLTQNLTRMREEIDQRN 3356 Query: 1173 TKIIQL--ETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAE--LRSS----- 1223 T+II++ E T++ + + + +N+ K L +L EN L+ + + LR S Sbjct: 3357 TEIIEIKRERTETQINDNSQLKENLLNKEKEIL-RLKNENQELIKEITDKTLRLSEVEKN 3415 Query: 1224 -ISSAVDQRGFEIAELWKQHLAQREADFQKTEHELR---VQLSAFESKYEQLLDSVQSST 1279 + + + +E++ K L + EA+ + + EL V + ++++Q + Sbjct: 3416 FLKQTISSKDYEMS--MKPKLLELEAENKSLKEELNANEVDNEKILKLKDDEINNLQKAK 3473 Query: 1280 QEETNKIVTMEQVTSLQNKLQDKEE--HLRNLQEKYADVINQIEILRSEIEDEK--VAFX 1335 + KIV ME + K + KE L+ ++ + D+ N++ L E ED K ++ Sbjct: 3474 GDLNLKIVAMENSQKINEKKKVKEIILKLQKMEVENKDLTNRLNDLMKENEDLKRNISDL 3533 Query: 1336 XXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKK--SSXXXXXXXXXXXX 1393 +++ N + E + +N+E + +K Sbjct: 3534 MKGKSLTEELNKKLDEIKRSNIAISTELEITKQKLNKEESSKRKLMKKIEEQKSLIKKLN 3593 Query: 1394 RVNDAEAKVLE-LTHQLELKDSEIY---QKTHEYTITLTQRNDEFENVRQQLVEYEKRIE 1449 ND+ K E +++ ++ + +K+ + L ++N++ E ++L+EY+K I Sbjct: 3594 EENDSLKKSEEDKIGKIKENENNLILETEKSKQKEEDLLKKNNDLE---KKLLEYQKNIA 3650 Query: 1450 DLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELN 1509 +L + + E+ +L+ K+++ E KE ++I +L I + LN+Q+ +LN Sbjct: 3651 ELNEKHKHEIDLLQSKINDLTKFKEDQTKEIT-NLNQIISQLKNDI---LKLNQQIDDLN 3706 Query: 1510 KALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVS 1559 + E+ + +++T L+ +E++ N T LQ A K+ + +S Sbjct: 3707 QKFNEKQKECEQIETDLKQKEVK----NKSQTELQ--FEAEKKKLVEQIS 3750 Score = 147 bits (355), Expect = 3e-33 Identities = 291/1514 (19%), Positives = 632/1514 (41%), Gaps = 152/1514 (10%) Query: 102 EILMEKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNALSVL 161 ++L +I++ KE + + ++ + +SN + DN L ++ Sbjct: 2614 KVLQNQIEKMKEENNSKTNELLNQLKESENKRISLEAEKKKLEIEISN-LNIDDNNLKLM 2672 Query: 162 QVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKM 221 + KMK M I LQ + ++KD+ I + K + K + T + Sbjct: 2673 EQKMKEMSNVINKLQSQESDKDRTIMNQTKQIKKLGSIMTKA--------KSLKAENTLL 2724 Query: 222 QENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKL--LEAARFEISLEHSKLAQELE 279 + +E+ K E + S ++SSL + K+ LE E+ E+ L E+ Sbjct: 2725 RSQISDLESS-KTEISSA--SLNSSSPQMSSLSQKKKISRLEKQVTELLQENEDLKMEII 2781 Query: 280 QXXXXXXXXXXXXXX---LAKQSIEPSCEEKTEIEEKGS---LEIANMTELTKKIELLEH 333 L +S+E + EIE + +++ M E +KK+ Sbjct: 2782 HKSTSDENLDSLENEKLQLRIKSLETQLNKMKEIENENKNLKTKVSFMEENSKKLS--SE 2839 Query: 334 LNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSET 393 + I++ N E++ L ++ + + K + S + + K Q T Sbjct: 2840 IESLIKK-NGEMKINLVSLKSIKENFEILEKSSKEREAEYSKYRASQEKKVNDLQTKLST 2898 Query: 394 LNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEK-------DTXXXXXXXXXXGKD 446 L D N+NE+ LE IQ + +L KE + D+ Sbjct: 2899 LENDYSDLKNENEMNVLE--IQKITNNLKLKENQLQRSLDNDKTMDSLQATLNTKTSENQ 2956 Query: 447 TLIAQLQLEHQQHMEGPSLI-HVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKL 505 L +L L + + + I V + E++ +I V L Q+L ++ D N ++ Sbjct: 2957 KLSTELVLRNNEIKDLKDEIGKVNNDKEELMKIINVNNTLVQKLQKDLLDRN-----NQI 3011 Query: 506 KSAEEQITQLNDEIDAA-NKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTE-E 563 + ++I + +E D N++ K+ + + +KQM++TI + S D+ K + E E Sbjct: 3012 EFLNKEIQENKEEFDQKINESNTKIDELNNI-IKQMKETIKSLSNDKDNLKSTIEGNEDE 3070 Query: 564 LHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQK 623 +H ++ K L+++ + L + + +++++ K E+ENL + L +Q+ Sbjct: 3071 IHRIANK---LQKKSNKINFILAENEK---LQNEIEKNNKEIENLRKKLKSNEEKLNNQQ 3124 Query: 624 FDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIE 683 + + Q + ++ + L + +++++ +++K L+E D +E L I+ Sbjct: 3125 KESKSSI----QNHLQINNDL----KKENEELSNQLK---LKE--DEKQKQNEEFDLKIK 3171 Query: 684 NLKLDKEQLYGTIKDLENDKED----IMNKLQNYIQENMDLTDKLEKMSAEKISELLAKI 739 + + +L I +L+N KE+ I+N+ + I+EN DL K++++ I +L K+ Sbjct: 3172 QKEEEISKLKDEISNLQNKKEEANQNIINEKEELIKENGDLHHKIDELQTN-IEDLNKKL 3230 Query: 740 --NHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLER 797 + E KI + D E + + ++++L ++ +L+E+ E +S+ Sbjct: 3231 ISSQRENEKIINKLKKDL---EESIKSQKVQAKLINHRDN--KLKEN----EKEVHSVLL 3281 Query: 798 KADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLL-EIEHENKELQKKNQ 856 + + L S +++K + + L + L + + ++Q +++ + + LQ +NQ Sbjct: 3282 ENEILKSDIKKKSNEIDR--LNKQYLTSTSITLANDSNLFDRQANNDLQKQIESLQNQNQ 3339 Query: 857 ILLEENQNLQISLSDMQQHYNALVE-KANRTDLAESESTKYQTQLRDLESNLKRITHEHQ 915 +L QNL ++ Q ++E K RT+ +++++ + L + E + R+ +E+Q Sbjct: 3340 ML---TQNLTRMREEIDQRNTEIIEIKRERTETQINDNSQLKENLLNKEKEILRLKNENQ 3396 Query: 916 TLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIE-YVTQLEAQLQEYKNNIENL 974 LI KEI D + + ++E + + ++ YE +++ + +LEA+ + K E L Sbjct: 3397 ELI----KEITDKTLRLS-EVEKNFLKQTISSKDYEMSMKPKLLELEAENKSLK---EEL 3448 Query: 975 NMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINN 1034 N N E N+ L+L D + Q D + + N K+K +EII QK+ Sbjct: 3449 NAN-EVDNEKILKLKDDEINNLQKAKGDLNLKIVAMENSQKINEKKKVKEIILKLQKMEV 3507 Query: 1035 AQVSYMSMVSDYESKLAQFTTKLENM---EEEMQRVSKQLLDSKQHNEELQILVREQDDQ 1091 + ++D + + ++ + + ++K+L + K+ N + + + Sbjct: 3508 ENKDLTNRLNDLMKENEDLKRNISDLMKGKSLTEELNKKLDEIKRSNIAISTELEITKQK 3567 Query: 1092 IKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFI 1151 + + + +K I + + +I + +D + + E E+ Sbjct: 3568 LNKEESSKRKLMKKIEEQKSLI--KKLNEENDSLKKSEEDKIGKIKENENNLILETEKSK 3625 Query: 1152 QERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDV-VNQEQINQLKSKLEQLNTEN 1210 Q+ L +++ L +L E I +L E H++ + Q +IN L E E Sbjct: 3626 QKEEDLLKKNNDLEKKLLEYQKNIAELN----EKHKHEIDLLQSKINDLTKFKEDQTKEI 3681 Query: 1211 DNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQ 1270 NL +++L++ I Q I +L Q +++ + ++ E +L K ++ Sbjct: 3682 TNLNQIISQLKNDILKLNQQ----IDDL-NQKFNEKQKECEQIETDL---------KQKE 3727 Query: 1271 LLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDE 1330 + + Q+ Q E K +EQ++SL N++ L+E +I +++ L E + + Sbjct: 3728 VKNKSQTELQFEAEKKKLVEQISSLNNEIMSLTNDKAKLEEDQQKLIKKLKKLNEEYQSK 3787 Query: 1331 KVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNIN--EENAQLKKSSXXXXXXX 1388 + + ++T +Y+ ++ + I E +L K Sbjct: 3788 RSDY--------------EFQIKTITNNYEDEIQKLKVTIKKLENELELLKIENEKINGI 3833 Query: 1389 XXXXXRVNDAEAKVLELTHQLELKD-SEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKR 1447 + N+ K + +L+D S K +E +T+ + E ++R Q E Sbjct: 3834 LQAREKTNEKLRKSIS-----DLRDSSNDDSKYNEMKLTIAKLKSELNSLRNQSKE-NSS 3887 Query: 1448 IEDLTYEKESELAILRLKM--HENANHYETMQKESEIERVKLIEEL--NVKITESVSLNK 1503 I D EK ++A K+ + + + ++ +S E ++++ + + K+ V +K Sbjct: 3888 ISDDKLEKYKQIAKRAQKVLSYAASLREKVIETQSITECLEILNSIFVSAKLERVVLKSK 3947 Query: 1504 QVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASD 1563 + K+L+ +++ + + +V ++ I +L + V+ + + S D Sbjct: 3948 SIESPKKSLQSAISEIQRIFPCVS----AVVEPSENIHSLDDQVQV----LHQQFSLLRD 3999 Query: 1564 TKQGRDEQLDNTMN 1577 R++ +DN N Sbjct: 4000 VFDNREKTVDNLGN 4013 Score = 141 bits (342), Expect = 1e-31 Identities = 270/1464 (18%), Positives = 618/1464 (42%), Gaps = 116/1464 (7%) Query: 151 IKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXX 210 +K+K+N L+ I+ET +++ +N+ +++ + Sbjct: 2232 LKQKENDLTTAN---SIIETLKNEIENTMNKSSILVQNE---MNKKDEIIQNLQEQLSNL 2285 Query: 211 XEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEIS-L 269 ++T ++++K+Q + K+ + LL I+SK+ I++L+E N+ + ++ Sbjct: 2286 KQETNEEISKLQND--------KNNQTELLNLIKSKNDEINNLKEINRQKDQQIMDLKRY 2337 Query: 270 EHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEK---GSLEIANMTELTK 326 E ++L +S+ +E ++I EK L+ +M + + Sbjct: 2338 EQTELLNLSNNDDQNRSSSIVYNSSTLMKSLR-QVKEDSQIREKFIDDQLKSLSMQK-DE 2395 Query: 327 KIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRK--SGRNTASKMKS 384 +I+ L++ N + + ++LE ++ + S + S + S + +M++ Sbjct: 2396 EIKNLQNKNSEKDEKIRDLEKQINNLSDNSNHIKEESMINEVKLKSNIDSMNDKILQMQN 2455 Query: 385 PWSQLSSETLN-QDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISE--KDTXXXXXXXX 441 +QL E N +++ K+NK +I E +SL + + + +E ++ Sbjct: 2456 DSNQLFKENQNLRNSIDKLNK-QIKDFEQENESLKQTIQSFTKLNNELTEENEKIYKKYN 2514 Query: 442 XXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDL 501 + + + L+ + + I + T ++ +Q K ++N+ D+ K+ Sbjct: 2515 DLINNNAVNENNLQVMKDQNNKNQIKILELTRNLEMSKFNDDQNKDKINELETDLAEKEK 2574 Query: 502 IEKLKSAEEQITQLNDE----IDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEI 557 + KL + ++ + + + ++ + K+ N+ K+K +Q I+ + ++N + Sbjct: 2575 LIKLLQNQLTVSSSDKDMKQILQQKDEEIRKLNENNG-KIKVLQNQIEKMKE--ENNSKT 2631 Query: 558 VRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAIS 617 L +L K LE EK L++ + + + + +KM EM N+ S Sbjct: 2632 NELLNQLKESENKRISLEAEKKKLEIEISNLNIDDNNLKLMEQKMKEMSNVINKLQSQES 2691 Query: 618 LLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKE 677 + + +++ L + + A+ + L+S S+++S E +L++S + Sbjct: 2692 DKDRTIMNQTKQIKKLGSIMTKAKSLKAENTLLRSQ--ISDLESSKTEISSASLNSSSPQ 2749 Query: 678 LALVIENLKLDK--EQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISEL 735 ++ + + K+ + +Q+ +++ E+ K +I++K + EN+D + EK+ +I L Sbjct: 2750 MSSLSQKKKISRLEKQVTELLQENEDLKMEIIHKSTS--DENLDSLEN-EKLQL-RIKSL 2805 Query: 736 LAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSL 795 ++N ++ + + + + K+ + + + SE+ + ++ ++ ++ S+ Sbjct: 2806 ETQLNKMKEIENENK-NLKTKVSFMEENSKKLSSEIESLIKKNGEMKINLVSLK----SI 2860 Query: 796 ERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENK----EL 851 + + L +E++ YS+Y +++ VN L + +E ++++EN+ E+ Sbjct: 2861 KENFEILEKSSKEREAEYSKYRASQEKKVNDLQTKLS---TLENDYSDLKNENEMNVLEI 2917 Query: 852 QK-KNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRI 910 QK N + L+ENQ LQ SL D + ++L N SE+ K T+L + +K + Sbjct: 2918 QKITNNLKLKENQ-LQRSL-DNDKTMDSLQATLNTKT---SENQKLSTELVLRNNEIKDL 2972 Query: 911 THEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVT-QLEAQLQEYKN 969 E + K++ ++ + + NT ++ +D N + IE++ +++ +E+ Sbjct: 2973 KDEIGKVNNDKEELMKIINVN-NTLVQKLQKDLLDRNNQ----IEFLNKEIQENKEEFDQ 3027 Query: 970 NIENLNMNVEELNKMNLELID--KHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEI-- 1025 I N ++ELN + ++ + K + + E +EI+++ L++K +I Sbjct: 3028 KINESNTKIDELNNIIKQMKETIKSLSNDKDNLKSTIEGNEDEIHRIANKLQKKSNKINF 3087 Query: 1026 -IALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLL----DSKQHNEE 1080 +A N+K+ N + + KL KL N ++E + + L D K+ NEE Sbjct: 3088 ILAENEKLQNEIEKNNKEIENLRKKLKSNEEKLNNQQKESKSSIQNHLQINNDLKKENEE 3147 Query: 1081 LQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXX 1140 L ++ ++D+ ++ E F++ I + E I + D+ +N+ Sbjct: 3148 LSNQLKLKEDEKQKQNEE---FDLKIKQKE-----EEISKLKDEISNLQNK--------- 3190 Query: 1141 XLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLK 1200 K + + I E+ L +++ L+ ++ E T I E LN +L N++ IN+LK Sbjct: 3191 --KEEANQNIINEKEELIKENGDLHHKIDELQTNI---EDLNKKLISSQRENEKIINKLK 3245 Query: 1201 SKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHEL-RV 1259 LE E+ A+L + + + + E+ + ++ + +D +K +E+ R+ Sbjct: 3246 KDLE----ESIKSQKVQAKLINHRDNKLKENEKEVHSVLLENEILK-SDIKKKSNEIDRL 3300 Query: 1260 QLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQ 1319 S L + ++ N + +Q+ SLQN+ Q ++L ++E+ + Sbjct: 3301 NKQYLTSTSITLANDSNLFDRQANNDL--QKQIESLQNQNQMLTQNLTRMREEIDQRNTE 3358 Query: 1320 IEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKK 1379 I ++ E + ++ L+ ENQ + L ++E K Sbjct: 3359 IIEIKRERTETQINDNSQLKENLLNKEKEILRLKNENQELIKEITDKTLRLSEVEKNFLK 3418 Query: 1380 SSXXXXXXXXXXXXRVNDAEAKVLELTHQLELK--DSEIYQKTHEYTITLTQRNDEFENV 1437 + ++ + EA+ L +L D+E K + I Q+ N+ Sbjct: 3419 QTISSKDYEMSMKPKLLELEAENKSLKEELNANEVDNEKILKLKDDEINNLQKAKGDLNL 3478 Query: 1438 RQQLVEYEKRIEDLTYEKESELAILRLKMHEN--ANHYETMQKESEIERVKLIEELNVKI 1495 + +E ++I + KE L + ++++ N + KE+E +L I Sbjct: 3479 KIVAMENSQKINEKKKVKEIILKLQKMEVENKDLTNRLNDLMKENE--------DLKRNI 3530 Query: 1496 TESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQ 1555 ++ + ELNK L+E + T LE + ++ L + S I+ Sbjct: 3531 SDLMKGKSLTEELNKKLDEIKRSNIAISTELEITKQKLNKEESSKRKLMKKIEEQKSLIK 3590 Query: 1556 KHVSFASDTKQGRDEQLDNTMNKE 1579 K K+ ++++ E Sbjct: 3591 KLNEENDSLKKSEEDKIGKIKENE 3614 Score = 140 bits (340), Expect = 2e-31 Identities = 209/1065 (19%), Positives = 474/1065 (44%), Gaps = 101/1065 (9%) Query: 569 QKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISL---LESQKFD 625 Q+ EL +E NL+ ++ + + + IES + K+ E +N +T+ + + E+ K + Sbjct: 199 QEAEELTQENDNLRENIENLN--KEIES-LQNKIKENQNTPQTQQQYEEMKKKYENLKIE 255 Query: 626 LVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENL 685 + ++ Q+ DE+ +I +LQ + + ++ + + I S K I NL Sbjct: 256 NNSQKILIDQRTDELTKARQEIGKLQQELMGDDLPNDKAFKDIYKESQEK------IVNL 309 Query: 686 KLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQS 745 + + QL +++ + ++E++ KL N + N++ L K ++I++L ++ Q Sbjct: 310 QTENNQLKKDLENAKTEQENLNQKLNN-LNNNLNDNSLLNKSLNDQINQLKVEL----QK 364 Query: 746 KIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQ---- 801 T + D +QE+D IE ++ L+ K+ LEE+ +++ + K+D Sbjct: 365 MQNTIYKKDGDLQEKDDEIEQLKQTLNAQKTFSNELEETNKKLKEM-LNQNSKSDLTNSS 423 Query: 802 -LGSYLQEKQKAYSEYTIQEDE-LVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILL 859 L S+ KQ+ T QE+E L N+L L ++QLL ++ EN+ L++K Sbjct: 424 FLSSFNLTKQRLND--TKQENEQLQNQLMQL-------QQQLLILKQENENLKEKQNSYS 474 Query: 860 EENQN------LQISLSDMQQHYNALVEK-ANRTDLAESESTKYQTQLRDLESNLKRITH 912 + N L IS SD Q A++++ R ++ + ++ E++ K Sbjct: 475 DSLNNSSNMSALDISGSDFVQIDQAIIDQYEQRIKSLTDNISELREKISQKENSEKSNDS 534 Query: 913 EHQTLIVQKKKEI-----EDLEI-EFNTQIESAIRDKK--------VLNEKYEKNIEYV- 957 + ++Q KK + E+ I E N ++ + + K +LN+ K I+ + Sbjct: 535 QRSLELIQLKKSLDKAKKENYSIKEENFKLNQLLNNYKRKIDNLNQLLNDLNPKEIKLLL 594 Query: 958 TQLEAQ-----------LQEYKNNIEN-LNMNVEELNKMNLELIDKHVQKQQTQSPDYT- 1004 + L+ +++ KN + N L+ N + + + EL++ + Q +++ + Sbjct: 595 SSLKKDFLLKRDDFIKYIRKAKNEVRNALSENSDLIENLQNELLNMKEKLQNSKAENKQI 654 Query: 1005 ---EQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENME 1061 + IN++NK+ +++++E + N++ NN + S + T+ + ++ Sbjct: 655 LSLQPKINDLNKIMTQIQKENERLQKTNKEKNNEIEKLKDENENLVSNNKKLQTENKELK 714 Query: 1062 EEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPM 1121 E +++ + Q D N +L + E +QIK L + K + K +S+ ++ + Sbjct: 715 ENLEKETSQNSDLLNENSDLNDKLNELRNQIKTLNDDKTKQNQLLQKN----LSNQLKDL 770 Query: 1122 SDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETL 1181 D+ N++ L+ ++ Q S +E +K+N + E +L +L Sbjct: 771 LDENNSLKDQLAQLQSSNNQLQKDIKDLTRQNESKTKELQSKINEKENENQNLTEKLNSL 830 Query: 1182 NTELTGHDVVNQEQINQLKSKLEQLN-TENDNLLSTVAELRSSISSAVDQRGFEIAELWK 1240 +++ N++ N ++S LN ++N+N EL+ ++ +I + Sbjct: 831 QSQIQILQNGNEDLQNDIESITNALNQSQNEN-----KELKEENQKI--EKSNQILQYEN 883 Query: 1241 QHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQ 1300 + + +++ Q +L+ Q S ++K ++L + + S +E++N Q Q L+ Sbjct: 884 KEVKEQKEKLQNQIDDLKNQNSNLQNKVDELNEEISSINEEKSN------QEKEYQEMLK 937 Query: 1301 DKEEHLRNLQEKYADVINQI-EILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSY 1359 D E L+NL+ + + +I EIL + + + +N+ Sbjct: 938 DLETKLKNLEAERLESNKEITEILELDTTFDDSTISDHLRKQCEQLKSLIEQNKNQNEEI 997 Query: 1360 KQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQK 1419 + ++ Q+ ++ +N ++KK D + ++ +L ++E SEI Sbjct: 998 QNLKSQN-EDLTVKNEEMKKELMNNQTTICDLIKTSEDKDKEIDDLKQKIEKLKSEIDNS 1056 Query: 1420 THEYTITLTQ-RNDEFENVRQQLV---EYEKRIEDLTYEKESELAILRLKMHENANHYET 1475 + TLT+ + F+ ++ Q+ + +K++E + E +++K+ N ++ Sbjct: 1057 KKQLDTTLTEFKVSNFDELQSQISRNNDDKKKLEQKVQNLQKENEEMKIKLENKENERKS 1116 Query: 1476 MQKESEIERVKLIEELNVKITESVSLNK-QVAELNKALEEEVAKTNEMQTALENQEIEIV 1534 + S +E ++ L K+ + L++ Q+ EL K ++ +++ +++ E + Sbjct: 1117 L---SSLESENIL--LKQKLQNNDKLHQIQIGELQKEIDVLNQTKSKLSKEVDDITNENI 1171 Query: 1535 TLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKE 1579 TL ++I +M +++++K ++ QL+ ++ KE Sbjct: 1172 TLKNQINTTFSMSIDENNELKKKLNQLIKENNSYQLQLNQSVPKE 1216 >UniRef50_A2EN31 Cluster: Viral A-type inclusion protein, putative; n=1; Trichomonas vaginalis G3|Rep: Viral A-type inclusion protein, putative - Trichomonas vaginalis G3 Length = 5296 Score = 196 bits (479), Expect = 3e-48 Identities = 274/1470 (18%), Positives = 610/1470 (41%), Gaps = 75/1470 (5%) Query: 149 NTIKEKDNALSVLQVKMKIMETTILDLQEKI-NEKDQIIEAKNKATTXXXXXXXXXXXXX 207 ++ ++ N L + K++I T + D + + NEK Q+ + N Sbjct: 3360 DSANDEKNKLEQDKHKLEIDNTKLNDAKSHLENEKSQLAQQINDLNNKLQKLEEEKNKL- 3418 Query: 208 XXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEI 267 E+ K Q K EN + + Q LLK +E ++ E+ LE + EI Sbjct: 3419 ----EEEKAQNEKKLENSQQDGDKLGQQNQDLLKQLEEIKQKLQQTEQEKSALEQQKNEI 3474 Query: 268 SLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKK 327 + +++ Q+++ KQ ++ +EK+E ++K E+ K Sbjct: 3475 QNKLNEIEQQMKDSEKEKEDI--------KQKLQQVEQEKSETQKKLEEAEQQKNEIQNK 3526 Query: 328 IELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWS 387 +E E + E E +L K +++ + + ++ K + Sbjct: 3527 LEQTEQEKKNLENEKAETEKRLQETEEAKKNLANEKSEAERKLEEVQNEKAETERKLNEA 3586 Query: 388 QLSSETLNQD---TDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXG 444 + +++ L + T KK+ + E K E + L + K+ + +EK Sbjct: 3587 EEANKNLENEKNETQKKLEEAEQQKAETQ-KLLEQTEEAKKNLANEKSEAERKLQETEEA 3645 Query: 445 KDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEK 504 K L A + E ++ +E T + +NE + + L+ E N+ K +E+ Sbjct: 3646 KKNL-ANEKSEAERKLEEVQNEKAETERK-LNEAEEANKNLENEKNETQKK------LEE 3697 Query: 505 LKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFS-KVSDSNKEIVRLTEE 563 + + + +L ++ + A KN+ KS + KL++ ++ N + + S++ +++ + E Sbjct: 3698 AEQQKAETQKLLEQTEEAKKNLANEKSEAERKLQETEEAKKNLANEKSEAERKLEEVQNE 3757 Query: 564 LHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQK 623 +K+ E EE NL+ ++ + +E +K E + L E +A LE++K Sbjct: 3758 KAETERKLNEAEEANKNLENE--KNETQKKLEEAEQQKA-ETQKLLEQTEEAKKNLENEK 3814 Query: 624 FDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIE 683 + ++L ++ +E + +DI + + ++ + + + L +E +E Sbjct: 3815 SETEKKLQETEEAKKNLEQEKSDIQKKLDETKQQKVNLENEKAETQKLLEETEEAKKNLE 3874 Query: 684 NLKLDKEQ-LYGTI---KDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKI 739 N K + E+ L T K+L N+K + KL+ E + KL + AE+ ++ L Sbjct: 3875 NEKAETEKRLQETEEAKKNLANEKSEAERKLEEVQNEKAETERKLNE--AEEANKNLENE 3932 Query: 740 NHEEQSKI----QTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSL 795 +E Q K+ Q + +++ + +N+E+E S+ + ++ EE+ +E + + Sbjct: 3933 KNETQKKLEEAEQQKAETQKLLEQTEEAKKNLENEKSETEKKLQETEEAKKNLEQEKSDI 3992 Query: 796 ERKADQLGSYLQ--EKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQK 853 ++K D+ E +KA ++ ++E E + L + +K+L E E K L++ Sbjct: 3993 QKKLDETKQQKVNLENEKAETQKLLEETEEAKKN--LENEKAETQKKLDEAEEAKKNLEQ 4050 Query: 854 KN---QILLEENQNLQISLSDMQQHYNALVEKANRT-DLAESESTKYQTQLRDLESNLKR 909 + + LEE QN + +L + + +E+A + D E + + QL + + + Sbjct: 4051 EKSDAEKKLEEVQNEKSALENEKNETQKKLEEAEKAKDQIVEEKSAVERQLVESQKDSSE 4110 Query: 910 ITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKN 969 + + ++++ DL+ + N +E + DK+ NEK ++ + L+ QL + + Sbjct: 4111 NQKQQDEEKSKLQQQLSDLQNKLN-DLEKKLADKE--NEKEQEKTQK-DDLQKQLDQLQK 4166 Query: 970 NIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYT-EQYINEINKLNALLKQKDEEIIAL 1028 + +NL ++L N + + K T + ++N+ N N L+ ++ ++ Sbjct: 4167 DFDNLEREKQKLQDKNDSMKETIDSKNMLLDSFGTIKDHLNDANNNNKKLQDENNKLRDD 4226 Query: 1029 NQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQ 1088 QK + S++ D KLA + + EE+++ +L ++ + + +RE Sbjct: 4227 AQKATSKNNELQSIIDDLNRKLANLDAEKKATEEKLKNTEDKLKQAEAEKKATEDKLRET 4286 Query: 1089 DDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEE 1148 ++ KE +E E + E + ++ + V+ E+ Sbjct: 4287 ENAKKETEEKLAKTEEEKKQVEDKLAATEAAKKETEDKLKQTEDEKKATEDKLANVEAEK 4346 Query: 1149 EFIQERSVLQEQSAKLNTELQ---ECYTKIIQLETLNTELTGHDVVNQ-EQINQLKSKLE 1204 I++ E K E + E K + + TE + ++ +Q K+ +E Sbjct: 4347 SDIEQAKKETEDKLKQTEEEKAAVEAEKKATEDKLHETEEAKKETEDKLKQTEDEKAAVE 4406 Query: 1205 QLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAF 1264 Q E ++ L E + + + +++ E EL ++ + R + +K +L LS Sbjct: 4407 QAKKETEDKLKQTEEEKKATENKLEESEAEKKELGERFESSRGST-EKQVSDLENLLSKL 4465 Query: 1265 ESKYEQLLDS---VQSST-QEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQ- 1319 + + + + + ++S Q E K T +++ + + E+ + ++K A+V N+ Sbjct: 4466 KDELKNIKEDKSQLESKLKQAEAEKKATEDKLAKTEVEKAALEQAKKETEDKLANVENEK 4525 Query: 1320 --IEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQ-EQSILNINEENAQ 1376 E ++++ EK + + + ++ E+ NA+ Sbjct: 4526 KATETQKNDLAKEKTDLQKALAKLLKRQEQLDAEKKALEEKANALESEKKATEEKLANAE 4585 Query: 1377 LKKSSXXXXXXXXXXXXRVNDAEAKVLE-LTHQLELKDSEIYQKTHEYTITLTQRNDEFE 1435 +K +++E K E Q E + ++I E L +E + Sbjct: 4586 KEKKETQDKLKQTEDNLAKSESEKKATEDKLKQTESEKAQIEAAKKETEDKLQNAENEKK 4645 Query: 1436 NVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKI 1495 ++L + E++ + T EK E + E + E +++ K + +L+ +I Sbjct: 4646 AAEEKLKQSEEQ-KKATEEKLQEAEAEKKAEQEKLANIEAEKQQLGNASEKQVSDLSGEI 4704 Query: 1496 TESVSLNKQVAELNKALEEEVAKTNEMQTALENQ----EIEIVTLNDEITNLQNMVRASS 1551 ++ L KQ+AE K +EE+AK+ + + +N + ++ L ++ +L+ + S Sbjct: 4705 SKLKQLLKQLAEAKKKADEELAKSKQDKEQSDNDKSKLQEDLNNLKKQLEDLEKAKKESD 4764 Query: 1552 SK---IQKHVSFASDTKQGRDEQLDNTMNK 1578 S + V+ + + +D+++ N +K Sbjct: 4765 SNNKLLADSVNKLKEQNKQKDDEIKNLTDK 4794 Score = 188 bits (457), Expect = 1e-45 Identities = 266/1383 (19%), Positives = 594/1383 (42%), Gaps = 108/1383 (7%) Query: 233 KDEKQRLLKDIES--KDVRISSLE-EANKLLEAARFEISLEHSKLAQELEQXXXXXXXXX 289 K E QRL ++E + +SS + E K +E E+ + + L+ E +Q Sbjct: 2957 KLENQRLNSELEKLKSNQPVSSNDPELQKQIE----ELKKQLNNLSNEKKQIETEKNGLQ 3012 Query: 290 XXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKL 349 L Q+ E E K +++E+ A M E+ ++ L Q+ +TN LENK+ Sbjct: 3013 GQIGRLESQN-ESLIESKKDMKEQNDKLQAQMDEMRRENNSLRQNQTQLERTNNGLENKV 3071 Query: 350 ATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAK 409 + + V + + K N K+++ +L++E + + K EI K Sbjct: 3072 GNLTDQLNQVKNQLSALQDQLKSKENEN--EKLRNEREKLANEKNSVELQSKDKDAEIIK 3129 Query: 410 LEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVG 469 L+ + LN DK ++++ D L Q++ QQ +L + Sbjct: 3130 LKSDAEHLN----DKINSLNDEKNKLQQA------NDKLNDQIEQMKQQIN---NLTNEN 3176 Query: 470 TNTEDVNEIAKVQEQLKQELNDEIKDVNV-KDLIEKLKSAEE-QITQLNDEIDAANKNMI 527 N E E AK QE++ Q + ++K + K +E S E +I +L D I + + Sbjct: 3177 KNMEQ--EKAKNQEKI-QNIEPKLKQLEEEKSKLEDENSQNENEIQRLKDTIKELSDKLA 3233 Query: 528 KVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVD 587 K + ++KL + T D +V D + + +L ++L +L+ + +L+++K L Sbjct: 3234 KSEEDNKLLKQSSSGTTDK--QVEDLQEMLNKLRDDLKNLNSENEQLKQQKDQL------ 3285 Query: 588 YDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADI 647 S ++ S+ K E +N E K + L ++K + + Q +VE + Sbjct: 3286 --SEKLNNSNNDKTKAETQN--EQLSKQLEQLNNEKNQMFNKYKNAIQDKAKVEIAKETL 3341 Query: 648 SQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIM 707 ++ ++++ SE +S L++++D+ + K +L L++D +L LEN+K + Sbjct: 3342 AK-DNEKLASEKES--LQQKLDSANDEKNKLEQDKHKLEIDNTKLNDAKSHLENEKSQLA 3398 Query: 708 NKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENI 767 ++ DL +KL+K+ EK K +E++ + Q G Q +DL Sbjct: 3399 QQIN-------DLNNKLQKLEEEKNKLEEEKAQNEKKLENSQQDGDKLGQQNQDLL---- 3447 Query: 768 ESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRL 827 +L + K ++ + E+ + +E ++ ++ K +++ +++ +K +++++ +L Sbjct: 3448 -KQLEEIKQKLQQTEQEKSALEQQKNEIQNKLNEIEQQMKDSEK-------EKEDIKQKL 3499 Query: 828 AVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSD----MQQHYNALVEKA 883 + +K+L E E + E+Q K + +E +NL+ ++ +Q+ A A Sbjct: 3500 QQVEQEKSETQKKLEEAEQQKNEIQNKLEQTEQEKKNLENEKAETEKRLQETEEAKKNLA 3559 Query: 884 NRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDK 943 N AE + + Q + + E L ++ L +K + + LE + E+ + Sbjct: 3560 NEKSEAERKLEEVQNEKAETERKLNEAEEANKNLENEKNETQKKLEEAEQQKAET----Q 3615 Query: 944 KVL--NEKYEKNI-EYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDK--HVQKQQT 998 K+L E+ +KN+ ++ E +LQE + +NL E + E+ ++ +++ Sbjct: 3616 KLLEQTEEAKKNLANEKSEAERKLQETEEAKKNLANEKSEAERKLEEVQNEKAETERKLN 3675 Query: 999 QSPDYTEQYINEINKLNALLKQKDE---EIIALNQKINNAQVSYMSMVSDYESKLAQFTT 1055 ++ + + NE N+ L++ ++ E L ++ A+ + + S+ E KL + Sbjct: 3676 EAEEANKNLENEKNETQKKLEEAEQQKAETQKLLEQTEEAKKNLANEKSEAERKLQETEE 3735 Query: 1056 KLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIIS 1115 +N+ E ++L + + E + + E ++ K L+ K + + + E Sbjct: 3736 AKKNLANEKSEAERKLEEVQNEKAETERKLNEAEEANKNLENEKNETQKKLEEAEQQKAE 3795 Query: 1116 S--TIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYT 1173 + +E + N++ K+QE EE + L+++ + + +L E Sbjct: 3796 TQKLLEQTEEAKKNLENEKSETEK-----KLQETEE---AKKNLEQEKSDIQKKLDETKQ 3847 Query: 1174 KIIQLETLNTE---LTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQ 1230 + + LE E L ++ + K++ E+ E + +A +S +++ Sbjct: 3848 QKVNLENEKAETQKLLEETEEAKKNLENEKAETEKRLQETEEAKKNLANEKSEAERKLEE 3907 Query: 1231 RGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTME 1290 E AE ++ L + E + E+E E +Q ++ + Q E K Sbjct: 3908 VQNEKAET-ERKLNEAEEANKNLENEKNETQKKLEEAEQQKAETQKLLEQTEEAKKNLEN 3966 Query: 1291 QVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSE---IEDEKVAFXXXXXXXXXXXXX 1347 + + + KLQ+ EE +NL+++ +D+ +++ + + +E+EK A Sbjct: 3967 EKSETEKKLQETEEAKKNLEQEKSDIQKKLDETKQQKVNLENEK-AETQKLLEETEEAKK 4025 Query: 1348 XXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLE--- 1404 + + E Q E++ N+ +E + +K N+ + K+ E Sbjct: 4026 NLENEKAETQKKLDEAEEAKKNLEQEKSDAEKKLEEVQNEKSALENEKNETQKKLEEAEK 4085 Query: 1405 ----LTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDL---TYEKES 1457 + + + ++ + + + Q+++E ++QQL + + ++ DL +KE+ Sbjct: 4086 AKDQIVEEKSAVERQLVESQKDSSENQKQQDEEKSKLQQQLSDLQNKLNDLEKKLADKEN 4145 Query: 1458 ELAILRLKMHENANHYETMQKE-SEIERVK-LIEELNVKITESVSLNKQVAELNKALEEE 1515 E + + + + +QK+ +ER K +++ N + E++ + + +++ Sbjct: 4146 EKEQEKTQKDDLQKQLDQLQKDFDNLEREKQKLQDKNDSMKETIDSKNMLLDSFGTIKDH 4205 Query: 1516 VAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNT 1575 + N L+++ ++ + T+ N +++ + + ++ K+ +E+L NT Sbjct: 4206 LNDANNNNKKLQDENNKLRDDAQKATSKNNELQSIIDDLNRKLANLDAEKKATEEKLKNT 4265 Query: 1576 MNK 1578 +K Sbjct: 4266 EDK 4268 Score = 176 bits (428), Expect = 5e-42 Identities = 287/1465 (19%), Positives = 609/1465 (41%), Gaps = 99/1465 (6%) Query: 149 NTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXX 208 N KEK ++ K ++ TI L+ +++ + + +K + Sbjct: 2608 NYEKEKAEREKEVEENNKKLKDTINALENRLDSQGEQTRSKINSAEQTARKAKEDADSAV 2667 Query: 209 XXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLL------EA 262 + + ++ +++ + +E + K EK+ + E++ ++ + E+A ++ E Sbjct: 2668 IAQKSLQAELNNLKQKYAVLEDQLKTEKENHQQ--EAQQLKELAEEDATPMVCIHVVGEK 2725 Query: 263 ARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMT 322 + ++ ++ KL++ + L KQ + + E + G+L+ T Sbjct: 2726 LK-KLQNDNEKLSENNDNLQKNINELKDKINGLEKQYKQDAAELSNVHHQLGALQ-EKAT 2783 Query: 323 ELTKKIELLEHLNCQIRQTNKELEN-KLATMGTESKAVSSPSKKGSPLISRKSGRNTASK 381 L + + L+ N + NK+LE K + S + + + L++RK + K Sbjct: 2784 NLENENKSLKEENEDLMNQNKQLEKEKQQLLAQNSNLEENKNNQEQSLMNRKKKNDDLLK 2843 Query: 382 MKSPWSQLSSETLNQDTDKKINK--NEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXX 439 +L E L ++ + K N ++EM+ +N D KE + S +D Sbjct: 2844 QIDDL-KLELEELKRNNSQNETKLQNANQQIEMMKDQINND---KEQIKSAQDKLNDLQN 2899 Query: 440 XXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVK 499 + Q+ LE+Q+ M + ++ + +N+ E K+ D+I D+ + Sbjct: 2900 K---NNELNSNQIVLENQKKMYEGLYNDMKSSNDKLND-----ENRKK--TDQIIDLTKQ 2949 Query: 500 DLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVR 559 + E Q +LN E++ N V SN KQ+++ + +S+ K+I Sbjct: 2950 NAEVSALKLENQ--RLNSELEKLKSNQ-PVSSNDPELQKQIEELKKQLNNLSNEKKQI-- 3004 Query: 560 LTEELHHLSQKVAELEEEKGNLQLHLVDY-DSGRMIESDVYKKMIEMENLAE--TRLKAI 616 E + L ++ LE + +L D + +++ + + E +L + T+L+ Sbjct: 3005 -ETEKNGLQGQIGRLESQNESLIESKKDMKEQNDKLQAQMDEMRRENNSLRQNQTQLERT 3063 Query: 617 SL-LESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASK 675 + LE++ +L +L+ ++ + ++D+L + +++++ +E + + E+ L + Sbjct: 3064 NNGLENKVGNLTDQLNQVKNQLSALQDQLKS-KENENEKLRNEREKLANEKNSVELQSKD 3122 Query: 676 KELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISEL 735 K+ ++ LK D E L I L ++K NKLQ Q N L D++E+M ++I+ L Sbjct: 3123 KDAEII--KLKSDAEHLNDKINSLNDEK----NKLQ---QANDKLNDQIEQMK-QQINNL 3172 Query: 736 LAKINHEEQSKIQTQF---GIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRR 792 + + EQ K + Q I+ K+++ + +E E S+ ++ I RL+++I + D+ Sbjct: 3173 TNENKNMEQEKAKNQEKIQNIEPKLKQLEEEKSKLEDENSQNENEIQRLKDTIKELSDKL 3232 Query: 793 YSLERKADQLGSYLQEKQKAYSEYTIQE-DELVNRLAVLMDHDRVVEKQLLEIEHENKEL 851 K+++ L++ ++ +++ E++N+L + + +QL + + + E Sbjct: 3233 ----AKSEEDNKLLKQSSSGTTDKQVEDLQEMLNKLRDDLKNLNSENEQLKQQKDQLSEK 3288 Query: 852 --QKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKR 909 N E QN Q+S ++Q N + N+ A + K + L + ++ Sbjct: 3289 LNNSNNDKTKAETQNEQLS-KQLEQLNNEKNQMFNKYKNAIQDKAKVEIAKETLAKDNEK 3347 Query: 910 ITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKN 969 + E ++L QK D + + D LN+ +QL Q+ + N Sbjct: 3348 LASEKESL-QQKLDSANDEKNKLEQDKHKLEIDNTKLNDAKSHLENEKSQLAQQINDLNN 3406 Query: 970 NIENLNMNVEELNKMNLELI--DKHVQKQQTQSPDYTEQ---YINEINKLNALLKQKDEE 1024 ++ L EE NK+ E +K ++ Q +Q + ++ ++ L+Q ++E Sbjct: 3407 KLQKLE---EEKNKLEEEKAQNEKKLENSQQDGDKLGQQNQDLLKQLEEIKQKLQQTEQE 3463 Query: 1025 IIALNQKINNAQVSYMSM---VSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEEL 1081 AL Q+ N Q + + D E + KL+ +E+E K+L +++Q E+ Sbjct: 3464 KSALEQQKNEIQNKLNEIEQQMKDSEKEKEDIKQKLQQVEQEKSETQKKLEEAEQQKNEI 3523 Query: 1082 QILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXX 1141 Q + + + + K L+ K E + +TE + E S+ ++ Sbjct: 3524 QNKLEQTEQEKKNLENEKAETEKRLQETEEAKKNLANEK-SEAERKLEEVQNEKAETERK 3582 Query: 1142 LKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKS 1201 L EE E + Q E Q+ T+ + LE TE ++ N++ ++ + Sbjct: 3583 LNEAEEANKNLENEKNETQKKLEEAEQQKAETQKL-LE--QTEEAKKNLANEK--SEAER 3637 Query: 1202 KLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQL 1261 KL++ NL + +E + +++ +L + A + + +K E + +++ Sbjct: 3638 KLQETEEAKKNLANEKSEAERKLEEVQNEKAETERKLNEAEEANKNLENEKNETQKKLEE 3697 Query: 1262 SAFE-SKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQI 1320 + + ++ ++LL+ EE K + E+ + + KLQ+ EE +NL + ++ ++ Sbjct: 3698 AEQQKAETQKLLEQT-----EEAKKNLANEK-SEAERKLQETEEAKKNLANEKSEAERKL 3751 Query: 1321 EILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKS 1380 E E+++EK A + + E Q + EQ + Q +++ Sbjct: 3752 E----EVQNEK-AETERKLNEAEEANKNLENEKNETQKKLEEAEQQKAETQKLLEQTEEA 3806 Query: 1381 SXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQK---THEYTITLTQRNDEFENV 1437 ++ + E E LE + S+I +K T + + L E + + Sbjct: 3807 KKNLENEKSETEKKLQETE----EAKKNLEQEKSDIQKKLDETKQQKVNLENEKAETQKL 3862 Query: 1438 RQQLVEYEKRIEDLTYEKESELAILRLKMHENANHY-ETMQKESEIERVKLIEELNVKIT 1496 ++ E +K +E+ E E L AN E +K E++ K E + Sbjct: 3863 LEETEEAKKNLENEKAETEKRLQETEEAKKNLANEKSEAERKLEEVQNEKAETERKLNEA 3922 Query: 1497 ESVSLN--KQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKI 1554 E + N + E K LEE + E Q LE E L +E + + ++ + Sbjct: 3923 EEANKNLENEKNETQKKLEEAEQQKAETQKLLEQTEEAKKNLENEKSETEKKLQETEEAK 3982 Query: 1555 QKHVSFASDTKQGRDEQLDNTMNKE 1579 + SD ++ DE +N E Sbjct: 3983 KNLEQEKSDIQKKLDETKQQKVNLE 4007 Score = 173 bits (421), Expect = 3e-41 Identities = 328/1571 (20%), Positives = 654/1571 (41%), Gaps = 160/1571 (10%) Query: 143 DVTHLSNTIKE-KDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXX 201 +V +N +KE DN + LQ + I DLQ+K++++++ IE KA Sbjct: 1935 NVDEENNEMKEGADNLIDALQQSVDEKNKQIDDLQQKLDDQNREIELL-KAKV-----EQ 1988 Query: 202 XXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLE 261 ED T+ E E ++ K+RL + I +++ ++ + ++ Sbjct: 1989 IENINEEEDNEDIVVASTRDVELENVEEESPEEAKERLAEQISQLQDKLTEKKKNSLQMK 2048 Query: 262 AARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANM 321 A E SKL +E+EQ L + E + E+ ++K S E N Sbjct: 2049 QALASKDAEISKLNEEIEQIKSEKEDQDKELEKLNNELTE-ALEKLENGKKKSSQEQNNE 2107 Query: 322 TE--LTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPL-ISRKSGRNT 378 E IE L+ ++ N+ L+N+ K++ + K L S + N Sbjct: 2108 NEEDFVDDIEKLKEERENLKSENESLKNQAPENEGLKKSLENLKKSNDDLNKSNEDKENK 2167 Query: 379 ASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXX 438 +++S S+L SE + + K EI L + S+ +D ++D Sbjct: 2168 IKELESEISKLKSEINELEQNNKDKDREIEILSSKVSSIENVNLD-----DDEDDITVVG 2222 Query: 439 XXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQ--EQLKQELNDEIKDV 496 +T+ + E + E + + TN + ++ + + K + ++ K + Sbjct: 2223 TRDISVDETIPTDNETETKTEPETNTNTNENTNETNEENVSSQEGNNEEKNQSKEDKKKL 2282 Query: 497 NVKDLIEKLKSAEEQITQL---NDEIDAANKNMIKVKSNHKL--KLKQMQKTIDNFS--- 548 ++ L + L S + ++ L ND++ + N+ + KSNH+L K K++++ I+N + Sbjct: 2283 RIQQLKQLLASKQGEVDALKSQNDDLKSENETL--SKSNHELGTKTKELEEEIENINNNK 2340 Query: 549 --KVSD----SNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDS----GRMIESDV 598 +V D S+ E+V T ++ + + E K L+ L + ++ + E ++ Sbjct: 2341 EGEVIDEKEASDVEVVCSTRDVDFEYENENDPETLKSLLKSKLSELENLQKENKAKEDEI 2400 Query: 599 YKKMIEM--------ENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDK------- 643 K E+ LAET + + + + +L E + Q+ ++++ Sbjct: 2401 TKLNEELAKSEDAKRRELAETAERLNNEINTLHDELQNEQNARQKLIEDLQSNNKEPEKD 2460 Query: 644 ----LADISQLQSDQVCSEIKSV-HLE-EQIDALSASKKEL-ALVIENLKLDKEQLYGTI 696 ++ + +SD++ ++ + H + E+I AL + E +++L+ L + Sbjct: 2461 DNGDFMNVLEKKSDEINKALEEILHRQNEEIKALRDREAEKNKQTVDDLQKQIAMLNNKL 2520 Query: 697 KDLENDKEDIMNK---LQNYIQEN-MDLTDKLEKMSAEKISELLAKI------NHEEQSK 746 K + D + K Q E+ D + K +K +E++AK+ +EE K Sbjct: 2521 KPSDQTDNDQLQKELMFQEIEGESPEDRNKRYLKAIEDKFNEIIAKLQESINNQNEELKK 2580 Query: 747 IQTQF-GIDA---KIQERDLYIENIESELSKYKS-RICRLEESIAVMEDRRYSLERKADQ 801 ++ + G+DA ++ ++ + I+ K K+ R +EE+ ++D +LE + D Sbjct: 2581 LRQKCDGVDAIELQLAQKKAELNEIKDNYEKEKAEREKEVEENNKKLKDTINALENRLDS 2640 Query: 802 LGSYLQEK--------QKAYSE---YTIQEDELVNRLAVLMDHDRVVEKQL-LEIEHENK 849 G + K +KA + I + L L L V+E QL E E+ + Sbjct: 2641 QGEQTRSKINSAEQTARKAKEDADSAVIAQKSLQAELNNLKQKYAVLEDQLKTEKENHQQ 2700 Query: 850 ELQKKNQILLEENQNLQISL----SDMQQHYNALVEKANRTDLAESESTKYQTQLRDLES 905 E Q+ + L EE+ + + +++ N + + D + + + ++ LE Sbjct: 2701 EAQQLKE-LAEEDATPMVCIHVVGEKLKKLQNDNEKLSENNDNLQKNINELKDKINGLEK 2759 Query: 906 NLKRITHE-----HQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQL 960 K+ E HQ +Q+K +LE E N ++ D N++ EK + + Sbjct: 2760 QYKQDAAELSNVHHQLGALQEK--ATNLENE-NKSLKEENEDLMNQNKQLEKEKQQLLAQ 2816 Query: 961 EAQLQEYKNNIENLNMNVEELN----------KMNLELIDKHVQKQQTQSPDYTEQ---Y 1007 + L+E KNN E MN ++ N K+ LE + ++ + +T+ + +Q Sbjct: 2817 NSNLEENKNNQEQSLMNRKKKNDDLLKQIDDLKLELEELKRNNSQNETKLQNANQQIEMM 2876 Query: 1008 INEINKLNALLKQKDEEIIALNQK---INNAQVSYMSMVSDYESKLAQFTTKLENMEEEM 1064 ++IN +K +++ L K +N+ Q+ + YE + + + +E Sbjct: 2877 KDQINNDKEQIKSAQDKLNDLQNKNNELNSNQIVLENQKKMYEGLYNDMKSSNDKLNDEN 2936 Query: 1065 QRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLT--FEMNIPKTEGMI--ISSTIEP 1120 ++ + Q++D + N E+ L E EL++ K N P+ + I + + Sbjct: 2937 RKKTDQIIDLTKQNAEVSALKLENQRLNSELEKLKSNQPVSSNDPELQKQIEELKKQLNN 2996 Query: 1121 MSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLET 1180 +S++ ++ L+ Q E I+ + ++EQ+ KL ++ E + L Sbjct: 2997 LSNEKKQIETEKNGLQGQIGRLESQ-NESLIESKKDMKEQNDKLQAQMDEMRRENNSLRQ 3055 Query: 1181 LNTEL--TGHDVVNQ-----EQINQLKSKLEQL-------NTENDNLLSTVAELRSSISS 1226 T+L T + + N+ +Q+NQ+K++L L EN+ L + +L + +S Sbjct: 3056 NQTQLERTNNGLENKVGNLTDQLNQVKNQLSALQDQLKSKENENEKLRNEREKLANEKNS 3115 Query: 1227 AVDQRGFEIAELWK-----QHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQE 1281 Q + AE+ K +HL + +++L+ + EQ+ + + T E Sbjct: 3116 VELQSKDKDAEIIKLKSDAEHLNDKINSLNDEKNKLQQANDKLNDQIEQMKQQINNLTNE 3175 Query: 1282 ETN----KIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIED--EKVAFX 1335 N K E++ +++ KL+ EE L+++ + N+I+ L+ I++ +K+A Sbjct: 3176 NKNMEQEKAKNQEKIQNIEPKLKQLEEEKSKLEDENSQNENEIQRLKDTIKELSDKLAKS 3235 Query: 1336 XXXXXXXXXXXXXXXDLRTEN-QSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXR 1394 D + E+ Q + N+N EN QLK+ Sbjct: 3236 EEDNKLLKQSSSGTTDKQVEDLQEMLNKLRDDLKNLNSENEQLKQQKDQLSEKLNNSNND 3295 Query: 1395 VNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYE 1454 AE + +L+ QLE ++E Q ++Y + Q + E ++ L K E L E Sbjct: 3296 KTKAETQNEQLSKQLEQLNNEKNQMFNKYKNAI-QDKAKVEIAKETLA---KDNEKLASE 3351 Query: 1455 KESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELN---KA 1511 KES L ++ N E + + EI+ KL + + E L +Q+ +LN + Sbjct: 3352 KESLQQKLD-SANDEKNKLEQDKHKLEIDNTKLNDAKSHLENEKSQLAQQINDLNNKLQK 3410 Query: 1512 LEEEVAKTNE----MQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQG 1567 LEEE K E + LEN + + L + +L + K+Q+ S +Q Sbjct: 3411 LEEEKNKLEEEKAQNEKKLENSQQDGDKLGQQNQDLLKQLEEIKQKLQQTEQEKSALEQQ 3470 Query: 1568 RDEQLDNTMNK 1578 ++E + N +N+ Sbjct: 3471 KNE-IQNKLNE 3480 Score = 149 bits (361), Expect = 6e-34 Identities = 303/1552 (19%), Positives = 631/1552 (40%), Gaps = 148/1552 (9%) Query: 147 LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINE-KDQIIEAKNKATTXXXXXXXXXXX 205 + + KD +S L +++ +++ D +++ + +++ EA K Sbjct: 2047 MKQALASKDAEISKLNEEIEQIKSEKEDQDKELEKLNNELTEALEKLENGKKKSSQEQNN 2106 Query: 206 XXXXXXEDTKQQMTKMQENFIAMEAEWKD---EKQRLLKDIESKDVRISSLEEANKLLEA 262 D +++ + +EN + K+ E + L K +E+ L ++N+ E Sbjct: 2107 ENEEDFVDDIEKLKEERENLKSENESLKNQAPENEGLKKSLENLKKSNDDLNKSNEDKEN 2166 Query: 263 ARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQ--SIEPSC--EEKTEIEEKGSLEI 318 E+ E SKL E+ + L+ + SIE +++ +I G+ +I Sbjct: 2167 KIKELESEISKLKSEINELEQNNKDKDREIEILSSKVSSIENVNLDDDEDDITVVGTRDI 2226 Query: 319 A--------NMTELTKKIELLEHLNCQIRQTNKELENKLATMGT-ESKAVSSPSKKG--- 366 + N TE + E + N +TN+E N + G E K S KK Sbjct: 2227 SVDETIPTDNETETKTEPETNTNTNENTNETNEE--NVSSQEGNNEEKNQSKEDKKKLRI 2284 Query: 367 ---SPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVD 423 L++ K G A K ++ + +ETL++ + K + +LE I+++N + Sbjct: 2285 QQLKQLLASKQGEVDALKSQNDDLKSENETLSKSNHELGTKTK--ELEEEIENINNNKEG 2342 Query: 424 KEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQE 483 + VI EK+ D + + E+ L + E++ + K +E Sbjct: 2343 E--VIDEKEASDVEVVCSTRDVDF---EYENENDPETLKSLLKSKLSELENLQKENKAKE 2397 Query: 484 QLKQELNDEI---KDVNVKDLIEKLKSAEEQITQLNDEI----DAANKNMIKVKSNHKLK 536 +LN+E+ +D ++L E + +I L+DE+ +A K + ++SN+K Sbjct: 2398 DEITKLNEELAKSEDAKRRELAETAERLNNEINTLHDELQNEQNARQKLIEDLQSNNKEP 2457 Query: 537 LKQMQKTIDN-FSKVSDSNKEIVRLTEE-LHHLSQKVAELEEEKGNLQLHLVDYDSGRMI 594 K N K SD EI + EE LH ++++ L + + VD D + I Sbjct: 2458 EKDDNGDFMNVLEKKSD---EINKALEEILHRQNEEIKALRDREAEKNKQTVD-DLQKQI 2513 Query: 595 ESDVYKKMIEMENLAETRLKAISLLESQKFDLVQE-----LHILQQKYDEVEDKLADISQ 649 + K+ + +L+ + + + + ++ L ++ K++E+ KL + Sbjct: 2514 AM-LNNKLKPSDQTDNDQLQKELMFQEIEGESPEDRNKRYLKAIEDKFNEIIAKLQESIN 2572 Query: 650 LQSDQVCSEIKSVHLEEQIDALSASKK-ELALVIENLKLDKEQLYGTIKDLENDKEDIMN 708 Q++++ + + I+ A KK EL + +N + +K + +++ +D +N Sbjct: 2573 NQNEELKKLRQKCDGVDAIELQLAQKKAELNEIKDNYEKEKAEREKEVEENNKKLKDTIN 2632 Query: 709 KLQNYIQENMDLT-DKLE--KMSAEKISE-----------LLAKINH--------EEQSK 746 L+N + + T K+ + +A K E L A++N+ E+Q K Sbjct: 2633 ALENRLDSQGEQTRSKINSAEQTARKAKEDADSAVIAQKSLQAELNNLKQKYAVLEDQLK 2692 Query: 747 IQTQFGIDAKIQERDLYIENIESELSKYK--SRICRLEESIAVMEDRRYSLERKADQLGS 804 + + Q ++L E+ + + ++ +L+ + + +L++ ++L Sbjct: 2693 TEKENHQQEAQQLKELAEEDATPMVCIHVVGEKLKKLQNDNEKLSENNDNLQKNINELKD 2752 Query: 805 YLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQN 864 + +K Y + + + ++L L + +E + ++ EN++L +N+ L +E Q Sbjct: 2753 KINGLEKQYKQDAAELSNVHHQLGALQEKATNLENENKSLKEENEDLMNQNKQLEKEKQQ 2812 Query: 865 LQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKE 924 L S+++++ N + + K L+ LKR +++T + ++ Sbjct: 2813 LLAQNSNLEENKNNQEQSLMNRKKKNDDLLKQIDDLKLELEELKRNNSQNETKLQNANQQ 2872 Query: 925 IEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQ---LEAQLQEYKNNIENLNMNVEEL 981 IE ++ + N E + LN+ KN E + LE Q + Y+ ++ + ++L Sbjct: 2873 IEMMKDQINNDKEQIKSAQDKLNDLQNKNNELNSNQIVLENQKKMYEGLYNDMKSSNDKL 2932 Query: 982 NKMNL----ELIDKHVQKQQTQSPDYTEQYIN-EINKL--NALLKQKDEE----IIALNQ 1030 N N ++ID Q + + Q +N E+ KL N + D E I L + Sbjct: 2933 NDENRKKTDQIIDLTKQNAEVSALKLENQRLNSELEKLKSNQPVSSNDPELQKQIEELKK 2992 Query: 1031 KINN----------------AQVSYMSMVSD--YESK--LAQFTTKLENMEEEMQRVSKQ 1070 ++NN Q+ + ++ ESK + + KL+ +EM+R + Sbjct: 2993 QLNNLSNEKKQIETEKNGLQGQIGRLESQNESLIESKKDMKEQNDKLQAQMDEMRRENNS 3052 Query: 1071 LLDS----KQHNEELQILVREQDDQIKELKE--TKLTFEMNIPKTEGMIISSTIEPMSDD 1124 L + ++ N L+ V DQ+ ++K + L ++ + E + + E ++++ Sbjct: 3053 LRQNQTQLERTNNGLENKVGNLTDQLNQVKNQLSALQDQLKSKENENEKLRNEREKLANE 3112 Query: 1125 ANNVDXXXXXXXXXXXXLKVQEE------EEFIQERSVLQEQSAKLNTELQECYTKIIQL 1178 N+V+ LK E E++ LQ+ + KLN ++++ +I L Sbjct: 3113 KNSVELQSKDKDAEIIKLKSDAEHLNDKINSLNDEKNKLQQANDKLNDQIEQMKQQINNL 3172 Query: 1179 ETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNL-------LSTVAELRSSISSAVDQ- 1230 N + NQE+I ++ KL+QL E L + + L+ +I D+ Sbjct: 3173 TNENKNMEQEKAKNQEKIQNIEPKLKQLEEEKSKLEDENSQNENEIQRLKDTIKELSDKL 3232 Query: 1231 -RGFEIAELWKQHLA----QREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNK 1285 + E +L KQ + ++ D Q+ ++LR L S+ EQL +++ N Sbjct: 3233 AKSEEDNKLLKQSSSGTTDKQVEDLQEMLNKLRDDLKNLNSENEQLKQQKDQLSEKLNNS 3292 Query: 1286 IVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXX 1345 + + +L + E L N + + + ++++E K Sbjct: 3293 NNDKTKAETQNEQLSKQLEQLNNEKNQMFNKYKNAIQDKAKVEIAKETLAKDNEKLASEK 3352 Query: 1346 XXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLEL 1405 L + N K EQ + +N +L + ++ND K+ +L Sbjct: 3353 ESLQQKLDSANDE-KNKLEQDKHKLEIDNTKLNDAKSHLENEKSQLAQQINDLNNKLQKL 3411 Query: 1406 THQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLK 1465 + + E Q + Q D+ Q L++ + I+ + E E + L + Sbjct: 3412 EEEKNKLEEEKAQNEKKLE-NSQQDGDKLGQQNQDLLKQLEEIKQKLQQTEQEKSALEQQ 3470 Query: 1466 MHE---NANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEM 1522 +E N E K+SE E+ E++ K+ + + ++ +E K LEE + NE+ Sbjct: 3471 KNEIQNKLNEIEQQMKDSEKEK----EDIKQKLQQ---VEQEKSETQKKLEEAEQQKNEI 3523 Query: 1523 QTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDN 1574 Q LE E E L +E + ++ + + +K+++ + + E++ N Sbjct: 3524 QNKLEQTEQEKKNLENEKAETEKRLQ-ETEEAKKNLANEKSEAERKLEEVQN 3574 Score = 135 bits (327), Expect = 8e-30 Identities = 260/1383 (18%), Positives = 584/1383 (42%), Gaps = 135/1383 (9%) Query: 244 ESKDVRISSLEEANKLLEAARFEIS-LEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEP 302 ES+D + S EE + +E + ++ L++S + +++ +QS++ Sbjct: 1903 ESEDNK--SPEELKREIENLKKQLEDLKNSGSQENVDEENNEMKEGADNLIDALQQSVDE 1960 Query: 303 SCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSP 362 ++ ++++K + + ++IELL+ QI N+E +N E V+S Sbjct: 1961 KNKQIDDLQQK-------LDDQNREIELLKAKVEQIENINEEEDN-------EDIVVAST 2006 Query: 363 SKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLV 422 + +S ++ SQL + + + K +A + I LN+++ Sbjct: 2007 RDVELENVEEESPEEAKERLAEQISQLQDKLTEKKKNSLQMKQALASKDAEISKLNEEI- 2065 Query: 423 DKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQ 482 E + SEK+ + +L+ ++ + + + +D+ ++ + + Sbjct: 2066 --EQIKSEKEDQDKELEKLNNELTEALEKLENGKKKSSQEQNNENEEDFVDDIEKLKEER 2123 Query: 483 EQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQK 542 E LK E N+ +K+ ++ E LK + E + + ND+++ +N++ K N K+K+++ Sbjct: 2124 ENLKSE-NESLKNQAPEN--EGLKKSLENLKKSNDDLNKSNED----KEN---KIKELES 2173 Query: 543 TIDNF-SKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDV-YK 600 I S++++ + E+ LS KV+ +E N+ L + D + D+ Sbjct: 2174 EISKLKSEINELEQNNKDKDREIEILSSKVSSIE----NVNLDDDEDDITVVGTRDISVD 2229 Query: 601 KMIEMENLAETRLK-AISLLESQKFDLVQELHILQQK--YDEVEDKLADISQLQSDQVCS 657 + I +N ET+ + + ++ + E ++ Q+ +E D +L+ Q+ Sbjct: 2230 ETIPTDNETETKTEPETNTNTNENTNETNEENVSSQEGNNEEKNQSKEDKKKLRIQQLKQ 2289 Query: 658 EIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQEN 717 + S + ++DAL + +L E L +L K+LE + E+I N + + + Sbjct: 2290 LLAS--KQGEVDALKSQNDDLKSENETLSKSNHELGTKTKELEEEIENINNNKEGEVIDE 2347 Query: 718 MDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSR 777 + +D S + +E ++ +T + + ++ + +EN++ E + Sbjct: 2348 KEASDVEVVCSTRDVD-----FEYENENDPET---LKSLLKSKLSELENLQKENKAKEDE 2399 Query: 778 ICRLEESIAVMED-RRYSLERKADQLGS-------YLQEKQKAYSEY---------TIQE 820 I +L E +A ED +R L A++L + LQ +Q A + ++ Sbjct: 2400 ITKLNEELAKSEDAKRRELAETAERLNNEINTLHDELQNEQNARQKLIEDLQSNNKEPEK 2459 Query: 821 DELVNRLAVLMDHDRVVEKQLLEIEH-ENKELQKKNQILLEENQNLQISLSDMQQHYNAL 879 D+ + + VL + K L EI H +N+E++ E+N+ ++ D+Q+ L Sbjct: 2460 DDNGDFMNVLEKKSDEINKALEEILHRQNEEIKALRDREAEKNKQ---TVDDLQKQIAML 2516 Query: 880 VEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESA 939 K +D +++ + + +++E ++ ++ K ++ + I + Sbjct: 2517 NNKLKPSDQTDNDQLQKELMFQEIEGESPEDRNKRYLKAIEDK--FNEIIAKLQESINNQ 2574 Query: 940 IRDKKVLNEKYE--KNIE-YVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQ 996 + K L +K + IE + Q +A+L E K+N E E+ + N + + + Sbjct: 2575 NEELKKLRQKCDGVDAIELQLAQKKAELNEIKDNYEKEKAEREKEVEENNKKLKDTINAL 2634 Query: 997 QTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTK 1056 + + EQ ++IN ++ E+ A + I AQ S + +++ + K A + Sbjct: 2635 ENRLDSQGEQTRSKINSAEQTARKAKED--ADSAVI--AQKSLQAELNNLKQKYAVLEDQ 2690 Query: 1057 LENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELK-------ETKLTFEMNIPKT 1109 L+ +E Q+ ++QL + + + + + +++K+L+ E + NI + Sbjct: 2691 LKTEKENHQQEAQQLKELAEEDATPMVCIHVVGEKLKKLQNDNEKLSENNDNLQKNINEL 2750 Query: 1110 EGMI--ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTE 1167 + I + + + + +NV L+ E + +E L Q+ +L E Sbjct: 2751 KDKINGLEKQYKQDAAELSNVHHQLGALQEKATNLE-NENKSLKEENEDLMNQNKQLEKE 2809 Query: 1168 LQECYTKIIQLE---------TLNTELTGHDVVNQEQINQLKSKLEQL---NTENDNLLS 1215 Q+ + LE +N + D++ +QI+ LK +LE+L N++N+ L Sbjct: 2810 KQQLLAQNSNLEENKNNQEQSLMNRKKKNDDLL--KQIDDLKLELEELKRNNSQNETKLQ 2867 Query: 1216 TVAELRSSISSAV--DQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLL- 1272 + + + D+ + A+ L + + + L Q +E Y + Sbjct: 2868 NANQQIEMMKDQINNDKEQIKSAQDKLNDLQNKNNELNSNQIVLENQKKMYEGLYNDMKS 2927 Query: 1273 --DSVQSSTQEETNKIVTM----EQVTSLQ---NKLQDKEEHLRNLQ---EKYADVINQI 1320 D + +++T++I+ + +V++L+ +L + E L++ Q ++ QI Sbjct: 2928 SNDKLNDENRKKTDQIIDLTKQNAEVSALKLENQRLNSELEKLKSNQPVSSNDPELQKQI 2987 Query: 1321 EILRSE---IEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQL 1377 E L+ + + +EK + +S K M+EQ+ + + ++ Sbjct: 2988 EELKKQLNNLSNEKKQIETEKNGLQGQIGRLESQNESLIESKKDMKEQND-KLQAQMDEM 3046 Query: 1378 KKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENV 1437 ++ + N E KV LT QL +++ + + N++ N Sbjct: 3047 RRENNSLRQNQTQLERTNNGLENKVGNLTDQLNQVKNQL-SALQDQLKSKENENEKLRNE 3105 Query: 1438 RQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITE 1497 R++L + +E + +K++E+ +K+ +A H E+ KL ++ N K+ + Sbjct: 3106 REKLANEKNSVELQSKDKDAEI----IKLKSDAEHLNDKINSLNDEKNKL-QQANDKLND 3160 Query: 1498 SVSLNKQ----VAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSK 1553 + KQ + NK +E+E AK E ++N E ++ L +E + L++ + ++ Sbjct: 3161 QIEQMKQQINNLTNENKNMEQEKAKNQE---KIQNIEPKLKQLEEEKSKLEDENSQNENE 3217 Query: 1554 IQK 1556 IQ+ Sbjct: 3218 IQR 3220 Score = 132 bits (319), Expect = 8e-29 Identities = 248/1267 (19%), Positives = 508/1267 (40%), Gaps = 107/1267 (8%) Query: 146 HLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXX 205 +L N E L + K +E + ++++ E + EAK Sbjct: 3851 NLENEKAETQKLLEETEEAKKNLENEKAETEKRLQETE---EAKKNLANEKSEAERKLEE 3907 Query: 206 XXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSL----EEANKLLE 261 E T++++ + +E +E E K+E Q+ L++ E + L EEA K LE Sbjct: 3908 VQNEKAE-TERKLNEAEEANKNLENE-KNETQKKLEEAEQQKAETQKLLEQTEEAKKNLE 3965 Query: 262 AARFEIS-----LEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSL 316 + E E +K E E+ + ++ + ++ E E+ Sbjct: 3966 NEKSETEKKLQETEEAKKNLEQEKSDIQKKLDETKQQKVNLENEKAETQKLLEETEEAKK 4025 Query: 317 EIAN-MTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLI--SRK 373 + N E KK++ E + Q + E KL + E A+ + + + + K Sbjct: 4026 NLENEKAETQKKLDEAEEAKKNLEQEKSDAEKKLEEVQNEKSALENEKNETQKKLEEAEK 4085 Query: 374 SGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDT 433 + + + QL + ++K E +KL+ + L L D E +++K+ Sbjct: 4086 AKDQIVEEKSAVERQLVESQKDSSENQKQQDEEKSKLQQQLSDLQNKLNDLEKKLADKEN 4145 Query: 434 XXXXXXXXXXGKDTLIAQLQ-----LEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQE 488 + QLQ LE ++ + + N + +K Sbjct: 4146 EKEQEKTQKDDLQKQLDQLQKDFDNLEREKQKLQDKNDSMKETIDSKNMLLDSFGTIKDH 4205 Query: 489 LND-EIKDVNVKDLIEKLKSAEEQITQLNDE----IDAANKNMIKVKSNHKLKLKQMQKT 543 LND + ++D KL+ ++ T N+E ID N+ + + + K ++++ T Sbjct: 4206 LNDANNNNKKLQDENNKLRDDAQKATSKNNELQSIIDDLNRKLANLDAEKKATEEKLKNT 4265 Query: 544 IDNFSKVSDSNK---EIVRLTEELH-HLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVY 599 D + K + +R TE +K+A+ EEEK ++ L ++ + D Sbjct: 4266 EDKLKQAEAEKKATEDKLRETENAKKETEEKLAKTEEEKKQVEDKLAATEAAKKETEDKL 4325 Query: 600 KKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADIS--QLQSDQVCS 657 K+ + + E +L + E++K D+ Q + K + E++ A + + ++ Sbjct: 4326 KQTEDEKKATEDKLANV---EAEKSDIEQAKKETEDKLKQTEEEKAAVEAEKKATEDKLH 4382 Query: 658 EIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQEN 717 E + E + D L ++ E A V E K + E +K E +K+ NKL+ E Sbjct: 4383 ETEEAKKETE-DKLKQTEDEKAAV-EQAKKETED---KLKQTEEEKKATENKLEESEAEK 4437 Query: 718 MDLTDKLEKM--SAEK----ISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESEL 771 +L ++ E S EK + LL+K+ E ++ + + +++K+++ + + E +L Sbjct: 4438 KELGERFESSRGSTEKQVSDLENLLSKLKDELKNIKEDKSQLESKLKQAEAEKKATEDKL 4497 Query: 772 SKYKSRICRLEES-------IAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDEL- 823 +K + LE++ +A +E+ + + E + + L + QKA ++ ++++L Sbjct: 4498 AKTEVEKAALEQAKKETEDKLANVENEKKATETQKNDLAKEKTDLQKALAKLLKRQEQLD 4557 Query: 824 ------VNRLAVLMDHDRVVEKQLLEIEHENKELQKK-----NQILLEENQN------LQ 866 + L + E++L E E KE Q K + + E++ L+ Sbjct: 4558 AEKKALEEKANALESEKKATEEKLANAEKEKKETQDKLKQTEDNLAKSESEKKATEDKLK 4617 Query: 867 ISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIE 926 + S+ Q A E ++ AE+E + +L+ E K + Q +KK E E Sbjct: 4618 QTESEKAQIEAAKKETEDKLQNAENEKKAAEEKLKQSEEQKKATEEKLQEAEAEKKAEQE 4677 Query: 927 DL-EIEFNTQ-----IESAIRD--------KKVLNEKYEKNIEYVTQLEAQLQEYKNNIE 972 L IE Q E + D K++L + E + +L Q+ + + Sbjct: 4678 KLANIEAEKQQLGNASEKQVSDLSGEISKLKQLLKQLAEAKKKADEELAKSKQDKEQSDN 4737 Query: 973 NLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKI 1032 + + E+LN + +L D ++K + +S + + +NKL KQKD+EI L K Sbjct: 4738 DKSKLQEDLNNLKKQLED--LEKAKKESDSNNKLLADSVNKLKEQNKQKDDEIKNLTDKA 4795 Query: 1033 NNAQVSYMS----MVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQ 1088 N Q + V +L++ KLEN ++ ++ + + + ++ + E+ Sbjct: 4796 NQPQDINNNPDFVKVKKAFLQLSKTNEKLENEKKALEGAVNSIYSTMKKDDSAPL--DEK 4853 Query: 1089 DDQIKELKETKLTFEMNI-PKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEE 1147 +++ + K + N K + M+D N++ +K +E+ Sbjct: 4854 ATPMQQAERAKELIQNNSGKKVDPEFFEKLTNEMNDLFNSICKVFRTNSPITFDIKKEED 4913 Query: 1148 EEFIQERS-VLQEQSAKLNTELQECYTK-IIQLETLNTELTGHDVVNQEQINQLKSKLEQ 1205 I + S VL++ T+L K Q+ L + + N+E + + Sbjct: 4914 IATIGQNSIVLRKVMKSYLTQLSNDIIKDKQQISDLKHDKNSLQMENEEIKATASANMSS 4973 Query: 1206 LNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFE 1265 + ND L+ + ++ + + + + E E+ Q ++ E L + F Sbjct: 4974 KDINNDKLIKSYKKVYARMKQ-LQEAEREAKEILLLACPQLRSEI-NIEEGLVTFVKNFV 5031 Query: 1266 SKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRS 1325 +K+ L+ S+ ++ Q E I ++++ LQ+ + DK + +KY ++N+ + + Sbjct: 5032 TKFPVLIASL-AADQIERPFISLDQRISKLQSSV-DK------IIQKYEALVNRYSLAST 5083 Query: 1326 EIEDEKV 1332 E V Sbjct: 5084 ATNPEAV 5090 Score = 125 bits (301), Expect = 1e-26 Identities = 233/1129 (20%), Positives = 488/1129 (43%), Gaps = 126/1129 (11%) Query: 469 GTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQ--LNDEIDAANKNM 526 G + +E+ K E+LK+E N +K N +L ++L +QI + +N+ + Sbjct: 1849 GKEHKSPSELLKENEELKKE-NQRLKKENA-ELKKRLGIPVDQIIEGIMNESTASDESED 1906 Query: 527 IKVKSNHKLKLKQMQKTIDNFSK------VSDSNKEIVRLTEEL-HHLSQKVAELEEEKG 579 K K +++ ++K +++ V + N E+ + L L Q V E ++ Sbjct: 1907 NKSPEELKREIENLKKQLEDLKNSGSQENVDEENNEMKEGADNLIDALQQSVDEKNKQID 1966 Query: 580 NLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDE 639 +LQ L D + R IE + K+ ++EN+ E ++ S + D+ E ++ ++ +E Sbjct: 1967 DLQQKLDDQN--REIEL-LKAKVEQIENINEEEDNEDIVVASTR-DVELE-NVEEESPEE 2021 Query: 640 VEDKLAD-ISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKD 698 +++LA+ ISQLQ + S+ +++ + + A +L IE +K +KE ++ Sbjct: 2022 AKERLAEQISQLQDKLTEKKKNSLQMKQALASKDAEISKLNEEIEQIKSEKEDQDKELEK 2081 Query: 699 LENDKEDIMNKLQN------YIQEN---MDLTDKLEKMSAEKISELLAKINHEEQSKIQT 749 L N+ + + KL+N Q N D D +EK+ E+ E L N +++ Sbjct: 2082 LNNELTEALEKLENGKKKSSQEQNNENEEDFVDDIEKLKEER--ENLKSENESLKNQAPE 2139 Query: 750 QFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLE---RKADQLGSYL 806 G+ ++ +++ +++I LE I+ ++ LE + D+ L Sbjct: 2140 NEGLKKSLENLKKSNDDLNKSNEDKENKIKELESEISKLKSEINELEQNNKDKDREIEIL 2199 Query: 807 QEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQ 866 K + + +DE + + V+ D V++ + + E + K + E N N Sbjct: 2200 SSKVSSIENVNLDDDE--DDITVVGTRDISVDETI----PTDNETETKTE--PETNTNTN 2251 Query: 867 ISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIE 926 + ++ + N ++ N + +S+ K + +++ L+ L+ K+ E++ Sbjct: 2252 ENTNETNEE-NVSSQEGNNEEKNQSKEDKKKLRIQQLKQ-----------LLASKQGEVD 2299 Query: 927 DLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNL 986 L +S D K NE K+ +L + +E + IEN+N N E Sbjct: 2300 AL--------KSQNDDLKSENETLSKSNH---ELGTKTKELEEEIENINNNKEGEVIDEK 2348 Query: 987 ELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDY 1046 E D V T+ D+ + N+ L +LLK K E+ L QK N A+ ++ +++ Sbjct: 2349 EASDVEV-VCSTRDVDFEYENENDPETLKSLLKSKLSELENL-QKENKAKEDEITKLNEE 2406 Query: 1047 ESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNI 1106 +K K + E +R++ ++ + H+E L EQ+ + K +++ + + Sbjct: 2407 LAKSED--AKRRELAETAERLNNEI--NTLHDE----LQNEQNARQKLIEDLQ-SNNKEP 2457 Query: 1107 PKTEGMIISSTIEPMSDDANN-VDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLN 1165 K + + +E SD+ N ++ L+ +E E+ Q LQ+Q A LN Sbjct: 2458 EKDDNGDFMNVLEKKSDEINKALEEILHRQNEEIKALRDREAEKNKQTVDDLQKQIAMLN 2517 Query: 1166 TELQ---ECYTKIIQLETLNTELTGHDVVN---------QEQINQLKSKL-EQLNTENDN 1212 +L+ + +Q E + E+ G + +++ N++ +KL E +N +N+ Sbjct: 2518 NKLKPSDQTDNDQLQKELMFQEIEGESPEDRNKRYLKAIEDKFNEIIAKLQESINNQNEE 2577 Query: 1213 L--LSTVAELRSSISSAVDQRGFEIAEL---WKQHLAQREADFQKTEHELRVQLSAFESK 1267 L L + +I + Q+ E+ E+ +++ A+RE + ++ +L+ ++A E++ Sbjct: 2578 LKKLRQKCDGVDAIELQLAQKKAELNEIKDNYEKEKAEREKEVEENNKKLKDTINALENR 2637 Query: 1268 YEQLLDSVQS--STQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRS 1325 + + +S ++ E+T + E S + + L NL++KYA + +Q++ + Sbjct: 2638 LDSQGEQTRSKINSAEQTAR-KAKEDADSAVIAQKSLQAELNNLKQKYAVLEDQLKTEKE 2696 Query: 1326 EIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXX 1385 + E + + K++Q + ++E N L+K+ Sbjct: 2697 NHQQE----AQQLKELAEEDATPMVCIHVVGEKLKKLQNDN-EKLSENNDNLQKN----- 2746 Query: 1386 XXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYE 1445 +N+ + K+ L Q + +D+ H L ++ EN + L E Sbjct: 2747 ---------INELKDKINGLEKQYK-QDAAELSNVHHQLGALQEKATNLENENKSLKEEN 2796 Query: 1446 KRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQV 1505 + + + + E E L L + N + Q++S + R K ++ L KQ+ Sbjct: 2797 EDLMNQNKQLEKEKQQL-LAQNSNLEENKNNQEQSLMNRKK----------KNDDLLKQI 2845 Query: 1506 AELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKI 1554 +L LEE ++ +T L+N +I + D+I N + ++++ K+ Sbjct: 2846 DDLKLELEELKRNNSQNETKLQNANQQIEMMKDQINNDKEQIKSAQDKL 2894 Score = 120 bits (289), Expect = 3e-25 Identities = 283/1336 (21%), Positives = 555/1336 (41%), Gaps = 144/1336 (10%) Query: 261 EAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIAN 320 E RF+I S+ QEL + + + + +IEEK + Sbjct: 32 EIDRFDIDSISSRPLQELAELAYDKNEKISSK--VVNSMADQFAVYERQIEEKTETILQQ 89 Query: 321 MTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTAS 380 E+ ++ + + + ELE + A S+ ++S PL R G + Sbjct: 90 NNEIDSL--RAKYNDARAKSAAYELELQKAKQSLISRTINSNIH---PL--RSIGHDLED 142 Query: 381 KMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXX 440 + +S +SS D + + +E+++L+ S N +LV + + T Sbjct: 143 EKESLSDSISSTISIYDENLESLNDELSRLKQ--NSQNSELVK----VLDNLTRTTDYVV 196 Query: 441 XXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKD 500 + L + Q + + + T +N A++QE + +I K+ Sbjct: 197 NLENNENLERYTTYDAQLRAISQAALRLSTKVNSLN--AELQELKHSQSEMQIIVSQYKE 254 Query: 501 LIEKLK---SAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEI 557 ++ K+ E++ +ND D +KN + K ++Q+ DN K +NKE+ Sbjct: 255 VVPKISFHIETIEKLVSINDT-DEDDKNPLIFPQRLKRIRSEVQRLFDNNEK---TNKEL 310 Query: 558 VRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAIS 617 +L E+L EL E N Q R E + + +E +N +LKA Sbjct: 311 QKLKEQL--------ELYENMKNGQSM-----KERQAELESLRLELEKKNAELEQLKA-R 356 Query: 618 LLESQKFDLVQELHILQQKYDEVEDKLADI-SQLQSDQVCS---EIKSVHLEEQIDALSA 673 Q L+ E+ ++ + +++K+AD SQ+++ + + +E I+ L Sbjct: 357 YQSKQDPQLLAEIERIENEVQNLKNKIADRESQIKALNLLIAQYQTDDEDKKEIIENLEK 416 Query: 674 SKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNK-LQNYIQENMDLTD----KLEKMS 728 K+L IE+ + E L I +E ED ++ + ++DL D + E++S Sbjct: 417 EIKDLKKQIEDKDKEIEVLKAKIAKIEEIPEDEEDEDIVVAGTRDVDLGDFNEEEAEQVS 476 Query: 729 AE-KISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAV 787 E ++ +L K++ ++++ +Q + + +K D IE + ++ + K R + E++I Sbjct: 477 LEDQVKQLKEKLDDKKKNGVQMKQALASK----DAEIEKLNEQIQELKDRNDKQEQNIEE 532 Query: 788 MEDRRYSLERKADQLGSYLQEKQ---KAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEI 844 + + L+ D+ + E Q K ++ + +L N D ++ E + E Sbjct: 533 LNTKNSDLQNSNDEYKKLIDELQNQLKDLAKNKAESSDLNNSENTKQDSEKA-EDENAET 591 Query: 845 EHENKELQKKNQILLEENQNLQISLSDMQQHYNAL----VEKANRTDLAESESTKYQTQL 900 + NKELQ+++ L EN+ L+ SL ++++ + L +K N+ ESE +K ++++ Sbjct: 592 K-SNKELQEESDKLKSENEGLKKSLENLKKSNDDLNKSNEDKENKIKELESEISKLKSEI 650 Query: 901 RDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQL 960 +LE N K E + ++ K IE++ ++ + + + + + ++ I + Sbjct: 651 NELEQNNKDKDREIE-ILSSKVSSIENVNLDDDEDDITVVGTRDI---SVDETIPTDNET 706 Query: 961 EAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQ 1020 E + + N N N N E N+ N+ + + +++ QS + ++ I +L LL Sbjct: 707 ETKTEPETNT--NTNENTNETNEENVSSQEGN-NEEKNQSKEDKKKL--RIQQLKQLLAS 761 Query: 1021 KDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSK----QLLDSKQ 1076 K E+ AL + N+ S +S +L TK + +EEE++ ++ +++D K+ Sbjct: 762 KQGEVDALKSQ-NDDLKSENETLSKSNHELE---TKNKELEEEIENINNNKEGEVIDEKE 817 Query: 1077 HNE-ELQILVREQD---------DQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDAN 1126 ++ E+ R+ D + +K L ++KL+ N+ K E + IE + ++ Sbjct: 818 ASDVEVVCSTRDVDFEYENENDPETLKSLLKSKLSELENLQK-ENTDLMKQIEELKNENE 876 Query: 1127 NVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELT 1186 N+ LK E E +Q + QS EL +I QLE+L EL Sbjct: 877 NLKRELENLKLENESLK--RENERLQLTADQSPQSKDKMIELLA--NQINQLESLVPELQ 932 Query: 1187 GHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQR 1246 +I +LK + +Q+ EN+ L +L+ S S+ + + Q Sbjct: 933 Q----KTNEIEELKKENKQIKEENEKLKKENEDLKKSGSNKS-----------SEEINQE 977 Query: 1247 EADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHL 1306 E D +K +L+ L + E S EE K V E + D +EH Sbjct: 978 EEDLKKQIEDLKKALGYPQDGKEHKTPSELIEENEELKKKV--EDLEKESGYPSDNKEH- 1034 Query: 1307 RNLQEKYADVINQIEILRSEIEDEKVAF----XXXXXXXXXXXXXXXXDLRTENQSYKQ- 1361 + ++++ + E L+ +++D + A +L+ +N + K+ Sbjct: 1035 ----KSPSELLKENEELKKKVDDLEKALGYPEDGKDHKSPSELIKENEELKKQNDALKRA 1090 Query: 1362 -------MQEQSILNINEENAQLKKS-SXXXXXXXXXXXXRVNDAEAKVLELTHQLELKD 1413 +S + +EN +LKK + + + +++L +L+ K Sbjct: 1091 LGYPEDGKDHKSPSELIQENEELKKKVADLEKALGYPADGQEHKTPSELLRENEELK-KK 1149 Query: 1414 SEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYE-------KESELAILRLKM 1466 I T T + + N E +R + + +K+IEDL KE + +K Sbjct: 1150 LGISDST---TPSDNEDNKSPEELRSENKDLKKQIEDLKRALGYPEDGKEHKTPSELIKE 1206 Query: 1467 HENANHYETMQKES--EIERVKLIEELNVKITESVSLNKQVAELNKALE-EEVAKTNEMQ 1523 +E K++ E K + + I E+ L K+V +L KAL E K ++ Sbjct: 1207 NEELKKQNDSLKKALGYSEDGKDHKSPSELIKENEDLKKKVEDLEKALGFPEDGKEHKTP 1266 Query: 1524 TAL--ENQEIEIVTLN 1537 + L EN+E++ T N Sbjct: 1267 SELIKENEELKEETEN 1282 Score = 100 bits (240), Expect = 3e-19 Identities = 178/898 (19%), Positives = 380/898 (42%), Gaps = 74/898 (8%) Query: 696 IKDLENDKEDIMNKLQNYIQENMDLT-DKLEKMSAEKISELL-------AKINHEEQSKI 747 + + E D+ DI + +QE +L DK EK+S++ ++ + +I + ++ + Sbjct: 28 LNEEEIDRFDIDSISSRPLQELAELAYDKNEKISSKVVNSMADQFAVYERQIEEKTETIL 87 Query: 748 QTQFGID---AKIQERDLYIENIESELSKYK-SRICR-LEESIAVMEDRRYSLERKADQL 802 Q ID AK + E EL K K S I R + +I + + LE + + L Sbjct: 88 QQNNEIDSLRAKYNDARAKSAAYELELQKAKQSLISRTINSNIHPLRSIGHDLEDEKESL 147 Query: 803 GSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEEN 862 + Y E ++ ++RL + +V+ + + +N LE Sbjct: 148 SDSISSTISIYDENLESLNDELSRLKQNSQNSELVKVLDNLTRTTDYVVNLENNENLERY 207 Query: 863 QNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLI--VQ 920 L + Q L K N + E Q++++ + S K + + I ++ Sbjct: 208 TTYDAQLRAISQAALRLSTKVNSLNAELQELKHSQSEMQIIVSQYKEVVPKISFHIETIE 267 Query: 921 KKKEIEDLEIEFNTQIESAIRDKKVLNE------KYEKNIEYVTQLEAQLQEYKN--NIE 972 K I D + + + R K++ +E EK + + +L+ QL+ Y+N N + Sbjct: 268 KLVSINDTDEDDKNPLIFPQRLKRIRSEVQRLFDNNEKTNKELQKLKEQLELYENMKNGQ 327 Query: 973 NLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKI 1032 ++ EL + LEL K+ + +Q ++ ++Q +L A +++ + E+ L KI Sbjct: 328 SMKERQAELESLRLELEKKNAELEQLKARYQSKQD----PQLLAEIERIENEVQNLKNKI 383 Query: 1033 NNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQI 1092 + + S + +AQ+ T E+ +E ++ + K++ D K+ E+ ++++ ++ Sbjct: 384 ADRE----SQIKALNLLIAQYQTDDEDKKEIIENLEKEIKDLKKQIED-----KDKEIEV 434 Query: 1093 KELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQ---EEEE 1149 + K K+ + E ++++ T + D N + LK + +++ Sbjct: 435 LKAKIAKIEEIPEDEEDEDIVVAGTRDVDLGDFNEEEAEQVSLEDQVKQLKEKLDDKKKN 494 Query: 1150 FIQERSVLQEQSA---KLNTELQECYTK-------IIQLETLNTELTGHDVVNQEQINQL 1199 +Q + L + A KLN ++QE + I +L T N++L + ++ I++L Sbjct: 495 GVQMKQALASKDAEIEKLNEQIQELKDRNDKQEQNIEELNTKNSDLQNSNDEYKKLIDEL 554 Query: 1200 KSKLEQL--NTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHEL 1257 +++L+ L N + L+ + A D+ AE Q E+D K+E+E Sbjct: 555 QNQLKDLAKNKAESSDLNNSENTKQDSEKAEDEN----AETKSNKELQEESDKLKSENE- 609 Query: 1258 RVQLSAFESKYEQLLDSVQSSTQEETNKIVTME-QVTSLQNKLQDKEEHLRNLQEKYADV 1316 L ++ D + S +++ NKI +E +++ L++++ + E++ ++ + + Sbjct: 610 --GLKKSLENLKKSNDDLNKSNEDKENKIKELESEISKLKSEINELEQNNKDKDREIEIL 667 Query: 1317 INQIEILRS-EIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENA 1375 +++ + + ++D++ D TE ++ + + N NE N Sbjct: 668 SSKVSSIENVNLDDDEDDITVVGTRDISVDETIPTDNETETKTEPETNTNTNENTNETNE 727 Query: 1376 QLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQ-KTHEYTI-----TLTQ 1429 + S + + + ++ +L L K E+ K+ + TL++ Sbjct: 728 E--NVSSQEGNNEEKNQSKEDKKKLRIQQLKQLLASKQGEVDALKSQNDDLKSENETLSK 785 Query: 1430 RNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHEN---ANHYETMQKESEIERVK 1486 N E E ++L E+ IE++ KE E+ + + + E+E + Sbjct: 786 SNHELETKNKEL---EEEIENINNNKEGEVIDEKEASDVEVVCSTRDVDFEYENENDPET 842 Query: 1487 LIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQ 1544 L L K++E +L K+ +L K +EE + ++ LEN ++E +L E LQ Sbjct: 843 LKSLLKSKLSELENLQKENTDLMKQIEELKNENENLKRELENLKLENESLKRENERLQ 900 Score = 92.7 bits (220), Expect = 8e-17 Identities = 237/1200 (19%), Positives = 480/1200 (40%), Gaps = 103/1200 (8%) Query: 168 METTILDLQEKINEKD---QIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQEN 224 +E I DL+++I +KD ++++AK + + + Sbjct: 414 LEKEIKDLKKQIEDKDKEIEVLKAKIAKIEEIPEDEEDEDIVVAGTRDVDLGDFNEEEAE 473 Query: 225 FIAMEAEWKDEKQRL----LKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQ 280 +++E + K K++L ++ K S E KL E + E+ + K Q +E+ Sbjct: 474 QVSLEDQVKQLKEKLDDKKKNGVQMKQALASKDAEIEKLNEQIQ-ELKDRNDKQEQNIEE 532 Query: 281 XXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKK-IELLEHLNCQIR 339 K E + K + K N +E TK+ E E N + + Sbjct: 533 LNTKNSDLQNSNDEYKKLIDELQNQLKDLAKNKAESSDLNNSENTKQDSEKAEDENAETK 592 Query: 340 QTNKELENKLATMGTES----KAVSSPSKKGSPL-ISRKSGRNTASKMKSPWSQLSSETL 394 +NKEL+ + + +E+ K++ + K L S + N +++S S+L SE Sbjct: 593 -SNKELQEESDKLKSENEGLKKSLENLKKSNDDLNKSNEDKENKIKELESEISKLKSEIN 651 Query: 395 NQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQL 454 + + K EI L + S+ +D ++D +T+ + Sbjct: 652 ELEQNNKDKDREIEILSSKVSSIENVNLD-----DDEDDITVVGTRDISVDETIPTDNET 706 Query: 455 EHQQHMEGPSLIHVGTNTEDVNEIAKVQ--EQLKQELNDEIKDVNVKDLIEKLKSAEEQI 512 E + E + + TN + ++ + + K + ++ K + ++ L + L S + ++ Sbjct: 707 ETKTEPETNTNTNENTNETNEENVSSQEGNNEEKNQSKEDKKKLRIQQLKQLLASKQGEV 766 Query: 513 TQL---NDEIDAANKNMIKVKSNHKL--KLKQMQKTIDNFSKVSDSNKEIVRLTEELHHL 567 L ND++ + N+ + KSNH+L K K++++ I+N ++NKE E + Sbjct: 767 DALKSQNDDLKSENETL--SKSNHELETKNKELEEEIENI----NNNKE----GEVIDEK 816 Query: 568 SQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETR---LKAISLLESQKF 624 E+ ++ + + ++S + K+ E+ENL + +K I L+++ Sbjct: 817 EASDVEVVCSTRDVDFEYENENDPETLKSLLKSKLSELENLQKENTDLMKQIEELKNENE 876 Query: 625 DLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIEN 684 +L +EL L+ + + ++ + + QL +DQ ++ I+ L+ +L E+ Sbjct: 877 NLKRELENLKLENESLKRENERL-QLTADQ-----SPQSKDKMIELLANQINQL----ES 926 Query: 685 LKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQ 744 L + +Q I++L+ + + I + + +EN DL S+E+I++ + + + Sbjct: 927 LVPELQQKTNEIEELKKENKQIKEENEKLKKENEDLKKSGSNKSSEEINQEEEDLKKQIE 986 Query: 745 SKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGS 804 ++ G +E E IE E + K ++ LE+ D + E K+ Sbjct: 987 D-LKKALGYPQDGKEHKTPSELIE-ENEELKKKVEDLEKESGYPSDNK---EHKSP---- 1037 Query: 805 YLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQIL-----L 859 E K E + D+L L D K E+ EN+EL+K+N L Sbjct: 1038 --SELLKENEELKKKVDDLEKALG--YPEDGKDHKSPSELIKENEELKKQNDALKRALGY 1093 Query: 860 EENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIV 919 E+ S S++ Q L +K DL ++ Q S L R E + Sbjct: 1094 PEDGKDHKSPSELIQENEELKKKV--ADLEKALGYPADGQEHKTPSELLRENEE-----L 1146 Query: 920 QKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQ---LEAQLQEYKNNIENLNM 976 +KK I D + + + + + N+ +K IE + + +E+K E + Sbjct: 1147 KKKLGISDSTTPSDNEDNKSPEELRSENKDLKKQIEDLKRALGYPEDGKEHKTPSELIKE 1206 Query: 977 NVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEI-IALNQKINNA 1035 N EEL K N L K D+ +E+ K N LK+K E++ AL + Sbjct: 1207 N-EELKKQNDSL--KKALGYSEDGKDHKSP--SELIKENEDLKKKVEDLEKALGFPEDGK 1261 Query: 1036 QVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQIL-----VREQDD 1090 + S + +L + T ++ E+++R D K+H +++ +++Q++ Sbjct: 1262 EHKTPSELIKENEELKEETENIKKQIEDLKRALGYPEDGKEHKTPSELINENEELKKQNE 1321 Query: 1091 QIKELKETKLTFEMNIPKTEGMIISSTIEPMSDD-ANNVDXXXXXXXXXXXXLKVQEEEE 1149 +K K+ ++ E + K++ I+ + + ++ + + E Sbjct: 1322 NLK--KKLGISGESSTDKSDSNKTPEEIKQENGELKKQIEDLKKALGYPEDGKEHKSPSE 1379 Query: 1150 FIQERSVLQEQSAKLNTEL-----QECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLE 1204 I+E L++Q+ L L + + +L N EL ++ E + E Sbjct: 1380 LIKENEELKKQNDDLKRALGYPEDGKDHKTPSELIKENEELKKKLGISGESSTEESKSYE 1439 Query: 1205 QLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAF 1264 +L ++L V +L ++ D + + L + + +K +L+ L Sbjct: 1440 ELKDLINDLKKKVEDLEKALGYPSDGKDHKS----PSELLKENDELKKQNDDLKKALGYP 1495 Query: 1265 ESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILR 1324 E E S EE K + + + +S +K +K L+ + ++ QIE L+ Sbjct: 1496 EDGKEHKSPSELIKENEELKKKLGLSEESSTDSKADNKSP--EELKNENNELKKQIEALK 1553 Score = 91.1 bits (216), Expect = 2e-16 Identities = 284/1387 (20%), Positives = 562/1387 (40%), Gaps = 137/1387 (9%) Query: 223 ENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXX 282 E +++ +D+K L+ K +R E +L + + + E KL ++LE Sbjct: 267 EKLVSINDTDEDDKNPLIFPQRLKRIR----SEVQRLFDNNE-KTNKELQKLKEQLELYE 321 Query: 283 XXXXXXXXXXXXLAKQSIEPSCEEKT-EIEE-KGSLEIANMTELTKKIELLEHLNCQIRQ 340 +S+ E+K E+E+ K + +L +IE +E+ Sbjct: 322 NMKNGQSMKERQAELESLRLELEKKNAELEQLKARYQSKQDPQLLAEIERIEN------- 374 Query: 341 TNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDK 400 + L+NK+A ++ KA++ + + + ++ L + ++D + Sbjct: 375 EVQNLKNKIADRESQIKALNLLIAQYQT--DDEDKKEIIENLEKEIKDLKKQIEDKDKEI 432 Query: 401 KINKNEIAKLEMVIQSLNKDLVDKEYVIS-EKDTXXXXXXXXXXGKDTL---IAQLQLEH 456 ++ K +IAK+E + +D D++ V++ +D + +L + QL+ + Sbjct: 433 EVLKAKIAKIE----EIPEDEEDEDIVVAGTRDVDLGDFNEEEAEQVSLEDQVKQLKEKL 488 Query: 457 QQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELND--EIKDVNVKDLIEK---LKSAEEQ 511 + + ++D EI K+ EQ+ QEL D + ++ N+++L K L+++ ++ Sbjct: 489 DDKKKNGVQMKQALASKDA-EIEKLNEQI-QELKDRNDKQEQNIEELNTKNSDLQNSNDE 546 Query: 512 ITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKV 571 +L DE+ K++ K K+ L + T + K D N E + +EL S K+ Sbjct: 547 YKKLIDELQNQLKDLAKNKAESS-DLNNSENTKQDSEKAEDENAE-TKSNKELQEESDKL 604 Query: 572 -AELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQEL 630 +E E K +L+ D D K+ E+E+ I+ LE D +E+ Sbjct: 605 KSENEGLKKSLENLKKSNDDLNKSNEDKENKIKELESEISKLKSEINELEQNNKDKDREI 664 Query: 631 HILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKE 690 IL K +E+ ++ + D + + ++E I + ++ K + E Sbjct: 665 EILSSKVSSIEN--VNLDDDEDDITVVGTRDISVDETIPTDNETET---------KTEPE 713 Query: 691 QLYGTIKDL-ENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQT 749 T ++ E ++E++ ++ N ++N DK +K+ +++ +LLA E +++ Sbjct: 714 TNTNTNENTNETNEENVSSQEGNNEEKNQSKEDK-KKLRIQQLKQLLAS-KQGEVDALKS 771 Query: 750 QFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSL---ERKADQLGSYL 806 Q D K + L N E E +K K LEE I + + + E++A + Sbjct: 772 Q-NDDLKSENETLSKSNHELE-TKNKE----LEEEIENINNNKEGEVIDEKEASDVEVVC 825 Query: 807 QEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQ 866 + + EY + D L L+ +L ++ EN +L K+ + L EN+NL+ Sbjct: 826 STRDVDF-EYENENDP--ETLKSLLKSKL---SELENLQKENTDLMKQIEELKNENENLK 879 Query: 867 ISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIE 926 L +++ +L + R L +S + + ++ +L +N + QK EIE Sbjct: 880 RELENLKLENESLKRENERLQLTADQSPQSKDKMIELLANQINQLESLVPELQQKTNEIE 939 Query: 927 DLEIEFNTQIESAIRDKKVLNEKYEK--NIEYVTQLEAQLQEYKNNIENLNMNV-----E 979 +L+ E N QI+ K NE +K + + ++ + ++ K IE+L + Sbjct: 940 ELKKE-NKQIKEENEKLKKENEDLKKSGSNKSSEEINQEEEDLKKQIEDLKKALGYPQDG 998 Query: 980 ELNKMNLELIDKHVQ-KQQTQSPDYTEQY--INEINKLNALLKQKDEEIIALNQKINNAQ 1036 + +K ELI+++ + K++ + + Y N+ +K + L +++EE L +K+++ + Sbjct: 999 KEHKTPSELIEENEELKKKVEDLEKESGYPSDNKEHKSPSELLKENEE---LKKKVDDLE 1055 Query: 1037 --VSYMSMVSDYE--SKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQI 1092 + Y D++ S+L + +L+ + ++R D K H + L++E ++ Sbjct: 1056 KALGYPEDGKDHKSPSELIKENEELKKQNDALKRALGYPEDGKDHKSPSE-LIQENEELK 1114 Query: 1093 KELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQ 1152 K++ + + E S + + + K EE Sbjct: 1115 KKVADLEKALGYPADGQEHKTPSELLRENEELKKKLGISDSTTPSDNEDNK--SPEELRS 1172 Query: 1153 ERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKL--------- 1203 E L++Q L L Y + + +EL + ++Q + LK L Sbjct: 1173 ENKDLKKQIEDLKRALG--YPEDGKEHKTPSELIKENEELKKQNDSLKKALGYSEDGKDH 1230 Query: 1204 ---EQLNTENDNLLSTVAELRSSISSAVDQRGFEI-AELWKQH--LAQREADFQKTEHEL 1257 +L EN++L V +L ++ D + + +EL K++ L + + +K +L Sbjct: 1231 KSPSELIKENEDLKKKVEDLEKALGFPEDGKEHKTPSELIKENEELKEETENIKKQIEDL 1290 Query: 1258 RVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQE--KYAD 1315 + L E E S + EE K Q +L+ KL E + + K + Sbjct: 1291 KRALGYPEDGKEHKTPSELINENEELKK-----QNENLKKKLGISGESSTDKSDSNKTPE 1345 Query: 1316 VINQIE-ILRSEIEDEKVAF----XXXXXXXXXXXXXXXXDLRTENQSYKQ--------M 1362 I Q L+ +IED K A +L+ +N K+ Sbjct: 1346 EIKQENGELKKQIEDLKKALGYPEDGKEHKSPSELIKENEELKKQNDDLKRALGYPEDGK 1405 Query: 1363 QEQSILNINEENAQLKK-------SSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSE 1415 ++ + +EN +LKK SS +ND + KV +L L Sbjct: 1406 DHKTPSELIKENEELKKKLGISGESSTEESKSYEELKDLINDLKKKVEDLEKALGYPSD- 1464 Query: 1416 IYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIED-LTYEKESELAILRLKMHENANHYE 1474 K H+ L + NDE + L + ED ++ SEL ++ + E Sbjct: 1465 --GKDHKSPSELLKENDELKKQNDDLKKALGYPEDGKEHKSPSELIKENEELKKKLGLSE 1522 Query: 1475 TMQKESEIERVKLIEELNVKITESVSLNKQVAELNKAL-EEEVAKTNEMQTALENQEIEI 1533 +S+ + K EEL E+ L KQ+ L + L E ++ + L + E+ Sbjct: 1523 ESSTDSKADN-KSPEELK---NENNELKKQIEALKRVLGYPEDGNEHKTPSELIKENEEL 1578 Query: 1534 VTLNDEI 1540 ND + Sbjct: 1579 KKQNDNL 1585 Score = 91.1 bits (216), Expect = 2e-16 Identities = 267/1338 (19%), Positives = 551/1338 (41%), Gaps = 118/1338 (8%) Query: 297 KQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATM--GT 354 K+ +E E+ E G E +EL K+ E L+ I++ ++L+ L G Sbjct: 1244 KKKVE-DLEKALGFPEDGK-EHKTPSELIKENEELKEETENIKKQIEDLKRALGYPEDGK 1301 Query: 355 ESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVI 414 E K S + L +K N K+ + ++ + T ++I K E +L+ I Sbjct: 1302 EHKTPSELINENEEL--KKQNENLKKKLGISGESSTDKSDSNKTPEEI-KQENGELKKQI 1358 Query: 415 QSLNKDLVDKEYVISEKDTXXXXXXXXXXGK--DTLIAQLQL--EHQQHMEGPSLIHVGT 470 + L K L E K K D L L + + H LI Sbjct: 1359 EDLKKALGYPEDGKEHKSPSELIKENEELKKQNDDLKRALGYPEDGKDHKTPSELIKENE 1418 Query: 471 NTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVK 530 + I+ + + +E+KD+ + DL +K++ E+ + +D D + + + +K Sbjct: 1419 ELKKKLGISGESSTEESKSYEELKDL-INDLKKKVEDLEKALGYPSDGKDHKSPSEL-LK 1476 Query: 531 SNHKLKLKQ--MQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDY 588 N +LK + ++K + + + +K L +E L +K+ EE + + D Sbjct: 1477 ENDELKKQNDDLKKAL-GYPEDGKEHKSPSELIKENEELKKKLGLSEESSTDSK---ADN 1532 Query: 589 DSGRMIESDVYKKMIEMENLAETRLKAISLLESQK-FDLVQELHILQQKYDEVEDKLADI 647 S ++++ + ++E L E + +L++E L+++ D ++ L Sbjct: 1533 KSPEELKNENNELKKQIEALKRVLGYPEDGNEHKTPSELIKENEELKKQNDNLKRALGYP 1592 Query: 648 SQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKE-----QLYGTIKDLEND 702 + + SE+ + +I+ L +L + + DK+ +L ++L+ + Sbjct: 1593 EDGKDHKSPSELIA-----EIEELKKENDDLKRALGYPEDDKDHKSPSELIKENEELKKE 1647 Query: 703 KEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKI-QTQFGIDAKIQERD 761 +D+ +L + + + ++ E++ ++I +L + + E K +T + + +E Sbjct: 1648 NDDLKKRLGISGESSAEESNSPEELK-KQIEDLKKALGYPEDGKEHKTPSELIKENEELK 1706 Query: 762 LYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQ-----KAYSEY 816 + ++ L + S + E+ L++K + L L Q K+ SE Sbjct: 1707 KQNDALKRALGYPEDGKDHKSPSELIQENEE--LKKKVEDLEKALGYPQDGKDHKSPSEL 1764 Query: 817 TIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQK-----KNQILLEENQNLQISLSD 871 + +EL +L + + K E+++ENK L+K K + E+ S S+ Sbjct: 1765 LKENEELKKKLGISDESSTEDNKSPEELKNENKYLKKQIEGLKKALGYPEDGKEHKSPSE 1824 Query: 872 MQQHYNALVEKANRTD--LAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLE 929 + Q L +K + + L E K +L + + E+Q L + + + L Sbjct: 1825 LIQENEDLKKKVSDLEKALGYPEDGKEHKSPSELLKENEELKKENQRLKKENAELKKRLG 1884 Query: 930 IEFNTQI-----ESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKN--NIENLNMNVEELN 982 I + I ES D+ N+ E+ + L+ QL++ KN + EN++ E+ Sbjct: 1885 IPVDQIIEGIMNESTASDESEDNKSPEELKREIENLKKQLEDLKNSGSQENVDEENNEMK 1944 Query: 983 KMNLELIDKHVQK--QQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYM 1040 + LID Q ++ + D +Q +++ N+ LLK K E+I +N++ +N + + Sbjct: 1945 EGADNLIDALQQSVDEKNKQIDDLQQKLDDQNREIELLKAKVEQIENINEEEDNEDI-VV 2003 Query: 1041 SMVSDYESKLAQFTTKLENMEEEMQRVSKQL--LDSKQHNEELQILVREQDDQIKELKET 1098 + D E + + E+ EE +R+++Q+ L K ++ L +Q K+ + + Sbjct: 2004 ASTRDVELE----NVEEESPEEAKERLAEQISQLQDKLTEKKKNSLQMKQALASKDAEIS 2059 Query: 1099 KLTFEMNIPKTEGMIISSTIEPMSDDANN-VDXXXXXXXXXXXXLKVQEEEEFIQERSVL 1157 KL E+ K+E +E ++++ ++ + EE+F+ + L Sbjct: 2060 KLNEEIEQIKSEKEDQDKELEKLNNELTEALEKLENGKKKSSQEQNNENEEDFVDDIEKL 2119 Query: 1158 QEQSAKLNTELQECYTKIIQLETLNTEL----TGHDVVNQEQINQLKSKLEQLNTENDNL 1213 +E+ L +E + + + E L L +D +N+ ++ ++K+++L +E L Sbjct: 2120 KEERENLKSENESLKNQAPENEGLKKSLENLKKSNDDLNKSNEDK-ENKIKELESEISKL 2178 Query: 1214 LSTVAELRSSISS---AVDQRGFEIAELWKQHLAQREADFQKT-EHELRVQL-----SAF 1264 S + EL + ++ +++ + +L E D ++ V + Sbjct: 2179 KSEINELEQNNKDKDREIEILSSKVSSIENVNLDDDEDDITVVGTRDISVDETIPTDNET 2238 Query: 1265 ESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEE----HLRNLQEKYADVINQI 1320 E+K E ++ + ETN+ Q + + K Q KE+ ++ L++ A ++ Sbjct: 2239 ETKTEPETNTNTNENTNETNEENVSSQEGNNEEKNQSKEDKKKLRIQQLKQLLASKQGEV 2298 Query: 1321 EILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKS 1380 + L+S+ +D K + +L E ++ +E + I+E+ A Sbjct: 2299 DALKSQNDDLK-SENETLSKSNHELGTKTKELEEEIENINNNKEGEV--IDEKEA---SD 2352 Query: 1381 SXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQ 1440 N+ + + L+ + +L + E QK ++ + DE + ++ Sbjct: 2353 VEVVCSTRDVDFEYENENDPETLKSLLKSKLSELENLQKENK------AKEDEITKLNEE 2406 Query: 1441 LVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEEL--NVKITES 1498 L + E K ELA +++ N + + R KLIE+L N K E Sbjct: 2407 LAKSED-------AKRRELAETAERLNNEINTLHDELQNEQNARQKLIEDLQSNNKEPEK 2459 Query: 1499 VS-------LNKQVAELNKALEEEVAKTNEMQTALENQEIE-----IVTLNDEITNLQNM 1546 L K+ E+NKALEE + + NE AL ++E E + L +I L N Sbjct: 2460 DDNGDFMNVLEKKSDEINKALEEILHRQNEEIKALRDREAEKNKQTVDDLQKQIAMLNNK 2519 Query: 1547 VRAS----SSKIQKHVSF 1560 ++ S + ++QK + F Sbjct: 2520 LKPSDQTDNDQLQKELMF 2537 Score = 63.7 bits (148), Expect = 4e-08 Identities = 88/426 (20%), Positives = 185/426 (43%), Gaps = 31/426 (7%) Query: 1192 NQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQ 1251 N E +N S+L+Q N++N L+ + L + V+ E E + + AQ A Sbjct: 161 NLESLNDELSRLKQ-NSQNSELVKVLDNLTRTTDYVVNLENNENLERYTTYDAQLRA-IS 218 Query: 1252 KTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQE 1311 + L ++++ ++ ++L S QS Q ++ + S + +K + + E Sbjct: 219 QAALRLSTKVNSLNAELQELKHS-QSEMQIIVSQYKEVVPKISFHIETIEKLVSINDTDE 277 Query: 1312 KYADVI---NQIEILRSEIE---DEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQ 1365 + + +++ +RSE++ D ++ +Q + + Sbjct: 278 DDKNPLIFPQRLKRIRSEVQRLFDNNEKTNKELQKLKEQLELYENMKNGQSMKERQAELE 337 Query: 1366 SI-LNINEENAQLKK-SSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEY 1423 S+ L + ++NA+L++ + + E +V L +++ ++S+I K Sbjct: 338 SLRLELEKKNAELEQLKARYQSKQDPQLLAEIERIENEVQNLKNKIADRESQI--KALNL 395 Query: 1424 TITLTQRNDE-----FENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQK 1478 I Q +DE EN+ +++ + +K+IED K+ E+ +L+ K+ + E + Sbjct: 396 LIAQYQTDDEDKKEIIENLEKEIKDLKKQIED----KDKEIEVLKAKIAKIEEIPEDEED 451 Query: 1479 ESEI---ERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVT 1535 E + R + + N + E VSL QV +L + L+++ +M+ AL +++ EI Sbjct: 452 EDIVVAGTRDVDLGDFNEEEAEQVSLEDQVKQLKEKLDDKKKNGVQMKQALASKDAEIEK 511 Query: 1536 LNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDLAMYM 1595 LN++I L++ I++ + SD + DE K+L+D + DLA Sbjct: 512 LNEQIQELKDRNDKQEQNIEELNTKNSDLQNSNDEY------KKLIDELQNQLKDLAKNK 565 Query: 1596 LHQRDV 1601 D+ Sbjct: 566 AESSDL 571 Score = 63.3 bits (147), Expect = 5e-08 Identities = 282/1447 (19%), Positives = 589/1447 (40%), Gaps = 120/1447 (8%) Query: 212 EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271 ED K+ + + +A + D + D++S++ +L ++N LE E+ E Sbjct: 745 EDKKKLRIQQLKQLLASKQGEVDALKSQNDDLKSEN---ETLSKSNHELETKNKELEEEI 801 Query: 272 SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELT----KK 327 + E + + ++ E + + E SL + ++EL + Sbjct: 802 ENINNNKEGEVIDEKEASDVEVVCSTRDVDFEYENENDPETLKSLLKSKLSELENLQKEN 861 Query: 328 IELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWS 387 +L++ + +++ N+ L+ +L + E++++ +++ L + +S ++ ++ + Sbjct: 862 TDLMKQIE-ELKNENENLKRELENLKLENESLKRENER-LQLTADQSPQSKDKMIELLAN 919 Query: 388 QLSS-ETLNQDTDKKINK-NEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGK 445 Q++ E+L + +K N+ E+ K I+ N+ L + + + + + Sbjct: 920 QINQLESLVPELQQKTNEIEELKKENKQIKEENEKLKKENEDLKKSGSNKSSEEINQEEE 979 Query: 446 DTL--IAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIE 503 D I L+ +G E+ E+ K E L++E + K E Sbjct: 980 DLKKQIEDLKKALGYPQDGKEHKTPSELIEENEELKKKVEDLEKESGYPSDNKEHKSPSE 1039 Query: 504 KLKSAEEQITQLND--------EIDAANKNMIK-VKSNHKLKLKQ-MQKTIDNFSKVSDS 553 LK EE +++D E +K+ + +K N +LK + K + + Sbjct: 1040 LLKENEELKKKVDDLEKALGYPEDGKDHKSPSELIKENEELKKQNDALKRALGYPEDGKD 1099 Query: 554 NKEIVRLTEELHHLSQKVAELEEEKG---NLQLHLVDYDSGRMIESDVYKKMIEMENLAE 610 +K L +E L +KVA+LE+ G + Q H + R E++ KK + + + Sbjct: 1100 HKSPSELIQENEELKKKVADLEKALGYPADGQEHKTPSELLR--ENEELKKKLGISDSTT 1157 Query: 611 TR----LKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVH--L 664 K+ L S+ DL +++ L++ ED + + + E+K + L Sbjct: 1158 PSDNEDNKSPEELRSENKDLKKQIEDLKRALGYPEDGKEHKTPSELIKENEELKKQNDSL 1217 Query: 665 EEQIDALSASK-----KELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMD 719 ++ + K EL E+LK E L + E+ KE I+EN + Sbjct: 1218 KKALGYSEDGKDHKSPSELIKENEDLKKKVEDLEKALGFPEDGKEH--KTPSELIKENEE 1275 Query: 720 LTDKLEKMSAEKISELLAKINHEEQSKI-QTQFGIDAKIQERDLYIENIESEL------S 772 L ++ E + ++I +L + + E K +T + + +E EN++ +L S Sbjct: 1276 LKEETENIK-KQIEDLKRALGYPEDGKEHKTPSELINENEELKKQNENLKKKLGISGESS 1334 Query: 773 KYKSRICRLEESIAVME-DRRYSLERKADQLGSYLQEKQ-KAYSEYTIQEDELVN----- 825 KS + E I + + +E LG K+ K+ SE + +EL Sbjct: 1335 TDKSDSNKTPEEIKQENGELKKQIEDLKKALGYPEDGKEHKSPSELIKENEELKKQNDDL 1394 Query: 826 RLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANR 885 + A+ D K E+ EN+EL+KK I E + S +++ N L +K Sbjct: 1395 KRALGYPEDGKDHKTPSELIKENEELKKKLGISGESSTEESKSYEELKDLINDLKKKVE- 1453 Query: 886 TDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKV 945 DL ++ Y + +D +S + E+ L KK+ +DL+ + ++ K Sbjct: 1454 -DL--EKALGYPSDGKDHKSP-SELLKENDEL----KKQNDDLKKALGYPEDG--KEHKS 1503 Query: 946 LNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTE 1005 +E ++N E +L +E + + N + EEL N EL K ++ + + Y E Sbjct: 1504 PSELIKENEELKKKLGLS-EESSTDSKADNKSPEELKNENNEL-KKQIEALK-RVLGYPE 1560 Query: 1006 QYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQ 1065 NE + L+K+ +EE+ N + A + Y D++S ++ ++E +++E Sbjct: 1561 DG-NEHKTPSELIKE-NEELKKQNDNLKRA-LGYPEDGKDHKSP-SELIAEIEELKKEND 1616 Query: 1066 RVSKQL---LDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMS 1122 + + L D K H + L++E ++ KE + K + I S++ E + Sbjct: 1617 DLKRALGYPEDDKDHKSPSE-LIKENEELKKENDDLKK--RLGISGESSAEESNSPEELK 1673 Query: 1123 DDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLN 1182 ++ + + E I+E L++Q+ L L Y + + Sbjct: 1674 ---KQIEDLKKALGYPEDGKEHKTPSELIKENEELKKQNDALKRALG--YPEDGKDHKSP 1728 Query: 1183 TELTGHDVVNQEQINQLKSKLEQLNTENDN-----LLSTVAELRSSISSAVDQRGFEIAE 1237 +EL + ++++ L+ L D+ LL EL+ + + D+ E + Sbjct: 1729 SELIQENEELKKKVEDLEKALGYPQDGKDHKSPSELLKENEELKKKLGIS-DESSTEDNK 1787 Query: 1238 LWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQN 1297 + L +K L+ L E E S E+ K V+ + Sbjct: 1788 S-PEELKNENKYLKKQIEGLKKALGYPEDGKEHKSPSELIQENEDLKKKVS--DLEKALG 1844 Query: 1298 KLQDKEEHL--RNLQEKYADVINQIEILRSEIED--EKVAFXXXXXXXXXXXXXXXXDLR 1353 +D +EH L ++ ++ + + L+ E + +++ D Sbjct: 1845 YPEDGKEHKSPSELLKENEELKKENQRLKKENAELKKRLGIPVDQIIEGIMNESTASDES 1904 Query: 1354 TENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKD 1413 +N+S ++++ + I N+ ++ LK S N+ + L L+ Sbjct: 1905 EDNKSPEELKRE-IENLKKQLEDLKNSGSQENVDEEN-----NEMKEGADNLIDALQQSV 1958 Query: 1414 SEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESE-LAILRLKMHENANH 1472 E ++ + L +N E E ++ ++ ++IE++ E+++E + + + E N Sbjct: 1959 DEKNKQIDDLQQKLDDQNREIELLKAKV----EQIENINEEEDNEDIVVASTRDVELENV 2014 Query: 1473 YETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNE----MQTALEN 1528 E +E++ + I +L K+TE + Q+ + + + E++K NE +++ E+ Sbjct: 2015 EEESPEEAKERLAEQISQLQDKLTEKKKNSLQMKQALASKDAEISKLNEEIEQIKSEKED 2074 Query: 1529 QEIEIVTLNDEIT----NLQNMVRASSSK--IQKHVSFASDTKQGRDEQLD-NTMNKELL 1581 Q+ E+ LN+E+T L+N + SS + + F D ++ ++E+ + + N+ L Sbjct: 2075 QDKELEKLNNELTEALEKLENGKKKSSQEQNNENEEDFVDDIEKLKEERENLKSENESLK 2134 Query: 1582 DAVPRAE 1588 + P E Sbjct: 2135 NQAPENE 2141 Score = 55.6 bits (128), Expect = 1e-05 Identities = 108/533 (20%), Positives = 219/533 (41%), Gaps = 51/533 (9%) Query: 1076 QHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNV-DXXXXX 1134 Q N E+ L + +D + +L + I+S I P+ +++ D Sbjct: 88 QQNNEIDSLRAKYNDARAKSAAYELELQKAKQSLISRTINSNIHPLRSIGHDLEDEKESL 147 Query: 1135 XXXXXXXLKVQEE--EEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVN 1192 + + +E E E S L++ S N+EL K++ T T+ VVN Sbjct: 148 SDSISSTISIYDENLESLNDELSRLKQNSQ--NSEL----VKVLDNLTRTTDY----VVN 197 Query: 1193 QEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQK 1252 E LE+ T D L +++ +S+ V+ E+ EL +H +Q E Sbjct: 198 LEN----NENLERYTTY-DAQLRAISQAALRLSTKVNSLNAELQEL--KH-SQSEMQIIV 249 Query: 1253 TEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQ---DKEE----H 1305 ++++ V +F + + L S+ + +++ N ++ +++ +++++Q D E Sbjct: 250 SQYKEVVPKISFHIETIEKLVSINDTDEDDKNPLIFPQRLKRIRSEVQRLFDNNEKTNKE 309 Query: 1306 LRNLQEK---YADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQM 1362 L+ L+E+ Y ++ N + + E E + + + Q ++ Sbjct: 310 LQKLKEQLELYENMKNGQSMKERQAELESLRLELEKKNAELEQLKARYQSKQDPQLLAEI 369 Query: 1363 QE-----QSILN-INEENAQLKKSSXXXXXXXXXXXXR---VNDAEAKVLELTHQLELKD 1413 + Q++ N I + +Q+K + + + + E ++ +L Q+E KD Sbjct: 370 ERIENEVQNLKNKIADRESQIKALNLLIAQYQTDDEDKKEIIENLEKEIKDLKKQIEDKD 429 Query: 1414 SEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHY 1473 EI + + I + E E + +V R DL E E ++ + + Sbjct: 430 KEI--EVLKAKIAKIEEIPEDEE-DEDIVVAGTRDVDLGDFNEEEAE--QVSLEDQVKQL 484 Query: 1474 ETMQKESEIERVKLIEELNVKITESVSLNKQVAEL---NKALEEEVAKTNEMQTALENQE 1530 + + + V++ + L K E LN+Q+ EL N E+ + + N + L+N Sbjct: 485 KEKLDDKKKNGVQMKQALASKDAEIEKLNEQIQELKDRNDKQEQNIEELNTKNSDLQNSN 544 Query: 1531 IEIVTLNDEITN-LQNMVR--ASSSKIQKHVSFASDTKQGRDEQLDNTMNKEL 1580 E L DE+ N L+++ + A SS + + D+++ DE + NKEL Sbjct: 545 DEYKKLIDELQNQLKDLAKNKAESSDLNNSENTKQDSEKAEDENAETKSNKEL 597 >UniRef50_A2DDX5 Cluster: Viral A-type inclusion protein, putative; n=1; Trichomonas vaginalis G3|Rep: Viral A-type inclusion protein, putative - Trichomonas vaginalis G3 Length = 1794 Score = 196 bits (479), Expect = 3e-48 Identities = 288/1391 (20%), Positives = 596/1391 (42%), Gaps = 121/1391 (8%) Query: 234 DEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXX 293 D+ +L K++ KD +I+ L AN + E + + + ++ L Q E Sbjct: 258 DKISQLEKELAEKDDQINEL--ANLIEENDKKQGTQQNQNLNQNDEDAIQSLVTKYEEEI 315 Query: 294 XLAKQSIEPSCEEK-TEIEE-KGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLAT 351 K++ + E +I E K SL+ E++ + +L E + I QT+K+ E K+ Sbjct: 316 DDIKKNNQNEKENLINQINELKNSLK---NKEISSENDLNE-MKIIIEQTSKDYETKIQD 371 Query: 352 MGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINK--NEIAK 409 + T + S + S + +N S Q S++ + K+I+ E K Sbjct: 372 LMTNLEENSQKLNEMSQKLKESEEKNQKLNEMS-MLQASNDAEKEKFIKEISNLTKENEK 430 Query: 410 LEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQ-----LEHQQHMEGPS 464 L+ V+ K+ + E +++E L +++ ++ +Q+ + Sbjct: 431 LQTVLNENEKNRTENERLVAENQKLNSDLHEIGEVNKNLQTEIEKLTEIMKSEQNNKENE 490 Query: 465 LIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDE----ID 520 ++ + + E+ ++ +Q +L Q N E K+ +DL +KLK E + +LND+ I+ Sbjct: 491 MMSLLSQKEE--QVQALQVKLNQT-NQE-KEKQFEDLSQKLKQLEAEKQKLNDDYESKIN 546 Query: 521 AANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGN 580 +N + +N++ ++K+M +N + S +E + L E+ + +KV LEE+ Sbjct: 547 EIQQNDNETFTNYQNQIKEMMINNENLQNENKSLQEKISLNEKSDN--EKVLSLEEQLKE 604 Query: 581 LQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEV 640 + +S ++ + +ENL + + + L EL +Q + + Sbjct: 605 SK------NSISSLQEQLKSSQQTIENLEKNISEKSETYNEKIKSLTDELSTIQNTNENL 658 Query: 641 EDKLADISQ-LQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDL 699 ++++ + + L +++ K ++LEEQ L S+ E+ + E KL K Sbjct: 659 QNEIKSLQEKLSNNEKNDNEKILNLEEQ---LKNSQNEVRIGQE--KLSK---------F 704 Query: 700 ENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQE 759 EN+ + + +KL + +++ + + K+++ ++ L KI+ E+S + ++ ++ Sbjct: 705 ENEYDQMRSKL-SLMEKELSTSQKMKESLQKEKESLQEKISLSEKSDNEKVLSLEEQLNN 763 Query: 760 RDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQ 819 I N E + +S++ L E ++ + +LE K EK K+Y E Sbjct: 764 SKNMITNYEQNEKELQSQLSTLNEELSTSKKMIETLEEKISNNEKNGDEKVKSYEEQLNS 823 Query: 820 EDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNAL 879 +N L + + E+++ +E +NK+LQ+K I L E S SD ++ Y A Sbjct: 824 YRNTINELQQITQSN---EEKIKSLESQNKDLQEK--ISLSEK-----SESDKEKSYEAQ 873 Query: 880 VEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEF-NTQIE- 937 + N A++ + Q+ L+ + I + +I+++ I N Q E Sbjct: 874 LN--NLKQQAQNHISSLNQQIESLKQEISSIQQNDNETFTNYQNQIKEMMINNENLQNEV 931 Query: 938 SAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEEL-------------NKM 984 ++++K LNEK + E V LE QL KN I N N +EL +K Sbjct: 932 QSLQEKISLNEKSDN--EKVLSLEEQLNNSKNMITNYEQNEKELQSQLSTLNEELSTSKK 989 Query: 985 NLELIDKHV---QKQQTQSPDYTEQYI----NEINKLNALLKQKDEEIIALNQKINNAQV 1037 +E +++ + +K + E+ + N I+ L LK + I L + I+ Sbjct: 990 MIETLEEKISNNEKSDNEKVLSLEEQLKESKNSISSLQEQLKSSQQTIENLEKNISEKSE 1049 Query: 1038 SYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKE 1097 +Y + +L+ K EN++ E++ + ++L ++++++ E L EQ + +K+ + Sbjct: 1050 TYNEKIKSLTDELSTIQNKNENLQNEIKSLQEKLSNNEKNDNEKVKLYEEQLNSLKKEND 1109 Query: 1098 TKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVL 1157 +I K++ + + + N++ + + E+ + + S Sbjct: 1110 NLKQEMSDIQKSDNETFENYQNQIKEMMQNLEEAENKVSTLQEQISMNEKSDSEKVTSY- 1168 Query: 1158 QEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTV 1217 + + A+++ E +E K + + + +E+IN L ++ + E + Sbjct: 1169 EAKIAQMHQEKKELEKKFTAAKQIVSNNRQEKKEMEEKINSLTKQVSDKDEELQKSKEEI 1228 Query: 1218 AELRSSISSAVDQRGFEIAELWKQHLAQREADFQK-TEHELRVQLSAFESK-YEQLLDSV 1275 L ++S ++ ++AE +Q L++ E+ QK TE E VQ ++K E L + Sbjct: 1229 ESLNHKVTSNEAEKQ-KVAEDLQQKLSEIESLKQKLTEKENDVQKVTEQNKSIEDLKQQI 1287 Query: 1276 QSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFX 1335 + T+ T+E ++ +L+ K++ EK ++I L ++E K Sbjct: 1288 SEKEKVITDNQKTIENLSFELTELKQKKDD----SEKDKEIIQN---LTKDLEKMKADLD 1340 Query: 1336 XXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRV 1395 ++ Q+ + E + + ++EEN +L K +V Sbjct: 1341 SKQKENDEIRSRLNREIEDNKQALAKAVETAKI-LSEENEKLTKQME-----------QV 1388 Query: 1396 NDAEAKVLE-LTHQLELKDSEIYQKTHEYTITLTQRN---DEFENVRQQLVEYEKRIEDL 1451 + +E + + L+ ++ +S + T L RN E +L E + + + Sbjct: 1389 SSSETEKCQVLSSKISTLESRLQSSETRATSVLEDRNRLSSELLRTMSELKESKNEKDKI 1448 Query: 1452 TYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAEL--- 1508 T E ++ L E +YE K E E+ L ++N + +L K V L Sbjct: 1449 TQEFNDKIKELESNSREQTANYEGKIKLLESEKSSLETKINEDQLKISNLEKNVQNLSNK 1508 Query: 1509 NKALEEEVAKTNEMQTALENQ----EIEIVTL---NDEITNLQNMVRASSSKIQKHVSFA 1561 N + EV+K E + L+NQ E+EI+ + ND +T+ +R S +K+Q++V+ Sbjct: 1509 NSVSDNEVSKLKEDNSKLKNQISNFEVEIMQIKESNDLLTSQNEKLRESKNKLQQNVNDL 1568 Query: 1562 SDTKQGRDEQL 1572 TK+ +++ Sbjct: 1569 EATKKDLTQKM 1579 Score = 193 bits (470), Expect = 4e-47 Identities = 280/1426 (19%), Positives = 599/1426 (42%), Gaps = 102/1426 (7%) Query: 149 NTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXX 208 N EK+N ++ + ++ + + +NE IIE +K Sbjct: 321 NNQNEKENLINQINELKNSLKNKEISSENDLNEMKIIIEQTSKDYETKIQDLMTNLEENS 380 Query: 209 XXXEDTKQQMTKMQE-----NFIAM-EAEWKDEKQRLLKDIES---KDVRISSLEEANKL 259 + Q++ + +E N ++M +A EK++ +K+I + ++ ++ ++ N+ Sbjct: 381 QKLNEMSQKLKESEEKNQKLNEMSMLQASNDAEKEKFIKEISNLTKENEKLQTVLNENEK 440 Query: 260 LEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEI--EEKGSLE 317 + E+ KL +L + ++++ E+ TEI E+ + E Sbjct: 441 NRTENERLVAENQKLNSDLHEIGE------------VNKNLQTEIEKLTEIMKSEQNNKE 488 Query: 318 IANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSG-- 375 M+ L++K E ++ L ++ QTN+E E + + + K + + +K + K Sbjct: 489 NEMMSLLSQKEEQVQALQVKLNQTNQEKEKQFEDLSQKLKQLEAEKQKLNDDYESKINEI 548 Query: 376 -RNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTX 434 +N + +Q+ +N + + NK+ K+ + +S N+ ++ E + E Sbjct: 549 QQNDNETFTNYQNQIKEMMINNENLQNENKSLQEKISLNEKSDNEKVLSLEEQLKESKNS 608 Query: 435 XXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELND--E 492 I L+ + E + + + T++++ I E L+ E+ E Sbjct: 609 ISSLQEQLKSSQQTIENLEKNISEKSETYNE-KIKSLTDELSTIQNTNENLQNEIKSLQE 667 Query: 493 IKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNH---KLKLKQMQKTIDNFSK 549 N K+ EK+ + EEQ+ +E+ + + K ++ + + KL M+K + K Sbjct: 668 KLSNNEKNDNEKILNLEEQLKNSQNEVRIGQEKLSKFENEYDQMRSKLSLMEKELSTSQK 727 Query: 550 VSDS-NKEIVRLTEELHHL----SQKVAELEEEKGNLQLHLVDYDSG-RMIESDVY---K 600 + +S KE L E++ ++KV LEE+ N + + +Y+ + ++S + + Sbjct: 728 MKESLQKEKESLQEKISLSEKSDNEKVLSLEEQLNNSKNMITNYEQNEKELQSQLSTLNE 787 Query: 601 KMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCS-EI 659 ++ + + ET + IS E + V+ Y ++L I+Q +++ S E Sbjct: 788 ELSTSKKMIETLEEKISNNEKNGDEKVKSYEEQLNSYRNTINELQQITQSNEEKIKSLES 847 Query: 660 KSVHLEEQIDALSASK----KELALVIENLKLDKEQLYGTI-KDLENDKEDIMNKLQNYI 714 ++ L+E+I S+ K + NLK + ++ + +E+ K++I + QN Sbjct: 848 QNKDLQEKISLSEKSESDKEKSYEAQLNNLKQQAQNHISSLNQQIESLKQEISSIQQNDN 907 Query: 715 QENMDLTDKLEKMSAE------KISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIE 768 + + +++++M ++ L KI+ E+S + ++ ++ I N E Sbjct: 908 ETFTNYQNQIKEMMINNENLQNEVQSLQEKISLNEKSDNEKVLSLEEQLNNSKNMITNYE 967 Query: 769 SELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLA 828 + +S++ L E ++ + +LE K EK + E + ++ L Sbjct: 968 QNEKELQSQLSTLNEELSTSKKMIETLEEKISNNEKSDNEKVLSLEEQLKESKNSISSLQ 1027 Query: 829 V-LMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTD 887 L + +E I +++ +K + L +E +Q ++Q +L EK + + Sbjct: 1028 EQLKSSQQTIENLEKNISEKSETYNEKIKSLTDELSTIQNKNENLQNEIKSLQEKLSNNE 1087 Query: 888 LAESESTK-YQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVL 946 ++E K Y+ QL L+ + E + +K + E E + QI+ +++ + Sbjct: 1088 KNDNEKVKLYEEQLNSLKKENDNLKQEMSDI---QKSDNETFE-NYQNQIKEMMQNLEEA 1143 Query: 947 NEKYEKNIEYVTQLEAQLQE----YKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPD 1002 K E ++ E E Y+ I ++ +EL K K + Q Sbjct: 1144 ENKVSTLQEQISMNEKSDSEKVTSYEAKIAQMHQEKKELEKKFTAA--KQIVSNNRQEKK 1201 Query: 1003 YTEQYINEINKL----NALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTT--- 1055 E+ IN + K + L++ EEI +LN K+ + + + D + KL++ + Sbjct: 1202 EMEEKINSLTKQVSDKDEELQKSKEEIESLNHKVTSNEAEKQKVAEDLQQKLSEIESLKQ 1261 Query: 1056 KLENMEEEMQRVSKQ---LLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGM 1112 KL E ++Q+V++Q + D KQ E + ++ + I+ L +LT E+ K + Sbjct: 1262 KLTEKENDVQKVTEQNKSIEDLKQQISEKEKVITDNQKTIENLS-FELT-ELKQKKDDSE 1319 Query: 1113 IISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQE--QSAKLNTELQE 1170 I+ ++ D + ++ + E + L + ++AK+ +E E Sbjct: 1320 KDKEIIQNLTKDLEKMKADLDSKQKENDEIRSRLNREIEDNKQALAKAVETAKILSEENE 1379 Query: 1171 CYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQ 1230 TK Q+E +++ T V +I+ L+S+L+ T ++L L S + + + Sbjct: 1380 KLTK--QMEQVSSSETEKCQVLSSKISTLESRLQSSETRATSVLEDRNRLSSELLRTMSE 1437 Query: 1231 RGFEIAELWKQHLAQREAD-FQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETN----K 1285 + ++ K + Q D ++ E R Q + +E K + LL+S +SS + + N K Sbjct: 1438 --LKESKNEKDKITQEFNDKIKELESNSREQTANYEGKIK-LLESEKSSLETKINEDQLK 1494 Query: 1286 IVTMEQ-VTSLQNKLQDKEEHLRNLQEKYADVINQI-----EILR-SEIEDEKVAFXXXX 1338 I +E+ V +L NK + + L+E + + NQI EI++ E D + Sbjct: 1495 ISNLEKNVQNLSNKNSVSDNEVSKLKEDNSKLKNQISNFEVEIMQIKESNDLLTSQNEKL 1554 Query: 1339 XXXXXXXXXXXXDLRTENQSYKQMQEQSILNINE-ENAQLKKSSXXXXXXXXXXXXRVND 1397 DL + Q Q + E E L ++ ++ Sbjct: 1555 RESKNKLQQNVNDLEATKKDLTQKMAQMKCDSRENEINSLLETKKSLEEKISVLQNQIAT 1614 Query: 1398 AEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKES 1457 +L Q+ELK+ +I + +Y ++Q ++ +R++ +E E +I+++ Y+ E Sbjct: 1615 ILKDKSDLAEQIELKEIDIKDQMLKYKEQMSQNDNVVFEMRKEKIELENQIKEIKYQNEL 1674 Query: 1458 ELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNK 1503 ++ + + E YE E + K +++L+ K+ + VS N+ Sbjct: 1675 NVSKMNQEKEELTKSYE----EKILLYAKKVQQLSRKL-QKVSENQ 1715 Score = 180 bits (438), Expect = 3e-43 Identities = 248/1280 (19%), Positives = 568/1280 (44%), Gaps = 113/1280 (8%) Query: 337 QIRQTNKELENKLATMGTESKAVS--SPSKKGSPLISRKSGRNTASKMKSP-WSQLSSET 393 ++ + N+ L+ +LA+ +S+ + S ++ S + +N+ M + + Sbjct: 187 ELMRENESLKEQLASKPAQSQDLLDFSSNQNNSNFNQSSNQQNSQQNMLLDLFGEQQPAN 246 Query: 394 LNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGK--DTLIAQ 451 +Q+TD + ++I++LE + + + + +I E D + + I Sbjct: 247 QSQNTDIQRLNDKISQLEKELAEKDDQINELANLIEENDKKQGTQQNQNLNQNDEDAIQS 306 Query: 452 LQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVN-VKDLIEKL-KSAE 509 L ++++ ++ + +N+I +++ LK + D+N +K +IE+ K E Sbjct: 307 LVTKYEEEIDDIKKNNQNEKENLINQINELKNSLKNKEISSENDLNEMKIIIEQTSKDYE 366 Query: 510 EQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSN--------KEIVRLT 561 +I L ++ ++ + ++ K ++ QK ++ S + SN KEI LT Sbjct: 367 TKIQDLMTNLEENSQKLNEMSQKLKESEEKNQK-LNEMSMLQASNDAEKEKFIKEISNLT 425 Query: 562 EELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLES 621 +E L + E E+ + + + + + + SD+++ +NL K +++S Sbjct: 426 KENEKLQTVLNENEKNRTENERLVAE---NQKLNSDLHEIGEVNKNLQTEIEKLTEIMKS 482 Query: 622 QKFDLVQEL-HILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELAL 680 ++ + E+ +L QK ++V+ ++Q ++ E + L +++ L A K++L Sbjct: 483 EQNNKENEMMSLLSQKEEQVQALQVKLNQTNQEK---EKQFEDLSQKLKQLEAEKQKLND 539 Query: 681 VIENLKLDKEQLYG--TIKDLENDKEDIMNKLQNYIQENMDLTDKL---EKMSAEKISEL 735 E+ K+++ Q T + +N +++M +N EN L +K+ EK EK+ L Sbjct: 540 DYES-KINEIQQNDNETFTNYQNQIKEMMINNENLQNENKSLQEKISLNEKSDNEKVLSL 598 Query: 736 LAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSL 795 ++ + S Q + + Q + +NI + Y +I L + ++ +++ +L Sbjct: 599 EEQLKESKNSISSLQEQLKSSQQTIENLEKNISEKSETYNEKIKSLTDELSTIQNTNENL 658 Query: 796 ERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKN 855 + + L L +K +E + +E +L + R+ +++L + E+E +++ K Sbjct: 659 QNEIKSLQEKLSNNEKNDNEKILNLEE---QLKNSQNEVRIGQEKLSKFENEYDQMRSKL 715 Query: 856 QILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQ 915 ++ +E Q +Q+ +L EK + ++ +++E L + +N K + ++ Sbjct: 716 SLMEKELSTSQKMKESLQKEKESLQEKISLSEKSDNEKV---LSLEEQLNNSKNMITNYE 772 Query: 916 TLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKY---EKN-IEYVTQLEAQLQEYKNNI 971 Q +KE++ N ++ ++ + + L EK EKN E V E QL Y+N I Sbjct: 773 ----QNEKELQSQLSTLNEELSTSKKMIETLEEKISNNEKNGDEKVKSYEEQLNSYRNTI 828 Query: 972 ENLNM-------NVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNAL----LKQ 1020 L ++ L N +L +K ++++S D + Y ++N L + Sbjct: 829 NELQQITQSNEEKIKSLESQNKDLQEKISLSEKSES-DKEKSYEAQLNNLKQQAQNHISS 887 Query: 1021 KDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQL-LDSKQHNE 1079 +++I +L Q+I++ Q + ++Y++++ + EN++ E+Q + +++ L+ K NE Sbjct: 888 LNQQIESLKQEISSIQQNDNETFTNYQNQIKEMMINNENLQNEVQSLQEKISLNEKSDNE 947 Query: 1080 ELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXX 1139 ++ L ++Q+ K +E N + + +S+ E +S ++ Sbjct: 948 KVLSL----EEQLNNSKNMITNYEQNEKELQSQ-LSTLNEELSTSKKMIETLEEKISNN- 1001 Query: 1140 XXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQL 1199 + + E+ + L+E +++ ++ + +E L ++ E+I L Sbjct: 1002 ---EKSDNEKVLSLEEQLKESKNSISSLQEQLKSSQQTIENLEKNISEKSETYNEKIKSL 1058 Query: 1200 KSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELR- 1258 +L + +N+NL + + L+ +S+ ++ E +L+++ L + + + E+ Sbjct: 1059 TDELSTIQNKNENLQNEIKSLQEKLSNN-EKNDNEKVKLYEEQLNSLKKENDNLKQEMSD 1117 Query: 1259 VQLSAFES--KYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADV 1316 +Q S E+ Y+ + + + +E NK+ T+++ S+ N+ D E+ Y Sbjct: 1118 IQKSDNETFENYQNQIKEMMQNLEEAENKVSTLQEQISM-NEKSDSEK-----VTSYEAK 1171 Query: 1317 INQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQ 1376 I Q+ + E+E + A + + N+ K+ E+ I ++ ++ + Sbjct: 1172 IAQMHQEKKELEKKFTA---------------AKQIVSNNRQEKKEMEEKINSLTKQVSD 1216 Query: 1377 LKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYT------ITLTQR 1430 + +V EA+ ++ L+ K SEI + T +T++ Sbjct: 1217 KDEELQKSKEEIESLNHKVTSNEAEKQKVAEDLQQKLSEIESLKQKLTEKENDVQKVTEQ 1276 Query: 1431 NDEFENVRQQLVEYEKRIED--LTYEKES-ELAILRLKMHENANHYETMQK-ESEIERVK 1486 N E+++QQ+ E EK I D T E S EL L+ K ++ E +Q ++E++K Sbjct: 1277 NKSIEDLKQQISEKEKVITDNQKTIENLSFELTELKQKKDDSEKDKEIIQNLTKDLEKMK 1336 Query: 1487 L--------IEELNVKITESVSLNKQ----VAELNKALEEEVAK-TNEMQTALENQEIEI 1533 +E+ ++ + NKQ E K L EE K T +M+ ++ + Sbjct: 1337 ADLDSKQKENDEIRSRLNREIEDNKQALAKAVETAKILSEENEKLTKQMEQVSSSETEKC 1396 Query: 1534 VTLNDEITNLQNMVRASSSK 1553 L+ +I+ L++ +++S ++ Sbjct: 1397 QVLSSKISTLESRLQSSETR 1416 Score = 171 bits (417), Expect = 1e-40 Identities = 254/1248 (20%), Positives = 550/1248 (44%), Gaps = 114/1248 (9%) Query: 387 SQLSSETLNQDTDKKIN--KN-----EIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXX 439 S+L+ +TL+Q+ +I KN EI KL ++ NK+ + E IS+ + Sbjct: 83 SELAEKTLSQEKSLEIEYAKNKRFAQEILKLRSQLEKQNKE--NDEAKISDNEAINELIA 140 Query: 440 XXXXGKDTLIAQLQ-LEHQQHMEGPSLIHVGTNTEDV--------NEIAKVQEQLKQELN 490 + L+++++ LE QQ M P + +D+ +E+ + E LK++L Sbjct: 141 EFNKERRELLSKIEELEKQQRMNSPDAEQISKPKDDIVDDFLQRIDELMRENESLKEQLA 200 Query: 491 DEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKT-IDNFS- 548 K +DL++ + + + +NM+ + Q Q T I + Sbjct: 201 S--KPAQSQDLLDFSSNQNNSNFNQSSNQQNSQQNMLLDLFGEQQPANQSQNTDIQRLND 258 Query: 549 KVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENL 608 K+S KE+ ++++ L+ + E ++++G Q ++ + I+S V K E++++ Sbjct: 259 KISQLEKELAEKDDQINELANLIEENDKKQGTQQNQNLNQNDEDAIQSLVTKYEEEIDDI 318 Query: 609 AETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSV--HLEE 666 + L +Q +L L + + +++ I + S ++I+ + +LEE Sbjct: 319 KKNNQNEKENLINQINELKNSLKNKEISSENDLNEMKIIIEQTSKDYETKIQDLMTNLEE 378 Query: 667 QIDALSASKKELALVIE-NLKLDKEQLYGTIKDLENDK--EDIMN------KLQNYIQEN 717 L+ ++L E N KL++ + D E +K ++I N KLQ + EN Sbjct: 379 NSQKLNEMSQKLKESEEKNQKLNEMSMLQASNDAEKEKFIKEISNLTKENEKLQTVLNEN 438 Query: 718 MDLTDKLEKMSAE--KISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIE--SELSK 773 + E++ AE K++ L +I E +QT+ +I + + + E S LS+ Sbjct: 439 EKNRTENERLVAENQKLNSDLHEIG-EVNKNLQTEIEKLTEIMKSEQNNKENEMMSLLSQ 497 Query: 774 YKSRICRLEESI-AVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELV-NRLAVLM 831 + ++ L+ + +++ E + +L EKQK +Y + +E+ N Sbjct: 498 KEEQVQALQVKLNQTNQEKEKQFEDLSQKLKQLEAEKQKLNDDYESKINEIQQNDNETFT 557 Query: 832 DHDRVVEKQLLE---IEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDL 888 ++ +++ ++ +++ENK LQ+K I L E + + LS +Q L E N Sbjct: 558 NYQNQIKEMMINNENLQNENKSLQEK--ISLNEKSDNEKVLSLEEQ----LKESKNSISS 611 Query: 889 AESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNE 948 + + Q + +LE N+ + + I E+ ++ N +++ I+ + Sbjct: 612 LQEQLKSSQQTIENLEKNISEKSETYNEKIKSLTDELSTIQ-NTNENLQNEIKSLQEKLS 670 Query: 949 KYEKNI-EYVTQLEAQLQEYKNNI----ENLNMNVEELNKMN--LELIDKHVQKQQTQSP 1001 EKN E + LE QL+ +N + E L+ E ++M L L++K + Q Sbjct: 671 NNEKNDNEKILNLEEQLKNSQNEVRIGQEKLSKFENEYDQMRSKLSLMEKELSTSQKMKE 730 Query: 1002 DYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENME 1061 ++ + K++ K +E++++L +++NN++ +M+++YE + ++L + Sbjct: 731 SLQKEKESLQEKISLSEKSDNEKVLSLEEQLNNSK----NMITNYEQNEKELQSQLSTLN 786 Query: 1062 EEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPM 1121 EE+ SK+++++ + E++ + D+++K +E ++ I + + + S+ + Sbjct: 787 EELS-TSKKMIETLE--EKISNNEKNGDEKVKSYEEQLNSYRNTINELQQITQSNEEKIK 843 Query: 1122 SDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQ-LET 1180 S ++ N D + + E+ E +E+S + Q L + Q + + Q +E+ Sbjct: 844 SLESQNKDLQEK--------ISLSEKSESDKEKSY-EAQLNNLKQQAQNHISSLNQQIES 894 Query: 1181 LNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWK 1240 L E++ + E +++++++ N+NL + V L+ IS ++ L + Sbjct: 895 LKQEISSIQQNDNETFTNYQNQIKEMMINNENLQNEVQSLQEKISLNEKSDNEKVLSLEE 954 Query: 1241 QHLAQRE--ADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQE-ETNKIVTMEQVTSLQN 1297 Q + ++++ E EL+ QLS + +++ ++ N+ E+V SL+ Sbjct: 955 QLNNSKNMITNYEQNEKELQSQLSTLNEELSTSKKMIETLEEKISNNEKSDNEKVLSLEE 1014 Query: 1298 KLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQ 1357 +L++ + + +LQE+ IE L I ++ T N+ Sbjct: 1015 QLKESKNSISSLQEQLKSSQQTIENLEKNISEKS---------------------ETYNE 1053 Query: 1358 SYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIY 1417 K + ++ + I +N L+ ND E KV QL E Sbjct: 1054 KIKSLTDE-LSTIQNKNENLQNE--IKSLQEKLSNNEKNDNE-KVKLYEEQLNSLKKEND 1109 Query: 1418 QKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILR--LKMHENANHYET 1475 E + N+ FEN + Q+ E + +E E E++++ L+ + M+E ++ + Sbjct: 1110 NLKQEMSDIQKSDNETFENYQNQIKEMMQNLE----EAENKVSTLQEQISMNEKSDSEKV 1165 Query: 1476 MQKESEIERV-KLIEELNVKITESVSLNKQVAELNKALEEEV----AKTNEMQTALENQE 1530 E++I ++ + +EL K T + + + K +EE++ + ++ L+ + Sbjct: 1166 TSYEAKIAQMHQEKKELEKKFTAAKQIVSNNRQEKKEMEEKINSLTKQVSDKDEELQKSK 1225 Query: 1531 IEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNK 1578 EI +LN ++T+ + + + +Q+ +S KQ E+ +N + K Sbjct: 1226 EEIESLNHKVTSNEAEKQKVAEDLQQKLSEIESLKQKLTEK-ENDVQK 1272 Score = 157 bits (380), Expect = 3e-36 Identities = 235/1195 (19%), Positives = 524/1195 (43%), Gaps = 103/1195 (8%) Query: 144 VTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXX 203 V L +KE N++S LQ ++K + TI +L++ I+EK + K K+ T Sbjct: 595 VLSLEEQLKESKNSISSLQEQLKSSQQTIENLEKNISEKSETYNEKIKSLT-------DE 647 Query: 204 XXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAA 263 E+ + ++ +QE E K++ +++L ++E + ++ S E + + Sbjct: 648 LSTIQNTNENLQNEIKSLQEKLSNNE---KNDNEKIL-NLE-EQLKNSQNEVRIGQEKLS 702 Query: 264 RFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTE 323 +FE E+ ++ +L L K+ + S +EK + EK E + Sbjct: 703 KFE--NEYDQMRSKLSLMEKELSTSQKMKESLQKE--KESLQEKISLSEKSDNE--KVLS 756 Query: 324 LTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRK---SGRNTAS 380 L +++ +++ Q KEL+++L+T+ E S SKK + K + +N Sbjct: 757 LEEQLNNSKNMITNYEQNEKELQSQLSTLNEE----LSTSKKMIETLEEKISNNEKNGDE 812 Query: 381 KMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXX 440 K+KS QL+S + ++I ++ K++ ++S NKDL +K + + ++ Sbjct: 813 KVKSYEEQLNSYRNTINELQQITQSNEEKIKS-LESQNKDLQEKISLSEKSESDKEKSYE 871 Query: 441 XXXGKDTLIAQLQLEH-QQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQ-ELNDEIKDVNV 498 AQ + Q +E D Q Q+K+ +N+E V Sbjct: 872 AQLNNLKQQAQNHISSLNQQIESLKQEISSIQQNDNETFTNYQNQIKEMMINNENLQNEV 931 Query: 499 KDLIEKL----KSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSN 554 + L EK+ KS E++ L ++++ +KNMI +N++ K++Q + ++ ++ Sbjct: 932 QSLQEKISLNEKSDNEKVLSLEEQLN-NSKNMI---TNYEQNEKELQSQLSTLNEELSTS 987 Query: 555 KEIVRLTEELHHLSQKVAELEEEKGNLQLHLVD-YDSGRMIESDVYKKMIEMENLAETRL 613 K+++ EE +S E+ +L+ L + +S ++ + +ENL + Sbjct: 988 KKMIETLEE--KISNNEKSDNEKVLSLEEQLKESKNSISSLQEQLKSSQQTIENLEKNIS 1045 Query: 614 KAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHL-EEQIDALS 672 + + L EL +Q K + +++++ + + S+ ++ + V L EEQ+++L Sbjct: 1046 EKSETYNEKIKSLTDELSTIQNKNENLQNEIKSLQEKLSNNEKNDNEKVKLYEEQLNSLK 1105 Query: 673 ASKKELALVIENL-KLDK---EQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMS 728 L + ++ K D E IK++ + E+ NK+ +QE + + EK Sbjct: 1106 KENDNLKQEMSDIQKSDNETFENYQNQIKEMMQNLEEAENKVST-LQEQISMN---EKSD 1161 Query: 729 AEKISELLAKI--NHEEQSKIQTQFGIDAKIQERDLY-IENIESELSKYKSRICRLEESI 785 +EK++ AKI H+E+ +++ +F +I + + +E +++ ++ +E + Sbjct: 1162 SEKVTSYEAKIAQMHQEKKELEKKFTAAKQIVSNNRQEKKEMEEKINSLTKQVSDKDEEL 1221 Query: 786 AVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIE 845 ++ SL K + S EKQK + + E+ + L + + V+K + Sbjct: 1222 QKSKEEIESLNHK---VTSNEAEKQKVAEDLQQKLSEIESLKQKLTEKENDVQK----VT 1274 Query: 846 HENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLE- 904 +NK ++ Q + E+ + + + ++ L E + D +E + Q +DLE Sbjct: 1275 EQNKSIEDLKQQISEKEKVITDNQKTIENLSFELTELKQKKDDSEKDKEIIQNLTKDLEK 1334 Query: 905 --SNLKRITHEHQTLIVQKKKEIEDLEIEFNTQ-IESAIRDKKVLNEKYEKNIEYVTQLE 961 ++L E+ + + +EIED N Q + A+ K+L+E+ EK + + Q+ Sbjct: 1335 MKADLDSKQKENDEIRSRLNREIED-----NKQALAKAVETAKILSEENEKLTKQMEQVS 1389 Query: 962 AQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQK 1021 + E K + + ++ E + E V + + + + + + +++L +K Sbjct: 1390 SSETE-KCQVLSSKISTLESRLQSSETRATSVLEDRNR---LSSELLRTMSELKESKNEK 1445 Query: 1022 DEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEEL 1081 D+ N KI + + ++YE K+ ++ ++E ++ ++ + +++ + L Sbjct: 1446 DKITQEFNDKIKELESNSREQTANYEGKIKLLESEKSSLETKINEDQLKISNLEKNVQNL 1505 Query: 1082 QILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXX 1141 D+++ +LKE K + I + +E M +N Sbjct: 1506 SNKNSVSDNEVSKLKEDN-------SKLKNQISNFEVEIMQIKESN-------------D 1545 Query: 1142 LKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKS 1201 L + E+ + ++ LQ+ L ++ K+ Q++ + E + +N + + K Sbjct: 1546 LLTSQNEKLRESKNKLQQNVNDLEATKKDLTQKMAQMKCDSRE----NEIN--SLLETKK 1599 Query: 1202 KLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAE---LWKQHLAQRE-ADFQKTEHEL 1257 LE+ + N ++T+ + +S ++ ++ + +I + +K+ ++Q + F+ + ++ Sbjct: 1600 SLEEKISVLQNQIATILKDKSDLAEQIELKEIDIKDQMLKYKEQMSQNDNVVFEMRKEKI 1659 Query: 1258 RVQLSAFESKYEQLLD-SVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQE 1311 ++ E KY+ L+ S + +EE K E++ K+Q L+ + E Sbjct: 1660 ELENQIKEIKYQNELNVSKMNQEKEELTKSYE-EKILLYAKKVQQLSRKLQKVSE 1713 Score = 135 bits (326), Expect = 1e-29 Identities = 227/1044 (21%), Positives = 439/1044 (42%), Gaps = 91/1044 (8%) Query: 97 TLKQKEI-LMEKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGD----VTHLSNTI 151 +L +KE+ +K+K+ + K S + QL + +T+ Sbjct: 716 SLMEKELSTSQKMKESLQKEKESLQEKISLSEKSDNEKVLSLEEQLNNSKNMITNYEQNE 775 Query: 152 KEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXX 211 KE + LS L ++ + I L+EKI+ ++ + K K+ Sbjct: 776 KELQSQLSTLNEELSTSKKMIETLEEKISNNEKNGDEKVKSYEEQLNSYRNTI------- 828 Query: 212 EDTKQQMTKMQENFI-AMEAEWKDEKQRLLKDIESKDVRISSLE-EANKLLEAARFEISL 269 + QQ+T+ E I ++E++ KD ++++ +S+ + S E + N L + A+ IS Sbjct: 829 -NELQQITQSNEEKIKSLESQNKDLQEKISLSEKSESDKEKSYEAQLNNLKQQAQNHISS 887 Query: 270 EHSK---LAQELEQXXXXXXXXXXXXXXLAKQSI---EPSCEEKTEIEEKGSLEIANMTE 323 + + L QE+ K+ + E E ++EK SL + E Sbjct: 888 LNQQIESLKQEISSIQQNDNETFTNYQNQIKEMMINNENLQNEVQSLQEKISLNEKSDNE 947 Query: 324 LTKKIELLEHLN------CQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRN 377 K + L E LN Q KEL+++L+T+ E S SKK + K N Sbjct: 948 --KVLSLEEQLNNSKNMITNYEQNEKELQSQLSTLNEEL----STSKKMIETLEEKISNN 1001 Query: 378 TASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXX 437 S + S L + + ++ + I++L K++ +K +EK Sbjct: 1002 EKSDNEKVLS-LEEQLKESKNSISSLQEQLKSSQQTIENLEKNISEKSETYNEKIKSLTD 1060 Query: 438 XXXXXXGKD----TLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEI 493 K+ I LQ E + E V E +N + K + LKQE++D Sbjct: 1061 ELSTIQNKNENLQNEIKSLQ-EKLSNNEKNDNEKVKLYEEQLNSLKKENDNLKQEMSDIQ 1119 Query: 494 KDVN---------VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTI 544 K N +K++++ L+ AE +++ L ++I K+ + ++++ K+ QM + Sbjct: 1120 KSDNETFENYQNQIKEMMQNLEEAENKVSTLQEQISMNEKSDSEKVTSYEAKIAQMHQEK 1179 Query: 545 DNFSK--------VSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIES 596 K VS++ +E + E+++ L+++V++ +EE LQ + +S + Sbjct: 1180 KELEKKFTAAKQIVSNNRQEKKEMEEKINSLTKQVSDKDEE---LQKSKEEIES---LNH 1233 Query: 597 DVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVC 656 V E + +AE + +S +ES K L ++ + +Q K E + D+ Q S++ Sbjct: 1234 KVTSNEAEKQKVAEDLQQKLSEIESLKQKLTEKENDVQ-KVTEQNKSIEDLKQQISEK-- 1290 Query: 657 SEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQE 716 E ++ I+ LS EL ++ + DKE + KDLE K D+ +K + + Sbjct: 1291 -EKVITDNQKTIENLSFELTELKQKKDDSEKDKEIIQNLTKDLEKMKADLDSKQKENDEI 1349 Query: 717 NMDLTDKLE--KMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKY 774 L ++E K + K E AKI EE K+ Q + + + + S++S Sbjct: 1350 RSRLNREIEDNKQALAKAVET-AKILSEENEKLTKQMEQVSSSETEKCQV--LSSKISTL 1406 Query: 775 KSRICRLE-ESIAVMEDR-RYSLE--RKADQLGSYLQEKQKAYSEYTIQEDELVN----R 826 +SR+ E + +V+EDR R S E R +L EK K E+ + EL + + Sbjct: 1407 ESRLQSSETRATSVLEDRNRLSSELLRTMSELKESKNEKDKITQEFNDKIKELESNSREQ 1466 Query: 827 LAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRT 886 A +++E + +E + E Q K L + QNL S + L E ++ Sbjct: 1467 TANYEGKIKLLESEKSSLETKINEDQLKISNLEKNVQNLSNKNSVSDNEVSKLKEDNSKL 1526 Query: 887 DLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKK---EIEDLEIEFNTQIESAIRDK 943 +++ + ++ ++ ++ + +T +++ L K K + DLE + + Sbjct: 1527 ---KNQISNFEVEIMQIKESNDLLTSQNEKLRESKNKLQQNVNDLEAT-KKDLTQKMAQM 1582 Query: 944 KVLNEKYEKN--IEYVTQLEAQLQEYKNNIENLNMNVEEL-NKMNLELID-KHVQKQQTQ 999 K + + E N +E LE ++ +N I + + +L ++ L+ ID K + + Sbjct: 1583 KCDSRENEINSLLETKKSLEEKISVLQNQIATILKDKSDLAEQIELKEIDIKDQMLKYKE 1642 Query: 1000 SPDYTEQYINEINKLNALLKQKDEEIIALNQ-KINNAQVSYMSMVSDYESKLAQFTTKLE 1058 + + E+ K L+ + +EI N+ ++ + YE K+ + K++ Sbjct: 1643 QMSQNDNVVFEMRKEKIELENQIKEIKYQNELNVSKMNQEKEELTKSYEEKILLYAKKVQ 1702 Query: 1059 NMEEEMQRVSKQLLDSKQHNEELQ 1082 + ++Q+VS+ K E Q Sbjct: 1703 QLSRKLQKVSENQSPQKPKPAETQ 1726 Score = 123 bits (296), Expect = 5e-26 Identities = 178/874 (20%), Positives = 383/874 (43%), Gaps = 66/874 (7%) Query: 730 EKISELLAKINHEEQSKIQTQFGIDAKIQERDLY--IENIESELSKYKSRICRLEESIAV 787 +KI E K E + + +F +A + +D+Y +N E ++S+ + E+S+ + Sbjct: 40 QKILEDAVKQRDEIIGQAEQKFK-EAASKYQDVYQKYQNNEKQISELAEKTLSQEKSLEI 98 Query: 788 MEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHE 847 + ++ +L S L+++ K E I ++E +N L + +R ++LL E Sbjct: 99 EYAKNKRFAQEILKLRSQLEKQNKENDEAKISDNEAINELIAEFNKER---RELLSKIEE 155 Query: 848 NKELQKKNQILLEENQNLQISL-SDMQQHYNALVEKANRTDLAESESTKYQTQ-LRDLES 905 ++ Q+ N E+ + + D Q + L+ + N + + S Q+Q L D S Sbjct: 156 LEKQQRMNSPDAEQISKPKDDIVDDFLQRIDELMRE-NESLKEQLASKPAQSQDLLDFSS 214 Query: 906 NLKRITHEHQTLIVQKKKE--IEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQ 963 N ++ +Q+ Q ++ + DL E +S D + LN+K + + + + + Q Sbjct: 215 NQNN-SNFNQSSNQQNSQQNMLLDLFGEQQPANQSQNTDIQRLNDKISQLEKELAEKDDQ 273 Query: 964 LQEYKNNIE------------NLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEI 1011 + E N IE NLN N E+ + + ++ + + + + E IN+I Sbjct: 274 INELANLIEENDKKQGTQQNQNLNQNDEDAIQSLVTKYEEEIDDIKKNNQNEKENLINQI 333 Query: 1012 NKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQL 1071 N+L LK K+ I+ +N ++ DYE+K+ T LE +++ +S++L Sbjct: 334 NELKNSLKNKE---ISSENDLNEMKIIIEQTSKDYETKIQDLMTNLEENSQKLNEMSQKL 390 Query: 1072 LDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXX 1131 +S++ N++L + Q E KE + N+ K E + + + ++ N + Sbjct: 391 KESEEKNQKLNEMSMLQASNDAE-KEKFIKEISNLTK-ENEKLQTVLN--ENEKNRTENE 446 Query: 1132 XXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVV 1191 V E ++ + + E + L TE+++ T+I++ E N E ++ Sbjct: 447 RL----------VAENQKLNSDLHEIGEVNKNLQTEIEKL-TEIMKSEQNNKENEMMSLL 495 Query: 1192 NQ--EQINQLKSKLEQLNTEND----NLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQ 1245 +Q EQ+ L+ KL Q N E + +L + +L + D +I E+ +Q+ + Sbjct: 496 SQKEEQVQALQVKLNQTNQEKEKQFEDLSQKLKQLEAEKQKLNDDYESKINEI-QQNDNE 554 Query: 1246 READFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTME-QVTSLQNKLQDKEE 1304 ++Q E+ + +++ + L + + + + + K++++E Q+ +N + +E Sbjct: 555 TFTNYQNQIKEMMINNENLQNENKSLQEKISLNEKSDNEKVLSLEEQLKESKNSISSLQE 614 Query: 1305 HLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQE 1364 L++ Q+ ++ I +SE +EK+ +L+ E +S ++ Sbjct: 615 QLKSSQQTIENLEKNISE-KSETYNEKIK---SLTDELSTIQNTNENLQNEIKSLQEKLS 670 Query: 1365 QSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYT 1424 + N NE+ L++ +++ E + ++ +L L + E+ T + Sbjct: 671 NNEKNDNEKILNLEEQLKNSQNEVRIGQEKLSKFENEYDQMRSKLSLMEKEL--STSQKM 728 Query: 1425 ITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIER 1484 Q+ E E++++++ EK + E +L +YE +KE + + Sbjct: 729 KESLQK--EKESLQEKISLSEKSDNEKVLSLEEQLN----NSKNMITNYEQNEKELQSQL 782 Query: 1485 VKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALEN--QEIEIVTLNDE--I 1540 L EEL+ +L ++++ K +E+V E + N E++ +T ++E I Sbjct: 783 STLNEELSTSKKMIETLEEKISNNEKNGDEKVKSYEEQLNSYRNTINELQQITQSNEEKI 842 Query: 1541 TNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDN 1574 +L++ + KI SD ++ + QL+N Sbjct: 843 KSLESQNKDLQEKISLSEKSESDKEKSYEAQLNN 876 Score = 104 bits (249), Expect = 2e-20 Identities = 165/856 (19%), Positives = 359/856 (41%), Gaps = 67/856 (7%) Query: 749 TQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQE 808 T + K + + + + ++ KY LE+++ ++ E+K + S Q+ Sbjct: 11 TSSELKEKYNQLAIKYKKAKEDIDKYSHNQKILEDAVKQRDEIIGQAEQKFKEAASKYQD 70 Query: 809 KQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQK-KNQILLEENQNLQI 867 Y +Y E ++ + ++ +E + + + +E+ K ++Q+ + +N + Sbjct: 71 ---VYQKYQNNEKQISELAEKTLSQEKSLEIEYAKNKRFAQEILKLRSQLEKQNKENDEA 127 Query: 868 SLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIED 927 +SD + N L+ + N+ E + +++ +LE +R+ I + K +I D Sbjct: 128 KISD-NEAINELIAEFNK------ERRELLSKIEELEKQ-QRMNSPDAEQISKPKDDIVD 179 Query: 928 LEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLE 987 +F +I+ +R+ + L E+ L +NN N N + + N Sbjct: 180 ---DFLQRIDELMRENESLKEQLASKPAQSQDL-LDFSSNQNN-SNFNQSSNQQNSQQNM 234 Query: 988 LIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYE 1047 L+D ++Q T +I +LN + Q ++E+ + +IN +++ + +D + Sbjct: 235 LLDLFGEQQPANQSQNT-----DIQRLNDKISQLEKELAEKDDQIN--ELANLIEENDKK 287 Query: 1048 SKLAQFTTKLENMEEEMQ----RVSKQLLDSKQHNE-ELQILVREQDDQIKELKETKLTF 1102 Q +N E+ +Q + +++ D K++N+ E + L+ + ++ LK +++ Sbjct: 288 QGTQQNQNLNQNDEDAIQSLVTKYEEEIDDIKKNNQNEKENLINQINELKNSLKNKEISS 347 Query: 1103 EMNIPKTEGMIISSTIE----PMSDDANNVDXXXXXXXXXXXXLKVQEEE-EFIQERSVL 1157 E ++ + + +II T + + D N++ LK EE+ + + E S+L Sbjct: 348 ENDLNEMK-IIIEQTSKDYETKIQDLMTNLEENSQKLNEMSQKLKESEEKNQKLNEMSML 406 Query: 1158 Q----EQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQI--NQ-LKSKLEQLNTEN 1210 Q + K E+ + +L+T+ E + N+ + NQ L S L ++ N Sbjct: 407 QASNDAEKEKFIKEISNLTKENEKLQTVLNENEKNRTENERLVAENQKLNSDLHEIGEVN 466 Query: 1211 DNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREA---DFQKTEHELRVQLSAFESK 1267 NL + + +L + S + + E+ L Q Q +A +T E Q K Sbjct: 467 KNLQTEIEKLTEIMKSEQNNKENEMMSLLSQKEEQVQALQVKLNQTNQEKEKQFEDLSQK 526 Query: 1268 YEQLLDSVQSSTQEETNKIVTMEQ-----VTSLQNKLQDKEEHLRNLQEKYADVINQIEI 1322 +QL Q + +KI ++Q T+ QN++++ + NLQ + + +I Sbjct: 527 LKQLEAEKQKLNDDYESKINEIQQNDNETFTNYQNQIKEMMINNENLQNENKSLQEKIS- 585 Query: 1323 LRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSX 1382 L + ++EKV L+ + +S +Q E NI+E++ + Sbjct: 586 LNEKSDNEKV---LSLEEQLKESKNSISSLQEQLKSSQQTIENLEKNISEKSETYNEKIK 642 Query: 1383 XXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLV 1442 + + ++ L +L + +K L +E +++L Sbjct: 643 SLTDELSTIQNTNENLQNEIKSLQEKLSNNEKNDNEKILNLEEQLKNSQNEVRIGQEKLS 702 Query: 1443 EYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLN 1502 ++E + + S+L+++ ++ + E++QKE E + K + ++E S N Sbjct: 703 KFENEYDQM----RSKLSLMEKELSTSQKMKESLQKEKESLQEK------ISLSEK-SDN 751 Query: 1503 KQVAELNKALEEEVAK-TNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFA 1561 ++V L + L TN Q E Q ++ TLN+E++ + M+ KI + Sbjct: 752 EKVLSLEEQLNNSKNMITNYEQNEKELQS-QLSTLNEELSTSKKMIETLEEKISNNEKNG 810 Query: 1562 SDTKQGRDEQLDNTMN 1577 + + +EQL++ N Sbjct: 811 DEKVKSYEEQLNSYRN 826 >UniRef50_Q23DH8 Cluster: DNA-directed RNA polymerase, omega subunit family protein; n=1; Tetrahymena thermophila SB210|Rep: DNA-directed RNA polymerase, omega subunit family protein - Tetrahymena thermophila SB210 Length = 4331 Score = 196 bits (478), Expect = 4e-48 Identities = 300/1466 (20%), Positives = 636/1466 (43%), Gaps = 125/1466 (8%) Query: 143 DVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXX 202 ++ L+ IK K+ ++ L ++K +E + L +I +KD +E KN+ Sbjct: 1896 EINELNEQIKLKNEQINKLDEQIKQLEEVLNQLNSQIKQKDLDLEYKNQLFDNLKLQYEE 1955 Query: 203 XXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEA 262 E K K+ E +E E Q+L+ + ++ + S E ++ L E Sbjct: 1956 QGQLLHNHQEKLKSNTIKLDEQNSMIE-----ENQQLISQLRTQ-LENSLKENSHSLNEQ 2009 Query: 263 ARF--EISLEHSKLAQELEQXXXXXXXXXXXXXXL---AKQSIEPSCEEKTEIEEKGSLE 317 +++ E ++ Q+ +Q L KQ + E + I+EK + Sbjct: 2010 ENSINQLNCELLQMGQDKQQLQGLIHQLKEENSNLNEDLKQKLNIISESQQLIKEKSDIA 2069 Query: 318 IANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRN 377 LT +++ + I+Q +EL+ ES+ ++ + + +N Sbjct: 2070 EELKQNLTNQLQKQQEYIQSIQQLQEELK--------ESQELNEKHINKIKQLEEQLQQN 2121 Query: 378 T--ASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDL---VDKEYVISEKD 432 T ++ +L S+ + + K +++I + + +I+S + +D E + + Sbjct: 2122 TEKIDNLEENIQKLISDKEQFEINNKQLQDQINQQDQLIESFEEQFQKQLDSESKLKLQA 2181 Query: 433 TXXXXXXXXXXGKDTLIAQ--LQLEHQQHMEGPSLIH-VGTNTEDVNEIAKVQEQLKQEL 489 T K+ L+ Q Q ++ E SL+ + N E++ + EQ+K+ Sbjct: 2182 TNLEESLKEAQQKEILLEQNLTQQLESKNSEIDSLVQKIKQNEEEIVVLNNNLEQIKESH 2241 Query: 490 NDEIKDV-NVKDLIEK----LKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTI 544 N+ + + N + L+++ L S+++ + QL ++ N ++ K+KQ+ + Sbjct: 2242 NEITQKLENTEQLLKQSEQDLNSSQKLVEQLEQNLEKINSENTHAIQEYEEKIKQLNSQV 2301 Query: 545 DNFSKVSDS-----------NKEIVRLTEELHHLSQKVAELEEEKGNL---QLHLVD-YD 589 ++ + DS N++I + L + E E+++ L + +L+D + Sbjct: 2302 ESLNNEKDSLASQFMDSDAQNQDIQLKLQSLQTELESKIEKEKQQAALIKEKQNLIDEKE 2361 Query: 590 SGRMIESDVYKKMIEMENLAETRLK-AISLLESQKFDLVQELHILQQKYDEVEDKLADIS 648 + S Y++ E +L+ + LE + ++EL I ++ E+++KL D+ Sbjct: 2362 QAIQLLSTEYEQREEQSQQVNKQLQHKLEALEERLTSKIEELKIQNEQNQELQNKLEDLI 2421 Query: 649 QLQSDQVCSEIKSVH---LEEQ----IDALSASKKELALVIENLKLDKEQLYGTIKDLEN 701 Q ++ Q +I H L+E+ + L ++E ++ + +K++ +K ++ Sbjct: 2422 Q-ETQQKIEKINDQHQLGLQEKDNYYQELLKQKEQEQMNLLNDQLSEKQKQEEFMKCMQQ 2480 Query: 702 DKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERD 761 ++ +LQ Q DL + E E IS + +Q +I + I +++E+ Sbjct: 2481 QEQRFQEQLQITQQNAQDLVQQKEIHYKEIISMKDEDLMKRKQ-EIHEKEEIKQQLEEK- 2538 Query: 762 LYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTI--- 818 I N+++EL K I + I ED + SL ++ D+L LQE + E + Sbjct: 2539 --IFNLQNELQNLKEEILQKNNDIHRQEDIQISLNKQIDELKKNLQESLQKQEESALILL 2596 Query: 819 -QEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYN 877 +E+ + + + ++ ++ QL EN++ Q + ++L++ +++ + N Sbjct: 2597 ERENNIKQQEQAQVSQNKEID-QLKNKLQENEQKQNEMALILQDKEHVMKEQEEKLISLN 2655 Query: 878 ALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIE 937 + N T L E+ + L LE K I+ E Q IVQ + +I E++ TQ++ Sbjct: 2656 NEINNLNNT-LKENLQKVSERDLVLLEKE-KDIS-ELQEQIVQLQDKISSSELQI-TQLQ 2711 Query: 938 S-AIRDKKVLNEKY-------EKNIEYVTQLEAQLQEYKNNIENL-NMNVEEL--NKMNL 986 S +I ++ LN K + ++ + L+ Q+QE + +I++L + + EL K N Sbjct: 2712 SNSINKEEELNSKLAQQASDNQNQLKLIEDLKNQIQELEKSIDSLEQLKINELQDQKNNY 2771 Query: 987 ELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDY 1046 EL K+ +++ + + Y +I + + ++++ + +I + Q++ ++ +SD+ Sbjct: 2772 ELSIKNFEEEIKK---IKQDYETKIQENSQIIEELNVQIKSFEQQLELQKIQNKQQLSDH 2828 Query: 1047 ESKLAQFTTKLENMEEEMQ-----RVSKQLLDSKQ-HNEELQILVREQDDQIKELKETKL 1100 E + Q + N + E+Q + + +Q HN+++ + E +++ K +K+ Sbjct: 2829 EEYVKQLQEEFNNKKLELQKEYETKAGASFSEIEQLHNQKINKMQEEFEEKHKNMKD--- 2885 Query: 1101 TFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQ 1160 + + I K + +E + ++ K +++++ QE ++ Sbjct: 2886 SLQSEIKK-----LQEDLEAQIQENKKLNLQIQELDSELLNAK-EQKQKISQEVDETLQK 2939 Query: 1161 SAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAEL 1220 + +LN ++Q+ +I Q+ L ++ +Q++IN L+ K E+ E +L Sbjct: 2940 NVELNDKIQQ---QIEQINNLLSKQNEERQSHQDEINLLQEKFEKQLEEVQK--QNQVKL 2994 Query: 1221 RSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQ 1280 S S EI +L + Q+EA K ++EL QLS + + + L +++ Sbjct: 2995 EQSHSEVEQSHQSEIQQLLQN---QQEA-ILKLKNELTEQLSKVQQENDLLEKQLRAKES 3050 Query: 1281 EETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQI---EILRSEIEDEKVAFXXX 1337 EE ++++ +++Q+KE L +L+E+ +I ++ E +++E+ +E Sbjct: 3051 EEEQ---LNDKLSQQYDQIQEKESDLVSLKEENNKLIQKVQNFEKIKNELVEENNQLKQN 3107 Query: 1338 XXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVND 1397 +L Q Q +EQ I + N +N Q K+S Sbjct: 3108 IVELENSSAEISANLEKLIQE-NQDKEQQIYDFN-DNLQQKESQIQELNSKILQIEEKYQ 3165 Query: 1398 AEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKES 1457 + + LE HQ+++KD E T+ L ++ +F+ L E + +E YE Sbjct: 3166 TQIQELEKNHQVKIKDLADKFTVCEDTLVLQEK--QFQEKLSNLQE-KYNLEQTNYE--- 3219 Query: 1458 ELAILRLKMHENAN-HYETMQKESEIERV---KLIEELNVKITESVSLNKQVAELNKALE 1513 L I + N E +QK+ E + K EE ++ S +L +Q +L+K E Sbjct: 3220 SLQIDHQNIQSQLNLLQEELQKQIEGNHILSQKQQEEKDLVSENSQNLQQQNLDLHKENE 3279 Query: 1514 EEVAKTNEMQTALENQEIEIVTLNDE 1539 E AK +M+ L E +I +ND+ Sbjct: 3280 ESKAKIQQMKEKLSQLEEQIEKVNDD 3305 Score = 196 bits (477), Expect = 6e-48 Identities = 305/1505 (20%), Positives = 656/1505 (43%), Gaps = 126/1505 (8%) Query: 154 KDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXED 213 K N + LQ + + +++ I LQE++ E ++ E K+ E+ Sbjct: 2073 KQNLTNQLQKQQEYIQS-IQQLQEELKESQELNE-KHINKIKQLEEQLQQNTEKIDNLEE 2130 Query: 214 TKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISS-LEEANKL-LEAARFEISLEH 271 Q++ +E F + +D+ + + IES + + L+ +KL L+A E SL+ Sbjct: 2131 NIQKLISDKEQFEINNKQLQDQINQQDQLIESFEEQFQKQLDSESKLKLQATNLEESLKE 2190 Query: 272 SKLAQEL-EQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIEL 330 ++ + L EQ Q I+ + EE + + E+T+K+E Sbjct: 2191 AQQKEILLEQNLTQQLESKNSEIDSLVQKIKQNEEEIVVLNNNLEQIKESHNEITQKLEN 2250 Query: 331 LEHLNCQIRQTN-------KELENKLATMGTESK-AVSSPSKKGSPLISR-KSGRNTASK 381 E L Q Q ++LE L + +E+ A+ +K L S+ +S N Sbjct: 2251 TEQLLKQSEQDLNSSQKLVEQLEQNLEKINSENTHAIQEYEEKIKQLNSQVESLNNEKDS 2310 Query: 382 MKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKD---LVDKEYVISEKDTXXXXX 438 + S + + S+ NQD K+ + +LE I+ + + +K+ +I EK+ Sbjct: 2311 LASQF--MDSDAQNQDIQLKLQSLQ-TELESKIEKEKQQAALIKEKQNLIDEKEQAIQLL 2367 Query: 439 XXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNV 498 ++ Q+ + Q +E T + E+ K+Q + QEL ++++D+ + Sbjct: 2368 STEYEQREEQSQQVNKQLQHKLEALE----ERLTSKIEEL-KIQNEQNQELQNKLEDL-I 2421 Query: 499 KDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKL-----KLKQMQKTIDNFSKVSDS 553 ++ +K++ +Q E D + ++K K ++ +L + QK + F K Sbjct: 2422 QETQQKIEKINDQHQLGLQEKDNYYQELLKQKEQEQMNLLNDQLSEKQKQ-EEFMKCMQQ 2480 Query: 554 NKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRL 613 ++ R E+L Q +L ++K ++H + S M + D+ K+ E+ E + Sbjct: 2481 QEQ--RFQEQLQITQQNAQDLVQQK---EIHYKEIIS--MKDEDLMKRKQEIHEKEEIKQ 2533 Query: 614 KAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSA 673 + LE + F+L EL L++ E+ K DI + + Q+ + L++ + Sbjct: 2534 Q----LEEKIFNLQNELQNLKE---EILQKNNDIHRQEDIQISLNKQIDELKKNLQESLQ 2586 Query: 674 SKKELALVI----ENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSA 729 ++E AL++ N+K ++ K+++ K + Q + + L DK M Sbjct: 2587 KQEESALILLERENNIKQQEQAQVSQNKEIDQLKNKLQENEQKQNEMALILQDKEHVMKE 2646 Query: 730 EKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVME 789 ++ E L +N+E + T K+ ERDL + E ++S+ L+E I ++ Sbjct: 2647 QE--EKLISLNNEINNLNNTLKENLQKVSERDLVLLEKEKDISE-------LQEQIVQLQ 2697 Query: 790 DRRYSLERKADQLGSY-LQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHEN 848 D+ S E + QL S + ++++ S+ Q + N+L ++ D ++ Q+ E+E Sbjct: 2698 DKISSSELQITQLQSNSINKEEELNSKLAQQASDNQNQLKLIED----LKNQIQELEKSI 2753 Query: 849 KELQK-KNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNL 907 L++ K L ++ N ++S+ + ++ +++ T + E+ + +L + Sbjct: 2754 DSLEQLKINELQDQKNNYELSIKNFEEEIKK-IKQDYETKIQENSQI-----IEELNVQI 2807 Query: 908 KRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEY 967 K + + +Q K+++ D E E+ Q++ +KK+ +K EY T+ A E Sbjct: 2808 KSFEQQLELQKIQNKQQLSDHE-EYVKQLQEEFNNKKLELQK-----EYETKAGASFSE- 2860 Query: 968 KNNIENLNMNVEELNKMNLELIDKH------VQKQQTQSPDYTEQYINEINKLNALLKQK 1021 IE L+ +++NKM E +KH +Q + + + E I E KLN +++ Sbjct: 2861 ---IEQLHN--QKINKMQEEFEEKHKNMKDSLQSEIKKLQEDLEAQIQENKKLNLQIQEL 2915 Query: 1022 DEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRV-SKQLLDSKQHNEE 1080 D E+ LN K ++S V + K + K++ E++ + SKQ + + H +E Sbjct: 2916 DSEL--LNAKEQKQKIS--QEVDETLQKNVELNDKIQQQIEQINNLLSKQNEERQSHQDE 2971 Query: 1081 LQILVREQDDQIKEL-KETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXX 1139 + +L + + Q++E+ K+ ++ E + + E S + + + + Sbjct: 2972 INLLQEKFEKQLEEVQKQNQVKLEQSHSEVEQSHQSEIQQLLQNQQEAI--LKLKNELTE 3029 Query: 1140 XXLKVQEEEEFIQERSVLQE-QSAKLNTELQECYTKI-------IQLETLNTELTGHDVV 1191 KVQ+E + ++++ +E + +LN +L + Y +I + L+ N +L V Sbjct: 3030 QLSKVQQENDLLEKQLRAKESEEEQLNDKLSQQYDQIQEKESDLVSLKEENNKLI-QKVQ 3088 Query: 1192 NQEQI-NQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELW--KQHLAQREA 1248 N E+I N+L + QL L ++ AE+ +++ + + + +++ +L Q+E+ Sbjct: 3089 NFEKIKNELVEENNQLKQNIVELENSSAEISANLEKLIQENQDKEQQIYDFNDNLQQKES 3148 Query: 1249 DFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRN 1308 Q+ ++ ++++ ++L + Q ++ +K E LQ K +E L N Sbjct: 3149 QIQELNSKILQIEEKYQTQIQELEKNHQVKIKDLADKFTVCEDTLVLQEK--QFQEKLSN 3206 Query: 1309 LQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSY-KQMQEQSI 1367 LQEKY + Q +I+ + + + ++ Q K + ++ Sbjct: 3207 LQEKYN--LEQTNYESLQIDHQNIQSQLNLLQEELQKQIEGNHILSQKQQEEKDLVSENS 3264 Query: 1368 LNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITL 1427 N+ ++N L K + +++ E ++ ++ + E + E + Sbjct: 3265 QNLQQQNLDLHKENEESKAKIQQMKEKLSQLEEQIEKVNDDKQKSQEENEKMRIEKETEI 3324 Query: 1428 TQRNDEFENVRQQLVEYEKRIEDLTYE-KESELAILRLKMHENANHYETMQKESEIERVK 1486 ++ E + ++ Q+ + E +E+ T + + + + + + K + + + E +++++ Sbjct: 3325 EEKEKEIQKLKVQIQDLEGVMEEQTQQIQTANVEVEKFKKDLDERYNQIAFLEDILKQLE 3384 Query: 1487 LIEELNVKITESVSLNKQVAELNK--ALEEEVAKTNEMQTALE---NQEIEIVT-LNDEI 1540 E+ N++ T + N + E N+ +EE + N+ T L+ +EI+ L ++ Sbjct: 3385 E-EKNNLQNTLNECDNALIQERNERATVEETINLLNDKITNLQIEREDNLEIIEKLKADL 3443 Query: 1541 TNLQNMVRASSS-KIQ-KHVSFASDTKQGRDEQLDNTM--NKELLDAVPRAELDLAMYML 1596 Q + SS K+ S + + + +Q+D N ELLD + EL++ Y Sbjct: 3444 LQSQPQKQNSSPIKLSLPQTSSQAGSSSAQKQQIDQLTFANAELLDQINELELEIKEYQR 3503 Query: 1597 HQRDV 1601 + ++ Sbjct: 3504 EKEEI 3508 Score = 193 bits (471), Expect = 3e-47 Identities = 294/1456 (20%), Positives = 641/1456 (44%), Gaps = 141/1456 (9%) Query: 166 KIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENF 225 KI + L LQEK N ++++ K + + +QQ + QE Sbjct: 2430 KINDQHQLGLQEKDNYYQELLKQKEQEQMNLLNDQLSEKQKQEEFMKCMQQQEQRFQEQL 2489 Query: 226 IAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXX 285 + +D Q+ K+I K++ IS +E L + EI E ++ Q+LE+ Sbjct: 2490 QITQQNAQDLVQQ--KEIHYKEI-ISMKDED---LMKRKQEIH-EKEEIKQQLEEKIFNL 2542 Query: 286 XXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKEL 345 K+ I ++ +I + ++I+ L K+I+ L+ N Q K+ Sbjct: 2543 QNELQNL----KEEI---LQKNNDIHRQEDIQIS----LNKQIDELKK-NLQ-ESLQKQE 2589 Query: 346 ENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKN 405 E+ L + E+ + S +N + + ++++ +++ K + Sbjct: 2590 ESALILLERENNIKQQEQAQVSQNKEIDQLKNKLQENEQKQNEMALILQDKEHVMKEQEE 2649 Query: 406 EIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSL 465 ++ L I +LN L + +SE+D I QLQ + L Sbjct: 2650 KLISLNNEINNLNNTLKENLQKVSERDLVLLEKEKDISELQEQIVQLQ----DKISSSEL 2705 Query: 466 IHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKN 525 + +N+ ++ +L Q+ +D + N LIE LK+ +++ + D ++ N Sbjct: 2706 QITQLQSNSINKEEELNSKLAQQASD---NQNQLKLIEDLKNQIQELEKSIDSLEQLKIN 2762 Query: 526 MIK-VKSNHKLKLKQMQKTIDNFSKVSDSN-KEIVRLTEELH-HLSQKVAELEEEKGNLQ 582 ++ K+N++L +K ++ I + ++ +E ++ EEL+ + +LE +K + Sbjct: 2763 ELQDQKNNYELSIKNFEEEIKKIKQDYETKIQENSQIIEELNVQIKSFEQQLELQKIQNK 2822 Query: 583 LHLVDYDSG-RMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVE 641 L D++ + ++ + K +E++ ET+ A F +++LH QK ++++ Sbjct: 2823 QQLSDHEEYVKQLQEEFNNKKLELQKEYETKAGA-------SFSEIEQLH--NQKINKMQ 2873 Query: 642 DKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLEN 701 ++ + + D + SEIK L+E ++A K+L L I+ +LD E L + + Sbjct: 2874 EEFEEKHKNMKDSLQSEIKK--LQEDLEAQIQENKKLNLQIQ--ELDSELL-----NAKE 2924 Query: 702 DKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSK------IQTQFG--I 753 K+ I ++ +Q+N++L DK+++ E+I+ LL+K N E QS +Q +F + Sbjct: 2925 QKQKISQEVDETLQKNVELNDKIQQQ-IEQINNLLSKQNEERQSHQDEINLLQEKFEKQL 2983 Query: 754 DAKIQERDLYIENIESELSK-YKSRICRL----EESIAVMEDRRYSLERKADQLGSYLQE 808 + ++ + +E SE+ + ++S I +L +E+I +++ K Q L++ Sbjct: 2984 EEVQKQNQVKLEQSHSEVEQSHQSEIQQLLQNQQEAILKLKNELTEQLSKVQQENDLLEK 3043 Query: 809 KQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQI-------LLEE 861 + +A +E++L ++L+ D + E L+ ++ EN +L +K Q L+EE Sbjct: 3044 QLRAKES---EEEQLNDKLSQQYDQIQEKESDLVSLKEENNKLIQKVQNFEKIKNELVEE 3100 Query: 862 NQNLQISLSDMQQHYNALVE-KANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQ 920 N L+ ++ +++ N+ E AN L + K Q Q+ D NL+ + ++ I + Sbjct: 3101 NNQLKQNIVELE---NSSAEISANLEKLIQENQDKEQ-QIYDFNDNLQ----QKESQIQE 3152 Query: 921 KKKEIEDLEIEFNTQIESAIRDKKV----LNEKYEKNIEYVTQLEAQLQEYKNNIENLNM 976 +I +E ++ TQI+ ++ +V L +K+ + + E Q QE +N++ Sbjct: 3153 LNSKILQIEEKYQTQIQELEKNHQVKIKDLADKFTVCEDTLVLQEKQFQEKLSNLQE-KY 3211 Query: 977 NVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALN-QKINNA 1035 N+E+ N +L++ +++Q Q + ++ I E N + + +Q+++++++ N Q + Sbjct: 3212 NLEQTNYESLQIDHQNIQSQLNLLQEELQKQI-EGNHILSQKQQEEKDLVSENSQNLQQQ 3270 Query: 1036 QVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKEL 1095 + + ++K+ Q KL +EE++++V+ S++ NE+++I E++ +I+E Sbjct: 3271 NLDLHKENEESKAKIQQMKEKLSQLEEQIEKVNDDKQKSQEENEKMRI---EKETEIEEK 3327 Query: 1096 KETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERS 1155 ++ ++ I EG++ T + + NV+ ++ E+ +++ Sbjct: 3328 EKEIQKLKVQIQDLEGVMEEQTQQIQTA---NVEVEKFKKDLDERYNQIAFLEDILKQ-- 3382 Query: 1156 VLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLS 1215 L+E+ L L EC +IQ + +E IN L K+ L E ++ L Sbjct: 3383 -LEEEKNNLQNTLNECDNALIQERNERATV-------EETINLLNDKITNLQIEREDNLE 3434 Query: 1216 TVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSV 1275 + +L++ + + Q+ + + K L Q + + + + Q+ +LLD + Sbjct: 3435 IIEKLKADLLQSQPQK--QNSSPIKLSLPQTSSQAGSSSAQ-KQQIDQLTFANAELLDQI 3491 Query: 1276 QSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFX 1335 E E++ +KL + E L+ LQ + V ++E+ IED ++ Sbjct: 3492 NELELEIKEYQREKEEILDENDKLTKEIELLKGLQGEQP-VNRKVEL----IEDREIM-- 3544 Query: 1336 XXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRV 1395 +L+ NQ +Q+Q+Q ++ E + LK + Sbjct: 3545 -------------EQELQQLNQE-QQVQKQKRASLQNEMSDLKSILEQNIVVIQTLEEEI 3590 Query: 1396 NDAEAKVLELTHQLELKDSEIYQKTHEYTIT---LTQRNDEFENVRQQLVEYEKRIEDLT 1452 + + K+ E L+LK Q + ++ L E +N++ Q+ + E+++ + Sbjct: 3591 VNYKKKLAEKEESLQLKQVANDQNSERFSKIEEELDISKHENQNLKNQITQLEQQLSEKD 3650 Query: 1453 YEKES------ELAILRLKMHENANHYETMQ--KESEIERVK-LIEELNVKITESVSLNK 1503 Y E EL+ + K + E ++ K+ +++K L++E N + K Sbjct: 3651 YHLEQQHNSICELSAMIEKFENQKSDAEVIENLKQMHTDKMKKLVKEHNEALASKDKEIK 3710 Query: 1504 QVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASD 1563 Q+ L K + E + N+ ++ E + ++ E+ N ++ S + ++ + Sbjct: 3711 QLTSLIKNINEVNEEQNKTISSFEQKHKSLIAERFELQNTIQELKDSLQQKEEQIQLFEK 3770 Query: 1564 TKQGRDEQLDNTMNKE 1579 + +T+ ++ Sbjct: 3771 KNDEMQAETQDTLKQQ 3786 Score = 192 bits (469), Expect = 5e-47 Identities = 323/1532 (21%), Positives = 644/1532 (42%), Gaps = 147/1532 (9%) Query: 90 ISESLANTLKQKEILMEKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSN 149 I +S N +K+ E +I + KE + + + Q L N Sbjct: 1759 IQQSYENKIKELEQNCLQIFEQKEELQIRISQLDEEIADLKSVEKKSFEEQTESTKSLEN 1818 Query: 150 TIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXX 209 TIKE +N ++ L + K ++ + I ++D+ I + + T Sbjct: 1819 TIKELENQINQLNEQNKKQNEQLVQQNQIIAQQDEQINEQTEQITQLNLQNNQQNEQIIE 1878 Query: 210 XXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISL 269 + Q K+ + +E L + I+ K+ +I+ L+E K LE +++ Sbjct: 1879 QNQQIISQNDKIDQQ--------NEEINELNEQIKLKNEQINKLDEQIKQLEEVLNQLNS 1930 Query: 270 EHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIE 329 + + +LE K + + K + EE+G L + +L Sbjct: 1931 QIKQKDLDLEY----------------KNQLFDNL--KLQYEEQGQLLHNHQEKLKSNTI 1972 Query: 330 LLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQL 389 L+ N I + N++L ++L T E+ S K ++ ++ ++ +QL Sbjct: 1973 KLDEQNSMIEE-NQQLISQLRTQ-LEN--------------SLKENSHSLNEQENSINQL 2016 Query: 390 SSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXG-KDTL 448 + E L DK+ + I +L+ +LN+DL K +ISE K L Sbjct: 2017 NCELLQMGQDKQQLQGLIHQLKEENSNLNEDLKQKLNIISESQQLIKEKSDIAEELKQNL 2076 Query: 449 IAQLQLEHQ-----QHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIE 503 QLQ + + Q ++ N + +N+I +++EQL+Q N E D N+++ I+ Sbjct: 2077 TNQLQKQQEYIQSIQQLQEELKESQELNEKHINKIKQLEEQLQQ--NTEKID-NLEENIQ 2133 Query: 504 KLKSAEEQITQLNDEI-DAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTE 562 KL S +EQ N ++ D N+ ++S +Q QK +D+ SK+ + L E Sbjct: 2134 KLISDKEQFEINNKQLQDQINQQDQLIESFE----EQFQKQLDSESKL---KLQATNLEE 2186 Query: 563 ELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQ 622 L QK LE+ NL L +S I+S V K E + + ES Sbjct: 2187 SLKEAQQKEILLEQ---NLTQQLESKNS--EIDSLVQKIKQNEEEIVVLNNNLEQIKESH 2241 Query: 623 KFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLE--EQIDALSASKKELAL 680 ++ Q+L +Q + E L + SQ +Q+ ++ ++ E I K+L Sbjct: 2242 N-EITQKLENTEQLLKQSEQDL-NSSQKLVEQLEQNLEKINSENTHAIQEYEEKIKQLNS 2299 Query: 681 VIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKIN 740 +E+L +K+ L D + +DI KLQ+ +Q ++ + EK A I E I+ Sbjct: 2300 QVESLNNEKDSLASQFMDSDAQNQDIQLKLQS-LQTELESKIEKEKQQAALIKEKQNLID 2358 Query: 741 HEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKAD 800 +EQ+ + + ++ + ++ +L + R+ E + + ++ L+ K + Sbjct: 2359 EKEQAIQLLSTEYEQREEQSQQVNKQLQHKLEALEERLTSKIEELKIQNEQNQELQNKLE 2418 Query: 801 QLGSYLQEK-QKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKE--------L 851 L Q+K +K ++ + E N L+ + LL + K+ + Sbjct: 2419 DLIQETQQKIEKINDQHQLGLQEKDNYYQELLKQKEQEQMNLLNDQLSEKQKQEEFMKCM 2478 Query: 852 QKKNQILLEENQNLQISLSDMQQ----HYNALVEKANRTDLAESESTKYQTQLR-DLESN 906 Q++ Q E+ Q Q + D+ Q HY ++ + + + + +++ LE Sbjct: 2479 QQQEQRFQEQLQITQQNAQDLVQQKEIHYKEIISMKDEDLMKRKQEIHEKEEIKQQLEEK 2538 Query: 907 LKRITHEHQTL---IVQKKKEI---EDLEIEFNTQIESAIRDKKVLNEKYEK-------- 952 + + +E Q L I+QK +I ED++I N QI+ ++ + +K E+ Sbjct: 2539 IFNLQNELQNLKEEILQKNNDIHRQEDIQISLNKQIDELKKNLQESLQKQEESALILLER 2598 Query: 953 --NIEYVTQLEAQLQEYKNNIEN-LNMNVEELNKMNLELIDK-HVQKQQTQSPDYTEQYI 1008 NI+ Q + + + ++N L N ++ N+M L L DK HV K+Q + Sbjct: 2599 ENNIKQQEQAQVSQNKEIDQLKNKLQENEQKQNEMALILQDKEHVMKEQEEK---LISLN 2655 Query: 1009 NEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVS 1068 NEIN LN LK+ +++ + + + +S+ + ++ Q K+ + E ++ ++ Sbjct: 2656 NEINNLNNTLKENLQKVSERDLVLLEKEKD----ISELQEQIVQLQDKISSSELQITQLQ 2711 Query: 1069 KQLLDSKQH-NEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANN 1127 ++ ++ N +L + +Q+K +++ K + + K+ + I + D NN Sbjct: 2712 SNSINKEEELNSKLAQQASDNQNQLKLIEDLKNQIQ-ELEKSIDSLEQLKINELQDQKNN 2770 Query: 1128 VDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNT--EL 1185 + +K Q+ E IQE S + E+ LN +++ + + ++L+ + +L Sbjct: 2771 YELSIKNFEEEIKKIK-QDYETKIQENSQIIEE---LNVQIKS-FEQQLELQKIQNKQQL 2825 Query: 1186 TGH-DVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLA 1244 + H + V Q Q KLE ++ +E+ + +++ E E K Sbjct: 2826 SDHEEYVKQLQEEFNNKKLELQKEYETKAGASFSEIEQLHNQKINKMQEEFEEKHKNMKD 2885 Query: 1245 QREADFQKTEHELRVQLSAFESKYEQL--LDSVQSSTQEETNKI-----VTMEQVTSLQN 1297 +++ +K + +L Q+ + Q+ LDS + +E+ KI T+++ L + Sbjct: 2886 SLQSEIKKLQEDLEAQIQENKKLNLQIQELDSELLNAKEQKQKISQEVDETLQKNVELND 2945 Query: 1298 KLQDKEEHLRNL----QEKYADVINQIEILRSEIEDE-KVAFXXXXXXXXXXXXXXXXDL 1352 K+Q + E + NL E+ ++I +L+ + E + + Sbjct: 2946 KIQQQIEQINNLLSKQNEERQSHQDEINLLQEKFEKQLEEVQKQNQVKLEQSHSEVEQSH 3005 Query: 1353 RTENQSYKQMQEQSILNI-NEENAQLKKSSXXXXXXXXXXXXRVNDAEA---KVLELTHQ 1408 ++E Q Q Q+++IL + NE QL K + ++ E K+ + Q Sbjct: 3006 QSEIQQLLQNQQEAILKLKNELTEQLSKVQQENDLLEKQLRAKESEEEQLNDKLSQQYDQ 3065 Query: 1409 LELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHE 1468 ++ K+S++ E L Q+ FE ++ +LVE +++ E E+ A + Sbjct: 3066 IQEKESDLVSLKEENN-KLIQKVQNFEKIKNELVEENNQLKQNIVELENSSAEI------ 3118 Query: 1469 NANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELN-KALEEEVAKTNEMQTALE 1527 +AN + +Q+ + E + I + N + + S Q+ ELN K L+ E ++Q + Sbjct: 3119 SANLEKLIQENQDKE--QQIYDFNDNLQQKES---QIQELNSKILQIEEKYQTQIQELEK 3173 Query: 1528 NQEIEIVTLNDEITNLQNMVRASSSKIQKHVS 1559 N +++I L D+ T ++ + + Q+ +S Sbjct: 3174 NHQVKIKDLADKFTVCEDTLVLQEKQFQEKLS 3205 Score = 189 bits (460), Expect = 6e-46 Identities = 279/1369 (20%), Positives = 596/1369 (43%), Gaps = 129/1369 (9%) Query: 235 EKQRLLKDIESKDVR--ISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXX 292 +KQ L + ++++V+ I +LE+ K L + E +++ L+Q Sbjct: 1121 KKQNQLLETQNQNVQKNIQTLEQTIKTLNEQNKSLQKEKESISKNLQQKTQNLAKSEDQV 1180 Query: 293 XXLAKQS---------IEPSCEEKTEIEEKGSLEIA------------------NMTELT 325 ++ +E +E E ++K S A + + Sbjct: 1181 AQFKNENKLYQEKCGILEKRIKELEETKKKSSTPSAGTSPNSKGKNQNTQQQQQQLQQYI 1240 Query: 326 KKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSP 385 K E L+ L + Q E E + + E + + S ++ +I ++ N K + Sbjct: 1241 KDCEQLKQLLIEYEQKFLEKEEDKSKLLAEIEDLKSKLEEAVTIIKQQEEENGKIKQNNQ 1300 Query: 386 WS-QLSSETLNQDTDKKINK-NEIAKLEMVIQSLNKDLVD-KEYVISEKDTXXXXXXXXX 442 S E L ++ ++ + + ++ K + I + +D ++ + +SEK Sbjct: 1301 NSTSFLKEKLKEEIEQNLKRVKDLEKEKEDIANEQQDKIELYQNSLSEKQQEIDELISKN 1360 Query: 443 XGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQL--KQELNDEIKDVNVKD 500 + LI Q Q E ++ E I ++++ +Q+QL K +L + +K+ ++ D Sbjct: 1361 NNLNELIDQYQREIKKCKEKMEEIKKMQEKVNLDQQKNMQDQLAQKNKLIEMMKNDSLDD 1420 Query: 501 LIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSK-VSDSNKEIVR 559 E+++ +++I +L ++ A + S + + K+ Q+ + F K + N++I + Sbjct: 1421 K-EEIELLKQEIEELKQQLQATQSKPLS-SSRQESQYKEFQQKEEEFKKLIKQQNEKIAK 1478 Query: 560 LTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIE-MENLAETRLKAISL 618 + ++ QK+ E EEE LQ L S +D KK + ++ + + I Sbjct: 1479 MEQD---CLQKM-EFEEEIARLQQEL---QSALDSHNDSGKKQNQSIDQIIND--QDIDG 1529 Query: 619 LESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVC--SEIKSV--HLEEQIDALSAS 674 L++++ + LQ++ E+E++ D+ ++Q+++ C +I+ + +E+ D L ++ Sbjct: 1530 LQNKR-NQQNSFEDLQERVKELEEENNDLREIQNERDCLQQQIQEIIDKNKEETDQLQST 1588 Query: 675 KKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLE----KMSAE 730 + L I+ ++D E++ +++ + + + IQ+ D+ E ++ E Sbjct: 1589 VRLLTQQIQKNQIDSEKIIQNLQNEIGSMTQFIKQQEQLIQQQNAEHDQKEIEFRQIIKE 1648 Query: 731 K----------ISELLAKINHEEQSKIQTQFGIDAKIQ--ERDLYIENIESELSKYKSRI 778 K I ++ +I + IQ Q I+ Q E+ L I N + S +I Sbjct: 1649 KDNYIFTQRDQIEQITDQIKEKNNQLIQMQENIEELKQNYEQQLQINNDQISNSNQNFQI 1708 Query: 779 CRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVE 838 ++E + E+ L + +QE +A S+ + E+ + +V+ Sbjct: 1709 -QIENLQKLREEEEKYQNSNLSDLNNQIQELNQALSQKEEELQEINMKQSVIQQ------ 1761 Query: 839 KQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTK-YQ 897 E++ KEL++ + E+ + LQI +S + + L ++ ++ESTK + Sbjct: 1762 ----SYENKIKELEQNCLQIFEQKEELQIRISQLDEEIADLKSVEKKSFEEQTESTKSLE 1817 Query: 898 TQLRDLESNLKRITHEHQ---TLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNI 954 +++LE+ + ++ +++ +VQ+ + I + + N Q E + N++ E+ I Sbjct: 1818 NTIKELENQINQLNEQNKKQNEQLVQQNQIIAQQDEQINEQTEQITQLNLQNNQQNEQII 1877 Query: 955 EYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKL 1014 E Q+ +Q + I+ N + ELN+ ++L ++ + K Q +Q +N+L Sbjct: 1878 EQNQQIISQ----NDKIDQQNEEINELNE-QIKLKNEQINKLDEQ----IKQLEEVLNQL 1928 Query: 1015 NALLKQKDEEIIALNQKINNAQVSYM---SMVSDYESKLAQFTTKLE---NMEEEMQRVS 1068 N+ +KQKD ++ NQ +N ++ Y ++ +++ KL T KL+ +M EE Q++ Sbjct: 1929 NSQIKQKDLDLEYKNQLFDNLKLQYEEQGQLLHNHQEKLKSNTIKLDEQNSMIEENQQLI 1988 Query: 1069 KQLLDSKQHN-EELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANN 1127 QL +++ +E + EQ++ I +L L + + +G+ I + ++ +N Sbjct: 1989 SQLRTQLENSLKENSHSLNEQENSINQLNCELLQMGQDKQQLQGL-----IHQLKEENSN 2043 Query: 1128 VDXXXXXXXXXXXXLKVQEEEEFIQERS-VLQEQSAKLNTELQECYTKIIQLETLNTELT 1186 ++ + E ++ I+E+S + +E L +LQ+ I ++ L EL Sbjct: 2044 LNEDLKQKLNI-----ISESQQLIKEKSDIAEELKQNLTNQLQKQQEYIQSIQQLQEELK 2098 Query: 1187 GHDVVNQEQINQLKSKLEQL--NTEN-DNLLSTVAELRSSISSAVDQRGFEIAELWKQ-H 1242 +N++ IN++K EQL NTE DNL + +L S D+ FEI Q Sbjct: 2099 ESQELNEKHINKIKQLEEQLQQNTEKIDNLEENIQKLIS------DKEQFEINNKQLQDQ 2152 Query: 1243 LAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDK 1302 + Q++ + E + + QL + ESK + +++ S +E K + +EQ +L +L+ K Sbjct: 2153 INQQDQLIESFEEQFQKQLDS-ESKLKLQATNLEESLKEAQQKEILLEQ--NLTQQLESK 2209 Query: 1303 EEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQM 1362 + +L +K +I +L + +E K + + N S K + Sbjct: 2210 NSEIDSLVQKIKQNEEEIVVLNNNLEQIKESHNEITQKLENTEQLLKQSEQDLNSSQKLV 2269 Query: 1363 Q--EQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKT 1420 + EQ++ IN EN + +N+ + + + ++ +I K Sbjct: 2270 EQLEQNLEKINSENTHAIQEYEEKIKQLNSQVESLNNEKDSLASQFMDSDAQNQDIQLKL 2329 Query: 1421 HEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKES 1480 T+ + E +QQ +++ ++L EKE + +L + + + + K+ Sbjct: 2330 QSLQ---TELESKIEKEKQQAALIKEK-QNLIDEKEQAIQLLSTEYEQREEQSQQVNKQL 2385 Query: 1481 EIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQ 1529 + + L E L KI E N+Q EL LE+ + +T + + +Q Sbjct: 2386 QHKLEALEERLTSKIEELKIQNEQNQELQNKLEDLIQETQQKIEKINDQ 2434 Score = 187 bits (456), Expect = 2e-45 Identities = 310/1476 (21%), Positives = 623/1476 (42%), Gaps = 159/1476 (10%) Query: 212 EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271 E Q+ + I M+ ++ KQ + ++ + +IS+ + F+I +E+ Sbjct: 1661 EQITDQIKEKNNQLIQMQENIEELKQNYEQQLQINNDQISNSNQ--------NFQIQIEN 1712 Query: 272 -SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIEL 330 KL +E E+ Q++ EE EI K S+ I E KI+ Sbjct: 1713 LQKLREEEEKYQNSNLSDLNNQIQELNQALSQKEEELQEINMKQSV-IQQSYE--NKIKE 1769 Query: 331 LEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKG--SPLISRKSGRNTASKMKSPWSQ 388 LE QI + +EL+ +++ + E + S KK S KS NT ++++ +Q Sbjct: 1770 LEQNCLQIFEQKEELQIRISQLDEEIADLKSVEKKSFEEQTESTKSLENTIKELENQINQ 1829 Query: 389 LSSETLNQDTDKKINKNEI-AKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDT 447 L+ + Q+ ++ + +N+I A+ + I + + ++++ ++ Sbjct: 1830 LNEQNKKQN-EQLVQQNQIIAQQDEQINEQTEQITQLNLQNNQQNEQIIEQNQQIISQND 1888 Query: 448 LIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKS 507 I Q E + E + E +N++ + +QL++ LN + KDL + K+ Sbjct: 1889 KIDQQNEEINELNE-----QIKLKNEQINKLDEQIKQLEEVLNQLNSQIKQKDLDLEYKN 1943 Query: 508 AEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIV-----RLTE 562 QL D + + ++ NH+ KLK +D + + + N++++ +L Sbjct: 1944 ------QLFDNLKLQYEEQGQLLHNHQEKLKSNTIKLDEQNSMIEENQQLISQLRTQLEN 1997 Query: 563 ELHHLSQKVAELEEEKGNLQLHLVDYDSGRM-IESDVYKKMIEMENLAETRLKAISLL-E 620 L S + E E L L+ + ++ +++ E NL E + ++++ E Sbjct: 1998 SLKENSHSLNEQENSINQLNCELLQMGQDKQQLQGLIHQLKEENSNLNEDLKQKLNIISE 2057 Query: 621 SQ-----KFDLVQEL-HILQQKYDEVEDKLADISQLQSD-QVCSEIKSVH------LEEQ 667 SQ K D+ +EL L + + ++ + I QLQ + + E+ H LEEQ Sbjct: 2058 SQQLIKEKSDIAEELKQNLTNQLQKQQEYIQSIQQLQEELKESQELNEKHINKIKQLEEQ 2117 Query: 668 IDALSASKKELALVIENLKLDKEQLYGTIKDLE---NDKEDIMNKLQNYIQENMDLTDKL 724 + + L I+ L DKEQ K L+ N ++ ++ + Q+ +D KL Sbjct: 2118 LQQNTEKIDNLEENIQKLISDKEQFEINNKQLQDQINQQDQLIESFEEQFQKQLDSESKL 2177 Query: 725 EKMSAEKISELLAKINHEE---QSKIQTQFG-----IDAKIQ-----ERDLYI-----EN 766 K+ A + E L + +E + + Q ID+ +Q E ++ + E Sbjct: 2178 -KLQATNLEESLKEAQQKEILLEQNLTQQLESKNSEIDSLVQKIKQNEEEIVVLNNNLEQ 2236 Query: 767 IESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQ----EKQKAYSEYTIQEDE 822 I+ ++ ++ E+ + E S ++ +QL L+ E A EY + + Sbjct: 2237 IKESHNEITQKLENTEQLLKQSEQDLNSSQKLVEQLEQNLEKINSENTHAIQEYEEKIKQ 2296 Query: 823 LVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEK 882 L +++ L + + Q ++ + +N+++Q K Q L E L+ + +Q + EK Sbjct: 2297 LNSQVESLNNEKDSLASQFMDSDAQNQDIQLKLQSLQTE---LESKIEKEKQQAALIKEK 2353 Query: 883 ANRTDLAESE----STKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEI--EFNTQI 936 N D E ST+Y+ + + K++ H+ + L + +IE+L+I E N ++ Sbjct: 2354 QNLIDEKEQAIQLLSTEYEQREEQSQQVNKQLQHKLEALEERLTSKIEELKIQNEQNQEL 2413 Query: 937 ESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENL--NMNVEELNKMNLELIDKHVQ 994 ++ + D ++ E +K + Q + LQE N + L E++N +N +L +K Q Sbjct: 2414 QNKLED--LIQETQQKIEKINDQHQLGLQEKDNYYQELLKQKEQEQMNLLNDQLSEKQKQ 2471 Query: 995 KQQTQSPDYTEQYINE---INKLNA--LLKQKDEEIIALNQKINNAQVSYMSMVSDYESK 1049 ++ + EQ E I + NA L++QK+ + + + + + E Sbjct: 2472 EEFMKCMQQQEQRFQEQLQITQQNAQDLVQQKEIHYKEIISMKDEDLMKRKQEIHEKEEI 2531 Query: 1050 LAQFTTKLENMEEEMQRVSKQLLDSKQ---HNEELQILVREQDDQIKE-LKETK------ 1099 Q K+ N++ E+Q + +++L E++QI + +Q D++K+ L+E+ Sbjct: 2532 KQQLEEKIFNLQNELQNLKEEILQKNNDIHRQEDIQISLNKQIDELKKNLQESLQKQEES 2591 Query: 1100 ----LTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERS 1155 L E NI + E +S E + N + L+ +E QE Sbjct: 2592 ALILLERENNIKQQEQAQVSQNKE-IDQLKNKLQENEQKQNEMALILQDKEHVMKEQEEK 2650 Query: 1156 V--LQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLE----QLNTE 1209 + L + LN L+E K+ + + + E QEQI QL+ K+ Q+ Sbjct: 2651 LISLNNEINNLNNTLKENLQKVSERDLVLLEKEKDISELQEQIVQLQDKISSSELQITQL 2710 Query: 1210 NDNLLSTVAELRSSISSAV--DQRGFEIAELWKQHLAQREADFQKTE----HELRVQLSA 1263 N ++ EL S ++ +Q ++ E K + + E E +EL+ Q + Sbjct: 2711 QSNSINKEEELNSKLAQQASDNQNQLKLIEDLKNQIQELEKSIDSLEQLKINELQDQKNN 2770 Query: 1264 FESKYEQLLDSVQSSTQEETNKIVTMEQVT---SLQNKLQDKEEHLRNLQEKY--ADVIN 1318 +E + + ++ Q+ KI Q+ ++Q K +++ L+ +Q K +D Sbjct: 2771 YELSIKNFEEEIKKIKQDYETKIQENSQIIEELNVQIKSFEQQLELQKIQNKQQLSDHEE 2830 Query: 1319 QIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLK 1378 ++ L+ E ++K+ L NQ +MQE+ E++ +K Sbjct: 2831 YVKQLQEEFNNKKLELQKEYETKAGASFSEIEQLH--NQKINKMQEE----FEEKHKNMK 2884 Query: 1379 KSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVR 1438 S ++++ +L LE + Q+ + + + + + E N + Sbjct: 2885 DS-----------------LQSEIKKLQEDLEAQ----IQENKKLNLQIQELDSELLNAK 2923 Query: 1439 QQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKE---SEIERVKLIEELNVKI 1495 +Q + + +++ T +K EL + E N+ + Q E S + + L++E K Sbjct: 2924 EQKQKISQEVDE-TLQKNVELNDKIQQQIEQINNLLSKQNEERQSHQDEINLLQEKFEKQ 2982 Query: 1496 TESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQ 1555 E V QV E E + +E+Q L+NQ+ I+ L +E+T + V+ + ++ Sbjct: 2983 LEEVQKQNQVKLEQSHSEVEQSHQSEIQQLLQNQQEAILKLKNELTEQLSKVQQENDLLE 3042 Query: 1556 KHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDL 1591 K + K+ +EQL++ ++++ D + E DL Sbjct: 3043 KQLR----AKESEEEQLNDKLSQQ-YDQIQEKESDL 3073 Score = 173 bits (421), Expect = 3e-41 Identities = 265/1337 (19%), Positives = 589/1337 (44%), Gaps = 110/1337 (8%) Query: 317 EIANMTELTKKIEL-LEHLNCQI--RQTNK--ELENKLATMGTESKAVSSPSKKGSPLIS 371 E+ N+ + ++I++ L+H ++ Q NK ELE KL E+ + S K+ L+ Sbjct: 987 ELDNIDDGFERIQIKLQHARQELDQEQANKIIELEKKLLIKQDETGRLESQIKELQQLVK 1046 Query: 372 RKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDL--VDKEYVIS 429 +++ +N++ K+++ + T++ + + ++ I L+ IQ L +++ + ++ I Sbjct: 1047 KQNKQNSSPKIQNQQQDSRNYTVSAAVETEEDQKLINSLQNQIQKLKQEIQKANTDFNII 1106 Query: 430 EKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQEL 489 + D K + + Q ++ Q + T E + K +E + + L Sbjct: 1107 KDDNKSFVSQIEILKKQNQLLETQNQNVQKNIQTLEQTIKTLNEQNKSLQKEKESISKNL 1166 Query: 490 NDEIKDV-NVKDLIEKLKSA-----------EEQITQLNDEIDAANKNMIKVKSNHKLKL 537 + +++ +D + + K+ E++I +L + ++ N K K Sbjct: 1167 QQKTQNLAKSEDQVAQFKNENKLYQEKCGILEKRIKELEETKKKSSTPSAGTSPNSKGK- 1225 Query: 538 KQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESD 597 Q T ++ K+ +L + L QK E EE+K L + D S ++ E+ Sbjct: 1226 --NQNTQQQQQQLQQYIKDCEQLKQLLIEYEQKFLEKEEDKSKLLAEIEDLKS-KLEEAV 1282 Query: 598 VYKKMIEMEN--LAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQV 655 K E EN + + + S L+ + L +E+ ++ ++E + DI+ Q D++ Sbjct: 1283 TIIKQQEEENGKIKQNNQNSTSFLKEK---LKEEIEQNLKRVKDLEKEKEDIANEQQDKI 1339 Query: 656 CSEIKSVHLEEQ-IDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYI 714 S+ ++Q ID L + L +I+ + + ++ +++++ +E + Q + Sbjct: 1340 ELYQNSLSEKQQEIDELISKNNNLNELIDQYQREIKKCKEKMEEIKKMQEKVNLDQQKNM 1399 Query: 715 QENMDLTDKL-EKMSAEKIS-----ELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIE 768 Q+ + +KL E M + + ELL + E + ++Q ++ + + Sbjct: 1400 QDQLAQKNKLIEMMKNDSLDDKEEIELLKQEIEELKQQLQATQSKPLSSSRQESQYKEFQ 1459 Query: 769 SELSKYKSRICRLEESIAVMED---RRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVN 825 + ++K I + E IA ME ++ E + +L LQ ++++ ++++ ++ Sbjct: 1460 QKEEEFKKLIKQQNEKIAKMEQDCLQKMEFEEEIARLQQELQSALDSHNDSGKKQNQSID 1519 Query: 826 RLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSD---MQQHYNALVEK 882 ++ D D + K+ + E +LQ++ + L EEN +L+ ++ +QQ +++K Sbjct: 1520 QIINDQDIDGLQNKRNQQNSFE--DLQERVKELEEENNDLREIQNERDCLQQQIQEIIDK 1577 Query: 883 ANRTDLAESEST-KYQTQ------------LRDLESNLKRITH---EHQTLIVQKKKEIE 926 N+ + + +ST + TQ +++L++ + +T + + LI Q+ E + Sbjct: 1578 -NKEETDQLQSTVRLLTQQIQKNQIDSEKIIQNLQNEIGSMTQFIKQQEQLIQQQNAEHD 1636 Query: 927 DLEIEFNTQIES------AIRDK--KVLNEKYEKNIEYVTQLEAQLQEYKNNIEN-LNMN 977 EIEF I+ RD+ ++ ++ EKN + + Q++ ++E K N E L +N Sbjct: 1637 QKEIEFRQIIKEKDNYIFTQRDQIEQITDQIKEKNNQLI-QMQENIEELKQNYEQQLQIN 1695 Query: 978 VEELNK--MNLELIDKHVQKQQTQSPDYTEQYI----NEINKLNALLKQKDEEIIALNQK 1031 ++++ N ++ +++QK + + Y + N+I +LN L QK+EE+ +N K Sbjct: 1696 NDQISNSNQNFQIQIENLQKLREEEEKYQNSNLSDLNNQIQELNQALSQKEEELQEINMK 1755 Query: 1032 INNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLD----SKQHNEELQILVRE 1087 + Q SY + + + E Q + E ++ + ++ +++ D K+ EE + Sbjct: 1756 QSVIQQSYENKIKELEQNCLQIFEQKEELQIRISQLDEEIADLKSVEKKSFEEQTESTKS 1815 Query: 1088 QDDQIKELK-ETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQE 1146 ++ IKEL+ + E N + E ++ + I D+ N Q+ Sbjct: 1816 LENTIKELENQINQLNEQNKKQNEQLVQQNQIIAQQDEQINEQTEQITQLNLQNN---QQ 1872 Query: 1147 EEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQL 1206 E+ I++ + Q+ K++ + +E Q++ N ++ D EQI QL+ L QL Sbjct: 1873 NEQIIEQNQQIISQNDKIDQQNEEINELNEQIKLKNEQINKLD----EQIKQLEEVLNQL 1928 Query: 1207 NTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFES 1266 N++ E ++ + + + E +L H + +++ K + E + + Sbjct: 1929 NSQIKQ-KDLDLEYKNQLFDNLKLQYEEQGQLLHNHQEKLKSNTIKLD-EQNSMIEENQQ 1986 Query: 1267 KYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSE 1326 QL +++S +E ++ + EQ S+ N+L + + +++ +I+Q++ S Sbjct: 1987 LISQLRTQLENSLKENSHSL--NEQENSI-NQLNCELLQMGQDKQQLQGLIHQLKEENSN 2043 Query: 1327 IED---EKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXX 1383 + + +K+ +L+ + Q Q++ I +I + +LK+S Sbjct: 2044 LNEDLKQKLNIISESQQLIKEKSDIAEELKQNLTNQLQKQQEYIQSIQQLQEELKESQ-E 2102 Query: 1384 XXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVE 1443 ++ + + E LE ++ ++ I Q D+ N + QL+E Sbjct: 2103 LNEKHINKIKQLEEQLQQNTEKIDNLEENIQKLISDKEQFEINNKQLQDQI-NQQDQLIE 2161 Query: 1444 -YEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSL- 1501 +E++ + + ES+L + + E+ E QKE +E+ L ++L K +E SL Sbjct: 2162 SFEEQFQK-QLDSESKLKLQATNLEESLK--EAQQKEILLEQ-NLTQQLESKNSEIDSLV 2217 Query: 1502 ------NKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQ 1555 +++ LN LE+ NE+ LEN E + ++ + Q +V ++ Sbjct: 2218 QKIKQNEEEIVVLNNNLEQIKESHNEITQKLENTEQLLKQSEQDLNSSQKLVEQLEQNLE 2277 Query: 1556 KHVSFASDTKQGRDEQL 1572 K S + Q +E++ Sbjct: 2278 KINSENTHAIQEYEEKI 2294 Score = 167 bits (407), Expect = 2e-39 Identities = 302/1452 (20%), Positives = 637/1452 (43%), Gaps = 162/1452 (11%) Query: 149 NTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXX 208 + +KE++ L L ++ + T+ + +K++E+D ++ K K + Sbjct: 2642 HVMKEQEEKLISLNNEINNLNNTLKENLQKVSERDLVLLEKEKDISELQEQIVQLQDKIS 2701 Query: 209 XXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEIS 268 ++ Q+T++Q N I E E + + D +++ I L+ N++ E + S Sbjct: 2702 S----SELQITQLQSNSINKEEELNSKLAQQASDNQNQLKLIEDLK--NQIQELEKSIDS 2755 Query: 269 LEHSKLAQELEQXXXXXXXXXXXXXXLAK--QSIEPSCEEKTEIEEKGSLEIANMT---E 323 LE K+ + +Q + K Q E +E ++I E+ +++I + E Sbjct: 2756 LEQLKINELQDQKNNYELSIKNFEEEIKKIKQDYETKIQENSQIIEELNVQIKSFEQQLE 2815 Query: 324 LTK---KIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPS-KKGSPLISRKSGR--- 376 L K K +L +H ++Q +E NK + E + + S + L ++K + Sbjct: 2816 LQKIQNKQQLSDHEE-YVKQLQEEFNNKKLELQKEYETKAGASFSEIEQLHNQKINKMQE 2874 Query: 377 NTASKMKSPWSQLSSET--LNQDTDKKINKNEIAKLEMVIQSLNKDLV---DKEYVISEK 431 K K+ L SE L +D + +I +N+ KL + IQ L+ +L+ +++ IS++ Sbjct: 2875 EFEEKHKNMKDSLQSEIKKLQEDLEAQIQENK--KLNLQIQELDSELLNAKEQKQKISQE 2932 Query: 432 DTXXXXXXXXXXGK--------DTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQE 483 K + L+++ E Q H + +L+ + + E+ K + Sbjct: 2933 VDETLQKNVELNDKIQQQIEQINNLLSKQNEERQSHQDEINLLQEKFEKQ-LEEVQKQNQ 2991 Query: 484 QLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQ-- 541 ++ + E++ + ++ + L++ +E I +L +E+ + + KV+ + L KQ++ Sbjct: 2992 VKLEQSHSEVEQSHQSEIQQLLQNQQEAILKLKNEL---TEQLSKVQQENDLLEKQLRAK 3048 Query: 542 ---------KTIDNFSKVSDSNKEIVRLTEELHHLSQKVA-------ELEEEKGNLQLHL 585 K + ++ + ++V L EE + L QKV EL EE L+ ++ Sbjct: 3049 ESEEEQLNDKLSQQYDQIQEKESDLVSLKEENNKLIQKVQNFEKIKNELVEENNQLKQNI 3108 Query: 586 VDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLA 645 V+ ++ S +K+I+ E ++ + QK +QEL+ K ++E+K Sbjct: 3109 VELENSSAEISANLEKLIQENQDKEQQIYDFNDNLQQKESQIQELN---SKILQIEEKYQ 3165 Query: 646 DISQLQSDQVCSEIKSVHLEEQI----DALSASKKELALVIENLKLDKEQLYGT-IKDLE 700 +Q+Q + ++K L ++ D L +K+ + NL+ +K L T + L+ Sbjct: 3166 --TQIQELEKNHQVKIKDLADKFTVCEDTLVLQEKQFQEKLSNLQ-EKYNLEQTNYESLQ 3222 Query: 701 NDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQER 760 D ++I ++L N +QE +L ++E + +L++ EE+ + ++ + + Q Sbjct: 3223 IDHQNIQSQL-NLLQE--ELQKQIEG------NHILSQKQQEEKDLV-SENSQNLQQQNL 3272 Query: 761 DLYIENIESE--LSKYKSRICRLEESIAVMEDRRYSLERKADQLG----SYLQEKQKAYS 814 DL+ EN ES+ + + K ++ +LEE I + D + + + +++ + ++EK+K Sbjct: 3273 DLHKENEESKAKIQQMKEKLSQLEEQIEKVNDDKQKSQEENEKMRIEKETEIEEKEKEIQ 3332 Query: 815 EYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKK-NQI---------LLEENQN 864 + +Q +L V+ + + ++ +E+E K+L ++ NQI L EE N Sbjct: 3333 KLKVQIQDLEG---VMEEQTQQIQTANVEVEKFKKDLDERYNQIAFLEDILKQLEEEKNN 3389 Query: 865 LQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDL----ESNLKRITHEHQTLIVQ 920 LQ +L++ NAL+++ N E ++ +L E NL+ I L+ Sbjct: 3390 LQNTLNECD---NALIQERNERATVEETINLLNDKITNLQIEREDNLEIIEKLKADLLQS 3446 Query: 921 KKKEIEDLEIEFN-----TQIESAIRDKKVLNEKYEKNIEYVTQ---LEAQLQEYKNNIE 972 + ++ I+ + +Q S+ K+ +++ N E + Q LE +++EY+ E Sbjct: 3447 QPQKQNSSPIKLSLPQTSSQAGSSSAQKQQIDQLTFANAELLDQINELELEIKEYQREKE 3506 Query: 973 NLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKI 1032 + ++L K +EL+ K +Q +Q + + I + + L+Q ++E QK Sbjct: 3507 EILDENDKLTK-EIELL-KGLQGEQPVNRKV--ELIEDREIMEQELQQLNQEQQVQKQK- 3561 Query: 1033 NNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQI 1092 + S + +SD +S L Q ++ +EEE+ K+L + K+ + +L+ + +Q+ + Sbjct: 3562 ---RASLQNEMSDLKSILEQNIVVIQTLEEEIVNYKKKLAE-KEESLQLKQVANDQNSE- 3616 Query: 1093 KELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEE---- 1148 + +K+ E++I K E + + I + + D L E+ Sbjct: 3617 ---RFSKIEEELDISKHENQNLKNQITQLEQQLSEKDYHLEQQHNSICELSAMIEKFENQ 3673 Query: 1149 ----EFIQE-RSVLQEQSAKLNTELQECY-TKIIQLETLNTELTGHDVVNQEQ---INQL 1199 E I+ + + ++ KL E E +K +++ L + + + VN+EQ I+ Sbjct: 3674 KSDAEVIENLKQMHTDKMKKLVKEHNEALASKDKEIKQLTSLIKNINEVNEEQNKTISSF 3733 Query: 1200 KSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRV 1259 + K + L E L +T+ EL+ S+ +Q ++ E + D K + EL Sbjct: 3734 EQKHKSLIAERFELQNTIQELKDSLQQKEEQ--IQLFEKKNDEMQAETQDTLKQQKELNQ 3791 Query: 1260 QLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQ 1319 QL + K L Q++ + K+ + E Q+ + E+ +R LQE+ + Sbjct: 3792 QLETLKEK----LSHFQTNMTNPSEKLSSEEDAIGYQS-AKRYEDQIRELQEEIQKRTRE 3846 Query: 1320 IEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQE---QSILNIN---EE 1373 E LR+E E E + ++ Q + +++ +I +N E+ Sbjct: 3847 KEQLRTEKEIECIGLKQEMDRLQKLCDRLTEQEESQKQLKEVLEDHKNDAIQKLNKEKEK 3906 Query: 1374 NAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDE 1433 N ++KK ++ K + H S+ ++ Y Q+ E Sbjct: 3907 NKEMKKYLEEAHQEIEQLRKNRHEKHEKDGDNDHHQRKLSSKEDEEDAVY-----QKYKE 3961 Query: 1434 FENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQK----ESEIE-RVKLI 1488 E +++ +K++ED +SEL +++N + YE K + E+E +++L Sbjct: 3962 LEEKLTKILTEKKQLEDQNKSLQSELQ--NKSIYDNESFYEFQNKLLKSKQELEDKIELE 4019 Query: 1489 EELNVKITESVS 1500 ++L + + V+ Sbjct: 4020 QQLEICLERLVN 4031 Score = 136 bits (328), Expect = 6e-30 Identities = 272/1438 (18%), Positives = 594/1438 (41%), Gaps = 118/1438 (8%) Query: 212 EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271 ED K+ E + ++E ++L I + +++ ++ + L E E+ Sbjct: 720 EDNDAYYKKLFEEKVEGIQVLREENKQLQLQIHNLELKSYDKKKNLQKLYRIITEKDDEN 779 Query: 272 SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTE--IEEKGSLE--IANMTELTKK 327 KL +L+Q A QSIE +K + IE+ E I N+ Sbjct: 780 KKLKYQLQQKEQIDRESLNQ----AIQSIEEQLNQKMQLFIEDLAYKERIIENLQVNLFY 835 Query: 328 IELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWS 387 ++++ + Q N +N+ T S + +K L+S N + + Sbjct: 836 DNIIQNEKMRGEQINNVFQNQQETEQPISDKLIELRQKREDLLSILQNNNNYDQ----YG 891 Query: 388 QLSSETLNQDTDKKINKNEIAKLEMVIQSLNK-DLVDKEYVISEKDTXXXXXXXXXXGKD 446 + + N + K++ ++E IQ LN + K+ V ++ D K+ Sbjct: 892 NENEQQQNLNDIKELLGFIDQEIENEIQFLNNINQQQKQEVDNQNDQQVFAQDIPTSLKE 951 Query: 447 TLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLK 506 QLQ E QQ ++ S++ + + NE +V +QLK LN+E D N+ D E+++ Sbjct: 952 ----QLQKEIQQ-LKDQSILEL----QQYNE--EVIQQLKNILNEEELD-NIDDGFERIQ 999 Query: 507 SAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELH- 565 + Q E+D N I ++ KL +KQ D ++ KE+ +L ++ + Sbjct: 1000 IKLQHARQ---ELDQEQANKI-IELEKKLLIKQ-----DETGRLESQIKELQQLVKKQNK 1050 Query: 566 -HLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKF 624 + S K+ +++ N Y +E++ +K+I +LK + F Sbjct: 1051 QNSSPKIQNQQQDSRN-------YTVSAAVETEEDQKLINSLQNQIQKLKQEIQKANTDF 1103 Query: 625 DLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIEN 684 +++++ + E+ K + + Q+ V I++ LE+ I L+ K L E+ Sbjct: 1104 NIIKDDNKSFVSQIEILKKQNQLLETQNQNVQKNIQT--LEQTIKTLNEQNKSLQKEKES 1161 Query: 685 LKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAE---KISELLAKINH 741 + + +Q + E+ N+ + Y QE + +K K E K S A + Sbjct: 1162 ISKNLQQKTQNLAKSEDQVAQFKNENKLY-QEKCGILEKRIKELEETKKKSSTPSAGTSP 1220 Query: 742 EEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEES----IAVMEDRRYSLER 797 + K Q ++Q+ E ++ L +Y+ + EE +A +ED + LE Sbjct: 1221 NSKGKNQNTQQQQQQLQQYIKDCEQLKQLLIEYEQKFLEKEEDKSKLLAEIEDLKSKLEE 1280 Query: 798 KADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQI 857 + +E K L +L ++ + K++ ++E E +++ + Q Sbjct: 1281 AVTIIKQQEEENGKIKQNNQNSTSFLKEKLKEEIEQNL---KRVKDLEKEKEDIANEQQD 1337 Query: 858 LLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTL 917 +E QN SLS+ QQ + L+ K N + +YQ +++ + ++ I + + Sbjct: 1338 KIELYQN---SLSEKQQEIDELISKNNNLN---ELIDQYQREIKKCKEKMEEIKKMQEKV 1391 Query: 918 IVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQ----------EY 967 + ++K ++D + N IE D E+ E + + +L+ QLQ Sbjct: 1392 NLDQQKNMQDQLAQKNKLIEMMKNDSLDDKEEIELLKQEIEELKQQLQATQSKPLSSSRQ 1451 Query: 968 KNNIENLNMNVEELNKMNLELIDKHVQKQQ--TQSPDYTEQYINEINKLNALLKQKDE-- 1023 ++ + EE K+ + +K + +Q Q ++ E+ +L + L ++ Sbjct: 1452 ESQYKEFQQKEEEFKKLIKQQNEKIAKMEQDCLQKMEFEEEIARLQQELQSALDSHNDSG 1511 Query: 1024 --EIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEEL 1081 + +++Q IN+ + + + ++ +++ +EEE + + + +++ Sbjct: 1512 KKQNQSIDQIINDQDIDGLQNKRNQQNSFEDLQERVKELEEENNDLREIQNERDCLQQQI 1571 Query: 1082 QILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXX 1141 Q ++ + ++ +L+ T I K + + I+ + ++ ++ Sbjct: 1572 QEIIDKNKEETDQLQSTVRLLTQQIQKNQ-IDSEKIIQNLQNEIGSMTQFIKQQEQLIQQ 1630 Query: 1142 LKVQEEEEFIQERSVLQE----------QSAKLNTELQECYTKIIQLETLNTELTGHDVV 1191 + +++ I+ R +++E Q ++ +++E ++IQ++ N E + Sbjct: 1631 QNAEHDQKEIEFRQIIKEKDNYIFTQRDQIEQITDQIKEKNNQLIQMQE-NIEELKQNYE 1689 Query: 1192 NQEQIN--QLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREAD 1249 Q QIN Q+ + + + +NL E +S + +I EL Q L+Q+E + Sbjct: 1690 QQLQINNDQISNSNQNFQIQIENLQKLREEEEKYQNSNLSDLNNQIQEL-NQALSQKEEE 1748 Query: 1250 FQKTEHELRVQLSAFESKYEQL-LDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRN 1308 Q+ + V ++E+K ++L + +Q Q+E +I +++ L ++ D + + Sbjct: 1749 LQEINMKQSVIQQSYENKIKELEQNCLQIFEQKEELQI----RISQLDEEIADLKSVEKK 1804 Query: 1309 LQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSIL 1368 E+ + +E E+E++ + +++ + EQ I Sbjct: 1805 SFEEQTESTKSLENTIKELENQINQLNEQNKKQNEQLVQQNQIIAQQDEQINEQTEQ-IT 1863 Query: 1369 NINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIY---QKTHEYTI 1425 +N +N Q + +++ ++ EL Q++LK+ +I ++ + Sbjct: 1864 QLNLQNNQQNEQIIEQNQQIISQNDKIDQQNEEINELNEQIKLKNEQINKLDEQIKQLEE 1923 Query: 1426 TLTQRNDEFENVRQQLVEYEKRIED---LTYEKESELAILRLKMHENANHYETMQKESEI 1482 L Q N + + L EY+ ++ D L YE++ +L + + +N + ++ S I Sbjct: 1924 VLNQLNSQIKQKDLDL-EYKNQLFDNLKLQYEEQGQL-LHNHQEKLKSNTIKLDEQNSMI 1981 Query: 1483 -ERVKLIEELNVKITESV-----SLNKQ---VAELNKALEEEVAKTNEMQTALENQEIEI 1533 E +LI +L ++ S+ SLN+Q + +LN L + ++Q + + E Sbjct: 1982 EENQQLISQLRTQLENSLKENSHSLNEQENSINQLNCELLQMGQDKQQLQGLIHQLKEEN 2041 Query: 1534 VTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDL 1591 LN+++ N++ S I++ A + KQ QL +E + ++ + + +L Sbjct: 2042 SNLNEDLKQKLNIISESQQLIKEKSDIAEELKQNLTNQLQK--QQEYIQSIQQLQEEL 2097 Score = 135 bits (326), Expect = 1e-29 Identities = 254/1167 (21%), Positives = 511/1167 (43%), Gaps = 148/1167 (12%) Query: 523 NKN-MIKVKSNH-KLKLKQMQKTIDNFSK-VSDSNKEIVRLTEELHHLSQKVAELEEEKG 579 N+N M+K ++ + KLK+++ +K I + V D++ +L EE Q + E E ++ Sbjct: 689 NENRMLKQENEYLKLKIERCEKEIKEKKRIVEDNDAYYKKLFEEKVEGIQVLRE-ENKQL 747 Query: 580 NLQLH---LVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQK 636 LQ+H L YD + ++ +Y+ + E ++ E + L + ++ D L Q Sbjct: 748 QLQIHNLELKSYDKKKNLQK-LYRIITEKDD--ENKKLKYQLQQKEQIDRES----LNQA 800 Query: 637 YDEVEDKLADISQLQSDQVCSE---IKSVHLEEQIDALSASKKELALVIENLKLDKEQLY 693 +E++L QL + + + I+++ + D + ++K I N+ ++++ Sbjct: 801 IQSIEEQLNQKMQLFIEDLAYKERIIENLQVNLFYDNIIQNEKMRGEQINNVFQNQQETE 860 Query: 694 GTIKD----LENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQT 749 I D L +ED+++ LQN + + ++ + I ELL I+ E +++IQ Sbjct: 861 QPISDKLIELRQKREDLLSILQNNNNYDQYGNENEQQQNLNDIKELLGFIDQEIENEIQF 920 Query: 750 QFGIDAKIQ-------ERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQL 802 I+ + + ++ ++ ++I + L + + + + +++E ++Y+ E QL Sbjct: 921 LNNINQQQKQEVDNQNDQQVFAQDIPTSLKEQLQKEIQQLKDQSILELQQYN-EEVIQQL 979 Query: 803 GSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENK--ELQKKNQILLE 860 + L E E D+ R+ + + H R Q L+ E NK EL+KK I + Sbjct: 980 KNILNE------EELDNIDDGFERIQIKLQHAR----QELDQEQANKIIELEKKLLIKQD 1029 Query: 861 ENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLES---NLKRITHEHQTL 917 E L+ + ++QQ LV+K N+ ++ S K Q Q +D + + T E Q L Sbjct: 1030 ETGRLESQIKELQQ----LVKKQNK----QNSSPKIQNQQQDSRNYTVSAAVETEEDQKL 1081 Query: 918 IVQKKKEIEDLEIEF---NTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENL 974 I + +I+ L+ E NT D K + E + LE Q Q + NI+ L Sbjct: 1082 INSLQNQIQKLKQEIQKANTDFNIIKDDNKSFVSQIEILKKQNQLLETQNQNVQKNIQTL 1141 Query: 975 NMNVEELNKMNLEL------IDKHVQKQQTQ----SPDYTEQYINEINKLN----ALLKQ 1020 ++ LN+ N L I K++Q Q+TQ S D Q+ NE NKL +L++ Sbjct: 1142 EQTIKTLNEQNKSLQKEKESISKNLQ-QKTQNLAKSEDQVAQFKNE-NKLYQEKCGILEK 1199 Query: 1021 KDEEI------------------IALNQKINNAQVSYMSMVSDYE---SKLAQFTTKLEN 1059 + +E+ NQ Q + D E L ++ K Sbjct: 1200 RIKELEETKKKSSTPSAGTSPNSKGKNQNTQQQQQQLQQYIKDCEQLKQLLIEYEQKFLE 1259 Query: 1060 MEEEMQRVSKQLLDSKQHNEELQILVREQDDQ---IKELKETKLTFEMNIPKTE---GMI 1113 EE+ ++ ++ D K EE ++++Q+++ IK+ + +F K E + Sbjct: 1260 KEEDKSKLLAEIEDLKSKLEEAVTIIKQQEEENGKIKQNNQNSTSFLKEKLKEEIEQNLK 1319 Query: 1114 ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYT 1173 +E +D N K QE +E I + + L E + E+++C Sbjct: 1320 RVKDLEKEKEDIANEQQDKIELYQNSLSEKQQEIDELISKNNNLNELIDQYQREIKKCKE 1379 Query: 1174 KIIQLETLNTELTGHDVVN-QEQINQLKSKLEQLNTEN-------DNLLSTVAELRSSIS 1225 K+ +++ + ++ N Q+Q+ Q +E + ++ + L + EL+ + Sbjct: 1380 KMEEIKKMQEKVNLDQQKNMQDQLAQKNKLIEMMKNDSLDDKEEIELLKQEIEELKQQLQ 1439 Query: 1226 SA----------------VDQRGFEIAELWKQH---LAQREAD-FQKTEHELRVQLSAFE 1265 + Q+ E +L KQ +A+ E D QK E E +++ + Sbjct: 1440 ATQSKPLSSSRQESQYKEFQQKEEEFKKLIKQQNEKIAKMEQDCLQKMEFE--EEIARLQ 1497 Query: 1266 SKYEQLLDSVQSSTQEET---NKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEI 1322 + + LDS S +++ ++I+ + + LQNK ++++ +LQE+ ++ + Sbjct: 1498 QELQSALDSHNDSGKKQNQSIDQIINDQDIDGLQNK-RNQQNSFEDLQERVKELEEENND 1556 Query: 1323 LRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINE--ENAQLKKS 1380 LR EI++E+ L++ + Q +++ ++ + +N Q + Sbjct: 1557 LR-EIQNERDCLQQQIQEIIDKNKEETDQLQSTVRLLTQQIQKNQIDSEKIIQNLQNEIG 1615 Query: 1381 SXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQ 1440 S + +AE E+ + +K+ + Y T I Q D+ + Q Sbjct: 1616 SMTQFIKQQEQLIQQQNAEHDQKEIEFRQIIKEKDNYIFTQRDQI--EQITDQIKEKNNQ 1673 Query: 1441 LVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVS 1500 L++ ++ IE+L E +L I ++ N+N +Q E+ +++++ EE + + Sbjct: 1674 LIQMQENIEELKQNYEQQLQINNDQI-SNSNQNFQIQIEN-LQKLR-EEEEKYQNSNLSD 1730 Query: 1501 LNKQVAELNKAL---EEEVAKTNEMQTAL-ENQEIEIVTLND---EITNLQNMVRASSSK 1553 LN Q+ ELN+AL EEE+ + N Q+ + ++ E +I L +I + ++ S+ Sbjct: 1731 LNNQIQELNQALSQKEEELQEINMKQSVIQQSYENKIKELEQNCLQIFEQKEELQIRISQ 1790 Query: 1554 IQKHVS-FASDTKQGRDEQLDNTMNKE 1579 + + ++ S K+ +EQ ++T + E Sbjct: 1791 LDEEIADLKSVEKKSFEEQTESTKSLE 1817 Score = 109 bits (263), Expect = 5e-22 Identities = 206/970 (21%), Positives = 415/970 (42%), Gaps = 82/970 (8%) Query: 146 HLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXX 205 +L NT+ E DNAL + + +E TI L +KI QI N Sbjct: 3389 NLQNTLNECDNALIQERNERATVEETINLLNDKITNL-QIEREDNLEIIEKLKADLLQSQ 3447 Query: 206 XXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARF 265 K + + + A+ + Q + E D +I+ LE K + + Sbjct: 3448 PQKQNSSPIKLSLPQTSSQAGSSSAQKQQIDQLTFANAELLD-QINELELEIKEYQREKE 3506 Query: 266 EISLEHSKLAQELE--------QXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSL- 316 EI E+ KL +E+E Q + ++ + + E++ + +++ SL Sbjct: 3507 EILDENDKLTKEIELLKGLQGEQPVNRKVELIEDREIMEQELQQLNQEQQVQKQKRASLQ 3566 Query: 317 -EIANMTE-LTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKS 374 E++++ L + I +++ L +I K+L K ++ + A S++ S + Sbjct: 3567 NEMSDLKSILEQNIVVIQTLEEEIVNYKKKLAEKEESLQLKQVANDQNSERFSKIEEELD 3626 Query: 375 -GRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDT 433 ++ +K+ +QL + +D + N I +L +I+ D E + + K Sbjct: 3627 ISKHENQNLKNQITQLEQQLSEKDYHLEQQHNSICELSAMIEKFENQKSDAEVIENLKQM 3686 Query: 434 XXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEI 493 + +A E +Q I+ N E I+ +++ K + + Sbjct: 3687 HTDKMKKLVKEHNEALASKDKEIKQLTSLIKNINE-VNEEQNKTISSFEQKHKSLIAERF 3745 Query: 494 KDVN-VKDLIEKLKSAEEQIT---QLNDEIDAANKNMIKVKS--NHKL-----KLKQMQK 542 + N +++L + L+ EEQI + NDE+ A ++ +K + N +L KL Q Sbjct: 3746 ELQNTIQELKDSLQQKEEQIQLFEKKNDEMQAETQDTLKQQKELNQQLETLKEKLSHFQT 3805 Query: 543 TIDNFSKVSDSNKEIV------RLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIES 596 + N S+ S ++ + R +++ L +++ + EK L+ G E Sbjct: 3806 NMTNPSEKLSSEEDAIGYQSAKRYEDQIRELQEEIQKRTREKEQLRTEKEIECIGLKQEM 3865 Query: 597 DVYKKMIE-MENLAETRLKAISLLESQKFDLVQELHILQQKYDEV----EDKLADISQLQ 651 D +K+ + + E++ + +LE K D +Q+L+ ++K E+ E+ +I QL+ Sbjct: 3866 DRLQKLCDRLTEQEESQKQLKEVLEDHKNDAIQKLNKEKEKNKEMKKYLEEAHQEIEQLR 3925 Query: 652 SDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTI---KDLENDKEDIMN 708 ++ K + LS+ + E V + K +E+L + K LE+ + + + Sbjct: 3926 KNRHEKHEKDGDNDHHQRKLSSKEDEEDAVYQKYKELEEKLTKILTEKKQLEDQNKSLQS 3985 Query: 709 KLQNY-IQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENI 767 +LQN I +N + K+ K EL KI E+Q +I ++ + E +L + ++ Sbjct: 3986 ELQNKSIYDNESFYEFQNKLLKSK-QELEDKIELEQQLEIC----LERLVNEGELDLMDL 4040 Query: 768 ESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRL 827 + SRIC +L + + Q K+K S++ +DEL Sbjct: 4041 NN------SRICN-------------NLVKIQQNFKEFYQFKEKFGSKH---QDELKKIA 4078 Query: 828 AVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQ--ISLSDMQQHYNALVEKANR 885 V EKQ+ E++ + KE+ K + EEN++ + Q+ ++ + + Sbjct: 4079 QTYQSQLIVKEKQIKELQ-KYKEMYLKPVLNSEENRDPFNCTKIKIQQKELHSRPDTGRK 4137 Query: 886 TDLAESESTKY-QTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKK 944 ++++ + + + Q+ ++ES LK ++ I Q K+E+ED E N + R K Sbjct: 4138 SEMSNGQKDEQLEYQMLEIES-LKNENILLKSEIDQLKQELEDNEQIQNNFMAEQRRKNK 4196 Query: 945 VLNEKYEKNIEYVTQLEAQLQEYKN--NIENLNMNVEELNKMNLELIDKHVQKQQTQSPD 1002 L EK +K E ++Q Q + N N+ + N+N E+ KM ++ K QQ QS Sbjct: 4197 ELQEKEQKIQELISQQNQQKIQSSNRLNMSSSNLN-SEVTKMRQQMEHKDKLIQQLQSQI 4255 Query: 1003 YTEQYINEINKLNALLKQKDEEII-ALNQKINNAQVSYMSMVSDYESKLAQFTTKLEN-M 1060 Q + + L AL + ++ + ++KI+ SY++++ + + +++ K +N + Sbjct: 4256 NVTQDSSIKHSLKALFPTYIDSLLNSKDKKISQENDSYLTLILN----MLEYSEKEKNEI 4311 Query: 1061 EEEMQRVSKQ 1070 +++M + Q Sbjct: 4312 KQKMDKAKNQ 4321 Score = 94.7 bits (225), Expect = 2e-17 Identities = 137/692 (19%), Positives = 288/692 (41%), Gaps = 54/692 (7%) Query: 918 IVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMN 977 I +KK+ +ED + + E + +VL E+ ++ + LE + + K N++ L Sbjct: 712 IKEKKRIVEDNDAYYKKLFEEKVEGIQVLREENKQLQLQIHNLELKSYDKKKNLQKLYRI 771 Query: 978 VEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQV 1037 + E + N +L + QK+Q + + +LN ++ E++ + I N QV Sbjct: 772 ITEKDDENKKLKYQLQQKEQIDRESLNQAIQSIEEQLNQKMQLFIEDLAYKERIIENLQV 831 Query: 1038 S--YMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKEL 1095 + Y +++ + + + Q +N +E Q +S +L++ +Q E+L +++ ++ + Sbjct: 832 NLFYDNIIQNEKMRGEQINNVFQNQQETEQPISDKLIELRQKREDLLSILQNNNNYDQYG 891 Query: 1096 KETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERS 1155 E + +N K I IE NN++ Q++++ + ++ Sbjct: 892 NENEQQQNLNDIKELLGFIDQEIENEIQFLNNIN---------------QQQKQEVDNQN 936 Query: 1156 VLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKL--EQLNTENDNL 1213 Q + + T L+E K IQ + + + N+E I QLK+ L E+L+ +D Sbjct: 937 DQQVFAQDIPTSLKEQLQKEIQ-QLKDQSILELQQYNEEVIQQLKNILNEEELDNIDDGF 995 Query: 1214 LSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLD 1273 +L+ + ++ +I EL K+ L +++ + +Q + + Sbjct: 996 ERIQIKLQHARQELDQEQANKIIELEKKLLIKQDETGRLESQIKELQQLVKKQNKQNSSP 1055 Query: 1274 SVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVA 1333 +Q+ Q+ N V+ T KL + L+N +K I + + I+D+ + Sbjct: 1056 KIQNQQQDSRNYTVSAAVETEEDQKLINS---LQNQIQKLKQEIQKANTDFNIIKDDNKS 1112 Query: 1334 FXXXXXXXXXXXXXXXXDLRTENQSYK---QMQEQSILNINEENAQLKKSSXXXXXXXXX 1390 F L T+NQ+ + Q EQ+I +NE+N L+K Sbjct: 1113 FVSQIEILKKQNQL----LETQNQNVQKNIQTLEQTIKTLNEQNKSLQKEKESISKNLQQ 1168 Query: 1391 XXXRVNDAEAKVLELTHQ----------LELKDSEIYQKTHEYTITLTQRNDEFENVRQQ 1440 + +E +V + ++ LE + E+ + + + + + Q Sbjct: 1169 KTQNLAKSEDQVAQFKNENKLYQEKCGILEKRIKELEETKKKSSTPSAGTSPNSKGKNQN 1228 Query: 1441 LVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKL---IEELNVKITE 1497 + +++++ Y K+ E ++ + YE E E ++ KL IE+L K+ E Sbjct: 1229 TQQQQQQLQQ--YIKDCE------QLKQLLIEYEQKFLEKEEDKSKLLAEIEDLKSKLEE 1280 Query: 1498 SVSLNKQVAELNKALEEEVAKTNEMQTALENQEIE--IVTLNDEITNLQNMVRASSSKIQ 1555 +V++ KQ E N +++ + +EIE + + D +++ KI+ Sbjct: 1281 AVTIIKQQEEENGKIKQNNQNSTSFLKEKLKEEIEQNLKRVKDLEKEKEDIANEQQDKIE 1340 Query: 1556 KHVSFASDTKQGRDEQLDNTMN-KELLDAVPR 1586 + + S+ +Q DE + N EL+D R Sbjct: 1341 LYQNSLSEKQQEIDELISKNNNLNELIDQYQR 1372 Score = 76.6 bits (180), Expect = 5e-12 Identities = 186/1005 (18%), Positives = 404/1005 (40%), Gaps = 84/1005 (8%) Query: 147 LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXX 206 L ++++ +L K + + + + + + +++ + +N+ + Sbjct: 3235 LQEELQKQIEGNHILSQKQQEEKDLVSENSQNLQQQNLDLHKENEESKAKIQQMKEKLSQ 3294 Query: 207 XXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFE 266 E K QE M E + E + K+I+ V+I LE + Sbjct: 3295 LEEQIEKVNDDKQKSQEENEKMRIEKETEIEEKEKEIQKLKVQIQDLEGVMEEQTQQIQT 3354 Query: 267 ISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTK 326 ++E K ++L++ + KQ E + + E + I E Sbjct: 3355 ANVEVEKFKKDLDERYNQIAFLED----ILKQLEEEKNNLQNTLNECDNALIQERNERAT 3410 Query: 327 KIELLEHLNCQI------RQTNKELENKLATMGTES---KAVSSPSKKGSPLISRKSGRN 377 E + LN +I R+ N E+ KL +S K SSP K P S ++G + Sbjct: 3411 VEETINLLNDKITNLQIEREDNLEIIEKLKADLLQSQPQKQNSSPIKLSLPQTSSQAGSS 3470 Query: 378 TASKMK-SPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVIS--EKDTX 434 +A K + + ++E L+Q + ++ E + + I N L + ++ + + Sbjct: 3471 SAQKQQIDQLTFANAELLDQINELELEIKEYQREKEEILDENDKLTKEIELLKGLQGEQP 3530 Query: 435 XXXXXXXXXGKDTLIAQLQ-LEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEI 493 ++ + +LQ L +Q ++ + D+ I + + Q L +EI Sbjct: 3531 VNRKVELIEDREIMEQELQQLNQEQQVQKQKRASLQNEMSDLKSILEQNIVVIQTLEEEI 3590 Query: 494 KDVNVKDLIEKLKSAE----------EQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKT 543 + K L EK +S + E+ +++ +E+D + +K+ +Q+ + Sbjct: 3591 VNYK-KKLAEKEESLQLKQVANDQNSERFSKIEEELDISKHENQNLKNQITQLEQQLSEK 3649 Query: 544 IDNFSKVSDSNKEIVRLTEELHHL---SQKVAELEEEKGNLQLHLVDYDSGRMIESDVYK 600 + + +S E+ + E+ + ++ + L++ + LV + + D Sbjct: 3650 DYHLEQQHNSICELSAMIEKFENQKSDAEVIENLKQMHTDKMKKLVKEHNEALASKDKEI 3709 Query: 601 KMI-----EMENLAETRLKAISLLE-------SQKFDL---VQELH-ILQQKYDEVE--D 642 K + + + E + K IS E +++F+L +QEL LQQK ++++ + Sbjct: 3710 KQLTSLIKNINEVNEEQNKTISSFEQKHKSLIAERFELQNTIQELKDSLQQKEEQIQLFE 3769 Query: 643 KLADISQLQSDQVCSEIKSVH--LEEQIDALSASKKELALVIENLKLDKEQL-YGTIKDL 699 K D Q ++ + K ++ LE + LS + + E L +++ + Y + K Sbjct: 3770 KKNDEMQAETQDTLKQQKELNQQLETLKEKLSHFQTNMTNPSEKLSSEEDAIGYQSAKRY 3829 Query: 700 ENDKEDIMNKLQNYIQENMDLTDKLE------KMSAEKISELLAKINHEEQSKIQTQFGI 753 E+ ++ ++Q +E L + E K +++ +L ++ +E+S+ Q + + Sbjct: 3830 EDQIRELQEEIQKRTREKEQLRTEKEIECIGLKQEMDRLQKLCDRLTEQEESQKQLKEVL 3889 Query: 754 DAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAY 813 + ++ I+ + E K K LEE+ +E R + K ++ G ++K Sbjct: 3890 E---DHKNDAIQKLNKEKEKNKEMKKYLEEAHQEIEQLRKNRHEKHEKDGDNDHHQRKLS 3946 Query: 814 SEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENK----ELQKKNQILLEENQNLQISL 869 S+ +ED + + L + + + ++E +NK ELQ K+ E Q L Sbjct: 3947 SKED-EEDAVYQKYKELEEKLTKILTEKKQLEDQNKSLQSELQNKSIYDNESFYEFQNKL 4005 Query: 870 SDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLE 929 +Q +E + ++ E + +L ++ N RI + + I Q KE + Sbjct: 4006 LKSKQELEDKIELEQQLEIC-LERLVNEGELDLMDLNNSRICN-NLVKIQQNFKEFYQFK 4063 Query: 930 IEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELI 989 +F ++ + + K + + Y+ + + +LQ+YK +N EE N+ Sbjct: 4064 EKFGSKHQDEL---KKIAQTYQSQLIVKEKQIKELQKYKEMYLKPVLNSEE-NRDPFNCT 4119 Query: 990 DKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEI---IALNQKINNAQVSYMSMVSDY 1046 +Q+++ S T + N QKDE++ + + + N + S + Sbjct: 4120 KIKIQQKELHSRPDTGRKSEMSNG------QKDEQLEYQMLEIESLKNENILLKSEIDQL 4173 Query: 1047 ESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQ 1091 + +L N E +R +K+L + +Q ++Q L+ +Q+ Q Sbjct: 4174 KQELEDNEQIQNNFMAEQRRKNKELQEKEQ---KIQELISQQNQQ 4215 >UniRef50_Q54G05 Cluster: Putative uncharacterized protein; n=1; Dictyostelium discoideum AX4|Rep: Putative uncharacterized protein - Dictyostelium discoideum AX4 Length = 1492 Score = 195 bits (475), Expect = 1e-47 Identities = 273/1356 (20%), Positives = 592/1356 (43%), Gaps = 99/1356 (7%) Query: 147 LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKN----KATTXXXXXXXX 202 L IK KDN + L+ K+K + + +++ EK++ E + + TT Sbjct: 123 LDGLIKTKDNDIIKLREKIKHLNEKHQESEKRYQEKEKKFEEQRTIEIQETTKKEQEIKS 182 Query: 203 XXXXXXXXXEDTK---QQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKL 259 E K +Q+ K+ + E E + +LK + K I +E N Sbjct: 183 LTLQLSSKDESMKSLEKQVEKLVDIEHRSEIEQTKKDNEILK-LTEKIKEIQLIENLNST 241 Query: 260 LEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEE-KTEIEEKGSLEI 318 ++ ++ ++ K QE KQ E + + EI++K + E+ Sbjct: 242 NDSKVNQLLEDNIKRLQESLNEIKDENNDLQSLIDTQKQQFEKRINQYQLEIQDKEN-EL 300 Query: 319 ANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNT 378 M + + + ++ ++Q+ +LEN T+ + V++ + ++ K Sbjct: 301 NEMNQ--QSLSQVKSFQQSLQQSQLDLENDKNQFSTKLQLVNNEIQSLKSIVDDK----- 353 Query: 379 ASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXX 438 +++ +QL+ + D N I +L I ++ L +K+ I E Sbjct: 354 LKEIQLKDNQLTQLNQQHEIDNNKNNQMILELNDNISKISNQLNEKDNKIQELSKQSIDK 413 Query: 439 XXXXXGKDTLIAQLQLE----HQQHMEGPSLIHVGTN--TEDVNEIAKVQEQLKQELNDE 492 + QLQL+ + +E + I+ +N + N+I ++ +L ++ N Sbjct: 414 QKEIENSTSSSDQLQLKLNDISNELLEKLNDINQLSNKLQDKENQILEINNKLNEKENQL 473 Query: 493 I-KDVNVKDLIEKLKSAEEQ----ITQLNDEIDAANKNMI---KVKSNHKLKLKQMQKTI 544 I KD + LIE +S+ ++ + QL+DE+ ++ ++ V + + L + Q I Sbjct: 474 ISKDNQLNQLIENNESSSDELKLKLNQLSDELQEKDEKLLNNQSVINELQSNLNENQNKI 533 Query: 545 DNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSG-RMIESDVYKKMI 603 + + + S+ + ++L +L+ LS K+ E +E+ +L+ +++ D ++ ++ +K Sbjct: 534 NELIENNQSSSDELKL--KLNQLSDKLQEKDEKLKSLESSIIERDEKIDQLQDNLNEKQD 591 Query: 604 EMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVH 663 ++ L E + L+S+ L+Q LQ+K +++ + + I++LQS+ ++ K Sbjct: 592 KINELVENNESSSDELQSK---LIQLSDQLQEKDEKLLNNQSIINELQSNLNENQNK--- 645 Query: 664 LEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDK 723 + E I+ +S EL + L + + ++ LE + +KL IQ N ++ Sbjct: 646 INELIENNQSSSDELNSKLIKLSDELKDKNENVRSLETSIIENQDKLDQLIQSNQVTVNE 705 Query: 724 LEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEE 783 L+ EK + I + + S + Q ++ K E + IEN +S + +S++ + Sbjct: 706 LQSKLNEKEININQLIENNQSSLDELQSKLNEKQNEINQLIENNQSSSDELQSKLNEKHQ 765 Query: 784 SIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRL--AVLMDHDRVV---- 837 I+ ++ + L + LQ K S+ ++DE + L ++ + +++V Sbjct: 766 EISELQSKLNELIENNESSSDELQSKLIQLSDELKEKDEKLKSLDSIIIENQEKLVQLTK 825 Query: 838 --EKQLLEIEHENKELQKKNQILLEENQN----LQISLSDMQQHYNALVE-KANRTDLAE 890 + L E++ + E Q + L+E NQ+ LQ L++ Q N L+E + +D + Sbjct: 826 SNQDSLDELQSKLNEKQNEINELIENNQSSSNELQSKLNEKQNEINLLIENNQSSSDELQ 885 Query: 891 SESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKY 950 S+ + ++ +L+S L ++ L+ + ++L+ + Q+ +++K+ + + Sbjct: 886 SKLNEKHQEINELQSKLNEKQNKINELVENNESSSDELQSKL-IQLSDQLQEKENQLKSF 944 Query: 951 EKNI----EYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQ 1006 E +I E + QL+++L E +N I+ + N N+ +L+ + ++ ++Q + E Sbjct: 945 ESSIIERDEKLNQLQSKLNEKQNEIDQITEN----NQSSLDELQSNLNEKQNEINQLIEN 1000 Query: 1007 YINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQR 1066 + +++L + L +K EI + KIN + S+ D +SK +LE ++ Sbjct: 1001 NQSSLDELQSKLNEKLNEINEKDNKINELIQTNESLSKDQQSKFENLEQELEEKNNKILD 1060 Query: 1067 VSKQLLD-----SKQHNE--ELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIE 1119 ++ Q++D S++ NE +LQ+ + E+D +I+ + + + E I Sbjct: 1061 LNSQIIDVNHQFSEKENELNQLQLKLIEKDQEIENQNNKIIDINNQLNEKE-----KEIN 1115 Query: 1120 PMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLE 1179 +D+ NN + L+ E E E+ + E++ +N EL+E +++ Sbjct: 1116 INNDNDNNNEENIQLIEELKEKLQ-DLENELNLEKDTVNEKNDDIN-ELKE------EIK 1167 Query: 1180 TLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELW 1239 ++ +L+ + E IN L ++N + D L+ ++ E ++ ++++ EI L Sbjct: 1168 LISEKLSEKEQELNEMINDYDESLNEINDQKD-LVKSLNERLTNAHLKINEKDNEIHSLS 1226 Query: 1240 KQHLAQREADF-----QKTEHE-LRVQLSAFESKYE-QLLDSVQ----SSTQEETNKIVT 1288 K+ + ++ Q +E + L ++ S S E QL +S + SS+ + ++++ Sbjct: 1227 KEGFNEIQSQLNLITNQLSEKDNLLIEKSQIISDLELQLRESYKERSSSSSLHQQQQMIS 1286 Query: 1289 MEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXX 1348 + S + +KEE + L+EK + Q++ L + K Sbjct: 1287 PDLSNSNDELIVEKEEIINELKEKNQQLEQQLQDLCQQFNKNKQENELKCQQLEEENDGW 1346 Query: 1349 XXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQ 1408 ++ T NQ K + + +E QL S + D K+ L +Q Sbjct: 1347 KNEIDTLNQRLKTQSLNTSPDSSELQQQLDIIS-NQELNIKQLEKELQDKSGKIDNLEYQ 1405 Query: 1409 LELKDS----EIYQKTHEYTITLTQRNDEFENVRQQ 1440 +E + +I QKT+E + L E + +R++ Sbjct: 1406 VEEMNKQYHIDINQKTNESSEKLQSIQLEIDTIREK 1441 Score = 182 bits (443), Expect = 7e-44 Identities = 254/1282 (19%), Positives = 550/1282 (42%), Gaps = 81/1282 (6%) Query: 305 EEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATM-GTESKAVSSPS 363 E++ + EE+ ++EI T+ ++I+ L ++ K LE ++ + E ++ + Sbjct: 157 EKEKKFEEQRTIEIQETTKKEQEIKSLTLQLSSKDESMKSLEKQVEKLVDIEHRSEIEQT 216 Query: 364 KKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVD 423 KK + ++ K+K QL E LN D K+N+ ++ + +SLN+ + Sbjct: 217 KKDNEILK------LTEKIKE--IQLI-ENLNSTNDSKVNQLLEDNIKRLQESLNEIKDE 267 Query: 424 KEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQE 483 + S DT + I Q QLE Q + + N + ++++ Q+ Sbjct: 268 NNDLQSLIDTQKQQF-------EKRINQYQLEIQDKENELNEM----NQQSLSQVKSFQQ 316 Query: 484 QLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKT 543 L+Q D D N KL+ +I L +D K I++K N +L Q Q Sbjct: 317 SLQQSQLDLENDKN--QFSTKLQLVNNEIQSLKSIVDDKLKE-IQLKDNQLTQLNQ-QHE 372 Query: 544 IDNFSK---VSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYK 600 IDN + + N I +++ +L+ K+ EL ++ + Q + + S + Sbjct: 373 IDNNKNNQMILELNDNISKISNQLNEKDNKIQELSKQSIDKQKEIENSTSS---SDQLQL 429 Query: 601 KMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLAD----ISQL-QSDQV 655 K+ ++ N +L I+ L ++ D ++ + K +E E++L ++QL ++++ Sbjct: 430 KLNDISNELLEKLNDINQLSNKLQDKENQILEINNKLNEKENQLISKDNQLNQLIENNES 489 Query: 656 CSEIKSVHLEEQIDALSASKKELA---LVIENLKLDKEQLYGTIKDLENDKEDIMNKLQN 712 S+ + L + D L ++L VI L+ + + I +L + + ++L+ Sbjct: 490 SSDELKLKLNQLSDELQEKDEKLLNNQSVINELQSNLNENQNKINELIENNQSSSDELKL 549 Query: 713 YIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELS 772 + + L+DKL++ EK+ L + I ++ Q Q ++ K + + +EN ES Sbjct: 550 KLNQ---LSDKLQEKD-EKLKSLESSIIERDEKIDQLQDNLNEKQDKINELVENNESSSD 605 Query: 773 KYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYT----IQEDELVNRLA 828 + +S++ +L + + +++ + + ++L S L E Q +E DEL ++L Sbjct: 606 ELQSKLIQLSDQLQEKDEKLLNNQSIINELQSNLNENQNKINELIENNQSSSDELNSKLI 665 Query: 829 VLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQ----NLQISLSDMQQHYNALVEKAN 884 L D + + + +E E Q K L++ NQ LQ L++ + + N L+E N Sbjct: 666 KLSDELKDKNENVRSLETSIIENQDKLDQLIQSNQVTVNELQSKLNEKEININQLIEN-N 724 Query: 885 RTDLAESES--TKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRD 942 ++ L E +S + Q ++ L N + + E Q+ + +K +EI +L+ + N IE+ Sbjct: 725 QSSLDELQSKLNEKQNEINQLIENNQSSSDELQSKLNEKHQEISELQSKLNELIENNESS 784 Query: 943 KKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPD 1002 L K + + + + + +L+ + I + +L K N + +D+ K + + Sbjct: 785 SDELQSKLIQLSDELKEKDEKLKSLDSIIIENQEKLVQLTKSNQDSLDELQSKLNEKQNE 844 Query: 1003 YTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEE 1062 E N + N L + +E+ +N I N Q S + S K + + E Sbjct: 845 INELIENNQSSSNELQSKLNEKQNEINLLIENNQSSSDELQSKLNEKHQEINELQSKLNE 904 Query: 1063 EMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMS 1122 + ++++ + +++ ++ELQ + + DQ++E + +FE +I + + ++ ++ Sbjct: 905 KQNKINELVENNESSSDELQSKLIQLSDQLQEKENQLKSFESSIIERDEK-LNQLQSKLN 963 Query: 1123 DDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLN 1182 + N +D L+ E+ + +++ + L+ + K+ ++ + Sbjct: 964 EKQNEIDQITENNQSSLDELQSNLNEKQNEINQLIENNQSSLDELQSKLNEKLNEINEKD 1023 Query: 1183 TELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQH 1242 ++ N+ +SK E L E + + + +L S I Q + EL + Sbjct: 1024 NKINELIQTNESLSKDQQSKFENLEQELEEKNNKILDLNSQIIDVNHQFSEKENELNQLQ 1083 Query: 1243 LAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDK 1302 L E D Q+ E++ ++ ++ + + + + N ++ + L+ KLQD Sbjct: 1084 LKLIEKD-QEIENQ-NNKIIDINNQLNEKEKEININNDNDNNNEENIQLIEELKEKLQDL 1141 Query: 1303 EEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQM 1362 E L NL++ D +N+ +E+++E L + Q +M Sbjct: 1142 ENEL-NLEK---DTVNEKNDDINELKEE--------------IKLISEKLSEKEQELNEM 1183 Query: 1363 QEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHE 1422 ++NE N Q K ++N+ + ++ L+ + +EI + + Sbjct: 1184 INDYDESLNEINDQ-KDLVKSLNERLTNAHLKINEKDNEIHSLSKE---GFNEIQSQLNL 1239 Query: 1423 YTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEI 1482 T L+++++ Q + + E ++ + +Y++ S + L + + E + Sbjct: 1240 ITNQLSEKDNLLIEKSQIISDLELQLRE-SYKERSSSSSLHQQQQMISPDLSNSNDELIV 1298 Query: 1483 ERVKLIEELNVKITE-SVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEIT 1541 E+ ++I EL K + L + NK +E K +++ + + EI TLN + Sbjct: 1299 EKEEIINELKEKNQQLEQQLQDLCQQFNKNKQENELKCQQLEEENDGWKNEIDTLNQRLK 1358 Query: 1542 NLQNMVRASSSKIQKHVSFASD 1563 SS++Q+ + S+ Sbjct: 1359 TQSLNTSPDSSELQQQLDIISN 1380 Score = 179 bits (436), Expect = 5e-43 Identities = 256/1187 (21%), Positives = 520/1187 (43%), Gaps = 93/1187 (7%) Query: 459 HMEGPSLIHVGTNTEDVNEIAKVQEQLKQELN-DEIKDVNVKDLIEKLKSAEEQITQLND 517 H+E P +++ D EI E +K + EI V+ L +K+ + I +L + Sbjct: 81 HVEVPGRVYILRAKNDT-EINYWIEGIKDAIKYHEINSSQVQVLDGLIKTKDNDIIKLRE 139 Query: 518 EIDAANKNMIKVKSNHKLKLKQM--QKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELE 575 +I N+ + + ++ K K+ Q+TI+ + + +EI LT +L + + LE Sbjct: 140 KIKHLNEKHQESEKRYQEKEKKFEEQRTIE-IQETTKKEQEIKSLTLQLSSKDESMKSLE 198 Query: 576 EEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLES------QKFDLVQE 629 ++ L VD + IE KK E+ L E ++K I L+E+ K + + E Sbjct: 199 KQVEKL----VDIEHRSEIEQT--KKDNEILKLTE-KIKEIQLIENLNSTNDSKVNQLLE 251 Query: 630 LHI--LQQKYDEVEDKLADISQL---QSDQVCSEIKSVHLEEQIDALSASKKELALVIEN 684 +I LQ+ +E++D+ D+ L Q Q I LE Q D + + + Sbjct: 252 DNIKRLQESLNEIKDENNDLQSLIDTQKQQFEKRINQYQLEIQ-DKENELNEMNQQSLSQ 310 Query: 685 LKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQ 744 +K ++ L + DLENDK KLQ E L+ + +K+ E+ K N + Sbjct: 311 VKSFQQSLQQSQLDLENDKNQFSTKLQLVNNE----IQSLKSIVDDKLKEIQLKDN--QL 364 Query: 745 SKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGS 804 +++ Q ID + + I + +SK +++ + I + + +++ + S Sbjct: 365 TQLNQQHEIDNN--KNNQMILELNDNISKISNQLNEKDNKIQELSKQSIDKQKEIENSTS 422 Query: 805 YLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQN 864 + Q ++ + + E +N + L + + E Q+LEI NK +K+NQ++ ++NQ Sbjct: 423 SSDQLQLKLNDISNELLEKLNDINQLSNKLQDKENQILEIN--NKLNEKENQLISKDNQL 480 Query: 865 LQISLSDMQQHYNALVEKANR-TDLAESESTKY---QTQLRDLESNLKRITHEHQTLIVQ 920 Q+ + + + + L K N+ +D + + K Q+ + +L+SNL ++ LI Sbjct: 481 NQL-IENNESSSDELKLKLNQLSDELQEKDEKLLNNQSVINELQSNLNENQNKINELIEN 539 Query: 921 KKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNI----EYVTQLEAQLQEYKNNIENLNM 976 + ++L+++ N Q+ +++K + E +I E + QL+ L E ++ I L Sbjct: 540 NQSSSDELKLKLN-QLSDKLQEKDEKLKSLESSIIERDEKIDQLQDNLNEKQDKINEL-- 596 Query: 977 NVEELNKMNLELIDKHVQ-KQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNA 1035 VE + EL K +Q Q Q D E+ +N + +N L +E +N+ I N Sbjct: 597 -VENNESSSDELQSKLIQLSDQLQEKD--EKLLNNQSIINELQSNLNENQNKINELIENN 653 Query: 1036 QVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEEL----QILVREQDDQ 1091 Q S + SKL + + +L++ E ++ + +++++ ++L Q+ V E + Sbjct: 654 Q----SSSDELNSKLIKLSDELKDKNENVRSLETSIIENQDKLDQLIQSNQVTVNELQSK 709 Query: 1092 IKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFI 1151 + E KE + + ++ + S + ++ N + ++ +E Sbjct: 710 LNE-KEININQLIENNQSSLDELQSKLNEKQNEINQLIENNQSSSDELQSKLNEKHQEIS 768 Query: 1152 QERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTEND 1211 + +S L E + E +K+IQL + EL +E+ +LKS L+ + EN Sbjct: 769 ELQSKLNELIENNESSSDELQSKLIQL---SDEL-------KEKDEKLKS-LDSIIIENQ 817 Query: 1212 NLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQL 1271 L +L S ++D+ ++ E + + + + Q + +EL+ +L+ +++ L Sbjct: 818 EKL---VQLTKSNQDSLDELQSKLNEK-QNEINELIENNQSSSNELQSKLNEKQNEINLL 873 Query: 1272 LDSVQSSTQEETNKIVTMEQ-VTSLQNKLQDKEEHLRNL---QEKYADVIN----QIEIL 1323 +++ QSS+ E +K+ Q + LQ+KL +K+ + L E +D + Q+ Sbjct: 874 IENNQSSSDELQSKLNEKHQEINELQSKLNEKQNKINELVENNESSSDELQSKLIQLSDQ 933 Query: 1324 RSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXX 1383 E E++ +F L + Q+ E + +++E + L + Sbjct: 934 LQEKENQLKSFESSIIERDEKLNQLQSKLNEKQNEIDQITENNQSSLDELQSNLNEKQNE 993 Query: 1384 XXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVE 1443 +++ ++K+ E +++ KD++I + + +FEN+ Q+L E Sbjct: 994 INQLIENNQSSLDELQSKLNEKLNEINEKDNKINELIQTNESLSKDQQSKFENLEQELEE 1053 Query: 1444 YEKRIEDLTY----------EKESELAILRLKMHENANHYETMQKESEIERVKLIEELNV 1493 +I DL EKE+EL L+LK+ E E Q I+ + E Sbjct: 1054 KNNKILDLNSQIIDVNHQFSEKENELNQLQLKLIEKDQEIEN-QNNKIIDINNQLNEKEK 1112 Query: 1494 KITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSK 1553 +I + + E + +EE K +++ L ++ + ND+I L+ ++ S K Sbjct: 1113 EININNDNDNNNEENIQLIEELKEKLQDLENELNLEKDTVNEKNDDINELKEEIKLISEK 1172 Query: 1554 IQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDLAMYMLHQRD 1600 + + ++ DE L+ +++ L L A ++++D Sbjct: 1173 LSEKEQELNEMINDYDESLNEINDQKDLVKSLNERLTNAHLKINEKD 1219 Score = 130 bits (313), Expect = 4e-28 Identities = 202/1050 (19%), Positives = 471/1050 (44%), Gaps = 95/1050 (9%) Query: 96 NTLKQKEILMEKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKD 155 N K L EK + +ELSK+S + +L D+ SN + EK Sbjct: 388 NISKISNQLNEKDNKIQELSKQSIDK--QKEIENSTSSSDQLQLKLNDI---SNELLEKL 442 Query: 156 NALSVLQVKMKIMETTILDLQEKINEKD-QIIEAKNKATTXXXXXXXXXXXXXXXXXEDT 214 N ++ L K++ E IL++ K+NEK+ Q+I N+ ++ Sbjct: 443 NDINQLSNKLQDKENQILEINNKLNEKENQLISKDNQLN-------------QLIENNES 489 Query: 215 KQQMTKMQENFIAMEAEWKDEK----QRLLKDIESK-DVRISSLEEANKLLEAARFEISL 269 K++ N ++ E + KDEK Q ++ +++S + + + E + +++ E+ L Sbjct: 490 SSDELKLKLNQLSDELQEKDEKLLNNQSVINELQSNLNENQNKINELIENNQSSSDELKL 549 Query: 270 EHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIE 329 + ++L+ +L++ + I+ + E ++K + + N + +++ Sbjct: 550 KLNQLSDKLQEKDEKLKSLESSIIE-RDEKIDQLQDNLNEKQDKINELVENNESSSDELQ 608 Query: 330 -LLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQ 388 L L+ Q+++ +++L N + + ++ K + LI ++ ++++ ++ S + Sbjct: 609 SKLIQLSDQLQEKDEKLLNNQSIINELQSNLNENQNKINELI--ENNQSSSDELNSKLIK 666 Query: 389 LSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTL 448 LS E +D ++ + E + +E N+D +D+ +I K+ Sbjct: 667 LSDEL--KDKNENVRSLETSIIE------NQDKLDQ--LIQSNQVTVNELQSKLNEKEIN 716 Query: 449 IAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEI--KDVNVKDLIEKLK 506 I QL +E+ Q + ++N++ + + EL ++ K + +L KL Sbjct: 717 INQL-IENNQSSLDELQSKLNEKQNEINQLIENNQSSSDELQSKLNEKHQEISELQSKLN 775 Query: 507 SAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTE-ELH 565 E +DE+ + +I++ K K +++ K++D S + ++ +++V+LT+ Sbjct: 776 ELIENNESSSDELQS---KLIQLSDELKEKDEKL-KSLD--SIIIENQEKLVQLTKSNQD 829 Query: 566 HLSQKVAELEEEKGNL-QLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKF 624 L + ++L E++ + +L + S ++S + +K E+ L E + L+S+ Sbjct: 830 SLDELQSKLNEKQNEINELIENNQSSSNELQSKLNEKQNEINLLIENNQSSSDELQSKLN 889 Query: 625 DLVQELHILQQKYDEVEDKLADI---SQLQSDQVCSEIKSV-----HLEEQIDALSASKK 676 + QE++ LQ K +E ++K+ ++ ++ SD++ S++ + E Q+ + +S Sbjct: 890 EKHQEINELQSKLNEKQNKINELVENNESSSDELQSKLIQLSDQLQEKENQLKSFESSII 949 Query: 677 ELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELL 736 E + L+ + I + + + +++LQ+ + E + ++L + + + EL Sbjct: 950 ERDEKLNQLQSKLNEKQNEIDQITENNQSSLDELQSNLNEKQNEINQLIENNQSSLDELQ 1009 Query: 737 AKIN------HEEQSKIQTQFGIDAKI-QERDLYIENIESELSKYKSRICRLEESIAVME 789 +K+N +E+ +KI + + +++ EN+E EL + ++I L I + Sbjct: 1010 SKLNEKLNEINEKDNKINELIQTNESLSKDQQSKFENLEQELEEKNNKILDLNSQIIDVN 1069 Query: 790 DRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENK 849 + E + +QL L EK QE E N + +++ +++ + I ++N Sbjct: 1070 HQFSEKENELNQLQLKLIEKD--------QEIENQNNKIIDINNQLNEKEKEININNDND 1121 Query: 850 ELQKKNQILLEE-NQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLK 908 ++N L+EE + LQ +++ + + EK + + + E +L + E L Sbjct: 1122 NNNEENIQLIEELKEKLQDLENELNLEKDTVNEKNDDINELKEEIKLISEKLSEKEQELN 1181 Query: 909 RITHEHQTLIVQKKKEIEDLEIEFNTQIESA-IRDKKVLNEKYEKNIEYVTQLEAQLQEY 967 + +++ + + + +DL N ++ +A ++ + NE + + E ++++QL Sbjct: 1182 EMINDYDESL-NEINDQKDLVKSLNERLTNAHLKINEKDNEIHSLSKEGFNEIQSQLNLI 1240 Query: 968 KNNI-ENLNMNVEE---LNKMNLELIDKHVQKQQTQSPDYTEQYINE--INKLNALLKQK 1021 N + E N+ +E+ ++ + L+L + + ++ + S +Q I+ N + L+ +K Sbjct: 1241 TNQLSEKDNLLIEKSQIISDLELQLRESYKERSSSSSLHQQQQMISPDLSNSNDELIVEK 1300 Query: 1022 DEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEE-----------MQRVSKQ 1070 +E I L +K + + + + K + +EEE QR+ Q Sbjct: 1301 EEIINELKEKNQQLEQQLQDLCQQFNKNKQENELKCQQLEEENDGWKNEIDTLNQRLKTQ 1360 Query: 1071 LLDSKQHNEELQ---ILVREQDDQIKELKE 1097 L++ + ELQ ++ Q+ IK+L++ Sbjct: 1361 SLNTSPDSSELQQQLDIISNQELNIKQLEK 1390 Score = 105 bits (253), Expect = 8e-21 Identities = 172/869 (19%), Positives = 379/869 (43%), Gaps = 65/869 (7%) Query: 144 VTHLSNTIKEKDNALSVL----QVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXX 199 + L + + EK + ++ L + +++ ++ L +++ EKD+ + Sbjct: 579 IDQLQDNLNEKQDKINELVENNESSSDELQSKLIQLSDQLQEKDEKLLNNQSIINELQSN 638 Query: 200 XXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQ--RLLKD--IESKDVRISSLEE 255 E+ + ++ I + E KD+ + R L+ IE++D ++ L + Sbjct: 639 LNENQNKINELIENNQSSSDELNSKLIKLSDELKDKNENVRSLETSIIENQD-KLDQLIQ 697 Query: 256 ANKL----LEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIE 311 +N++ L++ E + ++L + + Q IE + E++ Sbjct: 698 SNQVTVNELQSKLNEKEININQLIENNQSSLDELQSKLNEKQNEINQLIENNQSSSDELQ 757 Query: 312 EKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLIS 371 K + + ++EL K+ L N ++ EL++KL + E K K +I Sbjct: 758 SKLNEKHQEISELQSKLNELIENN---ESSSDELQSKLIQLSDELKEKDEKLKSLDSIII 814 Query: 372 RKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEK 431 + KS +Q S + L ++K +NEI +L QS + +L K ++EK Sbjct: 815 ENQEK-LVQLTKS--NQDSLDELQSKLNEK--QNEINELIENNQSSSNELQSK---LNEK 866 Query: 432 DTXXXXXXXXX-XGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELN 490 D L ++L +HQ+ E S ++ N +NE+ + E EL Sbjct: 867 QNEINLLIENNQSSSDELQSKLNEKHQEINELQSKLNEKQNK--INELVENNESSSDELQ 924 Query: 491 DEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKV 550 ++ ++ ++L+ E Q+ I ++ + +++S KL + Q ID ++ Sbjct: 925 SKLIQLS-----DQLQEKENQLKSFESSIIERDEKLNQLQS----KLNEKQNEIDQITEN 975 Query: 551 SDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIE--SDVYKKMIEMENL 608 + S+ L E +L++K E+ + N Q L + S ++ E +++ +K ++ L Sbjct: 976 NQSS-----LDELQSNLNEKQNEINQLIENNQSSLDELQS-KLNEKLNEINEKDNKINEL 1029 Query: 609 AETRLKAISLLESQKFD-LVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEE- 666 +T +++S + KF+ L QEL K ++ ++ D++ S++ +E+ + L+ Sbjct: 1030 IQTN-ESLSKDQQSKFENLEQELEEKNNKILDLNSQIIDVNHQFSEKE-NELNQLQLKLI 1087 Query: 667 QIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEK 726 + D ++ + I N +KE+ D +N+ E+ + ++ ++ DL ++L Sbjct: 1088 EKDQEIENQNNKIIDINNQLNEKEKEININNDNDNNNEENIQLIEELKEKLQDLENELN- 1146 Query: 727 MSAEKISELLAKINH-EEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESI 785 + + ++E IN +E+ K+ ++ + K QE + I + + L++ + ++ Sbjct: 1147 LEKDTVNEKNDDINELKEEIKLISE-KLSEKEQELNEMINDYDESLNEINDQKDLVKSLN 1205 Query: 786 AVMEDRRYSLERKADQLGSYLQEK-QKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEI 844 + + + K +++ S +E + S+ + ++L + +L++ +++ L++ Sbjct: 1206 ERLTNAHLKINEKDNEIHSLSKEGFNEIQSQLNLITNQLSEKDNLLIEKSQIISDLELQL 1265 Query: 845 EHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLE 904 KE + + L ++ Q + LS+ +VEK + + ++ + + QL+DL Sbjct: 1266 RESYKE-RSSSSSLHQQQQMISPDLSNSNDEL--IVEKEEIINELKEKNQQLEQQLQDLC 1322 Query: 905 SNLKRITHEHQTLIVQK-------KKEIEDLEIEFNTQIESAIRDKKVLNEKYE--KNIE 955 + E++ Q K EI+ L TQ + D L ++ + N E Sbjct: 1323 QQFNKNKQENELKCQQLEEENDGWKNEIDTLNQRLKTQSLNTSPDSSELQQQLDIISNQE 1382 Query: 956 Y-VTQLEAQLQEYKNNIENLNMNVEELNK 983 + QLE +LQ+ I+NL VEE+NK Sbjct: 1383 LNIKQLEKELQDKSGKIDNLEYQVEEMNK 1411 >UniRef50_A2DDP2 Cluster: Viral A-type inclusion protein, putative; n=1; Trichomonas vaginalis G3|Rep: Viral A-type inclusion protein, putative - Trichomonas vaginalis G3 Length = 2120 Score = 194 bits (473), Expect = 2e-47 Identities = 300/1496 (20%), Positives = 632/1496 (42%), Gaps = 111/1496 (7%) Query: 147 LSNTIKEKDNALSVLQVKMKIMETTILDLQEKI----NEKDQIIEAKNKATTXXXXXXXX 202 L + +KE + S L+ MK+++ DL+E+I N DQI+E K K Sbjct: 506 LRSQLKENKDYQSQLE-NMKLIQEENDDLKERIGDMSNLSDQILELKKKLNDSENEKEIL 564 Query: 203 XXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEA 262 +D ++ + F + ++ K E Q L K I + +IS E K Sbjct: 565 RKQIDNLCKDDEEEDVP----TFSKVISDLKVENQILKKKISDSE-QISKENEDLKKQIN 619 Query: 263 ARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLE--IAN 320 +I E+ +L E+ + KQ+ + + +LE + N Sbjct: 620 EYIDIENENDELKDEISTLQNNIQKITERNEEIEKQNDDLKKNNDDLHVKIHNLEQKVDN 679 Query: 321 MTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTAS 380 +T L ++ + + I++ N L+NK A+ S + K L R T Sbjct: 680 LTNLNNELTINQMKYEDIKEENDLLKNKSAS--PVSATPRTQQNKIQQLQMRNDELKTEI 737 Query: 381 KMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDK--EYVISEKDTXXXXX 438 ++ + +D D K NEI L+ + LN L D + ++ +++ Sbjct: 738 EILHQTIDKLTSARIKDNDSKTVDNEIDLLKKENERLNAMLDDSSMQIIMLQQEIDENKS 797 Query: 439 XXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELN--DEIKDV 496 + L Q++ E Q+H P + N+ E K+QE++++ N D++++ Sbjct: 798 NSLKQENEKLQEQIE-ELQKHSPSPKKLQQENNSLK-QENEKLQEEIEELQNTVDKLQNE 855 Query: 497 N-VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNK 555 N ++ L E+ +++I +L ++ + ++K+N + +K + + + N+ Sbjct: 856 NNLQSLQEENDKLQDEIEELQSTVEKLQQENEELKNNKPIYSPSPKKLQNENNSLKQENE 915 Query: 556 EIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKA 615 ++ EEL + K+ + LQ ++ E + K+ IE N +++ + Sbjct: 916 KLQEQIEELQNTIDKLQNSNKSPNKLQQE----NNSLKQEIENLKEEIEQNN--KSKSYS 969 Query: 616 ISLLESQKFDLVQELHILQQKYDEVEDKLADISQ----LQSDQ-VCSEIKSVHLEEQI-- 668 + L+++ L QE LQ++ +E+++ + + Q L++++ V K + E + Sbjct: 970 PNKLQNENESLKQENEKLQEQIEELQNTVEKLQQENDLLKNNKSVSPSPKKLQQENDLLK 1029 Query: 669 --DALSASKKELALVIENLKLDKEQLYGTIKDLEN--DKEDIMNKLQNYIQ-ENMDLTDK 723 ++S S K+L +LK + E+L I++L+N DK NK +Q EN + + Sbjct: 1030 NNKSVSPSPKKLQNENNSLKQENEKLQEEIEELQNTIDKLQNSNKSPKKLQQENKSMLNS 1089 Query: 724 LEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEE 783 K+ E E L + N + Q +I+ K+Q+ + ++N +S+ + RL++ Sbjct: 1090 PNKLQNEY--ETLQEENEKLQDEIEELQSTVEKLQQENDLLKNSKSKSVSPSPK--RLQQ 1145 Query: 784 SIAVMEDRRYSLERKADQLGSYLQEKQKAYSE-YTIQEDELVNRLAVLMDHDRVVEKQLL 842 ++ L+ + +QL + +++ Q S+ Y+ +L N L + +++Q+ Sbjct: 1146 ENNSLKQENEKLQEEINQLQNTIEKLQNNKSKLYSPSPKKLQNENESLKQENEKLQEQIE 1205 Query: 843 EIEHEN----------KELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESE 892 +++ EN ++LQ++N L +EN+ LQ + +Q L ++ N++ + Sbjct: 1206 KLQQENDSKPKYSPSPRKLQQENNSLKQENEKLQEEIDQLQNTIEKLQQENNKSKSLLNT 1265 Query: 893 STKYQTQLRDLESNLKRITHEHQTL-IVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYE 951 K Q + L+ ++ E + L +K + E+ E++ N I S KK+ NE Sbjct: 1266 PNKLQNEYETLQEENDKLQDEIEELQSTVEKLQQENEELKNNKPIYSP-SPKKLQNENNS 1324 Query: 952 KNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLE--LIDKHVQ--KQQTQSPDYTEQY 1007 E +L+ +++E +N I+ L + + NK+ E + + ++ K++ + + ++ Y Sbjct: 1325 LKQEN-EKLQEEIEELQNTIDKLQNSNKSPNKLQQENNSLKQEIENLKEEIEQNNKSKSY 1383 Query: 1008 I-NEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQR 1066 N++ N LKQ++E+ L ++I Q + + E+ L + + +++Q Sbjct: 1384 SPNKLQNENESLKQENEK---LQEEIEELQNTVEKL--QQENDLLKNNKSVSPSPKKLQN 1438 Query: 1067 VSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDAN 1126 + L KQ NE+LQ + E + I +L+ + + PK + + M + N Sbjct: 1439 ENNSL---KQENEKLQEEIEELQNTIDKLQNSNKS-----PKK----LQQENKSMLNSPN 1486 Query: 1127 NVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELT 1186 + L+ + EE + QE N++ + +L+ N L Sbjct: 1487 KLQNEYETLQEENEKLQDEIEELQSTVEKLQQENDLLKNSKSKSVSPSPKRLQQENNSLK 1546 Query: 1187 GHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQR 1246 + QE+INQL++ +E+L L S + + + ++ Q ++ E ++ + Sbjct: 1547 QENEKLQEEINQLQNTIEKLQNNKSKLYSPSPKKLQNENESLKQENEKLQEQIEKLQQEN 1606 Query: 1247 EAD---------FQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQN 1297 ++ Q+ + L+ + + + +QL ++++ QE + LQN Sbjct: 1607 DSKPKYSPSPRKLQQENNSLKQENEKLQEEIDQLQNTIEKLQQENNKSKSLLNTPNKLQN 1666 Query: 1298 KLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQ 1357 + + +E LQ+K ++ + IE L+ E E+ K L+ EN+ Sbjct: 1667 EYETLQEENDKLQDKIEELQSTIEKLQQENEELK-NNKPIYSPSPKKLQNENNSLKQENE 1725 Query: 1358 SYK-------------QMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLE 1404 + Q++ +S + +EN LK+ + + K+ + Sbjct: 1726 KLQEEIEELQNTIDKLQIENKSPNKLQQENNSLKQEIENLKEEIEQNNKSKSYSPKKLQQ 1785 Query: 1405 LTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRL 1464 + L+ ++ ++ ++ E T+ + + EN Q L E +++D E +S + L+ Sbjct: 1786 ENNSLKQENEKLQEEIDELQNTVDKLQN--ENNLQSLQEENDKLQDEIEELQSTVEKLQQ 1843 Query: 1465 KMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEE---EVAKTNE 1521 + E N+ + KL E N E+ L +++ EL +++ E N+ Sbjct: 1844 ENEELKNNKPIYSPSPK----KLQNENNSLKQENEKLQEEIEELQNTIDKLQIENKSPNK 1899 Query: 1522 MQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMN 1577 +Q + + EI L +EI S K+Q+ + + E++D N Sbjct: 1900 LQQENNSLKQEIENLKEEIEQNNKSKSYSPKKLQQENNSLKQENEKLQEEIDELQN 1955 Score = 176 bits (429), Expect = 4e-42 Identities = 307/1387 (22%), Positives = 599/1387 (43%), Gaps = 148/1387 (10%) Query: 240 LKDIESKDV--RISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAK 297 +KD +SK V I L++ N+ L A + S++ L QE+++ Sbjct: 752 IKDNDSKTVDNEIDLLKKENERLNAMLDDSSMQIIMLQQEIDENKSNSLKQENEKLQEQI 811 Query: 298 QSIEPSCEEKTEIE-EKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTES 356 + ++ +++ E SL+ N +L ++IE L++ +++ EN L ++ E+ Sbjct: 812 EELQKHSPSPKKLQQENNSLKQEN-EKLQEEIEELQNTVDKLQN-----ENNLQSLQEEN 865 Query: 357 KAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQS 416 + ++ + + N K P S + L + + +NE KL+ I+ Sbjct: 866 DKLQDEIEELQSTVEKLQQENEELKNNKPIYSPSPKKLQNENNSLKQENE--KLQEQIEE 923 Query: 417 LNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVN 476 L ++ +DK + + I L+ E +Q+ + S N Sbjct: 924 L-QNTIDK---LQNSNKSPNKLQQENNSLKQEIENLKEEIEQNNKSKSY--------SPN 971 Query: 477 EIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLK 536 ++ E LKQE N+++++ IE+L++ E++ Q ND + KN V + K K Sbjct: 972 KLQNENESLKQE-NEKLQEQ-----IEELQNTVEKLQQENDLL----KNNKSVSPSPK-K 1020 Query: 537 LKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIES 596 L+Q + N VS S K +L E + L Q+ +L+EE LQ + +D ++ S Sbjct: 1021 LQQENDLLKNNKSVSPSPK---KLQNENNSLKQENEKLQEEIEELQ-NTID----KLQNS 1072 Query: 597 DVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQ-V 655 + K ++ EN ++ L + + L+++ L +E LQ DE+E+ + + +LQ + + Sbjct: 1073 NKSPKKLQQEN--KSMLNSPNKLQNEYETLQEENEKLQ---DEIEELQSTVEKLQQENDL 1127 Query: 656 CSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQ 715 KS + L L E L+ + QL TI+ L+N+K + + +Q Sbjct: 1128 LKNSKSKSVSPSPKRLQQENNSLKQENEKLQEEINQLQNTIEKLQNNKSKLYSPSPKKLQ 1187 Query: 716 -ENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKY 774 EN L K EK+ E + K+ E SK + K+Q+ + +++ E K Sbjct: 1188 NENESL-----KQENEKLQEQIEKLQQENDSKPKYSPS-PRKLQQEN---NSLKQENEKL 1238 Query: 775 KSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEY-TIQEDELVNRLAVLMDH 833 + I +L+ +I L+++ ++ S L K +EY T+QE+ L D Sbjct: 1239 QEEIDQLQNTIE-------KLQQENNKSKSLLNTPNKLQNEYETLQEEN-----DKLQDE 1286 Query: 834 DRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESES 893 ++ + +++ EN+EL+ I + LQ + ++Q L E ++ E ++ Sbjct: 1287 IEELQSTVEKLQQENEELKNNKPIYSPSPKKLQNENNSLKQENEKLQE-----EIEELQN 1341 Query: 894 TKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKN 953 T + Q + N ++ E+ +L K+EIE+L+ E IE + K K + Sbjct: 1342 TIDKLQNSNKSPN--KLQQENNSL----KQEIENLKEE----IEQNNKSKSYSPNKLQNE 1391 Query: 954 IEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINK 1013 E + Q +LQE IE L VE+L + N +L+ + K + SP + N + + Sbjct: 1392 NESLKQENEKLQE---EIEELQNTVEKLQQEN-DLLKNN--KSVSPSPKKLQNENNSLKQ 1445 Query: 1014 LNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLD 1073 N L+++ EE+ K+ N+ S + + +S L KL+N E +Q +++L D Sbjct: 1446 ENEKLQEEIEELQNTIDKLQNSNKSPKKLQQENKSMLNS-PNKLQNEYETLQEENEKLQD 1504 Query: 1074 SKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXX 1133 + + +++++D +K K ++ + E + E + ++ N + Sbjct: 1505 EIEELQSTVEKLQQENDLLKNSKSKSVSPSPKRLQQENNSLKQENEKLQEEINQLQNTIE 1564 Query: 1134 XXXXXXXXL------KVQEEEEFI-QERSVLQEQSAKLNTE--LQECYTKIIQ-LETLNT 1183 L K+Q E E + QE LQEQ KL E + Y+ + L+ N Sbjct: 1565 KLQNNKSKLYSPSPKKLQNENESLKQENEKLQEQIEKLQQENDSKPKYSPSPRKLQQENN 1624 Query: 1184 ELTGHDVVNQEQINQLKSKLEQLNTEND---NLLSTVAELRSSISSAVDQRGFEIAELWK 1240 L + QE+I+QL++ +E+L EN+ +LL+T +L++ + ++ ++ Sbjct: 1625 SLKQENEKLQEEIDQLQNTIEKLQQENNKSKSLLNTPNKLQNEYETLQEENDKLQDKI-- 1682 Query: 1241 QHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQ 1300 + L Q+ EL+ + ++L + S QE +E++ + +KLQ Sbjct: 1683 EELQSTIEKLQQENEELKNNKPIYSPSPKKLQNENNSLKQENEKLQEEIEELQNTIDKLQ 1742 Query: 1301 DKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYK 1360 + + LQ++ + +IE L+ EIE + L+ EN S K Sbjct: 1743 IENKSPNKLQQENNSLKQEIENLKEEIEQNNKS-----------KSYSPKKLQQENNSLK 1791 Query: 1361 QMQEQSILNINE-ENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQK 1419 Q E+ I+E +N K + ++ D ++ +L+ ++ E+ Sbjct: 1792 QENEKLQEEIDELQNTVDKLQNENNLQSLQEENDKLQDEIEELQSTVEKLQQENEELKNN 1851 Query: 1420 THEYTITLTQRNDEFENVRQQLVEYEKRIEDL--TYEKES--ELAILRLKMHENANHYET 1475 Y+ + + +E +++Q+ + ++ IE+L T +K + +L+ N+ E Sbjct: 1852 KPIYSPSPKKLQNENNSLKQENEKLQEEIEELQNTIDKLQIENKSPNKLQQENNSLKQEI 1911 Query: 1476 MQKESEIER---------VKLIEELNVKITESVSLNKQVAELN------------KALEE 1514 + EIE+ KL +E N E+ L +++ EL ++L+E Sbjct: 1912 ENLKEEIEQNNKSKSYSPKKLQQENNSLKQENEKLQEEIDELQNTVDKLQNENNLQSLQE 1971 Query: 1515 EVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKH---VSFASDTKQGRDEQ 1571 E K + L++ ++ N+E+ N + + S K+Q + ++ Q E+ Sbjct: 1972 ENDKLQDEIEELQSTVEKLQQENEELKNNKPIYSPSPKKLQNENNSLKQENEKLQEEIEE 2031 Query: 1572 LDNTMNK 1578 L NT++K Sbjct: 2032 LQNTIDK 2038 Score = 174 bits (424), Expect = 1e-41 Identities = 302/1446 (20%), Positives = 630/1446 (43%), Gaps = 139/1446 (9%) Query: 212 EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSL-EEANKLLEAARFEISLE 270 +D + ++QE + + D + K E ++ I+ L + N+ L+ EI Sbjct: 164 DDLSRLNVQLQEKIKLLSTSYTDLSAKFDKQNEDHEIEIAKLIDRQNERLK----EIEES 219 Query: 271 HSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIEL 330 H Q+++ K+ ++ S +E ++EE L+ E TK I L Sbjct: 220 HKSNIQQIQTNKDGLTNQIQQEFTKTKEDLDKSRKEYKQLEE---LQRKAQEENTKTISL 276 Query: 331 LEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLS 390 L N QI Q +LE + + AV KK + R + K Q Sbjct: 277 L---NIQINQLQNQLEKAYSGKQADDVAV----KKNIADLERSNAE------KDVVIQSL 323 Query: 391 SETLNQDTDKKIN-KNEIAKLEMVIQSLNKDLVDKEYVI---SEK-DTXXXXXXXXXXGK 445 S + + +K N + +I++ E I+ LN D + I S K D Sbjct: 324 STKVGRFEEKVSNLEAKISEYEKTIKQLNNSKEDLQKQINNFSNKIDIERAEKQIYIENN 383 Query: 446 DTLIAQLQ----------LEHQQHMEGPSL--IHVGTNTEDVNEIAKVQEQ---LKQELN 490 + L Q+Q E QQ +E + + + NTE N I +QE+ L+Q+L+ Sbjct: 384 NDLKEQIQNDEIKFQKERKEFQQELENLRIKFVQLSNNTEKDNLIQHLQEEINALRQKLS 443 Query: 491 DEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKV 550 + K V +S E IT L +I NM+K+++ ++++K I+N+ + Sbjct: 444 EYSKIVENSKSTPGKESYESTITNLRTQI-----NMLKLEN------QEIKKDIENYDTM 492 Query: 551 SDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAE 610 N+E+ + ++L ++ + + + N++L + D D+ +++ +M NL++ Sbjct: 493 EKQNEEMKKQMDDLRSQLKENKDYQSQLENMKLIQEEND-------DLKERIGDMSNLSD 545 Query: 611 TRLKAISLLESQKFDLVQELHILQQKYDEV--EDKLADISQLQSDQVCSEIKSVHLEEQI 668 L+ L+ + D E IL+++ D + +D+ D+ +V S++K +E QI Sbjct: 546 QILE----LKKKLNDSENEKEILRKQIDNLCKDDEEEDVPTF--SKVISDLK---VENQI 596 Query: 669 DALSASKKELALVIENLKLDKE-QLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKM 727 S E + EN L K+ Y I++ ++ +D ++ LQN IQ+ + +++EK Sbjct: 597 LKKKISDSE-QISKENEDLKKQINEYIDIENENDELKDEISTLQNNIQKITERNEEIEKQ 655 Query: 728 S---AEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENI--ESELSKYKSRICRLE 782 + + +L KI++ EQ K+ ++ ++ + E+I E++L K KS + Sbjct: 656 NDDLKKNNDDLHVKIHNLEQ-KVDNLTNLNNELTINQMKYEDIKEENDLLKNKS-ASPVS 713 Query: 783 ESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYT---IQEDE---LVNRLAVL-MDHDR 835 + +++ L+ + D+L + ++ + + T I++++ + N + +L +++R Sbjct: 714 ATPRTQQNKIQQLQMRNDELKTEIEILHQTIDKLTSARIKDNDSKTVDNEIDLLKKENER 773 Query: 836 ---VVEKQLLEIEHENKEL-QKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAES 891 +++ ++I +E+ + K+ L +EN+ LQ + ++Q+H + + + + Sbjct: 774 LNAMLDDSSMQIIMLQQEIDENKSNSLKQENEKLQEQIEELQKHSPSPKKLQQENNSLKQ 833 Query: 892 ESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYE 951 E+ K Q ++ +L++ + ++ +E+ +Q++ + EIE +++S + + NE+ + Sbjct: 834 ENEKLQEEIEELQNTVDKLQNENNLQSLQEENDKLQDEIE---ELQSTVEKLQQENEELK 890 Query: 952 KNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEI 1011 N + +LQ N+++ N ++E + IDK + +SP+ +Q N + Sbjct: 891 NNKPIYSPSPKKLQNENNSLKQENEKLQEQIEELQNTIDK--LQNSNKSPNKLQQENNSL 948 Query: 1012 NKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQL 1071 + LK++ E+ N + + KL + +L+N E++Q+ + L Sbjct: 949 KQEIENLKEEIEQNNKSKSYSPNKLQNENESLKQENEKLQEQIEELQNTVEKLQQENDLL 1008 Query: 1072 LDSKQHNEELQILVREQDDQIKELKET-----KLTFEMNIPKTEGMIISSTIEPMSDDAN 1126 ++K + + L ++++D +K K KL E N K E + IE + + + Sbjct: 1009 KNNKSVSPSPKKL-QQENDLLKNNKSVSPSPKKLQNENNSLKQENEKLQEEIEELQNTID 1067 Query: 1127 NVDXXXXXXXXXXXXLK--VQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTE 1184 + K + + E LQE++ KL E++E + + +L+ N Sbjct: 1068 KLQNSNKSPKKLQQENKSMLNSPNKLQNEYETLQEENEKLQDEIEELQSTVEKLQQENDL 1127 Query: 1185 LTGHDVVN--------QEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIA 1236 L + Q++ N LK + E+L E + L +T+ +L+++ S ++ Sbjct: 1128 LKNSKSKSVSPSPKRLQQENNSLKQENEKLQEEINQLQNTIEKLQNNKSKLYSPSPKKL- 1186 Query: 1237 ELWKQHLAQREADFQKTEHELRVQLSAFESKYE---QLLDSVQSSTQEETNKIVTMEQVT 1293 + + L Q Q+ +L+ Q + + KY + L +S ++E K+ E++ Sbjct: 1187 QNENESLKQENEKLQEQIEKLQ-QENDSKPKYSPSPRKLQQENNSLKQENEKL--QEEID 1243 Query: 1294 SLQN---KLQDKEEHLRNLQEKYADVINQIEILRSE---IEDEKVAFXXXXXXXXXXXXX 1347 LQN KLQ + ++L + N+ E L+ E ++DE Sbjct: 1244 QLQNTIEKLQQENNKSKSLLNTPNKLQNEYETLQEENDKLQDEIEELQSTVEKLQQENEE 1303 Query: 1348 XXXDLRTENQSYKQMQEQSILNINEENAQLK---KSSXXXXXXXXXXXXRVNDAEAKVLE 1404 + + S K++Q ++ ++ +EN +L+ + N + + Sbjct: 1304 LKNNKPIYSPSPKKLQNEN-NSLKQENEKLQEEIEELQNTIDKLQNSNKSPNKLQQENNS 1362 Query: 1405 LTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDL--TYEK---ESEL 1459 L ++E EI Q + + + +E E+++Q+ + ++ IE+L T EK E++L Sbjct: 1363 LKQEIENLKEEIEQNNKSKSYSPNKLQNENESLKQENEKLQEEIEELQNTVEKLQQENDL 1422 Query: 1460 AILRLKMHENANHYETMQKESEIERVKL---IEELNVKITESVSLNKQVAELNKALEEEV 1516 + + + + E KL IEEL I + + NK +L + + + Sbjct: 1423 LKNNKSVSPSPKKLQNENNSLKQENEKLQEEIEELQNTIDKLQNSNKSPKKLQQENKSML 1482 Query: 1517 AKTNEMQTALENQEIEIVTLNDEITNLQNMV---RASSSKIQKHVSFASDTKQGRDEQLD 1573 N++Q E + E L DEI LQ+ V + + ++ S + R +Q + Sbjct: 1483 NSPNKLQNEYETLQEENEKLQDEIEELQSTVEKLQQENDLLKNSKSKSVSPSPKRLQQEN 1542 Query: 1574 NTMNKE 1579 N++ +E Sbjct: 1543 NSLKQE 1548 Score = 163 bits (397), Expect = 3e-38 Identities = 264/1217 (21%), Positives = 529/1217 (43%), Gaps = 100/1217 (8%) Query: 147 LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXX 206 L I+E N + LQ K LQ++ N Q IE + Sbjct: 917 LQEQIEELQNTIDKLQNSNKSPNK----LQQENNSLKQEIENLKEEIEQNNKSKSYSPNK 972 Query: 207 XXXXXEDTKQQMTKMQENFIAME--AEWKDEKQRLLKDIESKDVRISSLEEANKLLEAAR 264 E KQ+ K+QE ++ E ++ LLK+ +S L++ N LL+ + Sbjct: 973 LQNENESLKQENEKLQEQIEELQNTVEKLQQENDLLKNNKSVSPSPKKLQQENDLLKNNK 1032 Query: 265 F------EISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEI 318 ++ E++ L QE E+ L + P +K + E K L Sbjct: 1033 SVSPSPKKLQNENNSLKQENEKLQEEIEELQNTIDKLQNSNKSP---KKLQQENKSMLNS 1089 Query: 319 ANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAV-SSPSKKGSPLISRKSGRN 377 N +L + E L+ N +++ +EL++ + + E+ + +S SK SP R N Sbjct: 1090 PN--KLQNEYETLQEENEKLQDEIEELQSTVEKLQQENDLLKNSKSKSVSPSPKRLQQEN 1147 Query: 378 TASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXX 437 + K ++ Q L Q+T +K+ N K ++ S K + E + E + Sbjct: 1148 NSLKQENEKLQEEINQL-QNTIEKLQNN---KSKLYSPSPKKLQNENESLKQENEKLQEQ 1203 Query: 438 XXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNT-EDVNEIAKVQEQLKQELNDEIKDV 496 D+ + E SL E+++++ E+L+QE N + Sbjct: 1204 IEKLQQENDSKPKYSPSPRKLQQENNSLKQENEKLQEEIDQLQNTIEKLQQENNKSKSLL 1263 Query: 497 NVKDLIE-KLKSAEEQITQLNDEIDAANKNMIKVKS-NHKLKLKQMQKTIDNFSKVSDSN 554 N + ++ + ++ +E+ +L DEI+ + K++ N +LK + + +++N Sbjct: 1264 NTPNKLQNEYETLQEENDKLQDEIEELQSTVEKLQQENEELKNNKPIYSPSPKKLQNENN 1323 Query: 555 ---KEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAET 611 +E +L EE+ L + +L+ + L ++ E + K+ IE N ++ Sbjct: 1324 SLKQENEKLQEEIEELQNTIDKLQNSNKSPN-KLQQENNSLKQEIENLKEEIEQNN--KS 1380 Query: 612 RLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDAL 671 + + + L+++ L QE LQ++ +E+++ + + Q + + KSV Sbjct: 1381 KSYSPNKLQNENESLKQENEKLQEEIEELQNTVEKLQQ--ENDLLKNNKSV--------- 1429 Query: 672 SASKKELALVIENLKLDKEQLYGTIKDLEN--DKEDIMNKLQNYIQ-ENMDLTDKLEKMS 728 S S K+L +LK + E+L I++L+N DK NK +Q EN + + K+ Sbjct: 1430 SPSPKKLQNENNSLKQENEKLQEEIEELQNTIDKLQNSNKSPKKLQQENKSMLNSPNKLQ 1489 Query: 729 AEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVM 788 E E L + N + Q +I+ K+Q+ + ++N +S+ + RL++ + Sbjct: 1490 NEY--ETLQEENEKLQDEIEELQSTVEKLQQENDLLKNSKSKSVSPSPK--RLQQENNSL 1545 Query: 789 EDRRYSLERKADQLGSYLQEKQKAYSE-YTIQEDELVNRLAVLMDHDRVVEKQLLEIEHE 847 + L+ + +QL + +++ Q S+ Y+ +L N L + +++Q+ +++ E Sbjct: 1546 KQENEKLQEEINQLQNTIEKLQNNKSKLYSPSPKKLQNENESLKQENEKLQEQIEKLQQE 1605 Query: 848 N----------KELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQ 897 N ++LQ++N L +EN+ LQ + +Q L ++ N++ + K Q Sbjct: 1606 NDSKPKYSPSPRKLQQENNSLKQENEKLQEEIDQLQNTIEKLQQENNKSKSLLNTPNKLQ 1665 Query: 898 TQLRDLESNLKRITHEHQTL-IVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEY 956 + L+ ++ + + L +K + E+ E++ N I S KK+ NE E Sbjct: 1666 NEYETLQEENDKLQDKIEELQSTIEKLQQENEELKNNKPIYSP-SPKKLQNENNSLKQEN 1724 Query: 957 VTQLEAQLQEYKNNIENLNMNVEELNKMNLE--LIDKHVQ--KQQTQSPDYTEQYI-NEI 1011 +L+ +++E +N I+ L + + NK+ E + + ++ K++ + + ++ Y ++ Sbjct: 1725 -EKLQEEIEELQNTIDKLQIENKSPNKLQQENNSLKQEIENLKEEIEQNNKSKSYSPKKL 1783 Query: 1012 NKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQL 1071 + N LKQ++E++ ++ N V + ++ +S L + KL++ EE+Q ++L Sbjct: 1784 QQENNSLKQENEKLQEEIDELQNT-VDKLQNENNLQS-LQEENDKLQDEIEELQSTVEKL 1841 Query: 1072 LDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXX 1131 +Q NEEL+ + I KL E N K E + IE + N +D Sbjct: 1842 ---QQENEELK-----NNKPIYSPSPKKLQNENNSLKQENEKLQEEIEELQ---NTIDKL 1890 Query: 1132 XXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVV 1191 K+Q+E +++ ++ + N + + K +Q E N L + Sbjct: 1891 QIENKSPN---KLQQENNSLKQEIENLKEEIEQNNKSKSYSPKKLQQE--NNSLKQENEK 1945 Query: 1192 NQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQ 1251 QE+I++L++ +++L EN NL S+ D+ EI EL Q ++ Q Sbjct: 1946 LQEEIDELQNTVDKLQNEN-NL--------QSLQEENDKLQDEIEEL--QSTVEK---LQ 1991 Query: 1252 KTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQE 1311 + EL+ + ++L + S QE +E++ + +KLQ + + LQ+ Sbjct: 1992 QENEELKNNKPIYSPSPKKLQNENNSLKQENEKLQEEIEELQNTIDKLQIENKSPNKLQQ 2051 Query: 1312 KYADVINQIEILRSEIE 1328 + + +IE L+ EIE Sbjct: 2052 ENNSLKQEIENLKEEIE 2068 Score = 155 bits (375), Expect = 1e-35 Identities = 241/1193 (20%), Positives = 505/1193 (42%), Gaps = 75/1193 (6%) Query: 233 KDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXX 292 K E ++L + IE I L+ +NK + ++ E++ L QE+E Sbjct: 911 KQENEKLQEQIEELQNTIDKLQNSNK----SPNKLQQENNSLKQEIENLKEEIEQNNKSK 966 Query: 293 XXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATM 352 + ++ E + EK +I EL +E L+ N + + NK + + Sbjct: 967 SY-SPNKLQNENESLKQENEKLQEQIE---ELQNTVEKLQQEN-DLLKNNKSVSPSPKKL 1021 Query: 353 GTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEM 412 E+ + + +K SP + N + K ++ Q E L DK N N+ K Sbjct: 1022 QQENDLLKN-NKSVSPSPKKLQNENNSLKQENEKLQEEIEELQNTIDKLQNSNKSPKK-- 1078 Query: 413 VIQSLNKDLVDKEYVI-SEKDTXXXXXXXXXXGKDTLIAQLQLEHQQH--MEGPSLIHVG 469 +Q NK +++ + +E +T + L + ++ Q++ ++ V Sbjct: 1079 -LQQENKSMLNSPNKLQNEYETLQEENEKLQDEIEELQSTVEKLQQENDLLKNSKSKSVS 1137 Query: 470 TNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKV 529 + + + + +Q ++L +EI + ++ IEKL++ + ++ + + N+N Sbjct: 1138 PSPKRLQQENNSLKQENEKLQEEINQL--QNTIEKLQNNKSKLYSPSPK-KLQNENESLK 1194 Query: 530 KSNHKLK--LKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVD 587 + N KL+ ++++Q+ D+ K S S + +L +E + L Q+ +L+EE LQ + Sbjct: 1195 QENEKLQEQIEKLQQENDSKPKYSPSPR---KLQQENNSLKQENEKLQEEIDQLQNTIEK 1251 Query: 588 YDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADI 647 + +++N ET + L+ + +L + LQQ+ +E+++ Sbjct: 1252 LQQENNKSKSLLNTPNKLQNEYETLQEENDKLQDEIEELQSTVEKLQQENEELKNNKPIY 1311 Query: 648 S----QLQSDQVCSEIKSVHLEEQIDAL--------SASKKELALVIEN--LKLDKEQLY 693 S +LQ++ + ++ L+E+I+ L +++K L EN LK + E L Sbjct: 1312 SPSPKKLQNENNSLKQENEKLQEEIEELQNTIDKLQNSNKSPNKLQQENNSLKQEIENLK 1371 Query: 694 GTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGI 753 I+ K NKLQN EN L + EK+ E+I EL + +Q + Sbjct: 1372 EEIEQNNKSKSYSPNKLQN---ENESLKQENEKLQ-EEIEELQNTVEKLQQENDLLKNNK 1427 Query: 754 DAKIQERDLYIEN--IESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQK 811 + L EN ++ E K + I L+ +I +++ S ++ + S L K Sbjct: 1428 SVSPSPKKLQNENNSLKQENEKLQEEIEELQNTIDKLQNSNKSPKKLQQENKSMLNSPNK 1487 Query: 812 AYSEY-TIQED---------ELVNRLAVLM-DHDRVVEKQLLEIEHENKELQKKNQILLE 860 +EY T+QE+ EL + + L ++D + + + K LQ++N L + Sbjct: 1488 LQNEYETLQEENEKLQDEIEELQSTVEKLQQENDLLKNSKSKSVSPSPKRLQQENNSLKQ 1547 Query: 861 ENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQ 920 EN+ LQ ++ +Q L + N++ L K Q + L+ +++ + + L Q Sbjct: 1548 ENEKLQEEINQLQNTIEKL--QNNKSKLYSPSPKKLQNENESLKQENEKLQEQIEKL--Q 1603 Query: 921 KKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEE 980 ++ + + +++ K NEK ++ I+ + +LQ+ N ++L +N Sbjct: 1604 QENDSKPKYSPSPRKLQQENNSLKQENEKLQEEIDQLQNTIEKLQQENNKSKSL-LNTPN 1662 Query: 981 LNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYM 1040 + E + + K Q + + + I ++ + N LK +K+ N S Sbjct: 1663 KLQNEYETLQEENDKLQDKIEEL-QSTIEKLQQENEELKNNKPIYSPSPKKLQNENNSLK 1721 Query: 1041 SMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVRE--QDDQIKELKET 1098 + ++ + ++ ++ E + +K ++ +E++ L E Q+++ K Sbjct: 1722 QENEKLQEEIEELQNTIDKLQIENKSPNKLQQENNSLKQEIENLKEEIEQNNKSKSYSPK 1781 Query: 1099 KLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQER-SVL 1157 KL E N K E + I+ + + + + K+Q+E E +Q L Sbjct: 1782 KLQQENNSLKQENEKLQEEIDELQNTVDKLQNENNLQSLQEENDKLQDEIEELQSTVEKL 1841 Query: 1158 QEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTV 1217 Q+++ +L +L+ N L + QE+I +L++ +++L EN + + + Sbjct: 1842 QQENEELKNNKPIYSPSPKKLQNENNSLKQENEKLQEEIEELQNTIDKLQIENKSP-NKL 1900 Query: 1218 AELRSSISSAVDQRGFEI-----AELWKQHLAQREADFQKTEHE-LRVQLSAFESKYEQL 1271 + +S+ ++ EI ++ + Q+E + K E+E L+ ++ ++ ++L Sbjct: 1901 QQENNSLKQEIENLKEEIEQNNKSKSYSPKKLQQENNSLKQENEKLQEEIDELQNTVDKL 1960 Query: 1272 LDSVQ-SSTQEETNKIVT-MEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIED 1329 + S QEE +K+ +E++ S KLQ + E L+N + Y+ +++ + ++ Sbjct: 1961 QNENNLQSLQEENDKLQDEIEELQSTVEKLQQENEELKNNKPIYSPSPKKLQNENNSLKQ 2020 Query: 1330 EKVAFXXXXXXXXXXXXXXXXDLRTEN--QSYKQMQEQSILNINEENAQLKKS 1380 E + ++ N Q +Q I N+ EE Q KS Sbjct: 2021 ENEKLQEEIEELQNTIDKLQIENKSPNKLQQENNSLKQEIENLKEEIEQNNKS 2073 Score = 116 bits (280), Expect = 4e-24 Identities = 181/1000 (18%), Positives = 438/1000 (43%), Gaps = 62/1000 (6%) Query: 149 NTIKEKDNALSVLQVKMKIMETTILDLQ---EKINEKDQIIE-AKNKATTXXXXXXXXXX 204 N+ + N LQ + + ++ I +LQ EK+ +++ +++ +K+K+ + Sbjct: 1088 NSPNKLQNEYETLQEENEKLQDEIEELQSTVEKLQQENDLLKNSKSKSVSPSPKRLQQEN 1147 Query: 205 XXXXXXXEDTKQQMTKMQENFIAMEAE----WKDEKQRLLKDIESKDVRISSLEEANKLL 260 E ++++ ++Q ++ + ++L + ES L+E + L Sbjct: 1148 NSLKQENEKLQEEINQLQNTIEKLQNNKSKLYSPSPKKLQNENESLKQENEKLQEQIEKL 1207 Query: 261 EAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIAN 320 + + ++S ++L+Q Q ++ + E+ + K + Sbjct: 1208 QQEN-DSKPKYSPSPRKLQQENNSLKQENEKLQEEIDQ-LQNTIEKLQQENNKSKSLLNT 1265 Query: 321 MTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTAS 380 +L + E L+ N +++ +EL++ + + E++ + + SP + N + Sbjct: 1266 PNKLQNEYETLQEENDKLQDEIEELQSTVEKLQQENEELKNNKPIYSPSPKKLQNENNSL 1325 Query: 381 KMKSPWSQLSSETLNQDTDKKINKNEIA-KLEMVIQSLNKDLVDKEYVISEKDTXXXXXX 439 K ++ Q E L DK N N+ KL+ SL +++ + + I + + Sbjct: 1326 KQENEKLQEEIEELQNTIDKLQNSNKSPNKLQQENNSLKQEIENLKEEIEQNNKSKSYSP 1385 Query: 440 XXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVN-V 498 ++ + Q + Q+ +E L + + N++ K + + + N + Sbjct: 1386 NKLQNENESLKQENEKLQEEIE--ELQNTVEKLQQENDLLKNNKSVSPSPKKLQNENNSL 1443 Query: 499 KDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIV 558 K EKL+ E++ D++ +NK+ K++ +K L K + + + + N+++ Sbjct: 1444 KQENEKLQEEIEELQNTIDKLQNSNKSPKKLQQENKSMLNSPNKLQNEYETLQEENEKLQ 1503 Query: 559 RLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAE--TRLK-A 615 EEL +K+ + + N + V R+ + + K E E L E +L+ Sbjct: 1504 DEIEELQSTVEKLQQENDLLKNSKSKSVSPSPKRLQQENNSLKQ-ENEKLQEEINQLQNT 1562 Query: 616 ISLLESQKFDLVQ--------ELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQ 667 I L++ K L E L+Q+ +++++++ + Q + L+++ Sbjct: 1563 IEKLQNNKSKLYSPSPKKLQNENESLKQENEKLQEQIEKLQQENDSKPKYSPSPRKLQQE 1622 Query: 668 IDALSASKKELALVIENLKLDKEQLY---GTIKDLENDKEDIMNKLQNYIQENMDLTDKL 724 ++L ++L I+ L+ E+L K L N + N+ + +EN L DK+ Sbjct: 1623 NNSLKQENEKLQEEIDQLQNTIEKLQQENNKSKSLLNTPNKLQNEYETLQEENDKLQDKI 1682 Query: 725 EKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYI----ENIESELSKYKSRICR 780 E++ + E L + N E ++ K+Q + + E ++ E+ + ++ I + Sbjct: 1683 EEL--QSTIEKLQQENEELKNNKPIYSPSPKKLQNENNSLKQENEKLQEEIEELQNTIDK 1740 Query: 781 LE---ESIAVMEDRRYSLERKADQLGSYLQE--KQKAYSEYTIQEDELVNRLAVLMDHDR 835 L+ +S ++ SL+++ + L +++ K K+YS +Q++ L + Sbjct: 1741 LQIENKSPNKLQQENNSLKQEIENLKEEIEQNNKSKSYSPKKLQQEN-----NSLKQENE 1795 Query: 836 VVEKQLLEIEHENKELQKKN--QILLEENQNLQISLSDMQQHYNALVEKANRTDLAESES 893 +++++ E+++ +LQ +N Q L EEN LQ + ++Q L ++ + Sbjct: 1796 KLQEEIDELQNTVDKLQNENNLQSLQEENDKLQDEIEELQSTVEKLQQENEELKNNKPIY 1855 Query: 894 TKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNT-----QIESAIRDK-KVLN 947 + +L++ ++LK+ + Q I + + I+ L+IE + Q ++++ + + L Sbjct: 1856 SPSPKKLQNENNSLKQENEKLQEEIEELQNTIDKLQIENKSPNKLQQENNSLKQEIENLK 1915 Query: 948 EKYEKNIEYVTQLEAQLQEYKNNIENLNMNV-EELNKMNLELIDKHVQKQQTQS-PDYTE 1005 E+ E+N + + +LQ+ N+++ N + EE++++ +DK + QS + + Sbjct: 1916 EEIEQNNKSKSYSPKKLQQENNSLKQENEKLQEEIDELQ-NTVDKLQNENNLQSLQEEND 1974 Query: 1006 QYINEINKLNALLK--QKDEEIIALNQKINNAQVSYM----SMVSDYESKLAQFTTKLEN 1059 + +EI +L + ++ Q++ E + N+ I + + + + KL + +L+N Sbjct: 1975 KLQDEIEELQSTVEKLQQENEELKNNKPIYSPSPKKLQNENNSLKQENEKLQEEIEELQN 2034 Query: 1060 MEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETK 1099 +++Q +K +Q N L+ + ++I++ ++K Sbjct: 2035 TIDKLQIENKSPNKLQQENNSLKQEIENLKEEIEQNNKSK 2074 Score = 103 bits (246), Expect = 5e-20 Identities = 198/1007 (19%), Positives = 410/1007 (40%), Gaps = 106/1007 (10%) Query: 639 EVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKD 698 EV + ++ LQ + ++K L++Q+ + + + IE + Q + +D Sbjct: 33 EVGEYNQNVQDLQEENFSLKMKINALQQQLATVQEQYRTVTTRIEETTY-QYQSNDSSQD 91 Query: 699 LENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQ 758 + + + +KLE+ + E K ++E + + Q +D ++ Sbjct: 92 QNSTDPKTKGGSSSDFGSVAEWMEKLERATKENDDLKREKETYQELA-VTLQNQLDTQVS 150 Query: 759 ERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTI 818 + IE ++ E +L+E I ++ L K D K ++ I Sbjct: 151 NFEFQIEKLQREKDDLSRLNVQLQEKIKLLSTSYTDLSAKFD----------KQNEDHEI 200 Query: 819 QEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNA 878 + +L++R + K ++ NK+ NQI E + + L ++ Y Sbjct: 201 EIAKLIDRQNERLKEIEESHKSNIQQIQTNKD-GLTNQIQQEFTKTKE-DLDKSRKEYKQ 258 Query: 879 LVEKANRTDLAESESTK----YQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNT 934 L E + A+ E+TK Q+ L++ L++ Q V KK I DLE N Sbjct: 259 LEELQRK---AQEENTKTISLLNIQINQLQNQLEKAYSGKQADDVAVKKNIADLE-RSNA 314 Query: 935 QIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEEL--------NKMNL 986 + + I+ L+ K + E V+ LEA++ EY+ I+ LN + E+L NK+++ Sbjct: 315 EKDVVIQS---LSTKVGRFEEKVSNLEAKISEYEKTIKQLNNSKEDLQKQINNFSNKIDI 371 Query: 987 ELIDKHVQ-------KQQTQSPDY-----TEQYINEINKL-------------NALLKQK 1021 E +K + K+Q Q+ + +++ E+ L + L++ Sbjct: 372 ERAEKQIYIENNNDLKEQIQNDEIKFQKERKEFQQELENLRIKFVQLSNNTEKDNLIQHL 431 Query: 1022 DEEIIALNQKINNAQVSYMSMVS-----DYESKLAQFTTKLENMEEEMQRVSKQLLDSKQ 1076 EEI AL QK++ + S YES + T++ ++ E Q + K + + Sbjct: 432 QEEINALRQKLSEYSKIVENSKSTPGKESYESTITNLRTQINMLKLENQEIKKDIENYDT 491 Query: 1077 HNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXX 1136 ++ + + ++ DD +LKE K ++ + E M I+ +DD Sbjct: 492 MEKQNEEMKKQMDDLRSQLKENK-DYQSQL---ENM---KLIQEENDDLKERIGDMSNLS 544 Query: 1137 XXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQE----CYTKIIQLETLNTELTGHDVVN 1192 LK ++ + E+ +L++Q L + +E ++K+I + ++ + + Sbjct: 545 DQILELK-KKLNDSENEKEILRKQIDNLCKDDEEEDVPTFSKVISDLKVENQILKKKISD 603 Query: 1193 QEQINQ----LKSKLEQ---LNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQ 1245 EQI++ LK ++ + + END L ++ L+++I + +R EI E L + Sbjct: 604 SEQISKENEDLKKQINEYIDIENENDELKDEISTLQNNIQK-ITERNEEI-EKQNDDLKK 661 Query: 1246 READFQKTEHELRVQLSAFESKYEQL-LDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEE 1304 D H L ++ + +L ++ ++ +E N ++ + + + + ++ Sbjct: 662 NNDDLHVKIHNLEQKVDNLTNLNNELTINQMKYEDIKEENDLLKNKSASPVSATPRTQQN 721 Query: 1305 HLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQE 1364 ++ LQ + ++ +IEIL I +K+ L+ EN+ M + Sbjct: 722 KIQQLQMRNDELKTEIEILHQTI--DKLTSARIKDNDSKTVDNEIDLLKKENERLNAMLD 779 Query: 1365 QSIL-------NINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIY 1417 S + I+E + K + + + K+ + + L+ ++ ++ Sbjct: 780 DSSMQIIMLQQEIDENKSNSLKQENEKLQEQIEELQKHSPSPKKLQQENNSLKQENEKLQ 839 Query: 1418 QKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQ 1477 ++ E T+ + + EN Q L E +++D E +S + L+ + E N+ Sbjct: 840 EEIEELQNTVDKLQN--ENNLQSLQEENDKLQDEIEELQSTVEKLQQENEELKNNKPIYS 897 Query: 1478 KESEIERVKLIEELNVKITESVSLNKQVAELNKA---LEEEVAKTNEMQTALENQEIEIV 1534 + KL E N E+ L +Q+ EL L+ N++Q + + EI Sbjct: 898 PSPK----KLQNENNSLKQENEKLQEQIEELQNTIDKLQNSNKSPNKLQQENNSLKQEIE 953 Query: 1535 TLNDEITNLQNMVRASSSKIQ---KHVSFASDTKQGRDEQLDNTMNK 1578 L +EI S +K+Q + + ++ Q + E+L NT+ K Sbjct: 954 NLKEEIEQNNKSKSYSPNKLQNENESLKQENEKLQEQIEELQNTVEK 1000 >UniRef50_UPI0000DB6B83 Cluster: PREDICTED: similar to lava lamp CG6450-PC; n=1; Apis mellifera|Rep: PREDICTED: similar to lava lamp CG6450-PC - Apis mellifera Length = 3357 Score = 193 bits (471), Expect = 3e-47 Identities = 261/1195 (21%), Positives = 530/1195 (44%), Gaps = 129/1195 (10%) Query: 445 KDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQ---EQLKQE---LNDEIKDVNV 498 +D + + E Q + S+ G E N I +++ E+LKQ L +E K Sbjct: 334 RDPTVDEFVAELQDKIVNISMHGNGAIVEKDNRIIELENLVEELKQSNKFLEEESKAELQ 393 Query: 499 KDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIV 558 K + + EE ++ D + +K + + K+ KL + + I K+SD+N E+V Sbjct: 394 KQVADLTLKNEEYSNKITDLENFVHK-LEEEKNEITAKLPE-EGIIKEDEKISDTNAELV 451 Query: 559 RLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLA-------ET 611 RL +VA LEEEKGNLQL LVD+D + D ++++++E+ E Sbjct: 452 RL-------GNQVALLEEEKGNLQLSLVDFDELKASAGDWQERVVDLESKVSAQTKEIEM 504 Query: 612 RLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDAL 671 +++AI+ LE+QK DL+QELH+ +Q+ +E + A+ L +V +EIK V LEEQ++A+ Sbjct: 505 QIEAIATLENQKLDLLQELHMAKQEISSLEAENAESENL---RVTAEIKVVDLEEQLEAI 561 Query: 672 -------------SASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNY--IQE 716 + EL +E L + +LY I E +++ IQE Sbjct: 562 HRMQNESKLESSSEVNSAELIKQVETLTQENTELYNRISKFEEKGTSDTGSTESFEAIQE 621 Query: 717 NMDLTDKLEKMSAEKI--SELLAKI--NHEEQSKIQ--TQFGID-----AKIQERDLYIE 765 +D TD +E+ + +E +I N+E +KI+ TQ + K++E+ YIE Sbjct: 622 -LDKTDLVEEKGSSDTGSTESFERIPENNESMTKIELLTQENSELVIKLTKLEEQLEYIE 680 Query: 766 NIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVN 825 + K K L + I ++ L + +L ++ KQ SE + ++ + Sbjct: 681 SKSDIDLKLKIDTLELHKEIEMLSINNTDLTIEPHKL--EIETKQSEESEISKRDVDFKT 738 Query: 826 RLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANR 885 ++ +LM+ +++K++ E+ + ++ +KNQ L + +L+ + ++ + +V K + Sbjct: 739 QVNILMEEKDLLQKEVKELRNSLEQWHEKNQDL--QINDLRTKIEELLRENEEVVTKMSE 796 Query: 886 TDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEI-EDLEIEFNTQIESAIRDKK 944 ++ + K + L L ++ E Q +Q+KK++ E ++I + ++ + Sbjct: 797 ---LKTSNQKLEENTLKLTEKLDKLNLEKQN--IQEKKQLDEQIDIPLEKSDQELLKTPQ 851 Query: 945 VLNEKYEKNIE--YVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPD 1002 L+E + E V LE ++++ KN I +EE+ K+ L +K ++++ Q D Sbjct: 852 -LDEPLSQQTESTIVASLEQEIEKCKNLIAEQTGLIEEM-KIKLVNKEKELEEKSQQIVD 909 Query: 1003 ------YTEQYINEINKLNALLKQ---KDEEIIALNQKINNAQVSY-------MSMVSDY 1046 E NE+ ++ + +++ K E+ +K+ + V++ +S++S+ Sbjct: 910 CERSGKKVETLENELREMFSTIEEWRYKCNEMEEKMEKLEDTTVTFESKLERQISIISEK 969 Query: 1047 ESKLAQFTTKLENMEEEMQRVSKQL------LDSKQHN-EELQILVREQDDQIKELKETK 1099 E+++ + +E ++E+Q +L +DS Q ++L++E+D I + Sbjct: 970 ENEIIRLKETIEEKDQELQAKYTELQNKMITIDSLQDEFNNCKMLIQEKDTSITSMTNEV 1029 Query: 1100 LTFEMNIPKTEGMIIS--STIEPMSD---------DANNVDXXXXXXXXXXXXLK----- 1143 + E I S I +SD D N++ L+ Sbjct: 1030 ANLNNLVKSKEEEIYSLRKNITELSDKLEQSIPVKDYNDLMEKLKDKNMIVDELECRINA 1089 Query: 1144 -VQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSK 1202 +E ++ L +Q+ + +L E +++ L T L V +++ +++ + Sbjct: 1090 TTKENSNLSEKVKNLSQQNNDIQNQLTEKQRELVDLITTKDHLEAEIVETKDEKGEVERR 1149 Query: 1203 LEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLS 1262 + +L T DN V +L++ + S Q + +L +H + Q+ E + +L+ Sbjct: 1150 VWELQTIIDNNTKFVNDLQTELRSNYKQ----MEQLKSKHAEDTQLQNQRLETVIE-ELT 1204 Query: 1263 AFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEI 1322 A + E L + ++ + + VT E +L++K+ D E+ L++ +EK + +++ Sbjct: 1205 AKMRECEILKEELEQK-ERLIGRNVTEEAKVALESKVADLEKRLKDSEEKVQLQLEKMKK 1263 Query: 1323 LRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQ---------EQSILNINEE 1373 + + ++ + + + KQ+Q + I ++ E+ Sbjct: 1264 IAANLKKKTAVCQELETRVAELEEKWTTEKDEKEAKNKQIQDVEITIREKDNRIADLEEK 1323 Query: 1374 NAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQ---KTHEYTITLTQR 1430 AQ + S ++ + K+ LT Q+ + EI + T LT Sbjct: 1324 LAQSRNESSQASKNIERLTTDSSNLKEKMASLTQQIAEMEEEIVKLRVDLESSTTDLTLE 1383 Query: 1431 NDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEE 1490 + + V + Y +++ ++ EL ++ K E + + M+ E +E + LI + Sbjct: 1384 KESRQLVSSEYESYRRQVVQENERRQLELDEMKEKARELSVRMQVMEAE-YVEHLTLIND 1442 Query: 1491 LNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALEN-QEIEIVTLNDEITNLQ 1544 L K + L+KQ A +N+ LE ++ E + LE ++ +V E T Q Sbjct: 1443 L--KAENGLLLSKQ-AHINEKLETVEKESEERRLLLEQLEKAAVVNTRAEATQTQ 1494 Score = 164 bits (399), Expect = 2e-38 Identities = 261/1253 (20%), Positives = 553/1253 (44%), Gaps = 130/1253 (10%) Query: 168 METTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIA 227 +ETTI+DLQE + EKD +IE+K KA T EDTK +M MQE+F+ Sbjct: 160 IETTIMDLQENLKEKDSVIESKTKAVTLMSADLSKRGKTTLDTLEDTKDEMRTMQEHFVL 219 Query: 228 MEAEWKDEKQRLLKDIESKDVRISSLEEA----NKLLEAARFE--ISLEHSKLAQELEQX 281 +E K++ + LL ++ +D +I LE++ K + + S++ S+ + Sbjct: 220 LETSLKNKNENLLMQLQERDDKIVELEDSVDRFRKQINEQKLSETASVDFSRSTMDTLVE 279 Query: 282 XXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHL--NCQIR 339 L + S++ + E + L++A E K+E + + + Sbjct: 280 TKEAMKSMQENFVLMESSLKAKNDNLLEQLKDYELKLAEANERVFKLESGIGIVRDPTVD 339 Query: 340 QTNKELENKLATMGTESK-AVSSPSKKGSPLIS-----RKSGRNTASKMKSP-WSQLSSE 392 + EL++K+ + A+ + L + ++S + + K+ Q++ Sbjct: 340 EFVAELQDKIVNISMHGNGAIVEKDNRIIELENLVEELKQSNKFLEEESKAELQKQVADL 399 Query: 393 TL-NQDTDKKIN--KNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLI 449 TL N++ KI +N + KLE + L ++ + ++ G + Sbjct: 400 TLKNEEYSNKITDLENFVHKLEEEKNEITAKLPEEGIIKEDEKISDTNAELVRLGNQVAL 459 Query: 450 AQLQLEHQQ--HMEGPSL-IHVGTNTEDVNEI-AKVQEQLKQELNDEIKDV----NVK-D 500 + + + Q ++ L G E V ++ +KV Q K E+ +I+ + N K D Sbjct: 460 LEEEKGNLQLSLVDFDELKASAGDWQERVVDLESKVSAQTK-EIEMQIEAIATLENQKLD 518 Query: 501 LIEKLKSAEEQITQLNDEIDAANKNM-----IKV----KSNHKLKLKQMQKTIDNFSKVS 551 L+++L A+++I+ L E +A ++N+ IKV + + Q + +++ S+V+ Sbjct: 519 LLQELHMAKQEISSLEAE-NAESENLRVTAEIKVVDLEEQLEAIHRMQNESKLESSSEVN 577 Query: 552 DSN--KEIVRLTEELHHLSQKVAELEE----EKGNLQLH--LVDYDSGRMIE---SDVYK 600 + K++ LT+E L ++++ EE + G+ + + + D ++E S Sbjct: 578 SAELIKQVETLTQENTELYNRISKFEEKGTSDTGSTESFEAIQELDKTDLVEEKGSSDTG 637 Query: 601 KMIEMENLAETR--LKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSE 658 E + E + I LL + +LV +L L+++ + +E K +DI + + Sbjct: 638 STESFERIPENNESMTKIELLTQENSELVIKLTKLEEQLEYIESK-SDI------DLKLK 690 Query: 659 IKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQ-NYIQEN 717 I ++ L ++I+ LS + +L + L+++ +Q ++ E K D+ K Q N + E Sbjct: 691 IDTLELHKEIEMLSINNTDLTIEPHKLEIETKQ----SEESEISKRDVDFKTQVNILMEE 746 Query: 718 MDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSR 777 DL K K + + HE+ +Q + KI+E E + +++S+ K+ Sbjct: 747 KDLLQKEVKELRNSLEQW-----HEKNQDLQIN-DLRTKIEELLRENEEVVTKMSELKTS 800 Query: 778 ICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVV 837 +LEE+ + ++ L + +QEK++ + I ++ L D + Sbjct: 801 NQKLEENTLKLTEKLDKLNLEKQN----IQEKKQLDEQIDIPLEKSDQELLKTPQLDEPL 856 Query: 838 EKQLLE--IEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTK 895 +Q + +E++K ++ E+ ++ + L EK+ + E K Sbjct: 857 SQQTESTIVASLEQEIEKCKNLIAEQTGLIEEMKIKLVNKEKELEEKSQQIVDCERSGKK 916 Query: 896 YQT---QLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIE---SAIRDKKVLNEK 949 +T +LR++ S ++ ++ + +K +++ED + F +++E S I +K+ + Sbjct: 917 VETLENELREMFSTIEEWRYKCNEM-EEKMEKLEDTTVTFESKLERQISIISEKENEIIR 975 Query: 950 YEKNIEYVTQ-LEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYI 1008 ++ IE Q L+A+ E +N + ++ +E N N +++ +Q++ T T Sbjct: 976 LKETIEEKDQELQAKYTELQNKMITIDSLQDEFN--NCKML---IQEKDTSITSMT---- 1026 Query: 1009 NEINKLNALLKQKDEEIIALNQKIN--NAQVSYMSMVSDYESKLAQFTTK---LENME-- 1061 NE+ LN L+K K+EEI +L + I + ++ V DY + + K ++ +E Sbjct: 1027 NEVANLNNLVKSKEEEIYSLRKNITELSDKLEQSIPVKDYNDLMEKLKDKNMIVDELECR 1086 Query: 1062 -----EEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKT---EGMI 1113 +E +S+++ + Q N ++Q + E+ ++ +L TK E I +T +G + Sbjct: 1087 INATTKENSNLSEKVKNLSQQNNDIQNQLTEKQRELVDLITTKDHLEAEIVETKDEKGEV 1146 Query: 1114 ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYT 1173 E + NN K Q E+ + Q Q+ +L T ++E Sbjct: 1147 ERRVWELQTIIDNNTKFVNDLQTELRSNYK-QMEQLKSKHAEDTQLQNQRLETVIEELTA 1205 Query: 1174 KIIQLETLNTE------LTGHDVVNQEQI----------NQLKSKLEQLNTENDNLLSTV 1217 K+ + E L E L G +V + ++ +LK E++ + + + Sbjct: 1206 KMRECEILKEELEQKERLIGRNVTEEAKVALESKVADLEKRLKDSEEKVQLQLEKMKKIA 1265 Query: 1218 AEL--RSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSV 1275 A L ++++ ++ R E+ E W ++EA K ++ + + +++ L + + Sbjct: 1266 ANLKKKTAVCQELETRVAELEEKWTTEKDEKEAK-NKQIQDVEITIREKDNRIADLEEKL 1324 Query: 1276 QSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIE 1328 S E + +E++T+ + L++K + +L ++ A++ +I LR ++E Sbjct: 1325 AQSRNESSQASKNIERLTTDSSNLKEK---MASLTQQIAEMEEEIVKLRVDLE 1374 Score = 144 bits (349), Expect = 2e-32 Identities = 279/1430 (19%), Positives = 596/1430 (41%), Gaps = 119/1430 (8%) Query: 212 EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271 E TK E I A +++K LL+++ ISSLE N E R ++ Sbjct: 492 ESKVSAQTKEIEMQIEAIATLENQKLDLLQELHMAKQEISSLEAENAESENLRVTAEIKV 551 Query: 272 SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELL 331 L ++LE + + E E +E+ N EL K++E L Sbjct: 552 VDLEEQLE--------------AIHRMQNESKLESSSEV---------NSAELIKQVETL 588 Query: 332 EHLNCQIRQTNKELENK--LATMGTES-KAVSSPSKKGSPLISRKSGRNTASKMKSPWSQ 388 N ++ + E K T TES +A+ K + L+ K +T S Sbjct: 589 TQENTELYNRISKFEEKGTSDTGSTESFEAIQELDK--TDLVEEKGSSDTGSTESFERIP 646 Query: 389 LSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTL 448 ++E++ T ++ E ++L + + L + L EY+ S+ D Sbjct: 647 ENNESM---TKIELLTQENSELVIKLTKLEEQL---EYIESKSDIDLKLKIDTLE-LHKE 699 Query: 449 IAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEK-LKS 507 I L + + P + + T + +EI+K K ++N +++ KDL++K +K Sbjct: 700 IEMLSINNTDLTIEPHKLEIETKQSEESEISKRDVDFKTQVNILMEE---KDLLQKEVKE 756 Query: 508 AEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEI----VRLTEE 563 + Q +++ N ++ K L++ ++ + S++ SN+++ ++LTE+ Sbjct: 757 LRNSLEQWHEKNQDLQINDLRTKIEE--LLRENEEVVTKMSELKTSNQKLEENTLKLTEK 814 Query: 564 LHHLSQKVAELEEEKGNLQL-HLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQ 622 L L+ + ++E+K QL +D + + + ++ +T ++ LE Q Sbjct: 815 LDKLNLEKQNIQEKK---QLDEQIDIPLEKSDQELLKTPQLDEPLSQQTESTIVASLE-Q 870 Query: 623 KFDLVQELHILQQK--YDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELAL 680 + + + L I +Q +E++ KL + + ++ + ++++ L +E+ Sbjct: 871 EIEKCKNL-IAEQTGLIEEMKIKLVNKEKELEEKSQQIVDCERSGKKVETLENELREMFS 929 Query: 681 VIENLKLDKEQLYGTIKDLENDKEDIMNKLQ---NYIQENMDLTDKLEKMSAEKISELLA 737 IE + ++ ++ LE+ +KL+ + I E + +L++ EK EL A Sbjct: 930 TIEEWRYKCNEMEEKMEKLEDTTVTFESKLERQISIISEKENEIIRLKETIEEKDQELQA 989 Query: 738 KINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLER 797 K E Q+K+ T + + + I+ ++ ++ + + L + E+ YSL + Sbjct: 990 KYT-ELQNKMITIDSLQDEFNNCKMLIQEKDTSITSMTNEVANLNNLVKSKEEEIYSLRK 1048 Query: 798 KADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQI 857 +L L E+ +Y ++L ++ ++ + +E ++ EN L +K + Sbjct: 1049 NITELSDKL-EQSIPVKDYNDLMEKLKDKNMIVDE----LECRINATTKENSNLSEKVKN 1103 Query: 858 LLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTL 917 L ++N ++Q L++ Q+ LV+ D E+E + +D + ++R E QT+ Sbjct: 1104 LSQQNNDIQNQLTEKQRE---LVDLITTKDHLEAEI----VETKDEKGEVERRVWELQTI 1156 Query: 918 IVQKKKEIEDLEIEFNT------QIESA-IRDKKVLNEKYEKNIEYVTQLEAQLQEYKNN 970 I K + DL+ E + Q++S D ++ N++ E IE +T + + K Sbjct: 1157 IDNNTKFVNDLQTELRSNYKQMEQLKSKHAEDTQLQNQRLETVIEELTAKMRECEILKEE 1216 Query: 971 IEN----LNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEII 1026 +E + NV E K+ LE ++K+ S + + + ++ K+ A LK+K Sbjct: 1217 LEQKERLIGRNVTEEAKVALESKVADLEKRLKDSEEKVQLQLEKMKKIAANLKKKTAVCQ 1276 Query: 1027 ALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVS---KQLLDSKQHNEELQI 1083 L ++ + + + + E+K Q + E+ R++ ++L S+ + + Sbjct: 1277 ELETRVAELEEKWTTEKDEKEAKNKQIQDVEITIREKDNRIADLEEKLAQSRNESSQASK 1336 Query: 1084 LVREQDDQIKELKETKLTFEMNIPKTEGMIISSTI--EPMSDDANNVDXXXXXXXXXXXX 1141 + LKE + I + E I+ + E + D Sbjct: 1337 NIERLTTDSSNLKEKMASLTQQIAEMEEEIVKLRVDLESSTTDLTLEKESRQLVSSEYES 1396 Query: 1142 LK---VQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHD---VVNQEQ 1195 + VQE E E ++E++ +L+ +Q + ++ TL +L + + Q Sbjct: 1397 YRRQVVQENERRQLELDEMKEKARELSVRMQVMEAEYVEHLTLINDLKAENGLLLSKQAH 1456 Query: 1196 INQLKSKLEQLNTENDNLLSTV--AELRSSISSAVDQRGFEIAELWKQHLAQREADFQKT 1253 IN+ +E+ + E LL + A + ++ + A +G E E+ + + Q Sbjct: 1457 INEKLETVEKESEERRLLLEQLEKAAVVNTRAEATQTQGEE--EMANEDEGKTSGALQHC 1514 Query: 1254 EH--ELRVQLSAFESKYEQLLDSVQSSTQEETNKI---VTMEQVTSLQNKLQDKEEHLRN 1308 H + + + A E+K ++ +++ E N I V M + + + R Sbjct: 1515 THCEQCQTLVQALEAKLQEREAEIENLDNELANSIGNFVQMRESLRFNDLMNQTGMRNRT 1574 Query: 1309 LQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSIL 1368 L++ Y D++ Q L S E+ KV+ LR N ++ Q + ++ Sbjct: 1575 LEDPYNDLLFQYNSLASSHEEVKVSL-EKASRENEELRGTVDQLRVTNDTF-QERITTLE 1632 Query: 1369 NINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQL-----ELKDSEIYQKTHEY 1423 N++ N+ L K + + + EL +L LK E ++ E Sbjct: 1633 NVDALNSDLVKKWEERERELLNARQELEIVQRRGDELERRLNAQAESLKSVEARREAAEK 1692 Query: 1424 TITLTQRN--DEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESE 1481 ++ T+ + E E++R E++++DL E+EL R + +A + + + Sbjct: 1693 SLRDTKESLEREIESLRMDKDSSERKMKDL----ETELDAWRSRESFDAPPRDNAPQLFD 1748 Query: 1482 IERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEIT 1541 R+ + +E ++ ++V L LEE A+ + + + + TL++E Sbjct: 1749 ASRI-FGSAPSPLDSEPLADREEVKRLRSLLEEREAQCSNLTQEVYQLQ---GTLSEERR 1804 Query: 1542 NLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDL 1591 ++ + +AS ++ ++ A + +++Q++ +++ EL ++ R E +L Sbjct: 1805 LIEGL-KASQKELSTNLERAERSVAEKEKQVE-SLDAELRNSTIRMEDEL 1852 Score = 141 bits (342), Expect = 1e-31 Identities = 226/1131 (19%), Positives = 505/1131 (44%), Gaps = 108/1131 (9%) Query: 473 EDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSN 532 + +NE K+ E + + D V+ E +KS +E + + A N N+++ + Sbjct: 254 KQINE-QKLSETASVDFSRSTMDTLVETK-EAMKSMQENFVLMESSLKAKNDNLLEQLKD 311 Query: 533 HKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGR 592 ++LKL + + + +S IVR + + VAEL+++ N+ +H +G Sbjct: 312 YELKLAEANERVFKL----ESGIGIVRDPT----VDEFVAELQDKIVNISMH----GNGA 359 Query: 593 MIESDVYKKMIEMENLAETRLKAISLLESQ-KFDLVQELHILQQKYDEVEDKLADISQLQ 651 ++E D ++IE+ENL E ++ LE + K +L +++ L K +E +K+ D+ Sbjct: 360 IVEKD--NRIIELENLVEELKQSNKFLEEESKAELQKQVADLTLKNEEYSNKITDLENF- 416 Query: 652 SDQVCSEIKSVH-LEEQIDALSASKKELALVIENLKL-----DKEQLYGTIKDLENDKED 705 VH LEE+ + ++A E ++ E+ K+ + +L + LE +K + Sbjct: 417 ----------VHKLEEEKNEITAKLPEEGIIKEDEKISDTNAELVRLGNQVALLEEEKGN 466 Query: 706 IMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIE 765 + L ++ + D E++ +L +K++ + +I+ Q A ++ + L Sbjct: 467 LQLSLVDFDELKASAGD-----WQERVVDLESKVS-AQTKEIEMQIEAIATLENQKL--- 517 Query: 766 NIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVN 825 ++ EL K I LE A E+ R + E K L L+ + +E ++ VN Sbjct: 518 DLLQELHMAKQEISSLEAENAESENLRVTAEIKVVDLEEQLEAIHRMQNESKLESSSEVN 577 Query: 826 RLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANR 885 A L+ + ++ E+ + + ++K ++ + ++ ++ + LVE+ Sbjct: 578 S-AELIKQVETLTQENTELYNRISKFEEKGTSDTGSTESFE-AIQELDK--TDLVEEKGS 633 Query: 886 TDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLE-IEFNTQIESAIR-DK 943 +D +ES + + + + ++ +T E+ L+++ K E LE IE + I+ ++ D Sbjct: 634 SDTGSTESFERIPENNESMTKIELLTQENSELVIKLTKLEEQLEYIESKSDIDLKLKIDT 693 Query: 944 KVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNK--------MNLELIDKH-VQ 994 L+++ E + + + ++ +K IE E++K +N+ + +K +Q Sbjct: 694 LELHKEIE--MLSINNTDLTIEPHKLEIETKQSEESEISKRDVDFKTQVNILMEEKDLLQ 751 Query: 995 KQQTQSPDYTEQYINEINKLNAL-LKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQF 1053 K+ + + EQ+ + L L+ K EE++ N+++ V+ MS + KL + Sbjct: 752 KEVKELRNSLEQWHEKNQDLQINDLRTKIEELLRENEEV----VTKMSELKTSNQKLEEN 807 Query: 1054 TTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMI 1113 T KL +++ + + + KQ +E++ I + + D +EL +T E +TE I Sbjct: 808 TLKLTEKLDKLNLEKQNIQEKKQLDEQIDIPLEKSD---QELLKTPQLDEPLSQQTESTI 864 Query: 1114 ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYT 1173 ++S +E + N+ +K+ +E+ ++E+S ++ +C Sbjct: 865 VAS-LEQEIEKCKNL-IAEQTGLIEEMKIKLVNKEKELEEKS----------QQIVDCER 912 Query: 1174 KIIQLETLNTELTGHDVVNQE---QINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQ 1230 ++ETL EL +E + N+++ K+E+L D ++ ++L I S + + Sbjct: 913 SGKKVETLENELREMFSTIEEWRYKCNEMEEKMEKL---EDTTVTFESKLERQI-SIISE 968 Query: 1231 RGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTM- 1289 + EI L K+ + +++ + Q EL+ ++ +S ++ ++ + QE+ I +M Sbjct: 969 KENEIIRL-KETIEEKDQELQAKYTELQNKMITIDSLQDE-FNNCKMLIQEKDTSITSMT 1026 Query: 1290 EQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXX 1349 +V +L N ++ KEE + +L++ ++ +++E + + Sbjct: 1027 NEVANLNNLVKSKEEEIYSLRKNITELSDKLEQSIPVKDYNDLMEKLKDKNMIVDELECR 1086 Query: 1350 XDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQL 1409 + T+ S + E+ + N++++N ++ + EA+++E + Sbjct: 1087 INATTKENS--NLSEK-VKNLSQQNNDIQNQLTEKQRELVDLITTKDHLEAEIVETKDE- 1142 Query: 1410 ELKDSEIYQKTHEYTITLTQRNDEFEN-VRQQLVEYEKRIEDLTYEKESELAILRLKMHE 1468 E+ ++ E T+ N +F N ++ +L K++E L + + + ++ Sbjct: 1143 ---KGEVERRVWELQ-TIIDNNTKFVNDLQTELRSNYKQMEQLKSKHAEDTQLQNQRLET 1198 Query: 1469 NANHYETMQKESEI--ERVKLIEEL---NVKITESVSLNKQVAELNKALEEEVAKTNEMQ 1523 +E EI E ++ E L NV V+L +VA+L K L++ K +Q Sbjct: 1199 VIEELTAKMRECEILKEELEQKERLIGRNVTEEAKVALESKVADLEKRLKDSEEK---VQ 1255 Query: 1524 TALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDN 1574 LE + L + Q + +++++ + D K+ +++Q+ + Sbjct: 1256 LQLEKMKKIAANLKKKTAVCQEL-ETRVAELEEKWTTEKDEKEAKNKQIQD 1305 Score = 135 bits (327), Expect = 8e-30 Identities = 294/1479 (19%), Positives = 602/1479 (40%), Gaps = 151/1479 (10%) Query: 212 EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISS-LEEANKLLEAARFEISLE 270 E+ + Q + + + ++ +E+ RL++ +++ +S+ LE A + A E +E Sbjct: 1779 EEREAQCSNLTQEVYQLQGTLSEER-RLIEGLKASQKELSTNLERAER--SVAEKEKQVE 1835 Query: 271 HSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIEL 330 L EL + ++ ++E +LE A + E ++ L Sbjct: 1836 --SLDAELRNSTIRMEDELRESLSAKDEQLKELNARLDSVKE--TLEEA-LVERDRQHSL 1890 Query: 331 LEHLNCQIRQTNKELENKL---ATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWS 387 L QI EL N A E + +S ++ + + ++K + Sbjct: 1891 LRSYESQINDLEMELRNSTDLDALQDLEKRVLSLTKERDLLQLQVNDLTRSMEELKDSIN 1950 Query: 388 Q-LSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKD 446 + +SE ++ + IA L ++ + DK V + T ++ Sbjct: 1951 RGRNSEMEKVGRERDEARETIASLSRALEEARERQSDKATVTDDTSTKESLERRASKIEE 2010 Query: 447 TLIAQLQLEHQQHMEGPSLIHVGTNTEDV---NEIAKVQEQLKQELNDEIKDVNVKDLIE 503 ++ L + + + I G NTED +E A L +++ V DL + Sbjct: 2011 RSVS-LDVGEMEKINVDEEIW-GWNTEDAQLDSEQAMASTILIPSTEIQLR-AKVDDLQD 2067 Query: 504 KLKSAEEQITQLNDEIDAA---NKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRL 560 ++K E + ++ +E AA N M+K +K + + +Q+ + K+ + + L Sbjct: 2068 QVKDLERERARMGEENKAAQLRNAKMLKKLKEYKAQAESLQQQL----KIQKTAADFYGL 2123 Query: 561 TEELHHLSQKVAELEEEKGNLQLHLVDYDSGR---MIESDVYKKMIEMENLAETRLKAIS 617 + EL+ + G L+ +L + R + E + K +++ A R + Sbjct: 2124 DSAIEE------ELKSQIGKLEKNLNEVKEERRNTVAEKEALMKRLDVVVSANERY--ME 2175 Query: 618 LLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKE 677 + E Q D+ +L+ + E+ DK+ + + D S + V + + A++++ Sbjct: 2176 MKERQDMDM----EVLRIRNKELSDKVEILDKRLQD---STFRLVEDDTSSEQKVATQEQ 2228 Query: 678 LALVIENLKLDKE-QLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELL 736 + E L KE L K + + +D+ ++++ EN L LE+ K+S L Sbjct: 2229 ASSSREKRSLPKEADLESLSKRYKEEMDDLKDEMEALATENEQLQHFLEEQKI-KLSALE 2287 Query: 737 AKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLE 796 +K + EE IQ ++ KI E + E + + E+S+ D+ ++ Sbjct: 2288 SKRSAEEDESIQIVDDLNGKISELQAVLSKSREEYDLLRKQY---EQSLMDANDQVTAMR 2344 Query: 797 RKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQ 856 + AD L K++A+ E E+V+ + +QL E EL+K + Sbjct: 2345 QNADYL------KEEAFERTAKLEMEIVD-----------LRQQLEASELNVTELRKGLE 2387 Query: 857 ILLEENQNLQISLSDMQQHYNALVEKANRTDLAESE--STKYQTQLRDLESNLKRITHEH 914 L E +++ L+D+ V N + L ++ +T+ Q ++ DL L++ EH Sbjct: 2388 DALREKSSVEERLTDLTASTEKQVSSLNASMLEVTDLLNTRIQ-EVADLRQELQKQYVEH 2446 Query: 915 QTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKY-EKNIEYVTQLEAQLQEYKNNIEN 973 + + K ++ E N +++ ++ + L + E+ E+V + ++ + Sbjct: 2447 E----EAKTRLQSTVKESNRELDEKRQEMEDLRRSFAEREKEFVER--QSVETVSALVSQ 2500 Query: 974 LNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINE--INKLNAL--LKQKDEEIIALN 1029 + + + + +E DKHV + + E NE + K N + L + +E+ L Sbjct: 2501 ATQELMQRHAIEIEERDKHV-RNLNERLSALEATANECLLEKRNNVVQLDARIQELELLR 2559 Query: 1030 QKINNAQVSYMSMVSDY---ESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVR 1086 + + + S S+ + E +LAQ +L EE ++++S + + EEL+ + Sbjct: 2560 RDLMEKESSLASVREGFASMEKQLAQRELELSEREETIRKLSLENQRCVETVEELRKRLN 2619 Query: 1087 EQDDQIKELKETKL---TFEMNIPKTEGM------IISSTIEPMSDDANNVDXXXXXXXX 1137 E + E L T E + + I+ +E ++ ++ Sbjct: 2620 ESATISANVNEYTLRVQTLEREVENMRSLLDEKEAILRKNVEEATEYREIIEKSRIELSE 2679 Query: 1138 XXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQL-ETLNTELTGHDVVN---- 1192 ++VQ+ E+ E +E+ LN+EL+ + + + LN +++ D N Sbjct: 2680 LR--MEVQKVEDLKNELLEKEERVNSLNSELEATRKALEETRQNLNEKMSLLDHSNRLLN 2737 Query: 1193 --QEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQ-H-LAQREA 1248 Q +I++L S L+Q + N++ + R Q + ++ ++ H L +A Sbjct: 2738 ERQMEIDRLSS-LQQDRRSSANMIDGLPVFRMGNGEQNLQHTIDNMQMQQRIHCLYNEKA 2796 Query: 1249 DFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNK----------IVTMEQVTSLQNK 1298 + + + + + E + L +++ +QE +K I EQ+ LQN+ Sbjct: 2797 ELESSLLVINARAEEKEKQIHALEQRIETQSQEFVSKEELHSRDRRSIQEQEQIVRLQNE 2856 Query: 1299 LQDKEEHLRNLQEKYADVINQIEILRS-----------EIEDEKVAFXXXXXXXXXXXXX 1347 L KE+ + L+ A+ +Q+ + S E+ A Sbjct: 2857 LYAKEQEINELKYIVAEKESQLSVQASMEPQSDEFELREMVQRLTAELYGKEEEVKHTKL 2916 Query: 1348 XXXDLRTEN---QSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLE 1404 +L+ E Q +++ EQ+ + + NA+ ++ R+ + E ++ E Sbjct: 2917 TIVELQREVSRLQEFERFSEQTREAVQKLNAEKEQ---IRLEGEEFLERRLKEKEMEIDE 2973 Query: 1405 LTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEY---EKRIEDLTYEKESELAI 1461 + L +++ +I + L+ N + E+++ QL E E+R +D +E +L Sbjct: 2974 IKRNLAMENQKILDE-------LSFNNRDIESLKSQLTELSTTEQRTKDELRRREEDL-- 3024 Query: 1462 LRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNE 1521 LR+ N++ E ++ +E+ K E N+KI S + ++ EL EE + E Sbjct: 3025 LRV----NSDLAEKKRRLAELSITKDAELHNLKIQISEK-DARIEELVSLYEEGEKRFTE 3079 Query: 1522 MQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELL 1581 ++ L +EIEI +L + + + + ++K VS + + + + +K Sbjct: 3080 LKNTLSAREIEINSLKTLLEDKVKEYQLIQNVLKKDVSVLDTSTSTTNPNTETSDDKSKT 3139 Query: 1582 DAVPRAELDLAMYMLHQRDVRCXXXXXXXXXXXXXRDTL 1620 ELDLA+YMLHQRDVRC RDTL Sbjct: 3140 ST--SQELDLALYMLHQRDVRCEELTHELMQLLEERDTL 3176 Score = 112 bits (270), Expect = 7e-23 Identities = 290/1524 (19%), Positives = 611/1524 (40%), Gaps = 151/1524 (9%) Query: 143 DVTHLSNTIKEKDNAL-----SVLQVKMKIMETTIL----DLQEKINEKDQII---EAKN 190 +V +L+N +K K+ + ++ ++ K+ ++ + DL EK+ +K+ I+ E + Sbjct: 1028 EVANLNNLVKSKEEEIYSLRKNITELSDKLEQSIPVKDYNDLMEKLKDKNMIVDELECRI 1087 Query: 191 KATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAM-------EAE---WKDEKQRLL 240 ATT D + Q+T+ Q + + EAE KDEK + Sbjct: 1088 NATTKENSNLSEKVKNLSQQNNDIQNQLTEKQRELVDLITTKDHLEAEIVETKDEKGEVE 1147 Query: 241 KDI-ESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQS 299 + + E + + ++ + N L R ++ E L + Sbjct: 1148 RRVWELQTIIDNNTKFVNDLQTELRSNYKQMEQLKSKHAEDTQLQNQRLETVIEELTAKM 1207 Query: 300 IEPSCEE-KTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKA 358 E CE K E+E+K L N+TE K LE + + K+ E K+ + K Sbjct: 1208 RE--CEILKEELEQKERLIGRNVTEEAKVA--LESKVADLEKRLKDSEEKVQLQLEKMKK 1263 Query: 359 VSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLN 418 +++ KK + + R ++++ W T +D +K+ +I +E+ I+ + Sbjct: 1264 IAANLKKKTAVCQELETR--VAELEEKW------TTEKD-EKEAKNKQIQDVEITIREKD 1314 Query: 419 KDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEI 478 + D E +++ T + L+ + M SL E+ EI Sbjct: 1315 NRIADLEEKLAQSRNESSQASKNIERLTTDSSNLK----EKMA--SLTQQIAEMEE--EI 1366 Query: 479 AKVQEQLKQELNDEIKDVNVKDLIE-KLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKL 537 K++ L+ D + + L+ + +S Q+ Q N+ M + +++ Sbjct: 1367 VKLRVDLESSTTDLTLEKESRQLVSSEYESYRRQVVQENERRQLELDEMKEKARELSVRM 1426 Query: 538 KQMQ-KTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIES 596 + M+ + +++ + ++D E L + H+++K+ +E+E +L L + ++ + Sbjct: 1427 QVMEAEYVEHLTLINDLKAENGLLLSKQAHINEKLETVEKESEERRLLLEQLEKAAVVNT 1486 Query: 597 --DVYKKMIEMENLAETRLKAISLLE-----SQKFDLVQELHI-LQQKYDEVED------ 642 + + E E E K L+ Q LVQ L LQ++ E+E+ Sbjct: 1487 RAEATQTQGEEEMANEDEGKTSGALQHCTHCEQCQTLVQALEAKLQEREAEIENLDNELA 1546 Query: 643 -KLADISQLQSDQVCSEI------KSVHLEE-------QIDALSASKKELALVIENLKLD 688 + + Q++ +++ ++ LE+ Q ++L++S +E+ + +E + Sbjct: 1547 NSIGNFVQMRESLRFNDLMNQTGMRNRTLEDPYNDLLFQYNSLASSHEEVKVSLEKASRE 1606 Query: 689 KEQLYGTIKDLE--NDK-EDIMNKLQNYIQENMDLTDKLEKMSAEKIS-----ELLAKIN 740 E+L GT+ L ND ++ + L+N N DL K E+ E ++ E++ + Sbjct: 1607 NEELRGTVDQLRVTNDTFQERITTLENVDALNSDLVKKWEERERELLNARQELEIVQRRG 1666 Query: 741 HEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKAD 800 E + ++ Q ++ R E E L K + R ES+ + +D S ERK Sbjct: 1667 DELERRLNAQAESLKSVEARR---EAAEKSLRDTKESLEREIESLRMDKD---SSERKMK 1720 Query: 801 QLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHE---NKELQKKNQI 857 L + L + S D L D R+ ++ E ++E K+ + Sbjct: 1721 DLETELDAWRSRESFDAPPRDNAPQ----LFDASRIFGSAPSPLDSEPLADREEVKRLRS 1776 Query: 858 LLEENQNLQISLS-DMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQT 916 LLEE + +L+ ++ Q L E+ + ++ + T L E ++ + ++ Sbjct: 1777 LLEEREAQCSNLTQEVYQLQGTLSEERRLIEGLKASQKELSTNLERAERSVAEKEKQVES 1836 Query: 917 LIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQ-------LQEYKN 969 L + + +E E + + K LN + + E + + + L+ Y++ Sbjct: 1837 LDAELRNSTIRMEDELRESLSAKDEQLKELNARLDSVKETLEEALVERDRQHSLLRSYES 1896 Query: 970 NIENLNMNVEELNKMN-LELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQ-----KDE 1023 I +L M + ++ L+ ++K V T+ D + +N++ + LK ++ Sbjct: 1897 QINDLEMELRNSTDLDALQDLEKRVLSL-TKERDLLQLQVNDLTRSMEELKDSINRGRNS 1955 Query: 1024 EIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQI 1083 E+ + ++ + A+ + S+ E + + K ++ + S + SK + + Sbjct: 1956 EMEKVGRERDEARETIASLSRALEEARERQSDKATVTDDTSTKESLERRASKIEERSVSL 2015 Query: 1084 LVREQ-----DDQIK--ELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXX 1136 V E D++I ++ +L E + T ++I ST + + D Sbjct: 2016 DVGEMEKINVDEEIWGWNTEDAQLDSEQAMAST--ILIPSTEIQLRAKVD--DLQDQVKD 2071 Query: 1137 XXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQI 1196 ++ EE + Q R+ + K E + ++++ + G D +E++ Sbjct: 2072 LERERARMGEENKAAQLRNAKMLKKLKEYKAQAESLQQQLKIQKTAADFYGLDSAIEEEL 2131 Query: 1197 NQLKSKLEQ-LNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEH 1255 KLE+ LN + +TVAE A+ +R + ++++ +E E Sbjct: 2132 KSQIGKLEKNLNEVKEERRNTVAE-----KEALMKRLDVVVSANERYMEMKERQDMDME- 2185 Query: 1256 ELRVQLSAFESKYEQLLDSVQSST----QEETN---KIVTMEQVTSLQNKLQ-DKEEHLR 1307 LR++ K E L +Q ST +++T+ K+ T EQ +S + K KE L Sbjct: 2186 VLRIRNKELSDKVEILDKRLQDSTFRLVEDDTSSEQKVATQEQASSSREKRSLPKEADLE 2245 Query: 1308 NLQEKYA----DVINQIEILRSE-------IEDEKV---AFXXXXXXXXXXXXXXXXDLR 1353 +L ++Y D+ +++E L +E +E++K+ A DL Sbjct: 2246 SLSKRYKEEMDDLKDEMEALATENEQLQHFLEEQKIKLSALESKRSAEEDESIQIVDDLN 2305 Query: 1354 TENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKD 1413 + + + +S + Q ++S + + + E T +LE++ Sbjct: 2306 GKISELQAVLSKSREEYDLLRKQYEQSLMDANDQVTAMRQNADYLKEEAFERTAKLEMEI 2365 Query: 1414 SEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHY 1473 ++ Q+ + +T+ E+ ++ E+R+ DLT E +++ L M E + Sbjct: 2366 VDLRQQLEASELNVTELRKGLEDALREKSSVEERLTDLTASTEKQVSSLNASMLEVTDLL 2425 Query: 1474 ETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEI 1533 T +E R +L ++ L V E N+ L+E+ + +++ + +E E Sbjct: 2426 NTRIQEVADLRQELQKQYVEHEEAKTRLQSTVKESNRELDEKRQEMEDLRRSFAEREKEF 2485 Query: 1534 VTLNDEITNLQNMVRASSSKIQKH 1557 V T + +A+ +Q+H Sbjct: 2486 VERQSVETVSALVSQATQELMQRH 2509 Score = 111 bits (268), Expect = 1e-22 Identities = 275/1454 (18%), Positives = 600/1454 (41%), Gaps = 153/1454 (10%) Query: 143 DVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXX 202 ++ L TI+EKD L +++ TI LQ++ N +I+ K+ + T Sbjct: 972 EIIRLKETIEEKDQELQAKYTELQNKMITIDSLQDEFNNCKMLIQEKDTSITSMTNEVAN 1031 Query: 203 XXXXXXXXXED---TKQQMTKMQENF-IAMEAEWKDEKQRLLKD----IESKDVRISSLE 254 E+ ++ +T++ + ++ + ++ LKD ++ + RI++ Sbjct: 1032 LNNLVKSKEEEIYSLRKNITELSDKLEQSIPVKDYNDLMEKLKDKNMIVDELECRINATT 1091 Query: 255 EANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKG 314 + N L +S +++ + +L + L + +E +EK E+E + Sbjct: 1092 KENSNLSEKVKNLSQQNNDIQNQLTEKQRELVDLITTKDHLEAEIVETK-DEKGEVERR- 1149 Query: 315 SLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKS 374 E+ T + + + L ++R K++E +L + E + +++ +I Sbjct: 1150 VWEL--QTIIDNNTKFVNDLQTELRSNYKQME-QLKSKHAEDTQLQ--NQRLETVI---- 1200 Query: 375 GRNTASKMKSPWSQLSSETLNQDTDKKINKN--EIAK--LEMVIQSLNKDLVDKEYVISE 430 +KM+ ++ E L Q ++ I +N E AK LE + L K L D E + + Sbjct: 1201 -EELTAKMRE--CEILKEELEQ-KERLIGRNVTEEAKVALESKVADLEKRLKDSEEKV-Q 1255 Query: 431 KDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELN 490 K T + Q +LE T ++ E ++ K+ N Sbjct: 1256 LQLEKMKKIAANLKKKTAVCQ-ELE--------------TRVAELEEKWTTEKDEKEAKN 1300 Query: 491 DEIKDV--NVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFS 548 +I+DV +++ ++ EE++ Q +E A+KN+ ++ ++ LK+ ++ Sbjct: 1301 KQIQDVEITIREKDNRIADLEEKLAQSRNESSQASKNIERLTTDSS-NLKEKMASLT--Q 1357 Query: 549 KVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENL 608 ++++ +EIV+L + L +L EK + QL +Y+S Y++ + EN Sbjct: 1358 QIAEMEEEIVKLRVD---LESSTTDLTLEKESRQLVSSEYES--------YRRQVVQEN- 1405 Query: 609 AETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQI 668 E R + ++ + +L + +++ +Y E L I+ L+++ K H+ E++ Sbjct: 1406 -ERRQLELDEMKEKARELSVRMQVMEAEYVE---HLTLINDLKAENGLLLSKQAHINEKL 1461 Query: 669 DALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMS 728 + + +E L++E L +K ++N Q + +++ Sbjct: 1462 ETVEKESEERRLLLEQL----------------EKAAVVNTRAEATQTQGE--EEMANED 1503 Query: 729 AEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVM 788 K S L H EQ + Q ++AK+QER+ IEN+++EL+ ++ ES+ Sbjct: 1504 EGKTSGALQHCTHCEQCQTLVQ-ALEAKLQEREAEIENLDNELANSIGNFVQMRESL--- 1559 Query: 789 EDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHEN 848 R++ +Q G + + Y++ Q + L + H+ V+ L + EN Sbjct: 1560 ---RFN--DLMNQTGMRNRTLEDPYNDLLFQYNSLAS------SHEE-VKVSLEKASREN 1607 Query: 849 KELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLE---S 905 +EL+ L N Q ++ ++ + + + E E + +L ++ Sbjct: 1608 EELRGTVDQLRVTNDTFQERITTLENVDALNSDLVKKWEERERELLNARQELEIVQRRGD 1667 Query: 906 NLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQ 965 L+R + + + E E ES R+ + L + + + LE +L Sbjct: 1668 ELERRLNAQAESLKSVEARREAAEKSLRDTKESLEREIESLRMDKDSSERKMKDLETELD 1727 Query: 966 EYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYIN--EINKLNALLKQKDE 1023 +++ E+ + + +L D SP +E + E+ +L +LL++++ Sbjct: 1728 AWRSR-ESFDAPPRDNAP---QLFDASRIFGSAPSPLDSEPLADREEVKRLRSLLEEREA 1783 Query: 1024 EIIALNQKINNAQVSYMS---MVSDYESKLAQFTTKLENMEEEMQRVSKQL--LDSKQHN 1078 + L Q++ Q + ++ ++ + +T LE E + KQ+ LD++ N Sbjct: 1784 QCSNLTQEVYQLQGTLSEERRLIEGLKASQKELSTNLERAERSVAEKEKQVESLDAELRN 1843 Query: 1079 ------EELQILVREQDDQIKELK----ETKLTFEMNIPKTEGMIISSTIEPMSDDANNV 1128 +EL+ + +D+Q+KEL K T E + + + S + N++ Sbjct: 1844 STIRMEDELRESLSAKDEQLKELNARLDSVKETLEEALVERDRQ--HSLLRSYESQINDL 1901 Query: 1129 DXXXXXXXXXXXXLKVQEEE-EFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTG 1187 + +++ +ER +LQ Q L ++E I + E G Sbjct: 1902 EMELRNSTDLDALQDLEKRVLSLTKERDLLQLQVNDLTRSMEELKDSINRGRNSEMEKVG 1961 Query: 1188 HDVVN-QEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQR 1246 + +E I L LE+ E + +TV + +S ++++R +I E + ++ Sbjct: 1962 RERDEARETIASLSRALEEAR-ERQSDKATVTD-DTSTKESLERRASKIEE---RSVSLD 2016 Query: 1247 EADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKE-EH 1305 + +K + + E ++ S+ + +I +V LQ++++D E E Sbjct: 2017 VGEMEKINVDEEIWGWNTEDAQLDSEQAMASTILIPSTEIQLRAKVDDLQDQVKDLERER 2076 Query: 1306 LRNLQEKYADVINQIEILR--SEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQ 1363 R +E A + ++L+ E + + + D E + Q+ Sbjct: 2077 ARMGEENKAAQLRNAKMLKKLKEYKAQAESLQQQLKIQKTAADFYGLDSAIEEELKSQIG 2136 Query: 1364 EQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEY 1423 + N+NE + ++++ V A + +E+ + ++ D E+ + Sbjct: 2137 KLE-KNLNEVKEE-RRNTVAEKEALMKRLDVVVSANERYMEMKERQDM-DMEVLR----- 2188 Query: 1424 TITLTQRNDEFENVRQQLVEYEKR-IEDLTYEKESELAILRLKMHENANHYETMQKESEI 1482 I + +D+ E + ++L + R +ED + SE + + ++ ++ KE+++ Sbjct: 2189 -IRNKELSDKVEILDKRLQDSTFRLVED---DTSSEQKVATQEQASSSREKRSLPKEADL 2244 Query: 1483 ERV--KLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQ---TALENQEIEIV-TL 1536 E + + EE++ E +L + +L LEE+ K + ++ +A E++ I+IV L Sbjct: 2245 ESLSKRYKEEMDDLKDEMEALATENEQLQHFLEEQKIKLSALESKRSAEEDESIQIVDDL 2304 Query: 1537 NDEITNLQNMVRAS 1550 N +I+ LQ ++ S Sbjct: 2305 NGKISELQAVLSKS 2318 Score = 101 bits (243), Expect = 1e-19 Identities = 186/978 (19%), Positives = 386/978 (39%), Gaps = 83/978 (8%) Query: 638 DEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELA----LVIENLKLDKEQLY 693 D E+ + DISQ ++ + S + L E A KE++ V E ++ ++QL Sbjct: 67 DTPEENIDDISQAKTAKAKSTLLQKKLAENRKAFEQRNKEISETKRAVEEKVEAIRQQLE 126 Query: 694 G---TIKDLENDK------------EDIMNKLQ-----NYIQENMDLTDKLEKMSAEKIS 733 T+ + D+ DIM+ +Q +QEN+ D + + + ++ Sbjct: 127 EKDVTVMAFQKDQISITAVKPVMITSDIMSPIQIETTIMDLQENLKEKDSVIESKTKAVT 186 Query: 734 ELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESEL-SKYKSRICRLEESIAVMEDRR 792 + A ++ ++ + T +++ + +E+ L +K ++ + +L+E +D+ Sbjct: 187 LMSADLSKRGKTTLDTLEDTKDEMRTMQEHFVLLETSLKNKNENLLMQLQE----RDDKI 242 Query: 793 YSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQ 852 LE D+ + E++ SE T D + + L++ ++ L+ Sbjct: 243 VELEDSVDRFRKQINEQK--LSE-TASVDFSRSTMDTLVETKEAMKSMQENFVLMESSLK 299 Query: 853 KKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITH 912 KN LLE+ ++ ++ L++ + L + + + +L+ + I+ Sbjct: 300 AKNDNLLEQLKDYELKLAEANERVFKL-----ESGIGIVRDPTVDEFVAELQDKIVNISM 354 Query: 913 EHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIE-YVTQLEAQLQEYKNNI 971 IV+K I IE +E + K L E+ + ++ V L + +EY N I Sbjct: 355 HGNGAIVEKDNRI----IELENLVEELKQSNKFLEEESKAELQKQVADLTLKNEEYSNKI 410 Query: 972 ENLNMNV----EELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIA 1027 +L V EE N++ +L ++ + K+ + D + + N++ L ++K ++ Sbjct: 411 TDLENFVHKLEEEKNEITAKLPEEGIIKEDEKISDTNAELVRLGNQVALLEEEKGNLQLS 470 Query: 1028 L--NQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILV 1085 L ++ + + V D ESK++ T ++E E + + Q LD Q + + Sbjct: 471 LVDFDELKASAGDWQERVVDLESKVSAQTKEIEMQIEAIATLENQKLDLLQELHMAKQEI 530 Query: 1086 REQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLK-- 1143 + + E + ++T E+ + E + I M +++ ++ Sbjct: 531 SSLEAENAESENLRVTAEIKVVDLEEQL--EAIHRMQNESKLESSSEVNSAELIKQVETL 588 Query: 1144 VQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLE--TLNTELTGHDVVNQEQI----- 1196 QE E S +E+ +T E + I +L+ L E D + E Sbjct: 589 TQENTELYNRISKFEEKGTS-DTGSTESFEAIQELDKTDLVEEKGSSDTGSTESFERIPE 647 Query: 1197 -NQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEI---AELWKQHLAQREADFQK 1252 N+ +K+E L EN L+ + +L + + ++ + + H Sbjct: 648 NNESMTKIELLTQENSELVIKLTKLEEQLEYIESKSDIDLKLKIDTLELHKEIEMLSINN 707 Query: 1253 TEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEK 1312 T+ + E+K + + + +T + ME+ LQ ++++ L EK Sbjct: 708 TDLTIEPHKLEIETKQSEESEISKRDVDFKTQVNILMEEKDLLQKEVKELRNSLEQWHEK 767 Query: 1313 YADVINQIEILRSEIED-----EKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSI 1367 D+ QI LR++IE+ E+V TE +++Q+I Sbjct: 768 NQDL--QINDLRTKIEELLRENEEVVTKMSELKTSNQKLEENTLKLTEKLDKLNLEKQNI 825 Query: 1368 LNINEENAQ----LKKSSXXXXXXXXXXXXRVNDAEAKVL-ELTHQLELKDSEIYQKT-- 1420 + + Q L+KS E+ ++ L ++E + I ++T Sbjct: 826 QEKKQLDEQIDIPLEKSDQELLKTPQLDEPLSQQTESTIVASLEQEIEKCKNLIAEQTGL 885 Query: 1421 -HEYTITLTQRNDEFENVRQQLVEYE---KRIEDLTYEKESELAILRLKMHENANHYETM 1476 E I L + E E QQ+V+ E K++E L E + + + N E Sbjct: 886 IEEMKIKLVNKEKELEEKSQQIVDCERSGKKVETLENELREMFSTIE-EWRYKCNEMEEK 944 Query: 1477 QKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTL 1536 ++ E V +L +I+ ++ L + +EE+ + T L+N+ I I +L Sbjct: 945 MEKLEDTTVTFESKLERQISIISEKENEIIRLKETIEEKDQELQAKYTELQNKMITIDSL 1004 Query: 1537 NDEITNLQNMVRASSSKI 1554 DE N + +++ + I Sbjct: 1005 QDEFNNCKMLIQEKDTSI 1022 Score = 88.2 bits (209), Expect = 2e-15 Identities = 185/1025 (18%), Positives = 413/1025 (40%), Gaps = 90/1025 (8%) Query: 606 ENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQL--QSDQVCSEIKSVH 663 +++A A++ + D + + + K ++ KLA+ + Q ++ SE K Sbjct: 55 KDIARISETALTDTPEENIDDISQAKTAKAKSTLLQKKLAENRKAFEQRNKEISETKRA- 113 Query: 664 LEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNY-----IQENM 718 +EE+++A+ +E + + + K+Q+ T DIM+ +Q +QEN+ Sbjct: 114 VEEKVEAIRQQLEEKDVTV--MAFQKDQISITAVKPVMITSDIMSPIQIETTIMDLQENL 171 Query: 719 DLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESEL-SKYKSR 777 D + + + ++ + A ++ ++ + T +++ + +E+ L +K ++ Sbjct: 172 KEKDSVIESKTKAVTLMSADLSKRGKTTLDTLEDTKDEMRTMQEHFVLLETSLKNKNENL 231 Query: 778 ICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVV 837 + +L+E +D+ LE D+ + E++ SE T D + + L++ + Sbjct: 232 LMQLQER----DDKIVELEDSVDRFRKQINEQK--LSE-TASVDFSRSTMDTLVETKEAM 284 Query: 838 EKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQ 897 + L+ KN LLE+ ++ ++ L++ + L + + Sbjct: 285 KSMQENFVLMESSLKAKNDNLLEQLKDYELKLAEANERVFKL-----ESGIGIVRDPTVD 339 Query: 898 TQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIE-Y 956 + +L+ + I+ IV+K I IE +E + K L E+ + ++ Sbjct: 340 EFVAELQDKIVNISMHGNGAIVEKDNRI----IELENLVEELKQSNKFLEEESKAELQKQ 395 Query: 957 VTQLEAQLQEYKNNIENLNMNV----EELNKMNLELIDKHVQKQQTQSPDYTEQYINEIN 1012 V L + +EY N I +L V EE N++ +L ++ + K+ + D + + N Sbjct: 396 VADLTLKNEEYSNKITDLENFVHKLEEEKNEITAKLPEEGIIKEDEKISDTNAELVRLGN 455 Query: 1013 KLNALLKQKDEEIIALNQ--KINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQ 1070 ++ L ++K ++L ++ + + V D ESK++ T ++E E + + Q Sbjct: 456 QVALLEEEKGNLQLSLVDFDELKASAGDWQERVVDLESKVSAQTKEIEMQIEAIATLENQ 515 Query: 1071 LLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDX 1130 LD Q + + + + E + ++T E+ + E + I M +++ Sbjct: 516 KLDLLQELHMAKQEISSLEAENAESENLRVTAEIKVVDLEEQL--EAIHRMQNESKLESS 573 Query: 1131 XXXXXXXXXXXLKV--QEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLET--LNTELT 1186 ++ QE E S +E+ +T E + I +L+ L E Sbjct: 574 SEVNSAELIKQVETLTQENTELYNRISKFEEKGTS-DTGSTESFEAIQELDKTDLVEEKG 632 Query: 1187 GHDVVNQEQI------NQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIA---E 1237 D + E N+ +K+E L EN L+ + +L + + ++ + Sbjct: 633 SSDTGSTESFERIPENNESMTKIELLTQENSELVIKLTKLEEQLEYIESKSDIDLKLKID 692 Query: 1238 LWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQN 1297 + H T+ + E+K + + + +T + ME+ LQ Sbjct: 693 TLELHKEIEMLSINNTDLTIEPHKLEIETKQSEESEISKRDVDFKTQVNILMEEKDLLQK 752 Query: 1298 KLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQ 1357 ++++ L EK D+ QI LR++IE+ +L+T NQ Sbjct: 753 EVKELRNSLEQWHEKNQDL--QINDLRTKIEE--------LLRENEEVVTKMSELKTSNQ 802 Query: 1358 SYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLE--LTHQLELKDSE 1415 E++ L + E+ +L + N E K L+ + LE D E Sbjct: 803 KL----EENTLKLTEKLDKLNLE-------------KQNIQEKKQLDEQIDIPLEKSDQE 845 Query: 1416 IYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYET 1475 + KT + L+Q+ + + L + ++ ++L E+ + +++K+ N + Sbjct: 846 LL-KTPQLDEPLSQQTES--TIVASLEQEIEKCKNLIAEQTGLIEEMKIKL---VNKEKE 899 Query: 1476 MQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVT 1535 ++++S+ ++ E K+ +L ++ E+ +EE K NEM+ +E E VT Sbjct: 900 LEEKSQ--QIVDCERSGKKVE---TLENELREMFSTIEEWRYKCNEMEEKMEKLEDTTVT 954 Query: 1536 LNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDLAMYM 1595 ++ +++ ++I + + Q + NK + + E + + Sbjct: 955 FESKLERQISIISEKENEIIRLKETIEEKDQELQAKYTELQNKMITIDSLQDEFNNCKML 1014 Query: 1596 LHQRD 1600 + ++D Sbjct: 1015 IQEKD 1019 Score = 79.4 bits (187), Expect = 8e-13 Identities = 188/1000 (18%), Positives = 413/1000 (41%), Gaps = 80/1000 (8%) Query: 147 LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXX 206 L + ++E+ LS L+ K E + + + +N K ++A + Sbjct: 2272 LQHFLEEQKIKLSALESKRSAEEDESIQIVDDLNGKISELQA---VLSKSREEYDLLRKQ 2328 Query: 207 XXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFE 266 D Q+T M++N ++ E + +L ++E D+R + LEA+ Sbjct: 2329 YEQSLMDANDQVTAMRQNADYLKEEAFERTAKL--EMEIVDLR--------QQLEASELN 2378 Query: 267 ISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQ--SIEPSCEEKTEIEEKGSLEIANMTEL 324 ++ L L + KQ S+ S E T++ E+A++ + Sbjct: 2379 VTELRKGLEDALREKSSVEERLTDLTASTEKQVSSLNASMLEVTDLLNTRIQEVADLRQE 2438 Query: 325 TKKIELLEH------LNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNT 378 +K + +EH L ++++N+EL+ K M ++ + K+ + R+S Sbjct: 2439 LQK-QYVEHEEAKTRLQSTVKESNRELDEKRQEMEDLRRSFAEREKE---FVERQSVETV 2494 Query: 379 ASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXX 438 ++ + SQ + E + + + EI + + +++LN+ L E +E Sbjct: 2495 SALV----SQATQELMQR------HAIEIEERDKHVRNLNERLSALEATANE---CLLEK 2541 Query: 439 XXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNE-IAKVQEQLKQ-ELNDEIKDV 496 D I +L+L + ME S + V E A +++QL Q EL ++ Sbjct: 2542 RNNVVQLDARIQELELLRRDLMEKESSL------ASVREGFASMEKQLAQRELELSEREE 2595 Query: 497 NVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKE 556 ++ L + + E + +L ++ + V + + L+++ +++ ++N + D + Sbjct: 2596 TIRKLSLENQRCVETVEELRKRLNESATISANV-NEYTLRVQTLEREVENMRSLLDEKEA 2654 Query: 557 IVRLT-EELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKA 615 I+R EE + + + E L++ + + +++++ +K E N + L+A Sbjct: 2655 ILRKNVEEATEYREIIEKSRIELSELRMEVQKVED---LKNELLEKE-ERVNSLNSELEA 2710 Query: 616 I-SLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEE-QIDALSA 673 LE + +L +++ +L + ++ +I +L S Q + ++ + + Sbjct: 2711 TRKALEETRQNLNEKMSLLDHSNRLLNERQMEIDRLSSLQQDRRSSANMIDGLPVFRMGN 2770 Query: 674 SKKELALVIENLKLDKEQ--LYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEK 731 ++ L I+N+++ + LY +LE+ I + + ++ L ++E S E Sbjct: 2771 GEQNLQHTIDNMQMQQRIHCLYNEKAELESSLLVINARAEEKEKQIHALEQRIETQSQEF 2830 Query: 732 ISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAV---M 788 +S+ +++ ++ IQ Q I ++Q +LY + E E+++ K + E ++V M Sbjct: 2831 VSK--EELHSRDRRSIQEQEQI-VRLQN-ELYAK--EQEINELKYIVAEKESQLSVQASM 2884 Query: 789 EDR--RYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEH 846 E + + L +L + L K++ + EL ++ L + +R E+ ++ Sbjct: 2885 EPQSDEFELREMVQRLTAELYGKEEEVKHTKLTIVELQREVSRLQEFERFSEQTREAVQK 2944 Query: 847 ENKELQKKNQILLEENQNLQISLSDMQQHYNALVEK-ANRTDLAESESTKYQTQLRDLES 905 N E K QI LE + L+ L + + + + A E + + L+S Sbjct: 2945 LNAE---KEQIRLEGEEFLERRLKEKEMEIDEIKRNLAMENQKILDELSFNNRDIESLKS 3001 Query: 906 NLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQ 965 L ++ Q + ++ EDL + N+ + A + +++ K+ E + L+ Q+ Sbjct: 3002 QLTELSTTEQRTKDELRRREEDL-LRVNSDL--AEKKRRLAELSITKDAE-LHNLKIQIS 3057 Query: 966 EYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYT--EQYINEINKLNALLKQKDE 1023 E IE L EE K EL + ++ + T E + E + +LK KD Sbjct: 3058 EKDARIEELVSLYEEGEKRFTELKNTLSAREIEINSLKTLLEDKVKEYQLIQNVLK-KDV 3116 Query: 1024 EIIALNQKINN--AQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEEL 1081 ++ + N + S + +L L + + ++ +L+ + + L Sbjct: 3117 SVLDTSTSTTNPNTETSDDKSKTSTSQELDLALYMLHQRDVRCEELTHELMQLLEERDTL 3176 Query: 1082 QILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPM 1121 Q+ + ++L++ LT PK E T+EP+ Sbjct: 3177 QLRLSNAIRVNEDLRKGTLTNVDLSPKMEPSTSGGTVEPI 3216 >UniRef50_A0BMM9 Cluster: Chromosome undetermined scaffold_117, whole genome shotgun sequence; n=1; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_117, whole genome shotgun sequence - Paramecium tetraurelia Length = 2732 Score = 192 bits (467), Expect = 9e-47 Identities = 282/1393 (20%), Positives = 596/1393 (42%), Gaps = 132/1393 (9%) Query: 216 QQMTKMQENFIAMEAEWKDEKQRLLKDI--ESKDVRISSLEEANKLLEAARFEISLEHSK 273 Q++ +QEN + M + K + ++ +++ E+K+ E + E + ++ L+ S+ Sbjct: 100 QKIQDLQENLVIMSDQMKFRESKIREEVQQETKETSEFGNERVKLITELRKCQVDLQESQ 159 Query: 274 L--AQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELL 331 A + Q L+K I+ ++ E+EEK + +L +KIE L Sbjct: 160 KQNANKFSQIQQLTNKATQIQN-LSKLEIDKLKQQNQELEEKLLQSQQKVDQLAQKIEEL 218 Query: 332 EHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWS---Q 388 + LN Q+ ++E+E+ + E + + + +R+ + ++K + Q Sbjct: 219 KELNSQLNLQSQEVEDVKQKLEKEFQQ-RYDEVEFEIINNRQIIEDLQIQLKELKALNLQ 277 Query: 389 LSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTL 448 L S +N D K + + +Q+ N++L K + K + Sbjct: 278 LESAAINGTFDMKQQISLLQDQTNELQNQNQELQQK---LHAKQIEFDQMNKAKSREIEK 334 Query: 449 IAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSA 508 + Q ++E QQ +E T+ ++E Q Q + E N + + + ++D K + + Sbjct: 335 LKQDKIELQQELE---------QTKQISE----QTQAETESNYKNQMLILQD---KFQKS 378 Query: 509 EEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLS 568 EEQ ++LN +I + ++I+ + +K Q+ N I + +EL S Sbjct: 379 EEQTSKLNQKIQELSADLIQERMLYKNNESQL-------------NGVITQQKDELSQKS 425 Query: 569 QKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRL-KAISLLESQKFDLV 627 V +L E+ LQ H + ++ D YK +++ N T+L + I L+ Q+ Sbjct: 426 SLVLQLTEKIRILQDHSMQQETNISKNIDDYKVLLDQNNQQITQLSEQIKSLKKQQRQQE 485 Query: 628 QE-LHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLK 686 QE ++ Q +++ LA+I+Q + + E + S+ +L+ +IE K Sbjct: 486 QENKQVISQYEQQIKQYLAEITQTK----------IQKNESDNQRQNSESQLSQIIEKQK 535 Query: 687 LDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSK 746 + +Q I+DL N E +Q+ ++ M + + + EK S+ IN E Sbjct: 536 VQLQQANAIIQDLNNQIEQFQQNIQDQEEQRMSVISVKQSLLIEKESQ----INMLESQV 591 Query: 747 IQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLG--- 803 I+ Q + K + + + E + S + I E++ + + L+ K L Sbjct: 592 IKYQNELTQKQDQIIILQQQYEKQKSDFNLAISEKEKNAKLTNQQHQELQNKVSDLTFEV 651 Query: 804 ---SYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLE 860 L +K + E IQ+ N+ L D + E++ KE K Q+ L+ Sbjct: 652 NQLRSLVDKAEVDKESNIQQYNEANQ--QLKDQLNTQNSLIQELQEYLKESNSKEQLALQ 709 Query: 861 ENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQ 920 ++ + ++ +Q L + DL++ E + QT L + LK +++TL Sbjct: 710 KSTQQSLEINQLQLEIGKL-----KNDLSQQEQKQSQTNLEN-SYKLKEQQTQNETLKND 763 Query: 921 KK--KEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNV 978 K + ++D + N Q+ I D ++ ++ ++N++ TQ+ + K ++ LN + Sbjct: 764 FKQIQLVQDKLKQENFQLNEQINDLQIKLQESQENLKQTTQIN---ENQKEQLQKLNDQL 820 Query: 979 -EELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKL-NALLKQKDEEIIALNQKINNAQ 1036 +E K ++ +K +Q Q ++E NKL ++ + KD++I AL ++ +AQ Sbjct: 821 YQEQQKESVNQTEKFYLQQLIQQHKDQVNEVHEKNKLITSISESKDKQIEALKKQGEDAQ 880 Query: 1037 VSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQ--LLDSKQHNEELQILVREQDDQIKE 1094 Y Q T+ E M + Q+ +Q +LD +E + L+ E ++I Sbjct: 881 KHYEQ----------QKQTQYEEMVQLKQKYEQQFHILD-----DEKKSLIAEYTNRIAN 925 Query: 1095 LKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQER 1154 L+E ++ N + E ++ +D ++Q + E Q++ Sbjct: 926 LEEINNDYQKNSSIEQSQF---NQEKLNLKQQLLDQQVKIEKQLKEIEQMQGQLE--QKQ 980 Query: 1155 SVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLL 1214 + + + K E+ + +++QL+ LNT+ + +N+ + + Q+N ++D Sbjct: 981 QEIIQINLKNECEVLQLSEELVQLKQLNTKQV--EEINERDL-MITLHQTQINLQDDQFR 1037 Query: 1215 STVAELRSSISSAVDQRGFEIAELWKQH---LAQREADFQKTEHELR---VQLSAFESKY 1268 ++ L I + + + +I ++ H L Q++ + Q E++++ QL ++++ Sbjct: 1038 LEISNLNVKIDNILKENQIQIEDIHSNHQKQLLQKQNEIQDKEYQIKKLDQQLFDYQAQM 1097 Query: 1269 EQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILR--SE 1326 EQ L+ +Q ++E K+ V L+N Q KE+ + L+ ++ ++E + S+ Sbjct: 1098 EQRLEYIQQK-EQEVEKLSQHNDV--LENDAQQKEQEIIQLKNHSQNLSVELEKFKQYSQ 1154 Query: 1327 IEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXX 1386 +E EK +L+ Q +KQ + ++ ++ L++ Sbjct: 1155 LEQEK---------QQQVILELTENLKQSEQLFKQQNK----SMEDQIKSLEQQITNQNQ 1201 Query: 1387 XXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEK 1446 +N K EL ++ +LK++E ++ E +N+ ++ Q VE Sbjct: 1202 KIVQLQDSINQLNQKYQELKNEKQLKEAEYEKQLQELQNQSDIQNEAIDSQIQTNVEQSD 1261 Query: 1447 RIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVA 1506 +I L K L L+ + E E K++ IE +K +++ +I E N+ + Sbjct: 1262 QISKLEQNKSQLLEELQ-NVVEEKKQVELTYKQA-IEDLKTVQD--QRIAEINKKNQDLV 1317 Query: 1507 EL-NKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTK 1565 +L N L ++ + E++ L+ + + + + +LQ R +K +++ + Sbjct: 1318 QLKNMILIQKDEELEELRQQLQQSQEDFIKQQNLNDSLQIHSRELKNKFDEYIETKFSEE 1377 Query: 1566 QGRDEQLDNTMNK 1578 + + +LD T K Sbjct: 1378 KRLNNELDLTEQK 1390 Score = 173 bits (422), Expect = 3e-41 Identities = 285/1491 (19%), Positives = 645/1491 (43%), Gaps = 113/1491 (7%) Query: 146 HLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXX 205 H N E + Q++ + + IL+L E + + +Q+ + +NK+ Sbjct: 1138 HSQNLSVELEKFKQYSQLEQEKQQQVILELTENLKQSEQLFKQQNKSMEDQIKSLEQQIT 1197 Query: 206 XXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARF 265 + + ++ + + E K+EKQ + E + + + + ++ Sbjct: 1198 NQNQKIVQLQDSINQLNQKY----QELKNEKQLKEAEYEKQLQELQNQSDIQNEAIDSQI 1253 Query: 266 EISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELT 325 + ++E S +LEQ KQ +E + K IE+ +++ + E+ Sbjct: 1254 QTNVEQSDQISKLEQNKSQLLEELQNVVEEKKQ-VELTY--KQAIEDLKTVQDQRIAEIN 1310 Query: 326 KKIELLEHL-NCQIRQTNKELEN-KLATMGTESKAVSSPSKKGSPLISRKSGRNTASK-M 382 KK + L L N + Q ++ELE + ++ + + S I + +N + + Sbjct: 1311 KKNQDLVQLKNMILIQKDEELEELRQQLQQSQEDFIKQQNLNDSLQIHSRELKNKFDEYI 1370 Query: 383 KSPWSQLSSETLNQD---TDKKINK--NEIAKLEMVIQSLNKDLV--DKEYVI--SEKDT 433 ++ +S+ + LN + T++KIN+ ++ + IQ+L D+ D EY+ S+ T Sbjct: 1371 ETKFSE--EKRLNNELDLTEQKINELQEQVDQHAETIQNLQGDIQRKDLEYLQLQSQLQT 1428 Query: 434 XXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVN-EIAKVQEQLKQELNDE 492 + + QL+HQ + D+N +I + +E++++ N Sbjct: 1429 KIQQHTLELSDLGGKMNEEQLKHQIEINQKQ-----QEISDLNFQIQEGKEKIEELSNII 1483 Query: 493 I-KDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVS 551 I K+ +K L E ++ Q+ Q + +I K++ + ++ K KQ++++ + Sbjct: 1484 IDKETMIKSLEETIEGNTNQVQQQSIKIQEHQKSIEGLTLENQNKQKQLEQSA---KIIK 1540 Query: 552 DSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAET 611 D+ E+ LT +L +K ++E LQ + +E ++Y ++ L ET Sbjct: 1541 DTQIELEELTTQLTDQIEKFNQIEGSYLKLQ------QQNKSLE-ELYNNTLK---LLET 1590 Query: 612 RLKAISLLESQKFDLVQELHI-LQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEE-QID 669 + + ++ QK + + +H+ L++ E E + + +Q+ ++ + ++ +ID Sbjct: 1591 KEEDLTTTVIQKNEEIASIHLSLEKLKQESEKEYKQLEDYSYEQLLKKMDDIAQKDWEID 1650 Query: 670 ALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSA 729 L+ ++L + L+ E + K+ +N ++I Q++ ++ + E + Sbjct: 1651 QLNQVVQDLN---QKLQAGMECVEQYDKEFDNQIKEIDELKSKIKQKDKEIKECNEIIEK 1707 Query: 730 EKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVME 789 +K+ E+ ++ TQ + DL ++ + L+K +++I L+ IA + Sbjct: 1708 QKLEIEAVNKQMNEELQLVTQ-SLQENQSNYDLELQAKLAILNKKEAQILNLDFQIAEFQ 1766 Query: 790 DRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENK 849 +L ++ DQ+ +QE+ + EDE + +++ L E E Sbjct: 1767 Q---NLNQQKDQIEELVQERNVLIERQKLIEDEKNQSDKEFKQQIQSLKESLSEFEENYN 1823 Query: 850 ELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRT--DLA---ESESTKYQTQLRDLE 904 L+++++ + + + + +D+QQ Y E + + DL + ++ ++Q +++ + Sbjct: 1824 YLKQQHEEVQNQFASQKELYNDLQQKYEEDQESSQQLIQDLQSQKDKQNIEFQKYIKESD 1883 Query: 905 SNLKRITH----------EHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNI 954 N+++ + + Q LI + +ED + + Q + + LN+ + Sbjct: 1884 LNIQKANNKINQKEEKIAQQQHLIETLQSNLEDKNQQHDEQGQRLFEKQNELNQVILEKQ 1943 Query: 955 EYVTQLEAQLQEYKNNIENLNMNVEELNKM-NLELIDK-HVQKQQTQSPDYTEQYINE-- 1010 +L Q+QE N I + N+ V +L+++ L+ +K + KQ Q+ D +Q + + Sbjct: 1944 TNEKKLSQQIQECNNKIASYNLEVAQLSQLITLKESEKSQLSKQFEQTSDQLKQQLFQQT 2003 Query: 1011 --INKLNALLKQKDEEIIALNQKIN--NAQVSYMSM-VSDYESKLAQFTTKLENMEEEMQ 1065 I +L + + E QKIN N Q+S + +S+ ++ + ++ +EE Sbjct: 2004 QFIQELQDYINESQENESKAGQKINTLNLQISTLEFEISNLNCEILKLQNTIKQSKEEKL 2063 Query: 1066 RVSKQ-LLDSKQHNEELQILVREQDDQIKELKETKLTF---EMNI-PKTEGMIISSTIEP 1120 R+ + D Q ++LQ + E ++ ++ E N+ K E + I Sbjct: 2064 RLEEDHQQDIIQIQQQLQAAISANQLLKNEAQKKQINLFENEQNLNSKIEQQVYEIKILK 2123 Query: 1121 MSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQ--- 1177 ++ E + ++++ + + SA E+++ + +Q Sbjct: 2124 EEIQRLQLEMQRQVKESDSNLNNKNEMIDLLKKQLIDIQNSAANAEEMKDLIQRQLQDQS 2183 Query: 1178 ---LETLNTELTGHD--VVN-QEQINQL---KSKLEQLNTENDNLLSTVAELRSSISSAV 1228 + LN ++ D + N ++QI QL K + EQL TE ++L+ ++ + + Sbjct: 2184 QSQAQQLNQQIKTRDDQITNLKQQIQQLSQSKQQQEQLLTEQISVLNQQIRSKNESMNQL 2243 Query: 1229 DQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFES-KYEQLLDSVQSSTQEETNKIV 1287 D E + +K + Q + + E++ S +S K +Q + + +E NKI Sbjct: 2244 D----ESIKYFKSQIDQSNLTITQLQQEIQSLNSKLQSSKNDQ--NQINEENKELQNKIE 2297 Query: 1288 TMEQVTSL-QNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVA-FXXXXXXXXXXX 1345 ++Q+++ Q++L+ ++ + L+E+ QI+ L S+I D+ Sbjct: 2298 IVQQISNTAQSELEKLKQQILKLEEEKQRQSEQIKQLSSQINDQNSQNLQITQKLLSQKE 2357 Query: 1346 XXXXXDLRTEN--QSYKQMQEQS---ILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEA 1400 DL+ +N + Y+Q +EQS I + +QL+++ + +++E Sbjct: 2358 EKELIDLQQKNIQEQYQQHREQSEKQIYQLTNNVSQLEQTLSEIQNNLLLVNKQKSESEE 2417 Query: 1401 KVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELA 1460 K+ +L QL+ +S++ +Y Q+ + N+ Q+ E ++ + + E+ S+L Sbjct: 2418 KLNKLGQQLQNVNSQLSDSRDKYESENQQQLQQINNLSQENSELQQTLNE-KLEELSKLQ 2476 Query: 1461 ILRLKMHENANHYETMQKESEIERVKLIEELNVKITES--VSLNKQVAELNKALEEEVAK 1518 + K+ +N + + ES+++ + ++E N K E + L Q EL + E + Sbjct: 2477 LDNTKLVQNQKKVDKL--ESQVQELSALKEQNGKQIEQQELRLKSQQQELEQLRENYNLQ 2534 Query: 1519 TNEMQTA---LENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQ 1566 N++ + + EI+ L+ EI LQ+ + S++QK+ + + +Q Sbjct: 2535 KNQLNSLNQQIAQYEIDKDKLSKEIKQLQSQNQNYLSQVQKYQDYINQQQQ 2585 Score = 165 bits (400), Expect = 1e-38 Identities = 300/1452 (20%), Positives = 625/1452 (43%), Gaps = 161/1452 (11%) Query: 158 LSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQ 217 +S+LQ + ++ +LQ+K++ K + NKA + ++ Sbjct: 293 ISLLQDQTNELQNQNQELQQKLHAKQIEFDQMNKAKS---------------------RE 331 Query: 218 MTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH-SKLAQ 276 + K++++ I ++ E + KQ E S + L+ +F+ S E SKL Q Sbjct: 332 IEKLKQDKIELQQELEQTKQ----ISEQTQAETESNYKNQMLILQDKFQKSEEQTSKLNQ 387 Query: 277 ELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELL-EHLN 335 ++++ Q ++K E+ +K SL + +LT+KI +L +H Sbjct: 388 KIQELSADLIQERMLYKNNESQLNGVITQQKDELSQKSSL----VLQLTEKIRILQDHSM 443 Query: 336 CQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASK-MKSPWSQLSSETL 394 Q +K +++ + ++ ++ S++ L ++ + +K + S + Q + L Sbjct: 444 QQETNISKNIDDYKVLLDQNNQQITQLSEQIKSLKKQQRQQEQENKQVISQYEQQIKQYL 503 Query: 395 NQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQL 454 + T KI KNE +S +++K+ V ++ + +I L Sbjct: 504 AEITQTKIQKNESDNQRQNSESQLSQIIEKQKVQLQQ-------------ANAIIQDLNN 550 Query: 455 EHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQ 514 + +Q + N +D E +KQ L E K+ + L ++ + ++TQ Sbjct: 551 QIEQFQQ---------NIQDQEEQRMSVISVKQSLLIE-KESQINMLESQVIKYQNELTQ 600 Query: 515 LNDEIDAANKNMIKVKSNHKLKLKQMQKT--IDNFSKVSDSNKEIVRLTEELHHLSQKVA 572 D+I + K KS+ L + + +K + N NK + LT E++ L V Sbjct: 601 KQDQIIILQQQYEKQKSDFNLAISEKEKNAKLTNQQHQELQNK-VSDLTFEVNQLRSLVD 659 Query: 573 ELEEEK-GNLQLHLVDYDSGRMIESDVYKKMIE--MENLAETRLK-AISLLESQKFDLVQ 628 + E +K N+Q + + + + + +I+ E L E+ K ++L +S + L Sbjct: 660 KAEVDKESNIQQY-NEANQQLKDQLNTQNSLIQELQEYLKESNSKEQLALQKSTQQSL-- 716 Query: 629 ELHILQQKYDEVEDKLADISQLQSD-QVCSEIKSVHLEEQIDALSASKKELALVIENLKL 687 E++ LQ + ++++ L+ Q QS + + K + Q + L K++ LV + LK Sbjct: 717 EINQLQLEIGKLKNDLSQQEQKQSQTNLENSYKLKEQQTQNETLKNDFKQIQLVQDKLKQ 776 Query: 688 DKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKI 747 + QL I DL+ ++ L+ Q N + ++L+K++ + E +++S Sbjct: 777 ENFQLNEQINDLQIKLQESQENLKQTTQINENQKEQLQKLNDQLYQE------QQKESVN 830 Query: 748 QTQ-FGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERK--ADQLGS 804 QT+ F + IQ+ + + + +L SI+ +D++ +K D Sbjct: 831 QTEKFYLQQLIQQHKDQVNEVHEK--------NKLITSISESKDKQIEALKKQGEDAQKH 882 Query: 805 YLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQN 864 Y Q+KQ Y E + + + +L D EK+ L E+ N+ L E N + Sbjct: 883 YEQQKQTQYEEMVQLKQKYEQQFHILDD-----EKKSLIAEYTNRIAN-----LEEINND 932 Query: 865 LQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLI-VQKKK 923 Q + S Q +N EK N + K + QL+++E ++ + Q +I + K Sbjct: 933 YQKNSSIEQSQFNQ--EKLNLKQQLLDQQVKIEKQLKEIEQMQGQLEQKQQEIIQINLKN 990 Query: 924 EIEDLEIEFNTQIESAIRDKKV--LNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEEL 981 E E L++ + K+V +NE+ + TQ+ Q +++ I NLN+ ++ + Sbjct: 991 ECEVLQLSEELVQLKQLNTKQVEEINERDLMITLHQTQINLQDDQFRLEISNLNVKIDNI 1050 Query: 982 ---NKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVS 1038 N++ +E I + QKQ Q NEI +K+ D+++ ++ ++ Sbjct: 1051 LKENQIQIEDIHSNHQKQLLQKQ-------NEIQDKEYQIKKLDQQLFDYQAQMEQ-RLE 1102 Query: 1039 YMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVR--EQDDQIKELK 1096 Y+ KL+Q LEN + Q+ ++++ K H++ L + + +Q Q+++ K Sbjct: 1103 YIQQKEQEVEKLSQHNDVLEN---DAQQKEQEIIQLKNHSQNLSVELEKFKQYSQLEQEK 1159 Query: 1097 ETKLTFEM--NIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLK---VQEEEEFI 1151 + ++ E+ N+ ++E + + M D +++ L+ Q +++ Sbjct: 1160 QQQVILELTENLKQSE-QLFKQQNKSMEDQIKSLEQQITNQNQKIVQLQDSINQLNQKYQ 1218 Query: 1152 QERSVLQEQSAKLNTELQECYTKI-IQLETLNTELTGHDVVNQEQINQLKSKLEQLNTEN 1210 + ++ Q + A+ +LQE + IQ E +++++ +V +QI++L+ QL E Sbjct: 1219 ELKNEKQLKEAEYEKQLQELQNQSDIQNEAIDSQIQ-TNVEQSDQISKLEQNKSQLLEEL 1277 Query: 1211 DNLLSTVAELRSSISSAVDQ----RGFEIAELWK--QHLAQRE--ADFQKTE--HELRVQ 1260 N++ ++ + A++ + IAE+ K Q L Q + QK E ELR Q Sbjct: 1278 QNVVEEKKQVELTYKQAIEDLKTVQDQRIAEINKKNQDLVQLKNMILIQKDEELEELRQQ 1337 Query: 1261 LSAFES---KYEQLLDSVQSSTQEETNKI-----VTMEQVTSLQNKLQDKEEHLRNLQEK 1312 L + K + L DS+Q ++E NK + L N+L E+ + LQE+ Sbjct: 1338 LQQSQEDFIKQQNLNDSLQIHSRELKNKFDEYIETKFSEEKRLNNELDLTEQKINELQEQ 1397 Query: 1313 YADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINE 1372 I+ L+ +I+ + + + +L + Q + + IN+ Sbjct: 1398 VDQHAETIQNLQGDIQRKDLEYLQLQSQLQTKIQQHTLELSDLGGKMNEEQLKHQIEINQ 1457 Query: 1373 ENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRND 1432 + ++ + ++ + + K+ EL++ + D E K+ E TI Sbjct: 1458 KQQEISDLN-----------FQIQEGKEKIEELSN--IIIDKETMIKSLEETIEGNTNQV 1504 Query: 1433 EFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELN 1492 + ++++ Q E++K IE LT E +++ + ++ ++A + Q E E +L +++ Sbjct: 1505 QQQSIKIQ--EHQKSIEGLTLENQNK----QKQLEQSAKIIKDTQIELEELTTQLTDQIE 1558 Query: 1493 VKITESVSLNKQVAELNKALEEEVAKTNE-MQTALENQEIEIVTLNDEITNLQNMVRASS 1551 K + ++ + NK+LEE T + ++T E+ ++ N+EI ++ + Sbjct: 1559 -KFNQIEGSYLKLQQQNKSLEELYNNTLKLLETKEEDLTTTVIQKNEEIASIHLSLEKLK 1617 Query: 1552 SKIQKHVSFASD 1563 + +K D Sbjct: 1618 QESEKEYKQLED 1629 Score = 163 bits (396), Expect = 4e-38 Identities = 295/1582 (18%), Positives = 683/1582 (43%), Gaps = 124/1582 (7%) Query: 91 SESLANTLKQKEILMEKIKQYK-ELSKRSSTTIVRXXXXXXXXXXXXXXX--QLGDVTHL 147 +E+L N KQ +++ +K+KQ +L+++ + ++ Q + L Sbjct: 757 NETLKNDFKQIQLVQDKLKQENFQLNEQINDLQIKLQESQENLKQTTQINENQKEQLQKL 816 Query: 148 SNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXX 207 ++ + ++ SV Q + ++ I ++++NE + KNK T Sbjct: 817 NDQLYQEQQKESVNQTEKFYLQQLIQQHKDQVNE----VHEKNKLITSISESKDKQIEAL 872 Query: 208 XXXXEDTKQ--QMTKMQENFIAMEAEWKDEKQRLLKDIESKDV------RISSLEEAN-- 257 ED ++ + K + ++ + K E+Q + D E K + RI++LEE N Sbjct: 873 KKQGEDAQKHYEQQKQTQYEEMVQLKQKYEQQFHILDDEKKSLIAEYTNRIANLEEINND 932 Query: 258 --KLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGS 315 K + + + E L Q+L + Q +E +E +I K Sbjct: 933 YQKNSSIEQSQFNQEKLNLKQQLLDQQVKIEKQLKEIEQMQGQ-LEQKQQEIIQINLKNE 991 Query: 316 LEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSG 375 E+ ++E EL++ +Q +E+ + + ++ + IS + Sbjct: 992 CEVLQLSE-----ELVQLKQLNTKQV-EEINERDLMITLHQTQINLQDDQFRLEISNLNV 1045 Query: 376 RNTASKMKSPWSQLSSETLNQDTDKKI--NKNEIAKLEMVIQSLNKDLVDKEYVISEKDT 433 + + +K +Q+ E ++ + K++ +NEI E I+ L++ L D + + ++ Sbjct: 1046 K-IDNILKE--NQIQIEDIHSNHQKQLLQKQNEIQDKEYQIKKLDQQLFDYQAQMEQRLE 1102 Query: 434 XXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVN-EIAKVQE--QLKQELN 490 L+ + QQ + +I + ++++++ E+ K ++ QL+QE Sbjct: 1103 YIQQKEQEVEKLSQHNDVLENDAQQKEQ--EIIQLKNHSQNLSVELEKFKQYSQLEQEKQ 1160 Query: 491 DEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKV 550 ++ + +L E LK +E+ Q N ++ K++ + +N K+ Q+Q +I+ ++ Sbjct: 1161 QQV----ILELTENLKQSEQLFKQQNKSMEDQIKSLEQQITNQNQKIVQLQDSINQLNQK 1216 Query: 551 SDSNKEIVRLTE-----ELHHLSQKVAELEEEK--GNLQLHLVDYDSGRMIESDVYKKMI 603 K +L E +L L Q ++++ E +Q ++ D +E + + + Sbjct: 1217 YQELKNEKQLKEAEYEKQLQEL-QNQSDIQNEAIDSQIQTNVEQSDQISKLEQNKSQLLE 1275 Query: 604 EMENLAETRLKAISLLESQKFDLVQELHILQ-QKYDEVEDKLADISQL------QSDQVC 656 E++N+ E + K + L Q +++L +Q Q+ E+ K D+ QL Q D+ Sbjct: 1276 ELQNVVEEK-KQVELTYKQA---IEDLKTVQDQRIAEINKKNQDLVQLKNMILIQKDEEL 1331 Query: 657 SEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQE 716 E++ + Q D + +L I + +L K + I+ ++++ + N+L Q+ Sbjct: 1332 EELRQQLQQSQEDFIKQQNLNDSLQIHSREL-KNKFDEYIETKFSEEKRLNNELDLTEQK 1390 Query: 717 NMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELS---- 772 +L +++++ AE I L I ++ +Q Q + KIQ+ L + ++ +++ Sbjct: 1391 INELQEQVDQ-HAETIQNLQGDIQRKDLEYLQLQSQLQTKIQQHTLELSDLGGKMNEEQL 1449 Query: 773 KYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYS--EYTIQ--EDELVNRLA 828 K++ I + ++ I+ + + + K ++L + + +K+ E TI+ +++ + Sbjct: 1450 KHQIEINQKQQEISDLNFQIQEGKEKIEELSNIIIDKETMIKSLEETIEGNTNQVQQQSI 1509 Query: 829 VLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDL 888 + +H + +E LE +++ K+L++ +I+ ++ QI L ++ +EK N+ + Sbjct: 1510 KIQEHQKSIEGLTLENQNKQKQLEQSAKII----KDTQIELEELTTQLTDQIEKFNQIEG 1565 Query: 889 AESESTKYQTQLRDLESNLKRI--THEHQ--TLIVQKKKEIEDLEIEFNTQIESAIRDKK 944 + + + L +L +N ++ T E T ++QK +EI + + + + ++ K Sbjct: 1566 SYLKLQQQNKSLEELYNNTLKLLETKEEDLTTTVIQKNEEIASIHLSLEKLKQESEKEYK 1625 Query: 945 VLNE-KYE---KNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQS 1000 L + YE K ++ + Q + ++ + +++LN ++ + +E DK Q + Sbjct: 1626 QLEDYSYEQLLKKMDDIAQKDWEIDQLNQVVQDLNQKLQAGMEC-VEQYDKEFDNQIKEI 1684 Query: 1001 PDYT---EQYINEINKLNALLKQKDEEIIALNQKINNA-QVSYMSMV---SDYESKLAQF 1053 + +Q EI + N +++++ EI A+N+++N Q+ S+ S+Y+ +L Sbjct: 1685 DELKSKIKQKDKEIKECNEIIEKQKLEIEAVNKQMNEELQLVTQSLQENQSNYDLELQAK 1744 Query: 1054 TTKLENMEEEMQRVSKQLLDSKQH----NEELQILVREQDDQIKELK-------ETKLTF 1102 L E ++ + Q+ + +Q+ ++++ LV+E++ I+ K ++ F Sbjct: 1745 LAILNKKEAQILNLDFQIAEFQQNLNQQKDQIEELVQERNVLIERQKLIEDEKNQSDKEF 1804 Query: 1103 EMNIPKTEGMI--ISSTIEPMSDDANNVDXXXXXXXXXXXXL--KVQEEEEFIQER-SVL 1157 + I + + + V L K +E++E Q+ L Sbjct: 1805 KQQIQSLKESLSEFEENYNYLKQQHEEVQNQFASQKELYNDLQQKYEEDQESSQQLIQDL 1864 Query: 1158 QEQSAKLNTELQECYTKI-IQLETLNTELTG-HDVVNQEQ--INQLKSKLEQLNTENDNL 1213 Q Q K N E Q+ + + ++ N ++ + + Q+Q I L+S LE N ++D Sbjct: 1865 QSQKDKQNIEFQKYIKESDLNIQKANNKINQKEEKIAQQQHLIETLQSNLEDKNQQHDEQ 1924 Query: 1214 LSTVAELRSSISSAVDQRGFEIAELWKQ--HLAQREADFQKTEHELRVQLSAFESKYEQL 1271 + E ++ ++ + ++ +L +Q + A + +L ++ ES+ QL Sbjct: 1925 GQRLFEKQNELNQVILEKQTNEKKLSQQIQECNNKIASYNLEVAQLSQLITLKESEKSQL 1984 Query: 1272 LDSVQSSTQEETNKIVTMEQ-VTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDE 1330 + ++ + ++ Q + LQ+ + + +E+ +K + QI L EI + Sbjct: 1985 SKQFEQTSDQLKQQLFQQTQFIQELQDYINESQENESKAGQKINTLNLQISTLEFEISNL 2044 Query: 1331 KVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXX 1390 Q Q+Q+Q I+ N LK + Sbjct: 2045 NCEILKLQNTIKQSKEEKLRLEEDHQQDIIQIQQQLQAAISA-NQLLKNEAQKKQINLFE 2103 Query: 1391 XXXRVNDA-EAKVLE---LTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEK 1446 +N E +V E L +++ E+ ++ E L +N+ + +++QL++ + Sbjct: 2104 NEQNLNSKIEQQVYEIKILKEEIQRLQLEMQRQVKESDSNLNNKNEMIDLLKKQLIDIQN 2163 Query: 1447 RIEDLTYEKESELAILRLKMHENAN--HYETMQKESEIERVKL-IEELNV-KITESVSLN 1502 + K+ L+ + A + + ++ +I +K I++L+ K + L Sbjct: 2164 SAANAEEMKDLIQRQLQDQSQSQAQQLNQQIKTRDDQITNLKQQIQQLSQSKQQQEQLLT 2223 Query: 1503 KQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFAS 1562 +Q++ LN+ + + N++ +++ + +I N IT LQ +++ +SK+Q S + Sbjct: 2224 EQISVLNQQIRSKNESMNQLDESIKYFKSQIDQSNLTITQLQQEIQSLNSKLQ---SSKN 2280 Query: 1563 DTKQGRDEQLDNTMNKELLDAV 1584 D Q +E + E++ + Sbjct: 2281 DQNQINEENKELQNKIEIVQQI 2302 Score = 161 bits (392), Expect = 1e-37 Identities = 293/1469 (19%), Positives = 627/1469 (42%), Gaps = 131/1469 (8%) Query: 143 DVTHLSNTIK-EKDNALSVLQVKMKIMETTILDLQEKINEKDQII--EAKNKATTXXXXX 199 D+ L N I +KD L L+ +++ + + Q+ +N+ QI E KNK Sbjct: 1315 DLVQLKNMILIQKDEELEELRQQLQQSQEDFIK-QQNLNDSLQIHSRELKNKFDEYIETK 1373 Query: 200 XXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKL 259 + T+Q++ ++QE + AE Q L DI+ KD+ L+ Sbjct: 1374 FSEEKRLNNEL-DLTEQKINELQEQ-VDQHAE---TIQNLQGDIQRKDLEYLQLQSQ--- 1425 Query: 260 LEAARFEISLEHSKLAQEL-EQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEI 318 L+ + +LE S L ++ E+ ++ + + E K +IEE ++ I Sbjct: 1426 LQTKIQQHTLELSDLGGKMNEEQLKHQIEINQKQQEISDLNFQIQ-EGKEKIEELSNIII 1484 Query: 319 ANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNT 378 T + E +E Q++Q + +++ ++ E + + +K+ S K ++T Sbjct: 1485 DKETMIKSLEETIEGNTNQVQQQSIKIQEHQKSI--EGLTLENQNKQKQLEQSAKIIKDT 1542 Query: 379 ASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDK-EYVISEKDTXXXX 437 +++ +QL+ D +K N+ E + L++ Q NK L + + +T Sbjct: 1543 QIELEELTTQLT------DQIEKFNQIEGSYLKL--QQQNKSLEELYNNTLKLLETKEED 1594 Query: 438 XXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVN 497 K+ IA + L ++ + + ++ K + + Q+ + EI +N Sbjct: 1595 LTTTVIQKNEEIASIHLSLEKLKQESEKEYKQLEDYSYEQLLKKMDDIAQK-DWEIDQLN 1653 Query: 498 --VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNK 555 V+DL +KL++ E + Q + E D N IK K K+KQ K I +++ + K Sbjct: 1654 QVVQDLNQKLQAGMECVEQYDKEFD----NQIKEIDELKSKIKQKDKEIKECNEIIEKQK 1709 Query: 556 -EIVRLTEELHHLSQKVAE-LEEEKGNLQLHLVDYDSGRMIESDVYKKMIEME-NLAETR 612 EI + ++++ Q V + L+E + N L L + I + +++ ++ +AE + Sbjct: 1710 LEIEAVNKQMNEELQLVTQSLQENQSNYDLEL---QAKLAILNKKEAQILNLDFQIAEFQ 1766 Query: 613 LKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSV-HLEEQIDAL 671 + ++ + Q +LVQE ++L ++ +ED+ + Q+ S +S+ EE + L Sbjct: 1767 -QNLNQQKDQIEELVQERNVLIERQKLIEDEKNQSDKEFKQQIQSLKESLSEFEENYNYL 1825 Query: 672 SASKKELALVIENLKLDKEQLYGTIKD-LENDKEDIMNKLQNYIQENMDLTD----KLEK 726 +E ++N +++LY ++ E D+E +Q+ +Q D + K K Sbjct: 1826 KQQHEE----VQNQFASQKELYNDLQQKYEEDQESSQQLIQD-LQSQKDKQNIEFQKYIK 1880 Query: 727 MSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIA 786 S I + KIN +E+ Q Q I+ +Q N+E + ++ + RL E Sbjct: 1881 ESDLNIQKANNKINQKEEKIAQQQHLIET-LQS------NLEDKNQQHDEQGQRLFEKQN 1933 Query: 787 VMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEH 846 + + +L +QE + Y ++ +L ++L L + EK L + Sbjct: 1934 ELNQVILEKQTNEKKLSQQIQECNNKIASYNLEVAQL-SQLITLKES----EKSQLSKQF 1988 Query: 847 ENKELQKKNQILLEEN--QNLQISLSDMQQHYNALVEKANRTDLA----ESESTKYQTQL 900 E Q K Q+ + Q LQ +++ Q++ + +K N +L E E + ++ Sbjct: 1989 EQTSDQLKQQLFQQTQFIQELQDYINESQENESKAGQKINTLNLQISTLEFEISNLNCEI 2048 Query: 901 RDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQL 960 L++ +K+ E L +++I I+ Q+++AI ++L + +K Sbjct: 2049 LKLQNTIKQSKEEKLRLEEDHQQDI----IQIQQQLQAAISANQLLKNEAQKK------- 2097 Query: 961 EAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQ 1020 Q+ ++N +NLN +E+ ++++ + +Q+ Q + ++ + +N N ++ Sbjct: 2098 --QINLFENE-QNLNSKIEQ-QVYEIKILKEEIQRLQLEMQRQVKESDSNLNNKNEMIDL 2153 Query: 1021 KDEEIIALNQKINNAQ----VSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQ 1076 +++I + NA+ + + +S+ Q +++ ++++ + +Q+ Q Sbjct: 2154 LKKQLIDIQNSAANAEEMKDLIQRQLQDQSQSQAQQLNQQIKTRDDQITNLKQQIQQLSQ 2213 Query: 1077 HNEELQILVREQ----DDQIKELKETKLTFEMNIPKTEGMIISS--TIEPMSDDANNVDX 1130 ++ + L+ EQ + QI+ E+ + +I + I S TI + + +++ Sbjct: 2214 SKQQQEQLLTEQISVLNQQIRSKNESMNQLDESIKYFKSQIDQSNLTITQLQQEIQSLNS 2273 Query: 1131 XXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDV 1190 + +E +E + ++Q+ S +EL++ +I++LE Sbjct: 2274 KLQSSKNDQNQIN-EENKELQNKIEIVQQISNTAQSELEKLKQQILKLEEEKQR------ 2326 Query: 1191 VNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREAD- 1249 EQI QL S++ N++N + + + +D + I E ++QH Q E Sbjct: 2327 -QSEQIKQLSSQINDQNSQNLQITQKLLSQKEE-KELIDLQQKNIQEQYQQHREQSEKQI 2384 Query: 1250 FQKTEHELRVQLSAFESKYEQLLDSVQSSTQEET-NKIVTMEQVTSLQNKLQDKEEHLRN 1308 +Q T + +++ + E + LL + Q S EE NK+ +Q+ ++ ++L D + + Sbjct: 2385 YQLTNNVSQLEQTLSEIQNNLLLVNKQKSESEEKLNKLG--QQLQNVNSQLSDSRDKYES 2442 Query: 1309 LQEKYADVINQIEILRSEIED------EKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQM 1362 ++ IN + SE++ E+++ L ++ Q + Sbjct: 2443 ENQQQLQQINNLSQENSELQQTLNEKLEELSKLQLDNTKLVQNQKKVDKLESQVQELSAL 2502 Query: 1363 QEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDS---EIYQK 1419 +EQ+ I ++ +LK + N + ++ KD EI Q Sbjct: 2503 KEQNGKQIEQQELRLKSQQQELEQLRENYNLQKNQLNSLNQQIAQYEIDKDKLSKEIKQL 2562 Query: 1420 THEYTITLTQRNDEFENVRQQLVEYEKR--------IEDLTYEK-ESELAILRLKMHENA 1470 + L+Q + + QQ E EK I D ++ E+EL IL++K+ + Sbjct: 2563 QSQNQNYLSQVQKYQDYINQQQQELEKNTISNRSIVINDAQGQQLEAELKILQVKLVQQL 2622 Query: 1471 NHYETM--QKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALEN 1528 N+Y+ + K+++ + K+ E+L+ + V +++ + + E++ K N +N Sbjct: 2623 NNYKQLIQDKKNQEIKAKINEDLDQIKKDYVMALEKIGIFIRGI-EDLEKVN----GPKN 2677 Query: 1529 QEIEIVTLNDEITNLQNMVRASSSKIQKH 1557 Q+ + I + + + K+ KH Sbjct: 2678 QQYHVFNFQKRIKQINSRTQRFYFKVCKH 2706 Score = 155 bits (376), Expect = 1e-35 Identities = 262/1429 (18%), Positives = 633/1429 (44%), Gaps = 122/1429 (8%) Query: 221 MQENFIAMEAEWKDEKQRLLK---DIESKDVRISSLEEANKLLE-AARFEISLEH-SKLA 275 ++EN I +E + +++LL+ +I+ K+ +I L++ +L + A+ E LE+ + Sbjct: 1051 LKENQIQIEDIHSNHQKQLLQKQNEIQDKEYQIKKLDQ--QLFDYQAQMEQRLEYIQQKE 1108 Query: 276 QELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLN 335 QE+E+ ++ I+ + E + + E K+ +++ L Sbjct: 1109 QEVEKLSQHNDVLENDAQQKEQEIIQLKNHSQNLSVELEKFKQYSQLEQEKQQQVILELT 1168 Query: 336 CQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLN 395 ++Q+ + + + +M + K++ + I + +++ +++ + +L +E Sbjct: 1169 ENLKQSEQLFKQQNKSMEDQIKSLEQQITNQNQKIVQL--QDSINQLNQKYQELKNE--- 1223 Query: 396 QDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLE 455 K++ + E K +Q N+ + E + S+ T + +QL E Sbjct: 1224 ----KQLKEAEYEKQLQELQ--NQSDIQNEAIDSQIQTNVEQSDQISKLEQNK-SQLLEE 1276 Query: 456 HQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKD-VNVKDLIEKLKSAEEQITQ 514 Q +E + + T + + ++ VQ+Q E+N + +D V +K++I L +E++ + Sbjct: 1277 LQNVVEEKKQVEL-TYKQAIEDLKTVQDQRIAEINKKNQDLVQLKNMI--LIQKDEELEE 1333 Query: 515 LNDEIDAANKNMIKVKS-NHKLKL--KQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKV 571 L ++ + ++ IK ++ N L++ ++++ D + + S ++ RL EL QK+ Sbjct: 1334 LRQQLQQSQEDFIKQQNLNDSLQIHSRELKNKFDEYIETKFSEEK--RLNNELDLTEQKI 1391 Query: 572 AELEEE-----------KGNLQLHLVDY-DSGRMIESDVYKKMIEMENLA----ETRLK- 614 EL+E+ +G++Q ++Y +++ + + +E+ +L E +LK Sbjct: 1392 NELQEQVDQHAETIQNLQGDIQRKDLEYLQLQSQLQTKIQQHTLELSDLGGKMNEEQLKH 1451 Query: 615 --AISLLESQKFDLVQELHILQQKYDEVEDKLADI-SQLQSDQVCSEIKSVHLEEQIDAL 671 I+ + + DL ++ ++K +E+ + + D + ++S + E + +++Q + Sbjct: 1452 QIEINQKQQEISDLNFQIQEGKEKIEELSNIIIDKETMIKSLEETIEGNTNQVQQQSIKI 1511 Query: 672 SASKKEL-ALVIENLKLDK--EQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMS 728 +K + L +EN K EQ IKD + + E++ +L + I++ + K+ Sbjct: 1512 QEHQKSIEGLTLENQNKQKQLEQSAKIIKDTQIELEELTTQLTDQIEKFNQIEGSYLKLQ 1571 Query: 729 AEK--ISEL----LAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSK-YKS----- 776 + + EL L + +E+ T + +I L +E ++ E K YK Sbjct: 1572 QQNKSLEELYNNTLKLLETKEEDLTTTVIQKNEEIASIHLSLEKLKQESEKEYKQLEDYS 1631 Query: 777 --RICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYT------IQE-DELVNRL 827 ++ + + IA + L + L LQ + +Y I+E DEL +++ Sbjct: 1632 YEQLLKKMDDIAQKDWEIDQLNQVVQDLNQKLQAGMECVEQYDKEFDNQIKEIDELKSKI 1691 Query: 828 AV----LMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKA 883 + + + ++EKQ LEIE NK++ ++ Q++ + Q Q + Q A++ K Sbjct: 1692 KQKDKEIKECNEIIEKQKLEIEAVNKQMNEELQLVTQSLQENQSNYDLELQAKLAILNKK 1751 Query: 884 NRTDL-AESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRD 942 L + + ++Q L + ++ + E LI +++K IED + + + + + I+ Sbjct: 1752 EAQILNLDFQIAEFQQNLNQQKDQIEELVQERNVLI-ERQKLIEDEKNQSDKEFKQQIQS 1810 Query: 943 KKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPD 1002 K ++E+N Y+ Q ++Q + + L ++++ + + E + +Q Q+Q Sbjct: 1811 LKESLSEFEENYNYLKQQHEEVQNQFASQKELYNDLQQKYEEDQESSQQLIQDLQSQKDK 1870 Query: 1003 YTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEE 1062 ++ I + + +++ + +I +KI Q ++ S+ E K Q + + + E Sbjct: 1871 QNIEFQKYIKESDLNIQKANNKINQKEEKIAQQQHLIETLQSNLEDKNQQHDEQGQRLFE 1930 Query: 1063 EMQRVSKQLLDSKQHNEELQILVREQDDQIK--ELKETKLTFEMNIPKTEGMIISSTIEP 1120 + +++ +L+ + + ++L ++E +++I L+ +L+ + + ++E +S E Sbjct: 1931 KQNELNQVILEKQTNEKKLSQQIQECNNKIASYNLEVAQLSQLITLKESEKSQLSKQFEQ 1990 Query: 1121 MSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLET 1180 SD +QE +++I E QE +K Q+ T +Q+ T Sbjct: 1991 TSDQLKQ--------QLFQQTQFIQELQDYINES---QENESKAG---QKINTLNLQIST 2036 Query: 1181 LNTELTGHDVVNQEQINQLK-SKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELW 1239 L E++ + + N +K SK E+L E D+ + +++ + +A+ +L Sbjct: 2037 LEFEISNLNCEILKLQNTIKQSKEEKLRLEEDH-QQDIIQIQQQLQAAISAN-----QLL 2090 Query: 1240 KQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKL 1299 K +++ + + E L ++ + + L + +Q E ++ + + +N++ Sbjct: 2091 KNEAQKKQINLFENEQNLNSKIEQQVYEIKILKEEIQRLQLEMQRQVKESDSNLNNKNEM 2150 Query: 1300 QD-KEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQS 1358 D ++ L ++Q A+ ++++ +++D+ + +L+ + Q Sbjct: 2151 IDLLKKQLIDIQNSAANAEEMKDLIQRQLQDQSQSQAQQLNQQIKTRDDQITNLKQQIQQ 2210 Query: 1359 Y---KQMQEQ----SILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLEL 1411 KQ QEQ I +N++ +S +++ + + +L +++ Sbjct: 2211 LSQSKQQQEQLLTEQISVLNQQIRSKNESMNQLDESIKYFKSQIDQSNLTITQLQQEIQS 2270 Query: 1412 KDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENAN 1471 +S++ ++ + + N E +N + ++V+ EK + IL+L+ + Sbjct: 2271 LNSKLQSSKNDQN-QINEENKELQN-KIEIVQQISNTAQSELEKLKQ-QILKLEEEKQRQ 2327 Query: 1472 HYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEI 1531 + Q S+I N++IT+ + K+ EL ++ + + + Q E E Sbjct: 2328 SEQIKQLSSQINDQ---NSQNLQITQKLLSQKEEKELIDLQQKNIQE--QYQQHREQSEK 2382 Query: 1532 EIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKEL 1580 +I L + ++ L+ + S+IQ ++ + K +E+L N + ++L Sbjct: 2383 QIYQLTNNVSQLEQTL----SEIQNNLLLVNKQKSESEEKL-NKLGQQL 2426 Score = 113 bits (272), Expect = 4e-23 Identities = 166/884 (18%), Positives = 386/884 (43%), Gaps = 82/884 (9%) Query: 730 EKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVME 789 E+ +++L+K+ E + Q + ++ IEN++ + +K +I L+E++ +M Sbjct: 55 EETNKVLSKLEVVENDEDSNQRSSET-VESLQKVIENLQKDCNKKDQKIQDLQENLVIMS 113 Query: 790 DRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRL----AVLMDHDRVVEKQLLEIE 845 D+ ++ + ++ +Q++ K SE+ + +L+ L L + + + +I+ Sbjct: 114 DQ---MKFRESKIREEVQQETKETSEFGNERVKLITELRKCQVDLQESQKQNANKFSQIQ 170 Query: 846 H-ENKELQKKNQILLE------ENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQT 898 NK Q +N LE +NQ L+ L QQ + L +K S+ Sbjct: 171 QLTNKATQIQNLSKLEIDKLKQQNQELEEKLLQSQQKVDQLAQKIEELKELNSQLNLQSQ 230 Query: 899 QLRD----LESNLKRITHEHQTLIVQKKKEIEDLEIE------FNTQIES-AIRDKKVLN 947 ++ D LE ++ E + I+ ++ IEDL+I+ N Q+ES AI + Sbjct: 231 EVEDVKQKLEKEFQQRYDEVEFEIINNRQIIEDLQIQLKELKALNLQLESAAINGTFDMK 290 Query: 948 EKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDK------HVQKQQTQSP 1001 ++ + +L+ Q QE + + + +++NK I+K +Q++ Q+ Sbjct: 291 QQISLLQDQTNELQNQNQELQQKLHAKQIEFDQMNKAKSREIEKLKQDKIELQQELEQTK 350 Query: 1002 DYTEQ--------YINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQF 1053 +EQ Y N++ L ++ +E+ LNQKI + Y++ +Q Sbjct: 351 QISEQTQAETESNYKNQMLILQDKFQKSEEQTSKLNQKIQELSADLIQERMLYKNNESQL 410 Query: 1054 TTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMI 1113 + ++E+ + S +L Q E+++IL QD +++ ET ++ NI + ++ Sbjct: 411 NGVITQQKDELSQKSSLVL---QLTEKIRIL---QDHSMQQ--ETNIS--KNIDDYKVLL 460 Query: 1114 ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQE-CY 1172 D NN LK Q+ ++ + + V+ + ++ L E Sbjct: 461 ----------DQNN--QQITQLSEQIKSLKKQQRQQEQENKQVISQYEQQIKQYLAEITQ 508 Query: 1173 TKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRG 1232 TKI + E+ N ++Q I + K +L+Q N +L + + + + +I +QR Sbjct: 509 TKIQKNESDNQRQNSESQLSQ-IIEKQKVQLQQANAIIQDLNNQIEQFQQNIQDQEEQR- 566 Query: 1233 FEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQV 1292 + + + L ++E+ E ++ + K +Q++ Q +++++ + + + Sbjct: 567 MSVISVKQSLLIEKESQINMLESQVIKYQNELTQKQDQIIILQQQYEKQKSDFNLAISE- 625 Query: 1293 TSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDL 1352 +N ++H + LQ K +D+ ++ LRS ++ +V L Sbjct: 626 -KEKNAKLTNQQH-QELQNKVSDLTFEVNQLRSLVDKAEVDKESNIQQYNEANQQLKDQL 683 Query: 1353 RTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELK 1412 T+N +++QE + ++E L+KS+ +N + ++ +L + L + Sbjct: 684 NTQNSLIQELQEYLKESNSKEQLALQKST--------QQSLEINQLQLEIGKLKNDLSQQ 735 Query: 1413 DSEIYQKTHEYTITLTQ---RNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHEN 1469 + + Q E + L + +N+ +N +Q+ + +++ ++ ++ L++K+ E+ Sbjct: 736 EQKQSQTNLENSYKLKEQQTQNETLKNDFKQIQLVQDKLKQENFQLNEQINDLQIKLQES 795 Query: 1470 ANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQ 1529 + + + +E ++ +L ++LN ++ + + V + K +++ + ++ Q ++ Sbjct: 796 QENLKQTTQINENQKEQL-QKLNDQLYQE-QQKESVNQTEKFYLQQLIQQHKDQVNEVHE 853 Query: 1530 EIEIVTLNDEITNLQ-NMVRASSSKIQKHVSFASDTKQGRDEQL 1572 + +++T E + Q ++ QKH T+ QL Sbjct: 854 KNKLITSISESKDKQIEALKKQGEDAQKHYEQQKQTQYEEMVQL 897 Score = 58.4 bits (135), Expect = 2e-06 Identities = 115/656 (17%), Positives = 272/656 (41%), Gaps = 69/656 (10%) Query: 980 ELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSY 1039 E N+++++ + Q +P +Q K + + +++ N + N +S Sbjct: 7 EANRLSVKQLAGRFQSMMKAAPVQQQQQPPP-RKSEVIARNPQQQL--QNMEETNKVLSK 63 Query: 1040 MSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETK 1099 + +V + E + + +E++++ ++ + K Q ++LQ + DQ+K +E+K Sbjct: 64 LEVVENDEDSNQRSSETVESLQKVIENLQKDCNKKDQKIQDLQENLVIMSDQMK-FRESK 122 Query: 1100 LTFEMNIPKTEGMIISSTIEPMSDDAN--NVDXXXXXXXXXXXXLKVQE-EEEFIQERSV 1156 + E+ E + + + VD ++Q+ + Q +++ Sbjct: 123 IREEVQQETKETSEFGNERVKLITELRKCQVDLQESQKQNANKFSQIQQLTNKATQIQNL 182 Query: 1157 LQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLST 1216 + + KL + QE K++Q + +L ++I +LK QLN ++ + Sbjct: 183 SKLEIDKLKQQNQELEEKLLQSQQKVDQLA-------QKIEELKELNSQLNLQSQEVEDV 235 Query: 1217 VAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEH-ELRVQLSAFESKYEQLLDSV 1275 +L D+ FEI +Q + + ++ + L+++ +A ++ + Sbjct: 236 KQKLEKEFQQRYDEVEFEIINN-RQIIEDLQIQLKELKALNLQLESAAINGTFD--MKQQ 292 Query: 1276 QSSTQEETNKIVTMEQVTSLQNKLQDKE---EHLRNLQEKYADVINQIEI-LRSEIEDEK 1331 S Q++TN++ Q LQ KL K+ + + + + + + Q +I L+ E+E K Sbjct: 293 ISLLQDQTNELQNQNQ--ELQQKLHAKQIEFDQMNKAKSREIEKLKQDKIELQQELEQTK 350 Query: 1332 VAFXXXXXXXXXXXXXXXXDL-----RTENQSYKQMQEQSILNIN--EENAQLKKSSXXX 1384 L ++E Q+ K Q+ L+ + +E K + Sbjct: 351 QISEQTQAETESNYKNQMLILQDKFQKSEEQTSKLNQKIQELSADLIQERMLYKNNESQL 410 Query: 1385 XXXXXXXXXRVNDAEAKVLELTHQLE-LKDSEIYQKTH------EYTITLTQRNDEFENV 1437 ++ + VL+LT ++ L+D + Q+T+ +Y + L Q N + + Sbjct: 411 NGVITQQKDELSQKSSLVLQLTEKIRILQDHSMQQETNISKNIDDYKVLLDQNNQQITQL 470 Query: 1438 RQQLVEYEKRIEDLTYEKESELA------------ILRLKMHENANHYETMQKESEIERV 1485 +Q+ +K+ E + ++ I + K+ +N + + ES++ ++ Sbjct: 471 SEQIKSLKKQQRQQEQENKQVISQYEQQIKQYLAEITQTKIQKNESDNQRQNSESQLSQI 530 Query: 1486 KLIEELNVKITES----VSLNKQVAELNKAL----EEEVAKTNEMQTALENQEIEIVTLN 1537 IE+ V++ ++ LN Q+ + + + E+ ++ + Q+ L +E +I L Sbjct: 531 --IEKQKVQLQQANAIIQDLNNQIEQFQQNIQDQEEQRMSVISVKQSLLIEKESQINMLE 588 Query: 1538 DEITNLQNMVRASSSKI----QKHVSFASD-----TKQGRDEQLDNTMNKELLDAV 1584 ++ QN + +I Q++ SD +++ ++ +L N ++EL + V Sbjct: 589 SQVIKYQNELTQKQDQIIILQQQYEKQKSDFNLAISEKEKNAKLTNQQHQELQNKV 644 >UniRef50_A2E8H6 Cluster: Viral A-type inclusion protein, putative; n=1; Trichomonas vaginalis G3|Rep: Viral A-type inclusion protein, putative - Trichomonas vaginalis G3 Length = 2458 Score = 188 bits (458), Expect = 1e-45 Identities = 313/1486 (21%), Positives = 651/1486 (43%), Gaps = 118/1486 (7%) Query: 154 KDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXED 213 ++N L+ + + ++ I +L+E++N+K+ + +N + Sbjct: 660 EENESEELKSENENLKKQIEELKEQLNQKEDQGQEENGWCNENETEDLKSEIEQLKKENE 719 Query: 214 TKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEIS-LEHS 272 T +Q + + +++ + ++ K++L K E + + E N+ E + +IS LE+ Sbjct: 720 TLKQNNETE----SLKKQIEELKEQL-KQKEDQGQEENGWGEENET-EDYKSQISALENE 773 Query: 273 K--LAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIEL 330 K L ++++ L +Q E + + + S+E N TE +KI Sbjct: 774 KRTLNKKIKDLANGLKTLKSKNEKLEQQLKENANNGNNDNSKDISVEF-NETE--EKITE 830 Query: 331 LEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLIS--RKSGRNTASKMKSPWSQ 388 LE N ++R+ N+ L + T+ ++ + S +K S +S R+ + S ++ Sbjct: 831 LEFENEELRRNNESLSEEKKTLHKQNNKLVSENKTLSDEVSTLREQVEELEEETISTSNE 890 Query: 389 LSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTL 448 L SE + ++ + + E+ + + ++N + + V S++ + L Sbjct: 891 LRSEIEHLRSELVVREQELEQTKNNNNNVNNNENNNSNVHSDQSIYEEKISLLKQQLEEL 950 Query: 449 I-AQLQLEHQQHMEGPSLIHVGTNTEDVN-EIAKVQEQLKQ--ELNDEIKDVNVKDLIEK 504 +Q + + +E + I + ED+ E +Q QL + E N+ + +D I K Sbjct: 951 KQSQSSNNNNEELEKEN-ISLKKEIEDLKQENEGLQNQLFEGGETNEN-NNQEKEDEIHK 1008 Query: 505 LKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQ-KTIDNF-SKVSDSNKEIVRLTE 562 LKS +I +L +++++ +N K + N+ + + + IDN S++ + NK++ + Sbjct: 1009 LKS---EIEELKKKLESSEQN--KEEENNGWGDENTETENIDNLKSEIEELNKKLDESIK 1063 Query: 563 ELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIE--MENLAETRLKAISLLE 620 +K+ E+++E LQ L + +S I +K +E + L E+ K L + Sbjct: 1064 SNDEKQKKIEEMKQENEELQTQLFENNSEEEINK--FKSQVEELTQKLQESNQKNEEL-Q 1120 Query: 621 SQKFDLVQELHILQQKYDEVEDKLA-DISQLQSDQVCSEIKSVHLEEQIDALSASKKELA 679 SQ E+ L+++ +E +KL +IS L++ EI + +E+ + K+ Sbjct: 1121 SQTEKQNNEIDDLKKQKEEENEKLQKEISDLKN-----EISQLQQKEEENGSDLQKQIEV 1175 Query: 680 LVIENLKLDK--EQLYGTIKDLENDKE---DIMNKLQNYIQENMDLTDKLEKMSAEKISE 734 L N K D+ EQL I +L+ +KE + +N L++ +Q ++ + EK E I + Sbjct: 1176 LKQTNEKNDEDIEQLAKQIDELQTEKEKQNEEINDLKSQLQNVSEIKSENEKQKNE-IDD 1234 Query: 735 LLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRI-----CRLEESIAVME 789 L +E ++QTQ QE++ I ++SE+ + K ++ + EE+I ++ Sbjct: 1235 L-----KKENEELQTQLFEIGNNQEKEEEIHKLKSEIEELKKKLEESEQNKEEENIDNLK 1289 Query: 790 DRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENK 849 +L+ + +L S ++ +K SE QE++ +++ + E+ E+E++ Sbjct: 1290 SENETLKEEIKRLESDNEQLKKQNSELQ-QENKSLHQ-----QQSKEEEENGWGEENESE 1343 Query: 850 ELQKKNQILLEENQNLQISLS---DMQQHYNALVEKANRTDLAESESTKYQTQLRDLESN 906 EL+ +N+ L ++ + L+ L D Q N ++ N T+ +S+ + + + R L Sbjct: 1344 ELKSENESLKKQIEELKEQLKQKEDQGQEENGWGDE-NETEDYKSQISALENEKRTLNKK 1402 Query: 907 LKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQE 966 +K + + +TL K +++E + N+ S + K ++ ++ + E +T+LE + +E Sbjct: 1403 IKDLANGLKTL-KSKNEKLEQQLKDINSN-NSTNDNSKDISVEFNETEEKITELEFENEE 1460 Query: 967 YKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEII 1026 + N E+L+ + L K N +K V + +T S +E++ L +++ +EE I Sbjct: 1461 LRRNNESLSEEKKTLQKQN----NKLVSENKTLS--------DEVSTLREQVEELEEETI 1508 Query: 1027 ALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVR 1086 + + ++ + S + E +L Q N+ S D + E++ +L + Sbjct: 1509 STSNELRSEIEHLRSELVLREQELEQTKNNNNNVNNNENNNSNVHSDQSIYEEKISLL-K 1567 Query: 1087 EQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQE 1146 +Q +++K+ ++ E N E + IE + + + ++ Sbjct: 1568 QQLEELKQQQQKPFDHEDNNDSDEINKLKKEIEDLKQENEELQNQLFEGGETNENNNQEK 1627 Query: 1147 EEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQL 1206 E+E + +S ++E KL + Q + NTE + + E I +L KL +L Sbjct: 1628 EDEIHKLKSEIEELKKKLESSEQNKEEENNGWGDENTETENIENLKSE-IEELNKKLNEL 1686 Query: 1207 NTENDNLLSTVAELRSSISSAVDQRGFEIAEL--WKQHLAQREADF-------QKTEHEL 1257 + ND + EL + + + + E + K+ L Q D Q+ L Sbjct: 1687 SKSNDEKQKKIEELEQKLQESQNNKDEEEENIEDLKEQLEQLRRDAITKSKQDQEEIENL 1746 Query: 1258 RVQLSAFESKYEQLLDSVQSSTQEETNKIVT-MEQVTSLQNKLQDKEEHLRNLQEKYADV 1316 + Q+ E+ E++ + ++ ++ K E++ LQN++Q ++E + NL + D Sbjct: 1747 KKQIEEKEADIEEITEELEQLRKDSITKAKQDQEEIEKLQNEIQKQKEIIDNLNAEI-DE 1805 Query: 1317 INQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQ 1376 + + E +++DE L E + K E NI ++ Sbjct: 1806 LGEKEAEHEDLKDELQQLRKDSLQKAKIDQAEIDRLNAEVSNLKFELENGKENIWGDDDD 1865 Query: 1377 LKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQL-ELKD-SEIYQKTHEYTITLTQR---- 1430 +K + D +++ +L ++ + +D +E+ Q+ + L Q Sbjct: 1866 NEKHKETLTEIIEKLKSEIEDKNSEIEKLEEEISQFEDPTEVKQENKKLKEELDQALRQN 1925 Query: 1431 ------NDEFENVRQQLVEYEKRIEDLTYEKE-SELAILRLKMHENAN--HYETMQKESE 1481 N+E +R+QL + E T EK+ E K+H++ N +E + Sbjct: 1926 AELGNVNEENNKLREQLKQSIDTNELKTLEKKLKEKEEENQKLHDDLNTLQFELNNSIAG 1985 Query: 1482 IERVKLIEELNVK--ITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDE 1539 + ++ E + ++ + + NK+++EL K LEEE N + + LEN +V ND Sbjct: 1986 LPKINQSESMEIRDEVERLANENKKLSELTKKLEEE---KNFLVSQLEN----VVQRNDY 2038 Query: 1540 ITNLQNMVRASSSKIQKHVSFASDTKQGRDE--QLDNTMNKELLDA 1583 LQN V K++K + Q DE + + T N E DA Sbjct: 2039 EKELQN-VEELKLKLKKAEKDNEELLQQIDELVEQNETENHEKSDA 2083 Score = 176 bits (429), Expect = 4e-42 Identities = 311/1489 (20%), Positives = 627/1489 (42%), Gaps = 141/1489 (9%) Query: 153 EKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXE 212 +KD + + ++ ++ L+++I +KDQ I N T E Sbjct: 265 QKDASSDDKNSDLSRLKKAVVQLKKQIAQKDQEI---NDLKTSNMQLQNFNNETQNVEIE 321 Query: 213 DTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLE--AARFEISLE 270 K Q+ + Q+ +++AE + ++ I L++ N L+ E Sbjct: 322 KYKSQIIEFQKIIESLKAENAKLQTENTNTVDKLQSEIEKLKQENSELQNQIQENEDGWN 381 Query: 271 HSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIEL 330 + +EL+ K+S E+ +I + S +I ++ + + + Sbjct: 382 DNNNEEELQNQITELQKQLEEN----KKSYSEETEQLKQIIDDDSKQIEDLKQKLAEAQD 437 Query: 331 LE-HLNCQIR--QTNKE-LENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPW 386 E + + Q+ QT K+ L+ KL + + + + + IS+ + N S ++ Sbjct: 438 HEGNSDSQLAKLQTEKQQLDKKLVDVANALRKLKTKNDNDQATISKLNEEN--SSLQKQI 495 Query: 387 SQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKD 446 +L +T N + + EI L+ +Q L + + + +E + ++ Sbjct: 496 EELKQQTANNASYEA----EIQNLKKQLQDLQ---IQNDDIKTENEHLQQEMFENNKSEE 548 Query: 447 TLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLK---QELNDEIKDVNVKDLI- 502 + Q+ Q + +++ + K EQ+K QELN+E+ N + Sbjct: 549 IEQQKKQISELQKEISSKSSEIQAKNDEIENLNKEIEQIKKENQELNEELFQNNENNSND 608 Query: 503 EKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSN-----KEI 557 E+++ + QI L EI ++ + +N+K +++++++ ++ D N E Sbjct: 609 EEIEKLKTQIQSLQKEIS----DLSQQNNNYKSQVEELKEELEKHQSEQDENGWGEENES 664 Query: 558 VRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETR--LKA 615 L E +L +++ EL+E+ N + ++G E++ E+E L + LK Sbjct: 665 EELKSENENLKKQIEELKEQL-NQKEDQGQEENGWCNENETEDLKSEIEQLKKENETLKQ 723 Query: 616 ISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASK 675 + ES K + + L+QK D+ +++ + +++ S+I + LE + L+ Sbjct: 724 NNETESLKKQIEELKEQLKQKEDQGQEENGWGEENETEDYKSQISA--LENEKRTLNKKI 781 Query: 676 KELALVIENLKLDKEQLYGTIKDLEND-----KEDI---MNKLQNYIQE----NMDLTDK 723 K+LA ++ LK E+L +K+ N+ +DI N+ + I E N +L Sbjct: 782 KDLANGLKTLKSKNEKLEQQLKENANNGNNDNSKDISVEFNETEEKITELEFENEELRRN 841 Query: 724 LEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESEL----SKYKSRIC 779 E +S EK + L K N++ S+ +T + ++E+ +E +E E ++ +S I Sbjct: 842 NESLSEEK--KTLHKQNNKLVSENKTLSDEVSTLREQ---VEELEEETISTSNELRSEIE 896 Query: 780 RLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDE--LVNRLAVLMDHDRVV 837 L + V E + + + + +S+ +I E++ L+ + + + Sbjct: 897 HLRSELVVREQELEQTKNNNNNVNNNENNNSNVHSDQSIYEEKISLLKQQLEELKQSQSS 956 Query: 838 EKQLLEIEHENKELQKKNQILLEENQNLQISLSDM-QQHYNALVEKANRTDLAESESTKY 896 E+E EN L+K+ + L +EN+ LQ L + + + N EK + +SE + Sbjct: 957 NNNNEELEKENISLKKEIEDLKQENEGLQNQLFEGGETNENNNQEKEDEIHKLKSEIEEL 1016 Query: 897 QTQLRDLESNLKRITH---EHQTL---IVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKY 950 + +L E N + + + T I K EIE+L + + I+S +K + E Sbjct: 1017 KKKLESSEQNKEEENNGWGDENTETENIDNLKSEIEELNKKLDESIKSNDEKQKKIEEMK 1076 Query: 951 EKNIEYVTQL-----EAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTE 1005 ++N E TQL E ++ ++K+ +E L ++E N+ N EL Q+Q TE Sbjct: 1077 QENEELQTQLFENNSEEEINKFKSQVEELTQKLQESNQKNEEL--------QSQ----TE 1124 Query: 1006 QYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQ 1065 + NEI+ L KQK+EE N+K+ +SD +++++Q K E ++Q Sbjct: 1125 KQNNEIDDLK---KQKEEE----NEKLQKE-------ISDLKNEISQLQQKEEENGSDLQ 1170 Query: 1066 RVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDA 1125 + + L + + N+E + +Q D+++ KE K E+N K++ +S Sbjct: 1171 KQIEVLKQTNEKNDEDIEQLAKQIDELQTEKE-KQNEEINDLKSQLQNVSEIKSENEKQK 1229 Query: 1126 NNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTEL 1185 N +D L+ Q E I +E+ KL +E++E K+ + E N E Sbjct: 1230 NEIDDLKKENEE----LQTQLFE--IGNNQEKEEEIHKLKSEIEELKKKLEESEQ-NKEE 1282 Query: 1186 TGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAEL-WKQHLA 1244 D + E LK ++++L ++N+ L +EL+ S Q+ E E W + Sbjct: 1283 ENIDNLKSEN-ETLKEEIKRLESDNEQLKKQNSELQQENKSLHQQQSKEEEENGWGE--- 1338 Query: 1245 QREADFQKTEHE-LRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKE 1303 + E++ K+E+E L+ Q+ + + +Q D Q E N + ++++ E Sbjct: 1339 ENESEELKSENESLKKQIEELKEQLKQKEDQGQ-----EENGWGDENETEDYKSQISALE 1393 Query: 1304 EHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQ 1363 R L +K D+ N ++ L+S+ +EK+ D+ E Sbjct: 1394 NEKRTLNKKIKDLANGLKTLKSK--NEKLEQQLKDINSNNSTNDNSKDISVEFNE----T 1447 Query: 1364 EQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEY 1423 E+ I + EN +L++++ + N ++ L+ ++ ++ + E Sbjct: 1448 EEKITELEFENEELRRNNESLSEEKKTLQKQNNKLVSENKTLSDEVSTLREQVEELEEET 1507 Query: 1424 TITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENAN-HYETMQKESEI 1482 T + E E++R +LV E+ +E + + + N+N H + E +I Sbjct: 1508 ISTSNELRSEIEHLRSELVLREQELEQTKNNNNN----VNNNENNNSNVHSDQSIYEEKI 1563 Query: 1483 ERVKL-IEELNVKIT-----ESVSLNKQVAELNKALEEEVAKTNEMQTAL----ENQEIE 1532 +K +EEL + E + + ++ +L K +E+ + E+Q L E E Sbjct: 1564 SLLKQQLEELKQQQQKPFDHEDNNDSDEINKLKKEIEDLKQENEELQNQLFEGGETNENN 1623 Query: 1533 IVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELL 1581 DEI L++ + K++ + G ++ T N E L Sbjct: 1624 NQEKEDEIHKLKSEIEELKKKLESSEQNKEEENNGWGDENTETENIENL 1672 Score = 169 bits (410), Expect = 7e-40 Identities = 258/1233 (20%), Positives = 541/1233 (43%), Gaps = 104/1233 (8%) Query: 405 NEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPS 464 NE+A+ + I+ K + D I G + ++ + + + + +E + Sbjct: 66 NELAECDKKIEEKEKLIEDLAKEIENMKNTTSTASQNDSGLEEVVQEFE-QKIETLESEN 124 Query: 465 LIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVK--DLIEKLKSAEEQITQLNDEIDAA 522 N+E +I + +E L +L+ E ++ K ++ + KSAEE + Q + D Sbjct: 125 KTMKDQNSELQQQIQQYKE-LTDKLSTESTELQQKMENIKSEDKSAEETLLQTISDQDIQ 183 Query: 523 NKNMIKVKSNHKLKLKQMQKTIDNFS-KVSDSNKEIVRLTEEL---HHLSQKVAELEEEK 578 + + KL ++ + F+ K + N +I L +L LS ++A L+ + Sbjct: 184 INKLKEELEQAKLAANSSEQNTNAFAQKEQELNAQITDLKNQLAAKDSLSDEIASLKAQI 243 Query: 579 GNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYD 638 L + +S E++ K + + ++ + +S L+ L +++ QK Sbjct: 244 AELNQN----NSKSSEENEQLKAESQKDASSDDKNSDLSRLKKAVVQLKKQI---AQKDQ 296 Query: 639 EVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKEL-ALVIENLKLDKEQLYGTIK 697 E+ D QLQ+ +E ++V +E+ + +K + +L EN KL E T+ Sbjct: 297 EINDLKTSNMQLQNFN--NETQNVEIEKYKSQIIEFQKIIESLKAENAKLQTENT-NTVD 353 Query: 698 DLENDKEDIM---NKLQNYIQENMD--LTDKLEKMSAEKISELLAKINHEEQSKIQTQFG 752 L+++ E + ++LQN IQEN D + E+ +I+EL ++ ++S + Sbjct: 354 KLQSEIEKLKQENSELQNQIQENEDGWNDNNNEEELQNQITELQKQLEENKKSYSEETEQ 413 Query: 753 IDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKA 812 + I + IE+++ +L++ + + +A ++ + L++K + + L+ K K Sbjct: 414 LKQIIDDDSKQIEDLKQKLAEAQDHEGNSDSQLAKLQTEKQQLDKKLVDVANALR-KLKT 472 Query: 813 YSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHE---NKELQKKNQILLEENQNLQISL 869 ++ D+ ++ L + + ++KQ+ E++ + N + + Q L ++ Q+LQI Sbjct: 473 KND----NDQAT--ISKLNEENSSLQKQIEELKQQTANNASYEAEIQNLKKQLQDLQIQN 526 Query: 870 SDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDL- 928 D++ L ++ + +E E + + Q+ +L+ + + E Q K EIE+L Sbjct: 527 DDIKTENEHLQQEMFENNKSE-EIEQQKKQISELQKEISSKSSEIQA----KNDEIENLN 581 Query: 929 -EIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENL---NMNVEELNKM 984 EIE + + ++ N + N E + +L+ Q+Q + I +L N N + + Sbjct: 582 KEIEQIKKENQELNEELFQNNENNSNDEEIEKLKTQIQSLQKEISDLSQQNNNYKSQVEE 641 Query: 985 NLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIA-LNQKINNAQVSYMSMV 1043 E ++KH Q +Q ++ E E+ N LK++ EE+ LNQK + Q Sbjct: 642 LKEELEKH-QSEQDENGWGEENESEELKSENENLKKQIEELKEQLNQKEDQGQEEN-GWC 699 Query: 1044 SDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNE--ELQILVREQDDQIKELKETKLT 1101 ++ E+ E+++ E++++ K+ KQ+NE L+ + E +Q+K+ ++ Sbjct: 700 NENET---------EDLKSEIEQLKKENETLKQNNETESLKKQIEELKEQLKQKEDQGQE 750 Query: 1102 FEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEE--EEFIQERSVL-- 1157 + E S I + ++ ++ LK + E E+ ++E + Sbjct: 751 ENGWGEENETEDYKSQISALENEKRTLNKKIKDLANGLKTLKSKNEKLEQQLKENANNGN 810 Query: 1158 QEQSAKLNTELQECYTKIIQLETLNTELT-GHDVVNQE------QINQLKSKLEQLNTEN 1210 + S ++ E E KI +LE N EL ++ +++E Q N+L S+ + L+ E Sbjct: 811 NDNSKDISVEFNETEEKITELEFENEELRRNNESLSEEKKTLHKQNNKLVSENKTLSDEV 870 Query: 1211 DNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHE-------------L 1257 L V EL S ++ EI L + L RE + ++T++ + Sbjct: 871 STLREQVEELEEETISTSNELRSEIEHL-RSELVVREQELEQTKNNNNNVNNNENNNSNV 929 Query: 1258 RVQLSAFESKY----EQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKY 1313 S +E K +QL + QS + N+ + E + SL+ +++D ++ LQ + Sbjct: 930 HSDQSIYEEKISLLKQQLEELKQSQSSNNNNEELEKENI-SLKKEIEDLKQENEGLQNQL 988 Query: 1314 ADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSY--KQMQEQSILNIN 1371 + E E EDE + EN + + + ++I N+ Sbjct: 989 FEGGETNENNNQEKEDEIHKLKSEIEELKKKLESSEQNKEEENNGWGDENTETENIDNLK 1048 Query: 1372 EENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSE-----IYQKTHEYTIT 1426 E +L K ++ + + + EL QL +SE + E T Sbjct: 1049 SEIEELNKKLDESIKSNDEKQKKIEEMKQENEELQTQLFENNSEEEINKFKSQVEELTQK 1108 Query: 1427 LTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESE----- 1481 L + N + E ++ Q + I+DL +KE E L+ ++ + N +Q++ E Sbjct: 1109 LQESNQKNEELQSQTEKQNNEIDDLKKQKEEENEKLQKEISDLKNEISQLQQKEEENGSD 1168 Query: 1482 -IERVKLIEELNVKITESV-SLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDE 1539 ++++++++ N K E + L KQ+ EL E++ + N++++ L+N EI + N++ Sbjct: 1169 LQKQIEVLKQTNEKNDEDIEQLAKQIDELQTEKEKQNEEINDLKSQLQNVS-EIKSENEK 1227 Query: 1540 ITNLQNMVRASSSKIQKHVSFASDTKQGRDEQL 1572 N + ++ + ++Q + F Q ++E++ Sbjct: 1228 QKNEIDDLKKENEELQTQL-FEIGNNQEKEEEI 1259 Score = 165 bits (400), Expect = 1e-38 Identities = 267/1359 (19%), Positives = 585/1359 (43%), Gaps = 118/1359 (8%) Query: 212 EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271 E+ + Q K ++ + ++E ++L K+I IS L++ + Sbjct: 1117 EELQSQTEKQNNEIDDLKKQKEEENEKLQKEISDLKNEISQLQQKEEE----------NG 1166 Query: 272 SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSL--EIANMTELTKKIE 329 S L +++E LAKQ E E++ + EE L ++ N++E+ + E Sbjct: 1167 SDLQKQIEVLKQTNEKNDEDIEQLAKQIDELQTEKEKQNEEINDLKSQLQNVSEIKSENE 1226 Query: 330 LLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPL--ISRKSGRNTASKMKSPWS 387 ++ +++ N+EL+ +L +G + K S + + +K + +K + Sbjct: 1227 KQKNEIDDLKKENEELQTQLFEIGNNQEKEEEIHKLKSEIEELKKKLEESEQNKEEENID 1286 Query: 388 QLSSE--TLNQDTDKKINKNE-IAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXG 444 L SE TL ++ + + NE + K +Q NK L ++ E++ Sbjct: 1287 NLKSENETLKEEIKRLESDNEQLKKQNSELQQENKSLHQQQSKEEEENGWGEENESEELK 1346 Query: 445 KDTLIAQLQLEH------QQHMEGPSLIHVG--TNTEDVNEIAKVQEQLKQELNDEIKDV 496 + + Q+E Q+ +G G TED E K+ LN +IKD+ Sbjct: 1347 SENESLKKQIEELKEQLKQKEDQGQEENGWGDENETEDYKSQISALENEKRTLNKKIKDL 1406 Query: 497 NVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKE 556 + ++ LKS E++ Q +I++ N N K + +T + +++ N+E Sbjct: 1407 --ANGLKTLKSKNEKLEQQLKDINSNNST----NDNSKDISVEFNETEEKITELEFENEE 1460 Query: 557 IVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAI 616 + R E L S++ L+++ L + + +V ++E L E + Sbjct: 1461 LRRNNESL---SEEKKTLQKQNNKL------VSENKTLSDEVSTLREQVEELEEETISTS 1511 Query: 617 SLLESQKFDLVQELHILQQKYDEVEDKLADI-------SQLQSDQVCSEIKSVHLEEQID 669 + L S+ L EL + +Q+ ++ ++ ++ S + SDQ E K L++Q++ Sbjct: 1512 NELRSEIEHLRSELVLREQELEQTKNNNNNVNNNENNNSNVHSDQSIYEEKISLLKQQLE 1571 Query: 670 ALSASKKELALVIENLKLDK-EQLYGTIKDLENDKEDIMNKL----QNYIQENMDLTDKL 724 L +++ +N D+ +L I+DL+ + E++ N+L + N + D++ Sbjct: 1572 ELKQQQQKPFDHEDNNDSDEINKLKKEIEDLKQENEELQNQLFEGGETNENNNQEKEDEI 1631 Query: 725 EKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEES 784 K+ +E I EL K+ EQ+K + G + E + IEN++SE+ + ++ L +S Sbjct: 1632 HKLKSE-IEELKKKLESSEQNKEEENNGWGDENTETE-NIENLKSEIEELNKKLNELSKS 1689 Query: 785 IAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVL---MDHDRV----- 836 + + LE+K + + E+++ + Q ++L R A+ D + + Sbjct: 1690 NDEKQKKIEELEQKLQESQNNKDEEEENIEDLKEQLEQL-RRDAITKSKQDQEEIENLKK 1748 Query: 837 -VEKQLLEIEHENKELQ--KKNQILL-----EENQNLQISLSDMQQHYNALVEKANRTDL 888 +E++ +IE +EL+ +K+ I EE + LQ + ++ + L + + Sbjct: 1749 QIEEKEADIEEITEELEQLRKDSITKAKQDQEEIEKLQNEIQKQKEIIDNLNAEIDELGE 1808 Query: 889 AESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNE 948 E+E + +L+ L + + Q I + E+ +L+ E E+ D NE Sbjct: 1809 KEAEHEDLKDELQQLRKDSLQKAKIDQAEIDRLNAEVSNLKFELENGKENIWGDDDD-NE 1867 Query: 949 KYEKNI-EYVTQLEAQLQEYKNNIENLNMNVEEL-NKMNLELIDKHVQKQQTQSPDYTEQ 1006 K+++ + E + +L++++++ + IE L + + + ++ +K ++++ Q+ + Sbjct: 1868 KHKETLTEIIEKLKSEIEDKNSEIEKLEEEISQFEDPTEVKQENKKLKEELDQALRQNAE 1927 Query: 1007 YIN---EINKLNALLKQKDE--EIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENME 1061 N E NKL LKQ + E+ L +K+ + + D + QF +L N Sbjct: 1928 LGNVNEENNKLREQLKQSIDTNELKTLEKKLKEKEEENQKLHDDLNT--LQF--ELNNSI 1983 Query: 1062 EEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMN--IPKTEGMIISSTIE 1119 + ++++ +S + +E++ L E + ++ EL + KL E N + + E ++ + E Sbjct: 1984 AGLPKINQS--ESMEIRDEVERLANE-NKKLSELTK-KLEEEKNFLVSQLENVVQRNDYE 2039 Query: 1120 PMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLE 1179 + + L +Q+ +E +++ + + +EL+ ++ +L+ Sbjct: 2040 KELQNVEELKLKLKKAEKDNEEL-LQQIDELVEQNETENHEKSDAESELKSLKAELAKLK 2098 Query: 1180 TLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELW 1239 E V +E++++L K+E+ T N L + + + +S + + + F+ + Sbjct: 2099 DSEKEYQ----VLREEVDELTQKIEESETINKELKTIIDQNDTSAAENMYKAQFDELKAL 2154 Query: 1240 KQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKL 1299 L + D +K + +++ + +L +++ TQ+ +N +E++T+ + L Sbjct: 2155 VSDLKSQNEDLKKDSENSKQEITKLTEEKTELNANIEKLTQDNSNLSSNVEKLTNEISNL 2214 Query: 1300 QDKEEHLRNLQEKYADVINQI-----------EILRSEIEDEKVAFXXXXXXXXXXXXXX 1348 + + N+ V N++ E ++++E EK Sbjct: 2215 KFQPTAQENVVPAETPVANEVKPSEEAVSTPNEDEKAKLESEKEELVKKNDEMMKQIVLM 2274 Query: 1349 XXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQ 1408 ++ +N+ + QMQE+ + NEEN L+ +++ A VL L Sbjct: 2275 KNEIEKQNKEFAQMQER-FIKANEENMSLRN----VASKNKELETQLDQKTANVLSLRKD 2329 Query: 1409 LELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHE 1468 ++ E +QK + L + EF ++R++ E++ L + E + + + E Sbjct: 2330 IDNLKIE-FQK--DLDAKLAKAAKEFNDLRKKFRVVEQQRNQLAAQIEYDEQ--QKQTAE 2384 Query: 1469 NANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAE 1507 N ET K+ +I+ + IE L + + S +++ E Sbjct: 2385 AQNQSET--KKLQIDTFR-IEYLRATLLQFFSQDQKTQE 2420 Score = 163 bits (397), Expect = 3e-38 Identities = 304/1498 (20%), Positives = 611/1498 (40%), Gaps = 138/1498 (9%) Query: 147 LSNTIKEKDNALSVLQVKMKIMETTILDLQEK---INEKDQIIEA-KNKATTXXXXXXXX 202 L+ IK+ N L L+ K + +E + + N KD +E + + Sbjct: 777 LNKKIKDLANGLKTLKSKNEKLEQQLKENANNGNNDNSKDISVEFNETEEKITELEFENE 836 Query: 203 XXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIES-KDVRISSLEEANKLLE 261 + K+ + K ++ DE L + +E ++ IS+ E +E Sbjct: 837 ELRRNNESLSEEKKTLHKQNNKLVSENKTLSDEVSTLREQVEELEEETISTSNELRSEIE 896 Query: 262 AARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSI--EPSCEEKTEIEEKGSLEIA 319 R E+ + +L Q + QSI E K ++EE + + Sbjct: 897 HLRSELVVREQELEQTKNNNNNVNNNENNNSNVHSDQSIYEEKISLLKQQLEELKQSQSS 956 Query: 320 NMT--ELTKK-IELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGR 376 N EL K+ I L + + ++Q N+ L+N+L G ++ ++ +K + KS Sbjct: 957 NNNNEELEKENISLKKEIE-DLKQENEGLQNQLFEGGETNE--NNNQEKEDEIHKLKSEI 1013 Query: 377 NTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXX 436 K Q E N D+ I L+ I+ LNK L + I D Sbjct: 1014 EELKKKLESSEQNKEEENNGWGDENTETENIDNLKSEIEELNKKLDES---IKSNDEKQK 1070 Query: 437 XXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDV 496 + L QL E+ E + + E++ + + Q +EL + + Sbjct: 1071 KIEEMKQENEELQTQL-FENNSEEE---INKFKSQVEELTQKLQESNQKNEELQSQTEKQ 1126 Query: 497 NVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKE 556 N ++ + K EE+ +L EI + +++ + +QK I+ + ++ N E Sbjct: 1127 N-NEIDDLKKQKEEENEKLQKEISDLKNEISQLQQKEEENGSDLQKQIEVLKQTNEKNDE 1185 Query: 557 IVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAI 616 ++ L++++ EL+ EK + D S S++ + + +N + K Sbjct: 1186 ------DIEQLAKQIDELQTEKEKQNEEINDLKSQLQNVSEIKSENEKQKNEIDDLKKEN 1239 Query: 617 SLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKK 676 L++Q F++ Q+K +E+ ++I +L+ SE EE ID L + + Sbjct: 1240 EELQTQLFEIGNN----QEKEEEIHKLKSEIEELKKKLEESEQNKE--EENIDNLKSENE 1293 Query: 677 ELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQEN-MDLTDKLEKMSAE----- 730 L I+ L+ D EQL +L+ + + + + +EN ++ E++ +E Sbjct: 1294 TLKEEIKRLESDNEQLKKQNSELQQENKSLHQQQSKEEEENGWGEENESEELKSENESLK 1353 Query: 731 -KISELLAKINH-EEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVM 788 +I EL ++ E+Q + + +G + + ++ I +E+E +I L + + Sbjct: 1354 KQIEELKEQLKQKEDQGQEENGWGDENETEDYKSQISALENEKRTLNKKIKDLANGLKTL 1413 Query: 789 EDRRYSLERKADQLGSY-------------LQEKQKAYSEYTIQEDELVNRLAVLMDHDR 835 + + LE++ + S E ++ +E + +EL L + + Sbjct: 1414 KSKNEKLEQQLKDINSNNSTNDNSKDISVEFNETEEKITELEFENEELRRNNESLSEEKK 1473 Query: 836 VVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLA----ES 891 ++KQ ++ ENK L + L E+ + L+ + +E R++L E Sbjct: 1474 TLQKQNNKLVSENKTLSDEVSTLREQVEELEEETISTSNELRSEIEHL-RSELVLREQEL 1532 Query: 892 ESTKYQTQLRDLESNLKRITHEHQTLIVQK----KKEIEDL--------EIEFNTQIESA 939 E TK + N H Q++ +K K+++E+L + E N + Sbjct: 1533 EQTKNNNNNVNNNENNNSNVHSDQSIYEEKISLLKQQLEELKQQQQKPFDHEDNNDSDEI 1592 Query: 940 IRDKKVLNEKYEKNIEYVTQL-------EAQLQEYKNNIENLNMNVEELNKMNLELIDKH 992 + KK + + ++N E QL E QE ++ I L +EEL K LE +++ Sbjct: 1593 NKLKKEIEDLKQENEELQNQLFEGGETNENNNQEKEDEIHKLKSEIEELKK-KLESSEQN 1651 Query: 993 VQKQ---------QTQSPDYTEQYINEINK-LNALLKQKDEE---IIALNQKINNAQVSY 1039 +++ +T++ + + I E+NK LN L K DE+ I L QK+ +Q + Sbjct: 1652 KEEENNGWGDENTETENIENLKSEIEELNKKLNELSKSNDEKQKKIEELEQKLQESQNNK 1711 Query: 1040 ---MSMVSDYESKLAQFT----TKLENMEEEMQRVSKQLLDSKQHNEEL-QILVREQDDQ 1091 + D + +L Q TK + +EE++ + KQ+ + + EE+ + L + + D Sbjct: 1712 DEEEENIEDLKEQLEQLRRDAITKSKQDQEEIENLKKQIEEKEADIEEITEELEQLRKDS 1771 Query: 1092 IKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFI 1151 I + K+ + E + E I+ ++ + + + L+ Q ++ + Sbjct: 1772 ITKAKQDQEEIEKL--QNEIQKQKEIIDNLNAEIDELGEKEAEHEDLKDELQ-QLRKDSL 1828 Query: 1152 QERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTEND 1211 Q+ + Q + +LN E+ +LE + G D N++ L +E+L +E + Sbjct: 1829 QKAKIDQAEIDRLNAEVSNLK---FELENGKENIWGDDDDNEKHKETLTEIIEKLKSEIE 1885 Query: 1212 NLLSTVAELRSSIS-----SAVDQRGFEIAELWKQHLAQRE--ADFQKTEHELRVQLS-A 1263 + S + +L IS + V Q ++ E Q L Q + + ++LR QL + Sbjct: 1886 DKNSEIEKLEEEISQFEDPTEVKQENKKLKEELDQALRQNAELGNVNEENNKLREQLKQS 1945 Query: 1264 FESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEIL 1323 ++ + L+ +EE K+ + + +LQ +L + L + + + I E+ Sbjct: 1946 IDTNELKTLEKKLKEKEEENQKL--HDDLNTLQFELNNSIAGLPKINQSESMEIRD-EVE 2002 Query: 1324 RSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSY-KQMQEQSILNIN-----EENAQL 1377 R E++K++ + + Y K++Q L + ++N +L Sbjct: 2003 RLANENKKLSELTKKLEEEKNFLVSQLENVVQRNDYEKELQNVEELKLKLKKAEKDNEEL 2062 Query: 1378 KKSSXXXXXXXXXXXXRVNDAEAKVLELTHQL-ELKDSEI-YQKTHEYTITLTQRNDEFE 1435 + +DAE+++ L +L +LKDSE YQ E LTQ+ +E E Sbjct: 2063 LQQIDELVEQNETENHEKSDAESELKSLKAELAKLKDSEKEYQVLREEVDELTQKIEESE 2122 Query: 1436 NVRQQLVEYEKRIEDLTYEK--ESELAILRLKMHENANHYETMQKESEIERVKLIEELNV 1493 + ++L + + E +++ L+ + + + E ++K+SE + ++ Sbjct: 2123 TINKELKTIIDQNDTSAAENMYKAQFDELKALVSDLKSQNEDLKKDSENSKQEI-----T 2177 Query: 1494 KITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASS 1551 K+TE + ELN +E+ + + + +E EI L + T +N+V A + Sbjct: 2178 KLTE------EKTELNANIEKLTQDNSNLSSNVEKLTNEISNLKFQPTAQENVVPAET 2229 Score = 163 bits (395), Expect = 5e-38 Identities = 283/1372 (20%), Positives = 579/1372 (42%), Gaps = 122/1372 (8%) Query: 295 LAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGT 354 LAK+ T + LE + E +KIE LE N ++ N EL+ ++ Sbjct: 85 LAKEIENMKNTTSTASQNDSGLEEV-VQEFEQKIETLESENKTMKDQNSELQQQI----Q 139 Query: 355 ESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVI 414 + K ++ S + +K N S+ KS L +QD K E+ + ++ Sbjct: 140 QYKELTDKLSTESTELQQKM-ENIKSEDKSAEETLLQTISDQDIQINKLKEELEQAKLAA 198 Query: 415 QSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTED 474 S ++ E + KD+L ++ Q E L + + + Sbjct: 199 NSSEQNTNAFAQKEQELNAQITDLKNQLAAKDSLSDEIASLKAQIAE---LNQNNSKSSE 255 Query: 475 VNEIAKVQEQLKQELNDEIKDVN-VKDLIEKLKSAEEQITQLNDEI-DAANKNMIKVKSN 532 NE K + Q +D+ D++ +K + +LK +QI Q + EI D NM N Sbjct: 256 ENEQLKAESQKDASSDDKNSDLSRLKKAVVQLK---KQIAQKDQEINDLKTSNMQLQNFN 312 Query: 533 HK---LKLKQMQKTIDNFSKVSDSNK-EIVRL----TEELHHLSQKVAELEEEKGNLQLH 584 ++ +++++ + I F K+ +S K E +L T + L ++ +L++E LQ Sbjct: 313 NETQNVEIEKYKSQIIEFQKIIESLKAENAKLQTENTNTVDKLQSEIEKLKQENSELQNQ 372 Query: 585 LVDYDSG---RMIESDVYKKMIEMENLAETRLKAISLLESQKFDLV----QELHILQQKY 637 + + + G E ++ ++ E++ E K+ S Q ++ +++ L+QK Sbjct: 373 IQENEDGWNDNNNEEELQNQITELQKQLEENKKSYSEETEQLKQIIDDDSKQIEDLKQKL 432 Query: 638 DEVED----KLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLY 693 E +D + +++LQ+++ + K V + + L I L + L Sbjct: 433 AEAQDHEGNSDSQLAKLQTEKQQLDKKLVDVANALRKLKTKNDNDQATISKLNEENSSLQ 492 Query: 694 GTIKDL----------ENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEE 743 I++L E + +++ +LQ+ +N D+ + E + E ++ ++ Sbjct: 493 KQIEELKQQTANNASYEAEIQNLKKQLQDLQIQNDDIKTENEHLQQEMFENNKSEEIEQQ 552 Query: 744 QSKI-QTQFGIDAK---IQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKA 799 + +I + Q I +K IQ ++ IEN+ E+ + K L E + + S + + Sbjct: 553 KKQISELQKEISSKSSEIQAKNDEIENLNKEIEQIKKENQELNEEL-FQNNENNSNDEEI 611 Query: 800 DQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILL 859 ++L + +Q QK S+ + Q + +++ L + +EK E + + +++ L Sbjct: 612 EKLKTQIQSLQKEISDLSQQNNNYKSQVEELKEE---LEKHQSEQDENGWGEENESEELK 668 Query: 860 EENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTL-- 917 EN+NL+ + ++++ N ++ E + + DL+S ++++ E++TL Sbjct: 669 SENENLKKQIEELKEQLNQKEDQGQ-----EENGWCNENETEDLKSEIEQLKKENETLKQ 723 Query: 918 ---IVQKKKEIEDLEIEFNTQIESAIRD----KKVLNEKYEKNIEYVTQ----LEAQLQE 966 KK+IE+L+ + + + + ++ E Y+ I + L ++++ Sbjct: 724 NNETESLKKQIEELKEQLKQKEDQGQEENGWGEENETEDYKSQISALENEKRTLNKKIKD 783 Query: 967 YKNNIENL---NMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDE 1023 N ++ L N +E+ K N + K + + TE+ I E+ N L++ +E Sbjct: 784 LANGLKTLKSKNEKLEQQLKENANNGNNDNSKDISVEFNETEEKITELEFENEELRRNNE 843 Query: 1024 EIIALNQ---KINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEE 1080 + + K NN VS +SD S L + ++E +EEE S +L +H Sbjct: 844 SLSEEKKTLHKQNNKLVSENKTLSDEVSTLRE---QVEELEEETISTSNELRSEIEHLRS 900 Query: 1081 LQILVREQD-DQIK---------ELKETKLTFEMNIPKTEGMIISSTIEPM----SDDAN 1126 +++VREQ+ +Q K E + + + +I + + ++ +E + S + N Sbjct: 901 -ELVVREQELEQTKNNNNNVNNNENNNSNVHSDQSIYEEKISLLKQQLEELKQSQSSNNN 959 Query: 1127 NVDXXXXXXXXXXXXLKVQEEEEFIQERSVL-QEQSAKLNTELQECYTKI-IQLETLNTE 1184 N + +++E E +Q + E + N E ++ K+ ++E L + Sbjct: 960 NEELEKENISLKKEIEDLKQENEGLQNQLFEGGETNENNNQEKEDEIHKLKSEIEELKKK 1019 Query: 1185 LTGHDVVNQEQINQLKSKLEQLNTEN-DNLLSTVAELRSSISSAVDQRGFEIAELWKQHL 1243 L + +E+ N E TEN DNL S + EL + ++ + ++ + Sbjct: 1020 LESSEQNKEEENNGWGD--ENTETENIDNLKSEIEELNKKLDESIKSNDEKQKKIEEMKQ 1077 Query: 1244 AQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQE-ETNKIVTMEQVTSLQNKLQDK 1302 E Q E+ +++ F+S+ E+L +Q S Q+ E + T +Q + + + K Sbjct: 1078 ENEELQTQLFENNSEEEINKFKSQVEELTQKLQESNQKNEELQSQTEKQNNEIDDLKKQK 1137 Query: 1303 EEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQM 1362 EE LQ++ +D+ N+I L+ + E+ D+ + ++ Sbjct: 1138 EEENEKLQKEISDLKNEISQLQQKEEENGSDLQKQIEVLKQTNEKNDEDIEQLAKQIDEL 1197 Query: 1363 Q---EQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQL------ELKD 1413 Q E+ IN+ +QL+ S ++D + + EL QL + K+ Sbjct: 1198 QTEKEKQNEEINDLKSQLQNVS-EIKSENEKQKNEIDDLKKENEELQTQLFEIGNNQEKE 1256 Query: 1414 SEIYQKTHEY-----TITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLK--- 1465 EI++ E + +++N E EN+ E E E++ ES+ L+ + Sbjct: 1257 EEIHKLKSEIEELKKKLEESEQNKEEENIDNLKSENETLKEEIK-RLESDNEQLKKQNSE 1315 Query: 1466 -MHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQT 1524 EN + ++ KE E E +E+ SL KQ+ EL + L+++ + E Sbjct: 1316 LQQENKSLHQQQSKEEEENGWGEENESEELKSENESLKKQIEELKEQLKQKEDQGQEENG 1375 Query: 1525 ALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTM 1576 + E E +I+ L+N R + KI K ++ T + ++E+L+ + Sbjct: 1376 WGDENETE--DYKSQISALENEKRTLNKKI-KDLANGLKTLKSKNEKLEQQL 1424 Score = 161 bits (392), Expect = 1e-37 Identities = 296/1481 (19%), Positives = 623/1481 (42%), Gaps = 139/1481 (9%) Query: 174 DLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQE---NFIAMEA 230 +LQ +I E + +E K+ + ED KQ++ + Q+ N + A Sbjct: 388 ELQNQITELQKQLEENKKSYSEETEQLKQIIDDDSKQIEDLKQKLAEAQDHEGNSDSQLA 447 Query: 231 EWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXX 290 + + EKQ+L K + + L+ N +A +++ E+S L +++E+ Sbjct: 448 KLQTEKQQLDKKLVDVANALRKLKTKNDNDQATISKLNEENSSLQKQIEELKQQTANNAS 507 Query: 291 XXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNK--ELENK 348 + Q+++ ++ L+I N T+ EHL ++ + NK E+E + Sbjct: 508 YEAEI--QNLKKQLQD---------LQIQNDDIKTEN----EHLQQEMFENNKSEEIEQQ 552 Query: 349 LATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIA 408 + K +SS S + N + +Q +E L Q+ + N EI Sbjct: 553 KKQISELQKEISSKSSEIQAKNDEIENLNKEIEQIKKENQELNEELFQNNENNSNDEEIE 612 Query: 409 KLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHV 468 KL+ IQSL K++ D +S+++ K+ L + Q E ++ G Sbjct: 613 KLKTQIQSLQKEISD----LSQQNNNYKSQVEEL--KEEL-EKHQSEQDENGWGEENESE 665 Query: 469 GTNTEDVNEIAKVQEQLKQELN---DEIKDVNV---KDLIEKLKSAEEQITQLNDEIDAA 522 +E+ N + K E+LK++LN D+ ++ N ++ E LKS EQ+ + N+ + Sbjct: 666 ELKSENEN-LKKQIEELKEQLNQKEDQGQEENGWCNENETEDLKSEIEQLKKENETLKQN 724 Query: 523 NKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQ 582 N+ K +LK +Q+++ D + + +E E +++ LE EK L Sbjct: 725 NETESLKKQIEELK-EQLKQKEDQGQEENGWGEE-----NETEDYKSQISALENEKRTLN 778 Query: 583 LHLVDYDSG-RMIESDVYKKMIEMENLAET----RLKAISLLESQKFDLVQELHILQQKY 637 + D +G + ++S K +++ A K IS+ ++ + + EL ++ Sbjct: 779 KKIKDLANGLKTLKSKNEKLEQQLKENANNGNNDNSKDISVEFNETEEKITELEFENEEL 838 Query: 638 DEVEDKLADISQL---QSDQVCSEIKSVH-----LEEQIDALS----ASKKELALVIENL 685 + L++ + Q++++ SE K++ L EQ++ L ++ EL IE+L Sbjct: 839 RRNNESLSEEKKTLHKQNNKLVSENKTLSDEVSTLREQVEELEEETISTSNELRSEIEHL 898 Query: 686 KLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQS 745 + + ++ +N+ ++ N N + D + + EKIS L K EE Sbjct: 899 RSELVVREQELEQTKNNNNNVNNNENNNSNVHSD-----QSIYEEKIS--LLKQQLEELK 951 Query: 746 KIQTQFGIDAKIQERDLYIENIESELSKYKSRIC-RLEESIAVMEDRRYSLERKADQLGS 804 + Q+ + ++++ ++ ++ +L + + +L E E+ E + +L S Sbjct: 952 QSQSSNNNNEELEKENISLKKEIEDLKQENEGLQNQLFEGGETNENNNQEKEDEIHKLKS 1011 Query: 805 YLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQN 864 ++E +K ++E N ++ EIE NK+L + ++ N Sbjct: 1012 EIEELKKKLESSEQNKEEENNGWGDENTETENIDNLKSEIEELNKKLDES----IKSNDE 1067 Query: 865 LQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKK- 923 Q + +M+Q L + + +E E K+++Q+ +L L+ +++ L Q +K Sbjct: 1068 KQKKIEEMKQENEELQTQLFENN-SEEEINKFKSQVEELTQKLQESNQKNEELQSQTEKQ 1126 Query: 924 --EIEDLEI---EFNTQIESAIRD-KKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMN 977 EI+DL+ E N +++ I D K +++ +K E + L+ Q++ K E + + Sbjct: 1127 NNEIDDLKKQKEEENEKLQKEISDLKNEISQLQQKEEENGSDLQKQIEVLKQTNEKNDED 1186 Query: 978 VEELNKMNLEL-IDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQ 1036 +E+L K EL +K Q ++ Q ++EI N KQK+E I L ++ Q Sbjct: 1187 IEQLAKQIDELQTEKEKQNEEINDLKSQLQNVSEIKSENE--KQKNE-IDDLKKENEELQ 1243 Query: 1037 VSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELK 1096 + ++ E + ++ ++ E++ + K+L +S+Q+ EE E D +K Sbjct: 1244 TQLFEIGNNQEKE-----EEIHKLKSEIEELKKKLEESEQNKEE------ENIDNLKSEN 1292 Query: 1097 ETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSV 1156 ET L E+ +++ + + + ++ + E EE E Sbjct: 1293 ET-LKEEIKRLESDNEQLKKQNSELQQENKSLHQQQSKEEEENGWGEENESEELKSENES 1351 Query: 1157 LQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLST 1216 L++Q +L +L++ + + E D + QI+ L+++ LN + +L + Sbjct: 1352 LKKQIEELKEQLKQKEDQGQEENGWGDENETEDY--KSQISALENEKRTLNKKIKDLANG 1409 Query: 1217 VAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFES----KYEQLL 1272 + L+S + ++Q+ +I + ++ + E E ++ FE+ + + L Sbjct: 1410 LKTLKSK-NEKLEQQLKDINSNNSTNDNSKDISVEFNETEEKITELEFENEELRRNNESL 1468 Query: 1273 DSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKV 1332 + + Q++ NK+V+ + +L +++ E + L+E+ N+ LRSEIE + Sbjct: 1469 SEEKKTLQKQNNKLVSENK--TLSDEVSTLREQVEELEEETISTSNE---LRSEIEHLRS 1523 Query: 1333 AFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILN-----INEENAQLKKSSXX-XXX 1386 EN + +QSI + ++ +LK+ Sbjct: 1524 ELVLREQELEQTKNNNNNVNNNENNNSNVHSDQSIYEEKISLLKQQLEELKQQQQKPFDH 1583 Query: 1387 XXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEK 1446 +N + ++ +L + E +++++ ++ DE ++ ++ E +K Sbjct: 1584 EDNNDSDEINKLKKEIEDLKQENEELQNQLFEGGETNENNNQEKEDEIHKLKSEIEELKK 1643 Query: 1447 RIEDLTYEKE--------------------SELAILRLKMHENANHYETMQKESEIERVK 1486 ++E KE SE+ L K++E + + QK+ E K Sbjct: 1644 KLESSEQNKEEENNGWGDENTETENIENLKSEIEELNKKLNELSKSNDEKQKKIEELEQK 1703 Query: 1487 LIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALEN-------QEIEIVTLNDE 1539 L E N K E ++ +L + + + K+ + Q +EN +E +I + +E Sbjct: 1704 LQESQNNKDEEEENIEDLKEQLEQLRRDAITKSKQDQEEIENLKKQIEEKEADIEEITEE 1763 Query: 1540 ITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKEL 1580 + L+ + + Q+ + + Q + E +DN +N E+ Sbjct: 1764 LEQLRKDSITKAKQDQEEIEKLQNEIQKQKEIIDN-LNAEI 1803 Score = 161 bits (392), Expect = 1e-37 Identities = 282/1405 (20%), Positives = 586/1405 (41%), Gaps = 142/1405 (10%) Query: 212 EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271 E+ K+++ ++N W DE + E+ D S +EE NK L+ + + + E Sbjct: 1014 EELKKKLESSEQNKEEENNGWGDENT----ETENIDNLKSEIEELNKKLDES-IKSNDEK 1068 Query: 272 SKLAQELEQXXXXXXXXXXXXXXLAK-QSIEPSCEEKTE-IEEKGSLEIANMTELTKKIE 329 K +E++Q + + EE T+ ++E ++ K+ Sbjct: 1069 QKKIEEMKQENEELQTQLFENNSEEEINKFKSQVEELTQKLQESNQKNEELQSQTEKQNN 1128 Query: 330 LLEHLNCQIRQTNKELENKLATMGTE-SKAVSSPSKKGSPLISR-KSGRNTASKMKSPWS 387 ++ L Q + N++L+ +++ + E S+ + GS L + + + T K Sbjct: 1129 EIDDLKKQKEEENEKLQKEISDLKNEISQLQQKEEENGSDLQKQIEVLKQTNEKNDEDIE 1188 Query: 388 QLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDT 447 QL+ + T+K+ EI L+ +Q++++ + SE + + Sbjct: 1189 QLAKQIDELQTEKEKQNEEINDLKSQLQNVSE-------IKSENEKQKNEIDDLKKENEE 1241 Query: 448 LIAQLQLEHQQHMEGPSLIH-VGTNTEDVNEIAKVQEQLKQELN-DEIKDVN--VKDLIE 503 L QL E + E IH + + E++ + + EQ K+E N D +K N +K+ I+ Sbjct: 1242 LQTQL-FEIGNNQEKEEEIHKLKSEIEELKKKLEESEQNKEEENIDNLKSENETLKEEIK 1300 Query: 504 KLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEE 563 +L+S EQ+ + N E+ NK++ + +S + + ++ + ++ N+ + + EE Sbjct: 1301 RLESDNEQLKKQNSELQQENKSLHQQQSKEEEENGWGEE--NESEELKSENESLKKQIEE 1358 Query: 564 L-HHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIE-MENLAETRLKAISLLES 621 L L QK + +EE G G E++ YK I +EN T K I Sbjct: 1359 LKEQLKQKEDQGQEENG----------WGDENETEDYKSQISALENEKRTLNKKIK---- 1404 Query: 622 QKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALV 681 DL L L+ K +++E +L DI+ S S+ SV E + ++ EL Sbjct: 1405 ---DLANGLKTLKSKNEKLEQQLKDINSNNSTNDNSKDISVEFNETEEKIT----ELEFE 1457 Query: 682 IENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKIS---ELLAK 738 E L+ + E L K L+ ++++ + E L +++E++ E IS EL ++ Sbjct: 1458 NEELRRNNESLSEEKKTLQKQNNKLVSENKTLSDEVSTLREQVEELEEETISTSNELRSE 1517 Query: 739 INH-------EEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDR 791 I H EQ QT+ + + + N+ S+ S Y+ +I L++ + ++ + Sbjct: 1518 IEHLRSELVLREQELEQTKNN-NNNVNNNENNNSNVHSDQSIYEEKISLLKQQLEELKQQ 1576 Query: 792 RYS-LERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAV--------LMDHDRVVEKQLL 842 + + + + + + +K + + +EL N+L + + + K Sbjct: 1577 QQKPFDHEDNNDSDEINKLKKEIEDLKQENEELQNQLFEGGETNENNNQEKEDEIHKLKS 1636 Query: 843 EIEHENKELQKKNQILLEENQNLQISLSDMQ--QHYNALVEKANR--TDLAESESTKYQT 898 EIE K+L+ Q EEN ++ + ++ + +E+ N+ +L++S K Q Sbjct: 1637 EIEELKKKLESSEQNKEEENNGWGDENTETENIENLKSEIEELNKKLNELSKSNDEK-QK 1695 Query: 899 QLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVT 958 ++ +LE L+ E Q ++++ IEDL+ + AI K E+ E + + Sbjct: 1696 KIEELEQKLQ----ESQNNKDEEEENIEDLKEQLEQLRRDAITKSKQDQEEIENLKKQIE 1751 Query: 959 QLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALL 1018 + EA ++E +E L + K + E I+K + Q Q ++ I+ +N L Sbjct: 1752 EKEADIEEITEELEQLRKDSITKAKQDQEEIEKLQNEIQKQ-----KEIIDNLNAEIDEL 1806 Query: 1019 KQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLL----DS 1074 +K+ E L ++ + + ++++ + ++ N++ E++ + + D+ Sbjct: 1807 GEKEAEHEDLKDELQQLRKDSLQKAKIDQAEIDRLNAEVSNLKFELENGKENIWGDDDDN 1866 Query: 1075 KQHNEELQILVR----EQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDX 1130 ++H E L ++ E +D+ E+++ + TE + ++ D A + Sbjct: 1867 EKHKETLTEIIEKLKSEIEDKNSEIEKLEEEISQFEDPTEVKQENKKLKEELDQALRQNA 1926 Query: 1131 XXXXXXXXXXXLKVQEEEEF-IQERSVLQEQSAKLNTELQECYTKIIQLE-TLNTELTGH 1188 L+ Q ++ E L+++ + E Q+ + + L+ LN + G Sbjct: 1927 ELGNVNEENNKLREQLKQSIDTNELKTLEKKLKEKEEENQKLHDDLNTLQFELNNSIAGL 1986 Query: 1189 DVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQR-- 1246 +NQ + +++ ++E+L EN L +EL + +++ F +++L +++ QR Sbjct: 1987 PKINQSESMEIRDEVERLANENKKL----SELTKKLE---EEKNFLVSQL--ENVVQRND 2037 Query: 1247 -EADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEH 1305 E + Q E EL+++L E E+LL + +EQ + ++ D E Sbjct: 2038 YEKELQNVE-ELKLKLKKAEKDNEELLQQIDE----------LVEQNETENHEKSDAESE 2086 Query: 1306 LRNLQEKYA---DVINQIEILRSEIED--EKVAFXXXXXXXXXXXXXXXXDLRTENQSYK 1360 L++L+ + A D + ++LR E+++ +K+ EN Sbjct: 2087 LKSLKAELAKLKDSEKEYQVLREEVDELTQKIEESETINKELKTIIDQNDTSAAENMYKA 2146 Query: 1361 QMQEQSIL--NINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQ 1418 Q E L ++ +N LKK S + A + +LT S + + Sbjct: 2147 QFDELKALVSDLKSQNEDLKKDSENSKQEITKLTEEKTELNANIEKLTQDNSNLSSNVEK 2206 Query: 1419 KTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQK 1478 T+E + N +F+ Q+ V E+ +A +E E + Sbjct: 2207 LTNEIS------NLKFQPTAQENV----------VPAETPVA------NEVKPSEEAVST 2244 Query: 1479 ESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLND 1538 +E E+ KL E + ++ + KQ+ + +E++ + +MQ E ++L + Sbjct: 2245 PNEDEKAKLESEKEELVKKNDEMMKQIVLMKNEIEKQNKEFAQMQERFIKANEENMSLRN 2304 Query: 1539 EITNLQNMVRASSSKIQKHVSFASD 1563 + + + K +S D Sbjct: 2305 VASKNKELETQLDQKTANVLSLRKD 2329 Score = 98.3 bits (234), Expect = 2e-18 Identities = 183/921 (19%), Positives = 395/921 (42%), Gaps = 105/921 (11%) Query: 728 SAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAV 787 S K +++L + E Q++IQ DA I+ER+ + +EL++ +I EE + Sbjct: 28 SLSKENDILKRTQAEYQAQIQKCS--DALIEERET-TATLTNELAECDKKI---EEKEKL 81 Query: 788 MEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHE 847 +ED +E + + Q E +QE E ++ L ++ ++ Q Sbjct: 82 IEDLAKEIENMKNTTSTASQNDSGL--EEVVQEFE--QKIETLESENKTMKDQ------- 130 Query: 848 NKELQKKNQILLEENQNLQISLSDMQQHY-NALVEKANRTDLAESESTKYQTQLRDLESN 906 N ELQ++ Q E L +++QQ N E + + + Q+ L+ Sbjct: 131 NSELQQQIQQYKELTDKLSTESTELQQKMENIKSEDKSAEETLLQTISDQDIQINKLKEE 190 Query: 907 LKRI------THEHQTLIVQKKKE----IEDLEIE------FNTQIESAIRDKKVLNEKY 950 L++ + ++ QK++E I DL+ + + +I S LN+ Sbjct: 191 LEQAKLAANSSEQNTNAFAQKEQELNAQITDLKNQLAAKDSLSDEIASLKAQIAELNQNN 250 Query: 951 EKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTE--QYI 1008 K+ E QL+A+ Q+ ++ ++ N ++ L K ++L + QK Q + T Q Sbjct: 251 SKSSEENEQLKAESQKDASS-DDKNSDLSRLKKAVVQLKKQIAQKDQEINDLKTSNMQLQ 309 Query: 1009 NEINKL-NALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRV 1067 N N+ N +++ +II + I + + + ++ + + + +++E +++E + Sbjct: 310 NFNNETQNVEIEKYKSQIIEFQKIIESLKAENAKLQTENTNTVDKLQSEIEKLKQENSEL 369 Query: 1068 SKQLLDSK------QHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPM 1121 Q+ +++ + EELQ + E K+L+E K ++ + + II + + Sbjct: 370 QNQIQENEDGWNDNNNEEELQNQITELQ---KQLEENKKSYSEETEQLK-QIIDDDSKQI 425 Query: 1122 SDDANNVDXXXXXXXXXXXXL-KVQEEEEFIQERSV-LQEQSAKLNTELQECYTKIIQLE 1179 D + L K+Q E++ + ++ V + KL T+ I +L Sbjct: 426 EDLKQKLAEAQDHEGNSDSQLAKLQTEKQQLDKKLVDVANALRKLKTKNDNDQATISKLN 485 Query: 1180 TLNTEL----------TGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSI----- 1224 N+ L T ++ + +I LK +L+ L +ND++ + L+ + Sbjct: 486 EENSSLQKQIEELKQQTANNASYEAEIQNLKKQLQDLQIQNDDIKTENEHLQQEMFENNK 545 Query: 1225 SSAVDQRGFEIAELWKQHLAQREADFQKTEHE---LRVQLSAFESKYEQLLDSV-----Q 1276 S ++Q+ +I+EL K+ ++ + ++ Q E L ++ + + ++L + + Sbjct: 546 SEEIEQQKKQISELQKE-ISSKSSEIQAKNDEIENLNKEIEQIKKENQELNEELFQNNEN 604 Query: 1277 SSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDE---KVA 1333 +S EE K+ T Q+ SLQ ++ D + N + + ++ ++E +SE ++ + Sbjct: 605 NSNDEEIEKLKT--QIQSLQKEISDLSQQNNNYKSQVEELKEELEKHQSEQDENGWGEEN 662 Query: 1334 FXXXXXXXXXXXXXXXXDLRTE-NQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXX 1392 +L+ + NQ Q QE++ NE + KS Sbjct: 663 ESEELKSENENLKKQIEELKEQLNQKEDQGQEENGW-CNENETEDLKSEIEQLKKENETL 721 Query: 1393 XRVNDAEA---KVLELTHQLELKDSEIYQ--------KTHEYTITLTQRNDEFENVRQQL 1441 + N+ E+ ++ EL QL+ K+ + + +T +Y ++ +E + +++ Sbjct: 722 KQNNETESLKKQIEELKEQLKQKEDQGQEENGWGEENETEDYKSQISALENEKRTLNKKI 781 Query: 1442 VEYEKRIEDLTYEKESELAILRLKMHENANH-YETMQKESEIERVKLIEELNVKITESVS 1500 + ++ L + E L ++ ENAN+ K+ +E E KITE Sbjct: 782 KDLANGLKTLKSKNEK----LEQQLKENANNGNNDNSKDISVE----FNETEEKITELEF 833 Query: 1501 LNKQVAELNKALEEEVAKTNEMQTAL--ENQEI--EIVTLNDEITNLQNMVRASSSKIQK 1556 N+++ N++L EE ++ L EN+ + E+ TL +++ L+ ++S++++ Sbjct: 834 ENEELRRNNESLSEEKKTLHKQNNKLVSENKTLSDEVSTLREQVEELEEETISTSNELRS 893 Query: 1557 HVSFASDTKQGRDEQLDNTMN 1577 + R+++L+ T N Sbjct: 894 EIEHLRSELVVREQELEQTKN 914 Score = 85.8 bits (203), Expect = 9e-15 Identities = 113/577 (19%), Positives = 232/577 (40%), Gaps = 28/577 (4%) Query: 1011 INKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQ 1070 ++K N +LK+ E A QK ++A + + ++LA+ K+E E+ ++ ++K+ Sbjct: 29 LSKENDILKRTQAEYQAQIQKCSDALIEERETTATLTNELAECDKKIEEKEKLIEDLAKE 88 Query: 1071 LLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDX 1130 + + K Q+D L+E FE I E S + M D + + Sbjct: 89 IENMKNTTS-----TASQND--SGLEEVVQEFEQKIETLE-----SENKTMKDQNSELQQ 136 Query: 1131 XXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDV 1190 L + E + ++ E + T LQ + IQ+ L EL + Sbjct: 137 QIQQYKELTDKLSTESTELQQKMENIKSEDKSAEETLLQTISDQDIQINKLKEELEQAKL 196 Query: 1191 V---NQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQRE 1247 +++ N K ++LN + +L + +A + S+S + +IAEL + + E Sbjct: 197 AANSSEQNTNAFAQKEQELNAQITDLKNQLA-AKDSLSDEIASLKAQIAELNQNNSKSSE 255 Query: 1248 ADFQ-KTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHL 1306 + Q K E + S +L +V ++ K + + + +LQ+ Sbjct: 256 ENEQLKAESQKDASSDDKNSDLSRLKKAVVQLKKQIAQKDQEINDLKTSNMQLQNFNNET 315 Query: 1307 RNLQ-EKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQ 1365 +N++ EKY I + + + ++ E L+ EN ++Q Q Sbjct: 316 QNVEIEKYKSQIIEFQKIIESLKAENAKLQTENTNTVDKLQSEIEKLKQEN---SELQNQ 372 Query: 1366 SILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTI 1425 + NE+ + ++ + + E T QL+ + ++ + Sbjct: 373 --IQENEDGWNDNNNEEELQNQITELQKQLEENKKSYSEETEQLKQIIDDDSKQIEDLKQ 430 Query: 1426 TLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQK--ESEIE 1483 L + D N QL + + + L + LR +N N T+ K E Sbjct: 431 KLAEAQDHEGNSDSQLAKLQTEKQQLDKKLVDVANALRKLKTKNDNDQATISKLNEENSS 490 Query: 1484 RVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNL 1543 K IEEL + + S ++ L K L++ + ++++T E+ + E+ N++ + Sbjct: 491 LQKQIEELKQQTANNASYEAEIQNLKKQLQDLQIQNDDIKTENEHLQQEMFE-NNKSEEI 549 Query: 1544 QNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKEL 1580 + + S++QK +S S Q ++++++N +NKE+ Sbjct: 550 EQQ-KKQISELQKEISSKSSEIQAKNDEIEN-LNKEI 584 >UniRef50_Q234R7 Cluster: Viral A-type inclusion protein repeat containing protein; n=2; Eukaryota|Rep: Viral A-type inclusion protein repeat containing protein - Tetrahymena thermophila SB210 Length = 4039 Score = 188 bits (457), Expect = 1e-45 Identities = 289/1459 (19%), Positives = 637/1459 (43%), Gaps = 127/1459 (8%) Query: 144 VTHLSNTIKEKDNALSVLQVKMKIMETTILDLQE--KI--NEKDQII-EAKNKATTXXXX 198 + L+ I EK+ +S L K + + I ++E K+ ++KD +I + KN+ Sbjct: 2533 IISLNQKISEKEAQISQLNFKCESLNCQIEQIKELKKLVESQKDDVIADLKNRLQEQLTD 2592 Query: 199 XXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESK-DVRISSLEEAN 257 E+ K +Q+N ++++ + K ++ ++E++ + L E Sbjct: 2593 LTSQNKNDKALKNEEEKN--IALQQNIEDLKSQVDNYKIKV-SELETQIKYELQMLNEKK 2649 Query: 258 KLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLE 317 + LE A E+ +L +++E+ + K E + ++ EI+ + Sbjct: 2650 QDLENANKRFREENKQLKEQIEKLNSNYQENKVANDSVTKLQTELN-QKINEIDHLKE-Q 2707 Query: 318 IANMTEL--TKKIELLEHLNCQIRQTNKELENKLATMGTESKA----VSSPSKKGSPLIS 371 I N + T+K+EL N Q+++T + E K+ + +S+ + + +K S +I Sbjct: 2708 IINQDKQFKTEKMELENRFN-QMKETLTKNEQKMKQLEEKSEIELQKLQAKKQKISTIIE 2766 Query: 372 R---KSGRNTASKMKSPWSQLSSETLNQDTDKKIN-KNEIAKLEMVIQSLNKDLVDKEYV 427 KS K + Q + ++ +K IN KNE+++ + L ++ Sbjct: 2767 EAKAKSDEIILLKNEQIKIQAQYDNISNQLEKSINEKNELSQKIQNMSQQRDSLEEQRNQ 2826 Query: 428 ISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQH----MEGPSLIHVGT-NTEDVNEIAKVQ 482 I E+ K L+ Q +LE + ++ S + + N VNE + Q Sbjct: 2827 IKEQFNTLKETLKHTESKLELV-QKELEQAKQEKTSIQAQSSEKIKSLNDSMVNEFSS-Q 2884 Query: 483 EQLKQELNDEIKDVNV--KDLIEKLKSAEE--QITQLNDEIDAANKNMIKVKSNHKLKLK 538 Q+ ++L D+I ++ + EK++ E +I + +D+I++ N ++ + + + + Sbjct: 2885 NQIIEQLKDQISRLSQIQQKQQEKIQEVENISEIKKKSDQIESNNNSLQQQIFRMQEEKE 2944 Query: 539 QMQ-KTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLV-DYDSGRMIES 596 Q+ +T D K+ + K + L EE + + LEE+ + QL L + D ++S Sbjct: 2945 QITLQTSDLNLKLEEQRKLYLNLVEENGKNKETIRSLEEKLSSEQLRLQKEVDQHEQLKS 3004 Query: 597 DVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVC 656 + + +EN A+ + K + +L K + +EL Q++Y+ K Q Q++Q Sbjct: 3005 RYEQIQLNLEN-AKIQNKELEILNQSKENRTKEL---QEQYENSMRKYE--KQKQNNQEL 3058 Query: 657 SEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQE 716 ++K+V E+ ++ K+ + ++L+K E DK I+NK ++E Sbjct: 3059 -KLKTVEQEKYLNQAQIQIKDFEEQLRQMQLNKRS--------EEDKILILNKQIEELKE 3109 Query: 717 NMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKS 776 + K + E +++ + +++ E S + G +I + D YI E E+ Sbjct: 3110 EI----KQLILKNEVLNQKITSVSNLENSDHSQKIGELQQILKND-YISKQEYEV----- 3159 Query: 777 RICR-LEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDR 835 IC+ LE+ D ER++ +Y Q +K ++ Q+ + + + D++ Sbjct: 3160 -ICKKLEQKNKDCLDLEQRFERESQ---NYEQNLKKIEEKFQKQQQLTEQKYSEMQDNNE 3215 Query: 836 VVEKQLLE-IEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESEST 894 + K+ LE ++ ++++L ++ Q+ EE + +Q+ +N L EK Sbjct: 3216 IQHKKSLEQLKEKHEKLMQQQQVSFEEEKE------GLQKKFNLLKEK------------ 3257 Query: 895 KYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNI 954 L + E + ++ E Q +I Q K +I+ E+N Q + + K L E ++N+ Sbjct: 3258 -----LTNSEDQISQVEQEKQKIISQNKSKIQ----EYNEQQLAQEQIIKNLQESIKQNL 3308 Query: 955 EYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKL 1014 + +T+ E +++ + ++N +++ K ++ + K +++ Q ++ ++ IN +N+ Sbjct: 3309 QKMTEQEELIKKQQKQVKNSEEIIDQ-QKQQIDELQKSLKQTQAENEKQMQEQINNLNQK 3367 Query: 1015 NALLKQK----DEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQ 1070 ++ + + +++I + QK+ S+V+DYE ++ +L+ + E+ +Q Sbjct: 3368 ISIKESECTNLQQQLIQIEQKMKEEN---QSLVADYEKQIKTLKDELDLITREVTAQKEQ 3424 Query: 1071 LLDSKQH----NEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDAN 1126 ++ +L L +E ++I ++++ K ++ I +T I +S++ Sbjct: 3425 EKSQQEQINKLESQLNELTKENQEKIAQIEQIK-DEDLKIIQTLKNEIQELESSISNNKQ 3483 Query: 1127 NVDXXXXXXXXXXXXLKVQEEEEF---IQERSVLQEQSAKLNTELQECYTKIIQLETLNT 1183 ++ LK E++ E LQE A L +++E + + E +N Sbjct: 3484 QIETSTNQYQSELTKLKEDSEQKLELKSAEIQKLQENIAILTKQIEEEQKQ--KTELINQ 3541 Query: 1184 ELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAEL--RSSISSAVDQRGFEIAELWKQ 1241 + +E N S Q+ + L+ + EL + I S +++R E +EL + Sbjct: 3542 HQSEIQNKEKELANFQNSNSIQIKNLEEQLIQSQKELDEKKQILSQLEERQKE-SELSIK 3600 Query: 1242 HLAQREADFQK-TEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQN-KL 1299 L ++ + Q+ H Q + E K LL +Q ++ ++ M+ L L Sbjct: 3601 QLQEKLSQKQEEVVHLQTTQNATKEEKISILLSQIQELEKQLSDSKSEMKNKNQLSEASL 3660 Query: 1300 QDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSY 1359 + +E + L++KY+++ +L SE++ ++ E + Sbjct: 3661 NEAKEKITILEQKYSNLQKNYSLLESELKQALEKSKKEKDELIQTHQQELSQVQKEFITL 3720 Query: 1360 KQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQK 1419 E++ +++ E+++Q+K+ S ++ + K + QL+LK+SEI Q Sbjct: 3721 NSQIEKNKIDMIEKDSQIKRISIEHDETQK----QLESLKQKYQQSLEQLQLKESEITQL 3776 Query: 1420 THEYTITLTQRNDEFENVRQ----QLVEYEKRIEDLTYEKESELAILR---LKMHENANH 1472 + + + + E +++ Q+ + K ++ + +SEL K+ + Sbjct: 3777 KKQMQLDKYEALSQIEQLKREQNNQIDQINKEYQEKIQKLQSELQKGNDEAQKLRQQIES 3836 Query: 1473 YETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIE 1532 + + + S E LI+++ + E+V N+ +AEL L + + NE+ + E + Sbjct: 3837 LQAISQGSSNEMQNLIQKMKEQQEENVKSNQSIAELQSQLVKSNLQANELNQKISKLESK 3896 Query: 1533 IVTLNDEITNLQNMVRASS 1551 + + + I L+ SS Sbjct: 3897 LQSTENFIDALKKQENQSS 3915 Score = 163 bits (395), Expect = 5e-38 Identities = 264/1450 (18%), Positives = 647/1450 (44%), Gaps = 141/1450 (9%) Query: 162 QVKMKIMETTILDL-QEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXE------DT 214 Q +++ + + IL + QEK + QI ++KN+ + + Sbjct: 2122 QTQIESLNSKILQIEQEKTDAIKQIEQSKNQEIASNLLMTNQKISNLEEQFKQKLADFEN 2181 Query: 215 KQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEA-NKLLEAARFEISLEHSK 273 Q K Q+ I E + +++ D+E ++ +I LE+A KL+E + + + Sbjct: 2182 IQNSQKKQKKKIQKEESYLNQESG--NDLEDQERQIKQLEDAYQKLMEQHERNQTEQQQE 2239 Query: 274 LAQELEQXXXXXXXXXXXXXXLAKQSIEPSC---EEKTEIEEKGSLEIANMTELTKKIEL 330 + ++ + L ++ E S E + + E+ E+ E+ I+ Sbjct: 2240 MKRQYDNIEEQIRENLQKQMQLMQEKYERSMVIYENQIKEEQSKYRELRQSHEIA--IKN 2297 Query: 331 LEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLS 390 L L+ ++T + N+ + + K L + + S++ Sbjct: 2298 LNDLHFSQQKTVLDQSNEKVDL------LKQQLSKYEELFQKSVEEQKQQFERISQSEIQ 2351 Query: 391 SETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIA 450 +N +++ K+ +I L+ + + + D E ++ +K+ K + Sbjct: 2352 KGIINVESEYKL---QIQSLQDKLSHAMEKMQDCEQLLKKKEEQEKNLIEEYDKKIVQVL 2408 Query: 451 QLQLEH-QQHMEGPSLIHVGTNTEDVN---EIAKVQEQLKQELNDEIKDVNVKDLIEK-L 505 Q + Q+ + S ++ ++ N EI ++QE +KQ+ +I++ N+KDLI++ Sbjct: 2409 QNDIACLQESLINQSKQNMKELSQIQNAQKEIGEIQETIKQQ---KIQENNLKDLIQQHF 2465 Query: 506 KSAEEQITQLNDEIDAANKNMIKVKSN--HK--LKLKQMQKTIDN----FSKVSDSNKEI 557 + + + + DE + ++ K N H+ L L + + ++N S+ ++ N+++ Sbjct: 2466 SNIQTSLQAVKDESIKNQSHQLQEKCNEIHQKILSLLESKHLLENKHAVASEEAEENQKL 2525 Query: 558 VRLTEELH-HLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAI 616 + ++E+ L+QK++E E + L + ++E + E + Sbjct: 2526 AKESKEMIISLNQKISEKEAQISQLNFKCESLNC-------------QIEQIKELK---- 2568 Query: 617 SLLESQKFDLVQELHILQQKYDEVEDKLADI-SQLQSDQVCS--EIKSVHLEEQIDALSA 673 L+ESQK D++ +L + ++++L D+ SQ ++D+ E K++ L++ I+ L + Sbjct: 2569 KLVESQKDDVIADLK------NRLQEQLTDLTSQNKNDKALKNEEEKNIALQQNIEDLKS 2622 Query: 674 SKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKIS 733 + + L+ Q+ ++ L K+D+ N + + +EN L +++EK+++ Sbjct: 2623 QVDNYKIKVSELET---QIKYELQMLNEKKQDLENANKRFREENKQLKEQIEKLNSNYQE 2679 Query: 734 ELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKS-------RICRLEESIA 786 K+ ++ +K+QT+ ++ KI E D E I ++ ++K+ R +++E++ Sbjct: 2680 N---KVANDSVTKLQTE--LNQKINEIDHLKEQIINQDKQFKTEKMELENRFNQMKETLT 2734 Query: 787 VMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRV-VEKQLLEIE 845 E + LE K++ LQ K++ S I+E + + +L+ ++++ ++ Q I Sbjct: 2735 KNEQKMKQLEEKSEIELQKLQAKKQKISTI-IEEAKAKSDEIILLKNEQIKIQAQYDNIS 2793 Query: 846 HE-NKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKY-QTQLRDL 903 ++ K + +KN+ L ++ QN+ +++ N + E+ N E+ K+ +++L + Sbjct: 2794 NQLEKSINEKNE-LSQKIQNMSQQRDSLEEQRNQIKEQFNTL----KETLKHTESKLELV 2848 Query: 904 ESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQ 963 + L++ E ++ Q ++I+ L N + + + + E+ + I ++Q++ + Sbjct: 2849 QKELEQAKQEKTSIQAQSSEKIKSL----NDSMVNEFSSQNQIIEQLKDQISRLSQIQQK 2904 Query: 964 LQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDE 1023 QE +EN++ ++ ++ +E + +Q+Q + + EQ + + LN L+++ + Sbjct: 2905 QQEKIQEVENISEIKKKSDQ--IESNNNSLQQQIFRMQEEKEQITLQTSDLNLKLEEQRK 2962 Query: 1024 ---EIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEE 1080 ++ N K S +S + +L + + E ++ +++ L ++K N+E Sbjct: 2963 LYLNLVEENGKNKETIRSLEEKLSSEQLRLQKEVDQHEQLKSRYEQIQLNLENAKIQNKE 3022 Query: 1081 LQILVREQDDQIKELKE----TKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXX 1136 L+IL + ++++ KEL+E + +E + + + + + + + Sbjct: 3023 LEILNQSKENRTKELQEQYENSMRKYEKQKQNNQELKLKTVEQEKYLNQAQIQIKDFEEQ 3082 Query: 1137 XXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQI 1196 L + EE+ I +L +Q +L E+++ I++ E LN ++T + Sbjct: 3083 LRQMQLNKRSEEDKIL---ILNKQIEELKEEIKQL---ILKNEVLNQKITSVSNLENSDH 3136 Query: 1197 NQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHE 1256 +Q +L+Q+ +ND + E+ ++ ++ + +++ E + +K E + Sbjct: 3137 SQKIGELQQI-LKNDYISKQEYEVICKKLEQKNKDCLDLEQRFERESQNYEQNLKKIEEK 3195 Query: 1257 LRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKY--- 1313 + Q E KY ++ D+ + ++ ++ + Q ++ +EE LQ+K+ Sbjct: 3196 FQKQQQLTEQKYSEMQDNNEIQHKKSLEQLKEKHEKLMQQQQVSFEEEK-EGLQKKFNLL 3254 Query: 1314 ADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQE---QSILNI 1370 + + E S++E EK + Q K +QE Q++ + Sbjct: 3255 KEKLTNSEDQISQVEQEKQKIISQNKSKIQEYNEQQL---AQEQIIKNLQESIKQNLQKM 3311 Query: 1371 NEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQR 1430 E+ +KK ++ + ++ EL L+ +E ++ E L Q+ Sbjct: 3312 TEQEELIKKQQKQVKNSEEI----IDQQKQQIDELQKSLKQTQAENEKQMQEQINNLNQK 3367 Query: 1431 ----NDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVK 1486 E N++QQL++ E+++++ E +S +A + +T++ E ++ + Sbjct: 3368 ISIKESECTNLQQQLIQIEQKMKE---ENQSLVA-------DYEKQIKTLKDELDLITRE 3417 Query: 1487 LIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIV-TLNDEITNLQN 1545 + + + ++ +NK ++LN+ +E K +++ +++++++I+ TL +EI L++ Sbjct: 3418 VTAQKEQEKSQQEQINKLESQLNELTKENQEKIAQIEQ-IKDEDLKIIQTLKNEIQELES 3476 Query: 1546 MVRASSSKIQ 1555 + + +I+ Sbjct: 3477 SISNNKQQIE 3486 Score = 160 bits (389), Expect = 3e-37 Identities = 293/1460 (20%), Positives = 632/1460 (43%), Gaps = 137/1460 (9%) Query: 149 NTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXX 208 N IKE+ + L+ +I + DL +++ +++ N+ Sbjct: 2275 NQIKEEQSKYRELRQSHEIAIKNLNDLH--FSQQKTVLDQSNEKVDLLKQQLSKYEELFQ 2332 Query: 209 XXXEDTKQQM-----TKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAA 263 E+ KQQ +++Q+ I +E+E+K + Q L + ++ E+ K E Sbjct: 2333 KSVEEQKQQFERISQSEIQKGIINVESEYKLQIQSLQDKLSHAMEKMQDCEQLLKKKEEQ 2392 Query: 264 RFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTE 323 + E+ K ++ Q L QS + + +E ++I+ EI + E Sbjct: 2393 EKNLIEEYDKKIVQVLQNDIACLQES-----LINQS-KQNMKELSQIQN-AQKEIGEIQE 2445 Query: 324 LTKKIELLEH-LNCQIRQTNKELENKLATMGTES-KAVSSPSKKGSPLISRKSGRNTASK 381 K+ ++ E+ L I+Q ++ L + ES K S ++ I +K SK Sbjct: 2446 TIKQQKIQENNLKDLIQQHFSNIQTSLQAVKDESIKNQSHQLQEKCNEIHQKILSLLESK 2505 Query: 382 --MKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXX 439 +++ + S E + ++K+ K EM+I SLN+ + +KE IS+ + Sbjct: 2506 HLLENKHAVASEEA---EENQKLAKES---KEMII-SLNQKISEKEAQISQLNFKC---- 2554 Query: 440 XXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVK 499 ++L Q++ Q E L+ + +DV IA ++ +L+++L D + N Sbjct: 2555 ------ESLNCQIE----QIKELKKLVE--SQKDDV--IADLKNRLQEQLTD-LTSQNKN 2599 Query: 500 DLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTID-NFSKVSDSNKEIV 558 D + LK+ EE+ L I+ + N+K+K+ +++ I +++ +++ Sbjct: 2600 D--KALKNEEEKNIALQQNIEDLKSQV----DNYKIKVSELETQIKYELQMLNEKKQDLE 2653 Query: 559 RLTEELHHLSQKVAE-LEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAIS 617 + ++++ E +E+ N Q + V DS +++++ +K+ E+++L E + Sbjct: 2654 NANKRFREENKQLKEQIEKLNSNYQENKVANDSVTKLQTELNQKINEIDHLKEQIINQDK 2713 Query: 618 LLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKE 677 +++K +L + +++ + E K+ + + SEI ++ L A K++ Sbjct: 2714 QFKTEKMELENRFNQMKETLTKNEQKMKQLEEK------SEI-------ELQKLQAKKQK 2760 Query: 678 LALVIENLKLDKEQLYGTIKD---LENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISE 734 ++ +IE K +++ + ++ ++I N+L+ I E +L+ K++ MS ++ S Sbjct: 2761 ISTIIEEAKAKSDEIILLKNEQIKIQAQYDNISNQLEKSINEKNELSQKIQNMSQQRDSL 2820 Query: 735 LLAKINHEEQSKIQTQFG-IDAKIQERDLYIENIESELSKYKSRICRLE----ESIAVME 789 E++++I+ QF + ++ + +E ++ EL + K ++ E I + Sbjct: 2821 ------EEQRNQIKEQFNTLKETLKHTESKLELVQKELEQAKQEKTSIQAQSSEKIKSLN 2874 Query: 790 DRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENK 849 D + +Q+ L+++ S+ ++ E + + + + ++K+ +IE N Sbjct: 2875 DSMVNEFSSQNQIIEQLKDQISRLSQIQQKQQEKIQEVENISE----IKKKSDQIESNNN 2930 Query: 850 ELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDL-AESESTKYQTQLRDLESNLK 908 LQ++ + EE + + + SD+ N +E+ + L E+ K + +R LE L Sbjct: 2931 SLQQQIFRMQEEKEQITLQTSDL----NLKLEEQRKLYLNLVEENGKNKETIRSLEEKLS 2986 Query: 909 RITHEHQTLIVQK---KKEIEDLEIEF-NTQIESAIRDKKVLNEKYEKNI-EYVTQLEAQ 963 Q + Q K E +++ N +I++ ++ ++LN+ E E Q E Sbjct: 2987 SEQLRLQKEVDQHEQLKSRYEQIQLNLENAKIQN--KELEILNQSKENRTKELQEQYENS 3044 Query: 964 LQEY---KNNIENLNMNVEE----LNKMNLELIDKHVQKQQTQSPDYTEQ-YINEINKLN 1015 +++Y K N + L + E LN+ +++ D Q +Q Q +E+ I +NK Sbjct: 3045 MRKYEKQKQNNQELKLKTVEQEKYLNQAQIQIKDFEEQLRQMQLNKRSEEDKILILNKQI 3104 Query: 1016 ALLKQKDEEIIALNQKINNAQVSYMSMV-SDYESKLAQFTTKLEN---MEEEMQRVSKQL 1071 LK++ +++I N+ +N S ++ SD+ K+ + L+N ++E + + K+L Sbjct: 3105 EELKEEIKQLILKNEVLNQKITSVSNLENSDHSQKIGELQQILKNDYISKQEYEVICKKL 3164 Query: 1072 LDSKQHNEEL-QILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDX 1130 + +L Q RE + + LK+ + F+ TE M D+ N + Sbjct: 3165 EQKNKDCLDLEQRFERESQNYEQNLKKIEEKFQKQQQLTE-----QKYSEMQDN-NEIQH 3218 Query: 1131 XXXXXXXXXXXLKVQEEEE--FIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGH 1188 K+ ++++ F +E+ LQ++ L +L +I Q+E ++ Sbjct: 3219 KKSLEQLKEKHEKLMQQQQVSFEEEKEGLQKKFNLLKEKLTNSEDQISQVEQEKQKIISQ 3278 Query: 1189 DVVNQEQINQLKSKLEQL--NTEND--NLLSTVAELRSSISSAVDQ--RGFEIAELWKQH 1242 + ++ N+ + EQ+ N + L + E I Q EI + KQ Sbjct: 3279 NKSKIQEYNEQQLAQEQIIKNLQESIKQNLQKMTEQEELIKKQQKQVKNSEEIIDQQKQQ 3338 Query: 1243 LAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNK--LQ 1300 + + + ++T+ E Q+ + Q + +S +++ +EQ +N+ + Sbjct: 3339 IDELQKSLKQTQAENEKQMQEQINNLNQKISIKESECTNLQQQLIQIEQKMKEENQSLVA 3398 Query: 1301 DKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYK 1360 D E+ ++ L+++ D+I + + E E + + + + K Sbjct: 3399 DYEKQIKTLKDEL-DLITREVTAQKEQEKSQQEQINKLESQLNELTKENQEKIAQIEQIK 3457 Query: 1361 QMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQ-LELKDSEIYQK 1419 + I + E +L+ S + K+ E + Q LELK +EI QK Sbjct: 3458 DEDLKIIQTLKNEIQELESSISNNKQQIETSTNQYQSELTKLKEDSEQKLELKSAEI-QK 3516 Query: 1420 THEYTITLTQRNDEFENVRQQLV-EYEKRIEDLTYEKESELAILRLKMHENANHYET--M 1476 E LT++ +E + + +L+ +++ I++ KE ELA + + E + Sbjct: 3517 LQENIAILTKQIEEEQKQKTELINQHQSEIQN----KEKELANFQNSNSIQIKNLEEQLI 3572 Query: 1477 QKESEI-ERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVT 1535 Q + E+ E+ +++ +L + ES KQ+ E +EEV Q A + ++I I Sbjct: 3573 QSQKELDEKKQILSQLEERQKESELSIKQLQEKLSQKQEEVVHLQTTQNATKEEKISI-- 3630 Query: 1536 LNDEITNLQNMVRASSSKIQ 1555 L +I L+ + S S+++ Sbjct: 3631 LLSQIQELEKQLSDSKSEMK 3650 Score = 145 bits (351), Expect = 1e-32 Identities = 271/1435 (18%), Positives = 619/1435 (43%), Gaps = 118/1435 (8%) Query: 176 QEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDE 235 Q +++EK +++++ + +++ K+ E + + E+K++ Sbjct: 1535 QNELSEKQKLLDSLSDQLKIDQELLMKERQKLQEETVQFEEKQNKLTEEILKQQQEYKEK 1594 Query: 236 KQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXL 295 + L+D + + L E + ++SL S + ++ EQ L Sbjct: 1595 YDKYLQDFQEYQNLMKQLSIQKVAQEELQNQLSLRSSLIKEQQEQLEKHLLNLTEQQQQL 1654 Query: 296 AKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTE 355 K I ++K E+K L + K+ E ++ QI+Q +E++ + E Sbjct: 1655 -KDIIVQFDKKK---EDKNQLIEYFQAQCEKQEEEIK----QIKQKYEEIQKLSQDINLE 1706 Query: 356 SKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQ 415 + V + ++ +N ++S + SET N NK E+ L + +Q Sbjct: 1707 KEIVKREHAQ------CQNSQNQIDIVRSDYQNKISETNNS------NKKELEALNLALQ 1754 Query: 416 SLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDV 475 N+ + +++ +I + ++ + E +Q +E + + + Sbjct: 1755 EKNERIAEQKEMIKSLNQTIKSLESKIENL-SIKSDNYDETKQKLEQKNEELILLKQQVA 1813 Query: 476 NEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKL 535 E + Q L Q LND +K ++ K+ EEQ Q +E+ +N IK +S Sbjct: 1814 QEQKEKQIFLNQ-LND-LKSIDEKNQ-NNFTKKEEQYQQKINELQLQFQNEIKTESAQIN 1870 Query: 536 KLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIE 595 KL+ +T K+ + ++ ++++ Q EE+ LQ+ L + R E Sbjct: 1871 KLRDEYQT-----KIDEMKEKYFESSQKMKEAEQISQFKEEQIKQLQISLESEQNNRKEE 1925 Query: 596 SDVYKKMIEMENLA-ETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQ 654 +K E + A + LK +++K + E H + Q + +K D QL+++ Sbjct: 1926 KQTLQKYFEEQFAAIISHLKE----DNEKLKQLHENHSVVQ----LNEKEQDFIQLKTNY 1977 Query: 655 VCSEIKSVHLEEQI-DALSASKKELALVIENLKLDKEQLYGTIKDLE-NDKEDIMNKLQN 712 E ++ L+ + + ++ K + L + NL + QL+ T L ++K+++ ++Q Sbjct: 1978 ALIEQQADILKSLMQNEIAQKKNQSQLNLSNLTV--LQLFETFIQLNASEKQNLEEEIQK 2035 Query: 713 YIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELS 772 + T+K K ++E AK + ++I K + I +E + + Sbjct: 2036 L---KISHTEKDSKYLL--LTEDFAKYKDQIATEISNLKEKSHKNDYQTELINQLEQKNA 2090 Query: 773 KYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQ-EDELVNRL-AVL 830 K K + +L+E + E++ L+ + +L Q + ++ + +Q E E + + + Sbjct: 2091 KVKQKCSQLQEKLQETENQ---LKSQIFELEKQHQTQIESLNSKILQIEQEKTDAIKQIE 2147 Query: 831 MDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAE 890 ++ + LL + L+++ + L + +N+Q S +Q E++ + Sbjct: 2148 QSKNQEIASNLLMTNQKISNLEEQFKQKLADFENIQ--NSQKKQKKKIQKEESYLNQESG 2205 Query: 891 SESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQI-ESAIRDKKVLNEK 949 ++ + Q++ LE +++ +H+ ++++E++ QI E+ + +++ EK Sbjct: 2206 NDLEDQERQIKQLEDAYQKLMEQHERNQTEQQQEMKRQYDNIEEQIRENLQKQMQLMQEK 2265 Query: 950 YEKN-IEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYI 1008 YE++ + Y Q++ + +Y+ ++ + ++ LN ++ K V Q + D +Q Sbjct: 2266 YERSMVIYENQIKEEQSKYRELRQSHEIAIKNLNDLHFSQ-QKTVLDQSNEKVDLLKQ-- 2322 Query: 1009 NEINKLNALLKQKDEEIIALNQKINNAQV--SYMSMVSDYESKLAQFTTKLENMEEEMQR 1066 +++K L ++ EE ++I+ +++ +++ S+Y+ ++ KL + E+MQ Sbjct: 2323 -QLSKYEELFQKSVEEQKQQFERISQSEIQKGIINVESEYKLQIQSLQDKLSHAMEKMQD 2381 Query: 1067 VSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDAN 1126 +QLL K+ E + L+ E D +I ++ + +I + +I+ + + M + + Sbjct: 2382 -CEQLLKKKEEQE--KNLIEEYDKKIVQV------LQNDIACLQESLINQSKQNMK-ELS 2431 Query: 1127 NVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELT 1186 + +K Q+ +E + ++Q+ + + T LQ ++ E++ + Sbjct: 2432 QIQNAQKEIGEIQETIKQQKIQE-NNLKDLIQQHFSNIQTSLQ-----AVKDESIKNQ-- 2483 Query: 1187 GHDVVNQEQINQLKSKLEQLNTENDNLLS---TVAELRSSISSAVDQRGFEIAELWKQHL 1243 H + QE+ N++ K+ L E+ +LL VA + + + + E+ Q + Sbjct: 2484 SHQL--QEKCNEIHQKILSL-LESKHLLENKHAVASEEAEENQKLAKESKEMIISLNQKI 2540 Query: 1244 AQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVT--MEQVTSLQNKLQD 1301 +++EA + + L+ + ++L V+S + + EQ+T L ++ Sbjct: 2541 SEKEAQISQLNFKCE-SLNCQIEQIKELKKLVESQKDDVIADLKNRLQEQLTDLTSQ-NK 2598 Query: 1302 KEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQ 1361 ++ L+N +EK + IE L+S++++ K+ +L+ N+ KQ Sbjct: 2599 NDKALKNEEEKNIALQQNIEDLKSQVDNYKI-------KVSELETQIKYELQMLNEK-KQ 2650 Query: 1362 MQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKV-LELTHQLELKD---SEIY 1417 E + EEN QLK+ ND+ K+ EL ++ D +I Sbjct: 2651 DLENANKRFREENKQLKEQIEKLNSNYQENKV-ANDSVTKLQTELNQKINEIDHLKEQII 2709 Query: 1418 QKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQ 1477 + ++ + + F +++ L + E++++ L + E EL L+ K + + E + Sbjct: 2710 NQDKQFKTEKMELENRFNQMKETLTKNEQKMKQLEEKSEIELQKLQAKKQKISTIIEEAK 2769 Query: 1478 KESEIERVKLIEELNVKIT---ESVS--LNKQVAELNKALEEEVAKTNEMQTALENQEIE 1532 +S + + L++ +KI +++S L K + E N+ L +++ ++ + +LE Q + Sbjct: 2770 AKS--DEIILLKNEQIKIQAQYDNISNQLEKSINEKNE-LSQKIQNMSQQRDSLEEQRNQ 2826 Query: 1533 IVTLNDEITNLQNMVRASSSK---IQKHVSFASDTKQGRDEQLDNTMNKELLDAV 1584 I ++ L+ ++ + SK +QK + A K Q + K L D++ Sbjct: 2827 I---KEQFNTLKETLKHTESKLELVQKELEQAKQEKTSIQAQSSEKI-KSLNDSM 2877 Score = 141 bits (342), Expect = 1e-31 Identities = 279/1389 (20%), Positives = 593/1389 (42%), Gaps = 122/1389 (8%) Query: 230 AEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXX 289 A++KD+ + +++ K + E LE ++ + S+L ++L++ Sbjct: 2055 AKYKDQIATEISNLKEKSHKNDYQTELINQLEQKNAKVKQKCSQLQEKLQETENQ----- 2109 Query: 290 XXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKL 349 L Q E + +T+IE S + E T I+ +E + N+E+ + L Sbjct: 2110 -----LKSQIFELEKQHQTQIESLNSKILQIEQEKTDAIKQIE------QSKNQEIASNL 2158 Query: 350 ATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDT--DKKINKNEI 407 + T K + + L ++ +N+ K K Q LNQ++ D + + +I Sbjct: 2159 --LMTNQKISNLEEQFKQKLADFENIQNSQKKQKKK-IQKEESYLNQESGNDLEDQERQI 2215 Query: 408 AKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIH 467 +LE Q L + ++ +++ ++ L Q+QL +++ E +I+ Sbjct: 2216 KQLEDAYQKLMEQH-ERNQTEQQQEMKRQYDNIEEQIRENLQKQMQLMQEKY-ERSMVIY 2273 Query: 468 VGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEI----DAAN 523 E+ ++ ++++ + + + + D++ L + E++ L ++ + Sbjct: 2274 ENQIKEEQSKYRELRQSHEIAIKN-LNDLHFSQQKTVLDQSNEKVDLLKQQLSKYEELFQ 2332 Query: 524 KNMIKVKSN-HKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEE---EKG 579 K++ + K ++ ++QK I N S+ +I L ++L H +K+ + E+ +K Sbjct: 2333 KSVEEQKQQFERISQSEIQKGIINVE--SEYKLQIQSLQDKLSHAMEKMQDCEQLLKKKE 2390 Query: 580 NLQLHLVD-YDSG--RMIESDVYKKMIEMENLAETRLKAISLLESQKFDL--VQELHILQ 634 + +L++ YD +++++D+ + N ++ +K +S +++ + ++ +QE I Q Sbjct: 2391 EQEKNLIEEYDKKIVQVLQNDIACLQESLINQSKQNMKELSQIQNAQKEIGEIQET-IKQ 2449 Query: 635 QKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYG 694 QK E + L D+ Q + + +++V +E I S +E +++ Sbjct: 2450 QKIQE--NNLKDLIQQHFSNIQTSLQAVK-DESIKNQSHQLQEKC----------NEIHQ 2496 Query: 695 TIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGID 754 I L K + NK E + KL K S E I L KI+ +E Q F Sbjct: 2497 KILSLLESKHLLENK-HAVASEEAEENQKLAKESKEMIISLNQKISEKEAQISQLNF--- 2552 Query: 755 AKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQ-KAY 813 K + + IE I+ EL K + ++ IA +++R E+ D +K K Sbjct: 2553 -KCESLNCQIEQIK-ELKKLVES--QKDDVIADLKNRLQ--EQLTDLTSQNKNDKALKNE 2606 Query: 814 SEYTIQEDELVNRLAVLMDHDRVVEKQL-LEIEHENKELQKKNQILLEENQNLQISLSDM 872 E I + + L +D+ ++ +L +I++E + L +K Q L N+ + + Sbjct: 2607 EEKNIALQQNIEDLKSQVDNYKIKVSELETQIKYELQMLNEKKQDLENANKRFREENKQL 2666 Query: 873 QQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKK-EIEDLEIE 931 ++ L +A TK QT +L + I H + +I Q K+ + E +E+E Sbjct: 2667 KEQIEKLNSNYQENKVANDSVTKLQT---ELNQKINEIDHLKEQIINQDKQFKTEKMELE 2723 Query: 932 --FNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELI 989 FN E+ ++++ + + EK+ + +L+A+ Q+ IE +E+ + E I Sbjct: 2724 NRFNQMKETLTKNEQKMKQLEEKSEIELQKLQAKKQKISTIIEEAKAKSDEIILLKNEQI 2783 Query: 990 DKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSM---VSDY 1046 +Q Q + E+ INE N+L+ ++ ++ +L ++ N + + ++ + Sbjct: 2784 --KIQAQYDNISNQLEKSINEKNELSQKIQNMSQQRDSLEEQRNQIKEQFNTLKETLKHT 2841 Query: 1047 ESKLAQFTTKLENMEEEMQRVSKQLLDS-KQHNEELQILVREQDDQIKELKETKLTFEMN 1105 ESKL +LE ++E + Q + K N+ + Q+ I++LK+ Sbjct: 2842 ESKLELVQKELEQAKQEKTSIQAQSSEKIKSLNDSMVNEFSSQNQIIEQLKDQISRLSQI 2901 Query: 1106 IPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXL-KVQEEEEFI----QERSVLQEQ 1160 K + I +E +S+ D + ++QEE+E I + ++ E+ Sbjct: 2902 QQKQQEKI--QEVENISEIKKKSDQIESNNNSLQQQIFRMQEEKEQITLQTSDLNLKLEE 2959 Query: 1161 SAKLNTELQECYTKIIQ-LETLNTELTGHDVVNQEQIN---QLKSKLE--QLNTENDNLL 1214 KL L E K + + +L +L+ + Q++++ QLKS+ E QLN EN + Sbjct: 2960 QRKLYLNLVEENGKNKETIRSLEEKLSSEQLRLQKEVDQHEQLKSRYEQIQLNLENAKIQ 3019 Query: 1215 STVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDS 1274 + E+ ++ + + R E+ E ++ + + E Q + EL+++ + + KY L+ Sbjct: 3020 NKELEI---LNQSKENRTKELQEQYENSMRKYEKQKQNNQ-ELKLK-TVEQEKY---LNQ 3071 Query: 1275 VQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIE--ILRSEIEDEKV 1332 Q ++ EQ+ +Q + +E+ + L ++ ++ +I+ IL++E+ ++K+ Sbjct: 3072 AQIQIKD------FEEQLRQMQLNKRSEEDKILILNKQIEELKEEIKQLILKNEVLNQKI 3125 Query: 1333 AFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSIL--NINEENAQLKKSSXXXXXXXXX 1390 +N Y QE ++ + ++N Sbjct: 3126 TSVSNLENSDHSQKIGELQQILKN-DYISKQEYEVICKKLEQKNKDCLDLEQRFERESQN 3184 Query: 1391 XXXRVNDAEAKVLELTHQLELKDSEIYQKTH-EYTITLTQRNDEFEN-VRQQLVEYEKRI 1448 + E K + E K SE+ ++ +L Q ++ E ++QQ V +E+ Sbjct: 3185 YEQNLKKIEEKFQKQQQLTEQKYSEMQDNNEIQHKKSLEQLKEKHEKLMQQQQVSFEEEK 3244 Query: 1449 EDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAEL 1508 E L +K+ L + E + E + E E+ K+I + KI E ++ Sbjct: 3245 EGL--QKKFNL------LKEKLTNSEDQISQVEQEKQKIISQNKSKIQEYNEQQLAQEQI 3296 Query: 1509 NKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGR 1568 K L+E + K N +Q E +E+ I ++ N + ++ +I + T+ Sbjct: 3297 IKNLQESI-KQN-LQKMTEQEEL-IKKQQKQVKNSEEIIDQQKQQIDELQKSLKQTQAEN 3353 Query: 1569 DEQLDNTMN 1577 ++Q+ +N Sbjct: 3354 EKQMQEQIN 3362 Score = 137 bits (331), Expect = 3e-30 Identities = 247/1264 (19%), Positives = 538/1264 (42%), Gaps = 101/1264 (7%) Query: 337 QIRQTNKELENKLATMGTESKAVSSPSKKGSPLI--SRKSGRNTASKMKSPWSQLSSETL 394 Q ++ K +N+L+ ++S K L+ R+ + + + ++L+ E L Sbjct: 1526 QCQENIKLAQNELSEKQKLLDSLSDQLKIDQELLMKERQKLQEETVQFEEKQNKLTEEIL 1585 Query: 395 NQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQ--L 452 Q + K ++ + Q+L K L ++ E + + + L Sbjct: 1586 KQQQEYKEKYDKYLQDFQEYQNLMKQLSIQKVAQEELQNQLSLRSSLIKEQQEQLEKHLL 1645 Query: 453 QLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQI 512 L QQ ++ ED N++ + + ++ +EIK + K E+I Sbjct: 1646 NLTEQQQQLKDIIVQFDKKKEDKNQLIEYFQAQCEKQEEEIKQI---------KQKYEEI 1696 Query: 513 TQLNDEIDAANKNMIKVKSNHKLKLKQMQKTI---DNFSKVSDSN----KEIVRLTEELH 565 +L+ +I+ K ++K + + + + Q Q I D +K+S++N KE+ L L Sbjct: 1697 QKLSQDINL-EKEIVK-REHAQCQNSQNQIDIVRSDYQNKISETNNSNKKELEALNLALQ 1754 Query: 566 HLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFD 625 ++++AE +E +L + + +ES + I+ +N ET+ K LE + + Sbjct: 1755 EKNERIAEQKEMIKSLNQTI------KSLESKIENLSIKSDNYDETKQK----LEQKNEE 1804 Query: 626 LVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIEN- 684 L+ + QQ E ++K ++QL + E + ++ + EL L +N Sbjct: 1805 LIL---LKQQVAQEQKEKQIFLNQLNDLKSIDEKNQNNFTKKEEQYQQKINELQLQFQNE 1861 Query: 685 LKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQ 744 +K + Q+ ++D K D M + + M +++ + E+I +L + E+ Sbjct: 1862 IKTESAQI-NKLRDEYQTKIDEMKEKYFESSQKMKEAEQISQFKEEQIKQLQISLESEQN 1920 Query: 745 SKIQTQFGIDAKIQER-DLYIENIESELSKYKS--------RICRLEESIAVMEDRRYSL 795 ++ + + + +E+ I +++ + K K ++ E+ ++ + Sbjct: 1921 NRKEEKQTLQKYFEEQFAAIISHLKEDNEKLKQLHENHSVVQLNEKEQDFIQLKTNYALI 1980 Query: 796 ERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKN 855 E++AD L S +Q + ++ Q ++ L VL + ++ E ++ +E+QK Sbjct: 1981 EQQADILKSLMQNE---IAQKKNQSQLNLSNLTVLQLFETFIQLNASEKQNLEEEIQKLK 2037 Query: 856 QILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQL-RDLES-NLK----- 908 E++ + D ++ + + + + +S YQT+L LE N K Sbjct: 2038 ISHTEKDSKYLLLTEDFAKYKDQIATEISNLK-EKSHKNDYQTELINQLEQKNAKVKQKC 2096 Query: 909 -RITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLE-AQLQE 966 ++ + Q Q K +I +LE + TQIES + K+L + EK + + Q+E ++ QE Sbjct: 2097 SQLQEKLQETENQLKSQIFELEKQHQTQIESL--NSKILQIEQEKT-DAIKQIEQSKNQE 2153 Query: 967 YKNNIENLNM---NVEELNKMNLELID--KHVQKQQTQSPDYTEQYINEINKLNALLKQK 1021 +N+ N N+EE K L + ++ QK+Q + E Y+N+ + + L+ + Sbjct: 2154 IASNLLMTNQKISNLEEQFKQKLADFENIQNSQKKQKKKIQKEESYLNQESGND--LEDQ 2211 Query: 1022 DEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEEL 1081 + +I L + ++ + ++ + + +N+EE+++ ++ + Q E Sbjct: 2212 ERQIKQLEDAYQKLMEQHERNQTEQQQEMKR---QYDNIEEQIRENLQKQMQLMQEKYER 2268 Query: 1082 QILVREQDDQIKE----LKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXX 1137 +++ E +QIKE +E + + E+ I + S + VD Sbjct: 2269 SMVIYE--NQIKEEQSKYRELRQSHEIAIKNLNDLHFSQQKTVLDQSNEKVDLLKQQLSK 2326 Query: 1138 XXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQIN 1197 + EE+ Q + Q + K ++ Y +Q+++L +L+ H + + Sbjct: 2327 YEELFQKSVEEQKQQFERISQSEIQKGIINVESEYK--LQIQSLQDKLS-HAMEKMQDCE 2383 Query: 1198 QLKSKLEQ----LNTENDNLLSTVAE--LRSSISSAVDQRGFEIAELWKQHLAQRE-ADF 1250 QL K E+ L E D + V + + S ++Q + EL + AQ+E + Sbjct: 2384 QLLKKKEEQEKNLIEEYDKKIVQVLQNDIACLQESLINQSKQNMKELSQIQNAQKEIGEI 2443 Query: 1251 QKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQ 1310 Q+T + ++Q + + +Q ++Q+S Q ++ + Q LQ K + + + +L Sbjct: 2444 QETIKQQKIQENNLKDLIQQHFSNIQTSLQAVKDESIK-NQSHQLQEKCNEIHQKILSLL 2502 Query: 1311 EKYADVINQIEILRSEIED-EKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILN 1369 E + N+ + E E+ +K+A + + ++K +S+ Sbjct: 2503 ESKHLLENKHAVASEEAEENQKLAKESKEMIISLNQKISEKEAQISQLNFKC---ESLNC 2559 Query: 1370 INEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQ 1429 E+ +LKK N + ++ +LT Q K+ + + E I L Q Sbjct: 2560 QIEQIKELKKLVESQKDDVIADLK--NRLQEQLTDLTSQN--KNDKALKNEEEKNIALQQ 2615 Query: 1430 RNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIE 1489 E+++ Q+ Y+ ++ +L + + EL +L K + N + ++E++ + + IE Sbjct: 2616 N---IEDLKSQVDNYKIKVSELETQIKYELQMLNEKKQDLENANKRFREENK-QLKEQIE 2671 Query: 1490 ELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRA 1549 +LN E+ N V +L L +++ + + ++ + NQ+ + T E+ N N ++ Sbjct: 2672 KLNSNYQENKVANDSVTKLQTELNQKINEIDHLKEQIINQDKQFKTEKMELENRFNQMKE 2731 Query: 1550 SSSK 1553 + +K Sbjct: 2732 TLTK 2735 Score = 118 bits (283), Expect = 2e-24 Identities = 215/1166 (18%), Positives = 475/1166 (40%), Gaps = 99/1166 (8%) Query: 476 NEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLN-DEIDAANKNMIKVKSNHK 534 N K +E+ + E N ++N+K ++ S Q+TQ N E D + N K SN K Sbjct: 1310 NTFVKEEEENQAE-NGNQHNLNIKCFDDEFSSNNNQMTQNNYTENDENSSNCKKFSSNQK 1368 Query: 535 LKLKQMQKTIDNFSK----VSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDS 590 M + S +S+ + EIV + + + + + E + + Sbjct: 1369 EIESDMDQPQAGSSGGKNGISNEDHEIVMMMQNCPYHQNLINNNQFENHVCKENTEQISQ 1428 Query: 591 GRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKY-----DEVEDKLA 645 + + ++ I++ L K++ L+ + E LQQ + ++ + Sbjct: 1429 YTDLVAASQQQQIQINTLMVQLQKSLKLICDLNDRNIIEKKKLQQSISSDVQNNTDNNID 1488 Query: 646 DISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVI---ENLKL------DKEQLYGTI 696 D QV I + +EE + A ++ ++ EN+KL +K++L ++ Sbjct: 1489 DDESTFYIQVRENIIEMKVEEALKKKYAEFDQIRDIVQCQENIKLAQNELSEKQKLLDSL 1548 Query: 697 KD-LENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDA 755 D L+ D+E +M + Q +E + +K K++ E + K E + K D Sbjct: 1549 SDQLKIDQELLMKERQKLQEETVQFEEKQNKLTEE-----ILKQQQEYKEK------YDK 1597 Query: 756 KIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSE 815 +Q+ Y +N+ +LS K L+ +++ + + ++ L E+Q+ + Sbjct: 1598 YLQDFQEY-QNLMKQLSIQKVAQEELQNQLSLRSSLIKEQQEQLEKHLLNLTEQQQQLKD 1656 Query: 816 YTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQH 875 +Q D+ L+++ + Q + E E K++++K + + + +Q++ + +++ Sbjct: 1657 IIVQFDKKKEDKNQLIEY---FQAQCEKQEEEIKQIKQKYEEIQKLSQDINLEKEIVKRE 1713 Query: 876 YNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQ 935 + N+ D+ S+ YQ ++ + ++ KKE+E L + + Sbjct: 1714 HAQCQNSQNQIDIVRSD---YQNKISETNNS--------------NKKELEALNLALQEK 1756 Query: 936 IESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQK 995 E K+++ + + LE++++ +N + ++L + N ELI +++ Sbjct: 1757 NERIAEQKEMIKSLNQT----IKSLESKIENLSIKSDNYDETKQKLEQKNEELI--LLKQ 1810 Query: 996 QQTQSPDYTEQYINEINKLNALLKQKDEEII----ALNQKINNAQVSYMSMVSDYESKLA 1051 Q Q + ++N++N L ++ ++ QKIN Q+ + ++ +++ A Sbjct: 1811 QVAQEQKEKQIFLNQLNDLKSIDEKNQNNFTKKEEQYQQKINELQLQFQ---NEIKTESA 1867 Query: 1052 QFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEG 1111 Q + + ++ + ++ +S Q +E + + + +++QIK+L + L E N K E Sbjct: 1868 QINKLRDEYQTKIDEMKEKYFESSQKMKEAEQISQFKEEQIKQL-QISLESEQNNRKEEK 1926 Query: 1112 MIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQEC 1171 + E LK E + + + ++ +L T Sbjct: 1927 QTLQKYFE------EQFAAIISHLKEDNEKLKQLHENHSVVQLNEKEQDFIQLKTN---- 1976 Query: 1172 YTKIIQLETLNTELTGHDVVNQEQINQLK-SKLEQLNTENDNLLSTVAELRSSISSAVDQ 1230 Y I Q + L +++ ++ +QL S L L + + A + ++ + + Sbjct: 1977 YALIEQQADILKSLMQNEIAQKKNQSQLNLSNLTVLQL-FETFIQLNASEKQNLEEEIQK 2035 Query: 1231 RGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTME 1290 E ++L E DF K + ++ ++S + K + + Q E + Sbjct: 2036 LKISHTEKDSKYLLLTE-DFAKYKDQIATEISNLKEKSHKNDYQTELINQLEQKNAKVKQ 2094 Query: 1291 QVTSLQNKLQDKEEHLRN-LQEKYADVINQIEILRSEI-EDEKVAFXXXXXXXXXXXXXX 1348 + + LQ KLQ+ E L++ + E QIE L S+I + E+ Sbjct: 2095 KCSQLQEKLQETENQLKSQIFELEKQHQTQIESLNSKILQIEQEKTDAIKQIEQSKNQEI 2154 Query: 1349 XXDLRTENQSYKQMQEQSILNI----NEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLE 1404 +L NQ ++EQ + N +N+Q K+ ND E + + Sbjct: 2155 ASNLLMTNQKISNLEEQFKQKLADFENIQNSQKKQKKKIQKEESYLNQESGNDLEDQERQ 2214 Query: 1405 LTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEK-ESELAILR 1463 + + + Q T + +++N+ +Q+ E ++ L EK E + I Sbjct: 2215 IKQLEDAYQKLMEQHERNQTEQQQEMKRQYDNIEEQIRENLQKQMQLMQEKYERSMVIYE 2274 Query: 1464 LKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEM- 1522 ++ E + Y +++ EI +K + +L+ ++ ++ Q E L+++++K E+ Sbjct: 2275 NQIKEEQSKYRELRQSHEI-AIKNLNDLH--FSQQKTVLDQSNEKVDLLKQQLSKYEELF 2331 Query: 1523 QTALENQEIEIVTLNDE-----ITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMN 1577 Q ++E Q+ + ++ I N+++ + +Q +S A + Q ++ L Sbjct: 2332 QKSVEEQKQQFERISQSEIQKGIINVESEYKLQIQSLQDKLSHAMEKMQDCEQLL---KK 2388 Query: 1578 KELLDAVPRAELDLAMYMLHQRDVRC 1603 KE + E D + + Q D+ C Sbjct: 2389 KEEQEKNLIEEYDKKIVQVLQNDIAC 2414 Score = 51.2 bits (117), Expect = 2e-04 Identities = 85/436 (19%), Positives = 182/436 (41%), Gaps = 49/436 (11%) Query: 509 EEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHH-L 567 + I Q I K + +S + KL+ +Q + + D K V ++H+ Sbjct: 377 QNNIQQSQTNIQNYAKQLKIDRSKEEQKLRDLQNELSKINTAQDQYKSEVN---DIHYKC 433 Query: 568 SQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLV 627 ++++ E E + L L ++Y R + ++ K ++ L + + L Q+F Sbjct: 434 NERINEFERDFEKLHLAFINYK--RECDQTMFDKDQLIQQLRQELSQKNDKLLQQQFQYR 491 Query: 628 QELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKL 687 Q + Q + + + + D + ++ + + V ++A+ +I N ++ Sbjct: 492 QSFYYNQYQMNLQDMAVGDNTNTNNNSISQLVSGV-------IINANNPNNPNLIHNNQI 544 Query: 688 DKEQLYGTIKDLE---NDKED----------IMNKLQNYIQENMDLTDKLEKMSAEKISE 734 G I + NDK+ I+NK N E + E M A Sbjct: 545 SSSNDGGDISPIAIIPNDKQPNSIFNSKEPIIINKRLNLDTEGGGDEEDQEIMQAFAEQG 604 Query: 735 LLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESI-AVMEDRRY 793 LL +N Q K Q +Q R Y++ I EL +Y+ +IC +E+ +M D + Sbjct: 605 LLKNLNW--QGKGQLVGAQQKALQIRQNYLKQILGEL-EYQ-QICEMEKIFDEIMRDNKS 660 Query: 794 SLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQK 853 +Q+ + YS +EL+ +L D V+++QL E++ +L++ Sbjct: 661 ------------VQDLRMKYSNIL---EELIKKLHQFKDKHEVLQQQLNELQQNCVKLRE 705 Query: 854 KNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHE 913 +NQ + E + L+++++ ++ + ++T L +Y+ + L+ H+ Sbjct: 706 ENQKISNEYKKQMQKLNELKERLEKVITERDQTCLL---LNRYEKKEIITIKELQMEYHK 762 Query: 914 HQTLIVQKKKEIEDLE 929 + ++Q ++E++ L+ Sbjct: 763 KEEDLIQCQEEVDSLK 778 Score = 45.2 bits (102), Expect = 0.015 Identities = 84/412 (20%), Positives = 173/412 (41%), Gaps = 39/412 (9%) Query: 145 THLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXX 204 + + N KE N + +++K +E ++ Q++++EK QI+ + Sbjct: 3544 SEIQNKEKELANFQNSNSIQIKNLEEQLIQSQKELDEKKQILSQLEERQKESELSIKQLQ 3603 Query: 205 XXXXXXXED-----TKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKL 259 E+ T Q TK ++ I + + EKQ L D +S+ + L EA+ Sbjct: 3604 EKLSQKQEEVVHLQTTQNATKEEKISILLSQIQELEKQ--LSDSKSEMKNKNQLSEAS-- 3659 Query: 260 LEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIA 319 L A+ +I++ LEQ KQ++E S +EK E+ + E++ Sbjct: 3660 LNEAKEKITI--------LEQKYSNLQKNYSLLESELKQALEKSKKEKDELIQTHQQELS 3711 Query: 320 NMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTA 379 + + E + LN QI + ++ K + + S K+ L ++ + + Sbjct: 3712 QVQK-----EFIT-LNSQIEKNKIDMIEKDSQIKRISIEHDETQKQLESL--KQKYQQSL 3763 Query: 380 SKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXX 439 +++ S+++ DK ++I +L+ Q+ D ++KEY ++ Sbjct: 3764 EQLQLKESEITQLKKQMQLDKYEALSQIEQLKRE-QNNQIDQINKEY----QEKIQKLQS 3818 Query: 440 XXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVK 499 G D AQ + +Q +E I G++ E N I K++EQ ++ + + ++ Sbjct: 3819 ELQKGNDE--AQ---KLRQQIESLQAISQGSSNEMQNLIQKMKEQQEENVK---SNQSIA 3870 Query: 500 DLIEKLKSAEEQITQLNDEIDAANKNMIKVKS-NHKLKLKQMQKTIDNFSKV 550 +L +L + Q +LN +I + ++ LK ++ Q + NF ++ Sbjct: 3871 ELQSQLVKSNLQANELNQKISKLESKLQSTENFIDALKKQENQSSKSNFGRI 3922 Score = 42.7 bits (96), Expect = 0.080 Identities = 98/491 (19%), Positives = 200/491 (40%), Gaps = 33/491 (6%) Query: 560 LTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLL 619 L ++LH K L+++ LQ + V S+ YKK ++ N + RL+ + Sbjct: 675 LIKKLHQFKDKHEVLQQQLNELQQNCVKLREENQKISNEYKKQMQKLNELKERLEKVITE 734 Query: 620 ESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELA 679 Q +L +Y++ E + I +LQ + E + +E++D+L +L Sbjct: 735 RDQTC-------LLLNRYEKKE--IITIKELQMEYHKKEEDLIQCQEEVDSLKNQIDQLL 785 Query: 680 LVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKI 739 ++ +KE + ++NK ++I E + IS LL++I Sbjct: 786 GIVGMFDSEKELAKQMHNESIQQFSIVLNKYDDFIIRLFQDYCHFEDNITQNISSLLSEI 845 Query: 740 NHEEQSK-IQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERK 798 SK I ++ I+ I N + + L M + Y++ Sbjct: 846 IINVHSKDILDRY---ESIKRSIAQIYNKGRNNIQNVNNPSSLPPLNTQMPN-SYNIPGN 901 Query: 799 ADQLGSY--LQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIE-HENKELQKKN 855 D + SY L + ++ + + + + L + +V Q + +++ + Q Sbjct: 902 RDSIRSYSPLLITNQLLNQNIPPQQNINMQSSFLQNTSGLVNGQFITNNVNKSSDYQYSC 961 Query: 856 QILLEENQNLQI---SLSDMQQHYN-ALVEKANRTDLAESESTKYQTQLRDLESNLKRIT 911 L + + QI D+ + N + ++ R E E + + QL +LE ++ Sbjct: 962 SSLDKNPTHPQIEDEEEEDVNEVNNLEISQRRQRRRDLEDEISNLKGQLAELEKKNNQLV 1021 Query: 912 HEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQ-EYKNN 970 E Q K+ + +E+ F +++E I L EK ++ I+ V Q+ ++ + K+ Sbjct: 1022 TERMHDYDQMKEHEQRVEL-FKSKLEQKITQ---LKEKEKQFIQMVRQITPEIDLKDKDE 1077 Query: 971 IENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEII-ALN 1029 I+ + + + K+ +LI +Q+QQ+ +Q N+ N+ L ++ + LN Sbjct: 1078 IDYFEIKNQIVKKIQQDLI---MQQQQSSLSSILQQ--NQDNQSETLSGAGVQKYLQELN 1132 Query: 1030 QKINN-AQVSY 1039 I Q+SY Sbjct: 1133 NSIQQIKQISY 1143 Score = 41.9 bits (94), Expect = 0.14 Identities = 89/444 (20%), Positives = 183/444 (41%), Gaps = 72/444 (16%) Query: 918 IVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMN 977 I++ K ++DL ++++ +E I+ +K+E L+ QL E + N L Sbjct: 654 IMRDNKSVQDLRMKYSNILEELIKKLHQFKDKHE-------VLQQQLNELQQNCVKLR-- 704 Query: 978 VEELNKMNLELIDKHVQKQQTQSPDYTEQYINEI-NKLNALLKQKDEEIIALNQKINNAQ 1036 EE K++ E K +QK +NE+ +L ++ ++D+ + LN+ Sbjct: 705 -EENQKISNE-YKKQMQK------------LNELKERLEKVITERDQTCLLLNRYEKKEI 750 Query: 1037 VSYMSMVSDYESK---LAQFTTKLENMEEEMQRV--------SKQLLDSKQHNEELQ--- 1082 ++ + +Y K L Q ++++++ ++ ++ S++ L + HNE +Q Sbjct: 751 ITIKELQMEYHKKEEDLIQCQEEVDSLKNQIDQLLGIVGMFDSEKELAKQMHNESIQQFS 810 Query: 1083 ILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXL 1142 I++ + DD I L + FE NI + ISS + + + ++ D Sbjct: 811 IVLNKYDDFIIRLFQDYCHFEDNITQN----ISSLLSEIIINVHSKDILDRYESIKRSIA 866 Query: 1143 KVQEEEEFIQERSVLQEQSAKLNTELQECYT--------KIIQLETLNTELTGHDVVNQE 1194 ++ + + LNT++ Y + + +L ++ Q+ Sbjct: 867 QIYNKGRNNIQNVNNPSSLPPLNTQMPNSYNIPGNRDSIRSYSPLLITNQLLNQNIPPQQ 926 Query: 1195 QINQLKSKLE--------QLNTENDNLLSTVAELRSSIS------SAVDQRGFEIAELWK 1240 IN S L+ Q T N N S SS+ D+ ++ E+ Sbjct: 927 NINMQSSFLQNTSGLVNGQFITNNVNKSSDYQYSCSSLDKNPTHPQIEDEEEEDVNEVNN 986 Query: 1241 QHLAQREADFQKTEHE---LRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQ-VTSLQ 1296 ++QR + E E L+ QL+ E K QL+ + + +++ EQ V + Sbjct: 987 LEISQRRQRRRDLEDEISNLKGQLAELEKKNNQLV----TERMHDYDQMKEHEQRVELFK 1042 Query: 1297 NKLQDKEEHLRNLQEKYADVINQI 1320 +KL+ K L+ ++++ ++ QI Sbjct: 1043 SKLEQKITQLKEKEKQFIQMVRQI 1066 Score = 38.7 bits (86), Expect = 1.3 Identities = 30/111 (27%), Positives = 60/111 (54%), Gaps = 6/111 (5%) Query: 1433 EFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKE-SEIER--VKLIE 1489 E E + +++ K ++DL + + L L K+H+ + +E +Q++ +E+++ VKL E Sbjct: 646 EMEKIFDEIMRDNKSVQDLRMKYSNILEELIKKLHQFKDKHEVLQQQLNELQQNCVKLRE 705 Query: 1490 ELNVKITESVSLNKQ-VAELNKALEEEVAKTNEMQTALENQE-IEIVTLND 1538 E N KI+ Q + EL + LE+ + + ++ L E EI+T+ + Sbjct: 706 E-NQKISNEYKKQMQKLNELKERLEKVITERDQTCLLLNRYEKKEIITIKE 755 >UniRef50_A2EZ87 Cluster: Viral A-type inclusion protein, putative; n=2; cellular organisms|Rep: Viral A-type inclusion protein, putative - Trichomonas vaginalis G3 Length = 2271 Score = 187 bits (455), Expect = 3e-45 Identities = 273/1313 (20%), Positives = 572/1313 (43%), Gaps = 127/1313 (9%) Query: 296 AKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTE 355 A+ +IE EE + ++ L + +T+K + ++ + + K NK M Sbjct: 112 AQSAIEKLREENETMRKENKLLATKLQAITEKYKSIKEKDRTLLDNYKVASNKFREM--R 169 Query: 356 SKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQ 415 +K S+ + G + S+ T K+ Q LNQ + + NE+ + Sbjct: 170 NKYESNIRQYGQVVDSK---METDQKLVDLMQQ-QQNLLNQKNELEAKLNEVTTNNESLA 225 Query: 416 SLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDV 475 + NK L +K+Y + + A+ + + N + + Sbjct: 226 AKNKSL-EKQYRDLQNQVEDLNNQNIDLQNEAESAKNSAVKVTRALKKAERKLAKNEQQI 284 Query: 476 NEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKL 535 E ++ ++ QE ++E + +++ + L+SA+E++ +L E N +K K+N+KL Sbjct: 285 EEHERIHKE-HQEAHEE-SNKQLQECTKLLQSAQEKLKELQLE-----NNDLK-KANNKL 336 Query: 536 KLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIE 595 T DN +K+ ++ + + + ++Q + +E EK LQ L Y + Sbjct: 337 -------TRDN-TKLQNNVAKHEKSVSMMESMNQSIQNIESEKSELQNQLQQY------Q 382 Query: 596 SDVYKKMIEMENL---AETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQS 652 ++ K++ E+E L ET + L+++ L + L LQ D + + L+ Sbjct: 383 QEIAKRLKEIEGLQKQTETLFNKNNTLQNENSALTENLSQLQ---DNLSKSKKEAKSLRK 439 Query: 653 DQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQN 712 + + ++++ ++ I AL S + I++L+ D E I+ E+ +++ ++ Q Sbjct: 440 QGITAAKEALNFQQNIVALQKSLLDAHHEIDDLRRDVEDKNSKIQANESRVKELEDQNQL 499 Query: 713 YIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELS 772 EN DL ++ ++ + K E+ K ++E + K+QT ID Q+ D ++ + + Sbjct: 500 LEDENKDLEEEAQQYISNKEEEMNKKKSNEVK-KLQTL--IDQLKQQND----QLQQQNN 552 Query: 773 KYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMD 832 + I + EE +A +ED + + ++ Q Q K K + + DEL N++ L Sbjct: 553 ELHDEIEQKEEDLAKLEDEKQQIFQQNQQ----RQLKIKELTNKSQNNDELQNQIKQLKS 608 Query: 833 HDRVVEKQLLEIEHE----NKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDL 888 + QL ++ +E +KE++++N+ L + + +S +Q + E A + + Sbjct: 609 ELENTQNQLQKVTNEKGDKSKEIEEQNKKLKSQIEERDQMISKLQDENQKIAETAEQAAI 668 Query: 889 AESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNE 948 SE+ K L K++ E+ +L + +K+++DL + + + E ++ KK +E Sbjct: 669 KSSETNK------KLREQFKKVYAENTSLKAKNEKQVQDLMQQLDEK-EKQLQSKK--DE 719 Query: 949 KYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYI 1008 Y++ + + + L + IEN + +EE + N+ + ++++ + + + Sbjct: 720 NYKQENDQLKKENQDLMDKLKEIENERVELEE-DVKNVTTEKEDLEEEIEKLKEKVDVLE 778 Query: 1009 NEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVS 1068 +++ L K++ E Q+IN + M M+ D K+ T+L+N + Sbjct: 779 DQLETLTDEHKKQQEN---HEQQINKSNDENM-MLRDQMKKIFAENTQLKNTN------T 828 Query: 1069 KQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNV 1128 Q L+ Q N +LQ + E+D QIK+ ++ E++ KT+ ++ S + ++D V Sbjct: 829 NQELELAQKNHDLQRKLDEKDQQIKQKQD-----EIDELKTK-VLASEEFQKTTNDLQRV 882 Query: 1129 DXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQL-ETLNTELTG 1187 LK E +++ + K N E+Q +I+ L E + + Sbjct: 883 AEELKEKTKQIDDLKNINE----NLQNIKNDDLKKANEEIQNKQKQIVDLQEKIKETIKE 938 Query: 1188 HDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAEL--WKQHLAQ 1245 ++ +NQ+ + +L+ +LE L E+ T + I+ AVD+ I ++ K Sbjct: 939 NEELNQKNL-ELEEELEALTEEHKKQQETHEQ---QINKAVDENTKLIDQMKKLKNTNTN 994 Query: 1246 READFQKTEHELRVQLSAFESKYEQLLDSVQS--------STQEETNKIVTMEQVTSLQN 1297 +E + + H+L+ Q++ + E LL+ +QS Q++ N + + Q Sbjct: 995 QELELAQKNHDLQKQVNDLKKSNEDLLNQIQSDDSKKTIEDLQKQVNDLKISNEYLLKQI 1054 Query: 1298 KLQDKEEHLRNLQEKYADVINQIE----ILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLR 1353 + D + + L++ D+ + + IL+ +++ R Sbjct: 1055 QNNDSQAQIEELKKSNDDLQKKYDENEKILKDLLQENNALEEQFKEISRMNDHLKGETER 1114 Query: 1354 TE--NQSYK---QMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQ 1408 E N YK Q +++ I ++ EN L K + + D + K+ +L Sbjct: 1115 QENINNRYKQSSQKKDEVISELHNENDDLSKEN-------DDLTKEIEDLKTKISKLNED 1167 Query: 1409 LELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHE 1468 + + ++ + + LTQ+ND +EN+ ++ + +K EDLT E E +A E Sbjct: 1168 HKKEIKQLLDQIEQKNDLLTQQND-YENLMKENDDLDKENEDLTKENEQLVAEKETLCQE 1226 Query: 1469 NANHYETMQKESEIERVKLIEELNVKITESV-SLNKQVAELNKALEEEVAKTNEMQTALE 1527 N E ++K ++ K+ +E+ ++ + + +L K+ L K E+ + N ++ A Sbjct: 1227 N----ERLKK--ALDDSKIFDEIQKELQDKIDNLEKENDNLKKENEKIQSLKNALELAKS 1280 Query: 1528 NQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQL--DNTMNK 1578 + E ++ DEI L+ IQK + F + +E L +N M K Sbjct: 1281 TFDKE-KSIEDEIRKLEK----EHKDIQKQI-FGDKQNEEEEEDLSDENEMTK 1327 Score = 170 bits (413), Expect = 3e-40 Identities = 264/1351 (19%), Positives = 586/1351 (43%), Gaps = 105/1351 (7%) Query: 306 EKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKK 365 +K E+E K + N L K + LE ++ ++L N+ + E+++ + + K Sbjct: 206 QKNELEAKLNEVTTNNESLAAKNKSLEKQYRDLQNQVEDLNNQNIDLQNEAESAKNSAVK 265 Query: 366 GSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKE 425 + + +K+ R A + +Q+ ++ NK ++ + ++QS + L KE Sbjct: 266 VTRAL-KKAERKLAKNEQQIEEHERIHKEHQEAHEESNK-QLQECTKLLQSAQEKL--KE 321 Query: 426 YVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIH-VGTNTEDV-NEIAKVQE 483 + D +D +LQ +H + S++ + + +++ +E +++Q Sbjct: 322 LQLENNDLKKANNKLT---RDN--TKLQNNVAKHEKSVSMMESMNQSIQNIESEKSELQN 376 Query: 484 QLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKT 543 QL+Q + K +K+ IE L+ E + N+ + N + + S + L + +K Sbjct: 377 QLQQYQQEIAK--RLKE-IEGLQKQTETLFNKNNTLQNENSALTENLSQLQDNLSKSKKE 433 Query: 544 IDNFSKVS-DSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKM 602 + K + KE + + + L + + + E +L+ + D +S K++ Sbjct: 434 AKSLRKQGITAAKEALNFQQNIVALQKSLLDAHHEIDDLRRDVEDKNSKIQANESRVKEL 493 Query: 603 IEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQL--QSDQVCSEIK 660 + L E K + E+Q++ +E + ++K +EV+ I QL Q+DQ+ + Sbjct: 494 EDQNQLLEDENKDLEE-EAQQYISNKEEEMNKKKSNEVKKLQTLIDQLKQQNDQLQQQNN 552 Query: 661 SVH-----LEEQIDALSASKKEL-------ALVIENL---KLDKEQLYGTIKDLENDKED 705 +H EE + L K+++ L I+ L + ++L IK L+++ E+ Sbjct: 553 ELHDEIEQKEEDLAKLEDEKQQIFQQNQQRQLKIKELTNKSQNNDELQNQIKQLKSELEN 612 Query: 706 IMNKLQNYIQENMDLTDKLE------KMSAEKISELLAKINHEEQSKIQT--QFGIDAKI 757 N+LQ E D + ++E K E+ ++++K+ E Q +T Q I + Sbjct: 613 TQNQLQKVTNEKGDKSKEIEEQNKKLKSQIEERDQMISKLQDENQKIAETAEQAAIKSSE 672 Query: 758 QERDL--YIENIESELSKYKSRICR-LEESIAVMEDRRYSLERKADQLGSYLQEKQKAYS 814 + L + + +E + K++ + +++ + ++++ L+ K D+ +Y QE + Sbjct: 673 TNKKLREQFKKVYAENTSLKAKNEKQVQDLMQQLDEKEKQLQSKKDE--NYKQENDQLKK 730 Query: 815 EYTIQED---ELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSD 871 E D E+ N L + + V + ++E E ++L++K +L ++ + L Sbjct: 731 ENQDLMDKLKEIENERVELEEDVKNVTTEKEDLEEEIEKLKEKVDVLEDQLETLTDEHKK 790 Query: 872 MQQHYNALVEKANRTDLAESESTKY----QTQLRDLESNLKRITHEHQTLIVQKKKEIED 927 Q+++ + K+N ++ + K TQL++ +N + + + +Q+K + +D Sbjct: 791 QQENHEQQINKSNDENMMLRDQMKKIFAENTQLKNTNTN-QELELAQKNHDLQRKLDEKD 849 Query: 928 LEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIE---NLNMNVEELNKM 984 +I+ ++ K + +E+++K + ++ +L+E I+ N+N N++ + Sbjct: 850 QQIKQKQDEIDELKTKVLASEEFQKTTNDLQRVAEELKEKTKQIDDLKNINENLQNIKND 909 Query: 985 NLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQK----DEEIIALNQKINNAQVSYM 1040 +L+ ++ +Q +Q Q D E+ I E K N L QK +EE+ AL ++ Q ++ Sbjct: 910 DLKKANEEIQNKQKQIVDLQEK-IKETIKENEELNQKNLELEEELEALTEEHKKQQETHE 968 Query: 1041 SMVS---DYESKLAQFTTKLEN--------MEEEMQRVSKQLLDSKQHNEELQILVREQD 1089 ++ D +KL KL+N + ++ + KQ+ D K+ NE+L + + D Sbjct: 969 QQINKAVDENTKLIDQMKKLKNTNTNQELELAQKNHDLQKQVNDLKKSNEDLLNQI-QSD 1027 Query: 1090 DQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEE-- 1147 D K +++ L ++N K + I+ +D ++ E+ Sbjct: 1028 DSKKTIED--LQKQVNDLKISNEYLLKQIQN-NDSQAQIEELKKSNDDLQKKYDENEKIL 1084 Query: 1148 EEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLN 1207 ++ +QE + L+EQ +++ + + E +N E I++L ++ + L+ Sbjct: 1085 KDLLQENNALEEQFKEISRMNDHLKGETERQENINNRYKQSSQKKDEVISELHNENDDLS 1144 Query: 1208 TENDNLLSTVAELRSSISSAVDQRGFEIAEL-----WKQHLAQREADFQ---KTEHELRV 1259 END+L + +L++ IS + EI +L K L ++ D++ K +L Sbjct: 1145 KENDDLTKEIEDLKTKISKLNEDHKKEIKQLLDQIEQKNDLLTQQNDYENLMKENDDLDK 1204 Query: 1260 QLSAFESKYEQLLDSVQSSTQEETNKIVTMEQ---VTSLQNKLQDKEEHLRNLQEKYADV 1316 + + EQL+ ++ QE ++ +Q +LQDK ++L + Sbjct: 1205 ENEDLTKENEQLVAEKETLCQENERLKKALDDSKIFDEIQKELQDKIDNLEKENDNLKKE 1264 Query: 1317 INQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQ-EQSILNINEENA 1375 +I+ L++ +E K F + Q + Q E+ ++++EN Sbjct: 1265 NEKIQSLKNALELAKSTFDKEKSIEDEIRKLEKEHKDIQKQIFGDKQNEEEEEDLSDENE 1324 Query: 1376 QLK-KSSXXXXXXXXXXXXRVNDAEAKVLELTHQL-ELKDSEI-YQKTHEYTITLTQRND 1432 K + +VN+ + L H+L + +D+ + + L Q + Sbjct: 1325 MTKIRREVEDLKKDALIQIKVNE----IQRLEHELSQAQDNSVPLVQFQSMADNLEQTVE 1380 Query: 1433 EFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELN 1492 E + +++++ + + + + SEL I + + + E E +KL ++L Sbjct: 1381 ENKQLKEKMKLIDNELTNKLEFENSELKIDLDNYSKQLDDANAKISKLEKENIKLKDKLE 1440 Query: 1493 VKITE--SVSLNKQVAELNKALEEEVAKTNEM----QTALENQEIEIVTLNDEITNLQNM 1546 + +E + + + ++ A+ ++ K + +T + E E TL +++ L+N Sbjct: 1441 KEESEKSDMIIKYENLKMENAVSGDIDKIKDQLKDKETDIVGLEAERNTLMKKLSELENK 1500 Query: 1547 VRASSSKIQKHVSFASDTKQGRDEQLDNTMN 1577 V+ + KI K + + EQL+N N Sbjct: 1501 VQENDEKI-KEIEDLKKENEELKEQLENNNN 1530 Score = 149 bits (361), Expect = 6e-34 Identities = 295/1395 (21%), Positives = 600/1395 (43%), Gaps = 156/1395 (11%) Query: 216 QQMTKMQENFIAMEAEWKD---EKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHS 272 ++ Q+N +A++ D E L +D+E K+ +I + E K LE + E+ Sbjct: 446 KEALNFQQNIVALQKSLLDAHHEIDDLRRDVEDKNSKIQANESRVKELEDQNQLLEDENK 505 Query: 273 KLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLE 332 L +E +Q ++ E+ +K S E+ + L I+ L+ Sbjct: 506 DLEEEAQQYIS---------------------NKEEEMNKKKSNEVKKLQTL---IDQLK 541 Query: 333 HLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSE 392 N Q++Q N EL +++ + + ++ + + R K + SQ + E Sbjct: 542 QQNDQLQQQNNELHDEIEQKEEDLAKLEDEKQQ---IFQQNQQRQLKIKELTNKSQNNDE 598 Query: 393 TLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQL 452 NQ K K+E+ + +Q + + DK I E++ +D +I++L Sbjct: 599 LQNQI---KQLKSELENTQNQLQKVTNEKGDKSKEIEEQNKKLKSQIEE---RDQMISKL 652 Query: 453 QLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQEL--NDEIKDVN---VKDLIEKLKS 507 Q E+Q+ E + + N+ K++EQ K+ N +K N V+DL+++L Sbjct: 653 QDENQKIAETAE--QAAIKSSETNK--KLREQFKKVYAENTSLKAKNEKQVQDLMQQLDE 708 Query: 508 AEEQITQLNDEIDAANKNMIKVKSNHKL--KLKQMQ-KTIDNFSKVSDSNKEIVRLTEEL 564 E+Q+ DE + +K K N L KLK+++ + ++ V + E L EE+ Sbjct: 709 KEKQLQSKKDENYKQENDQLK-KENQDLMDKLKEIENERVELEEDVKNVTTEKEDLEEEI 767 Query: 565 HHLSQKVAELEEEKGNL-QLHLVDYDSG--RMIESDVYKKMI--EMENLAETRLKAISLL 619 L +KV LE++ L H ++ ++ +S+ M+ +M+ + + + Sbjct: 768 EKLKEKVDVLEDQLETLTDEHKKQQENHEQQINKSNDENMMLRDQMKKIFAENTQLKNTN 827 Query: 620 ESQKFDLVQELHILQQKYDE----VEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASK 675 +Q+ +L Q+ H LQ+K DE ++ K +I +L++ + SE + + ++ Sbjct: 828 TNQELELAQKNHDLQRKLDEKDQQIKQKQDEIDELKTKVLASE-EFQKTTNDLQRVAEEL 886 Query: 676 KELALVIENLKLDKEQLYGTIKD-LENDKEDIMNK------LQNYIQENMDLTDKLEKMS 728 KE I++LK E L D L+ E+I NK LQ I+E + ++L + + Sbjct: 887 KEKTKQIDDLKNINENLQNIKNDDLKKANEEIQNKQKQIVDLQEKIKETIKENEELNQKN 946 Query: 729 AEKISELLAKIN-HEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAV 787 E EL A H++Q + Q I+ + E I+ ++ + ++ L + Sbjct: 947 LELEEELEALTEEHKKQQETHEQ-QINKAVDENTKLIDQMKKLKNTNTNQELELAQKNHD 1005 Query: 788 MEDRRYSLERKADQLGSYLQ--EKQKAYSEYTIQEDELV--NRLAVLMDHDRVVEKQLLE 843 ++ + L++ + L + +Q + +K + Q ++L N + + + Q+ E Sbjct: 1006 LQKQVNDLKKSNEDLLNQIQSDDSKKTIEDLQKQVNDLKISNEYLLKQIQNNDSQAQIEE 1065 Query: 844 IEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDL 903 ++ N +LQKK +EN+ + L D+ Q NAL E+ + ++ Sbjct: 1066 LKKSNDDLQKK----YDENEKI---LKDLLQENNALEEQFKEISRMNDHLKGETERQENI 1118 Query: 904 ESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKV----LNEKYEKNI-EYVT 958 + K+ + + +I + E +DL E N + I D K LNE ++K I + + Sbjct: 1119 NNRYKQSSQKKDEVISELHNENDDLSKE-NDDLTKEIEDLKTKISKLNEDHKKEIKQLLD 1177 Query: 959 QLEAQ--LQEYKNNIENLNMNVEELNKMNLELIDKHVQ---KQQT--QSPDYTEQYINEI 1011 Q+E + L +N+ ENL ++L+K N +L ++ Q +++T Q + ++ +++ Sbjct: 1178 QIEQKNDLLTQQNDYENLMKENDDLDKENEDLTKENEQLVAEKETLCQENERLKKALDDS 1237 Query: 1012 NKLNALLKQKDEEIIAL-----NQKINNAQV----SYMSMVSDYESKLAQFTTKLENMEE 1062 + + K+ ++I L N K N ++ + + + K ++ +E+ Sbjct: 1238 KIFDEIQKELQDKIDNLEKENDNLKKENEKIQSLKNALELAKSTFDKEKSIEDEIRKLEK 1297 Query: 1063 EMQRVSKQLLDSKQHNEELQILVREQD-DQIK-ELKETKLTFEMNIPKTEGMIISSTIEP 1120 E + + KQ+ KQ+ EE + L E + +I+ E+++ K + I E + + Sbjct: 1298 EHKDIQKQIFGDKQNEEEEEDLSDENEMTKIRREVEDLKKDALIQIKVNEIQRLEHELSQ 1357 Query: 1121 MSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQ-EQSAKL---NTELQ---ECYT 1173 D N+V V+E ++ ++ ++ E + KL N+EL+ + Y+ Sbjct: 1358 AQD--NSVPLVQFQSMADNLEQTVEENKQLKEKMKLIDNELTNKLEFENSELKIDLDNYS 1415 Query: 1174 KIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGF 1233 K QL+ N +++ + +E I +LK KLE+ +E +++ L+ + +AV Sbjct: 1416 K--QLDDANAKISK---LEKENI-KLKDKLEKEESEKSDMIIKYENLK--MENAVSG--- 1464 Query: 1234 EIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVT 1293 +I ++ K L +E D E E + ++ ++ + + E K E Sbjct: 1465 DIDKI-KDQLKDKETDIVGLEAERNTLMKKLSELENKVQENDEKIKEIEDLKKENEELKE 1523 Query: 1294 SLQNKLQDKEEHLRN----LQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXX 1349 L+N D EE L+N L+ + + N++E+ SE++ +K Sbjct: 1524 QLENNNNDVEERLQNDNNMLKREITKLKNKLEL--SEVDKKK------ADEGVKTMMEKY 1575 Query: 1350 XDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQL 1409 + EN K E+ L+ N+E K++ V ++ E Sbjct: 1576 NKISEENMLLKHHIEE--LSQNKEEKSDKENLNESKPLSSGLATPVKSKDSFFGE----- 1628 Query: 1410 ELKDSEIYQKTHEYTITLTQR-----NDEFENVRQQLVEYEKRIEDLTYEK---ESELAI 1461 + ++ T ++ T + R DEF++ E E+ I+++ EK L Sbjct: 1629 DSSSDNLFNITQPHSSTSSPRRQYMVEDEFDS-NNSHKEEEEEIDEVKPEKGLINLSLDA 1687 Query: 1462 LRLKMHENANHYETMQKESEIERVKLIEEL--NVKITESVSLNKQ-VAELN-KALEEEVA 1517 ++ K + +K E E+ K EE+ +++ +++ K + E++ K L+E Sbjct: 1688 IKQKYERRRSSAAQPKKSDEEEQTKEEEEIVSGIEVIDNLEPPKSPLREISEKDLDENFP 1747 Query: 1518 KTNEMQTALENQEIE 1532 + + LEN++++ Sbjct: 1748 DVSSSNSPLENEDMK 1762 Score = 128 bits (309), Expect = 1e-27 Identities = 212/1011 (20%), Positives = 414/1011 (40%), Gaps = 103/1011 (10%) Query: 665 EEQIDALSASKKELALVIENLKLDKEQLYGT---IKDLENDKEDIMNKLQNYI----QEN 717 ++ I A +EL + +L+ +Q Y T + D + + + I LQ I Q N Sbjct: 26 QKTIQTYQAQVQELTDQVRDLESRLDQSYNTQTQMFDSDTENQSIQQTLQERIRQLSQRN 85 Query: 718 MDLTDKLEKMSAEKISELLAKI-NHEEQSKIQT-QFGIDAKIQERDLYIENIESELSKYK 775 +L + A ++ A I N E QS I+ + + +E L +++ KYK Sbjct: 86 SELKNSRINSPAVSSTKRSASIANPEAQSAIEKLREENETMRKENKLLATKLQAITEKYK 145 Query: 776 SRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDR 835 S ++E + D K ++ + + + Y + + E +L LM + Sbjct: 146 S----IKEKDRTLLDNYKVASNKFREMRNKYESNIRQYGQVVDSKMETDQKLVDLMQQQQ 201 Query: 836 VVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHY----NALVEKANRTDLAES 891 + Q E+E + E+ N+ L +N++L+ D+Q N ++ N + A++ Sbjct: 202 NLLNQKNELEAKLNEVTTNNESLAAKNKSLEKQYRDLQNQVEDLNNQNIDLQNEAESAKN 261 Query: 892 ESTKYQTQLRDLESNL----------KRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIR 941 + K L+ E L +RI EHQ + K++++ + + ++ Sbjct: 262 SAVKVTRALKKAERKLAKNEQQIEEHERIHKEHQEAHEESNKQLQEC-TKLLQSAQEKLK 320 Query: 942 DKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMN--LELIDKHVQKQQTQ 999 + ++ N +K +T+ +LQ NN+ +V + MN ++ I+ + Q Q Sbjct: 321 ELQLENNDLKKANNKLTRDNTKLQ---NNVAKHEKSVSMMESMNQSIQNIESEKSELQNQ 377 Query: 1000 SPDYTEQYINEINKLNALLKQKDEEIIALN--QKINNAQVSYMSMVSDYESKLAQFTTKL 1057 Y ++ + ++ L KQ + N Q N+A +S + D SK + L Sbjct: 378 LQQYQQEIAKRLKEIEGLQKQTETLFNKNNTLQNENSALTENLSQLQDNLSKSKKEAKSL 437 Query: 1058 E-----------NMEEEMQRVSKQLLDSKQHNEELQILVREQ-------DDQIKELKETK 1099 N ++ + + K LLD+ ++L+ V ++ + ++KEL++ Sbjct: 438 RKQGITAAKEALNFQQNIVALQKSLLDAHHEIDDLRRDVEDKNSKIQANESRVKELEDQN 497 Query: 1100 LTFE---MNIPKTEGMIISSTIEPM----SDDANNVDXXXXXXXXXXXXLKVQEEEEFIQ 1152 E ++ + IS+ E M S++ + L+ Q+ E Sbjct: 498 QLLEDENKDLEEEAQQYISNKEEEMNKKKSNEVKKLQTLIDQLKQQNDQLQ-QQNNELHD 556 Query: 1153 ERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVN---QEQINQLKSKLE----- 1204 E +E AKL E Q+ + + Q + ELT N Q QI QLKS+LE Sbjct: 557 EIEQKEEDLAKLEDEKQQIFQQNQQRQLKIKELTNKSQNNDELQNQIKQLKSELENTQNQ 616 Query: 1205 --QLNTENDNLLSTVAELRSSISSAVDQRGFEIAELW--KQHLA----QREADFQKTEHE 1256 ++ E + + E + S +++R I++L Q +A Q +T + Sbjct: 617 LQKVTNEKGDKSKEIEEQNKKLKSQIEERDQMISKLQDENQKIAETAEQAAIKSSETNKK 676 Query: 1257 LRVQL-------SAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNL 1309 LR Q ++ ++K E+ + + E+ ++ + + Q Q K+E+ ++L Sbjct: 677 LREQFKKVYAENTSLKAKNEKQVQDLMQQLDEKEKQLQSKKDENYKQENDQLKKEN-QDL 735 Query: 1310 QEKYADVINQIEILRSEIED---EKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQ--- 1363 +K ++ N+ L ++++ EK L T +K+ Q Sbjct: 736 MDKLKEIENERVELEEDVKNVTTEKEDLEEEIEKLKEKVDVLEDQLETLTDEHKKQQENH 795 Query: 1364 EQSILNINEENA----QLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQK 1419 EQ I N+EN Q+KK + + K +L +L+ KD +I QK Sbjct: 796 EQQINKSNDENMMLRDQMKKIFAENTQLKNTNTNQELELAQKNHDLQRKLDEKDQQIKQK 855 Query: 1420 THEYTITLTQ--RNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQ 1477 E T+ ++EF+ L + +++ T ++ +L + + +N + + + Sbjct: 856 QDEIDELKTKVLASEEFQKTTNDLQRVAEELKEKT-KQIDDLKNINENL-QNIKNDDLKK 913 Query: 1478 KESEIE-RVKLIEELNVKITESVSLNKQVAELNKALEEEV-AKTNEMQTALENQEIEIVT 1535 EI+ + K I +L KI E++ N+++ + N LEEE+ A T E + E E +I Sbjct: 914 ANEEIQNKQKQIVDLQEKIKETIKENEELNQKNLELEEELEALTEEHKKQQETHEQQINK 973 Query: 1536 LNDEITNL-QNMVRASSSKIQKHVSFASDTKQGRDEQLD-NTMNKELLDAV 1584 DE T L M + ++ + + A + + D N++LL+ + Sbjct: 974 AVDENTKLIDQMKKLKNTNTNQELELAQKNHDLQKQVNDLKKSNEDLLNQI 1024 Score = 124 bits (300), Expect = 2e-26 Identities = 209/1036 (20%), Positives = 449/1036 (43%), Gaps = 99/1036 (9%) Query: 147 LSNTIKEKDNALSVLQVK-MKIMETT------ILDLQEKINEKDQIIEAKNKATTXXXXX 199 L + I+E+D +S LQ + KI ET + +K+ E+ + + A+N T+ Sbjct: 638 LKSQIEERDQMISKLQDENQKIAETAEQAAIKSSETNKKLREQFKKVYAEN--TSLKAKN 695 Query: 200 XXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKL 259 E KQ +K EN+ + K E Q L+ ++ + LEE K Sbjct: 696 EKQVQDLMQQLDEKEKQLQSKKDENYKQENDQLKKENQDLMDKLKEIENERVELEEDVKN 755 Query: 260 LEAARFEISLEHSKLAQE---LEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSL 316 + + ++ E KL ++ LE +Q I S +E + ++ Sbjct: 756 VTTEKEDLEEEIEKLKEKVDVLEDQLETLTDEHKKQQENHEQQINKSNDENMMLRDQMKK 815 Query: 317 EIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSP-SKKGSPLISRKSG 375 A T+L K + L ++ Q N +L+ KL + K + + +++ + Sbjct: 816 IFAENTQL-KNTNTNQEL--ELAQKNHDLQRKLDEKDQQIKQKQDEIDELKTKVLASEEF 872 Query: 376 RNTASKMKSPWSQLSSETLNQDTDKKINKN-------EIAKLEMVIQSLNKDLVDKEYVI 428 + T + ++ +L +T D K IN+N ++ K IQ+ K +VD + I Sbjct: 873 QKTTNDLQRVAEELKEKTKQIDDLKNINENLQNIKNDDLKKANEEIQNKQKQIVDLQEKI 932 Query: 429 SEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQE 488 E + + L EH++ E H + V+E K+ +Q+K Sbjct: 933 KETIKENEELNQKNLELEEELEALTEEHKKQQE----THEQQINKAVDENTKLIDQMK-- 986 Query: 489 LNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMI-KVKSNHKLK-LKQMQKTIDN 546 ++K+ N +E + + Q+ND + +N++++ +++S+ K ++ +QK +++ Sbjct: 987 ---KLKNTNTNQELELAQKNHDLQKQVND-LKKSNEDLLNQIQSDDSKKTIEDLQKQVND 1042 Query: 547 FSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEME 606 K+ SN+ +++ + +Q + EL++ +LQ YD I K +++ Sbjct: 1043 L-KI--SNEYLLKQIQNNDSQAQ-IEELKKSNDDLQ---KKYDENEKI----LKDLLQEN 1091 Query: 607 NLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLAD-ISQLQSDQVCSEIKSVHLE 665 N E + K IS + + + +Y + K + IS+L ++ ++ L Sbjct: 1092 NALEEQFKEISRMNDHLKGETERQENINNRYKQSSQKKDEVISELHNENDDLSKENDDLT 1151 Query: 666 EQIDALSASKKELALVIENLKLDKEQLYGTIK---DL---ENDKEDIMNKLQNYIQENMD 719 ++I+ L K +++ + E+ K + +QL I+ DL +ND E++M + + +EN D Sbjct: 1152 KEIEDL---KTKISKLNEDHKKEIKQLLDQIEQKNDLLTQQNDYENLMKENDDLDKENED 1208 Query: 720 LTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRIC 779 LT + E++ AEK E L + N + + D +E I+N+E E K Sbjct: 1209 LTKENEQLVAEK--ETLCQENERLKKALDDSKIFDEIQKELQDKIDNLEKENDNLKKENE 1266 Query: 780 RLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEK 839 +++ +E + + + K + +++ +K + + IQ+ ++ + D E Sbjct: 1267 KIQSLKNALELAKSTFD-KEKSIEDEIRKLEKEHKD--IQKQIFGDKQNEEEEEDLSDEN 1323 Query: 840 QLLEIEHENKELQKKN--QILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQ 897 ++ +I E ++L+K QI + E Q L+ LS Q + LV Sbjct: 1324 EMTKIRREVEDLKKDALIQIKVNEIQRLEHELSQAQDNSVPLV----------------- 1366 Query: 898 TQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYV 957 Q + + NL++ E++ Q K++++ ++ E ++E + K+ + Y K ++ Sbjct: 1367 -QFQSMADNLEQTVEENK----QLKEKMKLIDNELTNKLEFENSELKIDLDNYSKQLD-- 1419 Query: 958 TQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNAL 1017 +A + K EN+ + ++L K E D ++ + + + +I+K+ Sbjct: 1420 ---DANAKISKLEKENIKLK-DKLEKEESEKSDMIIKYENLKMENAVS---GDIDKIKDQ 1472 Query: 1018 LKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQH 1077 LK K+ +I+ L + N + M +S+ E+K+ + K++ + E++++ +++L + ++ Sbjct: 1473 LKDKETDIVGLEAERN----TLMKKLSELENKVQENDEKIKEI-EDLKKENEELKEQLEN 1527 Query: 1078 NEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXX 1137 N + D+ + + + TKL ++ + + + ++ M + N + Sbjct: 1528 NNNDVEERLQNDNNMLKREITKLKNKLELSEVDKKKADEGVKTMMEKYNKISEENMLLKH 1587 Query: 1138 XXXXLKVQEEEEFIQE 1153 L +EE+ +E Sbjct: 1588 HIEELSQNKEEKSDKE 1603 Score = 67.3 bits (157), Expect = 3e-09 Identities = 194/1052 (18%), Positives = 419/1052 (39%), Gaps = 94/1052 (8%) Query: 109 KQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNALSVLQVKMKIM 168 KQ +L K + + + Q+ D+ +SN K + Q +++ + Sbjct: 1008 KQVNDLKKSNEDLLNQIQSDDSKKTIEDLQKQVNDLK-ISNEYLLKQIQNNDSQAQIEEL 1066 Query: 169 ETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAM 228 + + DLQ+K +E ++I++ + D + T+ QEN Sbjct: 1067 KKSNDDLQKKYDENEKILKDLLQENNALEEQFKEISRM-----NDHLKGETERQENINNR 1121 Query: 229 EAEWKDEKQRLLKDIESKDVRISSL-EEANKLLEAARFEISL---EHSK----LAQELEQ 280 + +K ++ ++ +++ +S ++ K +E + +IS +H K L ++EQ Sbjct: 1122 YKQSSQKKDEVISELHNENDDLSKENDDLTKEIEDLKTKISKLNEDHKKEIKQLLDQIEQ 1181 Query: 281 XXXXXXXXXXXXXXLAKQS-IEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIR 339 + + ++ E+ T+ E+ E + + ++++ + Sbjct: 1182 KNDLLTQQNDYENLMKENDDLDKENEDLTKENEQLVAEKETLCQENERLKKALDDSKIFD 1241 Query: 340 QTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTD 399 + KEL++K+ + E+ + ++K L +N KS + + E +D Sbjct: 1242 EIQKELQDKIDNLEKENDNLKKENEKIQSL------KNALELAKSTFDK---EKSIEDEI 1292 Query: 400 KKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQH 459 +K+ K E ++ I ++ ++E + E + KD LI Q+++ Q Sbjct: 1293 RKLEK-EHKDIQKQIFGDKQNEEEEEDLSDENEMTKIRREVEDLKKDALI-QIKVNEIQR 1350 Query: 460 MEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQL---- 515 +E H + +D N + VQ Q + ++ + N K L EK+K + ++T Sbjct: 1351 LE-----HELSQAQD-NSVPLVQFQSMADNLEQTVEEN-KQLKEKMKLIDNELTNKLEFE 1403 Query: 516 NDEIDAANKNMIKVKSNHKLKLKQMQKTI----DNFSKVSDSNKEIVRLTEELHHLSQKV 571 N E+ N K + K+ +++K D K +++ E L + Sbjct: 1404 NSELKIDLDNYSKQLDDANAKISKLEKENIKLKDKLEKEESEKSDMIIKYENLKMENAVS 1463 Query: 572 AELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELH 631 ++++ K L+ D + + KK+ E+EN + + I +E K + + Sbjct: 1464 GDIDKIKDQLKDKETDIVGLEAERNTLMKKLSELENKVQENDEKIKEIEDLKKENEELKE 1523 Query: 632 ILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQ 691 L+ ++VE++L + + + ++ + L E +D A + ++ + K+ +E Sbjct: 1524 QLENNNNDVEERLQNDNNMLKREITKLKNKLELSE-VDKKKADEGVKTMMEKYNKISEEN 1582 Query: 692 --LYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEK--------MSAEKISELLAKIN- 740 L I++L +KE+ +K +N + E+ L+ L + S+ L I Sbjct: 1583 MLLKHHIEELSQNKEEKSDK-EN-LNESKPLSSGLATPVKSKDSFFGEDSSSDNLFNITQ 1640 Query: 741 -HEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKA 799 H S + Q+ ++ + + + E E E+ + K + S+ ++ ++Y R Sbjct: 1641 PHSSTSSPRRQYMVEDEFDSNNSHKEE-EEEIDEVKPEKGLINLSLDAIK-QKYERRR-- 1696 Query: 800 DQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILL 859 S Q K+ E T +E+E+V+ + V+ D+ + L EI K+L + + Sbjct: 1697 ---SSAAQPKKSDEEEQTKEEEEIVSGIEVI-DNLEPPKSPLREI--SEKDLDENFPDVS 1750 Query: 860 EENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIV 919 N L+ DM+Q + +E A D S + Y S I +E Q+ + Sbjct: 1751 SSNSPLE--NEDMKQ-MSPKIEAAKYPDPKMSPKSIYAVPSSPKRS---MIENEIQSDDL 1804 Query: 920 QKKKEIEDLE-IEFNTQIESAIRDKKVLNEKY----EKNIEYVTQLEAQLQEYKNNIENL 974 ++ + E EFN S D VL E NIE + + + NN EN Sbjct: 1805 EQIDSFQSPESSEFNVVPHS--HDSYVLQNNSDTIPEINIEDTSSMHSNSSLVSNNQENK 1862 Query: 975 NMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINN 1034 N E + E + V++++ + D EQ + L+++++ E+I ++++ Sbjct: 1863 EENQNEFPEE--ENQNDLVEEEEQEQHDKEEQ-----ENHDDLVEEEEHEVINEEEEVHG 1915 Query: 1035 AQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKE 1094 + + E K + E+ EE++ + + ++ IL+ + + +E Sbjct: 1916 EE--------EEEKKPVDISVSSEHSEEDVAEEEENQFEEEEEGMYQYILINDGSELDEE 1967 Query: 1095 LKETKLTFEMNIPKTEGMIISSTIEPMSDDAN 1126 + E + + + + D+ N Sbjct: 1968 KPRRNIVIEEGVESEDAEEDENDVLDQYDNLN 1999 Score = 60.1 bits (139), Expect = 5e-07 Identities = 126/635 (19%), Positives = 251/635 (39%), Gaps = 73/635 (11%) Query: 950 YEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYIN 1009 Y+K I+ +AQ+QE + + +L +++ ++ D + Q Q ++ I Sbjct: 25 YQKTIQ---TYQAQVQELTDQVRDLESRLDQSYNTQTQMFDSDTENQSIQQT--LQERIR 79 Query: 1010 EINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSK 1069 ++++ N+ LK N +IN+ VS + + AQ + E E R Sbjct: 80 QLSQRNSELK---------NSRINSPAVSSTKRSASIANPEAQSAIEKLREENETMRKEN 130 Query: 1070 QLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVD 1129 +LL +K LQ + ++ K +KE T N + S+ M N Sbjct: 131 KLLATK-----LQAIT----EKYKSIKEKDRTLLDNYK-----VASNKFREM----RNKY 172 Query: 1130 XXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHD 1189 K++ +++ + ++Q+Q LN + E K+ ++ T N L + Sbjct: 173 ESNIRQYGQVVDSKMETDQKLVD---LMQQQQNLLNQK-NELEAKLNEVTTNNESLAAKN 228 Query: 1190 VVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVD-QRGFEIAELWKQHLAQREA 1248 ++Q L++++E LN +N +L + E S+ +SAV R + AE + LA+ E Sbjct: 229 KSLEKQYRDLQNQVEDLNNQNIDLQN---EAESAKNSAVKVTRALKKAE---RKLAKNEQ 282 Query: 1249 DFQKTEHELRVQLSAFESKYEQLLDSVQ--SSTQEETNKI-VTMEQVTSLQNKLQDKEEH 1305 ++ E + A E +QL + + S QE+ ++ + + NKL Sbjct: 283 QIEEHERIHKEHQEAHEESNKQLQECTKLLQSAQEKLKELQLENNDLKKANNKLTRDNTK 342 Query: 1306 LRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQ 1365 L+N K+ ++ +E + I++ + ++E Q+ Q +Q Sbjct: 343 LQNNVAKHEKSVSMMESMNQSIQNIESE-------------------KSELQNQLQQYQQ 383 Query: 1366 SILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTI 1425 I +E L+K + + + +L L E + + I Sbjct: 384 EIAKRLKEIEGLQKQTETLFNKNNTLQNENSALTENLSQLQDNLSKSKKEA-KSLRKQGI 442 Query: 1426 TLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERV 1485 T + E N +Q +V +K + D +E + + K + E+ KE E ++ Sbjct: 443 TAAK---EALNFQQNIVALQKSLLDAHHEIDDLRRDVEDK-NSKIQANESRVKELE-DQN 497 Query: 1486 KLIEELNVKITESVS--LNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNL 1543 +L+E+ N + E ++ + E+NK EV K + L+ Q ++ N+E+ + Sbjct: 498 QLLEDENKDLEEEAQQYISNKEEEMNKKKSNEVKKLQTLIDQLKQQNDQLQQQNNELHDE 557 Query: 1544 QNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNK 1578 +K++ Q R ++ NK Sbjct: 558 IEQKEEDLAKLEDEKQQIFQQNQQRQLKIKELTNK 592 >UniRef50_UPI00006CDA45 Cluster: hypothetical protein TTHERM_00402150; n=1; Tetrahymena thermophila SB210|Rep: hypothetical protein TTHERM_00402150 - Tetrahymena thermophila SB210 Length = 1762 Score = 186 bits (454), Expect = 3e-45 Identities = 222/1125 (19%), Positives = 484/1125 (43%), Gaps = 105/1125 (9%) Query: 505 LKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEEL 564 ++ A++QI L +E+ +KN LK M + I+ F + S +++ L EE+ Sbjct: 1 MEEAQQQIEDLKNELQKKDKN-----------LKDMTQKIEKFQQDSQEMEQM--LEEEI 47 Query: 565 HHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLE---S 621 +++ +L++E + + SG+ D K+ E+E E + IS L S Sbjct: 48 KIKEEEIEKLQQELEEKEEEIQQLKSGQQDTGDQNVKLEELEKQIEQNNEVISSLNDLIS 107 Query: 622 QKFDLVQELHILQQKY-DEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELAL 680 ++ LVQ +Q+Y D++++ +I LQ Q+ K+V +E++++ L K+ Sbjct: 108 KQIFLVQHTQQKEQEYKDQIDNSSREIKNLQQ-QLKEASKNVGVEQELEKLKNELKDSQS 166 Query: 681 VIENLKLDKEQLYGTIKDLE---NDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLA 737 +++ K + Q I ++ N KE L I+E + + K EK KI +L + Sbjct: 167 LLQKQKEENNQANQAISAMKEEINSKEKATESLSLQIKEQIQNSQKQEKELQIKIQQLES 226 Query: 738 KINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLER 797 +I + K + + ++ +L I+N +SEL K + I +SL+ Sbjct: 227 EIINSNAKKQEFK----TLLESNNLQIQNNKSELQKKEEHI--------------HSLQE 268 Query: 798 KADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQI 857 K DQL S LQ Q T + D+L +L + + K I+ + K+L+ K + Sbjct: 269 KYDQLLSQLQILQND----TSKSDQLKKMQNLLEEKQNEINK----IQQDKKDLETKVEN 320 Query: 858 LLEENQNLQISLSDMQQHYNALVEKANRTDLA----ESESTKYQTQLRD---LESNLKRI 910 L + N+ I L++++ + A E+ ++ ++ E++ K Q ++ +E + K+I Sbjct: 321 LNKNIDNISIQLNELKNEF-AQREQGYQSQISSQSQEAQKNKEIIQKKEEQIIELSQKQI 379 Query: 911 THEHQTLIVQKK-------KEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQ 963 ++Q ++Q K+++ E Q+ A+ +K L K + + + ++ + Sbjct: 380 QIQNQLQVLQNDTSKSDQLKQVQSTLFEKENQLNQALEVQKELQAKIQDEKKLIENIQKE 439 Query: 964 LQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDE 1023 + K + + N +K +LEL D+ +Q +Q + +Q + +NK N + Q + Sbjct: 440 ADQLKKTLNDKEFN----HKNSLELKDQEIQLKQAEIQKKEQQIEDLLNKQNQIQAQLLK 495 Query: 1024 EIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQI 1083 ++ L Q+ + D E ++ K+ E++ + + Q+ Q N++ Q+ Sbjct: 496 QLQHLLQERQDQIDQIQQSKRDLELQITNLNNKINQFEQKCKDLDLQINSLNQENQKKQV 555 Query: 1084 LVREQDDQIKELK-----ETKL-TFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXX 1137 + E +++ + +T+L E+ K E I+ + + + Sbjct: 556 QIEENKKELENKQQIFKSQTELQQKEIKESKAEIQKKQEIIQELQNKEKQLQSQLQIMLQ 615 Query: 1138 XXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQIN 1197 L + + E Q + ++ +L T ++ TK ++ + +L+ + N+++I Sbjct: 616 QLHKLLEERQNEISQVQENKKDIEQRLATLTKDYETKQVEFDETKKQLSDKEQQNKQEIQ 675 Query: 1198 QLKSKLEQLNTENDNLLSTV-AELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHE 1256 +L K+ + NL S + + + + +E L Q+++Q + K E E Sbjct: 676 KLSIKVIGYEKDLTNLQSKCQSYYEENQQKTLKLKEYEKKVLDSQNISQEK--ILKME-E 732 Query: 1257 LRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADV 1316 ++ + +YE+ + + Q ++ K +Q+ ++ E ++N ++ Sbjct: 733 IQKHCQQLQKQYEEQVQNEQKKLSQQKEKFEEQQQMLEIER--DQLREQIKNFTVQHEQS 790 Query: 1317 INQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILN---INEE 1373 I Q+ E++ K+ ++ Q +++ I I + Sbjct: 791 ILQLNEKEEEVDQFKLLLKQLTEEKEREAAKIKTQIQGMQNKIDQGRDELIKKENLIQDL 850 Query: 1374 NAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDE 1433 ++ N+AE K + + L+ ++ +K E I N + Sbjct: 851 RQEIYSKQSTIDSLQTTIGENQNEAEQKNQLIINSLK---QDLERKQKEVQIL----NTQ 903 Query: 1434 FENVRQQLVEYEKRIEDLTYEKESELAILRLKMHE-NANHYETMQKESEIERV-----KL 1487 FE +Q + E++++D+ KE E+ L ++++ N + KE+E++++ ++ Sbjct: 904 FEQFKQDSEDLEQQLQDMVKSKEDEITELNEQINKLNHQAITSQHKENELQKIQQEKDRI 963 Query: 1488 IEEL---NVKITESVSLNK---QVAELNKALEEEVAKTN-----EMQTALENQEIEIVTL 1536 ++L N KI E + + K + ++N L+ + + +Q + + EI +L Sbjct: 964 QDQLDLANKKIQEQIQIIKSFFKFYQINNRLKNNMQINSSYYDRNIQDVKDQHQKEISSL 1023 Query: 1537 NDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELL 1581 N++I+ Q M++ KI + + + EQLD + K +L Sbjct: 1024 NNQISEFQKMIKELQDKINSNEGQQNQENKQNQEQLDLEIEKNIL 1068 Score = 158 bits (384), Expect = 1e-36 Identities = 246/1273 (19%), Positives = 546/1273 (42%), Gaps = 79/1273 (6%) Query: 212 EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271 +D Q++ K Q++ ME ++E + ++IE + EE + L++ + + ++ Sbjct: 23 KDMTQKIEKFQQDSQEMEQMLEEEIKIKEEEIEKLQQELEEKEEEIQQLKSGQQDTGDQN 82 Query: 272 SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELL 331 KL + +Q ++KQ ++ E E K ++ ++ + +L Sbjct: 83 VKLEELEKQIEQNNEVISSLNDLISKQIFLVQHTQQKEQEYKDQIDNSSREIKNLQQQLK 142 Query: 332 E-HLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISR-KSGRNTASKMKSPWS-Q 388 E N + Q ++L+N+L + + + + + IS K N+ K S Q Sbjct: 143 EASKNVGVEQELEKLKNELKDSQSLLQKQKEENNQANQAISAMKEEINSKEKATESLSLQ 202 Query: 389 LSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTL 448 + + N +K + +I +LE I + N + + ++ + K+ Sbjct: 203 IKEQIQNSQKQEKELQIKIQQLESEIINSNAKKQEFKTLLESNNLQIQNNKSELQKKEEH 262 Query: 449 IAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSA 508 I LQ ++ Q + ++ T+ D ++ K+Q L+++ N+ + + + K Sbjct: 263 IHSLQEKYDQLLSQLQILQNDTSKSD--QLKKMQNLLEEKQNE------INKIQQDKKDL 314 Query: 509 EEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEE-LHHL 567 E ++ LN ID + + ++K+ + + Q I + S+ + NKEI++ EE + L Sbjct: 315 ETKVENLNKNIDNISIQLNELKNEFAQREQGYQSQISSQSQEAQKNKEIIQKKEEQIIEL 374 Query: 568 SQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQK---F 624 SQK +++ + LQ D + ++S +++K ++ E + + + ++ +K Sbjct: 375 SQKQIQIQNQLQVLQNDTSKSDQLKQVQSTLFEKENQLNQALEVQKELQAKIQDEKKLIE 434 Query: 625 DLVQELHILQQKYDEVEDKLADISQLQSDQV---CSEI--KSVHLEEQIDALSASKKELA 679 ++ +E L++ ++ E + +L+ ++ +EI K +E+ ++ + + +L Sbjct: 435 NIQKEADQLKKTLNDKEFNHKNSLELKDQEIQLKQAEIQKKEQQIEDLLNKQNQIQAQLL 494 Query: 680 LVIENLKLDK----EQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAE-KISE 734 +++L ++ +Q+ + +DLE ++ NK+ + Q+ DL ++ ++ E + + Sbjct: 495 KQLQHLLQERQDQIDQIQQSKRDLELQITNLNNKINQFEQKCKDLDLQINSLNQENQKKQ 554 Query: 735 LLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYS 794 + + N +E Q F ++Q+++ I+ ++E+ K + I L+ ++ + Sbjct: 555 VQIEENKKELENKQQIFKSQTELQQKE--IKESKAEIQKKQEIIQELQNKEKQLQSQ--- 609 Query: 795 LERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKK 854 L+ QL L+E+Q S+ + ++ RLA L + E + +E + K+L K Sbjct: 610 LQIMLQQLHKLLEERQNEISQVQENKKDIEQRLATL---TKDYETKQVEFDETKKQLSDK 666 Query: 855 NQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEH 914 Q +E Q L I + ++ L K + T + + + I+ E Sbjct: 667 EQQNKQEIQKLSIKVIGYEKDLTNLQSKCQSYYEENQQKTLKLKEYEKKVLDSQNISQEK 726 Query: 915 QTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENL 974 + + +K + L+ ++ Q+++ ++K L+++ EK E LE + + + I+N Sbjct: 727 ILKMEEIQKHCQQLQKQYEEQVQN---EQKKLSQQKEKFEEQQQMLEIERDQLREQIKNF 783 Query: 975 NMNVE----ELNKMNLELID-KHVQKQQTQSPDYTEQYI-NEINKLNALLKQKDEEIIAL 1028 + E +LN+ E+ K + KQ T+ + I +I + + Q +E+I Sbjct: 784 TVQHEQSILQLNEKEEEVDQFKLLLKQLTEEKEREAAKIKTQIQGMQNKIDQGRDELIKK 843 Query: 1029 NQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQ 1088 I + + S S +S TT EN E Q+ + KQ E Q V+ Sbjct: 844 ENLIQDLRQEIYSKQSTIDSLQ---TTIGENQNEAEQKNQLIINSLKQDLERKQKEVQIL 900 Query: 1089 DDQIKELKETKLTFEMNIPKTEGMIIS--STIEPMSDDANNVDXXXXXXXXXXXXL-KVQ 1145 + Q ++ K+ E + + M+ S I +++ N ++ L K+Q Sbjct: 901 NTQFEQFKQDSEDLEQQL---QDMVKSKEDEITELNEQINKLNHQAITSQHKENELQKIQ 957 Query: 1146 EEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETL---NTELTG--HDVVNQEQINQLK 1200 +E++ IQ++ L + + ++ + + K Q+ N ++ +D Q+ +Q + Sbjct: 958 QEKDRIQDQLDLANKKIQEQIQIIKSFFKFYQINNRLKNNMQINSSYYDRNIQDVKDQHQ 1017 Query: 1201 SKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQ 1260 ++ LN + + EL+ I+S Q+ E KQ+ Q + + +K Sbjct: 1018 KEISSLNNQISEFQKMIKELQDKINSNEGQQNQEN----KQNQEQLDLEIEKN------- 1066 Query: 1261 LSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQI 1320 E + E+L +++++ +E NKI + S +Q +++ L N K D + + Sbjct: 1067 -ILLECQIEELQNNIKNLQREANNKIEQFDNELSTV-LIQSQKQLLENSNLK--DKVQSL 1122 Query: 1321 E-ILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQ-SILNINEENAQLK 1378 E + + +D K +R ++Q ++++Q L +N + K Sbjct: 1123 EKRIGEQSKDYKNQNDRGKKISSDIQEKQSAQIREKDQEILKLKKQVHSLEDQVKNLEFK 1182 Query: 1379 -KSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDS-EIYQKTHEYTITLTQ--RNDEF 1434 K V A K LEL + ++++ + QK T L + ++ F Sbjct: 1183 IKKEQTNGSNSHQKQIEVYQANQKDLELKVEFLIEENRNLQQKLDAITEDLFEQLKDTRF 1242 Query: 1435 ENVRQ--QLVEYE 1445 N++Q Q++E E Sbjct: 1243 ANIQQLKQVIELE 1255 Score = 151 bits (365), Expect = 2e-34 Identities = 252/1264 (19%), Positives = 554/1264 (43%), Gaps = 113/1264 (8%) Query: 141 LGDVTHLSNTIKEKDNALS-VLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXX 199 L D+T ++ + +L+ ++KI E I LQ+++ EK++ I+ + K+ Sbjct: 22 LKDMTQKIEKFQQDSQEMEQMLEEEIKIKEEEIEKLQQELEEKEEEIQ-QLKSGQQDTGD 80 Query: 200 XXXXXXXXXXXXEDTKQQMTKM-----QENFIAMEAEWKDEKQRLLKDIESKDVR--ISS 252 E + ++ + ++ F+ + K+++ + D S++++ Sbjct: 81 QNVKLEELEKQIEQNNEVISSLNDLISKQIFLVQHTQQKEQEYKDQIDNSSREIKNLQQQ 140 Query: 253 LEEANK------LLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXL-----AKQSIE 301 L+EA+K LE + E+ S L ++ E+ + A +S+ Sbjct: 141 LKEASKNVGVEQELEKLKNELKDSQSLLQKQKEENNQANQAISAMKEEINSKEKATESLS 200 Query: 302 PSCEEKTEIEEKGSLEI-ANMTELTKKI----ELLEHLNCQIRQTNKELENKLATMGTES 356 +E+ + +K E+ + +L +I + + N +++N + + + Sbjct: 201 LQIKEQIQNSQKQEKELQIKIQQLESEIINSNAKKQEFKTLLESNNLQIQNNKSELQKKE 260 Query: 357 KAVSSPSKKGSPLISR-KSGRNTASKMKSPWSQLSS-ETLNQDTDKKINKNEIAK--LEM 412 + + S +K L+S+ + +N SK QL + L ++ +INK + K LE Sbjct: 261 EHIHSLQEKYDQLLSQLQILQNDTSKS----DQLKKMQNLLEEKQNEINKIQQDKKDLET 316 Query: 413 VIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNT 472 +++LNK++ + ++E G + I+ E Q++ E + Sbjct: 317 KVENLNKNIDNISIQLNE---LKNEFAQREQGYQSQISSQSQEAQKNKE-----IIQKKE 368 Query: 473 EDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSA-EEQITQLNDEIDAANKNMIKVKS 531 E + E+++ Q Q++ +L D + D +++++S E+ QLN ++ + K++ Sbjct: 369 EQIIELSQKQIQIQNQLQVLQNDTSKSDQLKQVQSTLFEKENQLNQALEVQKELQAKIQD 428 Query: 532 NHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSG 591 KL ++ +QK D K + + + + EL ++ + E +K Q+ + + Sbjct: 429 EKKL-IENIQKEADQLKKTLNDKEFNHKNSLELKDQEIQLKQAEIQKKEQQIEDL-LNKQ 486 Query: 592 RMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADIS-QL 650 I++ + K ++++L + R I ++ K DL ++ L K ++ E K D+ Q+ Sbjct: 487 NQIQAQLLK---QLQHLLQERQDQIDQIQQSKRDLELQITNLNNKINQFEQKCKDLDLQI 543 Query: 651 QSDQVCSEIKSVHLEEQIDALSAS----KKELALVIENLKLDKEQL---YGTIKDLENDK 703 S ++ K V +EE L K + L + +K K ++ I++L+N + Sbjct: 544 NSLNQENQKKQVQIEENKKELENKQQIFKSQTELQQKEIKESKAEIQKKQEIIQELQNKE 603 Query: 704 EDIMNKLQNYIQENMDLTDKLE------KMSAEKISELLAKINHEEQSKIQTQFGIDAKI 757 + + ++LQ +Q+ L ++ + + + + I + LA + + ++K Q +F + K Sbjct: 604 KQLQSQLQIMLQQLHKLLEERQNEISQVQENKKDIEQRLATLTKDYETK-QVEFD-ETKK 661 Query: 758 QERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYT 817 Q D +N + E+ K ++ E+ + ++ + S + Q L+E +K + Sbjct: 662 QLSDKEQQN-KQEIQKLSIKVIGYEKDLTNLQSKCQSYYEENQQKTLKLKEYEKKVLDSQ 720 Query: 818 IQEDELVNRLAVLMDHDRVVEKQLLE-IEHENKELQKKNQILLEENQNLQISLSDMQQHY 876 E + ++ + H + ++KQ E +++E K+L ++ + E+ Q L+I +++ Sbjct: 721 NISQEKILKMEEIQKHCQQLQKQYEEQVQNEQKKLSQQKEKFEEQQQMLEIERDQLREQI 780 Query: 877 NALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQI 936 + ++ L +E + Q + L LK++T E + + K +I+ ++ + + Sbjct: 781 KNFTVQHEQSILQLNEKEEEVDQFKLL---LKQLTEEKEREAAKIKTQIQGMQNKIDQGR 837 Query: 937 ESAIRDKKVL----NEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKH 992 + I+ + ++ E Y K + L+ + E +N E N + K +LE K Sbjct: 838 DELIKKENLIQDLRQEIYSKQ-STIDSLQTTIGENQNEAEQKNQLIINSLKQDLERKQKE 896 Query: 993 VQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQ 1052 VQ TQ + + + +L ++K K++EI LN++IN ++++ ++ S ++ Sbjct: 897 VQILNTQFEQFKQDSEDLEQQLQDMVKSKEDEITELNEQIN--KLNHQAITSQHKE---- 950 Query: 1053 FTTKLENMEEEMQRVSKQL-LDSKQHNEELQIL-----VREQDDQIK-ELKETKLTFEMN 1105 +L+ +++E R+ QL L +K+ E++QI+ + ++++K ++ ++ N Sbjct: 951 --NELQKIQQEKDRIQDQLDLANKKIQEQIQIIKSFFKFYQINNRLKNNMQINSSYYDRN 1008 Query: 1106 IPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLN 1165 I + I +++ + + Q+ +E Q + L + K Sbjct: 1009 IQDVKDQ-HQKEISSLNNQISEFQKMIKELQDKINSNEGQQNQENKQNQEQLDLEIEK-- 1065 Query: 1166 TELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLN---TENDNLLSTVAELRS 1222 L EC + +Q N + ++ + Q N+L + L Q EN NL V L Sbjct: 1066 NILLECQIEELQNNIKNLQREANNKIEQFD-NELSTVLIQSQKQLLENSNLKDKVQSLEK 1124 Query: 1223 SISSA------VDQRGFEI-AELWKQHLAQ-READ-----FQKTEHELRVQLSAFESKYE 1269 I + RG +I +++ ++ AQ RE D +K H L Q+ E K + Sbjct: 1125 RIGEQSKDYKNQNDRGKKISSDIQEKQSAQIREKDQEILKLKKQVHSLEDQVKNLEFKIK 1184 Query: 1270 QLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIED 1329 + + +S Q++ V L+ K++ E RNLQ+K D I E L +++D Sbjct: 1185 KEQTNGSNSHQKQIE--VYQANQKDLELKVEFLIEENRNLQQK-LDAIT--EDLFEQLKD 1239 Query: 1330 EKVA 1333 + A Sbjct: 1240 TRFA 1243 Score = 85.4 bits (202), Expect = 1e-14 Identities = 212/1035 (20%), Positives = 430/1035 (41%), Gaps = 110/1035 (10%) Query: 51 QIKFERAQKCLENAALVSKRIKEHRKATAELLGRPFVPGISESLANTLKQKEILMEKIKQ 110 + K E K ++N ++ +K + A E + + IS K KEI+ +K +Q Sbjct: 315 ETKVENLNKNIDNISIQLNELK-NEFAQRE---QGYQSQISSQSQEAQKNKEIIQKKEEQ 370 Query: 111 YKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNALS-VLQVKMKIME 169 ELS++ I QL V +T+ EK+N L+ L+V+ Sbjct: 371 IIELSQKQ---IQIQNQLQVLQNDTSKSDQLKQV---QSTLFEKENQLNQALEVQK---- 420 Query: 170 TTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAME 229 +LQ KI ++ ++IE K E + ++++ I ++ Sbjct: 421 ----ELQAKIQDEKKLIENIQK--------EADQLKKTLNDKEFNHKNSLELKDQEIQLK 468 Query: 230 AEWKDEKQRLLKDIESKDVRISS--LEEANKLLEAARFEI-SLEHSKLAQELEQXXXXXX 286 +K++ ++D+ +K +I + L++ LL+ + +I ++ SK EL+ Sbjct: 469 QAEIQKKEQQIEDLLNKQNQIQAQLLKQLQHLLQERQDQIDQIQQSKRDLELQITNLNNK 528 Query: 287 XXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELE 346 E C++ L+I ++ + +K ++ QI + KELE Sbjct: 529 I----------NQFEQKCKDL-------DLQINSLNQENQKKQV------QIEENKKELE 565 Query: 347 NKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKI--NK 404 NK ++++ K+ I +K + K Q + + Q K + + Sbjct: 566 NKQQIFKSQTELQQKEIKESKAEIQKKQEIIQELQNKEKQLQSQLQIMLQQLHKLLEERQ 625 Query: 405 NEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPS 464 NEI++++ NK +++ KD K ++ + +++Q ++ S Sbjct: 626 NEISQVQE-----NKKDIEQRLATLTKDYETKQVEFDETKKQ--LSDKEQQNKQEIQKLS 678 Query: 465 LIHVGTNTEDVNEIAKVQE----------QLKQELNDEIKDVNV-KDLIEKLKSAEEQIT 513 + +G + N +K Q +LK+ + N+ ++ I K++ ++ Sbjct: 679 IKVIGYEKDLTNLQSKCQSYYEENQQKTLKLKEYEKKVLDSQNISQEKILKMEEIQKHCQ 738 Query: 514 QLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAE 573 QL + + +N K S K K ++ Q+ ++ + ++I T + ++ E Sbjct: 739 QLQKQYEEQVQNEQKKLSQQKEKFEEQQQMLE--IERDQLREQIKNFTVQHEQSILQLNE 796 Query: 574 LEEEKGNLQLHLVDYDSGRMIESDVYKKMIE-MENLAETRLKAISLLESQKFDLVQELHI 632 EEE +L L + E+ K I+ M+N + + E+ DL QE++ Sbjct: 797 KEEEVDQFKLLLKQLTEEKEREAAKIKTQIQGMQNKIDQGRDELIKKENLIQDLRQEIYS 856 Query: 633 LQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQL 692 Q D ++ + + +Q +++Q +++ L++ ++ + L E K D E L Sbjct: 857 KQSTIDSLQTTIGE-NQNEAEQK-NQLIINSLKQDLERKQKEVQILNTQFEQFKQDSEDL 914 Query: 693 YGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFG 752 ++D+ KED + +L E ++ + S K +E L KI +E+ +IQ Q Sbjct: 915 EQQLQDMVKSKEDEITEL----NEQINKLNHQAITSQHKENE-LQKI-QQEKDRIQDQLD 968 Query: 753 I-DAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQK 811 + + KIQE+ I+ I+S Y+ RL+ ++ + + Y +R + + QK Sbjct: 969 LANKKIQEQ---IQIIKSFFKFYQIN-NRLKNNMQI--NSSY-YDRNIQDV---KDQHQK 1018 Query: 812 AYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSD 871 S Q E + L D E Q ENK+ Q++ + +E+N L+ + + Sbjct: 1019 EISSLNNQISEFQKMIKELQDKINSNEGQQ---NQENKQNQEQLDLEIEKNILLECQIEE 1075 Query: 872 MQQHYNALVEKA-NRTDLAESE--STKYQTQLRDLE-SNLKRITHEHQTLIVQKKKEIED 927 +Q + L +A N+ + ++E + Q+Q + LE SNLK + I ++ K+ ++ Sbjct: 1076 LQNNIKNLQREANNKIEQFDNELSTVLIQSQKQLLENSNLKDKVQSLEKRIGEQSKDYKN 1135 Query: 928 LEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLE 987 + + +I S I++K+ + EK+ E + +L+ Q+ ++ ++NL +++ Sbjct: 1136 -QNDRGKKISSDIQEKQSAQIR-EKDQE-ILKLKKQVHSLEDQVKNLEFKIKKEQTNGSN 1192 Query: 988 LIDKHVQKQQTQSPDY---TEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVS 1044 K ++ Q D E I E L L E++ + A + + V Sbjct: 1193 SHQKQIEVYQANQKDLELKVEFLIEENRNLQQKLDAITEDLFEQLKDTRFANIQQLKQVI 1252 Query: 1045 DYE--SKLAQFTTKL 1057 + E K F KL Sbjct: 1253 ELEIVKKTGSFGFKL 1267 >UniRef50_A2DKE3 Cluster: Viral A-type inclusion protein, putative; n=1; Trichomonas vaginalis G3|Rep: Viral A-type inclusion protein, putative - Trichomonas vaginalis G3 Length = 2870 Score = 186 bits (454), Expect = 3e-45 Identities = 295/1503 (19%), Positives = 645/1503 (42%), Gaps = 132/1503 (8%) Query: 143 DVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXX 202 +VT+L++ + + D S L ++ L++K++E IIE K Sbjct: 1230 EVTYLNDILNQLDIKNSDLAQQIAEHRQGYEILKQKLDEASHIIEEKESNVFEEKQQTNE 1289 Query: 203 XXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEA 262 ++++T+ + ++++ DE ++ L++ +++I E ++ Sbjct: 1290 VISQAKAKISRLERKLTESNSSNKDLQSK-VDELKKKLQESSENEIKIKQNTEQMRIEME 1348 Query: 263 ARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMT 322 R E +L ++L + L +++ S +++TE++ K + + Sbjct: 1349 KRIT---EQEQLKKQLTELQTNNINNQKQINDL-NNTLKISEKQRTELQVKFDEQTKSNK 1404 Query: 323 ELT-KKIELLEHLNCQIRQTNKELENKLAT---MGTESKAVSSPSKKGSPLISRKSGRNT 378 E+ +K + + LN +I + ++E + A + TE +++ K I + + T Sbjct: 1405 EIVDQKQQQIYSLNNEISKMKADIEKQNALNNDLNTEKSSLNVKIVKFESEIKSLNEKLT 1464 Query: 379 ASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEK--DTXXX 436 K SQL + L ++ ++ E++ L+ L +KE + ++ + Sbjct: 1465 NMKEIIANSQLEKKKLEEEIKSRVK--ELSNLQEENAKLLTSSHEKEITMQKEKFENETQ 1522 Query: 437 XXXXXXXGKDTLIAQLQ--LEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIK 494 K I++L+ L ++ L + + + ++ E+ +E + ++K Sbjct: 1523 KMKKEIEEKTANISELEKALSDKERNHKNLLSKIQKKYSQLEDKLEIAEEKLEESDKKVK 1582 Query: 495 DVNVKDLIEKLKSAEEQI-TQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDS 553 D+ K++I K + Q+ + N I+ NK + K+N L+LK ++ I+N + +S Sbjct: 1583 DL--KNIITLHKQNQVQMENEHNQLINDMNKQHDQEKNNLSLQLKSLENQIENLIQEKES 1640 Query: 554 NK-EIVRLTEELHHLSQKVAELEE--EKGNLQLHLVDYDSGRM---IESDVYKKMIEMEN 607 + EI + + + Q + + +K ++++ + ++ IES + +++ E EN Sbjct: 1641 YETEISTVYGDRDSMKQALEKASAFIQKKSIKIEKMKKQMSQVKVTIES-MNEELSEKEN 1699 Query: 608 LAETRLKAISLLESQKFDLVQE---LHILQQKYDEVEDKLADISQLQS--DQVCSEIKSV 662 E K + L QK + + + L + E + KL ++ L+ Q+ I+ + Sbjct: 1700 QIEELQKLTNRLGKQKVQITETNDAISKLNAEIAEKDQKLFEMEVLKKKISQLTETIEKL 1759 Query: 663 --HLEEQIDALSASKKELAL---VIENLKLDKEQLYGTIKDLEND-KEDIMNKLQNYIQE 716 LE + K EL +IE+LK KE + + DLE E+I LQ+ I E Sbjct: 1760 TKDLENSQNETINFKNELNYTKKLIEDLKQQKEDIQNEL-DLEKQHSEEISKTLQSKIDE 1818 Query: 717 NMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKS 776 N K+++++ + IS L K + + K+ +++ I+ ++ IE++++ L K Sbjct: 1819 NTSQNVKIQELNEKTIS--LQKESDSYKLKVDE---LNSDIKRKNAMIEDMKNHLISQKV 1873 Query: 777 RICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRV 836 + +S M+ + SL + + + + E Q+ ++ ++ + +L + +V Sbjct: 1874 ENETIYKSNNQMKAKIESLYNEIKENKAKIDEYQRESAKVDVERTQF--QLTIKDYEMKV 1931 Query: 837 VEKQLLEIEHENK--ELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESEST 894 ++ L + E K QK+N +L +E + + + Q ++ ++ + E Sbjct: 1932 KDENNLRLTTEEKLSNAQKENDLLKKEIEKKENDNQLLSQSKDSSLQTVTQLKSLVEEKE 1991 Query: 895 KYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQ---IESAIRDKKVLNEKYE 951 K L ++ + HE + + K EIED+ +T +++ DK L ++ Sbjct: 1992 KQIASLNKKVADYESTIHESEIYQTKTKLEIEDITKSKSTLQQLLDTISNDKSNLEKQIL 2051 Query: 952 KNIEYVTQLEAQLQEYKNNIENLNM----NVEELNKMNLELIDKHVQKQQTQSPDYTEQY 1007 V+ L AQ+ + + + L + N ++N +N + I + + QT+S + + + Sbjct: 2052 DQKSTVSLLTAQISNLQESEQKLKLTQIQNNTQINDLNNK-ISEMTKTDQTKS-EIIQNH 2109 Query: 1008 INEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVS----DYESK---LAQFTTKLENM 1060 N+I++L L K+ E+ N++I N + S++ + ++K L + TK ENM Sbjct: 2110 QNKIHELELQLLDKNNELNNANKEIENIKSQTESIIQKTAFEIQNKTEILNNYETKFENM 2169 Query: 1061 EEEMQRVSKQLLDSKQHNEELQILVREQDDQI--KELKETKLTFEMNIPKTEGMIISSTI 1118 +++ + + + D + + +L+ V ++Q+ ++K LT E+N + + I Sbjct: 2170 KKQNAKAAVTINDMTKSSSDLRKHVNLLENQLFDSKMKIENLTKELNESQNK-------I 2222 Query: 1119 EPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQL 1178 + M+ N + +++E +E + Q + K+ TE E +KI+ Sbjct: 2223 QSMTKQINE-SRAFSSTLQTKLDRESKQKESLQRELNFTQTELTKIQTEASEYKSKILHT 2281 Query: 1179 ETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAEL 1238 + + + N + + K K E+ N L T L ++S+ ++ E Sbjct: 2282 SEMESAMQ-----NSYSLIEEKLKSEENKRRNLERLITDMRLTRDVNSSPKKQEIE---- 2332 Query: 1239 WKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNK 1298 L++ L E++ ++L++ ++ T E N ++ ++++ L + Sbjct: 2333 -----------------SLKINLQNLENENDKLINEIK--TLNEKN-VLLQQEISKLSSD 2372 Query: 1299 LQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXX--------- 1349 LQ+KE+ ++L +K D+I++I L+++I+D K+ Sbjct: 2373 LQEKEKSEKSLLQKQNDLISEISKLKNDIKDHKINLSQSTSSLKKDISTKAKQIEQSKDE 2432 Query: 1350 -XDLRTENQSYK----------QMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDA 1398 +L+TEN S K Q E S+ N+ Q+K S +N Sbjct: 2433 LNNLQTENNSLKKKIQNLEAVLQDTEDSLAQSNQSQRQIKASYDLLNNKFEENQVLLNSK 2492 Query: 1399 EAKVLELTHQLELKDSEIYQKTHEYTITLTQR-NDEFENVRQQLVEYEKRIEDLTYEKES 1457 + ++ LT+++ K+ E+ +KT I + +R + + Q + E + ++E L E E Sbjct: 2493 QKEIERLTNEVSDKEKEL-EKTKSELINIQERIRSDSSKLNQDINEKQTKLESLNIELEK 2551 Query: 1458 ELAI---LRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEE 1514 I L K++ + +++ ++ + I + N + + L K L K LEE Sbjct: 2552 MRNINRELTSKVNSLTSQLQSIADSNQKDINTYISQYNEEKSTRKELEKSNETLKKKLEE 2611 Query: 1515 EVAKTNEMQTALENQEIEIVTLNDEITNLQNMV--RASSSKIQKHVSFAS----DTKQGR 1568 +V + + + + + I L E+T Q + + +QK V+ S D +Q Sbjct: 2612 KVKENKNLSVKITSLKTNIEELQIEVTRTQRTLVPKNQLESLQKSVNEMSRKLDDAQQNL 2671 Query: 1569 DEQ 1571 EQ Sbjct: 2672 AEQ 2674 Score = 166 bits (404), Expect = 4e-39 Identities = 281/1485 (18%), Positives = 637/1485 (42%), Gaps = 123/1485 (8%) Query: 147 LSNTIKEKDNALSVLQVKMK-IMETTILD--LQEKINEKDQIIEAKNKATTXXXXXXXXX 203 L N + ++ +S LQ ++K I + T L ++E+ E DQ+ + K T Sbjct: 658 LKNDNESANHTISALQEEIKKISDNTDLTRKIEEQEKEVDQLRKYNEKLETTISSSKQQK 717 Query: 204 XXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAA 263 + KQ + K+ + I+ A ++ + ++ + E KL EAA Sbjct: 718 EEMLHNQNKALKQMIFKLAKE-ISPNAVHSTSFNKMADEF---NMMSQTFNETMKLKEAA 773 Query: 264 RFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTE 323 ++ SK+ + A ++ + + +K ++AN TE Sbjct: 774 TNQLKRIDSKVYGITSRYNIETVDDTVK----ALTELDNLLNIEKQRTQKNLDDLANKTE 829 Query: 324 -LTKKIELLEHLNCQIRQTNKELENKLATM-GTES--KAVSSPSKKGSPLISRKSGRNTA 379 L +I+ L+ +N + NK+ + ++ + G E + ++ LI++ N Sbjct: 830 DLMDEIDSLQSVNVSLTDQNKKQQIEIIRLQGIERSVEGLNEDLNSAYQLINQYELANQN 889 Query: 380 SKMKSPWSQLSSETLNQDTDKKINK-----NEIAKLEMVIQSLNKDLVDKEYVISEKDTX 434 S+ + + +D K+I K NE+ ++ SL K + D I E + Sbjct: 890 SEYAQQMKFIKKKL--KDKQKQIQKYKSSVNELLDVQSENNSLKKQISDLNENIREMNGA 947 Query: 435 XXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTE-DVNEIAKVQEQLKQELNDEI 493 D L Q +LE + + SL+ + D + K ++LK+ N+E Sbjct: 948 LKAANKKLQSLDKL-HQRKLEMEDQIS--SLMTACRQLQMDKESLQKKVDELKKS-NEE- 1002 Query: 494 KDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKS----------NHKLKLKQMQKT 543 KD ++ +KL S + + Q I+ AN K + N ++++M+K Sbjct: 1003 KDDALESYRDKLNSQIDILGQSQSIIENANDKSRKDSNAIQELKEKLINSDKEIEKMKKE 1062 Query: 544 IDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMI 603 ++++ + SNKE L L QK+ E+ + H+ D+ + +D+ + Sbjct: 1063 MNDYENTNKSNKE------NLLKLQQKIIEVTRTVNPTENHVRVSDNVSQLLNDLDLIVK 1116 Query: 604 EMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVH 663 + +T + +++ + + L KL +S+ ++++ + + + Sbjct: 1117 AFSDKDKTINEIKGVIDKNNNEFISFKSNLSNIISSFSQKL--VSETDNNKLLN-LTNDF 1173 Query: 664 LEEQIDALSASKKELALVIEN-------LKLDKEQLYGTIKDLENDKEDIMNKLQNYIQE 716 ++ Q+D ++ K ++ +I+N L + +L ++++ ++ E NKL + + Sbjct: 1174 VKSQVDQINEIKSQIVQIIKNSSTYKPTLSSPQNELLDILREIISEHEVTENKLGSEVTY 1233 Query: 717 NMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAK--IQERDLYI----ENIESE 770 D+ ++L+ +++ +++ +A+ H + +I Q +A I+E++ + + Sbjct: 1234 LNDILNQLDIKNSD-LAQQIAE--HRQGYEILKQKLDEASHIIEEKESNVFEEKQQTNEV 1290 Query: 771 LSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVL 830 +S+ K++I RLE + L+ K D+L LQE + + +++ + Sbjct: 1291 ISQAKAKISRLERKLTESNSSNKDLQSKVDELKKKLQESSENEIKIKQNTEQMRIEMEKR 1350 Query: 831 MDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQIS---LSDMQQHYNALVEKANRTD 887 + ++KQL E++ N QK+ L N L+IS +++Q ++ K+N+ Sbjct: 1351 ITEQEQLKKQLTELQTNNINNQKQINDL---NNTLKISEKQRTELQVKFDEQT-KSNKEI 1406 Query: 888 LAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLN 947 + + + Y L + S +K + L E L ++ + ES I K LN Sbjct: 1407 VDQKQQQIYS--LNNEISKMKADIEKQNALNNDLNTEKSSLNVKI-VKFESEI---KSLN 1460 Query: 948 EKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQY 1007 EK E + + + ++ + I++ + L + N +L+ +K+ T E++ Sbjct: 1461 EKLTNMKEIIANSQLEKKKLEEEIKSRVKELSNLQEENAKLLTSSHEKEITMQK---EKF 1517 Query: 1008 INEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRV 1067 NE K+ +++K I L + +++ + ++ +++S + K +Q KLE EE+++ Sbjct: 1518 ENETQKMKKEIEEKTANISELEKALSDKERNHKNLLSKIQKKYSQLEDKLEIAEEKLEES 1577 Query: 1068 SKQLLDSKQ---HNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDD 1124 K++ D K +++ Q+ + + +Q+ + E N + + + IE + + Sbjct: 1578 DKKVKDLKNIITLHKQNQVQMENEHNQLINDMNKQHDQEKNNLSLQLKSLENQIENLIQE 1637 Query: 1125 ANNVDXXXXXXXXXXXXLK--VQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLN 1182 + + +K +++ FIQ++S+ E+ K ++++ + +E++N Sbjct: 1638 KESYETEISTVYGDRDSMKQALEKASAFIQKKSIKIEKMKKQMSQVK------VTIESMN 1691 Query: 1183 TELTGHDVVNQ-EQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQ 1241 EL+ + NQ E++ +L ++L + + +++L + I+ DQ+ FE+ E+ K+ Sbjct: 1692 EELSEKE--NQIEELQKLTNRLGKQKVQITETNDAISKLNAEIAEK-DQKLFEM-EVLKK 1747 Query: 1242 HLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIV--TMEQVTSLQNKL 1299 ++Q +K +L E+ + ++ + T K++ +Q +QN+L Sbjct: 1748 KISQLTETIEKLTKDL-------ENSQNETINF--KNELNYTKKLIEDLKQQKEDIQNEL 1798 Query: 1300 ----QDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTE 1355 Q EE + LQ K + +Q + E+ ++ ++ D++ + Sbjct: 1799 DLEKQHSEEISKTLQSKIDENTSQ-NVKIQELNEKTISLQKESDSYKLKVDELNSDIKRK 1857 Query: 1356 NQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSE 1415 N + M+ +++ EN + KS+ + + +AK+ E +Q E + Sbjct: 1858 NAMIEDMKNH-LISQKVENETIYKSNNQMKAKIESLYNEIKENKAKIDE--YQRESAKVD 1914 Query: 1416 IYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYET 1475 + ++T ++ +T+ + ++ + E+++ + +KE++L ++ EN N + Sbjct: 1915 V-ERT-QFQLTIKDYEMKVKDENNLRLTTEEKLSNA--QKENDLLKKEIEKKENDNQLLS 1970 Query: 1476 MQKESEIERVKLIEEL-NVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIV 1534 K+S ++ V ++ L K + SLNK+VA+ + E ++ + +T LE + +I Sbjct: 1971 QSKDSSLQTVTQLKSLVEEKEKQIASLNKKVADYESTIHE--SEIYQTKTKLEIE--DIT 2026 Query: 1535 TLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKE 1579 + L + + S ++K + T Q+ N E Sbjct: 2027 KSKSTLQQLLDTISNDKSNLEKQILDQKSTVSLLTAQISNLQESE 2071 Score = 165 bits (400), Expect = 1e-38 Identities = 300/1576 (19%), Positives = 661/1576 (41%), Gaps = 138/1576 (8%) Query: 90 ISESLANTLKQKEILMEKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSN 149 + E L N+ K+ E + +++ Y+ +K + +++ V N Sbjct: 1045 LKEKLINSDKEIEKMKKEMNDYENTNKSNKENLLKLQQKIIEVTRT--------VNPTEN 1096 Query: 150 TIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKA--TTXXXXXXXXXXXXX 207 ++ DN +L + ++ D + INE +I+ N + Sbjct: 1097 HVRVSDNVSQLLN-DLDLIVKAFSDKDKTINEIKGVIDKNNNEFISFKSNLSNIISSFSQ 1155 Query: 208 XXXXEDTKQQMTKMQENFIAMEAEWKDE-KQRLLKDIESKDVRISSLEEA-NKLLEAARF 265 E ++ + +F+ + + +E K ++++ I++ +L N+LL+ R Sbjct: 1156 KLVSETDNNKLLNLTNDFVKSQVDQINEIKSQIVQIIKNSSTYKPTLSSPQNELLDILR- 1214 Query: 266 EISLEH----SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEE---KTEIEEKGSLEI 318 EI EH +KL E+ LA+Q E K +++E + Sbjct: 1215 EIISEHEVTENKLGSEVTYLNDILNQLDIKNSDLAQQIAEHRQGYEILKQKLDEASHIIE 1274 Query: 319 ANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNT 378 + + ++ + + Q + LE KL + +K + S + + S Sbjct: 1275 EKESNVFEEKQQTNEVISQAKAKISRLERKLTESNSSNKDLQSKVDELKKKLQESSENEI 1334 Query: 379 ASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYV--ISEKDTXXX 436 K+K Q+ E + T+++ K ++ +L+ + K + D ISEK Sbjct: 1335 --KIKQNTEQMRIEMEKRITEQEQLKKQLTELQTNNINNQKQINDLNNTLKISEKQRTEL 1392 Query: 437 XXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQ--LKQELNDEIK 494 K + ++ Q+ + SL N E A +++Q L +LN E Sbjct: 1393 QVKFDEQTK----SNKEIVDQKQQQIYSL-----NNEISKMKADIEKQNALNNDLNTEKS 1443 Query: 495 DVNVK--DLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKV-- 550 +NVK ++KS E++T + + I + K++ K ++K++ + +K+ Sbjct: 1444 SLNVKIVKFESEIKSLNEKLTNMKEIIANSQLEKKKLEEEIKSRVKELSNLQEENAKLLT 1503 Query: 551 SDSNKEIVRLTEELHHLSQKVA-ELEEEKGN---LQLHLVDYDSG-RMIESDVYKKMIEM 605 S KEI E+ + +QK+ E+EE+ N L+ L D + + + S + KK ++ Sbjct: 1504 SSHEKEITMQKEKFENETQKMKKEIEEKTANISELEKALSDKERNHKNLLSKIQKKYSQL 1563 Query: 606 ENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLE 665 E+ E + + + + DL + + +Q ++E+ + +Q+ +++ H + Sbjct: 1564 EDKLEIAEEKLEESDKKVKDLKNIITLHKQNQVQMEN--------EHNQLINDMNKQHDQ 1615 Query: 666 EQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQN---YIQENMDLTD 722 E+ + LS K L IENL +KE I + D++ + L+ +IQ+ + Sbjct: 1616 EK-NNLSLQLKSLENQIENLIQEKESYETEISTVYGDRDSMKQALEKASAFIQKKSIKIE 1674 Query: 723 KLEK-MSAEKIS-ELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICR 780 K++K MS K++ E + + E++++I+ + ++ ++ + I +SK + I Sbjct: 1675 KMKKQMSQVKVTIESMNEELSEKENQIEELQKLTNRLGKQKVQITETNDAISKLNAEIAE 1734 Query: 781 LEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQ 840 ++ + ME L++K QL +++ K ++E +N L +++E Sbjct: 1735 KDQKLFEME----VLKKKISQLTETIEKLTKDLEN---SQNETINFKNELNYTKKLIEDL 1787 Query: 841 LLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQL 900 + E EL + Q E ++ LQ + + + E +T + ES Y+ ++ Sbjct: 1788 KQQKEDIQNELDLEKQHSEEISKTLQSKIDENTSQNVKIQELNEKTISLQKESDSYKLKV 1847 Query: 901 RDLESNLKR---ITHEHQTLIVQKKKEIEDL---EIEFNTQIESA---IRDKKVLNEKYE 951 +L S++KR + + + ++ +K E E + + +IES I++ K ++Y+ Sbjct: 1848 DELNSDIKRKNAMIEDMKNHLISQKVENETIYKSNNQMKAKIESLYNEIKENKAKIDEYQ 1907 Query: 952 KNIEYV----TQLEAQLQEYKNNIE---NLNMNVEE-LNKMNLE--LIDKHVQKQQTQSP 1001 + V TQ + +++Y+ ++ NL + EE L+ E L+ K ++K++ + Sbjct: 1908 RESAKVDVERTQFQLTIKDYEMKVKDENNLRLTTEEKLSNAQKENDLLKKEIEKKENDNQ 1967 Query: 1002 ---DYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLE 1058 + + + +L +L+++K+++I +LN+K+ Y S + +ES++ Q TKLE Sbjct: 1968 LLSQSKDSSLQTVTQLKSLVEEKEKQIASLNKKV----ADYESTI--HESEIYQTKTKLE 2021 Query: 1059 NME-EEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETK--LTFEM-NIPKTEGMII 1114 + + + +QLLD+ +++ + QI + K T LT ++ N+ ++E + Sbjct: 2022 IEDITKSKSTLQQLLDTISNDKS------NLEKQILDQKSTVSLLTAQISNLQESEQKLK 2075 Query: 1115 SSTIEPMS--DDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSV-LQEQSAKLNTELQEC 1171 + I+ + +D NN + +Q + I E + L +++ +LN +E Sbjct: 2076 LTQIQNNTQINDLNNKISEMTKTDQTKSEI-IQNHQNKIHELELQLLDKNNELNNANKEI 2134 Query: 1172 YTKIIQLETLNTELTGHDVVNQEQI-NQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQ 1230 Q E++ + T ++ N+ +I N ++K E + +N T+ ++ S S D Sbjct: 2135 ENIKSQTESI-IQKTAFEIQNKTEILNNYETKFENMKKQNAKAAVTINDMTKSSS---DL 2190 Query: 1231 RGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTME 1290 R + L + L + + EL + +S +Q+ +S S+ +T + Sbjct: 2191 R--KHVNLLENQLFDSKMKIENLTKELNESQNKIQSMTKQINESRAFSSTLQTKLDRESK 2248 Query: 1291 QVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXX 1350 Q SLQ +L + L +Q + ++ ++I + SE+E Sbjct: 2249 QKESLQRELNFTQTELTKIQTEASEYKSKI-LHTSEMESAMQNSYSLIEEKLKSEENKRR 2307 Query: 1351 DLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLE 1410 +L + ++ + +E LK + + K + L ++ Sbjct: 2308 NLERLITDMRLTRDVNSSPKKQEIESLKINLQNLENENDKLINEIKTLNEKNVLLQQEIS 2367 Query: 1411 LKDSEIYQKTHEYTITLTQRND---EFENVRQQLVEYEKRIEDLTYEKESELAILRLKMH 1467 S++ +K L ++ND E ++ + +++ + T + +++ ++ Sbjct: 2368 KLSSDLQEKEKSEKSLLQKQNDLISEISKLKNDIKDHKINLSQSTSSLKKDISTKAKQIE 2427 Query: 1468 ENANHYETMQKESEIERVKL------IEELNVKITESVSLNKQVAE----LNKALEEEVA 1517 ++ + +Q E+ + K+ +++ + +S +Q+ LN EE Sbjct: 2428 QSKDELNNLQTENNSLKKKIQNLEAVLQDTEDSLAQSNQSQRQIKASYDLLNNKFEENQV 2487 Query: 1518 KTNEMQTALE-------NQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDE 1570 N Q +E ++E E+ E+ N+Q +R+ SSK+ + ++ + + Sbjct: 2488 LLNSKQKEIERLTNEVSDKEKELEKTKSELINIQERIRSDSSKLNQDINEKQTKLESLNI 2547 Query: 1571 QLD--NTMNKELLDAV 1584 +L+ +N+EL V Sbjct: 2548 ELEKMRNINRELTSKV 2563 Score = 156 bits (379), Expect = 4e-36 Identities = 284/1453 (19%), Positives = 599/1453 (41%), Gaps = 115/1453 (7%) Query: 149 NTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXX 208 N+ KE + ++ + TIL LQ+ N+KDQ + K Sbjct: 525 NSFKENQEKFRISLME-NVTNQTILPLQQSNNDKDQ--QIKELMNQIKLIKDKQDEVESK 581 Query: 209 XXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEIS 268 +D QQM K+ + +E E K K L ++D + ++A ++ Sbjct: 582 NKAKD--QQMKKLIKE---LEKEQKKNKDLTLTIANAEDPK-----HIQTQMQARIDDLQ 631 Query: 269 LEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKI 328 E S L QE++Q L K E + + ++E+ +I++ T+LT+KI Sbjct: 632 SEISNLKQEIQQNEQKYQNLKKENKSL-KNDNESANHTISALQEE-IKKISDNTDLTRKI 689 Query: 329 ELLEHLNCQIRQTNKELENKLATMGTE-SKAVSSPSKKGSPLISRKSGRNTASKMKSPWS 387 E E Q+R+ N++LE +++ + + + + +K +I + + + + + S Sbjct: 690 EEQEKEVDQLRKYNEKLETTISSSKQQKEEMLHNQNKALKQMIFKLAKEISPNAVHSTSF 749 Query: 388 QLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDT 447 ++ N + NE KL+ + K + K Y I+ + + Sbjct: 750 NKMADEFNMMSQ---TFNETMKLKEAATNQLKRIDSKVYGITSRYNIETVDDTVKALTE- 805 Query: 448 LIAQLQLEHQQHMEGPSLIHVGTNTED-VNEIAKVQEQLKQELNDEIKDVNVKDLIE--K 504 L L +E Q+ + +L + TED ++EI + Q +N + D N K IE + Sbjct: 806 LDNLLNIEKQRTQK--NLDDLANKTEDLMDEIDSL-----QSVNVSLTDQNKKQQIEIIR 858 Query: 505 LKSAEEQITQLNDEIDAANK--NMIKVKSNH----------KLKLKQMQKTIDNFSKVSD 552 L+ E + LN+++++A + N ++ + + K KLK QK I K Sbjct: 859 LQGIERSVEGLNEDLNSAYQLINQYELANQNSEYAQQMKFIKKKLKDKQKQI---QKYKS 915 Query: 553 SNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETR 612 S E++ + E + L +++++L E + L + ++++ +EME+ + Sbjct: 916 SVNELLDVQSENNSLKKQISDLNENIREMNGALKAANKKLQSLDKLHQRKLEMEDQISSL 975 Query: 613 LKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALS 672 + A L+ K L +++ L++ +E +D L + Q+ +S + E +A Sbjct: 976 MTACRQLQMDKESLQKKVDELKKSNEEKDDALESYRDKLNSQIDILGQSQSIIE--NAND 1033 Query: 673 ASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKI 732 S+K+ + I+ L KE+L + K++E K++ MN +N + N + KL++ E Sbjct: 1034 KSRKD-SNAIQEL---KEKLINSDKEIEKMKKE-MNDYENTNKSNKENLLKLQQKIIEVT 1088 Query: 733 SELLAKINH----EEQSKIQTQFGIDAK-IQERDLYIENIESELSKYKSRICRLEESIA- 786 + NH + S++ + K ++D I I+ + K + + +++ Sbjct: 1089 RTVNPTENHVRVSDNVSQLLNDLDLIVKAFSDKDKTINEIKGVIDKNNNEFISFKSNLSN 1148 Query: 787 VMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEH 846 ++ L + D L Q +E+ +++ ++ + + L ++ Sbjct: 1149 IISSFSQKLVSETDN-NKLLNLTNDFVKSQVDQINEIKSQIVQIIKNSSTYKPTLSSPQN 1207 Query: 847 ENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKAN--RTDLAE--SESTKYQTQLRD 902 E ++ ++ ++ E++ + L + N ++ + + +DLA+ +E + L+ Sbjct: 1208 ELLDILRE---IISEHEVTENKLGSEVTYLNDILNQLDIKNSDLAQQIAEHRQGYEILKQ 1264 Query: 903 LESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEA 962 I E ++ + ++K++ ++ + +I R N + V +L+ Sbjct: 1265 KLDEASHIIEEKESNVFEEKQQTNEVISQAKAKISRLERKLTESNSSNKDLQSKVDELKK 1324 Query: 963 QLQEYKNNIENLNMNVEELN-KMNLELID-KHVQKQQTQSPDYTEQYINEINKLNALLKQ 1020 +LQE N + N E++ +M + + + ++KQ T+ +IN LN LK Sbjct: 1325 KLQESSENEIKIKQNTEQMRIEMEKRITEQEQLKKQLTELQTNNINNQKQINDLNNTLKI 1384 Query: 1021 KDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEE 1080 +++ L K + S +V + ++ ++ M+ ++++ + D Sbjct: 1385 SEKQRTELQVKFDEQTKSNKEIVDQKQQQIYSLNNEISKMKADIEKQNALNNDLNTEKSS 1444 Query: 1081 LQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXX 1140 L + + + + +IK L E KLT M + +E + + V Sbjct: 1445 LNVKIVKFESEIKSLNE-KLT-NMKEIIANSQLEKKKLE--EEIKSRVKELSNLQEENAK 1500 Query: 1141 XLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLK 1200 L E+E ++ + ++ K+ E++E K + L L+ + ++ +++++ Sbjct: 1501 LLTSSHEKEITMQKEKFENETQKMKKEIEE---KTANISELEKALSDKERNHKNLLSKIQ 1557 Query: 1201 SKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQ 1260 K QL D L +L S D + I L KQ+ Q E EH Sbjct: 1558 KKYSQL---EDKLEIAEEKLEESDKKVKDLK--NIITLHKQNQVQME-----NEHN---- 1603 Query: 1261 LSAFESKYEQLLDSVQSSTQEETNKIVTMEQV-TSLQNKLQDKEEHLRNLQEKYADVINQ 1319 + + D + QE+ N + ++ + ++N +Q+KE + + Y D + Sbjct: 1604 --------QLINDMNKQHDQEKNNLSLQLKSLENQIENLIQEKESYETEISTVYGDRDSM 1655 Query: 1320 IEIL-RSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLK 1378 + L ++ +K + + E S K+ Q + + + + K Sbjct: 1656 KQALEKASAFIQKKSIKIEKMKKQMSQVKVTIESMNEELSEKENQIEELQKLTNRLGKQK 1715 Query: 1379 KSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVR 1438 + + + K+ E+ L+ K S++ + + T L +E N + Sbjct: 1716 VQITETNDAISKLNAEIAEKDQKLFEM-EVLKKKISQLTETIEKLTKDLENSQNETINFK 1774 Query: 1439 QQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQK---ESEIERVKLIEELNVKI 1495 +L +K IEDL +KE L L+ + +T+Q E+ + VK I+ELN K Sbjct: 1775 NELNYTKKLIEDLKQQKEDIQNELDLEKQHSEEISKTLQSKIDENTSQNVK-IQELNEKT 1833 Query: 1496 ----TESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTL---NDE----ITNLQ 1544 ES S +V ELN ++ + A +M+ L +Q++E T+ N++ I +L Sbjct: 1834 ISLQKESDSYKLKVDELNSDIKRKNAMIEDMKNHLISQKVENETIYKSNNQMKAKIESLY 1893 Query: 1545 NMVRASSSKIQKH 1557 N ++ + +KI ++ Sbjct: 1894 NEIKENKAKIDEY 1906 Score = 151 bits (366), Expect = 2e-34 Identities = 238/1220 (19%), Positives = 530/1220 (43%), Gaps = 99/1220 (8%) Query: 415 QSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTED 474 Q N+ + + IS + + + +L+ + Q+ E I + NTE Sbjct: 1285 QQTNEVISQAKAKISRLERKLTESNSSNKDLQSKVDELKKKLQESSENE--IKIKQNTEQ 1342 Query: 475 VN-EIAK---VQEQLKQELND-EIKDVN----VKDLIEKLKSAEEQITQLN---DEIDAA 522 + E+ K QEQLK++L + + ++N + DL LK +E+Q T+L DE + Sbjct: 1343 MRIEMEKRITEQEQLKKQLTELQTNNINNQKQINDLNNTLKISEKQRTELQVKFDEQTKS 1402 Query: 523 NKNMIKVK-------SNHKLKLK---QMQKTIDNF--SKVSDSNKEIVRLTEELHHLSQK 570 NK ++ K +N K+K + Q ++N ++ S N +IV+ E+ L++K Sbjct: 1403 NKEIVDQKQQQIYSLNNEISKMKADIEKQNALNNDLNTEKSSLNVKIVKFESEIKSLNEK 1462 Query: 571 VAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQEL 630 + ++E N QL + +E ++ ++ E+ NL E K ++ ++ + +E Sbjct: 1463 LTNMKEIIANSQLEK------KKLEEEIKSRVKELSNLQEENAKLLTSSHEKEITMQKEK 1516 Query: 631 --HILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLD 688 + Q+ E+E+K A+IS+L+ + S+ + H + LS +K+ + + + L++ Sbjct: 1517 FENETQKMKKEIEEKTANISELE--KALSDKERNHK----NLLSKIQKKYSQLEDKLEIA 1570 Query: 689 KEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQ 748 +E+L + K +++ K I QN +Q + + M+ + E K N Q K Sbjct: 1571 EEKLEESDKKVKDLKNIITLHKQNQVQMENEHNQLINDMNKQHDQE---KNNLSLQLK-S 1626 Query: 749 TQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQE 808 + I+ IQE++ Y I + S LE++ A ++ + +E+ Q+ S ++ Sbjct: 1627 LENQIENLIQEKESYETEISTVYGDRDSMKQALEKASAFIQKKSIKIEKMKKQM-SQVKV 1685 Query: 809 KQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQIS 868 ++ +E +++ + L L + + KQ ++I N + K N + E++Q L Sbjct: 1686 TIESMNEELSEKENQIEELQKLTNR---LGKQKVQITETNDAISKLNAEIAEKDQKL-FE 1741 Query: 869 LSDMQQHYNALVEKANRT--DL--AESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKE 924 + +++ + L E + DL +++E+ ++ +L + ++ + + + + + E Sbjct: 1742 MEVLKKKISQLTETIEKLTKDLENSQNETINFKNELNYTKKLIEDLKQQKEDIQNELDLE 1801 Query: 925 IEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKM 984 + E E + ++S I + N K ++ E L+ + YK ++ LN +++ N M Sbjct: 1802 KQHSE-EISKTLQSKIDENTSQNVKIQELNEKTISLQKESDSYKLKVDELNSDIKRKNAM 1860 Query: 985 NLELIDKHVQKQQTQSPDYTEQYINEINKLNALL------KQKDEEIIALNQKINNAQVS 1038 +E + H+ Q+ ++ + K+ +L K K +E + K++ + Sbjct: 1861 -IEDMKNHLISQKVENETIYKSNNQMKAKIESLYNEIKENKAKIDEYQRESAKVDVERTQ 1919 Query: 1039 YMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKET 1098 + + DYE K+ EE++ K+ K+ E+ +E D+Q+ L ++ Sbjct: 1920 FQLTIKDYEMKVKDENNLRLTTEEKLSNAQKENDLLKKEIEK-----KENDNQL--LSQS 1972 Query: 1099 KLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEE-EEFIQERSVL 1157 K + + + + ++ + S + D K + E E+ + +S L Sbjct: 1973 KDSSLQTVTQLKSLVEEKEKQIASLNKKVADYESTIHESEIYQTKTKLEIEDITKSKSTL 2032 Query: 1158 QEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTV 1217 Q+ ++ + +I+ ++ + LT QE +LK Q NT+ ++L + + Sbjct: 2033 QQLLDTISNDKSNLEKQILDQKSTVSLLTAQISNLQESEQKLKLTQIQNNTQINDLNNKI 2092 Query: 1218 AELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQS 1277 +E+ + DQ EI + + + + E +EL E+ Q +Q Sbjct: 2093 SEMTKT-----DQTKSEIIQNHQNKIHELELQLLDKNNELNNANKEIENIKSQTESIIQK 2147 Query: 1278 STQEETNKIVTMEQV-TSLQN-KLQDKEEH--LRNLQEKYADVINQIEILRSEIEDEKVA 1333 + E NK + T +N K Q+ + + ++ + +D+ + +L +++ D K+ Sbjct: 2148 TAFEIQNKTEILNNYETKFENMKKQNAKAAVTINDMTKSSSDLRKHVNLLENQLFDSKMK 2207 Query: 1334 FXXXXXXXXXXXXXXXXDLRTENQS--YKQMQEQSILNINEENAQLKKSSXXXXXXXXXX 1391 + N+S + + + +++ L++ Sbjct: 2208 IENLTKELNESQNKIQSMTKQINESRAFSSTLQTKLDRESKQKESLQRELNFTQTELTKI 2267 Query: 1392 XXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDL 1451 ++ ++K+L H E++ + + Y++ + E EN R+ L E+ I D+ Sbjct: 2268 QTEASEYKSKIL---HTSEMESA----MQNSYSLIEEKLKSE-ENKRRNL---ERLITDM 2316 Query: 1452 TYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKA 1511 ++ + + ++ + + ++ E++ KLI E+ ++V L +++++L+ Sbjct: 2317 RLTRDVNSSPKKQEIESLKINLQNLENEND----KLINEIKTLNEKNVLLQQEISKLSSD 2372 Query: 1512 LEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSF-ASDTKQGRDE 1570 L+E+ + + EI L ++I + + + S+S ++K +S A +Q +DE Sbjct: 2373 LQEKEKSEKSLLQKQNDLISEISKLKNDIKDHKINLSQSTSSLKKDISTKAKQIEQSKDE 2432 Query: 1571 QLDN--TMNKELLDAVPRAE 1588 L+N T N L + E Sbjct: 2433 -LNNLQTENNSLKKKIQNLE 2451 Score = 134 bits (325), Expect = 1e-29 Identities = 203/998 (20%), Positives = 417/998 (41%), Gaps = 71/998 (7%) Query: 144 VTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXX 203 ++ L+ I EKD L +M++++ I L E I + + +E T Sbjct: 1725 ISKLNAEIAEKDQKL----FEMEVLKKKISQLTETIEKLTKDLENSQNETINFKNELNYT 1780 Query: 204 XXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLK----DIESKDVRISSLEEANKL 259 ED KQQ +Q N + +E + +E + L+ + S++V+I L E Sbjct: 1781 KKLI----EDLKQQKEDIQ-NELDLEKQHSEEISKTLQSKIDENTSQNVKIQELNEKTIS 1835 Query: 260 LEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIA 319 L+ L+ +L ++++ L Q +E K+ + K +E Sbjct: 1836 LQKESDSYKLKVDELNSDIKRKNAMIEDMKNH---LISQKVENETIYKSNNQMKAKIESL 1892 Query: 320 --NMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRN 377 + E KI+ + + ++ + + + + K ++ +S N Sbjct: 1893 YNEIKENKAKIDEYQRESAKVDVERTQFQLTIKDYEMKVKDENNLRLTTEEKLSNAQKEN 1952 Query: 378 TASKMKSPWSQLSSETLNQDTDKKIN-----KNEIAKLEMVIQSLNKDLVDKEYVISEKD 432 K + + ++ L+Q D + K+ + + E I SLNK + D E I E + Sbjct: 1953 DLLKKEIEKKENDNQLLSQSKDSSLQTVTQLKSLVEEKEKQIASLNKKVADYESTIHESE 2012 Query: 433 TXXXXXXXX----XXGKDTLIAQLQL--EHQQHMEGPSLIHVGTNTEDVNEIAKVQE-QL 485 K TL L + ++E L T + +I+ +QE + Sbjct: 2013 IYQTKTKLEIEDITKSKSTLQQLLDTISNDKSNLEKQILDQKSTVSLLTAQISNLQESEQ 2072 Query: 486 KQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTID 545 K +L + + DL K+ S + Q EI ++N I H+L+L+ + K Sbjct: 2073 KLKLTQIQNNTQINDLNNKI-SEMTKTDQTKSEIIQNHQNKI-----HELELQLLDKN-- 2124 Query: 546 NFSKVSDSNKEIVRLTEELHHLSQKVA-ELEEEKGNLQLHLVDYDSGRMIESDVYKKMIE 604 ++++++NKEI + + + QK A E++ + L + +++ + + + + Sbjct: 2125 --NELNNANKEIENIKSQTESIIQKTAFEIQNKTEILNNYETKFENMKKQNAKAAVTIND 2182 Query: 605 MENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADIS-QLQSDQVCSEIKSVH 663 M + K ++LLE+Q FD ++ L ++ +E ++K+ ++ Q+ + S Sbjct: 2183 MTKSSSDLRKHVNLLENQLFDSKMKIENLTKELNESQNKIQSMTKQINESRAFSSTLQTK 2242 Query: 664 LEEQIDALSASKKELALVIENL-KLDKEQLYGTIKDLE-NDKEDIMNKLQNYIQENMDLT 721 L+ + + ++EL L K+ E K L ++ E M + I+E + Sbjct: 2243 LDRESKQKESLQRELNFTQTELTKIQTEASEYKSKILHTSEMESAMQNSYSLIEEKLKSE 2302 Query: 722 DKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRL 781 + + I+++ ++ + S + Q +I+ + ++N+E+E K L Sbjct: 2303 ENKRRNLERLITDM--RLTRDVNSSPKKQ-----EIESLKINLQNLENENDK-------L 2348 Query: 782 EESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLM----DHDRVV 837 I + ++ L+++ +L S LQEK+K+ ++++L++ ++ L DH + Sbjct: 2349 INEIKTLNEKNVLLQQEISKLSSDLQEKEKSEKSLLQKQNDLISEISKLKNDIKDHKINL 2408 Query: 838 EKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQ 897 + ++ + K+ + +E NLQ + +++ L T+ + ++S + Q Sbjct: 2409 SQSTSSLKKDISTKAKQIEQSKDELNNLQTENNSLKKKIQNLEAVLQDTEDSLAQSNQSQ 2468 Query: 898 TQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYV 957 Q++ L E+Q L+ K+KEIE L E + + + + K L E+ Sbjct: 2469 RQIKASYDLLNNKFEENQVLLNSKQKEIERLTNEVSDKEKELEKTKSELINIQERIRSDS 2528 Query: 958 TQLEAQLQEYKNNIENLNMNVEELNKMNLELIDK-HVQKQQTQS-PDYTEQYINE-INKL 1014 ++L + E + +E+LN+ +E++ +N EL K + Q QS D ++ IN I++ Sbjct: 2529 SKLNQDINEKQTKLESLNIELEKMRNINRELTSKVNSLTSQLQSIADSNQKDINTYISQY 2588 Query: 1015 NALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDS 1074 N K +E+ N+ + + + K+ T +E ++ E+ R + L+ Sbjct: 2589 NE-EKSTRKELEKSNETLKKKLEEKVKENKNLSVKITSLKTNIEELQIEVTRTQRTLV-P 2646 Query: 1075 KQHNEELQILVREQ----DDQIKELKETKLTFEMNIPK 1108 K E LQ V E DD + L E K + I K Sbjct: 2647 KNQLESLQKSVNEMSRKLDDAQQNLAEQKSRYSSIIEK 2684 Score = 126 bits (305), Expect = 4e-27 Identities = 281/1526 (18%), Positives = 637/1526 (41%), Gaps = 147/1526 (9%) Query: 168 METTILDLQEKINEKDQIIEA--KNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENF 225 +E DLQ++I++ +EA +N + + QQ T+ + Sbjct: 203 LEQKNADLQDEISQLQSKLEAASRNAVDSEEMQNQNSQVQQEILILKQKLQQQTETLNQY 262 Query: 226 IAMEAEWKDEKQRLLKDIESKDVR-ISSLEEANKLLEAARFEISLEHSKLAQELEQXXXX 284 + +++ L + ++ +++ ++ + L+ R + E++KL + + Q Sbjct: 263 VVDITNERNKNNELEQQLQELHFNGVANPQQYAQDLDELR-NVKSENTKLNERISQLQMI 321 Query: 285 XXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKE 344 L KQ I+ E+ ++ + N+ E+++ I L+ N + + Sbjct: 322 NDENESKIQNLVKQ-IQEKDEKYGDVAQSLEERQNNLKEMSENIIKLQSENSALTKERNS 380 Query: 345 LENKLA--TMGT-ESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDK- 400 L ++L TM E ++ ++ S + R ++T + Q +N + ++ Sbjct: 381 LSSELQQKTMFIDELQSNLKQVEEKSRTVYRSGNKSTIVDDRVKTLQERFNAVNSEKEEL 440 Query: 401 KINKNEIAKL----EMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEH 456 K+ +++ +L + I L K+ + + I+EK T+I ++Q E+ Sbjct: 441 KLTLDQVKQLVTDQQRQILQLKKENSELKQNINEK-----TDEDDSFNLSTMINKMQKEN 495 Query: 457 QQHMEG--PSLIHVGTNTE--------DVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLK 506 + ++ S+ + + N + QE+ + L + + + + L + Sbjct: 496 SEDIDKLHKSITELQNQVQYWKEKCLSQENSFKENQEKFRISLMENVTNQTILPLQQSNN 555 Query: 507 SAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEI---VRLTEE 563 ++QI +L ++I +V+S +K K +QM+K I K NK++ + E+ Sbjct: 556 DKDQQIKELMNQIKLIKDKQDEVESKNKAKDQQMKKLIKELEKEQKKNKDLTLTIANAED 615 Query: 564 LHHL-SQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQ 622 H+ +Q A +++ + + + ++ K+ ++N E+ IS L+ + Sbjct: 616 PKHIQTQMQARIDDLQSEISNLKQEIQQNEQKYQNLKKENKSLKNDNESANHTISALQ-E 674 Query: 623 KFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVI 682 + + + L +K +E ++K D + ++++ + I S +++ + L K L +I Sbjct: 675 EIKKISDNTDLTRKIEE-QEKEVDQLRKYNEKLETTISSSKQQKE-EMLHNQNKALKQMI 732 Query: 683 ENLKLDKEQLYGTIKDLE-NDKEDIMNKLQNYIQENMDL----TDKLEKMSAEKISELLA 737 KL KE + N D N + E M L T++L+++ + K+ + + Sbjct: 733 --FKLAKEISPNAVHSTSFNKMADEFNMMSQTFNETMKLKEAATNQLKRIDS-KVYGITS 789 Query: 738 KINHE---EQSKIQTQFG--IDAKIQERDLYIENIESELSKYKSRICRLEESIAVMED-- 790 + N E + K T+ ++ + Q ++++ ++ I L+ + D Sbjct: 790 RYNIETVDDTVKALTELDNLLNIEKQRTQKNLDDLANKTEDLMDEIDSLQSVNVSLTDQN 849 Query: 791 --------RRYSLERKADQLGSYLQEKQKAYSEYTI--QEDELVNRLAV----LMDHDRV 836 R +ER + L L + ++Y + Q E ++ L D + Sbjct: 850 KKQQIEIIRLQGIERSVEGLNEDLNSAYQLINQYELANQNSEYAQQMKFIKKKLKDKQKQ 909 Query: 837 VEK------QLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAE 890 ++K +LL+++ EN L+K+ L E + + +L + +L + R E Sbjct: 910 IQKYKSSVNELLDVQSENNSLKKQISDLNENIREMNGALKAANKKLQSLDKLHQRKLEME 969 Query: 891 SESTKYQTQLRDLE---SNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVL- 946 + + T R L+ +L++ E + +K +E + N+QI+ + + ++ Sbjct: 970 DQISSLMTACRQLQMDKESLQKKVDELKKSNEEKDDALESYRDKLNSQIDILGQSQSIIE 1029 Query: 947 --NEKYEKNIEYVTQLEAQLQEYKNNIENL--NMN-VEELNKMNLELIDKHVQK--QQTQ 999 N+K K+ + +L+ +L IE + MN E NK N E + K QK + T+ Sbjct: 1030 NANDKSRKDSNAIQELKEKLINSDKEIEKMKKEMNDYENTNKSNKENLLKLQQKIIEVTR 1089 Query: 1000 SPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLEN 1059 + + TE ++ + ++ LL D + A + K + ++ + V D + +F + N Sbjct: 1090 TVNPTENHVRVSDNVSQLLNDLDLIVKAFSDK--DKTINEIKGVIDKNNN--EFISFKSN 1145 Query: 1060 MEEEMQRVSKQLLDSKQHNEELQI---LVREQDDQIKELK-------ETKLTFE--MNIP 1107 + + S++L+ +N+ L + V+ Q DQI E+K + T++ ++ P Sbjct: 1146 LSNIISSFSQKLVSETDNNKLLNLTNDFVKSQVDQINEIKSQIVQIIKNSSTYKPTLSSP 1205 Query: 1108 KTEGM-IISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNT 1166 + E + I+ I N + L + + + Q+ + ++ L Sbjct: 1206 QNELLDILREIISEHEVTENKLGSEVTYLNDILNQLDI-KNSDLAQQIAEHRQGYEILKQ 1264 Query: 1167 ELQECYTKIIQLET--LNTELTGHDVVNQ--EQINQLKSKLEQLNTENDNLLSTVAELRS 1222 +L E I + E+ + ++V++Q +I++L+ KL + N+ N +L S V EL+ Sbjct: 1265 KLDEASHIIEEKESNVFEEKQQTNEVISQAKAKISRLERKLTESNSSNKDLQSKVDELKK 1324 Query: 1223 SISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEE 1282 + Q ++ E ++ ++R+++ ++ EQL + T+ + Sbjct: 1325 KL----------------QESSENEIKIKQNTEQMRIEMEKRITEQEQLKKQL---TELQ 1365 Query: 1283 TNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAF---XXXXX 1339 TN I +Q+ L N L+ E+ LQ K+ + + + + + + + Sbjct: 1366 TNNINNQKQINDLNNTLKISEKQRTELQVKFDEQTKSNKEIVDQKQQQIYSLNNEISKMK 1425 Query: 1340 XXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAE 1399 DL TE S + I N +L + + Sbjct: 1426 ADIEKQNALNNDLNTEKSSLNVKIVKFESEIKSLNEKLTNMKEIIANSQLEKKKLEEEIK 1485 Query: 1400 AKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESEL 1459 ++V EL++ L+ +++++ +HE IT+ + ++FEN Q++ +K IE+ T Sbjct: 1486 SRVKELSN-LQEENAKLLTSSHEKEITM--QKEKFENETQKM---KKEIEEKTANISELE 1539 Query: 1460 AILRLKMHENANHYETMQKE-SEIE-RVKLIEELNVKITESVSLNKQVAELNKALEEEVA 1517 L K + N +QK+ S++E ++++ EE K+ ES +K+V +L + + Sbjct: 1540 KALSDKERNHKNLLSKIQKKYSQLEDKLEIAEE---KLEES---DKKVKDLKNII--TLH 1591 Query: 1518 KTNEMQTALENQEIEIVT-LNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTM 1576 K N++Q +EN+ +++ +N + +N + ++ + K+ + ++ Sbjct: 1592 KQNQVQ--MENEHNQLINDMNKQHDQEKNNLSLQLKSLENQIENLIQEKESYETEISTVY 1649 Query: 1577 NKELLDAVPRAELDLAMYMLHQRDVR 1602 D++ +A L+ A + ++ ++ Sbjct: 1650 GDR--DSMKQA-LEKASAFIQKKSIK 1672 Score = 111 bits (267), Expect = 2e-22 Identities = 184/936 (19%), Positives = 397/936 (42%), Gaps = 76/936 (8%) Query: 660 KSVHLEEQIDALSASKKELALVIENLKLDKE----QLYGTIKDLEN---DKEDIMNKLQN 712 KS+ LEE+ A + L + +E D + QL ++ D E++ N+ Sbjct: 181 KSILLEERRQASERFGRSLFIELEQKNADLQDEISQLQSKLEAASRNAVDSEEMQNQNSQ 240 Query: 713 YIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAK----IQERDLYIENIE 768 QE + L KL++ + E +++ + I +E + + + + Y ++++ Sbjct: 241 VQQEILILKQKLQQQT-ETLNQYVVDITNERNKNNELEQQLQELHFNGVANPQQYAQDLD 299 Query: 769 SELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLA 828 EL KS +L E I+ ++ E K L +QEK + Y + +E N L Sbjct: 300 -ELRNVKSENTKLNERISQLQMINDENESKIQNLVKQIQEKDEKYGDVAQSLEERQNNL- 357 Query: 829 VLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDL 888 + + + +++++ EN L K+ L E Q + + ++Q + + EK+ Sbjct: 358 ------KEMSENIIKLQSENSALTKERNSLSSELQQKTMFIDELQSNLKQVEEKSRTVYR 411 Query: 889 AESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNE 948 + ++ST +++ L+ + E + L K ++ ++ + T + I K N Sbjct: 412 SGNKSTIVDDRVKTLQERFNAVNSEKEEL----KLTLDQVK-QLVTDQQRQILQLKKENS 466 Query: 949 KYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYI 1008 + ++NI T +++ NL+ + ++ K N E IDK + K T+ + QY Sbjct: 467 ELKQNINEKTD--------EDDSFNLSTMINKMQKENSEDIDK-LHKSITELQNQV-QYW 516 Query: 1009 NE--INKLNALLKQKDEEIIALNQKINNAQVSYMSMV-SDYESKLAQFTTKLENMEEEMQ 1065 E +++ N+ + +++ I+L + + N + + +D + ++ + +++ ++++ Sbjct: 517 KEKCLSQENSFKENQEKFRISLMENVTNQTILPLQQSNNDKDQQIKELMNQIKLIKDKQD 576 Query: 1066 RVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTF-EMNIPKTEGMIISSTIEPMSDD 1124 V + +K +++++ L++E + + K+ K+ LT PK + + I+ + + Sbjct: 577 EVESK---NKAKDQQMKKLIKELEKEQKKNKDLTLTIANAEDPKHIQTQMQARIDDLQSE 633 Query: 1125 ANNVDXXXXXXXXXXXXLKVQ------EEEEFIQERSVLQEQSAKL--NTELQECYTKII 1176 +N+ LK + + E S LQE+ K+ NT+L KI Sbjct: 634 ISNLKQEIQQNEQKYQNLKKENKSLKNDNESANHTISALQEEIKKISDNTDLTR---KIE 690 Query: 1177 QLETLNTELTGHDVVNQEQINQLK-SKLEQLNTENDNLLSTVAELRSSIS-SAVDQRGF- 1233 + E +L ++ + I+ K K E L+ +N L + +L IS +AV F Sbjct: 691 EQEKEVDQLRKYNEKLETTISSSKQQKEEMLHNQNKALKQMIFKLAKEISPNAVHSTSFN 750 Query: 1234 EIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVT 1293 ++A+ + ++Q + K + QL +SK + T ++T K +T E Sbjct: 751 KMADEFNM-MSQTFNETMKLKEAATNQLKRIDSKVYGITSRYNIETVDDTVKALT-ELDN 808 Query: 1294 SLQNKLQDKEEHLRNLQEKYADVINQIEILRS---EIEDEKVAFXXXXXXXXXXXXXXXX 1350 L + Q +++L +L K D++++I+ L+S + D+ Sbjct: 809 LLNIEKQRTQKNLDDLANKTEDLMDEIDSLQSVNVSLTDQNKKQQIEIIRLQGIERSVEG 868 Query: 1351 DLRTENQSYKQMQEQSILNINEENAQ----LKKSSXXXXXXXXXXXXRVNDAEAKVLELT 1406 N +Y+ + + + N N E AQ +KK VN+ V Sbjct: 869 LNEDLNSAYQLINQYELANQNSEYAQQMKFIKKKLKDKQKQIQKYKSSVNEL-LDVQSEN 927 Query: 1407 HQLELKDSEIYQKTHEYTITLTQRNDEFEN---VRQQLVEYEKRIEDL---TYEKESELA 1460 + L+ + S++ + E L N + ++ + Q+ +E E +I L + + + Sbjct: 928 NSLKKQISDLNENIREMNGALKAANKKLQSLDKLHQRKLEMEDQISSLMTACRQLQMDKE 987 Query: 1461 ILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTN 1520 L+ K+ E E E R KL ++++ + +S S+ + N ++ Sbjct: 988 SLQKKVDELKKSNEEKDDALESYRDKLNSQIDI-LGQSQSI---IENANDKSRKDSNAIQ 1043 Query: 1521 EMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQK 1556 E++ L N + EI + E+ + +N +++ + K Sbjct: 1044 ELKEKLINSDKEIEKMKKEMNDYENTNKSNKENLLK 1079 Score = 92.7 bits (220), Expect = 8e-17 Identities = 176/923 (19%), Positives = 382/923 (41%), Gaps = 73/923 (7%) Query: 141 LGDVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIE--AKNKATTXXXX 198 L VT L + ++EK+ ++ L K+ E+TI + + + IE K+K+T Sbjct: 1977 LQTVTQLKSLVEEKEKQIASLNKKVADYESTIHESEIYQTKTKLEIEDITKSKSTLQQLL 2036 Query: 199 XXXXXXXXXXXXXE-DTKQQMTKMQENFIAM-EAEWKDEKQRLLKDIESKDVRISSLEEA 256 D K ++ + + E+E K + ++ + + D+ + + E Sbjct: 2037 DTISNDKSNLEKQILDQKSTVSLLTAQISNLQESEQKLKLTQIQNNTQINDLN-NKISEM 2095 Query: 257 NKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSL 316 K + + EI H ELE A + IE + I +K + Sbjct: 2096 TKT-DQTKSEIIQNHQNKIHELELQLLDKNNELNN----ANKEIENIKSQTESIIQKTAF 2150 Query: 317 EIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGR 376 EI N TE+ L + + K+ T+ +K+ SS +K L+ + Sbjct: 2151 EIQNKTEI------LNNYETKFENMKKQNAKAAVTINDMTKS-SSDLRKHVNLLENQLF- 2202 Query: 377 NTASKMKSPWSQLS-SETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXX 435 ++ K+++ +L+ S+ Q K+IN++ A + L+++ KE + +++ Sbjct: 2203 DSKMKIENLTKELNESQNKIQSMTKQINESR-AFSSTLQTKLDRESKQKESL--QRELNF 2259 Query: 436 XXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDE--I 493 + + ++ H ME E + + L++ + D Sbjct: 2260 TQTELTKIQTEASEYKSKILHTSEMESAMQNSYSLIEEKLKSEENKRRNLERLITDMRLT 2319 Query: 494 KDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDS 553 +DVN ++++S + + L +E D + + + L +++ K + + S Sbjct: 2320 RDVNSSPKKQEIESLKINLQNLENENDKLINEIKTLNEKNVLLQQEISKLSSDLQEKEKS 2379 Query: 554 NKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYD-SGRMIESDVYKKMIEMENLAETR 612 K +++ +L ++E+ + K +++ H ++ S ++ D+ K ++E + Sbjct: 2380 EKSLLQKQNDL------ISEISKLKNDIKDHKINLSQSTSSLKKDISTKAKQIEQSKDE- 2432 Query: 613 LKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCS-EIKSVHLEEQIDAL 671 ++ L+++ L +++ L+ + ED LA +Q Q S ++ + EE L Sbjct: 2433 ---LNNLQTENNSLKKKIQNLEAVLQDTEDSLAQSNQSQRQIKASYDLLNNKFEENQVLL 2489 Query: 672 SASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEK 731 ++ +KE+ + + +++L T +L N +E I + Q+ + KLE ++ E Sbjct: 2490 NSKQKEIERLTNEVSDKEKELEKTKSELINIQERIRSDSSKLNQDINEKQTKLESLNIEL 2549 Query: 732 ISELLAKINHEEQSKIQTQFGIDAKIQE-RDLYIENIESELSKYKSRICRLEESIAVMED 790 E + IN E SK+ + + +++Q D ++I + +S+Y EE + Sbjct: 2550 --EKMRNINRELTSKVNS---LTSQLQSIADSNQKDINTYISQYN------EE-----KS 2593 Query: 791 RRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKE 850 R LE+ + L L+EK K +++ L + L ++ L+ +++ + Sbjct: 2594 TRKELEKSNETLKKKLEEKVKENKNLSVKITSLKTNIEELQIEVTRTQRTLVP-KNQLES 2652 Query: 851 LQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTD-----LAESESTKYQTQLRDLES 905 LQK + + + Q +L++ + Y++++EK N L ES + + +S Sbjct: 2653 LQKSVNEMSRKLDDAQQNLAEQKSRYSSIIEKYNEKTSLLSLLTESFISVHSLIANQSKS 2712 Query: 906 NLKRITHEHQTL----IVQKKKEIEDLEIEFN--TQIESAIRDKKVLNEKYEKNIEYVTQ 959 NL + Q L + K + +I F +++ ++ + + K N +T+ Sbjct: 2713 NLSQKQFLMQILEKMSAIFKAMNLSMPQISFAQLNRLDVSVSSVDIFDIKMTHNFRLLTE 2772 Query: 960 LEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLK 1019 + +L I + +N+ +L E + QQ E N ++++ +++ Sbjct: 2773 EDEKL------INAIKLNLSDLAVSTSERLPSFTASQQLSGK--LEYIRNLVSRVKSVID 2824 Query: 1020 QKDEEIIALNQKINNAQVSYMSM 1042 QKD EI LNQ+I + M + Sbjct: 2825 QKDSEIDRLNQQIAKQHETVMKI 2847 >UniRef50_Q22AT3 Cluster: Viral A-type inclusion protein repeat containing protein; n=1; Tetrahymena thermophila SB210|Rep: Viral A-type inclusion protein repeat containing protein - Tetrahymena thermophila SB210 Length = 3812 Score = 186 bits (452), Expect = 6e-45 Identities = 225/1129 (19%), Positives = 510/1129 (45%), Gaps = 104/1129 (9%) Query: 233 KDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXX 292 K+E + + IE V I L+ A+KL + + +I + + ++++ Sbjct: 2699 KEELKLKIISIEEMSVVIDDLK-ASKLQQDNQIQIIQQQLQESEQINSQLHSQVENYQEN 2757 Query: 293 XXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELE---NKL 349 + ++E +EK EI + + TE ++E+ + L QI + N+ + N+L Sbjct: 2758 IKQIQDTLEQLKQEKQEITNQ-----SEQTEKDLQLEIQKLLQ-QIEEQNQNFQVQINEL 2811 Query: 350 ATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAK 409 + +G +K V ++ +K+ ++ ++K+ S + +T+ Q KI Sbjct: 2812 SNLGANNKLVIQEKQE-----LQKNIQDLKDQLKTTQSN-NKQTI-QSLQAKIE------ 2858 Query: 410 LEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVG 469 E+ Q ++ ++ + + ++ K+ + + E + +E L V Sbjct: 2859 -ELTTQICQQNELNNQ--LKSQNQQNIHQIEELNIKNNFLNKTLKEQVEQLE-QELNSVQ 2914 Query: 470 TNTEDVNEIAKVQEQLKQELNDEIKDVN--VKDLIEKLKSAEEQITQLNDEIDAANKNMI 527 E+ N+I+K Q+ + L + +N ++DL ++ E QI QL ++++ K + Sbjct: 2915 EKLEEKNKISKEQQNQFEALQENCVQLNQKIQDLQLNKQNQEHQIQQLQNQLNVFEKENL 2974 Query: 528 KVKSNHKLKLKQMQKTIDNFSKV-SDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLV 586 K K K+ + + S N E +++L Q++ + EK ++ L Sbjct: 2975 LQKEQISAKTKEANGLREELDVINSQKNLEQTESSKQLQEFCQQMETITREKNQIKQELE 3034 Query: 587 DY--DSGRMIESD---VYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVE 641 + DS +S+ + + E+ + + K +LE + E LQQ+ +V Sbjct: 3035 QFQLDSSNQSKSERQQINQLESELAQIKQREQKQKVILEENSKNHKIEKEELQQQIKQVN 3094 Query: 642 DKLADISQ--LQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDL 699 L + +Q ++ +++ H EQI+ LS +K L L L +++ G I + Sbjct: 3095 SVLKAEQENFIQKEKSLNQVIKGH-SEQIEQLSNEQKALQ---NQLNLKNQEIAGLILQM 3150 Query: 700 ENDKEDIMNKLQNYIQENMDLTDKLEK-----MSAEKISELLAKINHEEQSKIQTQFGID 754 +N +E Q +Q N D+++ E+ + EK+ E L ++N+ K+ ++ Sbjct: 3151 KNKEEQQQQLSQKIVQLNQDISNITEQSNIKIQNGEKLIEELQELNNSNHEKLND---LE 3207 Query: 755 AKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYS 814 +K++ + + I+S S+Y+ I +L++++ + LE++ + +++K K Sbjct: 3208 SKLKAQQ---QTIKSSASEYQKNIKQLQDNLQKQTNVNSELEKQNQENLKLIKQKDKQLE 3264 Query: 815 EYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQ 874 E Q++++ ++ + +++ K+ + + E K+L K + ++ Q ++ L ++++ Sbjct: 3265 EINTQKEKMSSQYQEEKEQSQIINKKYQQQDQELKQLLVKLENYEKQEQEIKNKLINVEE 3324 Query: 875 HYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNT 934 + L++ N ++ ++ +LE ++KRI EH + + + +L ++ NT Sbjct: 3325 EKSKLIDSQNILEV----------KVLNLEEHIKRIQEEHSCKTKEFENKQNEL-LQSNT 3373 Query: 935 QIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQ 994 + + + + +++E + L L++ K E+ N+EE+ K +LI ++ Q Sbjct: 3374 LLSKQSANLEDVYKQFELKQNDLLNLIQLLEKEKQEKESAIQNLEEIKK---QLISQNKQ 3430 Query: 995 KQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFT 1054 Q+ ++N+ A LK + + LN++++N+++ M+S+ ++K+ Q T Sbjct: 3431 NQE------------KLNQAEADLKNQ----VQLNKELDNSKIQLEKMLSELQNKIEQNT 3474 Query: 1055 TKLENMEEEMQRV-------SKQLLDSKQHNEELQILVREQDDQIKEL--KETKLTFEMN 1105 +M+++++++ +KQ+ K +EL+ + Q +I EL K +++ E+N Sbjct: 3475 QNANSMKDQLKKLQIQVDDQNKQINSEKAKADELKSTIENQVQKISELQNKNNQISKELN 3534 Query: 1106 IPKTEGMIISSTI--EPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQ-ERSVLQEQSA 1162 K + + + + + ++QE+ + +Q E + L++Q+ Sbjct: 3535 QEKASAQDLKEQFNNQKLVLEQQQKENINTSNNFKETNKQLQEQVKLLQSEINQLKQQND 3594 Query: 1163 KLNTELQ-ECYTKIIQLETLNTEL---TGHDVVNQEQINQLKSKLEQLNTENDNLLSTVA 1218 KLN + Q E T++ LE L +++ T QEQI QL K Q D LL Sbjct: 3595 KLNDKHQKELLTQVSILEELQSKIKSQTEQSSNYQEQIKQLSDKNIQNEQVIDQLLCKSK 3654 Query: 1219 ELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSS 1278 +L + ++ ++ +++ + Q E + + L Q +S + +L + Sbjct: 3655 DLETKFILEQEENQ-KLVNDYEEKMNQLELAKSEEVNSLIEQFKQEKSLWNELKNEENGK 3713 Query: 1279 TQEETNKIVT-----MEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEI 1322 + E N++ T EQV LQ + DKE + +++ + + ++QI++ Sbjct: 3714 IESERNELKTKMFELFEQVKVLQMVVSDKESEINTIKQSHKEELDQIQL 3762 Score = 175 bits (427), Expect = 6e-42 Identities = 300/1500 (20%), Positives = 628/1500 (41%), Gaps = 142/1500 (9%) Query: 150 TIKEKDNALSVLQVKM---KIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXX 206 TIK+K+ + L+V++ ++ I LQ+ + EK QII+ K Sbjct: 2032 TIKQKEQIILNLRVQVDDISNLQEQISQLQDALQEKQQIIDQIEKENIQQIYEETLIQKN 2091 Query: 207 XXXXXEDT----KQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEA 262 + KQ++ K EN I E + K + L+ + + +++ + LE+ N +++ Sbjct: 2092 ELLSINNKLNQEKQELQKAIEN-INQEIQQKSNQIDHLQTLNN-EIK-TELEQKNGKIKS 2148 Query: 263 ARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMT 322 +I+ E+ + Q L K + T + E ++ N Sbjct: 2149 QEDQIA-ENIQNIQVLNTENNQLKEEFSLKLNAYKSENIEQINQLTAVFENEKTQLENAI 2207 Query: 323 ELTKKIELLEHLNCQIRQTNKEL-ENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASK 381 + K+I ++L Q+ N+ + + + +S+++ ++ + L+ ++ + + Sbjct: 2208 KQQKEIN--QNLENQVVNQNQNIIKMQQENQLIQSESIEKQKREFTELLKQQDEKLLNLR 2265 Query: 382 MKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXX 441 + S+ ++ L + ++K N+N I +L+ IQSL + L + +I+E Sbjct: 2266 NQFEDSKEENQLLREQNEQK-NQN-IQQLQQEIQSLQQQL---DNLINETSILRTENSEQ 2320 Query: 442 XXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVK-D 500 + L+ +Q +E + + T+ D + K QE+L+ +L + + + Sbjct: 2321 IQNLKKEREEFLLKMEQLVEAINKLKK-TSANDKQIMQKEQEELQSKLALVVSQAQINVN 2379 Query: 501 LIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRL 560 I++L+ ++Q L D++ K + K+ Q + + + + K + Sbjct: 2380 TIDELRQTKQQ---LEDQVLLLTKQADSLTLQSKMSESQFTEEMKKQILIFEQEK--INF 2434 Query: 561 TEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIES-DVYKKMIEMENL-----AETRLK 614 + + L QK+AE E + N Q+ L+ + +++ YK M + E ++ + Sbjct: 2435 EKTISQLEQKLAENELDSSN-QIQLLQEEQQKIVNQLQEYKNMYQTERQQNELNTQSLQQ 2493 Query: 615 AISLLESQKF----------DLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIK---- 660 + E QK D+V++ + +Y+E+ + + QL +Q IK Sbjct: 2494 QFEICERQKLQIEEIQQRLEDIVEQNKETKNEYNELSVQKMSLEQLFEEQRGEFIKESDR 2553 Query: 661 SVHLEEQIDALSASKKELALVIENLKLDKEQLYGT-IKDLENDKEDIMNKLQNYIQENMD 719 + LE I L + K L ++NL +Q Y I ++EN++ NK Y EN Sbjct: 2554 NQKLENAIKNLESENKSLKDKLDNL----DQNYSNQILEIENER----NKCLQYEHENQS 2605 Query: 720 LTDKLEKMSAEKISEL----LAKINHEEQSKIQTQFGIDAKIQERDLYIENI---ESELS 772 L +K KI+EL + I E+ KIQ + + +Q L I+ + +L Sbjct: 2606 LQEKCFSYQ-NKITELDETKKSLIRQLEEFKIQIK-DEQSTVQTLKLEIQKLIKQNEDLQ 2663 Query: 773 KYKSRIC--RLEESIAVMEDRRYSLERKA---DQLGSYLQEKQKAYSEYTIQEDELVNRL 827 K I ++ + ++E + + L++ A +Q+ L+ K + E ++ D+L Sbjct: 2664 KENQDIIENQVNAQLDILEKQNFDLQQLAQFNNQIKEELKLKIISIEEMSVVIDDLKASK 2723 Query: 828 AVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTD 887 + +++++QL E E N +L + + E + +Q +L ++Q + ++ +T+ Sbjct: 2724 LQQDNQIQIIQQQLQESEQINSQLHSQVENYQENIKQIQDTLEQLKQEKQEITNQSEQTE 2783 Query: 888 L-AESESTKYQTQLRDLESNLKRITHE------HQTLIVQKKKEIEDLEIEFNTQIESAI 940 + E K Q+ + N + +E + L++Q+K+E++ + Q+++ Sbjct: 2784 KDLQLEIQKLLQQIEEQNQNFQVQINELSNLGANNKLVIQEKQELQKNIQDLKDQLKTTQ 2843 Query: 941 RDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNM-NVEELNKMNLE--LIDKHVQKQQ 997 + K + + IE +T Q E N +++ N N+ ++ ++N++ ++K +++Q Sbjct: 2844 SNNKQTIQSLQAKIEELTTQICQQNELNNQLKSQNQQNIHQIEELNIKNNFLNKTLKEQV 2903 Query: 998 TQSPDYTEQYINEINKLNALLKQKD-------EEIIALNQKINNAQVSYMSMVSDYESKL 1050 Q ++ + N + K++ E + LNQKI + Q++ + E ++ Sbjct: 2904 EQLEQELNSVQEKLEEKNKISKEQQNQFEALQENCVQLNQKIQDLQLNKQNQ----EHQI 2959 Query: 1051 AQFTTKLENMEEE----MQRVSKQLLDSKQHNEELQILVR----EQDDQIKELKE----- 1097 Q +L E+E +++S + ++ EEL ++ EQ + K+L+E Sbjct: 2960 QQLQNQLNVFEKENLLQKEQISAKTKEANGLREELDVINSQKNLEQTESSKQLQEFCQQM 3019 Query: 1098 TKLTFEMNIPKTE--GMIISSTIEPMSD--DANNVDXXXXXXXXXXXXLKVQEEEEFIQ- 1152 +T E N K E + S+ + S+ N ++ KV EE Sbjct: 3020 ETITREKNQIKQELEQFQLDSSNQSKSERQQINQLESELAQIKQREQKQKVILEENSKNH 3079 Query: 1153 --ERSVLQEQSAKLNTELQECYTKIIQLE-TLNTELTGHDVVNQEQINQLKSKLEQLNTE 1209 E+ LQ+Q ++N+ L+ IQ E +LN + GH ++ N+ K+ QLN + Sbjct: 3080 KIEKEELQQQIKQVNSVLKAEQENFIQKEKSLNQVIKGHSEQIEQLSNEQKALQNQLNLK 3139 Query: 1210 NDNLLSTVAELRSS------ISSAVDQRGFEIAELWKQHLAQRE------ADFQKTEHEL 1257 N + + ++++ +S + Q +I+ + +Q + + + Q+ + Sbjct: 3140 NQEIAGLILQMKNKEEQQQQLSQKIVQLNQDISNITEQSNIKIQNGEKLIEELQELNNSN 3199 Query: 1258 RVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVI 1317 +L+ ESK + +++SS E I ++ +LQ + E + QE +I Sbjct: 3200 HEKLNDLESKLKAQQQTIKSSASEYQKNIKQLQD--NLQKQTNVNSELEKQNQENLK-LI 3256 Query: 1318 NQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQL 1377 Q + EI +K + ++Q KQ+ + + N ++ ++ Sbjct: 3257 KQKDKQLEEINTQKEKMSSQYQEEKEQSQIINKKYQQQDQELKQLLVK-LENYEKQEQEI 3315 Query: 1378 KKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENV 1437 K N E KVL L ++ E KT E FEN Sbjct: 3316 KNKLINVEEEKSKLIDSQNILEVKVLNLEEHIKRIQEEHSCKTKE-----------FENK 3364 Query: 1438 RQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITE 1497 + +L++ + + E LK ++ N + ++KE + E+ I+ L + Sbjct: 3365 QNELLQSNTLLSKQSANLEDVYKQFELKQNDLLNLIQLLEKEKQ-EKESAIQNLEEIKKQ 3423 Query: 1498 SVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNL--QNMVRASSSKIQ 1555 +S NKQ E E ++ ++ L+N +I++ + E+ N QN A+S K Q Sbjct: 3424 LISQNKQNQEKLNQAEADLKNQVQLNKELDNSKIQLEKMLSELQNKIEQNTQNANSMKDQ 3483 Score = 166 bits (403), Expect = 5e-39 Identities = 305/1536 (19%), Positives = 659/1536 (42%), Gaps = 150/1536 (9%) Query: 145 THLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINE--KDQIIEAKNKATTXXXXXXXX 202 T L N IK++ L+ ++ I+ +Q++ N+ + + IE + + T Sbjct: 2201 TQLENAIKQQKEINQNLENQVVNQNQNIIKMQQE-NQLIQSESIEKQKREFTELLKQQDE 2259 Query: 203 XXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEK-QRLLKDIESKDVRISSLEEANKLLE 261 ED+K++ ++E + E K++ Q+L ++I+S ++ +L +L Sbjct: 2260 KLLNLRNQFEDSKEENQLLRE-----QNEQKNQNIQQLQQEIQSLQQQLDNLINETSIL- 2313 Query: 262 AARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANM 321 R E S + L +E E+ L K S + E EE S + Sbjct: 2314 --RTENSEQIQNLKKEREEFLLKMEQLVEAINKLKKTSANDKQIMQKEQEELQSKLALVV 2371 Query: 322 TELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASK 381 ++ + ++ L RQT ++LE+++ + ++ +++ SK + + + Sbjct: 2372 SQAQINVNTIDEL----RQTKQQLEDQVLLLTKQADSLTLQSKMSESQFTEEMKKQI--- 2424 Query: 382 MKSPWSQLSSETLNQDTDKKINKNEIAKLEMV--IQSLNKDLVDKEYVISEKDTXXXXXX 439 + +++ E ++K+ +NE+ + +Q + +V++ + K+ Sbjct: 2425 LIFEQEKINFEKTISQLEQKLAENELDSSNQIQLLQEEQQKIVNQ--LQEYKNMYQTERQ 2482 Query: 440 XXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELND-EIKDVNV 498 +L Q ++ +Q ++ + + ED+ E K + K E N+ ++ +++ Sbjct: 2483 QNELNTQSLQQQFEICERQKLQ---IEEIQQRLEDIVEQNK---ETKNEYNELSVQKMSL 2536 Query: 499 KDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDN--FSKVSDSNK- 555 + L E+ + + + N +++ A KN+ + K KL + + N ++ NK Sbjct: 2537 EQLFEEQRGEFIKESDRNQKLENAIKNLESENKSLKDKLDNLDQNYSNQILEIENERNKC 2596 Query: 556 -----EIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIE-SDVYKKMIEMENLA 609 E L E+ K+ EL+E K +L L ++ E S V +E++ L Sbjct: 2597 LQYEHENQSLQEKCFSYQNKITELDETKKSLIRQLEEFKIQIKDEQSTVQTLKLEIQKL- 2655 Query: 610 ETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQID 669 +K L+ + D+++ + + D +E + D+ QL Q ++IK E++ Sbjct: 2656 ---IKQNEDLQKENQDIIENQ--VNAQLDILEKQNFDLQQLA--QFNNQIK-----EELK 2703 Query: 670 ALSASKKELALVIENLKLDKEQLYGTIKDLEN---DKEDIMNKLQNYI---QENM-DLTD 722 S +E+++VI++LK K Q I+ ++ + E I ++L + + QEN+ + D Sbjct: 2704 LKIISIEEMSVVIDDLKASKLQQDNQIQIIQQQLQESEQINSQLHSQVENYQENIKQIQD 2763 Query: 723 KLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLE 782 LE++ EK E+ N EQ++ Q I +Q+ + +N + ++++ + + Sbjct: 2764 TLEQLKQEK-QEIT---NQSEQTEKDLQLEIQKLLQQIEEQNQNFQVQINELSNLGANNK 2819 Query: 783 ESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLL 842 I ++ + +++ DQL + ++ + +EL ++ + + ++ Q Sbjct: 2820 LVIQEKQELQKNIQDLKDQLKTTQSNNKQTIQSLQAKIEELTTQICQQNELNNQLKSQNQ 2879 Query: 843 EIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKA-----------NRTDLAES 891 + H+ +EL KN L N+ L+ + ++Q N++ EK N+ + + Sbjct: 2880 QNIHQIEELNIKNNFL---NKTLKEQVEQLEQELNSVQEKLEEKNKISKEQQNQFEALQE 2936 Query: 892 ESTKYQTQLRDLESNLKRITHEHQTL-----IVQKKKEIEDLEIEFNTQIESAIRDK-KV 945 + +++DL+ N + H+ Q L + +K+ ++ +I T+ + +R++ V Sbjct: 2937 NCVQLNQKIQDLQLNKQNQEHQIQQLQNQLNVFEKENLLQKEQISAKTKEANGLREELDV 2996 Query: 946 LNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTE 1005 +N +KN+E T+ QLQE+ +E + E N++ EL + Q + Sbjct: 2997 INS--QKNLEQ-TESSKQLQEFCQQMETIT---REKNQIKQEL--EQFQLDSSNQSKSER 3048 Query: 1006 QYINEINKLNALLKQKDE-EIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEM 1064 Q IN++ A +KQ+++ + + L + N ++ + + ++ Q + L+ +E Sbjct: 3049 QQINQLESELAQIKQREQKQKVILEENSKNHKIEK----EELQQQIKQVNSVLKAEQENF 3104 Query: 1065 QRVSKQLLDS-KQHNEELQILVREQDD-----QIKELKETKLTFEMNIPKTEGMIISSTI 1118 + K L K H+E+++ L EQ +K + L +M + + +S I Sbjct: 3105 IQKEKSLNQVIKGHSEQIEQLSNEQKALQNQLNLKNQEIAGLILQMKNKEEQQQQLSQKI 3164 Query: 1119 EPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKI-IQ 1177 ++ D +N+ +K+Q E+ I+E LQE + + +L + +K+ Q Sbjct: 3165 VQLNQDISNI--------TEQSNIKIQNGEKLIEE---LQELNNSNHEKLNDLESKLKAQ 3213 Query: 1178 LETLNTELTGHDV-VNQEQINQLK-----SKLEQLNTENDNLLSTVAELRSSISSAVDQR 1231 +T+ + + + + Q Q N K S+LE+ N EN L+ + I++ ++ Sbjct: 3214 QQTIKSSASEYQKNIKQLQDNLQKQTNVNSELEKQNQENLKLIKQKDKQLEEINTQKEKM 3273 Query: 1232 GFEIAELWKQHLAQREADFQKTEHELRVQLSAFES--KYEQLLDSVQSSTQEETNKIVTM 1289 + E +Q + +Q+ + EL+ L E+ K EQ + + + +EE +K++ Sbjct: 3274 SSQYQEEKEQSQIINKK-YQQQDQELKQLLVKLENYEKQEQEIKNKLINVEEEKSKLIDS 3332 Query: 1290 EQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXX 1349 + + L+ K+ + EEH++ +QE+++ + E ++E+ Sbjct: 3333 QNI--LEVKVLNLEEHIKRIQEEHSCKTKEFENKQNELLQSNTLLSKQSANLEDVYKQFE 3390 Query: 1350 X---DLRTENQ---SYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVL 1403 DL Q KQ +E +I N+ E QL + + + Sbjct: 3391 LKQNDLLNLIQLLEKEKQEKESAIQNLEEIKKQLISQNKQNQEKLNQAEADLKNQVQLNK 3450 Query: 1404 ELTH---QLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIED---LTYEKES 1457 EL + QLE SE+ K + T D+ + ++ Q+ + K+I E +S Sbjct: 3451 ELDNSKIQLEKMLSELQNKIEQNTQNANSMKDQLKKLQIQVDDQNKQINSEKAKADELKS 3510 Query: 1458 ELAILRLKMHENANHYETMQKESEIERVK---LIEEL-NVKIT------ESVSLNKQVAE 1507 + K+ E N + KE E+ L E+ N K+ E+++ + E Sbjct: 3511 TIENQVQKISELQNKNNQISKELNQEKASAQDLKEQFNNQKLVLEQQQKENINTSNNFKE 3570 Query: 1508 LNKALEEEVAKTNEMQTALENQEIEIVTLND-EITNLQNMVRASSSKIQKHVSFASDTKQ 1566 NK L+E+V L+ Q ++ + E+ +++ SKI+ +S+ ++ Sbjct: 3571 TNKQLQEQVKLLQSEINQLKQQNDKLNDKHQKELLTQVSILEELQSKIKSQTEQSSNYQE 3630 Query: 1567 GRDEQLD-NTMNKELLDAVPRAELDL-AMYMLHQRD 1600 + D N N++++D + DL ++L Q + Sbjct: 3631 QIKQLSDKNIQNEQVIDQLLCKSKDLETKFILEQEE 3666 Score = 159 bits (386), Expect = 6e-37 Identities = 290/1527 (18%), Positives = 649/1527 (42%), Gaps = 148/1527 (9%) Query: 156 NALSVLQVKMKIMETTILDLQEKINEK-----DQIIEAKNKATTXXXXXXXXXXXXXXXX 210 N L L++ + + TTI D Q + N+K + I K Sbjct: 1709 NQLESLKIDNEKLNTTI-DQQNQDNQKINASMQETINKLQKENEQLQKELMDKISKFQTQ 1767 Query: 211 XEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLE 270 +Q++T+ E+++ ++ E +++ L++D+++ +++I +E N+ L E E Sbjct: 1768 IMSQEQKITQSDEDYLLLQEEL-NQQNILIQDLQN-ELKIQ--QEKNQELILKLNEQQSE 1823 Query: 271 HSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIEL 330 ++KL + + L E E+ +++ L + L K E+ Sbjct: 1824 YAKLIEVSGESEEKVKKSRKEQSNLQVSYNEVLNEKNILLQKLEELHQQSNINL-KNYEV 1882 Query: 331 LEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLS 390 + Q+ Q ++LEN TM + K + + L K+ + + K+ SQL Sbjct: 1883 TKQSLDQVIQERQQLENANQTMQNQIKKLEE-----NHLAQSKNYEDQSQNFKNQVSQLE 1937 Query: 391 SETLNQ--DTDKKINK------NEIAKLEMVIQSLNKDLVDKEYVISE--KDTXXXXXXX 440 E N+ KK+ + N+I KLE I+SL + +KE +I + K Sbjct: 1938 LELENERESNKKKVEQIQLGYENQIVKLEKQIESL---IGEKEILIEQVNKVQEERDIEK 1994 Query: 441 XXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDV-NVK 499 K + Q+ +E +Q + N E + K +EQ+ L ++ D+ N++ Sbjct: 1995 NENLKKIELNQINIEEKQQKINNLQEEIQQNQEQFMQTIKQKEQIILNLRVQVDDISNLQ 2054 Query: 500 DLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVR 559 + I +L+ A ++ Q+ D+I+ N I ++ L Q + + +K++ +E+ + Sbjct: 2055 EQISQLQDALQEKQQIIDQIEKENIQQI-----YEETLIQKNELLSINNKLNQEKQELQK 2109 Query: 560 LTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLL 619 E +++Q++ + + +LQ ++ + +E K + + +AE ++ I +L Sbjct: 2110 AIE---NINQEIQQKSNQIDHLQT--LNNEIKTELEQKNGKIKSQEDQIAEN-IQNIQVL 2163 Query: 620 ESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELA 679 ++ L +E + Y K +I Q+ E + LE I + L Sbjct: 2164 NTENNQLKEEFSLKLNAY-----KSENIEQINQLTAVFENEKTQLENAIKQQKEINQNLE 2218 Query: 680 LVIEN-----LKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISE 734 + N +K+ +E + +E K + L+ ++ ++L ++ E E ++ Sbjct: 2219 NQVVNQNQNIIKMQQENQLIQSESIEKQKREFTELLKQQDEKLLNLRNQFEDSKEE--NQ 2276 Query: 735 LLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYS 794 LL + N ++ IQ + +IQ ++N+ +E S ++ E I ++ R Sbjct: 2277 LLREQNEQKNQNIQQ---LQQEIQSLQQQLDNLINETSILRTEN---SEQIQNLKKEREE 2330 Query: 795 LERKADQLGSYLQEKQK--AYSEYTIQ--EDELVNRLAVLMDHDRVVEKQLLEIEHENKE 850 K +QL + + +K A + +Q ++EL ++LA+++ ++ + E+ ++ Sbjct: 2331 FLLKMEQLVEAINKLKKTSANDKQIMQKEQEELQSKLALVVSQAQINVNTIDELRQTKQQ 2390 Query: 851 LQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKR- 909 L+ +Q+LL Q ++L E + + E E ++ + LE L Sbjct: 2391 LE--DQVLLLTKQADSLTLQSKMSESQFTEEMKKQILIFEQEKINFEKTISQLEQKLAEN 2448 Query: 910 ---ITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQE 966 +++ Q L +++K + L+ E+ ++ + ++ + ++ E + + Q++E Sbjct: 2449 ELDSSNQIQLLQEEQQKIVNQLQ-EYKNMYQTERQQNELNTQSLQQQFEICERQKLQIEE 2507 Query: 967 YKNNIENL-NMNVEELNKMNLELIDKHVQKQ--QTQSPDYTEQYINEINKLNALLKQKDE 1023 + +E++ N E N+ N + K +Q + Q ++ ++ + KL +K + Sbjct: 2508 IQQRLEDIVEQNKETKNEYNELSVQKMSLEQLFEEQRGEFIKES-DRNQKLENAIKNLES 2566 Query: 1024 EIIALNQKINNAQVSYMSMVSDYES---KLAQFTTKLENMEEEMQRVSKQL--LDSKQHN 1078 E +L K++N +Y + + + E+ K Q+ + ++++E+ ++ LD + + Sbjct: 2567 ENKSLKDKLDNLDQNYSNQILEIENERNKCLQYEHENQSLQEKCFSYQNKITELDETKKS 2626 Query: 1079 -----EELQILVREQDDQIKELK-ETKLTFEMN--IPKTEGMIISSTIEPMSD--DANNV 1128 EE +I ++++ ++ LK E + + N + K II + + D + N Sbjct: 2627 LIRQLEEFKIQIKDEQSTVQTLKLEIQKLIKQNEDLQKENQDIIENQVNAQLDILEKQNF 2686 Query: 1129 DXXXXXXXXXXXXLKVQEEEEFIQERSVLQE--QSAKL--NTELQECYTKIIQLETLNTE 1184 D +++ + I+E SV+ + +++KL + ++Q ++ + E +N++ Sbjct: 2687 DLQQLAQFNNQIKEELKLKIISIEEMSVVIDDLKASKLQQDNQIQIIQQQLQESEQINSQ 2746 Query: 1185 LTGHDVVNQEQINQLKSKLEQLNTENDNLLS----TVAELRSSISSAVDQ-----RGF-- 1233 L QE I Q++ LEQL E + + T +L+ I + Q + F Sbjct: 2747 LHSQVENYQENIKQIQDTLEQLKQEKQEITNQSEQTEKDLQLEIQKLLQQIEEQNQNFQV 2806 Query: 1234 ---EIAELWKQH--LAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVT 1288 E++ L + + Q + + QK +L+ QL +S +Q + S+Q+ +E T +I Sbjct: 2807 QINELSNLGANNKLVIQEKQELQKNIQDLKDQLKTTQSNNKQTIQSLQAKIEELTTQICQ 2866 Query: 1289 MEQVTSL------QNKLQDKEEHLRN------LQEKYADVINQIEILRSEIEDE-KVAFX 1335 ++ + QN Q +E +++N L+E+ + ++ ++ ++E++ K++ Sbjct: 2867 QNELNNQLKSQNQQNIHQIEELNIKNNFLNKTLKEQVEQLEQELNSVQEKLEEKNKISKE 2926 Query: 1336 XXXXXXXXXXXXXXXDLRTEN-QSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXR 1394 + + ++ Q KQ QE I + + +K + Sbjct: 2927 QQNQFEALQENCVQLNQKIQDLQLNKQNQEHQIQQLQNQLNVFEKENLLQKEQISAKTKE 2986 Query: 1395 VNDAEAKVLELTHQLELKDSEIYQKTHEY-----TIT-----LTQRNDEFE--------N 1436 N ++ + Q L+ +E ++ E+ TIT + Q ++F+ + Sbjct: 2987 ANGLREELDVINSQKNLEQTESSKQLQEFCQQMETITREKNQIKQELEQFQLDSSNQSKS 3046 Query: 1437 VRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEE-LNVKI 1495 RQQ+ + E + + ++ + IL EN+ +++ ++KE +++K + L + Sbjct: 3047 ERQQINQLESELAQIKQREQKQKVIL----EENSKNHK-IEKEELQQQIKQVNSVLKAEQ 3101 Query: 1496 TESVSLNKQVAELNKALEEEVAKTNEMQTALENQ-EIEIVTLNDEITNLQNMVRASSSKI 1554 + K + ++ K E++ + + Q AL+NQ ++ + I ++N Sbjct: 3102 ENFIQKEKSLNQVIKGHSEQIEQLSNEQKALQNQLNLKNQEIAGLILQMKNKEEQQQQLS 3161 Query: 1555 QKHVSFASDTKQGRDEQLDNTMNKELL 1581 QK V D ++ N E L Sbjct: 3162 QKIVQLNQDISNITEQSNIKIQNGEKL 3188 Score = 158 bits (384), Expect = 1e-36 Identities = 269/1347 (19%), Positives = 582/1347 (43%), Gaps = 112/1347 (8%) Query: 297 KQSIEPSCEEKTEIEEKGSLEIANMTELTKKI-ELLEHLNCQIRQTNKELENKLATMGTE 355 K+++E +E +E E+ EI +L + + E ++ I Q ++ T+ Sbjct: 1560 KENLERQLKEMSEQIEQQEQEIQQQQQLIELLHEQIQEKENIISQDQQKFNEATQTIKQN 1619 Query: 356 SKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKN------EIAK 409 + + K+ ++S+ + T KS Q+ NQ+ + + KN +I Sbjct: 1620 EQEYLNLKKQLDDVVSKNNKLETELYEKSQQIQIRGNE-NQELIQNLQKNNQQLEQDILD 1678 Query: 410 LEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVG 469 + LN + D + SEK+T +L Q + I+ Sbjct: 1679 YKKKEDELNLLIKDLQQKSSEKETQLQINFNQLESLKIDNEKLNTTIDQQNQDNQKINAS 1738 Query: 470 TNTEDVNEIAKVQEQLKQELNDEIK--DVNVKDLIEKLKSAEEQITQLNDEIDAANKNMI 527 E +N++ K EQL++EL D+I + +K+ ++E L +E++ +N++ Sbjct: 1739 MQ-ETINKLQKENEQLQKELMDKISKFQTQIMSQEQKITQSDEDYLLLQEELN--QQNIL 1795 Query: 528 KVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVD 587 ++LK++Q +K + K+++ E +L E +KV + +E+ NLQ V Sbjct: 1796 IQDLQNELKIQQ-EKNQELILKLNEQQSEYAKLIEVSGESEEKVKKSRKEQSNLQ---VS 1851 Query: 588 YDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADI 647 Y+ ++ + +K+ E+ + LK + + ++QE L+ ++++ I Sbjct: 1852 YNEVLNEKNILLQKLEELHQQSNINLKNYEVTKQSLDQVIQERQQLENANQTMQNQ---I 1908 Query: 648 SQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIK-DLENDKEDI 706 +L+ + + +S + E+Q +L L +EN + ++ I+ EN + Sbjct: 1909 KKLEENHLA---QSKNYEDQSQNFKNQVSQLELELENERESNKKKVEQIQLGYENQIVKL 1965 Query: 707 MNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQ-TQFGIDAKIQERDLYIE 765 ++++ I E L +++ K+ E+ E +E KI+ Q I+ K Q+ + E Sbjct: 1966 EKQIESLIGEKEILIEQVNKVQEERDIE-----KNENLKKIELNQINIEEKQQKINNLQE 2020 Query: 766 NIESELSKYKSRICRLEE---SIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDE 822 I+ ++ I + E+ ++ V D +L+ + QL LQEKQ+ + E E Sbjct: 2021 EIQQNQEQFMQTIKQKEQIILNLRVQVDDISNLQEQISQLQDALQEKQQIIDQI---EKE 2077 Query: 823 LVNRLAVLMDHDRVVEKQLLEIEHE-NKELQKKNQILLEENQNLQISLSDMQQHYNALVE 881 + ++ + + + +LL I ++ N+E Q+ + + NQ +Q S+ H L Sbjct: 2078 NIQQI---YEETLIQKNELLSINNKLNQEKQELQKAIENINQEIQ-QKSNQIDHLQTLNN 2133 Query: 882 KANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIR 941 + +T+L E ++ K ++Q + N++ I Q L + + E+ ++ N I Sbjct: 2134 EI-KTEL-EQKNGKIKSQEDQIAENIQNI----QVLNTENNQLKEEFSLKLNAYKSENIE 2187 Query: 942 DKKVLNEKYEKNIEYVTQLEAQLQEYKNNIEN----LNMNVEELNKMNLELIDKHVQKQQ 997 L +E + Q +E N+EN N N+ ++ + N + + ++KQ+ Sbjct: 2188 QINQLTAVFENEKTQLENAIKQQKEINQNLENQVVNQNQNIIKMQQENQLIQSESIEKQK 2247 Query: 998 TQSPDYTEQYINEINKL----------NALLK----QKDEEIIALNQKINNAQVSYMSMV 1043 + + +Q ++ L N LL+ QK++ I L Q+I + Q +++ Sbjct: 2248 REFTELLKQQDEKLLNLRNQFEDSKEENQLLREQNEQKNQNIQQLQQEIQSLQQQLDNLI 2307 Query: 1044 SDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVR--EQDDQIKELKETKLT 1101 ++ + + +++N+++E + LL +Q E + L + D QI + ++ +L Sbjct: 2308 NETSILRTENSEQIQNLKKEREEF---LLKMEQLVEAINKLKKTSANDKQIMQKEQEELQ 2364 Query: 1102 FEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQ---EEEEFIQE--RSV 1156 ++ + ++ I +TI+ + ++ L +Q E +F +E + + Sbjct: 2365 SKLALVVSQAQINVNTIDELRQTKQQLEDQVLLLTKQADSLTLQSKMSESQFTEEMKKQI 2424 Query: 1157 LQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQ-INQLKSKLEQLNTENDNLLS 1215 L + K+N E I QLE E D NQ Q + + + K+ E N+ Sbjct: 2425 LIFEQEKINFE-----KTISQLEQKLAE-NELDSSNQIQLLQEEQQKIVNQLQEYKNMYQ 2478 Query: 1216 TVAELRSSISSAVDQRGFEIAELWK---QHLAQREADFQKTEHELR---VQLSAFESKYE 1269 T + ++ +++ Q+ FEI E K + + QR D + E + +LS + E Sbjct: 2479 TERQ-QNELNTQSLQQQFEICERQKLQIEEIQQRLEDIVEQNKETKNEYNELSVQKMSLE 2537 Query: 1270 QLLDSVQSSTQEETNKIVTMEQ-VTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSE-I 1327 QL + + +E+++ +E + +L+++ + ++ L NL + Y++ I +IE R++ + Sbjct: 2538 QLFEEQRGEFIKESDRNQKLENAIKNLESENKSLKDKLDNLDQNYSNQILEIENERNKCL 2597 Query: 1328 EDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXX 1387 + E D T+ +Q++E I I +E + ++ Sbjct: 2598 QYEHENQSLQEKCFSYQNKITELD-ETKKSLIRQLEEFKI-QIKDEQSTVQ----TLKLE 2651 Query: 1388 XXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEF-ENVRQQLVEYEK 1446 + D + + ++ +I +K + L Q N++ E ++ +++ E+ Sbjct: 2652 IQKLIKQNEDLQKENQDIIENQVNAQLDILEKQNFDLQQLAQFNNQIKEELKLKIISIEE 2711 Query: 1447 R---IEDLTYEK---ESELAIL--RLKMHENANHYETMQKESEIERVKLIEE-LNVKITE 1497 I+DL K ++++ I+ +L+ E N Q E+ E +K I++ L E Sbjct: 2712 MSVVIDDLKASKLQQDNQIQIIQQQLQESEQINSQLHSQVENYQENIKQIQDTLEQLKQE 2771 Query: 1498 SVSLNKQVAELNKALEEEVAK-TNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQK 1556 + Q + K L+ E+ K +++ +N +++I L++ N +V ++QK Sbjct: 2772 KQEITNQSEQTEKDLQLEIQKLLQQIEEQNQNFQVQINELSNLGAN-NKLVIQEKQELQK 2830 Query: 1557 HVSFASD---TKQGRDEQLDNTMNKEL 1580 ++ D T Q ++Q ++ ++ Sbjct: 2831 NIQDLKDQLKTTQSNNKQTIQSLQAKI 2857 Score = 156 bits (378), Expect = 5e-36 Identities = 257/1410 (18%), Positives = 599/1410 (42%), Gaps = 115/1410 (8%) Query: 216 QQMTKMQENFIAM-EAEWKDEKQRLLKDIE-----SKDVRISSLEEANKLLEAARFEISL 269 +QM ++EN+ + E D +L I SK ++ ++ E NK L +S Sbjct: 987 EQMKNLKENYEKLIEQHQNDSMSNILHQINGGSSPSKSDQLVTVMETNKKLIEEMASLSD 1046 Query: 270 EHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIE 329 + KL E+E + K+++E++ L A M ++ + + Sbjct: 1047 MNKKLMDEIEMLRNMSHSRLDISSTFERNGDNEVL--KSKLEKQTELNEALMQQMKEMKQ 1104 Query: 330 LLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGR-NTASKMKSPWSQ 388 E Q Q N+ + + S KK L+ ++ R K ++ Sbjct: 1105 HYESTLSQQSQQNQVTLQNQQQFTKQKQLFSEQVKKLEELLKKQQDRIEELEKEQADLQL 1164 Query: 389 LSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTL 448 L ++ +N ++ +K+ + + ++ S N+ L ++ + +++ + Sbjct: 1165 LQAQRMNMESKEKLMNQNKQQFDQLL-STNQRLSEQVLNLQQQNQQLQQEVDELRNRSM- 1222 Query: 449 IAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELN--DEIKDVNVKDLIEKLK 506 +Q M S I + N + + ++ + L +++ +++ ++ + Sbjct: 1223 -------YQSIMTDRSSIQIAHN-DRIEQLQEENRILSEQIVALSKVQRNSLPPIEGNST 1274 Query: 507 SAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHH 566 ++ + +L+D + N+ +++V N KL + +QK K +E+ L Sbjct: 1275 VSKNEAIKLHD-LQEQNERILRV--NQKLLTENLQKG----EKEVHMKRELEDLKSR-SQ 1326 Query: 567 LSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDL 626 LS ++ + +E+ +L + + E ++ + E++ + L + L Sbjct: 1327 LSMSMSYIHDEEEQSKLRKILQEQVLSYEIEIKQVQNELQESKKQFSHEKESLNKEIQQL 1386 Query: 627 VQELHILQQKYDEVEDKLADISQL--QSDQVCSEIKSVHLEEQIDALSASKKELALVIEN 684 H+L Q+ E E ++ I L Q+ Q + ++ L+ QI L+ + L EN Sbjct: 1387 KNNAHLLNQQVQEKEIQIKQIENLTTQNIQKQYQYENAILKAQIIQLNEEISQQKLKCEN 1446 Query: 685 LKLDKEQLYGTIKDLENDKEDIMN--KLQNYIQEN----MDLTDKLEKMSAEKISELLAK 738 + K EN +E +N +LQ+ ++E ++L D+++++ EK ++L Sbjct: 1447 IS----------KQNENSQEINLNLIQLQDSLKEKEILIINLEDQVKQLQLEK-NKLFQ- 1494 Query: 739 INHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERK 798 + EE I +Q K+ + E +++EL+ ++I L+ + + + ER Sbjct: 1495 -SSEELKVIHSQQVNQLKLSSQQ-QCEQLKNELN---TQILDLQNQVNQLLQKN---ERL 1546 Query: 799 ADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQIL 858 A+Q Y+Q++Q+ Q E+ ++ + + ++QL+E+ HE ++Q+K I+ Sbjct: 1547 ANQNSEYIQDQQEK-ENLERQLKEMSEQIEQ-QEQEIQQQQQLIELLHE--QIQEKENII 1602 Query: 859 LEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLI 918 ++ Q + ++Q+ + + D S++ K +T+L + ++ +E+Q LI Sbjct: 1603 SQDQQKFNEATQTIKQNEQEYLNLKKQLDDVVSKNNKLETELYEKSQQIQIRGNENQELI 1662 Query: 919 VQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEA---QLQEYKNNIENLN 975 +K + LE + + ++ + +K+ E TQL+ QL+ K + E LN Sbjct: 1663 QNLQKNNQQLEQDILDYKKKEDELNLLIKDLQQKSSEKETQLQINFNQLESLKIDNEKLN 1722 Query: 976 MNVEELNKMNLEL---IDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKI 1032 +++ N+ N ++ + + + K Q ++ ++ +++I+K +I++ QKI Sbjct: 1723 TTIDQQNQDNQKINASMQETINKLQKENEQLQKELMDKISKFQT-------QIMSQEQKI 1775 Query: 1033 NNAQVSYMSMVSDYESK---LAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQD 1089 + Y+ + + + + +L+ +E+ Q + +L + + +L + E + Sbjct: 1776 TQSDEDYLLLQEELNQQNILIQDLQNELKIQQEKNQELILKLNEQQSEYAKLIEVSGESE 1835 Query: 1090 DQIKELK--ETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEE 1147 +++K+ + ++ L N E I+ +E + +N++ +QE Sbjct: 1836 EKVKKSRKEQSNLQVSYNEVLNEKNILLQKLEELHQQ-SNINLKNYEVTKQSLDQVIQER 1894 Query: 1148 EEFIQERSVLQEQSAKL-NTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQL 1206 ++ +Q Q KL L + Q + +++ ++ + + K K+EQ+ Sbjct: 1895 QQLENANQTMQNQIKKLEENHLAQSKNYEDQSQNFKNQVSQLELELENERESNKKKVEQI 1954 Query: 1207 NTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFE- 1265 +N + +L I S + ++ I ++ K Q E D +K E+ +++L+ Sbjct: 1955 QLGYEN---QIVKLEKQIESLIGEKEILIEQVNK---VQEERDIEKNENLKKIELNQINI 2008 Query: 1266 SKYEQLLDSVQSSTQEETNKIV-TMEQVTSLQNKLQDKEEHLRNLQEKYA---DVINQIE 1321 + +Q ++++Q Q+ + + T++Q + L+ + + + NLQE+ + D + + + Sbjct: 2009 EEKQQKINNLQEEIQQNQEQFMQTIKQKEQIILNLRVQVDDISNLQEQISQLQDALQEKQ 2068 Query: 1322 ILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQ----- 1376 + +IE E + + + KQ +++I NIN+E Q Sbjct: 2069 QIIDQIEKENI---QQIYEETLIQKNELLSINNKLNQEKQELQKAIENINQEIQQKSNQI 2125 Query: 1377 --LKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITL-TQRNDE 1433 L+ + ++ E ++ E +++ ++E Q E+++ L +++ Sbjct: 2126 DHLQTLNNEIKTELEQKNGKIKSQEDQIAENIQNIQVLNTENNQLKEEFSLKLNAYKSEN 2185 Query: 1434 FENVRQQLVEYEK---RIED-LTYEKESELAILRLKMHENANHYETMQKESEIERVKLIE 1489 E + Q +E ++E+ + +KE + +++N N + MQ+E+++ + + IE Sbjct: 2186 IEQINQLTAVFENEKTQLENAIKQQKEINQNLENQVVNQNQNIIK-MQQENQLIQSESIE 2244 Query: 1490 ELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRA 1549 + + TE L KQ E L + + E L Q + N I LQ +++ Sbjct: 2245 KQKREFTE---LLKQQDEKLLNLRNQFEDSKEENQLLREQNEQ---KNQNIQQLQQEIQS 2298 Query: 1550 SSSKIQKHVSFASDTKQGRDEQLDNTMNKE 1579 ++ ++ S + EQ+ N + KE Sbjct: 2299 LQQQLDNLINETSILRTENSEQIQN-LKKE 2327 Score = 148 bits (359), Expect = 1e-33 Identities = 261/1240 (21%), Positives = 551/1240 (44%), Gaps = 158/1240 (12%) Query: 214 TKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSK 273 T++Q ++ + + E E+Q+L IE R+ + E NK + E+S++ Sbjct: 2479 TERQQNELNTQSLQQQFEIC-ERQKL--QIEEIQQRLEDIVEQNKETKNEYNELSVQKMS 2535 Query: 274 LAQELEQXXXXXXXXXXXXXXLAK-----QSIEPSCEEKTE-IEEKGSLEIANMTELTKK 327 L Q E+ L +S S ++K + +++ S +I + K Sbjct: 2536 LEQLFEEQRGEFIKESDRNQKLENAIKNLESENKSLKDKLDNLDQNYSNQILEIENERNK 2595 Query: 328 IELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWS 387 EH N +++ +NK+ + K++ ++ I K ++T +K Sbjct: 2596 CLQYEHENQSLQEKCFSYQNKITELDETKKSLIRQLEEFK--IQIKDEQSTVQTLKLEIQ 2653 Query: 388 QL--SSETL---NQDT-DKKINKN---------EIAKLEMVIQSLNKDLVDKEYVISEKD 432 +L +E L NQD + ++N ++ +L + ++L K I E Sbjct: 2654 KLIKQNEDLQKENQDIIENQVNAQLDILEKQNFDLQQLAQFNNQIKEELKLKIISIEEMS 2713 Query: 433 TXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIH--VGTNTEDVNEIAKVQEQLKQELN 490 +D I +Q + Q+ + S +H V E++ +I EQLKQE Sbjct: 2714 VVIDDLKASKLQQDNQIQIIQQQLQESEQINSQLHSQVENYQENIKQIQDTLEQLKQEKQ 2773 Query: 491 D--EIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFS 548 + + KDL +++ +QI + N + + +N+KL +++ Q+ N Sbjct: 2774 EITNQSEQTEKDLQLEIQKLLQQIEEQNQNFQVQINELSNLGANNKLVIQEKQELQKNIQ 2833 Query: 549 KVSDSNKEIVRLTEE-LHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMEN 607 + D K ++ + L K+ EL + Q + ++ + ++++ IE N Sbjct: 2834 DLKDQLKTTQSNNKQTIQSLQAKIEELTTQI--CQQNELNNQLKSQNQQNIHQ--IEELN 2889 Query: 608 LAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQ 667 + L L+ Q L QEL+ +Q+K +E ++K++ Q Q + + + V L ++ Sbjct: 2890 IKNNFLN--KTLKEQVEQLEQELNSVQEKLEE-KNKISKEQQNQFEAL--QENCVQLNQK 2944 Query: 668 IDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKM 727 I L +K+ I+ L+ ++ ++ L+ ++ K N ++E +D+ + + + Sbjct: 2945 IQDLQLNKQNQEHQIQQLQ-NQLNVFEKENLLQKEQISAKTKEANGLREELDVINSQKNL 3003 Query: 728 SAEKISELLAKINHE------EQSKIQT---QFGIDAKIQERD--LYIENIESELSKYKS 776 + S+ L + + E+++I+ QF +D+ Q + I +ESEL++ K Sbjct: 3004 EQTESSKQLQEFCQQMETITREKNQIKQELEQFQLDSSNQSKSERQQINQLESELAQIKQ 3063 Query: 777 RICR----LEESIAVMEDRRYSLERKADQLGSYLQ-------EKQKAYSE----YTIQED 821 R + LEE+ + + L+++ Q+ S L+ +K+K+ ++ ++ Q + Sbjct: 3064 REQKQKVILEENSKNHKIEKEELQQQIKQVNSVLKAEQENFIQKEKSLNQVIKGHSEQIE 3123 Query: 822 ELVNRLAVLMDHDRVVEKQL----LEIEHENKELQKKNQILLEENQ---------NLQIS 868 +L N L + + +++ L+++++ ++ Q+ +Q +++ NQ N++I Sbjct: 3124 QLSNEQKALQNQLNLKNQEIAGLILQMKNKEEQQQQLSQKIVQLNQDISNITEQSNIKIQ 3183 Query: 869 -----LSDMQQHYNALVEKAN--------RTDLAESESTKYQTQLRDLESNLKRITH--- 912 + ++Q+ N+ EK N + +S +++YQ ++ L+ NL++ T+ Sbjct: 3184 NGEKLIEELQELNNSNHEKLNDLESKLKAQQQTIKSSASEYQKNIKQLQDNLQKQTNVNS 3243 Query: 913 -------EHQTLIVQKKKEIEDLEIE---FNTQIESAIRDKKVLNEKYEKNIEYVTQLEA 962 E+ LI QK K++E++ + ++Q + +++N+KY++ + + QL Sbjct: 3244 ELEKQNQENLKLIKQKDKQLEEINTQKEKMSSQYQEEKEQSQIINKKYQQQDQELKQLLV 3303 Query: 963 QLQEYKNN---IENLNMNVEE-----LNKMN-LEL----IDKHVQKQQTQSPDYTEQYIN 1009 +L+ Y+ I+N +NVEE ++ N LE+ +++H+++ Q + T+++ N Sbjct: 3304 KLENYEKQEQEIKNKLINVEEEKSKLIDSQNILEVKVLNLEEHIKRIQEEHSCKTKEFEN 3363 Query: 1010 EINKL---NALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQR 1066 + N+L N LL ++ + + ++ Q ++++ E + + + ++N+EE Sbjct: 3364 KQNELLQSNTLLSKQSANLEDVYKQFELKQNDLLNLIQLLEKEKQEKESAIQNLEE---- 3419 Query: 1067 VSKQLLD-SKQHNEELQILVREQDDQI---KELKETKLTFEMNIPKTEGMIISST--IEP 1120 + KQL+ +KQ+ E+L + +Q+ KEL +K+ E + + + I +T Sbjct: 3420 IKKQLISQNKQNQEKLNQAEADLKNQVQLNKELDNSKIQLEKMLSELQNKIEQNTQNANS 3479 Query: 1121 MSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLET 1180 M D + K + +E +S ++ Q K++ ELQ +I + E Sbjct: 3480 MKDQLKKLQIQVDDQNKQINSEKAKADEL----KSTIENQVQKIS-ELQNKNNQISK-EL 3533 Query: 1181 LNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWK 1240 + + D+ +EQ N K LEQ EN N + E + V EI +L K Sbjct: 3534 NQEKASAQDL--KEQFNNQKLVLEQQQKENINTSNNFKETNKQLQEQVKLLQSEINQL-K 3590 Query: 1241 QHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSST--QEE----TNKIVTMEQVTS 1294 Q Q + K + EL Q+S E ++ + S+ QE+ ++K + EQV Sbjct: 3591 Q---QNDKLNDKHQKELLTQVSILEELQSKIKSQTEQSSNYQEQIKQLSDKNIQNEQVID 3647 Query: 1295 --------LQNKLQDKEEHLRNLQEKYADVINQIEILRSE 1326 L+ K ++E + L Y + +NQ+E+ +SE Sbjct: 3648 QLLCKSKDLETKFILEQEENQKLVNDYEEKMNQLELAKSE 3687 Score = 123 bits (296), Expect = 5e-26 Identities = 277/1549 (17%), Positives = 629/1549 (40%), Gaps = 110/1549 (7%) Query: 55 ERAQKCLENAALVSKRIKEHRKATAELLGRPFVPGISESLANTLKQKEILMEKIKQYKE- 113 E +K L+N ++K +++ ++ E + + E + +T++ ++E+IK+ +E Sbjct: 288 ESIRKELDNLIKINKSLQQDKEYQIEENSK-----LEEEIKSTIEIYTKMIEQIKESQED 342 Query: 114 -LSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNALSVLQVKMKIMETTI 172 K + +++ V L + N + L+ + +M+ T+ Sbjct: 343 NFHKNVNQSMILDQSLQVVYQIKEDNDLKRKVKVLMTDKEALQNKIKNLEFENNMMKQTM 402 Query: 173 LDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEW 232 + +E + QI+ A N+ + +Q++ + F E ++ Sbjct: 403 IVPEEA---RSQILRATNQIKNGQEQIQELRRQIKQLEAQLREQKLNESFSEFRIYEQKY 459 Query: 233 KDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXX 292 K+EK K E I+ L++ + + A +I + S + + Sbjct: 460 KEEKILTTKLQEE----IALLKQGFQT-QGATSQILTQKSDMQSRMIGSKKIKGIASQSN 514 Query: 293 XXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATM 352 + S + + + + EI ++ +L L++ + +++ N L+ +++ + Sbjct: 515 IQMPPLSQTLNVQGIKQSSSNSNQEIESLKKLNDS--LIKEIE-NLKRENSNLQVQVSRI 571 Query: 353 GTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEM 412 +SK+ + +++ + L + K +S+++SP SQ D + A+ + Sbjct: 572 NYDSKSSQNTAQRPNHLQNTKKPIQISSQLQSPVSQFKFG--GSDNANSNSNYHSAEKNL 629 Query: 413 VIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNT 472 ++ + + D + + + TLI Q ++++ + Sbjct: 630 DNKNQQQIINDLQTELEITKNQLKKIMQADSARKTLITQFDQTTNENLQN----QIIQKD 685 Query: 473 EDVNEIAKVQEQLKQEL-------NDEIKDVNVKDLIEK---LKSAEEQITQLNDEIDAA 522 +N + K + LK E N E+ +N ++E L ++ Q T ++ Sbjct: 686 ITINHLQKQLQMLKNEKDFNPNQGNLEMSFLNQSSILEDDLILPTSHGQQT-FRFYQESK 744 Query: 523 NKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTE----ELHHLSQKVAELEEE- 577 K +I N K+++ Q+Q +++ K + I+ TE E +L KV L++E Sbjct: 745 EKEII----NLKMQIDQLQ-SMNRQKKENIMGLSILEDTEAIKSENAYLKAKVESLQKEL 799 Query: 578 --KGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQ 635 K N++ H + DS + ++ E+ + + +L++ + + +L Sbjct: 800 QNKFNVKQHQAELDSLLQSNKKLIQENSELSQKNRKLMDELDILKNSSYSKI-DLSNAYD 858 Query: 636 KYDEVEDKLADI-SQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYG 694 + +E+E+ + Q + +Q+ ++ E + + ++ ++ + ++ Sbjct: 859 RGNEIEELQKKLEKQTKINQILNKQMKEMQENHEQVIDLHNQSMSSILNPQSIQQK---N 915 Query: 695 TIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISEL-LAKINHEEQSKIQTQFGI 753 ++ L + I+ + Q N L ++L+ + S+L ++ + + + + Sbjct: 916 SLASLLATNQKIIEENVQLAQMNKKLQEELDSIRNPSHSQLDISNVYEKANEASSLKRKL 975 Query: 754 DAKIQERDLYIENIESELSKYKSRICRLEE---SIAVMEDRRYSLERKADQLGSYLQEKQ 810 D + Q L E +++ Y+ I + + S + + S K+DQL + ++ + Sbjct: 976 DQQTQLNQLLTEQMKNLKENYEKLIEQHQNDSMSNILHQINGGSSPSKSDQLVTVMETNK 1035 Query: 811 KAYSEYTIQED---ELVNRLAVL--MDHDRVVEKQLLEIEHENKELQKKNQILLEENQNL 865 K E D +L++ + +L M H R+ E +N+ L+ K + E N+ L Sbjct: 1036 KLIEEMASLSDMNKKLMDEIEMLRNMSHSRLDISSTFERNGDNEVLKSKLEKQTELNEAL 1095 Query: 866 QISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEI 925 + +M+QHY + + + ++ + ++ + T+ + L S + E L+ +++ I Sbjct: 1096 MQQMKEMKQHYESTLSQQSQQNQVTLQNQQQFTKQKQLFSEQVKKLEE---LLKKQQDRI 1152 Query: 926 EDLEIE-FNTQIESAIRDKKVLNEK-YEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNK 983 E+LE E + Q+ A R EK +N + QL + Q + NL ++L + Sbjct: 1153 EELEKEQADLQLLQAQRMNMESKEKLMNQNKQQFDQLLSTNQRLSEQVLNLQQQNQQLQQ 1212 Query: 984 MNLELIDKHV-QKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSM 1042 EL ++ + Q T + + I +L + E+I+AL+ K+ + + Sbjct: 1213 EVDELRNRSMYQSIMTDRSSIQIAHNDRIEQLQEENRILSEQIVALS-KVQRNSLPPIEG 1271 Query: 1043 VSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTF 1102 S A L+ E + RV+++LL E ++ ++ + + +K + ++ Sbjct: 1272 NSTVSKNEAIKLHDLQEQNERILRVNQKLLTENLQKGEKEVHMKRELEDLKSRSQLSMSM 1331 Query: 1103 EMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSA 1162 + E + ++ E+E +E L+ + Sbjct: 1332 SYIHDEEEQSKLRKILQEQVLSYEIEIKQVQNELQESKKQFSHEKESLNKEIQQLKNNAH 1391 Query: 1163 KLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRS 1222 LN ++QE +I Q+E L T+ + I LK+++ QLN E + +L+ Sbjct: 1392 LLNQQVQEKEIQIKQIENLTTQNIQKQYQYENAI--LKAQIIQLNEE-----ISQQKLKC 1444 Query: 1223 SISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQL-LDSVQSSTQE 1281 S ++ EI +L Q Q + E + + E + +QL L+ + Sbjct: 1445 ENISKQNENSQEI----NLNLIQ----LQDSLKEKEILIINLEDQVKQLQLEKNKLFQSS 1496 Query: 1282 ETNKIVTMEQVTSLQNKLQDKEEHLRN-LQEKYADVINQIEILRSEIE----DEKVAFXX 1336 E K++ +QV L+ Q + E L+N L + D+ NQ+ L + E Sbjct: 1497 EELKVIHSQQVNQLKLSSQQQCEQLKNELNTQILDLQNQVNQLLQKNERLANQNSEYIQD 1556 Query: 1337 XXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXR-V 1395 + E Q + Q+Q ++ + E Q K++ + + Sbjct: 1557 QQEKENLERQLKEMSEQIEQQEQEIQQQQQLIELLHEQIQEKENIISQDQQKFNEATQTI 1616 Query: 1396 NDAEAKVLELTHQLE-------LKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRI 1448 E + L L QL+ ++E+Y+K+ + I + + +N+++ + E+ I Sbjct: 1617 KQNEQEYLNLKKQLDDVVSKNNKLETELYEKSQQIQIRGNENQELIQNLQKNNQQLEQDI 1676 Query: 1449 EDLTYEKESELAILRLKMHENANHYETMQK--ESEIERVKL-IEELNVKITESVSLNKQV 1505 D +KE EL +L + + ++ ET + +++E +K+ E+LN I + N+ Sbjct: 1677 LDYK-KKEDELNLLIKDLQQKSSEKETQLQINFNQLESLKIDNEKLNTTIDQQ---NQDN 1732 Query: 1506 AELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKI 1554 ++N +++E + N++Q EN++++ L D+I+ Q + + KI Sbjct: 1733 QKINASMQETI---NKLQK--ENEQLQ-KELMDKISKFQTQIMSQEQKI 1775 Score = 99.1 bits (236), Expect = 9e-19 Identities = 245/1243 (19%), Positives = 518/1243 (41%), Gaps = 117/1243 (9%) Query: 398 TDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQL-QLEH 456 TDK+ +N+I LE + + ++ E S+ L Q+ QLE Sbjct: 379 TDKEALQNKIKNLEFENNMMKQTMIVPEEARSQILRATNQIKNGQEQIQELRRQIKQLEA 438 Query: 457 QQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLN 516 Q + L + + K ++ L +L +EI +K + + + +TQ + Sbjct: 439 Q--LREQKLNESFSEFRIYEQKYKEEKILTTKLQEEI--ALLKQGFQTQGATSQILTQKS 494 Query: 517 DEIDA--ANKNMIKVKSNHKLKLKQMQKTIDNFS---KVSDSNKEIVRLTEELHHLSQKV 571 D +K + + S +++ + +T++ S+SN+EI L + L +++ Sbjct: 495 DMQSRMIGSKKIKGIASQSNIQMPPLSQTLNVQGIKQSSSNSNQEIESLKKLNDSLIKEI 554 Query: 572 AELEEEKGNLQLHL--VDYDS-------GRMIESDVYKKMIEMENLAETRLKAISLLESQ 622 L+ E NLQ+ + ++YDS R KK I++ + ++ + S Sbjct: 555 ENLKRENSNLQVQVSRINYDSKSSQNTAQRPNHLQNTKKPIQISSQLQSPVSQFKFGGSD 614 Query: 623 KFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELA--- 679 + H ++ D +++ I+ LQ++ EI L++ + A SA K + Sbjct: 615 NANSNSNYHSAEKNLDN-KNQQQIINDLQTE---LEITKNQLKKIMQADSARKTLITQFD 670 Query: 680 -LVIENLKLDKEQLYGTIKDLENDKEDIMNKLQ-NYIQENMDLTDKLEKMSAEKISELLA 737 ENL+ Q TI L+ + + N+ N Q N++++ + E +L+ Sbjct: 671 QTTNENLQNQIIQKDITINHLQKQLQMLKNEKDFNPNQGNLEMSFLNQSSILE--DDLIL 728 Query: 738 KINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICR---LEESIAVMEDRRY- 793 +H +Q+ Q + +I + I+ ++S + K I LE++ A+ + Y Sbjct: 729 PTSHGQQTFRFYQESKEKEIINLKMQIDQLQSMNRQKKENIMGLSILEDTEAIKSENAYL 788 Query: 794 -----SLERKAD----------QLGSYLQEKQKAY---SEYTIQEDELVNRLAVLMD--H 833 SL+++ +L S LQ +K SE + + +L++ L +L + + Sbjct: 789 KAKVESLQKELQNKFNVKQHQAELDSLLQSNKKLIQENSELSQKNRKLMDELDILKNSSY 848 Query: 834 DRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANR--TDLAES 891 ++ + +E +ELQKK + + NQ L + +MQ+++ +++ N+ + + Sbjct: 849 SKIDLSNAYDRGNEIEELQKKLEKQTKINQILNKQMKEMQENHEQVIDLHNQSMSSILNP 908 Query: 892 ESTKYQTQLRDLESNLKRITHEHQTLIVQKKK---EIEDLEIEFNTQIE-SAIRDKKVLN 947 +S + + L L + ++I E+ L KK E++ + ++Q++ S + +K Sbjct: 909 QSIQQKNSLASLLATNQKIIEENVQLAQMNKKLQEELDSIRNPSHSQLDISNVYEKANEA 968 Query: 948 EKYEKNIEYVTQLEAQLQEYKNNI-ENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQ 1006 ++ ++ TQL L E N+ EN +E+ ++ I H Q SP ++Q Sbjct: 969 SSLKRKLDQQTQLNQLLTEQMKNLKENYEKLIEQHQNDSMSNI-LH-QINGGSSPSKSDQ 1026 Query: 1007 YIN--EINKL----NALLKQKDEEIIALNQKINNAQVSYMSMVSDYE--SKLAQFTTKLE 1058 + E NK A L +++++ + + N S + + S +E +KLE Sbjct: 1027 LVTVMETNKKLIEEMASLSDMNKKLMDEIEMLRNMSHSRLDISSTFERNGDNEVLKSKLE 1086 Query: 1059 NMEEEMQRVSKQLLDSKQHNEELQILVREQDDQI-----KELKETKLTFEMNIPKTEGMI 1113 E + + +Q+ + KQH E + + Q +Q+ ++ + K F + K E ++ Sbjct: 1087 KQTELNEALMQQMKEMKQHYES-TLSQQSQQNQVTLQNQQQFTKQKQLFSEQVKKLEELL 1145 Query: 1114 --ISSTIEPMSDDANNVDXXXXXXXXXXXXLKV--QEEEEFIQERSV----------LQE 1159 IE + + ++ K+ Q +++F Q S LQ+ Sbjct: 1146 KKQQDRIEELEKEQADLQLLQAQRMNMESKEKLMNQNKQQFDQLLSTNQRLSEQVLNLQQ 1205 Query: 1160 QSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAE 1219 Q+ +L E+ E + + +++ T+ + + + ++I QL+ + ++ +E LS V Sbjct: 1206 QNQQLQQEVDELRNRSM-YQSIMTDRSSIQIAHNDRIEQLQEE-NRILSEQIVALSKVQ- 1262 Query: 1220 LRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSST 1279 R+S+ E K H Q ++ E LRV ++ + Sbjct: 1263 -RNSLPPIEGNSTVSKNEAIKLHDLQ-----EQNERILRVNQKLLTENLQK--GEKEVHM 1314 Query: 1280 QEETNKIVTMEQVTSLQNKLQDKEEH--LRN-LQEKYADVINQIEILRSEIEDEKVAFXX 1336 + E + + Q++ + + D+EE LR LQE+ +I+ +++E+++ K F Sbjct: 1315 KRELEDLKSRSQLSMSMSYIHDEEEQSKLRKILQEQVLSYEIEIKQVQNELQESKKQFSH 1374 Query: 1337 XXXXXXXXXXXXXXDLRTENQSY--KQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXR 1394 + NQ K++Q + I N+ +N Q K + Sbjct: 1375 EKESLNKEIQQLKNNAHLLNQQVQEKEIQIKQIENLTTQNIQ--KQYQYENAILKAQIIQ 1432 Query: 1395 VNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYE 1454 +N+ E +L + K +E + E + L Q D + ++ E +++ L E Sbjct: 1433 LNE-EISQQKLKCENISKQNE---NSQEINLNLIQLQDSLKEKEILIINLEDQVKQLQLE 1488 Query: 1455 KESEL-AILRLK-MHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKAL 1512 K + LK +H + + + + E++K ELN +I + + Q+ + N+ L Sbjct: 1489 KNKLFQSSEELKVIHSQQVNQLKLSSQQQCEQLK--NELNTQILDLQNQVNQLLQKNERL 1546 Query: 1513 EEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQ 1555 + ++ + Q EN E ++ ++++I + ++ I+ Sbjct: 1547 ANQNSEYIQDQQEKENLERQLKEMSEQIEQQEQEIQQQQQLIE 1589 Score = 96.3 bits (229), Expect = 6e-18 Identities = 166/872 (19%), Positives = 379/872 (43%), Gaps = 73/872 (8%) Query: 153 EKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXE 212 EK+N L Q+ K E L+E++ D I KN T Sbjct: 2970 EKENLLQKEQISAKTKEAN--GLREEL---DVINSQKNLEQTESSKQLQEFCQQMETITR 3024 Query: 213 DTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANK-LLEAARFEISLEH 271 + Q ++++ + + K E+Q++ +ES+ +I E+ K +LE +E Sbjct: 3025 EKNQIKQELEQFQLDSSNQSKSERQQI-NQLESELAQIKQREQKQKVILEENSKNHKIEK 3083 Query: 272 SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELL 331 +L Q+++Q K + +IE+ + + A +L K + + Sbjct: 3084 EELQQQIKQVNSVLKAEQENFIQKEKSLNQVIKGHSEQIEQLSNEQKALQNQLNLKNQEI 3143 Query: 332 EHLNCQIR---QTNKELENKLATMGTESKAVSSPS----KKGSPLISRKSGRNTASKMKS 384 L Q++ + ++L K+ + + ++ S + G LI N ++ K Sbjct: 3144 AGLILQMKNKEEQQQQLSQKIVQLNQDISNITEQSNIKIQNGEKLIEELQELNNSNHEKL 3203 Query: 385 PWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXG 444 + L S+ Q K + +E K I+ L +L + V SE + Sbjct: 3204 --NDLESKLKAQQQTIKSSASEYQKN---IKQLQDNLQKQTNVNSELEKQNQENLKLIKQ 3258 Query: 445 KDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEK 504 KD + ++ + ++ + + ++ E +++ + Q+ + E+K + VK +E Sbjct: 3259 KDKQLEEINTQKEK---------MSSQYQEEKEQSQIINKKYQQQDQELKQLLVK--LEN 3307 Query: 505 LKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKV-SDSNKEIVRLTEE 563 + E++I ++ +I ++ ++K+ +++ I + S KE E Sbjct: 3308 YEKQEQEIKNKLINVEEEKSKLIDSQNILEVKVLNLEEHIKRIQEEHSCKTKEFENKQNE 3367 Query: 564 LHH----LSQKVAELEEEKGNLQLHLVDY-DSGRMIESDVYKKMIEMENLAETRLKAISL 618 L LS++ A LE+ +L D + +++E + +K ++NL E + + IS Sbjct: 3368 LLQSNTLLSKQSANLEDVYKQFELKQNDLLNLIQLLEKEKQEKESAIQNLEEIKKQLISQ 3427 Query: 619 LESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASK--- 675 + + L Q L+ + +K D S++Q +++ SE+++ +E+ ++ K Sbjct: 3428 NKQNQEKLNQAEADLKNQVQL--NKELDNSKIQLEKMLSELQN-KIEQNTQNANSMKDQL 3484 Query: 676 KELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKL--EKMSAEKIS 733 K+L + +++ +L++ E+ + K+ +N ++ +L EK SA+ + Sbjct: 3485 KKLQIQVDDQNKQINSEKAKADELKSTIENQVQKISELQNKNNQISKELNQEKASAQDLK 3544 Query: 734 ELL--AKINHEEQSK--IQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEES----- 784 E K+ E+Q K I T ++ ++ ++SE+++ K + +L + Sbjct: 3545 EQFNNQKLVLEQQQKENINTSNNFKETNKQLQEQVKLLQSEINQLKQQNDKLNDKHQKEL 3604 Query: 785 ---IAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQL 841 ++++E+ + ++ + +Q +Y QE+ K S+ IQ ++++++L L + K + Sbjct: 3605 LTQVSILEELQSKIKSQTEQSSNY-QEQIKQLSDKNIQNEQVIDQL--LCKSKDLETKFI 3661 Query: 842 LEIEHENKEL-----QKKNQILLEENQNLQISLSDMQQHYNALVEKANRTD-LAESESTK 895 LE E EN++L +K NQ+ L +++ + + +Q + E N + ESE + Sbjct: 3662 LEQE-ENQKLVNDYEEKMNQLELAKSEEVNSLIEQFKQEKSLWNELKNEENGKIESERNE 3720 Query: 896 YQTQLRDLESNLKRIT-------HEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNE 948 +T++ +L +K + E T+ K+E++ +++E QIE + K L + Sbjct: 3721 LKTKMFELFEQVKVLQMVVSDKESEINTIKQSHKEELDQIQLEKQKQIEQLAQQKSNLAQ 3780 Query: 949 KYEKNIEYVTQLEAQLQEYKNNIENLNMNVEE 980 + + + +L+ ++ +++ + + +E+ Sbjct: 3781 QIFELTNQLQKLQEEIDLNRSSYSHNSSMIED 3812 Score = 66.1 bits (154), Expect = 8e-09 Identities = 145/772 (18%), Positives = 324/772 (41%), Gaps = 76/772 (9%) Query: 837 VEKQLLEIEHENKELQKKNQILLEENQNLQISL---SDMQQHYNALVEKANRTDLAESES 893 V +Q+ H N L + N+N+ I++ S QQ+ + N+ ++++++ Sbjct: 224 VTEQIYSFLHRNNALPISSSSTYASNENITIAIQMDSRTQQNSLEVWNDRNQQNISQTDV 283 Query: 894 TKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKN 953 +R NL +I +Q+ KE +IE N+++E E+ + Sbjct: 284 FLLMESIRKELDNLIKINKS-----LQQDKE---YQIEENSKLE----------EEIKST 325 Query: 954 IEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINK 1013 IE T++ Q++E + + + N+N + +L+++ + K+ + + + Sbjct: 326 IEIYTKMIEQIKESQEDNFHKNVNQSMILDQSLQVV--YQIKEDNDLKRKVKVLMTDKEA 383 Query: 1014 LNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQL-- 1071 L +K + E NN M + + S++ + T +++N +E++Q + +Q+ Sbjct: 384 LQNKIKNLEFE--------NNMMKQTMIVPEEARSQILRATNQIKNGQEQIQELRRQIKQ 435 Query: 1072 LDSKQHNEEL-----QILVREQDDQIKELKETKLTFEMNIPK----TEGMIISSTIEPMS 1122 L+++ ++L + + EQ + +++ TKL E+ + K T+G + Sbjct: 436 LEAQLREQKLNESFSEFRIYEQKYKEEKILTTKLQEEIALLKQGFQTQGATSQILTQKSD 495 Query: 1123 DDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECY----TKIIQL 1178 + + +++ + + + + ++ S+ N E++ + I ++ Sbjct: 496 MQSRMIGSKKIKGIASQSNIQMPPLSQTLNVQGI-KQSSSNSNQEIESLKKLNDSLIKEI 554 Query: 1179 ETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTV---AELRSSISSAVDQRGFEI 1235 E L E + V +IN SK Q + N L ++ S + S V Q F Sbjct: 555 ENLKRE-NSNLQVQVSRIN-YDSKSSQNTAQRPNHLQNTKKPIQISSQLQSPVSQFKFGG 612 Query: 1236 AELWKQ----HLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQ 1291 ++ H A++ D + + + + E QL +Q+ + +T I +Q Sbjct: 613 SDNANSNSNYHSAEKNLDNKNQQQIINDLQTELEITKNQLKKIMQADSARKT-LITQFDQ 671 Query: 1292 VT--SLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXX 1349 T +LQN++ K+ + +LQ++ + N+ + ++ + +++F Sbjct: 672 TTNENLQNQIIQKDITINHLQKQLQMLKNEKDFNPNQ-GNLEMSFLNQSSILEDDLILPT 730 Query: 1350 XDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQL 1409 + + Y++ +E+ I+N+ + QL +S + D EA E + L Sbjct: 731 SHGQQTFRFYQESKEKEIINLKMQIDQL-QSMNRQKKENIMGLSILEDTEAIKSENAY-L 788 Query: 1410 ELKDSEIYQKTHEYTITLTQRNDEFENVRQ---QLVEYEKRIEDLTYEKESELAILRLKM 1466 + K E QK + + Q E +++ Q +L++ + + EL IL+ Sbjct: 789 KAK-VESLQKELQNKFNVKQHQAELDSLLQSNKKLIQENSELSQKNRKLMDELDILKNSS 847 Query: 1467 HENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNE-MQTA 1525 + + + +EIE ++ E KI + LNKQ+ E+ + E+ + N+ M + Sbjct: 848 YSKIDLSNAYDRGNEIEELQKKLEKQTKINQ--ILNKQMKEMQENHEQVIDLHNQSMSSI 905 Query: 1526 LENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMN 1577 L Q I+ + +L +++ + I+++V A K+ E+LD+ N Sbjct: 906 LNPQSIQ------QKNSLASLLATNQKIIEENVQLAQMNKK-LQEELDSIRN 950 >UniRef50_UPI0000D8E0D3 Cluster: UPI0000D8E0D3 related cluster; n=1; Danio rerio|Rep: UPI0000D8E0D3 UniRef100 entry - Danio rerio Length = 2074 Score = 185 bits (450), Expect = 1e-44 Identities = 260/1477 (17%), Positives = 649/1477 (43%), Gaps = 91/1477 (6%) Query: 143 DVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXX 202 ++T + IK ++ ++ Q ++ ++T I +LQ+++ ++ +II Sbjct: 450 NITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEIIMKDRSQLDLRQSELDK 509 Query: 203 XXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSL-EEANKLLE 261 E K + ++ ++ ME E K E +++ ++E + IS + EE E Sbjct: 510 QQTNMNDIMETMKNERKQLDKDKEEME-EQKQEMEKMKIELEREADEISKIKEETQNKNE 568 Query: 262 AARFEISLEHSKL-AQELEQXXXXXXXXXXXXXXLAKQSIE--PSCEEKTEIEEKGSLEI 318 + ++ +H + +E+ L + IE +E +I+E+ E Sbjct: 569 IEKIKLETQHDRQRVEEMAAQIQKKQVFEEEKNKLEQMKIELEREADEIRKIKEETQNER 628 Query: 319 ANMTELTKKIELLEHLNCQIRQTNKELEN-KLATMGTESKA-------VSSPSKKGSPLI 370 ++ ++T++++ E + ++ + E+E KL T + + + + + L Sbjct: 629 QSLEKMTEELKK-EKMKTELEREADEIEKIKLETQHERQRVEEMTADFMETMNNERKQLD 687 Query: 371 SRKSG-RNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKD-----LVDK 424 K +M+ S+ + N+ K+ ++E+ KL+ +Q K +DK Sbjct: 688 KNKVMIEEQKQEMRENISKQIEDIENEKEKSKLREDELKKLQTEVQKQQKRDSESLKLDK 747 Query: 425 EYVISEKDTXXXXXXXXXXGKDTLIA-QLQLEHQQHMEGPSLIHVGTNTEDVNEIAKV-- 481 E +EK+ D + +L+ H++ + E++N + + Sbjct: 748 EAFENEKEAMKQMKTDLQIQADEIEKIKLETHHERQRVEEKTAQIQKEREEINTLVEENQ 807 Query: 482 QEQLKQELNDEIKD-VNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLK---L 537 QE+ K+ + + K+ ++++ + + E ++ +L ++I + M ++K+ ++ L Sbjct: 808 QEKNKKTITEMQKERETLEEMRANISNRESELAKLQEDILQQQQEMDELKNTIMMEMCQL 867 Query: 538 KQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESD 597 Q Q ID + +KE+ L + + + A+LE KG LQ+ D + R ++ Sbjct: 868 DQRQSDIDLLQNKLNLHKELEELNLQKQGIQDERAQLERMKGELQMKADDIE--RKMQEI 925 Query: 598 VYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLA-----DISQ--L 650 +Y+K E +E K + L+ + VQ+L+ ++YDE +K DI + Sbjct: 926 LYEKQKYAERKSEN-YKIQTYLDEANAE-VQKLNKELERYDENLEKCKLELDKDIRRNLF 983 Query: 651 QSDQVCSEIKSVHLEEQIDA------LSASKKELALVIENLKLDKEQLYGTIKDLENDKE 704 + ++ + K+ +E + + L S++EL ++ +K + +L + + ++ Sbjct: 984 KKEEAIEKDKAEKIESEREIQQEKKKLQRSEEELEDKMQKIKREMIELKLLQDETDGKRK 1043 Query: 705 DIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSK--IQTQFGIDAKIQERDL 762 D+ NK++ Q+N ++ + +++ + K+ L + N EQ++ ++ Q I A + ++ L Sbjct: 1044 DVDNKMR---QQNDEIQKEKQQIESSKML-LSRERNDLEQNRADLERQKQIMA-LDKQKL 1098 Query: 763 YIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDE 822 EN L + K+ + ++ E++ + + + ER + + +E+ + + +E E Sbjct: 1099 LAEN--ELLEREKADVIKIIENLESLREEA-TRERATETAQATKREELEQLKDEINREKE 1155 Query: 823 LVNRLAVLMDH--DRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALV 880 V L++ D+ K+ +I+ +ELQ + LL + ++L SD+Q + Sbjct: 1156 DVEIRRELVEAVIDKEEMKEFTDIQKYKEELQSVTEELLTKKRDLDQLNSDVQDLRQTIE 1215 Query: 881 EKANRTDLAESESTKYQTQLRDLESN-----LKRITHEHQTLIVQKKKEIEDLEIEFNTQ 935 ++ + + + + + + LE K+ EH T +QK+++I + + + Q Sbjct: 1216 KEKEELEQLKKDINREKEDIETLEEVDIQYIKKKAELEHITSEIQKREQILEKQKKNKNQ 1275 Query: 936 IESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELID-KHVQ 994 IE +D + + E+ +E + +A ++E + +++L M + ++ + E+ D K + Sbjct: 1276 IEQEKKDLQNMKSNLERQLESLRHEKANVEEIELKVKDLEMEMADMKRQKQEIEDTKGLL 1335 Query: 995 KQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFT 1054 +++ Q ++ + + ++ L ++K E ++ N ++ + + D ++ Sbjct: 1336 EKEKQELKQEKKELED--QMMDLTREKQE-----TEEERNNLMALKNQLEDLRKIKSELV 1388 Query: 1055 TKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMII 1114 + ++ E ++++ + +Q E+L+ + E Q +E+++ + N E + Sbjct: 1389 REKTEVDHEQKKLNDDIKMIEQEKEDLEKMKSEIMTQKQEMEKERKEERRN---EETRRL 1445 Query: 1115 SSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTK 1174 +E MS D N + + + + + + RS + + KLN + + + Sbjct: 1446 KEDLEKMSTDVNKQNKDLMNQRDLLEQEREEIKSQLERVRSEIDHEQKKLNDDKKMIEQE 1505 Query: 1175 IIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTEN----------DNLLSTVAELRSSI 1224 LE + +E+ +E+ ++L +K++Q + E L+ V E R I Sbjct: 1506 KEDLEKMKSEIMKQRQQMEEERSELDNKIKQTDLERHDIENSKEIVQKLMVEVEEQRKDI 1565 Query: 1225 SSAVDQRGFEIAELWKQH--LAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEE 1282 ++ E ++ + + Q +A Q E+E ++ K ++ L +++ ++E Sbjct: 1566 RLQKEELDIERQKIADEQGLVVQNKAKLQ-NENERIKEMDEEIKKEKETLKEMEAHLRKE 1624 Query: 1283 TNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXX 1342 ++ ++ + T + K +D E+ ++ ++ D++NQ ++L+ E E+ F Sbjct: 1625 KEEMRSVIEETQRRQK-EDLEKMSTDVNKQNQDLMNQRDLLKQEREERIDEFDAQVSKQK 1683 Query: 1343 XXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKV 1402 + E + ++M+ + I+ ++ + + + + EA + Sbjct: 1684 EEDLTKQKKMEEEKEDLEKMKSE-IMKQRQQMEEERSELENKNEVIKKERETLKEMEAYL 1742 Query: 1403 LELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAIL 1462 + +++ E ++ + T N++ +++R Q E+ E++ + K +L Sbjct: 1743 EKEKEEMKSITEETRRQKEDLEKMSTHINEQKQDLRSQRDLLEQEREEINH-KWKQLQQR 1801 Query: 1463 RLKMHENANHYETMQKESEIERVKLIEELNVKI---TESVSLNKQVAELNKALEEEVAKT 1519 + ++E +IER K+ +E ++ I E + N+++ E+++ +++E Sbjct: 1802 IDEFDAQIKSQLERKEELDIERQKIADEQDLLIQNKIEQQNENERIKEMDEEIKKERETL 1861 Query: 1520 NEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQK 1556 EM+ L+ ++ EI ++ +E + + S+ I + Sbjct: 1862 KEMEVNLQKEKEEIESVIEETQRRKEDLEKMSTDINE 1898 Score = 163 bits (395), Expect = 5e-38 Identities = 280/1475 (18%), Positives = 617/1475 (41%), Gaps = 117/1475 (7%) Query: 147 LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXX 206 LS K K+ L ++V E+T+ D+ + + ++ E +K T Sbjct: 114 LSEDAKRKNQVLDEMKVAN---ESTLADILRERSNLQEMRENISKQTEDVENKKEKIRLR 170 Query: 207 XXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFE 266 + + ++ K Q ++ + E+ ++KD+E +I SL+ + L+ R Sbjct: 171 EEKLKQ-LQAEIHKQQSETEKEKSNIERERAAIIKDVEDLQSKIISLDRDAESLKLDREA 229 Query: 267 ISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTK 326 E +L Q + L K E E+K E+E++ + L K Sbjct: 230 FENEKEELKQMKTELEREAETMNNERKQLNKNKEEMQ-EQKQEMEKERHDMDQSRKSLDK 288 Query: 327 KIELLEHLNCQIRQT---NKELENKLATMGTESKAVSSPSKKGSPLISRKS---GRNTAS 380 +++++ + R KE K E + + + K I ++ A+ Sbjct: 289 NLKMMKLQKQKTRSKLLRAKENLEKQRLREDELRQLQAEIHKQQREIEKEKINIESERAA 348 Query: 381 KMKSPWS-QLSSETLNQDTDK-KINKNEIAKLEMVIQSLNKDLVDK-EYVISEKDTXXXX 437 +K Q L++D + K+++ E + +MV+ N+D+ +K + + S+KD Sbjct: 349 IIKDVEDLQHKIICLDRDAESLKLDREETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKE 408 Query: 438 XXXXXXGKDTLI-AQLQLEHQQ-------HMEGPSLIHVGTN-TEDVNEIAKVQEQL--K 486 + L + LE Q+ E L + N T +++EI +EQ+ K Sbjct: 409 KHDLEKTRSELYKVKEDLEKQKENTLAEIQKEREDLEKMNENITREMHEIKHQEEQMNQK 468 Query: 487 QELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDN 546 Q+ D++K +++L ++L+ +E I + ++D + K ++N + + +T+ N Sbjct: 469 QDELDQLK-TEIQNLQQELEKEKEIIMKDRSQLDLRQSELDKQQTN----MNDIMETMKN 523 Query: 547 FSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEME 606 K D +KE + E+ + + ELE E + + + IE + + + Sbjct: 524 ERKQLDKDKE--EMEEQKQEMEKMKIELEREADEISKIKEETQNKNEIEKIKLETQHDRQ 581 Query: 607 NLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEE 666 + E A + + Q F+ +E + L+Q E+E + +I +++ ++ +E +S LE+ Sbjct: 582 RVEE---MAAQIQKKQVFE--EEKNKLEQMKIELEREADEIRKIK-EETQNERQS--LEK 633 Query: 667 QIDALSASKKELAL-----VIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLT 721 + L K + L IE +KL+ + ++++ D + MN + + +N + Sbjct: 634 MTEELKKEKMKTELEREADEIEKIKLETQHERQRVEEMTADFMETMNNERKQLDKNKVMI 693 Query: 722 DKLEKMSAEKISELL---------AKINHEEQSKIQTQFGIDAKIQERDLYIENIESELS 772 ++ ++ E IS+ + +K+ +E K+QT+ K L ++ E Sbjct: 694 EEQKQEMRENISKQIEDIENEKEKSKLREDELKKLQTEVQKQQKRDSESLKLDKEAFENE 753 Query: 773 KYKSRICRLEESIAVMEDRRYSLE-----RKADQLGSYLQEKQKAYSEYTIQEDELVNRL 827 K + + + I E + LE ++ ++ + +Q++++ + + + N+ Sbjct: 754 KEAMKQMKTDLQIQADEIEKIKLETHHERQRVEEKTAQIQKEREEINTLVEENQQEKNKK 813 Query: 828 AVL-MDHDR-VVEKQLLEIEHENKELQKKNQILLEENQ-------NLQISLSDMQQHYNA 878 + M +R +E+ I + EL K + +L++ Q + + + + Q + Sbjct: 814 TITEMQKERETLEEMRANISNRESELAKLQEDILQQQQEMDELKNTIMMEMCQLDQRQSD 873 Query: 879 LVEKANRTDL-AESESTKYQTQ-LRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQI 936 + N+ +L E E Q Q ++D + L+R+ E Q +++++++ E Sbjct: 874 IDLLQNKLNLHKELEELNLQKQGIQDERAQLERMKGELQMKADDIERKMQEILYEKQKYA 933 Query: 937 ESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQ 996 E + K+ E N E V +L +L+ Y N+E + +++ + NL ++ ++K Sbjct: 934 ERKSENYKIQTYLDEANAE-VQKLNKELERYDENLEKCKLELDKDIRRNLFKKEEAIEKD 992 Query: 997 QTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTK 1056 + + + +E+ EI + L++ +EE+ QKI + + + + K K Sbjct: 993 KAEKIE-SER---EIQQEKKKLQRSEEELEDKMQKIKREMIELKLLQDETDGKRKDVDNK 1048 Query: 1057 LENMEEEMQR------VSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTE 1110 + +E+Q+ SK LL ++++ E E+ QI L + KL E + + E Sbjct: 1049 MRQQNDEIQKEKQQIESSKMLLSRERNDLEQNRADLERQKQIMALDKQKLLAENELLERE 1108 Query: 1111 GMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQE 1170 + IE + ++ + K +EE E +++ +++ ++ EL E Sbjct: 1109 KADVIKIIENL--ESLREEATRERATETAQATK-REELEQLKDEINREKEDVEIRRELVE 1165 Query: 1171 CYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTEN---DNLLSTVAELRSSISSA 1227 +I E + E T D+ Q+ +L+S E+L T+ D L S V +LR +I Sbjct: 1166 A---VIDKEEMK-EFT--DI--QKYKEELQSVTEELLTKKRDLDQLNSDVQDLRQTIEKE 1217 Query: 1228 VDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQ----EET 1283 + E+ +L K RE + +T E+ +Q +++ E + +Q Q ++ Sbjct: 1218 KE----ELEQLKKD--INREKEDIETLEEVDIQYIKKKAELEHITSEIQKREQILEKQKK 1271 Query: 1284 NKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXX 1343 NK ++ LQN + E L +L+ + A+V +IE+ ++E E Sbjct: 1272 NKNQIEQEKKDLQNMKSNLERQLESLRHEKANV-EEIELKVKDLEMEMADMKRQKQEIED 1330 Query: 1344 XXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVL 1403 + + Q K++++Q ++++ E K+ + ++ D Sbjct: 1331 TKGLLEKEKQELKQEKKELEDQ-MMDLTRE----KQETEEERNNLMALKNQLEDLRKIKS 1385 Query: 1404 ELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILR 1463 EL + D E +K ++ + Q ++ E ++ +++ ++ +E E+ R Sbjct: 1386 ELVREKTEVDHE-QKKLNDDIKMIEQEKEDLEKMKSEIMTQKQEMEKERKEERRNEETRR 1444 Query: 1464 LKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQ 1523 LK E M + + L+ + ++ E + Q+ + ++ E K N+ + Sbjct: 1445 LK-----EDLEKMSTDVNKQNKDLMNQRDLLEQEREEIKSQLERVRSEIDHEQKKLNDDK 1499 Query: 1524 TALENQEIEIVTLNDEITNLQNMVRASSSKIQKHV 1558 +E ++ ++ + EI + + S++ + Sbjct: 1500 KMIEQEKEDLEKMKSEIMKQRQQMEEERSELDNKI 1534 Score = 159 bits (387), Expect = 4e-37 Identities = 243/1181 (20%), Positives = 534/1181 (45%), Gaps = 116/1181 (9%) Query: 220 KMQENFIAME--AEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQE 277 KMQE + AE K E ++ ++ + + L NK LE R++ +LE KL E Sbjct: 921 KMQEILYEKQKYAERKSENYKIQTYLDEANAEVQKL---NKELE--RYDENLEKCKL--E 973 Query: 278 LEQXXXXXXXXXXXXXXLAK-QSIEPSCE---EKTEIEEKGSLEIANMTELTKKIELLEH 333 L++ K + IE E EK +++ M ++ +++ L+ Sbjct: 974 LDKDIRRNLFKKEEAIEKDKAEKIESEREIQQEKKKLQRSEEELEDKMQKIKREMIELKL 1033 Query: 334 LNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSET 393 L + K+++NK+ E + + L+SR+ RN + ++ + + Sbjct: 1034 LQDETDGKRKDVDNKMRQQNDEIQKEKQQIESSKMLLSRE--RNDLEQNRADLER-QKQI 1090 Query: 394 LNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQ 453 + D K + +NE+ + E + K +++ + E+ T K + QL+ Sbjct: 1091 MALDKQKLLAENELLEREKA--DVIK-IIENLESLREEATRERATETAQATKREELEQLK 1147 Query: 454 LEHQQHMEGPS----LIHVGTNTEDVNE---IAKVQEQLK---QELNDEIKDVN-----V 498 E + E L+ + E++ E I K +E+L+ +EL + +D++ V Sbjct: 1148 DEINREKEDVEIRRELVEAVIDKEEMKEFTDIQKYKEELQSVTEELLTKKRDLDQLNSDV 1207 Query: 499 KDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIV 558 +DL + ++ +E++ QL +I+ +++ ++ +K+ + S++ + + Sbjct: 1208 QDLRQTIEKEKEELEQLKKDINREKEDIETLEEVDIQYIKKKAELEHITSEIQKREQILE 1267 Query: 559 RLTEELHHLSQKVAELEEEKGNL--QLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAI 616 + + + + Q+ +L+ K NL QL + ++ + E ++ K +EME R K Sbjct: 1268 KQKKNKNQIEQEKKDLQNMKSNLERQLESLRHEKANVEEIELKVKDLEMEMADMKRQK-- 1325 Query: 617 SLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKK 676 +E K L +E L+Q+ E+ED++ D+++ + + + L+ Q++ L K Sbjct: 1326 QEIEDTKGLLEKEKQELKQEKKELEDQMMDLTREKQETEEERNNLMALKNQLEDLRKIKS 1385 Query: 677 ELALVIENLKLDKEQ--LYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISE 734 EL V E ++D EQ L IK +E +KED+ K+++ I +K K E+ +E Sbjct: 1386 EL--VREKTEVDHEQKKLNDDIKMIEQEKEDL-EKMKSEIMTQKQEMEKERK--EERRNE 1440 Query: 735 LLAKINHEEQSKIQTQFGIDAK--IQERDLYI---ENIESELSKYKSRICRLEESIAVME 789 ++ E+ K+ T K + +RDL E I+S+L + +S I ++ + Sbjct: 1441 ETRRLK-EDLEKMSTDVNKQNKDLMNQRDLLEQEREEIKSQLERVRSEIDHEQKKL---N 1496 Query: 790 DRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAV--LMDHD-----RVVEKQLL 842 D + +E++ + L E K + + EL N++ L HD +V+K ++ Sbjct: 1497 DDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDNKIKQTDLERHDIENSKEIVQKLMV 1556 Query: 843 EIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRD 902 E+E + K+++ + + L E Q + + Q+ L + R + E K + L++ Sbjct: 1557 EVEEQRKDIRLQKEELDIERQKIADEQGLVVQNKAKLQNENERIKEMDEEIKKEKETLKE 1616 Query: 903 LESNLKRITHEHQTLIVQ----KKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNI-EYV 957 +E++L++ E +++I + +K+++E + + N Q + + + +L ++ E+ I E+ Sbjct: 1617 MEAHLRKEKEEMRSVIEETQRRQKEDLEKMSTDVNKQNQDLMNQRDLLKQEREERIDEFD 1676 Query: 958 TQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSP-----DYTEQYINEIN 1012 Q+ Q +E + + E+L KM E++ + Q ++ +S + ++ + Sbjct: 1677 AQVSKQKEEDLTKQKKMEEEKEDLEKMKSEIMKQRQQMEEERSELENKNEVIKKERETLK 1736 Query: 1013 KLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLL 1072 ++ A L+++ EE+ ++ ++ + M + + ++ + +E+E + ++ + Sbjct: 1737 EMEAYLEKEKEEMKSITEETRRQKEDLEKMSTHINEQKQDLRSQRDLLEQEREEINHKWK 1796 Query: 1073 DSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXX 1132 +Q +E ++ Q ++ +EL + I + ++I + IE +++ Sbjct: 1797 QLQQRIDEFDAQIKSQLERKEELDIER----QKIADEQDLLIQNKIEQQNENER------ 1846 Query: 1133 XXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQ-------LETLNTEL 1185 +K + +EE +ER L+E L E +E + I + LE ++T++ Sbjct: 1847 ---------IK-EMDEEIKKERETLKEMEVNLQKEKEEIESVIEETQRRKEDLEKMSTDI 1896 Query: 1186 T--GHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVD---QRGFEIAELWK 1240 D++NQ + LK + E++N + L + E ++ + V + E+ E + Sbjct: 1897 NEQKQDLMNQRDL--LKQEREEMNHKLTQLQQRIDEFETTSNILVTTKMEEKTEMDEKLQ 1954 Query: 1241 QHLAQREADFQKTEHELRVQLSAFESKYEQL-LDSVQSSTQEETNK------IVTMEQVT 1293 Q + + E+ ++T + R +L E + + + S ET K + +++V Sbjct: 1955 QAIKEYESIIEETNRK-RTELEEIEKERKDTEKERGCSRGGTETGKKGGEFERIQIDEVK 2013 Query: 1294 SLQNKL-QDKEEHLRNLQ--EKYADVINQIEILRSEIEDEK 1331 + +++ ++K+E RN Q E + + +I+ R EIE K Sbjct: 2014 RILSEIHKEKKELERNKQILEHQREALLEIKKEREEIEKMK 2054 Score = 155 bits (376), Expect = 1e-35 Identities = 284/1516 (18%), Positives = 644/1516 (42%), Gaps = 148/1516 (9%) Query: 151 IKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXX 210 I+E+ + L ++++++ I ++E+ + QI E +A Sbjct: 65 IEEEKSKLKQMKIELEREADEIRKVKEETQNERQIFEKMTEALKKEREDLSEDAKRKNQV 124 Query: 211 XEDTKQQMTKMQENFIAMEAEWKDEKQRLLK---DIESKDVRISSLEEANKLLEAA--RF 265 ++ K + + + ++ ++ + K D+E+K +I EE K L+A + Sbjct: 125 LDEMKVANESTLADILRERSNLQEMRENISKQTEDVENKKEKIRLREEKLKQLQAEIHKQ 184 Query: 266 EISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANM-TEL 324 + E K E E+ ++ S + E E E+ M TEL Sbjct: 185 QSETEKEKSNIERERAAIIKDVEDLQSKIISLDRDAESLKLDREAFENEKEELKQMKTEL 244 Query: 325 TKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLIS--RKSGRNTASKM 382 ++ E + + Q+ + +E++ + M E + K + + + T SK+ Sbjct: 245 EREAETMNNERKQLNKNKEEMQEQKQEMEKERHDMDQSRKSLDKNLKMMKLQKQKTRSKL 304 Query: 383 KSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXX 442 L + L +D +++ EI K + I+ K ++ E KD Sbjct: 305 LRAKENLEKQRLREDELRQLQA-EIHKQQREIEK-EKINIESERAAIIKDVEDLQHKIIC 362 Query: 443 XGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNV-KDL 501 +D L+L+ ++ TN +D+ V + +++ ++IK + KD+ Sbjct: 363 LDRDA--ESLKLDREE-----------TNRKDM-----VLNEKNRDIEEKIKSIQSDKDM 404 Query: 502 IEK----LKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDN-FSKVSDSNKE 556 +EK L+ ++ ++ ++++ +N + + L++M + I ++ ++ Sbjct: 405 LEKEKHDLEKTRSELYKVKEDLEKQKENTLAEIQKEREDLEKMNENITREMHEIKHQEEQ 464 Query: 557 IVRLTEELHHLSQKVAELEEE-KGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKA 615 + + +EL L ++ L++E + ++ + D + +S++ K+ M ++ ET Sbjct: 465 MNQKQDELDQLKTEIQNLQQELEKEKEIIMKDRSQLDLRQSELDKQQTNMNDIMETMKNE 524 Query: 616 ISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSD-QVCSEIKSVHLEEQID----- 669 L+ K ++ ++ +++ E+E + +IS+++ + Q +EI+ + LE Q D Sbjct: 525 RKQLDKDKEEMEEQKQEMEKMKIELEREADEISKIKEETQNKNEIEKIKLETQHDRQRVE 584 Query: 670 --ALSASKKEL----ALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDK 723 A KK++ +E +K++ E+ I+ ++ + ++ L+ +E K Sbjct: 585 EMAAQIQKKQVFEEEKNKLEQMKIELEREADEIRKIKEETQNERQSLEKMTEELKKEKMK 644 Query: 724 LE-KMSAEKISELLAKINHEEQS-KIQTQFGIDAKIQERDLYIEN---IESELSKYKSRI 778 E + A++I ++ + HE Q + T ++ ER +N IE + + + I Sbjct: 645 TELEREADEIEKIKLETQHERQRVEEMTADFMETMNNERKQLDKNKVMIEEQKQEMRENI 704 Query: 779 CRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRV-- 836 + E I +++ E + +L + +Q++QK SE + E M + Sbjct: 705 SKQIEDIENEKEKSKLREDELKKLQTEVQKQQKRDSESLKLDKEAFENEKEAMKQMKTDL 764 Query: 837 ------VEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAE 890 +EK LE HE + +++K + +E + + + + QQ N K T++ + Sbjct: 765 QIQADEIEKIKLETHHERQRVEEKTAQIQKEREEINTLVEENQQEKN----KKTITEMQK 820 Query: 891 SEST--KYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNT---QIESAIRDKKV 945 T + + + + ES L ++ + I+Q+++E+++L+ Q++ D + Sbjct: 821 ERETLEEMRANISNRESELAKLQED----ILQQQQEMDELKNTIMMEMCQLDQRQSDIDL 876 Query: 946 LNEKYE--KNIEYVTQLEAQLQEYKNNIEN----LNMNVEELNKMNLELIDKHVQKQQTQ 999 L K K +E + + +Q+ + +E L M +++ + E++ + + + + Sbjct: 877 LQNKLNLHKELEELNLQKQGIQDERAQLERMKGELQMKADDIERKMQEILYEKQKYAERK 936 Query: 1000 SPDYTEQ-YINEIN----KLNALLKQKDEEI----IALNQKINNAQVSYMSMVSDYESKL 1050 S +Y Q Y++E N KLN L++ DE + + L++ I + +++ Sbjct: 937 SENYKIQTYLDEANAEVQKLNKELERYDENLEKCKLELDKDIRRNLFKKEEAIEKDKAEK 996 Query: 1051 AQFTTKLENMEEEMQRVSKQLLDSKQHNE----ELQILVREQDDQIKELKETKLTFEMNI 1106 + +++ ++++QR ++L D Q + EL++L E D + K++ + K+ + + Sbjct: 997 IESEREIQQEKKKLQRSEEELEDKMQKIKREMIELKLLQDETDGKRKDV-DNKMRQQNDE 1055 Query: 1107 PKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNT 1166 + E I S+ +S + N+++ + + ++++ + E +L+ + A + Sbjct: 1056 IQKEKQQIESSKMLLSRERNDLEQNRADLERQKQIMAL-DKQKLLAENELLEREKADV-- 1112 Query: 1167 ELQECYTKIIQ-LETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSIS 1225 KII+ LE+L E T Q + + +LEQL E + V R + Sbjct: 1113 ------IKIIENLESLREEATRERATETAQATK-REELEQLKDEINREKEDVEIRRELVE 1165 Query: 1226 SAVDQRGF-EIAELWK---------QHLAQREADFQKTEHELRVQLSAFESKYEQLLDSV 1275 + +D+ E ++ K + L ++ D + +++ E + E+L + + Sbjct: 1166 AVIDKEEMKEFTDIQKYKEELQSVTEELLTKKRDLDQLNSDVQDLRQTIEKEKEEL-EQL 1224 Query: 1276 QSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFX 1335 + E I T+E+V K + + EH+ + +K ++ + + +++IE EK Sbjct: 1225 KKDINREKEDIETLEEVDIQYIKKKAELEHITSEIQKREQILEKQKKNKNQIEQEK---- 1280 Query: 1336 XXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRV 1395 LR E + +++ E + ++ E A +K+ + Sbjct: 1281 KDLQNMKSNLERQLESLRHEKANVEEI-ELKVKDLEMEMADMKRQKQ-----------EI 1328 Query: 1396 NDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEK 1455 D + +LE Q ELK + ++ + + LT+ E E R L+ + ++EDL K Sbjct: 1329 EDTKG-LLEKEKQ-ELKQEK--KELEDQMMDLTREKQETEEERNNLMALKNQLEDLRKIK 1384 Query: 1456 ESELAILRLKM-HENANHYETM----QKESEIERVK---LIEELNV-KITESVSLNKQVA 1506 SEL + ++ HE + + Q++ ++E++K + ++ + K + N++ Sbjct: 1385 -SELVREKTEVDHEQKKLNDDIKMIEQEKEDLEKMKSEIMTQKQEMEKERKEERRNEETR 1443 Query: 1507 ELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQ 1566 L + LE+ N+ L NQ + +EI + VR+ QK ++ D K Sbjct: 1444 RLKEDLEKMSTDVNKQNKDLMNQRDLLEQEREEIKSQLERVRSEIDHEQKKLN--DDKKM 1501 Query: 1567 GRDEQLD-NTMNKELL 1581 E+ D M E++ Sbjct: 1502 IEQEKEDLEKMKSEIM 1517 Score = 143 bits (347), Expect = 3e-32 Identities = 245/1387 (17%), Positives = 580/1387 (41%), Gaps = 80/1387 (5%) Query: 145 THLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXX 204 T L E + Q + + +E D E +N + + ++ KNK Sbjct: 645 TELEREADEIEKIKLETQHERQRVEEMTADFMETMNNERKQLD-KNKVMIEEQKQEMREN 703 Query: 205 XXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAAR 264 + +++ +K++E+ + + + + +KQ+ +D ES + + E + ++ + Sbjct: 704 ISKQIEDIENEKEKSKLREDELK-KLQTEVQKQQK-RDSESLKLDKEAFENEKEAMKQMK 761 Query: 265 FEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTEL 324 ++ ++ ++ + + + K+ E + + +EK I TE+ Sbjct: 762 TDLQIQADEIEKIKLETHHERQRVEEKTAQIQKEREEINTLVEENQQEKNKKTI---TEM 818 Query: 325 TKKIELLEHLNCQIRQTNKEL----ENKLATMGTESKAVSSPSKKGSPLISRKSGRNTAS 380 K+ E LE + I EL E+ L + ++ + L R+S + Sbjct: 819 QKERETLEEMRANISNRESELAKLQEDILQQQQEMDELKNTIMMEMCQLDQRQSDIDLLQ 878 Query: 381 KMKSPWSQLSSETLN----QDTDKKIN--KNEIAKLEMVIQSLNKDLVDKEYVISEKDTX 434 + +L L QD ++ K E+ I+ ++++ ++ +E+ + Sbjct: 879 NKLNLHKELEELNLQKQGIQDERAQLERMKGELQMKADDIERKMQEILYEKQKYAERKSE 938 Query: 435 XXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIK 494 + + +L E +++ E + + + + K +E ++++ ++I+ Sbjct: 939 NYKIQTYLDEANAEVQKLNKELERYDENLEKCKLELDKDIRRNLFKKEEAIEKDKAEKIE 998 Query: 495 DVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSN 554 + +++ ++ K + +L D++ + MI++K + +K +DN K+ N Sbjct: 999 --SEREIQQEKKKLQRSEEELEDKMQKIKREMIELKLLQD-ETDGKRKDVDN--KMRQQN 1053 Query: 555 KEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIES-DVYKKMIEMENLAETRL 613 EI + +++ S K+ L E+ +L+ + D + + I + D K + E E L + Sbjct: 1054 DEIQKEKQQIE--SSKML-LSRERNDLEQNRADLERQKQIMALDKQKLLAENELLEREKA 1110 Query: 614 KAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSA 673 I ++E+ + L +E + K ++ QL+ D++ E + V + ++ Sbjct: 1111 DVIKIIENLE-SLREEATRERATETAQATKREELEQLK-DEINREKEDVEIRRELVEAVI 1168 Query: 674 SKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKIS 733 K+E+ + K KE+L ++L K D+ ++L + +Q DL +EK E++ Sbjct: 1169 DKEEMKEFTDIQKY-KEELQSVTEELLTKKRDL-DQLNSDVQ---DLRQTIEK-EKEELE 1222 Query: 734 ELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRY 793 +L IN E++ I+T +D + ++ +E+I SE+ K + + + +++ +E + Sbjct: 1223 QLKKDINREKED-IETLEEVDIQYIKKKAELEHITSEIQKREQILEKQKKNKNQIEQEKK 1281 Query: 794 SLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQK 853 L+ L L+ + + + ++E EL + + D +KQ EIE L+K Sbjct: 1282 DLQNMKSNLERQLESLR--HEKANVEEIELKVKDLEMEMADMKRQKQ--EIEDTKGLLEK 1337 Query: 854 KNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHE 913 + Q L +E + L+ + D+ + E+ N +++ + +L + HE Sbjct: 1338 EKQELKQEKKELEDQMMDLTREKQETEEERNNLMALKNQLEDLRKIKSELVREKTEVDHE 1397 Query: 914 HQTL------IVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEY 967 + L I Q+K+++E ++ E TQ + +++K E+ E +L+ L++ Sbjct: 1398 QKKLNDDIKMIEQEKEDLEKMKSEIMTQKQEMEKERKE-----ERRNEETRRLKEDLEKM 1452 Query: 968 KNNIENLN---MNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEE 1024 ++ N MN +L + E I +++ +++ D+ ++ +N+ K+ ++Q+ E+ Sbjct: 1453 STDVNKQNKDLMNQRDLLEQEREEIKSQLERVRSEI-DHEQKKLNDDKKM---IEQEKED 1508 Query: 1025 IIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQIL 1084 + + +I + S+ ++K+ Q + ++E + V K +++ ++ +++++ Sbjct: 1509 LEKMKSEIMKQRQQMEEERSELDNKIKQTDLERHDIENSKEIVQKLMVEVEEQRKDIRLQ 1568 Query: 1085 VREQDDQIKELKETKLTFEMNIPK--TEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXL 1142 E D + +++ + + N K E I E + + + + Sbjct: 1569 KEELDIERQKIADEQGLVVQNKAKLQNENERIKEMDEEIKKEKETLKEMEAHLRKEKEEM 1628 Query: 1143 KVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTE-LTGHDVVNQEQINQLKS 1201 + EE +++ L++ S +N + Q+ + L+ E + D +Q + + Sbjct: 1629 RSVIEETQRRQKEDLEKMSTDVNKQNQDLMNQRDLLKQEREERIDEFDAQVSKQKEEDLT 1688 Query: 1202 KLEQLNTENDNLLSTVAELRSSISSAVDQRGF-----EIAELWKQHLAQREADFQKTEHE 1256 K +++ E ++L +E+ ++R E+ + ++ L + EA +K + E Sbjct: 1689 KQKKMEEEKEDLEKMKSEIMKQRQQMEEERSELENKNEVIKKERETLKEMEAYLEKEKEE 1748 Query: 1257 LRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADV 1316 ++ S E Q D + ST K Q L+ + ++ + LQ++ + Sbjct: 1749 MK---SITEETRRQKEDLEKMSTHINEQKQDLRSQRDLLEQEREEINHKWKQLQQRIDEF 1805 Query: 1317 INQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQ---SILNINEE 1373 QI+ + E ++E + + EN+ K+M E+ + E Sbjct: 1806 DAQIKS-QLERKEELDIERQKIADEQDLLIQNKIEQQNENERIKEMDEEIKKERETLKEM 1864 Query: 1374 NAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLE--LKDSEIYQKTHEYTITLTQRN 1431 L+K R D E ++ Q + + ++ ++ E + N Sbjct: 1865 EVNLQKEKEEIESVIEETQRRKEDLEKMSTDINEQKQDLMNQRDLLKQERE------EMN 1918 Query: 1432 DEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIE-E 1490 + ++Q++ E+E L K E + K+ + YE++ +E+ +R +L E E Sbjct: 1919 HKLTQLQQRIDEFETTSNILVTTKMEEKTEMDEKLQQAIKEYESIIEETNRKRTELEEIE 1978 Query: 1491 LNVKITE 1497 K TE Sbjct: 1979 KERKDTE 1985 Score = 138 bits (334), Expect = 1e-30 Identities = 216/1172 (18%), Positives = 499/1172 (42%), Gaps = 93/1172 (7%) Query: 473 EDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSN 532 ED++E AK + Q+ E+ + + D++ + + +E ++ + + K++ Sbjct: 112 EDLSEDAKRKNQVLDEMK-VANESTLADILRERSNLQEMRENISKQTEDVENKKEKIRLR 170 Query: 533 HKLKLKQMQKTI-----DNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVD 587 + KLKQ+Q I + + S+ +E + +++ L K+ L+ + +L+L Sbjct: 171 EE-KLKQLQAEIHKQQSETEKEKSNIERERAAIIKDVEDLQSKIISLDRDAESLKLDREA 229 Query: 588 YDSGR----MIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDK 643 +++ + +++++ ++ M N + K ++ QK ++ +E H + Q + DK Sbjct: 230 FENEKEELKQMKTELEREAETMNNERKQLNKNKEEMQEQKQEMEKERHDMDQSRKSL-DK 288 Query: 644 LADISQLQSDQVCSEIKSV--HLEEQI---DALSASKKELALVIENLKLDKEQLYGTIKD 698 + +LQ + S++ +LE+Q D L + E+ ++ +K + Sbjct: 289 NLKMMKLQKQKTRSKLLRAKENLEKQRLREDELRQLQAEIHKQQREIEKEKINIESERAA 348 Query: 699 LENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQ 758 + D ED+ +K+ ++ L KL++ + +L + N + + KI++ D + Sbjct: 349 IIKDVEDLQHKIICLDRDAESL--KLDREETNRKDMVLNEKNRDIEEKIKS-IQSDKDML 405 Query: 759 ERDLY-IENIESELSKYKSRICRLEES-IAVMEDRRYSLERKADQLGSYLQEKQKAYSEY 816 E++ + +E SEL K K + + +E+ +A ++ R LE+ + + + E + + Sbjct: 406 EKEKHDLEKTRSELYKVKEDLEKQKENTLAEIQKEREDLEKMNENITREMHEIKHQEEQM 465 Query: 817 TIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHY 876 ++DEL + + + +EK+ I + +L + L ++ N+ + M+ Sbjct: 466 NQKQDELDQLKTEIQNLQQELEKEKEIIMKDRSQLDLRQSELDKQQTNMNDIMETMKNER 525 Query: 877 NALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFN--- 933 L + + + E K + +L + +I E Q K EIE +++E Sbjct: 526 KQLDKDKEEMEEQKQEMEKMKIELEREADEISKIKEE-----TQNKNEIEKIKLETQHDR 580 Query: 934 ---TQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELID 990 ++ + I+ K+V E+ K + +LE + E + E + L KM EL Sbjct: 581 QRVEEMAAQIQKKQVFEEEKNKLEQMKIELEREADEIRKIKEETQNERQSLEKMTEEL-- 638 Query: 991 KHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKL 1050 +K +T+ E+ +EI K+ L+ + E Q++ +M +++ +L Sbjct: 639 -KKEKMKTE----LEREADEIEKIK--LETQHE-----RQRVEEMTADFMETMNNERKQL 686 Query: 1051 AQFTTKLENMEEEM-QRVSKQLLD-------SKQHNEELQILVRE-QDDQIKELKETKLT 1101 + +E ++EM + +SKQ+ D SK +EL+ L E Q Q ++ + KL Sbjct: 687 DKNKVMIEEQKQEMRENISKQIEDIENEKEKSKLREDELKKLQTEVQKQQKRDSESLKLD 746 Query: 1102 FEMNIPKTEGM-IISSTIEPMSDDANNV--DXXXXXXXXXXXXLKVQEEEEFIQE--RSV 1156 E + E M + + ++ +D+ + + ++Q+E E I Sbjct: 747 KEAFENEKEAMKQMKTDLQIQADEIEKIKLETHHERQRVEEKTAQIQKEREEINTLVEEN 806 Query: 1157 LQEQSAKLNTELQ-------ECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTE 1209 QE++ K TE+Q E I E+ +L + Q+++++LK+ + + Sbjct: 807 QQEKNKKTITEMQKERETLEEMRANISNRESELAKLQEDILQQQQEMDELKNTIMMEMCQ 866 Query: 1210 NDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYE 1269 D S + L++ ++ + E L KQ + A ++ + EL+++ E K + Sbjct: 867 LDQRQSDIDLLQNKLNL---HKELEELNLQKQGIQDERAQLERMKGELQMKADDIERKMQ 923 Query: 1270 QLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIED 1329 ++L Q + ++ +Q L + ++ L ++ +E + E++ Sbjct: 924 EILYEKQKYAERKSENY-------KIQTYLDEANAEVQKLNKELERYDENLEKCKLELDK 976 Query: 1330 EKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXX 1389 + + E Q K+ ++S + ++ ++K+ Sbjct: 977 DIRRNLFKKEEAIEKDKAEKIESEREIQQEKKKLQRSEEELEDKMQKIKREMIELKLLQD 1036 Query: 1390 XXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFEN-----VRQQLVEY 1444 + D + K+ + +++ + +I + +RND +N ++Q++ Sbjct: 1037 ETDGKRKDVDNKMRQQNDEIQKEKQQIESSK---MLLSRERNDLEQNRADLERQKQIMAL 1093 Query: 1445 EKR---IEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSL 1501 +K+ E+ E+E I ++ E+ T ++ +E + EEL ++ + ++ Sbjct: 1094 DKQKLLAENELLEREKADVIKIIENLESLREEATRERATETAQATKREELE-QLKDEINR 1152 Query: 1502 NKQVAELNKALEEEVAKTNEMQ--TALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVS 1559 K+ E+ + L E V EM+ T ++ + E+ ++ +E+ + + +S +Q + Sbjct: 1153 EKEDVEIRRELVEAVIDKEEMKEFTDIQKYKEELQSVTEELLTKKRDLDQLNSDVQ-DLR 1211 Query: 1560 FASDTKQGRDEQLDNTMNKELLDAVPRAELDL 1591 + ++ EQL +N+E D E+D+ Sbjct: 1212 QTIEKEKEELEQLKKDINREKEDIETLEEVDI 1243 Score = 117 bits (282), Expect = 2e-24 Identities = 197/908 (21%), Positives = 414/908 (45%), Gaps = 92/908 (10%) Query: 213 DTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEAN--KLLEAARFE-ISL 269 D Q + +Q+ +E E K+E ++L KDI + I +LEE + + + A E I+ Sbjct: 1199 DLDQLNSDVQDLRQTIEKE-KEELEQLKKDINREKEDIETLEEVDIQYIKKKAELEHITS 1257 Query: 270 EHSKLAQELEQXXXXXXXXXXXXXXLA--KQSIEPSCE----EKTEIEEKG------SLE 317 E K Q LE+ L K ++E E EK +EE +E Sbjct: 1258 EIQKREQILEKQKKNKNQIEQEKKDLQNMKSNLERQLESLRHEKANVEEIELKVKDLEME 1317 Query: 318 IANMTELTKKIE----LLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRK 373 +A+M ++IE LLE +++Q KELE+++ + E + ++ + L++ K Sbjct: 1318 MADMKRQKQEIEDTKGLLEKEKQELKQEKKELEDQMMDLTREKQETE---EERNNLMALK 1374 Query: 374 SGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDT 433 + K+KS +L E D ++K ++I +E + L K K ++++K Sbjct: 1375 NQLEDLRKIKS---ELVREKTEVDHEQKKLNDDIKMIEQEKEDLEKM---KSEIMTQKQE 1428 Query: 434 XXXXXXXXXXGKDTLIAQLQLEHQQ---HMEGPSLIHVGTNTEDVNEIAKVQ-EQLKQEL 489 ++T + LE + + L++ E E K Q E+++ E+ Sbjct: 1429 MEKERKEERRNEETRRLKEDLEKMSTDVNKQNKDLMNQRDLLEQEREEIKSQLERVRSEI 1488 Query: 490 NDEIKDVNV-KDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQM---QKTID 545 + E K +N K +IE+ K E + ++ EI + M + +S K+KQ + I+ Sbjct: 1489 DHEQKKLNDDKKMIEQEK---EDLEKMKSEIMKQRQQMEEERSELDNKIKQTDLERHDIE 1545 Query: 546 NFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNL--QLHLVDYDSGRMI-ESDVYKKM 602 N ++ K +V + E+ + + EL+ E+ + + LV + ++ E++ K+M Sbjct: 1546 NSKEIVQ--KLMVEVEEQRKDIRLQKEELDIERQKIADEQGLVVQNKAKLQNENERIKEM 1603 Query: 603 IEMENLAETRLKAISL-LESQKFDLVQELHILQQKYDEVEDKLA-DISQLQSDQVCS-EI 659 E + LK + L +K ++ + Q++ E +K++ D+++ D + ++ Sbjct: 1604 DEEIKKEKETLKEMEAHLRKEKEEMRSVIEETQRRQKEDLEKMSTDVNKQNQDLMNQRDL 1663 Query: 660 KSVHLEEQIDALSA--SKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQEN 717 EE+ID A SK++ + + K+++E+ +DLE K +IM + Q +E Sbjct: 1664 LKQEREERIDEFDAQVSKQKEEDLTKQKKMEEEK-----EDLEKMKSEIMKQRQQMEEER 1718 Query: 718 MDLTDKLE--KMSAEKISELLAKINHE-EQSKIQTQFGIDAKIQERDLYIENIESELSKY 774 +L +K E K E + E+ A + E E+ K T+ + + Q+ DL E + + +++ Sbjct: 1719 SELENKNEVIKKERETLKEMEAYLEKEKEEMKSITE---ETRRQKEDL--EKMSTHINEQ 1773 Query: 775 KSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDEL-VNRLAVLMDH 833 K + R + + +E R + K QL + E +++EL + R + + Sbjct: 1774 KQDL-RSQRDL--LEQEREEINHKWKQLQQRIDEFDAQIKSQLERKEELDIERQKIADEQ 1830 Query: 834 DRVVEKQLLEIEHENKELQKKNQILLEENQNL---QISLSDMQQHYNALVEKA-NRTDLA 889 D +++ ++ E ++EN+ +++ ++ + +E + L +++L ++ +++E+ R + Sbjct: 1831 DLLIQNKI-EQQNENERIKEMDEEIKKERETLKEMEVNLQKEKEEIESVIEETQRRKEDL 1889 Query: 890 ESESTKYQTQLRDLESN---LKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVL 946 E ST Q +DL + LK+ E + Q ++ I++ E N + + + +K + Sbjct: 1890 EKMSTDINEQKQDLMNQRDLLKQEREEMNHKLTQLQQRIDEFETTSNILVTTKMEEKTEM 1949 Query: 947 NEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQ 1006 +EK L+ ++EY++ IE N EL ++ E D ++ ++ T + Sbjct: 1950 DEK----------LQQAIKEYESIIEETNRKRTELEEIEKERKDTEKERGCSRGGTETGK 1999 Query: 1007 YINE-----INKLNALLKQ--KDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLEN 1059 E I+++ +L + K+++ + N++I Q + + ++ + L+N Sbjct: 2000 KGGEFERIQIDEVKRILSEIHKEKKELERNKQILEHQREALLEIKKEREEIEKMKADLQN 2059 Query: 1060 MEEEMQRV 1067 E + + Sbjct: 2060 KLREAENM 2067 Score = 104 bits (249), Expect = 2e-20 Identities = 168/907 (18%), Positives = 390/907 (42%), Gaps = 80/907 (8%) Query: 731 KISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMED 790 +I L ++ E++ ++ + +D + E D N+ + K L+E + +M+ Sbjct: 4 EIQNLQQELEKEKEIIMKARSQLDLRQSELDKQQTNMNDIMETMKKS---LDEDLKMMKL 60 Query: 791 RRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKE 850 ++ +E + +L E ++ E ++E N + +++ E E E +++ Sbjct: 61 QKQVIEEEKSKLKQMKIELEREADEIRKVKEETQNERQIF---EKMTEALKKEREDLSED 117 Query: 851 LQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRI 910 ++KNQ+L E + +L+D+ + + L E + + ++R E LK++ Sbjct: 118 AKRKNQVLDEMKVANESTLADILRERSNLQEMRENISKQTEDVENKKEKIRLREEKLKQL 177 Query: 911 ---THEHQTLIVQKK-----------KEIEDLE---IEFNTQIESAIRDKKVLNEKYEKN 953 H+ Q+ ++K K++EDL+ I + ES D++ + E+ Sbjct: 178 QAEIHKQQSETEKEKSNIERERAAIIKDVEDLQSKIISLDRDAESLKLDREAFENEKEEL 237 Query: 954 IEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLEL-IDKHVQKQQTQSPDYTEQY--INE 1010 + T+LE + + N + LN N EE+ + E+ ++H Q +S D + + + Sbjct: 238 KQMKTELEREAETMNNERKQLNKNKEEMQEQKQEMEKERHDMDQSRKSLDKNLKMMKLQK 297 Query: 1011 INKLNALLKQK---------DEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENME 1061 + LL+ K ++E+ L +I+ Q + ES+ A +E+++ Sbjct: 298 QKTRSKLLRAKENLEKQRLREDELRQLQAEIHKQQREIEKEKINIESERAAIIKDVEDLQ 357 Query: 1062 EE---MQRVSKQL-LDSKQHNEELQIL---VREQDDQIKELKETKLTFEMNIPKTEGMII 1114 + + R ++ L LD ++ N + +L R+ +++IK ++ K E K + Sbjct: 358 HKIICLDRDAESLKLDREETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKE--KHDLEKT 415 Query: 1115 SSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTK 1174 S + + +D + E +E ++ Q ++N + E Sbjct: 416 RSELYKVKEDLEKQKENTLAEIQKEREDLEKMNENITREMHEIKHQEEQMNQKQDELDQL 475 Query: 1175 IIQLETLNTELTGHDVV---NQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQR 1231 +++ L EL + ++ Q++ +S+L++ T ++++ T+ R + ++ Sbjct: 476 KTEIQNLQQELEKEKEIIMKDRSQLDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEM 535 Query: 1232 GFEIAELWKQHL-AQREAD-----FQKTEHELRVQLSAFESKYE-QLLDSVQSSTQEETN 1284 + E+ K + +READ ++T+++ ++ E++++ Q ++ + + Q++ Sbjct: 536 EEQKQEMEKMKIELEREADEISKIKEETQNKNEIEKIKLETQHDRQRVEEMAAQIQKKQV 595 Query: 1285 KIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXX 1344 ++ ++ +L+ + + +R ++E+ + +E + E++ EK+ Sbjct: 596 FEEEKNKLEQMKIELEREADEIRKIKEETQNERQSLEKMTEELKKEKM--KTELEREADE 653 Query: 1345 XXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKS----SXXXXXXXXXXXXRVNDAE- 1399 + + E Q ++M + +N E QL K+ ++ D E Sbjct: 654 IEKIKLETQHERQRVEEMTADFMETMNNERKQLDKNKVMIEEQKQEMRENISKQIEDIEN 713 Query: 1400 AKVLELTHQLELK--DSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKES 1457 K + ELK +E+ ++ + +L + FEN ++ + + + DL + + Sbjct: 714 EKEKSKLREDELKKLQTEVQKQQKRDSESLKLDKEAFENEKEAMKQMK---TDLQIQAD- 769 Query: 1458 ELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITES--VSLNKQVAELNKALEEE 1515 E+ ++L+ H E +K ++I++ + EE+N + E+ K + E+ K E E Sbjct: 770 EIEKIKLETHHERQRVE--EKTAQIQKER--EEINTLVEENQQEKNKKTITEMQK--ERE 823 Query: 1516 VAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNT 1575 + EM+ + N+E E+ L ++I Q + + I + D +Q + L N Sbjct: 824 TLE--EMRANISNRESELAKLQEDILQQQQEMDELKNTIMMEMC-QLDQRQSDIDLLQNK 880 Query: 1576 MN--KEL 1580 +N KEL Sbjct: 881 LNLHKEL 887 Score = 97.5 bits (232), Expect = 3e-18 Identities = 140/772 (18%), Positives = 331/772 (42%), Gaps = 75/772 (9%) Query: 858 LLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHE---- 913 L E QNLQ ++++ +++ ++ DL +SE K QT + D+ +K+ E Sbjct: 1 LKTEIQNLQ---QELEKEKEIIMKARSQLDLRQSELDKQQTNMNDIMETMKKSLDEDLKM 57 Query: 914 ---HQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQ-LEAQLQEYKN 969 + +I ++K +++ ++IE + + IR K + + E +T+ L+ + ++ Sbjct: 58 MKLQKQVIEEEKSKLKQMKIELEREADE-IRKVKEETQNERQIFEKMTEALKKEREDLSE 116 Query: 970 NIENLNMNVEEL-------------NKMNLELIDKHVQKQQTQSPDYTEQYI----NEIN 1012 + + N ++E+ + NL+ + +++ K QT+ + ++ I ++ Sbjct: 117 DAKRKNQVLDEMKVANESTLADILRERSNLQEMRENISK-QTEDVENKKEKIRLREEKLK 175 Query: 1013 KLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLL 1072 +L A + ++ E I + + + V D +SK+ E+++ + + + Sbjct: 176 QLQAEIHKQQSETEKEKSNIERERAAIIKDVEDLQSKIISLDRDAESLKLDREAFENEKE 235 Query: 1073 DSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVD--X 1130 + KQ EL+ +++ K+L + K EM K E + M ++D Sbjct: 236 ELKQMKTELEREAETMNNERKQLNKNK--EEMQEQKQE---MEKERHDMDQSRKSLDKNL 290 Query: 1131 XXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDV 1190 K+ +E ++++ + +++ +L E+ + + I+ E +N E + Sbjct: 291 KMMKLQKQKTRSKLLRAKENLEKQRLREDELRQLQAEIHK-QQREIEKEKINIESERAAI 349 Query: 1191 VNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELW------KQHLA 1244 + + + L+ K+ L+ + ++L E ++++ +I E K L Sbjct: 350 I--KDVEDLQHKIICLDRDAESLKLDREETNRK-DMVLNEKNRDIEEKIKSIQSDKDMLE 406 Query: 1245 QREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQ--EETNKIVTM---------EQVT 1293 + + D +KT EL E + E L +Q + E+ N+ +T EQ+ Sbjct: 407 KEKHDLEKTRSELYKVKEDLEKQKENTLAEIQKEREDLEKMNENITREMHEIKHQEEQMN 466 Query: 1294 SLQNKLQDKEEHLRNLQ---EKYADVI----NQIEILRSEIEDEKVAFXXXXXXXXXXXX 1346 Q++L + ++NLQ EK ++I +Q+++ +SE++ ++ Sbjct: 467 QKQDELDQLKTEIQNLQQELEKEKEIIMKDRSQLDLRQSELDKQQTNMNDIMETMKNERK 526 Query: 1347 XXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDA--EAKVLE 1404 D + E + KQ E+ + + E ++ K ++ +V E Sbjct: 527 QLDKD-KEEMEEQKQEMEKMKIELEREADEISKIKEETQNKNEIEKIKLETQHDRQRVEE 585 Query: 1405 LTHQLELKD--SEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAIL 1462 + Q++ K E K + I L + DE ++++ + +E +T E + E + Sbjct: 586 MAAQIQKKQVFEEEKNKLEQMKIELEREADEIRKIKEETQNERQSLEKMTEELKKEK--M 643 Query: 1463 RLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEM 1522 + ++ A+ E ++ E++ ER + +EE+ E+++ ++ + NK + EE + EM Sbjct: 644 KTELEREADEIEKIKLETQHERQR-VEEMTADFMETMNNERKQLDKNKVMIEE--QKQEM 700 Query: 1523 QTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDN 1574 + + Q +I ++ ++ ++ +++QK S++ + E +N Sbjct: 701 RENISKQIEDIENEKEKSKLREDELKKLQTEVQKQQKRDSESLKLDKEAFEN 752 Score = 93.5 bits (222), Expect = 4e-17 Identities = 145/753 (19%), Positives = 327/753 (43%), Gaps = 54/753 (7%) Query: 148 SNTIKEKDNALSVLQVKMKIM-ETTILDL-QEKINEKDQIIEA-KNKATTXXXXXXXXXX 204 +N + K+ + ++K +++ E T +D Q+K+N+ ++IE K Sbjct: 1368 NNLMALKNQLEDLRKIKSELVREKTEVDHEQKKLNDDIKMIEQEKEDLEKMKSEIMTQKQ 1427 Query: 205 XXXXXXXEDTKQQMTK-MQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAA 263 E+ + + T+ ++E+ M + + + L+ +D+ EE LE Sbjct: 1428 EMEKERKEERRNEETRRLKEDLEKMSTDVNKQNKDLMNQ---RDLLEQEREEIKSQLERV 1484 Query: 264 RFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTE 323 R EI E KL + + + KQ + EE++E++ K + Sbjct: 1485 RSEIDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQRQQME-EERSELDNKIKQTDLERHD 1543 Query: 324 LTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMK 383 + E+++ L ++ + K++ + + E + ++ ++G + ++ +N ++K Sbjct: 1544 IENSKEIVQKLMVEVEEQRKDIRLQKEELDIERQKIAD--EQGLVVQNKAKLQNENERIK 1601 Query: 384 SPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXX 443 + D++I K + EM L K+ + VI E Sbjct: 1602 -------------EMDEEIKKEKETLKEMEAH-LRKEKEEMRSVIEETQRRQKEDL---- 1643 Query: 444 GKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEI-AKVQEQLKQELNDEIKDVNVKDLI 502 + + + ++Q M L+ E ++E A+V +Q +++L + K K+ + Sbjct: 1644 --EKMSTDVNKQNQDLMNQRDLLKQ-EREERIDEFDAQVSKQKEEDLTKQKKMEEEKEDL 1700 Query: 503 EKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDS-NKEIVRLT 561 EK+KS + Q +E + +N +V + LK+M+ ++ + S +E R Sbjct: 1701 EKMKSEIMKQRQQMEEERSELENKNEVIKKERETLKEMEAYLEKEKEEMKSITEETRRQK 1760 Query: 562 EELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIES--DVYKKMIEMENLAETRLKAISLL 619 E+L +S + E +++ + Q L++ + + + +++ E + +++L+ L Sbjct: 1761 EDLEKMSTHINEQKQDLRS-QRDLLEQEREEINHKWKQLQQRIDEFDAQIKSQLERKEEL 1819 Query: 620 ESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELA 679 + ++ + E +L Q E +++ I ++ +++ E ++ L+E L K+E+ Sbjct: 1820 DIERQKIADEQDLLIQNKIEQQNENERIKEMD-EEIKKERET--LKEMEVNLQKEKEEIE 1876 Query: 680 LVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKI 739 VIE + KE L D+ K+D+MN+ QE ++ KL ++ ++I E Sbjct: 1877 SVIEETQRRKEDLEKMSTDINEQKQDLMNQRDLLKQEREEMNHKLTQLQ-QRIDEFETTS 1935 Query: 740 NHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKA 799 N +K++ + +D K+Q+ E+I E ++ ++ + +E+ E + ER Sbjct: 1936 NILVTTKMEEKTEMDEKLQQAIKEYESIIEETNRKRTELEEIEK-----ERKDTEKERGC 1990 Query: 800 DQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILL 859 + G+ +K + IQ DE+ L+ + + +E+ +EH+ + L + + Sbjct: 1991 SRGGTETGKKGGEFER--IQIDEVKRILSEIHKEKKELERNKQILEHQREALLE----IK 2044 Query: 860 EENQNLQISLSDMQQHYNALVEKANRTDLAESE 892 +E + ++ +D+Q N L E N D+ + E Sbjct: 2045 KEREEIEKMKADLQ---NKLREAENMRDIMKRE 2074 Score = 44.4 bits (100), Expect = 0.026 Identities = 57/320 (17%), Positives = 126/320 (39%), Gaps = 15/320 (4%) Query: 1295 LQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRT 1354 L+ ++Q+ ++ L +E +Q+++ +SE++ ++ ++ Sbjct: 1 LKTEIQNLQQELEKEKEIIMKARSQLDLRQSELDKQQTNMNDIMETMKKSLDEDLKMMKL 60 Query: 1355 ENQ---SYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLEL 1411 + Q K +Q + + E +++K + + +L+ + Sbjct: 61 QKQVIEEEKSKLKQMKIELEREADEIRKVKEETQNERQIFEKMTEALKKEREDLSEDAKR 120 Query: 1412 KDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKES------ELAILRLK 1465 K+ + + TL E N+++ K+ ED+ +KE +L L+ + Sbjct: 121 KNQVLDEMKVANESTLADILRERSNLQEMRENISKQTEDVENKKEKIRLREEKLKQLQAE 180 Query: 1466 MHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAEL---NKALEEEVAKTNEM 1522 +H+ + E + E ER +I+++ ++ +SL++ L +A E E + +M Sbjct: 181 IHKQQSETEKEKSNIERERAAIIKDVEDLQSKIISLDRDAESLKLDREAFENEKEELKQM 240 Query: 1523 QTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLD 1582 +T LE E T+N+E L + Q+ D Q R N +L Sbjct: 241 KTELER---EAETMNNERKQLNKNKEEMQEQKQEMEKERHDMDQSRKSLDKNLKMMKLQK 297 Query: 1583 AVPRAELDLAMYMLHQRDVR 1602 R++L A L ++ +R Sbjct: 298 QKTRSKLLRAKENLEKQRLR 317 >UniRef50_UPI00006CB2DA Cluster: Viral A-type inclusion protein repeat containing protein; n=1; Tetrahymena thermophila SB210|Rep: Viral A-type inclusion protein repeat containing protein - Tetrahymena thermophila SB210 Length = 2199 Score = 184 bits (449), Expect = 1e-44 Identities = 293/1474 (19%), Positives = 629/1474 (42%), Gaps = 130/1474 (8%) Query: 158 LSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKA---TTXXXXXXXXXXXXXXXXXEDT 214 + +L+ ++K TI D E I K +IE KNK E+ Sbjct: 524 IKILEEQIKDYVETIKDKNEIIQAKSNLIEEKNKVIQMNDILIAENEELMKSNTDKIEEL 583 Query: 215 KQQMTKMQENFIAMEAEWKDEKQRLLKDIESK-DVRISSLEEANKLLEAARFEISLEHSK 273 +Q+ + + + +E + + K+ K ++ D+ ++ + LE +I + ++ Sbjct: 584 DEQILEKDKKILQLEIDLDNVKKGFEKVLQQNTDMYMNQKSDTLSQLENLTNKIQEQSNE 643 Query: 274 LAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEH 333 L ++L++ L K I + +EK + E + N ++T K +E Sbjct: 644 LDEKLDEIADLNNTI------LDKDKIIRTYKEKIDQYEADLKQ--NKEQITSKTLEIEK 695 Query: 334 LNCQI---RQTNKELENKLATMGTESKAVSSPSKKGSPLISR--KSGRNTASK---MKSP 385 L QI N+ + LA E ++ K + L+ + KS K MK Sbjct: 696 LTEQIGFLELENERFQQVLAHTQVERMSIKHEFDKDTELLQQQLKSAMGEYIKKIEMKDF 755 Query: 386 WSQLSSETLNQDT-DKKINKNEIAKLEMVIQSLNKDL-----VDKEYVISEKDTXXXXXX 439 Q +E +N ++ EI K +I+ LN D+ + K + Sbjct: 756 EIQGQAEQINNLVIQMNTHQEEITKKNQIIEDLNNDISRLSNIQKSQLCQISILNEFCLS 815 Query: 440 XXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVK 499 + + +L ++ + + E++N + E LK+ L E ++ + Sbjct: 816 NNQNEQILKMVPKRLIYRLYKLQANQKFNLIFQEEINTYTQEIETLKENLKKE--ELKSQ 873 Query: 500 DLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVR 559 DL E K+ E+QI Q I ++ + +++ + ++Q D K++ S +E + Sbjct: 874 DLEESKKNQEDQIKQQEQNIKELHEKLKEIEKRQEEINTEIQNLKDEKEKLTQSIEEDKK 933 Query: 560 LTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLL 619 + EE L++ +++ ++E +Q V+ + +K+ E+E + I+ L Sbjct: 934 VIEE---LNKSISQKDDELKEIQQQCVN----------LKQKIEELEKDVSDKTSEINQL 980 Query: 620 ESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELA 679 DL++ H Q+K D+ ED L QS + E L+++I+ + ++ Sbjct: 981 N----DLIKN-H--QEKIDQQEDSL------QSKEKTIEETKEELKKKIEVIEKLHEQFN 1027 Query: 680 LVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKI 739 + L +++ I++ + ++++ K QN I E + ++ E++ I E K+ Sbjct: 1028 ETNQTLGQRAQEIEQIIENKQQKEKELQEK-QNKIDEKQKIIEEKEEI----IKENEQKL 1082 Query: 740 NHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKA 799 + + Q I+ K+ E+ E+E+ + + ++ EE +A ++ + +++ Sbjct: 1083 KQANEQLEENQNAIN-KLSEQQT---QSEAEIKQLQEKLKDTEELLASAKENLQNSQKEL 1138 Query: 800 DQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILL 859 +Q L +KQK Y E E ELV + A + + +EK++ ++ + + L+++++ + Sbjct: 1139 EQSQESLSQKQKLYDE----EHELVQKKAEQITN---LEKEISKLNEDLESLKQEHKSFI 1191 Query: 860 EE-NQNLQISLSDMQQHYNA----LVEKANRTDLAESESTKYQTQLRDLESNLKRITHEH 914 E N++ Q + + Q N + E + D SES++ Q+ D ++++ + Sbjct: 1192 ENTNKSHQEQIDSLNQQINQFKQNISENQKQIDQLNSESSQKSNQISDKNEEIQQLKGKI 1251 Query: 915 QTL---IVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNI 971 +TL + +KK ++L+I+ Q E++ K +L + + + + L ++ + Sbjct: 1252 ETLNEDLNSQKKTADELKIQLTAQQENSKEIKNMLQQTESQRDKLMDNLNSKDSQTAQLN 1311 Query: 972 ENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQK 1031 + L +E N+ ++ I +K + Q EQ EI +N L+Q +++ K Sbjct: 1312 QKLG-TLESQNEQQIKKISSQKEKIK-QLKASLEQNNLEIQSINKQLEQTKQDLQKEQNK 1369 Query: 1032 INNAQVSYMSMVSDYESKLAQFT-TKLEN---MEEEMQRVSKQLLDSKQHNEELQILVRE 1087 N S + +SK+A+ K +N + E Q+ S+ D E+LQ L + Sbjct: 1370 YENTSGQQSSTIEQLKSKIAELEQAKSQNEQTISSEKQKNSQLEKDQNSIKEDLQTLQQT 1429 Query: 1088 QDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEE 1147 ++ ELK L+ E+ K EG I+ +S +N + E+ Sbjct: 1430 LKEKQNELKN--LSSEIEKFKEEGKSSKQQIDELSK--SNEENLSQINSLNIQIQVFSEQ 1485 Query: 1148 EEFIQERSVLQEQS-AKLNTELQ--ECYTKIIQLETL--NTELTGHDVVNQEQINQLKSK 1202 E I ++Q+ +KLN + E K +Q++ + ++ +++I QL S Sbjct: 1486 NETISAELTKKDQTISKLNEQNSQFEIDIKTLQMKIREQSEQMNEEKEFQEKKIQQLNST 1545 Query: 1203 LEQLNTENDNLLSTV-AELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQL 1261 ++QL + + + T+ A+L+ I + + F+ + K L + Q R Q+ Sbjct: 1546 IDQLKLQIKSQVETINAKLKEKIQES--ENAFDELDTTKTELLK----LQDIIDGQRSQI 1599 Query: 1262 SAFESKYEQLLDSVQSSTQEETNKIVTME-QVTSLQNKLQDKEEHLRNLQEKYADVINQI 1320 +++ E+L + + S EE K + ++ + + K++ E ++ LQEK Q Sbjct: 1600 ITLQNELEKL-NQLNSQLLEEKMKAESYHVKIQNQEEKIKSNAEMIQVLQEKLKTSEQQA 1658 Query: 1321 EILRSEI-------EDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEE 1373 +L+ ++ +D++ L + Q + Q + + + IN Sbjct: 1659 NLLKQQLKNKQYQEDDQQRETRKSVSFLTSQAEMNKYQLDNQKQKWDQQEAEYKIKINSL 1718 Query: 1374 NAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQL-ELK---------DSEIYQKTHEY 1423 NAQ+++ + + E+ V++ L +LK + + QK E Sbjct: 1719 NAQIQQLIEEKQSNIDMKKSFMKERESVVVDKEKALRDLKQLYAQSRKNEESLEQKISEM 1778 Query: 1424 TITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIE 1483 + N E E++R QL+ ++IE + Y ++ E + + +AN + +Q+ES + Sbjct: 1779 EKVILNMNQEIESLRTQLIRANQQIEQMAYARKYEAS--QYADLRSANLSKALQQES-LP 1835 Query: 1484 RVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTA-LENQEIEIVTLNDEITN 1542 + I++ + E LN ++++N + ++ A+ + + A L N+ + ++ D+ N Sbjct: 1836 TLNNIQKQGSNMGE---LN--LSQINHSFTQKDAEDDNIMLADLANEILSLIQQGDQQNN 1890 Query: 1543 LQNMVRASS--SKIQKHVSFASDTKQGRDEQLDN 1574 N+ +++S +I F + T + ++ L + Sbjct: 1891 EANLKQSASVGGEIANSSQFVTFTPEDENQILSS 1924 Score = 182 bits (442), Expect = 1e-43 Identities = 306/1488 (20%), Positives = 619/1488 (41%), Gaps = 137/1488 (9%) Query: 174 DLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWK 233 DL K+ + ++ +E+KN T E+T Q+ ++Q + A + Sbjct: 270 DLTTKLQDLNKELESKNNEYTQNLEQKEKEIQLQQKQAEETTSQL-QLQIQTLKQSANQE 328 Query: 234 -----DEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXX 288 ++ + L +I ++++ L E N L++ +I+ +H K E+E Sbjct: 329 NLNLNEQFEEKLNNIREQELQKFKLAEENHLIQIE--QITTKHKKEISEIESS------- 379 Query: 289 XXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENK 348 + K +++ S + +IEE L I ++ + + I+ +E + + ++ K + K Sbjct: 380 ------IKKLTLD-SNKRYQQIEEVHLLSIESLKQ--QHIKTIEAMKAEQQENEKSIRQK 430 Query: 349 ----LATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINK 404 L + E KA+ ++K L S + N S ++ L Q+ + K K Sbjct: 431 YEKHLDRLQDEIKAIQEANQK---LNSEQE--NKISNLEGQIKDLEKSKNKQNEEIKQLK 485 Query: 405 NEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPS 464 N++ + ++ +V E +S +D+ K L Q++ + + Sbjct: 486 NKLNEKNEKFDIMSTSIVSTES-LSVRDSDLKTTEYIKKIK-ILEEQIKDYVETIKDKNE 543 Query: 465 LIHVGTNT-EDVNEIAKVQEQLKQELNDEIKDVN---VKDLIEKLKSAEEQITQLNDEID 520 +I +N E+ N++ ++ + L E N+E+ N +++L E++ +++I QL ++D Sbjct: 544 IIQAKSNLIEEKNKVIQMNDILIAE-NEELMKSNTDKIEELDEQILEKDKKILQLEIDLD 602 Query: 521 AANKNMIKV-KSNHKLKLKQMQKTIDNF----SKVSDSNKEIVRLTEELHHLSQKVAELE 575 K KV + N + + Q T+ +K+ + + E+ +E+ L+ + + + Sbjct: 603 NVKKGFEKVLQQNTDMYMNQKSDTLSQLENLTNKIQEQSNELDEKLDEIADLNNTILDKD 662 Query: 576 EEKGNLQLHLVDYDSG-RMIESDVYKKMIEMENLAETRLKAISLLESQKFDLV-QELHIL 633 + + + Y++ + + + K +E+E L E ++ + L E+++F V + Sbjct: 663 KIIRTYKEKIDQYEADLKQNKEQITSKTLEIEKLTE-QIGFLEL-ENERFQQVLAHTQVE 720 Query: 634 QQKYDEVEDKLADISQLQSDQVCSE-IKSVHLEE-QIDALSASKKELALVIENLKLDKEQ 691 + DK ++ Q Q E IK + +++ +I + L + + + + + Sbjct: 721 RMSIKHEFDKDTELLQQQLKSAMGEYIKKIEMKDFEIQGQAEQINNLVIQMNTHQEEITK 780 Query: 692 LYGTIKDLENDKEDIMNKLQNYIQENMDLTDK-LEKMSAEKISELLAKINHEEQSKIQTQ 750 I+DL ND + N ++ + + L + L E+I +++ K K+Q Sbjct: 781 KNQIIEDLNNDISRLSNIQKSQLCQISILNEFCLSNNQNEQILKMVPKRLIYRLYKLQAN 840 Query: 751 FGIDAKIQER-DLY---IENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYL 806 + QE + Y IE ++ L K + + LEES ED+ E+ +L L Sbjct: 841 QKFNLIFQEEINTYTQEIETLKENLKKEELKSQDLEESKKNQEDQIKQQEQNIKELHEKL 900 Query: 807 QEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQ--- 863 +E +K E + L + L +E+ IE NK + +K+ L E Q Sbjct: 901 KEIEKRQEEINTEIQNLKDEKEKLTQS---IEEDKKVIEELNKSISQKDDELKEIQQQCV 957 Query: 864 NLQISLSDMQQHYNALVEKANR-TDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKK 922 NL+ + ++++ + + N+ DL ++ K Q L+S K I + L K Sbjct: 958 NLKQKIEELEKDVSDKTSEINQLNDLIKNHQEKIDQQEDSLQSKEKTIEETKEEL----K 1013 Query: 923 KEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEEL- 981 K+IE +E + + Q + ++ E+ IE Q E +LQE +N I+ +EE Sbjct: 1014 KKIEVIE-KLHEQFNETNQTLGQRAQEIEQIIENKQQKEKELQEKQNKIDEKQKIIEEKE 1072 Query: 982 -----NKMNLELIDKHVQKQQTQSPDYTEQYIN---EINKLNALLKQKDEEIIALNQKIN 1033 N+ L+ ++ +++ Q +EQ EI +L LK +E + + + + Sbjct: 1073 EIIKENEQKLKQANEQLEENQNAINKLSEQQTQSEAEIKQLQEKLKDTEELLASAKENLQ 1132 Query: 1034 NAQ---------VSYMSMVSDYESKLAQFTTK-LENMEEEMQRVSKQLLDSKQ-HNEELQ 1082 N+Q +S + D E +L Q + + N+E+E+ ++++ L KQ H ++ Sbjct: 1133 NSQKELEQSQESLSQKQKLYDEEHELVQKKAEQITNLEKEISKLNEDLESLKQEHKSFIE 1192 Query: 1083 ILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXL 1142 + +QI L + F+ NI + + I E S +N + + Sbjct: 1193 NTNKSHQEQIDSLNQQINQFKQNISENQKQIDQLNSES-SQKSNQISDKNEEIQQLKGKI 1251 Query: 1143 KVQEEEEFIQERSV--LQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLK 1200 + E+ Q+++ L+ Q +E + Q E+ +L + Q QL Sbjct: 1252 ETLNEDLNSQKKTADELKIQLTAQQENSKEIKNMLQQTESQRDKLMDNLNSKDSQTAQLN 1311 Query: 1201 SKLEQLNTENDNLLSTVAELRSSIS---SAVDQRGFEIAELWKQHLAQREADFQKTEHEL 1257 KL L ++N+ + ++ + I ++++Q EI + KQ L Q + D QK +++ Sbjct: 1312 QKLGTLESQNEQQIKKISSQKEKIKQLKASLEQNNLEIQSINKQ-LEQTKQDLQKEQNKY 1370 Query: 1258 RVQLSAFESKYEQLLDSV----QSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKY 1313 S EQL + Q+ +Q E ++ + L+ +E L+ LQ+ Sbjct: 1371 ENTSGQQSSTIEQLKSKIAELEQAKSQNEQTISSEKQKNSQLEKDQNSIKEDLQTLQQTL 1430 Query: 1314 ADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQ---------- 1363 + N+++ L SEIE K +L N Q+Q Sbjct: 1431 KEKQNELKNLSSEIEKFKEEGKSSKQQIDELSKSNEENLSQINSLNIQIQVFSEQNETIS 1490 Query: 1364 ------EQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDA----EAKVLELTHQLELKD 1413 +Q+I +NE+N+Q + ++N+ E K+ +L ++ Sbjct: 1491 AELTKKDQTISKLNEQNSQFEIDIKTLQMKIREQSEQMNEEKEFQEKKIQQLNSTIDQLK 1550 Query: 1414 SEIYQKTHEYTITLTQRNDEFENVRQQLVEYEK---RIEDLTYEKESELAILRLKMHENA 1470 +I + L ++ E EN +L + +++D+ + S++ L+ ++ E Sbjct: 1551 LQIKSQVETINAKLKEKIQESENAFDELDTTKTELLKLQDIIDGQRSQIITLQNEL-EKL 1609 Query: 1471 NHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQE 1530 N + E E++K E +VKI K AE+ + L+E++ KT+E Q L Q+ Sbjct: 1610 NQLNSQLLE---EKMKA-ESYHVKIQNQEEKIKSNAEMIQVLQEKL-KTSEQQANLLKQQ 1664 Query: 1531 IEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNK 1578 ++ N Q + +K VSF + + QLDN K Sbjct: 1665 LK---------NKQYQEDDQQRETRKSVSFLTSQAEMNKYQLDNQKQK 1703 Score = 177 bits (432), Expect = 2e-42 Identities = 255/1341 (19%), Positives = 582/1341 (43%), Gaps = 108/1341 (8%) Query: 305 EEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSK 364 ++K + E S E N + + + + + ++K+ +N +G+ + S K Sbjct: 88 DKKNKDSESESDEEQNNKQERQSVMAKKQKESDDQHSDKQSDNDDNLLGSSDE--SGDEK 145 Query: 365 KGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLV-D 423 K ++ +N K + ++ +E +Q + A E+ LNK ++ D Sbjct: 146 KEQQ--KKEKQKNKKDKKEQTHLKVENERTSQGLKISAMIRKGADQEV---DLNKPILED 200 Query: 424 KEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQE 483 + ++ D +AQL +E Q+ E L +++ + + Sbjct: 201 SDEEQQQQQENKSSKVMSNTQIDDKLAQLTVEVQRLTEENKL-----KLKEIETLTYTID 255 Query: 484 QLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKT 543 LK+E+ D K+ N +DL KL+ +++ N+E +N+ + + +L+ KQ ++T Sbjct: 256 DLKEEV-DHSKEEN-QDLTTKLQDLNKELESKNNEY---TQNLEQKEKEIQLQQKQAEET 310 Query: 544 IDNF-----SKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNL--QLHLVDYDSGRMIES 596 + +N+E + L E+ + E E +K L + HL+ IE Sbjct: 311 TSQLQLQIQTLKQSANQENLNLNEQFEEKLNNIREQELQKFKLAEENHLIQ------IEQ 364 Query: 597 DVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVC 656 K E+ + E+ +K ++L ++++ ++E+H+L + + + + I ++++Q Sbjct: 365 ITTKHKKEISEI-ESSIKKLTLDSNKRYQQIEEVHLLSIESLK-QQHIKTIEAMKAEQQE 422 Query: 657 SEIKSVH--LEEQIDALSASKKELALVIENLKLDKEQ------LYGTIKDLENDKEDIMN 708 +E KS+ E+ +D L K A+ N KL+ EQ L G IKDLE K Sbjct: 423 NE-KSIRQKYEKHLDRLQDEIK--AIQEANQKLNSEQENKISNLEGQIKDLEKSKNKQNE 479 Query: 709 KLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDL--YIEN 766 +++ + + +K + MS +S + + T++ KI E + Y+E Sbjct: 480 EIKQLKNKLNEKNEKFDIMSTSIVSTESLSVRDSDLKT--TEYIKKIKILEEQIKDYVET 537 Query: 767 IE--SELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELV 824 I+ +E+ + KS + + + M D L + ++L +K + E +++D+ + Sbjct: 538 IKDKNEIIQAKSNLIEEKNKVIQMND---ILIAENEELMKSNTDKIEELDEQILEKDKKI 594 Query: 825 NRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEEN--QNLQISLSDMQQHYNALVEK 882 +L + +D+ + +++L+ + QK + + EN +Q +++ + + + + Sbjct: 595 LQLEIDLDNVKKGFEKVLQQNTDMYMNQKSDTLSQLENLTNKIQEQSNELDEKLDEIAD- 653 Query: 883 ANRTDLAESESTK-YQTQLRDLESNLKRITHE--HQTLIVQKKKE-IEDLEIEFNTQIES 938 N T L + + + Y+ ++ E++LK+ + +TL ++K E I LE+E N + + Sbjct: 654 LNNTILDKDKIIRTYKEKIDQYEADLKQNKEQITSKTLEIEKLTEQIGFLELE-NERFQQ 712 Query: 939 AIRDKKV----LNEKYEKNIEYVTQ-LEAQLQEYKNNIENLNMNV----EELNKMNLELI 989 + +V + +++K+ E + Q L++ + EY IE + + E++N + +++ Sbjct: 713 VLAHTQVERMSIKHEFDKDTELLQQQLKSAMGEYIKKIEMKDFEIQGQAEQINNLVIQM- 771 Query: 990 DKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKI--NNAQVSYMSMVSD-- 1045 + H Q++ T+ E N+I++L+ + K + +I LN+ NN + MV Sbjct: 772 NTH-QEEITKKNQIIEDLNNDISRLSNIQKSQLCQISILNEFCLSNNQNEQILKMVPKRL 830 Query: 1046 ----YESKLAQ-----FTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELK 1096 Y+ + Q F ++ +E++ + + L + +++L+ + Q+DQIK+ + Sbjct: 831 IYRLYKLQANQKFNLIFQEEINTYTQEIETLKENLKKEELKSQDLEESKKNQEDQIKQQE 890 Query: 1097 ETKLTFEMNIPKTEGMI--ISSTIEPMSDDANNVDXXXXXXXXXXXXLK--VQEEEEFIQ 1152 + + + E I++ I+ + D+ + L + ++++ ++ Sbjct: 891 QNIKELHEKLKEIEKRQEEINTEIQNLKDEKEKLTQSIEEDKKVIEELNKSISQKDDELK 950 Query: 1153 ERSVLQEQSAKLNTELQECYT----KIIQLETLNTELTGHDVVNQEQINQLKSK---LEQ 1205 E +Q+Q L +++E K ++ LN + H +Q + L+SK +E+ Sbjct: 951 E---IQQQCVNLKQKIEELEKDVSDKTSEINQLNDLIKNHQEKIDQQEDSLQSKEKTIEE 1007 Query: 1206 LNTENDNLLSTVAELRSSISSA---VDQRGFEIAELWKQHLAQREADFQKTEHELRVQLS 1262 E + + +L + + QR EI ++ ++ Q+E + Q+ ++++ + Sbjct: 1008 TKEELKKKIEVIEKLHEQFNETNQTLGQRAQEIEQII-ENKQQKEKELQEKQNKIDEKQK 1066 Query: 1263 AFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEI 1322 E K E + ++ Q Q + L + E ++ LQEK D + Sbjct: 1067 IIEEKEEIIKENEQKLKQANEQLEENQNAINKLSEQQTQSEAEIKQLQEKLKDTEELLAS 1126 Query: 1323 LRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQ--EQSILNINEENAQLKKS 1380 + +++ + + + +Q+ E+ I +NE+ LK+ Sbjct: 1127 AKENLQNSQKELEQSQESLSQKQKLYDEEHELVQKKAEQITNLEKEISKLNEDLESLKQE 1186 Query: 1381 -SXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQ 1439 +++ ++ + + +I Q E + Q +D+ E ++Q Sbjct: 1187 HKSFIENTNKSHQEQIDSLNQQINQFKQNISENQKQIDQLNSESSQKSNQISDKNEEIQQ 1246 Query: 1440 QLVEYEKRIEDLTYEKES--ELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITE 1497 + E EDL +K++ EL I EN+ + M +++E +R KL++ LN K ++ Sbjct: 1247 LKGKIETLNEDLNSQKKTADELKIQLTAQQENSKEIKNMLQQTESQRDKLMDNLNSKDSQ 1306 Query: 1498 SVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKH 1557 + LN+++ L E+++ K + + ++ + + N EI ++ + + +QK Sbjct: 1307 TAQLNQKLGTLESQNEQQIKKISSQKEKIKQLKASLEQNNLEIQSINKQLEQTKQDLQKE 1366 Query: 1558 VSFASDTKQGRDEQLDNTMNK 1578 + +T + ++ +K Sbjct: 1367 QNKYENTSGQQSSTIEQLKSK 1387 Score = 148 bits (358), Expect = 1e-33 Identities = 254/1277 (19%), Positives = 548/1277 (42%), Gaps = 110/1277 (8%) Query: 383 KSPWSQLSSETLNQDTDKKINKNEIAKLE-MVIQSLNKDLVDKEYVISEKDTXXXXXXXX 441 KS Q+ S+ N+D++ + ++ + K E + + + D ++ + D Sbjct: 79 KSVNFQIFSDKKNKDSESESDEEQNNKQERQSVMAKKQKESDDQHSDKQSDNDDNLLGSS 138 Query: 442 XXGKDTLIAQLQLEHQQHMEGPS-LIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVN--- 497 D Q + E Q++ + H+ E ++ K+ +++ + E+ D+N Sbjct: 139 DESGDEKKEQQKKEKQKNKKDKKEQTHLKVENERTSQGLKISAMIRKGADQEV-DLNKPI 197 Query: 498 VKDLIEKLKSAEEQI-------TQLNDEIDAANKNMIKVKSNHKLKLKQMQK---TIDNF 547 ++D E+ + +E TQ++D++ + ++ +KLKLK+++ TID+ Sbjct: 198 LEDSDEEQQQQQENKSSKVMSNTQIDDKLAQLTVEVQRLTEENKLKLKEIETLTYTIDDL 257 Query: 548 SKVSDSNKEIVR-LTEELHHLSQKVAE--------LEEEKGNLQLHLVDYD---SGRMIE 595 + D +KE + LT +L L++++ LE+++ +QL + S ++ Sbjct: 258 KEEVDHSKEENQDLTTKLQDLNKELESKNNEYTQNLEQKEKEIQLQQKQAEETTSQLQLQ 317 Query: 596 SDVYKKMIEMENLA-----ETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQL 650 K+ ENL E +L I E QKF L +E H++Q + + K +IS++ Sbjct: 318 IQTLKQSANQENLNLNEQFEEKLNNIREQELQKFKLAEENHLIQIEQITTKHK-KEISEI 376 Query: 651 QSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKL 710 +S IK + L+ + L L IE+LK +Q TI+ ++ ++++ + Sbjct: 377 ESS-----IKKLTLDSNKRYQQIEEVHL-LSIESLK---QQHIKTIEAMKAEQQENEKSI 427 Query: 711 QNYIQENMD-LTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIES 769 + ++++D L D+++ I E K+N E+++KI ++ +I++ + Sbjct: 428 RQKYEKHLDRLQDEIKA-----IQEANQKLNSEQENKISN---LEGQIKDLEKSKNKQNE 479 Query: 770 ELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAV 829 E+ + K+++ E +M S E + + S L+ + + I E+++ + + Sbjct: 480 EIKQLKNKLNEKNEKFDIMSTSIVSTESLSVR-DSDLKTTEYI-KKIKILEEQIKDYVET 537 Query: 830 LMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSD-MQQHYNALVEKANRT-- 886 + D + +++ + IE +NK +Q N IL+ EN+ L S +D +++ ++EK + Sbjct: 538 IKDKNEIIQAKSNLIEEKNKVIQM-NDILIAENEELMKSNTDKIEELDEQILEKDKKILQ 596 Query: 887 -----DLAESESTKYQTQLRDLESNLKRITH---EHQTLIVQKKKEIEDLEIEFNTQIES 938 D + K Q D+ N K T E+ T +Q++ D +++ + + Sbjct: 597 LEIDLDNVKKGFEKVLQQNTDMYMNQKSDTLSQLENLTNKIQEQSNELDEKLDEIADLNN 656 Query: 939 AIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMN--LELIDKHVQKQ 996 I DK + Y++ I+ Q EA L++ K I + + +E+L + LEL ++ Q+ Sbjct: 657 TILDKDKIIRTYKEKID---QYEADLKQNKEQITSKTLEIEKLTEQIGFLELENERFQQV 713 Query: 997 QTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTK 1056 + +E +K LL+Q+ + A+ + I ++ + E ++ + Sbjct: 714 LAHTQVERMSIKHEFDKDTELLQQQLKS--AMGEYIKKIEMKDFEIQGQAE-QINNLVIQ 770 Query: 1057 LENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISS 1116 + +EE+ + ++ + D L + + Q QI L E L+ N + M+ Sbjct: 771 MNTHQEEITKKNQIIEDLNNDISRLSNIQKSQLCQISILNEFCLSNNQN-EQILKMVPKR 829 Query: 1117 TIEPMSD-DANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKI 1175 I + AN +++ +E +++ L+ Q + + + QE +I Sbjct: 830 LIYRLYKLQANQKFNLIFQEEINTYTQEIETLKENLKKEE-LKSQDLEESKKNQE--DQI 886 Query: 1176 IQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEI 1235 Q E EL E++ +++ + E++NTE NL +L SI D++ E Sbjct: 887 KQQEQNIKEL-------HEKLKEIEKRQEEINTEIQNLKDEKEKLTQSIEE--DKKVIE- 936 Query: 1236 AELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQE--ETNKIVT--MEQ 1291 EL K ++Q++ + + E++ Q + K E+L V T E + N ++ E+ Sbjct: 937 -ELNKS-ISQKDDELK----EIQQQCVNLKQKIEELEKDVSDKTSEINQLNDLIKNHQEK 990 Query: 1292 VTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXD 1351 + ++ LQ KE+ + +E+ I IE L + + Sbjct: 991 IDQQEDSLQSKEKTIEETKEELKKKIEVIEKLHEQFNETNQTLGQRAQEIEQIIENKQQK 1050 Query: 1352 LRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLEL 1411 + + ++ E+ I EE ++ K + +A K+ E Q E Sbjct: 1051 EKELQEKQNKIDEKQ--KIIEEKEEIIKENEQKLKQANEQLEENQNAINKLSEQQTQSEA 1108 Query: 1412 KDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRI--EDLTYEKESELAILRLKMHEN 1469 + ++ +K + L + +N +++L + ++ + + Y++E EL + + N Sbjct: 1109 EIKQLQEKLKDTEELLASAKENLQNSQKELEQSQESLSQKQKLYDEEHELVQKKAEQITN 1168 Query: 1470 ANHYETMQKESEIERVK-----LIEELNVKITESV-SLNKQVAELNKALEEEVAKTNEMQ 1523 E + ++E +K IE N E + SLN+Q+ + + + E + +++ Sbjct: 1169 LEK-EISKLNEDLESLKQEHKSFIENTNKSHQEQIDSLNQQINQFKQNISENQKQIDQLN 1227 Query: 1524 TALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDA 1583 + + +I N+EI L+ + + + A + K Q +N+ + + Sbjct: 1228 SESSQKSNQISDKNEEIQQLKGKIETLNEDLNSQKKTADELKIQLTAQQENSKEIKNMLQ 1287 Query: 1584 VPRAELDLAMYMLHQRD 1600 ++ D M L+ +D Sbjct: 1288 QTESQRDKLMDNLNSKD 1304 Score = 84.2 bits (199), Expect = 3e-14 Identities = 198/1160 (17%), Positives = 490/1160 (42%), Gaps = 80/1160 (6%) Query: 51 QIKFERAQKCLENAALVSKRIKEHRKATAELLGRPFVP--GISESLANTLKQKEILMEKI 108 Q K ++ + L++ + KE K E++ + +++L ++ E ++E Sbjct: 988 QEKIDQQEDSLQSKEKTIEETKEELKKKIEVIEKLHEQFNETNQTLGQRAQEIEQIIEN- 1046 Query: 109 KQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNALSVLQVKMKIM 168 KQ KE + + + + ++E NA++ L + Sbjct: 1047 KQQKEKELQEKQNKIDEKQKIIEEKEEIIKENEQKLKQANEQLEENQNAINKLSEQQTQS 1106 Query: 169 ETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAM 228 E I LQEK+ + ++++ A+ KQ++ + + Sbjct: 1107 EAEIKQLQEKLKDTEELL-----ASAKENLQNSQKELEQSQESLSQKQKLYDEEHELVQK 1161 Query: 229 EAEWKDEKQRLLKDIESKDVRISSLEEANK-LLEAARFEISLEHSKLAQELEQXXXXXXX 287 +AE + L K+I + + SL++ +K +E + L Q++ Q Sbjct: 1162 KAE---QITNLEKEISKLNEDLESLKQEHKSFIENTNKSHQEQIDSLNQQINQFKQNISE 1218 Query: 288 XXXXXXXLAKQSIEPS---CEEKTEIEE-KGSLEIANMTELTKKIELLEHLNCQI---RQ 340 L +S + S ++ EI++ KG +E N +L + + + L Q+ ++ Sbjct: 1219 NQKQIDQLNSESSQKSNQISDKNEEIQQLKGKIETLN-EDLNSQKKTADELKIQLTAQQE 1277 Query: 341 TNKELENKL-ATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTD 399 +KE++N L T K + + + K S T ++S Q + +Q Sbjct: 1278 NSKEIKNMLQQTESQRDKLMDNLNSKDSQTAQLNQKLGT---LESQNEQQIKKISSQKEK 1334 Query: 400 KKINKNEIAKLEMVIQSLNKDLVD-KEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQ 458 K K + + + IQS+NK L K+ + E++ + L +++ Q Sbjct: 1335 IKQLKASLEQNNLEIQSINKQLEQTKQDLQKEQNKYENTSGQQSSTIEQLKSKIAELEQA 1394 Query: 459 HMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDE 518 + I + + +++ K Q +K++L + +K+ +LK+ +I + +E Sbjct: 1395 KSQNEQTI--SSEKQKNSQLEKDQNSIKEDL--QTLQQTLKEKQNELKNLSSEIEKFKEE 1450 Query: 519 IDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEK 578 ++ + + ++ +++ L Q+ S+ N+ I + EL Q +++L E+ Sbjct: 1451 GKSSKQQIDELSKSNEENLSQINSLNIQIQVFSEQNETI---SAELTKKDQTISKLNEQN 1507 Query: 579 GNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAI-SLLESQKFDLVQELHILQQKY 637 + +D + +M + ++M E + E +++ + S ++ K + ++ + K Sbjct: 1508 SQFE---IDIKTLQMKIREQSEQMNEEKEFQEKKIQQLNSTIDQLKLQIKSQVETINAK- 1563 Query: 638 DEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIK 697 +++K+ + + ++ + + L++ ID + L +E L QL Sbjct: 1564 --LKEKIQESENAFDELDTTKTELLKLQDIIDGQRSQIITLQNELEKLNQLNSQLLEEKM 1621 Query: 698 DLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKI 757 E+ I N+ + I+ N ++ L++ K SE A + ++ Q Q + Sbjct: 1622 KAESYHVKIQNQ-EEKIKSNAEMIQVLQEKL--KTSEQQANLLKQQLKNKQYQEDDQQRE 1678 Query: 758 QERDLYIENIESELSKYK--SRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSE 815 + + ++E++KY+ ++ + ++ A + + SL + QL ++EKQ S Sbjct: 1679 TRKSVSFLTSQAEMNKYQLDNQKQKWDQQEAEYKIKINSLNAQIQQL---IEEKQ---SN 1732 Query: 816 YTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQH 875 +++ + R +V++D ++ + + L ++ ++++ ++ + + E + + ++++ + Sbjct: 1733 IDMKKSFMKERESVVVDKEKAL-RDLKQLYAQSRKNEESLEQKISEMEKVILNMNQEIES 1791 Query: 876 YNALVEKANRTDLAESESTKYQ-TQLRDLES-NL-KRITHEHQTLIVQKKKEIEDLEIEF 932 + +AN+ + + KY+ +Q DL S NL K + E + +K+ ++ E Sbjct: 1792 LRTQLIRANQQIEQMAYARKYEASQYADLRSANLSKALQQESLPTLNNIQKQGSNMG-EL 1850 Query: 933 N-TQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDK 991 N +QI + K ++ + ++ + +Q+ + +N N+++ + E+ + Sbjct: 1851 NLSQINHSFTQKDAEDDNI-MLADLANEILSLIQQ--GDQQNNEANLKQSASVGGEIANS 1907 Query: 992 HVQKQQTQSPDYTEQYINEINKLNALLKQK-DEEIIAL---NQKINNAQV-SYMSMVSDY 1046 + T +P+ Q ++ ++K+ ++ QK ++++ L N + N AQ+ ++ ++ Sbjct: 1908 --SQFVTFTPEDENQILSSLSKIKNIIAQKLSQDLVNLQSKNSESNRAQLRKHLLIIIKV 1965 Query: 1047 ESKLAQF---TTKLENMEEEMQRVSKQL-LDSKQ-----HNEELQILVREQDDQIKELKE 1097 ++ + Q+ T ++N +E+ +++Q LD + +++ + + D+ I++ Sbjct: 1966 QNIIHQWLYITFFIQNNIKELNNLNQQYGLDRWKKVRGGQADKINLQTKAIDEFIQQFSR 2025 Query: 1098 TKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVL 1157 +T E K S T+ S + ++ E + F ++ + Sbjct: 2026 VLITLE---SKNNTSDSSFTVYAESTSSRQEFLKVKNSSRLDDLIRAMELQGFSEQ--LP 2080 Query: 1158 QEQSAKLNTELQECYTKIIQ 1177 Q +K ++E+Q+ IIQ Sbjct: 2081 NYQRSKTSSEIQQNLKGIIQ 2100 >UniRef50_UPI0000D8E0D4 Cluster: UPI0000D8E0D4 related cluster; n=1; Danio rerio|Rep: UPI0000D8E0D4 UniRef100 entry - Danio rerio Length = 2127 Score = 184 bits (449), Expect = 1e-44 Identities = 311/1608 (19%), Positives = 681/1608 (42%), Gaps = 120/1608 (7%) Query: 49 ERQIKFERAQK-CLENAALVSKRIKEHRKATAELLGR--PFVPGISESLANTLKQKEILM 105 + +K + QK LE+ SK+IKE + + L + + E LA K+ ++ Sbjct: 205 DEDLKMMKLQKQVLEDEK--SKKIKEEIQNERQNLEKMTEALKEEREDLAEETKKNNQVL 262 Query: 106 EKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNALSVLQVKM 165 +++K ++ S+ + Q DV + ++ +++ L LQ ++ Sbjct: 263 DEMK----VANESTLADILREKSNLEEMRENISKQTEDVENKKENLRLREDELRQLQAEI 318 Query: 166 KIMETTILDLQEKIN-EKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQEN 224 + I +EKIN E ++ K+ +D +Q T M + Sbjct: 319 HKQQREIE--KEKINIESERAAIIKDVEDLQHKNLQQELEKEKEIIMKDRNKQQTNMNDI 376 Query: 225 FIAMEAEWK----------DEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKL 274 M+ E K ++KQ + K+ ++ D SL+E K ++ + E +KL Sbjct: 377 METMKNERKQLDKDKEEMEEQKQEMEKERDNMDQSRKSLDEDQKKMKLQKQMFEEEKNKL 436 Query: 275 AQ---ELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELL 331 Q ELE+ +Q +E EE ++ + S+ + E+ + I L Sbjct: 437 EQMKIELEREADEISKIKEETQN-KRQRLEKMTEELINLQREKSI----LEEMRENISKL 491 Query: 332 EHLNCQIRQTNKELENKLATMGTE-SKAVSSPSKKGSPLISRKSG-----RNTASKMKSP 385 + ++ +K E++L + TE K S + + + S ++ +N +++K Sbjct: 492 KEYIDNEKEKSKLREDELKKLQTEVQKQQSKIDMEKTNIESERAAMIREKQNMMTELKKK 551 Query: 386 WSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISE-KDTXXXXXXXXXXG 444 + + T+K++ N+ L +++L + L+D E K Sbjct: 552 SEDVEIQMKEILTEKELLHNDRKLLTRDVENLQQKLIDLERDSKRLKLDREAFKEDLEKQ 611 Query: 445 KDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQL--KQELNDEIKDVNVKDLI 502 K+ +A++Q E + + I T +++EI +EQ+ KQ+ D++K +++L Sbjct: 612 KENTLAEIQKEREDVEKMNENI-----TREMHEIKHQEEQMNQKQDELDQLK-TEIQNLQ 665 Query: 503 EKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTE 562 ++L+ +E I + D K+ + + + +L Q++ I N + + KEI+ Sbjct: 666 QELEKEKEII--MKDRKMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEIIMKAR 723 Query: 563 ELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQ 622 L ++ +EL++++ N+ +++ + D K+ +E E E + + Q Sbjct: 724 S--QLDRRQSELDKQQTNMN-DIMETMKNERKQLDKDKEEME-EQKQEMEKEMKENISKQ 779 Query: 623 KFDLVQELHILQQKYDEVEDKLADISQLQSDQVC--SEIKSVHLEEQIDALSASKKEL-- 678 D+ +E ++ + DE+E A+I + QS+ S I+ E + + L K EL Sbjct: 780 TEDIEKEKDKIRLREDELEQLQAEIHKQQSETEIEKSNIEREAFENEKEELKQMKTELER 839 Query: 679 -ALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLA 737 A IE +KL+ + ++++ D + MN + + +N + ++ +K EK + + Sbjct: 840 EADEIEKIKLETQHERQRVEEMTADFMETMNNERKQLDKNKVMIEE-QKQEMEKKRDDMD 898 Query: 738 KINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLER 797 + ++ ++E +E ++ L + I +++E ++ R +LE+ Sbjct: 899 QSRKSLDEDLKMMKAQKQVLEEEKNKLEQMKIGLEREADEISKIKEE---TQNERQNLEK 955 Query: 798 KADQL---GSYLQEKQKAYSEYTIQEDELVNR--LAVLMDHDRVVEKQLLEIEHENKELQ 852 A+ L YL E+ K ++ + + ++ N LA L R++E+ I + ++++ Sbjct: 956 MANALKEEREYLAEEIKRKNQ-VLDKIKVANESTLADLQKEKRILEEMRENISKQIEDIE 1014 Query: 853 ---KKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKR 909 +K+++ +E + LQ + Q+ E+ + E + ++ ES L + Sbjct: 1015 NEKEKSKLREDELKKLQTEVQKQQKRDTISKEERRTNERLNEEINIQKVNQQNRESELAK 1074 Query: 910 ----ITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLE-AQL 964 I + Q + + K+EI E Q ++K+ L + + N++ + E +L Sbjct: 1075 LQEDILQQQQEMDEKTKEEINYDREEIYRQRTELNKEKETLKQMHTSNLKQPEKKEREEL 1134 Query: 965 QEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEE 1024 ++ K+ I +VE ++ +ID +QK + + TE+ + + L+ Q + + Sbjct: 1135 EQLKDEINREKEDVEIRRELVEAVID--IQKYKEELQSVTEELLTKKRDLD----QLNSD 1188 Query: 1025 IIALNQKINNAQVSYMSMVSDYES---KLAQFTTKLENMEEEMQR---VSKQLLDSKQHN 1078 + L Q I + + ++ E +L + LE ++E++ + +++ + K Sbjct: 1189 VQDLRQTIEEINIQHGKKRAELEGIGFELKKGEQLLEKQKDELKENGWIVEEIKNKKDSL 1248 Query: 1079 EELQI-LVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXX 1137 E++ + ++R+ +D KE + KL E+ + + + ++I+ ++ + + Sbjct: 1249 EKINMEILRKNEDMDKE--KGKLRSELQRQRED---LETSIQKLTHEKREIKNQIEQEKK 1303 Query: 1138 XXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQIN 1197 +K E + R L E QE + +LE +LT +E+ N Sbjct: 1304 DLQNMKSNLERQLESLRHEKANVEGLLEKEKQELKQEKKELEDQMMDLTREKQETEEERN 1363 Query: 1198 Q---LKSKLEQLNTE---NDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQ 1251 LK++LE L + N+N + + R I + + +L + +A RE + + Sbjct: 1364 NLMALKNQLEDLKEQIQNNENAKHLLEQERKDIDKQKQELQKQADDLDMRMIAHRE-NVE 1422 Query: 1252 KTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQE 1311 ++ L + E K ++L +E+ + + ++ LQN++Q++ + + + Sbjct: 1423 MSKRSLDEEKKLLEQKANEILRQRDDLEKEKEDMMKKWNKLDVLQNEMQNENKAMEEI-- 1480 Query: 1312 KYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNIN 1371 KY +++ R+EI E+ DL +N+S Q + + I NIN Sbjct: 1481 KY-----ELDGKRNEINKEQQRLEKEELDIERQKIADEQDLLIQNKSELQNENERIRNIN 1535 Query: 1372 EENAQLKKSSXXXXXXXXXXXXRVNDAEAKVL-----ELTHQLELKDSEIYQKTHEYTIT 1426 E+ L++ R+++ +A+V +LT Q E+K+++ + Sbjct: 1536 EQRDLLEQEKEDINHEWTQLQQRIDEFDAQVSKQKEEDLTKQKEMKENK--SELQNENER 1593 Query: 1427 LTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVK 1486 + N+ + R+ L E E +E +E++ ++ +K E ++KE E E + Sbjct: 1594 IRNLNEIIKKERETLKEMEAHLEKKKSLEETKANVIEMKTKAEP---EEIKKEKEKENEE 1650 Query: 1487 LIEELNVKITESVSLNKQVAELNKALEEEVAKTNE--MQTALENQEIEIVTLNDE-ITNL 1543 EE + + + ++ + +EEE ++ + QT LE +IE +E +T Sbjct: 1651 EEEEEEEEKEDLEKMKSEIMTQRQQMEEERSELDNKIKQTDLERHDIENSKQKEEDLTKQ 1710 Query: 1544 QNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDL 1591 + M S + + + E++ KE + V RA++++ Sbjct: 1711 KKMEEERKSLEETKIKIIEMKTKTEPEKIKKEKEKE-EEEVMRAKVEI 1757 Score = 165 bits (402), Expect = 7e-39 Identities = 278/1503 (18%), Positives = 646/1503 (42%), Gaps = 127/1503 (8%) Query: 152 KEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXX 211 K+K+N L+ +Q + + +E ++ +++E E N+ Sbjct: 610 KQKENTLAEIQKEREDVEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELE 669 Query: 212 EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISS-LEEANKLLEAARFEISLE 270 ++ + M + + I + E ++KQ L ++++ + LE+ +++ AR ++ Sbjct: 670 KEKEIIMKDRKMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEIIMKARSQLDRR 729 Query: 271 HSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTE-LTK--- 326 S+L ++ L K E E+K E+E++ I+ TE + K Sbjct: 730 QSELDKQQTNMNDIMETMKNERKQLDKDKEEME-EQKQEMEKEMKENISKQTEDIEKEKD 788 Query: 327 KIEL----LEHLNCQIRQTNKELENKLATMGTES-KAVSSPSKKGSPLISRKSGRNTASK 381 KI L LE L +I + E E + + + E+ + K+ + R++ K Sbjct: 789 KIRLREDELEQLQAEIHKQQSETEIEKSNIEREAFENEKEELKQMKTELEREADEIEKIK 848 Query: 382 MKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXX 441 +++ + E + D + +N NE +L+ NK +++++ EK Sbjct: 849 LETQHERQRVEEMTADFMETMN-NERKQLDK-----NKVMIEEQKQEMEKKRDDMDQSRK 902 Query: 442 XXGKDTLIAQLQLEHQQHMEGP-SLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVN-VK 499 +D + + Q + + + + +G E +EI+K++E+ + E + K N +K Sbjct: 903 SLDEDLKMMKAQKQVLEEEKNKLEQMKIGLERE-ADEISKIKEETQNERQNLEKMANALK 961 Query: 500 DLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVR 559 + E L ++ Q+ D+I AN++ + K L++M++ I + ++ KE + Sbjct: 962 EEREYLAEEIKRKNQVLDKIKVANESTLADLQKEKRILEEMRENISKQIEDIENEKEKSK 1021 Query: 560 LTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAE--TRLKAIS 617 L E+ L + E+++++ + + + + ++ + + +N +L+ Sbjct: 1022 LRED--ELKKLQTEVQKQQKRDTISKEERRTNERLNEEINIQKVNQQNRESELAKLQEDI 1079 Query: 618 LLESQKFD--LVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASK 675 L + Q+ D +E++ +++ +L + S +K +E+ + L K Sbjct: 1080 LQQQQEMDEKTKEEINYDREEIYRQRTELNKEKETLKQMHTSNLKQPEKKER-EELEQLK 1138 Query: 676 KELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISEL 735 E+ E++++ +E + I D++ KE++ + + + + DL D+L + + + Sbjct: 1139 DEINREKEDVEIRRELVEAVI-DIQKYKEELQSVTEELLTKKRDL-DQLNS-DVQDLRQT 1195 Query: 736 LAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSL 795 + +IN + K GI ++++ + +E + EL + + ++ +E + Sbjct: 1196 IEEINIQHGKKRAELEGIGFELKKGEQLLEKQKDELKENGWIVEEIKNKKDSLEKINMEI 1255 Query: 796 ERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKN 855 RK + + +EK K SE Q ++L + L R ++ Q IE E K+LQ Sbjct: 1256 LRKNEDMD---KEKGKLRSELQRQREDLETSIQKLTHEKREIKNQ---IEQEKKDLQNMK 1309 Query: 856 QILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQ 915 L + ++L+ ++++ L+EK + + E + + Q+ DL K+ T E + Sbjct: 1310 SNLERQLESLRHEKANVE----GLLEKEKQE--LKQEKKELEDQMMDLTRE-KQETEEER 1362 Query: 916 TLIVQKKKEIEDL--EIEFNTQIESAI-RDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIE 972 ++ K ++EDL +I+ N + + +++K ++++ ++ + L+ ++ ++ N+E Sbjct: 1363 NNLMALKNQLEDLKEQIQNNENAKHLLEQERKDIDKQKQELQKQADDLDMRMIAHRENVE 1422 Query: 973 NLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQ-- 1030 +++E K+ LE + +Q+ E + + NKL+ L + E A+ + Sbjct: 1423 MSKRSLDEEKKL-LEQKANEILRQRDDLEKEKEDMMKKWNKLDVLQNEMQNENKAMEEIK 1481 Query: 1031 --------KINNAQVSY--------MSMVSDYESKLAQFTTKLENMEEEMQRVSKQ--LL 1072 +IN Q ++D + L Q ++L+N E ++ +++Q LL Sbjct: 1482 YELDGKRNEINKEQQRLEKEELDIERQKIADEQDLLIQNKSELQNENERIRNINEQRDLL 1541 Query: 1073 DSKQHN-----EELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANN 1127 + ++ + +LQ + E D Q+ + KE LT + + + + S ++ ++ N Sbjct: 1542 EQEKEDINHEWTQLQQRIDEFDAQVSKQKEEDLTKQKEMKENK-----SELQNENERIRN 1596 Query: 1128 VDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTG 1187 ++ ++E E ++++ L+E A + E TK + E + E Sbjct: 1597 LNEIIKKERET-----LKEMEAHLEKKKSLEETKANVI----EMKTKA-EPEEIKKEKEK 1646 Query: 1188 HDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQRE 1247 + +E+ + K LE++ +E + E RS + + + Q E ++ ++ Q+E Sbjct: 1647 ENEEEEEEEEEEKEDLEKMKSEIMTQRQQMEEERSELDNKIKQTDLERHDI--ENSKQKE 1704 Query: 1248 ADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLR 1307 D K ++ ++ + S +E KI+ M+ T + ++KE+ Sbjct: 1705 EDLTK----------------QKKMEEERKSLEETKIKIIEMKTKTEPEKIKKEKEKEEE 1748 Query: 1308 NLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQ-- 1365 + ++ +Q+E +RSEI+ E+ +++E +Q E+ Sbjct: 1749 EVMRAKVEIKSQLERVRSEIDHEQKKL-NDDKKMIEQEKEDLEKMKSEIMKQRQQMEEER 1807 Query: 1366 -----SILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLE-----LKDSE 1415 I + E ++ S ++ + ++ E+ +++ LK+ E Sbjct: 1808 SELDNKIKQTDLERHDIENSKEIVQKLMVENKAKLQNENERIKEMDEEIKKEKETLKEME 1867 Query: 1416 IYQKTHE----YTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENAN 1471 + + + I TQR + E++ + + K+ +DL +++ L +++ E + Sbjct: 1868 AHLRKEKEEMRSVIEETQRRQK-EDLEKMSTDVNKQNQDLMNQRDLLKQKLMVEVEEQKH 1926 Query: 1472 HYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALE-NQE 1530 + ++E +IER K+ +E ++ I L + E + ++ ++ + NE + E ++E Sbjct: 1927 EIQFQKEELDIERQKIADEQDLLIQNKSELQNE-NEQDLLIQNKIEQQNENERIKEMDEE 1985 Query: 1531 I--EIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAE 1588 I E TL + NLQ S I++ D ++G + + KE ++P+ E Sbjct: 1986 IKKERETLKEMEVNLQKEKEEIESVIEETQRRKEDLEKGETVEKHTDIIKEYTTSIPKEE 2045 Query: 1589 LDL 1591 ++ Sbjct: 2046 YEI 2048 Score = 165 bits (401), Expect = 9e-39 Identities = 214/1110 (19%), Positives = 485/1110 (43%), Gaps = 84/1110 (7%) Query: 503 EKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTE 562 E L ++ Q+ DE+ AN++ + + L++M++ I ++ ++ KE +RL E Sbjct: 7 EDLSEDAKRKNQVLDEMKVANESTLADILRERSNLQEMRENISKQTEDVENKKEKIRLRE 66 Query: 563 E-LHHLSQKV----AELEEEKGNLQLH---LVDYDSGRMIES-DVYKKMIEMENLAETRL 613 E L L ++ +E E+EK N++ +++ D R ES + ++ E E ++ Sbjct: 67 EKLKQLQAEIHKQQSETEKEKSNIERERAAIINLD--RDAESLKLDREAFENEKEELKQM 124 Query: 614 KAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSA 673 K E++ D+ + ++QK DE++ +I LQ Q + K + ++++ + Sbjct: 125 KTELEREAEIHDIKHQEEQMKQKQDELDQLKTEIQNLQ--QELEKEKEIIMKDR----NK 178 Query: 674 SKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEK-- 731 K+E + ++ +K + K L+ D + M KLQ + E+ E++ E+ Sbjct: 179 DKEETEEQKQEMEKEKHDFDQSRKSLDEDLK--MMKLQKQVLEDEKSKKIKEEIQNERQN 236 Query: 732 ISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDR 791 + ++ + E + + + + E + E+ +++ + KS + + E+I+ + Sbjct: 237 LEKMTEALKEEREDLAEETKKNNQVLDEMKVANESTLADILREKSNLEEMRENISKQTE- 295 Query: 792 RYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHEN--K 849 +E K + L E ++ +E Q+ E+ + + K + +++H+N + Sbjct: 296 --DVENKKENLRLREDELRQLQAEIHKQQREIEKEKINIESERAAIIKDVEDLQHKNLQQ 353 Query: 850 ELQKKNQILLEENQNLQISLSD-MQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLK 908 EL+K+ +I++++ Q +++D M+ N + + E + + + + +++ + K Sbjct: 354 ELEKEKEIIMKDRNKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKERDNMDQSRK 413 Query: 909 RITHEHQTLIVQK------KKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEA 962 + + + + +QK K ++E ++IE + + + K+ K ++ +E +T+ Sbjct: 414 SLDEDQKKMKLQKQMFEEEKNKLEQMKIELEREADEISKIKEETQNKRQR-LEKMTEELI 472 Query: 963 QLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKD 1022 LQ K+ +E + N+ +L E ID +K + + +E+ KL ++++ Sbjct: 473 NLQREKSILEEMRENISKLK----EYIDNEKEKSKLRE--------DELKKLQTEVQKQQ 520 Query: 1023 EEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRV--SKQLL--DSKQHN 1078 +I + + N + +M+ + ++ + + K E++E +M+ + K+LL D K Sbjct: 521 SKI---DMEKTNIESERAAMIREKQNMMTELKKKSEDVEIQMKEILTEKELLHNDRKLLT 577 Query: 1079 EELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXX 1138 +++ L ++ D ++ K KL E E +T+ + + +V+ Sbjct: 578 RDVENLQQKLIDLERDSKRLKLDREAFKEDLEKQ-KENTLAEIQKEREDVEKMNENITRE 636 Query: 1139 XXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKI-IQLETLNTELTGHDVVNQ-EQI 1196 +K QEE + + Q++ +L TE+Q ++ + E + + H++ +Q EQ+ Sbjct: 637 MHEIKHQEE-----QMNQKQDELDQLKTEIQNLQQELEKEKEIIMKDRKMHEIKHQEEQM 691 Query: 1197 NQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHE 1256 NQ + +L+QL TE NL + + + I A Q +EL KQ D +T Sbjct: 692 NQKQDELDQLKTEIQNLQQELEKEKEIIMKARSQLDRRQSELDKQQTNMN--DIMETMKN 749 Query: 1257 LRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADV 1316 R QL + + E+ ++ +E +K E + ++K++ +E+ L LQ + Sbjct: 750 ERKQLDKDKEEMEEQKQEMEKEMKENISK--QTEDIEKEKDKIRLREDELEQLQAEIHKQ 807 Query: 1317 INQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXD------LRT--ENQSYKQMQEQSIL 1368 ++ EI +S IE E D L T E Q ++M + Sbjct: 808 QSETEIEKSNIEREAFENEKEELKQMKTELEREADEIEKIKLETQHERQRVEEMTADFME 867 Query: 1369 NINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDS------EIYQKTHE 1422 +N E QL K+ + +D + L L++ + E K + Sbjct: 868 TMNNERKQLDKNKVMIEEQKQEMEKKRDDMDQSRKSLDEDLKMMKAQKQVLEEEKNKLEQ 927 Query: 1423 YTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEI 1482 I L + DE ++++ + +E + + E L ++ + ++ +E Sbjct: 928 MKIGLEREADEISKIKEETQNERQNLEKMANALKEEREYLAEEIKRKNQVLDKIKVANES 987 Query: 1483 ERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITN 1542 L +E + +++KQ+ ++ E+E +K E + E++ D I+ Sbjct: 988 TLADLQKEKRILEEMRENISKQIEDIEN--EKEKSKLREDELKKLQTEVQKQQKRDTISK 1045 Query: 1543 LQNMVRASSSKIQKHVSFASDTKQGRDEQL 1572 + R ++ ++ + ++ +Q R+ +L Sbjct: 1046 EE---RRTNERLNEEINIQKVNQQNRESEL 1072 Score = 159 bits (387), Expect = 4e-37 Identities = 216/1147 (18%), Positives = 499/1147 (43%), Gaps = 98/1147 (8%) Query: 461 EGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEID 520 E ++I++ + E + + E K+EL ++ + I +K EEQ+ Q DE+D Sbjct: 93 ERAAIINLDRDAESLKLDREAFENEKEELKQMKTELEREAEIHDIKHQEEQMKQKQDELD 152 Query: 521 AANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGN 580 + ++ + + + + K + + ++ K+ + +E H Q L+E+ Sbjct: 153 QLKTEIQNLQQELEKEKEIIMKDRNKDKEETEEQKQ--EMEKEKHDFDQSRKSLDEDLKM 210 Query: 581 LQLHLVDYDSGRMIESDVYKKM-IEMENLAETRLKAISLLESQKFDLVQELHILQQKYDE 639 ++L +++E + KK+ E++N + K L+ ++ DL +E Q DE Sbjct: 211 MKL------QKQVLEDEKSKKIKEEIQNERQNLEKMTEALKEEREDLAEETKKNNQVLDE 264 Query: 640 V----EDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGT 695 + E LADI + +S+ E++ ++ +Q + + K+ L L + L+ + +++ Sbjct: 265 MKVANESTLADILREKSN--LEEMRE-NISKQTEDVENKKENLRLREDELRQLQAEIHKQ 321 Query: 696 IKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKI-------- 747 +++E +K +I ++ I++ DL K + EK E++ K +++Q+ + Sbjct: 322 QREIEKEKINIESERAAIIKDVEDLQHKNLQQELEKEKEIIMKDRNKQQTNMNDIMETMK 381 Query: 748 --QTQFGIDAKIQER------------DLYIENIESELSKYKSRICRLEESIAVMEDRRY 793 + Q D + E D ++++ + K K + EE +E + Sbjct: 382 NERKQLDKDKEEMEEQKQEMEKERDNMDQSRKSLDEDQKKMKLQKQMFEEEKNKLEQMKI 441 Query: 794 SLERKADQLGSYLQEKQKAYSEYTIQEDELVN---RLAVLMDHDRVVE--KQLLEIEHEN 848 LER+AD++ +E Q +EL+N ++L + + K+ ++ E E Sbjct: 442 ELEREADEISKIKEETQNKRQRLEKMTEELINLQREKSILEEMRENISKLKEYIDNEKEK 501 Query: 849 KELQ----KKNQILLEENQN-LQISLSDMQQHYNALV-EKANRTDLAESESTKYQTQLRD 902 +L+ KK Q +++ Q+ + + ++++ A++ EK N + +S + Q+++ Sbjct: 502 SKLREDELKKLQTEVQKQQSKIDMEKTNIESERAAMIREKQNMMTELKKKSEDVEIQMKE 561 Query: 903 LESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEA 962 + + K + H + L+ + + ++ I+ + D++ E EK E A Sbjct: 562 ILTE-KELLHNDRKLLTRDVENLQQKLIDLERDSKRLKLDREAFKEDLEKQKENTL---A 617 Query: 963 QLQEYKNNIENLNMNV-EELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQK 1021 ++Q+ + ++E +N N+ E++++ KH ++Q Q D +Q EI L L +K Sbjct: 618 EIQKEREDVEKMNENITREMHEI------KHQEEQMNQKQDELDQLKTEIQNLQQEL-EK 670 Query: 1022 DEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEEL 1081 ++EII ++K++ + M + + +L Q T+++N+++E+++ + ++ ++ + Sbjct: 671 EKEIIMKDRKMHEIKHQEEQM-NQKQDELDQLKTEIQNLQQELEKEKEIIMKARSQLDRR 729 Query: 1082 QILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXX 1141 Q + +Q + ++ ET + K + + E + N+ Sbjct: 730 QSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKEMKENISKQTEDIEKEKDK 789 Query: 1142 LKVQEEEEFIQERSVLQEQS----AKLNTELQECYTKIIQLETLNTELTGHDVVNQEQIN 1197 ++++E+E + + ++QS K N E + + +L+ + TEL ++I Sbjct: 790 IRLREDELEQLQAEIHKQQSETEIEKSNIEREAFENEKEELKQMKTELER----EADEIE 845 Query: 1198 QLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHEL 1257 ++K + + + + + E ++ +D+ I E KQ + ++ D ++ L Sbjct: 846 KIKLETQHERQRVEEMTADFMETMNNERKQLDKNKVMIEE-QKQEMEKKRDDMDQSRKSL 904 Query: 1258 RVQLSAFESKYEQL------LDSVQSSTQEETNKIVTMEQVT--------SLQNKLQDKE 1303 L +++ + L L+ ++ + E ++I +++ T + N L+++ Sbjct: 905 DEDLKMMKAQKQVLEEEKNKLEQMKIGLEREADEISKIKEETQNERQNLEKMANALKEER 964 Query: 1304 EHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQ 1363 E+L ++ V+++I++ + D+ E + K ++ Sbjct: 965 EYLAEEIKRKNQVLDKIKVANESTLADLQKEKRILEEMRENISKQIEDIENEKEKSK-LR 1023 Query: 1364 EQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEY 1423 E + + E Q ++ R+N+ E + ++ Q ++SE+ K E Sbjct: 1024 EDELKKLQTE-VQKQQKRDTISKEERRTNERLNE-EINIQKVNQQ--NRESEL-AKLQED 1078 Query: 1424 TITLTQRNDE--FENVRQQLVEYEKRIEDLTYEKES--ELAILRLKMHENANHYETMQKE 1479 + Q DE E + E ++ +L EKE+ ++ LK E E Q + Sbjct: 1079 ILQQQQEMDEKTKEEINYDREEIYRQRTELNKEKETLKQMHTSNLKQPEKKEREELEQLK 1138 Query: 1480 SEIERVKLIEELNVKITESV-SLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLND 1538 EI R K E+ ++ E+V + K EL EE + K ++ N +++ + Sbjct: 1139 DEINREKEDVEIRRELVEAVIDIQKYKEELQSVTEELLTKKRDLDQL--NSDVQDLRQTI 1196 Query: 1539 EITNLQN 1545 E N+Q+ Sbjct: 1197 EEINIQH 1203 Score = 142 bits (344), Expect = 7e-32 Identities = 230/1174 (19%), Positives = 521/1174 (44%), Gaps = 96/1174 (8%) Query: 215 KQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKL 274 K++ ++N M K+E++ L ++I+ K+ + ++ AN E+ ++ E ++ Sbjct: 943 KEETQNERQNLEKMANALKEEREYLAEEIKRKNQVLDKIKVAN---ESTLADLQKE-KRI 998 Query: 275 AQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHL 334 +E+ + +K + + +TE++++ + + E L E + Sbjct: 999 LEEMRENISKQIEDIENEKEKSKLREDELKKLQTEVQKQQKRDTISKEERRTNERLNEEI 1058 Query: 335 NCQ-IRQTNKELE-NKLATMGTESKAVSSPSKKGSPLISRKS---GRNTASKMKSPWSQL 389 N Q + Q N+E E KL + + K R+ R +K K Q+ Sbjct: 1059 NIQKVNQQNRESELAKLQEDILQQQQEMDEKTKEEINYDREEIYRQRTELNKEKETLKQM 1118 Query: 390 SSETLNQDTDKKINKNEIAKLEMVIQS----LNKDLVDKEYVISEKDTXXXXXXXXXXGK 445 + L Q K+ + E K E+ + + ++LV+ I + K Sbjct: 1119 HTSNLKQPEKKEREELEQLKDEINREKEDVEIRRELVEAVIDIQKYKEELQSVTEELLTK 1178 Query: 446 DTLIAQLQLEHQ---QHMEGPSLIHVGTNTEDVNEIA---KVQEQLKQELNDEIKDVNVK 499 + QL + Q Q +E ++ H G ++ I K EQL ++ DE+K+ Sbjct: 1179 KRDLDQLNSDVQDLRQTIEEINIQH-GKKRAELEGIGFELKKGEQLLEKQKDELKENGW- 1236 Query: 500 DLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTID-NFSKVSDSNKEIV 558 ++E++K+ ++ + ++N EI N++M K K + +L++ ++ ++ + K++ +EI Sbjct: 1237 -IVEEIKNKKDSLEKINMEILRKNEDMDKEKGKLRSELQRQREDLETSIQKLTHEKREIK 1295 Query: 559 RLTEE--------LHHLSQKVAELEEEKGNLQ-LHLVDYDSGRMIESDVYKKMIEM---E 606 E+ +L +++ L EK N++ L + + + ++ +M+++ + Sbjct: 1296 NQIEQEKKDLQNMKSNLERQLESLRHEKANVEGLLEKEKQELKQEKKELEDQMMDLTREK 1355 Query: 607 NLAETRLKAISLLESQKFDLVQEL-------HILQQKYDEVEDKLADISQLQSDQVCSEI 659 E + L++Q DL +++ H+L+Q+ +++ + ++ Q Q+D + ++ Sbjct: 1356 QETEEERNNLMALKNQLEDLKEQIQNNENAKHLLEQERKDIDKQKQEL-QKQADDL--DM 1412 Query: 660 KSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQ--NYIQEN 717 + + E ++ SK+ L + L+ ++ DLE +KED+M K + +Q Sbjct: 1413 RMIAHRENVEM---SKRSLDEEKKLLEQKANEILRQRDDLEKEKEDMMKKWNKLDVLQNE 1469 Query: 718 MDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAK--IQERDLYIENIESELSKYK 775 M +K + ++ +IN E+Q + + I+ + E+DL I+N +SEL Sbjct: 1470 MQNENKAMEEIKYELDGKRNEINKEQQRLEKEELDIERQKIADEQDLLIQN-KSELQNEN 1528 Query: 776 SRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDR 835 RI + E ++E + + + QL + E S+ Q++E + + + ++ Sbjct: 1529 ERIRNINEQRDLLEQEKEDINHEWTQLQQRIDEFDAQVSK---QKEEDLTKQKEMKENKS 1585 Query: 836 VVEKQLLEIEHENKELQKKNQILLEENQNLQI--SLSDMQQHYNALVEKANRTDLAESES 893 ++ + I + N+ ++K+ + L E +L+ SL + + + + KA ++ + E Sbjct: 1586 ELQNENERIRNLNEIIKKERETLKEMEAHLEKKKSLEETKANVIEMKTKAEPEEI-KKEK 1644 Query: 894 TKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKN 953 K + + E K + ++ I+ +++++E+ E + +I+ ++ + +K Sbjct: 1645 EKENEEEEEEEEEEKEDLEKMKSEIMTQRQQMEEERSELDNKIKQTDLERHDIENSKQKE 1704 Query: 954 IEYVTQLEAQ-----LQEYKNNIENLNMNVE-ELNKMNLELIDKHVQKQQTQSPDYTEQY 1007 + Q + + L+E K I + E E K E ++ V + + + E+ Sbjct: 1705 EDLTKQKKMEEERKSLEETKIKIIEMKTKTEPEKIKKEKEKEEEEVMRAKVEIKSQLERV 1764 Query: 1008 INEIN----KLN---ALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENM 1060 +EI+ KLN +++Q+ E++ + +I + S+ ++K+ Q + ++ Sbjct: 1765 RSEIDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDNKIKQTDLERHDI 1824 Query: 1061 EEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEP 1120 E + V K ++++K + ++E D++IK+ KET E ++ K + + S E Sbjct: 1825 ENSKEIVQKLMVENKAKLQNENERIKEMDEEIKKEKETLKEMEAHLRKEKEEMRSVIEET 1884 Query: 1121 MSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKI-IQLE 1179 +++ ++ ++ + +R +L++ KL E++E +I Q E Sbjct: 1885 QRRQKEDLEKMSTDVN--------KQNQDLMNQRDLLKQ---KLMVEVEEQKHEIQFQKE 1933 Query: 1180 TLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELW 1239 L+ E Q+ + Q KS+L+ N E D L+ E ++ + + + EI + Sbjct: 1934 ELDIE-RQKIADEQDLLIQNKSELQNEN-EQDLLIQNKIEQQNE-NERIKEMDEEIKK-E 1989 Query: 1240 KQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKL 1299 ++ L + E + QK + E+ S E + D + T E+ I+ E TS+ + Sbjct: 1990 RETLKEMEVNLQKEKEEIE---SVIEETQRRKEDLEKGETVEKHTDII-KEYTTSIPKEE 2045 Query: 1300 QDKEEHLRN----LQEKYADVINQIEILRSEIED 1329 + E RN LQ++ V +E ++++ E+ Sbjct: 2046 YEIERAARNRETILQKREEIVKRHMEEIQNQREE 2079 Score = 93.9 bits (223), Expect = 3e-17 Identities = 147/739 (19%), Positives = 322/739 (43%), Gaps = 54/739 (7%) Query: 843 EIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRD 902 E E +++ ++KNQ+L E + +L+D+ + + L E + + ++R Sbjct: 5 EREDLSEDAKRKNQVLDEMKVANESTLADILRERSNLQEMRENISKQTEDVENKKEKIRL 64 Query: 903 LESNLKRI---THEHQTLIVQKKKEIEDLE---IEFNTQIESAIRDKKVL-NEKYE-KNI 954 E LK++ H+ Q+ ++K IE I + ES D++ NEK E K + Sbjct: 65 REEKLKQLQAEIHKQQSETEKEKSNIERERAAIINLDRDAESLKLDREAFENEKEELKQM 124 Query: 955 EYVTQLEAQLQEYKNNIENLNMNVEELNKMNLEL------IDKH---VQKQQTQSPDYTE 1005 + + EA++ + K+ E + +EL+++ E+ ++K + K + + + TE Sbjct: 125 KTELEREAEIHDIKHQEEQMKQKQDELDQLKTEIQNLQQELEKEKEIIMKDRNKDKEETE 184 Query: 1006 QYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQ 1065 + E+ K D+ +L++ + ++ ++ D +SK + E ++ E Q Sbjct: 185 EQKQEMEKEK---HDFDQSRKSLDEDLKMMKLQ-KQVLEDEKSKKIK-----EEIQNERQ 235 Query: 1066 RVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDA 1125 + K K+ E+L ++ + + E+K + +I + E + E +S Sbjct: 236 NLEKMTEALKEEREDLAEETKKNNQVLDEMKVANESTLADILR-EKSNLEEMRENISKQT 294 Query: 1126 NNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTEL 1185 +V+ L+ + E Q+R + +E K+N E E I +E L + Sbjct: 295 EDVENKKENLRLREDELRQLQAEIHKQQREIEKE---KINIE-SERAAIIKDVEDLQHKN 350 Query: 1186 TGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQ--HL 1243 ++ +++I +K + +Q ND ++ T+ R + ++ + E+ K+ ++ Sbjct: 351 LQQELEKEKEI-IMKDRNKQQTNMND-IMETMKNERKQLDKDKEEMEEQKQEMEKERDNM 408 Query: 1244 AQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTM-EQVTSLQNKLQDK 1302 Q + + ++++Q FE + + L+ ++ + E ++I + E+ + + +L+ Sbjct: 409 DQSRKSLDEDQKKMKLQKQMFEEE-KNKLEQMKIELEREADEISKIKEETQNKRQRLEKM 467 Query: 1303 EEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQM 1362 E L NLQ + + +E +R I K + L+TE Q + Sbjct: 468 TEELINLQREK----SILEEMRENISKLK-EYIDNEKEKSKLREDELKKLQTEVQKQQSK 522 Query: 1363 QEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHE 1422 + NI E A + + + D E ++ E+ + EL ++ T + Sbjct: 523 IDMEKTNIESERAAMIREK---QNMMTELKKKSEDVEIQMKEILTEKELLHNDRKLLTRD 579 Query: 1423 YTITLTQRNDEFENVRQQL-VEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKE-S 1480 L Q+ + E ++L ++ E EDL +KE+ LA ++ + + E + +E Sbjct: 580 VE-NLQQKLIDLERDSKRLKLDREAFKEDLEKQKENTLAEIQKEREDVEKMNENITREMH 638 Query: 1481 EIERVKLIEELNVKITESVSLNKQVAELNKALEEE---VAKTNEMQTALENQEIEIVTLN 1537 EI+ + E++N K E L ++ L + LE+E + K +M +++QE ++ Sbjct: 639 EIKHQE--EQMNQKQDELDQLKTEIQNLQQELEKEKEIIMKDRKMH-EIKHQEEQMNQKQ 695 Query: 1538 DEITNLQNMVRASSSKIQK 1556 DE+ L+ ++ +++K Sbjct: 696 DELDQLKTEIQNLQQELEK 714 Score = 90.2 bits (214), Expect = 4e-16 Identities = 140/719 (19%), Positives = 322/719 (44%), Gaps = 59/719 (8%) Query: 212 EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271 ++ K+ + + + + + EK+ ++K DV + ++ NK +E ++E+ + Sbjct: 1429 DEEKKLLEQKANEILRQRDDLEKEKEDMMKKWNKLDVLQNEMQNENKAMEEIKYELDGKR 1488 Query: 272 SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTE----LTKK 327 +++ +E +Q +Q + + K+E++ + I N+ E L ++ Sbjct: 1489 NEINKE-QQRLEKEELDIERQKIADEQDL--LIQNKSELQNENE-RIRNINEQRDLLEQE 1544 Query: 328 IELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGR--NTASKMKSP 385 E + H Q++Q E + +++ E K+ + ++ R N +K Sbjct: 1545 KEDINHEWTQLQQRIDEFDAQVSKQKEEDLTKQKEMKENKSELQNENERIRNLNEIIKKE 1604 Query: 386 WSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLV---DKEYVISEKDTXXXXXXXXX 442 L + + K + + + +EM ++ +++ +KE E++ Sbjct: 1605 RETLKEMEAHLEKKKSLEETKANVIEMKTKAEPEEIKKEKEKENEEEEEEEEEEKEDLEK 1664 Query: 443 XGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQL-KQELNDE----IKDVN 497 + + + Q+E ++ + D+ + +E L KQ+ +E +++ Sbjct: 1665 MKSEIMTQRQQMEEERSELDNKIKQTDLERHDIENSKQKEEDLTKQKKMEEERKSLEETK 1724 Query: 498 VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSK-VSDSNKE 556 +K + K K+ E+I + E + + +++ K K +L++++ ID+ K ++D K Sbjct: 1725 IKIIEMKTKTEPEKIKK---EKEKEEEEVMRAKVEIKSQLERVRSEIDHEQKKLNDDKKM 1781 Query: 557 IVRLTEELHHLSQKVA----ELEEEKGNLQLHLVDYDSGRM-IESD---VYKKMIE---- 604 I + E+L + ++ ++EEE+ L + D R IE+ V K M+E Sbjct: 1782 IEQEKEDLEKMKSEIMKQRQQMEEERSELDNKIKQTDLERHDIENSKEIVQKLMVENKAK 1841 Query: 605 MENLAETRLKAISLLESQKFDLVQ-ELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVH 663 ++N E + ++ +K L + E H+ ++K +E+ + + + Q + + V+ Sbjct: 1842 LQNENERIKEMDEEIKKEKETLKEMEAHLRKEK-EEMRSVIEETQRRQKEDLEKMSTDVN 1900 Query: 664 LEEQ--IDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLT 721 + Q ++ K++L + +E K ++ ++L+ +++ I ++ IQ +L Sbjct: 1901 KQNQDLMNQRDLLKQKLMVEVEE---QKHEIQFQKEELDIERQKIADEQDLLIQNKSELQ 1957 Query: 722 DKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRI-CR 780 ++ E+ +LL + E+Q++ + +D +I++ ++ +E L K K I Sbjct: 1958 NENEQ-------DLLIQNKIEQQNENERIKEMDEEIKKERETLKEMEVNLQKEKEEIESV 2010 Query: 781 LEESIAVMED--RRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVE 838 +EE+ ED + ++E+ D + Y K EY I E NR +L + +V+ Sbjct: 2011 IEETQRRKEDLEKGETVEKHTDIIKEYTTSIPK--EEYEI-ERAARNRETILQKREEIVK 2067 Query: 839 KQLLEIEHENKELQKK-NQILLEENQN---LQISLSDMQQHYNALVEKANRTDL-AESE 892 + + EI+++ +ELQKK Q L +E +N L I ++ + L+E+ R + AE+E Sbjct: 2068 RHMEEIQNQREELQKKMMQDLQKERENVNALVIQHQKEREQRDILIEENKRKEKHAEAE 2126 Score = 83.8 bits (198), Expect = 4e-14 Identities = 171/861 (19%), Positives = 360/861 (41%), Gaps = 66/861 (7%) Query: 152 KEKDNALSVLQVKMKIMETTILDL-QEKINEKDQIIEAKN----------KATTXXXXXX 200 KEK S LQ + + +ET+I L EK K+QI + K + Sbjct: 1264 KEKGKLRSELQRQREDLETSIQKLTHEKREIKNQIEQEKKDLQNMKSNLERQLESLRHEK 1323 Query: 201 XXXXXXXXXXXEDTKQQMTKMQENFIAM---EAEWKDEKQRLL---KDIESKDVRISSLE 254 ++ KQ+ ++++ + + + E ++E+ L+ +E +I + E Sbjct: 1324 ANVEGLLEKEKQELKQEKKELEDQMMDLTREKQETEEERNNLMALKNQLEDLKEQIQNNE 1383 Query: 255 EANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKG 314 A LLE R +I + +L ++ + ++K+S++ EEK +E+K Sbjct: 1384 NAKHLLEQERKDIDKQKQELQKQADDLDMRMIAHRENVE-MSKRSLD---EEKKLLEQKA 1439 Query: 315 SLEIANMTELTK-KIELLEHLN-CQIRQTNKELENK-LATMGTESKAVSSPSKKGSPLIS 371 + + +L K K ++++ N + Q + ENK + + E + K + Sbjct: 1440 NEILRQRDDLEKEKEDMMKKWNKLDVLQNEMQNENKAMEEIKYELDGKRNEINKEQQRLE 1499 Query: 372 RKSGRNTASKMKSPWSQL--SSETLNQDTDKKINKNEIAKL-EMVIQSLNKDLVDKEYVI 428 ++ K+ L + L + ++ N NE L E + +N + + I Sbjct: 1500 KEELDIERQKIADEQDLLIQNKSELQNENERIRNINEQRDLLEQEKEDINHEWTQLQQRI 1559 Query: 429 SEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIH--VGTNTEDVNEIAKVQEQLK 486 E D K + + + E Q E ++ + E + E+ E+ K Sbjct: 1560 DEFDAQVSKQKEEDLTKQKEMKENKSELQNENERIRNLNEIIKKERETLKEMEAHLEKKK 1619 Query: 487 --QELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANK-NMIKVKSNHKLKLKQMQKT 543 +E + ++ K E++K +E+ + +E + K ++ K+KS + +QM++ Sbjct: 1620 SLEETKANVIEMKTKAEPEEIKKEKEKENEEEEEEEEEEKEDLEKMKSEIMTQRQQMEEE 1679 Query: 544 ---IDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQ---LHLVDYDSGRMIESD 597 +DN K +D + + +++ K ++EEE+ +L+ + +++ + E Sbjct: 1680 RSELDNKIKQTDLERHDIENSKQKEEDLTKQKKMEEERKSLEETKIKIIEMKTKTEPEKI 1739 Query: 598 VYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCS 657 +K E E + +++ S LE + ++ E L +E + D+ +++S+ + Sbjct: 1740 KKEKEKEEEEVMRAKVEIKSQLERVRSEIDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQ 1799 Query: 658 EIKSVHLEEQIDALSASKKELALV---IENLKLDKEQLYGTIK-DLENDKEDIMNKLQNY 713 + +EE+ L K+ L IEN K ++L K L+N+ E I + Sbjct: 1800 RQQ---MEEERSELDNKIKQTDLERHDIENSKEIVQKLMVENKAKLQNENERIKEMDEEI 1856 Query: 714 IQENMDLTD-----KLEKMSAEKISELLAKINHEEQSKIQTQFGIDAK--IQERDLYIEN 766 +E L + + EK + E + E+ K+ T + + +RDL + Sbjct: 1857 KKEKETLKEMEAHLRKEKEEMRSVIEETQRRQKEDLEKMSTDVNKQNQDLMNQRDLLKQK 1916 Query: 767 IESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELV-N 825 + E+ + K I +E + + ++ AD+ +Q K + +E ++D L+ N Sbjct: 1917 LMVEVEEQKHEIQFQKEELDIER------QKIADEQDLLIQNKSELQNEN--EQDLLIQN 1968 Query: 826 RLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANR 885 ++ +++R+ E EI+ E + L++ L +E + ++ + + Q+ L EK Sbjct: 1969 KIEQQNENERIKEMDE-EIKKERETLKEMEVNLQKEKEEIESVIEETQRRKEDL-EKGET 2026 Query: 886 TDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKV 945 + +Y T + E ++R +T I+QK++EI +E Q + KK+ Sbjct: 2027 VEKHTDIIKEYTTSIPKEEYEIERAARNRET-ILQKREEIVKRHME-EIQNQREELQKKM 2084 Query: 946 LNEKYEKNIEYVTQLEAQLQE 966 + + +K E V L Q Q+ Sbjct: 2085 MQD-LQKERENVNALVIQHQK 2104 >UniRef50_A2FQ07 Cluster: Viral A-type inclusion protein, putative; n=1; Trichomonas vaginalis G3|Rep: Viral A-type inclusion protein, putative - Trichomonas vaginalis G3 Length = 2366 Score = 184 bits (447), Expect = 2e-44 Identities = 308/1509 (20%), Positives = 627/1509 (41%), Gaps = 152/1509 (10%) Query: 140 QLGDVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXX 199 ++ D+ +++K+N L + K +E + + N+ ++ KNKA + Sbjct: 905 KINDLMAQIKALQQKNNELDK---ENKELEAAKEASENENNDLKNDLQTKNKALSKAERD 961 Query: 200 XXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKL 259 E K+++ +++ ++A ++ L K+ + +++ ++ K Sbjct: 962 NDKLQNANKALDE-AKEKIKALEDEVSDLKALVSEKDGDLQKEKRENERLVANKDQLTKN 1020 Query: 260 LEAARFEI---SLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSL 316 E ++ + E KL +++ L K + E E+ E + K Sbjct: 1021 NEELYDQLKNETTEKIKLDGQVKNAERDLAKANATNEELTKSN-EHLQEQNDEKDAKIKE 1079 Query: 317 EIANMTELTKKIELLEHLNCQI---RQTNKELENKLATMGTESKAVSSPSKKGSPLISRK 373 A + EL KK+ L L +I ++TN EL+N + + KA K + L + Sbjct: 1080 LQAKLNELEKKLSELPGLQDEIAKQKETNNELQNNVNDL---EKAGKDKDNKINELQKKA 1136 Query: 374 SG-RNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVD----KEYVI 428 + NT ++ ++L E +D D NKN LE I+ L K + D K + Sbjct: 1137 NELENTKKDLEDVTNEL--ENTQKDLDNSNNKNR--DLEKQIKDLKKQIEDLNREKNDLK 1192 Query: 429 SEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQE 488 + DT +D ++ L+ + + + N + E+A + +L + Sbjct: 1193 DQLDTSKLAGDELSK-RDEVLDNLRKQIAELAAKNKDLENKANDNNAEELAAKEAEL-EN 1250 Query: 489 LNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQ-KTIDNF 547 +N +++ K+L E+ EE N+ + +N + N +LK +Q K ++ Sbjct: 1251 INKQLEQTK-KELAER---DEELKNAKNENLAKEKENQKLNRENERLKFEQQDLKDLEEE 1306 Query: 548 SK-VSDSN----KEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYD------SGRMIES 596 +K + D N ++ L +L + L+ LQ ++ D D S I+ Sbjct: 1307 NKNLDDENAALKSKVNALENDLQKAKRDADRLKLNNDQLQTNIDDLDNKLKEESAEKIKL 1366 Query: 597 DVYKKMIEME-----NLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQ 651 D K + E E KA L+ Q D +L +Q K +E++ K D ++Q Sbjct: 1367 DAQAKAADRELQSAKAATEEEKKANDQLQGQIKDKDNKLKEMQAKLNEMQKKANDADRIQ 1426 Query: 652 SDQVCSEIKSV--HLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNK 709 + + + +KS + + EL + + QL T ++LE+ + D+ N+ Sbjct: 1427 N--LANSLKSQLDDANKSNNEKDNQLNELQKKLNEAQKKANQLEPTKQELEDARNDL-NE 1483 Query: 710 LQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQS---KIQTQFGIDAKIQERDLYIEN 766 Q + + + LEK + + + + +N+E+Q+ + T D ++ +RD + N Sbjct: 1484 KQKELDASNNKNRDLEKQIKD-LKKQIGDLNNEKQALKDDLDTSKLADDELSKRDEVLGN 1542 Query: 767 IESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNR 826 ++ +L+ ++ LE V D L K +L + + ++ + EDEL N Sbjct: 1543 LKKQLADQLAKNKELEAK--VKGDNGDELAAKDAELDALKDQLEQVKKDLAETEDELKNA 1600 Query: 827 LAVLMDHDRVVEKQLLEIEH---ENKELQKKNQILLE---ENQNLQISLSDMQQHYNALV 880 D+ ++K ++EH +L+K N+ + EN L+ L++ + Sbjct: 1601 RNESSAKDKEIQKLARDLEHLKDAEDDLEKANEEIKNRDAENNELKGQLANKENELQKSK 1660 Query: 881 EKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAI 940 ++ +R L++ + +K+ DL + L T ++ L Q +++LE T Sbjct: 1661 QENDRLQLSKDQLSKHND---DLNNQLTAATTDNIKLDAQ----VKELERRLGTN----- 1708 Query: 941 RDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQS 1000 N E+ + + QL+++ + N I++L+ +++N + + D +QQ Sbjct: 1709 ------NAAQEQQAQTIEQLKSEAADKDNKIKDLH---DQINNLQKKANDADNLQQQL-- 1757 Query: 1001 PDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENM 1060 DY + ++E NK N KD ++ L +K N +Q ++L +LE+ Sbjct: 1758 -DYAKSQLDEANKSN---NDKDNQLNELQKKFNESQKK--------ANQLEPTKQELEDS 1805 Query: 1061 EEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIP---KTEGMI---- 1113 ++ K+L +S N +L+ ++E QI++LK+ K + + K + +I Sbjct: 1806 RNDLNEKQKELDESNNKNRDLEKQIKELKKQIEDLKKQKDDLQEQLDNNVKADDVIDKLR 1865 Query: 1114 --ISSTIEPMSD-DANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQE 1170 I+ + + + +A N D ++ + +F Q + L E+ +L Sbjct: 1866 KQIAELLAKVKELEAKNKDNTGDELAVKDAEIE-SLKNQFEQAKKDLDEKELELKQTSDN 1924 Query: 1171 CYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQ 1230 +K +L+ N EL V+QE + Q + ++L+ EN L + +A + + + Sbjct: 1925 LSSKDKELQKANRELERLQDVDQE-LAQANEENKKLDAENGELKTQLANTENELQKSKQD 1983 Query: 1231 RGFEIAELWKQHLAQREADFQKT---EHELRVQLSAFESKYEQLLDSVQSSTQEETNKIV 1287 E + L + D K E ++L+ + ++ L + ++ ++ I Sbjct: 1984 N--ERLQSSNDQLTKNTDDLNKKLTDETTDNIKLNGLIQELQRRLANNDAAIAQQAESID 2041 Query: 1288 TM-EQVTSLQNKLQDKEEHLRNLQEKYADVIN---QIEILRSEIEDEKVAFXXXXXXXXX 1343 + EQ NK++D + + NLQ+K D N Q++ +S++++ + Sbjct: 2042 KLNEQAADKDNKIKDLHDQINNLQKKANDADNLQQQLDYAKSQLDEANKSNNDKDNQLNE 2101 Query: 1344 XXXXXXXDLRTENQ--SYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAK 1401 + NQ KQ E S ++NE+ +L +S+ + D E + Sbjct: 2102 LQKKFNESQKKANQLEPTKQELEDSRNDLNEKQKELDESNN-----------KNRDLEKQ 2150 Query: 1402 VLELTHQLELKDSE---IYQKTHEYTIT---LTQRNDEFENVRQQLVEYEKRIEDLTYEK 1455 + EL Q+ DSE + K + + +++R++ +N+R+Q+ E + +DL Sbjct: 2151 IKELKKQIGNLDSEKQALQDKLDDIKLADDAISKRDEVLDNLRKQIAELAAKNKDLEN-- 2208 Query: 1456 ESELAILRLKMHENANHYETMQKESEIERV-KLIEELNVKITESVSLNKQVAELNKALEE 1514 K ++N N E KE+E+E + K +E+ ++ E K N A E+ Sbjct: 2209 ---------KANDN-NAEELAAKEAELENINKQLEQTKKELAERDEELKNAKNENLAKEK 2258 Query: 1515 EVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDE-QLD 1573 E K N L+ ++ ++ L +E NL + A SK+ + K+ D +L+ Sbjct: 2259 ENQKLNRENERLKFEQQDLKDLEEENKNLDDENAALKSKVNALENDLQKAKRDADRLKLN 2318 Query: 1574 NTMNKELLD 1582 N + +D Sbjct: 2319 NDQLQTNID 2327 Score = 171 bits (415), Expect = 2e-40 Identities = 301/1479 (20%), Positives = 638/1479 (43%), Gaps = 148/1479 (10%) Query: 147 LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXX 206 LS T ++ DN K+K +++ + DL++K N+ D ++ K Sbjct: 724 LSKTNEQLDNFNKDKDNKIKELQSKVNDLEKKSNQLDD-ANSRIKELEDELSESEASKDD 782 Query: 207 XXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAAR-- 264 D +++ +Q+ M+ + D +Q K + + + + +K L+AA Sbjct: 783 ISNKLNDLQKKSNDLQKKSDQMKKDLDDSQQENAKKQKENEDLQNQQRDLDKKLKAAEKR 842 Query: 265 -FEISLEHSKLAQELEQ-XXXXXXXXXXXXXXLAKQS--IEPSCEEKTEIEEKGS--LEI 318 E+ E+S L + L+ +A+Q+ I+ E + KG E+ Sbjct: 843 IQELLGENSDLHETLDNINTSSMQQGDEMNKVIAEQAAKIKALQEAVNNSQPKGEDPNEL 902 Query: 319 AN-MTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRN 377 + + +L +I+ L+ N ++ + NKELE E+ + + + + +S+ N Sbjct: 903 HDKINDLMAQIKALQQKNNELDKENKELEAAKEASENENNDLKNDLQTKNKALSKAERDN 962 Query: 378 TASKMKSPWSQLSSETLNQDTDK-KINKNEIAKLEMVIQ----SLNKDLVDKEYVISEKD 432 K+ Q +++ L++ +K K ++E++ L+ ++ L K+ + E +++ KD Sbjct: 963 --DKL-----QNANKALDEAKEKIKALEDEVSDLKALVSEKDGDLQKEKRENERLVANKD 1015 Query: 433 TXXXXXXXXXXG-KDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELND 491 K+ +++L+ Q L E E+ K E L QE ND Sbjct: 1016 QLTKNNEELYDQLKNETTEKIKLDGQVKNAERDLAKANATNE---ELTKSNEHL-QEQND 1071 Query: 492 EIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKV- 550 E KD +K+L KL E++++ E+ + K K + ++Q +++ K Sbjct: 1072 E-KDAKIKELQAKLNELEKKLS----ELPGLQDEIAKQKETN----NELQNNVNDLEKAG 1122 Query: 551 SDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAE 610 D + +I L ++ + L +LE+ L+ D D+ D Sbjct: 1123 KDKDNKINELQKKANELENTKKDLEDVTNELENTQKDLDNSNNKNRD------------- 1169 Query: 611 TRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSV-HLEEQID 669 LE Q DL +++ L ++ ++++D+L D S+L D++ + + +L +QI Sbjct: 1170 --------LEKQIKDLKKQIEDLNREKNDLKDQL-DTSKLAGDELSKRDEVLDNLRKQIA 1220 Query: 670 ALSASKKELALVIENLKLDK--EQLYGTIKDLENDKEDIMNKLQNYIQENMDLTD-KLEK 726 L+A K+L EN D E+L +LEN + + + + + +L + K E Sbjct: 1221 ELAAKNKDL----ENKANDNNAEELAAKEAELENINKQLEQTKKELAERDEELKNAKNEN 1276 Query: 727 MSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIA 786 ++ EK ++ L + N E+ K + Q D K E + +N++ E + KS++ LE + Sbjct: 1277 LAKEKENQKLNREN--ERLKFEQQ---DLKDLEEE--NKNLDDENAALKSKVNALENDLQ 1329 Query: 787 VMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEH 846 + L+ DQL + + + E + ++ +L + + +++L + Sbjct: 1330 KAKRDADRLKLNNDQLQTNIDDLDNKLKEESAEKIKLDAQA-------KAADRELQSAKA 1382 Query: 847 ENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDL-ES 905 +E +K N L + ++ L +MQ N + +KAN D ++ + ++QL D +S Sbjct: 1383 ATEEEKKANDQLQGQIKDKDNKLKEMQAKLNEMQKKANDADRIQNLANSLKSQLDDANKS 1442 Query: 906 NLKRIT--HEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQ 963 N ++ +E Q + + +K+ LE ++E A D LNEK +K ++ Sbjct: 1443 NNEKDNQLNELQKKLNEAQKKANQLE-PTKQELEDARND---LNEK-QKELDASNNKNRD 1497 Query: 964 LQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDE 1023 L++ I++L + +LN +K K + + +++ +++ LK++ Sbjct: 1498 LEK---QIKDLKKQIGDLNN------EKQALKDDLDTSKLADDELSKRDEVLGNLKKQLA 1548 Query: 1024 EIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQI 1083 + +A N+++ A+V D +LA +L+ +++++++V K L +++ +EL+ Sbjct: 1549 DQLAKNKEL-EAKVK-----GDNGDELAAKDAELDALKDQLEQVKKDLAETE---DELKN 1599 Query: 1084 LVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLK 1143 E + KE+++ E ++ E + + E + DA N + K Sbjct: 1600 ARNESSAKDKEIQKLARDLE-HLKDAEDDLEKANEEIKNRDAENNELKGQLANKENELQK 1658 Query: 1144 VQEEEEFIQ-ERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSK 1202 ++E + +Q + L + + LN +L T I+L+ EL N Q Sbjct: 1659 SKQENDRLQLSKDQLSKHNDDLNNQLTAATTDNIKLDAQVKELERRLGTNNAAQEQQAQT 1718 Query: 1203 LEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQ-HLAQREAD-FQKTEHELRVQ 1260 +EQL +E + + + +L I++ + ++ + L +Q A+ + D K+ ++ Q Sbjct: 1719 IEQLKSEAADKDNKIKDLHDQINN-LQKKANDADNLQQQLDYAKSQLDEANKSNNDKDNQ 1777 Query: 1261 LSAFESKYEQLLDSVQSSTQEETNKI-VTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQ 1319 L+ + K+ + +Q++ N++ T +++ +N L +K++ L K D+ Q Sbjct: 1778 LNELQKKFNE--------SQKKANQLEPTKQELEDSRNDLNEKQKELDESNNKNRDLEKQ 1829 Query: 1320 IEILRSEIED-EKVAFXXXXXXXXXXXXXXXXD-LRTE-NQSYKQMQEQSILNINEENAQ 1376 I+ L+ +IED +K D LR + + +++E N + + Sbjct: 1830 IKELKKQIEDLKKQKDDLQEQLDNNVKADDVIDKLRKQIAELLAKVKELEAKNKDNTGDE 1889 Query: 1377 LKKSSXXXXXXXXXXXXRVNDAEAKVLEL---THQLELKDSEIYQKTHEYTITLTQRNDE 1433 L D + K LEL + L KD E+ + E +R + Sbjct: 1890 LAVKDAEIESLKNQFEQAKKDLDEKELELKQTSDNLSSKDKELQKANRE-----LERLQD 1944 Query: 1434 FENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNV 1493 + Q E K+++ E +++LA ++ ++ E +Q ++ + K ++LN Sbjct: 1945 VDQELAQANEENKKLDAENGELKTQLANTENELQKSKQDNERLQSSND-QLTKNTDDLNK 2003 Query: 1494 KI----TESVSLNKQVAELNK-------ALEEEVAKTNEMQTALENQEIEIVTLNDEITN 1542 K+ T+++ LN + EL + A+ ++ +++ +++ +I L+D+I N Sbjct: 2004 KLTDETTDNIKLNGLIQELQRRLANNDAAIAQQAESIDKLNEQAADKDNKIKDLHDQINN 2063 Query: 1543 LQNMVRASSSKIQKHVSFAS---DTKQGRDEQLDNTMNK 1578 LQ + +Q+ + +A D + DN +N+ Sbjct: 2064 LQKKAN-DADNLQQQLDYAKSQLDEANKSNNDKDNQLNE 2101 Score = 161 bits (391), Expect = 1e-37 Identities = 290/1514 (19%), Positives = 636/1514 (42%), Gaps = 122/1514 (8%) Query: 149 NTIKEKDNALSVLQVKMKIMETTILDLQEKI-NEKDQI----IEAKNKATTXXXXXXXXX 203 +T+K+KD ++ L K+K I DLQ ++ N K+++ + ++K Sbjct: 456 DTLKDKDAKINDLNNKLKDNNKAINDLQNQLDNAKNELENLRKQLESKQNELKDAEKKLN 515 Query: 204 XXXXXXXXEDTKQQMTKMQENFIAMEAEWK-DEKQRLLKDIESKDVRISSLEEANKL-LE 261 +T+ + + Q + I + E + DE L K + + E NK E Sbjct: 516 DAKRKNKDLETENEALQDQVDSINTDKEQQGDELANLRKMLSDQTANFKKNNEDNKKENE 575 Query: 262 AARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANM 321 + E+ L +++Q A+ ++ ++ + + + Sbjct: 576 KELAKKEAENRALQNQIDQLKKLLQGSEEDLKN-AQNELQAKDKDLAKAQRENERLANAQ 634 Query: 322 TELTKKIELLEHLNCQIRQTNKEL---ENKLATMGTES---KAVSSPSKKGSPLISRKSG 375 +L +E ++L+ ++ +L EN+ E+ KA++ +K S +++K Sbjct: 635 NQLQSNLEEKKNLDDELTDLKSKLAAIENEKQKAERENERLKAMNDQLEKTSDDLNKKLT 694 Query: 376 RNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXX 435 T ++K SQ + T K ++ E++K + + NKD +K + K Sbjct: 695 DETRERIKLD-SQAKAADRELQTAKAASE-ELSKTNEQLDNFNKDKDNKIKELQSKVNDL 752 Query: 436 XXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTN--TEDVNEIAKVQEQLKQELNDEI 493 ++ I +L+ E + I N + N++ K +Q+K++L+D Sbjct: 753 EKKSNQLDDANSRIKELEDELSESEASKDDISNKLNDLQKKSNDLQKKSDQMKKDLDDSQ 812 Query: 494 KDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVS-- 551 ++ N K E + + Q L+ ++ AA K + ++ + + +T+DN + S Sbjct: 813 QE-NAKKQKEN-EDLQNQQRDLDKKLKAAEKRIQELLGEN----SDLHETLDNINTSSMQ 866 Query: 552 ---DSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIE-SDVYKKMIEMEN 607 + NK I ++ L Q+ + KG L D + M + + +K E++ Sbjct: 867 QGDEMNKVIAEQAAKIKAL-QEAVNNSQPKGEDPNELHDKINDLMAQIKALQQKNNELDK 925 Query: 608 LAETRLKAISLLESQKFDLVQELHILQQKYDEVE---DKLADISQLQSDQVCSEIKSVHL 664 + A E++ DL +L + + E DKL + ++ D+ +IK+ L Sbjct: 926 ENKELEAAKEASENENNDLKNDLQTKNKALSKAERDNDKLQNANK-ALDEAKEKIKA--L 982 Query: 665 EEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKL 724 E+++ L A E ++ K + E+L L + E++ ++L+N E + L ++ Sbjct: 983 EDEVSDLKALVSEKDGDLQKEKRENERLVANKDQLTKNNEELYDQLKNETTEKIKLDGQV 1042 Query: 725 EKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIE---SELSKYKSRICRL 781 + + LAK N + ++ + + E+D I+ ++ +EL K S + L Sbjct: 1043 KNAERD-----LAKANATNEELTKSNEHLQEQNDEKDAKIKELQAKLNELEKKLSELPGL 1097 Query: 782 EESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQL 841 ++ IA ++ L+ + L ++K +E + +EL N L D +E Sbjct: 1098 QDEIAKQKETNNELQNNVNDLEKAGKDKDNKINELQKKANELENTKKDLEDVTNELENTQ 1157 Query: 842 LEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLR 901 ++++ N KN+ L ++ ++L+ + D+ + N L ++ + + LA E +K L Sbjct: 1158 KDLDNSN----NKNRDLEKQIKDLKKQIEDLNREKNDLKDQLDTSKLAGDELSKRDEVLD 1213 Query: 902 DLESNLKRITHEHQTL-----------IVQKKKEIEDLEIEF-NTQIESAIRDKKVLNEK 949 +L + + +++ L + K+ E+E++ + T+ E A RD+++ N K Sbjct: 1214 NLRKQIAELAAKNKDLENKANDNNAEELAAKEAELENINKQLEQTKKELAERDEELKNAK 1273 Query: 950 YEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYIN 1009 E L + + K N EN + E+ + +LE +K++ + N Sbjct: 1274 NE-------NLAKEKENQKLNRENERLKFEQQDLKDLEEENKNLDDENAALKSKVNALEN 1326 Query: 1010 EINKLNALLKQKDEEIIALNQKINNAQVSYM-SMVSDYESKLAQFTTKLENMEEEMQRVS 1068 ++ K ++D + + LN + + + + + ++ + + + + E+Q Sbjct: 1327 DLQK-----AKRDADRLKLNNDQLQTNIDDLDNKLKEESAEKIKLDAQAKAADRELQSAK 1381 Query: 1069 KQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEG---MIISSTIEPMSDDA 1125 + K+ N++LQ ++++D+++KE+ + KL EM + ++++++ DDA Sbjct: 1382 AATEEEKKANDQLQGQIKDKDNKLKEM-QAKLN-EMQKKANDADRIQNLANSLKSQLDDA 1439 Query: 1126 NNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTEL 1185 N + K+ E ++ + +++ +L E ++ N +L Sbjct: 1440 NKSNNEKDNQLNELQK-KLNEAQKKANQLEPTKQELEDARNDLNEKQKELDASNNKNRDL 1498 Query: 1186 TGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQ---H 1242 ++QI LK ++ LN E L + + + +R + L KQ Sbjct: 1499 -------EKQIKDLKKQIGDLNNEKQALKDDL-DTSKLADDELSKRDEVLGNLKKQLADQ 1550 Query: 1243 LAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDK 1302 LA+ + K + + +L+A +++ + L D ++ Q + + T +++ + +N+ K Sbjct: 1551 LAKNKELEAKVKGDNGDELAAKDAELDALKDQLE---QVKKDLAETEDELKNARNESSAK 1607 Query: 1303 EEHLRNLQ---EKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSY 1359 ++ ++ L E D + +E EI++ + A + EN Sbjct: 1608 DKEIQKLARDLEHLKDAEDDLEKANEEIKN-RDAENNELKGQLANKENELQKSKQENDRL 1666 Query: 1360 KQMQEQSILNINEENAQLKKSSXXXXXXXX---------XXXXRVNDAEAKVLE-LTHQL 1409 + ++Q + ++ N QL ++ + +A+ +E L + Sbjct: 1667 QLSKDQLSKHNDDLNNQLTAATTDNIKLDAQVKELERRLGTNNAAQEQQAQTIEQLKSEA 1726 Query: 1410 ELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDL---TYEKESELAILRLKM 1466 KD++I + H+ L ++ ++ +N++QQL + ++++ +K+++L L+ K Sbjct: 1727 ADKDNKI-KDLHDQINNLQKKANDADNLQQQLDYAKSQLDEANKSNNDKDNQLNELQKKF 1785 Query: 1467 HEN---ANHYETMQKESEIERVKLIE---ELNVKITESVSLNKQVAELNKALEEEVAKTN 1520 +E+ AN E ++E E R L E EL+ ++ L KQ+ EL K +E+ + + Sbjct: 1786 NESQKKANQLEPTKQELEDSRNDLNEKQKELDESNNKNRDLEKQIKELKKQIEDLKKQKD 1845 Query: 1521 EMQTALENQ---EIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMN 1577 ++Q L+N + I L +I L V+ +K + + K E L N Sbjct: 1846 DLQEQLDNNVKADDVIDKLRKQIAELLAKVKELEAKNKDNTGDELAVKDAEIESLKNQFE 1905 Query: 1578 KELLDAVPRAELDL 1591 + D + EL+L Sbjct: 1906 QAKKD-LDEKELEL 1918 Score = 156 bits (379), Expect = 4e-36 Identities = 288/1462 (19%), Positives = 612/1462 (41%), Gaps = 126/1462 (8%) Query: 213 DTKQQMTKMQENFIAMEAEWKDEKQRLL-KDIESKDVRISSLEEANKLLEAARFEISLEH 271 D + Q+ ++Q+ AE + K ++ KD+E KD + S +E+ KLL+ + + Sbjct: 238 DLQDQLKRLQDQLDKQTAESQQLKSQIENKDLEGKD-KDSEIEKLKKLLKDKDNKSKNDL 296 Query: 272 SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELT-KKIEL 330 + ++ KQ + + + E E + ++ N E + KK +L Sbjct: 297 DEANANIDDLNKQLDQLRNALKDANKQ--KAAALDDLEKERDANSDLKNKLEDSDKKYKL 354 Query: 331 LEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLS 390 LE+ Q Q+ + +KLA M E + + P + + +N K +Q+ Sbjct: 355 LEN---QQNQSEEGARSKLAGMEVEFARLQKENNDLKPKLQDEVAKN-----KELQNQI- 405 Query: 391 SETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEY----VISEKDTXXXXXXXXXXGKD 446 E L D+ K +A+ + I+ ++ D + V + + KD Sbjct: 406 -ENLQDQIDEL--KRSLAEAQKQIKDKEAEIADVKNQLQGVEASQQQQNANAQDTLKDKD 462 Query: 447 TLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVK--DLIEK 504 I L + + + + + + + NE+ +++QL+ + N E+KD K D K Sbjct: 463 AKINDLNNKLKDNNKAINDLQNQLDNAK-NELENLRKQLESKQN-ELKDAEKKLNDAKRK 520 Query: 505 LKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEEL 564 K E + L D++D+ N + + K + NF K ++ NK+ E Sbjct: 521 NKDLETENEALQDQVDSINTDKEQQGDELANLRKMLSDQTANFKKNNEDNKK-----ENE 575 Query: 565 HHLSQKVAELEEEKGNL-QLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQK 623 L++K AE + + QL + S +++ + + ++LA+ + + L +Q Sbjct: 576 KELAKKEAENRALQNQIDQLKKLLQGSEEDLKNAQNELQAKDKDLAKAQRENERLANAQN 635 Query: 624 FDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIE 683 L L + DE+ D + ++ +++++ +E ++ L+ D L + +L + Sbjct: 636 -QLQSNLEEKKNLDDELTDLKSKLAAIENEKQKAERENERLKAMNDQLEKTSDDLNKKLT 694 Query: 684 NLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEE 743 + ++ +L K + + + + + N L D K KI EL +K+N E Sbjct: 695 DETRERIKLDSQAKAADRELQTAKAASEELSKTNEQL-DNFNKDKDNKIKELQSKVNDLE 753 Query: 744 QSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLG 803 + Q DA + ++L E ESE SK + + ++ + L++K+DQ+ Sbjct: 754 KKSNQLD---DANSRIKELEDELSESEASKDD-----ISNKLNDLQKKSNDLQKKSDQMK 805 Query: 804 SYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKK----NQILL 859 L + Q+ ++ + ++L N+ L + EK++ E+ EN +L + N + Sbjct: 806 KDLDDSQQENAKKQKENEDLQNQQRDLDKKLKAAEKRIQELLGENSDLHETLDNINTSSM 865 Query: 860 EENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIV 919 ++ + +++ AL E N + + + ++ DL + +K + ++ L Sbjct: 866 QQGDEMNKVIAEQAAKIKALQEAVNNSQPKGEDPNELHDKINDLMAQIKALQQKNNELDK 925 Query: 920 QKKK----------EIEDLEIEFNTQ---IESAIRDKKVL---NEKYEKNIEYVTQLEAQ 963 + K+ E DL+ + T+ + A RD L N+ ++ E + LE + Sbjct: 926 ENKELEAAKEASENENNDLKNDLQTKNKALSKAERDNDKLQNANKALDEAKEKIKALEDE 985 Query: 964 LQEYKNNIENLNMNVEELNKMNLELIDKHVQ--KQQTQSPDYTEQYINEINKLNALLKQK 1021 + + K + + ++++ + N L+ Q K + D + E KL+ +K Sbjct: 986 VSDLKALVSEKDGDLQKEKRENERLVANKDQLTKNNEELYDQLKNETTEKIKLDGQVKNA 1045 Query: 1022 DEEII---ALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEE---EMQRVSKQLLDSK 1075 + ++ A N+++ + + ++K+ + KL +E+ E+ + ++ K Sbjct: 1046 ERDLAKANATNEELTKSNEHLQEQNDEKDAKIKELQAKLNELEKKLSELPGLQDEIAKQK 1105 Query: 1076 QHNEELQILV-------REQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNV 1128 + N ELQ V +++D++I EL+ K E+ K + +++ +E D +N Sbjct: 1106 ETNNELQNNVNDLEKAGKDKDNKINELQ--KKANELENTKKDLEDVTNELENTQKDLDNS 1163 Query: 1129 DXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQ----------SAKLNTELQECYTKIIQL 1178 + LK ++ E+ +E++ L++Q +K + L +I +L Sbjct: 1164 NNKNRDLEKQIKDLK-KQIEDLNREKNDLKDQLDTSKLAGDELSKRDEVLDNLRKQIAEL 1222 Query: 1179 ETLNTELTGH-DVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAE 1237 N +L + N E++ +++LE +N + + +AE + +A ++ + E Sbjct: 1223 AAKNKDLENKANDNNAEELAAKEAELENINKQLEQTKKELAERDEELKNAKNENLAKEKE 1282 Query: 1238 LWK-----QHLAQREADFQKTEHE---LRVQLSAFESKYEQLLDSVQSSTQE----ETNK 1285 K + L + D + E E L + +A +SK L + +Q + ++ + N Sbjct: 1283 NQKLNRENERLKFEQQDLKDLEEENKNLDDENAALKSKVNALENDLQKAKRDADRLKLNN 1342 Query: 1286 IVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXX 1345 + L NKL+++ L + +++ ++ E+EK A Sbjct: 1343 DQLQTNIDDLDNKLKEESAEKIKLDAQAKAADRELQSAKAATEEEKKANDQLQGQIKDKD 1402 Query: 1346 XXXXXDLRTENQSYKQMQE-QSILNI-NEENAQL---KKSSXXXXXXXXXXXXRVNDAEA 1400 N+ K+ + I N+ N +QL KS+ ++N+A+ Sbjct: 1403 NKLKEMQAKLNEMQKKANDADRIQNLANSLKSQLDDANKSNNEKDNQLNELQKKLNEAQK 1462 Query: 1401 KV--LELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESE 1458 K LE T Q EL+D+ +E L N++ ++ +Q+ + +K+I DL EK++ Sbjct: 1463 KANQLEPTKQ-ELEDAR--NDLNEKQKELDASNNKNRDLEKQIKDLKKQIGDLNNEKQA- 1518 Query: 1459 LAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQV-AELNKALEEEVA 1517 L+ + + + + K E+ L ++L ++ ++ L +V + L + A Sbjct: 1519 ---LKDDLDTSKLADDELSKRDEV-LGNLKKQLADQLAKNKELEAKVKGDNGDELAAKDA 1574 Query: 1518 KTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQK------HVSFASDTKQGRDEQ 1571 + + ++ LE + ++ DE+ N +N A +IQK H+ A D + +E+ Sbjct: 1575 ELDALKDQLEQVKKDLAETEDELKNARNESSAKDKEIQKLARDLEHLKDAEDDLEKANEE 1634 Query: 1572 LDN--TMNKELLDAVPRAELDL 1591 + N N EL + E +L Sbjct: 1635 IKNRDAENNELKGQLANKENEL 1656 Score = 154 bits (374), Expect = 2e-35 Identities = 238/1141 (20%), Positives = 493/1141 (43%), Gaps = 122/1141 (10%) Query: 476 NEIAKVQEQLKQEL---NDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSN 532 N++ K+ + +Q + +E++++N K L E K ++ + LN +ID+ N Sbjct: 110 NQLTKLLQDREQAIARSGEEVENLNNK-LDEAEKKLKDTLNDLNPKIDSLTAE------N 162 Query: 533 HKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGR 592 LK KQ+Q+ + + + K + +LT Q ELE +K + D Sbjct: 163 ENLK-KQLQEQAPKLADMDNLTKSLKKLTRMQEKAKQ---ELENQKKQ------NADQEN 212 Query: 593 MIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQS 652 D+ E++N + E QK DL +L LQ D+++ + A+ QL+S Sbjct: 213 KYNQDIDALNKELQNQQQD-------FEKQKNDLQDQLKRLQ---DQLDKQTAESQQLKS 262 Query: 653 DQVCSEIKSVHLEEQIDAL--------SASKKELALV---IENLKLDKEQLYGTIKDLEN 701 +++ + +I+ L + SK +L I++L +QL +KD Sbjct: 263 QIENKDLEGKDKDSEIEKLKKLLKDKDNKSKNDLDEANANIDDLNKQLDQLRNALKDANK 322 Query: 702 DKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERD 761 K ++ L+ N DL +KLE ++K +LL E + Q++ G +K+ + Sbjct: 323 QKAAALDDLEKERDANSDLKNKLE--DSDKKYKLL------ENQQNQSEEGARSKLAGME 374 Query: 762 LYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQED 821 + ++ E + K +L++ +A ++ + +E DQ+ + +A + +E Sbjct: 375 VEFARLQKENNDLKP---KLQDEVAKNKELQNQIENLQDQIDELKRSLAEAQKQIKDKEA 431 Query: 822 ELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSD-MQQHYNALV 880 E+ + V+ QL +E ++ Q L++ L++ ++ + A+ Sbjct: 432 EIAD-----------VKNQLQGVEASQQQQNANAQDTLKDKDAKINDLNNKLKDNNKAIN 480 Query: 881 EKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAI 940 + N+ D A++E + QL ++ LK + +K K++E Q++S Sbjct: 481 DLQNQLDNAKNELENLRKQLESKQNELKD-AEKKLNDAKRKNKDLETENEALQDQVDSIN 539 Query: 941 RDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQS 1000 DK+ ++ + ++ A + KNN +N N +EL K E ++ +Q Q Q Sbjct: 540 TDKEQQGDELANLRKMLSDQTANFK--KNNEDNKKENEKELAKKEAE--NRALQNQIDQL 595 Query: 1001 PDYTEQYINEINKLNALLKQKDEEIIAL---NQKINNAQVSYMSMVSD---YESKLAQFT 1054 + ++ L+ KD+++ N+++ NAQ S + + + +L Sbjct: 596 KKLLQGSEEDLKNAQNELQAKDKDLAKAQRENERLANAQNQLQSNLEEKKNLDDELTDLK 655 Query: 1055 TKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKEL-KETKLTFEMNIPKTEGMI 1113 +KL +E E Q+ ++ K N++L+ + DD K+L ET+ +++ Sbjct: 656 SKLAAIENEKQKAERENERLKAMNDQLE---KTSDDLNKKLTDETRERIKLDSQAKAADR 712 Query: 1114 ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYT 1173 T + S++ + + K++E + + + Q N+ ++E Sbjct: 713 ELQTAKAASEELSKTNEQLDNFNKDKDN-KIKELQSKVNDLEKKSNQLDDANSRIKE--- 768 Query: 1174 KIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGF 1233 ++ E +E + D+ N ++N L+ K L ++D + + + S +A Q+ Sbjct: 769 --LEDELSESEASKDDISN--KLNDLQKKSNDLQKKSDQMKKDLDD--SQQENAKKQK-- 820 Query: 1234 EIAELWKQHLAQREADFQKTEHELRVQ-LSAFESKYEQLLDSVQSSTQ---EETNKIVTM 1289 E +L Q QR+ D + E R+Q L S + LD++ +S+ +E NK++ Sbjct: 821 ENEDLQNQ---QRDLDKKLKAAEKRIQELLGENSDLHETLDNINTSSMQQGDEMNKVIAE 877 Query: 1290 E--QVTSLQ---NKLQDKEEHLRNLQEKYADVINQIEILR---SEIEDEKVAFXXXXXXX 1341 + ++ +LQ N Q K E L +K D++ QI+ L+ +E++ E Sbjct: 878 QAAKIKALQEAVNNSQPKGEDPNELHDKINDLMAQIKALQQKNNELDKENKELEAAKEAS 937 Query: 1342 XXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAK 1401 DL+T+N++ + + N++ K+ V+D +A Sbjct: 938 ENENNDLKNDLQTKNKALSKAERD-----NDKLQNANKALDEAKEKIKALEDEVSDLKAL 992 Query: 1402 VLELTHQLELKDSEIYQKTHEYTITLTQRNDE-FENVRQQLVEYEKRIEDLTYEKESELA 1460 V E L+ K+ ++ LT+ N+E ++ ++ + E + +++ E +LA Sbjct: 993 VSEKDGDLQ-KEKRENERLVANKDQLTKNNEELYDQLKNETTE-KIKLDGQVKNAERDLA 1050 Query: 1461 ILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTN 1520 E E +Q++++ E+ I+EL K+ E L K+++EL L++E+AK Sbjct: 1051 KANATNEELTKSNEHLQEQND-EKDAKIKELQAKLNE---LEKKLSEL-PGLQDEIAKQK 1105 Query: 1521 EMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQ---KHVSFASDTKQGRDEQLDNTMN 1577 E L+N ++ + N N ++ +++++ K + ++ + + LDN+ N Sbjct: 1106 ETNNELQNNVNDLEKAGKDKDNKINELQKKANELENTKKDLEDVTNELENTQKDLDNSNN 1165 Query: 1578 K 1578 K Sbjct: 1166 K 1166 Score = 149 bits (360), Expect = 8e-34 Identities = 261/1221 (21%), Positives = 518/1221 (42%), Gaps = 110/1221 (9%) Query: 446 DTLIAQLQ-LEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEK 504 D+L A+ + L+ Q + P L + T+ + ++ ++QE+ KQEL ++ K ++ Sbjct: 156 DSLTAENENLKKQLQEQAPKLADMDNLTKSLKKLTRMQEKAKQELENQ-----KKQNADQ 210 Query: 505 LKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTE-- 562 + I LN E+ ++ K K++ + +LK++Q +D + S K + + Sbjct: 211 ENKYNQDIDALNKELQNQQQDFEKQKNDLQDQLKRLQDQLDKQTAESQQLKSQIENKDLE 270 Query: 563 --ELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAE--TRLKAISL 618 + +K+ +L ++K N + D D D+ K++ ++ N + + KA +L Sbjct: 271 GKDKDSEIEKLKKLLKDKDNKSKN--DLDEANANIDDLNKQLDQLRNALKDANKQKAAAL 328 Query: 619 --LESQK---FDLVQELHILQQKYDEVEDKLADISQ-LQSDQVCSEIKSVHLEEQIDALS 672 LE ++ DL +L +KY +E++ + +S E++ L+++ + L Sbjct: 329 DDLEKERDANSDLKNKLEDSDKKYKLLENQQNQSEEGARSKLAGMEVEFARLQKENNDLK 388 Query: 673 -------ASKKELALVIENLKLDKEQLYGT-------IKDLENDKEDIMNKLQ----NYI 714 A KEL IENL+ ++L + IKD E + D+ N+LQ + Sbjct: 389 PKLQDEVAKNKELQNQIENLQDQIDELKRSLAEAQKQIKDKEAEIADVKNQLQGVEASQQ 448 Query: 715 QENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKY 774 Q+N + D L+ A KI++L K+ ++ Q +D E + + +ES+ ++ Sbjct: 449 QQNANAQDTLKDKDA-KINDLNNKLKDNNKAINDLQNQLDNAKNELENLRKQLESKQNEL 507 Query: 775 KSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYT----IQEDELVNRLAVL 830 K +L ++ +D E DQ+ S +K++ E + D+ N Sbjct: 508 KDAEKKLNDAKRKNKDLETENEALQDQVDSINTDKEQQGDELANLRKMLSDQTANFKKNN 567 Query: 831 MDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAE 890 D+ + EK+L + E EN+ LQ NQI + + LQ S D++ N L K A+ Sbjct: 568 EDNKKENEKELAKKEAENRALQ--NQI-DQLKKLLQGSEEDLKNAQNELQAKDKDLAKAQ 624 Query: 891 SESTKYQTQLRDLESNL---KRITHEHQTL-----IVQKKKEIEDLEIE----FNTQIES 938 E+ + L+SNL K + E L ++ +K+ + E E N Q+E Sbjct: 625 RENERLANAQNQLQSNLEEKKNLDDELTDLKSKLAAIENEKQKAERENERLKAMNDQLEK 684 Query: 939 AIRD-KKVLNEKYEKNIEYVTQLEA---QLQEYKNNIENLNMNVEELNKMNLELIDKHVQ 994 D K L ++ + I+ +Q +A +LQ K E L+ E+L+ N + D ++ Sbjct: 685 TSDDLNKKLTDETRERIKLDSQAKAADRELQTAKAASEELSKTNEQLDNFNKDK-DNKIK 743 Query: 995 KQQTQSPDYTEQYINEINKLNALLKQKDEEII---ALNQKINNAQVSYMSMVSDYESKLA 1051 + Q++ D E+ N+++ N+ +K+ ++E+ A I+N +D + K Sbjct: 744 ELQSKVND-LEKKSNQLDDANSRIKELEDELSESEASKDDISNKLNDLQKKSNDLQKKSD 802 Query: 1052 QFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEG 1111 Q L++ ++E + K+ D + +L ++ + +I+EL L ++ +T Sbjct: 803 QMKKDLDDSQQENAKKQKENEDLQNQQRDLDKKLKAAEKRIQEL----LGENSDLHETLD 858 Query: 1112 MIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQEC 1171 I +S+++ D+ N V V + ++ + L ++ L +++ Sbjct: 859 NINTSSMQ-QGDEMNKV-IAEQAAKIKALQEAVNNSQPKGEDPNELHDKINDLMAQIKAL 916 Query: 1172 YTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLN-----TENDN-LLSTVAELRSSIS 1225 K +L+ N EL ++ + N LK+ L+ N E DN L + Sbjct: 917 QQKNNELDKENKELEAAKEASENENNDLKNDLQTKNKALSKAERDNDKLQNANKALDEAK 976 Query: 1226 SAVDQRGFEIAELWKQHLAQREADFQKTEHE---LRVQLSAFESKYEQLLDSVQSSTQEE 1282 + E+++L K +++++ D QK + E L E+L D +++ T E+ Sbjct: 977 EKIKALEDEVSDL-KALVSEKDGDLQKEKRENERLVANKDQLTKNNEELYDQLKNETTEK 1035 Query: 1283 -------TNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFX 1335 N + + + +L EHL+ ++ I +++ +E+E +K++ Sbjct: 1036 IKLDGQVKNAERDLAKANATNEELTKSNEHLQEQNDEKDAKIKELQAKLNELE-KKLSEL 1094 Query: 1336 XXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRV 1395 +L+ ++ + INE L+K + Sbjct: 1095 PGLQDEIAKQKETNNELQNNVNDLEKAGKDKDNKINE----LQKKANELENTKKDLEDVT 1150 Query: 1396 NDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQL-------VEYEKRI 1448 N+ E +L + K+ ++ ++ + + N E +++ QL E KR Sbjct: 1151 NELENTQKDLDNS-NNKNRDLEKQIKDLKKQIEDLNREKNDLKDQLDTSKLAGDELSKRD 1209 Query: 1449 E--DLTYEKESELAILRLKMHENANH---YETMQKESEIERV-KLIEELNVKITESVSLN 1502 E D ++ +ELA + AN E KE+E+E + K +E+ ++ E Sbjct: 1210 EVLDNLRKQIAELAAKNKDLENKANDNNAEELAAKEAELENINKQLEQTKKELAERDEEL 1269 Query: 1503 KQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFAS 1562 K N A E+E K N L+ ++ ++ L +E NL + A SK+ + Sbjct: 1270 KNAKNENLAKEKENQKLNRENERLKFEQQDLKDLEEENKNLDDENAALKSKVNALENDLQ 1329 Query: 1563 DTKQGRDE-QLDNTMNKELLD 1582 K+ D +L+N + +D Sbjct: 1330 KAKRDADRLKLNNDQLQTNID 1350 Score = 116 bits (278), Expect = 7e-24 Identities = 173/837 (20%), Positives = 358/837 (42%), Gaps = 67/837 (8%) Query: 765 ENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELV 824 E + ++ ++I +E+ A E +K +QL LQ++++A + + + L Sbjct: 75 EYLTERQNQTDNQIKESKENQAKYEATLRQAVKKHNQLTKLLQDREQAIARSGEEVENLN 134 Query: 825 NRL----AVLMDHDRVVEKQLLEIEHENKELQKKNQ---ILLEENQNLQISLSDM-QQHY 876 N+L L D + ++ + EN+ L+K+ Q L + NL SL + + Sbjct: 135 NKLDEAEKKLKDTLNDLNPKIDSLTAENENLKKQLQEQAPKLADMDNLTKSLKKLTRMQE 194 Query: 877 NALVEKANRTDLAESESTKYQTQL----RDLESNLKRITHEHQTLIVQKKKEIEDLEIEF 932 A E N+ + KY + ++L++ + + L Q K+ + L+ + Sbjct: 195 KAKQELENQKKQNADQENKYNQDIDALNKELQNQQQDFEKQKNDLQDQLKRLQDQLDKQT 254 Query: 933 --NTQIESAIRDKKVLNEKYEKNIEYVTQ-LEAQLQEYKNNIENLNMNVEELNKMNLELI 989 + Q++S I +K + + + IE + + L+ + + KN+++ N N+++LNK +L Sbjct: 255 AESQQLKSQIENKDLEGKDKDSEIEKLKKLLKDKDNKSKNDLDEANANIDDLNKQLDQLR 314 Query: 990 D--KHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYE 1047 + K KQ+ + D E+ + + L L+ D++ L + N ++ Sbjct: 315 NALKDANKQKAAALDDLEKERDANSDLKNKLEDSDKKYKLLENQQNQSE-------EGAR 367 Query: 1048 SKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIP 1107 SKLA + +++E + +L D N+ELQ + DQI ELK + + I Sbjct: 368 SKLAGMEVEFARLQKENNDLKPKLQDEVAKNKELQNQIENLQDQIDELKRSLAEAQKQIK 427 Query: 1108 KTEGMIISSTIEPMSDDAN-NVDXXXXXXXXXXXXLKVQEEEEFIQERS-VLQEQSAKLN 1165 E I + +A+ K+ + +++ + + + +L+ Sbjct: 428 DKEAEIADVKNQLQGVEASQQQQNANAQDTLKDKDAKINDLNNKLKDNNKAINDLQNQLD 487 Query: 1166 TELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSIS 1225 E QLE+ EL ++++N K K + L TEN+ L V SI+ Sbjct: 488 NAKNELENLRKQLESKQNELKD----AEKKLNDAKRKNKDLETENEALQDQV----DSIN 539 Query: 1226 SAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNK 1285 + +Q+G E+A L K L+ + A+F+K ++K E + + + +E N+ Sbjct: 540 TDKEQQGDELANLRKM-LSDQTANFKKNNE---------DNKKE---NEKELAKKEAENR 586 Query: 1286 IVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXX 1345 + Q+ L+ LQ EE L+N Q + ++ +++ E+E++A Sbjct: 587 AL-QNQIDQLKKLLQGSEEDLKNAQNELQ--AKDKDLAKAQRENERLANAQNQLQSNLEE 643 Query: 1346 XXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLEL 1405 D T+ +S E EN +LK + ++ D + ++L Sbjct: 644 KKNLDDELTDLKSKLAAIENEKQKAERENERLKAMNDQLEKTSDDLNKKLTDETRERIKL 703 Query: 1406 THQLELKDSEIYQKTHEYTITLTQRNDEFENVRQ----QLVEYEKRIEDLTYEKESELAI 1461 Q + D E+ Q + L++ N++ +N + ++ E + ++ DL +K ++L Sbjct: 704 DSQAKAADREL-QTAKAASEELSKTNEQLDNFNKDKDNKIKELQSKVNDLE-KKSNQLDD 761 Query: 1462 LRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNE 1521 ++ E E ESE + + +LN +S L K+ ++ K L++ ++ Sbjct: 762 ANSRIKE----LEDELSESEASKDDISNKLNDLQKKSNDLQKKSDQMKKDLDD-----SQ 812 Query: 1522 MQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNK 1578 + A + +E E L ++ +L ++A+ +IQ+ + SD + D ++M + Sbjct: 813 QENAKKQKENE--DLQNQQRDLDKKLKAAEKRIQELLGENSDLHETLDNINTSSMQQ 867 Score = 103 bits (248), Expect = 3e-20 Identities = 143/736 (19%), Positives = 312/736 (42%), Gaps = 67/736 (9%) Query: 883 ANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRD 942 +N TD ++SE ++ Q L +L + L ++ H+ +I QK + + F +S Sbjct: 8 SNATDGSKSEKSQNQ-YLWELTNGLVKV-HDDIDIIDQKIGKSSAQDRSFQMNPKSIFPR 65 Query: 943 KKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPD 1002 +++ + + EY+T+ + Q N I+ N + + + KH Q T+ Sbjct: 66 LEIVCKNLD---EYLTERQNQTD---NQIKESKENQAKYEATLRQAVKKH--NQLTKLLQ 117 Query: 1003 YTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEE 1062 EQ I + EE+ LN K++ A+ ++D K+ T + EN+++ Sbjct: 118 DREQAI----------ARSGEEVENLNNKLDEAEKKLKDTLNDLNPKIDSLTAENENLKK 167 Query: 1063 EMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMS 1122 ++Q + +L D + L+ L R Q+ +EL+ K + N + + I+ ++ Sbjct: 168 QLQEQAPKLADMDNLTKSLKKLTRMQEKAKQELENQK---KQNADQENK--YNQDIDALN 222 Query: 1123 DDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLN 1182 + N + +++ ++ + Q+ +++ + E K ++E L Sbjct: 223 KELQNQQQDFEKQKNDLQDQLKRLQDQLDKQTAESQQLKSQIENKDLEGKDKDSEIEKLK 282 Query: 1183 TELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVD--QRGFEIAELWK 1240 L D ++ +++ + ++ LN + D L + + + ++A+D ++ + K Sbjct: 283 KLLKDKDNKSKNDLDEANANIDDLNKQLDQLRNALKDANKQKAAALDDLEKERDANSDLK 342 Query: 1241 QHLAQREADFQ-------KTEHELRVQLSAFESKYEQL----------LDSVQSSTQEET 1283 L + ++ ++E R +L+ E ++ +L L + +E Sbjct: 343 NKLEDSDKKYKLLENQQNQSEEGARSKLAGMEVEFARLQKENNDLKPKLQDEVAKNKELQ 402 Query: 1284 NKIVTM-EQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXX 1342 N+I + +Q+ L+ L + ++ +++ + + ADV NQ++ + + + + Sbjct: 403 NQIENLQDQIDELKRSLAEAQKQIKDKEAEIADVKNQLQGVEASQQQQNANAQDTLKDKD 462 Query: 1343 XXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKV 1402 L+ N++ +Q Q + N E L+K ++NDA+ K Sbjct: 463 AKINDLNNKLKDNNKAINDLQNQ-LDNAKNELENLRKQLESKQNELKDAEKKLNDAKRK- 520 Query: 1403 LELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQ----QLVEYEKRIEDLTYEKESE 1458 LE ++ + + Q+ DE N+R+ Q ++K ED E E E Sbjct: 521 ---NKDLETENEALQDQVDSINTDKEQQGDELANLRKMLSDQTANFKKNNEDNKKENEKE 577 Query: 1459 LAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAK 1518 LA + N + ++K + E+L E + +K +A+ + E Sbjct: 578 LAKKEAENRALQNQIDQLKKLLQGSE----EDLKNAQNELQAKDKDLAKAQRENERLANA 633 Query: 1519 TNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNT--- 1575 N++Q+ LE ++ L+DE+T+L++ + A ++ QK ++ + ++QL+ T Sbjct: 634 QNQLQSNLEEKK----NLDDELTDLKSKLAAIENEKQK-AERENERLKAMNDQLEKTSDD 688 Query: 1576 MNKELLDAV-PRAELD 1590 +NK+L D R +LD Sbjct: 689 LNKKLTDETRERIKLD 704 Score = 72.1 bits (169), Expect = 1e-10 Identities = 115/575 (20%), Positives = 232/575 (40%), Gaps = 41/575 (7%) Query: 149 NTIKEKDNALSVLQVKMKIMETTILDLQEK---INEKDQIIEAKNKATTXXXXXXXXXXX 205 N + E + Q K +E T +L++ +NEK + ++ N Sbjct: 1776 NQLNELQKKFNESQKKANQLEPTKQELEDSRNDLNEKQKELDESNNKNRDLEKQIKELKK 1835 Query: 206 XXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARF 265 ED K+Q +QE + + D +L K I ++ LE NK + Sbjct: 1836 QI----EDLKKQKDDLQEQ-LDNNVKADDVIDKLRKQIAELLAKVKELEAKNK--DNTGD 1888 Query: 266 EISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELT 325 E++++ +++ Q L + S S ++K E++ K + E+ + ++ Sbjct: 1889 ELAVKDAEIESLKNQFEQAKKDLDEKELELKQTSDNLSSKDK-ELQ-KANRELERLQDVD 1946 Query: 326 KKIELLEHLNCQIRQTNKELENKLATMGTE---SKAVSSPSKKGSPLISRKSGRNTASKM 382 +++ N ++ N EL+ +LA E SK + + + +++ + Sbjct: 1947 QELAQANEENKKLDAENGELKTQLANTENELQKSKQDNERLQSSNDQLTKNTDDLNKKLT 2006 Query: 383 KSPWSQLSSETLNQDTDKKINKNE--IAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXX 440 + L Q+ +++ N+ IA+ I LN+ DK+ I + Sbjct: 2007 DETTDNIKLNGLIQELQRRLANNDAAIAQQAESIDKLNEQAADKDNKIKDLHDQINNLQK 2066 Query: 441 XXXGKDTLIAQL-----QLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQL---KQELNDE 492 D L QL QL+ + + NE K QL KQEL D Sbjct: 2067 KANDADNLQQQLDYAKSQLDEANKSNNDKDNQLNELQKKFNESQKKANQLEPTKQELEDS 2126 Query: 493 IKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSD 552 D+N EK K +E + N +++ K + K N + + +Q +D+ D Sbjct: 2127 RNDLN-----EKQKELDESNNK-NRDLEKQIKELKKQIGNLDSEKQALQDKLDDIKLADD 2180 Query: 553 SNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMI----ESDVYKKMIEM--E 606 + I + E L +L +++AEL + +L+ D ++ + E + K +E + Sbjct: 2181 A---ISKRDEVLDNLRKQIAELAAKNKDLENKANDNNAEELAAKEAELENINKQLEQTKK 2237 Query: 607 NLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEE 666 LAE R + + +++ +E L ++ + ++ + D+ L+ + + ++ L+ Sbjct: 2238 ELAE-RDEELKNAKNENLAKEKENQKLNRENERLKFEQQDLKDLEEENKNLDDENAALKS 2296 Query: 667 QIDALSASKKELALVIENLKLDKEQLYGTIKDLEN 701 +++AL ++ + LKL+ +QL I DL+N Sbjct: 2297 KVNALENDLQKAKRDADRLKLNNDQLQTNIDDLDN 2331 >UniRef50_UPI00006CE95F Cluster: Viral A-type inclusion protein repeat containing protein; n=1; Tetrahymena thermophila SB210|Rep: Viral A-type inclusion protein repeat containing protein - Tetrahymena thermophila SB210 Length = 1668 Score = 181 bits (441), Expect = 1e-43 Identities = 298/1476 (20%), Positives = 633/1476 (42%), Gaps = 131/1476 (8%) Query: 147 LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINE--KDQIIEAKNKATTXXXXXXXXXX 204 L +KEK+NA LQ ++K+ E + L++ +++ + QI E +N Sbjct: 271 LDQALKEKENAQKELQDQLKMKEDEVEQLKKDLDQQKQQQIQEVQN-------------- 316 Query: 205 XXXXXXXEDTKQQMTKMQENFIAMEAEWKDE---KQRLLKDIESKDVRISSLEEANKLLE 261 +D +++ +QE +E++ +E KQ+L++++E K ++S L++ L++ Sbjct: 317 -----LKQDQSKEVLTLQEKIGVLESKVSEETASKQKLIEEVEQKGKQVSQLQDQINLIK 371 Query: 262 AARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPS---CEEKTEIEE--KGSL 316 + S + KL ++ Q ++ S EE ++ +E K + Sbjct: 372 E---QSSSDQDKLMEQKNQEIKELKDQIENIQQKIEEQTNSSNSLSEELSQAKEELKKAQ 428 Query: 317 EIANMTELTKKI--ELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKS 374 E ++E K+ E + LN QI + + +++ + + ++ +K I Sbjct: 429 EQFQLSEKEKQTLKEQISQLNLQIEEKSTQIQEVQNELSQKLNEIAQKDEK----IKHLE 484 Query: 375 GRNTASKMKSPWSQLSSETLNQDTDKKINKN-EIAKLEMVIQSLNKDLVDKEYVISEKDT 433 NT+S +S +L E N+ ++ I K+ +I L + IQ+ K+ +++ + EK+ Sbjct: 485 SENTSSLSQS--EELGKE-FNEIREQMIQKDQQIDNLNVNIQAKEKE-YNEQLQLKEKEY 540 Query: 434 XXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEI 493 K+ QL + + + I + + + + + E+LKQ + E Sbjct: 541 SEKLDKINEEIKNLNEVISQLNEENKI---AKIQIEESNKSIQKYENDIEELKQNIETEK 597 Query: 494 K--DVNVKDLIEKLKSAEEQITQLN----DEIDAANKNMIKVKSNHKLKLKQMQKTI--- 544 K + + +L E K E I N E++ N N ++ +N + +L ++Q+ I Sbjct: 598 KQSENQITELQEIHKKQIEDINSQNIAKIQELENKNVNQVQEINNSQDQLHKLQEEIKSL 657 Query: 545 -DNFSKVSDSNKEI-VRLTEELHHLSQKVAELEEEKGNL----QLHLVDYDSGRMIESDV 598 + +K++D NK I ++L E + +++ +++E NL Q + + ++ Sbjct: 658 NEQIAKLNDENKIINIQLEESTKSIQKQIQDIKELSENLETQKQSAQEEIQKQKSELEEL 717 Query: 599 YKKMIE-MENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCS 657 +KK IE + N T+++ + S K + + H ++ +E+ED +++ + Sbjct: 718 HKKQIESINNQNNTKIQELENSHSNKVEELNNSH--KKLIEELEDSHKKVTEDIQHKNAH 775 Query: 658 EIKSVH--LEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLEN---DKEDIMNKLQN 712 E+K + L E + +++++L + + + IKDLEN +K D M L++ Sbjct: 776 ELKKIQEILSETQQREKSLQEQISLHSMGAEQQEVERQKIIKDLENQIKEKADQMRNLED 835 Query: 713 YIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELS 772 I+ D K ++ EK + + + +E + +T + A ++ NI + Sbjct: 836 QIELLNDQNSK-QQADNEKQNLQIQDLTQKEAQQQETINKLKADLENAKQIELNINEQNE 894 Query: 773 KYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMD 832 +K +LEES + + LE + L + + + Q ++L+N L Sbjct: 895 AFKK---QLEESKQNLSQLQKELEESSKNLSDSKENQNEEILSLKKQIEDLLNLKTELET 951 Query: 833 HDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESE 892 + + EI+ E Q+K EE Q SL D ++ + +++ T+L + + Sbjct: 952 SNNKINTLNQEIDALKNEKQQKE----EEYQKQINSLKDQSKNNDNNIQQ--ETELLKQQ 1005 Query: 893 STKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIE--SAIRDKKVLNEKY 950 + K + QL++L+ + +I E I K+KE++D + Q+ + ++D+ ++ Sbjct: 1006 NKKLEEQLKELKDSELQILEE----IQNKEKEVDDFKQINEQQLNEINQLKDELASQKQK 1061 Query: 951 EKNIEYVTQLEAQLQEYKNNIENLNMNVE-ELNKMNLELIDKHVQKQQTQSPDYTEQYIN 1009 + E TQ E+QL E K E + ++++ +L ++N + K + Q + D+ ++ + Sbjct: 1062 DNQQEQETQGESQLDELKVKYEQVELDLKSKLEEIN--QLQKQNENLQREKLDFEKEIAD 1119 Query: 1010 EINKLNALLKQKDEEIIAL-NQKINNAQVSYMSM-----VSDYESKLAQFTTKLENMEEE 1063 ++LN+ II L N +N++ S V++ E K + ++ +EE Sbjct: 1120 MKSQLNSTAFSSSNNIINLENSAMNDSTTPRNSSLVSTPVNNEEKKDNEDKKDEKDKKEE 1179 Query: 1064 MQRVSKQLLDSKQHNEELQI-LVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMS 1122 + SK+ KQ ++ + +++ D+Q+KELK+ + E + + + + +P+ Sbjct: 1180 KDKKSKEAKSDKQQTVKMTLEELKKWDEQVKELKKKRKELEKENKQLKQELEEKSKQPVQ 1239 Query: 1123 --DDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLET 1180 D ++ LK++ EE+ ++S Q+ LN E E +I+Q Sbjct: 1240 NIDSLKQIESQKRQLEQQYMNLKIELEEKNKLQQS--QQIKKNLNLESLEERCRILQ--- 1294 Query: 1181 LNTELTGHDVVNQEQINQLKSKLEQLNTE-NDNLLSTVAELRSSISSAVDQRGFEIAELW 1239 L + VN ++ ++ + ++ T ++ + EL+ SA ++ E+ L Sbjct: 1295 ---GLLDENSVNLQKADREREYWKEKYTGLQEDFNAKEEELKIQRESAREKFNLEMT-LQ 1350 Query: 1240 KQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKI-VTMEQVTSLQNK 1298 Q + Q E+E +Q + + L + +E +K+ +E Q K Sbjct: 1351 SQIQQNSSLNKQIQEYERNLQAYKQLNADNENLKKECAKLRELVDKLQEELENKERNQEK 1410 Query: 1299 LQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQS 1358 L K L L ++Y IN +E ++++K + +++ NQ Sbjct: 1411 LSHKLNELNELNDEYQKKINYLEKQSERLQNQK-SELEQNLQSITTQLEDSQNIQKINQK 1469 Query: 1359 YKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQ 1418 Q + I + + Q K + +A K T + + E + Sbjct: 1470 KYQNEVLEIKQVRDGLVQQVKELKTKNESLENDVRSLREANKKQFHSTINV---NPETAK 1526 Query: 1419 KTHEYTITLTQRNDEFE-NVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQ 1477 K +L+ RN E E N Q L+ +++ ++ IL+++ + + E M Sbjct: 1527 KDKIILESLSIRNQELEVNFNQNLI---------SFKANKQIVILKVQSKQQKDKIEFMD 1577 Query: 1478 KE-SEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTL 1536 K+ EI +V L KI +L+K++ N E++ E + E + +++ Sbjct: 1578 KQIKEIHKV-----LESKIAIIQNLSKELFHKNPT-SEDIKDIYEQKELQEVKNYKLMNY 1631 Query: 1537 NDEITNLQNMVRASSSKIQKHV-SFASDTKQGRDEQ 1571 EI +L + + +++K+V + K+ D Q Sbjct: 1632 K-EIQDLIEKMSIENIRMRKNVLILGQELKEAMDSQ 1666 Score = 178 bits (434), Expect = 9e-43 Identities = 309/1496 (20%), Positives = 647/1496 (43%), Gaps = 150/1496 (10%) Query: 152 KEKDNAL---SVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXX 208 KE+D+ L S + + + +E + L+E+ ++ Q ++++A Sbjct: 47 KEQDDILIQLSTIDSEKQELEKELQQLKEQ-QQQSQGNSSESEALQQELNKQKDKHSELE 105 Query: 209 XXXEDTKQQMTKMQENFIAMEA-EWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEI 267 + K K+Q +++ +++++ Q+ K I + +I +E NK L E+ Sbjct: 106 LEINNLKDTNQKLQAKIEEIQSHKYEEQIQQNEKKIAELNSQIDKQDEENKSLNGKLQEL 165 Query: 268 SLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGS-LEIAN--MTEL 324 E Q++ Q L +++ E K +++ K + AN + +L Sbjct: 166 ESEIKSTHQQIAQKEQDLQKQKEDSDSLLEKTKLELEENKKQLDIKNQEINDANQKVNDL 225 Query: 325 TKKIELLEHLNCQIRQTNKELENKLAT-----MGTESKAVSSPSKKGSPLISRKSGRNTA 379 K++ N + + K+LE+K++ G ++K +S KK + K Sbjct: 226 ENKLKDSGSTNEEFQLKQKDLEDKISQADETKQGLQNK-LSELEKKLDQALKEKENAQKE 284 Query: 380 SKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXX 439 + + + E L +D D++ + +I +++ + Q +K+++ + I ++ Sbjct: 285 LQDQLKMKEDEVEQLKKDLDQQ-KQQQIQEVQNLKQDQSKEVLTLQEKIGVLESKVSEET 343 Query: 440 XXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVK 499 K LI +++ + +Q + I++ + ++ K+ EQ QE+ E+KD ++ Sbjct: 344 AS---KQKLIEEVEQKGKQVSQLQDQINL-IKEQSSSDQDKLMEQKNQEIK-ELKD-QIE 397 Query: 500 DLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVS-DSNKEIV 558 ++ +K++ L++E+ A + + K + +L K+ Q + S+++ ++ Sbjct: 398 NIQQKIEEQTNSSNSLSEELSQAKEELKKAQEQFQLSEKEKQTLKEQISQLNLQIEEKST 457 Query: 559 RLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISL 618 ++ E + LSQK+ E+ ++ ++ HL ++ + +S+ K E + E + Sbjct: 458 QIQEVQNELSQKLNEIAQKDEKIK-HLESENTSSLSQSEELGK--EFNEIREQMI----- 509 Query: 619 LESQKFDLVQELHI-LQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKE 677 QK + L++ +Q K E ++L ++K E++D ++ K Sbjct: 510 ---QKDQQIDNLNVNIQAKEKEYNEQL-------------QLKEKEYSEKLDKINEEIKN 553 Query: 678 LALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLA 737 L VI +L++E I+ E++K + K +N I+E + +K S +I+EL Sbjct: 554 LNEVIS--QLNEENKIAKIQIEESNKS--IQKYENDIEELKQNIETEKKQSENQITEL-Q 608 Query: 738 KINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLER 797 +I+ ++ I +Q I AKIQE + N E++ + ++ +L+E I + ++ L Sbjct: 609 EIHKKQIEDINSQ-NI-AKIQELENKNVNQVQEINNSQDQLHKLQEEIKSLNEQIAKLND 666 Query: 798 KADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDH-DRVVEKQLLEIEHENKELQKKNQ 856 + + L+E K+ + EL L ++KQ E+E EL KK Q Sbjct: 667 ENKIINIQLEESTKSIQKQIQDIKELSENLETQKQSAQEEIQKQKSELE----ELHKK-Q 721 Query: 857 ILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQT 916 I NQN + +++ ++ VE+ N + ++ + +LE + K++T + Q Sbjct: 722 IESINNQN-NTKIQELENSHSNKVEELNNS---------HKKLIEELEDSHKKVTEDIQH 771 Query: 917 LIVQKKKEIEDLEIEFNTQIESAIRDKKVLN----EKYE-KNIEYVTQLEAQLQEYKNNI 971 + K+I+++ E Q E +++++ L+ E+ E + + + LE Q++E + + Sbjct: 772 KNAHELKKIQEILSE-TQQREKSLQEQISLHSMGAEQQEVERQKIIKDLENQIKEKADQM 830 Query: 972 ENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINE---INKLNALLKQKDEEIIAL 1028 NL +E LN N + + +KQ Q D T++ + INKL A L+ + I L Sbjct: 831 RNLEDQIELLNDQNSKQQADN-EKQNLQIQDLTQKEAQQQETINKLKADLENAKQ--IEL 887 Query: 1029 NQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQ 1088 N IN ++ + + + L+Q +++E++ SK L DSK++ E + +++Q Sbjct: 888 N--INEQNEAFKKQLEESKQNLSQ-------LQKELEESSKNLSDSKENQNEEILSLKKQ 938 Query: 1089 DDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEE 1148 + + LK T+L N T ++ I+ + ++ + + Sbjct: 939 IEDLLNLK-TELETSNNKINT----LNQEIDALKNEKQQKEEEYQKQINSLKDQSKNNDN 993 Query: 1149 EFIQERSVLQEQSAKLNTELQECYTKIIQL--ETLNTELTGHDV--VNQEQINQLKSKLE 1204 QE +L++Q+ KL +L+E +Q+ E N E D +N++Q+N++ + Sbjct: 994 NIQQETELLKQQNKKLEEQLKELKDSELQILEEIQNKEKEVDDFKQINEQQLNEINQLKD 1053 Query: 1205 QLNTENDNLLSTVAELRSSISSAVDQRG--FEIAELWKQHLAQREADFQKTEHELRVQLS 1262 +L ++ E + S +D+ +E EL + + QK L+ + Sbjct: 1054 ELASQKQK--DNQQEQETQGESQLDELKVKYEQVELDLKSKLEEINQLQKQNENLQREKL 1111 Query: 1263 AFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLR----NLQEKYADVIN 1318 FE + + + S+ +N I+ +E +++ + + L N +EK + Sbjct: 1112 DFEKEIADMKSQLNSTAFSSSNNIINLEN-SAMNDSTTPRNSSLVSTPVNNEEKKDNEDK 1170 Query: 1319 QIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLK 1378 + E + E +D+K +L+ ++ K+++++ + +EN QLK Sbjct: 1171 KDEKDKKEEKDKKSK--EAKSDKQQTVKMTLEELKKWDEQVKELKKKR-KELEKENKQLK 1227 Query: 1379 KSSXXXXXXXXXXXXRVNDAEAKVLELTHQ-----LELKDSEIYQKTHEYTITLTQRN-D 1432 + + E++ +L Q +EL++ Q++ + L + + Sbjct: 1228 QELEEKSKQPVQNIDSLKQIESQKRQLEQQYMNLKIELEEKNKLQQSQQIKKNLNLESLE 1287 Query: 1433 EFENVRQQLVEYEKRIEDLTYEKESEL---AILRLKMHENANHYET-MQKESEIERVKLI 1488 E + Q L++ E + ++E E L+ NA E +Q+ES E+ L Sbjct: 1288 ERCRILQGLLD-ENSVNLQKADREREYWKEKYTGLQEDFNAKEEELKIQRESAREKFNLE 1346 Query: 1489 EELNVKITESVSLNKQVAEL-------------NKALEEEVAKTNEM----QTALENQEI 1531 L +I ++ SLNKQ+ E N+ L++E AK E+ Q LEN+E Sbjct: 1347 MTLQSQIQQNSSLNKQIQEYERNLQAYKQLNADNENLKKECAKLRELVDKLQEELENKER 1406 Query: 1532 ----------EIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMN 1577 E+ LNDE N + S ++Q S Q QL+++ N Sbjct: 1407 NQEKLSHKLNELNELNDEYQKKINYLEKQSERLQNQKSELEQNLQSITTQLEDSQN 1462 Score = 166 bits (403), Expect = 5e-39 Identities = 233/1210 (19%), Positives = 517/1210 (42%), Gaps = 79/1210 (6%) Query: 404 KNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGP 463 K ++A+L++V K+ +KE + EK D LI ++ ++ Sbjct: 11 KEQVAQLKVVTYEKVKETQEKEKQLEEKKQEIKKLQKEQD--DILIQLSTIDSEKQELEK 68 Query: 464 SLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDL-IEKLKSAEEQITQLNDEIDAA 522 L + + + E L+QELN + + +L I LK +++ +EI + Sbjct: 69 ELQQLKEQQQQSQGNSSESEALQQELNKQKDKHSELELEINNLKDTNQKLQAKIEEIQS- 127 Query: 523 NKNMIKVKSNHKLKLKQMQKTIDNFSKVSDS-NKEIVRLTEELHHLSQKVAELEEEKGNL 581 +K +++ N K K+ ++ ID + + S N ++ L E+ Q++A+ E++ L Sbjct: 128 HKYEEQIQQNEK-KIAELNSQIDKQDEENKSLNGKLQELESEIKSTHQQIAQKEQD---L 183 Query: 582 QLHLVDYDS---GRMIESDVYKKMIEMENLA-ETRLKAISLLESQKFDLVQELHILQQKY 637 Q D DS +E + KK ++++N + ++ LE++ D Q K Sbjct: 184 QKQKEDSDSLLEKTKLELEENKKQLDIKNQEINDANQKVNDLENKLKDSGSTNEEFQLKQ 243 Query: 638 DEVEDKLADISQLQSDQVCSEIKSVHLEEQID-ALSASKKELALVIENLKLDKEQLYGTI 696 ++EDK ISQ + + K LE+++D AL + + + LK+ ++++ Sbjct: 244 KDLEDK---ISQADETKQGLQNKLSELEKKLDQALKEKENAQKELQDQLKMKEDEVEQLK 300 Query: 697 KDLENDKEDIMNKLQNYIQEN----MDLTDKL----EKMSAEKISE--LLAKINHE--EQ 744 KDL+ K+ + ++QN Q+ + L +K+ K+S E S+ L+ ++ + + Sbjct: 301 KDLDQQKQQQIQEVQNLKQDQSKEVLTLQEKIGVLESKVSEETASKQKLIEEVEQKGKQV 360 Query: 745 SKIQTQFGI--DAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQL 802 S++Q Q + + ++D +E E+ + K +I +++ I E++ S +++L Sbjct: 361 SQLQDQINLIKEQSSSDQDKLMEQKNQEIKELKDQIENIQQKI---EEQTNSSNSLSEEL 417 Query: 803 GSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEEN 862 +E +KA ++ + E E + + +E++ +I+ EL +K + +++ Sbjct: 418 SQAKEELKKAQEQFQLSEKEKQTLKEQISQLNLQIEEKSTQIQEVQNELSQKLNEIAQKD 477 Query: 863 QNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKK 922 + ++ S+ + E + + + Q+ +L N++ E+ + K+ Sbjct: 478 EKIKHLESENTSSLSQSEELGKEFNEIREQMIQKDQQIDNLNVNIQAKEKEYNEQLQLKE 537 Query: 923 KEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELN 982 KE + + N +I++ LNE+ + + + +Q+Y+N+IE L N+E Sbjct: 538 KEYSEKLDKINEEIKNLNEVISQLNEENKIAKIQIEESNKSIQKYENDIEELKQNIETEK 597 Query: 983 KMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSM 1042 K + I + + + Q D Q I +I +L + +EI +++ Q S+ Sbjct: 598 KQSENQITELQEIHKKQIEDINSQNIAKIQELENKNVNQVQEINNSQDQLHKLQEEIKSL 657 Query: 1043 VSDYESKLAQFTTKLEN--MEEEMQRVSKQLLDSKQHNEELQILVREQDDQI-KELKETK 1099 ++ +KL K+ N +EE + + KQ+ D K+ +E L+ + ++I K+ E + Sbjct: 658 -NEQIAKLND-ENKIINIQLEESTKSIQKQIQDIKELSENLETQKQSAQEEIQKQKSELE 715 Query: 1100 LTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQE 1159 + I + E + +N V+ L E+ + +Q Sbjct: 716 ELHKKQIESINNQNNTKIQELENSHSNKVEELNNSHKKLIEEL----EDSHKKVTEDIQH 771 Query: 1160 QSAKLNTELQECYTKIIQLE-TLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVA 1218 ++A ++QE ++ Q E +L +++ H + ++Q + + ++ L + + Sbjct: 772 KNAHELKKIQEILSETQQREKSLQEQISLHSMGAEQQEVERQKIIKDLENQIKEKADQMR 831 Query: 1219 ELRSSISSAVDQRGFEIAELWKQH-----LAQREADFQKTEHELRVQL---SAFESKYEQ 1270 L I DQ + A+ KQ+ L Q+EA Q+T ++L+ L E + Sbjct: 832 NLEDQIELLNDQNSKQQADNEKQNLQIQDLTQKEAQQQETINKLKADLENAKQIELNINE 891 Query: 1271 LLDSVQSSTQEETNKIVTM-----EQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRS 1325 ++ + +E + + E +L + +++ E + +L+++ D++N L++ Sbjct: 892 QNEAFKKQLEESKQNLSQLQKELEESSKNLSDSKENQNEEILSLKKQIEDLLN----LKT 947 Query: 1326 EIE--DEKV-AFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSX 1382 E+E + K+ + + + S K + + NI +E LK+ + Sbjct: 948 ELETSNNKINTLNQEIDALKNEKQQKEEEYQKQINSLKDQSKNNDNNIQQETELLKQQN- 1006 Query: 1383 XXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLV 1442 + D+E ++LE E + + Q + + Q DE + +Q+ Sbjct: 1007 ---KKLEEQLKELKDSELQILEEIQNKEKEVDDFKQINEQQLNEINQLKDELASQKQKDN 1063 Query: 1443 EYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKI-TESVSL 1501 + E+ + ES+L L++K + + +S++E + +++ N + E + Sbjct: 1064 QQEQETQG-----ESQLDELKVKYEQ-----VELDLKSKLEEINQLQKQNENLQREKLDF 1113 Query: 1502 NKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFA 1561 K++A++ L ++ LEN + T + + V K + Sbjct: 1114 EKEIADMKSQLNSTAFSSSNNIINLENSAMNDSTTPRNSSLVSTPVNNEEKKDNEDKKDE 1173 Query: 1562 SDTKQGRDEQ 1571 D K+ +D++ Sbjct: 1174 KDKKEEKDKK 1183 Score = 122 bits (295), Expect = 6e-26 Identities = 141/841 (16%), Positives = 360/841 (42%), Gaps = 37/841 (4%) Query: 775 KSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHD 834 K + +E +A ++ Y ++ + L+EK++ + ++D+++ +L+ + Sbjct: 4 KEELAFFKEQVAQLKVVTYEKVKETQEKEKQLEEKKQEIKKLQKEQDDILIQLSTIDSEK 63 Query: 835 RVVEKQLLEIEHENKELQ---KKNQILLEENQNLQISLSDMQQHYNALVEKANR--TDLA 889 + +EK+L +++ + ++ Q +++ L +E + S+++ N L + + + Sbjct: 64 QELEKELQQLKEQQQQSQGNSSESEALQQELNKQKDKHSELELEINNLKDTNQKLQAKIE 123 Query: 890 ESESTKYQTQLRDLESNLKRITHEHQTLIVQKKK---EIEDLEIEFNTQIESAIRDKKVL 946 E +S KY+ Q++ E + + + + K ++++LE E + + + ++ L Sbjct: 124 EIQSHKYEEQIQQNEKKIAELNSQIDKQDEENKSLNGKLQELESEIKSTHQQIAQKEQDL 183 Query: 947 NEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQ 1006 ++ E + + + + +L+E K ++ N +E+N N ++ D ++ + S E+ Sbjct: 184 QKQKEDSDSLLEKTKLELEENKKQLDIKN---QEINDANQKVND--LENKLKDSGSTNEE 238 Query: 1007 YINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQR 1066 + + L + Q DE L K++ + + + E+ + +L+ E+E+++ Sbjct: 239 FQLKQKDLEDKISQADETKQGLQNKLSELEKKLDQALKEKENAQKELQDQLKMKEDEVEQ 298 Query: 1067 VSKQLLDSKQHN-EELQILVREQDDQIKELKETKLTFEMNIPK---TEGMIISST----- 1117 + K L KQ +E+Q L ++Q ++ L+E E + + ++ +I Sbjct: 299 LKKDLDQQKQQQIQEVQNLKQDQSKEVLTLQEKIGVLESKVSEETASKQKLIEEVEQKGK 358 Query: 1118 -IEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKII 1176 + + D N + K QE +E + +Q++ + ++ Sbjct: 359 QVSQLQDQINLIKEQSSSDQDKLMEQKNQEIKELKDQIENIQQKIEEQTNSSNSLSEELS 418 Query: 1177 QLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSIS---SAVDQRGF 1233 Q + + +++++ LK ++ QLN + + + + E+++ +S + + Q+ Sbjct: 419 QAKEELKKAQEQFQLSEKEKQTLKEQISQLNLQIEEKSTQIQEVQNELSQKLNEIAQKDE 478 Query: 1234 EIAELWKQH---LAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTME 1290 +I L ++ L+Q E + K +E+R Q+ + + + L ++Q+ +E ++ E Sbjct: 479 KIKHLESENTSSLSQSE-ELGKEFNEIREQMIQKDQQIDNLNVNIQAKEKEYNEQLQLKE 537 Query: 1291 QVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXX 1350 + S KL E ++NL E + + + +I + +IE+ + Sbjct: 538 KEYS--EKLDKINEEIKNLNEVISQLNEENKIAKIQIEESNKSIQKYENDIEELKQNIET 595 Query: 1351 DLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLE 1410 + + ++QE I + N+Q +N+++ ++ +L +++ Sbjct: 596 EKKQSENQITELQEIHKKQIEDINSQNIAKIQELENKNVNQVQEINNSQDQLHKLQEEIK 655 Query: 1411 LKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKES-ELAILRLKMHEN 1469 + +I + E I Q + +++++Q+ + ++ E+L +K+S + I + K Sbjct: 656 SLNEQIAKLNDENKIINIQLEESTKSIQKQIQDIKELSENLETQKQSAQEEIQKQKSELE 715 Query: 1470 ANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQ 1529 H + ++ + K+ E N + LN +L + LE+ K E Sbjct: 716 ELHKKQIESINNQNNTKIQELENSHSNKVEELNNSHKKLIEELEDSHKKVTE--DIQHKN 773 Query: 1530 EIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMN--KELLDAVPRA 1587 E+ + + ++ Q ++ +I H A + R + + + N KE D + Sbjct: 774 AHELKKIQEILSETQQREKSLQEQISLHSMGAEQQEVERQKIIKDLENQIKEKADQMRNL 833 Query: 1588 E 1588 E Sbjct: 834 E 834 Score = 88.2 bits (209), Expect = 2e-15 Identities = 180/917 (19%), Positives = 391/917 (42%), Gaps = 97/917 (10%) Query: 172 ILDLQEKINEK-DQI--IEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAM 228 I DL+ +I EK DQ+ +E + + +D Q+ + QE + Sbjct: 816 IKDLENQIKEKADQMRNLEDQIELLNDQNSKQQADNEKQNLQIQDLTQKEAQQQETINKL 875 Query: 229 EAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXX 288 +A+ ++ KQ L E + LEE+ + L + E+ L+ E Sbjct: 876 KADLENAKQIELNINEQNEAFKKQLEESKQNLSQLQKELEESSKNLSDSKENQNEEILSL 935 Query: 289 XXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENK 348 K+ IE KTE+E + + L ++I+ L++ + +Q +E + + Sbjct: 936 --------KKQIEDLLNLKTELETSNN----KINTLNQEIDALKN---EKQQKEEEYQKQ 980 Query: 349 LATMGTESKAVSSPSKKGSPLISRKSGR--NTASKMKSPWSQLSSETLNQDTD----KKI 402 + ++ +SK + ++ + L+ +++ + ++K Q+ E N++ + K+I Sbjct: 981 INSLKDQSKNNDNNIQQETELLKQQNKKLEEQLKELKDSELQILEEIQNKEKEVDDFKQI 1040 Query: 403 NKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEG 462 N+ ++ + I L +L ++ +KD D +L+++++Q +E Sbjct: 1041 NEQQLNE----INQLKDELASQK----QKDNQQEQETQGESQLD----ELKVKYEQ-VE- 1086 Query: 463 PSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDV-NVKDLIEKLK-SAEEQITQL----- 515 + + + E++N++ K E L++E D K++ ++K + S+ I L Sbjct: 1087 ---LDLKSKLEEINQLQKQNENLQREKLDFEKEIADMKSQLNSTAFSSSNNIINLENSAM 1143 Query: 516 NDEIDAANKNMIKVKSNHKLKL--------KQMQKTIDNFSKVSDSNKE-IVRLT-EELH 565 ND N +++ N++ K K ++ D SK + S+K+ V++T EEL Sbjct: 1144 NDSTTPRNSSLVSTPVNNEEKKDNEDKKDEKDKKEEKDKKSKEAKSDKQQTVKMTLEELK 1203 Query: 566 HLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFD 625 ++V EL++++ L+ + +++ E + ++ +ESQK Sbjct: 1204 KWDEQVKELKKKRKELEKE----------NKQLKQELEEKSKQPVQNIDSLKQIESQKRQ 1253 Query: 626 LVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENL 685 L Q+ L+ + +E ++KL QS Q+ + LEE+ L E ++ ++ Sbjct: 1254 LEQQYMNLKIELEE-KNKLQ-----QSQQIKKNLNLESLEERCRILQGLLDENSVNLQKA 1307 Query: 686 KLDKE---QLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHE 742 ++E + Y +++ N KE+ + + +E +L L+ + S L K E Sbjct: 1308 DREREYWKEKYTGLQEDFNAKEEELKIQRESAREKFNLEMTLQSQIQQNSS--LNKQIQE 1365 Query: 743 EQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQL 802 + +Q ++A EN++ E +K + + +L+E + E + L K ++L Sbjct: 1366 YERNLQAYKQLNADN-------ENLKKECAKLRELVDKLQEELENKERNQEKLSHKLNEL 1418 Query: 803 GSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEEN 862 E QK + Q + L N+ + L + + + QL + ++ K QKK Q + E Sbjct: 1419 NELNDEYQKKINYLEKQSERLQNQKSELEQNLQSITTQLEDSQNIQKINQKKYQNEVLEI 1478 Query: 863 QNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKK 922 + ++ L + E + E+ K Q N+ T + +I++ Sbjct: 1479 KQVRDGLVQQVKELKTKNESLENDVRSLREANKKQFH---STINVNPETAKKDKIILESL 1535 Query: 923 K-EIEDLEIEFNTQIESAIRDKK--VLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVE 979 ++LE+ FN + S +K+ +L + ++ + + ++ Q++E +E+ ++ Sbjct: 1536 SIRNQELEVNFNQNLISFKANKQIVILKVQSKQQKDKIEFMDKQIKEIHKVLESKIAIIQ 1595 Query: 980 ELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSY 1039 L+K EL K+ + + Y ++ + E+ K L+ K+ + + I N ++ Sbjct: 1596 NLSK---ELFHKNPTSEDIKD-IYEQKELQEV-KNYKLMNYKEIQDLIEKMSIENIRMRK 1650 Query: 1040 MSMVSDYESKLAQFTTK 1056 ++ E K A + K Sbjct: 1651 NVLILGQELKEAMDSQK 1667 >UniRef50_Q22RF4 Cluster: Viral A-type inclusion protein repeat containing protein; n=1; Tetrahymena thermophila SB210|Rep: Viral A-type inclusion protein repeat containing protein - Tetrahymena thermophila SB210 Length = 3640 Score = 181 bits (441), Expect = 1e-43 Identities = 305/1609 (18%), Positives = 696/1609 (43%), Gaps = 171/1609 (10%) Query: 49 ERQIKFERAQKCLENAALVSKRIKEHRKATAELLGRPFVPGISESLANTLKQKEILMEKI 108 E+ I+ + + +N L S++I E ++ ELL R E N ++Q + + Sbjct: 1285 EQIIELKEEIRQQQNKYLESQKINEKKQKEIELLRREV-----EEFQNEIQQLTQRNQSL 1339 Query: 109 KQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNALSVLQVKMKIM 168 + + + + S+ E + L + +++++ Sbjct: 1340 NSRLQAQNQEINLLKNEKEEYNLLKHDQINENSSNQDRNSSESNEGTSDLELARMQIEGQ 1399 Query: 169 ETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQEN---- 224 E + LQ + KD I+ N+ E Q ++++EN Sbjct: 1400 ERDLEKLQIDLRTKDSYIDEMNQENLMLKDKVNQQQQEIRYLQEQVSQLNSEIEENVQRQ 1459 Query: 225 --FIAME-AEWKDEKQRLLKDIESKDVRISSLE----EANKLLEAARFEISL---EHSKL 274 I M+ +++E++++ K +E + L + + + +A +I E+ K Sbjct: 1460 DELIEMQKVNFENEREQMQKVLEENLEELKRLRNERGQTSDQVHSASKQIQFWQQEYEKA 1519 Query: 275 AQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHL 334 QE E+ + +S S + + +IE + + + + ++++ E + Sbjct: 1520 QQECEKVLSDFNLLQREFQKIQAESDLKSAKLQKQIERQSRV----IFDQEQQLQQSERM 1575 Query: 335 NCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETL 394 N R ++K+ E++L +S +SP ++ ++ N + + QL +E Sbjct: 1576 NSSRRFSSKK-EDQL----NQSSLSNSPEREWQKKYNQLKEEN--EQFSRDYQQLINE-- 1626 Query: 395 NQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQL 454 NQ +++ K E + L++ + N +L ++ + E ++ + +A++Q Sbjct: 1627 NQRILEEVRKLEESCLQL--KERNSELDEENSSLREDNSALMQQVQQIKSQ---VAEIQQ 1681 Query: 455 EHQQHMEGPS---LIHVGTNTE-DVNEIA--KVQEQLKQELNDEIKDVNVKDLI-EKLKS 507 +++Q E S +++ GT E V++ +VQ++L+Q I N ++ E++K Sbjct: 1682 QYEQQAEKESEYEMLYKGTQDELQVSKTINKQVQDKLRQVQQSLIDKENYCSILQEQIKE 1741 Query: 508 AEEQITQLNDEIDAANKNMIKVKSNHKLKLKQ-------MQKTIDNF------------S 548 + ++ D+ D KN+ K K++ + LKQ M++ ++N S Sbjct: 1742 YNGVLQKMKDDEDNVEKNL-KEKTSEIIDLKQQMNLYIEMKQEMENQYKSKDEQLDVAES 1800 Query: 549 KVSDSNKEIVRLTEELHHLSQKVAELEE---EKGNLQLHLVDYDSGRMIE-SDVYKKMIE 604 K+ ++ KE ++L +E+ LSQ + E+ ++ QL+ ++ + +I+ +D + I+ Sbjct: 1801 KLREAQKENLKLKQEVQKLSQSGNQQEDMLNQQDQQQLNTLEQEKQSLIDQNDQLRDQIQ 1860 Query: 605 MENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHL 664 N I L Q FD ++ L + +E + + D+ DQ+ S+I+ L Sbjct: 1861 QLN------SQIQDLSKQNFDFDNQIEDLNNRIEEKDRDIQDLQNRIGDQL-SQIQ--RL 1911 Query: 665 EEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKL 724 +E + +++ + I++++++K+Q I+ LE E + +++ N +Q +D+ ++ Sbjct: 1912 KEDL----TQEEQKNVQIQSIQIEKDQ---KIQVLEEQAESLTDEITN-LQGQIDILNRQ 1963 Query: 725 EKMSAEKISELLAK----INHEEQSKIQTQFGIDAKIQERDLYIEN--IESELSKYKSRI 778 S +SE+ +N +++ + Q D + Q L IEN ++ ELS+ KS Sbjct: 1964 LNSSYNTLSEIQKNKQTFVNQDKELEKFQQIQADQQKQIDSLLIENEKLQQELSQQKSDF 2023 Query: 779 CRLEESIAVMEDRRYSL----ERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHD 834 EES ++ + L + K +QL +YL+EK + + ++E RL + Sbjct: 2024 ---EESQKMLNQQTVQLSEQAQHKQEQLKNYLEEKNTILVDNSNLKEE-TERLQQDLQKQ 2079 Query: 835 RVV----EKQLLEIEHE----NKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRT 886 ++ E++++ +E ++LQ+K +IL + + +Q+ + +++Q L++ + Sbjct: 2080 FIITARNEEKIIFLEQSMEQLKQDLQQKEEILESKEEIIQLKIEEIKQLEGKLLQHEEKI 2139 Query: 887 -----DLAESE--STKYQTQLRDLESNLKRITHEHQTLI---VQKKKEIEDLEI------ 930 D+ + E S + +++ LE ++ + Q L+ + + E L+I Sbjct: 2140 HQLQDDIWQKEENSQLLEEKIQQLEEKIQEYEEKIQNLVEDNISQNISQEQLQIQQKIID 2199 Query: 931 EFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELID 990 E+ ++++++ L ++ + + LE QL E + E L N +E+ + LID Sbjct: 2200 EYTQKLDASLEKAGELQKQITFKQQKIAILEKQLNEVEAENELLKQN-QEVREQEFALID 2258 Query: 991 KHVQ--KQQTQ------------SPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQ 1036 + ++ K+Q Q S + EQ ++ +++ ++++ +LNQ+ +Q Sbjct: 2259 EQIKSHKEQIQNLKNQLQVSESKSKEKLEQNSDQKRNQQKKIEEYEQKLESLNQQFLQSQ 2318 Query: 1037 VSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELK 1096 Y ++ +L Q K + + E + + K + D + + ++L LV EQ D+I EL Sbjct: 2319 NQYEDQINQCNQQLIQARNKEKQLNETISQNEKTIDDLRINIKDLNNLVYEQIDKINELT 2378 Query: 1097 ETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEF-IQERS 1155 E +L E ++ + + + + + LK ++E E I + Sbjct: 2379 E-QLNQEREQFNSD---LQKEVLAKQEQESEFNSIKQQLHEQNDTLKKEKEREIQILKDQ 2434 Query: 1156 VLQEQSAKLNTELQECYTKIIQLETLNTELTGH-DVVNQEQINQLKSKLEQLNTENDNLL 1214 + + K N EL + ++ L ++ H D++N+ + Q ++K+ Q + + Sbjct: 2435 IEHLEKEKNNLELNIEKQREEEMSMLRAQIASHKDIINE--LRQERTKISQSDQSKAEEI 2492 Query: 1215 STVAELRSSISSAVDQRGFEIAELW-KQHLAQREA-DFQKTEHELRVQLSAFESKYEQLL 1272 + + + I D+ + +L K + Q E + K +E+ ++ E ++ Sbjct: 2493 QKLEQQLNQIKYDKDELQENVNQLQNKIDINQNEKNEISKMLNEVTLEKERKEKDFKNKE 2552 Query: 1273 DSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVIN----QIEILRSEIE 1328 +++ EE K++ LQ KL+ + + NL++ AD+ + +I I+R ++ Sbjct: 2553 ETLNQQLNEENRKVL------QLQEKLEKHQTEIANLRQNLADLSSSSQEEINIIREQLN 2606 Query: 1329 DEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXX 1388 + +A +++ S +EQ I+++ +N +L Sbjct: 2607 SQVIASNNNIQMLQDQIKQYQQKSQSDADSQILQREQKIVDLVNQNTELNNQLHEANTKI 2666 Query: 1389 XXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRI 1448 + +A++ E + LK+S++ ++ + Q F++ + L + + ++ Sbjct: 2667 SQLNAKNQQEKARLEE---SITLKESQLEEQKEQQN----QLKLSFQHEKSILEKEKDQL 2719 Query: 1449 EDLTYEKESELAILRLKMHE-NANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAE 1507 ++ E++ L K E N E +K S+ + +++ N K+ ES+ K+ + Sbjct: 2720 LQQISQQNDEISSLTQKETEFNEQKSEYQEKISKFKAQ--LDQTNAKLEESL---KEQSN 2774 Query: 1508 LNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQK 1556 L + + + +N+ T +E+ + E+ LN+ I + +IQK Sbjct: 2775 LKQQISLQNENSNQQNTKIEDLQTEVEQLNNLIKQINQKYLDLQHEIQK 2823 Score = 177 bits (431), Expect = 2e-42 Identities = 278/1484 (18%), Positives = 627/1484 (42%), Gaps = 123/1484 (8%) Query: 153 EKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXE 212 E D + LQ +++ I D ++++ + +++ ++ ++ Sbjct: 1543 ESDLKSAKLQKQIERQSRVIFDQEQQLQQSERMNSSRRFSSKKEDQLNQSSLSNSPEREW 1602 Query: 213 DTK-QQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271 K Q+ + E F + +E QR+L+++ + L+E N L+ + ++ Sbjct: 1603 QKKYNQLKEENEQFSRDYQQLINENQRILEEVRKLEESCLQLKERNSELDEENSSLREDN 1662 Query: 272 SKLAQELEQXXXXXXXXXXXXXXLAKQSIE-----PSCEEKTEIEEKGSLEIANMTELTK 326 S L Q+++Q A++ E +++ ++ + + ++ + + Sbjct: 1663 SALMQQVQQIKSQVAEIQQQYEQQAEKESEYEMLYKGTQDELQVSKTINKQVQDKLRQVQ 1722 Query: 327 KIELLEHLNCQIRQTN-KELENKLATMGTESKAVSSPSK-KGSPLISRKSGRNTASKMKS 384 + + + C I Q KE L M + V K K S +I K N +MK Sbjct: 1723 QSLIDKENYCSILQEQIKEYNGVLQKMKDDEDNVEKNLKEKTSEIIDLKQQMNLYIEMKQ 1782 Query: 385 PW-SQLSSETLNQD-TDKKIN--KNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXX 440 +Q S+ D + K+ + E KL+ +Q L++ +E +++++D Sbjct: 1783 EMENQYKSKDEQLDVAESKLREAQKENLKLKQEVQKLSQSGNQQEDMLNQQDQQQLNTLE 1842 Query: 441 XXXGKDTLIAQL-QLEHQQHMEGPSLIHVGTNTEDV-NEIAKVQEQLKQELNDEIKDVNV 498 K +LI Q QL Q + + D N+I + ++++ KD ++ Sbjct: 1843 QE--KQSLIDQNDQLRDQIQQLNSQIQDLSKQNFDFDNQIEDLNNRIEE------KDRDI 1894 Query: 499 KDLIEKLKSAEEQITQLNDEIDAANKNMIKVKS---NHKLKLKQMQKTIDNFS-KVSDSN 554 +DL ++ QI +L +++ + ++++S K++ +++ ++ + ++++ Sbjct: 1895 QDLQNRIGDQLSQIQRLKEDLTQEEQKNVQIQSIQIEKDQKIQVLEEQAESLTDEITNLQ 1954 Query: 555 KEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLK 614 +I L +L+ ++E+++ K + + + I++D K ++++L K Sbjct: 1955 GQIDILNRQLNSSYNTLSEIQKNKQTFVNQDKELEKFQQIQADQQK---QIDSLLIENEK 2011 Query: 615 AISLLESQKFDLVQELHILQQK----YDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDA 670 L QK D + +L Q+ ++ + K + ++ + + +L+E+ + Sbjct: 2012 LQQELSQQKSDFEESQKMLNQQTVQLSEQAQHKQEQLKNYLEEKNTILVDNSNLKEETER 2071 Query: 671 LSAS-KKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSA 729 L +K+ + N +E++ + +E K+D+ K +E ++ +++ ++ Sbjct: 2072 LQQDLQKQFIITARN----EEKIIFLEQSMEQLKQDLQQK-----EEILESKEEIIQLKI 2122 Query: 730 EKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVME 789 E+I +L K+ E+ Q Q I K + L +E ++ + + +I EE I + Sbjct: 2123 EEIKQLEGKLLQHEEKIHQLQDDIWQKEENSQL----LEEKIQQLEEKIQEYEEKIQNLV 2178 Query: 790 DRRYSLERKADQLGSYLQEKQKAYSEYTIQED-------ELVNRLAVLMDHDRVVEKQLL 842 + S +Q LQ +QK EYT + D EL ++ ++EKQL Sbjct: 2179 EDNISQNISQEQ----LQIQQKIIDEYTQKLDASLEKAGELQKQITFKQQKIAILEKQLN 2234 Query: 843 EIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRD 902 E+E EN EL K+NQ + E Q + ++ H + N+ ++ES+S + Q D Sbjct: 2235 EVEAEN-ELLKQNQEVRE--QEFALIDEQIKSHKEQIQNLKNQLQVSESKSKEKLEQNSD 2291 Query: 903 LESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEA 962 + N ++ E++ QK + + ++ Q E I N++ + QL Sbjct: 2292 QKRNQQKKIEEYE----QKLESLNQQFLQSQNQYEDQINQ---CNQQLIQARNKEKQLNE 2344 Query: 963 QLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKD 1022 + + + I++L +N+++LN + E IDK + + Q EQ+ +++ K L KQ+ Sbjct: 2345 TISQNEKTIDDLRINIKDLNNLVYEQIDK-INELTEQLNQEREQFNSDLQK-EVLAKQEQ 2402 Query: 1023 E-EIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEEL 1081 E E ++ Q+++ ++ + E ++ ++E++E+E + +L KQ EE+ Sbjct: 2403 ESEFNSIKQQLHEQN---DTLKKEKEREIQILKDQIEHLEKEKNNL--ELNIEKQREEEM 2457 Query: 1082 QIL---VREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXX 1138 +L + D I EL++ + + +++ I + ++ + D Sbjct: 2458 SMLRAQIASHKDIINELRQERTKISQS-DQSKAEEIQKLEQQLNQIKYDKDELQENVNQL 2516 Query: 1139 XXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQ 1198 + + + E+ E S + + L E +E K + ETLN +L + ++ Q Sbjct: 2517 QNKIDINQNEK--NEISKMLNE-VTLEKERKEKDFKNKE-ETLNQQLNEEN----RKVLQ 2568 Query: 1199 LKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELR 1258 L+ KLE+ TE NL +A+L SS ++ + ++ L + L+ Sbjct: 2569 LQEKLEKHQTEIANLRQNLADLSSSSQEEIN--------IIREQLNSQVIASNNNIQMLQ 2620 Query: 1259 VQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNL----QEKYA 1314 Q+ ++ K + DS Q E + + Q T L N+L + + L Q++ A Sbjct: 2621 DQIKQYQQKSQSDADS--QILQREQKIVDLVNQNTELNNQLHEANTKISQLNAKNQQEKA 2678 Query: 1315 DVINQIEILRSEIEDE-------KVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSI 1367 + I + S++E++ K++F + +N + ++ Sbjct: 2679 RLEESITLKESQLEEQKEQQNQLKLSFQHEKSILEKEKDQLLQQISQQNDEISSLTQKE- 2737 Query: 1368 LNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQ---KTHEYT 1424 NE+ ++ ++ ++ ++ + L Q+ L++ Q K + Sbjct: 2738 TEFNEQKSEYQEKISKFKAQLDQTNAKLEESLKEQSNLKQQISLQNENSNQQNTKIEDLQ 2797 Query: 1425 ITLTQRNDEFENVRQQLVEYEKRIEDLTYEK---ESELAILRLKMHENANHYETMQKESE 1481 + Q N+ + + Q+ ++ + I+ +EK + E+ + YE Q + E Sbjct: 2798 TEVEQLNNLIKQINQKYLDLQHEIQKEKFEKANLQKEITHCKEDYQIVQQKYENFQAQHE 2857 Query: 1482 IERVKLIEELNVKITESVSLNKQVAE--LNKALEEEVAKTNEMQTALENQEIEIVTLNDE 1539 +++KLI+ + + ES L KQ + K ++ + ++ + ++ ++ +I L DE Sbjct: 2858 -DQLKLIKSTHAQ--ESAHLKKQYQQEFQQKLIDTQKDLQSKHEVEIKQKDEQISKLQDE 2914 Query: 1540 ITNLQNMVRASSSKIQKHVSFASDTKQG--RDEQLDNTMNKELL 1581 +T + + I ++ + KQ +++QL+ + +LL Sbjct: 2915 LTQYKLNLEEQKQLITQNDKQVQELKQNIEQEKQLNQDLQNQLL 2958 Score = 161 bits (391), Expect = 1e-37 Identities = 277/1348 (20%), Positives = 581/1348 (43%), Gaps = 153/1348 (11%) Query: 237 QRLLKDI---ESKDVRISSLE----EANKLLEAARFEISLEHSKLAQELEQXXXXXXXXX 289 QRL +D+ E K+V+I S++ + ++LE ++ E + L +++ Sbjct: 1909 QRLKEDLTQEEQKNVQIQSIQIEKDQKIQVLEEQAESLTDEITNLQGQIDILNRQLNSSY 1968 Query: 290 XXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKL 349 + K + + E+E+ ++ ++ + E L ++ Q + E Sbjct: 1969 NTLSEIQKNK-QTFVNQDKELEKFQQIQADQQKQIDSLLIENEKLQQELSQQKSDFEESQ 2027 Query: 350 ATMGTESKAVSSPSK-KGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKI-----N 403 + ++ +S ++ K L + +NT S + +E L QD K+ N Sbjct: 2028 KMLNQQTVQLSEQAQHKQEQLKNYLEEKNTILVDNSNLKE-ETERLQQDLQKQFIITARN 2086 Query: 404 KNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGP 463 + +I LE ++ L +DL KE ++ K+ I QL++E + +EG Sbjct: 2087 EEKIIFLEQSMEQLKQDLQQKEEILESKEE---------------IIQLKIEEIKQLEGK 2131 Query: 464 SLIHVGTNTEDVNEIAKVQEQLKQ-ELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAA 522 L H +I ++Q+ + Q E N ++ + ++ L EK++ EE+I L ++ + Sbjct: 2132 LLQHE-------EKIHQLQDDIWQKEENSQLLEEKIQQLEEKIQEYEEKIQNLVEDNISQ 2184 Query: 523 NKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNL- 581 N + +++ K+ + QK + K + K+I +++ L +++ E+E E L Sbjct: 2185 NISQEQLQIQQKIIDEYTQKLDASLEKAGELQKQITFKQQKIAILEKQLNEVEAENELLK 2244 Query: 582 QLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQK-YDEV 640 Q V +I+ + +++NL + +L+ +K + + QQK +E Sbjct: 2245 QNQEVREQEFALIDEQIKSHKEQIQNL-KNQLQVSESKSKEKLEQNSDQKRNQQKKIEEY 2303 Query: 641 EDKLADISQ--LQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKD 698 E KL ++Q LQS + + ++ I A + K+ + +N K TI D Sbjct: 2304 EQKLESLNQQFLQSQNQYEDQINQCNQQLIQARNKEKQLNETISQNEK--------TIDD 2355 Query: 699 LENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHE-EQSKIQTQFGIDAKI 757 L + +D L N + E +D KI+EL ++N E EQ Q + AK Sbjct: 2356 LRINIKD----LNNLVYEQID-----------KINELTEQLNQEREQFNSDLQKEVLAK- 2399 Query: 758 QERDLYIENIESELSKYKSRICRLEE-SIAVMEDRRYSLERKADQLGSYLQEKQKAYSEY 816 QE++ +I+ +L + + + +E I +++D+ LE++ + L + EKQ+ Sbjct: 2400 QEQESEFNSIKQQLHEQNDTLKKEKEREIQILKDQIEHLEKEKNNLELNI-EKQR----- 2453 Query: 817 TIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHY 876 E+E+ A + H ++ E+ E ++ + +Q EE Q L+ L+ ++ Sbjct: 2454 ---EEEMSMLRAQIASHKDIIN----ELRQERTKISQSDQSKAEEIQKLEQQLNQIKYDK 2506 Query: 877 NALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQI 936 + L E N+ +++ Q + ++ L +T E + +K+K+ ++ E N Q+ Sbjct: 2507 DELQENVNQL---QNKIDINQNEKNEISKMLNEVTLEKE----RKEKDFKNKEETLNQQL 2559 Query: 937 ESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNI-ENLNMNVEELNKMNLELIDKHVQK 995 R L EK EK+ + L L + ++ E +N+ E+LN + + ++Q Sbjct: 2560 NEENRKVLQLQEKLEKHQTEIANLRQNLADLSSSSQEEINIIREQLNSQVIAS-NNNIQM 2618 Query: 996 QQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTT 1055 Q Q Y ++ ++ + +QK +++ N ++NN + + +K++Q Sbjct: 2619 LQDQIKQYQQKSQSDADSQILQREQKIVDLVNQNTELNN-------QLHEANTKISQLNA 2671 Query: 1056 KLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIIS 1115 K N +E+ + L Q E+ +EQ +Q+K E +I + E + Sbjct: 2672 K--NQQEKARLEESITLKESQLEEQ-----KEQQNQLK----LSFQHEKSILEKEKDQLL 2720 Query: 1116 STIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKI 1175 I +D+ +++ Q+E EF +++S QE+ +K +L + K+ Sbjct: 2721 QQISQQNDEISSL---------------TQKETEFNEQKSEYQEKISKFKAQLDQTNAKL 2765 Query: 1176 IQLETLNTELTGHDVVNQEQINQLKSKLEQLNTEND---NLLSTVAELRSSISSAVDQRG 1232 + + L + E NQ +K+E L TE + NL+ + + + + + Sbjct: 2766 EESLKEQSNLKQQISLQNENSNQQNTKIEDLQTEVEQLNNLIKQINQKYLDLQHEIQKEK 2825 Query: 1233 FEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQV 1292 FE A L K+ + + D+Q + + F++++E L ++S+ +E+ + Q Sbjct: 2826 FEKANLQKE-ITHCKEDYQIVQQ----KYENFQAQHEDQLKLIKSTHAQESAHLKKQYQ- 2879 Query: 1293 TSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDL 1352 Q KL D + ++LQ K+ I Q + S+++DE + + Sbjct: 2880 QEFQQKLIDTQ---KDLQSKHEVEIKQKDEQISKLQDELTQYKLNLEEQKQLITQNDKQV 2936 Query: 1353 RTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELK 1412 + Q+ +Q ++ LN + +N L++ +V ++++ TH + Sbjct: 2937 QELKQNIEQEKQ---LNQDLQNQLLQQEK---YLHKKIDEIQVLKKSQELIQSTHSINDH 2990 Query: 1413 DSEIYQKTHEYTITLT-QRNDEFENVRQQ----LVEYEKRIEDL--TYEKESELAILRLK 1465 ++ + ++ + T++ R + E+ R+ +++Y+K IE+L +E E L + Sbjct: 2991 NTATLRSDNDISPTMSLGRAKKVESYREDQDKIILQYKKEIENLQSLLNQEKEKCNLLNE 3050 Query: 1466 MHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTA 1525 + E + E + E+ + +I +S N+++ + N+ L+EE K E + Sbjct: 3051 EIKLKVQAEAPMQRRENNQETSAEKDHYQIL--ISQNQRLIQENQRLKEENDKLKEEYSY 3108 Query: 1526 LENQEIEIVTLNDEITNLQNMVRASSSK 1553 + + + N + QN S+SK Sbjct: 3109 YADNSVTLQQTNP--VSGQNTASQSASK 3134 Score = 154 bits (373), Expect = 2e-35 Identities = 297/1438 (20%), Positives = 604/1438 (42%), Gaps = 154/1438 (10%) Query: 212 EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEIS--- 268 +D +Q+ K Q N I + E + LK+I+S I S + +LL + + + Sbjct: 1085 KDLIKQIDKSQIN-IDQQRETISQLNFKLKEIQSNYEGIYSKLKQQELLSNQQLDENSKN 1143 Query: 269 -LEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCE---EKTEIEEKGSLEIANMTEL 324 +++ K+ E E+ Q + + + E +++++K L+ ++ + Sbjct: 1144 NMDYQKIINEYEEKLNKTQIKLNQVFDEKLQIEQNNLDTQKELSQLQQKFRLQQESLQQK 1203 Query: 325 TKKIE--------LLEHLNCQIR-QTNKELENKLATMGTESKAVSSPSKKGSPLISRKSG 375 K+IE LE L+ QI+ Q NK E + + + SS S S + Sbjct: 1204 QKEIEDEKRSFAGKLEKLDQQIQNQKNKLNEKDMTIKRLQFELQSSQSLNDSLNEIQSKQ 1263 Query: 376 RNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLE---MVIQSLN-KDLVDKEYVISEK 431 + TA + Q SE LN++ ++ K EI + + + Q +N K + E + E Sbjct: 1264 KRTAYDDRQMLKQYESEDLNEEQIIEL-KEEIRQQQNKYLESQKINEKKQKEIELLRREV 1322 Query: 432 DTXXXXXXXXXXGKDTLIAQLQLEHQQH--MEGPSLIHVGTNTEDVNEIAKVQEQLKQEL 489 + +L ++LQ ++Q+ ++ + + +NE + Q++ E Sbjct: 1323 EEFQNEIQQLTQRNQSLNSRLQAQNQEINLLKNEKEEYNLLKHDQINENSSNQDRNSSES 1382 Query: 490 NDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNM-IKVKSNHKLKLKQMQKTIDNFS 548 N+ D+ + + +++ E + +L +ID K+ I + L LK Sbjct: 1383 NEGTSDLELARM--QIEGQERDLEKL--QIDLRTKDSYIDEMNQENLMLKD--------- 1429 Query: 549 KVSDSNKEIVRLTEELHHLSQKVAELEEEKGNL-QLHLVDYDSGRMIESDVYKKMIEMEN 607 KV+ +EI L E++ L+ ++ E + + L ++ V++++ E + +K++E EN Sbjct: 1430 KVNQQQQEIRYLQEQVSQLNSEIEENVQRQDELIEMQKVNFEN----EREQMQKVLE-EN 1484 Query: 608 LAETRLKAISLLESQKFDLV----QELHILQQKYD----EVEDKLADISQLQSD----QV 655 L E LK + Q D V +++ QQ+Y+ E E L+D + LQ + Q Sbjct: 1485 LEE--LKRLRNERGQTSDQVHSASKQIQFWQQEYEKAQQECEKVLSDFNLLQREFQKIQA 1542 Query: 656 CSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQ 715 S++KS L++QI+ ++ + + +L + + + + + KED +N+ Sbjct: 1543 ESDLKSAKLQKQIE-----RQSRVIFDQEQQLQQSERMNSSRRFSSKKEDQLNQ------ 1591 Query: 716 ENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYK 775 L++ E+ +K ++L + N + Q + +I E + +E + K Sbjct: 1592 --SSLSNSPEREWQKKYNQLKEE-NEQFSRDYQQLINENQRILEE---VRKLEESCLQLK 1645 Query: 776 SRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDR 835 R L+E + + + +L ++ Q+ S + E Q+ Y + +E E D + Sbjct: 1646 ERNSELDEENSSLREDNSALMQQVQQIKSQVAEIQQQYEQQAEKESEYEMLYKGTQDELQ 1705 Query: 836 VVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKA-NRTDLAESEST 894 V + +++ + +++Q+ L + +N L + + YN +++K + D E Sbjct: 1706 VSKTINKQVQDKLRQVQQS----LIDKENYCSILQEQIKEYNGVLQKMKDDEDNVEKNLK 1761 Query: 895 KYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNI 954 + +++ DL+ + Q + Q K + E L++ ES +R+ + N K ++ + Sbjct: 1762 EKTSEIIDLKQQMNLYIEMKQEMENQYKSKDEQLDVA-----ESKLREAQKENLKLKQEV 1816 Query: 955 EYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKL 1014 + ++Q Q ++ N + +N E K +L ID Q Q D +Q ++I L Sbjct: 1817 QKLSQSGNQQEDMLNQQDQQQLNTLEQEKQSL--ID-----QNDQLRDQIQQLNSQIQDL 1869 Query: 1015 NALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDS 1074 + D +I LN +I + + +L+Q +QR+ + L Sbjct: 1870 SKQNFDFDNQIEDLNNRIEEKDRDIQDLQNRIGDQLSQ-----------IQRLKEDLTQE 1918 Query: 1075 KQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMI------ISSTIEPMSDDANNV 1128 +Q N ++Q + E+D +I+ L+E + I +G I ++S+ +S+ N Sbjct: 1919 EQKNVQIQSIQIEKDQKIQVLEEQAESLTDEITNLQGQIDILNRQLNSSYNTLSEIQKNK 1978 Query: 1129 DXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLET-LNTELTG 1187 ++Q +++ Q S+L E KL EL + + + + LN + Sbjct: 1979 QTFVNQDKELEKFQQIQADQQK-QIDSLLIENE-KLQQELSQQKSDFEESQKMLNQQTVQ 2036 Query: 1188 HDVVNQEQINQLKSKLEQLNT---ENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLA 1244 Q + QLK+ LE+ NT +N NL L+ + Q+ F I ++ + Sbjct: 2037 LSEQAQHKQEQLKNYLEEKNTILVDNSNLKEETERLQQDL-----QKQFIITARNEEKII 2091 Query: 1245 QREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEE 1304 E ++ + +L+ + ESK E + ++ Q E + E++ LQ+ + KEE Sbjct: 2092 FLEQSMEQLKQDLQQKEEILESKEEIIQLKIEEIKQLEGKLLQHEEKIHQLQDDIWQKEE 2151 Query: 1305 HLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQE 1364 + + L+EK I Q+E E E EK+ + Y Q + Sbjct: 2152 NSQLLEEK----IQQLEEKIQEYE-EKIQNLVEDNISQNISQEQLQIQQKIIDEYTQKLD 2206 Query: 1365 QSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYT 1424 S+ E+ +L+K ++N+ EA+ L E+++ E + Sbjct: 2207 ASL----EKAGELQKQITFKQQKIAILEKQLNEVEAENELLKQNQEVREQEFALIDEQ-- 2260 Query: 1425 ITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIER 1484 + ++ +N++ QL E + ++ K+ +N++ QK+ E E Sbjct: 2261 --IKSHKEQIQNLKNQLQVSESKSKE--------------KLEQNSDQKRNQQKKIE-EY 2303 Query: 1485 VKLIEELNVKITESVS-LNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNL 1543 + +E LN + +S + Q+ + N+ L + K ++ + E I L I +L Sbjct: 2304 EQKLESLNQQFLQSQNQYEDQINQCNQQLIQARNKEKQLNETISQNEKTIDDLRINIKDL 2363 Query: 1544 QNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELL-DAVPRAELDLAMYMLHQRD 1600 N+V KI + Q R EQ ++ + KE+L +E + LH+++ Sbjct: 2364 NNLVYEQIDKINE---LTEQLNQER-EQFNSDLQKEVLAKQEQESEFNSIKQQLHEQN 2417 Score = 144 bits (350), Expect = 1e-32 Identities = 273/1450 (18%), Positives = 619/1450 (42%), Gaps = 93/1450 (6%) Query: 164 KMKIMETTILDLQEKINEKDQII---EAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTK 220 K++ ++ I + + K+NEKD I + + +++ D +Q + + Sbjct: 1217 KLEKLDQQIQNQKNKLNEKDMTIKRLQFELQSSQSLNDSLNEIQSKQKRTAYDDRQMLKQ 1276 Query: 221 MQENFIAME--AEWKDE-KQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQE 277 + + E E K+E +Q+ K +ES+ + +E +LL E E +L Q Sbjct: 1277 YESEDLNEEQIIELKEEIRQQQNKYLESQKINEKKQKEI-ELLRREVEEFQNEIQQLTQR 1335 Query: 278 LEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQ 337 + L + E + + +I E S + N +E + LE Q Sbjct: 1336 NQSLNSRLQAQNQEINLLKNEKEEYNLLKHDQINENSSNQDRNSSESNEGTSDLELARMQ 1395 Query: 338 IRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASK-MKSPWSQLSSE---- 392 I ++LE + T+ + +++ L + + + + ++ SQL+SE Sbjct: 1396 IEGQERDLEKLQIDLRTKDSYIDEMNQENLMLKDKVNQQQQEIRYLQEQVSQLNSEIEEN 1455 Query: 393 TLNQD---TDKKIN-KNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTL 448 QD +K+N +NE +++ V++ ++L + Sbjct: 1456 VQRQDELIEMQKVNFENEREQMQKVLEENLEELKRLRNERGQTSDQVHSASKQIQFWQQE 1515 Query: 449 IAQLQLEHQQHMEGPSLIH---VGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKL 505 + Q E ++ + +L+ E + AK+Q+Q++++ E++ Sbjct: 1516 YEKAQQECEKVLSDFNLLQREFQKIQAESDLKSAKLQKQIERQSRVIFDQEQQLQQSERM 1575 Query: 506 KSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSK-VSDSNKEIVRLTEEL 564 S+ ++ D+++ ++ + + K K Q+++ + FS+ E R+ EE+ Sbjct: 1576 NSSRRFSSKKEDQLNQSSLSNSPEREWQK-KYNQLKEENEQFSRDYQQLINENQRILEEV 1634 Query: 565 HHLSQKVAELEEEKGNL---QLHLVDYDSGRMIESDVYKKMI-EMENLAETRLKAISLLE 620 L + +L+E L L + +S M + K + E++ E + + S E Sbjct: 1635 RKLEESCLQLKERNSELDEENSSLREDNSALMQQVQQIKSQVAEIQQQYEQQAEKESEYE 1694 Query: 621 SQKFDLVQELHILQQKYDEVEDKLADISQ--LQSDQVCSEIKSVHLEEQIDALSASKKEL 678 EL + + +V+DKL + Q + + CS I ++E L K + Sbjct: 1695 MLYKGTQDELQVSKTINKQVQDKLRQVQQSLIDKENYCS-ILQEQIKEYNGVLQKMKDDE 1753 Query: 679 ALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQ---ENMDLTD-KLEKMSAEKISE 734 V +NLK +K +K N ++ +++N + E +D+ + KL + E + + Sbjct: 1754 DNVEKNLK-EKTSEIIDLKQQMNLYIEMKQEMENQYKSKDEQLDVAESKLREAQKENL-K 1811 Query: 735 LLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESEL----SKYKSRICRLEESIAVMED 790 L ++ QS Q + ++ + Q++ +E + L + + +I +L I + Sbjct: 1812 LKQEVQKLSQSGNQQEDMLNQQDQQQLNTLEQEKQSLIDQNDQLRDQIQQLNSQIQDLSK 1871 Query: 791 RRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKE 850 + + + + + L + ++EK + + + + ++++ L + E++ ++I+ E Sbjct: 1872 QNFDFDNQIEDLNNRIEEKDRDIQDLQNRIGDQLSQIQRLKEDLTQEEQKNVQIQSIQIE 1931 Query: 851 LQKKNQILLEENQNLQISLSDMQQHYNALVEKANRT--DLAESESTK--YQTQLRDLESN 906 +K Q+L E+ ++L ++++Q + L + N + L+E + K + Q ++LE Sbjct: 1932 KDQKIQVLEEQAESLTDEITNLQGQIDILNRQLNSSYNTLSEIQKNKQTFVNQDKELE-K 1990 Query: 907 LKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQE 966 ++I + Q I E E L+ E + Q +K+LN++ + E + QL+ Sbjct: 1991 FQQIQADQQKQIDSLLIENEKLQQELSQQKSDFEESQKMLNQQTVQLSEQAQHKQEQLKN 2050 Query: 967 Y---KNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYI---NEINKLNALLKQ 1020 Y KN I N N++E E + + +QKQ + E+ I + +L L+Q Sbjct: 2051 YLEEKNTILVDNSNLKE----ETERLQQDLQKQFIITARNEEKIIFLEQSMEQLKQDLQQ 2106 Query: 1021 KDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEM--QRVSKQLLDSKQHN 1078 K EEI+ ++I ++ + E KL Q K+ +++++ + + QLL+ K Sbjct: 2107 K-EEILESKEEIIQLKI---EEIKQLEGKLLQHEEKIHQLQDDIWQKEENSQLLEEK--I 2160 Query: 1079 EELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSD--DANNVDXXXXXXX 1136 ++L+ ++E +++I+ L E ++ NI + + I I+ + DA+ Sbjct: 2161 QQLEEKIQEYEEKIQNLVEDNIS--QNISQEQLQIQQKIIDEYTQKLDASLEKAGELQKQ 2218 Query: 1137 XXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQI 1196 K+ E+ + E + + K N E++E +I + + + ++ NQ Q+ Sbjct: 2219 ITFKQQKIAILEKQLNEVEA-ENELLKQNQEVREQEFALIDEQIKSHKEQIQNLKNQLQV 2277 Query: 1197 NQLKS--KLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTE 1254 ++ KS KLEQ + + N + E + S ++Q+ + ++ + Q + Sbjct: 2278 SESKSKEKLEQNSDQKRNQQKKIEEYEQKLES-LNQQFLQSQNQYEDQINQCNQQLIQAR 2336 Query: 1255 HELRVQLSAFESKYEQLLDSVQSSTQEETNKIV-TMEQVTSLQNKL-QDKEEHLRNLQEK 1312 ++ + QL+ S+ E+ +D ++ + ++ N + ++++ L +L Q++E+ +LQ++ Sbjct: 2337 NKEK-QLNETISQNEKTIDDLRINIKDLNNLVYEQIDKINELTEQLNQEREQFNSDLQKE 2395 Query: 1313 Y---ADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYK-QMQEQSIL 1368 + ++ ++ ++ ++ L E + + +++Q Sbjct: 2396 VLAKQEQESEFNSIKQQLHEQNDTLKKEKEREIQILKDQIEHLEKEKNNLELNIEKQREE 2455 Query: 1369 NINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLT 1428 ++ AQ+ S +++ ++ E +LE + ++I E + Sbjct: 2456 EMSMLRAQI-ASHKDIINELRQERTKISQSDQSKAEEIQKLEQQLNQIKYDKDELQENVN 2514 Query: 1429 QRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLI 1488 Q ++ + + + E K + ++T EKE K + N ET+ ++ E K++ Sbjct: 2515 QLQNKIDINQNEKNEISKMLNEVTLEKER-------KEKDFKNKEETLNQQLNEENRKVL 2567 Query: 1489 ---EELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQN 1545 E+L TE +L + +A+L+ + +EE+ N ++ L +Q ++ N+ I LQ+ Sbjct: 2568 QLQEKLEKHQTEIANLRQNLADLSSSSQEEI---NIIREQLNSQ---VIASNNNIQMLQD 2621 Query: 1546 MVRASSSKIQ 1555 ++ K Q Sbjct: 2622 QIKQYQQKSQ 2631 Score = 142 bits (344), Expect = 7e-32 Identities = 211/1184 (17%), Positives = 490/1184 (41%), Gaps = 73/1184 (6%) Query: 409 KLEMVIQSLNKDLVDK-EYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIH 467 +++ +I +N +++ +Y + D ++L Q + M+ + Sbjct: 572 EIQQIISHINNQMIELIDYQATHPDVENDQEHGSVGSSNSLEGNKQDIAELRMQIEEYCN 631 Query: 468 VGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMI 527 E NE + Q LK++ ++ ++ L+ +L+ + Q+ +++ N+N Sbjct: 632 KNIMLERENEQLQEQFLLKEKETEKFIG-ELQILLNQLRIQD----QVQSDVETLNQNER 686 Query: 528 KVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGN-LQLHLV 586 + S L + + +++ +V +S K + L Q + +E N LQ +L+ Sbjct: 687 NLVS---LSISNLGESLGAIKEVVNSYKMHENQIQLLEQQLQIAIQSQENLTNQLQNNLI 743 Query: 587 DYDSGRM-IESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYD--EVEDK 643 +S + I + ++ +++L + S L+ + + + L+ + D +DK Sbjct: 744 SENSQKSEIIKQLDSQLQNLKSLLQQEQSINSDLQEENGRQRERIEQLRDQLDIFRQKDK 803 Query: 644 LADISQLQSDQVC--SEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLEN 701 + S+ D S++ S + ++Q+ ++ +IE + ++ Y +K Sbjct: 804 SSQQSKYNDDNSSQYSQLFSKYQQQQVQFNEVVRERD--IIEQKIQEMQRNYKEVKSKYE 861 Query: 702 DKEDIMNKLQNYIQENMDLTDKLEKMSA--EKISELLAKINHEEQSKIQTQFGIDAKIQE 759 +D K+Q I + +L+K S E++ L IN + I Q + Sbjct: 862 KSKDERKKMQKMISDQQQAITQLKKYSQSDEQVENLNQIINDLKNKLINQQQ--QQQQNN 919 Query: 760 RDLYIENIES---ELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEY 816 +D Y N E +L+ K R+ L+++ A +E + L + L +E K SE Sbjct: 920 KDQYSSNTEELNQDLTVIKKRMSELQQNQADLEQKNKKLYTEKKDLSKAFKEVSKLNSEL 979 Query: 817 TIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHY 876 DE + + + L + + KQ E+ N EL K+N + + +I L H Sbjct: 980 QRSNDEKIRQNSELANQISELSKQNQELSKANAELAKQNSEVTRAFKEARI-LGSSDSHK 1038 Query: 877 NALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQI 936 N + LA E+ + Q Q+RDL+ + + ++Q L++Q ++++++E I Sbjct: 1039 N-----SEGKHLA-IEAAEQQKQIRDLQKQNQELLKQNQQLLMQ----MQEVQLENKDLI 1088 Query: 937 ESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQ 996 + DK +N ++ E ++QL +L+E ++N E + +++ ++ + +D++ K Sbjct: 1089 KQI--DKSQIN--IDQQRETISQLNFKLKEIQSNYEGIYSKLKQQELLSNQQLDEN-SKN 1143 Query: 997 QTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTK 1056 +Y ++NK L Q +E + + Q + Q + + + K Sbjct: 1144 NMDYQKIINEYEEKLNKTQIKLNQVFDEKLQIEQNNLDTQKELSQLQQKFRLQQESLQQK 1203 Query: 1057 LENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISS 1116 + +E+E + + +L Q + + + E+D IK L + +L ++ + I S Sbjct: 1204 QKEIEDEKRSFAGKLEKLDQQIQNQKNKLNEKDMTIKRL-QFELQSSQSLNDSLNEIQSK 1262 Query: 1117 TIEPMSDDANNVDXXXXXXXXXXXXLKVQEE-----EEFIQERSV---LQEQSAKLNTEL 1168 DD + ++++EE ++++ + + Q++ L E+ Sbjct: 1263 QKRTAYDDRQMLKQYESEDLNEEQIIELKEEIRQQQNKYLESQKINEKKQKEIELLRREV 1322 Query: 1169 QECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAV 1228 +E +I QL N L ++IN LK++ E+ N + ++ + + SS Sbjct: 1323 EEFQNEIQQLTQRNQSLNSRLQAQNQEINLLKNEKEEYNLLKHDQINENSSNQDRNSSES 1382 Query: 1229 DQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVT 1288 ++ G EL + + +E D +K + +LR + S + ++ L Q++ Sbjct: 1383 NE-GTSDLELARMQIEGQERDLEKLQIDLRTKDSYIDEMNQENLMLKDKVNQQQQEIRYL 1441 Query: 1289 MEQVTSLQNKLQD---KEEHLRNLQE-KYADVINQIEILRSEIEDEKVAFXXXXXXXXXX 1344 EQV+ L +++++ +++ L +Q+ + + Q++ + E +E Sbjct: 1442 QEQVSQLNSEIEENVQRQDELIEMQKVNFENEREQMQKVLEENLEELKRLRNERGQTSDQ 1501 Query: 1345 XXXXXXDLRTENQSYKQMQ---EQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAK 1401 ++ Q Y++ Q E+ + + N + +K ++ Sbjct: 1502 VHSASKQIQFWQQEYEKAQQECEKVLSDFNLLQREFQKIQAESDLKSAKLQKQIERQSRV 1561 Query: 1402 VLELTHQLE----LKDSEIYQKTHEYTITLTQRND--------EFENVRQQLVEYEKRIE 1449 + + QL+ + S + E + + ++ ++ ++++ ++ + + Sbjct: 1562 IFDQEQQLQQSERMNSSRRFSSKKEDQLNQSSLSNSPEREWQKKYNQLKEENEQFSRDYQ 1621 Query: 1450 DLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELN 1509 L E + L +R K+ E+ + E + E L E+ + + + + QVAE+ Sbjct: 1622 QLINENQRILEEVR-KLEESCLQLKERNSELDEENSSLREDNSALMQQVQQIKSQVAEIQ 1680 Query: 1510 KALEEEVAKTNEMQTALENQEIEI---VTLNDEITNLQNMVRAS 1550 + E++ K +E + + + E+ T+N ++ + V+ S Sbjct: 1681 QQYEQQAEKESEYEMLYKGTQDELQVSKTINKQVQDKLRQVQQS 1724 Score = 138 bits (334), Expect = 1e-30 Identities = 233/1172 (19%), Positives = 488/1172 (41%), Gaps = 86/1172 (7%) Query: 212 EDTKQQMTKMQENFI--AMEAE----WKDEKQRLLKDIESKDVRISSLEEANKLLEAARF 265 E+T++ +Q+ FI A E + ++L +D++ K+ + S EE +++ Sbjct: 2067 EETERLQQDLQKQFIITARNEEKIIFLEQSMEQLKQDLQQKEEILESKEE---IIQLKIE 2123 Query: 266 EISLEHSKLAQELEQXXXXXXXX--XXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTE 323 EI KL Q E+ L ++ I+ E+ E EEK + + Sbjct: 2124 EIKQLEGKLLQHEEKIHQLQDDIWQKEENSQLLEEKIQQLEEKIQEYEEKIQNLVEDNIS 2183 Query: 324 LTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKM- 382 E L+ I + ++L+ L G K ++ +K + L + + +++ Sbjct: 2184 QNISQEQLQIQQKIIDEYTQKLDASLEKAGELQKQITFKQQKIAILEKQLNEVEAENELL 2243 Query: 383 KSPWSQLSSETLNQDTDKKINKNEIAKLE---MVIQSLNKDLVDK---EYVISEKDTXXX 436 K E D K +K +I L+ V +S +K+ +++ + +K Sbjct: 2244 KQNQEVREQEFALIDEQIKSHKEQIQNLKNQLQVSESKSKEKLEQNSDQKRNQQKKIEEY 2303 Query: 437 XXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDV 496 + L +Q Q E Q + LI + +NE E+ +L IKD+ Sbjct: 2304 EQKLESLNQQFLQSQNQYEDQINQCNQQLIQARNKEKQLNETISQNEKTIDDLRINIKDL 2363 Query: 497 N--VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTI--DNFSKVSD 552 N V + I+K+ EQ+ Q ++ ++ + + K + + +++ + N + + Sbjct: 2364 NNLVYEQIDKINELTEQLNQEREQFNSDLQKEVLAKQEQESEFNSIKQQLHEQNDTLKKE 2423 Query: 553 SNKEIVRLTEELHHLSQKVAELE-----EEKGNLQLHLVDYDSGRMIESDVYKKMIEMEN 607 +EI L +++ HL ++ LE + + + + S + I +++ ++ ++ Sbjct: 2424 KEREIQILKDQIEHLEKEKNNLELNIEKQREEEMSMLRAQIASHKDIINELRQERTKISQ 2483 Query: 608 LAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQ 667 +++ + I LE Q + + LQ+ +++++K+ DI+Q + +++ + V LE++ Sbjct: 2484 SDQSKAEEIQKLEQQLNQIKYDKDELQENVNQLQNKI-DINQNEKNEISKMLNEVTLEKE 2542 Query: 668 IDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKM 727 KE L + L + ++ + LE + +I N QN + +++ + Sbjct: 2543 RKEKDFKNKEETLN-QQLNEENRKVLQLQEKLEKHQTEIANLRQNLADLSSSSQEEINII 2601 Query: 728 SAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAV 787 + S+++A N+ + + Q + + D I E ++ ++ L + Sbjct: 2602 REQLNSQVIASNNNIQMLQDQIKQYQQKSQSDADSQILQREQKIVDLVNQNTELNNQLHE 2661 Query: 788 MEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDR-VVEKQ----LL 842 + L K Q + L+E ++ E N+L + H++ ++EK+ L Sbjct: 2662 ANTKISQLNAKNQQEKARLEESITLKESQLEEQKEQQNQLKLSFQHEKSILEKEKDQLLQ 2721 Query: 843 EIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRD 902 +I +N E+ Q E N+ S+ Q+ + + ++T+ ES K Q+ L+ Sbjct: 2722 QISQQNDEISSLTQKETEFNEQK----SEYQEKISKFKAQLDQTNAKLEESLKEQSNLKQ 2777 Query: 903 LESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRD--KKVLNEKYEK-NIEY-VT 958 S +++ T I + E+E L QI D ++ EK+EK N++ +T Sbjct: 2778 QISLQNENSNQQNTKIEDLQTEVEQLN-NLIKQINQKYLDLQHEIQKEKFEKANLQKEIT 2836 Query: 959 QLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALL 1018 + Q + EN E+ K+ + H Q+ Y +++ ++ L Sbjct: 2837 HCKEDYQIVQQKYENFQAQHEDQLKL---IKSTHAQESAHLKKQYQQEFQQKLIDTQKDL 2893 Query: 1019 KQKDEEIIALNQKINNAQVSYMS-MVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQH 1077 + K E + + QK + Q+S + ++ Y+ L + + ++++Q + + + KQ Sbjct: 2894 QSKHE--VEIKQK--DEQISKLQDELTQYKLNLEEQKQLITQNDKQVQELKQNIEQEKQL 2949 Query: 1078 NEELQILVREQD-------DQIKELKETK----LTFEMNIPKTEGMIISSTIEPMSDDAN 1126 N++LQ + +Q+ D+I+ LK+++ T +N T + + I P Sbjct: 2950 NQDLQNQLLQQEKYLHKKIDEIQVLKKSQELIQSTHSINDHNTATLRSDNDISPTMSLGR 3009 Query: 1127 NVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKI-----IQLETL 1181 L+ ++E E +Q S+L ++ K N +E K+ +Q Sbjct: 3010 AKKVESYREDQDKIILQYKKEIENLQ--SLLNQEKEKCNLLNEEIKLKVQAEAPMQRREN 3067 Query: 1182 NTELTG---HDVVNQEQINQLKSKLEQLNTENDNL---LSTVAELRSSISSAVDQRGFEI 1235 N E + H + Q +L + ++L END L S A+ ++ G Sbjct: 3068 NQETSAEKDHYQILISQNQRLIQENQRLKEENDKLKEEYSYYADNSVTLQQTNPVSGQNT 3127 Query: 1236 AELWKQHLAQREADFQKTEHELRVQL--SAFESKYEQL-------LDSVQSSTQEETNKI 1286 A AQ + Q T+ EL+VQ+ + EQ+ L+ +Q Q+E Sbjct: 3128 ASQSASKPAQ-DLQTQNTDIELQVQILQEQISKQNEQIVKNEQNILEFIQQKEQQEQQYH 3186 Query: 1287 VTMEQVTSLQNKLQDKEEHLRNLQEKYADVIN 1318 + + +++NKL +KE +R LQ+ YAD ++ Sbjct: 3187 NLLIEFNNVKNKLIEKENEIRFLQQ-YADKLS 3217 Score = 124 bits (300), Expect = 2e-26 Identities = 253/1246 (20%), Positives = 536/1246 (43%), Gaps = 141/1246 (11%) Query: 144 VTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXX 203 + L+N I+EKD + LQ ++ + I L+E + +++Q KN Sbjct: 1880 IEDLNNRIEEKDRDIQDLQNRIGDQLSQIQRLKEDLTQEEQ----KNVQIQSIQIEKDQK 1935 Query: 204 XXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAA 263 E ++T +Q + + L + ++K ++ +E K + Sbjct: 1936 IQVLEEQAESLTDEITNLQGQIDILNRQLNSSYNTLSEIQKNKQTFVNQDKELEKFQQIQ 1995 Query: 264 RFE------ISLEHSKLAQELEQXXX----XXXXXXXXXXXLAKQSIEPSCEEKTEIEEK 313 + + +E+ KL QEL Q L++Q+ + K +EEK Sbjct: 1996 ADQQKQIDSLLIENEKLQQELSQQKSDFEESQKMLNQQTVQLSEQAQHKQEQLKNYLEEK 2055 Query: 314 GSLEI--ANMTELTKKIELLEHLNCQIRQTNKE----LENKLATM--GTESKAVSSPSKK 365 ++ + +N+ E T++++ I N+E LE + + + K SK+ Sbjct: 2056 NTILVDNSNLKEETERLQQDLQKQFIITARNEEKIIFLEQSMEQLKQDLQQKEEILESKE 2115 Query: 366 GSPLISRKSGRNTASKM---KSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLV 422 + + + K+ + QL + ++ + ++ + +I +LE IQ + + Sbjct: 2116 EIIQLKIEEIKQLEGKLLQHEEKIHQLQDDIWQKEENSQLLEEKIQQLEEKIQEYEEKIQ 2175 Query: 423 D--KEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLI---HVGTNTEDVNE 477 + ++ + + T LE ++ + + +NE Sbjct: 2176 NLVEDNISQNISQEQLQIQQKIIDEYTQKLDASLEKAGELQKQITFKQQKIAILEKQLNE 2235 Query: 478 IAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAA-NKNMIKVKSNHKLK 536 + E LKQ N E+++ + E++KS +EQI L +++ + +K+ K++ N K Sbjct: 2236 VEAENELLKQ--NQEVREQEFALIDEQIKSHKEQIQNLKNQLQVSESKSKEKLEQNSDQK 2293 Query: 537 LKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIES 596 Q +K + K+ N++ ++ SQ E + + N QL + + + + Sbjct: 2294 RNQQKKIEEYEQKLESLNQQFLQ--------SQNQYEDQINQCNQQL-IQARNKEKQLNE 2344 Query: 597 DVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQ--LQSDQ 654 + + +++L +K ++ L ++ D + EL +Q E E +D+ + L + Sbjct: 2345 TISQNEKTIDDL-RINIKDLNNLVYEQIDKINEL--TEQLNQEREQFNSDLQKEVLAKQE 2401 Query: 655 VCSEIKSV--HLEEQIDALSASK-KELALV---IENLKLDKEQLYGTIKDLENDKEDIMN 708 SE S+ L EQ D L K +E+ ++ IE+L+ +K L ++E +E+ M+ Sbjct: 2402 QESEFNSIKQQLHEQNDTLKKEKEREIQILKDQIEHLEKEKNNLE---LNIEKQREEEMS 2458 Query: 709 KLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIE 768 L+ I + D+ ++L + E+ KI+ +QSK + +IQ+ + + I+ Sbjct: 2459 MLRAQIASHKDIINELRQ---ER-----TKISQSDQSKAE-------EIQKLEQQLNQIK 2503 Query: 769 SELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLA 828 + + + + +L+ I + ++ + + + L EK++ ++ +E+ L +L Sbjct: 2504 YDKDELQENVNQLQNKIDINQNEKNEISK---MLNEVTLEKERKEKDFKNKEETLNQQL- 2559 Query: 829 VLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDL 888 +++L+++ ++L+K + QNL S Q+ N + E+ N + Sbjct: 2560 ------NEENRKVLQLQ---EKLEKHQTEIANLRQNLADLSSSSQEEINIIREQLNSQVI 2610 Query: 889 AESESTK-YQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLN 947 A + + + Q Q++ + ++ + + I+Q++++I DL + NT++ N Sbjct: 2611 ASNNNIQMLQDQIKQYQ---QKSQSDADSQILQREQKIVDL-VNQNTELN---------N 2657 Query: 948 EKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQY 1007 + +E N + ++QL A+ Q+ K +E E + +L ++ Q+ Q + E+ Sbjct: 2658 QLHEANTK-ISQLNAKNQQEKARLE------ESITLKESQLEEQKEQQNQLKLSFQHEKS 2710 Query: 1008 INEINKLNAL--LKQKDEEIIALNQK---INNAQVSYMSMVSDYESKLAQFTTKLENMEE 1062 I E K L + Q+++EI +L QK N + Y +S ++++L Q KLE + Sbjct: 2711 ILEKEKDQLLQQISQQNDEISSLTQKETEFNEQKSEYQEKISKFKAQLDQTNAKLEESLK 2770 Query: 1063 EM----QRVSKQLLDSKQHN---EELQILVREQDDQIKELKETKLTFEMNIPKT--EGMI 1113 E Q++S Q +S Q N E+LQ V + ++ IK++ + L + I K E Sbjct: 2771 EQSNLKQQISLQNENSNQQNTKIEDLQTEVEQLNNLIKQINQKYLDLQHEIQKEKFEKAN 2830 Query: 1114 ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYT 1173 + I +D V + Q E++ +S ++SA L + Q+ + Sbjct: 2831 LQKEITHCKEDYQIVQ-------QKYENFQAQHEDQLKLIKSTHAQESAHLKKQYQQEFQ 2883 Query: 1174 KIIQLETLNTELTGHDV-VNQ--EQINQLKSKLEQ--LNTENDNLLSTVAELR-SSISSA 1227 + + ++T + H+V + Q EQI++L+ +L Q LN E L T + + + Sbjct: 2884 QKL-IDTQKDLQSKHEVEIKQKDEQISKLQDELTQYKLNLEEQKQLITQNDKQVQELKQN 2942 Query: 1228 VDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIV 1287 ++Q ++ + + L Q+E K E++V K ++L+ S S T + Sbjct: 2943 IEQEK-QLNQDLQNQLLQQEKYLHKKIDEIQVL-----KKSQELIQSTHSINDHNTATLR 2996 Query: 1288 TMEQVTSLQNKLQDKE-EHLRNLQEK-YADVINQIEILRSEIEDEK 1331 + ++ + + K+ E R Q+K +IE L+S + EK Sbjct: 2997 SDNDISPTMSLGRAKKVESYREDQDKIILQYKKEIENLQSLLNQEK 3042 Score = 120 bits (289), Expect = 3e-25 Identities = 201/1083 (18%), Positives = 467/1083 (43%), Gaps = 98/1083 (9%) Query: 504 KLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEE 563 K+ +E IT + + + + KL Q + + + +K+ E+ L + Sbjct: 322 KILKDKEAITMQTEYQMSQKEEEVNYLKEQIQKLMQESRNVLHENKILSDENEV--LQTK 379 Query: 564 LHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAIS-LLESQ 622 + L K+AE+E++ + + L S + D K + N + + ++ Sbjct: 380 IKTLKAKLAEVEKKSADRKASLKQVYSILQQKDDQIKMLQANNNNNNNNMNNFNNAIQQN 439 Query: 623 KFDLVQELH--ILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELAL 680 L + I+ Q D+ +LA++ + +Q ++V+ + I A L Sbjct: 440 SASLAAASNSIIINQIKDDFARQLAEVEKSFLNQFHQIERAVNQKNDIIA------NLED 493 Query: 681 VIENLKLDKEQLYGTIK-DLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKI 739 I+NL L K + K DL + E ++ + +N + ++ + + A+K+ +L AK Sbjct: 494 QIKNLNLSKRNITSNNKIDLSSPIEFTLSNNTSKRNQNANTVNQEQLIRAKKM-DLEAK- 551 Query: 740 NHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKA 799 E Q + Q+R + I+ +S +++ L + A D E + Sbjct: 552 --RENLVDIIQNNPNLPTQKR----QEIQQIISHINNQMIELIDYQATHPDVENDQEHGS 605 Query: 800 DQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILL 859 + L+ ++ +E +Q +E N+ +L + +++Q L E E ++ + QILL Sbjct: 606 VGSSNSLEGNKQDIAELRMQIEEYCNKNIMLERENEQLQEQFLLKEKETEKFIGELQILL 665 Query: 860 EE---NQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQT 916 + +Q + + Q+ LV + ++L ES ++++ ++ K HE+Q Sbjct: 666 NQLRIQDQVQSDVETLNQNERNLV-SLSISNLGESLGA-----IKEVVNSYK--MHENQI 717 Query: 917 LIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNI---EN 973 +++++ +I I+ + + +++ +++E +K+ E + QL++QLQ K+ + ++ Sbjct: 718 QLLEQQLQI---AIQSQENLTNQLQN-NLISENSQKS-EIIKQLDSQLQNLKSLLQQEQS 772 Query: 974 LNMNVEELNKMNLELIDK-----HVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIAL 1028 +N +++E N E I++ + +Q+ +S ++ + ++ + L + ++ + Sbjct: 773 INSDLQEENGRQRERIEQLRDQLDIFRQKDKSSQQSKYNDDNSSQYSQLFSKYQQQQVQF 832 Query: 1029 NQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQ 1088 N+ + + + + + + +K E ++E +++ K + D +Q +L+ + Sbjct: 833 NEVVRERDI-IEQKIQEMQRNYKEVKSKYEKSKDERKKMQKMISDQQQAITQLK-KYSQS 890 Query: 1089 DDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKV--QE 1146 D+Q++ L + I + +I+ + NN D L V + Sbjct: 891 DEQVENLNQI-------INDLKNKLIN---QQQQQQQNNKDQYSSNTEELNQDLTVIKKR 940 Query: 1147 EEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQL 1206 E Q ++ L++++ KL TE ++ ++ LN+EL + Q ++L +++ +L Sbjct: 941 MSELQQNQADLEQKNKKLYTEKKDLSKAFKEVSKLNSELQRSNDEKIRQNSELANQISEL 1000 Query: 1207 NTENDNLLSTVAELRSSISSAVDQRGFEIAELW----------KQHLAQREADFQKTEHE 1256 + +N L AEL S R F+ A + +HLA A+ QK + Sbjct: 1001 SKQNQELSKANAELAKQNSEVT--RAFKEARILGSSDSHKNSEGKHLAIEAAEQQKQIRD 1058 Query: 1257 LRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADV 1316 L+ Q + +QLL +Q E + I +Q+ Q + + E + L K ++ Sbjct: 1059 LQKQNQELLKQNQQLLMQMQEVQLENKDLI---KQIDKSQINIDQQRETISQLNFKLKEI 1115 Query: 1317 INQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNIN---EE 1373 + E + S+++ +++ D + Y++ ++ + +N +E Sbjct: 1116 QSNYEGIYSKLKQQEL----LSNQQLDENSKNNMDYQKIINEYEEKLNKTQIKLNQVFDE 1171 Query: 1374 NAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDE 1433 Q+++++ ++ + K L+ K EI + + L + + + Sbjct: 1172 KLQIEQNN-------LDTQKELSQLQQKFRLQQESLQQKQKEIEDEKRSFAGKLEKLDQQ 1224 Query: 1434 FENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNV 1493 +N + +L E + I+ L +E +S + ++++ N ++ QK + + +++++ Sbjct: 1225 IQNQKNKLNEKDMTIKRLQFELQSSQS-----LNDSLNEIQSKQKRTAYDDRQMLKQY-- 1277 Query: 1494 KITESVSLN-KQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSS 1552 ES LN +Q+ EL + + ++ K E Q E ++ EI L E+ QN ++ + Sbjct: 1278 ---ESEDLNEEQIIELKEEIRQQQNKYLESQKINEKKQKEIELLRREVEEFQNEIQQLTQ 1334 Query: 1553 KIQ 1555 + Q Sbjct: 1335 RNQ 1337 Score = 94.3 bits (224), Expect = 2e-17 Identities = 241/1215 (19%), Positives = 489/1215 (40%), Gaps = 101/1215 (8%) Query: 62 ENAALVSKRIKEHRKATAELLG-RPFVPGISESLANTLKQKEILMEKIKQYKELSKRSST 120 E +++ +I H+ EL R + +S A +++ E + +IK K+ + + Sbjct: 2455 EEMSMLRAQIASHKDIINELRQERTKISQSDQSKAEEIQKLEQQLNQIKYDKD-ELQENV 2513 Query: 121 TIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKD--NALSVLQVKMKIMETTILDLQEK 178 ++ L +VT L KEKD N L ++ +L LQEK Sbjct: 2514 NQLQNKIDINQNEKNEISKMLNEVT-LEKERKEKDFKNKEETLNQQLNEENRKVLQLQEK 2572 Query: 179 INEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQR 238 + EK Q A + E Q+ N ++ + K +Q+ Sbjct: 2573 L-EKHQTEIANLRQNLADLSSSSQEEINIIR--EQLNSQVIASNNNIQMLQDQIKQYQQK 2629 Query: 239 LLKDIES----KDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXX 294 D +S ++ +I L N L E + + S+L + +Q Sbjct: 2630 SQSDADSQILQREQKIVDLVNQNTELNNQLHEANTKISQLNAKNQQEKARLEESITLKES 2689 Query: 295 LAKQSIEPSCEEKTEIE-EKGSLEIANMTELTKKIELLEHLNCQIRQ-TNKELENKLATM 352 ++ E + K + EK LE E + ++ + N +I T KE E Sbjct: 2690 QLEEQKEQQNQLKLSFQHEKSILE----KEKDQLLQQISQQNDEISSLTQKETEFNEQKS 2745 Query: 353 GTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEM 412 + K ++ + S +K S + + Q+T + + E+ +L Sbjct: 2746 EYQEKISKFKAQLDQTNAKLEESLKEQSNLKQQISLQNENSNQQNTKIEDLQTEVEQLNN 2805 Query: 413 VIQSLNKDLVDKEYVISEK--DTXXXXXXXXXXGKDTLIAQLQLEH--QQHMEGPSLIHV 468 +I+ +N+ +D ++ I ++ + +D I Q + E+ QH + LI Sbjct: 2806 LIKQINQKYLDLQHEIQKEKFEKANLQKEITHCKEDYQIVQQKYENFQAQHEDQLKLIKS 2865 Query: 469 GTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIK 528 E + + Q++ +Q+L D KD+ K +E +K +EQI++L DE+ N+ + Sbjct: 2866 THAQESAHLKKQYQQEFQQKLIDTQKDLQSKHEVE-IKQKDEQISKLQDELTQYKLNLEE 2924 Query: 529 VKSNHKLKLKQMQKTIDNFSKVSDSNKEIV-RLTEELHHLSQKVAELEEEKGNLQL---- 583 K KQ+Q+ N + N+++ +L ++ +L +K+ E++ K + +L Sbjct: 2925 QKQLITQNDKQVQELKQNIEQEKQLNQDLQNQLLQQEKYLHKKIDEIQVLKKSQELIQST 2984 Query: 584 HLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQ---ELHILQQKYDEV 640 H ++ + + SD + +L + K S E Q ++Q E+ LQ ++ Sbjct: 2985 HSINDHNTATLRSD--NDISPTMSLGRAK-KVESYREDQDKIILQYKKEIENLQSLLNQE 3041 Query: 641 EDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLE 700 ++K +++ +V +E E + + L+ +N +L +E +K+ E Sbjct: 3042 KEKCNLLNEEIKLKVQAEAPMQRRENNQETSAEKDHYQILISQNQRLIQENQ--RLKE-E 3098 Query: 701 NDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQER 760 NDK + + +Y +N + +S + + A ++ T + +I + Sbjct: 3099 NDK---LKEEYSYYADNSVTLQQTNPVSGQNTASQSASKPAQDLQTQNTDIELQVQILQE 3155 Query: 761 DLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQ------KAYS 814 + +N ++ K + I + E + ++L + + + + L EK+ + Y+ Sbjct: 3156 QISKQN--EQIVKNEQNILEFIQQKEQQEQQYHNLLIEFNNVKNKLIEKENEIRFLQQYA 3213 Query: 815 EYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLE-------ENQ-NLQ 866 + + E +++R ++Q + + +N+ ++ +N LE ENQ Sbjct: 3214 DKLSSQQEYTVYSTEGNNNNRQQQQQHIPNQLQNQNVKIRNISFLEQEGSQFEENQFEDY 3273 Query: 867 ISLSDMQQ---HYNA-LVEKANRTDLAESESTKYQ----TQLRDLESNLKRITHEHQTLI 918 I D + H +A +V N + + + + +Q + +++ R ++ Q+ I Sbjct: 3274 IHQEDAHRGSVHTSAEIVVNVNDINASNTLGRGFAQASGSQQNNQQNSNIRNSNSMQSNI 3333 Query: 919 VQ------KKKEIEDLEIEFNTQIES--AIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNN 970 +Q ++ E+ ++ N S ++ + + +K ++ +E + + E N+ Sbjct: 3334 LQGLNFNANNQQDEETNVQNNQPYNSNLSVEEGFAVLQKIDQAMEKIVW-DMDCNEELND 3392 Query: 971 IENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQ 1030 IE NL L+ + + K + E+ I KL A L++KDE+I LNQ Sbjct: 3393 IEKNQSFCSNSISQNLRLLMEKIHKSTSNRTLDNER----IEKLQAKLEEKDEQIAFLNQ 3448 Query: 1031 KINNAQ----VSYMSMVSDYESKLAQFTTKLEN----MEEEMQRVSKQLLDSKQHNEELQ 1082 K+ Q + S+V D K + N E+++Q+ S K+ + LQ Sbjct: 3449 KLQELQNVQKLLKRSIVQDINEKDPDVSRIDINPHSPKEQQIQQPSSPSASPKKSAKNLQ 3508 Query: 1083 ILVREQDDQIKELK--ETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXX 1140 L D+++ELK LT+E + + E + I ++ V Sbjct: 3509 QL----KDEVRELKYQVQDLTYERDQLELENERLQMEIRDFENEQERVQSQISLLKQEIK 3564 Query: 1141 XLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLK 1200 L+ Q I E S + +Q+ L T L + + IIQL++ TE + + +N + Sbjct: 3565 QLQSQN----IDEGSRIIKQT--LKTILPK-FLNIIQLKS-KTESQNQEAT--QYLNVML 3614 Query: 1201 SKLEQLNTENDNLLS 1215 + LE E DN++S Sbjct: 3615 NLLEFSEPEKDNIIS 3629 Score = 91.1 bits (216), Expect = 2e-16 Identities = 269/1396 (19%), Positives = 554/1396 (39%), Gaps = 161/1396 (11%) Query: 65 ALVSKRIKEHRKATAELLGRPFVPGIS--ESLANTLKQKEILMEKIKQYKELSKRSSTTI 122 AL+ ++IK H++ L + V E L QK +KI++Y++ + + Sbjct: 2255 ALIDEQIKSHKEQIQNLKNQLQVSESKSKEKLEQNSDQKRNQQKKIEEYEQKLESLNQQF 2314 Query: 123 VRXXXXXXXXXXXXXXXQL---GDVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKI 179 ++ + L+ TI + + + L++ +K + + + +KI Sbjct: 2315 LQSQNQYEDQINQCNQQLIQARNKEKQLNETISQNEKTIDDLRINIKDLNNLVYEQIDKI 2374 Query: 180 NEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAE-----WKD 234 NE + + + + KQQ+ + Q + + E E KD Sbjct: 2375 NELTEQLNQEREQFNSDLQKEVLAKQEQESEFNSIKQQLHE-QNDTLKKEKEREIQILKD 2433 Query: 235 EKQRLLKDIESKDVRISSLEEANKLLEAARF--------EISLEHSKLAQELEQXXXXXX 286 + + L K+ + ++ I E + A+ E+ E +K++Q + Sbjct: 2434 QIEHLEKEKNNLELNIEKQREEEMSMLRAQIASHKDIINELRQERTKISQSDQSKAEEIQ 2493 Query: 287 XXXXXXXXLA--KQSIEPSCEE---KTEIEEKGSLEIANM-TELTKKIELLEH------- 333 + K ++ + + K +I + EI+ M E+T + E E Sbjct: 2494 KLEQQLNQIKYDKDELQENVNQLQNKIDINQNEKNEISKMLNEVTLEKERKEKDFKNKEE 2553 Query: 334 -LNCQIRQTNK---ELENKLATMGTESKAV-------SSPSKKGSPLISRK------SGR 376 LN Q+ + N+ +L+ KL TE + SS S++ +I + + Sbjct: 2554 TLNQQLNEENRKVLQLQEKLEKHQTEIANLRQNLADLSSSSQEEINIIREQLNSQVIASN 2613 Query: 377 NTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQS--LNKDLVDKEYVISEKDTX 434 N ++ Q ++ D D +I + E +++V Q+ LN L + IS+ + Sbjct: 2614 NNIQMLQDQIKQYQQKS-QSDADSQILQREQKIVDLVNQNTELNNQLHEANTKISQLNAK 2672 Query: 435 XXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQEL---ND 491 TL + QLE Q+ + + + + + K ++QL Q++ ND Sbjct: 2673 NQQEKARLEESITL-KESQLEEQKEQQNQLKLSF---QHEKSILEKEKDQLLQQISQQND 2728 Query: 492 EIKDVNVKD--LIEKLKSAEEQITQLNDEIDAANKNM---IKVKSNHKLKLK-QMQKTID 545 EI + K+ E+ +E+I++ ++D N + +K +SN K ++ Q + + Sbjct: 2729 EISSLTQKETEFNEQKSEYQEKISKFKAQLDQTNAKLEESLKEQSNLKQQISLQNENSNQ 2788 Query: 546 NFSKVSDSNKEIVRLTEELHHLSQKVAELEEE-------KGNLQLHLVDYDSGRMIESDV 598 +K+ D E+ +L + ++QK +L+ E K NLQ + I V Sbjct: 2789 QNTKIEDLQTEVEQLNNLIKQINQKYLDLQHEIQKEKFEKANLQKEITHCKEDYQI---V 2845 Query: 599 YKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQ-LQSDQVCS 657 +K + E +LK I +Q + H+ +Q E + KL D + LQS Sbjct: 2846 QQKYENFQAQHEDQLKLIKSTHAQ-----ESAHLKKQYQQEFQQKLIDTQKDLQSKH--- 2897 Query: 658 EIKSVHLEEQIDALSASKKELALVIENLKL----DKEQLYGTIKDLENDKEDIMNKLQNY 713 E++ +EQI L + L +E K + +Q+ +++E +K+ + LQN Sbjct: 2898 EVEIKQKDEQISKLQDELTQYKLNLEEQKQLITQNDKQVQELKQNIEQEKQ-LNQDLQNQ 2956 Query: 714 I-QENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLY--IENIESE 770 + Q+ L K++++ K S+ L + H D I + +ES Sbjct: 2957 LLQQEKYLHKKIDEIQVLKKSQELIQSTHSINDHNTATLRSDNDISPTMSLGRAKKVESY 3016 Query: 771 LSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVL 830 I + ++ I ++ + K + L + K K +E +Q E + Sbjct: 3017 REDQDKIILQYKKEIENLQSLLNQEKEKCNLLNEEI--KLKVQAEAPMQRRENNQETSAE 3074 Query: 831 MDHDRVVEKQLLEIEHENKELQKKNQILLEE-----NQNLQISLSDMQQHYNALVEKANR 885 DH +++ Q + EN+ L+++N L EE + ++ + ++ N + A++ Sbjct: 3075 KDHYQILISQNQRLIQENQRLKEENDKLKEEYSYYADNSVTLQQTNPVSGQNTASQSASK 3134 Query: 886 T--DLAESESTKYQTQLRDLESNLKR----ITHEHQTLI--VQKKKEIE----DLEIEFN 933 DL ++++T + Q++ L+ + + I Q ++ +Q+K++ E +L IEFN Sbjct: 3135 PAQDL-QTQNTDIELQVQILQEQISKQNEQIVKNEQNILEFIQQKEQQEQQYHNLLIEFN 3193 Query: 934 T------QIESAIRDKKVLNEKYEKNIEYVT--------QLEAQLQEYKNNIENLNMNVE 979 + E+ IR + +K EY + Q Q N ++N N+ + Sbjct: 3194 NVKNKLIEKENEIRFLQQYADKLSSQQEYTVYSTEGNNNNRQQQQQHIPNQLQNQNVKIR 3253 Query: 980 ELNKMNLE-------LIDKHVQKQQTQ--SPDYTEQYINEINKLNALLKQKDEEIIALNQ 1030 ++ + E + ++ ++ S + + + +N +NA A Sbjct: 3254 NISFLEQEGSQFEENQFEDYIHQEDAHRGSVHTSAEIVVNVNDINASNTLGRGFAQASGS 3313 Query: 1031 KINNAQVSYMSMVSDYESKLAQ-FTTKLENMEEEMQRV-SKQLLDSKQHNEELQILVREQ 1088 + NN Q S + + +S + Q N ++E V + Q +S EE ++++ Sbjct: 3314 QQNNQQNSNIRNSNSMQSNILQGLNFNANNQQDEETNVQNNQPYNSNLSVEEGFAVLQKI 3373 Query: 1089 DDQIKELK-ETKLTFEMN-IPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXL-KVQ 1145 D ++++ + E+N I K + +S + + + + K+Q Sbjct: 3374 DQAMEKIVWDMDCNEELNDIEKNQSFCSNSISQNLRLLMEKIHKSTSNRTLDNERIEKLQ 3433 Query: 1146 EE-EEFIQERSVLQEQSAKLNTELQECYTKIIQ-LETLNTELTGHDV----VNQEQINQL 1199 + EE ++ + L ++ +L + I+Q + + +++ D+ ++QI Q Sbjct: 3434 AKLEEKDEQIAFLNQKLQELQNVQKLLKRSIVQDINEKDPDVSRIDINPHSPKEQQIQQP 3493 Query: 1200 KSKLEQLNTENDNLLST---VAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHE 1256 S NL V EL+ + +R + EL + L DF+ + Sbjct: 3494 SSPSASPKKSAKNLQQLKDEVRELKYQVQDLTYER--DQLELENERLQMEIRDFENEQER 3551 Query: 1257 LRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQN-----KLQDKEEHLRNLQE 1311 ++ Q+S + + +QL QS +E ++I+ T L +L+ K E Sbjct: 3552 VQSQISLLKQEIKQL----QSQNIDEGSRIIKQTLKTILPKFLNIIQLKSKTESQNQEAT 3607 Query: 1312 KYADV-INQIEILRSE 1326 +Y +V +N +E E Sbjct: 3608 QYLNVMLNLLEFSEPE 3623 Score = 77.4 bits (182), Expect = 3e-12 Identities = 157/807 (19%), Positives = 332/807 (41%), Gaps = 77/807 (9%) Query: 768 ESELSKYK-SRICRLEESIAVMEDRRYSLERKA-----DQLGSYLQEKQKAYSEYTIQED 821 E E KYK ++I + +E+I + + + S + + +Q+ +QE + E I D Sbjct: 312 EKEYYKYKYNKILKDKEAITMQTEYQMSQKEEEVNYLKEQIQKLMQESRNVLHENKILSD 371 Query: 822 E---LVNRLAVLMDHDRVVEKQLLEIEHENKEL-----QKKNQILL-----EENQNLQIS 868 E L ++ L VEK+ + + K++ QK +QI + N N + Sbjct: 372 ENEVLQTKIKTLKAKLAEVEKKSADRKASLKQVYSILQQKDDQIKMLQANNNNNNNNMNN 431 Query: 869 LSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDL 928 ++ Q +A + A+ + + + QL ++E + H+ + + QK I +L Sbjct: 432 FNNAIQQNSASLAAASNSIIINQIKDDFARQLAEVEKSFLNQFHQIERAVNQKNDIIANL 491 Query: 929 EIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEEL---NKMN 985 E QI++ K+ + + ++ + K N +N E+L KM+ Sbjct: 492 E----DQIKNLNLSKRNITSNNKIDLSSPIEFTLSNNTSKRNQNANTVNQEQLIRAKKMD 547 Query: 986 LELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSD 1045 LE +++ +P+ Q EI ++ + + + E+I + Q ++ + +D Sbjct: 548 LEAKRENLVDIIQNNPNLPTQKRQEIQQIISHINNQMIELI-------DYQATHPDVEND 600 Query: 1046 YESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQ--IKELKETKLTFE 1103 E + LE ++++ + Q+ + N L+ + +Q +KE + K E Sbjct: 601 QEHGSVGSSNSLEGNKQDIAELRMQIEEYCNKNIMLERENEQLQEQFLLKEKETEKFIGE 660 Query: 1104 MNIPKTEGMI---ISSTIEPMSDDANN-VDXXXXXXXXXXXXLKVQEEEEFIQERSV-LQ 1158 + I + I + S +E ++ + N V +K + E + L Sbjct: 661 LQILLNQLRIQDQVQSDVETLNQNERNLVSLSISNLGESLGAIKEVVNSYKMHENQIQLL 720 Query: 1159 EQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQ--EQINQLKSKLEQLNTENDNLLST 1216 EQ ++ + QE T +Q ++ +++ Q Q+ LKS L+Q + N +L Sbjct: 721 EQQLQIAIQSQENLTNQLQNNLISENSQKSEIIKQLDSQLQNLKSLLQQEQSINSDLQEE 780 Query: 1217 VAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQ 1276 R I DQ ++++Q + + K + Q S SKY+Q Sbjct: 781 NGRQRERIEQLRDQ-----LDIFRQ--KDKSSQQSKYNDDNSSQYSQLFSKYQQ------ 827 Query: 1277 SSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFX- 1335 Q + N++V + ++ K+Q+ + + + ++ KY ++ + ++ I D++ A Sbjct: 828 --QQVQFNEVVRERDI--IEQKIQEMQRNYKEVKSKYEKSKDERKKMQKMISDQQQAITQ 883 Query: 1336 ----XXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXX 1391 DL+ + + +Q Q+Q+ + N + + + Sbjct: 884 LKKYSQSDEQVENLNQIINDLKNKLINQQQQQQQNNKDQYSSNTE-ELNQDLTVIKKRMS 942 Query: 1392 XXRVNDAEAKVLELTHQLELKD-SEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIED 1450 + N A+ + E KD S+ +++ + L + ND E +RQ E +I + Sbjct: 943 ELQQNQADLEQKNKKLYTEKKDLSKAFKEVSKLNSELQRSND--EKIRQN-SELANQISE 999 Query: 1451 LTYEKESELAILRLKMHENANHYETMQKESEI----ERVKLIEELNVKITESVSLNKQVA 1506 L+ ++ EL+ ++ + + KE+ I + K E ++ I E+ KQ+ Sbjct: 1000 LS-KQNQELSKANAELAKQNSEVTRAFKEARILGSSDSHKNSEGKHLAI-EAAEQQKQIR 1057 Query: 1507 ELNKALEEEVAKTNEMQTALENQEIEI 1533 +L K +E+ K N+ Q ++ QE+++ Sbjct: 1058 DLQKQ-NQELLKQNQ-QLLMQMQEVQL 1082 Score = 56.8 bits (131), Expect = 5e-06 Identities = 140/775 (18%), Positives = 318/775 (41%), Gaps = 62/775 (8%) Query: 860 EENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIV 919 ++NQN Q ++ Q+ N + ++ N + + S + R+ N+ ++ Q ++ Sbjct: 165 QQNQNNQY-INRQSQYQNYMQQEQNISPQPRNHSNRSINNNRNNIDNIAQV----QNIVQ 219 Query: 920 QKKKEIEDLEI--EFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMN 977 +++++++ + +F S R+ + N+ ++ Q Y NN + + Sbjct: 220 KQQQQLQQFQPHQQFGVIRASPYRNNENQNQGTSQSPYNNNNNNNQQSPYYNNRQQHSPY 279 Query: 978 VEELNKM----NLELIDK---HVQKQQTQSPDYTEQYINEINKL----NAL-------LK 1019 ++L + E ID+ HV ++ + E Y + NK+ A+ + Sbjct: 280 DDQLEQTYPTNENEDIDRQIVHVIRESKANRSEKEYYKYKYNKILKDKEAITMQTEYQMS 339 Query: 1020 QKDEEIIALNQKIN-----NAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDS 1074 QK+EE+ L ++I + V + + + E+++ Q TK++ ++ ++ V K+ D Sbjct: 340 QKEEEVNYLKEQIQKLMQESRNVLHENKILSDENEVLQ--TKIKTLKAKLAEVEKKSADR 397 Query: 1075 KQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXX 1134 K +++ +++++DDQIK L+ N+ I ++ ++ +N++ Sbjct: 398 KASLKQVYSILQQKDDQIKMLQANNNNNNNNMNNFNNAIQQNSAS-LAAASNSIIINQIK 456 Query: 1135 XXXXXXXLKVQEE--EEFIQ-ERSVLQEQSAKLNTELQECYTKIIQLE-TLNTELTGHDV 1190 +V++ +F Q ER+V Q+ N E Q + + T N ++ Sbjct: 457 DDFARQLAEVEKSFLNQFHQIERAVNQKNDIIANLEDQIKNLNLSKRNITSNNKIDLSSP 516 Query: 1191 VNQEQINQLKSKLEQLNTENDNLL--STVAELRSSISSAVD--QRGFEIAELWKQHLAQR 1246 + N + + NT N L + +L + + VD Q + +Q + Q Sbjct: 517 IEFTLSNNTSKRNQNANTVNQEQLIRAKKMDLEAKRENLVDIIQNNPNLPTQKRQEIQQI 576 Query: 1247 EADFQKTEHEL-RVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEH 1305 + EL Q + + + +Q SV SS E NK + + L ++Q +E Sbjct: 577 ISHINNQMIELIDYQATHPDVENDQEHGSVGSSNSLEGNK----QDIAEL--RMQIEEYC 630 Query: 1306 LRNLQEKYADVINQIEILRSEIEDEK-VAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQE 1364 +N+ + + Q + L E E EK + D+ T NQ+ + + Sbjct: 631 NKNIMLERENEQLQEQFLLKEKETEKFIGELQILLNQLRIQDQVQSDVETLNQNERNLVS 690 Query: 1365 QSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYT 1424 SI N+ E +K+ ++++ + ++LE Q+ ++ E T++ Sbjct: 691 LSISNLGESLGAIKE---------VVNSYKMHENQIQLLEQQLQIAIQSQE--NLTNQLQ 739 Query: 1425 ITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIER 1484 L N + + +QL + ++ L +++S + L+ + E ++ + +I R Sbjct: 740 NNLISENSQKSEIIKQLDSQLQNLKSLLQQEQSINSDLQEENGRQRERIEQLRDQLDIFR 799 Query: 1485 VKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQ 1544 K K + S Q ++L +++ + NE+ + E +I + ++ Sbjct: 800 QKDKSSQQSKYNDDNS--SQYSQLFSKYQQQQVQFNEVVRERDIIEQKIQEMQRNYKEVK 857 Query: 1545 NMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDLAMYMLHQR 1599 + S + +K SD +Q + + + E ++ + + DL +++Q+ Sbjct: 858 SKYEKSKDERKKMQKMISDQQQAITQLKKYSQSDEQVENLNQIINDLKNKLINQQ 912 >UniRef50_A2DA80 Cluster: Viral A-type inclusion protein, putative; n=1; Trichomonas vaginalis G3|Rep: Viral A-type inclusion protein, putative - Trichomonas vaginalis G3 Length = 2250 Score = 180 bits (437), Expect = 4e-43 Identities = 269/1309 (20%), Positives = 569/1309 (43%), Gaps = 123/1309 (9%) Query: 329 ELLEHLNCQIRQTNKELENKLATM-GTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWS 387 EL+++ + + N +L +L+++ + S +S+ K+ L+S KSG T +K+ + Sbjct: 195 ELMQN-KLNLEKENNKLSTQLSSLQSSSSDNISNLKKERDELVSIKSGILTVLGLKND-N 252 Query: 388 QLSSETLNQDTDKKINKNEIAKLEMVIQSLN---KDLVDKEYVISEKDTXXXXXXXXXXG 444 Q+ N KI + I+ L + + K L+ + E+ Sbjct: 253 QIEPTINNLLNSHKILQQAISSLGCSPEKTHETIKQLIQHHQNLKEQQDAITKMLKSNPS 312 Query: 445 KDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEK 504 + Q L+ + E + + N++ Q +L + N IK++ ++ K Sbjct: 313 EIPSQIQNLLDAKNSSEKQAKNLKSELGKTTNKLLDAQNELNDKANS-IKNLEYENDQTK 371 Query: 505 --LKSAEEQITQLNDEIDAANKNMIKVKS----NHKLKLKQMQKTIDNFSKVSDSNKEIV 558 +K EQ+ N ++ ++ KS N LK +Q DN + SN+ + Sbjct: 372 QTVKRLNEQLADANRKLHETEVSLETTKSQLQQNENLK-SLIQSEYDNSRQ--HSNELVE 428 Query: 559 RLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRM-----IES--DVYKKMIE-MENLAE 610 +LT+EL S++ +L+ + + + ++ + IE+ ++ MIE + N Sbjct: 429 KLTQELTSKSEEATKLKSQVSEMLSRIQQAENTKQALQSSIETTRNMTNNMIEGLHNELN 488 Query: 611 TRLKAISLLESQKFDLVQELHI--------------LQQKYDEVEDKLADISQLQSDQVC 656 ++ I+ L++Q L +E I LQ D +D+L D S ++ Sbjct: 489 SKNDEIAKLQAQNATLHREFEISQAKLQQTETQRKSLQDDLDSTQDQLNDTESKLSTEIS 548 Query: 657 SEIKSV-HLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQ 715 ++ K + +L+ Q+D+++ +E+ + +E+ +Q K + + ++ NKLQN I Sbjct: 549 TKDKEIANLKNQLDSVNKKNEEMEIQLESFNAKAKQYQNDFKSSQQKQTELENKLQNEIA 608 Query: 716 ENMDLTDKLEKM---SAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELS 772 + + KL+ S K ++ ++H Q +A + I+++ +E S Sbjct: 609 QKTETIAKLQSKITESKRKQTDTANLLDHTSNQLKILQSEYEATKKNHSQAIKDLSAESS 668 Query: 773 KYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMD 832 + I RL ++ + + +LE +Q + +A S+++ EL+ L + Sbjct: 669 EKTKEIGRLMNEVSAAKRAQLALENSKQT----IQAEYEASSKHS---SELIENLK-NEN 720 Query: 833 HDRVVEKQLLEIEHEN-KELQKKNQILLEENQN-LQISLSDMQQHYNALVEKANRT-DLA 889 +V E ++ E+EN K N + L++N+ LQI SD++ + +K N T Sbjct: 721 SQKVAELAKMKAENENLKRSNDVNNLKLKDNETALQILKSDLE----TIKQKNNETIGKL 776 Query: 890 ESESTKYQTQLRDLESNLKRITHEHQTL---IVQKKKEIEDLEIEFNTQIESAIRDKKVL 946 SE ++ + DL+SNL +T ++ L + K +I E+ +K+ Sbjct: 777 TSEISEKSKENLDLKSNLADMTRQNTELNSQVETLKSQISQNEVLKKLMENEYANNKEET 836 Query: 947 NEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQ 1006 + K ++ T+ ++ + K I NL+ +++N N++ ++ V + + + Sbjct: 837 QQFLAKAVQENTEKTKEINDLKAEISNLSSKNQQMNS-NIDSLNSQVSNLTSSNEELKNN 895 Query: 1007 YINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQR 1066 Y + ++ K +EI L +K N++++ S +S ++++A+ T LE + E + Sbjct: 896 YQKLVESSEQTIQGKIKEISDLKEK--NSKLN--SNISLKDAEIAENTKNLEALHENAAK 951 Query: 1067 VSKQLLDSKQHNEELQILVREQDDQIKELKETK--LTFEMNIPKTEGMIISSTIEPMSDD 1124 K LL KQ E+++ E + + L ETK L ++ + K I I+ ++D Sbjct: 952 --KDLL-VKQLQEQIRNDKNEIANLTQTLDETKSSLNHDIIVLKNSNDIKDQQIQSLNDH 1008 Query: 1125 ANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTE 1184 N+++ K + E+ Q L++++ KLN +LQ +I +L E Sbjct: 1009 INSLNDTSMNAVNEQINAKQKLSEQITQ----LEDENNKLNNQLQSDKIEISKLNVALGE 1064 Query: 1185 LTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSS----ISSAVDQRGFEIAELWK 1240 Q I++ +++ N + +L + ++ S I++ Q EI+++ Sbjct: 1065 KDSLAAAKQNVIDEQNVTIQKQNKKIADLQGDIGKMNISHEDEIANIKLQHVKEISDIKA 1124 Query: 1241 QHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQ 1300 QH+ + Q+T+ + +S + KY Q + Q++ NK+ ++S Q + Sbjct: 1125 QHIKELADKEQETKKLIESIISDNQQKYSQ----SSNELQDKLNKL-----MSSSQEIIS 1175 Query: 1301 DKEEHLRNLQEKYADVINQIE-ILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSY 1359 +K++ + ++EK+ + ++ ++ LRSE E+ + +LR + Sbjct: 1176 EKQKEISEMKEKHQNEMSLLQNNLRSEKENLRAEKDKEISDLKDKYDLELSNLRLKLNQL 1235 Query: 1360 KQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQL-ELKDSEIYQ 1418 +++ I ++NE++ ++D E + + +Q+ + K EI + Sbjct: 1236 NSSKDKEISDLNEKH-----------------HNEISDLEKNLRDEMNQMQQAKKDEINE 1278 Query: 1419 KTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQK 1478 + L+Q E+ ++Q K I DL + +E+ L+ N ++ Sbjct: 1279 LREKQRQELSQSRTEYSQLQQNSA---KEISDLNEKHHNEMKDLQ-------NSFKQEMD 1328 Query: 1479 ESEIERVKLIEELNVKITE-SVSLNKQVAELNKALEEEVA-KTNEMQTALENQEIEIVTL 1536 + + + K I+ELN K+ + +S + +++EL + + E + K+ E+ + EI +L Sbjct: 1329 KLQDAKTKEIQELNDKLNQLQLSKSNEISELKEKQQNEFSLKSKEISGIKQKHHQEIDSL 1388 Query: 1537 N----DEITNLQ-NMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKEL 1580 N +EI N+Q N V + +H D + +D N++L Sbjct: 1389 NEKHLEEIENMQVNHVNELQTLKDQHHQQILDLQNQSRIDMDLVKNQKL 1437 Score = 139 bits (337), Expect = 5e-31 Identities = 282/1456 (19%), Positives = 601/1456 (41%), Gaps = 145/1456 (9%) Query: 215 KQQMTKMQENFI-AMEAEWKDEKQRLLKDIESKDVRISSLEEANKL---LEAARFEISLE 270 KQ K EN + + D+ LL+++ + + +E NKL L + + S Sbjct: 167 KQLYQKQLENITKTINCKDADKIPTLLQELMQNKLNLE--KENNKLSTQLSSLQSSSSDN 224 Query: 271 HSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKI-E 329 S L +E ++ IEP+ + I+++ +K E Sbjct: 225 ISNLKKERDELVSIKSGILTVLGLKNDNQIEPTINNLLNSHKILQQAISSLGCSPEKTHE 284 Query: 330 LLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQL 389 ++ L Q Q KE ++ + M +S PS+ + L ++ S A +KS + Sbjct: 285 TIKQL-IQHHQNLKEQQDAITKM-LKSNPSEIPSQIQNLLDAKNSSEKQAKNLKSELGKT 342 Query: 390 SSETLNQDTDKKINKNEIAKLE-------MVIQSLNKDLVDKEYVISEKDTXXXXXXXXX 442 +++ L+ + N I LE ++ LN+ L D + E + Sbjct: 343 TNKLLDAQNELNDKANSIKNLEYENDQTKQTVKRLNEQLADANRKLHETEVSLETTKSQL 402 Query: 443 XGKDTLIAQLQLEHQQHMEGPS-LIHVGTN--TEDVNEIAKVQEQLKQELNDEIKDVNVK 499 + L + +Q E+ + + L+ T T E K++ Q+ + L+ + N K Sbjct: 403 QQNENLKSLIQSEYDNSRQHSNELVEKLTQELTSKSEEATKLKSQVSEMLSRIQQAENTK 462 Query: 500 DLIEKLKSAEEQITQ-----LNDEIDAANKNMIKVKSNH----------KLKLKQMQKTI 544 ++ +T L++E+++ N + K+++ + + KL+Q + Sbjct: 463 QALQSSIETTRNMTNNMIEGLHNELNSKNDEIAKLQAQNATLHREFEISQAKLQQTETQR 522 Query: 545 DNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNL--QLHLVDYDSGRM---IESDVY 599 + DS ++ + TE LS +++ ++E NL QL V+ + M +ES Sbjct: 523 KSLQDDLDSTQDQLNDTES--KLSTEISTKDKEIANLKNQLDSVNKKNEEMEIQLESFNA 580 Query: 600 KKMIEMENLAETRLKAISLLESQKFDLVQELHI---LQQKYDEVEDKLADISQLQSDQVC 656 K + ++ K L + ++ Q+ LQ K E + K D + L D Sbjct: 581 KAKQYQNDFKSSQQKQTELENKLQNEIAQKTETIAKLQSKITESKRKQTDTANLL-DHTS 639 Query: 657 SEIKSVHLE---------EQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIM 707 +++K + E + I LSA E I L + LEN K+ I Sbjct: 640 NQLKILQSEYEATKKNHSQAIKDLSAESSEKTKEIGRLMNEVSAAKRAQLALENSKQTIQ 699 Query: 708 NKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENI 767 + + + + +L + L+ +++K++EL AK+ E ++ ++ + K+++ + ++ + Sbjct: 700 AEYEASSKHSSELIENLKNENSQKVAEL-AKMKAENENLKRSNDVNNLKLKDNETALQIL 758 Query: 768 ESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRL 827 +S+L K + E+I + ++ L S L + + +E Q + L +++ Sbjct: 759 KSDLETIKQKN---NETIGKLTSEISEKSKENLDLKSNLADMTRQNTELNSQVETLKSQI 815 Query: 828 AVLMDHDRVVEKQLLEIEHEN--KELQKKNQILLEENQNLQISLSDMQQHYNALVEKANR 885 + V K+L+E E+ N +E Q+ ++EN ++D++ + L K + Sbjct: 816 S-----QNEVLKKLMENEYANNKEETQQFLAKAVQENTEKTKEINDLKAEISNLSSKNQQ 870 Query: 886 T----DLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIES--A 939 D S+ + + +L++N +++ + I K KEI DL+ E N+++ S + Sbjct: 871 MNSNIDSLNSQVSNLTSSNEELKNNYQKLVESSEQTIQGKIKEISDLK-EKNSKLNSNIS 929 Query: 940 IRDKKV---------LNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEEL-NKMNLELI 989 ++D ++ L+E K V QL+ Q++ KN I NL ++E + +N ++I Sbjct: 930 LKDAEIAENTKNLEALHENAAKKDLLVKQLQEQIRNDKNEIANLTQTLDETKSSLNHDII 989 Query: 990 DKHVQKQQTQSPDYTEQYINE-INKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYES 1048 V K D Q +N+ IN LN D + A+N++IN A+ ++ E Sbjct: 990 ---VLKNSNDIKDQQIQSLNDHINSLN------DTSMNAVNEQIN-AKQKLSEQITQLED 1039 Query: 1049 KLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPK 1108 + + +L++ + E+ +++ L + Q ++ EQ+ I++ + + +I K Sbjct: 1040 ENNKLNNQLQSDKIEISKLNVALGEKDSLAAAKQNVIDEQNVTIQKQNKKIADLQGDIGK 1099 Query: 1109 TEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTEL 1168 M IS E + +V L +E+E S++ + K + Sbjct: 1100 ---MNISHEDEIANIKLQHVKEISDIKAQHIKELADKEQETKKLIESIISDNQQKYSQSS 1156 Query: 1169 QECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLE-QLNTENDNLLSTVAELRSS---- 1223 E K+ +L + + E+ Q++I+++K K + +++ +NL S LR+ Sbjct: 1157 NELQDKLNKLMSSSQEIISE---KQKEISEMKEKHQNEMSLLQNNLRSEKENLRAEKDKE 1213 Query: 1224 ISSAVDQRGFEIAEL---WKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQ 1280 IS D+ E++ L Q + ++ + + ++S E ++ +Q + + Sbjct: 1214 ISDLKDKYDLELSNLRLKLNQLNSSKDKEISDLNEKHHNEISDLEKNLRDEMNQMQQAKK 1273 Query: 1281 EETNKIVTMEQVTSLQNKL------QDKEEHLRNLQEKY----ADVINQIEILRSEIEDE 1330 +E N++ ++ Q++ Q+ + + +L EK+ D+ N + +++D Sbjct: 1274 DEINELREKQRQELSQSRTEYSQLQQNSAKEISDLNEKHHNEMKDLQNSFKQEMDKLQDA 1333 Query: 1331 KVA----FXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKS--SXXX 1384 K +L+ + Q+ ++ + I I +++ Q S Sbjct: 1334 KTKEIQELNDKLNQLQLSKSNEISELKEKQQNEFSLKSKEISGIKQKHHQEIDSLNEKHL 1393 Query: 1385 XXXXXXXXXRVNDAEA-------KVLELTHQLELK-DSEIYQKTHEYTITLTQRNDEFEN 1436 VN+ + ++L+L +Q + D QK E T + +DE E Sbjct: 1394 EEIENMQVNHVNELQTLKDQHHQQILDLQNQSRIDMDLVKNQKLKEITELNKKHHDELEK 1453 Query: 1437 VRQQLVEYEKRIEDLTYEKESELAILRLKMHE--------NANHYETMQKESEIERVKLI 1488 ++ +++ ++ + +K E+ + K HE + N + +QK + E L+ Sbjct: 1454 LQ---IDHRIELDQMNSQKLKEITAMNDKHHEEIIAIQNSSRNELDKIQKTRQQEVSGLM 1510 Query: 1489 EELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVR 1548 + + E+ + + + N +L+ E +++ LEN ++I + E+T +Q+ Sbjct: 1511 AQRAKDLQENTKTIENLKKENSSLQVE---NKTLKSQLENIRLQIKETSKELTEMQSAFS 1567 Query: 1549 ASSSKIQKHVSFASDT 1564 S + +S T Sbjct: 1568 NRSRVFDESLSLMRST 1583 Score = 131 bits (316), Expect = 2e-28 Identities = 259/1214 (21%), Positives = 526/1214 (43%), Gaps = 130/1214 (10%) Query: 447 TLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKV-QEQLKQELNDEIKDVNVKDLIEKL 505 ++++ L E Q + + I N +D ++I + QE ++ +LN E ++ + + L Sbjct: 158 SVVSNLLQEKQLYQKQLENITKTINCKDADKIPTLLQELMQNKLNLEKENNKLSTQLSSL 217 Query: 506 KSAE-EQITQLNDEIDAANKNMIKVKSN--HKLKLKQMQKTIDNFSKVSDSNKEIVRLTE 562 +S+ + I+ L E D ++ +KS L LK + + + +S+K + + Sbjct: 218 QSSSSDNISNLKKERD----ELVSIKSGILTVLGLKNDNQIEPTINNLLNSHKILQQAIS 273 Query: 563 ELHHLSQKVAELEEEKGNLQLHLVDYDSG--RMIESDVYKKMIEMENLAETRLKAISLLE 620 L +K E ++ +L + +M++S+ + +++NL + + + + Sbjct: 274 SLGCSPEKTHETIKQLIQHHQNLKEQQDAITKMLKSNPSEIPSQIQNLLDAKNSSEKQAK 333 Query: 621 SQKFDLVQELHILQQKYDEVEDKLADISQL--QSDQVCSEIKSVHLEEQIDALSASKKEL 678 + K +L + + L +E+ DK I L ++DQ +K L EQ+ + E Sbjct: 334 NLKSELGKTTNKLLDAQNELNDKANSIKNLEYENDQTKQTVK--RLNEQLADANRKLHET 391 Query: 679 ALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENM--DLTDKLEKMSAEK--ISE 734 + +E K +Q +K L + D + N + E + +LT K E+ + K +SE Sbjct: 392 EVSLETTKSQLQQ-NENLKSLIQSEYDNSRQHSNELVEKLTQELTSKSEEATKLKSQVSE 450 Query: 735 LLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVM------ 788 +L++I E +K Q I+ + IE + +EL+ I +L+ A + Sbjct: 451 MLSRIQQAENTKQALQSSIETTRNMTNNMIEGLHNELNSKNDEIAKLQAQNATLHREFEI 510 Query: 789 --------EDRRYSLERKADQLGSYLQE-KQKAYSEYTIQEDELVNRLAVLMDHDRVVEK 839 E +R SL+ D L + + K +E + ++ E+ N L ++ E+ Sbjct: 511 SQAKLQQTETQRKSLQDDLDSTQDQLNDTESKLSTEISTKDKEIANLKNQLDSVNKKNEE 570 Query: 840 QLLEIEHENKELQKKNQILLEENQNLQISLSD-MQQHYNALVEKANRTDLAESESTKYQT 898 +++E N + K+ Q + +Q Q L + +Q E + +ES + QT Sbjct: 571 MEIQLESFNAK-AKQYQNDFKSSQQKQTELENKLQNEIAQKTETIAKLQSKITESKRKQT 629 Query: 899 ---QLRDLESN-LKRITHEHQTLIVQKKKEIEDLEIEFN----------TQIESAIR--- 941 L D SN LK + E++ + I+DL E + ++ +A R Sbjct: 630 DTANLLDHTSNQLKILQSEYEATKKNHSQAIKDLSAESSEKTKEIGRLMNEVSAAKRAQL 689 Query: 942 ----DKKVLNEKYEKNIEYVTQLEAQLQ-EYKNNIENL------NMNVEELNKM-NLELI 989 K+ + +YE + ++ ++L L+ E + L N N++ N + NL+L Sbjct: 690 ALENSKQTIQAEYEASSKHSSELIENLKNENSQKVAELAKMKAENENLKRSNDVNNLKLK 749 Query: 990 DKHVQKQQTQSP-DYTEQYINE-INKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYE 1047 D Q +S + +Q NE I KL + + +K +E L+ K N A ++ + ++ Sbjct: 750 DNETALQILKSDLETIKQKNNETIGKLTSEISEKSKE--NLDLKSNLADMTRQN--TELN 805 Query: 1048 SKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEE-LQILVREQDDQIKELKETKLTFEMNI 1106 S++ +++ E + + + ++K+ ++ L V+E ++ KE+ + K E++ Sbjct: 806 SQVETLKSQISQNEVLKKLMENEYANNKEETQQFLAKAVQENTEKTKEINDLKA--EISN 863 Query: 1107 PKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEF---IQERSVLQEQSAK 1163 ++ ++S I+ ++ +N+ L E+ I+E S L+E+++K Sbjct: 864 LSSKNQQMNSNIDSLNSQVSNLTSSNEELKNNYQKLVESSEQTIQGKIKEISDLKEKNSK 923 Query: 1164 LNTELQECYTKIIQLETLNTELTGHDVVNQE-QINQLKSKLEQLNTENDNLLSTVAELRS 1222 LN+ + +I + T N E + ++ + QL+ ++ E NL T+ E +S Sbjct: 924 LNSNISLKDAEIAE-NTKNLEALHENAAKKDLLVKQLQEQIRNDKNEIANLTQTLDETKS 982 Query: 1223 SISSAV-------DQRGFEIAELWKQHL------AQREADFQ-KTEHELRVQLSAFESKY 1268 S++ + D + +I L H+ + + Q + +L Q++ E + Sbjct: 983 SLNHDIIVLKNSNDIKDQQIQSL-NDHINSLNDTSMNAVNEQINAKQKLSEQITQLEDEN 1041 Query: 1269 EQLLDSVQSSTQEETNKIVTMEQVTSL----QNKLQDKEEHLRNLQEKYADVINQIEILR 1324 +L + +QS E + V + + SL QN + ++ ++ +K AD+ I + Sbjct: 1042 NKLNNQLQSDKIEISKLNVALGEKDSLAAAKQNVIDEQNVTIQKQNKKIADLQGDIGKMN 1101 Query: 1325 SEIEDEKVAF-XXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXX 1383 EDE +L + Q K++ E SI++ N++ + +SS Sbjct: 1102 ISHEDEIANIKLQHVKEISDIKAQHIKELADKEQETKKLIE-SIISDNQQ--KYSQSS-- 1156 Query: 1384 XXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRN--DEFENVRQQL 1441 ++N + E+ + + + SE+ +K H+ ++L Q N E EN+R Sbjct: 1157 -----NELQDKLNKLMSSSQEIISEKQKEISEMKEK-HQNEMSLLQNNLRSEKENLR--- 1207 Query: 1442 VEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVS- 1500 E +K I DL + + EL+ LRLK+++ K+ E I +LN K +S Sbjct: 1208 AEKDKEISDLKDKYDLELSNLRLKLNQ-----LNSSKDKE------ISDLNEKHHNEISD 1256 Query: 1501 LNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNL-QNMVRASSSKIQKHVS 1559 L K + + +++ AK +E+ E Q E+ E + L QN + S +KH + Sbjct: 1257 LEKNLRDEMNQMQQ--AKKDEINELREKQRQELSQSRTEYSQLQQNSAKEISDLNEKHHN 1314 Query: 1560 FASDTKQGRDEQLD 1573 D + +++D Sbjct: 1315 EMKDLQNSFKQEMD 1328 Score = 120 bits (288), Expect = 4e-25 Identities = 249/1204 (20%), Positives = 498/1204 (41%), Gaps = 95/1204 (7%) Query: 160 VLQVKMKIMETTILDLQEKINE-KDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQM 218 + Q K++ ET LQ+ ++ +DQ+ + ++K +T K Sbjct: 510 ISQAKLQQTETQRKSLQDDLDSTQDQLNDTESKLSTEISTKDKEIANLKNQLDSVNK--- 566 Query: 219 TKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFE-ISLEHSKLAQE 277 K +E I +E+ + + ++ D +S + + LE + A + E I+ SK+ + Sbjct: 567 -KNEEMEIQLES-FNAKAKQYQNDFKSSQQKQTELENKLQNEIAQKTETIAKLQSKITES 624 Query: 278 LEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQ 337 + L E +K + L A +E TK+I L + Sbjct: 625 KRKQTDTANLLDHTSNQLKILQSEYEATKKNHSQAIKDLS-AESSEKTKEIGRLMNEVSA 683 Query: 338 IRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQD 397 ++ LEN T+ E +A SK S LI N+ + + +E L + Sbjct: 684 AKRAQLALENSKQTIQAEYEA---SSKHSSELIENLKNENSQKVAELAKMKAENENLKRS 740 Query: 398 TD---KKINKNEIA------KLEMVIQSLNKDLVDKEYVISEK---DTXXXXXXXXXXGK 445 D K+ NE A LE + Q N+ + ISEK + + Sbjct: 741 NDVNNLKLKDNETALQILKSDLETIKQKNNETIGKLTSEISEKSKENLDLKSNLADMTRQ 800 Query: 446 DT-LIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLK---QELNDEIKDVNVKDL 501 +T L +Q++ Q + L + N E N + Q+ L QE ++ K++N DL Sbjct: 801 NTELNSQVETLKSQISQNEVLKKLMEN-EYANNKEETQQFLAKAVQENTEKTKEIN--DL 857 Query: 502 IEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSK-VSDSNKEIVRL 560 ++ + + Q+N ID+ N + + S+++ QK +++ + + KEI L Sbjct: 858 KAEISNLSSKNQQMNSNIDSLNSQVSNLTSSNEELKNNYQKLVESSEQTIQGKIKEISDL 917 Query: 561 TEE----LHHLSQKVAELEEEKGNLQ-LH--LVDYD-SGRMIESDVYKKMIEMENLAETR 612 E+ ++S K AE+ E NL+ LH D + ++ + E+ NL +T Sbjct: 918 KEKNSKLNSNISLKDAEIAENTKNLEALHENAAKKDLLVKQLQEQIRNDKNEIANLTQTL 977 Query: 613 LKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVH-LEEQIDAL 671 + S L L I Q+ + D + ++ + V +I + L EQI L Sbjct: 978 DETKSSLNHDIIVLKNSNDIKDQQIQSLNDHINSLNDTSMNAVNEQINAKQKLSEQITQL 1037 Query: 672 SASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEK 731 +L +++ K++ +L + +K+ + QN I E K K A+ Sbjct: 1038 EDENNKLNNQLQSDKIEISKLNVAL----GEKDSLAAAKQNVIDEQNVTIQKQNKKIADL 1093 Query: 732 ISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDR 791 + + K+N + +I + + D+ ++I+ EL+ + +L ESI + Sbjct: 1094 QGD-IGKMNISHEDEI-ANIKLQHVKEISDIKAQHIK-ELADKEQETKKLIESIISDNQQ 1150 Query: 792 RYS-----LERKADQLGS----YLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLL 842 +YS L+ K ++L S + EKQK SE +++ N +++L ++ R EK+ L Sbjct: 1151 KYSQSSNELQDKLNKLMSSSQEIISEKQKEISE---MKEKHQNEMSLLQNNLR-SEKENL 1206 Query: 843 EIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRD 902 E + + K++ LE + NL++ L+ + + + N + +E + + LRD Sbjct: 1207 RAEKDKEISDLKDKYDLELS-NLRLKLNQLNSSKDKEISDLN--EKHHNEISDLEKNLRD 1263 Query: 903 LESNLKRI-THEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLE 961 + +++ E L ++++E+ E++ +++ ++ LNEK+ ++ L+ Sbjct: 1264 EMNQMQQAKKDEINELREKQRQELSQSRTEYSQLQQNSAKEISDLNEKHHNEMK---DLQ 1320 Query: 962 AQLQEYKNNIENL-NMNVEELN-KMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLK 1019 ++ + +++ ++ELN K+N + K + + + E + + +++ + + Sbjct: 1321 NSFKQEMDKLQDAKTKEIQELNDKLNQLQLSKSNEISELKEKQQNE-FSLKSKEISGIKQ 1379 Query: 1020 QKDEEIIALNQK----INNAQVSYMSMVSDYESKLAQFTTKLENMEE-EMQRVSKQLLD- 1073 + +EI +LN+K I N QV++++ + + + Q L+N +M V Q L Sbjct: 1380 KHHQEIDSLNEKHLEEIENMQVNHVNELQTLKDQHHQQILDLQNQSRIDMDLVKNQKLKE 1439 Query: 1074 ----SKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVD 1129 +K+H++EL+ L + ++ ++ KL I I + N +D Sbjct: 1440 ITELNKKHHDELEKLQIDHRIELDQMNSQKL---KEITAMNDKHHEEIIAIQNSSRNELD 1496 Query: 1130 XXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQ-ECYTKIIQLETLNTELTGH 1188 L Q ++ +QE + E K N+ LQ E T QLE + ++ Sbjct: 1497 KIQKTRQQEVSGLMAQRAKD-LQENTKTIENLKKENSSLQVENKTLKSQLENIRLQIKET 1555 Query: 1189 DVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREA 1248 E + ++ + + ST+ ++R + D EIA + Sbjct: 1556 SKELTEMQSAFSNRSRVFDESLSLMRSTLEKIRMILGLPADVSVEEIA----SSVDNLMK 1611 Query: 1249 DFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTS---LQNKLQDKEEH 1305 +F K H+L V A + L ++ E + +++++T+ LQN EH Sbjct: 1612 NFAK--HQLEV-CKALDLPKRSPLKEIRGKINELSGTSHSLQEITTNLGLQNSPDAINEH 1668 Query: 1306 LRNL 1309 ++ L Sbjct: 1669 IKTL 1672 Score = 94.3 bits (224), Expect = 2e-17 Identities = 224/1197 (18%), Positives = 491/1197 (41%), Gaps = 94/1197 (7%) Query: 145 THLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXX 204 T L++ ++ + +S +V K+ME + +E+ + +N T Sbjct: 802 TELNSQVETLKSQISQNEVLKKLMENEYANNKEETQQFLAKAVQENTEKTKEINDLKAEI 861 Query: 205 XXXXXXXEDTKQQMTKMQE---NFIAMEAEWKDEKQRLLKD----IESKDVRISSLEEAN 257 + + + N + E K+ Q+L++ I+ K IS L+E N Sbjct: 862 SNLSSKNQQMNSNIDSLNSQVSNLTSSNEELKNNYQKLVESSEQTIQGKIKEISDLKEKN 921 Query: 258 KLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLE 317 L + ISL+ +++A+ + L KQ E +K EI Sbjct: 922 SKLNS---NISLKDAEIAENTKNLEALHENAAKKDL-LVKQLQEQIRNDKNEI------- 970 Query: 318 IANMTE-LTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGR 376 AN+T+ L + L H ++ +N + ++ ++ +++ S ++ + Sbjct: 971 -ANLTQTLDETKSSLNHDIIVLKNSNDIKDQQIQSLNDHINSLNDTSMNA---VNEQI-- 1024 Query: 377 NTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXX 436 N K+ +QL E + + +K EI+KL + + + K+ VI E++ Sbjct: 1025 NAKQKLSEQITQLEDENNKLNNQLQSDKIEISKLNVALGEKDSLAAAKQNVIDEQNVTIQ 1084 Query: 437 XXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDV 496 I ++ + H+ + L HV EI+ ++ Q +EL D K+ Sbjct: 1085 KQNKKIADLQGDIGKMNISHEDEIANIKLQHV-------KEISDIKAQHIKELAD--KEQ 1135 Query: 497 NVKDLIEKLKSAEEQ-ITQLNDEI-DAANKNMI---KVKSNHKLKLKQMQKTIDNFSKVS 551 K LIE + S +Q +Q ++E+ D NK M ++ S + ++ +M++ N + Sbjct: 1136 ETKKLIESIISDNQQKYSQSSNELQDKLNKLMSSSQEIISEKQKEISEMKEKHQNEMSLL 1195 Query: 552 DSN----KEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIE-SDVYKKMI-EM 605 +N KE +R E+ +S + + E NL+L L +S + E SD+ +K E+ Sbjct: 1196 QNNLRSEKENLR-AEKDKEISDLKDKYDLELSNLRLKLNQLNSSKDKEISDLNEKHHNEI 1254 Query: 606 ENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQV--CSEIKSVH 663 +L + ++ ++ K D + EL Q++ E+ + SQLQ + S++ H Sbjct: 1255 SDLEKNLRDEMNQMQQAKKDEINELREKQRQ--ELSQSRTEYSQLQQNSAKEISDLNEKH 1312 Query: 664 LEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDK 723 E D ++ K+E+ + + + ++L + L+ K + +++L+ Q L K Sbjct: 1313 HNEMKDLQNSFKQEMDKLQDAKTKEIQELNDKLNQLQLSKSNEISELKEKQQNEFSLKSK 1372 Query: 724 LEKMSAEKISELLAKINHEEQSKIQT-QFGIDAKIQE-RDLYIENI-----ESELSKYKS 776 +K + + +N + +I+ Q ++Q +D + + I +S + Sbjct: 1373 EISGIKQKHHQEIDSLNEKHLEEIENMQVNHVNELQTLKDQHHQQILDLQNQSRIDMDLV 1432 Query: 777 RICRLEESIAVMEDRRYSLER-KADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDR 835 + +L+E + + LE+ + D Q + E T D+ + + + R Sbjct: 1433 KNQKLKEITELNKKHHDELEKLQIDHRIELDQMNSQKLKEITAMNDKHHEEIIAIQNSSR 1492 Query: 836 -VVEKQLLEIEHENKELQKKNQILLEEN----QNLQISLSDMQQHYNALVEKANRTDLAE 890 ++K + E L + L+EN +NL+ S +Q L + L Sbjct: 1493 NELDKIQKTRQQEVSGLMAQRAKDLQENTKTIENLKKENSSLQVENKTLKSQLENIRLQI 1552 Query: 891 SESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIE-DLEIEFNTQIESAIRDKKVLNEK 949 E++K T+++ SN R+ E +L+ ++I L + + +E L + Sbjct: 1553 KETSKELTEMQSAFSNRSRVFDESLSLMRSTLEKIRMILGLPADVSVEEIASSVDNLMKN 1612 Query: 950 YEKN-IEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYI 1008 + K+ +E L+ ++ ++ + + EL+ + L + SPD ++ Sbjct: 1613 FAKHQLEVCKALDL---PKRSPLKEIRGKINELSGTSHSLQEITTNLGLQNSPDAINEH- 1668 Query: 1009 NEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVS 1068 I L+ + ++ + E+ + + Q+S +++ E +Q +++ + EE + Sbjct: 1669 --IKTLHGVCRKLESEV-----RKRDTQLSGIAISLGAEDP-SQIDNQIQTILEENDNLK 1720 Query: 1069 KQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNV 1128 ++ S+ +N+ L + +++ + +L + + + ++ + +DD Sbjct: 1721 TEIDVSQMNNKSLCSTLGVDEEENVDRHVDRLIRDKSQMERAQKKLAELVGVENDD---- 1776 Query: 1129 DXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGH 1188 + + QE+ I +++ + L+ + +E + E++N + G Sbjct: 1777 NSSAVVYQKVAQMQRTQEQLTKILGTENIEDAVSDLHKQSEELNS---IFESVNNDENGS 1833 Query: 1189 DVVNQEQINQLKSKLEQLNTENDNLLSTVAELRS--SISSAVD-QRGFEIAELWKQHLAQ 1245 V Q + K + QL T+N NL S +AE+ ++S+ D +R + L + Sbjct: 1834 IVY---QASSQKEIVGQLITKNGNLSSQMAEIGKLMNVSTFQDIKRAINFLLSENERLTK 1890 Query: 1246 READFQKTEHELRVQLSA----FESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNK 1298 EAD + ++ + + + +L +V+++ T +++Q T L +K Sbjct: 1891 TEADGIELRQQIADIIDTPGILDTTNNDMILAAVRNTKNSLTETKESLDQQTKLMSK 1947 Score = 68.1 bits (159), Expect = 2e-09 Identities = 151/778 (19%), Positives = 310/778 (39%), Gaps = 72/778 (9%) Query: 806 LQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNL 865 LQ + + + D+L+ M + E+Q IE QK LLE+N+NL Sbjct: 23 LQVRDEINDQLQTTFDDLIGDKIQAMRLKKQTEEQQKAIEKLKTINQKLKTELLEKNKNL 82 Query: 866 QISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEI 925 + L+ +E+ R + + + + ++ +I Q K Sbjct: 83 NLVLNLFDIPDQISLEELERMVKNMKLHSDFYDLIAKAFGDKSEDNKDYSPIIAQLLKIF 142 Query: 926 EDLEIEFNT---QIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELN 982 DL+ T +I S + + + Y+K +E +T+ ++ + I L + + N Sbjct: 143 GDLKNSLQTDDDKIASVVSNLLQEKQLYQKQLENITK-TINCKD-ADKIPTLLQELMQ-N 199 Query: 983 KMNLELIDKHVQKQQTQSPDYTEQYINEINK-LNALLKQKDEEIIALNQKINNAQVSYMS 1041 K+NLE + + Q + + I+ + K + L+ K + L K +N ++ Sbjct: 200 KLNLEKENNKLSTQLSSLQSSSSDNISNLKKERDELVSIKSGILTVLGLKNDNQIEPTIN 259 Query: 1042 MVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLT 1101 + + L Q + L E+ KQL+ QH++ L +EQ D I TK+ Sbjct: 260 NLLNSHKILQQAISSLGCSPEKTHETIKQLI---QHHQNL----KEQQDAI-----TKML 307 Query: 1102 FEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQS 1161 K+ I S I+ + D N+ + + + + ++ L +++ Sbjct: 308 ------KSNPSEIPSQIQNLLDAKNSSEKQAKNLKSELG----KTTNKLLDAQNELNDKA 357 Query: 1162 AKL-NTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAEL 1220 + N E + TK ++ LN +L + E L++ QL +N+NL S + Sbjct: 358 NSIKNLEYENDQTK-QTVKRLNEQLADANRKLHETEVSLETTKSQLQ-QNENLKSLI--- 412 Query: 1221 RSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQ 1280 +S ++ Q E+ E Q L + + K + ++ LS + + E ++QSS Sbjct: 413 QSEYDNS-RQHSNELVEKLTQELTSKSEEATKLKSQVSEMLSRIQ-QAENTKQALQSSI- 469 Query: 1281 EETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXX 1340 ET + +T + L N+L K + + LQ + A + + EI +++++ + Sbjct: 470 -ETTRNMTNNMIEGLHNELNSKNDEIAKLQAQNATLHREFEISQAKLQQTE--------- 519 Query: 1341 XXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEA 1400 T+ +S + + + +N+ ++L +++ Sbjct: 520 -------------TQRKSLQDDLDSTQDQLNDTESKLSTEISTKDKEIANLKNQLDSVNK 566 Query: 1401 KVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFEN-----VRQQLVEYEKRIEDLTYEK 1455 K E+ QLE +++ Q +++ + Q+ E EN + Q+ K +T K Sbjct: 567 KNEEMEIQLESFNAKAKQYQNDFK-SSQQKQTELENKLQNEIAQKTETIAKLQSKITESK 625 Query: 1456 ESELAILRLKMHENANHYETMQKESEIER---VKLIEELNVKITESV-SLNKQVAELNKA 1511 + L H +N + +Q E E + + I++L+ + +E + + + E++ A Sbjct: 626 RKQTDTANLLDH-TSNQLKILQSEYEATKKNHSQAIKDLSAESSEKTKEIGRLMNEVSAA 684 Query: 1512 LEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRD 1569 ++A N QT E ++ I NL+N +++ K + + K+ D Sbjct: 685 KRAQLALENSKQTIQAEYEASSKHSSELIENLKNENSQKVAELAKMKAENENLKRSND 742 >UniRef50_A2FQ08 Cluster: Viral A-type inclusion protein, putative; n=1; Trichomonas vaginalis G3|Rep: Viral A-type inclusion protein, putative - Trichomonas vaginalis G3 Length = 2271 Score = 179 bits (435), Expect = 7e-43 Identities = 306/1507 (20%), Positives = 638/1507 (42%), Gaps = 177/1507 (11%) Query: 143 DVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXX 202 ++ + N +K+ ++ L + K +E+ DL+ ++N + I +K+K + Sbjct: 236 ELDNAKNELKQLHSSYDNLNNEHKSLESEKEDLENELNNANSTINSKDKELSKLQRD--- 292 Query: 203 XXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEA 262 + Q + K ++ DE Q L + ++ + NKLL+A Sbjct: 293 ---------NERLQNVNKENDDLKKENKSLDDEIQTLKNSNNDLNNKLQREQNQNKLLQA 343 Query: 263 ARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCE----EKTEIEEKGSLEI 318 A ++ +++ L +L ++ I E ++T + G L Sbjct: 344 ANDTLTNDNNDLNDKLTSSNNDRIKAESKANTAERELINAIAEGEELKQTNKQLNGQLNE 403 Query: 319 AN---------MTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPL 369 N + +L KK LE+ N +I+ +EL A + ++ KK + L Sbjct: 404 MNNNYKELQGKLNDLEKKANQLENANQRIQDLEQELAESQAESNGKDAKINELQKKANQL 463 Query: 370 -------ISRKSGRNTASK----MKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLN 418 + +++ + K +K + QL + K ++ KLE + + N Sbjct: 464 EPTEKKLVDKQNENDKLQKELDELKDKYDQLEKALKAAENRVKELLSQNEKLENSLDNAN 523 Query: 419 KDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEI 478 + K +S+++ + + L+ ++ + + ++ + Sbjct: 524 NLSLQKGDELSKRNETLADLKKRNQELEARVRDLESQNDDEKDN----ELAAKDSEIQNL 579 Query: 479 AKVQEQLKQELND---EIK----DVNVKDL-IEKLKSAEEQITQLNDEIDAANKNMIKVK 530 EQ K++LND ++K D++ KD I+KLK E+I +LN+++ AN + K++ Sbjct: 580 KSQLEQTKKDLNDTQEDLKTANNDLSAKDKEIQKLKRDNEKIAKLNEDLKEANDEIKKLE 639 Query: 531 SNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDS 590 N K L+ D SK+ ++ +E R E L Q++ E +E+ + + Sbjct: 640 -NEKDDLQSQLS--DKDSKLQNAMREKDRANNENATLKQQINECDEKLKKETGEKIKLNG 696 Query: 591 GRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKL--ADIS 648 + D+ +++ A+ + +A + Q + LQ K ++++ K AD Sbjct: 697 QK---GDLERELATANASAQQQKEATEFAQQQVQEKDARNKELQNKINDLQKKANAADNL 753 Query: 649 QLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDK-EQLYGTIKDLENDKEDIM 707 Q Q DQ+ S + + ++K+ L+ K E ++KD + + + Sbjct: 754 QQQVDQLKSMLDDANKSINDKDSQINEKQKELIETRKKASALEPTKQSLKDTQAELTEKQ 813 Query: 708 NKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENI 767 N L N +N +L +L+++ ++I +L + E + ++ Q +D K++ D+ IE + Sbjct: 814 NDLNNANNKNRELERELKELK-KQIGDL-----NRENNDLKEQ--LDDKVKNDDI-IEKL 864 Query: 768 ESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRL 827 ++ + ++I L+ V D +LE K ++L QKA E E++L + Sbjct: 865 RKQIDELNAKIQELQSQKPV--DNSSALEEKINEL-------QKAKQELEETENKLKDTT 915 Query: 828 AVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTD 887 LM D+ ++K +EH + +L + ++ L EN+ Sbjct: 916 DELMAKDKELQKANRGLEHLD-QLTRDLEVALAENK------------------------ 950 Query: 888 LAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLN 947 +A++E+++ +TQL + ++ L++ ++ T + +++ + N ++ A +D LN Sbjct: 951 IADAENSELKTQLANKDNELQKAKQDN-TRLQSNNEQLTANSDDLNKKLTDATKDNIKLN 1009 Query: 948 EKYEKNIEYVTQL-EAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQ 1006 + K++E + Q EA+L + ++E L V + + EL K Q+ S E+ Sbjct: 1010 GQV-KDLERLLQSKEAELDQQNQSVEQLKSQVTDKDDKLKELQSKLNDLQKELSEK--ER 1066 Query: 1007 YINEINKLNALLKQKDEEIIALNQKIN--NAQVSYMSMVSDYESKLAQFTTKLENMEEEM 1064 N N L + L D+EI + N+K+N N M+ V KL KL+ ++E+ Sbjct: 1067 LENLANSLQSKL---DDEIKSNNEKLNQLNELEKQMNEVQKKADKLQPTQDKLKYAQDEL 1123 Query: 1065 QRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKT--EGMIISSTIEPMS 1122 K+L S +N +LQ +++ Q +L E K E + G +I + + +S Sbjct: 1124 TEKQKELDASNANNRDLQKQIKDLKKQNDDLDEQKQKLEEQLDNNVKAGDVIGNLRKQIS 1183 Query: 1123 DD-ANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETL 1181 + A N D L +E E L+ Q ++ +L+E K +L+ + Sbjct: 1184 ELLAKNKDLEAKNKDNNGDELAAKEAE-----LESLKNQLEQIKKDLEE---KEEELKQV 1235 Query: 1182 NTELTGHDVVNQE--QINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELW 1239 N L+ D Q+ + N+ SKL++ + +N + + + + S + + E+ + Sbjct: 1236 NDNLSAKDKELQKLSRENEKNSKLQKDLEDANNQNKKLDDENNDLQSQLSTKDIELQK-- 1293 Query: 1240 KQHLAQREAD-FQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNK 1298 AQ+EA Q +L Q +K ++ S E N + + + + Sbjct: 1294 ----AQKEAGRLQNLVQKLEEQNKDLYNKLDEETAEKLKSNGEVRNAQLELAKTKANAED 1349 Query: 1299 LQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQS 1358 L + EHL+ + IN++ +E + + EN+ Sbjct: 1350 LSKENEHLQEQNNEKDSFINELRAKANEAQKKA----------------------GENE- 1386 Query: 1359 YKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQ 1418 ++Q Q I ++N + +L + ++N+A+ K ++ L+ S+ + Sbjct: 1387 --KLQNQ-INDLNSQIDELNNAISAQNETINDLKKKLNEAQKKANQV-EPLQQSLSDAKE 1442 Query: 1419 KTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLK-MHENANHY---- 1473 + +E + + N++ N +Q E ++R++DL E++ RLK ++N N+ Sbjct: 1443 ENNEKQEKIDELNEKLRNAEKQFKEADQRVKDLLTEQQ------RLKDSYDNINNMSLQK 1496 Query: 1474 --ETMQKESEIERVK-LIEELNVKITES--VSLNKQVAELNKALEEEVAKTNEMQTALEN 1528 E +KE+E++ +K +++L K S + ++ EL K LE+ + + +++ L+N Sbjct: 1497 EDELTKKENEVDTLKKALKDLQNKTNGSNDKEIAEKEQELEKQLEDALRDLSNVKSELDN 1556 Query: 1529 QEIEIVTLNDEITNLQNMVRASSSK---IQKHVSFASDTKQGRDEQLDNTM-NKELLDAV 1584 + E+ L+ NL N ++ S+ ++ ++ A+ T +D++L + E L V Sbjct: 1557 AKNELKQLHSSYDNLNNEHKSLESEKEDLENELNNANSTINSKDKELSKLQRDNERLQNV 1616 Query: 1585 PRAELDL 1591 + DL Sbjct: 1617 NKENDDL 1623 Score = 175 bits (427), Expect = 6e-42 Identities = 296/1512 (19%), Positives = 676/1512 (44%), Gaps = 137/1512 (9%) Query: 140 QLGDVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINE-KDQIIEAKNKATTXXXX 198 ++ D+ SN + + ++ + L+ ++ ET+ DL K+N+ + ++ E + KA Sbjct: 51 KVNDLEKKSNQLDDANSRIKELEDELTESETSKDDLSNKLNDLQKKLNELQKKANQLDQA 110 Query: 199 XXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANK 258 D++Q+ T+ Q+ ++ + +D ++ + K ++ K+ LE+ANK Sbjct: 111 KKDLA---------DSQQENTEKQKEVDDLKTQLRDLEKEM-KQLQKKN---DDLEKANK 157 Query: 259 LLEAARFEISL----EHSKLAQELEQXXXXXXXXXXXXXXLAKQ----SIEPSCEEKTEI 310 L+ + E S+ E SK Q L L Q + + ++ EI Sbjct: 158 DLQE-KLEDSMKQESELSKKDQVLANLKKALADATNKVKDLENQLNGSNDKDIAAKEREI 216 Query: 311 EE-KGSLEIA--NMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGS 367 E K LE A +++ + +++ ++ Q+ + L N+ ++ +E + + + + Sbjct: 217 ESLKSQLEDALRDLSNVKSELDNAKNELKQLHSSYDNLNNEHKSLESEKEDLENELNNAN 276 Query: 368 PLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDK-EY 426 I+ K SK++ +L + D KK NK+ +++ +++ N DL +K + Sbjct: 277 STINSKD--KELSKLQRDNERLQNVNKENDDLKKENKSLDDEIQ-TLKNSNNDLNNKLQR 333 Query: 427 VISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQE--Q 484 ++ + L +L + ++ S + E +N IA+ +E Q Sbjct: 334 EQNQNKLLQAANDTLTNDNNDLNDKLTSSNNDRIKAESKANTAER-ELINAIAEGEELKQ 392 Query: 485 LKQELNDEIKDVN--VKDLIEKLKSAEEQITQL---NDEIDAANKNMIK--VKSNHK-LK 536 ++LN ++ ++N K+L KL E++ QL N I + + + +SN K K Sbjct: 393 TNKQLNGQLNEMNNNYKELQGKLNDLEKKANQLENANQRIQDLEQELAESQAESNGKDAK 452 Query: 537 LKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIES 596 + ++QK + ++ + K++V E L +++ EL+++ L+ L + E+ Sbjct: 453 INELQKKAN---QLEPTEKKLVDKQNENDKLQKELDELKDKYDQLEKAL------KAAEN 503 Query: 597 DVYKKMIEMENLAETRLKAISLLESQKFDLVQE----LHILQQKYDEVEDKLADISQLQS 652 V K+++ E L + L QK D + + L L+++ E+E ++ D+ Sbjct: 504 RV-KELLSQNEKLENSLDNANNLSLQKGDELSKRNETLADLKKRNQELEARVRDLESQND 562 Query: 653 DQVCSEI--KSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKL 710 D+ +E+ K ++ L +KK+L E+LK L K+++ K D K+ Sbjct: 563 DEKDNELAAKDSEIQNLKSQLEQTKKDLNDTQEDLKTANNDLSAKDKEIQKLKRD-NEKI 621 Query: 711 QNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESE 770 ++ + D+++K+ EK +L ++++ ++ SK+Q + + ++ + Sbjct: 622 AKLNEDLKEANDEIKKLENEK-DDLQSQLS-DKDSKLQNAMREKDRANNENA---TLKQQ 676 Query: 771 LSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKA--YSEYTIQEDELVNRLA 828 +++ ++ + + ++ LER+ + Q++++A +++ +QE + N+ Sbjct: 677 INECDEKLKKETGEKIKLNGQKGDLERELATANASAQQQKEATEFAQQQVQEKDARNK-- 734 Query: 829 VLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDL 888 L + ++K+ ++ +++ + +L + N+++ S + + L+E + Sbjct: 735 ELQNKINDLQKKANAADNLQQQVDQLKSMLDDANKSINDKDSQINEKQKELIETRKKASA 794 Query: 889 AE--SESTK-YQTQLRDLESNLKRITHEHQTL---IVQKKKEIEDLEIEFNTQIESAIRD 942 E +S K Q +L + +++L ++++ L + + KK+I DL E N ++ + D Sbjct: 795 LEPTKQSLKDTQAELTEKQNDLNNANNKNRELERELKELKKQIGDLNRE-NNDLKEQLDD 853 Query: 943 KKVLNEKYEKNIEYVTQLEAQLQEYKNN--IENLNMNVEELNKMNLELIDKHVQKQQTQS 1000 K ++ EK + + +L A++QE ++ ++N + E++N+ L+ + +++ + + Sbjct: 854 KVKNDDIIEKLRKQIDELNAKIQELQSQKPVDNSSALEEKINE--LQKAKQELEETENKL 911 Query: 1001 PDYTEQYI---NEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKL 1057 D T++ + E+ K N L+ D+ L + + A + ++D E+ ++ T+L Sbjct: 912 KDTTDELMAKDKELQKANRGLEHLDQ----LTRDLEVALAE--NKIADAEN--SELKTQL 963 Query: 1058 ENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKE-TKLTFEMN--IPKTEGMII 1114 N + E+Q+ + + +NE+L DD K+L + TK ++N + E ++ Sbjct: 964 ANKDNELQKAKQDNTRLQSNNEQL---TANSDDLNKKLTDATKDNIKLNGQVKDLERLLQ 1020 Query: 1115 SSTIEPMSDDANNVDXXXXXXXXXXXXLK-VQEEEEFIQERSVLQEQSAKLNTELQECYT 1173 S E + +V+ LK +Q + +Q+ +E+ L LQ Sbjct: 1021 SKEAE-LDQQNQSVEQLKSQVTDKDDKLKELQSKLNDLQKELSEKERLENLANSLQSKLD 1079 Query: 1174 KIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGF 1233 ++++ N +L + + ++Q+N+++ K ++L D L EL Q+ Sbjct: 1080 D--EIKSNNEKLNQLNEL-EKQMNEVQKKADKLQPTQDKLKYAQDELTEK------QKEL 1130 Query: 1234 EIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDS--VQSSTQEETNKIVTMEQ 1291 + + + L ++ D +K +L Q E + + + + V + +++ ++++ + Sbjct: 1131 DASNANNRDLQKQIKDLKKQNDDLDEQKQKLEEQLDNNVKAGDVIGNLRKQISELLAKNK 1190 Query: 1292 VTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXD 1351 +NK + +E L + + + NQ+E ++ ++E EK Sbjct: 1191 DLEAKNKDNNGDE-LAAKEAELESLKNQLEQIKKDLE-EKEEELKQVNDNLSAKDKELQK 1248 Query: 1352 LRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAE---AKVLELTHQ 1408 L EN+ ++Q+ + + N +N +L + + A+ ++ L + Sbjct: 1249 LSRENEKNSKLQKD-LEDANNQNKKLDDENNDLQSQLSTKDIELQKAQKEAGRLQNLVQK 1307 Query: 1409 LELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKE------SELAIL 1462 LE ++ ++Y K E T + N E N + +L + + EDL+ E E +E Sbjct: 1308 LEEQNKDLYNKLDEETAEKLKSNGEVRNAQLELAKTKANAEDLSKENEHLQEQNNEKDSF 1367 Query: 1463 RLKMHENANHYETMQKESEIERVK-LIEELNVKITE---SVSL-NKQVAELNKALEEEVA 1517 ++ AN E +K E E+++ I +LN +I E ++S N+ + +L K L E Sbjct: 1368 INELRAKAN--EAQKKAGENEKLQNQINDLNSQIDELNNAISAQNETINDLKKKLNEAQK 1425 Query: 1518 KTNE---MQTAL-----ENQEIE--IVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQG 1567 K N+ +Q +L EN E + I LN+++ N + + + +++ ++ K Sbjct: 1426 KANQVEPLQQSLSDAKEENNEKQEKIDELNEKLRNAEKQFKEADQRVKDLLTEQQRLKDS 1485 Query: 1568 RDEQLDNTMNKE 1579 D + ++ KE Sbjct: 1486 YDNINNMSLQKE 1497 Score = 173 bits (421), Expect = 3e-41 Identities = 331/1579 (20%), Positives = 664/1579 (42%), Gaps = 160/1579 (10%) Query: 91 SESLANTLKQKEILMEKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNT 150 +E L N+L L +++ ELSKR+ T D N Sbjct: 512 NEKLENSLDNANNL--SLQKGDELSKRNETLADLKKRNQELEARVRDLESQND-DEKDNE 568 Query: 151 IKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXX 210 + KD+ + L+ +++ + + D QE + + + AK+K Sbjct: 569 LAAKDSEIQNLKSQLEQTKKDLNDTQEDLKTANNDLSAKDKEIQKLKRDNEKIAKLNEDL 628 Query: 211 XEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLE 270 E ++ K++ ++++ D+ +L + KD + + + ++ E Sbjct: 629 KE-ANDEIKKLENEKDDLQSQLSDKDSKLQNAMREKDRANNENATLKQQINECDEKLKKE 687 Query: 271 HSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSL--EIAN-MTELTKK 327 + + L A+Q E + + +++EK + E+ N + +L KK Sbjct: 688 TGEKIK-LNGQKGDLERELATANASAQQQKEATEFAQQQVQEKDARNKELQNKINDLQKK 746 Query: 328 IELLEHLNCQIRQ-------TNKELENKLATMGTESKAVSSPSKKGSPLI-SRKSGRNTA 379 ++L Q+ Q NK + +K + + + K + KK S L +++S ++T Sbjct: 747 ANAADNLQQQVDQLKSMLDDANKSINDKDSQINEKQKELIETRKKASALEPTKQSLKDTQ 806 Query: 380 SKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXX 439 +++ + L+ N + + + E+ +L+ I LN++ D + + +K Sbjct: 807 AELTEKQNDLN----NANNKNRELERELKELKKQIGDLNRENNDLKEQLDDKVKNDDIIE 862 Query: 440 XXXXGKDTLIAQLQ-LEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQ---ELNDEIKD 495 D L A++Q L+ Q+ ++ S + E +NE+ K +++L++ +L D + Sbjct: 863 KLRKQIDELNAKIQELQSQKPVDNSSALE-----EKINELQKAKQELEETENKLKDTTDE 917 Query: 496 VNVKDL-IEKLKSAEEQITQLNDEI----------DAAN---KNMIKVKSNHKLKLKQ-- 539 + KD ++K E + QL ++ DA N K + K N K KQ Sbjct: 918 LMAKDKELQKANRGLEHLDQLTRDLEVALAENKIADAENSELKTQLANKDNELQKAKQDN 977 Query: 540 --MQKTIDNFSKVSDS-NKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYD-SGRMIE 595 +Q + + SD NK++ T++ L+ +V +LE + + L + S ++ Sbjct: 978 TRLQSNNEQLTANSDDLNKKLTDATKDNIKLNGQVKDLERLLQSKEAELDQQNQSVEQLK 1037 Query: 596 SDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEV----EDKLADISQLQ 651 S V K +++ L +++L + S+K L + LQ K D+ +KL +++L+ Sbjct: 1038 SQVTDKDDKLKEL-QSKLNDLQKELSEKERLENLANSLQSKLDDEIKSNNEKLNQLNELE 1096 Query: 652 SDQVCSEIKSVHLEEQIDALSASKKELALVIENL---KLDKEQLYGTIKDLENDKEDI-- 706 + K+ L+ D L ++ EL + L + L IKDL+ +D+ Sbjct: 1097 KQMNEVQKKADKLQPTQDKLKYAQDELTEKQKELDASNANNRDLQKQIKDLKKQNDDLDE 1156 Query: 707 -MNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIE 765 KL+ + N+ D + + ++ISELLAK N + ++K + G + +E +L E Sbjct: 1157 QKQKLEEQLDNNVKAGDVIGNLR-KQISELLAK-NKDLEAKNKDNNGDELAAKEAEL--E 1212 Query: 766 NIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVN 825 +++++L + K + EE + + D +L K +L +E +K S+ ++ N Sbjct: 1213 SLKNQLEQIKKDLEEKEEELKQVND---NLSAKDKELQKLSRENEKN-SKLQKDLEDANN 1268 Query: 826 RLAVLMDHDRVVEKQL----LEIEHENKE---LQKKNQILLEENQNLQISLSDMQQHY-- 876 + L D + ++ QL +E++ KE LQ Q L E+N++L L + Sbjct: 1269 QNKKLDDENNDLQSQLSTKDIELQKAQKEAGRLQNLVQKLEEQNKDLYNKLDEETAEKLK 1328 Query: 877 ------NALVE----KANRTDLA-ESESTKYQTQLRDLESN-LKRITHEHQTLIVQKKK- 923 NA +E KAN DL+ E+E + Q +D N L+ +E Q + +K Sbjct: 1329 SNGEVRNAQLELAKTKANAEDLSKENEHLQEQNNEKDSFINELRAKANEAQKKAGENEKL 1388 Query: 924 --EIEDLEI---EFNTQIES---AIRD-KKVLNEKYEKNIEYVTQLEAQLQEYKNNIENL 974 +I DL E N I + I D KK LNE +K V L+ L + K Sbjct: 1389 QNQINDLNSQIDELNNAISAQNETINDLKKKLNEA-QKKANQVEPLQQSLSDAKEENNEK 1447 Query: 975 NMNVEELNKMNLELIDKHVQKQQTQSPDY-TEQYI--NEINKLNALLKQKDEEIIALNQK 1031 ++ELN+ L +K ++ + D TEQ + + +N + QK++E+ + Sbjct: 1448 QEKIDELNE-KLRNAEKQFKEADQRVKDLLTEQQRLKDSYDNINNMSLQKEDELTKKENE 1506 Query: 1032 INNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQ 1091 ++ + + + D ++K K + E+ Q + KQL D+ + +L + E D+ Sbjct: 1507 VDTLKKA----LKDLQNKTNGSNDK--EIAEKEQELEKQLEDALR---DLSNVKSELDNA 1557 Query: 1092 IKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEE--EE 1149 ELK+ +++ N+ E + S E + ++ NN + L+ E + Sbjct: 1558 KNELKQLHSSYD-NL-NNEHKSLESEKEDLENELNNANSTINSKDKELSKLQRDNERLQN 1615 Query: 1150 FIQERSVLQEQSAKLNTELQ-------ECYTKIIQLETLNTELTGHDVVNQEQINQLKSK 1202 +E L++++ L+ E+Q + K+ + + N L + N L +K Sbjct: 1616 VNKENDDLKKENKSLDDEIQTLKNSNNDLNNKLQRAQRQNELLQAANDTLTNDNNDLNNK 1675 Query: 1203 LEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLS 1262 L ++ E N S ++++++++ E + Q L + D +L+ + + Sbjct: 1676 LTEVTKEKINADSLAKAAERELNNSINEK--EELKASNQQLTDQLNDLMNKNKDLKKKAN 1733 Query: 1263 AFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQ---NKLQDKE-----EHLRNLQEKYA 1314 + + + L+DS++S E K T+ Q T Q N+L D++ + L L +KY Sbjct: 1734 DAD-RLQNLVDSLKSQLAEAQKKANTVVQNTQPQPQSNELYDRQLEQLKQELEQLNDKYN 1792 Query: 1315 DVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEEN 1374 + + + + EK + + +++++Q +N N Sbjct: 1793 EAVQKYHDADNSARQEKQQHDLDNIKNNAAIQNKQETIENLEKQIQELEKQQNA-LNAAN 1851 Query: 1375 AQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRND-- 1432 + +K ++ D + K +L QL K E+ + L + N+ Sbjct: 1852 EEEQKQHKLDANKLQDALKKLKDEQEKNSDLEKQLIAKKDELGKANDRVKELLKENNNLK 1911 Query: 1433 -EFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEEL 1491 E +N + Y+ I L + +++L L+ + N +K + + V +E+ Sbjct: 1912 TEAKNNKDVSEFYQNEISMLDKDNKAKLEDLK-----DLNAKLAAEKAEKNKVVAALEQA 1966 Query: 1492 NV--KITESVS--LNKQVAELNK--------ALEEEVAK----TNEMQTALENQEIEIVT 1535 N K+ E + LNK++AEL A ++E K E+Q + E E Sbjct: 1967 NAANKVLEEANNELNKELAELQSRSDSGLPLAQKQEAEKLRNRVKELQDKVRGLEAEKRQ 2026 Query: 1536 LNDEITNLQNMVRASSSKI 1554 +ND++++LQ+ + +++S+I Sbjct: 2027 INDDVSDLQSKLDSANSEI 2045 Score = 169 bits (411), Expect = 5e-40 Identities = 290/1476 (19%), Positives = 613/1476 (41%), Gaps = 132/1476 (8%) Query: 147 LSNTIKEKDNALSVLQVKMKIMETTILDLQEKI-NEKDQIIEAKNKATTXXXXXXXXXXX 205 L+N ++ + N +LQ + DL +K+ + + I+A++KA T Sbjct: 327 LNNKLQREQNQNKLLQAANDTLTNDNNDLNDKLTSSNNDRIKAESKANTAERELINAIAE 386 Query: 206 XXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARF 265 E+ KQ ++ M +K E Q L D+E K + LE AN+ ++ Sbjct: 387 G-----EELKQTNKQLNGQLNEMNNNYK-ELQGKLNDLEKK---ANQLENANQRIQ---- 433 Query: 266 EISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELT 325 L QEL + L K++ + EK ++++ + +L Sbjct: 434 -------DLEQELAESQAESNGKDAKINELQKKANQLEPTEKKLVDKQNEND-----KLQ 481 Query: 326 KKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRK----SGRN-TAS 380 K+++ L+ Q+ + K EN++ + ++++ + + + L +K S RN T + Sbjct: 482 KELDELKDKYDQLEKALKAAENRVKELLSQNEKLENSLDNANNLSLQKGDELSKRNETLA 541 Query: 381 KMKSPWSQLSSETLNQDTDKKINK-NEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXX 439 +K +L + + ++ K NE+A + IQ+L L + +++ Sbjct: 542 DLKKRNQELEARVRDLESQNDDEKDNELAAKDSEIQNLKSQLEQTKKDLNDTQEDLKTAN 601 Query: 440 XXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEI--KDVN 497 KD I +L+ ++++ + + + ++ N+ K E K +L ++ KD Sbjct: 602 NDLSAKDKEIQKLKRDNEK------IAKLNEDLKEANDEIKKLENEKDDLQSQLSDKDSK 655 Query: 498 VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEI 557 +++ + + A + L +I+ ++ + K ++ K+KL + ++ +++ +N Sbjct: 656 LQNAMREKDRANNENATLKQQINECDEKL-KKETGEKIKLNGQKGDLER--ELATANASA 712 Query: 558 VRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAIS 617 + E Q+V E + LQ + D ++ +++ +++++ + K+I+ Sbjct: 713 QQQKEATEFAQQQVQEKDARNKELQNKINDLQKKANAADNLQQQVDQLKSMLDDANKSIN 772 Query: 618 LLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKE 677 +SQ + +EL ++K +E + Q++ E+Q D +A+ K Sbjct: 773 DKDSQINEKQKELIETRKKASALEPTKQSLKDTQAELT---------EKQNDLNNANNKN 823 Query: 678 LALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLA 737 L E +L K+ I DL + D+ +L + ++ N D+ +KL K +I EL A Sbjct: 824 RELERELKELKKQ-----IGDLNRENNDLKEQLDDKVK-NDDIIEKLRK----QIDELNA 873 Query: 738 KINH-EEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLE 796 KI + Q + ++ KI E ++ + EL + ++++ + + + Sbjct: 874 KIQELQSQKPVDNSSALEEKINE----LQKAKQELEETENKLKDTTDELMAKDKELQKAN 929 Query: 797 RKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQ 856 R + L ++ + A +E I + E L + D ++K + +N LQ N+ Sbjct: 930 RGLEHLDQLTRDLEVALAENKIADAENSELKTQLANKDNELQKA----KQDNTRLQSNNE 985 Query: 857 ILLEENQNLQISLSDMQQH---YNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHE 913 L + +L L+D + N V+ R L +S+ + Q + +E ++T + Sbjct: 986 QLTANSDDLNKKLTDATKDNIKLNGQVKDLER--LLQSKEAELDQQNQSVEQLKSQVTDK 1043 Query: 914 HQTLIVQKKKEIEDLEIEFNTQ--IESAIRD-KKVLNEKYEKNIEYVTQL---EAQLQEY 967 L + + ++ DL+ E + + +E+ + L+++ + N E + QL E Q+ E Sbjct: 1044 DDKL-KELQSKLNDLQKELSEKERLENLANSLQSKLDDEIKSNNEKLNQLNELEKQMNEV 1102 Query: 968 KNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYT-EQYINEINKLNALL---KQKDE 1023 + + L ++L EL +K + + + + ++ I ++ K N L KQK E Sbjct: 1103 QKKADKLQPTQDKLKYAQDELTEKQKELDASNANNRDLQKQIKDLKKQNDDLDEQKQKLE 1162 Query: 1024 EIIALNQKINNAQVSYMSMVSDYESKLAQFTTK-LENMEEEMQRVSKQLLDSKQHNEELQ 1082 E + N K + + +S+ +K K +N +E+ +L K E+++ Sbjct: 1163 EQLDNNVKAGDVIGNLRKQISELLAKNKDLEAKNKDNNGDELAAKEAELESLKNQLEQIK 1222 Query: 1083 ILVREQDDQIKELKETKLTFEMNIPK-TEGMIISSTIEPMSDDANNVDXXXXXXXX---X 1138 + E+++++K++ + + + K + +S ++ +DANN + Sbjct: 1223 KDLEEKEEELKQVNDNLSAKDKELQKLSRENEKNSKLQKDLEDANNQNKKLDDENNDLQS 1282 Query: 1139 XXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVN-QEQIN 1197 K E ++ +E LQ KL + ++ Y K+ + ET + +V N Q ++ Sbjct: 1283 QLSTKDIELQKAQKEAGRLQNLVQKLEEQNKDLYNKLDE-ETAEKLKSNGEVRNAQLELA 1341 Query: 1198 QLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHEL 1257 + K+ E L+ EN++L E + S +++ + E K+ A Q ++L Sbjct: 1342 KTKANAEDLSKENEHL----QEQNNEKDSFINELRAKANEAQKK--AGENEKLQNQINDL 1395 Query: 1258 RVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVI 1317 Q+ + +++ ++ QV LQ L D +E QEK D + Sbjct: 1396 NSQIDELNNAISAQNETINDLKKKLNEAQKKANQVEPLQQSLSDAKEENNEKQEKI-DEL 1454 Query: 1318 NQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQL 1377 N E LR+ + K A DL TE Q K + NIN + Q Sbjct: 1455 N--EKLRNAEKQFKEA------------DQRVKDLLTEQQRLKDSYD----NINNMSLQK 1496 Query: 1378 KKSSXXXXXXXXXXXXRVNDAEAKVLELTH-QLELKDSEIYQKTHEYTITLTQRNDEFEN 1436 + + D + K ++ K+ E+ ++ + L+ E +N Sbjct: 1497 EDELTKKENEVDTLKKALKDLQNKTNGSNDKEIAEKEQELEKQLEDALRDLSNVKSELDN 1556 Query: 1437 VRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKIT 1496 + +L + ++L E +S L + + N+ + + E KL + N ++ Sbjct: 1557 AKNELKQLHSSYDNLNNEHKS-LESEKEDLENELNNANSTINSKDKELSKLQRD-NERLQ 1614 Query: 1497 ESVSLNKQVAELNKALEEEVAK--------TNEMQTALENQEIEIVTLNDEITNLQNMVR 1548 N + + NK+L++E+ N++Q A E+ + ND +TN N + Sbjct: 1615 NVNKENDDLKKENKSLDDEIQTLKNSNNDLNNKLQRAQRQNEL-LQAANDTLTNDNNDLN 1673 Query: 1549 ASSSKIQKHVSFASDTKQGRDEQLDNTMN-KELLDA 1583 +++ K A + + +L+N++N KE L A Sbjct: 1674 NKLTEVTKEKINADSLAKAAERELNNSINEKEELKA 1709 Score = 162 bits (393), Expect = 8e-38 Identities = 225/1047 (21%), Positives = 458/1047 (43%), Gaps = 83/1047 (7%) Query: 570 KVAELEEEKGNLQLHLVDYDSGRMIE------SDVYKKMIEMENLAETRLKAIS--LLES 621 K A E K N QL ++ D I+ +D+ KK ++++ A +R+K + L ES Sbjct: 21 KAASEELAKTNEQLDNLNKDKDNKIKELQSKVNDLEKKSNQLDD-ANSRIKELEDELTES 79 Query: 622 Q--KFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELA 679 + K DL +L+ LQ+K +E++ K + Q + D S+ ++ ++++D L ++L Sbjct: 80 ETSKDDLSNKLNDLQKKLNELQKKANQLDQAKKDLADSQQENTEKQKEVDDLKTQLRDLE 139 Query: 680 LVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAE---KISELL 736 ++ L+ + L KDL+ ED M K ++ + + + L+K A+ K+ +L Sbjct: 140 KEMKQLQKKNDDLEKANKDLQEKLEDSM-KQESELSKKDQVLANLKKALADATNKVKDLE 198 Query: 737 AKINHEEQSKIQTQ----FGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRR 792 ++N I + + +++++ + N++SEL K+ + +L S + + Sbjct: 199 NQLNGSNDKDIAAKEREIESLKSQLEDALRDLSNVKSELDNAKNELKQLHSSYDNLNNEH 258 Query: 793 YSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRV--VEKQLLEIEHENKE 850 SLE + + L + E A S ++ EL + D++R+ V K+ +++ ENK Sbjct: 259 KSLESEKEDLEN---ELNNANSTINSKDKELSK---LQRDNERLQNVNKENDDLKKENKS 312 Query: 851 LQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESE--STKYQTQLRD-LESNL 907 L + Q L N +L L +Q+ N L++ AN T ++ + K + D +++ Sbjct: 313 LDDEIQTLKNSNNDLNNKL-QREQNQNKLLQAANDTLTNDNNDLNDKLTSSNNDRIKAES 371 Query: 908 KRITHEHQTL-IVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQE 966 K T E + + + + +E++ + N Q+ + K L K + QLE Q Sbjct: 372 KANTAERELINAIAEGEELKQTNKQLNGQLNEMNNNYKELQGKLNDLEKKANQLENANQR 431 Query: 967 YKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDE--- 1023 ++ + L + E N + ++ +QK+ Q ++ +++ N+ + L K+ DE Sbjct: 432 IQDLEQELAESQAESNGKDAKI--NELQKKANQLEPTEKKLVDKQNENDKLQKELDELKD 489 Query: 1024 EIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENME----EEMQRVSKQLLDSKQHNE 1079 + L + + A+ ++S E KL N+ +E+ + ++ L D K+ N+ Sbjct: 490 KYDQLEKALKAAENRVKELLSQNE-KLENSLDNANNLSLQKGDELSKRNETLADLKKRNQ 548 Query: 1080 ELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXX 1139 EL+ VR+ + Q + K+ +L + +E + S +E D N+ Sbjct: 549 ELEARVRDLESQNDDEKDNELAAK----DSEIQNLKSQLEQTKKDLNDTQ---EDLKTAN 601 Query: 1140 XXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQL 1199 L +++E IQ+ E+ AKLN +L+E +I +LE +L Q Q++ Sbjct: 602 NDLSAKDKE--IQKLKRDNEKIAKLNEDLKEANDEIKKLENEKDDL-------QSQLSDK 652 Query: 1200 KSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQH--LAQREADFQKTEHEL 1257 SKL+ E D + A L+ I+ ++ E E K + E + Sbjct: 653 DSKLQNAMREKDRANNENATLKQQINECDEKLKKETGEKIKLNGQKGDLERELATANASA 712 Query: 1258 RVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVI 1317 + Q A E +Q+ + + +E NKI +++ + + LQ + + L+++ + I Sbjct: 713 QQQKEATEFAQQQVQEK-DARNKELQNKINDLQKKANAADNLQQQVDQLKSMLDDANKSI 771 Query: 1318 N----QIEILRSE-IEDEKVAFX-----XXXXXXXXXXXXXXXDLRTENQSYKQMQEQSI 1367 N QI + E IE K A DL N +++ E+ + Sbjct: 772 NDKDSQINEKQKELIETRKKASALEPTKQSLKDTQAELTEKQNDLNNANNKNREL-EREL 830 Query: 1368 LNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIY-QKTHEYTIT 1426 + ++ L + + + +D K+ + +L K E+ QK + + Sbjct: 831 KELKKQIGDLNREN-NDLKEQLDDKVKNDDIIEKLRKQIDELNAKIQELQSQKPVDNSSA 889 Query: 1427 LTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVK 1486 L ++ +E + +Q+L E E +++D T E ++ L+ K + H + + ++ E+ Sbjct: 890 LEEKINELQKAKQELEETENKLKDTTDELMAKDKELQ-KANRGLEHLDQLTRDLEV---- 944 Query: 1487 LIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNM 1546 + E + E+ L Q+A NK + E+ K + T L++ ++ +D++ Sbjct: 945 ALAENKIADAENSELKTQLA--NK--DNELQKAKQDNTRLQSNNEQLTANSDDLNKKLTD 1000 Query: 1547 VRASSSKIQKHVSFASDTKQGRDEQLD 1573 + K+ V Q ++ +LD Sbjct: 1001 ATKDNIKLNGQVKDLERLLQSKEAELD 1027 Score = 154 bits (373), Expect = 2e-35 Identities = 248/1136 (21%), Positives = 490/1136 (43%), Gaps = 123/1136 (10%) Query: 502 IEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVS----DSNKEI 557 ++ K+A E++ + N+++D NK+ K N K+K++Q +++ K S D+N I Sbjct: 17 LQTAKAASEELAKTNEQLDNLNKD----KDN---KIKELQSKVNDLEKKSNQLDDANSRI 69 Query: 558 VRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAIS 617 L +EL +L + +LQ L + K + + + + K + Sbjct: 70 KELEDELTESETSKDDLSNKLNDLQKKLNELQKKANQLDQAKKDLADSQQENTEKQKEVD 129 Query: 618 LLESQKFDLVQELHILQQKYDEVE-------DKLADISQLQS-----DQVCSEIKSV--- 662 L++Q DL +E+ LQ+K D++E +KL D + +S DQV + +K Sbjct: 130 DLKTQLRDLEKEMKQLQKKNDDLEKANKDLQEKLEDSMKQESELSKKDQVLANLKKALAD 189 Query: 663 ------HLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQE 716 LE Q++ ++ K++A ++ K QL ++DL N K ++ N +N +++ Sbjct: 190 ATNKVKDLENQLN--GSNDKDIAAKEREIESLKSQLEDALRDLSNVKSELDN-AKNELKQ 246 Query: 717 NMDLTDKL--EKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKY 774 D L E S E E L + S I ++ +K+Q + ++N+ E Sbjct: 247 LHSSYDNLNNEHKSLESEKEDLENELNNANSTINSKDKELSKLQRDNERLQNVNKENDDL 306 Query: 775 KSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHD 834 K L++ I +++ L K + + + Q A T ++L ++L ++D Sbjct: 307 KKENKSLDDEIQTLKNSNNDLNNKLQREQNQNKLLQAANDTLTNDNNDLNDKL-TSSNND 365 Query: 835 RV--------VEKQLLEIEHENKELQKKNQIL---LEENQN----LQISLSDMQQHYNAL 879 R+ E++L+ E +EL++ N+ L L E N LQ L+D+++ N L Sbjct: 366 RIKAESKANTAERELINAIAEGEELKQTNKQLNGQLNEMNNNYKELQGKLNDLEKKANQL 425 Query: 880 VEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIE-S 938 R E E + Q + ++ + + + L +KK ++ Q E Sbjct: 426 ENANQRIQDLEQELAESQAESNGKDAKINELQKKANQLEPTEKKLVDKQNENDKLQKELD 485 Query: 939 AIRDKKVLNEKYEKNIE-YVTQLEAQLQEYKNNIENLN----MNVEELNKMNLELIDKHV 993 ++DK EK K E V +L +Q ++ +N+++N N +EL+K N L D Sbjct: 486 ELKDKYDQLEKALKAAENRVKELLSQNEKLENSLDNANNLSLQKGDELSKRNETLADLKK 545 Query: 994 QKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQF 1053 + Q+ ++ + N+ K N L KD EI L ++ + ++D + L Sbjct: 546 RNQELEARVRDLESQNDDEKDNE-LAAKDSEIQNLKSQLEQTKKD----LNDTQEDLKTA 600 Query: 1054 TTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMI 1113 L ++E+Q++ + + NE+L +E +D+IK+L+ K + + + + Sbjct: 601 NNDLSAKDKEIQKLKRDNEKIAKLNEDL----KEANDEIKKLENEKDDLQSQLSDKDSKL 656 Query: 1114 ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYT 1173 ++ E D ANN + +E E I+ + +L T Sbjct: 657 QNAMRE--KDRANNENATLKQQINECDEKLKKETGEKIKLNGQKGDLERELATANASAQQ 714 Query: 1174 KIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGF 1233 + E ++ D N+E N++ ++ N DNL V +L+S + A Sbjct: 715 QKEATEFAQQQVQEKDARNKELQNKINDLQKKANAA-DNLQQQVDQLKSMLDDANKSIND 773 Query: 1234 EIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVT 1293 + +++ ++ QK E R + SA E + L D+ Q+ E+ N + Sbjct: 774 KDSQINEK---------QKELIETRKKASALEPTKQSLKDT-QAELTEKQN------DLN 817 Query: 1294 SLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLR 1353 + NK ++ E L+ L+++ D+ + L+ ++ D+KV ++ Sbjct: 818 NANNKNRELERELKELKKQIGDLNRENNDLKEQL-DDKVKNDDIIEKLRKQIDELNAKIQ 876 Query: 1354 TENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKD 1413 E QS K + S L E+ +L+K+ + + E K+ + T +L KD Sbjct: 877 -ELQSQKPVDNSSAL--EEKINELQKAK-----------QELEETENKLKDTTDELMAKD 922 Query: 1414 SEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDL-TYEKESELAILRLKMHENANH 1472 E+ QK + L Q + E + E +I D E +++LA ++ + Sbjct: 923 KEL-QKANRGLEHLDQLTRDLE-----VALAENKIADAENSELKTQLANKDNELQKAKQD 976 Query: 1473 YETMQKESEIERVKLIEELNVKIT----ESVSLNKQVAELNKALEEEVAKTNEMQTALEN 1528 +Q +E + ++LN K+T +++ LN QV +L + L+ + A+ ++ ++E Sbjct: 977 NTRLQSNNE-QLTANSDDLNKKLTDATKDNIKLNGQVKDLERLLQSKEAELDQQNQSVEQ 1035 Query: 1529 QEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAV 1584 + ++ +D++ LQ+ + + +QK +S ++ R E L N++ +L D + Sbjct: 1036 LKSQVTDKDDKLKELQSKL----NDLQKELS-----EKERLENLANSLQSKLDDEI 1082 Score = 154 bits (373), Expect = 2e-35 Identities = 267/1327 (20%), Positives = 558/1327 (42%), Gaps = 105/1327 (7%) Query: 323 ELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKM 382 EL K E L++LN KEL++K+ + +S + + + L + T+ Sbjct: 26 ELAKTNEQLDNLNKDKDNKIKELQSKVNDLEKKSNQLDDANSRIKELEDELTESETSK-- 83 Query: 383 KSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXX 442 LS++ LN D KK+ NE+ K + KDL D + +EK Sbjct: 84 ----DDLSNK-LN-DLQKKL--NELQKKANQLDQAKKDLADSQQENTEKQKEVDDLKTQL 135 Query: 443 XGKDTLIAQLQLEHQQHMEGPSLIH--VGTNTEDVNEIAKVQEQLKQELNDEIKDV--NV 498 + + QLQ ++ + + + + + +E++K ++Q+ L + D V Sbjct: 136 RDLEKEMKQLQKKNDDLEKANKDLQEKLEDSMKQESELSK-KDQVLANLKKALADATNKV 194 Query: 499 KDLIEKLKSA--------EEQITQLNDEIDAANKNMIKVKS---NHKLKLKQMQKTIDNF 547 KDL +L + E +I L +++ A +++ VKS N K +LKQ+ + DN Sbjct: 195 KDLENQLNGSNDKDIAAKEREIESLKSQLEDALRDLSNVKSELDNAKNELKQLHSSYDNL 254 Query: 548 SKVSDS-NKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEME 606 + S E L EL++ + + ++E LQ + D+ K+ ++ Sbjct: 255 NNEHKSLESEKEDLENELNNANSTINSKDKELSKLQRDNERLQNVNKENDDLKKENKSLD 314 Query: 607 NLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLAD----ISQLQSDQVCSEIKSV 662 + +T + + L ++ + +LQ D + + D ++ +D++ +E K+ Sbjct: 315 DEIQTLKNSNNDLNNKLQREQNQNKLLQAANDTLTNDNNDLNDKLTSSNNDRIKAESKAN 374 Query: 663 HLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLE---NDKEDIMNKLQNYIQENMD 719 E ++ A +EL + L ++ K+L+ ND E N+L+N Q D Sbjct: 375 TAERELINAIAEGEELKQTNKQLNGQLNEMNNNYKELQGKLNDLEKKANQLENANQRIQD 434 Query: 720 LTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRIC 779 L +L + AE + AKIN E Q K + K+ ++ + ++ EL + K + Sbjct: 435 LEQELAESQAESNGK-DAKIN-ELQKKANQLEPTEKKLVDKQNENDKLQKELDELKDKYD 492 Query: 780 RLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEK 839 +LE+++ E+R L + ++L + L + + + LA L ++ +E Sbjct: 493 QLEKALKAAENRVKELLSQNEKLENSLDNANNLSLQKGDELSKRNETLADLKKRNQELEA 552 Query: 840 QLLEIEHENKELQKKNQILLEEN--QNLQISLSDMQQHYNALVE--KANRTDLAESESTK 895 ++ ++E +N + +K N++ +++ QNL+ L ++ N E K DL+ ++ + Sbjct: 553 RVRDLESQNDD-EKDNELAAKDSEIQNLKSQLEQTKKDLNDTQEDLKTANNDLS-AKDKE 610 Query: 896 YQTQLRDLE--SNLKRITHEHQTLIVQKKKEIEDLEIEF---NTQIESAIRDKKVLNEKY 950 Q RD E + L E I + + E +DL+ + ++++++A+R+K N + Sbjct: 611 IQKLKRDNEKIAKLNEDLKEANDEIKKLENEKDDLQSQLSDKDSKLQNAMREKDRANNEN 670 Query: 951 EKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQ-KQQTQSPDYTEQYIN 1009 + + + + +L+ K E + +N ++ + EL + +QQ ++ ++ +Q + Sbjct: 671 ATLKQQINECDEKLK--KETGEKIKLNGQK-GDLERELATANASAQQQKEATEFAQQQVQ 727 Query: 1010 EINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSK 1069 E + N L+ K ++ QK NA + V +S L + + + ++ K Sbjct: 728 EKDARNKELQNKINDL----QKKANAADNLQQQVDQLKSMLDDANKSINDKDSQINEKQK 783 Query: 1070 QLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVD 1129 +L+++++ L+ + D EL E + ++N + + ++ + +++ Sbjct: 784 ELIETRKKASALEPTKQSLKDTQAELTEKQ--NDLNNANNKNRELERELKELKKQIGDLN 841 Query: 1130 XXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKL-NTELQECYTKIIQLETLNTELTGH 1188 KV+ ++ + R + E +AK+ + Q+ LE EL Sbjct: 842 RENNDLKEQLDD-KVKNDDIIEKLRKQIDELNAKIQELQSQKPVDNSSALEEKINELQKA 900 Query: 1189 DVVNQEQINQLKSKLEQLNTENDNL------LSTVAELRSSISSAVDQRGFEIAE--LWK 1240 +E N+LK ++L ++ L L + +L + A+ + AE K Sbjct: 901 KQELEETENKLKDTTDELMAKDKELQKANRGLEHLDQLTRDLEVALAENKIADAENSELK 960 Query: 1241 QHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTME-QVTSLQNKL 1299 LA ++ + QK + + +L + + D + + T + + QV L+ L Sbjct: 961 TQLANKDNELQKAKQD-NTRLQSNNEQLTANSDDLNKKLTDATKDNIKLNGQVKDLERLL 1019 Query: 1300 QDKEEHL-------RNLQEKYADVINQIEILRSEIED---EKVAFXXXXXXXXXXXXXXX 1349 Q KE L L+ + D ++++ L+S++ D E Sbjct: 1020 QSKEAELDQQNQSVEQLKSQVTDKDDKLKELQSKLNDLQKELSEKERLENLANSLQSKLD 1079 Query: 1350 XDLRTENQSYKQMQ--EQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEA-KVLELT 1406 ++++ N+ Q+ E+ + + ++ +L+ + + + +A Sbjct: 1080 DEIKSNNEKLNQLNELEKQMNEVQKKADKLQPTQDKLKYAQDELTEKQKELDASNANNRD 1139 Query: 1407 HQLELKD--------SEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKE-- 1456 Q ++KD E QK E + D N+R+Q+ E + +DL + + Sbjct: 1140 LQKQIKDLKKQNDDLDEQKQKLEEQLDNNVKAGDVIGNLRKQISELLAKNKDLEAKNKDN 1199 Query: 1457 --SELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEE 1514 ELA ++ N E ++K+ E E+ + ++++N +L+ + EL K L Sbjct: 1200 NGDELAAKEAELESLKNQLEQIKKDLE-EKEEELKQVN------DNLSAKDKELQK-LSR 1251 Query: 1515 EVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASS---SKIQKHVSFASDTKQGRDEQ 1571 E K +++Q LE+ + L+DE +LQ+ + K QK + Q +EQ Sbjct: 1252 ENEKNSKLQKDLEDANNQNKKLDDENNDLQSQLSTKDIELQKAQKEAGRLQNLVQKLEEQ 1311 Query: 1572 LDNTMNK 1578 + NK Sbjct: 1312 NKDLYNK 1318 Score = 147 bits (357), Expect = 2e-33 Identities = 295/1455 (20%), Positives = 597/1455 (41%), Gaps = 169/1455 (11%) Query: 56 RAQKCLENAALVSKRIKEHRKATAELLGRPFVPGISESLANTLKQKEILMEKIKQYKELS 115 ++QK ++N++ + ++I E +KA EL E N LK + E + + KEL Sbjct: 879 QSQKPVDNSSALEEKINELQKAKQEL----------EETENKLK--DTTDELMAKDKELQ 926 Query: 116 KRSSTTIVRXXXXXXXXXXXXXXXQLGDV--THLSNTIKEKDNALSV-------LQVKMK 166 K ++ + ++ D + L + KDN L LQ + Sbjct: 927 K-ANRGLEHLDQLTRDLEVALAENKIADAENSELKTQLANKDNELQKAKQDNTRLQSNNE 985 Query: 167 IMETTILDLQEKINE--KDQI-IEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQE 223 + DL +K+ + KD I + + K E K Q+T + Sbjct: 986 QLTANSDDLNKKLTDATKDNIKLNGQVKDLERLLQSKEAELDQQNQSVEQLKSQVTDKDD 1045 Query: 224 NFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQ--ELEQX 281 ++++ D L K++ K+ R+ +L AN L EI + KL Q ELE+ Sbjct: 1046 KLKELQSKLND----LQKELSEKE-RLENL--ANSLQSKLDDEIKSNNEKLNQLNELEKQ 1098 Query: 282 XXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQT 341 + ++ + +E TE +++ AN +L K+I+ L+ N + + Sbjct: 1099 MNEVQKKADKLQP-TQDKLKYAQDELTEKQKELDASNANNRDLQKQIKDLKKQNDDLDEQ 1157 Query: 342 NKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKK 401 ++LE +L + + K+ S L+++ E N+D Sbjct: 1158 KQKLEEQLDNNVKAGDVIGNLRKQISELLAKNK---------------DLEAKNKDN--- 1199 Query: 402 INKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHME 461 N +E+A E ++SL L + + EK+ KD + +L E++++ + Sbjct: 1200 -NGDELAAKEAELESLKNQLEQIKKDLEEKEEELKQVNDNLSAKDKELQKLSRENEKNSK 1258 Query: 462 GPSLIHVGTNT----EDVNEIAKVQEQLKQ-ELNDEIKDVN-VKDLIEKLKSAEEQITQL 515 + N +D N + Q K EL K+ +++L++KL EEQ L Sbjct: 1259 LQKDLEDANNQNKKLDDENNDLQSQLSTKDIELQKAQKEAGRLQNLVQKL---EEQNKDL 1315 Query: 516 NDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELE 575 +++D K+KSN +++ Q++ + D +KE L E+ + + EL Sbjct: 1316 YNKLDEETAE--KLKSNGEVRNAQLELAKTK-ANAEDLSKENEHLQEQNNEKDSFINELR 1372 Query: 576 EEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQ 635 + Q + + + +D+ ++ E+ N + + I+ DL ++L+ Q+ Sbjct: 1373 AKANEAQKKAGENEKLQNQINDLNSQIDELNNAISAQNETIN-------DLKKKLNEAQK 1425 Query: 636 KYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQL--- 692 K ++VE +S + + + K L E++ KE +++L ++++L Sbjct: 1426 KANQVEPLQQSLSDAKEENNEKQEKIDELNEKLRNAEKQFKEADQRVKDLLTEQQRLKDS 1485 Query: 693 YGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKI-QTQF 751 Y I ++ KED + K +N + D L+K + +L K N +I + + Sbjct: 1486 YDNINNMSLQKEDELTKKENEV-------DTLKKA----LKDLQNKTNGSNDKEIAEKEQ 1534 Query: 752 GIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQK 811 ++ ++++ + N++SEL K+ + +L S + + SLE + + L + L Sbjct: 1535 ELEKQLEDALRDLSNVKSELDNAKNELKQLHSSYDNLNNEHKSLESEKEDLENELNNANS 1594 Query: 812 AYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSD 871 + +D+ +++L D++R L + EN +L+K+N+ L +E Q L+ S +D Sbjct: 1595 TINS----KDKELSKLQ--RDNER-----LQNVNKENDDLKKENKSLDDEIQTLKNSNND 1643 Query: 872 MQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIE 931 + N L + +L ++ + DL + L +T E + + E E Sbjct: 1644 LN---NKLQRAQRQNELLQAANDTLTNDNNDLNNKLTEVTKEK----INADSLAKAAERE 1696 Query: 932 FNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDK 991 N I + K N++ + + L++ N+ + L V+ L E K Sbjct: 1697 LNNSINEK-EELKASNQQLTDQLNDLMNKNKDLKKKANDADRLQNLVDSLKSQLAEAQKK 1755 Query: 992 -HVQKQQTQ-SPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESK 1049 + Q TQ P E Y ++ +L L+Q LN K N A Y Sbjct: 1756 ANTVVQNTQPQPQSNELYDRQLEQLKQELEQ-------LNDKYNEAVQKYHD-------- 1800 Query: 1050 LAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKT 1109 A + + E + ++ + + Q+ +E + + QI+EL++ + +N Sbjct: 1801 -ADNSARQEKQQHDLDNIKNNA--AIQNKQET---IENLEKQIQELEKQQNA--LNAANE 1852 Query: 1110 EGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQ 1169 E + DAN + K+++E+E + S L++Q EL Sbjct: 1853 EEQ------KQHKLDANKLQDALK---------KLKDEQE---KNSDLEKQLIAKKDELG 1894 Query: 1170 ECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVD 1229 + ++ +L N L N++ ++++ L+ +N L + +L + +++ Sbjct: 1895 KANDRVKELLKENNNLKTEAKNNKDVSEFYQNEISMLDKDNKAKLEDLKDLNAKLAAEKA 1954 Query: 1230 QRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTM 1289 ++ +A L + + A + ++ +EL +L+ +S+ + L Q ++E K+ Sbjct: 1955 EKNKVVAALEQANAANKV--LEEANNELNKELAELQSRSDSGLPLAQ---KQEAEKL--R 2007 Query: 1290 EQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXX 1349 +V LQ+K++ E R + + +D+ ++++ SEI D K Sbjct: 2008 NRVKELQDKVRGLEAEKRQINDDVSDLQSKLDSANSEIADLKQKLAAAQSALGEQQKKAE 2067 Query: 1350 XDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQL 1409 L+ N++ ++ Q+ I +N+ K+ ++ND E K E L Sbjct: 2068 DLLQKLNKAEQENQQ-----IQAQNSNESKNISDLAEKLKNLQKKLND-EMKEKE---AL 2118 Query: 1410 ELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYE---KESELAILRLKM 1466 + K S ++ + L Q+ +E ++++ QL E EK + DL + K E+ L+ ++ Sbjct: 2119 KSKLSAAEKEVSDLKSKLQQQTEENKDLKAQLAESEKNVNDLQSKLQAKNKEMDDLKQQL 2178 Query: 1467 HENANHYETMQKESE 1481 + A QK+ E Sbjct: 2179 SDAAQEVIAAQKKLE 2193 Score = 147 bits (357), Expect = 2e-33 Identities = 254/1237 (20%), Positives = 520/1237 (42%), Gaps = 126/1237 (10%) Query: 144 VTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXX 203 V L + + +KD+ L LQ K+ DLQ++++EK+++ N + Sbjct: 1033 VEQLKSQVTDKDDKLKELQSKLN-------DLQKELSEKERLENLANSLQSKLDDEIKSN 1085 Query: 204 XXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAA 263 E ++QM ++Q+ ++ +D+ + ++ K + + N+ L+ Sbjct: 1086 NEKLNQLNE-LEKQMNEVQKKADKLQPT-QDKLKYAQDELTEKQKELDASNANNRDLQKQ 1143 Query: 264 RFEISLEHSKL---AQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIAN 320 ++ ++ L Q+LE+ L KQ E + K ++E K N Sbjct: 1144 IKDLKKQNDDLDEQKQKLEEQLDNNVKAGDVIGNLRKQISELLAKNK-DLEAKNKDN--N 1200 Query: 321 MTELTKKIELLEHLNCQIRQTNKELENK----------LATMGTESKAVSSPSKKGSPLI 370 EL K LE L Q+ Q K+LE K L+ E + +S ++K S L Sbjct: 1201 GDELAAKEAELESLKNQLEQIKKDLEEKEEELKQVNDNLSAKDKELQKLSRENEKNSKLQ 1260 Query: 371 SR-KSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSL---NKDLVDKEY 426 + N K+ + L S+ +D + + + E +L+ ++Q L NKDL +K Sbjct: 1261 KDLEDANNQNKKLDDENNDLQSQLSTKDIELQKAQKEAGRLQNLVQKLEEQNKDLYNK-- 1318 Query: 427 VISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTED--VNEI-AKVQE 483 + E+ +A+ + + + + N +D +NE+ AK E Sbjct: 1319 -LDEETAEKLKSNGEVRNAQLELAKTKANAEDLSKENEHLQEQNNEKDSFINELRAKANE 1377 Query: 484 QLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKT 543 K+ +E + DL QI +LN+ I A N+ + +K K+ + Sbjct: 1378 AQKKAGENEKLQNQINDL-------NSQIDELNNAISAQNETINDLKKKLNEAQKKANQV 1430 Query: 544 IDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMI 603 +SD+ +E E++ L++K+ E++ + D + + D Y + Sbjct: 1431 EPLQQSLSDAKEENNEKQEKIDELNEKLRNAEKQFKEADQRVKDLLTEQQRLKDSYDNIN 1490 Query: 604 EMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDK-LADISQLQSDQVCSEIKSV 662 M E L + E++ L + L LQ K + DK +A+ Q Q+ ++ + Sbjct: 1491 NMSLQKEDEL---TKKENEVDTLKKALKDLQNKTNGSNDKEIAEKEQELEKQLEDALRDL 1547 Query: 663 -HLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLT 721 +++ ++D K+L +NL + K LE++KED+ N+L N ++ Sbjct: 1548 SNVKSELDNAKNELKQLHSSYDNLNNEH-------KSLESEKEDLENELNN-ANSTINSK 1599 Query: 722 DKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRL 781 DK E ++ +E L +N E + +D +IQ ++N ++L+ R R Sbjct: 1600 DK-ELSKLQRDNERLQNVNKENDDLKKENKSLDDEIQT----LKNSNNDLNNKLQRAQRQ 1654 Query: 782 EESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQL 841 E + D +L + L + L E K I D L + E++L Sbjct: 1655 NELLQAAND---TLTNDNNDLNNKLTEVTKE----KINADSLA----------KAAEREL 1697 Query: 842 LEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLR 901 +E +EL+ NQ L + L+D+ L +KAN D + Q + Sbjct: 1698 NNSINEKEELKASNQQLTD-------QLNDLMNKNKDLKKKANDAD-------RLQNLVD 1743 Query: 902 DLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIE--YVTQ 959 L+S L + T++ + + + E+ ++ Q+E ++ + LN+KY + ++ + Sbjct: 1744 SLKSQLAEAQKKANTVVQNTQPQPQSNEL-YDRQLEQLKQELEQLNDKYNEAVQKYHDAD 1802 Query: 960 LEAQLQEYKNNIENLNMNVEELNKM-NLELIDKHVQ---KQQ----TQSPDYTEQYINEI 1011 A+ ++ +++++N+ N NK +E ++K +Q KQQ + + +Q+ + Sbjct: 1803 NSARQEKQQHDLDNIKNNAAIQNKQETIENLEKQIQELEKQQNALNAANEEEQKQHKLDA 1862 Query: 1012 NKL-NALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQ 1070 NKL +AL K KDE+ N + ++ + ++ + + N++ E + +K Sbjct: 1863 NKLQDALKKLKDEQ--EKNSDLEKQLIAKKDELGKANDRVKELLKENNNLKTEAKN-NKD 1919 Query: 1071 LLDSKQHNEELQILVREQDDQIKELKE--TKLTFE------MNIPKTEGMIISSTIEPMS 1122 + S+ + E+ +L ++ ++++LK+ KL E + + + +E + Sbjct: 1920 V--SEFYQNEISMLDKDNKAKLEDLKDLNAKLAAEKAEKNKVVAALEQANAANKVLEEAN 1977 Query: 1123 DDANNVDXXXXXXXXXXXXLKVQEEEEFIQER-SVLQEQSAKLNTELQECYTKIIQLETL 1181 ++ N L ++E E ++ R LQ++ L E ++ + L++ Sbjct: 1978 NELNKELAELQSRSDSGLPLAQKQEAEKLRNRVKELQDKVRGLEAEKRQINDDVSDLQSK 2037 Query: 1182 NTELTGHDVVNQEQINQLKSKL-EQLNTENDNL--LSTVAELRSSISSAVDQRGFEIAEL 1238 ++++ +S L EQ D L L+ + I + I++L Sbjct: 2038 LDSANSEIADLKQKLAAAQSALGEQQKKAEDLLQKLNKAEQENQQIQAQNSNESKNISDL 2097 Query: 1239 WK--QHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETN---KIVTMEQ-V 1292 + ++L ++ D K + L+ +LSA E + L +Q T+E + ++ E+ V Sbjct: 2098 AEKLKNLQKKLNDEMKEKEALKSKLSAAEKEVSDLKSKLQQQTEENKDLKAQLAESEKNV 2157 Query: 1293 TSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIED 1329 LQ+KLQ K + + +L+++ +D ++ + ++E+ Sbjct: 2158 NDLQSKLQAKNKEMDDLKQQLSDAAQEVIAAQKKLEE 2194 Score = 144 bits (349), Expect = 2e-32 Identities = 232/1205 (19%), Positives = 518/1205 (42%), Gaps = 120/1205 (9%) Query: 140 QLGDVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXX 199 QL ++ N +++K + L Q K+K Q+++ EK + ++A N A Sbjct: 1091 QLNELEKQMNEVQKKADKLQPTQDKLKYA-------QDELTEKQKELDASN-ANNRDLQK 1142 Query: 200 XXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKL 259 ++ KQ++ + +N + + ++ + ++ +K+ + + + N Sbjct: 1143 QIKDLKKQNDDLDEQKQKLEEQLDNNVKA-GDVIGNLRKQISELLAKNKDLEAKNKDNNG 1201 Query: 260 LEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIA 319 E A E LE L +LEQ + + + K + +K S E Sbjct: 1202 DELAAKEAELE--SLKNQLEQIKKDLEEKEEEL-----KQVNDNLSAKDKELQKLSRENE 1254 Query: 320 NMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTA 379 ++L K +E + N ++ N +L+++L+T E + + + L+ + +N Sbjct: 1255 KNSKLQKDLEDANNQNKKLDDENNDLQSQLSTKDIELQKAQKEAGRLQNLVQKLEEQN-- 1312 Query: 380 SKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXX 439 + + + ++E L + + + + E+AK + + L+K+ + +EKD+ Sbjct: 1313 KDLYNKLDEETAEKLKSNGEVRNAQLELAKTKANAEDLSKENEHLQEQNNEKDSFINELR 1372 Query: 440 XXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQ----LKQELNDEIKD 495 AQ + + ++ + + + +++N Q + LK++LN+ K Sbjct: 1373 AKANE-----AQKKAGENEKLQN-QINDLNSQIDELNNAISAQNETINDLKKKLNEAQKK 1426 Query: 496 VN-VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSN 554 N V+ L + L A+E+ + ++ID N+ + + K ++++ + ++ DS Sbjct: 1427 ANQVEPLQQSLSDAKEENNEKQEKIDELNEKLRNAEKQFKEADQRVKDLLTEQQRLKDSY 1486 Query: 555 KEIVRLT-EELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRL 613 I ++ ++ L++K E++ K L+ L + +G + ++ +K E+E E L Sbjct: 1487 DNINNMSLQKEDELTKKENEVDTLKKALK-DLQNKTNGSN-DKEIAEKEQELEKQLEDAL 1544 Query: 614 KAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHL-----EEQI 668 + +S ++S+ + EL L YD + ++ + + D + +E+ + + ++++ Sbjct: 1545 RDLSNVKSELDNAKNELKQLHSSYDNLNNEHKSLESEKED-LENELNNANSTINSKDKEL 1603 Query: 669 DALSASKKELALVI---ENLKLDKEQLYGTIKDLENDKEDIMNKLQN------------- 712 L + L V ++LK + + L I+ L+N D+ NKLQ Sbjct: 1604 SKLQRDNERLQNVNKENDDLKKENKSLDDEIQTLKNSNNDLNNKLQRAQRQNELLQAAND 1663 Query: 713 -YIQENMDLTDKLEKMSAEKIS----------ELLAKINHEEQSKIQTQFGIDAKIQERD 761 +N DL +KL +++ EKI+ EL IN +E+ K Q D Q D Sbjct: 1664 TLTNDNNDLNNKLTEVTKEKINADSLAKAAERELNNSINEKEELKASNQQLTD---QLND 1720 Query: 762 LYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQED 821 L +N +L K + RL+ + ++ + ++KA+ + Q + ++ Y Q + Sbjct: 1721 LMNKN--KDLKKKANDADRLQNLVDSLKSQLAEAQKKANTVVQNTQPQPQSNELYDRQLE 1778 Query: 822 ELVNRLAVLMD-HDRVVEKQLLEIEHENKELQKKNQILLEEN---QNLQISLSDMQQHYN 877 +L L L D ++ V+K +E Q+ + ++ N QN Q ++ ++++ Sbjct: 1779 QLKQELEQLNDKYNEAVQKYHDADNSARQEKQQHDLDNIKNNAAIQNKQETIENLEKQIQ 1838 Query: 878 ALVEKANRTDLA-ESESTKYQTQLRDLESNLKRITHEHQT------LIVQKKKEIEDLE- 929 L ++ N + A E E +++ L+ LK++ E + ++ KK E+ Sbjct: 1839 ELEKQQNALNAANEEEQKQHKLDANKLQDALKKLKDEQEKNSDLEKQLIAKKDELGKAND 1898 Query: 930 -----IEFNTQIESAIRDKKVLNEKYEKNIEYVTQ-LEAQLQEYKNNIENLNMNVEELNK 983 ++ N +++ ++ K ++E Y+ I + + +A+L++ K+ L E NK Sbjct: 1899 RVKELLKENNNLKTEAKNNKDVSEFYQNEISMLDKDNKAKLEDLKDLNAKLAAEKAEKNK 1958 Query: 984 MNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQK-----INNAQVS 1038 + L +Q + E+ NE+NK A L+ + + + L QK + N Sbjct: 1959 VVAAL------EQANAANKVLEEANNELNKELAELQSRSDSGLPLAQKQEAEKLRNRVKE 2012 Query: 1039 YMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKET 1098 V E++ Q + +++ ++ + ++ D KQ Q + EQ + ++L + Sbjct: 2013 LQDKVRGLEAEKRQINDDVSDLQSKLDSANSEIADLKQKLAAAQSALGEQQKKAEDLLQ- 2071 Query: 1099 KLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQ 1158 ++N + E I + S+++ N+ K+ +E ++E+ L+ Sbjct: 2072 ----KLNKAEQENQQIQAQ---NSNESKNISDLAEKLKNLQK--KLNDE---MKEKEALK 2119 Query: 1159 EQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVA 1218 + + E+ + +K+ Q N +L +++ +N L+SKL+ N E D+L ++ Sbjct: 2120 SKLSAAEKEVSDLKSKLQQQTEENKDLKAQLAESEKNVNDLQSKLQAKNKEMDDLKQQLS 2179 Query: 1219 ELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSS 1278 + + +A Q+ E AE Q +D ++ ++ + ++K Q + + Sbjct: 2180 DAAQEVIAA--QKKLEEAE------RQESSDIDVVARDIEIENESDDNKPPQTITEDEEM 2231 Query: 1279 TQEET 1283 T +T Sbjct: 2232 TLLKT 2236 Score = 126 bits (304), Expect = 5e-27 Identities = 193/944 (20%), Positives = 409/944 (43%), Gaps = 77/944 (8%) Query: 665 EEQIDALSASKKELALV---IENLKLDKEQLYGTIKDLEN---DKEDIMNKLQNYIQENM 718 + ++ A+ +ELA ++NL DK+ IK+L++ D E N+L + Sbjct: 14 DRELQTAKAASEELAKTNEQLDNLNKDKDN---KIKELQSKVNDLEKKSNQLDDANSRIK 70 Query: 719 DLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRI 778 +L D+L + K +L K+N + Q K+ ++ + + + + E ++ + + Sbjct: 71 ELEDELTESETSK-DDLSNKLN-DLQKKLNELQKKANQLDQAKKDLADSQQENTEKQKEV 128 Query: 779 CRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVE 838 L+ + +E L++K D L ++ Q+ + QE EL + VL + ++ Sbjct: 129 DDLKTQLRDLEKEMKQLQKKNDDLEKANKDLQEKLEDSMKQESELSKKDQVLAN----LK 184 Query: 839 KQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQT 898 K L + ++ K+L+ NQ+ ++++ +++ + L + +SE + Sbjct: 185 KALADATNKVKDLE--NQLNGSNDKDIAAKEREIESLKSQLEDALRDLSNVKSELDNAKN 242 Query: 899 QLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVT 958 +L+ L S+ + +EH++L + E EDLE E N S I K K +++ E + Sbjct: 243 ELKQLHSSYDNLNNEHKSL----ESEKEDLENELN-NANSTINSKDKELSKLQRDNERLQ 297 Query: 959 QLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQS---PDYTEQYINEINKLN 1015 + + + K ++L+ ++ L N +L +K +Q++Q Q+ + N+ N LN Sbjct: 298 NVNKENDDLKKENKSLDDEIQTLKNSNNDLNNK-LQREQNQNKLLQAANDTLTNDNNDLN 356 Query: 1016 ALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSK 1075 L + + I K N A+ ++ +++ E +L Q +L EM K+L Sbjct: 357 DKLTSSNNDRIKAESKANTAERELINAIAEGE-ELKQTNKQLNGQLNEMNNNYKELQGKL 415 Query: 1076 QHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVD-XXXXX 1134 E+ + + +I++L++ E+ + E + I + AN ++ Sbjct: 416 NDLEKKANQLENANQRIQDLEQ-----ELAESQAESNGKDAKINELQKKANQLEPTEKKL 470 Query: 1135 XXXXXXXLKVQEEEEFIQERSVLQEQSAK-LNTELQECYTKIIQLETLNTELTGHDVVNQ 1193 K+Q+E + ++++ E++ K ++E ++ +LE + Sbjct: 471 VDKQNENDKLQKELDELKDKYDQLEKALKAAENRVKELLSQNEKLENSLDNANNLSLQKG 530 Query: 1194 EQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQ----RGFEIAELWKQHLAQREAD 1249 +++++ L L N L + V +L S D + EI L K L Q + D Sbjct: 531 DELSKRNETLADLKKRNQELEARVRDLESQNDDEKDNELAAKDSEIQNL-KSQLEQTKKD 589 Query: 1250 FQKTEHELRV---QLSAFESKYEQL------LDSVQSSTQEETNKIVTME-QVTSLQNKL 1299 T+ +L+ LSA + + ++L + + +E ++I +E + LQ++L Sbjct: 590 LNDTQEDLKTANNDLSAKDKEIQKLKRDNEKIAKLNEDLKEANDEIKKLENEKDDLQSQL 649 Query: 1300 QDKEEHLRNLQEKYADVINQIEILRSEIE--DEKV-AFXXXXXXXXXXXXXXXXDLRTEN 1356 DK+ L+N + N+ L+ +I DEK+ +L T N Sbjct: 650 SDKDSKLQNAMREKDRANNENATLKQQINECDEKLKKETGEKIKLNGQKGDLERELATAN 709 Query: 1357 QSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEI 1416 S +Q +E + ++ Q K + ++ND + K L+ + ++ Sbjct: 710 ASAQQQKEAT--EFAQQQVQEKDA------RNKELQNKINDLQKKA-NAADNLQQQVDQL 760 Query: 1417 YQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETM 1476 + ++ ++ + +++L+E K+ L K+S L + ++ E N Sbjct: 761 KSMLDDANKSINDKDSQINEKQKELIETRKKASALEPTKQS-LKDTQAELTEKQNDLNNA 819 Query: 1477 -QKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVT 1535 K E+ER ++EL +I + LN++ +L + L+++V K +++ +E +I Sbjct: 820 NNKNRELERE--LKELKKQIGD---LNRENNDLKEQLDDKV-KNDDI---IEKLRKQIDE 870 Query: 1536 LNDEITNLQNMVRA-SSSKIQKHVSFASDTKQGRDEQLDNTMNK 1578 LN +I LQ+ +SS +++ ++ KQ +L+ T NK Sbjct: 871 LNAKIQELQSQKPVDNSSALEEKINELQKAKQ----ELEETENK 910 Score = 110 bits (265), Expect = 3e-22 Identities = 173/838 (20%), Positives = 373/838 (44%), Gaps = 101/838 (12%) Query: 801 QLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLE 860 +LGS + + +EL L + ++ + ++ E++ + +L+KK+ L + Sbjct: 5 KLGSQAKAADRELQTAKAASEELAKTNEQLDNLNKDKDNKIKELQSKVNDLEKKSNQLDD 64 Query: 861 EN-----------------QNLQISLSDMQQHYNALVEKAN-----RTDLAES--ESTKY 896 N +L L+D+Q+ N L +KAN + DLA+S E+T+ Sbjct: 65 ANSRIKELEDELTESETSKDDLSNKLNDLQKKLNELQKKANQLDQAKKDLADSQQENTEK 124 Query: 897 QTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEY 956 Q ++ DL++ L+ + E + L QKK +DLE + N ++ + D + K + Sbjct: 125 QKEVDDLKTQLRDLEKEMKQL--QKKN--DDLE-KANKDLQEKLEDSMKQESELSKKDQV 179 Query: 957 VTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNA 1016 + L+ L + N +++L + N ++ ++ ++ ++Q D N ++L+ Sbjct: 180 LANLKKALADATNKVKDLENQLNGSNDKDIAAKEREIESLKSQLEDALRDLSNVKSELDN 239 Query: 1017 LLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEE---MQRVSKQLLD 1073 K + +++ + +NN S S D E++L + + + ++E +QR +++L + Sbjct: 240 -AKNELKQLHSSYDNLNNEHKSLESEKEDLENELNNANSTINSKDKELSKLQRDNERLQN 298 Query: 1074 SKQHNEELQILVREQDDQIKELKETK--LTFEMNIPKTEGMIISSTIEPMSDDANNVDXX 1131 + N++L+ + DD+I+ LK + L ++ + + ++ + + +++D N+++ Sbjct: 299 VNKENDDLKKENKSLDDEIQTLKNSNNDLNNKLQREQNQNKLLQAANDTLTNDNNDLNDK 358 Query: 1132 XXXXXXXXXXLKVQ---EEEEFIQ---ERSVLQEQSAKLNTELQECYTKIIQLE-TLN-T 1183 + + E E I E L++ + +LN +L E +L+ LN Sbjct: 359 LTSSNNDRIKAESKANTAERELINAIAEGEELKQTNKQLNGQLNEMNNNYKELQGKLNDL 418 Query: 1184 ELTGHDVVNQEQ-INQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQH 1242 E + + N Q I L+ +L + E++ + + EL+ + + + + Sbjct: 419 EKKANQLENANQRIQDLEQELAESQAESNGKDAKINELQKKANQLEPTEKKLVDKQNEND 478 Query: 1243 LAQREADFQKTEH-ELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQ--NKL 1299 Q+E D K ++ +L L A E++ ++LL S E+ + SLQ ++L Sbjct: 479 KLQKELDELKDKYDQLEKALKAAENRVKELL-----SQNEKLENSLDNANNLSLQKGDEL 533 Query: 1300 QDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSY 1359 + E L +L+++ ++ ++ L S+ +DEK D +E Q+ Sbjct: 534 SKRNETLADLKKRNQELEARVRDLESQNDDEK------------DNELAAKD--SEIQNL 579 Query: 1360 KQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQK 1419 K EQ+ ++N+ LK ++ ND AK E+ Q +D+E K Sbjct: 580 KSQLEQTKKDLNDTQEDLKTAN--------------NDLSAKDKEI--QKLKRDNEKIAK 623 Query: 1420 THEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELA-ILRLKMHENANHYETMQK 1478 +E L + NDE + + + + + ++ D K+S+L +R K N + Q+ Sbjct: 624 LNE---DLKEANDEIKKLENEKDDLQSQLSD----KDSKLQNAMREKDRANNENATLKQQ 676 Query: 1479 ESEIERVKLIEELNVKIT---ESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVT 1535 +E + KL +E KI + L +++A N + +++ T Q ++ ++ Sbjct: 677 INECDE-KLKKETGEKIKLNGQKGDLERELATANASAQQQKEATEFAQQQVQEKDARNKE 735 Query: 1536 LNDEITNLQNMVRASSS------KIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRA 1587 L ++I +LQ A+ + +++ + A+ + +D Q+ N KEL++ +A Sbjct: 736 LQNKINDLQKKANAADNLQQQVDQLKSMLDDANKSINDKDSQI-NEKQKELIETRKKA 792 Score = 79.0 bits (186), Expect = 1e-12 Identities = 127/621 (20%), Positives = 245/621 (39%), Gaps = 38/621 (6%) Query: 981 LNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYM 1040 + K+ L K ++ + +E+ +L+ L K KD +I L K+N+ + Sbjct: 1 MEKLKLGSQAKAADRELQTAKAASEELAKTNEQLDNLNKDKDNKIKELQSKVNDLE-KKS 59 Query: 1041 SMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKL 1100 + + D S++ + +L E +S +L D ++ ELQ + D K+L +++ Sbjct: 60 NQLDDANSRIKELEDELTESETSKDDLSNKLNDLQKKLNELQKKANQLDQAKKDLADSQQ 119 Query: 1101 TFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQ 1160 E + E + + + + + + L+ + E+ QE + ++ Sbjct: 120 --ENTEKQKEVDDLKTQLRDLEKEMKQLQKKNDDLEKANKDLQEKLEDSMKQESELSKKD 177 Query: 1161 S--AKLNTELQECYTKIIQLETLNTELTGHDVVNQE-QINQLKSKLEQLNTENDNLLSTV 1217 A L L + K+ LE D+ +E +I LKS+LE + N+ S + Sbjct: 178 QVLANLKKALADATNKVKDLENQLNGSNDKDIAAKEREIESLKSQLEDALRDLSNVKSEL 237 Query: 1218 AELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQS 1277 ++ + Q L +H E++ + E+EL S SK ++ L +Q Sbjct: 238 DNAKNELK----QLHSSYDNLNNEH-KSLESEKEDLENELNNANSTINSK-DKELSKLQR 291 Query: 1278 STQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXX 1337 + N + + L D+ + L+N + + + + ++ Sbjct: 292 DNERLQNVNKENDDLKKENKSLDDEIQTLKNSNNDLNNKLQREQNQNKLLQAANDTLTND 351 Query: 1338 XXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVND 1397 D R + +S E+ ++N E +LK+++ + Sbjct: 352 NNDLNDKLTSSNND-RIKAESKANTAERELINAIAEGEELKQTNKQLNGQLNEMNNNYKE 410 Query: 1398 AEAKVLEL---THQLELKDSEIYQKTHEYTITLTQRN------DEFENVRQQLVEYEKRI 1448 + K+ +L +QLE + I E + + N +E + QL EK++ Sbjct: 411 LQGKLNDLEKKANQLENANQRIQDLEQELAESQAESNGKDAKINELQKKANQLEPTEKKL 470 Query: 1449 EDLTYEKESELAILRLKMHENANHYETMQK--ESEIERVKLIEELNVKITESVSLNKQVA 1506 D K++E L+ ++ E + Y+ ++K ++ RVK + N K+ S+ N Sbjct: 471 VD----KQNENDKLQKELDELKDKYDQLEKALKAAENRVKELLSQNEKLENSLD-NANNL 525 Query: 1507 ELNKALEEEVAKTNEMQTALE--NQEIEIVTLNDEITN---LQNMVRASSSKIQKHVSFA 1561 L K +E++K NE L+ NQE+E + E N N + A S+IQ S Sbjct: 526 SLQKG--DELSKRNETLADLKKRNQELEARVRDLESQNDDEKDNELAAKDSEIQNLKSQL 583 Query: 1562 SDTKQG-RDEQLD-NTMNKEL 1580 TK+ D Q D T N +L Sbjct: 584 EQTKKDLNDTQEDLKTANNDL 604 >UniRef50_A2DKP8 Cluster: Viral A-type inclusion protein, putative; n=1; Trichomonas vaginalis G3|Rep: Viral A-type inclusion protein, putative - Trichomonas vaginalis G3 Length = 1618 Score = 178 bits (434), Expect = 9e-43 Identities = 285/1357 (21%), Positives = 604/1357 (44%), Gaps = 132/1357 (9%) Query: 213 DTK-QQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271 DT+ QQ+ Q N I+ + ++ + L +D + S ++ N +++ + E+S Sbjct: 252 DTELQQLRSNQNNNISNLIQSQNNQYSLKEDNKDSQELSSQIQNLNSMVQKLQNELS--E 309 Query: 272 SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEE-KTEIEEKGSLEIA---NMTELTKK 327 SKL E K +E K ++E+ + A N +L + Sbjct: 310 SKLLNEQNSSKIDELNALNNSLIDEKSRLESELSNAKAKVEQSNTNSSAMAQNNAKLQEL 369 Query: 328 IELLEHLNCQIRQTNKELENKL----ATMGTESKAVSSPSKKGSPLISRKSGRNTA---- 379 E+++ L + Q K+L++++ A + S+ + S++ S L NT Sbjct: 370 NEMIQKLTNEKNQLEKDLKSQIEQDKAKLNELSQQNNKISEEKSQLQKIYEQNNTKMQEL 429 Query: 380 -SKMKSPWSQLSS-ETLNQDTDKKIN--KNEIAKLEMVIQSLNKDL-VDKEYVISEKDTX 434 K+ + ++++ LNQ +N K++ K +Q LN++L +K +++ + + Sbjct: 430 NQKLANSEAKINDLNALNQKISGDLNNSKSQKEKESSKLQQLNQNLSEEKAFILQQLNET 489 Query: 435 XXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTED--VNEIAKVQEQLKQELNDE 492 D +L+ + + + I ++ + I+K++++ K +L + Sbjct: 490 KISMQNLMEENDHFSNELKQSKSLNDQNNAKIKELSDQKSQLQTNISKLEKE-KSDLISK 548 Query: 493 IKDVN--VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHK-----LKLKQMQKTID 545 + DVN V+ +KL+S + QL +E+ A+K++I+ +SN K K+ Q+Q ++ Sbjct: 549 LNDVNKLVEQSSQKLQSNNNEKLQLENEL-KASKSLIE-QSNIKEQELNQKISQIQNQLN 606 Query: 546 NF-SKVSDSNKEIVRLTEE---LHHLSQKVAELEEEKGNLQ-LHLVDYDSGRMIES---- 596 N +K+ + ++ I+ L E L + QK E E NLQ + ++ + +I+S Sbjct: 607 NSNAKIQELSENIMNLKSENAKLREMKQKSEENSENNINLQKIEEMNREKEELIKSYNDK 666 Query: 597 --DVYKKMIEMENLAETRLKAISLLESQKFDLVQELH-----ILQQKYDEVEDKLADISQ 649 ++ I++ N IS L+++K ++ + + +QK + +E +I Sbjct: 667 IDNMTNDSIQLVNQISELKNTISKLQNEKIEIQNRMKREVSAVTEQKNESIERLQQEI-- 724 Query: 650 LQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIK-DLENDKEDIMN 708 L+ D + +E KS ++ E ++ L+ +E N LD ++ + +K + E K+D N Sbjct: 725 LKKDGIINEQKS-NISE-LEQLALQLQE----ENNTFLDSKEEFDKLKEEYEKMKQDSNN 778 Query: 709 KLQNYIQENM-DLTDKLEK-----MSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDL 762 N +++N+ LT L+K +A+ +E L + N+ +Q I ID+ Q + Sbjct: 779 PKINELEQNVKQLTKALQKTLNDLKAAKSENEQLLQSNNSDQKIISLNKKIDSLNQSIND 838 Query: 763 YIENIESELS-------KYKSRICRL-----EESIAVMEDRRY--SLERKADQLGSYLQE 808 Y E ++ S KY+ +I ++ E+++ + E + LE++ +L + L E Sbjct: 839 YEETTKALASENYEITQKYEQQINQISNQLNEKNVLLQEKEKQINDLEQENKELNNQLNE 898 Query: 809 KQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQIS 868 Q+ E + + +N L + + + V Q++E++ ENKEL N L E Q + S Sbjct: 899 MQQDKEEKEERYQQQINDLQKISNEQQNV--QIIELQTENKEL---NNQLNEMQQIKEKS 953 Query: 869 LSDMQQHYNALV-EKANRTDLAESESTKYQTQLRDLESNLKRI-----THEHQTLIVQKK 922 ++ Q+ N L+ K+N +++ ES K Q ++ + K+I T ++ I+ + Sbjct: 954 EAEYQKQINDLLSNKSNNSEMIESLRRKLQQNEEEITNYKKQINELNNTKQNNEEIINYQ 1013 Query: 923 KEIEDLEIEFN--TQIESAIRD-KKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVE 979 K+I +L+ E N Q I + KK + E +++ E V + Q+++ KN + +L N + Sbjct: 1014 KQINELKKELNITKQNNDLIANYKKQIEELSKQSNEEVVNYQKQVEDLKNKLIDLQQNNQ 1073 Query: 980 ELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSY 1039 E+ K + ID+ + ++++ S + ++N+ N + + ++I LNQK+ + Q + Sbjct: 1074 EIAKYQ-QQIDE-LNEEKSNSEKQINELNQKLNQNNEEINKYQKQIEDLNQKLKDLQENN 1131 Query: 1040 MSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETK 1099 ++ Y++++ K + EE+ K++ + K+ + + E ++ + E K+++ Sbjct: 1132 QE-IAKYQNEVDDLKKKFDVSNEEIANKEKEIEEMKKKEQNYLKQISELNNHLME-KQSE 1189 Query: 1100 LTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQE 1159 + +N K + I + + + + N D K+++ E QE + L + Sbjct: 1190 IV-NLN-SKLDNQIYNLNTKKQNLEMNLNDLQT----------KLKQIE---QENANLSK 1234 Query: 1160 QSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAE 1219 ++ L E Q ++ + N +LT +++ +L +L ++ N N S + + Sbjct: 1235 RNKDLENESQNQAKITLETQNKNVDLTNKVKSLEQESQKLIQQLSEITKLNANYSSELED 1294 Query: 1220 LRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSST 1279 LR +SS L + + + + E LR ++ ++ + L + +Q Sbjct: 1295 LREKVSSLTTS---------NNELTKSKQESTELEEHLRKAVNDLTNENQSLTNGLQ--- 1342 Query: 1280 QEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEI--EDEKVA--FX 1335 ET ++V ++ T + Q N Q K I Q ++ +SEI DE+V Sbjct: 1343 --ETERLVAEQRKTMKEQHDQFTALEKENQQLKSEKTILQKQLEKSEIAHHDEEVVKEKE 1400 Query: 1336 XXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQL-KKSSXXXXXXXXXXXXR 1394 + Q +Q+Q ++++N + + S R Sbjct: 1401 ETIQGLKKLLQRYVNTTKRNQQQIDDLQQQVTTLLSQQNTSVGTEDSNKYLETVHRQEER 1460 Query: 1395 VNDAEAKV--LELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQL-VEYEKRIEDL 1451 + + E ++ + T +E K ++ + + + T+ E E++ +QL E EKR Sbjct: 1461 IKELEERLESSQATKDIENKAQKMAKMLEKSSRQYTELLSEKEDILKQLNQEKEKRFAKF 1520 Query: 1452 TYEKESELAILRLKMHENANHYETMQKESEIERVKLI 1488 K+ + L E + E+E E++K++ Sbjct: 1521 EVSKDVFFEMAELTPEEEERRRKEELSEAENEKIKVM 1557 Score = 171 bits (416), Expect = 1e-40 Identities = 259/1330 (19%), Positives = 575/1330 (43%), Gaps = 128/1330 (9%) Query: 323 ELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKM 382 ++ +K E+++ L+ +I+ + +L T +E +A + K+ +K+ + +++ Sbjct: 136 QIAEKEEIIQALSQKIQTYSDQLA--ATTTPSEFEAKYNAEKEAFSKF-KKAAKAAIAQV 192 Query: 383 KSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXX 442 ++ +L ++ N TD + K + E +Q + K+L + + ++T Sbjct: 193 QTENEELKAKLANASTDNEYTKQLEQQREEALQKV-KELTSRNLELEAQETDFISKLEEL 251 Query: 443 XGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVN-VKDL 501 DT + QL+ ++ +LI N + E K ++L ++ + V +++ Sbjct: 252 ---DTELQQLRSNQNNNIS--NLIQSQNNQYSLKEDNKDSQELSSQIQNLNSMVQKLQNE 306 Query: 502 IEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLT 561 + + K EQ + DE++A N ++I KS + +L + ++ + S + + + Sbjct: 307 LSESKLLNEQNSSKIDELNALNNSLIDEKSRLESELSNAKAKVEQSNTNSSA---MAQNN 363 Query: 562 EELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYK--KMIEMENLAETRLKAISLL 619 +L L++ + +L EK L+ L IE D K ++ + N + + Sbjct: 364 AKLQELNEMIQKLTNEKNQLEKDLKS-----QIEQDKAKLNELSQQNNKISEEKSQLQKI 418 Query: 620 ESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELA 679 Q +QEL+ QK E K+ D++ L + ++ ++ + +++ + S+ ++L Sbjct: 419 YEQNNTKMQELN---QKLANSEAKINDLNAL-NQKISGDLNNSKSQKEKE--SSKLQQL- 471 Query: 680 LVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKI 739 N L +E+ + ++ L K +QN ++EN +++L K S + AKI Sbjct: 472 ----NQNLSEEKAF-ILQQLNETKIS----MQNLMEENDHFSNEL-KQSKSLNDQNNAKI 521 Query: 740 NHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKA 799 K Q Q I +E+ ++ S+L+ + + + + + + LE + Sbjct: 522 KELSDQKSQLQTNISKLEKEKS----DLISKLNDVNKLVEQSSQKLQSNNNEKLQLENEL 577 Query: 800 DQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHEN---KELQKKNQ 856 S +++ E + ++ N+L + + + ++ ++ EN +E+++K++ Sbjct: 578 KASKSLIEQSNIKEQELNQKISQIQNQLNNSNAKIQELSENIMNLKSENAKLREMKQKSE 637 Query: 857 ILLEENQNLQISLSDMQQHYNALVEKAN-RTDLAESESTKYQTQLRDLESNLKRITHEHQ 915 E N NLQ + +M + L++ N + D ++S + Q+ +L++ + ++ +E Sbjct: 638 ENSENNINLQ-KIEEMNREKEELIKSYNDKIDNMTNDSIQLVNQISELKNTISKLQNEKI 696 Query: 916 TLIVQKKKEIEDLEIEFNTQIESAIRD--KK--VLNEKYEKNIEYVTQLEAQLQEYKNNI 971 + + K+E+ + + N IE ++ KK ++NE+ + NI + QL QLQE N Sbjct: 697 EIQNRMKREVSAVTEQKNESIERLQQEILKKDGIINEQ-KSNISELEQLALQLQEENNTF 755 Query: 972 ----ENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNA-------LLKQ 1020 E + EE KM + + + + + T+ +N L A LL+ Sbjct: 756 LDSKEEFDKLKEEYEKMKQDSNNPKINELEQNVKQLTKALQKTLNDLKAAKSENEQLLQS 815 Query: 1021 K--DEEIIALNQKI-------NNAQVSYMSMVSD-------YESKLAQFTTKLENMEEEM 1064 D++II+LN+KI N+ + + ++ S+ YE ++ Q + +L + Sbjct: 816 NNSDQKIISLNKKIDSLNQSINDYEETTKALASENYEITQKYEQQINQISNQLNEKNVLL 875 Query: 1065 QRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMN----IPKTEGMIISSTIEP 1120 Q KQ+ D +Q N+EL + E Q KE KE + ++N I + + ++ Sbjct: 876 QEKEKQINDLEQENKELNNQLNEMQ-QDKEEKEERYQQQINDLQKISNEQQNVQIIELQT 934 Query: 1121 MSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKII---- 1176 + + NN ++ + + +S E L +LQ+ +I Sbjct: 935 ENKELNNQLNEMQQIKEKSEAEYQKQINDLLSNKSNNSEMIESLRRKLQQNEEEITNYKK 994 Query: 1177 QLETLN-TELTGHDVVN-QEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFE 1234 Q+ LN T+ +++N Q+QIN+LK +L ND +A + I Q E Sbjct: 995 QINELNNTKQNNEEIINYQKQINELKKELNITKQNND----LIANYKKQIEELSKQSNEE 1050 Query: 1235 IAELWKQ--HLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQV 1292 + KQ L + D Q+ E+ +KY+Q +D + +E++N + +Q+ Sbjct: 1051 VVNYQKQVEDLKNKLIDLQQNNQEI--------AKYQQQIDELN---EEKSN---SEKQI 1096 Query: 1293 TSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDL 1352 L KL E + Q++ D+ +++ L+ ++++A DL Sbjct: 1097 NELNQKLNQNNEEINKYQKQIEDLNQKLKDLQEN--NQEIA----------KYQNEVDDL 1144 Query: 1353 RTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELK 1412 + + + + I N +E ++KK + + +++++ L +L+ + Sbjct: 1145 KKKFD----VSNEEIANKEKEIEEMKKKEQNYLKQISELNNHLMEKQSEIVNLNSKLDNQ 1200 Query: 1413 DSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANH 1472 + K + L + + + Q+ KR +DL E +++ I ++N + Sbjct: 1201 IYNLNTKKQNLEMNLNDLQTKLKQIEQENANLSKRNKDLENESQNQAKITLETQNKNVDL 1260 Query: 1473 YETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEM-QTALENQEI 1531 + K E E KLI++L+ + + + ++ +L + + NE+ ++ E+ E+ Sbjct: 1261 TNKV-KSLEQESQKLIQQLSEITKLNANYSSELEDLREKVSSLTTSNNELTKSKQESTEL 1319 Query: 1532 EIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDL 1591 E L + +L N ++ ++ +Q+ ++ ++ EQ D E + ++E + Sbjct: 1320 E-EHLRKAVNDLTNENQSLTNGLQETERLVAEQRKTMKEQHDQFTALEKENQQLKSEKTI 1378 Query: 1592 AMYMLHQRDV 1601 L + ++ Sbjct: 1379 LQKQLEKSEI 1388 Score = 171 bits (416), Expect = 1e-40 Identities = 254/1283 (19%), Positives = 562/1283 (43%), Gaps = 96/1283 (7%) Query: 337 QIRQTNKELENKLATMGTE---SKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSET 393 Q++ N+EL+ KLA T+ +K + ++ + + RN ++++ + S+ Sbjct: 191 QVQTENEELKAKLANASTDNEYTKQLEQQREEALQKVKELTSRNL--ELEAQETDFISKL 248 Query: 394 LNQDTD-KKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQL 452 DT+ +++ N+ + +IQS N +Y + E + ++++ +L Sbjct: 249 EELDTELQQLRSNQNNNISNLIQSQN-----NQYSLKEDNKDSQELSSQIQNLNSMVQKL 303 Query: 453 QLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQL---KQELNDEIKDVNVKDLIEKLKSAE 509 Q E + S + N+ ++E+ + L K L E+ N K +E+ + Sbjct: 304 QNELSE-----SKLLNEQNSSKIDELNALNNSLIDEKSRLESELS--NAKAKVEQSNTNS 356 Query: 510 EQITQLNDEIDAANKNMIKVKSNHKLKL-KQMQKTID-NFSKVSDSNKEIVRLTEELHHL 567 + Q N ++ N+ MI+ +N K +L K ++ I+ + +K+++ +++ +++EE L Sbjct: 357 SAMAQNNAKLQELNE-MIQKLTNEKNQLEKDLKSQIEQDKAKLNELSQQNNKISEEKSQL 415 Query: 568 SQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMI--EMENLAETRLKAISLLESQKFD 625 QK+ E K + ++ + + + I ++ N + K S L+ + Sbjct: 416 -QKIYEQNNTKMQELNQKLANSEAKINDLNALNQKISGDLNNSKSQKEKESSKLQQLNQN 474 Query: 626 LVQELHILQQKYDEVEDKLADISQLQSDQVCSEIK-SVHLEEQ----IDALSASKKELAL 680 L +E + Q+ +E + + ++ + ++D +E+K S L +Q I LS K +L Sbjct: 475 LSEEKAFILQQLNETKISMQNLME-ENDHFSNELKQSKSLNDQNNAKIKELSDQKSQLQT 533 Query: 681 VIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLE-KMSAEKISELLAKI 739 I L+ +K L + D+ E KLQ+ E + L ++L+ S + S + + Sbjct: 534 NISKLEKEKSDLISKLNDVNKLVEQSSQKLQSNNNEKLQLENELKASKSLIEQSNIKEQE 593 Query: 740 NHEEQSKIQTQF-GIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERK 798 +++ S+IQ Q +AKIQE I N++SE +K + + EE+ + +L+ K Sbjct: 594 LNQKISQIQNQLNNSNAKIQELSENIMNLKSENAKLREMKQKSEEN----SENNINLQ-K 648 Query: 799 ADQLGSYLQEKQKAYSE----YTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKK 854 +++ +E K+Y++ T +LVN+++ L + ++ + +EI +N+ ++ Sbjct: 649 IEEMNREKEELIKSYNDKIDNMTNDSIQLVNQISELKNTISKLQNEKIEI--QNRMKREV 706 Query: 855 NQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQ-----LRDLESNLKR 909 + + ++N++++ ++ + + E+ +++++E E Q Q D + + Sbjct: 707 SAVTEQKNESIERLQQEILKKDGIINEQ--KSNISELEQLALQLQEENNTFLDSKEEFDK 764 Query: 910 ITHEHQTLIVQ----KKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQ 965 + E++ + K E+E + ++ + D K + E+ ++ + ++ Sbjct: 765 LKEEYEKMKQDSNNPKINELEQNVKQLTKALQKTLNDLKAAKSENEQLLQ-SNNSDQKII 823 Query: 966 EYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEI 1025 I++LN ++ + + L ++ + Q + Q N++N+ N LL++K+++I Sbjct: 824 SLNKKIDSLNQSINDYEETTKALASENYEITQ-KYEQQINQISNQLNEKNVLLQEKEKQI 882 Query: 1026 IAL---NQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQ 1082 L N+++NN + E + Q L+ + E Q V Q+++ + N+EL Sbjct: 883 NDLEQENKELNNQLNEMQQDKEEKEERYQQQINDLQKISNEQQNV--QIIELQTENKELN 940 Query: 1083 ILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSD--DANNVDXXXXXXXXXXX 1140 + E QIKE E + ++N + S IE + N + Sbjct: 941 NQLNEM-QQIKEKSEAEYQKQINDLLSNKSNNSEMIESLRRKLQQNEEEITNYKKQINEL 999 Query: 1141 XLKVQEEEEFIQERSVLQEQSAKL-----NTELQECYTKIIQLETLNTELTGHDVVN-QE 1194 Q EE I + + E +L N +L Y K Q+E L+ + + +VVN Q+ Sbjct: 1000 NNTKQNNEEIINYQKQINELKKELNITKQNNDLIANYKK--QIEELSKQ-SNEEVVNYQK 1056 Query: 1195 QINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTE 1254 Q+ LK+KL L N + ++ ++ +I EL Q L Q + K + Sbjct: 1057 QVEDLKNKLIDLQQNNQEIAKYQQQI-DELNEEKSNSEKQINEL-NQKLNQNNEEINKYQ 1114 Query: 1255 HELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQN-KLQDKEEHLRNLQEKY 1313 Q+ K + L ++ Q + + N++ +++ + N ++ +KE+ + +++K Sbjct: 1115 K----QIEDLNQKLKDLQENNQEIAKYQ-NEVDDLKKKFDVSNEEIANKEKEIEEMKKKE 1169 Query: 1314 ADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEE 1373 + + QI L + + +++ + + +Q + + I +E Sbjct: 1170 QNYLKQISELNNHLMEKQSEIVNLNSKLDNQIYNLNTKKQNLEMNLNDLQTK-LKQIEQE 1228 Query: 1374 NAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQ---LELKDSEIYQKTHEYTITLTQR 1430 NA L K + + + K ++LT++ LE + ++ Q+ E T Sbjct: 1229 NANLSKRNKDLENESQNQAKITLETQNKNVDLTNKVKSLEQESQKLIQQLSEITKLNANY 1288 Query: 1431 NDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEE 1490 + E E++R+++ +LT K+ E L + + N T + +S ++ E Sbjct: 1289 SSELEDLREKVSSLTTSNNELTKSKQ-ESTELEEHLRKAVNDL-TNENQSLTNGLQETER 1346 Query: 1491 LNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQ--EIEIVTLNDEIT-NLQNMV 1547 L + E K+ + ALE+E + +T L+ Q + EI ++E+ + + Sbjct: 1347 L---VAEQRKTMKEQHDQFTALEKENQQLKSEKTILQKQLEKSEIAHHDEEVVKEKEETI 1403 Query: 1548 RASSSKIQKHVSFASDTKQGRDE 1570 + +Q++V+ +Q D+ Sbjct: 1404 QGLKKLLQRYVNTTKRNQQQIDD 1426 Score = 164 bits (399), Expect = 2e-38 Identities = 236/1136 (20%), Positives = 497/1136 (43%), Gaps = 100/1136 (8%) Query: 502 IEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLT 561 +E LK + QI + +EI A I+ S+ Q+ T + N E + Sbjct: 127 LEALKEKDRQIAE-KEEIIQALSQKIQTYSD------QLAATTTPSEFEAKYNAEKEAFS 179 Query: 562 EELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLES 621 + +A+++ E L+ L + + + Y K +E + E L+ + L S Sbjct: 180 KFKKAAKAAIAQVQTENEELKAKLANAST-----DNEYTKQLEQQR--EEALQKVKELTS 232 Query: 622 QKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALV 681 + +L + K +E++ +L + Q++ + + I+S + + + + +EL+ Sbjct: 233 RNLELEAQETDFISKLEELDTELQQLRSNQNNNISNLIQSQNNQYSLKEDNKDSQELSSQ 292 Query: 682 IENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINH 741 I+NL ++L + + + E +K+ N L D+ ++ +E +S AK+ Sbjct: 293 IQNLNSMVQKLQNELSESKLLNEQNSSKIDELNALNNSLIDEKSRLESE-LSNAKAKVEQ 351 Query: 742 ---------EEQSKIQTQFGIDAKI-QERDLYIENIESELSKYKSRICRLEESIAVMEDR 791 + +K+Q + K+ E++ ++++S++ + K+++ L + + + Sbjct: 352 SNTNSSAMAQNNAKLQELNEMIQKLTNEKNQLEKDLKSQIEQDKAKLNELSQQNNKISEE 411 Query: 792 RYSLERKADQLGSYLQE-KQK-AYSEYTIQEDELVNRLAV--LMDHDRVVEKQLLEIEHE 847 + L++ +Q + +QE QK A SE I + +N+ L + EK+ +++ Sbjct: 412 KSQLQKIYEQNNTKMQELNQKLANSEAKINDLNALNQKISGDLNNSKSQKEKESSKLQQL 471 Query: 848 NKELQKKNQILLEENQNLQISLSDMQQ---HY-NALVEKANRTDLAESESTKYQTQLRDL 903 N+ L ++ +L++ +IS+ ++ + H+ N L + + D ++ + Q L Sbjct: 472 NQNLSEEKAFILQQLNETKISMQNLMEENDHFSNELKQSKSLNDQNNAKIKELSDQKSQL 531 Query: 904 ESNLKRITHEHQTLI-----VQKKKEIEDLEIEFNT----QIESAIRDKKVLNEKYEKNI 954 ++N+ ++ E LI V K E +++ N Q+E+ ++ K L E + NI Sbjct: 532 QTNISKLEKEKSDLISKLNDVNKLVEQSSQKLQSNNNEKLQLENELKASKSLIE--QSNI 589 Query: 955 EYVTQLEAQLQEYKNNIENLNMNVEEL--NKMNLELIDKHVQKQQTQSPDYTEQYINEIN 1012 + +L ++ + +N + N N ++EL N MNL+ + +++ + +S + +E IN + Sbjct: 590 KE-QELNQKISQIQNQLNNSNAKIQELSENIMNLKSENAKLREMKQKSEENSENNIN-LQ 647 Query: 1013 KLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLL 1072 K+ + ++K+E I + N KI+N + +V+ S+L +KL+N + E+Q K+ + Sbjct: 648 KIEEMNREKEELIKSYNDKIDNMTNDSIQLVNQI-SELKNTISKLQNEKIEIQNRMKREV 706 Query: 1073 DS--KQHNEELQIL----------VREQDDQIKELKETKLTF--EMNI---PKTEGMIIS 1115 + +Q NE ++ L + EQ I EL++ L E N K E + Sbjct: 707 SAVTEQKNESIERLQQEILKKDGIINEQKSNISELEQLALQLQEENNTFLDSKEEFDKLK 766 Query: 1116 STIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKI 1175 E M D+NN +Q+ ++ EQ + N Q KI Sbjct: 767 EEYEKMKQDSNNPKINELEQNVKQLTKALQKTLNDLKAAKSENEQLLQSNNSDQ----KI 822 Query: 1176 IQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEI 1235 I +LN ++ D +NQ IN + + L +EN + + + IS+ ++++ + Sbjct: 823 I---SLNKKI---DSLNQS-INDYEETTKALASENYEITQKYEQQINQISNQLNEKNVLL 875 Query: 1236 AELWKQ--HLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETN-KIVTME-Q 1291 E KQ L Q + +E++ E +Y+Q ++ +Q + E+ N +I+ ++ + Sbjct: 876 QEKEKQINDLEQENKELNNQLNEMQQDKEEKEERYQQQINDLQKISNEQQNVQIIELQTE 935 Query: 1292 VTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXD 1351 L N+L + ++ + +Y IN + +S E + Sbjct: 936 NKELNNQLNEMQQIKEKSEAEYQKQINDLLSNKSN-NSEMIESLRRKLQQNEEEITNYKK 994 Query: 1352 LRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLEL 1411 E + KQ E+ I+N ++ +LKK + ND A + +L Sbjct: 995 QINELNNTKQNNEE-IINYQKQINELKKE--------LNITKQNNDLIANYKKQIEELSK 1045 Query: 1412 KDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKE-SELAILRLKMHENA 1470 + +E + L + + + Q++ +Y+++I++L EK SE I L N Sbjct: 1046 QSNEEVVNYQKQVEDLKNKLIDLQQNNQEIAKYQQQIDELNEEKSNSEKQINELNQKLNQ 1105 Query: 1471 NHYETMQKESEIERV-KLIEELNVKITESVSLNKQVAELNKALE---EEVA----KTNEM 1522 N+ E + + +IE + + +++L E +V +L K + EE+A + EM Sbjct: 1106 NNEEINKYQKQIEDLNQKLKDLQENNQEIAKYQNEVDDLKKKFDVSNEEIANKEKEIEEM 1165 Query: 1523 QTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNK 1578 + +N +I LN+ + Q+ + +SK+ + + KQ + L++ K Sbjct: 1166 KKKEQNYLKQISELNNHLMEKQSEIVNLNSKLDNQIYNLNTKKQNLEMNLNDLQTK 1221 Score = 118 bits (285), Expect = 1e-24 Identities = 202/1089 (18%), Positives = 455/1089 (41%), Gaps = 53/1089 (4%) Query: 142 GDVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKD---QIIEAKNKATTXXXX 198 GD+ + S + KEK+++ + Q+ + E LQ+ +NE Q + +N + Sbjct: 452 GDLNN-SKSQKEKESS-KLQQLNQNLSEEKAFILQQ-LNETKISMQNLMEENDHFSNELK 508 Query: 199 XXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANK 258 ++ Q +++Q N +E E D +L D+ +K V SS + + Sbjct: 509 QSKSLNDQNNAKIKELSDQKSQLQTNISKLEKEKSDLISKL-NDV-NKLVEQSSQKLQSN 566 Query: 259 LLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEI 318 E + E L+ SK E + +E +E E Sbjct: 567 NNEKLQLENELKASKSLIEQSNIKEQELNQKISQIQNQLNNSNAKIQELSENIMNLKSEN 626 Query: 319 ANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSG-RN 377 A + E+ +K E N +++ + K + + + + + + L+++ S +N Sbjct: 627 AKLREMKQKSEENSENNINLQKIEEMNREKEELIKSYNDKIDNMTNDSIQLVNQISELKN 686 Query: 378 TASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXX 437 T SK+++ ++ + + + KNE I+ L ++++ K+ +I+E+ + Sbjct: 687 TISKLQNEKIEIQNRMKREVSAVTEQKNES------IERLQQEILKKDGIINEQKSNISE 740 Query: 438 XXXXXXG---KDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIK 494 ++ + E + E + +N +NE+ + +QL + L + Sbjct: 741 LEQLALQLQEENNTFLDSKEEFDKLKEEYEKMKQDSNNPKINELEQNVKQLTKALQKTLN 800 Query: 495 DVNV-KDLIEKL---KSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSK- 549 D+ K E+L +++++I LN +ID+ N+++ + K + + + + Sbjct: 801 DLKAAKSENEQLLQSNNSDQKIISLNKKIDSLNQSINDYEETTKALASENYEITQKYEQQ 860 Query: 550 VSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLA 609 ++ + ++ L +++ +LE+E L L + + + + Y++ I Sbjct: 861 INQISNQLNEKNVLLQEKEKQINDLEQENKELNNQLNEMQQDKEEKEERYQQQINDLQKI 920 Query: 610 ETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQID 669 + + ++E Q + +EL+ + ++++K Q Q + + S KS + E I+ Sbjct: 921 SNEQQNVQIIELQTEN--KELNNQLNEMQQIKEKSEAEYQKQINDLLSN-KSNN-SEMIE 976 Query: 670 ALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMN--KLQNYIQENMDLTDKLEKM 727 +L ++ I N K +L T + + E+I+N K N +++ +++T + + Sbjct: 977 SLRRKLQQNEEEITNYKKQINELNNT----KQNNEEIINYQKQINELKKELNITKQNNDL 1032 Query: 728 SA--EKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESI 785 A +K E L+K ++EE Q Q D K + DL N E++KY+ +I L E Sbjct: 1033 IANYKKQIEELSKQSNEEVVNYQKQVE-DLKNKLIDLQQNN--QEIAKYQQQIDELNEEK 1089 Query: 786 AVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIE 845 + E + L +K +Q + + QK + + +L + + V+ + + Sbjct: 1090 SNSEKQINELNQKLNQNNEEINKYQKQIEDLNQKLKDLQENNQEIAKYQNEVDDLKKKFD 1149 Query: 846 HENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLES 905 N+E+ K + + E + Q L + + N L+EK + S+ L + Sbjct: 1150 VSNEEIANKEKEIEEMKKKEQNYLKQISELNNHLMEKQSEIVNLNSKLDNQIYNLNTKKQ 1209 Query: 906 NLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDK-KVLNEKYEKNIEYVTQLEAQL 964 NL+ ++ QT + Q ++E +L + N +E+ +++ K+ E KN++ ++++ Sbjct: 1210 NLEMNLNDLQTKLKQIEQENANLS-KRNKDLENESQNQAKITLETQNKNVDLTNKVKSLE 1268 Query: 965 QEYKNNIENLNMNVEELN---KMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQK 1021 QE + I+ L+ + +LN LE + + V T + + T+ E +L L++ Sbjct: 1269 QESQKLIQQLS-EITKLNANYSSELEDLREKVSSLTTSNNELTKSK-QESTELEEHLRKA 1326 Query: 1022 DEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRV--SKQLLDSKQHNE 1079 ++ NQ + N +V++ + + + +E+E Q++ K +L + Sbjct: 1327 VNDLTNENQSLTNGLQETERLVAEQRKTMKEQHDQFTALEKENQQLKSEKTILQKQLEKS 1386 Query: 1080 EL----QILVREQDDQIKELKETKLTFEMNIPKTEGMI--ISSTIEPMSDDANNVDXXXX 1133 E+ + +V+E+++ I+ LK+ + + + I + + + N Sbjct: 1387 EIAHHDEEVVKEKEETIQGLKKLLQRYVNTTKRNQQQIDDLQQQVTTLLSQQNTSVGTED 1446 Query: 1134 XXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQ 1193 + +E + ++ER + + + + Q+ + + TEL Sbjct: 1447 SNKYLETVHRQEERIKELEERLESSQATKDIENKAQKMAKMLEKSSRQYTELLSEKEDIL 1506 Query: 1194 EQINQLKSK 1202 +Q+NQ K K Sbjct: 1507 KQLNQEKEK 1515 Score = 109 bits (262), Expect = 6e-22 Identities = 145/725 (20%), Positives = 301/725 (41%), Gaps = 55/725 (7%) Query: 891 SESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFN------TQIESAIRDKK 944 +E + +QL L+ L +EH LI ++K +I ++E+E + + +R+ Sbjct: 25 TELQRICSQLFTLKEKLNNTKNEHLALIERQKNQISEMELEIQCSKSQLSSFQDLVRESV 84 Query: 945 VLNEKYEKNIEYVTQLEAQLQEYKNN------------IENLNMNVEELNKMNLELIDKH 992 EKY+K +LEAQ+ ++K+N ++ N N+E L + + ++ +K Sbjct: 85 DEKEKYQKK---CAELEAQIADFKSNNLQSDPLNITTPSQDSNSNLEALKEKDRQIAEKE 141 Query: 993 --VQKQQTQSPDYTEQYINEINKLNALLK-QKDEEIIALNQKINNAQVSYMSMVS-DYES 1048 +Q + Y++Q K ++E + +K A ++ + + + ++ Sbjct: 142 EIIQALSQKIQTYSDQLAATTTPSEFEAKYNAEKEAFSKFKKAAKAAIAQVQTENEELKA 201 Query: 1049 KLAQFTTKLE---NMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMN 1105 KLA +T E +E++ + +++ + N EL+ + +++EL N Sbjct: 202 KLANASTDNEYTKQLEQQREEALQKVKELTSRNLELEAQETDFISKLEELDTELQQLRSN 261 Query: 1106 IPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLN 1165 +I S S +N D VQ+ + + E +L EQ++ Sbjct: 262 QNNNISNLIQSQNNQYSLKEDNKDSQELSSQIQNLNSMVQKLQNELSESKLLNEQNSSKI 321 Query: 1166 TELQECYTKII-QLETLNTELTGHDV-VNQEQIN-----QLKSKLEQLNTENDNLLSTVA 1218 EL +I + L +EL+ V Q N Q +KL++LN L + Sbjct: 322 DELNALNNSLIDEKSRLESELSNAKAKVEQSNTNSSAMAQNNAKLQELNEMIQKLTNEKN 381 Query: 1219 ELRSSISSAVDQRGFEIAELWKQH--LAQREADFQKTEHELRVQLSAFESKY---EQLLD 1273 +L + S ++Q ++ EL +Q+ +++ ++ QK + ++ K E ++ Sbjct: 382 QLEKDLKSQIEQDKAKLNELSQQNNKISEEKSQLQKIYEQNNTKMQELNQKLANSEAKIN 441 Query: 1274 SVQSSTQEETNKI-VTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKV 1332 + + Q+ + + + Q +KLQ ++L + +N+ +I + +E Sbjct: 442 DLNALNQKISGDLNNSKSQKEKESSKLQQLNQNLSEEKAFILQQLNETKISMQNLMEEND 501 Query: 1333 AFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXX 1392 F ++ + Q+Q +I + +E + L Sbjct: 502 HFSNELKQSKSLNDQNNAKIKELSDQKSQLQ-TNISKLEKEKSDLISKLNDVNKLVEQSS 560 Query: 1393 XRVNDAEAKVLELTHQLELKDSEIYQ---KTHEYTITLTQRNDEFENVRQQLVEYEKRIE 1449 ++ + L+L ++L+ S I Q K E ++Q ++ N ++ E + I Sbjct: 561 QKLQSNNNEKLQLENELKASKSLIEQSNIKEQELNQKISQIQNQLNNSNAKIQELSENIM 620 Query: 1450 DLTYEKESELAILRLKMHENANHYETMQKESEIERVK--LIEELNVKI----TESVSLNK 1503 +L E ++L ++ K EN+ + +QK E+ R K LI+ N KI +S+ L Sbjct: 621 NLKSE-NAKLREMKQKSEENSENNINLQKIEEMNREKEELIKSYNDKIDNMTNDSIQLVN 679 Query: 1504 QVAELNKALEEEVAKTNEMQTALENQEIEIVT--LNDEITNLQNMVRASSSKIQKHVSFA 1561 Q++EL + + + E+Q ++ +E+ VT N+ I LQ + I + S Sbjct: 680 QISELKNTISKLQNEKIEIQNRMK-REVSAVTEQKNESIERLQQEILKKDGIINEQKSNI 738 Query: 1562 SDTKQ 1566 S+ +Q Sbjct: 739 SELEQ 743 Score = 58.8 bits (136), Expect = 1e-06 Identities = 86/435 (19%), Positives = 186/435 (42%), Gaps = 35/435 (8%) Query: 1149 EFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNT 1208 E + E+ Q++ A+L ++ + + +Q + LN D + + LK K Q+ Sbjct: 82 ESVDEKEKYQKKCAELEAQIADFKSNNLQSDPLNITTPSQD--SNSNLEALKEKDRQI-A 138 Query: 1209 ENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKY 1268 E + ++ +++ + S + +E ++ A++EA F K + + ++ +++ Sbjct: 139 EKEEIIQALSQKIQTYSDQLAATTTP-SEFEAKYNAEKEA-FSKFKKAAKAAIAQVQTEN 196 Query: 1269 EQLLDSV-QSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEI 1327 E+L + +ST E K + ++ +LQ K+++ L+ + D I+++E L +E+ Sbjct: 197 EELKAKLANASTDNEYTKQLEQQREEALQ-KVKELTSRNLELEAQETDFISKLEELDTEL 255 Query: 1328 EDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXX 1387 + + + L+ +N+ +++ Q I N+N +L+ Sbjct: 256 QQLR-SNQNNNISNLIQSQNNQYSLKEDNKDSQELSSQ-IQNLNSMVQKLQNELSESKLL 313 Query: 1388 XXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKR 1447 ++++ A L + +SE+ + + T + +N +L E + Sbjct: 314 NEQNSSKIDELNALNNSLIDEKSRLESELSNAKAKVEQSNTNSSAMAQN-NAKLQELNEM 372 Query: 1448 IEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAE 1507 I+ LT EK N E K S+IE+ K +LN ++ ++++ ++ Sbjct: 373 IQKLTNEK---------------NQLEKDLK-SQIEQDKA--KLNELSQQNNKISEEKSQ 414 Query: 1508 LNKALEEEVAKTNEMQTALENQEIEIVTLN-------DEITNLQNMVRASSSKIQKHVSF 1560 L K E+ K E+ L N E +I LN ++ N ++ SSK+Q+ Sbjct: 415 LQKIYEQNNTKMQELNQKLANSEAKINDLNALNQKISGDLNNSKSQKEKESSKLQQLNQN 474 Query: 1561 ASDTKQGRDEQLDNT 1575 S+ K +QL+ T Sbjct: 475 LSEEKAFILQQLNET 489 >UniRef50_A2ETW9 Cluster: Viral A-type inclusion protein, putative; n=1; Trichomonas vaginalis G3|Rep: Viral A-type inclusion protein, putative - Trichomonas vaginalis G3 Length = 2010 Score = 177 bits (431), Expect = 2e-42 Identities = 297/1410 (21%), Positives = 613/1410 (43%), Gaps = 125/1410 (8%) Query: 215 KQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKL 274 KQQ+ K+Q + + + RL K E IS+L+ N L+ ++SL SK+ Sbjct: 236 KQQLIKLQNDLDEERVKSVATEDRLTKFREESSKAISTLKSQNSNLQE---QLSL--SKI 290 Query: 275 AQELEQXXXXXXXXXXXXXXLAKQS-IEPSCEEKTEIEEKGSLEIANMTELTKK----IE 329 Q Q K + I+ +E + EE+ + A +TEL K I+ Sbjct: 291 EQNSAQNAGNDELLKIKSEIDDKNNEIKNLQQEISNFEEENANLNAKITELEKSAKKSIQ 350 Query: 330 LLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQL 389 + L +I ++ELE + T TES S +K + N +++ +QL Sbjct: 351 TISILEKEIDDLSEELEKQQVTK-TESN--SDDFQKQVEAVRLVKEEN--DQLRDQINQL 405 Query: 390 SSETLNQDTDKKINKNEIAKLEMVIQSLNKDLV--DKEYVISEKDTXXXXXXXXXXGKDT 447 + + + + +N+ K E + L+ + E ++ E + + Sbjct: 406 T--VYKEKMNSILKENQNLKSEYIKMKDENTLLREENERIMEESNAAKENLKKENENQKN 463 Query: 448 LIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDL-IEKLK 506 I+ L E + L + + + + + Q ++ Q+LN+E+ + K+ +KL Sbjct: 464 EISSLTNEDE-------LYKLREENDKLIKSREAQNEIIQKLNNEMNQMKEKEKDFDKLA 516 Query: 507 SAEEQITQLNDE-IDAANKNMIKVKSNHKLKLKQMQKTI----DNFSKVSDSNKEIVRLT 561 ++ + ND I++ + + K K ++ ++Q+ +N +K ++ + +L Sbjct: 517 QEKKLLKDENDRLINSEMEELDKYKKENQDLNNELQRIKNERQENENKENNLKQGNEQLN 576 Query: 562 EELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLES 621 EEL Q V EEE ++ + D R ++ +K N E K I E Sbjct: 577 EELQRTKQTVINKEEELKKVR---DEADKLRKKIEELKEKQQNQINDNEELRKEIKSSEE 633 Query: 622 QKFDLVQELHILQQKYDEVEDKLADISQ-LQSDQVCSEIK-SVHLEEQIDALSASKKELA 679 + ++ E IL+++ ++ ++ ++IS LQ S +K S+ ++ + KKE Sbjct: 634 KMKEIQSENEILKKQIEKEDENSSNISDDLQKLVNKSLVKESIDENNDVETIENLKKE-- 691 Query: 680 LVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQ---ENMDLTDKLEKMSAE--KISE 734 IE+LK +K+ + +I +EN ED+ ++++ I+ E ++++LEK+ A ++ Sbjct: 692 --IEDLKKEKDN-FDSIS-IEN--EDLRSQVEVLIKVEDERNQMSEELEKLRANYNELQS 745 Query: 735 LLAKINHEEQSK-IQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRY 793 ++K N E + I+ G +K+QE +E+I++EL + E + + Sbjct: 746 QISKQNFENNKETIEKLIGEKSKLQEE---LESIKNELDSIQVEKIESENESS---SKII 799 Query: 794 SLERKADQLGSYLQE--KQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKEL 851 +L + D+L + + +QK+ E+TI E + N E ++ +++ EN++L Sbjct: 800 ALTEEIDELKNQINNISEQKSTLEFTIDEIKAQN------------ESEISQLKKENEDL 847 Query: 852 QKKNQILLEENQNLQISLSDMQQ-HYNALVEKANRTDLAESESTKYQTQLRDLESNLKRI 910 K + L +EN L+ + ++Q H +L+E L + + L++ N+KR Sbjct: 848 NSKIESLSKENNELKTEIENIQNSHSLSLLETEMNNKL--TNLNEENDMLKNENENIKR- 904 Query: 911 THEHQTLIVQKK-KEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKN 969 + +TL K K+ D + T+I +DK E+ +K V L + E K+ Sbjct: 905 -EKEETLAENKSLKDTLDFFEKNLTKINEQNKDK---TEELDKQKRIVLTLTGENNELKS 960 Query: 970 NIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALN 1029 ++ + + E L K N +L Q + + + + N LK++ E++ A N Sbjct: 961 KLDKIKNDYELLQKENEKLESDIDNPQNLSLLEEMNSKLTALTEENKKLKEEIEDLQAEN 1020 Query: 1030 QKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNE---ELQILVR 1086 + + N S + ++ SKL T + +++E +++ L ++ E +L L Sbjct: 1021 EALQNTH-SLSLLETEMNSKLTSLTEENGKLKKENEKLKIDLQNNSIEKELKLKLTKLTE 1079 Query: 1087 EQDDQIKELKETK-LTFEMNIPKTEGMI---ISSTIEPMSDDANNVDXXXXXXXXXXXXL 1142 E + KE KE K + +MN + ++ +++ + +S++ N + Sbjct: 1080 ENEKLGKESKELKQIIDQMNDTHSLSLLETEMNNKLASLSEENNKLKEENNKLTKSNEKA 1139 Query: 1143 KVQEE------EEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTEL----------T 1186 K + + +E+ + ++++ L+ E Q ++KI L N E+ + Sbjct: 1140 KTEYQSLKTIVDEYGNDYEEMKQKIEDLSFENQNMHSKIEFLTQENKEMKDEIAKLNQNS 1199 Query: 1187 GHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQR 1246 G D N++++ +L+ + E L EN NL + +++S +++ + EI + L + Sbjct: 1200 GDDDYNKQEVIELRDENESLIHENSNLKLEIEKMKSKLTTFSPKEKVEILQQEIAQLTSK 1259 Query: 1247 EADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHL 1306 + ++ ++L+ S+F S Y LL + Q T ++ K++ V S NK + +E+L Sbjct: 1260 NKELEEEINQLKNNNSSFLS-YSSLLKTPQPQTSKKGIKLINTTSVLS-TNK-NESDENL 1316 Query: 1307 RNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQS 1366 NL E I + + E + +L+ +N+ + + Sbjct: 1317 ENLNESLLQTIENLRHENDNLTQENIKLKSQKSLKLLQDIKSQLELK-DNEINE--LKSK 1373 Query: 1367 ILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEA-KVLELTHQLELKDSEIYQKTHEYTI 1425 I +++E+N Q+ K + + + E K+LE + EL+ +I + Sbjct: 1374 INDLSEKNEQITKINESLQLRSSPTKTKSLELERDKLLERAAKAELELEDIKSRLD---- 1429 Query: 1426 TLTQRNDEFE---NVRQ-QLVEYEK-RIEDLTYEKESELAILRLKMHENANHYETMQKES 1480 +L + ND + + R+ + VE E+ + T + E +L + K+++ +++ Sbjct: 1430 SLAKENDTLKLRPSPRKVKSVEAERDNLLARTTKAELDLEDAKTKINDLTKENNILKQRP 1489 Query: 1481 EIERVKLIE-ELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDE 1539 + K I+ E + + + KQ+ E+ + + E E+ + L N + EI + + Sbjct: 1490 SPTKTKHIQIERDHLLDRATKAEKQLEEMKENISELSIAKEELDSQLANCQKEINRMTEV 1549 Query: 1540 ITNLQ---NMVRASSSKIQKHVSFASDTKQ 1566 NL+ N + S + K +S A D K+ Sbjct: 1550 DENLKKKLNDMDIISDAVSK-ISRAKDQKE 1578 Score = 165 bits (400), Expect = 1e-38 Identities = 316/1517 (20%), Positives = 642/1517 (42%), Gaps = 178/1517 (11%) Query: 143 DVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXX 202 ++ + + I +K+N + LQ ++ E +L KI E ++ AK T Sbjct: 302 ELLKIKSEIDDKNNEIKNLQQEISNFEEENANLNAKITELEK--SAKKSIQTISILEKEI 359 Query: 203 XXXXXXXXXEDTKQQMTKMQENFIAMEAEW------KDEKQRLLKDIESKDV---RISSL 253 E KQQ+TK + N + + K+E +L I V +++S+ Sbjct: 360 DDLSE----ELEKQQVTKTESNSDDFQKQVEAVRLVKEENDQLRDQINQLTVYKEKMNSI 415 Query: 254 EEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCE-EKTEIEE 312 + N+ L++ ++ E++ L +E E+ AK++++ E +K EI Sbjct: 416 LKENQNLKSEYIKMKDENTLLREENERIMEESNA--------AKENLKKENENQKNEISS 467 Query: 313 -KGSLEIANMTELTKKI--------ELLEHLNCQIRQTNKELENKLATMGTESKAVSSPS 363 E+ + E K+ E+++ LN ++ Q KE E + E K + + Sbjct: 468 LTNEDELYKLREENDKLIKSREAQNEIIQKLNNEMNQM-KEKEKDFDKLAQEKKLLKDEN 526 Query: 364 KKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVD 423 + LI+ S K K L++E +++ N+N+ L+ + LN++L Sbjct: 527 DR---LIN--SEMEELDKYKKENQDLNNELQRIKNERQENENKENNLKQGNEQLNEELQR 581 Query: 424 KEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIH--VGTNTEDVNEIAKV 481 + + K+ I +L+ + Q + + + ++ E + EI Sbjct: 582 TKQTVINKEEELKKVRDEADKLRKKIEELKEKQQNQINDNEELRKEIKSSEEKMKEIQSE 641 Query: 482 QEQLKQELNDEIKDV-NVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQM 540 E LK+++ E ++ N+ D ++KL + + + + ID N ++ N K +++ + Sbjct: 642 NEILKKQIEKEDENSSNISDDLQKLVNK----SLVKESID--ENNDVETIENLKKEIEDL 695 Query: 541 QKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYK 600 +K DNF +S N+++ E L + + ++ EE L+ +Y+ ++S + K Sbjct: 696 KKEKDNFDSISIENEDLRSQVEVLIKVEDERNQMSEELEKLR---ANYNE---LQSQISK 749 Query: 601 KMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIK 660 + EN ET I L +K L +EL ++ + D ++ + +++S+ S K Sbjct: 750 Q--NFENNKET----IEKLIGEKSKLQEELESIKNELDSIQ-----VEKIESENESSS-K 797 Query: 661 SVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDL 720 + L E+ID EL I N+ K L TI +++ E +++L+ +EN DL Sbjct: 798 IIALTEEID-------ELKNQINNISEQKSTLEFTIDEIKAQNESEISQLK---KENEDL 847 Query: 721 TDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICR 780 K+E +S E +EL +I + + S + + + +L N E+++ K ++ + Sbjct: 848 NSKIESLSKEN-NELKTEIENIQNSHSLSLLETEMNNKLTNL---NEENDMLKNENENIK 903 Query: 781 LEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQ 840 E+ + E++ SL+ D L + + + T + D+ + L + ++ + Sbjct: 904 REKEETLAENK--SLKDTLDFFEKNLTKINEQNKDKTEELDKQKRIVLTLTGENNELKSK 961 Query: 841 LLEIEHENKELQKKNQIL---LEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQ 897 L +I+++ + LQK+N+ L ++ QNL + L +M AL E E+ K + Sbjct: 962 LDKIKNDYELLQKENEKLESDIDNPQNLSL-LEEMNSKLTALTE----------ENKKLK 1010 Query: 898 TQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYV 957 ++ DL++ + + + H + LE E N+++ S + L ++ EK ++ Sbjct: 1011 EEIEDLQAENEALQNTHSLSL---------LETEMNSKLTSLTEENGKLKKENEK-LKID 1060 Query: 958 TQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINE----INK 1013 Q + +E K + L E+L K + EL Q T S E +N +++ Sbjct: 1061 LQNNSIEKELKLKLTKLTEENEKLGKESKELKQIIDQMNDTHSLSLLETEMNNKLASLSE 1120 Query: 1014 LNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLD 1073 N LK+++ ++ N+K S ++V +Y + + K+E++ E Q + ++ Sbjct: 1121 ENNKLKEENNKLTKSNEKAKTEYQSLKTIVDEYGNDYEEMKQKIEDLSFENQNMHSKIEF 1180 Query: 1074 SKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXX 1133 Q N+E++ D+I +L + + N K E + + E + + +N+ Sbjct: 1181 LTQENKEMK-------DEIAKLNQNSGDDDYN--KQEVIELRDENESLIHENSNLKLEIE 1231 Query: 1134 XXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQ 1193 +E+ E +LQ++ A+L ++ +E +I QL+ N+ + + Sbjct: 1232 KMKSKLTTFSPKEKVE------ILQQEIAQLTSKNKELEEEINQLKNNNSSFLSYSSL-- 1283 Query: 1194 EQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQ-READFQK 1252 LK+ Q + + L++T + L ++ + + D+ + E Q + R + Sbjct: 1284 -----LKTPQPQTSKKGIKLINTTSVLSTNKNES-DENLENLNESLLQTIENLRHENDNL 1337 Query: 1253 TEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEK 1312 T+ ++++ K +LL ++S + + N+I ++ S N L +K E + + E Sbjct: 1338 TQENIKLK----SQKSLKLLQDIKSQLELKDNEI---NELKSKINDLSEKNEQITKINES 1390 Query: 1313 YADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXD-LRTENQSYK-QMQEQSILNI 1370 + + E+E +K+ D L EN + K + + + ++ Sbjct: 1391 LQLRSSPTKTKSLELERDKLLERAAKAELELEDIKSRLDSLAKENDTLKLRPSPRKVKSV 1450 Query: 1371 NEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLE-LKDSEIYQKTHEYTITLTQ 1429 E L + + DA+ K+ +LT + LK KT I Sbjct: 1451 EAERDNLLARTTKAELD-------LEDAKTKINDLTKENNILKQRPSPTKTKHIQIERDH 1503 Query: 1430 RNDEFENVRQQLVEYEKRIEDLTYEKE---SELAILRLKMHENANHYETMQKE------- 1479 D +QL E ++ I +L+ KE S+LA + +++ E ++K+ Sbjct: 1504 LLDRATKAEKQLEEMKENISELSIAKEELDSQLANCQKEINRMTEVDENLKKKLNDMDII 1563 Query: 1480 ----SEIERVKLIEELNVKITESVSLNKQVAELNKALEEEV---------AKT-NEMQTA 1525 S+I R K +ELN KI E N+++ N L EE+ +KT E + Sbjct: 1564 SDAVSKISRAKDQKELNTKIEELQKENQKLQTKNAELAEEINSSKFSPRQSKTIQEFRQK 1623 Query: 1526 LENQEIEIVTLNDEITNLQ---NMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLD 1582 E E LN I+ L+ N S+ ++ +S + +Q+ + N++ Sbjct: 1624 FEEISKENEKLNKRISELEFERNSNNTSTKINRQKISELENINFSMQKQIVSLENEKKFT 1683 Query: 1583 AVPRAELDLAMYMLHQR 1599 AEL+ +L+ R Sbjct: 1684 KNKIAELENEKLILNNR 1700 Score = 149 bits (361), Expect = 6e-34 Identities = 243/1134 (21%), Positives = 498/1134 (43%), Gaps = 101/1134 (8%) Query: 496 VNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNK 555 +N DLIEKL+ A ++ +L EI+ ++ +++ K+ Q + N K SD N Sbjct: 119 LNHNDLIEKLEIASKENDELRKEIEGFHELSRSLQNQLDEKINQCDALV-NEKKSSDKN- 176 Query: 556 EIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKA 615 I +L +++ L + +LE + Q+ + + + ++ +D + + N + + Sbjct: 177 -IDQLKKQIEQLKSQF-KLETSRYEKQIDVYELELAKL--ADEHNNKNDQSNTSNSE-SE 231 Query: 616 ISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKS--VHLEEQIDALSA 673 I+ L+ Q L +L + K ED+L + +S + S +KS +L+EQ+ +LS Sbjct: 232 INKLKQQLIKLQNDLDEERVKSVATEDRLTKFRE-ESSKAISTLKSQNSNLQEQL-SLSK 289 Query: 674 SKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKM--SAEK 731 ++ A N +L K + I D N+ +++ ++ N+ +EN +L K+ ++ SA+K Sbjct: 290 IEQNSAQNAGNDELLK--IKSEIDDKNNEIKNLQQEISNFEEENANLNAKITELEKSAKK 347 Query: 732 ISELLAKINHEEQSKIQTQFGIDAKIQERDL-YIENIESELSKYKSRICRLEESIAVMED 790 + ++ + E + +++++ + E+ + K + ++E + D Sbjct: 348 SIQTISILEKEIDD-------LSEELEKQQVTKTESNSDDFQKQVEAVRLVKEENDQLRD 400 Query: 791 RRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVE-----KQLLEIE 845 + L +++ S L+E Q SEY +DE N L + +++R++E K+ L+ E Sbjct: 401 QINQLTVYKEKMNSILKENQNLKSEYIKMKDE--NTL-LREENERIMEESNAAKENLKKE 457 Query: 846 HENKE-----LQKKNQI--LLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQT 898 +EN++ L ++++ L EEN L S + L + N+ E + K Sbjct: 458 NENQKNEISSLTNEDELYKLREENDKLIKSREAQNEIIQKLNNEMNQMKEKEKDFDKLAQ 517 Query: 899 QLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVT 958 + + L+ R+ + + + KKE +DL N +++ I++++ NE E N++ Sbjct: 518 EKKLLKDENDRLINSEMEELDKYKKENQDL----NNELQ-RIKNERQENENKENNLKQGN 572 Query: 959 -QLEAQLQEYK----NNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINK 1013 QL +LQ K N E L +E +K+ + I++ +KQQ Q D E+ EI Sbjct: 573 EQLNEELQRTKQTVINKEEELKKVRDEADKLR-KKIEELKEKQQNQIND-NEELRKEIKS 630 Query: 1014 LNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEE-----MQRVS 1068 +K+ E L ++I + S +SD KL + E+++E ++ + Sbjct: 631 SEEKMKEIQSENEILKKQIEKEDEN-SSNISDDLQKLVNKSLVKESIDENNDVETIENLK 689 Query: 1069 KQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNV 1128 K++ D K+ + + E +D ++ E + E E +S +E + + N + Sbjct: 690 KEIEDLKKEKDNFDSISIENED-LRSQVEVLIKVE-----DERNQMSEELEKLRANYNEL 743 Query: 1129 DXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGH 1188 + E+ I E+S LQE+ + EL + I+ E E + Sbjct: 744 QSQISKQNFENNKETI---EKLIGEKSKLQEELESIKNELDSIQVEKIESE---NESSSK 797 Query: 1189 DVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAEL-WKQHLAQRE 1247 + E+I++LK+++ ++ + L T+ E+++ S + Q E +L K +E Sbjct: 798 IIALTEEIDELKNQINNISEQKSTLEFTIDEIKAQNESEISQLKKENEDLNSKIESLSKE 857 Query: 1248 ADFQKTEHELRVQ----LSAFESKYEQLLDSVQSST---QEETNKIVTMEQVTSLQNK-L 1299 + KTE E +Q LS E++ L ++ + E I ++ T +NK L Sbjct: 858 NNELKTEIE-NIQNSHSLSLLETEMNNKLTNLNEENDMLKNENENIKREKEETLAENKSL 916 Query: 1300 QDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSY 1359 +D + EK IN+ ++E D++ ++ + + Sbjct: 917 KDTLDFF----EKNLTKINEQNKDKTEELDKQKRIVLTLTGENNELKSKLDKIKNDYELL 972 Query: 1360 KQMQEQSILNI-NEENAQLKKSSXXXXXXXXXXXXRVND------AEAKVLELTHQLELK 1412 ++ E+ +I N +N L + ++ + AE + L+ TH L L Sbjct: 973 QKENEKLESDIDNPQNLSLLEEMNSKLTALTEENKKLKEEIEDLQAENEALQNTHSLSLL 1032 Query: 1413 DSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANH 1472 ++E+ K +LT+ N + + ++L + +++ + EKE +L + +L Sbjct: 1033 ETEMNSK----LTSLTEENGKLKKENEKL---KIDLQNNSIEKELKLKLTKLTEENEKLG 1085 Query: 1473 YETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIE 1532 E+ + + I+++ L++ TE + ++E N L+EE N++ + E + E Sbjct: 1086 KESKELKQIIDQMNDTHSLSLLETEMNNKLASLSEENNKLKEE---NNKLTKSNEKAKTE 1142 Query: 1533 IVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPR 1586 +L + N KI+ +SF + + E L NKE+ D + + Sbjct: 1143 YQSLKTIVDEYGNDYEEMKQKIE-DLSFENQNMHSKIEFLTQE-NKEMKDEIAK 1194 Score = 136 bits (329), Expect = 5e-30 Identities = 297/1509 (19%), Positives = 622/1509 (41%), Gaps = 139/1509 (9%) Query: 96 NTLKQKEILMEKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKD 155 N +K+KE +K+ Q K+L K + ++ ++ + N +E + Sbjct: 503 NQMKEKEKDFDKLAQEKKLLKDENDRLINSEMEELDKYKKENQDLNNELQRIKNERQENE 562 Query: 156 NALSVL-QVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDT 214 N + L Q ++ E Q IN+++++ + +++A ++ Sbjct: 563 NKENNLKQGNEQLNEELQRTKQTVINKEEELKKVRDEADKLRKKIEELKEKQQNQINDN- 621 Query: 215 KQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSL-EEANKLLEAARFEISLEHSK 273 +++ K ++ E + E + L K IE +D S++ ++ KL+ + + S++ + Sbjct: 622 -EELRKEIKSSEEKMKEIQSENEILKKQIEKEDENSSNISDDLQKLVNKSLVKESIDENN 680 Query: 274 LAQELEQXXXXXXXXXXXXXXLAKQSIE-PSCEEKTEIEEKGSLEIANMTELTKKIEL-L 331 + +E SIE + E+ K E M+E +K+ Sbjct: 681 DVETIENLKKEIEDLKKEKDNFDSISIENEDLRSQVEVLIKVEDERNQMSEELEKLRANY 740 Query: 332 EHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSS 391 L QI + N EN T+ K + SK L S K+ ++ K SS Sbjct: 741 NELQSQISKQN--FENNKETI---EKLIGEKSKLQEELESIKNELDSIQVEKIESENESS 795 Query: 392 E---TLNQDTDKKINK-NEIAKLEMVIQ-SLNKDLVDKEYVISE--KDTXXXXXXXXXXG 444 L ++ D+ N+ N I++ + ++ ++++ E IS+ K+ Sbjct: 796 SKIIALTEEIDELKNQINNISEQKSTLEFTIDEIKAQNESEISQLKKENEDLNSKIESLS 855 Query: 445 KDTLIAQLQLEHQQHMEGPSLIHVG-----TNTEDVNEIAKVQ-EQLKQEL------NDE 492 K+ + ++E+ Q+ SL+ TN + N++ K + E +K+E N Sbjct: 856 KENNELKTEIENIQNSHSLSLLETEMNNKLTNLNEENDMLKNENENIKREKEETLAENKS 915 Query: 493 IKDV------NV-------KDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQ 539 +KD N+ KD E+L + + L E + + K+K++++L K+ Sbjct: 916 LKDTLDFFEKNLTKINEQNKDKTEELDKQKRIVLTLTGENNELKSKLDKIKNDYELLQKE 975 Query: 540 MQKT---IDN---FSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQ----LHLVDYD 589 +K IDN S + + N ++ LTEE L +++ +L+ E LQ L L++ + Sbjct: 976 NEKLESDIDNPQNLSLLEEMNSKLTALTEENKKLKEEIEDLQAENEALQNTHSLSLLETE 1035 Query: 590 SGRMIES----------DVYKKMIEMENLA---ETRLKAISLLESQKFDLVQELHILQQK 636 + S + K I+++N + E +LK L E + L +E L+Q Sbjct: 1036 MNSKLTSLTEENGKLKKENEKLKIDLQNNSIEKELKLKLTKLTEENE-KLGKESKELKQI 1094 Query: 637 YDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTI 696 D++ D + +S L+++ K L E+ + L +L E K + + L + Sbjct: 1095 IDQMNDTHS-LSLLETEM---NNKLASLSEENNKLKEENNKLTKSNEKAKTEYQSLKTIV 1150 Query: 697 KDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAE--KISELLAKIN-------HEEQSKI 747 + ND E++ K+++ EN ++ K+E ++ E ++ + +AK+N + +Q I Sbjct: 1151 DEYGNDYEEMKQKIEDLSFENQNMHSKIEFLTQENKEMKDEIAKLNQNSGDDDYNKQEVI 1210 Query: 748 QTQFGIDAKIQERD---LYIENIESELSKY--KSRICRLEESIAVMEDRRYSLERKADQL 802 + + ++ I E L IE ++S+L+ + K ++ L++ IA + + LE + +QL Sbjct: 1211 ELRDENESLIHENSNLKLEIEKMKSKLTTFSPKEKVEILQQEIAQLTSKNKELEEEINQL 1270 Query: 803 ----GSYLQEKQ--KAYSEYTIQED-ELVNRLAVLM----DHDRVVEK------QLLE-I 844 S+L K T ++ +L+N +VL + D +E Q +E + Sbjct: 1271 KNNNSSFLSYSSLLKTPQPQTSKKGIKLINTTSVLSTNKNESDENLENLNESLLQTIENL 1330 Query: 845 EHENKELQKKN-----QILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQT- 898 HEN L ++N Q L+ Q+++ L N L K N + TK Sbjct: 1331 RHENDNLTQENIKLKSQKSLKLLQDIKSQLELKDNEINELKSKINDLSEKNEQITKINES 1390 Query: 899 -QLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYV 957 QLR + K + E L+ + K +LE + ++++S ++ L K + V Sbjct: 1391 LQLRSSPTKTKSLELERDKLLERAAKAELELE-DIKSRLDSLAKENDTL--KLRPSPRKV 1447 Query: 958 TQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNAL 1017 +EA+ +++E+ +L ++ +Q SP T+ E + L Sbjct: 1448 KSVEAERDNLLARTTKAELDLEDAKTKINDLTKENNILKQRPSPTKTKHIQIERDHLLDR 1507 Query: 1018 LKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQH 1077 + ++++ + + I+ ++ + +S+LA ++ M E + + K+L D Sbjct: 1508 ATKAEKQLEEMKENISELSIAK----EELDSQLANCQKEINRMTEVDENLKKKLNDMDII 1563 Query: 1078 NEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXX 1137 ++ + + R +D + K +L E +T+ ++ E ++ + Sbjct: 1564 SDAVSKISRAKDQKELNTKIEELQKENQKLQTKNAELA---EEINSSKFSPRQSKTIQEF 1620 Query: 1138 XXXXLKVQEEEEFIQER-SVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQI 1196 ++ +E E + +R S L+ + NT + KI +LE +N + V + + Sbjct: 1621 RQKFEEISKENEKLNKRISELEFERNSNNTSTKINRQKISELENINFSMQKQIVSLENEK 1680 Query: 1197 NQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHE 1256 K+K+ +L EN+ L+ L + I S + + E+ + ++Q + T + Sbjct: 1681 KFTKNKIAEL--ENEKLI-----LNNRIDSLISNKSSPENEI--RQMSQTIEGLKNTITD 1731 Query: 1257 LRVQLSAFESKYEQLLDSVQSSTQEETNKIVTM-EQVTSLQNKLQDKEEHLRNLQEKYAD 1315 L Q+ + + + L +S EE+ + + E++ L+ +L + L N K +D Sbjct: 1732 LTKQIRKLQKENDTLRESSMMIAGEESKEETKLKEEIAELKFRLSQMQSELINANSKLSD 1791 Query: 1316 VINQIEILRSEIEDE--KVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEE 1373 I+ S DE K + +NQ+ K +Q+ E Sbjct: 1792 AISSDRQNFSNNTDEVTKANENKIKSLNTKLKKLSEEKKKLQNQNNKLLQDLEKFRSEYE 1851 Query: 1374 NAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDE 1433 N + + + ++ + + L + +E+ Q + + TL ++ Sbjct: 1852 NIRSFIDQKGDKEQKDEEYTLLQEKYIQLQKESISLNSQLNEL-QSSRKTIRTLQRKLKS 1910 Query: 1434 FENVRQQLVEYEKRIEDLTYEKESELAILRLK----MHENANHYETMQKESEIERVKLIE 1489 EN ++E ++ ++ + +L LK ++ A+ + Q S+ + +KL+ Sbjct: 1911 LENNANSIMETDRHCHCSEALEQFKQEVLELKEIILKNDEASSKISKQISSQSDEIKLL- 1969 Query: 1490 ELNVKITES 1498 ++ K+T+S Sbjct: 1970 RIHSKVTDS 1978 Score = 70.1 bits (164), Expect = 5e-10 Identities = 133/665 (20%), Positives = 283/665 (42%), Gaps = 67/665 (10%) Query: 957 VTQLEAQLQEYKNNIENLNM-NVEELNKMNLELIDKH-------VQKQQTQSPDYTEQYI 1008 VT+L+ QL YK I++L + N EE+ ++ ++I K+ + K T S + + Sbjct: 41 VTELQNQLFNYKMKIDDLRIHNNEEIIRLK-KIIAKYEGPSNEILTKNSTSSSNSSLSPN 99 Query: 1009 NEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESK----LAQFTTKLENMEEEM 1064 + + N D LN ++ S +D K + + L+N +E Sbjct: 100 SPSREGNLARSLIDSSSSFLNHNDLIEKLEIASKENDELRKEIEGFHELSRSLQNQLDEK 159 Query: 1065 QRVSKQLLDSKQHNEELQILVREQDDQIK---ELKETKLTFEMNIPKTEGMIISSTIEPM 1121 L++ K+ +++ +++Q +Q+K +L+ ++ ++++ + E ++ Sbjct: 160 INQCDALVNEKKSSDKNIDQLKKQIEQLKSQFKLETSRYEKQIDVYELELAKLADEHNNK 219 Query: 1122 SDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETL 1181 +D +N + +K+Q + + + +SV E +L +E I L++ Sbjct: 220 NDQSNTSNSESEINKLKQQLIKLQNDLDEERVKSVATED--RLTKFREESSKAISTLKSQ 277 Query: 1182 NTELTGHDVVNQEQINQLKSKLEQ---LNTENDNLLSTVAELRSSISSAVD-QRGFEIAE 1237 N+ L QEQ++ SK+EQ N ND LL +E+ + + Q+ E Sbjct: 278 NSNL-------QEQLS--LSKIEQNSAQNAGNDELLKIKSEIDDKNNEIKNLQQEISNFE 328 Query: 1238 LWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSV--QSSTQEETNKIVTMEQVTSL 1295 +L + + +K+ + +S E + + L + + Q T+ E+N +QV ++ Sbjct: 329 EENANLNAKITELEKSAKKSIQTISILEKEIDDLSEELEKQQVTKTESNSDDFQKQVEAV 388 Query: 1296 Q------NKLQDKEEHLRNLQEKYADVINQIEILRSE---IEDEKVAFXXXXXXXXXXXX 1346 + ++L+D+ L +EK ++ + + L+SE ++DE Sbjct: 389 RLVKEENDQLRDQINQLTVYKEKMNSILKENQNLKSEYIKMKDENTLLREENERIMEESN 448 Query: 1347 XXXXDLRTENQSYKQ-----MQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAK 1401 +L+ EN++ K E + + EEN +L KS N+ K Sbjct: 449 AAKENLKKENENQKNEISSLTNEDELYKLREENDKLIKSREAQ-----------NEIIQK 497 Query: 1402 VLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVR-QQLVEYEKRIEDLTYEKESELA 1460 + +Q++ K+ + + K + L ND N ++L +Y+K +DL +EL Sbjct: 498 LNNEMNQMKEKEKD-FDKLAQEKKLLKDENDRLINSEMEELDKYKKENQDL----NNELQ 552 Query: 1461 ILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEE-EVAKT 1519 ++ + EN N +++ +E +L I + L K E +K ++ E K Sbjct: 553 RIKNERQENENKENNLKQGNEQLNEELQRTKQTVINKEEELKKVRDEADKLRKKIEELKE 612 Query: 1520 NEMQTALENQEI--EIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMN 1577 + +N+E+ EI + +++ +Q+ +I+K +S+ + ++ ++ Sbjct: 613 KQQNQINDNEELRKEIKSSEEKMKEIQSENEILKKQIEKEDENSSNISDDLQKLVNKSLV 672 Query: 1578 KELLD 1582 KE +D Sbjct: 673 KESID 677 Score = 42.3 bits (95), Expect = 0.11 Identities = 42/173 (24%), Positives = 81/173 (46%), Gaps = 10/173 (5%) Query: 1421 HEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKES 1480 HE + +L + DE N LV +K + + + ++ L+ + + YE Sbjct: 146 HELSRSLQNQLDEKINQCDALVNEKKSSDKNIDQLKKQIEQLKSQFKLETSRYEKQIDVY 205 Query: 1481 EIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEI 1540 E+E KL +E N K +S + N + +E+NK L++++ K +Q L+ + ++ V D + Sbjct: 206 ELELAKLADEHNNKNDQSNTSNSE-SEINK-LKQQLIK---LQNDLDEERVKSVATEDRL 260 Query: 1541 TNL-QNMVRASSSKIQKHVSFASDTKQGRDEQ--LDNTMNKELLDAVPRAELD 1590 T + +A S+ ++ + + EQ N N ELL ++E+D Sbjct: 261 TKFREESSKAISTLKSQNSNLQEQLSLSKIEQNSAQNAGNDELLKI--KSEID 311 >UniRef50_Q237L2 Cluster: Kinesin motor domain containing protein; n=2; Tetrahymena thermophila|Rep: Kinesin motor domain containing protein - Tetrahymena thermophila SB210 Length = 2307 Score = 177 bits (430), Expect = 3e-42 Identities = 286/1451 (19%), Positives = 635/1451 (43%), Gaps = 145/1451 (9%) Query: 147 LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINE---KDQIIEAKNKATTXXXXXXXXX 203 L + KD+ + +++ + M I++LQE +N+ Q +E + Sbjct: 433 LQQELDGKDDQIHKMEIFQQQMVKKIMELQEDLNKVKLDKQELEGSQRHLKQSLCQGVKQ 492 Query: 204 XXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAA 263 + K ++ +++ + + + ++E + L++ + + EE ++L E Sbjct: 493 QDTIVLLEQQKKVEVENIEKKYQELLKQTENELKSFLEEFDKTSLEYE--EEIDQLKE-- 548 Query: 264 RFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTE 323 ++ K Q++E ++ + K EK + E E Sbjct: 549 ------QNIKYLQDIENYAKQTESLNDQLKQKNEEIVNLENTYKNLESEKENSE-QQFIE 601 Query: 324 LTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMK 383 L+++ +L+++ + R+ N + + K+ K + S K + + +K Sbjct: 602 LSQQFKLIDN-GYKEREENYKKQIKMNEQKASLKEKENVSLKEQLKQQENAQSQALNTLK 660 Query: 384 SPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNK-DLVDKEYVISEKDTXXXXXXXXX 442 +LS + N+ +++NK I+ E Q L + D+V EY S+ D Sbjct: 661 EEIQELSKQ--NKVLQEELNKKTISISEREKQHLQELDIVKSEYT-SQFDYLNSERESLK 717 Query: 443 XGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLI 502 + L+ E +Q E + +++ E K+ + +E + ++ + +K + Sbjct: 718 SSLEKGRVDLEQELKQARE-----QIEKQKQEIVEYEKIVNESNEEKSMMMQQLEIK-ID 771 Query: 503 EKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTE 562 E ++ + +I + ++ ++ + K++++ L + + +++ + E ++ + Sbjct: 772 ELIQHNKREIASMKKQLTEKDQYIQNQKNSYEQLLNKYNELQEDYEDCQEQQSEEIQKNK 831 Query: 563 ELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEM--ENLAETRLKAISLLE 620 L + +K +L++ + L+ L DYD +S Y+ IE +N+ + K L+E Sbjct: 832 NL--IKEKEEKLQQVQQQLEEQLQDYDQ----KSSSYQSQIEQLNQNIEQLNQKIEQLIE 885 Query: 621 SQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELAL 680 QK + + I ++Y + D+ L IK+ + Q +A+ K+ Sbjct: 886 -QKQQMESQFEIDIEQYKNKNQQ--DLENL-------NIKTAQSQLQSEAI---LKQFNQ 932 Query: 681 VIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISEL-LAKI 739 IE L L Q K+ ++ K + I++ + DKL +E+ S+L L +I Sbjct: 933 QIEQLNLTNSQ-----------KDQLIAKQKEQIEQQTEQLDKLNTELSEQSSQLSLIQI 981 Query: 740 NHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKA 799 N++E IQ + ++ + + + + +++ K I L + I DR+ +E Sbjct: 982 NNQELI-IQLD-ETEKQLNTQKQQLNHSQQQITDLKKEISILNQEIF---DRKKEIESYV 1036 Query: 800 DQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILL 859 + Q+ ++ E ++E + N + D ++++ L++ + + +EL++ + ++ Sbjct: 1037 KSNNQFEQKIEQLKQEIVVKEFQHENEIQEKKD---MLQEHLIQFKDKEEELKQAREDII 1093 Query: 860 EENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIV 919 E + ++ L +Q + L +K + + ++ K + QL + +++ + Q+ + Sbjct: 1094 NEKNSFEVVLKSIQNQNSELEQK-----IVDLKNDKERLQL--IVEEKEKVILDLQSQLQ 1146 Query: 920 QKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVE 979 +K +I+ + E +++IE+A+ K +++I+ + Q+++ NN+++ +++E Sbjct: 1147 EKCSQIQQIS-EISSEIETALEQK-------QQHIQLLLLKNTQVEDQINNLKDQILDLE 1198 Query: 980 ELNKMNLEL---IDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQ 1036 E+NK N+E + +Q++ Q + EQ ++ +LNA + Q ++E L KINN Q Sbjct: 1199 EINKQNVEKQENLQTQLQQKSIQQQEQNEQNAEQVCQLNAQIAQLNQE---LEDKINNLQ 1255 Query: 1037 VSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHN-EELQILVREQDDQIKEL 1095 KL Q T L+ + E K++LD+K + E L++ ++ + + EL Sbjct: 1256 ------------KLNQ--TYLDQIRE-----IKEILDAKNNEIESLKLSQQQIELSMGEL 1296 Query: 1096 KETKLTFEMNIPK--TEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQE 1153 K E N+ + TE + I+ +++ AN + L +E Q Sbjct: 1297 KSIFEESESNLQQKNTENENLKDKIKELTEKANEYENEMKEQNDEINQLTESNKEIQGQL 1356 Query: 1154 RSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNL 1213 +S ++ + +L + QE QL+ ++ + +NQ Q +++ K+ Q+ E +N Sbjct: 1357 QSEIENLNQQLESHQQEIAELKGQLDIQIQLVSEGENLNQNQQLEIEQKIAQM-IEQENQ 1415 Query: 1214 LSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLD 1273 + +L++ I+ ++R I L KQ A+++A +K E E++ E + ++ Sbjct: 1416 VKQF-QLKAQIN---EER---IMILEKQVQAKQQAIEEKME-EIKKHKENVEQVLQTEIN 1467 Query: 1274 SVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQE-KYADVINQIEILRSEIEDEKV 1332 QS E K + E SLQ +L+D+ E + N E K +IE L+++ ED Sbjct: 1468 DKQSIINEYQEKFIEQE---SLQKQLEDQIEQIVNQYEVKLETKQTEIEELQNQYEDLHN 1524 Query: 1333 AFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEE---NAQLKKSSXXXXXXXX 1389 F L ++N+ K+ E N+NE+ Q K+ Sbjct: 1525 QFEAFQQESNEQFQFNIKKLESQNEELKEQIE----NLNEKMCLEIQDKEQQKQNNENLL 1580 Query: 1390 XXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDE-FENVRQQLVEYEKRI 1448 + D +K +E + + + + ++ + L +N + E ++Q +E K+I Sbjct: 1581 SQIQSIKDENSKKIEELELIIISEKQQVEQLNLKISDLNLQNQKLLEQLKQVELENAKKI 1640 Query: 1449 EDLTYEKESELAILRLKMHENA-----NHYETMQKESEIERVKLIEELNVKITE-SVSLN 1502 +L + E ++ ++ ++ + + N + +QK+ I+R + +L +K + + N Sbjct: 1641 NNLQIDLEDKINLIHVQTQQLSCMIIQNAFRRIQKQKIIKR--YLNQLALKTRKLNAEQN 1698 Query: 1503 K-QVAEL-NKALEEEVAKTNEMQTALENQEIEIVTLNDEIT---NLQNMVRASSSKIQKH 1557 K + AE+ NK +++ E+ T L+ Q ++ NDEI Q+ + + K K Sbjct: 1699 KLEQAEIENKKQYDQLLYQAELDTYLQEQIKKLNEQNDEINQRIQQQDQILQENEKQLKK 1758 Query: 1558 VSFA--SDTKQ 1566 + SDT+Q Sbjct: 1759 LQIEKDSDTQQ 1769 Score = 158 bits (383), Expect = 1e-36 Identities = 259/1187 (21%), Positives = 518/1187 (43%), Gaps = 141/1187 (11%) Query: 484 QLKQELN---DEIKDVNV--KDLIEKLKSAEEQITQLN---DEIDAANKNMIK-----VK 530 QL+QEL+ D+I + + + +++K+ +E + ++ E++ + +++ + VK Sbjct: 432 QLQQELDGKDDQIHKMEIFQQQMVKKIMELQEDLNKVKLDKQELEGSQRHLKQSLCQGVK 491 Query: 531 SNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEE-----LHHLSQKVAELEEEKGNLQLHL 585 + L + QK ++ + +E+++ TE L + E EEE L+ Sbjct: 492 QQDTIVLLEQQKKVE-VENIEKKYQELLKQTENELKSFLEEFDKTSLEYEEEIDQLKEQN 550 Query: 586 VDYDSGRMIESDVYKKMIE-MENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKL 644 + Y + + + Y K E + + + + + I LE+ +L E +Q++ E+ + Sbjct: 551 IKY----LQDIENYAKQTESLNDQLKQKNEEIVNLENTYKNLESEKENSEQQFIELSQQF 606 Query: 645 ADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKE 704 I ++ + K + + EQ AS KE EN+ L KEQL K EN + Sbjct: 607 KLIDNGYKEREENYKKQIKMNEQ----KASLKEK----ENVSL-KEQL----KQQENAQS 653 Query: 705 DIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYI 764 +N L+ IQE K K+ E++++ I+ E+ +Q +D E Sbjct: 654 QALNTLKEEIQE----LSKQNKVLQEELNKKTISISEREKQHLQE---LDIVKSEYTSQF 706 Query: 765 ENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELV 824 + + SE KS LE+ +E + ++ + E +K +E ++ ++ Sbjct: 707 DYLNSERESLKSS---LEKGRVDLEQELKQAREQIEKQKQEIVEYEKIVNESNEEKSMMM 763 Query: 825 NRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKAN 884 +L + +D +++ EI K+L +K+Q + QN + S + YN L E Sbjct: 764 QQLEIKIDE--LIQHNKREIASMKKQLTEKDQYI----QNQKNSYEQLLNKYNELQEDYE 817 Query: 885 RTDLAESEST-KYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDK 943 +SE K + +++ E L+++ Q + ++ ++ + + +QIE ++ Sbjct: 818 DCQEQQSEEIQKNKNLIKEKEEKLQQV----QQQLEEQLQDYDQKSSSYQSQIEQLNQNI 873 Query: 944 KVLNEKYEKNIEYVTQLEAQLQEYKNNIENL-NMNVEELNKMNLELIDKHVQKQQTQSPD 1002 + LN+K E+ IE Q+E+Q ++ +IE N N ++L +N++ + Q QS Sbjct: 874 EQLNQKIEQLIEQKQQMESQ---FEIDIEQYKNKNQQDLENLNIK-----TAQSQLQSEA 925 Query: 1003 YTEQYINEINKLNALLKQKDEEIIALNQKI--NNAQVSYMSM-VSDYESKLA-------Q 1052 +Q+ +I +LN QKD+ I ++I Q+ ++ +S+ S+L+ + Sbjct: 926 ILKQFNQQIEQLNLTNSQKDQLIAKQKEQIEQQTEQLDKLNTELSEQSSQLSLIQINNQE 985 Query: 1053 FTTKLENMEEEMQRVSKQLLDSKQH----NEELQILVREQDDQIKELK---ETKLTFEMN 1105 +L+ E+++ +QL S+Q +E+ IL +E D+ KE++ ++ FE Sbjct: 986 LIIQLDETEKQLNTQKQQLNHSQQQITDLKKEISILNQEIFDRKKEIESYVKSNNQFEQK 1045 Query: 1106 IPKTEGMIISSTIE---PMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSA 1162 I + + I+ + + + + + LK Q E+ I E++ + Sbjct: 1046 IEQLKQEIVVKEFQHENEIQEKKDMLQEHLIQFKDKEEELK-QAREDIINEKNSFEVVLK 1104 Query: 1163 KLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRS 1222 + + E KI+ L+ L ++ I L+S+L+ E + + ++E+ S Sbjct: 1105 SIQNQNSELEQKIVDLKNDKERLQLIVEEKEKVILDLQSQLQ----EKCSQIQQISEISS 1160 Query: 1223 SISSAVDQRGFEI-AELWKQHLAQREADFQKTE----HELRVQ-LSAFESKYEQLLD-SV 1275 I +A++Q+ I L K + + + K + E+ Q + E+ QL S+ Sbjct: 1161 EIETALEQKQQHIQLLLLKNTQVEDQINNLKDQILDLEEINKQNVEKQENLQTQLQQKSI 1220 Query: 1276 QSSTQEETNKIVTME---QVTSLQNKLQDKEEHLRNLQEKYADVINQI-EIL---RSEIE 1328 Q Q E N + Q+ L +L+DK +L+ L + Y D I +I EIL +EIE Sbjct: 1221 QQQEQNEQNAEQVCQLNAQIAQLNQELEDKINNLQKLNQTYLDQIREIKEILDAKNNEIE 1280 Query: 1329 DEKVA---FXXXXXXXXXXXXXXXXDLR---TENQSYKQMQEQSILNINEENAQLKKSSX 1382 K++ +L+ TEN++ K ++ NE ++K+ + Sbjct: 1281 SLKLSQQQIELSMGELKSIFEESESNLQQKNTENENLKDKIKELTEKANEYENEMKEQND 1340 Query: 1383 XXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQ-QL 1441 ++++ L QLE EI + + I + Q E EN+ Q Q Sbjct: 1341 EINQLTESNKEIQGQLQSEIENLNQQLESHQQEIAELKGQLDIQI-QLVSEGENLNQNQQ 1399 Query: 1442 VEYEKRIEDLTYEKESELAILRLKMHENANHYETMQK---------ESEIERVKLIEE-- 1490 +E E++I + E+E+++ +LK N ++K E ++E +K +E Sbjct: 1400 LEIEQKIAQM-IEQENQVKQFQLKAQINEERIMILEKQVQAKQQAIEEKMEEIKKHKENV 1458 Query: 1491 ---LNVKITESVSLNKQVAE-------LNKALEEEVAK-TNEMQTALENQEIEIVTLNDE 1539 L +I + S+ + E L K LE+++ + N+ + LE ++ EI L ++ Sbjct: 1459 EQVLQTEINDKQSIINEYQEKFIEQESLQKQLEDQIEQIVNQYEVKLETKQTEIEELQNQ 1518 Query: 1540 ITNLQNMVRA----SSSKIQKHVSFASDTKQGRDEQLDNTMNKELLD 1582 +L N A S+ + Q ++ + EQ++N K L+ Sbjct: 1519 YEDLHNQFEAFQQESNEQFQFNIKKLESQNEELKEQIENLNEKMCLE 1565 Score = 149 bits (360), Expect = 8e-34 Identities = 257/1414 (18%), Positives = 603/1414 (42%), Gaps = 89/1414 (6%) Query: 212 EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271 + +QQ+ + +++ + ++ + ++L ++IE + +I L E + +E+ +FEI +E Sbjct: 842 QQVQQQLEEQLQDYDQKSSSYQSQIEQLNQNIEQLNQKIEQLIEQKQQMES-QFEIDIEQ 900 Query: 272 --SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIE 329 +K Q+LE + KQ + + +K L ++ ++ E Sbjct: 901 YKNKNQQDLENLNIKTAQSQLQSEAILKQFNQQIEQLNLTNSQKDQLIAKQKEQIEQQTE 960 Query: 330 LLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASK----MKSP 385 L+ LN ++ + + +L L + + + + L ++K N + + +K Sbjct: 961 QLDKLNTELSEQSSQLS--LIQINNQELIIQLDETE-KQLNTQKQQLNHSQQQITDLKKE 1017 Query: 386 WSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYV----ISEKDTXXXXXXXX 441 S L+ E ++ + + + E I+ L +++V KE+ I EK Sbjct: 1018 ISILNQEIFDRKKEIESYVKSNNQFEQKIEQLKQEIVVKEFQHENEIQEKKDMLQEHLIQ 1077 Query: 442 XXGKDTLIAQLQ---LEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQ-ELNDEIKDVN 497 K+ + Q + + + E N+E +I ++ ++ +L E K+ Sbjct: 1078 FKDKEEELKQAREDIINEKNSFEVVLKSIQNQNSELEQKIVDLKNDKERLQLIVEEKEKV 1137 Query: 498 VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNH-KLKLKQMQKTIDNFSKVSDSNKE 556 + DL +L+ QI Q++ EI + + ++ K H +L L + + D + + D + Sbjct: 1138 ILDLQSQLQEKCSQIQQIS-EISSEIETALEQKQQHIQLLLLKNTQVEDQINNLKDQILD 1196 Query: 557 IVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAI 616 + + ++ + + ++K Q + ++ ++ + + + E E ++ + Sbjct: 1197 LEEINKQNVEKQENLQTQLQQKSIQQQEQNEQNAEQVCQLNAQIAQLNQE--LEDKINNL 1254 Query: 617 SLLESQKFDLVQEL-HILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASK 675 L D ++E+ IL K +E+E +SQ Q + E+KS+ EE L Sbjct: 1255 QKLNQTYLDQIREIKEILDAKNNEIES--LKLSQQQIELSMGELKSI-FEESESNLQQKN 1311 Query: 676 KELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISEL 735 E ENLK ++L + EN+ ++ +++ + N ++ +L+ E +++ Sbjct: 1312 TEN----ENLKDKIKELTEKANEYENEMKEQNDEINQLTESNKEIQGQLQS-EIENLNQQ 1366 Query: 736 LAKINHEEQSKIQTQFGIDAKI--------QERDLYIENIESELSKYKSRICRLEESIAV 787 L + +E ++++ Q I ++ Q + L IE +++ + ++++ + + + Sbjct: 1367 LES-HQQEIAELKGQLDIQIQLVSEGENLNQNQQLEIEQKIAQMIEQENQVKQFQLKAQI 1425 Query: 788 MEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVV-EKQLLEIEH 846 E+R LE++ ++EK + ++ ++++ + D ++ E Q IE Sbjct: 1426 NEERIMILEKQVQAKQQAIEEKMEEIKKHKENVEQVLQ--TEINDKQSIINEYQEKFIEQ 1483 Query: 847 ENKELQKKNQILLEENQ---NLQISLSDMQQHYNALVEKANRTDLAESESTK-YQTQLRD 902 E+ + Q ++QI NQ L+ +++++ N + N+ + + ES + +Q ++ Sbjct: 1484 ESLQKQLEDQIEQIVNQYEVKLETKQTEIEELQNQYEDLHNQFEAFQQESNEQFQFNIKK 1543 Query: 903 LESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEA 962 LES + + + + L + EI+D E + E+ + + + ++ K IE +LE Sbjct: 1544 LESQNEELKEQIENLNEKMCLEIQDKEQQKQNN-ENLLSQIQSIKDENSKKIE---ELEL 1599 Query: 963 QLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKD 1022 + K +E LN+ + +LN N +L+++ Q + + I+ +K+N + Q Sbjct: 1600 IIISEKQQVEQLNLKISDLNLQNQKLLEQLKQVELENAKKINNLQIDLEDKINLIHVQTQ 1659 Query: 1023 EE--IIALN--QKINNAQV--SYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQ 1076 + +I N ++I ++ Y++ ++ KL KLE E E ++ QLL + Sbjct: 1660 QLSCMIIQNAFRRIQKQKIIKRYLNQLALKTRKLNAEQNKLEQAEIENKKQYDQLLYQAE 1719 Query: 1077 HNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXX 1136 + LQ +++ ++Q E+ + + + + E + IE S D ++ Sbjct: 1720 LDTYLQEQIKKLNEQNDEINQRIQQQDQILQENEKQLKKLQIEKDS-DTQQMNFYIEKIS 1778 Query: 1137 XXXXXLKVQEEE--EFIQERSVLQEQSAKLNTELQECYTKIIQLETL--NTELTGHDVVN 1192 +K +EE+ + E S L +Q ++E ++ ++++ N + + Sbjct: 1779 NLNQDIKAKEEQLAQSYDELSNLSKQLRICTNSVEELQFQLKNIKSVHDNIDFKVRKIQI 1838 Query: 1193 QEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQK 1252 Q + L+ +L + N+ L V +L ++ + + E + KQ L Q + D Q Sbjct: 1839 TFQKHLLRKELNAAISNNEQLQQNVDDLIQK-NTLLQYQNEEFSITNKQALDQIQ-DEQN 1896 Query: 1253 TEHELRVQLSAFES---KYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNL 1309 EL+++L + K +Q+++ +++ E NKI+ +EQ+ + +++ N Sbjct: 1897 KIVELQLELKEKNTCIEKVQQMIEKRETNLTELENKIINLEQLQKENQVIINQQFKQLNE 1956 Query: 1310 QEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTE--NQSYKQMQEQSI 1367 Q +N I ++ I +K + + E ++ Q + Sbjct: 1957 QNYKFKCMNSIRVISKFIAQKKWQQTVKKLMGAFAIQKIHFEKQIEVLDEKVAGYQIMKL 2016 Query: 1368 LNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITL 1427 L QL + + + +++V E + K S++Y++ E + Sbjct: 2017 LKQRVSEQQLNQYNRLIIERQKT----IEFLQSQV-EKEQYIFRKASQVYER--EVSARK 2069 Query: 1428 TQRNDEFENVRQQLVEYEKRIEDL---TYEKESELAILRLKMHENANHYETMQKESEIER 1484 Q V Q L Y+++I++L Y+ + ++ L+ ++++ ++ E E E+ Sbjct: 2070 IQSAYRLFKVNQILYRYKQQIDNLRKINYDYKEKIDRLQEQLYD-------LEDEIEKEK 2122 Query: 1485 VKLIEELNVKI-TESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNL 1543 + ++ N ++ E L + + LN ++ + + + + + TL ++ L Sbjct: 2123 SVISQQQNEQVFQERGFLQENINLLNTEFKKNEPQRGSRENQISSLQKSEKTLKQKLKEL 2182 Query: 1544 QNMVRASSSKIQ-KHVSFASDTKQGRDEQLDNTM 1576 + + ++ KH+ D KQ E + T+ Sbjct: 2183 DQSWKNQYTHLENKHLELQKD-KQILTESYEQTL 2215 Score = 96.3 bits (229), Expect = 6e-18 Identities = 190/938 (20%), Positives = 403/938 (42%), Gaps = 90/938 (9%) Query: 153 EKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXE 212 E++N + Q+K +I E I+ L++++ K Q IE K + Sbjct: 1411 EQENQVKQFQLKAQINEERIMILEKQVQAKQQAIEEKMEEIKKHKENVEQVLQTEI---N 1467 Query: 213 DTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHS 272 D + + + QE FI E+ K + ++ + + +V++ + + + L+ ++ + Sbjct: 1468 DKQSIINEYQEKFIEQESLQKQLEDQIEQIVNQYEVKLETKQTEIEELQNQYEDLHNQFE 1527 Query: 273 KLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIE-LL 331 QE + K+ IE + EK LEI + + + E LL Sbjct: 1528 AFQQESNEQFQFNIKKLESQNEELKEQIE-------NLNEKMCLEIQDKEQQKQNNENLL 1580 Query: 332 EHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSS 391 + + +K++E + +E + V + K S L + K + Sbjct: 1581 SQIQSIKDENSKKIEELELIIISEKQQVEQLNLKISDLNLQNQKLLEQLKQVELENAKKI 1640 Query: 392 ETLNQDTDKKINKNEIAKLE---MVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTL 448 L D + KIN + + M+IQ+ + + K+ +I + Sbjct: 1641 NNLQIDLEDKINLIHVQTQQLSCMIIQNAFRR-IQKQKIIKRYLNQLALKTRKLNAEQNK 1699 Query: 449 IAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSA 508 + Q ++E+++ + L +T +I K+ EQ NDEI ++ + L+ Sbjct: 1700 LEQAEIENKKQYD-QLLYQAELDTYLQEQIKKLNEQ-----NDEINQ-RIQQQDQILQEN 1752 Query: 509 EEQITQLNDEIDAANKNM---IKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELH 565 E+Q+ +L E D+ + M I+ SN +K ++ +++ S E+ L+++L Sbjct: 1753 EKQLKKLQIEKDSDTQQMNFYIEKISNLNQDIKAKEE------QLAQSYDELSNLSKQLR 1806 Query: 566 HLSQKVAELEEEKGNLQ-LH-LVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQK 623 + V EL+ + N++ +H +D+ R I+ K ++ E + L+ Sbjct: 1807 ICTNSVEELQFQLKNIKSVHDNIDFKV-RKIQITFQKHLLRKE--LNAAISNNEQLQQNV 1863 Query: 624 FDLVQELHILQQKYDE--VEDKLADISQLQSDQVCSEIKSVHLE--------EQIDALSA 673 DL+Q+ +LQ + +E + +K A + Q+Q +Q ++I + LE E++ + Sbjct: 1864 DDLIQKNTLLQYQNEEFSITNKQA-LDQIQDEQ--NKIVELQLELKEKNTCIEKVQQMIE 1920 Query: 674 SKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEK-- 731 ++ +EN ++ EQL + + N + +N+ QNY + M+ + K A+K Sbjct: 1921 KRETNLTELENKIINLEQLQKENQVIINQQFKQLNE-QNYKFKCMNSIRVISKFIAQKKW 1979 Query: 732 ---ISELLA-----KINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEE 783 + +L+ KI+ E+Q ++ + +I + L E +L++Y I ++ Sbjct: 1980 QQTVKKLMGAFAIQKIHFEKQIEVLDEKVAGYQIMKL-LKQRVSEQQLNQYNRLIIERQK 2038 Query: 784 SIAVME---DRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQ 840 +I ++ ++ + RKA Q+ +K S Y + + VN+ +L + + ++ Sbjct: 2039 TIEFLQSQVEKEQYIFRKASQVYEREVSARKIQSAYRLFK---VNQ--ILYRYKQQIDN- 2092 Query: 841 LLEIEHENKE-LQKKNQIL--LEENQNLQISLSDMQQHYNALVEKA---NRTDLAESEST 894 L +I ++ KE + + + L LE+ + S+ QQ+ E+ +L +E Sbjct: 2093 LRKINYDYKEKIDRLQEQLYDLEDEIEKEKSVISQQQNEQVFQERGFLQENINLLNTEFK 2152 Query: 895 KYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAI----RDKKVLNEKY 950 K + Q E+ + + +TL QK KE++ T +E+ +DK++L E Y Sbjct: 2153 KNEPQRGSRENQISSLQKSEKTL-KQKLKELDQSWKNQYTHLENKHLELQKDKQILTESY 2211 Query: 951 EKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINE 1010 E+ + + + +A L EY+N IE +N ++ + +I +V+ ++ Q E+ E Sbjct: 2212 EQTLAIIKKDKALLIEYQNQIE-INRRQDKAAR----IIQNYVKNRKLQQEQ--EKLQKE 2264 Query: 1011 INKLNALLKQKDEEI--IALNQKINNAQVSYMSMVSDY 1046 L+ + K K+ + Q + N + +++ ++ Sbjct: 2265 KEDLSKIFKLKNAQTGQYLFQQSLKNVNQIFTNLIQNF 2302 >UniRef50_A2EVM3 Cluster: Viral A-type inclusion protein, putative; n=2; Trichomonas vaginalis G3|Rep: Viral A-type inclusion protein, putative - Trichomonas vaginalis G3 Length = 2207 Score = 175 bits (427), Expect = 6e-42 Identities = 294/1508 (19%), Positives = 646/1508 (42%), Gaps = 125/1508 (8%) Query: 92 ESLANTLKQKEILMEKIKQY-KELSKR-SSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSN 149 E+L NT + E +K+K+ K ++ R + +L +T + + Sbjct: 467 ENLQNTPDKSEEFNQKLKELEKAINDRLKQNSETDAKNKQLQDAVDNKNRELETITVVQD 526 Query: 150 TIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXX 209 +E L+ ++ +++ ++ +L +K+NE I+ Sbjct: 527 NSEELQKQLNDIKDQIEKLKNNSNELTDKLNELKSNIDTDKGVLDSLNDNADVLNVQIEE 586 Query: 210 XXEDTKQQMTKMQENF--IAMEAEWKDEKQRLLKDIESK-DVRISSLEEA-NKLLEAARF 265 ++ ++ K+QE IA + E EK +++ +++ D I ++EE N+ + Sbjct: 587 KNQEYERLEDKIQELIADIATKTEKVGEKDAQVEEKKAQLDELIKAIEERKNQSEQNNEN 646 Query: 266 EISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELT 325 SL+H E ++ ++Q+ E + + +I+EK A + EL Sbjct: 647 NDSLQHQ--IDEKQRQLDELIKAIEERKNQSEQNKENNDSLQQQIDEKK----AQLDELN 700 Query: 326 KKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSP 385 K IE ++ + Q + N L+ + + ++ LI R K +S Sbjct: 701 KAIEERKNQSEQNNENNDSLQQQ----------IDEKQRQLDELIKAIEER----KNQSE 746 Query: 386 WSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISE--KDTXXXXXXXXXX 443 ++ ++++L Q D+K + E K I +++L ++ ++ + D Sbjct: 747 QNKENNDSLQQQIDEKQRQLEAIKN---IPDNSEELKNQLQILEKAFNDKMEQNAANNKQ 803 Query: 444 GKDTLIAQL-QLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLI 502 +D + ++ +LE+ ++ S + +D+NE + ++ +EL D++++++ I Sbjct: 804 LQDAIDSKKKELENTPEVQDNSE-ELKKQLDDINEQIEKRKNDNKELEDKLEELS--KAI 860 Query: 503 EKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQ-KTIDNFSKVSDSNKEIVRLT 561 + K A+E+ + N+E++ IK K K L ++ KT + K++D K+I Sbjct: 861 NEQKLADEETAKKNEELE----KQIKDKEAEKNSLVPVEDKTEELARKLADLEKQIAEQL 916 Query: 562 EELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLES 621 E+ + K +LE++ Q L + ++++ + E EN E L+ ++ L+S Sbjct: 917 EKQNETDGKNKDLEQQIKEKQEKLDE------LKNNFIEDTKEKENEIEELLQELNDLDS 970 Query: 622 QKFDLVQELHILQQKYDEVEDKL-ADIS---QLQSDQVCSEIKS-----VHLEEQID--A 670 + ++ ++ Q++Y+E +D + +DI+ QL D + +K V EE ID A Sbjct: 971 KINEIQDQISQFQEEYEEKKDHIVSDINTKDQLLQDLMEENLKQLKETPVVAEEPIDSEA 1030 Query: 671 LSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMS-- 728 L ++A +IE + ++ E+ E ++N N +L +LE M Sbjct: 1031 LDKINDQMADLIERINSGDIDPSDLVEK-ESQMEALINNAIVDNHGNKELVKQLEDMRNK 1089 Query: 729 -AEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAV 787 E+I + L + E+ + + ++E+ IE++E +LS+ + + ESI Sbjct: 1090 MGERIDDYLNEAEKEDLEEEEETIPEQNSVEEKQDTIEDLEQQLSQKQKDL----ESIEP 1145 Query: 788 MEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLA----------VLMDHDRVV 837 +E ++ ++ K +++ + +KQ E + D L +LA + D + Sbjct: 1146 VESKKEEIQNKLNEIEKEINDKQAKNEEIKNENDALEQQLAEKKKELDSIPTVEDKTSDL 1205 Query: 838 EKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQ 897 E QL +IE + E + KN+ + N+ + L++ QQ +++ EKA ESES + + Sbjct: 1206 ESQLKDIESQINEKRAKNEETEKMNKEFEDKLAEKQQELDSIEEKAEEQTTPESESKEQE 1265 Query: 898 TQ----LRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKN 953 + L +LES ++ + I K+ E L + + I S + DK ++ + Sbjct: 1266 KEESKDLSELESKIRDLLER----IAAGDKDPETL-VSVSEDILSTLNDKIATSDSDDDK 1320 Query: 954 IEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINK 1013 + Y + + N +E ++E+ E + V+ + PD E ++ Sbjct: 1321 LRY----QQASETINNAVEQYLASLEDAYNDEEEEPIQEVETRDIILPDEAANEGEEESQ 1376 Query: 1014 LNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLD 1073 + L+ K +E+ + ++ S D +K+ + +L + +S Q + Sbjct: 1377 QSEELETKTDELKSQIADVDREIAEQKSKNDDLMNKINELQQQLAEKQNVRDSLSAQTAE 1436 Query: 1074 SKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMI--ISSTIEPMSDDANNVDXX 1131 ++ ++ + E+ I +L+ + + +IP++E +S+ I+ + + + Sbjct: 1437 LEEQLSKIGHDLEEEKKAISDLQSKEAELK-SIPQSEDKSEELSARIDEIKSEIDQKKSE 1495 Query: 1132 XXXXXXXXXXLKVQEEE--EFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHD 1189 L+ Q E+ + + +++S+ L E+++ +KI ++ N E++ + Sbjct: 1496 NEAIESKNNELQKQLEDFKKLLDSIPTQEDKSSDLEKEIKDTQSKINDKKSKNEEISNKN 1555 Query: 1190 VVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVD--QRGFEIAELWKQHLAQRE 1247 +EQ+ QL+ +LE L T D L E++++ S D ++ E K+ Q E Sbjct: 1556 NELEEQLTQLRQELETLPTVEDKLSDLENEIKNTESQINDKNEKNEETDNKNKELEQQLE 1615 Query: 1248 ADFQKTEHELRVQ--LSAFESKYEQLLDSV--QSSTQEETNKIVTMEQVTSLQNKLQDKE 1303 + Q+ E V+ S E++ + + DS+ ++S EET+K E + +++K Q+ E Sbjct: 1616 SKKQELESIPTVEDKSSELENELKSVADSINDKNSKNEETDK-KNKELESQIESKKQELE 1674 Query: 1304 EHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQ 1363 + +++ + N+++ + I ++K + + EN K+ + Sbjct: 1675 S-IPVVEDNSDSLSNELKSVEESINNKK------SKNDETDKKNKELEHQIEN---KKQE 1724 Query: 1364 EQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEY 1423 +SI + +++ +L+ + + + K EL QLE K E+ E Sbjct: 1725 LESIPVVEDKSPELENELQSIESFINDKNEKNEETDNKNKELEQQLESKKQEL-----ES 1779 Query: 1424 TITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIE 1483 T+ ++ E EN ++ E+ I+D K ++ ++ E + QK E+E Sbjct: 1780 IPTVEDKSSELEN---EIQSAEESIKD-KISKNEDIDNKNKELEE-----KVAQKREELE 1830 Query: 1484 RVKLIEELNVKITESVSLNKQVAELNKALEEEV-AKTNEMQTALENQEIEIVTLNDEITN 1542 + E + ++ E ++ A + + ++ N++ L ++ + N Sbjct: 1831 SIPTAESKSAEVAEPSQEEQEQASTTVSSPSSIKSELNDIADLLSKGDLSLEEFNSRAEK 1890 Query: 1543 LQNMVRAS 1550 L + + AS Sbjct: 1891 LISQLDAS 1898 Score = 175 bits (426), Expect = 8e-42 Identities = 295/1421 (20%), Positives = 611/1421 (42%), Gaps = 147/1421 (10%) Query: 175 LQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKD 234 LQ++I+EK ++ NKA + ++ ++ E A+E + Sbjct: 685 LQQQIDEKKAQLDELNKAIEERKNQSEQNNENNDSLQQQIDEKQRQLDELIKAIE----E 740 Query: 235 EKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXX 294 K + ++ E+ D ++E + LEA + I +L +L+ Sbjct: 741 RKNQSEQNKENNDSLQQQIDEKQRQLEAIK-NIPDNSEELKNQLQILEKAFNDKMEQNAA 799 Query: 295 LAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGT 354 KQ + +K E+E ++ N EL K+++ + + + NKELE+KL + Sbjct: 800 NNKQLQDAIDSKKKELENTPEVQ-DNSEELKKQLDDINEQIEKRKNDNKELEDKLEEL-- 856 Query: 355 ESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVI 414 SKA++ + + TA K + E Q DK+ KN + +E Sbjct: 857 -SKAINE---------QKLADEETAKK--------NEELEKQIKDKEAEKNSLVPVEDKT 898 Query: 415 QSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTED 474 + L + L D E I+E+ GK+ + Q E Q+ ++ + E Sbjct: 899 EELARKLADLEKQIAEQ----LEKQNETDGKNKDLEQQIKEKQEKLDELKNNFIEDTKEK 954 Query: 475 VNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEI--DAANKNMIKVKSN 532 NEI E+L QELND D + ++ +++ +E+ + D I D K+ + ++ Sbjct: 955 ENEI----EELLQELND--LDSKINEIQDQISQFQEEYEEKKDHIVSDINTKDQL-LQDL 1007 Query: 533 HKLKLKQMQKTIDNFSKVSDS------NKEIVRLTEELHHLSQKVAELEEEKGNLQLHLV 586 + LKQ+++T + DS N ++ L E ++ ++L E++ ++ + Sbjct: 1008 MEENLKQLKETPVVAEEPIDSEALDKINDQMADLIERINSGDIDPSDLVEKESQMEALIN 1067 Query: 587 DYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDL------VQELHILQQKYDEV 640 + ++ K++ +M N R+ L E++K DL + E + +++K D + Sbjct: 1068 NAIVDNHGNKELVKQLEDMRNKMGERIDDY-LNEAEKEDLEEEEETIPEQNSVEEKQDTI 1126 Query: 641 EDKLADISQLQSD-----QVCSEIKSVH-----LEEQIDALSASKKELA----LVIENLK 686 ED +SQ Q D V S+ + + +E++I+ A +E+ + + L Sbjct: 1127 EDLEQQLSQKQKDLESIEPVESKKEEIQNKLNEIEKEINDKQAKNEEIKNENDALEQQLA 1186 Query: 687 LDKEQLYG--TIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAE---KISELLAKINH 741 K++L T++D +D E + +++ I E ++ EKM+ E K++E +++ Sbjct: 1187 EKKKELDSIPTVEDKTSDLESQLKDIESQINEKRAKNEETEKMNKEFEDKLAEKQQELDS 1246 Query: 742 -EEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKAD 800 EE+++ QT ++K QE++ +LS+ +S+I L E IA + +L ++ Sbjct: 1247 IEEKAEEQTTPESESKEQEKEE-----SKDLSELESKIRDLLERIAAGDKDPETLVSVSE 1301 Query: 801 QLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLE 860 + S L +K A S+ +D+ + + VE+ L +E + +++ ++ Sbjct: 1302 DILSTLNDKI-ATSD---SDDDKLRYQQASETINNAVEQYLASLEDAYNDEEEEP---IQ 1354 Query: 861 ENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQ 920 E + I L D E AN + +S + +T+ +L+S + + E I + Sbjct: 1355 EVETRDIILPD---------EAANEGEEESQQSEELETKTDELKSQIADVDRE----IAE 1401 Query: 921 KKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEE 980 +K + +DL + N +++ + +K+ + + +LE QL + +++E + + Sbjct: 1402 QKSKNDDLMNKIN-ELQQQLAEKQNVRDSLSAQ---TAELEEQLSKIGHDLEEEKKAISD 1457 Query: 981 LNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYM 1040 L EL K QS D +E+ I+++ + + QK E A+ K N Q Sbjct: 1458 LQSKEAEL------KSIPQSEDKSEELSARIDEIKSEIDQKKSENEAIESKNNELQ---- 1507 Query: 1041 SMVSDYESKLAQFTT---KLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELK- 1096 + D++ L T K ++E+E++ ++ D K NEE+ E ++Q+ +L+ Sbjct: 1508 KQLEDFKKLLDSIPTQEDKSSDLEKEIKDTQSKINDKKSKNEEISNKNNELEEQLTQLRQ 1567 Query: 1097 --ETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQER 1154 ET T E + E I +T ++D + L+ +++E ++ Sbjct: 1568 ELETLPTVEDKLSDLENEI-KNTESQINDKNEKNEETDNKNKELEQQLESKKQE--LESI 1624 Query: 1155 SVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLL 1214 ++++S++L EL+ I + N E + + QI K +LE + DN Sbjct: 1625 PTVEDKSSELENELKSVADSINDKNSKNEETDKKNKELESQIESKKQELESIPVVEDNSD 1684 Query: 1215 STVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQL--- 1271 S EL+S + +++ + + E K++ + E + + EL + E K +L Sbjct: 1685 SLSNELKS-VEESINNKKSKNDETDKKN-KELEHQIENKKQELE-SIPVVEDKSPELENE 1741 Query: 1272 LDSVQSSTQEETNKIV-TMEQVTSLQNKLQDKEEHLRNL---QEKYADVINQIEILRSEI 1327 L S++S ++ K T + L+ +L+ K++ L ++ ++K +++ N+I+ I Sbjct: 1742 LQSIESFINDKNEKNEETDNKNKELEQQLESKKQELESIPTVEDKSSELENEIQSAEESI 1801 Query: 1328 EDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXX 1387 +D K++ R E +S + +S + E + + ++ + Sbjct: 1802 KD-KISKNEDIDNKNKELEEKVAQKREELESIPTAESKSA-EVAEPSQEEQEQASTTVSS 1859 Query: 1388 XXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKR 1447 +ND + + LE +S + + ++ +D + +L+E ++ Sbjct: 1860 PSSIKSELNDIADLLSKGDLSLEEFNSRAEKLISQLDASIVNSDDP--TTKSELIEAHEQ 1917 Query: 1448 IEDLTYEKESELAILRLKMHENANHY-ETMQKESEIERVKLIEELNVKI--TESVSLNKQ 1504 + D+ E +H A+ E ++E + ++ ++IEE K +ES L++ Sbjct: 1918 LNDIVEEY----------LHNYASAAAEEDEQEQDNDKEEIIEEQEQKQEPSESKDLSEL 1967 Query: 1505 VAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQN 1545 ++ LE + + +T + E + TLND+I N N Sbjct: 1968 EQQIRDLLEHLASGDEDPETLVSVSEDILSTLNDKIANSDN 2008 Score = 155 bits (377), Expect = 7e-36 Identities = 238/1238 (19%), Positives = 524/1238 (42%), Gaps = 100/1238 (8%) Query: 414 IQSLNKDLVDKEYVISEK-DTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNT 472 I L K+L + E + EK D T I + E + G S+ Sbjct: 376 IDELKKELAETEKKVQEKRDALDPTYAAMVYALKTAIEAKEQELENLQNGESV------E 429 Query: 473 EDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSN 532 E ++A V++Q++++ N +++++ + + ++ E + D+ + N+ + +++ Sbjct: 430 ELKKKLADVEKQIEEQKNKSSDNISLEHQLAEKQAELENLQNTPDKSEEFNQKLKELEKA 489 Query: 533 HKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGR 592 +LKQ +T ++ D+ R E + + EL+++ +++ + + Sbjct: 490 INDRLKQNSETDAKNKQLQDAVDNKNRELETITVVQDNSEELQKQLNDIKDQIEKLKNN- 548 Query: 593 MIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQS 652 +++ K+ E+++ +T + L L ++ Q+Y+ +EDK I +L + Sbjct: 549 --SNELTDKLNELKSNIDTDKGVLDSLNDNADVLNVQIEEKNQEYERLEDK---IQELIA 603 Query: 653 DQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQN 712 D K + Q++ A EL IE K EQ L++ ++ +L Sbjct: 604 DIATKTEKVGEKDAQVEEKKAQLDELIKAIEERKNQSEQNNENNDSLQHQIDEKQRQLDE 663 Query: 713 YIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELS 772 I+ + ++ E+ + E L +I+ ++ + I+ + + + EN +S Sbjct: 664 LIKAIEERKNQSEQ-NKENNDSLQQQIDEKKAQLDELNKAIEERKNQSEQNNENNDSLQQ 722 Query: 773 KYKSRICRLEESIAVMEDRRYSLERKA---DQLGSYLQEKQK---AYSEYTIQEDELVNR 826 + + +L+E I +E+R+ E+ D L + EKQ+ A +EL N+ Sbjct: 723 QIDEKQRQLDELIKAIEERKNQSEQNKENNDSLQQQIDEKQRQLEAIKNIPDNSEELKNQ 782 Query: 827 LAVL-------MDHDRVVEKQLLE-IEHENKELQKKNQILLEENQNLQISLSDMQQHYNA 878 L +L M+ + KQL + I+ + KEL+ ++ + ++ L+ L D+ N Sbjct: 783 LQILEKAFNDKMEQNAANNKQLQDAIDSKKKELENTPEV-QDNSEELKKQLDDI----NE 837 Query: 879 LVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIES 938 +EK + D E E K + +L + K E + +K+I+D E E N+ + Sbjct: 838 QIEK-RKNDNKELED-KLE-ELSKAINEQKLADEETAKKNEELEKQIKDKEAEKNSLV-- 892 Query: 939 AIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDK---HVQK 995 + DK E K + Q+ QL E +N + N ++E+ K E +D+ + + Sbjct: 893 PVEDK--TEELARKLADLEKQIAEQL-EKQNETDGKNKDLEQQIKEKQEKLDELKNNFIE 949 Query: 996 QQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTT 1055 + + E+ + E+N L++ + + ++I ++ + +S ++ + L Sbjct: 950 DTKEKENEIEELLQELNDLDSKINEIQDQISQFQEEYEEKKDHIVSDINTKDQLLQDLME 1009 Query: 1056 KLENMEEEMQRVSKQLLDSK---QHNEELQIL---VREQDDQIKEL--KETKLTFEMNIP 1107 + +E V+++ +DS+ + N+++ L + D +L KE+++ +N Sbjct: 1010 ENLKQLKETPVVAEEPIDSEALDKINDQMADLIERINSGDIDPSDLVEKESQMEALINNA 1069 Query: 1108 KTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTE 1167 + ++ + D N + ++EEEE I E++ ++E+ + Sbjct: 1070 IVDNHGNKELVKQLEDMRNKMGERIDDYLNEAEKEDLEEEEETIPEQNSVEEKQDTIEDL 1129 Query: 1168 LQECYTKIIQLETLN-TELTGHDVVN-----QEQINQLKSKLEQLNTENDNLLSTVAELR 1221 Q+ K LE++ E ++ N +++IN ++K E++ END L +AE + Sbjct: 1130 EQQLSQKQKDLESIEPVESKKEEIQNKLNEIEKEINDKQAKNEEIKNENDALEQQLAEKK 1189 Query: 1222 SSISS--AVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKY---EQLLDSVQ 1276 + S V+ + ++ K +Q K E E FE K +Q LDS++ Sbjct: 1190 KELDSIPTVEDKTSDLESQLKDIESQINEKRAKNE-ETEKMNKEFEDKLAEKQQELDSIE 1248 Query: 1277 SSTQEETN-KIVTMEQVTSLQNKLQDKEEHLRNLQEKYA--------------DVINQI- 1320 +E+T + + EQ L + E +R+L E+ A D+++ + Sbjct: 1249 EKAEEQTTPESESKEQEKEESKDLSELESKIRDLLERIAAGDKDPETLVSVSEDILSTLN 1308 Query: 1321 -EILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLR-----TENQSYKQMQEQSILNINE-- 1372 +I S+ +D+K+ + L E + ++++ + I+ +E Sbjct: 1309 DKIATSDSDDDKLRYQQASETINNAVEQYLASLEDAYNDEEEEPIQEVETRDIILPDEAA 1368 Query: 1373 -ENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRN 1431 E + + S ++ D + ++ E + K+ ++ K +E L ++ Sbjct: 1369 NEGEEESQQSEELETKTDELKSQIADVDREIAE----QKSKNDDLMNKINELQQQLAEKQ 1424 Query: 1432 DEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKL-IEE 1490 + +++ Q E E+++ + ++ E E + + A Q E + E + I+E Sbjct: 1425 NVRDSLSAQTAELEEQLSKIGHDLEEEKKAISDLQSKEAELKSIPQSEDKSEELSARIDE 1484 Query: 1491 LNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRAS 1550 + +I + S N+ + N L++++ ++ ++ QE + L EI + Q+ + Sbjct: 1485 IKSEIDQKKSENEAIESKNNELQKQLEDFKKLLDSIPTQEDKSSDLEKEIKDTQSKINDK 1544 Query: 1551 SSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAE 1588 SK ++ S+ +EQL T ++ L+ +P E Sbjct: 1545 KSKNEE----ISNKNNELEEQL--TQLRQELETLPTVE 1576 Score = 153 bits (370), Expect = 5e-35 Identities = 264/1462 (18%), Positives = 618/1462 (42%), Gaps = 131/1462 (8%) Query: 212 EDTKQQMTKMQENFIAME---AEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEIS 268 ED K + ++ + ++ E ++ ++E++ DI + +++SL+ N L E+S Sbjct: 18 EDNKSAIEDLRRDVVSEEDLHSQLENEQEASFADISELNAKLASLQTDNSFLP----EVS 73 Query: 269 LEHSKLAQELEQXXXXXXXXXXXXXXLAK--QSIEPSCEEKTE-------IEEKGSLEIA 319 EHSKL ++ +K Q++E E K + +E+K + Sbjct: 74 DEHSKLLADISAIESSIADKRSRNEETSKLNQALEAELESKKKQLSFLPTVEDKSASLEN 133 Query: 320 NMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISR-KSGRNT 378 + ++ +I N + + NKELE +LA + + ++ S + L S+ N Sbjct: 134 EIKKVDSEINTKNSQNAETEKKNKELEEQLAKIQQDLDSIPSTNDNSHFLQSQIDQIINE 193 Query: 379 ASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXX 438 + + + E +D DK+ N N + + + + D ++ + ++ + Sbjct: 194 HNSHNDEPEKANKEIQQKDADKQQN-NISTESDESSKQFSSDDLNLDGLLDDIAGGYRSD 252 Query: 439 XXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKV----------------- 481 + + Q + +H + + + + D ++A V Sbjct: 253 SSLIESNNEIEDDQQSVNDEHEKMNHVSELNKDLHDSLQLAPVIGEPSFVEFADSIVGRI 312 Query: 482 -QEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQM 540 ++ +E +E ++V K + K + T +D+ KS+ K K+ Sbjct: 313 DKDHEVEEEEEEEEEVEEKQAADVQKLKSHRDTDSDDDGAPLGNQTSPTKSSDKSSPKER 372 Query: 541 QKTIDNFSK-VSDSNKEIVRLTEELH-HLSQKVAELEEEKGNLQLHLVDYDSGRMIESDV 598 ID K ++++ K++ + L + V L+ + L + +G +E ++ Sbjct: 373 SDNIDELKKELAETEKKVQEKRDALDPTYAAMVYALKTAIEAKEQELENLQNGESVE-EL 431 Query: 599 YKKMIEMENLAETRLKAIS---LLESQKFDLVQELHILQ---QKYDEVEDKLADISQLQS 652 KK+ ++E E + S LE Q + EL LQ K +E KL ++ + + Sbjct: 432 KKKLADVEKQIEEQKNKSSDNISLEHQLAEKQAELENLQNTPDKSEEFNQKLKELEKAIN 491 Query: 653 DQVC----SEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKD----LENDKE 704 D++ ++ K+ L++ +D + + + +V +N + ++QL IKD L+N+ Sbjct: 492 DRLKQNSETDAKNKQLQDAVDNKNRELETITVVQDNSEELQKQL-NDIKDQIEKLKNNSN 550 Query: 705 DIMNKLQNYIQENMDLTDK--LEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDL 762 ++ +KL N ++ N+D TDK L+ ++ + L +I + Q + + I I + Sbjct: 551 ELTDKL-NELKSNID-TDKGVLDSLN-DNADVLNVQIEEKNQEYERLEDKIQELIADIAT 607 Query: 763 YIENIESELSKYKSRICRLEESIAVMEDRRYSLER---KADQLGSYLQEKQKAYSEYTIQ 819 E + + ++ + + +L+E I +E+R+ E+ D L + EKQ+ E Sbjct: 608 KTEKVGEKDAQVEEKKAQLDELIKAIEERKNQSEQNNENNDSLQHQIDEKQRQLDELIKA 667 Query: 820 EDELVNRLAVLMDHDRVVEKQL----LEIEHENKEL-QKKNQILL--EENQNLQISLSDM 872 +E N+ +++ +++Q+ +++ NK + ++KNQ E N +LQ + + Sbjct: 668 IEERKNQSEQNKENNDSLQQQIDEKKAQLDELNKAIEERKNQSEQNNENNDSLQQQIDEK 727 Query: 873 QQHYNALV----EKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDL 928 Q+ + L+ E+ N+++ + + Q Q+ + + L+ I + + K +++ L Sbjct: 728 QRQLDELIKAIEERKNQSEQNKENNDSLQQQIDEKQRQLEAIKNIPDN-SEELKNQLQIL 786 Query: 929 EIEFNTQIESAIRDKKVLNEKYE---KNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMN 985 E FN ++E + K L + + K +E +++ +E K ++++N +E+ N Sbjct: 787 EKAFNDKMEQNAANNKQLQDAIDSKKKELENTPEVQDNSEELKKQLDDINEQIEKRKNDN 846 Query: 986 LELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSD 1045 EL DK + + INE + +K+EE L ++I + + S+V Sbjct: 847 KELEDKLEELSKA---------INEQKLADEETAKKNEE---LEKQIKDKEAEKNSLV-P 893 Query: 1046 YESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMN 1105 E K + KL ++E+++ ++ ++ N++L+ ++E+ +++ ELK + + Sbjct: 894 VEDKTEELARKLADLEKQIAEQLEKQNETDGKNKDLEQQIKEKQEKLDELKNNFIE-DTK 952 Query: 1106 IPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLN 1165 + E + + + N + K + + +LQ+ + Sbjct: 953 EKENEIEELLQELNDLDSKINEIQDQISQFQEEYEEKKDHIVSDINTKDQLLQDLMEENL 1012 Query: 1166 TELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSIS 1225 +L+E T ++ E +++E D +N +Q+ L ++ + + +L+ +++ + I+ Sbjct: 1013 KQLKE--TPVVAEEPIDSEAL--DKIN-DQMADLIERINSGDIDPSDLVEKESQMEALIN 1067 Query: 1226 SA-VDQRG------------FEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLL 1272 +A VD G ++ E +L + E + + E E + ++ E K + + Sbjct: 1068 NAIVDNHGNKELVKQLEDMRNKMGERIDDYLNEAEKEDLEEEEETIPEQNSVEEKQDTIE 1127 Query: 1273 DSVQSSTQEETNKIVTMEQVTS----LQNKLQDKEEHLRNLQEKYADVINQIEILRSEIE 1328 D Q +Q++ + + ++E V S +QNKL + E+ + + Q K ++ N+ + L ++ Sbjct: 1128 DLEQQLSQKQKD-LESIEPVESKKEEIQNKLNEIEKEINDKQAKNEEIKNENDALEQQLA 1186 Query: 1329 DEKVAFXX--XXXXXXXXXXXXXXDLRTE-NQSYKQMQEQSILNINEENAQLKKSSXXXX 1385 ++K D+ ++ N+ + +E +N E+ +K Sbjct: 1187 EKKKELDSIPTVEDKTSDLESQLKDIESQINEKRAKNEETEKMNKEFEDKLAEKQQELDS 1246 Query: 1386 XXXXXXXXRVNDAEAKVLELTHQLELKDSE---------IYQKTHEYTITLTQRNDEFEN 1436 ++E+K E +L + E I + ++ D Sbjct: 1247 IEEKAEEQTTPESESKEQEKEESKDLSELESKIRDLLERIAAGDKDPETLVSVSEDILST 1306 Query: 1437 VRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKIT 1496 + ++ + + L Y++ SE + + + E + E E ++ +E ++ + Sbjct: 1307 LNDKIATSDSDDDKLRYQQASE--TINNAVEQYLASLEDAYNDEEEEPIQEVETRDIILP 1364 Query: 1497 ESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQK 1556 + + + E ++ EE KT+E+++ + + + EI + +L N + ++ + Sbjct: 1365 DEAA--NEGEEESQQSEELETKTDELKSQIADVDREIAEQKSKNDDLMNKINELQQQLAE 1422 Query: 1557 HVSFASDTKQGRDEQLDNTMNK 1578 + D+ + +L+ ++K Sbjct: 1423 KQN-VRDSLSAQTAELEEQLSK 1443 Score = 101 bits (243), Expect = 1e-19 Identities = 180/915 (19%), Positives = 390/915 (42%), Gaps = 94/915 (10%) Query: 682 IENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINH 741 ++NLKL+ L I+D ++ ED+ + + + L ++ E A+ ISEL AK+ Sbjct: 3 LDNLKLENSALQSCIEDNKSAIEDLRRDVVSEEDLHSQLENEQEASFAD-ISELNAKL-- 59 Query: 742 EEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQ 801 A +Q + ++ + E SK + I +E SIA R + Sbjct: 60 -------------ASLQTDNSFLPEVSDEHSKLLADISAIESSIADKRSRNEETSKLNQA 106 Query: 802 LGSYLQEKQKAYSEYTIQEDE---LVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQIL 858 L + L+ K+K S ED+ L N + + Q E E +NKEL+++ + Sbjct: 107 LEAELESKKKQLSFLPTVEDKSASLENEIKKVDSEINTKNSQNAETEKKNKELEEQLAKI 166 Query: 859 LEE-------NQNLQISLSDMQQ------HYNALVEKANRTDLAESESTKYQTQL-RDLE 904 ++ N N S + Q +N EKAN+ ++ + ++ K Q + + + Sbjct: 167 QQDLDSIPSTNDNSHFLQSQIDQIINEHNSHNDEPEKANK-EIQQKDADKQQNNISTESD 225 Query: 905 SNLKRITHEHQTL-----IVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQ 959 + K+ + + L + + IE N +IE D++ +N+++EK + +V++ Sbjct: 226 ESSKQFSSDDLNLDGLLDDIAGGYRSDSSLIESNNEIED---DQQSVNDEHEK-MNHVSE 281 Query: 960 LEAQLQEYKNNIENL-NMNVEELNKMNLELIDK--HVQKQQTQSPDYTEQYINEINKLNA 1016 L L + + + E + IDK V++++ + + E+ ++ KL + Sbjct: 282 LNKDLHDSLQLAPVIGEPSFVEFADSIVGRIDKDHEVEEEEEEEEEVEEKQAADVQKLKS 341 Query: 1017 LL-KQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQL---- 1071 D++ L + + + S S + + + +L E+++Q L Sbjct: 342 HRDTDSDDDGAPLGNQTSPTKSSDKSSPKERSDNIDELKKELAETEKKVQEKRDALDPTY 401 Query: 1072 ------LDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMI---ISSTIEPMS 1122 L + +E ++ + + ++ELK+ E I + + IS + Sbjct: 402 AAMVYALKTAIEAKEQELENLQNGESVEELKKKLADVEKQIEEQKNKSSDNISLEHQLAE 461 Query: 1123 DDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECY-TKIIQLETL 1181 A + K++E E+ I +R ++ N +LQ+ K +LET+ Sbjct: 462 KQAELENLQNTPDKSEEFNQKLKELEKAINDRLKQNSETDAKNKQLQDAVDNKNRELETI 521 Query: 1182 NTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISS--AVDQRGFEIAELW 1239 T + + Q+Q+N +K ++E+L ++ L + EL+S+I + V + A++ Sbjct: 522 -TVVQDNSEELQKQLNDIKDQIEKLKNNSNELTDKLNELKSNIDTDKGVLDSLNDNADVL 580 Query: 1240 KQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKL 1299 + ++ ++++ E +++ ++ +K E++ + +++ ++ + +N+ Sbjct: 581 NVQIEEKNQEYERLEDKIQELIADIATKTEKVGEKDAQVEEKKAQLDELIKAIEERKNQS 640 Query: 1300 QDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSY 1359 + E+ +LQ + + Q++ L IE+ K + N S Sbjct: 641 EQNNENNDSLQHQIDEKQRQLDELIKAIEERK---------------NQSEQNKENNDSL 685 Query: 1360 KQMQEQSILNINEENAQL---KKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEI 1416 +Q ++ ++E N + K S ++++ + ++ EL +E + ++ Sbjct: 686 QQQIDEKKAQLDELNKAIEERKNQSEQNNENNDSLQQQIDEKQRQLDELIKAIEERKNQ- 744 Query: 1417 YQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRL----KMHENANH 1472 ++ E +L Q+ DE +Q+ +E K I D + E +++L IL KM +NA + Sbjct: 745 SEQNKENNDSLQQQIDE----KQRQLEAIKNIPDNSEELKNQLQILEKAFNDKMEQNAAN 800 Query: 1473 YETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALE--NQE 1530 + +Q + ++ +L V+ S L KQ+ ++N+ +E+ E++ LE ++ Sbjct: 801 NKQLQDAIDSKKKELENTPEVQ-DNSEELKKQLDDINEQIEKRKNDNKELEDKLEELSKA 859 Query: 1531 IEIVTLNDEITNLQN 1545 I L DE T +N Sbjct: 860 INEQKLADEETAKKN 874 Score = 66.9 bits (156), Expect = 4e-09 Identities = 109/712 (15%), Positives = 297/712 (41%), Gaps = 53/712 (7%) Query: 897 QTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEY 956 ++ + DL ++ H L +++ D+ E N ++ S D L E +++ Sbjct: 21 KSAIEDLRRDVVSEEDLHSQLENEQEASFADIS-ELNAKLASLQTDNSFLPEVSDEH--- 76 Query: 957 VTQLEAQLQEYKNNIENLNMNVEELNKMN--LELIDKHVQKQQTQSP---DYTEQYINEI 1011 ++L A + +++I + EE +K+N LE + +KQ + P D + NEI Sbjct: 77 -SKLLADISAIESSIADKRSRNEETSKLNQALEAELESKKKQLSFLPTVEDKSASLENEI 135 Query: 1012 NKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQL 1071 K+++ + K+ + +K + + D +S + +N ++ + + Sbjct: 136 KKVDSEINTKNSQNAETEKKNKELEEQLAKIQQDLDS----IPSTNDNSHFLQSQIDQII 191 Query: 1072 LDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXX 1131 + HN+E + +E + + ++ ++ E + + ++ + DD Sbjct: 192 NEHNSHNDEPEKANKEIQQKDADKQQNNISTESDESSKQFSSDDLNLDGLLDDI--AGGY 249 Query: 1132 XXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQL-ETLNTELTGHDV 1190 +++++++ + + ++LN +L + + E E V Sbjct: 250 RSDSSLIESNNEIEDDQQSVNDEHEKMNHVSELNKDLHDSLQLAPVIGEPSFVEFADSIV 309 Query: 1191 VNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIA-ELWKQHLAQREAD 1249 ++ ++++ + E+ + + V +L+S + D G + + + + + Sbjct: 310 GRIDKDHEVEEEEEEEEEVEEKQAADVQKLKSHRDTDSDDDGAPLGNQTSPTKSSDKSSP 369 Query: 1250 FQKTEH--ELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLR 1307 +++++ EL+ +L+ E K ++ D++ + V +L+ ++ KE+ L Sbjct: 370 KERSDNIDELKKELAETEKKVQEKRDALDPTYAA---------MVYALKTAIEAKEQELE 420 Query: 1308 NLQ--EKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQ-SYKQMQE 1364 NLQ E ++ ++ + +IE++K ++ E+Q + KQ + Sbjct: 421 NLQNGESVEELKKKLADVEKQIEEQK--------------NKSSDNISLEHQLAEKQAEL 466 Query: 1365 QSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSE------IYQ 1418 +++ N +++ + + + ++ +AK +L ++ K+ E + Sbjct: 467 ENLQNTPDKSEEFNQKLKELEKAINDRLKQNSETDAKNKQLQDAVDNKNRELETITVVQD 526 Query: 1419 KTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQK 1478 + E L D+ E ++ E ++ +L +++ +L +++NA+ + Sbjct: 527 NSEELQKQLNDIKDQIEKLKNNSNELTDKLNELKSNIDTDKGVLD-SLNDNADVLNVQIE 585 Query: 1479 ESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLND 1538 E E +L +++ I + + ++V E + +EE+ A+ +E+ A+E ++ + N+ Sbjct: 586 EKNQEYERLEDKIQELIADIATKTEKVGEKDAQVEEKKAQLDELIKAIEERKNQSEQNNE 645 Query: 1539 EITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELD 1590 +LQ+ + ++ + + + K ++ +N + + +A+LD Sbjct: 646 NNDSLQHQIDEKQRQLDELIKAIEERKNQSEQNKENNDSLQQQIDEKKAQLD 697 >UniRef50_A2ERL6 Cluster: Viral A-type inclusion protein, putative; n=1; Trichomonas vaginalis G3|Rep: Viral A-type inclusion protein, putative - Trichomonas vaginalis G3 Length = 2832 Score = 175 bits (426), Expect = 8e-42 Identities = 284/1454 (19%), Positives = 615/1454 (42%), Gaps = 109/1454 (7%) Query: 168 METTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIA 227 + T I +LQ+++ I+AK K + Q+ + + A Sbjct: 403 LNTKISNLQKELENAKDTIDAKQKKISTMYERMKAPLLEQNQKIN----QLESLIDTLNA 458 Query: 228 MEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXX 287 + KD +LLKD RIS ++ N L+A ++ +K+ + ++ Sbjct: 459 KNGKQKDSI-KLLKD------RISQFQDNNSKLQAKIAKLEAT-AKIHENEKETLNSKID 510 Query: 288 XXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELEN 347 + + +++ + ++E +T+ T+K + + N R+ N EL Sbjct: 511 YLSKENNIKEDTVKKVQDANQSLKEYKETATKQITDNTQKFQEILDENQSYREKNAELSR 570 Query: 348 KLATMGTE-SKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNE 406 KL + ++ + K + K + A +K +L E + K+ KN+ Sbjct: 571 KLLESQKQIDDLINGFNDKDQQI---KGIKGEAGTVKQKIKELLDE------NSKL-KNK 620 Query: 407 IAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLI 466 I++L+ ++ N K+ + ++ +D L L+ + Sbjct: 621 ISELDQSLK--NSQTAQKQTTLKTQEQLKQNDSLQNILEDKNSELLSLKELNSTNENQIN 678 Query: 467 HVGT---NTEDVNEIAKVQEQLKQELNDEIKDVNVK-----DLIEKLKSAEEQITQLNDE 518 + T N + N+ KV Q E NDE+++ +K DLI++ + + Q+ +E Sbjct: 679 KLKTKLDNLQKENDELKVSLQKVTERNDELENTTIKSDKANDLIQENMTLKSQMKDAKNE 738 Query: 519 IDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVS-DSNKEIVRLTEELHHLSQKVAE-LEE 576 M +++ ++L LKQ Q+ ++ K + +N ++ ++ ++ V++ L + Sbjct: 739 NAKTMNEMKQIQLENEL-LKQNQQNLEKEIKENIQNNLDLQNKLNKIEWDNKIVSDKLAK 797 Query: 577 EKGNLQLHLVDYDSGRMIESDVYKKMIEMENLA-ETRLKAISLLESQKFDLVQELHI-LQ 634 EK +L+L + + + ++ ++K+ E ENLA +L ++ L D +Q + LQ Sbjct: 798 EKSSLELQNENLQNQNKLLNENHQKVTE-ENLAISQKLNDLNNLNKMCQDELQSTSLTLQ 856 Query: 635 QKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYG 694 +K E+ED + L+ + + + + +E +I L K + + DK+ Sbjct: 857 RKEKELEDLKQKMENLEKEFYDVKTEKMSMENKIFDLEKESKNQNDNMNKIIEDKDL--- 913 Query: 695 TIKDLENDKEDIMNK---LQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQF 751 IKDL E + + LQN +EN +L + + + E +EL KI+ + + + + Sbjct: 914 QIKDLRTKNEKLTEENSNLQNKEKENKNLQSRNQIVEKEN-TELSQKISSQNERINELEN 972 Query: 752 GIDAKIQERDLYIENIESELSKYKSR-ICRLEESIAVMEDRRYSLERKADQLGSYLQEKQ 810 + +Q + L ++ ++++ ++ + S+ M + L+RK +++ + L EK Sbjct: 973 AVST-LQNQILENDDKSQKVTEQTAKDLIAANSSLKQMTYQNELLQRKQNEMENDLDEKS 1031 Query: 811 KAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLS 870 + + D+L + L + +R + +I EN ++ + + + +EN++ + L Sbjct: 1032 SRIKDLEDENDDLQKEILELQNENRKISSNYEKISKENNRIEMEMKQIKDENESNKQKLV 1091 Query: 871 DMQQHYNALVEKANRTDLAESESTKYQTQLRD---LESNLK-------RITHEHQTLIVQ 920 D + + EK N + A+S+ +K +D L SN+K ++ +E+ L + Sbjct: 1092 DNTKKHEE--EKMNLINNAKSDKSKIDGLTKDISMLNSNIKLLQDENSKLDNENSQLENE 1149 Query: 921 KKKEIEDLE-----IEFNTQI-ESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENL 974 KK EDL+ I N + ++ + K L +K E + Q++ +Q+ N +L Sbjct: 1150 IKKLTEDLQKQNEKINDNQNLLQNVTNENKKLKDKNELLFKENEQIKNLMQDKINENNSL 1209 Query: 975 N-MNVEELNKMNLE-LIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKI 1032 +E N +N E L ++ + + + ++ + + K NA L Q ++ + N ++ Sbjct: 1210 KEKQIEMENDLNTEKLNNERLVGRLKEIENHNKSKKDNTAKENAKLTQNNKALANENFEL 1269 Query: 1033 NNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNE----ELQIL---- 1084 + +SD ++K + ++++ E+E+Q+ + + K NE E+Q L Sbjct: 1270 KQKVANLDQELSDVKNKFDKMSSQISESEKEVQQNAAEFRQIKAKNESLNKEVQFLNDLV 1329 Query: 1085 --VREQDDQIKELKET-KLTFEMNIPKTEGMI--ISSTIEPMSDDANNVDXXXXXXXXXX 1139 +++Q+D ++ KE TF +I + I + E + + + Sbjct: 1330 TNLKQQNDDLRNKKEELNTTFSEDIDNISNELREIKTQNEFLRKENEEMKNQSQLTKADN 1389 Query: 1140 XXLKVQEE-EEFIQERSVLQ-EQSAKLNTELQECYTKIIQ-LETLNTELTGHDVVNQEQI 1196 LK + + ++ I +S+++ + KLN ++ + KI L+ L E +D E I Sbjct: 1390 DKLKEENQNQKEINTKSLMKINELEKLNKQINDEMAKIQNNLQNLTQEKEENDSKQDEII 1449 Query: 1197 NQLKSKLEQLNTENDNLLSTVAELRSSIS------SAVDQRGFEIAELWKQHLAQREADF 1250 + + + E L +EN N + + L V + ++AE K E Sbjct: 1450 KEYEQENETLRSENQNFETKIKVLEKENKLNVFSLQKVTKEKEDLAEKLKNQKEVNET-L 1508 Query: 1251 QKTEHELRVQ---LSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLR 1307 +K + +L + L E K +Q+L S + +++ N + ++ L N+ D ++ + Sbjct: 1509 EKAKEDLETENNNLKLNEDKIKQIL-SENENLKQKLNDL--QKENNDLVNESNDIKQKQK 1565 Query: 1308 NLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSI 1367 E + NQ E L +++ D + F + + + + ++ Sbjct: 1566 EEMESSKENQNQKEKLENDLNDLQKNFDELQKSYSDLLEKYKAENDQKESQFNNVNS-NL 1624 Query: 1368 LNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTH---QLELKDSEIYQKTHEYT 1424 N +N L++ +++ + + EL + +++++S + + Sbjct: 1625 KQSNYQNDLLQRKLKDLEEEMKNDKEKIDTLQNRNEELENLFGNMKIENSSALANSDK-- 1682 Query: 1425 ITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIER 1484 LT+ N+ ++ L + I E EL ++ + EN N YE + KE + Sbjct: 1683 --LTKENEALKSENLSLKQTNNEITTKNKELSIELEKIKQNLEENQNSYENVFKEKSDIK 1740 Query: 1485 VKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQ 1544 KL ++L + + + NK + + + LEE K N+ + +EN ++ L + L+ Sbjct: 1741 EKL-DQLIQETNDQKAANKNLLKEKETLEE-TQKQNQKE--IENLIQKVTKLKAKNDFLK 1796 Query: 1545 NMVRASSSKIQKHV 1558 + S SK+Q + Sbjct: 1797 ENITESKSKLQGEI 1810 Score = 175 bits (426), Expect = 8e-42 Identities = 288/1467 (19%), Positives = 636/1467 (43%), Gaps = 115/1467 (7%) Query: 148 SNTIKEKDNALSVLQVKMKIMETTILDLQ-EKINEKDQI--IEAKNKATTXXXXXXXXXX 204 S T++ K+ L L+ KM+ +E D++ EK++ +++I +E ++K Sbjct: 852 SLTLQRKEKELEDLKQKMENLEKEFYDVKTEKMSMENKIFDLEKESKNQNDNMNKIIEDK 911 Query: 205 XXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISS-LEEANKLLEAA 263 +++T+ N E E K+ + R + +E ++ +S + N+ + Sbjct: 912 DLQIKDLRTKNEKLTEENSNLQNKEKENKNLQSRN-QIVEKENTELSQKISSQNERINEL 970 Query: 264 RFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTE 323 +S +++ + + A S++ + ++ K + ++ E Sbjct: 971 ENAVSTLQNQILEN-DDKSQKVTEQTAKDLIAANSSLKQMTYQNELLQRKQNEMENDLDE 1029 Query: 324 LTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMK 383 + +I+ LE N +++ EL+N+ + + + +S + + + + N ++K K Sbjct: 1030 KSSRIKDLEDENDDLQKEILELQNENRKISSNYEKISKENNRIEMEMKQIKDENESNKQK 1089 Query: 384 --SPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXX 441 + E +N + K +K++I L I LN ++ + + E Sbjct: 1090 LVDNTKKHEEEKMNLINNAKSDKSKIDGLTKDISMLNSNI---KLLQDENSKLDNENSQL 1146 Query: 442 XXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDL 501 L LQ ++++ + +L+ TN N+ K + +L + N++IK++ ++D Sbjct: 1147 ENEIKKLTEDLQKQNEKINDNQNLLQNVTNE---NKKLKDKNELLFKENEQIKNL-MQDK 1202 Query: 502 IEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLT 561 I + S +E+ ++ ++++ N ++ +LK+++ N SK ++ KE +LT Sbjct: 1203 INENNSLKEKQIEMENDLNTEKLNNERLVG----RLKEIEN--HNKSKKDNTAKENAKLT 1256 Query: 562 EELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLES 621 + L+ + EL+++ NL L SDV K +M + K + + Sbjct: 1257 QNNKALANENFELKQKVANLDQEL----------SDVKNKFDKMSSQISESEKEVQQNAA 1306 Query: 622 QKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVH--LEEQIDALSASKKELA 679 + + + L ++ + D + ++ Q Q+D + ++ + ++ E ID +S +E+ Sbjct: 1307 EFRQIKAKNESLNKEVQFLNDLVTNLKQ-QNDDLRNKKEELNTTFSEDIDNISNELREIK 1365 Query: 680 LVIENLKLDKEQL--YGTIKDLENDKEDIMNKLQNYIQ-ENMDLTDKLEKMSAEKISELL 736 E L+ + E++ + +NDK N+ Q I +++ ++LEK++ ++I++ + Sbjct: 1366 TQNEFLRKENEEMKNQSQLTKADNDKLKEENQNQKEINTKSLMKINELEKLN-KQINDEM 1424 Query: 737 AKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLE 796 AKI + Q+ Q + D+K +D I+ E E +S E I V+E Sbjct: 1425 AKIQNNLQNLTQEKEENDSK---QDEIIKEYEQENETLRSENQNFETKIKVLE------- 1474 Query: 797 RKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKEL---QK 853 K ++L + +K T ++++L +L + + +EK ++E EN L + Sbjct: 1475 -KENKLNVFSLQK------VTKEKEDLAEKLKNQKEVNETLEKAKEDLETENNNLKLNED 1527 Query: 854 KNQILLEENQNLQISLSDMQQHYNALVEKAN---RTDLAESEST--------KYQTQLRD 902 K + +L EN+NL+ L+D+Q+ N LV ++N + E ES+ K + L D Sbjct: 1528 KIKQILSENENLKQKLNDLQKENNDLVNESNDIKQKQKEEMESSKENQNQKEKLENDLND 1587 Query: 903 LESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYE---KNIEYVTQ 959 L+ N + + L+ + K E + E +FN + S ++ N+ + K++E + Sbjct: 1588 LQKNFDELQKSYSDLLEKYKAENDQKESQFN-NVNSNLKQSNYQNDLLQRKLKDLEEEMK 1646 Query: 960 LEAQ----LQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPD--YTEQYINEINK 1013 + + LQ +ENL N++ N L DK ++ + + +Q NEI Sbjct: 1647 NDKEKIDTLQNRNEELENLFGNMKIENSSALANSDKLTKENEALKSENLSLKQTNNEITT 1706 Query: 1014 LNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRV--SKQL 1071 N L + E+I ++ N+ + SD + KL Q + + + + + K+ Sbjct: 1707 KNKELSIELEKIKQNLEENQNSYENVFKEKSDIKEKLDQLIQETNDQKAANKNLLKEKET 1766 Query: 1072 LD--SKQHNEELQILVRE------QDDQIKE-LKETKLTFEMNIPKTEGMIISSTIEPMS 1122 L+ KQ+ +E++ L+++ ++D +KE + E+K + I K + + +T+ S Sbjct: 1767 LEETQKQNQKEIENLIQKVTKLKAKNDFLKENITESKSKLQGEIIKLKEDL--ATMTQKS 1824 Query: 1123 DDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLN 1182 ++ + + + L+++ L E E +I Q+ Sbjct: 1825 NEEKQAQENELSNLKIEHEHLINNFDLLTKGNENLKQKIGNLTQENMESKKEIAQILLEK 1884 Query: 1183 TELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQH 1242 T L + Q +I L+ +E+ ++ + S ++ S + + +++ E E Q Sbjct: 1885 TTLQNQNDSLQNEIENLEKTIEKQKQDSVEIKSKFDQMLSEMKNKMEKNKAENDEK-LQK 1943 Query: 1243 LAQREADFQKTEHELRVQLSAFESKYEQLLDSV-------QSSTQEETNKIVTMEQVT-- 1293 + + +++ QK E+R +++ + + +++ ++ +S +E+ K + +E+V+ Sbjct: 1944 VEEEKSNLQKENEEIREKINKLQEENDEMKENFNESQIMNESFAKEDNEKSLYIEKVSKQ 2003 Query: 1294 --SLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXD 1351 LQN L+ + +NL ++ ++ N E L+SE + + F Sbjct: 2004 NAELQNDLKQLTKENKNLAKQNENLKNSFEKLKSETDILQKNF-DDLQTKFNDLFDDNEQ 2062 Query: 1352 LRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLEL 1411 +E + K + INE+ QL + + E KV E L Sbjct: 2063 KASELEVVKSENSKQFAKINEQKQQL-DNLIKENSSLKVRNELIAKNEQKVSEENENLRT 2121 Query: 1412 KDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENAN 1471 ++ ++ ++ EY +++ +N ++L ++ K +E L+ M+ N Sbjct: 2122 ENEKMKKEIIEY----DEKSQILQNENKKLSLLNDNLQKDLQNKITENDNLK-NMNSNLK 2176 Query: 1472 HYET-MQKESEI--ERVKLIE-ELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALE 1527 + +T + +SEI ++K I LN +E+ SL K+ L + ++ ++ + LE Sbjct: 2177 NDKTNLGNKSEIFENQIKEISASLNKLKSENESLEKEKESLTEENKKLKSENQSQSSELE 2236 Query: 1528 NQEIEIVTLNDEITNLQNMVRASSSKI 1554 + E ++ +E+ L N + KI Sbjct: 2237 KVKSENTSMKNEVEKLANEKSELNKKI 2263 Score = 174 bits (424), Expect = 1e-41 Identities = 316/1509 (20%), Positives = 628/1509 (41%), Gaps = 141/1509 (9%) Query: 144 VTHLSNTIKEKDNALSVLQVKMKIM--ETTIL-DLQEKINEKDQIIEAKNKATTXXXXXX 200 + L T K +N L K+ + E I D +K+ + +Q ++ + T Sbjct: 488 IAKLEATAKIHENEKETLNSKIDYLSKENNIKEDTVKKVQDANQSLKEYKETATKQITDN 547 Query: 201 XXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLE-EANKL 259 + +++ ++ + + + D L+ KD +I ++ EA + Sbjct: 548 TQKFQEILDENQSYREKNAELSRKLLESQKQIDD----LINGFNDKDQQIKGIKGEAGTV 603 Query: 260 LEAARFEISLEHSKLAQ---ELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSL 316 + + E+ E+SKL EL+Q ++ ++ + + +E+K S Sbjct: 604 KQKIK-ELLDENSKLKNKISELDQSLKNSQTAQKQTTLKTQEQLKQNDSLQNILEDKNS- 661 Query: 317 EIANMTELTK----KIELLEHLNCQIRQTNKELE---NKLATMGTESKAVSSPSKKGSPL 369 E+ ++ EL +I L+ +++ N EL+ K+ E + + S K + L Sbjct: 662 ELLSLKELNSTNENQINKLKTKLDNLQKENDELKVSLQKVTERNDELENTTIKSDKANDL 721 Query: 370 ISR--------KSGRNTASKMKSPWSQ--LSSETLNQDT---DKKINKNEIAKLEMVIQS 416 I K +N +K + Q L +E L Q+ +K+I +N L++ Sbjct: 722 IQENMTLKSQMKDAKNENAKTMNEMKQIQLENELLKQNQQNLEKEIKENIQNNLDLQ-NK 780 Query: 417 LNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHME-GPSLIHVGTNTEDV 475 LNK D + V D + L Q +L ++ H + + + D+ Sbjct: 781 LNKIEWDNKIV---SDKLAKEKSSLELQNENLQNQNKLLNENHQKVTEENLAISQKLNDL 837 Query: 476 NEIAKV-QEQLKQ-ELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNH 533 N + K+ Q++L+ L + K+ ++DL +K+++ E++ + E + + ++ Sbjct: 838 NNLNKMCQDELQSTSLTLQRKEKELEDLKQKMENLEKEFYDVKTEKMSMENKIFDLEKES 897 Query: 534 KLKLKQMQKTI-DNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGR 592 K + M K I D ++ D + +LTEE +L K E+E NLQ Sbjct: 898 KNQNDNMNKIIEDKDLQIKDLRTKNEKLTEENSNLQNK----EKENKNLQSR-------- 945 Query: 593 MIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADIS-QLQ 651 +++E EN E K IS + +L + LQ + E +DK ++ Q Sbjct: 946 -------NQIVEKEN-TELSQK-ISSQNERINELENAVSTLQNQILENDDKSQKVTEQTA 996 Query: 652 SDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQ 711 D + + + Q + L + E+ EN D ++ IKDLE++ +D+ ++ Sbjct: 997 KDLIAANSSLKQMTYQNELLQRKQNEM----EN---DLDEKSSRIKDLEDENDDLQKEIL 1049 Query: 712 NYIQENMDLTDKLEKMSAE--KISELLAKINHEEQSKIQTQFGIDAKIQERDL-YIENIE 768 EN ++ EK+S E +I + +I E +S Q K +E + I N + Sbjct: 1050 ELQNENRKISSNYEKISKENNRIEMEMKQIKDENESNKQKLVDNTKKHEEEKMNLINNAK 1109 Query: 769 SELSKYKSR---ICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVN 825 S+ SK I L +I +++D K D S L+ + K +E +++E +N Sbjct: 1110 SDKSKIDGLTKDISMLNSNIKLLQDEN----SKLDNENSQLENEIKKLTEDLQKQNEKIN 1165 Query: 826 RLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKA-- 883 D+ +++ + +ENK+L+ KN++L +EN+ ++ + D N+L EK Sbjct: 1166 ------DNQNLLQN----VTNENKKLKDKNELLFKENEQIKNLMQDKINENNSLKEKQIE 1215 Query: 884 --NRTDLAESESTKYQTQLRDLESNLKRI---THEHQTLIVQKKKEIEDLEIEFNTQIES 938 N + + + + +L+++E++ K T + + Q K + + E ++ + Sbjct: 1216 MENDLNTEKLNNERLVGRLKEIENHNKSKKDNTAKENAKLTQNNKALANENFELKQKVAN 1275 Query: 939 AIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQT 998 ++ + K++K +++ E ++Q+ + E LNK ++ ++ V + Sbjct: 1276 LDQELSDVKNKFDKMSSQISESEKEVQQNAAEFRQIKAKNESLNK-EVQFLNDLVTNLKQ 1334 Query: 999 QSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLE 1058 Q+ D N+ +LN + + I ++I Q ++ ++ E K TK + Sbjct: 1335 QNDDLR----NKKEELNTTFSEDIDNISNELREIKT-QNEFLRKENE-EMKNQSQLTKAD 1388 Query: 1059 N--MEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKET--KLTFEM--NIPKTEGM 1112 N ++EE Q + S EL+ L ++ +D++ +++ LT E N K + + Sbjct: 1389 NDKLKEENQNQKEINTKSLMKINELEKLNKQINDEMAKIQNNLQNLTQEKEENDSKQDEI 1448 Query: 1113 I--ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQE 1170 I E + + N + L V ++ +E+ L E+ K E+ E Sbjct: 1449 IKEYEQENETLRSENQNFETKIKVLEKENK-LNVFSLQKVTKEKEDLAEK-LKNQKEVNE 1506 Query: 1171 CYTKIIQ-LETLNTELT-GHDVVNQ--EQINQLKSKLEQLNTENDNLLSTVAELRSSISS 1226 K + LET N L D + Q + LK KL L EN++L++ +++ Sbjct: 1507 TLEKAKEDLETENNNLKLNEDKIKQILSENENLKQKLNDLQKENNDLVNESNDIKQKQKE 1566 Query: 1227 AVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKI 1286 ++ + + K+ L D QK EL+ S KY+ D +S + + Sbjct: 1567 EMESS--KENQNQKEKLENDLNDLQKNFDELQKSYSDLLEKYKAENDQKESQFNNVNSNL 1624 Query: 1287 VTME-QVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXX 1345 Q LQ KL+D EE ++N +EK + N+ E L + + K+ Sbjct: 1625 KQSNYQNDLLQRKLKDLEEEMKNDKEKIDTLQNRNEELENLFGNMKIENSSALANSDKLT 1684 Query: 1346 XXXXXDLRTENQSYKQMQEQSILNINE---ENAQLKKSSXXXXXXXXXXXXRVNDAEAKV 1402 L++EN S KQ + E E ++K++ +D + K+ Sbjct: 1685 KENEA-LKSENLSLKQTNNEITTKNKELSIELEKIKQNLEENQNSYENVFKEKSDIKEKL 1743 Query: 1403 LEL---THQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKR---IEDLTYEKE 1456 +L T+ + + + ++ T Q E EN+ Q++ + + + +++ E + Sbjct: 1744 DQLIQETNDQKAANKNLLKEKETLEETQKQNQKEIENLIQKVTKLKAKNDFLKENITESK 1803 Query: 1457 SELAILRLKMHENANHYETMQKESEIERVKLIEEL-NVKITESVSLNK--QVAELNKALE 1513 S+L +K+ E+ TM ++S E+ EL N+KI +N + + N+ L+ Sbjct: 1804 SKLQGEIIKLKEDL---ATMTQKSNEEKQAQENELSNLKIEHEHLINNFDLLTKGNENLK 1860 Query: 1514 EEVAKTNE--MQTALENQEI--EIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRD 1569 +++ + M++ E +I E TL ++ +LQN + I+K + + K D Sbjct: 1861 QKIGNLTQENMESKKEIAQILLEKTTLQNQNDSLQNEIENLEKTIEKQKQDSVEIKSKFD 1920 Query: 1570 EQLDNTMNK 1578 + L NK Sbjct: 1921 QMLSEMKNK 1929 Score = 161 bits (392), Expect = 1e-37 Identities = 307/1512 (20%), Positives = 620/1512 (41%), Gaps = 168/1512 (11%) Query: 212 EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271 + K M +M+ + E +++E +L +I S LEE NKLLE + +I E Sbjct: 225 QQLKDSMKEMRATSLEKEKRFQEEILKLKDEIRSLQDNNKMLEEQNKLLEESVKDIHTES 284 Query: 272 SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIA-NMTE-----LT 325 + + L + IE E A + TE L Sbjct: 285 QNILENDNDTIKLNQELAVKDAQLEAKDIEILKLRNALYTENQKFTTAYSQTENRDSPLA 344 Query: 326 KKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSP 385 ++I+ L Q++ N + KL + + + + R N K K Sbjct: 345 EEIKTLTLTMSQLKDENTRNQEKLKKFKDDKLKLKQALHQNE--LDRVKDEN---KYKPQ 399 Query: 386 WSQLSSETLNQDTDKKINKNEI----AKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXX 441 + L+++ N + + K+ I K+ + + + L+++ I++ ++ Sbjct: 400 INDLNTKISNLQKELENAKDTIDAKQKKISTMYERMKAPLLEQNQKINQLESLIDTLNAK 459 Query: 442 XXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEI----KDVN 497 + I L+ Q + S + + AK+ E K+ LN +I K+ N Sbjct: 460 NGKQKDSIKLLKDRISQFQDNNSKLQ--AKIAKLEATAKIHENEKETLNSKIDYLSKENN 517 Query: 498 VK-DLIEKLKSAEEQI--------------TQLNDEIDAANKNMIKVKSNHKLKLKQMQK 542 +K D ++K++ A + + TQ EI N++ + + KL + QK Sbjct: 518 IKEDTVKKVQDANQSLKEYKETATKQITDNTQKFQEILDENQSYREKNAELSRKLLESQK 577 Query: 543 TIDN-FSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSG---------- 591 ID+ + +D +++I + E + QK+ EL +E L+ + + D Sbjct: 578 QIDDLINGFNDKDQQIKGIKGEAGTVKQKIKELLDENSKLKNKISELDQSLKNSQTAQKQ 637 Query: 592 -------RMIESDVYKKMIEMENLAETRLKAI-SLLESQKFDLVQELHILQQKYDEVEDK 643 ++ ++D + ++E +N LK + S E+Q L +L LQ++ DE++ Sbjct: 638 TTLKTQEQLKQNDSLQNILEDKNSELLSLKELNSTNENQINKLKTKLDNLQKENDELKVS 697 Query: 644 LADISQLQSDQVCSEIKS----------VHLEEQI-DALSAS------KKELALVIENLK 686 L +++ + + IKS + L+ Q+ DA + + K++ L E LK Sbjct: 698 LQKVTERNDELENTTIKSDKANDLIQENMTLKSQMKDAKNENAKTMNEMKQIQLENELLK 757 Query: 687 LDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKL--EKMSAEKISELLAK----IN 740 +++ L IK+ + D+ NKL +N ++DKL EK S E +E L +N Sbjct: 758 QNQQNLEKEIKENIQNNLDLQNKLNKIEWDNKIVSDKLAKEKSSLELQNENLQNQNKLLN 817 Query: 741 HEEQSKIQTQFGIDAK--------------IQERDLYIENIESELSKYKSRICRLEESIA 786 Q + I K +Q L ++ E EL K ++ LE+ Sbjct: 818 ENHQKVTEENLAISQKLNDLNNLNKMCQDELQSTSLTLQRKEKELEDLKQKMENLEKEFY 877 Query: 787 VMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEH 846 ++ + S+E K L + + ++ +D + L + L E Sbjct: 878 DVKTEKMSMENKIFDLEKESKNQNDNMNKIIEDKDLQIKDLRTKNEKLTEENSNLQNKEK 937 Query: 847 ENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKAN--RTDLAESE--STKYQTQ-LR 901 ENK LQ +NQI+ +EN L +S + N L + + + E++ S K Q + Sbjct: 938 ENKNLQSRNQIVEKENTELSQKISSQNERINELENAVSTLQNQILENDDKSQKVTEQTAK 997 Query: 902 DL---ESNLKRITHEHQTL----------IVQKKKEIEDLEIEFNTQIESAIRDKKVLNE 948 DL S+LK++T++++ L + +K I+DLE E N ++ I + + N Sbjct: 998 DLIAANSSLKQMTYQNELLQRKQNEMENDLDEKSSRIKDLEDE-NDDLQKEILELQNENR 1056 Query: 949 KYEKNIEYVT----QLEAQLQEYK----NNIENLNMNVEELNKMNLELIDKHVQKQQTQS 1000 K N E ++ ++E ++++ K +N + L N ++ + + LI+ K Sbjct: 1057 KISSNYEKISKENNRIEMEMKQIKDENESNKQKLVDNTKKHEEEKMNLINN--AKSDKSK 1114 Query: 1001 PDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENM 1060 D + I+ +N LL+ ++ ++ N ++ N + K+ L+N+ Sbjct: 1115 IDGLTKDISMLNSNIKLLQDENSKLDNENSQLENEIKKLTEDLQKQNEKINDNQNLLQNV 1174 Query: 1061 EEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEP 1120 E +++ + + NE+++ L++++ ++ LKE ++ E ++ TE + + Sbjct: 1175 TNENKKLKDKNELLFKENEQIKNLMQDKINENNSLKEKQIEMENDL-NTEKLNNERLVGR 1233 Query: 1121 MSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLET 1180 + + N+ L Q + E L+++ A L+ EL + K ++ + Sbjct: 1234 LKEIENHNKSKKDNTAKENAKL-TQNNKALANENFELKQKVANLDQELSDVKNKFDKMSS 1292 Query: 1181 LNTELTGHDVVNQEQINQLKSKLEQLNTE--------------NDNLLSTVAELRSSISS 1226 +E N + Q+K+K E LN E ND+L + EL ++ S Sbjct: 1293 QISESEKEVQQNAAEFRQIKAKNESLNKEVQFLNDLVTNLKQQNDDLRNKKEELNTTFSE 1352 Query: 1227 AVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKI 1286 +D E+ E+ Q+ R K E++ Q ++ ++L + Q+ + T + Sbjct: 1353 DIDNISNELREIKTQNEFLR-----KENEEMKNQSQLTKADNDKLKEENQNQKEINTKSL 1407 Query: 1287 VTMEQVTSLQNKLQDK----EEHLRNL-QEKYADVINQIEILRS-EIEDEKVA-----FX 1335 + + ++ L ++ D+ + +L+NL QEK + Q EI++ E E+E + F Sbjct: 1408 MKINELEKLNKQINDEMAKIQNNLQNLTQEKEENDSKQDEIIKEYEQENETLRSENQNFE 1467 Query: 1336 XXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRV 1395 L+ + + + E+ + N E N L+K+ ++ Sbjct: 1468 TKIKVLEKENKLNVFSLQKVTKEKEDLAEK-LKNQKEVNETLEKAK--EDLETENNNLKL 1524 Query: 1396 NDAEAK-VLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYE 1454 N+ + K +L L+ K +++ ++ ++ L +++ + +++ +E K ++ + Sbjct: 1525 NEDKIKQILSENENLKQKLNDLQKENND----LVNESNDIKQKQKEEMESSKENQNQKEK 1580 Query: 1455 KESELAILRLKMHENANHYETMQKESEIE---RVKLIEELNVKITESVSLNKQVAELNKA 1511 E++L L+ E Y + ++ + E + +N + +S N + K Sbjct: 1581 LENDLNDLQKNFDELQKSYSDLLEKYKAENDQKESQFNNVNSNLKQSNYQNDLLQRKLKD 1640 Query: 1512 LEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQ 1571 LEEE+ E L+N+ E+ L + + A+S K+ K + A ++ +Q Sbjct: 1641 LEEEMKNDKEKIDTLQNRNEELENLFGNMKIENSSALANSDKLTKE-NEALKSENLSLKQ 1699 Query: 1572 LDN---TMNKEL 1580 +N T NKEL Sbjct: 1700 TNNEITTKNKEL 1711 Score = 157 bits (380), Expect = 3e-36 Identities = 300/1428 (21%), Positives = 603/1428 (42%), Gaps = 146/1428 (10%) Query: 234 DEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXX 293 + ++ LKD K++R +SLE+ + E E KL E+ + Sbjct: 221 ESTEQQLKD-SMKEMRATSLEKEKRFQE--------EILKLKDEI-RSLQDNNKMLEEQN 270 Query: 294 XLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMG 353 L ++S++ E I E + I EL K LE + +I + L N L T Sbjct: 271 KLLEESVKDIHTESQNILENDNDTIKLNQELAVKDAQLEAKDIEILK----LRNALYTEN 326 Query: 354 TE-SKAVSSPSKKGSPLISR-KSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLE 411 + + A S + SPL K+ T S++K T NQ+ KK K++ KL+ Sbjct: 327 QKFTTAYSQTENRDSPLAEEIKTLTLTMSQLKD------ENTRNQEKLKKF-KDDKLKLK 379 Query: 412 MVIQSLNKDLVDKEYV----ISEKDTXXXXXXXXXXG-KDTLIA-QLQLEHQ-QHMEGPS 464 + D V E I++ +T KDT+ A Q ++ + M+ P Sbjct: 380 QALHQNELDRVKDENKYKPQINDLNTKISNLQKELENAKDTIDAKQKKISTMYERMKAPL 439 Query: 465 LIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANK 524 L + +N++ E L LN K+ KD I+ LK Q N ++ A Sbjct: 440 L----EQNQKINQL----ESLIDTLN--AKNGKQKDSIKLLKDRISQFQDNNSKLQAKIA 489 Query: 525 NMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAE-----LEEEKG 579 + H+ + + + ID SK ++ ++ V+ ++ + ++ E + + Sbjct: 490 KLEATAKIHENEKETLNSKIDYLSKENNIKEDTVKKVQDANQSLKEYKETATKQITDNTQ 549 Query: 580 NLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDE 639 Q L + S R +++ +K++E + + + + + Q + E ++QK E Sbjct: 550 KFQEILDENQSYREKNAELSRKLLESQKQIDDLINGFNDKDQQIKGIKGEAGTVKQKIKE 609 Query: 640 VEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDL 699 + D+ + + S+ S S ++Q + + + ++N+ DK ++K+L Sbjct: 610 LLDENSKLKNKISELDQSLKNSQTAQKQTTLKTQEQLKQNDSLQNILEDKNSELLSLKEL 669 Query: 700 ENDKEDIMNKLQ----NYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDA 755 + E+ +NKL+ N +EN +L L+K++ E+ EL +++ Q + Sbjct: 670 NSTNENQINKLKTKLDNLQKENDELKVSLQKVT-ERNDELENTTIKSDKANDLIQENMTL 728 Query: 756 KIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKAD-QLGSYLQEK-QKAY 813 K Q +D EN ++ +++ K +LE + + E K + Q LQ K K Sbjct: 729 KSQMKDAKNENAKT-MNEMKQ--IQLENELLKQNQQNLEKEIKENIQNNLDLQNKLNKIE 785 Query: 814 SEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQ 873 + I D+L + L E Q ++++NK L + +Q + EEN + L+D+ Sbjct: 786 WDNKIVSDKLAKEKSSL-------ELQNENLQNQNKLLNENHQKVTEENLAISQKLNDLN 838 Query: 874 QHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEF- 932 ++ T L K L+ NL++ ++ +T + + +I DLE E Sbjct: 839 NLNKMCQDELQSTSLTLQRKEKELEDLKQKMENLEKEFYDVKTEKMSMENKIFDLEKESK 898 Query: 933 --NTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELID 990 N + I DK + + E +T+ + LQ + +NL + + K N EL Sbjct: 899 NQNDNMNKIIEDKDLQIKDLRTKNEKLTEENSNLQNKEKENKNLQSRNQIVEKENTELSQ 958 Query: 991 K------HVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMV- 1043 K + + + Q + +K + +Q +++IA N + Q++Y + + Sbjct: 959 KISSQNERINELENAVSTLQNQILENDDKSQKVTEQTAKDLIAANSSLK--QMTYQNELL 1016 Query: 1044 ----SDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQI---LVREQDDQIK-EL 1095 ++ E+ L + +++++++E+E + K++L+ + N ++ + +++++I+ E+ Sbjct: 1017 QRKQNEMENDLDEKSSRIKDLEDENDDLQKEILELQNENRKISSNYEKISKENNRIEMEM 1076 Query: 1096 KETKLTFEMNIPKTEGMIISSTIEPMS------DDANNVDXXXXXXXXXXXXLKVQEEE- 1148 K+ K E N K E M+ D + +D +K+ ++E Sbjct: 1077 KQIKDENESNKQKLVDNTKKHEEEKMNLINNAKSDKSKIDGLTKDISMLNSNIKLLQDEN 1136 Query: 1149 -EFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHD----------------VV 1191 + E S L+ + KL +LQ+ KI + L +T + + Sbjct: 1137 SKLDNENSQLENEIKKLTEDLQKQNEKINDNQNLLQNVTNENKKLKDKNELLFKENEQIK 1196 Query: 1192 N--QEQINQ---LKSKL----EQLNTE---NDNLLSTVAELRSSISSAVDQRGFEIAELW 1239 N Q++IN+ LK K LNTE N+ L+ + E+ + S D E A+L Sbjct: 1197 NLMQDKINENNSLKEKQIEMENDLNTEKLNNERLVGRLKEIENHNKSKKDNTAKENAKLT 1256 Query: 1240 KQH--LAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQN 1297 + + LA + ++ L +LS ++K++++ + S +E Q+ + +N Sbjct: 1257 QNNKALANENFELKQKVANLDQELSDVKNKFDKMSSQISESEKEVQQNAAEFRQIKA-KN 1315 Query: 1298 KLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQ 1357 + +KE N D++ ++ ++ ++K +++T+N+ Sbjct: 1316 ESLNKEVQFLN------DLVTNLKQQNDDLRNKKEELNTTFSEDIDNISNELREIKTQNE 1369 Query: 1358 ----SYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKD 1413 ++M+ QS L +N +LK+ + ++N+ E +L Q+ + Sbjct: 1370 FLRKENEEMKNQSQLT-KADNDKLKEENQNQKEINTKSLMKINELE----KLNKQINDEM 1424 Query: 1414 SEIYQKTHEYTITLTQRNDEFENVRQQLV-EYEKRIEDLTYEKESELAILRLKMHENANH 1472 ++I LTQ +E ++ + +++ EYE+ E L E ++ +++ EN + Sbjct: 1425 AKIQNNLQ----NLTQEKEENDSKQDEIIKEYEQENETLRSENQNFETKIKVLEKENKLN 1480 Query: 1473 YETMQKESEIERVKLIEEL-NVK-ITESVSLNKQVAEL-NKALEEEVAKTNEMQTALENQ 1529 ++QK ++ E+ L E+L N K + E++ K+ E N L+ K ++ + EN Sbjct: 1481 VFSLQKVTK-EKEDLAEKLKNQKEVNETLEKAKEDLETENNNLKLNEDKIKQILSENENL 1539 Query: 1530 EIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMN 1577 + ++ L E +L N K QK +S Q + E+L+N +N Sbjct: 1540 KQKLNDLQKENNDLVNESNDIKQK-QKEEMESSKENQNQKEKLENDLN 1586 Score = 147 bits (356), Expect = 3e-33 Identities = 287/1442 (19%), Positives = 613/1442 (42%), Gaps = 135/1442 (9%) Query: 155 DNALSVLQVKMKIMETTILDLQEKINEKDQIIEA---KNKATTXXXXXXXXXXXXXXXXX 211 DN S L+ ++K + + EKIN+ +++ +NK Sbjct: 1140 DNENSQLENEIKKLTEDLQKQNEKINDNQNLLQNVTNENKKLKDKNELLFKENEQIKNLM 1199 Query: 212 EDTKQQMTKMQENFIAMEAEWKDEK---QRL---LKDIES--KDVRISSLEEANKLLEAA 263 +D + ++E I ME + EK +RL LK+IE+ K + ++ +E KL + Sbjct: 1200 QDKINENNSLKEKQIEMENDLNTEKLNNERLVGRLKEIENHNKSKKDNTAKENAKLTQNN 1259 Query: 264 RFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTE 323 + ++ E+ +L Q++ ++ Q E E + E ++ N + Sbjct: 1260 K-ALANENFELKQKVANLDQELSDVKNKFDKMSSQISESEKEVQQNAAEFRQIKAKNES- 1317 Query: 324 LTKKIELLEHLNCQIRQTNKELENKLATMGTE-SKAVSSPSKKGSPLISRKS---GRNTA 379 L K+++ L L ++Q N +L NK + T S+ + + S + + ++ N Sbjct: 1318 LNKEVQFLNDLVTNLKQQNDDLRNKKEELNTTFSEDIDNISNELREIKTQNEFLRKENEE 1377 Query: 380 SKMKSPWSQLSSETLNQDTD--KKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXX 437 K +S ++ ++ L ++ K+IN + K+ ++ LNK + D+ I Sbjct: 1378 MKNQSQLTKADNDKLKEENQNQKEINTKSLMKINE-LEKLNKQINDEMAKIQNNLQNLTQ 1436 Query: 438 XXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVN 497 K I + E++Q E +L N E ++ + + +L ++ Sbjct: 1437 EKEENDSKQDEIIK---EYEQ--ENETLRSENQNFETKIKVLEKENKLNVFSLQKVTKEK 1491 Query: 498 VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKL---KLKQMQKTIDNFS-KVSDS 553 +DL EKLK+ +E +N+ ++ A +++ +N KL K+KQ+ +N K++D Sbjct: 1492 -EDLAEKLKNQKE----VNETLEKAKEDLETENNNLKLNEDKIKQILSENENLKQKLNDL 1546 Query: 554 NKEIVRLTEELHHLSQKVAE-LEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETR 612 KE L E + + QK E +E K N + +E+D+ +N E + Sbjct: 1547 QKENNDLVNESNDIKQKQKEEMESSKEN-------QNQKEKLENDLNDLQ---KNFDELQ 1596 Query: 613 LKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLE-----EQ 667 LLE K + Q+ + +++ V L S Q+D + ++K + E E+ Sbjct: 1597 KSYSDLLEKYKAENDQK----ESQFNNVNSNLKQ-SNYQNDLLQRKLKDLEEEMKNDKEK 1651 Query: 668 IDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKM 727 ID L +EL + N+K++ L + E + ++ + Q N ++T K +++ Sbjct: 1652 IDTLQNRNEELENLFGNMKIENSSALANSDKLTKENEALKSENLSLKQTNNEITTKNKEL 1711 Query: 728 SAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAV 787 S E E + + E Q+ + F + I+E+ ++ + E + K+ L + Sbjct: 1712 SIEL--EKIKQNLEENQNSYENVFKEKSDIKEK---LDQLIQETNDQKAANKNLLKEKET 1766 Query: 788 MEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHE 847 +E+ + +++ + L + K KA +++ ++E+ + + ++ ++++++ + Sbjct: 1767 LEETQKQNQKEIENLIQKVT-KLKAKNDF-LKEN--------ITESKSKLQGEIIKLKED 1816 Query: 848 NKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNL 907 + +K+ EE Q + LS+++ + L+ N DL TK L+ NL Sbjct: 1817 LATMTQKSN---EEKQAQENELSNLKIEHEHLI---NNFDLL----TKGNENLKQKIGNL 1866 Query: 908 KRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRD-KKVLNEKYEKNIEYVTQLEAQLQE 966 + E + I Q E L+ + N +++ I + +K + ++ + ++E ++ + L E Sbjct: 1867 TQENMESKKEIAQILLEKTTLQNQ-NDSLQNEIENLEKTIEKQKQDSVEIKSKFDQMLSE 1925 Query: 967 YKNNIE-NLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEI 1025 KN +E N N E+L K+ E ++QK+ + + IN++ + N +K+ E Sbjct: 1926 MKNKMEKNKAENDEKLQKVEEE--KSNLQKENEE----IREKINKLQEENDEMKENFNES 1979 Query: 1026 IALNQ---KINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDS-KQHNEEL 1081 +N+ K +N + Y+ VS ++L +L + + + ++ L +S ++ E Sbjct: 1980 QIMNESFAKEDNEKSLYIEKVSKQNAELQNDLKQLTKENKNLAKQNENLKNSFEKLKSET 2039 Query: 1082 QILVREQDDQIKELKETKLTFEMNIPKTEGM-IISSTIEPMSDDANNVDXXXXXXXXXXX 1140 IL + DD + + F+ N K + ++ S N Sbjct: 2040 DILQKNFDDLQTKFNDL---FDDNEQKASELEVVKSENSKQFAKINEQKQQLDNLIKENS 2096 Query: 1141 XLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLK 1200 LKV+ E E+ V E++ L TE ++ +II+ + + L + + L+ Sbjct: 2097 SLKVRNELIAKNEQKV-SEENENLRTENEKMKKEIIEYDEKSQILQNENKKLSLLNDNLQ 2155 Query: 1201 SKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQ 1260 L+ TENDNL + + L++ ++ ++ +E+++ + + A K L+ + Sbjct: 2156 KDLQNKITENDNLKNMNSNLKNDKTNLGNK-----SEIFENQIKEISASLNK----LKSE 2206 Query: 1261 LSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRN----LQEKYADV 1316 + E + E L + + E ++ +E+V S ++++ E L N L +K +D+ Sbjct: 2207 NESLEKEKESLTEENKKLKSENQSQSSELEKVKSENTSMKNEVEKLANEKSELNKKISDL 2266 Query: 1317 INQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINE---E 1373 QI+ L E D +L N++ K E+S ++N+ E Sbjct: 2267 QEQIDKLTKEKND---------------LSKQNEELVKGNETEKAKNEKSSADLNDFMNE 2311 Query: 1374 NAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDE 1433 N Q+ + + +V + +L K EI + E I + ++ Sbjct: 2312 NKQILADNNRMKEEIQNLKLSAEKCQNEVNRVLEELG-KVVEI-KSLSEIPILFIENKEK 2369 Query: 1434 FENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESE--IERVKLIEEL 1491 E+ + L + I+ + +E+ + + +++H+ + + + + + ++ L Sbjct: 2370 MESTLKLLDNIKSLIKCESNTSNNEIPLKIQNILNDSDHFANIVAKIKKILPEITSVDSL 2429 Query: 1492 NVKITESVSLNKQVAELN-KALEEEVAKT-NEMQTALENQEIEIVTLNDEITNLQNMVRA 1549 +K+ + ELN KAL A++ +E+ + + D TN+Q+++ + Sbjct: 2430 PIKVQIMKDKLTEFEELNDKALNVANARSIHELPNLISKLKQISSNFEDRETNIQSLLDS 2489 Query: 1550 SS 1551 S Sbjct: 2490 YS 2491 Score = 122 bits (295), Expect = 6e-26 Identities = 248/1188 (20%), Positives = 506/1188 (42%), Gaps = 124/1188 (10%) Query: 476 NEIAKVQEQLKQELNDEIKDVNVKDL----IEKLKSAEEQ--ITQLNDEIDAANKNMIK- 528 +EIA+++ QLKQ +I ++ K L I K A+++ I L +I KN I Sbjct: 82 DEIAELKSQLKQADASKITELGEKLLDATSIHAEKEAQQRGCIKMLKAQISELQKNSIPQ 141 Query: 529 -----VKSNHKLKLKQMQKTIDN--FSKVSDSNKEI--VRLT---------EELHHLSQK 570 + LK K + FS VS +I R+ ++ + +K Sbjct: 142 IAMSFSAGSGAKSLKDDCKILKQLIFSYVSQMQSDIHTARIVATALKRACDKKTRKVIRK 201 Query: 571 VAELEE-EKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRL-KAISLLESQKFDLVQ 628 + EL E LQ + ++S D K+M E R + I L+ + L Sbjct: 202 LRELAEIHIPELQTQITQHESTEQQLKDSMKEMRATSLEKEKRFQEEILKLKDEIRSLQD 261 Query: 629 ELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQI---DALSASKKELALVIENL 685 +L+++ +E+ + DI + + ++ ++ L +++ DA +K L + N Sbjct: 262 NNKMLEEQNKLLEESVKDIHTESQNILENDNDTIKLNQELAVKDAQLEAKDIEILKLRNA 321 Query: 686 KLDKEQLYGT-IKDLENDKEDIMNKLQNYI-------QENMDLTDKLEKMSAEKISELLA 737 + Q + T EN + +++ EN +KL+K +K+ +L Sbjct: 322 LYTENQKFTTAYSQTENRDSPLAEEIKTLTLTMSQLKDENTRNQEKLKKFKDDKL-KLKQ 380 Query: 738 KINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYS--L 795 ++ E +++ + +I + + I N++ EL K I ++ I+ M +R + L Sbjct: 381 ALHQNELDRVKDENKYKPQINDLNTKISNLQKELENAKDTIDAKQKKISTMYERMKAPLL 440 Query: 796 E--RKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIE-----HEN 848 E +K +QL S + + L +R++ D++ ++ ++ ++E HEN Sbjct: 441 EQNQKINQLESLIDTLNAKNGKQKDSIKLLKDRISQFQDNNSKLQAKIAKLEATAKIHEN 500 Query: 849 KE--LQKKNQILLEENQNLQISLSDMQQHYNALVE-KANRTDLAESESTKYQTQLRDLES 905 ++ L K L +EN + ++ +Q +L E K T + K+Q ++ D Sbjct: 501 EKETLNSKIDYLSKENNIKEDTVKKVQDANQSLKEYKETATKQITDNTQKFQ-EILDENQ 559 Query: 906 NLKRITHEHQTLIVQKKKEIEDLEIEFN---TQIESAIRDKKVLNEKYEKNIEYVTQLEA 962 + + E +++ +K+I+DL FN QI+ + + +K ++ ++ ++L+ Sbjct: 560 SYREKNAELSRKLLESQKQIDDLINGFNDKDQQIKGIKGEAGTVKQKIKELLDENSKLKN 619 Query: 963 QLQEYKNNIEN-------LNMNVEELNKMN--LE--LIDKHVQKQQTQSPDYT-EQYINE 1010 ++ E +++N + +E K N L+ L DK+ + + + T E IN+ Sbjct: 620 KISELDQSLKNSQTAQKQTTLKTQEQLKQNDSLQNILEDKNSELLSLKELNSTNENQINK 679 Query: 1011 I-NKLNALLKQKDEEIIALNQKI--NNAQVSYMSMVSDYESKLAQFTTKLEN-MEEEMQR 1066 + KL+ L K+ DE ++L QK+ N ++ ++ SD + L Q L++ M++ Sbjct: 680 LKTKLDNLQKENDELKVSL-QKVTERNDELENTTIKSDKANDLIQENMTLKSQMKDAKNE 738 Query: 1067 VSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDAN 1126 +K + + KQ E ++L + Q + KE+KE NI + + + + + D N Sbjct: 739 NAKTMNEMKQIQLENELLKQNQQNLEKEIKE-------NI--QNNLDLQNKLNKIEWD-N 788 Query: 1127 NVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELT 1186 + L + E + +L E K+ E K+ L LN Sbjct: 789 KIVSDKLAKEKSSLEL---QNENLQNQNKLLNENHQKVTEENLAISQKLNDLNNLNKMCQ 845 Query: 1187 GHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQR 1246 + + + +LE L + +NL ++++ S + +I +L K+ Q Sbjct: 846 DELQSTSLTLQRKEKELEDLKQKMENLEKEFYDVKTEKMSMEN----KIFDLEKESKNQN 901 Query: 1247 EADFQKTEHELRVQLSAFESKYEQLLD---SVQSSTQE-----ETNKIVTMEQVTSLQNK 1298 + + K + +Q+ +K E+L + ++Q+ +E N+IV E T L K Sbjct: 902 D-NMNKIIEDKDLQIKDLRTKNEKLTEENSNLQNKEKENKNLQSRNQIVEKEN-TELSQK 959 Query: 1299 LQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQS 1358 + + E + L+ + + NQ IL ++ + +KV DL N S Sbjct: 960 ISSQNERINELENAVSTLQNQ--ILENDDKSQKV------------TEQTAKDLIAANSS 1005 Query: 1359 YKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQ---LELKDSE 1415 KQM Q+ L ++N +++ +D + ++LEL ++ + + Sbjct: 1006 LKQMTYQNELLQRKQN-EMENDLDEKSSRIKDLEDENDDLQKEILELQNENRKISSNYEK 1064 Query: 1416 IYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYET 1475 I ++ + + + Q DE E+ +Q+LV+ K+ +E+E I K ++ T Sbjct: 1065 ISKENNRIEMEMKQIKDENESNKQKLVDNTKK-----HEEEKMNLINNAKSDKSKIDGLT 1119 Query: 1476 MQKESEIERVKLIEELNVKI-TESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIV 1534 +KL+++ N K+ E+ L ++ +L + L+++ K N+ Q L+N E Sbjct: 1120 KDISMLNSNIKLLQDENSKLDNENSQLENEIKKLTEDLQKQNEKINDNQNLLQNVTNENK 1179 Query: 1535 TLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLD 1582 L D+ L + +Q ++ + K+ + +++N +N E L+ Sbjct: 1180 KLKDKNELLFKENEQIKNLMQDKINENNSLKE-KQIEMENDLNTEKLN 1226 Score = 118 bits (284), Expect = 1e-24 Identities = 221/1131 (19%), Positives = 504/1131 (44%), Gaps = 98/1131 (8%) Query: 237 QRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLA---QELEQXXXXXXXXXXXXX 293 Q++ K+ E ++ + +E N+ LE A+ ++ E++ L +++Q Sbjct: 1485 QKVTKEKEDLAEKLKNQKEVNETLEKAKEDLETENNNLKLNEDKIKQILSENENLKQKLN 1544 Query: 294 XLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMG 353 L K++ + E +I++K E+ + E + E LE+ +++ EL+ + + Sbjct: 1545 DLQKENND-LVNESNDIKQKQKEEMESSKENQNQKEKLENDLNDLQKNFDELQKSYSDLL 1603 Query: 354 TESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMV 413 + KA + + S+ + N+ K + + L L +D ++++ KN+ K++ Sbjct: 1604 EKYKAENDQKE------SQFNNVNSNLKQSNYQNDLLQRKL-KDLEEEM-KNDKEKID-T 1654 Query: 414 IQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTE 473 +Q+ N++L + + +++ ++ + L +Q + T + Sbjct: 1655 LQNRNEELENLFGNMKIENSSALANSDKLTKENEALKSENLSLKQTNN-----EITTKNK 1709 Query: 474 DVN-EIAKVQEQLKQELNDEIKDVNVK-DLIEKLKSAEEQITQLNDEIDAANKNMIKVKS 531 +++ E+ K+++ L++ N K D+ EKL ++ I + ND+ AANKN++K K Sbjct: 1710 ELSIELEKIKQNLEENQNSYENVFKEKSDIKEKL---DQLIQETNDQ-KAANKNLLKEKE 1765 Query: 532 NHKLKLKQMQKTIDNF----SKVSDSNKEIVR-LTEELHHLSQKVAELEEEKGNLQLHLV 586 + KQ QK I+N +K+ N + +TE L ++ +L+E+ + Sbjct: 1766 TLEETQKQNQKEIENLIQKVTKLKAKNDFLKENITESKSKLQGEIIKLKEDLATMTQKSN 1825 Query: 587 DYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLAD 646 + + E+++ IE E+L + LL +L Q++ L Q + +E K + Sbjct: 1826 EEKQAQ--ENELSNLKIEHEHL----INNFDLLTKGNENLKQKIGNLTQ--ENMESK-KE 1876 Query: 647 ISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKD-LENDKED 705 I+Q+ ++ + ++ L+ +I+ L + ++ +K +Q+ +K+ +E +K + Sbjct: 1877 IAQILLEKTTLQNQNDSLQNEIENLEKTIEKQKQDSVEIKSKFDQMLSEMKNKMEKNKAE 1936 Query: 706 IMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDA---KIQERDL 762 KLQ +E +L + E++ EKI++L + + +++ ++Q ++ + E+ L Sbjct: 1937 NDEKLQKVEEEKSNLQKENEEIR-EKINKLQEENDEMKENFNESQIMNESFAKEDNEKSL 1995 Query: 763 YIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDE 822 YIE + + ++ ++ + +L + + + +L+ ++L S QK + + + ++ Sbjct: 1996 YIEKVSKQNAELQNDLKQLTKENKNLAKQNENLKNSFEKLKSETDILQKNFDDLQTKFND 2055 Query: 823 LVNRLAVLMDHDRVVE----KQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNA 878 L + VV+ KQ +I + ++L L++EN +L++ +++ Sbjct: 2056 LFDDNEQKASELEVVKSENSKQFAKINEQKQQLDN----LIKENSSLKVR-NELIAKNEQ 2110 Query: 879 LVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLI---VQKKKEIEDLEIEFNTQ 935 V + N E+E K + D +S + + ++ +L+ +QK + + E + Sbjct: 2111 KVSEENENLRTENEKMKKEIIEYDEKSQILQNENKKLSLLNDNLQKDLQNKITENDNLKN 2170 Query: 936 IESAIR-DKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKH-- 992 + S ++ DK L K E + ++ A L + K+ E+L E L + N +L ++ Sbjct: 2171 MNSNLKNDKTNLGNKSEIFENQIKEISASLNKLKSENESLEKEKESLTEENKKLKSENQS 2230 Query: 993 -------VQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSD 1045 V+ + T + E+ NE ++LN + E+I L ++ N+ +V Sbjct: 2231 QSSELEKVKSENTSMKNEVEKLANEKSELNKKISDLQEQIDKLTKEKNDLSKQNEELVKG 2290 Query: 1046 YESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQIL----------VREQDDQIKEL 1095 E++ A+ ++ + M + L D+ + EE+Q L V +++ ++ Sbjct: 2291 NETEKAKNEKSSADLNDFMNENKQILADNNRMKEEIQNLKLSAEKCQNEVNRVLEELGKV 2350 Query: 1096 KETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQ----EEEEF- 1150 E K E+ I E + + D+ ++ LK+Q + + F Sbjct: 2351 VEIKSLSEIPILFIENKEKMESTLKLLDNIKSLIKCESNTSNNEIPLKIQNILNDSDHFA 2410 Query: 1151 ---IQERSVLQEQSA--KLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQ 1205 + + +L E ++ L ++Q K+ + E LN + +V N I++L + + + Sbjct: 2411 NIVAKIKKILPEITSVDSLPIKVQIMKDKLTEFEELNDKAL--NVANARSIHELPNLISK 2468 Query: 1206 LNTENDNLLSTVAELRSSISS-AVDQRGFEIAELWKQHLAQRE-----ADFQKTEHELR- 1258 L + N ++S + S + D+ E++ L K++ Q+ + +E+ L Sbjct: 2469 LKQISSNFEDRETNIQSLLDSYSFDELPAELSRLLKENTDQKALLRSISSIINSENILER 2528 Query: 1259 -VQLSAFESKYEQLLDSVQS-STQEETNKIVTMEQVTSLQNKLQDKEEHLR 1307 +L E E+L + S+ ++ KI + + L+NK+ +KE ++ Sbjct: 2529 CSELIEIEQSMERLKKMCSAISSVDDDRKIEGI--LIDLKNKIDEKERTIQ 2577 Score = 96.3 bits (229), Expect = 6e-18 Identities = 250/1249 (20%), Positives = 533/1249 (42%), Gaps = 138/1249 (11%) Query: 149 NTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXX 208 +T++ ++ L L MKI ++ L +K+ ++++ ++++N + Sbjct: 1653 DTLQNRNEELENLFGNMKIENSSALANSDKLTKENEALKSENLSLKQTNNEITTKNKELS 1712 Query: 209 XXXEDTKQQMTKMQ---ENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARF 265 E KQ + + Q EN +++ K++ +L+++ + +L + + LE + Sbjct: 1713 IELEKIKQNLEENQNSYENVFKEKSDIKEKLDQLIQETNDQKAANKNLLKEKETLEETQK 1772 Query: 266 EISLEHSKLAQEL---------------EQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEI 310 + E L Q++ E LA + + + E++ + Sbjct: 1773 QNQKEIENLIQKVTKLKAKNDFLKENITESKSKLQGEIIKLKEDLATMTQKSNEEKQAQE 1832 Query: 311 EEKGSLEIA------NMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSK 364 E +L+I N LTK E L+ + Q N E + ++A + E + + + Sbjct: 1833 NELSNLKIEHEHLINNFDLLTKGNENLKQKIGNLTQENMESKKEIAQILLEKTTLQNQND 1892 Query: 365 KGSPLISR-----KSGRNTASKMKSPWSQLSSETLNQ-DTDKKINKNEIAKLEMV---IQ 415 I + + + ++KS + Q+ SE N+ + +K N ++ K+E +Q Sbjct: 1893 SLQNEIENLEKTIEKQKQDSVEIKSKFDQMLSEMKNKMEKNKAENDEKLQKVEEEKSNLQ 1952 Query: 416 SLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDV 475 N+++ +K + E++ + A+ E ++E S N E Sbjct: 1953 KENEEIREKINKLQEENDEMKENFNESQIMNESFAKEDNEKSLYIEKVSK----QNAELQ 2008 Query: 476 NEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLN-DEIDAANKNMIKVKSNHK 534 N++ ++ ++ K N ++ N+K+ EKLKS E I Q N D++ ++ Sbjct: 2009 NDLKQLTKENK---NLAKQNENLKNSFEKLKS-ETDILQKNFDDLQTKFNDLFDDNEQKA 2064 Query: 535 LKLKQMQ-KTIDNFSKVSDSNKEIVRLTEELHHL---SQKVAELE----EEKGNLQLHLV 586 +L+ ++ + F+K+++ +++ L +E L ++ +A+ E EE NL+ Sbjct: 2065 SELEVVKSENSKQFAKINEQKQQLDNLIKENSSLKVRNELIAKNEQKVSEENENLRTENE 2124 Query: 587 DYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLAD 646 +IE D ++++ EN K +SLL D +Q+ LQ K E D L + Sbjct: 2125 KMKK-EIIEYDEKSQILQNEN------KKLSLLN----DNLQK--DLQNKITE-NDNLKN 2170 Query: 647 I-SQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKED 705 + S L++D+ KS E QI +SAS +L E+L+ +KE L K L+++ + Sbjct: 2171 MNSNLKNDKTNLGNKSEIFENQIKEISASLNKLKSENESLEKEKESLTEENKKLKSENQS 2230 Query: 706 IMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIE 765 ++L+ EN + +++EK++ EK SEL KI S +Q Q ID +E+ Sbjct: 2231 QSSELEKVKSENTSMKNEVEKLANEK-SELNKKI-----SDLQEQ--IDKLTKEK----- 2277 Query: 766 NIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVN 825 ++LSK EE + E + E+ + L ++ E ++ ++ ++E+ N Sbjct: 2278 ---NDLSKQN------EELVKGNETEKAKNEKSSADLNDFMNENKQILADNNRMKEEIQN 2328 Query: 826 RLAVLMDHDRVVEKQLLEIEH--ENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKA 883 V + L E+ E K L + + +E + ++ +L + + +L++ Sbjct: 2329 LKLSAEKCQNEVNRVLEELGKVVEIKSLSEIPILFIENKEKMESTLK-LLDNIKSLIKCE 2387 Query: 884 NRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIR-- 941 + T E K Q L D + + + I+ + ++ L I+ + Sbjct: 2388 SNTSNNEI-PLKIQNILNDSDHFANIVAKIKK--ILPEITSVDSLPIKVQIMKDKLTEFE 2444 Query: 942 --DKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEEL------NKMNLELIDKHV 993 + K LN ++I + L ++L++ +N E+ N++ L +++ EL + Sbjct: 2445 ELNDKALNVANARSIHELPNLISKLKQISSNFEDRETNIQSLLDSYSFDELPAEL--SRL 2502 Query: 994 QKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQ--VSYMSMVSDYESKLA 1051 K+ T + IN N L ++ E+I + Q + + S +S V D + K+ Sbjct: 2503 LKENTDQKALLRSISSIINSENIL--ERCSELIEIEQSMERLKKMCSAISSVDD-DRKIE 2559 Query: 1052 QFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQD--DQIKELKETKLTFEMNIPKT 1109 L+N +E +R + Q +E L E D ++ ++K + +E I + Sbjct: 2560 GILIDLKNKIDEKER-------TIQTSEALIPPSFEGDLPKKVLQMKNKIIEYEQKISQF 2612 Query: 1110 EGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTE-L 1168 I +P+S ++ +++ + + I ++ S + + + Sbjct: 2613 VNAIGGG--DPISSSRKILESFNNSNSLLTEVIRILKSDPNI---TLTYPFSPSFSAQII 2667 Query: 1169 QECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAEL--RSSISS 1226 ++C+ I +LE N+ + + V+N+ + N + L L++ + E+ R SI Sbjct: 2668 EDCHNLIRKLE--NSVKSINTVLNECKGNGYSG--DDLQEAVHYLVNHLVEIERRKSIEK 2723 Query: 1227 AVDQRGFEIAELWKQHLAQREADFQKTEHEL---RVQLSAFESKYEQLLDSVQSSTQEET 1283 V++ G E+ ++ Q ++ + +KT ++ R Q+ A E +++ D+ + + Sbjct: 2724 HVNEIG-ELRKIHSQEVSILTQNKEKTMEQVKKCREQIIALEKQFQAKEDNYINDLENLK 2782 Query: 1284 NKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKV 1332 + ++ Q ++ K+E + + K AD I + + S+IE + + Sbjct: 2783 TEQYSLSDKLRKQQRI--KDELITFVSGKPAD-IEFLSVNLSDIEKKSI 2828 >UniRef50_Q23QC3 Cluster: Viral A-type inclusion protein repeat containing protein; n=1; Tetrahymena thermophila SB210|Rep: Viral A-type inclusion protein repeat containing protein - Tetrahymena thermophila SB210 Length = 2948 Score = 175 bits (425), Expect = 1e-41 Identities = 301/1485 (20%), Positives = 650/1485 (43%), Gaps = 155/1485 (10%) Query: 220 KMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELE 279 K++EN ++ E D KQ+L + + +S++ + ++ + E+++ + K+ ++ + Sbjct: 1024 KLRENIEQLQQEVDDLKQQLEQAGRENEETVSAITLFKQNSDSQKQELNILNQKIEEQQK 1083 Query: 280 QXXXXXXXXXXXXXX--LAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQ 337 Q +A+++++ EE + M E +++ E++E L Sbjct: 1084 QIQSLLSQKSDLQHLKEVAEENLQLKTEEFDRFRMNLDTDQQVMLEGSEQKEIIESLKKH 1143 Query: 338 IRQTNKELENKLATMGTESKAV--------SSPSKKGSPLISRKSGRNTASKMKSPWSQL 389 I + +L +K + + + + S S+K + + + MK ++L Sbjct: 1144 IEELESQLSDKDFILLQKQQEIIQMNAEKYESSSEKDKLVNKIEELEESVISMKKQ-NKL 1202 Query: 390 SSETLN-----QDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXG 444 + LN QD ++ K++I + + I++L + + D + I EKD Sbjct: 1203 QEQELNECKRLQDEQQEELKSQIKQNNIQIENLKQLIQDMQRQIDEKDDQLEQSQKDKVQ 1262 Query: 445 KDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVN--------EIAKVQEQLKQELNDEIKDV 496 + I QL + +++ + ++ E +++Q +EL + +K+V Sbjct: 1263 NELEIQQLSESNNDYIKEIQALSKQIYSQQAQIHQQKVELEDFDIRKQQFEEL-EHLKEV 1321 Query: 497 NVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKS-----NHKLKLKQMQKTIDNFSKVS 551 + +L ++ E+Q+ L ++ + + ++S N K + ++ +K + Sbjct: 1322 KINELENLIEQYEKQLKNLQEKEEKIEEVCSSLESSVSPINQKSQKQEKEKCEGKQVEEE 1381 Query: 552 DSNKEI-VRLTEELHHLSQKVAELEEEKGNLQLHLVDYDS-GRMIES---DVYKKM---- 602 DS ++ +++ E + Q+ +E+ E+K +QL + + +ES D+ KK Sbjct: 1382 DSKLQLEIQIEEFQEKIQQQESEITEDKQKIQLLEEEVKALQEKLESQQQDLEKKQQEFD 1441 Query: 603 IEMENLAETRLKAISL-LESQKFDLV---QELHILQQKYDEVEDKLADISQ-LQSDQVCS 657 +E++ L ++ K S ES K LV QE+ +QK E+E ++ + + L + Q Sbjct: 1442 LEIQELKKSNQKDDSEEKESLKEQLVEQNQEIVEYKQKLSELEQEVQSLQEKLDTQQKEL 1501 Query: 658 EIKSVHLEEQIDALSASKK-----ELALVIENLKLDKEQLYGTIKDLENDKEDIMNK--- 709 E + + ++I+ L + K E+ ++ + L K L +++LE + N Sbjct: 1502 ERRQIEFNQEIEQLKKANKNEEESEVEVLNQQLTEQKTSLENQVEELEQKLSECQNSITS 1561 Query: 710 LQNYIQENMDLTDKLE--KMSAEKISELLAKIN---HEEQSKIQTQFG-----IDAKIQE 759 LQ IQ+ + KL K+ E+ ++ K+ +EE +K+Q+++ ++E Sbjct: 1562 LQQQIQKQEEEISKLNENKLILEQDNQEFQKMTQQFNEEHTKLQSEYQNILSFYKQAVEE 1621 Query: 760 RDLYIENIESELSKYKSRICR-LEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTI 818 RD NI+ + ++++ + LE+ I+ ++ R + +++ + LQ+K++ +E Sbjct: 1622 RD----NIKQQQQEFETITQKALEDKIS--KENRQNQQQREYEYAQLLQQKEELIAELGK 1675 Query: 819 QEDELVNRLAVLMDHD-------RVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSD 871 + L ++L + R ++ + E E K+L K + ++EN LQ+ L+D Sbjct: 1676 NANNLKDKLTQIEQLSIEQQIAIRSLDTEKKEQEKSIKKLNDKLEFQIQENDQLQL-LTD 1734 Query: 872 MQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKK---EIEDL 928 Q L + N+ ++ E++ ++ ++ E LK + +E++ L ++ + ++E+L Sbjct: 1735 RYQ--KELSKIRNQNEVNENQIKNFKLLKQEQEDQLKELQNENKQLKQRESELQIKVEEL 1792 Query: 929 EIEF-NTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLE 987 E N QI RD++ + ++ E L Q+ E N I+ ++E + N E Sbjct: 1793 ESSLKNIQISQKFRDEQKTSVNNDRQQE---DLNNQINELNNQIDLFKQQIKEQQE-NAE 1848 Query: 988 LIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYE 1047 VQ+ Q Q E EI +L L+ + +I K + + + D + Sbjct: 1849 EQSLRVQQSQEQQLKQKE----EIEELKTKLETFENQIENYKTKEEDLKTQIDDLQQDKD 1904 Query: 1048 SKLAQFTTKLENMEEEMQRVSK--QLLDSKQHNEELQILV---REQDDQIKELKETKLTF 1102 L + T K + ++E +Q+ K +L D E Q+L E+++ +++ + L F Sbjct: 1905 MLLRKKTEKDQRIDELIQQNDKISELCDKLNLQIEQQLLTIRENEENESLQQEQVDNLKF 1964 Query: 1103 EMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQER------SV 1156 ++ KT+ I ++ A N K+++E E ++E+ + Sbjct: 1965 QIEELKTQNDKIQVQSGELA--AQNEAFSIKIQLLENQIAKLKDENELLKEKQPERTHAY 2022 Query: 1157 LQEQSAKLNT-ELQ-ECYTKII--QLETLNTELTGHDVVNQEQIN-----------QLKS 1201 ++ S++ NT EL+ E ++ Q+ N ++ + Q++IN Q +S Sbjct: 2023 SKQSSSEPNTPELEREDNENVLEQQINLPNEKIENQEKEKQQKINFEQKIEADNTLQSQS 2082 Query: 1202 KLEQLNTENDNLLSTVAE---LRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELR 1258 EQ N+ N +++ E L S+ A+++ + A L + L Q+ +++ + + R Sbjct: 2083 ISEQDNSSYQNGIASSPEKEDLIKSLQKALEELKSQ-ASLKENVLNQKLNHYKEKKRQYR 2141 Query: 1259 VQLSAFESKYEQLLDSVQSSTQ---------EETNKIVTMEQVTSLQNKLQDKEEHLRNL 1309 L E KY+++ +++ T+ EE KIV E + N L ++ L Sbjct: 2142 ESLKHSEQKYKEIQYRIETETRTLQTRIQVLEEEQKIVQNESQLQI-NDLSAQKVTLYQE 2200 Query: 1310 QEKYADVINQI--EILRSEI--EDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQ 1365 +K + INQ+ ++ R E+ ++ + D+ ++ + + E Sbjct: 2201 NQKQIEKINQLNEQLKRQELVLQETQRQLRNEQSSARNDSEAVDSDVESKINEIESLTED 2260 Query: 1366 SILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTI 1425 L + EE Q + ++ + K+LE H +SE+ + + Sbjct: 2261 KKL-LKEEIQQKDQLIYQYVEQISDLEKQLQKTQQKLLEGNHNSSPNESELQIMSMQRNE 2319 Query: 1426 TLTQRNDEF----ENVRQQLVEYEKRIEDLT-YEKESELAILRLKMHENANHYETMQKES 1480 T + N+E E V Q + +++I L+ + +E E + L+ N E Q E Sbjct: 2320 TTSSTNEENIFKEEEVNQTIQMLKEQILILSEHAQEKENNLTALQDSINTYLSEKEQYEK 2379 Query: 1481 EIERVK-LIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDE 1539 +I + L E+L ++ E + Q+ ELN E KT +++ L ++ +I+ L E Sbjct: 2380 QIANLNSLNEQLQQQVDELNNFKNQIGELNPQTE----KTEQLENQLSQKDEQILCLEQE 2435 Query: 1540 ITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAV 1584 I L+ ++ ++S S + ++ +E+ DN NK+L + + Sbjct: 2436 INQLKEKIQTANS------SGSGESNSNENEE-DNQKNKDLNELI 2473 Score = 173 bits (422), Expect = 3e-41 Identities = 315/1464 (21%), Positives = 636/1464 (43%), Gaps = 152/1464 (10%) Query: 212 EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLE- 270 ++ ++++T++++ + + +++Q+ L ++ + +E K+LE +I E Sbjct: 842 KELEEKITQLEDQVQVLNTQLAEQQQQHLDHLQQQSELRD--QEILKILEQKTIQIEAEL 899 Query: 271 HSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEE----KGSLEIANMTELTK 326 ++ A +LEQ A+QS + + +E+ K +E + Sbjct: 900 NATFANKLEQEVQSALQQSNNNKEQAEQSQFYQAQYRKVLEDYQQAKKIIESLQKQNQSS 959 Query: 327 KIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPW 386 + E+ EHL QI + ++L+ + A G+ K V ++ LI + T + Sbjct: 960 QKEV-EHLKNQIERITEDLDVQTANQGSTQKYV----QENQALIIKIKELETTN------ 1008 Query: 387 SQLSSETLN-QDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGK 445 ++L+SE N + D K+ +N I +L+ + L + L E E + Sbjct: 1009 NELTSEIFNFEKNDAKLREN-IEQLQQEVDDLKQQL---EQAGRENEETVSAITLFKQNS 1064 Query: 446 DTLIAQLQLEHQ----QHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIK---DVNV 498 D+ +L + +Q Q + SL+ ++ + + E+A+ QLK E D + D + Sbjct: 1065 DSQKQELNILNQKIEEQQKQIQSLLSQKSDLQHLKEVAEENLQLKTEEFDRFRMNLDTDQ 1124 Query: 499 KDLIEKLKSAE--EQITQLNDEIDA--ANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSN 554 + ++E + E E + + +E+++ ++K+ I ++ ++ +Q + + S+ + Sbjct: 1125 QVMLEGSEQKEIIESLKKHIEELESQLSDKDFILLQKQQEI----IQMNAEKYESSSEKD 1180 Query: 555 KEIVRLTEELHHL---SQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAET 611 K +V EEL +K +L+E++ N L D + ++S + + I++ENL + Sbjct: 1181 K-LVNKIEELEESVISMKKQNKLQEQELNECKRLQD-EQQEELKSQIKQNNIQIENLKQL 1238 Query: 612 RL--------KAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVH 663 K L +SQK + EL I QQ + D + +I L S Q+ S+ +H Sbjct: 1239 IQDMQRQIDEKDDQLEQSQKDKVQNELEI-QQLSESNNDYIKEIQAL-SKQIYSQQAQIH 1296 Query: 664 LEE-QIDALSASKKELALV--IENLKLDK-----EQLYGTIKDLENDKEDIMNKLQNYIQ 715 ++ +++ K++ + ++ +K+++ EQ +K+L+ +E I + Sbjct: 1297 QQKVELEDFDIRKQQFEELEHLKEVKINELENLIEQYEKQLKNLQEKEEKIEEVCSSLES 1356 Query: 716 ENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYK 775 + K +K EK K EE SK+Q + I+ + QE+ I+ ESE+++ K Sbjct: 1357 SVSPINQKSQKQEKEKCE---GKQVEEEDSKLQLEIQIE-EFQEK---IQQQESEITEDK 1409 Query: 776 SRICRLEESIAV----MEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLM 831 +I LEE + +E ++ LE+K + +QE +K+ + +E E + V Sbjct: 1410 QKIQLLEEEVKALQEKLESQQQDLEKKQQEFDLEIQELKKSNQKDDSEEKESLKEQLVEQ 1469 Query: 832 DHDRVVEKQ-LLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAE 890 + + V KQ L E+E E + LQ+K +E + QI + Q L +KAN+ + E Sbjct: 1470 NQEIVEYKQKLSELEQEVQSLQEKLDTQQKELERRQI---EFNQEIEQL-KKANKNE-EE 1524 Query: 891 SESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIE--SAIRDKKVLNE 948 SE QL + +++L+ E + + + + I L+ + Q E S + + K++ E Sbjct: 1525 SEVEVLNQQLTEQKTSLENQVEELEQKLSECQNSITSLQQQIQKQEEEISKLNENKLILE 1584 Query: 949 KYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQ---TQSPDYTE 1005 + + + +TQ Q E +++ N+ K +E D Q+QQ T + E Sbjct: 1585 QDNQEFQKMTQ---QFNEEHTKLQSEYQNILSFYKQAVEERDNIKQQQQEFETITQKALE 1641 Query: 1006 QYINEINKLN---------ALLKQKDEEIIALNQKINNA--QVSYMSMVS-DYESKLAQF 1053 I++ N+ N LL+QK+E I L + NN +++ + +S + + + Sbjct: 1642 DKISKENRQNQQQREYEYAQLLQQKEELIAELGKNANNLKDKLTQIEQLSIEQQIAIRSL 1701 Query: 1054 TTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGM- 1112 T+ + E+ +++++ +L Q N++LQ+L D KEL + + E+N + + Sbjct: 1702 DTEKKEQEKSIKKLNDKLEFQIQENDQLQLLT---DRYQKELSKIRNQNEVNENQIKNFK 1758 Query: 1113 IISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECY 1172 ++ E + N + +KV+E E ++ + S K E + Sbjct: 1759 LLKQEQEDQLKELQN-ENKQLKQRESELQIKVEELESSLKNIQI----SQKFRDEQKTSV 1813 Query: 1173 TKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRG 1232 Q E LN ++ +++ NQ + + + K +Q N E +L ++ S + Q+ Sbjct: 1814 NNDRQQEDLNNQI--NELNNQIDLFKQQIKEQQENAEEQSL-----RVQQSQEQQLKQKE 1866 Query: 1233 FEIAEL-WKQHLAQREADFQKT-EHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTME 1290 EI EL K + + + KT E +L+ Q+ + + LL Q I + Sbjct: 1867 -EIEELKTKLETFENQIENYKTKEEDLKTQIDDLQQDKDMLLRKKTEKDQRIDELIQQND 1925 Query: 1291 QVTSLQNKLQDKEEH----LRNLQEKYADVINQIEILRSEIED-----EKVAFXXXXXXX 1341 +++ L +KL + E +R +E + Q++ L+ +IE+ +K+ Sbjct: 1926 KISELCDKLNLQIEQQLLTIRENEENESLQQEQVDNLKFQIEELKTQNDKIQVQSGELAA 1985 Query: 1342 XXXXXXXXXDLRTENQSYKQMQEQSILNINE---ENAQLKKSSXXXXXXXXXXXXRVNDA 1398 L ENQ K E +L + +A K+SS N Sbjct: 1986 QNEAFSIKIQL-LENQIAKLKDENELLKEKQPERTHAYSKQSSSEPNTPELEREDNENVL 2044 Query: 1399 EAKVLELTHQLELKDSEIYQKTH-----EYTITL------TQRNDEFENVRQQLVEYE-- 1445 E ++ ++E ++ E QK + E TL Q N ++N E E Sbjct: 2045 EQQINLPNEKIENQEKEKQQKINFEQKIEADNTLQSQSISEQDNSSYQNGIASSPEKEDL 2104 Query: 1446 -KRIEDLTYEKESELAILRLKMHENANHYETMQ---KESEIERVKLIEELNVKI-TESVS 1500 K ++ E +S+ ++ +++ NHY+ + +ES + +E+ +I TE+ + Sbjct: 2105 IKSLQKALEELKSQASLKENVLNQKLNHYKEKKRQYRESLKHSEQKYKEIQYRIETETRT 2164 Query: 1501 LNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSF 1560 L ++ L EE+ NE Q + + + VTL E + + ++++ Sbjct: 2165 LQTRIQVLE---EEQKIVQNESQLQINDLSAQKVTLYQENQKQIEKINQLNEQLKRQELV 2221 Query: 1561 ASDT-KQGRDEQLDNTMNKELLDA 1583 +T +Q R+EQ + E +D+ Sbjct: 2222 LQETQRQLRNEQSSARNDSEAVDS 2245 Score = 164 bits (399), Expect = 2e-38 Identities = 233/1152 (20%), Positives = 495/1152 (42%), Gaps = 89/1152 (7%) Query: 473 EDVNEIAKVQEQLKQELNDEIKDV-NVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKS 531 ++ + A E+ +QE+ K++ NVK + LK+ + N ++D NK + +KS Sbjct: 613 QNSQQAANKIEKYQQEIELYQKELSNVKQELGNLKNQQTN----NSDLDFLNKQLTNLKS 668 Query: 532 NHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSG 591 K KQ++ I+ SN+ +L E+L Q L+ E L+ L G Sbjct: 669 IFLDKKKQLELEIE------QSNQTHKQLKEKLSQALQSNQSLQSENIMLKNQLSLQTRG 722 Query: 592 RMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQ 651 +D Y K+++ + + I E + L QE+H L+ KYD+ ++ ++ + Sbjct: 723 ---SNDKYNKLMKQDQ------QNIQSFEHENNLLKQEMHNLKSKYDQ---EIEELKEKY 770 Query: 652 SDQVCS-EIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKD--LENDKEDIMN 708 D + S E KS L++Q+ A S + K++ + L KD +E ++DI Sbjct: 771 QDYIFSIEEKSNELKKQL-ADSQNSKQMVKSASGTQNPLATLQLEAKDQIIEQQRQDIFG 829 Query: 709 KLQNYIQEN---MDLTDKLEKM--SAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLY 763 NY +N +L +K+ ++ + ++ LA+ + +Q Q + + + L Sbjct: 830 LECNYRAQNDYIKELEEKITQLEDQVQVLNTQLAEQQQQHLDHLQQQSELRDQEILKILE 889 Query: 764 IENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDEL 823 + I+ E + +LE+ + + + + +A+Q Y + +K +Y Q ++ Sbjct: 890 QKTIQIEAELNATFANKLEQEVQSALQQSNNNKEQAEQSQFYQAQYRKVLEDYQ-QAKKI 948 Query: 824 VNRLAVL-MDHDRVVEKQLLEIEHENKEL------QKKNQILLEENQNLQISLSDMQQHY 876 + L + VE +IE ++L Q Q ++ENQ L I + +++ Sbjct: 949 IESLQKQNQSSQKEVEHLKNQIERITEDLDVQTANQGSTQKYVQENQALIIKIKELETTN 1008 Query: 877 NALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQI 936 N L + E K + + L+ + + + + + ++ + + + F Sbjct: 1009 NELTSEIFN---FEKNDAKLRENIEQLQQEVDDLKQQLEQAGRENEETVSAITL-FKQNS 1064 Query: 937 ESAIRDKKVLNEKYE---KNIEYVTQLEAQLQEYKNNI-ENLNMNVEELNKMNLEL-IDK 991 +S ++ +LN+K E K I+ + ++ LQ K ENL + EE ++ + L D+ Sbjct: 1065 DSQKQELNILNQKIEEQQKQIQSLLSQKSDLQHLKEVAEENLQLKTEEFDRFRMNLDTDQ 1124 Query: 992 HVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLA 1051 V + ++ + E I +L + L KD ++ Q+I + + + S+ Sbjct: 1125 QVMLEGSEQKEIIESLKKHIEELESQLSDKDFILLQKQQEI----IQMNAEKYESSSEKD 1180 Query: 1052 QFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEG 1111 + K+E +EE + + KQ +K +EL R QD+Q +ELK + I + Sbjct: 1181 KLVNKIEELEESVISMKKQ---NKLQEQELNECKRLQDEQQEELKSQIKQNNIQIENLKQ 1237 Query: 1112 MI--ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQ 1169 +I + I+ D L + ++I+E L +Q ++ Sbjct: 1238 LIQDMQRQIDEKDDQLEQSQKDKVQNELEIQQLS-ESNNDYIKEIQALSKQIYSQQAQIH 1296 Query: 1170 ECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLL---STVAELRSSISS 1226 + ++ + + + + + +IN+L++ +EQ + NL + E+ SS+ S Sbjct: 1297 QQKVELEDFDIRKQQFEELEHLKEVKINELENLIEQYEKQLKNLQEKEEKIEEVCSSLES 1356 Query: 1227 AVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKI 1286 +V + + K+ ++ + + ++ +L +Q+ F+ K +Q +S E+ KI Sbjct: 1357 SVSPINQKSQKQEKEKCEGKQVEEEDSKLQLEIQIEEFQEKIQQ----QESEITEDKQKI 1412 Query: 1287 VTM-EQVTSLQNKLQDKEEHLRNLQEKYADVINQI-EILRSEIEDEKVAFXXXXXXXXXX 1344 + E+V +LQ KL+ +++ L Q+++ I ++ + + + +EK + Sbjct: 1413 QLLEEEVKALQEKLESQQQDLEKKQQEFDLEIQELKKSNQKDDSEEKESLKEQLVEQNQE 1472 Query: 1345 XXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLE 1404 L Q + +QE+ L+ ++ + ++ + N+ E++V Sbjct: 1473 IVEYKQKLSELEQEVQSLQEK--LDTQQKELERRQIEFNQEIEQLKKANK-NEEESEVEV 1529 Query: 1405 LTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEK---ESELAI 1461 L QL + + + + E L++ + +++QQ+ + E+ I L K E + Sbjct: 1530 LNQQLTEQKTSLENQVEELEQKLSECQNSITSLQQQIQKQEEEISKLNENKLILEQDNQE 1589 Query: 1462 LRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAE--LNKALEEEVAKT 1519 + KM + N T + +SE + + + V+ +++ +Q E KALE++++K Sbjct: 1590 FQ-KMTQQFNEEHT-KLQSEYQNILSFYKQAVEERDNIKQQQQEFETITQKALEDKISKE 1647 Query: 1520 N---------EMQTALENQEIEIVTLNDEITNLQN-MVRASSSKIQKHVSFAS-DTKQGR 1568 N E L+ +E I L NL++ + + I++ ++ S DT++ Sbjct: 1648 NRQNQQQREYEYAQLLQQKEELIAELGKNANNLKDKLTQIEQLSIEQQIAIRSLDTEKKE 1707 Query: 1569 DEQLDNTMNKEL 1580 E+ +N +L Sbjct: 1708 QEKSIKKLNDKL 1719 Score = 159 bits (387), Expect = 4e-37 Identities = 302/1526 (19%), Positives = 650/1526 (42%), Gaps = 139/1526 (9%) Query: 99 KQK-EILMEKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEK--D 155 KQK ++L E++K +E + + + D + ++KE+ + Sbjct: 1409 KQKIQLLEEEVKALQEKLESQQQDLEKKQQEFDLEIQELKKSNQKDDSEEKESLKEQLVE 1468 Query: 156 NALSVLQVKMKI--METTILDLQEKINEKDQIIEAKN-KATTXXXXXXXXXXXXXXXXXE 212 +++ K K+ +E + LQEK++ + + +E + + E Sbjct: 1469 QNQEIVEYKQKLSELEQEVQSLQEKLDTQQKELERRQIEFNQEIEQLKKANKNEEESEVE 1528 Query: 213 DTKQQMTKMQ---ENFIA-ME---AEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARF 265 QQ+T+ + EN + +E +E ++ L + I+ ++ IS L E +LE Sbjct: 1529 VLNQQLTEQKTSLENQVEELEQKLSECQNSITSLQQQIQKQEEEISKLNENKLILE---- 1584 Query: 266 EISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELT 325 + + E K+ Q+ + KQ++E K + +E E L Sbjct: 1585 QDNQEFQKMTQQFNEEHTKLQSEYQNILSFYKQAVEERDNIKQQQQE---FETITQKALE 1641 Query: 326 KKIELLEHLNCQIR-----QTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTAS 380 KI N Q R Q ++ E +A +G + + + L + + Sbjct: 1642 DKISKENRQNQQQREYEYAQLLQQKEELIAELGKNANNLKDKLTQIEQLSIEQQIAIRSL 1701 Query: 381 KMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXX 440 + + S + LN + +I +N+ +L+++ K+L + Sbjct: 1702 DTEKKEQEKSIKKLNDKLEFQIQEND--QLQLLTDRYQKELSKIRNQNEVNENQIKNFKL 1759 Query: 441 XXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIK-----D 495 ++ + +LQ E++Q + S + + E++ K Q+ Q+ DE K D Sbjct: 1760 LKQEQEDQLKELQNENKQLKQRESELQI--KVEELESSLK-NIQISQKFRDEQKTSVNND 1816 Query: 496 VNVKDLIEKLKSAEEQIT----QLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVS 551 +DL ++ QI Q+ ++ + A + ++V+ + + +LKQ ++ + +K+ Sbjct: 1817 RQQEDLNNQINELNNQIDLFKQQIKEQQENAEEQSLRVQQSQEQQLKQKEEIEELKTKLE 1876 Query: 552 DSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDS--GRMIE-SDVYKKMIEMENL 608 +I + L ++ +L+++K L + D +I+ +D ++ + NL Sbjct: 1877 TFENQIENYKTKEEDLKTQIDDLQQDKDMLLRKKTEKDQRIDELIQQNDKISELCDKLNL 1936 Query: 609 AETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLA-DISQLQSDQVCSEIKSVHLEEQ 667 + + +++ E+++ + +Q+ + K+ E K D Q+QS ++ ++ ++ ++ Q Sbjct: 1937 -QIEQQLLTIRENEENESLQQEQVDNLKFQIEELKTQNDKIQVQSGELAAQNEAFSIKIQ 1995 Query: 668 I--DALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNK-LQNYIQENMDL-TDK 723 + + ++ K E L+ E + ++ Y E + ++ + +N +++ ++L +K Sbjct: 1996 LLENQIAKLKDENELLKEK-QPERTHAYSKQSSSEPNTPELEREDNENVLEQQINLPNEK 2054 Query: 724 LEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEE 783 +E EK ++ + E + +Q+Q Q+ Y I S K + I L++ Sbjct: 2055 IENQEKEKQQKINFEQKIEADNTLQSQ---SISEQDNSSYQNGIASSPEK-EDLIKSLQK 2110 Query: 784 SIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHD-RVVEKQLL 842 ++ ++ + E +Q ++ +EK++ Y E ++ + ++ + R ++ ++ Sbjct: 2111 ALEELKSQASLKENVLNQKLNHYKEKKRQYRESLKHSEQKYKEIQYRIETETRTLQTRIQ 2170 Query: 843 EIEHENKELQKKNQILLEENQNLQISLSDMQQHY----NALVEKANRTDLAESESTKYQT 898 +E E K +Q ++Q+ + + +++L Q N L E+ R +L E+ Q Sbjct: 2171 VLEEEQKIVQNESQLQINDLSAQKVTLYQENQKQIEKINQLNEQLKRQELVLQET---QR 2227 Query: 899 QLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVT 958 QLR+ +S+ + + + + K EIE L E ++ I+ K L +Y +E ++ Sbjct: 2228 QLRNEQSSARNDSEAVDSDVESKINEIESLT-EDKKLLKEEIQQKDQLIYQY---VEQIS 2283 Query: 959 QLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALL 1018 LE QLQ+ + + N N N+ L+++ +Q+ +T S E E ++N + Sbjct: 2284 DLEKQLQKTQQKLLEGNHNSSP-NESELQIMS--MQRNETTSSTNEENIFKE-EEVNQTI 2339 Query: 1019 KQKDEEIIALNQ----KINNAQV------SYMSMVSDYESKLAQFTTKLENMEEEMQRVS 1068 + E+I+ L++ K NN +Y+S YE ++A + E +++++ ++ Sbjct: 2340 QMLKEQILILSEHAQEKENNLTALQDSINTYLSEKEQYEKQIANLNSLNEQLQQQVDELN 2399 Query: 1069 K------QLLDSKQHNEELQILVREQDDQIKELKE--TKLTFEMNIPKTEGMIISSTIEP 1120 +L + E+L+ + ++D+QI L++ +L ++ + G S++ E Sbjct: 2400 NFKNQIGELNPQTEKTEQLENQLSQKDEQILCLEQEINQLKEKIQTANSSGSGESNSNEN 2459 Query: 1121 MSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERS-VLQEQSAKLNTELQECYTKIIQLE 1179 D+ N D ++QE+ F +ER+ L E+ ++ + + + Sbjct: 2460 EEDNQKNKDLNELIESQKEKIQELQEQCTFNEERANQLMEECRAYGVKMADREEEFNKQM 2519 Query: 1180 TLNTELTGHDVVNQ-EQINQLKSKLEQLNTENDNLLSTVAELR----SSISSAVDQRGFE 1234 N E ++ + E+ + L S+ + LN E+ NL + +L+ SS S+ DQ E Sbjct: 2520 ERNDEYYKKLLMRKNEEYSDLYSQYDSLNEESYNLKEEIEKLKNQKNSSSSNNSDQELAE 2579 Query: 1235 IAELWKQHLAQRE-ADFQKTE---------HELRVQLSAFESKYEQLLDSVQSSTQEETN 1284 I K+ + Q+E AD +K E EL+ QL +Y+ L + S Q+ + Sbjct: 2580 IQTKLKEMVVQKEKADQEKEELEKSHNEAIQELKNQLENMRKEYDLLKSLLNSQAQQLIS 2639 Query: 1285 KIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXX 1344 + + VT +K+E L+E N E ++S IE E F Sbjct: 2640 QAYN-QAVT-------EKDEDQSGLKET-----NNSENVKS-IESED--FQPIKQSQSPE 2683 Query: 1345 XXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLE 1404 NQ + + S L I E++ L + ++++ E + L+ Sbjct: 2684 ITPNKQFKAFSNQIHDD-ENSSELGIKVESSDLHEQIQDLKRQIVEKNIKISNLEGENLD 2742 Query: 1405 LTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRL 1464 L Q+ + +Y ++ EY + ++ E QL EY ++ +++ S +L Sbjct: 2743 LEDQV----NSLYAQSQEYRDKINKQYQE----NYQL-EYTQKCQNIKKSYRS-----KL 2788 Query: 1465 KMHENANHYETMQKESEIERVKLIEELNV--KITESVSLNKQV--AELNKALEEEVAKTN 1520 K E E ++ +S+IER + IE V K+ +++ L + ++ + EEE+ K N Sbjct: 2789 KQIEENKKQEMIELKSQIERERNIEMKMVKEKLEKNIQLLDEAYKMQIQQVREEELCKYN 2848 Query: 1521 E-MQTALENQEIEIVTLNDEITNLQN 1545 + +Q + E +I L + QN Sbjct: 2849 QILQEMKQEYEQKIQELKTTLNESQN 2874 Score = 154 bits (374), Expect = 2e-35 Identities = 257/1303 (19%), Positives = 558/1303 (42%), Gaps = 106/1303 (8%) Query: 324 LTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPS---KKGSPLISRKSGRNTAS 380 L KK +L + Q QT+K+L+ KL+ ++++ S + K L +R S Sbjct: 671 LDKKKQLELEIE-QSNQTHKQLKEKLSQALQSNQSLQSENIMLKNQLSLQTRGSNDKYNK 729 Query: 381 KMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXX 440 MK + S + K+ N +K + I+ L + D + I EK Sbjct: 730 LMKQDQQNIQSFEHENNLLKQEMHNLKSKYDQEIEELKEKYQDYIFSIEEKSNELKKQLA 789 Query: 441 XXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKD 500 D+ ++ ++ + P L + +D ++ EQ +Q++ + N + Sbjct: 790 -----DSQNSKQMVKSASGTQNP-LATLQLEAKD-----QIIEQQRQDIFG--LECNYRA 836 Query: 501 LIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRL 560 + +K EE+ITQL D++ N + + + H L+Q + D +EI+++ Sbjct: 837 QNDYIKELEEKITQLEDQVQVLNTQLAEQQQQHLDHLQQQSELRD---------QEILKI 887 Query: 561 TEELHHLSQKVAELEEEKGNLQLHLVDYD-SGRMIESDVYKKMIEMENLAETRLKAISLL 619 L QK ++E E + ++ + + +S+ K+ E + + + + Sbjct: 888 ------LEQKTIQIEAELNATFANKLEQEVQSALQQSNNNKEQAEQSQFYQAQYRKVLED 941 Query: 620 ESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELA 679 Q +++ L QK ++ K + + Q +++ ++ V Q ++ A Sbjct: 942 YQQAKKIIESL----QKQNQSSQKEVEHLKNQIERITEDL-DVQTANQGSTQKYVQENQA 996 Query: 680 LV--IENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLA 737 L+ I+ L+ +L I + E + + ++ QE DL +LE+ E + A Sbjct: 997 LIIKIKELETTNNELTSEIFNFEKNDAKLRENIEQLQQEVDDLKQQLEQAGRENEETVSA 1056 Query: 738 KINHEEQSKIQTQ--FGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDR--RY 793 ++ S Q Q ++ KI+E+ I+++ S+ S + EE++ + + R+ Sbjct: 1057 ITLFKQNSDSQKQELNILNQKIEEQQKQIQSLLSQKSDLQHLKEVAEENLQLKTEEFDRF 1116 Query: 794 SLERKADQLGSYLQEKQKAYSEYTIQE-DELVNRLAVLMDHDRVV---EKQLLEIEHENK 849 + DQ +QK E + +EL ++L+ D D ++ +++++++ E Sbjct: 1117 RMNLDTDQQVMLEGSEQKEIIESLKKHIEELESQLS---DKDFILLQKQQEIIQMNAEKY 1173 Query: 850 ELQKKNQILLEENQNLQISLSDMQQHYNALVEKAN---RTDLAESESTKYQTQLRDLE-S 905 E + L+ + + L+ S+ M++ ++ N R + E K Q + +++ Sbjct: 1174 ESSSEKDKLVNKIEELEESVISMKKQNKLQEQELNECKRLQDEQQEELKSQIKQNNIQIE 1233 Query: 906 NLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQ----LE 961 NLK++ + Q I +K ++E + + Q E I+ N Y K I+ +++ + Sbjct: 1234 NLKQLIQDMQRQIDEKDDQLEQSQKD-KVQNELEIQQLSESNNDYIKEIQALSKQIYSQQ 1292 Query: 962 AQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYIN---EINKLNALL 1018 AQ+ + K +E+ ++ ++ ++ L + + + + Y +Q N + K+ + Sbjct: 1293 AQIHQQKVELEDFDIRKQQFEELE-HLKEVKINELENLIEQYEKQLKNLQEKEEKIEEVC 1351 Query: 1019 KQKDEEIIALNQKINNAQVSYM--SMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQ 1076 + + +NQK + V + +SKL Q ++E +E++Q+ ++ + KQ Sbjct: 1352 SSLESSVSPINQKSQKQEKEKCEGKQVEEEDSKL-QLEIQIEEFQEKIQQQESEITEDKQ 1410 Query: 1077 H----NEELQILVREQDDQIKELKETKLTFEMNIPK-TEGMIISSTIEPMSDDANNVDXX 1131 EE++ L + + Q ++L++ + F++ I + + + E S V+ Sbjct: 1411 KIQLLEEEVKALQEKLESQQQDLEKKQQEFDLEIQELKKSNQKDDSEEKESLKEQLVEQN 1470 Query: 1132 XXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLE--TLNTELTGHD 1189 ++++E + +QE+ L Q +L E +I QL+ N E + + Sbjct: 1471 QEIVEYKQKLSELEQEVQSLQEK--LDTQQKELERRQIEFNQEIEQLKKANKNEEESEVE 1528 Query: 1190 VVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAEL--WKQHLAQRE 1247 V+NQ Q+ + K+ LE E + LS +S+ + ++ EI++L K L Q Sbjct: 1529 VLNQ-QLTEQKTSLENQVEELEQKLSECQNSITSLQQQIQKQEEEISKLNENKLILEQDN 1587 Query: 1248 ADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETN-KIVTMEQVTSLQNKLQDK--EE 1304 +FQK + + + +S+Y+ +L + + +E N K E T Q L+DK +E Sbjct: 1588 QEFQKMTQQFNEEHTKLQSEYQNILSFYKQAVEERDNIKQQQQEFETITQKALEDKISKE 1647 Query: 1305 HLRNLQEK---YADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQ 1361 + +N Q++ YA ++ Q E L +E+ +R+ + K+ Sbjct: 1648 NRQNQQQREYEYAQLLQQKEELIAELGKNANNLKDKLTQIEQLSIEQQIAIRSLDTEKKE 1707 Query: 1362 MQEQSILNINEE-NAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKT 1420 QE+SI +N++ Q++++ + + ++ ++ +Q E+ +++I Sbjct: 1708 -QEKSIKKLNDKLEFQIQENDQLQLL--------TDRYQKELSKIRNQNEVNENQI---- 1754 Query: 1421 HEYTITLTQRND---EFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQ 1477 + + ++ D E +N +QL + E ++ E ES L +++ ++ Sbjct: 1755 KNFKLLKQEQEDQLKELQNENKQLKQRESELQIKVEELESSLKNIQISQKFRDEQKTSVN 1814 Query: 1478 KESEIERV-KLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTL 1536 + + E + I ELN +I +Q+ E + EE+ + + Q Q+ EI L Sbjct: 1815 NDRQQEDLNNQINELNNQID---LFKQQIKEQQENAEEQSLRVQQSQEQQLKQKEEIEEL 1871 Query: 1537 NDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKE 1579 ++ +N + +K + + D +Q +D L K+ Sbjct: 1872 KTKLETFENQIENYKTKEEDLKTQIDDLQQDKDMLLRKKTEKD 1914 Score = 110 bits (264), Expect = 4e-22 Identities = 262/1419 (18%), Positives = 585/1419 (41%), Gaps = 143/1419 (10%) Query: 93 SLANTLKQKEILMEKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIK 152 SL ++++E + K+ + K + ++ + + ++ ++ Sbjct: 1561 SLQQQIQKQEEEISKLNENKLILEQDNQEFQKMTQQFNEEHTKLQSEYQNILSFYKQAVE 1620 Query: 153 EKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXE 212 E+DN Q I + + D K N ++Q + + Sbjct: 1621 ERDNIKQQQQEFETITQKALEDKISKENRQNQ--QQREYEYAQLLQQKEELIAELGKNAN 1678 Query: 213 DTKQQMTKMQENFIAMEAEWKD---EKQRLLKDIESKDVRISSLEEANKLLEAARFEISL 269 + K ++T++++ I + + EK+ K I+ + ++ + N L+ Sbjct: 1679 NLKDKLTQIEQLSIEQQIAIRSLDTEKKEQEKSIKKLNDKLEFQIQENDQLQLLTDRYQK 1738 Query: 270 EHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIE 329 E SK+ + E L KQ E ++ E++ + +EL K+E Sbjct: 1739 ELSKIRNQNE-----VNENQIKNFKLLKQEQE---DQLKELQNENKQLKQRESELQIKVE 1790 Query: 330 LLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQL 389 LE I Q +++ ++ T + + + + L ++ K + ++ Sbjct: 1791 ELESSLKNI-QISQKFRDEQKTSVNNDRQQEDLNNQINELNNQIDLFKQQIKEQQENAEE 1849 Query: 390 SSETLNQDTDKKIN-KNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTL 448 S + Q ++++ K EI +L+ +++ + + Y E+D KD L Sbjct: 1850 QSLRVQQSQEQQLKQKEEIEELKTKLETFENQI--ENYKTKEEDLKTQIDDLQQD-KDML 1906 Query: 449 IAQLQLEHQQHMEGPSLIHVGTNTEDVNEIA-KVQEQLKQEL-----NDEIKDVNVKDLI 502 + + + E Q ++ LI + ++E+ K+ Q++Q+L N+E + + ++ + Sbjct: 1907 LRK-KTEKDQRID--ELIQ---QNDKISELCDKLNLQIEQQLLTIRENEENESLQ-QEQV 1959 Query: 503 EKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTE 562 + LK E++ ND+I + + +K++ ++ I +K+ D N+ + Sbjct: 1960 DNLKFQIEELKTQNDKIQVQSGELAAQNEAFSIKIQLLENQI---AKLKDENELLKEKQP 2016 Query: 563 ELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQ 622 E H K + E L+ D+ ++E + ++EN + + + I+ + Sbjct: 2017 ERTHAYSKQSSSEPNTPELERE----DNENVLEQQINLPNEKIENQEKEKQQKINFEQKI 2072 Query: 623 KFD-LVQELHILQQKYDEVEDKLADISQLQS-----DQVCSEIKS-VHLEEQI--DALSA 673 + D +Q I +Q ++ +A + + + E+KS L+E + L+ Sbjct: 2073 EADNTLQSQSISEQDNSSYQNGIASSPEKEDLIKSLQKALEELKSQASLKENVLNQKLNH 2132 Query: 674 SKKELALVIENLKLDKEQLYGTIK-DLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKI 732 K++ E+LK EQ Y I+ +E + + ++Q ++E + ++ + Sbjct: 2133 YKEKKRQYRESLK-HSEQKYKEIQYRIETETRTLQTRIQ-VLEEEQKIVQNESQLQINDL 2190 Query: 733 SELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRR 792 S + E Q +I+ ++ +++ ++L ++ + +L +S +S AV D Sbjct: 2191 SAQKVTLYQENQKQIEKINQLNEQLKRQELVLQETQRQLRNEQSSA--RNDSEAVDSD-- 2246 Query: 793 YSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQ 852 +E K +++ S L E +K E Q+D+L+ + +Q+ ++E K+LQ Sbjct: 2247 --VESKINEIES-LTEDKKLLKEEIQQKDQLIYQYV----------EQISDLE---KQLQ 2290 Query: 853 KKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITH 912 K Q LLE N N + S++Q + + N T + ST + ++ E N Sbjct: 2291 KTQQKLLEGNHNSSPNESELQ----IMSMQRNET----TSSTNEENIFKEEEVNQTIQML 2342 Query: 913 EHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIE 972 + Q LI+ + + ++ + T ++ +I E+YEK I + L QLQ+ + + Sbjct: 2343 KEQILILSEHAQEKENNL---TALQDSINTYLSEKEQYEKQIANLNSLNEQLQQQVDELN 2399 Query: 973 NLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKI 1032 N + ELN QT+ TEQ N++++ + + ++EI L +KI Sbjct: 2400 NFKNQIGELN-------------PQTEK---TEQLENQLSQKDEQILCLEQEINQLKEKI 2443 Query: 1033 NNAQVSYMSMVSDYES-----KLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVRE 1087 A S + E+ K +E+ +E++Q + +Q +++ +L R Sbjct: 2444 QTANSSGSGESNSNENEEDNQKNKDLNELIESQKEKIQELQEQCTFNEERANQLMEECRA 2503 Query: 1088 QDDQIKELKET-KLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQE 1146 ++ + +E E N + +++ E SD + D ++ + Sbjct: 2504 YGVKMADREEEFNKQMERNDEYYKKLLMRKN-EEYSDLYSQYDSLNEESYNLKEEIEKLK 2562 Query: 1147 EEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQL 1206 ++ + ++ A++ T+L+E ++Q E + E + + E I +LK++LE + Sbjct: 2563 NQKNSSSSNNSDQELAEIQTKLKE---MVVQKEKADQEKEELEKSHNEAIQELKNQLENM 2619 Query: 1207 NTENDNLLSTV-AELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFE 1265 E D L S + ++ + IS A +Q E E ++ ++T + V+ + E Sbjct: 2620 RKEYDLLKSLLNSQAQQLISQAYNQAVTEKDE--------DQSGLKETNNSENVK--SIE 2669 Query: 1266 SKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLR-NLQEKYADVINQIEILR 1324 S + Q Q ++ +I +Q + N++ D E ++ + +D+ QI+ L+ Sbjct: 2670 S------EDFQPIKQSQSPEITPNKQFKAFSNQIHDDENSSELGIKVESSDLHEQIQDLK 2723 Query: 1325 SEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSY-----KQMQEQSILNINEENAQLKK 1379 +I ++ + L ++Q Y KQ QE L ++ +KK Sbjct: 2724 RQIVEKNIKI-SNLEGENLDLEDQVNSLYAQSQEYRDKINKQYQENYQLEYTQKCQNIKK 2782 Query: 1380 SSXXXXXXXXXXXXRVNDAEAKVLELTHQLELK---DSEIYQKTHEYTITLTQR--NDEF 1434 S + + +++EL Q+E + + ++ ++ E I L + Sbjct: 2783 SYRSKLKQIE------ENKKQEMIELKSQIERERNIEMKMVKEKLEKNIQLLDEAYKMQI 2836 Query: 1435 ENVR-QQLVEYEKRIEDLTYEKESELAILRLKMHENANH 1472 + VR ++L +Y + ++++ E E ++ L+ ++E+ N+ Sbjct: 2837 QQVREEELCKYNQILQEMKQEYEQKIQELKTTLNESQNN 2875 Score = 110 bits (264), Expect = 4e-22 Identities = 217/1174 (18%), Positives = 485/1174 (41%), Gaps = 96/1174 (8%) Query: 99 KQKEILMEKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDV--THLSNTIKEKD- 155 +Q++ L E + K+L +R S ++ + D T ++N +++D Sbjct: 1763 EQEDQLKELQNENKQLKQRESELQIKVEELESSLKNIQISQKFRDEQKTSVNNDRQQEDL 1822 Query: 156 -NALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDT 214 N ++ L ++ + + I + QE E+ ++ + Sbjct: 1823 NNQINELNNQIDLFKQQIKEQQENAEEQSLRVQQSQEQQLKQKEEIEELKTKLETFENQI 1882 Query: 215 KQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKL 274 + TK +E+ + + +K LL+ KD RI L + N + +++L+ + Sbjct: 1883 ENYKTK-EEDLKTQIDDLQQDKDMLLRKKTEKDQRIDELIQQNDKISELCDKLNLQIEQQ 1941 Query: 275 AQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHL 334 + + L K IE + +I+ + A + KI+LLE+ Sbjct: 1942 LLTIRENEENESLQQEQVDNL-KFQIEELKTQNDKIQVQSGELAAQNEAFSIKIQLLENQ 2000 Query: 335 NCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETL 394 +++ N+ L+ K T + + S S+ +P + R+ N + + ++ E Sbjct: 2001 IAKLKDENELLKEKQPER-THAYSKQSSSEPNTPELEREDNENVLEQQINLPNE-KIENQ 2058 Query: 395 NQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXG-KDTLIAQLQ 453 ++ +KIN + + + +QS + ISE+D K+ LI LQ Sbjct: 2059 EKEKQQKINFEQKIEADNTLQSQS---------ISEQDNSSYQNGIASSPEKEDLIKSLQ 2109 Query: 454 LEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQEL-NDEIKDVNVKDLIE-KLKSAEEQ 511 + + ++ + + + +N + + Q ++ L + E K ++ IE + ++ + + Sbjct: 2110 -KALEELKSQASLKENVLNQKLNHYKEKKRQYRESLKHSEQKYKEIQYRIETETRTLQTR 2168 Query: 512 ITQLNDEIDAA-NKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQK 570 I L +E N++ +++ K+ Q+ K++ N+++ R +EL L + Sbjct: 2169 IQVLEEEQKIVQNESQLQINDLSAQKVTLYQENQKQIEKINQLNEQLKR--QELV-LQET 2225 Query: 571 VAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETR--LKA-ISLLESQKFDLV 627 +L E+ + + + ++SDV K+ E+E+L E + LK I + + V Sbjct: 2226 QRQLRNEQSSAR------NDSEAVDSDVESKINEIESLTEDKKLLKEEIQQKDQLIYQYV 2279 Query: 628 QELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELAL---VIEN 684 +++ L+++ + + KL + + S SE++ + ++ S +++ + V + Sbjct: 2280 EQISDLEKQLQKTQQKLLEGNHNSSPNE-SELQIMSMQRNETTSSTNEENIFKEEEVNQT 2338 Query: 685 LKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSA------EKISELLAK 738 +++ KEQ+ + + +KE+ + LQ+ I + ++ EK A E++ + + + Sbjct: 2339 IQMLKEQIL-ILSEHAQEKENNLTALQDSINTYLSEKEQYEKQIANLNSLNEQLQQQVDE 2397 Query: 739 INH------EEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRR 792 +N+ E + + ++ ++ ++D I +E E+++ K +I S + + Sbjct: 2398 LNNFKNQIGELNPQTEKTEQLENQLSQKDEQILCLEQEINQLKEKIQTANSSGSGESNSN 2457 Query: 793 YSLE--RKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHE-NK 849 + E +K L ++ +++ E Q R LM+ R ++ + E E NK Sbjct: 2458 ENEEDNQKNKDLNELIESQKEKIQELQEQCTFNEERANQLMEECRAYGVKMADREEEFNK 2517 Query: 850 ELQKKNQILLEENQNLQISLSDMQQHYNALVEKAN--RTDLAESESTKYQTQLRDLESNL 907 ++++ ++ + SD+ Y++L E++ + ++ + ++ K + + + L Sbjct: 2518 QMERNDEYYKKLLMRKNEEYSDLYSQYDSLNEESYNLKEEIEKLKNQKNSSSSNNSDQEL 2577 Query: 908 KRITHEHQTLIVQKKK---EIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQL 964 I + + ++VQK+K E E+LE N I+ + + ++Y+ + QL Sbjct: 2578 AEIQTKLKEMVVQKEKADQEKEELEKSHNEAIQELKNQLENMRKEYDLLKSLLNSQAQQL 2637 Query: 965 --QEYKNNIENLNMNVEELNKMNLELIDKHVQKQ------QTQSPDYTEQYINEINKLNA 1016 Q Y + + + L + N K ++ + Q+QSP+ T N+ K + Sbjct: 2638 ISQAYNQAVTEKDEDQSGLKETNNSENVKSIESEDFQPIKQSQSPEITP---NKQFKAFS 2694 Query: 1017 LLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEE----------MQR 1066 DE L K+ ++ + + D + ++ + K+ N+E E + Sbjct: 2695 NQIHDDENSSELGIKVESSDLH--EQIQDLKRQIVEKNIKISNLEGENLDLEDQVNSLYA 2752 Query: 1067 VSKQLLD--SKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDD 1124 S++ D +KQ+ E Q+ ++ IK+ +KL K E + + S IE + Sbjct: 2753 QSQEYRDKINKQYQENYQLEYTQKCQNIKKSYRSKLKQIEENKKQEMIELKSQIERERNI 2812 Query: 1125 ANNV--DXXXXXXXXXXXXLKVQ----EEEEFIQERSVLQEQSAKLNTELQECYTKIIQL 1178 + + K+Q EEE + +LQE + ++QE T Sbjct: 2813 EMKMVKEKLEKNIQLLDEAYKMQIQQVREEELCKYNQILQEMKQEYEQKIQELKT----- 2867 Query: 1179 ETLNTELTGHDVVNQEQINQLKSKLEQLNTENDN 1212 TLN + N N + + E N N+N Sbjct: 2868 -TLNESQNNNIGNNVNAPNLISDQQEFGNNSNNN 2900 Score = 105 bits (252), Expect = 1e-20 Identities = 173/865 (20%), Positives = 369/865 (42%), Gaps = 84/865 (9%) Query: 742 EEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQ 801 +E S+I + K+ + DL ++N + +K + + ++ I + + L + Sbjct: 590 QENSQISAGKLNNDKMYQEDLLLQNSQQAANKIE----KYQQEIELYQKE---LSNVKQE 642 Query: 802 LGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEE 861 LG+ L+ +Q S+ +L N ++ +D + +E ++ + +K+L++K L+ Sbjct: 643 LGN-LKNQQTNNSDLDFLNKQLTNLKSIFLDKKKQLELEIEQSNQTHKQLKEKLSQALQS 701 Query: 862 NQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQK 921 NQ+LQ S + M ++ +L + + + KY ++ + N++ HE+ L Sbjct: 702 NQSLQ-SENIMLKNQLSLQTRGS--------NDKYNKLMKQDQQNIQSFEHENNLL---- 748 Query: 922 KKEIEDLEIEFNTQIESAIRDK--KVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVE 979 K+E+ +L+ +++ +IE +++K + EK+ E QL A Q K +++ + Sbjct: 749 KQEMHNLKSKYDQEIEE-LKEKYQDYIFSIEEKSNELKKQL-ADSQNSKQMVKSASGTQN 806 Query: 980 ELNKMNLELIDKHVQKQQTQ----SPDYTEQYINEINKLNALLKQKDEEIIALNQKINNA 1035 L + LE D+ +++Q+ +Y Q + I +L + Q ++++ LN ++ Sbjct: 807 PLATLQLEAKDQIIEQQRQDIFGLECNYRAQN-DYIKELEEKITQLEDQVQVLNTQLAEQ 865 Query: 1036 QVSYM------SMVSDYE--SKLAQFTTKLE---------NMEEEMQRVSKQLLDSKQHN 1078 Q ++ S + D E L Q T ++E +E+E+Q +Q ++K+ Sbjct: 866 QQQHLDHLQQQSELRDQEILKILEQKTIQIEAELNATFANKLEQEVQSALQQSNNNKEQA 925 Query: 1079 EELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXX 1138 E+ Q + +++ ++ K E ++ K + +E + + + Sbjct: 926 EQSQFYQAQYRKVLEDYQQAKKIIE-SLQK-QNQSSQKEVEHLKNQIERITEDLDVQTAN 983 Query: 1139 XXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQ 1198 ++++QE L + +L T E ++I E + +L + Q++++ Sbjct: 984 QG-----STQKYVQENQALIIKIKELETTNNELTSEIFNFEKNDAKLRENIEQLQQEVDD 1038 Query: 1199 LKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGF---EIAELWK--QHLAQREADFQ-- 1251 LK +LEQ EN+ +S + + + S + +I E K Q L +++D Q Sbjct: 1039 LKQQLEQAGRENEETVSAITLFKQNSDSQKQELNILNQKIEEQQKQIQSLLSQKSDLQHL 1098 Query: 1252 KTEHELRVQLSAFE-SKYEQLLDSVQSSTQE--ETNKIV--TMEQVTSLQNKLQDKEEHL 1306 K E +QL E ++ LD+ Q E E +I+ + + L+++L DK+ L Sbjct: 1099 KEVAEENLQLKTEEFDRFRMNLDTDQQVMLEGSEQKEIIESLKKHIEELESQLSDKDFIL 1158 Query: 1307 RNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQS 1366 LQ++ + E S E +K+ ++ +N+ +Q + Sbjct: 1159 --LQKQQEIIQMNAEKYESSSEKDKLV------NKIEELEESVISMKKQNKLQEQELNEC 1210 Query: 1367 ILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTIT 1426 +E+ +LK + D + ++ E QLE + Q E Sbjct: 1211 KRLQDEQQEELKSQIKQNNIQIENLKQLIQDMQRQIDEKDDQLEQSQKDKVQNELEIQQL 1270 Query: 1427 LTQRND---EFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIE 1483 ND E + + +Q+ + +I E E +R + E H + + K +E+E Sbjct: 1271 SESNNDYIKEIQALSKQIYSQQAQIHQQKVELED--FDIRKQQFEELEHLKEV-KINELE 1327 Query: 1484 RVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNL 1543 LIE+ ++ +++ E+ +LE V+ N+ E ++ E + +E + L Sbjct: 1328 --NLIEQYEKQLKNLQEKEEKIEEVCSSLESSVSPINQKSQKQEKEKCEGKQVEEEDSKL 1385 Query: 1544 QNMVRAS--SSKIQKHVSFASDTKQ 1566 Q ++ KIQ+ S ++ KQ Sbjct: 1386 QLEIQIEEFQEKIQQQESEITEDKQ 1410 Score = 66.1 bits (154), Expect = 8e-09 Identities = 156/783 (19%), Positives = 310/783 (39%), Gaps = 68/783 (8%) Query: 807 QEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQ 866 Q++Q S+ T + +L A L+ ++ + + + + + Q++NQ L ++NQ Sbjct: 280 QQQQPQQSQQTKNQQQL-QHYAALVAQSNLMVQNMQQQQQQLLIKQEQNQHLQQQNQ--L 336 Query: 867 ISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIE 926 S ++ + N + K + + A Q++ ++ + + +K I Sbjct: 337 NSPQNVLSNNNTIGYKQVKQEQAYRYGRVLPNQMQVYDNAPLFPAQQQKAKETFYQKLIT 396 Query: 927 DLEIE-FNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMN 985 D + FN ++ ++ LN+ T + Q +N L +++ Sbjct: 397 DRNFQNFNQKLHVKKNQEQQLNQPQ-------TNIPVNSQSVRNKTIKLQFAQSLWHRIQ 449 Query: 986 LELIDKHVQKQQT-QSPDYTEQYINEINKLNALLKQ---------KDEEIIALN----QK 1031 + H Q++ Q+ T Q++ NK ++ Q KD ALN Q Sbjct: 450 TRNLSAHQSPQESFQNIPKTLQFVTYNNKYQPIIPQSNIQANHQKKDSLDQALNHLLKQN 509 Query: 1032 INNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVS--KQLLDSKQHNEELQILVREQD 1089 I N + + ++ +L QF + + E+ Q+ S+ H + +E D Sbjct: 510 IPNNTIPLEQLEMRHKKQLDQFKQQAQRYEQSSSHKGGRLQMSFSESHTPRKNSISKESD 569 Query: 1090 D-QIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXL-KVQEE 1147 + K +FE E IS+ + +D D + K Q+E Sbjct: 570 GVGARSNSMQKKSFENFNSSQENSQISAG-KLNNDKMYQEDLLLQNSQQAANKIEKYQQE 628 Query: 1148 EEFIQ-ERSVLQEQSAKL------NTELQECYTKIIQLETLNTELTGHDVVNQEQIN--- 1197 E Q E S ++++ L N++L ++ L+++ + + EQ N Sbjct: 629 IELYQKELSNVKQELGNLKNQQTNNSDLDFLNKQLTNLKSIFLDKKKQLELEIEQSNQTH 688 Query: 1198 -QLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHE 1256 QLK KL Q N +L S L++ +S + RG + + + + Q + + Q EHE Sbjct: 689 KQLKEKLSQALQSNQSLQSENIMLKNQLS--LQTRGSN--DKYNKLMKQDQQNIQSFEHE 744 Query: 1257 ---LRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKY 1313 L+ ++ +SKY+Q ++ ++ Q+ I E+ L+ +L D ++ + + + Sbjct: 745 NNLLKQEMHNLKSKYDQEIEELKEKYQDYIFSI--EEKSNELKKQLAD-SQNSKQMVKSA 801 Query: 1314 ADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXD-LRTENQSYKQMQEQ-SILNIN 1371 + N + L+ E +D+ + D ++ + Q+++Q +LN Sbjct: 802 SGTQNPLATLQLEAKDQIIEQQRQDIFGLECNYRAQNDYIKELEEKITQLEDQVQVLNTQ 861 Query: 1372 EENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRN 1431 Q + + E K +++ + EL + + E L Q N Sbjct: 862 LAEQQQQHLDHLQQQSELRDQEILKILEQKTIQI--EAELNATFANKLEQEVQSALQQSN 919 Query: 1432 DEFENVRQQ---LVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLI 1488 + E Q +Y K +ED Y++ ++ I L+ ++ E +++IER+ Sbjct: 920 NNKEQAEQSQFYQAQYRKVLED--YQQAKKI-IESLQKQNQSSQKEVEHLKNQIERI--T 974 Query: 1489 EELNVKITESVSLNKQVAELNKAL----EEEVAKTNEMQTALENQEIEIVTLNDEITNLQ 1544 E+L+V+ S K V E N+AL +E NE+ + + N E L + I LQ Sbjct: 975 EDLDVQTANQGSTQKYVQE-NQALIIKIKELETTNNELTSEIFNFEKNDAKLRENIEQLQ 1033 Query: 1545 NMV 1547 V Sbjct: 1034 QEV 1036 >UniRef50_A2EZE6 Cluster: Viral A-type inclusion protein, putative; n=1; Trichomonas vaginalis G3|Rep: Viral A-type inclusion protein, putative - Trichomonas vaginalis G3 Length = 2098 Score = 175 bits (425), Expect = 1e-41 Identities = 314/1547 (20%), Positives = 652/1547 (42%), Gaps = 136/1547 (8%) Query: 94 LANTLKQKEILMEKIKQ--YKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVT-HLSNT 150 LA +K+K+IL+ +++ YK SK + + + QL T ++ Sbjct: 47 LAQKIKEKDILIRSLQEENYKYRSKANQVSREQANEEKISQLGLKFQKQLNQKTLQYASQ 106 Query: 151 IKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXX 210 + + ++S L+ ++K + T + + + K+ + +AK +AT Sbjct: 107 LSAQAKSISDLEAQVKKLNTELENTEVKLQTASKKQKAKLQATIKEKQAQIDTLNERIAQ 166 Query: 211 XEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLE 270 ++ K E++ + + Q L ++I+SKDV I LE N + E +I+ Sbjct: 167 DSILYEESAKQLESY-------QQQIQSLNEEIKSKDVSI--LERDNTIRELEN-KINDI 216 Query: 271 HSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEI-ANMTELTKKIE 329 K+ Q+ +Q L K E +K S ++ ++ EL +K+ Sbjct: 217 VGKVDQKFKQSKDAIAEKEKIVAQLKKDPKNEGIVAAIEKADKSSSQLNESVNELQEKLS 276 Query: 330 LLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSG----RNTASKMKSP 385 + + + +L+ + + S+ K + + ++ ++ KM Sbjct: 277 KSQINGDESEVSASQLDISINKNDSASELCEIIQNKDNRIKELEAAVEELKHKPMKMNDI 336 Query: 386 WSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGK 445 +Q S E Q + +I++ EI +L+ Q+L K++ ++EK K Sbjct: 337 -AQNSQENALQ-SQIEIHEQEIEELQATNQALEKEIEILNQRLAEKSDKTLNERISYLEK 394 Query: 446 DT--LIAQLQLEHQQHMEGPSLIH-----VGTNTEDVNEIAKVQE---QLKQEL---NDE 492 + +++ + + Q + S I+ + + +I +Q +LK+ L + E Sbjct: 395 ELSKTLSENETQKTQINDFTSRINKYKAELDAKVDQEAQILTLQTLNTELKESLANKDKE 454 Query: 493 IKDVNV---KDLIEKLKSAEEQITQLNDEIDAANKNMIKVK---------SNHKLKLKQM 540 I D+ KDL S ++ ++ N + D N + + V N LK Sbjct: 455 IADLKALLDKDLSSNAGSPVKKASKTNTDEDEVNTSALDVTIDSPKQLKGENEDLKADNQ 514 Query: 541 QKTIDNFSKVSDSNK---EIVRLTEELHHLSQKVAELEE---EKGNLQLHLVDYDSG--R 592 + +N DS+K E +LTEEL +L +++AEL+E EKG+ + +S + Sbjct: 515 KLKQENDKLKQDSDKTSQENQKLTEELENLRKQLAELQEKSKEKGSDDSFSQELNSSLNQ 574 Query: 593 MIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQ--L 650 + E+ + K E+E L + L E+Q V++ LQ + ++ L S Sbjct: 575 VNEAIIQSKDEEIEELKGKLAELNGLFEAQ----VKQNEDLQAENTKLTQALEMFSNNDT 630 Query: 651 QSDQVCSEIKSVH-LEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNK 709 S V + H L+E+I L + + + +NL+ D ++ I ++E + E + Sbjct: 631 SSSPVSAAKNFKHSLDEKIANLQDAVNKYREITDNLQNDNDEKAELIVNMEKEAEAFAER 690 Query: 710 LQNYIQENMDLTDKLEKMSAE--KIS-ELLAKINHEEQSK-----IQTQFGIDAKIQERD 761 + +Y E ++E++ AE K+ EL AK EQ K +Q + + ++QE + Sbjct: 691 INHYKSEIDSKDSEIERLKAEIDKLKGELAAKNTEAEQIKGQISDLQYKLSANGQMQEEN 750 Query: 762 ----LYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAY---- 813 I +++ EL ++I LE + + D+ +++ D L +EK + + Sbjct: 751 NSLAKQIADLQKELENKANQIKDLESRLNSLNDQNELKQKEIDALKKQFREKSEQFDLLN 810 Query: 814 SEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKE-LQKKNQI--LLEENQNLQISLS 870 SE E + + + ++E++ EIE E QK QI L +EN+ + + Sbjct: 811 SEINKLRSENEEKSKEINQNKALIEEKTKEIEALKAENAQKSQQINALSQENEQKKKQID 870 Query: 871 DM--------QQHYNALVE---KANRTDLAESESTKYQTQLRDL----ESNLKRITHEHQ 915 ++ +Q N VE K + D E+ + Q+ DL E N K+I + + Sbjct: 871 NLSVENEQKKKQIDNLSVENEQKKKQIDNLSEENKLNKKQIDDLAEKNEQNEKQINNLSE 930 Query: 916 TLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLN 975 QKKK+I++L E N Q + I D L+E+ + E + ++E+++++ N+ E Sbjct: 931 QN-EQKKKQIDNLSEE-NKQNKRQIDD---LSEENKLGKEKMNKIESEIRKVVNDTEMTP 985 Query: 976 MNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNA 1035 + + + K K ++ ++ KL+ L K+KDE +I+ QK Sbjct: 986 VRLTSKFVADANEKKKDNAKLLEENKALSKAIDELQQKLDELHKEKDE-LISQAQKNQQE 1044 Query: 1036 QVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQ---- 1091 + + + +SKLA++ L+++++E + +++ N+ ++ + R++ +Q Sbjct: 1045 KEEFGQFI---KSKLAEYADNLKSLDKERKEKDQEI---NALNDTIEAMRRQEIEQASHH 1098 Query: 1092 ---IKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEE 1148 + +L T + E I + + + + E + N + K +E E Sbjct: 1099 YKDMSDLHNTNKSLEKQIEEMKEKVTNDD-EEVRLQLQNKEREITASKLMITN-KEKENE 1156 Query: 1149 EFIQERSVLQEQSAKLNTELQECYTKIIQLE---TLNT-ELTGHD---VVNQEQINQLKS 1201 E ++ L+E++ KL E+QE ++ L+ T+NT EL +IN L Sbjct: 1157 ELKKQNEELKEKTEKLQKEVQEKEGEVNSLKLTFTMNTQELEKQKKEFAAKDTEINNLNQ 1216 Query: 1202 KLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQL 1261 ++++LN E + + S + ++ S + ++ + + Q A++ D Q ++ ++ Sbjct: 1217 EIQKLNQEAEKVTSELQKVTSDLQKVTEENAKKQEQEEDQSSAEKIQDLQSDIFNMKREI 1276 Query: 1262 SAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIE 1321 + E +Q S ++ET+KI E++ L++ ++ R L++++ + + Sbjct: 1277 KTLKDDIENKEKEIQKS-KDETSKI--NEELNKLKSDKSKLDKENRTLKDQF----EKQK 1329 Query: 1322 ILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSS 1381 IL S ++++ + ++Q+ ++I + K + Sbjct: 1330 ILVSALQEQNNQSKFEEENKNLKTQLSAAKSEKSKLQQENTEKQNQIDILTAETERKSNQ 1389 Query: 1382 XXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQL 1441 D + L + + + K E L + E E ++ QL Sbjct: 1390 IRSHLTEIEQLKSKLDGQTNSLNDLKTYKQQSEQFNSKLDELQKNLAKAMKEKEEIQTQL 1449 Query: 1442 VEYEKRIEDLTYEKES---ELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITES 1498 E K E++ + + + L+ ++ + YE ++ +S + + EEL K+ + Sbjct: 1450 TESNKEKEEMQQKLDDGFRQFEELQDSYNQGMSKYEELE-QSYNQGMAQNEELKKKLNDE 1508 Query: 1499 VSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQN 1545 + NK EL+K + E ++ E+ T L+ + IV+L +E+ Q+ Sbjct: 1509 IKDNK---ELDKNMHELMSTNYEIDTQLKAAKQRIVSLEEEMKQFQS 1552 Score = 171 bits (416), Expect = 1e-40 Identities = 291/1352 (21%), Positives = 584/1352 (43%), Gaps = 137/1352 (10%) Query: 307 KTEIEEKGSLEIANM-TELTKKIELLEHLNCQIRQTN---KELENKLATMGTESKAVSSP 362 K+EI+ K S EI + E+ K L N + Q +L+ KL+ G + +S Sbjct: 695 KSEIDSKDS-EIERLKAEIDKLKGELAAKNTEAEQIKGQISDLQYKLSANGQMQEENNSL 753 Query: 363 SKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLV 422 +K+ + L +K N A+++K S+L+S LN + K + + K + +S DL+ Sbjct: 754 AKQIADL--QKELENKANQIKDLESRLNS--LNDQNELKQKEIDALKKQFREKSEQFDLL 809 Query: 423 DKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQ 482 + E I++ + LI E + +E + ++ +N +++ Sbjct: 810 NSE--INKLRSENEEKSKEINQNKALIE----EKTKEIEALKAENA-QKSQQINALSQEN 862 Query: 483 EQLKQELND-EIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQ 541 EQ K+++++ +++ K I+ L EQ + D + NK K + K +Q + Sbjct: 863 EQKKKQIDNLSVENEQKKKQIDNLSVENEQKKKQIDNLSEENKLNKKQIDDLAEKNEQNE 922 Query: 542 KTIDNFSKVSDSNK-EIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYK 600 K I+N S+ ++ K +I L+EE +++ +L EE + + + IES++ + Sbjct: 923 KQINNLSEQNEQKKKQIDNLSEENKQNKRQIDDLSEE------NKLGKEKMNKIESEI-R 975 Query: 601 KMIEMENLAETRL--KAISLLESQKFD---LVQELHILQQKYDEVEDKLADISQLQSDQV 655 K++ + RL K ++ +K D L++E L + DE++ KL ++ + + + + Sbjct: 976 KVVNDTEMTPVRLTSKFVADANEKKKDNAKLLEENKALSKAIDELQQKLDELHKEKDELI 1035 Query: 656 CSEIKSVHLEEQIDALSASKKELALVIENLK-LDKEQLYGTIKDLE-NDKEDIMNKLQNY 713 K+ +E+ SK LA +NLK LDKE+ KD E N D + ++ Sbjct: 1036 SQAQKNQQEKEEFGQFIKSK--LAEYADNLKSLDKERKE---KDQEINALNDTIEAMRR- 1089 Query: 714 IQENMDLTDKLEKMS-AEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELS 772 QE + + MS ++ L K E + K+ D +++ L ++N E E++ Sbjct: 1090 -QEIEQASHHYKDMSDLHNTNKSLEKQIEEMKEKVTND---DEEVR---LQLQNKEREIT 1142 Query: 773 KYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSE----YTIQEDELVNRLA 828 K I E+ ++ + L+ K ++L +QEK+ + +T+ EL + Sbjct: 1143 ASKLMITNKEKENEELKKQNEELKEKTEKLQKEVQEKEGEVNSLKLTFTMNTQELEKQKK 1202 Query: 829 VLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDL 888 D EI + N+E+QK NQ + LQ SD+Q+ E A + + Sbjct: 1203 EFAAKDT-------EINNLNQEIQKLNQEAEKVTSELQKVTSDLQK---VTEENAKKQEQ 1252 Query: 889 AESESTKYQTQLRDLESNLKRITHEHQTL---IVQKKKEIE---DLEIEFNTQIESAIRD 942 E +S+ + Q DL+S++ + E +TL I K+KEI+ D + N ++ D Sbjct: 1253 EEDQSSAEKIQ--DLQSDIFNMKREIKTLKDDIENKEKEIQKSKDETSKINEELNKLKSD 1310 Query: 943 K-------KVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVE----ELNKMNLELIDK 991 K + L +++EK V+ L+ Q + K EN N+ + + K L+ + Sbjct: 1311 KSKLDKENRTLKDQFEKQKILVSALQEQNNQSKFEEENKNLKTQLSAAKSEKSKLQQENT 1370 Query: 992 HVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLA 1051 Q Q TE+ N+I ++Q ++ +N+ + +Y + SKL Sbjct: 1371 EKQNQIDILTAETERKSNQIRSHLTEIEQLKSKLDGQTNSLNDLK-TYKQQSEQFNSKLD 1429 Query: 1052 QFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTE- 1110 + L +E + + QL +S + EE+Q ++ DD ++ +E + ++ + K E Sbjct: 1430 ELQKNLAKAMKEKEEIQTQLTESNKEKEEMQ---QKLDDGFRQFEELQDSYNQGMSKYEE 1486 Query: 1111 -------GMIISSTIEPMSDDA--------NNVDXXXXXXXXXXXXLKVQEEEEFIQERS 1155 GM + ++ +D N+ LK ++ E Sbjct: 1487 LEQSYNQGMAQNEELKKKLNDEIKDNKELDKNMHELMSTNYEIDTQLKAAKQRIVSLEEE 1546 Query: 1156 VLQEQSAKLNTELQECYTKIIQLETLNTELTGH--DVVNQ------------EQINQLKS 1201 + Q QS +++L++ +K+I+L N + D++ + ++ N +KS Sbjct: 1547 MKQFQSNDHSSDLEQLKSKLIELTKENNSIKSRNEDLIEENKSVKSKVDELSKENNSIKS 1606 Query: 1202 KLEQLNTENDNLLSTVAEL---RSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHE-- 1256 K+ +LN EN S + EL S+ S + +R EI E+ K LA++ + ++TE++ Sbjct: 1607 KVNELNNENSKSKSRIDELIKANDSLKSQLQERANEI-EIIKSELAEKSKE-KETENDEI 1664 Query: 1257 --LRVQLSAFESKYEQL---LDSVQSSTQEETNKIVTMEQVTSLQNK-LQDKEEHLRNLQ 1310 L+ +L + + ++L L ++ + E ++ + + NK L + E + L+ Sbjct: 1665 KKLKSELKDSQKQCDELHRNLHNLMNENGELKSQNSQLSKDFETNNKKLLNLENAKKQLE 1724 Query: 1311 EKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRT-ENQSYKQMQEQSILN 1369 +K AD + + +++ A L +N++ K+ E Sbjct: 1725 QKLADNTKSQNDMFANYQEQIEALGQKIISLEEEDAELNRQLNELKNENNKEEMENKEKE 1784 Query: 1370 INEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQ 1429 +E A+ + +N+ +++E +H+ E + + ++ E L Sbjct: 1785 KDELLAEKNRKIDEAEKEFNEQIKHLNEQIQELIEDSHEKENNNENLAKENSELIQKLNS 1844 Query: 1430 RNDEFENVRQQLVEYEKRIE-DLTYEKESELAILRLKMHENANHYETMQKESEIERVKLI 1488 ++E ++++ V + ++ + Y ++ + I L N E ++ E EI K Sbjct: 1845 LHEEIKSLKASNVSQKVELDQNKEYIQKRQKDIDLLNEEYNNLFNEKLEFEFEINSQK-- 1902 Query: 1489 EELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVR 1548 +ELN K S +N Q E++ ++ NE Q + + EI + ++I L ++ Sbjct: 1903 DELNNK---SQYINNQKNEIDNLKKQN----NEKQNEIAKLQKEIDSYQEKIDKLISLNE 1955 Query: 1549 ASSSKIQKHVSFASDTKQGRDEQLDNTMNKEL 1580 ++K+ ++ RD +L++ E+ Sbjct: 1956 EKNNKLTNLAKQQQYAQKNRDLELNDGNENEI 1987 Score = 167 bits (407), Expect = 2e-39 Identities = 336/1609 (20%), Positives = 695/1609 (43%), Gaps = 180/1609 (11%) Query: 99 KQKEILMEKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNAL 158 K+ EIL +++ + + + + + Q+ D T N K + +A Sbjct: 368 KEIEILNQRLAEKSDKTLNERISYLEKELSKTLSENETQKTQINDFTSRINKYKAELDAK 427 Query: 159 SVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQM 218 + ++ ++T +L+E + KD+ I A KA +T + Sbjct: 428 VDQEAQILTLQTLNTELKESLANKDKEI-ADLKALLDKDLSSNAGSPVKKASKTNTDED- 485 Query: 219 TKMQENFIAMEAEWKDEKQRLLKDIESKDVRISS--LEEANKLLEAARFEISLEHSKLAQ 276 + N A++ KQ LK E++D++ + L++ N L+ + S E+ KL + Sbjct: 486 ---EVNTSALDVTIDSPKQ--LKG-ENEDLKADNQKLKQENDKLKQDSDKTSQENQKLTE 539 Query: 277 ELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLN- 335 ELE L ++S E ++ E SL N + K E +E L Sbjct: 540 ELENLRKQLAE-------LQEKSKEKGSDDSFSQELNSSLNQVNEAIIQSKDEEIEELKG 592 Query: 336 ----------CQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTAS-KMKS 384 Q++Q N++L+ + + + S+ SP+ + K+ +++ K+ + Sbjct: 593 KLAELNGLFEAQVKQ-NEDLQAENTKLTQALEMFSNNDTSSSPVSAAKNFKHSLDEKIAN 651 Query: 385 PWSQLS-----SETLNQDTDKKINK--NEIAKLEMVIQSLN--KDLVD-KEYVISEKDTX 434 ++ ++ L D D+K N + E + +N K +D K+ I Sbjct: 652 LQDAVNKYREITDNLQNDNDEKAELIVNMEKEAEAFAERINHYKSEIDSKDSEIERLKAE 711 Query: 435 XXXXXXXXXGKDTLIAQL--QLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDE 492 K+T Q+ Q+ Q+ + N +IA +Q++L+ + N + Sbjct: 712 IDKLKGELAAKNTEAEQIKGQISDLQYKLSANGQMQEENNSLAKQIADLQKELENKAN-Q 770 Query: 493 IKDVNVK--------DLIEK-LKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKT 543 IKD+ + +L +K + + ++Q + +++ D N + K++S ++ K K++ + Sbjct: 771 IKDLESRLNSLNDQNELKQKEIDALKKQFREKSEQFDLLNSEINKLRSENEEKSKEINQ- 829 Query: 544 IDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMI 603 N + + + KEI L E SQ++ L +E + + + +E++ KK I Sbjct: 830 --NKALIEEKTKEIEALKAENAQKSQQINALSQENEQKKKQIDNLS----VENEQKKKQI 883 Query: 604 EMENLA-ETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSV 662 + ++ E + K I L + +++ L +K ++ E ++ ++S+ Q++Q +I ++ Sbjct: 884 DNLSVENEQKKKQIDNLSEENKLNKKQIDDLAEKNEQNEKQINNLSE-QNEQKKKQIDNL 942 Query: 663 HLEE-----QIDALSASKK-----------ELALVIENLKLDKEQLYGT-IKDLENDKED 705 E QID LS K E+ V+ + ++ +L + D K+D Sbjct: 943 SEENKQNKRQIDDLSEENKLGKEKMNKIESEIRKVVNDTEMTPVRLTSKFVADANEKKKD 1002 Query: 706 IMNKLQNY--IQENMD-LTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDL 762 L+ + + +D L KL+++ EK EL+++ +Q K + I +K+ E Sbjct: 1003 NAKLLEENKALSKAIDELQQKLDELHKEK-DELISQAQKNQQEKEEFGQFIKSKLAEYAD 1061 Query: 763 YIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQL---------GSYLQEKQKAY 813 +++++ E + I L ++I M RR +E+ + L+++ + Sbjct: 1062 NLKSLDKERKEKDQEINALNDTIEAM--RRQEIEQASHHYKDMSDLHNTNKSLEKQIEEM 1119 Query: 814 SEYTIQEDELVNRLAVLMDHDRVVEKQLLEI---EHENKELQKKNQILLEENQNLQISLS 870 E +DE V RL L + +R + L I E EN+EL+K+N+ L E+ + LQ + Sbjct: 1120 KEKVTNDDEEV-RLQ-LQNKEREITASKLMITNKEKENEELKKQNEELKEKTEKLQKEVQ 1177 Query: 871 DMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEI 930 + + N+L + + E E K + +D E N + E Q L + +K +L+ Sbjct: 1178 EKEGEVNSL-KLTFTMNTQELEKQKKEFAAKDTEIN--NLNQEIQKLNQEAEKVTSELQ- 1233 Query: 931 EFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQ-LQEYKNNIENLNMNVEELNKMNLELI 989 ++ S ++ KV E +K + Q A+ +Q+ +++I N+ ++ L K ++E Sbjct: 1234 ----KVTSDLQ--KVTEENAKKQEQEEDQSSAEKIQDLQSDIFNMKREIKTL-KDDIENK 1286 Query: 990 DKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESK 1049 +K +QK S D T + E+NKL + + D+E L + ++ ++ ++ Sbjct: 1287 EKEIQK----SKDETSKINEELNKLKSDKSKLDKENRTLKDQFEKQKILVSALQE--QNN 1340 Query: 1050 LAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQ----ILVREQDDQIKELKETKLTFEMN 1105 ++F + +N++ ++ + +Q N E Q IL E + + +++ E Sbjct: 1341 QSKFEEENKNLKTQLSAAKSEKSKLQQENTEKQNQIDILTAETERKSNQIRSHLTEIEQL 1400 Query: 1106 IPKTEGMIIS----STIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQS 1161 K +G S T + S+ N+ K + + + + +E Sbjct: 1401 KSKLDGQTNSLNDLKTYKQQSEQFNSKLDELQKNLAKAMKEKEEIQTQLTESNKEKEEMQ 1460 Query: 1162 AKLNT------ELQECYTK-IIQLETLNTELTGHDVVNQEQINQLKSKLE---QLNTEND 1211 KL+ ELQ+ Y + + + E L N+E +L +++ +L+ Sbjct: 1461 QKLDDGFRQFEELQDSYNQGMSKYEELEQSYNQGMAQNEELKKKLNDEIKDNKELDKNMH 1520 Query: 1212 NLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQ-READFQKTEH---ELRVQLSAFESK 1267 L+ST E+ + + +A QR + E KQ + +D ++ + EL + ++ +S+ Sbjct: 1521 ELMSTNYEIDTQLKAA-KQRIVSLEEEMKQFQSNDHSSDLEQLKSKLIELTKENNSIKSR 1579 Query: 1268 YEQLLD---SVQSSTQE---ETNKIVT-MEQVTSLQNKLQDKEEHL----RNLQEKYADV 1316 E L++ SV+S E E N I + + ++ + +K + + + L +L+ + + Sbjct: 1580 NEDLIEENKSVKSKVDELSKENNSIKSKVNELNNENSKSKSRIDELIKANDSLKSQLQER 1639 Query: 1317 INQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTE-NQSYKQMQE--QSILNINEE 1373 N+IEI++SE+ ++ L++E S KQ E +++ N+ E Sbjct: 1640 ANEIEIIKSELAEKS--------KEKETENDEIKKLKSELKDSQKQCDELHRNLHNLMNE 1691 Query: 1374 NAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDE 1433 N +LK + D E +L + LE ++ QK + T +ND Sbjct: 1692 NGELKSQNSQLS----------KDFETNNKKLLN-LENAKKQLEQKLADNT---KSQNDM 1737 Query: 1434 FENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNV 1493 F N ++Q+ ++I L E+++EL +L +N N+ E M+ + E E+ +L+ E N Sbjct: 1738 FANYQEQIEALGQKIISLE-EEDAELN-RQLNELKNENNKEEMENK-EKEKDELLAEKNR 1794 Query: 1494 KITESVS-LNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRA-SS 1551 KI E+ N+Q+ LN+ ++E + ++E + EN E L ++ +L +++ + Sbjct: 1795 KIDEAEKEFNEQIKHLNEQIQELIEDSHEKENNNENLAKENSELIQKLNSLHEEIKSLKA 1854 Query: 1552 SKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDLAMYMLHQRD 1600 S + + V + + + Q D + E + + +L+ + Q+D Sbjct: 1855 SNVSQKVELDQNKEYIQKRQKDIDLLNEEYNNLFNEKLEFEFEINSQKD 1903 Score = 153 bits (372), Expect = 3e-35 Identities = 329/1514 (21%), Positives = 620/1514 (40%), Gaps = 157/1514 (10%) Query: 154 KDNALSVLQVKMKIMETTILDLQEKINEKDQIIEA--------KNKAT-TXXXXXXXXXX 204 K+ ALS + +E+ +L +KI EKD +I + ++KA Sbjct: 26 KEKALSGALKENLALESKNAELAQKIKEKDILIRSLQEENYKYRSKANQVSREQANEEKI 85 Query: 205 XXXXXXXEDTKQQMTKMQENFIAMEA----EWKDEKQRLLKDIESKDVRISSLEEANKL- 259 + Q T + ++ +A + + + ++L ++E+ +V++ + + K Sbjct: 86 SQLGLKFQKQLNQKTLQYASQLSAQAKSISDLEAQVKKLNTELENTEVKLQTASKKQKAK 145 Query: 260 LEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIA 319 L+A E + L + + Q +Q I+ S E+ + ++ LE Sbjct: 146 LQATIKEKQAQIDTLNERIAQDSILYEESAKQLESY-QQQIQ-SLNEEIKSKDVSILERD 203 Query: 320 N-MTELTKKI-ELLEHLNCQIRQTN---KELENKLATMGTESK-----AVSSPSKKGSPL 369 N + EL KI +++ ++ + +Q+ E E +A + + K A + K S Sbjct: 204 NTIRELENKINDIVGKVDQKFKQSKDAIAEKEKIVAQLKKDPKNEGIVAAIEKADKSSSQ 263 Query: 370 ISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIA-KLEMVIQSLNKDLVDKEYVI 428 ++ KS + SE D INKN+ A +L +IQ+ + + + E + Sbjct: 264 LNESVNELQEKLSKSQINGDESEVSASQLDISINKNDSASELCEIIQNKDNRIKELEAAV 323 Query: 429 SEKDTXXXXXXXXXXGKDTLIAQLQLE-HQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQ 487 E Q Q+E H+Q +E + E ++ E+ + Sbjct: 324 EELKHKPMKMNDIAQNSQENALQSQIEIHEQEIEELQATNQALEKEIEILNQRLAEKSDK 383 Query: 488 ELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNM--IKVKSNHKLKLKQMQKTID 545 LN+ I + K+L + L E Q TQ+ND NK + K + + ++ +Q T++ Sbjct: 384 TLNERISYLE-KELSKTLSENETQKTQINDFTSRINKYKAELDAKVDQEAQILTLQ-TLN 441 Query: 546 NFSKVSDSN--KEIVRLTEEL-HHLSQKV---------AELEEEKGNLQLHLVDYDSGRM 593 K S +N KEI L L LS +E++ N V DS + Sbjct: 442 TELKESLANKDKEIADLKALLDKDLSSNAGSPVKKASKTNTDEDEVNTSALDVTIDSPKQ 501 Query: 594 IESDVYKKMIEMENLAE--TRLKAISLLESQKFD-LVQELHILQQKYDEVEDKLADISQL 650 ++ + + + L + +LK S SQ+ L +EL L+++ E+++K + Sbjct: 502 LKGENEDLKADNQKLKQENDKLKQDSDKTSQENQKLTEELENLRKQLAELQEK---SKEK 558 Query: 651 QSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIM--- 707 SD S+ + L + +A+ SK E IE LK +L G + ED+ Sbjct: 559 GSDDSFSQELNSSLNQVNEAIIQSKDE---EIEELKGKLAELNGLFEAQVKQNEDLQAEN 615 Query: 708 NKLQNYIQENMDLTDKLEKMSAEK-----ISELLAKINHEEQSKIQTQFGIDAKIQERDL 762 KL ++ + +SA K + E +A + + + E+ Sbjct: 616 TKLTQALEMFSNNDTSSSPVSAAKNFKHSLDEKIANLQDAVNKYREITDNLQNDNDEKAE 675 Query: 763 YIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDE 822 I N+E E + RI + I + L+ + D+L L K + Q + Sbjct: 676 LIVNMEKEAEAFAERINHYKSEIDSKDSEIERLKAEIDKLKGELAAKNTEAEQIKGQISD 735 Query: 823 LVNRLAV---LMDHDRVVEKQL--LEIEHEN-----KELQKKNQILLEENQNLQISLSDM 872 L +L+ + + + + KQ+ L+ E EN K+L+ + L ++N+ Q + + Sbjct: 736 LQYKLSANGQMQEENNSLAKQIADLQKELENKANQIKDLESRLNSLNDQNELKQKEIDAL 795 Query: 873 QQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEF 932 ++ + EK+ + DL SE K ++ + E K I ++++ LI +K KEIE L+ E Sbjct: 796 KKQFR---EKSEQFDLLNSEINKLRS---ENEEKSKEI-NQNKALIEEKTKEIEALKAE- 847 Query: 933 NTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNM----------NVEELN 982 N Q I NE+ +K I+ L + ++ K I+NL++ N+ E N Sbjct: 848 NAQKSQQINALSQENEQKKKQID---NLSVENEQKKKQIDNLSVENEQKKKQIDNLSEEN 904 Query: 983 KMNLELID------KHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALN------- 1029 K+N + ID + +KQ + EQ +I+ L+ KQ +I L+ Sbjct: 905 KLNKKQIDDLAEKNEQNEKQINNLSEQNEQKKKQIDNLSEENKQNKRQIDDLSEENKLGK 964 Query: 1030 QKINNAQVSYMSMVSDYESKLAQFTTK-LENMEEEMQRVSKQLLDSKQHNEELQILVREQ 1088 +K+N + +V+D E + T+K + + E+ + +K L ++K ++ + L ++ Sbjct: 965 EKMNKIESEIRKVVNDTEMTPVRLTSKFVADANEKKKDNAKLLEENKALSKAIDELQQKL 1024 Query: 1089 DDQIKELKETKLTFEMNIPKTE--GMIISSTIEPMSDDANNVDXXXXXXXXXXXXL---- 1142 D+ KE E + N + E G I S + +D+ ++D L Sbjct: 1025 DELHKEKDELISQAQKNQQEKEEFGQFIKSKLAEYADNLKSLDKERKEKDQEINALNDTI 1084 Query: 1143 ------KVQEEEEFIQERSVLQEQSAKLNTELQECYTKI--------IQLETLNTELTGH 1188 ++++ ++ S L + L +++E K+ +QL+ E+T Sbjct: 1085 EAMRRQEIEQASHHYKDMSDLHNTNKSLEKQIEEMKEKVTNDDEEVRLQLQNKEREITAS 1144 Query: 1189 D--VVNQEQIN-QLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQ--HL 1243 + N+E+ N +LK + E+L + + L V E ++S EL KQ Sbjct: 1145 KLMITNKEKENEELKKQNEELKEKTEKLQKEVQEKEGEVNSLKLTFTMNTQELEKQKKEF 1204 Query: 1244 AQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQ---EETNKIVTMEQVTSLQNKLQ 1300 A ++ + E++ +L+ K L V S Q EE K E+ S K+Q Sbjct: 1205 AAKDTEINNLNQEIQ-KLNQEAEKVTSELQKVTSDLQKVTEENAKKQEQEEDQSSAEKIQ 1263 Query: 1301 DKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYK 1360 D + + N++ + + + IE EI+ K L EN++ K Sbjct: 1264 DLQSDIFNMKREIKTLKDDIENKEKEIQKSKDE-TSKINEELNKLKSDKSKLDKENRTLK 1322 Query: 1361 -QMQEQSIL--NINEENAQLK--KSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSE 1415 Q ++Q IL + E+N Q K + + + + + E +Q+++ +E Sbjct: 1323 DQFEKQKILVSALQEQNNQSKFEEENKNLKTQLSAAKSEKSKLQQENTEKQNQIDILTAE 1382 Query: 1416 IYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDL-TYEKESELAILRLKMHENANHYE 1474 +K+++ LT E E ++ +L + DL TY+++SE K+ E + Sbjct: 1383 TERKSNQIRSHLT----EIEQLKSKLDGQTNSLNDLKTYKQQSEQ--FNSKLDELQKNLA 1436 Query: 1475 TMQKESEIERVKLIEELNVKITESVSLN---KQVAELNKALEEEVAKTNEM-----QTAL 1526 KE E + +L E K L+ +Q EL + + ++K E+ Q Sbjct: 1437 KAMKEKEEIQTQLTESNKEKEEMQQKLDDGFRQFEELQDSYNQGMSKYEELEQSYNQGMA 1496 Query: 1527 ENQEIEIVTLNDEI 1540 +N+E++ LNDEI Sbjct: 1497 QNEELK-KKLNDEI 1509 Score = 139 bits (337), Expect = 5e-31 Identities = 225/1180 (19%), Positives = 486/1180 (41%), Gaps = 84/1180 (7%) Query: 215 KQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVR-ISSLEEANKLLEAARFEISLEHSK 273 K + + Q N ++ + E K ++ L + ++ R I L E NKL + +I E K Sbjct: 917 KNEQNEKQINNLSEQNEQKKKQIDNLSEENKQNKRQIDDLSEENKLGKEKMNKIESEIRK 976 Query: 274 LAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTK-KIELLE 332 + + E K+ EE + + + EL K K EL+ Sbjct: 977 VVNDTEMTPVRLTSKFVADANEKKKDNAKLLEENKALSKAIDELQQKLDELHKEKDELIS 1036 Query: 333 HLNCQIRQTNKE-----LENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWS 387 Q Q KE +++KLA K++ K+ I+ + +T M+ Sbjct: 1037 Q--AQKNQQEKEEFGQFIKSKLAEYADNLKSLDKERKEKDQEINALN--DTIEAMRRQEI 1092 Query: 388 QLSSETLNQDTD-KKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKD 446 + +S +D NK+ ++E + + + D + + K+ K+ Sbjct: 1093 EQASHHYKDMSDLHNTNKSLEKQIEEMKEKVTNDDEEVRLQLQNKEREITASKLMITNKE 1152 Query: 447 TLIAQLQLEHQQHMEGPSLIH--VGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEK 504 +L+ ++++ E + V +VN + QEL + K+ KD + Sbjct: 1153 KENEELKKQNEELKEKTEKLQKEVQEKEGEVNSLKLTFTMNTQELEKQKKEFAAKDT--E 1210 Query: 505 LKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEEL 564 + + ++I +LN E + + KV S+ + ++ K + S + K I L ++ Sbjct: 1211 INNLNQEIQKLNQEAEKVTSELQKVTSDLQKVTEENAKKQEQEEDQSSAEK-IQDLQSDI 1269 Query: 565 HHLSQKVAELEEEKGNLQLHLV-DYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQK 623 ++ +++ L+++ N + + D I ++ K + L + E QK Sbjct: 1270 FNMKREIKTLKDDIENKEKEIQKSKDETSKINEELNKLKSDKSKLDKENRTLKDQFEKQK 1329 Query: 624 FDLVQELHIL--QQKYDEVEDKL-ADISQLQSDQVCSEIKSVHLEEQIDALSASKKELAL 680 LV L Q K++E L +S +S++ + ++ + QID L+A + + Sbjct: 1330 I-LVSALQEQNNQSKFEEENKNLKTQLSAAKSEKSKLQQENTEKQNQIDILTAETERKSN 1388 Query: 681 VIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISE---LLA 737 I + + EQL + N D+ Q Q N L D+L+K A+ + E + Sbjct: 1389 QIRSHLTEIEQLKSKLDGQTNSLNDLKTYKQQSEQFNSKL-DELQKNLAKAMKEKEEIQT 1447 Query: 738 KINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLE- 796 ++ + K + Q +D ++ + ++ +SKY+ + +A E+ + L Sbjct: 1448 QLTESNKEKEEMQQKLDDGFRQFEELQDSYNQGMSKYEELEQSYNQGMAQNEELKKKLND 1507 Query: 797 --RKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLM---------DHDRVVEK---QLL 842 + +L + E E Q R+ L DH +E+ +L+ Sbjct: 1508 EIKDNKELDKNMHELMSTNYEIDTQLKAAKQRIVSLEEEMKQFQSNDHSSDLEQLKSKLI 1567 Query: 843 EIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRD 902 E+ EN ++ +N+ L+EEN++++ + ++ + N++ K N + S+S +L Sbjct: 1568 ELTKENNSIKSRNEDLIEENKSVKSKVDELSKENNSIKSKVNELNNENSKSKSRIDELIK 1627 Query: 903 LESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQ------IESAIRDKKVLNEKYEKNIEY 956 +LK E I K E+ + E T+ ++S ++D + ++ +N+ Sbjct: 1628 ANDSLKSQLQERANEIEIIKSELAEKSKEKETENDEIKKLKSELKDSQKQCDELHRNLHN 1687 Query: 957 VT----QLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEIN 1012 + +L++Q + + E N + L +L K ++Q+ D Y +I Sbjct: 1688 LMNENGELKSQNSQLSKDFETNNKKLLNLENAKKQLEQKLADNTKSQN-DMFANYQEQIE 1746 Query: 1013 KLNALLKQKDEEIIALNQKIN-----NAQVSYMSMVSDYESKLAQFTTKLENMEEEM--- 1064 L + +EE LN+++N N + + + + LA+ K++ E+E Sbjct: 1747 ALGQKIISLEEEDAELNRQLNELKNENNKEEMENKEKEKDELLAEKNRKIDEAEKEFNEQ 1806 Query: 1065 -----QRVSKQLLDSKQHNEELQILVREQDDQIKEL----KETKLTFEMNIPKTEGMIIS 1115 +++ + + DS + + L +E + I++L +E K N+ ++ + + Sbjct: 1807 IKHLNEQIQELIEDSHEKENNNENLAKENSELIQKLNSLHEEIKSLKASNV--SQKVELD 1864 Query: 1116 STIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKI 1175 E + ++D K++ E E ++ L +S +N + E I Sbjct: 1865 QNKEYIQKRQKDIDLLNEEYNNLFNE-KLEFEFEINSQKDELNNKSQYINNQKNE----I 1919 Query: 1176 IQLETLNTELTGHDVVNQEQINQLKSKLEQ---LNTENDNLLSTVAELRSSISSAVDQRG 1232 L+ N E Q++I+ + K+++ LN E +N L+ +A+ + D Sbjct: 1920 DNLKKQNNEKQNEIAKLQKEIDSYQEKIDKLISLNEEKNNKLTNLAKQQQYAQKNRDLEL 1979 Query: 1233 FEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQ-SSTQEETNKIVTMEQ 1291 + E L Q A Q+ ++L + + + E++L ++ +S+ + N++++ ++ Sbjct: 1980 NDGNENEISELRQNNAKLQRKCNKLVEEKAQLAEQLEKVLTLMKNNSSNPQGNQVLSNDE 2039 Query: 1292 VTSL----QNKLQDKEEHLRNLQEKYADVINQIEILRSEI 1327 +TSL Q+++ ++E+ +L Y +VI +++ +++ Sbjct: 2040 LTSLLKQKQSEVSEREKQFNSLLILYDNVIKELKEANAKV 2079 Score = 135 bits (326), Expect = 1e-29 Identities = 262/1387 (18%), Positives = 587/1387 (42%), Gaps = 115/1387 (8%) Query: 233 KDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXX 292 + + L + I+ KD+ I SL+E N + ++S E + +++ Q Sbjct: 41 ESKNAELAQKIKEKDILIRSLQEENYKYRSKANQVSREQAN-EEKISQ----------LG 89 Query: 293 XXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIEL-LEHLNCQIRQTNKELENKL-A 350 KQ + + + +++ + I+++ KK+ LE+ +++ +K+ + KL A Sbjct: 90 LKFQKQLNQKTLQYASQLSAQAK-SISDLEAQVKKLNTELENTEVKLQTASKKQKAKLQA 148 Query: 351 TMGTESKAVSSPSKKGSPLISRKS--GRNTASKMKSPWSQLSSETLNQDTDKKINKNEIA 408 T+ + + + +++ I++ S +A +++S Q+ S LN++ K I Sbjct: 149 TIKEKQAQIDTLNER----IAQDSILYEESAKQLESYQQQIQS--LNEEIKSK--DVSIL 200 Query: 409 KLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHV 468 + + I+ L + D ++ + D K+ ++AQL+ + + ++ Sbjct: 201 ERDNTIRELENKIND---IVGKVDQKFKQSKDAIAEKEKIVAQLKKDPKNEGIVAAIEKA 257 Query: 469 GTNTEDVNE-IAKVQEQL-KQELNDEIKDVNVKDL---IEKLKSAEE--QITQLND---- 517 ++ +NE + ++QE+L K ++N + +V+ L I K SA E +I Q D Sbjct: 258 DKSSSQLNESVNELQEKLSKSQINGDESEVSASQLDISINKNDSASELCEIIQNKDNRIK 317 Query: 518 EIDAANKNM-IKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLT-----EELHHLSQKV 571 E++AA + + K + + + + + ++ + E ++ T +E+ L+Q++ Sbjct: 318 ELEAAVEELKHKPMKMNDIAQNSQENALQSQIEIHEQEIEELQATNQALEKEIEILNQRL 377 Query: 572 AELEEEKGNLQLHLVDYD-SGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQEL 630 AE ++ N ++ ++ + S + E++ K I N +R+ K D ++ Sbjct: 378 AEKSDKTLNERISYLEKELSKTLSENETQKTQI---NDFTSRINKYKAELDAKVDQEAQI 434 Query: 631 HILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSAS--KKELALVIENLKLD 688 LQ E+++ LA+ D+ +++K++ L++ + + + S KK + +++ Sbjct: 435 LTLQTLNTELKESLAN-----KDKEIADLKAL-LDKDLSSNAGSPVKKASKTNTDEDEVN 488 Query: 689 KEQLYGTI---KDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQS 745 L TI K L+ + ED+ Q QEN DKL K ++K S+ K+ EE Sbjct: 489 TSALDVTIDSPKQLKGENEDLKADNQKLKQEN----DKL-KQDSDKTSQENQKLT-EELE 542 Query: 746 KIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRY-SLERKADQLGS 804 ++ Q A++QE+ + +S + S + ++ E+I +D L+ K +L Sbjct: 543 NLRKQL---AELQEKSKEKGSDDSFSQELNSSLNQVNEAIIQSKDEEIEELKGKLAELNG 599 Query: 805 YLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVE--KQLLEIEHENKELQKKNQILLEEN 862 + + K + + +L L + ++D +H E Q + + Sbjct: 600 LFEAQVKQNEDLQAENTKLTQALEMFSNNDTSSSPVSAAKNFKHSLDEKIANLQDAVNKY 659 Query: 863 QNLQISL-SDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTL---I 918 + + +L +D + +V + Y++++ +S ++R+ E L + Sbjct: 660 REITDNLQNDNDEKAELIVNMEKEAEAFAERINHYKSEIDSKDSEIERLKAEIDKLKGEL 719 Query: 919 VQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNV 978 K E E ++ + + ++ + + E+ + + L+ +L+ N I++L + Sbjct: 720 AAKNTEAEQIKGQI-SDLQYKLSANGQMQEENNSLAKQIADLQKELENKANQIKDLESRL 778 Query: 979 EELNKMNLELIDKHVQKQQTQSPDYTEQY--IN-EINKLNALLKQKDEEIIALNQKINNA 1035 LN N EL K + + Q + +EQ+ +N EINKL + ++K +EI I Sbjct: 779 NSLNDQN-ELKQKEIDALKKQFREKSEQFDLLNSEINKLRSENEEKSKEINQNKALIEEK 837 Query: 1036 QVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKEL 1095 ++ ++ K Q + E++ +++ ++++Q +++ L E + + K++ Sbjct: 838 TKEIEALKAENAQKSQQINALSQENEQKKKQIDNLSVENEQKKKQIDNLSVENEQKKKQI 897 Query: 1096 KETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERS 1155 L+ E + K + ++ E NN+ L +E ++ ++ Sbjct: 898 --DNLSEENKLNKKQIDDLAEKNEQNEKQINNLSEQNEQKKKQIDNLS-EENKQNKRQID 954 Query: 1156 VLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLS 1215 L E++ KL E I+ +TE+T + ++ + + +N LL Sbjct: 955 DLSEEN-KLGKEKMNKIESEIRKVVNDTEMTPVRLT-----SKFVADANEKKKDNAKLL- 1007 Query: 1216 TVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSV 1275 E ++S A+D+ ++ EL K+ + + QK + E +SK + D++ Sbjct: 1008 ---EENKALSKAIDELQQKLDELHKEK-DELISQAQKNQQEKEEFGQFIKSKLAEYADNL 1063 Query: 1276 QSSTQEETNKIVTMEQVTSLQNKLQDKE-EHLRNLQEKYADVINQIEILRSEIEDEKVAF 1334 +S +E K + + ++ +E E + + +D+ N + L +IE+ K Sbjct: 1064 KSLDKERKEKDQEINALNDTIEAMRRQEIEQASHHYKDMSDLHNTNKSLEKQIEEMK--- 1120 Query: 1335 XXXXXXXXXXXXXXXXDLRTENQSYK-QMQEQSILNINEENAQLKKSSXXXXXXXXXXXX 1393 L+ +N+ + + I N +EN +LKK + Sbjct: 1121 ------EKVTNDDEEVRLQLQNKEREITASKLMITNKEKENEELKKQNEELKEKTEKLQK 1174 Query: 1394 RVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTY 1453 V + E +V L + E+ ++ E+ ++ E N+ Q++ + + E +T Sbjct: 1175 EVQEKEGEVNSLKLTFTMNTQELEKQKKEF----AAKDTEINNLNQEIQKLNQEAEKVTS 1230 Query: 1454 EKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALE 1513 E + + L+ ENA E + +S E+++ ++ + + K E NK E Sbjct: 1231 ELQKVTSDLQKVTEENAKKQEQEEDQSSAEKIQDLQSDIFNMKREIKTLKDDIE-NK--E 1287 Query: 1514 EEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLD 1573 +E+ K+ + +T+ N+E+ L + + L R + +K S ++ ++ Sbjct: 1288 KEIQKSKD-ETSKINEELN--KLKSDKSKLDKENRTLKDQFEKQKILVSALQEQNNQSKF 1344 Query: 1574 NTMNKEL 1580 NK L Sbjct: 1345 EEENKNL 1351 Score = 80.6 bits (190), Expect = 3e-13 Identities = 151/773 (19%), Positives = 301/773 (38%), Gaps = 73/773 (9%) Query: 836 VVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTK 895 V EK L EN L+ KN L ++ + I + +Q+ KAN+ ++ K Sbjct: 25 VKEKALSGALKENLALESKNAELAQKIKEKDILIRSLQEENYKYRSKANQVSREQANEEK 84 Query: 896 YQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIE---FNTQIE--------------- 937 + L + T ++ + + + K I DLE + NT++E Sbjct: 85 ISQLGLKFQKQLNQKTLQYASQLSAQAKSISDLEAQVKKLNTELENTEVKLQTASKKQKA 144 Query: 938 ---SAIRDKK----VLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELID 990 + I++K+ LNE+ ++ + QL+ Y+ I++LN ++ + LE D Sbjct: 145 KLQATIKEKQAQIDTLNERIAQDSILYEESAKQLESYQQQIQSLNEEIKSKDVSILER-D 203 Query: 991 KHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKL 1050 +++ + + D + + + + +K++ + L + N + ++ + + Sbjct: 204 NTIRELENKINDIVGKVDQKFKQSKDAIAEKEKIVAQLKKDPKNEGI--VAAIEKADKSS 261 Query: 1051 AQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTE 1110 +Q + ++E++ + +S+ +L I + ++D EL E + I + E Sbjct: 262 SQLNESVNELQEKLSKSQINGDESEVSASQLDISI-NKNDSASELCEIIQNKDNRIKELE 320 Query: 1111 GMIISSTIEP--MSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTEL 1168 + +P M+D A N + QE EE L+++ LN L Sbjct: 321 AAVEELKHKPMKMNDIAQN---SQENALQSQIEIHEQEIEELQATNQALEKEIEILNQRL 377 Query: 1169 QECYTKII--QLETLNTELT---GHDVVNQEQINQLKSKLEQLNTENDNLLS------TV 1217 E K + ++ L EL+ + + QIN S++ + E D + T+ Sbjct: 378 AEKSDKTLNERISYLEKELSKTLSENETQKTQINDFTSRINKYKAELDAKVDQEAQILTL 437 Query: 1218 AELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQS 1277 L + + ++ + EIA+L A + D + S + +++ S Sbjct: 438 QTLNTELKESLANKDKEIADL----KALLDKDLSSNAGSPVKKASKTNTDEDEVNTSALD 493 Query: 1278 STQEETNKIV-TMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXX 1336 T + ++ E + + KL+ + + L+ +K + + + L E+E+ + Sbjct: 494 VTIDSPKQLKGENEDLKADNQKLKQENDKLKQDSDKTS---QENQKLTEELENLRKQLAE 550 Query: 1337 XXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVN 1396 + N S Q+ E I + +EE +LK + Sbjct: 551 LQEKSKEKGSDDSFS-QELNSSLNQVNEAIIQSKDEEIEELKGKLAELNGLFEAQVKQNE 609 Query: 1397 DAEAKVLELTHQLEL-KDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEK 1455 D +A+ +LT LE+ +++ DE Q V + I D Sbjct: 610 DLQAENTKLTQALEMFSNNDTSSSPVSAAKNFKHSLDEKIANLQDAVNKYREITDNLQND 669 Query: 1456 ESELAILRLKMHENA-------NHY--ETMQKESEIERV-----KLIEELNVKITESVSL 1501 E A L + M + A NHY E K+SEIER+ KL EL K TE+ + Sbjct: 670 NDEKAELIVNMEKEAEAFAERINHYKSEIDSKDSEIERLKAEIDKLKGELAAKNTEAEQI 729 Query: 1502 NKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKI 1554 Q+++ L+ +++ +MQ + +I L E+ N N ++ S++ Sbjct: 730 KGQISD----LQYKLSANGQMQEENNSLAKQIADLQKELENKANQIKDLESRL 778 Score = 80.6 bits (190), Expect = 3e-13 Identities = 107/556 (19%), Positives = 247/556 (44%), Gaps = 57/556 (10%) Query: 319 ANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNT 378 + + ELTK+ ++ N + + NK +++K+ + E+ ++ S ++ + N+ Sbjct: 1564 SKLIELTKENNSIKSRNEDLIEENKSVKSKVDELSKENNSIKSK-------VNELNNENS 1616 Query: 379 ASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEY--VISE-KDTXX 435 SK + ++++L ++ N+ EI K E+ +S K+ + E + SE KD+ Sbjct: 1617 KSKSRIDELIKANDSLKSQLQERANEIEIIKSELAEKSKEKETENDEIKKLKSELKDSQK 1676 Query: 436 XXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKD 495 + + +L+ Q TN + + + ++QL+Q+L D K Sbjct: 1677 QCDELHRNLHNLMNENGELKSQNSQLSKDF---ETNNKKLLNLENAKKQLEQKLADNTKS 1733 Query: 496 VN--VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKS-NHKLKLKQMQKTIDNF----- 547 N + E++++ ++I L +E N+ + ++K+ N+K +++ +K D Sbjct: 1734 QNDMFANYQEQIEALGQKIISLEEEDAELNRQLNELKNENNKEEMENKEKEKDELLAEKN 1793 Query: 548 SKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMEN 607 K+ ++ KE E++ HL++++ EL E+ H + ++ + + + ++I+ N Sbjct: 1794 RKIDEAEKEF---NEQIKHLNEQIQELIEDS-----HEKENNNENLAKEN--SELIQKLN 1843 Query: 608 LAETRLKAISLLE-SQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEE 666 +K++ SQK +L Q +Q++ +++ + + L ++++ E + ++ Sbjct: 1844 SLHEEIKSLKASNVSQKVELDQNKEYIQKRQKDIDLLNEEYNNLFNEKLEFEFEINSQKD 1903 Query: 667 QIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEK 726 +++ S I+NLK + I L+ + + K+ I N + +KL Sbjct: 1904 ELNNKSQYINNQKNEIDNLKKQNNEKQNEIAKLQKEIDSYQEKIDKLISLNEEKNNKLTN 1963 Query: 727 MS-----AEKISELLAKINHEE------QSKIQTQFGIDAKIQERDLYIENIESELSKYK 775 ++ A+K +L +E Q+ + Q + ++E+ E +E L+ K Sbjct: 1964 LAKQQQYAQKNRDLELNDGNENEISELRQNNAKLQRKCNKLVEEKAQLAEQLEKVLTLMK 2023 Query: 776 SRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRL-------- 827 + + + + D SL + Q S + E++K ++ I D ++ L Sbjct: 2024 NNSSNPQGNQVLSNDELTSLLK---QKQSEVSEREKQFNSLLILYDNVIKELKEANAKVA 2080 Query: 828 ---AVLMDHDRVVEKQ 840 A ++H R+VEK+ Sbjct: 2081 RLEAAAVNHARIVEKR 2096 >UniRef50_A2FKT9 Cluster: Viral A-type inclusion protein, putative; n=1; Trichomonas vaginalis G3|Rep: Viral A-type inclusion protein, putative - Trichomonas vaginalis G3 Length = 2114 Score = 174 bits (424), Expect = 1e-41 Identities = 280/1374 (20%), Positives = 610/1374 (44%), Gaps = 136/1374 (9%) Query: 220 KMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHS-KLAQEL 278 K + F ++ +++D ++L D + +++ +L+ N L +I +++ A++ Sbjct: 770 KFKNEFEFIKKQYEDNI-KVLNDRQQEEIDQLNLQNKNMLNVLKNEKIIVQNQLNEARQR 828 Query: 279 EQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIEL-LEHLNCQ 337 + + I+ E++ E E+K S N L + + +E L + Sbjct: 829 VKDLEDKNQILLDQKQTREDGIDRIEEKQREYEDKISSLEQNFDHLNLEHQKDMEKLQAE 888 Query: 338 IRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQD 397 I++ E + + M + + + KK + +IS RN+ + K+ L Q+ Sbjct: 889 IKKLESEKQQLINKMMNDHNS-NKDQKKMNEIISDLQKRNSEIEQKNQ----EINQLKQE 943 Query: 398 TDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQ 457 D++ K ++ L+ + K+ ++ E +IS+ + + + + Sbjct: 944 IDQE--KEKVTNLDTEKSKMQKEKINMEQIISQNEQEKKELQQVITEYEQSLNDFNINSI 1001 Query: 458 QHMEGPSLIH--VGTNTEDVNEIAKVQEQLKQELNDEIKDVNVK--DLIEKLKSAEEQIT 513 + E + + + +++ + + + K++ +EI +N K DL + K EQI Sbjct: 1002 KQKEQIKTLQNQIQSLNSEISNFNEKENEEKEKHKNEIDKLNQKLNDLQNQRKILHEQI- 1060 Query: 514 QLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNF-SKVS----DSNKEIVRLTEELHHLS 568 L +E N I+ K N +L+ K+ +KTI++F +K+ +S+++I + +E+ + Sbjct: 1061 DLQNEHHKKEMNDIQSKIN-ELE-KEKKKTIEDFQNKIKNIQEESDRKIKQNMDEIESKN 1118 Query: 569 QKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQ 628 +K+ +LE+E+ N Q + SD Y++++ NL +L + Q +L+ Sbjct: 1119 KKIQDLEQERNNQQKMIEKLAKDN---SDEYEEVV---NLFNQQLDNLRQNNRQNENLIA 1172 Query: 629 ELHIL-QQKYDEVEDKLADISQLQSDQVCSEIKSVH---LEEQIDALSASKKELALVIEN 684 L ++K E+E + +IS+LQ SEIK+ + E ++ +K+++A I++ Sbjct: 1173 SLRSSNEEKQKEIEKLVQEISELQKQ--ISEIKNQNDFETERLLNESKEAKQKMASKIKD 1230 Query: 685 LKLDKEQLYGTIKDLENDKEDI----MNKLQNYIQENMDLTDKLEKMSAEKISELLAKIN 740 L+ DK+ L I+ L+ +++ M++ +++ +E ++K+++++ E+I +L +IN Sbjct: 1231 LESDKKFLQQEIEKLKRINDNLNQQNMSQKRDFDEELSQKSNKIKELN-ERIIDLQKQIN 1289 Query: 741 HEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKAD 800 +++ S++ ++ +Q++ ++ + EL KS L++ I+ + R L+++AD Sbjct: 1290 NDDLSQLNSRLH---NLQKQKDEVDQLNIELKNDKSN---LQKQISSLAKEREDLKQQAD 1343 Query: 801 QLGSYLQ-------EKQKAYSEYTIQEDELVNRL-AVLMDHDRVV---EKQLLEIEHENK 849 L Y + EK+ E ++ N+ +D ++ +KQL +++ + Sbjct: 1344 SLNDYKKRVSDLEKEKENLVQNIKNMEIQISNQKDGNQPKNDALITALQKQLESMKNRRE 1403 Query: 850 ELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKR 909 ++K L +NQ L ++++ L+ K +L E K++TQ R L +L++ Sbjct: 1404 NIEKD---LKAQNQQLVDKNKELEEKVQELMHKITELNL---ELCKFKTQQRQLNRDLEK 1457 Query: 910 ITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKN 969 I E++ L K D E+ + +IE + +N K IE +++ EA + +N Sbjct: 1458 IQQENEKL----KNAKTDSELNSSKRIEFLENQLENVN----KQIEELSKAEAN--KIQN 1507 Query: 970 NIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEIN-KLNALLKQK---DEEI 1025 ++ N E+L K EL +K + Q +NE+ K+ L K+K D++I Sbjct: 1508 QLDMKNKENEQLQKEKQELAEK-INNLQI--------ILNELQIKIEILEKEKSDLDKQI 1558 Query: 1026 IALNQKINNAQVSYMSM---VSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQ 1082 LN+ +NN++ + + +++ + ++L ++ + K + + Q N+EL Sbjct: 1559 EKLNEDLNNSESKNKEIERQIFQLQNRKSDVNSQLNTLQVDKDYYQKIIDELHQKNDELV 1618 Query: 1083 ILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXL 1142 ++ DQ+ EL + K ++N + + + ++ + D L Sbjct: 1619 QRIKVLVDQLNELLKVK--DQLNGSNEDLLKKITELQGLKDQLEE------------NYL 1664 Query: 1143 KVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSK 1202 K++++ + I E ++EQ +N L+E +I +LE + + E+I+ K Sbjct: 1665 KLKDDNQTISE---MKEQLDDVNELLKE---RISELEGIQES----NESKIEEISNELDK 1714 Query: 1203 LEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLS 1262 + + T+ +NL T + S S + +R + E K+ L + + Q+ EL+ + Sbjct: 1715 YKSMTTDLNNL--TEIDNISIDGSGIKERNDSLNEKIKE-LQDKIDELQRNYDELQSLHT 1771 Query: 1263 AFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEI 1322 + + ++ DS + + + + KL E L L + + D++ Sbjct: 1772 QVKDENSRIKDSYNELNASKEKLQINFDNLDQNNKKL---ESDLDKLNKSFNDLLEN--- 1825 Query: 1323 LRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSX 1382 +++D D++ N++ Q+ E + + N L + Sbjct: 1826 -NQQLQDNNNQLNEEKNKLQSDFDNSQNDIKKFNENINQLCESNN-KLENANKDLNERQK 1883 Query: 1383 XXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVR---Q 1439 +V + ++ +L + E D E E I Q +DE + + Q Sbjct: 1884 ILERDNNELKRQVENLMGEINKLNEEKENLDRERKSLEGEL-IKQNQNDDEIKRLNDEIQ 1942 Query: 1440 QLVEYEKRIEDLTYEKESELAILR--LKMHENANHYETMQKESEIERVK-------LIEE 1490 L ++K +E+ KE++L+ L L NA + + + +IE +K LIE+ Sbjct: 1943 SLNHHKKELEENLKLKENQLSDLSNTLSTISNALNSQISGLKEQIEELKQKQNPNELIEK 2002 Query: 1491 LNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQ 1544 LN E L + + + +K EE + +E++ +N EI LN + +L+ Sbjct: 2003 LNELQEEKKKLEQDITDKDKLNEELQKRVDELEKEKQNHYEEIQQLNLKTRDLE 2056 Score = 167 bits (407), Expect = 2e-39 Identities = 261/1248 (20%), Positives = 530/1248 (42%), Gaps = 106/1248 (8%) Query: 411 EMVIQSLNKDL--VDKEY--VISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLI 466 EM ++ LN L +DK+ + SE D+ + I++L+ + + + + + Sbjct: 604 EMEVEMLNNQLSMIDKQRQNLQSELDSVNHKHYETTNMLNDKISKLESDKKSYQDKYESL 663 Query: 467 HVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNM 526 + ++ K E+ ++L + D N++DL + K + +L +E K+ Sbjct: 664 SKELDY-NIENARKEYEEKTKDLR-RLYDKNIQDLSDLQKGKQILERKLEEE---EKKHE 718 Query: 527 IKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKV-AELEEE-KGNLQLH 584 + + +++++ ++ ++ K I +EL Q V ++ E+ K + Sbjct: 719 EEREWERNKSQEEIKRGLNRIIELESQQKRIYIENDELKERLQTVYIDVSEKFKNEFEFI 778 Query: 585 LVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDK- 643 Y+ + +D ++ I+ NL + +++L+++K + +L+ +Q+ ++EDK Sbjct: 779 KKQYEDNIKVLNDRQQEEIDQLNLQNKNM--LNVLKNEKIIVQNQLNEARQRVKDLEDKN 836 Query: 644 --LADISQLQSDQVCS-EIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLE 700 L D Q + D + E K E++I +L + L L E+ K D E+L IK LE Sbjct: 837 QILLDQKQTREDGIDRIEEKQREYEDKISSLEQNFDHLNL--EHQK-DMEKLQAEIKKLE 893 Query: 701 NDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQER 760 ++K+ ++NK+ N N D +K E IS+L K N E + K Q + +I + Sbjct: 894 SEKQQLINKMMNDHNSNKD-----QKKMNEIISDL-QKRNSEIEQKNQEINQLKQEIDQE 947 Query: 761 DLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQE 820 + N+++E SK + +E+ I+ E + L++ + L + + Q Sbjct: 948 KEKVTNLDTEKSKMQKEKINMEQIISQNEQEKKELQQVITEYEQSLNDFNINSIKQKEQI 1007 Query: 821 DELVNRLAVLMDH-DRVVEKQLLEIEHENKELQKKNQIL--LEENQNLQISLSDMQ-QHY 876 L N++ L EK+ E E E+ K NQ L L+ + + D+Q +H+ Sbjct: 1008 KTLQNQIQSLNSEISNFNEKENEEKEKHKNEIDKLNQKLNDLQNQRKILHEQIDLQNEHH 1067 Query: 877 ----NALVEKANRTDLAESESTK-YQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIE 931 N + K N + + ++ + +Q ++++++ R ++ I K K+I+DLE E Sbjct: 1068 KKEMNDIQSKINELEKEKKKTIEDFQNKIKNIQEESDRKIKQNMDEIESKNKKIQDLEQE 1127 Query: 932 FNTQ---IESAIRD-----KKVLN----------EKYEKNIEYVTQLEAQLQEYKNNIEN 973 N Q IE +D ++V+N + +N + L + +E + IE Sbjct: 1128 RNNQQKMIEKLAKDNSDEYEEVVNLFNQQLDNLRQNNRQNENLIASLRSSNEEKQKEIEK 1187 Query: 974 LNMNVEELNKMNLEL---IDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQ 1030 L + EL K E+ D ++ +S + ++ ++I L + K +EI L + Sbjct: 1188 LVQEISELQKQISEIKNQNDFETERLLNESKEAKQKMASKIKDLESDKKFLQQEIEKLKR 1247 Query: 1031 KINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLL--DSKQHNEELQILVREQ 1088 +N MS D++ +L+Q + K++ + E + + KQ+ D Q N L L +++ Sbjct: 1248 INDNLNQQNMSQKRDFDEELSQKSNKIKELNERIIDLQKQINNDDLSQLNSRLHNLQKQK 1307 Query: 1089 D--DQIK-ELKETKLTFEMNIPK--TEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLK 1143 D DQ+ ELK K + I E + + ++D V +K Sbjct: 1308 DEVDQLNIELKNDKSNLQKQISSLAKEREDLKQQADSLNDYKKRVSDLEKEKENLVQNIK 1367 Query: 1144 VQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKL 1203 E + ++ Q ++ L T LQ+ QLE++ + + Q QL K Sbjct: 1368 -NMEIQISNQKDGNQPKNDALITALQK------QLESMKNRRENIEKDLKAQNQQLVDKN 1420 Query: 1204 EQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELR--VQL 1261 ++L + L+ + EL + Q+ +L K + KT+ EL ++ Sbjct: 1421 KELEEKVQELMHKITELNLELCKFKTQQRQLNRDLEKIQQENEKLKNAKTDSELNSSKRI 1480 Query: 1262 SAFESKYEQLLDSVQSSTQEETNKI-----VTMEQVTSLQNKLQDKEEHLRNLQ------ 1310 E++ E + ++ ++ E NKI + ++ LQ + Q+ E + NLQ Sbjct: 1481 EFLENQLENVNKQIEELSKAEANKIQNQLDMKNKENEQLQKEKQELAEKINNLQIILNEL 1540 Query: 1311 --------EKYADVINQIEIL-----RSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQ 1357 ++ +D+ QIE L SE +++++ + ++ Sbjct: 1541 QIKIEILEKEKSDLDKQIEKLNEDLNNSESKNKEIERQIFQLQNRKSDVNSQLNTLQVDK 1600 Query: 1358 SYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLE-LKD--S 1414 Y Q + N+E Q K ++N + +L+ +L+ LKD Sbjct: 1601 DYYQKIIDELHQKNDELVQRIKVLVDQLNELLKVKDQLNGSNEDLLKKITELQGLKDQLE 1660 Query: 1415 EIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYE 1474 E Y K + T+++ ++ ++V + L E +E + ES++ + ++ + + Sbjct: 1661 ENYLKLKDDNQTISEMKEQLDDVNELLKERISELEGIQESNESKIEEISNELDKYKSMTT 1720 Query: 1475 TMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIV 1534 + +EI+ + I+ +K + SLN+++ EL ++E +E+Q+ ++ Sbjct: 1721 DLNNLTEIDNIS-IDGSGIK-ERNDSLNEKIKELQDKIDELQRNYDELQSL----HTQVK 1774 Query: 1535 TLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLD 1582 N I + N + AS K+Q + + + LD +NK D Sbjct: 1775 DENSRIKDSYNELNASKEKLQINFDNLDQNNKKLESDLDK-LNKSFND 1821 Score = 155 bits (376), Expect = 1e-35 Identities = 236/1117 (21%), Positives = 484/1117 (43%), Gaps = 107/1117 (9%) Query: 149 NTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQI----IEAKNKATTXXXXXXXXXX 204 N+IK+K+ + LQ +++ + + I + EK NE+ + I+ N+ Sbjct: 999 NSIKQKEQ-IKTLQNQIQSLNSEISNFNEKENEEKEKHKNEIDKLNQKLNDLQNQRKILH 1057 Query: 205 XXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAAR 264 E K++M +Q +E E K++ ++D ++K I EE+++ ++ Sbjct: 1058 EQIDLQNEHHKKEMNDIQSKINELEKE----KKKTIEDFQNKIKNIQ--EESDRKIKQNM 1111 Query: 265 FEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTEL 324 EI ++ K+ Q+LEQ LAK + +E E+ + ++ N+ + Sbjct: 1112 DEIESKNKKI-QDLEQERNNQQKMIEK---LAKDN----SDEYEEVVNLFNQQLDNLRQN 1163 Query: 325 TKKIE-LLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMK 383 ++ E L+ L + KE+E + + K +S + R + +K K Sbjct: 1164 NRQNENLIASLRSSNEEKQKEIEKLVQEISELQKQISEIKNQNDFETERLLNESKEAKQK 1223 Query: 384 SPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNK-----------DLVDKEYVISEKD 432 ++S+ + ++DKK + EI KL+ + +LN+ +L K I E + Sbjct: 1224 -----MASKIKDLESDKKFLQQEIEKLKRINDNLNQQNMSQKRDFDEELSQKSNKIKELN 1278 Query: 433 TXXXXXXXXXXGKDTLIAQLQLEHQQHMEGP------SLIHVGTNTE-DVNEIAKVQEQL 485 D +L + Q + L + +N + ++ +AK +E L Sbjct: 1279 ERIIDLQKQINNDDLSQLNSRLHNLQKQKDEVDQLNIELKNDKSNLQKQISSLAKEREDL 1338 Query: 486 KQE---LNDEIKDVN-----VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKL 537 KQ+ LND K V+ ++L++ +K+ E QI+ D N +I + Sbjct: 1339 KQQADSLNDYKKRVSDLEKEKENLVQNIKNMEIQISNQKDGNQPKNDALITALQKQLESM 1398 Query: 538 KQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSG-RMIES 596 K ++ I+ K N+++V +EL +KV EL + L L L + + R + Sbjct: 1399 KNRRENIEKDLKAQ--NQQLVDKNKELE---EKVQELMHKITELNLELCKFKTQQRQLNR 1453 Query: 597 DVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVC 656 D+ K I+ EN K S L S K + L+ + + V ++ ++S+ +++++ Sbjct: 1454 DLEK--IQQENEKLKNAKTDSELNSSK-----RIEFLENQLENVNKQIEELSKAEANKIQ 1506 Query: 657 SEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQE 716 +++ + E + L K+ELA I NL++ +L I+ LE +K D+ +++ + E Sbjct: 1507 NQLDMKNKENE--QLQKEKQELAEKINNLQIILNELQIKIEILEKEKSDLDKQIEK-LNE 1563 Query: 717 NMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKS 776 +++ ++ K +I +L +S + +Q +Q Y + I EL + Sbjct: 1564 DLNNSESKNKEIERQIFQL-----QNRKSDVNSQLNT---LQVDKDYYQKIIDELHQKND 1615 Query: 777 RICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRV 836 L + I V+ D+ L + DQL ++ K +E +D+L L D ++ Sbjct: 1616 E---LVQRIKVLVDQLNELLKVKDQLNGSNEDLLKKITELQGLKDQLEENYLKLKDDNQT 1672 Query: 837 VEKQLLEIEHENKELQKKNQIL---LEENQNLQISLSDMQQHYNALVEKANRTDLAESES 893 + + +++ N+ L+++ L E N++ +S+ Y ++ N +L E ++ Sbjct: 1673 ISEMKEQLDDVNELLKERISELEGIQESNESKIEEISNELDKYKSMTTDLN--NLTEIDN 1730 Query: 894 TKYQ-TQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIE---SAIRDK-KVLNE 948 + +++ +L E Q I + ++ ++L+ +TQ++ S I+D LN Sbjct: 1731 ISIDGSGIKERNDSLNEKIKELQDKIDELQRNYDELQ-SLHTQVKDENSRIKDSYNELNA 1789 Query: 949 KYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQ----KQQTQSP-DY 1003 EK L+ ++ +++++ LN + +L + N +L D + Q K + QS D Sbjct: 1790 SKEKLQINFDNLDQNNKKLESDLDKLNKSFNDLLENNQQLQDNNNQLNEEKNKLQSDFDN 1849 Query: 1004 TEQYINEINKLNALLKQKDEEIIALNQKINNAQV-------SYMSMVSDYESKLAQFTTK 1056 ++ I + N+ L + + ++ N+ +N Q V + ++ + + Sbjct: 1850 SQNDIKKFNENINQLCESNNKLENANKDLNERQKILERDNNELKRQVENLMGEINKLNEE 1909 Query: 1057 LENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISS 1116 EN++ E + + +L+ Q+++E++ L +D+I+ L K E N+ E + S Sbjct: 1910 KENLDRERKSLEGELIKQNQNDDEIKRL----NDEIQSLNHHKKELEENLKLKENQL-SD 1964 Query: 1117 TIEPMSDDANNVDXXXXXXXXXXXXLKV-QEEEEFIQERSVLQEQSAKLNTELQECYTKI 1175 +S +N ++ LK Q E I++ + LQE+ KL ++ + Sbjct: 1965 LSNTLSTISNALNSQISGLKEQIEELKQKQNPNELIEKLNELQEEKKKLEQDITDKDKLN 2024 Query: 1176 IQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDN 1212 +L+ EL + E+I QL K L ND+ Sbjct: 2025 EELQKRVDELEKEKQNHYEEIQQLNLKTRDLELNNDD 2061 Score = 154 bits (373), Expect = 2e-35 Identities = 285/1391 (20%), Positives = 579/1391 (41%), Gaps = 103/1391 (7%) Query: 234 DEKQRLLKDIESKDVRISSL-EEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXX 292 D+ +L D +S + SL +E + +E AR E E +K + L Sbjct: 644 DKISKLESDKKSYQDKYESLSKELDYNIENARKEYE-EKTKDLRRLYDKNIQDLSDLQKG 702 Query: 293 XXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQT---NKELENKL 349 + ++ +E EEK EE+ + E+ + + + L Q ++ N EL+ +L Sbjct: 703 KQILERKLEE--EEKKHEEEREWERNKSQEEIKRGLNRIIELESQQKRIYIENDELKERL 760 Query: 350 ATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKIN--KNEI 407 T+ + VS K I ++ N K+ + Q + LN +N KNE Sbjct: 761 QTVYID---VSEKFKNEFEFIKKQYEDNI--KVLNDRQQEEIDQLNLQNKNMLNVLKNEK 815 Query: 408 AKLEMVIQSLN---KDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPS 464 ++ + KDL DK ++ ++ K +Q+ + + Sbjct: 816 IIVQNQLNEARQRVKDLEDKNQILLDQKQTREDGIDRIEEKQREYEDKISSLEQNFDHLN 875 Query: 465 LIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANK 524 L H + EI K++ + +Q +N + D N +K+ + + N EI+ N+ Sbjct: 876 LEHQKDMEKLQAEIKKLESEKQQLINKMMNDHNSNKDQKKMNEIISDLQKRNSEIEQKNQ 935 Query: 525 NMIKVKSNHKLKLKQMQKTIDNFS-KVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQL 583 ++ Q+++ ID KV++ + E ++ +E ++ Q +++ E+EK LQ Sbjct: 936 -----------EINQLKQEIDQEKEKVTNLDTEKSKMQKEKINMEQIISQNEQEKKELQQ 984 Query: 584 HLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDK 643 + +Y+ +D I+ + +T I L S+ + ++ + ++K+ DK Sbjct: 985 VITEYEQSL---NDFNINSIKQKEQIKTLQNQIQSLNSEISNFNEKENEEKEKHKNEIDK 1041 Query: 644 LAD-ISQLQSDQVCSEIKSVHLEEQIDALSAS-KKELALVIENL-KLDKEQLYGTIKDLE 700 L ++ LQ+ + K +H EQID + KKE+ + + +L+KE+ TI+D + Sbjct: 1042 LNQKLNDLQNQR-----KILH--EQIDLQNEHHKKEMNDIQSKINELEKEKKK-TIEDFQ 1093 Query: 701 NDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQER 760 N ++I + I++NMD + K KI +L + N+ Q K+ + D E Sbjct: 1094 NKIKNIQEESDRKIKQNMDEIESKNK----KIQDLEQERNN--QQKMIEKLAKDNS-DEY 1146 Query: 761 DLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQE 820 + + +L + + E IA + +++ ++L + E QK SE Q Sbjct: 1147 EEVVNLFNQQLDNLRQNNRQNENLIASLRSSNEEKQKEIEKLVQEISELQKQISEIKNQN 1206 Query: 821 DELVNRLA-VLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNL-QISLSDMQQHYNA 878 D RL + + + ++ ++E + K LQ++ + L N NL Q ++S + Sbjct: 1207 DFETERLLNESKEAKQKMASKIKDLESDKKFLQQEIEKLKRINDNLNQQNMSQKRDFDEE 1266 Query: 879 LVEKANRTDLAESESTKYQTQLRDLE-SNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIE 937 L +K+N+ Q Q+ + + S L H Q ++K E++ L IE + Sbjct: 1267 LSQKSNKIKELNERIIDLQKQINNDDLSQLNSRLHNLQ----KQKDEVDQLNIELKN--D 1320 Query: 938 SAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQ 997 + K++ + E+ E + Q L +YK + +L E L + N++ ++ + Q+ Sbjct: 1321 KSNLQKQISSLAKER--EDLKQQADSLNDYKKRVSDLEKEKENLVQ-NIKNMEIQISNQK 1377 Query: 998 TQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKL 1057 + + I + K +K + E I + K N Q+ + + E K+ + K+ Sbjct: 1378 DGNQPKNDALITALQKQLESMKNRRENI-EKDLKAQNQQL--VDKNKELEEKVQELMHKI 1434 Query: 1058 ENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISST 1117 + E+ + Q +Q N +L+ + +E + +LK K E+N K + + Sbjct: 1435 TELNLELCKFKTQ---QRQLNRDLEKIQQENE----KLKNAKTDSELNSSKRIEFL-ENQ 1486 Query: 1118 IEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQ 1177 +E ++ + +K +E E+ +E+ L E+ L L E KI Sbjct: 1487 LENVNKQIEELSKAEANKIQNQLDMKNKENEQLQKEKQELAEKINNLQIILNELQIKIEI 1546 Query: 1178 LETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAE 1237 LE ++L E +N +SK +++ + L + +++ S +++ + + Sbjct: 1547 LEKEKSDLDKQIEKLNEDLNNSESKNKEIERQIFQLQNRKSDVNSQLNTLQVDKDYYQKI 1606 Query: 1238 LWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQN 1297 + + H Q+ + + L QL+ +QL S + ++ T +Q+ Sbjct: 1607 IDELH--QKNDELVQRIKVLVDQLNELLKVKDQLNGSNEDLLKKITELQGLKDQLEENYL 1664 Query: 1298 KLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQ 1357 KL+D + + ++E+ DV ++ SE+E + + ++ E Sbjct: 1665 KLKDDNQTISEMKEQLDDVNELLKERISELEGIQES-----------NESKIEEISNELD 1713 Query: 1358 SYKQMQEQ-----SILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTH---QL 1409 YK M I NI+ + + +K+ + ++++ + EL Q+ Sbjct: 1714 KYKSMTTDLNNLTEIDNISIDGSGIKERNDSLNEKIKELQDKIDELQRNYDELQSLHTQV 1773 Query: 1410 ELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHEN 1469 + ++S I +E + + F+N+ Q + E ++ L + ++L ++ +N Sbjct: 1774 KDENSRIKDSYNELNASKEKLQINFDNLDQNNKKLESDLDKLN-KSFNDLLENNQQLQDN 1832 Query: 1470 ANHY--ETMQKESEIERVKL-IEELNVKITESVSLNKQVAELNKALEEEVA----KTNEM 1522 N E + +S+ + + I++ N I + N ++ NK L E NE+ Sbjct: 1833 NNQLNEEKNKLQSDFDNSQNDIKKFNENINQLCESNNKLENANKDLNERQKILERDNNEL 1892 Query: 1523 QTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDE-QLDNTMNKELL 1581 + +EN EI LN+E NL ++ ++ K + K+ DE Q N KEL Sbjct: 1893 KRQVENLMGEINKLNEEKENLDRERKSLEGELIKQNQNDDEIKRLNDEIQSLNHHKKELE 1952 Query: 1582 DAVPRAELDLA 1592 + + E L+ Sbjct: 1953 ENLKLKENQLS 1963 Score = 131 bits (316), Expect = 2e-28 Identities = 193/882 (21%), Positives = 393/882 (44%), Gaps = 83/882 (9%) Query: 143 DVTHLSNTIKEKDNALSVLQVK-----MKIMETTILDLQEKINEKDQI-IEAKNKATTXX 196 +++ SN IKE + + LQ + + + + + +LQ++ +E DQ+ IE KN + Sbjct: 1266 ELSQKSNKIKELNERIIDLQKQINNDDLSQLNSRLHNLQKQKDEVDQLNIELKNDKSNLQ 1325 Query: 197 XXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEA 256 ED KQQ + + + ++ + EK+ L+++I++ +++IS+ ++ Sbjct: 1326 KQISSLAKER-----EDLKQQADSLND-YKKRVSDLEKEKENLVQNIKNMEIQISNQKDG 1379 Query: 257 NKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSL 316 N+ A + L ++LE +Q ++ + E+EEK Sbjct: 1380 NQPKNDALI------TALQKQLESMKNRRENIEKDLKAQNQQLVD----KNKELEEKVQE 1429 Query: 317 EIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSP--LISRKS 374 + +TEL +EL + Q RQ N++LE K+ + K + S+ S + ++ Sbjct: 1430 LMHKITELN--LELCK-FKTQQRQLNRDLE-KIQQENEKLKNAKTDSELNSSKRIEFLEN 1485 Query: 375 GRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTX 434 +K S+ + + D K +NE +L+ Q L + + + + +++E Sbjct: 1486 QLENVNKQIEELSKAEANKIQNQLDMKNKENE--QLQKEKQELAEKINNLQIILNELQIK 1543 Query: 435 XXXXXXXXXGKDTLIAQLQLEHQQHMEGPS------LIHVGTNTEDVNE---IAKVQEQL 485 D I +L E + E + + + DVN +V + Sbjct: 1544 IEILEKEKSDLDKQIEKLN-EDLNNSESKNKEIERQIFQLQNRKSDVNSQLNTLQVDKDY 1602 Query: 486 KQELNDEIKDVNVKDLIEKLKSAEEQITQL---NDEIDAANKNMIKVKSNHKLKLKQMQK 542 Q++ DE+ N +L++++K +Q+ +L D+++ +N++++K K LK + Sbjct: 1603 YQKIIDELHQKN-DELVQRIKVLVDQLNELLKVKDQLNGSNEDLLK-KITELQGLKDQLE 1660 Query: 543 TIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKM 602 +N+ K+ D N+ I + E+L +++ + E E +Q E D YK M Sbjct: 1661 --ENYLKLKDDNQTISEMKEQLDDVNELLKERISELEGIQESNESKIEEISNELDKYKSM 1718 Query: 603 I-EMENLAETRLKAI--SLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEI 659 ++ NL E +I S ++ + L +++ LQ K DE++ ++ L + QV E Sbjct: 1719 TTDLNNLTEIDNISIDGSGIKERNDSLNEKIKELQDKIDELQRNYDELQSLHT-QVKDE- 1776 Query: 660 KSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMD 719 + +++ + L+ASK++L + +NL + ++L + L D++ Q N Sbjct: 1777 -NSRIKDSYNELNASKEKLQINFDNLDQNNKKLESDLDKLNKSFNDLLENNQQLQDNNNQ 1835 Query: 720 LTDKLEKM------SAEKISELLAKINH--EEQSKIQTQFGIDAKIQERDLYIENIESEL 771 L ++ K+ S I + IN E +K++ + + ER +E +EL Sbjct: 1836 LNEEKNKLQSDFDNSQNDIKKFNENINQLCESNNKLE---NANKDLNERQKILERDNNEL 1892 Query: 772 SKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLM 831 K ++ L I + + + +L+R+ L L ++ + E DE+ + L Sbjct: 1893 ---KRQVENLMGEINKLNEEKENLDRERKSLEGELIKQNQNDDEIKRLNDEIQS----LN 1945 Query: 832 DHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAES 891 H + +E+ L E++ +L + L + L +S +++ L +K N +L E Sbjct: 1946 HHKKELEENLKLKENQLSDL---SNTLSTISNALNSQISGLKEQIEELKQKQNPNELIE- 2001 Query: 892 ESTKYQTQLRDLESNL---KRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNE 948 + + Q + + LE ++ ++ E Q + + +KE ++ E Q+ RD + LN Sbjct: 2002 KLNELQEEKKKLEQDITDKDKLNEELQKRVDELEKEKQN-HYEEIQQLNLKTRDLE-LNN 2059 Query: 949 KYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNK--MNLEL 988 E IE V Q++ ++ ++KN IENLN ++ L NL+L Sbjct: 2060 DDEDQIE-VVQIKQKIDDHKNEIENLNKLIDSLRNDISNLKL 2100 Score = 122 bits (295), Expect = 6e-26 Identities = 224/1190 (18%), Positives = 521/1190 (43%), Gaps = 120/1190 (10%) Query: 477 EIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQI-----TQLNDEIDAANKNMIKVKS 531 E+ Q+ + Q + + IK VN ++ ++ E + ++L D+ ++ ++ Sbjct: 330 EVIDEQKNILQSVINSIKQVNEQEFNKQKSQNHENVDNEAKSKLFDQKQQFVSSISQIME 389 Query: 532 NHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHL---VDY 588 ++ K+ K N + + SN+EI R+ + L++K+++LE++ L+ ++Y Sbjct: 390 ELQVLYKEQHK---NNNMIRISNQEIERINLKEFDLNEKLSKLEQDLEMLREQRKIEIEY 446 Query: 589 DSGRM--IESD---VYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDK 643 ++ + IES+ + + E + L S E K ++ + + L+ D+ Sbjct: 447 NNRAVEAIESEKASLRTRRNEFQKLLNDPATNDSDKELYKGEIEKLILQLKNLDDDKNAF 506 Query: 644 LADISQLQSDQ------VCSEIKSVHLE----EQIDA--LSASKKELALVIENLKLDKEQ 691 +A+ L+ + + +I++ E E IDA + + ++ L++EN +Q Sbjct: 507 IAENDDLKKEDGLEAKVIIQQIQTAQNEKNSFEAIDANNVEFHQNKIKLLVENQNKISDQ 566 Query: 692 LYGTIKDLENDKEDIMNKLQN----YIQENMDLTDKLEKMSAEKISELLAKINHEEQSKI 747 + K LE K + L+ + EN L DK+ +M E ++ L+ I+ + Q+ Sbjct: 567 ICLLRKQLEEQKYSYNSLLEEENKLFDLENAPL-DKIYEMEVEMLNNQLSMIDKQRQNLQ 625 Query: 748 QTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQ 807 ++ K E + + S+L K ES++ ++ Y++E + + Sbjct: 626 SELDSVNHKHYETTNMLNDKISKLESDKKSYQDKYESLS--KELDYNIENARKEYEEKTK 683 Query: 808 EKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQI 867 + ++ Y + +L +L +R +E++ + E E + + K+Q ++ N I Sbjct: 684 DLRRLYDKNIQDLSDLQKGKQIL---ERKLEEEEKKHEEEREWERNKSQEEIKRGLNRII 740 Query: 868 SLSDMQQHY----NALVEKANRT--DLAESESTKYQTQLRDLESNLK----RITHEHQTL 917 L Q+ + L E+ D++E +++ + E N+K R E L Sbjct: 741 ELESQQKRIYIENDELKERLQTVYIDVSEKFKNEFEFIKKQYEDNIKVLNDRQQEEIDQL 800 Query: 918 IVQKKKEIEDLEIE---FNTQIESA------IRDK-KVLNEKYEKNIEYVTQLEAQLQEY 967 +Q K + L+ E Q+ A + DK ++L ++ + + + ++E + +EY Sbjct: 801 NLQNKNMLNVLKNEKIIVQNQLNEARQRVKDLEDKNQILLDQKQTREDGIDRIEEKQREY 860 Query: 968 KNNIENLNMNVEELN---KMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEE 1024 ++ I +L N + LN + ++E + ++K +++ + +N+ N ++K E Sbjct: 861 EDKISSLEQNFDHLNLEHQKDMEKLQAEIKKLESEKQQLINKMMNDHNSNKD--QKKMNE 918 Query: 1025 IIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQIL 1084 II+ QK N+ ++ + ++ Q K+ N++ E ++ K+ ++ +Q + + Sbjct: 919 IISDLQKRNSEIEQKNQEINQLKQEIDQEKEKVTNLDTEKSKMQKEKINMEQIISQNEQE 978 Query: 1085 VREQDDQIKELKETKLTFEMNIPKTEGMI--ISSTIEPMSDDANNVDXXXXXXXXXXXXL 1142 +E I E +++ F +N K + I + + I+ ++ + +N + Sbjct: 979 KKELQQVITEYEQSLNDFNINSIKQKEQIKTLQNQIQSLNSEISNFNE------------ 1026 Query: 1143 KVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSK 1202 +E EE + ++ + + + KLN +LQ Q + L+ ++ + +++++N ++SK Sbjct: 1027 --KENEEKEKHKNEIDKLNQKLN-DLQN------QRKILHEQIDLQNEHHKKEMNDIQSK 1077 Query: 1203 LEQLNTEN----DNLLSTVAELRSSISSAVDQRGFEIAELWK--QHLAQREADFQKTEHE 1256 + +L E ++ + + ++ + Q EI K Q L Q + QK + Sbjct: 1078 INELEKEKKKTIEDFQNKIKNIQEESDRKIKQNMDEIESKNKKIQDLEQERNNQQKMIEK 1137 Query: 1257 LRVQLS-AFE---SKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEK 1312 L S +E + + Q LD+++ + ++ N I SL++ ++K++ + L ++ Sbjct: 1138 LAKDNSDEYEEVVNLFNQQLDNLRQNNRQNENLI------ASLRSSNEEKQKEIEKLVQE 1191 Query: 1313 YADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINE 1372 +++ QI ++++ + E DL ++ + + Q + + + IN+ Sbjct: 1192 ISELQKQISEIKNQNDFETERLLNESKEAKQKMASKIKDLESD-KKFLQQEIEKLKRIND 1250 Query: 1373 E-NAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKD-SEIYQKTH---EYTITL 1427 N Q ++ + ++++L Q+ D S++ + H + + Sbjct: 1251 NLNQQNMSQKRDFDEELSQKSNKIKELNERIIDLQKQINNDDLSQLNSRLHNLQKQKDEV 1310 Query: 1428 TQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKL 1487 Q N E +N + L +K+I L E+E +L +++ ++KE E V+ Sbjct: 1311 DQLNIELKNDKSNL---QKQISSLAKERE-DLKQQADSLNDYKKRVSDLEKEKE-NLVQN 1365 Query: 1488 IEELNVKITESVSLNKQ-----VAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEI-T 1541 I+ + ++I+ N+ + L K LE + ++ L+ Q ++V N E+ Sbjct: 1366 IKNMEIQISNQKDGNQPKNDALITALQKQLESMKNRRENIEKDLKAQNQQLVDKNKELEE 1425 Query: 1542 NLQNMVRASSSKIQKHVSFASDTKQ-GRDEQLDNTMNKELLDAVPRAELD 1590 +Q ++ + + F + +Q RD + N++L +A +EL+ Sbjct: 1426 KVQELMHKITELNLELCKFKTQQRQLNRDLEKIQQENEKLKNAKTDSELN 1475 Score = 117 bits (281), Expect = 3e-24 Identities = 218/1184 (18%), Positives = 512/1184 (43%), Gaps = 125/1184 (10%) Query: 483 EQLKQELNDEIKDVNVKDLIEKLKSAEE------QITQLNDEIDAANKNMIKVKSNHKL- 535 E +K+E +++K++ +E K AEE +I DE++ ++ M ++ S + Sbjct: 184 ETIKKEHEEKLKEIESDTKLEADKIAEERKAKQKEIDLKTDELERVDRTMREIDSKRRRS 243 Query: 536 -KLKQMQKT-IDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRM 593 L ++ K+ + S DS K+ E ++ K LE++K N++ + Sbjct: 244 ESLARLYKSKVSLLSDELDSQKKCFNEVEGRNNTIMKEI-LEQKKENIR---QSEKLQQK 299 Query: 594 IESDV--YKKMIEMENLAETR-----LKAISLLESQKFDLVQELHILQQKYDEVEDKLAD 646 +D+ ++K+++ E L A+ +++ QK L ++ ++Q ++ +K Sbjct: 300 FNNDLFNFQKILDNERLQHNNDINSLNNALEVIDEQKNILQSVINSIKQVNEQEFNKQKS 359 Query: 647 ISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLE--NDKE 704 + D ++ + ++S +EL ++ + + + + +++E N KE Sbjct: 360 QNHENVDNEAKSKLFDQKQQFVSSISQIMEELQVLYKEQHKNNNMIRISNQEIERINLKE 419 Query: 705 DIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYI 764 +N+ + +++++++ + K+ E + + I E+ S ++T+ K+ D Sbjct: 420 FDLNEKLSKLEQDLEMLREQRKIEIEYNNRAVEAIESEKAS-LRTRRNEFQKLL-NDPAT 477 Query: 765 ENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELV 824 + + EL YK I +L +++ L+ D +++ E E ++ ++ Sbjct: 478 NDSDKEL--YKGEIEKL-----ILQ-----LKNLDDDKNAFIAENDDLKKEDGLEAKVII 525 Query: 825 NRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQN--------LQISLSDMQQHY 876 ++ + E I+ N E + LL ENQN L+ L + + Y Sbjct: 526 QQIQTAQNEKNSFE----AIDANNVEFHQNKIKLLVENQNKISDQICLLRKQLEEQKYSY 581 Query: 877 NALVEKANRT-DLAESESTK-YQTQLRDLESNLKRITHEHQTLIVQ----KKKEIEDLEI 930 N+L+E+ N+ DL + K Y+ ++ L + L I + Q L + K E + Sbjct: 582 NSLLEEENKLFDLENAPLDKIYEMEVEMLNNQLSMIDKQRQNLQSELDSVNHKHYETTNM 641 Query: 931 EFNTQIESAIRDKKVLNEKYE---KNIEYVTQLEAQLQEYKNNIENL----NMNVEELNK 983 N +I DKK +KYE K ++Y +E +EY+ ++L + N+++L+ Sbjct: 642 -LNDKISKLESDKKSYQDKYESLSKELDY--NIENARKEYEEKTKDLRRLYDKNIQDLSD 698 Query: 984 M--NLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMS 1041 + +++++ +++++ + + E E NK +K+ II L + + Sbjct: 699 LQKGKQILERKLEEEEKKHEEEREW---ERNKSQEEIKRGLNRIIELESQQKRIYIENDE 755 Query: 1042 MVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLT 1101 + ++ + K +N E ++ KQ+ + +++L Q ++I +L Sbjct: 756 LKERLQTVYIDVSEKFKNEFEFIK---------KQYEDNIKVLNDRQQEEIDQLNLQNKN 806 Query: 1102 FEMNIPKTEGMIISSTIEPMS------DDANNVDXXXXXXXXXXXXLKVQEEEEFIQERS 1155 +N+ K E +I+ + + +D N + +++ E+ + S Sbjct: 807 M-LNVLKNEKIIVQNQLNEARQRVKDLEDKNQILLDQKQTREDGIDRIEEKQREYEDKIS 865 Query: 1156 VLQEQSAKLNTE----LQECYTKIIQLET-----LNTELTGHDV-VNQEQINQLKSKLEQ 1205 L++ LN E +++ +I +LE+ +N + H+ +Q+++N++ S L++ Sbjct: 866 SLEQNFDHLNLEHQKDMEKLQAEIKKLESEKQQLINKMMNDHNSNKDQKKMNEIISDLQK 925 Query: 1206 LNTENDNLLSTVAELRSSI---SSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLS 1262 N+E + + +L+ I V E +++ K+ + E + E E + +L Sbjct: 926 RNSEIEQKNQEINQLKQEIDQEKEKVTNLDTEKSKMQKEKI-NMEQIISQNEQE-KKELQ 983 Query: 1263 AFESKYEQLLDSVQSSTQEETNKIVTME-QVTSLQNKLQDKEEHLRNLQEKYADVINQIE 1321 ++YEQ L+ ++ ++ +I T++ Q+ SL +++ + E +EK+ + I+++ Sbjct: 984 QVITEYEQSLNDFNINSIKQKEQIKTLQNQIQSLNSEISNFNEKENEEKEKHKNEIDKLN 1043 Query: 1322 ILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTE-NQSYKQMQ------EQSILNINEEN 1374 +++++++ D++++ N+ K+ + + I NI EE+ Sbjct: 1044 QKLNDLQNQRKILHEQIDLQNEHHKKEMNDIQSKINELEKEKKKTIEDFQNKIKNIQEES 1103 Query: 1375 AQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEF 1434 + K + ++ D E E +Q ++ + + EY + N + Sbjct: 1104 DRKIKQN---MDEIESKNKKIQDLEQ---ERNNQQKMIEKLAKDNSDEYEEVVNLFNQQL 1157 Query: 1435 ENVRQQLVEYEKRIEDL---TYEKESELAILRLKMHENANHYETMQKESEIERVKLIEEL 1491 +N+RQ + E I L EK+ E+ L ++ E ++ +++ E +L+ E Sbjct: 1158 DNLRQNNRQNENLIASLRSSNEEKQKEIEKLVQEISELQKQISEIKNQNDFETERLLNES 1217 Query: 1492 NVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEI-EIVTLNDEITNLQNMVRAS 1550 + S K + K L++E+ K + L Q + + ++E++ N ++ Sbjct: 1218 KEAKQKMASKIKDLESDKKFLQQEIEKLKRINDNLNQQNMSQKRDFDEELSQKSNKIKEL 1277 Query: 1551 SSKI---QKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDL 1591 + +I QK ++ +D + +L N ++ D V + ++L Sbjct: 1278 NERIIDLQKQIN--NDDLSQLNSRLHNLQKQK--DEVDQLNIEL 1317 Score = 39.1 bits (87), Expect = 0.99 Identities = 61/327 (18%), Positives = 125/327 (38%), Gaps = 20/327 (6%) Query: 220 KMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELE 279 K+Q NF ++ ++L D++ + + L E N+ L+ +++ E +KL + + Sbjct: 1793 KLQINFDNLD----QNNKKLESDLDKLNKSFNDLLENNQQLQDNNNQLNEEKNKLQSDFD 1848 Query: 280 QXXXXXXXXXXXXXXLAK-----QSIEPSCEEKTEIEEKGSLEIANMTE-LTKKIELLEH 333 L + ++ E+ +I E+ + E+ E L +I L Sbjct: 1849 NSQNDIKKFNENINQLCESNNKLENANKDLNERQKILERDNNELKRQVENLMGEINKLNE 1908 Query: 334 LNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSET 393 + + K LE +L + + + L K K+K +QLS + Sbjct: 1909 EKENLDRERKSLEGELIKQNQNDDEIKRLNDEIQSLNHHKKELEENLKLKE--NQLSDLS 1966 Query: 394 LNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYV--ISEKDTXXXXXXXXXXGKDTLIAQ 451 T ++I+ L+ I+ L + E + ++E KD L + Sbjct: 1967 NTLSTISNALNSQISGLKEQIEELKQKQNPNELIEKLNELQEEKKKLEQDITDKDKLNEE 2026 Query: 452 LQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQ 511 LQ + +E H E++ ++ L+ ND+ + V + +K+ + + Sbjct: 2027 LQ-KRVDELEKEKQNHY----EEIQQLNLKTRDLELN-NDDEDQIEVVQIKQKIDDHKNE 2080 Query: 512 ITQLNDEIDAANKNMIKVKSNHKLKLK 538 I LN ID+ ++ +K + K K Sbjct: 2081 IENLNKLIDSLRNDISNLKLENSRKAK 2107 >UniRef50_UPI00006CF26E Cluster: Viral A-type inclusion protein repeat containing protein; n=1; Tetrahymena thermophila SB210|Rep: Viral A-type inclusion protein repeat containing protein - Tetrahymena thermophila SB210 Length = 2519 Score = 172 bits (419), Expect = 6e-41 Identities = 294/1457 (20%), Positives = 638/1457 (43%), Gaps = 125/1457 (8%) Query: 140 QLGDVTHLSNTIKEKDNALSVLQVKMKIM--------ETTILDLQEKINEKDQIIEAKNK 191 +L D + + I E++ LS +MK+M E T+ L++ I EK + + N+ Sbjct: 666 KLNDQERMIDQIVEENQMLSKELEQMKLMQEFKQAQHEETVHQLKKLIAEKSNVTDEMNQ 725 Query: 192 ATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRIS 251 ++ + ++ M E K ++ LK +E + + Sbjct: 726 ELRLRNIDLVEQIKQLQQQNLLLNERSKESEKQRQDMAEEKKQAHEKYLKYLEKYNEETT 785 Query: 252 SLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIE 311 L+ + + L + E E+ ++ E+ Q AKQ ++ S +++ E + Sbjct: 786 HLQASIQELTSNFNEKEFENLRIKDEVIQGNERIRELESNISQ-AKQ-VQDSLQQEIE-Q 842 Query: 312 EKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLIS 371 +K +E +L +++ LE + Q + +E+E T+ + K+ + L++ Sbjct: 843 KKNQIE-----QLEEQLIELEEADNQRKDLQEEIETLNETLNFRENELEEMKKQKTQLLN 897 Query: 372 RKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEK 431 + A Q + ++ + + N+ LE ++ + K ++ E V+ E+ Sbjct: 898 QIQELQAAKVQIEELVQTLKMRI-EELESQNNEQNNKLLEEKVEEVKK--LEDEKVVIEQ 954 Query: 432 DTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELND 491 + D ++ Q +LE + +E + + +NEI+ +E++ Q L Sbjct: 955 ELNEIRKTKEA---DNIVIQNKLEQIKSLEQEKVFV----QQKINEISDEKERITQVLEG 1007 Query: 492 EIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQ----KTIDNF 547 EIK + K L+E ++ +E I Q EI+ + ++KS+ + +++ K +NF Sbjct: 1008 EIKILKEKLLLEDDQN-QEVINQKQTEIEQLRSQVQQLKSSIQKEIESFNNEKTKLEENF 1066 Query: 548 SKVSDSNKEIVR--LTEELHHLSQKVA-ELEE--EKGNLQLHLVDYDSGRMIESDVYKKM 602 K + L E+ L Q + ELE+ E ++ ++ + ++I+ + Sbjct: 1067 KKEKQETLLQCKRDLQEQCEQLQQNFSIELEKQIEIREKKIAKLEEEKSKVIQQSQEETQ 1126 Query: 603 IEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSD-QVCSEIKS 661 E+E L E + + L+ QK +Q+ I+++ +E++ L + QL Q+ + Sbjct: 1127 QELETLKEDLERQVVLITEQKDQEIQQ--IIEKNSEELQGLLNEKQQLLKQIQLNKDEIQ 1184 Query: 662 VHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLT 721 +H + I A +EL E+ ++KE LY + N ++ +KL++ E+ L Sbjct: 1185 MH-QNSIQAYEQQIQEL----ESSLIEKEGLY---IEKNNAFKEQQSKLRHLESESSQLK 1236 Query: 722 DKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYI-ENIESELSKYKSRICR 780 ++ +++ +K S+L + + Q+ + + ++ K+Q LY E I + + K R Sbjct: 1237 EEAQELK-DKASQLAESLEGQTQAYSKAKAEVE-KLQNEILYQQEKILQQENTIKILKER 1294 Query: 781 LEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELV----NRLAVL-MDHDR 835 +E + E Y LE K QL K ++ + DE + N +A L ++ + Sbjct: 1295 QQEESSQSEKYVYELEDKVRQLEQEKASMVKLNNQLQQESDEKLLDKENEIAHLNLEKKQ 1354 Query: 836 VVEKQLLEIEHENKELQKKNQILLEENQ---NLQIS-LSDMQQHYNALVEKANRTDLAES 891 +++ +L EIE K Q+ I L++ + N +I L ++ Q A+ EK E Sbjct: 1355 ILDSKLQEIEEIVKLQQQDKDISLQKQELIFNERIKELEELVQQ--AISEKEIIITQYED 1412 Query: 892 ESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYE 951 ++ + + ++ DL LK+I + Q I + +EI+ L + + + +K E YE Sbjct: 1413 KNNEKENKISDL---LKQIEEQSQN-IQNQNEEIDSLNQQVILLRQKISQKEKEKQENYE 1468 Query: 952 KNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEI 1011 + + L +++Y +NL +++E + + +++ ++ Q Q + E + ++I Sbjct: 1469 RESKEKQDL---IEKYAEEKQNLQISLENRFSVKQKQMEEQIKSYQEQLSNEQEAHQSQI 1525 Query: 1012 NKLNALLKQKDEEIIALNQKINNAQVSYMSMVSD----YESKLAQ---FTTKLENMEEEM 1064 + ++++ I L +I + +S+ YE++ + ++EN+++E+ Sbjct: 1526 EQKEMIIEEHQNIIDELKTEIEGLKTQRYEKLSEQEQLYENQQQENRLLVKQIENLKKEI 1585 Query: 1065 QRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDD 1124 S+QL+ ++ +E Q ++ D QIK+++E K + E+N + E T E + Sbjct: 1586 VNKSEQLIAEREEQQETQ---QQFDMQIKQIEE-KSSQEINKIQQESQEAIETAEKQILE 1641 Query: 1125 ANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTE 1184 + Q+EEE Q ++++ +L LQE + + L + Sbjct: 1642 LKR----------QLEKIIKQKEEELQQANKLVEQVKEQL---LQEKNQSVKENNNLIQK 1688 Query: 1185 LTGHDVVNQEQINQLKSKLEQL--NTENDNLL--STVAELRSSISSAVDQRGFEIAELWK 1240 + + ++N+LK + +Q+ EN+ L+ T A L+ I+ Q +L + Sbjct: 1689 IEQQQQLQLRELNELKEQNKQILAEAENNQLVFNQTEANLQEQIAYLKQQLDISNNKLEE 1748 Query: 1241 QH--LAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNK 1298 +H Q+ + QK E E Q + E L D + +E+ M ++ +N+ Sbjct: 1749 EHNKFLQKFTNLQK-EAEQNTQKQVLLN--EALRDEKWKAEKEQILHSHKMT-ISQKENE 1804 Query: 1299 LQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQS 1358 L +K + L ++++ + + ++++++ + + + TE S Sbjct: 1805 LFEKNQELLQMKQQLEEFKSLSHTYQTKLKEIQESNEKQSVINTQIFTKQLDQVNTEKNS 1864 Query: 1359 YKQMQEQSILNINEENAQLKKS--SXXXXXXXXXXXXRVN-DAEAKVLELTHQLELKDSE 1415 KQ E + E+ + +K ++N + E K+++L+ ++ +D+ Sbjct: 1865 LKQNLENLNAKLQEKAEETQKLIVQNGEYLTKAHQLEQLNQEKETKIIQLSKNIQQQDTY 1924 Query: 1416 IYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYET 1475 I QKT + + Q+ D + + + EY K I+ + + +++ + ++ + + Sbjct: 1925 I-QKTAQ---EIQQKKDIIQTLNE---EYSKVIQQ-NEQLKHQISETQTQLEKQS----I 1972 Query: 1476 MQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEE--VAKTNEMQTALENQEIEI 1533 + K+ E+ER++L+ + ++ E NK ELNK EE + + E Q ++ EIE Sbjct: 1973 IHKQKEVERLELVHKSKLEELE----NKHNEELNKIFEERRIMLEQLEEQKQQKDSEIEE 2028 Query: 1534 VTLN--DEITNLQNMVR 1548 + L +EI N + + + Sbjct: 2029 LCLKYAEEIDNFKKLTK 2045 Score = 165 bits (402), Expect = 7e-39 Identities = 268/1411 (18%), Positives = 609/1411 (43%), Gaps = 120/1411 (8%) Query: 144 VTHLSNTIKEKDNALSVLQVK-MKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXX 202 + L + E++N L +V+ +K +E + +++++NE + EA N Sbjct: 920 IEELESQNNEQNNKLLEEKVEEVKKLEDEKVVIEQELNEIRKTKEADNIVIQNKLEQIKS 979 Query: 203 XXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLL-KDIESKDV---RISSLEEANK 258 + + + + +E E K K++LL +D ++++V + + +E+ Sbjct: 980 LEQEKVFVQQKINEISDEKERITQVLEGEIKILKEKLLLEDDQNQEVINQKQTEIEQLRS 1039 Query: 259 LLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEI 318 ++ + I E E + K+ ++ CE+ +++ S+E+ Sbjct: 1040 QVQQLKSSIQKEIESFNNEKTKLEENFKKEKQETLLQCKRDLQEQCEQ---LQQNFSIEL 1096 Query: 319 ANMTELT-KKIELLEHLNCQ-IRQTNKELENKLATM--GTESKAVSSPSKKGSPL--ISR 372 E+ KKI LE + I+Q+ +E + +L T+ E + V +K + I Sbjct: 1097 EKQIEIREKKIAKLEEEKSKVIQQSQEETQQELETLKEDLERQVVLITEQKDQEIQQIIE 1156 Query: 373 KSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKD 432 K+ + L LN+D + ++++N I E IQ L L++KE + EK+ Sbjct: 1157 KNSEELQGLLNEKQQLLKQIQLNKD-EIQMHQNSIQAYEQQIQELESSLIEKEGLYIEKN 1215 Query: 433 TXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLI--HVGTNTEDVNEIAKVQEQLKQE-L 489 ++ +QL+ E Q+ + S + + T+ ++ E+L+ E L Sbjct: 1216 NAFKEQQSKLRHLESESSQLKEEAQELKDKASQLAESLEGQTQAYSKAKAEVEKLQNEIL 1275 Query: 490 NDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFS- 548 + K + ++ I+ LK +++ + +++ ++ ++ K + ++ + S Sbjct: 1276 YQQEKILQQENTIKILKERQQEESSQSEKYVYELEDKVRQLEQEKASMVKLNNQLQQESD 1335 Query: 549 -KVSDSNKEIVRLT-EELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMI-EM 605 K+ D EI L E+ L K+ E+EE ++L D D + ++ + I E+ Sbjct: 1336 EKLLDKENEIAHLNLEKKQILDSKLQEIEE---IVKLQQQDKDISLQKQELIFNERIKEL 1392 Query: 606 ENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLE 665 E L + + ++ +Q + K +E E+K++D+ + Q ++ I++ + Sbjct: 1393 EELVQQAISEKEIIITQ----------YEDKNNEKENKISDLLK-QIEEQSQNIQNQN-- 1439 Query: 666 EQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLE 725 E+ID+L+ L I + +K++ Y E + ++ + ++ Y +E +L LE Sbjct: 1440 EEIDSLNQQVILLRQKISQKEKEKQENY------ERESKEKQDLIEKYAEEKQNLQISLE 1493 Query: 726 KMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESI 785 + K ++ +I ++ Q ++I+++++ IE ++++ I L+ I Sbjct: 1494 NRFSVKQKQMEEQIKSYQEQLSNEQEAHQSQIEQKEMIIE-------EHQNIIDELKTEI 1546 Query: 786 AVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIE 845 ++ +RY + +QL Y Q+ E NRL V + +E EI Sbjct: 1547 EGLKTQRYEKLSEQEQL-------------YENQQQE--NRLLV-----KQIENLKKEIV 1586 Query: 846 HENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLES 905 +++++L + + E Q + + +++ + + K + E+ + Q+ +L+ Sbjct: 1587 NKSEQLIAEREEQQETQQQFDMQIKQIEEKSSQEINKIQQESQEAIETA--EKQILELKR 1644 Query: 906 NLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEK----NIEYVTQLE 961 L++I + + + Q K +E ++ + + ++++ L +K E+ + + +L+ Sbjct: 1645 QLEKIIKQKEEELQQANKLVEQVKEQLLQEKNQSVKENNNLIQKIEQQQQLQLRELNELK 1704 Query: 962 AQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINE-INKLNALLKQ 1020 Q ++ EN N V + NL+ ++++Q S + E+ N+ + K L Q Sbjct: 1705 EQNKQILAEAEN-NQLVFNQTEANLQEQIAYLKQQLDISNNKLEEEHNKFLQKFTNL--Q 1761 Query: 1021 KDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEE 1080 K+ E Q + N + ++ E L + E E+ +++LL KQ EE Sbjct: 1762 KEAEQNTQKQVLLNEALRDEKWKAEKEQILHSHKMTISQKENELFEKNQELLQMKQQLEE 1821 Query: 1081 LQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXX 1140 + L ++KE++E+ + ++ T+ I + ++ ++ + N++ Sbjct: 1822 FKSLSHTYQTKLKEIQES--NEKQSVINTQ--IFTKQLDQVNTEKNSLKQNLENLNAKLQ 1877 Query: 1141 XLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLK 1200 K +E ++ I + ++ +L QE TKIIQL + + ++I Q K Sbjct: 1878 E-KAEETQKLIVQNGEYLTKAHQLEQLNQEKETKIIQLSKNIQQQDTYIQKTAQEIQQKK 1936 Query: 1201 SKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQ 1260 ++ LN E ++ +L+ IS Q L KQ + ++ + ++ E + + Sbjct: 1937 DIIQTLNEEYSKVIQQNEQLKHQISETQTQ-------LEKQSIIHKQKEVERLELVHKSK 1989 Query: 1261 LSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQI 1320 L E+K+ + L+ + EE + + +EQ L+ + Q K+ + L KYA+ I+ Sbjct: 1990 LEELENKHNEELNKI----FEE--RRIMLEQ---LEEQKQQKDSEIEELCLKYAEEIDNF 2040 Query: 1321 EILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQS--------YKQMQEQSILNINE 1372 + L ++++ L Q Y Q + + ++ +N+ Sbjct: 2041 KKLTKNLQNQNEFLEKENAEKEELCNQFQVALNEFKQELNKRDELLYIQEEYEKLVEVNK 2100 Query: 1373 --ENAQLKKSSXXXXXXXXXXXXRVNDAEAKVL--ELTHQLELKDSEI---YQKTHEYTI 1425 EN KK+ + + E K + + +++++ +E+ Y++T + Sbjct: 2101 ILENDLEKKTKMIEESKVNLIQAKRDMQEMKKILDQKNKEIDVQKNELKEFYERTQVFAQ 2160 Query: 1426 TLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERV 1485 T + E ++ +L++ +I E+ ++ L++++ + A E Q EI ++ Sbjct: 2161 TRDKDVKEVKDQYCKLLDEHNKIMSQYNEQSEKMDKLKVEISDYAK--EKAQINQEIRKL 2218 Query: 1486 KLIE-ELNVKITESVSLNKQVAELNKALEEE 1515 + E +L ++ + + +NK++ E NK LEE+ Sbjct: 2219 QSNEKKLKQQLNDMIEVNKRLNEDNKKLEED 2249 Score = 132 bits (318), Expect = 1e-28 Identities = 228/1190 (19%), Positives = 510/1190 (42%), Gaps = 95/1190 (7%) Query: 449 IAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSA 508 + Q LE Q +E ++G + + + K E+ +Q + + +I+ ++ Sbjct: 465 LCQHYLEQAQELELKMNYNMGKTKDQLMHLMKYVEKFQQN------EYQYRSIIKLQRAK 518 Query: 509 EEQITQLNDEIDAANKNMIK--VKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHH 566 E++ E+ NK + K V+ ++ QK ++N ++ ++ +L +E Sbjct: 519 IERV-----ELMLKNKQLTKEQVQEFFNEDREKTQKELNNLRELLENQMYCAKLLDENVE 573 Query: 567 LSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDL 626 L Q+V +++E ++ L + + +++S K +E + L ES+K Sbjct: 574 LQQQVEKIQEPGRSIFQQLTN--NVDVLKSIQNKLEQNIEQRVRLQKVVEDLEESKKNAS 631 Query: 627 VQELHILQQKYDEVE-DKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENL 685 L+ + ++E + + + L S+ + + K E ID + + L+ +E + Sbjct: 632 PDRSKKLEFQLTQIEKEHKSAVENLNSELLTQKQKLNDQERMIDQIVEENQMLSKELEQM 691 Query: 686 KLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINH-EEQ 744 KL +E K ++ E+ +++L+ I E ++TD++ + + +L+ +I ++Q Sbjct: 692 KLMQE-----FKQAQH--EETVHQLKKLIAEKSNVTDEMNQELRLRNIDLVEQIKQLQQQ 744 Query: 745 SKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGS 804 + + + +++ Q +D+ E ++ KY + + E L+ +L S Sbjct: 745 NLLLNERSKESEKQRQDMAEEKKQAH-EKYLKYLEKYNEETT-------HLQASIQELTS 796 Query: 805 YLQEKQ---KAYSEYTIQEDELVNRLAVLMDHDRVVEKQLL-EIEHENKELQKKNQILLE 860 EK+ + IQ +E + L + + V+ L EIE + ++++ + L+E Sbjct: 797 NFNEKEFENLRIKDEVIQGNERIRELESNISQAKQVQDSLQQEIEQKKNQIEQLEEQLIE 856 Query: 861 ENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQ 920 + D+Q+ L E N + E K +TQL + L+ + + L+ Sbjct: 857 LEE-ADNQRKDLQEEIETLNETLNFRENELEEMKKQKTQLLNQIQELQAAKVQIEELVQT 915 Query: 921 KKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEE 980 K IE+LE + N Q + +K E+ +K + +E +L E + E N+ ++ Sbjct: 916 LKMRIEELESQNNEQNNKLLEEKV---EEVKKLEDEKVVIEQELNEIRKTKEADNIVIQ- 971 Query: 981 LNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDE-EIIALNQKINNAQVSY 1039 NK LE I K Q + +Q INEI+ + Q E EI L +K+ Sbjct: 972 -NK--LEQI-----KSLEQEKVFVQQKINEISDEKERITQVLEGEIKILKEKLLLEDDQN 1023 Query: 1040 MSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETK 1099 +++ ++++ Q ++++ ++ +Q+ + +NE+ ++ +++ KE +ET Sbjct: 1024 QEVINQKQTEIEQLRSQVQQLKSSIQKEIESF-----NNEKTKL----EENFKKEKQETL 1074 Query: 1100 LTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQE 1159 L + ++ + + + + + + Q +EE QE L+E Sbjct: 1075 LQCKRDLQEQCEQLQQNFSIELEKQIEIREKKIAKLEEEKSKVIQQSQEETQQELETLKE 1134 Query: 1160 QSAKLNTELQECYTKIIQ--LETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTV 1217 + + E + IQ +E + EL G Q+ + Q++ +++ +++ + Sbjct: 1135 DLERQVVLITEQKDQEIQQIIEKNSEELQGLLNEKQQLLKQIQLNKDEIQMHQNSIQAYE 1194 Query: 1218 AELRSSISSAVDQRGFEIAE--LWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSV 1275 +++ SS +++ G I + +K+ ++ + +L+ + + K QL +S+ Sbjct: 1195 QQIQELESSLIEKEGLYIEKNNAFKEQQSKLR-HLESESSQLKEEAQELKDKASQLAESL 1253 Query: 1276 QSSTQEETNKIVTME----QVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEK 1331 + TQ + +E ++ Q K+ +E ++ L+E+ + +Q E E+ED+ Sbjct: 1254 EGQTQAYSKAKAEVEKLQNEILYQQEKILQQENTIKILKERQQEESSQSEKYVYELEDK- 1312 Query: 1332 VAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXX 1391 L+ E+ +E I ++N E Q+ S Sbjct: 1313 ---VRQLEQEKASMVKLNNQLQQESDEKLLDKENEIAHLNLEKKQILDSKLQEIEEIVKL 1369 Query: 1392 XXRVNDAEAKVLELTHQLELKDSE--IYQKTHEYTITLTQ---RNDEFEN----VRQQLV 1442 + D + EL +K+ E + Q E I +TQ +N+E EN + +Q+ Sbjct: 1370 QQQDKDISLQKQELIFNERIKELEELVQQAISEKEIIITQYEDKNNEKENKISDLLKQIE 1429 Query: 1443 EYEKRIEDLTYEKES---ELAILRLKM----HENANHYETMQKESEIERVKLIEE---LN 1492 E + I++ E +S ++ +LR K+ E +YE KE + K EE L Sbjct: 1430 EQSQNIQNQNEEIDSLNQQVILLRQKISQKEKEKQENYERESKEKQDLIEKYAEEKQNLQ 1489 Query: 1493 VKITESVSL-NKQVAELNKALEEEVAKTNEM-QTALENQEIEIVTLNDEITNLQNMVRAS 1550 + + S+ KQ+ E K+ +E+++ E Q+ +E +E+ I + I L+ + Sbjct: 1490 ISLENRFSVKQKQMEEQIKSYQEQLSNEQEAHQSQIEQKEMIIEEHQNIIDELKTEI--E 1547 Query: 1551 SSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDLAMYMLHQRD 1600 K Q++ + + ++Q +N + + ++ + + ++ + ++ +R+ Sbjct: 1548 GLKTQRYEKLSEQEQLYENQQQENRLLVKQIENLKKEIVNKSEQLIAERE 1597 Score = 124 bits (300), Expect = 2e-26 Identities = 216/1108 (19%), Positives = 490/1108 (44%), Gaps = 119/1108 (10%) Query: 153 EKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXE 212 +K+N ++ L ++ K ILD K+ E ++I++ + + E Sbjct: 1340 DKENEIAHLNLEKK----QILD--SKLQEIEEIVKLQQQDKDISLQKQELIFNERIKELE 1393 Query: 213 DTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESK-DVRISSLEEANKLLEAARFEISLEH 271 + QQ +E I + +EK+ + D+ + + + +++ N+ +++ ++ L Sbjct: 1394 ELVQQAISEKEIIITQYEDKNNEKENKISDLLKQIEEQSQNIQNQNEEIDSLNQQVILLR 1453 Query: 272 SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELL 331 K++Q+ ++ +++ E +EK ++ EK + E N+ +I L Sbjct: 1454 QKISQKEKEK---------------QENYERESKEKQDLIEKYAEEKQNL-----QISLE 1493 Query: 332 EHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSS 391 + + +Q +++++ + E +A S ++ +I +N ++K+ L + Sbjct: 1494 NRFSVKQKQMEEQIKSYQEQLSNEQEAHQSQIEQKEMIIEEH--QNIIDELKTEIEGLKT 1551 Query: 392 ---ETLNQDTDKKINKNEIAKLEMV-IQSLNKDLVDK-EYVISEKDTXXXXXXXXXXGKD 446 E L++ N+ + +L + I++L K++V+K E +I+E++ D Sbjct: 1552 QRYEKLSEQEQLYENQQQENRLLVKQIENLKKEIVNKSEQLIAEREEQQETQQQF----D 1607 Query: 447 TLIAQLQLEHQQHM---EGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIE 503 I Q++ + Q + + S + T + + E+ + E++ ++ +E++ N L+E Sbjct: 1608 MQIKQIEEKSSQEINKIQQESQEAIETAEKQILELKRQLEKIIKQKEEELQQAN--KLVE 1665 Query: 504 KLKSAEEQITQLNDEIDAANKNMI-KVKSNHKLKLKQMQKTIDNFSKV---SDSNKEIVR 559 ++K EQ+ Q ++ N N+I K++ +L+L+++ + + ++ +++N+ + Sbjct: 1666 QVK---EQLLQEKNQSVKENNNLIQKIEQQQQLQLRELNELKEQNKQILAEAENNQLVFN 1722 Query: 560 LTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDV-YKKMIEMENLAETRLKAISL 618 TE +L +++A L+++ ++ + ++ + + ++ +K E + L Sbjct: 1723 QTEA--NLQEQIAYLKQQL-DISNNKLEEEHNKFLQKFTNLQKEAEQNTQKQVLLNEALR 1779 Query: 619 LESQKFDLVQELHILQQKYDEVEDKLADISQ--LQSDQVCSEIKSVHLEEQIDALSASKK 676 E K + Q LH + + E++L + +Q LQ Q E KS+ Q + Sbjct: 1780 DEKWKAEKEQILHSHKMTISQKENELFEKNQELLQMKQQLEEFKSLSHTYQTKLKEIQES 1839 Query: 677 ELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISEL- 735 + N ++ +QL + + K+++ N L +QE + T KL + E +++ Sbjct: 1840 NEKQSVINTQIFTKQLDQVNTEKNSLKQNLEN-LNAKLQEKAEETQKLIVQNGEYLTKAH 1898 Query: 736 -LAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYS 794 L ++N E+++KI + IQ++D YI+ E+ + K I L E + + + Sbjct: 1899 QLEQLNQEKETKI---IQLSKNIQQQDTYIQKTAQEIQQKKDIIQTLNEEYSKVIQQNEQ 1955 Query: 795 LERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKK 854 L+ + + + L EKQ I + + V RL +V K LE E ENK ++ Sbjct: 1956 LKHQISETQTQL-EKQSI-----IHKQKEVERL-------ELVHKSKLE-ELENKHNEEL 2001 Query: 855 NQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQ-LRDLESNLKRITHE 913 N+I EE + + L + +Q ++ +E+ E ++ K T+ L++ L++ E Sbjct: 2002 NKIF-EERRIMLEQLEEQKQQKDSEIEELCLKYAEEIDNFKKLTKNLQNQNEFLEKENAE 2060 Query: 914 HQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIEN 973 + L Q + + + + E N + E + E+YEK +E LE L++ IE Sbjct: 2061 KEELCNQFQVALNEFKQELNKRDELLY-----IQEEYEKLVEVNKILENDLEKKTKMIEE 2115 Query: 974 LNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKIN 1033 +N+ + + E+ K + Q+ + D + + E + + Q ++ + Sbjct: 2116 SKVNLIQAKRDMQEM--KKILDQKNKEIDVQKNELKEFYERTQVFAQTRDK------DVK 2167 Query: 1034 NAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIK 1093 + Y ++ ++ ++Q+ + E M++ +S + Q N+E +R+ K Sbjct: 2168 EVKDQYCKLLDEHNKIMSQYNEQSEKMDKLKVEISDYAKEKAQINQE----IRKLQSNEK 2223 Query: 1094 ELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQE 1153 +LK+ +L + + K ++ + + +D NV ++ I+ Sbjct: 2224 KLKQ-QLNDMIEVNKR----LNEDNKKLEEDYENVQRELQYIGGH------NNPDQKIKM 2272 Query: 1154 RSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNL 1213 + ++E++ L E +E T++ Q+ N +L +QI QL++ N + N Sbjct: 2273 FNKIKEENTLLKNEKKELSTQLAQIAEENKQLL-------KQIEQLRT-----NPDRSNP 2320 Query: 1214 LSTVAELRSSISSAVDQRGFEIAELWKQ 1241 L + R SS+ + ++ EL KQ Sbjct: 2321 LKNIGNQRFGNSSSSTDKSIQM-ELEKQ 2347 Score = 113 bits (271), Expect = 5e-23 Identities = 182/936 (19%), Positives = 401/936 (42%), Gaps = 82/936 (8%) Query: 151 IKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXX 210 I+E N + L+ +++ ++T EK++E++Q+ E + + Sbjct: 1532 IEEHQNIIDELKTEIEGLKT---QRYEKLSEQEQLYENQQQENRLLVKQI---------- 1578 Query: 211 XEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLE 270 E+ K+++ E IA E ++ +Q+ D++ K + S +E NK+ + ++ I Sbjct: 1579 -ENLKKEIVNKSEQLIAEREEQQETQQQF--DMQIKQIEEKSSQEINKIQQESQEAIETA 1635 Query: 271 HSK---LAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKK 327 + L ++LE+ L +Q E +EK + ++ + + E ++ Sbjct: 1636 EKQILELKRQLEKIIKQKEEELQQANKLVEQVKEQLLQEKNQSVKENN-NLIQKIEQQQQ 1694 Query: 328 IELLEHLNCQIRQTNKEL-----ENKLATMGTESKAVSSPSKKGSPL-ISRKSGRNTASK 381 ++L E LN ++++ NK++ N+L TE+ + L IS +K Sbjct: 1695 LQLRE-LN-ELKEQNKQILAEAENNQLVFNQTEANLQEQIAYLKQQLDISNNKLEEEHNK 1752 Query: 382 MKSPWSQLSSETLNQDTDKKINKNEI-------AKLEMVIQSLNKDLVDKEYVISEKDTX 434 ++ L E Q+T K++ NE A+ E ++ S + KE + EK+ Sbjct: 1753 FLQKFTNLQKEA-EQNTQKQVLLNEALRDEKWKAEKEQILHSHKMTISQKENELFEKNQE 1811 Query: 435 XXXXXXXXXGKDTLIAQLQL---EHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELND 491 +L Q E Q+ E S+I+ T+ ++++ + LKQ L + Sbjct: 1812 LLQMKQQLEEFKSLSHTYQTKLKEIQESNEKQSVINTQIFTKQLDQVNTEKNSLKQNLEN 1871 Query: 492 -----EIKDVNVKDLI----EKLKSAEEQITQLNDE----IDAANKNMIKVKSNHKLKLK 538 + K + LI E L A Q+ QLN E I +KN+ + + + + Sbjct: 1872 LNAKLQEKAEETQKLIVQNGEYLTKAH-QLEQLNQEKETKIIQLSKNIQQQDTYIQKTAQ 1930 Query: 539 QMQKTIDNFSKVSDSNKEIVRLTEEL-HHLSQKVAELEEEK---GNLQLHLVDYDSGRMI 594 ++Q+ D +++ ++++ E+L H +S+ +LE++ ++ ++ + Sbjct: 1931 EIQQKKDIIQTLNEEYSKVIQQNEQLKHQISETQTQLEKQSIIHKQKEVERLELVHKSKL 1990 Query: 595 ESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQ-LQSD 653 E K E+ + E R + LE QK E+ L KY E D +++ LQ+ Sbjct: 1991 EELENKHNEELNKIFEERRIMLEQLEEQKQQKDSEIEELCLKYAEEIDNFKKLTKNLQNQ 2050 Query: 654 QVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNY 713 E ++ EE + + E + L E LY ++ + E ++ N Sbjct: 2051 NEFLEKENAEKEELCNQFQVALNEFK---QELNKRDELLY-----IQEEYEKLVEV--NK 2100 Query: 714 IQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDL--YIENIESEL 771 I EN DL K + + K++ + AK + +E KI Q + +Q+ +L + E + Sbjct: 2101 ILEN-DLEKKTKMIEESKVNLIQAKRDMQEMKKILDQKNKEIDVQKNELKEFYERTQVFA 2159 Query: 772 SKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLM 831 + +++ + D + + ++ + + + S+Y ++ ++ + L Sbjct: 2160 QTRDKDVKEVKDQYCKLLDEHNKIMSQYNEQSEKMDKLKVEISDYAKEKAQINQEIRKLQ 2219 Query: 832 DHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAES 891 +++ +++QL ++ NK L + N+ L E+ +N+Q L + H N +K + + Sbjct: 2220 SNEKKLKQQLNDMIEVNKRLNEDNKKLEEDYENVQRELQYIGGHNNP-DQKIKMFNKIKE 2278 Query: 892 ESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYE 951 E+T + + ++L + L +I E++ L+ K+IE L T + + K + N+++ Sbjct: 2279 ENTLLKNEKKELSTQLAQIAEENKQLL----KQIEQL----RTNPDRSNPLKNIGNQRFG 2330 Query: 952 KNIEYVTQ-LEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINE 1010 + + ++ +L++ N + L + + N++ +++ +Q Q I+ Sbjct: 2331 NSSSSTDKSIQMELEKQINENKKLQDIIIQTNQI-IQMGQSSKGLKQFQKSSLDRDLISG 2389 Query: 1011 INKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDY 1046 + ++ + K+ +I L +++ + Y + Y Sbjct: 2390 VKQIVQEILDKENKIKNLTGELDAKTIKYTELEKKY 2425 Score = 97.9 bits (233), Expect = 2e-18 Identities = 198/995 (19%), Positives = 416/995 (41%), Gaps = 107/995 (10%) Query: 49 ERQIKFERAQKCLENAALVS-KRIKEHRKATAELLGRPFVPGISESLANTLKQKEILMEK 107 E Q +F+ K +E + +I++ + E + + + L +KQKE +++ Sbjct: 1601 ETQQQFDMQIKQIEEKSSQEINKIQQESQEAIETAEKQILE-LKRQLEKIIKQKEEELQQ 1659 Query: 108 ----IKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNALSVLQV 163 ++Q KE + V+ QL ++ L K+ L+ + Sbjct: 1660 ANKLVEQVKEQLLQEKNQSVKENNNLIQKIEQQQQLQLRELNELKEQNKQ---ILAEAEN 1716 Query: 164 KMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQE 223 + T +LQE+I Q ++ N E Q+ + E Sbjct: 1717 NQLVFNQTEANLQEQIAYLKQQLDISNNKLEEEHNKFLQKFTNLQKEAEQNTQKQVLLNE 1776 Query: 224 NFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXX 283 + +WK EK+++L S + IS E N+L FE + E ++ Q+LE+ Sbjct: 1777 AL--RDEKWKAEKEQIL---HSHKMTISQKE--NEL-----FEKNQELLQMKQQLEEFKS 1824 Query: 284 XXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNK 343 + + +E E EK S + N TK+++ + ++Q + Sbjct: 1825 LS------------HTYQTKLKEIQESNEKQS--VINTQIFTKQLDQVNTEKNSLKQNLE 1870 Query: 344 ELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKIN 403 L KL E++ + + G L + ++ QLS QDT + Sbjct: 1871 NLNAKLQEKAEETQKLIV--QNGEYLTKAHQLEQLNQEKETKIIQLSKNIQQQDTYIQKT 1928 Query: 404 KNEIAKLEMVIQSLNKD---LVDKEYVISEK--DTXXXXXXXXXXGKDTLIAQLQLEHQQ 458 EI + + +IQ+LN++ ++ + + + +T K + +L+L H+ Sbjct: 1929 AQEIQQKKDIIQTLNEEYSKVIQQNEQLKHQISETQTQLEKQSIIHKQKEVERLELVHKS 1988 Query: 459 HMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEI--KDVNVKDLIEKLKSAEEQITQLN 516 +E H E++N+I + + + ++L ++ KD +++L K + +L Sbjct: 1989 KLEELENKH----NEELNKIFEERRIMLEQLEEQKQQKDSEIEELCLKYAEEIDNFKKLT 2044 Query: 517 DEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQ--KVAEL 574 + N+ + K + + Q Q ++ F + + E++ + EE L + K+ E Sbjct: 2045 KNLQNQNEFLEKENAEKEELCNQFQVALNEFKQELNKRDELLYIQEEYEKLVEVNKILEN 2104 Query: 575 EEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQ 634 + EK + +++ +I++ + M EM+ + + + K I + QK +L +E + Sbjct: 2105 DLEK---KTKMIEESKVNLIQAK--RDMQEMKKILDQKNKEIDV---QKNEL-KEFYERT 2155 Query: 635 QKYDEVEDKLADISQLQSDQVCSEIKSVH-LEEQIDALSASKKELALVIENLKLDKEQLY 693 Q + + DK D+ +++ DQ C + + + Q + S +L + I + +K Q+ Sbjct: 2156 QVFAQTRDK--DVKEVK-DQYCKLLDEHNKIMSQYNEQSEKMDKLKVEISDYAKEKAQIN 2212 Query: 694 GTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSA--EKISELLAKIN-HEEQSKIQTQ 750 I+ L+++++ + +L + I+ N L + +K+ E + L I H + Sbjct: 2213 QEIRKLQSNEKKLKQQLNDMIEVNKRLNEDNKKLEEDYENVQRELQYIGGHNNPDQKIKM 2272 Query: 751 FGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQ 810 F KI+E + ++N + ELS ++I EE+ +++ L D+ Sbjct: 2273 FN---KIKEENTLLKNEKKELSTQLAQIA--EENKQLLKQIE-QLRTNPDRSNPLKNIGN 2326 Query: 811 KAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLS 870 + + + D+ ++ M+ +EKQ+ +ENK+LQ I+++ NQ +Q+ S Sbjct: 2327 QRFGNSSSSTDK-----SIQME----LEKQI----NENKKLQ---DIIIQTNQIIQMGQS 2370 Query: 871 D--MQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIED- 927 ++Q + +++ DL Q ++ D E+ +K +T E + K E+E Sbjct: 2371 SKGLKQFQKSSLDR----DLISGVKQIVQ-EILDKENKIKNLTGELDAKTI-KYTELEKK 2424 Query: 928 -LEIEFNTQIESAIRD--KKVLNEKY------EKNIEYVTQLEAQLQEYKN-NIENLNMN 977 L+++ N + S + + ++ +++ +I+ Q Q Y+N N N N+N Sbjct: 2425 YLQLQLNVKDSSYLNNINRERSKDRFGAALGSNSSIQQQQQPLQQPMSYQNLNHLNQNIN 2484 Query: 978 VEELNKMNLELIDKHVQKQQTQSPDYTEQYINEIN 1012 ++ + + I +H +Q Q P+ Y N N Sbjct: 2485 LQNYSIQQQQQIQQHQAQQNQQKPNRLNFYNNYNN 2519 Score = 70.1 bits (164), Expect = 5e-10 Identities = 152/785 (19%), Positives = 321/785 (40%), Gaps = 75/785 (9%) Query: 859 LEENQNLQISLSDMQQHYNALVEKAN-RTDLAESESTKYQTQLRD-LESNLK-RITHEHQ 915 L+E N+ SLS + NALVE N R +K L+D L N K R+ Sbjct: 304 LKEGCNINKSLSILGNVINALVEVDNGRARHIHYRDSKLTFFLKDSLGGNSKTRVIANIS 363 Query: 916 TLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVT------QLE-AQLQE-- 966 ++ + L+ ++ I++K +NE + N+E + +LE Q +E Sbjct: 364 PASSAFQETLSTLKFAKRAKL---IKNKVQINEDHSGNVESLNNEIKKLRLENLQFRELL 420 Query: 967 ----------YKNNIENLNMNVEELNKMNLELI-DKHVQKQQTQS--PDYTEQYINEINK 1013 NN + + ++ E K NL +I D++++ Q+T+ Y EQ K Sbjct: 421 LKGGSIPSFFQPNNSQPQSPSIRE-QKNNLRMIKDENIKMQETEELCQHYLEQAQELELK 479 Query: 1014 LNALL-KQKDE--EIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQ 1070 +N + K KD+ ++ +K + Y S++ +K+ + L+N + ++V + Sbjct: 480 MNYNMGKTKDQLMHLMKYVEKFQQNEYQYRSIIKLQRAKIERVELMLKNKQLTKEQVQEF 539 Query: 1071 LLDSKQHNE-ELQILVREQDDQI--KELKETKLTFEMNIPKTE--GMIISSTIEPMSDDA 1125 + ++ + EL L ++Q+ +L + + + + K + G I + D Sbjct: 540 FNEDREKTQKELNNLRELLENQMYCAKLLDENVELQQQVEKIQEPGRSIFQQLTNNVDVL 599 Query: 1126 NNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTK-IIQLETLNTE 1184 ++ L+ E+ +++ ++S KL +L + + +E LN+E Sbjct: 600 KSIQNKLEQNIEQRVRLQKVVEDLEESKKNASPDRSKKLEFQLTQIEKEHKSAVENLNSE 659 Query: 1185 LTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLA 1244 L + ++++N + ++Q+ EN +LS E + + E K+ +A Sbjct: 660 L----LTQKQKLNDQERMIDQIVEEN-QMLSKELEQMKLMQEFKQAQHEETVHQLKKLIA 714 Query: 1245 QREADFQKTEHELRVQLSAFESKYEQLLD--------SVQSSTQEE---TNKIVTMEQVT 1293 ++ + ELR++ + +QL S +S Q + K E+ Sbjct: 715 EKSNVTDEMNQELRLRNIDLVEQIKQLQQQNLLLNERSKESEKQRQDMAEEKKQAHEKYL 774 Query: 1294 SLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKV-------AFXXXXXXXXXXXX 1346 K ++ HL+ ++ N+ E I+DE + Sbjct: 775 KYLEKYNEETTHLQASIQELTSNFNEKEFENLRIKDEVIQGNERIRELESNISQAKQVQD 834 Query: 1347 XXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELT 1406 ++ + +Q++EQ ++ + E + Q K R N+ E + T Sbjct: 835 SLQQEIEQKKNQIEQLEEQ-LIELEEADNQRKDLQEEIETLNETLNFRENELEEMKKQKT 893 Query: 1407 HQL----ELKDSEIYQKTHEYTITLTQRNDEFE--NVRQQLVEYEKRIEDLTYEKESELA 1460 L EL+ +++ + E TL R +E E N Q E+++E++ + E E Sbjct: 894 QLLNQIQELQAAKV--QIEELVQTLKMRIEELESQNNEQNNKLLEEKVEEVK-KLEDEKV 950 Query: 1461 ILRLKMHE--NANHYETMQKESEIERVKLIEELNVKITESVS-LNKQVAELNKALEEEVA 1517 ++ +++E + + ++++E++K +E+ V + + ++ ++ + + + LE E+ Sbjct: 951 VIEQELNEIRKTKEADNIVIQNKLEQIKSLEQEKVFVQQKINEISDEKERITQVLEGEIK 1010 Query: 1518 KTNEMQTALENQEIEIVTLND-EITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTM 1576 E ++Q E++ EI L++ V+ S IQK + ++ K +E Sbjct: 1011 ILKEKLLLEDDQNQEVINQKQTEIEQLRSQVQQLKSSIQKEIESFNNEKTKLEENFKKEK 1070 Query: 1577 NKELL 1581 + LL Sbjct: 1071 QETLL 1075 >UniRef50_UPI00006CD2DD Cluster: Viral A-type inclusion protein repeat containing protein; n=1; Tetrahymena thermophila SB210|Rep: Viral A-type inclusion protein repeat containing protein - Tetrahymena thermophila SB210 Length = 1379 Score = 172 bits (419), Expect = 6e-41 Identities = 234/1153 (20%), Positives = 508/1153 (44%), Gaps = 108/1153 (9%) Query: 468 VGTNTEDVNEIAKVQEQLKQEL-NDEIKDVNVKDLIEKL-KSAEEQITQLNDEIDAANKN 525 + N V ++ + E+LK + N E KD E+L K ++ I + + + Sbjct: 64 IENNQTIVKKVGNLAEELKVKFANLETDYDQCKDEKEELEKKYKQSIEKYGEMMKNYEHQ 123 Query: 526 MIKVKSNHKLKLKQMQKTIDNFSKVSDSNKE-IVRLTEELHHLSQKVAELEEEKGNLQLH 584 +I +++ + ++++Q+Q+ ID K ++ ++ + + +++ Q +++ + + H Sbjct: 124 IISLENENNIRIQQLQQQIDELKKQNEEKEQSYLNMQQQIKQDKQSFDDIQNKYEEINKH 183 Query: 585 LVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHIL---QQKYDEVE 641 + + + SD + K++ + + K D+ + HI+ QQ + ++ Sbjct: 184 --NQEQFKQ-NSDQWVKLVNLTEEVIFNFYNSNFFTENKDDISSQTHIILQHQQTFQQLI 240 Query: 642 DK----LADISQLQ---SDQVCSEIKSVH------LEEQIDALSASKKELALVIENLKLD 688 +K LA+ + SD+ ++IKS + +++ L + L + Sbjct: 241 EKYVTFLAEQKEKNEAISDEAFNKIKSENGNGVQKTNQRVQDLQQKFEAYQQQFNKLNSE 300 Query: 689 KEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQ 748 ++ +++ + ED+ N+L N + +L ++ +K E I +L +I +Q + Sbjct: 301 SQENETKLQETKKQLEDLQNELGNKNNQIQELNEQHQKSQTE-IQKLNEQITSNQQRIEE 359 Query: 749 TQFGIDAKIQERDLYIENIESELSKYKSRI---CRLEESIAVMEDRRYSLERKADQLGSY 805 Q + + E+D I I+ +LS +I ++ + + LE+ +Q S Sbjct: 360 LQKNENILV-EKDKNINEIKEQLSALNQQIEGFKDIQNKLDTKTEEFEKLEKDFNQQKSE 418 Query: 806 LQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNL 865 L+EK K+ E + + L ++ +++ + +KQL ++ N LQ N+ EN+ L Sbjct: 419 LEEKIKSKDE---EIENLSKKIQDIVEQQQEKQKQLDDL---NSNLQNSNK----ENEQL 468 Query: 866 QISLSDMQQHYN-ALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKE 924 + ++D + N + ++ +++ ++E + Q QL D + ++ E + L K++ Sbjct: 469 KQEINDFKNKINNSNQDQEQQSNQLKAELKQTQEQLNDSQQKFEQADKELKDL----KQQ 524 Query: 925 IEDLEIEFNTQIESA--IRDK-KVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEEL 981 IED +++ N + + + ++D+ K NEK ++ + + Q++ + K N +L V+E Sbjct: 525 IEDEKVKLNDKSQESENLKDQLKSANEKLNESQQKLEQIQKNFDDLKQN-NDLQKIVDE- 582 Query: 982 NKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMS 1041 + E +++ +++ +TQ EQ ++ +LN +K+E NQ + + Sbjct: 583 KQQKCEELERELKELKTQQ----EQVTAQVQQLNV---EKEEIQTKFNQ-VEQEKEQLKK 634 Query: 1042 MVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKET--K 1099 + L+Q + EN E+E+ + + + + ++ ++QI +E+D Q+ + K T Sbjct: 635 QEQEKIDLLSQAKQEKENNEQEINNLKQTIANLEKERTDIQIQSQEKDKQLDDAKHTLEN 694 Query: 1100 LTFEMNIPKTEGMIISSTIEP---MSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSV 1156 L E+ K + I E + + + L + E E +++ Sbjct: 695 LNKEIEQLKNQNQAIGDVNEKNKQLESEITQIKSEIEQKNTEIQSLNSKNETEISEKKQQ 754 Query: 1157 LQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLST 1216 L++ + ++N +L E +I QL T N L NQ N ++KL LN+E + Sbjct: 755 LEDHTKQVN-QLNE---QIHQLSTENENLKNEIQTNQ---NISQTKLTDLNSEIEGFQKE 807 Query: 1217 VAELRSSISSAVDQ-RGFEIA-ELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDS 1274 + E + + Q +G ++ E ++ L ++ + QK +L+ ES EQ ++ Sbjct: 808 IEETKLQLDDKNTQLKGLQVKLEALEKQLLEKNEEIQKVNQQLK------ES--EQKHEA 859 Query: 1275 VQSSTQEETNKIVTMEQVTSLQNKLQ-DKEEHLRNLQEKYADVINQIEILRSEIEDEKVA 1333 +Q +E N + T+E+ N++Q D + + +L++K D+ Q++ EI K Sbjct: 860 IQKQNEELQNSLKTLEEKD--YNQIQNDLNQQVSDLKQKEQDLNKQLDQKLQEINQIKQQ 917 Query: 1334 FXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXX 1393 ++ NQ+ Q QEQ I I + Q ++ Sbjct: 918 LSNETSDFMKKNVQLQQTIQQLNQTISQYQEQ-IERIKTDLYQSQQEKSQLQSKLNEANR 976 Query: 1394 RVNDAEA---KVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIED 1450 + + E K +E+ +LE + ++ H Y + + E +V + +++ K + Sbjct: 977 EIQNKEDDLNKKVEIIAELEQNNKDLKINLHNYEVKSYDLDKERFDVLEIQIQHNKE-QQ 1035 Query: 1451 LTYEKESELAILRLK------MHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQ 1504 + Y K++E I +L+ + + + E +QKE + E+V + EE++ K ++ Sbjct: 1036 VQY-KQAEEKIQKLEEEIKKLLADKTDSLEKLQKEIKTEQV-IGEEMSKKFRSNL----- 1088 Query: 1505 VAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDT 1564 AEL + N Q +LEN + I L + + SS+KI + D Sbjct: 1089 -AEL---------QINNEQNSLENSQKTINQLAEVVLRKVKDCFYSSTKIVQISRLFYDG 1138 Query: 1565 KQGRDEQLDNTMN 1577 GR+ DN ++ Sbjct: 1139 SDGRNASQDNALS 1151 Score = 170 bits (414), Expect = 2e-40 Identities = 232/1035 (22%), Positives = 453/1035 (43%), Gaps = 76/1035 (7%) Query: 583 LHLVDYDSGRMIESD--VYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEV 640 + + D D+ IE++ + KK+ NLAE + LE+ E L++KY + Sbjct: 53 IEITDEDNDPEIENNQTIVKKV---GNLAEELKVKFANLETDYDQCKDEKEELEKKYKQS 109 Query: 641 EDKLADISQLQSDQVCS-----EIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGT 695 +K ++ + Q+ S I+ L++QID L +E N++ +Q + Sbjct: 110 IEKYGEMMKNYEHQIISLENENNIRIQQLQQQIDELKKQNEEKEQSYLNMQQQIKQDKQS 169 Query: 696 IKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELL-AKINHEEQSKIQTQFGID 754 D++N E+I Q ++N D KL ++ E I + E + I +Q I Sbjct: 170 FDDIQNKYEEINKHNQEQFKQNSDQWVKLVNLTEEVIFNFYNSNFFTENKDDISSQTHII 229 Query: 755 AKIQER-DLYIENIESELSKYKSRICRL-EESIAVMEDRRYSLERKADQLGSYLQEKQKA 812 + Q+ IE + L++ K + + +E+ ++ + +K +Q LQ+K +A Sbjct: 230 LQHQQTFQQLIEKYVTFLAEQKEKNEAISDEAFNKIKSENGNGVQKTNQRVQDLQQKFEA 289 Query: 813 Y-SEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKN---QILLEENQNLQIS 868 Y ++ E L + + +E E+ ++N ++Q+ N Q E Q L Sbjct: 290 YQQQFNKLNSESQENETKLQETKKQLEDLQNELGNKNNQIQELNEQHQKSQTEIQKLNEQ 349 Query: 869 LSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDL 928 ++ QQ L + N + + + QL L ++ + Q + K +E E L Sbjct: 350 ITSNQQRIEELQKNENILVEKDKNINEIKEQLSALNQQIEGF-KDIQNKLDTKTEEFEKL 408 Query: 929 EIEFNTQIESAIRDK-KVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLE 987 E +FN Q +S + +K K +E+ E + + + Q QE + +++LN N++ NK N E Sbjct: 409 EKDFNQQ-KSELEEKIKSKDEEIENLSKKIQDIVEQQQEKQKQLDDLNSNLQNSNKEN-E 466 Query: 988 LIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSM---VS 1044 + + + + + + + + N+L A LKQ E++ QK A + + Sbjct: 467 QLKQEINDFKNKINNSNQDQEQQSNQLKAELKQTQEQLNDSQQKFEQADKELKDLKQQIE 526 Query: 1045 DYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQ----ILVREQDDQ----IKELK 1096 D + KL + + EN++++++ +++L +S+Q E++Q L + D Q K+ K Sbjct: 527 DEKVKLNDKSQESENLKDQLKSANEKLNESQQKLEQIQKNFDDLKQNNDLQKIVDEKQQK 586 Query: 1097 ETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSV 1156 +L E+ KT+ +++ ++ ++ + + LK QE+E+ I S Sbjct: 587 CEELERELKELKTQQEQVTAQVQQLNVEKEEIQTKFNQVEQEKEQLKKQEQEK-IDLLSQ 645 Query: 1157 LQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLST 1216 +++ E+ I LE T++ +Q++ K LE LN E + L + Sbjct: 646 AKQEKENNEQEINNLKQTIANLEKERTDIQIQSQEKDKQLDDAKHTLENLNKEIEQLKNQ 705 Query: 1217 VAELRSSISSAVDQRGFEIAELWKQHLAQREADFQ----KTEHEL---RVQLSAFESKYE 1269 + ++ Q EI ++ K + Q+ + Q K E E+ + QL + Sbjct: 706 NQAI-GDVNEKNKQLESEITQI-KSEIEQKNTEIQSLNSKNETEISEKKQQLEDHTKQVN 763 Query: 1270 QLLDSV-QSSTQEET--NKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSE 1326 QL + + Q ST+ E N+I T + ++ Q KL D + Q++ + Q++ ++ Sbjct: 764 QLNEQIHQLSTENENLKNEIQTNQNIS--QTKLTDLNSEIEGFQKEIEETKLQLDDKNTQ 821 Query: 1327 IEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQE--QSILNINEE--NAQLKKSSX 1382 ++ +V +++ NQ K+ ++ ++I NEE N+ Sbjct: 822 LKGLQVKL----EALEKQLLEKNEEIQKVNQQLKESEQKHEAIQKQNEELQNSLKTLEEK 877 Query: 1383 XXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQ-------KTHEYTITLTQRNDEFE 1435 +V+D + K +L QL+ K EI Q +T ++ Q + Sbjct: 878 DYNQIQNDLNQQVSDLKQKEQDLNKQLDQKLQEINQIKQQLSNETSDFMKKNVQLQQTIQ 937 Query: 1436 NVRQQLVEYEKRIEDL---TYEKESELAILRLKMHENANHYETMQKESEI-ERVKLIEEL 1491 + Q + +Y+++IE + Y+ + E + L+ K++E AN E KE ++ ++V++I EL Sbjct: 938 QLNQTISQYQEQIERIKTDLYQSQQEKSQLQSKLNE-ANR-EIQNKEDDLNKKVEIIAEL 995 Query: 1492 --NVKITESVSLNKQVA--ELNK----ALEEEVAKTNEMQTALENQEIEIVTLNDEITNL 1543 N K + N +V +L+K LE ++ E Q + E +I L +EI L Sbjct: 996 EQNNKDLKINLHNYEVKSYDLDKERFDVLEIQIQHNKEQQVQYKQAEEKIQKLEEEIKKL 1055 Query: 1544 QNMVRASSSKIQKHV 1558 S K+QK + Sbjct: 1056 LADKTDSLEKLQKEI 1070 Score = 134 bits (325), Expect = 1e-29 Identities = 198/970 (20%), Positives = 421/970 (43%), Gaps = 97/970 (10%) Query: 634 QQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLY 693 Q+K E +++ Q ++Q +E + + QI + S K ++ + E+ + E Sbjct: 9 QEKQVEAQNEEQKQEQENNEQKENESEQAQTDPQISSGSNQKFDIEITDEDNDPEIENNQ 68 Query: 694 GTIKDLENDKEDIMNKLQN----YIQ--ENMDLTDKLEKMSAEKISELLAKINHEEQSKI 747 +K + N E++ K N Y Q + + +K K S EK E++ H+ S + Sbjct: 69 TIVKKVGNLAEELKVKFANLETDYDQCKDEKEELEKKYKQSIEKYGEMMKNYEHQIIS-L 127 Query: 748 QTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQ 807 + + I +IQ+ I+ ++ + + + +++ I + ++ K +++ + Q Sbjct: 128 ENENNI--RIQQLQQQIDELKKQNEEKEQSYLNMQQQIKQDKQSFDDIQNKYEEINKHNQ 185 Query: 808 EKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQI 867 E+ K S+ ++ LVN + E+ + + N + K+ I + + LQ Sbjct: 186 EQFKQNSDQWVK---LVN----------LTEEVIFNFYNSNFFTENKDDISSQTHIILQ- 231 Query: 868 SLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIED 927 QQ + L+EK T LAE + + +I E+ + + + ++D Sbjct: 232 ----HQQTFQQLIEKYV-TFLAEQKEKNEAIS----DEAFNKIKSENGNGVQKTNQRVQD 282 Query: 928 LEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLE 987 L+ +F E+ + LN + ++N + + + QL++ +N + N N ++ELN+ + Sbjct: 283 LQQKF----EAYQQQFNKLNSESQENETKLQETKKQLEDLQNELGNKNNQIQELNEQH-- 336 Query: 988 LIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYE 1047 QK QT+ EQ + ++ L QK+E I+ K N +S ++ Sbjct: 337 ------QKSQTEIQKLNEQITSNQQRIEEL--QKNENILVEKDKNINEIKEQLSALNQQI 388 Query: 1048 SKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKEL-KETKLTFEMNI 1106 KL+ EE +++ K D Q EL+ ++ +D++I+ L K+ + E Sbjct: 389 EGFKDIQNKLDTKTEEFEKLEK---DFNQQKSELEEKIKSKDEEIENLSKKIQDIVEQQQ 445 Query: 1107 PKTEGMI-ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLN 1165 K + + ++S ++ + + + +E++ Q ++ L++ +LN Sbjct: 446 EKQKQLDDLNSNLQNSNKENEQLKQEINDFKNKINNSNQDQEQQSNQLKAELKQTQEQLN 505 Query: 1166 TELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSIS 1225 Q+ E + EL D+ ++QI K KL + E++NL + ++ Sbjct: 506 DSQQK-------FEQADKELK--DL--KQQIEDEKVKLNDKSQESENLKDQLKSANEKLN 554 Query: 1226 SAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNK 1285 + Q+ E + L Q D QK E + + E + ++L + T + Sbjct: 555 ES--QQKLEQIQKNFDDLKQNN-DLQKIVDEKQQKCEELERELKELKTQQEQVTAQVQQL 611 Query: 1286 IVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXX 1345 V E++ + N+++ ++E L+ +++ D+++Q + + E E Sbjct: 612 NVEKEEIQTKFNQVEQEKEQLKKQEQEKIDLLSQAKQEKENNEQE----INNLKQTIANL 667 Query: 1346 XXXXXDLRTENQSY-KQMQE--QSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKV 1402 D++ ++Q KQ+ + ++ N+N+E QLK + + E+++ Sbjct: 668 EKERTDIQIQSQEKDKQLDDAKHTLENLNKEIEQLKNQNQAIGDVNE----KNKQLESEI 723 Query: 1403 LELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKES---EL 1459 ++ ++E K++EI + ++++ + E+ +Q+ + ++I L+ E E+ E+ Sbjct: 724 TQIKSEIEQKNTEIQSLNSKNETEISEKKQQLEDHTKQVNQLNEQIHQLSTENENLKNEI 783 Query: 1460 A----ILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKAL--- 1512 I + K+ + + E QKE IE KL +L+ K T+ L ++ L K L Sbjct: 784 QTNQNISQTKLTDLNSEIEGFQKE--IEETKL--QLDDKNTQLKGLQVKLEALEKQLLEK 839 Query: 1513 EEEVAKTNEMQTALENQEIEIVTLNDEITN-LQNMVRASSSKIQKHVSF-ASDTKQGRDE 1570 EE+ K N+ E + I N+E+ N L+ + ++IQ ++ SD KQ + Sbjct: 840 NEEIQKVNQQLKESEQKHEAIQKQNEELQNSLKTLEEKDYNQIQNDLNQQVSDLKQKEQD 899 Query: 1571 QLDNTMNKEL 1580 +NK+L Sbjct: 900 -----LNKQL 904 Score = 127 bits (306), Expect = 3e-27 Identities = 180/928 (19%), Positives = 402/928 (43%), Gaps = 82/928 (8%) Query: 705 DIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYI 764 + N+ Q QEN + + E A+ ++ + N + +I T D +I+ + Sbjct: 14 EAQNEEQKQEQENNEQKEN-ESEQAQTDPQISSGSNQKFDIEI-TDEDNDPEIENNQTIV 71 Query: 765 ENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELV 824 + + + + K + LE +D + LE+K Q E K Y E+ I E Sbjct: 72 KKVGNLAEELKVKFANLETDYDQCKDEKEELEKKYKQSIEKYGEMMKNY-EHQIISLENE 130 Query: 825 NRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKAN 884 N + + + +++Q+ E++ +N+E ++ + ++ + + S D+Q Y + K N Sbjct: 131 NNIRI-----QQLQQQIDELKKQNEEKEQSYLNMQQQIKQDKQSFDDIQNKYEE-INKHN 184 Query: 885 RTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKK 944 + +++ +L +L + I + + + + K+ + ++Q ++ ++ Sbjct: 185 QEQF--KQNSDQWVKLVNLTEEV--IFNFYNSNFFTENKD------DISSQTHIILQHQQ 234 Query: 945 VLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYT 1004 + EK YVT L Q ++ + + ++ N ++ ++ VQ Q + Y Sbjct: 235 TFQQLIEK---YVTFLAEQKEKNEAISDEAFNKIKSENGNGVQKTNQRVQDLQQKFEAYQ 291 Query: 1005 EQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEM 1064 +Q+ NKLN+ ++ + ++ +++ + Q + + + +++ + + + + E+ Sbjct: 292 QQF----NKLNSESQENETKLQETKKQLEDLQ----NELGNKNNQIQELNEQHQKSQTEI 343 Query: 1065 QRVSKQLLDSKQHNEELQ----ILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEP 1120 Q++++Q+ ++Q EELQ ILV E+D I E+KE I + I + ++ Sbjct: 344 QKLNEQITSNQQRIEELQKNENILV-EKDKNINEIKEQLSALNQQIEGFKD--IQNKLDT 400 Query: 1121 MSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLET 1180 +++ ++ K + EE+ + ++ S K+ +++ K QL+ Sbjct: 401 KTEEFEKLEKDFNQQ-------KSELEEKIKSKDEEIENLSKKIQDIVEQQQEKQKQLDD 453 Query: 1181 LNTELTGHDVVNQE---QINQLKSKLEQLNTENDNLLSTV-AELRSSISSAVD-QRGFEI 1235 LN+ L + N++ +IN K+K+ N + + + + AEL+ + D Q+ FE Sbjct: 454 LNSNLQNSNKENEQLKQEINDFKNKINNSNQDQEQQSNQLKAELKQTQEQLNDSQQKFEQ 513 Query: 1236 AELWKQHLAQREADFQ-------KTEHELRVQLSAFESKY---EQLLDSVQSSTQEETNK 1285 A+ + L Q+ D + + L+ QL + K +Q L+ +Q + + Sbjct: 514 ADKELKDLKQQIEDEKVKLNDKSQESENLKDQLKSANEKLNESQQKLEQIQKNFDDLKQN 573 Query: 1286 IVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXX 1345 + V Q K ++ E L+ L+ + V Q++ L E E+ + F Sbjct: 574 NDLQKIVDEKQQKCEELERELKELKTQQEQVTAQVQQLNVEKEEIQTKFNQVEQEKEQLK 633 Query: 1346 XXXXX--DLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVL 1403 DL ++ + K+ EQ I N+ + A L+K +++DA+ + Sbjct: 634 KQEQEKIDLLSQAKQEKENNEQEINNLKQTIANLEKERTDIQIQSQEKDKQLDDAKHTLE 693 Query: 1404 ELTHQLE-LKDS-----EIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKES 1457 L ++E LK+ ++ +K + +TQ E E ++ + E EK+ Sbjct: 694 NLNKEIEQLKNQNQAIGDVNEKNKQLESEITQIKSEIEQKNTEIQSLNSKNETEISEKKQ 753 Query: 1458 ELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVA 1517 +L ++++ + E+E + ++ N+ T+ LN ++ K +EE Sbjct: 754 QLEDHTKQVNQLNEQIHQLSTENENLKNEIQTNQNISQTKLTDLNSEIEGFQKEIEETKL 813 Query: 1518 KTNEMQTALENQEIEIVTL-------NDEITNLQNMVRASSSK---IQK---HVSFASDT 1564 + ++ T L+ ++++ L N+EI + ++ S K IQK + + T Sbjct: 814 QLDDKNTQLKGLQVKLEALEKQLLEKNEEIQKVNQQLKESEQKHEAIQKQNEELQNSLKT 873 Query: 1565 KQGRD-EQLDNTMNKELLDAVPRAELDL 1591 + +D Q+ N +N+++ D + + E DL Sbjct: 874 LEEKDYNQIQNDLNQQVSD-LKQKEQDL 900 Score = 113 bits (271), Expect = 5e-23 Identities = 171/912 (18%), Positives = 395/912 (43%), Gaps = 91/912 (9%) Query: 147 LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNK---------ATTXXX 197 L N + K+N + L + + +T I L E+I Q IE K Sbjct: 318 LQNELGNKNNQIQELNEQHQKSQTEIQKLNEQITSNQQRIEELQKNENILVEKDKNINEI 377 Query: 198 XXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEAN 257 +D + ++ E F +E ++ +K L + I+SKD I +L + Sbjct: 378 KEQLSALNQQIEGFKDIQNKLDTKTEEFEKLEKDFNQQKSELEEKIKSKDEEIENLSKKI 437 Query: 258 KLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLE 317 + + + E + L L+ K I S ++ +E+ S + Sbjct: 438 QDIVEQQQEKQKQLDDLNSNLQNSNKENEQLKQEINDF-KNKINNSNQD----QEQQSNQ 492 Query: 318 IANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRN 377 + EL + E L + Q +KEL++ + E ++ S++ L + N Sbjct: 493 L--KAELKQTQEQLNDSQQKFEQADKELKDLKQQIEDEKVKLNDKSQESENLKDQLKSAN 550 Query: 378 TASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXX 437 K+ SQ E + ++ D N++ K ++ + + E + E T Sbjct: 551 --EKLNE--SQQKLEQIQKNFDDLKQNNDLQK---IVDEKQQKCEELERELKELKTQ--- 600 Query: 438 XXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVN 497 ++ + AQ+Q Q ++E + N++ + +EQLK++ ++I Sbjct: 601 -------QEQVTAQVQ---QLNVEKEEI------QTKFNQVEQEKEQLKKQEQEKI---- 640 Query: 498 VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDS-NKE 556 DL+ + K +E Q + + N+ K +++ +++ ++ K +D+ ++ NKE Sbjct: 641 --DLLSQAKQEKENNEQEINNLKQTIANLEKERTDIQIQSQEKDKQLDDAKHTLENLNKE 698 Query: 557 IVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAI 616 I E+L + +Q + ++ E+ L+ + I+S++ +K E+++L I Sbjct: 699 I----EQLKNQNQAIGDVNEKNKQLESEIT------QIKSEIEQKNTEIQSLNSKNETEI 748 Query: 617 SLLESQKFDLVQELHILQQKYDEVEDKLADI-SQLQSDQVCSEIKSVHLEEQIDALSASK 675 S + Q D ++++ L ++ ++ + ++ +++Q++Q S+ K L +I+ Sbjct: 749 SEKKQQLEDHTKQVNQLNEQIHQLSTENENLKNEIQTNQNISQTKLTDLNSEIEGFQKEI 808 Query: 676 KELALVIENLKLDKEQLYGTIKDLEN---DKEDIMNKLQNYIQENMDLTDKLEKMSAEKI 732 +E L +++ + L ++ LE +K + + K+ ++E+ + ++K + E++ Sbjct: 809 EETKLQLDDKNTQLKGLQVKLEALEKQLLEKNEEIQKVNQQLKESEQKHEAIQKQN-EEL 867 Query: 733 SELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRR 792 L + ++ ++IQ ++ ++ + +++ +L + I ++++ ++ + Sbjct: 868 QNSLKTLEEKDYNQIQND--LNQQVSDLKQKEQDLNKQLDQKLQEINQIKQQLS---NET 922 Query: 793 YSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHE--NKE 850 +K QL +Q+ + S+Y Q + + L ++ +L E E NKE Sbjct: 923 SDFMKKNVQLQQTIQQLNQTISQYQEQIERIKTDLYQSQQEKSQLQSKLNEANREIQNKE 982 Query: 851 --LQKKNQILLE---ENQNLQISLSDMQ-QHYNALVEKANRTDLAESESTKYQTQLRDLE 904 L KK +I+ E N++L+I+L + + + Y+ E+ + ++ + + Q Q + E Sbjct: 983 DDLNKKVEIIAELEQNNKDLKINLHNYEVKSYDLDKERFDVLEIQIQHNKEQQVQYKQAE 1042 Query: 905 SNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQL 964 ++++ E + L+ K +E L+ E T E I ++ +++K+ N+ E Q+ Sbjct: 1043 EKIQKLEEEIKKLLADKTDSLEKLQKEIKT--EQVIGEE--MSKKFRSNL-----AELQI 1093 Query: 965 QEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEE 1024 +N++EN + +L ++ L + K T+ + + + + NA + Sbjct: 1094 NNEQNSLENSQKTINQLAEVVLRKV-KDCFYSSTKIVQISRLFYDGSDGRNA----SQDN 1148 Query: 1025 IIALNQKINNAQ 1036 ++L Q++N AQ Sbjct: 1149 ALSLIQELNEAQ 1160 >UniRef50_A2FX23 Cluster: Formin Homology 2 Domain containing protein; n=1; Trichomonas vaginalis G3|Rep: Formin Homology 2 Domain containing protein - Trichomonas vaginalis G3 Length = 2354 Score = 172 bits (419), Expect = 6e-41 Identities = 305/1464 (20%), Positives = 639/1464 (43%), Gaps = 159/1464 (10%) Query: 215 KQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKL 274 KQ K+Q+ I + + + EK+ + K+ E R+ + E + +AA + ++ Sbjct: 494 KQSYKKLQDQ-IEEKTKIEGEKEEMKKENEDLKARLKTAESTIVIQKAA----AESYTSR 548 Query: 275 AQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKI-ELLEH 333 +L+Q ++ I+ EK + +K + E ++KI E L+ Sbjct: 549 VNDLQQKLAEYESKLQQQISANEEKIKNQENEKVTLSQK----LKEQEEESRKIIESLQS 604 Query: 334 LNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSET 393 + +++ N E++ L + K+ + S + + +KS N + + S +L ++ Sbjct: 605 QSKDLQKMNNEMQVNLQNEISILKSKLTESNQKYETLEQKSS-NESDRTASALQELKTQN 663 Query: 394 LNQDTDKK---INKNEIAKLEMV----IQSLNKDLVD-----KEYVISEKDTXXXXXXXX 441 N ++D + NEI K + I+ LN D+ KE + +++ Sbjct: 664 KNLESDIENLTSKLNEITKQNEMKSREIERLNADIEQEKSKYKEQIDQKQNQIDQQFAML 723 Query: 442 XXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLK---QELNDEIKDVNV 498 K + Q Q+ + +++ L+ T + + ++++K E+L+ +EL +E K V Sbjct: 724 NDLKQQIDQQKQMNEELNIKSQRLVE--TKSSEYSDLSKQLEELQIRNKEL-EESKKVLH 780 Query: 499 KDLIEKLKSAEEQITQLNDEIDAANKNM---IKVKSNHKLKLKQMQKTIDN-FSKVSDS- 553 DL++K +S +++ Q ++I KN+ ++ N K +L++ K+ + F+++ + Sbjct: 781 SDLLQKQQSIKQEKEQEIEQITNQLKNVNISLENSLNEKSQLEEQLKSKETKFNELKEKL 840 Query: 554 NKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRL 613 N I L EE L +++ +L+ + + L+ + ES+ ++ I +N T+L Sbjct: 841 NTSIENLREENETLKEEINKLQTTTADEKTTLLQSFNA---ESEPLRQKINQQNQIITKL 897 Query: 614 KAISLLESQKFDLVQELHIL---------QQKYDEVEDKLADISQLQSDQVCSEIKSV-- 662 + + K + +L + Q++++ + KL D Q Q Q+ +E KSV Sbjct: 898 QRENQQLQNKMEEQTQLLLTEFNNQRQNDQKEHEIIVKKLNDELQ-QKQQIYNEEKSVLE 956 Query: 663 --HLEEQIDALSASKKELALVIENLKLDKEQLY----GTIKDL----ENDKEDIMNK--- 709 +E+ + L SK+++ +I + +K+QL IK + EN+K+ I+N Sbjct: 957 STFSQEKQNMLLQSKQQINQIILQNQSEKDQLTTNYENKIKSIMEQNENEKQIIINNHNI 1016 Query: 710 -LQ----NYIQENMDLTDKL--EKMSAEK-ISELLAKINHEEQS------KIQT-QFGID 754 LQ NY E L K +K + E+ I EL K++ +E + ++QT Q ++ Sbjct: 1017 ALQTTYNNYQSEKDQLVKKFNDDKNNYEQTIKELKQKVDRQENNNKNQAYELQTAQKELE 1076 Query: 755 AKIQERDLYI-------ENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQ 807 +I + + + E + ++KYK + +E + E+ L + + + +Q Sbjct: 1077 KQINKYNQVVDEANNRQEKLIGHINKYKDAVKERDEELQNRENIIDQLNNEIKKRDNLIQ 1136 Query: 808 EKQKAYSE----YTIQEDELVNRLAVLMD--HDRVVEKQLLEIE-----HENKEL-QKKN 855 ++K Y + Y +EL ++ L D + EK+ ++++ EN++L +KK Sbjct: 1137 TREKEYKQNLKAYEKTNNELNVKVQTLNDNLYQEKQEKEQIKVQMAKNNEENQKLFEKKE 1196 Query: 856 QILLEENQNLQISLSDMQQHYNALV--EKANRTDLAE--SESTKYQTQLRDLESNLKRIT 911 Q L ++ +L + +DM + + EK N +L E ++ +K L+ +++NL ++ Sbjct: 1197 QELNKKINDLMVQGTDMNEQIIKQLNSEKENSHNLQEIINKQSKELDDLKVVQNNLVSVS 1256 Query: 912 HEHQTLIVQKKK---EIEDLEIEFNTQ------IESAIRDKKV----LNEKYEKNIEYVT 958 E++ L K+ ++ LE + + +E + + K+ L+EKY+K ++ Sbjct: 1257 KENEGLKSDKENLTTQVNSLEQKLTNEEEKVKELEESQKQKEKEYQRLSEKYDKLKDHAI 1316 Query: 959 QLEAQLQEYKNNIENLNMNV-EELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNAL 1017 L QL+ +NN N + E++N +N E I K + Q+ EQ ++ I++ + Sbjct: 1317 NLREQLENIENNSNESNNKLNEKINLLNEE-ISKLSNENSQQNNLIQEQKVS-ISQTTSQ 1374 Query: 1018 LKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQH 1077 LK E A N+ +NN Y + + KL ++ E++ ++ L +SKQ+ Sbjct: 1375 LK----EFEAKNEDLNNKCNKYEEENNTLKQKLTSEVNNSNSLSEKLSELTSLLDNSKQN 1430 Query: 1078 NEELQI----LVREQDDQIKELKETKLTFE----------MNIPKTEGMIISSTIEPMSD 1123 ++ Q LV + QIK+L E KL E +N + IS+ + Sbjct: 1431 HQNAQSKYDELVNSSNSQIKDLTE-KLNEEKAKNDSANNKLNDLTKQNEEISAKLSHSES 1489 Query: 1124 DANNVDXXXXXXXXXXXXLKV--QEEEEFIQER----SVLQEQSAKLNTELQECYTKIIQ 1177 + ++V L+ Q E +QE+ S ++E AK E E +++++ Sbjct: 1490 ELSSVKEENNKLQSEVTTLRTTNQNNENKLQEKEKELSDVKESMAKREKEQSEVISQLMK 1549 Query: 1178 LETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAE 1237 +++L + + +Q+ + ++ +++ ++ + + L+ +++ QR E Sbjct: 1550 SADADSKLN-QAIEDLQQMQKSNAEKDKIISDQQKKIEVIVPLQLQMTNL--QREKEELN 1606 Query: 1238 LWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQE--ETNKIV-TMEQVTS 1294 ++ + K +E+ +LS + QL D V T E N +V QV + Sbjct: 1607 ANLENTKNELKEKTKELNEVNEKLSKRSKEIVQLRDEVNQKTVEISSLNDLVHNQNQVNA 1666 Query: 1295 -LQN---KLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXX 1350 L+N KLQ+KEE L Q+K ++ + E + + + Sbjct: 1667 KLENTKAKLQEKEELLEISQKKLREISSSNETFKENLNALQTE-NEQLKKENSENSENIR 1725 Query: 1351 DLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLE 1410 L + + + E +L + N L+ + V + E ++ L + + Sbjct: 1726 KLNEQISTINRQNEDKLLELKHNNDALQNTIQNVTSKNSQLEADVQNKEKELQRLNNLVT 1785 Query: 1411 LKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENA 1470 E+ K ++ Q+N + Q++ + ++ I L E + K+ E+ Sbjct: 1786 EISGELKSKENKAEDQKQQQNSILSSKEQEIKQLKEEINQLNSNSEKLVQNYNSKLEES- 1844 Query: 1471 NHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQE 1530 E + ++ + + LN K+ + S NK++++ +LEE+ KTN + E + Sbjct: 1845 ---EKKINKLNLKHGEEVTSLNTKLQQISSENKKISQEKTSLEED--KTN-LSKENEEYK 1898 Query: 1531 IEIVTLNDEITNLQNMVRASSSKI 1554 ++ L ++ L N + +I Sbjct: 1899 SQLQDLKKKLEELNNTISDKEKEI 1922 Score = 169 bits (410), Expect = 7e-40 Identities = 245/1190 (20%), Positives = 528/1190 (44%), Gaps = 116/1190 (9%) Query: 454 LEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQIT 513 +E Q+ E + TN E V+E+L++++ K+ ++ + + K ++QI Sbjct: 448 IESQKPSESDDDGKILTNKEAKKMFEDVREKLEEQIRT--KEDELRAIKQSYKKLQDQIE 505 Query: 514 QLNDEIDAANKNMIKVKSNHKLKLKQMQKTI-------DNF-SKVSDSNKEIV----RLT 561 + +I+ + M K + K +LK + TI +++ S+V+D +++ +L Sbjct: 506 E-KTKIEGEKEEMKKENEDLKARLKTAESTIVIQKAAAESYTSRVNDLQQKLAEYESKLQ 564 Query: 562 EELHHLSQKVAELEEEKGNLQLHLVDYD--SGRMIES--DVYKKMIEMENLAETRLK-AI 616 +++ +K+ E EK L L + + S ++IES K + +M N + L+ I Sbjct: 565 QQISANEEKIKNQENEKVTLSQKLKEQEEESRKIIESLQSQSKDLQKMNNEMQVNLQNEI 624 Query: 617 SLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKK 676 S+L+S+ + Q+ L+QK D+ A S LQ + ++ +LE I+ L++ Sbjct: 625 SILKSKLTESNQKYETLEQKSSNESDRTA--SALQE----LKTQNKNLESDIENLTSKLN 678 Query: 677 ELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELL 736 E+ E + E+L I+ ++ ++ +++ QN I + + + L K ++ ++ Sbjct: 679 EITKQNEMKSREIERLNADIEQEKSKYKEQIDQKQNQIDQQFAMLNDL-KQQIDQQKQMN 737 Query: 737 AKINHEEQSKIQTQFG--IDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYS 794 ++N + Q ++T+ D Q +L I N E E SK L++ ++ +++ Sbjct: 738 EELNIKSQRLVETKSSEYSDLSKQLEELQIRNKELEESKKVLHSDLLQKQQSIKQEKEQE 797 Query: 795 LERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKK 854 +E+ +QL + + + +E + E++L ++ + + EK IE+ L+++ Sbjct: 798 IEQITNQLKNVNISLENSLNEKSQLEEQLKSKETKF---NELKEKLNTSIEN----LREE 850 Query: 855 NQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEH 914 N+ L EE LQ + +D EK +ES + ++ + ++ E+ Sbjct: 851 NETLKEEINKLQTTTAD---------EKTTLLQSFNAESEPLRQKINQQNQIITKLQREN 901 Query: 915 QTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIEN- 973 Q L + +++ + L EFN Q ++ ++ +++ +K ++ Q+ E K+ +E+ Sbjct: 902 QQLQNKMEEQTQLLLTEFNNQRQNDQKEHEIIVKKLNDELQQKQQI---YNEEKSVLEST 958 Query: 974 LNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKIN 1033 + + + + + I++ + + Q++ T Y N+I + + + ++E+ I +N Sbjct: 959 FSQEKQNMLLQSKQQINQIILQNQSEKDQLTTNYENKIKSI--MEQNENEKQIIINNHNI 1016 Query: 1034 NAQVSYMSMVSDYESKLAQFTTKLENMEEEM----QRVSKQLLDSKQHNEELQILVREQD 1089 Q +Y + S+ + + +F N E+ + Q+V +Q ++K ELQ +E + Sbjct: 1017 ALQTTYNNYQSEKDQLVKKFNDDKNNYEQTIKELKQKVDRQENNNKNQAYELQTAQKELE 1076 Query: 1090 DQIKELKETKLTFEMNIPKTEGMI------ISSTIEPMSDDANNVDXXXXXXXXXXXXLK 1143 QI + + K G I + E + + N +D ++ Sbjct: 1077 KQINKYNQVVDEANNRQEKLIGHINKYKDAVKERDEELQNRENIIDQLNNEIKKRDNLIQ 1136 Query: 1144 VQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKL 1203 +E+E + Q ++ + +LN ++Q + Q + ++ N E+ +L K Sbjct: 1137 TREKE-YKQNLKAYEKTNNELNVKVQTLNDNLYQEKQEKEQIKVQMAKNNEENQKLFEKK 1195 Query: 1204 EQ-LNTENDNLLSTVAELRSSISSAVD---QRGFEIAELWKQHLAQREADFQKTEHELRV 1259 EQ LN + ++L+ ++ I ++ + + E+ + +E D K V Sbjct: 1196 EQELNKKINDLMVQGTDMNEQIIKQLNSEKENSHNLQEIINKQ--SKELDDLKVVQNNLV 1253 Query: 1260 QLS----AFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYAD 1315 +S +S E L V S Q+ TN+ E+V L+ + KE+ + L EKY Sbjct: 1254 SVSKENEGLKSDKENLTTQVNSLEQKLTNE---EEKVKELEESQKQKEKEYQRLSEKYDK 1310 Query: 1316 VINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENA 1375 + + LR ++E+ + N+S ++ E+ L +NEE + Sbjct: 1311 LKDHAINLREQLENIE---------------------NNSNESNNKLNEKINL-LNEEIS 1348 Query: 1376 QLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFE 1435 +L + ++ +++ E E K+ ++ K ++Y +E Sbjct: 1349 KLSNENSQQNNLIQEQKVSISQTTSQLKEF----EAKNEDLNNKCNKY-------EEENN 1397 Query: 1436 NVRQQLVEYEKRIEDLTYEKESELAIL---RLKMHENA-NHYETMQKESEIERVKLIEEL 1491 ++Q+L L+ EK SEL L + H+NA + Y+ + S + L E+L Sbjct: 1398 TLKQKLTSEVNNSNSLS-EKLSELTSLLDNSKQNHQNAQSKYDELVNSSNSQIKDLTEKL 1456 Query: 1492 NVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASS 1551 N + ++ S N ++ +L K EE AK + ++ L + + E L E+T L+ + + Sbjct: 1457 NEEKAKNDSANNKLNDLTKQNEEISAKLSHSESELSSVKEENNKLQSEVTTLRTTNQNNE 1516 Query: 1552 SKIQKHVSFASDTKQG---RDEQLDNTMNKELLDAVPRAELDLAMYMLHQ 1598 +K+Q+ SD K+ R+++ +++ + A ++L+ A+ L Q Sbjct: 1517 NKLQEKEKELSDVKESMAKREKEQSEVISQLMKSADADSKLNQAIEDLQQ 1566 Score = 156 bits (378), Expect = 5e-36 Identities = 280/1424 (19%), Positives = 602/1424 (42%), Gaps = 129/1424 (9%) Query: 230 AEWKDEKQRLLKDIESKDV-RISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXX 288 A++ D K ES D +I + +EA K+ E R + LE +E E Sbjct: 441 AKYLDSSIESQKPSESDDDGKILTNKEAKKMFEDVREK--LEEQIRTKEDELRAIKQSYK 498 Query: 289 XXXXXXLAKQSIEPSCEE-KTEIEE-KGSLEIANMTELTKKIELLEHLNC--QIRQTNKE 344 K IE EE K E E+ K L+ A T + +K + + ++Q E Sbjct: 499 KLQDQIEEKTKIEGEKEEMKKENEDLKARLKTAESTIVIQKAAAESYTSRVNDLQQKLAE 558 Query: 345 LENKLATM--GTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKI 402 E+KL E K + ++K + K + K+ S + + + ++ Sbjct: 559 YESKLQQQISANEEKIKNQENEKVTLSQKLKEQEEESRKIIESLQSQSKDLQKMNNEMQV 618 Query: 403 N-KNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHME 461 N +NEI+ L+ + N+ K + +K + + +L+ +++ ++E Sbjct: 619 NLQNEISILKSKLTESNQ----KYETLEQKSSNESDRTASA------LQELKTQNK-NLE 667 Query: 462 GPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDA 521 + T +NEI K Q ++K EI+ +N D+ ++ +EQI Q ++ID Sbjct: 668 SD----IENLTSKLNEITK-QNEMKSR---EIERLNA-DIEQEKSKYKEQIDQKQNQIDQ 718 Query: 522 --ANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKG 579 A N +K + + + ++ + + I + V + E L+++L L + ELEE K Sbjct: 719 QFAMLNDLKQQIDQQKQMNE-ELNIKSQRLVETKSSEYSDLSKQLEELQIRNKELEESKK 777 Query: 580 NLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDE 639 L L+ I+ + +++ ++ N + ++ ++K L ++L + K++E Sbjct: 778 VLHSDLLQKQQS--IKQEKEQEIEQITNQLKNVNISLENSLNEKSQLEEQLKSKETKFNE 835 Query: 640 VEDKL-ADISQLQSD-----QVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLY 693 +++KL I L+ + + +++++ +E+ L + E E L+ Q Sbjct: 836 LKEKLNTSIENLREENETLKEEINKLQTTTADEKTTLLQSFNAES----EPLRQKINQQN 891 Query: 694 GTIKDLENDKEDIMNKLQNYIQ------ENMDLTDKLE-KMSAEKISELLAK---INHEE 743 I L+ + + + NK++ Q N D+ E ++ +K+++ L + I +EE Sbjct: 892 QIITKLQRENQQLQNKMEEQTQLLLTEFNNQRQNDQKEHEIIVKKLNDELQQKQQIYNEE 951 Query: 744 QSKIQTQFGIDAK---IQERDLYIENIESELSKYKSRICRLEESI-AVMEDRRYSLERKA 799 +S +++ F + + +Q + + I S+ E I ++ME K Sbjct: 952 KSVLESTFSQEKQNMLLQSKQQINQIILQNQSEKDQLTTNYENKIKSIMEQNE---NEKQ 1008 Query: 800 DQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILL 859 + ++ Q Y+ Y ++D+LV + D E+ + E++ + + N+ Sbjct: 1009 IIINNHNIALQTTYNNYQSEKDQLVKKFN---DDKNNYEQTIKELKQKVDRQENNNKNQA 1065 Query: 860 EENQNLQISLSDMQQHYNALVEKAN-RTDLAESESTKYQTQLRDLESNLKR---ITHEHQ 915 E Q Q L YN +V++AN R + KY+ +++ + L+ I + Sbjct: 1066 YELQTAQKELEKQINKYNQVVDEANNRQEKLIGHINKYKDAVKERDEELQNRENIIDQLN 1125 Query: 916 TLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLN 975 I ++ I+ E E+ +++ + LN K + + + Q + + ++ K + N Sbjct: 1126 NEIKKRDNLIQTREKEYKQNLKAYEKTNNELNVKVQTLNDNLYQEKQEKEQIKVQMAKNN 1185 Query: 976 MNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNA 1035 ++L + + ++K + Q D EQ I ++N K+ + Q+I N Sbjct: 1186 EENQKLFEKKEQELNKKINDLMVQGTDMNEQIIKQLNSE----KENSHNL----QEIINK 1237 Query: 1036 QVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQL--LDSKQHNEELQILVREQDDQIK 1093 Q + + ++ L + + E ++ + + ++ Q+ L+ K NEE ++ E+ + K Sbjct: 1238 QSKELDDLKVVQNNLVSVSKENEGLKSDKENLTTQVNSLEQKLTNEEEKVKELEESQKQK 1297 Query: 1094 ELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQE 1153 E + +L+ + + K + + +E + +++N + + E Q+ Sbjct: 1298 EKEYQRLSEKYDKLKDHAINLREQLENIENNSNESNNKLNEKINLLNEEISKLSNENSQQ 1357 Query: 1154 RSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQ----------EQINQLKSKL 1203 +++QEQ ++ + + E LN + ++ N N L KL Sbjct: 1358 NNLIQEQKVSISQTTSQLKEFEAKNEDLNNKCNKYEEENNTLKQKLTSEVNNSNSLSEKL 1417 Query: 1204 EQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSA 1263 +L + DN +S V+ +I +L ++ L + +A ++L Sbjct: 1418 SELTSLLDNSKQNHQNAQSKYDELVNSSNSQIKDLTEK-LNEEKAKNDSANNKLNDLTKQ 1476 Query: 1264 FESKYEQLL--DSVQSSTQEETNKI---VTMEQVTSL--QNKLQDKEEHLRNLQEKYA-- 1314 E +L +S SS +EE NK+ VT + T+ +NKLQ+KE+ L +++E A Sbjct: 1477 NEEISAKLSHSESELSSVKEENNKLQSEVTTLRTTNQNNENKLQEKEKELSDVKESMAKR 1536 Query: 1315 -----DVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQM---QEQS 1366 +VI+Q+ ++S D K+ + ++ Q ++ + Sbjct: 1537 EKEQSEVISQL--MKSADADSKLNQAIEDLQQMQKSNAEKDKIISDQQKKIEVIVPLQLQ 1594 Query: 1367 ILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTI- 1425 + N+ E +L + +N+ K+ + + ++ E+ QKT E + Sbjct: 1595 MTNLQREKEELNANLENTKNELKEKTKELNEVNEKLSKRSKEIVQLRDEVNQKTVEISSL 1654 Query: 1426 -----TLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKES 1480 Q N + EN + +L E E+ +E ++ +K E++ EN N +T ++ Sbjct: 1655 NDLVHNQNQVNAKLENTKAKLQEKEELLE-ISQKKLREISSSNETFKENLNALQTENEQL 1713 Query: 1481 EIERVKLIEELNVKITESVS-LNKQ----VAEL---NKALEEEV----AKTNEMQTALEN 1528 + E + E + K+ E +S +N+Q + EL N AL+ + +K ++++ ++N Sbjct: 1714 KKENSENSENIR-KLNEQISTINRQNEDKLLELKHNNDALQNTIQNVTSKNSQLEADVQN 1772 Query: 1529 QEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQL 1572 +E E+ LN+ +T + +++ +K + + +++++ Sbjct: 1773 KEKELQRLNNLVTEISGELKSKENKAEDQKQQQNSILSSKEQEI 1816 Score = 149 bits (360), Expect = 8e-34 Identities = 265/1412 (18%), Positives = 572/1412 (40%), Gaps = 118/1412 (8%) Query: 101 KEILMEKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKE--KDNAL 158 K L E ++Y+ L ++SS R + D+ +L++ + E K N Sbjct: 628 KSKLTESNQKYETLEQKSSNESDRTASALQELKTQNKNLE-SDIENLTSKLNEITKQN-- 684 Query: 159 SVLQVKMKIMETTILDL-QEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQ 217 ++K + +E D+ QEK K+QI + +N+ + + Sbjct: 685 ---EMKSREIERLNADIEQEKSKYKEQIDQKQNQIDQQFAMLNDLKQQIDQQKQMNEELN 741 Query: 218 MTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQE 277 + K Q +E+ D L K +E +R LEE+ K+L + ++ + + QE Sbjct: 742 I-KSQRLVETKSSEYSD----LSKQLEELQIRNKELEESKKVLHS---DLLQKQQSIKQE 793 Query: 278 LEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIEL-LEHLNC 336 EQ S+E S EK+++EE+ + EL +K+ +E+L Sbjct: 794 KEQEIEQITNQLKNVNI----SLENSLNEKSQLEEQLKSKETKFNELKEKLNTSIENLR- 848 Query: 337 QIRQTNKELENKLATMGTESKA--VSSPSKKGSPLISRKSGRNTA-SKMKSPWSQLSSET 393 + +T KE NKL T + K + S + + PL + + +N +K++ QL ++ Sbjct: 849 EENETLKEEINKLQTTTADEKTTLLQSFNAESEPLRQKINQQNQIITKLQRENQQLQNKM 908 Query: 394 LNQD----TD-KKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTL 448 Q T+ +N+ + E++++ LN +L K+ + +E+ + L Sbjct: 909 EEQTQLLLTEFNNQRQNDQKEHEIIVKKLNDELQQKQQIYNEEKSVLESTFSQEKQNMLL 968 Query: 449 IAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSA 508 ++ Q+ + TN E N+I + EQ + E I + N+ + Sbjct: 969 QSKQQINQIILQNQSEKDQLTTNYE--NKIKSIMEQNENEKQIIINNHNI--------AL 1018 Query: 509 EEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNK-EIVRLTEELHHL 567 + E D K K+N++ +K++++ +D + + E+ +EL Sbjct: 1019 QTTYNNYQSEKDQLVKKFNDDKNNYEQTIKELKQKVDRQENNNKNQAYELQTAQKELEKQ 1078 Query: 568 SQKVAELEEEKGNLQLHLVDY-----DSGRMIESDVYKKMIEMENLAETRLKAISLLESQ 622 K ++ +E N Q L+ + D+ + + ++ + ++ L K +L++++ Sbjct: 1079 INKYNQVVDEANNRQEKLIGHINKYKDAVKERDEELQNRENIIDQLNNEIKKRDNLIQTR 1138 Query: 623 KFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVI 682 + + Q L ++ +E+ K+ Q +D + E + +EQI A E Sbjct: 1139 EKEYKQNLKAYEKTNNELNVKV----QTLNDNLYQEKQE---KEQIKVQMAKNNE----- 1186 Query: 683 ENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKM--SAEKISELLAKIN 740 EN KL E ++++ K+ + + + D+ +++ K S ++ S L +I Sbjct: 1187 ENQKL-----------FEKKEQELNKKINDLMVQGTDMNEQIIKQLNSEKENSHNLQEII 1235 Query: 741 HEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKAD 800 +++ ++ D K+ + +L ++ E KS L + +E + + E K Sbjct: 1236 NKQSKELD-----DLKVVQNNLV--SVSKENEGLKSDKENLTTQVNSLEQKLTNEEEKVK 1288 Query: 801 QLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKK-NQILL 859 +L ++K+K Y + + D+L DH + +QL IE+ + E K N+ + Sbjct: 1289 ELEESQKQKEKEYQRLSEKYDKL-------KDHAINLREQLENIENNSNESNNKLNEKIN 1341 Query: 860 EENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIV 919 N+ + ++ Q N + E+ S+ +++ + DL + + E+ TL Sbjct: 1342 LLNEEISKLSNENSQQNNLIQEQKVSISQTTSQLKEFEAKNEDLNNKCNKYEEENNTLKQ 1401 Query: 920 QKKKEIEDLEI--EFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMN 977 + E+ + E +++ S + + K ++ + +Y + + + K+ E LN Sbjct: 1402 KLTSEVNNSNSLSEKLSELTSLLDNSKQNHQNAQS--KYDELVNSSNSQIKDLTEKLNEE 1459 Query: 978 VEELNKMNLELIDKHVQKQQTQSP-DYTEQYINEINKLNALLKQKDEEIIALNQKINNAQ 1036 + + N +L D Q ++ + ++E ++ + + N L+ + + NQ N Sbjct: 1460 KAKNDSANNKLNDLTKQNEEISAKLSHSESELSSVKEENNKLQSEVTTLRTTNQNNENK- 1518 Query: 1037 VSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELK 1096 + + E +L+ + E+E V QL+ S + +L + + K Sbjct: 1519 ------LQEKEKELSDVKESMAKREKEQSEVISQLMKSADADSKLNQAIEDLQQMQKSNA 1572 Query: 1097 ETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSV 1156 E K E I P+ N+ K E +E +E + Sbjct: 1573 EKDKIISDQQKKIE------VIVPLQLQMTNLQREKEELNANLENTK-NELKEKTKELNE 1625 Query: 1157 LQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQIN-QLKSKLEQLNTENDNLLS 1215 + E+ +K + E+ + ++ Q +T+ V NQ Q+N +L++ +L + + L Sbjct: 1626 VNEKLSKRSKEIVQLRDEVNQ-KTVEISSLNDLVHNQNQVNAKLENTKAKLQEKEELLEI 1684 Query: 1216 TVAELRS-SISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDS 1274 + +LR S S+ + + + L + ++ + +L Q+S + E L Sbjct: 1685 SQKKLREISSSNETFKENLNALQTENEQLKKENSENSENIRKLNEQISTINRQNEDKLLE 1744 Query: 1275 VQSSTQEETNKIVTMEQVTS-LQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVA 1333 ++ + N I + S L+ +Q+KE+ L+ L ++ +++ ++ ED+K Sbjct: 1745 LKHNNDALQNTIQNVTSKNSQLEADVQNKEKELQRLNNLVTEISGELKSKENKAEDQK-- 1802 Query: 1334 FXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXX 1393 +++ + Q+ S + N++L++S Sbjct: 1803 -----QQQNSILSSKEQEIKQLKEEINQLNSNSEKLVQNYNSKLEESEKKINKLNLKHGE 1857 Query: 1394 RVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTY 1453 V K+ +++ + + K S+ E L++ N+E+++ Q L + + + + Sbjct: 1858 EVTSLNTKLQQISSENK-KISQEKTSLEEDKTNLSKENEEYKSQLQDLKKKLEELNNTIS 1916 Query: 1454 EKESELAILRLKMHENANHYETMQKESEIERV 1485 +KE E+ L+L + E T + E E V Sbjct: 1917 DKEKEINDLKLHVVETTEEKGTQEVAEEEEEV 1948 Score = 124 bits (300), Expect = 2e-26 Identities = 167/876 (19%), Positives = 382/876 (43%), Gaps = 61/876 (6%) Query: 309 EIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSP 368 EI+++ +L E + ++ E N ++ + L + L E + + K + Sbjct: 1127 EIKKRDNLIQTREKEYKQNLKAYEKTNNELNVKVQTLNDNLYQEKQEKEQIKVQMAKNNE 1186 Query: 369 LISRKSGRNTASKMKSPWSQLSSE--TLNQDTDKKIN--KNEIAKLEMVIQSLNKDLVDK 424 ++K ++ + L + +N+ K++N K L+ +I +K+L D Sbjct: 1187 E-NQKLFEKKEQELNKKINDLMVQGTDMNEQIIKQLNSEKENSHNLQEIINKQSKELDDL 1245 Query: 425 EYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQ 484 + V + + K+ L Q+ Q+ L + +++ E K +E+ Sbjct: 1246 KVVQNNLVSVSKENEGLKSDKENLTTQVNSLEQK------LTNEEEKVKELEESQKQKEK 1299 Query: 485 LKQELN---DEIKD--VNVKDLIEKLKS-AEEQITQLNDEIDAANKNMIKVKSNHKLKLK 538 Q L+ D++KD +N+++ +E +++ + E +LN++I+ N+ + K+ + + + Sbjct: 1300 EYQRLSEKYDKLKDHAINLREQLENIENNSNESNNKLNEKINLLNEEISKLSNENSQQNN 1359 Query: 539 QMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDV 598 +Q+ + S+ + KE E+L++ K + EEE L+ L + + + Sbjct: 1360 LIQEQKVSISQTTSQLKEFEAKNEDLNN---KCNKYEEENNTLKQKLTSEVNN---SNSL 1413 Query: 599 YKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSE 658 +K+ E+ +L + + +S K+D ++ +++D +++ ++ + Sbjct: 1414 SEKLSELTSLLDNSKQNHQNAQS-KYD-----ELVNSSNSQIKDLTEKLNEEKAKNDSAN 1467 Query: 659 IKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENM 718 K L +Q + +SA + ++K + +L + L ++ NKLQ +E Sbjct: 1468 NKLNDLTKQNEEISAKLSHSESELSSVKEENNKLQSEVTTLRTTNQNNENKLQEKEKELS 1527 Query: 719 DLTDKLEKMSAEKISELLAKI--NHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKS 776 D+ + + K E+ SE+++++ + + SK+ ++Q+ + + I S+ K Sbjct: 1528 DVKESMAKREKEQ-SEVISQLMKSADADSKLNQAIEDLQQMQKSNAEKDKIISDQQKKIE 1586 Query: 777 RICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRV 836 I L+ + ++ + L + + L+EK K +E + + + L D Sbjct: 1587 VIVPLQLQMTNLQREKEELNANLENTKNELKEKTKELNEVNEKLSKRSKEIVQLRDE--- 1643 Query: 837 VEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKY 896 V ++ +EI N + +NQ+ N L+ + + +Q+ L + S + + Sbjct: 1644 VNQKTVEISSLNDLVHNQNQV----NAKLENTKAKLQEKEELLEISQKKLREISSSNETF 1699 Query: 897 QTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEY 956 + L L++ +++ E+ +K E + N Q E + + K N+ + I+ Sbjct: 1700 KENLNALQTENEQLKKENSENSENIRKLNEQIST-INRQNEDKLLELKHNNDALQNTIQN 1758 Query: 957 VTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNA 1016 VT +QL+ +++N ++ LN + E I ++ ++ ++ D +Q N+ Sbjct: 1759 VTSKNSQLEA---DVQNKEKELQRLNNLVTE-ISGELKSKENKAEDQKQQQ-------NS 1807 Query: 1017 LLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENME----EEMQRVSKQL- 1071 +L K++EI L ++IN + +V +Y SKL + K+ + EE+ ++ +L Sbjct: 1808 ILSSKEQEIKQLKEEINQLNSNSEKLVQNYNSKLEESEKKINKLNLKHGEEVTSLNTKLQ 1867 Query: 1072 ---LDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNV 1128 ++K+ ++E L ++ + KE +E K + K E +++TI + N++ Sbjct: 1868 QISSENKKISQEKTSLEEDKTNLSKENEEYKSQLQDLKKKLEE--LNNTISDKEKEINDL 1925 Query: 1129 DXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKL 1164 +V EEEE + E + L+ S L Sbjct: 1926 KLHVVETTEEKGTQEVAEEEEEVGEMAPLKPVSNNL 1961 Score = 81.0 bits (191), Expect = 2e-13 Identities = 125/584 (21%), Positives = 230/584 (39%), Gaps = 49/584 (8%) Query: 90 ISESLANTLKQKEILMEKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSN 149 + + L + + L EK+ + L S + Q+ D+T N Sbjct: 1399 LKQKLTSEVNNSNSLSEKLSELTSLLDNSKQNH-QNAQSKYDELVNSSNSQIKDLTEKLN 1457 Query: 150 TIKEK-DNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXX 208 K K D+A + L K E L +E + E NK + Sbjct: 1458 EEKAKNDSANNKLNDLTKQNEEISAKLSHSESELSSVKEENNKLQSEVTTLRTTNQNNEN 1517 Query: 209 XXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLK--DIESK-DVRISSLEEANKLLEAARF 265 E K+ ++ ++E+ E E + +L+K D +SK + I L++ K A + Sbjct: 1518 KLQEKEKE-LSDVKESMAKREKEQSEVISQLMKSADADSKLNQAIEDLQQMQKS-NAEKD 1575 Query: 266 EISLEHSKLAQELEQXXXXXXXXXXXXXXL------AKQSIEPSCEEKTEIEEK---GSL 316 +I + K + + L K ++ +E E+ EK S Sbjct: 1576 KIISDQQKKIEVIVPLQLQMTNLQREKEELNANLENTKNELKEKTKELNEVNEKLSKRSK 1635 Query: 317 EIANMT-ELTKKIELLEHLNCQIR---QTNKELENKLATMGTESKAVSSPSKKGSPLISR 372 EI + E+ +K + LN + Q N +LEN A + + + + KK + Sbjct: 1636 EIVQLRDEVNQKTVEISSLNDLVHNQNQVNAKLENTKAKLQEKEELLEISQKK----LRE 1691 Query: 373 KSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKD 432 S N K Q +E L ++ + N I KL I ++N+ DK + + Sbjct: 1692 ISSSNETFKENLNALQTENEQLKKENSE--NSENIRKLNEQISTINRQNEDKLLELKHNN 1749 Query: 433 TXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDE 492 K++ QLE + L + N + ++ +LK + N Sbjct: 1750 DALQNTIQNVTSKNS-----QLEADVQNKEKELQRLN------NLVTEISGELKSKENKA 1798 Query: 493 IKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFS---- 548 ++ I L S E++I QL +EI+ N N K+ N+ KL++ +K I+ + Sbjct: 1799 EDQKQQQNSI--LSSKEQEIKQLKEEINQLNSNSEKLVQNYNSKLEESEKKINKLNLKHG 1856 Query: 549 -KVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMEN 607 +V+ N ++ +++ E +SQ+ LEE+K NL +Y S D+ KK+ E+ N Sbjct: 1857 EEVTSLNTKLQQISSENKKISQEKTSLEEDKTNLSKENEEYKSQL---QDLKKKLEELNN 1913 Query: 608 LAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQ 651 + K I+ L+ + +E Q+ E E+++ +++ L+ Sbjct: 1914 TISDKEKEINDLKLHVVETTEEKG--TQEVAEEEEEVGEMAPLK 1955 >UniRef50_A0CWJ6 Cluster: Chromosome undetermined scaffold_3, whole genome shotgun sequence; n=2; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_3, whole genome shotgun sequence - Paramecium tetraurelia Length = 1259 Score = 172 bits (419), Expect = 6e-41 Identities = 250/1122 (22%), Positives = 518/1122 (46%), Gaps = 94/1122 (8%) Query: 477 EIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKS----- 531 E+A Q+ ++EL EI KD I+K+K EEQ QL E+D K +I+ + Sbjct: 114 ELANYQQHFEEELQLEITQ---KDYIDKIKGLEEQNQQLIHELDLVTKKLIESQRGSLNN 170 Query: 532 -NHKLKLKQMQKTIDNF-SKVSDSNKEIVRLTEELHHLSQK-----VAELEEEKGNLQLH 584 ++ + +Q ++ I++ K+ +K + + EEL + K + +L+ EK L Sbjct: 171 YDNNYQTQQYEQIIEDLQQKIEQLSKFLSQKDEELQQNNNKQYLVQIEQLQIEKITQSLQ 230 Query: 585 LVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKL 644 L +Y + + + ++ E N+ + +LK L S + +++Q+ +++Q K+ ++ Sbjct: 231 LEEYKNK---INKLQQEQEEKNNIID-QLKKNYSLNSSRNEIIQKQNMIQNKHQYIKID- 285 Query: 645 ADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKE 704 ++ +L D + + + + Q + S K +E K + Q L E Sbjct: 286 QNVLELSDDIETTVKRRTNFDYQAGKYNQSGKGF---LEQ-KSPRSQFSDQDSYLFL-CE 340 Query: 705 DIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYI 764 + LQ ++ DL +K + E L+ I E S + Q I+ + E Sbjct: 341 KLQQDLQTEEKQYNDLANKKQMADIEN-DRLINLIKELEYSIQEKQLLIEHQDNEIKSNQ 399 Query: 765 ENIESELSKYKSRICRLEESIAVMEDRRYSLER-KADQLGSYLQEKQKAYSEYTIQEDEL 823 NI + S++K I + ++ + + ED+ +LE + ++L Y Q+ + S+ Q+D Sbjct: 400 RNIRKKESEHKKTIIQQQDDMQIYEDKLNALENLRKEELRIYEQQISQIQSQLK-QKDIE 458 Query: 824 VNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNA--LVE 881 + +L ++ ++ + ENKE+Q+ QI ++ ++L+ ++ +QQ L + Sbjct: 459 LKKLQDQTKDKHKLQAKIQSLIEENKEIQQNIQIKDQKEEDLKTKVALLQQQLKTKELDK 518 Query: 882 KANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKE---IEDLEI-EFNTQI- 936 N + + ES Q +L +LE N+ I + QT I QK ++ +++ +I + Q+ Sbjct: 519 SQNSNRIYDLESQIIQLKL-ELEQNI--INAQLQTEINQKNEQQMKLKEFQINKLQDQLK 575 Query: 937 ESAIRDKKVLNEKYEKNIEYVTQLEAQ---LQEYKNNIENL-NMNVEELNKMNLELIDKH 992 E++ + K+++ E+ +N Q++ Q L++ + I+ L N+ + + NL + ++ Sbjct: 576 EASNKQKEIITERELENQRNYQQIDEQNDLLRKQEYEIKRLQNLISQRPLEKNLNIQSEN 635 Query: 993 -VQKQQTQSPDYTEQYINE-INKLNALLKQKDEEIIALNQK--INNAQVSYMSMVSDYES 1048 V K+Q + E + + + L LK KD+EII +QK ++NA++ ++ + Sbjct: 636 LVLKEQIEELLNQEANLEQKVIILETQLKGKDQEIIVTSQKQILSNAELQ-----TNMKK 690 Query: 1049 KLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPK 1108 + A F KL E+++Q++ K+ Q NE+L ++ D + +L E K E+ + Sbjct: 691 QEADFNDKLIEKEQQIQKLIKENQSLNQENEQLLHKIKNHDSRNAQL-EMKEQQELESHR 749 Query: 1109 TEGMIISSTIE--PMSDDANNVDXXXX----XXXXXXXXLKVQEEEEFIQERSVLQEQSA 1162 E I I+ P+SDD + L+ Q +++ IQ +VL +Q Sbjct: 750 LE---IQKKIDQIPLSDDGTTLSELNSYRMDELKTFASQLESQNKKDLIQ--TVL-DQKI 803 Query: 1163 KLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRS 1222 ++ + + ++ +E L +++ ++ ++Q ++SK +QL E ++ +++ L + Sbjct: 804 EMVQKNDQLNNQVQIIEELKSKIKMNEEELKDQRELVESKQKQL-AELNSFKQSISSLEN 862 Query: 1223 SISSAVDQRGFEIAELWKQHLAQREADF--QKTEHELRVQLSAFESKYEQLLDSVQSSTQ 1280 + V ++ + A+ + L Q++ QK ++E + Q ESK +L D +Q+ Q Sbjct: 863 QLK--VKEQSLKKAQEENKELQQQKQIVIQQKKQNETQQQ----ESK--KLQDVIQNQEQ 914 Query: 1281 EETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXX 1340 + K ++ KLQD+ L E+ + +NQ ++L+ E+E K A Sbjct: 915 QMKTKDENLK-------KLQDQLRELGKKNEQLSKDLNQNKVLKDEVEKYKNALNQKEEE 967 Query: 1341 XXXXXXXXXXDLRTENQSYK-QMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAE 1399 + ++Q K Q Q + +E + ++ ++N + Sbjct: 968 QKNLQNQISNQKKQDDQIKKLQQQLEKETKTKKEEIEKLQNEINELNQELQQAQQLNYNQ 1027 Query: 1400 AKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRI---EDLTYEKE 1456 K L Q++ ++ Q+T + L + +N++ QL E +++ E+ KE Sbjct: 1028 KK---LEDQVKKLQQQLDQQTEKSKKQLQDSEKKQQNLQNQLKETAEQLSEWEENDLTKE 1084 Query: 1457 SELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEV 1516 ++ L ++ E E QK+ + VK ++E +K E V++ Q + N E+ Sbjct: 1085 EQIQKLVRQVEEYKKKEEMFQKQG--KTVKELQE-QLKQAEKVNIELQKEKKNSQAEKNG 1141 Query: 1517 AKTNEMQ--TALENQEIEIVTLNDEITNLQNMVRASSSKIQK 1556 K N Q L+ Q ++ LN+E+ +N+++ K+Q+ Sbjct: 1142 QKENLEQEIKELKEQITKLQKLNNELVIYENIIQVDVRKMQE 1183 Score = 131 bits (317), Expect = 1e-28 Identities = 205/1045 (19%), Positives = 451/1045 (43%), Gaps = 111/1045 (10%) Query: 237 QRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLA 296 ++L K + KD + L++ + +I K+ Q L+ Sbjct: 192 EQLSKFLSQKDEELQQNNNKQYLVQIEQLQIE----KITQSLQLEEYKNKINKLQQEQEE 247 Query: 297 KQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTES 356 K +I ++ + + I + K + ++ ++ + + + ++E + Sbjct: 248 KNNIIDQLKKNYSLNSSRNEIIQKQNMIQNKHQYIK-IDQNVLELSDDIETTVKRRTNFD 306 Query: 357 KAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQD--TDKK-----INKNEIAK 409 ++ G + +KS R+ S S E L QD T++K NK ++A Sbjct: 307 YQAGKYNQSGKGFLEQKSPRSQFSDQDS--YLFLCEKLQQDLQTEEKQYNDLANKKQMAD 364 Query: 410 LEM-----VIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHME-GP 463 +E +I+ L + +K+ +I +D K++ + ++ Q M+ Sbjct: 365 IENDRLINLIKELEYSIQEKQLLIEHQDNEIKSNQRNIRKKESEHKKTIIQQQDDMQIYE 424 Query: 464 SLIHVGTNT--EDVN----EIAKVQEQLKQE------LNDEIKD-----VNVKDLIEKLK 506 ++ N E++ +I+++Q QLKQ+ L D+ KD ++ LIE+ K Sbjct: 425 DKLNALENLRKEELRIYEQQISQIQSQLKQKDIELKKLQDQTKDKHKLQAKIQSLIEENK 484 Query: 507 SAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHH 566 ++ I Q+ D+ + K + + +LK K++ K+ N +++ D +I++L EL Sbjct: 485 EIQQNI-QIKDQKEEDLKTKVALLQQ-QLKTKELDKS-QNSNRIYDLESQIIQLKLELEQ 541 Query: 567 --LSQKVAELEEEKGNLQLHLVDYDSGRMIE-----SDVYKKMI---EMENLAETRL--K 614 ++ ++ +K Q+ L ++ ++ + S+ K++I E+EN + + Sbjct: 542 NIINAQLQTEINQKNEQQMKLKEFQINKLQDQLKEASNKQKEIITERELENQRNYQQIDE 601 Query: 615 AISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEI-KSVHLEEQIDALSA 673 LL Q++++ + +++ Q+ E + + + +Q+ + + +LE+++ L Sbjct: 602 QNDLLRKQEYEIKRLQNLISQRPLEKNLNIQSENLVLKEQIEELLNQEANLEQKVIILET 661 Query: 674 SKK----ELALVIENLKLDKEQLYGTIKDLENDKEDIM----NKLQNYIQENMDLTDKLE 725 K E+ + + L +L +K E D D + ++Q I+EN L + E Sbjct: 662 QLKGKDQEIIVTSQKQILSNAELQTNMKKQEADFNDKLIEKEQQIQKLIKENQSLNQENE 721 Query: 726 KM--SAEKISELLAKINHEEQSKIQT-QFGIDAKIQERDLYIENIE-SELSKY-----KS 776 ++ + A++ +EQ ++++ + I KI + L + SEL+ Y K+ Sbjct: 722 QLLHKIKNHDSRNAQLEMKEQQELESHRLEIQKKIDQIPLSDDGTTLSELNSYRMDELKT 781 Query: 777 RICRLEES-----IAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLM 831 +LE I + D++ + +K DQL + +Q ++ S+ + E+EL ++ ++ Sbjct: 782 FASQLESQNKKDLIQTVLDQKIEMVQKNDQLNNQVQIIEELKSKIKMNEEELKDQRELVE 841 Query: 832 DHDRVVEKQLLEIEHENKELQK-KNQILLEEN--QNLQISLSDMQQHYNALVEKANRTDL 888 +KQL E+ + + +NQ+ ++E + Q ++QQ ++++ + + Sbjct: 842 SK----QKQLAELNSFKQSISSLENQLKVKEQSLKKAQEENKELQQQKQIVIQQKKQNET 897 Query: 889 AESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNE 948 + ES K Q +++ E +K + L + ++ +L + N Q+ + KVL + Sbjct: 898 QQQESKKLQDVIQNQEQQMKTKDENLKKL----QDQLRELGKK-NEQLSKDLNQNKVLKD 952 Query: 949 KYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYI 1008 + EK + Q E + + +N I N +++ K+ +L +K+ + E+ Sbjct: 953 EVEKYKNALNQKEEEQKNLQNQISNQKKQDDQIKKLQQQL-----EKETKTKKEEIEKLQ 1007 Query: 1009 NEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVS 1068 NEIN+LN L+Q + + NQK + D KL Q ++++ ++ Sbjct: 1008 NEINELNQELQQAQQ--LNYNQK----------KLEDQVKKLQQ------QLDQQTEKSK 1049 Query: 1069 KQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIIS-STIEPMSDDANN 1127 KQL DS++ + LQ ++E +Q+ E +E LT E I K + E M Sbjct: 1050 KQLQDSEKKQQNLQNQLKETAEQLSEWEENDLTKEEQIQKLVRQVEEYKKKEEMFQKQGK 1109 Query: 1128 VDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTG 1187 + ++ ++E ++ Q L E++E +I +L+ LN EL Sbjct: 1110 TVKELQEQLKQAEKVNIELQKEKKNSQAEKNGQKENLEQEIKELKEQITKLQKLNNELVI 1169 Query: 1188 HDVVNQEQINQLKSKLEQLNTENDN 1212 ++ + Q + +++ ++ +N Sbjct: 1170 YENIIQVDVRKMQELQRKIECLENN 1194 Score = 112 bits (269), Expect = 9e-23 Identities = 172/848 (20%), Positives = 389/848 (45%), Gaps = 79/848 (9%) Query: 295 LAKQSIE-PSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIR-QTNKELENKLATM 352 L ++ IE +++T+ + K +I ++ E K+I+ N QI+ Q ++L+ K+A + Sbjct: 452 LKQKDIELKKLQDQTKDKHKLQAKIQSLIEENKEIQQ----NIQIKDQKEEDLKTKVALL 507 Query: 353 GTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEM 412 + K + S I + K++ + ++++ + K + ++ + ++ Sbjct: 508 QQQLKTKELDKSQNSNRIYDLESQIIQLKLELEQNIINAQLQTEINQKNEQQMKLKEFQI 567 Query: 413 -VIQSLNKDLVDKEY-VISEKDTXXXXXXXXXXGKDTLIA--QLQLEHQQHMEGPSLIHV 468 +Q K+ +K+ +I+E++ ++ L+ + +++ Q++ + Sbjct: 568 NKLQDQLKEASNKQKEIITERELENQRNYQQIDEQNDLLRKQEYEIKRLQNLISQRPLEK 627 Query: 469 GTNTEDVNEIAK--VQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAAN--K 524 N + N + K ++E L QE N E K + ++ + K K E +T + A Sbjct: 628 NLNIQSENLVLKEQIEELLNQEANLEQKVIILETQL-KGKDQEIIVTSQKQILSNAELQT 686 Query: 525 NMIKVKSNHKLKLKQMQKTIDNFSKVSDS-NKEIVRLTEELHHLSQKVAELE-EEKGNLQ 582 NM K +++ KL + ++ I K + S N+E +L ++ + + A+LE +E+ L+ Sbjct: 687 NMKKQEADFNDKLIEKEQQIQKLIKENQSLNQENEQLLHKIKNHDSRNAQLEMKEQQELE 746 Query: 583 LHLVDYDS--GRMIESDVYKKMIEMENLAETRLKAI-SLLESQ-KFDLVQELHILQQKYD 638 H ++ ++ SD + E+ + LK S LESQ K DL+Q +L QK + Sbjct: 747 SHRLEIQKKIDQIPLSDDGTTLSELNSYRMDELKTFASQLESQNKKDLIQT--VLDQKIE 804 Query: 639 EVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKD 698 V+ ++DQ+ ++++ + EE + +++EL E ++ ++QL + Sbjct: 805 MVQ---------KNDQLNNQVQII--EELKSKIKMNEEELKDQRELVESKQKQL----AE 849 Query: 699 LENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQ 758 L + K+ I + L+N + K+++ S +K E ++ ++Q IQ + + + Q Sbjct: 850 LNSFKQSI-SSLENQL--------KVKEQSLKKAQEENKELQQQKQIVIQQKKQNETQQQ 900 Query: 759 ERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTI 818 E + I+++ + K++ +E++ ++D+ L +K +QL L + + E Sbjct: 901 ESKKLQDVIQNQEQQMKTK----DENLKKLQDQLRELGKKNEQLSKDLNQNKVLKDEV-- 954 Query: 819 QEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNA 878 ++ N L + + ++ Q+ + ++ +++K Q L +E + + + +Q N Sbjct: 955 --EKYKNALNQKEEEQKNLQNQISNQKKQDDQIKKLQQQLEKETKTKKEEIEKLQNEINE 1012 Query: 879 LVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIES 938 L ++ + K + Q++ L+ L + T + + + +K+ ++L+ + E Sbjct: 1013 LNQELQQAQQLNYNQKKLEDQVKKLQQQLDQQTEKSKKQLQDSEKKQQNLQNQLKETAEQ 1072 Query: 939 AIR------DKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKH 992 K+ +K + +E + E Q+ ++ L +++ K+N+EL K Sbjct: 1073 LSEWEENDLTKEEQIQKLVRQVEEYKKKEEMFQKQGKTVKELQEQLKQAEKVNIEL-QKE 1131 Query: 993 VQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQ 1052 + Q + E EI +L E+I L QK+NN V Y +++ K+ + Sbjct: 1132 KKNSQAEKNGQKENLEQEIKELK-------EQITKL-QKLNNELVIYENIIQVDVRKMQE 1183 Query: 1053 FTTKLENME-EEMQRVSKQLLDSKQH--NEELQI----LVREQDDQIKELKETKLTFEMN 1105 K+E +E + Q+ SKQ +++K QI ++++ DQI ++ +L + + Sbjct: 1184 LQRKIECLENNQSQQGSKQNIETKSQGVTPRKQIRGSSVMKQNQDQISQMTLEQL--QQH 1241 Query: 1106 IPKTEGMI 1113 + K E +I Sbjct: 1242 VKKLEQII 1249 Score = 100 bits (240), Expect = 3e-19 Identities = 188/1041 (18%), Positives = 430/1041 (41%), Gaps = 65/1041 (6%) Query: 597 DVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVC 656 D+ +++ + N E + +LL +K +QE L++ D + + ++S++ Q+C Sbjct: 20 DMEQRLNAVINANEKLISLQTLLLKEK---IQENDQLKENIDILYNNNQELSEINI-QLC 75 Query: 657 SEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQE 716 +IK ++ + E+ + LK E + ++L N ++ +LQ I + Sbjct: 76 EQIKRCKNQKCASLHQKNHNEMERELTQLK---ELIVSKDRELANYQQHFEEELQLEITQ 132 Query: 717 NMDLTDK---LEKMSAEKISEL--LAKINHEEQSKIQTQFGIDAKIQERDLYIENIESEL 771 D DK LE+ + + I EL + K E Q + + + Q+ + IE+++ ++ Sbjct: 133 K-DYIDKIKGLEEQNQQLIHELDLVTKKLIESQRGSLNNYDNNYQTQQYEQIIEDLQQKI 191 Query: 772 SKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTI----QEDELVNRL 827 + + + +E + +++Y ++ + Q+ Q Q + I QE E N + Sbjct: 192 EQLSKFLSQKDEELQQNNNKQYLVQIEQLQIEKITQSLQLEEYKNKINKLQQEQEEKNNI 251 Query: 828 AVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTD 887 + + + EI + +Q K+Q + + +QN+ + LSD V++ D Sbjct: 252 IDQLKKNYSLNSSRNEIIQKQNMIQNKHQYI-KIDQNV-LELSD---DIETTVKRRTNFD 306 Query: 888 LAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLN 947 + + + +S + + + L + +K + +DL+ E Q K++ + Sbjct: 307 YQAGKYNQSGKGFLEQKSPRSQFSDQDSYLFLCEKLQ-QDLQTE-EKQYNDLANKKQMAD 364 Query: 948 EKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQY 1007 + ++ I + +LE +QE + IE+ + ++ N+ N+ + +K Q D + Y Sbjct: 365 IENDRLINLIKELEYSIQEKQLLIEHQDNEIKS-NQRNIRKKESEHKKTIIQQQDDMQIY 423 Query: 1008 INEINKLNALLKQK----DEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEE 1063 +++N L L K++ +++I + ++ + + + D + K++++ EE Sbjct: 424 EDKLNALENLRKEELRIYEQQISQIQSQLKQKDIE-LKKLQDQTKDKHKLQAKIQSLIEE 482 Query: 1064 MQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSD 1123 + + + + Q E+L+ V Q+K + K I E II +E + Sbjct: 483 NKEIQQNIQIKDQKEEDLKTKVALLQQQLKTKELDKSQNSNRIYDLESQIIQLKLE-LEQ 541 Query: 1124 DANNVDXXXXXXXXXXXXLKVQE----------------EEEFIQERSVLQEQSAKLNTE 1167 + N +K++E ++E I ER + +++ + E Sbjct: 542 NIINAQLQTEINQKNEQQMKLKEFQINKLQDQLKEASNKQKEIITERELENQRNYQQIDE 601 Query: 1168 LQECYTK----IIQLETLNTELTGHDVVNQEQINQ-LKSKLEQLNTENDNLLSTVAELRS 1222 + K I +L+ L ++ +N + N LK ++E+L + NL V L + Sbjct: 602 QNDLLRKQEYEIKRLQNLISQRPLEKNLNIQSENLVLKEQIEELLNQEANLEQKVIILET 661 Query: 1223 SISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEE 1282 + DQ ++ A+ + + +K E + +L E + ++L+ QS QE Sbjct: 662 QLKGK-DQEIIVTSQKQILSNAELQTNMKKQEADFNDKLIEKEQQIQKLIKENQSLNQEN 720 Query: 1283 TNKIVTMEQVTSLQNKLQDKEE-----HLRNLQEKYADV-INQIEILRSEIEDEKVAFXX 1336 + ++ S +L+ KE+ H +Q+K + ++ SE+ ++ Sbjct: 721 EQLLHKIKNHDSRNAQLEMKEQQELESHRLEIQKKIDQIPLSDDGTTLSELNSYRMDELK 780 Query: 1337 XXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVN 1396 +Q + +Q+ LN + + KS + Sbjct: 781 TFASQLESQNKKDLIQTVLDQKIEMVQKNDQLNNQVQIIEELKSKIKMNEEELKDQRELV 840 Query: 1397 DAEAKVL-EL-THQLELKDSEIYQKTHEYTITLTQR-NDEFENVRQQLVEYEKRIEDLTY 1453 +++ K L EL + + + E K E ++ Q N E + +Q +++ +K+ E Sbjct: 841 ESKQKQLAELNSFKQSISSLENQLKVKEQSLKKAQEENKELQQQKQIVIQQKKQNETQQQ 900 Query: 1454 EKESELAILRLKMHENANHYETMQK-ESEIERV-KLIEELNVKITESVSLNKQVAELNKA 1511 E + +++ + + E ++K + ++ + K E+L+ + ++ L +V + A Sbjct: 901 ESKKLQDVIQNQEQQMKTKDENLKKLQDQLRELGKKNEQLSKDLNQNKVLKDEVEKYKNA 960 Query: 1512 LEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQG-RDE 1570 L ++ + +Q + NQ+ + + L+ + +I+K + ++ Q + Sbjct: 961 LNQKEEEQKNLQNQISNQKKQDDQIKKLQQQLEKETKTKKEEIEKLQNEINELNQELQQA 1020 Query: 1571 QLDNTMNKELLDAVPRAELDL 1591 Q N K+L D V + + L Sbjct: 1021 QQLNYNQKKLEDQVKKLQQQL 1041 Score = 58.8 bits (136), Expect = 1e-06 Identities = 132/703 (18%), Positives = 294/703 (41%), Gaps = 71/703 (10%) Query: 933 NTQIESAIRDKKVLNEKYEKNIEYVTQL-EAQLQE---YKNNIENLNMNVEELNKMNLEL 988 NT + R V+N EK I T L + ++QE K NI+ L N +EL+++N++L Sbjct: 16 NTIDDMEQRLNAVINAN-EKLISLQTLLLKEKIQENDQLKENIDILYNNNQELSEINIQL 74 Query: 989 ID--KHVQKQQTQS--PDYTEQYINEINKLNALLKQKDEEIIALNQ------KINNAQVS 1038 + K + Q+ S + E+ +L L+ KD E+ Q ++ Q Sbjct: 75 CEQIKRCKNQKCASLHQKNHNEMERELTQLKELIVSKDRELANYQQHFEEELQLEITQKD 134 Query: 1039 YMSMVSDYESKLAQFTTKLENMEE---EMQRVS-------------KQLL-DSKQHNEEL 1081 Y+ + E + Q +L+ + + E QR S +Q++ D +Q E+L Sbjct: 135 YIDKIKGLEEQNQQLIHELDLVTKKLIESQRGSLNNYDNNYQTQQYEQIIEDLQQKIEQL 194 Query: 1082 QILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXX 1141 + ++D+++++ + ++ + E + S +E + N + Sbjct: 195 SKFLSQKDEELQQNNNKQYLVQIEQLQIEKITQSLQLEEYKNKINKLQQEQEEKNNIIDQ 254 Query: 1142 LKV-----QEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQI 1196 LK E IQ+++++Q + + + Q +ET T D + Sbjct: 255 LKKNYSLNSSRNEIIQKQNMIQNKHQYIKID-QNVLELSDDIETTVKRRTNFDYQAGKYN 313 Query: 1197 NQLKSKLEQLN-----TENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREAD-- 1249 K LEQ + ++ D+ L +L+ + + Q ++A K+ +A E D Sbjct: 314 QSGKGFLEQKSPRSQFSDQDSYLFLCEKLQQDLQTEEKQYN-DLAN--KKQMADIENDRL 370 Query: 1250 ---FQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHL 1306 ++ E+ ++ + E + ++ + ++ ++E+ T+ Q +DK L Sbjct: 371 INLIKELEYSIQEKQLLIEHQDNEIKSNQRNIRKKESEHKKTIIQQQDDMQIYEDKLNAL 430 Query: 1307 RNLQEK----YADVINQI--EILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYK 1360 NL+++ Y I+QI ++ + +IE +K+ + E Q Sbjct: 431 ENLRKEELRIYEQQISQIQSQLKQKDIELKKLQDQTKDKHKLQAKIQSLIEENKEIQQNI 490 Query: 1361 QMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKT 1420 Q+++Q ++ + A L++ R+ D E+++++L +LEL+ + I Sbjct: 491 QIKDQKEEDLKTKVALLQQQLKTKELDKSQNSNRIYDLESQIIQL--KLELEQNII---N 545 Query: 1421 HEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKES 1480 + + Q+N++ +++ + K + L + I+ + EN +Y+ + +++ Sbjct: 546 AQLQTEINQKNEQQMKLKE--FQINKLQDQLKEASNKQKEIITERELENQRNYQQIDEQN 603 Query: 1481 EIERVK--LIEELNVKITE-SVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLN 1537 ++ R + I+ L I++ + N + N L+E++ E+ N E +++ L Sbjct: 604 DLLRKQEYEIKRLQNLISQRPLEKNLNIQSENLVLKEQI---EELLNQEANLEQKVIILE 660 Query: 1538 DEITNL-QNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKE 1579 ++ Q ++ S +I + ++ K+ + D + KE Sbjct: 661 TQLKGKDQEIIVTSQKQILSNAELQTNMKKQEADFNDKLIEKE 703 Score = 56.0 bits (129), Expect = 8e-06 Identities = 88/407 (21%), Positives = 176/407 (43%), Gaps = 45/407 (11%) Query: 212 EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271 E+ K ++ KM E + + E + KQ+ L ++ S ISSLE K+ E + + E+ Sbjct: 820 EELKSKI-KMNEEELKDQRELVESKQKQLAELNSFKQSISSLENQLKVKEQSLKKAQEEN 878 Query: 272 SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTK-KIEL 330 +L Q+ + K+ E +E ++++ I N + K K E Sbjct: 879 KELQQQKQ------------IVIQQKKQNETQQQESKKLQD----VIQNQEQQMKTKDEN 922 Query: 331 LEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSG-----RNTASKMKSP 385 L+ L Q+R+ K+ E +L+ ++K + +K +++K +N S K Sbjct: 923 LKKLQDQLRELGKKNE-QLSKDLNQNKVLKDEVEKYKNALNQKEEEQKNLQNQISNQKKQ 981 Query: 386 WSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGK 445 Q+ + + K K EI KL+ I LN++L + + + Sbjct: 982 DDQIKKLQQQLEKETKTKKEEIEKLQNEINELNQELQQAQQLNYNQKKLEDQVKK----- 1036 Query: 446 DTLIAQLQLEHQQHMEGPSLIHVGTNTEDV-NEIAKVQEQLKQ-ELNDEIKDVNVKDLIE 503 Q QL+ Q L +++ N++ + EQL + E ND K+ ++ L+ Sbjct: 1037 ----LQQQLDQQTEKSKKQLQDSEKKQQNLQNQLKETAEQLSEWEENDLTKEEQIQKLVR 1092 Query: 504 KLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEE 563 +++ +++ + + ++K K+ + ++QK N + KE L +E Sbjct: 1093 QVEEYKKKEEMFQKQGKTVKELQEQLKQAEKVNI-ELQKEKKNSQAEKNGQKE--NLEQE 1149 Query: 564 LHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAE 610 + L +++ +L++ L LV Y++ +I+ DV +KM E++ E Sbjct: 1150 IKELKEQITKLQK----LNNELVIYEN--IIQVDV-RKMQELQRKIE 1189 >UniRef50_UPI00015A55AB Cluster: UPI00015A55AB related cluster; n=1; Danio rerio|Rep: UPI00015A55AB UniRef100 entry - Danio rerio Length = 2213 Score = 172 bits (418), Expect = 8e-41 Identities = 285/1420 (20%), Positives = 616/1420 (43%), Gaps = 104/1420 (7%) Query: 212 EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271 E +++ K +E+F + + K EK+ L K + + ++ L++ LE R IS + Sbjct: 165 EKMTEELKKEKESFTHLAEDTKTEKKILDKMKVANESLMADLQKEKSNLEEMRENISKQT 224 Query: 272 SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEI-ANMTELTKKIEL 330 +E E+ + KQ E EK+ E++ +E+ E+ K E Sbjct: 225 EDSEKEKEKIRLREDELEQLQAEIHKQQGEIKM-EKSNNEKQMKIELEREAVEIRKIKEE 283 Query: 331 LEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLS 390 +++ + + + L+ + E + + + + R KM ++ Sbjct: 284 IQNERQNLEKMTEALKEEREAFENEKEVLKQMKTELEREAEIQKEREDLEKMNENITREM 343 Query: 391 SETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIA 450 E +Q+ ++E+ +L+ IQ+L ++L +KE I KD + Sbjct: 344 HEIKHQEEQMNQKQDELDQLKTEIQNLQQEL-EKEKEIIMKDRSQLD-----------LR 391 Query: 451 QLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVN-VKDLIEKLKSAE 509 Q +L+ QQ + + + +++ + E+ KQE+ E ++ N ++ + +L+ Sbjct: 392 QSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKEREEKNKLEQMKIELEREA 451 Query: 510 EQITQLNDEIDAANKNMIKVK---SNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEE--L 564 ++I+++ +E + + K+ N K +KQM KT D + + KE + +E L Sbjct: 452 DEISKIKEETQNKRQRLEKMTEAFENEKEAMKQM-KT-DLQIQADEIVKEDLEKQKENTL 509 Query: 565 HHLSQKVAELEEEKGNL--QLHLVDYDSGRM--IESDVYKKMIEMENLAE--TRLKAISL 618 + ++ ++E+ N+ ++H + + +M + ++ + E++NL + + K I + Sbjct: 510 AEIQKEREDVEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEIIM 569 Query: 619 LESQKFDLVQ-ELHILQQKYDEVEDKLA-DISQLQSDQVCSEIKSVHLEEQIDALSASKK 676 + +FDL Q EL Q +++ + + + QL D+ E + +E++ S+K Sbjct: 570 KDRSQFDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKEKHDFDQSRK 629 Query: 677 ELALVIENLKLDK---EQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAE--K 731 L ++ +KL K E+ ++ ++ + E ++++ +E + LEKM+ E K Sbjct: 630 SLDKDLKMMKLQKQVFEEEKNKLEQMKIELEREADEIRKIKEETQNERQSLEKMTEELKK 689 Query: 732 ISELLAKINHEEQSKIQTQFGIDAKIQE--RDLYIENIESELSKYKSRICRLEESIAVME 789 E + ++ + + A+IQ+ DL ++ +S L + K I + E I + Sbjct: 690 EKESFTHLAEVKEDLEKQKENTLAQIQKEREDLDLQKEKSNLEEMKENISKQTEDIEKEK 749 Query: 790 DRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENK 849 D+ + + D+L E K SE I++ + A ++ ++ +++ ++ + + Sbjct: 750 DK---IRLREDELEQLQAEIHKQQSETEIEKSNIERERAAIIKDVEDLQSKIISLDRDAE 806 Query: 850 ELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKR 909 L+ + E + L+ +++++ + + + T + + +N ++ Sbjct: 807 SLKLDREAFENEKEELKQMKTELEREADEIEKIKLETQHERQRVEEMTADFMETMNNERK 866 Query: 910 ITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNI----EYVTQLEAQLQ 965 +++ +I ++K+E+E + + +S D K++ + E + E + Q + ++ Sbjct: 867 QLDKNKVMIEEQKQEMEKKRDDMDQSRKSLDEDLKMMKAQKESELAKLQEDILQQQQEMD 926 Query: 966 EYKNNIE-NLNMNVEELNKMNLELID-KHVQKQQTQSPDYTEQYINEINKLNALLKQKDE 1023 E K ++E + +E+ + + +D ++V++ +T+ D E +L +E Sbjct: 927 EQKQDLERERDELLEQWRLVETQKMDNENVKQLKTELLDEKESTEKIRKQLEQDKAYMEE 986 Query: 1024 EIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEE-LQ 1082 + L++++ + + D E + Q K+E+ E E+Q+ K+L S++ E+ +Q Sbjct: 987 NKLNLHKELEELNLQKQG-IQDKEEMVKQ---KIES-EREIQQEKKKLQRSEEELEDKMQ 1041 Query: 1083 ILVREQDDQIKELKETKLTFEMNIPKTEGM-IISSTIEPMSDDANNVDXXXXXXXXXXXX 1141 + RE +Q K+L + + I K + M I S I +++ N Sbjct: 1042 KIKREMIEQKKDLDQ---KMKQVIRKRDEMEKIRSDIANATEEINRERQELEILRNNVQS 1098 Query: 1142 LKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKS 1201 + E + ++ E+SA + E +E +I E + E T D+ Q+ +L+S Sbjct: 1099 ARHDFELLLERTANLEDEESAATDIERRELVEAVIDKEEMK-EFT--DI--QKYKEELQS 1153 Query: 1202 KLEQLNTEN---DNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELR 1258 E+L T+ D L S V +LR +I E+ QH ++ A+ + EL+ Sbjct: 1154 VTEELLTKKRDLDQLNSDVQDLRQTIE-----------EINIQH-GKKRAELEGIGFELK 1201 Query: 1259 VQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTS--LQNKLQDKEEHLRNLQEKYADV 1316 E + ++L ++ +E NK ++E++ L+++LQ + E L +K Sbjct: 1202 KGEQLLEKQKDELKEN-GWIVEEIKNKKDSLEKINMEILRSELQRQREDLETSIQKLTHE 1260 Query: 1317 INQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQ 1376 ++E+LRSEI EK DL + QMQ Q I N E Sbjct: 1261 KREMEVLRSEIVLEKKDLDQKMKQDANSESDRLKDLSMK----LQMQRQDIEKTNTEMET 1316 Query: 1377 LKKSSXXXXXXXXXXXXRV-NDAEAKVLELTHQLELKDSEIYQKTHEYTI----TLTQRN 1431 K+S R+ ND +A ++TH LELK E+ ++ + L +RN Sbjct: 1317 KKRSLDRMSRELQDDKIRLKNDRDAYEKDMTH-LELKREELQREQEALEVMKVDILKKRN 1375 Query: 1432 D---EFENV---RQQLV-----EYEKRIEDLTYEKESELAILRLKMHENANHYETMQKES 1480 + E ENV RQ+L+ ++ K+ + T E +LA + + N Y + +E Sbjct: 1376 EFAKEMENVHSERQKLLLLQEQKHLKQAKAETEECRKQLAEMSETVTTEQNEYRKLIEEL 1435 Query: 1481 EIERVKLIEELNVKITESVSLNKQVAELNKALEEEV----AKTNEMQTALENQEIEIVTL 1536 + E+ +L N E L + L + E++ + + +E + + Sbjct: 1436 QREKEQLEISKNQIEQEKKDLQNMKSNLERKEREDLENCWVEIEGEKKRMEEETRRLEMH 1495 Query: 1537 NDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTM 1576 +EI + + ++ +++ + + KQ +E+ +N M Sbjct: 1496 REEIKKVDSELQKKKKELEDQMMDLTREKQETEEERNNLM 1535 Score = 170 bits (413), Expect = 3e-40 Identities = 321/1659 (19%), Positives = 682/1659 (41%), Gaps = 144/1659 (8%) Query: 5 KNIDHPSEMELSEETTARLPSSEVSSV-AGXXXXXXXXXXXXXXXERQIKFERAQKCLEN 63 +NI +E E+ RL E+ + A E+Q+K E LE Sbjct: 218 ENISKQTEDSEKEKEKIRLREDELEQLQAEIHKQQGEIKMEKSNNEKQMKIE-----LER 272 Query: 64 AALVSKRIKEHRKATAELLGRPFVPGISESLANTLKQKEILMEKIKQYKELSKRSSTTIV 123 A+ ++IKE + + L E + LK++ E + KE+ K+ T + Sbjct: 273 EAVEIRKIKEEIQNERQNL---------EKMTEALKEER---EAFENEKEVLKQMKTELE 320 Query: 124 RXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKD 183 R + ++T + IK ++ ++ Q ++ ++T I +LQ+++ ++ Sbjct: 321 REAEIQKEREDLEKMNE--NITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEK 378 Query: 184 QIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKD-EKQRLLKD 242 +II E K + ++ ++ ME + ++ EK+R K+ Sbjct: 379 EIIMKDRSQLDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKEREEKN 438 Query: 243 -IESKDVRIS-SLEEANKLLEAA---RFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAK 297 +E + + +E +K+ E R + E E + K Sbjct: 439 KLEQMKIELEREADEISKIKEETQNKRQRLEKMTEAFENEKEAMKQMKTDLQIQADEIVK 498 Query: 298 QSIEPSCEEKTEIEEKGSLEIANMTE-LTKKIELLEHLNCQIRQTNKELENKLATMGTES 356 + +E E +K ++ M E +T+++ ++H Q+ Q EL+ + TE Sbjct: 499 EDLEKQKENTLAEIQKEREDVEKMNENITREMHEIKHQEEQMNQKQDELDQ----LKTEI 554 Query: 357 KAVSSPSKKGSPLISRKSGR-----NTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLE 411 + + +K +I + + + K ++ + + N+ +K E+ + + Sbjct: 555 QNLQQELEKEKEIIMKDRSQFDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQK 614 Query: 412 MVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKD-TLIAQLQLEHQQHMEGPSLIHVGT 470 ++ D D+ +KD ++ + Q+++E ++ + I T Sbjct: 615 QEMEKEKHDF-DQSRKSLDKDLKMMKLQKQVFEEEKNKLEQMKIELEREADEIRKIKEET 673 Query: 471 NTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVK 530 E + K+ E+LK+E VK+ +EK K E + Q+ E + + ++ K K Sbjct: 674 QNER-QSLEKMTEELKKEKESFTHLAEVKEDLEKQK--ENTLAQIQKERE--DLDLQKEK 728 Query: 531 SNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHL--VDY 588 SN L++M++ I ++ + K+ +RL E+ L Q AE+ +++ ++ ++ Sbjct: 729 SN----LEEMKENISKQTEDIEKEKDKIRLRED--ELEQLQAEIHKQQSETEIEKSNIER 782 Query: 589 DSGRMIES--DVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDE------- 639 + +I+ D+ K+I ++ AE+ E++K +L Q L+++ DE Sbjct: 783 ERAAIIKDVEDLQSKIISLDRDAESLKLDREAFENEKEELKQMKTELEREADEIEKIKLE 842 Query: 640 -------VEDKLADI--------SQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIEN 684 VE+ AD QL ++V E + +E++ D + S+K L ++ Sbjct: 843 TQHERQRVEEMTADFMETMNNERKQLDKNKVMIEEQKQEMEKKRDDMDQSRKSLDEDLKM 902 Query: 685 LKLDKE-QLYGTIKDLENDKEDIMNKLQNYIQENMDLTDK-----LEKMSAEKISELLAK 738 +K KE +L +D+ ++++ + Q+ +E +L ++ +KM E + +L + Sbjct: 903 MKAQKESELAKLQEDILQQQQEMDEQKQDLERERDELLEQWRLVETQKMDNENVKQLKTE 962 Query: 739 INHEEQS--KIQTQFGID-AKIQERDLYIENIESELSKYKSRICRLEESIA--VMEDRRY 793 + E++S KI+ Q D A ++E L + EL+ K I EE + + +R Sbjct: 963 LLDEKESTEKIRKQLEQDKAYMEENKLNLHKELEELNLQKQGIQDKEEMVKQKIESEREI 1022 Query: 794 SLERKADQLGSY-LQEK-QKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKEL 851 E+K Q L++K QK E Q+ +L ++ ++ +EK +I + +E+ Sbjct: 1023 QQEKKKLQRSEEELEDKMQKIKREMIEQKKDLDQKMKQVIRKRDEMEKIRSDIANATEEI 1082 Query: 852 QKKNQILLEENQNLQISLSD----MQQHYNALVEKANRTDLAESESTKYQTQLRDLE--S 905 ++ Q L N+Q + D +++ N E++ TD+ E + +++ + Sbjct: 1083 NRERQELEILRNNVQSARHDFELLLERTANLEDEESAATDIERRELVEAVIDKEEMKEFT 1142 Query: 906 NLKRITHEHQTL---IVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYV----- 957 ++++ E Q++ ++ KK++++ L + + I + + + K +E + Sbjct: 1143 DIQKYKEELQSVTEELLTKKRDLDQLNSDVQ-DLRQTIEEINIQHGKKRAELEGIGFELK 1201 Query: 958 ---TQLEAQLQEYKNN---IENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEI 1011 LE Q E K N +E + + L K+N+E++ +Q+Q+ ++ +E Sbjct: 1202 KGEQLLEKQKDELKENGWIVEEIKNKKDSLEKINMEILRSELQRQREDLETSIQKLTHEK 1261 Query: 1012 NKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQL 1071 ++ L + E L+QK+ S + D KL +E EM+ K+ Sbjct: 1262 REMEVLRSEIVLEKKDLDQKMKQDANSESDRLKDLSMKLQMQRQDIEKTNTEME-TKKRS 1320 Query: 1072 LDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXX 1131 LD + + EL QDD+I+ LK + +E ++ E E + + VD Sbjct: 1321 LD--RMSREL------QDDKIR-LKNDRDAYEKDMTHLELKREELQREQEALEVMKVDIL 1371 Query: 1132 XXXXXXXXXXLKVQEEEEFIQERSVLQEQS--AKLNTELQECYTKIIQL-ETLNTELTGH 1188 V E Q+ +LQEQ + E +EC ++ ++ ET+ TE + Sbjct: 1372 KKRNEFAKEMENVHSER---QKLLLLQEQKHLKQAKAETEECRKQLAEMSETVTTEQNEY 1428 Query: 1189 DVVNQE---QINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQ 1245 + +E + QL+ Q+ E +L + + L ++ EI E K+ + + Sbjct: 1429 RKLIEELQREKEQLEISKNQIEQEKKDLQNMKSNLERKEREDLENCWVEI-EGEKKRMEE 1487 Query: 1246 READFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEH 1305 + E++ S + K ++L D + T+E+ + +L+N+L+D + Sbjct: 1488 ETRRLEMHREEIKKVDSELQKKKKELEDQMMDLTREKQETEEERNNLMALKNQLEDLRKE 1547 Query: 1306 LRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQ 1365 ++EK + IE ++ +I ++ R E + KQM E Sbjct: 1548 NEIVKEKLTLEKSNIEEMQLKIFKQQ-RLNDQTREENKKEKESLEQQRFETEQQKQMLEI 1606 Query: 1366 SILNINEEN---AQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQK--- 1419 S + EE A L + + N +V ++ +L + I Q+ Sbjct: 1607 STTKMMEEKNEMADLSRELQKAKDELEKIAYKTNKERHEVEQMQAELHSQIQAIEQQGQI 1666 Query: 1420 THEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKE---SELAILRLKMHENANHYETM 1476 + L ++ + R+Q + EK D+ + + + +L + + + E + Sbjct: 1667 MQDKQNHLEEKELSIQKTRRQKEDLEKMSTDIKEQNQDLMKQRDLLEQEKEDIKSELERV 1726 Query: 1477 QKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTL 1536 + E + E+ KL + + + E L K +E+ K ++ + +E+ ++ +E Sbjct: 1727 RSEIDHEQKKLNDYMKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDNKIQQTNLE---- 1782 Query: 1537 NDEITNLQNMVRASSSKIQKHVSFASD-TKQGRDEQLDN 1574 +I + +V ++++ D TKQ +E+ ++ Sbjct: 1783 KHDIEKSKEIVEKLMVEVEEQSKQREDLTKQEMEEEKED 1821 Score = 167 bits (406), Expect = 2e-39 Identities = 278/1497 (18%), Positives = 653/1497 (43%), Gaps = 101/1497 (6%) Query: 152 KEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXX 211 K+K+N L+ +Q E LDLQ++ + +++ E +K T Sbjct: 706 KQKENTLAQIQ-----KEREDLDLQKEKSNLEEMKENISKQTEDIEKEKDKIRLREDEL- 759 Query: 212 EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLE-EANKL-LEAARFEISL 269 E + ++ K Q ++ + E+ ++KD+E +I SL+ +A L L+ FE Sbjct: 760 EQLQAEIHKQQSETEIEKSNIERERAAIIKDVEDLQSKIISLDRDAESLKLDREAFENEK 819 Query: 270 EHSK-LAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEE--KTEIEEKGSLEIANMTELTK 326 E K + ELE+ +Q +E + +T E+ L+ N + + Sbjct: 820 EELKQMKTELEREADEIEKIKLETQH-ERQRVEEMTADFMETMNNERKQLD-KNKVMIEE 877 Query: 327 KIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASK-MKSP 385 + + +E + Q+ K L+ L M + + S +K ++ ++ + + ++ Sbjct: 878 QKQEMEKKRDDMDQSRKSLDEDLKMMKAQKE--SELAKLQEDILQQQQEMDEQKQDLERE 935 Query: 386 WSQLSSETLNQDTDKKINKN-EIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXG 444 +L + +T K N+N + K E++ + + + + K+ E+D Sbjct: 936 RDELLEQWRLVETQKMDNENVKQLKTELLDEKESTEKIRKQL---EQDKAYMEENKLNLH 992 Query: 445 KDTLIAQLQLEHQQHMEGPSLIHVGTNTE-DVNEIAKVQEQLKQELNDEIKDVNVKDLIE 503 K+ + +L L+ Q + ++ +E ++ + K ++ ++EL D+++ + +++IE Sbjct: 993 KE--LEELNLQKQGIQDKEEMVKQKIESEREIQQEKKKLQRSEEELEDKMQKIK-REMIE 1049 Query: 504 KLKSAEEQITQL---NDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRL 560 + K ++++ Q+ DE++ ++ + ++++ +N + ++ Sbjct: 1050 QKKDLDQKMKQVIRKRDEMEKIRSDIANATEEINRERQELEILRNNVQSARHDFELLLER 1109 Query: 561 TEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAE---TRLKAIS 617 T L ++ A + E+ L ++D + + +D+ K E++++ E T+ + + Sbjct: 1110 TANLE--DEESAATDIERRELVEAVIDKEEMKEF-TDIQKYKEELQSVTEELLTKKRDLD 1166 Query: 618 LLESQKFDLVQELHILQQKYDEVEDKLADIS-QLQSDQVCSEIKSVHLEEQ---IDAL-- 671 L S DL Q + + ++ + +L I +L+ + E + L+E ++ + Sbjct: 1167 QLNSDVQDLRQTIEEINIQHGKKRAELEGIGFELKKGEQLLEKQKDELKENGWIVEEIKN 1226 Query: 672 ---SASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEK-- 726 S K + ++ L+ +E L +I+ L ++K ++ + E DL K+++ Sbjct: 1227 KKDSLEKINMEILRSELQRQREDLETSIQKLTHEKREMEVLRSEIVLEKKDLDQKMKQDA 1286 Query: 727 -MSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESI 785 ++++ +L K+ + Q +T ++ K + D ++ + + K+ E+ + Sbjct: 1287 NSESDRLKDLSMKLQMQRQDIEKTNTEMETKKRSLDRMSRELQDDKIRLKNDRDAYEKDM 1346 Query: 786 AVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVN--RLAVLMDHDRVVEKQLLE 843 +E +R L+R+ + L + K +E+ + + + + + +L+ + +++ E Sbjct: 1347 THLELKREELQREQEALEVMKVDILKKRNEFAKEMENVHSERQKLLLLQEQKHLKQAKAE 1406 Query: 844 IEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKAN-----RTDLAESESTKYQT 898 E K+L + ++ + E + + ++Q+ L N + DL +S + Sbjct: 1407 TEECRKQLAEMSETVTTEQNEYRKLIEELQREKEQLEISKNQIEQEKKDLQNMKSNLERK 1466 Query: 899 QLRDLESNLKRITHEHQTLIVQKKK-EIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYV 957 + DLE+ I E + + + ++ E+ EI+ +++S ++ KK ++ E + + Sbjct: 1467 EREDLENCWVEIEGEKKRMEEETRRLEMHREEIK---KVDSELQKKK---KELEDQMMDL 1520 Query: 958 TQLEAQLQEYKNNIENLNMNVEELNKMNLELIDK-HVQK---QQTQSPDYTEQYINE-IN 1012 T+ + + +E +NN+ L +E+L K N + +K ++K ++ Q + +Q +N+ Sbjct: 1521 TREKQETEEERNNLMALKNQLEDLRKENEIVKEKLTLEKSNIEEMQLKIFKQQRLNDQTR 1580 Query: 1013 KLNALLKQK-DEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVS--- 1068 + N K+ +++ Q+ ++S M+ + ++++A + +L+ ++E+++++ Sbjct: 1581 EENKKEKESLEQQRFETEQQKQMLEISTTKMMEE-KNEMADLSRELQKAKDELEKIAYKT 1639 Query: 1069 -KQLLDSKQHNEEL--QILVREQDDQIKELKETKLTF-EMNIPKTEGMIISSTIEPMSDD 1124 K+ + +Q EL QI EQ QI + K+ L E++I KT +E MS D Sbjct: 1640 NKERHEVEQMQAELHSQIQAIEQQGQIMQDKQNHLEEKELSIQKTRRQ--KEDLEKMSTD 1697 Query: 1125 ANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTE 1184 + K + E + RS + + KLN ++ + LE + +E Sbjct: 1698 IKEQNQDLMKQRDLLEQEKEDIKSELERVRSEIDHEQKKLNDYMKMIEQEKEDLEKMKSE 1757 Query: 1185 LTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLA 1244 + +E+ ++L +K++Q N E ++ + E+ + V+++ + +L KQ + Sbjct: 1758 IMKQRQQMEEERSELDNKIQQTNLEKHDIEKS-KEIVEKLMVEVEEQSKQREDLTKQEME 1816 Query: 1245 QREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEE 1304 + + D +K + E+ Q E + +L + ++ + E + + E V L K++++ + Sbjct: 1817 EEKEDLEKMKSEIMTQRQQMEEERSELDNKIKQTDLERHDIENSKEIVQKLMVKVEEQRK 1876 Query: 1305 HLRNLQEKYADVINQIEILRSEIEDEK-VAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQ 1363 +R LQ++ +++I R +I DE+ + D Q + + Sbjct: 1877 DIR-LQKE------ELDIERQKIADEQGLVVQNKAKLQNENERIKEMDEEINKQKEEDLT 1929 Query: 1364 EQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELT-HQLELKDSEIYQK--- 1419 +Q + +E+ + KS D + K +L H +E EI QK Sbjct: 1930 KQKKMEEEKEDLEKMKSEIMKQRQQMEEERSELDNKIKQTDLERHDIE-NSKEIVQKLMV 1988 Query: 1420 -THEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQK 1478 E + + +E + RQ++ + + + + ++E ++ E ET+ K Sbjct: 1989 EVEEQRKDIRLQKEELDIERQKIADEQGLVVQNKAKLQNENERIKEMDEEIKKEKETL-K 2047 Query: 1479 ESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQ-------TALENQEI 1531 E E K EE+ I E+ K+ E + L+ E K + Q + L+N+ Sbjct: 2048 EMEAHLRKEKEEMRSVIEETQRRQKEDLEKKEELDIERQKIADEQDLLIQNKSELQNENE 2107 Query: 1532 EIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAE 1588 I +N+ I + ++ K ++ + + K+ R + L+ T +L+ +AE Sbjct: 2108 RIKNINEVIKKERETLKEIKQK-EEDLPKEKEMKEDR-KSLEET-KANILEMKTKAE 2161 Score = 147 bits (357), Expect = 2e-33 Identities = 255/1411 (18%), Positives = 591/1411 (41%), Gaps = 103/1411 (7%) Query: 213 DTKQQMTKMQENFIAMEAEWKDEKQRLLK---DIESKDVRISSLEEANKLLEAARFEISL 269 D Q + E+ M+ + ++ ++ + K D+E+K +I EE K L+A EI Sbjct: 7 DFDQSRKSLDEDLKMMKLQKQEMRENISKQTEDVENKKEKIRLREEKLKQLQA---EIHK 63 Query: 270 EHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANM-TELTKKI 328 + S+ +E L + E S + E E E+ M TEL ++ Sbjct: 64 QQSETEKEKSNIERERAAIIKDVEDLQNRDAE-SLKLDREAFENEKEELKQMKTELEREA 122 Query: 329 ELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQ 388 + +E + + + + +E A + ++ + + + K K ++ Sbjct: 123 DEIEKIKLETQHERQRVEEMTADFMETMNNIKEETQNERQRLEKMT--EELKKEKESFTH 180 Query: 389 LSSETLNQDTDKKI-NKNEIAKLEMV--IQSLNKDLVDKEYVISEKDTXXXXXXXXXXGK 445 L+ +T T+KKI +K ++A ++ +Q +L + IS++ + Sbjct: 181 LAEDT---KTEKKILDKMKVANESLMADLQKEKSNLEEMRENISKQTEDSEKEKEKIRLR 237 Query: 446 DTLIAQLQLE-HQQHME-------GPSLIHVGTNTEDVNEIAKVQEQLKQEL-NDEIKDV 496 + + QLQ E H+Q E + + E V EI K++E+++ E N E Sbjct: 238 EDELEQLQAEIHKQQGEIKMEKSNNEKQMKIELEREAV-EIRKIKEEIQNERQNLEKMTE 296 Query: 497 NVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLK---LKQMQKTIDNFSKVSDS 553 +K+ E ++ +E + Q+ E++ + + + K+ ++M + +++ Sbjct: 297 ALKEEREAFENEKEVLKQMKTELEREAEIQKEREDLEKMNENITREMHEIKHQEEQMNQK 356 Query: 554 NKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRL 613 E+ +L E+ +L Q ELE+EK ++ + D + +S++ K+ M ++ ET Sbjct: 357 QDELDQLKTEIQNLQQ---ELEKEK---EIIMKDRSQLDLRQSELDKQQTNMNDIMETMK 410 Query: 614 KAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSA 673 L+ K ++ ++ ++++ +E ++KL + +++ ++ EI + E Q Sbjct: 411 NERKQLDKDKEEMEEQKQEMEKEREE-KNKLEQM-KIELEREADEISKIKEETQNKRQRL 468 Query: 674 SKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKIS 733 K A E + + + I+ E KED+ + +N + E + +EKM+ E I+ Sbjct: 469 EKMTEAFENEKEAMKQMKTDLQIQADEIVKEDLEKQKENTLAEIQKEREDVEKMN-ENIT 527 Query: 734 ELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRY 793 + +I H+E+ Q Q +D E I+N++ EL K K I + + R+ Sbjct: 528 REMHEIKHQEEQMNQKQDELDQLKTE----IQNLQQELEKEKEIIMKDRSQFDL---RQS 580 Query: 794 SLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQK 853 L+++ + ++ + + ++E + + + +EK+ + + K L K Sbjct: 581 ELDKQQTNMNDIMETMKNERKQLDKDKEE-------MEEQKQEMEKEKHDFDQSRKSLDK 633 Query: 854 KNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHE 913 +++ + Q + + ++Q L +A+ + E+ + L + LK+ E Sbjct: 634 DLKMMKLQKQVFEEEKNKLEQMKIELEREADEIRKIKEETQNERQSLEKMTEELKK-EKE 692 Query: 914 HQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQ-LEAQLQEYKNNIE 972 T + + K+++E + QI+ D + EK N+E + + + Q ++ + + Sbjct: 693 SFTHLAEVKEDLEKQKENTLAQIQKEREDLDLQKEK--SNLEEMKENISKQTEDIEKEKD 750 Query: 973 NLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKI 1032 + + +EL ++ E + KQQ+++ E + ++ +II+L++ Sbjct: 751 KIRLREDELEQLQAE-----IHKQQSETEIEKSNIERERAAIIKDVEDLQSKIISLDRDA 805 Query: 1033 NNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQI-LVREQDDQ 1091 + ++ + ++ E +L Q T+LE +E++++ + +Q EE+ + +++ Sbjct: 806 ESLKLDREAFENEKE-ELKQMKTELEREADEIEKIKLETQHERQRVEEMTADFMETMNNE 864 Query: 1092 IKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFI 1151 K+L + K+ E K E + + M ++D + +E+ + Sbjct: 865 RKQLDKNKVMIEEQ--KQE---MEKKRDDMDQSRKSLDEDLKMMKAQKESELAKLQEDIL 919 Query: 1152 QERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTEND 1211 Q++ + EQ L E E + +ET + + E +++ K E++ + + Sbjct: 920 QQQQEMDEQKQDLERERDELLEQWRLVETQKMDNENVKQLKTELLDE-KESTEKIRKQLE 978 Query: 1212 NLLSTVAELRSSISSAVDQRGFEIAELW-KQHLAQREADFQKTEHELRVQLSAFESKYEQ 1270 + + E + ++ +++ + + K+ + +++ + ++ + + +L E + E Sbjct: 979 QDKAYMEENKLNLHKELEELNLQKQGIQDKEEMVKQKIESEREIQQEKKKLQRSEEELED 1038 Query: 1271 LLDSVQSSTQEETNKI-VTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIED 1329 + ++ E+ + M+QV +++++ + N E+ ++EILR+ ++ Sbjct: 1039 KMQKIKREMIEQKKDLDQKMKQVIRKRDEMEKIRSDIANATEEINRERQELEILRNNVQS 1098 Query: 1330 EKVAFXXXXXXXXXXXXXXXXDLRTENQSY-------KQMQE-QSILNINEENAQLKKSS 1381 + F E + ++M+E I EE + + Sbjct: 1099 ARHDFELLLERTANLEDEESAATDIERRELVEAVIDKEEMKEFTDIQKYKEELQSVTEEL 1158 Query: 1382 XXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQL 1441 V D + E+ Q K +E+ E L + E + +L Sbjct: 1159 LTKKRDLDQLNSDVQDLRQTIEEINIQHGKKRAELEGIGFE----LKKGEQLLEKQKDEL 1214 Query: 1442 VEYEKRIEDLTYEKES----ELAILRLKMHENANHYETM-------QKESEIERVKLI-- 1488 E +E++ +K+S + ILR ++ ET ++E E+ R +++ Sbjct: 1215 KENGWIVEEIKNKKDSLEKINMEILRSELQRQREDLETSIQKLTHEKREMEVLRSEIVLE 1274 Query: 1489 -EELNVKITESV-SLNKQVAELNKALE---EEVAKTN-EMQTALENQEIEIVTLNDEITN 1542 ++L+ K+ + S + ++ +L+ L+ +++ KTN EM+T + + L D+ Sbjct: 1275 KKDLDQKMKQDANSESDRLKDLSMKLQMQRQDIEKTNTEMETKKRSLDRMSRELQDDKIR 1334 Query: 1543 LQNMVRASSSKIQKHVSFASDTKQGRDEQLD 1573 L+N R + K H+ + Q E L+ Sbjct: 1335 LKN-DRDAYEKDMTHLELKREELQREQEALE 1364 Score = 142 bits (343), Expect = 9e-32 Identities = 252/1327 (18%), Positives = 564/1327 (42%), Gaps = 122/1327 (9%) Query: 213 DTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEA---ARFEISL 269 D K+ K+++ +A ++ K L K++E +++ +++ ++++ + EI Sbjct: 965 DEKESTEKIRKQLEQDKAYMEENKLNLHKELEELNLQKQGIQDKEEMVKQKIESEREIQQ 1024 Query: 270 EHSKLA---QELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTE-LT 325 E KL +ELE Q ++ ++ E+E+ S +IAN TE + Sbjct: 1025 EKKKLQRSEEELEDKMQKIKREMIEQKKDLDQKMKQVIRKRDEMEKIRS-DIANATEEIN 1083 Query: 326 KKIELLEHLNCQIRQTNKELENKLA-TMGTESKAVSSPSKKGSPLISRKSGRNTASKMKS 384 ++ + LE L ++ + E L T E + ++ + L+ + + Sbjct: 1084 RERQELEILRNNVQSARHDFELLLERTANLEDEESAATDIERRELVEAVIDKEEMKEFTD 1143 Query: 385 PWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXG 444 Q E L T++ + K + LN D+ D I E + G Sbjct: 1144 --IQKYKEELQSVTEELLTKKRD------LDQLNSDVQDLRQTIEEINIQH--------G 1187 Query: 445 KDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEK 504 K A+L+ + +G L+ +++ E + E++K + D ++ +N++ L + Sbjct: 1188 KKR--AELEGIGFELKKGEQLLE--KQKDELKENGWIVEEIKNK-KDSLEKINMEILRSE 1242 Query: 505 LKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQM-QKTIDNFSKVSDSNKEI-VRLTE 562 L+ E + ++ + M ++S L+ K + QK + + SD K++ ++L Sbjct: 1243 LQRQREDLETSIQKLTHEKREMEVLRSEIVLEKKDLDQKMKQDANSESDRLKDLSMKLQM 1302 Query: 563 ELHHLSQKVAELEEEKGNLQL---HLVDYDSGRMIESDVYKK-MIEMENLAETRLKAISL 618 + + + E+E +K +L L D + D Y+K M +E E + Sbjct: 1303 QRQDIEKTNTEMETKKRSLDRMSRELQDDKIRLKNDRDAYEKDMTHLELKREELQREQEA 1362 Query: 619 LESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSV------HLEEQIDALS 672 LE K D++++ + ++ + V + + LQ + + K+ L E + ++ Sbjct: 1363 LEVMKVDILKKRNEFAKEMENVHSERQKLLLLQEQKHLKQAKAETEECRKQLAEMSETVT 1422 Query: 673 ASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQ-ENMDLTDKLEKMSAEK 731 + E +IE L+ +KEQL + +E +K+D+ N N + E DL + ++ EK Sbjct: 1423 TEQNEYRKLIEELQREKEQLEISKNQIEQEKKDLQNMKSNLERKEREDLENCWVEIEGEK 1482 Query: 732 --ISELLAKIN-HEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVM 788 + E ++ H E+ K +D+++Q++ +E+ +L++ K Sbjct: 1483 KRMEEETRRLEMHREEIK-----KVDSELQKKKKELEDQMMDLTREKQET---------- 1527 Query: 789 EDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHEN 848 E+ R +L +QL +E + + T+++ + + R+ ++ E + E Sbjct: 1528 EEERNNLMALKNQLEDLRKENEIVKEKLTLEKSNIEEMQLKIFKQQRLNDQTREENKKEK 1587 Query: 849 KELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLK 908 + L+++ ++ Q L+IS + M + N + + + A+ E K + ++ Sbjct: 1588 ESLEQQRFETEQQKQMLEISTTKMMEEKNEMADLSRELQKAKDELEKIAYKTNKERHEVE 1647 Query: 909 RITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYK 968 ++ E + I +++ + ++ + N E + +K +K + + T ++ Q Q+ Sbjct: 1648 QMQAELHSQIQAIEQQGQIMQDKQNHLEEKELSIQKTRRQKEDLE-KMSTDIKEQNQDLM 1706 Query: 969 NNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYT---EQYINEINKLNA-LLKQK--- 1021 + L E++ K LE + + +Q + DY EQ ++ K+ + ++KQ+ Sbjct: 1707 KQRDLLEQEKEDI-KSELERVRSEIDHEQKKLNDYMKMIEQEKEDLEKMKSEIMKQRQQM 1765 Query: 1022 DEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEEL 1081 +EE L+ KI + + E + + ++E ++ + ++KQ + ++ E+L Sbjct: 1766 EEERSELDNKIQQTNLEKHDIEKSKEI-VEKLMVEVEEQSKQREDLTKQ--EMEEEKEDL 1822 Query: 1082 QILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXX 1141 + + E Q ++++E + + I +T+ + IE + V Sbjct: 1823 EKMKSEIMTQRQQMEEERSELDNKIKQTD--LERHDIE---NSKEIVQKLMVKVEEQRKD 1877 Query: 1142 LKVQEEEEFIQERSVLQEQSAKLNTE--LQECYTKIIQLETLNTELTGHDVVNQEQINQL 1199 +++Q+EE I+ + + EQ + + LQ +I +++ + D+ Q+++ + Sbjct: 1878 IRLQKEELDIERQKIADEQGLVVQNKAKLQNENERIKEMDEEINKQKEEDLTKQKKMEEE 1937 Query: 1200 KSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELW--KQHLAQREADFQKTEHEL 1257 K LE++ +E + E RS + + + Q E ++ K+ + + + ++ ++ Sbjct: 1938 KEDLEKMKSEIMKQRQQMEEERSELDNKIKQTDLERHDIENSKEIVQKLMVEVEEQRKDI 1997 Query: 1258 RVQLSAFESKYEQLLDS----VQSST--QEETNKIVTM-EQVTSLQNKLQDKEEHLRNLQ 1310 R+Q + + +++ D VQ+ Q E +I M E++ + L++ E HLR + Sbjct: 1998 RLQKEELDIERQKIADEQGLVVQNKAKLQNENERIKEMDEEIKKEKETLKEMEAHLRKEK 2057 Query: 1311 EKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNI 1370 E+ VI + + + E ++K DL +N+S Q + + I NI Sbjct: 2058 EEMRSVIEETQRRQKEDLEKKEELDIERQKIADEQ-----DLLIQNKSELQNENERIKNI 2112 Query: 1371 NEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQR 1430 NE +KK + + + K +L + E+K+ +K+ E T Sbjct: 2113 NEV---IKKERET-----------LKEIKQKEEDLPKEKEMKED---RKSLEETKA---- 2151 Query: 1431 NDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEE 1490 N+ + + E E++ EKE E +++ E Q +S++ER + ++ Sbjct: 2152 -----NILEMKTKAEP--EEIKKEKEKEEEEQEMRVKVEMERKEIEQIKSQLERKEELDI 2204 Query: 1491 LNVKITE 1497 KI + Sbjct: 2205 ERQKIAD 2211 Score = 135 bits (326), Expect = 1e-29 Identities = 191/963 (19%), Positives = 431/963 (44%), Gaps = 90/963 (9%) Query: 664 LEEQIDALSASKKELALVIENLKLDKEQLYGTI----KDLENDKEDI------MNKLQNY 713 +E++ S+K L ++ +KL K+++ I +D+EN KE I + +LQ Sbjct: 1 MEKEKHDFDQSRKSLDEDLKMMKLQKQEMRENISKQTEDVENKKEKIRLREEKLKQLQAE 60 Query: 714 IQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDL-YIENIESELS 772 I + T+K EK + E+ + K + Q++ +D + E + ++ +++EL Sbjct: 61 IHKQQSETEK-EKSNIERERAAIIKDVEDLQNRDAESLKLDREAFENEKEELKQMKTELE 119 Query: 773 KYKSRICRLEESIAVMEDRRYSLERKAD---QLGSYLQEKQKAYSEYTIQEDELVNRLAV 829 + I +++ + +R+ E AD + + +E Q +EL Sbjct: 120 READEIEKIK--LETQHERQRVEEMTADFMETMNNIKEETQNERQRLEKMTEELKKEKES 177 Query: 830 L--MDHDRVVEKQLLE---IEHEN--KELQKKNQILLEENQNLQISLSDMQQHYNALVEK 882 + D EK++L+ + +E+ +LQK+ L E +N+ D ++ + + Sbjct: 178 FTHLAEDTKTEKKILDKMKVANESLMADLQKEKSNLEEMRENISKQTEDSEKEKEKIRLR 237 Query: 883 ANRTDLAESESTKYQTQLRDLESNLK---RITHEHQTLIVQK-KKEIEDLEIEFNTQIES 938 + + ++E K Q +++ +SN + +I E + + ++K K+EI++ E+ Sbjct: 238 EDELEQLQAEIHKQQGEIKMEKSNNEKQMKIELEREAVEIRKIKEEIQNERQNLEKMTEA 297 Query: 939 AIRDKKVLNEKYE--KNIEYVTQLEAQLQEYKNNIENLNMNV-EELNKMNLELIDKHVQK 995 +++ + E K ++ + EA++Q+ + ++E +N N+ E++++ KH ++ Sbjct: 298 LKEEREAFENEKEVLKQMKTELEREAEIQKEREDLEKMNENITREMHEI------KHQEE 351 Query: 996 QQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTT 1055 Q Q D +Q EI L L +K++EII ++ S + +S+L + T Sbjct: 352 QMNQKQDELDQLKTEIQNLQQEL-EKEKEIIMKDR----------SQLDLRQSELDKQQT 400 Query: 1056 KLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIIS 1115 + ++ E M+ KQL K+ EE + + ++ ++ +L++ K+ E E IS Sbjct: 401 NMNDIMETMKNERKQLDKDKEEMEEQKQEMEKEREEKNKLEQMKIELE-----READEIS 455 Query: 1116 STIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQE--QSAKLNTELQECYT 1173 E + ++ +K + + IQ +++E + K NT L E Sbjct: 456 KIKEETQNKRQRLEKMTEAFENEKEAMKQMKTDLQIQADEIVKEDLEKQKENT-LAEIQK 514 Query: 1174 KIIQLETLNTELTG--HDVVNQ-EQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQ 1230 + +E +N +T H++ +Q EQ+NQ + +L+QL TE NL + + + I Q Sbjct: 515 EREDVEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEIIMKDRSQ 574 Query: 1231 RGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQ--EETNKIVT 1288 +EL KQ D +T R QL + + E+ ++ +++ K + Sbjct: 575 FDLRQSELDKQQTNMN--DIMETMKNERKQLDKDKEEMEEQKQEMEKEKHDFDQSRKSLD 632 Query: 1289 ME-QVTSLQNKLQDKEEH-LRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXX 1346 + ++ LQ ++ ++E++ L ++ + ++I ++ E ++E+ + Sbjct: 633 KDLKMMKLQKQVFEEEKNKLEQMKIELEREADEIRKIKEETQNERQSL-EKMTEELKKEK 691 Query: 1347 XXXXDLRTENQSYKQMQEQSILNINE--ENAQLKKSSXXXXXXXXXXXXRVNDAEA---K 1401 L + ++ +E ++ I + E+ L+K + D E K Sbjct: 692 ESFTHLAEVKEDLEKQKENTLAQIQKEREDLDLQKEKSNLEEMKENISKQTEDIEKEKDK 751 Query: 1402 VLELTHQLELKDSEIYQKTHEYTITLTQRNDE-------FENVRQQLVEYEKRIEDLTYE 1454 + +LE +EI+++ E I + E E+++ +++ ++ E L + Sbjct: 752 IRLREDELEQLQAEIHKQQSETEIEKSNIERERAAIIKDVEDLQSKIISLDRDAESLKLD 811 Query: 1455 KES------ELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAEL 1508 +E+ EL ++ ++ A+ E ++ E++ ER + +EE+ E+++ ++ + Sbjct: 812 REAFENEKEELKQMKTELEREADEIEKIKLETQHERQR-VEEMTADFMETMNNERKQLDK 870 Query: 1509 NKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGR 1568 NK + EE + EM+ ++ + +L++++ ++ + +K+Q+ + +Q Sbjct: 871 NKVMIEE--QKQEMEKKRDDMDQSRKSLDEDLKMMKAQKESELAKLQEDI---LQQQQEM 925 Query: 1569 DEQ 1571 DEQ Sbjct: 926 DEQ 928 Score = 107 bits (256), Expect = 3e-21 Identities = 169/885 (19%), Positives = 391/885 (44%), Gaps = 87/885 (9%) Query: 215 KQQMTKMQENFIAMEAEWKDEKQRLLKDIE---SKDVRISSLEEANKLLEAARFEISLEH 271 ++++ + QE M+ + ++ K++E S+ ++ L+E K L+ A+ E Sbjct: 1353 REELQREQEALEVMKVDILKKRNEFAKEMENVHSERQKLLLLQE-QKHLKQAKAETEECR 1411 Query: 272 SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELL 331 +LA+ E L ++ + + +EK L+ K+ E L Sbjct: 1412 KQLAEMSETVTTEQNEYRKLIEELQREKEQLEISKNQIEQEKKDLQNMKSNLERKEREDL 1471 Query: 332 EHLNCQIRQTNKELEN---KLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQ 388 E+ +I K +E +L E K V S +K + + T K ++ + Sbjct: 1472 ENCWVEIEGEKKRMEEETRRLEMHREEIKKVDSELQKKKKELEDQMMDLTREKQETEEER 1531 Query: 389 LSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTL 448 + L + +NEI K ++ ++ N + + + + ++ K++L Sbjct: 1532 NNLMALKNQLEDLRKENEIVKEKLTLEKSNIEEMQLK-IFKQQRLNDQTREENKKEKESL 1590 Query: 449 IAQLQLEHQQHMEGPSLIHVGTNT--EDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLK 506 Q + E +Q + ++ + T E+ NE+A + +L Q+ DE++ + K E+ Sbjct: 1591 -EQQRFETEQQKQ---MLEISTTKMMEEKNEMADLSREL-QKAKDELEKIAYKTNKER-H 1644 Query: 507 SAEEQITQLNDEIDAANKN--MIKVKSNH----KLKLKQMQKTIDNFSKVSDSNKEIVR- 559 E+ +L+ +I A + +++ K NH +L +++ ++ ++ K+S KE + Sbjct: 1645 EVEQMQAELHSQIQAIEQQGQIMQDKQNHLEEKELSIQKTRRQKEDLEKMSTDIKEQNQD 1704 Query: 560 LTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIE-----MENLAETRLK 614 L ++ L Q+ +++ E ++ +D++ ++ + Y KMIE +E + +K Sbjct: 1705 LMKQRDLLEQEKEDIKSELERVRSE-IDHEQKKLND---YMKMIEQEKEDLEKMKSEIMK 1760 Query: 615 AISLLESQKFDL---VQELHILQ---QKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQI 668 +E ++ +L +Q+ ++ + +K E+ +KL + QS Q ++ +EE+ Sbjct: 1761 QRQQMEEERSELDNKIQQTNLEKHDIEKSKEIVEKLMVEVEEQSKQR-EDLTKQEMEEEK 1819 Query: 669 DALSASKKELALVIENLKLDKEQLYGTIK-------DLENDKEDIMNKLQNYIQENMDLT 721 + L K E+ + ++ ++ +L IK D+EN KE + + ++ D+ Sbjct: 1820 EDLEKMKSEIMTQRQQMEEERSELDNKIKQTDLERHDIENSKEIVQKLMVKVEEQRKDIR 1879 Query: 722 DKLEKMSAEK-----------------------ISELLAKINHEEQSKIQTQFGIDAKIQ 758 + E++ E+ I E+ +IN +++ + Q K++ Sbjct: 1880 LQKEELDIERQKIADEQGLVVQNKAKLQNENERIKEMDEEINKQKEEDLTKQ----KKME 1935 Query: 759 ERDLYIENIESELSKYKSRI----CRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYS 814 E +E ++SE+ K + ++ L+ I + R+ +E + + + E ++ Sbjct: 1936 EEKEDLEKMKSEIMKQRQQMEEERSELDNKIKQTDLERHDIENSKEIVQKLMVEVEEQRK 1995 Query: 815 EYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQ 874 + +Q++EL + D +V + ++++EN+ +++ ++ + +E + L+ + +++ Sbjct: 1996 DIRLQKEELDIERQKIADEQGLVVQNKAKLQNENERIKEMDEEIKKEKETLKEMEAHLRK 2055 Query: 875 HYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNT 934 + T + E + + +L D+E ++I E Q L++Q K E+++ Sbjct: 2056 EKEEMRSVIEETQRRQKEDLEKKEEL-DIER--QKIADE-QDLLIQNKSELQNENERIKN 2111 Query: 935 QIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEEL-NKMNLELIDKHV 993 E ++++ L E +K E E +++E + ++E N+ E+ K E I K Sbjct: 2112 INEVIKKERETLKEIKQK--EEDLPKEKEMKEDRKSLEETKANILEMKTKAEPEEIKKEK 2169 Query: 994 QKQQTQSP--DYTEQYINEINKLNALLKQKDEEIIALNQKINNAQ 1036 +K++ + E EI ++ + L++K EE+ QKI + Q Sbjct: 2170 EKEEEEQEMRVKVEMERKEIEQIKSQLERK-EELDIERQKIADEQ 2213 >UniRef50_UPI00006CD140 Cluster: Viral A-type inclusion protein repeat containing protein; n=1; Tetrahymena thermophila SB210|Rep: Viral A-type inclusion protein repeat containing protein - Tetrahymena thermophila SB210 Length = 2937 Score = 170 bits (414), Expect = 2e-40 Identities = 266/1391 (19%), Positives = 590/1391 (42%), Gaps = 93/1391 (6%) Query: 213 DTKQQMTKMQENFIAMEAEWKDEKQRLLKDIES----KDVRISSLEEANKLLEAARFEIS 268 + K+Q K +E +A + E+ EK + D E K+ + SL E K E + Sbjct: 864 EQKEQHVKEREETLAQQIEFLKEKDIYVNDREQELLDKERELESLFEEQKEKEKYLENLI 923 Query: 269 LEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKI 328 E ++ + LEQ L +Q EK ++ E+ + N E K + Sbjct: 924 NEQNQKLKLLEQQSINQQSEDLK---LLEQQFINEQNEKLKLLEQQLINEQN--EKLKNL 978 Query: 329 ELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQ 388 E E L + + K LE +L + KA+ K+ ++ + ++ Q Sbjct: 979 E--EKLVNEQNEKLKLLEQQLDEHQAKEKALEQLLKEND---GKQKELDLLISQQAEKEQ 1033 Query: 389 LSSETLNQDTDKKINKNEIA-KLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDT 447 + + + Q ++ +I + + Q L + ++ + + + D Sbjct: 1034 VLQQLMEQQKQREYEFEQIVNEQKQKEQELEQLFSEQSKIKHQLEQQLAQQIEKEQELDQ 1093 Query: 448 LIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKS 507 LI + Q +Q I + T ++ + VQE ++ E D N ++L +LK Sbjct: 1094 LINEAQSRNQATFTEEQEIVLTTPKKEERQERTVQEGRNEDFT-EGNDENEEELELRLKK 1152 Query: 508 AEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHL 567 E + Q +I +A KN K K+ ++K + N+ + K + + L Sbjct: 1153 EVEDLQQ-QLQI-SAQKNQESAK-----KIIDLEKAVQNYQMIERDEKNFEEIFRQNKKL 1205 Query: 568 SQKVAELEEEKGNLQLHLVDYDSG-RMIESDVYKKMIEMENLAETRLKAISLLESQKFDL 626 K+ E E + L + + S + + +++ E + +E+ K++ Sbjct: 1206 EDKIKSYEMEYSARKNQLEHQEQTIAKLHSQLVQADADLQKYIEDKRLLNDKIEALKYEK 1265 Query: 627 VQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLK 686 +E+ L+Q+ D + + ++S+ + E ++ I+ LS ++ I+NL Sbjct: 1266 EEEIKRLKQENDIEKMSRSQSKLMESESIAFESIVGDYKDTINMLSNKCEDYETQIQNLT 1325 Query: 687 LDKEQLYGTIKDLEND----KEDIMNK---LQNYIQENMDLTDKLE--KMSAEKISELLA 737 L + K+++++ +E++ NK +Q Q+ +L + K A+K+ + L Sbjct: 1326 KQNNVLVNSFKEIKSNLTSYQEELDNKEEFIQKQSQDMFELQKSVNQYKQMAKKLEDQLK 1385 Query: 738 KINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLER 797 ++++ Q + T + ++++ ++ +E ++ I L E I+++E + Sbjct: 1386 DLSNKSQEESST---LQYELEKNNILLEQKNKDVQAKNQEIQSLYEKISLIEKSNL---Q 1439 Query: 798 KADQLGSYLQEKQKAYSEYTIQEDELVNRLAV-LMDHDRVVEKQLLEIEHENKELQKKNQ 856 K + L +QE+Q E + ++LV++ + + +V+++Q E ++LQ+ +Q Sbjct: 1440 KLEDLNLVIQEEQNQRKEIQTELEQLVDKYNQDVQELQKVMDQQQEEFTQIQQQLQESSQ 1499 Query: 857 ILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQT 916 +EN NL+ + ++Q L +K + E + L+ +E++LK+ HE Sbjct: 1500 NQQKENLNLKEQMEHLKQQ---LDQKNAEIVSKQEELLNLEDMLQKIENDLKQQKHEFD- 1555 Query: 917 LIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYK--NNIENL 974 L +QK+++ + ++ +I +++ L ++ +++ +Q + ++ + K N + L Sbjct: 1556 LQIQKQEDSNNQHVDQLQKIIDEKQEEISLLQQNQQDSSLRSQEDLKILKIKLDNLVSEL 1615 Query: 975 NMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINN 1034 N E+LN+M+ EL K Q + T+ ++Y IN+L +KQ D L + Sbjct: 1616 NNANEQLNEMDKELQFKDEQLKLTE-----KEYQMNINQLQ--VKQND-----LQDQKKQ 1663 Query: 1035 AQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKE 1094 + Y ++ Q ++ +E++Q + + LL S + E+ + + Q K+ Sbjct: 1664 LEEMLQEQEERYSQEITQLQNIIDQQQEDLQGLQQNLLGSSKIQEDKNKALTNELQQAKQ 1723 Query: 1095 LKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQER 1154 E K+ ++ + + S+ N K ++ +E IQ Sbjct: 1724 EIE-KMNHQLQAQHKDLEKAYQQFDD-SEKQNQQKLKSAEVKLQDLEAKYKDLQESIQ-- 1779 Query: 1155 SVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLL 1214 + QE+ +K ELQ II+ + L ++ + N L K++ L+ +N + Sbjct: 1780 -IEQEKYSKDIEELQN----IIETQQQEINLMEQNMTKLK--NDLDRKVKDLDVKNIEIQ 1832 Query: 1215 STVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDS 1274 + ++L S+ + +D+ + ++ ++++ + + L +L E KY + + Sbjct: 1833 AKDSDLESAYAQ-IDKIDIQYQHKLNEYESKQQ-ELANNNNHLEGKLIELEDKYNKDVSE 1890 Query: 1275 VQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQ--IEILRSEIEDEKV 1332 +Q +++ + +EQ Q ++ +LR EK + +++ EIL E + + Sbjct: 1891 LQKVIEQQQQDLNNLEQELYNQGSQNEETSNLRVELEKVSIQLDERNSEILIKNKELDSM 1950 Query: 1333 AFXXXXXXXXXXXXXXXXDLRTEN-QSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXX 1391 +++ ++ Q K+ +Q +L ++ +N+Q Sbjct: 1951 YEQIDKIERQYQQKLREQEIKIQDLQKLKKEYDQQLLELDNKNSQ---DIADLKNIIEQQ 2007 Query: 1392 XXRVNDAEAKVLELT-HQLELKDS--EIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRI 1448 +N+ + + E T HQ E + E+ +K + L Q+N E + + +Q+ + EK+ Sbjct: 2008 QEDLNNMQKDLFENTKHQEENNNLRFELERKNIQLNSDLIQKNKELDQLHEQINKIEKQN 2067 Query: 1449 EDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAE- 1507 + ++E LK+ + N +KE +++ ++ E+ N ITE + +Q E Sbjct: 2068 QQKLRDQE-------LKLQDLQNQ----KKEFDLKLMEQEEKNNQYITELQKIIEQQQED 2116 Query: 1508 LNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQG 1567 LNK +E+ + + N Q + N EI +E+ N + +++ + ++ Sbjct: 2117 LNK-MEQCLYENNGSQDEINNLRSEIEKQQNELDEKSNEINQKEKELEDMFQQMQEVERQ 2175 Query: 1568 RDEQLDNTMNK 1578 ++L+ T +K Sbjct: 2176 YQDKLNETESK 2186 Score = 167 bits (407), Expect = 2e-39 Identities = 292/1510 (19%), Positives = 644/1510 (42%), Gaps = 142/1510 (9%) Query: 164 KMKIMETTILDLQ-EKI-NEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKM 221 K+K++E +++ Q EK+ N +++++ +N+ + K+ K Sbjct: 959 KLKLLEQQLINEQNEKLKNLEEKLVNEQNEKLKLLEQQLDEHQAKEKALEQLLKENDGKQ 1018 Query: 222 QEN--FIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELE 279 +E I+ +AE + Q+L++ + ++ + K E ++ E SK+ +LE Sbjct: 1019 KELDLLISQQAEKEQVLQQLMEQQKQREYEFEQIVNEQKQKEQELEQLFSEQSKIKHQLE 1078 Query: 280 QXXXXXXXXXXXXXXLA-------------KQSIEPSCEEKTEIEEKGSLEIANMTELTK 326 Q L +Q I + +K E +E+ E N Sbjct: 1079 QQLAQQIEKEQELDQLINEAQSRNQATFTEEQEIVLTTPKKEERQERTVQEGRNEDFTEG 1138 Query: 327 KIELLEHLNCQIRQTNKELENKL---ATMGTES--KAVSSPSKKGSPLISRKSGRNTASK 381 E E L ++++ ++L+ +L A ES K + + + + +N Sbjct: 1139 NDENEEELELRLKKEVEDLQQQLQISAQKNQESAKKIIDLEKAVQNYQMIERDEKNFEEI 1198 Query: 382 MKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLV----DKEYVISEKDTXXXX 437 + +L + + + + KN++ E I L+ LV D + I +K Sbjct: 1199 FRQN-KKLEDKIKSYEMEYSARKNQLEHQEQTIAKLHSQLVQADADLQKYIEDKRLLNDK 1257 Query: 438 XXXXXXGKDTLIAQLQLEHQ---------QHMEGPSLIH---VGTNTEDVNEIAKVQEQL 485 K+ I +L+ E+ + ME S+ VG + +N ++ E Sbjct: 1258 IEALKYEKEEEIKRLKQENDIEKMSRSQSKLMESESIAFESIVGDYKDTINMLSNKCEDY 1317 Query: 486 KQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTID 545 + ++ + K NV L+ K + +T +E+D NK K + + ++QK+++ Sbjct: 1318 ETQIQNLTKQNNV--LVNSFKEIKSNLTSYQEELD--NKEEFIQKQSQDMF--ELQKSVN 1371 Query: 546 NFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYD---SGRMIESDVYKKM 602 + +++ ++ ++ + E EK N+ L + D + I+S +Y+K+ Sbjct: 1372 QYKQMAKKLEDQLKDLSNKSQEESSTLQYELEKNNILLEQKNKDVQAKNQEIQS-LYEKI 1430 Query: 603 IEMENLAETRLKAISLL----ESQKFDLVQELHILQQKY-----------DEVEDKLADI 647 +E +L+ ++L+ ++Q+ ++ EL L KY D+ +++ I Sbjct: 1431 SLIEKSNLQKLEDLNLVIQEEQNQRKEIQTELEQLVDKYNQDVQELQKVMDQQQEEFTQI 1490 Query: 648 SQ-LQSDQVCSEIKSVHLEEQIDALSAS--KKELALVIENLKL-DKEQLYGTIK-DLEND 702 Q LQ + ++++L+EQ++ L +K +V + +L + E + I+ DL+ Sbjct: 1491 QQQLQESSQNQQKENLNLKEQMEHLKQQLDQKNAEIVSKQEELLNLEDMLQKIENDLKQQ 1550 Query: 703 KEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDL 762 K + ++Q N D+L+K+ EK E+ +++ S +++Q D KI + + Sbjct: 1551 KHEFDLQIQKQEDSNNQHVDQLQKIIDEKQEEISLLQQNQQDSSLRSQE--DLKILK--I 1606 Query: 763 YIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLG-SYLQEKQKAYSEYTIQED 821 ++N+ SEL+ ++ +++ + +D + L K Q+ + LQ KQ + Q + Sbjct: 1607 KLDNLVSELNNANEQLNEMDKELQ-FKDEQLKLTEKEYQMNINQLQVKQNDLQDQKKQLE 1665 Query: 822 ELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVE 881 E+ L + + +++ ++++ + Q+ Q L QNL + S +Q+ N + Sbjct: 1666 EM------LQEQEERYSQEITQLQNIIDQQQEDLQGL---QQNL-LGSSKIQEDKNKAL- 1714 Query: 882 KANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIR 941 N A+ E K QL+ +L++ + Q +++++ E++ +E+ + Sbjct: 1715 -TNELQQAKQEIEKMNHQLQAQHKDLEKAYQQFDDSEKQNQQKLKSAEVKLQ-DLEAKYK 1772 Query: 942 DK----KVLNEKYEKNIEYVTQ-LEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQ 996 D ++ EKY K+IE + +E Q QE +N+ +L++ +L K+++ Q Sbjct: 1773 DLQESIQIEQEKYSKDIEELQNIIETQQQEINLMEQNMTKLKNDLDRKVKDLDVKNIEIQ 1832 Query: 997 QTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKI----NNAQVSYMSMVSDYESKLAQ 1052 S D Y +I+K++ + K E + Q++ N+ + + + Y +++ Sbjct: 1833 AKDS-DLESAYA-QIDKIDIQYQHKLNEYESKQQELANNNNHLEGKLIELEDKYNKDVSE 1890 Query: 1053 FTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGM 1112 +E ++++ + ++L + NEE L E + K++ +++ +E + Sbjct: 1891 LQKVIEQQQQDLNNLEQELYNQGSQNEETSNLRVELE---------KVSIQLDERNSEIL 1941 Query: 1113 IISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQE----EEEFIQERSVLQEQSAKLNTEL 1168 I + ++ M + + ++ +K+Q+ ++E+ Q+ L ++++ +L Sbjct: 1942 IKNKELDSMYEQIDKIE-RQYQQKLREQEIKIQDLQKLKKEYDQQLLELDNKNSQDIADL 2000 Query: 1169 QECYTKIIQLETLNTELTG--HDVVNQEQINQLKSKLEQLNTE-NDNLLSTVAELRSSIS 1225 + + Q E LN + +QE+ N L+ +LE+ N + N +L+ EL Sbjct: 2001 KNIIEQ--QQEDLNNMQKDLFENTKHQEENNNLRFELERKNIQLNSDLIQKNKELDQLHE 2058 Query: 1226 SAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNK 1285 +L Q L ++ QK E +L+ L E K Q + +Q +++ Sbjct: 2059 QINKIEKQNQQKLRDQELKLQDLQNQKKEFDLK--LMEQEEKNNQYITELQKIIEQQQED 2116 Query: 1286 IVTMEQVTSLQNKLQDKEEHLRNLQEKYADVI----NQIEILRSEIED---EKVAFXXXX 1338 + MEQ N QD+ +LR+ EK + + N+I E+ED + Sbjct: 2117 LNKMEQCLYENNGSQDEINNLRSEIEKQQNELDEKSNEINQKEKELEDMFQQMQEVERQY 2176 Query: 1339 XXXXXXXXXXXXDLRTENQ----SYKQMQEQSILNINE------ENAQLKKSSXXXXXXX 1388 +L+ +N +++ +++S +I+E + ++ Sbjct: 2177 QDKLNETESKLKELQNQNNEIIGKFEESEQKSNFHISELQKIIDQQQEMIGRMDQDLFDT 2236 Query: 1389 XXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRI 1448 N ++ T QLE +++EI K E Q + +Q+L ++E + Sbjct: 2237 SRQQEENNSLRMELERKTLQLEQRNAEILSKNKELESKYDQLDKIERQYQQKLRDFELKQ 2296 Query: 1449 EDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAEL 1508 +DL +K+ EL + L+ EN E +Q+E E+++ +L L+ + E LN ++ Sbjct: 2297 QDLQNQKK-ELELRLLEQEENGGSLEKLQREFEMQKKELENILDKQQIEIEELNDKLIRQ 2355 Query: 1509 NKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQ-KHVSFASDTKQG 1567 + E ++A+ N +++ E++ T ++ LQ +R + ++ K+ D K Sbjct: 2356 REDYEYQLAQAN---NRIQSIELDHKTEIKKLMKLQEELRLQNRDMENKYERLKEDHKNI 2412 Query: 1568 RDEQLDNTMN 1577 ++ +N+ + Sbjct: 2413 QNSSFNNSFD 2422 Score = 162 bits (394), Expect = 6e-38 Identities = 232/1212 (19%), Positives = 531/1212 (43%), Gaps = 83/1212 (6%) Query: 445 KDTL--IAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNV-KDL 501 KD L I + E QQ ++ + T +++ E+ + LK N D + KD Sbjct: 669 KDILNEIKTFKQEKQQKDPEEIVMRLSTLLQEL-EVQNLNNSLKLSQNQIPNDSQIEKDF 727 Query: 502 IEKLKSA--EEQITQLNDEIDAANKNMI-KVKSNHKLKLKQMQKTIDNFSKVSDSNKEIV 558 +K++++ +E + + + A K+ + + K+ ++ QK + +K +E++ Sbjct: 728 EQKIQASLQKESLKKEEKQNSEAQKDEVTEFNQEDKIDKEEFQKEKEIITK---EKEELI 784 Query: 559 RLTEELHH----LSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLK 614 +L E+L +++ E+E++K L+L + + M + K++ E++N + + + Sbjct: 785 QLKEDLRKQKEDFNKQKQEVEKQKSELELKAENLNLISMQFEEREKELEEVQNTLQQQQE 844 Query: 615 AISLLESQKFDLVQELHILQQKYDEVEDKLADISQ----LQSDQVCSEIKSVHL---EEQ 667 +S Q + +L +L+QK V+++ ++Q L+ + + L E + Sbjct: 845 ELSQKRKQYEQIQDKLELLEQKEQHVKEREETLAQQIEFLKEKDIYVNDREQELLDKERE 904 Query: 668 IDALSASKKELALVIENLKLDKEQLYGTIKD--LENDKEDIMNKLQNYIQENMDLTDKLE 725 +++L +KE +ENL ++ Q ++ + ED+ Q +I E + LE Sbjct: 905 LESLFEEQKEKEKYLENLINEQNQKLKLLEQQSINQQSEDLKLLEQQFINEQNEKLKLLE 964 Query: 726 KM----SAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRL 781 + EK+ L K+ +E+ K++ ++ ++ E + +E L + + L Sbjct: 965 QQLINEQNEKLKNLEEKLVNEQNEKLKL---LEQQLDEHQAKEKALEQLLKENDGKQKEL 1021 Query: 782 EESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQL 841 + I+ ++ L++ +Q E ++ +E +E EL + +E+QL Sbjct: 1022 DLLISQQAEKEQVLQQLMEQQKQREYEFEQIVNEQKQKEQELEQLFSEQSKIKHQLEQQL 1081 Query: 842 LE-IEHENK------ELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAE-SES 893 + IE E + E Q +NQ E Q + ++ ++ V++ D E ++ Sbjct: 1082 AQQIEKEQELDQLINEAQSRNQATFTEEQEIVLTTPKKEERQERTVQEGRNEDFTEGNDE 1141 Query: 894 TKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIES---AIRDKKVLNEKY 950 + + +LR L+ ++ + + Q + QK +E I+ +++ RD+K E + Sbjct: 1142 NEEELELR-LKKEVEDLQQQLQ-ISAQKNQESAKKIIDLEKAVQNYQMIERDEKNFEEIF 1199 Query: 951 EKNIEYVTQLEAQLQEY---KNNIENLNMNVEELNKMNLEL---IDKHVQKQQTQSPDYT 1004 +N + ++++ EY KN +E+ + +L+ ++ + K+++ ++ + Sbjct: 1200 RQNKKLEDKIKSYEMEYSARKNQLEHQEQTIAKLHSQLVQADADLQKYIEDKRLLNDKIE 1259 Query: 1005 EQYINEINKLNALLKQKDEEIIALNQK--INNAQVSYMSMVSDYESKLAQFTTKLENMEE 1062 + ++ L ++ D E ++ +Q + + +++ S+V DY+ + + K E+ E Sbjct: 1260 ALKYEKEEEIKRLKQENDIEKMSRSQSKLMESESIAFESIVGDYKDTINMLSNKCEDYET 1319 Query: 1063 EMQRVSKQ---LLDS-KQHNEELQILVREQDDQIKEL-KETKLTFEMNIPKTEGMIISST 1117 ++Q ++KQ L++S K+ L E D++ + + K+++ FE+ + ++ Sbjct: 1320 QIQNLTKQNNVLVNSFKEIKSNLTSYQEELDNKEEFIQKQSQDMFELQKSVNQYKQMAKK 1379 Query: 1118 IEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQ 1177 +E D +N L+ + E+ I ++ AK N E+Q Y KI Sbjct: 1380 LEDQLKDLSN------KSQEESSTLQYELEKNNILLEQKNKDVQAK-NQEIQSLYEKISL 1432 Query: 1178 LETLNTE-LTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIA 1236 +E N + L ++V QE+ NQ K ++ TE + L+ + + +DQ+ E Sbjct: 1433 IEKSNLQKLEDLNLVIQEEQNQRK----EIQTELEQLVDKYNQDVQELQKVMDQQQEEFT 1488 Query: 1237 ELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQ 1296 ++ +Q L + + QK L+ Q+ + + +Q + S QEE + M Q ++ Sbjct: 1489 QI-QQQLQESSQNQQKENLNLKEQMEHLKQQLDQKNAEIVSK-QEELLNLEDMLQ--KIE 1544 Query: 1297 NKLQDKEEHLRNLQ-EKYADVINQ-IEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRT 1354 N L+ +++H +LQ +K D NQ ++ L+ I++++ DL+ Sbjct: 1545 NDLK-QQKHEFDLQIQKQEDSNNQHVDQLQKIIDEKQEEISLLQQNQQDSSLRSQEDLKI 1603 Query: 1355 ENQSYKQM-QEQSILN--INEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLEL 1411 + E + N +NE + +L+ +N + K +L Q + Sbjct: 1604 LKIKLDNLVSELNNANEQLNEMDKELQFKDEQLKLTEKEYQMNINQLQVKQNDLQDQKKQ 1663 Query: 1412 KDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENAN 1471 + + ++ Y+ +TQ + + ++ L ++ + + +E + L ++ + Sbjct: 1664 LEEMLQEQEERYSQEITQLQNIIDQQQEDLQGLQQNLLGSSKIQEDKNKALTNELQQAKQ 1723 Query: 1472 HYETMQKESEIERVKLIEELNVKITESVSLNKQ-VAELNKALEEEVAKTNEMQTALENQE 1530 E M + + + K +E+ + +S N+Q + L++ AK ++Q E+ + Sbjct: 1724 EIEKMNHQLQAQH-KDLEKAYQQFDDSEKQNQQKLKSAEVKLQDLEAKYKDLQ---ESIQ 1779 Query: 1531 IEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELD 1590 IE + +I LQN++ +I + K D ++ + K + ++L+ Sbjct: 1780 IEQEKYSKDIEELQNIIETQQQEINLMEQNMTKLKNDLDRKVKDLDVKNIEIQAKDSDLE 1839 Query: 1591 LAMYMLHQRDVR 1602 A + + D++ Sbjct: 1840 SAYAQIDKIDIQ 1851 Score = 152 bits (369), Expect = 7e-35 Identities = 218/1178 (18%), Positives = 495/1178 (42%), Gaps = 75/1178 (6%) Query: 174 DLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWK 233 D+++ + +++E+++ A ED + Q+ + + + +K Sbjct: 1277 DIEKMSRSQSKLMESESIAFESIVGDYKDTINMLSNKCEDYETQIQNLTKQNNVLVNSFK 1336 Query: 234 DEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXX 293 + K L E D + +++ ++ + + ++ ++ ++A++LE Sbjct: 1337 EIKSNLTSYQEELDNKEEFIQKQSQDMFELQKSVN-QYKQMAKKLEDQLKDLSNKSQEES 1395 Query: 294 XLAKQSIEPS---CEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQ-IRQTN---KELE 346 + +E + E+K + + + EI ++ E KI L+E N Q + N +E + Sbjct: 1396 STLQYELEKNNILLEQKNKDVQAKNQEIQSLYE---KISLIEKSNLQKLEDLNLVIQEEQ 1452 Query: 347 NKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNE 406 N+ + TE + + + + + + + QL + NQ + K + Sbjct: 1453 NQRKEIQTELEQLVDKYNQDVQELQKVMDQQQ-EEFTQIQQQLQESSQNQQKENLNLKEQ 1511 Query: 407 IAKLEMVIQSLNKDLVDK-EYVISEKDTXXXXXXXXXXGKDTLIAQLQLE---HQQHMEG 462 + L+ + N ++V K E +++ +D K Q+Q + + QH++ Sbjct: 1512 MEHLKQQLDQKNAEIVSKQEELLNLEDMLQKIENDLKQQKHEFDLQIQKQEDSNNQHVDQ 1571 Query: 463 PSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVK--DLIEKLKSAEEQITQLNDEID 520 I + E+++ + + Q+ +++K + +K +L+ +L +A EQ+ +++ E+ Sbjct: 1572 LQKI-IDEKQEEISLLQQNQQDSSLRSQEDLKILKIKLDNLVSELNNANEQLNEMDKELQ 1630 Query: 521 AANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIV-----RLTEELHHLSQKVAELE 575 ++ + + +++ + Q+Q ++ +E++ R ++E+ L + + + Sbjct: 1631 FKDEQLKLTEKEYQMNINQLQVKQNDLQDQKKQLEEMLQEQEERYSQEITQLQNIIDQQQ 1690 Query: 576 EEKGNLQLHL-----VDYDSGRMIESDVYKKMIEMENLAETRLKAISLLES--QKFDLVQ 628 E+ LQ +L + D + + +++ + E+E + LE Q+FD + Sbjct: 1691 EDLQGLQQNLLGSSKIQEDKNKALTNELQQAKQEIEKMNHQLQAQHKDLEKAYQQFDDSE 1750 Query: 629 ELHILQQKYDEVEDKLADISQLQSD-----QVCSEIKSVHLEEQIDALSASKKELALVIE 683 + + QQK E KL D+ D Q+ E S +EE + + ++E+ L+ + Sbjct: 1751 KQN--QQKLKSAEVKLQDLEAKYKDLQESIQIEQEKYSKDIEELQNIIETQQQEINLMEQ 1808 Query: 684 NLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKI---- 739 N+ K L +KDL+ +I K + ++ DK++ K++E +K Sbjct: 1809 NMTKLKNDLDRKVKDLDVKNIEIQAK-DSDLESAYAQIDKIDIQYQHKLNEYESKQQELA 1867 Query: 740 ---NHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLE 796 NH E I+ + + + E IE + +L+ + + + R LE Sbjct: 1868 NNNNHLEGKLIELEDKYNKDVSELQKVIEQQQQDLNNLEQELYNQGSQNEETSNLRVELE 1927 Query: 797 RKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKK-- 854 + + QL + SE I+ EL + + +R +++L E E + ++LQK Sbjct: 1928 KVSIQL-------DERNSEILIKNKELDSMYEQIDKIERQYQQKLREQEIKIQDLQKLKK 1980 Query: 855 --NQILLE-ENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRIT 911 +Q LLE +N+N Q ++D++ E N E+TK+Q + +L L+R Sbjct: 1981 EYDQQLLELDNKNSQ-DIADLKNIIEQQQEDLNNMQKDLFENTKHQEENNNLRFELERKN 2039 Query: 912 HEHQTLIVQKKKEIEDLEIEFNT---QIESAIRDKKVL-----NEKYEKNIEYVTQLEAQ 963 + + ++QK KE++ L + N Q + +RD+++ N+K E +++ + Q E Sbjct: 2040 IQLNSDLIQKNKELDQLHEQINKIEKQNQQKLRDQELKLQDLQNQKKEFDLKLMEQEEKN 2099 Query: 964 LQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQS-PDYTEQYINEINKLNALLKQKD 1022 Q + + E+LNKM L + + + + + E+ NE+++ + + QK+ Sbjct: 2100 NQYITELQKIIEQQQEDLNKMEQCLYENNGSQDEINNLRSEIEKQQNELDEKSNEINQKE 2159 Query: 1023 EEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEM-QRVSKQLLDSKQHNEEL 1081 +E+ + Q++ + Y +++ ESKL + L+N E+ + + S H EL Sbjct: 2160 KELEDMFQQMQEVERQYQDKLNETESKLKE----LQNQNNEIIGKFEESEQKSNFHISEL 2215 Query: 1082 QILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXX 1141 Q ++ +Q + I + + + + + + + + N + Sbjct: 2216 QKIIDQQQEMIGRMDQDLFDTSRQQEENNSLRMELERKTLQLEQRNAEILSKNKELESKY 2275 Query: 1142 LKVQE-EEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLK 1200 ++ + E ++ Q+ + + L + +E ++++ E L + Q +L+ Sbjct: 2276 DQLDKIERQYQQKLRDFELKQQDLQNQKKELELRLLEQEENGGSLEKLQREFEMQKKELE 2335 Query: 1201 SKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQ 1260 + L++ E + L + R + Q I + H + + K + ELR+Q Sbjct: 2336 NILDKQQIEIEELNDKLIRQREDYEYQLAQANNRIQSIELDHKTEIKK-LMKLQEELRLQ 2394 Query: 1261 LSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNK 1298 E+KYE+L + ++ N NK Sbjct: 2395 NRDMENKYERLKEDHKNIQNSSFNNSFDANNKLGTPNK 2432 Score = 152 bits (368), Expect = 9e-35 Identities = 244/1268 (19%), Positives = 539/1268 (42%), Gaps = 98/1268 (7%) Query: 380 SKMKSPWSQLSSETLNQDTDKKINK-NEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXX 438 S+++ + Q +L +++ KK K N A+ + V + +D +DKE EK+ Sbjct: 721 SQIEKDFEQKIQASLQKESLKKEEKQNSEAQKDEVTEFNQEDKIDKEEFQKEKEIITKEK 780 Query: 439 XXXXXGKDTLIAQLQLEHQQHME-GPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVN 497 K+ L Q + ++Q E + E++N I+ E+ ++EL +E+++ Sbjct: 781 EELIQLKEDLRKQKEDFNKQKQEVEKQKSELELKAENLNLISMQFEEREKEL-EEVQNT- 838 Query: 498 VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEI 557 ++ E+L +Q Q+ D+++ + VK + +Q++ + V+D +E+ Sbjct: 839 LQQQQEELSQKRKQYEQIQDKLELLEQKEQHVKEREETLAQQIEFLKEKDIYVNDREQEL 898 Query: 558 VRLTEELHHLSQKVAELEEEKGNL------QLHLVDYDSGRMIESDVYKKMIEMENLAET 611 + EL L ++ E E+ NL +L L++ S D+ K++E + + E Sbjct: 899 LDKERELESLFEEQKEKEKYLENLINEQNQKLKLLEQQSINQQSEDL--KLLEQQFINEQ 956 Query: 612 RLKAISLLESQKFDLVQE-LHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDA 670 K + LLE Q + E L L++K +++ + + Q D+ + K LE+ + Sbjct: 957 NEK-LKLLEQQLINEQNEKLKNLEEKLVNEQNEKLKLLEQQLDE--HQAKEKALEQLLKE 1013 Query: 671 LSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAE 730 +KEL L+I + +KEQ+ + + + +E + + + E +LE++ +E Sbjct: 1014 NDGKQKELDLLISQ-QAEKEQVLQQLMEQQKQRE---YEFEQIVNEQKQKEQELEQLFSE 1069 Query: 731 KISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMED 790 + S++ ++ + +I+ + +D I E + +E + + EE ++ Sbjct: 1070 Q-SKIKHQLEQQLAQQIEKEQELDQLINEAQSRNQATFTEEQEIVLTTPKKEER----QE 1124 Query: 791 RRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIE----- 845 R R D + +++ + ++L +L + ++ K+++++E Sbjct: 1125 RTVQEGRNEDFTEGNDENEEELELRLKKEVEDLQQQLQISAQKNQESAKKIIDLEKAVQN 1184 Query: 846 HENKELQKKN-QILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLE 904 ++ E +KN + + +N+ L+ + + Y+A + N+ + E K +QL + Sbjct: 1185 YQMIERDEKNFEEIFRQNKKLEDKIKSYEMEYSA---RKNQLEHQEQTIAKLHSQLVQAD 1241 Query: 905 SNLKRITHEHQTL-----IVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVT- 958 ++L++ + + L ++ +KE E ++ IE R + L E E + Sbjct: 1242 ADLQKYIEDKRLLNDKIEALKYEKEEEIKRLKQENDIEKMSRSQSKLMESESIAFESIVG 1301 Query: 959 QLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALL 1018 + + N E+ ++ L K N L++ + + + Y E++ + Sbjct: 1302 DYKDTINMLSNKCEDYETQIQNLTKQNNVLVNSFKEIKSNLT-----SYQEELDNKEEFI 1356 Query: 1019 KQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQ-RVSKQLLDSKQH 1077 +++ +++ L + +N Y M E +L + K + +Q + K + +Q Sbjct: 1357 QKQSQDMFELQKSVNQ----YKQMAKKLEDQLKDLSNKSQEESSTLQYELEKNNILLEQK 1412 Query: 1078 NEELQILVREQDDQIKELKET-KLTFEMNIPKTE--GMIISSTIEPMSDDANNVDXXXXX 1134 N+++Q ++ +I+ L E L + N+ K E ++I + ++ Sbjct: 1413 NKDVQA----KNQEIQSLYEKISLIEKSNLQKLEDLNLVIQEEQNQRKEIQTELEQLVDK 1468 Query: 1135 XXXXXXXL-KV--QEEEEFIQERSVLQEQSA---KLNTELQECYTKIIQ-LETLNTELTG 1187 L KV Q++EEF Q + LQE S K N L+E + Q L+ N E+ Sbjct: 1469 YNQDVQELQKVMDQQQEEFTQIQQQLQESSQNQQKENLNLKEQMEHLKQQLDQKNAEI-- 1526 Query: 1188 HDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQRE 1247 V QE++ L+ L+++ END L E I D + +L K + +++ Sbjct: 1527 --VSKQEELLNLEDMLQKI--END-LKQQKHEFDLQIQKQEDSNNQHVDQLQKI-IDEKQ 1580 Query: 1248 ADFQKTEHELRVQLSAFESKYE-QLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHL 1306 + + Q S+ S+ + ++L + E N EQ+ + +LQ K+E L Sbjct: 1581 EEISLLQQNQ--QDSSLRSQEDLKILKIKLDNLVSELNN--ANEQLNEMDKELQFKDEQL 1636 Query: 1307 RNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQS 1366 + +++Y INQ+++ +++++D+K L Q+ Q++ Sbjct: 1637 KLTEKEYQMNINQLQVKQNDLQDQKKQLEEMLQEQEERYSQEITQL----QNIIDQQQED 1692 Query: 1367 ILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTIT 1426 + + + L SS + A+ ++ ++ HQL+ + ++ + ++ + Sbjct: 1693 LQGLQQN---LLGSSKIQEDKNKALTNELQQAKQEIEKMNHQLQAQHKDLEKAYQQFDDS 1749 Query: 1427 LTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKE------- 1479 Q + ++ +L + E + +DL + E + E N ET Q+E Sbjct: 1750 EKQNQQKLKSAEVKLQDLEAKYKDLQESIQIEQEKYSKDIEELQNIIETQQQEINLMEQN 1809 Query: 1480 -----SEIER-VKLIEELNVKITESVS-LNKQVAELNKALEEEVAKTNEMQTALENQEIE 1532 ++++R VK ++ N++I S L A+++K + K NE ++ + Sbjct: 1810 MTKLKNDLDRKVKDLDVKNIEIQAKDSDLESAYAQIDKIDIQYQHKLNEYESKQQELANN 1869 Query: 1533 IVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDLA 1592 L ++ L++ S++QK + +++L N ++ + R EL+ Sbjct: 1870 NNHLEGKLIELEDKYNKDVSELQKVIEQQQQDLNNLEQELYNQGSQNEETSNLRVELEKV 1929 Query: 1593 MYMLHQRD 1600 L +R+ Sbjct: 1930 SIQLDERN 1937 Score = 123 bits (297), Expect = 4e-26 Identities = 269/1333 (20%), Positives = 572/1333 (42%), Gaps = 127/1333 (9%) Query: 323 ELTKKIELLEHLNCQIRQTNKELE-NKLATMGTESKAVS--SPSKKGSPLISRKSGRNTA 379 E K+ E + L+ +TN E + + G + + +PS++ I S + Sbjct: 248 EKVKESEEGDSLSNNNEKTNFEAQIQQQVDQGDDQHLIKLLNPSEEVEASIKNNSNLHEE 307 Query: 380 SKMKSPWS--QLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISE--KDTXX 435 + +S Q+ E + Q +++++ + + E Q N + + I + ++ Sbjct: 308 NLQQSDQKDQQVKGEDIYQGNEEEMSNQDQNQEEANDQLENDSNIQENKSIKQDQEEIKT 367 Query: 436 XXXXXXXXGKDTLIAQLQLEHQQHME--GPSLIHVGTNTEDVN--EIAKVQEQL--KQEL 489 + + ++Q+E + HME G + V E+ N E++ +EQ +Q++ Sbjct: 368 PIKQQEEESQQDIQTEIQVEQENHMEKQGQQQVEVDNKNENSNLEEVSNQEEQSLREQQI 427 Query: 490 NDEIKDV-NVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFS 548 NDEI + + K +K ++Q + N + + ++ + N + +Q ++ Sbjct: 428 NDEINQLEDDKHSEQKQFDQDQQSREENIQSEVFKQDRDNHQQNEAQQYQQEEEEEQESL 487 Query: 549 KVSDSNKEIVRLTE--ELHHLSQ-KVAELEE-EKGNLQLHLVDYDSGRMIESDVYKKMIE 604 K + E+ + EL+ S + ++ + +K NL + S ++ S V Sbjct: 488 KQEEYPSELKQSMNDSELYRNSSFENSQFNQYQKDNLHNQEEEQQSPKIGSSSVLNNYKL 547 Query: 605 MENLAETRLKAISLLESQKF-------DLVQELHILQQ------------KYDEVEDKLA 645 ++ + S +S + D +QELH Q+ YD++E Sbjct: 548 EDSPSRPAAAGDSRKQSDNYEQDLYYKDHIQELHNQQEYKSEYQPSPQKEDYDDLESDGF 607 Query: 646 DISQL----QSDQVCSEIK-SVHLEEQIDALSA-SKKELALVIENLKLDKEQLYGTIKDL 699 D ++ Q+DQ + VH+E+ + A + L + N ++K+Q ++ D Sbjct: 608 DTLKMNANDQNDQSSHKYGIQVHIEKSLAPEQAVDENNLENNLLN-PIEKKQQIMSLGD- 665 Query: 700 ENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKI-QTQFGIDAKIQ 758 + +DI+N+++ + QE + M + + L N K+ Q Q D++I Sbjct: 666 -SALKDILNEIKTFKQEKQQKDPEEIVMRLSTLLQELEVQNLNNSLKLSQNQIPNDSQI- 723 Query: 759 ERDLYIENIESELSKYKSRICRLEESIAVMED-RRYSLERKADQLGSYLQEKQKAYSEYT 817 E+D + + I++ L K + + S A ++ ++ E K D+ +E QK T Sbjct: 724 EKD-FEQKIQASLQKESLKKEEKQNSEAQKDEVTEFNQEDKIDK-----EEFQKEKEIIT 777 Query: 818 IQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYN 877 +++EL+ L KQ E+E + EL+ K EN NL IS+ ++ Sbjct: 778 KEKEELIQLKEDLRKQKEDFNKQKQEVEKQKSELELK-----AENLNL-ISMQ-FEEREK 830 Query: 878 ALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIE 937 L E N + E ++ + Q ++ L+ L+ QK++ +++ E QIE Sbjct: 831 ELEEVQNTLQQQQEELSQKRKQYEQIQDKLE--------LLEQKEQHVKEREETLAQQIE 882 Query: 938 SAIRDKKV-LNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQ 996 +++K + +N++ ++ ++ +LE+ +E K + L + E N+ L+L+++ Q Sbjct: 883 F-LKEKDIYVNDREQELLDKERELESLFEEQKEKEKYLENLINEQNQ-KLKLLEQQSINQ 940 Query: 997 QTQSPDYTEQ-YINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTT 1055 Q++ EQ +INE N+ LL+Q + I N+K+ N + +V++ KL Sbjct: 941 QSEDLKLLEQQFINEQNEKLKLLEQ--QLINEQNEKLKNLE---EKLVNEQNEKLKLLEQ 995 Query: 1056 KLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQ-------IKELKETKLTFE--MNI 1106 +L+ + + + + + L ++ +EL +L+ +Q ++ +++ K+ + FE +N Sbjct: 996 QLDEHQAKEKALEQLLKENDGKQKELDLLISQQAEKEQVLQQLMEQQKQREYEFEQIVNE 1055 Query: 1107 PKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXL-KVQEEEEFIQERSVLQEQSAKLN 1165 K + + S + ++ L ++ E + + + +EQ L Sbjct: 1056 QKQKEQELEQLFSEQSKIKHQLEQQLAQQIEKEQELDQLINEAQSRNQATFTEEQEIVLT 1115 Query: 1166 TELQECYTKIIQLETLNTELTGHDVVNQEQIN-QLKSKLEQLNTENDNLLSTVAELRSSI 1224 T +E + E N + T + N+E++ +LK ++E L + L + + + S Sbjct: 1116 TPKKEERQERTVQEGRNEDFTEGNDENEEELELRLKKEVEDLQQQ---LQISAQKNQESA 1172 Query: 1225 SSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETN 1284 +D E A Q + + E +F++ + K E + S + N Sbjct: 1173 KKIID---LEKAVQNYQMIERDEKNFEEIFRQ--------NKKLEDKIKSYEMEYSARKN 1221 Query: 1285 KIVTMEQ-VTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXX 1343 ++ EQ + L ++L + L+ E + ++IE L+ E ++E++ Sbjct: 1222 QLEHQEQTIAKLHSQLVQADADLQKYIEDKRLLNDKIEALKYE-KEEEIKRLKQENDIEK 1280 Query: 1344 XXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVND-AEAKV 1402 + +E+ +++ + IN + + + VN E K Sbjct: 1281 MSRSQSKLMESESIAFESIVGDYKDTINMLSNKCEDYETQIQNLTKQNNVLVNSFKEIKS 1340 Query: 1403 LELTHQLELKDSEIY-QKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAI 1461 ++Q EL + E + QK + L + ++++ + ++L E +++DL+ + + E + Sbjct: 1341 NLTSYQEELDNKEEFIQKQSQDMFELQKSVNQYKQMAKKL---EDQLKDLSNKSQEESST 1397 Query: 1462 LRLKMHENANHYETMQKESEIERVKLIEELNVKIT--ESVSLNKQVAELNKALEEEVAKT 1519 L+ ++ +N E K+ + + + I+ L KI+ E +L K + +LN ++EE + Sbjct: 1398 LQYELEKNNILLEQKNKDVQAKNQE-IQSLYEKISLIEKSNLQK-LEDLNLVIQEEQNQR 1455 Query: 1520 NEMQTALE------NQEI-EIVTLND----EITNLQNMVRASSSKIQKHVSFASDTKQGR 1568 E+QT LE NQ++ E+ + D E T +Q ++ SS QK + + Sbjct: 1456 KEIQTELEQLVDKYNQDVQELQKVMDQQQEEFTQIQQQLQESSQNQQKENLNLKEQMEHL 1515 Query: 1569 DEQLDNTMNKELL 1581 +QLD N E++ Sbjct: 1516 KQQLDQ-KNAEIV 1527 Score = 105 bits (251), Expect = 1e-20 Identities = 252/1287 (19%), Positives = 513/1287 (39%), Gaps = 94/1287 (7%) Query: 370 ISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVIS 429 I++ S R + +SQ + + Q+T K +NE + Q ++ ++E Sbjct: 165 INQSSSRKDTQNSERLYSQGDEDFVQQNTQKHQQENESIFYKQRNQPDDQQSQEQE---- 220 Query: 430 EKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQEL 489 +K D + ++++ E + N E N A++Q+Q+ Q Sbjct: 221 QKQQDEIIAFNQEENVDNQNKEQDADNEKVKESEEGDSLSNNNEKTNFEAQIQQQVDQGD 280 Query: 490 NDE-IKDVN----VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTI 544 + IK +N V+ I+ + E+ Q +D+ D K + N + Q Q Sbjct: 281 DQHLIKLLNPSEEVEASIKNNSNLHEENLQQSDQKDQQVKGEDIYQGNEEEMSNQDQNQE 340 Query: 545 D-NFSKVSDSN-KEIVRLTEELHHLSQKVAELEEE-KGNLQLHLVDYDSGRMIESDVYKK 601 + N +DSN +E + ++ + + + EEE + ++Q + M + ++ Sbjct: 341 EANDQLENDSNIQENKSIKQDQEEIKTPIKQQEEESQQDIQTEIQVEQENHMEKQG--QQ 398 Query: 602 MIEMENLAE-TRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSE-- 658 +E++N E + L+ +S E Q ++E I + +DK ++ Q DQ E Sbjct: 399 QVEVDNKNENSNLEEVSNQEEQS---LREQQINDEINQLEDDKHSEQKQFDQDQQSREEN 455 Query: 659 IKSVHLEEQID---ALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQ 715 I+S ++ D A + + E L +E+ +K ND E N Q Sbjct: 456 IQSEVFKQDRDNHQQNEAQQYQQEEEEEQESLKQEEYPSELKQSMNDSELYRNSSFENSQ 515 Query: 716 ENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYK 775 N D L E+ S + + K++ A + +N E +L YK Sbjct: 516 FNQYQKDNLHNQEEEQQSPKIGSSSVLNNYKLEDSPSRPAAAGDSRKQSDNYEQDL-YYK 574 Query: 776 SRICRLEESIAVMEDRRYSLERK-ADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHD 834 I L + + S +++ D L S + K + + + V ++ Sbjct: 575 DHIQELHNQQEYKSEYQPSPQKEDYDDLESDGFDTLKMNANDQNDQSSHKYGIQVHIEKS 634 Query: 835 RVVEKQLLEIEHEN---KELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAES 891 E+ + E EN ++KK QI+ + L+ L++++ +K + Sbjct: 635 LAPEQAVDENNLENNLLNPIEKKQQIMSLGDSALKDILNEIKTFKQEKQQKDPEEIVMRL 694 Query: 892 ESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYE 951 + + ++++L ++LK ++ Q +K+ E +I+ + Q ES +++K +E + Sbjct: 695 STLLQELEVQNLNNSLK-LSQNQIPNDSQIEKDFEQ-KIQASLQKESLKKEEKQNSEAQK 752 Query: 952 KNI-EYVTQLEAQLQEYKNNIENLNMNVEELNKMNLEL----IDKHVQKQQTQ-SPDYTE 1005 + E+ + + +E++ E + EEL ++ +L D + QKQ+ + E Sbjct: 753 DEVTEFNQEDKIDKEEFQKEKEIITKEKEELIQLKEDLRKQKEDFNKQKQEVEKQKSELE 812 Query: 1006 QYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQ 1065 +N ++ +++++E+ +++ N +S + Q KLE +E++ Q Sbjct: 813 LKAENLNLISMQFEEREKEL----EEVQNTLQQQQEELSQKRKQYEQIQDKLELLEQKEQ 868 Query: 1066 RVSKQ---LLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMS 1122 V ++ L + +E I V +++ ++ + KE +L K + + + I + Sbjct: 869 HVKEREETLAQQIEFLKEKDIYVNDREQELLD-KERELESLFEEQKEKEKYLENLINEQN 927 Query: 1123 DDANNVDXXXXXXXXXXXXLK----VQEEEEFIQ--ERSVLQEQSAKL-NTELQECYTKI 1175 ++ L + E+ E ++ E+ ++ EQ+ KL N E + + Sbjct: 928 QKLKLLEQQSINQQSEDLKLLEQQFINEQNEKLKLLEQQLINEQNEKLKNLEEKLVNEQN 987 Query: 1176 IQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVD---QRG 1232 +L+ L +L H ++ + QL + + E D L+S AE + ++ QR Sbjct: 988 EKLKLLEQQLDEHQ-AKEKALEQLLKENDGKQKELDLLISQQAEKEQVLQQLMEQQKQRE 1046 Query: 1233 FEIAEL------WKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKI 1286 +E ++ +Q L Q ++ K +H+L QL A + + EQ LD + + Q Sbjct: 1047 YEFEQIVNEQKQKEQELEQLFSEQSKIKHQLEQQL-AQQIEKEQELDQLINEAQSRNQAT 1105 Query: 1287 VTMEQVTSLQN-KLQDKEEHL----RNLQEKYADVINQIEI---LRSEIEDEKVAFXXXX 1338 T EQ L K ++++E RN + N+ E+ L+ E+ED + Sbjct: 1106 FTEEQEIVLTTPKKEERQERTVQEGRNEDFTEGNDENEEELELRLKKEVEDLQQQL-QIS 1164 Query: 1339 XXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDA 1398 DL Q+Y QM E+ N E Q KK R N Sbjct: 1165 AQKNQESAKKIIDLEKAVQNY-QMIERDEKNFEEIFRQNKKLEDKIKSYEMEYSARKN-- 1221 Query: 1399 EAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESE 1458 +L HQ + K H L Q + + + + +IE L YEKE E Sbjct: 1222 -----QLEHQ-----EQTIAKLHS---QLVQADADLQKYIEDKRLLNDKIEALKYEKEEE 1268 Query: 1459 LAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVS-LNKQVAELNKALEEEVA 1517 I RLK + Q + E + ++++ L+ + + ++ Sbjct: 1269 --IKRLKQENDIEKMSRSQSKLMESESIAFESIVGDYKDTINMLSNKCEDYETQIQNLTK 1326 Query: 1518 KTNEMQTALENQEIEIVTLNDEITNLQNMVRASSS---KIQKHVSFASDTKQGRDEQLDN 1574 + N + + + + + + +E+ N + ++ S ++QK V+ + ++QL + Sbjct: 1327 QNNVLVNSFKEIKSNLTSYQEELDNKEEFIQKQSQDMFELQKSVNQYKQMAKKLEDQLKD 1386 Query: 1575 TMNKELLD-AVPRAELDLAMYMLHQRD 1600 NK + + + EL+ +L Q++ Sbjct: 1387 LSNKSQEESSTLQYELEKNNILLEQKN 1413 Score = 73.7 bits (173), Expect = 4e-11 Identities = 154/741 (20%), Positives = 330/741 (44%), Gaps = 100/741 (13%) Query: 152 KEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXX 211 K+ L +VK++ +E DLQE I QI + K Sbjct: 1751 KQNQQKLKSAEVKLQDLEAKYKDLQESI----QIEQEK----------YSKDIEELQNII 1796 Query: 212 EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271 E +Q++ M++N + K++ R +KD++ K++ I + + LE+A +I Sbjct: 1797 ETQQQEINLMEQNMTKL----KNDLDRKVKDLDVKNIEIQAKDSD---LESAYAQIDKID 1849 Query: 272 SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELL 331 + +L + L + I E+E+K + ++ +EL K IE Sbjct: 1850 IQYQHKLNEYESKQQELANNNNHLEGKLI--------ELEDKYNKDV---SELQKVIE-- 1896 Query: 332 EHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSS 391 Q +Q LE +L G++++ S+ + + + RN+ +K+ +L S Sbjct: 1897 -----QQQQDLNNLEQELYNQGSQNEETSNLRVELEKVSIQLDERNSEILIKN--KELDS 1949 Query: 392 ETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQ 451 D ++ + ++ + E+ IQ L K + + + E D IA Sbjct: 1950 MYEQIDKIERQYQQKLREQEIKIQDLQKLKKEYDQQLLELDNKNSQD----------IAD 1999 Query: 452 LQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVK---DLIEKLKSA 508 L+ +Q E + +D+ E K QE+ L E++ N++ DLI+K K Sbjct: 2000 LKNIIEQQQE-----DLNNMQKDLFENTKHQEE-NNNLRFELERKNIQLNSDLIQKNK-- 2051 Query: 509 EEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFS-KVSDSNKEIVRLTEELHHL 567 ++ QL+++I+ K + + +LKL+ +Q F K+ + ++ + EL Sbjct: 2052 --ELDQLHEQINKIEKQNQQKLRDQELKLQDLQNQKKEFDLKLMEQEEKNNQYITEL--- 2106 Query: 568 SQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIE-MENLAETRLKAISLLESQKFDL 626 QK+ E ++E N + ++G E + + IE +N + + I+ E + D+ Sbjct: 2107 -QKIIEQQQEDLNKMEQCLYENNGSQDEINNLRSEIEKQQNELDEKSNEINQKEKELEDM 2165 Query: 627 VQELHILQQKY-DEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENL 685 Q++ ++++Y D++ + + + +LQ+ +EI EE + EL +I+ Sbjct: 2166 FQQMQEVERQYQDKLNETESKLKELQNQN--NEIIG-KFEESEQKSNFHISELQKIIDQQ 2222 Query: 686 KLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKIS---ELLAKINHE 742 + ++ + D +E+ N L+ ++ T +LE+ +AE +S EL +K ++ Sbjct: 2223 QEMIGRMDQDLFDTSRQQEE-NNSLRMELERK---TLQLEQRNAEILSKNKELESK--YD 2276 Query: 743 EQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQL 802 + KI+ Q+ K+++ +L ++++++ + + R+ EE+ +E + E + +L Sbjct: 2277 QLDKIERQY--QQKLRDFELKQQDLQNQKKELELRLLEQEENGGSLEKLQREFEMQKKEL 2334 Query: 803 GSYLQEKQ-----------KAYSEYTIQEDELVNRL-AVLMDHDRVVEKQLL---EIEHE 847 + L ++Q + +Y Q + NR+ ++ +DH ++K + E+ + Sbjct: 2335 ENILDKQQIEIEELNDKLIRQREDYEYQLAQANNRIQSIELDHKTEIKKLMKLQEELRLQ 2394 Query: 848 NKELQKKNQILLEENQNLQIS 868 N++++ K + L E+++N+Q S Sbjct: 2395 NRDMENKYERLKEDHKNIQNS 2415 Score = 65.7 bits (153), Expect = 1e-08 Identities = 135/650 (20%), Positives = 264/650 (40%), Gaps = 54/650 (8%) Query: 148 SNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXX 207 S I+E N + Q ++ +ME + L+ ++ K + ++ KN Sbjct: 1786 SKDIEELQNIIETQQQEINLMEQNMTKLKNDLDRKVKDLDVKN---IEIQAKDSDLESAY 1842 Query: 208 XXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLL-KDIESKDVRISSLEEANKLLEAARFE 266 + Q K+ E + + + E + L K IE +D + E K++E + + Sbjct: 1843 AQIDKIDIQYQHKLNE-YESKQQELANNNNHLEGKLIELEDKYNKDVSELQKVIEQQQQD 1901 Query: 267 ISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTK 326 + + L QEL L K SI+ E +EI K E+ +M E Sbjct: 1902 L----NNLEQELYNQGSQNEETSNLRVELEKVSIQLD-ERNSEILIKNK-ELDSMYEQID 1955 Query: 327 KIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPW 386 KIE ++R+ ++++ + + K S I+ +N + + Sbjct: 1956 KIE--RQYQQKLREQEIKIQDLQKLKKEYDQQLLELDNKNSQDIA--DLKNIIEQQQEDL 2011 Query: 387 SQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGK- 445 + + + ++ N N +LE LN DL+ K + + K Sbjct: 2012 NNMQKDLFENTKHQEENNNLRFELERKNIQLNSDLIQKNKELDQLHEQINKIEKQNQQKL 2071 Query: 446 -DTLIAQLQLEHQQHMEGPSLI-HVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIE 503 D + L++Q+ L+ N + + E+ K+ EQ +++LN ++ + Sbjct: 2072 RDQELKLQDLQNQKKEFDLKLMEQEEKNNQYITELQKIIEQQQEDLN------KMEQCLY 2125 Query: 504 KLKSAEEQITQLNDEIDAANKNMIKVKSNH-KLKLKQMQKTIDNFSKVSDSNKEIVRLTE 562 + ++++I L EI+ +N + KSN K K+++ +V ++ + TE Sbjct: 2126 ENNGSQDEINNLRSEIE-KQQNELDEKSNEINQKEKELEDMFQQMQEVERQYQDKLNETE 2184 Query: 563 ----ELHHLSQKVA---ELEEEKGNLQL----HLVDYDS---GRMIESDVYKKMIEMENL 608 EL + + ++ E E+K N + ++D GRM + D++ + E Sbjct: 2185 SKLKELQNQNNEIIGKFEESEQKSNFHISELQKIIDQQQEMIGRM-DQDLFDTSRQQEEN 2243 Query: 609 AETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQI 668 R++ LE + L Q + K E+E K + +++ Q +++ L++Q Sbjct: 2244 NSLRME----LERKTLQLEQRNAEILSKNKELESKYDQLDKIER-QYQQKLRDFELKQQ- 2297 Query: 669 DALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMS 728 L KKEL L + + + L ++ E K+++ N L E +L DKL + Sbjct: 2298 -DLQNQKKELELRLLEQEENGGSLEKLQREFEMQKKELENILDKQQIEIEELNDKLIR-Q 2355 Query: 729 AEKISELLAKINHEEQS---KIQTQFGIDAKIQERDLYIENIESELSKYK 775 E LA+ N+ QS +T+ K+QE +L ++N + E +KY+ Sbjct: 2356 REDYEYQLAQANNRIQSIELDHKTEIKKLMKLQE-ELRLQNRDME-NKYE 2403 >UniRef50_A2FKU0 Cluster: Viral A-type inclusion protein, putative; n=1; Trichomonas vaginalis G3|Rep: Viral A-type inclusion protein, putative - Trichomonas vaginalis G3 Length = 1688 Score = 170 bits (414), Expect = 2e-40 Identities = 315/1583 (19%), Positives = 680/1583 (42%), Gaps = 138/1583 (8%) Query: 55 ERAQKCLENAALVSKRIKEHRKATAELLGRPFVPGISESLANTLKQK-EILMEKIKQYKE 113 E+ Q+ + + L+ +R + K+ E + ++ L N+ K K E +K+++ E Sbjct: 8 EQKQELMNESLLLKERFDDDLKSEHEKNKIKYEENLN--LINSQKSKLEEEKDKLEKDLE 65 Query: 114 LSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNALSVLQVKMKIMETTIL 173 K + + L ++ L IK+ D L K + Sbjct: 66 KLKEENQKQIDDLQNKISKVENEKKSNLKEIEDLMKQIKDLDQQKIDLSKKFNENQLKNE 125 Query: 174 DLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWK 233 + +K+N DQI + + + + M+ +++ I + Sbjct: 126 ENIQKLN--DQIENLQKEKENLINEHKNELNNLSISLQDQMESNMSDLEKKLIQANKNHQ 183 Query: 234 DE---KQRLLKDIES----KDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXX 286 +E KQ + D+++ + IS+L++ + L++ + S KL ++ + Sbjct: 184 NEMHQKQMEILDLQNLVDKQKGEISNLQKRIQKLDSNNSDNSDMIDKLKSQILELENTNN 243 Query: 287 XXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIA-NMTELTKKIELLEHLNCQIRQTNKEL 345 AK + + + + +EE + E N ++ + ++ L Q + + L Sbjct: 244 QIEIDLEN-AKSNNDKLNVKISLLEENYNKENELNKNKIENLQKQIKELQDQKAEIEENL 302 Query: 346 ENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKN 405 EN++ + + + + K + K+ R +++ S++ D ++K +N Sbjct: 303 ENQILLLKKKINELEAELMKNKIDLD-KNQRQFDNELGKSHSEIQKMNQKLDENQKKYQN 361 Query: 406 EIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSL 465 EI KL + SL ++ + + E K + ++ E Q+H + + Sbjct: 362 EIQKLNELNDSLKNEVKKYQNELQEN-------------KKKYVQDMENEMQEHQK--DI 406 Query: 466 IHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKN 525 I + + E++ + + + K L + + D +++I+ + S I + +ID ++ Sbjct: 407 ISLNQSIEEIQKAKENSDAEKHNLENLVNDK--EEIIQNMNST---IKKYQGQIDDLSEK 461 Query: 526 MIKVKSNHKLKLKQMQKT-IDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLH 584 + ++ N+K + K ++K + N + ++ K+ ++ ++LSQ +E+ E K N Q Sbjct: 462 IKILEENNKYQEKDLEKIKLQNKIDLLENQKQEIQ-----NNLSQTKSEISELKDNNQKL 516 Query: 585 LVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKL 644 L + S +M + + Y M E E LA + K + K +L + L I K E D L Sbjct: 517 LTN--SQKMTDDNQYL-MKENEKLASEKQKLTEECQKLKENLTK-LQIQLDKIKEDNDNL 572 Query: 645 A-DISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDK 703 D ++LQ+ + + L I L + KE L I N +K++L I L+ +K Sbjct: 573 ENDNNKLQNKLNEMQNQISDLTSTISKLESDLKEKDL-ISNENKEKDEL---IDMLKREK 628 Query: 704 EDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQ-------SKIQTQFGIDAK 756 E+ + K + + Q ++ K + ++I E+ +K N ++ S Q Q A+ Sbjct: 629 ENQLQKQKEFFQSEIENLQKSKDKEIKEIEEVKSKENERQKINFDETISNFQNQI---AE 685 Query: 757 IQ-ERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAY-S 814 +Q E+ +EN+ +K + +L+ I +E + ++L + ++ E++K + Sbjct: 686 LQNEKQKMMENLNQNQAK-NLQTAQLKLDIQKLEGKIFTLNDEKAKIEKQNSEREKRFID 744 Query: 815 EYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQ 874 EY Q+ + N L H ++K+ EI ++L NQIL + + L + + Sbjct: 745 EYEAQKRKFDNDL-----HHLYLQKEE-EIASAKRDLN--NQILDLKKEYLNDLAEERKD 796 Query: 875 HYNALVE----KANRTDLAE---SESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIED 927 H + E K DL E SE Q Q+ DL+S + ++ E + L + K + D Sbjct: 797 HQQKIFEHKDEKQKIEDLNEKQKSEILSLQKQIEDLQSQIDKLQKEKEILEKENTKHLVD 856 Query: 928 LEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLE 987 E N + E +K N+ + +Y + E + N+I+N N N + + + Sbjct: 857 NE---NLKQEILQNSQKFANDLQNISNDYSKKFEEEF----NDIKNRNKNEIQKLQNQIS 909 Query: 988 LIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYE 1047 L++ QK Q ++ ++I L + +I ALN K+N+ Q++ + +D Sbjct: 910 LLENEKQKLQNDLNILEKESDSQIKSLQT---ESKSQISALNNKLNDLQINRDGLQAD-N 965 Query: 1048 SKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIP 1107 S L + LEN++ ++ K L++K N+ L+ + + +L ++K+T N+ Sbjct: 966 SNLKNKLSDLENVKSSLES-DKSELENK--NKNLRDFLNNLNASNTDL-QSKIT---NLE 1018 Query: 1108 KTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEE-EFIQERSV-LQEQSAKLN 1165 K + + + + +D+ + ++ Q++E + + E+ + L E + + Sbjct: 1019 KVKNDLENKMSKLKNDNEKLIQKLAQNQENHEQVVERQKKEIDSLSEKQISLVEDNKNQS 1078 Query: 1166 TELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSIS 1225 +Q K+ Q+E N +L +N Q + + K ++L+ END S + E SS+ Sbjct: 1079 KNIQNLLEKLSQIENQNQQLQKD--LNDLQNDNISLK-QKLSEENDKSKSILEE-NSSLK 1134 Query: 1226 SAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNK 1285 + + + G + E Q ++++++D Q ++++ + E + D + S EE K Sbjct: 1135 NEIQEIGKQNTEFQIQ-ISKQKSDLQNQKNDIDKLMLELEHLRTENKD-ISSHMNEE--K 1190 Query: 1286 IVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXX 1345 + +E + N++ +K++ + L++ +A Q+EI + + ++ F Sbjct: 1191 LKEIEDKSKELNEIFEKQK--KELEKNFA---KQVEIEKLKSDNLSKDFSISQGNLEKEI 1245 Query: 1346 XXXXXDLRTENQSYK---QMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDA---- 1398 + +EN+ ++ Q +++ + + +N +L + +D Sbjct: 1246 GHLKNVIMSENKRHQAELQNNKKNFIELQNQNQKLISEISSLKDEKFKIQEQKDDQISGL 1305 Query: 1399 EAKVLELTHQLELK------DSEIYQKTHEYTITLTQRNDEFENVR----QQLVEYEKRI 1448 K+ L ++LE K + E QK E +L + N++ + + +Q++ + + Sbjct: 1306 HKKLNTLQNELENKSNLLNEEKETIQKLKEIISSLQKENEDLKLQKPIFDEQVMHSNELL 1365 Query: 1449 EDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAEL 1508 E ESE+ L K++ N + ++KE +L E + K ++ Q+ + Sbjct: 1366 EKQKENHESEIGGLLEKINNLENEKQKLEKELYKMEDELDETVQYKKRLEEDISNQMKKH 1425 Query: 1509 NKALEEEVAKTN-EMQTALENQ-EIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQ 1566 + ++ ++ K + E++ L+ Q EIE+ E ++N + A +K+VS S+ K Sbjct: 1426 KQEIDNQMKKNDLEIENLLKKQKEIEL-----ERQEIENKLIAQK---EKYVSELSNLKF 1477 Query: 1567 GRDEQLDNTMNKELLDAVPRAEL 1589 + N++N E + + E+ Sbjct: 1478 DLQNEKSNSLNLEKIKRQNQIEI 1500 Score = 167 bits (405), Expect = 3e-39 Identities = 286/1351 (21%), Positives = 582/1351 (43%), Gaps = 123/1351 (9%) Query: 147 LSNTIKEKDNALSVLQVK-MKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXX 205 L N +K+ N L + K ++ ME + + Q+ I +Q IE KA Sbjct: 373 LKNEVKKYQNELQENKKKYVQDMENEMQEHQKDIISLNQSIEEIQKAKENSDAEKHNLEN 432 Query: 206 XXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKD---IESKDVRISSLEEANKLLEA 262 E+ Q M + + + + EK ++L++ + KD+ L+ LLE Sbjct: 433 LVNDK-EEIIQNMNSTIKKYQG-QIDDLSEKIKILEENNKYQEKDLEKIKLQNKIDLLEN 490 Query: 263 ARFEIS-------LEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGS 315 + EI E S+L ++ L K++ E EK ++ E+ Sbjct: 491 QKQEIQNNLSQTKSEISELKDNNQKLLTNSQKMTDDNQYLMKEN-EKLASEKQKLTEECQ 549 Query: 316 LEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTE-SKAVSSPSKKGSPLISRKS 374 N+T+L +++ ++ N + N +L+NKL M + S S+ SK S L + Sbjct: 550 KLKENLTKLQIQLDKIKEDNDNLENDNNKLQNKLNEMQNQISDLTSTISKLESDLKEKDL 609 Query: 375 GRNTASKMKSPWSQLSSETLNQ-DTDKKINKNEIAKLEMVIQSLNKDLVDKEYVIS-EKD 432 N + L E NQ K+ ++EI L+ +S +K++ + E V S E + Sbjct: 610 ISNENKEKDELIDMLKREKENQLQKQKEFFQSEIENLQ---KSKDKEIKEIEEVKSKENE 666 Query: 433 TXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLK-QELND 491 IA+LQ E Q+ ME N + Q +L Q+L Sbjct: 667 RQKINFDETISNFQNQIAELQNEKQKMME-------NLNQNQAKNLQTAQLKLDIQKLEG 719 Query: 492 EIKDVN-VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKV 550 +I +N K IEK S E+ + DE +A K K ++ L +QK + S Sbjct: 720 KIFTLNDEKAKIEKQNSEREK--RFIDEYEAQ-----KRKFDNDLHHLYLQKEEEIASAK 772 Query: 551 SDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDY-DSGRMIESDVYKKMIEMENLA 609 D N +I+ L +E + +L EE+ + Q + ++ D + IE K+ E+ +L Sbjct: 773 RDLNNQILDLKKEY------LNDLAEERKDHQQKIFEHKDEKQKIEDLNEKQKSEILSLQ 826 Query: 610 ETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQI- 668 K I L+SQ L +E IL++ E L D L+ + + + K + + I Sbjct: 827 ----KQIEDLQSQIDKLQKEKEILEK---ENTKHLVDNENLKQEILQNSQKFANDLQNIS 879 Query: 669 -DALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKM 727 D ++E + K + ++L I LEN+K+ + N L +E+ L+ Sbjct: 880 NDYSKKFEEEFNDIKNRNKNEIQKLQNQISLLENEKQKLQNDLNILEKESDSQIKSLQTE 939 Query: 728 SAEKISELLAKINHEEQSKIQTQ---FGIDAKIQERDLYIENIESELSKYKSRICRLEES 784 S +IS L K+N + ++ Q + K+ + + ++ES+ S+ +++ L + Sbjct: 940 SKSQISALNNKLNDLQINRDGLQADNSNLKNKLSDLENVKSSLESDKSELENKNKNLRDF 999 Query: 785 IAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMD-HDRVVEKQLLE 843 + + L+ K L + + S+ ++L+ +LA + H++VVE+Q E Sbjct: 1000 LNNLNASNTDLQSKITNLEKVKNDLENKMSKLKNDNEKLIQKLAQNQENHEQVVERQKKE 1059 Query: 844 IEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDL 903 I+ L +K L+E+N+N ++ L+EK ++ E+++ + Q L DL Sbjct: 1060 ID----SLSEKQISLVEDNKN-------QSKNIQNLLEKLSQ---IENQNQQLQKDLNDL 1105 Query: 904 ES---NLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQL 960 ++ +LK+ E K K I +E N+ +++ I++ N +++ I ++ Sbjct: 1106 QNDNISLKQKLSEEN----DKSKSI----LEENSSLKNEIQEIGKQNTEFQIQI---SKQ 1154 Query: 961 EAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEI--NKLNALL 1018 ++ LQ KN+I+ L + +E L N + I H+ +++ + + + +NEI + L Sbjct: 1155 KSDLQNQKNDIDKLMLELEHLRTENKD-ISSHMNEEKLKEIEDKSKELNEIFEKQKKELE 1213 Query: 1019 KQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKL--ENM--EEEMQRVSKQLLDS 1074 K +++ K +N + + E ++ + EN + E+Q K ++ Sbjct: 1214 KNFAKQVEIEKLKSDNLSKDFSISQGNLEKEIGHLKNVIMSENKRHQAELQNNKKNFIEL 1273 Query: 1075 KQHNEELQILVREQDDQIKELKETK------LTFEMNIPKTEGMIISSTIEPMSDDANNV 1128 + N++L + D+ +++E K L ++N + E S+ + + + Sbjct: 1274 QNQNQKLISEISSLKDEKFKIQEQKDDQISGLHKKLNTLQNELENKSNLLNEEKETIQKL 1333 Query: 1129 DXXXXXXXXXXXXLKVQE---EEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTEL 1185 LK+Q+ +E+ + +L++Q +E+ KI LE +L Sbjct: 1334 KEIISSLQKENEDLKLQKPIFDEQVMHSNELLEKQKENHESEIGGLLEKINNLENEKQKL 1393 Query: 1186 TGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQ 1245 ++++++ ++L + N + + + I + + + EI L K+ Q Sbjct: 1394 EKELYKMEDELDETVQYKKRLEEDISNQMK---KHKQEIDNQMKKNDLEIENLLKK---Q 1447 Query: 1246 READFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEH 1305 +E + ++ E+ +L A + KY L +++ Q E + + +E++ QN+++ Sbjct: 1448 KEIELER--QEIENKLIAQKEKYVSELSNLKFDLQNEKSNSLNLEKI-KRQNQIE----- 1499 Query: 1306 LRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQ 1365 +++LQ+K D+ + ++ E+++++ + +L+ KQ+ E Sbjct: 1500 IKSLQDKLNDLQRMLNNIQKELKEKEDSHQNELEKIRERHRNELTNLQ------KQLTEH 1553 Query: 1366 SILNINEEN--AQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEY 1423 I N+ +N +LK+ + +D +++ +L ++LE K +E+ ++ E Sbjct: 1554 EIQNLKLQNDMEKLKRKLSENGEKKLDTQSKFDDLSSELEKLRYELEEKQNEVRKRDLEI 1613 Query: 1424 TITLTQRNDEFENVRQQLVEYEKRIEDLTYE 1454 L RN+E + R+++ +R++ Y+ Sbjct: 1614 D-ELNHRNEELQTNREEITHRSQRVKPEFYD 1643 Score = 153 bits (372), Expect = 3e-35 Identities = 204/1007 (20%), Positives = 458/1007 (45%), Gaps = 100/1007 (9%) Query: 632 ILQQKYDEVEDKLADISQLQSDQVCSEIKSVH------LEEQIDALSASKKELALVIENL 685 +LQ + +E + +L + S L ++ ++KS H EE ++ +++ K +L + L Sbjct: 1 MLQDEIEEQKQELMNESLLLKERFDDDLKSEHEKNKIKYEENLNLINSQKSKLEEEKDKL 60 Query: 686 KLD----KEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINH 741 + D KE+ I DL+N + N+ ++ ++E DL +++ + +KI +L K N Sbjct: 61 EKDLEKLKEENQKQIDDLQNKISKVENEKKSNLKEIEDLMKQIKDLDQQKI-DLSKKFN- 118 Query: 742 EEQSKIQTQFGIDAKIQERDLYIENIESE----LSKYKSRICRLEESIA-VMEDRRYSLE 796 + Q + IQ+ + IEN++ E ++++K+ + L S+ ME LE Sbjct: 119 ------ENQLKNEENIQKLNDQIENLQKEKENLINEHKNELNNLSISLQDQMESNMSDLE 172 Query: 797 RKADQLGSYLQEK--QKAYSEYTIQE---------DELVNRLAVL----MDHDRVVEK-- 839 +K Q Q + QK +Q L R+ L D+ +++K Sbjct: 173 KKLIQANKNHQNEMHQKQMEILDLQNLVDKQKGEISNLQKRIQKLDSNNSDNSDMIDKLK 232 Query: 840 -QLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVE-KANRTDLAESESTKYQ 897 Q+LE+E+ N +++ + N L + +S ++++YN E N+ + + + + Q Sbjct: 233 SQILELENTNNQIEIDLENAKSNNDKLNVKISLLEENYNKENELNKNKIENLQKQIKELQ 292 Query: 898 TQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYV 957 Q ++E NL E+Q L+++KK I +LE E ++++ + + K+ + Sbjct: 293 DQKAEIEENL-----ENQILLLKKK--INELEAELMKNKIDLDKNQRQFDNELGKSHSEI 345 Query: 958 TQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNAL 1017 ++ +L E + +N +++LN++N + + V+K Q + + ++Y+ ++ Sbjct: 346 QKMNQKLDENQKKYQN---EIQKLNELN-DSLKNEVKKYQNELQENKKKYVQDMEN---E 398 Query: 1018 LKQKDEEIIALNQKINNAQVSYMSMVSD---YESKLAQFTTKLENMEEEMQRVSKQLLDS 1074 +++ ++II+LNQ I Q + + ++ E+ + ++NM +++ Q+ D Sbjct: 399 MQEHQKDIISLNQSIEEIQKAKENSDAEKHNLENLVNDKEEIIQNMNSTIKKYQGQIDDL 458 Query: 1075 KQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXX 1134 +E+++IL Q K+L++ KL ++++ + + I + + + + + Sbjct: 459 ---SEKIKILEENNKYQEKDLEKIKLQNKIDLLENQKQEIQNNLSQTKSEISELKDNNQK 515 Query: 1135 XXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQE 1194 + + + ++E L + KL E Q+ + +L+ ++ + + Sbjct: 516 LLTNSQKM-TDDNQYLMKENEKLASEKQKLTEECQKLKENLTKLQIQLDKIKEDNDNLEN 574 Query: 1195 QINQLKSKLEQLNTENDNLLSTVAELRSSI--SSAVDQRGFEIAELWKQHLAQREADFQK 1252 N+L++KL ++ + +L ST+++L S + + E EL ++E QK Sbjct: 575 DNNKLQNKLNEMQNQISDLTSTISKLESDLKEKDLISNENKEKDELIDMLKREKENQLQK 634 Query: 1253 TEHELRVQLSAFESKYEQLLDSVQ--SSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQ 1310 + + ++ + ++ + ++ S + E KI E +++ QN++ + L+N + Sbjct: 635 QKEFFQSEIENLQKSKDKEIKEIEEVKSKENERQKINFDETISNFQNQIAE----LQNEK 690 Query: 1311 EKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNI 1370 +K + +NQ ++ ++ + A D + + + KQ E+ I Sbjct: 691 QKMMENLNQ-----NQAKNLQTAQLKLDIQKLEGKIFTLNDEKAKIE--KQNSEREKRFI 743 Query: 1371 NEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQ-LELKDSEIYQKTHEYTITLTQ 1429 +E AQ +K + A AK +L +Q L+LK + E Sbjct: 744 DEYEAQKRKFDNDLHHLYLQKEEEI--ASAK-RDLNNQILDLKKEYLNDLAEE------- 793 Query: 1430 RNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIE 1489 R D + + + E +K IEDL +++SE+ L+ ++ + + + +QKE EI +E Sbjct: 794 RKDHQQKIFEHKDEKQK-IEDLNEKQKSEILSLQKQIEDLQSQIDKLQKEKEI-----LE 847 Query: 1490 ELNVK-ITESVSLNKQVAELNKALEEEVAK-TNEMQTALENQEIEIVTLN-DEITNLQNM 1546 + N K + ++ +L +++ + ++ ++ +N+ E + +I N +EI LQN Sbjct: 848 KENTKHLVDNENLKQEILQNSQKFANDLQNISNDYSKKFEEEFNDIKNRNKNEIQKLQNQ 907 Query: 1547 VRASSSKIQKHVSFASDTKQGRDEQLDN--TMNKELLDAVPRAELDL 1591 + ++ QK + + ++ D Q+ + T +K + A+ DL Sbjct: 908 ISLLENEKQKLQNDLNILEKESDSQIKSLQTESKSQISALNNKLNDL 954 >UniRef50_UPI00006CD895 Cluster: hypothetical protein TTHERM_00521980; n=1; Tetrahymena thermophila SB210|Rep: hypothetical protein TTHERM_00521980 - Tetrahymena thermophila SB210 Length = 2741 Score = 170 bits (413), Expect = 3e-40 Identities = 266/1350 (19%), Positives = 581/1350 (43%), Gaps = 117/1350 (8%) Query: 251 SSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEI 310 + L E N+++ + EI KL ++ +Q Q+ E+ ++ Sbjct: 810 NELNERNEVIINMKMEIQSLEQKLQEKEKQIKKIQSEMVEVEEEKIHQAKLVKSLEQFQV 869 Query: 311 EEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLI 370 ++K E E+ +K+ +E + ++ + N ELE +L + +K Sbjct: 870 DKKARNE-----EILEKVIEMEKIQKKLNKRNIELEEELKKYKETEINLEVQIEK----- 919 Query: 371 SRKSGRNTASKMKSPWSQLSSETLNQDTDKKIN--KNEIAKLEMVIQSLNKDLVDKEYVI 428 ++K G ++ + NQ +++KI K +IA L+ I +L +L Sbjct: 920 AKKQGDEKTQDLQKKIKDFEKQ--NQQSNQKIGELKEQIATLQSQISNLQHELQQ----- 972 Query: 429 SEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEG-PSLIHVGTNTEDVNEIAKVQEQLKQ 487 EKD + IAQL+ Q+ ++ N E + ++Q +Q Sbjct: 973 -EKDKNIKQEMDFKKSNENDIAQLEFSLQKQIKNLQQEKEDAVNAERLKYEKEIQAIRRQ 1031 Query: 488 ELNDE-IKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSN---HKLKLK-QMQK 542 + ++E I + + L+ +L ++Q+ QL ++ + + K + KL Q+Q+ Sbjct: 1032 DESEEYISEEKYQKLLSELNIKDQQVKQLQQQLQEQEIALQESKEALYIERQKLDAQLQE 1091 Query: 543 TIDNFS-KVSDSNK-EIVRLTEELHH-LSQKVAELEEEKGNLQLHLVDYDSGRMIESDVY 599 + N S ++ N+ EI + ++ L K A+ E+EK Q + + I++ + Sbjct: 1092 QLKNQSIELKKVNEQEIQNVVDQFEKILKDKAAQFEQEKS--QKNEAFEKELKQIQNR-F 1148 Query: 600 KKMIEMENLAETRLKAISLLESQKF-DLVQELHILQQKYDEVEDKLADISQLQSDQVCSE 658 K+ E N R+ ++ +E + +EL L QK E+E K A Q++ +++ SE Sbjct: 1149 KEHEEEINRENKRVVEVNQMELNGLKENNEELQSLNQKL-EIELKQA---QIRENELQSE 1204 Query: 659 IKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENM 718 +++ + ++ +AS E ++ L+ +K Q+ + + + E + Q+ Sbjct: 1205 NENLKTKIELIESNASS-ENKTIVNGLQTEKRQIEQNLSQAKRNLELSEKNILELKQKIT 1263 Query: 719 DLTDKLEKMSAEK---ISELLA---KINHEEQSKIQTQFGIDAKIQERDLYIENIESELS 772 L ++ E +S E+ I +L +IN +Q Q Q + IQ++D YI+ +E+E++ Sbjct: 1264 KLEEENESISLERSNLIKQLQGNQDEINDVKQDNQQKQSELAQHIQQKDYYIQELENEIT 1323 Query: 773 KYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRL----- 827 KS+I + + ++ L K +L QEK+K + + + +E + +L Sbjct: 1324 NLKSKIDQSNQETQIITQESIQLNHKISELQQLNQEKEKRIEQISKKAEEAIIQLQKEHQ 1383 Query: 828 ------------AVLMDHDR---VVEKQLLEIEHENKE----LQKKNQILLEENQNLQIS 868 +L +++ +E+Q++ + +N++ +K+ L E + +IS Sbjct: 1384 QKIEEVIHQSKGEILEGYNKQRAQLEQQIVFLNQQNEQTKQSFEKQIHSLQNEKEQQKIS 1443 Query: 869 LSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDL 928 + ++ L E+ + + ES K Q + LE + + + + + + EI+ + Sbjct: 1444 FENQKEQQRILFEQEKQQLAKQFESQKEQNK-NALEKQINELNEKLNSSKNKYESEIQAI 1502 Query: 929 EIEFNTQIESAIRDKKV-LNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLE 987 E+N +I+ + K+ +N+ + + I+ + Q L N + N +++ + N Sbjct: 1503 NKEYNKKIQDTVEQTKIEMNQTFSQQIKKLEQQLNDLTRQNNEFKQNNNELQKQIQSNQV 1562 Query: 988 LIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYE 1047 ++ VQ+ + +Q IN++ N + + ++I L ++IN + + + + Sbjct: 1563 EAEQKVQQLKQNHQKQLDQSINQVT--NEITESFKQQIATLEKQIN---LLKDTQAASSQ 1617 Query: 1048 SKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIP 1107 ++ ++FT ++ ++ E++ + ++ QH +L L ++ I+E++E + N Sbjct: 1618 NQTSKFTQEINSLSEQIVSLQQENQVLNQHKRDLDSLNQKLQQNIQEIQENLNQSQKNNI 1677 Query: 1108 KTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTE 1167 K E I+ + + + ++ L +E++ +++ + L+ Q +L Sbjct: 1678 KLES-IVKDSQQKLEQQVKILE-----EEKERYSLIEKEKQSILEKNNQLENQMEELKRN 1731 Query: 1168 LQECYTKIIQLETL--NTELTGHDVVNQEQINQLKSKLEQLNTENDNL------LSTVAE 1219 LQ+ ++ Q E N + N + + Q S L Q+N N+ + L + Sbjct: 1732 LQQFKVQVQQTEQKQENEAFSKLQNENNDLVQQNNSLLFQINELNNQIHLLEDKLQKSSI 1791 Query: 1220 LRSSISSAVDQRGFEIAEL--WKQHLA--QREADFQKTEHELRVQLSAFESKYEQLLDSV 1275 L+ + +Q+G EI + + LA Q D + + E + ++ A K++ S+ Sbjct: 1792 LQGKQITTENQQGEEIFDFEDFADELAASQNAKDKSRQDKEKKSEMVADSGKFKLNFASI 1851 Query: 1276 QSSTQEETNKIV---TMEQVTSLQNK------LQDKEEHLRNLQE--KYADVINQ----- 1319 Q++ + +++ M+Q ++NK + D ++ + QE K+ D I Q Sbjct: 1852 QNNFDNDKDRMQIKRDMQQQQQIKNKEANDYFVDDDDDFDDSNQEKDKFKDQIIQEQGIA 1911 Query: 1320 IEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINE-ENAQLK 1378 IE ++EI + K L + YKQ ++Q+ LNINE +N + Sbjct: 1912 IEGQKNEISELKNQIDMMFQDINSQREYIQY-LESLVDEYKQKEQQNPLNINEFDNQGGQ 1970 Query: 1379 KSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVR 1438 + ++ + ++K+ ++ E ++EI ++ I L + +N Sbjct: 1971 QQEHFVEQSDASPNTKILNLKSKLADVQ---ENHETEIL-NLNQQLIALKEEIKGLKNHI 2026 Query: 1439 QQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITES 1498 L++ +E EKE+++ L +N N + + +I+ KL +L + + Sbjct: 2027 ADLMQANDDLELRIEEKENQILQLHENQQDNVNEEQIGVLQEQIQ--KLQNKLRRQEEDM 2084 Query: 1499 VSLNKQVAELNKALEEEVAKTNEMQTALEN 1528 L + LNK ++E + K Q E+ Sbjct: 2085 AYLQQVNQNLNKQIDEYMKKLKMKQPGSES 2114 Score = 160 bits (389), Expect = 3e-37 Identities = 260/1314 (19%), Positives = 550/1314 (41%), Gaps = 102/1314 (7%) Query: 316 LEIANMTELTKKIELLEHLNCQIRQTNKELENKL-------ATMGTESKAVSSPSKKGSP 368 +++ N + KK ++ L +++Q N+E +N+L M E +++ ++ Sbjct: 779 IQLQNENHILKKNQIAPELFEKMQQENREAQNELNERNEVIINMKMEIQSLEQKLQEKEK 838 Query: 369 LISR-KSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEI----AKLEMVIQSLNKDLVD 423 I + +S + K ++L DKK EI ++E + + LNK ++ Sbjct: 839 QIKKIQSEMVEVEEEKIHQAKLVKSLEQFQVDKKARNEEILEKVIEMEKIQKKLNKRNIE 898 Query: 424 -----KEYVISEKDTXXXXXXXXXXGKD-TLIAQLQLEHQQHMEGPSLIHVGTNTEDVNE 477 K+Y +E + G + T Q +++ + S +G E + Sbjct: 899 LEEELKKYKETEINLEVQIEKAKKQGDEKTQDLQKKIKDFEKQNQQSNQKIGELKEQIAT 958 Query: 478 IAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSN----H 533 + L+ EL E KD N+K ++ KS E I QL + KN+ + K + Sbjct: 959 LQSQISNLQHELQQE-KDKNIKQEMDFKKSNENDIAQLEFSLQKQIKNLQQEKEDAVNAE 1017 Query: 534 KLKLKQMQKTI--DNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSG 591 +LK ++ + I + S+ S ++ +L EL+ Q+V +L+++ ++ L + Sbjct: 1018 RLKYEKEIQAIRRQDESEEYISEEKYQKLLSELNIKDQQVKQLQQQLQEQEIALQESKEA 1077 Query: 592 RMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELH-ILQQK---YDEVEDKLADI 647 IE ++ E L ++ + E + ++V + IL+ K +++ + + + Sbjct: 1078 LYIERQKLDAQLQ-EQLKNQSIELKKVNEQEIQNVVDQFEKILKDKAAQFEQEKSQKNEA 1136 Query: 648 SQLQSDQVCSEIKSVHLEEQIDALSASKKEL-ALVIENLKLDKEQLYGTIKDLENDKEDI 706 + + Q+ + K H EE+I+ + E+ + + LK + E+L + LE + + Sbjct: 1137 FEKELKQIQNRFKE-H-EEEINRENKRVVEVNQMELNGLKENNEELQSLNQKLEIELKQA 1194 Query: 707 MNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIEN 766 + EN +L K+E + + SE +N + K Q I+ + + +E Sbjct: 1195 QIRENELQSENENLKTKIELIESNASSENKTIVNGLQTEKRQ----IEQNLSQAKRNLEL 1250 Query: 767 IESELSKYKSRICRLEESIAVMEDRRYSLERK--ADQLGSYLQEKQKAYSEYTIQEDELV 824 E + + K +I +LEE E+ SLER QL E + ++ EL Sbjct: 1251 SEKNILELKQKITKLEE-----ENESISLERSNLIKQLQGNQDEINDVKQDNQQKQSELA 1305 Query: 825 NRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKAN 884 + + + +E ++ ++ + + ++ QI+ +E+ L +S++QQ N EK Sbjct: 1306 QHIQQKDYYIQELENEITNLKSKIDQSNQETQIITQESIQLNHKISELQQ-LNQEKEKRI 1364 Query: 885 RTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKK 944 ++E Q Q ++ + ++ + H Q K EI + + Q+E I Sbjct: 1365 EQISKKAEEAIIQLQ-KEHQQKIEEVIH-------QSKGEILEGYNKQRAQLEQQIVFLN 1416 Query: 945 VLNEKYEKNIE-YVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDY 1003 NE+ +++ E + L+ + ++ K + EN L + + + K + Q+ Q+ + Sbjct: 1417 QQNEQTKQSFEKQIHSLQNEKEQQKISFENQKEQQRILFEQEKQQLAKQFESQKEQNKNA 1476 Query: 1004 TEQYINEIN-KLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQ-FTTKLENME 1061 E+ INE+N KLN+ + + EI A+N++ N V + ++ Q F+ +++ +E Sbjct: 1477 LEKQINELNEKLNSSKNKYESEIQAINKEYNK---KIQDTVEQTKIEMNQTFSQQIKKLE 1533 Query: 1062 EEMQRVSKQLLDSKQHNEELQILVR-EQDDQIKELKETKLTFEMNIPKTEGMIISSTIEP 1120 +++ +++Q + KQ+N ELQ ++ Q + +++++ K + + ++ + + E Sbjct: 1534 QQLNDLTRQNNEFKQNNNELQKQIQSNQVEAEQKVQQLKQNHQKQLDQSINQVTNEITES 1593 Query: 1121 MSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLET 1180 ++ + +F QE + L EQ L E Q L++ Sbjct: 1594 FKQQIATLEKQINLLKDTQAASSQNQTSKFTQEINSLSEQIVSLQQENQVLNQHKRDLDS 1653 Query: 1181 LNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAV-----DQRGFEI 1235 LN +L Q+ I +++ L Q N L S V + + + V ++ + + Sbjct: 1654 LNQKL-------QQNIQEIQENLNQSQKNNIKLESIVKDSQQKLEQQVKILEEEKERYSL 1706 Query: 1236 AELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSL 1295 E KQ + ++ + EL+ L F+ + VQ + Q++ N E + L Sbjct: 1707 IEKEKQSILEKNNQLENQMEELKRNLQQFKVQ-------VQQTEQKQEN-----EAFSKL 1754 Query: 1296 QNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKV--AFXXXXXXXXXXXXXXXXDLR 1353 QN+ D + +L + ++ NQI +L +++ + D Sbjct: 1755 QNENNDLVQQNNSLLFQINELNNQIHLLEDKLQKSSILQGKQITTENQQGEEIFDFEDFA 1814 Query: 1354 TENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVL--ELTHQLEL 1411 E + + +++S + +++ + S ND + + ++ Q ++ Sbjct: 1815 DELAASQNAKDKSRQDKEKKSEMVADSGKFKLNFASIQNNFDNDKDRMQIKRDMQQQQQI 1874 Query: 1412 KDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENAN 1471 K+ E + N E + + Q+++ + + + SEL M ++ N Sbjct: 1875 KNKEANDYFVDDDDDFDDSNQEKDKFKDQIIQEQGIAIEGQKNEISELKNQIDMMFQDIN 1934 Query: 1472 -HYETMQ-KESEIERVKLIEELN-VKITESVSLNKQVAELNKALEEEVAKTN-------- 1520 E +Q ES ++ K E+ N + I E + Q E +E+ A N Sbjct: 1935 SQREYIQYLESLVDEYKQKEQQNPLNINEFDNQGGQQQE--HFVEQSDASPNTKILNLKS 1992 Query: 1521 EMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDN 1574 ++ EN E EI+ LN ++ L+ ++ + I + A+D + R E+ +N Sbjct: 1993 KLADVQENHETEILNLNQQLIALKEEIKGLKNHIADLMQ-ANDDLELRIEEKEN 2045 Score = 149 bits (362), Expect = 5e-34 Identities = 283/1317 (21%), Positives = 578/1317 (43%), Gaps = 146/1317 (11%) Query: 360 SSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKL--EMVIQSL 417 + PS+ GS L S + ++ S + + SE L+ + + + KL + Q Sbjct: 420 NQPSRNGSQLASPNNFKSQLSISNQNF--MKSERLSPQQQQILPVSPTNKLLNASLGQGF 477 Query: 418 NKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNE 477 NKD D EYV+ E+ + ++AQL + H + +++ +++ Sbjct: 478 NKD--DFEYVLKEQVEYVRKKYLTHFVE--MLAQLGI----HTDN---LNLSNQSDEAPI 526 Query: 478 IAKVQEQLKQELNDEIKDVN-VKDLIEKLKSAEEQITQLNDEIDAANKNMIKV----KSN 532 I K++E+ ++ V++L +++++ E+++ + EID +IKV +SN Sbjct: 527 ILKLREEFQKIATKHTGYSQLVQELRQRIETKEKELIEKCSEIDNLKVKVIKVQEEAESN 586 Query: 533 HKL-KLKQMQ-------KTIDNFS----KVSDSNKEIVRLTEELHHLSQKVAELE----E 576 K+ KL++ Q K +S +V +EI EE K+ +LE E Sbjct: 587 PKIDKLEEQQRFRLIQHKFNSKYSFYKFRVQQFKQEIRAKNEEKKQAYSKIQQLEEINLE 646 Query: 577 EKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQK 636 + +L+L D D + D++ + ++N+ E I E + D + L L+Q Sbjct: 647 NERRERLYLEDLD---RLRDDLFMVLDNLKNILE-YFGIIDANEERNVD--RMLDTLRQY 700 Query: 637 YDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENL----KLDKEQL 692 ++ DK+ + D E K + +E+++ L E A I++L + K+QL Sbjct: 701 LEKQADKVFLHKNVFEDM---EKKIIDNQEEVEILKQQNGEFAKQIDDLEEINRTLKDQL 757 Query: 693 -YGTIKDLENDK-----EDIMNKLQN---YIQENMDLTDKLEKMSAEKISELLAKINHEE 743 ++K+ E DK D + +LQN +++N + EKM E E ++N Sbjct: 758 EIISLKNEEGDKLEQGIRDKIIQLQNENHILKKNQIAPELFEKMQQEN-REAQNELNERN 816 Query: 744 QSKIQTQF---GIDAKIQERDLYIENIESELSK------YKSRICRLEESIAVMEDRR-- 792 + I + ++ K+QE++ I+ I+SE+ + +++++ + E V + R Sbjct: 817 EVIINMKMEIQSLEQKLQEKEKQIKKIQSEMVEVEEEKIHQAKLVKSLEQFQVDKKARNE 876 Query: 793 ---------YSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDH-DRVVEKQLL 842 +++K ++ L+E+ K Y E I + + + D + ++K++ Sbjct: 877 EILEKVIEMEKIQKKLNKRNIELEEELKKYKETEINLEVQIEKAKKQGDEKTQDLQKKIK 936 Query: 843 EIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQ-TQLR 901 + E +N++ +K L E+ LQ +S++Q +K + ++ +S + QL Sbjct: 937 DFEKQNQQSNQKIGELKEQIATLQSQISNLQHELQQEKDKNIKQEMDFKKSNENDIAQLE 996 Query: 902 -DLESNLKRITHEHQTLI--VQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNI--EY 956 L+ +K + E + + + K E E I + E I ++K E NI + Sbjct: 997 FSLQKQIKNLQQEKEDAVNAERLKYEKEIQAIRRQDESEEYISEEKYQKLLSELNIKDQQ 1056 Query: 957 VTQLEAQLQEYKNNI-ENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYI-NEINKL 1014 V QL+ QLQE + + E+ E K++ +L + ++ Q + EQ I N +++ Sbjct: 1057 VKQLQQQLQEQEIALQESKEALYIERQKLDAQL-QEQLKNQSIELKKVNEQEIQNVVDQF 1115 Query: 1015 NALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLD- 1073 +LK K + + N A +E +L Q + + EEE+ R +K++++ Sbjct: 1116 EKILKDKAAQFEQEKSQKNEA----------FEKELKQIQNRFKEHEEEINRENKRVVEV 1165 Query: 1074 -------SKQHNEELQILVREQDDQIK--ELKETKLTFEMNIPKTEGMIISSTIEPMSDD 1124 K++NEELQ L ++ + ++K +++E +L E KT+ +I S S++ Sbjct: 1166 NQMELNGLKENNEELQSLNQKLEIELKQAQIRENELQSENENLKTKIELIESNAS--SEN 1223 Query: 1125 ANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKI-IQLETLNT 1183 V+ L + + E+++L E K+ T+L+E I ++ L Sbjct: 1224 KTIVNGLQTEKRQIEQNLSQAKRNLELSEKNIL-ELKQKI-TKLEEENESISLERSNLIK 1281 Query: 1184 ELTGH-DVVNQ-EQINQLK-SKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWK 1240 +L G+ D +N +Q NQ K S+L Q + D + + +++ S +DQ E + + Sbjct: 1282 QLQGNQDEINDVKQDNQQKQSELAQHIQQKDYYIQELENEITNLKSKIDQSNQETQIITQ 1341 Query: 1241 Q--HLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQ-- 1296 + L + ++ Q+ E ++ K E+ + +Q Q++ +++ + L+ Sbjct: 1342 ESIQLNHKISELQQLNQEKEKRIEQISKKAEEAIIQLQKEHQQKIEEVIHQSKGEILEGY 1401 Query: 1297 NKLQDKEE------HLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXX 1350 NK + + E + +N Q K + QI L++E E +K++F Sbjct: 1402 NKQRAQLEQQIVFLNQQNEQTKQS-FEKQIHSLQNEKEQQKISFENQKEQQRILFEQEKQ 1460 Query: 1351 DLRTENQSYKQMQEQSI-LNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTH-Q 1408 L + +S K+ + ++ INE N +L S N +E T + Sbjct: 1461 QLAKQFESQKEQNKNALEKQINELNEKLNSSKNKYESEIQAINKEYNKKIQDTVEQTKIE 1520 Query: 1409 LELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILR----L 1464 + S+ +K + LT++N+EF +Q E +K+I+ E E ++ L+ Sbjct: 1521 MNQTFSQQIKKLEQQLNDLTRQNNEF---KQNNNELQKQIQSNQVEAEQKVQQLKQNHQK 1577 Query: 1465 KMHENANHYETMQKESEIERVKLIE-ELN-VKITESVSLNKQVAELNK---ALEEEVAKT 1519 ++ ++ N ES +++ +E ++N +K T++ S Q ++ + +L E++ Sbjct: 1578 QLDQSINQVTNEITESFKQQIATLEKQINLLKDTQAASSQNQTSKFTQEINSLSEQIVSL 1637 Query: 1520 NEMQTALENQEIEIVTLNDE----ITNLQNMVRASSSKIQKHVSFASDTKQGRDEQL 1572 + L + ++ +LN + I +Q + S K S D++Q ++Q+ Sbjct: 1638 QQENQVLNQHKRDLDSLNQKLQQNIQEIQENLNQSQKNNIKLESIVKDSQQKLEQQV 1694 Score = 139 bits (337), Expect = 5e-31 Identities = 228/1165 (19%), Positives = 509/1165 (43%), Gaps = 96/1165 (8%) Query: 473 EDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQ--ITQLNDE--IDAANKNMIK 528 E++N + +E+L E D ++D ++ +++ LK+ E I N+E +D + + Sbjct: 641 EEINLENERRERLYLEDLDRLRD-DLFMVLDNLKNILEYFGIIDANEERNVDRMLDTLRQ 699 Query: 529 VKSNHKLKLKQMQKTIDNFSK-VSDSNKEIVRLTEELHHLSQKVAELEEEKGNL--QLHL 585 K+ + ++ K + D+ +E+ L ++ ++++ +LEE L QL + Sbjct: 700 YLEKQADKVFLHKNVFEDMEKKIIDNQEEVEILKQQNGEFAKQIDDLEEINRTLKDQLEI 759 Query: 586 VDY--DSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDK 643 + + G +E + K+I+++N E + + + + F+ +Q+ + ++ +E+ ++ Sbjct: 760 ISLKNEEGDKLEQGIRDKIIQLQN--ENHILKKNQIAPELFEKMQQEN--REAQNELNER 815 Query: 644 LADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDK 703 I ++ + E K E+QI + + E +E K+ + +L +++ + DK Sbjct: 816 NEVIINMKMEIQSLEQKLQEKEKQIKKIQSEMVE----VEEEKIHQAKLVKSLEQFQVDK 871 Query: 704 EDIMNKLQNYIQENMDLTDKLEKMSAEKISELL----AKINHEEQSKIQTQFGIDAKIQE 759 + ++ + E + KL K + E EL +IN E Q + + G D K Q+ Sbjct: 872 KARNEEILEKVIEMEKIQKKLNKRNIELEEELKKYKETEINLEVQIEKAKKQG-DEKTQD 930 Query: 760 RDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQ 819 I++ E + + +I L+E IA ++ + +L+ + Q EK K + Sbjct: 931 LQKKIKDFEKQNQQSNQKIGELKEQIATLQSQISNLQHELQQ------EKDKNIKQEMDF 984 Query: 820 EDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHY--- 876 + N +A L + ++KQ+ ++ E ++ ++ E+ I D + Y Sbjct: 985 KKSNENDIAQL---EFSLQKQIKNLQQEKEDAVNAERLKYEKEIQA-IRRQDESEEYISE 1040 Query: 877 NALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQI 936 + + ++ + + + Q QL++ E L+ + L ++++K L+ + Q+ Sbjct: 1041 EKYQKLLSELNIKDQQVKQLQQQLQEQEIALQE---SKEALYIERQK----LDAQLQEQL 1093 Query: 937 ESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQ 996 ++ + K +NE+ +N+ V Q E L++ E E + L+ I K+ Sbjct: 1094 KNQSIELKKVNEQEIQNV--VDQFEKILKDKAAQFEQEKSQKNEAFEKELKQIQNRF-KE 1150 Query: 997 QTQSPDYTEQYINEINKLNAL-LKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTT 1055 + + + + E+N++ LK+ +EE+ +LNQK+ ++ +S+ T Sbjct: 1151 HEEEINRENKRVVEVNQMELNGLKENNEELQSLNQKLEIELKQAQIRENELQSENENLKT 1210 Query: 1056 KLENMEEEMQRVSKQLL-----DSKQHNEELQILVRE---QDDQIKELKE--TKLTFEMN 1105 K+E +E +K ++ + +Q + L R + I ELK+ TKL E Sbjct: 1211 KIELIESNASSENKTIVNGLQTEKRQIEQNLSQAKRNLELSEKNILELKQKITKLEEENE 1270 Query: 1106 IPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQE-RSVLQEQSAKL 1164 E + ++ D+ N+V +Q+++ +IQE + + +K+ Sbjct: 1271 SISLERSNLIKQLQGNQDEINDVKQDNQQKQSELAQ-HIQQKDYYIQELENEITNLKSKI 1329 Query: 1165 NTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSK-LEQLNTENDN-LLSTVAELRS 1222 + QE T+II E++ H + +Q+NQ K K +EQ++ + + ++ E + Sbjct: 1330 DQSNQE--TQIITQESIQLN---HKISELQQLNQEKEKRIEQISKKAEEAIIQLQKEHQQ 1384 Query: 1223 SISSAVDQRGFEIAELWKQHLAQREADF-------QKTEHELRVQLSAFESKYEQLLDSV 1275 I + Q EI E + + AQ E ++T+ Q+ + +++ EQ + Sbjct: 1385 KIEEVIHQSKGEILEGYNKQRAQLEQQIVFLNQQNEQTKQSFEKQIHSLQNEKEQ--QKI 1442 Query: 1276 QSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQ-IEILRSEIEDEKVAF 1334 Q+E +I+ ++ L + + ++E +N EK + +N+ + +++ E E A Sbjct: 1443 SFENQKEQQRILFEQEKQQLAKQFESQKEQNKNALEKQINELNEKLNSSKNKYESEIQAI 1502 Query: 1335 XXXXXXXXXXXXXXXX-DL-RTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXX 1392 ++ +T +Q K++ EQ + ++ +N + K+++ Sbjct: 1503 NKEYNKKIQDTVEQTKIEMNQTFSQQIKKL-EQQLNDLTRQNNEFKQNNNELQKQIQSNQ 1561 Query: 1393 XRVNDAEAKVLEL--THQLELKDSEIYQKTHEYTITLTQRNDEFE---NVRQ--QLVEYE 1445 +AE KV +L HQ +L D I Q T+E T + Q+ E N+ + Q + Sbjct: 1562 V---EAEQKVQQLKQNHQKQL-DQSINQVTNEITESFKQQIATLEKQINLLKDTQAASSQ 1617 Query: 1446 KRIEDLTYEKES---ELAILRLK---MHENANHYETMQKESEIERVKLIEELNVKITESV 1499 + T E S ++ L+ + ++++ +++ ++ + ++ E LN ++ Sbjct: 1618 NQTSKFTQEINSLSEQIVSLQQENQVLNQHKRDLDSLNQKLQQNIQEIQENLNQSQKNNI 1677 Query: 1500 SLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVS 1559 L V + + LE++V E + E E ++ ++ L+N + +Q+ Sbjct: 1678 KLESIVKDSQQKLEQQVKILEEEKERYSLIEKEKQSILEKNNQLENQMEELKRNLQQFKV 1737 Query: 1560 FASDTKQGRDEQLDNTMNKELLDAV 1584 T+Q ++ + + + E D V Sbjct: 1738 QVQQTEQKQENEAFSKLQNENNDLV 1762 Score = 128 bits (308), Expect = 2e-27 Identities = 222/1104 (20%), Positives = 485/1104 (43%), Gaps = 109/1104 (9%) Query: 546 NFSKVSDSNKEIVRLTEELHHL-------SQKVAELEEEKGNLQLHLVDYDSGRMIESDV 598 N S SD I++L EE + SQ V EL + + L++ S E D Sbjct: 516 NLSNQSDEAPIILKLREEFQKIATKHTGYSQLVQELRQRIETKEKELIEKCS----EIDN 571 Query: 599 YK-KMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCS 657 K K+I+++ AE+ K L E Q+F L+Q H KY + ++ Q Sbjct: 572 LKVKVIKVQEEAESNPKIDKLEEQQRFRLIQ--HKFNSKYSFYKFRVQQFKQ-------- 621 Query: 658 EIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNY--IQ 715 EI++ + EE+ A S ++ + +EN + +E+LY ++DL+ ++D+ L N I Sbjct: 622 EIRAKN-EEKKQAYSKIQQLEEINLENER--RERLY--LEDLDRLRDDLFMVLDNLKNIL 676 Query: 716 ENMDLTDKLEKMSAEKISELLAKINHEEQSKI---QTQF-GIDAKIQERDLYIENIESEL 771 E + D E+ + +++ + L + ++ K+ + F ++ KI + +E ++ + Sbjct: 677 EYFGIIDANEERNVDRMLDTLRQYLEKQADKVFLHKNVFEDMEKKIIDNQEEVEILKQQN 736 Query: 772 SKYKSRICRLEESIAVMEDRRYSLERK---ADQLGSYLQEK--QKAYSEYTIQEDELV-- 824 ++ +I LEE ++D+ + K D+L +++K Q + ++++++ Sbjct: 737 GEFAKQIDDLEEINRTLKDQLEIISLKNEEGDKLEQGIRDKIIQLQNENHILKKNQIAPE 796 Query: 825 --------NRLA--VLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQ 874 NR A L + + V+ +EI+ ++LQ+K + +++ Q+ + + + + Sbjct: 797 LFEKMQQENREAQNELNERNEVIINMKMEIQSLEQKLQEKEK-QIKKIQSEMVEVEEEKI 855 Query: 875 HYNALVEKANRTDL-AESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFN 933 H LV+ + + ++ + + ++ ++E K++ ++ + ++ K+ ++ EI Sbjct: 856 HQAKLVKSLEQFQVDKKARNEEILEKVIEMEKIQKKL-NKRNIELEEELKKYKETEINLE 914 Query: 934 TQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKM--NLE-LID 990 QIE A KK +EK + + + E Q Q+ I L + L NL+ + Sbjct: 915 VQIEKA---KKQGDEKTQDLQKKIKDFEKQNQQSNQKIGELKEQIATLQSQISNLQHELQ 971 Query: 991 KHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKL 1050 + K Q D+ + N+I +L L+++ + + + NA+ + + ++ Sbjct: 972 QEKDKNIKQEMDFKKSNENDIAQLEFSLQKQIKNLQQEKEDAVNAE--RLKYEKEIQAIR 1029 Query: 1051 AQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNI-PKT 1109 Q ++ EE+ Q++ +L Q ++LQ ++EQ+ ++E KE + + Sbjct: 1030 RQDESEEYISEEKYQKLLSELNIKDQQVKQLQQQLQEQEIALQESKEALYIERQKLDAQL 1089 Query: 1110 EGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQ 1169 + + + +IE + + Q E+E Q+ +++ ++ + Sbjct: 1090 QEQLKNQSIELKKVNEQEIQNVVDQFEKILKDKAAQFEQEKSQKNEAFEKELKQIQNRFK 1149 Query: 1170 ECYTKIIQ-----LETLNTELTGHDVVNQEQINQLKSKLE-----------QLNTENDNL 1213 E +I + +E EL G N E++ L KLE +L +EN+N Sbjct: 1150 EHEEEINRENKRVVEVNQMELNGLK-ENNEELQSLNQKLEIELKQAQIRENELQSENEN- 1207 Query: 1214 LSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLD 1273 L T EL S +S+ ++ + K+ + Q + ++ + + K +L + Sbjct: 1208 LKTKIELIESNASSENKTIVNGLQTEKRQIEQNLSQAKRNLELSEKNILELKQKITKLEE 1267 Query: 1274 SVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVA 1333 +S + E +N I +Q+ Q+++ D ++ + Q + A I Q + E+E+E Sbjct: 1268 ENESISLERSNLI---KQLQGNQDEINDVKQDNQQKQSELAQHIQQKDYYIQELENEITN 1324 Query: 1334 FXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXX 1393 + N ++Q+ +N+E K+ Sbjct: 1325 LKSKIDQSNQETQIITQESIQLNHKISELQQ-----LNQEKE--KRIEQISKKAEEAIIQ 1377 Query: 1394 RVNDAEAKVLELTHQLELKDSEIYQK----THEYTITLTQRNDEF-ENVRQQL--VEYEK 1446 + + K+ E+ HQ + + E Y K + + L Q+N++ ++ +Q+ ++ EK Sbjct: 1378 LQKEHQQKIEEVIHQSKGEILEGYNKQRAQLEQQIVFLNQQNEQTKQSFEKQIHSLQNEK 1437 Query: 1447 RIEDLTYE--KESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVS-LNK 1503 + +++E KE + + + + A +E+ +++++ K I ELN K+ S + Sbjct: 1438 EQQKISFENQKEQQRILFEQEKQQLAKQFESQKEQNKNALEKQINELNEKLNSSKNKYES 1497 Query: 1504 QVAELNKALEEEVAKTNEMQTALE-----NQEIEIV--TLNDEITNLQNMVRASSSKIQK 1556 ++ +NK +++ T E QT +E +Q+I+ + LND +T N + +++++QK Sbjct: 1498 EIQAINKEYNKKIQDTVE-QTKIEMNQTFSQQIKKLEQQLND-LTRQNNEFKQNNNELQK 1555 Query: 1557 HVSFASDTKQGRDEQLDNTMNKEL 1580 + + + +QL K+L Sbjct: 1556 QIQSNQVEAEQKVQQLKQNHQKQL 1579 Score = 118 bits (284), Expect = 1e-24 Identities = 266/1506 (17%), Positives = 603/1506 (40%), Gaps = 139/1506 (9%) Query: 144 VTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXX 203 V L ++ + LS + +++ E IL+L++KI + +E +N++ + Sbjct: 1227 VNGLQTEKRQIEQNLSQAKRNLELSEKNILELKQKITK----LEEENESISLERSNLIKQ 1282 Query: 204 XXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEK-QRLLKDIESKDVRISSLEEANKLLEA 262 D KQ + Q +A + KD Q L +I + +I + +++ Sbjct: 1283 LQGNQDEINDVKQDNQQKQSE-LAQHIQQKDYYIQELENEITNLKSKIDQSNQETQIITQ 1341 Query: 263 ARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEI---EEKGS-LEI 318 +++ + S+L Q+L Q A ++ ++K E + KG LE Sbjct: 1342 ESIQLNHKISEL-QQLNQEKEKRIEQISKKAEEAIIQLQKEHQQKIEEVIHQSKGEILEG 1400 Query: 319 ANM--TELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGR 376 N +L ++I L N Q +Q+ ++ + L + K K+ ++ + + Sbjct: 1401 YNKQRAQLEQQIVFLNQQNEQTKQSFEKQIHSLQNEKEQQKISFENQKEQQRILFEQEKQ 1460 Query: 377 NTASKMKSPWSQLSSETLNQ--DTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTX 434 A + +S Q + Q + ++K+N ++ K E IQ++NK EY +DT Sbjct: 1461 QLAKQFESQKEQNKNALEKQINELNEKLNSSK-NKYESEIQAINK-----EYNKKIQDTV 1514 Query: 435 XXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIK 494 T Q++ QQ + T NE + +L++++ Sbjct: 1515 EQTKIEM---NQTFSQQIKKLEQQ---------LNDLTRQNNEFKQNNNELQKQIQSN-- 1560 Query: 495 DVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNF--SKVSD 552 V + +++LK ++ QL+ I+ ++ + K ++ ++K I+ ++ + Sbjct: 1561 QVEAEQKVQQLKQNHQK--QLDQSINQVTN---EITESFKQQIATLEKQINLLKDTQAAS 1615 Query: 553 SNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDS-GRMIESDVYKKMIEMENLAET 611 S + + T+E++ LS+++ L++E L H D DS + ++ ++ + + + Sbjct: 1616 SQNQTSKFTQEINSLSEQIVSLQQENQVLNQHKRDLDSLNQKLQQNIQEIQENLNQSQKN 1675 Query: 612 RLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDAL 671 +K S+++ + L Q++ IL+++ + S ++ ++ K+ LE Q++ L Sbjct: 1676 NIKLESIVKDSQQKLEQQVKILEEEKERY-------SLIEKEKQSILEKNNQLENQMEEL 1728 Query: 672 SASKKELALVIENLKLDKE-QLYGTIKDLENDKEDIMNKLQNYIQENMD----LTDKLEK 726 + ++ + ++ + +E + + +++ ND N L I E + L DKL+K Sbjct: 1729 KRNLQQFKVQVQQTEQKQENEAFSKLQNENNDLVQQNNSLLFQINELNNQIHLLEDKLQK 1788 Query: 727 MSAEKISELLAKINHEEQ---------SKIQTQFGIDAKIQERDLYIENIESELSKYKSR 777 S + ++ + E+ +Q D Q+++ E + ++ K+K Sbjct: 1789 SSILQGKQITTENQQGEEIFDFEDFADELAASQNAKDKSRQDKEKKSEMV-ADSGKFKLN 1847 Query: 778 ICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDH--DR 835 ++ + +DR ++ K D + Q K K ++Y + +D+ + D D+ Sbjct: 1848 FASIQNNFDNDKDR---MQIKRD-MQQQQQIKNKEANDYFVDDDDDFDDSNQEKDKFKDQ 1903 Query: 836 VVEKQLLEIEHENKELQK-KNQILL---------EENQNLQISLSDMQQHYNALVEKANR 885 ++++Q + IE + E+ + KNQI + E Q L+ + + +Q N Sbjct: 1904 IIQEQGIAIEGQKNEISELKNQIDMMFQDINSQREYIQYLESLVDEYKQKEQQNPLNINE 1963 Query: 886 TDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKV 945 D + ++ + D N K + + + VQ+ E E L + N Q+ + + K Sbjct: 1964 FDNQGGQQQEHFVEQSDASPNTKILNLKSKLADVQENHETEILNL--NQQLIALKEEIKG 2021 Query: 946 LNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEE-LNKMNLELIDKHVQKQQTQSPDYT 1004 L ++ LE +++E +N I L+ N ++ +N+ + ++ + +QK Q + Sbjct: 2022 LKNHIADLMQANDDLELRIEEKENQILQLHENQQDNVNEEQIGVLQEQIQKLQNKLRRQE 2081 Query: 1005 EQ--YINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEE 1062 E Y+ ++N+ L KQ DE + L K ++ +YE L Q K + ++ Sbjct: 2082 EDMAYLQQVNQ--NLNKQIDEYMKKLKMKQPGSESGQSKDDEEYEGGLVQQLGKTQQQQQ 2139 Query: 1063 EMQRVSKQLLDSK-QHNEEL-----QILVREQDDQIKELKETKLTFEMNIPKTEGMIISS 1116 + + +Q K Q ++L + + + Q ++++ + + +T Sbjct: 2140 QQPKQPQQQQSQKAQPQQQLQQQSKKDISQNQIGSYNDMQDQDFENDQDEEETYQSQKPK 2199 Query: 1117 TIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKII 1176 + + +++ + + IQ +Q Q + E + +++ Sbjct: 2200 ILNTQEAEQFQAQLINEKIQLQQQLAELKNDNDAIQTEDQIQIQQIQKRLEHNKKQLQLV 2259 Query: 1177 QLETLNTELTGHDVVN--------QEQINQLKSKLEQLNTENDNLLSTVAELRSSI---S 1225 Q N ++ +Q +LK + E L EN N + + +S S Sbjct: 2260 QEMASNRNKEKYEFAQLKEKHLHLTQQFKELKEETENLKLENQNYRNQLGSKNASPQINS 2319 Query: 1226 SAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNK 1285 D + + + L + + +L+ ++ +++ +++ + + Sbjct: 2320 MKPDSKNQSVTST--EQLDMLKLSLMDAQTQLKSMKDKYQKGIKRIKQMIEAPSFSASQP 2377 Query: 1286 IVTMEQVTSLQNKL----QDKEEHLR-NLQEKYADVINQIEILRSEIEDE-------KVA 1333 T E + +L ++L Q K + ++ LQ ++ I+ + + ED+ K Sbjct: 2378 AETEEDIVALADQLVASHQQKIQQIQLQLQHTLSEGISSHKSPQGNKEDDFVEENEGKTK 2437 Query: 1334 FXXXXXXXXXXXXXXXXDLRTE----NQSYKQMQEQSILNINEEN----AQLKKSSXXXX 1385 +L E N+ Q +Q+ ++ E Q Sbjct: 2438 ITDITSLKAYILYSQKLELIIEEALLNKMLAQNDQQNRKDLTSEQYEKVQQYLHILSDFQ 2497 Query: 1386 XXXXXXXXRVNDAEAKVLELTHQ---LELKDSEIYQKTHEYTITLTQRN----DEFENVR 1438 ND + K++ L + L+ DS + + ++ Q++ ++FEN++ Sbjct: 2498 QSLQEKEKEYNDMQDKLILLAEENEKLKKSDSSSNRNILQKPKSMQQKDPFQINDFENIQ 2557 Query: 1439 QQLVE-YEKRIEDLTYEKESELAILRLKMHENANHYE---TMQKESEIERVKLIEELNVK 1494 +++ + + ++ SE I L+ N + +MQ++S++++ + E+LN Sbjct: 2558 EEIPNPINNQGNESSFLSMSEQIIKELEGANNTKTPQQQVSMQQQSQVQK-QHEEDLNKL 2616 Query: 1495 ITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKI 1554 + E+ L +E + ++N E+ + L EI L+ A S K Sbjct: 2617 MKENSELKASKEYFASRQDELYDELRAKDEIIQNNELYVKNLKKEIRKLKESTEAVSQKE 2676 Query: 1555 QKHVSF 1560 Q + F Sbjct: 2677 QLKIIF 2682 Score = 98.7 bits (235), Expect = 1e-18 Identities = 179/903 (19%), Positives = 365/903 (40%), Gaps = 77/903 (8%) Query: 721 TDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICR 780 TD L + + ++ K+ E Q G +QE IE E EL + S I Sbjct: 512 TDNLNLSNQSDEAPIILKLREEFQKIATKHTGYSQLVQELRQRIETKEKELIEKCSEIDN 571 Query: 781 LEESIAVMEDRRYSLERKADQLGSY-----LQEK-QKAYSEYTIQEDELVNRLAVLMDHD 834 L+ + +++ S K D+L +Q K YS Y + + + + Sbjct: 572 LKVKVIKVQEEAES-NPKIDKLEEQQRFRLIQHKFNSKYSFYKFRVQQFKQEIRAKNEEK 630 Query: 835 RVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESEST 894 + ++ ++E N E +++ ++ LE+ L+ L + + ++E D E + Sbjct: 631 KQAYSKIQQLEEINLENERRERLYLEDLDRLRDDLFMVLDNLKNILEYFGIIDANEERNV 690 Query: 895 KYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNI 954 R L++ L++ + + K ED+E + E + K N ++ K I Sbjct: 691 D-----RMLDT-LRQYLEKQADKVFLHKNVFEDMEKKIIDNQEE-VEILKQQNGEFAKQI 743 Query: 955 EYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEI-NK 1013 + + ++ L K+ +E +++ EE +K+ + DK +Q Q Q E+ K Sbjct: 744 DDLEEINRTL---KDQLEIISLKNEEGDKLEQGIRDKIIQLQNENHILKKNQIAPELFEK 800 Query: 1014 LNALLKQKDEEIIALNQKINNAQVSYMSM---VSDYESKLAQFTTKLENMEEE---MQRV 1067 + ++ E+ N+ I N ++ S+ + + E ++ + +++ +EEE ++ Sbjct: 801 MQQENREAQNELNERNEVIINMKMEIQSLEQKLQEKEKQIKKIQSEMVEVEEEKIHQAKL 860 Query: 1068 SKQL----LDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSD 1123 K L +D K NEE+ V E + K+L + + E + K + I+ ++ + Sbjct: 861 VKSLEQFQVDKKARNEEILEKVIEMEKIQKKLNKRNIELEEELKKYKETEINLEVQ-IEK 919 Query: 1124 DANNVDXXXXXXXXXXXXLKVQEEE------EFIQERSVLQEQSAKLNTELQECYTKIIQ 1177 D + Q ++ E ++ + LQ Q + L ELQ+ K I+ Sbjct: 920 AKKQGDEKTQDLQKKIKDFEKQNQQSNQKIGELKEQIATLQSQISNLQHELQQEKDKNIK 979 Query: 1178 LETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAE 1237 E + +D+ E L+ +++ L E ++ ++ L+ +R E E Sbjct: 980 QEMDFKKSNENDIAQLEF--SLQKQIKNLQQEKEDAVNA-ERLKYEKEIQAIRRQDESEE 1036 Query: 1238 LWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDS-VQSSTQEETNKIVTMEQVTSLQ 1296 E +QK EL ++ + +QL + + +E I + LQ Sbjct: 1037 YIS------EEKYQKLLSELNIKDQQVKQLQQQLQEQEIALQESKEALYIERQKLDAQLQ 1090 Query: 1297 NKLQDKEEHLRNLQEK-YADVINQIE-ILR---SEIEDEKV----AFXXXXXXXXXXXXX 1347 +L+++ L+ + E+ +V++Q E IL+ ++ E EK AF Sbjct: 1091 EQLKNQSIELKKVNEQEIQNVVDQFEKILKDKAAQFEQEKSQKNEAFEKELKQIQNRFKE 1150 Query: 1348 XXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTH 1407 ++ EN+ ++ + + + E N +L+ + R N+ +++ L Sbjct: 1151 HEEEINRENKRVVEVNQMELNGLKENNEELQSLNQKLEIELKQAQIRENELQSENENLKT 1210 Query: 1408 QLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMH 1467 ++EL +S + E + E + Q L + ++ +E SE IL LK Sbjct: 1211 KIELIESNA---SSENKTIVNGLQTEKRQIEQNLSQAKRNLE------LSEKNILELK-- 1259 Query: 1468 ENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALE 1527 + E + +ER LI++L N+ E+N ++ K +E+ ++ Sbjct: 1260 QKITKLEEENESISLERSNLIKQLQG--------NQD--EINDVKQDNQQKQSELAQHIQ 1309 Query: 1528 NQEIEIVTLNDEITNLQNMVRASSSKIQ--KHVSFASDTKQGRDEQLDNTMNKELLDAVP 1585 ++ I L +EITNL++ + S+ + Q S + K +QL+ K + Sbjct: 1310 QKDYYIQELENEITNLKSKIDQSNQETQIITQESIQLNHKISELQQLNQEKEKRIEQISK 1369 Query: 1586 RAE 1588 +AE Sbjct: 1370 KAE 1372 Score = 69.7 bits (163), Expect = 6e-10 Identities = 107/564 (18%), Positives = 247/564 (43%), Gaps = 40/564 (7%) Query: 474 DVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAAN-KNMIKVKSN 532 D +E Q Q + LN + + LI + ++Q+ +L ++ DA ++ I+++ Sbjct: 2186 DQDEEETYQSQKPKILNTQEAEQFQAQLINEKIQLQQQLAELKNDNDAIQTEDQIQIQQI 2245 Query: 533 HKL---KLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYD 589 K KQ+Q + S + E +L E+ HL+Q+ EL+EE NL+L +Y Sbjct: 2246 QKRLEHNKKQLQLVQEMASNRNKEKYEFAQLKEKHLHLTQQFKELKEETENLKLENQNYR 2305 Query: 590 S---GRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLAD 646 + + + + +N + T + + +L+ D +L ++ KY + + Sbjct: 2306 NQLGSKNASPQINSMKPDSKNQSVTSTEQLDMLKLSLMDAQTQLKSMKDKY---QKGIKR 2362 Query: 647 ISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKD-LENDKED 705 I Q+ S + EE I AL + + +A + ++ + QL T+ + + + K Sbjct: 2363 IKQMIEAPSFSASQPAETEEDIVAL--ADQLVASHQQKIQQIQLQLQHTLSEGISSHKSP 2420 Query: 706 IMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIE 765 NK ++++EN K I+ L A I + ++ ++ + + K+ ++ Sbjct: 2421 QGNKEDDFVEENEG------KTKITDITSLKAYILYSQKLELIIEEALLNKMLAQNDQQN 2474 Query: 766 NIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYT--IQEDEL 823 + +Y+ ++++ + ++ D + SL+ K + +Q+K +E +++ + Sbjct: 2475 RKDLTSEQYE----KVQQYLHILSDFQQSLQEKEKEYND-MQDKLILLAEENEKLKKSDS 2529 Query: 824 VNRLAVLMDHDRVVEKQLLEI-EHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEK 882 + +L + +K +I + EN + + N I NQ + S M + +E Sbjct: 2530 SSNRNILQKPKSMQQKDPFQINDFENIQEEIPNPI---NNQGNESSFLSMSEQIIKELEG 2586 Query: 883 ANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRD 942 AN T + + + Q +S +++ E ++++ E++ + F ++ + + Sbjct: 2587 ANNTKTPQQQVSMQQ------QSQVQKQHEEDLNKLMKENSELKASKEYFASRQDELYDE 2640 Query: 943 KKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPD 1002 + +E + N YV L+ ++++ K + E ++ E+L + ++ I K++ D Sbjct: 2641 LRAKDEIIQNNELYVKNLKKEIRKLKESTEAVSQK-EQLKIIFIKFIQAMADKKKQLEAD 2699 Query: 1003 YTEQYINEINKLNALLKQKDEEII 1026 ++ + + + Q EEII Sbjct: 2700 ---NFLAILFSMLGVTDQDKEEII 2720 >UniRef50_A0CKK3 Cluster: Chromosome undetermined scaffold_2, whole genome shotgun sequence; n=1; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_2, whole genome shotgun sequence - Paramecium tetraurelia Length = 2413 Score = 170 bits (413), Expect = 3e-40 Identities = 289/1403 (20%), Positives = 595/1403 (42%), Gaps = 120/1403 (8%) Query: 234 DEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXX 293 D+ Q ++K ++ + ++ LEE + L ++L +L E+E+ Sbjct: 728 DQNQDIIKLVKQELKKLKKLEEEYQQLRQINSNLTLAQEELNLEIEEKNQLLEQN----- 782 Query: 294 XLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQI---RQTNKELENKLA 350 KQ +E +E+ + K +LE+ + K +E+ + L QI +Q KE + KL Sbjct: 783 ---KQQLEIE-QEQLQNAIKENLELKQQNQTQKLLEVNKQLELQIEGLKQKEKEQQAKLE 838 Query: 351 TMGTESKAVSSPSKKGSPLISRKSGR-NTASKMKSPWSQLSSETLNQDTDKKINKNEIAK 409 ++ T+++ + LI + + + N+ S++ S ++ L Q +K E+ K Sbjct: 839 SLKTQTENQDKKLIQNQNLIQQLNDKENSHSQLNSQLQSDVNDYLKQIQEK---SQEVEK 895 Query: 410 LEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVG 469 +M + S + +E + +E Q+Q E QQ+++ + Sbjct: 896 FKMDLLSSENRVRQQELIANELKNEIMLLTNENNNHKAQQQQIQ-ELQQNLQ----TQIN 950 Query: 470 TNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKV 529 N + + I K++E L Q LN +I K + + Q +N + D +I Sbjct: 951 LNQDQLVSIQKLKEDLNQ-LNQQI--------TYKSEQLDSQSMDINQQKDLLQLQIISQ 1001 Query: 530 KSNHKLKLKQMQKTI-DNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDY 588 ++ +LKQ+Q+ I +N + +++ +K++ +++L L + ++E EKG +L Sbjct: 1002 QN----QLKQLQQQIVENETVITEQSKKLNETSQDLEKLKFDLNQVEIEKG--KLFQQQE 1055 Query: 589 DSGRMIESDVYKKMIEMENLAETRLK-AISLLESQKFDLVQELHILQQKYDEVEDKLADI 647 DS I+ D+ +K IE +LK I E + D + EL I Q++ +E+ K Sbjct: 1056 DSLIQIK-DLLQK-IEQGEQHNLKLKDQIEQQEQRLQDNIAELQIKQEEINEMAMK-EQA 1112 Query: 648 SQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIM 707 S+ + D C + K + E QI+ +++L N ++ ++DL+ + E++ Sbjct: 1113 SKFELD--CLKAKCLSYELQIE----DQEKLISQQNNQAQQLSEIQEQLQDLQKNNEELQ 1166 Query: 708 NKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENI 767 L N ++N D+ ++ K N EE+ + + Q + IQ RDL I Sbjct: 1167 QNL-NDKEQNYDILQNAYYDIGDQ------KKNLEEEIEDKNQ---EISIQNRDLKI--Y 1214 Query: 768 ESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTI-QEDELVNR 826 + ++ + K+ I +L+E IA + + +L +Q +K Y I + L R Sbjct: 1215 KEQIDQNKALINQLQEQIAQFRNSANINFAENCKLNEQVQMMKKELESYQIDSKQNLDER 1274 Query: 827 LAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQ---ISLSDMQQHYNALVEKA 883 + D ++ + E+E++ ++Q K+ + E N NLQ +L D++Q + Sbjct: 1275 SDKIKDLEQQIIDLQNELENQQFQIQYKDSKIEELNNNLQETSENLDDIKQELEITSRQL 1334 Query: 884 NRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDK 943 + E K + Q LE +++ E Q I+ ++ E+L N IE + Sbjct: 1335 KNEQAQKEEELKCKQQ---LEGIIQQQKLEAQQYILTTNQQQENLLSLHNKIIEYCNEIE 1391 Query: 944 KVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDY 1003 + N+ IE Q + +++ N+ N +E+ K NLE + + QTQS + Sbjct: 1392 SLKNQISTLQIECEKQ-QKEMEVLNENLNQANTLLED-QKSNLENSEFQINYFQTQSKEI 1449 Query: 1004 TEQY------INEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKL 1057 QY + ++ + N +L + ++I N + +S + LA + Sbjct: 1450 KIQYDQLQEKLQDLEQENEILNRNQSNNAQKQEQIQNEKYILQQEISQLKQSLATLFEER 1509 Query: 1058 ENMEEEMQR----VSKQLLDSKQHNEELQILVREQDD---QIKELKETKLTFEMNIP--- 1107 +N ++ +Q + Q + + +++++++ ++ D ++ EL+E T++ NI Sbjct: 1510 QNNQDRIQELIFTIELQKSEDAKKDQKIELITNQELDLQQRLIELQEQNTTYQQNIESIQ 1569 Query: 1108 ---KTEGMIISSTIEPMSDDANNVD--XXXXXXXXXXXXLKVQEEEEFIQERSV-LQEQS 1161 K E +I + + D +D + ++E+ F+++ + E S Sbjct: 1570 NQLKDEQLITENLKQQNEKDQKQIDELKNIEIVQLNQQIVNLKEKIAFLEQNEIQTSELS 1629 Query: 1162 AKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELR 1221 + L QE K Q E L E +D + +E+IN K+++ QL +N +L+ Sbjct: 1630 SHLENLRQEKQIK-EQKEKLFRE--ENDKL-KEEINNFKNQINQLERDNITNEQNYHQLQ 1685 Query: 1222 SSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQE 1281 + + + +E + +Q L Q D + L+V + FE K EQL + ++ +E Sbjct: 1686 EEMKTI--EIKYEQLKTQEQQLIQLNQDKSEQISNLKVIQTDFEQKLEQLNNEIKVYQEE 1743 Query: 1282 ETNKIVTMEQVTSLQNKLQDKEE----HLRNLQEKYADVINQIEI---LRSEIEDEKVAF 1334 + + + Q+ LQ +L+++ E L L E+ D+ Q EI ++E D+ Sbjct: 1744 KQTQENKISQLNELQLQLENQRESITLELEQLNEQIKDLKKQSEINACQQNEKIDQLTNQ 1803 Query: 1335 XXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNIN----------EENAQLKKSSXXX 1384 +L +N+ + Q Q + + EN QL++ Sbjct: 1804 ITLLQQKNEEQENQIKELSLQNEELQDQQLQFMEQLQTEKQAHNTQLSENYQLQEKLQNE 1863 Query: 1385 XXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEF-ENVRQQLVE 1443 +V E ++ +L L KD + + + + +N++ ++ + ++ Sbjct: 1864 LENAQQSKDQVQRLEQELYQLQQALLDKDESLVRWREQQCCSQYIQNEQIGQSQNTEQID 1923 Query: 1444 YEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNK 1503 E E K L + + N Y+ KE R+ +E T+ ++ Sbjct: 1924 KENNNESEKLNKGIMQESLSNPLEDQDNDYKVEMKEHVNSRIFDLEFDEKSGTQQQNILP 1983 Query: 1504 QVAE-LNKALEEEVAKTNEMQTALENQEIEIVT--LNDEITNL--QNMVRASSSKIQKHV 1558 V+E +++A + + ++ + Q+++ L +I NL +N++ S S+ + + Sbjct: 1984 AVSENVSEAYDLAIKRSMGLSKDQIIQQLQDQNRLLQQQIENLNQENIIYESPSQHKALI 2043 Query: 1559 -SFASDTKQGRDEQLDNTMNKEL 1580 +Q +++QL + L Sbjct: 2044 EELQQQIQQLKNQQLQRIIQSPL 2066 Score = 168 bits (408), Expect = 1e-39 Identities = 312/1504 (20%), Positives = 658/1504 (43%), Gaps = 140/1504 (9%) Query: 152 KEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXX 211 +E N L V++ ++ I L ++I+++++++ N+ Sbjct: 413 QELQNLNDQLNVQIIKQQSQIQLLHKQIDDQNKVMMT-NEKIIQQYQQKEKQLYEELDNQ 471 Query: 212 EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271 +D ++++ K++ + I++ ++K LL++IE I S + E + + Sbjct: 472 KDQQEEINKLKISLISLN----NQKDHLLENIEQLQNEIISKNDVINQAENQINQQVRQL 527 Query: 272 SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTK-KIEL 330 +K Q+L + L ++ + +I + +I N EL K + E Sbjct: 528 NKGQQDLIKYENYNEELQQRNKILQERLKKAEDNNLQQILQDKLQDINNKLELLKNENES 587 Query: 331 LEHLNCQIRQTNKE--LENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQ 388 L H Q+ Q K+ E + + + + S+ ISR+S + S + Sbjct: 588 LSH-QIQVLQDEKDKYFEQLIQLIKQKQNNLLYKSQSPKNAISRQSSKFGDQLFISDGNN 646 Query: 389 LSSETLNQDTDK--KINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKD 446 + DK +I +KL V Q N D + ++++ + Sbjct: 647 KQISKFQTELDKFDEIISQITSKLIQVEQQKN-DFRNLNLEQQKQNSQYLLQISNLEQDN 705 Query: 447 TLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLK 506 +Q+ + Q M G +++ N +D+ ++ K + + ++L +E + + + + L Sbjct: 706 KKYSQMLQQWHQQMTGNISVNLDQN-QDIIKLVKQELKKLKKLEEEYQQL--RQINSNLT 762 Query: 507 SAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHH 566 A+E+ LN EI+ N+ + + K +++ +Q+Q I ++ N + +L E Sbjct: 763 LAQEE---LNLEIEEKNQLLEQNKQQLEIEQEQLQNAIKENLELKQQN-QTQKLLEVNKQ 818 Query: 567 LSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAET---RLKAISLLESQ- 622 L ++ L++++ Q L +S + + KK+I+ +NL + + + S L SQ Sbjct: 819 LELQIEGLKQKEKEQQAKL---ESLKTQTENQDKKLIQNQNLIQQLNDKENSHSQLNSQL 875 Query: 623 KFDLVQELHILQQKYDEVE----DKLADISQL-QSDQVCSEIKS--VHLEEQIDALSASK 675 + D+ L +Q+K EVE D L+ +++ Q + + +E+K+ + L + + A + Sbjct: 876 QSDVNDYLKQIQEKSQEVEKFKMDLLSSENRVRQQELIANELKNEIMLLTNENNNHKAQQ 935 Query: 676 KELALVIENLK----LDKEQLYGTIK---DLENDKEDIMNKLQNYIQENMDLTDKLEKMS 728 +++ + +NL+ L+++QL K DL + I K + ++MD+ + + + Sbjct: 936 QQIQELQQNLQTQINLNQDQLVSIQKLKEDLNQLNQQITYKSEQLDSQSMDINQQKDLLQ 995 Query: 729 AEKISELLAKINHEEQSKIQTQFGI---DAKIQERDLYIENIESELSKYKSRICRL---- 781 + IS+ ++ +Q ++ + I K+ E +E ++ +L++ + +L Sbjct: 996 LQIISQQ-NQLKQLQQQIVENETVITEQSKKLNETSQDLEKLKFDLNQVEIEKGKLFQQQ 1054 Query: 782 EESIAVMEDRRYSLE-------RKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHD 834 E+S+ ++D +E + DQ+ Q Q +E I+++E +N +A + + Sbjct: 1055 EDSLIQIKDLLQKIEQGEQHNLKLKDQIEQQEQRLQDNIAELQIKQEE-INEMA-MKEQA 1112 Query: 835 RVVEKQLLEIEHENKELQKKNQILLEENQNLQIS-LSDMQQHYNALVEKANRTDLAESES 893 E L+ + + ELQ ++Q L QN Q LS++Q+ L + + Sbjct: 1113 SKFELDCLKAKCLSYELQIEDQEKLISQQNNQAQQLSEIQEQLQDL----------QKNN 1162 Query: 894 TKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKN 953 + Q L D E N + + + + QKK E++E + N +I RD K+ E+ ++N Sbjct: 1163 EELQQNLNDKEQNYDILQNAYYDIGDQKKNLEEEIE-DKNQEISIQNRDLKIYKEQIDQN 1221 Query: 954 IEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINK 1013 + QL+ Q+ +++N+ N+N E K+N + VQ + + Y +++ Sbjct: 1222 KALINQLQEQIAQFRNSA---NINFAENCKLN-----EQVQMMKKELESYQIDSKQNLDE 1273 Query: 1014 LNALLKQKDEEIIALNQKINNAQ--VSYM-SMVSDYESKLAQFTTKLENMEEEMQRVSKQ 1070 + +K +++II L ++ N Q + Y S + + + L + + L+++++E++ S+Q Sbjct: 1274 RSDKIKDLEQQIIDLQNELENQQFQIQYKDSKIEELNNNLQETSENLDDIKQELEITSRQ 1333 Query: 1071 LLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMI--ISSTIEPMSDDANNV 1128 L + + EE ++ ++Q + I +++ KL + I T + S + + N + Sbjct: 1334 LKNEQAQKEE-ELKCKQQLEGI--IQQQKLEAQQYILTTNQQQENLLSLHNKIIEYCNEI 1390 Query: 1129 DXXXXXXXXXXXXLKVQEEEEFI------QERSVLQEQSAKL-NTELQECYTKI------ 1175 + + Q++E + Q ++L++Q + L N+E Q Y + Sbjct: 1391 ESLKNQISTLQIECEKQQKEMEVLNENLNQANTLLEDQKSNLENSEFQINYFQTQSKEIK 1450 Query: 1176 IQLETLNTELTG----HDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQR 1231 IQ + L +L ++++N+ Q N + K EQ+ E L +++L+ S+++ ++R Sbjct: 1451 IQYDQLQEKLQDLEQENEILNRNQSNNAQ-KQEQIQNEKYILQQEISQLKQSLATLFEER 1509 Query: 1232 GFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQ 1291 + Q L + QK+E + Q E Q LD Q + + + Sbjct: 1510 QNNQDRI--QELIFT-IELQKSEDAKKDQ--KIELITNQELDLQQRLIELQEQNTTYQQN 1564 Query: 1292 VTSLQNKLQDKEEHLRNLQE------KYADVINQIEI--LRSEIED--EKVAFXXXXXXX 1341 + S+QN+L+D++ NL++ K D + IEI L +I + EK+AF Sbjct: 1565 IESIQNQLKDEQLITENLKQQNEKDQKQIDELKNIEIVQLNQQIVNLKEKIAFLEQNEIQ 1624 Query: 1342 XXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAK 1401 +LR E KQ++EQ EEN +LK+ E Sbjct: 1625 TSELSSHLENLRQE----KQIKEQKEKLFREENDKLKEEINNFKNQINQLERDNITNEQN 1680 Query: 1402 VLELTHQLELKDSEIYQ-KTHEYT-ITLTQ-RNDEFENVRQQLVEYEKRIEDLTYEKESE 1458 +L +++ + + Q KT E I L Q ++++ N++ ++E+++E L E Sbjct: 1681 YHQLQEEMKTIEIKYEQLKTQEQQLIQLNQDKSEQISNLKVIQTDFEQKLEQLNNE---- 1736 Query: 1459 LAILRLKMHENANHYETMQKESEIERVKL-IEELNVKIT-ESVSLNKQVAELNKALEEEV 1516 +K+++ + K S++ ++L +E IT E LN+Q+ +L K E Sbjct: 1737 -----IKVYQEEKQTQE-NKISQLNELQLQLENQRESITLELEQLNEQIKDLKKQSEINA 1790 Query: 1517 AKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQ-KHVSFASDTKQGRDEQLDNT 1575 + NE L NQ + N+E N + + ++Q + + F + ++Q NT Sbjct: 1791 CQQNEKIDQLTNQITLLQQKNEEQENQIKELSLQNEELQDQQLQFMEQLQ--TEKQAHNT 1848 Query: 1576 MNKE 1579 E Sbjct: 1849 QLSE 1852 Score = 156 bits (379), Expect = 4e-36 Identities = 250/1288 (19%), Positives = 554/1288 (43%), Gaps = 122/1288 (9%) Query: 344 ELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQ--LSSETLNQDTDKK 401 E++N LA + E +P K+ S + +N K+ S L E LN + Sbjct: 256 EVKNILAFIAREKSRFETPKKQNSQHEQIDNIQNEHQKLVSLHENVMLQIEKLNYQVSQC 315 Query: 402 INKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHME 461 + ++ + + I+ L+++L KE + KD + QLQ + ++ + Sbjct: 316 LQTSQYGQKD-TIKELSQNL--KEMI-----NQFSLSKNTLKDKDQKLIQLQNDLMKYKK 367 Query: 462 GPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDA 521 L+ N +D++ +Q + +L + + L+ + K EE +L + D Sbjct: 368 ---LVE---NKKDIDTQKYIQVINELKLESSNLEKKYQQLVIQEKFGEENNQELQNLNDQ 421 Query: 522 ANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNL 581 N +IK +S +L + K ID+ +KV +N++I++ QK +L EE Sbjct: 422 LNVQIIKQQSQIQL----LHKQIDDQNKVMMTNEKIIQ------QYQQKEKQLYEE---- 467 Query: 582 QLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVE 641 D+ + + ++ K I + +L + + +E + +++ + ++ Q +++ Sbjct: 468 ------LDNQKDQQEEINKLKISLISLNNQKDHLLENIEQLQNEIISKNDVINQAENQIN 521 Query: 642 DKLADISQLQSDQVCSEIKSVHLEEQIDALSAS-KKELALVIENLKLDKEQ-LYGTIKDL 699 ++ +++ Q D + E + L+++ L KK ++ + DK Q + ++ L Sbjct: 522 QQVRQLNKGQQDLIKYENYNEELQQRNKILQERLKKAEDNNLQQILQDKLQDINNKLELL 581 Query: 700 ENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQE 759 +N+ E + +++Q E ++L ++ +K + LL K + ++ I Q +K + Sbjct: 582 KNENESLSHQIQVLQDEKDKYFEQLIQLIKQKQNNLLYK-SQSPKNAISRQ---SSKFGD 637 Query: 760 RDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQ 819 + + ++SK+++ + + +E I+ + + +E++ + + E+QK S+Y +Q Sbjct: 638 QLFISDGNNKQISKFQTELDKFDEIISQITSKLIQVEQQKNDFRNLNLEQQKQNSQYLLQ 697 Query: 820 EDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNAL 879 L + D Q+L+ H+ + N+ ++L Q + Sbjct: 698 ISNL--------EQDNKKYSQMLQQWHQ------------QMTGNISVNLDQNQDIIKLV 737 Query: 880 VEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEI-----EDLEIEFNT 934 ++ + E E YQ QLR + SNL + E L +++K ++ + LEIE Sbjct: 738 KQELKKLKKLEEE---YQ-QLRQINSNL-TLAQEELNLEIEEKNQLLEQNKQQLEIE-QE 791 Query: 935 QIESAIRDKKVLNE--KYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKH 992 Q+++AI++ L + + +K +E QLE Q++ K + +E L K E DK Sbjct: 792 QLQNAIKENLELKQQNQTQKLLEVNKQLELQIEGLKQKEKEQQAKLESL-KTQTENQDKK 850 Query: 993 VQKQQTQSPDYTEQYINEINKLNALLKQK-DEEIIALNQKINNAQVSYMSMVSDYESKLA 1051 + + Q ++ N ++LN+ L+ ++ + + +K + M ++S E+++ Sbjct: 851 LIQNQNLIQQLNDKE-NSHSQLNSQLQSDVNDYLKQIQEKSQEVEKFKMDLLSS-ENRVR 908 Query: 1052 QFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKE-----TKLTFEMNI 1106 Q ++ E+ ++ + + K +++Q L + QI ++ KL ++N Sbjct: 909 QQELIANELKNEIMLLTNENNNHKAQQQQIQELQQNLQTQINLNQDQLVSIQKLKEDLNQ 968 Query: 1107 PKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLN- 1165 + S ++ S D N Q +++ ++ +V+ EQS KLN Sbjct: 969 LNQQITYKSEQLDSQSMDINQQKDLLQLQIISQQNQLKQLQQQIVENETVITEQSKKLNE 1028 Query: 1166 --TELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSS 1223 +L++ + Q+E +L + QI L K+EQ N L + + Sbjct: 1029 TSQDLEKLKFDLNQVEIEKGKLFQQQEDSLIQIKDLLQKIEQGEQHNLKLKDQIEQQEQR 1088 Query: 1224 ISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEET 1283 + + + + E+ +A +E Q ++ EL L A YE ++ + ++ Sbjct: 1089 LQDNIAELQIKQEEI--NEMAMKE---QASKFELDC-LKAKCLSYELQIEDQEKLISQQN 1142 Query: 1284 NKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRS---EIEDEKVAFXXXXXX 1340 N+ +Q++ +Q +LQD +++ LQ+ D +IL++ +I D+K Sbjct: 1143 NQ---AQQLSEIQEQLQDLQKNNEELQQNLNDKEQNYDILQNAYYDIGDQKKNLEEEIED 1199 Query: 1341 XXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEA 1400 DL+ YK+ +Q+ IN+ Q+ + +N AE Sbjct: 1200 KNQEISIQNRDLKI----YKEQIDQNKALINQLQEQIAQ---------FRNSANINFAEN 1246 Query: 1401 KVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYE---KES 1457 L Q+ K+ E YQ + L +R+D+ +++ QQ+++ + +E+ ++ K+S Sbjct: 1247 CKLNEQVQMMKKELESYQIDSKQ--NLDERSDKIKDLEQQIIDLQNELENQQFQIQYKDS 1304 Query: 1458 ELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITE---SVSLNKQVAELNKALEE 1514 ++ L + E + + + +++E EI +L E K E L + + ++ Sbjct: 1305 KIEELNNNLQETSENLDDIKQELEITSRQLKNEQAQKEEELKCKQQLEGIIQQQKLEAQQ 1364 Query: 1515 EVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDN 1574 + TN+ Q L + +I+ +EI +L+N + + +K + ++ N Sbjct: 1365 YILTTNQQQENLLSLHNKIIEYCNEIESLKNQISTLQIECEKQQKEMEVLNENLNQA--N 1422 Query: 1575 TMNKELLDAVPRAELDLAMYMLHQRDVR 1602 T+ ++ + +E + + ++++ Sbjct: 1423 TLLEDQKSNLENSEFQINYFQTQSKEIK 1450 Score = 151 bits (365), Expect = 2e-34 Identities = 279/1424 (19%), Positives = 595/1424 (41%), Gaps = 125/1424 (8%) Query: 151 IKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKN---KATTXXXXXXXXXXXXX 207 I + N L LQ ++ ET I + +K+NE Q +E Sbjct: 998 IISQQNQLKQLQQQIVENETVITEQSKKLNETSQDLEKLKFDLNQVEIEKGKLFQQQEDS 1057 Query: 208 XXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEI 267 +D Q++ + +++ + ++ + + ++QRL +I ++ + E +A++FE+ Sbjct: 1058 LIQIKDLLQKIEQGEQHNLKLKDQIEQQEQRLQDNIAELQIKQEEINEMAMKEQASKFEL 1117 Query: 268 SLEHSK-LAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIA-NMTELT 325 +K L+ EL+ A+Q E +E+ + +K + E+ N+ + Sbjct: 1118 DCLKAKCLSYELQ--IEDQEKLISQQNNQAQQLSE--IQEQLQDLQKNNEELQQNLNDKE 1173 Query: 326 KKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSP 385 + ++L++ I K LE ++ E +S ++ K + + K+ Sbjct: 1174 QNYDILQNAYYDIGDQKKNLEEEIEDKNQE---ISIQNR------DLKIYKEQIDQNKAL 1224 Query: 386 WSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGK 445 +QL + IN E KL +Q + K+L + Y I K + Sbjct: 1225 INQLQEQIAQFRNSANINFAENCKLNEQVQMMKKEL--ESYQIDSKQNLDERSDKIKDLE 1282 Query: 446 DTLI-AQLQLEHQQHME----------GPSLIHVGTNTEDVN-EIAKVQEQLKQELNDEI 493 +I Q +LE+QQ +L N +D+ E+ QLK E + Sbjct: 1283 QQIIDLQNELENQQFQIQYKDSKIEELNNNLQETSENLDDIKQELEITSRQLKNEQAQKE 1342 Query: 494 KDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDS 553 +++ K +E + ++Q + I N+ + S H ++ + +++S Sbjct: 1343 EELKCKQQLEGI--IQQQKLEAQQYILTTNQQQENLLSLHNKIIEYCNEIESLKNQISTL 1400 Query: 554 NKEIVRLTEELHHLSQKVAE----LEEEKGNL-----QLHLVDYDSGRM-IESD-VYKKM 602 E + +E+ L++ + + LE++K NL Q++ S + I+ D + +K+ Sbjct: 1401 QIECEKQQKEMEVLNENLNQANTLLEDQKSNLENSEFQINYFQTQSKEIKIQYDQLQEKL 1460 Query: 603 IEMENLAETRLKAISLLESQKFDLVQ-ELHILQQKYDEVEDKLADI---SQLQSDQVCSE 658 ++E E L +QK + +Q E +ILQQ+ +++ LA + Q D++ Sbjct: 1461 QDLEQENEI-LNRNQSNNAQKQEQIQNEKYILQQEISQLKQSLATLFEERQNNQDRIQEL 1519 Query: 659 IKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENM 718 I ++ L++ DA K EL I N +LD +Q +++ + + +QN +++ Sbjct: 1520 IFTIELQKSEDAKKDQKIEL---ITNQELDLQQRLIELQEQNTTYQQNIESIQNQLKDEQ 1576 Query: 719 DLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRI 778 +T+ L++ + EK + + ++ + E ++ Q ++E+ ++E E + S+ S + Sbjct: 1577 LITENLKQQN-EKDQKQIDELKNIEIVQLNQQI---VNLKEKIAFLEQNEIQTSELSSHL 1632 Query: 779 CRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVE 838 L + + E + + D+L + + ++ ++ D + N H E Sbjct: 1633 ENLRQEKQIKEQKEKLFREENDKLKEEINNFKNQINQ--LERDNITNEQNY---HQLQEE 1687 Query: 839 KQLLEIEHENKELQKKNQILLEENQNLQIS-LSDMQQHYNALVEKANRTDLAESESTKYQ 897 + +EI++E + Q++ I L ++++ QIS L +Q + +E+ N +E YQ Sbjct: 1688 MKTIEIKYEQLKTQEQQLIQLNQDKSEQISNLKVIQTDFEQKLEQLN------NEIKVYQ 1741 Query: 898 TQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIE-FNTQIESAIRDKKV----LNEKYEK 952 + + E+ + ++ +E Q L ++ ++E LE+E N QI+ + ++ NEK ++ Sbjct: 1742 EEKQTQENKISQL-NELQ-LQLENQRESITLELEQLNEQIKDLKKQSEINACQQNEKIDQ 1799 Query: 953 NIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEIN 1012 +T L+ + +E +N I+ L++ EEL L+ +++ ++Q + +E Y + Sbjct: 1800 LTNQITLLQQKNEEQENQIKELSLQNEELQDQQLQFMEQLQTEKQAHNTQLSENYQLQEK 1859 Query: 1013 KLNAL--LKQKDEEIIALNQKINNAQVSYMSM-VSDYESKLAQFTTKLENMEEEMQRVSK 1069 N L +Q +++ L Q++ Q + + S + Q ++ E+ Q + Sbjct: 1860 LQNELENAQQSKDQVQRLEQELYQLQQALLDKDESLVRWREQQCCSQYIQNEQIGQSQNT 1919 Query: 1070 QLLDSKQHNEELQI---LVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDAN 1126 + +D + +NE ++ +++E E ++ EM + E Sbjct: 1920 EQIDKENNNESEKLNKGIMQESLSNPLEDQDNDYKVEMKEHVNSRIFDLEFDEKSGTQQQ 1979 Query: 1127 NVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELT 1186 N+ L ++ +++ + Q Q N LQ+ Q+E LN E Sbjct: 1980 NILPAVSENVSEAYDLAIKRSMGLSKDQIIQQLQDQ--NRLLQQ------QIENLNQENI 2031 Query: 1187 GHDVVNQEQ--INQLKSKLEQLNTENDNLLSTV-AELRSSISSAVDQRGFEIAELWKQHL 1243 ++ +Q + I +L+ +++QL +N L + + L+ I +D E+ + K HL Sbjct: 2032 IYESPSQHKALIEELQQQIQQL--KNQQLQRIIQSPLQVLIGEHLDDEKDELNQQEKYHL 2089 Query: 1244 AQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKE 1303 + T EL +Q FESK + ++E + ++ Q+ L ++ + Sbjct: 2090 LWEKC----TGLELEIQTILFESKETH---KINEQLKKENDSLLL--QINVLNKTVKVWQ 2140 Query: 1304 EHLRNLQEKY-ADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQM 1362 E N+ +++ + +L+ + E+ L +E +S + Sbjct: 2141 ETTTNIHQQHDQKQLITFSVLQKVLNQEQ----------QWASQINQIGLSSECESILRQ 2190 Query: 1363 QEQSILNINEENAQLKKSSXXXXXXXXXXXXRVND---AEAKVLELTHQLELKDSEIYQK 1419 Q++ + QL +N+ +++++T Q E Sbjct: 2191 VCQTVYGVPALQKQLDDIKKQSDKEKQEINSLINERCVLSQQIIDITSQHENSSRRNKMS 2250 Query: 1420 THEYTITLTQRNDEFE---NVRQQLVEYEKRIEDLTYEKESELAILRLKMHE-NANHYET 1475 + + Q DE + N++Q +V+ ++ +E L E L++K HE N + Y Sbjct: 2251 EPNSALKINQSMDEEDPSLNIKQLIVKLKRELEILKIENHQ--LTLQMKQHEQNEDIYMK 2308 Query: 1476 MQKESEIERVKLIEELNVKITESVSLNKQVAEL-NKALEEEVAK 1518 K + E L E+LN E + ++V+ N AL E + K Sbjct: 2309 QNKLMKDENRSLSEKLNQMSDELQKMAEKVSNSENGALAEHLKK 2352 Score = 126 bits (304), Expect = 5e-27 Identities = 231/1225 (18%), Positives = 528/1225 (43%), Gaps = 104/1225 (8%) Query: 140 QLGDVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXX 199 Q+ D L + + LS +Q +++ ++ +LQ+ +N+K+Q + A Sbjct: 1130 QIEDQEKLISQQNNQAQQLSEIQEQLQDLQKNNEELQQNLNDKEQNYDILQNA----YYD 1185 Query: 200 XXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKL 259 ED Q+++ +Q + + E D+ + L+ ++ +I+ + + Sbjct: 1186 IGDQKKNLEEEIEDKNQEIS-IQNRDLKIYKEQIDQNKALINQLQE---QIAQFRNSANI 1241 Query: 260 LEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIA 319 A +++ + + +ELE K + + + E+E + Sbjct: 1242 NFAENCKLNEQVQMMKKELESYQIDSKQNLDERSDKIKDLEQQIIDLQNELENQ------ 1295 Query: 320 NMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTA 379 ++ K +E LN +++T++ L++ + S+ + + + + K Sbjct: 1296 -QFQIQYKDSKIEELNNNLQETSENLDDIKQELEITSRQLKNEQAQKEEELKCKQQLEGI 1354 Query: 380 SKMKSPWSQLSSETLNQDTDKKIN-KNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXX 438 + + +Q T NQ + ++ N+I + I+SL K+ + + EK Sbjct: 1355 IQQQKLEAQQYILTTNQQQENLLSLHNKIIEYCNEIESL-KNQISTLQIECEKQQKEMEV 1413 Query: 439 XXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVN-EIAKVQEQLKQ-ELNDEIKDV 496 + + + Q + ++ E + + T ++++ + ++QE+L+ E +EI + Sbjct: 1414 LNENLNQANTLLEDQKSNLENSEF-QINYFQTQSKEIKIQYDQLQEKLQDLEQENEILNR 1472 Query: 497 NVKDLIEKLKSAEEQITQLNDEIDAANKN---MIKVKSNHKLKLKQMQKTIDNFSKVSDS 553 N + +K + + + L EI ++ + + + N++ +++++ TI+ K D+ Sbjct: 1473 NQSNNAQKQEQIQNEKYILQQEISQLKQSLATLFEERQNNQDRIQELIFTIE-LQKSEDA 1531 Query: 554 NKE--IVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAET 611 K+ I +T + L Q++ EL+E+ Q ++ I++ + + + ENL + Sbjct: 1532 KKDQKIELITNQELDLQQRLIELQEQNTTYQQNI------ESIQNQLKDEQLITENLKQQ 1585 Query: 612 RLKAISLLESQK-FDLVQELHILQQKYDEVEDKLADISQ--LQSDQVCSEIKSVHLEEQI 668 K ++ K ++VQ L Q+ +++K+A + Q +Q+ ++ S ++++ E+QI Sbjct: 1586 NEKDQKQIDELKNIEIVQ----LNQQIVNLKEKIAFLEQNEIQTSELSSHLENLRQEKQI 1641 Query: 669 DALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNY--IQENMDLTD-KLE 725 +KE EN KL KE++ + + D + QNY +QE M + K E Sbjct: 1642 ----KEQKEKLFREENDKL-KEEINNFKNQINQLERDNITNEQNYHQLQEEMKTIEIKYE 1696 Query: 726 KMSAEKISELLAKINHEEQSKIQT----QFGIDAKIQERDLYIENIESELSKYKSRICRL 781 ++ ++ + L ++N ++ +I Q + K+++ + I+ + E +++I +L Sbjct: 1697 QLKTQE--QQLIQLNQDKSEQISNLKVIQTDFEQKLEQLNNEIKVYQEEKQTQENKISQL 1754 Query: 782 EESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQE----DELVNRLAVLMDHDRVV 837 E +E++R S+ + +QL +++ +K Q+ D+L N++ +L + Sbjct: 1755 NELQLQLENQRESITLELEQLNEQIKDLKKQSEINACQQNEKIDQLTNQITLLQQKNEEQ 1814 Query: 838 EKQLLEIEHENKELQKKNQILLEENQ-NLQISLSDMQQHYNALVEKANRTDLAESESTKY 896 E Q+ E+ +N+ELQ + +E+ Q Q + + ++Y + N + A+ + Sbjct: 1815 ENQIKELSLQNEELQDQQLQFMEQLQTEKQAHNTQLSENYQLQEKLQNELENAQQSKDQV 1874 Query: 897 QTQLRDLESNLKRITHEHQTLIVQKKKE-----IEDLEIEFNTQIESAIRDKKVLNEKYE 951 Q ++L + + + ++L+ ++++ I++ +I + E ++ +EK Sbjct: 1875 QRLEQELYQLQQALLDKDESLVRWREQQCCSQYIQNEQIGQSQNTEQIDKENNNESEKLN 1934 Query: 952 KNI---EYVTQLEAQLQEYKNNI-ENLNMNVEELNKMNLELIDKHVQKQQTQSP----DY 1003 K I LE Q +YK + E++N + +LE +K +QQ P + Sbjct: 1935 KGIMQESLSNPLEDQDNDYKVEMKEHVNSRI-----FDLEFDEKSGTQQQNILPAVSENV 1989 Query: 1004 TEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEE 1063 +E Y I + L K + + + ++ Q+ ++ + +Q +E ++++ Sbjct: 1990 SEAYDLAIKRSMGLSKDQIIQQLQDQNRLLQQQIENLNQENIIYESPSQHKALIEELQQQ 2049 Query: 1064 MQRVSKQLLDSKQHNEELQILVREQ-DDQIKELKETKLTFEMNIPKTEGMIISSTIEPMS 1122 +Q++ Q L + LQ+L+ E DD+ EL + + + + K G+ + I+ + Sbjct: 2050 IQQLKNQQL-QRIIQSPLQVLIGEHLDDEKDELNQQE-KYHLLWEKCTGLELE--IQTIL 2105 Query: 1123 DDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLN 1182 ++ L +Q + ++V Q N Q ++I L Sbjct: 2106 FESKETHKINEQLKKENDSLLLQIN---VLNKTVKVWQETTTNIHQQHDQKQLITFSVL- 2161 Query: 1183 TELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQH 1242 V+NQEQ Q S++ Q+ LS+ E SI V Q + + L KQ Sbjct: 2162 -----QKVLNQEQ--QWASQINQIG------LSSECE---SILRQVCQTVYGVPALQKQ- 2204 Query: 1243 LAQREADFQKTEHELRVQLSAFESKYEQLLD-SVQSSTQEETNKIVTMEQVTSLQNKLQD 1301 L + K + E+ ++ +Q++D + Q NK+ + N+ D Sbjct: 2205 LDDIKKQSDKEKQEINSLINERCVLSQQIIDITSQHENSSRRNKMSEPNSALKI-NQSMD 2263 Query: 1302 KEEHLRNLQEKYADVINQIEILRSE 1326 +E+ N+++ + ++EIL+ E Sbjct: 2264 EEDPSLNIKQLIVKLKRELEILKIE 2288 Score = 74.9 bits (176), Expect = 2e-11 Identities = 170/848 (20%), Positives = 335/848 (39%), Gaps = 73/848 (8%) Query: 756 KIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSE 815 K + R Y E +S + S + S + Y + ++D S L+++ ++ Sbjct: 56 KNRTRANYSEYFDSRKLPFNSTLQPSRSSSCKKKRHFYDEKVESDGKVSQLEDQNMQIND 115 Query: 816 YTIQEDELVNRLAVLMDHDRVVEKQLLEIEHEN-KELQKKNQILLEENQNLQISLSDMQQ 874 + + N + D +EK LEIE N +L Q EE + + M+Q Sbjct: 116 F------IANIPLCKLSKDEQIEK--LEIEKSNLHKLTSGYQKKAEERKTI------MKQ 161 Query: 875 HYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHE-HQTLIVQKKKEIEDLEIEFN 933 YN L K + Y Q+ + L++ HE HQ L K + +++E N Sbjct: 162 LYNILKTKDQEIEYLRKN---YDNQILIQQQKLEQFKHECHQQL---DKADSRIIKLEGN 215 Query: 934 TQIESAIRDKKV--LNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDK 991 Q + K++ L K EK + +++L + QE K I+ + N+ L + E Sbjct: 216 LQTALQYKQKRLNDLLVKEEKMRDILSKL-IKKQESKEKIDEVK-NI--LAFIAREKSRF 271 Query: 992 HVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESK-- 1049 K+Q + + NE KL +L E ++ +K+N QVS S Y K Sbjct: 272 ETPKKQNSQHEQIDNIQNEHQKLVSL----HENVMLQIEKLNY-QVSQCLQTSQYGQKDT 326 Query: 1050 LAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQ---ILVREQDDQIKELKETKLTFEMNI 1106 + + + L+ M + L D Q +LQ + ++ + K++ K +N Sbjct: 327 IKELSQNLKEMINQFSLSKNTLKDKDQKLIQLQNDLMKYKKLVENKKDIDTQKYIQVINE 386 Query: 1107 PKTEGMIISS-----TIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQS 1161 K E + I+ + NN + +K Q + + + ++ Q + Sbjct: 387 LKLESSNLEKKYQQLVIQEKFGEENNQELQNLNDQLNVQIIKQQSQIQLLHKQIDDQNKV 446 Query: 1162 AKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELR 1221 N ++ + Y Q E E + QE+IN+LK L LN + D+LL + +L+ Sbjct: 447 MMTNEKIIQQYQ---QKEKQLYEELDNQKDQQEEINKLKISLISLNNQKDHLLENIEQLQ 503 Query: 1222 SSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQE 1281 + I S D + + + Q+ K + + L +E+ Y + L QE Sbjct: 504 NEIISKND-----VINQAENQINQQVRQLNKGQQD----LIKYEN-YNEELQQRNKILQE 553 Query: 1282 ETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIED--EKVAFXXXXX 1339 K LQ+KLQD L L+ + + +QI++L+ E + E++ Sbjct: 554 RLKKAEDNNLQQILQDKLQDINNKLELLKNENESLSHQIQVLQDEKDKYFEQLIQLIKQK 613 Query: 1340 XXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAE 1399 QS K + I + N N Q+ K ++ Sbjct: 614 QNNLLYKSQSPKNAISRQSSKFGDQLFISDGN--NKQISKFQ-TELDKFDEIISQITSKL 670 Query: 1400 AKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIE-DLTYEKESE 1458 +V + + + E ++ +Y + ++ + + Q L ++ +++ +++ + Sbjct: 671 IQVEQQKNDFRNLNLEQQKQNSQYLLQISNLEQDNKKYSQMLQQWHQQMTGNISVNLDQN 730 Query: 1459 LAILRLKMHENANHYETMQKESEIERVK-----LIEELNVKITESVSL---NKQVAELNK 1510 I++L E + ++ ++ ++ EELN++I E L NKQ E+ + Sbjct: 731 QDIIKLVKQELKKLKKLEEEYQQLRQINSNLTLAQEELNLEIEEKNQLLEQNKQQLEIEQ 790 Query: 1511 ALEEEVAKTNEMQTALENQEIEIVTLNDEI-TNLQNMVRASSSKIQKHVSFASDTKQGRD 1569 + K N ++ +NQ +++ +N ++ ++ + + + K S + T + +D Sbjct: 791 EQLQNAIKEN-LELKQQNQTQKLLEVNKQLELQIEGLKQKEKEQQAKLESLKTQT-ENQD 848 Query: 1570 EQLDNTMN 1577 ++L N Sbjct: 849 KKLIQNQN 856 Score = 64.9 bits (151), Expect = 2e-08 Identities = 159/845 (18%), Positives = 342/845 (40%), Gaps = 70/845 (8%) Query: 92 ESLANTLKQKEILMEKIKQ-----YKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDV-- 144 ES+ N LK ++++ E +KQ K++ + + IV+ + ++ Sbjct: 1566 ESIQNQLKDEQLITENLKQQNEKDQKQIDELKNIEIVQLNQQIVNLKEKIAFLEQNEIQT 1625 Query: 145 THLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINE-KDQIIEAKNKATTXXXXXXXXX 203 + LS+ ++ + + K K+ L+E+IN K+QI + + T Sbjct: 1626 SELSSHLENLRQEKQIKEQKEKLFREENDKLKEEINNFKNQINQLERDNITNEQNYHQLQ 1685 Query: 204 XXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAA 263 + K + K QE + + K E+ LK I++ D LE+ N ++ Sbjct: 1686 EEMKTI---EIKYEQLKTQEQQLIQLNQDKSEQISNLKVIQT-DFE-QKLEQLNNEIKVY 1740 Query: 264 RFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTE 323 + E + +K++Q L + +Q E + K + E + + + Sbjct: 1741 QEEKQTQENKISQ-LNELQLQLENQRESITLELEQLNEQIKDLKKQSEINACQQNEKIDQ 1799 Query: 324 LTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKK-GSPLISRKSGRNTASKM 382 LT +I LL+ Q N+E EN++ + +++ + + L + K NT Sbjct: 1800 LTNQITLLQ-------QKNEEQENQIKELSLQNEELQDQQLQFMEQLQTEKQAHNT---Q 1849 Query: 383 KSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVI---SEKDTXXXXXX 439 S QL + N+ + + +K+++ +LE + L + L+DK+ + E+ Sbjct: 1850 LSENYQLQEKLQNELENAQQSKDQVQRLEQELYQLQQALLDKDESLVRWREQQCCSQYIQ 1909 Query: 440 XXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVK 499 G+ Q+ E+ E ++ G E ++ + Q+ + E+K+ +V Sbjct: 1910 NEQIGQSQNTEQIDKENNNESE---KLNKGIMQESLSNPLEDQD---NDYKVEMKE-HVN 1962 Query: 500 DLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVR 559 I L+ E+ TQ + + A ++N V + L +K+ SK ++ I + Sbjct: 1963 SRIFDLEFDEKSGTQQQNILPAVSEN---VSEAYDLAIKRSM----GLSK----DQIIQQ 2011 Query: 560 LTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLL 619 L ++ L Q++ L +E N+ + E + ++ + L + +L Sbjct: 2012 LQDQNRLLQQQIENLNQE--NIIYESPSQHKALIEELQQQIQQLKNQQLQRIIQSPLQVL 2069 Query: 620 ESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVH-LEEQIDALSAS-KKE 677 + D ++ Q+KY + +K + +L+ + E K H + EQ+ + S + Sbjct: 2070 IGEHLDDEKDELNQQEKYHLLWEKCTGL-ELEIQTILFESKETHKINEQLKKENDSLLLQ 2128 Query: 678 LALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLA 737 + ++ + +K+ +E + + + + LQ + + ++ ++ E + Sbjct: 2129 INVLNKTVKVWQETTTNIHQQHDQKQLITFSVLQKVLNQEQQWASQINQIGLSSECESIL 2188 Query: 738 KINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRI---CRLEESI--AVMEDRR 792 + QT +G+ A ++ D + + E + S I C L + I + Sbjct: 2189 R------QVCQTVYGVPALQKQLDDIKKQSDKEKQEINSLINERCVLSQQIIDITSQHEN 2242 Query: 793 YSLERKADQLGSYLQEKQKAYSE-YTIQEDELVNRLAVLMDHDRVVEKQL-LEI-EHENK 849 S K + S L+ Q E ++ +L+ +L ++ ++ QL L++ +HE Sbjct: 2243 SSRRNKMSEPNSALKINQSMDEEDPSLNIKQLIVKLKRELEILKIENHQLTLQMKQHEQN 2302 Query: 850 E--LQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTD---LAESESTKYQTQLRDLE 904 E K+N+++ +EN++L L+ M + EK + ++ LAE Q L+ Sbjct: 2303 EDIYMKQNKLMKDENRSLSEKLNQMSDELQKMAEKVSNSENGALAEHLKKNIQKFFEALQ 2362 Query: 905 SNLKR 909 K+ Sbjct: 2363 QEKKQ 2367 >UniRef50_A2FK27 Cluster: Viral A-type inclusion protein, putative; n=1; Trichomonas vaginalis G3|Rep: Viral A-type inclusion protein, putative - Trichomonas vaginalis G3 Length = 1677 Score = 169 bits (412), Expect = 4e-40 Identities = 254/1193 (21%), Positives = 532/1193 (44%), Gaps = 139/1193 (11%) Query: 470 TNTEDV-NEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLND----------E 518 TNT+ + NE+ KV + KQ L+D++ + E+L E QI Q+N Sbjct: 43 TNTQILTNELNKVNTE-KQSLHDQLTECK-----ERLALKENQIVQINQLYAQAETDLKN 96 Query: 519 IDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNK-----EIVRLTEELHHLSQKVAE 573 + +N +++ + ++K+K+ + K ++ N ++ L E H S+K+ + Sbjct: 97 LQHSNAELVQAFNEERMKMKKENAELTTQLKKAEKNNMDLSNDLSTLIENTHDESEKIED 156 Query: 574 LEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHIL 633 L+E+ L+ + K++ E E + + LLE++ +L Q+L Sbjct: 157 LQEKVKELE--------------TLKKQLEESEKVILEEGEKNQLLENETNNLKQQLSNS 202 Query: 634 QQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDAL-SASKKELALVIENLKLDKEQL 692 + D +++ + ++ + ++++ S K+ L++QI S S I L + L Sbjct: 203 KNNSD-LQNAMDELISM-NEELTS--KNEQLQKQIQEFNSKSSTNDEAAITTLSNENISL 258 Query: 693 YGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFG 752 I + + E+++ K+++ IQ +D K + E + L + + E+ S I+ Sbjct: 259 SNQITERDATIEELLQKIES-IQSELDSKQKELQQLQENNANLQSSNDSEKDSMIEDLIR 317 Query: 753 IDAKIQ-ERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQK 811 ++Q E L E + + Y+S++ LE ++ ++ S ++ L S LQ K+ Sbjct: 318 KTDELQKEIGLKSEELSTTKKDYESKLQNLESKLSELQISMDSKTKEVSDLQSQLQLKEN 377 Query: 812 AYSE---YTIQEDELVNRL--AVLMDHDRVVEK--QLLEIEHENKELQK-----KNQI-- 857 A SE T Q + RL VL +++ + +K ++ + + E ++LQK K++I Sbjct: 378 AISESSNATTQISSELERLNGIVLRNNELIQQKDTEITKTKQELEDLQKLNDKLKSKINE 437 Query: 858 LLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTL 917 L E N L LS++QQ EK ++++ +S QT + E +I + Q Sbjct: 438 LTETNNKLVSDLSELQQMSKETEEKL-KSEIESIQSQLNQTNVMLKEKEGSQIQFDSQIS 496 Query: 918 IVQKK-KEIE---DLEIEFNTQIESAIRDKKVLNEKYEK-NIEYVTQ-LEAQL------- 964 +QK+ +IE ++E NT + + + + E YEK N E Q LEA L Sbjct: 497 EIQKRYNDIEVQLKEKLEANTSLMNQVEELSNKVEYYEKQNFEKRNQELEANLSAITSEY 556 Query: 965 QEYKNNIENLNMNVEE-LNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDE 1023 Q YK+ E +++++ L+K N L + +QK S D +Y NE+N+ AL+ E Sbjct: 557 QSYKSQSEQKILDIQQKLDKTNNNL--EKLQKDHETSKD---EYHNELNEKEALISSLKE 611 Query: 1024 EIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHN-EELQ 1082 E ++NQ++ Q+S ++ + ++Q ++L EE+ +++ +QL + K +ELQ Sbjct: 612 ENSSINQRLQ--QIS-----NENKELMSQINSQLSG-EEKSKQIIEQLTNEKNKQIQELQ 663 Query: 1083 ILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXL 1142 V + Q K+ T + K E + +S+ + + Sbjct: 664 NKVNSLNQQRNNDKQALKTRAVEFFKNEKQQFDQILNIISEKEQKL--GQMSEQMAKKLI 721 Query: 1143 KVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETL--NTELTGHDVVNQEQ--INQ 1198 V+ +E+ E L+++ + ++L K+ +L + N + T ++ +++ I++ Sbjct: 722 LVRRLQEYSIETEKLKDE---VTSQLDIVQQKVKELNQIVENDDATNKQILEEKEQIISE 778 Query: 1199 LKSKLEQLNTEND--------------NLLSTVAELRSSISSAVDQRGFEIAELWKQHLA 1244 L+ K+E+L + N+ NL + + E+++ IS + EI +L ++ Sbjct: 779 LEQKIEELESANEELGNSINEKEEDINNLNTKLNEIQNQISQKDSEENNEITKLKDENRT 838 Query: 1245 QREA--DFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTM-----EQVTSLQN 1297 Q E + +K + L++ +S + + E+ LDS+ + + ++ + E++ +L Sbjct: 839 QLEKINNLEKEKENLQISVSQVKKQLEEQLDSMSAQSNQQVQTYIDQIKSQNEKINNLDR 898 Query: 1298 KLQD---KEEHLRNL----QEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXX 1350 ++ + K E L+N Q+ Y + ++ ++I S++ EK F Sbjct: 899 EISEYKQKNEELQNSLDGNQKSYEEELSSLKIQLSKLNSEKETFSNEINELKHDIANKDD 958 Query: 1351 DLRTENQSYKQMQEQSIL---NINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTH 1407 + + + ++++ ++++ N+ E +L +SS N+ V+E + Sbjct: 959 QISLKEKEIQKIENENLVLSQNLTEMKEKLNQSSEELTKLR-------NEYNNSVIEYQN 1011 Query: 1408 QLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMH 1467 Q+ SE K E + Q E E + ++ E+ L+ E +L +M Sbjct: 1012 QISALKSEKEGKQMENNENVKQLQSEKEELIKKFTNLEEEKNKLSKSMEKKLQDYAEQMA 1071 Query: 1468 ENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALE 1527 + + ++++ + ++ + + ++ + +N +E K EEE+ K + A Sbjct: 1072 ASQDTISLLEQQK--QNLEKVSQEKIQEMKQKCINLVESE-RKKHEEEIEKLKNLVQAKS 1128 Query: 1528 NQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKEL 1580 +++ + N I NLQ+ + S+ I+ ++S K L +N E+ Sbjct: 1129 DEQTKKSLEN--IQNLQSKLEESNKTIE-NLSSQIKEKDENSLNLQQKLNSEI 1178 Score = 168 bits (409), Expect = 1e-39 Identities = 283/1417 (19%), Positives = 616/1417 (43%), Gaps = 131/1417 (9%) Query: 235 EKQRLLKDI-ESKD---VRISSLEEANKLLEAARFEI-SLEHSKLAQELEQXXXXXXXXX 289 EKQ L + E K+ ++ + + + N+L A ++ +L+HS EL Q Sbjct: 58 EKQSLHDQLTECKERLALKENQIVQINQLYAQAETDLKNLQHSNA--ELVQAFNEERMKM 115 Query: 290 XXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKL 349 ++ + + ++ S I N + ++KIE L+ ++ K+LE Sbjct: 116 KKENAELTTQLKKAEKNNMDLSNDLSTLIENTHDESEKIEDLQEKVKELETLKKQLEESE 175 Query: 350 ATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAK 409 + E + + + L + S S +++ +L S +N++ +KNE + Sbjct: 176 KVILEEGEKNQLLENETNNLKQQLSNSKNNSDLQNAMDELIS--MNEELT---SKNE--Q 228 Query: 410 LEMVIQSLN-KDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHV 468 L+ IQ N K + E I+ +D I +L L+ + ++ + Sbjct: 229 LQKQIQEFNSKSSTNDEAAITTLSNENISLSNQITERDATIEEL-LQKIESIQS----EL 283 Query: 469 GTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIK 528 + +++ ++ + L Q ND KD ++DLI K +++I ++E+ K+ Sbjct: 284 DSKQKELQQLQENNANL-QSSNDSEKDSMIEDLIRKTDELQKEIGLKSEELSTTKKDYES 342 Query: 529 VKSNHKLKLKQMQKTIDNFSK-VSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQ-LHLV 586 N + KL ++Q ++D+ +K VSD ++ + S ++ E L + L Sbjct: 343 KLQNLESKLSELQISMDSKTKEVSDLQSQLQLKENAISESSNATTQISSELERLNGIVLR 402 Query: 587 DYDSGRMIESDVYKKMIEMENLAET--RLKA-ISLLESQKFDLVQELHILQQKYDEVEDK 643 + + + ++++ K E+E+L + +LK+ I+ L LV +L LQQ E E+K Sbjct: 403 NNELIQQKDTEITKTKQELEDLQKLNDKLKSKINELTETNNKLVSDLSELQQMSKETEEK 462 Query: 644 L-ADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLEND 702 L ++I +QS + + E + E+ ++++ ++ L N Sbjct: 463 LKSEIESIQSQLNQTNVMLKEKEGSQIQFDSQISEIQKRYNDIEVQLKEKLEANTSLMNQ 522 Query: 703 KEDIMNKLQNYIQENMDLTDK-LEKMSAEKISELLAKINHEEQSKIQTQFGIDA------ 755 E++ NK++ Y ++N + ++ LE + SE + + EQ + Q +D Sbjct: 523 VEELSNKVEYYEKQNFEKRNQELEANLSAITSEYQSYKSQSEQKILDIQQKLDKTNNNLE 582 Query: 756 KIQ-ERDLYIENIESELSKYKSRICRLEESIAVMEDR--RYSLERKA--DQLGSYL--QE 808 K+Q + + + +EL++ ++ I L+E + + R + S E K Q+ S L +E Sbjct: 583 KLQKDHETSKDEYHNELNEKEALISSLKEENSSINQRLQQISNENKELMSQINSQLSGEE 642 Query: 809 KQKAYSEYTIQE-----DELVNRLAVLMDHDRVVEKQLLE---IEHENKELQKKNQIL-- 858 K K E E EL N++ L + R +KQ L+ +E E Q+ +QIL Sbjct: 643 KSKQIIEQLTNEKNKQIQELQNKVNSL-NQQRNNDKQALKTRAVEFFKNEKQQFDQILNI 701 Query: 859 -LEENQNL---------QISLSDMQQHYNALVEK-----ANRTDLAESESTKYQTQLRDL 903 E+ Q L ++ L Q Y+ EK ++ D+ + + + + + Sbjct: 702 ISEKEQKLGQMSEQMAKKLILVRRLQEYSIETEKLKDEVTSQLDIVQQKVKELNQIVEND 761 Query: 904 ESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKK------------VLNEKYE 951 ++ K+I E + +I + +++IE+LE N ++ ++I +K+ + N+ + Sbjct: 762 DATNKQILEEKEQIISELEQKIEELE-SANEELGNSINEKEEDINNLNTKLNEIQNQISQ 820 Query: 952 KNIEY---VTQLEAQLQ---EYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTE 1005 K+ E +T+L+ + + E NN+E N++ + +++ + QS + Sbjct: 821 KDSEENNEITKLKDENRTQLEKINNLEKEKENLQISVSQVKKQLEEQLDSMSAQSNQQVQ 880 Query: 1006 QYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQ 1065 YI++I N + D EI QK Q S YE +L+ +L + E + Sbjct: 881 TYIDQIKSQNEKINNLDREISEYKQKNEELQNSLDGNQKSYEEELSSLKIQLSKLNSEKE 940 Query: 1066 RVSKQLLDSKQH--NEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSD 1123 S ++ + K N++ QI ++E+ +I++++ L N+ + + + S+ E ++ Sbjct: 941 TFSNEINELKHDIANKDDQISLKEK--EIQKIENENLVLSQNLTEMKEKLNQSS-EELTK 997 Query: 1124 DANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNT 1183 N + LK ++E + ++ E +L +E +E K LE Sbjct: 998 LRNEYNNSVIEYQNQISALKSEKEGKQMEN----NENVKQLQSEKEELIKKFTNLEEEKN 1053 Query: 1184 ELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHL 1243 +L ++ +L+ EQ+ D +S + + + ++ ++ I E+ ++ + Sbjct: 1054 KL------SKSMEKKLQDYAEQMAASQDT-ISLLEQQKQNLEKVSQEK---IQEMKQKCI 1103 Query: 1244 AQREADFQKTEHELRVQLSAFESKY-EQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDK 1302 E++ +K E E+ + ++K EQ S+++ ++ + + + +L +++++K Sbjct: 1104 NLVESERKKHEEEIEKLKNLVQAKSDEQTKKSLENIQNLQSKLEESNKTIENLSSQIKEK 1163 Query: 1303 EEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQM 1362 +E+ NLQ+K I + SE+ +EK N+ ++ Sbjct: 1164 DENSLNLQQKLNSEIQNLNSRISELNEEKTTLSQSLSTCQSENSKL-------NEEILKL 1216 Query: 1363 QEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIY-QKTH 1421 ++ ++ N+ + K++ + + +++L +L+ K +EI QK Sbjct: 1217 KQNNLNYDKTLNSIVSKNNKLLETISLSFENSLVKLNSNIMKLISKLKTKVNEIADQKRA 1276 Query: 1422 EYTI---TLTQRNDEFENV---RQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYET 1475 I +++ R +EF+ + ++++ ++ + E E L L +K+ + YE+ Sbjct: 1277 VMEIMANSVSAREEEFDKIADKKEEIRNESIKLNQMKEENEKTLQELNIKLRD----YES 1332 Query: 1476 MQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTN--EMQTALENQEIEI 1533 ++++ E L+ LN K +E K+++E K +E++ + + E + + + IE+ Sbjct: 1333 IKRDYE----SLMSSLNAKKSEIEQKEKELSEKEKINDEKLTELSVAEKKALMLQRTIEM 1388 Query: 1534 VTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDE 1570 ++ +N+ RA + ++ FA + Q R E Sbjct: 1389 DRTQYDMEG-ENIRRAKNELEKRRHQFALEVAQHRIE 1424 Score = 168 bits (409), Expect = 1e-39 Identities = 301/1489 (20%), Positives = 624/1489 (41%), Gaps = 126/1489 (8%) Query: 147 LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXX 206 LSN I E+D + L K++ +++ +L K E Q+ E + Sbjct: 258 LSNQITERDATIEELLQKIESIQS---ELDSKQKELQQLQENNANLQSSNDSEKDSMIED 314 Query: 207 XXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRL---LKDIE----SKDVRISSLEEANKL 259 ++ ++++ E + +++ + Q L L +++ SK +S L+ +L Sbjct: 315 LIRKTDELQKEIGLKSEELSTTKKDYESKLQNLESKLSELQISMDSKTKEVSDLQSQLQL 374 Query: 260 LEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQ--SIEPSCEEKTEIEEKGSLE 317 E A E S ++++ ELE+ + + E+ ++ +K + Sbjct: 375 KENAISESSNATTQISSELERLNGIVLRNNELIQQKDTEITKTKQELEDLQKLNDKLKSK 434 Query: 318 IANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRN 377 I +TE K L+ L+ +++Q +KE E KL + E +++ S + + ++ K G Sbjct: 435 INELTETNNK--LVSDLS-ELQQMSKETEEKLKS---EIESIQSQLNQTNVMLKEKEG-- 486 Query: 378 TASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDK-EYVISEKDTXXX 436 S+++ SQ+S E + D ++ E + + + ++L +K EY EK Sbjct: 487 --SQIQFD-SQIS-EIQKRYNDIEVQLKEKLEANTSLMNQVEELSNKVEYY--EKQNFEK 540 Query: 437 XXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNE-IAKVQEQLKQELNDEIKD 495 + ++ Q Q + ++ + + N + K+Q+ + ++ + Sbjct: 541 RNQELEANLSAITSEYQSYKSQSEQ--KILDIQQKLDKTNNNLEKLQKDHETSKDEYHNE 598 Query: 496 VNVKD-LIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSN 554 +N K+ LI LK I Q +I NK ++ + N +L ++ K I ++ N Sbjct: 599 LNEKEALISSLKEENSSINQRLQQISNENKELMS-QINSQLSGEEKSKQIIE-QLTNEKN 656 Query: 555 KEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLK 614 K+I L +++ L+Q + +K L+ V++ E + +++ + + E +L Sbjct: 657 KQIQELQNKVNSLNQ---QRNNDKQALKTRAVEFFKN---EKQQFDQILNIISEKEQKLG 710 Query: 615 AISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVH-LEEQIDALSA 673 +S ++K LV+ L Q+Y +KL D Q D V ++K ++ + E DA + Sbjct: 711 QMSEQMAKKLILVRRL----QEYSIETEKLKDEVTSQLDIVQQKVKELNQIVENDDATNK 766 Query: 674 SK--------KELALVIENLKLDKEQLYGTIKDLENDKEDI---MNKLQNYI-QENMDLT 721 EL IE L+ E+L +I + E D ++ +N++QN I Q++ + Sbjct: 767 QILEEKEQIISELEQKIEELESANEELGNSINEKEEDINNLNTKLNEIQNQISQKDSEEN 826 Query: 722 DKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSK----YKSR 777 +++ K+ E ++L KIN+ E+ K Q + ++ + ++++ ++ ++ Y + Sbjct: 827 NEITKLKDENRTQL-EKINNLEKEKENLQISVSQVKKQLEEQLDSMSAQSNQQVQTYIDQ 885 Query: 778 ICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVV 837 I E I ++ ++K ++L + L QK+Y E + L +L+ L Sbjct: 886 IKSQNEKINNLDREISEYKQKNEELQNSLDGNQKSYEE---ELSSLKIQLSKLNSEKETF 942 Query: 838 EKQLLEIEHE--NKELQ---KKNQILLEENQNLQIS--LSDMQQHYNALVEKANRTDLAE 890 ++ E++H+ NK+ Q K+ +I EN+NL +S L++M++ N E+ + Sbjct: 943 SNEINELKHDIANKDDQISLKEKEIQKIENENLVLSQNLTEMKEKLNQSSEELTKLRNEY 1002 Query: 891 SEST-KYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEK 949 + S +YQ Q+ L+S + E+ + Q + E E+L +F T +E +K L++ Sbjct: 1003 NNSVIEYQNQISALKSEKEGKQMENNENVKQLQSEKEELIKKF-TNLEE---EKNKLSKS 1058 Query: 950 YEKNIE-YVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYI 1008 EK ++ Y Q+ A ++ I L + L K++ E I + QK +++ Sbjct: 1059 MEKKLQDYAEQMAAS----QDTISLLEQQKQNLEKVSQEKIQEMKQKCINLVESERKKHE 1114 Query: 1009 NEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVS 1068 EI KL L++ K +E + + N Q + +SKL + +EN+ +++ Sbjct: 1115 EEIEKLKNLVQAKSDE--QTKKSLENIQ--------NLQSKLEESNKTIENLSSQIKEKD 1164 Query: 1069 KQLLDSKQH-NEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANN 1127 + L+ +Q N E+Q L + +I EL E K T ++ + E + NN Sbjct: 1165 ENSLNLQQKLNSEIQNL----NSRISELNEEKTTLSQSLSTCQSENSKLNEEILKLKQNN 1220 Query: 1128 VDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQS--AKLNTELQECYTKIIQLETLNTEL 1185 ++ K+ E E S+++ S KL ++L+ +I + E+ Sbjct: 1221 LNYDKTLNSIVSKNNKLLETISLSFENSLVKLNSNIMKLISKLKTKVNEIADQKRAVMEI 1280 Query: 1186 TGHDV-VNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSA-VDQRGFEIAELWKQHL 1243 + V +E+ +++ K E++ E+ L E ++ + R +E + Sbjct: 1281 MANSVSAREEEFDKIADKKEEIRNESIKLNQMKEENEKTLQELNIKLRDYESIK------ 1334 Query: 1244 AQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKE 1303 D++ L + S E K ++L + + + ++ T V ++ LQ ++ Sbjct: 1335 ----RDYESLMSSLNAKKSEIEQKEKELSEKEKINDEKLTELSVAEKKALMLQRTIEMDR 1390 Query: 1304 EHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQ-SYKQM 1362 E N++E R + E D+ N+ + K++ Sbjct: 1391 TQYDMEGENIRRAKNELEKRRHQFALE----VAQHRIEYEEFNEKKKDIEQMNEKATKKL 1446 Query: 1363 QEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHE 1422 Q+ +L +EN K + E L+ ++ I + + Sbjct: 1447 QKAELLK--QENENKLKEIAQNVSEAKQTMLDAEKIKQNADEREKFLKQEEERISNLSKD 1504 Query: 1423 YTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEI 1482 + ND +L EK+ +++ + ILR+K + KE EI Sbjct: 1505 AEFNTQKANDIMHKAEDKLAMNEKKEKEIEQKMSEVEKILRMKKDLEEKSLQMSNKEKEI 1564 Query: 1483 ERV--KLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEI 1540 ++ ++ +LNV + ++ ++ + L K +E+ K +E+ L +I I + + Sbjct: 1565 VQMMDQVKSKLNV-VEQAQNVKNENENLKKQNDEKDKKISELNHKL---KIAISKIKSD- 1619 Query: 1541 TNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAEL 1589 QN S + + F + Q R++ L ++ LLD + L Sbjct: 1620 QKKQNENGISEVLRRSFLMFVAQDWQHREQMLPGILS--LLDCTDQERL 1666 Score = 132 bits (319), Expect = 8e-29 Identities = 191/846 (22%), Positives = 389/846 (45%), Gaps = 102/846 (12%) Query: 808 EKQKAYSEYTIQEDE-LVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQ 866 +K KA + +I + L N L + + + QL E + E L K+NQI+ + NQ Sbjct: 32 DKHKAQLKQSITNTQILTNELNKVNTEKQSLHDQLTECK-ERLAL-KENQIV-QINQLYA 88 Query: 867 ISLSDMQ--QHYNA-LVEKANRTDLA-ESESTKYQTQLRDLESNLKRITHEHQTLIVQ-- 920 + +D++ QH NA LV+ N + + E+ + TQL+ E N ++++ TLI Sbjct: 89 QAETDLKNLQHSNAELVQAFNEERMKMKKENAELTTQLKKAEKNNMDLSNDLSTLIENTH 148 Query: 921 -KKKEIEDLEI---EFNTQIESAIRDKKVLNEKYEKN--IEYVTQ-LEAQLQEYKNNIEN 973 + ++IEDL+ E T + +KV+ E+ EKN +E T L+ QL KNN + Sbjct: 149 DESEKIEDLQEKVKELETLKKQLEESEKVILEEGEKNQLLENETNNLKQQLSNSKNN-SD 207 Query: 974 LNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKIN 1033 L ++EL MN EL K+ Q Q+ +I + N+ DE I ++ Sbjct: 208 LQNAMDELISMNEELTSKNEQLQK------------QIQEFNSKSSTNDEAAITT---LS 252 Query: 1034 NAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILV-REQDDQI 1092 N +S + +++ ++ + + K+E+++ E+ K+L +++N LQ E+D I Sbjct: 253 NENISLSNQITERDATIEELLQKIESIQSELDSKQKELQQLQENNANLQSSNDSEKDSMI 312 Query: 1093 KEL--KETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEF 1150 ++L K +L E+ + E +S+T + N++ K +E + Sbjct: 313 EDLIRKTDELQKEIGLKSEE---LSTTKKDYESKLQNLESKLSELQISMDS-KTKEVSDL 368 Query: 1151 -----IQERSVLQEQSA--KLNTELQECYTKIIQ----LETLNTELTG--HDVVNQEQIN 1197 ++E ++ + +A ++++EL+ +++ ++ +TE+T ++ + +++N Sbjct: 369 QSQLQLKENAISESSNATTQISSELERLNGIVLRNNELIQQKDTEITKTKQELEDLQKLN 428 Query: 1198 -QLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEH- 1255 +LKSK+ +L N+ L+S ++EL+ ++ EI + Q L Q ++ E Sbjct: 429 DKLKSKINELTETNNKLVSDLSELQQMSKETEEKLKSEIESIQSQ-LNQTNVMLKEKEGS 487 Query: 1256 --ELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKL-----QDKEEHLRN 1308 + Q+S + +Y + VQ + E N + M QV L NK+ Q+ E+ + Sbjct: 488 QIQFDSQISEIQKRYNDI--EVQLKEKLEANTSL-MNQVEELSNKVEYYEKQNFEKRNQE 544 Query: 1309 LQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSY-KQMQEQSI 1367 L+ + + ++ + +S+ E + + D T Y ++ E+ Sbjct: 545 LEANLSAITSEYQSYKSQSEQKILDIQQKLDKTNNNLEKLQKDHETSKDEYHNELNEKEA 604 Query: 1368 L--NINEENAQLKKSSXXXXXXXXXXXXRVND---AEAKVLELTHQL-ELKDSEIYQKTH 1421 L ++ EEN+ + + ++N E K ++ QL K+ +I + + Sbjct: 605 LISSLKEENSSINQRLQQISNENKELMSQINSQLSGEEKSKQIIEQLTNEKNKQIQELQN 664 Query: 1422 EYTITLTQRNDEFENVRQQLVEYEK-------RIEDLTYEKESELA----------ILRL 1464 + QRN++ + ++ + VE+ K +I ++ EKE +L IL Sbjct: 665 KVNSLNQQRNNDKQALKTRAVEFFKNEKQQFDQILNIISEKEQKLGQMSEQMAKKLILVR 724 Query: 1465 KMHENANHYETMQKE--SEIERVKL-IEELNVKITESVSLNKQV--------AELNKALE 1513 ++ E + E ++ E S+++ V+ ++ELN + + NKQ+ +EL + +E Sbjct: 725 RLQEYSIETEKLKDEVTSQLDIVQQKVKELNQIVENDDATNKQILEEKEQIISELEQKIE 784 Query: 1514 EEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLD 1573 E + E+ ++ +E +I LN ++ +QN + S+ ++ D + + E+++ Sbjct: 785 ELESANEELGNSINEKEEDINNLNTKLNEIQNQISQKDSEENNEITKLKDENRTQLEKIN 844 Query: 1574 NTMNKE 1579 N + KE Sbjct: 845 N-LEKE 849 Score = 118 bits (284), Expect = 1e-24 Identities = 183/913 (20%), Positives = 377/913 (41%), Gaps = 80/913 (8%) Query: 686 KLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEK------ISELLAKI 739 K D + + ++ L+ + +L+ I LT++L K++ EK ++E ++ Sbjct: 14 KADIDTMRKMLRVLKEKNDKHKAQLKQSITNTQILTNELNKVNTEKQSLHDQLTECKERL 73 Query: 740 NHEEQSKIQ-TQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERK 798 +E +Q Q A+ ++L N E + + R+ +E+ + + K Sbjct: 74 ALKENQIVQINQLYAQAETDLKNLQHSNAELVQAFNEERMKMKKENAELTTQLK-----K 128 Query: 799 ADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQIL 858 A++ L E T E E + L + ++KQL E E E +KNQ+L Sbjct: 129 AEKNNMDLSNDLSTLIENTHDESEKIEDLQEKVKELETLKKQLEESEKVILEEGEKNQLL 188 Query: 859 LEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLI 918 E NL+ LS+ + N +DL Q + +L S + +T +++ Sbjct: 189 ENETNNLKQQLSNSK----------NNSDL--------QNAMDELISMNEELTSKNE--- 227 Query: 919 VQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNV 978 Q +K+I++ + +T E+AI + NE + +T+ +A ++E IE++ + Sbjct: 228 -QLQKQIQEFNSKSSTNDEAAI--TTLSNENISLS-NQITERDATIEELLQKIESIQSEL 283 Query: 979 EELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVS 1038 + K +L + + Q + + + I K + L K EI +++++ + Sbjct: 284 DSKQKELQQLQENNANLQSSNDSEKDSMIEDLIRKTDELQK----EIGLKSEELSTTKKD 339 Query: 1039 YMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKET 1098 Y S + + ESKL++ +++ +E+ + QL + E + +++ L Sbjct: 340 YESKLQNLESKLSELQISMDSKTKEVSDLQSQLQLKENAISESSNATTQISSELERLNGI 399 Query: 1099 KLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQ 1158 L I + + I + E N K+ + +Q+ S + Sbjct: 400 VLRNNELIQQKDTEITKTKQELEDLQKLNDKLKSKINELTETNNKLVSDLSELQQMS--K 457 Query: 1159 EQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVA 1218 E KL +E++ +++ Q + E G + QI++++ + + + L Sbjct: 458 ETEEKLKSEIESIQSQLNQTNVMLKEKEGSQIQFDSQISEIQKRYNDIEVQ----LKEKL 513 Query: 1219 ELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSS 1278 E +S+ + V++ ++ KQ +F+K EL LSA S+Y QS Sbjct: 514 EANTSLMNQVEELSNKVEYYEKQ-------NFEKRNQELEANLSAITSEY-------QSY 559 Query: 1279 TQEETNKIVTMEQ-VTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXX 1337 + KI+ ++Q + N L+ ++ +++Y + +N+ E L S +++E + Sbjct: 560 KSQSEQKILDIQQKLDKTNNNLEKLQKDHETSKDEYHNELNEKEALISSLKEENSSINQR 619 Query: 1338 XXXXXXXXXXXXXDLRTENQSYKQMQEQSILNI-NEENAQLKKSSXXXXXXXXXXXXRVN 1396 + ++ S ++ +Q I + NE+N Q+++ Sbjct: 620 LQQISNENKELMSQINSQ-LSGEEKSKQIIEQLTNEKNKQIQELQNKVNSLNQQRNNDKQ 678 Query: 1397 DAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFEN---VRQQLVEYEKRIEDLTY 1453 + + +E + + +I E L Q +++ + ++L EY E L Sbjct: 679 ALKTRAVEFFKNEKQQFDQILNIISEKEQKLGQMSEQMAKKLILVRRLQEYSIETEKLKD 738 Query: 1454 EKESELAILRLK---MHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNK 1510 E S+L I++ K +++ + + K+ E+ ++I EL KI E S N+++ Sbjct: 739 EVTSQLDIVQQKVKELNQIVENDDATNKQILEEKEQIISELEQKIEELESANEELGNSIN 798 Query: 1511 ALEEEV----AKTNEMQTALENQEI----EIVTLNDE-ITNLQNMVRASSSKIQKHVSFA 1561 EE++ K NE+Q + ++ EI L DE T L+ + K +S Sbjct: 799 EKEEDINNLNTKLNEIQNQISQKDSEENNEITKLKDENRTQLEKINNLEKEKENLQIS-V 857 Query: 1562 SDTKQGRDEQLDN 1574 S K+ +EQLD+ Sbjct: 858 SQVKKQLEEQLDS 870 >UniRef50_A2F3I9 Cluster: Viral A-type inclusion protein, putative; n=1; Trichomonas vaginalis G3|Rep: Viral A-type inclusion protein, putative - Trichomonas vaginalis G3 Length = 1798 Score = 169 bits (412), Expect = 4e-40 Identities = 283/1372 (20%), Positives = 583/1372 (42%), Gaps = 134/1372 (9%) Query: 217 QMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQ 276 Q+T++ E E+ + LL + + +S LE N +++ E+S+L + Sbjct: 252 QLTELNTKLQKAEQEYNSKLNNLLIENNTNKSNLSQLELKNT-------QLNNENSQLKK 304 Query: 277 ELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNC 336 +L + L Q ++ E T E+ + +++L + E L ++ Sbjct: 305 DLSEFSKTLTSKELEASNLRDQ-LKKVSESNTNREDSKQI----ISQLQDQAEQLRNIIK 359 Query: 337 QIRQTNKELENKLATMGTE-SKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLN 395 NK+LE K + S+A+S +K I++ N K+++ QL + L+ Sbjct: 360 AKEDENKKLETKNQRAALKYSEAISKLTKSSDDQITKIDQENM--KLQAQL-QLYQQELS 416 Query: 396 QDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLE 455 + +K+EI+ L+ ++ K + + +++ T KD I L Sbjct: 417 K---VNASKSEISDLKEKLKEREKTIKELSSKLNDITTQSEANMEFERQKDRQIQNL--- 470 Query: 456 HQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQL 515 H E L+ + +E+ K++ + ++L +K K+ +E K ++E I +L Sbjct: 471 ---HSEVAKLLV----EQQKSEVIKIEAEKNRKLVKALK----KEKVELDKKSQEVIAKL 519 Query: 516 NDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELE 575 +I+ N ++ S K+K++Q + + S +S+ L+E++ LS + EL+ Sbjct: 520 QQKINILTNNY-ELISLEKIKMEQTMSS-NLLSVRKESSDTNTYLSEKVTQLSNSLQELK 577 Query: 576 EEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQ-ELHILQ 634 ++ +L+ L + +++ +E+E L L S + +L + ++ Sbjct: 578 KQNKSLKRKLNGLQNDY---NELKSNQVEIEELENENKDRKKKLRSYQNNLTPVKSPKIE 634 Query: 635 QKYDEVEDKLADISQ---LQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQ 691 + E++ KL + L DQ+ +E + ++ I L+ + E++ ++E Sbjct: 635 DENKELKKKLRGLQNDYNLLKDQI-TENDEENKQKMIRRLTKKLGQSEKQFEDVSKEREV 693 Query: 692 LYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQF 751 L I+DL + E KL+N E ++ K A+ IS+L Q +IQ+ Sbjct: 694 LLARIEDLSEENE----KLRNRSNEG---DAEIVKTQADLISKL--------QQQIQSLS 738 Query: 752 GIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQK 811 +D YI ++ E+ + K R+ + +DR ++ K + + E Sbjct: 739 NNPLDFSAKDQYINSLHQEIDELKQRLNENAAKVVTPQDRN-AVPEKEKTIIDMINEDSD 797 Query: 812 AYSEYTIQEDELVNRLA--VLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISL 869 YSE ED ++ R++ E EN E+ +++LEE N + Sbjct: 798 GYSEEEEAEDSGSEAATKDLVPSRQRMIRLSYDEPNTENAEITSL-KVMLEEKTN---EV 853 Query: 870 SDMQQHYNA-----LVEKANR--TDLAESESTK------YQTQLRDLESNLKRITHEHQT 916 +D+++ N L EK N TDL + S K ++ +L++++ + + + Sbjct: 854 NDLKKQINEANDKNLEEKLNEKVTDLKSTLSLKDDIIQRQNDEINELKTHIDSLKSKIEN 913 Query: 917 LIVQK---KKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIEN 973 LI +KE E+ E +++ + E DK +++ +EK I E L+E K +N Sbjct: 914 LIATNNINQKETENKEYDYS-ETEQNNEDKNDIDKMFEKKISNAENQE--LEELKAENDN 970 Query: 974 LNMNV----EELNKMNLELIDKHVQKQQTQSPDYTEQYIN---EINKLNALLKQKDEEII 1026 L + + ++ E I K+ ++++ + ++ N E+ KLN +L +K + Sbjct: 971 LKIEIIPLKSKVESNENEFIYKNDEEEEVKENADKQEIQNLREEVAKLNDILSRKPSDEY 1030 Query: 1027 ALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQI--- 1083 NQ N S ++ ++K+A+ E + + ++ + ++ EEL+ Sbjct: 1031 IENQL--NTINSQKQLIDRLQTKVAKLKNSANYSESDDESKTQTKSERNENPEELKTEVE 1088 Query: 1084 LVREQ------DDQIKELKETKLTFEMNIPKTEGMI--ISSTIEPMSDDANNVDXXXXXX 1135 L+R Q +D +K+LKET + I + + I + S IE ANN + Sbjct: 1089 LLRLQLSKLPTEDDMKKLKETIQEKDDKISELQNHITNLKSKIENYVQMANNSNKDNDDK 1148 Query: 1136 XXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQ 1195 + ++EE E +V L + +E K+++ ++ EL + ++Q Sbjct: 1149 ENDYQYEEYDDDEEVKVEGNVKSRDVVILGNDEEE-EIKVVEGKS---ELEDENENLKKQ 1204 Query: 1196 INQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEH 1255 I+ LK++L L E+DN S+ +E D++ + + ++ L+Q+E + Q Sbjct: 1205 IDDLKNQLRNLQKESDNSTSSDSES--------DEKQNQKEKDTEEKLSQKEEENQL--- 1253 Query: 1256 ELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYAD 1315 L+ ++S E K QL ++Q+ EE +E + + KL + E L++ + Sbjct: 1254 -LKAKISELEEKENQLKITLQNKHSEED-----LENIKNEVQKLNQENEILKSKIDDQQK 1307 Query: 1316 VINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENA 1375 +I IE+ + ++++ L+ E ++ K E+S + + ++ Sbjct: 1308 II--IELSNTAQNEQEL---NDLKSENNKNQLLITSLQQEIENLKAKNEKSSSSSSSDDE 1362 Query: 1376 QLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFE 1435 + K +E + E + KDSEI E T+RN+ Sbjct: 1363 KENKDEEIEILKKEIETLNGTISEKQNFETL--ISEKDSEIESLKKEIQSIETERNNNLS 1420 Query: 1436 NVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHY--ETMQKESEIERVKLIEELNV 1493 Q++ +K IE + +K + +LK+ + E + + E+ EE++ Sbjct: 1421 GKEQEIENLKKEIETMKSDKSDSESEEKLKLEDQIKQKDEEIGRLQKELSEKPSNEEISE 1480 Query: 1494 KITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQN 1545 +I + ++ ++L L + NE++ LE +E ++++ EI NL++ Sbjct: 1481 QIQTILKQGEENSKLQSQLLSMTSMVNEIKAQLEQKENLVISMETEIQNLKS 1532 Score = 140 bits (340), Expect = 2e-31 Identities = 267/1334 (20%), Positives = 554/1334 (41%), Gaps = 112/1334 (8%) Query: 303 SCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSP 362 SC E E+ ++ +++ K + L I NKE+ N+L + P Sbjct: 185 SCISIVEYLEQ-NIRKKDLSSSPKHDRSISELQAIIDLRNKEI-NELRIQLDDQNKNGKP 242 Query: 363 SKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLV 422 K+ L+S+ + NT K++ + +S+ N + NK+ +++LE+ LN + Sbjct: 243 DKEKEILLSQLTELNT--KLQKAEQEYNSKLNNLLIENNTNKSNLSQLELKNTQLNNENS 300 Query: 423 DKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLI-HVGTNTEDVNEI--A 479 + +SE + ++ + + +I + E + I A Sbjct: 301 QLKKDLSEFSKTLTSKELEASNLRDQLKKVSESNTNREDSKQIISQLQDQAEQLRNIIKA 360 Query: 480 KVQEQLKQELNDEIKDVNVKDLIEKL-KSAEEQITQLNDEIDAANKNMIKVKSNHKLKLK 538 K E K E ++ + + I KL KS+++QIT+++ E NM K+++ +L + Sbjct: 361 KEDENKKLETKNQRAALKYSEAISKLTKSSDDQITKIDQE------NM-KLQAQLQLYQQ 413 Query: 539 QMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELE-EEKGNLQLHLVDYDSGRMIESD 597 ++ K + S++SD +++ + + LS K+ ++ + + N++ + + S+ Sbjct: 414 ELSKVNASKSEISDLKEKLKEREKTIKELSSKLNDITTQSEANMEFERQKDRQIQNLHSE 473 Query: 598 VYKKMIEMENL------AETRLKAISLLESQKFDLVQE----LHILQQKYDEVED--KLA 645 V K ++E + AE K + L+ +K +L ++ + LQQK + + + +L Sbjct: 474 VAKLLVEQQKSEVIKIEAEKNRKLVKALKKEKVELDKKSQEVIAKLQQKINILTNNYELI 533 Query: 646 DISQLQSDQ-VCSEIKSVHLEEQIDALSASKK--ELALVIENLKLDKEQLYGTIKDLEND 702 + +++ +Q + S + SV E S+K +L+ ++ LK + L + L+ND Sbjct: 534 SLEKIKMEQTMSSNLLSVRKESSDTNTYLSEKVTQLSNSLQELKKQNKSLKRKLNGLQND 593 Query: 703 KEDIMN---KLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQE 759 ++ + +++ EN D KL KI E + + G+ Sbjct: 594 YNELKSNQVEIEELENENKDRKKKLRSYQNNLTPVKSPKIEDENKELKKKLRGLQNDYNL 653 Query: 760 -RDLYIENIESELSKYKSRICR-LEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYT 817 +D EN E K R+ + L +S ED E ++ +E +K + Sbjct: 654 LKDQITENDEENKQKMIRRLTKKLGQSEKQFEDVSKEREVLLARIEDLSEENEKLRNRSN 713 Query: 818 IQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYN 877 + E+V A L+ +++Q+ + + + K+Q + +Q + + ++ Sbjct: 714 EGDAEIVKTQADLISK---LQQQIQSLSNNPLDFSAKDQYINSLHQEIDELKQRLNENAA 770 Query: 878 ALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIE 937 +V +R + E E T D + +++E ED E T+ Sbjct: 771 KVVTPQDRNAVPEKEKTIIDMINEDSDG-------------YSEEEEAEDSGSEAATKDL 817 Query: 938 SAIRDKKVLNEKYEKNIEY--VTQLEAQLQEYKNNIENLNMNVEELNKMNLE--LIDKHV 993 R + + E N E +T L+ L+E N + +L + E N NLE L +K Sbjct: 818 VPSRQRMIRLSYDEPNTENAEITSLKVMLEEKTNEVNDLKKQINEANDKNLEEKLNEKVT 877 Query: 994 QKQQTQS--PDYTEQYINEINKLNA---LLKQKDEEIIALNQKINNAQVSYMSMVSDYES 1048 + T S D ++ +EIN+L LK K E +IA N IN + +Y+ Sbjct: 878 DLKSTLSLKDDIIQRQNDEINELKTHIDSLKSKIENLIATNN-INQKETEN----KEYDY 932 Query: 1049 KLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPK 1108 + + +N ++M K++ S N+EL+ L E D+ E+ K E N + Sbjct: 933 SETEQNNEDKNDIDKM--FEKKI--SNAENQELEELKAENDNLKIEIIPLKSKVESN--E 986 Query: 1109 TEGMIISSTIEPMSDDANN--VDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNT 1166 E + + E + ++A+ + L + +E+I+ + +L Sbjct: 987 NEFIYKNDEEEEVKENADKQEIQNLREEVAKLNDILSRKPSDEYIENQLNTINSQKQLID 1046 Query: 1167 ELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSS--- 1223 LQ TK+ +L+ D + ++ E+L TE + L +++L + Sbjct: 1047 RLQ---TKVAKLKNSANYSESDDESKTQTKSERNENPEELKTEVELLRLQLSKLPTEDDM 1103 Query: 1224 --ISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLD-SVQSSTQ 1280 + + ++ +I+EL + H+ ++ K E+ +++ ++ + ++ D + Sbjct: 1104 KKLKETIQEKDDKISEL-QNHITNLKS---KIENYVQMANNSNKDNDDKENDYQYEEYDD 1159 Query: 1281 EETNKI---VTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXX 1337 +E K+ V V L N D+EE ++ ++ K +++ ++ E L+ +I+D K Sbjct: 1160 DEEVKVEGNVKSRDVVILGN---DEEEEIKVVEGK-SELEDENENLKKQIDDLKNQLRNL 1215 Query: 1338 XXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVND 1397 +NQ K +E+ L+ EE QL K+ ++++ Sbjct: 1216 QKESDNSTSSDSESDEKQNQKEKDTEEK--LSQKEEENQLLKA-------------KISE 1260 Query: 1398 AEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKES 1457 E K +L L+ K SE + + + N E E ++ ++ + +K I +L+ ++ Sbjct: 1261 LEEKENQLKITLQNKHSE--EDLENIKNEVQKLNQENEILKSKIDDQQKIIIELSNTAQN 1318 Query: 1458 ELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVA 1517 E + LK N N + EIE +K E + + S + E + L++E+ Sbjct: 1319 EQELNDLKSENNKNQLLITSLQQEIENLKAKNEKSSSSSSSDDEKENKDEEIEILKKEIE 1378 Query: 1518 KTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMN 1577 N + +N E I + EI +L+ +++ ++ ++S + ++++ TM Sbjct: 1379 TLNGTISEKQNFETLISEKDSEIESLKKEIQSIETERNNNLSGKEQEIENLKKEIE-TMK 1437 Query: 1578 KELLDAVPRAELDL 1591 + D+ +L L Sbjct: 1438 SDKSDSESEEKLKL 1451 Score = 113 bits (273), Expect = 3e-23 Identities = 284/1504 (18%), Positives = 628/1504 (41%), Gaps = 135/1504 (8%) Query: 141 LGDVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXX 200 L +T L+ +++ + + + I T ++ K+ + +N Sbjct: 250 LSQLTELNTKLQKAEQEYNSKLNNLLIENNTNKSNLSQLELKNTQLNNENSQLKKDLSEF 309 Query: 201 XXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLL 260 + + Q+ K+ E+ E + K +L E I + E+ NK L Sbjct: 310 SKTLTSKELEASNLRDQLKKVSESNTNRE-DSKQIISQLQDQAEQLRNIIKAKEDENKKL 368 Query: 261 EAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIAN 320 E +L++S+ +L + + ++ +E +++ S EI++ Sbjct: 369 ETKNQRAALKYSEAISKLTKSSDDQITKIDQENMKLQAQLQLYQQELSKVNASKS-EISD 427 Query: 321 MTELTKKIE-LLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTA 379 + E K+ E ++ L+ ++ + E + + + + + + + L+ + ++ Sbjct: 428 LKEKLKEREKTIKELSSKLNDITTQSEANMEFERQKDRQIQNLHSEVAKLLVEQQ-KSEV 486 Query: 380 SKMKSPWSQLSSETLNQDT---DKKINKNEIAKLEMVIQSL--NKDLVDKEYVISEKDTX 434 K+++ ++ + L ++ DKK ++ IAKL+ I L N +L+ E + E+ Sbjct: 487 IKIEAEKNRKLVKALKKEKVELDKK-SQEVIAKLQQKINILTNNYELISLEKIKMEQTMS 545 Query: 435 XXXXXXXXXGKDT------LIAQLQLEHQQHMEGPSLIHVGTN--TEDVNEIAKVQEQLK 486 DT + QL Q+ + + N D NE+ Q ++ Sbjct: 546 SNLLSVRKESSDTNTYLSEKVTQLSNSLQELKKQNKSLKRKLNGLQNDYNELKSNQVEI- 604 Query: 487 QELNDEIKDVNVKDLIEKLKSAEEQITQLND-EIDAANKNMIKVKSNHKLKLKQMQKTI- 544 +EL +E KD +KL+S + +T + +I+ NK + K KL+ Q + Sbjct: 605 EELENENKDRK-----KKLRSYQNNLTPVKSPKIEDENKELKK-----KLRGLQNDYNLL 654 Query: 545 -DNFSKVSDSNKE--IVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDS------GRMIE 595 D ++ + NK+ I RLT++L ++ ++ +E+ L + D R E Sbjct: 655 KDQITENDEENKQKMIRRLTKKLGQSEKQFEDVSKEREVLLARIEDLSEENEKLRNRSNE 714 Query: 596 SD--VYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSD 653 D + K ++ + + +++++S Q ++ L Q+ DE++ +L ++ + Sbjct: 715 GDAEIVKTQADLISKLQQQIQSLSNNPLDFSAKDQYINSLHQEIDELKQRL---NENAAK 771 Query: 654 QVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMN-KLQN 712 V + ++ E++ + ++ E + + KDL ++ ++ Sbjct: 772 VVTPQDRNAVPEKEKTIIDMINEDSDGYSEEEEAEDSGSEAATKDLVPSRQRMIRLSYDE 831 Query: 713 YIQENMDLTDKLEKMSAEKISEL--LAKINHEEQSKIQTQFGIDAKIQERDLYIENIESE 770 EN ++T L+ M EK +E+ L K +E K ++ K+ E+ + +++S Sbjct: 832 PNTENAEITS-LKVMLEEKTNEVNDLKKQINEANDK-----NLEEKLNEK---VTDLKST 882 Query: 771 LSKYKSRICRLEESIAVMEDRRYSLERKADQL--GSYLQEKQKAYSEYTIQEDELVNRLA 828 LS I R + I ++ SL+ K + L + + +K+ EY E E N Sbjct: 883 LSLKDDIIQRQNDEINELKTHIDSLKSKIENLIATNNINQKETENKEYDYSETEQNNEDK 942 Query: 829 VLMDHDRVVEKQLLEIEHEN-KELQKKNQIL----------LEENQNLQISLSDMQQHYN 877 D D++ EK++ E++ +EL+ +N L +E N+N I +D ++ Sbjct: 943 --NDIDKMFEKKISNAENQELEELKAENDNLKIEIIPLKSKVESNENEFIYKNDEEEEVK 1000 Query: 878 ALVEKANRTDLAESESTKYQTQLRD-----LESNLKRITHEHQTLIVQKKKEIEDLEIEF 932 +K +L E + R +E+ L I + Q LI + + ++ L+ Sbjct: 1001 ENADKQEIQNLREEVAKLNDILSRKPSDEYIENQLNTINSQKQ-LIDRLQTKVAKLKNSA 1059 Query: 933 N---TQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEY--KNNIENLNMNVEELNKMNLE 987 N + ES + K NE E+ V L QL + +++++ L ++E + E Sbjct: 1060 NYSESDDESKTQTKSERNENPEELKTEVELLRLQLSKLPTEDDMKKLKETIQEKDDKISE 1119 Query: 988 LIDKHVQKQQTQSPDYTEQYINEINKLN-------ALLKQKDEEIIALNQKINNAQVSYM 1040 L H+ +++ +Y Q N NK N + D+E + + + + V + Sbjct: 1120 L-QNHITNLKSKIENYV-QMANNSNKDNDDKENDYQYEEYDDDEEVKVEGNVKSRDVVIL 1177 Query: 1041 SMVSDYESKLAQFTTKLE----NMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELK 1096 + E K+ + ++LE N+++++ + QL + ++ ++ E D++ + K Sbjct: 1178 GNDEEEEIKVVEGKSELEDENENLKKQIDDLKNQLRNLQKESDNSTSSDSESDEKQNQ-K 1236 Query: 1097 ETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSV 1156 E +++ + E ++ + I + + N + L+ + EE ++ Sbjct: 1237 EKDTEEKLSQKEEENQLLKAKISELEEKENQLKIT----------LQNKHSEEDLEN--- 1283 Query: 1157 LQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLST 1216 ++ + KLN E + +KI + + EL+ + N++++N LKS+ N +N L+++ Sbjct: 1284 IKNEVQKLNQENEILKSKIDDQQKIIIELS-NTAQNEQELNDLKSE----NNKNQLLITS 1338 Query: 1217 VAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQ 1276 + + ++ + ++ + ++ E + K E E + + +E L+ Sbjct: 1339 LQQEIENLKAKNEKSSSSSSSDDEKENKDEEIEILKKEIETLNGTISEKQNFETLISEKD 1398 Query: 1277 SSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIE-DEKVAFX 1335 S + +I ++E T N L KE+ + NL+++ I ++ +S+ E +EK+ Sbjct: 1399 SEIESLKKEIQSIE--TERNNNLSGKEQEIENLKKE----IETMKSDKSDSESEEKLKLE 1452 Query: 1336 XXXXXXXXXXXXXXXDLRTENQSYKQMQEQ--SILNINEENAQLKKSSXXXXXXXXXXXX 1393 +L +E S +++ EQ +IL EEN++L+ Sbjct: 1453 DQIKQKDEEIGRLQKEL-SEKPSNEEISEQIQTILKQGEENSKLQSQLLSMTSMVNEIKA 1511 Query: 1394 RVNDAEAKVLELTHQLE-LKD-SEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDL 1451 ++ E V+ + +++ LK S+ Q + L ++N+EF +Q+ ++ I+ L Sbjct: 1512 QLEQKENLVISMETEIQNLKSKSDNDQLSLLENENLKKQNEEFS---KQISLKDEEIQTL 1568 Query: 1452 TYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKA 1511 E E I + K N + +K + E +E+ N ++ +S E+N Sbjct: 1569 RNEIEK---INKEKDEILKNQIQESEKSDKSEANSDLEKENAELKRKLSEYSTQEEMNDQ 1625 Query: 1512 LEEEVAKTNEMQTALENQEIEIVT-LNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDE 1570 ++ ++++ E+ ++ Q + + T +N+E Q+ S K + K+ DE Sbjct: 1626 IQTILSQSEEIDK-MKKQILALTTKINEENQAKQSDEETESLKKENQTLKEELAKKPSDE 1684 Query: 1571 QLDN 1574 +L++ Sbjct: 1685 ELND 1688 Score = 112 bits (269), Expect = 9e-23 Identities = 240/1260 (19%), Positives = 519/1260 (41%), Gaps = 117/1260 (9%) Query: 145 THLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINE----KDQIIEAKNKATTXXXXXX 200 T+LS + + N+L L+ + K ++ + LQ NE + +I E +N+ Sbjct: 560 TYLSEKVTQLSNSLQELKKQNKSLKRKLNGLQNDYNELKSNQVEIEELENENKDRKKKLR 619 Query: 201 XXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLK-DIESKDVRISSLEEANKL 259 + + ++++ ++ ++ K ++ + D E+K I L + Sbjct: 620 SYQNNLTPVKSPKIEDENKELKKKLRGLQNDYNLLKDQITENDEENKQKMIRRLTKKLGQ 679 Query: 260 LEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIA 319 E ++S E L +E + ++ + ++++++ Sbjct: 680 SEKQFEDVSKEREVLLARIEDLSEENEKLRNRSNEGDAEIVKTQADLISKLQQQIQSLSN 739 Query: 320 NMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGS--PLISRKS-GR 376 N + + K + + L+ +I + + L A + T + P K+ + +I+ S G Sbjct: 740 NPLDFSAKDQYINSLHQEIDELKQRLNENAAKVVTPQDRNAVPEKEKTIIDMINEDSDGY 799 Query: 377 NTASKMKSPWSQLSSETLNQDTDKKINKN---------EIAKLEMVIQSLNKDLVDKEYV 427 + + + S+ +++ L + I + EI L+++++ ++ D + Sbjct: 800 SEEEEAEDSGSEAATKDLVPSRQRMIRLSYDEPNTENAEITSLKVMLEEKTNEVNDLKKQ 859 Query: 428 ISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQ 487 I+E + D L + L L+ + +++NE+ + LK Sbjct: 860 INEANDKNLEEKLNEKVTD-LKSTLSLKDDI---------IQRQNDEINELKTHIDSLKS 909 Query: 488 ELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMI--KVKSNHKLKLKQMQKTID 545 ++ + I N+ + K + T+ N+E M K+ + +L++++ D Sbjct: 910 KIENLIATNNINQKETENKEYDYSETEQNNEDKNDIDKMFEKKISNAENQELEELKAEND 969 Query: 546 NF--------SKVSDSNKEIVRLTEELHHLS-----QKVAELEEEKGNLQLHLVDYDSGR 592 N SKV + E + +E + Q++ L EE L L S Sbjct: 970 NLKIEIIPLKSKVESNENEFIYKNDEEEEVKENADKQEIQNLREEVAKLNDILSRKPSDE 1029 Query: 593 MIESDV-----YKKMIEMENLAETRLK-AISLLESQKFDLVQELHILQQKYDEVEDKLAD 646 IE+ + K++I+ +LK + + ES Q + +E++ ++ + Sbjct: 1030 YIENQLNTINSQKQLIDRLQTKVAKLKNSANYSESDDESKTQTKSERNENPEELKTEV-E 1088 Query: 647 ISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDI 706 + +LQ ++ +E L+E I EL I NLK E + D +D Sbjct: 1089 LLRLQLSKLPTEDDMKKLKETIQEKDDKISELQNHITNLKSKIENYVQMANNSNKDNDDK 1148 Query: 707 MNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIEN 766 N Q Y + + D K+E + +L EE ++ + ++ + + I++ Sbjct: 1149 ENDYQ-YEEYDDDEEVKVEGNVKSRDVVILGNDEEEEIKVVEGKSELEDENENLKKQIDD 1207 Query: 767 IESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNR 826 ++++L + S + ++++ E+ ++ S +E+ + + +E N+ Sbjct: 1208 LKNQLRNLQKESDNSTSSDSESDEKQNQKEKDTEEKLSQKEEENQLLKAKISELEEKENQ 1267 Query: 827 LAVLMDHDRVVEKQLLEIEHENKELQKKNQIL---LEENQNLQISLSDM---QQHYNALV 880 L + + + E+ L I++E ++L ++N+IL +++ Q + I LS+ +Q N L Sbjct: 1268 LKITLQNKHS-EEDLENIKNEVQKLNQENEILKSKIDDQQKIIIELSNTAQNEQELNDLK 1326 Query: 881 EKANRTDLA------ESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLE--IEF 932 + N+ L E E+ K + + S+ I KKEIE L I Sbjct: 1327 SENNKNQLLITSLQQEIENLKAKNEKSSSSSSSDDEKENKDEEIEILKKEIETLNGTISE 1386 Query: 933 NTQIESAIRDKKVLNEKYEKNIEYV-TQLEAQLQEYKNNIENLNMNVEEL--------NK 983 E+ I +K E +K I+ + T+ L + IENL +E + ++ Sbjct: 1387 KQNFETLISEKDSEIESLKKEIQSIETERNNNLSGKEQEIENLKKEIETMKSDKSDSESE 1446 Query: 984 MNLELIDKHVQKQQT---QSPDYTEQYINE--INKLNALLKQKDEEIIALNQKINNAQVS 1038 L+L D+ QK + + +E+ NE ++ +LKQ +E N K+ + +S Sbjct: 1447 EKLKLEDQIKQKDEEIGRLQKELSEKPSNEEISEQIQTILKQGEE-----NSKLQSQLLS 1501 Query: 1039 YMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKET 1098 SMV++ +++L Q + +ME E+Q L SK N++L +L +++ +K+ E Sbjct: 1502 MTSMVNEIKAQLEQKENLVISMETEIQN-----LKSKSDNDQLSLL---ENENLKKQNE- 1552 Query: 1099 KLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQ 1158 + + ++++ E + + IE ++ + + + ++ E+ + + S L+ Sbjct: 1553 EFSKQISLKDEEIQTLRNEIEKINKEKDEI---------LKNQIQESEKSDKSEANSDLE 1603 Query: 1159 EQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQ-EQINQLKSKLEQLNTE--NDNLLS 1215 +++A+L +L E T+ E +N ++ +++Q E+I+++K ++ L T+ +N Sbjct: 1604 KENAELKRKLSEYSTQ----EEMNDQI--QTILSQSEEIDKMKKQILALTTKINEENQAK 1657 Query: 1216 TVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSV 1275 E S+ E+A+ + T+ E +L K +++S Sbjct: 1658 QSDEETESLKKENQTLKEELAKKPSDEELNDQIQTIMTQSEELDKLRKQIVKLTAMVNSA 1717 Query: 1276 QSSTQEETNKIVTME-----QVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDE 1330 + ++ NK + E Q +S + DKE+ N+ E D N EI E+E E Sbjct: 1718 PKMSPDDENKKIYDEKDEEKQKSSSSSSSSDKEDEKENVDEIKKDDENDNEI-EKEVEKE 1776 >UniRef50_UPI00006CB352 Cluster: Viral A-type inclusion protein repeat containing protein; n=1; Tetrahymena thermophila SB210|Rep: Viral A-type inclusion protein repeat containing protein - Tetrahymena thermophila SB210 Length = 3714 Score = 169 bits (411), Expect = 5e-40 Identities = 278/1499 (18%), Positives = 661/1499 (44%), Gaps = 130/1499 (8%) Query: 144 VTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXX 203 + LS + ++ + L+V++ +T I LQ+++N+ ++ + KN+ Sbjct: 1385 IDQLSAKVGKQQKQVEDLEVQLSETQTKIKQLQDQVNDLEEQKQNKNEKLQEKEKELFAV 1444 Query: 204 XXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAA 263 ++ + Q+ ++ +E D Q+ L IE K+ + ++E E + Sbjct: 1445 LSKSNEKEQNLENQLEDVRRKLKEVE----DNLQKALNTIEQKETELKLIKERLTKSEKS 1500 Query: 264 RFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTE 323 ++ E ++ ++E++Q L +Q+ E + + + S+ + E Sbjct: 1501 EKKLEKERNQKSEEVQQQQKDVEQLQQRVQILEQQNSEYGKIIQGKSNDYDSIIKSVHKE 1560 Query: 324 LTKKIELLE-HLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKM 382 L +IE+++ H ++ ++ + K ++K S + + + +N ++ Sbjct: 1561 LNTQIEIVQTHKTLLDKEQSEHEQTKKEFEDWKNKLQKSQEENR---LKTEEIQNIQDQL 1617 Query: 383 KSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVD-KEYVISEKDTXXXXXXXX 441 ++++S+ ++T K +N N+ L+ + LN++ + K + S + Sbjct: 1618 IDTQNEINSQ---EETIKNLN-NQYENLQKQNEQLNEEHNNLKSKLTSLNEEYSFKIIRM 1673 Query: 442 XXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDE--IKDVNVK 499 TL +L Q + + LI N +N I K+ + +Q +N + I+D + Sbjct: 1674 EETIKTLEEELNQLKQNNYDLQQLIQEKDNLIQIN-ITKINQYEQQIINFQEIIQDQQDQ 1732 Query: 500 DLIEK------LKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDS 553 I+K ++ E + + N+++ A + + VK N + ++T +F + Sbjct: 1733 AQIQKQQIELQAQTQESTLKKQNEQVIAQIRAEL-VKENLQNIQNCKEETEIHFQNILQE 1791 Query: 554 NKEI--VRLTEELHHLSQKVAELEEE-KGNLQLHLVDYDSGRMIESDVYKKMIEMENLAE 610 ++ V + K+ +++E + LQ L + ++ + + + +K+ E E + Sbjct: 1792 KEQQYQVLFQQTTQSYESKIILIQQEFQVILQQKLEELEAAQ--SAILQQKLNEQEAQHQ 1849 Query: 611 TRLKAISLLESQKFDLV----QELHILQQKYDE-VEDKLADISQLQSDQVCSEIKSVHLE 665 L+ LL++Q+ +L +E+ L+ +Y E + ++ + +++ S+Q +I++ + Sbjct: 1850 KELQ--KLLKNQQNELQSKFQEEMKHLEAQYQEKLNEQSENHNKILSEQA-KQIQNSENQ 1906 Query: 666 EQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQEN-MDLTDKL 724 + + + ++ + E+++ I L+ ++ Q +QE +++ ++ Sbjct: 1907 NLSQKIIDQQTQFEQILSQKLKESEEIHNQI--LQEKIKECEGNFQLILQEKTIEIQNEQ 1964 Query: 725 EKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEES 784 K+ +K+ E +++N + Q K+ F Q+ +E + + Y I ++ Sbjct: 1965 NKVLLDKLKEQESQLNKQIQQKLSADFQ-----QQVQTLVEKQKQQEENYNKIIQEKDQQ 2019 Query: 785 IAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEI 844 IA M++ L+ + + LQEK+ E T N + ++ + + Q+ +I Sbjct: 2020 IAKMDE---ILKVNSQEFQQVLQEKEAQILEIT-------NNINIIQQQNNI---QIQQI 2066 Query: 845 EHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRT---DLAESESTKYQTQLR 901 ++K Q+ N+I+ +N+ + + S Q ++ +R + + E K + ++ Sbjct: 2067 NQQHK--QEINEIVSSKNEITKYTKSLEDQIAEQEMKNKDRDQEENQLKQELKKQEDKVH 2124 Query: 902 DLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLE 961 DL ++ E + L Q + ++ L+ + I++ D + LNE + + L+ Sbjct: 2125 DLTQKYSKLQTELENLKEQHQDYVKQLQNQHLQAIQAKDSDIEKLNENVRNSKKNSQDLQ 2184 Query: 962 AQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTE--QYINEIN-KLNALL 1018 QLQ + NL + EL +N + ++ Q+ +Y+E Q + + N + +L Sbjct: 2185 LQLQSLQQTRHNLEEQLNELRTLNSKSANQQSQQFSQLQDEYSELQQNLQQKNLQFKQML 2244 Query: 1019 KQKDEEIIALNQKINNAQVSY---MSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSK 1075 + + E LN+KI + ++ ++++ + Q K++ +++++ Q+ + Sbjct: 2245 NEHESEKSQLNEKITKIEKQLKDNQTICQEHQNLIEQNNLKIKEQQQKIKEYENQISQMQ 2304 Query: 1076 QHNEE-LQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXX 1134 Q NEE +I +EQ++ KE+++ K E N K I+ + +N+ Sbjct: 2305 QQNEEQAKIQQKEQNNLDKEIEKLKKHIESN-QKEAAEQQQELIKKHQQEIDNIQNQNDI 2363 Query: 1135 XXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQE 1194 Q+ E IQ+ + Q++ A+ + + E + IQ T + ++V Q Sbjct: 2364 HLQQQLNQLKQQYEVQIQQITKQQKEEAQKHNQSSE---QQIQQITAKYQQDIQNIVQQN 2420 Query: 1195 -----QINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREAD 1249 ++N+ +L Q +++N + + + + S+ + + E ++++++ ++Q Sbjct: 2421 EQKIAELNEANKQLSQKDSDNQIKIHQLQQESENNSTNFETKISENSKIYEEKISQISIT 2480 Query: 1250 FQKTEHELR----VQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEH 1305 F+ E++ +Q++ + +YE + S+Q S +++TN+ E+ L +KL KEE Sbjct: 2481 FETKITEIKQSYEIQINELKQQYETKIQSLQES-EKQTNESSNKEK-QELISKL--KEEF 2536 Query: 1306 LRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQ-SYKQMQE 1364 + + EK + Q++ ++ ++ + + + + +++ + K++ E Sbjct: 2537 QKEIAEKDENHNKQVKEIQDNLDKQINDYESKIKALQVDYQKQIEESKADHEKNIKEITE 2596 Query: 1365 QSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYT 1424 + I++ N + +K D E +++ H+ +K E+ +K T Sbjct: 2597 KFEKQISDLNERQQK-----------------DIEG--IQINHEFIIK--ELQKKIETLT 2635 Query: 1425 ITLTQRNDEFEN-VRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHY---ETMQKES 1480 ITL + N E E+ V + E E+ I+++ + S++ +MH++ N Y ++ Sbjct: 2636 ITLDEINQEKEDIVNKAKEEAEQEIQNIDQKYRSQIQ----QMHKDHNDYILNTESDQQD 2691 Query: 1481 EIERVK-----LIEELNVKI-TESVSLNKQVAELNKALEEEVAKTNEMQTAL--ENQEIE 1532 I+ VK I+EL I ++S L ++ K LEE++ + + T ENQ +E Sbjct: 2692 AIQTVKEQYELEIQELKQMIPSDSNELIQKYLNQIKELEEKIQQLQQQDTQSNEENQRLE 2751 Query: 1533 IVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDL 1591 + I L+ + +K Q +S S++ + +++ T NKE + + R E +L Sbjct: 2752 LT-----IIQLEEKIIQVENKYQIQLSNESESHKQLIIEIE-TQNKEKIAELQRIENEL 2804 Score = 160 bits (389), Expect = 3e-37 Identities = 280/1403 (19%), Positives = 614/1403 (43%), Gaps = 131/1403 (9%) Query: 214 TKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEE--ANKLLEAARFEISLEH 271 +KQ M + ENF + + K++++ + K+ +++ + +E N E +++I E+ Sbjct: 385 SKQMMQEQSENFKELRKKLKEQEKIINKE---QEIIVKEMERNLKNSKDEQKKYQIQYEN 441 Query: 272 SKL-AQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIEL 330 K +++Q K +E I E+ E+ ++E Sbjct: 442 KKKEIIQIKQSLTIQINTLSQQVDSLKSENSLLKQEIQNININRQAELNEFEEVKLQLEN 501 Query: 331 LEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPL---ISRKSGRNTASKMKSPWS 387 EH Q+ Q +E + K+ + + S S L I+R + N A+ +K Sbjct: 502 AEH---QLFQIQREYQTKIEEVSEKKYENSQNHITVSQLNDQINRLNQEN-ANLLKEKEQ 557 Query: 388 QL----SSETLNQDTDKKINK-NEI-AKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXX 441 L S + ++ K++K NE+ + ++ I+ L+ L DKE I EK Sbjct: 558 VLRKSESDKMRIEEFQLKLSKVNEVQEQYQLEIRQLSVKLADKENEIYEK-MQEIDQLRQ 616 Query: 442 XXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDL 501 D I QL+ E+Q ++ + +H T ++ + ++ ++L++ L + VNV+ + Sbjct: 617 ISSNDLEIQQLKEENQNLIDQINQLHEAQQTLAIHNV-QINDELRR-LQQQ-SSVNVQQI 673 Query: 502 IEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLT 561 I + +E+ T + EI+ KN+I ++ K Q Q + NF+ K++ L Sbjct: 674 IIEKTQIQERYTYILKEIE--EKNII--IHQYEEKEDQYQAEVMNFT------KQLENLQ 723 Query: 562 EELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLES 621 E+ ++++ +L EK + + D + E ++ +K ++ + + + I Sbjct: 724 EKYDRMNEEFDDLLNEKEQFLIQIQDLQNKCQHEQEINQKY--LDQIGKYKQDDIDQQNR 781 Query: 622 QKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALV 681 +K + L +Q+ D++ D+L+ S+ + EIK++ Q ++E A + Sbjct: 782 EK----KYLKEIQKLKDDI-DQLSKQSKKNQHENNEEIKAMLTSLQTKN-EKLEQENAQI 835 Query: 682 IENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTD----KLE---KMSAEKISE 734 +++ + + QL ++ L D+ N L ++E ++ D +LE ++SA+KI Sbjct: 836 LQSSQEQQNQLLTNLEMLTQQNIDVQNNLA-ILEEEVNQKDLKIQQLEQELQLSAQKIET 894 Query: 735 LLAKINHEEQSK-IQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRY 793 L+ E + K Q Q + + Q+ ++ I+++++++ K +I ++ ++ ++ Sbjct: 895 FLSLAEEENKIKHAQNQALLKQQEQKLEIIIDDLKNKIDKLNQQI---KDQQYENKEVKF 951 Query: 794 SLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQK 853 LE+ + ++ QK + + ++ A+ + +++Q+ + E + K QK Sbjct: 952 ELEKCRESKKEQEEKLQKQKDKNKELKQKITEIEALSVKQISQLQQQISQYEIQIKNSQK 1011 Query: 854 KNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAES--------ESTKYQTQLRDLES 905 Q L ++ ++ LS Q + EK++ + +++ E KYQ Q+++L++ Sbjct: 1012 VEQDLKDKITEIKEKLSQNQLELSKQKEKSSSSSSSKNVLRSEYIQEIEKYQNQIKELKN 1071 Query: 906 NLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQ 965 NL K++E + E+N K+L+ + E+ +E +++ + Sbjct: 1072 NLD-----------DKERETRKILTEYNE------ARNKILSYQTEQ-LENEEKIDKLKE 1113 Query: 966 EYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEI 1025 E K LN E ++++ E I K + S + I++IN N+ ++ I Sbjct: 1114 ELKVKSNKLNQQQETIDQLQQE-IQKKQNIIMSGSNNLNNSQISQING-NSNQRRSLNNI 1171 Query: 1026 IALNQKINNA-QVSYMS-MVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHN-EELQ 1082 I INN VS ++ ++D ++ L + + N++EE +++ +Q +L+ Sbjct: 1172 IVDESGINNTNHVSQLNQQINDLQNLLQERENIINNLKEENKQIQDFYHSEQQEKVNQLE 1231 Query: 1083 ILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXL 1142 ++ ++QIKE ++ K+ ++ + + S I+ ++D + L Sbjct: 1232 NQYQQIENQIKE-RDDKIAYQSSQLDQK----SKEIQQLNDRIKQITSTKDQITQQYSKL 1286 Query: 1143 KVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSK 1202 QE + +++V E +AKL QE I++++ D++ Q+ +++K + Sbjct: 1287 --QENNLKLHDQNV--ELTAKLENFQQEFQKIIVKVKEQEQATNYKDMIIQQLDDKIK-E 1341 Query: 1203 LEQLNTENDNLLSTV-AELRSSISSA-VDQRGFEIAELWKQ----HLAQREADFQKTEHE 1256 LEQ E D ++ V + + ++ A Q+ + KQ L+ + QK + Sbjct: 1342 LEQEKQEADKVIDKVKSSKKDQLNDAQQQQKNLQANNEQKQALIDQLSAKVGKQQKQVED 1401 Query: 1257 LRVQLSAFESKYEQLLDSVQSSTQEETNKIVTM---------------EQVTSLQNKLQD 1301 L VQLS ++K +QL D V +++ NK + E+ +L+N+L+D Sbjct: 1402 LEVQLSETQTKIKQLQDQVNDLEEQKQNKNEKLQEKEKELFAVLSKSNEKEQNLENQLED 1461 Query: 1302 KEEHLRNLQEKYADVINQIEILRSE---IEDEKVAFXXXXXXXXXXXXXXXXDLRTENQS 1358 L+ +++ +N IE +E I++ +++ + + Sbjct: 1462 VRRKLKEVEDNLQKALNTIEQKETELKLIKERLTKSEKSEKKLEKERNQKSEEVQQQQKD 1521 Query: 1359 YKQMQE--QSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQ--LELKDS 1414 +Q+Q+ Q + N E ++ + + + + ++++ TH+ L+ + S Sbjct: 1522 VEQLQQRVQILEQQNSEYGKIIQGKSNDYDSIIKSVHKELNTQIEIVQ-THKTLLDKEQS 1580 Query: 1415 EIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYE 1474 E Q E+ + E R + E + I+D + ++E+ + N YE Sbjct: 1581 EHEQTKKEFEDWKNKLQKSQEENRLKTEEIQ-NIQDQLIDTQNEINSQEETIKNLNNQYE 1639 Query: 1475 TMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIV 1534 +QK++E +L EE N ++ SLN++ + +EE + E L+ ++ Sbjct: 1640 NLQKQNE----QLNEEHNNLKSKLTSLNEEYSFKIIRMEETIKTLEEELNQLKQNNYDLQ 1695 Query: 1535 TLNDEITNLQNMVRASSSKIQKH 1557 L I N+++ + +KI ++ Sbjct: 1696 QL---IQEKDNLIQINITKINQY 1715 Score = 152 bits (369), Expect = 7e-35 Identities = 295/1534 (19%), Positives = 639/1534 (41%), Gaps = 108/1534 (7%) Query: 90 ISESLANTLKQKEILMEKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSN 149 +++ AN LK+KE ++ K S+ I QL ++ LS Sbjct: 544 LNQENANLLKEKEQVLRK-------SESDKMRIEEFQLKLSKVNEVQEQYQL-EIRQLSV 595 Query: 150 TIKEKDNAL--SVLQV-KMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXX 206 + +K+N + + ++ +++ + + L++Q+ E +I+ N+ Sbjct: 596 KLADKENEIYEKMQEIDQLRQISSNDLEIQQLKEENQNLIDQINQLHEAQQTLAIHNVQI 655 Query: 207 XXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAA--R 264 +Q +Q+ I + + ++ +LK+IE K++ I EE +A Sbjct: 656 NDELRRLQQQSSVNVQQ-IIIEKTQIQERYTYILKEIEEKNIIIHQYEEKEDQYQAEVMN 714 Query: 265 FEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEK-----GSL--- 316 F LE+ + + + Q ++ C+ + EI +K G Sbjct: 715 FTKQLENLQEKYDRMNEEFDDLLNEKEQFLIQIQDLQNKCQHEQEINQKYLDQIGKYKQD 774 Query: 317 EIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGR 376 +I K ++ ++ L I Q +K+ + E KA+ + + + + +++ + Sbjct: 775 DIDQQNREKKYLKEIQKLKDDIDQLSKQSKKNQHENNEEIKAMLTSLQTKNEKLEQENAQ 834 Query: 377 NTASKMKSPWSQLSS-ETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXX 435 S + L++ E L Q N I + E+ + L +++E +S + Sbjct: 835 ILQSSQEQQNQLLTNLEMLTQQNIDVQNNLAILEEEVNQKDLKIQQLEQELQLSAQKIET 894 Query: 436 XXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTED-VNEIAKVQEQLKQELNDEIK 494 K L QQ + +I N D +N+ K Q+ +E+ E++ Sbjct: 895 FLSLAEEENKIKHAQNQALLKQQEQKLEIIIDDLKNKIDKLNQQIKDQQYENKEVKFELE 954 Query: 495 DV--NVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSD 552 + K+ EKL+ +++ +L +I +K S + ++ Q + I N KV Sbjct: 955 KCRESKKEQEEKLQKQKDKNKELKQKITEIEALSVKQISQLQQQISQYEIQIKNSQKVEQ 1014 Query: 553 SNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETR 612 K+ ++TE LSQ EL ++K + S ++ S+ +++ + +N Sbjct: 1015 DLKD--KITEIKEKLSQNQLELSKQK---EKSSSSSSSKNVLRSEYIQEIEKYQN----- 1064 Query: 613 LKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALS 672 I L++ D +E + +Y+E +K I Q++Q+ +E K L+E++ S Sbjct: 1065 --QIKELKNNLDDKERETRKILTEYNEARNK---ILSYQTEQLENEEKIDKLKEELKVKS 1119 Query: 673 ASKKELALVIENLK--LDKEQ--LYGTIKDLENDKEDIMNKLQNYIQE-NMDLTDKLEKM 727 + I+ L+ + K+Q + +L N + +N N + N + D+ Sbjct: 1120 NKLNQQQETIDQLQQEIQKKQNIIMSGSNNLNNSQISQINGNSNQRRSLNNIIVDESGIN 1179 Query: 728 SAEKISELLAKINHEEQSKIQTQFGIDAKIQE-----RDLYIENIESELSKYKSRICRLE 782 + +S+L +IN + Q+ +Q + I ++E +D Y + ++++ +++ ++E Sbjct: 1180 NTNHVSQLNQQIN-DLQNLLQERENIINNLKEENKQIQDFYHSEQQEKVNQLENQYQQIE 1238 Query: 783 ESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLL 842 I +D+ + DQ +Q+ + T +D++ + + L +++ + Q + Sbjct: 1239 NQIKERDDKIAYQSSQLDQKSKEIQQLNDRIKQITSTKDQITQQYSKLQENNLKLHDQNV 1298 Query: 843 EIEHENKELQKKNQ--ILLEENQNLQISLSDM--QQHYNALVEKANRTDLAESESTKYQT 898 E+ + + Q++ Q I+ + Q + DM QQ + + E A+ K ++ Sbjct: 1299 ELTAKLENFQQEFQKIIVKVKEQEQATNYKDMIIQQLDDKIKELEQEKQEADKVIDKVKS 1358 Query: 899 QLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKV-LNEKYEKNIEYV 957 +D ++ ++ Q QK+ I+ L + Q + + D +V L+E K + Sbjct: 1359 SKKDQLNDAQQQQKNLQANNEQKQALIDQLSAKVGKQ-QKQVEDLEVQLSETQTK----I 1413 Query: 958 TQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQ---TQSPDY---TEQYINEI 1011 QL+ Q+ + + +N N ++E K ++ K +K+Q Q D ++ + + Sbjct: 1414 KQLQDQVNDLEEQKQNKNEKLQEKEKELFAVLSKSNEKEQNLENQLEDVRRKLKEVEDNL 1473 Query: 1012 NKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQL 1071 K ++QK+ E+ + +++ ++ S + + K + + +++E+ QRV Sbjct: 1474 QKALNTIEQKETELKLIKERLTKSEKSEKKLEKERNQKSEEVQQQQKDVEQLQQRVQILE 1533 Query: 1072 LDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXX 1131 + ++ + +Q + D IK + + +L ++ I +T ++ + + + Sbjct: 1534 QQNSEYGKIIQGKSNDYDSIIKSVHK-ELNTQIEIVQTHKTLLD------KEQSEHEQTK 1586 Query: 1132 XXXXXXXXXXLKVQEEEEF-IQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDV 1190 K QEE +E +Q+Q E+ I L L + Sbjct: 1587 KEFEDWKNKLQKSQEENRLKTEEIQNIQDQLIDTQNEINSQEETIKNLNNQYENLQKQNE 1646 Query: 1191 VNQEQINQLKSKLEQLNTEND----NLLSTVAELRSSISSAVDQRGFEIAEL--WKQHLA 1244 E+ N LKSKL LN E + T+ L ++ + Q +++ +L K +L Sbjct: 1647 QLNEEHNNLKSKLTSLNEEYSFKIIRMEETIKTLEEELNQ-LKQNNYDLQQLIQEKDNLI 1705 Query: 1245 Q------READFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNK 1298 Q + + Q + +Q +++ ++ +Q+ TQE T K + + ++ + Sbjct: 1706 QINITKINQYEQQIINFQEIIQDQQDQAQIQKQQIELQAQTQESTLKKQNEQVIAQIRAE 1765 Query: 1299 LQDKEEHLRNLQE-KYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRT-EN 1356 L +E+L+N+Q K I+ IL+ + + +V F + + Sbjct: 1766 L--VKENLQNIQNCKEETEIHFQNILQEKEQQYQVLFQQTTQSYESKIILIQQEFQVILQ 1823 Query: 1357 QSYKQMQ--EQSIL--NINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELK 1412 Q ++++ + +IL +NE+ AQ +K E K LE +Q +L Sbjct: 1824 QKLEELEAAQSAILQQKLNEQEAQHQKELQKLLKNQQNELQSKFQEEMKHLEAQYQEKLN 1883 Query: 1413 D-SEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYE--KESE---LAILRLKM 1466 + SE + K Q N E +N+ Q++++ + + E + + KESE IL+ K+ Sbjct: 1884 EQSENHNKILSEQAKQIQ-NSENQNLSQKIIDQQTQFEQILSQKLKESEEIHNQILQEKI 1942 Query: 1467 HENANHYETMQKESEIE-RVKLIEELNVKITESVS-LNKQVAE-LNKALEEEVAKTNEMQ 1523 E +++ + +E IE + + + L K+ E S LNKQ+ + L+ +++V E Q Sbjct: 1943 KECEGNFQLILQEKTIEIQNEQNKVLLDKLKEQESQLNKQIQQKLSADFQQQVQTLVEKQ 2002 Query: 1524 TALENQEIEIVTLND-EITNLQNMVRASSSKIQK 1556 E +I+ D +I + +++ +S + Q+ Sbjct: 2003 KQQEENYNKIIQEKDQQIAKMDEILKVNSQEFQQ 2036 Score = 140 bits (338), Expect = 4e-31 Identities = 232/1276 (18%), Positives = 559/1276 (43%), Gaps = 109/1276 (8%) Query: 319 ANMTELTKKIELLEHLN-CQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRN 377 A + E+T I +++ N QI+Q N++ + ++ + + ++ +K I+ + +N Sbjct: 2043 AQILEITNNINIIQQQNNIQIQQINQQHKQEINEIVSSKNEITKYTKSLEDQIAEQEMKN 2102 Query: 378 TASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXX 437 + +QL E Q+ + +KL+ +++L + ++YV ++ Sbjct: 2103 KDRDQEE--NQLKQELKKQEDKVHDLTQKYSKLQTELENLKEQ--HQDYVKQLQNQHLQA 2158 Query: 438 XXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVN 497 KD+ I +L + + + + + + + + L+++LN E++ +N Sbjct: 2159 IQA----KDSDIEKLNENVRNSKKNSQDLQL-----QLQSLQQTRHNLEEQLN-ELRTLN 2208 Query: 498 VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEI 557 K ++ +Q +QL DE +N+ L+ KQM ++ S+ S N++I Sbjct: 2209 SKSANQQ----SQQFSQLQDEYSELQQNL----QQKNLQFKQMLN--EHESEKSQLNEKI 2258 Query: 558 VRLTEELHHLSQKVAELEE---EKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLK 614 ++ ++L +Q + + + E+ NL++ + E+ + + + E A+ + K Sbjct: 2259 TKIEKQLKD-NQTICQEHQNLIEQNNLKIK-EQQQKIKEYENQISQMQQQNEEQAKIQQK 2316 Query: 615 AISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSAS 674 + L+ + L + + Q++ E + +L Q + D + ++ +HL++Q++ L Sbjct: 2317 EQNNLDKEIEKLKKHIESNQKEAAEQQQELIKKHQQEIDNIQNQ-NDIHLQQQLNQL--- 2372 Query: 675 KKELALVIENL-KLDKEQLYGTIKDLENDKEDIMNK----LQNYIQENMDLTDKLE---K 726 K++ + I+ + K KE+ + E + I K +QN +Q+N +L K Sbjct: 2373 KQQYEVQIQQITKQQKEEAQKHNQSSEQQIQQITAKYQQDIQNIVQQNEQKIAELNEANK 2432 Query: 727 MSAEKISELLAKINHEEQSKIQTQFGIDAKIQERD-LYIENIESELSKYKSRICRLEESI 785 ++K S+ KI+ +Q + KI E +Y E I ++++I +++S Sbjct: 2433 QLSQKDSDNQIKIHQLQQESENNSTNFETKISENSKIYEEKISQISITFETKITEIKQSY 2492 Query: 786 AVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQE-DELVNRLAVLMDHDRVVEKQLLEI 844 + + L+++ + LQE +K +E + +E EL+++L + + EK Sbjct: 2493 EIQINE---LKQQYETKIQSLQESEKQTNESSNKEKQELISKLKEEFQKE-IAEKD---- 2544 Query: 845 EHENKELQKKNQILLEENQNLQISLSDMQQHYNALVE--KANRTDLAESESTKYQTQLRD 902 E+ NK++++ L ++ + + + +Q Y +E KA+ + + K++ Q+ D Sbjct: 2545 ENHNKQVKEIQDNLDKQINDYESKIKALQVDYQKQIEESKADHEKNIKEITEKFEKQISD 2604 Query: 903 L----ESNLKRITHEHQTLIVQKKKEIEDLEI---EFNTQIESAIRDKKVLNEKYEKNIE 955 L + +++ I H+ +I + +K+IE L I E N + E + K E+ +NI+ Sbjct: 2605 LNERQQKDIEGIQINHEFIIKELQKKIETLTITLDEINQEKEDIVNKAKEEAEQEIQNID 2664 Query: 956 --YVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSP----DYTEQYIN 1009 Y +Q++ +++ + I N + ++ + E + +Q+ + P + ++Y+N Sbjct: 2665 QKYRSQIQQMHKDHNDYILNTESDQQDAIQTVKEQYELEIQELKQMIPSDSNELIQKYLN 2724 Query: 1010 EINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSK 1069 +I +L ++Q ++ N++ +++ + + ++ +L N E +++ Sbjct: 2725 QIKELEEKIQQLQQQDTQSNEENQRLELTIIQLEEKIIQVENKYQIQLSNESESHKQLII 2784 Query: 1070 QL-LDSKQHNEELQILVREQDDQIKEL----KETKLTFEMNIPKTEGMIISSTIEPMSDD 1124 ++ +K+ ELQ + E QI L ++ K+ + I + +G I + + Sbjct: 2785 EIETQNKEKIAELQRIENELRIQIASLLGMDEKQKVDQQQKINQ-QGADKEQQIVILQKE 2843 Query: 1125 ANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKI-IQLETLNT 1183 + ++ L++QE E+ IQ+ +Q + ++ ++L + Y I ++ E L + Sbjct: 2844 IHTIESTYQ--------LRIQEFEKQIQD---IQLRESQRYSQLAQRYLLICLESERLKS 2892 Query: 1184 ELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRS--SISSAVDQRGFEIAELWKQ 1241 + + +Q +S++ +L + N + +++L+ +ISS + + ++++Q Sbjct: 2893 SANERNSSSGSNTSQYQSRINELEIQIQNHIEVISKLQQELNISSTTINQQIQKIQIYEQ 2952 Query: 1242 HLAQRE-ADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQ 1300 + D + L V L A + Q+ + S + +N+ V ++ + +KLQ Sbjct: 2953 QIQSNNFTDQNLLQKYLIVCLEA--ERLRQVALNQSSKSMAVSNQPVDFDKDQQI-SKLQ 3009 Query: 1301 DKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYK 1360 + + + + IN + L S++E E + Q Sbjct: 3010 IQVQQYEHKMSELLITINSKQELISKLETEINIHIEKVSILNQQMQSQQTQSSVDTQL-- 3067 Query: 1361 QMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKT 1420 +Q+ I+ + E +L+K + + + +V++L ++ K I + Sbjct: 3068 -LQKYLIVCLEAERLKLQKGTSGISIQQNFNDSEIEILKQRVIQLEQEVIYKSQIISEFE 3126 Query: 1421 HEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKES 1480 + + ++ + + + QQ + E L + + + A +EN E ++K+ Sbjct: 3127 ESKGVKRSTKSSQNQELSQQYLVVCMEAERLQQQLQKQKAD-----YENQIS-ELIKKDK 3180 Query: 1481 EIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEI 1540 + I + +K +LN+++ K+ + K+N E+Q+ +I + ++ Sbjct: 3181 RNQEYLKINDAQIK-----ALNEKL----KSSSQSSLKSNPSSPVNEDQDNKIKEIQAKL 3231 Query: 1541 TNLQNMVRASSSKIQK 1556 Q + + KI+K Sbjct: 3232 EKAQMQIESQMQKIEK 3247 Score = 122 bits (293), Expect = 1e-25 Identities = 276/1384 (19%), Positives = 609/1384 (44%), Gaps = 129/1384 (9%) Query: 214 TKQQMTKMQENFIAMEAEWKDEKQRLLKDIES----KDVRISSLEEANKLLEAARFEISL 269 TKQQ + Q++ + E + + + +DI++ + +I+ L EANK L + + Sbjct: 2384 TKQQKEEAQKHNQSSEQQIQQITAKYQQDIQNIVQQNEQKIAELNEANKQLSQKDSDNQI 2443 Query: 270 EHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIE 329 + +L QE E + E E ++I E+ +I+ +T TK E Sbjct: 2444 KIHQLQQESENNST---------------NFETKISENSKIYEEKISQIS-ITFETKITE 2487 Query: 330 LLEHLNCQIRQTNKELENKLATMGTESKAVS-SPSKKGSPLISR---KSGRNTASKMKSP 385 + + QI + ++ E K+ ++ K + S +K+ LIS+ + + A K ++ Sbjct: 2488 IKQSYEIQINELKQQYETKIQSLQESEKQTNESSNKEKQELISKLKEEFQKEIAEKDENH 2547 Query: 386 WSQLSSETLNQDTDKKIN--KNEIAKLEMVIQS-LNKDLVDKEY---VISEKDTXXXXXX 439 Q+ + + DK+IN +++I L++ Q + + D E I+EK Sbjct: 2548 NKQVKE--IQDNLDKQINDYESKIKALQVDYQKQIEESKADHEKNIKEITEKFEKQISDL 2605 Query: 440 XXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVK 499 KD I +Q+ H+ ++ + T T ++EI + +E + + +E + ++ Sbjct: 2606 NERQQKD--IEGIQINHEFIIKELQK-KIETLTITLDEINQEKEDIVNKAKEEAEQ-EIQ 2661 Query: 500 DLIEKLKSAEEQITQ------LNDEIDAANKNMIKVKSNHKLKLKQMQKTI--DNFSKVS 551 ++ +K +S +Q+ + LN E D + + VK ++L+++++++ I D+ + Sbjct: 2662 NIDQKYRSQIQQMHKDHNDYILNTESDQQDA-IQTVKEQYELEIQELKQMIPSDSNELIQ 2720 Query: 552 DSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAET 611 +I L E++ L Q+ + EE L+L ++ + ++I+ + K I++ N +E+ Sbjct: 2721 KYLNQIKELEEKIQQLQQQDTQSNEENQRLELTIIQLEE-KIIQVE-NKYQIQLSNESES 2778 Query: 612 RLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLE--EQID 669 + I +E+Q + + EL ++ +E+ ++A + + Q + + ++ + ++ Sbjct: 2779 HKQLIIEIETQNKEKIAELQRIE---NELRIQIASLLGMDEKQKVDQQQKINQQGADKEQ 2835 Query: 670 ALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKL-QNYIQENMDLTDKLEKMS 728 + +KE+ + +L ++ I+D++ + ++L Q Y+ ++ +++L K S Sbjct: 2836 QIVILQKEIHTIESTYQLRIQEFEKQIQDIQLRESQRYSQLAQRYLLICLE-SERL-KSS 2893 Query: 729 AEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVM 788 A + + + QS+I ++ +IQ I ++ EL+ + I + + I + Sbjct: 2894 ANERNSSSGSNTSQYQSRINE---LEIQIQNHIEVISKLQQELNISSTTINQQIQKIQIY 2950 Query: 789 EDRRYSLERKADQ--LGSYL-----QEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQL 841 E + S DQ L YL E+ + + + V+ V D D+ + K Sbjct: 2951 EQQIQS-NNFTDQNLLQKYLIVCLEAERLRQVALNQSSKSMAVSNQPVDFDKDQQISK-- 3007 Query: 842 LEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKAN-RTDLAESESTKYQTQL 900 L+I+ + E K +++L+ N ++ +S ++ N +EK + +S+ T+ Sbjct: 3008 LQIQVQQYE-HKMSELLITINSKQEL-ISKLETEINIHIEKVSILNQQMQSQQTQSSVDT 3065 Query: 901 RDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQL 960 + L+ L + E + L +QK ++ FN E I ++V+ + E+ + Y +Q+ Sbjct: 3066 QLLQKYLI-VCLEAERLKLQKGTSGISIQQNFNDS-EIEILKQRVI--QLEQEVIYKSQI 3121 Query: 961 EAQLQEYKNNIENLNMNV-EELNK------MNLELIDKHVQKQQTQSPDYTEQYINEINK 1013 ++ +E K + + +EL++ M E + + +QKQ+ + + I + + Sbjct: 3122 ISEFEESKGVKRSTKSSQNQELSQQYLVVCMEAERLQQQLQKQKADYENQISELIKKDKR 3181 Query: 1014 LNALLKQKDEEIIALNQKI-NNAQVSYMSMVS-----DYESKLAQFTTKLENMEEEMQRV 1067 LK D +I ALN+K+ +++Q S S S D ++K+ + KLE + +MQ Sbjct: 3182 NQEYLKINDAQIKALNEKLKSSSQSSLKSNPSSPVNEDQDNKIKEIQAKLE--KAQMQIE 3239 Query: 1068 SKQLLDSKQHNEELQILVREQDDQ--IKELKETKLTFEMNIPKTEGMII--SSTIEPMSD 1123 S+ K HNE++ + + I +LK+ K + E + + E I S IE + Sbjct: 3240 SQMQKIEKLHNEKINVEDSNANLNRFINDLKDQKSSIEKQLHQLEKENIEKSHQIEKLEQ 3299 Query: 1124 DANNVDXXXXXXXXXXXXLKVQ--EEEEFIQERSVLQEQSAKLN---TELQECYTKIIQL 1178 + + +++Q +EEE+ + V+ + L T+L+ K + Sbjct: 3300 EKILLQKSVEELGEKLIKMQIQQRDEEEYDDQVFVVNRKMDALKSLVTQLERDVKKYV-- 3357 Query: 1179 ETLNT-ELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAE 1237 ET T + G + + ++ L++ +EQL T+N N ++ + +D + ++ + Sbjct: 3358 ETSQTMQRIGISLFSVDRDLPLETFVEQL-TQNVN------DVLKFLEQQIDDKDAQLED 3410 Query: 1238 LWKQHLAQREADFQ-KTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQ 1296 L + A+ + +Q + H+ F++ ++ ++ V +EQ Q Sbjct: 3411 LQRNLQAKDDQIYQLQNNHQQSFLQKEFQTGEDKNMEKVNEILGLSAIGADIVEQKKD-Q 3469 Query: 1297 NKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTEN 1356 + L D + +++K V QI ++ E+ + + +++N Sbjct: 3470 SFLSDHDIENIAIEDKKISV--QISYRDNDEIQERNSKMGGRPSSNQGSVQHSYNQQSQN 3527 Query: 1357 QS--------YKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQ 1408 QS K+ + I ++NE++ +K+ + N + L++ + Sbjct: 3528 QSSVPNVDKNIKEQYDHQIQSLNEQHRSIKRK--YDNLLIENEDLKRNLSSFYSLQVNNP 3585 Query: 1409 LELKDSEIY-QKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMH 1467 L + + Q+ + + L Q +E E+ + Y+++I L +K EL +LK Sbjct: 3586 LNPAEINLMRQEMDQQKMQLDQLKEEIEDHEENEERYQQQIGQLK-KKIFELE-KQLKES 3643 Query: 1468 ENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALE 1527 + Y+ + K+S KL + N K E + + + L L + + + + L Sbjct: 3644 VAGHQYQAV-KDSFQNFFKLHFDKNSKTNEFIKAEEYLKILLNLL--NIGEQQKKECVLV 3700 Query: 1528 NQEI 1531 Q++ Sbjct: 3701 YQQV 3704 Score = 114 bits (274), Expect = 2e-23 Identities = 219/1161 (18%), Positives = 490/1161 (42%), Gaps = 101/1161 (8%) Query: 455 EHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNV-----KDLIEKLKSAE 509 +HQQ PS T+ E + + ++ E+ + +++K++ V + I++LKS + Sbjct: 215 KHQQQRIAPSQ-EQQTSLEVMKQEHELLEKKYSKKQNQVKELIVLVTQKEKEIKQLKSQQ 273 Query: 510 EQITQLNDEIDAANKNMIKVKSNHKLK--LKQMQKTIDNFSKVSDS----NKEIVRLTEE 563 + I Q +++ + N K NH + QK D + +++ R + E Sbjct: 274 QSIQQNKNQLISGNDE--KQNQNHAFGNCVLNDQKLFDYCLFLEGQYRRLERKVKRKSRE 331 Query: 564 LHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYK---KMIEMENLAETR-LKAISL- 618 + L ++V +K + ++ + ++ E D YK + N++ ++ L +S Sbjct: 332 IEILRKEVKPAVYQKIHQEIQNMKFEE---CEED-YKWNIPTLSQNNISSSKELYTLSKQ 387 Query: 619 LESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKEL 678 + ++ + +EL ++ +++ +K +I + ++ K + QI KKE+ Sbjct: 388 MMQEQSENFKELRKKLKEQEKIINKEQEIIVKEMERNLKNSKDEQKKYQIQ-YENKKKEI 446 Query: 679 ALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNY-IQENMDLTDKLE-KMSAEKISELL 736 + ++L + L + L+++ + ++QN I +L + E K+ E L Sbjct: 447 IQIKQSLTIQINTLSQQVDSLKSENSLLKQEIQNININRQAELNEFEEVKLQLENAEHQL 506 Query: 737 AKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLE 796 +I E Q+KI+ ++ E+ +S+ +I RL + A + + + Sbjct: 507 FQIQREYQTKIE-------EVSEKKYENSQNHITVSQLNDQINRLNQENANLLKEKEQVL 559 Query: 797 RKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQ 856 RK++ ++E Q S+ + E + +L + ++ +K+ EI + +E+ + Q Sbjct: 560 RKSESDKMRIEEFQLKLSK--VNEVQEQYQLEIRQLSVKLADKEN-EIYEKMQEIDQLRQ 616 Query: 857 ILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQT 916 I + +L+I +++ L+++ N+ A+ + Q+ D L++ + + Sbjct: 617 I---SSNDLEIQ--QLKEENQNLIDQINQLHEAQQTLAIHNVQINDELRRLQQQSSVNVQ 671 Query: 917 LIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNM 976 I+ +K +I+ E T I I +K ++ +YE+ + Q +A++ + +ENL Sbjct: 672 QIIIEKTQIQ----ERYTYILKEIEEKNIIIHQYEEKED---QYQAEVMNFTKQLENLQE 724 Query: 977 NVEELNKMNLELIDKH----VQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALN-QK 1031 + +N+ +L+++ +Q Q Q+ EQ IN+ L+ + K K ++I N +K Sbjct: 725 KYDRMNEEFDDLLNEKEQFLIQIQDLQNKCQHEQEINQ-KYLDQIGKYKQDDIDQQNREK 783 Query: 1032 INNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQ 1091 ++ + D SK ++ N E + S Q + K E QIL Q+ Q Sbjct: 784 KYLKEIQKLKDDIDQLSKQSKKNQHENNEEIKAMLTSLQTKNEKLEQENAQILQSSQEQQ 843 Query: 1092 IKELKETKLTFEMNIPKTEGM-IISSTIEPMSDDANNVDXXXXXXXXXXXX-LKVQEEEE 1149 + L ++ + NI + I+ + ++ L + EEE Sbjct: 844 NQLLTNLEMLTQQNIDVQNNLAILEEEVNQKDLKIQQLEQELQLSAQKIETFLSLAEEEN 903 Query: 1150 FI---QERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQL 1206 I Q +++L++Q KL + + KI + LN ++ N+E +L+ E Sbjct: 904 KIKHAQNQALLKQQEQKLEIIIDDLKNKI---DKLNQQIKDQQYENKEVKFELEKCRESK 960 Query: 1207 NTENDNLLSTV---AELRSSISSAVDQRGFEIAELWKQHLAQREADF---QKTEHELRVQ 1260 + + L EL+ I+ +I++L +Q ++Q E QK E +L+ + Sbjct: 961 KEQEEKLQKQKDKNKELKQKITEIEALSVKQISQL-QQQISQYEIQIKNSQKVEQDLKDK 1019 Query: 1261 LSAFESKYEQ----LLDSVQSSTQEETNKIVT-----------MEQVTSLQNKLQDKEEH 1305 ++ + K Q L + S+ ++K V Q+ L+N L DKE Sbjct: 1020 ITEIKEKLSQNQLELSKQKEKSSSSSSSKNVLRSEYIQEIEKYQNQIKELKNNLDDKERE 1079 Query: 1306 LRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQ 1365 R + +Y + N+I ++E + + T +Q +++Q++ Sbjct: 1080 TRKILTEYNEARNKILSYQTEQLENEEKIDKLKEELKVKSNKLNQQQETIDQLQQEIQKK 1139 Query: 1366 SILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTI 1425 + ++ N L S +N+ + + + S++ Q+ ++ Sbjct: 1140 QNIIMSGSN-NLNNSQISQINGNSNQRRSLNNIIVDESGINNTNHV--SQLNQQINDLQN 1196 Query: 1426 TLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERV 1485 L +R EN+ L E K+I+D + ++ E K+++ N Y+ ++ + + ER Sbjct: 1197 LLQER----ENIINNLKEENKQIQDFYHSEQQE------KVNQLENQYQQIENQIK-ERD 1245 Query: 1486 KLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQN 1545 I + ++ + +K++ +LN +++ + +++ + + L+D+ L Sbjct: 1246 DKIAYQSSQLDQK---SKEIQQLNDRIKQITSTKDQITQQYSKLQENNLKLHDQNVELTA 1302 Query: 1546 MVRASSSKIQKHVSFASDTKQ 1566 + + QK + + +Q Sbjct: 1303 KLENFQQEFQKIIVKVKEQEQ 1323 Score = 101 bits (243), Expect = 1e-19 Identities = 250/1366 (18%), Positives = 576/1366 (42%), Gaps = 130/1366 (9%) Query: 143 DVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXX 202 D+ L+ ++ LQ++++ ++ T +L+E++NE + +K+ Sbjct: 2165 DIEKLNENVRNSKKNSQDLQLQLQSLQQTRHNLEEQLNE---LRTLNSKSANQQSQQFSQ 2221 Query: 203 XXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLK-DIESKDVRISSLEEANKLLE 261 ++ +Q+ + ++ E+E +++ K + + KD + E N L+E Sbjct: 2222 LQDEYSELQQNLQQKNLQFKQMLNEHESEKSQLNEKITKIEKQLKDNQTICQEHQN-LIE 2280 Query: 262 AARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQ--SIEPSCEE-KTEIEEKGSLEI 318 +I + K+ + Q K+ +++ E+ K IE Sbjct: 2281 QNNLKIKEQQQKIKEYENQISQMQQQNEEQAKIQQKEQNNLDKEIEKLKKHIESNQKEAA 2340 Query: 319 ANMTELTKK----IELLE-----HLNCQIRQTNKELENKLATMGTESKAVSSPSKKGS-- 367 EL KK I+ ++ HL Q+ Q ++ E ++ + + K + + S Sbjct: 2341 EQQQELIKKHQQEIDNIQNQNDIHLQQQLNQLKQQYEVQIQQITKQQKEEAQKHNQSSEQ 2400 Query: 368 --PLISRKSGRNTASKMKSPWSQLSS-ETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDK 424 I+ K ++ + ++ +++ N+ +K + N+I K+ + Q + + Sbjct: 2401 QIQQITAKYQQDIQNIVQQNEQKIAELNEANKQLSQKDSDNQI-KIHQLQQESENNSTNF 2459 Query: 425 EYVISEK----DTXXXXXXXXXXGKDTLIAQ---LQLEHQQHMEGPSLIHVGTNTEDVNE 477 E ISE + K T I Q +Q+ + + + + + NE Sbjct: 2460 ETKISENSKIYEEKISQISITFETKITEIKQSYEIQINELKQQYETKIQSLQESEKQTNE 2519 Query: 478 IAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKL 537 + + KQEL ++K+ K++ EK ++ +Q+ ++ D +D K + +S K Sbjct: 2520 SSNKE---KQELISKLKEEFQKEIAEKDENHNKQVKEIQDNLD---KQINDYESKIKALQ 2573 Query: 538 KQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESD 597 QK I+ SK +D K I +TE+ +++++L E + D + ++ Sbjct: 2574 VDYQKQIEE-SK-ADHEKNIKEITEK---FEKQISDLNERQQK------DIEGIQINHEF 2622 Query: 598 VYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCS 657 + K E++ ET + + +K D+V + +E E ++ +I Q Q+ Sbjct: 2623 IIK---ELQKKIETLTITLDEINQEKEDIVNKAK------EEAEQEIQNIDQKYRSQI-Q 2672 Query: 658 EIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQEN 717 ++ H + ++ S + + V E +L+ ++L I +D +++ K N I+E Sbjct: 2673 QMHKDHNDYILNTESDQQDAIQTVKEQYELEIQELKQMI---PSDSNELIQKYLNQIKE- 2728 Query: 718 MDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAK-IQERDLYIENIESELSKYKS 776 L +K++++ + + N E Q T ++ K IQ + Y + +E +K Sbjct: 2729 --LEEKIQQLQQQD-----TQSNEENQRLELTIIQLEEKIIQVENKYQIQLSNESESHKQ 2781 Query: 777 RICRLE----ESIAVMEDRRYSLE-RKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLM 831 I +E E IA ++ L + A LG + EKQK + + + +N+ Sbjct: 2782 LIIEIETQNKEKIAELQRIENELRIQIASLLG--MDEKQK------VDQQQKINQQGA-- 2831 Query: 832 DHDRVVEKQLLEIEHENKELQKKNQILLE--ENQNLQISLSDMQQHYNALVEKANRTDLA 889 D+ E+Q++ ++ E ++ Q+ ++ E Q I L + Q Y+ L A R L Sbjct: 2832 --DK--EQQIVILQKEIHTIESTYQLRIQEFEKQIQDIQLRE-SQRYSQL---AQRYLLI 2883 Query: 890 ESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIR-DKKVLNE 948 ES + ++ + S+ T ++Q+ I + + +I++ IE ++++ + +N+ Sbjct: 2884 CLESERLKSSANERNSSSGSNTSQYQSRINELEIQIQN-HIEVISKLQQELNISSTTINQ 2942 Query: 949 KYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYI 1008 + +K Y Q+++ +N ++ + E ++ +++ + + Sbjct: 2943 QIQKIQIYEQQIQSNNFTDQNLLQKYLIVCLEAERLRQVALNQSSKSMAVSNQPVDFDKD 3002 Query: 1009 NEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVS 1068 +I+KL ++Q + ++ L IN+ Q ++S E+++ K+ + ++MQ Sbjct: 3003 QQISKLQIQVQQYEHKMSELLITINSKQ----ELISKLETEINIHIEKVSILNQQMQSQQ 3058 Query: 1069 KQLLDSKQHNEELQILVREQDDQIKELKETK-LTFEMNIPKTEGMIISSTIEPMSDDA-- 1125 Q Q ++ I+ E +++K K T ++ + N +E I+ + + + Sbjct: 3059 TQSSVDTQLLQKYLIVCLEA-ERLKLQKGTSGISIQQNFNDSEIEILKQRVIQLEQEVIY 3117 Query: 1126 -NNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTE 1184 + + K + +E Q+ V+ ++ +L +LQ+ + E +E Sbjct: 3118 KSQIISEFEESKGVKRSTKSSQNQELSQQYLVVCMEAERLQQQLQK---QKADYENQISE 3174 Query: 1185 LTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAV----DQRGFEIAELWK 1240 L D NQE + ++++ LN + + S+ + L+S+ SS V D + EI + Sbjct: 3175 LIKKDKRNQEYLKINDAQIKALNEKLKS--SSQSSLKSNPSSPVNEDQDNKIKEIQAKLE 3232 Query: 1241 QHLAQREADFQKTE--HELRVQLSAFESKYEQLLDSV---QSSTQEETNKIVTMEQVTSL 1295 + Q E+ QK E H ++ + + + ++ + +SS +++ +++ S Sbjct: 3233 KAQMQIESQMQKIEKLHNEKINVEDSNANLNRFINDLKDQKSSIEKQLHQLEKENIEKSH 3292 Query: 1296 Q-NKLQDKEEHLRNLQEKYADVINQIEILR---SEIEDEKVAFXXXXXXXXXXXXXXXXD 1351 Q KL+ ++ L+ E+ + + +++I + E +D+ D Sbjct: 3293 QIEKLEQEKILLQKSVEELGEKLIKMQIQQRDEEEYDDQVFVVNRKMDALKSLVTQLERD 3352 Query: 1352 LRTENQSYKQMQE--QSILNINEE---NAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELT 1406 ++ ++ + MQ S+ +++ + +++ + +++D +A++ +L Sbjct: 3353 VKKYVETSQTMQRIGISLFSVDRDLPLETFVEQLTQNVNDVLKFLEQQIDDKDAQLEDLQ 3412 Query: 1407 HQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLT 1452 L+ KD +IYQ + + + Q+ EF+ + +E I L+ Sbjct: 3413 RNLQAKDDQIYQLQNNHQQSFLQK--EFQTGEDKNMEKVNEILGLS 3456 Score = 54.8 bits (126), Expect = 2e-05 Identities = 79/451 (17%), Positives = 184/451 (40%), Gaps = 31/451 (6%) Query: 1152 QERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTEND 1211 QE +L+++ +K +++E + Q E +L Q+ NQL S ++ +N Sbjct: 236 QEHELLEKKYSKKQNQVKELIVLVTQKEKEIKQLKSQQQSIQQNKNQLISGNDEKQNQNH 295 Query: 1212 NLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFE-SKYEQ 1270 + V DQ+ F+ + + E ++ E+ + + + Y++ Sbjct: 296 AFGNCVLN---------DQKLFDYCLFLEGQYRRLERKVKRKSREIEILRKEVKPAVYQK 346 Query: 1271 LLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDE 1330 + +Q+ EE + T QN + +E ++ + + LR +++++ Sbjct: 347 IHQEIQNMKFEECEEDYKWNIPTLSQNNISSSKELYTLSKQMMQEQSENFKELRKKLKEQ 406 Query: 1331 KVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXX 1390 + + + E + Y+ E N +E Q+K+S Sbjct: 407 EKIINKEQEIIVKEMERNLKNSKDEQKKYQIQYE----NKKKEIIQIKQS---------- 452 Query: 1391 XXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIED 1450 ++N +V L+ ++S + Q+ I +EFE V+ QL E ++ Sbjct: 453 LTIQINTLSQQV----DSLKSENSLLKQEIQNININRQAELNEFEEVKLQLENAEHQLFQ 508 Query: 1451 LTYEKESELAILRLKMHENA-NHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELN 1509 + E ++++ + K +EN+ NH Q +I R+ E N+ + L K ++ Sbjct: 509 IQREYQTKIEEVSEKKYENSQNHITVSQLNDQINRLNQ-ENANLLKEKEQVLRKSESDKM 567 Query: 1510 KALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRD 1569 + +EE K +++ E ++EI L+ ++ + +N + +I + +S+ + + Sbjct: 568 R-IEEFQLKLSKVNEVQEQYQLEIRQLSVKLADKENEIYEKMQEIDQLRQISSNDLEIQQ 626 Query: 1570 EQLDNTMNKELLDAVPRAELDLAMYMLHQRD 1600 + +N + ++ + A+ LA++ + D Sbjct: 627 LKEENQNLIDQINQLHEAQQTLAIHNVQIND 657 >UniRef50_A2EJ43 Cluster: Viral A-type inclusion protein, putative; n=1; Trichomonas vaginalis G3|Rep: Viral A-type inclusion protein, putative - Trichomonas vaginalis G3 Length = 940 Score = 167 bits (407), Expect = 2e-39 Identities = 186/881 (21%), Positives = 408/881 (46%), Gaps = 68/881 (7%) Query: 473 EDVNEIAKVQEQLKQELND--EIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVK 530 + + E K +LK+EL E K+ + +L+ +++ ++QI DEI N+N+ K K Sbjct: 6 KQIEEKDKQINELKEELQKQTEEKETEINELMNQIEDLQKQI----DEIKNQNENLQKEK 61 Query: 531 SNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDS 590 N L +M K ID+ K + ++ L EE +++EL+++ +LQ + Sbjct: 62 EN---SLNEMNKQIDDLQKEKEETEKA--LIEENEDYKNQLSELKKQIEDLQNENEEKVE 116 Query: 591 GRMIESDVYKKMI-EMENLAETRLKAISLLES--QKF--DLVQELHILQQKYDEVEDKLA 645 E++ + I ++++ E K++S E QKF +L Q++ L+QK V D+ Sbjct: 117 NLKKENEEFNNEIKDLQDQIELLKKSMSESEDKDQKFVIELNQQIEKLKQK---VSDE-K 172 Query: 646 DISQLQSDQVCS-EIKSVHLEEQIDALSASKKELALVIENL--KL----DKEQLYGTIKD 698 D+ Q++ +++ + K+ L EQ + L+ K EL IE L KL +KE+L I + Sbjct: 173 DLIQVKDEEIIDLKQKNTDLSEQNNKLNEDKNELEKQIEELAQKLSDESEKEKLKQEINE 232 Query: 699 LENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQ 758 L+++KE N +++ ++ +LT K+ ++ + IS+ +I+ E +K +D + Sbjct: 233 LKSEKE---NSEKDFNKKLENLTQKVTELE-DSISQKTREIDEAETAKEDISLKLDNLAE 288 Query: 759 ERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTI 818 E + +N+ K ++ E+ ED + E S +E K Sbjct: 289 ENEKLSQNLSEIYEKLNEKVTETEKLQKENEDLKSENELLKKDSDSAQEELMKENENLKK 348 Query: 819 QEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNA 878 + E+ ++ L +K + +++ + +E+ +N EE++ Q + D+ Q Sbjct: 349 ENGEITEKIEELQKEIGERQKTVEDLKQKIEEINSQNA---EESEKNQKEIDDLTQEIEE 405 Query: 879 LVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIES 938 + +K + + K + L+ +K+ E+Q I +KE +DL+ N E Sbjct: 406 INQKLDEKQKENDDLKKEKENLQKEVDEIKKNFEENQNQIENLQKENDDLKKGMNQSSEE 465 Query: 939 AIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQT 998 + K++ E+ +KN E + + ++ + E +N ++E K +E I + +++ Q Sbjct: 466 --KQKEI--EEIKKNFE---EKQKEIDDLTQENEEMNQKLDEKQK-EIEEIKQKIEENQK 517 Query: 999 QSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLE 1058 Q+ D ++ + ++ L +QK ++ + +N+ Q + + + +++ + +LE Sbjct: 518 QNVDLKKEVEDLTQEIEKLEEQKSQK----EENVNSEQENLQKQIEELKNEKETISNELE 573 Query: 1059 NMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTI 1118 + + +++ L + + N EL I + E+ Q KE+ + N E + + Sbjct: 574 SKTKHNEKLVSSLQEFAKKNAELDITI-ERLTQEKEVLINNVNDLQNNVDAEIRDLKVKL 632 Query: 1119 EPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQL 1178 + ++ + ++ LK Q++EE +E Q+++ L E+ + +I +L Sbjct: 633 QEKDEEIDGLNEQIEQIIKENNDLK-QKQEENQKENEQKQKENEDLKKEVDDLTQEIEKL 691 Query: 1179 ETLNTELTGHDVVN-----QEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGF 1233 E ++ +V + Q+QI +LK ++EQ +N++L+ E+ D++ Sbjct: 692 EEQKSQKEEENVNSEQENLQKQIEELKKEVEQYKKQNEDLIEENEEM--------DEK-M 742 Query: 1234 EIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKI-VTMEQV 1292 +I + + + + + + + L+ L E + E+++ + +E +++ +E+ Sbjct: 743 KILQKQIEEIKETNEESSEQIYALKKDLEIAEQEKERIVKMEREQNMKEISQLKFEVEEK 802 Query: 1293 TSL----QNKLQDKEEHLRNLQEK-YADVINQIEILRSEIE 1328 + QNK Q E + ++K A+V + + +S I+ Sbjct: 803 RRISEEYQNKCQSIAEEFKQREKKVLAEVEKKFNMFKSAID 843 Score = 145 bits (352), Expect = 8e-33 Identities = 176/834 (21%), Positives = 373/834 (44%), Gaps = 70/834 (8%) Query: 788 MEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHE 847 M + + +E K Q+ +E QK E + +EL+N++ L +KQ+ EI+++ Sbjct: 1 MNEIKKQIEEKDKQINELKEELQKQTEEKETEINELMNQIEDL-------QKQIDEIKNQ 53 Query: 848 NKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNL 907 N+ LQK+ + L E N QI D+Q+ EKA L E E+ Y+ QL +L+ + Sbjct: 54 NENLQKEKENSLNE-MNKQID--DLQKEKEE-TEKA----LIE-ENEDYKNQLSELKKQI 104 Query: 908 KRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEY 967 + + +E++ + KKE E+ E + KK ++E +K+ ++V +L Q+++ Sbjct: 105 EDLQNENEEKVENLKKENEEFNNEIKDLQDQIELLKKSMSESEDKDQKFVIELNQQIEKL 164 Query: 968 KNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQK---DEE 1024 K + + ++ ++ ++L K+ + Q+ E NE+ K L QK + E Sbjct: 165 KQKVSDEKDLIQVKDEEIIDLKQKNTDLSE-QNNKLNEDK-NELEKQIEELAQKLSDESE 222 Query: 1025 IIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQIL 1084 L Q+IN + + D+ KL T K+ +E+ + + ++++ +++ E++ + Sbjct: 223 KEKLKQEINELKSEKENSEKDFNKKLENLTQKVTELEDSISQKTREIDEAETAKEDISLK 282 Query: 1085 VREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKV 1144 + ++ ++L + E+ E + + ++ ++D + + + Sbjct: 283 LDNLAEENEKLSQN--LSEIYEKLNEKVTETEKLQKENEDLKSENELLKKDSDSAQEELM 340 Query: 1145 QEEEEFIQERSVLQEQSAKLNTELQECYTKIIQL----ETLNTELTGHDVVNQEQINQLK 1200 +E E +E + E+ +L E+ E + L E +N++ NQ++I+ L Sbjct: 341 KENENLKKENGEITEKIEELQKEIGERQKTVEDLKQKIEEINSQNAEESEKNQKEIDDLT 400 Query: 1201 SKLEQLNTENDNLLSTVAELRS---SISSAVDQ--RGFEIAELWKQHLAQREADFQK--- 1252 ++E++N + D +L+ ++ VD+ + FE + ++L + D +K Sbjct: 401 QEIEEINQKLDEKQKENDDLKKEKENLQKEVDEIKKNFEENQNQIENLQKENDDLKKGMN 460 Query: 1253 -TEHELRVQLSAFESKYEQLLDSVQSSTQE--ETNKIVTMEQ--VTSLQNKLQDKEEHLR 1307 + E + ++ + +E+ + TQE E N+ + +Q + ++ K+++ ++ Sbjct: 461 QSSEEKQKEIEEIKKNFEEKQKEIDDLTQENEEMNQKLDEKQKEIEEIKQKIEENQKQNV 520 Query: 1308 NLQEKYADVINQIEIL---RSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQE 1364 +L+++ D+ +IE L +S+ E+ + + E +S + E Sbjct: 521 DLKKEVEDLTQEIEKLEEQKSQKEENVNSEQENLQKQIEELKNEKETISNELESKTKHNE 580 Query: 1365 QSILNINE---ENAQLKKSSXXXXXXXXXXXXRVND----AEAKVLELTHQLELKDSEIY 1417 + + ++ E +NA+L + VND +A++ +L +L+ KD EI Sbjct: 581 KLVSSLQEFAKKNAELDITIERLTQEKEVLINNVNDLQNNVDAEIRDLKVKLQEKDEEID 640 Query: 1418 QKTHEYTITLTQRND----------EFENVRQQLVEYEKRIEDLTYEKESELAILRLKMH 1467 + + + ND E E +++ + +K ++DLT E E K Sbjct: 641 GLNEQIEQIIKENNDLKQKQEENQKENEQKQKENEDLKKEVDDLTQEIEKLEEQKSQKEE 700 Query: 1468 ENAN-HYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALE---EEVAKTNE-- 1521 EN N E +QK+ E E K +E+ + + + N+++ E K L+ EE+ +TNE Sbjct: 701 ENVNSEQENLQKQIE-ELKKEVEQYKKQNEDLIEENEEMDEKMKILQKQIEEIKETNEES 759 Query: 1522 -MQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDN 1574 Q +++EI E + M R + K + F + K+ E+ N Sbjct: 760 SEQIYALKKDLEIA--EQEKERIVKMEREQNMKEISQLKFEVEEKRRISEEYQN 811 Score = 145 bits (351), Expect = 1e-32 Identities = 206/968 (21%), Positives = 435/968 (44%), Gaps = 98/968 (10%) Query: 151 IKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXX 210 I E N + LQ ++ ++ +LQ+ EK+ + NK Sbjct: 33 INELMNQIEDLQKQIDEIKNQNENLQK---EKENSLNEMNKQIDDLQKEKEETEKALIEE 89 Query: 211 XEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLE 270 ED K Q++++++ ++ E +++ + L K+ E + I L++ +LL+ + E + Sbjct: 90 NEDYKNQLSELKKQIEDLQNENEEKVENLKKENEEFNNEIKDLQDQIELLKKSMSESEDK 149 Query: 271 HSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEK---TEIEEKGSLEIANMTELTKK 327 K EL Q L + E + K T++ E+ + + EL K+ Sbjct: 150 DQKFVIELNQQIEKLKQKVSDEKDLIQVKDEEIIDLKQKNTDLSEQNNKLNEDKNELEKQ 209 Query: 328 IELL----------EHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRN 377 IE L E L +I + E EN + + ++ + IS+K+ Sbjct: 210 IEELAQKLSDESEKEKLKQEINELKSEKENSEKDFNKKLENLTQKVTELEDSISQKTREI 269 Query: 378 TASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXX 437 ++ L + L ++ +K +++N L + + LN+ + + E + E + Sbjct: 270 DEAETAKEDISLKLDNLAEENEK-LSQN----LSEIYEKLNEKVTETEKLQKENEDLKSE 324 Query: 438 XXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAK-VQEQLK--QELNDEIK 494 D+ +L E++ + G TE + E+ K + E+ K ++L +I+ Sbjct: 325 NELLKKDSDSAQEELMKENENLKK-----ENGEITEKIEELQKEIGERQKTVEDLKQKIE 379 Query: 495 DVNVKDLIEKLKSAEEQITQLNDEIDAANKNMI-KVKSNHKLKLKQ--MQKTIDNFSKVS 551 ++N ++ E K+ +E I L EI+ N+ + K K N LK ++ +QK +D K Sbjct: 380 EINSQNAEESEKNQKE-IDDLTQEIEEINQKLDEKQKENDDLKKEKENLQKEVDEIKKNF 438 Query: 552 DSNK-EIVRLTEELHHLSQKVAELEEEKGN-LQLHLVDYDSGRMIESDVYKKMIEMENLA 609 + N+ +I L +E L + + + EEK ++ +++ + D+ ++ EM Sbjct: 439 EENQNQIENLQKENDDLKKGMNQSSEEKQKEIEEIKKNFEEKQKEIDDLTQENEEMNQKL 498 Query: 610 ETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQID 669 + + K I ++ QK + Q+ ++ +K EVED +I +L+ E KS EE ++ Sbjct: 499 DEKQKEIEEIK-QKIEENQKQNVDLKK--EVEDLTQEIEKLE------EQKS-QKEENVN 548 Query: 670 ALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSA 729 + ++ L IE LK +KE + ++ E +++ LQ + ++N +L +E+++ Sbjct: 549 S---EQENLQKQIEELKNEKETISNELESKTKHNEKLVSSLQEFAKKNAELDITIERLTQ 605 Query: 730 EKISELLAKINHEEQSKIQTQF-GIDAKIQERDLYI----ENIESELSKYKSRICRLEES 784 EK E+L ++ Q+ + + + K+QE+D I E IE + + + EE+ Sbjct: 606 EK--EVLINNVNDLQNNVDAEIRDLKVKLQEKDEEIDGLNEQIEQIIKENNDLKQKQEEN 663 Query: 785 IAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEI 844 E ++ E ++ QE +K + + +E+E VN ++KQ+ E+ Sbjct: 664 QKENEQKQKENEDLKKEVDDLTQEIEKLEEQKSQKEEENVN------SEQENLQKQIEEL 717 Query: 845 EHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLE 904 + E ++ +K+N+ L+EEN+ + + +Q+ +E+ T+ E S + +DLE Sbjct: 718 KKEVEQYKKQNEDLIEENEEMDEKMKILQKQ----IEEIKETN--EESSEQIYALKKDLE 771 Query: 905 SNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQL 964 I + + IV+ ++E EI +Q++ + +K+ ++E+Y+ + + + Sbjct: 772 -----IAEQEKERIVKMEREQNMKEI---SQLKFEVEEKRRISEEYQNKCQSIAE----- 818 Query: 965 QEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEE 1024 E+K + + VE+ M IDK V K Q N++N + A+ K E Sbjct: 819 -EFKQREKKVLAEVEKKFNMFKSAIDKIVSKLQIVD--------NKLNNIKAIEKTVIES 869 Query: 1025 IIALNQKINNAQVSY-MSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQI 1083 + + I++ ++++ +S ++ K + ++ E+ Q +KQ++ + +Q Sbjct: 870 LAPV-LGIDSTEINFDVSSITPLVEKAKRHISREARWREKYQN-AKQIIYA------IQT 921 Query: 1084 LVREQDDQ 1091 +++ +D Q Sbjct: 922 IIKSEDPQ 929 Score = 141 bits (341), Expect = 2e-31 Identities = 179/891 (20%), Positives = 397/891 (44%), Gaps = 56/891 (6%) Query: 675 KKELALVIENLKLDKEQLYGTIKDLENDKEDIMNK---LQNYIQENMDLTDKLEKMSAEK 731 KK++ + + KE+L ++ E + ++MN+ LQ I E + + L+K Sbjct: 5 KKQIEEKDKQINELKEELQKQTEEKETEINELMNQIEDLQKQIDEIKNQNENLQKEKENS 64 Query: 732 ISELLAKINHEEQSKIQTQFGI-----DAKIQERDL--YIENIESE-LSKYKSRICRLEE 783 ++E+ +I+ ++ K +T+ + D K Q +L IE++++E K ++ EE Sbjct: 65 LNEMNKQIDDLQKEKEETEKALIEENEDYKNQLSELKKQIEDLQNENEEKVENLKKENEE 124 Query: 784 SIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLE 843 ++D + +E + + QK E Q ++L +++ D +V ++++++ Sbjct: 125 FNNEIKDLQDQIELLKKSMSESEDKDQKFVIELNQQIEKLKQKVSDEKDLIQVKDEEIID 184 Query: 844 IEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKAN-RTDLAESESTKYQTQLRD 902 ++ +N +L ++N L E+ L+ + ++ Q + EK + ++ E +S K ++ +D Sbjct: 185 LKQKNTDLSEQNNKLNEDKNELEKQIEELAQKLSDESEKEKLKQEINELKSEKENSE-KD 243 Query: 903 LESNLKRITH---EHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQ 959 L+ +T E + I QK +EI++ E T E L E+ EK + +++ Sbjct: 244 FNKKLENLTQKVTELEDSISQKTREIDEAE----TAKEDISLKLDNLAEENEKLSQNLSE 299 Query: 960 LEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLK 1019 + +L E E L E+L N EL+ K Q + E E ++ ++ Sbjct: 300 IYEKLNEKVTETEKLQKENEDLKSEN-ELLKKDSDSAQEELMKENENLKKENGEITEKIE 358 Query: 1020 QKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNE 1079 + +EI + + + + + S + + +++++ +E++ ++++L + ++ N+ Sbjct: 359 ELQKEIGERQKTVEDLKQKIEEINSQNAEESEKNQKEIDDLTQEIEEINQKLDEKQKEND 418 Query: 1080 ELQILVREQDDQIKELKETKLTFEMNIPKTEGM-IISSTIEPMSDDANNVDXXXXXXXXX 1138 +L+ +E+++ KE+ E K FE N + E + + ++ + ++ Sbjct: 419 DLK---KEKENLQKEVDEIKKNFEENQNQIENLQKENDDLKKGMNQSSEEKQKEIEEIKK 475 Query: 1139 XXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTG--HDVVNQ-EQ 1195 K +E ++ QE + ++ + E++E KI + + N +L D+ + E+ Sbjct: 476 NFEEKQKEIDDLTQENEEMNQKLDEKQKEIEEIKQKIEENQKQNVDLKKEVEDLTQEIEK 535 Query: 1196 INQLKS-KLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTE 1254 + + KS K E +N+E +NL + EL++ + ++ E + L +F K Sbjct: 536 LEEQKSQKEENVNSEQENLQKQIEELKNEKETISNE--LESKTKHNEKLVSSLQEFAKKN 593 Query: 1255 HELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYA 1314 EL + + + E L+++V + Q + ++ L+ KLQ+K+E + L E+ Sbjct: 594 AELDITIERLTQEKEVLINNV-NDLQNNVD-----AEIRDLKVKLQEKDEEIDGLNEQIE 647 Query: 1315 DVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQ-SILNINEE 1373 +I + L+ + ++E DL E + ++ + Q N+N E Sbjct: 648 QIIKENNDLKQK-QEENQKENEQKQKENEDLKKEVDDLTQEIEKLEEQKSQKEEENVNSE 706 Query: 1374 NAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDE 1433 L+K + D ++E +++ K +I QK E + + N+E Sbjct: 707 QENLQKQIEELKKEVEQYKKQNED----LIEENEEMDEK-MKILQKQIE---EIKETNEE 758 Query: 1434 FENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNV 1493 +Q+ +K +E EKE +KM N E Q + E+E + I E Sbjct: 759 SS---EQIYALKKDLEIAEQEKER-----IVKMEREQNMKEISQLKFEVEEKRRISEEYQ 810 Query: 1494 KITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQ 1544 +S++ + E K L E K N ++A++ ++ +++++ N++ Sbjct: 811 NKCQSIAEEFKQRE-KKVLAEVEKKFNMFKSAIDKIVSKLQIVDNKLNNIK 860 Score = 123 bits (297), Expect = 4e-26 Identities = 141/674 (20%), Positives = 302/674 (44%), Gaps = 43/674 (6%) Query: 922 KKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVE-E 980 KK+IE+ + + N E + + + + + + L+ Q+ E KN ENL E Sbjct: 5 KKQIEEKDKQINELKEELQKQTEEKETEINELMNQIEDLQKQIDEIKNQNENLQKEKENS 64 Query: 981 LNKMNLELIDKHVQKQQTQSP--DYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVS 1038 LN+MN ++ D +K++T+ + E Y N++++L ++ E +K+ N + Sbjct: 65 LNEMNKQIDDLQKEKEETEKALIEENEDYKNQLSELKKQIEDLQNE---NEEKVENLKKE 121 Query: 1039 YMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKET 1098 ++ + Q ++M E + K +++ Q E+L+ V ++ D I ++K+ Sbjct: 122 NEEFNNEIKDLQDQIELLKKSMSESEDKDQKFVIELNQQIEKLKQKVSDEKDLI-QVKDE 180 Query: 1099 KLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQ 1158 ++ ++ T+ +S +++D N ++ L + E+E +++ + + Sbjct: 181 EI-IDLKQKNTD---LSEQNNKLNEDKNELE---KQIEELAQKLSDESEKEKLKQ-EINE 232 Query: 1159 EQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVA 1218 +S K N+E ++ K+ L TEL +I++ ++ E ++ + DNL Sbjct: 233 LKSEKENSE-KDFNKKLENLTQKVTELEDSISQKTREIDEAETAKEDISLKLDNLAEENE 291 Query: 1219 ELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSS 1278 +L ++S ++ ++ E K Q+E + K+E+EL + S +S E+L+ + Sbjct: 292 KLSQNLSEIYEKLNEKVTETEK---LQKENEDLKSENELLKKDS--DSAQEELMKE-NEN 345 Query: 1279 TQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQ--IEILRSEIE-DEKVAFX 1335 ++E +I E++ LQ ++ ++++ + +L++K ++ +Q E +++ E D+ Sbjct: 346 LKKENGEIT--EKIEELQKEIGERQKTVEDLKQKIEEINSQNAEESEKNQKEIDDLTQEI 403 Query: 1336 XXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRV 1395 DL+ E ++ ++ ++ N E Q++ Sbjct: 404 EEINQKLDEKQKENDDLKKEKENLQKEVDEIKKNFEENQNQIENLQKENDDLKKGMNQSS 463 Query: 1396 NDAEAKVLELTHQLELKDSEI---YQKTHEYTITLTQRNDEFENVRQQL-------VEYE 1445 + + ++ E+ E K EI Q+ E L ++ E E ++Q++ V+ + Sbjct: 464 EEKQKEIEEIKKNFEEKQKEIDDLTQENEEMNQKLDEKQKEIEEIKQKIEENQKQNVDLK 523 Query: 1446 KRIEDLTYEKESELAILRLKMHENAN-HYETMQKESEIERVKLIEELNVKITESVSLNKQ 1504 K +EDLT E E +L + + EN N E +QK +IE +K E E S K Sbjct: 524 KEVEDLTQEIE-KLEEQKSQKEENVNSEQENLQK--QIEELK--NEKETISNELESKTKH 578 Query: 1505 VAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDT 1564 +L +L+E K E+ +E E L + + +LQN V A ++ + + Sbjct: 579 NEKLVSSLQEFAKKNAELDITIERLTQEKEVLINNVNDLQNNVDAEIRDLKVKLQEKDEE 638 Query: 1565 KQGRDEQLDNTMNK 1578 G +EQ++ + + Sbjct: 639 IDGLNEQIEQIIKE 652 Score = 114 bits (274), Expect = 2e-23 Identities = 127/592 (21%), Positives = 261/592 (44%), Gaps = 53/592 (8%) Query: 1014 LNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLD 1073 +N + KQ +E+ +++IN + + E+++ + ++E++++++ + Q + Sbjct: 1 MNEIKKQIEEK----DKQINELKEELQKQTEEKETEINELMNQIEDLQKQIDEIKNQNEN 56 Query: 1074 -SKQHNEELQILVREQDDQIKELKET-KLTFEMNIP-KTEGMIISSTIEPM-SDDANNVD 1129 K+ L + ++ DD KE +ET K E N K + + IE + +++ V+ Sbjct: 57 LQKEKENSLNEMNKQIDDLQKEKEETEKALIEENEDYKNQLSELKKQIEDLQNENEEKVE 116 Query: 1130 XXXXXXXXXXXXLK-VQEEEEFIQER-SVLQEQSAKLNTELQECYTKIIQLETLNTELTG 1187 +K +Q++ E +++ S +++ K EL + K+ Q + +L Sbjct: 117 NLKKENEEFNNEIKDLQDQIELLKKSMSESEDKDQKFVIELNQQIEKLKQKVSDEKDLIQ 176 Query: 1188 HDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIA-ELWKQHLAQR 1246 V E+I LK K L+ +N+ L EL I + E E KQ + + Sbjct: 177 ---VKDEEIIDLKQKNTDLSEQNNKLNEDKNELEKQIEELAQKLSDESEKEKLKQEINEL 233 Query: 1247 EADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVT-SLQNKLQDKEEH 1305 +++ + +E + +L K +L DS+ T+E E ++ L N ++ E+ Sbjct: 234 KSEKENSEKDFNKKLENLTQKVTELEDSISQKTREIDEAETAKEDISLKLDNLAEENEKL 293 Query: 1306 LRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQ 1365 +NL E Y + ++ E EK+ DL++EN+ K+ + Sbjct: 294 SQNLSEIYEKLNEKVT------ETEKLQ-------------KENEDLKSENELLKKDSDS 334 Query: 1366 SILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTI 1425 + + +EN LKK + + + + V +L ++E +S+ +++ + Sbjct: 335 AQEELMKENENLKKENGEITEKIEELQKEIGERQKTVEDLKQKIEEINSQNAEESEKNQK 394 Query: 1426 TLTQRNDEFENVRQQLVEYEKRIEDLTYEKES---ELAILRLKMHENANHYETMQKE--- 1479 + E E + Q+L E +K +DL EKE+ E+ ++ EN N E +QKE Sbjct: 395 EIDDLTQEIEEINQKLDEKQKENDDLKKEKENLQKEVDEIKKNFEENQNQIENLQKENDD 454 Query: 1480 -------SEIERVKLIEELNVKITESV----SLNKQVAELNKALEEEVAKTNEMQTALEN 1528 S E+ K IEE+ E L ++ E+N+ L+E+ + E++ +E Sbjct: 455 LKKGMNQSSEEKQKEIEEIKKNFEEKQKEIDDLTQENEEMNQKLDEKQKEIEEIKQKIEE 514 Query: 1529 QEIEIVTLNDEITNL-QNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKE 1579 + + V L E+ +L Q + + K QK + S+ ++ +Q++ N++ Sbjct: 515 NQKQNVDLKKEVEDLTQEIEKLEEQKSQKEENVNSE-QENLQKQIEELKNEK 565 Score = 46.8 bits (106), Expect = 0.005 Identities = 83/425 (19%), Positives = 170/425 (40%), Gaps = 26/425 (6%) Query: 143 DVTHLSNTIKEKDNALSVLQVK----MKIMETTILDLQEKINEKDQIIEAKNKAT---TX 195 +V + +E N + LQ + K M + + Q++I E + E K K T Sbjct: 430 EVDEIKKNFEENQNQIENLQKENDDLKKGMNQSSEEKQKEIEEIKKNFEEKQKEIDDLTQ 489 Query: 196 XXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEE 255 E+ KQ++ + Q+ + ++ E +D Q + K E K + ++ Sbjct: 490 ENEEMNQKLDEKQKEIEEIKQKIEENQKQNVDLKKEVEDLTQEIEKLEEQKSQKEENVNS 549 Query: 256 ANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGS 315 + L+ E+ E ++ ELE AK++ E + +EK Sbjct: 550 EQENLQKQIEELKNEKETISNELESKTKHNEKLVSSLQEFAKKNAELDITIERLTQEKEV 609 Query: 316 LEIANMTELTKKIEL-LEHLNCQIRQTNKE---LENKLATMGTESKAVSSPSKKGSPLIS 371 L I N+ +L ++ + L ++++ ++E L ++ + E+ + ++ Sbjct: 610 L-INNVNDLQNNVDAEIRDLKVKLQEKDEEIDGLNEQIEQIIKENNDLKQKQEENQKENE 668 Query: 372 RKSGRNTASKMKSPWSQLSSETLNQDTDKKINKN---EIAKLEMVIQSLNKDLVDKEYVI 428 +K N K + E L + +K +N E L+ I+ L K++ ++Y Sbjct: 669 QKQKENEDLKKEVDDLTQEIEKLEEQKSQKEEENVNSEQENLQKQIEELKKEV--EQYKK 726 Query: 429 SEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQE 488 +D K I Q Q+E + S + +D+ EIA EQ K+ Sbjct: 727 QNEDLIEENEEMDEKMK---ILQKQIEEIKETNEESSEQIYALKKDL-EIA---EQEKER 779 Query: 489 LNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMI-KVKSNHKLKLKQMQKTIDNF 547 + ++ N+K+ I +LK E+ ++++E +++ + K K L +++K + F Sbjct: 780 IVKMEREQNMKE-ISQLKFEVEEKRRISEEYQNKCQSIAEEFKQREKKVLAEVEKKFNMF 838 Query: 548 SKVSD 552 D Sbjct: 839 KSAID 843 >UniRef50_A0DJQ4 Cluster: Chromosome undetermined scaffold_53, whole genome shotgun sequence; n=2; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_53, whole genome shotgun sequence - Paramecium tetraurelia Length = 1565 Score = 166 bits (404), Expect = 4e-39 Identities = 261/1137 (22%), Positives = 497/1137 (43%), Gaps = 109/1137 (9%) Query: 473 EDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKV--K 530 ED N+ K+++Q+ Q LND + K L +L+ + Q+ Q+ D+ D NK ++K + Sbjct: 291 EDENK--KLRDQINQILND-LDQWRKKALTLELQVFDLQV-QVTDQ-DNNNKLLVKEIER 345 Query: 531 SNHKLKLKQ--MQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDY 588 N +L KQ +++ N + D KE+ L +++ + + EL+ + D Sbjct: 346 LNQQLASKQQEIERLKTNLQQAEDHIKELQGLKQQIQEKQRVIDELKRKN--------DE 397 Query: 589 DSGRMIESDVYKKMIEMENLAETRL-KAISLLESQKFDLVQELHILQQKYDEVEDKLADI 647 + +++E++ KK +E T L K +L Q L + L QQ YD++ +KL + Sbjct: 398 QAKQLLENEKLKKQLEQIRGYNTDLQKQNGVLNYQIDQLNRTLENKQQAYDKLNNKLKFV 457 Query: 648 SQLQSD--QVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKED 705 + Q EI + +E+Q LS EL+ + + LKL EQL K+L+N +E Sbjct: 458 ENDNNTLRQQVLEINELQIEKQ-SLLS----ELSSLDKELKLKSEQLANVEKELQNLQEK 512 Query: 706 IMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIE 765 + I+ ++ M I+EL +I + + + I + Y++ Sbjct: 513 LQQL--RIIELELNRAKSQIDMKDRDIAELRKQIKDLTVKNFELEQRLKELISKETEYLK 570 Query: 766 NIESELSKYKSRICRLEESIAVMEDRRYSLERKAD---QLGSYLQEKQKAYSEYTIQEDE 822 I + YKS +L +A +E L+ + D +L S L+ Q+ Y + + Sbjct: 571 -IFQQCETYKSLNDQLNLQLAQLEAENQQLQSQVDGLAELQSQLKVLQQKYEQTLKINSD 629 Query: 823 LVNRLAVLMDHDRVVEKQL----LEIEHENKELQKKNQILLEENQ---NLQISLSDMQQH 875 L +R L + +++Q L N ELQ+ N +L +++Q +L++ L+ +Q Sbjct: 630 LSSRNQQLQQQLQNIQQQKNVNNLRDNQINIELQRNNTLLNQKSQQIEDLRLKLAKAEQQ 689 Query: 876 Y----NALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIE 931 N L K D + K Q ++++LES L + Q+L Q D ++ Sbjct: 690 IDTLNNQLQNKQQELDNQIVLNAKLQDRIKELESELLNLKKTLQSLQDQNTSLKNDHHLQ 749 Query: 932 FNTQIESAIRDKKVLN----------EKYEKNIEYVTQL---EAQLQEY---KNNIENLN 975 E +R ++ + EKY +N + L E +L + KN + +LN Sbjct: 750 LQELREEILRKQEEIKALQKLADQYKEKYLENDRQLADLKGLERKLNDITIQKNQLADLN 809 Query: 976 MNVEE-LNKMNLELIDKHVQKQQTQS-PDYTEQYINEINKLNALLKQKDEEIIALNQKIN 1033 ++ ++K+ E ++ Q+T D +QY I KL A K++EI LN K+ Sbjct: 810 TAYQDQISKLQSENRSLQIKIQETHLFEDQNKQYEAIIEKLKAENTLKNKEITELNIKLP 869 Query: 1034 NAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIK 1093 +YM VSD E KL + + + + E++R+ ++ + + EEL+ + + ++ Sbjct: 870 ----TYMQQVSDLEKKLLRTDQQFQIYKNEVERLRQEKQNLIKEIEELKRKNKNLEQKVN 925 Query: 1094 ELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQE 1153 EL + E+ IP+ E + + N VD + +Q E+ Sbjct: 926 ELNHLQ---EL-IPQLE--------QKANRLQNQVDKLSKQNLDYNDQINLQNEQ----- 968 Query: 1154 RSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNL 1213 L +Q ++ T L + + + QLE+ N L + N +++ K + LN E + Sbjct: 969 ---LSQQELQIRT-LFQVKSNLQQLES-NYSLVVQQL-NDQRLQSAKLEQAFLN-EQEQH 1021 Query: 1214 LSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKT---EHELRVQLSAFESKYEQ 1270 T EL+ + + +DQ +I +L K ++ + E K E EL+ + F + Sbjct: 1022 QKTADELKKA-TKELDQLKNKIEQLEK-YIKELEGKLIKDRILEQELKEAIG-FNLTLDT 1078 Query: 1271 LLDSVQSSTQEETNKIVTM-EQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIED 1329 L+ V+ + N+I + E++ + K K+ ++ LQ A+ I Q+ I+ E+ D Sbjct: 1079 KLNQVRQENESLKNEITQLKEELEQWKAKYLQKDNEVKTLQVYKAEAI-QMRIINDELTD 1137 Query: 1330 EKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQM---QEQSILNINEENAQ---LKKSSXX 1383 DL+ + KQ EQ + I Q L++ Sbjct: 1138 NFNKLTKQLKAITLEKQIMEEDLQQQIADQKQRIAELEQLVAQIEPLQTQVNDLQQLVNK 1197 Query: 1384 XXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHE-YTITLTQRNDEFENVRQQLV 1442 ++ +A+ KV EL ++E E+ +K ++ ++ + ++ L Sbjct: 1198 LQNENKLLAKKLGEAQTKVKELESKIEAY--EVMEKDYQKLQANYAEKAQDLRMTKEDLD 1255 Query: 1443 EYEKRIEDLTYEKES---ELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESV 1499 + +++ +T EKE+ +A+L ++ E H ++E E +L+ + + Sbjct: 1256 KTTLQLDKVTKEKENLDMRIAMLAAEI-ERQKHLNKNKQEKIDELTNQNTDLSNVVAQLE 1314 Query: 1500 SLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQK 1556 L+ + L++ ++E KT++ Q L ++ EI LN+E+ LQN V +I++ Sbjct: 1315 PLDPENTRLSEQIQEMKKKTDQDQLDLMKKDDEINKLNNEVYGLQNKVALLGPEIER 1371 Score = 161 bits (392), Expect = 1e-37 Identities = 259/1257 (20%), Positives = 538/1257 (42%), Gaps = 96/1257 (7%) Query: 370 ISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVIS 429 + + R A ++ S S L T + K+ +E KL +I+ L + K+ I+ Sbjct: 116 VEQWKARFFALQITSGGSGLEELTGMYEMRLKLLSDENGKLLALIKQLINENEQKDLAIA 175 Query: 430 EKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQEL 489 ++D D L L+ + +++E + E++ A+ QE EL Sbjct: 176 QRDNKIYQLELNQHEHDALQELLKKKQDENLELRGKLQ---GLEELLIDARKQEIENFEL 232 Query: 490 NDEIKDVNVKDLI--EKLKSAEEQITQLNDEIDAA--NKNMIKVKSNHKLKLKQMQKTID 545 +IK++ + + +K K +EE +L E+ N + + S + +L M D Sbjct: 233 QSKIKNLENELAMWKDKFKLSEEDRNRLLQELRELLERMNQLNLDSVKRGQLSTMDLLED 292 Query: 546 NFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEM 605 K+ D +I ++ +L +K LE + +LQ+ + D D+ + +++ + Sbjct: 293 ENKKLRD---QINQILNDLDQWRKKALTLELQVFDLQVQVTDQDNNNKLLVKEIERLNQQ 349 Query: 606 ENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLE 665 + ++ + Q D ++EL L+Q+ E + + ++ + +Q +++ L+ Sbjct: 350 LASKQQEIERLKTNLQQAEDHIKELQGLKQQIQEKQRVIDELKRKNDEQAKQLLENEKLK 409 Query: 666 EQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTD--- 722 +Q++ + +L L +QL T+++ + + + NKL+ +N L Sbjct: 410 KQLEQIRGYNTDLQKQNGVLNYQIDQLNRTLENKQQAYDKLNNKLKFVENDNNTLRQQVL 469 Query: 723 KLEKMSAEKISEL--LAKINHEEQSKIQTQFGIDAK---IQERDLYIENIESELSKYKSR 777 ++ ++ EK S L L+ ++ E + K + ++ + +QE+ + IE EL++ KS+ Sbjct: 470 EINELQIEKQSLLSELSSLDKELKLKSEQLANVEKELQNLQEKLQQLRIIELELNRAKSQ 529 Query: 778 ICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVV 837 I + IA + + L K +L L+E +EY ++ + + + Sbjct: 530 IDMKDRDIAELRKQIKDLTVKNFELEQRLKELISKETEYL----KIFQQCETYKSLNDQL 585 Query: 838 EKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQ 897 QL ++E EN++LQ + L E L++ +Q + ++R + + Q Sbjct: 586 NLQLAQLEAENQQLQSQVDGLAELQSQLKVLQQKYEQTLKINSDLSSRNQQLQQQLQNIQ 645 Query: 898 TQ-----LRDLESNLKRITHEHQTLIVQKKKEIEDLEIEF---NTQIESAIRDKKVLNEK 949 Q LRD + N++ + TL+ QK ++IEDL ++ QI++ + ++ Sbjct: 646 QQKNVNNLRDNQINIE--LQRNNTLLNQKSQQIEDLRLKLAKAEQQIDTLNNQLQNKQQE 703 Query: 950 YEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLEL-IDKHVQKQQTQSPDYTEQYI 1008 + I +L+ +++E ++ + NL ++ L N L D H+Q Q+ + +Q Sbjct: 704 LDNQIVLNAKLQDRIKELESELLNLKKTLQSLQDQNTSLKNDHHLQLQELREEILRKQ-- 761 Query: 1009 NEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVS 1068 EI L L Q E+ + N+ Q ++ + E KL T + + + Sbjct: 762 EEIKALQKLADQYKEKYLE-----NDRQ---LADLKGLERKLNDITIQKNQLADLNTAYQ 813 Query: 1069 KQLLDSKQHNEELQILVREQ---DDQIKELKE--TKLTFEMNIPKTEGMIISSTIEPMSD 1123 Q+ + N LQI ++E +DQ K+ + KL E + E ++ + Sbjct: 814 DQISKLQSENRSLQIKIQETHLFEDQNKQYEAIIEKLKAENTLKNKEITELNIKLPTYMQ 873 Query: 1124 DANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNT 1183 ++++ Q+ + + E L+++ L E++E K LE Sbjct: 874 QVSDLEKKLLRTD--------QQFQIYKNEVERLRQEKQNLIKEIEELKRKNKNLEQKVN 925 Query: 1184 ELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSI---SSAVDQRGFEIAELW- 1239 EL H QE I QL+ K +L + D L + I + + Q+ +I L+ Sbjct: 926 EL-NH---LQELIPQLEQKANRLQNQVDKLSKQNLDYNDQINLQNEQLSQQELQIRTLFQ 981 Query: 1240 -KQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKI-VTMEQVTSLQN 1297 K +L Q E+++ +L Q +K EQ + Q Q+ +++ +++ L+N Sbjct: 982 VKSNLQQLESNYSLVVQQLNDQ-RLQSAKLEQAFLNEQEQHQKTADELKKATKELDQLKN 1040 Query: 1298 KLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQ 1357 K++ E++++ L+ K + + IL E++ E + F +R EN+ Sbjct: 1041 KIEQLEKYIKELEGK----LIKDRILEQELK-EAIGF-------NLTLDTKLNQVRQENE 1088 Query: 1358 SYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIY 1417 S K I + EE Q K + +V AEA + + + EL D+ Sbjct: 1089 SLK----NEITQLKEELEQWK--AKYLQKDNEVKTLQVYKAEAIQMRIIND-ELTDNFNK 1141 Query: 1418 QKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQ 1477 ITL ++ E E+++QQ+ + ++RI +L + +++ L+ ++++ +Q Sbjct: 1142 LTKQLKAITLEKQIME-EDLQQQIADQKQRIAELE-QLVAQIEPLQTQVNDLQQLVNKLQ 1199 Query: 1478 KESEIERVKL------IEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEI 1531 E+++ KL ++EL KI + K +L E+ + L+ + Sbjct: 1200 NENKLLAKKLGEAQTKVKELESKIEAYEVMEKDYQKLQANYAEKAQDLRMTKEDLDKTTL 1259 Query: 1532 EIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAE 1588 ++ + E NL + +++I++ + KQ + ++L N N +L + V + E Sbjct: 1260 QLDKVTKEKENLDMRIAMLAAEIERQ-KHLNKNKQEKIDELTN-QNTDLSNVVAQLE 1314 Score = 145 bits (351), Expect = 1e-32 Identities = 239/1214 (19%), Positives = 518/1214 (42%), Gaps = 124/1214 (10%) Query: 144 VTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXX 203 + L+ T++ K A L K+K +E L++++ E +++ + + ++ Sbjct: 433 IDQLNRTLENKQQAYDKLNNKLKFVENDNNTLRQQVLEINEL-QIEKQSLLSELSSLDKE 491 Query: 204 XXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAA 263 + ++++ +QE + + E R I+ KD I+ L + K L Sbjct: 492 LKLKSEQLANVEKELQNLQEKLQQLRII-ELELNRAKSQIDMKDRDIAELRKQIKDLTVK 550 Query: 264 RFEIS----------LEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEK 313 FE+ E+ K+ Q+ E L ++ + + E + Sbjct: 551 NFELEQRLKELISKETEYLKIFQQCETYKSLNDQLNLQLAQLEAENQQLQSQVDGLAELQ 610 Query: 314 GSLEIANMT-ELTKKIEL-LEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLIS 371 L++ E T KI L N Q++Q + ++ + ++ ++ + L++ Sbjct: 611 SQLKVLQQKYEQTLKINSDLSSRNQQLQQQLQNIQQQKNVNNLRDNQINIELQRNNTLLN 670 Query: 372 RKSGRNTASKMKSPWSQLSSETLNQDTDKKINK--NEIAKLEMVIQSLNKDLVDKEYVIS 429 +KS + ++K ++ +TLN K + N+I L +Q K+L + +++ Sbjct: 671 QKSQQIEDLRLKLAKAEQQIDTLNNQLQNKQQELDNQIV-LNAKLQDRIKELESE--LLN 727 Query: 430 EKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQE- 488 K T K+ QLQ ++ + E++ + K+ +Q K++ Sbjct: 728 LKKTLQSLQDQNTSLKNDHHLQLQELREEILR---------KQEEIKALQKLADQYKEKY 778 Query: 489 LNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFS 548 L ++ + ++K L KL Q QL D A + K++S ++ +Q I Sbjct: 779 LENDRQLADLKGLERKLNDITIQKNQLADLNTAYQDQISKLQSENR----SLQIKIQETH 834 Query: 549 KVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENL 608 D NK+ + E+L ++ + +E L + L Y SD+ KK++ + Sbjct: 835 LFEDQNKQYEAIIEKLK--AENTLK-NKEITELNIKLPTY---MQQVSDLEKKLLRTDQQ 888 Query: 609 AETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQI 668 + + L +K +L++E+ L++K +E K+ +++ LQ E K+ L+ Q+ Sbjct: 889 FQIYKNEVERLRQEKQNLIKEIEELKRKNKNLEQKVNELNHLQELIPQLEQKANRLQNQV 948 Query: 669 DALSASKKEL--ALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEK 726 D LS + + ++N +L +++L I+ L K ++ NY L D ++ Sbjct: 949 DKLSKQNLDYNDQINLQNEQLSQQELQ--IRTLFQVKSNLQQLESNYSLVVQQLND--QR 1004 Query: 727 MSAEKISELLAKINHEEQ--------SKIQTQFG-IDAKIQERDLYIENIESELSKYKSR 777 + + K+ + A +N +EQ K + + KI++ + YI+ +E +L K + Sbjct: 1005 LQSAKLEQ--AFLNEQEQHQKTADELKKATKELDQLKNKIEQLEKYIKELEGKLIKDRIL 1062 Query: 778 ICRLEESIA---VMEDRRYSLERKADQLGS---YLQEKQKAYSEYTIQEDELVNRLAVLM 831 L+E+I ++ + + ++ + L + L+E+ + + +Q+D V L V Sbjct: 1063 EQELKEAIGFNLTLDTKLNQVRQENESLKNEITQLKEELEQWKAKYLQKDNEVKTLQVYK 1122 Query: 832 DHD---RVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDL 888 R++ +L + + NK ++ I LE+ QI D+QQ ++ + Sbjct: 1123 AEAIQMRIINDELTD--NFNKLTKQLKAITLEK----QIMEEDLQQQIADQKQRIAELEQ 1176 Query: 889 AESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNE 948 ++ QTQ+ DL+ + ++ +E++ L K++ + + + ++ES I +V+ + Sbjct: 1177 LVAQIEPLQTQVNDLQQLVNKLQNENKLLA----KKLGEAQTKVK-ELESKIEAYEVMEK 1231 Query: 949 KYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYI 1008 Y+K L+A Y ++L M E+L+K L+L DK V K++ Sbjct: 1232 DYQK-------LQAN---YAEKAQDLRMTKEDLDKTTLQL-DK-VTKEKENLDMRIAMLA 1279 Query: 1009 NEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVS 1068 EI + L K K E+I L + + L+ +LE ++ E R+S Sbjct: 1280 AEIERQKHLNKNKQEKIDELTNQ---------------NTDLSNVVAQLEPLDPENTRLS 1324 Query: 1069 KQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNV 1128 +Q+ + K+ ++ Q+ + ++DD+I +L + + ++ IE N Sbjct: 1325 EQIQEMKKKTDQDQLDLMKKDDEINKLNNEVYGLQNKVA-----LLGPEIERAKLKYNGA 1379 Query: 1129 DXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGH 1188 ++E EE +Q+ LQ++ L+ L + K+ LE N L Sbjct: 1380 QNT------------IKELEEKLQDYEHLQQELGNLDNALNQAEEKVQNLEKENNTLHQT 1427 Query: 1189 DVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREA 1248 +++NQ K+ + L + NLL+ + + + + Q+ E +L K+ + Q + Sbjct: 1428 LTAKSDELNQAKANVNDLQNQL-NLLNEQLINQQQLENELQQKDHENQQL-KEKIGQLQQ 1485 Query: 1249 DFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVT-SLQNKLQDKEEHLR 1307 ++ E +++ + +++++ Q NK+ E + L + L + ++H++ Sbjct: 1486 QIEQLE-QIKYDNEGKIAMLATQIEALKYKYQVAENKLKEQENIIGQLNDDLDNFDKHIQ 1544 Query: 1308 NLQEKYADVINQIE 1321 L+ + D+ ++++ Sbjct: 1545 ELEGENQDLKDKMQ 1558 Score = 142 bits (343), Expect = 9e-32 Identities = 258/1373 (18%), Positives = 575/1373 (41%), Gaps = 100/1373 (7%) Query: 216 QQMTKMQENFIAMEAEWKD-------EKQRLLKDIESKDVRISSLE-EANKLLEAARFEI 267 Q K EN +AM WKD ++ RLL+++ R++ L ++ K + + ++ Sbjct: 233 QSKIKNLENELAM---WKDKFKLSEEDRNRLLQELRELLERMNQLNLDSVKRGQLSTMDL 289 Query: 268 -SLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSL--EIANMTE- 323 E+ KL ++ Q L Q + + + L EI + + Sbjct: 290 LEDENKKLRDQINQILNDLDQWRKKALTLELQVFDLQVQVTDQDNNNKLLVKEIERLNQQ 349 Query: 324 LTKKIELLEHLNCQIRQTN---KELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTAS 380 L K + +E L ++Q KEL+ L E + V K+ + +++ N Sbjct: 350 LASKQQEIERLKTNLQQAEDHIKELQG-LKQQIQEKQRVIDELKRKNDEQAKQLLEN--E 406 Query: 381 KMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNK--DLVDKEYVISEKDTXXXXX 438 K+K Q+ + + +I +L +++ + D ++ + E D Sbjct: 407 KLKKQLEQIRGYNTDLQKQNGVLNYQIDQLNRTLENKQQAYDKLNNKLKFVENDNNTLRQ 466 Query: 439 XXXXXG-----KDTLIAQLQ-LEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDE 492 K +L+++L L+ + ++ L +V +++ E + ++ ELN Sbjct: 467 QVLEINELQIEKQSLLSELSSLDKELKLKSEQLANVEKELQNLQEKLQQLRIIELELNRA 526 Query: 493 IKDVNVKDL-IEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVS 551 +++KD I +L+ + +T N E++ K +I K LK+ Q +T + + Sbjct: 527 KSQIDMKDRDIAELRKQIKDLTVKNFELEQRLKELIS-KETEYLKIFQQCETYKSLN--D 583 Query: 552 DSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAET 611 N ++ +L E L +V L E + L++ Y+ I SD+ + +++ + Sbjct: 584 QLNLQLAQLEAENQQLQSQVDGLAELQSQLKVLQQKYEQTLKINSDLSSRNQQLQQQLQN 643 Query: 612 --RLKAISLLESQKFDLVQELH--ILQQKYDEVED---KLADISQLQSDQVCSEIKSVHL 664 + K ++ L + ++ + + +L QK ++ED KLA Q Q D + +++++ Sbjct: 644 IQQQKNVNNLRDNQINIELQRNNTLLNQKSQQIEDLRLKLAKAEQ-QIDTLNNQLQNK-- 700 Query: 665 EEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQE-NMDLTDK 723 ++++D +L I+ L+ + L T++ L++ + N +QE ++ K Sbjct: 701 QQELDNQIVLNAKLQDRIKELESELLNLKKTLQSLQDQNTSLKNDHHLQLQELREEILRK 760 Query: 724 LEKMSA-EKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLE 782 E++ A +K+++ + E ++ G++ K+ + + + + Y+ +I +L+ Sbjct: 761 QEEIKALQKLADQYKEKYLENDRQLADLKGLERKLNDITIQKNQLADLNTAYQDQISKLQ 820 Query: 783 ESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVN---RLAVLMDHDRVVEK 839 ++ + DQ Y +K +E T++ E+ +L M +EK Sbjct: 821 SENRSLQIKIQETHLFEDQNKQYEAIIEKLKAENTLKNKEITELNIKLPTYMQQVSDLEK 880 Query: 840 QLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQ 899 +LL + + + + + + L +E QNL + ++++ L +K N + + + + + Sbjct: 881 KLLRTDQQFQIYKNEVERLRQEKQNLIKEIEELKRKNKNLEQKVNELNHLQELIPQLEQK 940 Query: 900 LRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQ 959 L++ + +++ ++ Q + E L + QI + + K L ++ E N V Q Sbjct: 941 ANRLQNQVDKLSKQNLDYNDQINLQNEQLSQQ-ELQIRTLFQVKSNL-QQLESNYSLVVQ 998 Query: 960 LEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQK--QQTQSPDYTEQYINEIN-KL-- 1014 + +E +N +E ++ + + K ++ Q + E+YI E+ KL Sbjct: 999 QLNDQRLQSAKLEQAFLNEQEQHQKTADELKKATKELDQLKNKIEQLEKYIKELEGKLIK 1058 Query: 1015 NALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDS 1074 + +L+Q+ +E I N ++ ++++ Q +LE + + + ++ Sbjct: 1059 DRILEQELKEAIGFNLTLDTKLNQVRQENESLKNEITQLKEELEQWKAKYLQKDNEVKTL 1118 Query: 1075 KQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXX 1134 + + E I +R +D++ + KLT ++ E I+ ++ D Sbjct: 1119 QVYKAEA-IQMRIINDELTD-NFNKLTKQLKAITLEKQIMEEDLQQQIADQKQRIAELEQ 1176 Query: 1135 XXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQE 1194 L+ Q + Q + LQ ++ L +L E TK+ +LE+ ++ ++V+ ++ Sbjct: 1177 LVAQIEPLQTQVND-LQQLVNKLQNENKLLAKKLGEAQTKVKELES---KIEAYEVMEKD 1232 Query: 1195 ----QINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADF 1250 Q N + K + L ++L T +L ++ + IA L + Q+ + Sbjct: 1233 YQKLQANYAE-KAQDLRMTKEDLDKTTLQL-DKVTKEKENLDMRIAMLAAEIERQKHLNK 1290 Query: 1251 QKTEH--ELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSL-QNKLQDKEEHLR 1307 K E EL Q + + QL + + + +I M++ T Q L K++ + Sbjct: 1291 NKQEKIDELTNQNTDLSNVVAQL-EPLDPENTRLSEQIQEMKKKTDQDQLDLMKKDDEIN 1349 Query: 1308 NLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXX------DLRTENQSYKQ 1361 L + + N++ +L EIE K+ + +L + + Q Sbjct: 1350 KLNNEVYGLQNKVALLGPEIERAKLKYNGAQNTIKELEEKLQDYEHLQQELGNLDNALNQ 1409 Query: 1362 MQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQL---ELKDSEIYQ 1418 +E+ + N+ +EN L ++ VND + ++ L QL + ++E+ Q Sbjct: 1410 AEEK-VQNLEKENNTLHQTLTAKSDELNQAKANVNDLQNQLNLLNEQLINQQQLENELQQ 1468 Query: 1419 KTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQK 1478 K HE N + + QL + +++E + Y+ E ++A+L A E ++ Sbjct: 1469 KDHE--------NQQLKEKIGQLQQQIEQLEQIKYDNEGKIAML-------ATQIEALKY 1513 Query: 1479 ESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEI 1531 + ++ KL E+ N+ LN + +K ++E + +++ ++ Q I Sbjct: 1514 KYQVAENKLKEQENI----IGQLNDDLDNFDKHIQELEGENQDLKDKMQQQSI 1562 Score = 116 bits (280), Expect = 4e-24 Identities = 231/1198 (19%), Positives = 514/1198 (42%), Gaps = 118/1198 (9%) Query: 213 DTKQQMTKMQENFIAMEAEWKDEKQRLL---KDIESKDVRISSLEEANKLLEAARFEISL 269 D + Q+T N + E + Q+L ++IE + E+ K L+ + +I Sbjct: 324 DLQVQVTDQDNNNKLLVKEIERLNQQLASKQQEIERLKTNLQQAEDHIKELQGLKQQIQ- 382 Query: 270 EHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIE 329 E ++ EL++ L KQ +E T+++++ + + +L + +E Sbjct: 383 EKQRVIDELKRKNDEQAKQLLENEKLKKQ-LEQIRGYNTDLQKQNGVLNYQIDQLNRTLE 441 Query: 330 LLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQL 389 + ++ K +EN T+ + ++ + L+S S + K+KS QL Sbjct: 442 NKQQAYDKLNNKLKFVENDNNTLRQQVLEINELQIEKQSLLSELSSLDKELKLKS--EQL 499 Query: 390 SS-ETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTL 448 ++ E Q+ +K+ + I +LE+ D+ D++ I+E + Sbjct: 500 ANVEKELQNLQEKLQQLRIIELELNRAKSQIDMKDRD--IAELRKQIKDLTVKNFELEQR 557 Query: 449 IAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQ-EQLKQELNDEIKDV-NVKDLIEKLK 506 + +L + ++++ + D + Q E Q+L ++ + ++ ++ L+ Sbjct: 558 LKELISKETEYLKIFQQCETYKSLNDQLNLQLAQLEAENQQLQSQVDGLAELQSQLKVLQ 617 Query: 507 SAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFS------KVSDSNKEIVRL 560 EQ ++N ++ + N+ + +L+ Q QK ++N ++ +N + + Sbjct: 618 QKYEQTLKINSDLSSRNQQL-----QQQLQNIQQQKNVNNLRDNQINIELQRNNTLLNQK 672 Query: 561 TEELHHLSQKVAELEEE----KGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAI 616 ++++ L K+A+ E++ LQ + D+ ++ + + ++ E+E+ K + Sbjct: 673 SQQIEDLRLKLAKAEQQIDTLNNQLQNKQQELDNQIVLNAKLQDRIKELESELLNLKKTL 732 Query: 617 SLLESQKFDLVQELHI-LQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASK 675 L+ Q L + H+ LQ+ +E+ K +I LQ ++ + K +LE D A Sbjct: 733 QSLQDQNTSLKNDHHLQLQELREEILRKQEEIKALQ--KLADQYKEKYLEN--DRQLADL 788 Query: 676 KELALVIENLKLDKEQL-------YGTIKDLENDKEDIMNKLQN---YIQENMDLTDKLE 725 K L + ++ + K QL I L+++ + K+Q + +N +E Sbjct: 789 KGLERKLNDITIQKNQLADLNTAYQDQISKLQSENRSLQIKIQETHLFEDQNKQYEAIIE 848 Query: 726 KMSAEKI--SELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEE 783 K+ AE ++ + ++N + + +Q ++ K+ D + ++E+ + + L + Sbjct: 849 KLKAENTLKNKEITELNIKLPTYMQQVSDLEKKLLRTDQQFQIYKNEVERLRQEKQNLIK 908 Query: 784 SIAVMEDRRYSLERKADQLGSYLQE-----KQKAYSEYTIQEDELVNRLAVLMDHDRVVE 838 I ++ + +LE+K ++L ++LQE +QKA + Q D+L + D + Sbjct: 909 EIEELKRKNKNLEQKVNEL-NHLQELIPQLEQKA-NRLQNQVDKLSKQNLDYNDQINLQN 966 Query: 839 KQLLEIEHENKEL--QKKNQILLEENQNLQISLSDMQQHYNALVEKA--------NRTDL 888 +QL + E + + L K N LE N +L + + Q+ +A +E+A +T Sbjct: 967 EQLSQQELQIRTLFQVKSNLQQLESNYSLVVQQLNDQRLQSAKLEQAFLNEQEQHQKTAD 1026 Query: 889 AESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLE--IEFNTQIESAIRDKKVL 946 ++TK QL++ L++ E + +++ + ++L+ I FN +++ + + Sbjct: 1027 ELKKATKELDQLKNKIEQLEKYIKELEGKLIKDRILEQELKEAIGFNLTLDTKLNQVRQE 1086 Query: 947 NEKYEKNIEYVTQLEAQLQEYK-------NNIENLNMNVEE--------------LNKMN 985 NE + I TQL+ +L+++K N ++ L + E NK+ Sbjct: 1087 NESLKNEI---TQLKEELEQWKAKYLQKDNEVKTLQVYKAEAIQMRIINDELTDNFNKLT 1143 Query: 986 LEL----IDKHVQKQQTQSPDYTE-QYINEINKLNALLKQKDEEIIALNQKINNAQVSYM 1040 +L ++K + ++ Q + Q I E+ +L A ++ ++ L Q +N Q Sbjct: 1144 KQLKAITLEKQIMEEDLQQQIADQKQRIAELEQLVAQIEPLQTQVNDLQQLVNKLQNENK 1203 Query: 1041 SM---VSDYESKLAQFTTKLEN---MEEEMQRV----SKQLLDSKQHNEELQILVREQDD 1090 + + + ++K+ + +K+E ME++ Q++ +++ D + E+L + D Sbjct: 1204 LLAKKLGEAQTKVKELESKIEAYEVMEKDYQKLQANYAEKAQDLRMTKEDLDKTTLQLDK 1263 Query: 1091 QIKELKETKLTFEMNIPKTEGMI-ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEE 1149 KE + + M + E ++ + D+ N + L E Sbjct: 1264 VTKEKENLDMRIAMLAAEIERQKHLNKNKQEKIDELTNQNTDLSNVVAQLEPL--DPENT 1321 Query: 1150 FIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTE 1209 + E+ +QE K + + + K ++ LN E+ G Q ++ L ++E+ + Sbjct: 1322 RLSEQ--IQEMKKKTDQDQLDLMKKDDEINKLNNEVYGL----QNKVALLGPEIERAKLK 1375 Query: 1210 NDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYE 1269 + +T+ EL + + E+ L L Q E Q E E +K + Sbjct: 1376 YNGAQNTIKELEEKLQD-YEHLQQELGNL-DNALNQAEEKVQNLEKENNTLHQTLTAKSD 1433 Query: 1270 QLLDSVQSSTQEETNKIVTM-EQVTS---LQNKLQDKEEHLRNLQEKYADVINQIEIL 1323 +L + +++ + N++ + EQ+ + L+N+LQ K+ + L+EK + QIE L Sbjct: 1434 EL-NQAKANVNDLQNQLNLLNEQLINQQQLENELQQKDHENQQLKEKIGQLQQQIEQL 1490 Score = 100 bits (240), Expect = 3e-19 Identities = 200/1046 (19%), Positives = 456/1046 (43%), Gaps = 76/1046 (7%) Query: 91 SESLANTLKQKEILMEKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNT 150 SE LAN K+ + L EK++Q + + + + Q+ D+T + Sbjct: 496 SEQLANVEKELQNLQEKLQQLRIIELELNR--AKSQIDMKDRDIAELRKQIKDLTVKNFE 553 Query: 151 IKEKDNALSVLQVK-MKIME--TTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXX 207 ++++ L + + +KI + T L +++N + +EA+N+ Sbjct: 554 LEQRLKELISKETEYLKIFQQCETYKSLNDQLNLQLAQLEAENQQLQSQVDGLAELQSQL 613 Query: 208 XXXXEDTKQQMTKMQENFIAMEAEWKDEKQRL--LKDIES-KDVRIS-SLEEANKLLEAA 263 + +Q + K+ + + + + + Q + K++ + +D +I+ L+ N LL Sbjct: 614 KVLQQKYEQTL-KINSDLSSRNQQLQQQLQNIQQQKNVNNLRDNQINIELQRNNTLLNQK 672 Query: 264 RFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTE 323 +I KLA+ +Q L Q I + + + I+E S E+ N Sbjct: 673 SQQIEDLRLKLAKAEQQIDTLNNQLQNKQQELDNQ-IVLNAKLQDRIKELES-ELLN--- 727 Query: 324 LTKKIELLEHLNCQIRQTN----KELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTA 379 L K ++ L+ N ++ + +EL ++ E KA+ + + ++ R A Sbjct: 728 LKKTLQSLQDQNTSLKNDHHLQLQELREEILRKQEEIKALQKLADQYKEKY-LENDRQLA 786 Query: 380 SKMKSPWSQLSSETLNQDTDKKIN---KNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXX 436 +K +L+ T+ ++ +N +++I+KL+ +SL + + + ++ +++ Sbjct: 787 D-LKGLERKLNDITIQKNQLADLNTAYQDQISKLQSENRSL-QIKIQETHLFEDQNKQYE 844 Query: 437 XXXXXXXGKDTL----IAQLQLEHQQHMEGPS-LIHVGTNTEDVNEIAKVQ-EQLKQELN 490 ++TL I +L ++ +M+ S L T+ +I K + E+L+QE Sbjct: 845 AIIEKLKAENTLKNKEITELNIKLPTYMQQVSDLEKKLLRTDQQFQIYKNEVERLRQEKQ 904 Query: 491 DEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKV 550 + IK+ +++L K K+ E+++ +LN ++ ++ + K ++Q +D SK Sbjct: 905 NLIKE--IEELKRKNKNLEQKVNELN--------HLQELIPQLEQKANRLQNQVDKLSKQ 954 Query: 551 S-DSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLA 609 + D N +I E+L ++ L + K NLQ +Y ++ + + ++ L Sbjct: 955 NLDYNDQINLQNEQLSQQELQIRTLFQVKSNLQQLESNYS---LVVQQLNDQRLQSAKLE 1011 Query: 610 ETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQID 669 + L + Q EL ++ D++++K+ + + + IK LE+++ Sbjct: 1012 QAFLNE----QEQHQKTADELKKATKELDQLKNKIEQLEKYIKELEGKLIKDRILEQELK 1067 Query: 670 ALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSA 729 L + ++ + E L I L KE++ Y+Q++ ++ L+ A Sbjct: 1068 EAIGFNLTLDTKLNQVRQENESLKNEITQL---KEELEQWKAKYLQKDNEV-KTLQVYKA 1123 Query: 730 EKIS-ELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVM 788 E I ++ + +K+ Q + A E+ + E+++ +++ K RI LE+ +A + Sbjct: 1124 EAIQMRIINDELTDNFNKLTKQ--LKAITLEKQIMEEDLQQQIADQKQRIAELEQLVAQI 1181 Query: 789 EDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHEN 848 E + + QL + LQ + K ++ + V L ++ V+EK +++ Sbjct: 1182 EPLQTQV-NDLQQLVNKLQNENKLLAKKLGEAQTKVKELESKIEAYEVMEKDYQKLQANY 1240 Query: 849 KELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLK 908 E + ++ E+ + L + + L + AE E K+ ++ + + Sbjct: 1241 AEKAQDLRMTKEDLDKTTLQLDKVTKEKENLDMRIAML-AAEIERQKHLN--KNKQEKID 1297 Query: 909 RITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYE----KNIEYVTQLEAQL 964 +T+++ T + ++E L+ E NT++ I++ K ++ + K + + +L ++ Sbjct: 1298 ELTNQN-TDLSNVVAQLEPLDPE-NTRLSEQIQEMKKKTDQDQLDLMKKDDEINKLNNEV 1355 Query: 965 QEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEE 1024 +N + L +E K+ +++ + + DY E E+ L+ L Q +E+ Sbjct: 1356 YGLQNKVALLGPEIERA-KLKYNGAQNTIKELEEKLQDY-EHLQQELGNLDNALNQAEEK 1413 Query: 1025 IIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQIL 1084 + L +K NN ++ SD +L Q + +++ ++ +++QL++ +Q ELQ Sbjct: 1414 VQNL-EKENNTLHQTLTAKSD---ELNQAKANVNDLQNQLNLLNEQLINQQQLENELQ-- 1467 Query: 1085 VREQDDQIKELKETKLTFEMNIPKTE 1110 ++D + ++LKE + I + E Sbjct: 1468 --QKDHENQQLKEKIGQLQQQIEQLE 1491 Score = 98.3 bits (234), Expect = 2e-18 Identities = 169/850 (19%), Positives = 385/850 (45%), Gaps = 69/850 (8%) Query: 174 DLQEKINEKDQIIEAKNK-ATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIA-MEAE 231 +L+E+I K + I+A K A + K +Q+N +A + Sbjct: 752 ELREEILRKQEEIKALQKLADQYKEKYLENDRQLADLKGLERKLNDITIQKNQLADLNTA 811 Query: 232 WKDEKQRLLKDIESKDVRISS---LEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXX 288 ++D+ +L + S ++I E+ NK EA ++ E++ +E+ + Sbjct: 812 YQDQISKLQSENRSLQIKIQETHLFEDQNKQYEAIIEKLKAENTLKNKEITELNIKLPTY 871 Query: 289 XXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENK 348 L K+ + +++ +I + E+ + + +K L++ + ++++ NK LE K Sbjct: 872 MQQVSDLEKKLLRT--DQQFQIYKN---EVERLRQ--EKQNLIKEIE-ELKRKNKNLEQK 923 Query: 349 LATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIA 408 + + + + P + +K A+++++ +LS + L+ + + +++ Sbjct: 924 VNELNHLQELI--------PQLEQK-----ANRLQNQVDKLSKQNLDYNDQINLQNEQLS 970 Query: 409 KLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHV 468 + E+ I++L + + + + S L E +QH + + Sbjct: 971 QQELQIRTLFQVKSNLQQLESNYSLVVQQLNDQRLQSAKLEQAFLNEQEQHQKTADELKK 1030 Query: 469 GTNTEDV--NEIAKVQEQLKQE----LNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAA 522 T D N+I ++++ +K+ + D I + +K+ I + + ++ Q+ E ++ Sbjct: 1031 ATKELDQLKNKIEQLEKYIKELEGKLIKDRILEQELKEAIGFNLTLDTKLNQVRQENESL 1090 Query: 523 NKNMIKVKSN-HKLKLKQMQKTIDNFSKVSDSNK-EIVRLTEELHHLSQKVAELEEEKG- 579 + ++K + K K +QK DN K K E +++ L+ +L ++ Sbjct: 1091 KNEITQLKEELEQWKAKYLQK--DNEVKTLQVYKAEAIQMRIINDELTDNFNKLTKQLKA 1148 Query: 580 -NLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYD 638 L+ +++ D + I +D +++ E+E L + I L++Q DL Q ++ LQ + Sbjct: 1149 ITLEKQIMEEDLQQQI-ADQKQRIAELEQL----VAQIEPLQTQVNDLQQLVNKLQNENK 1203 Query: 639 EVEDKLADISQLQSDQVCSEIKSVH-LEEQIDALSASKKELALVIENLKLDKEQLYGTIK 697 + KL + +Q + ++ S+I++ +E+ L A+ E A ++L++ KE L T Sbjct: 1204 LLAKKLGE-AQTKVKELESKIEAYEVMEKDYQKLQANYAEKA---QDLRMTKEDLDKTTL 1259 Query: 698 DLEN---DKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGID 754 L+ +KE++ ++ E ++ L K EKI EL + N + + + +D Sbjct: 1260 QLDKVTKEKENLDMRIAMLAAE-IERQKHLNKNKQEKIDELTNQ-NTDLSNVVAQLEPLD 1317 Query: 755 AKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYS 814 + I+ ++ + + + + + ++ I + + Y L+ K LG ++ + Y+ Sbjct: 1318 PENTRLSEQIQEMKKKTDQDQLDLMKKDDEINKLNNEVYGLQNKVALLGPEIERAKLKYN 1377 Query: 815 EYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQ 874 EL +L D++ + +++L +++ + ++K Q L +EN L +L+ Sbjct: 1378 GAQNTIKELEEKL---QDYEHL-QQELGNLDNALNQAEEKVQNLEKENNTLHQTLTAKSD 1433 Query: 875 HYNALVEKANRTDLAESESTKYQTQL---RDLESNLKRITHEHQTL---IVQKKKEIEDL 928 N KAN DL +++ QL + LE+ L++ HE+Q L I Q +++IE L Sbjct: 1434 ELNQA--KANVNDL-QNQLNLLNEQLINQQQLENELQQKDHENQQLKEKIGQLQQQIEQL 1490 Query: 929 E-IEFNTQIESAIRDKKV--LNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMN 985 E I+++ + + A+ ++ L KY+ + + E + + ++++N + +++EL N Sbjct: 1491 EQIKYDNEGKIAMLATQIEALKYKYQVAENKLKEQENIIGQLNDDLDNFDKHIQELEGEN 1550 Query: 986 LELIDKHVQK 995 +L DK Q+ Sbjct: 1551 QDLKDKMQQQ 1560 Score = 75.8 bits (178), Expect = 9e-12 Identities = 125/587 (21%), Positives = 251/587 (42%), Gaps = 56/587 (9%) Query: 148 SNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXX 207 ++ +K+ L L+ K++ +E I +L+ K+ KD+I+E + K Sbjct: 1025 ADELKKATKELDQLKNKIEQLEKYIKELEGKLI-KDRILEQELKEAIGFNLTLDTKLNQV 1083 Query: 208 XXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEI 267 E K ++T+++E +WK + L KD E K +++ E + E+ Sbjct: 1084 RQENESLKNEITQLKEEL----EQWK--AKYLQKDNEVKTLQVYKAEAIQ--MRIINDEL 1135 Query: 268 SLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKK 327 + +KL ++L+ + + + ++K I E L +A + L + Sbjct: 1136 TDNFNKLTKQLK-------AITLEKQIMEEDLQQQIADQKQRIAELEQL-VAQIEPLQTQ 1187 Query: 328 IELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLIS--RKSGRNTASKMKSP 385 + L+ L +++ NK L KL T+ K + S + + +K N A K + Sbjct: 1188 VNDLQQLVNKLQNENKLLAKKLGEAQTKVKELESKIEAYEVMEKDYQKLQANYAEKAQD- 1246 Query: 386 WSQLSSETLNQDTDK--KINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXX 443 +++ E L++ T + K+ K E L+M I L ++ ++++ K Sbjct: 1247 -LRMTKEDLDKTTLQLDKVTK-EKENLDMRIAMLAAEIERQKHLNKNKQEKIDELTNQNT 1304 Query: 444 GKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIE 503 ++AQL+ E L +E + E+ K +Q + +L KD + L Sbjct: 1305 DLSNVVAQLE---PLDPENTRL------SEQIQEMKKKTDQDQLDLMK--KDDEINKLNN 1353 Query: 504 KLKSAEEQITQLNDEIDAANKNMIKVKSNHKLK-LKQMQKTIDNFSKVSDSNKEIVRLTE 562 ++ + ++ L EI+ A K+K N +K++++ + ++ + +E+ L Sbjct: 1354 EVYGLQNKVALLGPEIERA-----KLKYNGAQNTIKELEEKLQDYEHLQ---QELGNLDN 1405 Query: 563 ELHHLSQKVAELEEEKGNLQLHLV-DYDSGRMIESDVYKKMIEMENLAETRLKAISLLES 621 L+ +KV LE+E L L D +++V ++ NL +L LE+ Sbjct: 1406 ALNQAEEKVQNLEKENNTLHQTLTAKSDELNQAKANVNDLQNQL-NLLNEQLINQQQLEN 1464 Query: 622 QKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALV 681 + E L++K +++ ++ + Q++ D +E K L QI+AL + V Sbjct: 1465 ELQQKDHENQQLKEKIGQLQQQIEQLEQIKYD---NEGKIAMLATQIEALKYKYQ----V 1517 Query: 682 IENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMS 728 EN ++E + G + D D ++ +Q EN DL DK+++ S Sbjct: 1518 AENKLKEQENIIGQLND---DLDNFDKHIQELEGENQDLKDKMQQQS 1561 >UniRef50_A0BIQ2 Cluster: Chromosome undetermined scaffold_11, whole genome shotgun sequence; n=1; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_11, whole genome shotgun sequence - Paramecium tetraurelia Length = 2447 Score = 166 bits (403), Expect = 5e-39 Identities = 281/1420 (19%), Positives = 604/1420 (42%), Gaps = 113/1420 (7%) Query: 231 EWKDEKQRLLKDIESKDVRISSLEE-ANKLLEAARFEISLEHSKLAQE-LEQXXXXXXXX 288 E+ + Q+L K+I++ +++ EE N++++ + EI+ S+L Q+ LE+ Sbjct: 286 EYSKQIQQLNKEIQTYKQQLAQQEEQCNRIVQQKQKEINQVQSQLEQKHLEETLKKQQQN 345 Query: 289 XXXXXXLAKQ--SIEPSC----EEKTEIEEKGSLEIANMTELTKKIEL-LEHLNCQIRQT 341 + +Q S++ +E + +++K + N+ + K+++L L++L Sbjct: 346 EQQYLQVIEQFNSLQNKIALLEDENSSLKQKSFKTLKNVVQELKRMKLELQNLKMMGHYD 405 Query: 342 NKELEN-KLATMGTESKAVSSPSKKGS---PLISRKSGRNTASKMKSPWSQLSSETLNQD 397 +L + M +A+S P K ++ S + ++ +QL + + Sbjct: 406 ISQLNGLEQILMDQLEQAISQPHKNQEYMQEIVQEMSQEQSLTERTQVQNQLQLQLIKHK 465 Query: 398 TDKKINKNEIAKLEMVIQSLNKDL---------VDKEYVISEKDTXXXXXXXXXXGKDTL 448 K ++ E++ Q + L + ++ + D D+L Sbjct: 466 QVFKFILEDVCNSEVIKQQILNTLGQFKQFLLNIIQQQYLKSLDLMNNQKQDYSSQIDSL 525 Query: 449 IAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLK-QELNDEIKDVN-----VKDLI 502 I +L +QQ E + TN ++ + + + Q + Q L +I ++N + Sbjct: 526 IQELNNVNQQLFE---MQKQNTNLQEQIQSKQDEHQYEMQNLQGQIDNLNSILEETNQNL 582 Query: 503 EKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFS-KVSDSNKEIVRLT 561 EK + I ++I + + + K + + + I+ + K ++ N+ +L Sbjct: 583 EKDNQNQALIDHYQNQISQLETQLAQSQQQQKTQQQTLNTAIEQSNVKDAELNETKQKLN 642 Query: 562 EELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLES 621 L QK +L+ +K Q YD +++ + + E+E L +T+ K L + Sbjct: 643 SLNTLLKQKEEDLKMQKQLAQTKSTKYDQEKLLTQKLQQ---EIEAL-KTQNKQFQLDLN 698 Query: 622 QKFDL--VQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVH---------LEEQIDA 670 ++ DL Q+ + + K D + K LQ+ Q ++IKS L+EQ D Sbjct: 699 RQKDLNKQQQTDLGKLKADNQQLKQQSEQFLQTQQELTKIKSEFSKTLQEKNTLQEQFDE 758 Query: 671 LSASKKELALVIENLKLDKE---QLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKM 727 + S+ L + + L+ +++ +L + +L+ + E+ +++NY Q+N L +L+ + Sbjct: 759 VKKSQALLTTLNDELQEEQQINDKLKQQLLELQLEFENSKEQMENYSQDNERLKQQLKDL 818 Query: 728 SAEKISELLAKINHEEQ--SKIQTQFGIDAKIQER-DLYI-ENIESELSKYKSRICRLEE 783 + + L +EQ SK Q + ++ QE+ +L+ ++IE K K E Sbjct: 819 NNDYELTLQENQMLQEQIISKDQNLIQLQSQQQEQINLFCSQSIEQSDLKNKDLANSNES 878 Query: 784 SIAVMEDRRYSLERKADQLG---SYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQ 840 + + D + SLE+ + +G + +QE Q + + L N++ L ++ +++ Sbjct: 879 LQSQIYDLKLSLEQAQETIGQNQTSIQELQADSLKLKDENSTLKNQIQELSIKNQQIQES 938 Query: 841 L---LEI-EHENKELQKKNQILLEE---NQNLQISLSDMQQHYNALVEKANRTDLAESES 893 L + I +++ K +Q + L +E NQ I L+++ + + AL ++ D +E Sbjct: 939 LETQMSISQNQEKLIQNQTSQLEQEQVNNQRQGIQLTNLNKKFEALEQQLESKDQELNEY 998 Query: 894 TKYQTQLR----DLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEK 949 + L+ E L + + E Q+ Q + E + ++ N + +K L E Sbjct: 999 IQQTNYLKIKNEQSEQQLFKQSQELQSNKSQNQSSNESI-VQLNELVNHLREGEKQLQES 1057 Query: 950 YEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYIN 1009 ++ +Q++ QL+E + ++NL +E +N L+ + + QTQS Sbjct: 1058 VKEIQNQKSQIQKQLEEKEQLLQNLQ---QENKNLNAALLAEK-SENQTQSEQIRSLQNE 1113 Query: 1010 EINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSK 1069 I K+N + ++++ Q+ NN Y +S Y+ + + L+ E+ Q Sbjct: 1114 LIQKINETTLENEKQLQLNIQQQNNKIQQYELQISKYKQQNENLNSNLQEAEKHKQLDKN 1173 Query: 1070 QLLDSKQHNEELQILVREQDDQIKELKETKLTFE-------MNIPKTEGMIISSTIEPMS 1122 Q+ + Q+ +ELQ ++ Q QI+E K+ + + I + + I S +++ S Sbjct: 1174 QIAELNQNIQELQRNLQSQLSQIEESKQQNNQKDQQIQQLLLKIDEQKSQIESISLQLQS 1233 Query: 1123 DDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLN 1182 + N ++ ++++++ I + L++ K +E ++ +I++LE Sbjct: 1234 EKKNLLEDNDVLKNANQQLQGLEQQQQTIIAQ--LKQDYEKKISEQKDLENQILKLEQNY 1291 Query: 1183 TELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQH 1242 + + Q +NQ + + EQ E N L L + + Q E + Sbjct: 1292 QNESSNRQTIQNSLNQQREENEQNQQELKNRLIQNQSLIEEVDTLKQQHLLNQEE--NLN 1349 Query: 1243 LAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKI-VTMEQVTSLQNKLQD 1301 L + D + E +R E Q + + + +E N + + +Q+ +Q + Sbjct: 1350 LQTQLKDLTQEEQNIRANARQQEQIQNQKIQELINENREAQNLVEILQKQIVQIQ---YE 1406 Query: 1302 KEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQ 1361 KE+ L EK Q++ +EIED+K F + + Sbjct: 1407 KEKIEEELSEKNL----QLDNYSNEIEDQKTQFLQKIEILQQNQQILEIQKKQTDNEILN 1462 Query: 1362 MQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTH 1421 Q Q I +N++N QL+ + E ++ E QL+LK+ EI ++ Sbjct: 1463 YQNQ-IEKLNQDNLQLQNELKVLSSNIQKDIDSMK--EKQIAEKDAQLQLKNQEI-KELK 1518 Query: 1422 EYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESE 1481 E I L ++ ++ Q+ + ++ + E + +L L + +++ +T ++E + Sbjct: 1519 EKNIQLDEKMKLIGELQNQIRQTNEKFQ----ENQQKLQELEITINQLNQGIQTKEQECQ 1574 Query: 1482 IERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEIT 1541 E +K EL ++ + NK++ + L+EE+++ N +N++ T+ DE+ Sbjct: 1575 -ESLKKSRELEDRLLVAQQENKKLISSVENLQEEISQKN------QNEQ----TIQDELK 1623 Query: 1542 NLQNMV-RASSSKI-QKHVSFASDTKQGRDEQLDNTMNKE 1579 Q V + KI Q+ + +T+ EQ + +N E Sbjct: 1624 QFQQEVSKIKEEKILQESEIISKNTQLNLQEQKISQLNDE 1663 Score = 155 bits (376), Expect = 1e-35 Identities = 293/1513 (19%), Positives = 650/1513 (42%), Gaps = 144/1513 (9%) Query: 90 ISESLANTLKQ-KEILMEKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTH-L 147 I + + NTL Q K+ L+ I+Q S ++ +L +V L Sbjct: 481 IKQQILNTLGQFKQFLLNIIQQ----QYLKSLDLMNNQKQDYSSQIDSLIQELNNVNQQL 536 Query: 148 SNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXX 207 K+ N +Q K + + +LQ +I+ + I+E N+ Sbjct: 537 FEMQKQNTNLQEQIQSKQDEHQYEMQNLQGQIDNLNSILEETNQ--------NLEKDNQN 588 Query: 208 XXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEI 267 + + Q+++++ + + K ++Q L IE +V+ + L E + L + + Sbjct: 589 QALIDHYQNQISQLETQLAQSQQQQKTQQQTLNTAIEQSNVKDAELNETKQKLNSLNTLL 648 Query: 268 SLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKK 327 + L ++++ L Q ++ E ++ L++ +L K+ Sbjct: 649 KQKEEDL--KMQKQLAQTKSTKYDQEKLLTQKLQQEIEALKTQNKQFQLDLNRQKDLNKQ 706 Query: 328 IEL-LEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPW 386 + L L +Q ++ E L T +K S SK L + + + ++K Sbjct: 707 QQTDLGKLKADNQQLKQQSEQFLQTQQELTKIKSEFSKT---LQEKNTLQEQFDEVKK-- 761 Query: 387 SQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKD 446 SQ TLN + ++ N+ K +++ L + ++ +D D Sbjct: 762 SQALLTTLNDELQEEQQINDKLKQQLLELQLEFENSKEQMENYSQDNERLKQQLKDLNND 821 Query: 447 TLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLK 506 +L L+ Q ++ +I N + + Q L + E D+ KDL + Sbjct: 822 Y---ELTLQENQMLQ-EQIISKDQNLIQLQSQQQEQINLFCSQSIEQSDLKNKDLANSNE 877 Query: 507 SAEEQITQLNDEIDAA------NKNMIKVKSNHKLKLKQMQKTIDN-FSKVSDSNKEIVR 559 S + QI L ++ A N+ I+ LKLK T+ N ++S N++I Sbjct: 878 SLQSQIYDLKLSLEQAQETIGQNQTSIQELQADSLKLKDENSTLKNQIQELSIKNQQIQE 937 Query: 560 LTEELHHLSQKVAEL-EEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISL 618 E +SQ +L + + L+ V+ + +++ KK +E E++ + ++ Sbjct: 938 SLETQMSISQNQEKLIQNQTSQLEQEQVNNQRQGIQLTNLNKKFEALEQQLESKDQELN- 996 Query: 619 LESQKFDLVQELHILQQKYDEVEDKLADISQ-LQSDQVCSEIKS---VHLEEQIDALSAS 674 + +Q+ + L+ K ++ E +L SQ LQS++ ++ + V L E ++ L Sbjct: 997 ------EYIQQTNYLKIKNEQSEQQLFKQSQELQSNKSQNQSSNESIVQLNELVNHLREG 1050 Query: 675 KKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKL--EKMSAEKI 732 +K+L ++ ++ K Q+ K LE +KE ++ LQ QEN +L L EK + Sbjct: 1051 EKQLQESVKEIQNQKSQIQ---KQLE-EKEQLLQNLQ---QENKNLNAALLAEKSENQTQ 1103 Query: 733 SELLAKINHE-----EQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAV 787 SE + + +E ++ ++ + + IQ+++ I+ E ++SKYK + L ++ Sbjct: 1104 SEQIRSLQNELIQKINETTLENEKQLQLNIQQQNNKIQQYELQISKYKQQNENLNSNLQE 1163 Query: 788 MEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHE 847 E + + + +L +QE Q+ Q +E + D+ +++ LL+I+ + Sbjct: 1164 AEKHKQLDKNQIAELNQNIQELQRNLQSQLSQIEESKQQNN---QKDQQIQQLLLKIDEQ 1220 Query: 848 NKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNL 907 +++ + L E +NL L D N +++ AN+ + + QT + L+ + Sbjct: 1221 KSQIESISLQLQSEKKNL---LED-----NDVLKNANQQ--LQGLEQQQQTIIAQLKQDY 1270 Query: 908 KRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRD--KKVLNEKYEKNIEYVTQLEAQLQ 965 ++ E QK E + L++E N Q ES+ R + LN++ E+N + +L+ +L Sbjct: 1271 EKKISE------QKDLENQILKLEQNYQNESSNRQTIQNSLNQQREENEQNQQELKNRLI 1324 Query: 966 EYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEI 1025 + ++ IE V+ L + +L L + QTQ D T++ N + A +Q+++ Sbjct: 1325 QNQSLIEE----VDTLKQQHL-LNQEENLNLQTQLKDLTQEEQN----IRANARQQEQIQ 1375 Query: 1026 IALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILV 1085 Q++ N ++V + ++ Q + E +EEE+ + QL ++ E++ Sbjct: 1376 NQKIQELINENREAQNLVEILQKQIVQIQYEKEKIEEELSEKNLQL---DNYSNEIEDQK 1432 Query: 1086 REQDDQIKELKETKLTFEMNIPKTEGMIIS--STIEPMSDDANNVDXXXXXXXXXXXXLK 1143 + +I+ L++ + E+ +T+ I++ + IE ++ D + Sbjct: 1433 TQFLQKIEILQQNQQILEIQKKQTDNEILNYQNQIEKLNQDNLQLQNELKVLSS-----N 1487 Query: 1144 VQEEEEFIQERSVLQEQSAKL---NTELQECYTKIIQLETLNTELTGHDVVNQEQINQLK 1200 +Q++ + ++E+ + E+ A+L N E++E K IQL+ +L G Q QI Q Sbjct: 1488 IQKDIDSMKEKQIA-EKDAQLQLKNQEIKELKEKNIQLDE-KMKLIGE---LQNQIRQTN 1542 Query: 1201 SKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQ 1260 K ++ + L T+ +L I + K+ Q K EL + Sbjct: 1543 EKFQENQQKLQELEITINQLNQGIQT-------------KEQECQESL---KKSRELEDR 1586 Query: 1261 LSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQI 1320 L + + ++L+ SV++ QEE ++ EQ ++Q++L+ ++ + ++E+ ++ + Sbjct: 1587 LLVAQQENKKLISSVEN-LQEEISQKNQNEQ--TIQDELKQFQQEVSKIKEE--KILQES 1641 Query: 1321 EILRSE----IEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINE--EN 1374 EI+ ++++K++ D+ + Q ++Q+Q +N Sbjct: 1642 EIISKNTQLNLQEQKISQLNDEKDYLKTQMNEGKDMLKDLQQKLELQQQRQQKYEALVKN 1701 Query: 1375 AQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEF 1434 +LK +VN +K+ ++E +++ E+ Q+ Sbjct: 1702 EELKYLQKIENLETELSSQQVN---SKL-----KIENAKRKLHSILIEFGKCKRQQQHST 1753 Query: 1435 ENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVK 1494 ++ QLV++ K + + + +L+++ ++ + +++ + ++ VK+ ++ Sbjct: 1754 NFIKDQLVKFNKTYQTILVKLVKKLSVINSQIAQLKLNHQELDDMLRVQ-VKINPQIYKH 1812 Query: 1495 ITESVSLNKQVAE-LNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSK 1553 + + + V + + +++ +++ M A EN++ EI +L+ + ++L+N ++ ++ K Sbjct: 1813 LNQLQQQQESVVKSFKEKIQQLMSQQENMLFADENRKQEIQSLSTDRSDLKNQLQETNQK 1872 Query: 1554 IQKHVSFASDTKQ 1566 +Q+ + K+ Sbjct: 1873 LQQQQQINLELKE 1885 Score = 154 bits (374), Expect = 2e-35 Identities = 281/1418 (19%), Positives = 600/1418 (42%), Gaps = 131/1418 (9%) Query: 216 QQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANK---LLEAARFEISLEHS 272 QQ+ + E F+ + E K K ++ K+ +E K LL E+ E Sbjct: 719 QQLKQQSEQFLQTQQELTKIKSEFSKTLQEKNTLQEQFDEVKKSQALLTTLNDELQ-EEQ 777 Query: 273 KLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLE 332 ++ +L+Q +K+ +E ++ ++++ ++ N ELT ++ + Sbjct: 778 QINDKLKQQLLELQLEFEN----SKEQMENYSQDNERLKQQ-LKDLNNDYELT--LQENQ 830 Query: 333 HLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSE 392 L QI ++ L + + S S + S L ++ A+ +S SQ+ Sbjct: 831 MLQEQIISKDQNLIQLQSQQQEQINLFCSQSIEQSDL----KNKDLANSNESLQSQIYDL 886 Query: 393 TLN-QDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQ 451 L+ + + I +N+ + E+ SL L D+ + + I + Sbjct: 887 KLSLEQAQETIGQNQTSIQELQADSLK--LKDENSTLKNQ-----------------IQE 927 Query: 452 LQLEHQQHMEG-PSLIHVGTNTEDVNEIAKVQEQLKQE-LNDEIKDVNVKDLIEKLKSAE 509 L +++QQ E + + + N E + I QL+QE +N++ + + + +L +K ++ E Sbjct: 928 LSIKNQQIQESLETQMSISQNQEKL--IQNQTSQLEQEQVNNQRQGIQLTNLNKKFEALE 985 Query: 510 EQI----TQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELH 565 +Q+ +LN+ I N IK + + + KQ Q+ N S+ SN+ IV+L E ++ Sbjct: 986 QQLESKDQELNEYIQQTNYLKIKNEQSEQQLFKQSQELQSNKSQNQSSNESIVQLNELVN 1045 Query: 566 HLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLE-SQKF 624 HL + +L+E +Q ++ E + + ++ EN L A L E S+ Sbjct: 1046 HLREGEKQLQESVKEIQNQKSQIQK-QLEEKEQLLQNLQQEN---KNLNAALLAEKSENQ 1101 Query: 625 DLVQELHILQQKYDEV--EDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVI 682 +++ LQ + + E L + QLQ + K E QI + L + Sbjct: 1102 TQSEQIRSLQNELIQKINETTLENEKQLQLNIQQQNNKIQQYELQISKYKQQNENLNSNL 1161 Query: 683 ENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHE 742 + + K+ I +L + +++ LQ+ + + ++ + + ++I +LL KI+ E Sbjct: 1162 QEAEKHKQLDKNQIAELNQNIQELQRNLQSQLSQ-IEESKQQNNQKDQQIQQLLLKID-E 1219 Query: 743 EQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLE-ESIAVMEDRRYSLERKADQ 801 ++S+I++ + + ++++L +N L ++ LE + ++ + E+K + Sbjct: 1220 QKSQIES-ISLQLQSEKKNLLEDN--DVLKNANQQLQGLEQQQQTIIAQLKQDYEKKISE 1276 Query: 802 ---LGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQK----- 853 L + + + ++ Y + + N L + + +++L +N+ L + Sbjct: 1277 QKDLENQILKLEQNYQNESSNRQTIQNSLNQQREENEQNQQELKNRLIQNQSLIEEVDTL 1336 Query: 854 KNQILL--EENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRIT 911 K Q LL EEN NLQ L D+ Q + A + + +++ + NL I Sbjct: 1337 KQQHLLNQEENLNLQTQLKDLTQEEQNIRANARQQEQIQNQKIQELINENREAQNLVEIL 1396 Query: 912 HEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQ----LEAQLQEY 967 + I +K++IE+ E N Q+++ + + ++ + IE + Q LE Q ++ Sbjct: 1397 QKQIVQIQYEKEKIEEELSEKNLQLDNYSNEIEDQKTQFLQKIEILQQNQQILEIQKKQT 1456 Query: 968 KNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIA 1027 N I N +E+LN+ NL+L ++ D +I + +A L+ K++EI Sbjct: 1457 DNEILNYQNQIEKLNQDNLQLQNELKVLSSNIQKDIDSMKEKQIAEKDAQLQLKNQEIKE 1516 Query: 1028 LNQKINNAQV-SYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVR 1086 L +K N Q+ M ++ + ++++ Q K + ++++Q + + Q N+ +Q + Sbjct: 1517 LKEK--NIQLDEKMKLIGELQNQIRQTNEKFQENQQKLQELE---ITINQLNQGIQ--TK 1569 Query: 1087 EQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQE 1146 EQ+ Q K +L + + + E + S++E + ++ + + + Q+ Sbjct: 1570 EQECQESLKKSRELEDRLLVAQQENKKLISSVENLQEEISQKNQNEQTIQDELK--QFQQ 1627 Query: 1147 EEEFIQERSVLQE-QSAKLNTELQECYTKIIQL----ETLNTELT-GHDVVN--QEQI-- 1196 E I+E +LQE + NT+L KI QL + L T++ G D++ Q+++ Sbjct: 1628 EVSKIKEEKILQESEIISKNTQLNLQEQKISQLNDEKDYLKTQMNEGKDMLKDLQQKLEL 1687 Query: 1197 -NQLKSKLEQL-NTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTE 1254 Q + K E L E L + L + +SS +I E K+ L +F K + Sbjct: 1688 QQQRQQKYEALVKNEELKYLQKIENLETELSSQQVNSKLKI-ENAKRKLHSILIEFGKCK 1746 Query: 1255 HE-------LRVQLSAFESKYEQLLDSVQSSTQEETNKIV-------TMEQVTSLQNKLQ 1300 + ++ QL F Y+ +L + ++I ++ + +Q K+ Sbjct: 1747 RQQQHSTNFIKDQLVKFNKTYQTILVKLVKKLSVINSQIAQLKLNHQELDDMLRVQVKIN 1806 Query: 1301 DK-EEHLRNLQEKYADVINQI--EILRSEIEDEKVAFX-XXXXXXXXXXXXXXXDLRTEN 1356 + +HL LQ++ V+ +I + + E + F DL+ + Sbjct: 1807 PQIYKHLNQLQQQQESVVKSFKEKIQQLMSQQENMLFADENRKQEIQSLSTDRSDLKNQL 1866 Query: 1357 QSYK---QMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAK----------VL 1403 Q Q Q+Q L + EE +L+ + ++ K + Sbjct: 1867 QETNQKLQQQQQINLELKEEIQRLESQNLLYQGQIQEKNSAIDQQNEKCKLIPNLKNEIQ 1926 Query: 1404 ELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQ----LVEYEKRIEDLTYE-KESE 1458 +L Q + + + I + + +T+ + ++ +++++Q L E + +D+ + ++ E Sbjct: 1927 QLEQQRQRQQTMINEIQASFQVTIDHQQEQIQSLKEQNRDLLSGQEIKTQDIYLKLQKLE 1986 Query: 1459 LAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAK 1518 +++ K + K+ EI++++L + N ++E +L +LN +E + Sbjct: 1987 QQLIKEKQFSQQIFDKLSSKDEEIQQLQLAQRKN--LSEIDNLTNINEDLNDKIENLKDQ 2044 Query: 1519 TNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQK 1556 T Q +E I L + + N + K+ + Sbjct: 2045 TQRFQVYFSEKEETIRNLKETVYNQNLQLEEKGKKLNQ 2082 Score = 140 bits (339), Expect = 3e-31 Identities = 251/1394 (18%), Positives = 584/1394 (41%), Gaps = 108/1394 (7%) Query: 147 LSNTIKEKDNALSVLQVKMKIMETTILDLQ-EKINEKDQIIEAKNKATTXXXXXXXXXXX 205 L ++KE N S +Q +++ E + +LQ E N ++ K++ T Sbjct: 1054 LQESVKEIQNQKSQIQKQLEEKEQLLQNLQQENKNLNAALLAEKSENQTQSEQIRSLQNE 1113 Query: 206 XXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARF 265 E T + ++Q N + + + ++ K + + S+L+EA K + + Sbjct: 1114 LIQKINETTLENEKQLQLNIQQQNNKIQQYELQISKYKQQNENLNSNLQEAEKHKQLDKN 1173 Query: 266 EISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEE-KGSLEIANMTEL 324 +I+ E ++ QEL++ Q + + +I+E K +E ++ Sbjct: 1174 QIA-ELNQNIQELQRNLQSQLSQIEESKQQNNQKDQQIQQLLLKIDEQKSQIESISLQLQ 1232 Query: 325 TKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKS 384 ++K LLE N ++ N++L+ T + +K + +K N K++ Sbjct: 1233 SEKKNLLED-NDVLKNANQQLQGLEQQQQTIIAQLKQDYEK--KISEQKDLENQILKLEQ 1289 Query: 385 PWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXG 444 + SS N+ T + + + E Q L L+ + +I E DT Sbjct: 1290 NYQNESS---NRQTIQNSLNQQREENEQNQQELKNRLIQNQSLIEEVDTLKQQHLLNQ-- 1344 Query: 445 KDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDE-IKDVNVKDLIE 503 ++ L Q QL+ E I ++ + K+QE + + + + ++ K +++ Sbjct: 1345 EENLNLQTQLKDLTQEE--QNIRANARQQEQIQNQKIQELINENREAQNLVEILQKQIVQ 1402 Query: 504 ---KLKSAEEQITQLNDEIDAANKNMIKVKSN--HKLKLKQMQKTIDNFSKVSDSNKEIV 558 + + EE++++ N ++D + + K+ K+++ Q + I K N EI+ Sbjct: 1403 IQYEKEKIEEELSEKNLQLDNYSNEIEDQKTQFLQKIEILQQNQQILEIQKKQTDN-EIL 1461 Query: 559 RLTEELHHLSQKVAELEEE----KGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLK 614 ++ L+Q +L+ E N+Q + ++ E D ++ E + E + K Sbjct: 1462 NYQNQIEKLNQDNLQLQNELKVLSSNIQKDIDSMKEKQIAEKDAQLQLKNQE-IKELKEK 1520 Query: 615 AISLLESQKF--DLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALS 672 I L E K +L ++ +K+ E + KL ++ ++ +Q+ I++ E Q ++L Sbjct: 1521 NIQLDEKMKLIGELQNQIRQTNEKFQENQQKLQEL-EITINQLNQGIQTKEQECQ-ESLK 1578 Query: 673 ASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNY--IQENM-DLTDKLEKMSA 729 S++ + + L + +++ I +EN +E+I K QN IQ+ + ++ K+ Sbjct: 1579 KSRE----LEDRLLVAQQENKKLISSVENLQEEISQKNQNEQTIQDELKQFQQEVSKIKE 1634 Query: 730 EKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVME 789 EKI + I+ Q +Q Q KI + + + +++++++ K + L++ + + + Sbjct: 1635 EKILQESEIISKNTQLNLQEQ-----KISQLNDEKDYLKTQMNEGKDMLKDLQQKLELQQ 1689 Query: 790 DRRYSLER--KADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHE 847 R+ E K ++L YLQ+ + +E + Q+ VN + + R + L+E Sbjct: 1690 QRQQKYEALVKNEEL-KYLQKIENLETELSSQQ---VNSKLKIENAKRKLHSILIEFGKC 1745 Query: 848 NKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNL 907 ++ Q + ++Q ++ + + + LV+ + + S+ + + ++L+ L Sbjct: 1746 KRQQQHSTNFI--KDQLVKFN----KTYQTILVKLVKKLSVINSQIAQLKLNHQELDDML 1799 Query: 908 K---RITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQL 964 + +I + + Q +++ E + F +I+ + ++ + E + + L Sbjct: 1800 RVQVKINPQIYKHLNQLQQQQESVVKSFKEKIQQLMSQQENMLFADENRKQEIQSLSTDR 1859 Query: 965 QEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQY------INEINKLNALL 1018 + KN ++ N +++ ++NLEL ++ +Q+ ++Q+ Y Q I++ N+ L+ Sbjct: 1860 SDLKNQLQETNQKLQQQQQINLELKEE-IQRLESQNLLYQGQIQEKNSAIDQQNEKCKLI 1918 Query: 1019 KQKDEEIIALNQK-------INNAQVSYMSMVSDYESKLAQFTT-----------KLENM 1060 EI L Q+ IN Q S+ + + ++ K +++ Sbjct: 1919 PNLKNEIQQLEQQRQRQQTMINEIQASFQVTIDHQQEQIQSLKEQNRDLLSGQEIKTQDI 1978 Query: 1061 EEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEP 1120 ++Q++ +QL+ KQ ++++ + +D++I++L+ L N+ + + + ++ E Sbjct: 1979 YLKLQKLEQQLIKEKQFSQQIFDKLSSKDEEIQQLQ---LAQRKNLSEIDNL--TNINED 2033 Query: 1121 MSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLET 1180 ++D N+ + E+EE I+ L+E N +L+E K+ QL+ Sbjct: 2034 LNDKIENLKDQTQRFQ-----VYFSEKEETIRN---LKETVYNQNLQLEEKGKKLNQLQN 2085 Query: 1181 LNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWK 1240 N L +EQ+ + K ++ N + + + + IS + E Sbjct: 2086 DNEVLRKKYKDQEEQMMKNDIKFQRQNNRMEQIQKLIKDY-PKISKEIGDTIKNTEEFCL 2144 Query: 1241 QHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTM-EQVTSLQNKL 1299 + L F K L+ ++ E+ EQ + ++ Q++ + M Q ++ N+ Sbjct: 2145 EKLRFLTQLFMKKIQTLQEKIEESETANEQEIQKLKKQLQQQQQQYDEMFSQTLTINNEN 2204 Query: 1300 QDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSY 1359 D H +++ + + I++ + + E++ +K F Q + Sbjct: 2205 PDMMTHFKDVLK---NAISERDQFQQELKQKKEQFDNASVENNYLKLQVQNLKDQLEQKW 2261 Query: 1360 KQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVL--------ELTHQLEL 1411 + QS+ + +N +++K V K +L QL+ Sbjct: 2262 NESANQSLDLSSIDNQEIRKFEHSSINNATIIDPTVQSGHTKSSLQIKEFQNQLAQQLQQ 2321 Query: 1412 KDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENAN 1471 ++ K ++ + + E E + L++Y++ E + S+L ++ + N Sbjct: 2322 QNENNNTKFYDLQLEIDSYKQEIEKYKMNLIDYQQE-EQKMVKMISDLKRENYQLSQTIN 2380 Query: 1472 HYETMQKESEIERV 1485 +T + +I+++ Sbjct: 2381 QTDTKSLKQQIKQL 2394 Score = 138 bits (333), Expect = 2e-30 Identities = 299/1520 (19%), Positives = 634/1520 (41%), Gaps = 145/1520 (9%) Query: 164 KMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQE 223 K KI+ ++ +++Q+ + Q++E N ++K Q K Sbjct: 40 KPKILSSSQIEMQQLAEKNKQLVEDLNFLNLSFKELKLGTDEL------NSKNQSLKKHI 93 Query: 224 NFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELE---Q 280 + + K+++ LK K +EE NK E + + ++ K Q LE + Sbjct: 94 KELLQTLKHKEDE---LKKAREKQKNGEQIEE-NKTQEKSVIDYAIYMEKQFQTLEDKVK 149 Query: 281 XXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIE-LLEHLNCQIR 339 LAK+ E + I+EK +++ E+ +I+ L Q++ Sbjct: 150 KYKKLLEKNGYDDQLAKKVEEQKKSIQQLIQEKETIK-REKEEIQNQIQNQRSDLEPQLK 208 Query: 340 QTNKELENKLATMGTESKAVSSPSKK-GSPLISRKSGRNTASKMKSPWSQLSSETLNQ-- 396 N++L+N E + +S +K + LI + ++ KS L S Q Sbjct: 209 ILNEQLQNSEQLHIQEIQLKNSMIEKLNNQLIKLMDNQKQLNESKSHNQILQSRITEQER 268 Query: 397 ---DTDKKINKNEIAKLEMV--IQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQ 451 D D++ LE IQ LNK++ + +++++ K+ Q Sbjct: 269 KYKDLDEQAKHVNGTALEYSKQIQQLNKEIQTYKQQLAQQEEQCNRIVQQKQ-KEINQVQ 327 Query: 452 LQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQE---LNDEIKDVNVKDLIEKLKSA 508 QLE Q+H+E +L N + ++ + L+ + L DE + K + LK+ Sbjct: 328 SQLE-QKHLE-ETLKKQQQNEQQYLQVIEQFNSLQNKIALLEDENSSLKQKSF-KTLKNV 384 Query: 509 EEQITQLNDEID----AANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVR----- 559 +++ ++ E+ + ++ ++ ++ + Q+++ I K + +EIV+ Sbjct: 385 VQELKRMKLELQNLKMMGHYDISQLNGLEQILMDQLEQAISQPHKNQEYMQEIVQEMSQE 444 Query: 560 --LTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYK-----KMIEMENLAETR 612 LTE +Q +L + K + L D + +I+ + K + + + Sbjct: 445 QSLTERTQVQNQLQLQLIKHKQVFKFILEDVCNSEVIKQQILNTLGQFKQFLLNIIQQQY 504 Query: 613 LKAISLLESQKFD-------LVQELHILQQKYDEVEDKLADIS-QLQSDQVCSEIKSVHL 664 LK++ L+ +QK D L+QEL+ + Q+ E++ + ++ Q+QS Q + + +L Sbjct: 505 LKSLDLMNNQKQDYSSQIDSLIQELNNVNQQLFEMQKQNTNLQEQIQSKQDEHQYEMQNL 564 Query: 665 EEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKL------QNYIQENM 718 + QID L++ +E +NL+ D + I +N + +L Q Q+ + Sbjct: 565 QGQIDNLNSILEETN---QNLEKDNQN-QALIDHYQNQISQLETQLAQSQQQQKTQQQTL 620 Query: 719 DLTDKLEKMSAEKISELLAKINH--------EEQSKIQTQFGI--DAKIQERDLYIENIE 768 + + + +++E K+N EE K+Q Q K + L + ++ Sbjct: 621 NTAIEQSNVKDAELNETKQKLNSLNTLLKQKEEDLKMQKQLAQTKSTKYDQEKLLTQKLQ 680 Query: 769 SELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELV---N 825 E+ K++ + + + +D + +L + Q+ ++ ++ + EL + Sbjct: 681 QEIEALKTQNKQFQLDLNRQKDLNKQQQTDLGKLKADNQQLKQQSEQFLQTQQELTKIKS 740 Query: 826 RLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEE---NQNLQISLSDMQQHYNALVEK 882 + + +++Q E++ L N L EE N L+ L ++Q + E+ Sbjct: 741 EFSKTLQEKNTLQEQFDEVKKSQALLTTLNDELQEEQQINDKLKQQLLELQLEFENSKEQ 800 Query: 883 ANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRD 942 ++ + + QL+DL ++ + E+Q L Q + ++L Q++S + Sbjct: 801 MENYS---QDNERLKQQLKDLNNDYELTLQENQMLQEQIISKDQNL-----IQLQS--QQ 850 Query: 943 KKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPD 1002 ++ +N ++IE Q + + ++ N+ E+L + +L K++LE + + + QT + Sbjct: 851 QEQINLFCSQSIE---QSDLKNKDLANSNESLQSQIYDL-KLSLEQAQETIGQNQTSIQE 906 Query: 1003 YTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEE 1062 + ++ N+ LK + +E+ NQ+I + + MS+ + E + T++LE + Sbjct: 907 LQADSL-KLKDENSTLKNQIQELSIKNQQIQESLETQMSISQNQEKLIQNQTSQLEQEQV 965 Query: 1063 EMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMS 1122 QR QL + + E L+ + +D ++ E + ++ ++E + + E S Sbjct: 966 NNQRQGIQLTNLNKKFEALEQQLESKDQELNEYIQQTNYLKIKNEQSEQQLFKQSQELQS 1025 Query: 1123 DDANNVDXXXXXXXXXXXXLKVQEEEEFIQER-SVLQEQSAKLNTELQECYTKIIQLE-- 1179 + + N ++E E+ +QE +Q Q +++ +L+E + L+ Sbjct: 1026 NKSQNQSSNESIVQLNELVNHLREGEKQLQESVKEIQNQKSQIQKQLEEKEQLLQNLQQE 1085 Query: 1180 --TLNTELTGHDVVNQEQINQLKSKLEQLNTE-NDNLLSTVAELRSSI---SSAVDQRGF 1233 LN L NQ Q Q++S +L + N+ L +L+ +I ++ + Q Sbjct: 1086 NKNLNAALLAEKSENQTQSEQIRSLQNELIQKINETTLENEKQLQLNIQQQNNKIQQYEL 1145 Query: 1234 EIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVT 1293 +I++ +KQ ++ Q+ E ++ + ++ Q + +Q + Q + ++I +Q Sbjct: 1146 QISK-YKQQNENLNSNLQEAEKHKQLDKNQI-AELNQNIQELQRNLQSQLSQIEESKQ-- 1201 Query: 1294 SLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLR 1353 QN K++ ++ L K + +QIE + +++ EK + Sbjct: 1202 --QNN--QKDQQIQQLLLKIDEQKSQIESISLQLQSEKKNLLEDNDVLKNANQQLQGLEQ 1257 Query: 1354 TENQSYKQMQEQSILNINE----ENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQL 1409 + Q+++ I+E EN LK + + + + +Q Sbjct: 1258 QQQTIIAQLKQDYEKKISEQKDLENQILKLEQNYQNESSNRQTIQNSLNQQREENEQNQQ 1317 Query: 1410 ELKDSEIY-QKTHEYTITLTQRN----DEFENVRQQLVEYEKRIEDLTYEKESELAILRL 1464 ELK+ I Q E TL Q++ +E N++ QL + + +++ + I Sbjct: 1318 ELKNRLIQNQSLIEEVDTLKQQHLLNQEENLNLQTQLKDLTQEEQNIRANARQQEQIQNQ 1377 Query: 1465 KMHENANH-------YETMQKES---EIERVKLIEELNVKITE----SVSLNKQVAELNK 1510 K+ E N E +QK+ + E+ K+ EEL+ K + S + Q + + Sbjct: 1378 KIQELINENREAQNLVEILQKQIVQIQYEKEKIEEELSEKNLQLDNYSNEIEDQKTQFLQ 1437 Query: 1511 ALE-----EEVAKTNEMQTALE--NQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASD 1563 +E +++ + + QT E N + +I LN + LQN ++ SS IQK + + Sbjct: 1438 KIEILQQNQQILEIQKKQTDNEILNYQNQIEKLNQDNLQLQNELKVLSSNIQKDIDSMKE 1497 Query: 1564 TKQGRDE---QLDNTMNKEL 1580 + + QL N KEL Sbjct: 1498 KQIAEKDAQLQLKNQEIKEL 1517 Score = 133 bits (321), Expect = 4e-29 Identities = 213/1157 (18%), Positives = 496/1157 (42%), Gaps = 78/1157 (6%) Query: 480 KVQEQLK--QELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNH---- 533 KV+EQ K Q+L E K+ ++ E + Q + L ++ N+ + + H Sbjct: 167 KVEEQKKSIQQLIQE-KETIKREKEEIQNQIQNQRSDLEPQLKILNEQLQNSEQLHIQEI 225 Query: 534 KLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRM 593 +LK ++K + K+ D+ K++ L ++ E E + +L + +G Sbjct: 226 QLKNSMIEKLNNQLIKLMDNQKQLNESKSHNQILQSRITEQERKYKDLD-EQAKHVNGTA 284 Query: 594 IESDVYKKMIEMENLA-ETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLAD--ISQL 650 +E Y K I+ N +T + ++ E Q +VQ+ Q++ ++V+ +L + + Sbjct: 285 LE---YSKQIQQLNKEIQTYKQQLAQQEEQCNRIVQQK---QKEINQVQSQLEQKHLEET 338 Query: 651 QSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKL 710 Q +E + + + EQ ++L K L EN L K++ + T+K++ + + + +L Sbjct: 339 LKKQQQNEQQYLQVIEQFNSLQ--NKIALLEDENSSL-KQKSFKTLKNVVQELKRMKLEL 395 Query: 711 QNY-IQENMDLT--DKLEKMSAEKISELLAKI--NHEEQSKIQTQFGIDAKIQERDLYIE 765 QN + + D++ + LE++ +++ + +++ N E +I + + + ER Sbjct: 396 QNLKMMGHYDISQLNGLEQILMDQLEQAISQPHKNQEYMQEIVQEMSQEQSLTERTQVQN 455 Query: 766 NIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVN 825 ++ +L K+K + E + E + + + LG + Q + ++ +L+N Sbjct: 456 QLQLQLIKHKQVFKFILEDVCNSEVIKQQI---LNTLGQFKQFLLNIIQQQYLKSLDLMN 512 Query: 826 RLAVLMDHDRVVEKQLLEIEHENK---ELQKKNQILLEENQNLQISLSDMQQHYNALVEK 882 D+ ++ + E+ + N+ E+QK+N L E+ Q+ Q Q+ ++ Sbjct: 513 NQK--QDYSSQIDSLIQELNNVNQQLFEMQKQNTNLQEQIQSKQDEHQYEMQNLQGQIDN 570 Query: 883 ANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIE-SAIR 941 N +++ + Q + L + + + +T + Q +++ + + NT IE S ++ Sbjct: 571 LNSILEETNQNLEKDNQNQALIDHYQNQISQLETQLAQSQQQQKTQQQTLNTAIEQSNVK 630 Query: 942 DKKVLNEKYEKNIEYVTQLEAQLQEYK--NNIENLNMNVEELNKMNLELIDKHVQKQQTQ 999 D + LNE +K T L+ + ++ K + + K+ + + + ++ +TQ Sbjct: 631 DAE-LNETKQKLNSLNTLLKQKEEDLKMQKQLAQTKSTKYDQEKLLTQKLQQEIEALKTQ 689 Query: 1000 SPDYTEQYINEINKLNALLKQKDEEIIAL---NQKINNAQVSYMSMVSDYESKLAQFTTK 1056 + +Q+ ++N+ L KQ+ ++ L NQ++ ++ + ++F+ Sbjct: 690 N----KQFQLDLNRQKDLNKQQQTDLGKLKADNQQLKQQSEQFLQTQQELTKIKSEFSKT 745 Query: 1057 LE---NMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMI 1113 L+ ++E+ V K N+ELQ + D ++L E +L FE + + E Sbjct: 746 LQEKNTLQEQFDEVKKSQALLTTLNDELQEEQQINDKLKQQLLELQLEFENSKEQMENYS 805 Query: 1114 -ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECY 1172 + ++ D NN + +++ IQ +S QEQ +N C Sbjct: 806 QDNERLKQQLKDLNNDYELTLQENQMLQEQIISKDQNLIQLQSQQQEQ---INL---FCS 859 Query: 1173 TKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRG 1232 I Q + N +L + Q QI LK LEQ +++ EL++ D+ Sbjct: 860 QSIEQSDLKNKDLANSNESLQSQIYDLKLSLEQAQETIGQNQTSIQELQADSLKLKDEN- 918 Query: 1233 FEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQV 1292 K + + Q+ + L Q+S +++ + + + QE+ N Q+ Sbjct: 919 ----STLKNQIQELSIKNQQIQESLETQMSISQNQEKLIQNQTSQLEQEQVNNQRQGIQL 974 Query: 1293 TSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDL 1352 T+L K + E+ L + ++ + I Q L+ + E + Sbjct: 975 TNLNKKFEALEQQLESKDQELNEYIQQTNYLKIKNEQSEQQLFKQSQELQSNKSQN---- 1030 Query: 1353 RTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQ-LEL 1411 ++ N+S Q+ E + ++ E QL++S ++ + E + L + L Sbjct: 1031 QSSNESIVQLNE-LVNHLREGEKQLQESVKEIQNQKSQIQKQLEEKEQLLQNLQQENKNL 1089 Query: 1412 KDSEIYQKTHEYTIT---LTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHE 1468 + + +K+ T + + +N+ + + + +E EK+++ ++ +++ L++ + Sbjct: 1090 NAALLAEKSENQTQSEQIRSLQNELIQKINETTLENEKQLQLNIQQQNNKIQQYELQISK 1149 Query: 1469 NANHYETMQKE-SEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALE 1527 E + E E+ K +++ + LN+ + EL + L+ ++++ E + Sbjct: 1150 YKQQNENLNSNLQEAEKHKQLDK-----NQIAELNQNIQELQRNLQSQLSQIEESKQQNN 1204 Query: 1528 NQEIEIVTLNDEITNLQNMVRASSSKIQ---KHVSFASDTKQGRDEQLDNTMNKELLDAV 1584 ++ +I L +I ++ + + S ++Q K++ +D + ++QL + ++ + Sbjct: 1205 QKDQQIQQLLLKIDEQKSQIESISLQLQSEKKNLLEDNDVLKNANQQLQG-LEQQQQTII 1263 Query: 1585 PRAELDLAMYMLHQRDV 1601 + + D + Q+D+ Sbjct: 1264 AQLKQDYEKKISEQKDL 1280 Score = 132 bits (318), Expect = 1e-28 Identities = 231/1158 (19%), Positives = 479/1158 (41%), Gaps = 108/1158 (9%) Query: 502 IEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVR-- 559 + KL + E + N E+ + ++ K + K K + + ++++ NK++V Sbjct: 6 LHKLNNLLETVNLRNQELLSQLQSDYKSRETSPPKPKILSSSQIEMQQLAEKNKQLVEDL 65 Query: 560 --LTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAIS 617 L L EL + +L+ H+ + + D KK E + E I Sbjct: 66 NFLNLSFKELKLGTDELNSKNQSLKKHIKELLQTLKHKEDELKKAREKQKNGEQ----IE 121 Query: 618 LLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKE 677 ++Q+ ++ +++++ +EDK+ +L + + +EEQ S ++ Sbjct: 122 ENKTQEKSVIDYAIYMEKQFQTLEDKVKKYKKLLEKNGYDDQLAKKVEEQ----KKSIQQ 177 Query: 678 LALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLA 737 L E +K +KE++ I +N + D+ +L+ + E + +++L + + ++ Sbjct: 178 LIQEKETIKREKEEIQNQI---QNQRSDLEPQLK-ILNEQLQNSEQLHIQEIQLKNSMIE 233 Query: 738 KINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLER 797 K+N++ + Q ++ + I + KYK L+E + + Sbjct: 234 KLNNQLIKLMDNQKQLNESKSHNQILQSRITEQERKYKD----LDEQAKHVNGTALEYSK 289 Query: 798 KADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQI 857 + QL +Q Y + Q++E NR+ + + LE +H + L+K+ Q Sbjct: 290 QIQQLNKEIQ----TYKQQLAQQEEQCNRIVQQKQKEINQVQSQLEQKHLEETLKKQQQ- 344 Query: 858 LLEENQNLQISLSDMQQHYNALVEK-ANRTDLAESESTKYQTQLRDLESNLKRITHEHQT 916 E Q LQ+ + +N+L K A D S K L+++ LKR+ E Q Sbjct: 345 --NEQQYLQVI-----EQFNSLQNKIALLEDENSSLKQKSFKTLKNVVQELKRMKLELQN 397 Query: 917 LIVQKKKEIED---LEIEFNTQIESAI----RDKKVLNE-----KYEKNIEYVTQLEAQL 964 L + +I LE Q+E AI ++++ + E E+++ TQ++ QL Sbjct: 398 LKMMGHYDISQLNGLEQILMDQLEQAISQPHKNQEYMQEIVQEMSQEQSLTERTQVQNQL 457 Query: 965 Q----EYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQ 1020 Q ++K + + +V + ++++ Q +Q +QY+ ++ +N + Sbjct: 458 QLQLIKHKQVFKFILEDVCNSEVIKQQILNTLGQFKQFLLNIIQQQYLKSLDLMNNQKQD 517 Query: 1021 KDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQL--LDS--KQ 1076 +I +L Q++NN M + Q +K + + EMQ + Q+ L+S ++ Sbjct: 518 YSSQIDSLIQELNNVNQQLFEMQKQNTNLQEQIQSKQDEHQYEMQNLQGQIDNLNSILEE 577 Query: 1077 HNEEL------QILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDX 1130 N+ L Q L+ +QI +L ET+L KT+ +++ IE + ++ Sbjct: 578 TNQNLEKDNQNQALIDHYQNQISQL-ETQLAQSQQQQKTQQQTLNTAIEQSNVKDAELNE 636 Query: 1131 XXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTE---LQECYTKIIQLETLN----T 1183 LK Q+EE+ ++ + Q +S K + E Q+ +I L+T N Sbjct: 637 TKQKLNSLNTLLK-QKEEDLKMQKQLAQTKSTKYDQEKLLTQKLQQEIEALKTQNKQFQL 695 Query: 1184 ELTGHDVVNQEQ---INQLKSKLEQLNTENDNLLSTVAEL---RSSISSAVDQRGF---E 1234 +L +N++Q + +LK+ +QL +++ L T EL +S S + ++ + Sbjct: 696 DLNRQKDLNKQQQTDLGKLKADNQQLKQQSEQFLQTQQELTKIKSEFSKTLQEKNTLQEQ 755 Query: 1235 IAELWKQH-----LAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTM 1289 E+ K L + Q+ +L+ QL + ++E + +++ +Q+ Sbjct: 756 FDEVKKSQALLTTLNDELQEEQQINDKLKQQLLELQLEFENSKEQMENYSQDNER---LK 812 Query: 1290 EQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXX 1349 +Q+ L N + + + LQE+ + L+S+ +++ F Sbjct: 813 QQLKDLNNDYELTLQENQMLQEQIISKDQNLIQLQSQQQEQINLF---CSQSIEQSDLKN 869 Query: 1350 XDLRTENQSYKQM---------QEQSILNINEENAQ-LKKSSXXXXXXXXXXXXRVNDAE 1399 DL N+S + Q Q + N+ + Q L+ S ++ + Sbjct: 870 KDLANSNESLQSQIYDLKLSLEQAQETIGQNQTSIQELQADSLKLKDENSTLKNQIQELS 929 Query: 1400 AKVLELTHQLELKDSEIYQKTHEYTITLTQR--NDEFENVRQ--QLVEYEKRIEDLTYEK 1455 K ++ LE + S I Q + T + ++ N RQ QL K+ E L + Sbjct: 930 IKNQQIQESLETQMS-ISQNQEKLIQNQTSQLEQEQVNNQRQGIQLTNLNKKFEALEQQL 988 Query: 1456 ESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKA---L 1512 ES+ L + + N+ + ++SE + K +EL +++ S N+ + +LN+ L Sbjct: 989 ESKDQELN-EYIQQTNYLKIKNEQSEQQLFKQSQELQSNKSQNQSSNESIVQLNELVNHL 1047 Query: 1513 EEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQL 1572 E + E ++NQ+ +I +E L ++ + + + Q + EQ+ Sbjct: 1048 REGEKQLQESVKEIQNQKSQIQKQLEEKEQLLQNLQQENKNLNAALLAEKSENQTQSEQI 1107 Query: 1573 DNTMNKELLDAVPRAELD 1590 + N EL+ + L+ Sbjct: 1108 RSLQN-ELIQKINETTLE 1124 Score = 124 bits (298), Expect = 3e-26 Identities = 217/1114 (19%), Positives = 471/1114 (42%), Gaps = 85/1114 (7%) Query: 237 QRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLA 296 Q LKD+ ++ I + + ++ + + + ++ AQ L + Sbjct: 1351 QTQLKDLTQEEQNIRANARQQEQIQNQKIQELINENREAQNLVEILQKQIVQIQYE---- 1406 Query: 297 KQSIEPSCEEKTEIEEKGSLEIANM-TELTKKIELLEH----LNCQIRQTNKEL---ENK 348 K+ IE EK + S EI + T+ +KIE+L+ L Q +QT+ E+ +N+ Sbjct: 1407 KEKIEEELSEKNLQLDNYSNEIEDQKTQFLQKIEILQQNQQILEIQKKQTDNEILNYQNQ 1466 Query: 349 LATMGTESKAVSSPSKKGSPLISRK--SGRNTASKMKSPWSQLSSETLNQDTDKKINKNE 406 + + ++ + + K S I + S + K QL ++ + + +K I +E Sbjct: 1467 IEKLNQDNLQLQNELKVLSSNIQKDIDSMKEKQIAEKDAQLQLKNQEIKELKEKNIQLDE 1526 Query: 407 ----IAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEG 462 I +L+ I+ N+ + + + E + K+ Q L+ + +E Sbjct: 1527 KMKLIGELQNQIRQTNEKFQENQQKLQELEITINQLNQGIQTKEQE-CQESLKKSRELED 1585 Query: 463 PSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAA 522 L+ N + ++ + +QE++ Q K+ N + + ++LK +++++++ +E Sbjct: 1586 RLLVAQQENKKLISSVENLQEEISQ------KNQNEQTIQDELKQFQQEVSKIKEEKILQ 1639 Query: 523 NKNMIKVKSNHKL---KLKQMQKTIDNFSKVSDSNKEIVR-LTEELHHLSQKVAELEEEK 578 +I + L K+ Q+ D + K++++ L ++L Q+ + E Sbjct: 1640 ESEIISKNTQLNLQEQKISQLNDEKDYLKTQMNEGKDMLKDLQQKLELQQQRQQKYEALV 1699 Query: 579 GNLQLHLVDYDSGRMIE--SDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQK 636 N +L + E S +++EN A+ +L +I L+E K Q Q Sbjct: 1700 KNEELKYLQKIENLETELSSQQVNSKLKIEN-AKRKLHSI-LIEFGKCKRQQ-----QHS 1752 Query: 637 YDEVEDKLADISQLQSDQVCSEIKSVH-LEEQIDALSASKKELALVIENLKLDKEQLYGT 695 + ++D+L ++ + +K + + QI L + +EL ++ Q+Y Sbjct: 1753 TNFIKDQLVKFNKTYQTILVKLVKKLSVINSQIAQLKLNHQELDDMLRVQVKINPQIYKH 1812 Query: 696 IKDLENDKEDIMNKLQNYIQ------ENMDLTDKLEKMSAEKISELLAKINHEEQS---K 746 + L+ +E ++ + IQ ENM D+ K + +S + + ++ Q K Sbjct: 1813 LNQLQQQQESVVKSFKEKIQQLMSQQENMLFADENRKQEIQSLSTDRSDLKNQLQETNQK 1872 Query: 747 IQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRY---SLERKADQLG 803 +Q Q I+ +++E I+ +ES+ Y+ +I +I ++ +L+ + QL Sbjct: 1873 LQQQQQINLELKEE---IQRLESQNLLYQGQIQEKNSAIDQQNEKCKLIPNLKNEIQQLE 1929 Query: 804 SYLQEKQKAYSE----YTIQEDELVNRLAVLMDHDR-VVEKQLLEIEHENKELQKKNQIL 858 Q +Q +E + + D ++ L + +R ++ Q ++ + +LQK Q L Sbjct: 1930 QQRQRQQTMINEIQASFQVTIDHQQEQIQSLKEQNRDLLSGQEIKTQDIYLKLQKLEQQL 1989 Query: 859 LEENQ-NLQI--SLSDMQQHYNALVEKANRTDLAESES-TKYQTQLRDLESNLKRITHEH 914 ++E Q + QI LS + L + A R +L+E ++ T L D NLK T Sbjct: 1990 IKEKQFSQQIFDKLSSKDEEIQQL-QLAQRKNLSEIDNLTNINEDLNDKIENLKDQTQRF 2048 Query: 915 QTLIVQKKKEIEDL-EIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNI-- 971 Q +K++ I +L E +N ++ + KK+ + + + + + Q KN+I Sbjct: 2049 QVYFSEKEETIRNLKETVYNQNLQLEEKGKKLNQLQNDNEVLRKKYKDQEEQMMKNDIKF 2108 Query: 972 ENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQK 1031 + N +E++ K+ + + K+ + TE++ E KL L + ++I L +K Sbjct: 2109 QRQNNRMEQIQKLIKDY--PKISKEIGDTIKNTEEFCLE--KLRFLTQLFMKKIQTLQEK 2164 Query: 1032 INNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEE-LQILVREQDD 1090 I ++ + + + +L Q + + M + ++ + D H ++ L+ + E+D Sbjct: 2165 IEESETANEQEIQKLKKQLQQQQQQYDEMFSQTLTINNENPDMMTHFKDVLKNAISERDQ 2224 Query: 1091 QIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEF 1150 +ELK+ K F+ E + ++ + D + QE +F Sbjct: 2225 FQQELKQKKEQFDN--ASVENNYLKLQVQNLKDQLEQKWNESANQSLDLSSIDNQEIRKF 2282 Query: 1151 IQERSVLQEQSAKLNTELQECYTKI-IQLETLNTELTGHDVVNQEQINQLKSKLEQLNTE 1209 E S + + ++ +Q +TK +Q++ +L Q+Q +K L E Sbjct: 2283 --EHSSINNATI-IDPTVQSGHTKSSLQIKEFQNQLAQQ---LQQQNENNNTKFYDLQLE 2336 Query: 1210 NDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYE 1269 D+ + + + ++ +D + E ++ K + ++Q ++ + + + + + Sbjct: 2337 IDSYKQEIEKYKMNL---IDYQQEE-QKMVKMISDLKRENYQLSQTINQTDTKSLKQQIK 2392 Query: 1270 QLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKE 1303 QLL S S Q + + Q+ S +L D+E Sbjct: 2393 QLLQSFLVSLQNQAQETEDYFQILSKMLELTDQE 2426 >UniRef50_A0DXX1 Cluster: Chromosome undetermined scaffold_69, whole genome shotgun sequence; n=2; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_69, whole genome shotgun sequence - Paramecium tetraurelia Length = 3066 Score = 165 bits (402), Expect = 7e-39 Identities = 275/1450 (18%), Positives = 624/1450 (43%), Gaps = 128/1450 (8%) Query: 149 NTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXX 208 N K+ + L +++ + + LQ+K+ EK+++I+ K++ Sbjct: 1416 NEKKQLQDQLHQKNLQIAALNDELSKLQQKVFEKEKVIDEKDR--EFRNSQLIKTYQDNC 1473 Query: 209 XXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEIS 268 ++ + +++E +E EKQ+ +K++E + SS+ E+ + S Sbjct: 1474 NKADELISKNNQIEETLNNLEVRLA-EKQQRVKELELQIGADSSISNIQDPRESGMIK-S 1531 Query: 269 LEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIAN-MTELTKK 327 + + Q L+Q L K IE E E +K +LE+ N + +L K+ Sbjct: 1532 YDQEQDTQ-LQQQEQVLQGYSMNIDQL-KNKIEQLNSELAE-RDKTNLELRNQVADLKKQ 1588 Query: 328 I---ELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKS 384 I +L + I++ NK+L+++++ + ++ + + K R M+ Sbjct: 1589 IHGYQLAQQDVKVIKKQNKQLQDEISALVQDNLNYEDLIRDSEFKLQEKKSRVKELDMEI 1648 Query: 385 PWSQLSSETLNQDTDKKINKNEIAKLEMVIQ---SLNKDLVDKEYVISEKDTXXXXXXXX 441 +++ + Q + ++ + +I + + +I+ L++ L + E I +K Sbjct: 1649 KNAEIQIQVEKQMKENQLLQQKIQQTDELIKKNLELDEALTNLELRILDKQQQLSQKEAR 1708 Query: 442 XXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDL 501 +++ I Q + Q ++ T T + A+ Q L QE N+ N+ +L Sbjct: 1709 LSNQNSRILQQPMYIYQEDSDDKASNIRTET---SPRAQNQHPLIQEHNN-----NLSEL 1760 Query: 502 IEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLT 561 + +EQ+ QL+ + D+ ++ K +L++ +++ ++ N+ + L Sbjct: 1761 TSSINQMQEQVRQLSLD-DSELDFYLQQKKEKQLEIDSLKQ------QLFQQNEVMQDLK 1813 Query: 562 EELHHLSQKVAELEEEKGNLQ--LHLVDYDSGRMIESDVYKK-MIEMENLAETRLKAISL 618 +E Q++ +L++E N + + +MIE ++ KK + + + + I Sbjct: 1814 QEQIEKQQQIDQLKKENSNFDELVEELQQSQKQMIEQEIQKKESNQPQEIGGSEQSEIIK 1873 Query: 619 LESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKEL 678 +S+ +L ++LH L+Q ++++++A+ D + ++++V +++ D +K+ Sbjct: 1874 TKSENLELSKKLHDLKQSQKQLKNQIANY-----DYLILDLETVVADKKNDIQRLNKENQ 1928 Query: 679 ALVIENLK-------LDKEQ--LYGTIKDLENDKEDIMNKLQNYIQENM-DLTDKLEKMS 728 + +N K L KEQ L +K LE ++ + + + +QE++ L +KL+++ Sbjct: 1929 SYQQQNRKQKGRRDLLHKEQNNLQYQLKLLEPQLQE-LQQTEKQLQESVTQLEEKLKQLD 1987 Query: 729 AEKISELLAKINHEEQ--SKIQTQFG-IDAKIQERDLYIENIESELSKYKSRICRLEESI 785 EK +L +IN ++Q S ++ Q I+ +I ++ + ++SEL++ + +E+ + Sbjct: 1988 -EKQKQLENQINQKQQITSALELQLSTINQEILQQQDKKQQLDSELNQLRDENQGIEQEV 2046 Query: 786 AVMED---RRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLL 842 + + +L + D L + E ++ Y ++ ++ +L+ + K++ Sbjct: 2047 KIYRNLSLEDITLNEQIDALTKQIHEDKQTYETLQDEQKATQEQINLLLPQN----KEID 2102 Query: 843 EIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRD 902 E++ E +LQ + E NLQ+ L + N + ++ + T+ E+ L + Sbjct: 2103 ELK-ETAKLQYAQNV--EALNNLQLELQQKIEQKNKVFQEVSDTEKYLEENNHVLQDLNE 2159 Query: 903 LESNLKRITHEHQTLI----VQKKKEIEDLEIE------FNTQIESAIRDKKVLNEKYEK 952 ++NL+ + + L+ + K+ E LE E N ++E ++ K+V ++ K Sbjct: 2160 RKANLEDQIKKEEVLVNAVSAKSKRLDETLEAEKQNYNVLNAELEDLLKRKQVQEQELAK 2219 Query: 953 NIEYVTQLEA---QLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYIN 1009 E + +++A QL + + +NL +E+ NK ++E+ K + P+ EQ + Sbjct: 2220 AKEEIQKMQADQEQLLQQQQQFKNLKEQIEQYNK-DIEINLKII-------PEREEQLV- 2270 Query: 1010 EINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSK 1069 +L ++++KDE + A +++ + D E K +LE+ ++ + + Sbjct: 2271 ---QLKCIIEKKDEVLSATQAEVDKLNKQIDEIQQDKEQK----EKELEDQSNLVKSIEE 2323 Query: 1070 QLLDSKQHNEELQ-----ILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDD 1124 Q++D Q ++L+ I +++ + ++ E E + + + E + ++ + DD Sbjct: 2324 QIIDKYQREKDLKDQLDSIQLKDLEAELNEKMEQSMAQQEMLDSIEQ--LKQQVQQLRDD 2381 Query: 1125 ANNVDXXXXXXXXXXXXLK---VQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETL 1181 + K Q+++E I+ L SA++ + K QL+ L Sbjct: 2382 ETQLKQQIQGQESLNNSKKQELEQKQQEKIELEQDLHSASAQMEEMKFQLEEKNEQLDKL 2441 Query: 1182 NTEL--TGHDVVNQEQINQLKSK-LEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAEL 1238 N + D E + QLK K L+QL + +NL+ + + + + A Q + + Sbjct: 2442 NDQFKKVDEDSKMMEAVLQLKEKELKQLQKKKENLIEELERINNDVVEAQKQL---VTQR 2498 Query: 1239 WKQHL--AQREADFQKTEHELRVQLSAFESKYEQLLDSVQS----STQEETNKIVTMEQV 1292 KQ A+ + + E +++ ++++ S+ L D +Q S + K ++V Sbjct: 2499 KKQRSLGAEPQQQDENMEEDIQDKITSLNSRNNNLKDDLQKLVEMSPEPTERKPEEQQEV 2558 Query: 1293 TSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEI----EDEKVAFXXXXXXXXXXXXXX 1348 +Q + +Q+ D +IEIL I + ++ Sbjct: 2559 KDAPAPVQVSQFAPDRVQQTLQDRDKKIEILEMTISTLQQQQQERMSMIPSMFQSKLSVQ 2618 Query: 1349 XXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQ 1408 ++ ++Q++ +E L+ ++ D K L + Sbjct: 2619 PSFFMDDDPLLLELQDK-FTKESELLKDLQNKIKQTAESHYALSLQLKDWAEKENRLAKE 2677 Query: 1409 LELKDSEIYQKTHEYTITLTQRND---EFENVRQQLVEYEKRIEDLTYEKESELAILRLK 1465 L+ + + Q E +++D E NV Q++ E +D YE+E A + K Sbjct: 2678 LDTRRQSVEQIEFELQAVFAKQSDLESEKVNVLQRIYSLEVETQDF-YEQE---ANTKNK 2733 Query: 1466 MHENANHYETMQK---ESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEM 1522 + E ++ +T+ K ES+ + ++L + + E L +QV L E + ++ Sbjct: 2734 LKEKKDYLQTLYKNLIESDQKLLQLRNRMALYSQEGRQLAEQVENLENEKENKQQHLQDI 2793 Query: 1523 QTALENQEIE 1532 Q LE+ E+E Sbjct: 2794 QADLEHVEME 2803 Score = 139 bits (337), Expect = 5e-31 Identities = 292/1461 (19%), Positives = 619/1461 (42%), Gaps = 141/1461 (9%) Query: 216 QQMTKMQENFIAMEAEWKDEKQRL--LKDIESKDVRISSLEEANKLL--EAARFEISLEH 271 +QM ++E E E K K+++ +++ +++ E N L + R E L++ Sbjct: 1078 EQMEILKEQLKEKEDELKAYKEQIPSIQEYQNQQFLHQQEELVNTELRKDVQRLEDQLDN 1137 Query: 272 S-KLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIEL 330 KL +EL+Q K SI S ++I + + E +K + Sbjct: 1138 QLKLNKELQQRMDNQHESAALLSQKIKLSIHDSNSSSSQIIDNRQ----RLVEKQQKADE 1193 Query: 331 LEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGS-PLISRKSGRNTASKMKSPWSQL 389 L + + ++LE KL + + K+G+ P + +S N K++ P +Q+ Sbjct: 1194 LVREHLSLDDLIEDLEKKLVEKNDYKDQLLNQLKEGTKPAV--QSEANEQPKVEQP-NQV 1250 Query: 390 SSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLI 449 ++ NQ+ + + EI+ ++ VI + N+D + + K+ Sbjct: 1251 FAKQQNQEQFVEPIQ-EISDVQQVISN-NEDQISIPLQAGQILQQLEGDSQKQDIKEPNP 1308 Query: 450 AQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKV---------QEQLKQELNDEIKDVNVKD 500 +Q +L +Q H + N + ++ +V Q+ +E D + V D Sbjct: 1309 SQ-ELSNQLHPTKSQPVFAQINQDAEPKLQQVKSSQGFTSPQDLFNKEGIDGQRLQEVWD 1367 Query: 501 LIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRL 560 L++ A+ +I +L D + NK +++ + + Q+ + +VSDS E +L Sbjct: 1368 LLKNNNDADRRIQELRDALQRKNKRKEQLEGVYN----KDQELVSQ--RVSDSVNEKKQL 1421 Query: 561 TEELHHLSQKVAELEEEKGNLQLHL------VDYDSGRMIESDVYKKMIEMENLAETRLK 614 ++LH + ++A L +E LQ + +D S + K + N A+ + Sbjct: 1422 QDQLHQKNLQIAALNDELSKLQQKVFEKEKVIDEKDREFRNSQLIKTYQDNCNKADELIS 1481 Query: 615 AISLLESQKFDLVQELHILQQKYDEVEDKL---ADISQLQSDQVCSEIKSVHLEE--QID 669 + +E +L L QQ+ E+E ++ + IS +Q + IKS E+ Q+ Sbjct: 1482 KNNQIEETLNNLEVRLAEKQQRVKELELQIGADSSISNIQDPRESGMIKSYDQEQDTQLQ 1541 Query: 670 ALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMS- 728 + ++ I+ LK EQL + E DK ++ +L+N + DL ++ Sbjct: 1542 QQEQVLQGYSMNIDQLKNKIEQLNSELA--ERDKTNL--ELRNQVA---DLKKQIHGYQL 1594 Query: 729 AEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVM 788 A++ +++ K N + Q +I + + DL I + E +L + KSR+ L+ I Sbjct: 1595 AQQDVKVIKKQNKQLQDEISAL--VQDNLNYEDL-IRDSEFKLQEKKSRVKELDMEIKNA 1651 Query: 789 EDR-RYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAV-LMDHDRVVEKQLLEIEH 846 E + + + K +QL ++ + ++ DE + L + ++D + + ++ + + Sbjct: 1652 EIQIQVEKQMKENQLLQQKIQQTDELIKKNLELDEALTNLELRILDKQQQLSQKEARLSN 1711 Query: 847 ENKELQKKNQILLEENQ-----NLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLR 901 +N + ++ + +E+ N++ S Q+ + L+++ N SE T Q++ Sbjct: 1712 QNSRILQQPMYIYQEDSDDKASNIRTETSPRAQNQHPLIQEHNNN---LSELTSSINQMQ 1768 Query: 902 DLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLE 961 + L E + QKK++ ++E ++ + + +V+ + ++ IE Q++ Sbjct: 1769 EQVRQLSLDDSELDFYLQQKKEK----QLEIDSLKQQLFQQNEVMQDLKQEQIEKQQQID 1824 Query: 962 AQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDY---TEQY-INEINKLNAL 1017 QL++ +N + L VEEL + ++I++ +QK+++ P +EQ I + N Sbjct: 1825 -QLKKENSNFDEL---VEELQQSQKQMIEQEIQKKESNQPQEIGGSEQSEIIKTKSENLE 1880 Query: 1018 LKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQ------- 1070 L +K ++ +++ N +Y ++ D E+ +A ++ + +E Q +Q Sbjct: 1881 LSKKLHDLKQSQKQLKNQIANYDYLILDLETVVADKKNDIQRLNKENQSYQQQNRKQKGR 1940 Query: 1071 --LLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNV 1128 LL +Q+N + Q+ + E Q++EL++T+ + ++ + E + E N + Sbjct: 1941 RDLLHKEQNNLQYQLKLLEP--QLQELQQTEKQLQESVTQLEEKL-KQLDEKQKQLENQI 1997 Query: 1129 DXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGH 1188 + L +E +Q++ Q+ ++LN +L++ I Q + L+ Sbjct: 1998 NQKQQITSALELQLSTINQE-ILQQQDKKQQLDSELN-QLRDENQGIEQEVKIYRNLSLE 2055 Query: 1189 DVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGF--EIAELWKQHLAQR 1246 D+ EQI+ L ++ + + L + I+ + Q E+ E K AQ Sbjct: 2056 DITLNEQIDALTKQIHEDKQTYETLQDEQKATQEQINLLLPQNKEIDELKETAKLQYAQN 2115 Query: 1247 EADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVT--MEQVTSLQNKLQDKEE 1304 + EL+ ++ ++++ D+ EE N ++ E+ +L+++++ KEE Sbjct: 2116 VEALNNLQLELQQKIEQKNKVFQEVSDT--EKYLEENNHVLQDLNERKANLEDQIK-KEE 2172 Query: 1305 HLRNL---QEKYADVINQIE-----ILRSEIED---EKVAFXXXXXXXXXXXXXXXXD-- 1351 L N + K D + E +L +E+ED K D Sbjct: 2173 VLVNAVSAKSKRLDETLEAEKQNYNVLNAELEDLLKRKQVQEQELAKAKEEIQKMQADQE 2232 Query: 1352 -LRTENQSYKQMQEQ-----SILNIN--------EENAQLKKSSXXXXXXXXXXXXRVND 1397 L + Q +K ++EQ + IN E+ QLK V+ Sbjct: 2233 QLLQQQQQFKNLKEQIEQYNKDIEINLKIIPEREEQLVQLKCIIEKKDEVLSATQAEVDK 2292 Query: 1398 AEAKVLELTHQLELKDSEIYQKTH------EYTITLTQRN----DEFENVRQQLVEYE-- 1445 ++ E+ E K+ E+ +++ E I QR D+ ++++ + +E E Sbjct: 2293 LNKQIDEIQQDKEQKEKELEDQSNLVKSIEEQIIDKYQREKDLKDQLDSIQLKDLEAELN 2352 Query: 1446 KRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQV 1505 +++E ++E +I +LK + Q + +I+ + + N K E ++ Sbjct: 2353 EKMEQSMAQQEMLDSIEQLKQQVQQLRDDETQLKQQIQGQESLN--NSKKQELEQKQQEK 2410 Query: 1506 AELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNL---QNMVRASSSKIQKHVSFAS 1562 EL + L A+ EM+ LE + ++ LND+ + M+ A +K + Sbjct: 2411 IELEQDLHSASAQMEEMKFQLEEKNEQLDKLNDQFKKVDEDSKMMEAVLQLKEKELKQLQ 2470 Query: 1563 DTKQGRDEQLDNTMNKELLDA 1583 K+ E+L+ +N ++++A Sbjct: 2471 KKKENLIEELER-INNDVVEA 2490 Score = 133 bits (321), Expect = 4e-29 Identities = 252/1342 (18%), Positives = 565/1342 (42%), Gaps = 99/1342 (7%) Query: 215 KQQMTKMQENFIAMEAEWKDEKQRLLKDIESK-DVRISSLEEANKLLEAARFEISLEHSK 273 K+Q ++Q+ A+ + + + L++D E K + S ++E + ++ A +I +E Sbjct: 1603 KKQNKQLQDEISALVQDNLNYED-LIRDSEFKLQEKKSRVKELDMEIKNAEIQIQVEKQM 1661 Query: 274 LAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEH 333 +L Q L K+++E E T +E + + +L++K L + Sbjct: 1662 KENQLLQQKIQQTDE------LIKKNLELD-EALTNLELR---ILDKQQQLSQKEARLSN 1711 Query: 334 LNCQIRQT-----NKELENKLATMGTESKAVSSPSKKGSPLISRKSGR-----NTASKMK 383 N +I Q ++ ++K + + TE+ S ++ PLI + ++ ++M+ Sbjct: 1712 QNSRILQQPMYIYQEDSDDKASNIRTET---SPRAQNQHPLIQEHNNNLSELTSSINQMQ 1768 Query: 384 SPWSQLSSETLNQD---TDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXX 440 QLS + D KK + EI L+ + N+ + D + EK Sbjct: 1769 EQVRQLSLDDSELDFYLQQKKEKQLEIDSLKQQLFQQNEVMQDLKQEQIEKQQQIDQLKK 1828 Query: 441 XXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKD 500 D L+ +LQ +Q +E +++ ++ E +K + + + D Sbjct: 1829 ENSNFDELVEELQQSQKQMIEQEIQKKESNQPQEIGG-SEQSEIIKTKSENLELSKKLHD 1887 Query: 501 LIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVR- 559 L + K + QI D + + ++ K N +L + ++ ++ ++++ Sbjct: 1888 LKQSQKQLKNQIANY-DYLILDLETVVADKKNDIQRLNKENQSYQQQNRKQKGRRDLLHK 1946 Query: 560 ----LTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKA 615 L +L L ++ EL++ + LQ + + ++ + D +K ++EN + + Sbjct: 1947 EQNNLQYQLKLLEPQLQELQQTEKQLQESVTQLEE-KLKQLD--EKQKQLENQINQKQQI 2003 Query: 616 ISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASK 675 S LE Q + QE+ Q K +++ +L + ++ + E+K ++ ++ ++ ++ Sbjct: 2004 TSALELQLSTINQEILQQQDKKQQLDSELNQLRD-ENQGIEQEVK-IYRNLSLEDITLNE 2061 Query: 676 KELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISEL 735 + AL + + DK Q Y T++D + ++ +N L +E +L + + A+ + E Sbjct: 2062 QIDALT-KQIHEDK-QTYETLQDEQKATQEQINLLLPQNKEIDELKETAKLQYAQNV-EA 2118 Query: 736 LAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSL 795 L + E Q KI+ + + ++ + + Y+E L R LE+ I E ++ Sbjct: 2119 LNNLQLELQQKIEQKNKVFQEVSDTEKYLEENNHVLQDLNERKANLEDQIKKEEVLVNAV 2178 Query: 796 ERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKN 855 K+ +L L+ +++ Y+ + ++L+ R +V E++L + + E +++Q Sbjct: 2179 SAKSKRLDETLEAEKQNYNVLNAELEDLLKR-------KQVQEQELAKAKEEIQKMQADQ 2231 Query: 856 QILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQ 915 + LL++ Q + +L + + YN +E N + E E + QL+ + + Q Sbjct: 2232 EQLLQQQQQFK-NLKEQIEQYNKDIE-INLKIIPERE--EQLVQLKCIIEKKDEVLSATQ 2287 Query: 916 TLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLN 975 + + K+I++++ + Q E + D+ L + E+ I Q E L++ ++I+ + Sbjct: 2288 AEVDKLNKQIDEIQ-QDKEQKEKELEDQSNLVKSIEEQIIDKYQREKDLKDQLDSIQLKD 2346 Query: 976 MNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALN----QK 1031 + E KM + Q++ S + +Q + ++ LKQ+ + +LN Q+ Sbjct: 2347 LEAELNEKMEQSM----AQQEMLDSIEQLKQQVQQLRDDETQLKQQIQGQESLNNSKKQE 2402 Query: 1032 INNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQ 1091 + Q + + D S AQ +EE+ +++ K K+ +E+ +++ + Sbjct: 2403 LEQKQQEKIELEQDLHSASAQMEEMKFQLEEKNEQLDKLNDQFKKVDEDSKMM-----EA 2457 Query: 1092 IKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFI 1151 + +LKE +L + K E +I +E +++D L + +++ Sbjct: 2458 VLQLKEKEL--KQLQKKKENLI--EELERINNDVVEAQKQLVTQRKKQRSLGAEPQQQDE 2513 Query: 1152 QERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTEND 1211 +Q++ LN+ + +L ++ E T Q+++ + ++ D Sbjct: 2514 NMEEDIQDKITSLNSRNNNLKDDLQKLVEMSPEPTERKPEEQQEVKDAPAPVQVSQFAPD 2573 Query: 1212 NLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQL 1271 + T+ + R ++ + + ++ ++ + FQ +L VQ S F L Sbjct: 2574 RVQQTLQD-RDKKIEILEMTISTLQQQQQERMSMIPSMFQS---KLSVQPSFFMDDDPLL 2629 Query: 1272 LDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEK 1331 L+ T+E E + LQNK++ E L + D + L E++ + Sbjct: 2630 LELQDKFTKES-------ELLKDLQNKIKQTAESHYALSLQLKDWAEKENRLAKELDTRR 2682 Query: 1332 VAFXXXXXXXXXXXXXXXXDLRTENQSYKQ---MQEQSILNINEENAQLKKSSXXXXXXX 1388 + DL +E + Q E + E+ A K Sbjct: 2683 QS-VEQIEFELQAVFAKQSDLESEKVNVLQRIYSLEVETQDFYEQEANTKNKLKEKKDYL 2741 Query: 1389 XXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRI 1448 + +++ K+L+L +++ L E Q + + +E EN +Q L + + + Sbjct: 2742 QTLYKNLIESDQKLLQLRNRMALYSQEGRQLAEQ----VENLENEKENKQQHLQDIQADL 2797 Query: 1449 EDLTYEKESELAILRLKMHENANHYETMQKESEIE-RVKLIEELNVKITESVSLNKQVAE 1507 E + EK+ + A+++ E + ET Q++ ++E + + N ++ + + A Sbjct: 2798 EHVEMEKQEKQALVQSIAKEIS---ETQQEKDKLEIQYATVHSKNQQLKSQIGYEE--AF 2852 Query: 1508 LNKALEE-EVAKTNEMQTALEN 1528 K L+E E+AK + QT +N Sbjct: 2853 YQKLLQELEIAKKRD-QTKFQN 2873 Score = 110 bits (264), Expect = 4e-22 Identities = 211/1180 (17%), Positives = 497/1180 (42%), Gaps = 84/1180 (7%) Query: 446 DTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQE--QLKQELNDEIK---DVNVKD 500 ++ +A ++E+++ + L + D + AK+ E L ++L++E+ + +D Sbjct: 806 ESKLANRKIENEELKK--QLQEANKDYNDQQKRAKMYELYMLNKDLDEEVSLSPKLQEED 863 Query: 501 LI-EKLKSAEEQITQLNDEIDAANK-NMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIV 558 L E+L+ +Q +L D + + +K ++ K+K ++K N + Sbjct: 864 LQNEQLEQLNQQAPELEQPEDPQKQAKKLTIKDKYEKKIKDLKKENRNLIAQLKQLRGAQ 923 Query: 559 RLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEME-NLAETRLKAIS 617 + + + A+L++ ++Q D + ++ K I+++ N + + + Sbjct: 924 QQDQSNRPQQEDDAKLKQSNPSVQN---DNEHPEQVQQQQQPKPIDIQKNTQDLQQQYEK 980 Query: 618 LLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKE 677 LE Q DL+QE+ LQ + +E K+ + + +Q+ +++ ++ + + +E Sbjct: 981 GLEKQ-VDLIQEVQSLQDIIENLEQKVQQKKEAK-EQLEAQLCALDKKNESSQQDPQLQE 1038 Query: 678 LALVIENLKLDKEQLYGT------IKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSA-- 729 A + KLD+E L I L++ D NKL+ L +K +++ A Sbjct: 1039 SATMASTSKLDQEALQRQYDQEVQISRLKDQLADKQNKLEQMEILKEQLKEKEDELKAYK 1098 Query: 730 EKISELLAKIN----HEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESI 785 E+I + N H+++ + T+ D +Q + ++N + + R+ ES Sbjct: 1099 EQIPSIQEYQNQQFLHQQEELVNTELRKD--VQRLEDQLDNQLKLNKELQQRMDNQHESA 1156 Query: 786 AVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIE 845 A++ + ++ S + + ++ E + DELV L D +EK+L+E + Sbjct: 1157 ALLSQKIKLSIHDSNSSSSQIIDNRQRLVEKQQKADELVREHLSLDDLIEDLEKKLVE-K 1215 Query: 846 HENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLES 905 ++ K+ Q NQ+ +Q ++ + VE+ N+ + ++ ++++ Sbjct: 1216 NDYKD-QLLNQLKEGTKPAVQSEANEQPK-----VEQPNQVFAKQQNQEQFVEPIQEISD 1269 Query: 906 NLKRITHEHQTLIV--QKKKEIEDLEIEFNTQ-IESAIRDKKVLNEKYEKNIEYV-TQLE 961 + I++ + + Q + ++ LE + Q I+ +++ N+ + + V Q+ Sbjct: 1270 VQQVISNNEDQISIPLQAGQILQQLEGDSQKQDIKEPNPSQELSNQLHPTKSQPVFAQIN 1329 Query: 962 AQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQK 1021 + +++ + N E ID ++ I +L L++K Sbjct: 1330 QDAEPKLQQVKSSQGFTSPQDLFNKEGIDGQRLQEVWDLLKNNNDADRRIQELRDALQRK 1389 Query: 1022 DEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEEL 1081 ++ L N Q VSD ++ Q +L ++ ++ +L +Q E Sbjct: 1390 NKRKEQLEGVYNKDQELVSQRVSDSVNEKKQLQDQLHQKNLQIAALNDELSKLQQKVFEK 1449 Query: 1082 QILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXX 1141 + ++ E+D + + + K T++ N K + +I S + + NN++ Sbjct: 1450 EKVIDEKDREFRNSQLIK-TYQDNCNKADELI--SKNNQIEETLNNLEVRLAEKQQRVKE 1506 Query: 1142 LKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKS 1201 L++Q + +S + + QE T++ Q E + L G+ + I+QLK+ Sbjct: 1507 LELQIGADSSISNIQDPRESGMIKSYDQEQDTQLQQQEQV---LQGYSM----NIDQLKN 1559 Query: 1202 KLEQLNTENDNLLSTVAELRSSISSAVDQ-RGFEIAELWKQHLAQREADFQKTEHELRVQ 1260 K+EQLN+E T ELR+ ++ Q G+++A+ Q +K +L+ + Sbjct: 1560 KIEQLNSELAERDKTNLELRNQVADLKKQIHGYQLAQ-------QDVKVIKKQNKQLQDE 1612 Query: 1261 LSAF---ESKYEQLLDSVQSSTQEETNKIVTME-QVTSLQNKLQDKEEHLRNLQEKYADV 1316 +SA YE L+ + QE+ +++ ++ ++ + + ++Q E+ ++ Q + Sbjct: 1613 ISALVQDNLNYEDLIRDSEFKLQEKKSRVKELDMEIKNAEIQIQ-VEKQMKENQLLQQKI 1671 Query: 1317 INQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQ 1376 E+++ +E ++ + R NQ+ + +Q+ + + + + Sbjct: 1672 QQTDELIKKNLELDEALTNLELRILDKQQQLSQKEARLSNQNSRILQQPMYIYQEDSDDK 1731 Query: 1377 LKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKT---HEYTITLTQRND- 1432 + + + ELT + ++ Q + E L Q+ + Sbjct: 1732 ASNIRTETSPRAQNQHPLIQEHNNNLSELTSSINQMQEQVRQLSLDDSELDFYLQQKKEK 1791 Query: 1433 --EFENVRQQLVEYEKRIEDLTYEK-ESELAILRLKMHENANHYETMQKESEIERVKLIE 1489 E ++++QQL + + ++DL E+ E + I +LK EN+N E +++ + ++ + + Sbjct: 1792 QLEIDSLKQQLFQQNEVMQDLKQEQIEKQQQIDQLK-KENSNFDELVEELQQSQKQMIEQ 1850 Query: 1490 ELNVK------------ITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLN 1537 E+ K +E + + EL+K L + +++ + N + I+ L Sbjct: 1851 EIQKKESNQPQEIGGSEQSEIIKTKSENLELSKKLHDLKQSQKQLKNQIANYDYLILDLE 1910 Query: 1538 DEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMN 1577 + + +N ++ + + Q + + ++GR + L N Sbjct: 1911 TVVADKKNDIQRLNKENQSYQQ-QNRKQKGRRDLLHKEQN 1949 Score = 99 bits (238), Expect = 5e-19 Identities = 200/996 (20%), Positives = 423/996 (42%), Gaps = 83/996 (8%) Query: 626 LVQELHILQQKYDEVEDKLADISQL-----QSDQVCS-EIKSVHLEEQIDALSASKKELA 679 L+ + HI+ Q+ E+E+ + QL Q++QV + +V L+ QI+ L + +E Sbjct: 31 LMNQEHIIWQQAREIEELRRRLKQLESLDFQNEQVLHLQNINVQLKTQIEFLRSQIQEKD 90 Query: 680 LVIENL-----KLDKEQLYGTIKDL--EN-DKEDIMNKLQNYIQENMDLTDKLEKMSAEK 731 +I L + ++ + L +N ++I+ LQN I N D K Sbjct: 91 AMIAQLTSKPVQAASPEILAAQQQLIQQNLQLQNIIGDLQNQIL-NKDAVIGQLKTQEST 149 Query: 732 ISELLAKINHEEQSKIQ----TQFGID--AKIQERDLYIEN----IESELSKYKSRICRL 781 + +L+ ++ QSK TQ G + + + E Y E IE + +Y+ + Sbjct: 150 LDQLIGQLQSNIQSKRNKVGVTQQGNETLSVLNELQQYPEALQDVIERIIQEYRRMQFLI 209 Query: 782 EESIAVMEDRRYSLERKADQLGSYLQE-KQKAYSEY-TIQEDELVNRLAVLMDHDRVVEK 839 EE +++ + L+ + + + E K++ S + Q +L + A + D +E+ Sbjct: 210 EEKDIEIQNLKSRLQLQQQKANDSISEIKKRDISPIRSDQALDLAKQTASMDDMINDLER 269 Query: 840 QLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTK---- 895 +L+ ++ KELQ K + +N L+ S + V++ + +L ++ K Sbjct: 270 KLMSQDNRKKELQAKLLEVGTQNVELEKQWSQSKDQLPKSVDELVKQNLDVNDKIKELQK 329 Query: 896 ----YQTQLRDLESNLKRITHEHQTLIVQKK-KEIEDLEIEFNT-QIESAIRDKKVLNEK 949 Q +L ++ + I Q L Q+ + ED + NT Q + + D + N++ Sbjct: 330 SLLSKQNELDQVQKQINTINDNQQQLQPQQNLNKQEDQVDKVNTSQNRNNVDDLVLENQQ 389 Query: 950 YEKNI----EYVTQLEAQLQEYKNNIENLNMNVEELNKMNLE----LIDKHVQKQQTQSP 1001 E I + + +AQ ++ +N I+ LN++ + N +L+ L+D + Q+TQ Sbjct: 390 LEDLIVELQQKLVDKQAQKEDIENEIKKLNISALQQNLKDLQKQHGLLDNDNKNQKTQIQ 449 Query: 1002 DYTEQYINEINKLNALLKQKDEEIIALNQKINN---AQVSYMSMVSDYESK-LAQFTT-- 1055 E+ IN+ ++ L Q+++E+ N + + Q ++ + D ++K LA+ T Sbjct: 450 QLQEE-INQNKEIQQKLSQENKELQDQNNQTQSQIKQQEEKLAQLQDQKNKNLAKLTNDD 508 Query: 1056 --KLE---NMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTE 1110 KL+ N EE ++ +QL+ +Q NEEL+ ++QD+Q E + + + ++ + E Sbjct: 509 LLKLQEKFNQTEENNKILEQLV--QQLNEELR--KQQQDNQPLEEELSNIKNKLQKTEQE 564 Query: 1111 GMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQE 1170 + ++ + D NN K + Q+R+ E+ + + + Sbjct: 565 NSDLEQQVQQLEDQLNNFKKQQLQTKESA---KPSYSKSAEQQRTTPVEKFREPFQNIVD 621 Query: 1171 CYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQ 1230 L +LN + V N +S+ + T+ ++ ++ + + + Sbjct: 622 KEEFSFDLGSLNQQDFSSQEVTSSPENIKQSQFAKNKTQEGKFITIPLDIIKNYEYLIRE 681 Query: 1231 RGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSV---QSSTQEETNKIV 1287 + EI EL K LA + + S + L++ Q++ Q ++ V Sbjct: 682 KENEIDEL-KNELANQGLQSIPLNFQTGNMGSDQQENANFQLEATAPNQNNEQNPEDQGV 740 Query: 1288 TMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKV----AFXXXXXXXXX 1343 T+EQ LQ ++ K+++++ L ++ + + Q L E + +K+ Sbjct: 741 TLEQ---LQKTIKTKDDYIQMLLDQIEE-MKQFGSLPEEQQKQKLEGNQKRSDDLVRQNI 796 Query: 1344 XXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVL 1403 DL ++ + K E+ + E N + D E + Sbjct: 797 EIADIIIDLESKLANRKIENEELKKQLQEANKDYNDQQKRAKMYELYMLNKDLDEEVSLS 856 Query: 1404 ELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLV--EYEKRIEDLTYEKESELAI 1461 + +L++ ++ ++ ++ L Q D + ++ + +YEK+I+DL +KE+ I Sbjct: 857 PKLQEEDLQNEQL-EQLNQQAPELEQPEDPQKQAKKLTIKDKYEKKIKDL--KKENRNLI 913 Query: 1462 LRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAK-TN 1520 +LK A + + + + KL ++ N + +QV + + ++ K T Sbjct: 914 AQLKQLRGAQQQDQSNRPQQEDDAKL-KQSNPSVQNDNEHPEQVQQQQQPKPIDIQKNTQ 972 Query: 1521 EMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQK 1556 ++Q E + V L E+ +LQ+++ K+Q+ Sbjct: 973 DLQQQYEKGLEKQVDLIQEVQSLQDIIENLEQKVQQ 1008 Score = 99 bits (238), Expect = 5e-19 Identities = 250/1293 (19%), Positives = 530/1293 (40%), Gaps = 134/1293 (10%) Query: 396 QDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLE 455 Q+ +K N + + LNKDL D+E +S K + +L+ Sbjct: 824 QEANKDYNDQQKRAKMYELYMLNKDL-DEEVSLSPKLQEEDLQNEQLEQLNQQAPELEQP 882 Query: 456 HQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEE-QITQ 514 + L + + ++ K L +L +++ +D + + ++ ++ Q Sbjct: 883 EDPQKQAKKLTIKDKYEKKIKDLKKENRNLIAQLK-QLRGAQQQDQSNRPQQEDDAKLKQ 941 Query: 515 LNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFS--------KVSDSNKEIVRLTEELHH 566 N + N++ +V+ + K +QK + K D +E+ L + + + Sbjct: 942 SNPSVQNDNEHPEQVQQQQQPKPIDIQKNTQDLQQQYEKGLEKQVDLIQEVQSLQDIIEN 1001 Query: 567 LSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDL 626 L QKV + +E K L+ L D + S ++ E +A T L+ Q +D Sbjct: 1002 LEQKVQQKKEAKEQLEAQLCALDK-KNESSQQDPQLQESATMASTSKLDQEALQRQ-YD- 1058 Query: 627 VQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIE--N 684 QE+ I + K D++ DK + Q+ EI L+E+ D L A K+++ + E N Sbjct: 1059 -QEVQISRLK-DQLADKQNKLEQM-------EILKEQLKEKEDELKAYKEQIPSIQEYQN 1109 Query: 685 LKL--DKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKM--SAEKISELLAKIN 740 + +E+L T +L D + + ++L N ++ N +L +++ SA +S+ + Sbjct: 1110 QQFLHQQEELVNT--ELRKDVQRLEDQLDNQLKLNKELQQRMDNQHESAALLSQKIKLSI 1167 Query: 741 HEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKAD 800 H+ S ++ E+ + + E I LE+ + D + L + Sbjct: 1168 HDSNSSSSQIIDNRQRLVEKQQKADELVREHLSLDDLIEDLEKKLVEKNDYKDQLLNQLK 1227 Query: 801 QLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVE--KQLLEIEHENKELQKKNQIL 858 + G+ + +A + +++ V A + ++ VE +++ +++ + + I Sbjct: 1228 E-GTKPAVQSEANEQPKVEQPNQV--FAKQQNQEQFVEPIQEISDVQQVISNNEDQISIP 1284 Query: 859 LEENQNLQISLSDMQQHY----NALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEH 914 L+ Q LQ D Q+ N E +N+ +S+ Q +D E L+++ Sbjct: 1285 LQAGQILQQLEGDSQKQDIKEPNPSQELSNQLHPTKSQPVFAQIN-QDAEPKLQQVKSSQ 1343 Query: 915 QTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENL 974 Q E ++ + ++ +++ N ++ I+ + + + K +E + Sbjct: 1344 GFTSPQDLFNKEGIDGQRLQEVWDLLKN----NNDADRRIQELRDALQRKNKRKEQLEGV 1399 Query: 975 -NMNVEELNKMNLELID--KHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQK 1031 N + E +++ + ++ K +Q Q Q +E++KL + +K++ I +++ Sbjct: 1400 YNKDQELVSQRVSDSVNEKKQLQDQLHQKNLQIAALNDELSKLQQKVFEKEKVIDEKDRE 1459 Query: 1032 INNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILV------ 1085 N+Q+ + D +K + +K +EE + + +L + +Q +EL++ + Sbjct: 1460 FRNSQL--IKTYQDNCNKADELISKNNQIEETLNNLEVRLAEKQQRVKELELQIGADSSI 1517 Query: 1086 ----------------REQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVD 1129 +EQD Q+++ ++ + MNI + + + IE ++ + D Sbjct: 1518 SNIQDPRESGMIKSYDQEQDTQLQQQEQVLQGYSMNIDQ-----LKNKIEQLNSELAERD 1572 Query: 1130 XXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHD 1189 LK Q + ++ V + K N +LQ+ + ++Q + LN E D Sbjct: 1573 KTNLELRNQVADLKKQIHGYQLAQQDV--KVIKKQNKQLQDEISALVQ-DNLNYEDLIRD 1629 Query: 1190 VVNQEQINQLKSKLEQLNTENDNL-LSTVAELRSSISSAVDQRGFEIAELWKQHLAQREA 1248 ++ ++ + KS++++L+ E N + E + + + Q+ + EL K++L E Sbjct: 1630 --SEFKLQEKKSRVKELDMEIKNAEIQIQVEKQMKENQLLQQKIQQTDELIKKNL---EL 1684 Query: 1249 DFQKTEHELRV-----QLSAFESKYE----QLLDSVQSSTQEETN-KIVTMEQVTS--LQ 1296 D T ELR+ QLS E++ ++L QE+++ K + TS Q Sbjct: 1685 DEALTNLELRILDKQQQLSQKEARLSNQNSRILQQPMYIYQEDSDDKASNIRTETSPRAQ 1744 Query: 1297 NKLQDKEEHLRNLQEKYADVINQIEILRS-EIEDEKVAFXXXXXXXXXXXXXXXXDLRTE 1355 N+ +EH NL E + + E +R ++D ++ F + Sbjct: 1745 NQHPLIQEHNNNLSELTSSINQMQEQVRQLSLDDSELDFYLQQKKEKQLEIDSLKQQLFQ 1804 Query: 1356 NQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXX---XXXRVNDAEAKVLELTHQLELK 1412 Q +Q + ++ QLKK + ++ + E + E E+ Sbjct: 1805 QNEVMQDLKQEQIEKQQQIDQLKKENSNFDELVEELQQSQKQMIEQEIQKKESNQPQEIG 1864 Query: 1413 DSEIYQ--KTHEYTITLTQRNDEFEN----VRQQLVEYEKRIEDL-TYEKESELAILRLK 1465 SE + KT + L+++ + + ++ Q+ Y+ I DL T + + I RL Sbjct: 1865 GSEQSEIIKTKSENLELSKKLHDLKQSQKQLKNQIANYDYLILDLETVVADKKNDIQRLN 1924 Query: 1466 MHENANHYETMQKESEIERVKLIEELNVK---------ITESVSLNKQVAELNKALEEEV 1516 EN ++ + +K+ + E+ N++ + E KQ+ E LEE++ Sbjct: 1925 K-ENQSYQQQNRKQKGRRDLLHKEQNNLQYQLKLLEPQLQELQQTEKQLQESVTQLEEKL 1983 Query: 1517 AKTNEMQTALENQ-----------EIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTK 1565 + +E Q LENQ E+++ T+N EI Q+ + S++ + D Sbjct: 1984 KQLDEKQKQLENQINQKQQITSALELQLSTINQEILQQQDKKQQLDSELNQ----LRDEN 2039 Query: 1566 QGRDEQLDNTMNKELLDAVPRAELDLAMYMLHQ 1598 QG ++++ N L D ++D +H+ Sbjct: 2040 QGIEQEVKIYRNLSLEDITLNEQIDALTKQIHE 2072 Score = 98.7 bits (235), Expect = 1e-18 Identities = 193/1013 (19%), Positives = 415/1013 (40%), Gaps = 86/1013 (8%) Query: 147 LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXX 206 L T K+ +++ L+ K+K ++ L+ +IN+K QI A Sbjct: 1965 LQQTEKQLQESVTQLEEKLKQLDEKQKQLENQINQKQQI----TSALELQLSTINQEILQ 2020 Query: 207 XXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDI---ESKDVRISSLEEANKLLEAA 263 + ++ ++++ +E E K + L+DI E D + E + E Sbjct: 2021 QQDKKQQLDSELNQLRDENQGIEQEVKIYRNLSLEDITLNEQIDALTKQIHEDKQTYETL 2080 Query: 264 RFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTE 323 + E ++ L Q A Q++E + E+++K + E Sbjct: 2081 QDEQKATQEQINLLLPQNKEIDELKETAKLQYA-QNVEALNNLQLELQQKIEQKNKVFQE 2139 Query: 324 LTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMK 383 ++ + LE N ++ N+ N + E V++ S K L T K Sbjct: 2140 VSDTEKYLEENNHVLQDLNERKANLEDQIKKEEVLVNAVSAKSKRL------DETLEAEK 2193 Query: 384 SPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKD---LVDKEY-------VISEKDT 433 ++ L++E + K++ + E+AK + IQ + D L+ ++ I + + Sbjct: 2194 QNYNVLNAELEDLLKRKQVQEQELAKAKEEIQKMQADQEQLLQQQQQFKNLKEQIEQYNK 2253 Query: 434 XXXXXXXXXXGKDTLIAQLQ--LEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELND 491 ++ + QL+ +E + + + V + ++EI + +EQ ++EL D Sbjct: 2254 DIEINLKIIPEREEQLVQLKCIIEKKDEVLSATQAEVDKLNKQIDEIQQDKEQKEKELED 2313 Query: 492 EIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVS 551 + VK + E++ ++ L D++D+ ++ + N K++ Q+ + + Sbjct: 2314 QSN--LVKSIEEQIIDKYQREKDLKDQLDSIQLKDLEAELNEKMEQSMAQQ--EMLDSIE 2369 Query: 552 DSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRM-IESDVYKKMIEMENL-- 608 +++ +L ++ L Q++ E + + L ++ +E D++ +ME + Sbjct: 2370 QLKQQVQQLRDDETQLKQQIQGQESLNNSKKQELEQKQQEKIELEQDLHSASAQMEEMKF 2429 Query: 609 -AETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVH---L 664 E + + + L Q F V E + + ++++K Q + + + E++ ++ + Sbjct: 2430 QLEEKNEQLDKLNDQ-FKKVDEDSKMMEAVLQLKEKELKQLQKKKENLIEELERINNDVV 2488 Query: 665 EEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKL 724 E Q ++ KK+ +L E + D EN +EDI +K+ + N +L D L Sbjct: 2489 EAQKQLVTQRKKQRSLGAEPQQQD-----------ENMEEDIQDKITSLNSRNNNLKDDL 2537 Query: 725 EKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEES 784 +K+ ++S + EEQ +++ A +Q + ++ L +I LE + Sbjct: 2538 QKL--VEMSPEPTERKPEEQQEVK---DAPAPVQVSQFAPDRVQQTLQDRDKKIEILEMT 2592 Query: 785 IAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRL--------AVLMDHDRV 836 I+ ++ ++ + + + S Q K + + +D L+ L +L D Sbjct: 2593 ISTLQQQQ---QERMSMIPSMFQSKLSVQPSFFMDDDPLLLELQDKFTKESELLKDLQNK 2649 Query: 837 VEKQLLEIEH----ENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESE 892 + KQ E + + K+ +K L +E + S+ ++ A+ A ++DL ESE Sbjct: 2650 I-KQTAESHYALSLQLKDWAEKENRLAKELDTRRQSVEQIEFELQAVF--AKQSDL-ESE 2705 Query: 893 STKYQTQLRDLESNLKRITHEHQTLIVQKKKEIED-LEIEFNTQIESAIRDKKVLNEKYE 951 ++ LE + +E + K KE +D L+ + IES D+K+L + Sbjct: 2706 KVNVLQRIYSLEVETQDF-YEQEANTKNKLKEKKDYLQTLYKNLIES---DQKLL--QLR 2759 Query: 952 KNIEYVTQLEAQLQEYKNNIENLNMNVEE-LNKMNLELIDKHVQKQQTQS-PDYTEQYIN 1009 + +Q QL E N+EN N ++ L + +L ++KQ+ Q+ + I+ Sbjct: 2760 NRMALYSQEGRQLAEQVENLENEKENKQQHLQDIQADLEHVEMEKQEKQALVQSIAKEIS 2819 Query: 1010 EINKLNALLKQKDEEIIALNQKINN----AQVSYMSMVSDYESKLAQFTTKLENMEEEMQ 1065 E + L+ + + + NQ++ + + Y ++ + E + TK +N+ + Sbjct: 2820 ETQQEKDKLEIQYATVHSKNQQLKSQIGYEEAFYQKLLQELEIAKKRDQTKFQNLFSDGS 2879 Query: 1066 RVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTI 1118 ++ L+ + L R + + +LKE + I E I TI Sbjct: 2880 TQTEYDLEQFESLSTCTQLYRITKEDVYQLKENCKQRLIQIYTNENANIQQTI 2932 Score = 98.7 bits (235), Expect = 1e-18 Identities = 199/997 (19%), Positives = 424/997 (42%), Gaps = 92/997 (9%) Query: 150 TIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXX 209 T+ E+ +AL+ + K T+ D Q+ E+ ++ +NK Sbjct: 2058 TLNEQIDALTKQIHEDKQTYETLQDEQKATQEQINLLLPQNKEIDELKETAKLQYAQNVE 2117 Query: 210 XXEDTKQQMTKM--QENFIAMEA----EWKDEKQRLLKDIESKDVRISSLEEANKLLEAA 263 + + ++ + Q+N + E ++ +E +L+D+ R ++LE+ K E Sbjct: 2118 ALNNLQLELQQKIEQKNKVFQEVSDTEKYLEENNHVLQDLNE---RKANLEDQIKKEEVL 2174 Query: 264 RFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTE 323 +S + +L + LE L K+ + +E + +E+ A+ + Sbjct: 2175 VNAVSAKSKRLDETLEAEKQNYNVLNAELEDLLKRK-QVQEQELAKAKEEIQKMQADQEQ 2233 Query: 324 LTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMK 383 L ++ + ++L QI Q NK++E L + + + +I +K +A++ + Sbjct: 2234 LLQQQQQFKNLKEQIEQYNKDIEINLKIIPEREEQLVQLKC----IIEKKDEVLSATQAE 2289 Query: 384 SPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXX 443 + + QD ++K + E+ +++S+ + ++DK EKD Sbjct: 2290 VDKLNKQIDEIQQDKEQK--EKELEDQSNLVKSIEEQIIDKYQ--REKDLKDQLDSIQL- 2344 Query: 444 GKDTLIAQLQLEHQQHMEGPSLIH-VGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLI 502 KD L A+L + +Q M ++ + + V ++ + QLKQ++ + N K Sbjct: 2345 -KD-LEAELNEKMEQSMAQQEMLDSIEQLKQQVQQLRDDETQLKQQIQGQESLNNSKK-- 2400 Query: 503 EKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNK---EIVR 559 ++L+ +++ +L ++ +A+ M ++K + K +Q+ K D F KV + +K +++ Sbjct: 2401 QELEQKQQEKIELEQDLHSASAQMEEMKFQLEEKNEQLDKLNDQFKKVDEDSKMMEAVLQ 2460 Query: 560 LTE-ELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKM-----IEMENLAETRL 613 L E EL L +K L EE + +V+ + + + + + EN+ E Sbjct: 2461 LKEKELKQLQKKKENLIEELERINNDVVEAQKQLVTQRKKQRSLGAEPQQQDENMEEDIQ 2520 Query: 614 KAISLLESQKFDLVQELHIL-----------QQKYDEVEDKLA--DISQLQSDQVCSEI- 659 I+ L S+ +L +L L ++ EV+D A +SQ D+V + Sbjct: 2521 DKITSLNSRNNNLKDDLQKLVEMSPEPTERKPEEQQEVKDAPAPVQVSQFAPDRVQQTLQ 2580 Query: 660 ---KSVH-LEEQIDALSASKKELALVIENL---KL--------DKEQLYGTIKDLENDKE 704 K + LE I L ++E +I ++ KL D + L ++D + Sbjct: 2581 DRDKKIEILEMTISTLQQQQQERMSMIPSMFQSKLSVQPSFFMDDDPLLLELQDKFTKES 2640 Query: 705 DIMNKLQNYIQENMDLTDKLE---KMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERD 761 +++ LQN I++ + L K AEK + L +++ QS Q +F + A ++ Sbjct: 2641 ELLKDLQNKIKQTAESHYALSLQLKDWAEKENRLAKELDTRRQSVEQIEFELQAVFAKQS 2700 Query: 762 LYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQED 821 ++ESE RI LE ++ + + K + YLQ K E + Sbjct: 2701 ----DLESEKVNVLQRIYSLEVETQDFYEQEANTKNKLKEKKDYLQTLYKNLIESDQKLL 2756 Query: 822 ELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVE 881 +L NR+A+ R + +Q+ +E+E + Q+ Q + + +++++ + Q ++ + Sbjct: 2757 QLRNRMALYSQEGRQLAEQVENLENEKENKQQHLQDIQADLEHVEMEKQEKQALVQSIAK 2816 Query: 882 KANRT----DLAESESTKYQTQLRDLESNLKRITHEHQTLI----VQKKKE---IEDLEI 930 + + T D E + ++ + L+S + +Q L+ + KK++ ++L Sbjct: 2817 EISETQQEKDKLEIQYATVHSKNQQLKSQIGYEEAFYQKLLQELEIAKKRDQTKFQNLFS 2876 Query: 931 EFNTQIESAIRDKKVLN---EKYEKNIEYVTQLEAQLQEYKNNI-ENLNMNVEELNKMNL 986 + +TQ E + + L+ + Y E V QL+ ++ I N N N+++ N Sbjct: 2877 DGSTQTEYDLEQFESLSTCTQLYRITKEDVYQLKENCKQRLIQIYTNENANIQQTINQNK 2936 Query: 987 ELIDKHVQKQQTQSPDYTEQYINEI---NKLNALLKQKDEEIIALNQKINNAQVSYMSMV 1043 L K + QQ + +N I ++ ++ L ++ N K++ Q+ +M Sbjct: 2937 HL-QKMIHLQQMIIQIQENENVNLIEFQSRRSSRLGLNVMDLSIYNMKLDLEQIDFMM-- 2993 Query: 1044 SDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEE 1080 ++KL + + ++++Q + KQ + E Sbjct: 2994 --NKTKLVEVHVSDNQIVVADTKIARQWIVDKQFDYE 3028 Score = 97.5 bits (232), Expect = 3e-18 Identities = 224/1200 (18%), Positives = 494/1200 (41%), Gaps = 106/1200 (8%) Query: 216 QQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLA 275 +++ QE+ I +A +E +R LK +ES D + + + + +I S++ Sbjct: 28 EELLMNQEHIIWQQAREIEELRRRLKQLESLDFQNEQVLHLQNINVQLKTQIEFLRSQIQ 87 Query: 276 QE---LEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLE 332 ++ + Q A+Q + + I +I N + +++ E Sbjct: 88 EKDAMIAQLTSKPVQAASPEILAAQQQLIQQNLQLQNIIGDLQNQILNKDAVIGQLKTQE 147 Query: 333 H-LNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSS 391 L+ I Q +++K +G + + S ++ ++ ++ + ++ Sbjct: 148 STLDQLIGQLQSNIQSKRNKVGVTQQGNETLSVLNELQQYPEALQDVIERIIQEYRRM-- 205 Query: 392 ETLNQDTDKKINKNEIAKLEMVIQSLNKDL--VDKEYVISEKDTXXXXXXXXXXGKDTLI 449 + L ++ D +I +N ++L++ Q N + + K + + D +I Sbjct: 206 QFLIEEKDIEI-QNLKSRLQLQQQKANDSISEIKKRDISPIRSDQALDLAKQTASMDDMI 264 Query: 450 AQLQ--LEHQQHMEGP---SLIHVGT-NTEDVNEIAKVQEQLKQELNDEIK---DVN--V 498 L+ L Q + + L+ VGT N E + ++ ++QL + +++ +K DVN + Sbjct: 265 NDLERKLMSQDNRKKELQAKLLEVGTQNVELEKQWSQSKDQLPKSVDELVKQNLDVNDKI 324 Query: 499 KDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQ----KTIDNFSKVSDSN 554 K+L + L S + ++ Q+ +I+ N N +++ L ++ Q T N + V D Sbjct: 325 KELQKSLLSKQNELDQVQKQINTINDNQQQLQPQQNLNKQEDQVDKVNTSQNRNNVDDLV 384 Query: 555 KEIVRLTEELHHLSQKVAELEEEKGN------------LQLHLVDYDSGR-MIESDVYKK 601 E +L + + L QK+ + + +K + LQ +L D ++++D + Sbjct: 385 LENQQLEDLIVELQQKLVDKQAQKEDIENEIKKLNISALQQNLKDLQKQHGLLDNDNKNQ 444 Query: 602 MIEMENLAE--TRLKAISL-LESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSE 658 +++ L E + K I L + +L + + Q + + E+KLA + ++ + Sbjct: 445 KTQIQQLQEEINQNKEIQQKLSQENKELQDQNNQTQSQIKQQEEKLAQLQDQKNKNLAKL 504 Query: 659 IKS--VHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQE 716 + L+E+ + + K L +++ L + + + LE + +I NKLQ QE Sbjct: 505 TNDDLLKLQEKFNQTEENNKILEQLVQQLNEELRKQQQDNQPLEEELSNIKNKLQKTEQE 564 Query: 717 NMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKS 776 N DL +++++ + + ++ +E +K + A+ Q+R +E Sbjct: 565 NSDLEQQVQQLEDQLNNFKKQQLQTKESAK--PSYSKSAE-QQRTTPVEKFREPFQNIVD 621 Query: 777 RICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVN-RLAVLMDHDR 835 + + + + +S + + S KQ +++ QE + + L ++ +++ Sbjct: 622 KE-EFSFDLGSLNQQDFSSQ---EVTSSPENIKQSQFAKNKTQEGKFITIPLDIIKNYEY 677 Query: 836 VVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTK 895 ++ ++ EI+ EL + + N SD Q++ N +E E Sbjct: 678 LIREKENEIDELKNELANQGLQSIPLNFQTGNMGSDQQENANFQLEATAPNQNNEQNPED 737 Query: 896 YQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIE 955 L L+ +K Q L+ Q ++ + + Q + ++K ++ +NIE Sbjct: 738 QGVTLEQLQKTIKTKDDYIQMLLDQIEEMKQFGSLPEEQQKQKLEGNQKRSDDLVRQNIE 797 Query: 956 ---YVTQLEAQLQEYKNNIENLNMNVEELNK-----------MNLELIDKHVQKQQTQSP 1001 + LE++L K E L ++E NK L +++K + ++ + SP Sbjct: 798 IADIIIDLESKLANRKIENEELKKQLQEANKDYNDQQKRAKMYELYMLNKDLDEEVSLSP 857 Query: 1002 -----DYTEQYINEINKLNALLK-----QKDEEIIAL----NQKINNAQVSYMSMVSDYE 1047 D + + ++N+ L+ QK + + + +KI + + ++++ + Sbjct: 858 KLQEEDLQNEQLEQLNQQAPELEQPEDPQKQAKKLTIKDKYEKKIKDLKKENRNLIAQLK 917 Query: 1048 S-KLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQD-----DQIKELKETKLT 1101 + AQ + ++E KQ S Q++ E V++Q D K ++ + Sbjct: 918 QLRGAQQQDQSNRPQQEDDAKLKQSNPSVQNDNEHPEQVQQQQQPKPIDIQKNTQDLQQQ 977 Query: 1102 FEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQ-----EEEEFIQERSV 1156 +E + K +I ++ + D N++ L+ Q ++ E Q+ Sbjct: 978 YEKGLEKQVDLI--QEVQSLQDIIENLEQKVQQKKEAKEQLEAQLCALDKKNESSQQDPQ 1035 Query: 1157 LQE-----QSAKLNTE-LQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTEN 1210 LQE ++KL+ E LQ Y + +Q+ L +L Q ++ Q++ EQL + Sbjct: 1036 LQESATMASTSKLDQEALQRQYDQEVQISRLKDQLAD----KQNKLEQMEILKEQLKEKE 1091 Query: 1211 DNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQ 1270 D L + ++ S Q + EL L + D Q+ E +L QL + +Q Sbjct: 1092 DELKAYKEQIPSIQEYQNQQFLHQQEELVNTELRK---DVQRLEDQLDNQLK-LNKELQQ 1147 Query: 1271 LLDSVQSSTQEETNKI-VTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIED 1329 +D+ S + KI +++ S +++ D + L Q+K +++ + L IED Sbjct: 1148 RMDNQHESAALLSQKIKLSIHDSNSSSSQIIDNRQRLVEKQQKADELVREHLSLDDLIED 1207 Score = 70.5 bits (165), Expect = 4e-10 Identities = 122/578 (21%), Positives = 253/578 (43%), Gaps = 71/578 (12%) Query: 800 DQLGSYLQEKQKAYSEYTIQEDE--LVNRLAVLMDHDRVVE------KQLLEIEHENKEL 851 +Q S LQ K + TIQE E L+N+ ++ R +E KQL ++ +N+++ Sbjct: 7 EQCVSKLQGHLKGATA-TIQEIEELLMNQEHIIWQQAREIEELRRRLKQLESLDFQNEQV 65 Query: 852 QKKNQILLEENQNLQISLSDMQQHYNALVEKANR-TDLAESESTKYQTQLRDLESNLKRI 910 I ++ ++ S +Q+ + + ++ A E Q QL L+ I Sbjct: 66 LHLQNINVQLKTQIEFLRSQIQEKDAMIAQLTSKPVQAASPEILAAQQQLIQQNLQLQNI 125 Query: 911 THEHQTLIVQKKKEIEDLEIEFNT------QIESAIRDKKVLNEKYEKNIEYVTQLEAQL 964 + Q I+ K I L+ + +T Q++S I+ K+ ++ E ++ L +L Sbjct: 126 IGDLQNQILNKDAVIGQLKTQESTLDQLIGQLQSNIQSKRNKVGVTQQGNETLSVLN-EL 184 Query: 965 QEYKNNIEN-LNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDE 1023 Q+Y +++ + ++E +M + +K ++ Q +S +Q + N + +K++D Sbjct: 185 QQYPEALQDVIERIIQEYRRMQFLIEEKDIEIQNLKSRLQLQQ--QKANDSISEIKKRDI 242 Query: 1024 EIIALNQKINNAQ--VSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLD-SKQHNEE 1080 I +Q ++ A+ S M++D E KL + + ++ ++ V Q ++ KQ ++ Sbjct: 243 SPIRSDQALDLAKQTASMDDMINDLERKLMSQDNRKKELQAKLLEVGTQNVELEKQWSQS 302 Query: 1081 LQILVREQD----------DQIKELKETKLTFEMNIPKTEGMIIS-----------STIE 1119 L + D D+IKEL+++ L+ + + + + I + + Sbjct: 303 KDQLPKSVDELVKQNLDVNDKIKELQKSLLSKQNELDQVQKQINTINDNQQQLQPQQNLN 362 Query: 1120 PMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQE--RSVLQEQSAK--LNTELQECYTKI 1175 D + V+ L+ Q+ E+ I E + ++ +Q+ K + E+++ Sbjct: 363 KQEDQVDKVNTSQNRNNVDDLVLENQQLEDLIVELQQKLVDKQAQKEDIENEIKKLNISA 422 Query: 1176 IQ--LETLNTE--LTGHDVVNQ--------EQINQ---LKSKLEQLNTE----NDNLLST 1216 +Q L+ L + L +D NQ E+INQ ++ KL Q N E N+ S Sbjct: 423 LQQNLKDLQKQHGLLDNDNKNQKTQIQQLQEEINQNKEIQQKLSQENKELQDQNNQTQSQ 482 Query: 1217 VAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQ 1276 + + ++ DQ+ +A+L L + + F +TE ++ + E+L Q Sbjct: 483 IKQQEEKLAQLQDQKNKNLAKLTNDDLLKLQEKFNQTEENNKILEQLVQQLNEELRKQQQ 542 Query: 1277 SST--QEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEK 1312 + +EE + I Q T +N D E+ ++ L+++ Sbjct: 543 DNQPLEEELSNIKNKLQKTEQENS--DLEQQVQQLEDQ 578 Score = 68.5 bits (160), Expect = 1e-09 Identities = 121/660 (18%), Positives = 279/660 (42%), Gaps = 50/660 (7%) Query: 961 EAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQ 1020 E + + + +++ ++E+ ++ + +H+ QQ + + + + ++ L+ Sbjct: 7 EQCVSKLQGHLKGATATIQEIEELLMN--QEHIIWQQAREIEELRRRLKQLESLDF---- 60 Query: 1021 KDEEIIALNQKIN---NAQVSYM-SMVSDYESKLAQFTTK-LENMEEEMQRVSKQLLDSK 1075 ++E+++ L Q IN Q+ ++ S + + ++ +AQ T+K ++ E+ +QL+ Sbjct: 61 QNEQVLHL-QNINVQLKTQIEFLRSQIQEKDAMIAQLTSKPVQAASPEILAAQQQLI--- 116 Query: 1076 QHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXX 1135 Q N +LQ ++ + +QI K+ + T +I + N V Sbjct: 117 QQNLQLQNIIGDLQNQILN-KDAVIGQLKTQESTLDQLIGQLQSNIQSKRNKVGVTQQGN 175 Query: 1136 XXXXXXLKVQEEEEFIQE--RSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQ 1193 ++Q+ E +Q+ ++QE ++ ++E K I+++ L + L Sbjct: 176 ETLSVLNELQQYPEALQDVIERIIQEYR-RMQFLIEE---KDIEIQNLKSRLQLQQQKAN 231 Query: 1194 EQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVD-QRGFEIAELWKQHLAQREADFQK 1252 + I+++K K + +D L + S D +R + K+ L + + Sbjct: 232 DSISEIK-KRDISPIRSDQALDLAKQTASMDDMINDLERKLMSQDNRKKELQAKLLEVGT 290 Query: 1253 TEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQ-VTSLQNKLQDKEEHLRNLQE 1311 EL Q S + + + +D + + +KI +++ + S QN+L ++ + + + Sbjct: 291 QNVELEKQWSQSKDQLPKSVDELVKQNLDVNDKIKELQKSLLSKQNELDQVQKQINTIND 350 Query: 1312 KYADVINQIEILRSEIEDEKV--AFXXXXXXXXXXXXXXXXDLRTENQSY---KQMQEQS 1366 + Q + + E + +KV + DL E Q KQ Q++ Sbjct: 351 NQQQLQPQQNLNKQEDQVDKVNTSQNRNNVDDLVLENQQLEDLIVELQQKLVDKQAQKED 410 Query: 1367 ILN-INEENAQLKKSSXXXXXXXXXXXXRVN-DAEAKVLELTHQLELKDSEIYQKTHEYT 1424 I N I + N + + N + + ++ +L ++ ++ EI QK + Sbjct: 411 IENEIKKLNISALQQNLKDLQKQHGLLDNDNKNQKTQIQQLQEEIN-QNKEIQQKLSQEN 469 Query: 1425 ITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILR----LKMHENANHYETMQKES 1480 L +N++ ++ Q+ + E+++ L +K LA L LK+ E N E K Sbjct: 470 KELQDQNNQTQS---QIKQQEEKLAQLQDQKNKNLAKLTNDDLLKLQEKFNQTEENNKIL 526 Query: 1481 EIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEI 1540 E +L+++LN ++ + N+ + E ++ ++ KT + + LE Q + L D++ Sbjct: 527 E----QLVQQLNEELRKQQQDNQPLEEELSNIKNKLQKTEQENSDLEQQ---VQQLEDQL 579 Query: 1541 TNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDLAMYMLHQRD 1600 N + + +K S++ +Q R ++ + + V + E + L+Q+D Sbjct: 580 NNFKK--QQLQTKESAKPSYSKSAEQQRTTPVEK-FREPFQNIVDKEEFSFDLGSLNQQD 636 >UniRef50_UPI00006CA483 Cluster: hypothetical protein TTHERM_00497680; n=1; Tetrahymena thermophila SB210|Rep: hypothetical protein TTHERM_00497680 - Tetrahymena thermophila SB210 Length = 2240 Score = 165 bits (400), Expect = 1e-38 Identities = 262/1311 (19%), Positives = 561/1311 (42%), Gaps = 116/1311 (8%) Query: 330 LLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQL 389 L+ L +I + + E+ L + + S S I ++ + +K+ QL Sbjct: 180 LVNQLKLEIEVLSNKYEDALERLAASERKTPSQQINNSEQIHQQIDDISVAKIDYLQKQL 239 Query: 390 SSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVIS-EKDTXXXXXXXXXXGKDTL 448 L + +K+ K VI L KDL ++ EK D L Sbjct: 240 QLSQLQLEKEKE-------KALKVILKLEKDLDGQQSSFDFEKLKLSSQIESLNAINDQL 292 Query: 449 IAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKL--- 505 Q ++ + ++ S++ + +D + K + Q L D+I +N ++K Sbjct: 293 --QKEINKLKSIQKESVL-ISQEKDDAESVVKELRKQNQMLTDQINSLNQNFNLQKQSQD 349 Query: 506 KSAEEQITQLNDEIDAANKNMIKVKS------NHKLKLKQMQKTIDNFSKVSDSNKEIVR 559 K ++ + L ++ + K ++ +K+ N K +++ +Q +F V+ S ++ Sbjct: 350 KQDKQTLIILQEQTEKFEKEILVLKNQKQEDENLKQQIQLIQLEKSDFLSVNQSLRQNQS 409 Query: 560 LTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLL 619 + E+ + Q ++ E EK V S + SD ++ E+ + + I +L Sbjct: 410 VLEDQLQILQSQSQ-ENEK-------VKRSSAK---SDFEREKNELVQNIKNLEQQILVL 458 Query: 620 ESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELA 679 + Q FD +Q ++++ +++ +I + Q E + ++ + D L +SK+E Sbjct: 459 KKQNFDDLQNNKKIEEQDLQIQKLKNEIREATIKQQKLEQLNGQIQLECDILRSSKRENE 518 Query: 680 LVIENLKL-------DKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEK--MSAE 730 E K DK+Q+ ++D N+ + + +LQ + +++ LEK + Sbjct: 519 QSQEQRKQLYEKAINDKDQIIKQLRDTLNENQQMFQQLQTQLNIKIEIIANLEKENQNTR 578 Query: 731 KISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMED 790 K+ E + ++ +++TQ + +I++++ +E I+S + L+E ++ E Sbjct: 579 KLYEDRLTTSQQDFEQLKTQ--LKDQIEQKNKQVEQIQSSFMRDMEL---LKEQFSLKEA 633 Query: 791 RRYSLERKAD----QLGSYLQEKQ---KAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLE 843 + ++++AD QL ++EKQ + Y + ++ L L ++++L Sbjct: 634 EQLDIQKQADEMRQQLLDVIEEKQSWLQKYEKVFAEQQSLSESLGKSQKECNSLQEKLFS 693 Query: 844 IEH-ENKELQK----KNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQT 898 +++ E K+L+ KN+I + Q Q S + ++Q + E N+ L E+ K T Sbjct: 694 LQNVEQKQLEDILKLKNEIQIASGQQGQAS-NQLKQANQKIQELENKIILLNLENQKVIT 752 Query: 899 QLRDLESNLKRITHEHQTLIVQK---KKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIE 955 + ++ L + HE L Q K ++E L+ + + + +V+ + ++ E Sbjct: 753 EKEEINFKLNQANHEQDILKKQNEEFKNQLEQLKNQILQEKNKSNEQNQVIQKLQQQAKE 812 Query: 956 YVTQLEA------QLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYIN 1009 E LQ+++ + ++ +E+ N +N++ K + K +Q D ++ IN Sbjct: 813 EEVLKENLMSKIDSLQQFQQKYHDASLQLEQFN-INIQEFQKQI-KDLSQIKDESQIKIN 870 Query: 1010 EINKLNALLKQ---KDEEIIA-LNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQ 1065 ++N N Q K++E+ + L ++ + Q+ + S+ KL+ EE+ Q Sbjct: 871 KLNSENYEATQQLMKEQELNSTLKGEVQHLQLQITQKNGELSSQYELLNNKLKEYEEKEQ 930 Query: 1066 RVSKQLLDSK-QHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDD 1124 ++ Q+ K Q E+ Q L++E+D+ +L ++ + + K + + E D Sbjct: 931 KLLIQISQLKIQDQEQEQKLIKERDELHSKLINLDISTQNIMSKHQEE--RNNYERKLFD 988 Query: 1125 ANNV--DXXXXXXXXXXXXLKVQEEEEFIQERSVL-QEQSAKLNTELQECYTKIIQLETL 1181 NN+ + +V E E ++E + Q Q ++L +L+E I + Sbjct: 989 LNNLCNEAKQQNILSTDKLTQVTRELEQLKETNKQKQNQVSELTLKLEEVTKLKITDSSK 1048 Query: 1182 NTELTGH-DVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWK 1240 EL D V QE+ ++K +E L D L+++ ++ I+ + Q I EL + Sbjct: 1049 IQELQSQVDFVKQEKDREIKKSIE-LQKNLDGLIASTSQKDQEINLSKIQ----IQELNR 1103 Query: 1241 QHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQE-ETNKIVTMEQVTSLQNKL 1299 Q L E T + Q+ + YE+ L + + ++ + +K++ E++ L K Sbjct: 1104 QILVSNE-----TIQSYKKQVDNLQESYEKQLSELSTFNEDLKRSKLLDDERIQELTMKT 1158 Query: 1300 QDKEEH--LRNLQ-----EKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDL 1352 EE LRN Q E + ++ ++L ++E EK F +L Sbjct: 1159 SQIEEQMDLRNSQHLQMSEFRKNEEHRFQLLCQQMEIEKQQFLKDIQDLTLKLEKCEKEL 1218 Query: 1353 RTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDA--EAKV---LELTH 1407 E + EQ EE +QL K ++ E K+ L+L Sbjct: 1219 DEEKNQFIYQLEQ----FREEKSQLLKQIEEEKSIKENTIFQIQQQFEEQKIQFSLKLND 1274 Query: 1408 QLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEK--RIEDLTYEKESELAILRLK 1465 + +D I E+ + + E E++R Q+ E ++ I+ L ++ E ++ + Sbjct: 1275 LMNNQDKHIKSINKEFEESKKRDQLEIESLRNQIDEVKESSNIQILNLSQQLEEVKMQEQ 1334 Query: 1466 MHENANHYETMQKE-----SEIE-RVKLIEELNVKITESVSLNKQVAELNKALEEEVAKT 1519 + +T +K+ S++E + + + +L ++I ++ Q+ + L +V + Sbjct: 1335 EKQMLEQKQTEEKQITNLTSQLEVKSQELTQLKIQIQQNSHFEVQLQDAENKLAGQVQQI 1394 Query: 1520 NEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQ-KHVSFASDTKQGRD 1569 +Q +NQ++++ LN +I N Q+ ++ S K V+F+ ++ ++ Sbjct: 1395 ENLQKINQNQQVQLEQLNLQIQNFQDHIQQKSMKYSTSEVNFSEQIEKQQE 1445 Score = 140 bits (338), Expect = 4e-31 Identities = 294/1496 (19%), Positives = 621/1496 (41%), Gaps = 131/1496 (8%) Query: 143 DVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIE-----AKNKATTXXX 197 ++ L N +E +N +Q+ +++ ++ L + + + + ++E ++++ Sbjct: 369 EILVLKNQKQEDENLKQQIQL-IQLEKSDFLSVNQSLRQNQSVLEDQLQILQSQSQENEK 427 Query: 198 XXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEAN 257 + Q + +++ + ++ + D+ Q K IE +D++I L+ N Sbjct: 428 VKRSSAKSDFEREKNELVQNIKNLEQQILVLKKQNFDDLQNN-KKIEEQDLQIQKLK--N 484 Query: 258 KLLEAARFEISLEHSKLAQELE-QXXXXXXXXXXXXXXLAKQSIEPSCEEKTEI------ 310 ++ EA + LE +LE KQ E + +K +I Sbjct: 485 EIREATIKQQKLEQLNGQIQLECDILRSSKRENEQSQEQRKQLYEKAINDKDQIIKQLRD 544 Query: 311 --EEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSP 368 E + T+L KIE++ +L + + T K E++L T + + + + K Sbjct: 545 TLNENQQMFQQLQTQLNIKIEIIANLEKENQNTRKLYEDRLTTSQQDFEQLKTQLKDQIE 604 Query: 369 LISRKSGRNTASKMKSP---WSQLSSETLNQ-DTDKKINKNEIAKLEMVIQSLNKDLVDK 424 +++ + +S M+ Q S + Q D K+ ++ L+ VI+ L Sbjct: 605 QKNKQVEQIQSSFMRDMELLKEQFSLKEAEQLDIQKQADEMRQQLLD-VIEEKQSWLQKY 663 Query: 425 EYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQ 484 E V +E+ + K+ Q +L Q++E L + + NEI Q Sbjct: 664 EKVFAEQQSLSESLGKSQ--KECNSLQEKLFSLQNVEQKQLEDI---LKLKNEIQIASGQ 718 Query: 485 LKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTI 544 Q N ++K N +K++ E +I LN E N+ +I K KL Q Sbjct: 719 QGQASN-QLKQAN-----QKIQELENKIILLNLE----NQKVITEKEEINFKLNQANHEQ 768 Query: 545 DNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIE 604 D K ++ K +L L ++ + E+ K N Q ++ + E +V K Sbjct: 769 DILKKQNEEFK------NQLEQLKNQILQ-EKNKSNEQNQVIQKLQQQAKEEEVLK---- 817 Query: 605 MENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHL 664 ENL +++ ++ + + D +L E + ++ D+SQ++ + S+IK L Sbjct: 818 -ENLM-SKIDSLQQFQQKYHDASLQLEQFNINIQEFQKQIKDLSQIKDE---SQIKINKL 872 Query: 665 -EEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDK 723 E +A KE L LK + + L I + L N ++E + K Sbjct: 873 NSENYEATQQLMKEQEL-NSTLKGEVQHLQLQITQKNGELSSQYELLNNKLKEYEEKEQK 931 Query: 724 LEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENI----ESELSKYKSRIC 779 L +IS+L + +EQ I+ + + +K+ D+ +NI + E + Y+ ++ Sbjct: 932 L----LIQISQLKIQDQEQEQKLIKERDELHSKLINLDISTQNIMSKHQEERNNYERKLF 987 Query: 780 RL-------EESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMD 832 L ++ + D+ + R+ +QL ++KQ SE T++ +E V +L + D Sbjct: 988 DLNNLCNEAKQQNILSTDKLTQVTRELEQLKETNKQKQNQVSELTLKLEE-VTKLKI-TD 1045 Query: 833 HDRVVEKQ-LLEIEHENKELQKKNQILLEEN-QNLQISLSDMQQHYN---ALVEKANRTD 887 ++ E Q ++ + K+ + K I L++N L S S Q N +++ NR Sbjct: 1046 SSKIQELQSQVDFVKQEKDREIKKSIELQKNLDGLIASTSQKDQEINLSKIQIQELNRQI 1105 Query: 888 LAESESTK-YQTQLRDLESNLKRITHEHQTL--IVQKKKEIEDLEIEFNTQIESAIRDKK 944 L +E+ + Y+ Q+ +L+ + ++ E T +++ K ++D I+ T S I ++ Sbjct: 1106 LVSNETIQSYKKQVDNLQESYEKQLSELSTFNEDLKRSKLLDDERIQELTMKTSQIEEQM 1165 Query: 945 VLN-------EKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQ 997 L ++ KN E+ QL Q E + + ++++L + LE +K + +++ Sbjct: 1166 DLRNSQHLQMSEFRKNEEHRFQLLCQQMEIEK--QQFLKDIQDLT-LKLEKCEKELDEEK 1222 Query: 998 TQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKL 1057 Q EQ+ E ++ LLKQ +EE I Q + + KL + Sbjct: 1223 NQFIYQLEQFREEKSQ---LLKQIEEEKSIKENTIFQIQQQFEEQKIQFSLKLNDL---M 1276 Query: 1058 ENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISST 1117 N ++ ++ ++K+ +SK+ + Q+ + +QI E+KE+ +N+ + + Sbjct: 1277 NNQDKHIKSINKEFEESKKRD---QLEIESLRNQIDEVKESSNIQILNLSQQLEEVKMQE 1333 Query: 1118 IEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKII- 1176 E + + +K QE + + + +Q++ +LQ+ K+ Sbjct: 1334 QEKQMLEQKQTEEKQITNLTSQLEVKSQE----LTQLKIQIQQNSHFEVQLQDAENKLAG 1389 Query: 1177 ---QLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGF 1233 Q+E L ++ + V EQ+N L+ + Q + + ++ + +E+ + S ++++ Sbjct: 1390 QVQQIENLQ-KINQNQQVQLEQLN-LQIQNFQDHIQQKSMKYSTSEV--NFSEQIEKQQ- 1444 Query: 1234 EIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTME-QV 1292 E + K +++ E + QK + + + E+L ++Q + + I + Q+ Sbjct: 1445 EFIDKLKSQVSELELNIQKLNLNSTQEKTKLNLEIEKLNQTIQKQQSDYNSSIYKLNCQI 1504 Query: 1293 TSLQNKL---QDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXX 1349 +N++ Q + +++ ++ + +++ S++ K Sbjct: 1505 EIYKNEINVFQSQNNSIQSSKDTFLKEYEKLQEANSKLVLSKSELEMELEILKNQIQHTQ 1564 Query: 1350 XDLRTENQSYKQMQEQSILNINEENAQLKK-SSXXXXXXXXXXXXRVNDAE-AKVLELTH 1407 E + ++Q+ ++ I I E++ +++ + + ND A+ +E Sbjct: 1565 QATILEFEGFRQLNDKRIKEILEKDEKIQDLQNQLHQRDIKMLQFKQNDVGLARQIE-DL 1623 Query: 1408 QLELKDSEIYQKTHEYTI-TLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKM 1466 QL++K+ EI + + + +R + E +QQ + K+I + SE L+ ++ Sbjct: 1624 QLQVKNLEIERNQLQQSYQKFQERIQQLEGQKQQFRDKYKKI---VQQSTSEFLALKSQV 1680 Query: 1467 HENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTAL 1526 A +S I E +N+K+ E ++L Q EL KA E +K E Sbjct: 1681 ENLAKKDANSSIDSSIRYQS--ESINLKMKEELTLKNQ--ELQKAYEFIQSKKQECSVLS 1736 Query: 1527 ENQEIEIVTLNDEI--TNLQNMVRASSSKIQKHVSFASD-TKQGRDEQLDNTMNKE 1579 + E+ L + +LQN + ++ H+ +D KQ L N + E Sbjct: 1737 QQYEVLKQQLEKKAASNSLQNSMEQDGNEELTHLKQENDLLKQKNKTLLQNIVELE 1792 Score = 138 bits (335), Expect = 9e-31 Identities = 221/1123 (19%), Positives = 476/1123 (42%), Gaps = 101/1123 (8%) Query: 235 EKQRLLKDIESKDVRISSLEEANKLLEAARFE---ISLEHSKLAQELEQXXXXXXXXXXX 291 E + +L ++E++ V I+ EE N L A E + ++ + +LEQ Sbjct: 737 ENKIILLNLENQKV-ITEKEEINFKLNQANHEQDILKKQNEEFKNQLEQLKNQILQEKNK 795 Query: 292 XXXLAK--QSIEPSCEEKTEIEEKGSLEIANMTELTKKIE----LLEHLNCQIRQTNKEL 345 + Q ++ +E+ ++E +I ++ + +K LE N I++ K++ Sbjct: 796 SNEQNQVIQKLQQQAKEEEVLKENLMSKIDSLQQFQQKYHDASLQLEQFNINIQEFQKQI 855 Query: 346 ENKLATMGTESKA----VSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDT--- 398 ++ L+ + ES+ ++S + + + + ++ N+ K + QL N + Sbjct: 856 KD-LSQIKDESQIKINKLNSENYEATQQLMKEQELNSTLKGEVQHLQLQITQKNGELSSQ 914 Query: 399 ----DKKINKNEIAKLEMVIQSLNKDLVDKEY---VISEKDTXXXXXXXXXXGKDTLIAQ 451 + K+ + E + +++IQ + D+E +I E+D ++++ Sbjct: 915 YELLNNKLKEYEEKEQKLLIQISQLKIQDQEQEQKLIKERDELHSKLINLDISTQNIMSK 974 Query: 452 LQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQ 511 Q E + D+N + +Q D++ V + +E+LK +Q Sbjct: 975 HQEERNNYER---------KLFDLNNLCNEAKQQNILSTDKLTQVTRE--LEQLKETNKQ 1023 Query: 512 ITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSN-KEIVRLTEELHHLSQK 570 E+ + + K+K K++++Q +D + D K+ + L + L L Sbjct: 1024 KQNQVSELTLKLEEVTKLKITDSSKIQELQSQVDFVKQEKDREIKKSIELQKNLDGLIAS 1083 Query: 571 VAELEEEKGNLQLHLVDYDSGRMIESDV---YKKMIEMENLAETRLKAISLLESQKFDLV 627 ++ ++E ++ + + + ++ ++ YKK ++ NL E+ K +S L + DL Sbjct: 1084 TSQKDQEINLSKIQIQELNRQILVSNETIQSYKKQVD--NLQESYEKQLSELSTFNEDLK 1141 Query: 628 -------QELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQI--DALSASKKEL 678 + + L K ++E+++ D+ Q Q+ K+ Q+ + K++ Sbjct: 1142 RSKLLDDERIQELTMKTSQIEEQM-DLRNSQHLQMSEFRKNEEHRFQLLCQQMEIEKQQF 1200 Query: 679 ALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAK 738 I++L L E+ K+L+ +K + +L+ + +E L ++E+ + K + + Sbjct: 1201 LKDIQDLTLKLEKCE---KELDEEKNQFIYQLEQFREEKSQLLKQIEEEKSIKENTIFQI 1257 Query: 739 INHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERK 798 E+ KIQ ++ + +D +I++I E + K R +LE +E R ++ Sbjct: 1258 QQQFEEQKIQFSLKLNDLMNNQDKHIKSINKEFEESKKR-DQLE-----IESLRNQIDEV 1311 Query: 799 ADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQIL 858 + + + E +QE E L ++ + ++E +++EL + +I Sbjct: 1312 KESSNIQILNLSQQLEEVKMQEQE-KQMLEQKQTEEKQITNLTSQLEVKSQELTQL-KIQ 1369 Query: 859 LEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLI 918 +++N + ++ L D + N L + + + + + Q QL L ++ Q I Sbjct: 1370 IQQNSHFEVQLQDAE---NKLAGQVQQIENLQKINQNQQVQLEQLNLQIQNF----QDHI 1422 Query: 919 VQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMN- 977 QK + E+ F+ QI EK E++ +L++Q+ E + NI+ LN+N Sbjct: 1423 QQKSMKYSTSEVNFSEQI--------------EKQQEFIDKLKSQVSELELNIQKLNLNS 1468 Query: 978 VEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQV 1037 +E K+NLE I+K Q Q Q DY + I KLN ++ EI + N+ Q Sbjct: 1469 TQEKTKLNLE-IEKLNQTIQKQQSDYN----SSIYKLNCQIEIYKNEINVFQSQNNSIQS 1523 Query: 1038 SYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQI--KEL 1095 S + + +YE KL + +KL + E++ + L + QH ++ IL E Q+ K + Sbjct: 1524 SKDTFLKEYE-KLQEANSKLVLSKSELEMELEILKNQIQHTQQATILEFEGFRQLNDKRI 1582 Query: 1096 KETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQ-EEEEFIQER 1154 KE L + I + + I+ + N+V ++ E + Q Sbjct: 1583 KEI-LEKDEKIQDLQNQLHQRDIKMLQFKQNDVGLARQIEDLQLQVKNLEIERNQLQQSY 1641 Query: 1155 SVLQEQSAKLNTELQEC---YTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTEND 1211 QE+ +L + Q+ Y KI+Q T V N + + S + +++ Sbjct: 1642 QKFQERIQQLEGQKQQFRDKYKKIVQQSTSEFLALKSQVENLAKKDANSSIDSSIRYQSE 1701 Query: 1212 NLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQL 1271 ++ + E ++ + Q+ +E + KQ + ++ + +L + ++ + Sbjct: 1702 SINLKMKE-ELTLKNQELQKAYEFIQSKKQECSVLSQQYEVLKQQLEKKAASNSLQNSME 1760 Query: 1272 LDSVQSSTQ-EETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKY 1313 D + T ++ N ++ + T LQN + + E ++ Q+ Y Sbjct: 1761 QDGNEELTHLKQENDLLKQKNKTLLQN-IVELETKQKSQQQMY 1802 Score = 96.3 bits (229), Expect = 6e-18 Identities = 219/1088 (20%), Positives = 425/1088 (39%), Gaps = 129/1088 (11%) Query: 212 EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDI-ESKDVRISSLEEANKLLEAARFEISLE 270 E ++++ + + FI ++++EK +LLK I E K ++ +++ + + E + + SL+ Sbjct: 1212 EKCEKELDEEKNQFIYQLEQFREEKSQLLKQIEEEKSIKENTIFQIQQQFEEQKIQFSLK 1271 Query: 271 HSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIEL 330 + L ++ + IE + E++E +++I N+++ +++++ Sbjct: 1272 LNDLMNNQDKHIKSINKEFEESKKRDQLEIESLRNQIDEVKESSNIQILNLSQQLEEVKM 1331 Query: 331 LEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLS 390 E + Q K+ E K T T V S + I + + +++ ++L+ Sbjct: 1332 QEQEKQMLEQ--KQTEEKQITNLTSQLEVKS-QELTQLKIQIQQNSHFEVQLQDAENKLA 1388 Query: 391 SETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIA 450 + + +KIN+N+ +LE LN + + + I +K Sbjct: 1389 GQVQQIENLQKINQNQQVQLE----QLNLQIQNFQDHIQQKSMKYSTSEVNFSE------ 1438 Query: 451 QLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKS-AE 509 Q+E QQ V ++ ++ Q K +LN EI+ +N I+K +S Sbjct: 1439 --QIEKQQEFIDKLKSQVSELELNIQKLNLNSTQEKTKLNLEIEKLN--QTIQKQQSDYN 1494 Query: 510 EQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKT-IDNFSKVSDSNKEIVRLTEELHHLS 568 I +LN +I+ KN I V + ++ + T + + K+ ++N ++V EL Sbjct: 1495 SSIYKLNCQIE-IYKNEINVFQSQNNSIQSSKDTFLKEYEKLQEANSKLVLSKSELE--- 1550 Query: 569 QKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQ 628 ELE K +Q H ++E + +++ L + R+K I + + DL Sbjct: 1551 ---MELEILKNQIQ-HT---QQATILEFEGFRQ------LNDKRIKEILEKDEKIQDLQN 1597 Query: 629 ELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLD 688 +LH Q+ DI LQ Q V L QI+ +L L ++NL+++ Sbjct: 1598 QLH---QR---------DIKMLQFKQ-----NDVGLARQIE-------DLQLQVKNLEIE 1633 Query: 689 KEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLA-KINHEEQSKI 747 + Q L+ + ++Q + DK +K+ + SE LA K E +K Sbjct: 1634 RNQ-------LQQSYQKFQERIQQLEGQKQQFRDKYKKIVQQSTSEFLALKSQVENLAKK 1686 Query: 748 QTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQ 807 ID+ I+ + ES K K + + + + Y + Q S L Sbjct: 1687 DANSSIDSSIRYQS------ESINLKMKEELTLKNQEL----QKAYEFIQSKKQECSVLS 1736 Query: 808 EKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQI 867 ++ + + +++ N L M+ D ++L ++ EN L++KN+ LL+ L+ Sbjct: 1737 QQYEVLKQ-QLEKKAASNSLQNSMEQDG--NEELTHLKQENDLLKQKNKTLLQNIVELET 1793 Query: 868 SLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKR---ITHEHQTLIVQKKKE 924 QQ Y D +S + Q E N+K+ T + T + K+ Sbjct: 1794 KQKSQQQMYTQSDSIDKYQDTQQSGFSMKQDNYIFTEQNIKQAPIATQQSSTSSTKIKQS 1853 Query: 925 IED---LEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEEL 981 + + I E+ + K++ + Q Q +NN Sbjct: 1854 LVNPYHHYIPLPPTTETQRNNNKIIYSIINNQVPNNDQRYQQKMGIRNNNSPYQQKQSGY 1913 Query: 982 NKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMS 1041 NK+ + K Q + ++ N QK + Q+++ S +S Sbjct: 1914 NKLRGIGQTSNTPKNQGSNTPRSKSQNN---------PQK------IQQELDQLNASGVS 1958 Query: 1042 MVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLT 1101 Y+ K T ++ ++EE +++ KQ NE L+ L E Q+ EL +KL Sbjct: 1959 PTEFYKVKCQLLTEQMAFVQEESEKLKKQ-------NEHLRTLNFEYVKQLNELSASKLR 2011 Query: 1102 FEMNIPKTEGMIISSTIEPMSDD-----ANNVDXXXXXXXXXXXXLKVQE---------- 1146 I T S +I D ANN ++ E Sbjct: 2012 AAEKIIITPEFFESDSINQKVKDFMRKLANNYKLLEKEQTKLVDHCRIMEQDIENYRIKV 2071 Query: 1147 -EEEFIQE--RSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKL 1203 E + I E + Q L L++ K+ L + EL+ + E+I+ L+S + Sbjct: 2072 IEADQITEKLKQTGQHSIDSLVQSLKDSEDKVESLSQHSKELSLELAIKLEKISNLESNI 2131 Query: 1204 EQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSA 1263 + LN E D+ + +L + + + Q E + + + + + EHE R+ Sbjct: 2132 QDLNNEIDDHKNEYQKLMTKYNKMISQNE-EKKNFDHKQIYELQLKCGQLEHESRLLQGT 2190 Query: 1264 FESKYEQL 1271 +++ QL Sbjct: 2191 LQNQNVQL 2198 Score = 69.3 bits (162), Expect = 8e-10 Identities = 254/1378 (18%), Positives = 517/1378 (37%), Gaps = 125/1378 (9%) Query: 90 ISESLANTLKQKEILMEKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSN 149 I++ Q E+L K+K+Y+E ++ I + + + L N Sbjct: 904 ITQKNGELSSQYELLNNKLKEYEEKEQKLLIQISQLKIQDQEQEQKLIKERDELHSKLIN 963 Query: 150 TIKEKDNALSVLQVKMKIMETTILDLQEKINE-KDQIIEAKNKATTXXXXXXXXXXXXXX 208 N +S Q + E + DL NE K Q I + +K T Sbjct: 964 LDISTQNIMSKHQEERNNYERKLFDLNNLCNEAKQQNILSTDKLTQVTRELEQLKETNKQ 1023 Query: 209 XXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIE----SKDVRISSLEEANKLLEAAR 264 ++ ++T E ++ + Q L ++ KD I E K L+ Sbjct: 1024 K--QNQVSELTLKLEEVTKLKITDSSKIQELQSQVDFVKQEKDREIKKSIELQKNLDGLI 1081 Query: 265 FEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTEL 324 S + ++ Q + QS + + E EK E++ E Sbjct: 1082 ASTSQKDQEINLSKIQIQELNRQILVSNETI--QSYKKQVDNLQESYEKQLSELSTFNED 1139 Query: 325 TKKIELLEHLNCQ-IRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMK 383 K+ +LL+ Q + ++E ++ ++ +S K + +M+ Sbjct: 1140 LKRSKLLDDERIQELTMKTSQIEEQMDLRNSQHLQMSEFRKN-----EEHRFQLLCQQME 1194 Query: 384 SPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXX 443 Q + QD K+ K E + + + N+ + E EK Sbjct: 1195 IEKQQFLKDI--QDLTLKLEKCE----KELDEEKNQFIYQLEQFREEKSQLLKQIEEEKS 1248 Query: 444 GKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIE 503 K+ I Q+Q + ++ SL +N++ Q++ + +N E ++ +D +E Sbjct: 1249 IKENTIFQIQQQFEEQKIQFSL--------KLNDLMNNQDKHIKSINKEFEESKKRDQLE 1300 Query: 504 KLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEE 563 ++S QI DE+ ++ I S ++K ++ + K+I LT + Sbjct: 1301 -IESLRNQI----DEVKESSNIQILNLSQQLEEVKMQEQEKQMLEQKQTEEKQITNLTSQ 1355 Query: 564 LHHLSQKVAELE---EEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLE 620 L SQ++ +L+ ++ + ++ L D E+ + ++ ++ENL + + Sbjct: 1356 LEVKSQELTQLKIQIQQNSHFEVQLQD------AENKLAGQVQQIENLQKIN-------Q 1402 Query: 621 SQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELAL 680 +Q+ L Q +Q D ++ K S + +V + +E ID L + EL L Sbjct: 1403 NQQVQLEQLNLQIQNFQDHIQQKSMKYS---TSEVNFSEQIEKQQEFIDKLKSQVSELEL 1459 Query: 681 VIENLKLDKEQLYGTIK-DLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKI 739 I+ L L+ Q + ++E + I + +Y L ++E E + Sbjct: 1460 NIQKLNLNSTQEKTKLNLEIEKLNQTIQKQQSDYNSSIYKLNCQIEIYKNE--INVFQSQ 1517 Query: 740 NHEEQSKIQTQFGIDAKIQERD----LYIENIESELSKYKSRICRLEES-IAVMEDRRYS 794 N+ QS T K+QE + L +E EL K++I +++ I E R Sbjct: 1518 NNSIQSSKDTFLKEYEKLQEANSKLVLSKSELEMELEILKNQIQHTQQATILEFEGFRQL 1577 Query: 795 LERKADQL---GSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKEL 851 +++ ++ +Q+ Q + I+ + L ++ Q+ +E E +L Sbjct: 1578 NDKRIKEILEKDEKIQDLQNQLHQRDIKMLQFKQNDVGLARQIEDLQLQVKNLEIERNQL 1637 Query: 852 QKKNQILLEENQNLQISLSDMQQHYNALVE---------KANRTDLAESE-------STK 895 Q+ Q E Q L+ + Y +V+ K+ +LA+ + S + Sbjct: 1638 QQSYQKFQERIQQLEGQKQQFRDKYKKIVQQSTSEFLALKSQVENLAKKDANSSIDSSIR 1697 Query: 896 YQTQLRDLESNLKRITHEHQTL------IVQKKKEIEDLEIEFNT---QIESAIRDKKVL 946 YQ++ +L+ + +T ++Q L I KK+E L ++ Q+E + Sbjct: 1698 YQSESINLKMK-EELTLKNQELQKAYEFIQSKKQECSVLSQQYEVLKQQLEKKAASNSLQ 1756 Query: 947 NEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQ 1006 N + E +T L+ + K + L N+ EL + Q T+Q Sbjct: 1757 NSMEQDGNEELTHLKQENDLLKQKNKTLLQNIVELETKQKSQQQMYTQSDSIDKYQDTQQ 1816 Query: 1007 YINEINKLNALLKQKD--EEIIALNQKINNAQVSYMSMVSDYESKLA---QFTTKLENME 1061 + + N + +++ + IA Q ++ S+V+ Y + T+ N + Sbjct: 1817 SGFSMKQDNYIFTEQNIKQAPIATQQSSTSSTKIKQSLVNPYHHYIPLPPTTETQRNNNK 1876 Query: 1062 EEMQRVSKQLLDSKQ-HNEELQILVREQDDQIKELKETKLTF---EMNIPKTEGMIISST 1117 ++ Q+ ++ Q + +++ I Q K+ KL N PK +G S+T Sbjct: 1877 IIYSIINNQVPNNDQRYQQKMGIRNNNSPYQQKQSGYNKLRGIGQTSNTPKNQG---SNT 1933 Query: 1118 IEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQ 1177 P S NN V E + + +L EQ A + E ++ + Sbjct: 1934 --PRSKSQNNPQKIQQELDQLNAS-GVSPTEFYKVKCQLLTEQMAFVQEESEKLKKQNEH 1990 Query: 1178 LETLNTELTGHDVVNQEQINQLKSKLEQLNT----ENDNLLSTVAELRSSISSAVDQRGF 1233 L TLN E +N+ ++L++ + + T E+D++ V + +++ + Sbjct: 1991 LRTLNFEYVKQ--LNELSASKLRAAEKIIITPEFFESDSINQKVKDFMRKLAN-----NY 2043 Query: 1234 EIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTME-QV 1292 ++ E + L ++ R+++ + E+L + Q S + E +V Sbjct: 2044 KLLEKEQTKLVDHCRIMEQDIENYRIKVIEADQITEKLKQTGQHSIDSLVQSLKDSEDKV 2103 Query: 1293 TSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDL 1352 SL ++ L EK +++ + I+ L +EI+D K + + Sbjct: 2104 ESLSQHSKELSLELAIKLEKISNLESNIQDLNNEIDDHKNEY--------QKLMTKYNKM 2155 Query: 1353 RTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLE 1410 ++N+ K + I + + QL+ S ++N + K+ +L+ + E Sbjct: 2156 ISQNEEKKNFDHKQIYELQLKCGQLEHESRLLQGTLQNQNVQLNHLDIKIKDLSIENE 2213 Score = 55.2 bits (127), Expect = 1e-05 Identities = 175/927 (18%), Positives = 375/927 (40%), Gaps = 106/927 (11%) Query: 220 KMQENFIAM-EAEWKDEKQ--RLLKDIESKDVRISSLEEANKLLEAARFEISLE--HSKL 274 KMQE M E + +EKQ L +E K ++ L+ ++ + + FE+ L+ +KL Sbjct: 1330 KMQEQEKQMLEQKQTEEKQITNLTSQLEVKSQELTQLKI--QIQQNSHFEVQLQDAENKL 1387 Query: 275 AQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHL 334 A +++Q L + +++ + I++K + +++IE + Sbjct: 1388 AGQVQQIENLQKINQNQQVQLEQLNLQIQ-NFQDHIQQKSMKYSTSEVNFSEQIEKQQEF 1446 Query: 335 NCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETL 394 +++ ELE + + ++S +K + + T K +S ++ S L Sbjct: 1447 IDKLKSQVSELELNIQKLN-----LNSTQEKTKLNLEIEKLNQTIQKQQSDYNS-SIYKL 1500 Query: 395 NQDTDKKINKNEIAKLEMVIQSL--NKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQL 452 N + I KNEI + S+ +KD KEY ++ + I + Sbjct: 1501 NCQIE--IYKNEINVFQSQNNSIQSSKDTFLKEYEKLQEANSKLVLSKSELEMELEILKN 1558 Query: 453 QLEHQQH-----MEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKD----LIE 503 Q++H Q EG ++ E + + K+Q+ Q +IK + K L Sbjct: 1559 QIQHTQQATILEFEGFRQLNDKRIKEILEKDEKIQDLQNQLHQRDIKMLQFKQNDVGLAR 1618 Query: 504 KLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSK-VSDSNKEIVRLTE 562 +++ + Q+ L E + ++ K + + Q Q+ D + K V S E + L Sbjct: 1619 QIEDLQLQVKNLEIERNQLQQSYQKFQERIQQLEGQKQQFRDKYKKIVQQSTSEFLALKS 1678 Query: 563 ELHHLSQKVAE--------LEEEKGNLQLH------------LVDYDSGRMIESDVYKKM 602 ++ +L++K A + E NL++ ++ + E V + Sbjct: 1679 QVENLAKKDANSSIDSSIRYQSESINLKMKEELTLKNQELQKAYEFIQSKKQECSVLSQQ 1738 Query: 603 IE-MENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDK----LADISQLQS----- 652 E ++ E + + SL S + D +EL L+Q+ D ++ K L +I +L++ Sbjct: 1739 YEVLKQQLEKKAASNSLQNSMEQDGNEELTHLKQENDLLKQKNKTLLQNIVELETKQKSQ 1798 Query: 653 DQVCSEIKSV--HLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKL 710 Q+ ++ S+ + + Q S + +N+K + K+ ++N Sbjct: 1799 QQMYTQSDSIDKYQDTQQSGFSMKQDNYIFTEQNIKQAPIATQQSSTSSTKIKQSLVNPY 1858 Query: 711 QNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGI---DAKIQERDL---YI 764 +YI + T + ++ + + I ++ + Q + GI ++ Q++ + Sbjct: 1859 HHYIP--LPPTTETQRNNNKIIYSIINNQVPNNDQRYQQKMGIRNNNSPYQQKQSGYNKL 1916 Query: 765 ENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELV 824 I + K++ S + ++ ++++ DQL + + Y ++ L Sbjct: 1917 RGIGQTSNTPKNQGSNTPRSKS--QNNPQKIQQELDQLNASGVSPTEFYK---VKCQLLT 1971 Query: 825 NRLAVLMDHDRVVEKQLLEIEHEN----KELQKKNQILLEENQNLQISL----SD-MQQH 875 ++A + + ++KQ + N K+L + + L + + I+ SD + Q Sbjct: 1972 EQMAFVQEESEKLKKQNEHLRTLNFEYVKQLNELSASKLRAAEKIIITPEFFESDSINQK 2031 Query: 876 YNALVEK-ANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNT 934 + K AN L E E TK R +E +++ ++ +++ + E L+ Sbjct: 2032 VKDFMRKLANNYKLLEKEQTKLVDHCRIMEQDIEN----YRIKVIEADQITEKLKQTGQH 2087 Query: 935 QIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQ 994 I+S ++ K +K E ++ +L +L I NL N+++LN Sbjct: 2088 SIDSLVQSLKDSEDKVESLSQHSKELSLELAIKLEKISNLESNIQDLN------------ 2135 Query: 995 KQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFT 1054 + D+ +Y + K N ++ Q +E+ +++I Q+ + ++ES+L Q T Sbjct: 2136 ---NEIDDHKNEYQKLMTKYNKMISQNEEKKNFDHKQIYELQLKCGQL--EHESRLLQGT 2190 Query: 1055 TKLENMEEEMQRVSKQLLDSKQHNEEL 1081 L+N ++ + ++ D NE L Sbjct: 2191 --LQNQNVQLNHLDIKIKDLSIENESL 2215 >UniRef50_Q4LE75 Cluster: CENPE variant protein; n=9; Euteleostomi|Rep: CENPE variant protein - Homo sapiens (Human) Length = 2585 Score = 165 bits (400), Expect = 1e-38 Identities = 278/1364 (20%), Positives = 594/1364 (43%), Gaps = 136/1364 (9%) Query: 297 KQSIEPSCEEKTEIEEKGSLEIANM----TELTKKIELLEHLNCQIRQT-----NKELEN 347 K+ +E +EK +++E +LE EL+ K+ELL QI++ +++LEN Sbjct: 526 KEEMELKLKEKNDLDEFEALERKTKKDQENELSSKVELLREKEDQIKKLQEYIDSQKLEN 585 Query: 348 KLATMGTESKAVSSPSKKGSPLISRKS----GRNTASKMKSPWSQLSSETLNQDTDKKIN 403 + +++ P + L ++ + ++ ++S +L + T K Sbjct: 586 IKMDLSYSLESIEDPKQMKQTLFDAETVALDAKRESAFLRSENLELKEKMKELATTYKQM 645 Query: 404 KNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGK--DTLIAQLQLE------ 455 +N+I + +++ K VD E + GK L+ L+LE Sbjct: 646 ENDIQLYQSQLEAKKKMQVDLEKELQSAFNEITKLTSLIDGKVPKDLLCNLELEGKITDL 705 Query: 456 ----HQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNV----KD-LIEKLK 506 +++ E +L ++ + E+L++E+ D+ +++++ KD L ++ Sbjct: 706 QKELNKEVEENEALREEVILLSELKSLPSEVERLRKEIQDKSEELHIITSEKDKLFSEVV 765 Query: 507 SAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQ--KTI--DNFSKVSDSNKEIVRLTE 562 E ++ L +EI ++ +SN+K ++ Q KT+ D K +E R+ + Sbjct: 766 HKESRVQGLLEEIGKTKDDLATTQSNYKSTDQEFQNFKTLHMDFEQKYKMVLEENERMNQ 825 Query: 563 ELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIES--DVYKKMIEMENLAETRLKAISLLE 620 E+ +LS++ + + G L+ L Y + + E +V +++ EME L E S L+ Sbjct: 826 EIVNLSKEAQKFDSSLGALKTEL-SYKTQELQEKTREVQERLNEMEQLKEQLENRDSTLQ 884 Query: 621 SQKFDLVQELHILQQKYDEVE---DKLADISQLQSD-QVCSEIKSVHLEEQIDALSASKK 676 + + + LQQ +EV+ + D+ QLQ Q+ + + + ++ +++ Sbjct: 885 TVEREKTLITEKLQQTLEEVKTLTQEKDDLKQLQESLQIERDQLKSDIHDTVNMNIDTQE 944 Query: 677 ELALVIENLKLDKEQLYGTIKDLENDK-------EDIMNKLQNYIQENMDLTDKLEKMSA 729 +L +E+LK +E + T+K +++ E+ + ++ Q+ M DK + + A Sbjct: 945 QLRNALESLKQHQETI-NTLKSKISEEVSRNLHMEENTGETKDEFQQKMVGIDKKQDLEA 1003 Query: 730 EKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVME 789 + L A + E I+ Q I + IQE++ + +ES +++ + L+E+I + Sbjct: 1004 KNTQTLTADVKDNEI--IEQQRKIFSLIQEKNELQQMLESVIAEKEQLKTDLKENIEMTI 1061 Query: 790 DRRYSLERKADQLGSYLQEKQKAYSEYTIQEDEL---VNRLAVLMDH-----DRVVEKQ- 840 + + L D+L + + + +E EL +RLA + + ++ EKQ Sbjct: 1062 ENQEELRLLGDELKKQQEIVAQEKNHAIKKEGELSRTCDRLAEVEEKLKEKSQQLQEKQQ 1121 Query: 841 -LLEIEHENKELQKK-NQI--LLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKY 896 LL ++ E E+QKK N+I L E +N +++L M+ L +K N TK Sbjct: 1122 QLLNVQEEMSEMQKKINEIENLKNELKNKELTLEHMETERLELAQKLNENYEEVKSITKE 1181 Query: 897 QTQLRDLESN-------LKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEK 949 + L++L+ + L+ E + +Q K+E++ I E+ ++ ++EK Sbjct: 1182 RKVLKELQKSFETERDHLRGYIREIEATGLQTKEELKIAHIHLKEHQETIDELRRSVSEK 1241 Query: 950 YEK--NIEYVTQLEAQLQE---YKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYT 1004 + N + + + +LQE + + L NV+E+++ + + + +Q+ + D T Sbjct: 1242 TAQIINTQDLEKSHTKLQEEIPVLHEEQELLPNVKEVSETQETMNELELLTEQSTTKDST 1301 Query: 1005 EQYINEINKL--NALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEE 1062 E+ +L N ++ EEI +L ++ +N + ++ ++ L ++E Sbjct: 1302 TLARIEMERLRLNEKFQESQEEIKSLTKERDNLKTIKEALEVKHDQLKEHIRETLAKIQE 1361 Query: 1063 EMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMS 1122 + +Q L+ K+ + E +V E + Q K L E+ E + +S ++ Sbjct: 1362 SQSK-QEQSLNMKEKDNETTKIVSEME-QFKPKDSALLRIEI-----EMLGLSKRLQESH 1414 Query: 1123 DDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLN 1182 D+ +V +E+++ + + VLQ +S +L ++E K LET Sbjct: 1415 DEMKSV---------------AKEKDDLQRLQEVLQSESDQLKENIKEIVAK--HLETEE 1457 Query: 1183 TELTGHDVVNQEQ--INQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWK 1240 H + +++ IN+L+ L + TE +ST+ + +I+ + + EI E + Sbjct: 1458 ELKVAHCCLKEQEETINELRVNLSEKETE----ISTIQKQLEAINDKLQNKIQEIYEKEE 1513 Query: 1241 QHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQ 1300 Q ++ ++ Q+ +EL+ Q + L S++S E TN++ E +Q ++ Sbjct: 1514 QFNIKQISEVQEKVNELK-QFKEHRKAKDSALQSIESKMLELTNRL--QESQEEIQIMIK 1570 Query: 1301 DKEEHLRNLQEKYADVINQI-----EILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTE 1355 +KEE ++ +QE +Q+ EI+ E ++ + ++ Sbjct: 1571 EKEE-MKRVQEALQIERDQLKENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEHL 1629 Query: 1356 NQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSE 1415 + + + Q+ ++ NI EN +L + +D + + L+++ + Sbjct: 1630 KEQF-ETQKLNLENIETENIRLTQILHENLEEMRSVTKERDDLRS----VEETLKVERDQ 1684 Query: 1416 IYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDL---TYEKESELAILRLKMHENANH 1472 + + E ++ +E + V L E+++ I+ L EK +E++ M ++ H Sbjct: 1685 LKENLRETITRDLEKQEELKIVHMHLKEHQETIDKLRGIVSEKTNEIS----NMQKDLEH 1740 Query: 1473 YETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIE 1532 K ++ K+ EEL + + + +L + E+ K + MQ LEN + Sbjct: 1741 SNDALKAQDL---KIQEELRIAHMHLKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAK 1797 Query: 1533 IVTLNDEI-TNLQNMV--RASSSKIQKHVSFASD-TKQGRDEQL 1572 + E+ N ++ + ++ QK VS KQ +D+ L Sbjct: 1798 LQEKIQELKANEHQLITLKKDVNETQKKVSEMEQLKKQIKDQSL 1841 Score = 132 bits (320), Expect = 6e-29 Identities = 318/1563 (20%), Positives = 670/1563 (42%), Gaps = 193/1563 (12%) Query: 91 SESLANTLKQKEILMEKIKQYKE-LSKRSSTT-IVRXXXXXXXXXXXXXXXQLGDVTHLS 148 ++ L ++ + + +++Q KE L R ST V ++ +T Sbjct: 852 TQELQEKTREVQERLNEMEQLKEQLENRDSTLQTVEREKTLITEKLQQTLEEVKTLTQEK 911 Query: 149 NTIKEKDNALSVL--QVKMKIMETTIL--DLQEKINEKDQIIEAKNKATTXXXXXXXXXX 204 + +K+ +L + Q+K I +T + D QE++ + ++ + Sbjct: 912 DDLKQLQESLQIERDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQETINTLKSKISEEV 971 Query: 205 XXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLE-EANKLLEAA 263 E+T + + Q+ + + D+KQ D+E+K+ + + + + N+++E Sbjct: 972 SRNLHMEENTGETKDEFQQKMVGI-----DKKQ----DLEAKNTQTLTADVKDNEIIEQQ 1022 Query: 264 RFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEI-----EEKGSLEI 318 R SL K EL+Q K++IE + E + E+ E K EI Sbjct: 1023 RKIFSLIQEK--NELQQMLESVIAEKEQLKTDLKENIEMTIENQEELRLLGDELKKQQEI 1080 Query: 319 ANMT---------ELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPL 369 EL++ + L + ++++ +++L+ K + + +S KK + + Sbjct: 1081 VAQEKNHAIKKEGELSRTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEI 1140 Query: 370 ISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKN-----EIAKLEMVIQSLNKDL-VD 423 + K N + + +E L + +K+N+N I K V++ L K + Sbjct: 1141 ENLK---NELKNKELTLEHMETERL--ELAQKLNENYEEVKSITKERKVLKELQKSFETE 1195 Query: 424 KEYVISEKDTXXXXXXXXXXGKDTL-IAQLQL-EHQQHM-EGPSLIHVGT----NTEDVN 476 ++++ + K+ L IA + L EHQ+ + E + T NT+D+ Sbjct: 1196 RDHL---RGYIREIEATGLQTKEELKIAHIHLKEHQETIDELRRSVSEKTAQIINTQDLE 1252 Query: 477 EI-AKVQEQL-----KQELNDEIKDVN-VKDLIEKLKSAEEQITQLNDEIDAANKNMIKV 529 + K+QE++ +QEL +K+V+ ++ + +L+ EQ T D A M ++ Sbjct: 1253 KSHTKLQEEIPVLHEEQELLPNVKEVSETQETMNELELLTEQSTT-KDSTTLARIEMERL 1311 Query: 530 KSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELH-----HLSQKVAELEEEKGNLQLH 584 + N K + + Q+ I + +K D+ K I E H H+ + +A+++E + + Sbjct: 1312 RLNEKFQ--ESQEEIKSLTKERDNLKTIKEALEVKHDQLKEHIRETLAKIQESQSKQEQS 1369 Query: 585 LVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDL---VQELHILQQKYDEVE 641 L + + +++ K + EME + + A+ +E + L +QE H + + + Sbjct: 1370 L----NMKEKDNETTKIVSEMEQF-KPKDSALLRIEIEMLGLSKRLQESHDEMKSVAKEK 1424 Query: 642 D---KLADISQLQSDQVCSEIKSV---HLE--EQIDALSASKKELALVIENLKLDKEQLY 693 D +L ++ Q +SDQ+ IK + HLE E++ KE I L+++ + Sbjct: 1425 DDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQEETINELRVNLSEKE 1484 Query: 694 GTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGI 753 I ++ E I +KLQN IQE + +K E+ + ++ISE+ K+N +Q K + Sbjct: 1485 TEISTIQKQLEAINDKLQNKIQE---IYEKEEQFNIKQISEVQEKVNELKQFKEHRK--- 1538 Query: 754 DAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAY 813 +D +++IES++ + +R+ +E I +M + ++R + L Q ++ Sbjct: 1539 -----AKDSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEAL----QIERDQL 1589 Query: 814 SEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQI--LLEENQNLQISLSD 871 E T E+V + M + E Q L++ N+ +K +I L E+ + +++L + Sbjct: 1590 KENT---KEIVAK----MKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQKLNLEN 1642 Query: 872 MQQHYNALVEKANRTDLAESES-TKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEI 930 ++ N + + +L E S TK + LR +E LK V++ + E+L Sbjct: 1643 IETE-NIRLTQILHENLEEMRSVTKERDDLRSVEETLK----------VERDQLKENLRE 1691 Query: 931 EFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELID 990 +E + K+++ +++ E + +L + E N I N+ ++E N L+ D Sbjct: 1692 TITRDLEKQ-EELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDA-LKAQD 1749 Query: 991 KHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKL 1050 +Q++ + + ++ I+KL ++ +K + K++N Q D E+ Sbjct: 1750 LKIQEELRIAHMHLKEQQETIDKLRGIVSEKTD-------KLSNMQ-------KDLENSN 1795 Query: 1051 AQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTE 1110 A KL+ +E++ QL+ K+ E Q V E + K++K+ LT ++ + E Sbjct: 1796 A----KLQEKIQELKANEHQLITLKKDVNETQKKVSEMEQLKKQIKDQSLT--LSKLEIE 1849 Query: 1111 GMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEE--EFIQE---RSVLQEQSAK-- 1163 + ++ + ++ +V LK++ ++ E +QE R + +Q K Sbjct: 1850 NLNLAQKLHENLEEMKSVMKERDNLRRVEETLKLERDQLKESLQETKARDLEIQQELKTA 1909 Query: 1164 --LNTELQECYTKI--------IQLETLNTEL-TGHDVVNQE---QINQLKSKLEQLNTE 1209 L+ E +E K+ IQ+ + +L D + ++ Q +Q+K + L+ Sbjct: 1910 RMLSKEHKETVDKLREKISEKTIQISDIQKDLDKSKDELQKKQDRQNHQVKPEKRLLSDG 1969 Query: 1210 NDNLLSTVAELRSSISSAVDQRGFEIAELWK--QHLA---QREADFQKTEHELRVQ---- 1260 +L ++ E S I + +R E+ + ++ L+ ++E +FQK E +RV+ Sbjct: 1970 QQHLTESLREKCSRIKELL-KRYSEMDDHYECLNRLSLDLEKEIEFQK-ELSMRVKANLS 2027 Query: 1261 LSAFESKY-EQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKE-EHLRNLQEKYADVIN 1318 L ++K+ E+L + Q + E + ++ V S K+++++ E + + + D + Sbjct: 2028 LPYLQTKHIEKLFTANQRCSMEFHRIMKKLKYVLSYVTKIKEEQHESINKFEMDFIDEVE 2087 Query: 1319 QIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLK 1378 + + L +I+ + DL E + K E +I E Q+ Sbjct: 2088 KQKELLIKIQHLQQDCDVPSRELRDLKLNQNMDLHIE-EILKDFSESEFPSIKTEFQQVL 2146 Query: 1379 KSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVR 1438 + D E +L + ++ ++ I Q + + N+ + Sbjct: 2147 SNRKEMTQFLEEWLNTRFDIE----KLKNGIQKENDRICQVNNFF-------NNRIIAIM 2195 Query: 1439 QQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKE-SEIERVK--LIEELNVKI 1495 + E+E+R ++ E E +L L+ K + +Y+T++ + +V + N + Sbjct: 2196 NESTEFEERSATISKEWEQDLKSLKEKNEKLFKNYQTLKTSLASGAQVNPTTQDNKNPHV 2255 Query: 1496 TESVS--LNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSK 1553 T + +++ EL +L E ++ + + E+ ND I LQ V S+ Sbjct: 2256 TSRATQLTTEKIRELENSLHEAKESAMHKESKIIKMQKELEVTNDIIAKLQAKVHESNKC 2315 Query: 1554 IQK 1556 ++K Sbjct: 2316 LEK 2318 Score = 128 bits (308), Expect = 2e-27 Identities = 257/1487 (17%), Positives = 615/1487 (41%), Gaps = 112/1487 (7%) Query: 93 SLANTLKQKEILMEKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIK 152 S L++KE ++K+++Y + K + + L D ++ K Sbjct: 559 SKVELLREKEDQIKKLQEYIDSQKLENIKMDLSYSLESIEDPKQMKQTLFDAETVALDAK 618 Query: 153 EKDNALSV----LQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXX 208 + L L+ KMK + TT ++ I +EAK K Sbjct: 619 RESAFLRSENLELKEKMKELATTYKQMENDIQLYQSQLEAKKKMQVDLEKELQSAFNEIT 678 Query: 209 XXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEIS 268 ++ K + +E + D ++ L K++E + +L E LL + + Sbjct: 679 KLTSLIDGKVPKDLLCNLELEGKITDLQKELNKEVEENE----ALREEVILLSELK-SLP 733 Query: 269 LEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLE------IANMT 322 E +L +E++ L + + + +EE G + +N Sbjct: 734 SEVERLRKEIQDKSEELHIITSEKDKLFSEVVHKESRVQGLLEEIGKTKDDLATTQSNYK 793 Query: 323 ELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKK-GSPLISRKSGRNTASK 381 ++ + + L+ Q K + + M E +S ++K S L + K+ + ++ Sbjct: 794 STDQEFQNFKTLHMDFEQKYKMVLEENERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQ 853 Query: 382 MKSPWSQLSSETLNQ-DTDKKINKNEIAKLE-------MVIQSLNKDLVDKEYVISEKDT 433 ++ E LN+ + K+ +N + L+ ++ + L + L + + + EKD Sbjct: 854 ELQEKTREVQERLNEMEQLKEQLENRDSTLQTVEREKTLITEKLQQTLEEVKTLTQEKDD 913 Query: 434 XXXXXXXXXXGKDTL------IAQLQLEHQQHMEGPSLIHVGTNTEDVNEI-AKVQEQLK 486 +D L + ++ Q+ + +L + + E +N + +K+ E++ Sbjct: 914 LKQLQESLQIERDQLKSDIHDTVNMNIDTQEQLRN-ALESLKQHQETINTLKSKISEEVS 972 Query: 487 QELNDEIKDVNVKDL-------IEKLKSAEEQITQL-------NDEIDAANKNMIKVKSN 532 + L+ E KD I+K + E + TQ N+ I+ K ++ Sbjct: 973 RNLHMEENTGETKDEFQQKMVGIDKKQDLEAKNTQTLTADVKDNEIIEQQRKIFSLIQEK 1032 Query: 533 HKLKLKQMQKTIDNFSKVSDSNKEIVRLT----EELHHLSQKVAELEEEKGNLQLHLVDY 588 ++L+ + ++ I ++ KE + +T EEL L ++ + +E + H + Sbjct: 1033 NELQ-QMLESVIAEKEQLKTDLKENIEMTIENQEELRLLGDELKKQQEIVAQEKNHAIKK 1091 Query: 589 DSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVE------- 641 + G + S ++ E+E + + + + + Q ++ +E+ +Q+K +E+E Sbjct: 1092 E-GEL--SRTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEIENLKNELK 1148 Query: 642 DKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLE- 700 +K + ++++++ K E++ +++ +K L + ++ + +++ L G I+++E Sbjct: 1149 NKELTLEHMETERLELAQKLNENYEEVKSITKERKVLKELQKSFETERDHLRGYIREIEA 1208 Query: 701 ---NDKEDIMNKLQN-YIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAK 756 KE++ K+ + +++E+ + D+L + +EK +++ IN ++ K T K Sbjct: 1209 TGLQTKEEL--KIAHIHLKEHQETIDELRRSVSEKTAQI---INTQDLEKSHT------K 1257 Query: 757 IQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEY 816 +QE ++ + + E EL + +E++ +E K + ++ ++ +E Sbjct: 1258 LQE-EIPVLHEEQELLPNVKEVSETQETMNELELLTEQSTTKDSTTLARIEMERLRLNEK 1316 Query: 817 TIQEDELVNRLAVLMDHDRVVEKQLLEIEHEN-KELQKKNQILLEENQNLQ---ISLSDM 872 + E + L D+ + + K+ LE++H+ KE ++ ++E+Q+ Q +++ + Sbjct: 1317 FQESQEEIKSLTKERDNLKTI-KEALEVKHDQLKEHIRETLAKIQESQSKQEQSLNMKEK 1375 Query: 873 QQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEF 932 +V + + +S + + ++ L L+ +H+ + ++K +++ L+ Sbjct: 1376 DNETTKIVSEMEQFKPKDSALLRIEIEMLGLSKRLQE-SHDEMKSVAKEKDDLQRLQEVL 1434 Query: 933 NTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKH 992 ++ + + K + K+ + E + L+E + I L +N+ E + + I K Sbjct: 1435 QSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQEETINELRVNLSE-KETEISTIQKQ 1493 Query: 993 VQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQ 1052 ++ + + ++ + + N + +E + ++ + + S + ESK+ + Sbjct: 1494 LEAINDKLQNKIQEIYEKEEQFNIKQISEVQEKVNELKQFKEHRKAKDSALQSIESKMLE 1553 Query: 1053 FTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKE-LKETKLTFEMNIPKTEG 1111 T +L+ +EE+Q + K+ + K+ E LQI + DQ+KE KE + + K Sbjct: 1554 LTNRLQESQEEIQIMIKEKEEMKRVQEALQI----ERDQLKENTKEIVAKMKESQEKEYQ 1609 Query: 1112 MIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQEC 1171 + + + + ++ L+ E E I+ +L E ++ + +E Sbjct: 1610 FLKMTAVNETQEKMCEIEHLKEQFETQKLNLE-NIETENIRLTQILHENLEEMRSVTKER 1668 Query: 1172 YTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNL---LSTVAELRSSISSAV 1228 ETL E +E I + K E+L + +L T+ +LR +S Sbjct: 1669 DDLRSVEETLKVERDQLKENLRETITRDLEKQEELKIVHMHLKEHQETIDKLRGIVSEKT 1728 Query: 1229 DQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVT 1288 ++ +L + A + D K + ELR+ + + ++ +D ++ E+T+K+ Sbjct: 1729 NEISNMQKDLEHSNDALKAQDL-KIQEELRIAHMHLKEQ-QETIDKLRGIVSEKTDKLSN 1786 Query: 1289 MEQVTSLQN-KLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXX 1347 M++ N KLQ+K + L+ + + + + + ++ + + Sbjct: 1787 MQKDLENSNAKLQEKIQELKANEHQLITLKKDVNETQKKVSEMEQLKKQIKDQSLTLSKL 1846 Query: 1348 XXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTH 1407 +L + ++ ++E ++ +E L++ + + +A+ LE+ Sbjct: 1847 EIENLNLAQKLHENLEEMK--SVMKERDNLRRVEETLKLERDQLKESLQETKARDLEI-- 1902 Query: 1408 QLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMH 1467 Q ELK + + K H+ T+ + +R+++ E +I D+ + + L+ K Sbjct: 1903 QQELKTARMLSKEHKETV---------DKLREKISEKTIQISDIQKDLDKSKDELQ-KKQ 1952 Query: 1468 ENANHYETMQKESEIE-RVKLIEELNVKITESVSLNKQVAELNKALE 1513 + NH +K + + L E L K + L K+ +E++ E Sbjct: 1953 DRQNHQVKPEKRLLSDGQQHLTESLREKCSRIKELLKRYSEMDDHYE 1999 Score = 106 bits (254), Expect = 6e-21 Identities = 192/973 (19%), Positives = 428/973 (43%), Gaps = 72/973 (7%) Query: 140 QLGDVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXX 199 Q+ +V N +K+ ++ +E+ +L+L ++ E + I+ K Sbjct: 1519 QISEVQEKVNELKQFKEHRKAKDSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRV 1578 Query: 200 XXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKL 259 E+TK+ + KM+E+ E E++ K + + + K I L+E + Sbjct: 1579 QEALQIERDQLKENTKEIVAKMKES---QEKEYQFLKMTAVNETQEKMCEIEHLKEQFET 1635 Query: 260 LEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCE-EKTEIEEKGSLEI 318 + I E+ +L Q L + L +S+E + + E+ +++E I Sbjct: 1636 QKLNLENIETENIRLTQILHENLEEMRSVTKERDDL--RSVEETLKVERDQLKENLRETI 1693 Query: 319 ANMTELTKKIELL-----EHLNC--QIRQTNKELENKLATMGTESKAVSSPSKKGSPLIS 371 E ++++++ EH ++R E N+++ M + + S+ + K L Sbjct: 1694 TRDLEKQEELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEH-SNDALKAQDLKI 1752 Query: 372 RKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEK 431 ++ R +K Q + + L +K +K ++ ++ +++ N L +K + Sbjct: 1753 QEELRIAHMHLKE--QQETIDKLRGIVSEKTDK--LSNMQKDLENSNAKLQEKIQELKAN 1808 Query: 432 DTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELND 491 + +++++ + ++ ++ SL E++N K+ E L +E+ Sbjct: 1809 EHQLITLKKDVNETQKKVSEME-QLKKQIKDQSLTLSKLEIENLNLAQKLHENL-EEMKS 1866 Query: 492 EIKDV-NVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNF-SK 549 +K+ N++ + E LK +Q+ + E A + + + ++ K+ ++T+D K Sbjct: 1867 VMKERDNLRRVEETLKLERDQLKESLQETKARDLEIQQELKTARMLSKEHKETVDKLREK 1926 Query: 550 VSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLA 609 +S+ +I + ++L ++ ++K + Q H V + R++ SD + + E Sbjct: 1927 ISEKTIQISDIQKDLDKSKDEL----QKKQDRQNHQVKPEK-RLL-SDGQQHLTESLREK 1980 Query: 610 ETRLKAISLLESQKFDLVQELHILQQKYD-EVEDKLADISQLQSDQVCSEIKSVHLEEQI 668 +R+K + S+ D + L+ L + E+E + +++++ +++ H+E+ Sbjct: 1981 CSRIKELLKRYSEMDDHYECLNRLSLDLEKEIEFQKELSMRVKANLSLPYLQTKHIEKLF 2040 Query: 669 DALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMS 728 A E +++ LK + + ++ ++ + +NK + MD D++EK Sbjct: 2041 TANQRCSMEFHRIMKKLKY----VLSYVTKIKEEQHESINKFE------MDFIDEVEKQK 2090 Query: 729 AEKISELLAKINHEEQS-KIQTQFGIDAKI-QERDLYIENIESELSKYKSRICRLEESIA 786 ELL KI H +Q + ++ D K+ Q DL+IE I + S+ + + E Sbjct: 2091 -----ELLIKIQHLQQDCDVPSRELRDLKLNQNMDLHIEEILKDFSESEFPSIKTEFQ-Q 2144 Query: 787 VMEDRRYSLERKADQLGSYLQ-EK-----QKAYSEYTIQEDELVNRLAVLMDHDRVVEKQ 840 V+ +R+ + + L + EK QK + NR+ +M+ E++ Sbjct: 2145 VLSNRKEMTQFLEEWLNTRFDIEKLKNGIQKENDRICQVNNFFNNRIIAIMNESTEFEER 2204 Query: 841 LLEI----EHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKY 896 I E + K L++KN+ L + Q L+ SL+ Q N + N+ S +T+ Sbjct: 2205 SATISKEWEQDLKSLKEKNEKLFKNYQTLKTSLASGAQ-VNPTTQD-NKNPHVTSRATQL 2262 Query: 897 QTQ-LRDLESNL---KRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEK 952 T+ +R+LE++L K ++ I++ +KE+E + + ++++ + + EK ++ Sbjct: 2263 TTEKIRELENSLHEAKESAMHKESKIIKMQKELE-VTNDIIAKLQAKVHESNKCLEKTKE 2321 Query: 953 NIEYVTQLEAQ-LQEYKNNIENLNMNVE--ELNKM-NLELIDKHVQKQQTQSPDYTEQYI 1008 I+ + A + YK IE+L M + +L KM N + +K + + + +Y ++ I Sbjct: 2322 TIQVLQDKVALGAKPYKEEIEDLKMKLVKIDLEKMKNAKEFEKEISATKA-TVEYQKEVI 2380 Query: 1009 NEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVS 1068 + + N Q+ ++ +++ + Q S + S + Q TK ++ E R+ Sbjct: 2381 RLLRE-NLRRSQQAQDTSVISEH-TDPQPSNKPLTCGGGSGIVQ-NTKALILKSEHIRLE 2437 Query: 1069 KQLLDSKQHNEEL 1081 K++ KQ NE+L Sbjct: 2438 KEISKLKQQNEQL 2450 Score = 82.6 bits (195), Expect = 8e-14 Identities = 166/855 (19%), Positives = 356/855 (41%), Gaps = 81/855 (9%) Query: 750 QFGIDAKIQERDLYIENIESE---LSKYKSRICRLEESI--AVMEDRRYSLERKADQLGS 804 QF AK + Y+ + ++ L +Y+ I L++ + +E R ++E+ DQL Sbjct: 326 QFASTAKYMKNTPYVNEVSTDEALLKRYRKEIMDLKKQLEEVSLETRAQAMEK--DQLAQ 383 Query: 805 YLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQN 864 L+EK +Q +++ N +L+ + +Q L+ + + + +I +N N Sbjct: 384 LLEEKDLLQK---VQNEKIENLTRMLVTSSSLTLQQELKAKRKRRVTWCLGKINKMKNSN 440 Query: 865 LQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKE 924 S++ + K + L E + + D+ SN E + K Sbjct: 441 -YADQSNIPTNITTKTHKLSINLLREIDESVCSES--DVFSNTLDTLSEIEWNPATKLLN 497 Query: 925 IEDLEIEFNT---QIESAIRD-KKVLNEKYEKNIEY-----VTQLEAQLQEYKNNIEN-L 974 E++E E N+ ++ + D +++ EK E ++ + + EA ++ K + EN L Sbjct: 498 QENIESELNSLRADYDNLVLDYEQLRTEKEEMELKLKEKNDLDEFEALERKTKKDQENEL 557 Query: 975 NMNVEELNKM--NLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQK--DEEIIALNQ 1030 + VE L + ++ + +++ Q+ ++ Y E + +KQ D E +AL+ Sbjct: 558 SSKVELLREKEDQIKKLQEYIDSQKLENIKMDLSYSLESIEDPKQMKQTLFDAETVALDA 617 Query: 1031 KINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDD 1090 K +A + ++ + + K+ + T + ME ++Q QL K+ +L+ +E Sbjct: 618 KRESAFLRSENL--ELKEKMKELATTYKQMENDIQLYQSQLEAKKKMQVDLE---KELQS 672 Query: 1091 QIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEF 1150 E+ TKLT +G + + + + D ++EE Sbjct: 673 AFNEI--TKLT-----SLIDGKVPKDLLCNLELEGKITDLQKELNKEVEENEALREEVIL 725 Query: 1151 IQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQ-----INQLKSKLEQ 1205 + E L + +L E+Q+ ++ + + T + +VV++E + ++ + Sbjct: 726 LSELKSLPSEVERLRKEIQD-KSEELHIITSEKDKLFSEVVHKESRVQGLLEEIGKTKDD 784 Query: 1206 LNTENDNLLSTVAELRSSISSAVD-QRGFEIAELWKQHLAQREADFQKTEHELRVQLSAF 1264 L T N ST E ++ + +D ++ +++ + + Q + K + L A Sbjct: 785 LATTQSNYKSTDQEFQNFKTLHMDFEQKYKMVLEENERMNQEIVNLSKEAQKFDSSLGAL 844 Query: 1265 ESKYEQLLDSVQSSTQEETNKIVTMEQV-TSLQNK---LQDKEEHLRNLQEKYADVINQI 1320 +++ +Q T+E ++ MEQ+ L+N+ LQ E + EK + ++ Sbjct: 845 KTELSYKTQELQEKTREVQERLNEMEQLKEQLENRDSTLQTVEREKTLITEKLQQTLEEV 904 Query: 1321 EILRSEIED----------EKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQ-SIL- 1368 + L E +D E+ LR +S KQ QE + L Sbjct: 905 KTLTQEKDDLKQLQESLQIERDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQETINTLK 964 Query: 1369 -NINEE---NAQLKKSSXXXXXXXXXXXXRVN---DAEAKVLELTHQLELKDSEIYQKTH 1421 I+EE N +++++ ++ D EAK + T ++KD+EI ++ Sbjct: 965 SKISEEVSRNLHMEENTGETKDEFQQKMVGIDKKQDLEAKNTQ-TLTADVKDNEIIEQQR 1023 Query: 1422 EYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESE 1481 + + ++N+ + + + E E+ DL ++ E+ I EN + E + Sbjct: 1024 KIFSLIQEKNELQQMLESVIAEKEQLKTDL--KENIEMTI------ENQEELRLLGDELK 1075 Query: 1482 IERVKLIEELNVKITESVSLNK---QVAELNKALEEEVAKTNEMQTALENQEIEIVTLND 1538 ++ + +E N I + L++ ++AE+ + L+E+ + E Q L N + E+ + Sbjct: 1076 KQQEIVAQEKNHAIKKEGELSRTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQK 1135 Query: 1539 EITNLQNMVRASSSK 1553 +I ++N+ +K Sbjct: 1136 KINEIENLKNELKNK 1150 Score = 72.1 bits (169), Expect = 1e-10 Identities = 204/1035 (19%), Positives = 425/1035 (41%), Gaps = 122/1035 (11%) Query: 168 METTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIA 227 +E L L EK E + I++ K E ++ + K+QE+ Sbjct: 1306 IEMERLRLNEKFQESQEEIKSLTKERDNLKTIKEALEVKHDQLKEHIRETLAKIQES--- 1362 Query: 228 MEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXX 287 + K E+ +K+ +++ +I S E K ++A I +E L++ L++ Sbjct: 1363 ---QSKQEQSLNMKEKDNETTKIVSEMEQFKPKDSALLRIEIEMLGLSKRLQESHDEMKS 1419 Query: 288 XXXXXXXLAK-----QSIEPSCEEKTE------IEEKGSLEIANM-------------TE 323 L + QS +E + +E + L++A+ Sbjct: 1420 VAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQEETINELRVN 1479 Query: 324 LTKKIELLEHLNCQIRQTNKELENKLATMGTES-----KAVSSPSKKGSPLISRKSGRNT 378 L++K + + Q+ N +L+NK+ + + K +S +K + L K R Sbjct: 1480 LSEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQFNIKQISEVQEKVNELKQFKEHRKA 1539 Query: 379 A-SKMKSPWSQLSSETLN-QDTDKKIN-----KNEIAKLEMVIQSLNKDLVD--KEYVIS 429 S ++S S++ T Q++ ++I K E+ +++ +Q L + KE V Sbjct: 1540 KDSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQIERDQLKENTKEIVAK 1599 Query: 430 EKDTXXXXXXXX--XXGKDTLIAQLQLEH-QQHMEGPSLIHVGTNTEDVNEIAKVQEQLK 486 K++ +T ++EH ++ E L TE++ + E L+ Sbjct: 1600 MKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQKLNLENIETENIRLTQILHENLE 1659 Query: 487 QELNDEIKDVNVKDLIEKLKSAEEQITQ-LNDEIDAANKNMIKVKSNHKLKLKQMQKTID 545 + + + +++ + E LK +Q+ + L + I + ++K H + LK+ Q+TID Sbjct: 1660 EMRSVTKERDDLRSVEETLKVERDQLKENLRETITRDLEKQEELKIVH-MHLKEHQETID 1718 Query: 546 NFSK-VSDSNKEIVRLTEELHH----LSQKVAELEEEKGNLQLHLVDY----DSGRMIES 596 VS+ EI + ++L H L + +++EE +HL + D R I S Sbjct: 1719 KLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQQETIDKLRGIVS 1778 Query: 597 DVYKKMIEME-NLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQS--- 652 + K+ M+ +L + K ++ K + +L L++ +E + K++++ QL+ Sbjct: 1779 EKTDKLSNMQKDLENSNAKLQEKIQELKAN-EHQLITLKKDVNETQKKVSEMEQLKKQIK 1837 Query: 653 DQVCS----EIKSVHL----EEQIDALSASKKE---LALVIENLKLDKEQLYGTIKDLEN 701 DQ + EI++++L E ++ + + KE L V E LKL+++QL ++++ + Sbjct: 1838 DQSLTLSKLEIENLNLAQKLHENLEEMKSVMKERDNLRRVEETLKLERDQLKESLQETKA 1897 Query: 702 DKEDIMNKLQN---YIQENMDLTDKLEKMSAEK---ISELLAKINH--EEQSKIQTQFGI 753 +I +L+ +E+ + DKL + +EK IS++ ++ +E K Q + Sbjct: 1898 RDLEIQQELKTARMLSKEHKETVDKLREKISEKTIQISDIQKDLDKSKDELQKKQDRQNH 1957 Query: 754 DAKIQERDLYI--ENIESELSKYKSRICRLEESIAVMEDR-----RYSLE-RKADQLGSY 805 K ++R L +++ L + SRI L + + M+D R SL+ K + Sbjct: 1958 QVKPEKRLLSDGQQHLTESLREKCSRIKELLKRYSEMDDHYECLNRLSLDLEKEIEFQKE 2017 Query: 806 LQEKQKAYSEYTIQEDELVNRLAVL-----MDHDRVVEKQLLEIEHENKELQKKNQIL-- 858 L + KA + + + +L M+ R+++K + + K +++++ + Sbjct: 2018 LSMRVKANLSLPYLQTKHIEKLFTANQRCSMEFHRIMKKLKYVLSYVTKIKEEQHESINK 2077 Query: 859 --------LEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDL-ESNLKR 909 +E+ + L I + +QQ + + L ++ + L+D ES Sbjct: 2078 FEMDFIDEVEKQKELLIKIQHLQQDCDVPSRELRDLKLNQNMDLHIEEILKDFSESEFPS 2137 Query: 910 ITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKN 969 I E Q ++ +K+ + LE NT+ + EK + I+ Q+ + N Sbjct: 2138 IKTEFQQVLSNRKEMTQFLEEWLNTRFDI---------EKLKNGIQKENDRICQVNNFFN 2188 Query: 970 NIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALN 1029 N MN + I K ++ + E+ L L ++ Sbjct: 2189 NRIIAIMNESTEFEERSATISKEWEQDLKSLKEKNEKLFKNYQTLKTSLAS-GAQVNPTT 2247 Query: 1030 QKINNAQVSYMSM------VSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQI 1083 Q N V+ + + + E+ L + + E ++ ++ K+L + +LQ Sbjct: 2248 QDNKNPHVTSRATQLTTEKIRELENSLHEAKESAMHKESKIIKMQKELEVTNDIIAKLQA 2307 Query: 1084 LVREQDDQIKELKET 1098 V E + +++ KET Sbjct: 2308 KVHESNKCLEKTKET 2322 Score = 55.2 bits (127), Expect = 1e-05 Identities = 148/709 (20%), Positives = 296/709 (41%), Gaps = 71/709 (10%) Query: 320 NMTELTKKIELLEHLNCQIRQTNKELEN-KLATMGTESKAVSSPSKKGSPLISRKSGRNT 378 ++ E KK+ +E L QI+ + L ++ + K + + S + R + R Sbjct: 1818 DVNETQKKVSEMEQLKKQIKDQSLTLSKLEIENLNLAQKLHENLEEMKSVMKERDNLRRV 1877 Query: 379 ASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDK-EYVISEKDTXXXX 437 +K QL E+L + + + + K ++ +K+ VDK ISEK T Sbjct: 1878 EETLKLERDQLK-ESLQETKARDLEIQQELKTARMLSKEHKETVDKLREKISEK-TIQIS 1935 Query: 438 XXXXXXGKDTLIAQLQLEHQQHMEGPS--LIHVGTN--TEDVNE-IAKVQEQLKQ--ELN 490 K Q + + Q H P L+ G TE + E ++++E LK+ E++ Sbjct: 1936 DIQKDLDKSKDELQKKQDRQNHQVKPEKRLLSDGQQHLTESLREKCSRIKELLKRYSEMD 1995 Query: 491 DEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKV 550 D + +N L L EI+ + ++VK+N L Q + F+ Sbjct: 1996 DHYECLNRLSL------------DLEKEIEFQKELSMRVKANLSLPYLQTKHIEKLFTAN 2043 Query: 551 SDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAE 610 + E R+ ++L ++ V +++EE+ + ++ + D +E + +I++++L + Sbjct: 2044 QRCSMEFHRIMKKLKYVLSYVTKIKEEQ-HESINKFEMDFIDEVEKQ-KELLIKIQHLQQ 2101 Query: 611 TRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDA 670 L K + +LHI E+ L D S+ SE S+ E Q Sbjct: 2102 DCDVPSRELRDLKLNQNMDLHI--------EEILKDFSE-------SEFPSIKTEFQ--Q 2144 Query: 671 LSASKKELALVIE---NLKLDKEQLYGTIKDLENDKE-DIMNKLQNYIQENMDLTDKLEK 726 + +++KE+ +E N + D E+L I+ END+ + N N I M+ + + E+ Sbjct: 2145 VLSNRKEMTQFLEEWLNTRFDIEKLKNGIQK-ENDRICQVNNFFNNRIIAIMNESTEFEE 2203 Query: 727 MSA------EKISELLAKINHEEQSKIQT-QFGIDAKIQERDLYIENIESELSKYKSRIC 779 SA E+ + L + N + QT + + + Q +N ++ +++ Sbjct: 2204 RSATISKEWEQDLKSLKEKNEKLFKNYQTLKTSLASGAQVNPTTQDNKNPHVTSRATQL- 2262 Query: 780 RLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEK 839 E I +E+ + + A S + + QK E + D + A + + ++ +EK Sbjct: 2263 -TTEKIRELENSLHEAKESAMHKESKIIKMQK---ELEVTNDIIAKLQAKVHESNKCLEK 2318 Query: 840 QLLEIEHENKELQKKNQILLEENQNLQISL--SDMQQHYNALVEKANRTDLAESESTKYQ 897 I+ ++ + EE ++L++ L D+++ NA ++ + A + +YQ Sbjct: 2319 TKETIQVLQDKVALGAKPYKEEIEDLKMKLVKIDLEKMKNA--KEFEKEISATKATVEYQ 2376 Query: 898 TQ-LRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAI-RDKKVL-----NEKY 950 + +R L NL+R T ++ + + + S I ++ K L + + Sbjct: 2377 KEVIRLLRENLRRSQQAQDTSVISEHTDPQPSNKPLTCGGGSGIVQNTKALILKSEHIRL 2436 Query: 951 EKNIEYVTQLEAQLQEYKNNIENLNMNV-EELNKMNLELIDKHVQKQQT 998 EK I + Q QL + KN + + N ++ E+ + + KQ T Sbjct: 2437 EKEISKLKQQNEQLIKQKNELLSNNQHLSNEVKTWKERTLKREAHKQVT 2485 >UniRef50_Q231C5 Cluster: Putative uncharacterized protein; n=1; Tetrahymena thermophila SB210|Rep: Putative uncharacterized protein - Tetrahymena thermophila SB210 Length = 1759 Score = 162 bits (394), Expect = 6e-38 Identities = 274/1426 (19%), Positives = 604/1426 (42%), Gaps = 119/1426 (8%) Query: 212 EDTKQQMTKMQENFIAMEAEWKDEKQRLL--KDIESKDV-RISSLEEANKLLEAARFEIS 268 ++ KQ+ K ++ F+ ++ D +++L K+I K+V RI +LEE K + S Sbjct: 214 DEIKQKYLKYKQQFMEQRQQFTDLEKKLADEKEINVKNVSRIKTLEEQIKGQLLKLGQES 273 Query: 269 LEHSKLAQELEQXXXXXXXXXXXXXXL-AKQSIEPS--CEEKTEIEEKGSLEIANMTELT 325 E + EL+ L + Q E + + E++EK + ++ + ++ Sbjct: 274 KEKEEAKNELKNVLTKHQNLEQQILILQSNQQNEQTGLSNQLNELQEKYNQIVSYLIQIQ 333 Query: 326 --------KKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRN 377 K+++ ++ + +++ + + + + ++ +++ S++ + Sbjct: 334 QTLSCDQGKELDYIQQVMNSLQEQDDQQGQYIIKIQQQTSMINNLSQEKQTYLKENQQLK 393 Query: 378 TASKMKSPWSQLSSETLNQDTDKKINK-----NEIAKL----EMVIQSLNKDLVDKEYVI 428 + +Q NQ+ ++ N+I+++ E I L L KE + Sbjct: 394 LEIQKLEKQNQTIVLNFNQNESSYQSQIQELQNQISQIQNDAEKAITDLQSQLQSKEQEL 453 Query: 429 SEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQE 488 ++ + +I + + QQ + L+ ++ + K QEQ + Sbjct: 454 EQEKLSIVEFNEKEKELNLIINNYEAQLQQTQQEIQLLKDDLKNRELQQ--KNQEQSIIK 511 Query: 489 LNDEIKDVN--VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDN 546 DE K + + L + + S + N E++A + + + ++ Q+Q+ +D Sbjct: 512 FQDENKALQKQILSLNDVINSNQINQQHNNQELEAQKNQLAQQLEDRNQEISQLQQNLDL 571 Query: 547 FS-KVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIES-DVYKKMIE 604 + + S + E+ + L H Q+ +L+ E N Q + +D ++ + D+Y++ Sbjct: 572 LNQEKSQLSVELQEAKQILQHSKQEFEDLQTE-FNSQFNQYQFDIQQLKQQIDIYEQ--N 628 Query: 605 MENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHL 664 +NL E I L ++ L Q+ +QK+ + + +++ LQ D + E + +L Sbjct: 629 NKNLQE----QIKQLSNENDQLSQDFKNNEQKFIQSSKEFSEL-HLQFDTLQKE--NTNL 681 Query: 665 EEQIDALSASKKELALVIENLKLDKEQLYGTI----KDLENDKEDIMNKLQN----YIQE 716 + QI + K L+L E K Y + ++ D + + NK + + QE Sbjct: 682 KNQITQQAEQIKSLSLQGEEGIKQKSVEYAALLLKFNSIDKDHQSLQNKFSDSTNQFEQE 741 Query: 717 ----NMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDA-KI--QERDLYIENIES 769 N L DK E+ EK++++ + ++ I+ + +DA K+ Q I N Sbjct: 742 KKKLNQQLKDKQEQFD-EKVAKITSDLDQTRAEVIKVKQELDASKVANQSSQQIISNQTL 800 Query: 770 ELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAV 829 +++ S + L+ A + ++ S K L + L + E + ++ Sbjct: 801 QINSLTSTVEELKAGGASVSEQAQSYLTKIQTLEASLASQTLKLDEANSKNSAYEQQIQS 860 Query: 830 LMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLA 889 + +VV++Q+ ++E E LQ++ + L+E QN Q + +Q N ++ + L Sbjct: 861 QQNQIQVVQEQIKQLEQEKIVLQEQIESHLDEIQNHQEQMKQLQLENNNFEDQVKQLRLE 920 Query: 890 ESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEK 949 + QL +++L+ + + + K+++ L ++++QI+ + + L E+ Sbjct: 921 IVNQEENIKQLEFTKNSLEEQIQQLEQQLDNKEEQFNHLNEQYDSQIKGLQQQNEGLLEE 980 Query: 950 YEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYIN 1009 + + + + +++ IE + E++N N +LI K +K Q Q + EQ + Sbjct: 981 LKNKEQDLILCQNEIKNLNIQIEQEKESCEQINVQNEDLI-KQGEKHQEQISNLEEQ-LK 1038 Query: 1010 EINKLNALLKQKDEEIIALNQKINNAQVSYMSMVS---DYESKLAQFTT-KLENMEEEMQ 1065 + K NA +Q+ + A + + NN S ++ + D ++ AQ +++N +EE++ Sbjct: 1039 LLQKKNAQYQQQIQVFEASSNEENNELCSKLNQLQQNLDDVNEQAQLQQGQIQNAQEEIE 1098 Query: 1066 RVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDA 1125 ++Q+ ++ N ++I E + I L T T N K + +++ E + Sbjct: 1099 EKNQQIKQLEEFNSNMKIKHDEYEMTISSLNITIQTHLENQRKLDQLLLEKEKEIQTIQE 1158 Query: 1126 NNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTEL 1185 N+ + Q ++ ++E+ + Q++ KL +QE I +L++ N L Sbjct: 1159 ENISLTK----------EQQLIQQSLEEKLMAQKEQEKL--AIQEKQQTIDELQSENESL 1206 Query: 1186 TGHDVVN-QEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLA 1244 H + N +EQI + +EQ + + + + +++ + + Q G + + + Q L Sbjct: 1207 Q-HQLNNLEEQIRNNQQLIEQKDQQLYEVSQKLEQIQQE-QAQITQEGAKQNQEYDQKLQ 1264 Query: 1245 QREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEE 1304 EA Q+ E EL+ ++ + + + L ++ ++ K + + L+++LQ+ E Sbjct: 1265 NHEALAQQNE-ELQHEIEIKQDEIQSLQQKIKLLEDDQREK---HQDIEDLKHQLQEMSE 1320 Query: 1305 HLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQE 1364 + +++Y + + + L+ EI L + SY+Q + Sbjct: 1321 QNQGTEQRYTNQMEETLALQMEIRQ-----LHAQIQESHAENNNKDGLIAQLNSYEQDNQ 1375 Query: 1365 QSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYT 1424 + E+ +L K+ +N + ++ +LT QL +I Sbjct: 1376 CLEEKVQEQEVELNKAQ----QTISENQIEINKCKNQIADLTAQLVSLKEQI-------- 1423 Query: 1425 ITLTQRNDEFENVRQQLVEYEKRIEDLTYE-KESELAILRLKMHENANHYETMQ----KE 1479 Q N + + YE++ L E KE LA + +NA Y+ Q E Sbjct: 1424 ----QENSPSK------IGYEEKYHKLNKEYKEQILAFREQESEQNAKIYQMKQAIETNE 1473 Query: 1480 SEIERVKL-IEELNVKITE-SVSLNKQVAELNKALEEEVAKTNEMQTALENQEI-EIVTL 1536 I + + I +L KIT L Q E +A+ E NE + +L+NQE+ E +T Sbjct: 1474 ETISNLNIEISDLMYKITGLERELELQTNEF-EAIRAEKEYLNE-KLSLKNQELEESLTQ 1531 Query: 1537 NDEITNLQNMVRASSSKIQKHVSFASDTKQ--GRDEQLDNTMNKEL 1580 N + ++ + +++ K + +Q ++++L N +N+ L Sbjct: 1532 NQQNSHNNDNSHTDNTQSDKIYLYQEQIEQLTHKNQELQNRLNEIL 1577 Score = 161 bits (391), Expect = 1e-37 Identities = 234/1149 (20%), Positives = 491/1149 (42%), Gaps = 92/1149 (8%) Query: 447 TLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLK 506 TL Q+ L + ++ ++ ++ V +Q ++K + D I+ N + + Sbjct: 131 TLQIQINLNLIKEVDFTNMSQASNMSKAVAADMFIQNEVKAQ--DHIQQSNQTHAQQVQQ 188 Query: 507 SAEEQITQLNDEIDAANKNMIKVKSNHKLK---LKQMQKTIDNFSKVSDSNKEIVRLTEE 563 Q +++ N +SN ++K LK Q+ ++ + +D K++ E Sbjct: 189 QIHHQQNMQQNQM-MVQSNTASQESNDEIKQKYLKYKQQFMEQRQQFTDLEKKLADEKEI 247 Query: 564 LHHLSQKVAELEEE-KGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQ 622 ++ LEE+ KG L + ++++ + + +NL + L S +++ Sbjct: 248 NVKNVSRIKTLEEQIKGQLLKLGQESKEKEEAKNELKNVLTKHQNLEQQILILQSNQQNE 307 Query: 623 KFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSV-HLEEQIDALSASKKELALV 681 + L +L+ LQ+KY+++ L I Q S C + K + ++++ +++L + Sbjct: 308 QTGLSNQLNELQEKYNQIVSYLIQIQQTLS---CDQGKELDYIQQVMNSLQEQDDQQGQY 364 Query: 682 IENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINH 741 I +K+ +Q I +L +K Q Y++EN L +++K+ + ++ N Sbjct: 365 I--IKI--QQQTSMINNLSQEK-------QTYLKENQQLKLEIQKLEKQN-QTIVLNFNQ 412 Query: 742 EE---QSKIQTQFGIDAKIQ-ERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLER 797 E QS+IQ ++IQ + + I +++S+L + + + + SI ++ L Sbjct: 413 NESSYQSQIQELQNQISQIQNDAEKAITDLQSQLQSKEQELEQEKLSIVEFNEKEKELNL 472 Query: 798 KADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKK--- 854 + + LQ+ Q+ E + +D+L NR L ++ E+ +++ + ENK LQK+ Sbjct: 473 IINNYEAQLQQTQQ---EIQLLKDDLKNR--ELQQKNQ--EQSIIKFQDENKALQKQILS 525 Query: 855 -NQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHE 913 N ++ N Q + +++ N L ++ + S+ + L +S L E Sbjct: 526 LNDVINSNQINQQHNNQELEAQKNQLAQQLEDRNQEISQLQQNLDLLNQEKSQLSVELQE 585 Query: 914 HQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEK---YEKN----IEYVTQLEAQ--- 963 + ++ K+E EDL+ EFN+Q D + L ++ YE+N E + QL + Sbjct: 586 AKQILQHSKQEFEDLQTEFNSQFNQYQFDIQQLKQQIDIYEQNNKNLQEQIKQLSNENDQ 645 Query: 964 -LQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNAL----L 1018 Q++KNN + + +E ++++L+ +QK+ T + Q +I L+ + Sbjct: 646 LSQDFKNNEQKFIQSSKEFSELHLQF--DTLQKENTNLKNQITQQAEQIKSLSLQGEEGI 703 Query: 1019 KQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHN 1078 KQK E AL K N S+ D++S +F+ E+E +++++QL D ++ Sbjct: 704 KQKSVEYAALLLKFN-------SIDKDHQSLQNKFSDSTNQFEQEKKKLNQQLKDKQEQF 756 Query: 1079 EELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXX 1138 +E + DQ + + K+ E++ K I + N++ Sbjct: 757 DEKVAKITSDLDQTR-AEVIKVKQELDASKVANQSSQQIISNQTLQINSLTSTVEELKAG 815 Query: 1139 XXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQ 1198 + ++ + ++ + L+ A +L E +K E V QEQI Q Sbjct: 816 GASVS-EQAQSYLTKIQTLEASLASQTLKLDEANSKNSAYEQQIQSQQNQIQVVQEQIKQ 874 Query: 1199 LKSKLEQLNTENDNLLSTVAELRSSISS-AVDQRGFEIAELWKQHLAQREADFQKTEHEL 1257 L+ + L + ++ L + + + ++ FE + KQ L + ++ +L Sbjct: 875 LEQEKIVLQEQIESHLDEIQNHQEQMKQLQLENNNFE--DQVKQ-LRLEIVNQEENIKQL 931 Query: 1258 RVQLSAFESKYEQLLDSVQSSTQEETNKIVTM--EQVTSLQNKLQDKEEHLRNLQEKYAD 1315 ++ E + +QL + + +E+ N + Q+ LQ + + E L+N ++ Sbjct: 932 EFTKNSLEEQIQQLEQQLDNK-EEQFNHLNEQYDSQIKGLQQQNEGLLEELKNKEQDLIL 990 Query: 1316 VINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENA 1375 N+I+ L +IE EK DL + + + QEQ I N+ E+ Sbjct: 991 CQNEIKNLNIQIEQEK--------ESCEQINVQNEDLIKQGEKH---QEQ-ISNLEEQLK 1038 Query: 1376 QLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFE 1435 L+K + N+ ++ +QL+ ++ ++ + +E E Sbjct: 1039 LLQKKNAQYQQQIQVFEASSNEENNELCSKLNQLQQNLDDVNEQAQLQQGQIQNAQEEIE 1098 Query: 1436 NVRQQLVEYEK-----RIEDLTYEKESELAILRLKMH-ENANHYETMQKESEIERVKLIE 1489 QQ+ + E+ +I+ YE + ++ H EN + + E E E ++ I+ Sbjct: 1099 EKNQQIKQLEEFNSNMKIKHDEYEMTISSLNITIQTHLENQRKLDQLLLEKEKE-IQTIQ 1157 Query: 1490 ELNVKITESVSLNKQVAE--LNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMV 1547 E N+ +T+ L +Q E L E+E E Q ++ + E +L ++ NL+ + Sbjct: 1158 EENISLTKEQQLIQQSLEEKLMAQKEQEKLAIQEKQQTIDELQSENESLQHQLNNLEEQI 1217 Query: 1548 RASSSKIQK 1556 R + I++ Sbjct: 1218 RNNQQLIEQ 1226 Score = 153 bits (371), Expect = 4e-35 Identities = 266/1398 (19%), Positives = 596/1398 (42%), Gaps = 145/1398 (10%) Query: 216 QQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLA 275 Q + K+Q+ +M EKQ LK+ + + I LE+ N+ + + + Sbjct: 363 QYIIKIQQQ-TSMINNLSQEKQTYLKENQQLKLEIQKLEKQNQTIVLNFNQNESSYQSQI 421 Query: 276 QELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIEL-LEHL 334 QEL+ A ++ + K + E+ L I E K++ L + + Sbjct: 422 QELQNQISQIQNDAEK----AITDLQSQLQSKEQELEQEKLSIVEFNEKEKELNLIINNY 477 Query: 335 NCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETL 394 Q++QT +E++ L +++ + +++ S + + + ++ S ++S + Sbjct: 478 EAQLQQTQQEIQ--LLKDDLKNRELQQKNQEQSIIKFQDENKALQKQILSLNDVINSNQI 535 Query: 395 NQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQL 454 NQ + + +LE L + L D+ IS+ K L +LQ Sbjct: 536 NQQHNNQ-------ELEAQKNQLAQQLEDRNQEISQLQQNLDLLNQE---KSQLSVELQ- 584 Query: 455 EHQQHMEGPSLIHVGTNTEDVNEIAKVQ---EQLKQELNDEIKDVNVKDLIEKLKSAEEQ 511 E +Q ++ TE ++ + Q +QLKQ++ +I + N K+L E++K Q Sbjct: 585 EAKQILQHSKQEFEDLQTEFNSQFNQYQFDIQQLKQQI--DIYEQNNKNLQEQIK----Q 638 Query: 512 ITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNK-EIVRLTEELHHLSQK 570 ++ ND++ KN + + ++ D K + + K +I + E++ LS Sbjct: 639 LSNENDQLSQDFKNNEQKFIQSSKEFSELHLQFDTLQKENTNLKNQITQQAEQIKSLS-- 696 Query: 571 VAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQEL 630 L+ E+G ++ V+Y + + + + K + ++L + + E +K L Q+L Sbjct: 697 ---LQGEEG-IKQKSVEYAALLLKFNSIDK---DHQSLQNKFSDSTNQFEQEKKKLNQQL 749 Query: 631 HILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKE 690 Q+++DE K+A I+ DQ +E+ + +++++DA + + +I N L Sbjct: 750 KDKQEQFDE---KVAKITS-DLDQTRAEV--IKVKQELDASKVANQSSQQIISNQTLQIN 803 Query: 691 QLYGTIKDLENDKEDIMNKLQNYI-----------QENMDLTDKLEKMSA---------E 730 L T+++L+ + + Q+Y+ + + L + K SA Sbjct: 804 SLTSTVEELKAGGASVSEQAQSYLTKIQTLEASLASQTLKLDEANSKNSAYEQQIQSQQN 863 Query: 731 KISELLAKINHEEQSKIQTQFGIDAKIQE--------RDLYIE--NIESELSKYKSRICR 780 +I + +I EQ KI Q I++ + E + L +E N E ++ + + I Sbjct: 864 QIQVVQEQIKQLEQEKIVLQEQIESHLDEIQNHQEQMKQLQLENNNFEDQVKQLRLEIVN 923 Query: 781 LEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAV----LMDHDRV 836 EE+I +E + SLE + QL L K++ ++ Q D + L L++ + Sbjct: 924 QEENIKQLEFTKNSLEEQIQQLEQQLDNKEEQFNHLNEQYDSQIKGLQQQNEGLLEELKN 983 Query: 837 VEKQLLEIEHENKELQKKNQILLEENQNLQISLSDM----QQHYNALVEKANRTDLAESE 892 E+ L+ ++E K L + + E + + + D+ ++H + + L + + Sbjct: 984 KEQDLILCQNEIKNLNIQIEQEKESCEQINVQNEDLIKQGEKHQEQISNLEEQLKLLQKK 1043 Query: 893 STKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNT---QIESAIRDKKVLNEK 949 + +YQ Q++ E++ +E + + Q ++ ++D+ + QI++A + + N++ Sbjct: 1044 NAQYQQQIQVFEASSNEENNELCSKLNQLQQNLDDVNEQAQLQQGQIQNAQEEIEEKNQQ 1103 Query: 950 YEKNIEYVTQLEAQLQEYKNNIENLNMNV----EELNKMNLELIDKHVQKQQTQSPDYT- 1004 ++ E+ + ++ + EY+ I +LN+ + E K++ L++K + Q Q + + Sbjct: 1104 IKQLEEFNSNMKIKHDEYEMTISSLNITIQTHLENQRKLDQLLLEKEKEIQTIQEENISL 1163 Query: 1005 --EQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEE 1062 EQ + + + L+ QK++E +A+ +K + + +S+ +L N+EE Sbjct: 1164 TKEQQLIQQSLEEKLMAQKEQEKLAIQEK--------QQTIDELQSENESLQHQLNNLEE 1215 Query: 1063 EMQRVSKQLLDSKQH-----NEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISST 1117 ++ R ++QL++ K +++L+ + +EQ +E + ++ + E + Sbjct: 1216 QI-RNNQQLIEQKDQQLYEVSQKLEQIQQEQAQITQEGAKQNQEYDQKLQNHEAL----- 1269 Query: 1118 IEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQ 1177 + + + ++ +K+ E+++ +E+ + L +LQE + Sbjct: 1270 AQQNEELQHEIEIKQDEIQSLQQKIKLLEDDQ--REK---HQDIEDLKHQLQEMSEQNQG 1324 Query: 1178 LETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRS------SISSAVDQR 1231 E T + Q +I QL +++++ + EN+N +A+L S + V ++ Sbjct: 1325 TEQRYTNQMEETLALQMEIRQLHAQIQESHAENNNKDGLIAQLNSYEQDNQCLEEKVQEQ 1384 Query: 1232 GFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSST--QEETNKIVTM 1289 E+ + +Q +++ + + K ++++ + S EQ+ ++ S +E+ +K+ Sbjct: 1385 EVELNKA-QQTISENQIEINKCKNQIADLTAQLVSLKEQIQENSPSKIGYEEKYHKLNKE 1443 Query: 1290 EQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXX 1349 + L + Q+ E++ + Q K A N+ I IE + + Sbjct: 1444 YKEQILAFREQESEQNAKIYQMKQAIETNEETISNLNIEISDLMY-------KITGLERE 1496 Query: 1350 XDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQL 1409 +L+T N+ E+ LN E LK ND +H Sbjct: 1497 LELQT-NEFEAIRAEKEYLN---EKLSLKNQELEESLTQNQQNSHNNDN-------SHTD 1545 Query: 1410 ELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHEN 1469 + +IY E LT +N E +N +++ + ++E+ ++ L N Sbjct: 1546 NTQSDKIY-LYQEQIEQLTHKNQELQNRLNEILNQNIMNTPQSKDRENRNSVKSLSSPIN 1604 Query: 1470 ANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELN-KALEEEVAKTNEMQTALEN 1528 + Q + E+ +VK EL+ + V+ + + + K +++E+ K + +E Sbjct: 1605 NKTFANNQVDQELSQVKQDFELSKIELQKVTQERDMMKNEFKQMKQEIQKAKDSDKIIET 1664 Query: 1529 QEIEIVTLNDEITNLQNM 1546 ++V ++ ++ NM Sbjct: 1665 LTDQLVKSKQKLGDMYNM 1682 Score = 125 bits (302), Expect = 9e-27 Identities = 236/1253 (18%), Positives = 538/1253 (42%), Gaps = 100/1253 (7%) Query: 94 LANTLKQKEILMEKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKE 153 L T ++ ++L + +K + K +I++ L DV + SN I + Sbjct: 481 LQQTQQEIQLLKDDLKNRELQQKNQEQSIIKFQDENKALQKQILS--LNDVIN-SNQINQ 537 Query: 154 KDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXED 213 + N L+ + + + D ++I++ Q ++ N+ + + Sbjct: 538 QHNNQE-LEAQKNQLAQQLEDRNQEISQLQQNLDLLNQEKSQLSVELQEAKQIL----QH 592 Query: 214 TKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSK 273 +KQ+ +Q F + +++ + Q+L + I+ + +L+E K L ++S + Sbjct: 593 SKQEFEDLQTEFNSQFNQYQFDIQQLKQQIDIYEQNNKNLQEQIKQLSNENDQLSQDFKN 652 Query: 274 LAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEH 333 Q+ Q L K++ + + E+ SL + + +K Sbjct: 653 NEQKFIQSSKEFSELHLQFDTLQKENTNLKNQITQQAEQIKSLSLQGEEGIKQKSVEYAA 712 Query: 334 LNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGR--NTASKMKSPWSQLSS 391 L + +K+ ++ + KK + + K + +K+ S Q + Sbjct: 713 LLLKFNSIDKDHQSLQNKFSDSTNQFEQEKKKLNQQLKDKQEQFDEKVAKITSDLDQTRA 772 Query: 392 ETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQ 451 E + K+ K E+ ++ QS ++ ++ + + T + AQ Sbjct: 773 EVI------KV-KQELDASKVANQS-SQQIISNQTLQINSLTSTVEELKAGGASVSEQAQ 824 Query: 452 LQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQ 511 L Q +E SL ++ N EQ Q ++I+ V E++K E++ Sbjct: 825 SYLTKIQTLEA-SLASQTLKLDEANSKNSAYEQQIQSQQNQIQVVQ-----EQIKQLEQE 878 Query: 512 ITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKV 571 L ++I++ ++ +++ NH+ ++KQ+Q +NF ++ +L E+ + + + Sbjct: 879 KIVLQEQIES---HLDEIQ-NHQEQMKQLQLENNNF------EDQVKQLRLEIVNQEENI 928 Query: 572 AELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELH 631 +LE K +L+ + + +E + K + +L E I L+ Q L++EL Sbjct: 929 KQLEFTKNSLEEQI------QQLEQQLDNKEEQFNHLNEQYDSQIKGLQQQNEGLLEELK 982 Query: 632 ILQQKYDEVEDKLADIS-QLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKL--- 687 +Q ++++ +++ Q++ ++ E +V E+ I +++++ + E LKL Sbjct: 983 NKEQDLILCQNEIKNLNIQIEQEKESCEQINVQNEDLIKQGEKHQEQISNLEEQLKLLQK 1042 Query: 688 DKEQLYGTIKDLENDKEDIMNKL---QNYIQENMDLTDKLEKMSAEKISELLAKINHE-E 743 Q I+ E + N+L N +Q+N+D ++ ++ +I +I + + Sbjct: 1043 KNAQYQQQIQVFEASSNEENNELCSKLNQLQQNLDDVNEQAQLQQGQIQNAQEEIEEKNQ 1102 Query: 744 QSKIQTQFGIDAKIQ--ERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQ 801 Q K +F + KI+ E ++ I ++ + + +L++ + E +++ + Sbjct: 1103 QIKQLEEFNSNMKIKHDEYEMTISSLNITIQTHLENQRKLDQLLLEKEKEIQTIQEENIS 1162 Query: 802 LGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEE 861 L Q Q++ E + + E +LA+ + + ++ E++ EN+ LQ + L E+ Sbjct: 1163 LTKEQQLIQQSLEEKLMAQKE-QEKLAI-QEKQQTID----ELQSENESLQHQLNNLEEQ 1216 Query: 862 NQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQK 921 +N Q + Q + +K + +++ T+ + ++ E + K HE + Q+ Sbjct: 1217 IRNNQQLIEQKDQQLYEVSQKLEQIQQEQAQITQ-EGAKQNQEYDQKLQNHE---ALAQQ 1272 Query: 922 KKEIE-DLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNM---- 976 +E++ ++EI+ +I+S + K+L + + + + L+ QLQE + Sbjct: 1273 NEELQHEIEIK-QDEIQSLQQKIKLLEDDQREKHQDIEDLKHQLQEMSEQNQGTEQRYTN 1331 Query: 977 NVEELNKMNLELIDKHVQKQQTQSPDYTEQ----YINEINKLNALLKQK-DEEIIALNQK 1031 +EE + +E+ H Q Q++ + + + +N + N L++K E+ + LN+ Sbjct: 1332 QMEETLALQMEIRQLHAQIQESHAENNNKDGLIAQLNSYEQDNQCLEEKVQEQEVELNKA 1391 Query: 1032 INNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQ 1091 + + ++ ++++A T +L +++E++Q S + + E+ L +E +Q Sbjct: 1392 QQTISENQIE-INKCKNQIADLTAQLVSLKEQIQENSPSKIG---YEEKYHKLNKEYKEQ 1447 Query: 1092 IKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEE-EF 1150 I +E + I + + I + E +S+ + L++Q E E Sbjct: 1448 ILAFREQESEQNAKIYQMK-QAIETNEETISNLNIEISDLMYKITGLERELELQTNEFEA 1506 Query: 1151 IQ-ERSVLQEQSAKLNTELQECYTKIIQ----LETLNTELTGHDVV--NQEQINQLKSKL 1203 I+ E+ L E+ + N EL+E T+ Q + +T+ T D + QEQI QL K Sbjct: 1507 IRAEKEYLNEKLSLKNQELEESLTQNQQNSHNNDNSHTDNTQSDKIYLYQEQIEQLTHKN 1566 Query: 1204 EQLNTE-----NDNLLSTV----AELRSSI---SSAVDQRGFEIAELWKQHLAQREADFQ 1251 ++L N N+++T E R+S+ SS ++ + F ++ Q L+Q + DF+ Sbjct: 1567 QELQNRLNEILNQNIMNTPQSKDRENRNSVKSLSSPINNKTFANNQV-DQELSQVKQDFE 1625 Query: 1252 KTEHELR---VQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQD 1301 ++ EL+ + +++++Q+ +Q + + +Q+ + KL D Sbjct: 1626 LSKIELQKVTQERDMMKNEFKQMKQEIQKAKDSDKIIETLTDQLVKSKQKLGD 1678 >UniRef50_Q6FWE0 Cluster: Candida glabrata strain CBS138 chromosome D complete sequence; n=1; Candida glabrata|Rep: Candida glabrata strain CBS138 chromosome D complete sequence - Candida glabrata (Yeast) (Torulopsis glabrata) Length = 1980 Score = 162 bits (394), Expect = 6e-38 Identities = 266/1241 (21%), Positives = 539/1241 (43%), Gaps = 112/1241 (9%) Query: 376 RNTASKMKSPWSQL---SSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKD 432 +N + +KS S+L SSE +Q +K+I K+ + E + L K+L DK ISEK Sbjct: 703 QNQCTSLKSHLSELEIQSSEKRSQ-LEKQI-KSLTSNFE-ASEQLKKELEDKLSTISEKQ 759 Query: 433 TXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQ-EQLKQELND 491 K +A++ + SL + T E + E K Q K++L Sbjct: 760 QTLESEYEE---KKKELAEITANNT------SLEQLNTQKEKLTEELKKQLADTKEKLTQ 810 Query: 492 EIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVS 551 K V K+L E + E+ I ++N ++ + + K++ ++K K ++KT ++F+K Sbjct: 811 MEKQV--KELSEHKEKNEQGINKMNRDLFSLQREKQKLEEDNKQSKKDLEKTKNDFTKQE 868 Query: 552 DSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAET 611 K+ ++ E L + E E+ +Y I+ ++ +M E + ++ Sbjct: 869 TKLKDQIKAKEIL------IKETTEKLNEATTQSKEYHD--KIQ-NITSEMNEWQAKYKS 919 Query: 612 RLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVC---SEIKSVHLEEQI 668 ++ L + L LQ + D ++ +L I+Q + + SE KS LEE Sbjct: 920 HDTFVAKLTEKLKALATSFKELQAERDTIKSELEKITQERDTNIAAITSEKKS--LEELY 977 Query: 669 DALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMS 728 + + K L I L+ E K E++K + ++ + E + EK+ Sbjct: 978 KNMESEKDGLLKKITELETGIE---SDNKKFEDEKSALESETKRLTLEIAEFKSNAEKLD 1034 Query: 729 AEKISELLAKINHEEQSKI-QTQFGIDAK---IQERDLYIENIESELSKYKSRICRLEES 784 E+ E L + + K+ + ID K + IE +SE+S K+ I +L+ S Sbjct: 1035 TER--ERLQTLTESYKEKLNEANSSIDEKNKDLNNIQQQIEGSQSEISTLKAEITQLKTS 1092 Query: 785 IAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEI 844 + + R +LE+ ++ +Y+Q Q + + D L + +D++ ++++ E+ Sbjct: 1093 LNEEKSTRKALEKLKEENETYIQSAQDELLQLQKEVDLLKSENKDALDNNSSLKQKYDEL 1152 Query: 845 EHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLE 904 KEL+ KN LE Q LSD + N+ +E+ L +KY T +++LE Sbjct: 1153 V---KELELKN---LESKQ-----LSDNSLNLNSKIEQ-----LEGDIKSKYNT-IKELE 1195 Query: 905 SNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNE---KYEKNIEYVTQLE 961 L E + I I D+E++ N++ E L E +EK +LE Sbjct: 1196 EKLSTSLQEREENIA----NIADIELKLNSKEEQYTEQTNKLEELRISFEKKQSECKELE 1251 Query: 962 AQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQ- 1020 ++L+ ++++ N +EL K NL+ + K +K + E E K + Q Sbjct: 1252 SKLKSSNDDLQEKNRLTKELQK-NLDSLMKDKEKTEGSLQSLLEDKKQEEKKYKEEIDQL 1310 Query: 1021 --KDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHN 1078 ++E+I N+++N Y + + + +L + + +++M ++ +++ D Sbjct: 1311 GKENEDITKQNKELNLRLEDYSAKIDAKDEELKLANDAVASTKKKMLKLEEKIKDL---- 1366 Query: 1079 EELQILVREQDDQIK-ELKETKLTFEM------NIPKTEGMIISSTIEPMSDDANNVDXX 1131 E+ Q + ++ ++ +K EL++T L NI K + + + + + ++ + Sbjct: 1367 EDTQHIFKDSENSLKSELEKTALEMNELRSDNDNIIKLKNELQRTNDKLIEENKRTEEKL 1426 Query: 1132 XXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQ-LETLNTELTGHDV 1190 LK + + F +ER ++ E S+ + E E + + + +ET+ +E Sbjct: 1427 RSEVAKLKDELKT-KSDTFEKERKLMNEDSSTIIKEYSEKISSLEEKVETIKSEY----- 1480 Query: 1191 VNQEQINQLKSKLEQLNTENDNLLSTVAELRSSI---SSAVDQRGFEIAELWKQHLAQRE 1247 ++IN L+ K E L +E + + + I + ++ EI ++ K L E Sbjct: 1481 --DKEINILEDKKEVLESELSDKKQEIIDYNQKIKEQETKATEKEKEI-QVAKNALKNAE 1537 Query: 1248 ADFQKTEHELRVQLSAFESKYEQLLDSVQ---SSTQEETNKIVTMEQVTSLQNKLQDKE- 1303 + E++LR ++ E + L Q S + N I +++ S Q +L DK+ Sbjct: 1538 KKKKDIENDLRTTIATVEKENTTLKRENQLKSESIDKHQNNIHLLQEELSKQKELADKKH 1597 Query: 1304 EHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQ 1363 + +R L+++ + +I++I+ ++E +K + +T + + Q Sbjct: 1598 DEIRKLEKENSKMIDRID----KLEKQKADTNEKIANIEKENSSLISERKTLVEKVENFQ 1653 Query: 1364 EQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEY 1423 ++ I N+ + S + + + EL ++LE ++ ++ K E+ Sbjct: 1654 DE-ITNLKSSLEKNDSLSSSHDELKDKFNELETELKRNLTEL-NKLESENKQLSDKVIEH 1711 Query: 1424 TITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYE--TMQKESE 1481 ++ E ++ L E E I L + +EL K HYE +K+S+ Sbjct: 1712 EEKVSMVEKELSTAQKTLKEREDVINKLK-DSNNELNKTIDKHGATEKHYEESITKKDSD 1770 Query: 1482 IERV-KLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEI 1540 I ++ K I+++ K++ + + A L LE++ ++ L+ QE+E + Sbjct: 1771 IAQLKKKIKDIEDKLSNILEEKAKAAMLMTQLEKDKTDLKNSESELK-QELE--HYRSKY 1827 Query: 1541 TNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELL 1581 ++L++ ++ S+ + +KHV S +Q + LD K+ L Sbjct: 1828 SSLESKLK-STEEAKKHVEEES-REQHQSMSLDLKATKDKL 1866 Score = 153 bits (370), Expect = 5e-35 Identities = 270/1348 (20%), Positives = 584/1348 (43%), Gaps = 142/1348 (10%) Query: 296 AKQSIEPSCEE-KTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGT 354 A + ++ C K+ + E ++L K+I+ L Q KELE+KL+T+ Sbjct: 698 AFEEVQNQCTSLKSHLSELEIQSSEKRSQLEKQIKSLTSNFEASEQLKKELEDKLSTISE 757 Query: 355 ESKAVSSPSKKGSPLISRKSGRNTA-SKMKSPWSQLSSETLNQ--DTDKKINKNE----- 406 + + + S ++ ++ + NT+ ++ + +L+ E Q DT +K+ + E Sbjct: 758 KQQTLESEYEEKKKELAEITANNTSLEQLNTQKEKLTEELKKQLADTKEKLTQMEKQVKE 817 Query: 407 ----IAKLEMVIQSLNKDL--VDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHM 460 K E I +N+DL + +E E+D D + +L+ Q + Sbjct: 818 LSEHKEKNEQGINKMNRDLFSLQREKQKLEEDNKQSKKDLEKTKNDFTKQETKLKDQ--I 875 Query: 461 EGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEID 520 + ++ + TE +NE ++ ++ + ++N + K KS + + +L +++ Sbjct: 876 KAKEIL-IKETTEKLNEATTQSKEYHDKIQNITSEMN--EWQAKYKSHDTFVAKLTEKLK 932 Query: 521 AANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGN 580 A + ++++ +++K ++ D+N I +T E L + +E EK Sbjct: 933 ALATSFKELQAERDTIKSELEK----ITQERDTN--IAAITSEKKSLEELYKNMESEKDG 986 Query: 581 LQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISL------LESQKFDLVQE-LHIL 633 L + + ++G IESD KK + ++ E+ K ++L ++K D +E L L Sbjct: 987 LLKKITELETG--IESD-NKKFEDEKSALESETKRLTLEIAEFKSNAEKLDTERERLQTL 1043 Query: 634 QQKYDE--------VEDKLADISQLQSDQVCSEIKSVHLEEQIDALSAS---KKELALVI 682 + Y E +++K D++ +Q S+ + L+ +I L S +K + Sbjct: 1044 TESYKEKLNEANSSIDEKNKDLNNIQQQIEGSQSEISTLKAEITQLKTSLNEEKSTRKAL 1103 Query: 683 ENLKLDKEQLYGTIKD--LENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKIN 740 E LK + E + +D L+ KE + K +N ++ +D L++ E + EL K N Sbjct: 1104 EKLKEENETYIQSAQDELLQLQKEVDLLKSEN--KDALDNNSSLKQKYDELVKELELK-N 1160 Query: 741 HEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAV-MEDRRYSLERKA 799 E + +++K IE +E ++ + I LEE ++ +++R ++ A Sbjct: 1161 LESKQLSDNSLNLNSK-------IEQLEGDIKSKYNTIKELEEKLSTSLQEREENIANIA 1213 Query: 800 DQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILL 859 D + L K++ Y+E T + +EL R++ E + +++ N +LQ+KN++ Sbjct: 1214 D-IELKLNSKEEQYTEQTNKLEEL--RISFEKKQSECKELE-SKLKSSNDDLQEKNRLTK 1269 Query: 860 EENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIV 919 E +NL + D ++ +L + + + E KY+ ++ L + IT +++ L + Sbjct: 1270 ELQKNLDSLMKDKEKTEGSL---QSLLEDKKQEEKKYKEEIDQLGKENEDITKQNKELNL 1326 Query: 920 Q-----KKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQL-EAQLQEYKNNIEN 973 + K + +D E++ ++ + K + E+ K++E + + K+ +E Sbjct: 1327 RLEDYSAKIDAKDEELKLANDAVASTKKKMLKLEEKIKDLEDTQHIFKDSENSLKSELEK 1386 Query: 974 LNMNVEELNKMNLELIDKHVQKQQT-----QSPDYTEQYI-NEINKLNALLKQKDEEIIA 1027 + + EL N +I + Q+T + TE+ + +E+ KL LK K + Sbjct: 1387 TALEMNELRSDNDNIIKLKNELQRTNDKLIEENKRTEEKLRSEVAKLKDELKTK-SDTFE 1445 Query: 1028 LNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRV------SKQLLDSKQHNEEL 1081 +K+ N S +++ +Y K++ K+E ++ E + K++L+S+ +++ Sbjct: 1446 KERKLMNEDSS--TIIKEYSEKISSLEEKVETIKSEYDKEINILEDKKEVLESELSDKKQ 1503 Query: 1082 QILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXX 1141 +I+ Q + +E K T+ E+ + K + + + D N++ Sbjct: 1504 EIIDYNQKIKEQETKATEKEKEIQVAKN---ALKNAEKKKKDIENDLRTTIATVEKENTT 1560 Query: 1142 LKVQEE--EEFIQERS----VLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQ 1195 LK + + E I + +LQE+ +K + + +I +LE N+++ ++Q Sbjct: 1561 LKRENQLKSESIDKHQNNIHLLQEELSKQKELADKKHDEIRKLEKENSKMIDRIDKLEKQ 1620 Query: 1196 INQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEH 1255 K+ + EN +L+S R ++ V+ EI L K L + ++ + Sbjct: 1621 KADTNEKIANIEKENSSLISE----RKTLVEKVENFQDEITNL-KSSLEKNDS-LSSSHD 1674 Query: 1256 ELRVQLSAFESKYEQ---LLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEK 1312 EL+ + + E++ ++ L+ ++S ++ ++K++ E+ S+ K + + L+E+ Sbjct: 1675 ELKDKFNELETELKRNLTELNKLESENKQLSDKVIEHEEKVSMVEK--ELSTAQKTLKER 1732 Query: 1313 YADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINE 1372 DVIN+++ +E+ D ++ + ++ E+SI + Sbjct: 1733 -EDVINKLKDSNNELN-------------------KTID---KHGATEKHYEESITKKDS 1769 Query: 1373 ENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRND 1432 + AQLKK + + +AK L QLE +++ E L Sbjct: 1770 DIAQLKKK----IKDIEDKLSNILEEKAKAAMLMTQLEKDKTDLKNSESELKQELEHYRS 1825 Query: 1433 EFENVRQQL---VEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEI--ERVKL 1487 ++ ++ +L E +K +E+ + E+ +++ + E E + ++V+L Sbjct: 1826 KYSSLESKLKSTEEAKKHVEEESREQHQSMSLDLKATKDKLKSAEISISEMDAIKKQVEL 1885 Query: 1488 IEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMV 1547 + + NV + + A+L L +E+ K NE N E+ L +T L Sbjct: 1886 LTKENVDLKSKSNKADNSAKLKSEL-DELKKENEKLQLKVNDRSELDDLMLLVTELDEKN 1944 Query: 1548 RASSSKIQK-HVSFASDTKQGRDEQLDN 1574 K+ + V +SD + D+ D+ Sbjct: 1945 SKYREKLSELGVELSSDEEDDDDDDDDD 1972 Score = 126 bits (305), Expect = 4e-27 Identities = 209/1135 (18%), Positives = 479/1135 (42%), Gaps = 82/1135 (7%) Query: 99 KQKEILMEKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNAL 158 KQ+ L ++IK KE+ + +T + ++ K D + Sbjct: 866 KQETKLKDQIKA-KEILIKETTEKLNEATTQSKEYHDKIQNITSEMNEWQAKYKSHDTFV 924 Query: 159 SVLQVKMKIMETTILDLQEKIN----EKDQIIEAKNK---ATTXXXXXXXXXXXXXXXXX 211 + L K+K + T+ +LQ + + E ++I + ++ A T Sbjct: 925 AKLTEKLKALATSFKELQAERDTIKSELEKITQERDTNIAAITSEKKSLEELYKNMESEK 984 Query: 212 EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271 + +++T+++ + +++DEK L + + + I+ + + L+ R + Sbjct: 985 DGLLKKITELETGIESDNKKFEDEKSALESETKRLTLEIAEFKSNAEKLDTERERLQTLT 1044 Query: 272 SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEE----KTEIEE-KGSLEIANMTELTK 326 ++L + + +Q IE S E K EI + K SL T K Sbjct: 1045 ESYKEKLNEANSSIDEKNKDLNNI-QQQIEGSQSEISTLKAEITQLKTSLNEEKSTR--K 1101 Query: 327 KIELLEHLNCQIRQTNKE----LENKLATMGTESKAV----SSPSKKGSPLISRKSGRNT 378 +E L+ N Q+ ++ L+ ++ + +E+K SS +K L+ +N Sbjct: 1102 ALEKLKEENETYIQSAQDELLQLQKEVDLLKSENKDALDNNSSLKQKYDELVKELELKNL 1161 Query: 379 ASKMKSPWS-QLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXX 437 SK S S L+S+ + D K N I +LE + + ++ + I++ + Sbjct: 1162 ESKQLSDNSLNLNSKIEQLEGDIKSKYNTIKELEEKLSTSLQEREENIANIADIELKLNS 1221 Query: 438 XXXXXXGKDTLIAQLQLEHQQHMEGPSLIH--VGTNTEDVNEIAKVQEQLKQELNDEIKD 495 + + +L++ ++ + + ++ +D+ E ++ ++L++ L+ +KD Sbjct: 1222 KEEQYTEQTNKLEELRISFEKKQSECKELESKLKSSNDDLQEKNRLTKELQKNLDSLMKD 1281 Query: 496 V-----NVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTID-NFSK 549 +++ L+E K E++ + D++ N+++ K L+L+ ID + Sbjct: 1282 KEKTEGSLQSLLEDKKQEEKKYKEEIDQLGKENEDITKQNKELNLRLEDYSAKIDAKDEE 1341 Query: 550 VSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLA 609 + +N + +++ L +K+ +LE+ + H+ DS ++S++ K +EM L Sbjct: 1342 LKLANDAVASTKKKMLKLEEKIKDLEDTQ-----HIFK-DSENSLKSELEKTALEMNELR 1395 Query: 610 ETRLKAISL---LESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEE 666 I L L+ L++E ++K KL D + +SD E K ++ E+ Sbjct: 1396 SDNDNIIKLKNELQRTNDKLIEENKRTEEKLRSEVAKLKDELKTKSDTFEKERKLMN-ED 1454 Query: 667 QIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKL-- 724 + ++++ + E ++ K + I LE+ KE + ++L + QE +D K+ Sbjct: 1455 SSTIIKEYSEKISSLEEKVETIKSEYDKEINILEDKKEVLESELSDKKQEIIDYNQKIKE 1514 Query: 725 -EKMSAEKISEL-LAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLE 782 E + EK E+ +AK + K + D + I +E E + K Sbjct: 1515 QETKATEKEKEIQVAKNALKNAEKKKKDIENDLRTT-----IATVEKENTTLKRENQLKS 1569 Query: 783 ESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLL 842 ESI ++ + L+ + + +K + + ++++R+ L +++ Sbjct: 1570 ESIDKHQNNIHLLQEELSKQKELADKKHDEIRKLEKENSKMIDRIDKLEKQKADTNEKIA 1629 Query: 843 EIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRD 902 IE EN L + + L+E+ +N Q +++++ ++ D + + + +T+L+ Sbjct: 1630 NIEKENSSLISERKTLVEKVENFQDEITNLKSSLEKNDSLSSSHDELKDKFNELETELKR 1689 Query: 903 LESNLKRITHEHQTL---IVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQ 959 + L ++ E++ L +++ ++++ +E E +T ++ + V+N+ + N E Sbjct: 1690 NLTELNKLESENKQLSDKVIEHEEKVSMVEKELSTAQKTLKEREDVINKLKDSNNELNKT 1749 Query: 960 LE---AQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNA 1016 ++ A + Y+ +I + ++ +L K ++ DK + E K Sbjct: 1750 IDKHGATEKHYEESITKKDSDIAQLKKKIKDIEDK------------LSNILEEKAKAAM 1797 Query: 1017 LLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQ 1076 L+ Q +++ + N++ + Y SK + +KL++ EE + V + +S++ Sbjct: 1798 LMTQLEKD----KTDLKNSESELKQELEHYRSKYSSLESKLKSTEEAKKHVEE---ESRE 1850 Query: 1077 HNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXX 1136 ++ + + ++ D++K E ++ EM+ K + +++ + +N D Sbjct: 1851 QHQSMSLDLKATKDKLKS-AEISIS-EMDAIKKQVELLTKENVDLKSKSNKADNSAKLKS 1908 Query: 1137 XXXXXLKVQEEEEF-IQERSVLQEQSAKLNTELQECYTKIIQ-LETLNTELTGHD 1189 K E+ + + +RS L + L TEL E +K + L L EL+ + Sbjct: 1909 ELDELKKENEKLQLKVNDRSELDDLML-LVTELDEKNSKYREKLSELGVELSSDE 1962 Score = 118 bits (283), Expect = 2e-24 Identities = 168/844 (19%), Positives = 358/844 (42%), Gaps = 62/844 (7%) Query: 765 ENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELV 824 E ++++ + KS + LE + ++R LE++ L S + ++ E + + Sbjct: 700 EEVQNQCTSLKSHLSELEIQSS---EKRSQLEKQIKSLTSNFEASEQLKKELEDKLSTIS 756 Query: 825 NRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKAN 884 + L +K+L EI N L++ N + + L+ L+D ++ + ++ Sbjct: 757 EKQQTLESEYEEKKKELAEITANNTSLEQLNTQKEKLTEELKKQLADTKEKLTQMEKQVK 816 Query: 885 RTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFN--TQIESAIRD 942 +L+E + K + + + +L + E Q L K+ +DLE N T+ E+ ++D Sbjct: 817 --ELSEHKE-KNEQGINKMNRDLFSLQREKQKLEEDNKQSKKDLEKTKNDFTKQETKLKD 873 Query: 943 K-KVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELN---KMNLELIDKHVQKQQT 998 + K ++ E + + Q +EY + I+N+ + E K + + K +K + Sbjct: 874 QIKAKEILIKETTEKLNEATTQSKEYHDKIQNITSEMNEWQAKYKSHDTFVAKLTEKLKA 933 Query: 999 QSPDYTEQYINE---INKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTT 1055 + + E ++L + +++D I A+ + + + Y +M S+ + L + T Sbjct: 934 LATSFKELQAERDTIKSELEKITQERDTNIAAITSEKKSLEELYKNMESEKDGLLKKITE 993 Query: 1056 KLENMEEEMQRV--SKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMI 1113 +E + ++ K L+S+ L+I + + + + + +L K + Sbjct: 994 LETGIESDNKKFEDEKSALESETKRLTLEIAEFKSNAEKLDTERERLQTLTESYKEKLNE 1053 Query: 1114 ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYT 1173 +S+I+ + D NN+ Q+ E E S L+ + +L T L E + Sbjct: 1054 ANSSIDEKNKDLNNIQ---------------QQIEGSQSEISTLKAEITQLKTSLNEEKS 1098 Query: 1174 KIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGF 1233 LE L E + Q+++ QL+ +++ L +EN + L + L+ V + Sbjct: 1099 TRKALEKLKEENETYIQSAQDELLQLQKEVDLLKSENKDALDNNSSLKQKYDELVKE--L 1156 Query: 1234 EIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVT 1293 E+ L + L+ + +L + + + ++L + + +S QE I + + Sbjct: 1157 ELKNLESKQLSDNSLNLNSKIEQLEGDIKSKYNTIKELEEKLSTSLQEREENIANIADIE 1216 Query: 1294 SLQNKLQD-------KEEHLRNLQEKYADVINQIEI-LRSEIEDEKVAFXXXXXXXXXXX 1345 N ++ K E LR EK ++E L+S +D + Sbjct: 1217 LKLNSKEEQYTEQTNKLEELRISFEKKQSECKELESKLKSSNDDLQEKNRLTKELQKNLD 1276 Query: 1346 XXXXXDLRTEN--QSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVL 1403 +TE QS + ++Q EE QL K + R+ D AK+ Sbjct: 1277 SLMKDKEKTEGSLQSLLEDKKQEEKKYKEEIDQLGKENEDITKQNKELNLRLEDYSAKID 1336 Query: 1404 ELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILR 1463 +L+L + + T + + L ++ + E+ + + E + +SEL Sbjct: 1337 AKDEELKLANDAV-ASTKKKMLKLEEKIKDLEDTQHIFKDSENSL-------KSELEKTA 1388 Query: 1464 LKMHE-NANHYETMQKESEIERV--KLIEELNVKITESVSLNKQVAELNKALEEEVAKTN 1520 L+M+E +++ ++ ++E++R KLIEE N + E L +VA+L L+ + + T Sbjct: 1389 LEMNELRSDNDNIIKLKNELQRTNDKLIEE-NKRTEE--KLRSEVAKLKDELKTK-SDTF 1444 Query: 1521 EMQTALENQEIE--IVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNK 1578 E + L N++ I +++I++L+ V S+ K ++ D K+ + +L + + Sbjct: 1445 EKERKLMNEDSSTIIKEYSEKISSLEEKVETIKSEYDKEINILEDKKEVLESELSD-KKQ 1503 Query: 1579 ELLD 1582 E++D Sbjct: 1504 EIID 1507 Score = 106 bits (255), Expect = 4e-21 Identities = 173/824 (20%), Positives = 353/824 (42%), Gaps = 87/824 (10%) Query: 813 YSEY-TIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSD 871 ++EY TI E R+ HD E + +E+Q + L L+I S+ Sbjct: 663 FNEYFTILFKENFYRILRCFYHDPTDEPIAIVSFEAFEEVQNQCTSLKSHLSELEIQSSE 722 Query: 872 MQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTL---IVQKKKEIEDL 928 + + K+ ++ SE K ++LE L I+ + QTL +KKKE+ ++ Sbjct: 723 KRSQLEKQI-KSLTSNFEASEQLK-----KELEDKLSTISEKQQTLESEYEEKKKELAEI 776 Query: 929 EIEFNTQIESAIRDKKVLNEKYEKNI----EYVTQLEAQLQEYKNNIENLNMNVEELNKM 984 NT +E K+ L E+ +K + E +TQ+E Q++E + E N + +NKM Sbjct: 777 TAN-NTSLEQLNTQKEKLTEELKKQLADTKEKLTQMEKQVKELSEHKEK---NEQGINKM 832 Query: 985 NLELIDKHVQKQQT-----QSPDYTEQYINEINKLNALLKQ--KDEEIIA--LNQKINNA 1035 N +L +KQ+ QS E+ N+ K LK K +EI+ +K+N A Sbjct: 833 NRDLFSLQREKQKLEEDNKQSKKDLEKTKNDFTKQETKLKDQIKAKEILIKETTEKLNEA 892 Query: 1036 QVS---YMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQI 1092 Y + + S++ ++ K ++ + + +++++L +ELQ E+D Sbjct: 893 TTQSKEYHDKIQNITSEMNEWQAKYKSHDTFVAKLTEKLKALATSFKELQA---ERDTIK 949 Query: 1093 KELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKV---QEEEE 1149 EL+ K+T E + T I+S + + + N++ L+ + ++ Sbjct: 950 SELE--KITQERD---TNIAAITSEKKSLEELYKNMESEKDGLLKKITELETGIESDNKK 1004 Query: 1150 FIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTE 1209 F E+S L+ ++ +L E+ E + +L+T L +E++N+ S +++ N + Sbjct: 1005 FEDEKSALESETKRLTLEIAEFKSNAEKLDTERERLQTLTESYKEKLNEANSSIDEKNKD 1064 Query: 1210 NDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYE 1269 +N+ + +S IS+ K + Q + + E R L + + E Sbjct: 1065 LNNIQQQIEGSQSEISTL------------KAEITQLKTSLNE-EKSTRKALEKLKEENE 1111 Query: 1270 QLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIED 1329 + S Q + ++V L+++ +D ++ +L++KY +++ ++E+ +E Sbjct: 1112 TYIQSAQDEL------LQLQKEVDLLKSENKDALDNNSSLKQKYDELVKELEL--KNLES 1163 Query: 1330 EKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXX 1389 ++++ D++++ + K+++E+ ++ E + + Sbjct: 1164 KQLS--DNSLNLNSKIEQLEGDIKSKYNTIKELEEKLSTSLQEREENI-ANIADIELKLN 1220 Query: 1390 XXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIE 1449 + + K+ EL E K SE E L ND+ + + E +K ++ Sbjct: 1221 SKEEQYTEQTNKLEELRISFEKKQSE----CKELESKLKSSNDDLQEKNRLTKELQKNLD 1276 Query: 1450 DLTYEKE----SELAILRLKMHENANHYETMQ---KESEIERVKLIEELNVKITE-SVSL 1501 L +KE S ++L K E + E + KE+E + K +ELN+++ + S + Sbjct: 1277 SLMKDKEKTEGSLQSLLEDKKQEEKKYKEEIDQLGKENE-DITKQNKELNLRLEDYSAKI 1335 Query: 1502 NKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFA 1561 + + EL K + VA T + LE +I L D ++ + S+++K Sbjct: 1336 DAKDEEL-KLANDAVASTKKKMLKLEE---KIKDLEDTQHIFKDSENSLKSELEKTALEM 1391 Query: 1562 SDTKQGRDE--QLDNTM---NKELLDAVPRAELDLAMYMLHQRD 1600 ++ + D +L N + N +L++ R E L + +D Sbjct: 1392 NELRSDNDNIIKLKNELQRTNDKLIEENKRTEEKLRSEVAKLKD 1435 >UniRef50_A0CWT0 Cluster: Chromosome undetermined scaffold_3, whole genome shotgun sequence; n=1; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_3, whole genome shotgun sequence - Paramecium tetraurelia Length = 2043 Score = 161 bits (391), Expect = 1e-37 Identities = 257/1256 (20%), Positives = 575/1256 (45%), Gaps = 166/1256 (13%) Query: 396 QDTDKKINKNEIAKL-EMVIQSLNKDLVDK-EYVISEKDTXXXXXXXXXXGKDTLIAQLQ 453 Q + KI+ E+ KL E +IQ +++D +K E + + K Sbjct: 383 QQQNNKIDDKEVEKLFEALIQLVDEDQSNKLESMQNASKFDWNKTQIKELVKSIKKRNSV 442 Query: 454 LEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQIT 513 L+ Q H+E + + E + + Q ++ E+ + K+ +K L +K++ ++ I+ Sbjct: 443 LQTQTHLEDQLKQYQEKSAEQLQQQQIGQGFIQSEIEE--KNQLIKQLQDKIRQQQQLIS 500 Query: 514 QLNDE---IDAANKNMIKVKSNHKLKLKQMQK--TIDNFSKVSDSNKEIVRLTEELHHLS 568 ++ ++ ++ +K + LK+ + K TI +K S ++I L E+ Sbjct: 501 NYIEQTKLLEETHQQSMKSQEREYLKMIEELKNNTILKSNKESFYEEKISSLQLEMERKI 560 Query: 569 QKVAEL---EEEKGNLQLHLVD--YDSGR--MIESDV-YKKMI-EMENLAETRLKAISLL 619 ++ E +EE+ +++L+ YD + + D+ YKK E ENL E +L+ Sbjct: 561 KEKEEFIKSKEEQQEKEIYLISEQYDKIKKDLENKDILYKKQQKEQENLFEQQLRQ---- 616 Query: 620 ESQKFDLVQELHILQQKY----DEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASK 675 E QK++ + L +KY + +E ++ +I+Q Q +Q+ E+++ + ++ L Sbjct: 617 ECQKYE--NTIKTLDEKYQYQIENLEKQVIEINQ-QKNQI--ELETQEKIKNLENLLKKN 671 Query: 676 KELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKI-SE 734 +E + + LK + E G I+ ++ +++ + +QN +Q+ ++ E + E I + Sbjct: 672 QEESQNL--LKQNLETYEGKIEQMQIKQQNEIEGIQNRLQDQ----NQKENQNKENIYQQ 725 Query: 735 LLAKINHEEQSKI-QTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRY 793 + +IN + + +I + IQ +D I+ E ++ S+ E+ +V+E R Sbjct: 726 EIEQINQDYKQQINEISQNFKEIIQRKDESIKQQEQKIQDQDSK--HQEKLQSVLEQHRL 783 Query: 794 SLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKE--- 850 LE K + +E + +++ Q E + L D+ ++++ EI + +E Sbjct: 784 ELESKEQSIKLLKEESSQYFTQEIQQNTESYEKQ--LEQKDQTYQQEINEINQKFQETMF 841 Query: 851 -----LQKKNQILLEENQNLQISLSDMQQ-HYNALVEKANRTDLA-ESESTKYQTQLRDL 903 ++++ Q + E +Q Q L +++ H N +K E + Y+ Q+ ++ Sbjct: 842 QKDELIKQQEQKIQELDQQYQGQLKTLEEYHKNKFQQKDEEYQKQLEQKDKDYKQQINEV 901 Query: 904 ESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNI--------E 955 N K + + +I Q++++I D+E++ Q++ KV E E++I + Sbjct: 902 NQNFKEVLEQKNEIIKQQEQKIHDIELKHQEQLQILAEQHKVELESKEQSIKLLKEESSQ 961 Query: 956 YVTQ-LEAQLQEYKNNIE----NLNMNVEELNKMNLELI---DKHVQK-----------Q 996 Y TQ L+ + + +K +E + N+ ++E+N+ E+I D +++ Q Sbjct: 962 YFTQELQQKDETHKKQLEQKDQDHNIQIDEINQKFKEIISQKDDQIKQQEQKILDLDLNQ 1021 Query: 997 QTQSPDYTEQYINEINKLNAL----LKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQ 1052 Q Q EQY NE+++ + L+QKDEE ++IN ++ ++ + L Q Sbjct: 1022 QQQLKSLEEQYKNELSQKDETNQKSLEQKDEE---YKEQINEINQNFKEILQQKDDSLKQ 1078 Query: 1053 FTTKLE----NMEEEMQRVSKQLLDSKQHNEELQILVREQDDQ--IKELKETKLTFEMNI 1106 K++ N +++++ + +Q + + N+E + EQ DQ IK++ E F+ + Sbjct: 1079 QELKIQDLDLNHQQKLKTLEEQHKNQLEQNDEAYSKLLEQKDQENIKQINEISQNFKEIL 1138 Query: 1107 PKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNT 1166 K + T++ + ++ + LK+QE++++++E+ L+ +S + + Sbjct: 1139 EKKD-----ETMKQLEYKVSDFE------------LKLQEQQKYLEEQHKLELESKEQSI 1181 Query: 1167 ELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISS 1226 +L K + EL D +Q+Q++Q + + ND + + +IS Sbjct: 1182 QL----LKEESNQYFTQELKQKDETHQKQLDQ--KDQDHIQVVND----ISYKFKEAISQ 1231 Query: 1227 AVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKI 1286 DQ ++ +++ +L +E + + + LS + ++ L+ + +++ N+I Sbjct: 1232 KDDQIKYQEEKIYNLNLNYQE-QLKSLQEQHNNLLSQKDETHQGQLEQIDLDHKQQINEI 1290 Query: 1287 VTMEQVTSLQNKLQDKEEHLRNLQEKYADV-INQIEILRSEIEDEKVAFXXXXXX----X 1341 + + +Q K++ L+ L++K D+ +N E L+S ++ KV Sbjct: 1291 -----SQNFKEIIQQKDDSLKQLEQKIQDLDLNHQEQLKSILDQHKVELESKEQSIKLLK 1345 Query: 1342 XXXXXXXXXDLRTENQSYKQMQEQSILN----INEENAQLKKSSXXXXXXXXXXXXRVND 1397 +L+ +++SY++ EQ + INE N K+ ++ND Sbjct: 1346 EESSQYFTQELQQKSESYEKQLEQKDQDYKQQINEINQNFKEVLEEKEENLKQQEQKLND 1405 Query: 1398 AEA------KVLELTHQLELKDSE-----IYQKTHEY-TITLTQRNDEFENVRQQL-VEY 1444 E K L H++EL+ E + +++ +Y T L Q+++ + +Q+ ++ Sbjct: 1406 IELKNQEQFKSLAEQHKVELESKEQSIKLLKEESSQYFTQELQQKDETHQKQLEQIDQDH 1465 Query: 1445 EKRIEDLTYE------------KESELAILRLKMHENANHYETMQKESEIERVKLIEELN 1492 +K+I+++ K+SE IL L +H ++++++ + E + ++L Sbjct: 1466 KKQIDEINQNFKEIISQKDDQIKQSESKILDLDLHYQ-QQLKSLEEQYKNEISQKDQDLK 1524 Query: 1493 VKITE-SVSLNKQVAELNKALEEEVAK----TNEMQTALENQEIEIVTLNDEITNL 1543 +I E ++ Q++ +++ L+EE+ + TN++ + + +++ +DE NL Sbjct: 1525 QQINEIQINYQNQISNVSQKLQEELIQNDQLTNQISLLQQIYDKQLLQKDDEYKNL 1580 Score = 150 bits (364), Expect = 3e-34 Identities = 264/1286 (20%), Positives = 559/1286 (43%), Gaps = 108/1286 (8%) Query: 212 EDTKQQMTKMQENFIAMEAEWKDE--KQRLLKDIESKDVRISSLEEANKLLEAARFEISL 269 +D KQQ+ ++ +NF + + KDE KQ+ K I+ +D + E+ +LE R E+ Sbjct: 732 QDYKQQINEISQNFKEI-IQRKDESIKQQEQK-IQDQDSKHQ--EKLQSVLEQHRLELES 787 Query: 270 EHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELT--KK 327 + + E+ +S E E+K + ++ EI + T +K Sbjct: 788 KEQSIKLLKEESSQYFTQEIQQNT----ESYEKQLEQKDQTYQQEINEINQKFQETMFQK 843 Query: 328 IELLEHLNCQIRQTNKELENKLATMGT--ESKAVSSPSKKGSPLISR-KSGRNTASKMKS 384 EL++ +I++ +++ + +L T+ ++K + L + K + +++ Sbjct: 844 DELIKQQEQKIQELDQQYQGQLKTLEEYHKNKFQQKDEEYQKQLEQKDKDYKQQINEVNQ 903 Query: 385 PWSQL---SSETLNQDTDKKINKNEIA---KLEMVIQSLNKDLVDKEYVISE-KDTXXXX 437 + ++ +E + Q ++KI+ E+ +L+++ + +L KE I K+ Sbjct: 904 NFKEVLEQKNEIIKQQ-EQKIHDIELKHQEQLQILAEQHKVELESKEQSIKLLKEESSQY 962 Query: 438 XXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVN 497 KD + QLE + + + +++ I++ +Q+KQ+ +I D++ Sbjct: 963 FTQELQQKDETHKK-QLEQKDQDHNIQIDEINQKFKEI--ISQKDDQIKQQ-EQKILDLD 1018 Query: 498 VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSN-HKLKLKQMQKTIDNFSKVSDSN-- 554 + ++LKS EEQ + D N+ ++ K +K ++ ++ + + D + Sbjct: 1019 LNQQ-QQLKSLEEQYKNELSQKDETNQKSLEQKDEEYKEQINEINQNFKEILQQKDDSLK 1077 Query: 555 -KEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRL 613 +E+ +L+H QK+ LEE+ N QL D + Y K++E ++ + + Sbjct: 1078 QQELKIQDLDLNH-QQKLKTLEEQHKN-QLEQND---------EAYSKLLEQKD--QENI 1124 Query: 614 KAISLLESQKFDLVQELHILQQKYDEVEDKLADIS-QLQSDQ-VCSEIKSVHLEEQIDAL 671 K I+ + SQ F + E + ++E K++D +LQ Q E + LE + ++ Sbjct: 1125 KQINEI-SQNFKEILEKK--DETMKQLEYKVSDFELKLQEQQKYLEEQHKLELESKEQSI 1181 Query: 672 SASKKEL-ALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAE 730 K+E + LK E + + D ++N + +E + D K E Sbjct: 1182 QLLKEESNQYFTQELKQKDETHQKQLDQKDQDHIQVVNDISYKFKEAISQKDDQIKYQEE 1241 Query: 731 KISELLAKINHEEQSK-IQTQFG--IDAKIQERDLYIENIESELSKYKSRICR-LEESIA 786 KI L +N++EQ K +Q Q + K + +E I+ + + + I + +E I Sbjct: 1242 KIYNL--NLNYQEQLKSLQEQHNNLLSQKDETHQGQLEQIDLDHKQQINEISQNFKEIIQ 1299 Query: 787 VMEDRRYSLERKADQLGSYLQEKQKAY-SEYTIQEDELVNRLAVLMDHDRVVEKQLLEIE 845 +D LE+K L QE+ K+ ++ ++ + + +L + Q L+ + Sbjct: 1300 QKDDSLKQLEQKIQDLDLNHQEQLKSILDQHKVELESKEQSIKLLKEESSQYFTQELQQK 1359 Query: 846 HENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLES 905 E+ E Q L +++Q+ + ++++ Q++ ++E+ +L + E +L++ E Sbjct: 1360 SESYEKQ-----LEQKDQDYKQQINEINQNFKEVLEEKEE-NLKQQEQKLNDIELKNQEQ 1413 Query: 906 NLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQ-LEAQL 964 K + +H+ + K++ I+ L+ E + ++ K +E ++K +E + Q + Q+ Sbjct: 1414 -FKSLAEQHKVELESKEQSIKLLKEESSQYFTQELQQK---DETHQKQLEQIDQDHKKQI 1469 Query: 965 QEYKNNI-ENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDE 1023 E N E ++ +++ + +++D + QQ Q EQY NEI+ QKD+ Sbjct: 1470 DEINQNFKEIISQKDDQIKQSESKILDLDLHYQQ-QLKSLEEQYKNEIS-------QKDQ 1521 Query: 1024 EIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSK--QHNEEL 1081 + L Q+IN Q++Y + +S+ KL + + + + ++ + +Q+ D + Q ++E Sbjct: 1522 D---LKQQINEIQINYQNQISNVSQKLQEELIQNDQLTNQISLL-QQIYDKQLLQKDDEY 1577 Query: 1082 QILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXX 1141 + L+ E + + K+ + E I++ T+E V Sbjct: 1578 KNLILEISENHLRMIINKMNLIITNFNNE-QILNLTLENEQLREQIVTENKVTAQQQQIY 1636 Query: 1142 LKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKS 1201 +K ++F Q++ L Q+ KL E T + + L EQI++LK Sbjct: 1637 IK----DDFNQQQEQLSNQNHKLINEDSNNQTNT-DFQIIEENLKSLINEQNEQISELKQ 1691 Query: 1202 K----LEQLNTENDNLLSTVAELRSSISSAVD--QRGFEIAELWKQHLAQREADFQKTEH 1255 K + + N S EL+S +D + +E + Q+ ++ + + ++ Sbjct: 1692 KDFDNQNIIESLKQNFESKQQELQSKYQGQIDACMKDYEDEKDKMQNQFKQVQNDLEEKY 1751 Query: 1256 ELRV-QLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDK-EEHLRNLQEKY 1313 +L + +L SK + ++SS Q ++ + Q T L+ +Q + EE L+ + Sbjct: 1752 KLEIFELLETISKLRFQIQDIESSLQNTNAELFS--QQTKLKQIIQLQFEEQLKKQASEK 1809 Query: 1314 ADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRT---ENQSYKQMQEQSILNI 1370 ++I+ E LR + ++ + DL+ E + + + N Sbjct: 1810 DEIISNFEKLRYQY-NQTLQLNQQKDSEIQEQKSFIEDLKKNIDETNQLLSLPKSTYNNF 1868 Query: 1371 NEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQR 1430 + N + +K + D +L+L +QL LK+SEIY ++ +QR Sbjct: 1869 KQLNIKFEKEKVDQTGLTQNTAKELQD---NLLQLRNQLILKESEIYSLRLQFIDANSQR 1925 Query: 1431 NDEFENVRQQLVEYEKRIEDL-TYEK 1455 + F V+ + E + E L TY++ Sbjct: 1926 LNYFYQVQNYIKEMKLMSEKLQTYDQ 1951 Score = 132 bits (318), Expect = 1e-28 Identities = 185/921 (20%), Positives = 401/921 (43%), Gaps = 80/921 (8%) Query: 680 LVIENLKLDKEQLYGTIKDLENDK-EDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAK 738 L++ N++LDK + + +D + K + + + + +Q+ +K++ EK+ E L + Sbjct: 344 LILRNIQLDKFTAFLSQEDEKKIKYRNSIAQKEQQLQQQQQQNNKIDDKEVEKLFEALIQ 403 Query: 739 INHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERK 798 + E+QS +K I+ + + K S L+ + + + E+ Sbjct: 404 LVDEDQSNKLESMQNASKFDWNKTQIKELVKSIKKRNS---VLQTQTHLEDQLKQYQEKS 460 Query: 799 ADQLGSYLQEKQKAYSEYTIQE-DELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQI 857 A+QL Q+ + + + I+E ++L+ +L D++ ++Q L N Q K Sbjct: 461 AEQLQQ--QQIGQGFIQSEIEEKNQLIKQL-----QDKIRQQQQL---ISNYIEQTK--- 507 Query: 858 LLEENQNLQISLSDMQQHYNALVEK-ANRTDLAESESTKYQTQLRDLESNLKRITHEHQT 916 LLEE Q S+ ++ Y ++E+ N T L ++ + Y+ ++ L+ ++R E + Sbjct: 508 LLEETH--QQSMKSQEREYLKMIEELKNNTILKSNKESFYEEKISSLQLEMERKIKEKEE 565 Query: 917 LIVQKKKEIED---LEIEFNTQIESAIRDKKVLNEKYEKNIE--YVTQLEAQLQEYKNNI 971 I K+++ E L E +I+ + +K +L +K +K E + QL + Q+Y+N I Sbjct: 566 FIKSKEEQQEKEIYLISEQYDKIKKDLENKDILYKKQQKEQENLFEQQLRQECQKYENTI 625 Query: 972 ENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQK 1031 + L +E + +E ++K V + Q + +I L LLK+ EE Sbjct: 626 KTL----DEKYQYQIENLEKQVIEINQQKNQIELETQEKIKNLENLLKKNQEE------- 674 Query: 1032 INNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQ-RVSKQLLDSKQHNEEL--QILVREQ 1088 +Q + YE K+ Q K +N E +Q R+ Q Q+ E + Q + + Sbjct: 675 ---SQNLLKQNLETYEGKIEQMQIKQQNEIEGIQNRLQDQNQKENQNKENIYQQEIEQIN 731 Query: 1089 DDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEE 1148 D +++ E F+ I + + I E D ++ L+++ +E Sbjct: 732 QDYKQQINEISQNFKEIIQRKDESIKQQ--EQKIQDQDSKHQEKLQSVLEQHRLELESKE 789 Query: 1149 EFIQERSVLQEQSAKLNT-ELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLN 1207 + I+ +L+E+S++ T E+Q+ E+ +L D Q++IN++ K ++ Sbjct: 790 QSIK---LLKEESSQYFTQEIQQ------NTESYEKQLEQKDQTYQQEINEINQKFQETM 840 Query: 1208 TENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESK 1267 + D L + + I Q ++ L + H + FQ+ + E + QL + Sbjct: 841 FQKDEL---IKQQEQKIQELDQQYQGQLKTLEEYH----KNKFQQKDEEYQKQLEQKDKD 893 Query: 1268 YEQLLDSVQSSTQ---EETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILR 1324 Y+Q ++ V + + E+ N+I+ ++ +L+ +E+ L+ L E++ + E Sbjct: 894 YKQQINEVNQNFKEVLEQKNEIIKQQEQKIHDIELKHQEQ-LQILAEQHKVELESKEQSI 952 Query: 1325 SEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYK--QMQEQSILNINEENAQLKKSSX 1382 +++E + + + ++ + + ++ ++ I++++ Q+K+ Sbjct: 953 KLLKEESSQYFTQELQQKDETHKKQLEQKDQDHNIQIDEINQKFKEIISQKDDQIKQQEQ 1012 Query: 1383 XXXXXXXXXXXRVNDAEAKVL-ELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQ- 1440 ++ E + EL+ + E + QK EY + + N F+ + QQ Sbjct: 1013 KILDLDLNQQQQLKSLEEQYKNELSQKDETNQKSLEQKDEEYKEQINEINQNFKEILQQK 1072 Query: 1441 ---LVEYEKRIEDLTYEKESELAIL----RLKMHENANHYETMQKESEIERVKLIEELNV 1493 L + E +I+DL + +L L + ++ +N Y + ++ + E +K I E++ Sbjct: 1073 DDSLKQQELKIQDLDLNHQQKLKTLEEQHKNQLEQNDEAYSKLLEQKDQENIKQINEISQ 1132 Query: 1494 KITESV-SLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSS 1552 E + ++ + +L + + K E Q LE Q + L + ++Q + S+ Sbjct: 1133 NFKEILEKKDETMKQLEYKVSDFELKLQEQQKYLEEQ--HKLELESKEQSIQLLKEESNQ 1190 Query: 1553 KIQKHVSFASDTKQGRDEQLD 1573 + + +T Q + +Q D Sbjct: 1191 YFTQELKQKDETHQKQLDQKD 1211 Score = 109 bits (263), Expect = 5e-22 Identities = 147/784 (18%), Positives = 341/784 (43%), Gaps = 39/784 (4%) Query: 807 QEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLE--IEHENKELQKKNQILLEENQN 864 +++ KA E + E + + + +D Q E I++ N QK+ Q+ ++ QN Sbjct: 327 RDQYKAIQEINVDEFQRLILRNIQLDKFTAFLSQEDEKKIKYRNSIAQKEQQLQQQQQQN 386 Query: 865 LQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITH--EHQTLIVQKK 922 +I ++++ + AL++ + + ES + ++ ++ +K + + + ++Q + Sbjct: 387 NKIDDKEVEKLFEALIQLVDEDQSNKLESMQNASKFDWNKTQIKELVKSIKKRNSVLQTQ 446 Query: 923 KEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELN 982 +ED ++ + ++ +++ + IE QL QLQ+ + L N E Sbjct: 447 THLEDQLKQYQEKSAEQLQQQQIGQGFIQSEIEEKNQLIKQLQDKIRQQQQLISNYIEQT 506 Query: 983 KMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSM 1042 K+ L + H Q ++Q +Y + I E+ K N +LK E +KI++ Q+ Sbjct: 507 KL---LEETHQQSMKSQEREYLKM-IEEL-KNNTILKSNKESF--YEEKISSLQLEMERK 559 Query: 1043 VSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTF 1102 + + E + +K E E+E+ +S+Q K+ E IL ++Q + + L E +L Sbjct: 560 IKEKEEFI---KSKEEQQEKEIYLISEQYDKIKKDLENKDILYKKQQKEQENLFEQQLRQ 616 Query: 1103 EMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSA 1162 E K E I + E N++ ++++ +E+ ++L++ Sbjct: 617 ECQ--KYEN-TIKTLDEKYQYQIENLEKQVIEINQQKNQIELETQEKIKNLENLLKKNQE 673 Query: 1163 KLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLN-TENDNLLSTVAELR 1221 + L++ LET ++ + Q +I ++++L+ N EN N + + Sbjct: 674 ESQNLLKQ------NLETYEGKIEQMQIKQQNEIEGIQNRLQDQNQKENQNKENIYQQEI 727 Query: 1222 SSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDS--VQSST 1279 I+ Q+ EI++ +K+ + +++ ++ E +++ Q S + K + +L+ ++ + Sbjct: 728 EQINQDYKQQINEISQNFKEIIQRKDESIKQQEQKIQDQDSKHQEKLQSVLEQHRLELES 787 Query: 1280 QEETNKIVTMEQVTSLQNKL-QDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXX 1338 +E++ K++ E ++ Q+ E + + L++K D Q EI + ++ F Sbjct: 788 KEQSIKLLKEESSQYFTQEIQQNTESYEKQLEQK--DQTYQQEINEINQKFQETMFQKDE 845 Query: 1339 XXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDA 1398 D + + Q K ++E +++ + +K VN Sbjct: 846 LIKQQEQKIQELDQQYQGQ-LKTLEEYHKNKFQQKDEEYQKQLEQKDKDYKQQINEVNQN 904 Query: 1399 EAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESE 1458 +VLE +++ +K E QK H+ I L + Q VE E + + + KE Sbjct: 905 FKEVLEQKNEI-IKQQE--QKIHD--IELKHQEQLQILAEQHKVELESKEQSIKLLKEES 959 Query: 1459 LAILRLKMHE-NANHYETMQKESEIERVKLIEELNVKITESVS-LNKQVAELNKALEEEV 1516 ++ + + H + ++++ + ++ I+E+N K E +S + Q+ + + + + Sbjct: 960 SQYFTQELQQKDETHKKQLEQKDQDHNIQ-IDEINQKFKEIISQKDDQIKQQEQKILDLD 1018 Query: 1517 AKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTM 1576 + +LE Q ++ DE TN +++ + ++ + K+ ++ D+ Sbjct: 1019 LNQQQQLKSLEEQYKNELSQKDE-TNQKSLEQKDEEYKEQINEINQNFKEILQQKDDSLK 1077 Query: 1577 NKEL 1580 +EL Sbjct: 1078 QQEL 1081 Score = 87.0 bits (206), Expect = 4e-15 Identities = 181/927 (19%), Positives = 408/927 (44%), Gaps = 89/927 (9%) Query: 212 EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRI-SSLEEANKLLE--AARFEIS 268 E K Q+ + E + + + E + + +I I +E K LE + FE+ Sbjct: 1099 EQHKNQLEQNDEAYSKLLEQKDQENIKQINEISQNFKEILEKKDETMKQLEYKVSDFELK 1158 Query: 269 LEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKI 328 L+ + E EQ L ++S + +E + +E ++ + I Sbjct: 1159 LQEQQKYLE-EQHKLELESKEQSIQLLKEESNQYFTQELKQKDETHQKQLDQKDQ--DHI 1215 Query: 329 ELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQ 388 +++ ++ + ++ + ++++ E K + L S + N K Q Sbjct: 1216 QVVNDISYKFKEAISQKDDQIKYQ--EEKIYNLNLNYQEQLKSLQEQHNNLLSQKDETHQ 1273 Query: 389 LSSETLNQDTDKKINKNEIAK-LEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDT 447 E + D D K NEI++ + +IQ + L E I + D + Sbjct: 1274 GQLEQI--DLDHKQQINEISQNFKEIIQQKDDSLKQLEQKIQDLDLNHQEQLKSILDQHK 1331 Query: 448 LIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQ-EQLKQELNDEIKDVN--VKDLIE- 503 + + + + + ++ S + + +E + Q EQ Q+ +I ++N K+++E Sbjct: 1332 VELESKEQSIKLLKEESSQYFTQELQQKSESYEKQLEQKDQDYKQQINEINQNFKEVLEE 1391 Query: 504 KLKSAEEQITQLNDEIDAANKNMIK-VKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTE 562 K ++ ++Q +LND I+ N+ K + HK++L+ +++I + +S++ + + Sbjct: 1392 KEENLKQQEQKLND-IELKNQEQFKSLAEQHKVELESKEQSIKLLKE--ESSQYFTQELQ 1448 Query: 563 ELHHLSQKVAELEEEKGNLQLHLVDYDSGRMI--ESDVYK----KMIEMENLAETRLKAI 616 + QK E ++ Q+ ++ + +I + D K K+++++ + +LK Sbjct: 1449 QKDETHQKQLEQIDQDHKKQIDEINQNFKEIISQKDDQIKQSESKILDLDLHYQQQLK-- 1506 Query: 617 SLLESQKFDLVQELHILQQKYDEVE----DKLADISQ------LQSDQVCSEIKSVH--L 664 SL E K ++ Q+ L+Q+ +E++ ++++++SQ +Q+DQ+ ++I + Sbjct: 1507 SLEEQYKNEISQKDQDLKQQINEIQINYQNQISNVSQKLQEELIQNDQLTNQISLLQQIY 1566 Query: 665 EEQIDALSASKKELALVI-EN-LKLDKEQLYGTIKDLENDKEDIMN-KLQNYIQENMDLT 721 ++Q+ K L L I EN L++ ++ I + N E I+N L+N +T Sbjct: 1567 DKQLLQKDDEYKNLILEISENHLRMIINKMNLIITNFNN--EQILNLTLENEQLREQIVT 1624 Query: 722 DKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESEL--SKYKSRIC 779 + K++A++ + +++Q ++ Q I E N + ++ KS I Sbjct: 1625 EN--KVTAQQQQIYIKDDFNQQQEQLSNQN--HKLINEDSNNQTNTDFQIIEENLKSLIN 1680 Query: 780 RLEESIAVMEDRRYSLERKADQLGSYLQEKQKAY-SEYTIQEDELVNRLAVLMDHDRVVE 838 E I+ ++ + + + + L + KQ+ S+Y Q D A + D++ + Sbjct: 1681 EQNEQISELKQKDFDNQNIIESLKQNFESKQQELQSKYQGQID------ACMKDYEDEKD 1734 Query: 839 KQLLEIEHENKELQKKNQI----LLEENQNLQISLSDMQQHYNALVEKANRTDLAESEST 894 K + + +L++K ++ LLE L+ + D++ ++ N ++ Sbjct: 1735 KMQNQFKQVQNDLEEKYKLEIFELLETISKLRFQIQDIESS----LQNTNAELFSQQTKL 1790 Query: 895 KYQTQLRDLESNLKRITHEHQTLI--VQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEK 952 K QL+ E LK+ E +I +K + + ++ N Q +S I+++K E +K Sbjct: 1791 KQIIQLQ-FEEQLKKQASEKDEIISNFEKLRYQYNQTLQLNQQKDSEIQEQKSFIEDLKK 1849 Query: 953 NIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEIN 1012 NI+ QL + + NN + LN+ E+ E +D+ Q T ++ + + Sbjct: 1850 NIDETNQLLSLPKSTYNNFKQLNIKFEK------EKVDQTGLTQNT-----AKELQDNLL 1898 Query: 1013 KLNALLKQKDEEIIALNQKI---NNAQVSYMSMVSDYESKLAQFTTKLENMEE-EMQRVS 1068 +L L K+ EI +L + N+ +++Y V +Y ++ + KL+ ++ ++Q++ Sbjct: 1899 QLRNQLILKESEIYSLRLQFIDANSQRLNYFYQVQNYIKEMKLMSEKLQTYDQSDVQQI- 1957 Query: 1069 KQLLDSKQHNEELQILVREQDDQIKEL 1095 + + E++++L + ++Q+ L Sbjct: 1958 -----TSYYEEKIKLLDQSYEEQMNRL 1979 Score = 45.2 bits (102), Expect = 0.015 Identities = 107/542 (19%), Positives = 214/542 (39%), Gaps = 48/542 (8%) Query: 212 EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271 + KQ +K+ + + + + K +++ +I KD + ++ N++ + +IS Sbjct: 1485 DQIKQSESKILDLDLHYQQQLKSLEEQYKNEISQKDQDLK--QQINEIQINYQNQISNVS 1542 Query: 272 SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELL 331 KL +EL Q KQ ++ E K I E + + I + Sbjct: 1543 QKLQEELIQNDQLTNQISLLQQIYDKQLLQKDDEYKNLILEISENHLRMIINKMNLI-IT 1601 Query: 332 EHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSS 391 N QI E E + TE+K + + I K N + + S + Sbjct: 1602 NFNNEQILNLTLENEQLREQIVTENKVTAQQQQ-----IYIKDDFN---QQQEQLSNQNH 1653 Query: 392 ETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQ 451 + +N+D++ + N + +++ ++L + ++ ISE Sbjct: 1654 KLINEDSNNQTNTD----FQIIEENLKSLINEQNEQISELKQKDFDNQNIIESLKQNFES 1709 Query: 452 LQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELND--EIKDVNVKDLIEKLKSAE 509 Q E Q +G + + ED + K+Q Q KQ ND E + + +L+E + Sbjct: 1710 KQQELQSKYQG-QIDACMKDYEDEKD--KMQNQFKQVQNDLEEKYKLEIFELLETISKLR 1766 Query: 510 EQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQ 569 QI + + N + ++ K ++ Q+Q + K + EI+ E+L + Sbjct: 1767 FQIQDIESSLQNTNAELFSQQTKLK-QIIQLQFE-EQLKKQASEKDEIISNFEKLRYQYN 1824 Query: 570 KVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISL-LESQKFDLVQ 628 + +L ++K + + D +++ + K +++ E +K D Sbjct: 1825 QTLQLNQQKDSEIQEQKSFIEDLKKNIDETNQLLSLPKSTYNNFKQLNIKFEKEKVD--- 1881 Query: 629 ELHILQQKYDEVEDKLADI-SQLQSDQVCSEIKSVHLEEQIDALSASK----------KE 677 + + Q E++D L + +QL + SEI S+ L+ IDA S KE Sbjct: 1882 QTGLTQNTAKELQDNLLQLRNQLILKE--SEIYSLRLQF-IDANSQRLNYFYQVQNYIKE 1938 Query: 678 LALVIENLKL----DKEQLYG----TIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSA 729 + L+ E L+ D +Q+ IK L+ E+ MN+L +++N D + S+ Sbjct: 1939 MKLMSEKLQTYDQSDVQQITSYYEEKIKLLDQSYEEQMNRLFQQLKQNQDKEQIAQSQSS 1998 Query: 730 EK 731 ++ Sbjct: 1999 QQ 2000 >UniRef50_A0CZI7 Cluster: Chromosome undetermined scaffold_32, whole genome shotgun sequence; n=3; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_32, whole genome shotgun sequence - Paramecium tetraurelia Length = 1837 Score = 160 bits (389), Expect = 3e-37 Identities = 223/1119 (19%), Positives = 506/1119 (45%), Gaps = 121/1119 (10%) Query: 481 VQEQLKQELNDEIK--DVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLK 538 +Q+Q++Q+L ++ + +K E L E+Q I +K ++V +N L LK Sbjct: 472 IQQQIQQQLAYALQCQGLVMKTFYENLTLKEQQ-----GAIQTVSKVQVQVDTNLNL-LK 525 Query: 539 QMQKTIDN-------FSKVSDS--NKEIVRLTE--ELHHLSQKVAELEEEKGNLQLHLVD 587 + +T+ N F + D N + V L + EL LS+ +L E+ + + D Sbjct: 526 DIVETVQNSLNERRQFQQQLDLQFNSQYVTLDKFKELETLSEYKEKLLSEQTQKLVFMED 585 Query: 588 YDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADI 647 + IE + +K+ E K + + + Q DL ++ L Q+ +L ++ Sbjct: 586 QI--KEIEKQILQKLEENGITFNENDKVVDVRDQQIQDLKTKITDLNQELQNSNQELKEL 643 Query: 648 SQLQSDQVCSEIKS-----VHLEEQIDA-LSASKKELALVIENLKLDKEQLYGTIKDLEN 701 S + S+QV +++ V+ +++I++ ++ +++ +N K L + L++ Sbjct: 644 S-INSEQVIQQLRFENQQIVNQKQEIESNYELTQTQISEFQDNSKQQIINLEQQLSQLQD 702 Query: 702 DKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERD 761 N+ Q Q+N DL K+E + I ++E+ K+ +D I + D Sbjct: 703 QNSQYSNQYQQLNQQNEDLKYKIENEEHQNKQLTQELIQNQEKLKL-----LDQIIVDND 757 Query: 762 LYIENIESELSKYKSRICRLEESI----AVMEDRRYSLERKADQLGSYLQEKQKAYSEYT 817 + I+ + +L+ Y+S I +L+++I A ++ + S+ + + + QE K +E T Sbjct: 758 IAIQEFKQQLTSYESIIIQLKKNINDQNANLQLNQQSISQLELENANLKQECSKQQNELT 817 Query: 818 IQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYN 877 + ++++ ++ L + ++ + QL + +N+ LQ +N +L + NQ +Q + + N Sbjct: 818 LMQEQVSLSMSKLENSEQELFSQLQLSQRDNQNLQNENSLLSKANQEMQSEMDVLILELN 877 Query: 878 ALVEKANRTDLA-ESESTKYQTQL--RDLESNLKRITHE--HQTLIVQKKKEIEDLEIEF 932 + E T + + + KY+ ++ +S ++R T E +Q I Q+KK+ E L +F Sbjct: 878 SKTEDLQNTQIQLQQKQQKYEQEIIIYQQKSQIERSTLEKDYQEQIKQQKKDFELLLFQF 937 Query: 933 NTQIESAIR--DKKVLNEKYEKNIEYVTQLEAQLQ-EYKNNIENLNMNVEELNKMNLELI 989 NT+ + ++++L+ Y + E+Q Q E++ N+ N + E + LE + Sbjct: 938 NTKQSCDLNKLNQEILSLNYIIKEKETNNTESQSQQEFQINLLNQKIQKETQRALQLESL 997 Query: 990 DKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESK 1049 ++ Q+ + + ++ ++ I+ L L+ K I + N Y+S+ + E K Sbjct: 998 ---LEGQKNEFQEIQKEQMSSIDLLQKQLESKQAVIQETSDHYNQVHELYLSLQARMEQK 1054 Query: 1050 ----------LAQFTTKLENMEEEMQRVSKQLLDSKQHN-EELQILVREQDDQIKELKET 1098 + Q +KLE+ +E+Q++ ++++ + N + + +Q +++++ + Sbjct: 1055 DLVNSELKRDILQNKSKLESQTKEIQQLQQKVISIENENLQSRNTMEIQQQGKLQDMTQ- 1113 Query: 1099 KLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQ 1158 KL+ +M +T + + I ++D ++ L+ Q++ E + ++LQ Sbjct: 1114 KLSIKM---RTIEQLTAEKIN-LNDKIKEIECESNKNKQTICLLE-QQQHESQNQNNLLQ 1168 Query: 1159 EQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVA 1218 Q LN EL + K ++ L EL+ + V + K + +Q+ +N+ L ++ Sbjct: 1169 AQIQSLNNELNQ---KEQEIGFLQQELSKQNQVLDKSSEIYKKETDQMEIDNNILKKQLS 1225 Query: 1219 ELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSS 1278 + + I + + +L L +++ D +L++QL+ + +Q L+ Sbjct: 1226 DKQKDIHKLEQKLNATLNDL---QLKEQQID------QLKLQLNHLNTNLQQQLE----- 1271 Query: 1279 TQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXX 1338 +T + L+ ++Q +H+ + E+ + +++ ++++++ K A Sbjct: 1272 --------LTTKDNLLLKKEIQQLNQHIESQHEEIDQMRIELDQKQTQVDENKSAVKKLT 1323 Query: 1339 XXXXXXXXXXXXDL-RTENQSYKQMQEQ-SILNINEENAQLKKSSXXXXXXXXXXXXRVN 1396 L R E+Q K++QE L+I+++ Q K V Sbjct: 1324 KQLELEIKQYSLHLKRNEDQHKKEVQELVDQLDIHQKQLQQKDLI-------------VE 1370 Query: 1397 DAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKE 1456 +V L E K+ H+ + Q D+ ++ + + + + +E+ + + Sbjct: 1371 SLNKQVNGLQCAFETKED----LNHQTQKDIQQLKDKLKSDQNKFTKIIQSLENANNQLK 1426 Query: 1457 SELAILRLKMHENANHYETMQKESEI---------ERVKLIEELNVKITESVSLNKQVAE 1507 S+L ++ ENA+ Y+++QK++++ E+ L++E ++ + Q+ E Sbjct: 1427 SQLEESSHQIQENAHKYQSVQKQNDLQSIQFNEQQEKYTLLKEQFTRLESQMKQESQIRE 1486 Query: 1508 LNKALEEEVAK-TNEMQTALENQEIEIVTLNDEITNLQN 1545 + ++V K NE++ ++ ++ IV L + LQN Sbjct: 1487 QYSHIADKVTKENNELKQKIDKKQQIIVQLESAL--LQN 1523 Score = 131 bits (317), Expect = 1e-28 Identities = 230/1172 (19%), Positives = 527/1172 (44%), Gaps = 125/1172 (10%) Query: 476 NEIAKVQEQLKQEL-------NDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIK 528 ++I ++++Q+ Q+L N+ K V+V+D ++++ + +IT LN E+ +N+ + + Sbjct: 585 DQIKEIEKQILQKLEENGITFNENDKVVDVRD--QQIQDLKTKITDLNQELQNSNQELKE 642 Query: 529 VKSNHKLKLKQMQ---KTIDNFSKVSDSNKEIVR--LTEELHHLSQKVAELEEEKGNLQL 583 + N + ++Q++ + I N + +SN E+ + ++E + Q++ LE++ LQ Sbjct: 643 LSINSEQVIQQLRFENQQIVNQKQEIESNYELTQTQISEFQDNSKQQIINLEQQLSQLQD 702 Query: 584 HLVDYDSGRMI---ESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHI-------- 632 Y + +++ K IE E +L + +K L+ ++ + Sbjct: 703 QNSQYSNQYQQLNQQNEDLKYKIENEEHQNKQLTQELIQNQEKLKLLDQIIVDNDIAIQE 762 Query: 633 LQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSAS-KKELALVIENLKLDKEQ 691 +Q+ E + + + +DQ + + Q++ +A+ K+E + L L +EQ Sbjct: 763 FKQQLTSYESIIIQLKKNINDQNANLQLNQQSISQLELENANLKQECSKQQNELTLMQEQ 822 Query: 692 LYGTIKDLENDKEDIMNKLQNYIQENMDLTDK---LEKMSAEKISE---LLAKINHEEQS 745 + ++ LEN ++++ ++LQ ++N +L ++ L K + E SE L+ ++N + + Sbjct: 823 VSLSMSKLENSEQELFSQLQLSQRDNQNLQNENSLLSKANQEMQSEMDVLILELNSKTED 882 Query: 746 KIQTQFGIDAKIQ--ERDLYIENIESELSK------YKSRICRLEESIAVME---DRRYS 794 TQ + K Q E+++ I +S++ + Y+ +I + ++ ++ + + S Sbjct: 883 LQNTQIQLQQKQQKYEQEIIIYQQKSQIERSTLEKDYQEQIKQQKKDFELLLFQFNTKQS 942 Query: 795 LE-RKADQ----LGSYLQEKQKAYSEYTIQEDELVNRL--AVLMDHDRVVE-KQLLEIE- 845 + K +Q L ++EK+ +E Q++ +N L + + R ++ + LLE + Sbjct: 943 CDLNKLNQEILSLNYIIKEKETNNTESQSQQEFQINLLNQKIQKETQRALQLESLLEGQK 1002 Query: 846 HENKELQKKNQ----ILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQL- 900 +E +E+QK+ +L ++ ++ Q + + HYN + E + ++L Sbjct: 1003 NEFQEIQKEQMSSIDLLQKQLESKQAVIQETSDHYNQVHELYLSLQARMEQKDLVNSELK 1062 Query: 901 RDLESNLKRITHEHQTL--IVQKKKEIEDLEIEFNTQIESAIRDK-KVLNEKYEKNIEYV 957 RD+ N ++ + + + + QK IE+ ++ +E + K + + +K + + Sbjct: 1063 RDILQNKSKLESQTKEIQQLQQKVISIENENLQSRNTMEIQQQGKLQDMTQKLSIKMRTI 1122 Query: 958 TQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNAL 1017 QL A+ + I+ + + NK + L+++ QQ +S + +I LN Sbjct: 1123 EQLTAEKINLNDKIKEIECESNK-NKQTICLLEQ----QQHESQNQNNLLQAQIQSLNNE 1177 Query: 1018 LKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQ- 1076 L QK++EI L Q++ S + V D S++ + + + ME + + KQL D ++ Sbjct: 1178 LNQKEQEIGFLQQEL-----SKQNQVLDKSSEI--YKKETDQMEIDNNILKKQLSDKQKD 1230 Query: 1077 -HNEELQILVREQDDQIKELKETKLTFEMNIPKT-----------EGMIISSTIEPMSD- 1123 H E ++ D Q+KE + +L ++N T + +++ I+ ++ Sbjct: 1231 IHKLEQKLNATLNDLQLKEQQIDQLKLQLNHLNTNLQQQLELTTKDNLLLKKEIQQLNQH 1290 Query: 1124 -DANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAK---LNTELQECYTK----- 1174 ++ + + +V E + +++ + E K L+ + E K Sbjct: 1291 IESQHEEIDQMRIELDQKQTQVDENKSAVKKLTKQLELEIKQYSLHLKRNEDQHKKEVQE 1350 Query: 1175 -IIQLETLNTELTGHDVVNQ---EQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQ 1230 + QL+ +L D++ + +Q+N L+ E N + +L+ + S DQ Sbjct: 1351 LVDQLDIHQKQLQQKDLIVESLNKQVNGLQCAFETKEDLNHQTQKDIQQLKDKLKS--DQ 1408 Query: 1231 RGF-EIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQL-LDSVQSSTQEETNKIVT 1288 F +I + + Q ++ +++ H+++ ++S +Q L S+Q + Q+E ++ Sbjct: 1409 NKFTKIIQSLENANNQLKSQLEESSHQIQENAHKYQSVQKQNDLQSIQFNEQQEKYTLLK 1468 Query: 1289 MEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIE---DEKVAFXXXXXXXXXXX 1345 EQ T L+++++ + + ++E+Y+ + +++ +E++ D+K Sbjct: 1469 -EQFTRLESQMKQESQ----IREQYSHIADKVTKENNELKQKIDKKQQIIVQLESALLQN 1523 Query: 1346 XXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXX---RVNDAEAKV 1402 ++ + + + QE+ I +I ++ +L+ ++ D + + Sbjct: 1524 EETLKNVHDRAKEFCKQQEKEINDIKDQYLKLEAEHNAILSQNQEREDENEQMKDQKDQA 1583 Query: 1403 LELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAIL 1462 L H LE + ++ ++ E LT+ N+E + +Q+ E +K I L I Sbjct: 1584 LRQMHTLEDEIGKLKKELQEQHEKLTKSNNERSMLYKQIEEMQKDIAQLGGHNNPSQKIR 1643 Query: 1463 RLKMHENANHYETMQKESEIERV-KLIEELNVKITESVSLNKQVAELNKALEEEVAKTNE 1521 L + N +K E++ K IEE N K+ + N++ N + + +K + Sbjct: 1644 YLNTIKQENSCLKQEKLYLSEQLQKEIEEKN-KLLQQQQQNRK----NTDSDNQSSKLDM 1698 Query: 1522 MQTALENQEIEIVTLNDEITNLQNMVRASSSK 1553 + +ENQ LN+E+T L ++ S K Sbjct: 1699 QKLMVENQR-----LNNEMTKLNQILNLSGVK 1725 Score = 123 bits (296), Expect = 5e-26 Identities = 256/1347 (19%), Positives = 573/1347 (42%), Gaps = 125/1347 (9%) Query: 309 EIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSP 368 ++ E+ +A E+ +K L H++ + + T+ ES+ SS ++ + Sbjct: 163 QLSEEVCTNVAESLEVLQKGSLNRHISSTQMNIESSRSHSVFTIQLESRRQSSQTQVINH 222 Query: 369 LISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVI 428 SR + A + SQ+ E L + + INK+ + L VI SL +D + Sbjct: 223 RFSRFHFVDLAGSERQKQSQVQGERLREGCN--INKS-LHILGNVINSLVEDNQSYVHYR 279 Query: 429 SEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLK-- 486 K T + LIA +Q Q + E S + + V A++ E Sbjct: 280 DSKLTFLLKDSLGGNSRTHLIANIQQSQQFYQETLSTLMFSKRVKQVKNKARINEDESGN 339 Query: 487 -QELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTID 545 + L +EIK + ++L + + + +++ ++ I + L+L+ + Sbjct: 340 LESLKNEIKRLK-QELAKSVTTQQQKWESPKKFEQKQQQSFINEQFLQSLELESLMINDQ 398 Query: 546 NFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEM 605 N+ K+ + K + + E + E+E+ ++ + G+ +E + K +I++ Sbjct: 399 NYIKLEEILKCYLEQSTESE--TALFLEIEKYLNGIKQLKEGFQLGQQLEQQL-KFVIKL 455 Query: 606 ENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLE 665 +N + QK L Q +QQ +++ +LA Q Q + + +++ L+ Sbjct: 456 QNE-----------QIQKLKLNQSADDIQQ---QIQQQLAYALQCQGLVMKTFYENLTLK 501 Query: 666 EQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLE 725 EQ A+ K V NL L K+ + T+++ N++ +L DK + Sbjct: 502 EQQGAIQTVSKVQVQVDTNLNLLKD-IVETVQNSLNERRQFQQQLDLQFNSQYVTLDKFK 560 Query: 726 KMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESI 785 ++ E +SE K+ E+ K+ ++ +I+E + + I +L + ++ + Sbjct: 561 EL--ETLSEYKEKLLSEQTQKLVF---MEDQIKEIE---KQILQKLEENGITFNENDKVV 612 Query: 786 AVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVV-EKQLLEI 844 V + + L+ K L LQ + E +I ++++ +L ++ ++V +KQ +E Sbjct: 613 DVRDQQIQDLKTKITDLNQELQNSNQELKELSINSEQVIQQLR--FENQQIVNQKQEIES 670 Query: 845 EHENKELQ-------KKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQ 897 +E + Q K QI+ E Q Q L D Y+ ++ N+ ++E KY+ Sbjct: 671 NYELTQTQISEFQDNSKQQIINLEQQLSQ--LQDQNSQYSNQYQQLNQ----QNEDLKYK 724 Query: 898 TQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYV 957 + + E K++T E ++Q +++++ L+ + + AI++ K YE + Sbjct: 725 --IENEEHQNKQLTQE----LIQNQEKLKLLD-QIIVDNDIAIQEFKQQLTSYES---II 774 Query: 958 TQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNAL 1017 QL+ + + N++ ++ +L N L + KQQ + EQ ++KL Sbjct: 775 IQLKKNINDQNANLQLNQQSISQLELENANL-KQECSKQQNELTLMQEQVSLSMSKLENS 833 Query: 1018 LKQKDEEIIALNQKINNAQVSYMSMVS----DYESKLAQFTTKLENMEEEMQRVSKQLLD 1073 ++ ++ L+Q+ N + S++S + +S++ +L + E++Q QL Sbjct: 834 EQELFSQL-QLSQRDNQNLQNENSLLSKANQEMQSEMDVLILELNSKTEDLQNTQIQL-Q 891 Query: 1074 SKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXX 1133 KQ E +I++ +Q QI E + ++ I + + + + + +++ Sbjct: 892 QKQQKYEQEIIIYQQKSQI-ERSTLEKDYQEQIKQQKKDFELLLFQFNTKQSCDLNKLNQ 950 Query: 1134 XXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETL-NTELTGHDVVN 1192 +K ++E + +S + Q LN ++Q+ + +QLE+L + + Sbjct: 951 EILSLNYIIK-EKETNNTESQSQQEFQINLLNQKIQKETQRALQLESLLEGQKNEFQEIQ 1009 Query: 1193 QEQINQLKSKLEQLNT------ENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQR 1246 +EQ++ + +QL + E + + V EL S+ + ++Q+ +EL K+ + Q Sbjct: 1010 KEQMSSIDLLQKQLESKQAVIQETSDHYNQVHELYLSLQARMEQKDLVNSEL-KRDILQN 1068 Query: 1247 EADFQKTEHELR-VQLSAFESKYEQLLD----------SVQSSTQEETNKIVTMEQVTSL 1295 ++ + E++ +Q + E L +Q TQ+ + K+ T+EQ+T+ Sbjct: 1069 KSKLESQTKEIQQLQQKVISIENENLQSRNTMEIQQQGKLQDMTQKLSIKMRTIEQLTAE 1128 Query: 1296 QNKLQDKEEHL-----RN------LQEKYADVINQIEILRSEIE---DEKVAFXXXXXXX 1341 + L DK + + +N L+++ + NQ +L+++I+ +E Sbjct: 1129 KINLNDKIKEIECESNKNKQTICLLEQQQHESQNQNNLLQAQIQSLNNELNQKEQEIGFL 1188 Query: 1342 XXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAK 1401 L ++ YK+ +Q ++ N QL +ND + K Sbjct: 1189 QQELSKQNQVLDKSSEIYKKETDQMEIDNNILKKQLSDKQKDIHKLEQKLNATLNDLQLK 1248 Query: 1402 V-------LELTH-------QLEL--KDSEIYQKT-HEYTITLTQRNDEFENVRQQLVEY 1444 L+L H QLEL KD+ + +K + + +++E + +R +L + Sbjct: 1249 EQQIDQLKLQLNHLNTNLQQQLELTTKDNLLLKKEIQQLNQHIESQHEEIDQMRIELDQK 1308 Query: 1445 EKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNV-------KITE 1497 + ++++ + L L++ + + H + + + + E +L+++L++ K Sbjct: 1309 QTQVDENKSAVKKLTKQLELEIKQYSLHLKRNEDQHKKEVQELVDQLDIHQKQLQQKDLI 1368 Query: 1498 SVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKH 1557 SLNKQV L A E + ++ Q ++ + ++ + ++ T + + ++++++ Sbjct: 1369 VESLNKQVNGLQCAFETKEDLNHQTQKDIQQLKDKLKSDQNKFTKIIQSLENANNQLKSQ 1428 Query: 1558 VSFASDTKQGRDEQLDNTMNKELLDAV 1584 + +S Q + + + L ++ Sbjct: 1429 LEESSHQIQENAHKYQSVQKQNDLQSI 1455 Score = 87.4 bits (207), Expect = 3e-15 Identities = 147/818 (17%), Positives = 362/818 (44%), Gaps = 51/818 (6%) Query: 216 QQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLA 275 Q++ K Q + I + + + KQ +++ E+ D + + E L+A + L +S+L Sbjct: 1006 QEIQKEQMSSIDLLQKQLESKQAVIQ--ETSD-HYNQVHELYLSLQARMEQKDLVNSELK 1062 Query: 276 QELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLN 335 +++ Q L ++ I E ++ + ++EI +L ++ + L+ Sbjct: 1063 RDILQNKSKLESQTKEIQQLQQKVISI---ENENLQSRNTMEIQQQGKLQ---DMTQKLS 1116 Query: 336 CQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLN 395 ++R T ++L + + + K + S K I + S+ ++ Q ++LN Sbjct: 1117 IKMR-TIEQLTAEKINLNDKIKEIECESNKNKQTICLLEQQQHESQNQNNLLQAQIQSLN 1175 Query: 396 QDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLE 455 + ++K + EI L+ + N+ ++DK I +K+T K Q + Sbjct: 1176 NELNQK--EQEIGFLQQELSKQNQ-VLDKSSEIYKKETDQMEIDNNILKKQLSDKQKDIH 1232 Query: 456 HQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQL 515 + +L + + ++++ L L +++ +L+ K ++I QL Sbjct: 1233 KLEQKLNATLNDLQLKEQQIDQLKLQLNHLNTNLQQQLELTTKDNLLLK-----KEIQQL 1287 Query: 516 NDEIDAANKNMIKVKSNHKLKLKQMQKTID-NFSKVSDSNKEIVRLTEELHHLSQKVAEL 574 N I++ ++ + +++ ++L Q Q +D N S V K++ L + + L K E Sbjct: 1288 NQHIESQHEEIDQMR----IELDQKQTQVDENKSAVKKLTKQL-ELEIKQYSLHLKRNE- 1341 Query: 575 EEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENL-AETRLKAISLLESQKFDLVQEL-HI 632 ++ K +Q LVD + D+++K ++ ++L E+ K ++ L+ F+ ++L H Sbjct: 1342 DQHKKEVQ-ELVD-------QLDIHQKQLQQKDLIVESLNKQVNGLQCA-FETKEDLNHQ 1392 Query: 633 LQQKYDEVEDKLADISQLQSDQVCSEIKSVH--LEEQIDALSASKKELALVIENLKLDKE 690 Q+ +++DKL Q + ++ +++ + L+ Q++ S +E A ++++ + Sbjct: 1393 TQKDIQQLKDKLKS-DQNKFTKIIQSLENANNQLKSQLEESSHQIQENAHKYQSVQKQND 1451 Query: 691 QLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQ 750 L + + +K ++ + ++ M ++ + + I++ + K N+E + KI + Sbjct: 1452 -LQSIQFNEQQEKYTLLKEQFTRLESQMKQESQIREQYSH-IADKVTKENNELKQKIDKK 1509 Query: 751 FGIDAKIQERDLYIENIESELSKYKSRICRLEES-IAVMEDRRYSLERKADQLGSYLQEK 809 I +++ L E + C+ +E I ++D+ LE + + + S QE+ Sbjct: 1510 QQIIVQLESALLQNEETLKNVHDRAKEFCKQQEKEINDIKDQYLKLEAEHNAILSQNQER 1569 Query: 810 QKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISL 869 + + Q+D+ + ++ L D ++K+L E + + + +L ++ + +Q + Sbjct: 1570 EDENEQMKDQKDQALRQMHTLEDEIGKLKKELQEQHEKLTKSNNERSMLYKQIEEMQKDI 1629 Query: 870 SDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLE 929 + + H N +K + + E++ + + L L++ E L+ Q+++ ++ + Sbjct: 1630 AQLGGHNNP-SQKIRYLNTIKQENSCLKQEKLYLSEQLQKEIEEKNKLLQQQQQNRKNTD 1688 Query: 930 IEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMN-----VEELNKM 984 + N + ++ V N++ + + Q+ L KN + + ++ + + Sbjct: 1689 SD-NQSSKLDMQKLMVENQRLNNEMTKLNQI-LNLSGVKNRFSTIKGSDGDKIIQSVQLL 1746 Query: 985 NLELID-KHVQKQQTQSPDYTEQYINEINKLNALLKQK 1021 ELID K +Q+ + + + K ++KQK Sbjct: 1747 IQELIDCKQEIQQRNKDQEGKNLKYQTMEKDLLVMKQK 1784 Score = 48.0 bits (109), Expect = 0.002 Identities = 78/409 (19%), Positives = 167/409 (40%), Gaps = 38/409 (9%) Query: 1199 LKSKLEQLNT-ENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHEL 1257 +K+ E L E + TV++++ + + ++ +I E + L +R Q+ + + Sbjct: 491 MKTFYENLTLKEQQGAIQTVSKVQVQVDTNLNLLK-DIVETVQNSLNERRQFQQQLDLQF 549 Query: 1258 RVQLSAFES--KYEQLLDSVQSSTQEETNKIVTME-QVTSLQNK-LQDKEEH--LRNLQE 1311 Q + + E L + + E+T K+V ME Q+ ++ + LQ EE+ N + Sbjct: 550 NSQYVTLDKFKELETLSEYKEKLLSEQTQKLVFMEDQIKEIEKQILQKLEENGITFNEND 609 Query: 1312 KYADVINQ-IEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQ---EQSI 1367 K DV +Q I+ L+++I D +L+ NQ K++ EQ I Sbjct: 610 KVVDVRDQQIQDLKTKITD------------------LNQELQNSNQELKELSINSEQVI 651 Query: 1368 LNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITL 1427 + EN Q+ ++++ + + LE + S++ + +Y+ Sbjct: 652 QQLRFENQQIVNQKQEIESNYELTQTQISEFQDNSKQQIINLEQQLSQLQDQNSQYSNQY 711 Query: 1428 TQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKL 1487 Q N + E+++ ++ E + + LT E ++ E + + +++I + Sbjct: 712 QQLNQQNEDLKYKIENEEHQNKQLTQEL--------IQNQEKLKLLDQIIVDNDIAIQEF 763 Query: 1488 IEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMV 1547 ++L + + L K + + N L+ ++++ N + E +E+T +Q V Sbjct: 764 KQQLTSYESIIIQLKKNINDQNANLQLNQQSISQLELENANLKQECSKQQNELTLMQEQV 823 Query: 1548 RASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDLAMYML 1596 S SK++ Q N N+ L + E+ M +L Sbjct: 824 SLSMSKLENSEQELFSQLQLSQRDNQNLQNENSLLSKANQEMQSEMDVL 872 >UniRef50_Q59K46 Cluster: Likely vesicular transport factor Uso1p; n=1; Candida albicans|Rep: Likely vesicular transport factor Uso1p - Candida albicans (Yeast) Length = 1880 Score = 160 bits (389), Expect = 3e-37 Identities = 240/1138 (21%), Positives = 481/1138 (42%), Gaps = 106/1138 (9%) Query: 470 TNTEDVN-EIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIK 528 T ED E+AK+QE K LN++ V L +K+ ++ ++ + +K Sbjct: 774 TKLEDKEQELAKIQEDHKS-LNEKFL-VTANSLCG-IKARTKESETISGPDQQELQEALK 830 Query: 529 VKSNHKLKLKQMQKTIDNFSKVSDSNKE-IVRLTEELHHLSQKVAELE-------EEKGN 580 + + LKQ+++ +D+ + ++ I +T +L HL + +E E E N Sbjct: 831 KGNTSESTLKQLKEKLDSTEQAKKKLEDGINNMTRDLFHLKKSKSEAETQIKQREREFKN 890 Query: 581 LQLHLVDYDSGRMIE-SDVYKKMIEM-ENLAETRLKAISLLESQKFD---LVQELHILQQ 635 L + ++ +++ K E + + E K SL E KF+ L ++L ++ Sbjct: 891 LTYEFENTKKDYELQINNLNKSNNEFKQKINELSKKIESLTEDNKFNAKQLEEKLRDTEE 950 Query: 636 KYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGT 695 + + DKL S +D + KS EE + A + L I+NL+ + ++ Sbjct: 951 NNEHLMDKLRSASVAYND--LKKAKSESEEETVKA-KEELETLTSKIDNLEKELKEQQSK 1007 Query: 696 IKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAE---KISELLAKINHEEQSKIQTQFG 752 +LE ++I + +E D ++K + E + SEL+ K+ E+ Sbjct: 1008 KNELEGQLQNITDSTNEKFKELEDELKSIKKSNKEISSQNSELIQKLEKTEKDLQAKDEE 1067 Query: 753 IDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKA 812 ID E I+N+ SE+S +S++ EES + +D SL + +K Sbjct: 1068 IDKLKAETKSNIDNLNSEISSLQSKLKEAEESHSSTKDEHSSLS----------ENLKKL 1117 Query: 813 YSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDM 872 EY + ++ +L+ ++ + K EIE + K + + ++ + +D+ Sbjct: 1118 KEEYENTKTSMIAKLSAKIEEHK---KATDEIETKTKHITDLQEEHAKQKSQFESERNDI 1174 Query: 873 QQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEI-EDLEIE 931 + + +++AN+ +L+++ + E N K T E + ++ I ED Sbjct: 1175 KSN----LDEANK-ELSDNREKLSNLEKEKTELNNKLKTQEEKISDLETSVAISEDKSKS 1229 Query: 932 FNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDK 991 IE R+K L ++N E + + + QLQ + + L +++L + + I+ Sbjct: 1230 LKHDIEDLKREKIKLETTLKENEETMFEKKEQLQVVNDKCKELEACLKKLTETKEKEIND 1289 Query: 992 HVQKQQTQSPDYTEQYINEINKLNALLK----QKDEEIIALNQKINNAQVSYMSMVSDYE 1047 ++K + D+ E KL+ L++ + ++ +I LN++I + V D + Sbjct: 1290 LIRKLEAAKSDHD----TERKKLSLLIEDTKSESEKNVIKLNEQIEKLKGEREKEVRDIQ 1345 Query: 1048 SKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIP 1107 S+LA TT E ++ + +V K+ D ++ N+E ++++ + +K KE L + Sbjct: 1346 SQLAAKTTDWEKIKTTLDKVLKEKSDLEKTNKESVDTLKKEVENLK--KEISLLEDQK-- 1401 Query: 1108 KTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEE--EFIQERSVLQEQSAKLN 1165 K + + +N+D LK E E E + LQ+ + L Sbjct: 1402 KDDTTKYKELAAQLETKTSNLDSTTMELEKTELELKKVRNELTEATSELTKLQDNNQSLT 1461 Query: 1166 TELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSIS 1225 E+++ + + + + E+ G+ Q ++L+ L+ + +E N + + +S+ Sbjct: 1462 EEIEKTKAALTK-SSKDLEVCGN------QKSELQDSLKSVKSELKNFENKYNQETTSLK 1514 Query: 1226 SAVDQRGFEIAELW---KQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEE 1282 ++++ EI L K +++ E + + + K + L + S + Sbjct: 1515 DEIEEKQKEIVTLQTELKDRISEVEKERAMLSENSETVIKEYSDKIKSLESKINSIKENH 1574 Query: 1283 TNKIVTM-EQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXX 1341 + +I T EQ TSL+ + + + Q + D NQ++ L++ +E Sbjct: 1575 SKEITTHNEQKTSLKQDIAKLSQDHESAQTQLEDKENQLKELKASLEKHNTE-------- 1626 Query: 1342 XXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAK 1401 + +N K++ E +I ++ E + + +D E+K Sbjct: 1627 ------SATSIEEKNNQIKELSE-TIKSLKTELKTSGDALKQSQKEYKTLKTKNSDTESK 1679 Query: 1402 VLELTHQLELKDSEIYQKTHEYTITLTQRN----DEFENVRQ-------QLVEYEKRIED 1450 + + +LE S++ Q E +T+R E E V+ +L K ++ Sbjct: 1680 LEKQLEELEKVKSDL-QTADEKLKGITEREIALKSELETVKNSGLSTTSELAALTKTVKS 1738 Query: 1451 LTYEKESELAILRLKMHENANHYETMQKESEI-ERVK-LIEELNVKITESVSLNKQVAEL 1508 L EKE EL L + Y +QK S+I E++K L +EL K + K++ EL Sbjct: 1739 LEKEKE-ELQFLSGNKSKELEDY--IQKHSDISEKLKALTDELKEKTKQFDDSKKKLTEL 1795 Query: 1509 N-------KALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVS 1559 K LE E +T++ + E ++ EIV LN E+ L+N + ++ + VS Sbjct: 1796 ENDLTSTKKELETEKTQTSKFKNLEERKDKEIVKLNKELELLKNDNSGAKKELSEKVS 1853 Score = 141 bits (342), Expect = 1e-31 Identities = 250/1208 (20%), Positives = 517/1208 (42%), Gaps = 114/1208 (9%) Query: 168 METTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIA 227 ++T +L+L +++ + + E+ +K ED +Q++ K+QE+ + Sbjct: 733 LDTKVLNLTKELQTEKENAESNDKELNEKIEKLTNLSTKLETKLEDKEQELAKIQEDHKS 792 Query: 228 MEAEWKDEKQRLLK-DIESKDVRISSLEEANKLLEAARFEISLEHS--KLAQELEQXXXX 284 + ++ L +K+ S + +L EA + + E + +L ++L+ Sbjct: 793 LNEKFLVTANSLCGIKARTKESETISGPDQQELQEALKKGNTSESTLKQLKEKLDSTEQA 852 Query: 285 XXXXXXXXXXLAKQSI---EPSCEEKTEIEEKGSLEIANMT---ELTKKIELLEHLNCQI 338 + + + E +T+I+++ E N+T E TKK L+ N + Sbjct: 853 KKKLEDGINNMTRDLFHLKKSKSEAETQIKQR-EREFKNLTYEFENTKKDYELQINN--L 909 Query: 339 RQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDT 398 ++N E + K+ + + ++++ +K + + K R+T + +L S ++ + Sbjct: 910 NKSNNEFKQKINELSKKIESLTEDNKFNAKQLEEKL-RDTEENNEHLMDKLRSASVAYND 968 Query: 399 DKKI---NKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLE 455 KK ++ E K + +++L + + E + E+ + K+ L QLQ Sbjct: 969 LKKAKSESEEETVKAKEELETLTSKIDNLEKELKEQQSK----------KNELEGQLQN- 1017 Query: 456 HQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQL 515 I TN E E+ + +K+ N EI N +LI+KL+ E+ + Sbjct: 1018 ----------ITDSTN-EKFKELEDELKSIKKS-NKEISSQN-SELIQKLEKTEKDLQAK 1064 Query: 516 NDEIDAANKNMIKVKSNHKLKLKQMQKTIDNF-SKVSDSNKEIVRLTEELHHLSQKVAEL 574 ++EID K+K+ K + + I + SK+ ++ + +E LS+ + +L Sbjct: 1065 DEEID-------KLKAETKSNIDNLNSEISSLQSKLKEAEESHSSTKDEHSSLSENLKKL 1117 Query: 575 EEEKGNLQLHLVDYDSGRMIE-----SDVYKKMIEMENLAETRLKAISLLESQKFDLVQE 629 +EE N + ++ S ++ E ++ K + +L E K S ES++ D+ Sbjct: 1118 KEEYENTKTSMIAKLSAKIEEHKKATDEIETKTKHITDLQEEHAKQKSQFESERNDIKSN 1177 Query: 630 LHILQQKYDEVEDKLADI----SQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENL 685 L ++ + +KL+++ ++L + E K LE + K L IE+L Sbjct: 1178 LDEANKELSDNREKLSNLEKEKTELNNKLKTQEEKISDLETSVAISEDKSKSLKHDIEDL 1237 Query: 686 KLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQS 745 K +K +L T+K+ E + +LQ + +L L+K++ K E+ I E + Sbjct: 1238 KREKIKLETTLKENEETMFEKKEQLQVVNDKCKELEACLKKLTETKEKEINDLIRKLEAA 1297 Query: 746 KIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSY 805 K D + ++ L IE+ +SE K + +L E I ++ R E++ + S Sbjct: 1298 KSDH----DTERKKLSLLIEDTKSESEK---NVIKLNEQIEKLKGER---EKEVRDIQSQ 1347 Query: 806 LQEKQKAYSEYTIQEDELVNRLAVLMDHDRV-VEKQLLEIEHENKEL-----QKKNQILL 859 L K + + D+++ + L ++ V+ E+E+ KE+ QKK+ Sbjct: 1348 LAAKTTDWEKIKTTLDKVLKEKSDLEKTNKESVDTLKKEVENLKKEISLLEDQKKDDTT- 1406 Query: 860 EENQNLQISLSDMQQHYNALVEKANRTDL----AESESTKYQTQLRDLESNLKRITHEHQ 915 + + L L + ++ + +T+L +E T+ ++L L+ N + +T E + Sbjct: 1407 -KYKELAAQLETKTSNLDSTTMELEKTELELKKVRNELTEATSELTKLQDNNQSLTEEIE 1465 Query: 916 TLIVQKKKEIEDLEIEFN--TQIESAIRDKKVLNEKYE-KNIEYVTQLEAQLQEYKNNIE 972 K +DLE+ N ++++ +++ K + +E K + T L+ +++E + I Sbjct: 1466 KTKAALTKSSKDLEVCGNQKSELQDSLKSVKSELKNFENKYNQETTSLKDEIEEKQKEIV 1525 Query: 973 NLNMNVEE-LNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQK 1031 L +++ ++++ E + +T +Y+++ + +K+N++ + +EI N++ Sbjct: 1526 TLQTELKDRISEVEKERAMLS-ENSETVIKEYSDKIKSLESKINSIKENHSKEITTHNEQ 1584 Query: 1032 INNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQ 1091 + + + D+ES Q K ++E + K +S EE ++E + Sbjct: 1585 KTSLKQDIAKLSQDHESAQTQLEDKENQLKELKASLEKHNTESATSIEEKNNQIKELSET 1644 Query: 1092 IKELKETKLTFEMNIPKTEG-MIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEF 1150 IK LK T+L KT G + S E + N D KV+ + + Sbjct: 1645 IKSLK-TEL-------KTSGDALKQSQKEYKTLKTKNSDTESKLEKQLEELEKVKSDLQT 1696 Query: 1151 IQER-SVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTE 1209 E+ + E+ L +EL+ K L T +EL + + + K +L+ L+ Sbjct: 1697 ADEKLKGITEREIALKSELET--VKNSGLST-TSELAAL-TKTVKSLEKEKEELQFLSGN 1752 Query: 1210 NDNLLSTVAELRSSISSAVDQRGFEIAELWKQ------HLAQREADFQKTEHELRVQLSA 1263 L + S IS + E+ E KQ L + E D T+ EL + + Sbjct: 1753 KSKELEDYIQKHSDISEKLKALTDELKEKTKQFDDSKKKLTELENDLTSTKKELETEKTQ 1812 Query: 1264 FESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEIL 1323 SK++ L + + +IV + + L+ D + L EK + + ++IEIL Sbjct: 1813 -TSKFKNL-------EERKDKEIVKLNK--ELELLKNDNSGAKKELSEKVSKLESEIEIL 1862 Query: 1324 RSEIEDEK 1331 ++ED+K Sbjct: 1863 SKKLEDKK 1870 Score = 129 bits (312), Expect = 5e-28 Identities = 183/979 (18%), Positives = 413/979 (42%), Gaps = 78/979 (7%) Query: 632 ILQQKYDEVEDKLADIS-QLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKE 690 I + ++E++ K+ +++ +LQ+++ +E L E+I+ L+ +L +E+ + + Sbjct: 725 ISYELFEELDTKVLNLTKELQTEKENAESNDKELNEKIEKLTNLSTKLETKLEDKEQELA 784 Query: 691 QLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQ 750 ++ K L N+K + I+ ++ + +++ E L K N E + Q + Sbjct: 785 KIQEDHKSL-NEKFLVTANSLCGIKARTKESETISGPDQQELQEALKKGNTSESTLKQLK 843 Query: 751 FGIDAKIQERDLY---IENIESELSKYKSRICRLEESIAVME----DRRYSLERKADQLG 803 +D+ Q + I N+ +L K E I E + Y E Sbjct: 844 EKLDSTEQAKKKLEDGINNMTRDLFHLKKSKSEAETQIKQREREFKNLTYEFENTKKDYE 903 Query: 804 SYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQ 863 + K+ +E+ + +EL ++ L + ++ KQL E + ++ ++ N+ L+++ + Sbjct: 904 LQINNLNKSNNEFKQKINELSKKIESLTEDNKFNAKQL---EEKLRDTEENNEHLMDKLR 960 Query: 864 NLQISLSDMQQHYNALVEKA-----------NRTDLAESESTKYQTQLRDLESNLKRITH 912 + ++ +D+++ + E+ ++ D E E + Q++ +LE L+ IT Sbjct: 961 SASVAYNDLKKAKSESEEETVKAKEELETLTSKIDNLEKELKEQQSKKNELEGQLQNITD 1020 Query: 913 EHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQ-EYKNNI 971 + + E++ ++ + N +I S + EK EK+++ + +L+ E K+NI Sbjct: 1021 STNEKFKELEDELKSIK-KSNKEISSQNSELIQKLEKTEKDLQAKDEEIDKLKAETKSNI 1079 Query: 972 ENLNMNVEELNKMNLELIDKHVQKQQTQSP------DYTEQYINEINKLNALLKQKDEEI 1025 +NLN + L E + H + S E+Y N + A L K EE Sbjct: 1080 DNLNSEISSLQSKLKEAEESHSSTKDEHSSLSENLKKLKEEYENTKTSMIAKLSAKIEEH 1139 Query: 1026 IALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILV 1085 +I + ++ + +QF ++ +++ + +K+L D+++ L+ Sbjct: 1140 KKATDEIETKTKHITDLQEEHAKQKSQFESERNDIKSNLDEANKELSDNREKLSNLEKEK 1199 Query: 1086 REQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQ 1145 E ++++K +E E ++ +E S +++ ++++ LK Sbjct: 1200 TELNNKLKTQEEKISDLETSVAISEDK--SKSLK------HDIEDLKREKIKLETTLKEN 1251 Query: 1146 EEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQ 1205 EE F +++ LQ + K EL+ C K+ + + +++IN L KLE Sbjct: 1252 EETMF-EKKEQLQVVNDKCK-ELEACLKKLTETK-------------EKEINDLIRKLEA 1296 Query: 1206 LNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFE 1265 +++D ++ L S ++ ++ E ++ +RE + + + +L + + +E Sbjct: 1297 AKSDHDTERKKLSLLIEDTKSESEKNVIKLNEQIEKLKGEREKEVRDIQSQLAAKTTDWE 1356 Query: 1266 SKYEQLLDSV--QSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEIL 1323 K + LD V + S E+TNK E V +L+ ++++ ++ + L+++ D + + L Sbjct: 1357 -KIKTTLDKVLKEKSDLEKTNK----ESVDTLKKEVENLKKEISLLEDQKKDDTTKYKEL 1411 Query: 1324 RSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXX 1383 +++E + +L+ + + + + + N L + Sbjct: 1412 AAQLETK----TSNLDSTTMELEKTELELKKVRNELTEATSE-LTKLQDNNQSLTEEIEK 1466 Query: 1384 XXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVE 1443 + + EL L+ SE+ ++Y T DE E ++++V Sbjct: 1467 TKAALTKSSKDLEVCGNQKSELQDSLKSVKSELKNFENKYNQETTSLKDEIEEKQKEIVT 1526 Query: 1444 YEKRIEDLTYEKESELAILRLKMHENANHYETMQK--ESEIERVK--LIEELNVKITESV 1499 + ++D E E E A+L Y K ES+I +K +E+ + Sbjct: 1527 LQTELKDRISEVEKERAMLSENSETVIKEYSDKIKSLESKINSIKENHSKEITTHNEQKT 1586 Query: 1500 SLNKQVAELNK-------ALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSS 1552 SL + +A+L++ LE++ + E++ +LE E T +E N + + Sbjct: 1587 SLKQDIAKLSQDHESAQTQLEDKENQLKELKASLEKHNTESATSIEEKNNQIKELSETIK 1646 Query: 1553 KIQKHVSFASDT-KQGRDE 1570 ++ + + D KQ + E Sbjct: 1647 SLKTELKTSGDALKQSQKE 1665 Score = 111 bits (268), Expect = 1e-22 Identities = 181/907 (19%), Positives = 394/907 (43%), Gaps = 89/907 (9%) Query: 720 LTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRIC 779 LTD + + + + H+ S+ + + + +E D + N+ EL K Sbjct: 694 LTDVYVNLVKDNFLRIKRALFHDPSSEPRGKISYEL-FEELDTKVLNLTKELQTEKENA- 751 Query: 780 RLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEK 839 E + + ++ L + +L + L++K++ ++ IQED L + V Sbjct: 752 --ESNDKELNEKIEKLTNLSTKLETKLEDKEQELAK--IQEDH-----KSLNEKFLVTAN 802 Query: 840 QLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQ 899 L I+ KE + I + Q LQ +L + L + + D E K + Sbjct: 803 SLCGIKARTKESET---ISGPDQQELQEALKKGNTSESTLKQLKEKLDSTEQAKKKLEDG 859 Query: 900 LRDLESNL---KRITHEHQTLIVQKKKEIEDLEIEF-NTQ--IESAIRDKKVLNEKYEKN 953 + ++ +L K+ E +T I Q+++E ++L EF NT+ E I + N ++++ Sbjct: 860 INNMTRDLFHLKKSKSEAETQIKQREREFKNLTYEFENTKKDYELQINNLNKSNNEFKQK 919 Query: 954 I-EYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDK---------HVQKQQTQSPDY 1003 I E ++E+ ++ K N + L + + + N L+DK ++K +++S + Sbjct: 920 INELSKKIESLTEDNKFNAKQLEEKLRDTEENNEHLMDKLRSASVAYNDLKKAKSESEEE 979 Query: 1004 TEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEE 1063 T + E+ L + + ++E+ K N + ++ K + +L+++++ Sbjct: 980 TVKAKEELETLTSKIDNLEKELKEQQSKKNELEGQLQNITDSTNEKFKELEDELKSIKKS 1039 Query: 1064 MQRVSKQLLDSKQHNEELQILVREQDDQIKELK-ETKLTFEMNIPKTEGMIISSTIEPMS 1122 + +S Q + Q E+ + ++ +D++I +LK ETK + N+ ISS + Sbjct: 1040 NKEISSQNSELIQKLEKTEKDLQAKDEEIDKLKAETKSNID-NLNSE----ISSLQSKLK 1094 Query: 1123 DDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQ---ECYTKIIQLE 1179 + + LK +EE + S++ + SAK+ + E TK + Sbjct: 1095 EAEESHSSTKDEHSSLSENLKKLKEEYENTKTSMIAKLSAKIEEHKKATDEIETKTKHIT 1154 Query: 1180 TLNTELTGHDVVNQEQINQLKSKLEQLNTE---NDNLLSTVAELRSSISSAVDQRGFEIA 1236 L E + + N +KS L++ N E N LS + + ++ +++ + + +I+ Sbjct: 1155 DLQEEHAKQKSQFESERNDIKSNLDEANKELSDNREKLSNLEKEKTELNNKLKTQEEKIS 1214 Query: 1237 ELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQ 1296 +L + +A E + +H++ + K E++ EET EQ+ + Sbjct: 1215 DL-ETSVAISEDKSKSLKHDIE------DLKREKIKLETTLKENEET-MFEKKEQLQVVN 1266 Query: 1297 NKLQDKEEHLRNLQE----KYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDL 1352 +K ++ E L+ L E + D+I ++E +S+ + E+ D Sbjct: 1267 DKCKELEACLKKLTETKEKEINDLIRKLEAAKSDHDTERKKLSLLIE-----------DT 1315 Query: 1353 RTENQSYKQMQEQSILNINEENAQLK-KSSXXXXXXXXXXXXRVNDAEAKVLELTHQLEL 1411 ++E+ E++++ +NE+ +LK + + D E ++ T L Sbjct: 1316 KSES-------EKNVIKLNEQIEKLKGEREKEVRDIQSQLAAKTTDWEK--IKTTLDKVL 1366 Query: 1412 KDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENAN 1471 K+ +KT++ ++ ++ E EN+++++ E + +D T K ELA N + Sbjct: 1367 KEKSDLEKTNKESVDTLKK--EVENLKKEISLLEDQKKDDT-TKYKELAAQLETKTSNLD 1423 Query: 1472 HYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEI 1531 +++E+E K+ EL TE+ S ++ + N++L EE+ KT T ++++ Sbjct: 1424 STTMELEKTELELKKVRNEL----TEATSELTKLQDNNQSLTEEIEKTKAALTK-SSKDL 1478 Query: 1532 EIV-----TLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPR 1586 E+ L D + ++++ ++ +K + + D + + +++ T+ EL D + Sbjct: 1479 EVCGNQKSELQDSLKSVKSELKNFENKYNQETTSLKDEIEEKQKEI-VTLQTELKDRISE 1537 Query: 1587 AELDLAM 1593 E + AM Sbjct: 1538 VEKERAM 1544 Score = 102 bits (244), Expect = 9e-20 Identities = 208/926 (22%), Positives = 389/926 (42%), Gaps = 74/926 (7%) Query: 67 VSKRIKEHRKATAELLGRPFVPGISESLANTLKQKEILMEKIKQY-KELSKRSSTTIVRX 125 + K +KE + EL G+ + I++S K+ E ++ IK+ KE+S ++S I + Sbjct: 997 LEKELKEQQSKKNELEGQ--LQNITDSTNEKFKELEDELKSIKKSNKEISSQNSELIQKL 1054 Query: 126 XXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNALSVLQVKMKIME---TTILDLQEKINEK 182 SN I ++ +S LQ K+K E ++ D ++E Sbjct: 1055 EKTEKDLQAKDEEIDKLKAETKSN-IDNLNSEISSLQSKLKEAEESHSSTKDEHSSLSEN 1113 Query: 183 DQII--EAKNKATTXXXXXXXXXXXXXXXXXE-DTK-QQMTKMQENFIAMEAEWKDEKQR 238 + + E +N T+ E +TK + +T +QE +++++ E+ Sbjct: 1114 LKKLKEEYENTKTSMIAKLSAKIEEHKKATDEIETKTKHITDLQEEHAKQKSQFESERND 1173 Query: 239 LLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQ 298 + +++ + +S E LE + E++ + +++ L K Sbjct: 1174 IKSNLDEANKELSDNREKLSNLEKEKTELNNKLKTQEEKISDLETSVAISEDKSKSL-KH 1232 Query: 299 SIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMG-TESK 357 IE EK ++E +L+ T KK E L+ +N + KELE L + T+ K Sbjct: 1233 DIEDLKREKIKLET--TLKENEETMFEKK-EQLQVVNDKC----KELEACLKKLTETKEK 1285 Query: 358 AVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSL 417 ++ +K L + KS +T K S L +T ++ I NE ++E + Sbjct: 1286 EINDLIRK---LEAAKSDHDTERKKLS---LLIEDTKSESEKNVIKLNE--QIEKLKGER 1337 Query: 418 NKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNE 477 K++ D + ++ K T K TL L+ + +E TN E V+ Sbjct: 1338 EKEVRDIQSQLAAKTTDWEKI------KTTL--DKVLKEKSDLEK-------TNKESVDT 1382 Query: 478 IAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKL 537 + K E LK+E++ + + KD K K Q+ +D+ + K + K Sbjct: 1383 LKKEVENLKKEIS--LLEDQKKDDTTKYKELAAQLETKTSNLDSTTMELEKTELELKKVR 1440 Query: 538 KQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESD 597 ++ + +K+ D+N+ + E+ K ++ E GN + L DS + ++S+ Sbjct: 1441 NELTEATSELTKLQDNNQSLTEEIEKTKAALTKSSKDLEVCGNQKSEL--QDSLKSVKSE 1498 Query: 598 VYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCS 657 + K N T LK + E QK ++V L+ + EVE + A +S+ S+ V Sbjct: 1499 L-KNFENKYNQETTSLKD-EIEEKQK-EIVTLQTELKDRISEVEKERAMLSE-NSETVIK 1554 Query: 658 EI--KSVHLEEQIDALSAS-KKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYI 714 E K LE +I+++ + KE+ E K L I L D E +L++ Sbjct: 1555 EYSDKIKSLESKINSIKENHSKEITTHNEQ----KTSLKQDIAKLSQDHESAQTQLEDKE 1610 Query: 715 QENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKY 774 + +L LEK + E + + K N++ + +T + +++ ++ + E Y Sbjct: 1611 NQLKELKASLEKHNTESATSIEEK-NNQIKELSETIKSLKTELKTSGDALKQSQKE---Y 1666 Query: 775 KSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTI---QEDELVNRLAVLM 831 K+ + ++ + +E + LE+ L + EK K +E I E E V + Sbjct: 1667 KTLKTKNSDTESKLEKQLEELEKVKSDLQT-ADEKLKGITEREIALKSELETVKNSGLST 1725 Query: 832 DHD-RVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAE 890 + + K + +E E +ELQ + +E ++ SD+ + AL ++ Sbjct: 1726 TSELAALTKTVKSLEKEKEELQFLSGNKSKELEDYIQKHSDISEKLKALTDELKEKTKQF 1785 Query: 891 SESTKYQTQLR-DLESNLKRI-THEHQTLIVQKKKEIEDLEI-EFNTQIESAIRD----K 943 +S K T+L DL S K + T + QT + +E +D EI + N ++E D K Sbjct: 1786 DDSKKKLTELENDLTSTKKELETEKTQTSKFKNLEERKDKEIVKLNKELELLKNDNSGAK 1845 Query: 944 KVLNEKYEKNIEYVTQLEAQLQEYKN 969 K L+EK K + L +L++ K+ Sbjct: 1846 KELSEKVSKLESEIEILSKKLEDKKS 1871 Score = 90.6 bits (215), Expect = 3e-16 Identities = 173/811 (21%), Positives = 337/811 (41%), Gaps = 70/811 (8%) Query: 50 RQIKFERAQKCLENAALVSKRIKEHRKATAELLGR-PFVPGISESLANTLKQKEILMEKI 108 +++K E A +S +I+EH+KAT E+ + + + E A Q E I Sbjct: 1115 KKLKEEYENTKTSMIAKLSAKIEEHKKATDEIETKTKHITDLQEEHAKQKSQFESERNDI 1174 Query: 109 K-QYKELSKRSSTTIVRXX--XXXXXXXXXXXXXQLGDVTHLSNTIKEKDNALSVLQVKM 165 K E +K S + Q ++ L ++ ++ L+ + Sbjct: 1175 KSNLDEANKELSDNREKLSNLEKEKTELNNKLKTQEEKISDLETSVAISEDKSKSLKHDI 1234 Query: 166 KIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENF 225 + ++ + L+ + E ++ + K + E ++++ + Sbjct: 1235 EDLKREKIKLETTLKENEETMFEKKEQLQVVNDKCKELEACLKKLTETKEKEINDLIRKL 1294 Query: 226 IAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELE-QXXXX 284 A +++ E+++L IE D + S + KL E ++ E K ++++ Q Sbjct: 1295 EAAKSDHDTERKKLSLLIE--DTKSESEKNVIKLNEQIE-KLKGEREKEVRDIQSQLAAK 1351 Query: 285 XXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKE 344 L K E S EKT E +L+ + L K+I LLE KE Sbjct: 1352 TTDWEKIKTTLDKVLKEKSDLEKTNKESVDTLK-KEVENLKKEISLLEDQKKDDTTKYKE 1410 Query: 345 LENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINK 404 L +L T + + + +K + K RN ++ S ++L QD ++ + + Sbjct: 1411 LAAQLETKTSNLDSTTMELEKTE--LELKKVRNELTEATSELTKL------QDNNQSLTE 1462 Query: 405 NEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPS 464 EI K + + +KDL E ++K K E++ + E S Sbjct: 1463 -EIEKTKAALTKSSKDL---EVCGNQKSELQDSL------KSVKSELKNFENKYNQETTS 1512 Query: 465 LIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANK 524 L +++ E K L+ EL D I +V K+ +++E I + +D+I + Sbjct: 1513 L------KDEIEEKQKEIVTLQTELKDRISEVE-KERAMLSENSETVIKEYSDKIKSLES 1565 Query: 525 NMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELH----HLSQKVAELEEEKGN 580 + +K NH ++ T N K S ++I +L+++ L K +L+E K + Sbjct: 1566 KINSIKENHSKEI-----TTHNEQKTS-LKQDIAKLSQDHESAQTQLEDKENQLKELKAS 1619 Query: 581 LQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAI--SLLESQKFDLVQELHILQQKYD 638 L+ H + + +++ K++ E +T LK +L +SQK E L+ K Sbjct: 1620 LEKHNTESATSIEEKNNQIKELSETIKSLKTELKTSGDALKQSQK-----EYKTLKTKNS 1674 Query: 639 EVEDK----LADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYG 694 + E K L ++ +++SD ++ K + E+ AL + + + + + L Sbjct: 1675 DTESKLEKQLEELEKVKSDLQTADEKLKGITEREIALKSELETVKNSGLSTTSELAALTK 1734 Query: 695 TIKDLENDKEDIM----NK---LQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKI 747 T+K LE +KE++ NK L++YIQ++ D+++KL+ ++ EL K + SK Sbjct: 1735 TVKSLEKEKEELQFLSGNKSKELEDYIQKHSDISEKLKALT----DELKEKTKQFDDSKK 1790 Query: 748 Q-TQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYL 806 + T+ D +++L E +++ SK+K+ R ++ I + L+ L Sbjct: 1791 KLTELENDLTSTKKEL--ETEKTQTSKFKNLEERKDKEIVKLNKELELLKNDNSGAKKEL 1848 Query: 807 QEK-QKAYSEYTIQEDELVNRLAVLMDHDRV 836 EK K SE I +L ++ +V+ HD + Sbjct: 1849 SEKVSKLESEIEILSKKLEDKKSVMKQHDEL 1879 >UniRef50_A0DBC2 Cluster: Chromosome undetermined scaffold_44, whole genome shotgun sequence; n=1; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_44, whole genome shotgun sequence - Paramecium tetraurelia Length = 2045 Score = 160 bits (388), Expect = 3e-37 Identities = 269/1279 (21%), Positives = 550/1279 (43%), Gaps = 117/1279 (9%) Query: 387 SQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKD 446 +Q+ T NQ+T +IN + LN D + + + + Sbjct: 670 TQIQINTENQET--QINNQVETNTQFTQHELNHQNQDTQITVETGEKRIQTINQQETQE- 726 Query: 447 TLIAQLQLEHQQHMEGPSLIHVGTNT---EDVNEIAKVQEQLKQELNDEIKDVNVKDLIE 503 + Q++ E Q S + T T +++ E A Q+ + NDEIK K LI+ Sbjct: 727 -IQVQIETEDQNTQYVTSQENQNTQTIEQQNIIETADQNTQMSFDENDEIK----KQLIQ 781 Query: 504 KLKSAEE-QITQLNDEIDAANKNMIKVKSNHKL-KLKQMQKTIDNFSKVSDSNK-EIVRL 560 + + + + +Q DE + N+ I + N ++ KLK +++ + + + +R Sbjct: 782 EDQEIQTVECSQDQDESNQKNQAFILEQLNQEIEKLKDQINQQQQAAQMENEKRLDQMRE 841 Query: 561 TEELHHLSQKVAELEEEKGNLQLHL---VDYDSGRMIESDVYKKMIEMENLAETRLKAIS 617 E LH Q ++E ++++ L +L +D G M+ +E+L + + Sbjct: 842 IENLHQQVQFISEQKDQQSQLLNNLLMQIDKQQGEDSSQCNQSNML-IEDLQAQLYEQLV 900 Query: 618 LLESQKFDLVQ-ELHILQQ--KYDEVEDKLADISQLQSD--QVCSEIKSVH--LEEQIDA 670 +E QK D++ + H+LQ+ + ++E K+ + D Q E S++ L++Q + Sbjct: 901 RVEDQKKDIITYQDHLLQKDTQNKQIEQKVELLLSQVEDIMQKFQEQMSINQELKQQNNQ 960 Query: 671 LSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAE 730 + E ++L+ D E L + +L NDK+DI I EN +L K +++ ++ Sbjct: 961 QNQIITEFQEKNQSLQNDIEILQSKLSNLSNDKQDI----DQIISENQELKFKNQQILSQ 1016 Query: 731 KISELLAKINHEEQSKIQTQF------GIDAKIQE-RDLYIENIE-SELSKYKSRICRLE 782 + E K N E+ + ++ KI+E ++L+ E+ E SE ++ +++ Sbjct: 1017 -VEEFENKFNESEKLQSDYEYLEQIFAQSQIKIKELQNLFAESQELSENTQTENKSQMFN 1075 Query: 783 ESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEY--TIQED--ELVNRLAVLMDHDRVVE 838 +S ++ E + L+ +L E+ + E ++QE+ E++ + D+++ +E Sbjct: 1076 KSTSMNEQDGFKLKLDQQELQQEEIEQVQNNDELQKSVQEEQNEIIEQRDNTEDNEKQIE 1135 Query: 839 KQLLEIEHENKELQKKNQILLEENQNLQISLSDMQ------QHYNALVEKANRTDLAESE 892 L N+ KK I + ++ + +S + Q + E+ N D E + Sbjct: 1136 VDLTSSNITNETEIKKVNITNKSDEFIDLSQKQKEGEIENVQFKSETDEQQNFQDQQEQQ 1195 Query: 893 STKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLE--IEFNTQIESAIRDKKVLNEKY 950 S ++ +L++ L TH+ +I QK +EI+ L+ I+ N Q E +R+ +L EK Sbjct: 1196 SEIDNNKITNLQNTLLNSTHQ---MIEQKIEEIQQLQDLIQKNKQSEQELRE--ILQEKE 1250 Query: 951 EKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINE 1010 +N LE QL + K+ + + EEL++ L+ K Q Q+ D+ E Sbjct: 1251 ARN----QNLELQLDDLKSQLSLNQLKEEELSQQINSLL-KQNQDQEHNLSDFQNSKSQE 1305 Query: 1011 INKLNALLK------QKDEEIIALNQKINNAQVSY-------MSMVSDYESKLAQFTTKL 1057 IN LN ++ + E + Q+ Q Y +V E K Q T L Sbjct: 1306 INDLNLQIQNLVEALKNSESQLTKQQQSECLQTGYEEELKQLKDLVQQNEEKNHQHQTAL 1365 Query: 1058 ENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQ-------IKELKETKLTFEMNIPKTE 1110 + + E+Q S +L +S + +L+ + ++ IKEL E ++ I + E Sbjct: 1366 QEAQLELQTTSLELENSFKKISQLESTIENNQEEKNQLENSIKELSEKDKLLQIQIEQYE 1425 Query: 1111 GMIISST--IEPMSDDANNV--DXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNT 1166 + T IE + N + + LK Q+ E +E V + + Sbjct: 1426 KQSQNYTQQIEQLQSTLNQLQNEYQQLTSELNEEQLKNQKIIEINKENEVKVQLIQQDYQ 1485 Query: 1167 ELQECYTKIIQ-----LETLNTELTGHD--VVN-QEQINQLKSKLEQLNTENDNLLSTVA 1218 + + K+ Q ++ LN +L+ + ++N +++I L+ ++++LN ND + Sbjct: 1486 HISQTLVKLEQQSSEEIDGLNEQLSQKEKEILNLKQEIQVLQKQVDELNLNNDEIKRNQE 1545 Query: 1219 ELRSSISSAVDQRGFEIAELWKQHLAQREADFQ-----KTEHELRV-QLSAFESKYEQLL 1272 LR + Q E+ L ++ + +++ +++ E V Q + E +Y Q+ Sbjct: 1546 ILREQ-DGKLKQEKEELQSLLQKEEQENQSNADMIVELESKFEKAVYQRNEMEKEYLQIK 1604 Query: 1273 DSV----QSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYAD---VINQIEILRS 1325 D + ++ Q+ I E+ +L ++++ K+ ++ LQ++ D I QIEI + Sbjct: 1605 DKISHLEKNYIQKNEQYIALYEESNNLNDQVKGKQHQIQILQKQNEDQNAFIKQIEIALT 1664 Query: 1326 EIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXX 1385 EI L NQ + +++ I N+ ++ Q +K+ Sbjct: 1665 EIYSNLSQESIQSLDVNSLDKIKSNILNNINQIRESFKKE-IENLTQQLKQSQKACQEAK 1723 Query: 1386 XXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYE 1445 ++ + + Q+ + + K +E Q ++ + V Q+ + E Sbjct: 1724 QQLGDYQQKLILCGTEYSKKEQQINQELQQTQTKFNEQVEKANQIFNQLQKVEQKKKDLE 1783 Query: 1446 KRIEDLTYEKESELAILRLKMHENANHYETM-QKESEIERVKLIEELNVKITESVSLNKQ 1504 K+++D ++ +L ++ K E N ++ +K+SEI ++ +L+ + + LN+Q Sbjct: 1784 KQVQDSDKIRKDQLEEIKSKQSEIENLKNSINKKQSEINTLQT--QLSSQQQDIQKLNEQ 1841 Query: 1505 VAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQ-KHVSFASD 1563 NK + + + ++ +++ E I TLN I N Q + + K K + + Sbjct: 1842 ----NKVIVNKNCEIQQLTKKIQSYEETIETLNQSIINFQFVNETAQQKFDIKEEEYENK 1897 Query: 1564 TKQGRDEQLDNTMNKELLD 1582 K+ ++ N +NK+L + Sbjct: 1898 IKEYKEN--INQLNKQLAE 1914 Score = 136 bits (328), Expect = 6e-30 Identities = 222/1112 (19%), Positives = 445/1112 (40%), Gaps = 94/1112 (8%) Query: 212 EDTKQQMTKMQENFIAMEAEWKDEKQRL------LKDIESKDVRISSLEEANKLLEAARF 265 ED K+ + Q++ + + + K +Q++ ++DI K S+ + K + Sbjct: 903 EDQKKDIITYQDHLLQKDTQNKQIEQKVELLLSQVEDIMQKFQEQMSINQELKQQNNQQN 962 Query: 266 EISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELT 325 +I E + Q L+ KQ I+ E E++ K ++ + E Sbjct: 963 QIITEFQEKNQSLQNDIEILQSKLSNLSN-DKQDIDQIISENQELKFKNQQILSQVEEFE 1021 Query: 326 KKI----------ELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSG 375 K E LE + Q + KEL+N A S+ + +K S Sbjct: 1022 NKFNESEKLQSDYEYLEQIFAQSQIKIKELQNLFAESQELSENTQTENKSQMFNKSTSMN 1081 Query: 376 RNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXX 435 K+K +L E + Q + + + + + I + D E I E D Sbjct: 1082 EQDGFKLKLDQQELQQEEIEQVQNNDELQKSVQEEQNEIIEQRDNTEDNEKQI-EVDLTS 1140 Query: 436 XXXXXXXXGKDTLIAQLQLEH----QQHMEGP-SLIHVGTNTEDVNEIAKVQEQLKQELN 490 K I E Q+ EG + + T++ QEQ + N Sbjct: 1141 SNITNETEIKKVNITNKSDEFIDLSQKQKEGEIENVQFKSETDEQQNFQDQQEQQSEIDN 1200 Query: 491 DEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKV 550 ++I ++ L + E++I ++ D KN + ++ L++ + N Sbjct: 1201 NKITNLQNTLLNSTHQMIEQKIEEIQQLQDLIQKNKQSEQELREI-LQEKEARNQNLELQ 1259 Query: 551 SDSNKEIVRLTE-ELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLA 609 D K + L + + LSQ++ L ++ + + +L D+ + + ++ ++++NL Sbjct: 1260 LDDLKSQLSLNQLKEEELSQQINSLLKQNQDQEHNLSDFQNSK--SQEINDLNLQIQNLV 1317 Query: 610 ETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSD---QVCSEIKSVHLEE 666 E + S L Q Q+ LQ Y+E +L D+ Q + Q + ++ LE Sbjct: 1318 EALKNSESQLTKQ-----QQSECLQTGYEEELKQLKDLVQQNEEKNHQHQTALQEAQLEL 1372 Query: 667 QIDAL---SASKK--ELALVIENLKLDKEQLYGTIKDL-ENDK------EDIMNKLQNYI 714 Q +L ++ KK +L IEN + +K QL +IK+L E DK E + QNY Sbjct: 1373 QTTSLELENSFKKISQLESTIENNQEEKNQLENSIKELSEKDKLLQIQIEQYEKQSQNYT 1432 Query: 715 QENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKY 774 Q+ L L ++ E +L +++N EEQ K Q I+ +E ++ ++ I+ + Sbjct: 1433 QQIEQLQSTLNQLQNE-YQQLTSELN-EEQLKNQKIIEIN---KENEVKVQLIQQDYQHI 1487 Query: 775 KSRICRLE----ESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVL 830 + +LE E I + ++ E++ L +Q QK E + DE+ +L Sbjct: 1488 SQTLVKLEQQSSEEIDGLNEQLSQKEKEILNLKQEIQVLQKQVDELNLNNDEIKRNQEIL 1547 Query: 831 MDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAE 890 + D +++ E +ELQ Q +ENQ+ + +++ + V + N Sbjct: 1548 REQDG-------KLKQEKEELQSLLQKEEQENQSNADMIVELESKFEKAVYQRN------ 1594 Query: 891 SESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKY 950 E K Q++D S+L++ + + +E +L N Q++ ++L ++ Sbjct: 1595 -EMEKEYLQIKDKISHLEKNYIQKNEQYIALYEESNNL----NDQVKGKQHQIQILQKQN 1649 Query: 951 EKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINE 1010 E ++ Q+E L E +N+ E + +++ +DK E + E Sbjct: 1650 EDQNAFIKQIEIALTEIYSNLSQ-----ESIQSLDVNSLDKIKSNILNNINQIRESFKKE 1704 Query: 1011 INKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQ 1070 I L LKQ + Q++ + Q + ++Y K Q +L+ + + ++Q Sbjct: 1705 IENLTQQLKQSQKACQEAKQQLGDYQQKLILCGTEYSKKEQQINQELQQTQTKF---NEQ 1761 Query: 1071 LLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDX 1130 + + Q +LQ + +++ D K+++++ I K + I S + + N+++ Sbjct: 1762 VEKANQIFNQLQKVEQKKKDLEKQVQDSD-----KIRKDQLEEIKSKQSEIENLKNSINK 1816 Query: 1131 XXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQ----LETLNTELT 1186 L Q+++ IQ+ + + N E+Q+ KI +ETLN + Sbjct: 1817 KQSEINTLQTQLSSQQQD--IQKLNEQNKVIVNKNCEIQQLTKKIQSYEETIETLNQSII 1874 Query: 1187 GHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEI-AELWKQHLAQ 1245 VN+ + K E+ + + +L ++ G ++ + Q + + Sbjct: 1875 NFQFVNETAQQKFDIKEEEYENKIKEYKENINQLNKQLAERQLDEGVQVQIQELSQKIRK 1934 Query: 1246 READFQKTEHELRVQLSAFESKYEQLLDSVQS 1277 +E + +HE L K++ + S Q+ Sbjct: 1935 KEEIIVQLQHEKEQILENCNKKFQMISQSQQN 1966 Score = 128 bits (309), Expect = 1e-27 Identities = 258/1395 (18%), Positives = 564/1395 (40%), Gaps = 82/1395 (5%) Query: 216 QQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLA 275 QQ+ MQ N A KQ +KD+++ + I L + +++ I + Sbjct: 260 QQINSMQNNKQKQSALLNIVKQ--IKDLKTNQIDIEDLRNQFQNIQSL---IETQLINFI 314 Query: 276 QELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLN 335 Q +Q L + ++ S ++ I + E + + K ELL L Sbjct: 315 QNQKQQDNQKIEQQEYEDELTDEDMK-SVQQLIRIYNRKQSESGDKDIIQNKQELLPRLL 373 Query: 336 CQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLN 395 I+ ELE L T S + S S ++ +++ +Q S+E Sbjct: 374 KYIQHLQNELE-VLREQPTWSYQQNHTS-------SEQNQDVITLELQQQLNQTSNELYK 425 Query: 396 QDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLE 455 + +K +I L + I+ L ++K E + + + Sbjct: 426 VQAEFAESKAQIEALNIQIEDLTNQNLEKSAKNDEIQKQLQENQNKGNQDEKAFQNQETQ 485 Query: 456 HQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVN-VKDLIEKLKSAEEQITQ 514 Q +E S I + +D E+ + ++ND+ + N ++++I+ E+Q Q Sbjct: 486 TVQLIEDESQIKQIEDQQDEKELKINSPPQETQVNDDGQQNNLIQEVIKTDNDDEKQFNQ 545 Query: 515 LNDEIDAA------NKNMIKVKSNHKLKLKQMQKTIDNFSK--VSDSNKEIVRLTEELHH 566 + I A ++ N K ++ Q+ +T F++ +S N++ + Sbjct: 546 NDQSIQTAIEQCDQTTQILLETENQKNQISQVVETTTQFTQHEISQENQDTQINVQTDDK 605 Query: 567 LSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDL 626 Q + E ++ Q+ + + + E E ++ + D Sbjct: 606 KIQVITEQGTQETQAQIDTDHQTTQYTAAQEDQNTQTQSEIDDEKQINLNDQQQQTNIDQ 665 Query: 627 VQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLK 686 + +Q + E ++ + + + E+ + + QI + K+ + + + Sbjct: 666 SDQNTQIQINTENQETQINNQVETNTQFTQHELNHQNQDTQITVETGEKRIQTINQQETQ 725 Query: 687 LDKEQLYGTIKDLENDKEDIMNKLQNYIQENM-DLTDKLEKMSAEKISELLAKINHEEQS 745 + Q+ ++ + Q Q+N+ + D+ +MS ++ E+ ++ E+Q Sbjct: 726 EIQVQIETEDQNTQYVTSQENQNTQTIEQQNIIETADQNTQMSFDENDEIKKQLIQEDQE 785 Query: 746 --KIQTQFGIDAKIQERDLYI-ENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQL 802 ++ D Q+ +I E + E+ K K +I + +++ + ++R R+ + L Sbjct: 786 IQTVECSQDQDESNQKNQAFILEQLNQEIEKLKDQINQQQQAAQMENEKRLDQMREIENL 845 Query: 803 GSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEEN 862 +Q SE Q+ +L+N L LM D+ + + N ++ L E+ Sbjct: 846 HQQVQ----FISEQKDQQSQLLNNL--LMQIDKQQGEDSSQCNQSNMLIEDLQAQLYEQL 899 Query: 863 QNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKK 922 ++ D+ + + L++K + E + +Q+ D+ + +Q L Q Sbjct: 900 VRVEDQKKDIITYQDHLLQKDTQNKQIEQKVELLLSQVEDIMQKFQEQMSINQELKQQNN 959 Query: 923 KEIEDLEIEFNTQIESAIRDKKVLNEKYEK---NIEYVTQLEAQLQEYKNNIENLNMNVE 979 ++ + EF + +S D ++L K + + + Q+ ++ QE K + + VE Sbjct: 960 QQ-NQIITEFQEKNQSLQNDIEILQSKLSNLSNDKQDIDQIISENQELKFKNQQILSQVE 1018 Query: 980 EL-NKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKIN-NAQV 1037 E NK N + ++ QS DY +Y+ +I + + ++ + + A +Q+++ N Q Sbjct: 1019 EFENKFN--------ESEKLQS-DY--EYLEQIFAQSQIKIKELQNLFAESQELSENTQT 1067 Query: 1038 SYMSMVSDYESKL-AQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELK 1096 S + + + + Q KL+ ++E+Q+ + ++ Q+N+ELQ V+E+ ++I E + Sbjct: 1068 ENKSQMFNKSTSMNEQDGFKLKLDQQELQQ---EEIEQVQNNDELQKSVQEEQNEIIEQR 1124 Query: 1097 ETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEE-EFIQERS 1155 + E N + E + SS I ++ V+ K +E E E +Q +S Sbjct: 1125 DNT---EDNEKQIEVDLTSSNITNETE-IKKVNITNKSDEFIDLSQKQKEGEIENVQFKS 1180 Query: 1156 VLQEQSAKLNTELQECYTKIIQLETL-NTELTG-HDVVNQ--EQINQLKSKLEQLNTEND 1211 EQ + + Q+ ++ L NT L H ++ Q E+I QL+ L Q N +++ Sbjct: 1181 ETDEQQNFQDQQEQQSEIDNNKITNLQNTLLNSTHQMIEQKIEEIQQLQD-LIQKNKQSE 1239 Query: 1212 NLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQL 1271 L + + + + + ++ ++ +L K L+ + ++ ++ L + + L Sbjct: 1240 QELREILQEKEARNQNLE---LQLDDL-KSQLSLNQLKEEELSQQINSLLKQNQDQEHNL 1295 Query: 1272 LDSVQSSTQEETNKIVTMEQ-VTSLQNKLQD--KEEHLRNLQEKYADVINQIEILRSEIE 1328 D S +QE + + ++ V +L+N K++ LQ Y + + Q++ L + E Sbjct: 1296 SDFQNSKSQEINDLNLQIQNLVEALKNSESQLTKQQQSECLQTGYEEELKQLKDLVQQNE 1355 Query: 1329 DEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXX 1388 ++ +L + Q+ E +I N EE QL+ S Sbjct: 1356 EKNHQHQTALQEAQLELQTTSLELENSFKKISQL-ESTIENNQEEKNQLENSIKELSEKD 1414 Query: 1389 XXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRI 1448 ++ E + T Q+E S + Q +EY ++ N+E + Q+++E K Sbjct: 1415 KLLQIQIEQYEKQSQNYTQQIEQLQSTLNQLQNEYQQLTSELNEE-QLKNQKIIEINK-- 1471 Query: 1449 EDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAEL 1508 E E ++ +++ + ++++S E L E+L+ K E ++L +++ L Sbjct: 1472 -----ENEVKVQLIQQDYQHISQTLVKLEQQSSEEIDGLNEQLSQKEKEILNLKQEIQVL 1526 Query: 1509 NKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGR 1568 K ++E +E++ E + L E LQ++++ + Q + + + Sbjct: 1527 QKQVDELNLNNDEIKRNQEILREQDGKLKQEKEELQSLLQKEEQENQSNADMIVELESKF 1586 Query: 1569 DEQL--DNTMNKELL 1581 ++ + N M KE L Sbjct: 1587 EKAVYQRNEMEKEYL 1601 Score = 128 bits (308), Expect = 2e-27 Identities = 207/1060 (19%), Positives = 438/1060 (41%), Gaps = 98/1060 (9%) Query: 306 EKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKK 365 + +IE+K L ++ + ++ +K + +N +++Q N + +N++ T E + + + Sbjct: 922 QNKQIEQKVELLLSQVEDIMQKFQEQMSINQELKQQNNQ-QNQIIT---EFQEKNQSLQN 977 Query: 366 GSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKE 425 ++ K + S K Q+ SE + +++ + E K D E Sbjct: 978 DIEILQSKL--SNLSNDKQDIDQIISENQELKFKNQQILSQVEEFENKFNESEKLQSDYE 1035 Query: 426 Y---VISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQ 482 Y + ++ L Q E++ M S N +D ++ Q Sbjct: 1036 YLEQIFAQSQIKIKELQNLFAESQELSENTQTENKSQMFNKS---TSMNEQDGFKLKLDQ 1092 Query: 483 EQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQK 542 ++L+QE EI+ V D ++K S +E+ ++ ++ D N ++++ Sbjct: 1093 QELQQE---EIEQVQNNDELQK--SVQEEQNEIIEQRDNTEDN------EKQIEVDLTSS 1141 Query: 543 TIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKM 602 I N +++ N I ++E LSQK E E E N+Q + + + Sbjct: 1142 NITNETEIKKVN--ITNKSDEFIDLSQKQKEGEIE--NVQFKSETDEQQNFQDQQEQQSE 1197 Query: 603 IE---MENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCS-E 658 I+ + NL T L + + QK + +Q+L L QK + E +L +I Q + + + E Sbjct: 1198 IDNNKITNLQNTLLNSTHQMIEQKIEEIQQLQDLIQKNKQSEQELREILQEKEARNQNLE 1257 Query: 659 IKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENM 718 ++ L+ Q+ ++EL+ I +L + + D +N K +N L IQ + Sbjct: 1258 LQLDDLKSQLSLNQLKEEELSQQINSLLKQNQDQEHNLSDFQNSKSQEINDLNLQIQNLV 1317 Query: 719 D-LTDKLEKMSAEKISELLAKINHEE--------QSKIQTQFGIDAKIQERDLYIENIES 769 + L + +++ ++ SE L EE Q + +QE L ++ Sbjct: 1318 EALKNSESQLTKQQQSECLQTGYEEELKQLKDLVQQNEEKNHQHQTALQEAQLELQTTSL 1377 Query: 770 ELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAV 829 EL +I +LE +I ++ + LE +L + Q +Y Q ++ Sbjct: 1378 ELENSFKKISQLESTIENNQEEKNQLENSIKELSEKDKLLQIQIEQYEKQSQNYTQQIEQ 1437 Query: 830 LMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLA 889 L ++ + ++ E E Q KNQ ++E N+ ++ + +QQ Y + + + + Sbjct: 1438 LQSTLNQLQNEYQQLTSELNEEQLKNQKIIEINKENEVKVQLIQQDYQHISQTLVKLEQQ 1497 Query: 890 ESESTK-YQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNE 948 SE QL E + + E Q L +K++++L + N +I+ R++++L E Sbjct: 1498 SSEEIDGLNEQLSQKEKEILNLKQEIQVL----QKQVDELNLN-NDEIK---RNQEILRE 1549 Query: 949 KYEKNIEYVTQLEAQLQ-EYKNNIENLNMNVE-------------ELNKMNLELIDK--H 992 + K + +L++ LQ E + N N +M VE E+ K L++ DK H Sbjct: 1550 QDGKLKQEKEELQSLLQKEEQENQSNADMIVELESKFEKAVYQRNEMEKEYLQIKDKISH 1609 Query: 993 VQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMV----SDYES 1048 ++K Q + E N LN +K K +I L QK N Q +++ + ++ S Sbjct: 1610 LEKNYIQKNEQYIALYEESNNLNDQVKGKQHQIQIL-QKQNEDQNAFIKQIEIALTEIYS 1668 Query: 1049 KLAQFTTK--------------LENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKE 1094 L+Q + + L N+ + + K++ + Q ++ Q +E Q+ + Sbjct: 1669 NLSQESIQSLDVNSLDKIKSNILNNINQIRESFKKEIENLTQQLKQSQKACQEAKQQLGD 1728 Query: 1095 LKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQER 1154 ++ + K E I + + V+ KV+++++ ++++ Sbjct: 1729 YQQKLILCGTEYSKKEQQINQELQQTQTKFNEQVEKANQIFNQLQ---KVEQKKKDLEKQ 1785 Query: 1155 SVLQEQSAKLNTELQECYTKIIQLETLNTELTG-HDVVN--QEQINQLKSKLEQLNTEND 1211 +Q+ +L+E +K ++E L + +N Q Q++ + +++LN +N Sbjct: 1786 --VQDSDKIRKDQLEEIKSKQSEIENLKNSINKKQSEINTLQTQLSSQQQDIQKLNEQNK 1843 Query: 1212 NLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQL 1271 +++ E++ Q E E Q + +FQ + + E +YE Sbjct: 1844 VIVNKNCEIQQLTKKI--QSYEETIETLNQSII----NFQFVNETAQQKFDIKEEEYENK 1897 Query: 1272 LDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQE 1311 + + + + ++ + +Q ++Q+ + +R +E Sbjct: 1898 IKEYKENINQLNKQLAERQLDEGVQVQIQELSQKIRKKEE 1937 Score = 122 bits (293), Expect = 1e-25 Identities = 208/1077 (19%), Positives = 458/1077 (42%), Gaps = 95/1077 (8%) Query: 49 ERQIKFERAQKCLENAALVSKRIKEHRKATAELLGRPFVPGISESLANTLKQKEILMEKI 108 + QIK + Q + +S+ + K+ ++ + + L Q+E+ E+I Sbjct: 1043 QSQIKIKELQNLFAESQELSENTQTENKS--QMFNKSTSMNEQDGFKLKLDQQELQQEEI 1100 Query: 109 KQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNALSVLQVKMKIM 168 +Q + + + + +V S+ I N + +V + Sbjct: 1101 EQVQNNDELQKSVQEEQNEIIEQRDNTEDNEKQIEVDLTSSNIT---NETEIKKVNITNK 1157 Query: 169 ETTILDLQEKINEKD-QIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIA 227 +DL +K E + + ++ K++ + T Q T + N Sbjct: 1158 SDEFIDLSQKQKEGEIENVQFKSETDEQQNFQDQQEQQSEIDNNKITNLQNTLL--NSTH 1215 Query: 228 MEAEWKDEKQRLLKDIESKDVRISS-LEEANKLLEAARFEISLEHSKLAQELEQXXXXXX 286 E K E+ + L+D+ K+ + L E + EA + L+ L +L Sbjct: 1216 QMIEQKIEEIQQLQDLIQKNKQSEQELREILQEKEARNQNLELQLDDLKSQLSLNQLKEE 1275 Query: 287 XXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIE-LLEHLNCQIRQTNKEL 345 L KQ+ + ++ + S EI +L +I+ L+E L Q K+ Sbjct: 1276 ELSQQINSLLKQNQDQE-HNLSDFQNSKSQEI---NDLNLQIQNLVEALKNSESQLTKQQ 1331 Query: 346 ENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKN 405 +++ G E + K+ L+ + +N + +QL +T + + + K Sbjct: 1332 QSECLQTGYEEEL-----KQLKDLVQQNEEKNHQHQTALQEAQLELQTTSLELENSFKK- 1385 Query: 406 EIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSL 465 I++LE I++ ++ E I E KD L+ Q+Q+E + Sbjct: 1386 -ISQLESTIENNQEEKNQLENSIKELSE-----------KDKLL-QIQIEQYEKQSQNYT 1432 Query: 466 IHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKN 525 + +N++ +QL ELN+E + + +IE K E ++ + + ++ Sbjct: 1433 QQIEQLQSTLNQLQNEYQQLTSELNEE--QLKNQKIIEINKENEVKVQLIQQDYQHISQT 1490 Query: 526 MIKVKSNHKLKLKQMQKTIDNFSK-VSDSNKEIVRLTEELHHLSQKVAEL----EEEKGN 580 ++K++ +Q + ID ++ +S KEI+ L +E+ L ++V EL +E K N Sbjct: 1491 LVKLE-------QQSSEEIDGLNEQLSQKEKEILNLKQEIQVLQKQVDELNLNNDEIKRN 1543 Query: 581 LQLHLVDYDSGRMIESDVYKKMIEMENLA-ETRLKAISLLESQKFDLVQELHILQQKYDE 639 ++ L + D E + + +++ E ++ I LES+ V + + ++++Y + Sbjct: 1544 QEI-LREQDGKLKQEKEELQSLLQKEEQENQSNADMIVELESKFEKAVYQRNEMEKEYLQ 1602 Query: 640 VEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDL 699 ++DK IS L+ + + + + L E+ + L+ K I+ L+ E IK + Sbjct: 1603 IKDK---ISHLEKNYIQKNEQYIALYEESNNLNDQVKGKQHQIQILQKQNEDQNAFIKQI 1659 Query: 700 ENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQE 759 E +I + L +++D+ + L+K+ S +L IN +S + + ++++ Sbjct: 1660 EIALTEIYSNLSQESIQSLDV-NSLDKIK----SNILNNINQIRESFKKEIENLTQQLKQ 1714 Query: 760 RDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQ 819 + + +L Y+ ++ ++ YS +K Q+ LQ+ Q ++E + Sbjct: 1715 SQKACQEAKQQLGDYQQKL--------ILCGTEYS--KKEQQINQELQQTQTKFNEQVEK 1764 Query: 820 EDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNAL 879 +++ N+L + VE++ ++E K++Q ++I ++ + ++ S+++ N++ Sbjct: 1765 ANQIFNQL-------QKVEQKKKDLE---KQVQDSDKIRKDQLEEIKSKQSEIENLKNSI 1814 Query: 880 VEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESA 939 +K + + +++ + Q ++ L K I +++ I Q K+I+ E T +S Sbjct: 1815 NKKQSEINTLQTQLSSQQQDIQKLNEQNKVIVNKN-CEIQQLTKKIQSYEETIETLNQSI 1873 Query: 940 IRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELN-----KMNLELIDKHVQ 994 I + V +K + E +++EYK NI LN + E ++ ++ + + ++ Sbjct: 1874 INFQFVNETAQQKFDIKEEEYENKIKEYKENINQLNKQLAERQLDEGVQVQIQELSQKIR 1933 Query: 995 KQQ---TQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDY---ES 1048 K++ Q EQ + NK ++ Q + +I + I A ++Y + +S Sbjct: 1934 KKEEIIVQLQHEKEQILENCNKKFQMISQSQQNLID-KRIIKEALLNYFDNRAPQKIRQS 1992 Query: 1049 KLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMN 1105 L Q L E+E ++ Q+ K + +++Q ++Q+ Q + LK+ L+F +N Sbjct: 1993 ILQQLCCILTMTEQEAAKIGIQI--QKLNQQDIQ---QKQEQQQQSLKDNLLSFLLN 2044 Score = 101 bits (241), Expect = 2e-19 Identities = 231/1219 (18%), Positives = 510/1219 (41%), Gaps = 138/1219 (11%) Query: 473 EDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSN 532 + V E+ K+ E LK+E K D + +EQI +LN E+ + K Sbjct: 192 QKVLELQKIIETLKEEKEYSKKQFQ-GDYNQLEIQFQEQIQRLNQEMVSQRDLFALEKQQ 250 Query: 533 HKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQ-------LHL 585 + + + I++ ++ + +++ L ++E+ + Q L Sbjct: 251 LNRDIDEYIQQINSMQNNKQKQSALLNIVKQIKDLKTNQIDIEDLRNQFQNIQSLIETQL 310 Query: 586 VDYDSGRMIESDVYKKMIEMEN-LAETRLKAISLL---------ESQKFDLVQE------ 629 +++ + + + + E E+ L + +K++ L ES D++Q Sbjct: 311 INFIQNQKQQDNQKIEQQEYEDELTDEDMKSVQQLIRIYNRKQSESGDKDIIQNKQELLP 370 Query: 630 --LHILQQKYDEVED-KLADISQLQSDQVCSE----IKSVHLEEQIDALSASKKELALVI 682 L +Q +E+E + Q + SE + ++ L++Q++ S ++ Sbjct: 371 RLLKYIQHLQNELEVLREQPTWSYQQNHTSSEQNQDVITLELQQQLNQTSNELYKVQAEF 430 Query: 683 ENLKLDKEQLYGTIKDLEN---DKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKI 739 K E L I+DL N +K +++Q +QEN + ++ EK + ++ + I Sbjct: 431 AESKAQIEALNIQIEDLTNQNLEKSAKNDEIQKQLQENQNKGNQDEKAFQNQETQTVQLI 490 Query: 740 NHEEQSKIQTQFGIDAKIQERDLYIEN--IESELSKYKSRICRLEESIAVMEDRRYSLER 797 E Q K I+ + E++L I + E++++ + ++E I D + Sbjct: 491 EDESQIK-----QIEDQQDEKELKINSPPQETQVNDDGQQNNLIQEVIKTDNDDEKQFNQ 545 Query: 798 KADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQ----- 852 + + +++ + ++ ++ + N+++ +++ + EI EN++ Q Sbjct: 546 NDQSIQTAIEQCDQT-TQILLETENQKNQISQVVETTTQFTQH--EISQENQDTQINVQT 602 Query: 853 --KKNQILLE---ENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRD--LES 905 KK Q++ E + QI Y A E N +E + K Q L D ++ Sbjct: 603 DDKKIQVITEQGTQETQAQIDTDHQTTQYTAAQEDQNTQTQSEIDDEK-QINLNDQQQQT 661 Query: 906 NLKRITHEHQTLIVQKKKEIE-DLEIEFNTQ-----IESAIRDKKVLNEKYEKNIEYVTQ 959 N+ + Q I + +E + + ++E NTQ + +D ++ E EK I+ + Q Sbjct: 662 NIDQSDQNTQIQINTENQETQINNQVETNTQFTQHELNHQNQDTQITVETGEKRIQTINQ 721 Query: 960 -----LEAQLQEYKNNIENL----NMNVEELNKMN-LELIDKHVQKQQTQSPDYTEQYIN 1009 ++ Q++ N + + N N + + + N +E D++ Q ++ + +Q I Sbjct: 722 QETQEIQVQIETEDQNTQYVTSQENQNTQTIEQQNIIETADQNTQMSFDENDEIKKQLIQ 781 Query: 1010 EINKLNAL--------LKQKDEEII--ALNQKINNA--QVSYMSMVSDYES-KLAQFTTK 1056 E ++ + QK++ I LNQ+I Q++ + E+ K + Sbjct: 782 EDQEIQTVECSQDQDESNQKNQAFILEQLNQEIEKLKDQINQQQQAAQMENEKRLDQMRE 841 Query: 1057 LENMEEEMQRVSKQL-LDSKQHNEELQILVREQDDQIKELKETKLTFE----------MN 1105 +EN+ +++Q +S+Q S+ N L + ++Q + + ++ + E + Sbjct: 842 IENLHQQVQFISEQKDQQSQLLNNLLMQIDKQQGEDSSQCNQSNMLIEDLQAQLYEQLVR 901 Query: 1106 IPKTEGMIISSTIEPMSDDANN--VDXXXXXXXXXXXXL--KVQEEEEFIQERSVLQEQS 1161 + + II+ + D N ++ + K QE+ QE Q Sbjct: 902 VEDQKKDIITYQDHLLQKDTQNKQIEQKVELLLSQVEDIMQKFQEQMSINQELKQQNNQQ 961 Query: 1162 AKLNTELQECYTKI-IQLETLNTELTGHDVVNQEQ-INQLKSKLEQLNTENDNLLSTVAE 1219 ++ TE QE + +E L ++L+ ++ N +Q I+Q+ S+ ++L +N +LS V E Sbjct: 962 NQIITEFQEKNQSLQNDIEILQSKLS--NLSNDKQDIDQIISENQELKFKNQQILSQVEE 1019 Query: 1220 LRSSISSAVD-QRGFEIAE--LWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQ 1276 + + + Q +E E + + +E E + + + E+K Q+ + Sbjct: 1020 FENKFNESEKLQSDYEYLEQIFAQSQIKIKELQNLFAESQELSENTQTENK-SQMFNKST 1078 Query: 1277 SSTQEETNKIVTMEQVTSLQ--NKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAF 1334 S +++ K+ +Q + ++Q+ +E +++QE+ ++I Q + +E ++++ Sbjct: 1079 SMNEQDGFKLKLDQQELQQEEIEQVQNNDELQKSVQEEQNEIIEQRD--NTEDNEKQIEV 1136 Query: 1335 XXXXXXXXXXXXXXXXDLRTENQSY----KQMQEQSILNI--NEENAQLKKSSXXXXXXX 1388 ++ ++ + ++ +E I N+ E + + Sbjct: 1137 DLTSSNITNETEIKKVNITNKSDEFIDLSQKQKEGEIENVQFKSETDEQQNFQDQQEQQS 1196 Query: 1389 XXXXXRVNDAEAKVLELTHQ-LELKDSEIYQKTHEYTITLTQRNDEFE-NVRQQLVEYEK 1446 ++ + + +L THQ +E K EI Q L Q+N + E +R+ L E E Sbjct: 1197 EIDNNKITNLQNTLLNSTHQMIEQKIEEIQQLQ-----DLIQKNKQSEQELREILQEKEA 1251 Query: 1447 RIEDLTYEKE---SELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNK 1503 R ++L + + S+L++ +LK E + ++ K+++ + L + N K E LN Sbjct: 1252 RNQNLELQLDDLKSQLSLNQLKEEELSQQINSLLKQNQDQEHNLSDFQNSKSQEINDLNL 1311 Query: 1504 QVAELNKALEEEVAKTNEMQTALENQEIEIVT-LNDEITNLQNMVRASSSKIQKHVSFAS 1562 Q+ L +AL K +E Q + Q + T +E+ L+++V+ + K +H + Sbjct: 1312 QIQNLVEAL-----KNSESQLTKQQQSECLQTGYEEELKQLKDLVQQNEEKNHQHQTALQ 1366 Query: 1563 DTK---QGRDEQLDNTMNK 1578 + + Q +L+N+ K Sbjct: 1367 EAQLELQTTSLELENSFKK 1385 Score = 89.0 bits (211), Expect = 9e-16 Identities = 191/954 (20%), Positives = 383/954 (40%), Gaps = 100/954 (10%) Query: 702 DKEDIMNKLQNYIQENMDLTDKLEKMSAE--KISEL----LAKINHEEQSKIQTQFGIDA 755 D+ I N+ Q I N +KL K+SA+ ++S++ L K N + ++K+ +Q D Sbjct: 135 DQLQISNEFQQIITWNQ-FNEKLNKLSADIKQLSQIKYAPLVKENKQLKAKLSSQ-NQDQ 192 Query: 756 KIQERDLYIENI--ESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAY 813 K+ E IE + E E SK + + + I E + + Q + EKQ+ Sbjct: 193 KVLELQKIIETLKEEKEYSKKQFQGDYNQLEIQFQEQIQRLNQEMVSQRDLFALEKQQLN 252 Query: 814 SEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEEN----QNLQISL 869 + DE + ++ M +++ + LL I + K+L K NQI +E+ QN+Q + Sbjct: 253 RDI----DEYIQQINS-MQNNKQKQSALLNIVKQIKDL-KTNQIDIEDLRNQFQNIQSLI 306 Query: 870 S--------DMQQHYNALVEKANRTDLAESESTKYQTQL------RDLESNLKRITHEHQ 915 + +Q N +E+ D E K QL + ES K I Q Sbjct: 307 ETQLINFIQNQKQQDNQKIEQQEYEDELTDEDMKSVQQLIRIYNRKQSESGDKDIIQNKQ 366 Query: 916 TLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVT---------------QL 960 L+ + K I+ L+ E E + + E+N + +T ++ Sbjct: 367 ELLPRLLKYIQHLQNELEVLREQPTWSYQQNHTSSEQNQDVITLELQQQLNQTSNELYKV 426 Query: 961 EAQLQEYKNNIENLNMNVEELNKMNLEL------IDKHVQKQQTQ----------SPDYT 1004 +A+ E K IE LN+ +E+L NLE I K +Q+ Q + T Sbjct: 427 QAEFAESKAQIEALNIQIEDLTNQNLEKSAKNDEIQKQLQENQNKGNQDEKAFQNQETQT 486 Query: 1005 EQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEM 1064 Q I + +++ + Q+DE+ + +N QV+ ++ L Q K +N +E+ Sbjct: 487 VQLIEDESQIKQIEDQQDEKELKINSPPQETQVN----DDGQQNNLIQEVIKTDNDDEKQ 542 Query: 1065 QRVSKQLLDS--KQHNEELQILV--REQDDQIKELKETKLTF---EMNIPKTEGMIISST 1117 + Q + + +Q ++ QIL+ Q +QI ++ ET F E++ + I T Sbjct: 543 FNQNDQSIQTAIEQCDQTTQILLETENQKNQISQVVETTTQFTQHEISQENQDTQINVQT 602 Query: 1118 ----IEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYT 1173 I+ +++ +E++ Q +S + ++ ++N Q+ T Sbjct: 603 DDKKIQVITEQGTQETQAQIDTDHQTTQYTAAQEDQNTQTQSEIDDEK-QINLNDQQQQT 661 Query: 1174 KIIQLE-----TLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAV 1228 I Q + +NTE + NQ + N ++ +LN +N + TV I + Sbjct: 662 NIDQSDQNTQIQINTENQETQINNQVETNTQFTQ-HELNHQNQDTQITVETGEKRIQTIN 720 Query: 1229 DQRGFEI-AELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIV 1287 Q EI ++ + + Q+ ++ ++ +Q E +++ Sbjct: 721 QQETQEIQVQIETEDQNTQYVTSQENQNTQTIEQQNIIETADQNTQMSFDENDEIKKQLI 780 Query: 1288 TMEQVTSLQNKLQDKEEHLRNLQEKYADVINQ-IEILRSEIEDEKVAFXXXXXXXXXXXX 1346 +Q QD++E + Q + +NQ IE L+ +I ++ A Sbjct: 781 QEDQEIQTVECSQDQDESNQKNQAFILEQLNQEIEKLKDQINQQQQA-AQMENEKRLDQM 839 Query: 1347 XXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELT 1406 +L + Q + ++Q +N Q+ K + D +A++ E Sbjct: 840 REIENLHQQVQFISEQKDQQSQLLNNLLMQIDKQQGEDSSQCNQSNMLIEDLQAQLYEQL 899 Query: 1407 HQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAI-LRLK 1465 ++E + +I Y L Q++ + + + Q++ ++ED+ + + +++I LK Sbjct: 900 VRVEDQKKDII----TYQDHLLQKDTQNKQIEQKVELLLSQVEDIMQKFQEQMSINQELK 955 Query: 1466 MHENANHY---ETMQKESEIER-VKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNE 1521 N + E +K ++ +++++ ++ Q+ N+ L+ + + Sbjct: 956 QQNNQQNQIITEFQEKNQSLQNDIEILQSKLSNLSNDKQDIDQIISENQELKFKNQQILS 1015 Query: 1522 MQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVS-FASDTKQGRDEQLDN 1574 EN+ E L + L+ + S KI++ + FA + + Q +N Sbjct: 1016 QVEEFENKFNESEKLQSDYEYLEQIFAQSQIKIKELQNLFAESQELSENTQTEN 1069 Score = 58.8 bits (136), Expect = 1e-06 Identities = 102/546 (18%), Positives = 222/546 (40%), Gaps = 43/546 (7%) Query: 1056 KLENMEEEMQRVSKQLLDSKQHN-----EELQILVREQDD-QIKELKETKLTFEMNIPKT 1109 K++N ++ V+ LL KQ + E+ Q ++Q D + EL + ++T EM I + Sbjct: 6 KIKNAAGTVKNVTSNLLQEKQTDSDKKQEQTQTQTQKQQDVNLLELDD-QITQEMTIAEL 64 Query: 1110 EGMIISST---IEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNT 1166 + ++ + N + ++ ++ Q L + + + Sbjct: 65 IQKFQQNDCVCLQQQFESWKNQENQYQLLKSKILGIRADFNQQLEQYSQDLWDGAQIVER 124 Query: 1167 ELQECYTKIIQLETLNTELTGHDVVNQ--EQINQLKSKLEQLNT-ENDNLLSTVAELRSS 1223 + E K++ ++ E NQ E++N+L + ++QL+ + L+ +L++ Sbjct: 125 QKIEFILKVLDQLQISNEFQQIITWNQFNEKLNKLSADIKQLSQIKYAPLVKENKQLKAK 184 Query: 1224 ISSA-VDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEE 1282 +SS DQ+ E+ ++ + + E ++ K + F+ Y QL Q Q Sbjct: 185 LSSQNQDQKVLELQKIIET--LKEEKEYSKKQ---------FQGDYNQLEIQFQEQIQRL 233 Query: 1283 TNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXX 1342 ++V+ + +L+ K++ R++ E Y IN ++ ++ + + Sbjct: 234 NQEMVSQRDLFALE-----KQQLNRDIDE-YIQQINSMQ--NNKQKQSALLNIVKQIKDL 285 Query: 1343 XXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKV 1402 DLR + Q+ + + E ++N + Q + ++ Sbjct: 286 KTNQIDIEDLRNQFQNIQSLIETQLINFIQNQKQQDNQKIEQQEYEDELTDEDMKSVQQL 345 Query: 1403 LELTH--QLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVE---YEKRIEDLTYEKES 1457 + + + Q E D +I Q E L + +N + L E + + + E+ Sbjct: 346 IRIYNRKQSESGDKDIIQNKQELLPRLLKYIQHLQNELEVLREQPTWSYQQNHTSSEQNQ 405 Query: 1458 ELAILRLKMHENANHYETMQKESEIERVKL-IEELNVKITESVSLNKQVA----ELNKAL 1512 ++ L L+ N E + ++E K IE LN++I + + N + + E+ K L Sbjct: 406 DVITLELQQQLNQTSNELYKVQAEFAESKAQIEALNIQIEDLTNQNLEKSAKNDEIQKQL 465 Query: 1513 EEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQL 1572 +E K N+ + A +NQE + V L ++ + ++ + K K S +T+ D Q Sbjct: 466 QENQNKGNQDEKAFQNQETQTVQLIEDESQIKQIEDQQDEKELKINSPPQETQVNDDGQQ 525 Query: 1573 DNTMNK 1578 +N + + Sbjct: 526 NNLIQE 531 >UniRef50_A0DWU7 Cluster: Chromosome undetermined scaffold_67, whole genome shotgun sequence; n=3; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_67, whole genome shotgun sequence - Paramecium tetraurelia Length = 1979 Score = 159 bits (387), Expect = 4e-37 Identities = 287/1418 (20%), Positives = 612/1418 (43%), Gaps = 160/1418 (11%) Query: 217 QMTKMQENFIAMEAEWKDEKQRLLKD---IESKDVRISSLEEANKLLEAARFEISLEHSK 273 Q+++ Q+ E+E + KQ++ + I+ ++ LE NKLL+ ++ +E K Sbjct: 342 QLSQFQDLMAEKESEISNLKQQIDDEHELIQEYQKKVKQLENENKLLKLQLSKM-VESEK 400 Query: 274 LAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIAN--MTELTKKIELL 331 Q+ + +S+ + + + K L N + +L ++I L Sbjct: 401 QLQKQKSEANSEYQHYKDDSSQKLKSLSQEIVDLKQKQNKLGLRDCNQEVEQLNQQISKL 460 Query: 332 EHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRN-----TASKMKSPW 386 + + + N + + K M ++ + ++ S R N + K + Sbjct: 461 KSEKEEKERENGQNQIKFQEMKSKYNDLKQSYQELSDQYQRDQQMNKQIVQSLQTQKEDF 520 Query: 387 SQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKD 446 +SE + +++ E+ + +I+ L DL ++ +++T Sbjct: 521 ENRNSEQQSLFHLDLVSQQELETQQQLIKQLENDLHQAQFAYKQQETKLLDYEDEINNLK 580 Query: 447 TLIAQLQLEHQQHMEGPSLIHVGTNT-EDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKL 505 T I +L+ EH + + H+ NT + ++I + E + LND + + + Sbjct: 581 TQIMRLEEEHTEQL------HILDNTIQSKDQIIQQYESNSRILNDTPEQL-------RS 627 Query: 506 KSAEEQITQ--LNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFS-KVSDSNKEIVRLTE 562 KS E+ Q L +ID+ NK++ SN + +++ + K + + ++++ +K + + T+ Sbjct: 628 KSVEQTTIQGHLKSQIDSLNKSL----SNFEQQIRDLTKVNNEYQDQINNKDKILKQKTQ 683 Query: 563 ELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQ 622 E+ L Q++ +L+ +Q+ + ++ ++ L +T K L + Sbjct: 684 EVIQLQQQLKDLQGLNQKIQVQ----------DRAIHHHEKQVSTLNQTIQKLQESLNFK 733 Query: 623 KFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVI 682 L+ + H ++ ++ +D + Q Q Q S+ E+Q ++EL + Sbjct: 734 DQILLGKQHEIEMLLNQKKDHI----QQQKQQ------SLLFEQQHQKAKFEQQELHNKV 783 Query: 683 ENLKLDKEQLYGTIKDLE--NDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKIN 740 + L+ EQ+ KD+ N +E+I LQN IQ+ K ++ S ++ +L KI Sbjct: 784 KQLE---EQIIAKQKDVITINVQEEI---LQNQIQQLEQQMRKHQQDSEDEKKQLNDKIL 837 Query: 741 HEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKAD 800 Q +++ I + E+ + ++N ++++S+ +S + ++ I +E R L+++ Sbjct: 838 RLNQ-ELEEAEKIQISLNEKQVSLDNAQNKVSELESELISSQDQIQQLESRILELQQEIK 896 Query: 801 -QLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILL 859 + ++L++ Q+ E Q E N V M+ D + +K + +E E ++LQ Q L Sbjct: 897 KERSNFLKDNQQKIEELNSQHQE--NEELVQMNQD-LTQKNMQLLE-EIEQLQS-GQSKL 951 Query: 860 EENQNLQISLSDMQQHYNALVEKANRTDLAESES-----TKYQTQLRDLESNLKRITHEH 914 + N N +I +++ N + K ++ + E S + Q + ++ L + E Sbjct: 952 QFNLNQEIQNLRAKENQNKEIIKKHQLQILELNSQISSFNQQQELAKQDKAKLSEMLKEQ 1011 Query: 915 QTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENL 974 I + K++E ++ + QIE + E K E + Q QE + + + Sbjct: 1012 LNTITELNKKLEIENLQNDQQIEE--NKTQFSTELVVKETELCRNVMTQSQETQKLLIQI 1069 Query: 975 NMNVEELNKMNLELIDKHVQKQQTQSPDYTEQY--INEINKLNALLKQKDEEIIALNQKI 1032 +E+L K L +++Q+ Q D ++Y I E +K L++ + E++ +L Q Sbjct: 1070 GTLIEQLEKSKLT-----IKEQEKQLFDQEQKYLIIREESKNQQLIQNQFEKLNSLTQTQ 1124 Query: 1033 NNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDS-KQHNEELQILVREQDDQ 1091 N + + +++ KL E +E+E R S+ L+D+ Q +IL E Q Sbjct: 1125 NLTISNLQNELNEKNLKLQTQVLHAETLEQEF-RNSQVLVDNLNQQLNNFKILNEEYKQQ 1183 Query: 1092 IKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFI 1151 I+ + T + I E I + L QE+E Sbjct: 1184 IQSFTQKFQTNQQQIQNLENKI---------KELEQTRLIQESKINETTLLLKQEQENCT 1234 Query: 1152 QERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTEND 1211 + R+ L E+S +LN ++ E I Q++ N+ QL S+L++ + Sbjct: 1235 KLRNDLTEKSNQLNLQVIE----ITQIQNDNSHF-----------KQLNSELQKNLEARE 1279 Query: 1212 NLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYE-Q 1270 +++ ++ + + + Q+ E+ E + L Q + + +K ++L +QL + E Q Sbjct: 1280 IIIANNIDITNDLDQTIKQKNEELKEKQNKILGQTK-EIEKINNKL-LQLQQQNAMLENQ 1337 Query: 1271 LLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQ-EKYADVINQIEILRSEIED 1329 + + +Q + Q + ++V SLQ+ + E++ + LQ + D N ++ + IE Sbjct: 1338 IQERIQINQQIQ-------QEVNSLQHSNHELEQNNKKLQLQIIQDAQNYNQLNQRNIEL 1390 Query: 1330 EKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXX 1389 ++ DL+ N+ + Q Q I N NE + + Sbjct: 1391 QE---------RNNTLNNEILDLKKNNKELVENQVQ-ITNKNEADQAQNR-------LIG 1433 Query: 1390 XXXXRVNDAEAKVLELTHQLELKDSEI---YQKTHEYTITLTQRNDEFENVRQQLVEYEK 1446 ++N+ E K+++L + L++KD +I Q+ L Q+N++ +L+ +K Sbjct: 1434 SLQEQINNLEQKIIQLENDLKIKDDQITNSIQENQAQEQKLLQQNNQLSQDHGELMALQK 1493 Query: 1447 RIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVA 1506 D ++ ++L +L+ + + +Q E + E ++ +++N + L++Q A Sbjct: 1494 VDYDKIKQQNNQL---QLQTNSQQQDIQRLQLELQQE-IESKQQIN---NSKIELDQQQA 1546 Query: 1507 ELNKALEEEVAKTNEMQTALENQE----IEIVTLNDEITNLQNMVRASSSKI-------- 1554 LN+ L ++ +T ++ L++QE E LN +I NL + + ++ Sbjct: 1547 LLNQKLSQKEQQTQQLDQQLKDQEDLLQKEQNKLNSQIENLNSQISVLRKQLDQLQEIIT 1606 Query: 1555 QKHVSFASDTKQGRDEQ-LDNTMNKELLDAVPRAELDL 1591 QK V A +K+ + Q L N+E+L +++LDL Sbjct: 1607 QKEVELADYSKRESEAQKLFEQKNEEILQL--KSQLDL 1642 Score = 119 bits (287), Expect = 6e-25 Identities = 241/1214 (19%), Positives = 511/1214 (42%), Gaps = 112/1214 (9%) Query: 140 QLGDVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXX 199 QL D+ L+ I+ +D A+ + ++ + TI LQE +N KDQI+ K Sbjct: 691 QLKDLQGLNQKIQVQDRAIHHHEKQVSTLNQTIQKLQESLNFKDQILLGKQ--------- 741 Query: 200 XXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKL 259 +D QQ + F + K E+Q L ++ LEE Sbjct: 742 --HEIEMLLNQKKDHIQQQKQQSLLFEQQHQKAKFEQQELHN-------KVKQLEEQIIA 792 Query: 260 LEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIA 319 + I+++ L +++Q KQ + E+EE ++I+ Sbjct: 793 KQKDVITINVQEEILQNQIQQLEQQMRKHQQDSEDEKKQLNDKILRLNQELEEAEKIQIS 852 Query: 320 NMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTA 379 L +K L++ ++ ELE++L + + + + S + I +K N Sbjct: 853 ----LNEKQVSLDNAQNKV----SELESELISSQDQIQQLESRILELQQEI-KKERSNFL 903 Query: 380 SKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXX 439 + +L+S+ +Q+ ++ + N+ L L +++ + S+ Sbjct: 904 KDNQQKIEELNSQ--HQENEELVQMNQ--DLTQKNMQLLEEIEQLQSGQSKLQFNLNQEI 959 Query: 440 XXXXGKDTLIAQLQLEHQ-QHMEGPSLIHVGTNTEDV--NEIAKVQEQLKQELNDEIKDV 496 K+ ++ +HQ Q +E S I +++ + AK+ E LK++LN I ++ Sbjct: 960 QNLRAKENQNKEIIKKHQLQILELNSQISSFNQQQELAKQDKAKLSEMLKEQLN-TITEL 1018 Query: 497 NVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKE 556 N K IE L+ ND+ NK +L +K+ + + ++ ++ K Sbjct: 1019 NKKLEIENLQ---------NDQQIEENKTQFST----ELVVKETELCRNVMTQSQETQKL 1065 Query: 557 IVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAI 616 ++++ + L + ++E+ + L D + +I + K ++N E K Sbjct: 1066 LIQIGTLIEQLEKSKLTIKEQ----EKQLFDQEQKYLIIREESKNQQLIQNQFE---KLN 1118 Query: 617 SLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKK 676 SL ++Q + + L +K +++ ++ L+ + S++ +L +Q++ + Sbjct: 1119 SLTQTQNLTISNLQNELNEKNLKLQTQVLHAETLEQEFRNSQVLVDNLNQQLNNFKILNE 1178 Query: 677 ELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQEN-MDLTDKLEKMSAEKISEL 735 E I++ + I++LEN +++ + IQE+ ++ T L K E ++L Sbjct: 1179 EYKQQIQSFTQKFQTNQQQIQNLENKIKEL--EQTRLIQESKINETTLLLKQEQENCTKL 1236 Query: 736 LAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSK-YKSRICRLEESIAVMEDRRYS 794 + E+ +++ Q +IQ + + + + SEL K ++R + +I + D + Sbjct: 1237 RNDLT-EKSNQLNLQVIEITQIQNDNSHFKQLNSELQKNLEAREIIIANNIDITNDLDQT 1295 Query: 795 LERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLE-------IEHE 847 +++K ++ L+EKQ T + +++ N+L L + ++E Q+ E I+ E Sbjct: 1296 IKQKNEE----LKEKQNKILGQTKEIEKINNKLLQLQQQNAMLENQIQERIQINQQIQQE 1351 Query: 848 NKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNL 907 LQ N L + N+ LQ+ + Q+YN L ++ +L E +T ++ DL+ N Sbjct: 1352 VNSLQHSNHELEQNNKKLQLQIIQDAQNYNQLNQR--NIELQERNNT-LNNEILDLKKNN 1408 Query: 908 KRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEY 967 K + E+Q I K E + + N I S ++ +N +K I+ L+ + + Sbjct: 1409 KELV-ENQVQIT-NKNEADQAQ---NRLIGSL---QEQINNLEQKIIQLENDLKIKDDQI 1460 Query: 968 KNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEI-- 1025 N+I+ ++L + N +L H + Q DY ++ + N+L + ++I Sbjct: 1461 TNSIQENQAQEQKLLQQNNQLSQDHGELMALQKVDY-DKIKQQNNQLQLQTNSQQQDIQR 1519 Query: 1026 --IALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQI 1083 + L Q+I + Q S + + + + A KL E++ Q++ +QL K + LQ Sbjct: 1520 LQLELQQEIESKQQINNSKI-ELDQQQALLNQKLSQKEQQTQQLDQQL---KDQEDLLQK 1575 Query: 1084 LVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLK 1143 + + QI+ L + + + +I +E + L+ Sbjct: 1576 EQNKLNSQIENLNSQISVLRKQLDQLQEIITQKEVELADYSKRESEAQKLFEQKNEEILQ 1635 Query: 1144 VQEEEEFIQERS-VLQEQSAKLNTELQECYTKIIQLE-TLNTELTGHDVVNQEQINQLKS 1201 ++ + + IQ+ + +Q +++ + + ++I +L+ + + T D + Q NQ + Sbjct: 1636 LKSQLDLIQQNTKEIQNPQKEIDALIAKKDSEIKELQNVIQAKSTQIDKI-QADSNQNQF 1694 Query: 1202 KLEQLNT--ENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRV 1259 L+++ DN+L + + +S +R F + + + + LR Sbjct: 1695 LLQEIKALFNQDNILDYLRQFKSQHEKQC-ERKFTYYQCLQSLM----------DELLRN 1743 Query: 1260 QLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQ 1319 Q +AF Y Q + V+ S QE+ N + + + ++ KL K +EK D+ Sbjct: 1744 QQAAF---YAQ--NYVKLSQQEQNNLLAYQKDIQLMKAKLPVKTALSNIKEEKNEDISFS 1798 Query: 1320 IEILRSEIEDEKVA 1333 ++EI + V+ Sbjct: 1799 SNGQQAEINENDVS 1812 Score = 104 bits (249), Expect = 2e-20 Identities = 212/1122 (18%), Positives = 462/1122 (41%), Gaps = 94/1122 (8%) Query: 514 QLNDEIDAANKNMIKVK---SNHKLKLKQMQKTIDNFSKVSDSNKEIVR----LTE---E 563 Q+ +I A N+++ + N + K ++K + E +R LTE E Sbjct: 76 QIEKKISALKSNLLQSRMSSDNFQFATKPLEKLLKRVDDTGTYKTEQIRADDLLTEILQE 135 Query: 564 LHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQK 623 L +S L+ ++ + +L ++ R I + + + +T +I L++ Sbjct: 136 LSFISINAKLLQNQRSSQKLQMLVLKDIREIVAGWNTMQHIINQICQTAQISIYQLQNTN 195 Query: 624 FDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQID-----ALSASKKEL 678 + + L + Y VE Q +Q+ S I + D ++ ++ Sbjct: 196 ISQLFKRDELNKLYSLVEKHQNSYPQ-SFEQLYSIIANSFQSRDQDHNKLIEINTQLRQQ 254 Query: 679 ALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKM--SAEKISELL 736 + ++L + L+ + LE + NK Q N +++L+ + SE Sbjct: 255 EIQNKDLNTKNKNLFAVVTKLEAKVNKLQNKKQQLELSNKQFSNQLQSSYRPQDTYSEN- 313 Query: 737 AKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLE 796 K H+ +++Q +D+K ++ L ++++LS+++ + E I+ +L+ Sbjct: 314 DKFKHKNPL-VESQSSLDSKNTQQKL----LDNQLSQFQDLMAEKESEIS-------NLK 361 Query: 797 RKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQ 856 ++ D +QE QK + + L +L+ +++ ++ ++KQ E N E Q Sbjct: 362 QQIDDEHELIQEYQKKVKQLENENKLLKLQLSKMVESEKQLQKQKSE---ANSEYQHYKD 418 Query: 857 ILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQT 916 + +Q L+ SLS Q L +K N+ L + + QL S LK E + Sbjct: 419 ---DSSQKLK-SLS---QEIVDLKQKQNKLGL--RDCNQEVEQLNQQISKLKSEKEEKER 469 Query: 917 LIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNM 976 Q + + ++++ ++N +S + L+++Y+++ + Q+ LQ K + E N Sbjct: 470 ENGQNQIKFQEMKSKYNDLKQS----YQELSDQYQRDQQMNKQIVQSLQTQKEDFE--NR 523 Query: 977 NVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQ 1036 N E+ + +L+L+ + Q+ +TQ +Q N++++ KQ++ +++ +INN + Sbjct: 524 NSEQQSLFHLDLVSQ--QELETQQ-QLIKQLENDLHQAQFAYKQQETKLLDYEDEINNLK 580 Query: 1037 VSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELK 1096 M + ++ +L +++ ++ +Q+ E+L+ EQ LK Sbjct: 581 TQIMRLEEEHTEQLHILDNTIQSKDQIIQQYESNSRILNDTPEQLRSKSVEQTTIQGHLK 640 Query: 1097 ETKLTFEMNIPKTEGMI--ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQER 1154 + ++ E I ++ D NN D K QE + Q+ Sbjct: 641 SQIDSLNKSLSNFEQQIRDLTKVNNEYQDQINNKDKILKQ--------KTQEVIQLQQQL 692 Query: 1155 SVLQEQSAKLNTELQECYTKIIQLETLNTELTG-HDVVN-QEQINQLKS-KLEQLNTEND 1211 LQ + K+ + + + Q+ TLN + + +N ++QI K ++E L + Sbjct: 693 KDLQGLNQKIQVQDRAIHHHEKQVSTLNQTIQKLQESLNFKDQILLGKQHEIEMLLNQKK 752 Query: 1212 NLLSTVAELRSSISSAVDQRGFEIAELWK--QHLAQREADFQKTEHELRVQLSAFESKYE 1269 + + + + FE EL + L ++ QK + VQ +++ + Sbjct: 753 DHIQQQKQQSLLFEQQHQKAKFEQQELHNKVKQLEEQIIAKQKDVITINVQEEILQNQIQ 812 Query: 1270 QLLDSVQSSTQE-ETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIE 1328 QL ++ Q+ E K +++ L +L++ E+ +L EK + N + SE+E Sbjct: 813 QLEQQMRKHQQDSEDEKKQLNDKILRLNQELEEAEKIQISLNEKQVSLDNAQNKV-SELE 871 Query: 1329 DEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNIN---EENAQLKKSSXXXX 1385 E ++ +++ E ++ + +Q I +N +EN +L + + Sbjct: 872 SELISSQDQIQQLESRILELQQEIKKERSNFLKDNQQKIEELNSQHQENEELVQMNQDLT 931 Query: 1386 XXXXXXXXRVNDAEAKVLELTHQL----------ELKDSEIYQKTHEYTITLTQRNDEFE 1435 + ++ +L L E ++ EI +K + L + F Sbjct: 932 QKNMQLLEEIEQLQSGQSKLQFNLNQEIQNLRAKENQNKEIIKKHQLQILELNSQISSF- 990 Query: 1436 NVRQQLVEYEK-RIEDLTYEKESELAILRLKMH-ENANHYETMQK-------ESEIERVK 1486 N +Q+L + +K ++ ++ E+ + + L K+ EN + + +++ E ++ + Sbjct: 991 NQQQELAKQDKAKLSEMLKEQLNTITELNKKLEIENLQNDQQIEENKTQFSTELVVKETE 1050 Query: 1487 LIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNM 1546 L + + E+ L Q+ L + LE+ E + L +QE + + + +E N Q + Sbjct: 1051 LCRNVMTQSQETQKLLIQIGTLIEQLEKSKLTIKEQEKQLFDQEQKYLIIREESKN-QQL 1109 Query: 1547 VRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAE 1588 ++ K+ + T +L N N +L V AE Sbjct: 1110 IQNQFEKLNSLTQTQNLTISNLQNEL-NEKNLKLQTQVLHAE 1150 Score = 98.7 bits (235), Expect = 1e-18 Identities = 165/859 (19%), Positives = 356/859 (41%), Gaps = 69/859 (8%) Query: 765 ENIESELSKYKSRICRLEESIAVMEDRRYSLER---KADQLGSYLQEKQKAYSEYT--IQ 819 + IE ++S KS + + S + LE+ + D G+Y E+ +A T +Q Sbjct: 75 QQIEKKISALKSNLLQSRMSSDNFQFATKPLEKLLKRVDDTGTYKTEQIRADDLLTEILQ 134 Query: 820 EDELVNRLAVLMDHDRVVEKQLLEIEHENKEL----QKKNQILLEENQNLQISLSDMQQH 875 E ++ A L+ + R +K + + + +E+ I+ + Q QIS+ +Q Sbjct: 135 ELSFISINAKLLQNQRSSQKLQMLVLKDIREIVAGWNTMQHIINQICQTAQISIYQLQNT 194 Query: 876 YNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQ 935 + + K + + S K+Q L I Q + + + IE NTQ Sbjct: 195 NISQLFKRDELNKLYSLVEKHQNSYPQSFEQLYSIIANS----FQSRDQDHNKLIEINTQ 250 Query: 936 IESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQK 995 + K LN K + VT+LEA++ N ++N +E NK + + Sbjct: 251 LRQQEIQNKDLNTKNKNLFAVVTKLEAKV----NKLQNKKQQLELSNKQFSNQLQSSYRP 306 Query: 996 QQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVS-YMSMVSDYESKLAQFT 1054 Q T S + ++ N + + + L K+ + QK+ + Q+S + ++++ ES+++ Sbjct: 307 QDTYSENDKFKHKNPLVESQSSLDSKNTQ-----QKLLDNQLSQFQDLMAEKESEISNLK 361 Query: 1055 TKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMII 1114 ++++ E +Q K++ + N+ L++ + + + K+L++ K + Sbjct: 362 QQIDDEHELIQEYQKKVKQLENENKLLKLQLSKMVESEKQLQKQKSEANSEYQHYKDDS- 420 Query: 1115 SSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTK 1174 S ++ +S + VD QE E+ Q+ S L+ + + E + K Sbjct: 421 SQKLKSLSQEI--VDLKQKQNKLGLRDCN-QEVEQLNQQISKLKSEKEEKERENGQNQIK 477 Query: 1175 IIQLETLNTEL--TGHDVVNQEQINQLKSK--LEQLNTENDNLLSTVAELRSSIS-SAVD 1229 ++++ +L + ++ +Q Q +Q +K ++ L T+ ++ + +E +S V Sbjct: 478 FQEMKSKYNDLKQSYQELSDQYQRDQQMNKQIVQSLQTQKEDFENRNSEQQSLFHLDLVS 537 Query: 1230 QRGFEIAE-LWKQ-----HLAQ--------READFQKTEHELRVQLSAFESKYEQLLDSV 1275 Q+ E + L KQ H AQ + D++ + L+ Q+ E ++ + L + Sbjct: 538 QQELETQQQLIKQLENDLHQAQFAYKQQETKLLDYEDEINNLKTQIMRLEEEHTEQLHIL 597 Query: 1276 QSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFX 1335 ++ Q + I +Q S L D E LR+ + + ++ + F Sbjct: 598 DNTIQSKDQII---QQYESNSRILNDTPEQLRSKSVEQTTIQGHLKSQIDSLNKSLSNFE 654 Query: 1336 XXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLK---KSSXXXXXXXXXXX 1392 + +++ KQ + Q ++ + ++ L+ + Sbjct: 655 QQIRDLTKVNNEYQDQINNKDKILKQ-KTQEVIQLQQQLKDLQGLNQKIQVQDRAIHHHE 713 Query: 1393 XRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLT 1452 +V+ + +L L KD + K HE + L Q+ D + +QQ + +E++ + Sbjct: 714 KQVSTLNQTIQKLQESLNFKDQILLGKQHEIEMLLNQKKDHIQQQKQQSLLFEQQHQKAK 773 Query: 1453 YEKE---SELAILRLKMHENANHYETMQKESEI--ERVKLIEELNVK-----ITESVSLN 1502 +E++ +++ L ++ T+ + EI +++ +E+ K E LN Sbjct: 774 FEQQELHNKVKQLEEQIIAKQKDVITINVQEEILQNQIQQLEQQMRKHQQDSEDEKKQLN 833 Query: 1503 KQVAELNKALEEE---VAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVS 1559 ++ LN+ LEE NE Q +L+N + ++ L E+ + Q+ ++ S+I + Sbjct: 834 DKILRLNQELEEAEKIQISLNEKQVSLDNAQNKVSELESELISSQDQIQQLESRI---LE 890 Query: 1560 FASDTKQGRDEQLDNTMNK 1578 + K+ R L + K Sbjct: 891 LQQEIKKERSNFLKDNQQK 909 Score = 44.0 bits (99), Expect = 0.035 Identities = 61/342 (17%), Positives = 142/342 (41%), Gaps = 19/342 (5%) Query: 1263 AFESKYEQLLDSVQSSTQEETNKIVTMEQVTSL-QNKLQDKEEHLRNLQEKYADVINQIE 1321 +FE Y + +S QS Q+ NK++ + T L Q ++Q+K+ + +N + +A V+ ++E Sbjct: 222 SFEQLYSIIANSFQSRDQDH-NKLIEIN--TQLRQQEIQNKDLNTKN-KNLFA-VVTKLE 276 Query: 1322 ILRSEIEDEK--VAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQE--QSILNINEENAQL 1377 ++++++K + D +EN +K +S +++ +N Q Sbjct: 277 AKVNKLQNKKQQLELSNKQFSNQLQSSYRPQDTYSENDKFKHKNPLVESQSSLDSKNTQQ 336 Query: 1378 KKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENV 1437 K + E+++ L Q++ + E+ Q+ + L N + Sbjct: 337 KLLDNQLSQFQDLMAEK----ESEISNLKQQID-DEHELIQEYQKKVKQLENENKLLKLQ 391 Query: 1438 RQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKL-IEELNVKIT 1496 ++VE EK+++ E SE + + + + ++ KL + + N ++ Sbjct: 392 LSKMVESEKQLQKQKSEANSEYQHYKDDSSQKLKSLSQEIVDLKQKQNKLGLRDCNQEVE 451 Query: 1497 ESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQK 1556 + LN+Q+++L EE+ + + Q + + + L L + + ++ Sbjct: 452 Q---LNQQISKLKSEKEEKERENGQNQIKFQEMKSKYNDLKQSYQELSDQYQRDQQMNKQ 508 Query: 1557 HVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDLAMYMLHQ 1598 V K+ + + + LD V + EL+ ++ Q Sbjct: 509 IVQSLQTQKEDFENRNSEQQSLFHLDLVSQQELETQQQLIKQ 550 >UniRef50_UPI0000F1EC3A Cluster: PREDICTED: hypothetical protein; n=4; Danio rerio|Rep: PREDICTED: hypothetical protein - Danio rerio Length = 2775 Score = 158 bits (384), Expect = 1e-36 Identities = 226/1141 (19%), Positives = 486/1141 (42%), Gaps = 81/1141 (7%) Query: 475 VNEIAKVQEQLKQEL---NDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKV-K 530 ++ + K +E+L L N E++ + K E+ K+AE ++ DE++ + KV + Sbjct: 916 IDGLLKEKEELLDHLEKRNTELEKLQTKSAAEQ-KAAELRLRGACDEVERWKERENKVQR 974 Query: 531 SNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDS 590 +L K +++ + + +E ++++ + ++ E+ L+L L + Sbjct: 975 EKEELNQKFLERVERESQNLEITQREKAKMSDLMKKKEDEIRRRGEDIEELKLKLQSNEK 1034 Query: 591 G-RMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQ 649 +E ++ +K +E+ ET K + L+ +K D ++E Q+K DE E + + Sbjct: 1035 TIESLEIELQQKET-LESRVETLEKLNTQLKEKKLDKIRENESRQKKRDEQEREKEVRWR 1093 Query: 650 LQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTI----KDLE----- 700 Q +Q + + L+ +ID L K+ ++L++E + D EQL T+ + LE Sbjct: 1094 RQLEQKDEGL--IELKSRIDELIGEKEHISLLVEEREKDIEQLQSTLSTEKRALELRLKE 1151 Query: 701 -NDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQE 759 D + + +++ + +++ + ++SELL + E Q + + + +IQ Sbjct: 1152 ARDNAEWWKRRAGNMEKVKESVNRVAEREKTELSELLREREEEVQKREEVISDLKNRIQS 1211 Query: 760 RDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQ 819 ++ IE +E+++ + ++ L E I+ M++R +++ D++ L+E++K + Sbjct: 1212 LEVIIEKLETDIEQKNEQLELLNEQISQMKEREIEDQKELDRMQENLKEQEKQLKR---E 1268 Query: 820 EDEL-VNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNA 878 D L + + V+ + + ++E+ IE + EL + +E + + L N Sbjct: 1269 LDHLNIKMVGVIQEKEELLER----IEERDGELTELQVKFTQEQRMFEQKLKAEHAEVNR 1324 Query: 879 LVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIES 938 K +AE E + + RD E ++ E +++K+ E+L Q + Sbjct: 1325 CKAK-----IAEMEQDQVNLKERDEEQRKRQKMEER----YREQKQTEEL-----VQKDV 1370 Query: 939 AIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQT 998 +R K+ E+ + IE ++ + QE L + EE + K +Q++ Sbjct: 1371 EVRQLKLKIEELNQEIEQDRRIRMEQQEDLEQQTALLRDAEE----EARTLKKTLQQKDK 1426 Query: 999 QSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLE 1058 + D ++ K LLK+K E N K+ ++ + + +L +L Sbjct: 1427 EERD----RLHHEEKEKTLLKEKLHEAEQRNIKVLSSLQEIETTLEKERYQLRGKEERLM 1482 Query: 1059 NMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELK---------ETKLTFEMNIPKT 1109 EE+ + ++ K+ EEL L+ EQ ++K L+ E +L+ + + Sbjct: 1483 ECNEELFLIKRERDQEKESIEELNKLIGEQGKEVKTLRGKLDERLEEEGRLSKLLQNQRV 1542 Query: 1110 EGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQ 1169 E ++ S E + ++ + L+ Q +E + ++ L+ + TE+ Sbjct: 1543 EVQVLESRAENIEEEKQQLKRSLSQIEEEKRHLETQLTDEKV-DKERLRVRLEDQATEVT 1601 Query: 1170 ECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVD 1229 + KI++ E ++L + V + E+ LS + +S + + + Sbjct: 1602 K-LNKILEEERKLSQLLQNSRVEAQMFESRAQNTEEEKQLLKRSLSQIEREKSRLETQLT 1660 Query: 1230 QRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTM 1289 + +L K L ++ + K + ++ ++ E K QLL + + Q ++ + Sbjct: 1661 DEKMDKEKL-KARLEDQDKEVTKLKEKMN-EILEEERKLSQLLQNSRVEAQMLESRAENI 1718 Query: 1290 E-QVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDE--KVAFXXXXXXXXXXXX 1346 E + L+ L EE R+L + D E LR+ +ED+ +V Sbjct: 1719 EVEKQQLKRSLTQIEEEKRHLGTQLTDEKMDKERLRAWVEDQATEVTKLKEKLSEMIEEE 1778 Query: 1347 XXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELT 1406 L ++ + E NI EE QL +S ++ D + L Sbjct: 1779 RKLSQLLQNSRVEAHILESRTENIEEEKQQLTRSLTQIEKEKRHLETQLTDEKMDKERLR 1838 Query: 1407 HQLELKDSEI---YQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILR 1463 +L+ + +E+ +K +E + + +N R + E R E+ T E++ +L + Sbjct: 1839 ARLKDQATEVTKLKEKLNEMIEEERKLSQLLQNSRVEAQMLESRAEN-TIEEKQQLKRVL 1897 Query: 1464 LKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQ 1523 ++ E ET + +I+R +L L + TE L + +LNK +E+E ++ Sbjct: 1898 SQVEEEKRLLETQLTDEKIDRERLKARLEDQATEVTKLKE---KLNKMVEDE----RKLS 1950 Query: 1524 TALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQL-DNTMNKELLD 1582 L+N ++E L NL+ ++++ ++ + K+ + QL D +++E L Sbjct: 1951 HLLQNSQVETQMLESRTENLEE----EKQQLKRSLTQIEEEKRCLETQLTDEKIDRERLR 2006 Query: 1583 A 1583 A Sbjct: 2007 A 2007 Score = 156 bits (379), Expect = 4e-36 Identities = 246/1341 (18%), Positives = 567/1341 (42%), Gaps = 101/1341 (7%) Query: 212 EDTKQQMTKMQENFIAMEAEWK---DEKQRLLKDIESKDVRISSLEEANKLLEAARFEIS 268 E T+++ KM + E E + ++ + L ++S + I SLE + E + Sbjct: 995 EITQREKAKMSDLMKKKEDEIRRRGEDIEELKLKLQSNEKTIESLEIELQQKETLESRVE 1054 Query: 269 LEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKI 328 Q E+ +Q E + ++E+K I + + + I Sbjct: 1055 TLEKLNTQLKEKKLDKIRENESRQKKRDEQEREKEVRWRRQLEQKDEGLIELKSRIDELI 1114 Query: 329 ELLEHLNCQIRQTNKELENKLATMGTESKAVS---SPSKKGSPLISRKSGRNTASKMKSP 385 EH++ + + K++E +T+ TE +A+ ++ + R++G K+K Sbjct: 1115 GEKEHISLLVEEREKDIEQLQSTLSTEKRALELRLKEARDNAEWWKRRAG--NMEKVKES 1172 Query: 386 WSQLSSETLNQDTD-KKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXG 444 ++++ + ++ + + E+ K E VI L + E +I + +T Sbjct: 1173 VNRVAEREKTELSELLREREEEVQKREEVISDLKNRIQSLEVIIEKLETDI--------- 1223 Query: 445 KDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQ---ELNDEIKDVNVKDL 501 + QL+L ++Q + ED E+ ++QE LK+ +L E+ +N+K + Sbjct: 1224 -EQKNEQLELLNEQISQMKE-----REIEDQKELDRMQENLKEQEKQLKRELDHLNIK-M 1276 Query: 502 IEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLT 561 + ++ EE + ++ +E D + ++K Q Q+ + K + Sbjct: 1277 VGVIQEKEELLERI-EERDGELTEL-------QVKFTQEQRMFEQKLKAEHA-------- 1320 Query: 562 EELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISL--- 618 E++ K+AE+E+++ NL+ + + +E + Y++ + E L + ++ L Sbjct: 1321 -EVNRCKAKIAEMEQDQVNLKERDEEQRKRQKME-ERYREQKQTEELVQKDVEVRQLKLK 1378 Query: 619 LESQKFDLVQELHILQQKYDEVEDKLADISQLQSD-QVCSEIKSVHLEEQIDALSASKKE 677 +E ++ Q+ I ++ +++E + A + + + + + +E+ D L +KE Sbjct: 1379 IEELNQEIEQDRRIRMEQQEDLEQQTALLRDAEEEARTLKKTLQQKDKEERDRLHHEEKE 1438 Query: 678 LALVIENLKLDKE---QLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISE 734 L+ E L ++ ++ +++++E E +L+ + M+ ++L + E+ E Sbjct: 1439 KTLLKEKLHEAEQRNIKVLSSLQEIETTLEKERYQLRGKEERLMECNEELFLIKRERDQE 1498 Query: 735 LLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYS 794 K + EE +K+ + G + K R E +E E + + + V+E R + Sbjct: 1499 ---KESIEELNKLIGEQGKEVKTL-RGKLDERLEEE-GRLSKLLQNQRVEVQVLESRAEN 1553 Query: 795 LERKADQLGSYLQ--EKQKAYSEYTIQEDEL-VNRLAVLMDHDRVVEKQLLEIEHENKEL 851 +E + QL L E++K + E + ++++ RL V ++ +L +I E ++L Sbjct: 1554 IEEEKQQLKRSLSQIEEEKRHLETQLTDEKVDKERLRVRLEDQATEVTKLNKILEEERKL 1613 Query: 852 QKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRIT 911 + Q E Q + + ++ L ++ E E ++ +TQL D + + +++ Sbjct: 1614 SQLLQNSRVEAQMFESRAQNTEEEKQLLKRSLSQ---IEREKSRLETQLTDEKMDKEKLK 1670 Query: 912 H--EHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKN 969 E Q V K KE + +E ++ +++ +V + E E +E + Q+ K Sbjct: 1671 ARLEDQDKEVTKLKEKMNEILEEERKLSQLLQNSRVEAQMLESRAE---NIEVEKQQLKR 1727 Query: 970 NIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALN 1029 ++ + EE + +L D+ + K++ ++ + E E+ KL L + EE L+ Sbjct: 1728 SLTQIE---EEKRHLGTQLTDEKMDKERLRA--WVEDQATEVTKLKEKLSEMIEEERKLS 1782 Query: 1030 QKINNAQVS---YMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVR 1086 Q + N++V S + E + Q T L +E+E + + QL D K E L+ ++ Sbjct: 1783 QLLQNSRVEAHILESRTENIEEEKQQLTRSLTQIEKEKRHLETQLTDEKMDKERLRARLK 1842 Query: 1087 EQDDQIKELK---------ETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXX 1137 +Q ++ +LK E KL+ + + E ++ S E ++ + Sbjct: 1843 DQATEVTKLKEKLNEMIEEERKLSQLLQNSRVEAQMLESRAENTIEEKQQLKRVLSQVEE 1902 Query: 1138 XXXXLKVQEEEEFIQE---RSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQE 1194 L+ Q +E I ++ L++Q+ ++ T+L+E K+++ E + L + +Q Sbjct: 1903 EKRLLETQLTDEKIDRERLKARLEDQATEV-TKLKEKLNKMVEDERKLSHLLQN---SQV 1958 Query: 1195 QINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTE 1254 + L+S+ E L E L ++ ++ Q E ++ ++ L R DFQK + Sbjct: 1959 ETQMLESRTENLEEEKQQLKRSLTQIEEEKRCLETQLTDE--KIDRERLRARLEDFQKDQ 2016 Query: 1255 HELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYA 1314 ++ + E+L V+ ++ + + + L+D+ R +++ + Sbjct: 2017 ---QILFEEKMGRAEKLGSRVRELEEQRDHLSAELRRKEREMEVLRDETLRERREKDRIS 2073 Query: 1315 DVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEEN 1374 +++ + + + + + ++ + + K+M+E + + +E Sbjct: 2074 SLLSDAKERKESLSVQVDSLQEQLVSLSRSKEQTKLKIQEQKEQNKEMREGLVAGL-QEM 2132 Query: 1375 AQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTI-TLTQRNDE 1433 A LK+ + + + +++ + + +K + I K + + L ++ E Sbjct: 2133 ATLKELLEESHREGERLRSMMQERKDELVR-SREEGIKVAHIEAKDLQLKVQMLEKQKQE 2191 Query: 1434 FENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNV 1493 E Q VE K+ + +++ +L + K+ +++++ E E + L++ Sbjct: 2192 LETTLQLQVEQLKKKNEEGMQEKEQLQQRQEKLEGELMAMKSVKEHREAELTRAKARLDI 2251 Query: 1494 KITESVSLNKQVAELNKALEE 1514 + L+ AE K EE Sbjct: 2252 LEDQRTELSSLAAERTKDAEE 2272 Score = 139 bits (337), Expect = 5e-31 Identities = 233/1236 (18%), Positives = 527/1236 (42%), Gaps = 89/1236 (7%) Query: 151 IKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXX 210 +++++ +S L+ +++ +E I L+ I +K++ +E N+ + Sbjct: 1195 VQKREEVISDLKNRIQSLEVIIEKLETDIEQKNEQLELLNEQISQMKEREIEDQKELDRM 1254 Query: 211 XEDTKQQMTKMQENFIAMEAEWK---DEKQRLLKDIESKDVRISSLEEANKLLEAARFEI 267 E+ K+Q +++ + + EK+ LL+ IE +D ++ L+ E FE Sbjct: 1255 QENLKEQEKQLKRELDHLNIKMVGVIQEKEELLERIEERDGELTELQ-VKFTQEQRMFEQ 1313 Query: 268 SL--EHSKL----AQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANM 321 L EH+++ A+ E +Q +E E+ + EE ++ + Sbjct: 1314 KLKAEHAEVNRCKAKIAEMEQDQVNLKERDEEQRKRQKMEERYREQKQTEELVQKDV-EV 1372 Query: 322 TELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTAS- 380 +L KIE L Q R+ E + L + ++ + +K Sbjct: 1373 RQLKLKIEELNQEIEQDRRIRMEQQEDLEQQTALLRDAEEEARTLKKTLQQKDKEERDRL 1432 Query: 381 KMKSPWSQLSSETLNQDTDKKINK-NEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXX 439 + L E L++ + I + + ++E ++ L KE + E + Sbjct: 1433 HHEEKEKTLLKEKLHEAEQRNIKVLSSLQEIETTLEKERYQLRGKEERLMECNEELFLIK 1492 Query: 440 XXXXGKDTLIAQL-QLEHQQHMEGPSLI-HVGTNTEDVNEIAKVQEQLKQELND-EIKDV 496 + I +L +L +Q E +L + E+ ++K+ + + E+ E + Sbjct: 1493 RERDQEKESIEELNKLIGEQGKEVKTLRGKLDERLEEEGRLSKLLQNQRVEVQVLESRAE 1552 Query: 497 NVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKE 556 N+++ ++LK + QI + ++ + K +++L+ + +K+ + ++ Sbjct: 1553 NIEEEKQQLKRSLSQIEEEKRHLETQLTDEKVDKERLRVRLEDQATEVTKLNKILEEERK 1612 Query: 557 IVRLTE----ELHHLSQKVAELEEEKGNLQLHLVDYDSGRM-IESDVYKKMIEMENLA-- 609 + +L + E + EEEK L+ L + + +E+ + + ++ E L Sbjct: 1613 LSQLLQNSRVEAQMFESRAQNTEEEKQLLKRSLSQIEREKSRLETQLTDEKMDKEKLKAR 1672 Query: 610 -ETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQI 668 E + K ++ L+ + ++++E L Q +++ + L+S E++ L+ + Sbjct: 1673 LEDQDKEVTKLKEKMNEILEEERKLSQL---LQNSRVEAQMLESRAENIEVEKQQLKRSL 1729 Query: 669 DALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLE--K 726 + K+ L + + K+DKE+L ++D + + KL I+E L+ L+ + Sbjct: 1730 TQIEEEKRHLGTQLTDEKMDKERLRAWVEDQATEVTKLKEKLSEMIEEERKLSQLLQNSR 1789 Query: 727 MSAEKISELLAKINHEEQ--SKIQTQFGIDAKIQERDLYIENIESE-----LSKYKSRIC 779 + A + I E+Q ++ TQ + + E L E ++ E L + + Sbjct: 1790 VEAHILESRTENIEEEKQQLTRSLTQIEKEKRHLETQLTDEKMDKERLRARLKDQATEVT 1849 Query: 780 RLEESIAVM--EDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVV 837 +L+E + M E+R+ S + ++ + + E + +E TI+E + + R+ ++ Sbjct: 1850 KLKEKLNEMIEEERKLSQLLQNSRVEAQMLESR---AENTIEEKQQLKRVLSQVEE---- 1902 Query: 838 EKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQ 897 EK+LLE + ++++ ++ E+Q +++ +++ N +VE + ++++ + Sbjct: 1903 EKRLLETQLTDEKIDRERLKARLEDQATEVT--KLKEKLNKMVEDERKLSHL-LQNSQVE 1959 Query: 898 TQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIE-Y 956 TQ+ LES + + E Q L K+ + +E E +E+ + D+K+ E+ +E + Sbjct: 1960 TQM--LESRTENLEEEKQQL----KRSLTQIEEEKRC-LETQLTDEKIDRERLRARLEDF 2012 Query: 957 VTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSP--DYTEQYINEINKL 1014 + +E E L V EL + L + +K++ D T + E +++ Sbjct: 2013 QKDQQILFEEKMGRAEKLGSRVRELEEQRDHLSAELRRKEREMEVLRDETLRERREKDRI 2072 Query: 1015 NALLKQKDEEIIALNQKINNAQVSYMSMV-SDYESKLAQFTTKLENME---------EEM 1064 ++LL E +L+ ++++ Q +S+ S ++KL K +N E +EM Sbjct: 2073 SSLLSDAKERKESLSVQVDSLQEQLVSLSRSKEQTKLKIQEQKEQNKEMREGLVAGLQEM 2132 Query: 1065 QRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDD 1124 + + L +S + E L+ +++E+ D++ +E + + E + ++ + Sbjct: 2133 ATLKELLEESHREGERLRSMMQERKDELVRSREEGI----KVAHIEAKDLQLKVQMLEKQ 2188 Query: 1125 ANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTE 1184 ++ LK ++ EE +QE+ LQ++ KL EL + E T Sbjct: 2189 KQELETTLQLQVEQ---LK-KKNEEGMQEKEQLQQRQEKLEGELMAMKSVKEHREAELTR 2244 Query: 1185 LTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEI---AELWKQ 1241 + ++Q +L S + + + L + +LR + R E EL ++ Sbjct: 2245 AKARLDILEDQRTELSSLAAERTKDAEELSNRFRDLRLEADRLREDRIREKNNWEELKRE 2304 Query: 1242 HLAQREAD-----FQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQ 1296 + ++ A +KT E ++ + KYE + + S + + + Q+ + Sbjct: 2305 NKEKQNALEELELLRKTLMEKEKEMKLVKEKYE---NEKRRSERFQQGDEQNVRQIELVS 2361 Query: 1297 NKLQDKEEHLRNLQEK-YADVINQIEILRSEIEDEK 1331 +L+DKE L +++EK Y + ++ L+ + EDEK Sbjct: 2362 ERLRDKETELESIREKAYKEQSARLR-LQDQFEDEK 2396 Score = 116 bits (278), Expect = 7e-24 Identities = 241/1320 (18%), Positives = 559/1320 (42%), Gaps = 131/1320 (9%) Query: 312 EKGSLEIANMTELTKK-IELLEHLN---CQIRQTN------KELENKLATMGTESKAVSS 361 EK SLE +T+L + +EL E N QI+ T KE+ + L E++ ++ Sbjct: 437 EKESLE-QRITQLESEWVELQEQTNQGALQIKHTQELLNSEKEIVSSLRGQVEEAEKLTE 495 Query: 362 PSKKGSPLISRKSGRNTASKMKSP---WSQLSSETLNQDTDKKINKNEIAKLEMVIQSLN 418 +K + + R+ + +++ ++ +E L + +L + +L Sbjct: 496 ELRKENEHMRRQREKQEEDRIQQDRERHKRMEAEMLESAQLCERESRTRLELHRLQVALE 555 Query: 419 KDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEI 478 ++ +D+ E + +++L+AQ ++Q E L G E + + Sbjct: 556 RETLDRARAEQEAEQAKDALIKA---RESLLAQSSGQNQLKRE---LAGAGDALEKMAAL 609 Query: 479 AKVQEQLKQELNDEIK--DVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLK 536 + + K+EL + V + ++++ + L+ E+ A + + +++ + Sbjct: 610 NEALAKDKRELGVRSLQLETEVAEAQAQIQAFGTETAGLHRELKAMSLEVHELRQRRESD 669 Query: 537 LKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIES 596 LK +Q+ + ++ ++ E+ R + ++ A E++ + Q + + Sbjct: 670 LKALQQLREREREL-ENELELEREDRQ----REQTARTEDKSTDEQKISELTEQCSTVMK 724 Query: 597 DVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQ-- 654 ++ +E+ AE + +A E ++ DL++E L+ +E + +++Q++ + Sbjct: 725 ELQSVKVELLKAAELQRRA----ERERDDLMRESQRLEDTVCTLEREKEELAQVKEELRG 780 Query: 655 --VCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQN 712 VC + + +EQ L +L + ++ L K+ L G I+ L+ D E + + Sbjct: 781 VVVCLQKQMAQAQEQTSGLELKCIQLQMQVDTLTQTKDVLQGEIQCLQTDLERETAQKER 840 Query: 713 YIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELS 772 +QE+++ K E+ SE EQ ++ + +R E + E Sbjct: 841 ELQESIEERRKFEREIENWKSECKKFQRDVEQESENSKIQAEESKTDR----ERWQKERE 896 Query: 773 KYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQ----EKQKAYSEYTIQEDELVNRLA 828 + + + + + ++ +R L ++ ++L +L+ E +K ++ ++ RL Sbjct: 897 SLSAELGQKDGEVEILRNRIDGLLKEKEELLDHLEKRNTELEKLQTKSAAEQKAAELRLR 956 Query: 829 VLMDHDRVVEKQLLEIEHENKELQKKNQILLE-ENQNLQISLSDMQQHYNALVEKANRTD 887 D +++ +++ E +EL +K +E E+QNL+I+ EKA +D Sbjct: 957 GACDEVERWKERENKVQREKEELNQKFLERVERESQNLEITQR----------EKAKMSD 1006 Query: 888 LAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQ--IESAIRDKKV 945 L + + + + + D+E E + + +K IE LEIE + +ES + + Sbjct: 1007 LMKKKEDEIRRRGEDIE--------ELKLKLQSNEKTIESLEIELQQKETLESRVETLEK 1058 Query: 946 LNEKY-EKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYT 1004 LN + EK ++ + + E++ Q+ ++ E E + LE D+ + + +++ Sbjct: 1059 LNTQLKEKKLDKIRENESR-QKKRDEQER---EKEVRWRRQLEQKDEGLIELKSR----I 1110 Query: 1005 EQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEM 1064 ++ I E ++ L+++++++I L ++ + + + + + + NME+ Sbjct: 1111 DELIGEKEHISLLVEEREKDIEQLQSTLSTEKRALELRLKEARDNAEWWKRRAGNMEKVK 1170 Query: 1065 QRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDD 1124 + V++ +++ EL L+RE+++++++ +E + I E +I +E + Sbjct: 1171 ESVNRV---AEREKTELSELLREREEEVQKREEVISDLKNRIQSLE--VIIEKLETDIEQ 1225 Query: 1125 ANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKII-------- 1176 N ++++++E + + L+EQ +L EL K++ Sbjct: 1226 KNEQLELLNEQISQMKEREIEDQKELDRMQENLKEQEKQLKRELDHLNIKMVGVIQEKEE 1285 Query: 1177 ---QLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGF 1233 ++E + ELT V ++ + KL+ + E + + +AE+ V+ + Sbjct: 1286 LLERIEERDGELTELQVKFTQEQRMFEQKLKAEHAEVNRCKAKIAEME---QDQVNLKER 1342 Query: 1234 EIAELWKQHLAQREADFQKTEHELR--VQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQ 1291 + + +Q + +R + ++TE ++ V++ + K E+L ++ + + +EQ Sbjct: 1343 DEEQRKRQKMEERYREQKQTEELVQKDVEVRQLKLKIEELNQEIEQDRRIRMEQQEDLEQ 1402 Query: 1292 VTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXD 1351 T+L L+D EE R L++ + E EK Sbjct: 1403 QTAL---LRDAEEEARTLKKTLQQKDKEERDRLHHEEKEKTLLKEKLHEAEQRNIKVLSS 1459 Query: 1352 LR-----TENQSYK-QMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLEL 1405 L+ E + Y+ + +E+ ++ NEE +K+ + + +V L Sbjct: 1460 LQEIETTLEKERYQLRGKEERLMECNEELFLIKRERDQEKESIEELNKLIGEQGKEVKTL 1519 Query: 1406 THQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLK 1465 +L D + ++ + + +N R ++ E R E++ EK+ +L + Sbjct: 1520 RGKL---DERLEEE--------GRLSKLLQNQRVEVQVLESRAENIEEEKQ-QLKRSLSQ 1567 Query: 1466 MHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTA 1525 + E H ET + ++++ E L V++ + + +V +LNK LEEE ++ Sbjct: 1568 IEEEKRHLETQLTDEKVDK----ERLRVRLEDQAT---EVTKLNKILEEE----RKLSQL 1616 Query: 1526 LENQEIEIVTLNDEITNLQ---NMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLD 1582 L+N +E N + +++ S S+I++ S Q DE++D K L+ Sbjct: 1617 LQNSRVEAQMFESRAQNTEEEKQLLKRSLSQIEREKSRLE--TQLTDEKMDKEKLKARLE 1674 Score = 72.9 bits (171), Expect = 7e-11 Identities = 191/995 (19%), Positives = 409/995 (41%), Gaps = 76/995 (7%) Query: 146 HLSNTIKEKDNALSVLQVKMKIMETTILDLQEKIN---EKDQIIEAKNKATTXXXXXXXX 202 HL + ++ L+ ++K T + L+EK+N E+++ + + + Sbjct: 1822 HLETQLTDEKMDKERLRARLKDQATEVTKLKEKLNEMIEEERKLSQLLQNSRVEAQMLES 1881 Query: 203 XXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEK---QRLLKDIESKDVRISSL-EEANK 258 + K+ +++++E +E + DEK +RL +E + ++ L E+ NK Sbjct: 1882 RAENTIEEKQQLKRVLSQVEEEKRLLETQLTDEKIDRERLKARLEDQATEVTKLKEKLNK 1941 Query: 259 LLEAARFEISLEHSKLAQELE-QXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLE 317 ++E R L H ++E Q K+S+ EEK +E + + E Sbjct: 1942 MVEDER---KLSHLLQNSQVETQMLESRTENLEEEKQQLKRSLTQIEEEKRCLETQLTDE 1998 Query: 318 IANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSG-- 375 + L ++E + + QI +E + +G+ + + S + RK Sbjct: 1999 KIDRERLRARLEDFQK-DQQI--LFEEKMGRAEKLGSRVRELEEQRDHLSAELRRKEREM 2055 Query: 376 ---RNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISE-K 431 R+ + + ++SS + K+ ++ L+ + SL++ + I E K Sbjct: 2056 EVLRDETLRERREKDRISSLLSDAKERKESLSVQVDSLQEQLVSLSRSKEQTKLKIQEQK 2115 Query: 432 DTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELND 491 + G + +L + H EG L + +D E+ + +E+ + + Sbjct: 2116 EQNKEMREGLVAGLQEMATLKELLEESHREGERLRSMMQERKD--ELVRSREEGIKVAHI 2173 Query: 492 EIKDVNVK-DLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKV 550 E KD+ +K ++EK K E QL E KN + K +L+Q Q+ ++ Sbjct: 2174 EAKDLQLKVQMLEKQKQELETTLQLQVE-QLKKKN--EEGMQEKEQLQQRQEKLEGELMA 2230 Query: 551 SDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKM-IEMENLA 609 S KE EL ++ LE+++ L + S+ ++ + +E + L Sbjct: 2231 MKSVKE--HREAELTRAKARLDILEDQRTELSSLAAERTKDAEELSNRFRDLRLEADRLR 2288 Query: 610 ETRLKAISLLE------SQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVH 663 E R++ + E +K + ++EL +L++ E E ++ +L ++ +E + Sbjct: 2289 EDRIREKNNWEELKRENKEKQNALEELELLRKTLMEKEKEM----KLVKEKYENEKRRSE 2344 Query: 664 LEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDK 723 +Q D + +++ LV E L+ DKE +I++ ++ +LQ+ ++ +T K Sbjct: 2345 RFQQGD--EQNVRQIELVSERLR-DKETELESIREKAYKEQSARLRLQDQFEDEKRVTKK 2401 Query: 724 LEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEE 783 L EK+ E L K+ E ++K++ ++++ + K S L + Sbjct: 2402 LR----EKL-ETLEKVKQEMKTKMENDIRYFRDSEKKNNGL--------KMDSGHGTLAD 2448 Query: 784 SIAVMEDRRYSLE-RKADQLGSYLQEKQKAYSEYTIQEDEL---VNRLAVLMDHDRVVEK 839 S+ + + R ++ +AD L L +K + I+ + L ++RL L+ + ++ Sbjct: 2449 SLEINAEYRSHVKLLEADTLRKDLTKKDQEIRRLRIKAETLQTEIDRLHSLLKNGN-MKT 2507 Query: 840 QLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQ 899 E E ++E Q+ + ILLE+ + ++ L + AL E+A + + + Sbjct: 2508 GPTENEDWDREKQQVSTILLEKEERDRL-LREKDVEVYALKERAEE---MSKDRDRVRIA 2563 Query: 900 LRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQ 959 L E+ L I ++ + + K++ +I + + ++ + + V Q Sbjct: 2564 LEKTEAML--IYYKERLGHQEHKRKQTGGDISLEKVSADELDTESAVHGRLSAMQQAVAQ 2621 Query: 960 LEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLK 1019 LE Q + +L +E L L + Q + + + ++E L+ + Sbjct: 2622 LEVQQNLLEKKNSHLEKKIERLRTERQHLRETLTQVELERGKLRRQLSLSEAGVLDQSVG 2681 Query: 1020 QKDEEIIALNQKIN--NAQVSYMSMV--SDYESKLAQFTTKLENMEE--EMQRVSKQLLD 1073 D E+ L + N QV ++ ++ D+ + L+N + +++ + L Sbjct: 2682 TDDAELKHLRVRANELEEQVHHLRLMLAVDHRQRAEFIDRSLKNSQSLMSLRQDLNESLS 2741 Query: 1074 SKQHNEELQILVREQ---DDQIKELKETKLTFEMN 1105 + L +L E D I+E +E +LTF + Sbjct: 2742 AVSQRPVLSVLESETQRLDRSIRE-EELRLTFSQS 2775 Score = 62.1 bits (144), Expect = 1e-07 Identities = 126/630 (20%), Positives = 259/630 (41%), Gaps = 46/630 (7%) Query: 952 KNIEYVTQLEAQLQEYKNNIENLNMNVEELN----KMNLELIDKH---VQKQQTQSPDYT 1004 K+ E +E++ E +N I LNM V+ L K E+ +H ++++Q Q + Sbjct: 299 KSSELKADIESETLELRNRITELNMTVKALESEREKQEEEMERRHRHEMEREQEQERKWE 358 Query: 1005 EQYINEINKLNALLKQKDEEIIALNQKIN--NAQVSYMSMVSD----YESKLAQFTTKLE 1058 Q E N + K L+QK++ ++ +S SD S +AQ T L+ Sbjct: 359 RQMELERNFESVCQAVKTLSRALLSQKMSGESSSLSADDASSDGLCSVLSVIAQAETALQ 418 Query: 1059 NMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMI----- 1113 E+E+Q L E L+ + + + + EL+E + I T+ ++ Sbjct: 419 WREQEVQEAQMSLRRLGTEKESLEQRITQLESEWVELQEQTNQGALQIKHTQELLNSEKE 478 Query: 1114 ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYT 1173 I S++ ++A + + ++EE+ IQ+ +E+ ++ E+ E Sbjct: 479 IVSSLRGQVEEAEKLTEELRKENEHMRRQREKQEEDRIQQD---RERHKRMEAEMLES-A 534 Query: 1174 KIIQLETLNTELTGHDV-VNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRG 1232 ++ + E+ T L H + V E+ +++ EQ + + L E + SS +Q Sbjct: 535 QLCERES-RTRLELHRLQVALERETLDRARAEQEAEQAKDALIKARESLLAQSSGQNQLK 593 Query: 1233 FEIA---ELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETN----- 1284 E+A + ++ A EA K + EL V+ E++ + +Q+ E Sbjct: 594 RELAGAGDALEKMAALNEA-LAKDKRELGVRSLQLETEVAEAQAQIQAFGTETAGLHREL 652 Query: 1285 KIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXX 1344 K +++E V L+ + + + L+ L+E+ ++ N++E+ R + + E+ A Sbjct: 653 KAMSLE-VHELRQRRESDLKALQQLRERERELENELELEREDRQREQTA----RTEDKST 707 Query: 1345 XXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLE 1404 +L TE S + QS+ + A+L++ + R+ D + Sbjct: 708 DEQKISEL-TEQCSTVMKELQSVKVELLKAAELQRRAERERDDLMRESQRLEDTVCTLER 766 Query: 1405 LTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEK---ESELAI 1461 +L E+ + Q ++ + + ++ + +++ LT K + E+ Sbjct: 767 EKEELAQVKEELRGVVVCLQKQMAQAQEQTSGLELKCIQLQMQVDTLTQTKDVLQGEIQC 826 Query: 1462 LRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAE--LNKALEEEVAKT 1519 L+ + E +ES ER K E+ +E + V + N ++ E +KT Sbjct: 827 LQTDLERETAQKERELQESIEERRKFEREIENWKSECKKFQRDVEQESENSKIQAEESKT 886 Query: 1520 N--EMQTALENQEIEIVTLNDEITNLQNMV 1547 + Q E+ E+ + E+ L+N + Sbjct: 887 DRERWQKERESLSAELGQKDGEVEILRNRI 916 >UniRef50_Q9FJ35 Cluster: Myosin heavy chain-like protein; n=2; Arabidopsis thaliana|Rep: Myosin heavy chain-like protein - Arabidopsis thaliana (Mouse-ear cress) Length = 1305 Score = 158 bits (384), Expect = 1e-36 Identities = 223/1131 (19%), Positives = 491/1131 (43%), Gaps = 74/1131 (6%) Query: 484 QLKQ-ELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQK 542 Q+K+ E + E + V D + L +AEE+ L+ +I A N I+ N +L Sbjct: 67 QVKELEAHIESSEKLVADFTQSLNNAEEEKKLLSQKI-AELSNEIQEAQNTMQELMSESG 125 Query: 543 TIDNFSKVSDSNKEIVRLTEELHHL--SQKVAELEEEKGNLQLHLVDYDSGRMIESDVYK 600 + V + +R E+H S + +ELE + + + + D S + ++ Sbjct: 126 QLKESHSVKERELFSLRDIHEIHQRDSSTRASELEAQLESSKQQVSDL-SASLKAAEEEN 184 Query: 601 KMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQL-QSDQVCSEI 659 K I +N+ ET K + ++ +L+ EL L+ + E E +L+ + ++ ++ Q S I Sbjct: 185 KAISSKNV-ETMNK-LEQTQNTIQELMAELGKLKDSHREKESELSSLVEVHETHQRDSSI 242 Query: 660 KSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMD 719 LEEQ+++ EL + N + +K+ L I +L N+ ++ N +Q + E+ Sbjct: 243 HVKELEEQVESSKKLVAELNQTLNNAEEEKKVLSQKIAELSNEIKEAQNTIQELVSESGQ 302 Query: 720 LTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRIC 779 L + + S L I+ Q + T ++ E + +E+ E +S + Sbjct: 303 LKESHSVKDRDLFS--LRDIHETHQRESST------RVSELEAQLESSEQRISDLTVDLK 354 Query: 780 RLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDH-DRVVE 838 EE + + + K +Q + ++E E + E + L+ L+ D+ V Sbjct: 355 DAEEENKAISSKNLEIMDKLEQAQNTIKELMDELGELKDRHKEKESELSSLVKSADQQVA 414 Query: 839 KQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQT 898 +++ +E + +Q +L+ + +Q + +Q+H + + + E E T Sbjct: 415 DMKQSLDNAEEEKKMLSQRILDISNEIQEAQKTIQEHMSESEQLKESHGVKERELTG--- 471 Query: 899 QLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVT 958 LRD+ +R + + + + K +E ++ + + +A +KK L+ + + + Sbjct: 472 -LRDIHETHQRESSTRLSELETQLKLLEQRVVDLSASLNAAEEEKKSLSSMILEITDELK 530 Query: 959 QLEAQLQEYKNNI-ENLNMNVEELNKMN--LELIDKHVQKQQTQSPDY---TEQYINEIN 1012 Q ++++QE + E+ + ++ N+++ +E+ + H + +Q + E ++ Sbjct: 531 QAQSKVQELVTELAESKDTLTQKENELSSFVEVHEAHKRDSSSQVKELEARVESAEEQVK 590 Query: 1013 KLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLL 1072 +LN L +EE L+Q+I+ + S + +L+ + +L+ E L Sbjct: 591 ELNQNLNSSEEEKKILSQQISEMSIKIKRAESTIQ-ELSSESERLKGSHAEKDNELFSLR 649 Query: 1073 DSKQ-HNEELQILVREQDDQIK--ELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVD 1129 D + H EL +R + Q++ E + +L+ + + E +S+ I SD+ Sbjct: 650 DIHETHQRELSTQLRGLEAQLESSEHRVLELSESLKAAEEESRTMSTKISETSDELERTQ 709 Query: 1130 XXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHD 1189 LK Q E+ + +L E+ +K +++E + LE L E Sbjct: 710 IMVQELTADSSKLKEQLAEKE-SKLFLLTEKDSKSQVQIKELEATVATLE-LELESVRAR 767 Query: 1190 VVNQE-QINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQ---HLAQ 1245 +++ E +I + +EQL +N +++ ++EL ++ ++RG E++ L ++ + Q Sbjct: 768 IIDLETEIASKTTVVEQLEAQNREMVARISELEKTM----EERGTELSALTQKLEDNDKQ 823 Query: 1246 READFQKTEHE---LRVQLSAFESKYEQLLDSVQSSTQEETNKIVTME--------QVTS 1294 + + E LR +L + + E++ + ++E + KI ++ QV S Sbjct: 824 SSSSIETLTAEIDGLRAELDSMSVQKEEVEKQMVCKSEEASVKIKRLDDEVNGLRQQVAS 883 Query: 1295 LQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDE-KVAFXXXXXXXXXXXXXXXXDLR 1353 L ++ + E L E+ ++ ++QI L+ EI ++ KV +L Sbjct: 884 LDSQRAELEIQLEKKSEEISEYLSQITNLKEEIINKVKVHESILEEINGLSEKIKGRELE 943 Query: 1354 TENQSYKQMQ-EQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELK 1412 E ++ + ++ + EEN Q+ +N+ + ++ L Q Sbjct: 944 LETLGKQRSELDEELRTKKEENVQMHDKINVASSEIMALTELINNLKNELDSLQVQKSET 1003 Query: 1413 DSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANH 1472 ++E+ ++ E + + +++ +V++ LVE E L E+ ++ L + N Sbjct: 1004 EAELEREKQEKS----ELSNQITDVQKALVEQEAAYNTLE-EEHKQINELFKETEATLNK 1058 Query: 1473 YETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIE 1532 KE++ +L+EE ++T S + EE ++ + ++ EIE Sbjct: 1059 VTVDYKEAQ----RLLEERGKEVTSRDS--------TIGVHEETMESLRNELEMKGDEIE 1106 Query: 1533 IVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQG-RDEQLDNTMNKELLD 1582 TL ++I+N++ +R S+ K++ ++ ++ R E+ + + LL+ Sbjct: 1107 --TLMEKISNIEVKLRLSNQKLRVTEQVLTEKEEAFRKEEAKHLEEQALLE 1155 Score = 138 bits (334), Expect = 1e-30 Identities = 211/994 (21%), Positives = 431/994 (43%), Gaps = 102/994 (10%) Query: 607 NLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEE 666 N AE K++SL S+ D++Q+ Q E+ +L ++ + ++ V L + Sbjct: 2 NSAEEENKSLSLKVSEISDVIQQG---QTTIQELISELGEMKEKYKEKESEHSSLVELHK 58 Query: 667 QIDALSASK-KELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLE 725 + S+S+ KEL IE+ + ++ + E +K+ + K+ E + + ++ Sbjct: 59 THERESSSQVKELEAHIESSEKLVADFTQSLNNAEEEKKLLSQKIAELSNEIQEAQNTMQ 118 Query: 726 KMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERD--LYIENIESELSKYKSRICRLEE 783 ++ +E +L K +H + + +I +RD +E++L K ++ L Sbjct: 119 ELMSES-GQL--KESHSVKERELFSLRDIHEIHQRDSSTRASELEAQLESSKQQVSDLSA 175 Query: 784 SIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLE 843 S+ E+ ++ K + + L++ Q TIQE L+ L L D R E +L Sbjct: 176 SLKAAEEENKAISSKNVETMNKLEQTQN-----TIQE--LMAELGKLKDSHREKESELSS 228 Query: 844 IEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRT-DLAESESTKYQTQLRD 902 + ++ Q+ + I ++E L + + LV + N+T + AE E ++ + Sbjct: 229 LVEVHETHQRDSSIHVKE-------LEEQVESSKKLVAELNQTLNNAEEEKKVLSQKIAE 281 Query: 903 LESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEY-VTQLE 961 L + +K + Q L+ + + E ++ ++RD ++E +++ V++LE Sbjct: 282 LSNEIKEAQNTIQELVSESGQLKESHSVKDRDLF--SLRD---IHETHQRESSTRVSELE 336 Query: 962 AQLQEYKNNIENLNMNV---EELNKM----NLELIDKHVQKQQTQSPDYTEQYINEINKL 1014 AQL+ + I +L +++ EE NK NLE++DK Q Q T ++ ++E+ +L Sbjct: 337 AQLESSEQRISDLTVDLKDAEEENKAISSKNLEIMDKLEQAQNT-----IKELMDELGEL 391 Query: 1015 NALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDS 1074 K+K+ E+ S+V + ++A L+N EEE + +S+++LD Sbjct: 392 KDRHKEKESEL--------------SSLVKSADQQVADMKQSLDNAEEEKKMLSQRILDI 437 Query: 1075 KQHNEELQILVRE---QDDQIKE---LKETKLTFEMNIPKTEGMIISSTIEPMSDDANNV 1128 +E Q ++E + +Q+KE +KE +LT +I +T S+ + + + Sbjct: 438 SNEIQEAQKTIQEHMSESEQLKESHGVKERELTGLRDIHETHQRESSTRLSELETQLKLL 497 Query: 1129 DXXXXXXXXXXXXLKVQEEE------EFIQERSVLQEQSAKLNTELQECYTKIIQLET-L 1181 + + +++ E E Q + +L TEL E + Q E L Sbjct: 498 EQRVVDLSASLNAAEEEKKSLSSMILEITDELKQAQSKVQELVTELAESKDTLTQKENEL 557 Query: 1182 NTELTGHDVVNQEQINQLK-------SKLEQLNTENDNLLSTVAELRSSISSAVDQRGFE 1234 ++ + H+ ++ +Q+K S EQ+ N NL S+ E + +S + + + Sbjct: 558 SSFVEVHEAHKRDSSSQVKELEARVESAEEQVKELNQNLNSSEEE-KKILSQQISEMSIK 616 Query: 1235 I--AELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTME-Q 1291 I AE Q L+ + + E +L + +E + + + ++ + E + Sbjct: 617 IKRAESTIQELSSESERLKGSHAEKDNELFSLRDIHETHQRELSTQLRGLEAQLESSEHR 676 Query: 1292 VTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXD 1351 V L L+ EE R + K ++ +++E R++I +++ Sbjct: 677 VLELSESLKAAEEESRTMSTKISETSDELE--RTQIMVQELTADSSKLKEQLAEKESKLF 734 Query: 1352 LRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELT---HQ 1408 L TE S Q+Q + +L+ + R+ D E ++ T Q Sbjct: 735 LLTEKDSKSQVQIK----------ELEATVATLELELESVRARIIDLETEIASKTTVVEQ 784 Query: 1409 LELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKR----IEDLTYEKE---SELAI 1461 LE ++ E+ + E T+ +R E + Q+L + +K+ IE LT E + +EL Sbjct: 785 LEAQNREMVARISELEKTMEERGTELSALTQKLEDNDKQSSSSIETLTAEIDGLRAELDS 844 Query: 1462 LRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNE 1521 + ++ E +E+ ++ +L +E+N + SL+ Q AEL LE++ + +E Sbjct: 845 MSVQKEEVEKQMVCKSEEASVKIKRLDDEVNGLRQQVASLDSQRAELEIQLEKKSEEISE 904 Query: 1522 MQTALENQEIEIVTLNDEITNLQNMVRASSSKIQ 1555 + + N + EI+ ++ + S KI+ Sbjct: 905 YLSQITNLKEEIINKVKVHESILEEINGLSEKIK 938 Score = 119 bits (286), Expect = 8e-25 Identities = 189/1039 (18%), Positives = 438/1039 (42%), Gaps = 61/1039 (5%) Query: 84 RPFVPGISESLANTLKQKEILMEKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQ--L 141 + V ++++L N ++K++L +KI + K + TI L Sbjct: 255 KKLVAELNQTLNNAEEEKKVLSQKIAELSNEIKEAQNTIQELVSESGQLKESHSVKDRDL 314 Query: 142 GDVTHLSNTI-KEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXX 200 + + T +E +S L+ +++ E I DL ++ KD E +NKA + Sbjct: 315 FSLRDIHETHQRESSTRVSELEAQLESSEQRISDLT--VDLKDA--EEENKAISSKNLEI 370 Query: 201 XXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLL 260 ++ ++ ++++ E+E + + + + + EE K+L Sbjct: 371 MDKLEQAQNTIKELMDELGELKDRHKEKESELSSLVKSADQQVADMKQSLDNAEEEKKML 430 Query: 261 EAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIAN 320 +IS E + AQ+ Q + ++ + + E ++ S Sbjct: 431 SQRILDISNEIQE-AQKTIQEHMSESEQLKESHGVKERELT-GLRDIHETHQRESS--TR 486 Query: 321 MTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTAS 380 ++EL +++LLE + + E + ++ + ++ K+ + S Sbjct: 487 LSELETQLKLLEQRVVDLSASLNAAEEEKKSLSSMILEITDELKQAQSKVQELVTELAES 546 Query: 381 K--MKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXX 438 K + ++LSS + K+ + +++ +LE ++S + + + ++ + Sbjct: 547 KDTLTQKENELSSFVEVHEAHKRDSSSQVKELEARVESAEEQVKELNQNLNSSEEEKKIL 606 Query: 439 XXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNV 498 I + + Q+ + S G++ E NE+ +++ E + + Sbjct: 607 SQQISEMSIKIKRAESTIQE-LSSESERLKGSHAEKDNELFSLRDI--HETHQRELSTQL 663 Query: 499 KDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVS-DSNKEI 557 + L +L+S+E ++ +L++ + AA + + + ++++T +++ DS+K Sbjct: 664 RGLEAQLESSEHRVLELSESLKAAEEESRTMSTKISETSDELERTQIMVQELTADSSK-- 721 Query: 558 VRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSG----RMIESDVYKKMIEMENLAETRL 613 L E+L K+ L E+ Q+ + + ++ + V ++I++E ++ Sbjct: 722 --LKEQLAEKESKLFLLTEKDSKSQVQIKELEATVATLELELESVRARIIDLETEIASKT 779 Query: 614 KAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVH-LEEQIDALS 672 + LE+Q ++V + L++ +E +L+ ++Q D S+ L +ID L Sbjct: 780 TVVEQLEAQNREMVARISELEKTMEERGTELSALTQKLEDNDKQSSSSIETLTAEIDGLR 839 Query: 673 ASKKELALVIENLKLD----KEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMS 728 A +++ E ++ E+ IK L+++ + ++ + + +L +LEK S Sbjct: 840 AELDSMSVQKEEVEKQMVCKSEEASVKIKRLDDEVNGLRQQVASLDSQRAELEIQLEKKS 899 Query: 729 AEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVM 788 E+ISE L++I + ++ I K++ + +E I K K R LE Sbjct: 900 -EEISEYLSQITNLKEEIIN-------KVKVHESILEEINGLSEKIKGRELELETLGKQR 951 Query: 789 EDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHEN 848 + L K ++ + +K S + EL+N L +D +V +K E E E Sbjct: 952 SELDEELRTKKEE-NVQMHDKINVASSEIMALTELINNLKNELDSLQV-QKSETEAELE- 1008 Query: 849 KELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLK 908 +E Q+K+++ NQ ++D+Q+ ALVE+ + E E + ++ E+ L Sbjct: 1009 REKQEKSEL---SNQ-----ITDVQK---ALVEQEAAYNTLEEEHKQINELFKETEATLN 1057 Query: 909 RIT---HEHQTLIVQKKKEI--EDLEIEFNTQIESAIRDK-KVLNEKYEKNIEYVTQLEA 962 ++T E Q L+ ++ KE+ D I + + ++R++ ++ ++ E +E ++ +E Sbjct: 1058 KVTVDYKEAQRLLEERGKEVTSRDSTIGVHEETMESLRNELEMKGDEIETLMEKISNIEV 1117 Query: 963 QLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYT---EQYINEINKLNALLK 1019 +L+ + + E + + KH+++Q + T E Y I ++ + Sbjct: 1118 KLRLSNQKLRVTEQVLTEKEEAFRKEEAKHLEEQALLEKNLTMTHETYRGMIKEIADKVN 1177 Query: 1020 QKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNE 1079 + ++++K+ Q Y V + L T + E ++++K++ + + Sbjct: 1178 ITVDGFQSMSEKLTEKQGRYEKTVMEASKILWTATNWVIERNHEKEKMNKEIEKKDEEIK 1237 Query: 1080 ELQILVREQDDQIKELKET 1098 +L VRE + + + +KET Sbjct: 1238 KLGGKVREDEKEKEMMKET 1256 Score = 103 bits (246), Expect = 5e-20 Identities = 188/992 (18%), Positives = 412/992 (41%), Gaps = 85/992 (8%) Query: 141 LGDVTHLSNTIKEKDNALSVL----QVKMKIMETTILDLQEKINEKDQIIEAKNKATTXX 196 + ++ L ++ +EK++ LS L + + + +L+E++ +++ N+ Sbjct: 209 MAELGKLKDSHREKESELSSLVEVHETHQRDSSIHVKELEEQVESSKKLVAELNQTLNNA 268 Query: 197 XXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDE---KQR---LLKDIESKDVRI 250 + K+ +QE ++ + K+ K R L+DI R Sbjct: 269 EEEKKVLSQKIAELSNEIKEAQNTIQE-LVSESGQLKESHSVKDRDLFSLRDIHETHQRE 327 Query: 251 SS--LEEANKLLEAARFEIS--LEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEE 306 SS + E LE++ IS K A+E + A+ +I+ +E Sbjct: 328 SSTRVSELEAQLESSEQRISDLTVDLKDAEEENKAISSKNLEIMDKLEQAQNTIKELMDE 387 Query: 307 KTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKG 366 E++++ + + ++ L K + ++Q+ E + + +S+ ++ Sbjct: 388 LGELKDRHKEKESELSSLVKSAD---QQVADMKQSLDNAEEEKKMLSQRILDISNEIQEA 444 Query: 367 SPLISRKSGRNTASKMKSPWSQLSSETLNQ--DTDKKINKNEIAKLEMVIQSLNKDLVDK 424 I + K + L +T ++ + +++LE ++ L + +VD Sbjct: 445 QKTIQEHMSESEQLKESHGVKERELTGLRDIHETHQRESSTRLSELETQLKLLEQRVVDL 504 Query: 425 EYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQ 484 ++ + + Q Q + Q+ + T T+ NE++ E Sbjct: 505 SASLNAAEEEKKSLSSMILEITDELKQAQSKVQE-LVTELAESKDTLTQKENELSSFVEV 563 Query: 485 LKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAAN---KNMIKVKSNHKLKLKQMQ 541 + D V K+L +++SAEEQ+ +LN ++++ K + + S +K+K+ + Sbjct: 564 HEAHKRDSSSQV--KELEARVESAEEQVKELNQNLNSSEEEKKILSQQISEMSIKIKRAE 621 Query: 542 KTIDNFSKVSDSNK-EIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYK 600 TI S S+ K EL L + + E + + + QL ++ +ES ++ Sbjct: 622 STIQELSSESERLKGSHAEKDNELFSL-RDIHETHQRELSTQLRGLE----AQLESSEHR 676 Query: 601 KMIEMENL--AETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSE 658 + E+L AE + +S S+ D ++ I+ V++ AD S+L+ E Sbjct: 677 VLELSESLKAAEEESRTMSTKISETSDELERTQIM------VQELTADSSKLKEQLAEKE 730 Query: 659 IKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLEND---KEDIMNKLQNYIQ 715 K L E+ KEL + L+L+ E + I DLE + K ++ +L+ + Sbjct: 731 SKLFLLTEKDSKSQVQIKELEATVATLELELESVRARIIDLETEIASKTTVVEQLEAQNR 790 Query: 716 ENMDLTDKLEKMSAEKISELLA---KINHEEQ---SKIQTQF----GIDAKIQERDLYIE 765 E + +LEK E+ +EL A K+ ++ S I+T G+ A++ + E Sbjct: 791 EMVARISELEKTMEERGTELSALTQKLEDNDKQSSSSIETLTAEIDGLRAELDSMSVQKE 850 Query: 766 NIESEL----SKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQ-- 819 +E ++ + +I RL++ + + + SL+ + +L L++K + SEY Q Sbjct: 851 EVEKQMVCKSEEASVKIKRLDDEVNGLRQQVASLDSQRAELEIQLEKKSEEISEYLSQIT 910 Query: 820 --EDELVNRL----AVLMDHDRVVEK---QLLEIE---HENKELQKKNQILLEENQNLQI 867 ++E++N++ ++L + + + EK + LE+E + EL ++ + EEN + Sbjct: 911 NLKEEIINKVKVHESILEEINGLSEKIKGRELELETLGKQRSELDEELRTKKEENVQMHD 970 Query: 868 SLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTL---IVQKKKE 924 ++ AL E N ++E Q Q + E+ L+R E L I +K Sbjct: 971 KINVASSEIMALTELINN---LKNELDSLQVQKSETEAELEREKQEKSELSNQITDVQKA 1027 Query: 925 IEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNK- 983 + + E +NT E + K +NE +++ + ++ +E + +E V + Sbjct: 1028 LVEQEAAYNTLEE----EHKQINELFKETEATLNKVTVDYKEAQRLLEERGKEVTSRDST 1083 Query: 984 --MNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMS 1041 ++ E ++ ++ + D E + +I+ + L+ ++++ Q + + ++ Sbjct: 1084 IGVHEETMES-LRNELEMKGDEIETLMEKISNIEVKLRLSNQKLRVTEQVLTEKEEAFRK 1142 Query: 1042 MVSDYESKLAQFTTKLENMEEEMQRVSKQLLD 1073 + + + A L E + + K++ D Sbjct: 1143 EEAKHLEEQALLEKNLTMTHETYRGMIKEIAD 1174 >UniRef50_A2EUG5 Cluster: Putative uncharacterized protein; n=3; Trichomonas vaginalis G3|Rep: Putative uncharacterized protein - Trichomonas vaginalis G3 Length = 1548 Score = 158 bits (384), Expect = 1e-36 Identities = 254/1300 (19%), Positives = 585/1300 (45%), Gaps = 122/1300 (9%) Query: 312 EKGSLEIANMTELTKKI-ELLEHLNCQIRQT-NKELENKLATMGTESKAVSSPSKKGSPL 369 + ++++ NM E + + + L L+ ++ + +E++ + +G +S S Sbjct: 53 KNSNMQVDNMKEQIQNLTQNLIDLSSKVEKIIPEEIKTAVPNLGQSDYVISVVQHLSSLY 112 Query: 370 ISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQS---LNKDLVDKEY 426 I++ S + T+S ++ S S L + K N A +E + S N+ + + E Sbjct: 113 IAKTSSQYTSSVIQKLNSDNQSIILQNEQLKSENSQLKATIEALHASEMQRNRKIQESER 172 Query: 427 V----ISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQH---MEGPSLIHVG----TNTEDV 475 V + E + + ++I +L E ++ +E G TN ++ Sbjct: 173 VRLEVLRENEAKTKQINNIEAERVSIIRRLTEELKKKDVTIENIKRSKFGKQIPTNIPEI 232 Query: 476 N--EIAKVQEQLK---QELNDEIKDVNVKDLIE--KLKSAEEQITQLNDEIDAANKNMIK 528 + K E +K ++L D +K+ KD+ + ++KS E + QL +E+ KN +K Sbjct: 233 DPQSTVKTDELMKFSVKQLQDLLKEAQTKDIEKDNRIKSYESNLLQLQNEL----KNNMK 288 Query: 529 VKSNHKLKLKQMQKTIDNF-SKVSDSNKEIVR-LTEELH----HLSQKVAELEEEKGNLQ 582 S+ K +++ + I NF +K +++ KE L+ EL L++ + +LEE + LQ Sbjct: 289 TISDLKQVIEEKNRIIYNFETKQTENKKESASSLSNELQATKRRLNEVLKQLEECQKQLQ 348 Query: 583 LHL---VDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHI-LQQKYD 638 + D + S + +K E++NL E+ + LL ++K ++ + LQ+ Sbjct: 349 TQINKPQTIDETNKLRSTIIEKDSEIQNLGES----LHLLSTEKEEIQMKYERKLQKVTT 404 Query: 639 EVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKD 698 ++++ I++ +DQ+ ++K+ + +E I + K+E + + L +K++ +K Sbjct: 405 TLQNEKQKITKQLNDQIL-QLKAQYSQETIKMKNQMKEENLKLTQFLDEEKQKNKNLMKI 463 Query: 699 L-ENDKEDIMNKLQNYIQENMDLTDKLEKMSAEK--ISELLAKINHEEQSKIQTQFGIDA 755 + + +I+++ E++ + K+++MS E+ + + I Q+ T + Sbjct: 464 FNDQNPREIVDEYHYLKDESIAQSQKIKEMSEEREDLQSTILDIQKTLQNTKVTLSQKEI 523 Query: 756 KIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQE-KQKAYS 814 +I + L ++ + S ++ +K + +E +E+R ++ Q+ S + E K K Sbjct: 524 EINDMKLQMQQMTS-VNDFKEVVLEKQELEKTLEERENFIKSLQSQISSQIDECKTKLKD 582 Query: 815 EYTIQEDELVNRLAVLMDHDRVVEKQ---LLEIEHENKELQKKNQILLEENQNLQISLSD 871 + T + L L + + +++ L+++E +N+ L++K ++ LEEN L Sbjct: 583 QNTKLVENLAQINTKLEERETKLQRLQSCLIDVEKQNQNLKEKLRVSLEENVKL------ 636 Query: 872 MQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTL--IVQKKKEIEDLE 929 + +EK N+ + E+T + +E N I HQT+ + ++K+ + L Sbjct: 637 -----GSEIEKLNK----QMENTNIE-----IEVNNDAILDLHQTIDKLTKEKENLTKLN 682 Query: 930 IEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELI 989 E + E + K + +KY+K ++Q E QL E ++ IE + E+ +++N LI Sbjct: 683 DENLAEKEKMKKSLKKMEKKYDKLQSSISQKEMQLSELQDTIEKVK--TEKSSQIN-SLI 739 Query: 990 DKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESK 1049 K V++++ Q + TE + ++ +++Q + LN+ N + VS E Sbjct: 740 KK-VEEKENQIRE-TENTLKDMQMSQTVIEQNHQNEKQLNE---NKIKEFEKKVSKLEKI 794 Query: 1050 LAQFTTKLENMEEEMQRVSKQLLDSKQ-HNEELQILVREQDDQIKELKETKLTFEMNIPK 1108 + + + N++ E ++ + + KQ ++Q + Q++ K KE++LT EM Sbjct: 795 VFKLKDYINNLQIEKEKYENKFKELKQIAKNQMQTSLDFQNESEKN-KESRLTSEMAF-- 851 Query: 1109 TEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTEL 1168 +S + N + L+ Q E+ +Q +Q ++K+ + Sbjct: 852 ---QTLSKKYNDLQSKYNERNNAIDTLSKDLELLRNQVSEKNVQ----IQTLNSKIENQ- 903 Query: 1169 QECYTKIIQLET-LNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSA 1227 E +I++L+ L T + +D NQ+++ + K+K+ + +++ L + + Sbjct: 904 DEMKHEILKLQNKLQTFIESNDK-NQKELEETKNKVNEEKEKSEKLKLETESKENDLIQK 962 Query: 1228 VDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIV 1287 +++ IA L +Q +F K EL + K + L ++ ++++ K V Sbjct: 963 INELNLTIASLTEQ-TKNPPVEFTKKMTELEL----INKKVTEDLTKIKEESEKQ--KRV 1015 Query: 1288 TMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXX 1347 + L++ D ++ + D+ N +++ + E++ A Sbjct: 1016 LKRENDELKSINADYKKQI-------IDLSNDVDLNGTNFENKLSAKVREIQDLKMKNEN 1068 Query: 1348 XXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTH 1407 L +Y++ Q++ +++ N +++ ++++ K+L Sbjct: 1069 LMKTLEDLKLNYQE-QKEKLVSENASLTSKLETNQNNLNSLTTKEKQISEENKKLLTENG 1127 Query: 1408 QLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYE----KRIEDLTYE-KESELAIL 1462 +++ K + + ++ E L++ + F+N+ + EY+ K+I+ L ++ + ++ I+ Sbjct: 1128 EIKNKITVLTKQNEELNDNLSKSKESFDNLNNEYQEYKRTNNKQIDGLNHQINDQKVDIM 1187 Query: 1463 RLK--MHENANHYETMQKE-SEIERVKLIEELNVKITESVSLNKQVAE--LNKALEEEVA 1517 L + + N + M++ ++ +K E+LN K +L ++ + L+ A+++ Sbjct: 1188 NLSKVIEKKQNKIQEMKEVINQSVNIKDFEKLNKKYLAVKNLYEKSEKKVLSTAIDQGTI 1247 Query: 1518 KTNEMQ---TALENQEIEIVTLNDEITNLQNMVRASSSKI 1554 + +M + +E Q+ EI L D+I N ++ +R +I Sbjct: 1248 REQQMSEFLSKIETQQKEIDDLKDKIQNKEDFIRKLQRQI 1287 Score = 144 bits (348), Expect = 2e-32 Identities = 255/1198 (21%), Positives = 526/1198 (43%), Gaps = 132/1198 (11%) Query: 90 ISESLANTLKQKEILMEKIKQYKELSKRSSTTIVRX---XXXXXXXXXXXXXXQLGDVT- 145 I L LK+K++ +E IK+ K K+ T I QL D+ Sbjct: 198 IIRRLTEELKKKDVTIENIKRSK-FGKQIPTNIPEIDPQSTVKTDELMKFSVKQLQDLLK 256 Query: 146 -------HLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQII-EAKNKATTXXX 197 N IK ++ L LQ ++K TI DL++ I EK++II + K T Sbjct: 257 EAQTKDIEKDNRIKSYESNLLQLQNELKNNMKTISDLKQVIEEKNRIIYNFETKQTENKK 316 Query: 198 XXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWK-----DEKQRLLKDIESKDVRISS 252 + + +++E ++ + DE +L I KD I + Sbjct: 317 ESASSLSNELQATKRRLNEVLKQLEECQKQLQTQINKPQTIDETNKLRSTIIEKDSEIQN 376 Query: 253 LEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTE-IE 311 L E+ LL + EI +++ + Q++ L Q ++ + E I+ Sbjct: 377 LGESLHLLSTEKEEIQMKYERKLQKV--TTTLQNEKQKITKQLNDQILQLKAQYSQETIK 434 Query: 312 EKGSLEIANMTELTKKIELLEHLNCQIR-----QTNKELENKLATMGTESKAVSSPSKKG 366 K ++ N+ +LT+ ++ + N + Q +E+ ++ + ES A S K+ Sbjct: 435 MKNQMKEENL-KLTQFLDEEKQKNKNLMKIFNDQNPREIVDEYHYLKDESIAQSQKIKEM 493 Query: 367 SPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEY 426 S R+ ++T ++ Q + TL+Q K+I N++ KL+M + D KE Sbjct: 494 SE--EREDLQSTILDIQKT-LQNTKVTLSQ---KEIEINDM-KLQMQQMTSVNDF--KEV 544 Query: 427 VISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLK 486 V+ +++ ++ I LQ + ++ NT+ V +A++ +L+ Sbjct: 545 VLEKQELEKTLEE-----RENFIKSLQSQISSQIDECKTKLKDQNTKLVENLAQINTKLE 599 Query: 487 ------QELNDEIKDVNV--KDLIEKLKSAEEQITQLNDEIDAANKNM----IKVKSNHK 534 Q L + DV ++L EKL+ + E+ +L EI+ NK M I+++ N+ Sbjct: 600 ERETKLQRLQSCLIDVEKQNQNLKEKLRVSLEENVKLGSEIEKLNKQMENTNIEIEVNND 659 Query: 535 LKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMI 594 L + +TID K++ + + +L +E +AE E+ K +L+ YD + Sbjct: 660 AIL-DLHQTID---KLTKEKENLTKLNDE------NLAEKEKMKKSLKKMEKKYDK---L 706 Query: 595 ESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLAD--ISQL-- 650 +S + +K +++ L +T K + SQ L++++ + + E E+ L D +SQ Sbjct: 707 QSSISQKEMQLSELQDTIEKVKTEKSSQINSLIKKVEEKENQIRETENTLKDMQMSQTVI 766 Query: 651 ----QSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDI 706 Q+++ +E K E+++ L +L I NL+++KE+ K+L K+ Sbjct: 767 EQNHQNEKQLNENKIKEFEKKVSKLEKIVFKLKDYINNLQIEKEKYENKFKEL---KQIA 823 Query: 707 MNKLQNYIQ-ENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIE 765 N++Q + +N +K ++++E + L+K ++ QSK + + I +E Sbjct: 824 KNQMQTSLDFQNESEKNKESRLTSEMAFQTLSKKYNDLQSKYNER---NNAIDTLSKDLE 880 Query: 766 NIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVN 825 + +++S+ +I L I ++ ++ + + ++L ++++ K E +E N Sbjct: 881 LLRNQVSEKNVQIQTLNSKIENQDEMKHEILKLQNKLQTFIESNDKNQKEL----EETKN 936 Query: 826 RLAVLMDHDRVVEKQLLEIE-HENKELQKKNQI------LLEENQNLQISLSDMQQHYNA 878 + + + EK LE E EN +QK N++ L E+ +N + + Sbjct: 937 K---VNEEKEKSEKLKLETESKENDLIQKINELNLTIASLTEQTKNPPVEFTKKMTELE- 992 Query: 879 LVEKANRTDLA--ESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQI 936 L+ K DL + ES K + L+ LK I +++ I+ +++ F ++ Sbjct: 993 LINKKVTEDLTKIKEESEKQKRVLKRENDELKSINADYKKQIIDLSNDVDLNGTNFENKL 1052 Query: 937 ESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNI--ENLNMNVE-ELNKMNL-ELIDKH 992 + +R+ + L K E ++ + L+ QE K + EN ++ + E N+ NL L K Sbjct: 1053 SAKVREIQDLKMKNENLMKTLEDLKLNYQEQKEKLVSENASLTSKLETNQNNLNSLTTKE 1112 Query: 993 VQKQQTQSPDYTEQYINEI-NKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLA 1051 Q + TE EI NK+ L KQ +E LN ++ ++ S+ ++ ++Y+ Sbjct: 1113 KQISEENKKLLTEN--GEIKNKITVLTKQNEE----LNDNLSKSKESFDNLNNEYQEYKR 1166 Query: 1052 QFTTKLENMEEEM--QRVS----KQLLDSKQHN-EELQILVREQDD--QIKELKETKLTF 1102 +++ + ++ Q+V ++++ KQ+ +E++ ++ + + ++L + L Sbjct: 1167 TNNKQIDGLNHQINDQKVDIMNLSKVIEKKQNKIQEMKEVINQSVNIKDFEKLNKKYLAV 1226 Query: 1103 EMNIPKTEGMIISSTI-------EPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQE-R 1154 + K+E ++S+ I + MS+ + ++ K+Q +E+FI++ + Sbjct: 1227 KNLYEKSEKKVLSTAIDQGTIREQQMSEFLSKIETQQKEIDDLKD--KIQNKEDFIRKLQ 1284 Query: 1155 SVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDN 1212 + KL + + +I+L L E+ ++Q+N+ +K++ L + N Sbjct: 1285 RQIATDGQKLEEITSQPFVPLIELTNLRQEMR----EKEKQLNESLAKIKFLEEKKAN 1338 Score = 136 bits (329), Expect = 5e-30 Identities = 200/1050 (19%), Positives = 474/1050 (45%), Gaps = 88/1050 (8%) Query: 306 EKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKK 365 ++TE +++ + ++N + TK+ LN ++Q +E + +L T + + + +K Sbjct: 310 KQTENKKESASSLSNELQATKR-----RLNEVLKQL-EECQKQLQTQINKPQTIDETNKL 363 Query: 366 GSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKE 425 S +I + S + S E + ++K+ K L+ Q + K L D+ Sbjct: 364 RSTIIEKDSEIQNLGESLHLLST-EKEEIQMKYERKLQK-VTTTLQNEKQKITKQLNDQI 421 Query: 426 YVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQL 485 + + + ++ L Q ++ + +L+ + N ++ EI L Sbjct: 422 LQLKAQYSQETIKMKNQMKEENL-KLTQFLDEEKQKNKNLMKI-FNDQNPREIVDEYHYL 479 Query: 486 KQE-LNDEIKDVNVKDLIEKLKSA--EEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQK 542 K E + K + + E L+S + Q T N ++ + K I++ ++ KL+++QM Sbjct: 480 KDESIAQSQKIKEMSEEREDLQSTILDIQKTLQNTKVTLSQKE-IEI-NDMKLQMQQMT- 536 Query: 543 TIDNFSKVSDSNKEIVRLTEELHHLSQKV-AELEEEKGNLQLHLVDYDSGRMIES--DVY 599 ++++F +V +E+ + EE + + + +++ + + L D ++ +++E+ + Sbjct: 537 SVNDFKEVVLEKQELEKTLEERENFIKSLQSQISSQIDECKTKLKDQNT-KLVENLAQIN 595 Query: 600 KKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADIS-QLQSDQVCSE 658 K+ E E + + +E Q +L ++L + ++ ++ ++ ++ Q+++ + E Sbjct: 596 TKLEERETKLQRLQSCLIDVEKQNQNLKEKLRVSLEENVKLGSEIEKLNKQMENTNIEIE 655 Query: 659 IKS---VHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQ 715 + + + L + ID L+ K+ L + + +KE++ ++K +E + + + + Sbjct: 656 VNNDAILDLHQTIDKLTKEKENLTKLNDENLAEKEKMKKSLKKMEKKYDKLQSSISQKEM 715 Query: 716 ENMDLTDKLEKMSAEK---ISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELS 772 + +L D +EK+ EK I+ L+ K+ +E +T+ + + + +N ++E Sbjct: 716 QLSELQDTIEKVKTEKSSQINSLIKKVEEKENQIRETENTLKDMQMSQTVIEQNHQNEKQ 775 Query: 773 KYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMD 832 +++I E+ ++ +E + L+ D + + EK+K +++ + N++ +D Sbjct: 776 LNENKIKEFEKKVSKLEKIVFKLK---DYINNLQIEKEKYENKFKELKQIAKNQMQTSLD 832 Query: 833 HDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHY----NALVEKANRTDL 888 EK NKE + +++ Q L +D+Q Y NA+ + +L Sbjct: 833 FQNESEK--------NKESRLTSEMAF---QTLSKKYNDLQSKYNERNNAIDTLSKDLEL 881 Query: 889 AESESTKYQTQLRDLESNLKRITH-EHQTLIVQKKKEIEDLEIEFNTQIESAIRD-KKVL 946 ++ ++ Q++ L S ++ +H+ L +Q K + IE N + + + + K + Sbjct: 882 LRNQVSEKNVQIQTLNSKIENQDEMKHEILKLQNKLQ---TFIESNDKNQKELEETKNKV 938 Query: 947 NEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQ 1006 NE+ EK+ + + E++ + I LN+ + L + + K+ T+ ++ Sbjct: 939 NEEKEKSEKLKLETESKENDLIQKINELNLTIASLTEQT-KNPPVEFTKKMTELELINKK 997 Query: 1007 YINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQR 1066 ++ K+ +++ + N ++ + Y + D + + T N E ++ Sbjct: 998 VTEDLTKIKEESEKQKRVLKRENDELKSINADYKKQIIDLSNDVDLNGT---NFENKLSA 1054 Query: 1067 VSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPK--TEGMIISSTIEPMSDD 1124 +++ D K NE L +K L++ KL ++ K +E ++S +E ++ Sbjct: 1055 KVREIQDLKMKNENL----------MKTLEDLKLNYQEQKEKLVSENASLTSKLETNQNN 1104 Query: 1125 ANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTE 1184 N++ L + E E + +VL +Q+ +LN L + + LN E Sbjct: 1105 LNSLTTKEKQISEENKKL-LTENGEIKNKITVLTKQNEELNDNLSKSKE---SFDNLNNE 1160 Query: 1185 LTGHDVVNQEQINQLKSKLEQLNTENDNL-------LSTVAELRSSISSAVDQRGFEIAE 1237 + N +QI+ L ++ + NL + + E++ I+ +V+ + FE + Sbjct: 1161 YQEYKRTNNKQIDGLNHQINDQKVDIMNLSKVIEKKQNKIQEMKEVINQSVNIKDFE--K 1218 Query: 1238 LWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTME-QVTSLQ 1296 L K++LA + ++K+E +V +A + + + Q S E +KI T + ++ L+ Sbjct: 1219 LNKKYLAVKNL-YEKSEK--KVLSTAID---QGTIREQQMS--EFLSKIETQQKEIDDLK 1270 Query: 1297 NKLQDKEEHLRNLQEKYADVINQIEILRSE 1326 +K+Q+KE+ +R LQ + A ++E + S+ Sbjct: 1271 DKIQNKEDFIRKLQRQIATDGQKLEEITSQ 1300 Score = 135 bits (327), Expect = 8e-30 Identities = 230/1158 (19%), Positives = 509/1158 (43%), Gaps = 122/1158 (10%) Query: 477 EIAKVQEQLKQELNDEIKDVN--VKDLI-EKLKSAEEQITQLNDEIDAANKNMIKVKSNH 533 ++ ++EQ+ Q L + D++ V+ +I E++K+A + Q + I ++++ S+ Sbjct: 58 QVDNMKEQI-QNLTQNLIDLSSKVEKIIPEEIKTAVPNLGQSDYVI-----SVVQHLSSL 111 Query: 534 KLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQ-LHLVDYDSGR 592 + Q T K++ N+ I+ E+L +E + K ++ LH + R Sbjct: 112 YIAKTSSQYTSSVIQKLNSDNQSIILQNEQLK------SENSQLKATIEALHASEMQRNR 165 Query: 593 MI-ESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQ 651 I ES+ + + EN A+T K I+ +E+++ +++ L +E++ K I ++ Sbjct: 166 KIQESERVRLEVLRENEAKT--KQINNIEAERVSIIRRLT------EELKKKDVTIENIK 217 Query: 652 SDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQ 711 + +I + ++ E ID S K + E +K +QL +K+ + + N+++ Sbjct: 218 RSKFGKQIPT-NIPE-IDPQSTVKTD-----ELMKFSVKQLQDLLKEAQTKDIEKDNRIK 270 Query: 712 NYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESEL 771 +Y + L ++L K + + IS+L I EE+++I F +++ ++ +EL Sbjct: 271 SYESNLLQLQNEL-KNNMKTISDLKQVI--EEKNRIIYNFETKQTENKKES-ASSLSNEL 326 Query: 772 SKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLM 831 K R L E + +E+ + L+ + ++ + + E K S I++D + L + Sbjct: 327 QATKRR---LNEVLKQLEECQKQLQTQINKPQT-IDETNKLRSTI-IEKDSEIQNLGESL 381 Query: 832 DHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDM-----QQHYNALVEKANRT 886 H EK+ +++++E K LQK L E Q + L+D Q+ ++ N+ Sbjct: 382 -HLLSTEKEEIQMKYERK-LQKVTTTLQNEKQKITKQLNDQILQLKAQYSQETIKMKNQM 439 Query: 887 DLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVL 946 + T++ + + NL +I ++ Q +EI D E++ + +I + + Sbjct: 440 KEENLKLTQFLDEEKQKNKNLMKIFND------QNPREIVD---EYHYLKDESIAQSQKI 490 Query: 947 NEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQ 1006 E E+ + L++ + + + ++N + L++ +E+ D +Q QQ S + ++ Sbjct: 491 KEMSEERED----LQSTILDIQKTLQNTKVT---LSQKEIEINDMKLQMQQMTSVNDFKE 543 Query: 1007 YINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKL----AQFTTKLENMEE 1062 + E +L L++++ I +L +I++ + + D +KL AQ TKLE E Sbjct: 544 VVLEKQELEKTLEERENFIKSLQSQISSQIDECKTKLKDQNTKLVENLAQINTKLEERET 603 Query: 1063 EMQRVSKQLLDSKQHNEELQILVREQ-DDQIKELKET-KLTFEMNIPKTEGMIISSTIEP 1120 ++QR+ L+D ++ N+ L+ +R ++ +K E KL +M E + + I Sbjct: 604 KLQRLQSCLIDVEKQNQNLKEKLRVSLEENVKLGSEIEKLNKQMENTNIEIEVNNDAILD 663 Query: 1121 MSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLET 1180 + + + + E+E+ + ++++ KL + + + K +QL Sbjct: 664 LHQTIDKLTKEKENLTKLNDE-NLAEKEKMKKSLKKMEKKYDKLQSSISQ---KEMQLSE 719 Query: 1181 LNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWK 1240 L + QIN L K+E+ + +T+ +++ S + ++Q +L + Sbjct: 720 LQDTIEKVKTEKSSQINSLIKKVEEKENQIRETENTLKDMQMS-QTVIEQNHQNEKQLNE 778 Query: 1241 QHLAQREADFQKTE----------HELRVQLSAFESKYEQLL----DSVQSSTQEETNKI 1286 + + E K E + L+++ +E+K+++L + +Q+S + Sbjct: 779 NKIKEFEKKVSKLEKIVFKLKDYINNLQIEKEKYENKFKELKQIAKNQMQTSLDFQNESE 838 Query: 1287 VTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQI-------EILRSEIEDEKVAFXXXXX 1339 E + + Q + +LQ KY + N I E+LR+++ ++ V Sbjct: 839 KNKESRLTSEMAFQTLSKKYNDLQSKYNERNNAIDTLSKDLELLRNQVSEKNVQIQTLNS 898 Query: 1340 XXXXXXXXXXXDLRTENQ----------SYKQMQEQSILNINEENAQLKKSSXXXXXXXX 1389 L+ +N+ + K+++E +NEE + +K Sbjct: 899 KIENQDEMKHEILKLQNKLQTFIESNDKNQKELEETKN-KVNEEKEKSEKLKLETESKEN 957 Query: 1390 XXXXRVNDAEAKVLELTHQLELKDSEIYQKTHE-------YTITLTQRNDEFENVRQQLV 1442 ++N+ + LT Q + E +K E T LT+ +E E ++ L Sbjct: 958 DLIQKINELNLTIASLTEQTKNPPVEFTKKMTELELINKKVTEDLTKIKEESEKQKRVLK 1017 Query: 1443 EYEKRIEDLTYEKESELAILRLKMHENANHYET--MQKESEIERVKLIEELNVKITESVS 1500 ++ + + + ++ L + N ++E K EI+ +K+ E +K E + Sbjct: 1018 RENDELKSINADYKKQIIDLSNDVDLNGTNFENKLSAKVREIQDLKMKNENLMKTLEDLK 1077 Query: 1501 LNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSF 1560 LN Q + K + E + T++++T +N + T +I+ + + +I+ ++ Sbjct: 1078 LNYQ-EQKEKLVSENASLTSKLETN-QNNLNSLTTKEKQISEENKKLLTENGEIKNKITV 1135 Query: 1561 ASDTKQGRDEQLDNTMNK 1578 TKQ +E+L++ ++K Sbjct: 1136 L--TKQ--NEELNDNLSK 1149 Score = 135 bits (326), Expect = 1e-29 Identities = 236/1122 (21%), Positives = 504/1122 (44%), Gaps = 152/1122 (13%) Query: 228 MEAEWKDEKQRLLKDIESKDVRISSLEEA--NKLLEAARFEISLEHSKLAQELEQXXXXX 285 +EAE +RL ++++ KDV I +++ + K + EI + + EL + Sbjct: 191 IEAERVSIIRRLTEELKKKDVTIENIKRSKFGKQIPTNIPEIDPQSTVKTDELMK----- 245 Query: 286 XXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKEL 345 L K++ E+ I+ S + EL ++ + L I + N+ + Sbjct: 246 -FSVKQLQDLLKEAQTKDIEKDNRIKSYESNLLQLQNELKNNMKTISDLKQVIEEKNRII 304 Query: 346 ENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINK- 404 N T TE+K S+ S +++ +++ QL ++ T + NK Sbjct: 305 YN-FETKQTENKKESASSLSNELQATKRRLNEVLKQLEECQKQLQTQINKPQTIDETNKL 363 Query: 405 -NEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGP 463 + I + + IQ+L + L + +EK+ ++Q+++++ ++ Sbjct: 364 RSTIIEKDSEIQNLGESL---HLLSTEKE------------------EIQMKYERKLQ-- 400 Query: 464 SLIHVGTNTEDVNEIAKVQEQLKQ---ELNDEIKDVNVKDLIEKLKSAEEQITQLNDEID 520 V T + NE K+ +QL +L + +K + ++K ++TQ DE Sbjct: 401 ---KVTTTLQ--NEKQKITKQLNDQILQLKAQYSQETIK-MKNQMKEENLKLTQFLDEEK 454 Query: 521 AANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGN 580 NKN++K+ ++ + ++ +D + + D + I + SQK+ E+ EE+ + Sbjct: 455 QKNKNLMKIFND-----QNPREIVDEYHYLKD--ESIAQ--------SQKIKEMSEERED 499 Query: 581 LQLHLVDYDSG-RMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDE 639 LQ ++D + + + +K IE+ ++ + +++ ++ + K ++V E L++ +E Sbjct: 500 LQSTILDIQKTLQNTKVTLSQKEIEINDM-KLQMQQMTSVNDFK-EVVLEKQELEKTLEE 557 Query: 640 VEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDL 699 E+ + + S Q+ E K+ L++Q L + ++ +E + ++L + D+ Sbjct: 558 RENFIKSLQSQISSQI-DECKT-KLKDQNTKLVENLAQINTKLEERETKLQRLQSCLIDV 615 Query: 700 ENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQE 759 E +++ KL+ ++EN+ L ++EK++ + E + I+ + DA + Sbjct: 616 EKQNQNLKEKLRVSLEENVKLGSEIEKLNKQM-----------ENTNIEIEVNNDAIL-- 662 Query: 760 RDLYIENIESELSKYKSRICRL-EESIAVMEDRRYSL---ERKADQLGSYLQEKQKAYSE 815 DL+ + I+ +L+K K + +L +E++A E + SL E+K D+L S + +K+ SE Sbjct: 663 -DLH-QTID-KLTKEKENLTKLNDENLAEKEKMKKSLKKMEKKYDKLQSSISQKEMQLSE 719 Query: 816 Y--TIQ--EDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSD 871 TI+ + E +++ L+ E Q+ E E+ K++Q ++ + +QN + + Sbjct: 720 LQDTIEKVKTEKSSQINSLIKKVEEKENQIRETENTLKDMQMSQTVIEQNHQNEKQLNEN 779 Query: 872 MQQHYNALVEKANR--------TDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKK 923 + + V K + + + E KY+ + ++L+ K ++ QT + + + Sbjct: 780 KIKEFEKKVSKLEKIVFKLKDYINNLQIEKEKYENKFKELKQIAK---NQMQTSLDFQNE 836 Query: 924 EIEDLEIEFNTQIESAIRDKKV--LNEKY-EKN--IEYVTQ----LEAQLQEYKNNIENL 974 ++ E +++ KK L KY E+N I+ +++ L Q+ E I+ L Sbjct: 837 SEKNKESRLTSEMAFQTLSKKYNDLQSKYNERNNAIDTLSKDLELLRNQVSEKNVQIQTL 896 Query: 975 NMNVEELNKMNLELIDKHVQKQQT--QSPDYTEQYINEI-NKLNALLKQKDEEIIA---- 1027 N +E ++M E++ K K QT +S D ++ + E NK+N K+K E++ Sbjct: 897 NSKIENQDEMKHEIL-KLQNKLQTFIESNDKNQKELEETKNKVNE-EKEKSEKLKLETES 954 Query: 1028 ----LNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQI 1083 L QKIN ++ S+ ++ +FT K+ +E ++V++ L K+ +E+ + Sbjct: 955 KENDLIQKINELNLTIASLTEQTKNPPVEFTKKMTELELINKKVTEDLTKIKEESEKQKR 1014 Query: 1084 LVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLK 1143 +++ ++D ELK ++ I D +N+VD K Sbjct: 1015 VLKREND---ELKSINADYKKQI---------------IDLSNDVDLNGTNFENKLSA-K 1055 Query: 1144 VQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKL 1203 V+E ++ + L + L QE K++ + N LT NQ +N L +K Sbjct: 1056 VREIQDLKMKNENLMKTLEDLKLNYQEQKEKLV---SENASLTSKLETNQNNLNSLTTKE 1112 Query: 1204 EQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSA 1263 +Q++ EN LL+ E+++ I+ Q E +L++ + F +E + Sbjct: 1113 KQISEENKKLLTENGEIKNKITVLTKQN-----EELNDNLSKSKESFDNLNNEYQ----E 1163 Query: 1264 FESKYEQLLDSVQSSTQEETNKIVTMEQV-TSLQNKLQDKEE 1304 ++ + +D + ++ I+ + +V QNK+Q+ +E Sbjct: 1164 YKRTNNKQIDGLNHQINDQKVDIMNLSKVIEKKQNKIQEMKE 1205 Score = 125 bits (302), Expect = 9e-27 Identities = 184/917 (20%), Positives = 377/917 (41%), Gaps = 80/917 (8%) Query: 669 DALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMS 728 D++S S N L+ E L IK+ +++ ++QN Q +DL+ K+EK+ Sbjct: 28 DSVSLSSIHETKNKRNQVLEYEML---IKNSNMQVDNMKEQIQNLTQNLIDLSSKVEKII 84 Query: 729 AEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVM 788 E+I + + Q+ + I LYI S+ + + + ++ Sbjct: 85 PEEIKTAVPNLG-------QSDYVISVVQHLSSLYIAKTSSQYTSSVIQKLNSDNQSIIL 137 Query: 789 EDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHEN 848 ++ + E + + IQE E V RL VL +++ KQ+ IE E Sbjct: 138 QNEQLKSENSQLKATIEALHASEMQRNRKIQESERV-RLEVLRENEAKT-KQINNIEAER 195 Query: 849 KELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLK 908 + ++ L EE + +++ ++++ N ++ + K ++ L+ Sbjct: 196 VSIIRR---LTEELKKKDVTIENIKRSKFGKQIPTNIPEIDPQSTVKTDELMKFSVKQLQ 252 Query: 909 RITHEHQTLIVQKKKEIEDLE---IEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQ 965 + E QT ++K I+ E ++ ++++ ++ L + E+ + E + Sbjct: 253 DLLKEAQTKDIEKDNRIKSYESNLLQLQNELKNNMKTISDLKQVIEEKNRIIYNFETKQT 312 Query: 966 EYKNNIENLNMNVEELNKMNLELIDKHVQK--QQTQSPDYTEQYINEINKLNALLKQKDE 1023 E K + N + K L + K +++ +Q Q+ Q I+E NKL + + +KD Sbjct: 313 ENKKESASSLSNELQATKRRLNEVLKQLEECQKQLQTQINKPQTIDETNKLRSTIIEKDS 372 Query: 1024 EIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQI 1083 EI L + ++ + YE KL + TT L+N E Q+++KQL D + LQ+ Sbjct: 373 EIQNLGESLHLLSTEKEEIQMKYERKLQKVTTTLQN---EKQKITKQLND-----QILQL 424 Query: 1084 LVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLK 1143 + + IK + K E N+ T+ + D+ + + Sbjct: 425 KAQYSQETIKMKNQMK---EENLKLTQFL----------DEEKQKNKNLMKIFNDQNPRE 471 Query: 1144 VQEEEEFIQERSVLQEQSAK-LNTELQECYTKIIQLE-TL-NTELTGHDVVNQEQINQLK 1200 + +E ++++ S+ Q Q K ++ E ++ + I+ ++ TL NT++T + +IN +K Sbjct: 472 IVDEYHYLKDESIAQSQKIKEMSEEREDLQSTILDIQKTLQNTKVTLSQ--KEIEINDMK 529 Query: 1201 SKLEQLNTEND---------NLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQ 1251 +++Q+ + ND L T+ E + I S Q +I E K L + Sbjct: 530 LQMQQMTSVNDFKEVVLEKQELEKTLEERENFIKSLQSQISSQIDEC-KTKLKDQNTKLV 588 Query: 1252 KTEHELRVQLSAFESKYEQL---LDSVQSSTQEETNKI-VTMEQVTSLQNKLQDKEEHLR 1307 + ++ +L E+K ++L L V+ Q K+ V++E+ L ++++ + + Sbjct: 589 ENLAQINTKLEERETKLQRLQSCLIDVEKQNQNLKEKLRVSLEENVKLGSEIEKLNKQME 648 Query: 1308 NLQ---EKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQE 1364 N E D I + ++ EK L+ + Y ++Q Sbjct: 649 NTNIEIEVNNDAILDLHQTIDKLTKEKENLTKLNDENLAEKEKMKKSLKKMEKKYDKLQS 708 Query: 1365 QSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYT 1424 +I+++ QL + ++N KV E +Q+ ++ + T Sbjct: 709 ----SISQKEMQLSELQDTIEKVKTEKSSQINSLIKKVEEKENQIRETENTLKDMQMSQT 764 Query: 1425 ITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIER 1484 + +E + ++ E+EK++ L E + +LK + N E + E++ + Sbjct: 765 VIEQNHQNEKQLNENKIKEFEKKVSKL------EKIVFKLKDYINNLQIEKEKYENKFKE 818 Query: 1485 VKLIEELNVKITESVSLNKQVAELNKALEEEVA------KTNEMQTALENQEIEIVTLND 1538 +K I + N T N+ L E+A K N++Q+ + I TL+ Sbjct: 819 LKQIAK-NQMQTSLDFQNESEKNKESRLTSEMAFQTLSKKYNDLQSKYNERNNAIDTLSK 877 Query: 1539 EITNLQNMVRASSSKIQ 1555 ++ L+N V + +IQ Sbjct: 878 DLELLRNQVSEKNVQIQ 894 Score = 110 bits (265), Expect = 3e-22 Identities = 179/872 (20%), Positives = 387/872 (44%), Gaps = 85/872 (9%) Query: 235 EKQRLLKDIESKDVRISSLE-EANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXX 293 EKQ L K +E ++ I SL+ + + ++ + ++ +++KL + L Q Sbjct: 547 EKQELEKTLEERENFIKSLQSQISSQIDECKTKLKDQNTKLVENLAQINTKLEERETKLQ 606 Query: 294 XLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMG 353 L I+ ++ ++EK + + +L +IE LN Q+ TN E+E Sbjct: 607 RLQSCLIDVE-KQNQNLKEKLRVSLEENVKLGSEIE---KLNKQMENTNIEIE------- 655 Query: 354 TESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMV 413 ++ + +K K ++L+ E L +K+ K + K+E Sbjct: 656 ----------VNNDAILDLHQTIDKLTKEKENLTKLNDENL---AEKEKMKKSLKKMEKK 702 Query: 414 IQSLNKDLVDKEYVISE-KDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNT 472 L + KE +SE +DT ++LI +++ + Q E + + Sbjct: 703 YDKLQSSISQKEMQLSELQDTIEKVKTEKSSQINSLIKKVEEKENQIRETENTL------ 756 Query: 473 EDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSN 532 +D+ V EQ Q ++ + +K+ +K+ E+ + +L D I+ N + K K Sbjct: 757 KDMQMSQTVIEQNHQN-EKQLNENKIKEFEKKVSKLEKIVFKLKDYIN--NLQIEKEKYE 813 Query: 533 HKLK-LKQMQK----TIDNFSKVSDSNKEIVRLTEEL--HHLSQKVAELEEEKGNLQLHL 585 +K K LKQ+ K T +F S+ NKE RLT E+ LS+K +L+ K N + + Sbjct: 814 NKFKELKQIAKNQMQTSLDFQNESEKNKES-RLTSEMAFQTLSKKYNDLQS-KYNERNNA 871 Query: 586 VDYDSG--RMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDK 643 +D S ++ + V +K ++++ L ++++ ++ + L +L + D+ + + Sbjct: 872 IDTLSKDLELLRNQVSEKNVQIQTL-NSKIENQDEMKHEILKLQNKLQTFIESNDKNQKE 930 Query: 644 LADI-SQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLEND 702 L + +++ ++ SE + E + + L EL L I +L + +N Sbjct: 931 LEETKNKVNEEKEKSEKLKLETESKENDLIQKINELNLTIASLT----------EQTKNP 980 Query: 703 KEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDL 762 + K+ N +T+ L K+ E SE ++ E ++++ D K Q DL Sbjct: 981 PVEFTKKMTELELINKKVTEDLTKIKEE--SEKQKRVLKRENDELKS-INADYKKQIIDL 1037 Query: 763 YIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLG-SYLQEKQKAYSEYTIQED 821 +++ + +++++ I ++ + +L + + L +Y ++K+K SE Sbjct: 1038 S-NDVDLNGTNFENKLSAKVREIQDLKMKNENLMKTLEDLKLNYQEQKEKLVSENASLTS 1096 Query: 822 ELV---NRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNA 878 +L N L L ++ + ++ ++ EN E++ K +L ++N+ L +LS ++ ++ Sbjct: 1097 KLETNQNNLNSLTTKEKQISEENKKLLTENGEIKNKITVLTKQNEELNDNLSKSKESFDN 1156 Query: 879 L---VEKANRTDLAESESTKYQTQLRDLE-SNLKRITHEHQTLIVQKKKEI-EDLEIEFN 933 L ++ RT+ + + +Q + ++ NL ++ + Q I + K+ I + + I+ Sbjct: 1157 LNNEYQEYKRTNNKQIDGLNHQINDQKVDIMNLSKVIEKKQNKIQEMKEVINQSVNIKDF 1216 Query: 934 TQIESAIRDKKVLNEKYEKN-----IEYVTQLEAQLQEYKNNIENLNMNVEELNK--MNL 986 ++ K L EK EK I+ T E Q+ E+ + IE +++L N Sbjct: 1217 EKLNKKYLAVKNLYEKSEKKVLSTAIDQGTIREQQMSEFLSKIETQQKEIDDLKDKIQNK 1276 Query: 987 ELIDKHVQKQQTQSPDYTEQYIN-------EINKLNALLKQKDEEIIALNQKINNAQVSY 1039 E + +Q+Q E+ + E+ L +++K++++ KI + Sbjct: 1277 EDFIRKLQRQIATDGQKLEEITSQPFVPLIELTNLRQEMREKEKQLNESLAKIKFLEEKK 1336 Query: 1040 MSMVSDYESKLAQFTTKLENMEEEMQRVSKQL 1071 + +DYE + A+F + ++++E + ++K++ Sbjct: 1337 ANDKADYEVEKARFDKERKSLKELVDMMAKKV 1368 >UniRef50_A2DNX6 Cluster: Viral A-type inclusion protein, putative; n=1; Trichomonas vaginalis G3|Rep: Viral A-type inclusion protein, putative - Trichomonas vaginalis G3 Length = 2923 Score = 158 bits (384), Expect = 1e-36 Identities = 286/1529 (18%), Positives = 638/1529 (41%), Gaps = 134/1529 (8%) Query: 149 NTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXX 208 NTIK+ N L+ ++ ++ TI DL+E++ + E + Sbjct: 1352 NTIKQSKNELTNVRNDLQKANLTINDLEEEMENMRKKNEQQETILQDAQKMVDQLNKQIL 1411 Query: 209 XXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANK-LLEAARFEI 267 ++ TK + E K+++ + K+ E+K ++I + E NK LE ++ Sbjct: 1412 ALKMQNEENETKFKSTIDETENSNKNKELTIRKEYEAKIIQIQTDNEENKSKLEKKYSDL 1471 Query: 268 SLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIE----EKGSLEIANMTE 323 + +E E ++++ S + +TE EK EI N+ + Sbjct: 1472 KNDFENNLKEKETAIMRIQREQKKLTNKMAKALKES-DSRTESVYNELEKSHTEIENLKQ 1530 Query: 324 -LTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKM 382 LT+ ++ L + T + ++ + K + + + IS K Sbjct: 1531 KLTESETKVKSLENSLSMTQSQYNDEQTETSNKHKQMKKTILELNQTISNLETEKIQLKS 1590 Query: 383 KSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXX 442 + S + L+ ++ KN +K +++ LNK++ D + +I++ + Sbjct: 1591 NNESSNDRIKRLSTALEQISKKNNESKEDII--KLNKEIKDAKEIINKLNEQIEDKDDEI 1648 Query: 443 XGKDTLIAQLQLEHQQHMEGPSLI-----HVGTNTEDVNEIAKVQEQLKQELNDEIKDVN 497 L + + + Q + +I + +++E+ V+ +L+ L+D K+ N Sbjct: 1649 NQLKRLQDRYEQQKNQLSQSNEMILKLHDEISEKDRELSEMKSVKRRLQVALDDLDKERN 1708 Query: 498 VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEI 557 IE+L + ++ Q N+ + N + N + +L Q + N K EI Sbjct: 1709 E---IEELHQTQNELKQQNNLLQKENFVKTETIKNLEDELSQTKSHATNLIKTVSEKTEI 1765 Query: 558 VRLTEELHHLSQKVAELEEE-----KGNLQ-----LHLVDYD-SGRMIESDVYKKMIE-- 604 T++ + K + +EE K ++ L+ ++ + ++ E++ KK I Sbjct: 1766 YNSTKQDNDEKDKTIKSQEEIIDKLKNEIKEKTSTLNQINSKFNDKVEENETLKKQISSA 1825 Query: 605 MENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVC----SEIK 660 +N E + S+ K Q++ + Y +++++ +++ + +QV SE K Sbjct: 1826 KQNNEELERRLDSMFSKVKL-FEQQIQDNTKNYQKIDEEKSNLQKTLRNQVVLLDESETK 1884 Query: 661 SVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKD------LENDK-----EDIMNK 709 LE + + + + + L +L+ ++L +D EN+K +D++NK Sbjct: 1885 KHELEIKFNTMKTNFENLQKQFNDLQTKHDELKKENEDQIENLSKENEKFDRNSKDLINK 1944 Query: 710 LQNYIQENMDL-----TDKLE----KMSAEKISELLAKINHEEQSKIQTQFGI-DAKIQE 759 + EN L T KLE K S + + E+ K+++E K +T+ + + K Q Sbjct: 1945 ITQLESENRQLGGDLQTTKLELEDIKRSKQNLQEIYDKVSNE---KSETEKSVRELKKQN 2001 Query: 760 RDL--YIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQ-LGSY--LQEKQ-KAY 813 +DL +E+I + + +I + + +++ + LE + L Y L+EK K Sbjct: 2002 KDLLGQLEDITEKETSANGKISSINSQMKTLKEEKDKLESSNFKLLEDYRTLKEKSIKEI 2061 Query: 814 SEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDM- 872 +E IQ D+L N L + +EK L E++ + L N +L+ ++S+M Sbjct: 2062 NEIKIQNDKLTNENTTLKNEIERIEKSL---ENQKSVNSQNISALTTRNNDLERTISEMR 2118 Query: 873 QQHYNALV---EKANRTDLAESESTKYQTQLRDLE---SNLKRITHEHQTLIVQKKKEIE 926 QQH ++ E ++++ E + ++L+ NL + +E + I ++K E + Sbjct: 2119 QQHMKSISTIGEMTTNDEISKREIRNLKENNKNLQEKIDNLIKNENELKRQISKEKSEKD 2178 Query: 927 DLEIEFNTQIESAIRD----KKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVE-EL 981 + ++ + R +N+ ++N + V+Q+E +L+ KN +++N N+E E+ Sbjct: 2179 QQKSQYENEDHENKRKISELSNQINQLSQENKDLVSQIE-ELKSSKNKSKDINKNLEKEI 2237 Query: 982 NKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMS 1041 +++ +E + +K + + Y+ + ++ + + + ++II + S Sbjct: 2238 DRLRIE--NSQNEKLRISAEKYSAELETKLESIENKHETEKKDIIDRHFAAEQELDSQRI 2295 Query: 1042 MVSDYESKLAQFTTKLENMEEEMQRVS--KQLLDSKQHNEELQILVREQDDQIKELKET- 1098 +S+ E ++ + + + + VS K +D K ++ +Q QI +L T Sbjct: 2296 KISNLEQEIEHYKAVEDELRKRQLTVSPTKSKIDDKNSK-----IIEDQTKQISDLHNTI 2350 Query: 1099 -KLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVL 1157 ++ ++ ++E + S++ N++ L +++ E + + + L Sbjct: 2351 SRMAERFSVVESE---LKSSLSREKTLRNDI----LEIKSESRKLLSEKQNELLSKTNEL 2403 Query: 1158 QEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTV 1217 ++ +L ++ E K ++E L +L N + I L ++ NT D L S + Sbjct: 2404 SKKDNELMVKVSEISQKQNEIEILKEQLNNMSKTNDKTIEDLTKQILDKNTTIDQLKSKL 2463 Query: 1218 AELRSSISSAVDQ-RGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQ 1276 +L S+ DQ + + E Q L+ + + T +ELR Q E + Q+L+ + Sbjct: 2464 IDL----STKSDQSQTIQDLENKLQTLSISTKEKEGTINELRQQ---NEQLHLQILEK-E 2515 Query: 1277 SSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAF-X 1335 S+ + E K+ + +V S ++Q K + N++ + INQIE L E++ K +F Sbjct: 2516 SNIRSEKAKVNHLNEVIS---EIQIKNNN--NVKNNNQEYINQIEQLSRELDSTKRSFIT 2570 Query: 1336 XXXXXXXXXXXXXXXDLRTE-NQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXR 1394 ++R E +++ + E+ +L + E L KS+ Sbjct: 2571 TSNEKNELEKSYHLLEIRLERSETTNKKYEEQVLRMTSEIDDLHKSNDEKQLSIERLNRE 2630 Query: 1395 VNDAEAKVLELTHQLE-----LKD--------SEIYQKTHEYTITLTQRNDEFENVRQQL 1441 + +++ + + +LE L D + ++ + +L Q +++ L Sbjct: 2631 LRSLKSQHISIKTELEETRHLLSDKATTESENDRLKEENEKLQHSLHQTKTSINSMQTNL 2690 Query: 1442 VEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSL 1501 + E+ + + EK ++ +L + N + +++ E E + E + + + Sbjct: 2691 TKIER--DMIPKEKYQDILQSKLYYEQEYNKLKETKQQIENEYRNIDERIRIVHDFIIHY 2748 Query: 1502 NKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFA 1561 N +V ++ K + + + + + +EI L ++ T + ++ +S + + Sbjct: 2749 NYKVGDIRKYVSALIGYLQPLFSIFKYREINF-PLFEKTTKI---LKIASPSLVASIDGN 2804 Query: 1562 SDTKQGRDEQLDNTMNKELLDAVPRAELD 1590 ++ QL +T+ EL +D Sbjct: 2805 KSILGSQETQLLSTVRDELFSITHGGGID 2833 Score = 156 bits (378), Expect = 5e-36 Identities = 282/1484 (19%), Positives = 643/1484 (43%), Gaps = 145/1484 (9%) Query: 212 EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271 E K+ ++ +Q+ + + ++I+ KD+ SSL+ K + + E L Sbjct: 1154 EKMKRDISDLQDTMTTLTTQ----NSEFAREIKDKDLENSSLQYQIKAISDEQNESVLAQ 1209 Query: 272 SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELL 331 ++ ++ + K +E + + E++ K + + ELT ++ Sbjct: 1210 NEQNKKRDLLIAKKQNKIVKLENRMKDLLEKTTKSLQEMDNKNKTLNSKVAELTNELSKS 1269 Query: 332 EHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSS 391 + +I + N E + L E K++ K S+ T + QL+ Sbjct: 1270 KE---EIDKLNNEKSSIL-----EEKSILETEK------SKIEQEKTVILQEKTELQLNF 1315 Query: 392 E-TLNQ-DTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLI 449 E T NQ K +++ E +L+ +I+ N L+++E I + + I Sbjct: 1316 EQTTNQTQLQKDLSQKEFERLQSIIEEKNISLLEQENTIKQSKNELTNVRNDLQKANLTI 1375 Query: 450 AQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQ-LKQELNDEIKDVNVKDLIEKLKSA 508 L+ E ++M + + + ++ +Q L ++ +E + K I++ +++ Sbjct: 1376 NDLE-EEMENMRKKNEQQETILQDAQKMVDQLNKQILALKMQNEENETKFKSTIDETENS 1434 Query: 509 EE--QITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKE--IVRLTEEL 564 + ++T + E +A + +K KL++ + N + + KE I+R+ E Sbjct: 1435 NKNKELT-IRKEYEAKIIQIQTDNEENKSKLEKKYSDLKNDFENNLKEKETAIMRIQREQ 1493 Query: 565 HHLSQKVAE-LEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQK 623 L+ K+A+ L+E + + + ++ +K+ E E ++ ++S+ +SQ Sbjct: 1494 KKLTNKMAKALKESDSRTESVYNELEKSHTEIENLKQKLTESETKVKSLENSLSMTQSQY 1553 Query: 624 FDLVQELHILQQKYDEVEDKLAD-ISQLQSDQVCSEIKSVHLEEQIDALSA-----SKKE 677 D E ++ + +L IS L+++++ + + ++I LS SKK Sbjct: 1554 NDEQTETSNKHKQMKKTILELNQTISNLETEKIQLKSNNESSNDRIKRLSTALEQISKKN 1613 Query: 678 LALVIENLKLDKE-----QLYGTIKDLENDKEDIMNKLQN----YIQENMDLTDKLEKMS 728 + +KL+KE ++ + + DK+D +N+L+ Y Q+ L+ E + Sbjct: 1614 NESKEDIIKLNKEIKDAKEIINKLNEQIEDKDDEINQLKRLQDRYEQQKNQLSQSNEMIL 1673 Query: 729 A--EKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIA 786 ++ISE +++ + K + Q +D +ER+ IE + ++ K + L++ Sbjct: 1674 KLHDEISEKDRELSEMKSVKRRLQVALDDLDKERN-EIEELHQTQNELKQQNNLLQKENF 1732 Query: 787 VMEDRRYSLERKADQLGSYLQEKQKAYSE----YTIQEDELVNRLAVLMDHDRVVEKQLL 842 V + +LE + Q S+ K SE Y + + + + + +++K Sbjct: 1733 VKTETIKNLEDELSQTKSHATNLIKTVSEKTEIYNSTKQDNDEKDKTIKSQEEIIDKLKN 1792 Query: 843 EIEHENKELQKKNQIL---LEENQNLQISLSDMQQHYNALVEKAN----RTDLAESE--- 892 EI+ + L + N +EEN+ L+ +S +Q+ L + + + L E + Sbjct: 1793 EIKEKTSTLNQINSKFNDKVEENETLKKQISSAKQNNEELERRLDSMFSKVKLFEQQIQD 1852 Query: 893 STKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNT------------------ 934 +TK ++ + +SNL++ L+ + + + +LEI+FNT Sbjct: 1853 NTKNYQKIDEEKSNLQKTLRNQVVLLDESETKKHELEIKFNTMKTNFENLQKQFNDLQTK 1912 Query: 935 ------QIESAIRDKKVLNEKYEKN----IEYVTQLEAQLQEYKNNIENLNMNVEEL--N 982 + E I + NEK+++N I +TQLE++ ++ +++ + +E++ + Sbjct: 1913 HDELKKENEDQIENLSKENEKFDRNSKDLINKITQLESENRQLGGDLQTTKLELEDIKRS 1972 Query: 983 KMNLELIDKHVQKQQTQSPDYTEQYINEINKLNA-LLKQKD---EEIIALNQKINNAQVS 1038 K NL+ I V ++++ TE+ + E+ K N LL Q + E+ + N KI++ S Sbjct: 1973 KQNLQEIYDKVSNEKSE----TEKSVRELKKQNKDLLGQLEDITEKETSANGKISSIN-S 2027 Query: 1039 YMSMVSDYESKLAQFTTK-LENMEEEMQRVSKQLLDSKQHNEEL---QILVREQDDQI-K 1093 M + + + KL K LE+ ++ K++ + K N++L ++ + ++I K Sbjct: 2028 QMKTLKEEKDKLESSNFKLLEDYRTLKEKSIKEINEIKIQNDKLTNENTTLKNEIERIEK 2087 Query: 1094 ELKETKLTFEMNIP--KTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFI 1151 L+ K NI T + TI M + + +E Sbjct: 2088 SLENQKSVNSQNISALTTRNNDLERTISEMRQQ-HMKSISTIGEMTTNDEISKREIRNLK 2146 Query: 1152 QERSVLQEQSAKL---NTELQECYTK-IIQLETLNTELTGHDVVNQEQINQLKSKLEQLN 1207 + LQE+ L EL+ +K + + ++ D N+ +I++L +++ QL+ Sbjct: 2147 ENNKNLQEKIDNLIKNENELKRQISKEKSEKDQQKSQYENEDHENKRKISELSNQINQLS 2206 Query: 1208 TENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESK 1267 EN +L+S + EL+SS + + D I + ++ + + + + E +LR+ + ++ Sbjct: 2207 QENKDLVSQIEELKSSKNKSKD-----INKNLEKEIDRLRIENSQNE-KLRISAEKYSAE 2260 Query: 1268 YEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQ---EKYADVINQIEILR 1324 E L+S+++ + ET K +++ + + +L + + NL+ E Y V +++ + Sbjct: 2261 LETKLESIEN--KHETEKKDIIDRHFAAEQELDSQRIKISNLEQEIEHYKAVEDELRKRQ 2318 Query: 1325 SEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXX 1384 + K DL N + + S++ +++ ++ + Sbjct: 2319 LTVSPTKSKIDDKNSKIIEDQTKQISDL--HNTISRMAERFSVVESELKSSLSREKTLRN 2376 Query: 1385 XXXXXXXXXR--VNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLV 1442 R +++ + ++L T++L KD+E+ K E ++Q+ +E E +++QL Sbjct: 2377 DILEIKSESRKLLSEKQNELLSKTNELSKKDNELMVKVSE----ISQKQNEIEILKEQLN 2432 Query: 1443 EY----EKRIEDLT---YEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKI 1495 +K IEDLT +K + + L+ K+ + + + Q ++E ++ L++ Sbjct: 2433 NMSKTNDKTIEDLTKQILDKNTTIDQLKSKLIDLSTKSDQSQTIQDLE--NKLQTLSIST 2490 Query: 1496 TESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQ 1555 E ++ + N+ L ++ E ++ + +++ ++ LN+ I+ +Q ++ +++ Sbjct: 2491 KEKEGTINELRQQNEQLHLQIL---EKESNIRSEKAKVNHLNEVISEIQ--IKNNNNVKN 2545 Query: 1556 KHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDLAMYMLHQR 1599 + + + +Q +LD+T + + + EL+ + ++L R Sbjct: 2546 NNQEYINQIEQ-LSRELDSTKRSFITTSNEKNELEKSYHLLEIR 2588 Score = 154 bits (374), Expect = 2e-35 Identities = 224/1019 (21%), Positives = 440/1019 (43%), Gaps = 91/1019 (8%) Query: 141 LGDVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKI-NEKDQIIEAKNKATTXXXXX 199 L D+ N I+E + L+ + +++ E I N +D++ + K+ AT Sbjct: 1700 LDDLDKERNEIEELHQTQNELKQQNNLLQKENFVKTETIKNLEDELSQTKSHATNLIKTV 1759 Query: 200 XXXXXXXXXXXXE-DTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANK 258 + D K + K QE I EK L I SK + E N+ Sbjct: 1760 SEKTEIYNSTKQDNDEKDKTIKSQEEIIDKLKNEIKEKTSTLNQINSK---FNDKVEENE 1816 Query: 259 LLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEI 318 L+ + +L + L+ K + + EEK+ +++ ++ Sbjct: 1817 TLKKQISSAKQNNEELERRLDSMFSKVKLFEQQIQDNTK-NYQKIDEEKSNLQKTLRNQV 1875 Query: 319 ANMTEL-TKKIELLEHLNCQIRQTNKE-LE---NKLATMGTESKAVSSPSKKGSPLISRK 373 + E TKK EL N +TN E L+ N L T E K + + + K Sbjct: 1876 VLLDESETKKHELEIKFNTM--KTNFENLQKQFNDLQTKHDELKKENEDQIENLSKENEK 1933 Query: 374 SGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEK-D 432 RN+ + +QL SE D + K E+ ++ Q+L +++ DK V +EK + Sbjct: 1934 FDRNSKDLINKI-TQLESENRQLGGDLQTTKLELEDIKRSKQNL-QEIYDK--VSNEKSE 1989 Query: 433 TXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLK--QELN 490 T KD L QLE E T +I+ + Q+K +E Sbjct: 1990 TEKSVRELKKQNKDLLG---QLEDITEKE----------TSANGKISSINSQMKTLKEEK 2036 Query: 491 DEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKV 550 D+++ N K L+E ++ +E+ + +EI N + + K ++++++K+++N V Sbjct: 2037 DKLESSNFK-LLEDYRTLKEKSIKEINEIKIQNDKLTNENTTLKNEIERIEKSLENQKSV 2095 Query: 551 SDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDS-GRMIESDVYKKMIEMENLA 609 + N I LT + L + ++E+ ++ H+ + G M +D K E+ NL Sbjct: 2096 NSQN--ISALTTRNNDLERTISEMRQQ------HMKSISTIGEMTTNDEISKR-EIRNLK 2146 Query: 610 ETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQID 669 E +++ + E + +Q E +K SQ +++ ++ K L QI+ Sbjct: 2147 ENNKNLQEKIDNL---IKNENELKRQISKEKSEKDQQKSQYENEDHENKRKISELSNQIN 2203 Query: 670 ALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSA 729 LS K+L IE LK K + KD+ + E +++L+ +N L EK SA Sbjct: 2204 QLSQENKDLVSQIEELKSSKNKS----KDINKNLEKEIDRLRIENSQNEKLRISAEKYSA 2259 Query: 730 EKISELLAKIN-HEEQSK--IQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIA 786 E ++L + N HE + K I F + ++ + + I N+E E+ YK+ L + Sbjct: 2260 ELETKLESIENKHETEKKDIIDRHFAAEQELDSQRIKISNLEQEIEHYKAVEDELRKRQL 2319 Query: 787 VMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVL-------MDHDRVVEK 839 + + ++ K ++ ++++ K S+ + R +V+ + ++ + Sbjct: 2320 TVSPTKSKIDDKNSKI---IEDQTKQISDLHNTISRMAERFSVVESELKSSLSREKTLRN 2376 Query: 840 QLLEIEHENKEL--QKKNQILLEENQ------NLQISLSDMQQHYNA---LVEKANRTDL 888 +LEI+ E+++L +K+N++L + N+ L + +S++ Q N L E+ N Sbjct: 2377 DILEIKSESRKLLSEKQNELLSKTNELSKKDNELMVKVSEISQKQNEIEILKEQLNNMSK 2436 Query: 889 AESESTKYQT-QLRDLESNLKRITHEHQTLIVQ--KKKEIEDLEIEFNTQIESAIRDKKV 945 ++ + T Q+ D + + ++ + L + + + I+DLE + T S + Sbjct: 2437 TNDKTIEDLTKQILDKNTTIDQLKSKLIDLSTKSDQSQTIQDLENKLQTLSISTKEKEGT 2496 Query: 946 LNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTE 1005 +NE ++N QL Q+ E ++NI + V LN E+I + K + + Sbjct: 2497 INELRQQN----EQLHLQILEKESNIRSEKAKVNHLN----EVISEIQIKNNNNVKNNNQ 2548 Query: 1006 QYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQ 1065 +YIN+I +L+ L I + + N + SY + E +L + T + EE++ Sbjct: 2549 EYINQIEQLSRELDSTKRSFITTSNEKNELEKSYHLL----EIRLERSETTNKKYEEQVL 2604 Query: 1066 RVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMII-SSTIEPMSD 1123 R++ ++ D + N+E Q+ + + +++ LK ++ + + +T ++ +T E +D Sbjct: 2605 RMTSEIDDLHKSNDEKQLSIERLNRELRSLKSQHISIKTELEETRHLLSDKATTESEND 2663 Score = 132 bits (319), Expect = 8e-29 Identities = 286/1512 (18%), Positives = 623/1512 (41%), Gaps = 151/1512 (9%) Query: 147 LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXX 206 L+ K+ N + L K+K + + LQ N+ Q + K Sbjct: 519 LNTKDKDNQNNIKKLLKKLKENDLKLKGLQNDNNKIKQQNQDLLKKIESQEEEKQKLQEL 578 Query: 207 XXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRL-LKDIESKDVRISSL--EEANKLLEAA 263 E+ K Q+ K+++ E E + K ++ L + + D +++ E+AN++L+ Sbjct: 579 KDNEIENMKDQIKKLKQILAKNENEKSELKNQISLLENDKNDDKLNDAIKEQANEILQLK 638 Query: 264 ------RFEISLEHSKLAQELE-QXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSL 316 + + E S+L + E Q L + S E + Sbjct: 639 EQLDDNKIKFENEKSELTKNYEDQLKYLRKQVQNLCKDLVPDAKHSSTNPNDFNNEFNLI 698 Query: 317 EIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISR--KS 374 + +LT L HLN + N+ L E + + ++ R ++ Sbjct: 699 KDLLNDKLTVIQNLTNHLNGLQNKVNEVATEHLNEANNEPIYALTQISRLILMLKRMNET 758 Query: 375 GRNTASKMKSPWSQLSSET-LNQDTDKKI-NKNEIAK-LEMVIQSLNKDLVDKEYVISEK 431 + +K+K + L + N + +K+ ++N+ K LE ++ LN L IS+ Sbjct: 759 VNSENNKLKDQVNYLQKDNDKNGVSIRKLQDENDRMKYLENLVNDLNNKLNSAYQAISDY 818 Query: 432 DTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELND 491 + + LQ+ +Q + +++ E+ + + L+ ++ Sbjct: 819 EIASKNNDALAKKVSEIKLSLQVAAKQIQKYEKA------AQELGEVKNLNDSLRDSISK 872 Query: 492 EIKDVNVKDLIEKLKSAEEQITQLND--EIDAANKNMIKVKSN-----HKLKLKQMQKTI 544 KDV +K+L +LK + + + + + ++N +K N HK +++ ++ I Sbjct: 873 --KDVKIKELTVELKDLQRKSVEFDSFRQKSENDQNTLKDLQNENQFLHK-EIENLKSDI 929 Query: 545 DNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIE 604 N K D+ + + E+ SQ E K L D D+ +D+ K+I Sbjct: 930 KNKDKTIDTFQSQILEQTEVFARSQTAIENAMNKSKL-----DDDT----INDMKAKLIS 980 Query: 605 MENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQ----LQSDQVCSEIK 660 N E LK LE + ++ H LQ+K EV +K+ + + S V I Sbjct: 981 CRNALEDSLKREDSLEKDIQKVKEKYHKLQEKVTEVTNKIVPVETSVIIINSGSVSQNIS 1040 Query: 661 SVHLEEQIDALSASK-KELALVIENLKLDKEQLYGTIKDLENDKEDIM----NKLQNYIQ 715 + +I + K K L + + E+L + D+ + + + NKL + Sbjct: 1041 DLDSLYKIFTQNDEKIKNLTEKVTQTTENYEKLRKVLTDILSRFDTLSPMDDNKLIEVVM 1100 Query: 716 ENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYK 775 + ++ K + K+ E++ N+ + S ++ DL + +++ K K Sbjct: 1101 NDFNVLTKEIEFVRSKLIEIVK--NNTDLSNLKHMNSKKLLNIIIDL-LNQSKADNEKMK 1157 Query: 776 SRICRLEESIAVM--EDRRYSLERKADQL-GSYLQEKQKAYSEYTIQEDELVNRLAVLMD 832 I L++++ + ++ ++ E K L S LQ + KA S+ Q + ++ + Sbjct: 1158 RDISDLQDTMTTLTTQNSEFAREIKDKDLENSSLQYQIKAISDE--QNESVLAQNEQNKK 1215 Query: 833 HDRVVEK---QLLEIEHENKELQKKNQILLEENQNLQISL-SDMQQHYNALVEKANRTDL 888 D ++ K +++++E+ K+L +K L+E N +L S + + N L + D Sbjct: 1216 RDLLIAKKQNKIVKLENRMKDLLEKTTKSLQEMDNKNKTLNSKVAELTNELSKSKEEIDK 1275 Query: 889 AESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIE-DLEIEFN-TQIESAIRDKK-- 944 +E + + LE+ +I E +T+I+Q+K E++ + E N TQ++ + K+ Sbjct: 1276 LNNEKSSILEEKSILETEKSKIEQE-KTVILQEKTELQLNFEQTTNQTQLQKDLSQKEFE 1334 Query: 945 ----VLNEKYEKNIEY---VTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQ 997 ++ EK +E + Q + +L +N+++ N+ + +L + +E + K ++Q+ Sbjct: 1335 RLQSIIEEKNISLLEQENTIKQSKNELTNVRNDLQKANLTINDLEE-EMENMRKKNEQQE 1393 Query: 998 TQSPDYTEQYINEINKLNALLKQKDEE-----IIALNQKINNAQVSYMSMVSDYESKLAQ 1052 T D ++ ++++NK LK ++EE +++ N+ + +++ +YE+K+ Q Sbjct: 1394 TILQD-AQKMVDQLNKQILALKMQNEENETKFKSTIDETENSNKNKELTIRKEYEAKIIQ 1452 Query: 1053 FTTKLENMEEEMQRVSKQLLDSKQHN--EELQILVREQDDQIKELKETKLTFEMNIPKTE 1110 T E + ++++ L + ++N E+ ++R Q +Q K + + + +TE Sbjct: 1453 IQTDNEENKSKLEKKYSDLKNDFENNLKEKETAIMRIQREQKKLTNKMAKALKESDSRTE 1512 Query: 1111 GMIISSTIEPMSDDANNVDXXXXXXXXXXXXLK---VQEEEEFIQERSVLQEQSAKLNTE 1167 + + +E + N+ L+ + ++ E++ + ++ Sbjct: 1513 S--VYNELEKSHTEIENLKQKLTESETKVKSLENSLSMTQSQYNDEQTETSNKHKQMKKT 1570 Query: 1168 LQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSA 1227 + E I LET +L ++ + ++I +L + LEQ++ +N+ + +L I A Sbjct: 1571 ILELNQTISNLETEKIQLKSNNESSNDRIKRLSTALEQISKKNNESKEDIIKLNKEIKDA 1630 Query: 1228 VDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIV 1287 K+ + + + + E+ QL + +YEQ Q + ++N Sbjct: 1631 ------------KEIINKLNEQIEDKDDEIN-QLKRLQDRYEQ-----QKNQLSQSN--- 1669 Query: 1288 TMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXX 1347 E + L +++ +K+ L ++ V ++++ +++ E+ Sbjct: 1670 --EMILKLHDEISEKDRELSEMK----SVKRRLQVALDDLDKER--------NEIEELHQ 1715 Query: 1348 XXXDLRTEN---QSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVN----DAEA 1400 +L+ +N Q ++ ++I N+ +E +Q K + N D + Sbjct: 1716 TQNELKQQNNLLQKENFVKTETIKNLEDELSQTKSHATNLIKTVSEKTEIYNSTKQDNDE 1775 Query: 1401 KVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELA 1460 K + Q E+ D ++ + E T TL Q N +F +K E+ T +K+ A Sbjct: 1776 KDKTIKSQEEIID-KLKNEIKEKTSTLNQINSKFN---------DKVEENETLKKQISSA 1825 Query: 1461 ILRLKMHENANHYETMQKESEIERVKLIEELNVKITESV-SLNKQVAELNKALEEEVAKT 1519 +N E + +S +VKL E+ T++ ++++ + L K L +V Sbjct: 1826 ------KQNNEELE-RRLDSMFSKVKLFEQQIQDNTKNYQKIDEEKSNLQKTLRNQVVLL 1878 Query: 1520 NEMQTALENQEIEIVTLNDEITNLQ---NMVRASSSKIQKHVSFASDTKQGRDEQLDNTM 1576 +E +T EI+ T+ NLQ N ++ +++K + +E+ D Sbjct: 1879 DESETKKHELEIKFNTMKTNFENLQKQFNDLQTKHDELKKENEDQIENLSKENEKFDRN- 1937 Query: 1577 NKELLDAVPRAE 1588 +K+L++ + + E Sbjct: 1938 SKDLINKITQLE 1949 Score = 131 bits (317), Expect = 1e-28 Identities = 289/1376 (21%), Positives = 572/1376 (41%), Gaps = 169/1376 (12%) Query: 338 IRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSET--LN 395 I Q + + T T SP + + ++ K++ QL+S+T L Sbjct: 326 INQMENDQQQSRKTDSTTIHVTQSPVVQQRMKVLQERNLQLEEKLRQTNDQLNSQTAPLT 385 Query: 396 Q-DTDKKINKNEIAKLEMVIQSLNKD-LVDK--EYVISEKDTXXXXXXXXXXGKDTLIAQ 451 Q + N I +L+ ++S N D +K + +++E+ I + Sbjct: 386 QLQQNNSQNNTTIVELDSDLESSNSDDEAEKLSKLLMTERSEAEQRLADERDQLKKQIEE 445 Query: 452 LQ-----LEHQQHMEGPSLIHVGTNTEDVN----EIAKVQEQLKQELNDEIKDV-----N 497 +Q +++ + + L +N +D N EIAK + Q+K E++ +I+++ N Sbjct: 446 MQNKIDKMQNDINDKDQQLTQFYSNYDDRNMLKDEIAKKENQIK-EISKQIEEMKKLKEN 504 Query: 498 VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEI 557 K I LKS E++ + + K ++K + LKLK +Q DN +K+ N+++ Sbjct: 505 DKSDISTLKSLNEELNTKDKDNQNNIKKLLKKLKENDLKLKGLQN--DN-NKIKQQNQDL 561 Query: 558 VRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAE-TRLK-A 615 ++ K+ EEEK LQ L D + M + K I +N E + LK Sbjct: 562 LK----------KIESQEEEKQKLQ-ELKDNEIENMKDQIKKLKQILAKNENEKSELKNQ 610 Query: 616 ISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQI-DALSAS 674 ISLLE+ K D I +Q + ++ K QL +++ E + L + D L Sbjct: 611 ISLLENDKNDDKLNDAIKEQANEILQLK----EQLDDNKIKFENEKSELTKNYEDQLKYL 666 Query: 675 KKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISE 734 +K++ + ++L D + D N+ I + L + + +LT+ L + K++E Sbjct: 667 RKQVQNLCKDLVPDAKHSSTNPNDFNNEFNLIKDLLNDKLTVIQNLTNHLNGLQ-NKVNE 725 Query: 735 LLAK-INHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEE-------SIA 786 + + +N I I I E + SE +K K ++ L++ SI Sbjct: 726 VATEHLNEANNEPIYALTQISRLILMLKRMNETVNSENNKLKDQVNYLQKDNDKNGVSIR 785 Query: 787 VME---DRRYSLERKADQLGSYLQEKQKAYSEYTI---QEDELVNRLAVLMDHDRVVEKQ 840 ++ DR LE + L + L +A S+Y I D L +++ + +V KQ Sbjct: 786 KLQDENDRMKYLENLVNDLNNKLNSAYQAISDYEIASKNNDALAKKVSEIKLSLQVAAKQ 845 Query: 841 LLEIE---HENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQ 897 + + E E E++ N L + + + ++ L K+ D +S Q Sbjct: 846 IQKYEKAAQELGEVKNLNDSLRDSISKKDVKIKELTVELKDLQRKSVEFDSFRQKSENDQ 905 Query: 898 TQLRDLES----------NLKR-ITHEHQTLIVQKKKEIEDLEI--EFNTQIESAIRDKK 944 L+DL++ NLK I ++ +T+ + + +E E+ T IE+A+ K Sbjct: 906 NTLKDLQNENQFLHKEIENLKSDIKNKDKTIDTFQSQILEQTEVFARSQTAIENAMNKSK 965 Query: 945 V----LNEKYEKNIEYVTQLEAQLQ---EYKNNIENLNMNVEELNKMNLELIDKHVQKQQ 997 + +N+ K I LE L+ + +I+ + +L + E+ +K V + Sbjct: 966 LDDDTINDMKAKLISCRNALEDSLKREDSLEKDIQKVKEKYHKLQEKVTEVTNKIVPVET 1025 Query: 998 TQ---SPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFT 1054 + + Q I++++ L + Q DE+I L +K+ +Y + L++F Sbjct: 1026 SVIIINSGSVSQNISDLDSLYKIFTQNDEKIKNLTEKVTQTTENYEKLRKVLTDILSRFD 1085 Query: 1055 T-------KL--------ENMEEEMQRVSKQLLDSKQHNEELQILVREQD--------DQ 1091 T KL + +E++ V +L++ ++N +L L D Sbjct: 1086 TLSPMDDNKLIEVVMNDFNVLTKEIEFVRSKLIEIVKNNTDLSNLKHMNSKKLLNIIIDL 1145 Query: 1092 IKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFI 1151 + + K + +I + + + T + S+ A + +K +E Sbjct: 1146 LNQSKADNEKMKRDISDLQDTMTTLTTQ-NSEFAREIKDKDLENSSLQYQIKAISDE--- 1201 Query: 1152 QERSVL--QEQSAKLNTELQECYTKIIQLETLNTELTGHDVVN-QEQINQ---LKSKLEQ 1205 Q SVL EQ+ K + + + KI++LE +L + QE N+ L SK+ + Sbjct: 1202 QNESVLAQNEQNKKRDLLIAKKQNKIVKLENRMKDLLEKTTKSLQEMDNKNKTLNSKVAE 1261 Query: 1206 LNTENDNLLSTVAELRSSISSAVDQRGFEIAELWK---------QHLAQREADFQKTEHE 1256 L E + +L + SS ++++ E K Q + + +F++T ++ Sbjct: 1262 LTNELSKSKEEIDKLNNEKSSILEEKSILETEKSKIEQEKTVILQEKTELQLNFEQTTNQ 1321 Query: 1257 LRVQLSAFESKYEQLLDSVQS---STQEETNKI-VTMEQVTSLQNKLQ-------DKEEH 1305 ++Q + ++E+L ++ S E+ N I + ++T+++N LQ D EE Sbjct: 1322 TQLQKDLSQKEFERLQSIIEEKNISLLEQENTIKQSKNELTNVRNDLQKANLTINDLEEE 1381 Query: 1306 LRNLQ-------------EKYADVIN-QIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXD 1351 + N++ +K D +N QI L+ + E+ + F Sbjct: 1382 MENMRKKNEQQETILQDAQKMVDQLNKQILALKMQNEENETKFKSTIDETENSNKNKELT 1441 Query: 1352 LRTENQS-YKQMQ---EQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTH 1407 +R E ++ Q+Q E++ + ++ + LK R+ + K LT+ Sbjct: 1442 IRKEYEAKIIQIQTDNEENKSKLEKKYSDLKNDFENNLKEKETAIMRIQREQKK---LTN 1498 Query: 1408 QLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMH 1467 ++ E +T L + + E EN++Q+L E E +++ L + + Sbjct: 1499 KMAKALKESDSRTESVYNELEKSHTEIENLKQKLTESETKVKSLENSLSMTQSQYNDEQT 1558 Query: 1468 ENANHYETMQKE-SEI-ERVKLIEELNVKI-TESVSLNKQVAELNKALEEEVAKTNEMQT 1524 E +N ++ M+K E+ + + +E +++ + + S N ++ L+ ALE+ K NE + Sbjct: 1559 ETSNKHKQMKKTILELNQTISNLETEKIQLKSNNESSNDRIKRLSTALEQISKKNNESKE 1618 Query: 1525 ALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTK--QGRDEQLDNTMNK 1578 +I+ LN EI + + ++ + +I+ + K Q R EQ N +++ Sbjct: 1619 -------DIIKLNKEIKDAKEIINKLNEQIEDKDDEINQLKRLQDRYEQQKNQLSQ 1667 Score = 125 bits (302), Expect = 9e-27 Identities = 278/1498 (18%), Positives = 613/1498 (40%), Gaps = 135/1498 (9%) Query: 160 VLQVKMKIMETTILDLQEKINE-KDQI---------IEAKNKATTXXXXXXXXXXXXXXX 209 V+Q +MK+++ L L+EK+ + DQ+ ++ N Sbjct: 351 VVQQRMKVLQERNLQLEEKLRQTNDQLNSQTAPLTQLQQNNSQNNTTIVELDSDLESSNS 410 Query: 210 XXEDTKQQMTKMQENFIAMEAEWKDEKQRLLK--------------DIESKDVRI----S 251 E K M E A E DE+ +L K DI KD ++ S Sbjct: 411 DDEAEKLSKLLMTERSEA-EQRLADERDQLKKQIEEMQNKIDKMQNDINDKDQQLTQFYS 469 Query: 252 SLEEANKLL-EAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEI 310 + ++ N L E A+ E ++ ++++++E+ L + E + ++K Sbjct: 470 NYDDRNMLKDEIAKKENQIK--EISKQIEEMKKLKENDKSDISTLKSLNEELNTKDKDNQ 527 Query: 311 EEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLI 370 L + + E K++ L++ N +I+Q N++L K+ + E + + K + + Sbjct: 528 NNIKKL-LKKLKENDLKLKGLQNDNNKIKQQNQDLLKKIESQEEEKQKLQ--ELKDNEIE 584 Query: 371 SRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISE 430 + K ++ + SE NQ + + +KN+ + + + N+ L KE + Sbjct: 585 NMKDQIKKLKQILAKNENEKSELKNQISLLENDKNDDKLNDAIKEQANEILQLKEQLDDN 644 Query: 431 KDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEG--PSLIHVGTNTEDVNEIAKVQEQLKQE 488 K + + L+ + Q + P H TN D N + +K Sbjct: 645 KIKFENEKSELTKNYEDQLKYLRKQVQNLCKDLVPDAKHSSTNPNDFNNEFNL---IKDL 701 Query: 489 LNDEIKDVNVKDLIEKLKSAEEQITQL-NDEIDAANKNMIKVK---SNHKLKLKQMQKTI 544 LND++ +++L L + ++ ++ + ++ AN I S L LK+M +T+ Sbjct: 702 LNDKL--TVIQNLTNHLNGLQNKVNEVATEHLNEANNEPIYALTQISRLILMLKRMNETV 759 Query: 545 DNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIE 604 ++ + ++ + + +S + + E ++ +LV+ D + S Y+ + + Sbjct: 760 NSENNKLKDQVNYLQKDNDKNGVSIRKLQDENDRMKYLENLVN-DLNNKLNS-AYQAISD 817 Query: 605 MENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEI--KSV 662 E +A A++ S+ +Q QKY++ +L ++ L +D + I K V Sbjct: 818 YE-IASKNNDALAKKVSEIKLSLQVAAKQIQKYEKAAQELGEVKNL-NDSLRDSISKKDV 875 Query: 663 HLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQE--NMDL 720 ++E L +++ ++ ++ + E T+KDL+N+ + + +++N + N D Sbjct: 876 KIKELTVELKDLQRK-SVEFDSFRQKSENDQNTLKDLQNENQFLHKEIENLKSDIKNKDK 934 Query: 721 T-DKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRIC 779 T D + E+ +E+ A+ ++ + D I + + + + L R Sbjct: 935 TIDTFQSQILEQ-TEVFARSQTAIENAMNKSKLDDDTINDMKAKLISCRNALEDSLKRED 993 Query: 780 RLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEK 839 LE+ I ++++ + L+ K ++ + + + S I + ++ D D + K Sbjct: 994 SLEKDIQKVKEKYHKLQEKVTEVTNKIVPVET--SVIIINSGSVSQNIS---DLDSLY-K 1047 Query: 840 QLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNAL--VEKANRTDLAESESTKYQ 897 + + + K L +K E + L+ L+D+ ++ L ++ ++ ++ Sbjct: 1048 IFTQNDEKIKNLTEKVTQTTENYEKLRKVLTDILSRFDTLSPMDDNKLIEVVMNDFNVLT 1107 Query: 898 TQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNI--- 954 ++ + S L I + L K + L N I+ + K NEK +++I Sbjct: 1108 KEIEFVRSKLIEIVKNNTDLSNLKHMNSKKL---LNIIID-LLNQSKADNEKMKRDISDL 1163 Query: 955 -EYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEIN- 1012 + +T L Q E+ I++ ++L +L+ K + +Q +S Q NE N Sbjct: 1164 QDTMTTLTTQNSEFAREIKD-----KDLENSSLQYQIKAISDEQNES--VLAQ--NEQNK 1214 Query: 1013 KLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLL 1072 K + L+ +K +I+ L ++ + + + ++K +K+ + E+ + SK+ + Sbjct: 1215 KRDLLIAKKQNKIVKLENRMKDLLEKTTKSLQEMDNKNKTLNSKVAELTNELSK-SKEEI 1273 Query: 1073 DSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXX 1132 D K +NE+ IL ++ I E +++K+ E + E + E ++ Sbjct: 1274 D-KLNNEKSSIL---EEKSILETEKSKIEQEKTVILQEKTELQLNFEQTTNQTQLQKDLS 1329 Query: 1133 XXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVN 1192 + ++ +++ + +++ +L + + + L E+ N Sbjct: 1330 QKEFERLQSIIEEKNISLLEQENTIKQSKNELTNVRNDLQKANLTINDLEEEMENMRKKN 1389 Query: 1193 QEQ---INQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREAD 1249 ++Q + + ++QLN + L E + S +D+ + EA Sbjct: 1390 EQQETILQDAQKMVDQLNKQILALKMQNEENETKFKSTIDETENSNKNKELTIRKEYEAK 1449 Query: 1250 FQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDK-EEHLRN 1308 + + + S E KY L + +++ +E+ I+ +++ Q KL +K + L+ Sbjct: 1450 IIQIQTDNEENKSKLEKKYSDLKNDFENNLKEKETAIMRIQRE---QKKLTNKMAKALKE 1506 Query: 1309 LQEKYADVINQIEILRSEIEDEKVAFXXXXX------XXXXXXXXXXXDLRTE-NQSYKQ 1361 + V N++E +EIE+ K D +TE + +KQ Sbjct: 1507 SDSRTESVYNELEKSHTEIENLKQKLTESETKVKSLENSLSMTQSQYNDEQTETSNKHKQ 1566 Query: 1362 MQE------QSILNINEENAQLKKSSXXX-------XXXXXXXXXRVNDAEAKVLELTHQ 1408 M++ Q+I N+ E QLK ++ + N+++ +++L Sbjct: 1567 MKKTILELNQTISNLETEKIQLKSNNESSNDRIKRLSTALEQISKKNNESKEDIIKLNK- 1625 Query: 1409 LELKDS-EIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMH 1467 E+KD+ EI K +E + ++DE +++ YE++ L+ E + LK+H Sbjct: 1626 -EIKDAKEIINKLNE---QIEDKDDEINQLKRLQDRYEQQKNQLSQSNE-----MILKLH 1676 Query: 1468 ENANHYETMQKESEIERVKLIE-ELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTAL 1526 + E +K+ E+ +K ++ L V + + ++ EL++ E + N +Q Sbjct: 1677 D-----EISEKDRELSEMKSVKRRLQVALDDLDKERNEIEELHQTQNELKQQNNLLQKEN 1731 Query: 1527 ENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTM--NKELLD 1582 + I L DE++ ++ + + + TKQ DE+ D T+ +E++D Sbjct: 1732 FVKTETIKNLEDELSQTKSHATNLIKTVSEKTEIYNSTKQDNDEK-DKTIKSQEEIID 1788 Score = 84.2 bits (199), Expect = 3e-14 Identities = 198/1121 (17%), Positives = 430/1121 (38%), Gaps = 117/1121 (10%) Query: 516 NDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELE 575 N E+ + N+ +++ + KL + Q + K S++ EE L ++AEL+ Sbjct: 207 NQELASQNEKLVRENTQLKLNISQNSMNASSDQKFSENLNLNSANDEEKEKLRSQLAELQ 266 Query: 576 EEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQ 635 K N Q + +S + + + +++ I++L + L E L+Q Sbjct: 267 S-KINKQ----NANSQEIFAQQISQAKEQLQKFQTD----IAILIDKNNKLKDENTKLKQ 317 Query: 636 KYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGT 695 E + ++ I+Q+++DQ S + ++ L NL+L+ E+L T Sbjct: 318 ---ETQQQMYFINQMENDQQQSRKTDSTTIHVTQSPVVQQRMKVLQERNLQLE-EKLRQT 373 Query: 696 IKDLENDKEDIMNKLQNYIQEN---MDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFG 752 L + + QN Q N ++L LE +++ +E L+K+ E+S+ + + Sbjct: 374 NDQLNSQTAPLTQLQQNNSQNNTTIVELDSDLESSNSDDEAEKLSKLLMTERSEAEQRLA 433 Query: 753 IDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKA 812 ERD ++ ++ + +++I +++ I K QL + Sbjct: 434 -----DERD----QLKKQIEEMQNKIDKMQNDI----------NDKDQQLTQFYSN---- 470 Query: 813 YSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDM 872 Y + + +DE+ + + + + KQ+ E++ + + L N+ L D Sbjct: 471 YDDRNMLKDEIAKK----ENQIKEISKQIEEMKKLKENDKSDISTLKSLNEELNTKDKDN 526 Query: 873 QQHYNALVEKANRTDL----AESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDL 928 Q + L++K DL ++++ K + Q +DL ++ E Q L K EIE++ Sbjct: 527 QNNIKKLLKKLKENDLKLKGLQNDNNKIKQQNQDLLKKIESQEEEKQKLQELKDNEIENM 586 Query: 929 -----------------EIEFNTQIESAIRDKK--VLNEKYEKNIEYVTQLEAQLQEYKN 969 + E QI DK LN+ ++ + QL+ QL + K Sbjct: 587 KDQIKKLKQILAKNENEKSELKNQISLLENDKNDDKLNDAIKEQANEILQLKEQLDDNKI 646 Query: 970 NIENLNMNVEELNKMNLELIDKHVQK-------QQTQSPDYTEQYINEINKLNALLKQK- 1021 EN + + + L+ + K VQ S + NE N + LL K Sbjct: 647 KFENEKSELTKNYEDQLKYLRKQVQNLCKDLVPDAKHSSTNPNDFNNEFNLIKDLLNDKL 706 Query: 1022 ------DEEIIALNQKINNAQVSYMSMVSDYE----SKLAQFTTKLENMEEEMQRVSKQL 1071 + L K+N +++ ++ +++++ L+ M E + + +L Sbjct: 707 TVIQNLTNHLNGLQNKVNEVATEHLNEANNEPIYALTQISRLILMLKRMNETVNSENNKL 766 Query: 1072 LDS----KQHNEELQILVR---EQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDD 1124 D ++ N++ + +R +++D++K L+ + I I ++D Sbjct: 767 KDQVNYLQKDNDKNGVSIRKLQDENDRMKYLENLVNDLNNKLNSAYQAISDYEIASKNND 826 Query: 1125 ANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKI----IQLET 1180 A ++Q+ E+ QE ++ + L + + KI ++L+ Sbjct: 827 ALAKKVSEIKLSLQVAAKQIQKYEKAAQELGEVKNLNDSLRDSISKKDVKIKELTVELKD 886 Query: 1181 LNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWK 1240 L + D Q+ N ++ L+ L EN L + L+S I + + I Sbjct: 887 LQRKSVEFDSFRQKSEND-QNTLKDLQNENQFLHKEIENLKSDIKN----KDKTIDTFQS 941 Query: 1241 QHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQ 1300 Q L Q E F +++ + ++ + + + D ++++ SL+ +Q Sbjct: 942 QILEQTEV-FARSQTAIENAMNKSKLDDDTINDMKAKLISCRNALEDSLKREDSLEKDIQ 1000 Query: 1301 DKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYK 1360 +E LQEK +V N+I +E + + T+N Sbjct: 1001 KVKEKYHKLQEKVTEVTNKI----VPVETSVIIINSGSVSQNISDLDSLYKIFTQNDEKI 1056 Query: 1361 QMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKT 1420 + + + E +L+K ++ +V+ + K+ E + Sbjct: 1057 KNLTEKVTQTTENYEKLRKVLTDILSRFDTLSPMDDNKLIEVVMNDFNVLTKEIEFVRSK 1116 Query: 1421 HEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKES 1480 I + + N + N++ K++ ++ + ++ KM + + + Sbjct: 1117 ---LIEIVKNNTDLSNLKHM---NSKKLLNIIIDLLNQSKADNEKMKRDISDLQDTMTTL 1170 Query: 1481 EIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEI 1540 + + E+ K E+ SL Q+ ++ E V NE + +++ I ++I Sbjct: 1171 TTQNSEFAREIKDKDLENSSLQYQIKAISDEQNESVLAQNEQN---KKRDLLIAKKQNKI 1227 Query: 1541 TNLQNMVR---ASSSKIQKHVSFASDTKQGRDEQLDNTMNK 1578 L+N ++ ++K + + + T + +L N ++K Sbjct: 1228 VKLENRMKDLLEKTTKSLQEMDNKNKTLNSKVAELTNELSK 1268 Score = 48.0 bits (109), Expect = 0.002 Identities = 89/435 (20%), Positives = 171/435 (39%), Gaps = 33/435 (7%) Query: 1165 NTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSI 1224 NT+ + L +L+ E T N+ + + L QLNT N + + E R Sbjct: 135 NTDSIISLVPLTNLRSLDLEGTQLSF-NESVLLFITFTLPQLNTLNRDTIQL--EYRRKA 191 Query: 1225 SSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLS------AFESKYEQLLDSVQSS 1278 + + Q LA + + +L++ +S + + K+ + L+ + S+ Sbjct: 192 AERYSRSQLNDLYRENQELASQNEKLVRENTQLKLNISQNSMNASSDQKFSENLN-LNSA 250 Query: 1279 TQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXX 1338 EE K+ Q+ LQ+K+ + N QE +A I+Q + + + + Sbjct: 251 NDEEKEKL--RSQLAELQSKINKQNA---NSQEIFAQQISQAKEQLQKFQTD-------- 297 Query: 1339 XXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDA 1398 L+ EN KQ +Q + IN+ ++S V Sbjct: 298 ---IAILIDKNNKLKDENTKLKQETQQQMYFINQMENDQQQSRKTDSTTIHVTQSPVVQQ 354 Query: 1399 EAKVL-ELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKES 1457 KVL E QLE K + + + T LTQ +VE + +E + E+ Sbjct: 355 RMKVLQERNLQLEEKLRQTNDQLNSQTAPLTQLQQNNSQNNTTIVELDSDLESSNSDDEA 414 Query: 1458 ELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVS-LNKQVAELNKALEEEV 1516 E + +L M E + + + E + + K IEE+ KI + + +N + +L + Sbjct: 415 E-KLSKLLMTERSEAEQRLADERD-QLKKQIEEMQNKIDKMQNDINDKDQQLTQ-FYSNY 471 Query: 1517 AKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTM 1576 N ++ + +E +I ++ +I ++ + S I S ++ +D+ N + Sbjct: 472 DDRNMLKDEIAKKENQIKEISKQIEEMKKLKENDKSDISTLKSL-NEELNTKDKDNQNNI 530 Query: 1577 NKELLDAVPRAELDL 1591 K+LL + +L L Sbjct: 531 -KKLLKKLKENDLKL 544 >UniRef50_A0C3N5 Cluster: Chromosome undetermined scaffold_147, whole genome shotgun sequence; n=3; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_147, whole genome shotgun sequence - Paramecium tetraurelia Length = 3822 Score = 158 bits (384), Expect = 1e-36 Identities = 288/1485 (19%), Positives = 623/1485 (41%), Gaps = 128/1485 (8%) Query: 156 NALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTK 215 N + L++ ++ E+ I Q+ I E+ + + ++ Sbjct: 283 NQSNQLEIILQQKESEISSFQQLIQEQKDKLTLIQQQYQDLEFLHLYEAQIIEKNNQELL 342 Query: 216 QQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLA 275 Q+ +Q+ + +E KD + + ++ + ++ IS L +LLE ++ L ++KL Sbjct: 343 NQIDNLQQQISNLTSELKDSEVKHIQVKQMQETTISKLNHDVRLLEQKNEDLILHNNKLI 402 Query: 276 QELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLN 335 E++Q + E + +IE+ E K++ ++E LN Sbjct: 403 NEIKQNELNQQKESTIICQKNSEFEIQLLESQHQIEDL-------KQEKQKQVHVVEMLN 455 Query: 336 CQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLN 395 Q+ Q + ++KL T+ + K I+ +++ + P ++ S+ LN Sbjct: 456 RQL-QVQVQAQSKLEEDITKYQNFLISHDKQLEAITSNESSDSSDSSEEPVTE-KSQQLN 513 Query: 396 QDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQL--- 452 D +I +++ ++ K + + + K T + + +L Sbjct: 514 FDALCNKLTEKIRLIQLRLEIYEKQIKQYKQELHSKTTEIQKLFSENSESNLKVQRLSQI 573 Query: 453 --QLEHQQHMEGPSLIHVGTNTEDVN-EIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAE 509 +LE+Q + SL E++ + K+Q Q K EI++ + +L ++K + Sbjct: 574 QPKLENQLENQEESLKQKDQTIENLTLQNTKLQIQFK-----EIEESKL-ELENQIKLLQ 627 Query: 510 EQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFS-KVSDSNKEIVRLTEELHHLS 568 E Q + +D N+ + + KS LK++++ + +NF ++ +S ++ +L E L+ Sbjct: 628 ED--QQSQSLDFQNQILAQAKS-QDLKIEELTRINNNFEIQLIESENKLKQLQIENESLN 684 Query: 569 QKVA----ELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKF 624 K+A EL + LQL LV + + + + ++ I+ NL+ +S+ + Q F Sbjct: 685 LKIASSDIELSNLQNQLQLELVIKNDLQSNLNSIKEEQIQNFNLSNGETTEVSVFD-QVF 743 Query: 625 DLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIEN 684 + +L +E+ +K+ + Q++ D + + + + + L +K + Sbjct: 744 PNINYQMVLFT--EELTEKIKNNLQIKMDSLDKNLLRI-INKYQKLLEKVQKNYHNIQNL 800 Query: 685 LKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQ 744 +L ++ L ++ KE + N++ +E + ++ ++ LL N E+Q Sbjct: 801 YELSQQTLIQQESAYQDQKEKLSNQINTLQEEINSKNSHIHQLEDQQKKLLLDLSNIEQQ 860 Query: 745 SK------IQTQFGID----AKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYS 794 ++ Q Q +D KI E + + N +SEL + ++ +LE+ + + + +S Sbjct: 861 NQDKQIIINQQQLKLDEIHKTKIVELEKIVTNQQSELEQILTKSNQLEQQVQDQKSQIHS 920 Query: 795 LERKADQLGSYL----------QEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEI 844 + + ++L L Q Q + + Q EL++ L + ++++L ++ Sbjct: 921 KQNRINELKQELNHLKNDQTGVQIDQLKFQQQQNQILELISNNTNLTQQNLDIQRRLKQV 980 Query: 845 EHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKA-----------NRTDLAESES 893 E N+ LQ K L ++ + + ++ +QQ + V+++ + D E+ Sbjct: 981 EDSNQALQDKINQLTKQGASQKEIINQLQQQNQSEVKQSLALMQQMDPLQKQIDFLTREN 1040 Query: 894 TKYQTQLRDLESNLKR--ITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYE 951 K Q D E + I VQ +I+ LE E QI+ +R +K + EK + Sbjct: 1041 RKLQQSNTDFEKAYGKLPIYGSPSPKKVQNNDQIKKLEDELQ-QIQ--LRFQKEMGEK-D 1096 Query: 952 KNIEYVT-QLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINE 1010 K I +++ Q E QLQ+ K ++N +E+NK+ I + +Q Q + + E Sbjct: 1097 KEINHISIQYEFQLQQQK------DLNQDEINKLEQNCITFSNELKQQQI--LNNKLLEE 1148 Query: 1011 INKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQ 1070 K+ Q E++ L Q++N + M + ES+L +F + +E Q++ K Sbjct: 1149 NGKVEREKLQLIEKVEKLTQQLNECSQN-QQMFAQQESELKRFIVLHQQALDENQKLQKL 1207 Query: 1071 LLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDX 1130 ++ ++ N+ L+ ++Q +L++ F+ + + +G N V+ Sbjct: 1208 FINLEEENKNLK---QQQSLLSTQLEQQYNEFQSEVKQQKG--------------NYVEQ 1250 Query: 1131 XXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDV 1190 E++ + LQ + N E Y K+I + + + D+ Sbjct: 1251 EHLHLEQIKTL-----EQKLCEINGELQNNQMQFN-NTNESYEKVIADKNEQLQNSKKDI 1304 Query: 1191 VNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQ-RGFEIAELWKQHLAQREAD 1249 Q+ Q+ + L+Q+N + NL + E I + +++ + E+ KQ Q++ D Sbjct: 1305 --QDLQKQINNSLDQIN-QFKNL---IEEKEQQIQNCINESKQIEVDYKNKQQSLQQQID 1358 Query: 1250 FQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQ-NKLQDKEEHLRN 1308 Q+ E + + + + + VQ S Q+ N I EQ+ S + N+ +D L+N Sbjct: 1359 DQQ-EQLQNSKNNVLDLQQQIANQDVQISQQK--NVIQQKEQLISNKINQSKDLNLELQN 1415 Query: 1309 LQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDL-RTENQSYKQMQEQSI 1367 EK +I+ + + +D + + E Q ++ E Sbjct: 1416 KLEKLQQLIDDLNLKLKNSQDNTLDLQQQINLQEDQINKQKNIIEEKEKQLQAKINESKQ 1475 Query: 1368 LNINEENAQ--LKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTI 1425 + IN N Q L+K V D + ++ Q+ + + I QK +I Sbjct: 1476 IEINNINKQQSLQKQIDDQQEQLQNSKNIVLDLQKQIANQEIQINQQKNVIQQKEQLISI 1535 Query: 1426 TLTQRNDEFENVRQQLVEYEKRIEDLTYEKESEL---AILRLKMH---ENANHYETMQKE 1479 + Q ND ++ +L ++ I+DL + ++ L L+ +++ + N Y+ + +E Sbjct: 1536 KINQSNDLNLELQNKLENLQQLIDDLNLQLKNSLDNNLDLQQQLNLQQDQINKYKNIIEE 1595 Query: 1480 SEIE-RVKLIEELNVK---ITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVT 1535 E E + K+ E ++ I + SL KQ+ + + L+ ++Q + NQ+++I Sbjct: 1596 KEKEIQAKINESKQIEVDYINKQYSLQKQIDDQQEQLQNSKNNILDLQKQVANQDVQINQ 1655 Query: 1536 LNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKEL 1580 N+ I + +++ ++ ++ K +QL + +N +L Sbjct: 1656 QNNVIQQKEELMQIKLNQ-SNDLNLQLQNKLENLQQLIDDLNSQL 1699 Score = 150 bits (364), Expect = 3e-34 Identities = 287/1471 (19%), Positives = 652/1471 (44%), Gaps = 120/1471 (8%) Query: 147 LSNTIKEKDNALSVLQVKMKIMETTILDLQEKIN-EKDQIIEAKNKATTXXXXXXXXXXX 205 L N ++ + L +++K LDLQ+++N ++DQI + KN Sbjct: 1547 LQNKLENLQQLIDDLNLQLKNSLDNNLDLQQQLNLQQDQINKYKNIIEEKEKEIQAKINE 1606 Query: 206 XXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLL---KDIESKDVRISSLEEANKLLEA 262 + +Q + +Q+ + + ++ K +L K + ++DV+I+ + E Sbjct: 1607 SKQIEVDYINKQYS-LQKQIDDQQEQLQNSKNNILDLQKQVANQDVQINQQNNVIQQKEE 1665 Query: 263 ARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMT 322 +I L S +L ++ S +++ L+ M Sbjct: 1666 L-MQIKLNQSN---DLNLQLQNKLENLQQLIDDLNSQLQTSKNNNQNLQQLKKLQEDQMN 1721 Query: 323 ELTKKIELLEH-LNCQIRQTNK-ELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTAS 380 + IE E+ L QI + K E++NK + +S + + ++R S + Sbjct: 1722 QYKNLIEEKENQLQIQINEQQKIEIDNKNTIENLQKLQISINNLQDLQKLTR-SQEDQIK 1780 Query: 381 KMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDK-EYVISEKDTXXXXXX 439 + K+ Q +E ++ K +KN QSL K + D E + + K+T Sbjct: 1781 QYKNLIDQKETEI---QSNIKESKNLEIDYNNKQQSLQKQIADSTEQLQNAKNTIQDLQK 1837 Query: 440 XXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTN-TEDVN-EIAKVQEQLKQELND---EIK 494 + + Q ++ HQ+ LI + N + ++N E+ QE L++ ++D ++K Sbjct: 1838 QIANQEIQINQQEKVIHQKE----ELISLKINQSNNLNLELQNKQEHLQEIIDDLSLQLK 1893 Query: 495 DV--NVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSD 552 + N L +++K E+QI + + I+ K + + K N KQM+ I+N +K Sbjct: 1894 NSQDNTLALQQQIKLKEDQIYKYQNIIEEKEKQL-QAKINES---KQME--INNINKQQS 1947 Query: 553 SNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETR 612 ++I E+L + + +L+++ N + + + +I+ I++ + Sbjct: 1948 LQQQIDDQQEQLQNSKCNILDLQKQVANQDVQISQQKN--VIQQKEQLISIKINQSNDLN 2005 Query: 613 LKAISLLESQKFDLVQELHI-LQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDAL 671 L+ + LE+ + L+ +L++ L+ D D I +LQ DQ+ + K++ +EE+ L Sbjct: 2006 LELQNKLENLQ-QLIVDLNLQLKNSQDNTLDLQQQI-KLQEDQIY-KYKNI-IEEKEKQL 2061 Query: 672 SASKKELALVIENLKLDKEQ-LYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAE 730 A E + +E ++K+Q L I D + ++ N +QN Q+ + D+++K + Sbjct: 2062 QAKINE-SKQMEINNINKQQSLQQQIDDQQEQLQNSKNNIQNLQQQLISQEDQIKKYHNQ 2120 Query: 731 -KISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVME 789 + +E+ ++ ++ + I ++ K+ + + I NI+ ++ +++I +E + Sbjct: 2121 IQENEIAYQVQNQNSNSINQT--LNQKLIDSENQILNIQKLINDEQNKI---QEQQKQFK 2175 Query: 790 DRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLL--EIEHE 847 + + +E +QL ++ + E +Q ++N + L++ +++ ++QL+ +++ + Sbjct: 2176 EEKEKVELVLEQLTLENKKSTQLVKEQEVQIS-MLNDIK-LVNENQLDQEQLINNQLKKD 2233 Query: 848 NKELQKK-NQILL-EENQNLQISL--SDMQQHYNAL-VEKANRTDLAESESTKYQTQLRD 902 N E ++K NQ+L+ EE+Q QIS S ++ + L K + + A+ + +Y+ +++ Sbjct: 2234 NLEKEQKINQLLIIEEDQKNQISKLNSQIKNEQDILNTLKIQQDEDAKYQIKEYEQIIKN 2293 Query: 903 LESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEA 962 L+ +K + + ++ I +++ E+++ +I+ + + I ++ L ++ EK +E ++ + Sbjct: 2294 LQVEVKEVANINKK-IFEQQIELDNNKIKL-IESQDKIHKQESLIKQLEKAVESNSE-SS 2350 Query: 963 QLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDY--TEQYINEINKLNALLKQ 1020 Q+ ++ E LN +++ ++ ++++ Q + + DY ++ + E+N + Sbjct: 2351 SFQKEQHQAE-LNFKQKQIEDKDIVILEQDTQIRNLKE-DYHNLQKQLQEMNHKIQTDQA 2408 Query: 1021 KDEEIIALNQ----KINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQ 1076 +EE L Q K+ + +++ + + + T + + +E + + +Q+ Sbjct: 2409 YNEESCRLFQTKLDKLESQNKDKENIIQQLQVQSQEITKQYDKSQELNEELKQQINGQSD 2468 Query: 1077 HNEELQILVREQDDQIKELKETKLTFEM-------NIPKTEGMI------ISSTIEPMSD 1123 + Q ++ +D+I +L T +T+E N K E I + + +SD Sbjct: 2469 QLNQKQQQIQSLEDKITQLSNTNITYEQKNTEFIQNFNKQEQQINELNNMVKVLTQEISD 2528 Query: 1124 DA----NNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLE 1179 N + L+ + +E I+ +++Q + Q+ + Q Sbjct: 2529 KEDKYKNEIVQQKKEYLSDKLSLENRIKESMIEWNQKVEDQRKHYENQHQDMENNLNQER 2588 Query: 1180 TLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELW 1239 L+ + ++ +I L+ LE+ + +N +LLS++ ELRS + +Q E + Sbjct: 2589 ILSKQFEENNKELSLRIQNLEMILEKHSQDNADLLSSIEELRSENHN--NQSELEKIKKD 2646 Query: 1240 KQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKL 1299 K+ L E +Q+ E++ + + +S E L + Q + KIV EQ +++Q ++ Sbjct: 2647 KEEL---EVKYQQMEYQKNESVDSNKSLQEMLFELKQIN-----EKIV--EQNSAIQREM 2696 Query: 1300 QDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFX----XXXXXXXXXXXXXXXDLRTE 1355 + + ++L+++Y+ +IN+ L ++ ++K A +R E Sbjct: 2697 GEIQSMNQSLEKRYSLLINEKSSLLEQVREQKSALADQCQQYIQLDSQFNQMQQNFIRIE 2756 Query: 1356 NQS-----YKQMQEQSILNINEENAQ-LKKSSXXXXXXXXXXXXRVNDAEAKVL------ 1403 +QS Q EQS+ + N Q ++K ++ D + +V Sbjct: 2757 SQSNSLKQINQQLEQSLQQQQQVNTQIIQKQEQQYQQQLDQLTLQLQDGQNQVRLLQQKN 2816 Query: 1404 -ELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAIL 1462 E ++++ ++ Q + + Q E E Q+L++ ++E L + ++E IL Sbjct: 2817 GEQRQEIQMIRNDQKQWENNKVNEMVQMKQESERQIQKLMDQVSQVEGLNKQYQNE--IL 2874 Query: 1463 RLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNE- 1521 L N + +K+ +++E+L K+ S +++ N+AL EE A E Sbjct: 2875 EL---NNIIKKQFEEKDKSSVNNQVVEQLQTKLKLSEEQIERLLMTNRALMEENANLQEQ 2931 Query: 1522 MQTALENQEIEIVTLNDEITNLQNMVRASSS 1552 ++ L + + N N +N V S+ Sbjct: 2932 IKDDLNSSFCSNASQNCATKNQENEVSLPSN 2962 Score = 147 bits (355), Expect = 3e-33 Identities = 270/1529 (17%), Positives = 641/1529 (41%), Gaps = 89/1529 (5%) Query: 93 SLANTLKQKEILMEKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIK 152 +L + LK E+ ++KQ +E + VR + ++ N + Sbjct: 354 NLTSELKDSEVKHIQVKQMQETTISKLNHDVRLLEQKNEDLILHNNKLINEIKQ--NELN 411 Query: 153 EKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXE 212 ++ + + Q K E +L+ Q +I + Q + + E Sbjct: 412 QQKESTIICQ-KNSEFEIQLLESQHQIEDLKQEKQKQVHVVEMLNRQLQVQVQAQSKLEE 470 Query: 213 DTKQQMTKMQENFIAMEA----EWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEIS 268 D + + + +EA E D + + K +++ NKL E R I Sbjct: 471 DITKYQNFLISHDKQLEAITSNESSDSSDSSEEPVTEKSQQLNFDALCNKLTEKIRL-IQ 529 Query: 269 LEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEK--TEIEEKGSLEIANMTE-LT 325 L ++++Q L ++ E + + + ++I+ K ++ N E L Sbjct: 530 LRLEIYEKQIKQYKQELHSKTTEIQKLFSENSESNLKVQRLSQIQPKLENQLENQEESLK 589 Query: 326 KKIELLEHL---NCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKM 382 +K + +E+L N +++ KE+E + + K + + S L + A Sbjct: 590 QKDQTIENLTLQNTKLQIQFKEIEESKLELENQIKLLQEDQQSQS-LDFQNQILAQAKSQ 648 Query: 383 KSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXX 442 +L+ N + ++N++ +L++ +SLN + + +S Sbjct: 649 DLKIEELTRINNNFEIQLIESENKLKQLQIENESLNLKIASSDIELSNLQNQLQLELVI- 707 Query: 443 XGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLI 502 K+ L + L ++ ++ +L + G TE V +Q+ +N ++ + ++L Sbjct: 708 --KNDLQSNLNSIKEEQIQNFNLSN-GETTE-----VSVFDQVFPNINYQMV-LFTEELT 758 Query: 503 EKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTE 562 EK+K+ L ++D+ +KN++++ + ++ L+++QK N + + +++ + + + Sbjct: 759 EKIKN------NLQIKMDSLDKNLLRIINKYQKLLEKVQKNYHNIQNLYELSQQTL-IQQ 811 Query: 563 ELHHLSQKVAELEEEKGNLQLHLVDYDSG-RMIESDVYKKMIEMENLAETRLKAISLLES 621 E + QK +L + LQ + +S +E K ++++ N+ + ++ Sbjct: 812 ESAYQDQK-EKLSNQINTLQEEINSKNSHIHQLEDQQKKLLLDLSNIEQQNQDKQIIINQ 870 Query: 622 QKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALV 681 Q+ L E+H + K E+E K+ Q + +Q+ + KS LE+Q+ + Sbjct: 871 QQLKL-DEIH--KTKIVELE-KIVTNQQSELEQILT--KSNQLEQQVQDQKSQIHSKQNR 924 Query: 682 IENLKLDKEQLYGTIKDLENDK---EDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAK 738 I LK + L ++ D+ + N++ I N +LT + + ++ + + Sbjct: 925 INELKQELNHLKNDQTGVQIDQLKFQQQQNQILELISNNTNLTQ--QNLDIQRRLKQVED 982 Query: 739 INHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERK 798 N Q KI A ++++ + + S+ K + +++ + + + L R+ Sbjct: 983 SNQALQDKINQLTKQGAS--QKEIINQLQQQNQSEVKQSLALMQQMDPLQKQIDF-LTRE 1039 Query: 799 ADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHE-NKELQKKNQI 857 +L + +KAY + I ++ D + +E +L +I+ KE+ +K++ Sbjct: 1040 NRKLQQSNTDFEKAYGKLPIYGSPSPKKVQN-NDQIKKLEDELQQIQLRFQKEMGEKDKE 1098 Query: 858 LLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRD--LESNLKRITHEHQ 915 + + + L + + K + + S K Q L + LE N K + E Sbjct: 1099 INHISIQYEFQLQQQKDLNQDEINKLEQNCITFSNELKQQQILNNKLLEENGK-VEREKL 1157 Query: 916 TLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLN 975 LI + +K + L Q A ++ ++ +++ + +LQ+ N+E N Sbjct: 1158 QLIEKVEKLTQQLNECSQNQQMFAQQESEL--KRFIVLHQQALDENQKLQKLFINLEEEN 1215 Query: 976 MNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNA 1035 N+++ + +++ + Q++ Y+ + + +K ++++ +N ++ N Sbjct: 1216 KNLKQQQSLLSTQLEQQYNEFQSEVKQQKGNYVEQEHLHLEQIKTLEQKLCEINGELQNN 1275 Query: 1036 QVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIK-- 1093 Q+ + + YE +A +L+N ++++Q + KQ+ +S + + L+ E++ QI+ Sbjct: 1276 QMQFNNTNESYEKVIADKNEQLQNSKKDIQDLQKQINNSLDQINQFKNLIEEKEQQIQNC 1335 Query: 1094 --ELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFI 1151 E K+ ++ ++ N ++ I E + + NNV +++ +++ I Sbjct: 1336 INESKQIEVDYK-NKQQSLQQQIDDQQEQLQNSKNNV--LDLQQQIANQDVQISQQKNVI 1392 Query: 1152 QERSVL----QEQSAKLNTELQECYTKIIQL-ETLNTELTGHDVVNQEQINQLKSKLEQL 1206 Q++ L QS LN ELQ K+ QL + LN +L + Q+ + +Q+ Sbjct: 1393 QQKEQLISNKINQSKDLNLELQNKLEKLQQLIDDLNLKLKNSQDNTLDLQQQINLQEDQI 1452 Query: 1207 NTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFES 1266 N + + + +L++ I+ + + EI + KQ Q++ D Q + +L+ + Sbjct: 1453 NKQKNIIEEKEKQLQAKIN---ESKQIEINNINKQQSLQKQIDDQ--QEQLQNSKNIVLD 1507 Query: 1267 KYEQLLDSVQSSTQEETNKIVTMEQVTSLQ-NKLQDKEEHLRNLQEKYADVINQIEI-LR 1324 +Q+ + + ++ N I EQ+ S++ N+ D L+N E +I+ + + L+ Sbjct: 1508 LQKQIANQ-EIQINQQKNVIQQKEQLISIKINQSNDLNLELQNKLENLQQLIDDLNLQLK 1566 Query: 1325 SEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQ--LKKSSX 1382 + +++ E + ++ E + ++ N Q L+K Sbjct: 1567 NSLDNNLDLQQQLNLQQDQINKYKNIIEEKEKEIQAKINESKQIEVDYINKQYSLQKQID 1626 Query: 1383 XXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLV 1442 + D + +V Q+ +++ I QK I L Q ND ++ +L Sbjct: 1627 DQQEQLQNSKNNILDLQKQVANQDVQINQQNNVIQQKEELMQIKLNQSNDLNLQLQNKLE 1686 Query: 1443 EYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLN 1502 ++ I+DL + ++ ++N + +Q++ + LIEE ++ ++ Sbjct: 1687 NLQQLIDDLNSQLQTS-----KNNNQNLQQLKKLQEDQMNQYKNLIEEKENQLQIQINEQ 1741 Query: 1503 KQVAELNKALEEEVAKTNEMQTALEN-QEIEIVTLN--DEITNLQNMVRASSSKIQKHVS 1559 +++ NK E + K +Q ++ N Q+++ +T + D+I +N++ ++IQ ++ Sbjct: 1742 QKIEIDNKNTIENLQK---LQISINNLQDLQKLTRSQEDQIKQYKNLIDQKETEIQSNIK 1798 Query: 1560 FASDTKQGRDEQLDNTMNKELLDAVPRAE 1588 + + + + + ++ K++ D+ + + Sbjct: 1799 ESKNLEIDYNNK-QQSLQKQIADSTEQLQ 1826 Score = 143 bits (346), Expect = 4e-32 Identities = 304/1570 (19%), Positives = 681/1570 (43%), Gaps = 180/1570 (11%) Query: 147 LSNTIKEKDNALSVLQVKMKIMETTILDLQEKIN-EKDQIIEAKNKATTXXXXXXXXXXX 205 L N +++ + L +K+K + LDLQ++IN ++DQI + KN Sbjct: 1413 LQNKLEKLQQLIDDLNLKLKNSQDNTLDLQQQINLQEDQINKQKNIIEEKEKQLQAKINE 1472 Query: 206 XXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLL---KDIESKDVRISS----LEEANK 258 + +Q + +Q+ + + ++ K +L K I +++++I+ +++ + Sbjct: 1473 SKQIEINNINKQQS-LQKQIDDQQEQLQNSKNIVLDLQKQIANQEIQINQQKNVIQQKEQ 1531 Query: 259 LLEAA-------RFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQ---SIEPSCEEKT 308 L+ E+ + L Q ++ L +Q + + K Sbjct: 1532 LISIKINQSNDLNLELQNKLENLQQLIDDLNLQLKNSLDNNLDLQQQLNLQQDQINKYKN 1591 Query: 309 EIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSP 368 IEEK A + E +K+IE+ +++N Q K+++++ + + K+ + Sbjct: 1592 IIEEKEKEIQAKINE-SKQIEV-DYINKQY-SLQKQIDDQQEQLQNSKNNILDLQKQVAN 1648 Query: 369 LISRKSGRNTASKMKSPWSQLSSETLNQDTDKKIN-KNEIAKLEMVIQSLNKDLVDKEYV 427 + + +N + K Q+ LNQ D + +N++ L+ +I LN L + Sbjct: 1649 QDVQINQQNNVIQQKEELMQIK---LNQSNDLNLQLQNKLENLQQLIDDLNSQLQTSKNN 1705 Query: 428 ISEKDTXXXXXXXXXXGKDTLIA------QLQLEHQQHME--------GPSLIHVGTNT- 472 LI Q+Q+ QQ +E + + N Sbjct: 1706 NQNLQQLKKLQEDQMNQYKNLIEEKENQLQIQINEQQKIEIDNKNTIENLQKLQISINNL 1765 Query: 473 EDVNEIAKVQE-QLKQ----------ELNDEIKDV-NVK-DLIEKLKSAEEQITQLNDEI 519 +D+ ++ + QE Q+KQ E+ IK+ N++ D K +S ++QI +++ Sbjct: 1766 QDLQKLTRSQEDQIKQYKNLIDQKETEIQSNIKESKNLEIDYNNKQQSLQKQIADSTEQL 1825 Query: 520 DAAN---KNMIKVKSNHKLKLKQMQKTIDNFS-----KVSDSNKEIVRLTEELHHLSQKV 571 A +++ K +N ++++ Q +K I K++ SN + L + HL + + Sbjct: 1826 QNAKNTIQDLQKQIANQEIQINQQEKVIHQKEELISLKINQSNNLNLELQNKQEHLQEII 1885 Query: 572 AELEEEKGNLQLHLVDYDSG-RMIESDVYKKMIEMENLAETRLKAISLLESQKFDL--VQ 628 +L + N Q + + ++ E +YK +E E +L+A + ES++ ++ + Sbjct: 1886 DDLSLQLKNSQDNTLALQQQIKLKEDQIYKYQNIIEE-KEKQLQA-KINESKQMEINNIN 1943 Query: 629 ELHILQQKYDEVEDKL----ADISQLQSD------QVCSEIKSVHLEEQIDALSASKK-E 677 + LQQ+ D+ +++L +I LQ Q+ + + +EQ+ ++ ++ + Sbjct: 1944 KQQSLQQQIDDQQEQLQNSKCNILDLQKQVANQDVQISQQKNVIQQKEQLISIKINQSND 2003 Query: 678 LALVIENLKLDKEQLYGTIK-DLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELL 736 L L ++N + +QL + L+N +++ ++ LQ I+ D K + + EK +L Sbjct: 2004 LNLELQNKLENLQQLIVDLNLQLKNSQDNTLD-LQQQIKLQEDQIYKYKNIIEEKEKQLQ 2062 Query: 737 AKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMED--RRYS 794 AKIN +Q +I I+ K Q I++ + +L K+ I L++ + ED ++Y Sbjct: 2063 AKINESKQMEINN---IN-KQQSLQQQIDDQQEQLQNSKNNIQNLQQQLISQEDQIKKYH 2118 Query: 795 LERKADQLGSYLQEKQKAYSEYTIQ------EDELVNRLAVLMDHDRVVEKQLLEIEHEN 848 + + +++ +Q + T+ E++++N ++ D +++Q + + E Sbjct: 2119 NQIQENEIAYQVQNQNSNSINQTLNQKLIDSENQILNIQKLINDEQNKIQEQQKQFKEEK 2178 Query: 849 KELQKK-NQILLEENQNLQISLSDMQQHYNAL--VEKANRTDLAESESTKYQTQLRDLES 905 ++++ Q+ LE ++ Q+ + + + + L ++ N L + + Q + +LE Sbjct: 2179 EKVELVLEQLTLENKKSTQL-VKEQEVQISMLNDIKLVNENQLDQEQLINNQLKKDNLEK 2237 Query: 906 NLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQ 965 K +Q LI+++ ++ + ++ N+QI++ ++ +LN I+ + Q++ Sbjct: 2238 EQKI----NQLLIIEEDQKNQISKL--NSQIKN---EQDILNTL---KIQQDEDAKYQIK 2285 Query: 966 EYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDE-- 1023 EY+ I+NL + V+E+ +N ++ ++ ++ + Q ++I+K +L+KQ ++ Sbjct: 2286 EYEQIIKNLQVEVKEVANINKKIFEQQIELDNNKIKLIESQ--DKIHKQESLIKQLEKAV 2343 Query: 1024 ----EIIALNQKINNAQVSY-MSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHN 1078 E + ++ + A++++ + D + + + T++ N++E+ + KQL ++ N Sbjct: 2344 ESNSESSSFQKEQHQAELNFKQKQIEDKDIVILEQDTQIRNLKEDYHNLQKQL---QEMN 2400 Query: 1079 EELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXX 1138 ++Q ++ + L +TKL + K + II + D Sbjct: 2401 HKIQTDQAYNEESCR-LFQTKLDKLESQNKDKENIIQQLQVQSQEITKQYD--------- 2450 Query: 1139 XXXLKVQE-EEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQIN 1197 K QE EE Q+ + +Q + ++Q KI QL NT +T ++ N E I Sbjct: 2451 ----KSQELNEELKQQINGQSDQLNQKQQQIQSLEDKITQLS--NTNIT-YEQKNTEFIQ 2503 Query: 1198 QLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHEL 1257 + +Q+N N+ V L IS D+ EI + K++L+ D E+ + Sbjct: 2504 NFNKQEQQINELNN----MVKVLTQEISDKEDKYKNEIVQQKKEYLS----DKLSLENRI 2555 Query: 1258 RVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLR--NLQ---EK 1312 + + + K E ++ Q+ N + E++ S Q + +KE LR NL+ EK Sbjct: 2556 KESMIEWNQKVEDQRKHYENQHQDMENNL-NQERILSKQFEENNKELSLRIQNLEMILEK 2614 Query: 1313 Y----ADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSY---KQMQEQ 1365 + AD+++ IE LRSE + + +N+S K +QE Sbjct: 2615 HSQDNADLLSSIEELRSENHNNQSELEKIKKDKEELEVKYQQMEYQKNESVDSNKSLQEM 2674 Query: 1366 --SILNINE----ENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQK 1419 + INE +N+ +++ R + + L Q+ + S + + Sbjct: 2675 LFELKQINEKIVEQNSAIQREMGEIQSMNQSLEKRYSLLINEKSSLLEQVREQKSALADQ 2734 Query: 1420 THEYTITLTQRND------EFENVRQQLVEYEKRIED-LTYEKESELAILRLKMHENANH 1472 +Y +Q N E+ L + +++E L +++ I++ + + Sbjct: 2735 CQQYIQLDSQFNQMQQNFIRIESQSNSLKQINQQLEQSLQQQQQVNTQIIQKQEQQYQQQ 2794 Query: 1473 YE--TMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQE 1530 + T+Q + +V+L+++ N + + + + + N + E K NEM + E Sbjct: 2795 LDQLTLQLQDGQNQVRLLQQKNGEQRQEIQMIR-----NDQKQWENNKVNEMVQMKQESE 2849 Query: 1531 IEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDE-QLDNTMNKELLDAVPRAEL 1589 +I L D+++ ++ + + ++I + + + +D+ ++N + ++L + +E Sbjct: 2850 RQIQKLMDQVSQVEGLNKQYQNEILELNNIIKKQFEEKDKSSVNNQVVEQLQTKLKLSEE 2909 Query: 1590 DLAMYMLHQR 1599 + ++ R Sbjct: 2910 QIERLLMTNR 2919 Score = 136 bits (330), Expect = 4e-30 Identities = 292/1479 (19%), Positives = 635/1479 (42%), Gaps = 183/1479 (12%) Query: 216 QQMTKMQEN----FIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271 QQM QE+ FI + + DE Q+L K + + +L++ LL ++ ++ Sbjct: 1177 QQMFAQQESELKRFIVLHQQALDENQKLQKLFINLEEENKNLKQQQSLLST---QLEQQY 1233 Query: 272 SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKI--- 328 ++ E++Q K + CE E++ ++ N E +K+ Sbjct: 1234 NEFQSEVKQQKGNYVEQEHLHLEQIKTLEQKLCEINGELQNN-QMQFNNTNESYEKVIAD 1292 Query: 329 --ELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLI--SRKSGRNTASKMKS 384 E L++ I+ K++ N L + + ++ I S++ + +K +S Sbjct: 1293 KNEQLQNSKKDIQDLQKQINNSLDQINQFKNLIEEKEQQIQNCINESKQIEVDYKNKQQS 1352 Query: 385 PWSQLSS--ETLNQDTDKKIN-KNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXX 441 Q+ E L + ++ + +IA ++ I + KE +IS K Sbjct: 1353 LQQQIDDQQEQLQNSKNNVLDLQQQIANQDVQISQQKNVIQQKEQLISNKINQSKDLNLE 1412 Query: 442 XXGK----DTLIAQLQLEHQQHMEGPSLIHVGTNTED------VNEIAKVQEQLKQELND 491 K LI L L+ + + + N ++ N I + ++QL+ ++N Sbjct: 1413 LQNKLEKLQQLIDDLNLKLKNSQDNTLDLQQQINLQEDQINKQKNIIEEKEKQLQAKIN- 1471 Query: 492 EIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMI----KVKSNHKLKLKQMQKTIDNF 547 E K + + + I K +S ++QI +++ + KN++ K +N ++++ Q + I Sbjct: 1472 ESKQIEINN-INKQQSLQKQIDDQQEQLQNS-KNIVLDLQKQIANQEIQINQQKNVIQQK 1529 Query: 548 S-----KVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDV---Y 599 K++ SN + L +L +L Q + +L + N + +D ++ D Y Sbjct: 1530 EQLISIKINQSNDLNLELQNKLENLQQLIDDLNLQLKNSLDNNLDLQQQLNLQQDQINKY 1589 Query: 600 KKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLAD----ISQLQSDQV 655 K +IE E E + K I+ + + D + + + LQ++ D+ +++L + I LQ QV Sbjct: 1590 KNIIE-EKEKEIQAK-INESKQIEVDYINKQYSLQKQIDDQQEQLQNSKNNILDLQK-QV 1646 Query: 656 CSEIKSVHLEEQIDALSASKKELALVIE-----NLKLDK--EQLYGTIKDLENDKEDIMN 708 ++ V + +Q + + ++ + + + NL+L E L I DL + + N Sbjct: 1647 ANQ--DVQINQQNNVIQQKEELMQIKLNQSNDLNLQLQNKLENLQQLIDDLNSQLQTSKN 1704 Query: 709 KLQNYIQENM---DLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIE 765 QN Q D ++ + + EK ++L +IN +++ +I + I+ +Q+ + I Sbjct: 1705 NNQNLQQLKKLQEDQMNQYKNLIEEKENQLQIQINEQQKIEIDNKNTIE-NLQKLQISIN 1763 Query: 766 NI----------ESELSKYKSRICRLEESIA--VMEDRRYSLE--RKADQLGSYLQE--K 809 N+ E ++ +YK+ I + E I + E + ++ K L + + + Sbjct: 1764 NLQDLQKLTRSQEDQIKQYKNLIDQKETEIQSNIKESKNLEIDYNNKQQSLQKQIADSTE 1823 Query: 810 QKAYSEYTIQE--DELVNRLAVLMDHDRVVEKQ----LLEIEHENK---ELQKKNQILLE 860 Q ++ TIQ+ ++ N+ + ++V+ ++ L+I N ELQ K + L E Sbjct: 1824 QLQNAKNTIQDLQKQIANQEIQINQQEKVIHQKEELISLKINQSNNLNLELQNKQEHLQE 1883 Query: 861 ENQNLQISLSDMQ------------------QHYNALVEKANRTDLAESESTKYQTQLRD 902 +L + L + Q ++ N + EK + +ES + + + Sbjct: 1884 IIDDLSLQLKNSQDNTLALQQQIKLKEDQIYKYQNIIEEKEKQLQAKINESKQMEINNIN 1943 Query: 903 LESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEA 962 + +L++ + Q + K I DL+ + Q + K V+ +K + + Q Sbjct: 1944 KQQSLQQQIDDQQEQLQNSKCNILDLQKQVANQDVQISQQKNVIQQKEQLISIKINQSND 2003 Query: 963 QLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKD 1022 E +N +ENL + +L NL+L K+ Q + ++I K ++++K+ Sbjct: 2004 LNLELQNKLENLQQLIVDL---NLQL--KNSQDNTLDLQQQIKLQEDQIYKYKNIIEEKE 2058 Query: 1023 EEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQ 1082 ++ L KIN ++ ++ ++ K +++++++ +QL +SK + + LQ Sbjct: 2059 KQ---LQAKINESKQMEINNIN-----------KQQSLQQQIDDQQEQLQNSKNNIQNLQ 2104 Query: 1083 ILVREQDDQIK----ELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXX 1138 + Q+DQIK +++E ++ +++ + I+ T+ D+ N Sbjct: 2105 QQLISQEDQIKKYHNQIQENEIAYQVQNQNSNS--INQTLNQKLIDSEN-QILNIQKLIN 2161 Query: 1139 XXXLKVQEEE-EFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQIN 1197 K+QE++ +F +E+ ++ +L E ++ + + E + L +VN+ Q++ Sbjct: 2162 DEQNKIQEQQKQFKEEKEKVELVLEQLTLENKKSTQLVKEQEVQISMLNDIKLVNENQLD 2221 Query: 1198 QLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHEL 1257 Q + QL +N L ++ + DQ+ +I++L Q + E D T L Sbjct: 2222 QEQLINNQLKKDN---LEKEQKINQLLIIEEDQKN-QISKLNSQ--IKNEQDILNT---L 2272 Query: 1258 RVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVI 1317 ++Q ++KY+ ++ Q N V +++V ++ K+ +++ L N + K + Sbjct: 2273 KIQQDE-DAKYQ-----IKEYEQIIKNLQVEVKEVANINKKIFEQQIELDNNKIKLIESQ 2326 Query: 1318 NQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQL 1377 ++I S I+ + A +L N KQ++++ I+ I E++ Q+ Sbjct: 2327 DKIHKQESLIKQLEKAVESNSESSSFQKEQHQAEL---NFKQKQIEDKDIV-ILEQDTQI 2382 Query: 1378 KKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQ---RNDEF 1434 + ++ + ++ E+ H+++ + + + L + +N + Sbjct: 2383 RNLKED-----------YHNLQKQLQEMNHKIQTDQAYNEESCRLFQTKLDKLESQNKDK 2431 Query: 1435 ENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEI----ERVKLIEE 1490 EN+ QQL + I Y+K EL LK N + QK+ +I +++ + Sbjct: 2432 ENIIQQLQVQSQEITK-QYDKSQELN-EELKQQINGQSDQLNQKQQQIQSLEDKITQLSN 2489 Query: 1491 LNV----KITESV-SLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVT-----LNDEI 1540 N+ K TE + + NKQ ++N+ T E+ + + EIV L+D++ Sbjct: 2490 TNITYEQKNTEFIQNFNKQEQQINELNNMVKVLTQEISDKEDKYKNEIVQQKKEYLSDKL 2549 Query: 1541 TNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKE 1579 +L+N ++ S + + V + + + ++N +N+E Sbjct: 2550 -SLENRIKESMIEWNQKVEDQRKHYENQHQDMENNLNQE 2587 Score = 126 bits (305), Expect = 4e-27 Identities = 217/1093 (19%), Positives = 456/1093 (41%), Gaps = 88/1093 (8%) Query: 144 VTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXX 203 + LS +K + LQ ++K+ E I Q I EK++ ++AK + Sbjct: 1885 IDDLSLQLKNSQDNTLALQQQIKLKEDQIYKYQNIIEEKEKQLQAKINESKQMEINNINK 1944 Query: 204 XXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKD---IESKDVRIS-SLEEANKL 259 +D ++Q+ + N + ++ + ++ ++ + I+ K+ IS + ++N L Sbjct: 1945 QQSLQQQIDDQQEQLQNSKCNILDLQKQVANQDVQISQQKNVIQQKEQLISIKINQSNDL 2004 Query: 260 LEAARFEISLEH-SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEI 318 + LE+ +L +L K + + K IEEK Sbjct: 2005 --NLELQNKLENLQQLIVDLNLQLKNSQDNTLDLQQQIKLQEDQIYKYKNIIEEKEKQLQ 2062 Query: 319 ANMTELTKKIEL-----LEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRK 373 A + E +K++E+ + L QI ++L+N + + + S + ++ Sbjct: 2063 AKINE-SKQMEINNINKQQSLQQQIDDQQEQLQNSKNNIQNLQQQLISQEDQIKKYHNQI 2121 Query: 374 SGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDT 433 A ++++ S ++TLNQ ++N+I ++ +I + +++ E+ Sbjct: 2122 QENEIAYQVQNQNSNSINQTLNQKLID--SENQILNIQKLINDEQNKIQEQQKQFKEEKE 2179 Query: 434 XXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEI 493 ++ QL E + + + I + N +++ + QLK++ ++ Sbjct: 2180 KVELVLEQLTLENKKSTQLVKEQEVQISMLNDIKL-VNENQLDQEQLINNQLKKDNLEKE 2238 Query: 494 KDVNVKDLIEKLKSAEEQITQLNDEI----DAANKNMIKVKSNHKLKLKQMQKTIDNF-- 547 + +N +IE + + QI++LN +I D N I+ + K ++K+ ++ I N Sbjct: 2239 QKINQLLIIE--EDQKNQISKLNSQIKNEQDILNTLKIQQDEDAKYQIKEYEQIIKNLQV 2296 Query: 548 --SKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEM 605 +V++ NK+I EL + K+ E ++K + Q L+ + +ES+ + Sbjct: 2297 EVKEVANINKKIFEQQIELDNNKIKLIE-SQDKIHKQESLIK-QLEKAVESNSESSSFQK 2354 Query: 606 E-NLAETRLKAISLLESQKFDLVQELHI--LQQKYDEVEDKLADIS-QLQSDQVCSEIKS 661 E + AE K + + L Q+ I L++ Y ++ +L +++ ++Q+DQ +E Sbjct: 2355 EQHQAELNFKQKQIEDKDIVILEQDTQIRNLKEDYHNLQKQLQEMNHKIQTDQAYNEESC 2414 Query: 662 VHLEEQIDALSASKKELALVIENLKL---------DKEQ-LYGTIKDLENDKEDIMNKLQ 711 + ++D L + K+ +I+ L++ DK Q L +K N + D +N+ Q Sbjct: 2415 RLFQTKLDKLESQNKDKENIIQQLQVQSQEITKQYDKSQELNEELKQQINGQSDQLNQKQ 2474 Query: 712 NYIQENMDLTDKLEKMS---AEKISELLAKINHEEQS--------KIQTQFGIDAKIQER 760 IQ D +L + +K +E + N +EQ K+ TQ D + + + Sbjct: 2475 QQIQSLEDKITQLSNTNITYEQKNTEFIQNFNKQEQQINELNNMVKVLTQEISDKEDKYK 2534 Query: 761 DLYIENIESELSKYKSRICRLEESI----AVMEDRRYSLERKADQLGSYLQEKQKAYSEY 816 + ++ + LS S R++ES+ +ED+R E + + + L +++ ++ Sbjct: 2535 NEIVQQKKEYLSDKLSLENRIKESMIEWNQKVEDQRKHYENQHQDMENNLNQERILSKQF 2594 Query: 817 TIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHY 876 EL R+ L + ++EK +N +L + L EN N Q L +++ Sbjct: 2595 EENNKELSLRIQNL---EMILEKH----SQDNADLLSSIEELRSENHNNQSELEKIKKDK 2647 Query: 877 NALVEKANRTDLAESESTKYQTQLRDLESNLKRITH---EHQTLIVQKKKEIEDLEIEFN 933 L K + + ++ES L+++ LK+I E + I ++ EI+ + Sbjct: 2648 EELEVKYQQMEYQKNESVDSNKSLQEMLFELKQINEKIVEQNSAIQREMGEIQSMNQSLE 2707 Query: 934 TQIESAIRDKKVLNEKYEK-------NIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNL 986 + I +K L E+ + + QL++Q + + N + L ++N Sbjct: 2708 KRYSLLINEKSSLLEQVREQKSALADQCQQYIQLDSQFNQMQQNFIRIESQSNSLKQINQ 2767 Query: 987 ELIDKHVQKQQTQS---PDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMV 1043 +L Q+QQ + +QY ++++L L+ ++ L QK N Q + M+ Sbjct: 2768 QLEQSLQQQQQVNTQIIQKQEQQYQQQLDQLTLQLQDGQNQVRLLQQK-NGEQRQEIQMI 2826 Query: 1044 -SDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKE-TKLT 1101 +D + ++ M++E +R ++L+D E L ++ ++I EL K Sbjct: 2827 RNDQKQWENNKVNEMVQMKQESERQIQKLMDQVSQVEGLN---KQYQNEILELNNIIKKQ 2883 Query: 1102 FEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQS 1161 FE K + + + +E + + L EE +QE+ S Sbjct: 2884 FE---EKDKSSVNNQVVEQLQTKLKLSEEQIERLLMTNRAL--MEENANLQEQIKDDLNS 2938 Query: 1162 AKLNTELQECYTK 1174 + + Q C TK Sbjct: 2939 SFCSNASQNCATK 2951 Score = 113 bits (271), Expect = 5e-23 Identities = 207/1086 (19%), Positives = 467/1086 (43%), Gaps = 106/1086 (9%) Query: 493 IKDVNVKD--LIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKV 550 +K VN LI+KL +E I LN+EI+A+N+ + ++S H L L Q I++ Sbjct: 10 LKQVNKNQTLLIQKL---QEDIQVLNEEIEASNQQIDTLRSEHHLALSQQLSLIEDLRNE 66 Query: 551 SDS----NKEI-VRLTEELHHLSQKVAELEEEKGNLQ--------------LHLVDYDSG 591 S + N E+ + T+ + L ++ + + +K N Q +HL + D Sbjct: 67 SQNYQQQNMELQTKFTQSV--LQNQLLQTKYDKKNKQYKDQIIELKQQIKLIHLKNQDYQ 124 Query: 592 RMIESDVYKKMIEMENLAETRLK-AISLLESQKFDLVQELHILQQKYDEVEDKLADISQL 650 R I +K ++++ L ++ S+L Q L L + + Y+ +++ ++ Q Sbjct: 125 REIID--LRKSLDVKKLELSKFNDNSSILNEQNNQLKANLDLQKVDYENKIEQIQNLIQD 182 Query: 651 QSDQVCSEIKSVHL-----EEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKED 705 + +++ + L E I+A + + L I L+ + L + DL N+ Sbjct: 183 KDEEITLILNDNKLLNKTNLELIEANANQSQTLQSQINTLEQHNQTLQIQLSDLLNENNL 242 Query: 706 IMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIE 765 + + Q QE + ++ SA + + + ++ + Q ++ +Q+++ I Sbjct: 243 LKQQFQQQTQEMQVIPSSIQLQSAAESQQEMVQLQNSNLLNQSNQ--LEIILQQKESEIS 300 Query: 766 NIESELSKYKSRICRLEESIAVME----DRRYSLERKADQLGSYLQEKQKAYSEYTIQ-E 820 + + + + K ++ +++ +E +E+ +L + + Q+ S T + + Sbjct: 301 SFQQLIQEQKDKLTLIQQQYQDLEFLHLYEAQIIEKNNQELLNQIDNLQQQISNLTSELK 360 Query: 821 DELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALV 880 D V + V + + K + H+ + L++KN+ L+ N L +++++Q N L Sbjct: 361 DSEVKHIQVKQMQETTISK----LNHDVRLLEQKNEDLILHNNKL---INEIKQ--NELN 411 Query: 881 EKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAI 940 ++ T + + S +++ QL LES H+ + L +K+K++ +E+ N Q++ + Sbjct: 412 QQKESTIICQKNS-EFEIQL--LESQ-----HQIEDLKQEKQKQVHVVEM-LNRQLQVQV 462 Query: 941 RDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMN------VEELNKMNLELIDKHVQ 994 + + L E K ++ + QL+ +N + + + E+ ++N + + + Sbjct: 463 QAQSKLEEDITKYQNFLISHDKQLEAITSNESSDSSDSSEEPVTEKSQQLNFDALCNKLT 522 Query: 995 KQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFT 1054 ++ E Y +I + L K EI L + + + + + +S + KL Sbjct: 523 EKIRLIQLRLEIYEKQIKQYKQELHSKTTEIQKLFSENSESNLK-VQRLSQIQPKL---E 578 Query: 1055 TKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMII 1114 +LEN EE +++ + + + N +LQI Q KE++E+KL E I + Sbjct: 579 NQLENQEESLKQKDQTIENLTLQNTKLQI-------QFKEIEESKLELENQIKLLQEDQQ 631 Query: 1115 SSTIEPMSD---DANNVDXXXXXXXXXXXXLKVQ--EEEEFIQERSVLQEQSAKLNTELQ 1169 S +++ + A + D ++Q E E +++ LQ ++ LN ++ Sbjct: 632 SQSLDFQNQILAQAKSQDLKIEELTRINNNFEIQLIESENKLKQ---LQIENESLNLKIA 688 Query: 1170 ECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVD 1229 + I+L L +L V+ + + L S +++ +N NL + S Sbjct: 689 ---SSDIELSNLQNQLQLELVIKNDLQSNLNS-IKEEQIQNFNLSNGETTEVSVFDQVFP 744 Query: 1230 QRGFEIAELWKQHLAQR-EADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVT 1288 +++ L+ + L ++ + + Q L L +KY++LL+ VQ + N + Sbjct: 745 NINYQMV-LFTEELTEKIKNNLQIKMDSLDKNLLRIINKYQKLLEKVQKNYHNIQN-LYE 802 Query: 1289 MEQVTSLQNK--LQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXX 1346 + Q T +Q + QD++E L N + IN ++ED++ Sbjct: 803 LSQQTLIQQESAYQDQKEKLSNQINTLQEEINSKNSHIHQLEDQQKKLLLDLSNIEQQNQ 862 Query: 1347 XXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELT 1406 + + ++ + I+ + + + +V D ++++ Sbjct: 863 DKQIIINQQQLKLDEIHKTKIVELEKIVTNQQSELEQILTKSNQLEQQVQDQKSQIHSKQ 922 Query: 1407 HQL-ELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLK 1465 +++ ELK + K + + + Q +F+ + Q++E +LT ++ ++ RLK Sbjct: 923 NRINELKQELNHLKNDQTGVQIDQL--KFQQQQNQILELISNNTNLT-QQNLDIQ-RRLK 978 Query: 1466 MHENAN-------HYETMQKESEIERVKLIEELN-VKITESVSLNKQVAELNKALEEEVA 1517 E++N + T Q S+ E + +++ N ++ +S++L +Q+ L K ++ Sbjct: 979 QVEDSNQALQDKINQLTKQGASQKEIINQLQQQNQSEVKQSLALMQQMDPLQKQIDFLTR 1038 Query: 1518 KTNEMQ 1523 + ++Q Sbjct: 1039 ENRKLQ 1044 Score = 35.9 bits (79), Expect = 9.2 Identities = 68/356 (19%), Positives = 162/356 (45%), Gaps = 38/356 (10%) Query: 642 DKLADISQLQSDQVCSEIKSVHLEEQIDA-LSASKKELALVI--ENLKLDKEQLYGTIKD 698 DKL I +L + K+++L+ + SK+ +++ +++KL + K Sbjct: 3236 DKLDKIKKLNPNSSVDG-KTMYLKPSFKTKMKTSKRYFSVIFSPQSMKLKTSSMLTQKKT 3294 Query: 699 LENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLA----KINHEEQSKIQ--TQFG 752 L + ++ + + +++YI+ + + K +KI +L + +I + + KI+ T G Sbjct: 3295 LPSPQKPLKDIVKHYIKSKIPKSRTPSKSPPQKIKKLSSPQQRQIRSQSKKKIKYKTTIG 3354 Query: 753 IDAKIQERDLY--IEN--IESELSKYKSRICRLEESIAVMED-RRYSLERKADQLGSYLQ 807 K+ +++ I+N + ++SK S RL + +V ED R + + D+L + Sbjct: 3355 SPNKLTKKNKKQKIQNQYYQPQISKVSS--IRLN-TFSVSEDPHRMLMNQIIDEL-QQMN 3410 Query: 808 EKQKAYSEYTIQ--EDELVNRLAVLMDHDRV-VE-KQLLEIEHENKELQKKNQILLEENQ 863 EKQ + ++ + + V+ H+++ ++ K + HE+ L N+I + Sbjct: 3411 EKQIIDLQQFLKNIKQQKVDEALQTSLHEKIDIQLKHQQKAFHESLPLNIINEICQQRES 3470 Query: 864 NLQISLSDMQQHYNALVEKANRTDLA-----------ESESTKYQTQLRDLESNLKRITH 912 + + + ++ L+E+ + + +S+ST + +++ ++ +T+ Sbjct: 3471 TINVRVKMQMDAFSTLLEQQKISPRSFNKNGQVLEQWKSQSTDKLHKCQEILQQMQSVTN 3530 Query: 913 EHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYK 968 + Q +Q K I++LE N+ +E D L +++ ++ Q Q++K Sbjct: 3531 KIQQKTIQDMKLIQELESN-NSILEQMSADSSYLE---SQDLHLHNPIQNQQQDFK 3582 >UniRef50_A2EPG1 Cluster: Viral A-type inclusion protein, putative; n=1; Trichomonas vaginalis G3|Rep: Viral A-type inclusion protein, putative - Trichomonas vaginalis G3 Length = 1297 Score = 157 bits (382), Expect = 2e-36 Identities = 247/1164 (21%), Positives = 508/1164 (43%), Gaps = 128/1164 (10%) Query: 470 TNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKV 529 T T+ N + +V+ LKQ+L D KDV + + E + +++ Q+ +++ ++ I++ Sbjct: 16 TITQRDNALEEVKN-LKQQLEDSKKDV--ESITEDFEKTSDELEQVKEKLALKDQTEIEL 72 Query: 530 KSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYD 589 + ++ Q+++ I N S + +NK L EE+ L + E++E L+ + Sbjct: 73 QK----EITQLKEQIQNLSTEATNNKS---LNEEIQRLKSENTEIKEA---LERNKTQNK 122 Query: 590 SGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLV------QELHILQQKYDEVEDK 643 E + + E + L + S +ES K +L +EL + DE+ +K Sbjct: 123 ENSENEEVINQLTGENQKLTDENESLKSQIESLKKELSKLNQNQEELLKASGQTDELNNK 182 Query: 644 LADISQLQSDQVCSEIKSVHLEEQ-----IDALSAS----KKELALVIENLKLDKEQLYG 694 L+++ + ++ + ++KS+ E + L E+ VI NL+ +K L Sbjct: 183 LSNL-EAENKSLTEKLKSLENENSTLLGFVSTLKTQFNNMNTEVQRVIGNLEAEKTNLE- 240 Query: 695 TIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGID 754 ++ EN KE+ +L + + L D++ ++ E +E L KI E + +IQ + I Sbjct: 241 --EEFENYKENSHKQLDVHYNKITSLEDEISQLKKE--NENLIKIK-EIKEEIQVEL-IH 294 Query: 755 AKIQERDLY--IENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKA 812 K + L E+++ EL K+ + E+ I E++ +LE + D+L + ++E Sbjct: 295 MKQENEKLKKESESLQDELDTAKADLEDKEDEIEDKENQISNLEEETDELNAKIEELNST 354 Query: 813 YSEYTIQED--ELVNRLAVLMDHDRV--VEKQLLEI-------EHENKELQKKN---QIL 858 + + + E N++ ++ R+ +EKQ+ E+ E +E+QK N + L Sbjct: 355 IEKLSSNQSFSEENNQIKDSSENKRIEELEKQIEELRASQNNQESSKEEIQKLNIDIENL 414 Query: 859 LEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLI 918 +EN+NL+ +++ + + + N+ + + K + QL++ +L++ + Sbjct: 415 KKENENLKKKNTELNDSVDGMNNQINKLNKENNSLQKEKKQLQEKIESLEQQQSSNDNQF 474 Query: 919 VQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNV 978 +E L+IE N + +K LN+ + + + QL QL +N ENL + Sbjct: 475 DSSFASLEALKIELN----QSKAEKSALNDTIDGMGQQLDQLSQQLSSLRNENENLKKEL 530 Query: 979 EELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVS 1038 EE + + Q + D E+ +N + K N LK ++ E N + N A++ Sbjct: 531 EEAKSNASGQQNNNDQSLNEEIQDLKEK-LNNLEKENEKLKSQESES---NNEDNKAELE 586 Query: 1039 YMSM-VSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVR----EQDDQIK 1093 + + ++ + + ME ++ S+++ + ++ NE L +R E +D K Sbjct: 587 SLQLNLNQTKQDRDNLKETVNLMEGQLNGFSEKVNNLQKENENLNNKLRSSQSELEDAKK 646 Query: 1094 ELKETKLTFE-MNIP----KTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQ--- 1145 +L E K+ E +NI K + TI MSD N + LK Q Sbjct: 647 QLDENKMEVETLNIENNRLKQNNNNFNDTINGMSDQLNKISNERDAVQAENQQLKEQINN 706 Query: 1146 ------EEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQL 1199 E + + Q++S + N EL E +K+ + + +LT + +IN Sbjct: 707 LKSNQDNSSENNENKKQKQDKSDEENDELLEAKSKLSDSQDIIQKLTVEVESLKIEINHY 766 Query: 1200 KSKLEQLNT-----EN--DNLLSTVAEL---RSSISSAVDQRGFEIAELWKQHLAQREAD 1249 K + + N EN + L S + +L I + + E EL K L+ + Sbjct: 767 KQEKDNANESAKAQENKIEKLCSEIDQLCAKNKDILAENESLSNENEEL-KSKLSNFKDQ 825 Query: 1250 FQKTEH-ELRVQLSAFESKYEQLLDSVQSSTQ--EETNKIVTMEQVTSLQNK--LQDKEE 1304 Q ++ EL ++SA E + + + ++ Q EE+ K+ + + ++N +QDK Sbjct: 826 TQNEKNSELEEKISALEKENSEFKNKIKQQEQQIEESEKLNSEIEALKIENNRHIQDK-- 883 Query: 1305 HLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQE 1364 N+QE + Q+E L +E D K+ D ++ +Q+ + Sbjct: 884 --ANMQESANAMSQQLEKLSTENSDLKI---LQQKVLKLEEELKQKDGNNNEETLEQINK 938 Query: 1365 QSILNINEENAQLKK-----SSXXXXXXXXXXXXRVNDAEAKVL-------ELTHQLELK 1412 ++N++N +++K + + + E K++ + HQ+E + Sbjct: 939 LE-SDLNQKNEEIEKLIQLQNDVTDFLLVIEETNKEDSIEKKLVIAKDQVNKYKHQIE-E 996 Query: 1413 DSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANH 1472 +S ++ LT+ N + + K +++L E ES++A +++ Sbjct: 997 NSGYLDTAAKHLCKLTKENKALK--ESNSAKKVKSLQNLVSESESKIADKDKLINDLKEE 1054 Query: 1473 YETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIE 1532 E ++ ++E K+T S S + +E +K ++ +A ++ LE +EI Sbjct: 1055 LEMLKSQTECP----------KMTRSKSQTVESSENDKQAKKYLALIRKLMKQLEQKEIL 1104 Query: 1533 IVTLNDEITNLQNMVRASSSKIQK 1556 + LN +I++++N + S++ + Sbjct: 1105 VENLNKQISDVKNSLETRFSQMSR 1128 Score = 156 bits (379), Expect = 4e-36 Identities = 237/1187 (19%), Positives = 511/1187 (43%), Gaps = 74/1187 (6%) Query: 169 ETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAM 228 E +L + I ++D +E + K E T ++ +++E +A+ Sbjct: 7 EALAAELDQTITQRDNALE-EVKNLKQQLEDSKKDVESITEDFEKTSDELEQVKEK-LAL 64 Query: 229 EAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXX 288 + + + E Q+ + ++ + +S+ NK L + E++++ + LE+ Sbjct: 65 KDQTEIELQKEITQLKEQIQNLSTEATNNKSLNEEIQRLKSENTEIKEALERNKTQNKEN 124 Query: 289 XXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMT-ELTKKIELLEHLNCQIRQTNKELEN 347 + + + E ++ T+ E +I ++ EL+K + E L QT+ EL N Sbjct: 125 SENEEVINQLTGEN--QKLTDENESLKSQIESLKKELSKLNQNQEELLKASGQTD-ELNN 181 Query: 348 KLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEI 407 KL+ + E+K+++ K S G S +K+ ++ +++E + + K + Sbjct: 182 KLSNLEAENKSLTEKLKSLENENSTLLG--FVSTLKTQFNNMNTEVQRVIGNLEAEKTNL 239 Query: 408 AK-LEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLI 466 + E ++ +K L D Y ++ + + LI +++ + +E LI Sbjct: 240 EEEFENYKENSHKQL-DVHY--NKITSLEDEISQLKKENENLIKIKEIKEEIQVE---LI 293 Query: 467 HVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNM 526 H+ E ++ K E L+ EL+ D+ K+ ++++ E QI+ L +E D N + Sbjct: 294 HMKQENE---KLKKESESLQDELDTAKADLEDKE--DEIEDKENQISNLEEETDELNAKI 348 Query: 527 IKVKSN-HKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHL 585 ++ S KL Q +N K S NK I L +++ L E K +Q Sbjct: 349 EELNSTIEKLSSNQSFSEENNQIKDSSENKRIEELEKQIEELRASQNNQESSKEEIQKLN 408 Query: 586 VDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDK-- 643 +D ++ + ++ KK E+ + + I+ L + L +E LQ+K + +E + Sbjct: 409 IDIENLKKENENLKKKNTELNDSVDGMNNQINKLNKENNSLQKEKKQLQEKIESLEQQQS 468 Query: 644 ---------LADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYG 694 A + L+ + S+ + L + ID + +L+ + +L+ + E L Sbjct: 469 SNDNQFDSSFASLEALKIELNQSKAEKSALNDTIDGMGQQLDQLSQQLSSLRNENENLKK 528 Query: 695 TIKDLENDKEDIMNKLQNYIQENM-DLTDKLEKMSAE--KISELLAKINHEE-QSKIQT- 749 +++ +++ N + E + DL +KL + E K+ ++ N+E+ ++++++ Sbjct: 529 ELEEAKSNASGQQNNNDQSLNEEIQDLKEKLNNLEKENEKLKSQESESNNEDNKAELESL 588 Query: 750 QFGIDAKIQERDLYIENI---ESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYL 806 Q ++ Q+RD E + E +L+ + ++ L++ + ++ S + + + L Sbjct: 589 QLNLNQTKQDRDNLKETVNLMEGQLNGFSEKVNNLQKENENLNNKLRSSQSELEDAKKQL 648 Query: 807 QEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQ 866 E + I+ + L D + QL +I +E +Q +NQ L E+ NL+ Sbjct: 649 DENKMEVETLNIENNRLKQNNNNFNDTINGMSDQLNKISNERDAVQAENQQLKEQINNLK 708 Query: 867 ISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIE 926 + + ++ +K +++D E + +++L D + ++++T E ++L K EI Sbjct: 709 SNQDNSSENNENKKQKQDKSDEENDELLEAKSKLSDSQDIIQKLTVEVESL----KIEIN 764 Query: 927 DLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEEL----- 981 + E + ESA K K EK + QL A+ ++ E+L+ EEL Sbjct: 765 HYKQEKDNANESA----KAQENKIEKLCSEIDQLCAKNKDILAENESLSNENEELKSKLS 820 Query: 982 -------NKMNLELIDK--HVQKQQTQSPD---YTEQYINEINKLNALLKQKDEEIIALN 1029 N+ N EL +K ++K+ ++ + EQ I E KLN+ ++ E Sbjct: 821 NFKDQTQNEKNSELEEKISALEKENSEFKNKIKQQEQQIEESEKLNSEIEALKIENNRHI 880 Query: 1030 QKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQL--LDSKQHNEELQILVRE 1087 Q N Q S +M E KL+ + L+ +++++ ++ ++L D + E L+ + + Sbjct: 881 QDKANMQESANAMSQQLE-KLSTENSDLKILQQKVLKLEEELKQKDGNNNEETLEQINKL 939 Query: 1088 QDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEE 1147 + D ++ +E + ++ T+ +++ E +D+ +++E Sbjct: 940 ESDLNQKNEEIEKLIQLQNDVTDFLLVIE--ETNKEDSIEKKLVIAKDQVNKYKHQIEEN 997 Query: 1148 EEFIQERSVLQEQSAKLNTELQECYT--KIIQLETLNTELTGHDVVNQEQINQLKSKLEQ 1205 ++ + + K N L+E + K+ L+ L +E + IN LK +LE Sbjct: 998 SGYLDTAAKHLCKLTKENKALKESNSAKKVKSLQNLVSESESKIADKDKLINDLKEELEM 1057 Query: 1206 LNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFE 1265 L ++ + T ++ ++ SS D++ + L ++ + Q E E+ L Q+S + Sbjct: 1058 LKSQTECPKMTRSKSQTVESSENDKQAKKYLALIRKLMKQLEQKEILVEN-LNKQISDVK 1116 Query: 1266 SKYEQLLDSVQSSTQEETNKI-VTMEQVTSLQNKLQDKEEHLRNLQE 1311 + E + E+ N + +T KL+ K L Q+ Sbjct: 1117 NSLETRFSQMSRVIDEKINLFEENFDNLTDSFKKLRSKVAELPQRQQ 1163 Score = 146 bits (353), Expect = 6e-33 Identities = 188/899 (20%), Positives = 389/899 (43%), Gaps = 68/899 (7%) Query: 691 QLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQ 750 +L TI +N E++ N Q D+ E EK S+ L ++ + K QT+ Sbjct: 12 ELDQTITQRDNALEEVKNLKQQLEDSKKDVESITEDF--EKTSDELEQVKEKLALKDQTE 69 Query: 751 FGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQ 810 + +I + I+N+ +E + KS L E I ++ ++ ++ + Q K+ Sbjct: 70 IELQKEITQLKEQIQNLSTEATNNKS----LNEEIQRLKSENTEIKEALER--NKTQNKE 123 Query: 811 KAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLE---ENQNLQI 867 + +E I ++L L D + ++ Q+ ++ E +L + + LL+ + L Sbjct: 124 NSENEEVI--NQLTGENQKLTDENESLKSQIESLKKELSKLNQNQEELLKASGQTDELNN 181 Query: 868 SLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIED 927 LS+++ +L EK E+E++ + L++ + E Q +I + E + Sbjct: 182 KLSNLEAENKSLTEKLKSL---ENENSTLLGFVSTLKTQFNNMNTEVQRVIGNLEAEKTN 238 Query: 928 LEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLE 987 LE EF E++ K L+ Y K +T LE ++ + K ENL E ++ +E Sbjct: 239 LEEEFENYKENS---HKQLDVHYNK----ITSLEDEISQLKKENENLIKIKEIKEEIQVE 291 Query: 988 LIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYE 1047 LI H++++ + +E +E++ A L+ K++EI +I+N + + Sbjct: 292 LI--HMKQENEKLKKESESLQDELDTAKADLEDKEDEIEDKENQISNLEEE----TDELN 345 Query: 1048 SKLAQFTTKLENME--EEMQRVSKQLLDSKQHN--EELQILVRE----QDDQIKELKET- 1098 +K+ + + +E + + + Q+ DS ++ EEL+ + E Q++Q +E Sbjct: 346 AKIEELNSTIEKLSSNQSFSEENNQIKDSSENKRIEELEKQIEELRASQNNQESSKEEIQ 405 Query: 1099 KLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQER-SVL 1157 KL ++ K E + ++D + ++ L Q+E++ +QE+ L Sbjct: 406 KLNIDIENLKKENENLKKKNTELNDSVDGMNNQINKLNKENNSL--QKEKKQLQEKIESL 463 Query: 1158 QEQSAKLNTELQECYTKIIQLET-LNTELTGHDVVNQ------EQINQLKSKLEQLNTEN 1210 ++Q + + + + + L+ LN +N +Q++QL +L L EN Sbjct: 464 EQQQSSNDNQFDSSFASLEALKIELNQSKAEKSALNDTIDGMGQQLDQLSQQLSSLRNEN 523 Query: 1211 DNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQ 1270 +NL + E +S+ S + + E Q L ++ + +K +L+ Q S ++ + Sbjct: 524 ENLKKELEEAKSNASGQQNNNDQSLNEEI-QDLKEKLNNLEKENEKLKSQESESNNEDNK 582 Query: 1271 L-LDSVQSS-TQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIE 1328 L+S+Q + Q + ++ E V ++ +L E + NLQ++ ++ N++ +SE+E Sbjct: 583 AELESLQLNLNQTKQDRDNLKETVNLMEGQLNGFSEKVNNLQKENENLNNKLRSSQSELE 642 Query: 1329 DEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXX 1388 D K L EN KQ IN + QL K S Sbjct: 643 DAKKQLDENKMEVET--------LNIENNRLKQNNNNFNDTINGMSDQLNKISNERDAVQ 694 Query: 1389 XXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRI 1448 N + + + SE + + + NDE + +L + + I Sbjct: 695 AE-----NQQLKEQINNLKSNQDNSSENNENKKQKQDKSDEENDELLEAKSKLSDSQDII 749 Query: 1449 EDLTYEKES-ELAILRLKMHENANHYETMQKESEIERV-KLIEELNVKITESVSLNKQVA 1506 + LT E ES ++ I K ++ + +E++IE++ I++L K + ++ N+ ++ Sbjct: 750 QKLTVEVESLKIEINHYKQEKDNANESAKAQENKIEKLCSEIDQLCAKNKDILAENESLS 809 Query: 1507 ELNKALEEEVAKTNEMQTALENQEIE--IVTLNDEITNLQNMVRASSSKIQKHVSFASD 1563 N+ L+ +++ + +N E+E I L E + +N ++ +I++ S+ Sbjct: 810 NENEELKSKLSNFKDQTQNEKNSELEEKISALEKENSEFKNKIKQQEQQIEESEKLNSE 868 Score = 130 bits (315), Expect = 2e-28 Identities = 217/1051 (20%), Positives = 469/1051 (44%), Gaps = 112/1051 (10%) Query: 610 ETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQS--DQVCSEIKS--VHLE 665 + L+ + L+ Q D +++ + + +++ D+L + + + DQ E++ L+ Sbjct: 21 DNALEEVKNLKQQLEDSKKDVESITEDFEKTSDELEQVKEKLALKDQTEIELQKEITQLK 80 Query: 666 EQIDALSA---SKKELALVIENLKLDKEQLYGTIK-----DLEN-DKEDIMNKLQNYIQE 716 EQI LS + K L I+ LK + ++ ++ + EN + E+++N+L E Sbjct: 81 EQIQNLSTEATNNKSLNEEIQRLKSENTEIKEALERNKTQNKENSENEEVINQLTG---E 137 Query: 717 NMDLTDKLEKMSA--EKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKY 774 N LTD+ E + + E + + L+K+N ++ ++ D E + + N+E+E Sbjct: 138 NQKLTDENESLKSQIESLKKELSKLNQNQEELLKASGQTD----ELNNKLSNLEAENKSL 193 Query: 775 KSRICRLEESIAVMEDRRYSLERKADQLGSYLQEK-QKAYSEYTIQEDELVNRLAVLMDH 833 ++ LE + + +L+ + + + + +Q +E T E+E N Sbjct: 194 TEKLKSLENENSTLLGFVSTLKTQFNNMNTEVQRVIGNLEAEKTNLEEEFENYKENSHKQ 253 Query: 834 DRVVEKQLLEIEHENKELQKKNQILL---EENQNLQISLSDMQQHYNALVEKA----NRT 886 V ++ +E E +L+K+N+ L+ E + +Q+ L M+Q L +++ + Sbjct: 254 LDVHYNKITSLEDEISQLKKENENLIKIKEIKEEIQVELIHMKQENEKLKKESESLQDEL 313 Query: 887 DLAESESTKYQTQLRDLE---SNLKRITHEHQTLIVQKKKEIEDLEI-----EFNTQIES 938 D A+++ + ++ D E SNL+ T E I + IE L E N QI+ Sbjct: 314 DTAKADLEDKEDEIEDKENQISNLEEETDELNAKIEELNSTIEKLSSNQSFSEENNQIKD 373 Query: 939 AIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQT 998 + +K++ E+ EK IE + + + K I+ LN+++E L K N L K+ + Sbjct: 374 SSENKRI--EELEKQIEELRASQNNQESSKEEIQKLNIDIENLKKENENLKKKNTELND- 430 Query: 999 QSPDYTEQYINEINKLNALL----KQKDEEIIALNQKI----NNAQVSYMSM------VS 1044 S D IN++NK N L KQ E+I +L Q+ N S+ S+ ++ Sbjct: 431 -SVDGMNNQINKLNKENNSLQKEKKQLQEKIESLEQQQSSNDNQFDSSFASLEALKIELN 489 Query: 1045 DYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQ---------------D 1089 +++ + ++ M +++ ++S+QL + NE L+ + E + Sbjct: 490 QSKAEKSALNDTIDGMGQQLDQLSQQLSSLRNENENLKKELEEAKSNASGQQNNNDQSLN 549 Query: 1090 DQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLK----VQ 1145 ++I++LKE E K + S E + ++ LK + Sbjct: 550 EEIQDLKEKLNNLEKENEKLKSQESESNNEDNKAELESLQLNLNQTKQDRDNLKETVNLM 609 Query: 1146 EEE--EFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKL 1203 E + F ++ + LQ+++ LN +L+ + +LE +L + + E +N ++L Sbjct: 610 EGQLNGFSEKVNNLQKENENLNNKLRSSQS---ELEDAKKQLD-ENKMEVETLNIENNRL 665 Query: 1204 EQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQ--HLAQREADFQKTEHELRVQL 1261 +Q N ++ ++ +++ + IS+ D E +L +Q +L + + + + + Sbjct: 666 KQNNNNFNDTINGMSDQLNKISNERDAVQAENQQLKEQINNLKSNQDNSSENNENKKQKQ 725 Query: 1262 SAFESKYEQLLD--SVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQ 1319 + + ++LL+ S S +Q+ K+ +V SL+ ++ ++ N E N+ Sbjct: 726 DKSDEENDELLEAKSKLSDSQDIIQKLTV--EVESLKIEINHYKQEKDNANESAKAQENK 783 Query: 1320 IEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYK-QMQEQSILNINEENAQLK 1378 IE L SEI D+ A +L+++ ++K Q Q + + E+ + L+ Sbjct: 784 IEKLCSEI-DQLCAKNKDILAENESLSNENEELKSKLSNFKDQTQNEKNSELEEKISALE 842 Query: 1379 KSSXXXXXXXXXXXXRVNDAEA-----KVLELTHQLELKDSEIYQKT----HEYTITLTQ 1429 K + ++ ++E + L++ + ++D Q++ + L+ Sbjct: 843 KENSEFKNKIKQQEQQIEESEKLNSEIEALKIENNRHIQDKANMQESANAMSQQLEKLST 902 Query: 1430 RNDEFENVRQQLVEYEKRIE--DLTYEKESELAILRLKMHENANHYET---MQKESEI-E 1483 N + + ++Q++++ E+ ++ D +E+ I +L+ N + E +Q ++++ + Sbjct: 903 ENSDLKILQQKVLKLEEELKQKDGNNNEETLEQINKLESDLNQKNEEIEKLIQLQNDVTD 962 Query: 1484 RVKLIEELNVK--ITESVSLNK-QVAELNKALEE-----EVAKTNEMQTALENQEIEIVT 1535 + +IEE N + I + + + K QV + +EE + A + + EN+ ++ Sbjct: 963 FLLVIEETNKEDSIEKKLVIAKDQVNKYKHQIEENSGYLDTAAKHLCKLTKENKALKESN 1022 Query: 1536 LNDEITNLQNMVRASSSKIQKHVSFASDTKQ 1566 ++ +LQN+V S SKI +D K+ Sbjct: 1023 SAKKVKSLQNLVSESESKIADKDKLINDLKE 1053 Score = 81.0 bits (191), Expect = 2e-13 Identities = 142/663 (21%), Positives = 276/663 (41%), Gaps = 61/663 (9%) Query: 954 IEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINK 1013 +E V L+ QL++ K ++E++ + E+ + ++ +K K QT+ + EI + Sbjct: 24 LEEVKNLKQQLEDSKKDVESITEDFEKTSDELEQVKEKLALKDQTEI-----ELQKEITQ 78 Query: 1014 LNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEE-EMQRVSKQLL 1072 L ++ E A N K N ++ + + E K A K +N E E + V QL Sbjct: 79 LKEQIQNLSTE--ATNNKSLNEEIQRLKS-ENTEIKEALERNKTQNKENSENEEVINQLT 135 Query: 1073 DSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXX 1132 N++L QI+ LK K ++N + E + S + +++ +N++ Sbjct: 136 GE---NQKLTDENESLKSQIESLK--KELSKLNQNQEELLKASGQTDELNNKLSNLEAEN 190 Query: 1133 XXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKI------IQLETLNTELT 1186 L+ E + S L+ Q +NTE+Q + ++ E N + Sbjct: 191 KSLTEKLKSLE-NENSTLLGFVSTLKTQFNNMNTEVQRVIGNLEAEKTNLEEEFENYKEN 249 Query: 1187 GHDV--VNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLA 1244 H V+ +I L+ ++ QL EN+NL+ + E++ I E+ + KQ Sbjct: 250 SHKQLDVHYNKITSLEDEISQLKKENENLIK-IKEIKEEIQ-------VELIHM-KQENE 300 Query: 1245 QREADFQKTEHELRVQLSAFESKYEQLLDSVQ--SSTQEETNKI-VTMEQVTSLQNKLQD 1301 + + + + + EL + E K +++ D S+ +EET+++ +E++ S KL Sbjct: 301 KLKKESESLQDELDTAKADLEDKEDEIEDKENQISNLEEETDELNAKIEELNSTIEKLSS 360 Query: 1302 KEEHLR-NLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXX--DLRTENQS 1358 + N Q K + +IE L +IE+ + + +L+ EN++ Sbjct: 361 NQSFSEENNQIKDSSENKRIEELEKQIEELRASQNNQESSKEEIQKLNIDIENLKKENEN 420 Query: 1359 YKQMQEQ---SILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSE 1415 K+ + S+ +N + +L K + ++ E + +Q + + Sbjct: 421 LKKKNTELNDSVDGMNNQINKLNKENNSLQKEKKQLQEKIESLEQQQSSNDNQFDSSFAS 480 Query: 1416 IYQKTHEYTITLTQR---NDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANH 1472 + E + ++ ND + + QQL + +++ L E E+ L + NA+ Sbjct: 481 LEALKIELNQSKAEKSALNDTIDGMGQQLDQLSQQLSSLRNENENLKKELE-EAKSNASG 539 Query: 1473 YETMQKESEIERVK-LIEELNVKITESVSLNKQVAELNKA---LEEEVAKTNEMQTALEN 1528 + +S E ++ L E+LN E+ L Q +E N E E + N QT + Sbjct: 540 QQNNNDQSLNEEIQDLKEKLNNLEKENEKLKSQESESNNEDNKAELESLQLNLNQTKQDR 599 Query: 1529 QEI-EIVTL--------NDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKE 1579 + E V L ++++ NLQ ++K++ S D K+ DE N M E Sbjct: 600 DNLKETVNLMEGQLNGFSEKVNNLQKENENLNNKLRSSQSELEDAKKQLDE---NKMEVE 656 Query: 1580 LLD 1582 L+ Sbjct: 657 TLN 659 Score = 59.3 bits (137), Expect = 9e-07 Identities = 77/396 (19%), Positives = 166/396 (41%), Gaps = 19/396 (4%) Query: 1191 VNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFE-IAELWKQHLAQREAD 1249 ++ + L ++L+Q T+ DN L V L+ + + ++ E I E +++ + E Sbjct: 1 MSDSEFEALAAELDQTITQRDNALEEVKNLKQQLEDS--KKDVESITEDFEKTSDELEQV 58 Query: 1250 FQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHL-RN 1308 +K + + ++ + + QL + +Q+ + E TN E++ L+++ + +E L RN Sbjct: 59 KEKLALKDQTEIE-LQKEITQLKEQIQNLSTEATNNKSLNEEIQRLKSENTEIKEALERN 117 Query: 1309 LQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSIL 1368 + + N+ I + E++K+ +NQ Sbjct: 118 KTQNKENSENEEVINQLTGENQKLTDENESLKSQIESLKKELSKLNQNQEELLKASGQTD 177 Query: 1369 NINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLT 1428 +N + + L+ + + V L Q ++E+ + T Sbjct: 178 ELNNKLSNLEAENKSLTEKLKSLENENSTLLGFVSTLKTQFNNMNTEVQRVIGNLEAEKT 237 Query: 1429 QRNDEFENVRQQLVEYEKRIEDLTYEK----ESELAILRLKMHENANHYETMQKESEIER 1484 +EFEN ++ K++ D+ Y K E E++ L+ K +EN + +++E ++E Sbjct: 238 NLEEEFENYKE---NSHKQL-DVHYNKITSLEDEISQLK-KENENLIKIKEIKEEIQVEL 292 Query: 1485 VKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQ 1544 + + +E ES SL ++ LE++ + + + + N E E LN +I L Sbjct: 293 IHMKQENEKLKKESESLQDELDTAKADLEDKEDEIEDKENQISNLEEETDELNAKIEELN 352 Query: 1545 NMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKEL 1580 + + K+ + SF+ + Q +D +N +EL Sbjct: 353 STI----EKLSSNQSFSEENNQIKDSS-ENKRIEEL 383 Score = 46.0 bits (104), Expect = 0.009 Identities = 103/478 (21%), Positives = 186/478 (38%), Gaps = 55/478 (11%) Query: 151 IKEKDNALSVLQVKMKIMETTILDLQEKINEK-DQIIEAKNKATTXXXXXXXXXXXXXXX 209 +KE+ N L Q Q+K +E+ D+++EAK+K + Sbjct: 700 LKEQINNLKSNQDNSSENNENKKQKQDKSDEENDELLEAKSKLSDSQDIIQKLTVEVESL 759 Query: 210 XXE--------DTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLE 261 E D + K QEN I D+ KDI +++ +S+ E K + Sbjct: 760 KIEINHYKQEKDNANESAKAQENKIEKLCSEIDQLCAKNKDILAENESLSNENEELKS-K 818 Query: 262 AARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIE-EKGSLEIAN 320 + F+ ++ K + ELE+ KQ E EE ++ E +L+I N Sbjct: 819 LSNFKDQTQNEKNS-ELEEKISALEKENSEFKNKIKQQ-EQQIEESEKLNSEIEALKIEN 876 Query: 321 MTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTA- 379 + K + E N +Q LE KL+T ++ K + K + +K G N Sbjct: 877 NRHIQDKANMQESANAMSQQ----LE-KLSTENSDLKILQQKVLKLEEELKQKDGNNNEE 931 Query: 380 -----SKMKSPWSQLSSET------LNQDTDKKINKNEIAKLEMVIQSL--NKDLVDK-E 425 +K++S +Q + E N TD + E K + + + L KD V+K + Sbjct: 932 TLEQINKLESDLNQKNEEIEKLIQLQNDVTDFLLVIEETNKEDSIEKKLVIAKDQVNKYK 991 Query: 426 YVISEK----DTXXXXXXXXXXGKDTLI---AQLQLEHQQHMEGPSLIHVGTNTEDVNEI 478 + I E DT L + +++ Q++ S + + +N++ Sbjct: 992 HQIEENSGYLDTAAKHLCKLTKENKALKESNSAKKVKSLQNLVSESESKIADKDKLINDL 1051 Query: 479 AKVQEQLK-------------QELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKN 525 + E LK Q + D K + ++ +Q+ Q ++ NK Sbjct: 1052 KEELEMLKSQTECPKMTRSKSQTVESSENDKQAKKYLALIRKLMKQLEQKEILVENLNKQ 1111 Query: 526 MIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQL 583 + VK++ + + QM + ID + + N + LT+ L KVAEL + + ++ L Sbjct: 1112 ISDVKNSLETRFSQMSRVIDEKINLFEENFD--NLTDSFKKLRSKVAELPQRQQSISL 1167 Score = 42.7 bits (96), Expect = 0.080 Identities = 69/335 (20%), Positives = 141/335 (42%), Gaps = 25/335 (7%) Query: 1265 ESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILR 1324 +S++E L + + + N +E+V +L+ +L+D ++ + ++ E + +++E ++ Sbjct: 3 DSEFEALAAELDQTITQRDN---ALEEVKNLKQQLEDSKKDVESITEDFEKTSDELEQVK 59 Query: 1325 SEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKS---S 1381 ++ K +L TE + K + E+ I + EN ++K++ + Sbjct: 60 EKLA-LKDQTEIELQKEITQLKEQIQNLSTEATNNKSLNEE-IQRLKSENTEIKEALERN 117 Query: 1382 XXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQL 1441 +N + +LT + E S+I E + L Q +E Q Sbjct: 118 KTQNKENSENEEVINQLTGENQKLTDENESLKSQIESLKKELS-KLNQNQEELLKASGQT 176 Query: 1442 VEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSL 1501 E ++ +L E E++ +LK EN N T+ + + +N ++ + Sbjct: 177 DELNNKLSNL--EAENKSLTEKLKSLENEN--STLLGFVSTLKTQ-FNNMNTEVQRVIG- 230 Query: 1502 NKQVAELNKALEEEVAKTNE-MQTALENQEIEIVTLNDEITNL----QNMVRASSSKIQK 1556 N + + N LEEE E L+ +I +L DEI+ L +N+++ K + Sbjct: 231 NLEAEKTN--LEEEFENYKENSHKQLDVHYNKITSLEDEISQLKKENENLIKIKEIKEEI 288 Query: 1557 HVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDL 1591 V KQ +E+L ++ L D + A+ DL Sbjct: 289 QVELI-HMKQ-ENEKLKKE-SESLQDELDTAKADL 320 >UniRef50_UPI00006CC2B2 Cluster: hypothetical protein TTHERM_00661480; n=1; Tetrahymena thermophila SB210|Rep: hypothetical protein TTHERM_00661480 - Tetrahymena thermophila SB210 Length = 1613 Score = 157 bits (381), Expect = 2e-36 Identities = 238/1171 (20%), Positives = 515/1171 (43%), Gaps = 115/1171 (9%) Query: 471 NTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKL--------KSAEEQITQLNDEIDAA 522 N E N+++ Q N E+ VN+ +++E L KS +QI + + ID Sbjct: 423 NIESNNQLSSDANLGLQFNNQEVSQVNISEILESLNSQIQFIIKSLPDQIAKETEFIDFE 482 Query: 523 NKNMIKVKSNHKLKLKQMQKTI-DNFSKVSDSNKEIVR-----LTEELHHLSQKVAELEE 576 +++ L +++ K + + K + N +I+R E++ L+ +L + Sbjct: 483 EIES-RIQEQASLNAEKIFKQLKEEIFKQNKLNTKIIRRMQNSYEEQIRQLTHDYMDLMD 541 Query: 577 EKGNLQLHLVDYDS-GRMIESDVY----KKMIEMENLAETRLKAISLLESQKFDLVQELH 631 + + HL++ ++ I+S V K+ +++ L +K ++ Q ++ + Sbjct: 542 QSIAQERHLIEDETLNSTIDSSVIEFCSKQSEKIKQLQTELMKKQCMMGKQDNKNMEVIK 601 Query: 632 ILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQ 691 + K +++E+KL + ++ + ++ ++ +Q+ LS +E A + +K Q Sbjct: 602 NMVDKINQLENKLLKYTDMELEN--ENLQKIN--QQLQKLSKQSQEQAAKVFGIKHQNMQ 657 Query: 692 LYGTIKDLENDKEDIMNKLQNYIQENMDLTDK---LEKMSAEKISELLAKINHEEQSKIQ 748 TI + E I ++ Q + ++T K + ++ A+ + L I++E++ +I Sbjct: 658 SISTIN--QQLAEQIHSRQQLIDTLHQEITQKNRAIHELQAKNTN--LQNISYEKEERIT 713 Query: 749 TQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMED----RRYSLERKADQLGS 804 I ++E++L I ++ + S I RL++++ ++D ++ + + L + Sbjct: 714 ELQNI---LEEKELEINDLNKKESLLNEDIMRLKDTLVAIQDELIAKKQEISHHINDL-T 769 Query: 805 YLQEKQKAYSEYTIQ-EDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQ 863 LQEK + Y + +ELVN ++ VE+++ ++ E KE+ + L E+ Sbjct: 770 QLQEKNENYEQIEQNMNEELVNLQLEYNNYREEVEEKIEKLTLEIKEINLQKDELQEQLD 829 Query: 864 NLQISLSDMQQHYNALVEKA------NRTDLAESESTKY-----QTQLRDLESNLKRITH 912 +Q + + + L+++ N+T + E E+ + QT + + + Sbjct: 830 QIQTQKQSLSEERDVLIQEKEDLIQNNQTLIQEKENLQVEIESLQTSMEQQKDAFDKEID 889 Query: 913 EHQTLIVQ--KKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNN 970 + +++Q +K D + + Q ++LN+K + LE +++ + Sbjct: 890 AFEEIVLQIIEKGSSGDQDHHASLQQPKLTSLIEILNKKMVEVQSQKEHLEQEMKYLNQD 949 Query: 971 IENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQ 1030 IEN M VE+L + D +++ + +Y + + E ++ LL++K +++ L + Sbjct: 950 IENEKMTVEQL----YQECDNLAEEKNIMAQNY-DNALAEKKQVCELLEEKTQQLRELQE 1004 Query: 1031 KINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDD 1090 K N + + + + K AQ +LEN +E+ + ++++ + + E++ +L E+++ Sbjct: 1005 KEQNKENDFQHFENQIKEKEAQIL-ELENKLQEINKTTEEV--NSELKEKIDVL-HEKEE 1060 Query: 1091 QIKELKET--KLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEE 1148 IK LKE+ + N +E I I M +D + L Q +E Sbjct: 1061 TIKILKESLDNYNIKYNTKVSELQEIHDYISQMQNDIKQKEAQIEESNQLNQQLSNQYQE 1120 Query: 1149 EFIQERSVLQEQSAKLNT------ELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSK 1202 IQ +++ + N ++QE I L L+ NQE IN K K Sbjct: 1121 LQIQNENLIYQNQNNFNQVDLLSKQIQEQNQLIEDLNLEKNTLSTTLFSNQELINSYKLK 1180 Query: 1203 LEQL-------NTENDNLLSTVAELRSSISSA---VDQRGFEIA--ELWKQHLAQREA-- 1248 LE+L NT +AEL S++S Q+ E+ +L+++ ++ + Sbjct: 1181 LEELQQAFEFNNTTISEYEKQIAELNSTVSQLNLLCQQKDSELQNYKLYEEKISNHQLID 1240 Query: 1249 --DFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQV-TSLQNKLQ----D 1301 ++ + E ELR ++ + +L T E NKI+T+E + T L ++++ + Sbjct: 1241 KEEYDRKEKELREKIENLSKEIYELNRQNDEQTNEFANKIITLESLNTDLNDQMEQIRSE 1300 Query: 1302 KEEHLRNLQEKY----ADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQ 1357 K++ ++ ++EKY ++ QIE L+S+++ EK + EN Sbjct: 1301 KDKQIQLVKEKYQQLESEYRGQIEELQSQLKWEK-QINEDSDLHSNKKLEENYEFN-ENS 1358 Query: 1358 SYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSE-- 1415 + Q++ ++ + N ++++ + S RVN E ++++L + L+ + Sbjct: 1359 AEGQVRSGNLGSQNNQDSRQELDSYKE---------RVNILEVQIIKLKNDLQTSQNTNT 1409 Query: 1416 -IYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESEL-AILRLKMHENANHY 1473 I ++ T E +++ +L +K+ L E E ++ +I K H N Sbjct: 1410 VIERQIKGLHSTNENFAKEIDSLLIKLDNEQKKYIALQKETEEQIESITDEKRHLKMNFD 1469 Query: 1474 ETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALE-EEVAKTNEMQTALENQEIE 1532 E ++K +E E + + +L +I SL Q +L K L +V E Q++++ Q Sbjct: 1470 ELLEKMNESENFERLNQLQKEID---SLKIQNEQLQKQLSLPQVGSQIERQSSIQIQNQG 1526 Query: 1533 IVTLNDEITNLQNMVRASSSKIQKHVSFASD 1563 V E N+ + S S+ ++ +D Sbjct: 1527 QVVQKSE-QNVDKPAKKSGSEEIHEINLVND 1556 Score = 120 bits (288), Expect = 4e-25 Identities = 235/1149 (20%), Positives = 483/1149 (42%), Gaps = 86/1149 (7%) Query: 468 VGTNTEDVNE-IAKVQEQLKQELNDEIKDVNVKDLIEKL-KSAEEQITQLNDEIDAANKN 525 + TN +D + +K E+ + + ND + I+ + K + + +Q+N E + + Sbjct: 234 ISTNDDDDDVGFSKKTEKKESKNNDAANQSGLLSKIKNIFKKEDSRASQVNLEGVSNDFR 293 Query: 526 MIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGN-LQLH 584 +K + ++ +D + N+ + + S G+ Q Sbjct: 294 YCPIKKQWIFEGQEENSVLDEPPPIIPVNQGAANAQQSDQNNSVAADNSVSNLGSGAQTP 353 Query: 585 LVDYDSGRMIESDV-YKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDK 643 YD + + V Y+ +++ A+ + K + F Q++ YD + Sbjct: 354 SQAYDPKQALTRPVNYRNARDLKAKAKEKEKQKPRPAAFNFMQQQKVEENMSNYDSTANN 413 Query: 644 LADISQ-LQSDQVCSEIKS-VHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKD-LE 700 Q +Q+ + +++ S +L Q + S+ ++ ++E+L + + ++ D + Sbjct: 414 FDSTEQNIQNIESNNQLSSDANLGLQFNNQEVSQVNISEILESLNSQIQFIIKSLPDQIA 473 Query: 701 NDKEDI-MNKLQNYIQENMDLT-DKLEKMSAEKI---SELLAKINHEEQSKIQTQFGIDA 755 + E I ++++ IQE L +K+ K E+I ++L KI Q+ + Q Sbjct: 474 KETEFIDFEEIESRIQEQASLNAEKIFKQLKEEIFKQNKLNTKIIRRMQNSYEEQIR-QL 532 Query: 756 KIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSE 815 DL ++I E + +V+E E K QL + L +KQ + Sbjct: 533 THDYMDLMDQSIAQERHLIEDETLNSTIDSSVIEFCSKQSE-KIKQLQTELMKKQCMMGK 591 Query: 816 YTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQH 875 + E++ + +D +E +LL+ + + EL+ +N L + NQ LQ LS Q Sbjct: 592 QDNKNMEVIKNM---VDKINQLENKLLK--YTDMELENEN--LQKINQQLQ-KLSKQSQE 643 Query: 876 YNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQ 935 A V ++ +S ST Q + S + I HQ I QK + I +L+ + NT Sbjct: 644 QAAKVFGIKHQNM-QSISTINQQLAEQIHSRQQLIDTLHQE-ITQKNRAIHELQAK-NTN 700 Query: 936 IESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHV-- 993 ++ N YEK E +T+L+ L+E + I +LN LN+ + L D V Sbjct: 701 LQ---------NISYEKE-ERITELQNILEEKELEINDLNKKESLLNEDIMRLKDTLVAI 750 Query: 994 QKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQF 1053 Q + +IN++ +L + ++ +N+++ N Q+ Y + + E K+ + Sbjct: 751 QDELIAKKQEISHHINDLTQLQEKNENYEQIEQNMNEELVNLQLEYNNYREEVEEKIEKL 810 Query: 1054 TTKLENM---EEEMQRVSKQLLDSKQH-NEELQILVREQDDQIKELKETKLTFEMNIPKT 1109 T +++ + ++E+Q Q+ KQ +EE +L++E++D I+ +T + + N+ + Sbjct: 811 TLEIKEINLQKDELQEQLDQIQTQKQSLSEERDVLIQEKEDLIQN-NQTLIQEKENL-QV 868 Query: 1110 EGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQ 1169 E + +++E D + L++ E+ + Q KL + ++ Sbjct: 869 EIESLQTSMEQQKDAFDK-----EIDAFEEIVLQIIEKGSSGDQDHHASLQQPKLTSLIE 923 Query: 1170 ECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVD 1229 K++++++ L + I K +EQL E DNL + + +A+ Sbjct: 924 ILNKKMVEVQSQKEHLEQEMKYLNQDIENEKMTVEQLYQECDNLAEEKNIMAQNYDNALA 983 Query: 1230 QRG--FEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIV 1287 ++ E+ E Q L + + Q E++ + + + K Q+L+ +++ QE NK Sbjct: 984 EKKQVCELLEEKTQQLRELQEKEQNKENDFQHFENQIKEKEAQILE-LENKLQE-INK-- 1039 Query: 1288 TMEQVTS-LQNK---LQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXX 1343 T E+V S L+ K L +KEE ++ L+E + + SE+++ Sbjct: 1040 TTEEVNSELKEKIDVLHEKEETIKILKESLDNYNIKYNTKVSELQE----IHDYISQMQN 1095 Query: 1344 XXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVL 1403 + NQ +Q+ Q + +N L + ++ + + Sbjct: 1096 DIKQKEAQIEESNQLNQQLSNQ-YQELQIQNENLIYQNQNNFNQVDLLSKQIQEQNQLIE 1154 Query: 1404 ELTHQLELKDSEIYQKT---HEYTITLTQRNDEFENVRQQLVEYEKRIEDLT-------- 1452 +L + + ++ + Y + L + FE + EYEK+I +L Sbjct: 1155 DLNLEKNTLSTTLFSNQELINSYKLKLEELQQAFEFNNTTISEYEKQIAELNSTVSQLNL 1214 Query: 1453 --YEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNK 1510 +K+SEL +L + +NH + + KE E +R + +EL KI +L+K++ ELN+ Sbjct: 1215 LCQQKDSELQNYKLYEEKISNH-QLIDKE-EYDRKE--KELREKIE---NLSKEIYELNR 1267 Query: 1511 ALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDE 1570 +E+ TNE + E LND++ +++ +++ +G+ E Sbjct: 1268 QNDEQ---TNEFANKIITLESLNTDLNDQMEQIRSEKDKQIQLVKEKYQQLESEYRGQIE 1324 Query: 1571 QLDNTMNKE 1579 +L + + E Sbjct: 1325 ELQSQLKWE 1333 Score = 103 bits (248), Expect = 3e-20 Identities = 210/1167 (17%), Positives = 488/1167 (41%), Gaps = 98/1167 (8%) Query: 388 QLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDT 447 Q +++ ++Q +I ++ ++++ +I+SL + + I ++ + Sbjct: 439 QFNNQEVSQVNISEILESLNSQIQFIIKSLPDQIAKETEFIDFEEIESRIQEQASLNAEK 498 Query: 448 LIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKS 507 + QL+ E + + NT+ + + E+ ++L + D+ + + ++ Sbjct: 499 IFKQLKEEIFKQNK--------LNTKIIRRMQNSYEEQIRQLTHDYMDLMDQSIAQERHL 550 Query: 508 AEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDN----FSKVSDSNKEIVR-LTE 562 E++ LN ID++ +I+ S K+KQ+Q + K + N E+++ + + Sbjct: 551 IEDET--LNSTIDSS---VIEFCSKQSEKIKQLQTELMKKQCMMGKQDNKNMEVIKNMVD 605 Query: 563 ELHHLSQKVAELEE-EKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLES 621 +++ L K+ + + E N L ++ ++ + ++ ++ + +++IS + Sbjct: 606 KINQLENKLLKYTDMELENENLQKINQQLQKLSKQS-QEQAAKVFGIKHQNMQSISTINQ 664 Query: 622 QKFDLVQELHILQQKYD----EVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKE 677 Q L +++H QQ D E+ K I +LQ+ + S EE+I L +E Sbjct: 665 Q---LAEQIHSRQQLIDTLHQEITQKNRAIHELQAKNTNLQNISYEKEERITELQNILEE 721 Query: 678 LALVIENLKLDKEQLYGTIKDLEND----KEDIMNKLQNYIQENMDLTDKLEKMSAEKIS 733 L I +L + L I L++ +++++ K Q DLT EK E Sbjct: 722 KELEINDLNKKESLLNEDIMRLKDTLVAIQDELIAKKQEISHHINDLTQLQEKN--ENYE 779 Query: 734 ELLAKINHEEQSKIQTQFG-----IDAKIQERDLYIENIESELSKYKSRICRLE-ESIAV 787 ++ +N EE +Q ++ ++ KI++ L I+ I + + + ++ +++ + ++ Sbjct: 780 QIEQNMN-EELVNLQLEYNNYREEVEEKIEKLTLEIKEINLQKDELQEQLDQIQTQKQSL 838 Query: 788 MEDRRYSLERKADQLGS---YLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEI 844 E+R ++ K D + + +QEK+ E + + + E+ +L+I Sbjct: 839 SEERDVLIQEKEDLIQNNQTLIQEKENLQVEIESLQTSMEQQKDAFDKEIDAFEEIVLQI 898 Query: 845 ---------EHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTK 895 +H Q K L+E + + ++H ++ N+ E + + Sbjct: 899 IEKGSSGDQDHHASLQQPKLTSLIEILNKKMVEVQSQKEHLEQEMKYLNQDIENEKMTVE 958 Query: 896 YQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIE 955 Q D + K I ++ + +KK++ +L +E TQ +++K+ E ++ E Sbjct: 959 QLYQECDNLAEEKNIMAQNYDNALAEKKQVCEL-LEEKTQQLRELQEKEQNKENDFQHFE 1017 Query: 956 -YVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKL 1014 + + EAQ+ E +N ++ +N EE+N E ID +K++T + ++ Sbjct: 1018 NQIKEKEAQILELENKLQEINKTTEEVNSELKEKIDVLHEKEET-----IKILKESLDNY 1072 Query: 1015 NALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDS 1074 N K E+ ++ I+ Q + E Q +L N +E+Q ++ L+ Sbjct: 1073 NIKYNTKVSELQEIHDYISQMQNDIKQKEAQIEES-NQLNQQLSNQYQELQIQNENLIYQ 1131 Query: 1075 KQHN-EELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANN--VDXX 1131 Q+N ++ +L + QI+E + +L ++N+ K +S+T+ + N+ + Sbjct: 1132 NQNNFNQVDLLSK----QIQE--QNQLIEDLNLEKN---TLSTTLFSNQELINSYKLKLE 1182 Query: 1132 XXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVV 1191 + E E+ I E L ++LN Q+ +++ + +++ H ++ Sbjct: 1183 ELQQAFEFNNTTISEYEKQIAE---LNSTVSQLNLLCQQKDSELQNYKLYEEKISNHQLI 1239 Query: 1192 NQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQ 1251 ++E+ ++ K ++L + +NL + EL ++ +I L + + + Sbjct: 1240 DKEEYDR---KEKELREKIENLSKEIYELNRQNDEQTNEFANKIITLESLNTDLND-QME 1295 Query: 1252 KTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTS-----LQNKLQDKEEHL 1306 + E Q+ + KY+QL + +E +++ +Q+ KL++ E Sbjct: 1296 QIRSEKDKQIQLVKEKYQQLESEYRGQIEELQSQLKWEKQINEDSDLHSNKKLEENYEFN 1355 Query: 1307 RNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQS 1366 N E N + E ++ DL+T +Q+ + E+ Sbjct: 1356 ENSAEGQVRSGNLGSQNNQDSRQELDSYKERVNILEVQIIKLKNDLQT-SQNTNTVIERQ 1414 Query: 1367 ILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTIT 1426 I ++ N K ++++ + K + L + E + I + + Sbjct: 1415 IKGLHSTNENFAKE-------IDSLLIKLDNEQKKYIALQKETEEQIESITDEKRHLKMN 1467 Query: 1427 ---LTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRL-KMHENANHYETMQKESEI 1482 L ++ +E EN ++L + +K I+ L + E L L ++ ++Q +++ Sbjct: 1468 FDELLEKMNESENF-ERLNQLQKEIDSLKIQNEQLQKQLSLPQVGSQIERQSSIQIQNQG 1526 Query: 1483 ERVKLIEELNVKITESVSLNKQVAELN 1509 + V+ E+ NV S ++++ E+N Sbjct: 1527 QVVQKSEQ-NVDKPAKKSGSEEIHEIN 1552 Score = 94.7 bits (225), Expect = 2e-17 Identities = 198/974 (20%), Positives = 402/974 (41%), Gaps = 97/974 (9%) Query: 90 ISESLANTLKQKEILMEKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSN 149 I++ L KQ + K+ K + +S +TI + QL D H Sbjct: 630 INQQLQKLSKQSQEQAAKVFGIKHQNMQSISTINQQLAEQIHSRQ-----QLIDTLH--Q 682 Query: 150 TIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAK-------NKATTXXXXXXXX 202 I +K+ A+ LQ K ++ + +E+I E I+E K NK + Sbjct: 683 EITQKNRAIHELQAKNTNLQNISYEKEERITELQNILEEKELEINDLNKKESLLNEDIMR 742 Query: 203 XXXXXXXXXED--TKQQ--------MTKMQ---ENFIAMEAEWKDEKQRLLKDIESKDVR 249 ++ K+Q +T++Q EN+ +E +E L +E + R Sbjct: 743 LKDTLVAIQDELIAKKQEISHHINDLTQLQEKNENYEQIEQNMNEELVNL--QLEYNNYR 800 Query: 250 ISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTE 309 E+ KL + EI+L+ +L ++L+Q L ++ + +T Sbjct: 801 EEVEEKIEKLTLEIK-EINLQKDELQEQLDQIQTQKQSLSEERDVLIQEKEDLIQNNQTL 859 Query: 310 IEEKGSLEI---ANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKG 366 I+EK +L++ + T + ++ + + + ++ K + G + S K Sbjct: 860 IQEKENLQVEIESLQTSMEQQKDAFDKEIDAFEEIVLQIIEK-GSSGDQDHHASLQQPKL 918 Query: 367 SPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEY 426 + LI + + + + + + LNQD + NE +E + Q + +K Sbjct: 919 TSLIEILNKKMVEVQSQKEHLEQEMKYLNQDIE-----NEKMTVEQLYQECDNLAEEKNI 973 Query: 427 VISEKDTXXXXXXXXXXGKDTLIAQLQ--LEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQ 484 + D + QL+ E +Q+ E E +I +++ + Sbjct: 974 MAQNYDNALAEKKQVCELLEEKTQQLRELQEKEQNKENDFQHFENQIKEKEAQILELENK 1033 Query: 485 LKQELNDEIKDVN--VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQK 542 L QE+N ++VN +K+ I+ L EE I L + +D N +K N K+ ++Q+ Sbjct: 1034 L-QEINKTTEEVNSELKEKIDVLHEKEETIKILKESLDNYN-----IKYN--TKVSELQE 1085 Query: 543 TIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKM 602 D S++ + K+ EE + L+Q+++ +E +L+ + + D+ K Sbjct: 1086 IHDYISQMQNDIKQKEAQIEESNQLNQQLSNQYQELQIQNENLIYQNQNNFNQVDLLSKQ 1145 Query: 603 IEMEN------------LAETRLKAISLLESQKF---DLVQELHILQQKYDEVEDKLAD- 646 I+ +N L+ T L+ S K +L Q E E ++A+ Sbjct: 1146 IQEQNQLIEDLNLEKNTLSTTLFSNQELINSYKLKLEELQQAFEFNNTTISEYEKQIAEL 1205 Query: 647 ---ISQLQ--SDQVCSEIKSVHL-EEQI--------DALSASKKELALVIENLKLDKEQL 692 +SQL Q SE+++ L EE+I + +KEL IENL +++ Sbjct: 1206 NSTVSQLNLLCQQKDSELQNYKLYEEKISNHQLIDKEEYDRKEKELREKIENL---SKEI 1262 Query: 693 YGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQF- 751 Y + + + NK+ N DL D++E++ +EK ++ ++ E+ ++++++ Sbjct: 1263 YELNRQNDEQTNEFANKIITLESLNTDLNDQMEQIRSEKDKQI--QLVKEKYQQLESEYR 1320 Query: 752 GIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQK 811 G ++Q + + + I + + ++ +LEE+ E+ R + Q+ ++ Sbjct: 1321 GQIEELQSQLKWEKQINEDSDLHSNK--KLEENYEFNENSAEGQVRSGNLGSQNNQDSRQ 1378 Query: 812 AYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSD 871 Y + + L ++ L + + + IE + K L N+ +E +L I L + Sbjct: 1379 ELDSYKERVNILEVQIIKLKNDLQTSQNTNTVIERQIKGLHSTNENFAKEIDSLLIKLDN 1438 Query: 872 MQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIE 931 Q+ Y AL +K + K ++ E K E+ + Q +KEI+ L+I+ Sbjct: 1439 EQKKYIAL-QKETEEQIESITDEKRHLKMNFDELLEKMNESENFERLNQLQKEIDSLKIQ 1497 Query: 932 FNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQ-LQEYKNNIEN--LNMNVEELNKMNLEL 988 N Q++ + +V + E+ Q + Q +Q+ + N++ EE++++N L Sbjct: 1498 -NEQLQKQLSLPQV-GSQIERQSSIQIQNQGQVVQKSEQNVDKPAKKSGSEEIHEIN--L 1553 Query: 989 IDKHVQKQQTQSPD 1002 ++ ++ +Q PD Sbjct: 1554 VNDILRSPISQKPD 1567 Score = 91.9 bits (218), Expect = 1e-16 Identities = 218/1060 (20%), Positives = 429/1060 (40%), Gaps = 99/1060 (9%) Query: 590 SGRMIESDVYKKMIE--MENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADI 647 SG++ + YK++ + + E LK I+ + + LV++ I +Q Y ++E+ Sbjct: 51 SGQINYLNEYKQIFKNYRNTIQEGTLKNINAISDKVCKLVEDT-IQKQVYSKIENNWRVK 109 Query: 648 SQLQSDQVCSEIKSV--HLEEQIDALSASKKELAL--VIENLKLDKEQLYGTIKDLENDK 703 Q Q ++ EI S + QID L+ +I L QL + L N Sbjct: 110 IQQQHEKCFQEIVSSLQNTFSQIDELAKQNNHYTSLNIISIRSLYDNQLSQSKLQLRNIN 169 Query: 704 EDIMNKLQNYIQEN----MDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQE 759 ED + +LQN I ++ + L K E++ A SE AK +E Q K K QE Sbjct: 170 EDNLIRLQNQIDDHFKKYVSLYQKAEQIQALADSES-AKYKNEAQQK--------NKQQE 220 Query: 760 RDLYIENIESELSKYKSRICRLEESIAV----MEDRRYSLERKADQLGSYLQEKQKAYSE 815 + E++ S + I ++ V +++ S A L + + + + Sbjct: 221 KQG-----ENQTSSTQGAISTNDDDDDVGFSKKTEKKESKNNDAANQSGLLSKIKNIFKK 275 Query: 816 YTIQEDELVNRLAVLMDHDRV-VEKQ-LLEIEHENKELQKKNQILLEENQNLQISLSDMQ 873 + + VN V D ++KQ + E + EN L + I+ SD Sbjct: 276 EDSRASQ-VNLEGVSNDFRYCPIKKQWIFEGQEENSVLDEPPPIIPVNQGAANAQQSDQN 334 Query: 874 QHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKE--------- 924 A +N A++ S Y + R + + +K+K+ Sbjct: 335 NSVAADNSVSNLGSGAQTPSQAYDPKQALTRPVNYRNARDLKAKAKEKEKQKPRPAAFNF 394 Query: 925 IEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQL--EAQLQEYKNNIENLNMNVEE-L 981 ++ ++E N + + E+ +NIE QL +A L NN E +N+ E L Sbjct: 395 MQQQKVEENMSNYDSTANNFDSTEQNIQNIESNNQLSSDANLGLQFNNQEVSQVNISEIL 454 Query: 982 NKMN--LELIDKHVQKQ---QTQSPDYTE--QYINEINKLNA--LLKQKDEEIIALNQKI 1032 +N ++ I K + Q +T+ D+ E I E LNA + KQ EEI N K+ Sbjct: 455 ESLNSQIQFIIKSLPDQIAKETEFIDFEEIESRIQEQASLNAEKIFKQLKEEIFKQN-KL 513 Query: 1033 NNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVRE----Q 1088 N + M + YE ++ Q T ++ ++ + L++ + N + V E Q Sbjct: 514 NTKIIRRMQ--NSYEEQIRQLTHDYMDLMDQSIAQERHLIEDETLNSTIDSSVIEFCSKQ 571 Query: 1089 DDQIKELKETKLTFEMNIPKTEGM---IISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQ 1145 ++IK+L+ + + + K + +I + ++ ++ N + K+ Sbjct: 572 SEKIKQLQTELMKKQCMMGKQDNKNMEVIKNMVDKINQLENKLLKYTDMELENENLQKIN 631 Query: 1146 EEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQ 1205 ++ + + ++S QEQ+AK+ + + + T+N +L Q+ I+ L ++ Q Sbjct: 632 QQLQKLSKQS--QEQAAKV---FGIKHQNMQSISTINQQLAEQIHSRQQLIDTLHQEITQ 686 Query: 1206 LNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFE 1265 N L + L++ IS ++R E+ + ++ + D K E L + + Sbjct: 687 KNRAIHELQAKNTNLQN-ISYEKEERITELQNILEEKELEIN-DLNKKESLLNEDIMRLK 744 Query: 1266 SKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRS 1325 + D + + QE ++ I +T LQ K ++ E+ +N+ E+ ++ + R Sbjct: 745 DTLVAIQDELIAKKQEISHHI---NDLTQLQEKNENYEQIEQNMNEELVNLQLEYNNYRE 801 Query: 1326 EIED--EKVAFXXXXXXXXXXXXXXXXD-LRTENQSYKQ------MQEQSILNINEENAQ 1376 E+E+ EK+ D ++T+ QS + +++ ++ N+ Q Sbjct: 802 EVEEKIEKLTLEIKEINLQKDELQEQLDQIQTQKQSLSEERDVLIQEKEDLIQNNQTLIQ 861 Query: 1377 LKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSE---IYQKTHEYTITLTQRNDE 1433 K++ + DA K ++ ++ L+ E + H ++ + Sbjct: 862 EKENLQVEIESLQTSMEQQKDAFDKEIDAFEEIVLQIIEKGSSGDQDHHASLQQPKLTSL 921 Query: 1434 FENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNV 1493 E + +++VE + + E L E E+ L + E + +E + L EE N+ Sbjct: 922 IEILNKKMVEVQSQKEHL----EQEMKYLNQDIENEKMTVEQLYQECD----NLAEEKNI 973 Query: 1494 ---KITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRAS 1550 +++ KQV EL LEE+ + E+Q +N+E + ++I + + Sbjct: 974 MAQNYDNALAEKKQVCEL---LEEKTQQLRELQEKEQNKENDFQHFENQIKEKEAQILEL 1030 Query: 1551 SSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELD 1590 +K+Q+ + E++D KE + + LD Sbjct: 1031 ENKLQEINKTTEEVNSELKEKIDVLHEKEETIKILKESLD 1070 >UniRef50_A2F8N3 Cluster: Viral A-type inclusion protein, putative; n=1; Trichomonas vaginalis G3|Rep: Viral A-type inclusion protein, putative - Trichomonas vaginalis G3 Length = 1513 Score = 157 bits (381), Expect = 2e-36 Identities = 234/1095 (21%), Positives = 484/1095 (44%), Gaps = 63/1095 (5%) Query: 472 TEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQI-TQLNDEIDAANKNMIKVK 530 TE+ I+ +Q++ +L + KD E + E + +++I A + K+K Sbjct: 324 TEETMLISPMQDKNNSDLM-QFTPQKSKDENEIFFLSPEPLKNDSSEKIHALESEIQKLK 382 Query: 531 SNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGN---LQLHLVD 587 ++K + + S + + I +L E+ QK+ EL K N LQ V Sbjct: 383 QDNKSLEEALSLVNSTKSDIKELENVIEQLQGEIAEKDQKIKELSSSKENDEILQELEVQ 442 Query: 588 YDSGRMIESDVYKKM--IEMENLAETRLK-AISLLESQKFDLVQELHILQQKYDEVEDKL 644 I + KK IEM+ L+ I L+++ L +E L + + D Sbjct: 443 IQEKENISKSLQKKAEEIEMKEKENKELEQVIDSLKTEIDSLTKENEKLNKACERASDAA 502 Query: 645 ADISQLQSDQVCSEI-KSVH-LEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLEND 702 ++S+ + D + E+ K ++ EE+I + KEL I++++ DK+ N Sbjct: 503 TNLSK-ERDMIVDEMNKDINEKEEEIQNNLSKIKELEQKIKDIETDKDLTQN------NK 555 Query: 703 KEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGID-----AKI 757 E+I+N+LQN IQ N+ KLE+ E + E A++++ + +I + + +KI Sbjct: 556 SEEIINELQNKIQNNLSKIRKLEQKIKE-LEEANAQLSNNKSEEIINELQNEIQNNLSKI 614 Query: 758 QERDLYIENIES-ELSKYKS--RICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYS 814 +E + I+ +ES +LS KS I +LE IA ++ + ++ + L ++E +K + Sbjct: 615 RELEQKIKELESTQLSNNKSDETINQLEVEIAKNKETIEKINKENNYLHKKVEETEKQIN 674 Query: 815 EYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKE-LQKKNQILLEENQNLQISLSDMQ 873 +++L N + L +E ++ E +E+K+ ++K + + E + LS+++ Sbjct: 675 LLETDKNKLQNMVNELETSKSDLEAKISENSNEDKQQIEKLEESIKEIKSESERQLSELR 734 Query: 874 QHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEH-QTLIVQKKKEIEDLEIEF 932 N + + N+ +A S S + +T +++LE L E + + ++I+ + +F Sbjct: 735 NKLNEVEFEKNQ--IASSLSVEKET-VKNLEEQLSTAQSEELENANKELNEKIKQISDDF 791 Query: 933 NTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKH 992 + + ++K L + EK + ++L ++L +++IE + EL E + Sbjct: 792 SNKSSEFEKEKSDLQKILEKFKKENSELHSKLDFSEDSIEKIKSQ-SELKLTQSEKDNSE 850 Query: 993 VQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIA-LNQKINNAQVSYMSMVSDYESKLA 1051 ++K+ +Q ++++N + L++K EEI A L+QK M+ L Sbjct: 851 LRKKLSQLQREMNDSLSKLNSEKSDLERKLEEISADLSQK--------EGMLKKAMDSLK 902 Query: 1052 QFTTKLENMEEEMQRVSKQL-LDSK--QHNEELQILVREQDDQIKELKETKLTFEMN--I 1106 + +KL+ +EEE + Q+ +DS+ + + + +I +D +IK K K E N + Sbjct: 903 KMKSKLDKLEEEKSSLENQMKVDSEKAETDRKSEIAKINEDFEIKFDKLKKQLEEANNSL 962 Query: 1107 PKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNT 1166 K E + + + +D + +E +E+++L +++ L Sbjct: 963 EKKENELEEAKKALLRNDTEQ--KAEFAKLSKMSEIAHEENARIAKEKALLTKENESLKK 1020 Query: 1167 ELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISS 1226 E ++ L +EL +I+ LK + + + T+ +N L E+ + Sbjct: 1021 ENEKQKEDYSNLREKYSELEKEVKDLASEIDTLKKEKQNIETKLENELKKSNEMSQMLQI 1080 Query: 1227 AVDQRGFEIAELWKQHLAQREA--DFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETN 1284 A Q+ + A + +Q A +E+ +K EL +SA + +L ++++++ ++ Sbjct: 1081 ADSQKE-QSANMQRQIDALKESLNSTEKQNSELISSVSALSEENSKLKNTIEAAKKKVNA 1139 Query: 1285 KIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVI-NQIEILRSEIEDEKVAFXXXXXXXXX 1343 +I S +LQ+ E+L + + A+ + I+ L++EI K+ Sbjct: 1140 EIKKNSDFQSKIEELQNSIENLNSEKISQAEKAESSIKSLQNEISSLKLKISEDDEKLSS 1199 Query: 1344 XXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVL 1403 + + K + E+ I + E +++ +K S + +A K Sbjct: 1200 FESSLSQVTAEKEEIQKSLNEE-IAKMAEISSEKEKISVQLQNIQKENEQKSQEA-IKSS 1257 Query: 1404 ELTHQLELKDSEIYQKTHEYTITLTQRND--EFENVRQQLVEYEKRIEDLTYEKES-ELA 1460 ELT ++E +S + ++ E ND E+ + E EK +++ KE+ E+A Sbjct: 1258 ELTKRIEELESSLRKEIMENNNLRQVHNDVSNAEDNKHLQDENEKLRKEIEESKENFEIA 1317 Query: 1461 ILRL------KMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEE 1514 + K+ +N K S ++V+ +EE N + +S+S +++V A Sbjct: 1318 KKQFIEEESAKIEQNIKRKFEASKNSLSKKVESLEEENRNLQKSISDSEKVTRNLSAKVS 1377 Query: 1515 EVAKTNEMQTALENQ 1529 E + N + L+ Q Sbjct: 1378 EFDQINRQNSELKQQ 1392 Score = 155 bits (375), Expect = 1e-35 Identities = 249/1164 (21%), Positives = 521/1164 (44%), Gaps = 132/1164 (11%) Query: 214 TKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSK 273 T Q+ E F K++ + +ES+ I L++ NK LE A ++ S Sbjct: 345 TPQKSKDENEIFFLSPEPLKNDSSEKIHALESE---IQKLKQDNKSLEEALSLVNSTKSD 401 Query: 274 LAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIEL-LE 332 + +ELE K+ S +E EI ++ ++I ++K ++ E Sbjct: 402 I-KELENVIEQLQGEIAEKDQKIKEL--SSSKENDEILQELEVQIQEKENISKSLQKKAE 458 Query: 333 HLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSE 392 + + ++ NKELE + ++ TE +++ ++K + R S + A+ + + E Sbjct: 459 EIEMKEKE-NKELEQVIDSLKTEIDSLTKENEKLNKACERAS--DAATNLSKERDMIVDE 515 Query: 393 TLNQDTDKKINK--NEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKD-TLI 449 +N+D ++K + N ++K++ + Q + DK+ + K + + I Sbjct: 516 -MNKDINEKEEEIQNNLSKIKELEQKIKDIETDKDLTQNNKSEEIINELQNKIQNNLSKI 574 Query: 450 AQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAE 509 +L+ + ++ E + + + E +NE+ Q +++ L+ +++L +K+K E Sbjct: 575 RKLEQKIKELEEANAQLSNNKSEEIINEL---QNEIQNNLS------KIRELEQKIKELE 625 Query: 510 EQITQLNDEIDAANKNMIKVK-SNHKLKLKQMQKTIDNF--SKVSDSNKEIVRLTEELHH 566 TQL++ N ++V+ + +K ++++ K +N+ KV ++ K+I L + + Sbjct: 626 S--TQLSNNKSDETINQLEVEIAKNKETIEKINKE-NNYLHKKVEETEKQINLLETDKNK 682 Query: 567 LSQKVAELEEEKGNLQLHLV-----DYDSGRMIESDVYKKMIEMEN-LAETRLKAISLLE 620 L V ELE K +L+ + D +E + + E E L+E R K ++ +E Sbjct: 683 LQNMVNELETSKSDLEAKISENSNEDKQQIEKLEESIKEIKSESERQLSELRNK-LNEVE 741 Query: 621 SQKFDLVQELHILQQKYDEVEDKL--ADISQLQS--DQVCSEIKSVH--LEEQIDALSAS 674 +K + L + ++ +E++L A +L++ ++ +IK + + Sbjct: 742 FEKNQIASSLSVEKETVKNLEEQLSTAQSEELENANKELNEKIKQISDDFSNKSSEFEKE 801 Query: 675 KKELALVIENLKLDKEQLYGTIKDLENDKEDIMN----KLQNYIQENMDLTDKLEKMSAE 730 K +L ++E K + +L+ + E+ E I + KL ++N +L KL ++ E Sbjct: 802 KSDLQKILEKFKKENSELHSKLDFSEDSIEKIKSQSELKLTQSEKDNSELRKKLSQLQRE 861 Query: 731 KISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVME- 789 +++ L+K+N E+ + I A + +++ ++ L K KS++ +LEE + +E Sbjct: 862 -MNDSLSKLNSEKSDLERKLEEISADLSQKEGMLKKAMDSLKKMKSKLDKLEEEKSSLEN 920 Query: 790 -----------DRRYSL-------ERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLM 831 DR+ + E K D+L L+E + + +E+EL L+ Sbjct: 921 QMKVDSEKAETDRKSEIAKINEDFEIKFDKLKKQLEEANNSLEK---KENELEEAKKALL 977 Query: 832 DHDRVVEKQ------LLEIEHE-NKELQKKNQILLEENQNLQISLSDMQQHYNALVEKAN 884 +D + + + EI HE N + K+ +L +EN++L+ ++ Y+ L EK + Sbjct: 978 RNDTEQKAEFAKLSKMSEIAHEENARIAKEKALLTKENESLKKENEKQKEDYSNLREKYS 1037 Query: 885 RT-----DLA-ESESTKYQTQLRD--LESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQI 936 DLA E ++ K + Q + LE+ LK+ Q L + ++ + ++ QI Sbjct: 1038 ELEKEVKDLASEIDTLKKEKQNIETKLENELKKSNEMSQMLQIADSQKEQSANMQ--RQI 1095 Query: 937 ESAIRDKKVLNEKYEKNIEYVTQLEAQLQE---YKNNIENLNMNVEELNKMNLELIDKHV 993 ++ K+ LN ++N E ++ + A +E KN IE V K N + K + Sbjct: 1096 DAL---KESLNSTEKQNSELISSVSALSEENSKLKNTIEAAKKKVNAEIKKNSDFQSK-I 1151 Query: 994 QKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQF 1053 ++ Q + + I++ K + +K EI +L KI+ +S +ES L+Q Sbjct: 1152 EELQNSIENLNSEKISQAEKAESSIKSLQNEISSLKLKISEDD----EKLSSFESSLSQV 1207 Query: 1054 TTKLENME----EEMQRVSKQLLDSKQHNEELQILVREQDDQIKE-LKETKLTFEMNIPK 1108 T + E ++ EE+ ++++ + ++ + +LQ + +E + + +E +K ++LT I + Sbjct: 1208 TAEKEEIQKSLNEEIAKMAEISSEKEKISVQLQNIQKENEQKSQEAIKSSELT--KRIEE 1265 Query: 1109 TEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTEL 1168 E + +E NN+ +Q+E E +++ + + +K N E+ Sbjct: 1266 LESSLRKEIMEN-----NNLRQVHNDVSNAEDNKHLQDENEKLRK----EIEESKENFEI 1316 Query: 1169 QECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAV 1228 + + I+ E+ E + N L K+E L EN NL ++++ ++ + Sbjct: 1317 AK--KQFIEEESAKIEQNIKRKFEASK-NSLSKKVESLEEENRNLQKSISD-SEKVTRNL 1372 Query: 1229 DQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVT 1288 + E ++ +Q+ EL+ QLS F ++ L+ + + TQEE + + Sbjct: 1373 SAKVSEFDQINRQN------------SELKQQLSHFTKRHNDLI-AEREITQEEC--LRS 1417 Query: 1289 MEQVTSLQNKLQDKEEHLRNLQEK 1312 Q L K+ + E L LQ + Sbjct: 1418 QHQAEILTKKVSELEAKLEKLQSE 1441 Score = 151 bits (365), Expect = 2e-34 Identities = 239/1097 (21%), Positives = 476/1097 (43%), Gaps = 94/1097 (8%) Query: 449 IAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSA 508 I +L+ +++ E SL++ + D+ E+ V EQL+ E+ + KD +K+L K Sbjct: 378 IQKLKQDNKSLEEALSLVN--STKSDIKELENVIEQLQGEIAE--KDQKIKELSSS-KEN 432 Query: 509 EEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNK-EIVRLTEELHHL 567 +E + +L +I +N+ K +++ +K +V DS K EI LT+E L Sbjct: 433 DEILQELEVQIQE-KENISKSLQKKAEEIEMKEKENKELEQVIDSLKTEIDSLTKENEKL 491 Query: 568 SQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLV 627 ++ + NL + D MI ++ K + E E + L I LE + D+ Sbjct: 492 NKACERASDAATNLSK---ERD---MIVDEMNKDINEKEEEIQNNLSKIKELEQKIKDIE 545 Query: 628 QELHILQQ-KYDEVEDKLADISQLQSDQVCS-EIKSVHLEEQIDALSASKKE-----LAL 680 + + Q K +E+ ++L + Q ++ E K LEE LS +K E L Sbjct: 546 TDKDLTQNNKSEEIINELQNKIQNNLSKIRKLEQKIKELEEANAQLSNNKSEEIINELQN 605 Query: 681 VIENLKLDKEQLYGTIKDLE------NDKEDIMNKLQNYIQENMDLTDKLEKMSA---EK 731 I+N +L IK+LE N ++ +N+L+ I +N + +K+ K + +K Sbjct: 606 EIQNNLSKIRELEQKIKELESTQLSNNKSDETINQLEVEIAKNKETIEKINKENNYLHKK 665 Query: 732 ISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDR 791 + E +IN E K + Q ++ + I ++ K +I +LEESI ++ Sbjct: 666 VEETEKQINLLETDKNKLQNMVNELETSKSDLEAKISENSNEDKQQIEKLEESIKEIKSE 725 Query: 792 RYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKEL 851 ER+ +L + L E + + + I V + V +++ Q E+E+ NKEL Sbjct: 726 S---ERQLSELRNKLNEVE--FEKNQIASSLSVEKETVKNLEEQLSTAQSEELENANKEL 780 Query: 852 QKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRIT 911 +K + + ++ N + ++EK + E+++ ++L E ++++I Sbjct: 781 NEKIKQISDDFSNKSSEFEKEKSDLQKILEKFKK------ENSELHSKLDFSEDSIEKIK 834 Query: 912 HEHQTLIVQKKKE-------IEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQL 964 + + + Q +K+ + L+ E N + +K L K E+ ++Q E L Sbjct: 835 SQSELKLTQSEKDNSELRKKLSQLQREMNDSLSKLNSEKSDLERKLEEISADLSQKEGML 894 Query: 965 QEYKNNIENLNMNVEELNKMNLELIDK-HVQKQQTQSPDYTE-QYINEIN--KLNALLKQ 1020 ++ ++++ + +++L + L ++ V ++ ++ +E INE K + L KQ Sbjct: 895 KKAMDSLKKMKSKLDKLEEEKSSLENQMKVDSEKAETDRKSEIAKINEDFEIKFDKLKKQ 954 Query: 1021 KDEEIIALNQKINNAQVSYMSMV-SDYESK--LAQFTTKLENMEEEMQRVSKQLLDSKQH 1077 +E +L +K N + + +++ +D E K A+ + E EE R++K+ + Sbjct: 955 LEEANNSLEKKENELEEAKKALLRNDTEQKAEFAKLSKMSEIAHEENARIAKEKALLTKE 1014 Query: 1078 NEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXX 1137 NE L+ +Q + L+E E + ++S I+ + + N++ Sbjct: 1015 NESLKKENEKQKEDYSNLREKYSELEKEVKD-----LASEIDTLKKEKQNIETKLENELK 1069 Query: 1138 XXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQIN 1197 K E + +Q +EQSA + ++ + E N+EL E+ + Sbjct: 1070 -----KSNEMSQMLQIADSQKEQSANMQRQIDALKESLNSTEKQNSELISSVSALSEENS 1124 Query: 1198 QLKSKLE----QLNTE---NDNLLSTVAELRSSISSAVDQR--GFEIAELWKQHLAQREA 1248 +LK+ +E ++N E N + S + EL++SI + ++ E AE + L + Sbjct: 1125 KLKNTIEAAKKKVNAEIKKNSDFQSKIEELQNSIENLNSEKISQAEKAESSIKSLQNEIS 1184 Query: 1249 DFQKTEHELRVQLSAFESKYEQLL---DSVQSSTQEETNKIVTM----EQVTSLQNKLQD 1301 + E +LS+FES Q+ + +Q S EE K+ + E+++ +Q Sbjct: 1185 SLKLKISEDDEKLSSFESSLSQVTAEKEEIQKSLNEEIAKMAEISSEKEKISVQLQNIQK 1244 Query: 1302 KEEHLRNLQEKYADVINQIEILRSEIEDEKVA-FXXXXXXXXXXXXXXXXDLRTENQSYK 1360 + E K +++ +IE L S + E + L+ EN+ + Sbjct: 1245 ENEQKSQEAIKSSELTKRIEELESSLRKEIMENNNLRQVHNDVSNAEDNKHLQDENEKLR 1304 Query: 1361 QMQEQSILN--------INEENAQLKKS-SXXXXXXXXXXXXRVNDAEAKVLELTHQLEL 1411 + E+S N I EE+A+++++ +V E + L Q + Sbjct: 1305 KEIEESKENFEIAKKQFIEEESAKIEQNIKRKFEASKNSLSKKVESLEEENRNL--QKSI 1362 Query: 1412 KDSEIYQKTHEYTIT-LTQRNDEFENVRQQLVEYEKRIEDLTYEKE-SELAILRLKMHEN 1469 DSE + ++ Q N + ++QQL + KR DL E+E ++ LR + Sbjct: 1363 SDSEKVTRNLSAKVSEFDQINRQNSELKQQLSHFTKRHNDLIAEREITQEECLRSQHQAE 1422 Query: 1470 ANHYETMQKESEIERVK 1486 + + E+++E+++ Sbjct: 1423 ILTKKVSELEAKLEKLQ 1439 Score = 125 bits (301), Expect = 1e-26 Identities = 208/1091 (19%), Positives = 479/1091 (43%), Gaps = 93/1091 (8%) Query: 144 VTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXX 203 + LS++ KE D L L+V+++ E LQ+K E IE K K Sbjct: 423 IKELSSS-KENDEILQELEVQIQEKENISKSLQKKAEE----IEMKEKENKELEQVIDSL 477 Query: 204 XXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQR-LLKDIESKDVRISSLEEANKLLEA 262 ++ +++ K E A +A K+R ++ D +KD+ E N L + Sbjct: 478 KTEIDSLTKE-NEKLNKACER--ASDAATNLSKERDMIVDEMNKDINEKEEEIQNNLSKI 534 Query: 263 ARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQ-SIEPSCEEKTEIEEKGSLEIANM 321 E ++ + ++L Q + S E+K + E+ + +++N Sbjct: 535 KELEQKIKDIETDKDLTQNNKSEEIINELQNKIQNNLSKIRKLEQKIKELEEANAQLSN- 593 Query: 322 TELTKKIELLEHLNCQIRQT---NKELENKLATMGTESKAVSSPSKKGSPL-ISRKSGRN 377 K E++ L +I+ +ELE K+ + + + + + + L + + Sbjct: 594 ---NKSEEIINELQNEIQNNLSKIRELEQKIKELESTQLSNNKSDETINQLEVEIAKNKE 650 Query: 378 TASKMKSPWSQLSSETLNQDTDKKIN--KNEIAKLEMVIQSLNKDLVDKEYVISEKDTXX 435 T K+ + L + ++T+K+IN + + KL+ ++ L D E ISE Sbjct: 651 TIEKINKENNYLHKKV--EETEKQINLLETDKNKLQNMVNELETSKSDLEAKISENSNED 708 Query: 436 XXXXXXXXGKDTLIAQLQLEHQQHME--GPSLIHVGTNTEDVNEIAKVQEQLKQELNDEI 493 + I +++ E ++ + L V + V+++ + L +++ Sbjct: 709 KQQIEKL---EESIKEIKSESERQLSELRNKLNEVEFEKNQIASSLSVEKETVKNLEEQL 765 Query: 494 KDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDS 553 ++L K E+I Q++D+ + K KS+ + L++ +K D Sbjct: 766 STAQSEELENANKELNEKIKQISDDFSNKSSEFEKEKSDLQKILEKFKKENSELHSKLDF 825 Query: 554 NKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRL 613 +++ + + L K+ + E++ L+ L R + + K E +L E +L Sbjct: 826 SEDSIEKIKSQSEL--KLTQSEKDNSELRKKLSQLQ--REMNDSLSKLNSEKSDL-ERKL 880 Query: 614 KAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSA 673 + IS DL Q+ +L++ D ++ + + +L+ ++ S +++ + A + Sbjct: 881 EEISA------DLSQKEGMLKKAMDSLKKMKSKLDKLEEEK--SSLENQMKVDSEKAETD 932 Query: 674 SKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKIS 733 K E+A + E+ ++ ++L +++ N E N+L+ ++ + D +K K+S Sbjct: 933 RKSEIAKINEDFEIKFDKLKKQLEEANNSLEKKENELEE-AKKALLRNDTEQKAEFAKLS 991 Query: 734 ELLAKINHEEQSKIQTQFGIDAKIQERDLYIEN--IESELSKYKSRICRLEESIAVMEDR 791 + +++I HEE ++I + + K + L EN + + S + + LE+ + + Sbjct: 992 K-MSEIAHEENARIAKEKALLTK-ENESLKKENEKQKEDYSNLREKYSELEKEVKDLASE 1049 Query: 792 RYSLERKADQLGSYLQEKQKAYSEYT--IQ-EDELVNRLAVLMDHDRVVEKQLLEIEHEN 848 +L+++ + + L+ + K +E + +Q D + A + +++ L E +N Sbjct: 1050 IDTLKKEKQNIETKLENELKKSNEMSQMLQIADSQKEQSANMQRQIDALKESLNSTEKQN 1109 Query: 849 KELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLK 908 EL L EEN L+ ++ ++ NA ++K ++ +Q+++ +L+++++ Sbjct: 1110 SELISSVSALSEENSKLKNTIEAAKKKVNAEIKK----------NSDFQSKIEELQNSIE 1159 Query: 909 RITHEHQTLIVQKKKEIEDLEIEFNT-QIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEY 967 + E + + + I+ L+ E ++ +++ + D+K+ +E ++ VT + ++Q Sbjct: 1160 NLNSEKISQAEKAESSIKSLQNEISSLKLKISEDDEKL--SSFESSLSQVTAEKEEIQ-- 1215 Query: 968 KNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIA 1027 ++LN + ++ +++ E VQ Q Q + EQ E K + L K+ +E + Sbjct: 1216 ----KSLNEEIAKMAEISSEKEKISVQLQNIQKEN--EQKSQEAIKSSELTKRIEELESS 1269 Query: 1028 LNQKI--NNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNE-ELQIL 1084 L ++I NN + VS+ E +++++E +++ K++ +SK++ E + Sbjct: 1270 LRKEIMENNNLRQVHNDVSNAEDN--------KHLQDENEKLRKEIEESKENFEIAKKQF 1321 Query: 1085 VREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXL-- 1142 + E+ +I++ + K N +S +E + ++ N+ L Sbjct: 1322 IEEESAKIEQNIKRKFEASKN-------SLSKKVESLEEENRNLQKSISDSEKVTRNLSA 1374 Query: 1143 KVQEEEEFIQERSVLQEQSAKLNTELQECYT--KIIQLETLNTELTGHDVVNQEQINQLK 1200 KV E ++ ++ S L++Q + + +I Q E L ++ + +++++L+ Sbjct: 1375 KVSEFDQINRQNSELKQQLSHFTKRHNDLIAEREITQEECLRSQHQAE--ILTKKVSELE 1432 Query: 1201 SKLEQLNTEND 1211 +KLE+L +E D Sbjct: 1433 AKLEKLQSEAD 1443 Score = 122 bits (294), Expect = 8e-26 Identities = 220/1169 (18%), Positives = 489/1169 (41%), Gaps = 93/1169 (7%) Query: 470 TNTEDV--NEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMI 527 TN ++V ++A + E L Q+ N +I + K I++L E++ + N+E++ Sbjct: 60 TNEKEVLQRQLATLNEHL-QKKNSQISEA--KTYIKRLAIENEKLKR-NNEMEELILAFD 115 Query: 528 KVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVD 587 + + ++ +++ ++K D V + + I +L +E Q + + + G+L L Sbjct: 116 EDRKKYEREIEVLRKRADGDGIVDELLQNITKLEKENEEKDQIIQQYKG--GSLFSGLKS 173 Query: 588 YDSGRMIESDVYKKMIEMENLAETR--LKAISLLESQKFDLVQELHILQQKYDEVEDKLA 645 + + K E+ NL + LK +S + + +Q+ Q++ E + + Sbjct: 174 FIQQSSDDDPTAKFKSEIANLKKELYLLKRNKSTDSPQEEELQQPPTPQEQPKEPQREEN 233 Query: 646 DISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDK-----EQLYGTIKDLE 700 S S +K E+ K L NLK + ++L+ Sbjct: 234 PKPSENSKGFFSSLKLPKAEDPEKNAHLPKMLLGGNASNLKPESTTRLTDELFPDFSTAG 293 Query: 701 NDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQER 760 E + E +++ K + SA +L ++ + QF E Sbjct: 294 KSPEQPKFGDFSTASEKENISPKFDDFSAATEETMLISPMQDKNNSDLMQFTPQKSKDEN 353 Query: 761 DLY--------------IENIESELSKYKSRICRLEESIAVMEDRRYS---LERKADQLG 803 +++ I +ESE+ K K LEE+++++ + LE +QL Sbjct: 354 EIFFLSPEPLKNDSSEKIHALESEIQKLKQDNKSLEEALSLVNSTKSDIKELENVIEQLQ 413 Query: 804 SYLQEKQKAYSEYTI--QEDELVNRLAVLMDHDRVVEKQL------LEI-EHENKELQK- 853 + EK + E + + DE++ L V + + K L +E+ E ENKEL++ Sbjct: 414 GEIAEKDQKIKELSSSKENDEILQELEVQIQEKENISKSLQKKAEEIEMKEKENKELEQV 473 Query: 854 ----KNQI--LLEENQNLQISL-------SDMQQHYNALVEKANRT-DLAESESTKYQTQ 899 K +I L +EN+ L + +++ + + +V++ N+ + E E ++ Sbjct: 474 IDSLKTEIDSLTKENEKLNKACERASDAATNLSKERDMIVDEMNKDINEKEEEIQNNLSK 533 Query: 900 LRDLESNLKRITHEHQTLIVQKKKEI-EDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVT 958 +++LE +K I + K +EI +L+ + + + ++ + E E N + Sbjct: 534 IKELEQKIKDIETDKDLTQNNKSEEIINELQNKIQNNLSKIRKLEQKIKELEEANAQLSN 593 Query: 959 -QLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNAL 1017 + E + E +N I+N + EL + EL + Q +S + Q EI K Sbjct: 594 NKSEEIINELQNEIQNNLSKIRELEQKIKEL--ESTQLSNNKSDETINQLEVEIAKNKET 651 Query: 1018 LKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQ-RVSKQLLDSKQ 1076 +++ ++E L++K+ + + +D ++KL +LE + +++ ++S+ + KQ Sbjct: 652 IEKINKENNYLHKKVEETEKQINLLETD-KNKLQNMVNELETSKSDLEAKISENSNEDKQ 710 Query: 1077 HNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXX 1136 E+L+ ++E + E + ++L ++N + E I+S++ + N++ Sbjct: 711 QIEKLEESIKEIKSE-SERQLSELRNKLNEVEFEKNQIASSLSVEKETVKNLEEQLSTAQ 769 Query: 1137 XXXXXLKVQEEEEFIQERSV-LQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQ 1195 +E E I++ S +S++ E + + + + N+EL +++ Sbjct: 770 SEELENANKELNEKIKQISDDFSNKSSEFEKEKSDLQKILEKFKKENSELHSKLDFSEDS 829 Query: 1196 INQLKS----KLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQ 1251 I ++KS KL Q +N L +++L+ ++ ++ + E ++L ++ L + AD Sbjct: 830 IEKIKSQSELKLTQSEKDNSELRKKLSQLQREMNDSLSKLNSEKSDL-ERKLEEISADLS 888 Query: 1252 KTEHELRVQLSAFESKYEQLLDSVQS--STQEETNKIVTMEQVTSLQNKL----QDKEEH 1305 + E L+ + + + K + LD ++ S+ E K+ + + T ++++ +D E Sbjct: 889 QKEGMLKKAMDSLK-KMKSKLDKLEEEKSSLENQMKVDSEKAETDRKSEIAKINEDFEIK 947 Query: 1306 LRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQ 1365 L+++ + N +E +E+E+ K A ++ ++ ++ Sbjct: 948 FDKLKKQLEEANNSLEKKENELEEAKKALLRNDTEQKAEFAKLSKMSEIAHEENARIAKE 1007 Query: 1366 SILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTI 1425 L + +EN LKK + + ++ E +V +L +++ +K + Sbjct: 1008 KAL-LTKENESLKKENEKQKEDYSNLREKYSELEKEVKDLASEIDT-----LKKEKQNIE 1061 Query: 1426 TLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERV 1485 T + + N Q+++ ++ + + ++ L+ E+ N E E I V Sbjct: 1062 TKLENELKKSNEMSQMLQIADSQKEQSANMQRQIDALK----ESLNSTEKQNSEL-ISSV 1116 Query: 1486 KLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQN 1545 + E N K+ ++ K K + E+ K ++ Q+ +E + I LN E + Sbjct: 1117 SALSEENSKLKNTIEAAK------KKVNAEIKKNSDFQSKIEELQNSIENLNSEKISQAE 1170 Query: 1546 MVRASSSKIQKHVSFASDTKQGRDEQLDN 1574 +S +Q +S DE+L + Sbjct: 1171 KAESSIKSLQNEISSLKLKISEDDEKLSS 1199 Score = 119 bits (287), Expect = 6e-25 Identities = 222/1120 (19%), Positives = 483/1120 (43%), Gaps = 103/1120 (9%) Query: 143 DVTHLSNTIKEKDNALSVL---QVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXX 199 ++ L K + ALS++ + +K +E I LQ +I EKDQ I K +++ Sbjct: 377 EIQKLKQDNKSLEEALSLVNSTKSDIKELENVIEQLQGEIAEKDQKI--KELSSSKENDE 434 Query: 200 XXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKD-IESKDVRISSLEEANK 258 E+ + + K E E E K+++ + L+ I+S I SL + N+ Sbjct: 435 ILQELEVQIQEKENISKSLQKKAE-----EIEMKEKENKELEQVIDSLKTEIDSLTKENE 489 Query: 259 LLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEK-GSLE 317 L A S + L++E + ++ I+ + + E+E+K +E Sbjct: 490 KLNKACERASDAATNLSKERDMIVDEMNKDINEK----EEEIQNNLSKIKELEQKIKDIE 545 Query: 318 I-ANMTELTKKIELLEHLNCQIRQTN---KELENKLATMGTESKAVSSPSKKGSPLISRK 373 ++T+ K E++ L +I+ ++LE K+ + + +S+ K +I+ Sbjct: 546 TDKDLTQNNKSEEIINELQNKIQNNLSKIRKLEQKIKELEEANAQLSN--NKSEEIINEL 603 Query: 374 SG--RNTASKMKSPWSQL----SSETLNQDTDKKINKNE--IAKLEMVIQSLNKDLVDKE 425 +N SK++ ++ S++ N +D+ IN+ E IAK + I+ +NK+ Sbjct: 604 QNEIQNNLSKIRELEQKIKELESTQLSNNKSDETINQLEVEIAKNKETIEKINKE---NN 660 Query: 426 YVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQL 485 Y+ + + K+ L + + + I +N ED +I K++E + Sbjct: 661 YLHKKVEETEKQINLLETDKNKLQNMVNELETSKSDLEAKISENSN-EDKQQIEKLEESI 719 Query: 486 KQ----------ELNDEIKDVNVK--DLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNH 533 K+ EL +++ +V + + L +E + L +++ A ++ +N Sbjct: 720 KEIKSESERQLSELRNKLNEVEFEKNQIASSLSVEKETVKNLEEQLSTAQSEELE-NANK 778 Query: 534 KL--KLKQMQKTIDNFS-----KVSDSNKEIVRLTEELHHLSQKVA----ELEEEKGNLQ 582 +L K+KQ+ N S + SD K + + +E L K+ +E+ K + Sbjct: 779 ELNEKIKQISDDFSNKSSEFEKEKSDLQKILEKFKKENSELHSKLDFSEDSIEKIKSQSE 838 Query: 583 LHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHI----LQQKYD 638 L L + S++ KK+ +++ L S L S+K DL ++L L QK Sbjct: 839 LKLTQSEKDN---SELRKKLSQLQREMNDSL---SKLNSEKSDLERKLEEISADLSQKEG 892 Query: 639 EVEDKLADISQLQS--DQVCSEIKSVHLEEQIDALSAS---KKELALVIENLKLDKEQLY 693 ++ + + +++S D++ E S+ + ++D+ A K E+A + E+ ++ ++L Sbjct: 893 MLKKAMDSLKKMKSKLDKLEEEKSSLENQMKVDSEKAETDRKSEIAKINEDFEIKFDKLK 952 Query: 694 GTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGI 753 +++ N E N+L+ ++ + D +K K+S++ ++I HEE ++I + + Sbjct: 953 KQLEEANNSLEKKENELEE-AKKALLRNDTEQKAEFAKLSKM-SEIAHEENARIAKEKAL 1010 Query: 754 DAKIQERDLYIENIES--ELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQK 811 K E L EN + + S + + LE+ + + +L+++ + + L+ + K Sbjct: 1011 LTKENE-SLKKENEKQKEDYSNLREKYSELEKEVKDLASEIDTLKKEKQNIETKLENELK 1069 Query: 812 AYSEYT--IQ-EDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQIS 868 +E + +Q D + A + +++ L E +N EL L EEN L+ + Sbjct: 1070 KSNEMSQMLQIADSQKEQSANMQRQIDALKESLNSTEKQNSELISSVSALSEENSKLKNT 1129 Query: 869 LSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDL 928 + ++ NA ++K ++ +Q+++ +L+++++ + E + + + I+ L Sbjct: 1130 IEAAKKKVNAEIKK----------NSDFQSKIEELQNSIENLNSEKISQAEKAESSIKSL 1179 Query: 929 EIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNN-IENLNMNVEELNKMNLE 987 + E ++ D + L+ +E ++ VT + ++Q+ N I + E K++++ Sbjct: 1180 QNEISSLKLKISEDDEKLSS-FESSLSQVTAEKEEIQKSLNEEIAKMAEISSEKEKISVQ 1238 Query: 988 LIDKHVQK---QQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVS 1044 L +++QK Q++Q + + I +L + L+++ E L Q N+ VS Sbjct: 1239 L--QNIQKENEQKSQEAIKSSELTKRIEELESSLRKEIMENNNLRQVHND--VSNAEDNK 1294 Query: 1045 DYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEM 1104 + + + ++E +E + KQ ++ + E I + + + K+ + E Sbjct: 1295 HLQDENEKLRKEIEESKENFEIAKKQFIEEESAKIEQNIKRKFEASKNSLSKKVESLEEE 1354 Query: 1105 NIPKTEGMIISSTI-EPMSDDANNVDXXXXXXXXXXXXLK--VQEEEEFIQERSVLQEQS 1161 N + + S + +S + D L + + I ER + QE+ Sbjct: 1355 NRNLQKSISDSEKVTRNLSAKVSEFDQINRQNSELKQQLSHFTKRHNDLIAEREITQEEC 1414 Query: 1162 AKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKS 1201 + + + K+ +LE +L + N KS Sbjct: 1415 LRSQHQAEILTKKVSELEAKLEKLQSEADPSSNSRNSTKS 1454 Score = 72.1 bits (169), Expect = 1e-10 Identities = 138/668 (20%), Positives = 279/668 (41%), Gaps = 64/668 (9%) Query: 67 VSKRIKEHRKATAELLGRPFVPGISESLANTLKQKEI-LMEKIKQYKELSKRSSTTIVRX 125 + K +++ +K +EL + + +S+ Q E+ L + K EL K+ S + R Sbjct: 805 LQKILEKFKKENSELHSK--LDFSEDSIEKIKSQSELKLTQSEKDNSELRKKLSQ-LQRE 861 Query: 126 XXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQE-KINEKDQ 184 + +S + +K+ L +K M++ + L+E K + ++Q Sbjct: 862 MNDSLSKLNSEKSDLERKLEEISADLSQKEGMLKKAMDSLKKMKSKLDKLEEEKSSLENQ 921 Query: 185 IIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLK-DI 243 + KA T + K+Q+ + + E E ++ K+ LL+ D Sbjct: 922 MKVDSEKAETDRKSEIAKINEDFEIKFDKLKKQLEEANNSLEKKENELEEAKKALLRNDT 981 Query: 244 ESKD--VRISSL----EEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAK 297 E K ++S + E N + + ++ E+ L +E E+ L K Sbjct: 982 EQKAEFAKLSKMSEIAHEENARIAKEKALLTKENESLKKENEKQKEDYSNLREKYSELEK 1041 Query: 298 QSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELE-NKLATMGTES 356 + + + E T +EK ++E EL K E+ + L QI + KE N + Sbjct: 1042 EVKDLASEIDTLKKEKQNIETKLENELKKSNEMSQML--QIADSQKEQSANMQRQIDALK 1099 Query: 357 KAVSSPSKKGSPLISRKSGRNTA-SKMK----SPWSQLSSE-TLNQDTDKKI-------- 402 ++++S K+ S LIS S + SK+K + ++++E N D KI Sbjct: 1100 ESLNSTEKQNSELISSVSALSEENSKLKNTIEAAKKKVNAEIKKNSDFQSKIEELQNSIE 1159 Query: 403 --NKNEIA---KLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQ 457 N +I+ K E I+SL ++ + ISE D + +++ Sbjct: 1160 NLNSEKISQAEKAESSIKSLQNEISSLKLKISEDDEKLSSFESSL--SQVTAEKEEIQKS 1217 Query: 458 QHMEGPSLIHVGTNTEDVN-EIAKVQEQLKQELNDEIKDVNVKDLIEKLKSA-------E 509 + E + + + E ++ ++ +Q++ +Q+ + IK + IE+L+S+ Sbjct: 1218 LNEEIAKMAEISSEKEKISVQLQNIQKENEQKSQEAIKSSELTKRIEELESSLRKEIMEN 1277 Query: 510 EQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNF--SKVSDSNKEIVRLTEEL--- 564 + Q+++++ A N N KL+ K+++++ +NF +K +E ++ + + Sbjct: 1278 NNLRQVHNDVSNAEDNKHLQDENEKLR-KEIEESKENFEIAKKQFIEEESAKIEQNIKRK 1336 Query: 565 -----HHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEME--NLAETRLK-AI 616 + LS+KV LEEE NLQ + D + + ++ K+ E + N + LK + Sbjct: 1337 FEASKNSLSKKVESLEEENRNLQKSISDSEK---VTRNLSAKVSEFDQINRQNSELKQQL 1393 Query: 617 SLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKK 676 S + DL+ E I Q++ + + +++ S+ E K L+ + D S S+ Sbjct: 1394 SHFTKRHNDLIAEREITQEECLRSQHQAEILTKKVSE---LEAKLEKLQSEADPSSNSRN 1450 Query: 677 ELALVIEN 684 + N Sbjct: 1451 STKSIDPN 1458 Score = 66.9 bits (156), Expect = 4e-09 Identities = 121/696 (17%), Positives = 278/696 (39%), Gaps = 48/696 (6%) Query: 919 VQKKKEIEDLEIE-FNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMN 977 +Q++KE +D++++ F + +K+VL + E++ + +Q+ E K I+ L + Sbjct: 38 MQQEKEAKDMKLQAFENMVSEITNEKEVLQRQLATLNEHLQKKNSQISEAKTYIKRLAIE 97 Query: 978 VEELNKMNL--ELI------------DKHVQKQQTQSPDYTEQYINEINKLNALLKQKDE 1023 E+L + N ELI + V +++ ++ + I KL ++KD+ Sbjct: 98 NEKLKRNNEMEELILAFDEDRKKYEREIEVLRKRADGDGIVDELLQNITKLEKENEEKDQ 157 Query: 1024 EIIALNQ-KINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQ 1082 I + + S++ SD + A+F +++ N+++E+ + + EELQ Sbjct: 158 IIQQYKGGSLFSGLKSFIQQSSD-DDPTAKFKSEIANLKKELYLLKRNKSTDSPQEEELQ 216 Query: 1083 ILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXL 1142 Q+ + +E N ++G S + D N L Sbjct: 217 QPPTPQEQPKEPQREENPKPSEN---SKGFFSSLKLPKAEDPEKNAHLPKMLLGGNASNL 273 Query: 1143 KVQEEEEFIQE---------RSVLQEQSAKLNT--ELQECYTKIIQLETLNTE-LTGHDV 1190 K + E +S Q + +T E + K E + + Sbjct: 274 KPESTTRLTDELFPDFSTAGKSPEQPKFGDFSTASEKENISPKFDDFSAATEETMLISPM 333 Query: 1191 VNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADF 1250 ++ + ++ ++ EN+ + L++ S + EI +L + + + EA Sbjct: 334 QDKNNSDLMQFTPQKSKDENEIFFLSPEPLKNDSSEKIHALESEIQKLKQDNKSLEEA-- 391 Query: 1251 QKTEHELRVQLSAFESKYEQLLDSVQSSTQ---EETNKIVTMEQVTSLQNKLQDKEEHLR 1307 + + + E+ EQL + Q E ++ E + L+ ++Q+KE + Sbjct: 392 LSLVNSTKSDIKELENVIEQLQGEIAEKDQKIKELSSSKENDEILQELEVQIQEKENISK 451 Query: 1308 NLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSI 1367 +LQ+K A+ I E E+E + + + + ++ Sbjct: 452 SLQKK-AEEIEMKEKENKELEQVIDSLKTEIDSLTKENEKLNKACERASDAATNLSKERD 510 Query: 1368 LNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLEL-KDSEIYQKTHEYTIT 1426 + ++E N + + ++ + E K+ ++ +L ++++ + +E Sbjct: 511 MIVDEMNKDINEKE----EEIQNNLSKIKELEQKIKDIETDKDLTQNNKSEEIINELQNK 566 Query: 1427 LTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVK 1486 + + + Q++ E E+ L+ K E+ I L+ N + + E +I+ ++ Sbjct: 567 IQNNLSKIRKLEQKIKELEEANAQLSNNKSEEI-INELQNEIQNNLSKIRELEQKIKELE 625 Query: 1487 LIEELNVKITESVS-LNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQN 1545 + N K E+++ L ++A+ + +E+ + N + +E E +I L + LQN Sbjct: 626 STQLSNNKSDETINQLEVEIAKNKETIEKINKENNYLHKKVEETEKQINLLETDKNKLQN 685 Query: 1546 MV---RASSSKIQKHVSFASDTKQGRDEQLDNTMNK 1578 MV S S ++ +S S+ + + E+L+ ++ + Sbjct: 686 MVNELETSKSDLEAKISENSNEDKQQIEKLEESIKE 721 >UniRef50_A0EHN8 Cluster: Chromosome undetermined scaffold_97, whole genome shotgun sequence; n=1; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_97, whole genome shotgun sequence - Paramecium tetraurelia Length = 1252 Score = 157 bits (381), Expect = 2e-36 Identities = 246/1187 (20%), Positives = 506/1187 (42%), Gaps = 117/1187 (9%) Query: 445 KDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEK 504 + TL + Q QQ E + + + ++ + +QE KQ E + V L + Sbjct: 29 QSTLFNRDQQSVQQMREQIRQLKMQLSKTNLEKETAIQENNKQTRELERVQIYVTQLEAR 88 Query: 505 LKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEEL 564 +K EE + + + +A K + ++ H LKQ + D N E L ++ Sbjct: 89 IKMLEESL--IAQQTEAERK--LTLQKQHFEYLKQSTIERQSTGMQRDFNLEKNDLEIQI 144 Query: 565 HHLSQKVAELEEEKGNLQL--HLVDY-DSGRMIES-------------DVYKKMIEMEN- 607 L Q++ ELEE+ + H+ Y D R I+S ++KM EM+ Sbjct: 145 KLLKQRIVELEEQLQKVTSIDHMSGYEDLQRQIDSLTLQLMSQKGQERQFFEKMQEMQKQ 204 Query: 608 LAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQ 667 L T K L+ S K ++ + + + ++++D QL+ +++ +++ H Sbjct: 205 LQITTSKYDQLVHSSKLEIEEYVEKITLLSNQLKDSQDYTEQLEDEKLTQQLQLSH---- 260 Query: 668 IDALSASKKELALVIENLKLDKEQLY---GTIKDLENDKEDIMNKLQNYIQENMDLTDKL 724 A + L I+ +K++K+ + ++ LE+ + N+L N +N+ Sbjct: 261 -QVFLAYNEIERLQIKIVKINKKMKFIEESHVQQLEDRQHQFENQL-NLRSQNLQKGSNE 318 Query: 725 EKMSAE-KISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEE 783 K+S E KIS L ++ EQ Q + + K Q+ D + ++ E K K + E Sbjct: 319 LKISYELKISNLQLQLQEREQMIEQLKLELKQKQQKIDELTKQLDQERQKNKQQF----E 374 Query: 784 SIAV-MEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQL- 841 S V + D + + ++ +L + +++ + ++D ++NR+ +++ + QL Sbjct: 375 SFTVQIRDHKNTSDKAYAELQTNSRDQILKLQQQKQEQDSVLNRIKAELENQKTQNSQLQ 434 Query: 842 -----LEIEHENKELQKKNQIL---LEENQ-----------------NLQISLSDMQQHY 876 L+ E+E Q ++QI LE N+ LQ L QQ Y Sbjct: 435 NQINQLQSEYEYMRQQYESQIANLTLEINRLKTQLQQISGKSQQSLDELQYQLEASQQQY 494 Query: 877 NALVEKANRTDLAESESTK-YQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQ 935 L+E+ + + S+ + Y+ +++ L+ L + T++ L + KE E EFN+ Sbjct: 495 QQLIEQQQQLQNSVSKKNELYENEIKQLKQKLTQATNDLNNLKNESDKEKE----EFNST 550 Query: 936 IESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQK 995 ++ + +++ +K + ++QL+ LQ+ E+ + V +L ++ + + + +Q+ Sbjct: 551 LQDYSQQFQLMEKKLKDKENELSQLKKTLQQ---TTESYSEKVTQL-ELEINQLQQQLQQ 606 Query: 996 QQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTT 1055 Q TQ + + KL +K+++ EI L Q I + + +S E +L++ Sbjct: 607 QSTQFTSQLKNSEKDKEKLKQTIKERETEISQLKQTIKTMEENSTITISQLEIQLSKLQQ 666 Query: 1056 KLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIIS 1115 + +N ++E Q+ Q KQ + Q + E ++I E++ K E ++ E M+ S Sbjct: 667 QYQNSQQEQQQQKNQF--QKQIQQMTQT-INELKERISEIQLEKEQLENSL--NESMLKS 721 Query: 1116 STIEPMSDDANNVDXXXXXXXXXXXXLKVQEEE--EFIQERSVLQEQSAKLNTEL--QEC 1171 S D + +K +E + + Q+ LQE+ +L E+ QE Sbjct: 722 SNSN--KDLQRQIQLLQKQIQEYEIRIKFEENKGSDLNQQLESLQEELEQLKLEIKNQER 779 Query: 1172 YTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQR 1231 + ++ + + +L ++ Q+Q L+ KL + ++D+L + E + +Q Sbjct: 780 DKEKLKSQLKDQQLQYEQLLKQKQ--DLEQKLSIITQQHDDLTNEYNEFYMNQQQQQEQL 837 Query: 1232 GFEIAELWKQ--HLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTM 1289 I E KQ + Q+ F++ +L Q+ + E+ Q + K+ + Sbjct: 838 QGNIQEKDKQIKNANQQINQFKQKISDLERQIIQMTHEIEERDTKFSELEQNNSMKLQKL 897 Query: 1290 EQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXX 1349 Q + ++E L + K + +Q E E++ EKV Sbjct: 898 NNTIDQQKRQNQEDEKL--WKSKLTQLSDQHEERERELQQEKVDLQQKLEFQL------- 948 Query: 1350 XDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQL 1409 + + KQ EQ + + ++ QL+ S ND + K + + Q Sbjct: 949 ----NQLKKSKQETEQRLSQLQLKHDQLENS-------YEDIQREFNDLQDKYVIIQQQF 997 Query: 1410 ELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHEN 1469 EI Q ++ + +F+ ++ L E ++ L + +S LA + EN Sbjct: 998 SSLTIEI-QLLQKFKLDTNDNELKFQALKDSL---ESQLRLLQTKYDSLLASEQHLQDEN 1053 Query: 1470 ANHYETMQKESEIERVKLIEELNVKI-TESVSLNKQVAELNKALEEEVAKTNEMQTALEN 1528 + +++++ I R+K +E+ +K+ TE+VSL + + + +E AK ++ + Sbjct: 1054 ----KKLEEQNNI-RIKQLEDFRLKLDTETVSL-AEYETVKQERDESTAKNFQLSSQALK 1107 Query: 1529 QEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNT 1575 + E+ L EI NL++ ++ +++Q +FA + + Q + T Sbjct: 1108 DKSELQKLRREIENLKDDIKTKENEVQDAYNFAQSRQTTGNLQKNET 1154 Score = 124 bits (299), Expect = 2e-26 Identities = 228/1278 (17%), Positives = 537/1278 (42%), Gaps = 116/1278 (9%) Query: 222 QENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQX 281 Q++ M + + K +L K K+ I + + LE + ++ +++ LE+ Sbjct: 37 QQSVQQMREQIRQLKMQLSKTNLEKETAIQENNKQTRELERVQIYVTQLEARIKM-LEES 95 Query: 282 XXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANM--TELTKKIELLEHLNCQIR 339 L KQ E + E + G N+ +L +I+LL+ ++ Sbjct: 96 LIAQQTEAERKLTLQKQHFEYLKQSTIERQSTGMQRDFNLEKNDLEIQIKLLKQRIVELE 155 Query: 340 QTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTD 399 + +++ + G E S + + R KM+ QL T D Sbjct: 156 EQLQKVTSIDHMSGYEDLQRQIDSLTLQLMSQKGQERQFFEKMQEMQKQLQITTSKYDQL 215 Query: 400 KKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQH 459 +K EI + I L+ L D + + + + L QLQL HQ Sbjct: 216 VHSSKLEIEEYVEKITLLSNQLKDSQDYTEQLED------------EKLTQQLQLSHQVF 263 Query: 460 MEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQI-TQLNDE 518 + NEI ++Q ++ + +N ++K + + +++L+ + Q QLN Sbjct: 264 LA-------------YNEIERLQIKIVK-INKKMKFIE-ESHVQQLEDRQHQFENQLNLR 308 Query: 519 IDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEK 578 K ++K +++LK+ +Q ++ + + I +L EL QK+ EL + Sbjct: 309 SQNLQKGSNELKISYELKISNLQL------QLQEREQMIEQLKLELKQKQQKIDELTK-- 360 Query: 579 GNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYD 638 QL + + ES +++ + T KA + L++ D + +L +Q+ D Sbjct: 361 ---QLDQERQKNKQQFESFT----VQIRDHKNTSDKAYAELQTNSRDQILKLQQQKQEQD 413 Query: 639 EVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSAS----KKELALVIENLKLDKEQLYG 694 V +++ ++L++ + ++ L+ QI+ L + +++ I NL L+ +L Sbjct: 414 SVLNRIK--AELENQKT----QNSQLQNQINQLQSEYEYMRQQYESQIANLTLEINRLKT 467 Query: 695 TIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGID 754 ++ + + +++LQ ++ + +L + +++ ++K N +++I+ + Sbjct: 468 QLQQISGKSQQSLDELQYQLEASQQQYQQLIEQQ-QQLQNSVSKKNELYENEIKQ---LK 523 Query: 755 AKIQERDLYIENIESELSKYK----SRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQ 810 K+ + + N+++E K K S + + +ME + E + QL LQ+ Sbjct: 524 QKLTQATNDLNNLKNESDKEKEEFNSTLQDYSQQFQLMEKKLKDKENELSQLKKTLQQTT 583 Query: 811 KAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLS 870 ++YSE Q + +N+L + +++Q + + K +K + L + + + +S Sbjct: 584 ESYSEKVTQLELEINQL------QQQLQQQSTQFTSQLKNSEKDKEKLKQTIKERETEIS 637 Query: 871 DMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEI 930 ++Q + E + T ++ + QL L+ + E Q Q +K+I+ + Sbjct: 638 QLKQTIKTMEENSTIT------ISQLEIQLSKLQQQYQNSQQEQQQQKNQFQKQIQQMTQ 691 Query: 931 EFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELID 990 N +++ I + ++ E+ E ++ E+ L+ +N ++L ++ L K ++ + Sbjct: 692 TIN-ELKERISEIQLEKEQLENSLN-----ESMLKSSNSN-KDLQRQIQLLQKQ-IQEYE 743 Query: 991 KHVQKQQTQSPDYTEQYIN---EINKLNALLKQKDEEIIALNQKINNAQVSYMSMVS--- 1044 ++ ++ + D +Q + E+ +L +K ++ + L ++ + Q+ Y ++ Sbjct: 744 IRIKFEENKGSDLNQQLESLQEELEQLKLEIKNQERDKEKLKSQLKDQQLQYEQLLKQKQ 803 Query: 1045 DYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEM 1104 D E KL+ T + +++ E ++ +Q E+LQ ++E+D QIK + F+ Sbjct: 804 DLEQKLSIITQQHDDLTNEYNEF---YMNQQQQQEQLQGNIQEKDKQIKNANQQINQFKQ 860 Query: 1105 NIPKTEGMIISST--IEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSA 1162 I E II T IE + ++ Q++ + ++ + + + Sbjct: 861 KISDLERQIIQMTHEIEERDTKFSELEQNNSMKLQKLNNTIDQQKRQNQEDEKLWKSKLT 920 Query: 1163 KLNTELQECYTKIIQLETLNTELTGHDVVNQ--EQINQLKSKLEQLNTENDNLLSTVAEL 1220 +L+ + +E + +Q E ++ + +NQ + + + +L QL ++D L ++ ++ Sbjct: 921 QLSDQHEE-RERELQQEKVDLQQKLEFQLNQLKKSKQETEQRLSQLQLKHDQLENSYEDI 979 Query: 1221 RSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQ 1280 + + D+ + I + Q + + Q + + ++ + E K++ L DS++S + Sbjct: 980 QREFNDLQDK--YVIIQ---QQFSSLTIEIQLLQ-KFKLDTNDNELKFQALKDSLESQLR 1033 Query: 1281 EETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXX 1340 K + + + + LQD+ + L+E+ I Q+E R +++ E V+ Sbjct: 1034 LLQTK---YDSLLASEQHLQDEN---KKLEEQNNIRIKQLEDFRLKLDTETVSLAEYETV 1087 Query: 1341 XXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQ--LKKSSXXXXXXXXXXXXRVNDA 1398 + + +Q+ K E L EN + +K R Sbjct: 1088 KQERDESTAKNFQLSSQALKDKSELQKLRREIENLKDDIKTKENEVQDAYNFAQSRQTTG 1147 Query: 1399 EAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQ---LVEYEKRIEDLTYEK 1455 + E T L++++ ++ + + + +N+E + +++Q L +++ + + Sbjct: 1148 NLQKNE-TDMLKIENQKLLNQIKGFETKIIIQNEEIDKLKRQNEELTLQNSQLKKYSDKL 1206 Query: 1456 ESELAILRLKMHENANHY 1473 ++E +L ++ N Y Sbjct: 1207 QAEYDQCQLDYKDHINKY 1224 Score = 94.3 bits (224), Expect = 2e-17 Identities = 159/756 (21%), Positives = 333/756 (44%), Gaps = 80/756 (10%) Query: 143 DVTHLSN-TIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXX 201 D+ +L N + KEK+ S LQ + + L++K NE Q+ + + T Sbjct: 532 DLNNLKNESDKEKEEFNSTLQDYSQQFQLMEKKLKDKENELSQLKKTLQQTTESYSEKVT 591 Query: 202 XXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLE 261 + +QQ T+ F + + +K++L + I+ ++ IS L++ K +E Sbjct: 592 QLELEINQLQQQLQQQSTQ----FTSQLKNSEKDKEKLKQTIKERETEISQLKQTIKTME 647 Query: 262 AARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANM 321 ++ S+L +L + +Q + S +E+ + + + +I M Sbjct: 648 E---NSTITISQLEIQLSKL---------------QQQYQNSQQEQQQQKNQFQKQIQQM 689 Query: 322 TELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKG-SPLISRKSGRNTAS 380 T+ EL E ++ +I+ ++LEN L ES SS S K I + Sbjct: 690 TQTIN--ELKERIS-EIQLEKEQLENSL----NESMLKSSNSNKDLQRQIQLLQKQIQEY 742 Query: 381 KMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXX 440 +++ + + LNQ + + E+ +L++ I++ +D KE + S+ Sbjct: 743 EIRIKFEENKGSDLNQQLESL--QEELEQLKLEIKNQERD---KEKLKSQLKDQQLQYEQ 797 Query: 441 XXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLK---QELNDEIKDVN 497 K L +L + QQH + + N +N+ + QEQL+ QE + +IK+ N Sbjct: 798 LLKQKQDLEQKLSIITQQHDD----LTNEYNEFYMNQ-QQQQEQLQGNIQEKDKQIKNAN 852 Query: 498 --VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNK 555 + +K+ E QI Q+ EI+ + +++ N+ +KL+++ TID + + ++ Sbjct: 853 QQINQFKQKISDLERQIIQMTHEIEERDTKFSELEQNNSMKLQKLNNTIDQQKRQNQEDE 912 Query: 556 EI--VRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRL 613 ++ +LT+ ++ EL++EK +LQ L ++ ++ +S K + L++ +L Sbjct: 913 KLWKSKLTQLSDQHEERERELQQEKVDLQQKL-EFQLNQLKKS----KQETEQRLSQLQL 967 Query: 614 KAISLLESQKFDLVQELHILQQKYDEVEDKLA----DISQLQSDQVCSEIKSVHLEEQID 669 K LE+ D+ +E + LQ KY ++ + + +I LQ ++ + + + D Sbjct: 968 KH-DQLENSYEDIQREFNDLQDKYVIIQQQFSSLTIEIQLLQKFKLDTNDNELKFQALKD 1026 Query: 670 ALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSA 729 +L + + L ++L ++ L K LE + +L+++ +L K+ Sbjct: 1027 SLESQLRLLQTKYDSLLASEQHLQDENKKLEEQNNIRIKQLEDF---------RL-KLDT 1076 Query: 730 EKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVME 789 E +S LA+ +Q + ++ AK + +SEL K + I L++ I E Sbjct: 1077 ETVS--LAEYETVKQERDEST----AKNFQLSSQALKDKSELQKLRREIENLKDDIKTKE 1130 Query: 790 DR---RYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEH 846 + Y+ + G+ LQ+ + + I+ +L+N++ + +++ +++ Sbjct: 1131 NEVQDAYNFAQSRQTTGN-LQKNETDMLK--IENQKLLNQIKGFETKIIIQNEEIDKLKR 1187 Query: 847 ENKELQKKNQILLEENQNLQISLSDMQQHYNALVEK 882 +N+EL +N L + + LQ Q Y + K Sbjct: 1188 QNEELTLQNSQLKKYSDKLQAEYDQCQLDYKDHINK 1223 Score = 83.8 bits (198), Expect = 4e-14 Identities = 182/895 (20%), Positives = 396/895 (44%), Gaps = 85/895 (9%) Query: 92 ESLANTLKQKEI----LMEKIKQYKELSKR---SSTTIVRXXXXXXXXXXXXXXXQLGD- 143 E L LKQK+ L +++ Q ++ +K+ S T +R D Sbjct: 342 EQLKLELKQKQQKIDELTKQLDQERQKNKQQFESFTVQIRDHKNTSDKAYAELQTNSRDQ 401 Query: 144 VTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXX 203 + L +E+D+ L+ ++ +++ +T LQ +IN+ ++++ + Sbjct: 402 ILKLQQQKQEQDSVLNRIKAELENQKTQNSQLQNQINQ----LQSEYEYMRQQYESQIAN 457 Query: 204 XXXXXXXXEDTKQQMT-KMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEA 262 + QQ++ K Q++ ++ + + +Q+ + IE + +S+ + N+L E Sbjct: 458 LTLEINRLKTQLQQISGKSQQSLDELQYQLEASQQQYQQLIEQQQQLQNSVSKKNELYEN 517 Query: 263 ARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMT 322 EI KL Q +++ ++ +E+K + ++ Sbjct: 518 ---EIKQLKQKLTQATNDLNNLKNESDKEKEEF-NSTLQDYSQQFQLMEKKLKDKENELS 573 Query: 323 ELTKKI-ELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASK 381 +L K + + E + ++ Q E+ + +S +S K ++ + T + Sbjct: 574 QLKKTLQQTTESYSEKVTQLELEINQLQQQLQQQSTQFTSQLKNSEK--DKEKLKQTIKE 631 Query: 382 MKSPWSQLSS--ETLNQDTDKKINKNEI--AKLEMVIQSLNKDLVDKEYVISEKDTXXXX 437 ++ SQL +T+ +++ I++ EI +KL+ Q+ ++ ++ ++ Sbjct: 632 RETEISQLKQTIKTMEENSTITISQLEIQLSKLQQQYQNSQQEQQQQKNQFQKQIQQMTQ 691 Query: 438 XXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDV-NEIAKVQEQLKQ-ELNDEIKD 495 + + I QL+ E ++ S++ + +D+ +I +Q+Q+++ E+ + ++ Sbjct: 692 TINELKERISEI-QLEKEQLENSLNESMLKSSNSNKDLQRQIQLLQKQIQEYEIRIKFEE 750 Query: 496 VNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKS---NHKLKLKQMQKTIDNF-SKVS 551 DL ++L+S +E++ QL EI ++ K+KS + +L+ +Q+ K + K+S Sbjct: 751 NKGSDLNQQLESLQEELEQLKLEIKNQERDKEKLKSQLKDQQLQYEQLLKQKQDLEQKLS 810 Query: 552 DSNKEIVRLTEELHHLSQKVAELEEE-KGNLQLHLVDY-DSGRMIE------SDVYKKMI 603 ++ LT E + + +E+ +GN+Q ++ + I SD+ +++I Sbjct: 811 IITQQHDDLTNEYNEFYMNQQQQQEQLQGNIQEKDKQIKNANQQINQFKQKISDLERQII 870 Query: 604 EMENLAETRLKAISLLESQKFDLVQELH--ILQQKYDEVED------KLADIS------- 648 +M + E R S LE +Q+L+ I QQK ED KL +S Sbjct: 871 QMTHEIEERDTKFSELEQNNSMKLQKLNNTIDQQKRQNQEDEKLWKSKLTQLSDQHEERE 930 Query: 649 -QLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIM 707 +LQ ++V + K LE Q++ L SK+E + L+L +QL + +D++ + D+ Sbjct: 931 RELQQEKVDLQQK---LEFQLNQLKKSKQETEQRLSQLQLKHDQLENSYEDIQREFNDLQ 987 Query: 708 NKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQT-QFGIDAKIQERDLYIEN 766 +K Q+ LT +++ + K+ ++ + K Q + ++++++ ++ Sbjct: 988 DKYVIIQQQFSSLTIEIQLLQKFKLD------TNDNELKFQALKDSLESQLRLLQTKYDS 1041 Query: 767 IESELSKYKSRICRLEES----IAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDE 822 + + + +LEE I +ED R L+ + L Y KQ+ E T + + Sbjct: 1042 LLASEQHLQDENKKLEEQNNIRIKQLEDFRLKLDTETVSLAEYETVKQER-DESTAKNFQ 1100 Query: 823 LVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEK 882 L ++ L D E Q L E EN K+ I +EN+ +Q + + Q + Sbjct: 1101 LSSQ--ALKDKS---ELQKLRREIEN----LKDDIKTKENE-VQDAYNFAQSRQTTGNLQ 1150 Query: 883 ANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIE 937 N TD+ + E+ K Q++ E+ + I +E I + K++ E+L ++ N+Q++ Sbjct: 1151 KNETDMLKIENQKLLNQIKGFETKI-IIQNEE---IDKLKRQNEELTLQ-NSQLK 1200 Score = 59.3 bits (137), Expect = 9e-07 Identities = 99/551 (17%), Positives = 217/551 (39%), Gaps = 49/551 (8%) Query: 1059 NMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTI 1118 N +E S + +KQ + L +++++E +M + KT + + I Sbjct: 7 NEKEPYSLFSPSVNLNKQSDNTQSTLFNRDQQSVQQMREQIRQLKMQLSKTN-LEKETAI 65 Query: 1119 EPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQL 1178 + + ++ +K+ EE + Q+ A+ LQ+ + + ++ Sbjct: 66 QENNKQTRELERVQIYVTQLEARIKMLEES------LIAQQTEAERKLTLQKQHFEYLKQ 119 Query: 1179 ETLNTELTGHDVVNQEQINQLKSKLE-QLNTENDNLLSTVAELRSSISSAVDQRGFE--- 1234 T+ + TG Q N K+ LE Q+ ++ +L+ ++S G+E Sbjct: 120 STIERQSTGM----QRDFNLEKNDLEIQIKLLKQRIVELEEQLQK-VTSIDHMSGYEDLQ 174 Query: 1235 --IAELWKQHLAQR--EADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTME 1290 I L Q ++Q+ E F + E++ QL SKY+QL+ S + +E +E Sbjct: 175 RQIDSLTLQLMSQKGQERQFFEKMQEMQKQLQITTSKYDQLVHSSKLEIEEY------VE 228 Query: 1291 QVTSLQNKLQDKEEHLRNLQEK----YADVINQIEILRSEIEDEKVAFXXXXXXXXXXXX 1346 ++T L N+L+D +++ L+++ + +Q+ + +EIE ++ Sbjct: 229 KITLLSNQLKDSQDYTEQLEDEKLTQQLQLSHQVFLAYNEIERLQIKIVKINKKMKFIEE 288 Query: 1347 XXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXR-----------V 1395 L ++ N+ + + +LK S + Sbjct: 289 SHVQQLEDRQHQFENQLNLRSQNLQKGSNELKISYELKISNLQLQLQEREQMIEQLKLEL 348 Query: 1396 NDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEK-RIEDLTYE 1454 + K+ ELT QL+ + + Q+ +T+ + + + +L + +I L + Sbjct: 349 KQKQQKIDELTKQLDQERQKNKQQFESFTVQIRDHKNTSDKAYAELQTNSRDQILKLQQQ 408 Query: 1455 KESELAIL-RLKMHENANHYETMQKESEIERVKLIEELNVKITES--VSLNKQVAELNKA 1511 K+ + ++L R+K + Q +++I +++ E + ES +L ++ L Sbjct: 409 KQEQDSVLNRIKAELENQKTQNSQLQNQINQLQSEYEYMRQQYESQIANLTLEINRLKTQ 468 Query: 1512 LEEEVAKT----NEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQG 1567 L++ K+ +E+Q LE + + L ++ LQN V + + + Sbjct: 469 LQQISGKSQQSLDELQYQLEASQQQYQQLIEQQQQLQNSVSKKNELYENEIKQLKQKLTQ 528 Query: 1568 RDEQLDNTMNK 1578 L+N N+ Sbjct: 529 ATNDLNNLKNE 539 >UniRef50_Q02224 Cluster: Centromeric protein E; n=8; Eutheria|Rep: Centromeric protein E - Homo sapiens (Human) Length = 2663 Score = 157 bits (381), Expect = 2e-36 Identities = 269/1344 (20%), Positives = 582/1344 (43%), Gaps = 122/1344 (9%) Query: 298 QSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGT--E 355 Q +E K E+ + +I + E + LE++ + + + +E+ T + Sbjct: 571 QDLENELSSKVELLREKEDQIKKLQEYIDS-QKLENIKMDLSYSLESIEDPKQMKQTLFD 629 Query: 356 SKAVSSPSKKGSPLISRKSGRNTASKMK---SPWSQLSSETLNQDTDKKINKNEIAKLEM 412 ++ V+ +K+ S + R KMK + + Q+ ++ + + K LE Sbjct: 630 AETVALDAKRESAFL-RSENLELKEKMKELATTYKQMENDIQLYQSQLEAKKKMQVDLEK 688 Query: 413 VIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHME-GPSLIHVGTN 471 +QS ++ +I K GK I LQ E + +E +L Sbjct: 689 ELQSAFNEITKLTSLIDGKVPKDLLCNLELEGK---ITDLQKELNKEVEENEALREEVIL 745 Query: 472 TEDVNEIAKVQEQLKQELNDEIKDVNV----KD-LIEKLKSAEEQITQLNDEIDAANKNM 526 ++ + E+L++E+ D+ +++++ KD L ++ E ++ L +EI ++ Sbjct: 746 LSELKSLPSEVERLRKEIQDKSEELHIITSEKDKLFSEVVHKESRVQGLLEEIGKTKDDL 805 Query: 527 IKVKSNHKLKLKQMQ--KTI--DNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQ 582 +SN+K ++ Q KT+ D K +E R+ +E+ +LS++ + + G L+ Sbjct: 806 ATTQSNYKSTDQEFQNFKTLHMDFEQKYKMVLEENERMNQEIVNLSKEAQKFDSSLGALK 865 Query: 583 LHLVDYDSGRMIES--DVYKKMIEMENLAE---TRLKAISLLESQKFDLVQELHILQQKY 637 L Y + + E +V +++ EME L E R + +E +K + ++L ++ Sbjct: 866 TEL-SYKTQELQEKTREVQERLNEMEQLKEQLENRDSPLQTVEREKTLITEKLQQTLEEV 924 Query: 638 DEVEDKLADISQLQSD-QVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTI 696 + + D+ QLQ Q+ + + + ++ ++++L +E+LK +E + T+ Sbjct: 925 KTLTQEKDDLKQLQESLQIERDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQETI-NTL 983 Query: 697 KDLENDK-------EDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQT 749 K +++ E+ + ++ Q+ M DK + + A+ L A + E I+ Sbjct: 984 KSKISEEVSRNLHMEENTGETKDEFQQKMVGIDKKQDLEAKNTQTLTADVKDNEI--IEQ 1041 Query: 750 QFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEK 809 Q I + IQE++ + +ES +++ + L+E+I + + + L D+L + Sbjct: 1042 QRKIFSLIQEKNELQQMLESVIAEKEQLKTDLKENIEMTIENQEELRLLGDELKKQQEIV 1101 Query: 810 QKAYSEYTIQEDEL---VNRLAVLMDH-----DRVVEKQ--LLEIEHENKELQKK-NQI- 857 + + +E EL +RLA + + ++ EKQ LL ++ E E+QKK N+I Sbjct: 1102 AQEKNHAIKKEGELSRTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEIE 1161 Query: 858 -LLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESN-------LKR 909 L E +N +++L M+ L +K N TK + L++L+ + L+ Sbjct: 1162 NLKNELKNKELTLEHMETERLELAQKLNENYEEVKSITKERKVLKELQKSFETERDHLRG 1221 Query: 910 ITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEK--NIEYVTQLEAQLQE- 966 E + +Q K+E++ I E+ ++ ++EK + N + + + +LQE Sbjct: 1222 YIREIEATGLQTKEELKIAHIHLKEHQETIDELRRSVSEKTAQIINTQDLEKSHTKLQEE 1281 Query: 967 --YKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKL--NALLKQKD 1022 + + L NV+++++ + + + +Q+ + D T E+ +L N ++ Sbjct: 1282 IPVLHEEQELLPNVKKVSETQETMNELELLTEQSTTKDSTTLARIEMERLRLNEKFQESQ 1341 Query: 1023 EEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQ 1082 EEI +L ++ +N + ++ ++ L ++E + +Q L+ K+ + E Sbjct: 1342 EEIKSLTKERDNLKTIKEALEVKHDQLKEHIRETLAKIQESQSK-QEQSLNMKEKDNETT 1400 Query: 1083 ILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXL 1142 +V E + Q K L E+ E + +S ++ D+ +V Sbjct: 1401 KIVSEME-QFKPKDSALLRIEI-----EMLGLSKRLQESHDEMKSV-------------- 1440 Query: 1143 KVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQ--INQLK 1200 +E+++ + + VLQ +S +L ++E K LET H + +++ IN+L+ Sbjct: 1441 -AKEKDDLQRLQEVLQSESDQLKENIKEIVAK--HLETEEELKVAHCCLKEQEETINELR 1497 Query: 1201 SKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQ 1260 L + TE +ST+ + +I+ + + EI E +Q ++ ++ Q+ +EL+ Q Sbjct: 1498 VNLSEKETE----ISTIQKQLEAINDKLQNKIQEIYEKEEQLNIKQISEVQENVNELK-Q 1552 Query: 1261 LSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQI 1320 + L S++S E TN++ E +Q +++KEE ++ +QE +Q+ Sbjct: 1553 FKEHRKAKDSALQSIESKMLELTNRL--QESQEEIQIMIKEKEE-MKRVQEALQIERDQL 1609 Query: 1321 -----EILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENA 1375 EI+ E ++ + ++ + + + Q+ ++ NI EN Sbjct: 1610 KENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQF-ETQKLNLENIETENI 1668 Query: 1376 QLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFE 1435 +L + +D + + L+++ ++ + E ++ +E + Sbjct: 1669 RLTQILHENLEEMRSVTKERDDLRS----VEETLKVERDQLKENLRETITRDLEKQEELK 1724 Query: 1436 NVRQQLVEYEKRIEDL---TYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELN 1492 V L E+++ I+ L EK +E++ M ++ H K ++ K+ EEL Sbjct: 1725 IVHMHLKEHQETIDKLRGIVSEKTNEIS----NMQKDLEHSNDALKAQDL---KIQEELR 1777 Query: 1493 VKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEI-TNLQNMV--RA 1549 + + + +L + E+ K + MQ LEN ++ E+ N ++ + Sbjct: 1778 IAHMHLKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQELKANEHQLITLKK 1837 Query: 1550 SSSKIQKHVSFASD-TKQGRDEQL 1572 ++ QK VS KQ +D+ L Sbjct: 1838 DVNETQKKVSEMEQLKKQIKDQSL 1861 Score = 140 bits (339), Expect = 3e-31 Identities = 239/1313 (18%), Positives = 573/1313 (43%), Gaps = 106/1313 (8%) Query: 328 IELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWS 387 +E E +N +I +KE + +++G +S +++ + K+ R ++ Sbjct: 837 LEENERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQE----LQEKT-REVQERLNE-ME 890 Query: 388 QLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDT 447 QL + N+D+ + + E ++ + L + L + + + EKD +D Sbjct: 891 QLKEQLENRDSPLQTVEREKT---LITEKLQQTLEEVKTLTQEKDDLKQLQESLQIERDQ 947 Query: 448 L------IAQLQLEHQQHMEGPSLIHVGTNTEDVNEI-AKVQEQLKQELNDEIKDVNVKD 500 L + ++ Q+ + +L + + E +N + +K+ E++ + L+ E KD Sbjct: 948 LKSDIHDTVNMNIDTQEQLRN-ALESLKQHQETINTLKSKISEEVSRNLHMEENTGETKD 1006 Query: 501 L-------IEKLKSAEEQITQL-------NDEIDAANKNMIKVKSNHKLKLKQMQKTIDN 546 I+K + E + TQ N+ I+ K ++ ++L+ + ++ I Sbjct: 1007 EFQQKMVGIDKKQDLEAKNTQTLTADVKDNEIIEQQRKIFSLIQEKNELQ-QMLESVIAE 1065 Query: 547 FSKVSDSNKEIVRLT----EELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKM 602 ++ KE + +T EEL L ++ + +E + H + + G + S ++ Sbjct: 1066 KEQLKTDLKENIEMTIENQEELRLLGDELKKQQEIVAQEKNHAIKKE-GEL--SRTCDRL 1122 Query: 603 IEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVED-------KLADISQLQSDQV 655 E+E + + + + + Q ++ +E+ +Q+K +E+E+ K + ++++++ Sbjct: 1123 AEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKNKELTLEHMETERL 1182 Query: 656 CSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLE----NDKEDIMNKLQ 711 K E++ +++ +K L + ++ + +++ L G I+++E KE++ K+ Sbjct: 1183 ELAQKLNENYEEVKSITKERKVLKELQKSFETERDHLRGYIREIEATGLQTKEEL--KIA 1240 Query: 712 N-YIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESE 770 + +++E+ + D+L + +EK +++ IN ++ K T K+QE ++ + + E E Sbjct: 1241 HIHLKEHQETIDELRRSVSEKTAQI---INTQDLEKSHT------KLQE-EIPVLHEEQE 1290 Query: 771 LSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVL 830 L ++ +E++ +E K + ++ ++ +E + E + L Sbjct: 1291 LLPNVKKVSETQETMNELELLTEQSTTKDSTTLARIEMERLRLNEKFQESQEEIKSLTKE 1350 Query: 831 MDHDRVVEKQLLEIEHEN-KELQKKNQILLEENQNLQISLSDMQQHYNA---LVEKANRT 886 D+ + + K+ LE++H+ KE ++ ++E+Q+ Q +M++ N +V + + Sbjct: 1351 RDNLKTI-KEALEVKHDQLKEHIRETLAKIQESQSKQEQSLNMKEKDNETTKIVSEMEQF 1409 Query: 887 DLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVL 946 +S + + ++ L L+ +H+ + ++K +++ L+ ++ + + K + Sbjct: 1410 KPKDSALLRIEIEMLGLSKRLQE-SHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEI 1468 Query: 947 NEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQ 1006 K+ + E + L+E + I L +N+ E + + I K ++ + + ++ Sbjct: 1469 VAKHLETEEELKVAHCCLKEQEETINELRVNLSE-KETEISTIQKQLEAINDKLQNKIQE 1527 Query: 1007 YINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQR 1066 + +LN + +E + ++ + + S + ESK+ + T +L+ +EE+Q Sbjct: 1528 IYEKEEQLNIKQISEVQENVNELKQFKEHRKAKDSALQSIESKMLELTNRLQESQEEIQI 1587 Query: 1067 VSKQLLDSKQHNEELQILVREQDDQIKE-LKETKLTFEMNIPKTEGMIISSTIEPMSDDA 1125 + K+ + K+ E LQI + DQ+KE KE + + K + + + + Sbjct: 1588 MIKEKEEMKRVQEALQI----ERDQLKENTKEIVAKMKESQEKEYQFLKMTAVNETQEKM 1643 Query: 1126 NNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTEL 1185 ++ L+ E E I+ +L E ++ + +E ETL E Sbjct: 1644 CEIEHLKEQFETQKLNLENIETEN-IRLTQILHENLEEMRSVTKERDDLRSVEETLKVER 1702 Query: 1186 TGHDVVNQEQINQLKSKLEQLNTENDNLLS---TVAELRSSISSAVDQRGFEIAELWKQH 1242 +E I + K E+L + +L T+ +LR +S ++ +L + Sbjct: 1703 DQLKENLRETITRDLEKQEELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSN 1762 Query: 1243 LAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQN-KLQD 1301 A + D K + ELR+ + + E + D ++ E+T+K+ M++ N KLQ+ Sbjct: 1763 DALKAQDL-KIQEELRIAHMHLKEQQETI-DKLRGIVSEKTDKLSNMQKDLENSNAKLQE 1820 Query: 1302 KEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQ 1361 K + L+ + + + + + ++ + + +L + ++ Sbjct: 1821 KIQELKANEHQLITLKKDVNETQKKVSEMEQLKKQIKDQSLTLSKLEIENLNLAQELHEN 1880 Query: 1362 MQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTH 1421 ++E ++ +E L++ + + +A+ LE+ Q ELK + + K H Sbjct: 1881 LEEMK--SVMKERDNLRRVEETLKLERDQLKESLQETKARDLEI--QQELKTARMLSKEH 1936 Query: 1422 EYTI-----TLTQRNDEFENVRQQL----VEYEKRIEDLTYEKESELAILRLKMHENANH 1472 + T+ ++++ + ++++ L E +K+I++L ++ EL +LR+K N +H Sbjct: 1937 KETVDKLREKISEKTIQISDIQKDLDKSKDELQKKIQEL---QKKELQLLRVKEDVNMSH 1993 Query: 1473 YETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIE 1532 +K +E+E++K E N + + +L+++LEE E +E Sbjct: 1994 ----KKINEMEQLKKQFEPNYLCKCEMDNFQLTKKLHESLEEIRIVAKERDELRRIKESL 2049 Query: 1533 IVTLNDEITNLQNMVR--ASSSKIQKHVSFASDTKQGRDEQLDNTMN--KELL 1581 + + I L+ M+ + +++ SD +Q E L + KELL Sbjct: 2050 KMERDQFIATLREMIARDRQNHQVKPEKRLLSDGQQHLMESLREKCSRIKELL 2102 Score = 121 bits (291), Expect = 2e-25 Identities = 268/1319 (20%), Positives = 574/1319 (43%), Gaps = 175/1319 (13%) Query: 105 MEKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNALSVL--Q 162 ME++K+ E ++ S V ++ +T + +K+ +L + Q Sbjct: 889 MEQLKEQLE-NRDSPLQTVEREKTLITEKLQQTLEEVKTLTQEKDDLKQLQESLQIERDQ 947 Query: 163 VKMKIMETTIL--DLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTK 220 +K I +T + D QE++ + ++ + E+T + + Sbjct: 948 LKSDIHDTVNMNIDTQEQLRNALESLKQHQETINTLKSKISEEVSRNLHMEENTGETKDE 1007 Query: 221 MQENFIAMEAEWKDEKQRLLKDIESKDVRISSLE-EANKLLEAARFEISLEHSKLAQELE 279 Q+ + + D+KQ D+E+K+ + + + + N+++E R SL K EL+ Sbjct: 1008 FQQKMVGI-----DKKQ----DLEAKNTQTLTADVKDNEIIEQQRKIFSLIQEK--NELQ 1056 Query: 280 QXXXXXXXXXXXXXXLAKQSIEPSCEEKTEI-----EEKGSLEIANMT---------ELT 325 Q K++IE + E + E+ E K EI EL+ Sbjct: 1057 QMLESVIAEKEQLKTDLKENIEMTIENQEELRLLGDELKKQQEIVAQEKNHAIKKEGELS 1116 Query: 326 KKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSP 385 + + L + ++++ +++L+ K + + +S KK + + + K N + Sbjct: 1117 RTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEIENLK---NELKNKELT 1173 Query: 386 WSQLSSETLNQDTDKKINKN-----EIAKLEMVIQSLNKDL-VDKEYVISEKDTXXXXXX 439 + +E L + +K+N+N I K V++ L K +++++ + Sbjct: 1174 LEHMETERL--ELAQKLNENYEEVKSITKERKVLKELQKSFETERDHL---RGYIREIEA 1228 Query: 440 XXXXGKDTL-IAQLQL-EHQQHM-EGPSLIHVGT----NTEDVNEI-AKVQEQL-----K 486 K+ L IA + L EHQ+ + E + T NT+D+ + K+QE++ + Sbjct: 1229 TGLQTKEELKIAHIHLKEHQETIDELRRSVSEKTAQIINTQDLEKSHTKLQEEIPVLHEE 1288 Query: 487 QELNDEIKDVN-VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTID 545 QEL +K V+ ++ + +L+ EQ T D A M +++ N K + + Q+ I Sbjct: 1289 QELLPNVKKVSETQETMNELELLTEQSTT-KDSTTLARIEMERLRLNEKFQ--ESQEEIK 1345 Query: 546 NFSKVSDSNKEIVRLTEELH-----HLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYK 600 + +K D+ K I E H H+ + +A+++E + + L + + +++ K Sbjct: 1346 SLTKERDNLKTIKEALEVKHDQLKEHIRETLAKIQESQSKQEQSL----NMKEKDNETTK 1401 Query: 601 KMIEMENLAETRLKAISLLESQKFDL---VQELHILQQKYDEVED---KLADISQLQSDQ 654 + EME + + A+ +E + L +QE H + + +D +L ++ Q +SDQ Sbjct: 1402 IVSEMEQF-KPKDSALLRIEIEMLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQ 1460 Query: 655 VCSEIKSV---HLE--EQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNK 709 + IK + HLE E++ KE I L+++ + I ++ E I +K Sbjct: 1461 LKENIKEIVAKHLETEEELKVAHCCLKEQEETINELRVNLSEKETEISTIQKQLEAINDK 1520 Query: 710 LQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIES 769 LQN IQE + +K E+++ ++ISE+ +N +Q K + +D +++IES Sbjct: 1521 LQNKIQE---IYEKEEQLNIKQISEVQENVNELKQFKEHRK--------AKDSALQSIES 1569 Query: 770 ELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAV 829 ++ + +R+ +E I +M + ++R + L Q ++ E T E+V + Sbjct: 1570 KMLELTNRLQESQEEIQIMIKEKEEMKRVQEAL----QIERDQLKENT---KEIVAK--- 1619 Query: 830 LMDHDRVVEKQLLEIEHENKELQKKNQI--LLEENQNLQISLSDMQQHYNALVEKANRTD 887 M + E Q L++ N+ +K +I L E+ + +++L +++ N + + + Sbjct: 1620 -MKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQKLNLENIETE-NIRLTQILHEN 1677 Query: 888 LAESES-TKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVL 946 L E S TK + LR +E LK V++ + E+L +E + K++ Sbjct: 1678 LEEMRSVTKERDDLRSVEETLK----------VERDQLKENLRETITRDLEKQ-EELKIV 1726 Query: 947 NEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQ 1006 + +++ E + +L + E N I N+ ++E N L+ D +Q++ + + ++ Sbjct: 1727 HMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDA-LKAQDLKIQEELRIAHMHLKE 1785 Query: 1007 YINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQR 1066 I+KL ++ +K + K++N Q D E+ A KL+ +E++ Sbjct: 1786 QQETIDKLRGIVSEKTD-------KLSNMQ-------KDLENSNA----KLQEKIQELKA 1827 Query: 1067 VSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDAN 1126 QL+ K+ E Q V E + K++K+ LT ++ + E + ++ + ++ Sbjct: 1828 NEHQLITLKKDVNETQKKVSEMEQLKKQIKDQSLT--LSKLEIENLNLAQELHENLEEMK 1885 Query: 1127 NVDXXXXXXXXXXXXLKVQEEE--EFIQE---RSVLQEQSAK----LNTELQECYTKI-- 1175 +V LK++ ++ E +QE R + +Q K L+ E +E K+ Sbjct: 1886 SVMKERDNLRRVEETLKLERDQLKESLQETKARDLEIQQELKTARMLSKEHKETVDKLRE 1945 Query: 1176 ------IQLETLNTELTGHDVVNQEQINQL-KSKLEQLNTEND-NL----LSTVAELRSS 1223 IQ+ + +L Q++I +L K +L+ L + D N+ ++ + +L+ Sbjct: 1946 KISEKTIQISDIQKDLDKSKDELQKKIQELQKKELQLLRVKEDVNMSHKKINEMEQLKKQ 2005 Query: 1224 IS----SAVDQRGFEIAELWKQHL------AQREADFQKTEHELRVQLSAFESKYEQLLD 1273 + F++ + + L A+ + ++ + L+++ F + +++ Sbjct: 2006 FEPNYLCKCEMDNFQLTKKLHESLEEIRIVAKERDELRRIKESLKMERDQFIATLREMIA 2065 Query: 1274 SVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEIL-RSEIEDEK 1331 + + Q + K + + L L++K ++ L ++Y+++ + E L R ++ EK Sbjct: 2066 RDRQNHQVKPEKRLLSDGQQHLMESLREKCSRIKELLKRYSEMDDHYECLNRLSLDLEK 2124 Score = 111 bits (267), Expect = 2e-22 Identities = 234/1125 (20%), Positives = 487/1125 (43%), Gaps = 131/1125 (11%) Query: 473 EDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSN 532 E+V+ + Q K +L +++ KDL++K+++ E+I L + ++ ++ + Sbjct: 360 EEVSLETRAQAMEKDQLAQLLEE---KDLLQKVQN--EKIENLTRMLVTSSSLTLQQELK 414 Query: 533 HKLKLKQMQKTIDNFSKVSDSNKEI-----VRLTEELHHLS-QKVAELEEEK-GNLQLHL 585 K K +++ + +K+ +SN +T + H LS + E++E + Sbjct: 415 AKRK-RRVTWCLGKINKMKNSNYADQFNIPTNITTKTHKLSINLLREIDESVCSESDVFS 473 Query: 586 VDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLA 645 D+ IE + K++ EN+ E+ L + L + +LV + L+ + +E+E KL Sbjct: 474 NTLDTLSEIEWNPATKLLNQENI-ESELNS---LRADYDNLVLDYEQLRTEKEEMELKLK 529 Query: 646 DISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKED 705 + + L + E Q+ ++ K L E D E + +L +KED Sbjct: 530 EKNDLDEFEALERKTKKDQEMQLIHEISNLKNLVKHREVYNQDLENELSSKVELLREKED 589 Query: 706 IMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQF-----GIDAKIQER 760 + KLQ YI + KLE + + +S L I +Q K QT F +DAK + Sbjct: 590 QIKKLQEYID-----SQKLENIKMD-LSYSLESIEDPKQMK-QTLFDAETVALDAKRESA 642 Query: 761 DLYIENIE--SELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTI 818 L EN+E ++ + + ++E I + + + LE K +E Q A++E T Sbjct: 643 FLRSENLELKEKMKELATTYKQMENDIQLYQSQ---LEAKKKMQVDLEKELQSAFNEIT- 698 Query: 819 QEDELVNRLAVLMDHDRVVEKQLLEIEHENK--ELQKKNQILLEENQNLQ---ISLSDMQ 873 +L L+D +V + L +E E K +LQK+ +EEN+ L+ I LS+++ Sbjct: 699 -------KLTSLID-GKVPKDLLCNLELEGKITDLQKELNKEVEENEALREEVILLSELK 750 Query: 874 QHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTL---IVQKKKEIEDLEI 930 SE + + +++D L IT E L +V K+ ++ L Sbjct: 751 S--------------LPSEVERLRKEIQDKSEELHIITSEKDKLFSEVVHKESRVQGLLE 796 Query: 931 EFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELID 990 E +D + K+ + QE++ N + L+M+ E+ KM LE + Sbjct: 797 EI-----GKTKDDLATTQSNYKSTD---------QEFQ-NFKTLHMDFEQKYKMVLEENE 841 Query: 991 KHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKL 1050 + Q+ S + +++ + + L L K +E L +K Q ++ + + +L Sbjct: 842 RMNQEIVNLSKE-AQKFDSSLGALKTELSYKTQE---LQEKTREVQ-ERLNEMEQLKEQL 896 Query: 1051 AQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTE 1110 + L+ +E E ++++L +Q EE++ L +E+DD +K+L+E+ L E + K++ Sbjct: 897 ENRDSPLQTVEREKTLITEKL---QQTLEEVKTLTQEKDD-LKQLQES-LQIERDQLKSD 951 Query: 1111 GMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQE 1170 + + N LK + EE + ++E + + E Q+ Sbjct: 952 IHDTVNMNIDTQEQLRNALESLKQHQETINTLKSKISEE-VSRNLHMEENTGETKDEFQQ 1010 Query: 1171 CYTKIIQ---LETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSA 1227 I + LE NT+ DV + E I Q + + +N+ + ++ S+ + Sbjct: 1011 KMVGIDKKQDLEAKNTQTLTADVKDNEIIEQQRKIFSLIQEKNE-----LQQMLESVIAE 1065 Query: 1228 VDQRGFEIAELWKQHLA-QREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKI 1286 +Q ++ E + + Q E E + + ++ A E + + S T + ++ Sbjct: 1066 KEQLKTDLKENIEMTIENQEELRLLGDELKKQQEIVAQEKNHAIKKEGELSRTCDRLAEV 1125 Query: 1287 VTMEQVTSLQNKLQDKEEHLRNLQEKYADV---INQIEILRSEIEDEKVAFXXXXXXXXX 1343 E++ +LQ+K++ L N+QE+ +++ IN+IE L++E++++++ Sbjct: 1126 --EEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKNKELTLEHMETERLE 1183 Query: 1344 XXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVL 1403 + N++Y++++ +I +E LK+ + + EA L Sbjct: 1184 LA-------QKLNENYEEVK-----SITKERKVLKELQKSFETERDHLRGYIREIEATGL 1231 Query: 1404 ELTHQLELKDSEIYQKTHEYTI-----TLTQRNDEFENVRQQLVEYEKRIEDLTYEKESE 1458 + ELK + I+ K H+ TI +++++ + N + + K E++ E + Sbjct: 1232 QTKE--ELKIAHIHLKEHQETIDELRRSVSEKTAQIINTQDLEKSHTKLQEEIPVLHEEQ 1289 Query: 1459 LAILRLK----MHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEE 1514 + +K E N E + ++S + + + + E + LN++ E + ++ Sbjct: 1290 ELLPNVKKVSETQETMNELELLTEQSTTKDSTTLARIEM---ERLRLNEKFQESQEEIKS 1346 Query: 1515 EVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVS 1559 + + ++T E E++ L + I ++ S SK ++ ++ Sbjct: 1347 LTKERDNLKTIKEALEVKHDQLKEHIRETLAKIQESQSKQEQSLN 1391 Score = 106 bits (255), Expect = 4e-21 Identities = 205/1020 (20%), Positives = 437/1020 (42%), Gaps = 108/1020 (10%) Query: 140 QLGDVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXX 199 Q+ +V N +K+ ++ +E+ +L+L ++ E + I+ K Sbjct: 1539 QISEVQENVNELKQFKEHRKAKDSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRV 1598 Query: 200 XXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKL 259 E+TK+ + KM+E+ E E++ K + + + K I L+E + Sbjct: 1599 QEALQIERDQLKENTKEIVAKMKES---QEKEYQFLKMTAVNETQEKMCEIEHLKEQFET 1655 Query: 260 LEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLA---------KQSIEPSCEEKT-- 308 + I E+ +L Q L + L + ++ + E Sbjct: 1656 QKLNLENIETENIRLTQILHENLEEMRSVTKERDDLRSVEETLKVERDQLKENLRETITR 1715 Query: 309 EIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSP 368 ++E++ L+I +M L + E ++ L + + E+ N + + A+ + K Sbjct: 1716 DLEKQEELKIVHM-HLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQE 1774 Query: 369 LIS-----RKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQ-------- 415 + K + T K++ S+ + + N D + N AKL+ IQ Sbjct: 1775 ELRIAHMHLKEQQETIDKLRGIVSEKTDKLSNMQKDLE---NSNAKLQEKIQELKANEHQ 1831 Query: 416 --SLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTL-IAQLQLEHQQHM---EGPSLIHVG 469 +L KD+ + + +SE + L I L L + H E S++ Sbjct: 1832 LITLKKDVNETQKKVSEMEQLKKQIKDQSLTLSKLEIENLNLAQELHENLEEMKSVMKER 1891 Query: 470 TNTEDVNEIAKVQ-EQLKQELND-EIKDVNVKDLIEKL----KSAEEQITQLNDEIDAAN 523 N V E K++ +QLK+ L + + +D+ ++ ++ K +E + +L ++I Sbjct: 1892 DNLRRVEETLKLERDQLKESLQETKARDLEIQQELKTARMLSKEHKETVDKLREKISEKT 1951 Query: 524 KNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQL 583 + ++ + ++QK I K +++R+ E+++ +K+ E+E+ K + Sbjct: 1952 IQISDIQKDLDKSKDELQKKIQELQK---KELQLLRVKEDVNMSHKKINEMEQLKKQFEP 2008 Query: 584 HLV---DYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKY--D 638 + + + D+ ++ + +++ + E+ +A+ R + + ES K + Q + L++ D Sbjct: 2009 NYLCKCEMDNFQLTKK-LHESLEEIRIVAKERDELRRIKESLKMERDQFIATLREMIARD 2067 Query: 639 EVEDKLADISQLQSD----------QVCSEIKSV-----HLEEQIDALSASKKELALVIE 683 ++ +L SD + CS IK + +++ + L+ +L IE Sbjct: 2068 RQNHQVKPEKRLLSDGQQHLMESLREKCSRIKELLKRYSEMDDHYECLNRLSLDLEKEIE 2127 Query: 684 NLKLDKEQLY--GTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINH 741 ++ K+ Y + ++ ++ + +NK + MD D++EK ELL KI H Sbjct: 2128 FHRIMKKLKYVLSYVTKIKEEQHECINKFE------MDFIDEVEKQK-----ELLIKIQH 2176 Query: 742 EEQS-KIQTQFGIDAKI-QERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKA 799 +Q + ++ D K+ Q DL+IE I + S+ + + E V+ +R+ + Sbjct: 2177 LQQDCDVPSRELRDLKLNQNMDLHIEEILKDFSESEFPSIKTEFQ-QVLSNRKEMTQFLE 2235 Query: 800 DQLGSYLQ-EK-----QKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEI----EHENK 849 + L + EK QK + NR+ +M+ E++ I E + K Sbjct: 2236 EWLNTRFDIEKLKNGIQKENDRICQVNNFFNNRIIAIMNESTEFEERSATISKEWEQDLK 2295 Query: 850 ELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQ-LRDLESNL- 907 L++KN+ L + Q L+ SL+ Q N + N+ S +T+ T+ +R+LE++L Sbjct: 2296 SLKEKNEKLFKNYQTLKTSLASGAQ-VNPTTQD-NKNPHVTSRATQLTTEKIRELENSLH 2353 Query: 908 --KRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQ-L 964 K ++ I++ +KE+E + + ++++ + + EK ++ I+ + A Sbjct: 2354 EAKESAMHKESKIIKMQKELE-VTNDIIAKLQAKVHESNKCLEKTKETIQVLQDKVALGA 2412 Query: 965 QEYKNNIENLNMNVE--ELNKM-NLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQK 1021 + YK IE+L M + +L KM N + +K + + + +Y ++ I + + N Q+ Sbjct: 2413 KPYKEEIEDLKMKLVKIDLEKMKNAKEFEKEISATKA-TVEYQKEVIRLLRE-NLRRSQQ 2470 Query: 1022 DEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEEL 1081 ++ +++ + Q S + S + Q TK ++ E R+ K++ KQ NE+L Sbjct: 2471 AQDTSVISEH-TDPQPSNKPLTCGGGSGIVQ-NTKALILKSEHIRLEKEISKLKQQNEQL 2528 Score = 100 bits (240), Expect = 3e-19 Identities = 199/982 (20%), Positives = 409/982 (41%), Gaps = 91/982 (9%) Query: 153 EKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXE 212 E + L V +K E TI +L+ ++EK+ I K E Sbjct: 1474 ETEEELKVAHCCLKEQEETINELRVNLSEKETEISTIQKQLEAINDKLQNKIQEIYEKEE 1533 Query: 213 DTK-QQMTKMQENFIAMEA--EWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISL 269 +Q++++QEN ++ E + K L+ IESK LE N+L E+ EI + Sbjct: 1534 QLNIKQISEVQENVNELKQFKEHRKAKDSALQSIESK-----MLELTNRLQESQE-EIQI 1587 Query: 270 EHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGS-LEIANMTELTKKI 328 + +E E+ L + + E + K E++ L++ + E +K+ Sbjct: 1588 ----MIKEKEEMKRVQEALQIERDQLKENTKEIVAKMKESQEKEYQFLKMTAVNETQEKM 1643 Query: 329 ELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSG--RNTASKMKSPW 386 +EHL Q LEN + T + + + ++++ R+ +K Sbjct: 1644 CEIEHLKEQFETQKLNLEN-IETENIRLTQILHENLEEMRSVTKERDDLRSVEETLKVER 1702 Query: 387 SQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDK-EYVISEKDTXXXXXXXXXXGK 445 QL E L + + + K E K+ + +++ +DK ++SEK Sbjct: 1703 DQLK-ENLRETITRDLEKQEELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHS 1761 Query: 446 DTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVN-----VKD 500 + + L+ Q+ + + H+ E ++++ + + +L++ KD+ +++ Sbjct: 1762 NDALKAQDLKIQEELRIAHM-HLKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQE 1820 Query: 501 LIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRL 560 I++LK+ E Q+ L +++ K KV +LK KQ++ SK+ N + L Sbjct: 1821 KIQELKANEHQLITLKKDVNETQK---KVSEMEQLK-KQIKDQSLTLSKLEIEN---LNL 1873 Query: 561 TEELHHLSQKVAELEEEKGNLQL--HLVDYDSGRMIESDVYKKMIEMENLAETRLKAISL 618 +ELH +++ + +E+ NL+ + + ++ ES K ++E + LK + Sbjct: 1874 AQELHENLEEMKSVMKERDNLRRVEETLKLERDQLKESLQETKARDLE--IQQELKTARM 1931 Query: 619 LESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKEL 678 L + + V +L +++ +K IS +Q D S+ + L+++I L KKEL Sbjct: 1932 LSKEHKETVDKLR------EKISEKTIQISDIQKDLDKSKDE---LQKKIQELQ--KKEL 1980 Query: 679 ALVIENLKLDKEQLYGTIKDLENDKEDIM-NKLQNYIQENMDLTDKLEKMSAEKISELLA 737 L+ +K D + I ++E K+ N L +N LT KL + S E+I ++A Sbjct: 1981 QLL--RVKEDVNMSHKKINEMEQLKKQFEPNYLCKCEMDNFQLTKKLHE-SLEEI-RIVA 2036 Query: 738 KINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLER 797 K +E +I+ + ERD +I + +++ + E + + +++ +E Sbjct: 2037 K-ERDELRRIKESLKM-----ERDQFIATLREMIARDRQNHQVKPEKRLLSDGQQHLMES 2090 Query: 798 KADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHD----RVVEKQLLEIEHENKELQK 853 ++ S ++E K YSE E +NRL++ ++ + R+++K + + K ++ Sbjct: 2091 LREKC-SRIKELLKRYSEMD-DHYECLNRLSLDLEKEIEFHRIMKKLKYVLSYVTKIKEE 2148 Query: 854 KNQIL----------LEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDL 903 +++ + +E+ + L I + +QQ + + L ++ + L+D Sbjct: 2149 QHECINKFEMDFIDEVEKQKELLIKIQHLQQDCDVPSRELRDLKLNQNMDLHIEEILKDF 2208 Query: 904 -ESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEA 962 ES I E Q ++ +K+ + LE NT+ + EK + I+ Sbjct: 2209 SESEFPSIKTEFQQVLSNRKEMTQFLEEWLNTRFDI---------EKLKNGIQKENDRIC 2259 Query: 963 QLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKD 1022 Q+ + NN MN + I K ++ + E+ L L Sbjct: 2260 QVNNFFNNRIIAIMNESTEFEERSATISKEWEQDLKSLKEKNEKLFKNYQTLKTSLAS-G 2318 Query: 1023 EEIIALNQKINNAQVSYMSM------VSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQ 1076 ++ Q N V+ + + + E+ L + + E ++ ++ K+L + Sbjct: 2319 AQVNPTTQDNKNPHVTSRATQLTTEKIRELENSLHEAKESAMHKESKIIKMQKELEVTND 2378 Query: 1077 HNEELQILVREQDDQIKELKET 1098 +LQ V E + +++ KET Sbjct: 2379 IIAKLQAKVHESNKCLEKTKET 2400 Score = 79.4 bits (187), Expect = 8e-13 Identities = 160/827 (19%), Positives = 346/827 (41%), Gaps = 75/827 (9%) Query: 750 QFGIDAKIQERDLYIENIESE---LSKYKSRICRLEESI--AVMEDRRYSLERKADQLGS 804 QF AK + Y+ + ++ L +Y+ I L++ + +E R ++E+ DQL Sbjct: 321 QFASTAKYMKNTPYVNEVSTDEALLKRYRKEIMDLKKQLEEVSLETRAQAMEK--DQLAQ 378 Query: 805 YLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQN 864 L+EK +Q +++ N +L+ + +Q L+ + + + +I +N N Sbjct: 379 LLEEKDLLQK---VQNEKIENLTRMLVTSSSLTLQQELKAKRKRRVTWCLGKINKMKNSN 435 Query: 865 LQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKE 924 ++ + K + L E + + D+ SN E + K Sbjct: 436 YADQF-NIPTNITTKTHKLSINLLREIDESVCSES--DVFSNTLDTLSEIEWNPATKLLN 492 Query: 925 IEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNK- 983 E++E E N+ A D VL+ YE+ ++E +L+E KN+++ + K Sbjct: 493 QENIESELNSL--RADYDNLVLD--YEQLRTEKEEMELKLKE-KNDLDEFEALERKTKKD 547 Query: 984 MNLELIDK--HVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMS 1041 ++LI + +++ Y + NE++ LL++K+++I L + I++ ++ + Sbjct: 548 QEMQLIHEISNLKNLVKHREVYNQDLENELSSKVELLREKEDQIKKLQEYIDSQKLENIK 607 Query: 1042 MVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLT 1101 M Y + + +++ + + V+ LD+K+ + L+ E +++KEL T Sbjct: 608 MDLSYSLESIEDPKQMKQTLFDAETVA---LDAKRESAFLRSENLELKEKMKELATTYKQ 664 Query: 1102 FEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEF---IQERSVLQ 1158 E +I + + + + D + + + ++ ++ + Sbjct: 665 MENDIQLYQSQ-LEAKKKMQVDLEKELQSAFNEITKLTSLIDGKVPKDLLCNLELEGKIT 723 Query: 1159 EQSAKLNTELQE---CYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLS 1215 + +LN E++E ++I L L + L +++I +L + +E D L S Sbjct: 724 DLQKELNKEVEENEALREEVILLSELKS-LPSEVERLRKEIQDKSEELHIITSEKDKLFS 782 Query: 1216 TVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHE---LRVQLSAFESKYEQLL 1272 V S + +++ G K LA +++++ T+ E + FE KY+ +L Sbjct: 783 EVVHKESRVQGLLEEIG-----KTKDDLATTQSNYKSTDQEFQNFKTLHMDFEQKYKMVL 837 Query: 1273 DSVQSSTQEETNKIVTMEQVTS----LQNKLQDKEEHLRNLQEKYADVINQIEILRSEIE 1328 + + QE N ++ S L+ +L K + L+ + + +N++E L+ ++E Sbjct: 838 EENERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQELQEKTREVQERLNEMEQLKEQLE 897 Query: 1329 DEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXX 1388 + L TE Q + + + +E LK+ Sbjct: 898 NRDSPLQTVEREKT---------LITEK---LQQTLEEVKTLTQEKDDLKQLQESLQIER 945 Query: 1389 XXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRI 1448 ++D + + Q +L+++ K H+ TI T ++ E V + L E+ Sbjct: 946 DQLKSDIHDTVN--MNIDTQEQLRNALESLKQHQETIN-TLKSKISEEVSRNL-HMEENT 1001 Query: 1449 EDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAEL 1508 + E + ++ + K A + +T+ ++++ ++IE+ KI SL ++ EL Sbjct: 1002 GETKDEFQQKMVGIDKKQDLEAKNTQTL--TADVKDNEIIEQQR-KI---FSLIQEKNEL 1055 Query: 1509 NKALEEEVAKTNEMQT--------ALENQEIEIVTLNDEITNLQNMV 1547 + LE +A+ +++T +ENQE E+ L DE+ Q +V Sbjct: 1056 QQMLESVIAEKEQLKTDLKENIEMTIENQE-ELRLLGDELKKQQEIV 1101 Score = 53.6 bits (123), Expect = 4e-05 Identities = 172/851 (20%), Positives = 345/851 (40%), Gaps = 76/851 (8%) Query: 62 ENAALVSKRIKEHRKATAELLGRPFVPGISESLANTLKQKEILMEKIKQYKELSKRSSTT 121 E +V +KEH++ +L G V + ++N K E + +K ++L + Sbjct: 1721 EELKIVHMHLKEHQETIDKLRG--IVSEKTNEISNMQKDLEHSNDALKA-QDLKIQEELR 1777 Query: 122 IVRXXXXXXXXXXXXXXXQLGDVTH-LSNTIKEKDNALSVLQVK---MKIMETTILDL-- 175 I + + T LSN K+ +N+ + LQ K +K E ++ L Sbjct: 1778 IAHMHLKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQELKANEHQLITLKK 1837 Query: 176 -----QEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQE--NFIAM 228 Q+K++E +Q+ + + E+ ++ + M+E N + Sbjct: 1838 DVNETQKKVSEMEQLKKQIKDQSLTLSKLEIENLNLAQELHENLEEMKSVMKERDNLRRV 1897 Query: 229 EAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQEL-EQXXXXXXX 287 E K E+ +L + ++ R +++ L+ AR +S EH + +L E+ Sbjct: 1898 EETLKLERDQLKESLQETKARDLEIQQE---LKTARM-LSKEHKETVDKLREKISEKTIQ 1953 Query: 288 XXXXXXXL--AKQSIEPSCEE--KTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNK 343 L +K ++ +E K E++ E NM+ KKI +E L Q + N Sbjct: 1954 ISDIQKDLDKSKDELQKKIQELQKKELQLLRVKEDVNMSH--KKINEMEQLKKQF-EPNY 2010 Query: 344 ELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSS---ETLNQDTDK 400 + ++ K S + R R +K Q + E + +D Sbjct: 2011 LCKCEMDNFQLTKKLHESLEEIRIVAKERDELRRIKESLKMERDQFIATLREMIARDRQN 2070 Query: 401 KINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHM 460 K E L Q L + L +K I E + L L+ E + H Sbjct: 2071 HQVKPEKRLLSDGQQHLMESLREKCSRIKELLKRYSEMDDHYECLNRLSLDLEKEIEFHR 2130 Query: 461 EGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEID 520 L +V ++ + K++E+ + +N +++ D +EK K +I L + D Sbjct: 2131 IMKKLKYV------LSYVTKIKEEQHECINKF--EMDFIDEVEKQKELLIKIQHLQQDCD 2182 Query: 521 AANKNM--IKVKSNHKLKLKQMQKTIDN---------FSKVSDSNKEIVRLTEELHHLSQ 569 ++ + +K+ N L ++++ K F +V + KE+ + EE + Sbjct: 2183 VPSRELRDLKLNQNMDLHIEEILKDFSESEFPSIKTEFQQVLSNRKEMTQFLEEWLNTRF 2242 Query: 570 KVAELEE--EKGNLQLHLVD-YDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDL 626 + +L+ +K N ++ V+ + + R+I + + E E + T K E L Sbjct: 2243 DIEKLKNGIQKENDRICQVNNFFNNRIIA--IMNESTEFEERSATISKE---WEQDLKSL 2297 Query: 627 VQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASK-KELALVIENL 685 ++ L + Y ++ LA S Q + + K+ H+ + L+ K +EL + Sbjct: 2298 KEKNEKLFKNYQTLKTSLA--SGAQVNPTTQDNKNPHVTSRATQLTTEKIRELENSLHEA 2355 Query: 686 KLDKEQLYGTIKDLENDKE---DIMNKLQNYIQEN---MDLTDKLEKMSAEKISELLAKI 739 K I ++ + E DI+ KLQ + E+ ++ T + ++ +K++ L AK Sbjct: 2356 KESAMHKESKIIKMQKELEVTNDIIAKLQAKVHESNKCLEKTKETIQVLQDKVA-LGAKP 2414 Query: 740 NHEEQSKIQTQFGIDAKIQ-ERDLYIENIESELSKYKSRICRLEESIAVM-EDRRYSLER 797 EE ++ + KI E+ + E E+S K+ + +E I ++ E+ R S + Sbjct: 2415 YKEEIEDLKMKL---VKIDLEKMKNAKEFEKEISATKATVEYQKEVIRLLRENLRRSQQA 2471 Query: 798 KADQLGSYLQEKQKAYSEYTIQEDELV--NRLAVLMDHDRV-VEKQLLEIEHENKELQKK 854 + + S + Q + T + N A+++ + + +EK++ +++ +N++L K+ Sbjct: 2472 QDTSVISEHTDPQPSNKPLTCGGGSGIVQNTKALILKSEHIRLEKEISKLKQQNEQLIKQ 2531 Query: 855 NQILLEENQNL 865 LL NQ+L Sbjct: 2532 KNELLSNNQHL 2542 >UniRef50_Q23D13 Cluster: Viral A-type inclusion protein repeat containing protein; n=1; Tetrahymena thermophila SB210|Rep: Viral A-type inclusion protein repeat containing protein - Tetrahymena thermophila SB210 Length = 1753 Score = 157 bits (380), Expect = 3e-36 Identities = 263/1386 (18%), Positives = 605/1386 (43%), Gaps = 139/1386 (10%) Query: 249 RISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKT 308 ++ L+ N+ L+ + I + KL QE E + KQ+ + K Sbjct: 358 KVKDLQTLNQQLKQEKQTIDDLNQKLKQENESLKKTGNQLQQEIEQIIKQNKIKEVQNKE 417 Query: 309 EIEEKGSLEIANMTELTKKIEL-----LEHLNCQIRQTNKELENKLATMGTESKAVSSPS 363 E E + I + E KK + E + Q+ T L+ K + E +S Sbjct: 418 EFEAQNK-RIKELDERYKKEKTDYQKQNESIKSQMESTISALQEKNKLLEQERDDANS-K 475 Query: 364 KKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDL-V 422 KGS + +++ ++ + QL+ E ++I+K + E +I+ LN ++ + Sbjct: 476 LKGSQIDMQQTKIKIGEELTTLKRQLTDE-------QQISKQKKENFEKIIEQLNLEIQM 528 Query: 423 DKEYVISEKDTXXXXXXXXXXGKDTLIAQLQ-LEH--QQHMEGPSLIHVGTNTEDVNEIA 479 K+ ++T K+ ++Q LE ++ E + TE N Sbjct: 529 QKDASKEFENTISKLNAQSEANKNESQVRIQSLEEVIKKIEEELKCMKESKETETKNLKQ 588 Query: 480 KVQE--QLKQELNDEIKDVN--VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKL 535 K+ E ++L D++K +DL +KL E + + + E+D +K ++ L Sbjct: 589 KITELETSNKDLGDQLKTKTNETEDLNKKLNDLETENSNMRRELDET------IKKSNSL 642 Query: 536 KLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIE 595 ++ +++ N ++ D N+ + +E+ + +++ L EE L+ L Sbjct: 643 EILIQEQSTRNSQELKDKNEIFNQSIKEIARVKAEISSLHEENKLLKEQL---------- 692 Query: 596 SDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQV 655 + +K+++E + + E + L + L ++ + ++ D +E L + D + Sbjct: 693 ATSHKELVETKQIKEEKTVLCVQLSEKLSSLQEQFDVKSEQLDSLEISLKQKQDI-IDGL 751 Query: 656 CSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQ 715 EI+ + EQ+ + SKKE ++ K + I+ L++ +D+ + L+ + Sbjct: 752 KEEIEELE-NEQLGSAENSKKEQNSQLQQFKEQTDSFQNEIQQLKSQIQDLESNLK-FKN 809 Query: 716 ENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIEN-IESELSKY 774 E + D++ K +I KIN E+ ++ Q ++E+ L ++N +E +K Sbjct: 810 EEIIKQDEIIKNKQNEI-----KINEEKAENVKHQ------LEEKVLSLQNKLEESNNKL 858 Query: 775 KSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQK--AYSEYTIQEDELVNRLAVLMD 832 K++ + I + L ++ + L L+E + AY + +++ E +++ ++ + Sbjct: 859 KTQEEESAKEIEEAQSSFLKLRQELEVLKLSLEENENNHAYEKQQMEQRE-IDKNVLIEE 917 Query: 833 HDRVVEKQ------LLEIEHENKE-LQKKNQILLEENQNLQISLSDMQQHYNALVEKANR 885 ++R V +Q L ++ +NKE +Q+K++ +LE+ + ++ + + + N L ++ + Sbjct: 918 YERKVREQNQELTSLTAMQRKNKEEIQRKDETILEKEKRIKQNQDKLSEVQNELKKQNQQ 977 Query: 886 TDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIE---DLEIEFNTQIESAIRD 942 D + ++ + + + + E L+R + I QK+++I E + QI++ +++ Sbjct: 978 LDEYKQQNQQLEERAINAEQELER----EKMQIAQKEEQISLTRKSNEEQSNQIQNFLKE 1033 Query: 943 KKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLN----MNVEELNKMNLELIDKHVQKQQT 998 + LN K + +EY+ +LE +E + I LN + EE++K +E + K + + Sbjct: 1034 IQELNNKVNEQVEYIAELEQLKEETNSQINELNQEQKLKYEEMHKQ-IEKLQKQCDFKDS 1092 Query: 999 QSPDYTEQYINEIN----KLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFT 1054 Q E+ ++ + N+ L +K+E I Q + ++ S + D E++ + Sbjct: 1093 QYQQLKEELSSQDQAKEERSNSTLTEKEERI----QNLEKSKFDLESSLQDKENECERLV 1148 Query: 1055 TKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMII 1114 ++ N +++++++ +L S Q L+ ++ ++++I +K++++T M + Sbjct: 1149 QQVNNFQQQVKKLKDDILTSTQETATLKKSIQLKENEIL-VKQSEITKLMRESQESIDSK 1207 Query: 1115 SSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLN-------TE 1167 + E ++ D +N++ LK Q + QE S L+E + + +E Sbjct: 1208 NQFKESLTRDIHNLNSNIQSKEREIIQLKSQVQT-LNQELSELKESNNQFQIIIDQAESE 1266 Query: 1168 LQECYTKII--QLETLNTELTGHDVVN--QEQINQLKSKLEQLNTEN-DNLLSTVAE--- 1219 E + + E E T D +E+I L+ KL+ L ++ + ++ ++ E Sbjct: 1267 KNEAQRTSLSNKAELDEIEQTYQDAQQKLEEKIRSLQEKLQLLEQKSKEEMMMSLKENSD 1326 Query: 1220 LRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSST 1279 L+ ++ +Q + ++ K+H +AD QK+ E + Q+S SK E+L S + T Sbjct: 1327 LKGKLNMFEEQHKLKYSDYEKKH----QAD-QKSIEEQKKQISTQLSKIEELELSQAAIT 1381 Query: 1280 QEETN---KIVTMEQVTSLQNKLQDKEEH-----LRNLQEKYADVINQIEILRSEIED-- 1329 Q+ N ++ + E+V + N + +H + L++K + ++ L++++ + Sbjct: 1382 QQLENLKAELKSKEEVINGLNNQDQQNQHSKDGQIETLKQKLLSLESEKLELQNQVNELE 1441 Query: 1330 EKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXX 1389 +++ E ++ + Q I+ +N+ ++S+ Sbjct: 1442 QQLKKIQHKNEQLTKSNEQFVSQLVEKENETESLGQKIILLNKSVTAYEQSNKKLKSEQQ 1501 Query: 1390 XXXXRVNDAEAKVLELTHQLEL--------KDSEIYQKTHEYTITLTQRNDEFENVRQQL 1441 ++ E K + + + K+ E+ K E T + Q +++ +L Sbjct: 1502 DLLDKIRVIENKSKKSSSPPKTQPINNNPSKEKELQNKIDEQTQLIKQ----YQHSLGKL 1557 Query: 1442 VEYEKRIEDLTYEKESELAILRLKMHENANH-------YETMQKESEIERVKLIEELNVK 1494 E E+RI+ E ++R N + ++ +++E+ +VK+ E++ +K Sbjct: 1558 NELEERIQLKNEENLILQQMIRQITSNNPKNEGVSAIAFDKIKQENSDLKVKM-EKIMLK 1616 Query: 1495 ----ITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRAS 1550 I ++ +V L L E+V T ++ + E++ +E L++ V + Sbjct: 1617 YKQIIVRYIAKFSKVVNLKAQLSEQVKVTESLKGKFKLLNEEVIKFEEENKVLKSCVTKN 1676 Query: 1551 SSKIQK 1556 +I++ Sbjct: 1677 KKEIEE 1682 Score = 155 bits (377), Expect = 7e-36 Identities = 238/1164 (20%), Positives = 510/1164 (43%), Gaps = 108/1164 (9%) Query: 506 KSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELH 565 KS++ D ID K+ + + S L + D + N+++ + + + Sbjct: 318 KSSDNPFELQKDMIDKTQKDDLLINSKWNLNEIPIPIYQDKVKDLQTLNQQLKQEKQTID 377 Query: 566 HLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFD 625 L+QK L++E +L+ +G ++ ++ +++I+ + E + K ++++ Sbjct: 378 DLNQK---LKQENESLK------KTGNQLQQEI-EQIIKQNKIKEVQNKEEFEAQNKRIK 427 Query: 626 LVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENL 685 + E + ++K D + + SQ++S + K+ LE++ D ++ K + ++ Sbjct: 428 ELDERY-KKEKTDYQKQNESIKSQMESTISALQEKNKLLEQERDDANSKLKGSQIDMQQT 486 Query: 686 KLDKEQLYGTIKDLENDKEDIMN-KLQNY--IQENMDLTDKLEKMSAEKISELLAKIN-- 740 K+ + T+K D++ I K +N+ I E ++L +++K ++++ ++K+N Sbjct: 487 KIKIGEELTTLKRQLTDEQQISKQKKENFEKIIEQLNLEIQMQKDASKEFENTISKLNAQ 546 Query: 741 -----HEEQSKIQTQFGIDAKIQER-DLYIENIESELSKYKSRICRLEESIAVMEDRRYS 794 +E Q +IQ+ + KI+E E+ E+E K +I LE S + D+ + Sbjct: 547 SEANKNESQVRIQSLEEVIKKIEEELKCMKESKETETKNLKQKITELETSNKDLGDQLKT 606 Query: 795 LERKADQLGSYLQEKQKAYSEYTIQEDELV---NRLAVLMDHDRVVEKQLLEIEHE--NK 849 + + L L + + S + DE + N L +L+ Q L+ ++E N+ Sbjct: 607 KTNETEDLNKKLNDLETENSNMRRELDETIKKSNSLEILIQEQSTRNSQELKDKNEIFNQ 666 Query: 850 ELQK----KNQI--LLEENQNLQISLSDMQQHYNALVE-KANRTDLAESESTKYQT---- 898 +++ K +I L EEN+ L+ L+ + + K +T L S K + Sbjct: 667 SIKEIARVKAEISSLHEENKLLKEQLATSHKELVETKQIKEEKTVLCVQLSEKLSSLQEQ 726 Query: 899 ------QLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEK 952 QL LE +LK + Q +I K+EIE+LE N Q+ SA KK N + ++ Sbjct: 727 FDVKSEQLDSLEISLK----QKQDIIDGLKEEIEELE---NEQLGSAENSKKEQNSQLQQ 779 Query: 953 NIEYVTQLEAQLQEYKNNIENLNMNV----EEL--------NKMN-LELIDKHVQKQQTQ 999 E + ++Q+ K+ I++L N+ EE+ NK N +++ ++ + + Q Sbjct: 780 FKEQTDSFQNEIQQLKSQIQDLESNLKFKNEEIIKQDEIIKNKQNEIKINEEKAENVKHQ 839 Query: 1000 SPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLEN 1059 + N++ + N LK ++EE ++I AQ S++ + + E N Sbjct: 840 LEEKVLSLQNKLEESNNKLKTQEEESA---KEIEEAQSSFLKLRQELEVLKLSLEENENN 896 Query: 1060 MEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIE 1119 E Q++ ++ +D EE + VREQ+ ++ T LT K E I E Sbjct: 897 HAYEKQQMEQREIDKNVLIEEYERKVREQNQEL-----TSLTAMQRKNKEE---IQRKDE 948 Query: 1120 PMSDDANNVDXXXXXXXXXXXXLKVQEEE--EFIQERSVLQEQSAKLNTELQECYTKIIQ 1177 + + + LK Q ++ E+ Q+ L+E++ EL+ +I Q Sbjct: 949 TILEKEKRIKQNQDKLSEVQNELKKQNQQLDEYKQQNQQLEERAINAEQELEREKMQIAQ 1008 Query: 1178 LETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAE 1237 E LT N+EQ NQ+++ L+++ E +N ++ E + + ++ +I E Sbjct: 1009 KEE-QISLTRKS--NEEQSNQIQNFLKEIQ-ELNNKVNEQVEYIAELEQLKEETNSQINE 1064 Query: 1238 LWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQ---EETNKIVTM--EQV 1292 L ++ + E + K +L+ Q +S+Y+QL + + S Q E +N +T E++ Sbjct: 1065 LNQEQKLKYE-EMHKQIEKLQKQCDFKDSQYQQLKEELSSQDQAKEERSNSTLTEKEERI 1123 Query: 1293 TSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDL 1352 +L+ D E L++ + + ++ Q+ + +++ K+ L Sbjct: 1124 QNLEKSKFDLESSLQDKENECERLVQQVNNFQQQVK--KLKDDILTSTQETATLKKSIQL 1181 Query: 1353 RTENQSYKQMQEQSILNINEENAQLKKS-SXXXXXXXXXXXXRVNDAEAKVLELTHQLEL 1411 + KQ + ++ ++E+ K + E ++++L Q++ Sbjct: 1182 KENEILVKQSEITKLMRESQESIDSKNQFKESLTRDIHNLNSNIQSKEREIIQLKSQVQT 1241 Query: 1412 KD---SEIYQKTHEYTITLTQRNDEFENVRQ-------QLVEYEKRIEDLTYEKESELAI 1461 + SE+ + +++ I + Q E ++ +L E E+ +D + E ++ Sbjct: 1242 LNQELSELKESNNQFQIIIDQAESEKNEAQRTSLSNKAELDEIEQTYQDAQQKLEEKIRS 1301 Query: 1462 L--RLKMHENANHYETM---QKESEIE-RVKLIEELNVKITESVSLNKQVAELNKALEEE 1515 L +L++ E + E M ++ S+++ ++ + EE + K+ S K A+ K++EE+ Sbjct: 1302 LQEKLQLLEQKSKEEMMMSLKENSDLKGKLNMFEEQH-KLKYSDYEKKHQAD-QKSIEEQ 1359 Query: 1516 VAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNT 1575 + + + +E E+ + ++ NL+ +++ I + + +D Q++ Sbjct: 1360 KKQISTQLSKIEELELSQAAITQQLENLKAELKSKEEVINGLNNQDQQNQHSKDGQIETL 1419 Query: 1576 MNKELLDAVPRAELDLAMYMLHQR 1599 K L + EL + L Q+ Sbjct: 1420 KQKLLSLESEKLELQNQVNELEQQ 1443 Score = 145 bits (352), Expect = 8e-33 Identities = 217/1007 (21%), Positives = 443/1007 (43%), Gaps = 85/1007 (8%) Query: 144 VTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINE--KDQIIEAKN--KATTXXXXX 199 ++ L K L L++ +K + I L+E+I E +Q+ A+N K Sbjct: 720 LSSLQEQFDVKSEQLDSLEISLKQKQDIIDGLKEEIEELENEQLGSAENSKKEQNSQLQQ 779 Query: 200 XXXXXXXXXXXXEDTKQQMTKMQENF------IAMEAEWKDEKQRLLKDIESKDVRIS-S 252 + K Q+ ++ N I + E KQ +K E K + Sbjct: 780 FKEQTDSFQNEIQQLKSQIQDLESNLKFKNEEIIKQDEIIKNKQNEIKINEEKAENVKHQ 839 Query: 253 LEEA-----NKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEK 307 LEE NKL E + ++ + + A+E+E+ L K S+E + E Sbjct: 840 LEEKVLSLQNKL-EESNNKLKTQEEESAKEIEEAQSSFLKLRQELEVL-KLSLEEN--EN 895 Query: 308 TEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGS 367 EK +E E+ K + L+E ++R+ N+EL + A + + K + Sbjct: 896 NHAYEKQQME---QREIDKNV-LIEEYERKVREQNQELTSLTAMQRKNKEEIQR--KDET 949 Query: 368 PLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYV 427 L K + K+ ++L + NQ D+ +N+ +LE + ++L ++ Sbjct: 950 ILEKEKRIKQNQDKLSEVQNELKKQ--NQQLDEYKQQNQ--QLEERAINAEQELEREKMQ 1005 Query: 428 ISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQ 487 I++K+ + I E Q+ ++ N E V IA++ EQLK+ Sbjct: 1006 IAQKEEQISLTRKSNEEQSNQIQNFLKEIQE-------LNNKVN-EQVEYIAEL-EQLKE 1056 Query: 488 ELNDEIKDVNVKDL---------IEKLKSA----EEQITQLNDEIDAANKNMIKVKSNHK 534 E N +I ++N + IEKL+ + Q QL +E+ + ++ + +SN Sbjct: 1057 ETNSQINELNQEQKLKYEEMHKQIEKLQKQCDFKDSQYQQLKEELSSQDQAK-EERSNST 1115 Query: 535 L-----KLKQMQKT-IDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEE-KGNLQLHLVD 587 L +++ ++K+ D S + D E RL +++++ Q+V +L+++ + Q Sbjct: 1116 LTEKEERIQNLEKSKFDLESSLQDKENECERLVQQVNNFQQQVKKLKDDILTSTQETATL 1175 Query: 588 YDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADI 647 S ++ E+++ K E+ L ++I K L +++H L E ++ + Sbjct: 1176 KKSIQLKENEILVKQSEITKLMRESQESIDSKNQFKESLTRDIHNLNSNIQSKEREIIQL 1235 Query: 648 -SQLQS-DQVCSEIKSVHLEEQI--DALSASKKELALVIENLKLDKEQLYGTIKDLENDK 703 SQ+Q+ +Q SE+K + + QI D + K E + K + +++ T +D + Sbjct: 1236 KSQVQTLNQELSELKESNNQFQIIIDQAESEKNEAQRTSLSNKAELDEIEQTYQDAQQKL 1295 Query: 704 EDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKIN-HEEQSKIQTQFGIDAKIQERDL 762 E+ + LQ +Q + + MS ++ S+L K+N EEQ K++ + K Q Sbjct: 1296 EEKIRSLQEKLQLLEQKSKEEMMMSLKENSDLKGKLNMFEEQHKLKYS-DYEKKHQADQK 1354 Query: 763 YIENIESELSKYKSRICRLEESIAV----MEDRRYSLERKADQLGSYLQEKQKAYSEYTI 818 IE + ++S S+I LE S A +E+ + L+ K + + + Q+ Sbjct: 1355 SIEEQKKQISTQLSKIEELELSQAAITQQLENLKAELKSKEEVINGLNNQDQQNQHSKDG 1414 Query: 819 QEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNA 878 Q + L +L L ++ Q+ E+E + K++Q KN+ L + N +Q + Sbjct: 1415 QIETLKQKLLSLESEKLELQNQVNELEQQLKKIQHKNEQLTKSN----------EQFVSQ 1464 Query: 879 LVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIES 938 LVEK N T+ + + E + K++ E Q L+ K + IE+ + ++ ++ Sbjct: 1465 LVEKENETESLGQKIILLNKSVTAYEQSNKKLKSEQQDLL-DKIRVIENKSKKSSSPPKT 1523 Query: 939 -AIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLEL--IDKHVQK 995 I + ++ + I+ TQL Q Q + L ++ N+ NL L + + + Sbjct: 1524 QPINNNPSKEKELQNKIDEQTQLIKQYQHSLGKLNELEERIQLKNEENLILQQMIRQITS 1583 Query: 996 QQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTT 1055 ++ + ++I + N+ LK K E+I+ ++I ++ S V + +++L++ Sbjct: 1584 NNPKNEGVSAIAFDKIKQENSDLKVKMEKIMLKYKQIIVRYIAKFSKVVNLKAQLSEQVK 1643 Query: 1056 KLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTF 1102 E+++ + + ++++++ ++ N+ L+ V + +I+E K+ +L + Sbjct: 1644 VTESLKGKFKLLNEEVIKFEEENKVLKSCVTKNKKEIEE-KDQQLEY 1689 Score = 134 bits (323), Expect = 3e-29 Identities = 190/979 (19%), Positives = 407/979 (41%), Gaps = 72/979 (7%) Query: 632 ILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQ 691 I KY ++ +A + D +CS+ E Q D + ++K+ L+ L++ Sbjct: 292 ISTSKYTQLIKYIATFLFINRDSICSKSSDNPFELQKDMIDKTQKDDLLINSKWNLNEIP 351 Query: 692 L---YGTIKDLENDKEDIMNKLQNYIQENMDL---TDKLEKMSAEKISELLAKINHEEQS 745 + +KDL+ + + + Q N L + L+K + E+ I + Sbjct: 352 IPIYQDKVKDLQTLNQQLKQEKQTIDDLNQKLKQENESLKKTGNQLQQEIEQIIKQNKIK 411 Query: 746 KIQTQFGIDA---KIQERDLYIENIESELSKYKSRI-CRLEESIAVMEDRRYSLERKADQ 801 ++Q + +A +I+E D + +++ K I ++E +I+ ++++ LE++ D Sbjct: 412 EVQNKEEFEAQNKRIKELDERYKKEKTDYQKQNESIKSQMESTISALQEKNKLLEQERDD 471 Query: 802 LGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEE 861 S L+ Q + I+ E + L + ++ + KQ +K+N + E Sbjct: 472 ANSKLKGSQIDMQQTKIKIGEELTTLKRQLTDEQQISKQ-----------KKENFEKIIE 520 Query: 862 NQNLQISL-SDMQQHYNALVEKANRTDLAESESTKYQTQLR--DLESNLKRITHEHQTLI 918 NL+I + D + + + K N A+SE+ K ++Q+R LE +K+I E + + Sbjct: 521 QLNLEIQMQKDASKEFENTISKLN----AQSEANKNESQVRIQSLEEVIKKIEEELKCMK 576 Query: 919 VQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNV 978 K+ E ++L+ + T++E++ +D L ++ + L +L + + N+ + Sbjct: 577 ESKETETKNLKQKI-TELETSNKD---LGDQLKTKTNETEDLNKKLNDLETENSNMRREL 632 Query: 979 EE-LNKMN-LE-LIDKHVQKQQTQSPDYTE---QYINEINKLNALLKQKDEEIIALNQKI 1032 +E + K N LE LI + + + D E Q I EI ++ A + EE L +++ Sbjct: 633 DETIKKSNSLEILIQEQSTRNSQELKDKNEIFNQSIKEIARVKAEISSLHEENKLLKEQL 692 Query: 1033 NNAQVSYMSMVSDYESK---LAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQD 1089 + + E K Q + KL +++E+ S+QL + ++ Q ++ Sbjct: 693 ATSHKELVETKQIKEEKTVLCVQLSEKLSSLQEQFDVKSEQLDSLEISLKQKQDIIDGLK 752 Query: 1090 DQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEE 1149 ++I+EL+ +L N K + + E N + LK + EE Sbjct: 753 EEIEELENEQLGSAENSKKEQNSQLQQFKEQTDSFQNEIQQLKSQIQDLESNLKFKNEEI 812 Query: 1150 FIQERSVLQEQS-AKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNT 1208 Q+ + +Q+ K+N E E ++ + L+ + +E N+LK++ E+ Sbjct: 813 IKQDEIIKNKQNEIKINEEKAENVKHQLEEKVLSLQNK-----LEESNNKLKTQEEESAK 867 Query: 1209 ENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKY 1268 E + S+ +LR + + + E H A + ++ E + V + +E K Sbjct: 868 EIEEAQSSFLKLRQEL----EVLKLSLEENENNH-AYEKQQMEQREIDKNVLIEEYERKV 922 Query: 1269 -EQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEI 1327 EQ + + + NK E++ + +KE+ ++ Q+K ++V N+++ ++ Sbjct: 923 REQNQELTSLTAMQRKNK----EEIQRKDETILEKEKRIKQNQDKLSEVQNELKKQNQQL 978 Query: 1328 EDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXX 1387 ++ K +L E Q +EQ L + N + Sbjct: 979 DEYK----QQNQQLEERAINAEQELEREKMQIAQKEEQISLT-RKSNEEQSNQIQNFLKE 1033 Query: 1388 XXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQL----VE 1443 +VN+ + EL E +S+I + E + + + + E +++Q + Sbjct: 1034 IQELNNKVNEQVEYIAELEQLKEETNSQINELNQEQKLKYEEMHKQIEKLQKQCDFKDSQ 1093 Query: 1444 YEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELN--VKITESV-S 1500 Y++ E+L+ + +++ + E + ++K L ++ N ++ + V + Sbjct: 1094 YQQLKEELSSQDQAKEERSNSTLTEKEERIQNLEKSKFDLESSLQDKENECERLVQQVNN 1153 Query: 1501 LNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSF 1560 +QV +L + +T ++ +++ +E EI+ EIT L +R S I F Sbjct: 1154 FQQQVKKLKDDILTSTQETATLKKSIQLKENEILVKQSEITKL---MRESQESIDSKNQF 1210 Query: 1561 ASDTKQGRDEQLDNTMNKE 1579 + N +KE Sbjct: 1211 KESLTRDIHNLNSNIQSKE 1229 Score = 134 bits (323), Expect = 3e-29 Identities = 233/1204 (19%), Positives = 517/1204 (42%), Gaps = 120/1204 (9%) Query: 152 KEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXX 211 + K+ L+ K+ +ET+ DL +++ K E NK Sbjct: 577 ESKETETKNLKQKITELETSNKDLGDQLKTKTNETEDLNKKLNDLETENSNMRRELDETI 636 Query: 212 EDTKQQMTKMQENFIAMEAEWKDEKQ---RLLKDIESKDVRISSLEEANKLLEAARFEIS 268 + + +QE E KD+ + + +K+I ISSL E NKLL+ +++ Sbjct: 637 KKSNSLEILIQEQSTRNSQELKDKNEIFNQSIKEIARVKAEISSLHEENKLLKE---QLA 693 Query: 269 LEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKI 328 H +L + + L+ S++ + K+ E+ SLEI+ L +K Sbjct: 694 TSHKELVETKQIKEEKTVLCVQLSEKLS--SLQEQFDVKS--EQLDSLEIS----LKQKQ 745 Query: 329 ELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQ 388 ++++ L +I +ELEN+ SK + S+ S +N ++KS Sbjct: 746 DIIDGLKEEI----EELENEQLGSAENSKKEQN-SQLQQFKEQTDSFQNEIQQLKSQIQD 800 Query: 389 LSS-------ETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXX 441 L S E + QD K +NEI E +++ L +K V+S ++ Sbjct: 801 LESNLKFKNEEIIKQDEIIKNKQNEIKINEEKAENVKHQLEEK--VLSLQNKLEESNNKL 858 Query: 442 XXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDL 501 ++ +++ ++ + V + + NE E+ + E + K+V +++ Sbjct: 859 KTQEEESAKEIEEAQSSFLKLRQELEVLKLSLEENENNHAYEKQQMEQREIDKNVLIEEY 918 Query: 502 IEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLT 561 K++ +++T L KN +++ + L++ ++ N K+S+ E+ + Sbjct: 919 ERKVREQNQELTSLT---AMQRKNKEEIQRKDETILEKEKRIKQNQDKLSEVQNELKKQN 975 Query: 562 EELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLES 621 ++L Q+ +LEE N + L E + + + E ++ TR K+ + Sbjct: 976 QQLDEYKQQNQQLEERAINAEQEL---------EREKMQIAQKEEQISLTR-KSNEEQSN 1025 Query: 622 QKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALV 681 Q + ++E+ L K +E + +A++ QL+ ++ S+I ++ E+ Sbjct: 1026 QIQNFLKEIQELNNKVNEQVEYIAELEQLK-EETNSQINELNQEQ--------------- 1069 Query: 682 IENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKL-EKMSAEKISELLAKIN 740 KL E+++ I+ L+ + D + ++E + D+ E+ S ++E +I Sbjct: 1070 ----KLKYEEMHKQIEKLQK-QCDFKDSQYQQLKEELSSQDQAKEERSNSTLTEKEERIQ 1124 Query: 741 HEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLER--- 797 + E+SK F +++ +Q+++ E + +++ ++ ++ +L++ I +L++ Sbjct: 1125 NLEKSK----FDLESSLQDKENECERLVQQVNNFQQQVKKLKDDILTSTQETATLKKSIQ 1180 Query: 798 --------KADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENK 849 K ++ ++E Q++ ++ L + L + + E+++++++ + + Sbjct: 1181 LKENEILVKQSEITKLMRESQESIDSKNQFKESLTRDIHNLNSNIQSKEREIIQLKSQVQ 1240 Query: 850 ELQKKNQILLEENQNLQISLSDMQQHYNAL--VEKANRTDLAESESTKYQTQLRDLESNL 907 L ++ L E N QI + + N +N+ +L E E T YQ + LE + Sbjct: 1241 TLNQELSELKESNNQFQIIIDQAESEKNEAQRTSLSNKAELDEIEQT-YQDAQQKLEEKI 1299 Query: 908 KRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQ-LQE 966 + + + Q L+ QK KE + ++ N+ ++ + + ++ + E Q + + ++E Sbjct: 1300 RSLQEKLQ-LLEQKSKEEMMMSLKENSDLKGKLNMFEEQHKLKYSDYEKKHQADQKSIEE 1358 Query: 967 YKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLK-QKDEEI 1025 K I +EEL +++ I + ++ + + E+ IN +N + + KD +I Sbjct: 1359 QKKQISTQLSKIEEL-ELSQAAITQQLENLKAELKS-KEEVINGLNNQDQQNQHSKDGQI 1416 Query: 1026 IALNQK---INNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEEL- 1081 L QK + + ++ + V++ E +L + K E + + ++ QL++ + E L Sbjct: 1417 ETLKQKLLSLESEKLELQNQVNELEQQLKKIQHKNEQLTKSNEQFVSQLVEKENETESLG 1476 Query: 1082 -QILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXX 1140 +I++ + E KL E + +I + + S Sbjct: 1477 QKIILLNKSVTAYEQSNKKLKSEQQDLLDKIRVIENKSKKSSSPPKTQPINNNPSKEKEL 1536 Query: 1141 XLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLK 1200 K+ E+ + I++ Q KLN EL+E +++ N E +++ Q+ I Q+ Sbjct: 1537 QNKIDEQTQLIKQ---YQHSLGKLN-ELEE------RIQLKNEE----NLILQQMIRQIT 1582 Query: 1201 SKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQ 1260 S N +N+ + + + +S + + +I +KQ + + A F K + L+ Q Sbjct: 1583 SN----NPKNEGVSAIAFDKIKQENSDLKVKMEKIMLKYKQIIVRYIAKFSKVVN-LKAQ 1637 Query: 1261 LS-------AFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKY 1313 LS + + K++ L + V EE NK++ VT + ++++K++ L L +++ Sbjct: 1638 LSEQVKVTESLKGKFKLLNEEVIKF--EEENKVL-KSCVTKNKKEIEEKDQQLEYLSQRH 1694 Query: 1314 ADVI 1317 I Sbjct: 1695 QQQI 1698 Score = 92.7 bits (220), Expect = 8e-17 Identities = 196/1021 (19%), Positives = 419/1021 (41%), Gaps = 101/1021 (9%) Query: 50 RQIKFERAQKCLENAALVSKRIKEHRKATAELLGRPFVPGISESLANTLKQKEILMEKIK 109 +QIK E+ C++ + +S ++E +E L +SL +LKQK+ +++ +K Sbjct: 703 KQIKEEKTVLCVQLSEKLSS-LQEQFDVKSEQL---------DSLEISLKQKQDIIDGLK 752 Query: 110 QYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNALSVLQVKMKIME 169 + E + Q N I++ + + L+ +K Sbjct: 753 EEIEELENEQLGSAENSKKEQNSQLQQFKEQTDS---FQNEIQQLKSQIQDLESNLKFKN 809 Query: 170 TTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAME 229 I+ E I K I+ + E++ ++ K QE A E Sbjct: 810 EEIIKQDEIIKNKQNEIKINEEKAENVKHQLEEKVLSLQNKLEESNNKL-KTQEEESAKE 868 Query: 230 AEWKDEKQRLLKDIESKDVRISSLEEA--NKLLEAARFEI-SLEHSKLAQELEQXXXXXX 286 E + + LK + +V SLEE N E + E ++ + L +E E+ Sbjct: 869 IE--EAQSSFLKLRQELEVLKLSLEENENNHAYEKQQMEQREIDKNVLIEEYERKVREQN 926 Query: 287 XXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQI---RQTNK 343 + +++ E + I EK N +L++ L+ N Q+ +Q N+ Sbjct: 927 QELTSLTAMQRKNKEEIQRKDETILEKEKRIKQNQDKLSEVQNELKKQNQQLDEYKQQNQ 986 Query: 344 ELENKL--ATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKK 401 +LE + A E + + K+ ++RKS ++++++ ++ + LN +++ Sbjct: 987 QLEERAINAEQELEREKMQIAQKEEQISLTRKSNEEQSNQIQNFLKEI--QELNNKVNEQ 1044 Query: 402 INKNEIAKLEMVIQSLNKDL----VDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLE-- 455 + IA+LE + + N + +++ E KD+ QL+ E Sbjct: 1045 VEY--IAELEQLKEETNSQINELNQEQKLKYEEMHKQIEKLQKQCDFKDSQYQQLKEELS 1102 Query: 456 -HQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQ 514 Q E S + E + + K + L+ L D K+ + L++++ + ++Q+ + Sbjct: 1103 SQDQAKEERSNSTLTEKEERIQNLEKSKFDLESSLQD--KENECERLVQQVNNFQQQVKK 1160 Query: 515 LNDEI------DAANKNMIKVKSNHKLK--------LKQMQKTIDNFSKVSDS------- 553 L D+I A K I++K N L +++ Q++ID+ ++ +S Sbjct: 1161 LKDDILTSTQETATLKKSIQLKENEILVKQSEITKLMRESQESIDSKNQFKESLTRDIHN 1220 Query: 554 --------NKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRM-IESDVYKKMIE 604 +EI++L ++ L+Q+++EL+E Q+ + +S + + E Sbjct: 1221 LNSNIQSKEREIIQLKSQVQTLNQELSELKESNNQFQIIIDQAESEKNEAQRTSLSNKAE 1280 Query: 605 MENLAETRLKAISLLESQKFDLVQELHILQQKY-DEVEDKLADISQLQS------DQVCS 657 ++ + +T A LE + L ++L +L+QK +E+ L + S L+ +Q Sbjct: 1281 LDEIEQTYQDAQQKLEEKIRSLQEKLQLLEQKSKEEMMMSLKENSDLKGKLNMFEEQHKL 1340 Query: 658 EIKSVHLEEQID--ALSASKKELALV---IENLKLDKEQLYGTIKDLEND---KEDIMNK 709 + + Q D ++ KK+++ IE L+L + + +++L+ + KE+++N Sbjct: 1341 KYSDYEKKHQADQKSIEEQKKQISTQLSKIEELELSQAAITQQLENLKAELKSKEEVING 1400 Query: 710 LQNYIQENMDLTD--------KLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERD 761 L N Q+N D KL + +EK+ EL ++N EQ + Q + + + Sbjct: 1401 LNNQDQQNQHSKDGQIETLKQKLLSLESEKL-ELQNQVNELEQQLKKIQHKNEQLTKSNE 1459 Query: 762 LYIENI---ESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQ--EKQKAYSEY 816 ++ + E+E +I L +S+ E L+ + L ++ E + S Sbjct: 1460 QFVSQLVEKENETESLGQKIILLNKSVTAYEQSNKKLKSEQQDLLDKIRVIENKSKKSSS 1519 Query: 817 TIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHY 876 + + N + + +++Q I+ L K N+ LEE L+ + + Q Sbjct: 1520 PPKTQPINNNPSKEKELQNKIDEQTQLIKQYQHSLGKLNE--LEERIQLKNEENLILQQM 1577 Query: 877 NALVEKANRTDLAESEST--KYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNT 934 + N + S K + + DL+ +++I +++ +IV+ + + + Sbjct: 1578 IRQITSNNPKNEGVSAIAFDKIKQENSDLKVKMEKIMLKYKQIIVRYIAKFSKV-VNLKA 1636 Query: 935 QIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQ 994 Q+ ++ + L K++ E V + E + + K+ + +EE ++ L +H Q Sbjct: 1637 QLSEQVKVTESLKGKFKLLNEEVIKFEEENKVLKSCVTKNKKEIEEKDQQLEYLSQRHQQ 1696 Query: 995 K 995 + Sbjct: 1697 Q 1697 Score = 49.6 bits (113), Expect = 7e-04 Identities = 84/434 (19%), Positives = 186/434 (42%), Gaps = 29/434 (6%) Query: 168 METTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIA 227 +E T D Q+K+ EK + ++ K + D K ++ +E Sbjct: 1284 IEQTYQDAQQKLEEKIRSLQEKLQLLEQKSKEEMMMSLKENS---DLKGKLNMFEEQHKL 1340 Query: 228 MEAEWKDEKQRLLKDIESKDVRISS-LEEANKL-LEAARFEISLEHSKLAQELEQXXXXX 285 ++++ + Q K IE + +IS+ L + +L L A LE+ K + ++ Sbjct: 1341 KYSDYEKKHQADQKSIEEQKKQISTQLSKIEELELSQAAITQQLENLKAELKSKEEVING 1400 Query: 286 XXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIAN-MTELTKKIELLEHLNCQIRQTNKE 344 +K + ++K E LE+ N + EL ++++ ++H N Q+ ++N++ Sbjct: 1401 LNNQDQQNQHSKDGQIETLKQKLLSLESEKLELQNQVNELEQQLKKIQHKNEQLTKSNEQ 1460 Query: 345 LENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINK 404 ++L E++++ + ++ N K+KS L + + +K Sbjct: 1461 FVSQLVEKENETESLGQKIILLNKSVTAYEQSN--KKLKSEQQDLLDK-IRVIENKSKKS 1517 Query: 405 NEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGK-DTLIAQLQLEHQQHMEGP 463 + K + + + +K+ + + ++ T GK + L ++QL++++++ Sbjct: 1518 SSPPKTQPINNNPSKEKELQNKI--DEQTQLIKQYQHSLGKLNELEERIQLKNEENLILQ 1575 Query: 464 SLIHVGTNTEDVNE--IAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEID- 520 +I T+ NE A +++KQE N ++K K +++ + I + + ++ Sbjct: 1576 QMIRQITSNNPKNEGVSAIAFDKIKQE-NSDLKVKMEKIMLKYKQIIVRYIAKFSKVVNL 1634 Query: 521 -AANKNMIKVKSNHKLKLKQMQKTIDNFSK--------VSDSNKEIVRLTEELHHLSQK- 570 A +KV + K K K + + + F + V+ + KEI ++L +LSQ+ Sbjct: 1635 KAQLSEQVKVTESLKGKFKLLNEEVIKFEEENKVLKSCVTKNKKEIEEKDQQLEYLSQRH 1694 Query: 571 ---VAELEEEKGNL 581 + L EE G+L Sbjct: 1695 QQQIILLTEENGDL 1708 >UniRef50_UPI000065DFDD Cluster: Homolog of Homo sapiens "Centromeric protein E; n=1; Takifugu rubripes|Rep: Homolog of Homo sapiens "Centromeric protein E - Takifugu rubripes Length = 2139 Score = 155 bits (377), Expect = 7e-36 Identities = 269/1344 (20%), Positives = 552/1344 (41%), Gaps = 105/1344 (7%) Query: 297 KQSIEPSCEEKTEIEEK--GSLEIAN------MTELTKKIELLEHLNCQIRQTNKELENK 348 KQ ++ E++ E+ E+ SL+ AN EL + EL+ + C + +EL + Sbjct: 787 KQQLKAELEDRMELIEQLQTSLQAANDQRIQLEDELQRNSELIIEIQCHFGRLEEELLEQ 846 Query: 349 LATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIA 408 M K +K S L +++ + +++S S+ + L +D+ E Sbjct: 847 KQKMADNMKLWE---QKESDLEQQRT--SLTEQLESAQSERDALMLEKDSRTHTYTEEKE 901 Query: 409 KLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHV 468 +L + +L+KD + + ++ + ++ QLQ QH+E Sbjct: 902 ELHRNLVTLSKDREELQEMVEMLRQEKQQLRTELEDRMEMLQQLQ----QHLE------- 950 Query: 469 GTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIK 528 ++ E+VN QLK +L + ++ + L E+L + + + L E DA+ N ++ Sbjct: 951 -SSKEEVN-------QLKSDLEENVELIQC--LKEELLNIKAERDALWSEKDASCSNSLQ 1000 Query: 529 VKSNHKLKLKQMQKTIDNFSK---VSDSNKE-----IVRLTEELHHLSQKVAELEEEKGN 580 KS+ + +L + + + +KE ++ LTEE L + L +EK Sbjct: 1001 EKSDLQSRLTSLTEEKEELQSRLVALGEDKEALQNSLISLTEEKEELQSHLTSLSKEKEE 1060 Query: 581 LQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEV 640 LQ L+ + DV ++ + E + L K L + L ++ +E+ Sbjct: 1061 LQSRLMALGE---YKEDVKSSLMSLTEEKEALQSRLMALGEDKEALQSSVQSLSKEKEEL 1117 Query: 641 EDKLADISQLQSDQVCSEIKSVH-----LEEQIDALSASKKELALVIENLKLDKEQLYGT 695 + +L + + ++D V S + S+ L+ ++ AL K+ L +++L +KE+L Sbjct: 1118 QSRLMALGEDKAD-VKSSLMSLTEEKEALQSRLMALGEDKEALQSSVQSLSKEKEELQSR 1176 Query: 696 IKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDA 755 + L DKED+ + + +E +L L + E + L + E+++ + Sbjct: 1177 LMALGEDKEDVKSSFMSLTEEKEELQSHLTALKKEDLQSSLMSLTEEKEALQSHLMALGE 1236 Query: 756 KIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYL----QEKQK 811 + + ++++ E + +SR+ L E A ++ SL + ++L S+L +EK+ Sbjct: 1237 EKEALQSSVQSLSKEKEELQSRLMALGEDKADVKSSFMSLTEEKEELQSHLTSLSKEKED 1296 Query: 812 AYSEYTI---QEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQIS 868 +S +++EL +RL L + +++ LL + E +ELQ L +E + L+ Sbjct: 1297 LHSHLASLVEEKEELQSRLVSLGEEKEDLQRSLLSLTEEKEELQSHLTSLSKEKEELKSR 1356 Query: 869 LSDMQQH----YNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKE 924 L + + N+L+ + + +S T + + + L+ + E Q L + ++ Sbjct: 1357 LESLCEEKEALQNSLMSLSGEKEELQSNLTSLSEEREEFQKILEMLRQEKQHLQAEMQER 1416 Query: 925 IEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKM 984 ++ L+ E +T + + D K + E +Q QE ++ + +L EE++++ Sbjct: 1417 VDSLQTEIST-VNKKMDDIKTERDGLMSEKEASCWASSQEQELQSRLTSLREEKEEMSEL 1475 Query: 985 NLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVS 1044 LE++ + Q+ +T+ E+ L L Q E N+++ N S Sbjct: 1476 -LEMVKREEQQLRTEMKCKLVALQTEVRTLTEKL-QGISETSQENEEMQNRLASLGIEKE 1533 Query: 1045 DYESKLAQFTTKLENMEEEMQRVSKQLLDS-KQHNEELQILVR-----EQDDQIKELKET 1098 + + Q T E E+Q++ + S ++L L++ + D K+++E Sbjct: 1534 ELQISALQQETDGGEREAELQQLLVEANSSIAALQDQLDRLIKNPIMSQLQDSNKQIQEF 1593 Query: 1099 KLTFEMNIPKTEGMIISSTIEPMSDDANN-----VDXXXXXXXXXXXXLKVQEEEEFIQE 1153 TF+ I M + T++ + NN V L++Q + + Sbjct: 1594 LGTFQQFIEACSRMKV--TVQNEAQRVNNPCPKFVPKSSRKSYSTVCQLRIQTLQCLLNT 1651 Query: 1154 RSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNL 1213 LQEQ A++ L E K +L T + ++ ++Q + E N Sbjct: 1652 MEYLQEQ-AQVYRNLFEDLLKKDRL-TFEEKCLQDVLLCRDQTYSFSVRDEDFNKLWRYR 1709 Query: 1214 LSTVAELRSSISSAVDQRGFEIAELW-KQHLAQREADFQKTEHE-LRVQLSAFESKYEQL 1271 L+ + + R+ + Q +E +LW E + EHE + QL A + +Q+ Sbjct: 1710 LTELLDKRNVYMKKM-QTIWE--KLWANMSYFTNELSAEVREHESFKEQLQA-KVGLDQI 1765 Query: 1272 L--DSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIED 1329 L + + ST ET I + L+ + + E L+ LQ + + + R + Sbjct: 1766 LGGELQRRSTMVETRNI----HLQQLREENSNMCEELKCLQVQNDSELREERSRRCSMLQ 1821 Query: 1330 EKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXX 1389 E+V D + KQ E+ L ++ + K+++ Sbjct: 1822 EEVQGAAFDTQQLLLKLQQAEDKVRLMNAEKQQLEKDQLQVHGRLSSHKEATQLLQTELQ 1881 Query: 1390 XXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITL-TQRNDEFENVRQQLVEYEK-- 1446 +V D + + L +Q LK++++Y+ T + T +V + K Sbjct: 1882 DSRAQVQDQDNTIQTLRNQ--LKEAQVYRSVLIITAAVGTFEGFCLTDVSSAEKCFAKIQ 1939 Query: 1447 RIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVA 1506 + + L KE + L+ + ++ H E + E +L + I S++ K A Sbjct: 1940 KFKVLLNTKEESVRKLKELLRKSQQHGEESILQGEDLHARLTNPKGLNIRTSIAAEK--A 1997 Query: 1507 ELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQ 1566 +L + +++ K +E+++ + Q E+ L+ + ++ K S + TK+ Sbjct: 1998 KLEEEVQQLQLKISELESQVSCQAAELSKWKSRAIKLK---AKTKPELDKPGSPCTPTKR 2054 Query: 1567 GRDEQLDNTMNKELLDAVPRAELD 1590 G T + LL + R LD Sbjct: 2055 G---LCSTTESSHLLSSPKRKVLD 2075 Score = 140 bits (339), Expect = 3e-31 Identities = 261/1378 (18%), Positives = 571/1378 (41%), Gaps = 107/1378 (7%) Query: 216 QQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSL----EEANKLLEAARFEISLEH 271 +Q+ + ++ +++E E +E Q+LLKD+E K V + EE +K L+ E++ E Sbjct: 587 KQLEQSEQQKLSLE-EKINEMQQLLKDLEEKLVDSENSRETEEEISKELQEQLNELNREL 645 Query: 272 SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELL 331 E EQ L + + E + +E+ + A + I+ Sbjct: 646 QCERAEKEQNVHSSTETERLISSLTAERDQFRAELQDNVEKAAEAQ-AVLHSFQDDIQHH 704 Query: 332 EHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSS 391 N + + +++ ++ + + E + V + +R+SG +++ L++ Sbjct: 705 RQKNADLMKLSEQKDSDIENLSRELQRVCDELAE-----ARRSGEE-ERQLQPVIDSLTA 758 Query: 392 ETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQ 451 E Q +N+ E +L+ +I L ++ + + ++ + Q Sbjct: 759 EQDQQGRFAILNR-EKEELQEIIDVLRQEKQQLKAELEDRMELIEQLQTSLQAANDQRIQ 817 Query: 452 LQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQ 511 L+ E Q++ E +I + + + E ++ EQ KQ++ D N+K +K E+Q Sbjct: 818 LEDELQRNSE--LIIEIQCHFGRLEE--ELLEQ-KQKMAD-----NMKLWEQKESDLEQQ 867 Query: 512 ITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKV 571 T L +++++A L L++ +T + + ++ +V L+++ L + V Sbjct: 868 RTSLTEQLESAQ------SERDALMLEKDSRTHTYTEEKEELHRNLVTLSKDREELQEMV 921 Query: 572 AELEEEKGNLQLHLVD-YDSGRMIESDVYKKMIEMENL---AETRLKAISLLESQKFDLV 627 L +EK L+ L D + + ++ + E+ L E ++ I L+ + ++ Sbjct: 922 EMLRQEKQQLRTELEDRMEMLQQLQQHLESSKEEVNQLKSDLEENVELIQCLKEELLNIK 981 Query: 628 QELHILQQKYD-EVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLK 686 E L + D + L + S LQS + L+ ++ AL K+ L + +L Sbjct: 982 AERDALWSEKDASCSNSLQEKSDLQSRLTSLTEEKEELQSRLVALGEDKEALQNSLISLT 1041 Query: 687 LDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSK 746 +KE+L + L +KE++ ++L + D+ L ++ EK L +++ + K Sbjct: 1042 EEKEELQSHLTSLSKEKEELQSRLMALGEYKEDVKSSLMSLTEEK-EALQSRLMALGEDK 1100 Query: 747 IQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYL 806 Q + + +E+ E ++S L ++ S+ + + + +L+ + LG Sbjct: 1101 EALQSSVQSLSKEK----EELQSRLMALGEDKADVKSSLMSLTEEKEALQSRLMALGEDK 1156 Query: 807 QEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQ 866 + Q + + +++EL +RL L + V+ + + E +ELQ L +E +LQ Sbjct: 1157 EALQSSVQSLSKEKEELQSRLMALGEDKEDVKSSFMSLTEEKEELQSHLTALKKE--DLQ 1214 Query: 867 ISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIE 926 SL + + AL +++ L E E Q+ ++ L S K + + K +++ Sbjct: 1215 SSLMSLTEEKEAL--QSHLMALGE-EKEALQSSVQSL-SKEKEELQSRLMALGEDKADVK 1270 Query: 927 DLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNL 986 + + E L+++ E ++ L + +E ++ + +L E+L + L Sbjct: 1271 SSFMSLTEEKEELQSHLTSLSKEKEDLHSHLASLVEEKEELQSRLVSLGEEKEDLQRSLL 1330 Query: 987 ELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDY 1046 L + +K++ QS ++ ++K LK + E + + + N+ +S + Sbjct: 1331 SLTE---EKEELQS------HLTSLSKEKEELKSRLESLCEEKEALQNSLMSLSGEKEEL 1381 Query: 1047 ESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNI 1106 +S L T L EE Q++ + L KQH LQ ++E+ D + + + + + +M+ Sbjct: 1382 QSNL----TSLSEEREEFQKILEMLRQEKQH---LQAEMQERVDSL-QTEISTVNKKMDD 1433 Query: 1107 PKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNT 1166 KTE + S E S A++ + +E+EE + +++ + +L T Sbjct: 1434 IKTERDGLMSEKE-ASCWASSQEQELQSRLTSLR----EEKEEMSELLEMVKREEQQLRT 1488 Query: 1167 ELQECYTKIIQLE--TLNTELTGHDVVNQEQINQLKSKLEQLNTENDNL-LSTV------ 1217 E+ +C +Q E TL +L G +QE +++++L L E + L +S + Sbjct: 1489 EM-KCKLVALQTEVRTLTEKLQGISETSQEN-EEMQNRLASLGIEKEELQISALQQETDG 1546 Query: 1218 ----AELRSSI---SSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQ 1270 AEL+ + +S++ ++ L K + + D K E F + Sbjct: 1547 GEREAELQQLLVEANSSIAALQDQLDRLIKNPIMSQLQDSNKQIQEFLGTFQQFIEACSR 1606 Query: 1271 LLDSVQSSTQEETN---KIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEI 1327 + +VQ+ Q N K V S Q + + L+ L + Q ++ R+ Sbjct: 1607 MKVTVQNEAQRVNNPCPKFVPKSSRKSYSTVCQLRIQTLQCLLNTMEYLQEQAQVYRNLF 1666 Query: 1328 ED----EKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILN-INEENAQLKKSSX 1382 ED +++ F ++ + ++ + +++ N +KK Sbjct: 1667 EDLLKKDRLTFEEKCLQDVLLCRDQTYSFSVRDEDFNKLWRYRLTELLDKRNVYMKKMQT 1726 Query: 1383 XXXXXXXXXXXRVNDAEAKVLE---LTHQLELK---DSEIYQKTHEYTITLTQRNDEFEN 1436 N+ A+V E QL+ K D + + + + RN + Sbjct: 1727 IWEKLWANMSYFTNELSAEVREHESFKEQLQAKVGLDQILGGELQRRSTMVETRNIHLQQ 1786 Query: 1437 VRQQLVEYEKRIEDLTYEKESELAILR------LKMHENANHYETMQKESEIERVKLIEE 1490 +R++ + ++ L + +SEL R L+ ++T Q ++++ + ++ Sbjct: 1787 LREENSNMCEELKCLQVQNDSELREERSRRCSMLQEEVQGAAFDTQQLLLKLQQAE--DK 1844 Query: 1491 LNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVR 1548 + + E L K +++ L T +QT L++ ++ ++ I L+N ++ Sbjct: 1845 VRLMNAEKQQLEKDQLQVHGRLSSHKEATQLLQTELQDSRAQVQDQDNTIQTLRNQLK 1902 Score = 122 bits (294), Expect = 8e-26 Identities = 248/1327 (18%), Positives = 537/1327 (40%), Gaps = 91/1327 (6%) Query: 249 RISSLEEANKLLEAARFEISL--EHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEE 306 +I LE+ N LL E+ E L +E + A + E C+E Sbjct: 352 QIGKLEKENALLSKELQEMKEVEEFESLEEEFRKEHEDVLQNEICDLRRAVEGSELQCQE 411 Query: 307 KTEIEEKGSLEIANMTELTKKIELL--EHLNCQIRQTNKELENKLATMGTESKAVSSPSK 364 E ++E+ ++ ++++ + + L ++ + + L + +G ++K + + Sbjct: 412 LQNKLESVTVELKKKSDFAEELQTMNGKDLVQEVAELRRSLHDAEG-LGRDAKKEWAILR 470 Query: 365 KGSPLISRKSGRNTAS--KMKSPWSQLSSETLNQDTDKKINKNEIAK-LEMVIQSLNK-- 419 + + TAS KM++ L + + + K + ++ K L + K Sbjct: 471 SQNLSLEESVVTLTASHNKMEAEVGSLRHQLSVEKSHNKQMQTDLQKELNVAFDENTKLT 530 Query: 420 DLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIA 479 L+D + + D K+ L A + E + SL + + + + Sbjct: 531 ALLDGKVPKNLIDAVELERSAANLTKE-LTASREAEEALRGQLASLQVLPDQVQHLGKQL 589 Query: 480 KVQEQLKQELNDEIKDVN--VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKL 537 + EQ K L ++I ++ +KDL EKL +E + +EI + + + N +L+ Sbjct: 590 EQSEQQKLSLEEKINEMQQLLKDLEEKLVDSENS-RETEEEISKELQEQLN-ELNRELQC 647 Query: 538 KQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESD 597 ++ +K N +++ + I LT E ++ + E+ Q L + Sbjct: 648 ERAEKE-QNVHSSTETERLISSLTAERDQFRAELQDNVEKAAEAQAVLHSFQDDIQHHR- 705 Query: 598 VYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCS 657 +K ++ L+E + I L + + EL ++ +E I L ++Q Sbjct: 706 --QKNADLMKLSEQKDSDIENLSRELQRVCDELAEARRSGEEERQLQPVIDSLTAEQ--- 760 Query: 658 EIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQEN 717 + + L+ K+EL +I+ L+ +K+QL ++D E + LQ + Sbjct: 761 -----DQQGRFAILNREKEELQEIIDVLRQEKQQLKAELEDRMELIEQLQTSLQAANDQR 815 Query: 718 MDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFG-IDAKIQERDLYIENIESELSKYKS 776 + L D+L++ SEL+ +IQ FG ++ ++ E+ + + + ++ Sbjct: 816 IQLEDELQRN-----SELII--------EIQCHFGRLEEELLEQK---QKMADNMKLWEQ 859 Query: 777 RICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRV 836 + LE+ + ++ S + + D L + EK YT +++EL +R V + DR Sbjct: 860 KESDLEQQRTSLTEQLESAQSERDAL---MLEKDSRTHTYTEEKEEL-HRNLVTLSKDRE 915 Query: 837 VEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKAN--RTDLAESES- 893 ++++E+ Q+K Q+ E +++ L +QQH + E+ N ++DL E+ Sbjct: 916 ELQEMVEMLR-----QEKQQLRTELEDRMEM-LQQLQQHLESSKEEVNQLKSDLEENVEL 969 Query: 894 -TKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFN--TQIESAIRDKKV-LNEK 949 + +L ++++ + E +E DL+ T+ + ++ + V L E Sbjct: 970 IQCLKEELLNIKAERDALWSEKDASCSNSLQEKSDLQSRLTSLTEEKEELQSRLVALGED 1029 Query: 950 YEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYIN 1009 E + L + +E ++++ +L+ EEL + L + ++ + ++ TE+ Sbjct: 1030 KEALQNSLISLTEEKEELQSHLTSLSKEKEEL-QSRLMALGEYKEDVKSSLMSLTEEKEA 1088 Query: 1010 EINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSK 1069 ++L AL + K E + + Q ++ + S + A + L ++ EE + + Sbjct: 1089 LQSRLMALGEDK-EALQSSVQSLSKEKEELQSRLMALGEDKADVKSSLMSLTEEKEALQS 1147 Query: 1070 QLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVD 1129 +L+ + E LQ V+ + +EL+ + + + +S T E ++ + Sbjct: 1148 RLMALGEDKEALQSSVQSLSKEKEELQSRLMALGEDKEDVKSSFMSLTEE--KEELQSHL 1205 Query: 1130 XXXXXXXXXXXXLKVQEEEEFIQ--------ERSVLQEQSAKLNTELQECYTKIIQLETL 1181 + + EE+E +Q E+ LQ L+ E +E ++++ L Sbjct: 1206 TALKKEDLQSSLMSLTEEKEALQSHLMALGEEKEALQSSVQSLSKEKEELQSRLMALGED 1265 Query: 1182 NTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQ 1241 ++ + E+ +L+S L L+ E ++L S +A L + R + E K+ Sbjct: 1266 KADVKSSFMSLTEEKEELQSHLTSLSKEKEDLHSHLASLVEE-KEELQSRLVSLGE-EKE 1323 Query: 1242 HLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQD 1301 L + + + EL+ L++ + E+L ++S +E K + SL + ++ Sbjct: 1324 DLQRSLLSLTEEKEELQSHLTSLSKEKEELKSRLESLCEE---KEALQNSLMSLSGEKEE 1380 Query: 1302 KEEHLRNLQEKYADVINQIEILRSE---IEDEKVAFXXXXXXXXXXXXXXXXDLRTENQS 1358 + +L +L E+ + +E+LR E ++ E D++TE Sbjct: 1381 LQSNLTSLSEEREEFQKILEMLRQEKQHLQAEMQERVDSLQTEISTVNKKMDDIKTERDG 1440 Query: 1359 YKQMQEQSI-LNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIY 1417 +E S + E+ Q + +S + E + L + E+K + Sbjct: 1441 LMSEKEASCWASSQEQELQSRLTSLREEKEEMSELLEMVKREEQQL----RTEMKCKLVA 1496 Query: 1418 QKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQ 1477 +T TLT++ Q+ E + R+ L EKE EL I L+ + E Sbjct: 1497 LQTE--VRTLTEKLQGISETSQENEEMQNRLASLGIEKE-ELQISALQQETDGGEREAEL 1553 Query: 1478 KESEIERVKLIEELNVKITESVS--LNKQVAELNKALEEEVAKTNEMQTALENQEIEIVT 1535 ++ +E I L ++ + + Q+ + NK ++E + + A ++ + Sbjct: 1554 QQLLVEANSSIAALQDQLDRLIKNPIMSQLQDSNKQIQEFLGTFQQFIEACSRMKVTVQN 1613 Query: 1536 LNDEITN 1542 + N Sbjct: 1614 EAQRVNN 1620 Score = 111 bits (266), Expect = 2e-22 Identities = 212/1140 (18%), Positives = 477/1140 (41%), Gaps = 87/1140 (7%) Query: 451 QLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEE 510 QLQ E + ++ + + V T++ V E LK ND + +L EKL+S + Sbjct: 24 QLQREQEDRIKNLTKLLV-TSSNLVPFKKSPAETLKLNRNDPLWRKRAAELEEKLQSEAQ 82 Query: 511 QITQLNDEIDAANKNM----IKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHH 566 Q + ++I ++ + ++++S + K + ++K+ + + ++ ++ ++ H Sbjct: 83 QKHEALEKIHSSEQRAAELELQLQSEAQQKHEALEKSHSSEQRAAELELQLQSEAQQKHE 142 Query: 567 LSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDL 626 +K E+ L+L L + + K + AE L+ S + Q + Sbjct: 143 ALEKSHSSEQRAAELELQL--QSEAQQKHEALEKSHSSEQRAAELELQLQSEAQ-QNHEA 199 Query: 627 VQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLK 686 +++ H +Q+ E+E +L Q ++ Q ++ H EQ A EL L +++ Sbjct: 200 LEKSHSSEQRAAELELQL----QSEAQQKHEALEKSHSSEQRAA------ELELQLQSEA 249 Query: 687 LDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLE-KMSAEKISELLAKINHEE-- 743 K + I E ++ +LQ+ Q+ + TDK E + ++ L++ +H + Sbjct: 250 QQKHEALEKIHSSEQRAAELELQLQSEAQQKHEATDKAELLLRVAELERQLSERSHVQGG 309 Query: 744 -QSKIQTQFG-----IDAKIQERDLYI---ENIESELSKYKSRICRLEESIAVMEDRRYS 794 +++ F +A E+DL + + ++ EL + +I +LE+ A++ Sbjct: 310 ADEQVRRDFAETIQLCEALASEKDLMVTERDYLKQELGMFLEQIGKLEKENALLSKELQE 369 Query: 795 LERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKK 854 + ++ ++ S +E +K + + + ++E+ + + + ++ ++E EL+KK Sbjct: 370 M-KEVEEFESLEEEFRKEHED--VLQNEICDLRRAVEGSELQCQELQNKLESVTVELKKK 426 Query: 855 NQILLE-ENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHE 913 + E + N + + ++ + +L + A+ E ++Q LE ++ +T Sbjct: 427 SDFAEELQTMNGKDLVQEVAELRRSLHDAEGLGRDAKKEWAILRSQNLSLEESVVTLTAS 486 Query: 914 HQTLIVQKKKEIEDLEIE--FNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNI 971 H + + L +E N Q+++ + +K LN +++N + L+ ++ KN I Sbjct: 487 HNKMEAEVGSLRHQLSVEKSHNKQMQTDL--QKELNVAFDENTKLTALLDGKVP--KNLI 542 Query: 972 ENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYI-NEINKLNALLKQKDEEIIALNQ 1030 + + + N + EL ++ + + Q + +++ L L+Q +++ ++L + Sbjct: 543 DAVELERSAAN-LTKELTASREAEEALRGQLASLQVLPDQVQHLGKQLEQSEQQKLSLEE 601 Query: 1031 KINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDS-KQHNEELQILVREQD 1089 KIN Q ++ D E KL EN E + +SK+L + + N ELQ E++ Sbjct: 602 KINEMQ----QLLKDLEEKLVD----SENSRETEEEISKELQEQLNELNRELQCERAEKE 653 Query: 1090 DQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEE-E 1148 + E TE +I S T E A D Q++ + Sbjct: 654 QNVHSSTE-----------TERLISSLTAERDQFRAELQDNVEKAAEAQAVLHSFQDDIQ 702 Query: 1149 EFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNT 1208 Q+ + L + S + +++++ +L+ + EL +E+ QL+ ++ L Sbjct: 703 HHRQKNADLMKLSEQKDSDIENLSR---ELQRVCDELAEARRSGEEE-RQLQPVIDSLTA 758 Query: 1209 ENDN-----LLSTVAELRSSISSAVDQRGFEI-AELW-KQHLAQREADFQKTEHELRVQL 1261 E D +L+ E I + Q ++ AEL + L ++ + ++ R+QL Sbjct: 759 EQDQQGRFAILNREKEELQEIIDVLRQEKQQLKAELEDRMELIEQLQTSLQAANDQRIQL 818 Query: 1262 SAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIE 1321 + +L+ +Q +++ +Q + KL +++E +L+++ + Q+E Sbjct: 819 EDELQRNSELIIEIQCHFGRLEEELLEQKQKMADNMKLWEQKE--SDLEQQRTSLTEQLE 876 Query: 1322 ILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSS 1381 +SE + + +L T ++ +++QE + + +E QL+ Sbjct: 877 SAQSERDALMLEKDSRTHTYTEEKEELHRNLVTLSKDREELQEM-VEMLRQEKQQLRTEL 935 Query: 1382 XXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEF------- 1434 + ++ +V +L LE ++ E+ Q E + + D Sbjct: 936 EDRMEMLQQLQQHLESSKEEVNQLKSDLE-ENVELIQCLKEELLNIKAERDALWSEKDAS 994 Query: 1435 -ENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNV 1493 N Q+ + + R+ LT EKE EL + + E+ + E+ +L L Sbjct: 995 CSNSLQEKSDLQSRLTSLTEEKE-ELQSRLVALGEDKEALQNSLISLTEEKEELQSHLTS 1053 Query: 1494 KITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSK 1553 E L ++ L + E+ + + E + ++ L ++ LQ+ V++ S + Sbjct: 1054 LSKEKEELQSRLMALGEYKEDVKSSLMSLTEEKEALQSRLMALGEDKEALQSSVQSLSKE 1113 Score = 77.4 bits (182), Expect = 3e-12 Identities = 170/888 (19%), Positives = 364/888 (40%), Gaps = 71/888 (7%) Query: 237 QRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLA 296 Q L K+ E R+ +L E ++++ ++ E L L L+ Sbjct: 1108 QSLSKEKEELQSRLMALGEDKADVKSSLMSLTEEKEALQSRLMALGEDKEALQSSVQSLS 1167 Query: 297 KQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTES 356 K+ E E+K ++ + M+ +K EL HL ++ +L++ L ++ E Sbjct: 1168 KEKEELQSRLMALGEDKEDVKSSFMSLTEEKEELQSHLTALKKE---DLQSSLMSLTEEK 1224 Query: 357 KAVSSP-SKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQ 415 +A+ S G + +S + SK K +L S + DK K+ L + Sbjct: 1225 EALQSHLMALGEEKEALQSSVQSLSKEK---EELQSRLMALGEDKADVKSSFMSLTEEKE 1281 Query: 416 SLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQL-QLEHQQHMEGPSLIHVGTNTED 474 L L + EK+ K+ L ++L L ++ SL+ + E+ Sbjct: 1282 ELQSHLTS---LSKEKEDLHSHLASLVEEKEELQSRLVSLGEEKEDLQRSLLSLTEEKEE 1338 Query: 475 ----VNEIAKVQEQLKQELND--EIKDVNVKDLIEKLKSAEE---QITQLNDEIDAANKN 525 + ++K +E+LK L E K+ L+ EE +T L++E + K Sbjct: 1339 LQSHLTSLSKEKEELKSRLESLCEEKEALQNSLMSLSGEKEELQSNLTSLSEEREEFQKI 1398 Query: 526 MIKVKSNHKLKLKQMQKTIDNF-SKVSDSNKEIVRL-TEELHHLSQKVAE--LEEEKGNL 581 + ++ + +MQ+ +D+ +++S NK++ + TE +S+K A ++ L Sbjct: 1399 LEMLRQEKQHLQAEMQERVDSLQTEISTVNKKMDDIKTERDGLMSEKEASCWASSQEQEL 1458 Query: 582 QLHLVDYDSGRMIESDVYKKMIEMENLAETRLKA-ISLLESQKFDLVQELHIL---QQKY 637 Q L + S++ + + E T +K + L+++ L ++L + Q+ Sbjct: 1459 QSRLTSLREEKEEMSELLEMVKREEQQLRTEMKCKLVALQTEVRTLTEKLQGISETSQEN 1518 Query: 638 DEVEDKLADI----SQLQSDQVCSEIKSVHLEEQIDAL--SASKKELALVIENLKLDKEQ 691 +E++++LA + +LQ + E E ++ L A+ AL + +L K Sbjct: 1519 EEMQNRLASLGIEKEELQISALQQETDGGEREAELQQLLVEANSSIAALQDQLDRLIKNP 1578 Query: 692 LYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQF 751 + ++D ++ + Q +I+ + ++ A++++ K + K + Sbjct: 1579 IMSQLQDSNKQIQEFLGTFQQFIEACSRMKVTVQN-EAQRVNNPCPKFVPKSSRKSYSTV 1637 Query: 752 GIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQK 811 +IQ + +E L + L E + ++ R + E K L L + + Sbjct: 1638 -CQLRIQTLQCLLNTME-YLQEQAQVYRNLFEDL--LKKDRLTFEEKC--LQDVLLCRDQ 1691 Query: 812 AYSEYTIQEDELVN----RLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQI 867 YS +++++++ RL L+D V K++ I ++L E L Sbjct: 1692 TYS-FSVRDEDFNKLWRYRLTELLDKRNVYMKKMQTIW---EKLWANMSYFTNE---LSA 1744 Query: 868 SLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIED 927 + + + L K + E + T + +L+++ E+ + +E++ Sbjct: 1745 EVREHESFKEQLQAKVGLDQILGGELQRRSTMVETRNIHLQQLREENSNMC----EELKC 1800 Query: 928 LEIEFNTQI-ESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNL 986 L+++ ++++ E R +L E+ + QL +LQ+ ++ + +N ++L K L Sbjct: 1801 LQVQNDSELREERSRRCSMLQEEVQGAAFDTQQLLLKLQQAEDKVRLMNAEKQQLEKDQL 1860 Query: 987 EL---IDKH---VQKQQTQSPDYTEQYINEINKLNALLKQKDE-----EIIALNQKINNA 1035 ++ + H Q QT+ D Q ++ N + L Q E ++ + + Sbjct: 1861 QVHGRLSSHKEATQLLQTELQDSRAQVQDQDNTIQTLRNQLKEAQVYRSVLIITAAVGTF 1920 Query: 1036 QVSYMSMVSDYE---SKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEE 1080 + ++ VS E +K+ +F L EE ++++ + L S+QH EE Sbjct: 1921 EGFCLTDVSSAEKCFAKIQKFKVLLNTKEESVRKLKELLRKSQQHGEE 1968 Score = 67.3 bits (157), Expect = 3e-09 Identities = 169/878 (19%), Positives = 349/878 (39%), Gaps = 86/878 (9%) Query: 691 QLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQ 750 QL L+ ++ED + L + + +L +K AE + K+N + + Sbjct: 17 QLLQEKDQLQREQEDRIKNLTKLLVTSSNLVP-FKKSPAETL-----KLNRNDPLWRKRA 70 Query: 751 FGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQ 810 ++ K+Q ++ + R LE + +++ K S+ E++ Sbjct: 71 AELEEKLQSEAQQKHEALEKIHSSEQRAAELELQLQSEAQQKHEALEK-----SHSSEQR 125 Query: 811 KAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQN------ 864 A E +Q + A+ H LE++ ++ E Q+K++ L + + + Sbjct: 126 AAELELQLQSEAQQKHEALEKSHSSEQRAAELELQLQS-EAQQKHEALEKSHSSEQRAAE 184 Query: 865 LQISL-SDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKK 923 L++ L S+ QQ++ AL EK++ + E + + + QL+ E+ K E Q+ Sbjct: 185 LELQLQSEAQQNHEAL-EKSHSS---EQRAAELELQLQS-EAQQKHEALEKSHSSEQRAA 239 Query: 924 EIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNK 983 E+E L+++ Q + +K +E+ +E Q EAQ + + L + V EL + Sbjct: 240 ELE-LQLQSEAQQKHEALEKIHSSEQRAAELELQLQSEAQQKHEATDKAELLLRVAELER 298 Query: 984 MNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMV 1043 E HVQ + + I AL +KD ++ + ++ + Sbjct: 299 QLSER--SHVQGGADEQ--VRRDFAETIQLCEALASEKDL-MVTERDYLKQELGMFLEQI 353 Query: 1044 SDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFE 1103 E + A + +L+ M+E + S + K+H + LQ ++I +L+ E Sbjct: 354 GKLEKENALLSKELQEMKEVEEFESLEEEFRKEHEDVLQ-------NEICDLRRAVEGSE 406 Query: 1104 MNIPKTEGMIISSTIE-----PMSDDANNVDXXXXXXXXXXXXLKVQEEE----EFIQER 1154 + + + + S T+E +++ ++ + + E + +E Sbjct: 407 LQCQELQNKLESVTVELKKKSDFAEELQTMNGKDLVQEVAELRRSLHDAEGLGRDAKKEW 466 Query: 1155 SVLQEQSAKLNTE---LQECYTKI-IQLETLNTELTGHDVVNQEQINQLKSKLEQLNTEN 1210 ++L+ Q+ L L + K+ ++ +L +L+ N++ L+ +L EN Sbjct: 467 AILRSQNLSLEESVVTLTASHNKMEAEVGSLRHQLSVEKSHNKQMQTDLQKELNVAFDEN 526 Query: 1211 DNLLSTV-AELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYE 1269 L + + ++ ++ AV+ A L K+ A REA E LR QL++ + + Sbjct: 527 TKLTALLDGKVPKNLIDAVELER-SAANLTKELTASREA-----EEALRGQLASLQVLPD 580 Query: 1270 QLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIED 1329 Q+ + Q E K+ SL+ K+ + ++ L++L+EK D N E EI Sbjct: 581 QVQHLGKQLEQSEQQKL-------SLEEKINEMQQLLKDLEEKLVDSENSRET-EEEISK 632 Query: 1330 EKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXX 1389 E +L E Q + +EQ++ + E + + Sbjct: 633 E--------------LQEQLNELNRELQCERAEKEQNVHSSTETERLISSLTAERDQFRA 678 Query: 1390 XXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIE 1449 V A A+ + H + QK + Q++ + EN+ ++L + Sbjct: 679 ELQDNVEKA-AEAQAVLHSFQDDIQHHRQKNADLMKLSEQKDSDIENLSRELQRVCDELA 737 Query: 1450 DLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELN 1509 + E E L+ + + + + + R K EEL +I + + KQ +L Sbjct: 738 EARRSGEEERQ-LQPVIDSLTAEQDQQGRFAILNREK--EELQ-EIIDVLRQEKQ--QLK 791 Query: 1510 KALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMV 1547 LE+ + ++QT+L+ + + L DE+ ++ Sbjct: 792 AELEDRMELIEQLQTSLQAANDQRIQLEDELQRNSELI 829 Score = 62.9 bits (146), Expect = 7e-08 Identities = 149/757 (19%), Positives = 311/757 (41%), Gaps = 79/757 (10%) Query: 838 EKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVE--KANRTD-LAESEST 894 +K L ++ E +LQ++ + ++ L ++ S++ + E K NR D L + Sbjct: 12 KKVLSQLLQEKDQLQREQEDRIKNLTKLLVTSSNLVPFKKSPAETLKLNRNDPLWRKRAA 71 Query: 895 KYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNI 954 + + +L+ E+ K HE I ++ +LE++ ++ + + + ++ Sbjct: 72 ELEEKLQS-EAQQK---HEALEKIHSSEQRAAELELQLQSEAQQKHEALEKSHSSEQRAA 127 Query: 955 EYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDY-TEQYINEIN- 1012 E QL+++ Q+ +E + + + ++ L+L + QK + + +EQ E+ Sbjct: 128 ELELQLQSEAQQKHEALEKSHSSEQRAAELELQLQSEAQQKHEALEKSHSSEQRAAELEL 187 Query: 1013 KLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLL 1072 +L + +Q E + + S+ S E + A+ +L++ ++ ++ Sbjct: 188 QLQSEAQQNHEAL----------EKSHSS-----EQRAAELELQLQSEAQQKHEALEKSH 232 Query: 1073 DSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXX 1132 S+Q EL++ ++ + Q E E + E + E + + S + + + + Sbjct: 233 SSEQRAAELELQLQSEAQQKHEALEKIHSSEQRAAELE-LQLQSEAQQKHEATDKAE--- 288 Query: 1133 XXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQL-ETLNTE----LTG 1187 L+V E E + ERS +Q + +++ + + IQL E L +E +T Sbjct: 289 -------LLLRVAELERQLSERSHVQ---GGADEQVRRDFAETIQLCEALASEKDLMVTE 338 Query: 1188 HDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQRE 1247 D + QE + ++ +L EN L + E++ V++ FE E ++ + E Sbjct: 339 RDYLKQE-LGMFLEQIGKLEKENALLSKELQEMKE-----VEE--FESLE--EEFRKEHE 388 Query: 1248 ADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNK--LQDKEEH 1305 Q +LR + E + ++L + ++S T E K E++ ++ K +Q+ E Sbjct: 389 DVLQNEICDLRRAVEGSELQCQELQNKLESVTVELKKKSDFAEELQTMNGKDLVQEVAEL 448 Query: 1306 LRNLQEKYA---DVINQIEILRSE---IEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSY 1359 R+L + D + ILRS+ +E+ V L E Sbjct: 449 RRSLHDAEGLGRDAKKEWAILRSQNLSLEESVVTLTASHNKMEAEVGSLRHQLSVEKSHN 508 Query: 1360 KQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQK 1419 KQMQ +N + K + + E LT +L E + Sbjct: 509 KQMQTDLQKELNVAFDENTKLTALLDGKVPKNLIDAVELERSAANLTKEL-TASREAEEA 567 Query: 1420 THEYTITLTQRNDEFENVRQQLVEYEKR---IEDLTYEKESELAILRLKMHENANHYETM 1476 +L D+ +++ +QL + E++ +E+ E + L L K+ ++ N ET Sbjct: 568 LRGQLASLQVLPDQVQHLGKQLEQSEQQKLSLEEKINEMQQLLKDLEEKLVDSENSRET- 626 Query: 1477 QKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTL 1536 E EI + +L E+LN LN+++ E+ V + E + + + E Sbjct: 627 --EEEISK-ELQEQLN-------ELNRELQCERAEKEQNVHSSTETERLISSLTAERDQF 676 Query: 1537 NDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLD 1573 E+ + N+ +A+ ++ H SF D + R + D Sbjct: 677 RAELQD--NVEKAAEAQAVLH-SFQDDIQHHRQKNAD 710 >UniRef50_Q22SA1 Cluster: Putative uncharacterized protein; n=1; Tetrahymena thermophila SB210|Rep: Putative uncharacterized protein - Tetrahymena thermophila SB210 Length = 1893 Score = 153 bits (372), Expect = 3e-35 Identities = 252/1390 (18%), Positives = 577/1390 (41%), Gaps = 90/1390 (6%) Query: 254 EEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEK 313 +E + L+ ++ L+ S L + Q SI+ + T E+K Sbjct: 342 KEIEESLKHENDDLKLKISMLHESYSQINKSMIGGAAGTKPDISFSIQKDLDIATTYEQK 401 Query: 314 GSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRK 373 L + K++E N + ++ N EL + + + V + +G + + Sbjct: 402 VLLIQKELERSHKELEDYRKKNQEAQKKNDELNHTCTQLNEQLNTVIQKTIEGKTV---Q 458 Query: 374 SGRNTASKMKSPWSQLSSETLNQDTDKKIN-KNEIAKLE--MVIQSLNKDLVDKEYVISE 430 ++K + + E Q + N KN+I++LE ++ + + + + Sbjct: 459 IDEYKLDQVKQQYERKLYEEQQQYSQNLQNMKNQISELETSLIQEKATTQKLQTDILNLT 518 Query: 431 KDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELN 490 D Q++ ++ S+ N E +N K+ E Sbjct: 519 NDQIIVGSNNTKSSPSYNNQQIENIKSEYENIISVQRQQFNQELLNVNQKIYELESSLTT 578 Query: 491 DEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKV 550 ++ + ++ I+ L + + +++ D + +++ N + K H+ L ++K + ++ Sbjct: 579 EKFNNKKLQGEIQNLSTLVAEQSRIYDPVASSSANSEETKRKHEEMLSNLRK--QHQEEI 636 Query: 551 SDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLA- 609 + + +I L +L + +L+ E N+ + ++ +S ++ E+ + K ++++ L Sbjct: 637 NRISSQIALLEYQLANEKTTNQKLQNEIQNISISQININSTKIPETQIQDKELQIQQLKK 696 Query: 610 ---ETRLKAISLLESQKFDLVQELHILQQKYDE-------VEDKLADISQLQSDQVCSEI 659 ET L E + + +++ IL+Q E +E ++ +IS + EI Sbjct: 697 QFEETVLNQKIAYEQEVQKMNKQVEILEQSLIEEKTNSKKLEYEIQNISCQYGNNNDEEI 756 Query: 660 KSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDK--EDIMNKLQNYIQEN 717 ++ L++Q++ L + L + +N++L + QL EN+ +++++++QN N Sbjct: 757 QN--LKKQVEELH--NQNLKINQQNMELTQTQLAMAQLANENNPNTDNLLSEIQNLKNLN 812 Query: 718 MDLTDKLEKMSAEKISELLAKINHEE---QSKIQTQFGIDAKIQER-DLYIENIESELSK 773 L K E++ K E+ + Q Q F + ++ER + + N + + Sbjct: 813 ETLNLKNEELVQAKEKEIQERTEEYRMIIQKMEQESFSVIQHVEERGEKEVRNQANNMDS 872 Query: 774 --YKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLM 831 Y+++I L E+I ++ + Q L E + Y +ED L+N + Sbjct: 873 ILYENQIEELNETIRQLQQQLEVQHVPNSQ--KQLTESPEVVRIYK-KEDNLINIQENFV 929 Query: 832 DHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVE-KANRTDL-- 888 + D QL + + + + + K +++ + + ++ ++Q YN + + N + + Sbjct: 930 NQDEEDSSQLQQKDEQQEIISLKEEVVKQREECDKLK-EKIEQEYNTNEDLRQNLSKIVT 988 Query: 889 -AESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLN 947 +E + TKY+ Q+ D+ES L H I +KK+ IEDLE E ++ + Sbjct: 989 ESEEQDTKYKKQISDIESKL----FLHIKEIAEKKQLIEDLEKSKKALAEQVFSYEEKEH 1044 Query: 948 EKYEKNIEYVTQL-------EAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQ- 999 +++ +E QL + Q+QE + + + N+M + + +Q+ Q++ Sbjct: 1045 NLHQQVVEAKEQLAKIQAETKFQIQEAEKRHSTSSSQILNENEMKISKLKSEIQQVQSEY 1104 Query: 1000 ---SPDYTEQYINEINKLNA---LLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQF 1053 +QY +IN+LN+ L + +E AL ++ + + +E ++A+ Sbjct: 1105 QLKIQQSEQQYTTQINQLNSQIQTLTNQTQEKNALIEEKERKIEEQIQVAKKFEERIAEM 1164 Query: 1054 TTKLENM---EEEMQRVSKQLLD--SKQHNEELQILVREQDDQIKELKETKLTFEMNIPK 1108 + E++ +++++ SKQL + K++ +L + + EL+ +K ++ + Sbjct: 1165 VKEREDLLKHDKDIELQSKQLKEIMEKEYKHQLDVQISLAKKLETELEASKQKYQSQVDL 1224 Query: 1109 TEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQ----------ERSVLQ 1158 + + + + N +++E+ +Q E+++ Sbjct: 1225 FNEQVKKCQVLEVQLNENKEKQQQLELQWNNQKKEIEEQNNQVQFELKNKLSELEKTIAS 1284 Query: 1159 E--QSAKLNTELQECYTKIIQLE-TLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLS 1215 + + +L +L++ ++ Q+ LN + T ++ +E + L SK++Q++ EN+ + Sbjct: 1285 QTHEEHQLKNDLEKYQNQLAQIAGQLNQKETQLNLFKKEN-SALSSKIQQIDEENN---T 1340 Query: 1216 TVAELRSSISSAVDQRGFEIAELWKQHLAQRE-ADFQKTEHELRV--QLSAFESKYEQLL 1272 EL I Q+ E+ + + + + Q E +K E++L ++ + YE LL Sbjct: 1341 EKQELTQKIEKLEAQQA-ELQQKYDKQVKQYERVKKEKEENDLLADEEIHKLKQNYEALL 1399 Query: 1273 DSVQSSTQEETNKIVTMEQVTSLQNKLQD-KEEHLRNLQEKYADVI-NQIEILRSEIEDE 1330 +S +++ ++ + +T +Q D K + +K + ++E L+ ++ ++ Sbjct: 1400 ESEKAAKEDVKKEFITKVDELKIQVARHDTKTRQTEDKHQKQVKTLEKEVESLK-QLNNK 1458 Query: 1331 KVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXX 1390 K+ L ++ + +Q + NEE L + Sbjct: 1459 KIETMKTIQETCKKLEEEKGQLESQYKKKEQKFIDELKEKNEEIEVLTQQKKKINEIQNE 1518 Query: 1391 XXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIED 1450 ++ + KV EL+ E E+ Q++ E I++ + + +Q + EYE +I + Sbjct: 1519 LQEKLIAEQKKVSELSENQEKLAKEL-QQSEEKKISI--EKEWIQKNQQTIAEYESKISE 1575 Query: 1451 LTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNK 1510 E E L+ + + + + E E + LN KI S K E K Sbjct: 1576 KDAEFEKILSSKQGDSSQQIQELSSKNMKQEKEFREKENNLNNKINTLQSSVKNHEEKLK 1635 Query: 1511 ALEEEVAK-TNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRD 1569 +LEEE +K + ++ + EI T I QN + A +I++ + + + Sbjct: 1636 SLEEENSKLSTQLSEKIAVLNKEIDTHKASIKENQNQIEAFEKEIKEKNQIIKNLESDKS 1695 Query: 1570 EQLDNTMNKE 1579 + + T+ +E Sbjct: 1696 DLEEKTLKQE 1705 Score = 145 bits (352), Expect = 8e-33 Identities = 275/1419 (19%), Positives = 619/1419 (43%), Gaps = 177/1419 (12%) Query: 320 NMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTA 379 N+ + +I LE Q + T ++L+ + + + V S + K SP + + N Sbjct: 485 NLQNMKNQISELETSLIQEKATTQKLQTDILNLTNDQIIVGSNNTKSSPSYNNQQIENIK 544 Query: 380 SKMKSPWS----QLSSETLNQ-------DTDKKINKNEIAKLEMVIQSLNKDLVDKEYVI 428 S+ ++ S Q + E LN ++ K KL+ IQ+L+ + ++ + Sbjct: 545 SEYENIISVQRQQFNQELLNVNQKIYELESSLTTEKFNNKKLQGEIQNLSTLVAEQSRIY 604 Query: 429 SEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQE 488 + + +++ L+ +HQ+ + S + NE Q+ + Sbjct: 605 DPVASSSANSEETKRKHEEMLSNLRKQHQEEINRISSQIALLEYQLANEKTTNQKLQNEI 664 Query: 489 LNDEIKDVNV------------KDL-IEKLKSA------------EEQITQLNDEIDAAN 523 N I +N+ K+L I++LK E+++ ++N +++ Sbjct: 665 QNISISQININSTKIPETQIQDKELQIQQLKKQFEETVLNQKIAYEQEVQKMNKQVEILE 724 Query: 524 KNMIKVKSNHKLKLKQMQKTIDNFSKVSDSN-KEIVRLTEELHHLSQKVAELEEEKGNLQ 582 +++I+ K+N K ++Q + +D + + + EELH+ + K+ + E Q Sbjct: 725 QSLIEEKTNSKKLEYEIQNISCQYGNNNDEEIQNLKKQVEELHNQNLKINQQNMELTQTQ 784 Query: 583 LHLVDYDSGRMIESD-VYKKMIEMENLAET-RLKAISLLESQKFDL---VQELHILQQKY 637 L + + +D + ++ ++NL ET LK L+++++ ++ +E ++ QK Sbjct: 785 LAMAQLANENNPNTDNLLSEIQNLKNLNETLNLKNEELVQAKEKEIQERTEEYRMIIQKM 844 Query: 638 DE----VEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELA--LVIENLKLDKEQ 691 ++ V + + + + + + S+ E QI+ L+ + ++L L ++++ ++Q Sbjct: 845 EQESFSVIQHVEERGEKEVRNQANNMDSILYENQIEELNETIRQLQQQLEVQHVPNSQKQ 904 Query: 692 LYGT--IKDLENDKEDIMNKLQNYI-QENMDLTDKLEKMSAEKISELLAKI--NHEE--- 743 L + + + +++++N +N++ Q+ D + +K ++I L ++ EE Sbjct: 905 LTESPEVVRIYKKEDNLINIQENFVNQDEEDSSQLQQKDEQQEIISLKEEVVKQREECDK 964 Query: 744 -QSKIQTQFGIDAKIQER-DLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQ 801 + KI+ ++ + +++ + E + +KYK +I +E + + + E+K Q Sbjct: 965 LKEKIEQEYNTNEDLRQNLSKIVTESEEQDTKYKKQISDIESKLFL--HIKEIAEKK--Q 1020 Query: 802 LGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVE--KQLLEIEHENK----ELQKKN 855 L L++ +KA +E +E + L H +VVE +QL +I+ E K E +K++ Sbjct: 1021 LIEDLEKSKKALAEQVFSYEEKEHNL-----HQQVVEAKEQLAKIQAETKFQIQEAEKRH 1075 Query: 856 -----QILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRI 910 QIL E + S++QQ V+ + + +SE +Y TQ+ L S ++ + Sbjct: 1076 STSSSQILNENEMKISKLKSEIQQ-----VQSEYQLKIQQSEQ-QYTTQINQLNSQIQTL 1129 Query: 911 THEHQ---TLIVQKKKEIED-LEI--EFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQL 964 T++ Q LI +K+++IE+ +++ +F +I +++++ L K++K+IE ++ ++ Sbjct: 1130 TNQTQEKNALIEEKERKIEEQIQVAKKFEERIAEMVKEREDLL-KHDKDIELQSKQLKEI 1188 Query: 965 QEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQY----INEINKLNALLKQ 1020 E K L++ + K+ EL + QK Q+Q + EQ + E+ KQ Sbjct: 1189 ME-KEYKHQLDVQISLAKKLETEL-EASKQKYQSQVDLFNEQVKKCQVLEVQLNENKEKQ 1246 Query: 1021 KDEEIIALNQKI------NNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQL--L 1072 + E+ NQK N Q + +S+ E +A T + ++ ++++ QL + Sbjct: 1247 QQLELQWNNQKKEIEEQNNQVQFELKNKLSELEKTIASQTHEEHQLKNDLEKYQNQLAQI 1306 Query: 1073 DSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXX 1132 + + +E Q+ + ++++ K ++ E N K E ++ IE + + Sbjct: 1307 AGQLNQKETQLNLFKKENSALSSKIQQIDEENNTEKQE---LTQKIEKLEAQQAELQQKY 1363 Query: 1133 XXXXXXXXXLKVQEEE------EFIQE-----RSVLQEQSAKLNTELQECYTKI----IQ 1177 +K ++EE E I + ++L+ + A +E TK+ IQ Sbjct: 1364 DKQVKQYERVKKEKEENDLLADEEIHKLKQNYEALLESEKAAKEDVKKEFITKVDELKIQ 1423 Query: 1178 LETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRG-FE-- 1234 + +T+ + +Q+Q+ L+ ++E L N+ + T+ ++ + +++G E Sbjct: 1424 VARHDTKTRQTEDKHQKQVKTLEKEVESLKQLNNKKIETMKTIQETCKKLEEEKGQLESQ 1483 Query: 1235 --------IAELWKQH-----LAQREADFQKTEHELRVQLSAFESKYEQLLDSVQS---S 1278 I EL +++ L Q++ + ++EL+ +L A + K +L ++ + Sbjct: 1484 YKKKEQKFIDELKEKNEEIEVLTQQKKKINEIQNELQEKLIAEQKKVSELSENQEKLAKE 1543 Query: 1279 TQEETNKIVTMEQ---------VTSLQNKLQDKE-EHLRNLQEKYADVINQIEILRSEIE 1328 Q+ K +++E+ + ++K+ +K+ E + L K D QI+ L S+ Sbjct: 1544 LQQSEEKKISIEKEWIQKNQQTIAEYESKISEKDAEFEKILSSKQGDSSQQIQELSSKNM 1603 Query: 1329 DEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSI---LNINEENAQLKKSSXXXX 1385 ++ F ++ + K ++E++ ++E+ A L K Sbjct: 1604 KQEKEFREKENNLNNKINTLQSSVKNHEEKLKSLEEENSKLSTQLSEKIAVLNKEIDTHK 1663 Query: 1386 XXXXXXXXRVNDAEAKVLE---LTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLV 1442 ++ E ++ E + LE S++ +KT + + + + E + Sbjct: 1664 ASIKENQNQIEAFEKEIKEKNQIIKNLESDKSDLEEKTLKQEEKIVLISTQLEQTKASKK 1723 Query: 1443 EYEKRIEDLTYEKESELAILRLKMHENANHY----ETMQKESEIERVKLIEELNV----K 1494 E E ++ EKE+E I+ ++ Y E +Q S + ++L K Sbjct: 1724 EIEDKLSRKIKEKETEQNIISQDYNQKIQVYKQTIEHLQNNSRQGDINFSQDLKFSQISK 1783 Query: 1495 ITESVSLNK---------QVAELNKALEEEVAKTNEMQTALEN--QEIEIVTLNDEITNL 1543 IT+++S N EL++ L VA ++ + ++ + + E ++ +++ + Sbjct: 1784 ITDNLSDNNSHDEQADKLSGKELSQRLMSGVAALSQSRASVSSIRSKEETRSMYKKLSQM 1843 Query: 1544 QNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLD 1582 A S + +VS K D ++NT N+E +D Sbjct: 1844 SMATAAMMSVKRDYVSLKELAKSIDDHDVNNTSNQEDID 1882 Score = 110 bits (265), Expect = 3e-22 Identities = 219/1133 (19%), Positives = 476/1133 (42%), Gaps = 101/1133 (8%) Query: 471 NTEDVNEIAKVQEQLKQELNDE---IKDVNVKDLI---EKLKSAEEQITQLNDEI----- 519 NT N I+ + +++ +L DE + + N+K + +K K EE + ND++ Sbjct: 301 NTSKFNSISMIPDKVSDKLIDEFQKLTESNLKFFMQNKQKWKEIEESLKHENDDLKLKIS 360 Query: 520 ------DAANKNMIKVKSNHKLKLK-QMQKTIDNFS----KVSDSNKEIVRLTEELHHLS 568 NK+MI + K + +QK +D + KV KE+ R +EL Sbjct: 361 MLHESYSQINKSMIGGAAGTKPDISFSIQKDLDIATTYEQKVLLIQKELERSHKELEDYR 420 Query: 569 QKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQ 628 +K E +++ L H + ++ + V +K IE + + K L+ K + Sbjct: 421 KKNQEAQKKNDELN-HTCTQLNEQL--NTVIQKTIEGKTVQIDEYK----LDQVKQQYER 473 Query: 629 ELHILQQKYDE-VEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKL 687 +L+ QQ+Y + +++ IS+L++ + + K+ + Q D L+ + ++ + N K Sbjct: 474 KLYEEQQQYSQNLQNMKNQISELETSLI--QEKATTQKLQTDILNLTNDQIIVGSNNTKS 531 Query: 688 DKEQLYGTIKDLENDKEDIMN-KLQNYIQENMDLTDKL----EKMSAEKIS--ELLAKIN 740 I++++++ E+I++ + Q + QE +++ K+ ++ EK + +L +I Sbjct: 532 SPSYNNQQIENIKSEYENIISVQRQQFNQELLNVNQKIYELESSLTTEKFNNKKLQGEIQ 591 Query: 741 H-----EEQSKI-----QTQFGIDAKIQERDLYIENI----ESELSKYKSRICRLEESIA 786 + EQS+I + + ++ + + N+ + E+++ S+I LE +A Sbjct: 592 NLSTLVAEQSRIYDPVASSSANSEETKRKHEEMLSNLRKQHQEEINRISSQIALLEYQLA 651 Query: 787 VMEDRRYSLERKADQLG-SYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLL--- 842 + L+ + + S + E IQ+ EL + + V+ +++ Sbjct: 652 NEKTTNQKLQNEIQNISISQININSTKIPETQIQDKELQIQQLKKQFEETVLNQKIAYEQ 711 Query: 843 EIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRD 902 E++ NK+++ Q L+EE N + ++Q N + N D E + Q+ + Sbjct: 712 EVQKMNKQVEILEQSLIEEKTNSKKLEYEIQ---NISCQYGNNND---EEIQNLKKQVEE 765 Query: 903 LESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIE---SAIRDKKVLNEKYE-KNIEYVT 958 L + +I ++ L Q + + L E N + S I++ K LNE KN E V Sbjct: 766 LHNQNLKINQQNMEL-TQTQLAMAQLANENNPNTDNLLSEIQNLKNLNETLNLKNEELVQ 824 Query: 959 QLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQ--YINEINKLNA 1016 E ++QE + +E+ + ++ +++ +K+ + + Y N+I +LN Sbjct: 825 AKEKEIQERTEEYRMIIQKMEQESFSVIQHVEERGEKEVRNQANNMDSILYENQIEELNE 884 Query: 1017 LLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQ 1076 ++Q +++ + + Q++ V K EN + + S Q L K Sbjct: 885 TIRQLQQQLEVQHVPNSQKQLTESPEVVRIYKKEDNLINIQENFVNQDEEDSSQ-LQQKD 943 Query: 1077 HNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIIS-STIEPMSDDANNVDXXXXXX 1135 +E+ L E Q +E + K E E + + S I S++ + Sbjct: 944 EQQEIISLKEEVVKQREECDKLKEKIEQEYNTNEDLRQNLSKIVTESEEQDTKYKKQISD 1003 Query: 1136 XXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQ 1195 L ++E I E+ L E K L E + + E H++ +Q Sbjct: 1004 IESKLFLHIKE----IAEKKQLIEDLEKSKKALAE--------QVFSYEEKEHNL--HQQ 1049 Query: 1196 INQLKSKLEQLNTENDNLLSTVAELRSSISSA--VDQRGFEIAELWKQHLAQREADFQKT 1253 + + K +L ++ E + AE R S SS+ +++ +I++L K + Q ++++Q Sbjct: 1050 VVEAKEQLAKIQAETKFQIQE-AEKRHSTSSSQILNENEMKISKL-KSEIQQVQSEYQLK 1107 Query: 1254 EHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDK-EEHLRNLQEK 1312 + Q + ++ + ++ + TQE+ I E+ Q ++ K EE + + ++ Sbjct: 1108 IQQSEQQYTTQINQLNSQIQTLTNQTQEKNALIEEKERKIEEQIQVAKKFEERIAEMVKE 1167 Query: 1313 YADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINE 1372 D++ + + + + K L TE ++ KQ + + NE Sbjct: 1168 REDLLKHDKDIELQSKQLKEIMEKEYKHQLDVQISLAKKLETELEASKQKYQSQVDLFNE 1227 Query: 1373 ENAQ---LKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQ 1429 + + L+ + N+ + ++ E +Q++ E+ K E T+ Sbjct: 1228 QVKKCQVLEVQLNENKEKQQQLELQWNNQKKEIEEQNNQVQF---ELKNKLSELEKTIAS 1284 Query: 1430 RNDEFENVRQQLVEYEKRIEDLT---YEKESELAILRLKMHENANHYETMQKESEIERVK 1486 + E ++ L +Y+ ++ + +KE++L + + + ++ + + +E+ E+ + Sbjct: 1285 QTHEEHQLKNDLEKYQNQLAQIAGQLNQKETQLNLFKKENSALSSKIQQIDEENNTEKQE 1344 Query: 1487 LIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDE 1539 L +++ + L ++ + K E V K E L ++EI + N E Sbjct: 1345 LTQKIEKLEAQQAELQQKYDKQVKQY-ERVKKEKEENDLLADEEIHKLKQNYE 1396 Score = 72.9 bits (171), Expect = 7e-11 Identities = 156/764 (20%), Positives = 330/764 (43%), Gaps = 88/764 (11%) Query: 212 EDTKQQMTKMQENFIA----MEAEWKDEKQRLLKDIESK-DVRISSLEEANKLLEAARFE 266 E+ +M K +E+ + +E + K K+ + K+ + + DV+IS ++ LEA++ + Sbjct: 1158 EERIAEMVKEREDLLKHDKDIELQSKQLKEIMEKEYKHQLDVQISLAKKLETELEASKQK 1217 Query: 267 ISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGS---LEIAN-MT 322 + +++++ + ++ + +K EIEE+ + E+ N ++ Sbjct: 1218 YQSQVDLFNEQVKKCQVLEVQLNENKEKQQQLELQWN-NQKKEIEEQNNQVQFELKNKLS 1276 Query: 323 ELTKKIELLEHLNCQIRQTNKELENKLATMG---TESKAVSSPSKKGSPLISRK-----S 374 EL K I H Q++ ++ +N+LA + + + + KK + +S K Sbjct: 1277 ELEKTIASQTHEEHQLKNDLEKYQNQLAQIAGQLNQKETQLNLFKKENSALSSKIQQIDE 1336 Query: 375 GRNTASK---MKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEK 431 NT + K + L Q DK++ + E K E DL+ E + K Sbjct: 1337 ENNTEKQELTQKIEKLEAQQAELQQKYDKQVKQYERVKKEKE----ENDLLADEEIHKLK 1392 Query: 432 DTXXXXXXXXXXGKD-------TLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQ 484 K+ T + +L+++ +H + + + + V + K E Sbjct: 1393 QNYEALLESEKAAKEDVKKEFITKVDELKIQVARH-DTKTRQTEDKHQKQVKTLEKEVES 1451 Query: 485 LKQELNDEIKDVNVKDLIEKLKSAEEQITQLN-----------DEIDAANKNMIKVKSNH 533 LKQ N +I+ +K + E K EE+ QL DE+ N+ I+V + Sbjct: 1452 LKQLNNKKIE--TMKTIQETCKKLEEEKGQLESQYKKKEQKFIDELKEKNEE-IEVLTQQ 1508 Query: 534 KLKLKQMQ-----KTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEE--KGNLQLHLV 586 K K+ ++Q K I KVS+ ++ +L +EL +K +E+E + N Q + Sbjct: 1509 KKKINEIQNELQEKLIAEQKKVSELSENQEKLAKELQQSEEKKISIEKEWIQKNQQT-IA 1567 Query: 587 DYDSGRMIESDV-YKKMI---------EMENLAETRLKAISLLESQKFDLVQELHILQQK 636 +Y+S ++ E D ++K++ +++ L+ +K ++ +L +++ LQ Sbjct: 1568 EYES-KISEKDAEFEKILSSKQGDSSQQIQELSSKNMKQEKEFREKENNLNNKINTLQSS 1626 Query: 637 YDEVEDKLADISQLQSDQVCSEI--KSVHLEEQIDALSASKKELALVIENLKLDKEQLYG 694 E+KL + + ++ ++ +++ K L ++ID AS KE IE + + ++ Sbjct: 1627 VKNHEEKLKSLEE-ENSKLSTQLSEKIAVLNKEIDTHKASIKENQNQIEAFEKEIKEKNQ 1685 Query: 695 TIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGID 754 IK+LE+DK D+ K ++ + ++ +LE+ A K E+ K++ + I Sbjct: 1686 IIKNLESDKSDLEEKTLKQEEKIVLISTQLEQTKASK-KEIEDKLSRK----------IK 1734 Query: 755 AKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYS 814 K E+++ ++ ++ YK I L+ + + D +S + K Q+ S + + + Sbjct: 1735 EKETEQNIISQDYNQKIQVYKQTIEHLQNN-SRQGDINFSQDLKFSQI-SKITDNLSDNN 1792 Query: 815 EYTIQEDELVNR--LAVLMDHDRVVEKQLLEIEH-ENKELQKKNQILLEENQNLQISLSD 871 + Q D+L + LM + + + +KE + L + ++ Sbjct: 1793 SHDEQADKLSGKELSQRLMSGVAALSQSRASVSSIRSKEETRSMYKKLSQMSMATAAMMS 1852 Query: 872 MQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQ 915 +++ Y +L E A D + +T Q D++ L + +H+ Sbjct: 1853 VKRDYVSLKELAKSIDDHDVNNTSNQ---EDIDPRLTKSEIQHK 1893 >UniRef50_A0DZ20 Cluster: Chromosome undetermined scaffold_7, whole genome shotgun sequence; n=2; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_7, whole genome shotgun sequence - Paramecium tetraurelia Length = 1760 Score = 153 bits (371), Expect = 4e-35 Identities = 229/1140 (20%), Positives = 513/1140 (45%), Gaps = 100/1140 (8%) Query: 471 NTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLND-EIDAANKNMIKV 529 N E ++I + Q QL + L EI+ + V LK +E++ QL + +++ N++ I + Sbjct: 116 NNEHQSQIKEYQNQL-ESLQSEIEKLQVS-----LKQSEQKQQQLQEVQLEQNNQHRIDI 169 Query: 530 KSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYD 589 +S + +L++ + T DN + ++ + L + + E+ NL L ++ D Sbjct: 170 ESLIE-RLQKSESTKDNLQQELQKHQNNLELIAKQKKEIESYKIQLSEQNNL-LDIIKSD 227 Query: 590 SGRMIES---DVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLAD 646 + ++++ + K+ + ++ +LK LE Q + ++L +Q + ++ +L+ Sbjct: 228 NKIIVQNLAEQLKKEEQKTKDANNEKLKLEQSLERQLNEKNEQLKKVQNEIHQLNQELS- 286 Query: 647 ISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDI 706 SQ Q +Q IKS L+EQI+ +++ K+L +++ EQ ++ E I Sbjct: 287 -SQEQKNQKI--IKS--LDEQIEKVNSEIKDLKQKSQHINNINEQQTIKLQQQEEIISQI 341 Query: 707 MNKLQNY---IQENMDLTDKLEKMSAEKI---SELLAKINHEEQSKIQTQFGI---DAKI 757 +N+ + ++E +L KL++ ++I S K ++ K + I ++KI Sbjct: 342 INENSQFKGQVEEQQNLVIKLKEQCQKEIEQKSHFDKKYLDLQEEKENAELRINQLESKI 401 Query: 758 QERDLYIENIES----ELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAY 813 E+ + IES ++ +++ I L + + +ED++ S E K + + LQ++ + Sbjct: 402 LEQQNEQKQIESNTFQDIQNFQNTIQSLNQKL--IEDKQNS-EDKIQEFNNLLQQQMQNN 458 Query: 814 SEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQ 873 + Q+D+L +++ L + KQ+ + + +L+K+ Q L NQ + + Sbjct: 459 QLMSKQQDDLKSQIEQLNIQNEDQGKQIYQNSQQILDLEKQIQDLKIINQQSKDQNEQLI 518 Query: 874 QHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFN 933 Q + + KA TQ ++ LK+ ++ + +I Q +K+ L++E Sbjct: 519 QQIDDNISKA--------------TQETGVQEQLKQKLNQSEDIIEQLQKDKSQLQLELE 564 Query: 934 TQIESAIRDKKVLNEKYEKNIEYVT----QLEAQLQEYKNNIENLNMNVEELNKMNLELI 989 E + +K + ++ E +T +++ Q+QE + I NL +++EE ++ +L Sbjct: 565 QLKEGSNLEKVQILQELSNAKEEITSSDEKIKKQIQEKEEMITNLRLDIEEKSQQTSQLQ 624 Query: 990 DK--HVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYE 1047 D+ ++Q + QS + + ++ L + ++ + I L Q + S ++ Sbjct: 625 DESNNIQSKLQQSEQKYSELLKQVEILTLQIHEQQDTIKQLEQ-----------IKSSFQ 673 Query: 1048 SKLAQFTTKLENMEEEMQRVS-KQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNI 1106 ++L +T + ++++VS K ++K ++E+Q L + DQ + L E +L Sbjct: 674 NQLLIWTETINQKMSDLEQVSQKNDSNTKLLSQEIQALTQRSKDQ-ELLSEAQLEMASQN 732 Query: 1107 PKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQ---EEEEFIQERSVLQEQSAK 1163 ++ I + + + +++ L+ + E +E +Q + +Q+ Sbjct: 733 ESSKDKNIEQLQQELKETIASLESNKQKYEAQYIALQEKLSLEYDELLQNKLNIQKLQLS 792 Query: 1164 LNTELQEC-YTKIIQLET---LNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAE 1219 + Q+C T IQ++ L+ + +QE+ N + S +++ N+ + ++E Sbjct: 793 NQYDQQKCEITNEIQIQKQLFLDCQQELQQFKDQEKFN-MNSYQKEIEDLNELIHKQMSE 851 Query: 1220 LRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSS- 1278 + + ++Q ++ EL ++L Q Q + + Q +A ++++ +D +S Sbjct: 852 -KQILIEELEQIQIKLKEL--ENLKQENETLQNSVRIEQEQKNAMIQQFQKEIDIQKSQI 908 Query: 1279 TQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXX 1338 +E+ N +++++ LQ ++QD L N QE+ + Q++I +++++++ Sbjct: 909 IEEQKNNEQSLDKINQLQQQIQD----LINKQEQVNIDLEQMKISLKQVQEKELKLVSDF 964 Query: 1339 XXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDA 1398 +L T+ Q KQ ++Q I + Q+ + N Sbjct: 965 NYQSVLLEETQLNLDTKVQYIKQQEQQYSAEIQQLKDQILGLNNQNLQLEQQILQLQN-- 1022 Query: 1399 EAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESE 1458 V+EL +S+I Q+ TL Q ++FE E +KRI+D + + Sbjct: 1023 -GHVIELEQNSRDVESKINQENQN---TLIQLRNDFETAAMAFQEQKKRIQDENDAFQVQ 1078 Query: 1459 LAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAK 1518 + L +K N + Q + ++ER + EE ++T + E+ ++L++ + Sbjct: 1079 IEELVIK-----NLEQKQQSQEQLERKQ--EEYQQEVTLLKRQRMEQDEMIQSLQKSQVQ 1131 Query: 1519 TNEMQTALENQEIEIVTLNDEITNLQNMVRAS-SSKIQKHVSFASDTK---QGRDEQLDN 1574 E + L+ I + + +E+ ++ + S+ QKH S D Q +QL+N Sbjct: 1132 LKEKENQLDQLNISLSIIQEELYQMEQKYENNLLSQKQKHESQIEDLHRLIQELKQQLNN 1191 Score = 148 bits (358), Expect = 1e-33 Identities = 182/893 (20%), Positives = 389/893 (43%), Gaps = 77/893 (8%) Query: 701 NDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQER 760 N KED+ N +Q +D + K++ E I K +++ +I+ + +Q Sbjct: 24 NQKEDLTNDIQQIENNELDEQPRAHKIAEESI----VKNENDDNQQIKQ---LQENLQHS 76 Query: 761 DLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQE 820 L +EN + KYK+ C+ E+ + + SL+ + D + Q + K Y Sbjct: 77 HLELENY---IQKYKALECQFSEAQTFQQKQIESLQGQFDHQNNEHQSQIKEYQNQLESL 133 Query: 821 DELVNRLAVLMDHDRVVEKQLLEIE-HENKELQKKNQILLEENQNLQISLSDMQQHYNAL 879 + +L V + ++QL E++ +N + + + L+E Q + + ++QQ Sbjct: 134 QSEIEKLQVSLKQSEQKQQQLQEVQLEQNNQHRIDIESLIERLQKSESTKDNLQQELQKH 193 Query: 880 VEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESA 939 + E Y+ QL + ++NL I +IVQ E L+ E + + A Sbjct: 194 QNNLELIAKQKKEIESYKIQLSE-QNNLLDIIKSDNKIIVQNL--AEQLKKE-EQKTKDA 249 Query: 940 IRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNV---EELNKMNLELIDKHVQKQ 996 +K L + E+ + + QL++ +N I LN + E+ N+ ++ +D+ ++K Sbjct: 250 NNEKLKLEQSLERQL---NEKNEQLKKVQNEIHQLNQELSSQEQKNQKIIKSLDEQIEKV 306 Query: 997 QTQSPDYTE--QYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFT 1054 ++ D + Q+IN IN+ + Q+ EEII+ +I N + V + ++ + + Sbjct: 307 NSEIKDLKQKSQHINNINEQQTIKLQQQEEIIS---QIINENSQFKGQVEEQQNLVIKLK 363 Query: 1055 TKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMN----IPKTE 1110 + + E+ K+ LD ++ E ++ + + + +I E + + E N I + Sbjct: 364 EQCQKEIEQKSHFDKKYLDLQEEKENAELRINQLESKILEQQNEQKQIESNTFQDIQNFQ 423 Query: 1111 GMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQ- 1169 I S + + D N+ D ++Q + +++ L+ Q +LN + + Sbjct: 424 NTIQSLNQKLIEDKQNSEDKIQEFNNLLQQ--QMQNNQLMSKQQDDLKSQIEQLNIQNED 481 Query: 1170 ---ECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISS 1226 + Y Q+ L ++ ++NQ+ +Q + ++Q++ +N + + ++ + Sbjct: 482 QGKQIYQNSQQILDLEKQIQDLKIINQQSKDQNEQLIQQID-DNISKATQETGVQEQLKQ 540 Query: 1227 AVDQRGFEIAELWKQ------HLAQRE--ADFQKTE--HELRVQLSAFESKYEQLLDSVQ 1276 ++Q I +L K L Q + ++ +K + EL S E++ +Q Sbjct: 541 KLNQSEDIIEQLQKDKSQLQLELEQLKEGSNLEKVQILQELSNAKEEITSSDEKIKKQIQ 600 Query: 1277 SSTQEETNKIVTMEQVTSLQNKLQDK----EEHLRNLQEKYADVINQIEILRSEIEDEKV 1332 + TN + +E+ + ++LQD+ + L+ ++KY++++ Q+EIL +I +++ Sbjct: 601 EKEEMITNLRLDIEEKSQQTSQLQDESNNIQSKLQQSEQKYSELLKQVEILTLQIHEQQD 660 Query: 1333 AFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXX 1392 T NQ +++ S N+ N +L Sbjct: 661 TIKQLEQIKSSFQNQLLIWTETINQKMSDLEQVS--QKNDSNTKLLSQEIQALTQRSKDQ 718 Query: 1393 XRVNDAEAKVLELTHQLE-LKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDL 1451 +++A+ LE+ Q E KD I Q E T+ + Q + ++++ L Sbjct: 719 ELLSEAQ---LEMASQNESSKDKNIEQLQQELKETIASLESNKQKYEAQYIALQEKL-SL 774 Query: 1452 TYEK--ESELAILRLKMHENANHYETMQKE--SEIERVKLI-----EEL-NVKITESVSL 1501 Y++ +++L I +L++ +N Y+ + E +EI+ K + +EL K E ++ Sbjct: 775 EYDELLQNKLNIQKLQL---SNQYDQQKCEITNEIQIQKQLFLDCQQELQQFKDQEKFNM 831 Query: 1502 N---KQVAELNKALEEEVAKTNEMQTALENQEI---EIVTLNDEITNLQNMVR 1548 N K++ +LN+ + +++++ + LE +I E+ L E LQN VR Sbjct: 832 NSYQKEIEDLNELIHKQMSEKQILIEELEQIQIKLKELENLKQENETLQNSVR 884 Score = 136 bits (329), Expect = 5e-30 Identities = 270/1325 (20%), Positives = 564/1325 (42%), Gaps = 109/1325 (8%) Query: 218 MTKMQENFIAMEAEWKDEKQRLLKDIE---SKDVRISSLEEA--NKLLEAARFEISLEHS 272 + K ++ + + KD+ ++L++ I+ SK + + ++E KL ++ L+ Sbjct: 496 LEKQIQDLKIINQQSKDQNEQLIQQIDDNISKATQETGVQEQLKQKLNQSEDIIEQLQKD 555 Query: 273 KLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIEL-L 331 K +LE L Q + + EE T +EK +I E+ + L + Sbjct: 556 KSQLQLELEQLKEGSNLEKVQIL--QELSNAKEEITSSDEKIKKQIQEKEEMITNLRLDI 613 Query: 332 EHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASK----MKSPWS 387 E + Q Q E N + + + S K+ L + + K +KS + Sbjct: 614 EEKSQQTSQLQDESNNIQSKLQQSEQKYSELLKQVEILTLQIHEQQDTIKQLEQIKSSFQ 673 Query: 388 Q---LSSETLNQ---DTDKKINKNE--IAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXX 439 + +ET+NQ D ++ KN+ L IQ+L + D+E ++SE Sbjct: 674 NQLLIWTETINQKMSDLEQVSQKNDSNTKLLSQEIQALTQRSKDQE-LLSEAQLEMASQN 732 Query: 440 XXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKD-VNV 498 KD I QLQ Q+ E + + + IA +QE+L E ++ +++ +N+ Sbjct: 733 ESS--KDKNIEQLQ---QELKETIASLESNKQKYEAQYIA-LQEKLSLEYDELLQNKLNI 786 Query: 499 KDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIV 558 + L + ++Q ++ +EI + + + +L+Q K + F+ ++ KEI Sbjct: 787 QKL-QLSNQYDQQKCEITNEIQIQKQLFLDCQQ----ELQQF-KDQEKFN-MNSYQKEIE 839 Query: 559 RLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRL--KAI 616 L E +H + L EE +Q+ L + ++ + E++ + + +E + + + Sbjct: 840 DLNELIHKQMSEKQILIEELEQIQIKLKELENLKQ-ENETLQNSVRIEQEQKNAMIQQFQ 898 Query: 617 SLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEE-QIDALSASK 675 ++ QK +++E +Q D++ I L + Q E ++ LE+ +I + Sbjct: 899 KEIDIQKSQIIEEQKNNEQSLDKINQLQQQIQDLINKQ---EQVNIDLEQMKISLKQVQE 955 Query: 676 KELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKIS-- 733 KEL LV + L T +L+ + I + Q Y E L D++ ++ + + Sbjct: 956 KELKLV-SDFNYQSVLLEETQLNLDTKVQYIKQQEQQYSAEIQQLKDQILGLNNQNLQLE 1014 Query: 734 -ELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESEL-SKYKSRICRLEESIAVMEDR 791 ++L N Q +++KI + + +N +L + +++ +E ++D Sbjct: 1015 QQILQLQNGHVIELEQNSRDVESKINQEN---QNTLIQLRNDFETAAMAFQEQKKRIQDE 1071 Query: 792 RYSLERKADQLG-SYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKE 850 + + + ++L L++KQ++ + +++E + +L ++Q +E + + Sbjct: 1072 NDAFQVQIEELVIKNLEQKQQSQEQLERKQEEYQQEVTLL-------KRQRMEQDEMIQS 1124 Query: 851 LQKKNQILLEENQN----LQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESN 906 LQK +Q+ L+E +N L ISLS +Q+ + +K L++ + K+++Q+ DL Sbjct: 1125 LQK-SQVQLKEKENQLDQLNISLSIIQEELYQMEQKYENNLLSQKQ--KHESQIEDLH-- 1179 Query: 907 LKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQE 966 R+ E + + + E ++ N + K++ E E I+ V +L+ Q + Sbjct: 1180 --RLIQELKQQLNNVESEGRMMQNSLNEMEVLDFKCKELKTENEELKIK-VQELQTQPNQ 1236 Query: 967 YKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEII 1026 K ++ N N ++ ++ + KQ+ + + +Q E +LN + EI Sbjct: 1237 QKGEFQSYNHNNNNEESDQIKELNSEILKQKQEHFEIQQQLTQEKEQLNDQIAVLKGEIQ 1296 Query: 1027 ALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDS--KQHN---EEL 1081 + I Q S+ ++K +Q ++ L N +Q S Q + KQ+N +E Sbjct: 1297 EQKKLIIQQQAQIQSLTQQQQAKQSQESSNLINFNPYLQNHSYQQAQTGDKQNNIPQKEY 1356 Query: 1082 QILVREQDDQIKELKETKLTFEMNIPKTEGMIISST-IEPMSDDANNVDXXXXXXXXXXX 1140 QIL ++ +Q +++ +L+ E+ K++ + + +S ++ +++ Sbjct: 1357 QILEKKSKEQ--QIQIQQLSNELAALKSQQEDKAKVQNQKLSRNSTSMETIVEKCAALQQ 1414 Query: 1141 XLKVQE--EEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQ 1198 + Q + E + ++Q+ +L +++ C+ ++ +L ++ + + E Sbjct: 1415 IIDEQSIINSKLNVEIGLFKQQNEQLKEDIKVCHQELKELRIISQDKFR---LESELQQA 1471 Query: 1199 LKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELR 1258 L EQ NT+ND++ +L + ++ E+ L KQ E QK + +L Sbjct: 1472 LALIAEQHNTQNDSI--QFKQLTQELQEKNKKQSEELESLKKQQ-KLIEKQKQKIQEKLN 1528 Query: 1259 VQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVIN 1318 + E K ++LL Q ++ KI+ +E++ LQ++LQD L+ +Y D I Sbjct: 1529 DAIEELE-KLKKLLQISQQEQDQKNTKIIELERL--LQSQLQD----FSILEGQYKDSIK 1581 Query: 1319 QIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLK 1378 EI++ ++++ + D + + Q QMQ I E +AQ Sbjct: 1582 NYEIIKQQLDELNI-------KSMREIDELNKDNQQKEQRIIQMQGDLQNLIKEVHAQKD 1634 Query: 1379 KSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVR 1438 + + + +LE+ + + + I LT +E + Sbjct: 1635 FQARQKQVSSAPLTKKDKIVVESLANRVQELEMLNKTLKDQLSGKIIKLTNELEEKVSYI 1694 Query: 1439 QQLV-EYEKRIEDLT----YEKESELAILRLKMHENANHY--ETMQKESEI-ERVKLI-E 1489 Q L + K +LT EKE I +LK +N TM + ++ E++KL+ Sbjct: 1695 QLLAYHFSKAYPNLTEADIIEKEDVKLIQQLKKKQNIQEIIERTMIENLQLREQIKLLGA 1754 Query: 1490 ELNVK 1494 ELN K Sbjct: 1755 ELNKK 1759 Score = 102 bits (244), Expect = 9e-20 Identities = 142/793 (17%), Positives = 332/793 (41%), Gaps = 65/793 (8%) Query: 834 DRVVEKQLLEI-EHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESE 892 D +VE+Q E++N++ + NQ N QI +++ + A K + ++E Sbjct: 2 DNLVEEQNSTYNEYDNQQTEVINQKEDLTNDIQQIENNELDEQPRA--HKIAEESIVKNE 59 Query: 893 STKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEK 952 + Q Q++ L+ NL+ +H +QK K +E E T + I + + + + Sbjct: 60 NDDNQ-QIKQLQENLQH-SHLELENYIQKYKALECQFSEAQTFQQKQI--ESLQGQFDHQ 115 Query: 953 NIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEIN 1012 N E+ ++Q++EY+N +E+L +E+L +++L+ ++ Q+ Q + Q+ +I Sbjct: 116 NNEH----QSQIKEYQNQLESLQSEIEKL-QVSLKQSEQKQQQLQEVQLEQNNQHRIDIE 170 Query: 1013 KLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLL 1072 L L++ + L Q++ Q + + +++ + ++ + +L + + Sbjct: 171 SLIERLQKSESTKDNLQQELQKHQ-NNLELIAKQKKEIESYKIQLSEQNNLLDIIKS--- 226 Query: 1073 DSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXX 1132 D+K + L +++++ + K+ KL E ++ + ++ E + N + Sbjct: 227 DNKIIVQNLAEQLKKEEQKTKDANNEKLKLEQSLERQ----LNEKNEQLKKVQNEIHQLN 282 Query: 1133 XXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVN 1192 + Q+ ++ I+ L EQ K+N+E+++ K + +N + T Sbjct: 283 QELSS-----QEQKNQKIIKS---LDEQIEKVNSEIKDLKQKSQHINNINEQQTIKLQQQ 334 Query: 1193 QEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQK 1252 +E I+Q+ ++ Q + + + V +L+ ++Q+ + + A+ + Sbjct: 335 EEIISQIINENSQFKGQVEEQQNLVIKLKEQCQKEIEQKSHFDKKYLDLQEEKENAELRI 394 Query: 1253 TEHELRV-----QLSAFESKYEQLLDSVQSSTQEETNKIVTMEQ-----VTSLQNKLQDK 1302 + E ++ + ES Q + + Q++ Q K++ +Q + N LQ + Sbjct: 395 NQLESKILEQQNEQKQIESNTFQDIQNFQNTIQSLNQKLIEDKQNSEDKIQEFNNLLQQQ 454 Query: 1303 EEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQM 1362 ++ + + ++ D+ +QIE L + ED+ DL+ NQ K Sbjct: 455 MQNNQLMSKQQDDLKSQIEQLNIQNEDQGKQIYQNSQQILDLEKQIQ-DLKIINQQSKDQ 513 Query: 1363 QEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHE 1422 EQ I I++ ++ + + ++N +E + +L E+ Q Sbjct: 514 NEQLIQQIDDNISKATQETGVQEQLKQ----KLNQSEDIIEQLQKDKSQLQLELEQLKEG 569 Query: 1423 YTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESE- 1481 + Q E N ++++ +++I+ EKE + LRL + E + +Q ES Sbjct: 570 SNLEKVQILQELSNAKEEITSSDEKIKKQIQEKEEMITNLRLDIEEKSQQTSQLQDESNN 629 Query: 1482 ------------IERVKLIEELNVKITESVSLNKQVAELNKALEEEV--------AKTNE 1521 E +K +E L ++I E KQ+ ++ + + ++ K ++ Sbjct: 630 IQSKLQQSEQKYSELLKQVEILTLQIHEQQDTIKQLEQIKSSFQNQLLIWTETINQKMSD 689 Query: 1522 MQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELL 1581 ++ + + L+ EI L + + + AS + +D+ ++ + +EL Sbjct: 690 LEQVSQKNDSNTKLLSQEIQALTQRSKDQELLSEAQLEMASQNESSKDKNIEQ-LQQELK 748 Query: 1582 DAVPRAELDLAMY 1594 + + E + Y Sbjct: 749 ETIASLESNKQKY 761 Score = 66.5 bits (155), Expect = 6e-09 Identities = 130/668 (19%), Positives = 273/668 (40%), Gaps = 60/668 (8%) Query: 151 IKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXX 210 +++K + L+ K + + + L+ + E+D++I++ K+ Sbjct: 1087 LEQKQQSQEQLERKQEEYQQEVTLLKRQRMEQDEMIQSLQKSQVQLKEKENQLDQLNISL 1146 Query: 211 X---EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEI 267 E+ Q K + N ++ + + + + + L + I+ +++++E ++++ + E+ Sbjct: 1147 SIIQEELYQMEQKYENNLLSQKQKHESQIEDLHRLIQELKQQLNNVESEGRMMQNSLNEM 1206 Query: 268 SLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIE-PSCEEKTEIEEKGSLEIANMTELTK 326 + K + + +Q E S EE ++ N L + Sbjct: 1207 EVLDFKCKELKTENEELKIKVQELQTQPNQQKGEFQSYNHNNNNEESDQIKELNSEILKQ 1266 Query: 327 KIELLEHLNCQIRQTNKELENKLATMGTE----SKAVSSPSKKGSPLISRKSGRNTASKM 382 K E E + Q+ Q ++L +++A + E K + + L ++ + + Sbjct: 1267 KQEHFE-IQQQLTQEKEQLNDQIAVLKGEIQEQKKLIIQQQAQIQSLTQQQQAKQSQESS 1325 Query: 383 K----SPWSQLSSETLNQDTDKKIN--KNEIAKLE-------MVIQSLNKDLVDKEYVIS 429 +P+ Q S Q DK+ N + E LE + IQ L+ +L + Sbjct: 1326 NLINFNPYLQNHSYQQAQTGDKQNNIPQKEYQILEKKSKEQQIQIQQLSNELAALKSQQE 1385 Query: 430 EKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQEL 489 +K I + QQ ++ S+I+ N E + + EQLK+++ Sbjct: 1386 DKAKVQNQKLSRNSTSMETIVEKCAALQQIIDEQSIINSKLNVE-IGLFKQQNEQLKEDI 1444 Query: 490 ---NDEIKDVNVKDLIE-KLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTID 545 + E+K++ + + +L+S +Q L E + I+ K + ++ +K + Sbjct: 1445 KVCHQELKELRIISQDKFRLESELQQALALIAEQHNTQNDSIQFKQLTQELQEKNKKQSE 1504 Query: 546 NFSKVSDSNKEIVRLTEELHH-LSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIE 604 + K I + +++ L+ + ELE+ K LQ+ + D K+IE Sbjct: 1505 ELESLKKQQKLIEKQKQKIQEKLNDAIEELEKLKKLLQISQQEQDQKNT-------KIIE 1557 Query: 605 MENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDK-LADISQLQSDQVCSE----- 658 +E L +++L+ S+LE Q D ++ I++Q+ DE+ K + +I +L D E Sbjct: 1558 LERLLQSQLQDFSILEGQYKDSIKNYEIIKQQLDELNIKSMREIDELNKDNQQKEQRIIQ 1617 Query: 659 --------IKSVHL-------EEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDK 703 IK VH ++Q+ + +KK+ +V+E+L ++L K L++ Sbjct: 1618 MQGDLQNLIKEVHAQKDFQARQKQVSSAPLTKKD-KIVVESLANRVQELEMLNKTLKDQL 1676 Query: 704 EDIMNKLQNYIQENMDLTDKLEKMSAEKISELL-AKINHEEQSKIQTQFGIDAKIQE--R 760 + KL N ++E + L ++ L A I +E K+ Q IQE Sbjct: 1677 SGKIIKLTNELEEKVSYIQLLAYHFSKAYPNLTEADIIEKEDVKLIQQLKKKQNIQEIIE 1736 Query: 761 DLYIENIE 768 IEN++ Sbjct: 1737 RTMIENLQ 1744 >UniRef50_A0CWC7 Cluster: Chromosome undetermined scaffold_3, whole genome shotgun sequence; n=1; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_3, whole genome shotgun sequence - Paramecium tetraurelia Length = 1425 Score = 153 bits (371), Expect = 4e-35 Identities = 234/1197 (19%), Positives = 513/1197 (42%), Gaps = 93/1197 (7%) Query: 445 KDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKV-QEQLKQELNDEIKDVNVKDLIE 503 K L LQL+ Q+ ++ + GT +D + +V ++L++ + + K+ + KD Sbjct: 208 KQELEQNLQLKQQECLQLQQKL--GTAEDDFRKKQQVILDELQKTIESKTKENSSKD--S 263 Query: 504 KLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNK---EIVRL 560 K++ +E + L+++I + + +V+ + ++ + K + + D +K E+ L Sbjct: 264 KIQDLQENLVLLSEQIKEKDLKIREVQEAEQKEISDIAK--ERIKLIGDLHKCQAELQEL 321 Query: 561 TEELHHLSQKVAELEEEKGNLQ-LHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLL 619 + ++ +L + +Q L ++ D + + + K+ E ++ E I+ L Sbjct: 322 QKTNAQQFSQIQQLTNKATQIQNLSKLEIDKLKQLNQEQQDKLQENQSNIELMNNKINEL 381 Query: 620 ESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVH-LEEQIDALSASKKEL 678 L Q+ L + +++E +L + ++ + +H L+ QI + +L Sbjct: 382 TELNDQLNQQCDQLLKNKEQLEKELVQSKRDVEIELKQNQEFIHELQYQIQNHKNEQLQL 441 Query: 679 ALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAK 738 +N + + Q + +L + + N+ Q I++N L ++ +K + Sbjct: 442 ESKFQNEQFELNQ---QLTNLNEQLQSLTNENQQLIKDNSLLNNEYTGYKKDKDQQ---- 494 Query: 739 INHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERK 798 I+ Q Q +D Q+ +L + IE KY +I L +I +ED++ SL +K Sbjct: 495 IDQLNQLNNQLNNDLDQARQQFNLSQQEIEQ---KYSDQIQNLNSTITQLEDQKQSLLKK 551 Query: 799 ADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQ-LLEIEHENKELQKKNQI 857 A++ LQ+ + + E ++ + + ++ K LL+ + ++L K I Sbjct: 552 ANEEKLQLQKIIATHQQELSLEKDINKQNEIKFTNEISQHKDDLLQKQMLIQQLNDKVHI 611 Query: 858 LLEENQNLQISLSDMQQHYNALVEKANR--TDLAESESTKYQTQLRDLESNLKRITHEHQ 915 L E +++ + ++S Y L+++ N+ T L+E + + + Q + E + K +++ Sbjct: 612 LQEHSKSQETNISKNIDDYKILLDQNNQQITQLSE-QIRQLKKQQKQQEQDSKTTISQYE 670 Query: 916 TLIVQKKKEIEDLEIEFNTQIESAIRDKKV-LNEKYEKNIEYVTQLEAQLQEYKNNIENL 974 + Q +E+ +I+ N ES + K+ L + EK ++Q +Q+ I+ L Sbjct: 671 LQMKQYLQELTQTKIQKN-DAESEKQSKEAQLTQVIEKQKSQLSQANTTIQDLNYQIQQL 729 Query: 975 NMNVEELNKMNLELIDK------HVQKQQTQSPDYTEQYINEI-------NKLNALLKQK 1021 N+++ ++ L ++ + Q T ++Y+NEI ++L LL+++ Sbjct: 730 QQNIKDQDEQRLSIVSSKQSAIYEKEHQITSLDSQVQKYLNEIQSKQEVISELQRLLEKQ 789 Query: 1022 DEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQL-LDSKQHNE- 1079 +E+ +L + Q + V + ++++ ++ ++ M +V + ++ +++N+ Sbjct: 790 KQEVTSLILERERTQKNSSQQVYELQAQIKDLNYEINQLKNSMVQVENEKNINKEEYNQA 849 Query: 1080 --ELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXX 1137 +L+ + Q I EL+E F + + E ++ + S + N + Sbjct: 850 TDQLKEQINRQSTMIAELQE----FLKDSNQKE-LVSTQKATQQSLEINQLQLEFAKLKN 904 Query: 1138 XXXXLKVQEEEEFIQERSV-LQEQSAK----LNTELQECYTKIIQLETLNTELTGHDVVN 1192 L +Q + I++ + Q+Q K N Q KI LE + EL ++ Sbjct: 905 EQTLL-MQNNQSLIEDLQLKYQQQKQKDQDEYNKTSQVNLQKIQNLELESEELKNENLKL 963 Query: 1193 QEQINQLKSKLEQLNTENDNLLSTVAELRSS---ISSAVDQRGFEIAELWKQHLAQREAD 1249 ++QI QL + QL E N + V + S + + ++++ I EL + + Sbjct: 964 KDQIEQLNQTINQLKDEYHNQNNLVQQTNSDQQRLQNEINEKSHRIEELELLN-ENSKTQ 1022 Query: 1250 FQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQV--TSLQNKLQDKEEHLR 1307 + + QL + + + DS Q N+++ Q L+N++ + + + Sbjct: 1023 IDQLNQTMLGQLEMIQFQKNNIQDS-----QIRYNQLLLENQEIQAKLENQILKENSYFK 1077 Query: 1308 NLQEKYADVINQIEILRSEIEDE--KVAFXXXXXXXXXXXXXXXXDLRTEN-QSYKQMQE 1364 ++E Q+E + DE K+ L TE YK+ E Sbjct: 1078 QIEELKVS-FEQLEQANLQQNDEIQKLQNQLEIENKKRENVEQEYKLVTEEFNDYKEQAE 1136 Query: 1365 QSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSE--------- 1415 +SI + K S + ++ + K+ +L+ QL+ + S+ Sbjct: 1137 KSINELQNTLISCKNESKQHINNTLLQQKQKSELDQKLAKLSQQLQSERSQFEFDLHQIQ 1196 Query: 1416 --IYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESEL-AILRLKMHENANH 1472 QK + + + Q+ +E + +QQL + EK +ED+ +E L ++K + Sbjct: 1197 ENFNQKNKDLQLLINQKIEEIQKQQQQLKKQEK-LEDMIFELTIYLKKNQKIKFKRTKSL 1255 Query: 1473 YETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNE----MQTALE- 1527 +T++K+ EI +L + N K+ + KQ++ N+ ++ K E Q LE Sbjct: 1256 NQTLEKQLEINSSQLAQFQNEKLKLQTEI-KQLSNQNQQYLNQIQKYQEYIQQQQKDLEK 1314 Query: 1528 NQEI-EIVTLNDEITN-LQNMVRASSSKIQKHVSFASD-TKQGRDEQLDNTMNKELL 1581 NQ I + LND L+ + K+ + ++F D ++ L T+N++L+ Sbjct: 1315 NQFINKTAVLNDNQGQILEKELTNLQKKLVQKLNFYKDLLSDKKNTDLKQTVNEDLI 1371 Score = 133 bits (321), Expect = 4e-29 Identities = 179/895 (20%), Positives = 378/895 (42%), Gaps = 65/895 (7%) Query: 699 LENDKEDIMNKLQNYIQENMDLTDKL---EKMSAEKISELLAKINHEEQSKIQTQFGIDA 755 +E K+++ LQ QE + L KL E +K +L ++ +SK + D+ Sbjct: 204 IEARKQELEQNLQLKQQECLQLQQKLGTAEDDFRKKQQVILDELQKTIESKTKENSSKDS 263 Query: 756 KIQERDLYIENIESELSKYKSRICRLEES----IAVMEDRRYSLERKADQLGSYLQEKQK 811 KIQ+ + + ++ + +I ++E+ I+ + R L + + LQE QK Sbjct: 264 KIQDLQENLVLLSEQIKEKDLKIREVQEAEQKEISDIAKERIKLIGDLHKCQAELQELQK 323 Query: 812 AYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSD 871 ++ Q +L N+ + + ++ +L ++ E ++ ++NQ +E N L++ Sbjct: 324 TNAQQFSQIQQLTNKATQIQNLSKLEIDKLKQLNQEQQDKLQENQSNIELMNNKINELTE 383 Query: 872 MQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKR---ITHEHQTLIVQKKKEIEDL 928 + N ++ + + E Q++ RD+E LK+ HE Q I K E L Sbjct: 384 LNDQLNQQCDQLLKNK-EQLEKELVQSK-RDVEIELKQNQEFIHELQYQIQNHKNEQLQL 441 Query: 929 EIEFNTQIESAIRDKKVLNEKYE----KNIEYVTQLEAQLQEYKNNIENLNMNVEELNKM 984 E +F + + LNE+ + +N + + EY ++ + +++LN++ Sbjct: 442 ESKFQNEQFELNQQLTNLNEQLQSLTNENQQLIKDNSLLNNEYTGYKKDKDQQIDQLNQL 501 Query: 985 NLEL---IDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMS 1041 N +L +D+ Q+ + ++Y ++I LN+ + Q +++ +L +K N ++ Sbjct: 502 NNQLNNDLDQARQQFNLSQQEIEQKYSDQIQNLNSTITQLEDQKQSLLKKANEEKLQLQK 561 Query: 1042 MVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLT 1101 +++ ++ +L+ K N + E+ + + ++ K + Q+L+++ +D++ L+E + Sbjct: 562 IIATHQQELS--LEKDINKQNEI-KFTNEISQHKDDLLQKQMLIQQLNDKVHILQEHSKS 618 Query: 1102 FEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQS 1161 E NI K + + D N LK Q++++ ++ + + Sbjct: 619 QETNISKN-----IDDYKILLDQNNQ---QITQLSEQIRQLKKQQKQQEQDSKTTISQYE 670 Query: 1162 AKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELR 1221 ++ LQE IQ +E + + I + KS+L Q NT +L + +L+ Sbjct: 671 LQMKQYLQELTQTKIQKNDAESEKQSKEAQLTQVIEKQKSQLSQANTTIQDLNYQIQQLQ 730 Query: 1222 SSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYE---QLLDSVQSS 1278 +I +QR I + + ++E + +++ L+ +SK E +L ++ Sbjct: 731 QNIKDQDEQR-LSIVSSKQSAIYEKEHQITSLDSQVQKYLNEIQSKQEVISELQRLLEKQ 789 Query: 1279 TQEETNKIVTME--------QVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDE 1330 QE T+ I+ E QV LQ +++D + L+ V N+ I + E Sbjct: 790 KQEVTSLILERERTQKNSSQQVYELQAQIKDLNYEINQLKNSMVQVENEKNINKEEYNQA 849 Query: 1331 KVAFXXXXXXXXXXXXXXXXDLRTENQS---YKQMQEQSILNINEENAQLKKSSXXXXXX 1387 L+ NQ Q Q L IN+ + K Sbjct: 850 TDQLKEQINRQSTMIAELQEFLKDSNQKELVSTQKATQQSLEINQLQLEFAKLKNEQTLL 909 Query: 1388 XXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRND-EFENVRQQLVEYEK 1446 + D + K Q + KD + Y KT + + Q + E E ++ + ++ + Sbjct: 910 MQNNQSLIEDLQLKY----QQQKQKDQDEYNKTSQVNLQKIQNLELESEELKNENLKLKD 965 Query: 1447 RIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVK-LIEELNVKITESVSLNK-- 1503 +IE L I +LK + + Q S+ +R++ I E + +I E LN+ Sbjct: 966 QIEQLNQ------TINQLKDEYHNQNNLVQQTNSDQQRLQNEINEKSHRIEELELLNENS 1019 Query: 1504 --QVAELNKALEEEVAKTNEMQTALENQEI---EIVTLNDEI-TNLQNMVRASSS 1552 Q+ +LN+ + ++ + +++ +I +++ N EI L+N + +S Sbjct: 1020 KTQIDQLNQTMLGQLEMIQFQKNNIQDSQIRYNQLLLENQEIQAKLENQILKENS 1074 Score = 128 bits (310), Expect = 9e-28 Identities = 198/956 (20%), Positives = 424/956 (44%), Gaps = 96/956 (10%) Query: 181 EKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLL 240 +KDQ I+ N+ ++ +Q+ + +N + + +D+KQ LL Sbjct: 490 DKDQQIDQLNQLNNQLNNDLDQARQQFNLSQQEIEQKYSDQIQNLNSTITQLEDQKQSLL 549 Query: 241 KDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSI 300 K + +++ K++ + E+SLE K + + L KQ + Sbjct: 550 KKANEEKLQL------QKIIATHQQELSLE--KDINKQNEIKFTNEISQHKDDLLQKQML 601 Query: 301 EPSCEEKTEIEEKGSLEIANMTELTKKIE----LLEHLNCQIRQTN---KELENKLATMG 353 +K I ++ S + T ++K I+ LL+ N QI Q + ++L+ + Sbjct: 602 IQQLNDKVHILQEHSK--SQETNISKNIDDYKILLDQNNQQITQLSEQIRQLKKQQKQQE 659 Query: 354 TESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSET-LNQDTDKKINKNEIAKLEM 412 +SK S + ++ + K + + S E L Q +K+ K+++++ Sbjct: 660 QDSKTTISQYELQMKQYLQELTQTKIQKNDAESEKQSKEAQLTQVIEKQ--KSQLSQANT 717 Query: 413 VIQSLNKDLVDKEYVISEKD----TXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHV 468 IQ LN + + I ++D + K+ I L + Q+++ + Sbjct: 718 TIQDLNYQIQQLQQNIKDQDEQRLSIVSSKQSAIYEKEHQITSLDSQVQKYLN-----EI 772 Query: 469 GTNTEDVNEIAKVQEQLKQELNDEI--KDVNVKDLIEKLKSAEEQITQLNDEIDAANKNM 526 + E ++E+ ++ E+ KQE+ I ++ K+ +++ + QI LN EI+ +M Sbjct: 773 QSKQEVISELQRLLEKQKQEVTSLILERERTQKNSSQQVYELQAQIKDLNYEINQLKNSM 832 Query: 527 IKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEE-EKGNLQLHL 585 ++V++ + ++ + D +L E+++ S +AEL+E K + Q L Sbjct: 833 VQVENEKNINKEEYNQATD-------------QLKEQINRQSTMIAELQEFLKDSNQKEL 879 Query: 586 VDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHI-LQQKYDEVEDKL 644 V ++ + +E L + +LL L+++L + QQ+ + +D+ Sbjct: 880 VSTQKATQQSLEINQLQLEFAKLKNEQ----TLLMQNNQSLIEDLQLKYQQQKQKDQDEY 935 Query: 645 ADISQLQSDQVCS-EIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDK 703 SQ+ ++ + E++S L+ + L ++L I LK + ++ +D+ Sbjct: 936 NKTSQVNLQKIQNLELESEELKNENLKLKDQIEQLNQTINQLKDEYHNQNNLVQQTNSDQ 995 Query: 704 EDIMNKL--QNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERD 761 + + N++ +++ E ++L ++ K +++++ + + E + Q D++I+ Sbjct: 996 QRLQNEINEKSHRIEELELLNENSKTQIDQLNQTM--LGQLEMIQFQKNNIQDSQIRYNQ 1053 Query: 762 LYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQED 821 L +EN E + +K +++I + +E+ + S E+ E QK ++ I+ Sbjct: 1054 LLLENQEIQ-AKLENQILKENSYFKQIEELKVSFEQLEQANLQQNDEIQKLQNQLEIENK 1112 Query: 822 ELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISL-SDMQQHY-NAL 879 + N VE++ + E + +++ + + E QN IS ++ +QH N L Sbjct: 1113 KREN-----------VEQEYKLVTEEFNDYKEQAEKSINELQNTLISCKNESKQHINNTL 1161 Query: 880 VEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESA 939 +++ +++L + + K QL+ S + H+ Q QK K DL++ N +IE Sbjct: 1162 LQQKQKSEL-DQKLAKLSQQLQSERSQFEFDLHQIQENFNQKNK---DLQLLINQKIEEI 1217 Query: 940 IRDKKVL--NEKYEKNIEYVTQLEAQLQEYK-NNIENLNMNVE---ELNKMNLELIDKHV 993 + ++ L EK E I +T + Q+ K ++LN +E E+N L Sbjct: 1218 QKQQQQLKKQEKLEDMIFELTIYLKKNQKIKFKRTKSLNQTLEKQLEINSSQLAQFQNEK 1277 Query: 994 QKQQT---QSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKL 1050 K QT Q + +QY+N+I K ++Q+ ++ + NQ IN V ++D + ++ Sbjct: 1278 LKLQTEIKQLSNQNQQYLNQIQKYQEYIQQQQKD-LEKNQFINKTAV-----LNDNQGQI 1331 Query: 1051 AQFTTKLENMEEEM-QRVS--KQLLDSKQHNEELQILVREQDDQIKELKETKLTFE 1103 + +L N+++++ Q+++ K LL K+ N +L+ V E D I K+ + FE Sbjct: 1332 LE--KELTNLQKKLVQKLNFYKDLLSDKK-NTDLKQTVNE--DLITIKKDYIIAFE 1382 Score = 109 bits (263), Expect = 5e-22 Identities = 168/924 (18%), Positives = 400/924 (43%), Gaps = 68/924 (7%) Query: 702 DKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERD 761 +KE++ N+++ +I + K K+ + K++ R Sbjct: 134 EKEELKNQIEYFIHIKQKVESKNSKVXXXXXXXXXXXXXXXXDFADDSPR--QGKLKARI 191 Query: 762 LYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGS--------YLQEKQKAY 813 EN E + ++R LE+++ + + L++K L E QK Sbjct: 192 QRYENDEKQYIHIEARKQELEQNLQLKQQECLQLQQKLGTAEDDFRKKQQVILDELQKTI 251 Query: 814 SEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISL-SDM 872 T + +++ L ++ ++ +Q+ E + + +E+Q+ Q + + +I L D+ Sbjct: 252 ESKTKENSSKDSKIQDLQENLVLLSEQIKEKDLKIREVQEAEQKEISDIAKERIKLIGDL 311 Query: 873 QQHYNAL--VEKANRTDLAE-SESTKYQTQLRDLE----SNLKRITHEHQTLIVQKKKEI 925 + L ++K N ++ + T TQ+++L LK++ E Q + + + I Sbjct: 312 HKCQAELQELQKTNAQQFSQIQQLTNKATQIQNLSKLEIDKLKQLNQEQQDKLQENQSNI 371 Query: 926 EDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIE-NLNMNVEELNKM 984 E + + N E + D+ LN++ ++ ++ QLE +L + K ++E L N E ++++ Sbjct: 372 ELMNNKINELTE--LNDQ--LNQQCDQLLKNKEQLEKELVQSKRDVEIELKQNQEFIHEL 427 Query: 985 NLELIDKHVQKQQTQSPDYTEQY-----INEINKLNALLKQKDEEIIALNQKINNAQVSY 1039 ++ + ++ Q +S EQ+ + +N+ L +++++I N +NN Y Sbjct: 428 QYQIQNHKNEQLQLESKFQNEQFELNQQLTNLNEQLQSLTNENQQLIKDNSLLNNEYTGY 487 Query: 1040 MSMVSDYESKLAQFTTKLEN-MEEEMQR--VSKQLLDSKQHNEELQILVREQDDQIKELK 1096 +L Q +L N +++ Q+ +S+Q ++ K +++++Q L Q+++ K Sbjct: 488 KKDKDQQIDQLNQLNNQLNNDLDQARQQFNLSQQEIEQK-YSDQIQNL-NSTITQLEDQK 545 Query: 1097 ETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSV 1156 ++ L + N K + I +T + +++ Q +++ +Q++ + Sbjct: 546 QSLLK-KANEEKLQLQKIIATHQQELSLEKDINKQNEIKFTNEIS---QHKDDLLQKQML 601 Query: 1157 LQEQSAKLNTELQECYTKIIQLETLNTELTGHDVV---NQEQINQLKSKLEQLNTENDNL 1213 +Q+ + K++ LQE ++K Q ++ + + ++ N +QI QL ++ QL + Sbjct: 602 IQQLNDKVHI-LQE-HSK-SQETNISKNIDDYKILLDQNNQQITQLSEQIRQLKKQQK-- 656 Query: 1214 LSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLD 1273 + +++IS Q + EL + + + +A+ +K E QL+ K + L Sbjct: 657 -QQEQDSKTTISQYELQMKQYLQELTQTKIQKNDAESEKQSKE--AQLTQVIEKQKSQLS 713 Query: 1274 SVQSSTQEETNKIVTMEQ------------VTSLQNKLQDKEEHLRNLQEKYADVINQIE 1321 ++ Q+ +I ++Q V+S Q+ + +KE + +L + +N+I+ Sbjct: 714 QANTTIQDLNYQIQQLQQNIKDQDEQRLSIVSSKQSAIYEKEHQITSLDSQVQKYLNEIQ 773 Query: 1322 ILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSS 1381 + I + + + +Q ++Q Q I ++N E QLK S Sbjct: 774 SKQEVISELQRLLEKQKQEVTSLILERERTQKNSSQQVYELQAQ-IKDLNYEINQLKNSM 832 Query: 1382 XXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQ---KTHEYTITLTQR-NDEFENV 1437 N A ++ E ++ +E+ + +++ + TQ+ + + Sbjct: 833 VQVENEKNINKEEYNQATDQLKEQINRQSTMIAELQEFLKDSNQKELVSTQKATQQSLEI 892 Query: 1438 RQQLVEYEKRIEDLTYEKESELAILR-LKMHENANHYETMQKESEIERVKLIEELNVKIT 1496 Q +E+ K + T ++ +++ L++ + + ++ +V L + N+++ Sbjct: 893 NQLQLEFAKLKNEQTLLMQNNQSLIEDLQLKYQQQKQKDQDEYNKTSQVNLQKIQNLEL- 951 Query: 1497 ESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQK 1556 ES L + +L +E+ N+++ NQ + N + LQN + S +I++ Sbjct: 952 ESEELKNENLKLKDQIEQLNQTINQLKDEYHNQNNLVQQTNSDQQRLQNEINEKSHRIEE 1011 Query: 1557 HVSFASDTKQGRDEQLDNTMNKEL 1580 + ++ + + +QL+ TM +L Sbjct: 1012 -LELLNENSKTQIDQLNQTMLGQL 1034 Score = 105 bits (251), Expect = 1e-20 Identities = 154/782 (19%), Positives = 337/782 (43%), Gaps = 56/782 (7%) Query: 838 EKQLLEIEHENKE----LQKKNQILLEENQNLQISLSDMQQHYNALVEKANRT-DLAESE 892 EKQ + IE +E LQ K Q L+ Q L + D ++ ++++ +T + E Sbjct: 198 EKQYIHIEARKQELEQNLQLKQQECLQLQQKLGTAEDDFRKKQQVILDELQKTIESKTKE 257 Query: 893 STKYQTQLRDLESNLKRITHE--HQTLIVQ-----KKKEIEDLEIEFNTQIESAIRDKKV 945 ++ ++++DL+ NL ++ + + L ++ ++KEI D+ E I + + Sbjct: 258 NSSKDSKIQDLQENLVLLSEQIKEKDLKIREVQEAEQKEISDIAKERIKLIGDLHKCQAE 317 Query: 946 LNEKYEKNIEYVTQLEAQLQEYKNNIENLN-MNVEELNKMNLELIDKHVQKQQTQSPDYT 1004 L E + N + +Q++ QL I+NL+ + +++L ++N E DK +Q+ Q+ + + Sbjct: 318 LQELQKTNAQQFSQIQ-QLTNKATQIQNLSKLEIDKLKQLNQEQQDK-LQENQS-NIELM 374 Query: 1005 EQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEM 1064 INE+ +LN L Q+ ++++ +++ V D E +L Q + ++ ++ Sbjct: 375 NNKINELTELNDQLNQQCDQLLKNKEQLEKELV---QSKRDVEIELKQNQEFIHELQYQI 431 Query: 1065 Q-RVSKQL-LDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMS 1122 Q ++QL L+SK NE+ ++ +Q + E ++ + K ++ + Sbjct: 432 QNHKNEQLQLESKFQNEQFEL--NQQLTNLNEQLQSLTNENQQLIKDNSLLNNEYTGYKK 489 Query: 1123 DDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLN 1182 D +D L Q ++F + QE K + ++Q + I QLE Sbjct: 490 DKDQQIDQLNQLNNQLNNDLD-QARQQFNLSQ---QEIEQKYSDQIQNLNSTITQLEDQK 545 Query: 1183 TELTGHDVVNQEQINQ-LKSKLEQLNTENDNLLSTVAELRSSISSAVD---QRGFEIAEL 1238 L + Q+ + + + ++L+ E D + + IS D Q+ I +L Sbjct: 546 QSLLKKANEEKLQLQKIIATHQQELSLEKDINKQNEIKFTNEISQHKDDLLQKQMLIQQL 605 Query: 1239 -WKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQN 1297 K H+ Q + Q+T +S Y+ LLD + + +I +++ Q Sbjct: 606 NDKVHILQEHSKSQET------NISKNIDDYKILLDQNNQQITQLSEQIRQLKKQQKQQE 659 Query: 1298 KLQDKEEHLRNLQEK-YADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTEN 1356 + LQ K Y + Q +I +++ E EK + T Sbjct: 660 QDSKTTISQYELQMKQYLQELTQTKIQKNDAESEKQSKEAQLTQVIEKQKSQLSQANTTI 719 Query: 1357 QSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKD--- 1413 Q +Q NI +++ Q ++ +++V + ++++ K Sbjct: 720 QDLNYQIQQLQQNIKDQDEQRLSIVSSKQSAIYEKEHQITSLDSQVQKYLNEIQSKQEVI 779 Query: 1414 SEIY----QKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYE-KESELAILRLKMHE 1468 SE+ ++ E T + +R +N QQ+ E + +I+DL YE + + ++++++ + Sbjct: 780 SELQRLLEKQKQEVTSLILERERTQKNSSQQVYELQAQIKDLNYEINQLKNSMVQVENEK 839 Query: 1469 NANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALEN 1528 N N E Q +++ E++N + T L + + + N+ +E V+ Q +LE Sbjct: 840 NINKEEYNQATDQLK-----EQINRQSTMIAELQEFLKDSNQ--KELVSTQKATQQSLEI 892 Query: 1529 QEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAE 1588 ++++ ++ N Q ++ ++ + + + ++ +D+ N ++ L + E Sbjct: 893 NQLQLEFA--KLKNEQTLLMQNNQSLIEDLQLKYQQQKQKDQDEYNKTSQVNLQKIQNLE 950 Query: 1589 LD 1590 L+ Sbjct: 951 LE 952 >UniRef50_A0DR95 Cluster: Chromosome undetermined scaffold_60, whole genome shotgun sequence; n=1; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_60, whole genome shotgun sequence - Paramecium tetraurelia Length = 1119 Score = 153 bits (370), Expect = 5e-35 Identities = 241/1105 (21%), Positives = 486/1105 (43%), Gaps = 94/1105 (8%) Query: 502 IEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLT 561 +E+L+S +Q+ Q D+ + NKN V ++K +Q +D ++ + + Sbjct: 15 VERLQSLTKQLNQDIDQANLQNKNSQAVIDQQSTEIKLLQTKLDCINRDQLELQNKYQSL 74 Query: 562 EELH-HLSQKVAELEEEKGNLQ--LHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISL 618 E+ H H++ V ++ + L+ LVD R I+ D +++++ + L + KA Sbjct: 75 EQQHLHVTDLVNQITAGQITLEQLKDLVDELKNRSIQYDEIQELLQGQALHDVISKAEQF 134 Query: 619 LESQKFDLVQELHILQQKYDEVEDKL-ADISQLQSDQVCSEIKSVHLEEQIDALSASKKE 677 + + ++ QEL ++Y E+ KL D+ + + D + ++ +LE+ I L+ Sbjct: 135 --TLQCNINQELRDQLEQYPEIVIKLNQDLDKYKQDIINNKSSIANLEQTIADLNQEIHI 192 Query: 678 LALVIENLKLDKEQLYGTIK-DLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKI--SE 734 L ++E + I+ LE ++ KL Q+N +L D++E+++ K+ Sbjct: 193 LKQLLEQEQNKNSLNQSQIQLQLETQLNELRLKLSQTEQKNEELEDEVEQINFFKVQMES 252 Query: 735 LLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYS 794 L +I E + + + + + + +++ +L+ S+ L + I +ED+ Sbjct: 253 QLQEILKENNKIMVDKDKLASDNLSLNTHNDDLSDQLNLQTSQNQDLNKKILELEDQVRL 312 Query: 795 LERKAD-----QLGSYLQEKQ-KAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHEN 848 L+ + ++ Q+ Q ++Y+E +D + L + ++ +Q L ++++ Sbjct: 313 LKNQLSEDNDLEIQIIRQDAQLQSYNERLQMQDNEIQDLNLNNAEQKLNYQQSLN-KYQD 371 Query: 849 KELQKKNQILLEENQNLQISLSD-MQQHYNALVEKANRTDLAESESTKYQTQLRDLESNL 907 +QK ++I +E Q QI L D + + N + ++ + E + + Q + + Sbjct: 372 ILIQKDHKI--QELQQTQIDLQDQISELQNQIANLRHQAQIDADEINQLKLQHQQFQGK- 428 Query: 908 KRITHEHQTLIVQKKKEIEDLEIEF-NTQIESAIRDKKVLNEKYEKNIEYVTQ-LEAQLQ 965 T+I+ + +I+ ++E N ++ + + +LN+K +++ Q LE Q Q Sbjct: 429 ---NDSSNTIIINFQNQIQQFKLEIQNHLLQISELESSILNQKQ----QFINQKLELQ-Q 480 Query: 966 EYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEI 1025 Y+ IE L +E NK + D+ +Q + Q + Q +E +L ++ +KD+E+ Sbjct: 481 HYQQIIEKL----QEENKSLQDQNDQQIQSLEEQG-NQILQLSSENQELQQIIDEKDQEL 535 Query: 1026 IALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILV 1085 LN + Q Y S E+ L + +L + Q+ K L + L++ V Sbjct: 536 DKLNLYVRKQQEIYESNTKKNEA-LEESNRELLFKQNSFQKTIKDLYTQL---DALKLEV 591 Query: 1086 REQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQ 1145 E+D +LK+ +L+ E I K ++ T + N+ L +Q Sbjct: 592 NEKD----QLKQQRLSLEYEISK-----LNQTNADLLQQITNMKIEINNYQIQITNLNLQ 642 Query: 1146 EEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQ 1205 + I+ RS QE ++ N +L+E +TKI Q ET+ + N++QIN+ + +++Q Sbjct: 643 IDNTEIELRSSYQENNSSEN-QLKELFTKIEQQETIINQ-------NEKQINEDEFRIQQ 694 Query: 1206 LNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFE 1265 L D L A+ + +Q F I +L + L++ D +K E+EL ++ F Sbjct: 695 L---LDELQKLNAKNKEYYKKFEEQEIF-IKQL-QAELSESSNDIKKLENELLLKEEEFN 749 Query: 1266 SKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRS 1325 LD + E N + + + ++ ++ + NL+ +Y V+ +E L+ Sbjct: 750 E-----LDDDYNKIWNELNAVKNNQSNLDSNARSEELQQLVANLKSEYDLVLKDLEALKK 804 Query: 1326 EIED------EKVAFXXXXXXXXXXXXXXXXDLRTE---NQSYKQMQEQSILNINEENAQ 1376 ++ D +K L+ E NQ + Q+Q I E++ Q Sbjct: 805 QLIDKDSQLNQKAMLVDKFNVKVMNQTSELRSLKQEIENNQIVIENQQQRIAK-QEQHIQ 863 Query: 1377 LKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFEN 1436 S + N ++V+EL QL + S++ E T L Q+ E Sbjct: 864 DLLRSLESEKKSQQSQVKDNTDNSRVMEL-QQLNMNLSKVID---EKTQKLYQQEQEILI 919 Query: 1437 VRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVK-LIEELNVKI 1495 + ++L E E I + E +L LRLK T QK S I + + +E K Sbjct: 920 LNEKLRETENYIRGI----EFQLNELRLKYESQVQ--ITYQKSSIISTSEDITDEFQSKF 973 Query: 1496 TESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQ 1555 + L ++ +L + + ++ TN + LE E +I L+ EI+ +N + S+ +I Sbjct: 974 QQ---LQQKYIQLQR--DYQILLTN--SSKLEEYENKIALLSLEISRYRNSSKKSTPQIN 1026 Query: 1556 KHVSFASDTKQGRDEQLDNTMNKEL 1580 + S ++ T + +L + +EL Sbjct: 1027 RESSSSAKTSKFNLGELQSPYPEEL 1051 Score = 124 bits (300), Expect = 2e-26 Identities = 192/949 (20%), Positives = 416/949 (43%), Gaps = 107/949 (11%) Query: 394 LNQDTDKKI-----NKNEIAKLEMVIQSLNKDL-VDKEYVISEKDTXXXXXXXXXXGKDT 447 LNQD DK NK+ IA LE I LN+++ + K+ + E++ +T Sbjct: 158 LNQDLDKYKQDIINNKSSIANLEQTIADLNQEIHILKQLLEQEQNKNSLNQSQIQLQLET 217 Query: 448 LIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKS 507 + +L+L+ Q + + ++V +I + Q++ +L + +K+ N K +++K K Sbjct: 218 QLNELRLKLSQTEQKNEELE-----DEVEQINFFKVQMESQLQEILKENN-KIMVDKDKL 271 Query: 508 AEEQITQLNDEIDAANKNMIKVKSNHKLKLK------QMQKTIDNFSKVSDSNKEIVRLT 561 A + ++ D +++ ++ N L K Q++ + S+ +D +I+R Sbjct: 272 ASDNLSLNTHNDDLSDQLNLQTSQNQDLNKKILELEDQVRLLKNQLSEDNDLEIQIIRQD 331 Query: 562 EELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLES 621 +L ++++ + E +L L+ + +K+ ++L + + I + + Sbjct: 332 AQLQSYNERLQMQDNEIQDLNLNNAE------------QKLNYQQSL--NKYQDILIQKD 377 Query: 622 QKFDLVQELHI-LQQKYDEVEDKLADI---SQLQSDQVCSEIKSVHLEEQIDALSASKKE 677 K +Q+ I LQ + E+++++A++ +Q+ +D++ +++K H +Q + S Sbjct: 378 HKIQELQQTQIDLQDQISELQNQIANLRHQAQIDADEI-NQLKLQH--QQFQGKNDSSNT 434 Query: 678 LALVIEN-LKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELL 736 + + +N ++ K ++ + + + I+N+ Q +I + ++L +++ EK+ E Sbjct: 435 IIINFQNQIQQFKLEIQNHLLQISELESSILNQKQQFINQKLELQQHYQQI-IEKLQEEN 493 Query: 737 AKINHEEQSKIQTQ-------FGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVME 789 + + +IQ+ + ++ QE I+ + EL K + + +E Sbjct: 494 KSLQDQNDQQIQSLEEQGNQILQLSSENQELQQIIDEKDQELDKLNLYVRKQQEIYESNT 553 Query: 790 DRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENK 849 + +LE +L QK + Q D L +L V + D++ ++Q L +E+E Sbjct: 554 KKNEALEESNRELLFKQNSFQKTIKDLYTQLDAL--KLEV-NEKDQL-KQQRLSLEYEIS 609 Query: 850 ELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDL----AESESTKYQTQLRDLES 905 +L + N LL++ N++I +++ Q L + + T++ + E+ + QL++L + Sbjct: 610 KLNQTNADLLQQITNMKIEINNYQIQITNLNLQIDNTEIELRSSYQENNSSENQLKELFT 669 Query: 906 NLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIE----YVTQLE 961 ++ + +T+I Q +K+I + E Q+ ++ N++Y K E ++ QL+ Sbjct: 670 KIE----QQETIINQNEKQINEDEFRIQ-QLLDELQKLNAKNKEYYKKFEEQEIFIKQLQ 724 Query: 962 AQLQEYKNNIENLN----MNVEELN----------------KMNLELIDKHVQKQQTQS- 1000 A+L E N+I+ L + EE N K N +D + + ++ Q Sbjct: 725 AELSESSNDIKKLENELLLKEEEFNELDDDYNKIWNELNAVKNNQSNLDSNARSEELQQL 784 Query: 1001 -PDYTEQYINEINKLNALLKQKDEEIIALNQK---INNAQVSYMSMVSDYESKLAQFTTK 1056 + +Y + L AL KQ ++ LNQK ++ V M+ S+ S + Sbjct: 785 VANLKSEYDLVLKDLEALKKQLIDKDSQLNQKAMLVDKFNVKVMNQTSELRSLKQEIENN 844 Query: 1057 LENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISS 1116 +E + QR++KQ + L+ + Q Q+K+ + E+ + M +S Sbjct: 845 QIVIENQQQRIAKQEQHIQDLLRSLESEKKSQQSQVKDNTDNSRVMEL---QQLNMNLSK 901 Query: 1117 TIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQE-RSVLQEQSAKLNTELQECYTKI 1175 I+ + + K++E E +I+ L E K +++Q Y K Sbjct: 902 VIDEKTQKLYQQEQEILILNE-----KLRETENYIRGIEFQLNELRLKYESQVQITYQKS 956 Query: 1176 IQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEI 1235 + T + ++T Q + QL+ K QL + LL+ ++L + + EI Sbjct: 957 SIIST-SEDITDE---FQSKFQQLQQKYIQLQRDYQILLTNSSKL-EEYENKIALLSLEI 1011 Query: 1236 AEL---WKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQE 1281 + K+ Q + + + L +S Y + L + QS+T + Sbjct: 1012 SRYRNSSKKSTPQINRESSSSAKTSKFNLGELQSPYPEELKTEQSNTSQ 1060 Score = 54.4 bits (125), Expect = 2e-05 Identities = 131/670 (19%), Positives = 278/670 (41%), Gaps = 68/670 (10%) Query: 160 VLQVKMKIME--TTILDLQEKI-NEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQ 216 + Q K++I I +L+ I N+K Q I K + + Q Sbjct: 443 IQQFKLEIQNHLLQISELESSILNQKQQFINQKLELQQHYQQIIEKLQEENKSLQDQNDQ 502 Query: 217 QMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQ 276 Q+ ++E + + E Q L + I+ KD + L L + EI ++K + Sbjct: 503 QIQSLEEQGNQI-LQLSSENQELQQIIDEKDQELDKLN----LYVRKQQEIYESNTKKNE 557 Query: 277 ELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNC 336 LE+ K K E+ EK L+ ++ LE+ Sbjct: 558 ALEESNRELLFKQNSFQKTIKDLYTQLDALKLEVNEKDQLKQQRLS--------LEYEIS 609 Query: 337 QIRQTNKELENKLATMGTE---------SKAVSSPSKKGSPLISRKSGRNTASKMKSPWS 387 ++ QTN +L ++ M E + + + + S + ++ +++K ++ Sbjct: 610 KLNQTNADLLQQITNMKIEINNYQIQITNLNLQIDNTEIELRSSYQENNSSENQLKELFT 669 Query: 388 QL-SSETLNQDTDKKINKNEIAKLEMVIQSLNK-DLVDKEYV--ISEKDTXXXXXXXXXX 443 ++ ET+ +K+IN++E +++ ++ L K + +KEY E++ Sbjct: 670 KIEQQETIINQNEKQINEDEF-RIQQLLDELQKLNAKNKEYYKKFEEQEIFIKQLQAELS 728 Query: 444 GKDTLIAQLQ----LEHQQHME--------GPSLIHVGTNTEDVNEIAKVQE--QLKQEL 489 I +L+ L+ ++ E L V N +++ A+ +E QL L Sbjct: 729 ESSNDIKKLENELLLKEEEFNELDDDYNKIWNELNAVKNNQSNLDSNARSEELQQLVANL 788 Query: 490 NDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSK 549 E D+ +KDL K ++ +QLN + +K +KV N +L+ +++ I+N Sbjct: 789 KSEY-DLVLKDLEALKKQLIDKDSQLNQKAMLVDKFNVKV-MNQTSELRSLKQEIENNQI 846 Query: 550 VSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLA 609 V ++ ++ R+ ++ H+ + LE EK + Q + D +++E++ L Sbjct: 847 VIENQQQ--RIAKQEQHIQDLLRSLESEKKSQQSQVKDNTDN--------SRVMELQQLN 896 Query: 610 ETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKS-VHLEEQI 668 K I + + QE+ IL +K E E+ + I + Q +++ + +S V + Q Sbjct: 897 MNLSKVIDEKTQKLYQQEQEILILNEKLRETENYIRGI-EFQLNELRLKYESQVQITYQK 955 Query: 669 DALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIM---NKLQNYIQENMDLTDKLE 725 ++ ++ ++ + + + +QL L+ D + ++ +KL+ Y + L+ ++ Sbjct: 956 SSIISTSED---ITDEFQSKFQQLQQKYIQLQRDYQILLTNSSKLEEYENKIALLSLEIS 1012 Query: 726 KMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESI 785 + + +IN E S +T ++Q Y E +++E S S+I S Sbjct: 1013 RY-RNSSKKSTPQINRESSSSAKTSKFNLGELQSP--YPEELKTEQSN-TSQIFIQPFSN 1068 Query: 786 AVMEDRRYSL 795 +++++Y L Sbjct: 1069 PKVDEQQYGL 1078 Score = 50.4 bits (115), Expect = 4e-04 Identities = 39/195 (20%), Positives = 92/195 (47%), Gaps = 6/195 (3%) Query: 1395 VNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYE 1454 ++D +K + T Q + + E+ + +Y + + N + + +Q ++ + I +L Sbjct: 124 LHDVISKAEQFTLQCNI-NQELRDQLEQYPEIVIKLNQDLDKYKQDIINNKSSIANL--- 179 Query: 1455 KESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEE 1514 E +A L ++H E Q ++ + + ++ +L ++ E Q + N+ LE+ Sbjct: 180 -EQTIADLNQEIHILKQLLEQEQNKNSLNQSQIQLQLETQLNELRLKLSQTEQKNEELED 238 Query: 1515 EVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDN 1574 EV + N + +E+Q EI+ N++I ++ + + + + H SD + Q + Sbjct: 239 EVEQINFFKVQMESQLQEILKENNKIMVDKDKLASDNLSLNTHNDDLSDQLNLQTSQ-NQ 297 Query: 1575 TMNKELLDAVPRAEL 1589 +NK++L+ + L Sbjct: 298 DLNKKILELEDQVRL 312 >UniRef50_Q6C359 Cluster: Similar to DEHA0C09658g Debaryomyces hansenii IPF 1836.1; n=1; Yarrowia lipolytica|Rep: Similar to DEHA0C09658g Debaryomyces hansenii IPF 1836.1 - Yarrowia lipolytica (Candida lipolytica) Length = 1906 Score = 153 bits (370), Expect = 5e-35 Identities = 234/1259 (18%), Positives = 491/1259 (38%), Gaps = 89/1259 (7%) Query: 359 VSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLN 418 + PS IS + ++ +KS +L + K EI L+ + L Sbjct: 699 LKDPSHSAGGKISYELVQSLEDNVKSLTDELEEVSTALSETKSATSAEIKDLKAIRDDLE 758 Query: 419 KDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEI 478 +DL + + + E K + A+ QL+ E S + T D+ + Sbjct: 759 RDLQETDTRLKEARGALESLEGKFHTK--VAAEKQLQTSLEAERKSGSGLQTELADLKKK 816 Query: 479 AKVQEQLKQELNDEIKDVNV-KDLIEK-LKSAEEQITQLNDEIDAANKNMIKVKSNHKLK 536 + Q K +L +++ + KD E + +++ QL E D ++K Sbjct: 817 LQTLTQQKTQLTTQVETLTAAKDKAESGINKMSKELFQLTRERDGSDKEK---------- 866 Query: 537 LKQMQKTIDNFSKVSDSNK-EIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIE 595 K +QK + K S + E+ L L ++ ++ E LQ ++ ++ Sbjct: 867 -KGLQKELAELKKQDSSRRTELTALAANLKQVTAARSDFENRLKGLQS---EHSETETLK 922 Query: 596 SDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQV 655 + +K+ E + LE Q +L LQ YDE++ +S + D Sbjct: 923 DKLIEKLKSAATQLEDHKSRGANLEGQIRELQGSHEALQNSYDELQKSHEQLSSVGKDNE 982 Query: 656 CSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQ 715 + L+ ++ + A + L+ K + +KE + ++ + + Sbjct: 983 SLASELAELKTKLSKIETESSSRADKVSELEKSLSAAEAQSKSVAAEKEKVSGQIATHEE 1042 Query: 716 ENMDLTDKLEKMSAE--KISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSK 773 L ++L + +AE K+ LA + SK + D +I++ +E S+L+ Sbjct: 1043 TIKRLKEELSERTAELDKLKSDLASSEKDLASKTKDVSAKDTEIEKLKSELETANSKLAS 1102 Query: 774 YKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAY----SEYTIQEDELVNRLAV 829 + L + + E K + S L E++ +E + + + A Sbjct: 1103 TAKEVEILTSELKAAKSDACDSETKIKAVESELVEQKSKVEHLNAELAAKSSSVESGAAE 1162 Query: 830 LMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLA 889 L + +VE ++E ++KEL K + L + + L+ S+++ L K+ Sbjct: 1163 LAEKVALVESLTAKLESKDKELATKTEELSAKEKELETKTSELETKTAELTTKSKELTAK 1222 Query: 890 ESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEK 949 E+T Y ++++LE++ + + TL +DL E ++ +A + + N Sbjct: 1223 SDEATTYSAKVKELETSSAALEKKQTTLKAMADNLTKDL-AEKTKELVAAKSELESSNTS 1281 Query: 950 YEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYIN 1009 ++ ++ +T+ + ++ + E + ++ + K S Sbjct: 1282 SKEEVDVLTKKLSDATAEAVELKKSSQAAETEASSKVSALEAKLTKASESSK-------A 1334 Query: 1010 EINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSK 1069 E++K+N LL + +K+ ++ + + VS ++ + T K EN E ++ + Sbjct: 1335 ELDKVNKLLS-------SFKEKLQTSKDDHSTEVSKLTEQVRESTLKAENFEHDISSLKD 1387 Query: 1070 QLLDSKQHNEELQILVREQDDQIKEL--KETKLTFEMNIPKTEGMIISSTIEPMSDDANN 1127 L +++ + L+ E D IKE+ + T LT + + E S ++ D+ Sbjct: 1388 DLAQAEKERDALR---TELDTSIKEMENERTSLTKDADSATKELTNKVSMLQTKLDELTA 1444 Query: 1128 VDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTG 1187 +E + E L+E AK + T I LE +ELT Sbjct: 1445 SHKKALGDSETEAKGLKKEIKAAQAEIKTLEEVKAK----YEASQTDIKGLEKQVSELT- 1499 Query: 1188 HDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQRE 1247 E + S+ E + T + L + +S + + V + E+A+ +H + Sbjct: 1500 ------ESLETKTSETEAVKTALEEKLEEASSAKSKLETKVTELEKEVADNQGKH-GKAA 1552 Query: 1248 ADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQE-ETNKIVTMEQVTSLQNKLQDKEEHL 1306 ++ + + L+ ++S ++ ++L S +++ + + + M +VT L+ +L D ++ L Sbjct: 1553 SELEASVKTLKSEISTHKATIDELKKSAETAAADTSSERTELMSKVTELETQLADAKKEL 1612 Query: 1307 RNLQEKYAD--------------VINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDL 1352 N++ +AD + ++ +++E E DL Sbjct: 1613 DNVKSTHADGSKKQASELNELKTKLEEVATANTKLETELKNASAKLEEEQAAKTKLSSDL 1672 Query: 1353 RTENQ---SYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQL 1409 + + ++ + S +EE A LK + + K+ +L +L Sbjct: 1673 EAKTKVSADFETELKASQTQHDEEVASLKMEIKSLRDEQTSNASSAGEFKGKIEKLEVEL 1732 Query: 1410 ELKDSEIYQKT---HEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKES---ELAILR 1463 + K++E+ K + L + E ++ +L ++ T E ES EL + Sbjct: 1733 KTKETELQTKASNLESASSALEAASKELKSKATELESASSELKSKTSELESKTTELKTIN 1792 Query: 1464 LKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQ 1523 ++ + + +T K +E+E K E V T+S + K +AEL ++ +E+ KTN+ + Sbjct: 1793 TELKDRTSELKT--KTTELES-KSTELKTVSDTQSAT-EKALAEL-QSKYDELLKTNKAK 1847 Query: 1524 TALENQEI---EIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKE 1579 +A + E L IT+L V K+++H SD D+ D+ + E Sbjct: 1848 SAATKDMVPKSEYEELMLMITDLDEKVEKYKEKLEEHGVEISDDDDDDDDDDDDDEDDE 1906 Score = 118 bits (283), Expect = 2e-24 Identities = 217/1079 (20%), Positives = 457/1079 (42%), Gaps = 97/1079 (8%) Query: 215 KQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISL--EHS 272 + ++T + N + A D + RL K ++S+ +L++ KL+E + + +H Sbjct: 884 RTELTALAANLKQVTAARSDFENRL-KGLQSEHSETETLKD--KLIEKLKSAATQLEDHK 940 Query: 273 KLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLE 332 LE + ++ S E+ + + + + + EL K+ +E Sbjct: 941 SRGANLEGQIRELQGSHEALQN-SYDELQKSHEQLSSVGKDNESLASELAELKTKLSKIE 999 Query: 333 HLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSE 392 + ELE L+ +SK+V++ +K S I+ + T ++K S+ ++E Sbjct: 1000 TESSSRADKVSELEKSLSAAEAQSKSVAAEKEKVSGQIA--THEETIKRLKEELSERTAE 1057 Query: 393 TLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVI----SEKDTXXXXXXXXXXGKDTL 448 DK K+++A E + S KD+ K+ I SE +T + L Sbjct: 1058 -----LDKL--KSDLASSEKDLASKTKDVSAKDTEIEKLKSELETANSKLASTAKEVEIL 1110 Query: 449 IAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSA 508 ++L+ + + I +E V + +KV E L EL K +V+ +L Sbjct: 1111 TSELKAAKSDACDSETKIK-AVESELVEQKSKV-EHLNAEL--AAKSSSVESGAAELAEK 1166 Query: 509 EEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQ-KTIDNFSKVSD---SNKEIVRLTEEL 564 + L ++++ +K + K K+++ KT + +K ++ +KE+ ++E Sbjct: 1167 VALVESLTAKLESKDKELATKTEELSAKEKELETKTSELETKTAELTTKSKELTAKSDEA 1226 Query: 565 HHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKF 624 S KV ELE L+ + + ++ K + E + + A S LES Sbjct: 1227 TTYSAKVKELETSSAALEKKQTTL---KAMADNLTKDLAEK---TKELVAAKSELESSNT 1280 Query: 625 DLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIEN 684 +E+ +L +K + D A+ +L+ +E ++ ++ AL A K A Sbjct: 1281 SSKEEVDVLTKK---LSDATAEAVELKKSSQAAETEA---SSKVSALEA-KLTKASESSK 1333 Query: 685 LKLDK-EQLYGTIKD-LENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHE 742 +LDK +L + K+ L+ K+D ++ ++ + T K E + IS L + Sbjct: 1334 AELDKVNKLLSSFKEKLQTSKDDHSTEVSKLTEQVRESTLKAENFEHD-ISSLKDDLAQA 1392 Query: 743 EQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQL 802 E+ + + +D I+E +EN + L+K + + + ++ L+ K D+L Sbjct: 1393 EKERDALRTELDTSIKE----MENERTSLTK------DADSATKELTNKVSMLQTKLDEL 1442 Query: 803 GSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEEN 862 + +KA + + L + + +E+ + E +++ + + E Sbjct: 1443 TA---SHKKALGDSETEAKGLKKEIKAAQAEIKTLEEVKAKYEASQTDIKGLEKQVSELT 1499 Query: 863 QNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKK 922 ++L+ S+ + AL EK A S +K +T++ +LE + +H Sbjct: 1500 ESLETKTSETEAVKTALEEKLEE---ASSAKSKLETKVTELEKEVADNQGKH-------G 1549 Query: 923 KEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELN 982 K +LE T ++S I K ++ +K+ E + + L V EL Sbjct: 1550 KAASELEASVKT-LKSEISTHKATIDELKKS------AETAAADTSSERTELMSKVTEL- 1601 Query: 983 KMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSM 1042 + L K + ++ D +++ +E+N+ LK K EE+ N K+ + + Sbjct: 1602 ETQLADAKKELDNVKSTHADGSKKQASELNE----LKTKLEEVATANTKLETELKNASAK 1657 Query: 1043 VSDYESKLAQFTTKLENMEEEMQRVSKQLLDSK-QHNEELQILVREQDDQIKELKETKLT 1101 + + ++ + ++ LE + +L S+ QH+EE+ L E IK L++ + + Sbjct: 1658 LEEEQAAKTKLSSDLEAKTKVSADFETELKASQTQHDEEVASLKME----IKSLRDEQTS 1713 Query: 1102 FEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQS 1161 + + +G I +E + + L+ +E + + L+ S Sbjct: 1714 NASSAGEFKGKIEKLEVE-LKTKETELQTKASNLESASSALEA-ASKELKSKATELESAS 1771 Query: 1162 AKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELR 1221 ++L ++ E +K +L+T+NTEL +++ ++LK+K +L +++ L TV++ + Sbjct: 1772 SELKSKTSELESKTTELKTINTEL-------KDRTSELKTKTTELESKSTE-LKTVSDTQ 1823 Query: 1222 SSISSAVDQRGFEIAELWKQHLAQREAD---FQKTEH-ELRVQLSAFESKYEQLLDSVQ 1276 S+ A+ + + EL K + A+ A K+E+ EL + ++ + K E+ + ++ Sbjct: 1824 SATEKALAELQSKYDELLKTNKAKSAATKDMVPKSEYEELMLMITDLDEKVEKYKEKLE 1882 Score = 50.8 bits (116), Expect = 3e-04 Identities = 76/426 (17%), Positives = 168/426 (39%), Gaps = 17/426 (3%) Query: 1168 LQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSA 1227 ++E +T++ + + + ++ E + L+ ++ L E + + + ++E +S+ S+ Sbjct: 687 VKENFTRLSRALLKDPSHSAGGKISYELVQSLEDNVKSLTDELEEVSTALSETKSATSA- 745 Query: 1228 VDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIV 1287 EI +L K E D Q+T+ L+ A ES + V + Q +T+ Sbjct: 746 ------EIKDL-KAIRDDLERDLQETDTRLKEARGALESLEGKFHTKVAAEKQLQTSLEA 798 Query: 1288 TMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXX 1347 + + LQ +L D ++ L+ L ++ + Q+E L + + + Sbjct: 799 ERKSGSGLQTELADLKKKLQTLTQQKTQLTTQVETLTAAKDKAESGINKMSKELFQLTRE 858 Query: 1348 XXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTH 1407 + + K++ E L + + + + ++ + K L+ H Sbjct: 859 RDGSDKEKKGLQKELAE---LKKQDSSRRTELTALAANLKQVTAARSDFENRLKGLQSEH 915 Query: 1408 -QLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKM 1466 + E ++ +K L N+ Q+ E + E L + EL K Sbjct: 916 SETETLKDKLIEKLKSAATQLEDHKSRGANLEGQIRELQGSHEALQNSYD-ELQ----KS 970 Query: 1467 HENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTAL 1526 HE + + E +L +L+ TES S +V+EL K+L A++ + Sbjct: 971 HEQLSSVGKDNESLASELAELKTKLSKIETESSSRADKVSELEKSLSAAEAQSKSVAAEK 1030 Query: 1527 ENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPR 1586 E +I T + I L+ + ++++ K S + +++ + + K+ + Sbjct: 1031 EKVSGQIATHEETIKRLKEELSERTAELDKLKSDLASSEKDLASKTKDVSAKDTEIEKLK 1090 Query: 1587 AELDLA 1592 +EL+ A Sbjct: 1091 SELETA 1096 >UniRef50_UPI0000F2140F Cluster: PREDICTED: similar to nuclear mitotic apparatus protein 1,, partial; n=2; Danio rerio|Rep: PREDICTED: similar to nuclear mitotic apparatus protein 1,, partial - Danio rerio Length = 1886 Score = 152 bits (369), Expect = 7e-35 Identities = 294/1422 (20%), Positives = 585/1422 (41%), Gaps = 147/1422 (10%) Query: 233 KDEKQR-LLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXX 291 KDE+ R L K+ ES D + ++E N + A EH + ++L+Q Sbjct: 320 KDEEIRNLTKEYESVDNELKLVKEQNVEINAMIKSNRKEHEETVEKLQQELHCAASAASE 379 Query: 292 XXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLAT 351 +Q + S E T ++E+ N + +++ +LE + +++ L+N+LA Sbjct: 380 K---QEQMLVLSA-EVTSLKEQICRYSENEAQKQQELSILEAQHNVLKENLTSLQNQLA- 434 Query: 352 MGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLS-SETLNQDTDKKINKNEIAKL 410 +A +S S+K S I + +LS ETL + T +++ K + +L Sbjct: 435 -----EATTSASQKESEFILLQ-------------QELSHQETLREQT-QELEKIKREEL 475 Query: 411 EMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGT 470 E ++ L +++ + SE ++ ++ LQ E + + Sbjct: 476 EGIVSELQAKIIEVSSIASE--------------REACVSSLQYEMKDQLSKAKQCEADL 521 Query: 471 NTEDVNEIAKVQEQLKQELNDEI--KDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIK 528 E ++ +QE L N I K+ +++ L + LK E Q +EI A+ + + Sbjct: 522 RNEMKEKVGNLQE-LLDAANHGIAEKEHHLESLNQSLKQMELLYCQKEEEIIASQQAKEQ 580 Query: 529 VKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDY 588 +++N + + ++ +D + N+EI+R E HLS +V+ L+EE Q D Sbjct: 581 LENN----IAEQKQQLDEIQQ----NREILR--NERDHLSTRVSSLQEEIHCSQQEFSDL 630 Query: 589 DSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADIS 648 + + + +K++ ++N E + S ES+ L QEL Q+ E +L I Sbjct: 631 QTDHNV---LKEKLVNLQNQLEQAMITASQKESELLLLQQELS-HQETLREKALELEAIK 686 Query: 649 QLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMN 708 + + ++ E++ LE + L++ ++ + +EN D++ KD N + Sbjct: 687 REEFEKKVKELQDRILE--VSTLASQREAQVISLENEMRDQQLSANQSKD--NLCREWQE 742 Query: 709 KLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGI-DAKIQERDLYIENI 767 KL ++ +D+ + ++ L K+ E +Q + + + + DL Sbjct: 743 KL-GILKGELDVVSRDAADKDHQLESLDQKLKEMEMVVLQKEKDVMETHQAKEDLEKRIA 801 Query: 768 ESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRL 827 E E K K I R E E SL+ + +KQ+ S ++ + L + Sbjct: 802 ELEECKQKLEIMRNERDHLSTEVA--SLKEEIHSYQDTQMQKQQTISVLEVENNALKENM 859 Query: 828 AVLMDHDRVVEKQLLEIEHENKELQKK---NQILLEENQNLQISL-SDMQQHYNALVEKA 883 A L ++ + +++ +N ELQ K + L E+ Q L+I + ++ L K Sbjct: 860 AAL---EKQLAEEITTASQKNSELQNKLHQQESLHEKAQELEIGRHEEFERRVRELQAKV 916 Query: 884 NR--TDLAESESTKYQTQLRDLESNLK-RITHEHQTLIVQKKKEIEDLEIEFNTQIESAI 940 T +E E+ Y Q +L +LK +++ + ++++K E EIE ++ Sbjct: 917 QEVSTLASEKEAVAYSLQ-EELTGHLKAKVSEDDLRRVLEEKVETLQREIE-TASCDATS 974 Query: 941 RD--KKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELID--KH---V 993 +D + L++K + Q E + E +N+ E+L + EL N EL +H V Sbjct: 975 KDGLLQTLDQKLRQMEMLCQQKEDAVFEIQNSKEDLQKEMNELVSKNQELEGCLQHLEMV 1034 Query: 994 QKQQTQSPDYTEQYINEINKLNALLKQKDEEII-ALNQKINNAQVSYMSM---VSDYESK 1049 +K++ + +IN + KQ + ++ +KI Q S VS+ E Sbjct: 1035 KKEKDLLSNEVTSLKEQINDQSLRAKQSEADLCKVFEEKIETLQGQLESSSRDVSEKEKH 1094 Query: 1050 LAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKT 1109 L K+ M+ Q+ +L+ + E+LQ + E + ++L+ EM K+ Sbjct: 1095 LQTLHQKVSQMDLLCQQKENAVLEMQNAKEDLQKKIDELVSEKQQLEGCLQNLEM--VKS 1152 Query: 1110 EGMIISSTIEPMSDDANNVDXXXXXXXXXXXXL----------KVQEEEEFIQERSVLQE 1159 E ++S+ + + D N+ D + +++ + E+ L + Sbjct: 1153 ERDLLSTEVTSIKDQLNDQDLKAKQSEDDLRKVLEEKIKNLQGQLETASRDVSEKDQLLQ 1212 Query: 1160 QSAKLNTELQECYTK-------IIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDN 1212 + T++ + Y K ++Q++ + G +V ++Q+ + LE ++ DN Sbjct: 1213 TLDQKVTQMDQLYKKKEKYALDLLQVKENLEKRIGEIIVEKQQLEGCQQNLETVSKAKDN 1272 Query: 1213 LLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHE-LRVQLSAFESKYEQL 1271 LL+ + L+ I S ++ E+ +H E + EH L+ L + + +L Sbjct: 1273 LLNELTSLKVEIQS------YQEKEVQMKH----ELSVLENEHNILQENLDTLQKQVVEL 1322 Query: 1272 LDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVIN-------QIEILR 1324 S E N++ E+ LQ K Q E+ +LQ K ++ QI L+ Sbjct: 1323 TVSASQKESELQNEVCKQEK---LQEKAQKLEKDAGDLQAKILEISTLASEREAQISSLK 1379 Query: 1325 SEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYK---QMQEQSILNINEENAQLKKSS 1381 EI + + +L+ + + + ++Q + +N++ Q+++ Sbjct: 1380 DEINSQHLKAKQSEDDLLRVFEEKIENLQGQLEIARLDVSDKDQLLQTLNQKLKQMEELC 1439 Query: 1382 XXXXXXXXXXXXRVNDAEAKVLEL---THQLELKDSEIYQKTHEYTITLTQR-NDEFENV 1437 D E K++EL Q ++ E+ ++ ++ +L Q E E Sbjct: 1440 KQKETCVLEMHQTKEDLEKKIVELQADKSQQNQQNLEMLRQEKDHLKSLNQTIRRECEAS 1499 Query: 1438 RQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQ----KESEIERVKL-IEELN 1492 R+ E E +E+ T S LA+ + + E ++ K +E K +E+ Sbjct: 1500 RKIRAELELNVEEQT---ASILALKKASQQWEEQNQELLEQLKAKTEAVEHYKAQVEKAM 1556 Query: 1493 VKITESVSLNKQVAELNKALEE--EVAK--TNEMQTALENQEIEIVTLNDEITNLQNMVR 1548 L + ELNK LE+ EV+K ++T L +E+ ND+ +L V+ Sbjct: 1557 NHYNGKKQLLLEAQELNKTLEQSLEVSKREAKALETELTLARMELNQANDKEKSLAAKVK 1616 Query: 1549 ASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELD 1590 +++ + ++ D+ D + L VP + D Sbjct: 1617 TLEAQVDFADRQLREKRRIADDGEDLRQKENLYFRVPEKQQD 1658 Score = 144 bits (350), Expect = 1e-32 Identities = 280/1465 (19%), Positives = 619/1465 (42%), Gaps = 146/1465 (9%) Query: 215 KQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKL 274 +Q++ K+ + + EWK+ K+ L K++ L E +L+ +IS+ L Sbjct: 15 EQEVAKLTVVHESAQTEWKNRKELLEKELNEAVTHKECLSEQVLILQG---KISV----L 67 Query: 275 AQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEH- 333 EL++ ++SI ++K E+E + E + + T +++L+ Sbjct: 68 EDELKKAQSQERGEVLGPIMELQESISHLEKKKAEVEALLAEERCSFEKETARLQLVVFD 127 Query: 334 LNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSET 393 L I E E + T+ + +S+ + R R +++ S Sbjct: 128 LEKSINSIRLERETLQEALKTQKEMLSAQISA----LERDVSRLQQVEVQLTAEIKISAD 183 Query: 394 LNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYV-ISEKDTXXXXXXXXXXGKDTLIA-Q 451 L Q ++ K +A L+ ++ SL+ ++ E S++D + T+ + Sbjct: 184 LRQQREELEGK--VASLDRMVHSLHAEIQGLEVERASQQDAINSLISDLQIARATVQEYE 241 Query: 452 LQLEHQQHM--EGPSLIHVG-TNTEDVNEIAKVQEQLKQELND----EIKDVN-VKDLIE 503 +LE Q + E SL + T +++N K L+ E+N+ + ++ N V + + Sbjct: 242 KKLEEHQKVVAENNSLKNEACTMQQELNNHLKAIGDLQAEVNELRFEKTEEENKVSEALV 301 Query: 504 KLKSAEEQITQLNDEI---DAANKNMIKVKSNHKLKLKQM-QKTIDNFSKVSDSNKE--- 556 K++S + +I L ++I D +N+ K + +LK + ++ ++ + + + KE Sbjct: 302 KIESLQTEILHLCEKISLKDEEIRNLTKEYESVDNELKLVKEQNVEINAMIKSNRKEHEE 361 Query: 557 -IVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKA 615 + +L +ELH + +E +E+ L + ++ + + EN A+ + + Sbjct: 362 TVEKLQQELHCAASAASEKQEQMLVLSAEVTS------LKEQICRYS---ENEAQKQ-QE 411 Query: 616 ISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVH---LEEQIDALS 672 +S+LE+Q L + L LQ +++ + SQ +S+ + + + H L EQ L Sbjct: 412 LSILEAQHNVLKENLTSLQ---NQLAEATTSASQKESEFILLQQELSHQETLREQTQELE 468 Query: 673 ASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKI 732 K+E +E + + + + + +++E ++ LQ E D K ++ A+ Sbjct: 469 KIKRE---ELEGIVSELQAKIIEVSSIASEREACVSSLQ---YEMKDQLSKAKQCEADLR 522 Query: 733 SELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRR 792 +E+ K+ + ++ GI E++ ++E++ L + + C+ EE I + + Sbjct: 523 NEMKEKVGNLQELLDAANHGI----AEKEHHLESLNQSLKQMELLYCQKEEEIIASQQAK 578 Query: 793 YSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQ 852 LE + L E Q+ + D L R++ L + +++ +++ ++ L+ Sbjct: 579 EQLENNIAEQKQQLDEIQQNREILRNERDHLSTRVSSLQEEIHCSQQEFSDLQTDHNVLK 638 Query: 853 KKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRD-LESNLKRIT 911 +K L + + I+ S + L ++ + + ++ + + R+ E +K + Sbjct: 639 EKLVNLQNQLEQAMITASQKESELLLLQQELSHQETLREKALELEAIKREEFEKKVKELQ 698 Query: 912 H---EHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVT-QLEAQLQEY 967 E TL Q++ ++ LE E Q SA + K L ++++ + + +L+ ++ Sbjct: 699 DRILEVSTLASQREAQVISLENEMRDQQLSANQSKDNLCREWQEKLGILKGELDVVSRDA 758 Query: 968 KNNIENLNMNVEELNKMNLELIDKHVQKQQT-QSPDYTEQYINEIN----KLNALLKQKD 1022 + L ++L +M + ++ K +T Q+ + E+ I E+ KL + ++D Sbjct: 759 ADKDHQLESLDQKLKEMEMVVLQKEKDVMETHQAKEDLEKRIAELEECKQKLEIMRNERD 818 Query: 1023 E---EIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNE 1079 E+ +L ++I++ Q + M + ENM +++++++ + Q N Sbjct: 819 HLSTEVASLKEEIHSYQDTQMQKQQTISVLEVENNALKENMAALEKQLAEEITTASQKNS 878 Query: 1080 ELQILVREQDDQIKELKETKL----TFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXX 1135 ELQ + +Q+ ++ +E ++ FE + + + + + ++ + V Sbjct: 879 ELQNKLHQQESLHEKAQELEIGRHEEFERRVRELQAKV--QEVSTLASEKEAVAYSLQEE 936 Query: 1136 XXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQ----ECYTKIIQLETLNTELTGHDVV 1191 KV E++ R VL+E+ L E++ + +K L+TL+ +L +++ Sbjct: 937 LTGHLKAKVSEDDL----RRVLEEKVETLQREIETASCDATSKDGLLQTLDQKLRQMEML 992 Query: 1192 NQEQ---INQLKSKLEQLNTENDNLLSTVAELRSS------ISSAVDQRGFEIAELWKQH 1242 Q++ + ++++ E L E + L+S EL + D E+ L K+ Sbjct: 993 CQQKEDAVFEIQNSKEDLQKEMNELVSKNQELEGCLQHLEMVKKEKDLLSNEVTSL-KEQ 1051 Query: 1243 LAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNK---IVTMEQVTSLQNKL 1299 + + +++E +L FE K E L ++SS+++ + K + T+ Q S + L Sbjct: 1052 INDQSLRAKQSEADL---CKVFEEKIETLQGQLESSSRDVSEKEKHLQTLHQKVSQMDLL 1108 Query: 1300 -QDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQS 1358 Q KE + +Q D+ +I+ L SE + + L TE S Sbjct: 1109 CQQKENAVLEMQNAKEDLQKKIDELVSEKQQLEGCLQNLEMVKSERDL-----LSTEVTS 1163 Query: 1359 YKQMQEQSILNINEENAQLKK---SSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSE 1415 K L + L+K R + ++L+ Q + + Sbjct: 1164 IKDQLNDQDLKAKQSEDDLRKVLEEKIKNLQGQLETASRDVSEKDQLLQTLDQKVTQMDQ 1223 Query: 1416 IYQKTHEYTITLTQRNDEFEN-------VRQQLVEYEKRIEDLTYEKES---ELAILRLK 1465 +Y+K +Y + L Q + E +QQL ++ +E ++ K++ EL L+++ Sbjct: 1224 LYKKKEKYALDLLQVKENLEKRIGEIIVEKQQLEGCQQNLETVSKAKDNLLNELTSLKVE 1283 Query: 1466 M-----------HENA---NHYETMQKESEIERVKLIE----------ELNVKITESVSL 1501 + HE + N + +Q+ + + +++E EL ++ + L Sbjct: 1284 IQSYQEKEVQMKHELSVLENEHNILQENLDTLQKQVVELTVSASQKESELQNEVCKQEKL 1343 Query: 1502 NKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFA 1561 ++ +L K + AK E+ T +E +I +L DEI + + S + + Sbjct: 1344 QEKAQKLEKDAGDLQAKILEISTLASEREAQISSLKDEINSQHLKAKQSEDDLLRVFEEK 1403 Query: 1562 SDTKQGRDE--QLDNTMNKELLDAV 1584 + QG+ E +LD + +LL + Sbjct: 1404 IENLQGQLEIARLDVSDKDQLLQTL 1428 Score = 134 bits (325), Expect = 1e-29 Identities = 267/1430 (18%), Positives = 603/1430 (42%), Gaps = 134/1430 (9%) Query: 212 EDTKQQMTKMQENFIAMEAEWK----DEKQRLLKDIESKDVRISSLEEANKLLEAARFEI 267 E +Q+ +Q +E E K E+ +L I IS LE+ +EA E Sbjct: 51 ECLSEQVLILQGKISVLEDELKKAQSQERGEVLGPIMELQESISHLEKKKAEVEALLAEE 110 Query: 268 SLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEI--EEKGSLE--IANMTE 323 K L Q L +++++ + + + E+ + +LE ++ + + Sbjct: 111 RCSFEKETARL-QLVVFDLEKSINSIRLERETLQEALKTQKEMLSAQISALERDVSRLQQ 169 Query: 324 LTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPL-ISRKSGRNTASKM 382 + ++ ++ +RQ +ELE K+A++ + V S + L + R S ++ + + Sbjct: 170 VEVQLTAEIKISADLRQQREELEGKVASL---DRMVHSLHAEIQGLEVERASQQDAINSL 226 Query: 383 KSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXX 442 S Q++ T+ Q+ +KK+ +++ E N L ++ + ++ Sbjct: 227 ISD-LQIARATV-QEYEKKLEEHQKVVAE------NNSLKNEACTMQQELNNHLKA---- 274 Query: 443 XGKDTLIAQLQLEHQQHMEGPSLIHVGTNTED-VNEIAKVQEQLKQELNDEIKDVNVKDL 501 I LQ E + L T E+ V+E E L+ E+ + +++KD Sbjct: 275 ------IGDLQAEVNE------LRFEKTEEENKVSEALVKIESLQTEILHLCEKISLKD- 321 Query: 502 IEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLT 561 E++++ ++ +++E+ + +++ + K K+ ++T++ +L Sbjct: 322 -EEIRNLTKEYESVDNELKLVKEQNVEINAMIKSNRKEHEETVE-------------KLQ 367 Query: 562 EELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLES 621 +ELH + +E +E+ L + ++ + + EN A+ + + +S+LE+ Sbjct: 368 QELHCAASAASEKQEQMLVLSAEVTS------LKEQICR---YSENEAQ-KQQELSILEA 417 Query: 622 QKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVH---LEEQIDALSASKKEL 678 Q L + L LQ +++ + SQ +S+ + + + H L EQ L K+E Sbjct: 418 QHNVLKENLTSLQ---NQLAEATTSASQKESEFILLQQELSHQETLREQTQELEKIKRE- 473 Query: 679 ALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAK 738 +E + + + + + +++E ++ LQ E D K ++ A+ +E+ K Sbjct: 474 --ELEGIVSELQAKIIEVSSIASEREACVSSLQ---YEMKDQLSKAKQCEADLRNEMKEK 528 Query: 739 INHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERK 798 + + ++ G I E++ ++E++ L + + C+ EE I + + LE Sbjct: 529 VGNLQELLDAANHG----IAEKEHHLESLNQSLKQMELLYCQKEEEIIASQQAKEQLENN 584 Query: 799 ADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQIL 858 + L E Q+ + D L R++ L + +++ +++ ++ L++K L Sbjct: 585 IAEQKQQLDEIQQNREILRNERDHLSTRVSSLQEEIHCSQQEFSDLQTDHNVLKEKLVNL 644 Query: 859 LEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLR-DLESNLKRITH---EH 914 + + I+ S + L ++ + + ++ + + R + E +K + E Sbjct: 645 QNQLEQAMITASQKESELLLLQQELSHQETLREKALELEAIKREEFEKKVKELQDRILEV 704 Query: 915 QTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVT-QLEAQLQEYKNNIEN 973 TL Q++ ++ LE E Q SA + K L ++++ + + +L+ ++ + Sbjct: 705 STLASQREAQVISLENEMRDQQLSANQSKDNLCREWQEKLGILKGELDVVSRDAADKDHQ 764 Query: 974 LNMNVEELNKMNLELIDKHVQKQQT-QSPDYTEQYINEI----NKLNALLKQKDE---EI 1025 L ++L +M + ++ K +T Q+ + E+ I E+ KL + ++D E+ Sbjct: 765 LESLDQKLKEMEMVVLQKEKDVMETHQAKEDLEKRIAELEECKQKLEIMRNERDHLSTEV 824 Query: 1026 IALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILV 1085 +L ++I++ Q + M + ENM +++++++ + Q N ELQ + Sbjct: 825 ASLKEEIHSYQDTQMQKQQTISVLEVENNALKENMAALEKQLAEEITTASQKNSELQNKL 884 Query: 1086 REQDDQIKELKETKL----TFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXX 1141 +Q+ ++ +E ++ FE + + + + + ++ + V Sbjct: 885 HQQESLHEKAQELEIGRHEEFERRVRELQAKV--QEVSTLASEKEAVAYSLQEELTGHLK 942 Query: 1142 LKVQEEEEFIQERSVLQEQSAKLNTELQ----ECYTKIIQLETLNTELTGHDVVNQEQ-- 1195 KV E++ R VL+E+ L E++ + +K L+TL+ +L +++ Q++ Sbjct: 943 AKVSEDD----LRRVLEEKVETLQREIETASCDATSKDGLLQTLDQKLRQMEMLCQQKED 998 Query: 1196 -INQLKSKLEQLNTENDNLLSTVAELR------SSISSAVDQRGFEIAELWKQHLAQREA 1248 + ++++ E L E + L+S EL + D E+ L K+ + + Sbjct: 999 AVFEIQNSKEDLQKEMNELVSKNQELEGCLQHLEMVKKEKDLLSNEVTSL-KEQINDQSL 1057 Query: 1249 DFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNK---IVTMEQVTSLQNKL-QDKEE 1304 +++E +L FE K E L ++SS+++ + K + T+ Q S + L Q KE Sbjct: 1058 RAKQSEADL---CKVFEEKIETLQGQLESSSRDVSEKEKHLQTLHQKVSQMDLLCQQKEN 1114 Query: 1305 HLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQE 1364 + +Q D+ +I+ L SE + + L TE S K Sbjct: 1115 AVLEMQNAKEDLQKKIDELVSEKQQLEGCLQNLEMVKSERDL-----LSTEVTSIKDQLN 1169 Query: 1365 QSILNINEENAQLKK---SSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTH 1421 L + L+K R + ++L+ Q + ++Y+K Sbjct: 1170 DQDLKAKQSEDDLRKVLEEKIKNLQGQLETASRDVSEKDQLLQTLDQKVTQMDQLYKKKE 1229 Query: 1422 EYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESE 1481 +Y + L Q + E +++ ++++E E+ ++E + +Q E Sbjct: 1230 KYALDLLQVKENLEKRIGEIIVEKQQLEGCQQNLETVSKAKDNLLNELTSLKVEIQSYQE 1289 Query: 1482 IERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEIT 1541 E V++ EL+V E L + + L K + E ++ ++ L+N+ + L ++ Sbjct: 1290 KE-VQMKHELSVLENEHNILQENLDTLQKQVVELTVSASQKESELQNEVCKQEKLQEKAQ 1348 Query: 1542 NLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDL 1591 L+ +KI + + AS+ ++ + L + +N + L A ++E DL Sbjct: 1349 KLEKDAGDLQAKILEISTLASE-REAQISSLKDEINSQHLKA-KQSEDDL 1396 Score = 112 bits (269), Expect = 9e-23 Identities = 201/1063 (18%), Positives = 444/1063 (41%), Gaps = 79/1063 (7%) Query: 94 LANTLKQKEILMEKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKE 153 L L +E L E+ ++ +++ + IV + V+ L +K+ Sbjct: 450 LQQELSHQETLREQTQELEKIKREELEGIVSELQAKIIEVSSIASEREACVSSLQYEMKD 509 Query: 154 KDNALSVLQVKMKI-METTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXE 212 + + + ++ M+ + +LQE ++ + I K E Sbjct: 510 QLSKAKQCEADLRNEMKEKVGNLQELLDAANHGIAEKEHHLESLNQSLKQMELLYCQKEE 569 Query: 213 D--TKQQMTKMQENFIAMEAEWKDEKQR----LLKDIESKDVRISSLEEANKLLEAARFE 266 + QQ + EN IA + + DE Q+ L + + R+SSL+E + + Sbjct: 570 EIIASQQAKEQLENNIAEQKQQLDEIQQNREILRNERDHLSTRVSSLQEEIHCSQQEFSD 629 Query: 267 ISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSI--EPSCEEKTEIEEKG-SLEIANMTE 323 + +H+ L ++L + + + + + EK LE E Sbjct: 630 LQTDHNVLKEKLVNLQNQLEQAMITASQKESELLLLQQELSHQETLREKALELEAIKREE 689 Query: 324 LTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMK 383 KK++ L+ ++ + E ++ ++ E + + + + R+ + +K Sbjct: 690 FEKKVKELQDRILEVSTLASQREAQVISLENEMRDQQLSANQSKDNLCRE-WQEKLGILK 748 Query: 384 SPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXX 443 +S + ++D + ++ ++EMV+ KD+++ +++D Sbjct: 749 GELDVVSRDAADKDHQLESLDQKLKEMEMVVLQKEKDVMETHQ--AKEDLEKRIAELEEC 806 Query: 444 GKDTLIAQLQLEHQQHMEGPSL---IHVGTNTE-DVNEIAKVQEQLKQELNDEIKDVNVK 499 + I + + +H E SL IH +T+ + V E L + + + K Sbjct: 807 KQKLEIMRNERDHLS-TEVASLKEEIHSYQDTQMQKQQTISVLEVENNALKENMAALE-K 864 Query: 500 DLIEKLKSAEEQITQLNDEI-------DAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSD 552 L E++ +A ++ ++L +++ + A + I + +++++Q + S ++ Sbjct: 865 QLAEEITTASQKNSELQNKLHQQESLHEKAQELEIGRHEEFERRVRELQAKVQEVSTLA- 923 Query: 553 SNKEIVR--LTEELH-HLSQKVAE------LEEEKGNLQLHL----VDYDSGRMIESDVY 599 S KE V L EEL HL KV+E LEE+ LQ + D S + + Sbjct: 924 SEKEAVAYSLQEELTGHLKAKVSEDDLRRVLEEKVETLQREIETASCDATSKDGLLQTLD 983 Query: 600 KKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEI 659 +K+ +ME L + + A+ +++ K DL +E++ L K E+E L + ++ ++ Sbjct: 984 QKLRQMEMLCQQKEDAVFEIQNSKEDLQKEMNELVSKNQELEGCLQHLEMVKKEKDLLSN 1043 Query: 660 KSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMD 719 + L+EQI+ S K+ + K+ +E++ LE+ D+ K + ++Q Sbjct: 1044 EVTSLKEQINDQSLRAKQSE--ADLCKVFEEKIETLQGQLESSSRDVSEK-EKHLQTLHQ 1100 Query: 720 LTDKLEKMSAEKISELLAKINHEE--QSKIQTQFGIDAKIQERDLYIENIESELSKYKSR 777 +++ + +K + +L N +E Q KI +++ +E ++SE + Sbjct: 1101 KVSQMDLLCQQKENAVLEMQNAKEDLQKKIDELVSEKQQLEGCLQNLEMVKSERDLLSTE 1160 Query: 778 ICRLEESIAVMEDRRYSLERKADQLGSYLQEKQK-------AYSEYTIQEDELVNRL--- 827 + +++ + D+ ++ D L L+EK K S ++D+L+ L Sbjct: 1161 VTSIKDQ---LNDQDLKAKQSEDDLRKVLEEKIKNLQGQLETASRDVSEKDQLLQTLDQK 1217 Query: 828 AVLMDH-DRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRT 886 MD + EK L++ + L+K+ ++ E Q L+ +++ A N Sbjct: 1218 VTQMDQLYKKKEKYALDLLQVKENLEKRIGEIIVEKQQLEGCQQNLETVSKAKDNLLNEL 1277 Query: 887 DLAESESTKYQTQLRDLESNLKRITHEHQTL---IVQKKKEIEDLEIEFNTQIESAIRDK 943 + E YQ + ++ L + +EH L + +K++ +L + +Q ES ++++ Sbjct: 1278 TSLKVEIQSYQEKEVQMKHELSVLENEHNILQENLDTLQKQVVELTVS-ASQKESELQNE 1336 Query: 944 KVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVE-ELNKMNLELIDKHVQKQQTQSPD 1002 EK ++ + + + LQ I L E +++ + E+ +H++ +Q++ D Sbjct: 1337 VCKQEKLQEKAQKLEKDAGDLQAKILEISTLASEREAQISSLKDEINSQHLKAKQSED-D 1395 Query: 1003 YTEQYINEINKLNALLK-------QKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTT 1055 + +I L L+ KD+ + LNQK+ + + E+ + + Sbjct: 1396 LLRVFEEKIENLQGQLEIARLDVSDKDQLLQTLNQKLKQME----ELCKQKETCVLEMHQ 1451 Query: 1056 KLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKET 1098 E++E+++ V Q S+Q+ + L++L R++ D +K L +T Sbjct: 1452 TKEDLEKKI--VELQADKSQQNQQNLEML-RQEKDHLKSLNQT 1491 Score = 106 bits (254), Expect = 6e-21 Identities = 192/1080 (17%), Positives = 461/1080 (42%), Gaps = 81/1080 (7%) Query: 498 VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEI 557 ++++ +L AE+++ +L ++A K+ +L K++ + + ++KE Sbjct: 4 LRNVFSQLARAEQEVAKLTVVHESAQTEW---KNRKELLEKELNEAV--------THKEC 52 Query: 558 VRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIE-----SDVYKKMIEMENL-AET 611 L+E++ L K++ LE+E Q G ++E S + KK E+E L AE Sbjct: 53 --LSEQVLILQGKISVLEDELKKAQSQERGEVLGPIMELQESISHLEKKKAEVEALLAEE 110 Query: 612 RL---KAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQI 668 R K + L+ FDL + ++ ++ + + +++ L ++ S Q+ + + V +Q+ Sbjct: 111 RCSFEKETARLQLVVFDLEKSINSIRLERETLQEALKTQKEMLSAQISALERDVSRLQQV 170 Query: 669 DALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMS 728 + ++ +++ +L+ +E+L G + L+ + ++Q E D + + Sbjct: 171 EVQLTAEIKISA---DLRQQREELEGKVASLDRMVHSLHAEIQGLEVERASQQDAINSL- 226 Query: 729 AEKISEL-LAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAV 787 IS+L +A+ +E K K++E + + +E + K+ C +++ + Sbjct: 227 ---ISDLQIARATVQEYEK---------KLEEH----QKVVAENNSLKNEACTMQQELNN 270 Query: 788 MEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHE 847 L+ + ++L E++ SE ++ + L + L + + ++++ + E Sbjct: 271 HLKAIGDLQAEVNELRFEKTEEENKVSEALVKIESLQTEILHLCEKISLKDEEIRNLTKE 330 Query: 848 NKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANR-TDLAESESTKYQTQLRDLE-- 904 + + + +++ E+N + + ++ + VEK + A S +++ Q Q+ L Sbjct: 331 YESVDNELKLVKEQNVEINAMIKSNRKEHEETVEKLQQELHCAASAASEKQEQMLVLSAE 390 Query: 905 -SNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQ 963 ++LK + QK++E+ LE + N E+ + L E + ++ Sbjct: 391 VTSLKEQICRYSENEAQKQQELSILEAQHNVLKENLTSLQNQLAEATTSASQKESEF-IL 449 Query: 964 LQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDE 1023 LQ+ ++ E L +EL K+ E ++ V + Q + + + + ++ A + Sbjct: 450 LQQELSHQETLREQTQELEKIKREELEGIVSELQAKIIEVS----SIASEREACVSSLQY 505 Query: 1024 EIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQI 1083 E + +++ A+ + ++ + K+ L+ + L Q +++++ Sbjct: 506 E---MKDQLSKAKQCEADLRNEMKEKVGNLQELLDAANHGIAEKEHHLESLNQSLKQMEL 562 Query: 1084 LVREQDDQIKELKETKLTFEMNIPKTEGMI--ISSTIEPMSDDANNVDXXXXXXXXXXXX 1141 L +++++I ++ K E NI + + + I E + ++ +++ Sbjct: 563 LYCQKEEEIIASQQAKEQLENNIAEQKQQLDEIQQNREILRNERDHL-STRVSSLQEEIH 621 Query: 1142 LKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKS 1201 QE + + +VL+E+ L +L++ Q E+ L ++ +QE + + Sbjct: 622 CSQQEFSDLQTDHNVLKEKLVNLQNQLEQAMITASQKES-ELLLLQQELSHQETLREKAL 680 Query: 1202 KLEQLNTEN-DNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQ 1260 +LE + E + + + + +S+ QR ++ L + + ++ +++ L + Sbjct: 681 ELEAIKREEFEKKVKELQDRILEVSTLASQREAQVISL-ENEMRDQQLSANQSKDNLCRE 739 Query: 1261 LSAFESKYEQLLDSVQSSTQEETNKIVTMEQ-VTSLQNKLQDKEEHLRNLQEKYADVINQ 1319 + LD V ++ +++ +++Q + ++ + KE+ + + D+ + Sbjct: 740 WQEKLGILKGELDVVSRDAADKDHQLESLDQKLKEMEMVVLQKEKDVMETHQAKEDLEKR 799 Query: 1320 IEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYK--QMQEQSILNINE-ENAQ 1376 I +E+E+ K L+ E SY+ QMQ+Q +++ E EN Sbjct: 800 I----AELEECKQKL-EIMRNERDHLSTEVASLKEEIHSYQDTQMQKQQTISVLEVENNA 854 Query: 1377 LKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFEN 1436 LK++ + A K EL ++L ++S +++K E I R++EFE Sbjct: 855 LKEN---MAALEKQLAEEITTASQKNSELQNKLHQQES-LHEKAQELEI---GRHEEFER 907 Query: 1437 VRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKIT 1496 ++L + + L EKE A+ E H + E ++ RV L E++ Sbjct: 908 RVRELQAKVQEVSTLASEKE---AVAYSLQEELTGHLKAKVSEDDLRRV-LEEKVETLQR 963 Query: 1497 ESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQK 1556 E + + + L+ K +M+ + +E + + + +LQ + SK Q+ Sbjct: 964 EIETASCDATSKDGLLQTLDQKLRQMEMLCQQKEDAVFEIQNSKEDLQKEMNELVSKNQE 1023 Score = 92.3 bits (219), Expect = 1e-16 Identities = 169/918 (18%), Positives = 386/918 (42%), Gaps = 56/918 (6%) Query: 213 DTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKD---VRISSLEEANKLLEAARFEISL 269 D Q+ + + ME +++ +++ ++K+ RI+ LEE + LE R E Sbjct: 760 DKDHQLESLDQKLKEMEMVVLQKEKDVMETHQAKEDLEKRIAELEECKQKLEIMRNERDH 819 Query: 270 EHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSC--EEKTEIEEKGSLEIANMTELTKK 327 +++A E+ ++ +E + E +E++ + EI ++ + Sbjct: 820 LSTEVASLKEEIHSYQDTQMQKQQTISVLEVENNALKENMAALEKQLAEEITTASQKNSE 879 Query: 328 IELLEHLNCQIRQTNKELE-NKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPW 386 ++ H + + +ELE + + + + ++ S L S K A ++ Sbjct: 880 LQNKLHQQESLHEKAQELEIGRHEEFERRVRELQAKVQEVSTLASEKEA--VAYSLQEEL 937 Query: 387 SQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKD 446 + +++D +++ + ++ L+ I++ + D K+ ++ D K+ Sbjct: 938 TGHLKAKVSEDDLRRVLEEKVETLQREIETASCDATSKDGLLQTLDQKLRQMEMLCQQKE 997 Query: 447 TLIAQLQ-------------LEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEI 493 + ++Q + Q +EG L H+ ++ + ++ LK+++ND+ Sbjct: 998 DAVFEIQNSKEDLQKEMNELVSKNQELEG-CLQHLEMVKKEKDLLSNEVTSLKEQINDQS 1056 Query: 494 KDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDS 553 + + K EE+I L ++++++++ + K H L Q +D + ++ Sbjct: 1057 LRAKQSEA-DLCKVFEEKIETLQGQLESSSRD-VSEKEKHLQTLHQKVSQMDLLCQQKEN 1114 Query: 554 NKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEM--ENLAET 611 ++ + L +K+ EL EK L+ L + + + E D+ + + L + Sbjct: 1115 --AVLEMQNAKEDLQKKIDELVSEKQQLEGCLQNLEMVKS-ERDLLSTEVTSIKDQLNDQ 1171 Query: 612 RLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQS--DQVCSEIKSVHLEEQID 669 LKA + + L +++ LQ + + +++ QL DQ +++ ++ +++ Sbjct: 1172 DLKAKQSEDDLRKVLEEKIKNLQGQLETASRDVSEKDQLLQTLDQKVTQMDQLYKKKEKY 1231 Query: 670 ALSAS--KKELALVIENLKLDKEQLYGTIKDLEN---DKEDIMNKLQNYIQENMDLTDKL 724 AL K+ L I + ++K+QL G ++LE K++++N+L + E +K Sbjct: 1232 ALDLLQVKENLEKRIGEIIVEKQQLEGCQQNLETVSKAKDNLLNELTSLKVEIQSYQEKE 1291 Query: 725 EKMSAE-KISELLAKINHEEQSKIQTQF-GIDAKIQERDLYIENIESELSKYKSRICRLE 782 +M E + E I E +Q Q + +++ ++N + K + + +LE Sbjct: 1292 VQMKHELSVLENEHNILQENLDTLQKQVVELTVSASQKESELQNEVCKQEKLQEKAQKLE 1351 Query: 783 ESIA-----VMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDH-DRV 836 + ++E + ER+A Q+ S E + + ED+L+ +++ Sbjct: 1352 KDAGDLQAKILEISTLASEREA-QISSLKDEINSQHLKAKQSEDDLLRVFEEKIENLQGQ 1410 Query: 837 VEKQLLEIEHENKELQKKNQIL--LEEN-QNLQISLSDMQQHYNALVEKANRTDLAESES 893 +E L++ +++ LQ NQ L +EE + + + +M Q L +K +S+ Sbjct: 1411 LEIARLDVSDKDQLLQTLNQKLKQMEELCKQKETCVLEMHQTKEDLEKKIVELQADKSQQ 1470 Query: 894 TKYQTQ-LRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEK 952 + + LR + +LK + + +K +LE+ Q S + KK + E+ Sbjct: 1471 NQQNLEMLRQEKDHLKSLNQTIRRECEASRKIRAELELNVEEQTASILALKKASQQWEEQ 1530 Query: 953 NIEYVTQLEAQ---LQEYKNNIENLNMNVEELNKMNLEL--IDKHVQKQQTQSPDYTEQY 1007 N E + QL+A+ ++ YK +E + ++ LE ++K +++ S + Sbjct: 1531 NQELLEQLKAKTEAVEHYKAQVEKAMNHYNGKKQLLLEAQELNKTLEQSLEVSKREAKAL 1590 Query: 1008 INEINKLNALLKQKD--EEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQ 1065 E+ L Q + E+ +A K AQV + + ++A L E Sbjct: 1591 ETELTLARMELNQANDKEKSLAAKVKTLEAQVDFADRQLREKRRIADDGEDLRQKENLYF 1650 Query: 1066 RVSKQLLDSKQHNEELQI 1083 RV ++ D+ + E ++ Sbjct: 1651 RVPEKQQDTSADSLEFEL 1668 >UniRef50_UPI0000E7FDD2 Cluster: PREDICTED: similar to trans-Golgi p230; n=3; Gallus gallus|Rep: PREDICTED: similar to trans-Golgi p230 - Gallus gallus Length = 2202 Score = 152 bits (368), Expect = 9e-35 Identities = 302/1473 (20%), Positives = 619/1473 (42%), Gaps = 119/1473 (8%) Query: 150 TIKEKDNALSVLQVKMKIMETTILDLQEKIN--EKDQIIEAKNKATTXXXXXXXXXXXXX 207 +++EKD +SVLQ ++ +++ + + Q I + + E + ++ T Sbjct: 242 SLEEKDQLISVLQTQVSLLKQRLQNGQIGIELPDPNNQSEPQVQSQTKEINAENIVEPGN 301 Query: 208 XXXXEDTKQQMTKMQENFIAMEAEW-KDEKQRLLKDIESKDVRISSLEEANKLLEAARFE 266 +T Q K QEN + E + K+R + K+ LEE + LE + Sbjct: 302 SVKTLETLNQRVKRQENLLQRCKEMIRSHKERCAQLTNEKEALQEQLEERLQELEKMKDL 361 Query: 267 ISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEI-ANMTELT 325 E +KL +L + ++ + E E++E+ ++ A + ++T Sbjct: 362 HMGEKTKLITQLRDAKNLIEQLEQDKGMVIAET-KRQMHETLEMKEEEVAQLRARIKQIT 420 Query: 326 KK-IELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLIS--RKSGRNTASKM 382 + EL E R +ELE L +A + I K+ + Sbjct: 421 TQGEELKEQKEKFERAAFEELEKALGMAQRTEEARKKLQAEMDEKIKAVEKANEEERVNL 480 Query: 383 KSPWSQLSSETLNQDTDKKINKNEIAKLEMV--IQSLNKDL-VDKEYVISEKDTXXXXXX 439 + +++ E + + KK +++ +A+LE + + KD +++ E++ Sbjct: 481 QQELTRVKQEVV--EIMKKSSEDRVAELEKLHKEEMATKDQELNERLQAQEREFQEKMKA 538 Query: 440 XXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDV-NEIAKVQEQLKQELND------E 492 + + LQ + QQ E +L + + + +E K E++ QE+ E Sbjct: 539 ALEKNQSECLKTLQEQEQQ--ESLALEELELQKKAIQSECDKKLEEMHQEVETFKTRILE 596 Query: 493 IKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKL---KQMQKTIDNFSK 549 ++ K + K +EE T + E NK + + HK +L KQ Q+ + Sbjct: 597 LESSLAKCSQDDKKRSEELSTLMESEKKQHNKEVSDIVEKHKEELENVKQQQEKLWTEKL 656 Query: 550 VSDSNKEIVRLTEELHHLSQKVAELEEEKGNL-QLHLVDYDSGRMIESDVYKKMIEMENL 608 + ++ + + Q++ + +EK + + H+ + + + + DV K E+E L Sbjct: 657 QILQQQHVIEIEKMREKQEQEIDTILKEKETVFRTHIEEMNEKTLEKLDV--KQTELETL 714 Query: 609 AETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQI 668 + +A+ + + DL QEL L+ K E + + + + +Q E++ + E +I Sbjct: 715 SSELSEALKVRQ----DLEQELSELKSKVGEAKQEFEGKLEAERNQHKEEVEIMLKEHEI 770 Query: 669 ---DALSASKKELALVIENLKLDKEQLYGTIKDLEND-KEDIMNKLQNYIQENMDLTDKL 724 D K+EL ++L+ +KE+L K E + KE +Q + L + Sbjct: 771 SIQDVEKVLKEELNQTKQSLE-EKERLLEEAKTREQELKESAQRSEAELVQVSARLME-- 827 Query: 725 EKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDL--YIENIESELSKYKSRICRLE 782 +S + S AK EE +K+Q + +D K ++ L + ES+L++ K+ LE Sbjct: 828 ASLSQQNTSNEQAKQYEEELAKLQQKL-MDLKGEKLQLSEQLVRTESQLNEVKN---ELE 883 Query: 783 ESIAVMEDRRYSLERKADQLGSYLQEKQKAY-SEYTIQEDELVNRLAVLMDHDRVVEKQL 841 I+ + + + L+ ++D+ + + Y S+ ++E L + + +E + Sbjct: 884 LYISQVHELKQQLQEQSDENTQKVMSLTQQYESQLKDLQEEADKAKQTLTERENDIE-HV 942 Query: 842 LEIEHENKELQKKNQILLEENQNLQISLSDMQQHY-NALVEKANRTDLAESESTK----Y 896 ++++E E K+ + EE +S +Q Y N L + N+ + + +S + + Sbjct: 943 KKVQNEEMEELKQKLLATEER------ISTLQGDYENKLKRQENKMEKMKQKSKEMQETF 996 Query: 897 QTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEY 956 + +L + ES LK+ Q QK+ E +E + I D K E N + Sbjct: 997 KKKLAEQESKLKKELENKQLEFSQKESEFNAKMLEMAHASSAGINDAV---SKLESNQK- 1052 Query: 957 VTQLEAQLQEYKNNIENLNMNVE-ELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLN 1015 QLE+ + +K +E ++ + E +LN+ EL +KH + Q + + + ++ + Sbjct: 1053 -EQLESLAEAHKRELEEISRSWEKKLNQQAEELQEKHEMELQEKEQELGD-LKEKLATFS 1110 Query: 1016 ALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEE----EMQRVSKQL 1071 A + EI L ++ + + + + LAQ + L N E ++Q++ L Sbjct: 1111 AEKEGSRTEITRLKEEQVKRNETLKQLQEELKQSLAQMSA-LSNSESGLKAQLQKLEGDL 1169 Query: 1072 LDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXX 1131 S + LQ + Q I+E + ++T + KT + + S D N + Sbjct: 1170 SQSLKEKSGLQEQISRQ-KAIEEKDKARITELADKLKTLEEKLQTLQSSHSKDRENYEKK 1228 Query: 1132 XXXXXXXXXXLK--VQEEEEFIQERSVLQEQSAKLNTELQECYTK--IIQLETLNTELTG 1187 +K V + + + + VL + K N +++C K I+ + + E Sbjct: 1229 IEAFQLQETEVKELVAQLDAYWKSAEVLLQ--TKSNELIEKCNEKIGIVTCKIADCERQA 1286 Query: 1188 HDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQRE 1247 V + I ++ ++QL E DN++ + +R I V ++ +L K+ Q++ Sbjct: 1287 -TKVKEAVIIKMNKSVQQLQ-EKDNVIKS---MRDDIEGLVTEK----EQLQKEGGHQKQ 1337 Query: 1248 ADFQKTEHELRV-QLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHL 1306 A TE E + QL S+ + S++ QE+ ++I T+ + N+L + E + Sbjct: 1338 A---ATEKETCITQLRKELSENINAVTSLREDLQEKESEISTLNKTI---NELNVRLESM 1391 Query: 1307 RNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQS 1366 +L EK A I +L ++ ++E++ +L + + +Q + + Sbjct: 1392 VSLTEKEA----AISLLSTQHQEERLQL-----------INQVQELSSSVELLRQEKASA 1436 Query: 1367 ILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTIT 1426 + ++ A+L + + D ++K LE+++ K E K E Sbjct: 1437 LEQVDHCTAKLSEWKTKAQTRFTQNHEAIKDLQSK-LEVSNTQATKKGEELDKLKE---E 1492 Query: 1427 LTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVK 1486 L Q+ + ++++ L E E RIE E +EL I ++ E H QK SE + +K Sbjct: 1493 LAQQGKDLDSLKSVLEEKENRIEKQESELTAELKIQAARVAELEEH--IAQKTSENDSLK 1550 Query: 1487 LIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNM 1546 EEL + E + ++ E+ + L++ E + L+ E +++ L +EI +L+ Sbjct: 1551 --EELK-RYHEQKDMEQK--EVARQLQQAEKVAFEKDSRLKEAEEKVLNLENEIGSLKAE 1605 Query: 1547 VRASSSKIQKHVSFASDTKQGRDEQLDNTMNKE 1579 A + + S +K+ ++L+ +N E Sbjct: 1606 CEAKEREFDQMKSAILKSKEEELKELEERLNAE 1638 Score = 144 bits (350), Expect = 1e-32 Identities = 281/1431 (19%), Positives = 588/1431 (41%), Gaps = 120/1431 (8%) Query: 97 TLKQKEILMEKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDN 156 +L++KE L+E+ K ++ K S+ R L + K+ + Sbjct: 789 SLEEKERLLEEAKTREQELKESAQ---RSEAELVQVSARLMEASLSQQNTSNEQAKQYEE 845 Query: 157 ALSVLQVKMKIMETTILDLQEK-INEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTK 215 L+ LQ K+ ++ L L E+ + + Q+ E KN+ E+T+ Sbjct: 846 ELAKLQQKLMDLKGEKLQLSEQLVRTESQLNEVKNELELYISQVHELKQQLQEQSDENTQ 905 Query: 216 QQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLA 275 + M+ Q+ E++ KD ++ K ++ R + +E K+ E L+ LA Sbjct: 906 KVMSLTQQ----YESQLKDLQEEADKAKQTLTERENDIEHVKKVQNEEMEE--LKQKLLA 959 Query: 276 QELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLN 335 E + + +E ++ E++E ++A KK LE+ Sbjct: 960 TE--ERISTLQGDYENKLKRQENKMEKMKQKSKEMQETFKKKLAEQESKLKKE--LENKQ 1015 Query: 336 CQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLS---SE 392 + Q E K+ M S A + + ++ + A K ++S + Sbjct: 1016 LEFSQKESEFNAKMLEMAHASSAGINDAVSKLESNQKEQLESLAEAHKRELEEISRSWEK 1075 Query: 393 TLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVIS-EKD---TXXXXXXXXXXGKDTL 448 LNQ ++ K+E+ +L+ Q L DL +K S EK+ T ++ Sbjct: 1076 KLNQQAEELQEKHEM-ELQEKEQELG-DLKEKLATFSAEKEGSRTEITRLKEEQVKRNET 1133 Query: 449 IAQLQLEHQQHMEGPSLIH-------------VGTNTEDVNEIAKVQEQLKQELNDEIKD 495 + QLQ E +Q + S + G ++ + E + +QEQ+ ++ E KD Sbjct: 1134 LKQLQEELKQSLAQMSALSNSESGLKAQLQKLEGDLSQSLKEKSGLQEQISRQKAIEEKD 1193 Query: 496 -VNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLK---LKQMQKTIDNFSKVS 551 + +L +KLK+ EE++ L +N K +L+ +K++ +D + K + Sbjct: 1194 KARITELADKLKTLEEKLQTLQSSHSKDRENYEKKIEAFQLQETEVKELVAQLDAYWKSA 1253 Query: 552 D------SNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEM 605 + SN+ I + E++ ++ K+A+ E + ++ ++ +M +S +++ E Sbjct: 1254 EVLLQTKSNELIEKCNEKIGIVTCKIADCERQATKVKEAVII----KMNKS--VQQLQEK 1307 Query: 606 ENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVH-- 663 +N+ ++ I L ++K L +E +Q E E + + + S+ + + + S+ Sbjct: 1308 DNVIKSMRDDIEGLVTEKEQLQKEGGHQKQAATEKETCITQLRKELSENI-NAVTSLRED 1366 Query: 664 ---LEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDL 720 E +I L+ + EL + +E++ + + I L ++ +L N +QE Sbjct: 1367 LQEKESEISTLNKTINELNVRLESM-VSLTEKEAAISLLSTQHQEERLQLINQVQELSSS 1425 Query: 721 TDKL--EKMSA-EKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSR 777 + L EK SA E++ AK++ E ++K QT+F Q + I++++S+L ++ Sbjct: 1426 VELLRQEKASALEQVDHCTAKLS-EWKTKAQTRF-----TQNHEA-IKDLQSKLEVSNTQ 1478 Query: 778 ICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVV 837 + E + +++ + D L S L+EK+ + QE EL L + + Sbjct: 1479 ATKKGEELDKLKEELAQQGKDLDSLKSVLEEKENRIEK---QESELTAELKIQAARVAEL 1535 Query: 838 EKQLLEIEHENKELQKKNQILLEENQNLQISLS-DMQQHYNALVEKANRTDLAESESTKY 896 E+ + + EN L+++ + E+ Q ++ +QQ EK +R AE + Sbjct: 1536 EEHIAQKTSENDSLKEELKRYHEQKDMEQKEVARQLQQAEKVAFEKDSRLKEAEEKVLNL 1595 Query: 897 QTQLRDLESNLKRITHEHQ----TLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEK 952 + ++ L++ + E ++ K++E+++LE N + + D K E+ Sbjct: 1596 ENEIGSLKAECEAKEREFDQMKSAILKSKEEELKELEERLNAENSCKLADLKKKAEQKIG 1655 Query: 953 NI--EYVTQLEAQLQEYK----NNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQ 1006 +I E V Q+E + Q+ K N + +L V+E + +E +++ + K S + + Sbjct: 1656 SIKRELVRQMEEKEQQLKQDRENQVRHLEQKVQE-REAKIESLEEKM-KSVRDSTELERE 1713 Query: 1007 YINEINKLNALLKQKDEEIIALNQ-----KINNAQ---VSYMSMVSDYESKLAQFTTKLE 1058 + +I A ++Q+ E+I Q KIN Q + ++ YES+ + L Sbjct: 1714 MLQKIESTKAAVEQEKNEVIKSVQQTHEEKINKLQKDLIEKNKLLQKYESEQREGIDSLL 1773 Query: 1059 NMEEEMQRVSKQL-LDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISST 1117 ++ + + + K+L K+H EE + +++ ++ K+ L + + E Sbjct: 1774 ELQSKQEELLKKLECAEKRHREEQSVTEGLREELEEQAKKYSLLVDEHARCGE-----QK 1828 Query: 1118 IEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKI-- 1175 ++ + D+ V+ LK +E + +Q++ L+E++ +L + K Sbjct: 1829 VKELEDNLAKVNEVHKTELEDRS-LKYEENLKSLQQQ--LEERNDRLKAFEENAEEKAKS 1885 Query: 1176 -IQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFE 1234 ++L+ L ++ Q ++ + + + ++L + ++L + LR +D E Sbjct: 1886 GLELQKLLGDMQNQQKDLQAKLEEAEREKQKLRKDVNSLQKDLRTLRKEHQQELDIVKKE 1945 Query: 1235 IAELWKQHLAQREADFQ--------KTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKI 1286 E +Q + + D + + E QL+ E + E + S QE +++ Sbjct: 1946 SLEEMEQKIRCEQEDIELKHSSTLKQLMREFNTQLAQKEMELETAVKETISKAQEVESEL 2005 Query: 1287 VTMEQV--TSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXX 1344 + Q+ T L K+ +K++ L+ +KY +++ E + E Sbjct: 2006 IENHQIETTQLHKKIAEKDDDLKRTVKKYEEILEAREEEMTTKVHELQTQLEELQKEYKQ 2065 Query: 1345 XXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLE 1404 +EN + ++Q Q N K R+ + E K+ Sbjct: 2066 RMAEKDHRNSENVTIAELQAQLAQKTTLVNDS-KLKEQEFKEQIHVLEDRLKNYEKKMYV 2124 Query: 1405 LTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEK 1455 + +D + H ++L EFE +R+ L EY E T K Sbjct: 2125 TSVGTPYRDGNL----HHTDVSLFGEPTEFEYLRKVLFEYMMGRETKTMAK 2171 Score = 142 bits (344), Expect = 7e-32 Identities = 303/1494 (20%), Positives = 608/1494 (40%), Gaps = 117/1494 (7%) Query: 154 KDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXED 213 +D + ++ + M T +L E++ +++ + K KA E Sbjct: 500 EDRVAELEKLHKEEMATKDQELNERLQAQEREFQEKMKAALEKNQSECLKTLQEQEQQES 559 Query: 214 TKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSK 273 + ++Q+ I E + K E+ +++E+ RI LE + + S E S Sbjct: 560 LALEELELQKKAIQSECDKKLEEMH--QEVETFKTRILELESSLAKCSQDDKKRSEELST 617 Query: 274 L--AQELEQXXXXXXXXXXXXXXL--AKQSIEPSCEEKTEI-EEKGSLEIANMTELTKK- 327 L +++ + L KQ E EK +I +++ +EI M E ++ Sbjct: 618 LMESEKKQHNKEVSDIVEKHKEELENVKQQQEKLWTEKLQILQQQHVIEIEKMREKQEQE 677 Query: 328 IE-LLEH----LNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKM 382 I+ +L+ I + N++ KL TE + +SS + L R+ S++ Sbjct: 678 IDTILKEKETVFRTHIEEMNEKTLEKLDVKQTELETLSSELSEA--LKVRQDLEQELSEL 735 Query: 383 KSPWSQLSSETLNQ-DTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXX 441 KS + E + + ++ +K E+ E++++ + D E V+ E+ Sbjct: 736 KSKVGEAKQEFEGKLEAERNQHKEEV---EIMLKEHEISIQDVEKVLKEE---LNQTKQS 789 Query: 442 XXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQE-QLKQE--LNDEIK--DV 496 K+ L+ + + Q+ E + E V A++ E L Q+ N++ K + Sbjct: 790 LEEKERLLEEAKTREQELKESAQR----SEAELVQVSARLMEASLSQQNTSNEQAKQYEE 845 Query: 497 NVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSN-K 555 + L +KL + + QL++++ + +VK+ +L + Q+ + + SD N + Sbjct: 846 ELAKLQQKLMDLKGEKLQLSEQLVRTESQLNEVKNELELYISQVHELKQQLQEQSDENTQ 905 Query: 556 EIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKA 615 +++ LT++ ++ +L+EE + L + ++ IE + EME L + L Sbjct: 906 KVMSLTQQYE---SQLKDLQEEADKAKQTLTEREND--IEHVKKVQNEEMEELKQKLLAT 960 Query: 616 ISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASK 675 + + + D +L + K ++++ K ++ + ++ + + E + L S+ Sbjct: 961 EERISTLQGDYENKLKRQENKMEKMKQKSKEMQETFKKKLAEQESKLKKELENKQLEFSQ 1020 Query: 676 KEL---ALVIENLKLDKEQLYGTIKDLE-NDKEDIMNKLQNYIQENMDLTDKLEKMSAEK 731 KE A ++E + + LE N KE + + + + +E +++ EK ++ Sbjct: 1021 KESEFNAKMLEMAHASSAGINDAVSKLESNQKEQLESLAEAHKRELEEISRSWEKKLNQQ 1080 Query: 732 ISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDR 791 EL K E Q K Q + K+ E +E+++ K + E++ +++ Sbjct: 1081 AEELQEKHEMELQEKEQELGDLKEKLATFSAEKEGSRTEITRLKEEQVKRNETLKQLQEE 1140 Query: 792 RYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENK-- 849 L++ Q+ + + ++ E +L L + +Q IE ++K Sbjct: 1141 ---LKQSLAQMSALSNSESGLKAQLQKLEGDLSQSLKEKSGLQEQISRQKA-IEEKDKAR 1196 Query: 850 --ELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNL 907 EL K + L E+ Q LQ S S +++Y +E L E+E + QL + Sbjct: 1197 ITELADKLKTLEEKLQTLQSSHSKDRENYEKKIEAFQ---LQETEVKELVAQLDAYWKSA 1253 Query: 908 KRITHEHQTLIVQKKKE-IEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQE 966 + + +++K E I + + A + K+ + K K+++ + + + ++ Sbjct: 1254 EVLLQTKSNELIEKCNEKIGIVTCKIADCERQATKVKEAVIIKMNKSVQQLQEKDNVIKS 1313 Query: 967 YKNNIENLNMNVEELNKMNLELIDKHVQKQQ--TQSPDYTEQYINEINKLNALLKQKDEE 1024 +++IE L E+L K +K+ TQ + IN + L L++K+ E Sbjct: 1314 MRDDIEGLVTEKEQLQKEGGHQKQAATEKETCITQLRKELSENINAVTSLREDLQEKESE 1373 Query: 1025 IIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSK-QLLDSKQH--NEEL 1081 I LN+ IN V SMVS E + A ++ EE +Q +++ Q L S +E Sbjct: 1374 ISTLNKTINELNVRLESMVSLTEKEAAISLLSTQHQEERLQLINQVQELSSSVELLRQEK 1433 Query: 1082 QILVREQDDQIKELKETKLTFEMNIPKTEGMI--ISSTIE-------PMSDDANNVDXXX 1132 + + D +L E K + + I + S +E ++ + + Sbjct: 1434 ASALEQVDHCTAKLSEWKTKAQTRFTQNHEAIKDLQSKLEVSNTQATKKGEELDKLKEEL 1493 Query: 1133 XXXXXXXXXLK--VQEEEEFIQER-----SVLQEQSAKLNTELQE-CYTKIIQLETLNTE 1184 LK ++E+E I+++ + L+ Q+A++ EL+E K + ++L E Sbjct: 1494 AQQGKDLDSLKSVLEEKENRIEKQESELTAELKIQAARV-AELEEHIAQKTSENDSLKEE 1552 Query: 1185 LTGH----DVVNQEQINQLKSKLEQLNTENDNLLSTVAE----LRSSISS---AVDQRGF 1233 L + D+ +E QL+ + E++ E D+ L E L + I S + + Sbjct: 1553 LKRYHEQKDMEQKEVARQLQ-QAEKVAFEKDSRLKEAEEKVLNLENEIGSLKAECEAKER 1611 Query: 1234 EIAELWKQHLAQREADFQKTEHELRVQ----LSAFESKYEQLLDSV------QSSTQEET 1283 E ++ L +E + ++ E L + L+ + K EQ + S+ Q +E+ Sbjct: 1612 EFDQMKSAILKSKEEELKELEERLNAENSCKLADLKKKAEQKIGSIKRELVRQMEEKEQQ 1671 Query: 1284 NKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILR---SEIEDEKVAFXXXXXX 1340 K QV L+ K+Q++E + +L+EK V + E+ R +IE K A Sbjct: 1672 LKQDRENQVRHLEQKVQEREAKIESLEEKMKSVRDSTELEREMLQKIESTKAAVEQEKNE 1731 Query: 1341 XXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLK--KSSXXXXXXXXXXXXRVNDA 1398 + N+ K + E++ L E+ Q + S ++ A Sbjct: 1732 VIKSVQQTHEE--KINKLQKDLIEKNKLLQKYESEQREGIDSLLELQSKQEELLKKLECA 1789 Query: 1399 EAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLV-EYEKRIEDLTYEKES 1457 E + E E E+ ++ +Y++ + DE +Q V E E + + ++ Sbjct: 1790 EKRHREEQSVTEGLREELEEQAKKYSLLV----DEHARCGEQKVKELEDNLAKVNEVHKT 1845 Query: 1458 ELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVA 1517 EL LK EN + Q E +R+K EE + K EL K L + Sbjct: 1846 ELEDRSLKYEENLKSLQ-QQLEERNDRLKAFEE------NAEEKAKSGLELQKLLGDMQN 1898 Query: 1518 KTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQ 1571 + ++Q LE E E L ++ +LQ +R + Q+ + EQ Sbjct: 1899 QQKDLQAKLEEAEREKQKLRKDVNSLQKDLRTLRKEHQQELDIVKKESLEEMEQ 1952 Score = 122 bits (293), Expect = 1e-25 Identities = 198/963 (20%), Positives = 408/963 (42%), Gaps = 82/963 (8%) Query: 657 SEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMN---KLQNY 713 S+I+S E +A S SK++L + ++ G +L + + I KLQ Sbjct: 147 SDIESETEEVSGNADSLSKEQLLQRLRRMERSLGNYRGKYAELVSAYQVIQREKKKLQGI 206 Query: 714 IQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSK 773 + ++ D + +I EL ++ ++Q+K Q DA ++E+D I +++++S Sbjct: 207 LSQSQD-------KALRRIGELREELQMDQQAKKHLQEEFDASLEEKDQLISVLQTQVSL 259 Query: 774 YKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDH 833 K R+ + I + + S Q+ S +E +E ++ V L L Sbjct: 260 LKQRLQNGQIGIELPDPNNQS----EPQVQSQTKE---INAENIVEPGNSVKTLETLNQR 312 Query: 834 DRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESES 893 + E L + + +++ L E + LQ L + Q +EK DL E Sbjct: 313 VKRQENLLQRCKEMIRSHKERCAQLTNEKEALQEQLEERLQE----LEKMK--DLHMGEK 366 Query: 894 TKYQTQLRDLESNLKRITHEHQTLIVQKKKEI-EDLEIEFNTQIESAIRDKKVLNEKYEK 952 TK TQLRD ++ ++++ + +I + K+++ E LE++ + R K++ + E Sbjct: 367 TKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEVAQLRARIKQITTQGEEL 426 Query: 953 NIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELID--KHVQKQQTQSPDYTEQYINE 1010 + A +E + + E K+ E+ + K V+K + +Q + Sbjct: 427 KEQKEKFERAAFEELEKALGMAQRTEEARKKLQAEMDEKIKAVEKANEEERVNLQQELTR 486 Query: 1011 I-NKLNALLKQKDEEIIALNQKINNAQVSY--MSMVSDYESKLAQFTTKLE-NMEEEMQR 1066 + ++ ++K+ E+ +A +K++ +++ + +++ +F K++ +E+ Sbjct: 487 VKQEVVEIMKKSSEDRVAELEKLHKEEMATKDQELNERLQAQEREFQEKMKAALEKNQSE 546 Query: 1067 VSKQLLDSKQHN----EELQI----LVREQDDQIKELKETKLTFEMNIPKTEGMI----- 1113 K L + +Q EEL++ + E D +++E+ + TF+ I + E + Sbjct: 547 CLKTLQEQEQQESLALEELELQKKAIQSECDKKLEEMHQEVETFKTRILELESSLAKCSQ 606 Query: 1114 --------ISSTIEPMSDDAN-NVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKL 1164 +S+ +E N V +K Q+E+ + ++ +LQ+Q Sbjct: 607 DDKKRSEELSTLMESEKKQHNKEVSDIVEKHKEELENVKQQQEKLWTEKLQILQQQHV-- 664 Query: 1165 NTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSK-LEQLNTENDNLLSTVAELRSS 1223 E+++ K Q + ++T L + V + I ++ K LE+L+ + L + +EL + Sbjct: 665 -IEIEKMREK--QEQEIDTILKEKETVFRTHIEEMNEKTLEKLDVKQTELETLSSELSEA 721 Query: 1224 ISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEET 1283 + D E++EL K + + + +F E +L + + + + E +L + S Q+ Sbjct: 722 LKVRQDLEQ-ELSEL-KSKVGEAKQEF---EGKLEAERNQHKEEVEIMLKEHEISIQDVE 776 Query: 1284 NKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXX 1343 V E++ + L++KE L + + ++ + RSE E +V+ Sbjct: 777 K--VLKEELNQTKQSLEEKERLLEEAKTREQELKESAQ--RSEAELVQVSARLMEASLSQ 832 Query: 1344 XXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVL 1403 + E + K +Q ++++ E QL + + ++V Sbjct: 833 QNTSNEQAKQYEEELAK--LQQKLMDLKGEKLQLSEQLVRTESQLNEVKNELELYISQVH 890 Query: 1404 ELTHQLELKDSEIYQK----THEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESEL 1459 EL QL+ + E QK T +Y L +E + +Q L E E IE + + E+ Sbjct: 891 ELKQQLQEQSDENTQKVMSLTQQYESQLKDLQEEADKAKQTLTERENDIEHVKKVQNEEM 950 Query: 1460 AILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAE-LNKALEEEVAK 1518 L+ K+ T+Q + E ++K E K+ + +K++ E K L E+ +K Sbjct: 951 EELKQKLLATEERISTLQGDYE-NKLKRQEN---KMEKMKQKSKEMQETFKKKLAEQESK 1006 Query: 1519 TNEMQTALENQEIEIVTLNDEI-TNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMN 1577 ++ LEN+++E E + M ASS+ I VS ++ + E L Sbjct: 1007 ---LKKELENKQLEFSQKESEFNAKMLEMAHASSAGINDAVSKLESNQKEQLESLAEAHK 1063 Query: 1578 KEL 1580 +EL Sbjct: 1064 REL 1066 >UniRef50_A2FU34 Cluster: Putative uncharacterized protein; n=1; Trichomonas vaginalis G3|Rep: Putative uncharacterized protein - Trichomonas vaginalis G3 Length = 1504 Score = 151 bits (367), Expect = 1e-34 Identities = 200/913 (21%), Positives = 425/913 (46%), Gaps = 89/913 (9%) Query: 476 NEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQIT--QLNDEIDAANKNMIKVKSNH 533 N++ + +L+ LN ++ + + E ++ ++ + DE+ A N + K Sbjct: 358 NQLNDDKHRLQSLLNITLQKMKGDNPSEDTNFTDDMLSLQRERDELFAKNSYLEKQLQRE 417 Query: 534 KLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRM 593 K+ ++ + S ++K I L + +A ++E + D ++ Sbjct: 418 KIHSTKLMAASEIESSTVPADKNIDDLWK------MYIAVVKENENRRDKEREDMETIVQ 471 Query: 594 IESDVY-KKMIEMEN--LAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQL 650 +++D+ KK +E +N L++T +K + L + K L+Q+++ + +++V L ++++L Sbjct: 472 MKNDLENKKQLERDNDELSKTVIKLQNELNANKV-LMQKINS-ELGFEKVVKMLNNLTEL 529 Query: 651 QSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKL 710 S+ E+ V L+E+ L + IE LK D E L IK+ ++ + L Sbjct: 530 VSNDDKEEL--VQLKEENKNLKTKNDKSKAKIEKLKKDLEDLKQEIKESQSKHGE---NL 584 Query: 711 QNYIQENMDLTDKLEKMSAE--KISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIE 768 QN I+ N D+++KL +++AE K++ +L +QS Q Q A +Q + ++N Sbjct: 585 QNMIENNKDISNKLNQLTAENAKLNSILQNYEKLKQSNSQLQNDYTA-LQNNNNQLQNNI 643 Query: 769 SEL-SKYKSRICR---LEESIAVMEDRR-------YSLERKADQLGSYLQEKQKAY---- 813 S+L +K +S L + ++ M D+ + L+ L S LQEK Y Sbjct: 644 SQLKAKIESADANSKNLSDQLSKMRDQNEYLIKQNHQLDNNISVLESKLQEKDNLYKNLS 703 Query: 814 ---SEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLS 870 S+ Q D+ +NR + L + + EK+L +++ + ++L K+N+ L EN + SL Sbjct: 704 EQLSKQKSQNDDFLNRTSSLENQKQNYEKELKDLKDKLEDLNKQNKALKNENDKMVTSLH 763 Query: 871 DMQQHYNALVEKANRTD---------LAESES-TKYQTQLRDLESNLKRITHEHQTLIVQ 920 +M+ ++L K +D L+ S S ++ QL+DL N ++ T + Sbjct: 764 NMETAKSSLEGKLEISDNMVKSLKDQLSNSSSISQSNKQLQDLYENERKETKALNEKMAA 823 Query: 921 KKKEIEDLEIEF-NTQIE-SAIRDKKVL----NEKY----EKNIEYVTQLEAQLQEYKNN 970 K+++ LE++ NT+ E ++++ ++ N+K +K V +LE L++ K + Sbjct: 824 LKQQMSLLEVKLHNTEAEGEKMKNENLMLKSENDKLKSDSDKTASQVEKLEKDLKKSKKD 883 Query: 971 IENLNMNVEELNKMN----LELIDKH-VQKQQTQSPDYTEQYINEINKLNAL---LKQKD 1022 + L + E+++ N ++ DK+ ++ + T+ EQY N+ K + + LK K Sbjct: 884 LSQLESDFEKISAENESLQKKIADKNKLKNETTEKSTLLEQYKNDNKKKDEIINQLKDKK 943 Query: 1023 EEIIALN-QKINNAQ---VSYMSMVSDY---ESKLAQFTTKLENMEEEMQRVSKQLL--- 1072 ++I N Q NN Q V S+ D ++ L + L+ + ++Q+++ + + Sbjct: 944 KKIKQENEQNKNNLQKVTVENTSLQKDLQKSQNDLQKSQNDLQKSQNDLQKLTTENVNLQ 1003 Query: 1073 -DSKQHNEELQILVREQD--DQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVD 1129 D ++ +LQ L +E++ + E K T++ + + + S E + D N + Sbjct: 1004 KDLQKVQSDLQKLQQEREKLQENMENKNTQMKGDFEKIRANYDKLKSDYEKLKSDNNQLQ 1063 Query: 1130 XXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHD 1189 + + + +Q +++ ++QS+ ++E+Q ++ Q++ N L + Sbjct: 1064 KEADENKQKLDKKEEKIQNLKLQIQNLQKDQSSMKSSEIQRLQNELEQMKANNKSLKENI 1123 Query: 1190 VVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREAD 1249 ++I Q K K + L + NL + + E++++++ + +L + LA + + Sbjct: 1124 EAKNKEIEQNKEKNKALKSNLTNLQNKINEIQNALTGKDKEN-----QLLQNELANKNKE 1178 Query: 1250 FQKTEHELRVQLSAFESKYEQLLDSVQSSTQE-ETNKIVTMEQVTSLQ---NKLQDKEEH 1305 QK + +L S ++ D + S ++ K ++Q +LQ KL+ + E Sbjct: 1179 IQKLKDDLEKAKSDKNKSQNEITDKLNSKLEKVMAEKEDLLKQNANLQAEMQKLKAENEK 1238 Query: 1306 LRNLQEKYADVIN 1318 L+ + +K IN Sbjct: 1239 LKGILKKKTAYIN 1251 Score = 133 bits (321), Expect = 4e-29 Identities = 204/1127 (18%), Positives = 483/1127 (42%), Gaps = 72/1127 (6%) Query: 458 QHMEGPSLIHVGTNTEDVNEIAKVQEQLKQ---ELNDEIKDVNVKDLI-EKLKSAEEQIT 513 Q E S + T + + E+ V + ++ E N +I ++ L E+L+ +++ Sbjct: 288 QKKEYLSNAKLDTISRQIRELRAVADNIQDDVIEANRKIDQNKIQVLTREQLEEENKRLN 347 Query: 514 QLNDEIDAANK--NMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKV 571 ++D++N N K + L + + DN S+ ++ +++ L E L K Sbjct: 348 LEKSQLDSSNNQLNDDKHRLQSLLNITLQKMKGDNPSEDTNFTDDMLSLQRERDELFAKN 407 Query: 572 AELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELH 631 + LE++ ++H + IES +++L + + + E+++ +++ Sbjct: 408 SYLEKQLQREKIHSTKLMAASEIESSTVPADKNIDDLWKMYIAVVKENENRRDKEREDME 467 Query: 632 ILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKE- 690 + Q +++E+K QL+ D E+ ++ Q + L+A+K + + L +K Sbjct: 468 TIVQMKNDLENK----KQLERDN--DELSKTVIKLQ-NELNANKVLMQKINSELGFEKVV 520 Query: 691 QLYGTIKDL--ENDKEDIMN---KLQNYIQENMDLTDKLEKMSAE------KISELLAKI 739 ++ + +L +DKE+++ + +N +N K+EK+ + +I E +K Sbjct: 521 KMLNNLTELVSNDDKEELVQLKEENKNLKTKNDKSKAKIEKLKKDLEDLKQEIKESQSKH 580 Query: 740 NHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKA 799 Q+ I+ I K+ + + S L Y+ +L++S + +++ +L+ Sbjct: 581 GENLQNMIENNKDISNKLNQLTAENAKLNSILQNYE----KLKQSNSQLQNDYTALQNNN 636 Query: 800 DQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILL 859 +QL + + + + L ++L+ + D + + KQ ++++ L+ K L Sbjct: 637 NQLQNNISQLKAKIESADANSKNLSDQLSKMRDQNEYLIKQNHQLDNNISVLESK----L 692 Query: 860 EENQNLQISLSD-MQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLI 918 +E NL +LS+ + + + + NRT E++ Y+ +L+DL+ L+ + +++ L Sbjct: 693 QEKDNLYKNLSEQLSKQKSQNDDFLNRTSSLENQKQNYEKELKDLKDKLEDLNKQNKALK 752 Query: 919 VQKKKEIEDLE----IEFNTQIESAIRDKKVLNEKYE-KNIEYVTQLEAQLQE-YKNNIE 972 + K + L + + + + I D V + K + N ++Q QLQ+ Y+N + Sbjct: 753 NENDKMVTSLHNMETAKSSLEGKLEISDNMVKSLKDQLSNSSSISQSNKQLQDLYENERK 812 Query: 973 NLNMNVEELN--KMNLELIDKHVQKQQTQSPDYTEQYI---NEINKLNALLKQKDEEIIA 1027 E++ K + L++ + + + + + +E +KL + + ++ Sbjct: 813 ETKALNEKMAALKQQMSLLEVKLHNTEAEGEKMKNENLMLKSENDKLKSDSDKTASQVEK 872 Query: 1028 LNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVRE 1087 L + + ++ + SD+E K++ L+ + ++ + + E+ + ++ Sbjct: 873 LEKDLKKSKKDLSQLESDFE-KISAENESLQKKIADKNKLKNETTEKSTLLEQYKNDNKK 931 Query: 1088 QDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEE 1147 +D+ I +LK+ K + + + + T+E S + K Q + Sbjct: 932 KDEIINQLKDKKKKIKQENEQNKNNLQKVTVENTSLQKDLQKSQNDLQKSQNDLQKSQND 991 Query: 1148 EEFIQERSV-LQEQSAKLNTELQECYTKIIQL----ETLNTELTGHDVVNQEQINQLKSK 1202 + + +V LQ+ K+ ++LQ+ + +L E NT++ G + ++LKS Sbjct: 992 LQKLTTENVNLQKDLQKVQSDLQKLQQEREKLQENMENKNTQMKGDFEKIRANYDKLKSD 1051 Query: 1203 LEQLNTENDNLLSTVAELRSSISSA---VDQRGFEIAELWKQHLAQREADFQKTEHELRV 1259 E+L ++N+ L E + + + +I L K + + ++ Q+ ++EL Sbjct: 1052 YEKLKSDNNQLQKEADENKQKLDKKEEKIQNLKLQIQNLQKDQSSMKSSEIQRLQNELE- 1110 Query: 1260 QLSAFESKYEQLLDSVQSSTQEETNKIVTMEQ-VTSLQNKLQDKEEHLRNLQEKYADVIN 1318 Q+ A ++ +++ ++ K ++ +T+LQNK+ + + L ++ + N Sbjct: 1111 QMKANNKSLKENIEAKNKEIEQNKEKNKALKSNLTNLQNKINEIQNALTGKDKENQLLQN 1170 Query: 1319 QIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSI---LNINEENA 1375 ++ EI+ K L ++ + +E + N+ E Sbjct: 1171 ELANKNKEIQKLKDDLEKAKSDKNKSQNEITDKLNSKLEKVMAEKEDLLKQNANLQAEMQ 1230 Query: 1376 QLKKSSXXXXXXXXXXXXRVNDAEAKVLELTH-----QLELKDSEIYQKTHEYTITLTQR 1430 +LK + +ND A+ ++L Q E+ ++ +K + T + Sbjct: 1231 KLKAENEKLKGILKKKTAYINDYYAQTVKLEQKSFGLQKEVDSLDVVKKKFDKLYTSREE 1290 Query: 1431 ND----EFENVRQQLVEYEKRIEDLTYE-KESELAILRLKMHENANHYETMQKESEIERV 1485 D E+ +++ ++ + + + Y+ K+ E+ + + E YE E + V Sbjct: 1291 IDNLFKEYGILQKLYNDHVDKDKLVPYKGKDIEVEKMPALISEVKKKYEDKLNNFEKQTV 1350 Query: 1486 KLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEM-QTALENQEI 1531 I NVK+ ++ + K AE+ +L+E A T + LEN+++ Sbjct: 1351 LTIYNENVKLIQACNHYKNAAEI--SLQERDATTKLLNDIILENEKL 1395 Score = 113 bits (271), Expect = 5e-23 Identities = 192/954 (20%), Positives = 427/954 (44%), Gaps = 122/954 (12%) Query: 212 EDTKQQMTKMQENFIAMEAEWKDEKQ--RLLKDIESKDVRISSLEEANK-LLEAARFEIS 268 E+ + + + E + M+ + +++KQ R ++ +++ + ANK L++ E+ Sbjct: 456 ENRRDKEREDMETIVQMKNDLENKKQLERDNDELSKTVIKLQNELNANKVLMQKINSELG 515 Query: 269 LEHS-KLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKK 327 E K+ L + ++++ ++ EK ++ ++ + K+ Sbjct: 516 FEKVVKMLNNLTELVSNDDKEELVQLKEENKNLKTKNDKSKAKIEKLKKDLEDLKQEIKE 575 Query: 328 IELLEHLNCQ-IRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSG--------RNT 378 + N Q + + NK++ NKL + E+ ++S + L S +N Sbjct: 576 SQSKHGENLQNMIENNKDISNKLNQLTAENAKLNSILQNYEKLKQSNSQLQNDYTALQNN 635 Query: 379 ASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXX 438 +++++ SQL ++ + D + K ++++K+ + N+ L+ + + + D Sbjct: 636 NNQLQNNISQLKAKIESADANSKNLSDQLSKM----RDQNEYLIKQNHQL---DNNISVL 688 Query: 439 XXXXXGKDTLIAQL--QLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDV 496 KD L L QL Q+ N + +N + ++ Q KQ E+KD+ Sbjct: 689 ESKLQEKDNLYKNLSEQLSKQKSQ----------NDDFLNRTSSLENQ-KQNYEKELKDL 737 Query: 497 NVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKL-------KQMQKTIDNFSK 549 KD +E L + + ND++ + NM KS+ + KL K ++ + N S Sbjct: 738 --KDKLEDLNKQNKALKNENDKMVTSLHNMETAKSSLEGKLEISDNMVKSLKDQLSNSSS 795 Query: 550 VSDSNKEIVRLTE----ELHHLSQKVAELEEEKGNLQLHLVDYDS-GRMIESDVYKKMIE 604 +S SNK++ L E E L++K+A L+++ L++ L + ++ G ++++ E Sbjct: 796 ISQSNKQLQDLYENERKETKALNEKMAALKQQMSLLEVKLHNTEAEGEKMKNENLMLKSE 855 Query: 605 MENLAETRLKAISLLESQKFDLVQ---ELHILQQKYDEV-------EDKLADISQLQSDQ 654 + L K S +E + DL + +L L+ ++++ + K+AD ++L+++ Sbjct: 856 NDKLKSDSDKTASQVEKLEKDLKKSKKDLSQLESDFEKISAENESLQKKIADKNKLKNET 915 Query: 655 -----VCSEIKSVHL--EEQIDALSASKKELA------------LVIENLKLDKE--QLY 693 + + K+ + +E I+ L KK++ + +EN L K+ + Sbjct: 916 TEKSTLLEQYKNDNKKKDEIINQLKDKKKKIKQENEQNKNNLQKVTVENTSLQKDLQKSQ 975 Query: 694 GTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAE--KISELLAKINHEEQSKIQTQF 751 ++ +ND + N LQ EN++L L+K+ ++ K+ + K+ ++K Sbjct: 976 NDLQKSQNDLQKSQNDLQKLTTENVNLQKDLQKVQSDLQKLQQEREKLQENMENKNTQMK 1035 Query: 752 GIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQK 811 G KI+ + ++S+ K KS +L++ ++ + L++K +++ + + Q Sbjct: 1036 GDFEKIRAN---YDKLKSDYEKLKSDNNQLQKEA---DENKQKLDKKEEKIQNLKLQIQN 1089 Query: 812 AYSEYTIQEDELVNRLAVLMDHDRVVEKQLLE-IEHENKELQK---KNQILLEENQNLQI 867 + + + + RL ++ + K L E IE +NKE+++ KN+ L NLQ Sbjct: 1090 LQKDQSSMKSSEIQRLQNELEQMKANNKSLKENIEAKNKEIEQNKEKNKALKSNLTNLQN 1149 Query: 868 SLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIED 927 ++++Q NAL K L ++E +++ L+ +L++ + K K + Sbjct: 1150 KINEIQ---NALTGKDKENQLLQNELANKNKEIQKLKDDLEKAKSD-------KNKSQNE 1199 Query: 928 LEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLE 987 + + N+++E + +K+ L ++ L+A++Q+ K E L L K Sbjct: 1200 ITDKLNSKLEKVMAEKEDL-------LKQNANLQAEMQKLKAENEKLK---GILKKKTAY 1249 Query: 988 LIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSY---MSMVS 1044 + D + Q + + + Q E++ L+ ++K+K +++ ++I+N Y + + Sbjct: 1250 INDYYAQTVKLEQKSFGLQ--KEVDSLD-VVKKKFDKLYTSREEIDNLFKEYGILQKLYN 1306 Query: 1045 DY--ESKLAQFTTK---LENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIK 1093 D+ + KL + K +E M + V K+ D K +N E Q ++ ++ +K Sbjct: 1307 DHVDKDKLVPYKGKDIEVEKMPALISEVKKKYED-KLNNFEKQTVLTIYNENVK 1359 Score = 109 bits (261), Expect = 8e-22 Identities = 181/954 (18%), Positives = 404/954 (42%), Gaps = 97/954 (10%) Query: 619 LESQKFDLV-QELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKE 677 L + K D + +++ L+ D ++D + + ++ + LEE+ L+ K + Sbjct: 293 LSNAKLDTISRQIRELRAVADNIQDDVIEANRKIDQNKIQVLTREQLEEENKRLNLEKSQ 352 Query: 678 LALVIENLKLDKEQLYGTIK-DLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELL 736 L L DK +L + L+ K D ++ N+ + + L + +++ A K S L Sbjct: 353 LDSSNNQLNDDKHRLQSLLNITLQKMKGDNPSEDTNFTDDMLSLQRERDELFA-KNSYLE 411 Query: 737 AKINHEE--QSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYS 794 ++ E+ +K+ I++ D I+++ +K I ++E+ E+RR Sbjct: 412 KQLQREKIHSTKLMAASEIESSTVPADKNIDDL------WKMYIAVVKEN----ENRR-- 459 Query: 795 LERKADQLGSYLQEKQKAYSEYTIQED-ELVNRLAVLMDHDRVVEKQLLEIEHENKELQK 853 +++ + + + +Q K ++ ++ D + +++ + + ++ K L++ N EL Sbjct: 460 -DKEREDMETIVQMKNDLENKKQLERDNDELSKTVIKLQNELNANKVLMQ--KINSELGF 516 Query: 854 KNQILLEENQNLQISLSDMQQHYNALVEKAN---RTDLAESESTKYQTQLRDLESNLKRI 910 + + + N +S D ++ E N + D ++++ K + L DL+ +K Sbjct: 517 EKVVKMLNNLTELVSNDDKEELVQLKEENKNLKTKNDKSKAKIEKLKKDLEDLKQEIKES 576 Query: 911 THEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNN 970 +H + + +D+ + N + +L + YEK + +QL+ +NN Sbjct: 577 QSKHGENLQNMIENNKDISNKLNQLTAENAKLNSIL-QNYEKLKQSNSQLQNDYTALQNN 635 Query: 971 IENLNMNVEELNKMNLELID---KHVQKQQTQSPDYTEQYINEINKLN---ALLKQKDEE 1024 L N+ +L K +E D K++ Q ++ D E I + ++L+ ++L+ K +E Sbjct: 636 NNQLQNNISQL-KAKIESADANSKNLSDQLSKMRDQNEYLIKQNHQLDNNISVLESKLQE 694 Query: 1025 IIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQIL 1084 L + ++ S D+ ++ + + +N E+E++ + +L D + N+ L+ Sbjct: 695 KDNLYKNLSEQLSKQKSQNDDFLNRTSSLENQKQNYEKELKDLKDKLEDLNKQNKALK-- 752 Query: 1085 VREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKV 1144 E D + L + K E I + ++ + D +N + Sbjct: 753 -NENDKMVTSLHNMETAKSSLEGKLE--ISDNMVKSLKDQLSN---SSSISQSNKQLQDL 806 Query: 1145 QEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLE 1204 E E +E L E+ A L ++ +++++ NTE G + N+ + LKS+ + Sbjct: 807 YENER--KETKALNEKMAALKQQMS-----LLEVKLHNTEAEGEKMKNENLM--LKSEND 857 Query: 1205 QLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAF 1264 +L +++D S V +L + + K+ L+Q E+DF+K E Sbjct: 858 KLKSDSDKTASQVEKLEKDLKKS------------KKDLSQLESDFEKISAEN------- 898 Query: 1265 ESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILR 1324 ES +++ D E T K +EQ +N + K+E + L++K + + E + Sbjct: 899 ESLQKKIADK-NKLKNETTEKSTLLEQY---KNDNKKKDEIINQLKDKKKKIKQENEQNK 954 Query: 1325 SEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXX 1384 + ++ V DL+ ++Q+ Q + + + EN L+K Sbjct: 955 NNLQKVTVE----NTSLQKDLQKSQNDLQ-KSQNDLQKSQNDLQKLTTENVNLQKD---- 1005 Query: 1385 XXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEY 1444 ++ K+ E +E K++++ + + ++E ++ + Sbjct: 1006 LQKVQSDLQKLQQEREKLQE---NMENKNTQMKGDFEKIRANYDKLKSDYEKLKSDNNQL 1062 Query: 1445 EKRIEDLTYE---KESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSL 1501 +K ++ + KE ++ L+L++ +N ++ K SEI+R++ EL + SL Sbjct: 1063 QKEADENKQKLDKKEEKIQNLKLQI-QNLQKDQSSMKSSEIQRLQ--NELEQMKANNKSL 1119 Query: 1502 NKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQ 1555 + + NK E+ + E AL++ + L ++I +QN + + Q Sbjct: 1120 KENIEAKNK----EIEQNKEKNKALKS---NLTNLQNKINEIQNALTGKDKENQ 1166 Score = 89.4 bits (212), Expect = 7e-16 Identities = 157/834 (18%), Positives = 361/834 (43%), Gaps = 78/834 (9%) Query: 789 EDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHEN 848 + + Y K D + ++E +A ++ IQ+D + + + +V+ ++ ++E EN Sbjct: 288 QKKEYLSNAKLDTISRQIREL-RAVAD-NIQDDVIEANRKIDQNKIQVLTRE--QLEEEN 343 Query: 849 KELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLK 908 K L + L N L +Q N ++K + SE T + + L+ Sbjct: 344 KRLNLEKSQLDSSNNQLNDDKHRLQSLLNITLQKMKGDN--PSEDTNFTDDMLSLQRERD 401 Query: 909 RITHEHQTLIVQKKKE-IEDLEIEFNTQIESA-IRDKKVLNEKYEKNIEYVTQLEAQ--- 963 + ++ L Q ++E I ++ ++IES+ + K +++ ++ I V + E + Sbjct: 402 ELFAKNSYLEKQLQREKIHSTKLMAASEIESSTVPADKNIDDLWKMYIAVVKENENRRDK 461 Query: 964 -------LQEYKNNIEN---LNMNVEELNK----MNLELIDKHVQKQQTQSPDYTEQYIN 1009 + + KN++EN L + +EL+K + EL V Q+ S E+ + Sbjct: 462 EREDMETIVQMKNDLENKKQLERDNDELSKTVIKLQNELNANKVLMQKINSELGFEKVVK 521 Query: 1010 EINKLNALLKQKD-EEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVS 1068 +N L L+ D EE++ L ++ N + + +SK K+E ++++++ + Sbjct: 522 MLNNLTELVSNDDKEELVQLKEENKNLKTK------NDKSK-----AKIEKLKKDLEDLK 570 Query: 1069 KQLLDSK-QHNEELQILVREQDDQIKELKE-TKLTFEMNIPKTEGMIISSTIEPMSDDAN 1126 +++ +S+ +H E LQ ++ D +L + T ++N + + + +D Sbjct: 571 QEIKESQSKHGENLQNMIENNKDISNKLNQLTAENAKLNSILQNYEKLKQSNSQLQNDYT 630 Query: 1127 NVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELT 1186 + LK + E ++ L +Q +K+ + + I Q L+ ++ Sbjct: 631 ALQNNNNQLQNNISQLKAKIESADANSKN-LSDQLSKMRDQNEYL---IKQNHQLDNNIS 686 Query: 1187 GHDVVNQEQINQLKSKLEQLN---TENDNLLSTVAEL---RSSISSAVDQRGFEIAELWK 1240 + QE+ N K+ EQL+ ++ND+ L+ + L + + + ++ +L K Sbjct: 687 VLESKLQEKDNLYKNLSEQLSKQKSQNDDFLNRTSSLENQKQNYEKELKDLKDKLEDLNK 746 Query: 1241 QHLA-QREADFQKTE-HELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNK 1298 Q+ A + E D T H + S+ E K E + V+S + +N + LQ+ Sbjct: 747 QNKALKNENDKMVTSLHNMETAKSSLEGKLEISDNMVKSLKDQLSNSSSISQSNKQLQDL 806 Query: 1299 LQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQS 1358 +++ + + L EK A + Q+ +L ++ + + L++EN Sbjct: 807 YENERKETKALNEKMAALKQQMSLLEVKLHNTEAEGEKMKNENLM--------LKSENDK 858 Query: 1359 YKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQ 1418 K +++ + + LKKS + E+ ++ + +LK+ + Sbjct: 859 LKSDSDKTASQVEKLEKDLKKSKKDLSQLESDFEKISAENESLQKKIADKNKLKN----E 914 Query: 1419 KTHEYTITLTQRND--EFENVRQQLVEYEKRIEDLTYEKESEL---AILRLKMHENANHY 1473 T + T+ +ND + + + QL + +K+I+ + ++ L + + ++ Sbjct: 915 TTEKSTLLEQYKNDNKKKDEIINQLKDKKKKIKQENEQNKNNLQKVTVENTSLQKDLQKS 974 Query: 1474 ETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQ---- 1529 + ++S+ + K +L TE+V+L K + ++ L++ + ++Q +EN+ Sbjct: 975 QNDLQKSQNDLQKSQNDLQKLTTENVNLQKDLQKVQSDLQKLQQEREKLQENMENKNTQM 1034 Query: 1530 --EIEIVTLN-DEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKEL 1580 + E + N D++ + +++ ++++QK A + KQ D++ + N +L Sbjct: 1035 KGDFEKIRANYDKLKSDYEKLKSDNNQLQKE---ADENKQKLDKKEEKIQNLKL 1085 >UniRef50_A0BRG1 Cluster: Chromosome undetermined scaffold_122, whole genome shotgun sequence; n=2; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_122, whole genome shotgun sequence - Paramecium tetraurelia Length = 1949 Score = 150 bits (363), Expect = 4e-34 Identities = 245/1159 (21%), Positives = 531/1159 (45%), Gaps = 104/1159 (8%) Query: 491 DEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKT-IDNFSK 549 + + VN K L++++ ++ +I +L E++ KNM ++ + + + KT I+ + Sbjct: 393 ERLLQVNQK-LMQEIATSTNKIKELQLELEMM-KNMSRISMSMSMIEDPVMKTKIEQLEQ 450 Query: 550 VSDS-NKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENL 608 + K+I L EEL Q + ++ +LQ+ + + R +E ++ K E+ L Sbjct: 451 ENQYLQKKISILEEELSKKKQPKPQKQQPDRDLQIQKLTEANKRYLEENL-KLFEEIRQL 509 Query: 609 AETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQI 668 E + L S K +QE +++ + ++ +++ I L+ ++ +I+ + + Q Sbjct: 510 REKFDYSSVLQNSMKDSQIQE-NVVNHQLEQQIERMQQIHNLEIQKMKKKIEKLTNDLQ- 567 Query: 669 DALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMS 728 DA K+ L+ +N +L +E ++ T + ++N + ++K + N + + + Sbjct: 568 DANQVKKQFEQLIKQNKRLVEENMHLT-EQIKNLADINLSKSFSDNMFNSKIFNSDQYKE 626 Query: 729 AEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVM 788 E+ +L + N E QSK+ Q D + Q++ I+ +E E++KYK++I +E + +V Sbjct: 627 LEQQLVVLKRKNEEIQSKLDIQLQRDTQQQDK---IKQLEQEIAKYKNQIREIEYNNSVS 683 Query: 789 EDRRYSLERKADQL----GSYLQEKQKAYSEYT--IQEDELVN-RLAVLMDHDRVVEKQL 841 + + L+ + D + ++E + +Y +Q+ E +N ++ L + ++++ Sbjct: 684 NEVKL-LQNQIDDYQKAKDNLMRENIQLRDDYATLLQDKEYLNGKIKQLENSIFELKQKQ 742 Query: 842 LEIEHENKELQK-----------KNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAE 890 ++++ EN+ L+ + Q L +N+NL + +Q NA + N+++L+ Sbjct: 743 MQLQEENRTLKLFPQSAERQFSVQIQQLQLQNKNLTEEIVRLQSQQNAFKD-LNQSNLSI 801 Query: 891 SESTK----YQTQLRDLESNLKRITH-EHQTLIVQKKKEIEDLE--IEFNTQIESAIRDK 943 SES Y + L N K + E+Q L ++ + E + E I+F QI++ ++ Sbjct: 802 SESVLGSKIYDAKEYKLLENQKELLFTENQQLKLEIRSEYQKSEDQIKFQEQIKALQNER 861 Query: 944 KVLNEKYEKNIEY----VTQLEAQLQEYKNNIENLNMNVEELNKM-NLELIDKHVQKQQT 998 +LN++ N E + L+ Q+ + ++N++++ + N +D + QKQQ Sbjct: 862 DILNQQLISNKEQHSRQIITLQNQIDKLNQQLQNVSLSESRYRVIINDNKVDDYAQKQQD 921 Query: 999 --QSPDYTEQYINEINKL----NALLKQKDEEIIALNQKIN--NAQVSYMSMVSDYESKL 1050 + + +Q +I KL + ++++ ++ L + N + +V+Y S ES + Sbjct: 922 ILRLENENKQLNVQIQKLQLQYDTEIRRQQTQLSDLQFENNKLSREVTYSKQYS--ESVV 979 Query: 1051 AQFTTKLE--NMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKE--TKLTFE-MN 1105 T K + + E E+ ++ QL D K H +L+++ + ++EL++ +KL E N Sbjct: 980 FNQTEKKQYSSQESEIVQLKNQLAD-KTH--QLKVIQTNSQNSMEELQQVISKLGLENKN 1036 Query: 1106 IPKTEGMI-------ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQ 1158 + + I ++ +E + + N++ K QE++ FI+ V Sbjct: 1037 MNEVHNSIKSRLEAQVNKLVEQLREKDQNINKIQDELRRKEQIAKQQEDDLFIKSNQV-- 1094 Query: 1159 EQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVA 1218 EQ + N L +QL LN EL + + + KS ++ EN L S + Sbjct: 1095 EQLIQQNKGLA------LQLNNLNFELQELRMASLSH-SFSKSHIDVRENENQELQSEIQ 1147 Query: 1219 ELRSSISSAVDQ--RGFEIAELWKQHLA----QREADFQKTEHELRVQLSAF-ESKYEQL 1271 LR+ I + Q + + ++L K QRE K + ++ ++ S F + ++ Q Sbjct: 1148 ILRNQIQTLESQSTKQLDNSKLIKLEDEIVHYQREISLIKNKLQITLEDSEFYKREFTQS 1207 Query: 1272 LDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEK 1331 ++ +E + K E++++ +N+L + + L ++ +D I+ + +I DE Sbjct: 1208 QQQIEKMRKELSQK--QSEKLSTQENELVQIKRTNQQLIQENSDQSITIQNQQQQI-DEL 1264 Query: 1332 VAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXX 1391 L+ E + ++ +Q I+ I E ++Q + Sbjct: 1265 QQDLNEYIESNQTITKLKMQLQLEGEKLQRENQQLIIKIQELSSQKQMGRDQELNELIRK 1324 Query: 1392 XXRVNDAEAK-VLELTHQLELKDSEIYQKTHEYTITLTQ-RNDEFENVRQQLVEYEKRIE 1449 + +AK ++ Q +L D+ + T+ ++Q + DEFE +Y++ ++ Sbjct: 1325 LQSMEQDKAKLIISCEQQQQLIDNL------KSTLEISQNKKDEFEIKLHSTEQYKQELQ 1378 Query: 1450 DLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKI-TESVSLNKQVAEL 1508 E++ ++ L+ + + + +T Q++ ++ K + EL V+I + L +Q+ +L Sbjct: 1379 ISLKEQDQKIKQLQQESYYLSKELDTEQQKHTTQKKK-VNELTVQIQNKDNELQQQINKL 1437 Query: 1509 NKALEEEVAKTNEMQTALENQEIEIVTLNDEITN------LQNMVRASSSKIQKHVSFAS 1562 K LEE++ K ++ + L NQ ++ N++ TN Q + + + K Q H S Sbjct: 1438 -KNLEEQILKKDQQISTLNNQISQLKQENNKYTNEIIPKLNQQIDQETLEKNQLHKSLQE 1496 Query: 1563 DTKQGRDEQLDNTMNKELL 1581 Q + L T K L Sbjct: 1497 QFVQMEQQILSMTREKSPL 1515 Score = 142 bits (345), Expect = 5e-32 Identities = 239/1153 (20%), Positives = 509/1153 (44%), Gaps = 120/1153 (10%) Query: 480 KVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVK-SNHKLKLK 538 K QEQ+K N+ +D+ + LI + QI L ++ID N+ + V S + ++ Sbjct: 849 KFQEQIKALQNE--RDILNQQLISNKEQHSRQIITLQNQIDKLNQQLQNVSLSESRYRVI 906 Query: 539 QMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAEL------EEEKGNLQLHLVDYDSGR 592 +D++++ ++I+RL E L+ ++ +L E + QL + +++ + Sbjct: 907 INDNKVDDYAQ---KQQDILRLENENKQLNVQIQKLQLQYDTEIRRQQTQLSDLQFENNK 963 Query: 593 MIESDVYKKMI-EMENLAETRLKAISLLESQ----KFDLVQELHILQQKYDEVEDKLADI 647 + Y K E +T K S ES+ K L + H L+ ++ + ++ Sbjct: 964 LSREVTYSKQYSESVVFNQTEKKQYSSQESEIVQLKNQLADKTHQLKVIQTNSQNSMEEL 1023 Query: 648 SQLQS---------DQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKD 698 Q+ S ++V + IKS LE Q++ L +E I ++ + + K Sbjct: 1024 QQVISKLGLENKNMNEVHNSIKS-RLEAQVNKLVEQLREKDQNINKIQDELRRKEQIAKQ 1082 Query: 699 LENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHE-EQSKIQTQFG----I 753 E+D N+++ IQ+N L +L ++ E +A ++H +S I + + Sbjct: 1083 QEDDLFIKSNQVEQLIQQNKGLALQLNNLNFELQELRMASLSHSFSKSHIDVRENENQEL 1142 Query: 754 DAKIQERDLYIENIESELSKY--KSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQK 811 ++IQ I+ +ES+ +K S++ +LE+ I V R SL + Q+ L++ + Sbjct: 1143 QSEIQILRNQIQTLESQSTKQLDNSKLIKLEDEI-VHYQREISLIKNKLQIT--LEDSEF 1199 Query: 812 AYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSD 871 E+T Q + + ++ + + ++L E+E ++++ NQ L++EN + I++ + Sbjct: 1200 YKREFT-QSQQQIEKMRKELSQKQ--SEKLSTQENELVQIKRTNQQLIQENSDQSITIQN 1256 Query: 872 MQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIE 931 QQ + L + N + TK + QL+ LE +++ E+Q LI++ ++ ++ Sbjct: 1257 QQQQIDELQQDLNEYIESNQTITKLKMQLQ-LEG--EKLQRENQQLIIKIQELSSQKQMG 1313 Query: 932 FNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDK 991 + ++ IR + + + K I Q + + K+ +E ++ N ++ ++ L ++ Sbjct: 1314 RDQELNELIRKLQSMEQDKAKLIISCEQQQQLIDNLKSTLE-ISQNKKDEFEIKLHSTEQ 1372 Query: 992 HVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLA 1051 + Q+ Q + ++ +KQ +E L+++++ Q + + + K+ Sbjct: 1373 YKQELQISLKEQDQK-----------IKQLQQESYYLSKELDTEQQKHTTQ----KKKVN 1417 Query: 1052 QFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKE--TKLTFEMNIPKT 1109 + T +++N + E+Q+ +L + ++ + + ++QI +LK+ K T E+ IPK Sbjct: 1418 ELTVQIQNKDNELQQQINKLKNLEEQILKKDQQISTLNNQISQLKQENNKYTNEI-IPKL 1476 Query: 1110 EGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQ 1169 I T+E N + VQ E++ + S+ +E+S + Sbjct: 1477 NQQIDQETLEK-----NQLHKSLQEQF-------VQMEQQIL---SMTREKSPLKSKSNS 1521 Query: 1170 ECYTKIIQLETLNTELTGHD-VVNQEQ--INQLKSKLEQLNTENDNLLSTVAELRSSISS 1226 +C K ++LN ++T + ++NQ+ I Q KL+ L +N+ LL + +L + Sbjct: 1522 QC--KPFD-QSLNEKITQQEQIINQKNQIIEQQLEKLKILTQQNNGLLHQINKLNDDLRD 1578 Query: 1227 AVDQ-----RGFEIAELWKQHLAQREADFQKT-EHELRVQLSAFES------KYEQLLDS 1274 D+ R E + K ++ AD +H+ + Q +ES +Y+Q + Sbjct: 1579 LQDKSFSLDRSSETYLINKSFNSKYNADNDLILQHQYQSQ-DIYESDRKRQSQYQQFEQT 1637 Query: 1275 VQSSTQEETNKIVTMEQVTS-LQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVA 1333 +Q S QE + + ++Q+ +Q + D E+ ++N+ + I ++ ++ E+ Sbjct: 1638 LQESVQENKSLKLEIDQLKQFIQQQKNDYEKQIQNMSTSNSLQIQELNTKLEKLSQEEKK 1697 Query: 1334 FXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEEN-------AQLKKSSXXXXX 1386 D E KQ EQS +N E +L++ Sbjct: 1698 HQNMPSQNLRNEYQQQIDRLEEELLRKQGVEQSNQRLNNEIKIQITKVVELQQQLEGLRQ 1757 Query: 1387 XXXXXXXRVNDAEAKVLELTH-QLELKDSEIYQKTHEYTITLTQRNDEF-------ENVR 1438 ++ + E + L +++ DS QK E Q +E + + Sbjct: 1758 QNQQLSNQIKEQEELIRSLQKMKIQNSDSSEAQKEGELNQLTQQLQNETLILKGQNQKYQ 1817 Query: 1439 QQLVEYEKRIEDLTYEKESELAILRLKMHE-NANHYETMQKESEIERVKLIEELNVKITE 1497 QQ+ EY+ +IE L E + + + LK + N N+ +T + E E+++L+++ Sbjct: 1818 QQISEYQSKIETLENEIQKKSQQISLKDSQVNQNNRKTKKLE---EQIQLLQDQLKGQGG 1874 Query: 1498 SVSLNKQ--VAELNKALEEEVAKTNEMQTALE--NQEIEIVTLNDEITNLQNMVRASSSK 1553 V+ NK + +L LE++ + E Q ++ +++I+ +T ++ +N K Sbjct: 1875 LVTQNKDEVIVQLQNELEQKRTEMFEFQKQIKQLDEQIDRLTKSNSALMEENCRLNDQLK 1934 Query: 1554 IQKHVSFASDTKQ 1566 +VS+ S+ Q Sbjct: 1935 DNLNVSYLSNDSQ 1947 Score = 128 bits (308), Expect = 2e-27 Identities = 237/1226 (19%), Positives = 547/1226 (44%), Gaps = 120/1226 (9%) Query: 152 KEKDNALSVLQVKMKIMETTILDLQEKINEK-----DQIIEAKNKATTXXXXXXXXXXXX 206 K KDN + ++++ T+L +E +N K + I E K K Sbjct: 698 KAKDNLMRE-NIQLRDDYATLLQDKEYLNGKIKQLENSIFELKQKQMQLQEENRTLKLFP 756 Query: 207 XXXXXEDTKQ-QMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARF 265 + + Q Q ++Q + E +Q KD+ ++ IS +K+ +A + Sbjct: 757 QSAERQFSVQIQQLQLQNKNLTEEIVRLQSQQNAFKDLNQSNLSISESVLGSKIYDAKEY 816 Query: 266 EISLEHSK--LAQELEQXXXXXXXXXXXXXXLAK--QSIEPSCEEKTEIEEKGSLEIANM 321 ++ LE+ K L E +Q K + I+ E+ + ++ I+N Sbjct: 817 KL-LENQKELLFTENQQLKLEIRSEYQKSEDQIKFQEQIKALQNERDILNQQ---LISNK 872 Query: 322 TELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASK 381 + +++I L++ QI + N++L+N ++ + + + + +K ++ ++ Sbjct: 873 EQHSRQIITLQN---QIDKLNQQLQN-VSLSESRYRVIINDNKVDDYAQKQQDILRLENE 928 Query: 382 MKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLV-DKEYVISEKDTXXXXXXX 440 K Q+ L DT+ + + +++ L+ L++++ K+Y SE Sbjct: 929 NKQLNVQIQKLQLQYDTEIRRQQTQLSDLQFENNKLSREVTYSKQY--SESVVFNQTEKK 986 Query: 441 XXXGKDTLIAQL--QLEHQQHMEGPSLIHVGTNTEDVNEIAK---VQEQLKQELNDEIK- 494 +++ I QL QL + H + + E++ ++ ++ + E+++ IK Sbjct: 987 QYSSQESEIVQLKNQLADKTHQLKVIQTNSQNSMEELQQVISKLGLENKNMNEVHNSIKS 1046 Query: 495 --DVNVKDLIEKLKSAEEQITQLNDE------IDAANKNMIKVKSNHKLKLKQMQKTIDN 546 + V L+E+L+ ++ I ++ DE I ++ + +KSN +L Q K + Sbjct: 1047 RLEAQVNKLVEQLREKDQNINKIQDELRRKEQIAKQQEDDLFIKSNQVEQLIQQNKGLA- 1105 Query: 547 FSKVSDSNKEI--VRLTEELHHLSQKVAELEE-EKGNLQLHL-VDYDSGRMIESDVYK-- 600 ++++ N E+ +R+ H S+ ++ E E LQ + + + + +ES K Sbjct: 1106 -LQLNNLNFELQELRMASLSHSFSKSHIDVRENENQELQSEIQILRNQIQTLESQSTKQL 1164 Query: 601 ---KMIEMENLAETRLKAISLLESQKFDLVQELHILQQKY----DEVEDKLADISQLQSD 653 K+I++E+ + ISL++++ +++ ++++ ++E ++SQ QS+ Sbjct: 1165 DNSKLIKLEDEIVHYQREISLIKNKLQITLEDSEFYKREFTQSQQQIEKMRKELSQKQSE 1224 Query: 654 QVCS-EIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKD-LENDKEDIMNKLQ 711 ++ + E + V ++ L + ++ I+N + ++L + + +E+++ K+Q Sbjct: 1225 KLSTQENELVQIKRTNQQLIQENSDQSITIQNQQQQIDELQQDLNEYIESNQTITKLKMQ 1284 Query: 712 NYIQ------ENMDLTDKLEKMSAEK-------ISELLAKINHEEQSKIQTQFGIDAKIQ 758 ++ EN L K++++S++K ++EL+ K+ EQ K + + + Q Sbjct: 1285 LQLEGEKLQRENQQLIIKIQELSSQKQMGRDQELNELIRKLQSMEQDKAKLIISCEQQQQ 1344 Query: 759 ERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSL---ERKADQLGS---YLQEKQKA 812 D +E +K +L + ++ + SL ++K QL YL ++ Sbjct: 1345 LIDNLKSTLEISQNKKDEFEIKLHSTEQYKQELQISLKEQDQKIKQLQQESYYLSKELDT 1404 Query: 813 YSEYTIQEDELVNRLAV-LMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSD 871 + + + VN L V + + D +++Q+ ++++ +++ KK+Q + N + + Sbjct: 1405 EQQKHTTQKKKVNELTVQIQNKDNELQQQINKLKNLEEQILKKDQQISTLNNQISQLKQE 1464 Query: 872 MQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIE 931 ++ N ++ K N+ + E+ + + L+ ++ E Q L + ++K L+ + Sbjct: 1465 NNKYTNEIIPKLNQQ--IDQETLEKNQLHKSLQEQFVQM--EQQILSMTREKS--PLKSK 1518 Query: 932 FNTQIESAIRDKKVLNEKYEKNIEYVTQ----LEAQLQEYKNNIENLNMNVEELNKMNLE 987 N+Q + + LNEK + + + Q +E QL++ K + N + ++NK+N + Sbjct: 1519 SNSQCKPFDQS---LNEKITQQEQIINQKNQIIEQQLEKLKILTQQNNGLLHQINKLNDD 1575 Query: 988 LIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYE 1047 L D +Q + +E Y+ INK D ++I +Q +Q Y S + Sbjct: 1576 LRD--LQDKSFSLDRSSETYL--INKSFNSKYNADNDLILQHQY--QSQDIYESD-RKRQ 1628 Query: 1048 SKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIP 1107 S+ QF L+ +E + + ++ KQ + ++++D K+++ + + I Sbjct: 1629 SQYQQFEQTLQESVQENKSLKLEIDQLKQ------FIQQQKNDYEKQIQNMSTSNSLQIQ 1682 Query: 1108 KTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTE 1167 + +++ +E +S + ++ EE + + +++ + +LN E Sbjct: 1683 E-----LNTKLEKLSQEEKKHQNMPSQNLRNEYQQQIDRLEEELLRKQGVEQSNQRLNNE 1737 Query: 1168 LQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSA 1227 ++ TK+++L+ +L G NQ+ NQ+K + E + + ++++S SS Sbjct: 1738 IKIQITKVVELQQ---QLEGLRQQNQQLSNQIKEQEELIRSLQK------MKIQNSDSSE 1788 Query: 1228 VDQRGFEIAELWKQHLAQREADFQKTEHE-LRVQLSAFESKYEQLLDSVQSSTQEETNKI 1286 + G E+ +L +Q Q E K +++ + Q+S ++SK E L + +Q +Q+ + K Sbjct: 1789 AQKEG-ELNQLTQQ--LQNETLILKGQNQKYQQQISEYQSKIETLENEIQKKSQQISLK- 1844 Query: 1287 VTMEQVTSLQNKLQDKEEHLRNLQEK 1312 QV K + EE ++ LQ++ Sbjct: 1845 --DSQVNQNNRKTKKLEEQIQLLQDQ 1868 Score = 122 bits (293), Expect = 1e-25 Identities = 234/1142 (20%), Positives = 511/1142 (44%), Gaps = 123/1142 (10%) Query: 485 LKQELNDEIKDVNVKDLIEKLK-SAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKT 543 + Q+ D N +E L+ S +Q Q +D+ +N+N ++V+ N+++ + + Sbjct: 111 ISQQYEINCNDQNWIFSLEYLENSTTQQKIQYSDQCILSNQNQLQVQFNNQIMKFKCKDD 170 Query: 544 IDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMI 603 D F S + + R+ L ++ + +L +++ N Q L + ++++ K ++ Sbjct: 171 KDAFCAFFISMQSLRRV--HLKFIAYNIGKLNQKQVNFQSLL----NAQLLQLINEKSVM 224 Query: 604 EMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVH 663 ++ E + + SQ F ++ I Q K + ++QLQS++ Sbjct: 225 PIKKF-EPIQNNVMMATSQDFRTNNQIQITQLKQE--------VAQLQSEKQ-------K 268 Query: 664 LEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDK 723 L++QID L KEL + ++ ++QL ++ + + N++ + Q DL ++ Sbjct: 269 LQQQIDKLFKENKELEINSKSNTASRDQL----DSMDRLIQSLKNEVYSLKQRETDLMNQ 324 Query: 724 LEKMSAEKISELLAKINHEEQSKIQTQFGIDAKI-QERDLYIE------NIESELSKYK- 775 +++ LA ++S Q+QF + K+ Q +D+ +E ++ EL+KY+ Sbjct: 325 NGRLT-------LALNEKNDKSLSQSQFLDEMKVKQYQDMLLECNNEKVRLQEELNKYQK 377 Query: 776 -SRICRLEESIAVMEDRRYSLERK-ADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDH 833 R ++I ++R + +K ++ + + ++ E + ++ +++ M Sbjct: 378 FGSSSRTSQNIDGEKERLLQVNQKLMQEIATSTNKIKELQLELEMMKNMSRISMSMSMIE 437 Query: 834 DRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESES 893 D V++ ++ ++E EN+ LQKK IL EE LS +Q ++ +R DL + Sbjct: 438 DPVMKTKIEQLEQENQYLQKKISILEEE-------LSKKKQP-KPQKQQPDR-DLQIQKL 488 Query: 894 TKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKN 953 T + R LE NLK I Q +++ + + N+ +S I++ V+N + E+ Sbjct: 489 T--EANKRYLEENLKLFEE-----IRQLREKFDYSSVLQNSMKDSQIQE-NVVNHQLEQQ 540 Query: 954 IEYVTQL-EAQLQEYKNNIENLNMNVEELN--KMNLELIDKHVQKQQTQSPDYTEQYINE 1010 IE + Q+ ++Q+ K IE L ++++ N K E + K ++ ++ TEQ I Sbjct: 541 IERMQQIHNLEIQKMKKKIEKLTNDLQDANQVKKQFEQLIKQNKRLVEENMHLTEQ-IKN 599 Query: 1011 INKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQ 1070 + +N L K + + N KI N SD +L Q L+ EE+Q SK Sbjct: 600 LADIN-LSKSFSDNM--FNSKIFN---------SDQYKELEQQLVVLKRKNEEIQ--SK- 644 Query: 1071 LLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTE-GMIISSTIEPMSDDANNVD 1129 LD + + +Q D+IK+L++ ++ I + E +S+ ++ + + ++ Sbjct: 645 -LDIQLQRD------TQQQDKIKQLEQEIAKYKNQIREIEYNNSVSNEVKLLQNQIDDYQ 697 Query: 1130 XXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHD 1189 L+ + +Q++ L + +L + E K +QL+ N L Sbjct: 698 KAKDNLMRENIQLR-DDYATLLQDKEYLNGKIKQLENSIFELKQKQMQLQEENRTL---K 753 Query: 1190 VVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREAD 1249 + Q Q +++QL +N NL + L+S ++ D ++ + + L + D Sbjct: 754 LFPQSAERQFSVQIQQLQLQNKNLTEEIVRLQSQQNAFKDLNQSNLS-ISESVLGSKIYD 812 Query: 1250 FQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNL 1309 K L Q ++ +QL ++S Q+ ++I EQ+ +LQN+ + L + Sbjct: 813 -AKEYKLLENQKELLFTENQQLKLEIRSEYQKSEDQIKFQEQIKALQNERDILNQQLISN 871 Query: 1310 QEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILN 1369 +E+++ QI L+++I D+ D + ++ + KQ + N Sbjct: 872 KEQHS---RQIITLQNQI-DKLNQQLQNVSLSESRYRVIINDNKVDDYAQKQQDILRLEN 927 Query: 1370 INEE-NAQLKKSSXXXXXXXXXXXXRVNDAEAK----VLELTHQLELKDSEIYQKTH--E 1422 N++ N Q++K +++D + + E+T+ + +S ++ +T + Sbjct: 928 ENKQLNVQIQKLQLQYDTEIRRQQTQLSDLQFENNKLSREVTYSKQYSESVVFNQTEKKQ 987 Query: 1423 YT---ITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANH-YETMQK 1478 Y+ + Q ++ + QL + ++ E + ++ L L+ ++N N + +++ Sbjct: 988 YSSQESEIVQLKNQLADKTHQLKVIQTNSQNSMEELQQVISKLGLE-NKNMNEVHNSIKS 1046 Query: 1479 ESEIERVKLIEEL-----NV-KITESVSLNKQVAELNKALEEEVAKTNEMQTALENQE-- 1530 E + KL+E+L N+ KI + + +Q+A+ + ++ K+N+++ ++ + Sbjct: 1047 RLEAQVNKLVEQLREKDQNINKIQDELRRKEQIAKQQE--DDLFIKSNQVEQLIQQNKGL 1104 Query: 1531 -IEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNK-ELLDAVPRAE 1588 +++ LN E+ L+ M S S + H+ + Q ++ N+ + L++ + Sbjct: 1105 ALQLNNLNFELQELR-MASLSHSFSKSHIDVRENENQELQSEIQILRNQIQTLESQSTKQ 1163 Query: 1589 LD 1590 LD Sbjct: 1164 LD 1165 Score = 119 bits (286), Expect = 8e-25 Identities = 246/1267 (19%), Positives = 526/1267 (41%), Gaps = 97/1267 (7%) Query: 298 QSIEPSCEEKTEIEEKGSLEIANMTELTKKIEL-LEHLNCQIRQTNKELENKLATMGTES 356 Q+I+ E ++ +K EIA T K+++L LE + R + + M T+ Sbjct: 386 QNIDGEKERLLQVNQKLMQEIATSTNKIKELQLELEMMKNMSRISMSMSMIEDPVMKTKI 445 Query: 357 KAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQS 416 + + ++ IS + K P Q D D +I K A + ++ Sbjct: 446 EQLEQENQYLQKKISILEEELSKKKQPKPQKQ------QPDRDLQIQKLTEANKRYLEEN 499 Query: 417 LNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQ--QHMEGPSLIHVGTNTED 474 L L ++ + EK KD+ I + + HQ Q +E IH N E Sbjct: 500 LK--LFEEIRQLREKFDYSSVLQNSM--KDSQIQENVVNHQLEQQIERMQQIH---NLE- 551 Query: 475 VNEIAKVQEQLKQELNDEIKDVN-VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNH 533 I K+++++ ++L ++++D N VK E+L +++ + N + KN+ + + Sbjct: 552 ---IQKMKKKI-EKLTNDLQDANQVKKQFEQLIKQNKRLVEENMHLTEQIKNLADINLSK 607 Query: 534 KLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKG-NLQLHLVDYDSGR 592 I N SD KE L ++L L +K E++ + LQ D + Sbjct: 608 SFSDNMFNSKIFN----SDQYKE---LEQQLVVLKRKNEEIQSKLDIQLQRDTQQQDKIK 660 Query: 593 MIESDV--YKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQL 650 +E ++ YK I + + LL++Q D + L ++ ++ D A + Q Sbjct: 661 QLEQEIAKYKNQIREIEYNNSVSNEVKLLQNQIDDYQKAKDNLMRENIQLRDDYATLLQ- 719 Query: 651 QSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKL----DKEQLYGTIKDLENDKEDI 706 + + +IK LE I L + +L LKL + Q I+ L+ +++ Sbjct: 720 DKEYLNGKIK--QLENSIFELKQKQMQLQEENRTLKLFPQSAERQFSVQIQQLQLQNKNL 777 Query: 707 MNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIEN 766 ++ + D + + S L +KI ++ K+ + Q+ L+ EN Sbjct: 778 TEEIVRLQSQQNAFKDLNQSNLSISESVLGSKIYDAKEYKL-------LENQKELLFTEN 830 Query: 767 IESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNR 826 + +L + +S + E+ I E + +L+ + D L L ++ +S I +++ Sbjct: 831 QQLKL-EIRSEYQKSEDQIKFQEQIK-ALQNERDILNQQLISNKEQHSRQIITLQNQIDK 888 Query: 827 LAVLMDHDRVVEKQLLEIEHENK---ELQKKNQILLEENQN--LQISLSDMQQHYNALVE 881 L + + + E + I ++NK QK+ IL EN+N L + + +Q Y+ + Sbjct: 889 LNQQLQNVSLSESRYRVIINDNKVDDYAQKQQDILRLENENKQLNVQIQKLQLQYDTEIR 948 Query: 882 KANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIR 941 + +T L++ +++ E + E +KK+ E E Q+++ + Sbjct: 949 R-QQTQLSD---LQFENNKLSREVTYSKQYSESVVFNQTEKKQYSSQESEI-VQLKNQLA 1003 Query: 942 DK----KVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMN-VEELNKMNLELIDKHVQKQ 996 DK KV+ + ++E + Q+ ++L +EN NMN V K LE + +Q Sbjct: 1004 DKTHQLKVIQTNSQNSMEELQQVISKL-----GLENKNMNEVHNSIKSRLEAQVNKLVEQ 1058 Query: 997 QTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTK 1056 + + +E+ + + KQ+++++ + ++ Q+ + + F + Sbjct: 1059 LREKDQNINKIQDELRRKEQIAKQQEDDLFIKSNQVE--QLIQQNKGLALQLNNLNFELQ 1116 Query: 1057 LENMEEEMQRVSKQLLDSKQH-NEELQILVREQDDQIK--ELKETKLTFEMNIPKTEGMI 1113 M SK +D +++ N+ELQ ++ +QI+ E + TK + K E I Sbjct: 1117 ELRMASLSHSFSKSHIDVRENENQELQSEIQILRNQIQTLESQSTKQLDNSKLIKLEDEI 1176 Query: 1114 ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYT 1173 + E +S N + +++ + + Q+QS KL+T+ E Sbjct: 1177 VHYQRE-ISLIKNKLQITLEDSEFYKREFTQSQQQIEKMRKELSQKQSEKLSTQENE--- 1232 Query: 1174 KIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGF 1233 ++Q++ N +L N +Q ++++ +Q++ E L+ E +I+ Q Sbjct: 1233 -LVQIKRTNQQLIQE---NSDQSITIQNQQQQID-ELQQDLNEYIESNQTITKLKMQLQL 1287 Query: 1234 EIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVT 1293 E +L +++ ++ + E + Q+ + + +L+ +QS Q++ I++ EQ Sbjct: 1288 EGEKLQREN---QQLIIKIQELSSQKQMGR-DQELNELIRKLQSMEQDKAKLIISCEQQQ 1343 Query: 1294 SLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLR 1353 L + L+ E +N ++++ ++ E + E++ +L Sbjct: 1344 QLIDNLKSTLEISQNKKDEFEIKLHSTEQYKQELQISLKEQDQKIKQLQQESYYLSKELD 1403 Query: 1354 TENQSY----KQMQEQSILNINEEN--AQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTH 1407 TE Q + K++ E ++ N++N Q +++ ++ +L Sbjct: 1404 TEQQKHTTQKKKVNELTVQIQNKDNELQQQINKLKNLEEQILKKDQQISTLNNQISQLKQ 1463 Query: 1408 QLELKDSEIYQKTHEYTITLT-QRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKM 1466 + +EI K ++ T ++N +++++Q V+ E++I +T EK L+ K Sbjct: 1464 ENNKYTNEIIPKLNQQIDQETLEKNQLHKSLQEQFVQMEQQILSMTREKSP----LKSKS 1519 Query: 1467 HENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTAL 1526 + ++ E ++ ++I + N I + + K + + N L ++ K N+ L Sbjct: 1520 NSQCKPFDQSLNEKITQQEQIINQKNQIIEQQLEKLKILTQQNNGLLHQINKLNDDLRDL 1579 Query: 1527 ENQEIEI 1533 +++ + Sbjct: 1580 QDKSFSL 1586 Score = 107 bits (256), Expect = 3e-21 Identities = 203/1038 (19%), Positives = 444/1038 (42%), Gaps = 110/1038 (10%) Query: 213 DTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRIS-SLEEANKLLEAARFEISLEH 271 + KQ ++Q+ + + E + +Q L D++ ++ ++S + + + E+ F + + Sbjct: 928 ENKQLNVQIQKLQLQYDTEIR-RQQTQLSDLQFENNKLSREVTYSKQYSESVVFNQTEKK 986 Query: 272 SKLAQELE-QXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIEL 330 +QE E + + + + S EE ++ K LE NM E+ I+ Sbjct: 987 QYSSQESEIVQLKNQLADKTHQLKVIQTNSQNSMEELQQVISKLGLENKNMNEVHNSIK- 1045 Query: 331 LEHLNCQIRQTNKELENK---LATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWS 387 L Q+ + ++L K + + E + +K+ + KS + ++ Sbjct: 1046 -SRLEAQVNKLVEQLREKDQNINKIQDELRRKEQIAKQQEDDLFIKSNQVEQLIQQNKGL 1104 Query: 388 QLSSETLN---QDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXG 444 L LN Q+ + +K + ++ + E I Sbjct: 1105 ALQLNNLNFELQELRMASLSHSFSKSHIDVRENENQELQSEIQILRNQIQTLESQSTKQL 1164 Query: 445 KDTLIAQLQLEHQQHMEGPSLIH--VGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLI 502 ++ + +L+ E + SLI + ED + Q +Q++ K+++ K Sbjct: 1165 DNSKLIKLEDEIVHYQREISLIKNKLQITLEDSEFYKREFTQSQQQIEKMRKELSQKQS- 1223 Query: 503 EKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTID----NFSKVSDSNKEIV 558 EKL + E ++ Q I N+ +I+ S+ + ++ Q+ ID + ++ +SN+ I Sbjct: 1224 EKLSTQENELVQ----IKRTNQQLIQENSDQSITIQNQQQQIDELQQDLNEYIESNQTIT 1279 Query: 559 RLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMI--ESDVYKKMIEMENLAETRLKAI 616 +L +L +K L+ E L + + + S + + + ++ + + +++++ + + K I Sbjct: 1280 KLKMQLQLEGEK---LQRENQQLIIKIQELSSQKQMGRDQELNELIRKLQSMEQDKAKLI 1336 Query: 617 SLLESQKF---DLVQELHILQQKYDEVEDKL---------ADISQLQSDQVCSEIK--SV 662 E Q+ +L L I Q K DE E KL IS + DQ +++ S Sbjct: 1337 ISCEQQQQLIDNLKSTLEISQNKKDEFEIKLHSTEQYKQELQISLKEQDQKIKQLQQESY 1396 Query: 663 HLEEQIDAL----SASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENM 718 +L +++D + KK++ + ++ +L I L+N +E I+ K Q N Sbjct: 1397 YLSKELDTEQQKHTTQKKKVNELTVQIQNKDNELQQQINKLKNLEEQILKKDQQISTLNN 1456 Query: 719 DLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRI 778 ++ +L++ + + +E++ K+N + + + + +QE+ + +E +++ KS + Sbjct: 1457 QIS-QLKQENNKYTNEIIPKLNQQIDQETLEKNQLHKSLQEQFVQMEQQILSMTREKSPL 1515 Query: 779 CRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVE 838 S D+ SL K Q + +K + I E +L +L +L + + Sbjct: 1516 KSKSNSQCKPFDQ--SLNEKITQQEQIINQKNQ------IIEQQL-EKLKILTQQNNGLL 1566 Query: 839 KQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNA-----LVEKANRTDLAESES 893 Q+ ++ + ++LQ K+ L ++ I+ S YNA L + D+ ES+ Sbjct: 1567 HQINKLNDDLRDLQDKSFSLDRSSETYLINKS-FNSKYNADNDLILQHQYQSQDIYESDR 1625 Query: 894 TKYQTQLRDLESNLKRITHEHQTL---IVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKY 950 K Q+Q + E L+ E+++L I Q K+ I+ + ++ QI++ + ++ Sbjct: 1626 -KRQSQYQQFEQTLQESVQENKSLKLEIDQLKQFIQQQKNDYEKQIQNMSTSNSLQIQEL 1684 Query: 951 EKNIEYVTQLEAQLQ---------EYKNNIENLN------MNVEELN-KMNLEL---IDK 991 +E ++Q E + Q EY+ I+ L VE+ N ++N E+ I K Sbjct: 1685 NTKLEKLSQEEKKHQNMPSQNLRNEYQQQIDRLEEELLRKQGVEQSNQRLNNEIKIQITK 1744 Query: 992 HVQKQQTQSP--DYTEQYINEINKLNALLK---------------QKDEEIIALNQKINN 1034 V+ QQ +Q N+I + L++ QK+ E+ L Q++ N Sbjct: 1745 VVELQQQLEGLRQQNQQLSNQIKEQEELIRSLQKMKIQNSDSSEAQKEGELNQLTQQLQN 1804 Query: 1035 AQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKE 1094 + Y+ +++++ +K+E +E E+Q+ S+Q+ S + ++ V + + + K+ Sbjct: 1805 ETLILKGQNQKYQQQISEYQSKIETLENEIQKKSQQI--SLKDSQ-----VNQNNRKTKK 1857 Query: 1095 LKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEE--EEFIQ 1152 L+E + + G++ + E + N ++ +K +E + + Sbjct: 1858 LEEQIQLLQDQLKGQGGLVTQNKDEVIVQLQNELEQKRTEMFEFQKQIKQLDEQIDRLTK 1917 Query: 1153 ERSVLQEQSAKLNTELQE 1170 S L E++ +LN +L++ Sbjct: 1918 SNSALMEENCRLNDQLKD 1935 >UniRef50_Q4RQ56 Cluster: Chromosome 17 SCAF15006, whole genome shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 17 SCAF15006, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1962 Score = 149 bits (362), Expect = 5e-34 Identities = 299/1535 (19%), Positives = 629/1535 (40%), Gaps = 135/1535 (8%) Query: 140 QLGDVTHLSNTIKEKDNALSVLQVKMKIMETT------ILDLQEKINE----KDQIIEAK 189 QLGD +L + E+D + + + K ++ ET + L+ ++ + K++I E K Sbjct: 315 QLGDAKNLIEQL-EQDKGMVIAETKRQMHETLEMKEDEVAQLRSRLQQVTALKEEIQEQK 373 Query: 190 NKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEK---QRLLKDIESK 246 KA E KQ +++E +E ++E+ Q++L ++ + Sbjct: 374 EKAEKSAFEELERALGVAQRAEEARKQLQVQLEEQVKEVERASEEERKSLQQVLTRVKQE 433 Query: 247 DVRI--SSLEEANKLLEAARFE--ISLEH---SKLAQELEQXXXXXXXXXXXXXXLAKQS 299 V I S EE LE E ++ E +++ + +EQ A + Sbjct: 434 VVTIMKKSSEETVANLEKLHSEALVAKEEEMSARMDKAVEQCREEFAQLAKEREQQASLA 493 Query: 300 IEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTE-SKA 358 +E + +KT + + I EL ++E + ++ T +++ + + M E S Sbjct: 494 LEDAELQKTALRTEADNRIK---ELQFELEAAKTRILELESTQEKISQEESKMSHEFSGQ 550 Query: 359 VSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKL----EMVI 414 V K IS ++ K + + + K+ ++ E+ KL ++ + Sbjct: 551 VVELKDKHQEQISALEDKHQEQLEKHTDTLIKQHNAALEELKEKHREELEKLLRDTDVQL 610 Query: 415 QSLNKDLVDK-----EYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVG 469 Q ++L K E + +E D K L+ Q L + H Sbjct: 611 QGRVEELTQKAAEKMEVMQAELDRVSTELSEALNTKQ-LLEQKVLAAEDACRLAREEH-D 668 Query: 470 TNTEDVNEIAKVQ-EQLKQELNDEI--KDVNVKDLIEKLKSAEEQITQLNDEIDAANKNM 526 ++ E K++ +KQE + + + +K+ + LK E + + +E+ A K + Sbjct: 669 KKFQEWEEKHKLELTNIKQEHEESLGGMEKTLKEEVNALKIVEGERQKEIEELTAREKTL 728 Query: 527 IKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLV 586 I+ K+K+K++++ + S+ N+ + EL +S+K+ + E++ +L+ H + Sbjct: 729 IEESHELKVKVKELEELQQSLSQSLQENERLKDSNAELSKISEKLEQCEKDYTDLE-HQL 787 Query: 587 DYDSGRMIESDVYKKMIEMEN-LAETRLKAISLLESQKFDL-VQELHILQQKYDEVEDKL 644 + E D K + E++N L + R + + +S L +E K E+K Sbjct: 788 NAAKNGCQEKD--KLLEELQNQLHQNRTELLEQEKSFTAQLNTKEEEKTSLKKQLEEEKA 845 Query: 645 ADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIK-DLENDK 703 A +LQS E K LE ++D K++ E+ K + T+K +LE Sbjct: 846 AHEKKLQSTVSGMEAKVKALETKLDKFKQKAKDMH---ESAKKKLQTQEETMKMELEKKD 902 Query: 704 EDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLY 763 ++I K Q ++ +++ K + + ++EL A NH+E+ + K++E + Sbjct: 903 KEIHLKEQQIQEKIIEMAQKSSEGLSSAVTELQA--NHKEELE---------KLRESHQH 951 Query: 764 -IENIESELS-KYKSRICRLEESIA-VMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQE 820 +EN+E + K + + L E + ++++ + LE + QL +E ++ SE + Sbjct: 952 EVENLEHRWNEKLRQQEEELSEKHSNALQEKMHELEEVSQQLSRSKEETEQVSSESKGLK 1011 Query: 821 DELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALV 880 ++L R + + ++++L E + + L + +L E+ ++++ +L+ AL Sbjct: 1012 EDLAIRDTTV----QKLQEELNEAAVKLESLSRAELLLKEQMESVERNLN------QALS 1061 Query: 881 EKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAI 940 E+ + D S + ++ +L+ L LK+ + + L + KE +DL+ T+ ES + Sbjct: 1062 ERNSLQDQLTSANRDHEEKLKSLSHELKKAEEQIKLLQGVRSKESKDLK----TKSESVV 1117 Query: 941 RDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQS 1000 + + VLN K E L Q +E KN +L+ ++N +E + Q+++ + Sbjct: 1118 QLQAVLNSKEELICTLEENLRQQAEENKNLCISLDQLTAQVN-AQMEHVTALTQEKENHA 1176 Query: 1001 PDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENM 1060 +E+ + I +L+ + E + A I N + + + ES + T + + Sbjct: 1177 LSLSEK-VQNIQELSEANRSITESVKANESHITNLESIISDLKTQLESSTNEKETTVSLL 1235 Query: 1061 EEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIIS--STI 1118 ++ +Q + + E+ + E+ D ++ + +++G I S + + Sbjct: 1236 MQQYAEEKQQAAGTIERLEQERKSALEEADVLRSSLSDHQNQAERLAQSDGTIASLQARL 1295 Query: 1119 EPMSDD--ANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKII 1176 E + + N D + E ++ + E+ ++ + L +EL C ++ Sbjct: 1296 EELQREICEKNEDVQRLTASIDDQSISKSEMDQVLSEK---DQKVSGLTSELDRCLGRLG 1352 Query: 1177 QLE------TLNTELTGHDVVN-----QEQINQLKSKLEQLNTENDNLLSTVAELRSSIS 1225 +LE T E D+ + + L +L+Q E+ + E+ +S Sbjct: 1353 ELEEQLALKTRECEQVAADLQQERSAWEREKKVLAEELQQTQVEHSQSSNLEQEMGERLS 1412 Query: 1226 SAVDQRGFEIAELWKQHLAQREADFQKTEHEL-RVQLSAFESKYEQLLDSVQSSTQEETN 1284 S + + W++ L +FQK + EL R + + + E+L V E Sbjct: 1413 SLREDN-----QKWQRQLESEREEFQKIKDELIREKEESLRTAEEKLSAEVGRKVSELKK 1467 Query: 1285 KI-VTMEQV-TSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIE--DEKV-AFXXXXX 1339 K + Q+ L ++L++KE+ + LQ +V N + E +EK+ Sbjct: 1468 KAEQKISQIRKQLLSQLEEKEQTMATLQASLEEVKNSETAQKQHTEALEEKIRTSEEALA 1527 Query: 1340 XXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAE 1399 +L ++ + K+ + + NEE L + + D E Sbjct: 1528 RLKEEQEKQLEELLSKEKHEKEKSLEDLRKANEEKLSLLERETERAEELKQTQSSLRDIE 1587 Query: 1400 AKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESEL 1459 A+ E Q E + + + + +E + QL ++ + I L ++E Sbjct: 1588 ARFKETLEQNE-----------KLQVEVNRLKEEIQEKESQLCQHGETIRQLQLRSDAEA 1636 Query: 1460 AILRLKMHEN----ANHYETMQKES---EIERVKLIEELNVK---ITESVSLNKQVAELN 1509 A+ R + + ANH ++++ E + KL++ N K + + L K + L Sbjct: 1637 AVERSSVQQAGSAVANHAPGEEEDADSVECLKSKLMQMKNEKDKIHKDFIRLQKDMRSLR 1696 Query: 1510 KALEE--EVAKTNEMQTALE--NQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTK 1565 K E+ E K M+ + + E+E V + Q + +S + K K Sbjct: 1697 KEHEQDLEFLKKELMEESEQKLKGELEDVQMKHNSAIKQLLREFNSKEALKDTEIDLAVK 1756 Query: 1566 QGRDEQLDNTMNKELLDAVPRAELDLAMYMLHQRD 1600 + ++ + EL+D + R E+ ++ Q+D Sbjct: 1757 EAIEKA--QVVEAELMD-IHRDEVSQLKQLIAQKD 1788 Score = 128 bits (310), Expect = 9e-28 Identities = 238/1222 (19%), Positives = 509/1222 (41%), Gaps = 89/1222 (7%) Query: 143 DVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXX 202 ++ +S + E N +L+ K+ E +E+ ++K Q E K+K Sbjct: 631 ELDRVSTELSEALNTKQLLEQKVLAAEDACRLAREEHDKKFQEWEEKHKLELTNIKQEHE 690 Query: 203 XXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQR-LLKDIESKDVRISSLEE-----A 256 + K+ E E E +++ L+++ V++ LEE + Sbjct: 691 ESLGGMEKTLKEEVNALKIVEGERQKEIEELTAREKTLIEESHELKVKVKELEELQQSLS 750 Query: 257 NKLLEAARFEIS-LEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGS 315 L E R + S E SK++++LEQ AK C+EK ++ E Sbjct: 751 QSLQENERLKDSNAELSKISEKLEQCEKDYTDLEHQLNA-AKNG----CQEKDKLLE--- 802 Query: 316 LEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSG 375 E+ N + ELLE Q N + E K + + ++ KK +S Sbjct: 803 -ELQNQLH-QNRTELLEQEKSFTAQLNTKEEEKTSLKKQLEEEKAAHEKKLQSTVSGMEA 860 Query: 376 RNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXX 435 + A + K + ++ +++ KK+ E ++M ++ +K++ KE I EK Sbjct: 861 KVKALETKLDKFKQKAKDMHESAKKKLQTQE-ETMKMELEKKDKEIHLKEQQIQEK--II 917 Query: 436 XXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKD 495 G + + +LQ H++ +E H E N + E+L+Q+ +E+ + Sbjct: 918 EMAQKSSEGLSSAVTELQANHKEELEKLRESH---QHEVENLEHRWNEKLRQQ-EEELSE 973 Query: 496 VNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNK 555 + L EK+ EE QL+ +K + S+ LK+ D + V + Sbjct: 974 KHSNALQEKMHELEEVSQQLS-----RSKEETEQVSSESKGLKEDLAIRD--TTVQKLQE 1026 Query: 556 EIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKA 615 E+ +L LS+ L+E+ +++ +L S R + + ++ E +LK+ Sbjct: 1027 ELNEAAVKLESLSRAELLLKEQMESVERNLNQALSER---NSLQDQLTSANRDHEEKLKS 1083 Query: 616 ISLLESQKFDLVQELHILQQKYD-EVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSAS 674 +S + + ++ L ++ K +++ K + QLQ+ E LEE + + Sbjct: 1084 LSHELKKAEEQIKLLQGVRSKESKDLKTKSESVVQLQAVLNSKEELICTLEENLRQQAEE 1143 Query: 675 KKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISE 734 K L + ++ L + L +KE+ L +Q +L++ ++ E + Sbjct: 1144 NKNLCISLDQLTAQVNAQMEHVTALTQEKENHALSLSEKVQNIQELSEANRSIT-ESVKA 1202 Query: 735 LLAKINHEEQ--SKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRR 792 + I + E S ++TQ +++ E++ + + + ++ K + E + ++R+ Sbjct: 1203 NESHITNLESIISDLKTQ--LESSTNEKETTVSLLMQQYAEEKQQAAGTIERLE--QERK 1258 Query: 793 YSLERKADQLGSYLQEKQK-----AYSEYTIQ--EDELVNRLAVLMDHDRVVEKQLLEIE 845 +LE +AD L S L + Q A S+ TI + L + + + V++ I+ Sbjct: 1259 SALE-EADVLRSSLSDHQNQAERLAQSDGTIASLQARLEELQREICEKNEDVQRLTASID 1317 Query: 846 HENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLES 905 ++ + +Q+L E++Q + S++ + L E + L E + L+ Sbjct: 1318 DQSISKSEMDQVLSEKDQKVSGLTSELDRCLGRLGELEEQLALKTRECEQVAADLQQ--- 1374 Query: 906 NLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQ 965 +R E + ++ ++ + +E ++ +E + ++ L+ E N ++ QLE++ + Sbjct: 1375 --ERSAWEREKKVLAEELQQTQVEHSQSSNLEQEMGER--LSSLREDNQKWQRQLESERE 1430 Query: 966 EYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINK-LNALLKQKDEE 1024 E++ + L EE + E + V ++ ++ EQ I++I K L + L++K++ Sbjct: 1431 EFQKIKDELIREKEESLRTAEEKLSAEVGRKVSELKKKAEQKISQIRKQLLSQLEEKEQT 1490 Query: 1025 IIALN---QKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEE- 1080 + L +++ N++ + E K+ L ++EE ++ ++LL ++H +E Sbjct: 1491 MATLQASLEEVKNSETAQKQHTEALEEKIRTSEEALARLKEEQEKQLEELLSKEKHEKEK 1550 Query: 1081 -LQILVREQDDQIKEL-KETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXX 1138 L+ L + ++++ L +ET+ E+ ++ I + + + + Sbjct: 1551 SLEDLRKANEEKLSLLERETERAEELKQTQSSLRDIEARFKETLEQNEKLQVEVNRLKE- 1609 Query: 1139 XXXLKVQEEE-EFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQIN 1197 ++QE+E + Q +++ + + E + + Q + + + + + Sbjct: 1610 ----EIQEKESQLCQHGETIRQLQLRSDAEAAVERSSVQQAGSAVANHAPGEEEDADSVE 1665 Query: 1198 QLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREA-------DF 1250 LKSKL Q+ E D + L+ + S + ++ L K+ + + E D Sbjct: 1666 CLKSKLMQMKNEKDKIHKDFIRLQKDMRSLRKEHEQDLEFLKKELMEESEQKLKGELEDV 1725 Query: 1251 Q-KTEHELRVQLSAFESKYEQLLDS-VQSSTQEETNKIVTME---------QVTSLQNKL 1299 Q K ++ L F SK E L D+ + + +E K +E +V+ L+ + Sbjct: 1726 QMKHNSAIKQLLREFNSK-EALKDTEIDLAVKEAIEKAQVVEAELMDIHRDEVSQLKQLI 1784 Query: 1300 QDKEEHLRNLQEKYADVINQIE 1321 K+E L+ +KY VI E Sbjct: 1785 AQKDEELQKNVQKYEQVIQSRE 1806 Score = 110 bits (265), Expect = 3e-22 Identities = 172/887 (19%), Positives = 385/887 (43%), Gaps = 83/887 (9%) Query: 697 KDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAK 756 KD E + + ++ +L + L+ + ++ ++ ++Q+K Q DA Sbjct: 117 KDKEKTQVILSQSQDKSLRRIGELREVLKSLLNVAVAWGQKELQMDQQAKKHLQEEFDAA 176 Query: 757 IQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEY 816 ++E+D I ++++++ K R+ + + A +E E A+ +KQ E Sbjct: 177 LEEKDQMITVLQTQVALLKKRMKGVSDGAAPLEGDVNQAENAAESSPQSPSKKQGEEPEA 236 Query: 817 TIQE--DELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQ 874 T E + + L + E L + + + ++++ L EN+ LQ L + Q Sbjct: 237 TEGEGNSDPAKDMEALQKRVKRQENLLQKCKEIMRTHKERSAQLSTENETLQEQLQERLQ 296 Query: 875 HYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEI-EDLEIEFN 933 +EK +L +E TK TQL D ++ ++++ + +I + K+++ E LE++ + Sbjct: 297 E----LEKIK--ELHTTEKTKLITQLGDAKNLIEQLEQDKGMVIAETKRQMHETLEMKED 350 Query: 934 --TQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDK 991 Q+ S ++ L E+ ++ E + + E + + ++ LE K Sbjct: 351 EVAQLRSRLQQVTALKEEIQEQKEKAEKSAFEELERALGVAQRAEEARKQLQVQLEEQVK 410 Query: 992 HVQKQQTQSPDYTEQYINEI-NKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKL 1050 V++ + +Q + + ++ ++K+ EE +A +K+++ ++V+ E Sbjct: 411 EVERASEEERKSLQQVLTRVKQEVVTIMKKSSEETVANLEKLHSE-----ALVAKEEEMS 465 Query: 1051 AQFTTKLENMEEEMQRVSK---QLLDSKQHNEELQ--ILVREQDDQIKELKETKLTFEMN 1105 A+ +E EE +++K Q + ELQ L E D++IKEL+ FE+ Sbjct: 466 ARMDKAVEQCREEFAQLAKEREQQASLALEDAELQKTALRTEADNRIKELQ-----FELE 520 Query: 1106 IPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAK-L 1164 KT + + ST E +S + + + LK + +E+ QEQ K Sbjct: 521 AAKTRILELESTQEKISQEESKM---SHEFSGQVVELKDKHQEQISALEDKHQEQLEKHT 577 Query: 1165 NTELQECYTKIIQL-----ETLNTELTGHDVVNQEQINQL----KSKLEQLNTENDNLLS 1215 +T +++ + +L E L L DV Q ++ +L K+E + E D + + Sbjct: 578 DTLIKQHNAALEELKEKHREELEKLLRDTDVQLQGRVEELTQKAAEKMEVMQAELDRVST 637 Query: 1216 TVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSV 1275 ++E ++ ++Q+ + + + + FQ+ E + +++L+ + ++E+ L + Sbjct: 638 ELSEALNT-KQLLEQKVLAAEDACRLAREEHDKKFQEWEEKHKLELTNIKQEHEESLGGM 696 Query: 1276 QSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFX 1335 + + +EE N + +E + Q + E L ++ + +++++ E+E+ + + Sbjct: 697 EKTLKEEVNALKIVE------GERQKEIEELTAREKTLIEESHELKVKVKELEELQQSLS 750 Query: 1336 XXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRV 1395 EN+ K + + I+E+ Q +K Sbjct: 751 QSL---------------QENERLKDSNAE-LSKISEKLEQCEKDYTDLEHQLNAAKNGC 794 Query: 1396 NDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVE----YEKRIEDL 1451 + + + EL +QL +E+ ++ +T L + +E ++++QL E +EK+++ Sbjct: 795 QEKDKLLEELQNQLHQNRTELLEQEKSFTAQLNTKEEEKTSLKKQLEEEKAAHEKKLQST 854 Query: 1452 TYEKESELAILRLK----------MHENA-NHYETMQKESEIERVKLIEELNVKITESVS 1500 E+++ L K MHE+A +T ++ ++E K +E+++K E Sbjct: 855 VSGMEAKVKALETKLDKFKQKAKDMHESAKKKLQTQEETMKMELEKKDKEIHLK--EQQI 912 Query: 1501 LNKQVAELNKALEEEVAKTNEMQTALENQEIEIV--TLNDEITNLQN 1545 K + K+ E + E+Q A +E+E + + E+ NL++ Sbjct: 913 QEKIIEMAQKSSEGLSSAVTELQ-ANHKEELEKLRESHQHEVENLEH 958 Score = 103 bits (248), Expect = 3e-20 Identities = 214/1043 (20%), Positives = 437/1043 (41%), Gaps = 100/1043 (9%) Query: 550 VSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLA 609 +S S + +R EL + + + + G +L + D + + ++ + + E + + Sbjct: 126 LSQSQDKSLRRIGELREVLKSLLNVAVAWGQKELQM-DQQAKKHLQEEFDAALEEKDQMI 184 Query: 610 ETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQID 669 ++LL+ + + L+ ++ E+ Q S + E ++ E D Sbjct: 185 TVLQTQVALLKKRMKGVSDGAAPLEGDVNQAENAAESSPQSPSKKQGEEPEATEGEGNSD 244 Query: 670 A---LSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEK 726 + A +K + ENL +++ T K+ LQ +QE +L++ Sbjct: 245 PAKDMEALQKRVKRQ-ENLLQKCKEIMRTHKERSAQLSTENETLQEQLQE------RLQE 297 Query: 727 MSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICR-LEESI 785 + EKI EL + E++K+ TQ G DAK IE +E + + R + E++ Sbjct: 298 L--EKIKEL----HTTEKTKLITQLG-DAK-----NLIEQLEQDKGMVIAETKRQMHETL 345 Query: 786 AVMEDRRYSLERKADQLGSYLQE--KQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLE 843 + ED L + Q+ + +E +QK +E + E EL L V + ++ ++ Sbjct: 346 EMKEDEVAQLRSRLQQVTALKEEIQEQKEKAEKSAFE-ELERALGVAQRAEEARKQLQVQ 404 Query: 844 IEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESE---STKYQTQL 900 +E + KE+++ ++ EE ++LQ L+ ++Q +++K++ +A E S + Sbjct: 405 LEEQVKEVERASE---EERKSLQQVLTRVKQEVVTIMKKSSEETVANLEKLHSEALVAKE 461 Query: 901 RDLESNLKRITHEHQTLIVQKKKEIE---DLEIEFNTQIESAIR---DKKVLNEKYEKNI 954 ++ + + + + + Q KE E L +E ++A+R D ++ ++E Sbjct: 462 EEMSARMDKAVEQCREEFAQLAKEREQQASLALEDAELQKTALRTEADNRIKELQFELEA 521 Query: 955 EYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQ-------KQQTQSPDYTEQY 1007 LE + + K + E M+ E + +EL DKH + K Q Q +T+ Sbjct: 522 AKTRILELESTQEKISQEESKMS-HEFSGQVVELKDKHQEQISALEDKHQEQLEKHTDTL 580 Query: 1008 INEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRV 1067 I + N LK+K E L + + + V V + K A+ K+E M+ E+ RV Sbjct: 581 IKQHNAALEELKEKHRE--ELEKLLRDTDVQLQGRVEELTQKAAE---KMEVMQAELDRV 635 Query: 1068 SKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANN 1127 S +L ++ + L+ V +D + +E + + E + + Sbjct: 636 STELSEALNTKQLLEQKVLAAEDACRLARE---EHDKKFQEWEEKHKLELTNIKQEHEES 692 Query: 1128 VDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTG 1187 + LK+ E E + ++E +A+ T ++E + EL Sbjct: 693 LGGMEKTLKEEVNALKIVEGE----RQKEIEELTAREKTLIEESH-----------ELK- 736 Query: 1188 HDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQRE 1247 V +++ +L+ L Q EN+ L + AEL S IS ++Q + +L Q A + Sbjct: 737 ---VKVKELEELQQSLSQSLQENERLKDSNAEL-SKISEKLEQCEKDYTDLEHQLNAAKN 792 Query: 1248 ADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKL-QDKEEHL 1306 +K + +Q +++ E LL+ +S T + K E+ TSL+ +L ++K H Sbjct: 793 GCQEKDKLLEELQNQLHQNRTE-LLEQEKSFTAQLNTK---EEEKTSLKKQLEEEKAAHE 848 Query: 1307 RNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQS 1366 + LQ + + +++ L ++++ K ++ E + + Sbjct: 849 KKLQSTVSGMEAKVKALETKLDKFKQKAKDMHESAKKKLQTQEETMKMELEKKDKEIHLK 908 Query: 1367 ILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSE------IYQKT 1420 I E+ ++ + S + E + L +HQ E+++ E + Q+ Sbjct: 909 EQQIQEKIIEMAQKSSEGLSSAVTELQANHKEELEKLRESHQHEVENLEHRWNEKLRQQE 968 Query: 1421 HE----YTITLTQRNDEFENVRQQLVEYEKRIEDLTYEK---ESELAILRL---KMHENA 1470 E ++ L ++ E E V QQL ++ E ++ E + +LAI K+ E Sbjct: 969 EELSEKHSNALQEKMHELEEVSQQLSRSKEETEQVSSESKGLKEDLAIRDTTVQKLQEEL 1028 Query: 1471 NHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQE 1530 N E K + R +L+ + ++ E +LN+ ++E N ++ + + + L++ Sbjct: 1029 N--EAAVKLESLSRAELLLKEQMESVER-NLNQALSERNSLQDQLTSANRDHEEKLKSLS 1085 Query: 1531 IEIVTLNDEITNLQNMVRASSSK 1553 E+ ++I LQ VR+ SK Sbjct: 1086 HELKKAEEQIKLLQG-VRSKESK 1107 Score = 89.4 bits (212), Expect = 7e-16 Identities = 172/967 (17%), Positives = 396/967 (40%), Gaps = 81/967 (8%) Query: 155 DNALSVLQVKMKIMETTILDLQEKINEKDQIIEAK--NKATTXXXXXXXXXXXXXXXXXE 212 ++A LQ + + M+ + ++I+ K+Q I+ K A E Sbjct: 881 ESAKKKLQTQEETMKMELEKKDKEIHLKEQQIQEKIIEMAQKSSEGLSSAVTELQANHKE 940 Query: 213 DTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESK-----DVRISSLEEANKLLEAARFEI 267 + ++ Q +E W ++ ++ +++ K ++ LEE ++ L ++ E Sbjct: 941 ELEKLRESHQHEVENLEHRWNEKLRQQEEELSEKHSNALQEKMHELEEVSQQLSRSKEET 1000 Query: 268 SLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKK 327 S+ E L + +++ + E+ K +E L + Sbjct: 1001 EQVSSESKGLKEDLAIRDTTVQKLQEELNEAAVKLESLSRAELLLKEQMESVERN-LNQA 1059 Query: 328 IELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSG--RNTASKMKSP 385 + L Q+ N++ E KL ++ E K K + S++S + + + Sbjct: 1060 LSERNSLQDQLTSANRDHEEKLKSLSHELKKAEEQIKLLQGVRSKESKDLKTKSESVVQL 1119 Query: 386 WSQLSSE-----TLNQDTDKKI--NKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXX 438 + L+S+ TL ++ ++ NKN L+ + +N + + EK+ Sbjct: 1120 QAVLNSKEELICTLEENLRQQAEENKNLCISLDQLTAQVNAQMEHVTALTQEKENHALSL 1179 Query: 439 XXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNV 498 L + + S H+ TN E + I+ ++ QL+ N+ K+ V Sbjct: 1180 SEKVQNIQELSEANRSITESVKANES--HI-TNLESI--ISDLKTQLESSTNE--KETTV 1232 Query: 499 KDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIV 558 L+++ ++Q + ++ K+ ++ + L Q + +++ S+ I Sbjct: 1233 SLLMQQYAEEKQQAAGTIERLEQERKSALEEADVLRSSLSDHQNQAE---RLAQSDGTIA 1289 Query: 559 RLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGR----MIESDVYKKMIEMENLAETRLK 614 L L L +++ E E+ L + D + + S+ +K+ + + + L Sbjct: 1290 SLQARLEELQREICEKNEDVQRLTASIDDQSISKSEMDQVLSEKDQKVSGLTSELDRCLG 1349 Query: 615 AISLLESQKFDLVQELHI----LQQKYDEVE-DKLADISQLQSDQVCSEIKSVHLEEQI- 668 + LE Q +E LQQ+ E +K +LQ QV +S +LE+++ Sbjct: 1350 RLGELEEQLALKTRECEQVAADLQQERSAWEREKKVLAEELQQTQV-EHSQSSNLEQEMG 1408 Query: 669 DALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDL-TDKLEKM 727 + LS+ +++ L+ ++E+ +L +KE+ + + + + +L+K Sbjct: 1409 ERLSSLREDNQKWQRQLESEREEFQKIKDELIREKEESLRTAEEKLSAEVGRKVSELKKK 1468 Query: 728 SAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAV 787 + +KIS++ ++ + + K QT + A ++E ++N E+ ++ LEE I Sbjct: 1469 AEQKISQIRKQLLSQLEEKEQTMATLQASLEE----VKNSETAQKQHTEA---LEEKIRT 1521 Query: 788 MEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAV-LMDHDRVVEKQLLEIEH 846 E+ L+ + ++ L K+K E ++++ N + L++ + ++L + + Sbjct: 1522 SEEALARLKEEQEKQLEELLSKEKHEKEKSLEDLRKANEEKLSLLERETERAEELKQTQS 1581 Query: 847 ENKELQKKNQILLEENQNLQISL-----------SDMQQHYNALVEKANRTDLAESESTK 895 ++++ + + LE+N+ LQ+ + S + QH + + R+D + Sbjct: 1582 SLRDIEARFKETLEQNEKLQVEVNRLKEEIQEKESQLCQHGETIRQLQLRSDAEAAVERS 1641 Query: 896 YQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIR---DKKVLNEKYEK 952 Q +N E + K ++ ++ E + + IR D + L +++E+ Sbjct: 1642 SVQQAGSAVANHAPGEEEDADSVECLKSKLMQMKNEKDKIHKDFIRLQKDMRSLRKEHEQ 1701 Query: 953 NIEYVTQ--LEAQLQEYKNNIENLNM--------------NVEELNKMNLELIDKH-VQK 995 ++E++ + +E Q+ K +E++ M + E L ++L K ++K Sbjct: 1702 DLEFLKKELMEESEQKLKGELEDVQMKHNSAIKQLLREFNSKEALKDTEIDLAVKEAIEK 1761 Query: 996 QQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTT 1055 Q + + + +E+++L L+ QKDEE L + + + S + ++ Q Sbjct: 1762 AQVVEAELMDIHRDEVSQLKQLIAQKDEE---LQKNVQKYEQVIQSREQEMGDRVWQVQK 1818 Query: 1056 KLENMEE 1062 +LE ++E Sbjct: 1819 ELEELQE 1825 >UniRef50_UPI0000498399 Cluster: Viral A-type inclusion protein repeat; n=1; Entamoeba histolytica HM-1:IMSS|Rep: Viral A-type inclusion protein repeat - Entamoeba histolytica HM-1:IMSS Length = 1387 Score = 149 bits (361), Expect = 6e-34 Identities = 224/1124 (19%), Positives = 490/1124 (43%), Gaps = 94/1124 (8%) Query: 239 LLKD-IESKDVRISSLEEANKLLEAARFEIS-LEHSKLAQELEQXXXXXXXXXXXXXXLA 296 L+KD IE V ++++ E +++E E +++ + QEL L Sbjct: 280 LVKDKIEKLRVNVANMMEGLEMVEVEEDEFDEMDNDMIIQELNIHKGKIDNMMLEAMELV 339 Query: 297 KQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTES 356 K+ E + E + + + KKIE LE L +++ +E E M Sbjct: 340 KEESSTPIEIRGEDSQALEELRVQIKQKIKKIEELEKLVSVMKEKKEEAEKAEREM--RM 397 Query: 357 KAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKI--NKNEIAKLEMVI 414 K + + G KS + ++K Q+ D +K I NK + E++I Sbjct: 398 KCQNESTLMGIIEEFEKSVKELNDRIKEKNKQID------DYEKTIEENKEDFEAKELII 451 Query: 415 QSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTED 474 Q L +++ +K + T + Q + Q ++ + ++ Sbjct: 452 QQLKDEIIQLTNT-EQKLKEQLEIKEKELQEQTKEVKEQNQQQNIIQKKEQEIIDIKKKN 510 Query: 475 VNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHK 534 I +Q+++++E N+ + +K+L + EE++ ++ + D K + ++ Sbjct: 511 EETIQLIQKEMEKERNE--LSIKIKELENIISGKEEEMNKIKEIHDYKEKEIQRITEKMN 568 Query: 535 LKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMI 594 + + KT +K+ + N E +++ L ++ EEEKG +L L + + + I Sbjct: 569 KETEINNKTQQELNKIKEENNEY---KNQINTLEIEIKTKEEEKGTTELELKE--NQKSI 623 Query: 595 ESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDE-VEDKLADISQLQSD 653 + K++ E E + + +K + E QK +++E + ++++ E VE+ + + +S+ Sbjct: 624 QE--LKELKEQERINK-EIKEKEVKELQK--IIEEWKVKEKEWKEQVEENQKE--KEESE 676 Query: 654 QVCSEIKSV--HLEEQIDALSAS----KKELALVIENLKLDKEQLYGTIKDLENDKEDIM 707 + +++K + EE++ L+ KE ++ E +K + E++ G I+ L+ + Sbjct: 677 ENKNQMKRIIEKKEEEVKGLNQEIDKINKENEIMKEKMK-ELERIKGEIEVLKIKETGDS 735 Query: 708 NKLQNYIQENMDLTD--KLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIE 765 N+ + I+E + K + K +E+ K +EE ++ + + D + +++++ Sbjct: 736 NEYEKMIEELKKQIEIIKNDNEKERKNNEIEQKKKNEEFNQKEEELNNDIEKKKKEIEKL 795 Query: 766 NIESELSKYKSRICRLEESIAVMEDRRYSLERKA--DQLGSYLQEKQKAYSEYTIQEDEL 823 N + E K K+ E + + +L+++ +L S + EK + E +++ Sbjct: 796 NKQIEELKQKNEENTKENIEKQNQINQLNLDKEKIMKELESTIMEKNQIEEERKKEQEIN 855 Query: 824 VNRLA-VLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALV-E 881 ++ ++ D + + I +E KK L + NQ L + ++ N + E Sbjct: 856 EKKINDIITSKDTKINELNKSIIELKEEWNKKENNLNKSNQELTEQIIQKEEIINVTIKE 915 Query: 882 KANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIR 941 N + E K +T++ +L+ +K E+ I + KE E+++ EF QI++ + Sbjct: 916 NENLKKVKEEIEKKTETEINELQRKIK----ENNEQINEINKEKENIQKEFEIQIDNKNK 971 Query: 942 DKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSP 1001 + + EK EK I + ++ + KN +ENL +E N E+I K +K++ Sbjct: 972 EINEIKEKNEKEINEIKIQIEEMNKEKNQLENLKKQLENEN----EIIKKENKKKE---- 1023 Query: 1002 DYTEQYINEINKLNALLKQKDEEIIALNQKINN------AQVSYMSMVSDYESKLAQ-FT 1054 E ++ L+K+ +++I ++ +IN+ ++ + M+ + + + + F Sbjct: 1024 -------EENKEMGYLIKENEKKIESIRNEINSKERELGTKIKLIEMIKNEKDIMEKDFK 1076 Query: 1055 TKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMII 1114 +++N E++R+ +D ++ ++ +++++ D+ K+ E K I K I Sbjct: 1077 KEVDNKNIEIKRLQ---IDIEKKKNDITLIIQKNDEDKKKSIEEKKNLNQEIEK-----I 1128 Query: 1115 SSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTK 1174 S + + + K Q E E +Q + + L E+ E K Sbjct: 1129 KSEKNDVQKEKEQILLEKEDLQSDFNKYKTQMENEKLQIKEEHENNITNLQNEINE---K 1185 Query: 1175 IIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFE 1234 I Q + + ++ + +N +Q+++LK +L + E + E++ I A E Sbjct: 1186 INQNDEIKLQI---EQLN-KQLDELKQQLVETQKEKEEETKKYEEVKGQIDGAHQ----E 1237 Query: 1235 IAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTS 1294 + + K+ +++ + K E + +Q + FE+K E+L V+S ET T Sbjct: 1238 VENIKKE--TEQQINQMKKECD-EMQKTTFEAK-EELRVQVESVKMIETKVSTQKVSNTK 1293 Query: 1295 LQNKLQDKE---EHLRN-LQEKYADVINQIEILRSEIEDEKVAF 1334 L+ ++++ E E L+N EK A + + + ED+KV F Sbjct: 1294 LKKRVEELERTIEKLKNERNEKEAFWEKKKMWMIEDEEDKKVLF 1337 Score = 138 bits (335), Expect = 9e-31 Identities = 241/1133 (21%), Positives = 488/1133 (43%), Gaps = 120/1133 (10%) Query: 473 EDVNEIAKVQEQLKQELNDEIKD------VNVKDLIEKLKSAEEQITQLNDEIDAANKNM 526 E + E+ K+ + ++ ++ +KD VNV +++E L+ E + DE D + +M Sbjct: 261 ELIEELEKLMDICRKNTDELVKDKIEKLRVNVANMMEGLEMVEVE----EDEFDEMDNDM 316 Query: 527 IKVKSN-HKLKLKQMQKTIDNFSKVSDSNKEIVR-----LTEELH-HLSQKVAELEEEKG 579 I + N HK K+ M K S +R EEL + QK+ ++EE + Sbjct: 317 IIQELNIHKGKIDNMMLEAMELVKEESSTPIEIRGEDSQALEELRVQIKQKIKKIEELE- 375 Query: 580 NLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHI-LQQKYD 638 LV + E++ ++ + M+ E+ L I + E +K V+EL+ +++K Sbjct: 376 ----KLVSVMKEKKEEAEKAEREMRMKCQNESTLMGI-IEEFEKS--VKELNDRIKEKNK 428 Query: 639 EVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKD 698 +++D I + + D E+ L+++I L+ ++++L E L++ +++L K+ Sbjct: 429 QIDDYEKTIEENKEDFEAKELIIQQLKDEIIQLTNTEQKLK---EQLEIKEKELQEQTKE 485 Query: 699 LENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQ 758 ++ + N +Q QE +D+ K E+ + + I + + K +E KI+ I + + Sbjct: 486 VKEQNQQ-QNIIQKKEQEIIDIKKKNEE-TIQLIQKEMEKERNELSIKIKELENIISGKE 543 Query: 759 ERDLYIENIESELSKYKSRIC-RLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYT 817 E I+ I K RI ++ + + + L + ++ Y + E Sbjct: 544 EEMNKIKEIHDYKEKEIQRITEKMNKETEINNKTQQELNKIKEENNEYKNQINTLEIEIK 603 Query: 818 IQEDELVNRLAVLMDHDRVVE--KQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQH 875 +E+E L ++ + ++ K+L E E NKE+++K ++E Q + ++ Sbjct: 604 TKEEEKGTTELELKENQKSIQELKELKEQERINKEIKEKE---VKELQKIIEEWKVKEKE 660 Query: 876 YNALVEKANRTDLAESESTKYQT---------QLRDLESNLKRITHEHQTLIVQKKKEIE 926 + VE+ N+ + ESE K Q +++ L + +I E++ ++ +K KE+E Sbjct: 661 WKEQVEE-NQKEKEESEENKNQMKRIIEKKEEEVKGLNQEIDKINKENE-IMKEKMKELE 718 Query: 927 DLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVE-ELNKMN 985 ++ E I++ NE YEK IE +L+ Q++ KN+ E N E E K N Sbjct: 719 RIKGEIEVL---KIKETGDSNE-YEKMIE---ELKKQIEIIKNDNEKERKNNEIEQKKKN 771 Query: 986 LELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSD 1045 E K +++ + ++ I ++NK LKQK+EE N + N Q++ +++ + Sbjct: 772 EEFNQK--EEELNNDIEKKKKEIEKLNKQIEELKQKNEENTKENIEKQN-QINQLNLDKE 828 Query: 1046 YESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMN 1105 K + T +N EE +R +Q ++ K+ N+ ++ +D +I EL ++ + + Sbjct: 829 KIMKELESTIMEKNQIEE-ERKKEQEINEKKIND----IITSKDTKINELNKSIIELKEE 883 Query: 1106 IPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSV--LQ----- 1158 K E + S E + KV+EE E E + LQ Sbjct: 884 WNKKENNLNKSNQELTEQIIQKEEIINVTIKENENLKKVKEEIEKKTETEINELQRKIKE 943 Query: 1159 --EQSAKLNTELQECYTKI-IQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLS 1215 EQ ++N E + + IQ++ N E+ N+++IN++K ++E++N E + L + Sbjct: 944 NNEQINEINKEKENIQKEFEIQIDNKNKEINEIKEKNEKEINEIKIQIEEMNKEKNQLEN 1003 Query: 1216 TVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSV 1275 +L + E+ K+ ++E + E+ + E K E + + + Sbjct: 1004 LKKQLENE------------NEIIKKENKKKEEE----NKEMGYLIKENEKKIESIRNEI 1047 Query: 1276 QSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFX 1335 S +E KI +E + + + + +K+ +K D N IEI R +I+ EK Sbjct: 1048 NSKERELGTKIKLIEMIKN-EKDIMEKDF------KKEVDNKN-IEIKRLQIDIEKKKND 1099 Query: 1336 XXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRV 1395 + + K ++E+ N+N+E ++K Sbjct: 1100 ITLIIQ-----------KNDEDKKKSIEEKK--NLNQEIEKIKSEKNDVQKEKEQILLEK 1146 Query: 1396 NDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQ--------RNDEFENVRQQLVEYEKR 1447 D ++ + Q+E + +I ++ HE IT Q +NDE + +QL + Sbjct: 1147 EDLQSDFNKYKTQMENEKLQIKEE-HENNITNLQNEINEKINQNDEIKLQIEQLNKQLDE 1205 Query: 1448 IEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAE 1507 ++ E + E K E + +E E + + +++N E + K E Sbjct: 1206 LKQQLVETQKEKEEETKKYEEVKGQIDGAHQEVENIKKETEQQINQMKKECDEMQKTTFE 1265 Query: 1508 LNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSF 1560 + L +V ++T + Q++ L + L+ + ++ + +F Sbjct: 1266 AKEELRVQVESVKMIETKVSTQKVSNTKLKKRVEELERTIEKLKNERNEKEAF 1318 Score = 138 bits (333), Expect = 2e-30 Identities = 198/1041 (19%), Positives = 464/1041 (44%), Gaps = 72/1041 (6%) Query: 573 ELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHI 632 EL EE L + + ++ +++ + K + + N+ E L+ + + E +FD + I Sbjct: 261 ELIEELEKL-MDICRKNTDELVKDKIEKLRVNVANMMEG-LEMVEV-EEDEFDEMDNDMI 317 Query: 633 LQQKYDEVEDKLADISQLQSDQVCSEIKSVHLE---EQIDALSASKKELALVIENLKLDK 689 +Q+ + D L++ ++ E S +E E AL + ++ I+ ++ + Sbjct: 318 IQEL--NIHKGKIDNMMLEAMELVKEESSTPIEIRGEDSQALEELRVQIKQKIKKIE-EL 374 Query: 690 EQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKM--SAEKISELLAKINHEEQSKI 747 E+L +K+ + + E +++ Q L +E+ S +++++ + + N + Sbjct: 375 EKLVSVMKEKKEEAEKAEREMRMKCQNESTLMGIIEEFEKSVKELNDRIKEKNKQIDDYE 434 Query: 748 QTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKA---DQLGS 804 +T + ++L I+ ++ E+ + + +L+E + + E ++ +Q + Sbjct: 435 KTIEENKEDFEAKELIIQQLKDEIIQLTNTEQKLKEQLEIKEKELQEQTKEVKEQNQQQN 494 Query: 805 YLQEKQKAYSEYTIQEDELVNRLAVLMDHDR-VVEKQLLEIEH----ENKELQKKNQILL 859 +Q+K++ + + +E + + M+ +R + ++ E+E+ + +E+ K +I Sbjct: 495 IIQKKEQEIIDIKKKNEETIQLIQKEMEKERNELSIKIKELENIISGKEEEMNKIKEIHD 554 Query: 860 EENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIV 919 + + +Q M + + + + E+ +Y+ Q+ LE +K E T + Sbjct: 555 YKEKEIQRITEKMNKETEINNKTQQELNKIKEENNEYKNQINTLEIEIKTKEEEKGTTEL 614 Query: 920 QKK---KEIEDL-EIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLN 975 + K K I++L E++ +I I++K+V ++ +K IE + + + +E+K +E N Sbjct: 615 ELKENQKSIQELKELKEQERINKEIKEKEV--KELQKIIE---EWKVKEKEWKEQVEE-N 668 Query: 976 MNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNA 1035 +E ++ N + + ++K++ + ++ I++INK N ++K+K +E+ + +I Sbjct: 669 QKEKEESEENKNQMKRIIEKKEEEVKGLNQE-IDKINKENEIMKEKMKELERIKGEIEVL 727 Query: 1036 QVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQL-LDSKQHNEELQILVREQDDQIKE 1094 ++ ++YE + + ++E ++ + ++ K ++ K+ NEE E ++ I++ Sbjct: 728 KIKETGDSNEYEKMIEELKKQIEIIKNDNEKERKNNEIEQKKKNEEFNQKEEELNNDIEK 787 Query: 1095 LKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLK--VQEEEEFIQ 1152 K+ I + + +T E + + N ++ L+ + E+ + + Sbjct: 788 KKKEIEKLNKQIEELKQKNEENTKENI-EKQNQINQLNLDKEKIMKELESTIMEKNQIEE 846 Query: 1153 ERSVLQE-QSAKLN-------TELQECYTKIIQL-ETLNTELTGHDVVNQEQINQLKSKL 1203 ER QE K+N T++ E II+L E N + + NQE Q+ K Sbjct: 847 ERKKEQEINEKKINDIITSKDTKINELNKSIIELKEEWNKKENNLNKSNQELTEQIIQKE 906 Query: 1204 EQLNT---ENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQ 1260 E +N EN+NL E+ + +++ +I E +Q + + + + + E +Q Sbjct: 907 EIINVTIKENENLKKVKEEIEKKTETEINELQRKIKENNEQ-INEINKEKENIQKEFEIQ 965 Query: 1261 LSAFESKYEQLLDSVQSSTQEETNKI-VTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQ 1319 + ++K +++ + ++ ++E N+I + +E++ +N+L++ ++ L N E I + Sbjct: 966 I---DNKNKEI-NEIKEKNEKEINEIKIQIEEMNKEKNQLENLKKQLENENE-----IIK 1016 Query: 1320 IEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKK 1379 E + E E++++ + + + K + I N E ++K Sbjct: 1017 KENKKKEEENKEMGYLIKENEKKIESIRNEINSKERELGTKIKLIEMIKN---EKDIMEK 1073 Query: 1380 SSXXXXXXXXXXXXRVN-DAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVR 1438 R+ D E K ++T ++ K+ E +K+ E L N E E ++ Sbjct: 1074 DFKKEVDNKNIEIKRLQIDIEKKKNDITLIIQ-KNDEDKKKSIEEKKNL---NQEIEKIK 1129 Query: 1439 QQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITES 1498 + + +K E + EKE + + N +++E E L E+N KI ++ Sbjct: 1130 SEKNDVQKEKEQILLEKEDLQSDFNKYKTQMENEKLQIKEEHENNITNLQNEINEKINQN 1189 Query: 1499 VSLNKQVAELNKALEE------EVAKTNEMQT-ALENQEIEIVTLNDEITNLQNMVRASS 1551 + Q+ +LNK L+E E K E +T E + +I + E+ N++ Sbjct: 1190 DEIKLQIEQLNKQLDELKQQLVETQKEKEEETKKYEEVKGQIDGAHQEVENIKKETEQQI 1249 Query: 1552 SKIQKHVSFASDTKQGRDEQL 1572 ++++K T E+L Sbjct: 1250 NQMKKECDEMQKTTFEAKEEL 1270 Score = 88.6 bits (210), Expect = 1e-15 Identities = 119/595 (20%), Positives = 259/595 (43%), Gaps = 37/595 (6%) Query: 217 QMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQ 276 + K E F E E ++ ++ K+IE + +I L++ N+ E + ++L Sbjct: 766 EQKKKNEEFNQKEEELNNDIEKKKKEIEKLNKQIEELKQKNEENTKENIEKQNQINQLNL 825 Query: 277 ELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNC 336 + E+ + K IE +++ EI EK +I +T K + LN Sbjct: 826 DKEK-----IMKELESTIMEKNQIEEERKKEQEINEKKINDI-----ITSKDTKINELNK 875 Query: 337 QIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQ 396 I + +E K + ++ ++ + +I+ N K + +ET Sbjct: 876 SIIELKEEWNKKENNLNKSNQELTEQIIQKEEIINVTIKENENLKKVKEEIEKKTETEIN 935 Query: 397 DTDKKINKNEIAKLEMVIQSLNKDLVDKEYVIS-EKDTXXXXXXXXXXGKDTLIAQLQLE 455 + +KI +N E+ + K+ + KE+ I + K+ ++Q+E Sbjct: 936 ELQRKIKENNEQINEI---NKEKENIQKEFEIQIDNKNKEINEIKEKNEKEINEIKIQIE 992 Query: 456 HQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQL 515 + + E L ++ E+ NEI K + + K+E N E+ + +K+ +K++S +I Sbjct: 993 -EMNKEKNQLENLKKQLENENEIIKKENKKKEEENKEMGYL-IKENEKKIESIRNEINSK 1050 Query: 516 NDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFS-KVSDSNKEIVRLTEELHHLSQKVAEL 574 E+ K + +K+ + K +K +DN + ++ +I + ++ + QK E Sbjct: 1051 ERELGTKIKLIEMIKNEKDIMEKDFKKEVDNKNIEIKRLQIDIEKKKNDITLIIQKNDED 1110 Query: 575 E----EEKGNLQLHLVDYDSGRM-IESDVYKKMIEMENLAETRLKAISLLESQKFDLVQE 629 + EEK NL + S + ++ + + ++E E+L K + +E++K + +E Sbjct: 1111 KKKSIEEKKNLNQEIEKIKSEKNDVQKEKEQILLEKEDLQSDFNKYKTQMENEKLQIKEE 1170 Query: 630 -LHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLD 688 + + +E+ +K+ Q+D++ +I+ L +Q+D L E E Sbjct: 1171 HENNITNLQNEINEKIN-----QNDEIKLQIE--QLNKQLDELKQQLVETQKEKEEETKK 1223 Query: 689 KEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEE--QSK 746 E++ G I + E+I + + I + D+++K + E EL ++ + ++K Sbjct: 1224 YEEVKGQIDGAHQEVENIKKETEQQINQMKKECDEMQKTTFEAKEELRVQVESVKMIETK 1283 Query: 747 IQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQ 801 + TQ + K+++R +E +E + K K+ R E+ + + + +E + D+ Sbjct: 1284 VSTQKVSNTKLKKR---VEELERTIEKLKNE--RNEKEAFWEKKKMWMIEDEEDK 1333 Score = 67.3 bits (157), Expect = 3e-09 Identities = 127/667 (19%), Positives = 271/667 (40%), Gaps = 62/667 (9%) Query: 87 VPGISESLANTLKQKEILMEKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTH 146 V G+++ + K+ EI+ EK+K+ + + + +++ +L Sbjct: 693 VKGLNQEIDKINKENEIMKEKMKELERI--KGEIEVLKIKETGDSNEYEKMIEELKKQIE 750 Query: 147 LSNTIKEKDNALSVLQVKMKIMETTILDLQ------------EKINEKDQIIEAKNKATT 194 + EK+ + ++ K K E + + EK+N++ + ++ KN+ T Sbjct: 751 IIKNDNEKERKNNEIEQKKKNEEFNQKEEELNNDIEKKKKEIEKLNKQIEELKQKNEENT 810 Query: 195 XXXXXXXXXXXXXXXXXEDTKQQM--TKMQENFIAMEAEWKDE-KQRLLKD-IESKDVRI 250 E +++ T M++N I E + + E ++ + D I SKD +I Sbjct: 811 KENIEKQNQINQLNLDKEKIMKELESTIMEKNQIEEERKKEQEINEKKINDIITSKDTKI 870 Query: 251 SSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEI 310 + E NK + + E + + + L + ++ K++ E + K EI Sbjct: 871 N---ELNKSIIELKEEWNKKENNLNKSNQELTEQIIQKEEIINVTIKEN-ENLKKVKEEI 926 Query: 311 EEKGSLEIANM-TELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKK--GS 367 E+K EI + ++ + E + +N + KE E ++ E + ++K Sbjct: 927 EKKTETEINELQRKIKENNEQINEINKEKENIQKEFEIQIDNKNKEINEIKEKNEKEINE 986 Query: 368 PLISRKSGRNTASKMKSPWSQLSSET--LNQDTDKKINKNE-----IAKLEMVIQSLNKD 420 I + +++++ QL +E + ++ KK +N+ I + E I+S+ + Sbjct: 987 IKIQIEEMNKEKNQLENLKKQLENENEIIKKENKKKEEENKEMGYLIKENEKKIESIRNE 1046 Query: 421 LVDK-----------EYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVG 469 + K E + +EKD K+ I +LQ++ ++ +LI + Sbjct: 1047 INSKERELGTKIKLIEMIKNEKDIMEKDFKKEVDNKNIEIKRLQIDIEKKKNDITLI-IQ 1105 Query: 470 TNTEDVNEIAKVQEQLKQE---LNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNM 526 N ED + + ++ L QE + E DV K+ + L E+ + N Sbjct: 1106 KNDEDKKKSIEEKKNLNQEIEKIKSEKNDVQ-KEKEQILLEKEDLQSDFNKYKTQMENEK 1164 Query: 527 IKVKSNHKLKLKQMQKTIDNFSKVSDSNK-EIVRLTEELHHLSQKVAELEEEKGNLQLHL 585 +++K H+ + +Q I+ +D K +I +L ++L L Q++ E ++EK + Sbjct: 1165 LQIKEEHENNITNLQNEINEKINQNDEIKLQIEQLNKQLDELKQQLVETQKEKEE-ETKK 1223 Query: 586 VDYDSGRM--IESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDK 643 + G++ +V E E K ++ F+ +EL + + +E K Sbjct: 1224 YEEVKGQIDGAHQEVENIKKETEQQINQMKKECDEMQKTTFEAKEELRVQVESVKMIETK 1283 Query: 644 LADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDK 703 ++ ++ + ++ ++ LE I+ L + E E K+ I+D E DK Sbjct: 1284 VS-TQKVSNTKLKKRVE--ELERTIEKLKNERNEKEAFWEKKKM------WMIED-EEDK 1333 Query: 704 EDIMNKL 710 + + N L Sbjct: 1334 KVLFNSL 1340 >UniRef50_A2DGH5 Cluster: Viral A-type inclusion protein, putative; n=1; Trichomonas vaginalis G3|Rep: Viral A-type inclusion protein, putative - Trichomonas vaginalis G3 Length = 1579 Score = 149 bits (360), Expect = 8e-34 Identities = 255/1344 (18%), Positives = 555/1344 (41%), Gaps = 111/1344 (8%) Query: 296 AKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTE 355 A + I E ++EE+ +E+ ++ L K+ +++ LN Q+ + + ++ T+ Sbjct: 117 ATEDIAVLTAENKQLEEQ--VELYRLSSL-KQQSIIDELNSQL-SSPQVIDKPQRFADTK 172 Query: 356 SKAVSSPSKKG-SPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVI 414 + +KK S +IS + + ++ S + E Q TD N++E + I Sbjct: 173 IHLLQEKNKKLLSTVISLRKQQQISNVELSTQKSANRELTQQLTDALTNEDEDQDTIVHI 232 Query: 415 QSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTED 474 + ++ K+ V E + + + Q LE + + +NTE+ Sbjct: 233 EDMSSYPEVKKLV--EMNARKAKRIESLKSEINFMKQTILEQSEKEKTLIDFIESSNTEN 290 Query: 475 VNEIAKVQEQLKQELNDEIKDVNVK----DLIEKLKSAEEQITQLNDE--IDAANKNMIK 528 ++ ++ ++L N +I V +L + L + Q+T+L + I+ K+ +K Sbjct: 291 QKKLTEMNQRLSDFQNSKISQVTDDSQNTELRKSLDEMKSQLTELRKKSLIEEQQKSQLK 350 Query: 529 VK--------SNHKLKLKQMQKTI--DNFSKVSDSNKEIVRLTEELHHLSQKV----AEL 574 + S+ K KLK T N+S +E+ + T+E+ + + + L Sbjct: 351 TELEKVQSENSDLKEKLKFSSDTSFDSNYSMDPIFEQELQQKTKEISQMKVAINSLTSML 410 Query: 575 EEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQ 634 E + NLQ + + ++ I K+ + N +KAI + + F+ ++E +Q Sbjct: 411 SENEQNLQSQISEKENELQIAQQNIKRCQDELN----SMKAIQEEQGKSFNRIKEN--VQ 464 Query: 635 QKYDEVEDKLADISQLQSDQVCSEIKSV---------HLEEQIDALSASKKELALVIENL 685 D+V+ + S +D + S +K V ++ + L ++L ++ Sbjct: 465 VLLDDVQTSFSFASLKVTDDMDS-LKDVSKFICTNYNRSKDMVSQLQKENEDLKKELKQS 523 Query: 686 KLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQS 745 L ++L T+ DL + E KLQN + + + ++ K +K ++ IN E Sbjct: 524 NLKNKELSLTLNDLRSSTE---MKLQNTMSQQQ-MNEERMKEELQKSQNQISTIN--EMF 577 Query: 746 KIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSY 805 K Q + + L I+ E E K++I L + ++ + R+ + L + Sbjct: 578 K-QKSIEYEKDLATSHLTIDQFEEEKVNMKTKIDDLLDQLSAFQSRQTDFTSSINSLETT 636 Query: 806 LQEKQKAYSEYTIQEDELVNRLAVLMDH--DRV--VEKQLLEIEHENKELQKKNQILLEE 861 + K+K+ S+ Q ++ ++L + + +RV +E +L++ +ENK+++ K Q L+ E Sbjct: 637 YKNKEKSLSDTISQLNDDKSKLKLKEEQLTNRVNSMESAMLDLRNENKKIENKKQKLIVE 696 Query: 862 NQNLQISLSDM-QQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQ----- 915 N L+ +L + ++ L EK + + +++ + Q+++L+ +K + + Sbjct: 697 NNELKTALEEFTNENKTTLAEKDQKYYKLKETNSEMENQIKELKKEVKEQRKQFEDLKNQ 756 Query: 916 -TLIVQKKKE-IEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIEN 973 TL +Q K E I L ++ E+ + K ++K +N+E Q+ Q + E Sbjct: 757 STLSLQTKAEKINKLRLKLKQLQEAFVNLTKEKDQKERENVELQLQITGQSDTVRR-AEE 815 Query: 974 LNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKIN 1033 + + + + +K Q +Y + ++ + K +++ ++++ +K Sbjct: 816 QSQKMTAAKEAGDYVFKSLTKKYQDLQKEYAD-HLQFVEKSKEDIEEM-KKVVDDKEKER 873 Query: 1034 NAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIK 1093 + V M+ SKL + ++E+E ++S L + ++N LQI ++ ++IK Sbjct: 874 SDAVDQMNSTI---SKLENLQNEKNDIEKENSQLSSDLETANKNNTNLQIERKQNLEKIK 930 Query: 1094 EL--------KETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLK-- 1143 EL + + + N ++ ++ S E + +D + + K Sbjct: 931 ELTDNNQELKSQISVLQKQNHELSQNTVLLSVYEKLKNDKDELQKSFNFINDELHTTKSC 990 Query: 1144 -VQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHD--VVN--QEQINQ 1198 E++E+ + + ++ A L + +++ +I +++ N D +N Q+Q++ Sbjct: 991 YEMEDKEYTDYKDQMTKKVASLTSTIEDLNKEIAKIKDENDRAAQQDTQTINKLQDQVDS 1050 Query: 1199 LKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELR 1258 L+ KLE E + E+R +VD + L Q + K EL+ Sbjct: 1051 LRGKLETQTAEYSKIDEETKEIRKKSRESVDN-----IKAKNNELTQAIENKGKLIDELK 1105 Query: 1259 VQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVIN 1318 ++ E + ++ + + + KI +Q+ + Q+ Q+K + Y I Sbjct: 1106 NKIKELEDDKKDIMSNYDNLNAQ---KIEVEKQLNTTQSTQQEKFDDFTRKLSSYKQKI- 1161 Query: 1319 QIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTE--NQSYKQMQEQSILNINE---E 1373 E+E +K LR Y ++Q++ L E E Sbjct: 1162 ------KEMEADKATSERIIRENGLRIDELKSQLRNSVPKDDYNKLQKKIDLLKKEKLLE 1215 Query: 1374 NAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDE 1433 + L+K++ + E + QL+ + + + N E Sbjct: 1216 STVLQKTAFANEVNAEKLKDKFTRKEKDYQDQIEQLKQDRDKKAEAAKNLASQVKSLNQE 1275 Query: 1434 FENVRQQLVEYEKRIED--LTYEKESELAILRLKMHENANHYETMQ-KESEIERV-KLIE 1489 + V + E ++ E ++++ L L + N + +Q KE EIE + K IE Sbjct: 1276 LVKATENKVPMCPKAEKDAISMELKAKVEELALSETKLKNKDQIIQMKEKEIEELNKNIE 1335 Query: 1490 ELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEI----TNLQN 1545 +L +I E S + Q+ ELN+++ A + + I ++N+++ +L+ Sbjct: 1336 KLKDQIEEIKSNDDQIQELNESISNLAADNKSKDNEIASLTTTIRSMNEKLLSKTKDLEQ 1395 Query: 1546 MVRASSSKIQKHVSFASDTKQGRD 1569 M ++K K + + K +D Sbjct: 1396 MKSDMNNKNPKVIQLDNINKIAKD 1419 Score = 122 bits (294), Expect = 8e-26 Identities = 226/1201 (18%), Positives = 493/1201 (41%), Gaps = 107/1201 (8%) Query: 472 TEDVNEIAKVQEQLKQELN-DEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVK 530 TED+ + +QL++++ + + + +I++L S + Q+ D+ I + Sbjct: 118 TEDIAVLTAENKQLEEQVELYRLSSLKQQSIIDELNS-QLSSPQVIDKPQRFADTKIHLL 176 Query: 531 SNHKLKLKQMQKTIDNFSKVSD-SNKEIVRLTEELHHLSQKVAEL---EEEKGNLQLHLV 586 K K++ T+ + K SN E+ L+Q++ + E+E + +H+ Sbjct: 177 QE---KNKKLLSTVISLRKQQQISNVELSTQKSANRELTQQLTDALTNEDEDQDTIVHIE 233 Query: 587 DYDS----GRMIESDVYK-KMIEMENLAETRLKAISLLESQK----FDLVQELHIL-QQK 636 D S +++E + K K IE +K L +S+K D ++ + Q+K Sbjct: 234 DMSSYPEVKKLVEMNARKAKRIESLKSEINFMKQTILEQSEKEKTLIDFIESSNTENQKK 293 Query: 637 YDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTI 696 E+ +L+D + QV + ++ L + +D + + EL + K QL + Sbjct: 294 LTEMNQRLSDFQNSKISQVTDDSQNTELRKSLDEMKSQLTELRKKSLIEEQQKSQLKTEL 353 Query: 697 KDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAK 756 + ++++ D+ KL+ + D ++ + +++ + +I+ + + + Sbjct: 354 EKVQSENSDLKEKLKFSSDTSFDSNYSMDPIFEQELQQKTKEISQMKVAINSLTSMLSEN 413 Query: 757 IQERDLYIENIESELSKYKSRICRLEESI----AVMEDRRYSLERKADQLGSYLQEKQKA 812 Q I E+EL + I R ++ + A+ E++ S R + + L + Q + Sbjct: 414 EQNLQSQISEKENELQIAQQNIKRCQDELNSMKAIQEEQGKSFNRIKENVQVLLDDVQTS 473 Query: 813 YS----EYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQIS 868 +S + T D L + + + + + +++ EN++L+K+ + +N+ L ++ Sbjct: 474 FSFASLKVTDDMDSLKDVSKFICTNYNRSKDMVSQLQKENEDLKKELKQSNLKNKELSLT 533 Query: 869 LSDMQQH-----YNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKK 923 L+D++ N + ++ + + E K Q Q+ + K+ + E++ + Sbjct: 534 LNDLRSSTEMKLQNTMSQQQMNEERMKEELQKSQNQISTINEMFKQKSIEYEKDLATSHL 593 Query: 924 EIEDLEIEFNTQIESAIRD-KKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELN 982 I+ E E +++ I D L+ + ++ + + + YKN ++L+ + +LN Sbjct: 594 TIDQFE-EEKVNMKTKIDDLLDQLSAFQSRQTDFTSSINSLETTYKNKEKSLSDTISQLN 652 Query: 983 KMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSM 1042 +L K ++Q T + E + ++ N ++ K +++I N ++ A + + Sbjct: 653 DDKSKL--KLKEEQLTNRVNSMESAMLDLRNENKKIENKKQKLIVENNELKTALEEFTNE 710 Query: 1043 VSDYESKLAQFTTKLENMEEEMQRVSKQL-LDSKQHNEELQILVREQDDQIKELKETKLT 1101 ++ Q KL+ EM+ K+L + K+ ++ + L + ++ E Sbjct: 711 NKTTLAEKDQKYYKLKETNSEMENQIKELKKEVKEQRKQFEDLKNQSTLSLQTKAEKINK 770 Query: 1102 FEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFI----QERSVL 1157 + + + + ++ T E + NV+ + +E+ + + + + Sbjct: 771 LRLKLKQLQEAFVNLTKEKDQKERENVELQLQITGQSDTVRRAEEQSQKMTAAKEAGDYV 830 Query: 1158 QEQSAKLNTELQECYTKIIQ--------LETLNTELTGHDVVNQEQINQLK---SKLEQL 1206 + K +LQ+ Y +Q +E + + + + ++Q+ SKLE L Sbjct: 831 FKSLTKKYQDLQKEYADHLQFVEKSKEDIEEMKKVVDDKEKERSDAVDQMNSTISKLENL 890 Query: 1207 NTENDNLLSTVAELRSSISSA----------VDQRGFEIAELW--KQHLAQREADFQKTE 1254 E +++ ++L S + +A Q +I EL Q L + + QK Sbjct: 891 QNEKNDIEKENSQLSSDLETANKNNTNLQIERKQNLEKIKELTDNNQELKSQISVLQKQN 950 Query: 1255 HELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKE--EHLRNLQEK 1312 HEL Q + S YE+L + + Q+ N I T +++DKE ++ + +K Sbjct: 951 HELS-QNTVLLSVYEKLKND-KDELQKSFNFINDELHTTKSCYEMEDKEYTDYKDQMTKK 1008 Query: 1313 YADVINQIEILRSE---IEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILN 1369 A + + IE L E I+DE LR + ++ Q E S Sbjct: 1009 VASLTSTIEDLNKEIAKIKDENDRAAQQDTQTINKLQDQVDSLRGKLET--QTAEYS--K 1064 Query: 1370 INEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKD---SEIYQKTHEYTIT 1426 I+EE +++K S V++ +AK ELT +E K E+ K E Sbjct: 1065 IDEETKEIRKKSRES----------VDNIKAKNNELTQAIENKGKLIDELKNKIKELEDD 1114 Query: 1427 LTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKE-SEIERV 1485 ++N+ Q +E EK++ ++ + K+ + M+ + + ER+ Sbjct: 1115 KKDIMSNYDNLNAQKIEVEKQLNTTQSTQQEKFDDFTRKLSSYKQKIKEMEADKATSERI 1174 Query: 1486 -----KLIEELNVKITESV---SLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLN 1537 I+EL ++ SV NK +++ +E++ ++ +Q E+ L Sbjct: 1175 IRENGLRIDELKSQLRNSVPKDDYNKLQKKIDLLKKEKLLESTVLQKTAFANEVNAEKLK 1234 Query: 1538 DEIT--------NLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAEL 1589 D+ T ++ + + K + + AS K E + T NK + P+AE Sbjct: 1235 DKFTRKEKDYQDQIEQLKQDRDKKAEAAKNLASQVKSLNQELVKATENK--VPMCPKAEK 1292 Query: 1590 D 1590 D Sbjct: 1293 D 1293 Score = 121 bits (291), Expect = 2e-25 Identities = 186/912 (20%), Positives = 383/912 (41%), Gaps = 79/912 (8%) Query: 148 SNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXX 207 S+T + N +S Q+ + M+ + Q +I+ +++ + K+ Sbjct: 539 SSTEMKLQNTMSQQQMNEERMKEELQKSQNQISTINEMFKQKS----IEYEKDLATSHLT 594 Query: 208 XXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEI 267 E+ K M ++ + + ++ + I S + + E K L ++ Sbjct: 595 IDQFEEEKVNMKTKIDDLLDQLSAFQSRQTDFTSSINSLETTYKNKE---KSLSDTISQL 651 Query: 268 SLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTK- 326 + + SKL + EQ L ++ + +++ I E L+ A + E T Sbjct: 652 NDDKSKLKLKEEQLTNRVNSMESAMLDLRNENKKIENKKQKLIVENNELKTA-LEEFTNE 710 Query: 327 -KIELLE--HLNCQIRQTNKELENKLATMGTESKAVSSPSK--KGSPLISRKSGRNTASK 381 K L E ++++TN E+EN++ + E K + K +S ++ +K Sbjct: 711 NKTTLAEKDQKYYKLKETNSEMENQIKELKKEVKEQRKQFEDLKNQSTLSLQTKAEKINK 770 Query: 382 MKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXX 441 ++ QL +N +K + E +L++ I D V + S+K T Sbjct: 771 LRLKLKQLQEAFVNLTKEKDQKERENVELQLQITG-QSDTVRRAEEQSQKMTAAKEAGDY 829 Query: 442 XXGKDTLIAQ-LQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVN--- 497 T Q LQ E+ H++ V + ED+ E+ KV + ++E +D + +N Sbjct: 830 VFKSLTKKYQDLQKEYADHLQ-----FVEKSKEDIEEMKKVVDDKEKERSDAVDQMNSTI 884 Query: 498 --VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNK 555 +++L + E++ +QL+ +++ ANKN ++ K L+++++ DN ++ Sbjct: 885 SKLENLQNEKNDIEKENSQLSSDLETANKNNTNLQIERKQNLEKIKELTDNNQELKS--- 941 Query: 556 EIVRLTEELHHLSQKVA------ELEEEKGNLQ---------LHLVD--YDSGRMIESD- 597 +I L ++ H LSQ +L+ +K LQ LH Y+ +D Sbjct: 942 QISVLQKQNHELSQNTVLLSVYEKLKNDKDELQKSFNFINDELHTTKSCYEMEDKEYTDY 1001 Query: 598 ---VYKKMIEMENLAETRLKAISLLESQKFDLVQE----LHILQQKYDEVEDKLADISQL 650 + KK+ + + E K I+ ++ + Q+ ++ LQ + D + KL + Sbjct: 1002 KDQMTKKVASLTSTIEDLNKEIAKIKDENDRAAQQDTQTINKLQDQVDSLRGKL-ETQTA 1060 Query: 651 QSDQVCSEIKSVHLE--EQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMN 708 + ++ E K + + E +D + A EL IEN ++L IK+LE+DK+DIM+ Sbjct: 1061 EYSKIDEETKEIRKKSRESVDNIKAKNNELTQAIENKGKLIDELKNKIKELEDDKKDIMS 1120 Query: 709 KLQNYIQENMDLTDKL---EKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIE 765 N + +++ +L + EK + K++ +Q KI+ + D ER I Sbjct: 1121 NYDNLNAQKIEVEKQLNTTQSTQQEKFDDFTRKLSSYKQ-KIK-EMEADKATSER--IIR 1176 Query: 766 NIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVN 825 + + KS++ +V +D L++K D L +K+K +Q+ N Sbjct: 1177 ENGLRIDELKSQLRN-----SVPKDDYNKLQKKID-----LLKKEKLLESTVLQKTAFAN 1226 Query: 826 RLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQH-YNALVEKAN 884 + D+ K+ + + + ++L++ E +NL + + Q A K Sbjct: 1227 EVNAEKLKDKFTRKE-KDYQDQIEQLKQDRDKKAEAAKNLASQVKSLNQELVKATENKVP 1285 Query: 885 RTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQ-KKKEIEDLEIEFNTQIESAIRDK 943 AE ++ + + + E L +++ I+Q K+KEIE+L +++ I + Sbjct: 1286 MCPKAEKDAISMELKAKVEELALSETKLKNKDQIIQMKEKEIEELNKNIE-KLKDQIEEI 1344 Query: 944 KVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELN-KMNLELIDKHVQKQQTQSPD 1002 K +++ ++ E ++ L A + N I +L + +N K+ + D K + + Sbjct: 1345 KSNDDQIQELNESISNLAADNKSKDNEIASLTTTIRSMNEKLLSKTKDLEQMKSDMNNKN 1404 Query: 1003 YTEQYINEINKL 1014 ++ INK+ Sbjct: 1405 PKVIQLDNINKI 1416 Score = 90.6 bits (215), Expect = 3e-16 Identities = 168/916 (18%), Positives = 370/916 (40%), Gaps = 64/916 (6%) Query: 665 EEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQEN-MDLTDK 723 E +I K+ +L EN KL K +L + ++ +KE+ N+ QN ++ N +D+ +K Sbjct: 56 EMRITQAKMIKQIESLNKENRKL-KLELDCSQNQIQENKEEHNNE-QNTLKNNILDMKNK 113 Query: 724 LEKMSAEKISELLAKINH-EEQSKIQTQFGIDAK--IQERDLYIEN---IESELSKYKSR 777 L + + E I+ L A+ EEQ ++ + + I E + + + I+ ++ Sbjct: 114 LRR-ATEDIAVLTAENKQLEEQVELYRLSSLKQQSIIDELNSQLSSPQVIDKPQRFADTK 172 Query: 778 ICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQE--DELVNRLAVLMDHDR 835 I L+E + SL RK Q+ + QK+ + Q+ D L N D D Sbjct: 173 IHLLQEKNKKLLSTVISL-RKQQQISNVELSTQKSANRELTQQLTDALTNEDE---DQDT 228 Query: 836 VVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRT-DLAESEST 894 +V + + E K+L + N + ++L+ ++ M+Q EK D ES +T Sbjct: 229 IVHIEDMSSYPEVKKLVEMNARKAKRIESLKSEINFMKQTILEQSEKEKTLIDFIESSNT 288 Query: 895 KYQTQLRDLESNLKRITHEHQTLIVQKKK--EIEDLEIEFNTQIESAIRDKKVLNEKYEK 952 + Q +L ++ L + + + + E+ E +Q+ + +R K ++ E+ + Sbjct: 289 ENQKKLTEMNQRLSDFQNSKISQVTDDSQNTELRKSLDEMKSQL-TELRKKSLIEEQQKS 347 Query: 953 NIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEIN 1012 ++ T+LE E + E L + + N + Q+ Q ++ + ++ + IN Sbjct: 348 QLK--TELEKVQSENSDLKEKLKFSSDTSFDSNYSMDPIFEQELQQKTKEISQMKV-AIN 404 Query: 1013 KLNALLKQKDEEIIA-LNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQ- 1070 L ++L + ++ + + +++K N Q++ + + + +L E + R+ + Sbjct: 405 SLTSMLSENEQNLQSQISEKENELQIAQQN-IKRCQDELNSMKAIQEEQGKSFNRIKENV 463 Query: 1071 --LLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMI--ISSTIEPMSDDAN 1126 LLD Q + L + D + LK+ N +++ M+ + E + + Sbjct: 464 QVLLDDVQTSFSFASL--KVTDDMDSLKDVSKFICTNYNRSKDMVSQLQKENEDLKKELK 521 Query: 1127 NVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELT 1186 + L+ E + S Q ++ ELQ+ Q+ T+N Sbjct: 522 QSNLKNKELSLTLNDLRSSTEMKLQNTMSQQQMNEERMKEELQKSQN---QISTINEMFK 578 Query: 1187 GHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQR 1246 + ++ + ++Q E N+ + + +L +S+ R Sbjct: 579 QKSIEYEKDLATSHLTIDQFEEEKVNMKTKIDDLLDQLSA----------------FQSR 622 Query: 1247 EADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHL 1306 + DF + + L + +++K + L D++ +++ + EQ+T+ N ++ L Sbjct: 623 QTDFTSSINSLE---TTYKNKEKSLSDTISQLNDDKSKLKLKEEQLTNRVNSMESAMLDL 679 Query: 1307 RNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQS 1366 RN +K + ++ + +E++ F L+ N + ++ Sbjct: 680 RNENKKIENKKQKLIVENNELKTALEEFTNENKTTLAEKDQKYYKLKETNSEMENQIKEL 739 Query: 1367 ILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTH---EY 1423 + E+ Q + ++N K+ +L E QK E Sbjct: 740 KKEVKEQRKQFEDLKNQSTLSLQTKAEKINKLRLKLKQLQEAFVNLTKEKDQKERENVEL 799 Query: 1424 TITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESE-I 1482 + +T ++D +Q + E Y +S + E A+H + ++K E I Sbjct: 800 QLQITGQSDTVRRAEEQSQKMTAAKEAGDYVFKSLTKKYQDLQKEYADHLQFVEKSKEDI 859 Query: 1483 ERV-KLIEELNVKITESV-SLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEI 1540 E + K++++ + +++V +N +++L E+ N+++ ++ T N Sbjct: 860 EEMKKVVDDKEKERSDAVDQMNSTISKLENLQNEK----NDIEKENSQLSSDLETANKNN 915 Query: 1541 TNLQNMVRASSSKIQK 1556 TNLQ + + KI++ Sbjct: 916 TNLQIERKQNLEKIKE 931 Score = 76.2 bits (179), Expect = 7e-12 Identities = 141/720 (19%), Positives = 296/720 (41%), Gaps = 73/720 (10%) Query: 923 KEIEDLEIEFNT-QIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEEL 981 K+IE L E ++E ++ K E N E T L+ + + KN + ++ L Sbjct: 66 KQIESLNKENRKLKLELDCSQNQIQENKEEHNNEQNT-LKNNILDMKNKLRRATEDIAVL 124 Query: 982 NKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMS 1041 N +L ++ V+ + S + I+E+N + + D+ + KI+ Q Sbjct: 125 TAENKQL-EEQVELYRLSSLKQ-QSIIDELNSQLSSPQVIDKPQRFADTKIHLLQEKNKK 182 Query: 1042 MVSDYES--KLAQFTT-KLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKET 1098 ++S S K Q + +L + + +++QL D+ + +E Q + +D + E Sbjct: 183 LLSTVISLRKQQQISNVELSTQKSANRELTQQLTDALTNEDEDQDTIVHIED-MSSYPEV 241 Query: 1099 KLTFEMNIPKTEGM--------IISSTIEPMSDDANN-VDXXXXXXXXXXXXL-KVQEEE 1148 K EMN K + + + TI S+ +D L ++ + Sbjct: 242 KKLVEMNARKAKRIESLKSEINFMKQTILEQSEKEKTLIDFIESSNTENQKKLTEMNQRL 301 Query: 1149 EFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNT 1208 Q + Q NTEL++ + ++++ TEL ++ ++Q +QLK++LE++ + Sbjct: 302 SDFQNSKISQVTDDSQNTELRK---SLDEMKSQLTELRKKSLIEEQQKSQLKTELEKVQS 358 Query: 1209 ENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKY 1268 EN +L +L+ S ++ D + + +++Q L Q+ + +++V +++ S Sbjct: 359 ENSDLKE---KLKFSSDTSFDSN-YSMDPIFEQELQQKTKEIS----QMKVAINSLTSML 410 Query: 1269 EQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQI-EILRSEI 1327 + ++QS E+ N++ +Q + QD+ ++ +QE+ N+I E ++ + Sbjct: 411 SENEQNLQSQISEKENELQIAQQNIK---RCQDELNSMKAIQEEQGKSFNRIKENVQVLL 467 Query: 1328 EDEKVAFXXXXXXXXXXXXXXX-----------------XDLRTENQSYKQMQEQSILNI 1370 +D + +F L+ EN+ K+ +QS L Sbjct: 468 DDVQTSFSFASLKVTDDMDSLKDVSKFICTNYNRSKDMVSQLQKENEDLKKELKQSNLKN 527 Query: 1371 NEENAQLK--KSSXXXXXXXXXXXXRVNDAEAK--VLELTHQLELKDSEIYQKTHEYTIT 1426 E + L +SS ++N+ K + + +Q+ + QK+ EY Sbjct: 528 KELSLTLNDLRSSTEMKLQNTMSQQQMNEERMKEELQKSQNQISTINEMFKQKSIEYEKD 587 Query: 1427 LTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVK 1486 L + + ++ V + +I+DL ++ S + + N ET K E Sbjct: 588 LATSHLTIDQFEEEKVNMKTKIDDLL-DQLSAFQSRQTDFTSSINSLETTYKNKEKSLSD 646 Query: 1487 LIEELN-----VKITESVSLNK---------QVAELNKALEEE----VAKTNEMQTALEN 1528 I +LN +K+ E N+ + NK +E + + + NE++TALE Sbjct: 647 TISQLNDDKSKLKLKEEQLTNRVNSMESAMLDLRNENKKIENKKQKLIVENNELKTALEE 706 Query: 1529 QEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAE 1588 E T E ++ ++S+++ + + + +Q ++ N+ L +AE Sbjct: 707 FTNENKTTLAEKDQKYYKLKETNSEMENQIKELKKEVKEQRKQFEDLKNQSTLSLQTKAE 766 Score = 38.3 bits (85), Expect = 1.7 Identities = 50/289 (17%), Positives = 113/289 (39%), Gaps = 11/289 (3%) Query: 220 KMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELE 279 K+++ F E +++D+ ++L +D + K +L K L + + + + E Sbjct: 1232 KLKDKFTRKEKDYQDQIEQLKQDRDKKAEAAKNLASQVKSLNQELVKATENKVPMCPKAE 1291 Query: 280 QXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEI-ANMTELTKKIELLEHLNCQI 338 + ++ + ++ +++EK E+ N+ +L +IE ++ + QI Sbjct: 1292 KDAISMELKAKVEELALSETKLKNKDQIIQMKEKEIEELNKNIEKLKDQIEEIKSNDDQI 1351 Query: 339 RQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDT 398 ++ N+ + N A ++ ++S + R SK K Q+ S+ +N Sbjct: 1352 QELNESISNLAADNKSKDNEIASLTTT-----IRSMNEKLLSKTKD-LEQMKSD-MNNKN 1404 Query: 399 DKKINKNEIAKLEM-VIQSLNKDLVDKEYVISEKDTXXXXXXXXXX--GKDTLIAQLQLE 455 K I + I K+ ++ +N K+ + T G + Sbjct: 1405 PKVIQLDNINKIAKDLLNIINSPQFAKQQALQRLSTLQDSISTIFTILGLPSSNIMPPAR 1464 Query: 456 HQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEK 504 H +GP G + + E K+ E + +E + K+V D +++ Sbjct: 1465 ALSHQQGPIFYIPGDKSLETKEERKIAELIIREFPELGKEVTDSDSLDR 1513 >UniRef50_UPI0000D565C6 Cluster: PREDICTED: similar to CG3493-PA; n=1; Tribolium castaneum|Rep: PREDICTED: similar to CG3493-PA - Tribolium castaneum Length = 1398 Score = 148 bits (359), Expect = 1e-33 Identities = 248/1219 (20%), Positives = 527/1219 (43%), Gaps = 105/1219 (8%) Query: 147 LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINE--KDQIIEAKNKATTXXXXXXXXXX 204 L + I EK + LQ K+++++T + + +N+ D +E +N Sbjct: 189 LRDEIDEKQFKIESLQTKIELLQTPETENPDTLNKYLTDARVEIEN--LNQRIQEMKANS 246 Query: 205 XXXXXXXEDTKQQMTKMQENFIAMEAEWKDE--------KQRLLKDIESKDVRISSLEEA 256 ++ K ++T +++ IA+ +E + E K L ++ SKD IS+L+++ Sbjct: 247 IIFQTKEQEYKAKITNLEKE-IALFSEREKENNLSLAQNKMELHNELLSKDAEISNLKKS 305 Query: 257 NKLLEAA--RFE-ISLEHSKLAQELEQXXXXXXXXXXXXXXLA--KQSIEPSCEEKTEIE 311 + L +FE + +++KL ++LE + ++ E + K EI+ Sbjct: 306 LEALTGGTGKFENLQTQNTKLIEKLEALTQKCNNYENKLLKMEQLRRENEENSRLKKEIQ 365 Query: 312 E-KGSLEIANMTELTKKIELLEHLNCQIRQT-NKELENKLATMGTE-SKAVSSPSKKGSP 368 + +G LE + E KK LL L +IR+ KE E K + ++ K + S S Sbjct: 366 DIQGQLE--GVREEAKK-SLLS-LETKIREKLAKEFEEKEERLRSDFRKKIEEVSSSSSN 421 Query: 369 LISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAK--LEMVIQS--LNKDL--V 422 + K++ Q++ L Q T K +++ + LE++ +S L + + Sbjct: 422 EFNLLEMEEEIRKLR----QVNDGILEQLTSKTTKYDDLERNHLELIEESGRLRSQIGGL 477 Query: 423 DKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGP--SLIHVGTN-TEDVNEIA 479 +KE + + + + +E + +E L+ N ED+ E Sbjct: 478 EKELATLQNTNQAANLKLGHLEANARVLERTVEEYKRLEAERDDLLQEKKNFMEDLEEER 537 Query: 480 KVQEQLKQELNDEIKDVNVK--DLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKL 537 ++ E+L E+ ++++D VK DL L+ + +LN E++ VK + + K Sbjct: 538 RINERLNLEV-EQLRDEMVKKSDLEHSLEEERKVTQKLNTELE-------NVKCHIEEKK 589 Query: 538 KQMQKTIDNFSKVSDSNKEIVRLTEE---LHHLSQKVAELEEEKGNLQLHLVDYDSGRMI 594 K ++ T+D + K + +L E + HL L EE +L+L + Sbjct: 590 KDLELTLDE-----EKGKLLQKLEESSVNMKHLEDTGLALSEELNSLKLKNEELAKLAEE 644 Query: 595 ESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQ-LQSD 653 + KK+ E E + + I LE + L ++K E+ ++ + L+ + Sbjct: 645 RDTLLKKLTESEETNSLQTRKIQNLEEEMAKKAVSLEEAKRKILELGEQNNSLGHNLEEE 704 Query: 654 QVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNY 713 + ++ LE + KK L L LD+E+ K L+N +E +K + Sbjct: 705 RNVNQKLHSDLEHMKRHIEEKKKHL-----ELSLDEERA----KLLQNLEES--SKTMKH 753 Query: 714 IQE-NMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELS 772 ++E ++ LT++L ++ +E LAK+ E + ++ + + L I+N+E E+ Sbjct: 754 LEETSLALTEELNELKIR--NEELAKVAEERDTLLKKLTESEENNSLQALQIQNLEEEMV 811 Query: 773 KYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMD 832 K + + I +E++ SL+ ++ + Q+ +E L +D Sbjct: 812 KTVQTLEETKRKIQELEEKNNSLQHSLEEERNVNQKLTTELEHVKRHIEEKKKDLESTLD 871 Query: 833 HDRVVEKQLLEIEHEN-KELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAES 891 +R Q LE + K L++ L EE L+I+ + + + + LV+K ++ S Sbjct: 872 EERAKLLQKLEESSKTMKHLEETGFALTEELNELKINNAKVAEERDTLVKKLTDSEETNS 931 Query: 892 ESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDK-----KVL 946 T L + NL + ++ +E+E+ E +++ + DK + L Sbjct: 932 LQTLKIQNLEEEMRNLFASLENERKNSIKAGEELEEKEANLK-KLKMLLEDKENDFVRQL 990 Query: 947 NEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQ 1006 +EK E ++ + ++E ++ K ++ N N+ N +E+ + ++ + Q E Sbjct: 991 DEK-ESRLKKIEEMEEEISSLKKLLDEANNNLAVKNHQ-IEIYEADLKTKNGQ----IEA 1044 Query: 1007 YINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESK-LAQFTTKLENMEE--- 1062 +I + N L+++++E + ++N ++ + ++K L KL+N E+ Sbjct: 1045 LSRKIEEYNDLIEERNEGFFKI---LSNFSEPLNNVRRNKDNKHLYNLEQKLQNFEQTFS 1101 Query: 1063 -EMQRVSKQLLDSKQHNEELQILVREQDDQIKELKET-KLTFEMNIPKTEGMIISSTIEP 1120 E + ++K L+ KQ E+ L E+++ ++++ E K E+N ++ I Sbjct: 1102 LERENLAKILIYLKQFEEKHSALEEEKEELLRQITELRKQIVEVNSAQSYVKQFEEEILR 1161 Query: 1121 MSDDANNVDXXXXXXXXXXXXLKVQEEE-EFIQERSVLQEQSAKLNTELQECYTKIIQLE 1179 + ++ NV L+++ + + + + L E++ L TE++E K + E Sbjct: 1162 LREE--NVRLMEEQEKFKQNVLELESRNTQVVSDSNFLSEENHGLLTEIEELKLKNEEYE 1219 Query: 1180 TLNTELTGH-----DVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFE 1234 T + L NQ Q+ +L+ L +L E LL + EL+++ +A ++ Sbjct: 1220 TKHKNLLSQIENLERESNQSQLAELEKHLTELQHEKQLLLEEIDELKTTPINAANKSEDY 1279 Query: 1235 IAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTS 1294 + E+ ++L + ++ + R + +E++ ++L + + ++ +VT+ + Sbjct: 1280 VKEI--ENLRTKIVQYKSLDLTNRSSIEFYENELQKLKNQNEKLNRKLDETLVTLNHCSE 1337 Query: 1295 LQNKLQDKEEHLRNLQEKY 1313 L N + E+L+N+ Y Sbjct: 1338 LSNSTE--IEYLKNVLYNY 1354 Score = 130 bits (315), Expect = 2e-28 Identities = 288/1383 (20%), Positives = 579/1383 (41%), Gaps = 108/1383 (7%) Query: 213 DTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHS 272 D Q + ENF ++ AE L+ E+K R S+ A+ + R+E Sbjct: 29 DRLQNSSTSDENFFSI-AEDGFTNVSLVSPQENKMRRNSNSSIASDVSFLPRYESFANMY 87 Query: 273 KLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLE 332 L +L+ L S E + + + T+L K + LE Sbjct: 88 HLQSDLDISASEIEDNASNSSQLGHLSKEQIYSAFQKAQMRYHKYRGRYTDLAKHYKDLE 147 Query: 333 HLNCQIRQTNKELENKLATMGTESK---AVSSPSKKGSPLISRKSGRNTASKMKSPWSQL 389 N +++ E ++K TE K A+ +K R K++S +++ Sbjct: 148 RENAKMKSVLVETQDKAIRRVTELKEQCALEQKAKAHLESALRDEIDEKQFKIESLQTKI 207 Query: 390 ----SSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGK 445 + ET N DT K + ++E + Q + +++ + K+ + Sbjct: 208 ELLQTPETENPDTLNKYLTDARVEIENLNQRI-QEMKANSIIFQTKEQEYKAKITNLEKE 266 Query: 446 DTLIAQLQLEHQQHMEGPSL-IHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKD---- 500 L ++ + E+ + + +H ++D EI+ +++ L+ K N++ Sbjct: 267 IALFSEREKENNLSLAQNKMELHNELLSKDA-EISNLKKSLEALTGGTGKFENLQTQNTK 325 Query: 501 LIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRL 560 LIEKL++ ++ +++ + + + N +LK K++Q V + K+ + Sbjct: 326 LIEKLEALTQKCNNYENKLLKMEQLRRENEENSRLK-KEIQDIQGQLEGVREEAKKSLLS 384 Query: 561 TEELHHLSQKVA-ELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLL 619 E + +K+A E EE++ L+ D + IE +V NL E + I L Sbjct: 385 LET--KIREKLAKEFEEKEERLRS-----DFRKKIE-EVSSSSSNEFNLLEME-EEIRKL 435 Query: 620 ESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELA 679 ++++L KYD++E ++ + +S ++ S+I LE+++ L + + Sbjct: 436 RQVNDGILEQLTSKTTKYDDLERNHLELIE-ESGRLRSQIGG--LEKELATLQNTNQAAN 492 Query: 680 LVIENLKLDKEQLYGTIKD---LENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELL 736 L + +L+ + L T+++ LE +++D++ + +N+++ DL + E+ E+++ + Sbjct: 493 LKLGHLEANARVLERTVEEYKRLEAERDDLLQEKKNFME---DLEE--ERRINERLNLEV 547 Query: 737 AKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAV-MEDRRYSL 795 ++ E K + ++ +ER + + + +EL K I ++ + + +++ + L Sbjct: 548 EQLRDEMVKKSDLEHSLE---EERKV-TQKLNTELENVKCHIEEKKKDLELTLDEEKGKL 603 Query: 796 ERKADQLG---SYLQEKQKAYSEYTIQEDELVNR-LAVLMDHDRVVEKQLLEIEHENKEL 851 +K ++ +L++ A SE + +L N LA L + + K+L E E N Sbjct: 604 LQKLEESSVNMKHLEDTGLALSE-ELNSLKLKNEELAKLAEERDTLLKKLTESEETNSLQ 662 Query: 852 QKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRIT 911 +K Q L EE +SL + ++ L E+ N E +L ++KR Sbjct: 663 TRKIQNLEEEMAKKAVSLEEAKRKILELGEQNNSLGHNLEEERNVNQKLHSDLEHMKR-- 720 Query: 912 HEHQTLIVQKKKEIE-DLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNN 970 H I +KKK +E L+ E +++ K + E ++ L +L E K Sbjct: 721 --H---IEEKKKHLELSLDEERAKLLQNLEESSKTMKHLEETSLA----LTEELNELKIR 771 Query: 971 IENLNMNVEELNKMNLELIDKHVQK--QQTQSPDYTEQYINEINKLNALLKQKDEEIIAL 1028 E L EE + + +L + Q Q + E+ + + L K+K +E L Sbjct: 772 NEELAKVAEERDTLLKKLTESEENNSLQALQIQNLEEEMVKTVQTLEET-KRKIQE---L 827 Query: 1029 NQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQIL--VR 1086 +K N+ Q S + + + + TT+LE+++ ++ K L +S E ++L + Sbjct: 828 EEKNNSLQHS----LEEERNVNQKLTTELEHVKRHIEEKKKDL-ESTLDEERAKLLQKLE 882 Query: 1087 EQDDQIKELKET--KLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKV 1144 E +K L+ET LT E+N K ++ + + + + L+ Sbjct: 883 ESSKTMKHLEETGFALTEELNELKINNAKVAEERDTLVKKLTDSEETNSLQTLKIQNLEE 942 Query: 1145 QEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLE 1204 + F + ++ S K EL+E + +L+ L E +D V Q +++ +S+L+ Sbjct: 943 EMRNLFASLENE-RKNSIKAGEELEEKEANLKKLKML-LEDKENDFVRQ--LDEKESRLK 998 Query: 1205 QLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAF 1264 ++ E + +S++ +L ++ + + +I E+++ L + + ++ Sbjct: 999 KIE-EMEEEISSLKKLLDEANNNLAVKNHQI-EIYEADLKTKNGQIEALSRKIEEYNDLI 1056 Query: 1265 ESKYEQLLDSVQSSTQEETNKI---VTMEQVTSLQNKLQDKEEHLRNLQEKYADVI---N 1318 E + E + S+ E N + + + +L+ KLQ+ E+ +E A ++ Sbjct: 1057 EERNEGFF-KILSNFSEPLNNVRRNKDNKHLYNLEQKLQNFEQTFSLERENLAKILIYLK 1115 Query: 1319 QIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLK 1378 Q E S +E+EK QSY + E+ IL + EEN +L Sbjct: 1116 QFEEKHSALEEEKEELLRQITELRKQIVEV-----NSAQSYVKQFEEEILRLREENVRLM 1170 Query: 1379 KSSXXXXXXXXXXXXR----VNDAEAKVLELTHQLELKDSEIYQKTHEYTI----TLTQ- 1429 + R V+D+ + E H L + E+ K EY L+Q Sbjct: 1171 EEQEKFKQNVLELESRNTQVVSDSNF-LSEENHGLLTEIEELKLKNEEYETKHKNLLSQI 1229 Query: 1430 RNDEFENVRQQLVEYEKRIEDLTYEKE---SELAILRLKMHENANHYETMQKESEIERVK 1486 N E E+ + QL E EK + +L +EK+ E+ L+ AN E KE E R K Sbjct: 1230 ENLERESNQSQLAELEKHLTELQHEKQLLLEEIDELKTTPINAANKSEDYVKEIENLRTK 1289 Query: 1487 LIEELNVKITESVSLNKQVAELNKALEEEVAKTNEM--QTALENQEIEIVTLNDEITNLQ 1544 +++ ++ +T S+ EL K L+ + K N +T + ++ + EI L+ Sbjct: 1290 IVQYKSLDLTNRSSIEFYENELQK-LKNQNEKLNRKLDETLVTLNHCSELSNSTEIEYLK 1348 Query: 1545 NMV 1547 N++ Sbjct: 1349 NVL 1351 Score = 125 bits (302), Expect = 9e-27 Identities = 171/870 (19%), Positives = 376/870 (43%), Gaps = 55/870 (6%) Query: 143 DVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXX 202 ++ L NT + + L L+ +++E T+ + + E+D +++ K K Sbjct: 480 ELATLQNTNQAANLKLGHLEANARVLERTVEEYKRLEAERDDLLQEK-KNFMEDLEEERR 538 Query: 203 XXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEA 262 E + +M K + ++E E K Q+L ++E+ I EE K LE Sbjct: 539 INERLNLEVEQLRDEMVKKSDLEHSLEEERK-VTQKLNTELENVKCHI---EEKKKDLEL 594 Query: 263 ARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQ--SIEPSCEEKTEIEEKGSLEIAN 320 E E KL Q+LE+ L+++ S++ EE ++ E+ + Sbjct: 595 TLDE---EKGKLLQKLEESSVNMKHLEDTGLALSEELNSLKLKNEELAKLAEERDTLLKK 651 Query: 321 MTE-------LTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRK 373 +TE T+KI+ LE + + +E + K+ +G ++ ++ + + +++K Sbjct: 652 LTESEETNSLQTRKIQNLEEEMAKKAVSLEEAKRKILELGEQNNSLGH-NLEEERNVNQK 710 Query: 374 SGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDT 433 + + + L+ D ++ + + ++ L + + ++E Sbjct: 711 LHSDLEHMKRHIEEKKKHLELSLDEERAKLLQNLEESSKTMKHLEETSLALTEELNELKI 770 Query: 434 XXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELND-E 492 +DTL+ +L + + + E++ + + E+ K+++ + E Sbjct: 771 RNEELAKVAEERDTLLK--KLTESEENNSLQALQIQNLEEEMVKTVQTLEETKRKIQELE 828 Query: 493 IKDVNVKDLIEKLKSAEEQIT----QLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFS 548 K+ +++ +E+ ++ +++T + I+ K++ + KL +QK ++ Sbjct: 829 EKNNSLQHSLEEERNVNQKLTTELEHVKRHIEEKKKDLESTLDEERAKL--LQKLEESSK 886 Query: 549 KVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENL 608 + + LTEEL+ L A++ EE+ L L D + +++ ++++NL Sbjct: 887 TMKHLEETGFALTEELNELKINNAKVAEERDTLVKKLTDSEETNSLQT------LKIQNL 940 Query: 609 AETRLKAISLLESQKFDLVQELHILQQKYDE-------VEDKLADISQLQSDQVCSEIKS 661 E + LE+++ + ++ L++K +EDK D + Q D+ S +K Sbjct: 941 EEEMRNLFASLENERKNSIKAGEELEEKEANLKKLKMLLEDKENDFVR-QLDEKESRLKK 999 Query: 662 VHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLT 721 + EE + +S+ KK L NL + Q+ DL+ K + L I+E DL Sbjct: 1000 I--EEMEEEISSLKKLLDEANNNLAVKNHQIEIYEADLKT-KNGQIEALSRKIEEYNDLI 1056 Query: 722 DKLEKMSAEKISELLAKINHEEQSKIQTQ-FGIDAKIQERDLYIENIESELSKYKSRICR 780 ++ + + +S +N+ ++K + ++ K+Q + L+K + + Sbjct: 1057 EERNEGFFKILSNFSEPLNNVRRNKDNKHLYNLEQKLQNFEQTFSLERENLAKILIYLKQ 1116 Query: 781 LEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRL----AVLMDHDRV 836 EE + +E+ + L R+ +L + E A S Y Q +E + RL LM+ Sbjct: 1117 FEEKHSALEEEKEELLRQITELRKQIVEVNSAQS-YVKQFEEEILRLREENVRLMEEQEK 1175 Query: 837 VEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTK- 895 ++ +LE+E N ++ + L EEN L + +++ N E ++ L++ E+ + Sbjct: 1176 FKQNVLELESRNTQVVSDSNFLSEENHGLLTEIEELKLK-NEEYETKHKNLLSQIENLER 1234 Query: 896 --YQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKN 953 Q+QL +LE +L + HE Q L++++ E++ I + E +++ + L K + Sbjct: 1235 ESNQSQLAELEKHLTELQHEKQ-LLLEEIDELKTTPINAANKSEDYVKEIENLRTKIVQY 1293 Query: 954 IEYVTQLEAQLQEYKNNIENLNMNVEELNK 983 + ++ Y+N ++ L E+LN+ Sbjct: 1294 KSLDLTNRSSIEFYENELQKLKNQNEKLNR 1323 Score = 75.4 bits (177), Expect = 1e-11 Identities = 184/918 (20%), Positives = 380/918 (41%), Gaps = 71/918 (7%) Query: 700 ENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQE 759 E E++ + Q + Q ++D+L+ S E I + + + + K++ Sbjct: 7 EKITEEVKSSPQRFQQLTQSVSDRLQNSSTS--DENFFSIAEDGFTNVSLVSPQENKMRR 64 Query: 760 R-DLYIENIESELSKYKS--RICRLEESIAVMEDRRYSLERKADQLGSYLQEK-QKAYSE 815 + I + S L +Y+S + L+ + + + QLG +E+ A+ + Sbjct: 65 NSNSSIASDVSFLPRYESFANMYHLQSDLDISASEIEDNASNSSQLGHLSKEQIYSAFQK 124 Query: 816 YTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQH 875 ++ + R L H + +E++ +++ E Q K + E + Q +L +Q Sbjct: 125 AQMRYHKYRGRYTDLAKHYKDLERENAKMKSVLVETQDKAIRRVTELKE-QCAL---EQK 180 Query: 876 YNALVEKANRTDLAESEST--KYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFN 933 A +E A R ++ E + QT++ L++ + + EIE+L N Sbjct: 181 AKAHLESALRDEIDEKQFKIESLQTKIELLQTPETENPDTLNKYLTDARVEIENL----N 236 Query: 934 TQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNL--ELIDK 991 +I+ + + K ++ +T LE ++ + + N+++ + NKM L EL+ K Sbjct: 237 QRIQEMKANSIIFQTKEQEYKAKITNLEKEIALFSEREKENNLSLAQ-NKMELHNELLSK 295 Query: 992 HVQ-KQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKL 1050 + +S + + L + E++ AL QK NN + + M +L Sbjct: 296 DAEISNLKKSLEALTGGTGKFENLQTQNTKLIEKLEALTQKCNNYENKLLKM-----EQL 350 Query: 1051 AQFTTKLENMEEEMQRVSKQLL----DSKQHNEELQILVREQDDQIKELKETKLTFEMNI 1106 + + +++E+Q + QL ++K+ L+ +RE+ + E KE +L + Sbjct: 351 RRENEENSRLKKEIQDIQGQLEGVREEAKKSLLSLETKIREKLAKEFEEKEERLRSDFR- 409 Query: 1107 PKTEGMIISSTIE----PMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSA 1162 K E + SS+ E M ++ + K + ++ + L E+S Sbjct: 410 KKIEEVSSSSSNEFNLLEMEEEIRKLRQVNDGILEQLTS-KTTKYDDLERNHLELIEESG 468 Query: 1163 KLNTELQECYTKIIQLETLNTELT---GHDVVNQEQINQLKSKLEQLNTENDNLLSTVAE 1219 +L +++ ++ L+ N GH N + + + ++L E D+LL Sbjct: 469 RLRSQIGGLEKELATLQNTNQAANLKLGHLEANARVLERTVEEYKRLEAERDDLLQEKKN 528 Query: 1220 LRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSST 1279 + ++R E L + L EH L + + K L++V+ Sbjct: 529 FMEDLEE--ERRINERLNLEVEQLRDEMVKKSDLEHSLEEERKVTQ-KLNTELENVKCHI 585 Query: 1280 QEETNKI-VTM-EQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXX 1337 +E+ + +T+ E+ L KL++ ++++L++ + ++ L+ +++E++A Sbjct: 586 EEKKKDLELTLDEEKGKLLQKLEESSVNMKHLEDTGLALSEELNSLK--LKNEELAKLAE 643 Query: 1338 XXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVND 1397 TE++ +Q + I N+ EE A+ K S N+ Sbjct: 644 ERDTLLKKL-------TESEETNSLQTRKIQNLEEEMAK-KAVSLEEAKRKILELGEQNN 695 Query: 1398 AEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKES 1457 + L H LE ++ + QK H + +R+ E + +L E+R + L +ES Sbjct: 696 S------LGHNLE-EERNVNQKLHS-DLEHMKRHIEEKKKHLELSLDEERAKLLQNLEES 747 Query: 1458 ELAILRLKMHENANHYETMQ-KESEIERVKLIEELNV---KITESVSLNKQVAELNKALE 1513 + L+ A E + K E K+ EE + K+TES N A + LE Sbjct: 748 SKTMKHLEETSLALTEELNELKIRNEELAKVAEERDTLLKKLTESEENNSLQALQIQNLE 807 Query: 1514 EEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQ-- 1571 EE+ KT +QT LE + +I L ++ +LQ+ + + QK + K+ +E+ Sbjct: 808 EEMVKT--VQT-LEETKRKIQELEEKNNSLQHSLEEERNVNQKLTTELEHVKRHIEEKKK 864 Query: 1572 -LDNTMNKELLDAVPRAE 1588 L++T+++E + + E Sbjct: 865 DLESTLDEERAKLLQKLE 882 Score = 68.1 bits (159), Expect = 2e-09 Identities = 145/710 (20%), Positives = 274/710 (38%), Gaps = 57/710 (8%) Query: 73 EHRKATAELLGRPFVPGISESLANTLKQKEILMEKIKQYKELSKRSSTTIVRXXXXXXXX 132 EH K E + + E A L+ E E K K L + S Sbjct: 716 EHMKRHIEEKKKHLELSLDEERAKLLQNLE---ESSKTMKHLEETSLALTEELNELKIRN 772 Query: 133 XXXXXXXQLGDVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQ--EKINEKDQIIEAKN 190 + D T E++N+L LQ++ + E + +Q E+ K Q +E KN Sbjct: 773 EELAKVAEERDTLLKKLTESEENNSLQALQIQ-NLEEEMVKTVQTLEETKRKIQELEEKN 831 Query: 191 KATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRI 250 + E K+ + + +++ +E+ +E+ +LL+ +E + Sbjct: 832 NSLQHSLEEERNVNQKLTTELEHVKRHIEEKKKD---LESTLDEERAKLLQKLEESSKTM 888 Query: 251 SSLEEANKLLEAARFEISLEHSKLAQELEQ--XXXXXXXXXXXXXXLAKQSIEPSCEE-- 306 LEE L E+ + ++K+A+E + L Q++E Sbjct: 889 KHLEETGFALTEELNELKINNAKVAEERDTLVKKLTDSEETNSLQTLKIQNLEEEMRNLF 948 Query: 307 -KTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKK 365 E E K S++ EL +K L+ L + + +L + K + ++ Sbjct: 949 ASLENERKNSIKAGE--ELEEKEANLKKLKMLLEDKENDFVRQLDEKESRLKKIEEMEEE 1006 Query: 366 GSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDK- 424 S L N +K+ ++ + D K +I L I+ N DL+++ Sbjct: 1007 ISSLKKLLDEANNNLAVKNHQIEI------YEADLKTKNGQIEALSRKIEEYN-DLIEER 1059 Query: 425 -EYVISEKDTXXXXXXXXXXGKD-----TLIAQLQ-LEHQQHMEGPSLIHVGTNTEDVNE 477 E KD L +LQ E +E +L + + E Sbjct: 1060 NEGFFKILSNFSEPLNNVRRNKDNKHLYNLEQKLQNFEQTFSLERENLAKILIYLKQFEE 1119 Query: 478 IAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEI-DAANKNMIKVKSNHKLK 536 E+ K+EL +I ++ K ++E + SA+ + Q +EI +N+ ++ K K Sbjct: 1120 KHSALEEEKEELLRQITELR-KQIVE-VNSAQSYVKQFEEEILRLREENVRLMEEQEKFK 1177 Query: 537 LKQMQKTIDNFSKVSDSN---KEIVRLTEELHHLSQKVAELEEEKGNL--QLHLVDYDSG 591 ++ N VSDSN +E L E+ L K E E + NL Q+ ++ +S Sbjct: 1178 QNVLELESRNTQVVSDSNFLSEENHGLLTEIEELKLKNEEYETKHKNLLSQIENLERESN 1237 Query: 592 RMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQ 651 + +++ K + E+++ + L+ I L++ + + + E+E+ I Q + Sbjct: 1238 QSQLAELEKHLTELQHEKQLLLEEIDELKTTPINAANK---SEDYVKEIENLRTKIVQYK 1294 Query: 652 SDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQL-YGTIKDLEN--DKEDIMN 708 S + + E ++ L ++L N KLD+ + +L N + E + N Sbjct: 1295 SLDLTNRSSIEFYENELQKLKNQNEKL-----NRKLDETLVTLNHCSELSNSTEIEYLKN 1349 Query: 709 KLQNYI--QENMDLTDKLE---KMSAEKISELLAKINHEEQSKIQTQFGI 753 L NY+ +E+M L + K ++ +LAK +++ + Q GI Sbjct: 1350 VLYNYMLGKESMVLARVIAAVCKFDPQQTELILAK--EQQKQTLLGQLGI 1397 >UniRef50_UPI00015A607A Cluster: UPI00015A607A related cluster; n=1; Danio rerio|Rep: UPI00015A607A UniRef100 entry - Danio rerio Length = 2332 Score = 148 bits (358), Expect = 1e-33 Identities = 283/1380 (20%), Positives = 592/1380 (42%), Gaps = 116/1380 (8%) Query: 248 VRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEK 307 +++ +L + +L+ EI + L +E Q L K + + E+K Sbjct: 738 MQVDTLTQTKDVLQG---EIQCLQTDLERETAQKERELQESKKRNTELEKLQTKSAAEQK 794 Query: 308 T-EIEEKGSL-EIANMTELTKKIEL-LEHLNCQ-IRQTNKELENKLATMGTESKAVSSPS 363 E+ +G+ E+ E K++ E LN + + + +E +N T ++K +S Sbjct: 795 AAELRLRGACDEVERWKERENKVQREKEELNQKFLERVERESQNLEITQREKAK-MSDLM 853 Query: 364 KKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKIN-KNEIAKLEMVIQSLNKDLV 422 KK I R+ K+K ++ + E+L + +K ++ + LE + L + + Sbjct: 854 KKKEDEIRRRGEDIEELKLKLQSNEKTIESLEIELQQKETLESRVETLEKLNTQLKEKKL 913 Query: 423 DKEYVISEKDTXXXXXXXXXXGKDTLIA-QLQLEHQQHMEGPSLIHVGTNTED-----VN 476 DK I E ++ K+ QL+ + + +E S I ++ V Sbjct: 914 DK---IRENESRQKKRDEQEREKEVRWRRQLEQKDEGLIELKSRIDELIGEKEHISLLVE 970 Query: 477 EIAKVQEQLKQELNDEIK--DVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHK 534 E K EQL+ L+ E + ++ +K+ E+L+ EQI+Q+ + K + +++ N K Sbjct: 971 EREKDIEQLQSTLSTEKRALELRLKEKNEQLELLNEQISQIKEREIENQKELDRMQENLK 1030 Query: 535 LKLKQMQKTIDN----FSKVSDSNKEIVRLTEELHHLSQKV-AELEEEKGNL-QLHLVDY 588 + KQ+++ +D+ + V +E++ EE QK+ AE E+ + QL L Sbjct: 1031 EQEKQLKRELDHLNIKMAGVIQEKEELLERIEEQRMFEQKLKAEHAEKDVEVRQLKLKIE 1090 Query: 589 DSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADIS 648 + + IE D +M + E+L + +LL + + LQQK E D+L Sbjct: 1091 ELNQEIEQDRRIRMEQQEDLEQ----QTALLRDAEEEARTLKKTLQQKDKEERDRL---H 1143 Query: 649 QLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKED--I 706 + ++ + K E++ + +S +E+ +E ++ QL G + L E+ + Sbjct: 1144 HEEKEKTLLKEKLHEAEQRNIKVLSSLQEIETTLEK---ERYQLRGKEERLMECNEELFL 1200 Query: 707 MNKLQNYIQENMDLTDKLEKMSAEKISELLAKINH--EEQSKIQTQF-GIDAKIQERDLY 763 + + ++ +E+++ +KL +++ L K++ EE+ ++ ++Q + Sbjct: 1201 IKRERDQEKESIEELNKLIGEQGKEVKTLRGKLDERLEEEGRLSKLLQNQRVEVQVLESR 1260 Query: 764 IENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYT-IQEDE 822 ENIE E + K + ++EE +E + + ++L L+++ ++ I E+E Sbjct: 1261 AENIEEEKQQLKRSLSQIEEEKRHLETQLTDEKVDKERLRVRLEDQATEVTKLNKILEEE 1320 Query: 823 LVNRLAVLMDHDRVVEKQLLEIEHEN----KELQKKNQILLE-ENQNLQISLSDMQQHYN 877 +L+ L+ + R VE Q+ E +N K+L K++ +E E L+ L+D + Sbjct: 1321 --RKLSQLLQNSR-VEAQMFESRAQNTEEEKQLLKRSLSQIEREKSRLETQLTDEKMDKE 1377 Query: 878 ALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFN---- 933 L + D ++ + ++ + E L ++ + + E++E+E Sbjct: 1378 KLKARLEDQDKEVTKLKEKMNEILEEERKLSQLLQNSRVEAQMLESRAENIEVEKQQLKR 1437 Query: 934 --TQIESAIR--DKKVLNEKYEKNIEYVTQ-LEAQLQEYKNNIENLNMNVEELNK----M 984 TQIE R ++ +EK +KN LE++ + + + L ++ ++ K + Sbjct: 1438 SLTQIEEEKRHLGTQLTDEKMDKNSRVEAHILESRTENIEEEKQQLTRSLTQIEKEKRHL 1497 Query: 985 NLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVS 1044 +L D+ + K++ ++ + E+ KL L + EE L+Q + N++V + S Sbjct: 1498 ETQLTDEKMDKERLRA--RLKDQATEVTKLKEKLNEMIEEERKLSQLLQNSRVEAQMLES 1555 Query: 1045 DYESKL---AQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLT 1101 E+ + Q L +EEE + + QL D K E L+ + +Q ++ +LK L Sbjct: 1556 RAENTIEEKQQLKRVLSQVEEEKRLLETQLTDEKIDRERLKARLEDQATEVTKLKTENLE 1615 Query: 1102 FEMNIPK-------TEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXL---KVQEEEEFI 1151 E K E + + + D + L K+ E+ Sbjct: 1616 EEKQQLKRSLTQIEEEKRCLETQLTDEKIDRERLRARLEDFQKDQQILFEEKMGRAEKLG 1675 Query: 1152 QERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTEND 1211 L+EQ L+ EL+ K ++E L E ++++ LK LE+ + E + Sbjct: 1676 SRVRELEEQRDHLSAELRR---KEREMEVLRDETLRER--REKEMATLKELLEESHREGE 1730 Query: 1212 NLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQR----EADFQKTEHELRVQLSAFESK 1267 L S + E + + + ++ G ++A + + L + E Q+ E L++Q+ + K Sbjct: 1731 RLRSMMQERKDELVRSREE-GIKVAHIEAKDLQLKVQMLEKQKQELETTLQLQVEQLKKK 1789 Query: 1268 YEQ-LLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSE 1326 E+ + + Q ++E + + L N+ +D L+E N E L+ E Sbjct: 1790 NEEGMQEKEQLQQRQEKLEAERTKDAEELSNRFRDLRLEADRLREDRIREKNNWEELKRE 1849 Query: 1327 IEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXX 1386 ++++ A +++ + Y+ + +S + +++ Sbjct: 1850 NKEKQNAL-EELELLRKTLMEKEKEMKLVKEKYENEKRRSERFQQGDEQNVRQIELVSER 1908 Query: 1387 XXXXXXXRVNDAEAKVLELTHQLELKD-----SEIYQKTHEYTITLTQRNDEFENVRQQL 1441 + E E + +L L+D + +K E TL + N E+ + +L Sbjct: 1909 LRDKETELESIREKAYKEQSARLRLQDQFEDEKRVTKKLREKLETLEKINAEYRS-HVKL 1967 Query: 1442 VEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERV-KLIEELNVKI--TES 1498 +E + +DLT +K+ E+ LR+K ET+Q +EI+R+ L++ N+K TE+ Sbjct: 1968 LEADTLRKDLT-KKDQEIRRLRIKA-------ETLQ--TEIDRLHSLLKNGNMKTGPTEN 2017 Query: 1499 VSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLN---DEITNLQNMVRASSSKIQ 1555 +++ +++ L E+ E L +++E+ L +E++ ++ VR + K + Sbjct: 2018 EDWDREKQQVSTILLEK----EERDRLLREKDVEVYALKERAEEMSKDRDRVRIALEKTE 2073 Score = 132 bits (320), Expect = 6e-29 Identities = 243/1164 (20%), Positives = 495/1164 (42%), Gaps = 122/1164 (10%) Query: 508 AEEQITQLNDEIDAANKNMIKVKSNH-KLKLKQMQKTIDNF-SKVSDSNKEIVRLTEELH 565 A E++ LN+ + A +K + V+S + ++ + Q I F ++ + ++E+ ++ E+H Sbjct: 546 ALEKMAALNEAL-AKDKRELGVRSLQLETEVAEAQAQIQAFGTETAGLHRELKAMSLEVH 604 Query: 566 HLSQKVAELEEE--------KGNLQLHLVDYDSGRMIESDVYKK----MIEMENLAETRL 613 L ++ ELE E + D + S++ ++ M E++++ L Sbjct: 605 ELRERERELENELELEREDRQREQTARTEDKSTDEQKISELTEQCSTVMKELQSVKVELL 664 Query: 614 KAISL---LESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQ----VCSEIKSVHLEE 666 KA L E ++ DL++E L+ +E + +++Q++ + VC + + +E Sbjct: 665 KAAELQRRAERERDDLMRESQRLEDTVCTLEREKEELAQVKEELRGVVVCLQKQMAQAQE 724 Query: 667 QIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEK 726 Q L +L + ++ L K+ L G I+ L+ D E + + +QE+ +LEK Sbjct: 725 QTSGLELKCIQLQMQVDTLTQTKDVLQGEIQCLQTDLERETAQKERELQESKKRNTELEK 784 Query: 727 MSAEKISE-------LLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESE---LSKYKS 776 + + +E L + E+ K + K + ++E +E E L + Sbjct: 785 LQTKSAAEQKAAELRLRGACDEVERWKERENKVQREKEELNQKFLERVERESQNLEITQR 844 Query: 777 RICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTI---QEDELVNRLAVLMDH 833 ++ + + ED ++L LQ +K I Q++ L +R+ L Sbjct: 845 EKAKMSDLMKKKEDEIRRRGEDIEELKLKLQSNEKTIESLEIELQQKETLESRVETLEKL 904 Query: 834 DRVVEKQLLEIEHENKELQKKNQILLEENQNLQIS-LSDMQQHYNALVEKANRTD--LAE 890 + ++++ L+ EN+ QKK E+ + ++ ++Q L+E +R D + E Sbjct: 905 NTQLKEKKLDKIRENESRQKKRD---EQEREKEVRWRRQLEQKDEGLIELKSRIDELIGE 961 Query: 891 SE--STKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNE 948 E S + + +D+E ++ E + L ++ K++ E LE+ N QI S I+++++ N+ Sbjct: 962 KEHISLLVEEREKDIEQLQSTLSTEKRALELRLKEKNEQLEL-LNEQI-SQIKEREIENQ 1019 Query: 949 KYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYI 1008 K ++ L+ Q ++ K +++LN+ + + + EL+++ +++ + E Sbjct: 1020 KELDRMQ--ENLKEQEKQLKRELDHLNIKMAGVIQEKEELLERIEEQRMFEQKLKAEHAE 1077 Query: 1009 NEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVS 1068 ++ LK K EE LNQ+I + M D E Q T L + EEE + + Sbjct: 1078 KDVEVRQ--LKLKIEE---LNQEIEQDRRIRMEQQEDLE----QQTALLRDAEEEARTLK 1128 Query: 1069 KQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGM-IISSTIEPMSDDANN 1127 K L ++ EE L E+ ++ ++ + NI + I +T+E Sbjct: 1129 KTL--QQKDKEERDRLHHEEKEKTLLKEKLHEAEQRNIKVLSSLQEIETTLEKERYQLRG 1186 Query: 1128 VDXXXXXXXXXXXXLKVQ--EEEEFIQE-RSVLQEQS-------AKLNTELQE--CYTKI 1175 + +K + +E+E I+E ++ EQ KL+ L+E +K+ Sbjct: 1187 KEERLMECNEELFLIKRERDQEKESIEELNKLIGEQGKEVKTLRGKLDERLEEEGRLSKL 1246 Query: 1176 IQLETLNTELTGHDVVN-QEQINQLKSKLEQLNTENDNLLSTVAEL---RSSISSAVDQR 1231 +Q + + ++ N +E+ QLK L Q+ E +L + + + + + ++ + Sbjct: 1247 LQNQRVEVQVLESRAENIEEEKQQLKRSLSQIEEEKRHLETQLTDEKVDKERLRVRLEDQ 1306 Query: 1232 GFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYE------QLLDSVQSSTQEETNK 1285 E+ +L K + + E + RV+ FES+ + QLL S + E ++ Sbjct: 1307 ATEVTKLNK--ILEEERKLSQLLQNSRVEAQMFESRAQNTEEEKQLLKRSLSQIEREKSR 1364 Query: 1286 I---VTMEQV--TSLQNKLQDKEEHLRNLQEKYADVINQ-----------------IEIL 1323 + +T E++ L+ +L+D+++ + L+EK +++ + +E Sbjct: 1365 LETQLTDEKMDKEKLKARLEDQDKEVTKLKEKMNEILEEERKLSQLLQNSRVEAQMLESR 1424 Query: 1324 RSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSIL-----NINEENAQLK 1378 IE EK L E E IL NI EE QL Sbjct: 1425 AENIEVEKQQLKRSLTQIEEEKRHLGTQLTDEKMDKNSRVEAHILESRTENIEEEKQQLT 1484 Query: 1379 KSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEI---YQKTHEYTITLTQRNDEFE 1435 +S ++ D + L +L+ + +E+ +K +E + + + Sbjct: 1485 RSLTQIEKEKRHLETQLTDEKMDKERLRARLKDQATEVTKLKEKLNEMIEEERKLSQLLQ 1544 Query: 1436 NVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKI 1495 N R + E R E+ T E++ +L + ++ E ET + +I+R +L L + Sbjct: 1545 NSRVEAQMLESRAEN-TIEEKQQLKRVLSQVEEEKRLLETQLTDEKIDRERLKARLEDQA 1603 Query: 1496 TESVSL-NKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKI 1554 TE L + + E + L+ + + E + LE Q L DE + + + RA Sbjct: 1604 TEVTKLKTENLEEEKQQLKRSLTQIEEEKRCLETQ------LTDEKIDRERL-RARLEDF 1656 Query: 1555 QKHVSFASDTKQGRDEQLDNTMNK 1578 QK + K GR E+L + + + Sbjct: 1657 QKDQQILFEEKMGRAEKLGSRVRE 1680 Score = 105 bits (251), Expect = 1e-20 Identities = 185/880 (21%), Positives = 375/880 (42%), Gaps = 59/880 (6%) Query: 246 KDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCE 305 +D S+EE NKL+ E+ KL + LE+ + Q +E E Sbjct: 1205 RDQEKESIEELNKLIGEQGKEVKTLRGKLDERLEEEGRLSKLLQNQRVEV--QVLESRAE 1262 Query: 306 EKTEIEEKGSLEIANMTELTKKIEL-LEHLNCQIRQTNKELENKLATMGTESKAVSSPSK 364 E +++ ++ + E + +E L + LE++ AT T+ + + Sbjct: 1263 NIEEEKQQLKRSLSQIEEEKRHLETQLTDEKVDKERLRVRLEDQ-ATEVTKLNKILEEER 1321 Query: 365 KGSPLI--SRKSGRNTASKMKS--PWSQLSSETLNQ-DTDKKINKNEIAKLEMVIQSLNK 419 K S L+ SR + S+ ++ QL +L+Q + +K + ++ +M + L Sbjct: 1322 KLSQLLQNSRVEAQMFESRAQNTEEEKQLLKRSLSQIEREKSRLETQLTDEKMDKEKLKA 1381 Query: 420 DLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTN--TEDVNE 477 L D++ +++ L+ ++E Q I V + + Sbjct: 1382 RLEDQDKEVTKLKEKMNEILEEERKLSQLLQNSRVEAQMLESRAENIEVEKQQLKRSLTQ 1441 Query: 478 IAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKL 537 I + + L +L DE D N + L+S E I + ++ + + K K + + +L Sbjct: 1442 IEEEKRHLGTQLTDEKMDKNSRVEAHILESRTENIEEEKQQLTRSLTQIEKEKRHLETQL 1501 Query: 538 KQMQKTIDNF-SKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIES 596 + + +++ D E+ +L E+L+ + +EEE+ QL +M+ES Sbjct: 1502 TDEKMDKERLRARLKDQATEVTKLKEKLNEM------IEEERKLSQLLQNSRVEAQMLES 1555 Query: 597 DVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYD------EVEDKLADISQL 650 + E + L + +S +E +K + E + +K D +ED+ ++++L Sbjct: 1556 RAENTIEEKQQLK----RVLSQVEEEK--RLLETQLTDEKIDRERLKARLEDQATEVTKL 1609 Query: 651 QSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDK----EDI 706 +++ + E + L+ + + K+ L + + K+D+E+L ++D + D+ E+ Sbjct: 1610 KTENL--EEEKQQLKRSLTQIEEEKRCLETQLTDEKIDRERLRARLEDFQKDQQILFEEK 1667 Query: 707 MNKLQNYIQENMDLTDKLEKMSAE-KISELLAKINHEE---QSKIQTQFGIDAKIQERDL 762 M + + +L ++ + +SAE + E ++ +E + + + + ++E Sbjct: 1668 MGRAEKLGSRVRELEEQRDHLSAELRRKEREMEVLRDETLRERREKEMATLKELLEESHR 1727 Query: 763 YIENIESELSKYKSRICR-LEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQED 821 E + S + + K + R EE I V +E K QL + EKQK E T+Q Sbjct: 1728 EGERLRSMMQERKDELVRSREEGIKVAH-----IEAKDLQLKVQMLEKQKQELETTLQLQ 1782 Query: 822 ELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVE 881 V +L + + + EK+ L+ E E ++ N+ + L + + + E Sbjct: 1783 --VEQLK-KKNEEGMQEKEQLQQRQEKLEAERTKDAEELSNRFRDLRLEADRLREDRIRE 1839 Query: 882 KANRTDLAESESTKYQTQLRDLESNLKRITH-EHQTLIVQKKKEIEDLEIE-FNTQIESA 939 K N +L + E+ + Q L +LE K + E + +V++K E E E F E Sbjct: 1840 KNNWEEL-KRENKEKQNALEELELLRKTLMEKEKEMKLVKEKYENEKRRSERFQQGDEQN 1898 Query: 940 IRDKKVLNEKY-EKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQT 998 +R ++++E+ +K E + E +E + L E+ ++ +L +K ++ Sbjct: 1899 VRQIELVSERLRDKETELESIREKAYKEQSARL-RLQDQFEDEKRVTKKLREKLETLEKI 1957 Query: 999 QSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYES-KLAQFTTKL 1057 + + + E + L L +KD+EI L K Q + S ++ + T+ Sbjct: 1958 NAEYRSHVKLLEADTLRKDLTKKDQEIRRLRIKAETLQTEIDRLHSLLKNGNMKTGPTEN 2017 Query: 1058 ENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKE 1097 E+ + E Q+VS LL+ EE L+RE+D ++ LKE Sbjct: 2018 EDWDREKQQVSTILLE----KEERDRLLREKDVEVYALKE 2053 Score = 61.3 bits (142), Expect = 2e-07 Identities = 138/756 (18%), Positives = 313/756 (41%), Gaps = 55/756 (7%) Query: 146 HLSNTIKEKDNALSVLQVKMKIMETTILDLQEKIN---EKDQIIEAKNKATTXXXXXXXX 202 HL + ++ L+ ++K T + L+EK+N E+++ + + + Sbjct: 1496 HLETQLTDEKMDKERLRARLKDQATEVTKLKEKLNEMIEEERKLSQLLQNSRVEAQMLES 1555 Query: 203 XXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEK---QRLLKDIESKDVRISSLEEANKL 259 + K+ +++++E +E + DEK +RL +E + ++ L+ N Sbjct: 1556 RAENTIEEKQQLKRVLSQVEEEKRLLETQLTDEKIDRERLKARLEDQATEVTKLKTEN-- 1613 Query: 260 LEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIA 319 LE + ++ +++ +E L + + +++ EEK Sbjct: 1614 LEEEKQQLKRSLTQIEEEKRCLETQLTDEKIDRERLRARLEDFQKDQQILFEEKMGRAEK 1673 Query: 320 NMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTA 379 + + + E +HL+ ++R+ +E+E E + + K S + G Sbjct: 1674 LGSRVRELEEQRDHLSAELRRKEREMEVLRDETLRERREKEMATLKELLEESHREGERLR 1733 Query: 380 SKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVIS-EKDTXXXXX 438 S M+ +L +++ K+ E L++ +Q L K + E + + + Sbjct: 1734 SMMQERKDEL---VRSREEGIKVAHIEAKDLQLKVQMLEKQKQELETTLQLQVEQLKKKN 1790 Query: 439 XXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKD-VN 497 K+ QLQ + Q+ +E T+D E++ L+ E + +D + Sbjct: 1791 EEGMQEKE----QLQ-QRQEKLE-------AERTKDAEELSNRFRDLRLEADRLREDRIR 1838 Query: 498 VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKL---KLKQMQKTIDNFSKVSDSN 554 K+ E+LK ++ +E++ K +++ + KL K + ++ + F + + N Sbjct: 1839 EKNNWEELKRENKEKQNALEELELLRKTLMEKEKEMKLVKEKYENEKRRSERFQQGDEQN 1898 Query: 555 KEIVRLTEELHHLSQKVAELE--EEKG----NLQLHLVD-YDSGRMIESDVYKKMIEMEN 607 + L E L K ELE EK + +L L D ++ + + + +K+ +E Sbjct: 1899 VRQIELVSE--RLRDKETELESIREKAYKEQSARLRLQDQFEDEKRVTKKLREKLETLEK 1956 Query: 608 LAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQ 667 + + LLE+ L ++L Q+ + K A+ Q + D++ S +K+ +++ Sbjct: 1957 INAEYRSHVKLLEAD--TLRKDLTKKDQEIRRLRIK-AETLQTEIDRLHSLLKNGNMKTG 2013 Query: 668 IDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKM 727 +E V + L+KE+ +++ + + + + + ++ + LEK Sbjct: 2014 PTENEDWDREKQQV-STILLEKEERDRLLREKDVEVYALKERAEEMSKDRDRVRIALEKT 2072 Query: 728 SAEKISELLAKINHEEQSKIQTQFGIDAKIQE------RDLYIENI-ESELSKYKSRICR 780 A I ++ H+E + QT G D + + + YIE+ E ++++ +CR Sbjct: 2073 EAMLI-YYKERLGHQEHKRKQT--GGDISLMQIVYFLFQTQYIEHASEIQVNRECLVLCR 2129 Query: 781 L--EESIAVMEDRRYSLERKADQLGSYLQ--EKQKAYSEYTIQEDELVNRLAVLMDHDRV 836 + + ++ +R ++ L Y + +K ++ E + RL+ + Sbjct: 2130 VCSNQQASMGSCKRSFYKQHRLTLWPYHPPGDLEKVSADELDTESAVHGRLSAMQQAVAQ 2189 Query: 837 VEKQLLEIEHENKELQKKNQILLEENQNLQISLSDM 872 +E Q +E +N L+KK + L E Q+L+ +L+ + Sbjct: 2190 LEVQQNLLEKKNSHLEKKIERLRTERQHLRETLTQL 2225 >UniRef50_O76329 Cluster: Interaptin; n=2; Dictyostelium discoideum|Rep: Interaptin - Dictyostelium discoideum (Slime mold) Length = 1738 Score = 147 bits (357), Expect = 2e-33 Identities = 242/1168 (20%), Positives = 524/1168 (44%), Gaps = 123/1168 (10%) Query: 471 NTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAE-EQITQLN-----DEIDAANK 524 NT + E ++V E++ +++ + K V V+ ++E K E E+I ++ D+I+ Sbjct: 367 NTIIIAEESRVIEKIVEKIIEVEKIVEVEKIVEVEKIVEVEKIVEVEKIVKVDDIEKLTN 426 Query: 525 NMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLH 584 ++ + ++ K ++ ++ + + ++V + +L + +EL E+ G L Sbjct: 427 LQDQLTEQQQQYQEKSLKLVNLELELQEKSNQLVDKSNQLSTMQATNSELMEKIGGLMND 486 Query: 585 LVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKL 644 L D + + E D +++E+ E LK + + LQ +Y ++ Sbjct: 487 LTDIPTQDIKEKDEIIANLKIES--EKNLKCFQ----------DDFNALQSRYSLTIEQT 534 Query: 645 ADISQLQSDQVCSEIKSVHLEEQIDALSASKKELA---LVIENLKLDKEQLYGTIKDLEN 701 + + Q + Q+ +E++ ++ I+ ++S + LA VI+ L +K+ + ++D ++ Sbjct: 535 SQL-QDRIKQLINELQERD-DKFIEFTNSSNQSLADNQRVIDQLTNEKQSITLQLQDQQD 592 Query: 702 DKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERD 761 KE + + E L +++ ++ I E K N+ +Q + TQ ++ QE Sbjct: 593 IKE------KEFQFEKQQLLSQIDSITTN-IQEYQDKFNNLQQ-EFNTQQTLNQ--QETH 642 Query: 762 LYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQED 821 + + + Y + +L+ I +D + E+ QL +E +K ++ Q+D Sbjct: 643 RLTQQLYQINTDYNEKQTQLQSEI---KDNQTINEQLNKQLSEKDKEIEKLSNQQEQQQD 699 Query: 822 ELVNRLAV-LMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALV 880 E +N L + + + D ++E+ ++ EN +L K Q LL E +N ++ N+ Sbjct: 700 EKINNLLLEIKEKDCLIERINQQLL-ENIDLNSKYQQLLLEFENFKL---------NSSK 749 Query: 881 EKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAI 940 EK N+ + +S+ + QL D + ++ + Q K++ + Q++S I Sbjct: 750 EKENQLNELQSKQDERFNQLNDEKLEKEKQLQSIEDEFNQYKQQQLSSNSNIDQQLQSTI 809 Query: 941 RDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQ--KQQT 998 + L E+ E N + + E QLQ+ + + LN ++ ++ LEL++K ++ +Q+ Sbjct: 810 IELSELKEQKELNDSKLIEKEKQLQQLQQEFDQLNEKNQKDHQDQLELLEKQLKQLQQEY 869 Query: 999 QSPDYTEQYI-NEINKLNAL----LKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQF 1053 + T Q I N++N+ N + L +K++E++ L ++N Q+ + SK Sbjct: 870 DQLNETNQSIENQLNQQNLINKENLNEKEQELLKLQNQLNQ-QIEKIQFDQQEFSKQNSI 928 Query: 1054 TTKLENMEEE----MQRVSKQLLDSKQHNEELQILVREQDDQIKELKETK-LTFEMN--I 1106 +L N + E +Q+ QL + N+E ++++D I++ + K + E+N I Sbjct: 929 NIELVNEKNEKLIQLQQDYDQLKQQNRSNDE-----KDENDLIEKENQLKSIQNELNQLI 983 Query: 1107 PKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNT 1166 K E ++ S ++ L+ Q E+ Q+ + L E+ +LN Sbjct: 984 EKNESDHKEQQLKQQS-----IENDLIEKENQIQQLQSQLNEQRQQQSNQLSEKDQQLNQ 1038 Query: 1167 ELQECYTKIIQLE-TLNTELTGHDVVNQE-QINQLKSKLEQLNTENDNLLSTVAELRSSI 1224 +++ + Q E L + +D+ +E QI QL+S+L + + N LS E + Sbjct: 1039 LIEK--NQFDQKEQQLKQQSIENDLFEKENQIQQLQSQLNEQRQQQSNQLS---EKDQQL 1093 Query: 1225 SSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETN 1284 + +++ + E Q L Q+ + E E ++Q + ++ L QS + + Sbjct: 1094 NQLIEKNESDQKE---QQLKQQSIENDLIEKENQIQQLQLQLNEQRQL---QSEVSIDND 1147 Query: 1285 KIVTME-QVTSLQN---KLQD-KEEHLRNLQEKYADVINQIEILRSEIEDEK----VAFX 1335 KI+ +E Q+ Q+ KL D K++ + LQ+K + +Q+++ ++ +++K + Sbjct: 1148 KILELEKQLKQCQSDLLKLNDEKQQQDKQLQDKQIE-FDQLQLTFNQFKNDKDSQFIQLQ 1206 Query: 1336 XXXXXXXXXXXXXXXDLRTENQ-SYKQMQE--QSILNINEENAQLKKSSXXXXXXXXXXX 1392 L+ ENQ KQ+ E + + +I EN + +K Sbjct: 1207 DDQKQQLQSIQQDLNQLKQENQEKEKQLSEKDEKLQSIQFENQEKEKQLSEKDEKLQSIQ 1266 Query: 1393 XRVNDAEAKVLELTHQLELKD----------SEIYQKTHEYTITLTQRNDEFENVRQQLV 1442 +N + E Q KD +++ Q+ E L++++++ ++++Q L Sbjct: 1267 QNLNQLNDENQEKVKQFSEKDEKLQSIQQDLNQLKQENQEKEKQLSEKDEKLQSIQQDLN 1326 Query: 1443 EY-EKRIEDLTYEKESELAILRLKMHENANHYETM--------QKESEIERVKLIEELNV 1493 + + +I+ KE E +L+L+ N + + +KE++++++K E+N Sbjct: 1327 QLNDDQIKKNEKLKEKEEQLLKLQQDFNDQQSQQLKQLEEKLSEKENQLQQLKQENEIN- 1385 Query: 1494 KITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSK 1553 ++ +Q E+ + L++++ K + + N E EI L EI L+ S+ Sbjct: 1386 ----QLNQQQQSNEIIQQLKDQLLKQQQQEQQENNNEKEIERLIQEIEQLKQQQEIDQSE 1441 Query: 1554 IQKHVSFASDTKQGRDEQLDNTMNKELL 1581 + + T Q +QL + +K+ L Sbjct: 1442 L-SNKEIKIQTTQQEFDQLSHNRSKDQL 1468 Score = 142 bits (344), Expect = 7e-32 Identities = 237/1213 (19%), Positives = 528/1213 (43%), Gaps = 109/1213 (8%) Query: 144 VTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKI----NEKDQIIEAKNKATTXXXXX 199 + +L ++EK N L ++ M+ T +L EKI N+ I K Sbjct: 445 LVNLELELQEKSNQLVDKSNQLSTMQATNSELMEKIGGLMNDLTDIPTQDIKEKDEIIAN 504 Query: 200 XXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVR-ISSLEEANK 258 +D + I ++ +D ++L+ +++ +D + I +N+ Sbjct: 505 LKIESEKNLKCFQDDFNALQSRYSLTIEQTSQLQDRIKQLINELQERDDKFIEFTNSSNQ 564 Query: 259 LL---EAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEK-G 314 L + +++ E + +L+ I+ E ++K Sbjct: 565 SLADNQRVIDQLTNEKQSITLQLQDQQDIKEKEFQFEKQQLLSQIDSITTNIQEYQDKFN 624 Query: 315 SLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKS 374 +L+ T+ T + L Q+ Q N + K + +E K + I+ + Sbjct: 625 NLQQEFNTQQTLNQQETHRLTQQLYQINTDYNEKQTQLQSEI--------KDNQTINEQL 676 Query: 375 GRNTASKMKSPWSQLSSETLNQDTDKKINK--NEIAKLEMVIQSLNKDLVDKEYVISEKD 432 + + K K +LS++ Q D+KIN EI + + +I+ +N+ L++ + S+ Sbjct: 677 NKQLSEKDKE-IEKLSNQQ-EQQQDEKINNLLLEIKEKDCLIERINQQLLENIDLNSK-- 732 Query: 433 TXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDE 492 QL LE E L +NE+ Q++ +LNDE Sbjct: 733 ----------------YQQLLLE----FENFKLNSSKEKENQLNELQSKQDERFNQLNDE 772 Query: 493 IKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTID-NFSKVS 551 + ++L+S E++ Q + ++N N+ + + ++L ++++ + N SK+ Sbjct: 773 KLEKE-----KQLQSIEDEFNQYKQQQLSSNSNIDQQLQSTIIELSELKEQKELNDSKLI 827 Query: 552 DSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAET 611 + K++ +L +E L++K + ++ QL L++ ++ + Y ++ E E Sbjct: 828 EKEKQLQQLQQEFDQLNEKNQKDHQD----QLELLEKQLKQLQQE--YDQLNETNQSIEN 881 Query: 612 RLKAISLLESQKF-DLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDA 670 +L +L+ + + QEL LQ + ++ +K+ Q S Q I+ V+ E+ + Sbjct: 882 QLNQQNLINKENLNEKEQELLKLQNQLNQQIEKIQFDQQEFSKQNSINIELVN--EKNEK 939 Query: 671 LSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAE 730 L +++ + + + + E+ + + EN + I N+L I++N + K +++ + Sbjct: 940 LIQLQQDYDQLKQQNRSNDEKDENDLIEKENQLKSIQNELNQLIEKN-ESDHKEQQLKQQ 998 Query: 731 KI-SELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESI--AV 787 I ++L+ K N +Q +Q+Q + Q L ++ + K++ + E+ + Sbjct: 999 SIENDLIEKENQIQQ--LQSQLNEQRQQQSNQLSEKDQQLNQLIEKNQFDQKEQQLKQQS 1056 Query: 788 MEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHE 847 +E+ + E + QL S L E+++ S ++D+ +N+L + D+ E+QL + E Sbjct: 1057 IENDLFEKENQIQQLQSQLNEQRQQQSNQLSEKDQQLNQLIEKNESDQ-KEQQLKQQSIE 1115 Query: 848 NKELQKKNQI-----LLEENQNLQISLSDMQQHYNALVE--KANRTDLAESESTKYQ--T 898 N ++K+NQI L E + LQ +S L + K ++DL + K Q Sbjct: 1116 NDLIEKENQIQQLQLQLNEQRQLQSEVSIDNDKILELEKQLKQCQSDLLKLNDEKQQQDK 1175 Query: 899 QLRD-------LESNLKRITHEHQTLIVQ----KKKEIEDLEIEFNTQIESAIRDKKVLN 947 QL+D L+ + ++ + +Q +K++++ ++ + N + +K L+ Sbjct: 1176 QLQDKQIEFDQLQLTFNQFKNDKDSQFIQLQDDQKQQLQSIQQDLNQLKQENQEKEKQLS 1235 Query: 948 EKYEK--NIEYVTQ-LEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYT 1004 EK EK +I++ Q E QL E ++++ N+ +LN N E + KQ ++ + Sbjct: 1236 EKDEKLQSIQFENQEKEKQLSEKDEKLQSIQQNLNQLNDENQEKV-----KQFSEKDEKL 1290 Query: 1005 EQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEM 1064 + ++N+L ++K++++ ++K+ + Q + D K KL+ EE++ Sbjct: 1291 QSIQQDLNQLKQENQEKEKQLSEKDEKLQSIQQDLNQLNDDQIKK----NEKLKEKEEQL 1346 Query: 1065 QRVSKQLLDSK-QHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSD 1123 ++ + D + Q ++L+ + E+++Q+++LK+ ++N + II + + Sbjct: 1347 LKLQQDFNDQQSQQLKQLEEKLSEKENQLQQLKQENEINQLNQQQQSNEIIQQLKDQLLK 1406 Query: 1124 DANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNT 1183 +QE E+ Q++ + Q + + ++Q + QL + Sbjct: 1407 QQQQEQQENNNEKEIERL--IQEIEQLKQQQEIDQSELSNKEIKIQTTQQEFDQLSHNRS 1464 Query: 1184 ELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGF---EIAELWK 1240 + D ++ +Q+ Q +L+Q + D+ V + R ++ ++Q ++ +L K Sbjct: 1465 K----DQLHLQQLQQELDQLKQSFDDQDHQFKKVIDERYNLQLQLEQSTLSNNQLDQLLK 1520 Query: 1241 QHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTME-QVTSLQNKL 1299 + L E D + + + LS S + L + + E N I T+E ++T + L Sbjct: 1521 EKLKPLELDSNEKQKTIDDLLSNI-SNLQISLQNDKDLISERNNSIKTLESRITQQLSLL 1579 Query: 1300 QDKEEHLRNLQEK 1312 +K+ +++LQ++ Sbjct: 1580 DEKDNLIKDLQQQ 1592 Score = 132 bits (320), Expect = 6e-29 Identities = 215/1167 (18%), Positives = 508/1167 (43%), Gaps = 87/1167 (7%) Query: 169 ETTILD-LQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIA 227 E+ +++ + EKI E ++I+E + D +++T +Q+ Sbjct: 374 ESRVIEKIVEKIIEVEKIVEVEKIVEVEKIVEVEKIVEVEKIVKVDDIEKLTNLQDQLTE 433 Query: 228 MEAEWKDEKQRLLK-DIESKDVRISSLEEANKL--LEAARFEISLEHSKLAQELEQXXXX 284 + +++++ +L+ ++E ++ ++++N+L ++A E+ + L +L Sbjct: 434 QQQQYQEKSLKLVNLELELQEKSNQLVDKSNQLSTMQATNSELMEKIGGLMNDLTDIPTQ 493 Query: 285 XXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKE 344 +A IE K ++ +L+ + + +L + + I + + Sbjct: 494 DIKEKDEI--IANLKIESEKNLKCFQDDFNALQSRYSLTIEQTSQLQDRIKQLINELQER 551 Query: 345 LENKLATMGTESKAVSSPSKKGSPLISRKSG----RNTASKMKSPWSQLSSETLNQDTDK 400 + + + +++++ + L + K +K Q + L D Sbjct: 552 DDKFIEFTNSSNQSLADNQRVIDQLTNEKQSITLQLQDQQDIKEKEFQFEKQQLLSQIDS 611 Query: 401 KINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHM 460 I N I + + +L ++ + + +++++T D Q QL Q + Sbjct: 612 -ITTN-IQEYQDKFNNLQQEF-NTQQTLNQQETHRLTQQLYQINTDYNEKQTQL--QSEI 666 Query: 461 EGPSLIHVGTN---TEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLND 517 + I+ N +E EI K+ Q +Q+ +++I ++ + ++ EK E QL + Sbjct: 667 KDNQTINEQLNKQLSEKDKEIEKLSNQQEQQQDEKINNL-LLEIKEKDCLIERINQQLLE 725 Query: 518 EIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKV-SDSNKEIVRLTEELHHLSQKVAELEE 576 ID +K + KL ++ + +++ S ++ +L +E +++ +E+ Sbjct: 726 NIDLNSKYQQLLLEFENFKLNSSKEKENQLNELQSKQDERFNQLNDEKLEKEKQLQSIED 785 Query: 577 EKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQK 636 E + + +S I+ + +IE+ L E + L +S+ + ++L LQQ+ Sbjct: 786 EFNQYKQQQLSSNSN--IDQQLQSTIIELSELKEQK----ELNDSKLIEKEKQLQQLQQE 839 Query: 637 YDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTI 696 +D++ +K Q Q + + ++K L+++ D L+ + + IEN +L+++ L Sbjct: 840 FDQLNEKNQKDHQDQLELLEKQLKQ--LQQEYDQLNETNQS----IEN-QLNQQNLIN-- 890 Query: 697 KDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAK 756 K+ N+KE + KLQN + + ++ ++ +++ S + +N + + IQ Q D Sbjct: 891 KENLNEKEQELLKLQNQLNQQIEKIQFDQQEFSKQNSINIELVNEKNEKLIQLQQDYDQL 950 Query: 757 IQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEY 816 Q+ E E++L + ++++ ++ + + ++ S + K QL KQ++ Sbjct: 951 KQQNRSNDEKDENDLIEKENQLKSIQNELNQLIEKNES-DHKEQQL------KQQSIEND 1003 Query: 817 TIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHY 876 I+++ + +L ++ R ++Q ++ ++++L NQ L+E+NQ Q Sbjct: 1004 LIEKENQIQQLQSQLNEQR--QQQSNQLSEKDQQL---NQ-LIEKNQ--------FDQKE 1049 Query: 877 NALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDL-EIEFNTQ 935 L +++ DL E E+ Q++ L+S L + + +K +++ L E + Q Sbjct: 1050 QQLKQQSIENDLFEKEN-----QIQQLQSQLNEQRQQQSNQLSEKDQQLNQLIEKNESDQ 1104 Query: 936 IESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQK 995 E ++ + + N+ EK + + QL+ QL E + L V N LEL +K +++ Sbjct: 1105 KEQQLKQQSIENDLIEKENQ-IQQLQLQLNEQRQ----LQSEVSIDNDKILEL-EKQLKQ 1158 Query: 996 QQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTT 1055 Q+ ++ + +L + D+ + NQ N+ ++ + D + +L Sbjct: 1159 CQSDLLKLNDEKQQQDKQLQDKQIEFDQLQLTFNQFKNDKDSQFIQLQDDQKQQLQSIQQ 1218 Query: 1056 KLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEG---- 1111 L +++E Q KQL + + + +Q +E++ Q+ E E + + N+ + Sbjct: 1219 DLNQLKQENQEKEKQLSEKDEKLQSIQFENQEKEKQLSEKDEKLQSIQQNLNQLNDENQE 1278 Query: 1112 --MIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEE--EEFIQERSVLQEQSAKLNTE 1167 S E + +++ L ++E + Q+ + L + K N + Sbjct: 1279 KVKQFSEKDEKLQSIQQDLNQLKQENQEKEKQLSEKDEKLQSIQQDLNQLNDDQIKKNEK 1338 Query: 1168 LQECYTKIIQLET-LNTELTGHDVVNQEQINQLKSKLEQLNTEND-NLLSTVAELRSSIS 1225 L+E ++++L+ N + + +E++++ +++L+QL EN+ N L+ + I Sbjct: 1339 LKEKEEQLLKLQQDFNDQQSQQLKQLEEKLSEKENQLQQLKQENEINQLNQQQQSNEIIQ 1398 Query: 1226 SAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNK 1285 DQ L KQ +++ + + E E +Q + K +Q +D + S +E + Sbjct: 1399 QLKDQ-------LLKQQQQEQQENNNEKEIERLIQ-EIEQLKQQQEIDQSELSNKEIKIQ 1450 Query: 1286 IVTMEQVTSLQNKLQDKEEHLRNLQEK 1312 T ++ L + + HL+ LQ++ Sbjct: 1451 -TTQQEFDQLSHNRSKDQLHLQQLQQE 1476 Score = 116 bits (278), Expect = 7e-24 Identities = 205/1011 (20%), Positives = 446/1011 (44%), Gaps = 86/1011 (8%) Query: 147 LSNTIKEKDNALSVLQVKMKIMETT-ILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXX 205 L+ + EKD + L + + + I +L +I EKD +IE N+ Sbjct: 676 LNKQLSEKDKEIEKLSNQQEQQQDEKINNLLLEIKEKDCLIERINQQLLENIDLNSKYQQ 735 Query: 206 XXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIE-SKDVRISSLE-EANKLLE-- 261 E+ K +K +EN + +DE+ L D + K+ ++ S+E E N+ + Sbjct: 736 LLLEF-ENFKLNSSKEKENQLNELQSKQDERFNQLNDEKLEKEKQLQSIEDEFNQYKQQQ 794 Query: 262 -AARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIAN 320 ++ I + EL + KQ ++ +E ++ EK + + Sbjct: 795 LSSNSNIDQQLQSTIIELSELKEQKELNDSKLIEKEKQ-LQQLQQEFDQLNEKNQKDHQD 853 Query: 321 MTELTKK-IELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTA 379 EL +K ++ L+ Q+ +TN+ +EN+L +K + ++K L+ ++ N Sbjct: 854 QLELLEKQLKQLQQEYDQLNETNQSIENQLNQQNLINK--ENLNEKEQELLKLQNQLNQQ 911 Query: 380 SKMKSPWSQLSSETLNQDTDKKIN-KNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXX 438 + K + Q N + +N KNE KL + Q ++ L + EKD Sbjct: 912 IE-KIQFDQQEFSKQNSINIELVNEKNE--KLIQLQQDYDQ-LKQQNRSNDEKDENDLIE 967 Query: 439 XXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNV 498 K+ + +Q E Q +E N D E Q+ ++ +L + K+ + Sbjct: 968 ------KENQLKSIQNELNQLIE--------KNESDHKEQQLKQQSIENDLIE--KENQI 1011 Query: 499 KDLIEKL-KSAEEQITQLNDEIDAANKNMIKVKSNHK-LKLKQMQKTIDNFSKVSDSNKE 556 + L +L + ++Q QL+++ N+ + K + + K +LKQ D F K + + Sbjct: 1012 QQLQSQLNEQRQQQSNQLSEKDQQLNQLIEKNQFDQKEQQLKQQSIENDLFEKENQIQQL 1071 Query: 557 IVRLTEELHHLSQKVAELEEEKGNL-QLHLVDYDSGRMIESDVYKKMIEMENLAETRLKA 615 +L E+ S +++E +++ L + + D ++ + + +IE EN +++ Sbjct: 1072 QSQLNEQRQQQSNQLSEKDQQLNQLIEKNESDQKEQQLKQQSIENDLIEKEN----QIQQ 1127 Query: 616 ISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASK 675 + L +++ L E+ I K E+E +L Q QSD + + ++Q+ Sbjct: 1128 LQLQLNEQRQLQSEVSIDNDKILELEKQL---KQCQSDLLKLNDEKQQQDKQLQDKQIEF 1184 Query: 676 KELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISEL 735 +L L K DK+ + L++D++ + +Q + + + EK +EK E Sbjct: 1185 DQLQLTFNQFKNDKDSQF---IQLQDDQKQQLQSIQQDLNQLKQENQEKEKQLSEK-DEK 1240 Query: 736 LAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSL 795 L I E Q K + ++ E+D +++I+ L++ + + +++ S+ Sbjct: 1241 LQSIQFENQEK-------EKQLSEKDEKLQSIQQNLNQLNDENQEKVKQFSEKDEKLQSI 1293 Query: 796 ERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKN 855 ++ +QL QEK+K SE +DE + ++ D +++ + Q+ +N++L++K Sbjct: 1294 QQDLNQLKQENQEKEKQLSE----KDEKLQ--SIQQDLNQLNDDQI----KKNEKLKEKE 1343 Query: 856 QILLEENQNLQISLS-DMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEH 914 + LL+ Q+ S ++Q L EK N+ + E+ QL + + + I Sbjct: 1344 EQLLKLQQDFNDQQSQQLKQLEEKLSEKENQLQQLKQENE--INQLNQQQQSNEIIQQLK 1401 Query: 915 QTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENL 974 L+ Q+++E ++ E +IE I++ + L ++ E + ++ E ++Q + + L Sbjct: 1402 DQLLKQQQQEQQENNNE--KEIERLIQEIEQLKQQQEIDQSELSNKEIKIQTTQQEFDQL 1459 Query: 975 NMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQ--KI 1032 + N ++++L+ + + + + + D Q+ I++ L Q ++ ++ NQ ++ Sbjct: 1460 SHN-RSKDQLHLQQLQQELDQLKQSFDDQDHQFKKVIDERYNLQLQLEQSTLSNNQLDQL 1518 Query: 1033 NNAQVSYMSMVSDYESK-LAQFTTKLENMEEEMQRVSKQLLDSKQHN---EELQI----- 1083 ++ + + S+ + K + + + N++ +Q K L+ + ++ E +I Sbjct: 1519 LKEKLKPLELDSNEKQKTIDDLLSNISNLQISLQN-DKDLISERNNSIKTLESRITQQLS 1577 Query: 1084 LVREQDDQIKELKETKLTFEM-----NIPKTEGMIISSTIEPMSDDANNVD 1129 L+ E+D+ IK+L++ K + + P + ++SST P N ++ Sbjct: 1578 LLDEKDNLIKDLQQQKQQQQQPPTASSSPSSSPSLLSSTPTPKPQRPNQIE 1628 Score = 87.0 bits (206), Expect = 4e-15 Identities = 149/760 (19%), Positives = 334/760 (43%), Gaps = 75/760 (9%) Query: 147 LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINE-KDQIIEAKNKATTXXXXXXXXXXX 205 L+ I++ ++ Q+K + +E +++ + +I + + Q+ E + + + Sbjct: 979 LNQLIEKNESDHKEQQLKQQSIENDLIEKENQIQQLQSQLNEQRQQQSNQLSEKDQQLNQ 1038 Query: 206 XXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEA-AR 264 D K+Q K Q ++E + EK+ ++ ++S+ + +++N+L E + Sbjct: 1039 LIEKNQFDQKEQQLKQQ----SIENDLF-EKENQIQQLQSQ-LNEQRQQQSNQLSEKDQQ 1092 Query: 265 FEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTEL 324 +E ++ Q+ +Q Q ++ E+ +++ + S++ + EL Sbjct: 1093 LNQLIEKNESDQKEQQLKQQSIENDLIEKENQIQQLQLQLNEQRQLQSEVSIDNDKILEL 1152 Query: 325 TKKIELLEH----LNCQIRQTNKELENKLATMGTESKAVSS-PSKKGSPLISRKSG-RNT 378 K+++ + LN + +Q +K+L++K + + K S I + + Sbjct: 1153 EKQLKQCQSDLLKLNDEKQQQDKQLQDKQIEFDQLQLTFNQFKNDKDSQFIQLQDDQKQQ 1212 Query: 379 ASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXX 438 ++ +QL E NQ+ +K++++ + KL QS+ + +KE +SEKD Sbjct: 1213 LQSIQQDLNQLKQE--NQEKEKQLSEKD-EKL----QSIQFENQEKEKQLSEKDEKLQSI 1265 Query: 439 XXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNV 498 + QL E+Q+ ++ E + I + QLKQE ++ K ++ Sbjct: 1266 QQN-------LNQLNDENQEKVK-----QFSEKDEKLQSIQQDLNQLKQENQEKEKQLSE 1313 Query: 499 KDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQ--KTIDNFSKVSDSNKE 556 KD EKL+S ++ + QLND+ ++K N KLK K+ Q K +F+ +++ Sbjct: 1314 KD--EKLQSIQQDLNQLNDD---------QIKKNEKLKEKEEQLLKLQQDFN--DQQSQQ 1360 Query: 557 IVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIES--DVYKKMIEMENLAETRLK 614 + +L E+L ++ +L++E QL+ S +I+ D K + E K Sbjct: 1361 LKQLEEKLSEKENQLQQLKQENEINQLNQ-QQQSNEIIQQLKDQLLKQQQQEQQENNNEK 1419 Query: 615 AISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSAS 674 I L +QE+ L+Q+ + D S+L + EIK +++ D LS + Sbjct: 1420 EIERL-------IQEIEQLKQQQE------IDQSELSN----KEIKIQTTQQEFDQLSHN 1462 Query: 675 KKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISE 734 + + L ++ L+ + +QL + D ++ + ++++ N +Q ++ + + + E Sbjct: 1463 RSKDQLHLQQLQQELDQLKQSFDDQDHQFKKVIDERYN-LQLQLEQSTLSNNQLDQLLKE 1521 Query: 735 LLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYS 794 L + + K +T + + I + ++N + +S+ + I LE I ++ S Sbjct: 1522 KLKPLELDSNEKQKTIDDLLSNISNLQISLQNDKDLISERNNSIKTLESRIT----QQLS 1577 Query: 795 LERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHD--RVVEKQLLEIEHENKELQ 852 L + D L LQ++++ + + ++L + +EI+ E+ Sbjct: 1578 LLDEKDNLIKDLQQQKQQQQQPPTASSSPSSSPSLLSSTPTPKPQRPNQIEIDRLVNEIV 1637 Query: 853 KKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESE 892 +NQ L+ +N+ L + N+++ + + D +S+ Sbjct: 1638 NRNQDLIRKNKTKFYKLENGDYIVNSIIYRLSLDDDNDSD 1677 Score = 77.8 bits (183), Expect = 2e-12 Identities = 153/736 (20%), Positives = 284/736 (38%), Gaps = 43/736 (5%) Query: 859 LEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLI 918 L N N+ SLS K N L++S S + Q Q + + NL ++ Sbjct: 255 LNNNNNISPSLSSSSSSLLNTPNKRNSIQLSKSTSFEQQNQ-QQQQQNLLSPNSYRNSIS 313 Query: 919 VQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNV 978 K E + +++ S I + N+ T E E N N + + Sbjct: 314 FSKSPSFEGSQSTGSSRSISPISSPIKNSTTGNSNLSKSTSFEK--IEASNTTNNNTIII 371 Query: 979 EELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKD-EEIIALN--QKINNA 1035 E +++ ++++K ++ ++ + I E+ K+ + K + E+I+ ++ +K+ N Sbjct: 372 AEESRVIEKIVEKIIEVEKI----VEVEKIVEVEKIVEVEKIVEVEKIVKVDDIEKLTNL 427 Query: 1036 QVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKEL 1095 Q Y+ K + KL N+E E+Q S QL+D +Q E ++I L Sbjct: 428 QDQLTEQQQQYQEK----SLKLVNLELELQEKSNQLVDKSNQLSTMQATNSELMEKIGGL 483 Query: 1096 KETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERS 1155 K + II++ + N+ + I++ S Sbjct: 484 MNDLTDIPTQDIKEKDEIIANL---KIESEKNLKCFQDDFNALQSRYSLT-----IEQTS 535 Query: 1156 VLQEQSAKLNTELQECYTKIIQL-ETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLL 1214 LQ++ +L ELQE K I+ + N L + V + N+ +S QL + D Sbjct: 536 QLQDRIKQLINELQERDDKFIEFTNSSNQSLADNQRVIDQLTNEKQSITLQLQDQQDIKE 595 Query: 1215 STVAELRSSISSAVDQRGFEIAELW-KQHLAQREADFQKT-----EHELRVQLSAFESKY 1268 + + S +D I E K + Q+E + Q+T H L QL + Y Sbjct: 596 KEFQFEKQQLLSQIDSITTNIQEYQDKFNNLQQEFNTQQTLNQQETHRLTQQLYQINTDY 655 Query: 1269 EQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKE-EHLRNLQEKYAD-VINQIEILRSE 1326 + Q+ Q E T+ + + Q +DKE E L N QE+ D IN + +L + Sbjct: 656 NE----KQTQLQSEIKDNQTINEQLNKQLSEKDKEIEKLSNQQEQQQDEKINNL-LLEIK 710 Query: 1327 IEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILN-INEENAQLKKSSXXXX 1385 +D + L E +++K + N +NE ++ + Sbjct: 711 EKDCLIERINQQLLENIDLNSKYQQLLLEFENFKLNSSKEKENQLNELQSKQDERFNQLN 770 Query: 1386 XXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYE 1445 ++ E + + Q +S I Q+ I L++ ++ E +L+E E Sbjct: 771 DEKLEKEKQLQSIEDEFNQYKQQQLSSNSNIDQQLQSTIIELSELKEQKELNDSKLIEKE 830 Query: 1446 KRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQV 1505 K+++ L E + +L K H++ Q + + + E N I LN+Q Sbjct: 831 KQLQQLQQEFD-QLNEKNQKDHQDQLELLEKQLKQLQQEYDQLNETNQSIEN--QLNQQN 887 Query: 1506 AELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRAS--SSKIQKHVSFASD 1563 + L E+ + ++Q L NQ+IE + + + + QN + + K +K + D Sbjct: 888 LINKENLNEKEQELLKLQNQL-NQQIEKIQFDQQEFSKQNSINIELVNEKNEKLIQLQQD 946 Query: 1564 TKQGRDEQLDNTMNKE 1579 Q + + N E Sbjct: 947 YDQLKQQNRSNDEKDE 962 Score = 41.1 bits (92), Expect = 0.25 Identities = 76/399 (19%), Positives = 160/399 (40%), Gaps = 21/399 (5%) Query: 143 DVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXX 202 D+ L +EK+ LS K++ ++ + +++++EKD+ +++ + Sbjct: 1219 DLNQLKQENQEKEKQLSEKDEKLQSIQFENQEKEKQLSEKDEKLQSIQQ--NLNQLNDEN 1276 Query: 203 XXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEA 262 +D K Q + N + K E Q K + KD ++ S+++ L Sbjct: 1277 QEKVKQFSEKDEKLQSIQQDLN------QLKQENQEKEKQLSEKDEKLQSIQQDLNQLND 1330 Query: 263 ARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEE-KGSLEIANM 321 + + ++ KL ++ EQ KQ E E++ ++++ K EI + Sbjct: 1331 DQIK---KNEKLKEKEEQLLKLQQDFNDQQSQQLKQLEEKLSEKENQLQQLKQENEINQL 1387 Query: 322 TELTKKIELLEHLNCQ-IRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTAS 380 + + E+++ L Q ++Q +E + E K I + N Sbjct: 1388 NQQQQSNEIIQQLKDQLLKQQQQEQQENNNEKEIERLIQEIEQLKQQQEIDQSELSNKEI 1447 Query: 381 KMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXX 440 K+++ + + N+ D+ + +L+ + QS + + VI E+ Sbjct: 1448 KIQTTQQEFDQLSHNRSKDQLHLQQLQQELDQLKQSFDDQDHQFKKVIDERYNLQLQLEQ 1507 Query: 441 XXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKD 500 + L QL E + +E S T + ++ I+ +Q L+ ND KD+ + + Sbjct: 1508 STLSNNQL-DQLLKEKLKPLELDSNEKQKTIDDLLSNISNLQISLQ---ND--KDL-ISE 1560 Query: 501 LIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQ 539 +K+ E +ITQ +D + N+IK K + +Q Sbjct: 1561 RNNSIKTLESRITQQLSLLDEKD-NLIKDLQQQKQQQQQ 1598 >UniRef50_A0DDW1 Cluster: Chromosome undetermined scaffold_47, whole genome shotgun sequence; n=1; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_47, whole genome shotgun sequence - Paramecium tetraurelia Length = 1279 Score = 147 bits (357), Expect = 2e-33 Identities = 229/1183 (19%), Positives = 509/1183 (43%), Gaps = 101/1183 (8%) Query: 404 KNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGP 463 K E L I+SL++ L D Y+I + + + L ++ + Sbjct: 150 KIENISLSNTIKSLSQQLSDARYIIQRLYSQVDLNQQQDTQDNNSTQENNLVFYEY-QNF 208 Query: 464 SLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLI-EKLKSAEEQITQ--LNDEID 520 L + + + +++E+ ++ ++ +N K I E L S+ QI + +E+ Sbjct: 209 ILRQLNELEQQTLQSLELKEEKMLKIMKKLNKINRKQQIDEDLLSSARQIDSKTIINELK 268 Query: 521 AANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGN 580 +N+++ N +++LKQ QK K++ + + + E Q + LE+EK Sbjct: 269 QDKQNLLQKVKNLEIQLKQEQKKPSYEQKLNQAQQIEEQFNEFKKKHQQIIYNLEQEKST 328 Query: 581 L--QLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYD 638 + L+ ++ + I+ + ++I + + E R + I L +Q + + QQ Sbjct: 329 SLEKEQLIKKEAQQKIKK-LESQLIALMDELEGRDQIIESL-NQTINQNKNQSQKQQDVQ 386 Query: 639 EVEDKLADISQLQSD-QVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIK 697 ++ +KL + Q+Q D ++ + ++ L SK E ++ ++ D L G Sbjct: 387 QLINKLKENEQIQQDLNQQIQLMKKNNNTILNELENSKVE----VQKIRKDYSTLQGQFD 442 Query: 698 DLENDKEDIMNKLQNYIQENMDLTDKLE---KMSAEKISELLAKINHEEQSKIQTQFG-I 753 + + +++ K+Q Q+ D L ++ EK+SE LA IN ++ +K+ + + Sbjct: 443 YTKQENTELIKKIQYVNQQKQQSIDSLNDQWQIHNEKLSEQLA-INEDKYAKLSINYNQL 501 Query: 754 DAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAY 813 + Q+ + ++ E EL + E+ + + +++ A Q Y K Sbjct: 502 SKQKQDLETQLKLKEKELESKLEELTEFEQLQLRVNKQNQTIQNLAQQNQQYEATLVKNI 561 Query: 814 SEYTIQEDELVNRLAVLMD------HDRVVEKQLLEIEHENKELQKKNQILLEENQNLQI 867 E E ++ + + L D + +++ ++++ + E +L K+N LL E LQ Sbjct: 562 DEKKQFEKQIQDLMEKLKDLSQDNLNQQLLSDKIVKYQQEIDKLNKQNSRLLNEKNELQE 621 Query: 868 SLSDMQQHYNALVEKANRTD----LAESE-------STKYQTQLRDLESNLKRITHEHQT 916 S+ + + + L++ + + LA E TKYQ + DL + +T +++ Sbjct: 622 SIKNEKDKSDLLIQNLEKLEDQLALANQEIEEQTQKITKYQKENLDLLKQMDELTAKNKK 681 Query: 917 LIVQKKKEIEDLEIEFNTQI---ESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIEN 973 L+ ++ +E E+ ++ E+ + + + N E+ IE + E + Q+ + I N Sbjct: 682 LLKEQNEEWEEQNNNLLQKLALSENNLLNLQQKNTNQERIIEKLQVFEIENQKKDDYILN 741 Query: 974 LNMNVEELNKMN-LELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKI 1032 L +++ ++N + + Q Q D ++ +N L + E L K+ Sbjct: 742 LKQQLDDQGQINQFNQNTQEIVDLQNQLLDVNKEKEQLLNDNIQLQNEFGNEKQILENKV 801 Query: 1033 NNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQI 1092 ++ + YE++L Q+ T +++++ +QL++ + +E QI + Q+ Sbjct: 802 DDQS----KKLEQYENELQQYKTNQLQFNDKLKQAQRQLVELQSELQEEQIKSLQLQSQL 857 Query: 1093 KELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQ 1152 + + E K + + N + I S I P VQ++++ Sbjct: 858 QSISENKSSLQQNQDLLD--IFESQISPRQQ-----ATVQQMTETISYTESVQQQDQL-- 908 Query: 1153 ERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDN 1212 +L++Q +L +QE +I Q+ E+ V E++N ++ + QLN EN Sbjct: 909 --HLLKQQIQQLQEIIQEKDLEINQVIQQKNEMESSLDVAIEKMNNQENLILQLNQENGK 966 Query: 1213 LLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLL 1272 L + E +S I+ ++ E+ Q L + D Q+ +L +E+K ++ Sbjct: 967 L---IEEQKSEINH--QKQKISSQEMVIQSLQSQIEDLQQ-------ELQGYENKQKEQE 1014 Query: 1273 DSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKV 1332 D++Q KI+ Q L+ + +K++ +++L+E+ +N+I +++++ V Sbjct: 1015 DNIQ-------KKILEQNQEQQLKKLIAEKDQEIQSLREQ----LNKIHEQFDQLQNKSV 1063 Query: 1333 AFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXX 1392 D+ E ++ ++++++ L EN LK+ Sbjct: 1064 LSNRSKRSFQVAKFDQFRDI-NEEENNEELEDEDDLKF--ENMILKEQ-------INKKE 1113 Query: 1393 XRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLT 1452 + E ++ Q D+E Q+T + L +N E + Q++ + +K +E L Sbjct: 1114 DLIKQQEQQIKSFNEQ----DNEKSQQTEKEKQLLQNQN---ELLLQEIDKMQKEMEKLK 1166 Query: 1453 YEKESELAILRLKMHEN--ANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNK 1510 E+ L L+M+++ +N + Q + + ++ + + + N + ++ N+ ELN Sbjct: 1167 EEQRRMLEQFELQMNKSVISNRSKRSQNQIQYDQFQDLPDDNSQGSQDEDENE---ELNL 1223 Query: 1511 ALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSK 1553 + ++ KT++ Q ++N + I L +E +LQ + +K Sbjct: 1224 FVLQK--KTSDQQKQIQNLQETIQKLKEENNSLQEEINVLKNK 1264 Score = 133 bits (322), Expect = 3e-29 Identities = 202/1014 (19%), Positives = 443/1014 (43%), Gaps = 76/1014 (7%) Query: 372 RKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEK 431 ++ +N K+K+ QL E ++K+N+ + ++E K Y + ++ Sbjct: 268 KQDKQNLLQKVKNLEIQLKQEQKKPSYEQKLNQAQ--QIEEQFNEFKKKHQQIIYNLEQE 325 Query: 432 DTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAK-VQEQLKQELN 490 + K+ LI + + + +E LI + E ++I + + + + Q N Sbjct: 326 KSTSLE-------KEQLIKKEAQQKIKKLES-QLIALMDELEGRDQIIESLNQTINQNKN 377 Query: 491 DEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKN---MIKVKSNHKLKLKQMQKTIDNF 547 K +V+ LI KLK E+ LN +I KN ++ N K+++++++K Sbjct: 378 QSQKQQDVQQLINKLKENEQIQQDLNQQIQLMKKNNNTILNELENSKVEVQKIRKDYSTL 437 Query: 548 SKVSDSNK-EIVRLTEELHHLS-QKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKM-IE 604 D K E L +++ +++ QK ++ Q+H I D Y K+ I Sbjct: 438 QGQFDYTKQENTELIKKIQYVNQQKQQSIDSLNDQWQIHNEKLSEQLAINEDKYAKLSIN 497 Query: 605 MENLA------ETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSE 658 L+ ET+LK K + + E LQ + ++ + +++Q + Sbjct: 498 YNQLSKQKQDLETQLKLKEKELESKLEELTEFEQLQLRVNKQNQTIQNLAQQNQQYEATL 557 Query: 659 IKSV----HLEEQIDALSASKKELAL--VIENLKLDKEQLYGTIKDLENDKEDIM----N 708 +K++ E+QI L K+L+ + + L DK Y D N + + N Sbjct: 558 VKNIDEKKQFEKQIQDLMEKLKDLSQDNLNQQLLSDKIVKYQQEIDKLNKQNSRLLNEKN 617 Query: 709 KLQNYIQENMDLTDKLEKMSAEKISELLAKINH--EEQSKIQTQF---GIDAKIQERDLY 763 +LQ I+ D +D L + + EK+ + LA N EEQ++ T++ +D Q +L Sbjct: 618 ELQESIKNEKDKSDLLIQ-NLEKLEDQLALANQEIEEQTQKITKYQKENLDLLKQMDELT 676 Query: 764 IEN---IESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQE 820 +N ++ + +++ + L + +A+ E+ +L++K +++ Q E ++ Sbjct: 677 AKNKKLLKEQNEEWEEQNNNLLQKLALSENNLLNLQQKNTNQERIIEKLQVFEIENQKKD 736 Query: 821 DELVNRLAVLMDHDRVVE-----KQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQH 875 D ++N L D ++ + +++++++++ ++ K+ + LL +N LQ + +Q Sbjct: 737 DYILNLKQQLDDQGQINQFNQNTQEIVDLQNQLLDVNKEKEQLLNDNIQLQNEFGNEKQI 796 Query: 876 Y-NALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLE-IEFN 933 N + +++ + + E+E +Y+T LK+ + Q + +Q + + E ++ ++ Sbjct: 797 LENKVDDQSKKLEQYENELQQYKTNQLQFNDKLKQA--QRQLVELQSELQEEQIKSLQLQ 854 Query: 934 TQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMN-LELIDKH 992 +Q++S +K L + + + +Q+ + Q + E + + + L L+ + Sbjct: 855 SQLQSISENKSSLQQNQDLLDIFESQISPRQQATVQQMTETISYTESVQQQDQLHLLKQQ 914 Query: 993 VQKQQ--TQSPDY-TEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESK 1049 +Q+ Q Q D Q I + N++ + L E++ I ++ + +S+ Sbjct: 915 IQQLQEIIQEKDLEINQVIQQKNEMESSLDVAIEKMNNQENLILQLNQENGKLIEEQKSE 974 Query: 1050 LAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQI--KELKETKLTFEMNIP 1107 + K+ + E +Q + Q+ D +Q + + +EQ+D I K L++ + + Sbjct: 975 INHQKQKISSQEMVIQSLQSQIEDLQQELQGYENKQKEQEDNIQKKILEQNQEQQLKKLI 1034 Query: 1108 KTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQ-SAKLNT 1166 + I S E ++ D + + +F Q R + +E+ + +L Sbjct: 1035 AEKDQEIQSLREQLNKIHEQFDQLQNKSVLSNRSKRSFQVAKFDQFRDINEEENNEELED 1094 Query: 1167 ELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLN-----TEND-NLLSTVAEL 1220 E + +I E +N + D++ Q++ Q+KS EQ N TE + LL EL Sbjct: 1095 EDDLKFENMILKEQINKK---EDLIKQQE-QQIKSFNEQDNEKSQQTEKEKQLLQNQNEL 1150 Query: 1221 RSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQ 1280 + + ++ E ++ L Q E K+ R + S + +Y+Q D ++Q Sbjct: 1151 LLQEIDKMQKEMEKLKEEQRRMLEQFELQMNKSVISNRSKRSQNQIQYDQFQDLPDDNSQ 1210 Query: 1281 --------EETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSE 1326 EE N V ++ + Q ++Q+ +E ++ L+E+ + +I +L+++ Sbjct: 1211 GSQDEDENEELNLFVLQKKTSDQQKQIQNLQETIQKLKEENNSLQEEINVLKNK 1264 Score = 128 bits (308), Expect = 2e-27 Identities = 217/1109 (19%), Positives = 493/1109 (44%), Gaps = 127/1109 (11%) Query: 475 VNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHK 534 +N+I + Q Q+ ++L + ++ K +I +LK ++ + Q ++ K K K +++ Sbjct: 238 LNKINRKQ-QIDEDLLSSARQIDSKTIINELKQDKQNLLQKVKNLEIQLKQEQK-KPSYE 295 Query: 535 LKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMI 594 KL Q Q+ + F++ +++I+ E+ S + +L +++ ++ + + Sbjct: 296 QKLNQAQQIEEQFNEFKKKHQQIIYNLEQEKSTSLEKEQLIKKEAQQKI--------KKL 347 Query: 595 ESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQ 654 ES + M E+E + +++++ +Q + Q+ QQ ++ +KL + Q+Q D Sbjct: 348 ESQLIALMDELEGRDQI-IESLNQTINQNKNQSQK----QQDVQQLINKLKENEQIQQD- 401 Query: 655 VCSEIKSVHLEEQ--IDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQN 712 + +I+ + ++ L SK E ++ ++ D L G + + +++ K+Q Sbjct: 402 LNQQIQLMKKNNNTILNELENSKVE----VQKIRKDYSTLQGQFDYTKQENTELIKKIQY 457 Query: 713 YIQENMDLTDKLE---KMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIES 769 Q+ D L ++ EK+SE LA IN ++ +K+ + +K Q++DL E+ Sbjct: 458 VNQQKQQSIDSLNDQWQIHNEKLSEQLA-INEDKYAKLSINYNQLSK-QKQDL-----ET 510 Query: 770 ELS-KYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLA 828 +L K K +LEE + E + + ++ + + Q+ Q+ E LV + Sbjct: 511 QLKLKEKELESKLEE-LTEFEQLQLRVNKQNQTIQNLAQQNQQ-------YEATLVKNI- 561 Query: 829 VLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDL 888 D + EKQ+ ++L +K + L ++N N Q+ LSD Y ++K N+ Sbjct: 562 ---DEKKQFEKQI-------QDLMEKLKDLSQDNLNQQL-LSDKIVKYQQEIDKLNK--- 607 Query: 889 AESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNE 948 ++++ + +L+ ++K + L++Q +++ED N +IE + +K+ Sbjct: 608 ---QNSRLLNEKNELQESIKN-EKDKSDLLIQNLEKLEDQLALANQEIEE--QTQKIT-- 659 Query: 949 KYEK-NIEYVTQLEAQLQEYKNNIENLNMNVEELNK---MNLELIDKHVQKQQTQSPDYT 1004 KY+K N++ + Q++ + K ++ N EE N L L + ++ Q ++ + Sbjct: 660 KYQKENLDLLKQMDELTAKNKKLLKEQNEEWEEQNNNLLQKLALSENNLLNLQQKNTNQ- 718 Query: 1005 EQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEM 1064 E+ I ++ ++KD+ I+ L Q++++ ++ + ++ +L ++ +E Sbjct: 719 ERIIEKLQVFEIENQKKDDYILNLKQQLDDQ--GQINQFNQNTQEIVDLQNQLLDVNKEK 776 Query: 1065 QRVSKQLLD-SKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSD 1123 +++ + + E QIL + DDQ K+L++ + E+ KT + + ++ Sbjct: 777 EQLLNDNIQLQNEFGNEKQILENKVDDQSKKLEQYEN--ELQQYKTNQLQFNDKLKQAQR 834 Query: 1124 DANNVDXXXXXXXXXXXXLKVQEEEEFIQE-RSVLQEQSAKLN---TELQECYTKIIQLE 1179 V+ L++Q + + I E +S LQ+ L+ +++ +Q Sbjct: 835 QL--VELQSELQEEQIKSLQLQSQLQSISENKSSLQQNQDLLDIFESQISPRQQATVQQM 892 Query: 1180 TLNTELTGHDVVNQEQINQLKSKLEQLNT---ENDNLLSTVAELRSSISSAVDQRGFEIA 1236 T T V Q+Q++ LK +++QL E D ++ V + ++ + S++D +A Sbjct: 893 TETISYT-ESVQQQDQLHLLKQQIQQLQEIIQEKDLEINQVIQQKNEMESSLD-----VA 946 Query: 1237 ELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVT-SL 1295 + + L +QL+ K L++ +S + KI + E V SL Sbjct: 947 -----------IEKMNNQENLILQLNQENGK---LIEEQKSEINHQKQKISSQEMVIQSL 992 Query: 1296 QNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTE 1355 Q++++D ++ L+ + K + + I+ E ++++ L Sbjct: 993 QSQIEDLQQELQGYENKQKEQEDNIQKKILE-QNQEQQLKKLIAEKDQEIQSLREQLNKI 1051 Query: 1356 NQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSE 1415 ++ + Q+Q +S+L+ +S +N+ E EL + +LK Sbjct: 1052 HEQFDQLQNKSVLS--------NRSKRSFQVAKFDQFRDINEEENNE-ELEDEDDLKFEN 1102 Query: 1416 IYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYET 1475 + K + ++ D + QQ+ + ++ + + + E E +L+ + + Sbjct: 1103 MILKEQ-----INKKEDLIKQQEQQIKSFNEQDNEKSQQTEKEKQLLQNQNELLLQEIDK 1157 Query: 1476 MQKESEI---ERVKLIEELNVKITESVSLNKQVAELNKALEEEVA-----KTNEMQTALE 1527 MQKE E E+ +++E+ +++ +SV N+ N+ ++ + Q E Sbjct: 1158 MQKEMEKLKEEQRRMLEQFELQMNKSVISNRSKRSQNQIQYDQFQDLPDDNSQGSQDEDE 1217 Query: 1528 NQEIEIVTLNDEITNLQNMVRASSSKIQK 1556 N+E+ + L + ++ Q ++ IQK Sbjct: 1218 NEELNLFVLQKKTSDQQKQIQNLQETIQK 1246 Score = 118 bits (283), Expect = 2e-24 Identities = 231/1119 (20%), Positives = 506/1119 (45%), Gaps = 143/1119 (12%) Query: 91 SESLANTLKQ-KEILMEKIK----QYKELSKRSS--TTIVRXXXXXXXXXXXXXXXQ--L 141 S+++ N LKQ K+ L++K+K Q K+ K+ S + + Q + Sbjct: 260 SKTIINELKQDKQNLLQKVKNLEIQLKQEQKKPSYEQKLNQAQQIEEQFNEFKKKHQQII 319 Query: 142 GDVTHLSNTIKEKDNALSV-LQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXX 200 ++ +T EK+ + Q K+K +E+ ++ L +++ +DQIIE+ N+ T Sbjct: 320 YNLEQEKSTSLEKEQLIKKEAQQKIKKLESQLIALMDELEGRDQIIESLNQ--TINQNKN 377 Query: 201 XXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLL 260 + ++ ++Q++ K +L ++E+ V + + + L Sbjct: 378 QSQKQQDVQQLINKLKENEQIQQDLNQQIQLMKKNNNTILNELENSKVEVQKIRKDYSTL 437 Query: 261 EAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIAN 320 + E+++L ++++ + E E+ E+K + N Sbjct: 438 QGQFDYTKQENTELIKKIQYVNQQKQQSIDSLNDQWQIHNEKLSEQLAINEDKYAKLSIN 497 Query: 321 MTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTAS 380 +L+K+ + LE Q++ KELE+KL + TE + + K + I + +N Sbjct: 498 YNQLSKQKQDLE---TQLKLKEKELESKLEEL-TEFEQLQLRVNKQNQTIQNLAQQN--- 550 Query: 381 KMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXX 440 Q TL ++ D+K + E IQ DL++K +S+ + Sbjct: 551 -------QQYEATLVKNIDEK------KQFEKQIQ----DLMEKLKDLSQDNL------- 586 Query: 441 XXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKD 500 L++ +++QQ ++ + N+ +NE ++QE +K E KD + Sbjct: 587 ----NQQLLSDKIVKYQQEIDKLN----KQNSRLLNEKNELQESIKNE-----KDKS-DL 632 Query: 501 LIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQK-TIDNFSKVSDSNKEIVR 559 LI+ L+ E+Q+ N EI+ + + K + + LKQM + T N + + N+E Sbjct: 633 LIQNLEKLEDQLALANQEIEEQTQKITKYQKENLDLLKQMDELTAKNKKLLKEQNEE--- 689 Query: 560 LTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLL 619 E+ ++L QK+A E NLQ + + R+IE ++ E+EN + + I L Sbjct: 690 WEEQNNNLLQKLALSENNLLNLQQKNTNQE--RIIEK---LQVFEIEN--QKKDDYILNL 742 Query: 620 ESQKFD--LVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKE 677 + Q D + + + Q+ +++++L D+++ + +Q+ ++ ++ L+ + ++K+ Sbjct: 743 KQQLDDQGQINQFNQNTQEIVDLQNQLLDVNK-EKEQLLND--NIQLQNEF----GNEKQ 795 Query: 678 LALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLA 737 ++EN K+D + K LE + + LQ Y + DKL K + ++ EL + Sbjct: 796 ---ILEN-KVDDQS-----KKLEQYENE----LQQYKTNQLQFNDKL-KQAQRQLVELQS 841 Query: 738 KINHEE------QSKIQTQFGIDAKIQERDLYIENIESELS-KYKSRICRLEESIAVME- 789 ++ E+ QS++Q+ + +Q+ ++ ES++S + ++ + ++ E+I+ E Sbjct: 842 ELQEEQIKSLQLQSQLQSISENKSSLQQNQDLLDIFESQISPRQQATVQQMTETISYTES 901 Query: 790 ----DRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIE 845 D+ + L+++ QL +QEK ++ Q++E+ + L V ++ E +L++ Sbjct: 902 VQQQDQLHLLKQQIQQLQEIIQEKDLEINQVIQQKNEMESSLDVAIEKMNNQENLILQLN 961 Query: 846 HENKEL--QKKNQILLEENQNLQISLSDMQ-QHYNALVEKANRTDLAESESTKYQTQLRD 902 EN +L ++K++I +Q +IS +M Q + +E DL + E Y+ + ++ Sbjct: 962 QENGKLIEEQKSEI---NHQKQKISSQEMVIQSLQSQIE-----DL-QQELQGYENKQKE 1012 Query: 903 LESNL-KRITHEHQ-----TLIVQKKKEIEDLEIEFNTQIE--SAIRDKKVLNEKYEKNI 954 E N+ K+I ++Q LI +K +EI+ L + N E +++K VL+ + +++ Sbjct: 1013 QEDNIQKKILEQNQEQQLKKLIAEKDQEIQSLREQLNKIHEQFDQLQNKSVLSNRSKRSF 1072 Query: 955 EYVTQLEAQLQEYKN-NIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINK 1013 + A+ ++++ N E N +E+ + + E + +++Q + D +Q +I Sbjct: 1073 QV-----AKFDQFRDINEEENNEELEDEDDLKFE--NMILKEQINKKEDLIKQQEQQIKS 1125 Query: 1014 LNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQ-RVSKQLL 1072 N +K ++ Q + N + + + ++ + + M E+ + +++K ++ Sbjct: 1126 FNEQDNEKSQQTEKEKQLLQNQNELLLQEIDKMQKEMEKLKEEQRRMLEQFELQMNKSVI 1185 Query: 1073 DSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXX 1132 ++ + QI Q DQ ++L + + + E + + + SD + Sbjct: 1186 SNRSKRSQNQI----QYDQFQDLPDDNSQGSQDEDENEELNLFVLQKKTSDQQKQIQNLQ 1241 Query: 1133 XXXXXXXXXLKVQEEEEFIQER-SVLQEQSAKLNTELQE 1170 K++EE +QE +VL+ +S L ++E Sbjct: 1242 ETIQ------KLKEENNSLQEEINVLKNKSVPLKPNVEE 1274 Score = 107 bits (258), Expect = 2e-21 Identities = 178/933 (19%), Positives = 409/933 (43%), Gaps = 88/933 (9%) Query: 647 ISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENL--KLDKEQLYGTIKDLENDKE 704 I+ LQ+ Q +I+++ L I +LS + +I+ L ++D Q T +D + +E Sbjct: 139 IAGLQNVQDQMKIENISLSNTIKSLSQQLSDARYIIQRLYSQVDLNQQQDT-QDNNSTQE 197 Query: 705 D--IMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKI--QER 760 + + + QN+I ++ ++ S E E + KI ++ +KI + ID + R Sbjct: 198 NNLVFYEYQNFILRQLNELEQQTLQSLELKEEKMLKIM-KKLNKINRKQQIDEDLLSSAR 256 Query: 761 DLYIENIESELSKYKSRICRLEESIAVM---EDRRYSLERKADQLGSYLQEKQKAYSEYT 817 + + I +EL + K + + +++ + E ++ S E+K +Q Q+ ++ ++E+ Sbjct: 257 QIDSKTIINELKQDKQNLLQKVKNLEIQLKQEQKKPSYEQKLNQA----QQIEEQFNEFK 312 Query: 818 IQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYN 877 + +++ L + +EK+ L KE Q+K +++ ++ I+L D + + Sbjct: 313 KKHQQIIYNLE--QEKSTSLEKEQLI----KKEAQQK----IKKLESQLIALMDELEGRD 362 Query: 878 ALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIE 937 ++E N+T ++ Q ++ L + LK E++ + ++I+ ++ NT I Sbjct: 363 QIIESLNQTINQNKNQSQKQQDVQQLINKLK----ENEQIQQDLNQQIQLMKKNNNT-IL 417 Query: 938 SAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQ 997 + + + KV +K K +Y T L+ Q K L ++ +N+ + ID + Q Sbjct: 418 NELENSKVEVQKIRK--DYST-LQGQFDYTKQENTELIKKIQYVNQQKQQSIDSLNDQWQ 474 Query: 998 TQSPDYTEQY-INEIN--KL----NALLKQKD--EEIIALNQKINNAQVSYMSMVSDYES 1048 + +EQ INE KL N L KQK E + L +K +++ ++ + Sbjct: 475 IHNEKLSEQLAINEDKYAKLSINYNQLSKQKQDLETQLKLKEKELESKLEELTEFEQLQL 534 Query: 1049 KLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPK 1108 ++ + ++N+ ++ Q+ L+ + ++ + +++ +++K+L + L ++ K Sbjct: 535 RVNKQNQTIQNLAQQNQQYEATLVKNIDEKKQFEKQIQDLMEKLKDLSQDNLNQQLLSDK 594 Query: 1109 TEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTEL 1168 + I+ ++ + + K + + IQ L++Q A N E+ Sbjct: 595 I--VKYQQEIDKLNKQNSRLLNEKNELQESIKNEK-DKSDLLIQNLEKLEDQLALANQEI 651 Query: 1169 QECYTKIIQLETLNTELTGH-DVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSI--- 1224 +E KI + + N +L D + + LK + E+ +N+NLL +A +++ Sbjct: 652 EEQTQKITKYQKENLDLLKQMDELTAKNKKLLKEQNEEWEEQNNNLLQKLALSENNLLNL 711 Query: 1225 --SSAVDQRGFEIAELWKQHLAQREADFQKTEHEL--RVQLSAFESKYEQLLDSVQSSTQ 1280 + +R E ++++ +++ + +L + Q++ F ++++D Sbjct: 712 QQKNTNQERIIEKLQVFEIENQKKDDYILNLKQQLDDQGQINQFNQNTQEIVDLQNQLLD 771 Query: 1281 EETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXX 1340 K + LQN+ ++++ L N + + + Q E + + ++ F Sbjct: 772 VNKEKEQLLNDNIQLQNEFGNEKQILENKVDDQSKKLEQYENELQQYKTNQLQFNDKLKQ 831 Query: 1341 XXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEA 1400 +L+ E Q+Q Q + +I+E + L+++ R +A Sbjct: 832 AQRQLVELQSELQEEQIKSLQLQSQ-LQSISENKSSLQQNQDLLDIFESQISPR---QQA 887 Query: 1401 KVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELA 1460 V ++T + +S Q+ D+ ++QQ+ ++++++ EK+ E+ Sbjct: 888 TVQQMTETISYTES-------------VQQQDQLHLLKQQI----QQLQEIIQEKDLEI- 929 Query: 1461 ILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTN 1520 N + E E IE++N + + LN+ E K +EE+ ++ N Sbjct: 930 ----------NQVIQQKNEMESSLDVAIEKMNNQENLILQLNQ---ENGKLIEEQKSEIN 976 Query: 1521 EMQTALENQEIEIVTLNDEITNLQNMVRASSSK 1553 + + +QE+ I +L +I +LQ ++ +K Sbjct: 977 HQKQKISSQEMVIQSLQSQIEDLQQELQGYENK 1009 Score = 98.7 bits (235), Expect = 1e-18 Identities = 182/952 (19%), Positives = 392/952 (41%), Gaps = 66/952 (6%) Query: 610 ETRLKAISLLESQKFDLVQEL----HILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLE 665 + +++ ISL + K L Q+L +I+Q+ Y +V+ L Q + E V E Sbjct: 148 QMKIENISLSNTIK-SLSQQLSDARYIIQRLYSQVD--LNQQQDTQDNNSTQENNLVFYE 204 Query: 666 EQIDALSASKKELALVIENLKLDKEQLYGTIKDLE--NDKEDIMNKLQNYIQENMDLTDK 723 Q L + +++L+L +E++ +K L N K+ I L + ++ +D Sbjct: 205 YQNFILRQLNELEQQTLQSLELKEEKMLKIMKKLNKINRKQQIDEDLLSSARQ-IDSKTI 263 Query: 724 LEKMSAEKISELLAKI-NHEEQSKI-QTQFGIDAKIQERDLYIENIESELSKYKSRICRL 781 + ++ +K LL K+ N E Q K Q + + K+ + E K++ I L Sbjct: 264 INELKQDK-QNLLQKVKNLEIQLKQEQKKPSYEQKLNQAQQIEEQFNEFKKKHQQIIYNL 322 Query: 782 EESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQL 841 E+ + ++ ++++A Q L+ + A + D+++ L ++ ++ ++ Sbjct: 323 EQEKSTSLEKEQLIKKEAQQKIKKLESQLIALMDELEGRDQIIESLNQTINQNKNQSQKQ 382 Query: 842 LEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLR 901 +++ +L++ QI + NQ +Q+ + N L + + Q Q Sbjct: 383 QDVQQLINKLKENEQIQQDLNQQIQLMKKNNNTILNELENSKVEVQKIRKDYSTLQGQFD 442 Query: 902 DLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEK-NIEYVTQL 960 + + + Q + QK++ I+ L ++ E + +KY K +I Y QL Sbjct: 443 YTKQENTELIKKIQYVNQQKQQSIDSLNDQWQIHNEKLSEQLAINEDKYAKLSINY-NQL 501 Query: 961 EAQLQEYKNNI----ENLNMNVEELNKMNLELIDKHVQKQQTQS-PDYTEQYINEINKLN 1015 Q Q+ + + + L +EEL + + + Q Q Q+ +QY + K Sbjct: 502 SKQKQDLETQLKLKEKELESKLEELTEFEQLQLRVNKQNQTIQNLAQQNQQYEATLVKNI 561 Query: 1016 ALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSK 1075 KQ +++I L +K+ + +S + K+ ++E+ +++KQ Sbjct: 562 DEKKQFEKQIQDLMEKLKD--------LSQDNLNQQLLSDKIVKYQQEIDKLNKQNSRLL 613 Query: 1076 QHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXX 1135 ELQ ++ + D+ L + E + I T + N+D Sbjct: 614 NEKNELQESIKNEKDKSDLLIQNLEKLEDQLALANQEIEEQTQKITKYQKENLDLLKQMD 673 Query: 1136 XXXXXXLKV--QEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQ 1193 K+ ++ EE+ ++ + L ++ A L K E + +L ++ NQ Sbjct: 674 ELTAKNKKLLKEQNEEWEEQNNNLLQKLALSENNLLNLQQKNTNQERIIEKLQVFEIENQ 733 Query: 1194 EQ---INQLKSKLE---QLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQRE 1247 ++ I LK +L+ Q+N N N + +L++ + ++ +L ++ Q + Sbjct: 734 KKDDYILNLKQQLDDQGQINQFNQN-TQEIVDLQNQLLDVNKEK----EQLLNDNI-QLQ 787 Query: 1248 ADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLR 1307 +F + L ++ K EQ + +Q Q +TN++ +++ Q +L + + L+ Sbjct: 788 NEFGNEKQILENKVDDQSKKLEQYENELQ---QYKTNQLQFNDKLKQAQRQLVELQSELQ 844 Query: 1308 NLQEKYADVINQIEIL---RSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSY-KQMQ 1363 Q K + +Q++ + +S ++ + + TE SY + +Q Sbjct: 845 EEQIKSLQLQSQLQSISENKSSLQQNQDLLDIFESQISPRQQATVQQM-TETISYTESVQ 903 Query: 1364 EQSILN-INEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHE 1422 +Q L+ + ++ QL++ + N+ E+ + ++ +++ I Q E Sbjct: 904 QQDQLHLLKQQIQQLQEIIQEKDLEINQVIQQKNEMESSLDVAIEKMNNQENLILQLNQE 963 Query: 1423 YTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEI 1482 + ++ E + +Q++ E I+ L + E + + YE QKE E Sbjct: 964 NGKLIEEQKSEINHQKQKISSQEMVIQSLQSQIED--------LQQELQGYENKQKEQED 1015 Query: 1483 ERVKLIEELNVKITESVSLNKQVAELN---KALEEEVAKTNEMQTALENQEI 1531 K I E N + L K +AE + ++L E++ K +E L+N+ + Sbjct: 1016 NIQKKILEQN----QEQQLKKLIAEKDQEIQSLREQLNKIHEQFDQLQNKSV 1063 Score = 72.1 bits (169), Expect = 1e-10 Identities = 124/662 (18%), Positives = 281/662 (42%), Gaps = 56/662 (8%) Query: 951 EKNIEYVTQLEAQLQEYKNNIENLNM--NVEELNKMNLELIDKHVQKQQTQSPDYTEQYI 1008 +K +Y Q + Q N + L N E+ K + +LI+ Q + SP Sbjct: 47 KKTQDYQFQFKNQTNNQDNYLTFLKSGKNGEQFQKTH-QLINP--QNLRYLSPSNINTAK 103 Query: 1009 NEINKLNALLKQKD---EEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQ 1065 N+ + N +Q+D +EI L + + ++ Y + ++ ++ Q + ++ ++ Sbjct: 104 NDCEQNN--FQQQDNSFQEIADLKIRNDKTRMFYQTQIAGLQNVQDQMKIENISLSNTIK 161 Query: 1066 RVSKQLLDSKQHNEELQILVREQD-DQIKELKETKLTFEMNIP--KTEGMIISSTIEPMS 1122 +S+QL D++ +Q L + D +Q ++ ++ T E N+ + + I+ E Sbjct: 162 SLSQQLSDARYI---IQRLYSQVDLNQQQDTQDNNSTQENNLVFYEYQNFILRQLNELEQ 218 Query: 1123 DDANNVDXXXXXXXXXXXXL-KVQEEEEFIQE--RSVLQEQSAKLNTELQECYTKIIQ-L 1178 +++ L K+ +++ ++ S Q S + EL++ ++Q + Sbjct: 219 QTLQSLELKEEKMLKIMKKLNKINRKQQIDEDLLSSARQIDSKTIINELKQDKQNLLQKV 278 Query: 1179 ETLNTELTGHDVVN--QEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIA 1236 + L +L ++++NQ + EQ N + L S+++++ Sbjct: 279 KNLEIQLKQEQKKPSYEQKLNQAQQIEEQFNEFKKKHQQIIYNLEQEKSTSLEKE----- 333 Query: 1237 ELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQ 1296 +L K+ Q+ +K E +L + E + +Q+++S+ + + N+ + V L Sbjct: 334 QLIKKEAQQK---IKKLESQLIALMDELEGR-DQIIESLNQTINQNKNQSQKQQDVQQLI 389 Query: 1297 NKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXX------XXXXXX 1350 NKL++ E+ ++L ++ + + +E+E+ KV Sbjct: 390 NKLKENEQIQQDLNQQIQLMKKNNNTILNELENSKVEVQKIRKDYSTLQGQFDYTKQENT 449 Query: 1351 DLRTENQSYKQMQEQSILNINEE----NAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELT 1406 +L + Q Q ++QSI ++N++ N +L + N + +L Sbjct: 450 ELIKKIQYVNQQKQQSIDSLNDQWQIHNEKLSEQLAINEDKYAKLSINYNQLSKQKQDLE 509 Query: 1407 HQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKM 1466 QL+LK+ E+ K E T EFE ++ ++ + + I++L + + A L + Sbjct: 510 TQLKLKEKELESKLEELT--------EFEQLQLRVNKQNQTIQNLAQQNQQYEATLVKNI 561 Query: 1467 HENANHYETMQKESEIERVKLIEELNVKITES--VSLNKQVAELNKALEEEVAKTNEMQT 1524 E + +Q E + + LN ++ V +++ +LNK + + NE+Q Sbjct: 562 DEKKQFEKQIQDLMEKLKDLSQDNLNQQLLSDKIVKYQQEIDKLNKQNSRLLNEKNELQE 621 Query: 1525 ALENQEIEIVTLNDEITNLQNMVRASSSKIQKHV-SFASDTKQGRD--EQLD--NTMNKE 1579 +++N++ + L + L++ + ++ +I++ K+ D +Q+D NK+ Sbjct: 622 SIKNEKDKSDLLIQNLEKLEDQLALANQEIEEQTQKITKYQKENLDLLKQMDELTAKNKK 681 Query: 1580 LL 1581 LL Sbjct: 682 LL 683 >UniRef50_Q22RB5 Cluster: Putative uncharacterized protein; n=1; Tetrahymena thermophila SB210|Rep: Putative uncharacterized protein - Tetrahymena thermophila SB210 Length = 1852 Score = 147 bits (356), Expect = 3e-33 Identities = 246/1229 (20%), Positives = 525/1229 (42%), Gaps = 96/1229 (7%) Query: 400 KKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLE---- 455 KKI K+ ++L+ + Q +NK V + + K+ ++QL+ Sbjct: 355 KKIKKDYESQLKDISQKINKR--SGSIVRLDSISEIEKLREQLEHKEKELSQLKSNTFEL 412 Query: 456 HQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQL 515 + + LI + E EIA+ Q ++ QE + ++ L + L ++E+ L Sbjct: 413 SPKSYQAKELIGESADGEYNFEIAENQFKINQEQQQNFLN-DLSKLEQTLLQSQEREEVL 471 Query: 516 NDEIDAANKNMIKVKSNHKLKLKQMQ-KTIDNFSKVSDSNKEIVRLTEELHHLSQKVAEL 574 N ++ N+N K + K +L+ ++ K+ ++ EI +E HL Q+++ Sbjct: 472 NAKVKQQNENFDKEINELKTQLQSLKSKSEFQEQELQKYQNEIQAKNQEFQHLKQQISMA 531 Query: 575 EEE----KGNLQLHLVDY-----DSGRMIESDVYKKMIEM-ENLAETRLKAISLLESQKF 624 EE+ K ++ +Y D + IE+ YKK IE+ E+ + + S E + Sbjct: 532 EEKEKTVKDQMEQDKNNYLNQINDFNQQIEN--YKKQIELNESQIHNQQTSSSQKEEEIN 589 Query: 625 DLVQELHILQQKYD---EVEDK--LADISQLQSDQVCSEIKSVHLEEQIDALSASKKELA 679 L + + ++K E ++K + +S ++ E + + + + ++ E+ Sbjct: 590 RLYENMKNEKEKISLALEQKEKGHILILSNMEEQLKIKESQLIDVRKIQESEKIKLTEMV 649 Query: 680 LVIENLK-LDKEQLYGTIKDLENDKEDIMNKLQNY---IQENMDLTDKLEKMSAEKISEL 735 +E LK + E+ I+ + N +E I + +NY + E D E E+I E+ Sbjct: 650 EKVEELKKILSEKSSKEIELVRNHEEAIQKERENYEVLLTEKQKQWDIKENNFNEQIKEV 709 Query: 736 LAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSL 795 K++ EQ+K + + + + + I ++ES+L ++ + E+ I ++ L Sbjct: 710 NEKMSKLEQTKSEEKKNLTNQNSQLQASILSLESKLKSESEKLAQSEQQIKKLQMSSSDL 769 Query: 796 ----ERKADQLGSY----------LQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQL 841 K GS L+E+ K E IQ + L + + + L Sbjct: 770 INDQNSKITAFGSQVEGLLLEIAALKEQNKKQKELEIQIENLSCQNKKMENELNKKAMNL 829 Query: 842 LEIEHENKELQKKNQILLEENQNLQISLSDMQQHYN---ALVEK-----ANRTDLAESES 893 ++E + K+L+K+ +IL E+ Q + S S +Q N AL+++ + E++S Sbjct: 830 QQVEEQEKDLKKQLKILEEKIQEHESSFSALQLAENEKQALLKQEIASLGEKIKEIETQS 889 Query: 894 TKYQTQLRDLESNLKRITHEHQTL---IVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKY 950 K + ++ +LE +L I L +V++K E LE+ + + E ++K+VL Sbjct: 890 DKRKEKIGELEKSLAEIQQVKSALEEQMVKQKSEFSSLELVLSQERE---KNKEVLANMK 946 Query: 951 EKNIEYVTQLEAQLQEYKNNIE-NLNMNVEELNKMNL-ELIDKHVQKQQTQSPDYTEQYI 1008 +++ + + E Q+ + K E L +E + L E I++ ++ Q Q+ + +E+ Sbjct: 947 KQSQKEKEEFENQISQQKEQHEIKLRETLEANSGKELQEQIEQIKEQYQKQNKELSEK-C 1005 Query: 1009 NEIN-KLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRV 1067 NE+N KL + +++++E+ + +++N S SM+ +E + + EN E +++ Sbjct: 1006 NELNLKLESQKQEREKEVTEMKEQLNQKGESIHSMIKKHEEDVINQKKQFEN---EKEKL 1062 Query: 1068 SKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANN 1127 +KQ D K +L+ ++ ++ Q L+ + + + E + E Sbjct: 1063 TKQFNDEKS---QLESQLQGKETQFIALQSQLSLVQQELQEKEKQKKNQEQEHQKI-CRQ 1118 Query: 1128 VDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTG 1187 ++ + Q +E+ S+L+E + ++ Y + + ETLN++L+ Sbjct: 1119 LENTIAENKAQIESINKQNDEKI---SSLLEENILNVKN-IEARYVQ--EKETLNSQLSE 1172 Query: 1188 HDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQ---HLA 1244 D + +INQ++ +L + + + L L ++ + Q+ + E +Q Sbjct: 1173 QDKQIKVKINQIQEELSKKISSFEELNQQFVSLEEEKNN-LKQQILSLEEEKQQLDLQTK 1231 Query: 1245 QREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEE 1304 Q++ +F++ E Q+ +E + +Q+ E +K+V + + + K E Sbjct: 1232 QKQQEFEEKELNREKQIEEINKNHEIQMQKMQT---ELDSKVVLINAANVQLVQAKSKIE 1288 Query: 1305 HLRNLQEKY-ADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQ 1363 +NL + AD+ QI+I +E ++ ENQS + Sbjct: 1289 EYKNLYSSHKADLEKQIQI--NEEREQSFLNKEKEWKEKLDQKNLTLSAFYENQSQISQK 1346 Query: 1364 EQSILN--INEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTH 1421 + I I + Q+ + + + A+ +E Q E+K E K Sbjct: 1347 NEEIQQQRIKQYEQQMTQVQSRFENDIQQLQAK-HSADISSIEQKFQQEIKQMESKLKQQ 1405 Query: 1422 E--YTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKE 1479 E + L Q+ D+ E Q ++ ++ +KE ++ ++++ ++M E Sbjct: 1406 EILHEQLLKQQKDQLEQEHNQEIQ---SLQSEVNQKEDKINQSLTQINQLQAQIDSMNNE 1462 Query: 1480 SEIERVKLI--EELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLN 1537 + K+I E+ + ++ + ++ K E+ +E V K + Q N+EI + +N Sbjct: 1463 KKESTNKIIALEKESAQLKQKLTEIKNPEEIQHQKDEGVLKQQQQQIQKLNEEI--ILIN 1520 Query: 1538 DEITNLQNMVRASSSKIQKHVSFASDTKQ 1566 ++ + +R +Q + A+D Q Sbjct: 1521 NQKNQYEQEIRQLKLTLQNSIKSANDLDQ 1549 Score = 141 bits (342), Expect = 1e-31 Identities = 251/1237 (20%), Positives = 536/1237 (43%), Gaps = 125/1237 (10%) Query: 228 MEAEWKDEKQRLL---KDIESKDVRISSL----EEANKLL-EAARFEISL--EHSKLAQE 277 ME + K ++ +L+ K ES+ ++++ + EE K+L E + EI L H + Q+ Sbjct: 620 MEEQLKIKESQLIDVRKIQESEKIKLTEMVEKVEELKKILSEKSSKEIELVRNHEEAIQK 679 Query: 278 LEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQ 337 + + + + E+ E+ EK S +E K L + N Q Sbjct: 680 ERENYEVLLTEKQKQWDIKENNFN---EQIKEVNEKMSKLEQTKSEEKKN---LTNQNSQ 733 Query: 338 IRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQD 397 ++ + LE+KL + +E A S K + S + SK+ + SQ+ L Sbjct: 734 LQASILSLESKLKSE-SEKLAQSEQQIKKLQMSSSDLINDQNSKITAFGSQVEGLLLEIA 792 Query: 398 TDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQ 457 K+ NK + +LE+ I++L+ E +++K + L+ + Q Sbjct: 793 ALKEQNKKQ-KELEIQIENLSCQNKKMENELNKKAMNLQQVEEQEKDLKKQLKILEEKIQ 851 Query: 458 QHMEGPSLIHVGTNTEDV---NEIAKVQEQLKQ-ELNDEIKDVNVKDL------IEKLKS 507 +H S + + N + EIA + E++K+ E + + + +L I+++KS Sbjct: 852 EHESSFSALQLAENEKQALLKQEIASLGEKIKEIETQSDKRKEKIGELEKSLAEIQQVKS 911 Query: 508 A-EEQITQLNDEIDAANKNMIKVKSNHKLKL----KQMQKTIDNFSKVSDSNKEI--VRL 560 A EEQ+ + E + + + + +K L KQ QK + F KE ++L Sbjct: 912 ALEEQMVKQKSEFSSLELVLSQEREKNKEVLANMKKQSQKEKEEFENQISQQKEQHEIKL 971 Query: 561 TEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLE 620 E L S K EL+E+ ++ + + + +++E+ + R K ++ ++ Sbjct: 972 RETLEANSGK--ELQEQIEQIKEQY--QKQNKELSEKCNELNLKLESQKQEREKEVTEMK 1027 Query: 621 SQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELAL 680 Q + +H + +K++E D + Q ++++ + + Q+++ K+ + Sbjct: 1028 EQLNQKGESIHSMIKKHEE--DVINQKKQFENEKEKLTKQFNDEKSQLESQLQGKETQFI 1085 Query: 681 VIEN-LKLDKEQLYGTIKDLENDKED---IMNKLQNYIQENMDLTDKLEKMSAEKISELL 736 +++ L L +++L K +N +++ I +L+N I EN + + K + EKIS LL Sbjct: 1086 ALQSQLSLVQQELQEKEKQKKNQEQEHQKICRQLENTIAENKAQIESINKQNDEKISSLL 1145 Query: 737 AK----INHEEQSKIQTQFGIDAKIQERD----LYIENIESELSKYKSRICRLEESIAVM 788 + + + E +Q + +++++ E+D + I I+ ELSK S L + + Sbjct: 1146 EENILNVKNIEARYVQEKETLNSQLSEQDKQIKVKINQIQEELSKKISSFEELNQQFVSL 1205 Query: 789 EDRR-------YSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQL 841 E+ + SLE + QL ++KQ+ + E + ++ + + +H+ ++K Sbjct: 1206 EEEKNNLKQQILSLEEEKQQLDLQTKQKQQEFEEKELNREKQIEEIN--KNHEIQMQKMQ 1263 Query: 842 LEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLR 901 E++ + + N L++ ++ ++ + A +EK + + E + + + Sbjct: 1264 TELDSKVVLINAANVQLVQAKSKIE-EYKNLYSSHKADLEK--QIQINEEREQSFLNKEK 1320 Query: 902 DLESNL--KRIT----HEHQTLIVQKKKEIEDLEI----EFNTQIESAIR-DKKVLNEKY 950 + + L K +T +E+Q+ I QK +EI+ I + TQ++S D + L K+ Sbjct: 1321 EWKEKLDQKNLTLSAFYENQSQISQKNEEIQQQRIKQYEQQMTQVQSRFENDIQQLQAKH 1380 Query: 951 EKNIEYVTQ-LEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYIN 1009 +I + Q + ++++ ++ ++ + E+L K + +++ ++ Q + Sbjct: 1381 SADISSIEQKFQQEIKQMESKLKQQEILHEQLLKQQKDQLEQEHNQEIQSLQSEVNQKED 1440 Query: 1010 EINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSK 1069 +IN+ + Q +I ++N + + +++ + ++L Q T+++N EE + + Sbjct: 1441 KINQSLTQINQLQAQIDSMNNEKKESTNKIIALEKE-SAQLKQKLTEIKNPEEIQHQKDE 1499 Query: 1070 QLLDSKQH-----NEELQILVREQDDQIKELKETKLTFEMNIPKTEGM------------ 1112 +L +Q NEE+ ++ +++ +E+++ KLT + +I + Sbjct: 1500 GVLKQQQQQIQKLNEEIILINNQKNQYEQEIRQLKLTLQNSIKSANDLDQEISNYQAFRN 1559 Query: 1113 -IISSTI-EPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQE 1170 S +I E S + NV L +E EFI R S ++ +LQ Sbjct: 1560 SYSSQSIHEAESSHSLNVSPTHIPKLNMMA-LSNRETNEFISPRGPASANSKQIELQLQ- 1617 Query: 1171 CYTKIIQLETLNTELTG--HDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAV 1228 + LE N EL H ++IN KL + N ++ L T +L+ S + Sbjct: 1618 ----VKSLENKNKELKESLHQFNQVQKINTEMKKLLEENRKSIKELETELQLKKSDN--- 1670 Query: 1229 DQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKI-- 1286 +Q EI Q L + DF+ E +L +++EQ+ D + + +KI Sbjct: 1671 EQMKTEI-----QKLKEALIDFESFEEKLLEMRQIDMNRFEQVRDKIDDLKEVSQSKIEL 1725 Query: 1287 VTMEQVTSL--QNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXX 1344 V + Q+ +L + +L D+ E ++ +Y I ++ I EI+++ Sbjct: 1726 VNIIQMFALNFKKELDDRNEKIK----QYLKKIEKVSIQFREIQEQ----HQEMEQLLLS 1777 Query: 1345 XXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSS 1381 + +NQ Q Q+ ++ N +++ + S Sbjct: 1778 NKIEISHIVDQNQKNSQYQQNTLYRSNSQSSDFDRRS 1814 Score = 135 bits (327), Expect = 8e-30 Identities = 234/1148 (20%), Positives = 481/1148 (41%), Gaps = 87/1148 (7%) Query: 470 TNTEDVNEIAKVQEQLKQELNDEI--KDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMI 527 T + + ++ QEQ Q+ +EI K+ + L +++ AEE+ + D+++ N + Sbjct: 491 TQLQSLKSKSEFQEQELQKYQNEIQAKNQEFQHLKQQISMAEEKEKTVKDQMEQDKNNYL 550 Query: 528 KVKSNHKLKLKQMQKTID-NFSKV-------SDSNKEIVRLTEELHHLSQKVA-ELEE-E 577 ++ +++ +K I+ N S++ S +EI RL E + + +K++ LE+ E Sbjct: 551 NQINDFNQQIENYKKQIELNESQIHNQQTSSSQKEEEINRLYENMKNEKEKISLALEQKE 610 Query: 578 KGNL--------QLHLVDYD--SGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLV 627 KG++ QL + + R I+ K+ EM E K +S S++ +LV Sbjct: 611 KGHILILSNMEEQLKIKESQLIDVRKIQESEKIKLTEMVEKVEELKKILSEKSSKEIELV 670 Query: 628 QELHILQQKYDEVEDKLADISQLQSD----QVCSEIKSVHLEEQIDALSASKKELALVIE 683 + QK E + L Q Q D +IK V+ E++ L +K E + Sbjct: 671 RNHEEAIQKERENYEVLLTEKQKQWDIKENNFNEQIKEVN--EKMSKLEQTKSEEK---K 725 Query: 684 NLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEE 743 NL QL +I LE+ + KL Q+ L + ++ S++ A + E Sbjct: 726 NLTNQNSQLQASILSLESKLKSESEKLAQSEQQIKKLQMSSSDLINDQNSKITAFGSQVE 785 Query: 744 QS--KIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQ 801 +I + K +E ++ IEN+ + K ++ + + ++ +E++ L+++ Sbjct: 786 GLLLEIAALKEQNKKQKELEIQIENLSCQNKKMENELNKKAMNLQQVEEQEKDLKKQLKI 845 Query: 802 LGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEE 861 L +QE + ++S + E+E + A+L + +++ EIE ++ + ++K L + Sbjct: 846 LEEKIQEHESSFSALQLAENE---KQALLKQEIASLGEKIKEIETQSDKRKEKIGELEKS 902 Query: 862 NQNLQISLSDMQQHYNALVEKANRTDLAES-ESTKYQTQLRDLESNLKRITHEHQTLIVQ 920 +Q S +++ + + +L S E K + L +++ ++ E + I Q Sbjct: 903 LAEIQQVKSALEEQMVKQKSEFSSLELVLSQEREKNKEVLANMKKQSQKEKEEFENQISQ 962 Query: 921 KKK--EI---EDLEIEFNTQIESAIRDKKVLNEKYEKNI-EYVTQLEAQLQEYKNNIENL 974 +K+ EI E LE +++ I K +K K + E +L +L+ K E Sbjct: 963 QKEQHEIKLRETLEANSGKELQEQIEQIKEQYQKQNKELSEKCNELNLKLESQKQEREKE 1022 Query: 975 NMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINN 1034 ++E E I ++K + + +Q+ NE KL + ++ + Q Sbjct: 1023 VTEMKEQLNQKGESIHSMIKKHEEDVINQKKQFENEKEKLTKQFNDEKSQLESQLQGKET 1082 Query: 1035 AQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNE-ELQILVREQDDQIK 1093 ++ S +S + +L + + +N E+E Q++ +QL ++ N+ +++ + ++ D++I Sbjct: 1083 QFIALQSQLSLVQQELQEKEKQKKNQEQEHQKICRQLENTIAENKAQIESINKQNDEKIS 1142 Query: 1094 ELKETKLTFEMNI-------PKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQ- 1145 L E + NI +T +S + + N + L Q Sbjct: 1143 SLLEENILNVKNIEARYVQEKETLNSQLSEQDKQIKVKINQIQEELSKKISSFEELNQQF 1202 Query: 1146 ---EEEEFIQERSVLQEQSAKLNTEL------QECYTKIIQLETLNTELT-GHDVVNQEQ 1195 EEE+ ++ +L + K +L QE K + E E+ H++ Q+ Sbjct: 1203 VSLEEEKNNLKQQILSLEEEKQQLDLQTKQKQQEFEEKELNREKQIEEINKNHEIQMQKM 1262 Query: 1196 INQLKSKLEQLNTENDNLL---STVAELRSSISS--AVDQRGFEIAELWKQHLAQREADF 1250 +L SK+ +N N L+ S + E ++ SS A ++ +I E +Q +E ++ Sbjct: 1263 QTELDSKVVLINAANVQLVQAKSKIEEYKNLYSSHKADLEKQIQINEEREQSFLNKEKEW 1322 Query: 1251 QKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKI-VTMEQVTS-LQNKLQD-KEEH-- 1305 ++ + + LSAF Q+ + Q+ + M QV S +N +Q + +H Sbjct: 1323 KEKLDQKNLTLSAFYENQSQISQKNEEIQQQRIKQYEQQMTQVQSRFENDIQQLQAKHSA 1382 Query: 1306 -LRNLQEKYADVINQIE--ILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQM 1362 + ++++K+ I Q+E + + EI E++ L++E + Sbjct: 1383 DISSIEQKFQQEIKQMESKLKQQEILHEQL-LKQQKDQLEQEHNQEIQSLQSEVNQKEDK 1441 Query: 1363 QEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDA---EAKVLELTHQLELKDSEIYQK 1419 QS+ IN+ AQ+ + ++ + K+ E+ + E++ + Sbjct: 1442 INQSLTQINQLQAQIDSMNNEKKESTNKIIALEKESAQLKQKLTEIKNPEEIQHQKDEGV 1501 Query: 1420 THEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANH--YETMQ 1477 + + + N+E + Q +YE+ I L ++ + E +N+ + Sbjct: 1502 LKQQQQQIQKLNEEIILINNQKNQYEQEIRQLKLTLQNSIKSANDLDQEISNYQAFRNSY 1561 Query: 1478 KESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEV-----AKTNEMQTALENQEIE 1532 I + LNV T LN +A N+ E + A N Q L+ Q Sbjct: 1562 SSQSIHEAESSHSLNVSPTHIPKLN-MMALSNRETNEFISPRGPASANSKQIELQLQVKS 1620 Query: 1533 IVTLNDEI 1540 + N E+ Sbjct: 1621 LENKNKEL 1628 Score = 123 bits (296), Expect = 5e-26 Identities = 189/908 (20%), Positives = 383/908 (42%), Gaps = 69/908 (7%) Query: 723 KLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRL- 781 K++K ++ ++ KIN S ++ ++I++ +E+ E ELS+ KS L Sbjct: 356 KIKKDYESQLKDISQKINKRSGSIVRLDS--ISEIEKLREQLEHKEKELSQLKSNTFELS 413 Query: 782 ------EESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRL-------A 828 +E I D Y+ E +Q +++Q ++ + E L+ A Sbjct: 414 PKSYQAKELIGESADGEYNFEIAENQFKINQEQQQNFLNDLSKLEQTLLQSQEREEVLNA 473 Query: 829 VLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDL 888 + + +K++ E++ + + L+ K++ +E Q Q + Q + L ++ + + Sbjct: 474 KVKQQNENFDKEINELKTQLQSLKSKSEFQEQELQKYQNEIQAKNQEFQHLKQQISMAE- 532 Query: 889 AESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNE 948 E E T +D + L +I +Q I KK+IE E + + Q S+ + ++ +N Sbjct: 533 -EKEKTVKDQMEQDKNNYLNQINDFNQQ-IENYKKQIELNESQIHNQQTSSSQKEEEINR 590 Query: 949 KYE--KNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELID-KHVQKQQTQSPDYTE 1005 YE KN + L + Q+ K +I L+ E+L +LID + +Q+ + Sbjct: 591 LYENMKNEKEKISLALE-QKEKGHILILSNMEEQLKIKESQLIDVRKIQESEKIKLTEMV 649 Query: 1006 QYINEINKLNALLKQKDEEII-----ALNQKINNAQVSYMSMVSDYESKLAQFTTKLENM 1060 + + E+ K+ + K+ E++ A+ ++ N +V ++ K F +++ + Sbjct: 650 EKVEELKKILSEKSSKEIELVRNHEEAIQKERENYEVLLTEKQKQWDIKENNFNEQIKEV 709 Query: 1061 EEEMQRVSKQLLDSKQH----NEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISS 1116 E+M ++ + + K++ N +LQ + + ++K E E I K + M S Sbjct: 710 NEKMSKLEQTKSEEKKNLTNQNSQLQASILSLESKLKSESEKLAQSEQQIKKLQ-MSSSD 768 Query: 1117 TIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSV--LQEQSAKLNTELQECYTK 1174 I + LK Q +++ E + L Q+ K+ EL + Sbjct: 769 LINDQNSKITAFGSQVEGLLLEIAALKEQNKKQKELEIQIENLSCQNKKMENELNKKAMN 828 Query: 1175 IIQLETLNTELTGHDVVNQEQINQLKSKLEQLN-TENDNL------LSTVAELRSSISSA 1227 + Q+E +L + +E+I + +S L EN+ ++++ E I + Sbjct: 829 LQQVEEQEKDLKKQLKILEEKIQEHESSFSALQLAENEKQALLKQEIASLGEKIKEIETQ 888 Query: 1228 VDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQE--ETNK 1285 D+R +I EL K LA+ + E ++ Q S F S E +L + +E K Sbjct: 889 SDKRKEKIGELEKS-LAEIQQVKSALEEQMVKQKSEF-SSLELVLSQEREKNKEVLANMK 946 Query: 1286 IVTMEQVTSLQNKL-QDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXX 1344 + ++ +N++ Q KE+H L+E N + L+ +IE K + Sbjct: 947 KQSQKEKEEFENQISQQKEQHEIKLRETLE--ANSGKELQEQIEQIKEQY----QKQNKE 1000 Query: 1345 XXXXXXDLRTENQSYKQMQEQSILNINEE-NAQLKKSSXXXXXXXXXXXXRVNDAEAKVL 1403 +L + +S KQ +E+ + + E+ N + + + E + Sbjct: 1001 LSEKCNELNLKLESQKQEREKEVTEMKEQLNQKGESIHSMIKKHEEDVINQKKQFENEKE 1060 Query: 1404 ELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILR 1463 +LT Q + S++ + + V+Q+L E EK+ ++ E + L Sbjct: 1061 KLTKQFNDEKSQLESQLQGKETQFIALQSQLSLVQQELQEKEKQKKNQEQEHQKICRQLE 1120 Query: 1464 LKMHENANHYETMQKESEIERVKLIEE--LNVK------ITESVSLNKQVAELNKALEEE 1515 + EN E++ K+++ + L+EE LNVK + E +LN Q++E +K ++ Sbjct: 1121 NTIAENKAQIESINKQNDEKISSLLEENILNVKNIEARYVQEKETLNSQLSEQDKQIK-- 1178 Query: 1516 VAKTNEMQTALENQEIEIVTLNDEITNLQ----NMVRASSSKIQKHVSFASDTKQGRDEQ 1571 K N++Q L + LN + +L+ N+ + S ++ TKQ + E Sbjct: 1179 -VKINQIQEELSKKISSFEELNQQFVSLEEEKNNLKQQILSLEEEKQQLDLQTKQKQQEF 1237 Query: 1572 LDNTMNKE 1579 + +N+E Sbjct: 1238 EEKELNRE 1245 Score = 107 bits (257), Expect = 2e-21 Identities = 212/1152 (18%), Positives = 475/1152 (41%), Gaps = 99/1152 (8%) Query: 152 KEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXX 211 K N S LQ + +E+ + EK+ + +Q I+ +++ Sbjct: 725 KNLTNQNSQLQASILSLESKLKSESEKLAQSEQQIKKLQMSSSDLINDQNSKITAFGSQV 784 Query: 212 EDT-------KQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAAR 264 E K+Q K +E I +E + +++ ++ K + + +EE K L+ Sbjct: 785 EGLLLEIAALKEQNKKQKELEIQIE-NLSCQNKKMENELNKKAMNLQQVEEQEKDLKK-- 841 Query: 265 FEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTEL 324 ++ + K+ QE E L KQ I E+ EIE + + EL Sbjct: 842 -QLKILEEKI-QEHESSFSALQLAENEKQALLKQEIASLGEKIKEIETQSDKRKEKIGEL 899 Query: 325 TKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKS 384 K + +I+Q LE ++ +E ++ + R+ + + MK Sbjct: 900 EKSL-------AEIQQVKSALEEQMVKQKSEFSSLELVLSQ-----EREKNKEVLANMKK 947 Query: 385 PWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXG 444 + E NQ + +K ++EI E + + K+L ++ I E+ Sbjct: 948 QSQKEKEEFENQISQQK-EQHEIKLRETLEANSGKELQEQIEQIKEQYQKQNKELSEKCN 1006 Query: 445 KDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEK 504 + L + Q + ++ + E ++ + K E+ +N + + N K+ + K Sbjct: 1007 ELNLKLESQKQEREKEVTEMKEQLNQKGESIHSMIKKHEE--DVINQKKQFENEKEKLTK 1064 Query: 505 LKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEEL 564 + E+ +QL ++ I ++S L +++Q+ +++I R Sbjct: 1065 QFNDEK--SQLESQLQGKETQFIALQSQLSLVQQELQEKEKQKKNQEQEHQKICR----- 1117 Query: 565 HHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKF 624 L +AE Q+ ++ + I S + + ++ ++N+ ++ L SQ Sbjct: 1118 -QLENTIAE-----NKAQIESINKQNDEKISSLLEENILNVKNIEARYVQEKETLNSQLS 1171 Query: 625 DLVQELHI-LQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIE 683 + +++ + + Q +E+ K++ +L V E + +L++QI +L K++L L + Sbjct: 1172 EQDKQIKVKINQIQEELSKKISSFEELNQQFVSLEEEKNNLKQQILSLEEEKQQLDLQTK 1231 Query: 684 NLKLDKEQLYGTIKDLENDKE-DIMNKLQNYIQENM--DLTDKLEKMSAEKISELLAKIN 740 + + E+ K+L +K+ + +NK + M +L K+ ++A + + AK Sbjct: 1232 QKQQEFEE-----KELNREKQIEEINKNHEIQMQKMQTELDSKVVLINAANVQLVQAKSK 1286 Query: 741 HEEQSKIQTQFGIDAK--IQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERK 798 EE + + D + IQ + ++ ++ ++K ++ + +++ + + + +K Sbjct: 1287 IEEYKNLYSSHKADLEKQIQINEEREQSFLNKEKEWKEKLDQKNLTLSAFYENQSQISQK 1346 Query: 799 ADQLGSYLQEKQKAYSEYTIQ-EDELVNRLAVLM-DHDRVVEKQLLEIEHENKELQKK-- 854 +++ Q++ K Y + Q + N + L H + + + E K+++ K Sbjct: 1347 NEEIQ---QQRIKQYEQQMTQVQSRFENDIQQLQAKHSADISSIEQKFQQEIKQMESKLK 1403 Query: 855 NQILLEENQNLQISLSDMQQHYNALVEKA-NRTDLAESESTKYQTQLRDLESNLKRITHE 913 Q +L E Q L+ ++Q +N ++ + + E + + TQ+ L++ + + +E Sbjct: 1404 QQEILHE-QLLKQQKDQLEQEHNQEIQSLQSEVNQKEDKINQSLTQINQLQAQIDSMNNE 1462 Query: 914 HQ---TLIVQKKKEIEDL-----EIEFNTQIESAIRDKKVLNEKYE---KNIEYVTQLEA 962 + I+ +KE L EI+ +I+ +D+ VL ++ + K E + + Sbjct: 1463 KKESTNKIIALEKESAQLKQKLTEIKNPEEIQHQ-KDEGVLKQQQQQIQKLNEEIILINN 1521 Query: 963 QLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKD 1022 Q +Y+ I L + ++ K +L D+ + Q Y+ Q I+E ++L Sbjct: 1522 QKNQYEQEIRQLKLTLQNSIKSANDL-DQEISNYQAFRNSYSSQSIHEAESSHSLNVSPT 1580 Query: 1023 E----EIIALNQKINNAQVSYMSMVSDYESKLA-QFTTK-LENMEEEMQRVSKQLLDSKQ 1076 ++AL+ + N +S S ++ Q K LEN +E++ Q ++ Sbjct: 1581 HIPKLNMMALSNRETNEFISPRGPASANSKQIELQLQVKSLENKNKELKESLHQFNQVQK 1640 Query: 1077 HNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXX 1136 N E++ L+ E IKEL ET E+ + K++ + + I+ + + + + Sbjct: 1641 INTEMKKLLEENRKSIKEL-ET----ELQLKKSDNEQMKTEIQKLKEALIDFE----SFE 1691 Query: 1137 XXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQI 1196 ++ + F Q R + + ++++ IIQ+ LN + D E+I Sbjct: 1692 EKLLEMRQIDMNRFEQVRDKIDDLKEVSQSKIE--LVNIIQMFALNFKKELDD--RNEKI 1747 Query: 1197 NQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQK-TEH 1255 Q K+E+++ + + E + + EI+ + Q+ Q+ + +Q+ T + Sbjct: 1748 KQYLKKIEKVSIQ----FREIQEQHQEMEQLLLSNKIEISHIVDQN--QKNSQYQQNTLY 1801 Query: 1256 ELRVQLSAFESK 1267 Q S F+ + Sbjct: 1802 RSNSQSSDFDRR 1813 Score = 60.9 bits (141), Expect = 3e-07 Identities = 136/707 (19%), Positives = 303/707 (42%), Gaps = 84/707 (11%) Query: 151 IKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXX 210 ++EK+ S L + K ++ I +QE++++K E N+ Sbjct: 1160 VQEKETLNSQLSEQDKQIKVKINQIQEELSKKISSFEELNQ-----------QFVSLEEE 1208 Query: 211 XEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDV-RISSLEEANKLLEAARFEISL 269 + KQQ+ ++E ++ + K ++Q + E K++ R +EE NK EI + Sbjct: 1209 KNNLKQQILSLEEEKQQLDLQTKQKQQ----EFEEKELNREKQIEEINK-----NHEIQM 1259 Query: 270 EHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIE 329 + K+ EL+ L + + K++IEE +L ++ +L K+I+ Sbjct: 1260 Q--KMQTELD-----------SKVVLINAANVQLVQAKSKIEEYKNLYSSHKADLEKQIQ 1306 Query: 330 LLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQL 389 + E KE + KL + S + IS+K+ ++K Q+ Sbjct: 1307 INEEREQSFLNKEKEWKEKL----DQKNLTLSAFYENQSQISQKNEEIQQQRIKQYEQQM 1362 Query: 390 SSETLNQDTD-KKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTL 448 + + D +++ A + + Q +++ E + +++ KD Sbjct: 1363 TQVQSRFENDIQQLQAKHSADISSIEQKFQQEIKQMESKLKQQEILHEQLLKQQ--KD-- 1418 Query: 449 IAQLQLEHQQHMEG-PSLIHVGTN--TEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKL 505 QL+ EH Q ++ S ++ + + + +I ++Q Q+ +N+E K+ K + + Sbjct: 1419 --QLEQEHNQEIQSLQSEVNQKEDKINQSLTQINQLQAQI-DSMNNEKKESTNKIIALEK 1475 Query: 506 KSAE--EQITQLN--DEID-AANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRL 560 +SA+ +++T++ +EI ++ ++K + KL + I+N + + +EI +L Sbjct: 1476 ESAQLKQKLTEIKNPEEIQHQKDEGVLKQQQQQIQKLNEEIILINN--QKNQYEQEIRQL 1533 Query: 561 TEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKM-IEMENLAETRLKAISLL 619 L + + +L++E N Q Y S + E++ + + ++ + + A+S Sbjct: 1534 KLTLQNSIKSANDLDQEISNYQAFRNSYSSQSIHEAESSHSLNVSPTHIPKLNMMALSNR 1593 Query: 620 ESQKF--------------DLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLE 665 E+ +F +L ++ L+ K E+++ L +Q+Q ++ +E+K + LE Sbjct: 1594 ETNEFISPRGPASANSKQIELQLQVKSLENKNKELKESLHQFNQVQ--KINTEMKKL-LE 1650 Query: 666 EQIDALSASKKELALV---IENLKLDKEQLYGTIKDLENDKEDIMNKLQ---NYIQENMD 719 E ++ + EL L E +K + ++L + D E+ +E ++ Q N ++ D Sbjct: 1651 ENRKSIKELETELQLKKSDNEQMKTEIQKLKEALIDFESFEEKLLEMRQIDMNRFEQVRD 1710 Query: 720 LTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRIC 779 D L+++S KI EL +N + + + +D + ++ Y++ IE +++ Sbjct: 1711 KIDDLKEVSQSKI-EL---VNIIQMFALNFKKELDDRNEKIKQYLKKIEKVSIQFREIQE 1766 Query: 780 RLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNR 826 + +E ++ + + DQ Q +Q Q + R Sbjct: 1767 QHQEMEQLLLSNKIEISHIVDQNQKNSQYQQNTLYRSNSQSSDFDRR 1813 >UniRef50_Q13439 Cluster: Golgin subfamily A member 4; n=34; Tetrapoda|Rep: Golgin subfamily A member 4 - Homo sapiens (Human) Length = 2230 Score = 147 bits (356), Expect = 3e-33 Identities = 195/948 (20%), Positives = 409/948 (43%), Gaps = 73/948 (7%) Query: 680 LVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKM----------SA 729 LV + L+KEQL ++ +E K + L + +K+ S Sbjct: 127 LVGNSDSLNKEQLIQRLRRMERSLSSYRGKYSELVTAYQMLQREKKKLQGILSQSQDKSL 186 Query: 730 EKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVME 789 +I+EL ++ ++Q+K Q DA ++E+D YI +++++S K R+ ++ V++ Sbjct: 187 RRIAELREELQMDQQAKKHLQEEFDASLEEKDQYISVLQTQVSLLKQRLRNGPMNVDVLK 246 Query: 790 DRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENK 849 LE +A+ +E ++ E +++ V L L + E L + + Sbjct: 247 PLP-QLEPQAEVFTK--EENPESDGEPVVEDGTSVKTLETLQQRVKRQENLLKRCKETIQ 303 Query: 850 ELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKR 909 +++ +L E + LQ L + Q +EK DL +E TK TQLRD ++ +++ Sbjct: 304 SHKEQCTLLTSEKEALQEQLDERLQE----LEKIK--DLHMAEKTKLITQLRDAKNLIEQ 357 Query: 910 ITHEHQTLIVQKKKEI-EDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYK 968 + + +I + K+++ E LE++ + R K++ + E + A +E + Sbjct: 358 LEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELE 417 Query: 969 NNIENLNMNVEELNKMNLELID--KHVQKQQTQSPDYTEQYINEI-NKLNALLKQKDEEI 1025 + E K+ E+ + K ++K + +Q ++ + ++ ++K+ EE Sbjct: 418 KALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQ 477 Query: 1026 IALNQKINNAQVS--YMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQI 1083 IA QK++ +++ + +++ +F +++ E+ Q ++ K+ E L + Sbjct: 478 IAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQESLAL 537 Query: 1084 ---------LVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXX 1134 ++ E ++++++L++ T+ I + E + S E + + Sbjct: 538 EELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAE 597 Query: 1135 XXXXXXXLKVQEEEEFIQERSVLQEQSA----KLNTELQECYTKIIQL-----ETLNTEL 1185 + V E+ + S+ +Q A KL Q+ T++ +L + T L Sbjct: 598 KNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKETLL 657 Query: 1186 TGHDVVNQEQINQLKSK-LEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLA 1244 +++ Q I ++ K LE+L+ + L S +EL S + A + E++ L Q Sbjct: 658 KDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSEL-SEVLKARHKLEEELSVLKDQ--- 713 Query: 1245 QREADFQKTEHELRVQLSAFESKYEQLLDSV--QSSTQEETNKIVTMEQVTSLQNKLQDK 1302 K + EL ++ ++ ++Q +DS+ + + + +Q+ L+ L+++ Sbjct: 714 -----TDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKER 768 Query: 1303 EEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQM 1362 ++HL+ Q ++ + +I RSE E ++ + + + Q+ Sbjct: 769 DKHLKEHQAHVENL--EADIKRSEGELQQAS--AKLDVFQSYQSATHEQTKAYEEQLAQL 824 Query: 1363 QEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQK--- 1419 Q Q +L++ E L K ++ + +V +L QLE ++SE+ QK Sbjct: 825 Q-QKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKS 883 Query: 1420 -THEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQK 1478 T Y L N E E +Q LVE E I + ++ E+ IL K+ + + + Sbjct: 884 LTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNE 943 Query: 1479 ESEIERVKLIEELNVKITESVSLNKQVAE-LNKALEEEVAKTNEMQTALENQEIEIVTLN 1537 E E + K E+ K+ + K++ E L K L ++ AK ++ LEN +E+ Sbjct: 944 EYE-TKFKNQEKKMEKVKQKA---KEMQETLKKKLLDQEAK---LKKELENTALELSQKE 996 Query: 1538 DEI-TNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAV 1584 + + M +A+S+ I VS ++ + E L +EL D + Sbjct: 997 KQFNAKMLEMAQANSAGISDAVSRLETNQKEQIESLTEVHRRELNDVI 1044 Score = 139 bits (337), Expect = 5e-31 Identities = 267/1403 (19%), Positives = 597/1403 (42%), Gaps = 119/1403 (8%) Query: 215 KQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKL 274 +++ T +++ I +A ++ ++ L+ ++ K + SL + AR ++ E S L Sbjct: 651 QEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVL 710 Query: 275 AQELEQXXXXXXXXXXXXXXLAKQSIEPSCEE-KTEIE--EKGSLEIANMTELTKKIELL 331 + ++ +Q ++ +E + I+ EK + N EL LL Sbjct: 711 KDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLEL-----LL 765 Query: 332 EHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKM-KSPWSQLS 390 + + +++ +EN A + + S K S +S + +K + +QL Sbjct: 766 KERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQ 825 Query: 391 SETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIA 450 + L+ +T++ + ++A++E + + +L + I +D + + + Sbjct: 826 QKLLDLETERILLTKQVAEVEAQKKDVCTEL--DAHKIQVQDLMQQLEKQNSEMEQKVKS 883 Query: 451 QLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEE 510 Q+ + +G E +I +E + ++ + K ++ L +KL + E+ Sbjct: 884 LTQVYESKLEDG------NKEQEQTKQILVEKENMILQMREGQKK-EIEILTQKLSAKED 936 Query: 511 QITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQK 570 I LN+E + KN K K K K+MQ+T+ K+ D +L +EL + + + Sbjct: 937 SIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKK--KLLDQE---AKLKKELENTALE 991 Query: 571 VAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQEL 630 +++ E++ L + +S + SD ++ E + +++ SL E + +L + Sbjct: 992 LSQKEKQFNAKMLEMAQANSAGI--SDAVSRL---ETNQKEQIE--SLTEVHRRELNDVI 1044 Query: 631 HILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKE 690 I ++K ++ ++L +I ++Q + E+ L+++I K+E+ I LK + Sbjct: 1045 SIWEKKLNQQAEELQEIHEIQLQEKEQEV--AELKQKILLFGCEKEEMNKEITWLKEEGV 1102 Query: 691 QLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQ 750 + T+ +L+ + + + Q+ L LEK+ + L +EQ Sbjct: 1103 KQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKM 1162 Query: 751 FGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQ--- 807 + K + +L +++ +++S E+S +ED+ ++ +++L L Sbjct: 1163 LAEEDKRKVSEL-TSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLSEELAIQLDICC 1221 Query: 808 EKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQI 867 +K +A E + +EL+N + + ++ +H ++ K +L++ Sbjct: 1222 KKTEALLE--AKTNELIN---ISSSKTNAILSRISHCQHRTTKV--KEALLIKT-----C 1269 Query: 868 SLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIED 927 ++S+++ L E+ N +++ ++T QL + E+ +K + + ++L+ +K E Sbjct: 1270 TVSELEAQLRQLTEEQNTLNISFQQATH---QLEEKENQIKSMKADIESLVTEK----EA 1322 Query: 928 LEIEFNTQIESAIRDKKV---LNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKM 984 L+ E Q ++A + L ++ +NI VT ++ +L+E K I +L+ + +LN Sbjct: 1323 LQKEGGNQQQAASEKESCITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQ 1382 Query: 985 NLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVS 1044 I + +++ +QY E +L ++ ++ L+++ ++S + V Sbjct: 1383 LQNSIS--LSEKEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLSKE----KISALEQVD 1436 Query: 1045 DYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQIL-VREQDDQIKELKETKLTFE 1103 D+ +K +++ K ++ + Q K+L Q EL+ E+D+QI LKE Sbjct: 1437 DWSNKFSEWKKKAQSRFTQHQNTVKEL----QIQLELKSKEAYEKDEQINLLKEELDQQN 1492 Query: 1104 MNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAK 1163 +G + + M +N++ ++ E E+ I ++++ E Sbjct: 1493 KRFDCLKGEMEDDKSK-MEKKESNLETELKSQTA-----RIMELEDHITQKTIEIES--- 1543 Query: 1164 LNTELQEC-YTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRS 1222 LN L+ K I+ + L +L + +E+ N++K E++ T + + S AEL + Sbjct: 1544 LNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELET 1603 Query: 1223 S------ISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQ 1276 ++ +V + E+ L + ++ A + + + +++A + +QLL ++ Sbjct: 1604 KKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIK---KQLLSQME 1660 Query: 1277 SSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADV-INQIEILRSEIEDEKV-AF 1334 +EE K T ++ L KLQ++E + L+EK V +Q E L + V A+ Sbjct: 1661 E--KEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVAAY 1718 Query: 1335 XXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSIL-NINEENAQLKKSSXXXXXXXXXXXX 1393 + + +++ +L + +E + S Sbjct: 1719 TEQEEADSQGCVQKTYEEKISVLQRNLTEKEKLLQRVGQEKEETVSSHFEMRCQYQERLI 1778 Query: 1394 RVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDE----------------FENV 1437 ++ AEAK E + E+ +K +Y++ + Q ++ F++V Sbjct: 1779 KLEHAEAKQHEDQSMIGHLQEELEEKNKKYSLIVAQHVEKEGGKNNIQAKQNLENVFDDV 1838 Query: 1438 RQQLVE-------YEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEE 1490 ++ L E E++I++L + + R++M E + YE +Q +++ E Sbjct: 1839 QKTLQEKELTCQILEQKIKELDSCLVRQKEVHRVEMEELTSKYEKLQALQQMDGRNKPTE 1898 Query: 1491 LNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRAS 1550 L + TE S + V K L A+ N+++ L E E L EI LQ +R Sbjct: 1899 LLEENTEEKSKSHLVQP--KLLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRML 1956 Query: 1551 SSKIQKHVS-FASDTKQGRDEQL 1572 + Q+ + + Q R+E++ Sbjct: 1957 RKEHQQELEILKKEYDQEREEKI 1979 Score = 132 bits (319), Expect = 8e-29 Identities = 217/1121 (19%), Positives = 473/1121 (42%), Gaps = 88/1121 (7%) Query: 487 QELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDN 546 ++L +N + LI++L+ E ++ + ++ + +++ ++ +K Sbjct: 125 EDLVGNSDSLNKEQLIQRLRRMERSLSSYRGKYS-------ELVTAYQMLQREKKKLQGI 177 Query: 547 FSKVSDSN-KEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEM 605 S+ D + + I L EEL Q L+EE Y S + + K+ + Sbjct: 178 LSQSQDKSLRRIAELREELQMDQQAKKHLQEEFDASLEEKDQYISVLQTQVSLLKQRLRN 237 Query: 606 ENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLE 665 + LK + LE Q +E + VED + + L++ Q + + L+ Sbjct: 238 GPMNVDVLKPLPQLEPQAEVFTKEENPESDGEPVVEDGTS-VKTLETLQQRVKRQENLLK 296 Query: 666 EQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIM---NKLQNYIQENMDLTD 722 + + + K++ L+ + +EQL +++LE K+ M KL +++ +L + Sbjct: 297 RCKETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIE 356 Query: 723 KLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSK-YKSRICRL 781 +LE+ I+E +++ + K + + ++I++ E + + K ++ L Sbjct: 357 QLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEEL 416 Query: 782 EESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRL--AVLMDHDRVVEK 839 E++++ + + + ++ ++ +K E I + ++R+ V+ + E+ Sbjct: 417 EKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEE 476 Query: 840 QLLEIE--HENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQ 897 Q+ +++ HE KEL +K Q E + LQ + Q+ +EK+ L S+ + Q Sbjct: 477 QIAKLQKLHE-KELARKEQ---ELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQ 532 Query: 898 TQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYV 957 L L+ + + + ++ + + ++ DL+ E T + + L + ++N Sbjct: 533 ESLA-----LEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQS 587 Query: 958 TQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPD-YTEQYINEINKLNA 1016 L L+ KN + E +K LE + T+ +QY E+ KL Sbjct: 588 KDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLRE 647 Query: 1017 LLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQ 1076 +Q+ E ++ + I A + M+ KL T+LE++ E+ V K + Sbjct: 648 KCEQEKETLLKDKEIIFQAHIEEMN--EKTLEKLDVKQTELESLSSELSEVLKA---RHK 702 Query: 1077 HNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXX 1136 EEL +L ++Q D++K+ E K+ + N + + + S I+ + Sbjct: 703 LEEELSVL-KDQTDKMKQELEAKMDEQKNHHQQQ---VDSIIKEHEVSIQRTEKALKDQI 758 Query: 1137 XXXXXLKVQEEEEFIQERSV----LQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVN 1192 L ++E ++ ++E L+ + ELQ+ K+ ++ + Sbjct: 759 NQLELL-LKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAY 817 Query: 1193 QEQINQLKSKLEQLNTENDNLLSTVAEL---RSSISSAVDQRGFEIAELWKQHLAQREAD 1249 +EQ+ QL+ KL L TE L VAE+ + + + +D ++ +L +Q Sbjct: 818 EEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQ-------- 869 Query: 1250 FQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNL 1309 +K E+ ++ + YE L+ + QE+T +I+ ++ LQ + K+E + L Sbjct: 870 LEKQNSEMEQKVKSLTQVYESKLED-GNKEQEQTKQILVEKENMILQMREGQKKE-IEIL 927 Query: 1310 QEKYADVINQIEILRSEIE----DEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQ 1365 +K + + I IL E E +++ L + K+ E Sbjct: 928 TQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELEN 987 Query: 1366 SILNINEE----NAQLKKSSXXXXXXXXXXXXRVNDAEAKVLE-LT--HQLELKD----- 1413 + L ++++ NA++ + + R+ + + +E LT H+ EL D Sbjct: 988 TALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQKEQIESLTEVHRRELNDVISIW 1047 Query: 1414 -SEIYQKTHE----YTITLTQRNDEFENVRQQLV----EYEKRIEDLTYEKE------SE 1458 ++ Q+ E + I L ++ E ++Q+++ E E+ +++T+ KE + Sbjct: 1048 EKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTT 1107 Query: 1459 LAILRLKMHENANHYETM-QKESEIER--VKLIEELNVKITESVSLNKQVAELNKALEEE 1515 L L+ ++ + + H ++ Q E++++ KL +LN + E+ L +Q+ EL EE+ Sbjct: 1108 LNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEED 1167 Query: 1516 VAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQK 1556 K +E+ + L+ + E +L + S + +K Sbjct: 1168 KRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKK 1208 Score = 128 bits (310), Expect = 9e-28 Identities = 258/1473 (17%), Positives = 618/1473 (41%), Gaps = 139/1473 (9%) Query: 150 TIKEKDNALSVLQVKMKIMETTI------LDLQEKINEKDQIIEAKNKATTXXXXXXXXX 203 +++EKD +SVLQ ++ +++ + +D+ + + + + E K Sbjct: 213 SLEEKDQYISVLQTQVSLLKQRLRNGPMNVDVLKPLPQLEPQAEVFTKEENPESDGEPVV 272 Query: 204 XXXXXXXXEDTKQQMTKMQENFIAMEAEW-KDEKQRLLKDIESKDVRISSLEEANKLLEA 262 +T QQ K QEN + E + K++ K+ L+E + LE Sbjct: 273 EDGTSVKTLETLQQRVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQELEK 332 Query: 263 ARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMT 322 + E +KL +L AK IE + E ++KG + Sbjct: 333 IKDLHMAEKTKLITQLRD---------------AKNLIE-----QLE-QDKGMVIAETKR 371 Query: 323 ELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKM 382 ++ + +E+ E Q+R K++ T G E + S++ + + +TA K Sbjct: 372 QMHETLEMKEEEIAQLRSRIKQM----TTQGEELREQKEKSERAA-FEELEKALSTAQKT 426 Query: 383 KSPWSQLSSETLNQ-DTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXX 441 + +L +E Q T +K ++ E L+ + + +++VD SE+ Sbjct: 427 EEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQ--------- 477 Query: 442 XXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDL 501 IA+LQ H++ + E+ K + ++E +++K K Sbjct: 478 -------IAKLQKLHEKEL-----------ARKEQELTKKLQTREREFQEQMKVALEKSQ 519 Query: 502 IEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNF-SKVSDSNKEIVRL 560 E LK ++E+ Q + ++ + + + KL+ +Q+ + + +++ + + + Sbjct: 520 SEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKS 579 Query: 561 TEELHHLSQKVA---ELEEEKGNLQL------HLVDYDSGRMIESDVYKKMIE-MENLAE 610 +E + S+ +A E E+ K N ++ H + +S + + ++ + ++ ++ + Sbjct: 580 LQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQ 639 Query: 611 TRLKAI-SLLESQKFDLVQELHILQQKY-DEVEDKLADISQLQSDQVCSEIKSVHLEEQI 668 T ++ + E +K L+++ I+ Q + +E+ +K + +L Q E S L E + Sbjct: 640 TEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKT--LEKLDVKQTELESLSSELSEVL 697 Query: 669 DALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMS 728 A ++EL+++ + K++L + + +N + ++ + + ++ T+K K Sbjct: 698 KARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQ 757 Query: 729 AEKISELLAKINHEEQSKIQTQF-GIDAKIQERDLYIENIESELSKYKSRICRLEESIAV 787 ++ ELL K + + Q ++A I+ + ++ ++L ++S E Sbjct: 758 INQL-ELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKA 816 Query: 788 MEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHE 847 E++ L++K L + K +E Q+ ++ L H V+ + ++E + Sbjct: 817 YEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDA---HKIQVQDLMQQLEKQ 873 Query: 848 NKELQKKNQILLEENQN-LQISLSDMQQHYNALVEKANRT-DLAESESTKYQTQLRDL-- 903 N E+++K + L + ++ L+ + +Q LVEK N + E + + + + L Sbjct: 874 NSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSA 933 Query: 904 -ESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNE--KYEKNIEYVTQL 960 E ++ + E++T ++K++E ++ + E+ KK+L++ K +K +E T L Sbjct: 934 KEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETL--KKKLLDQEAKLKKELEN-TAL 990 Query: 961 EAQLQEYKNNIENLNMNVEELNKMNL-ELIDKHVQKQQTQSPDYTEQYINEINKLNALLK 1019 E +E + N + L M + N + + + + Q+ Q TE + E+N + ++ + Sbjct: 991 ELSQKEKQFNAKMLEM--AQANSAGISDAVSRLETNQKEQIESLTEVHRRELNDVISIWE 1048 Query: 1020 QKDEEIIALNQKINNAQVSYMSM-VSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHN 1078 +K + Q+I+ Q+ V++ + K+ F + E M +E+ + ++ + Sbjct: 1049 KKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTL 1108 Query: 1079 EELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXX 1138 ELQ ++++ + L + + + ++ K E + S E V+ Sbjct: 1109 NELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDK 1168 Query: 1139 XXXLKVQEEEEFIQER-SVLQEQSAKLNTELQECYTKIIQLETLNTELTGH-DVVNQEQI 1196 ++ + + E L+ K N L++ K ++ + L+ EL D+ ++ Sbjct: 1169 RKVSELTSKLKTTDEEFQSLKSSHEKSNKSLED---KSLEFKKLSEELAIQLDICCKKTE 1225 Query: 1197 NQLKSKLEQL----NTENDNLLSTVAELR---SSISSAVDQRGFEIAELWKQ--HLAQRE 1247 L++K +L +++ + +LS ++ + + + A+ + ++EL Q L + + Sbjct: 1226 ALLEAKTNELINISSSKTNAILSRISHCQHRTTKVKEALLIKTCTVSELEAQLRQLTEEQ 1285 Query: 1248 ADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLR 1307 + + QL E++ + + ++S T K ++ + Q +KE + Sbjct: 1286 NTLNISFQQATHQLEEKENQIKSMKADIESLV---TEKEALQKEGGNQQQAASEKESCIT 1342 Query: 1308 NLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSI 1367 L+++ ++ IN + +++ E++++KV +++ +N +E +I Sbjct: 1343 QLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDL------NVQLQNSISLSEKEAAI 1396 Query: 1368 LNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITL 1427 ++ ++ + K ++ + LE K SE +K Sbjct: 1397 SSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQS---RF 1453 Query: 1428 TQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKL 1487 TQ + + ++ QL K YEK+ ++ +L+ ++ + ++ ++ E E ++ K+ Sbjct: 1454 TQHQNTVKELQIQLELKSKE----AYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKM 1509 Query: 1488 IEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMV 1547 K+ + L L+ + A+ E++ + + IEI +LN+ + N Sbjct: 1510 --------------EKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQK 1555 Query: 1548 RASSSKIQKHVSFASDTKQGRDEQLDNTMNKEL 1580 ++ + + + + +D ++ K L Sbjct: 1556 DIEHKELVQKLQHFQELGEEKDNRVKEAEEKIL 1588 Score = 113 bits (271), Expect = 5e-23 Identities = 172/874 (19%), Positives = 392/874 (44%), Gaps = 76/874 (8%) Query: 246 KDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCE 305 K +S LE + L + +++ + +LE+ L + E + Sbjct: 1267 KTCTVSELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLVTEK-EALQK 1325 Query: 306 EKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKK 365 E ++ S + + +T+L K EL E++N + +EL+ K + + SK ++ + + Sbjct: 1326 EGGNQQQAASEKESCITQLKK--ELSENINA-VTLMKEELKEKKVEISSLSKQLTDLNVQ 1382 Query: 366 GSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKE 425 IS S ++ + + E L+Q D + ++K E + D + Sbjct: 1383 LQNSISLSEKEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLSK-EKISALEQVDDWSNK 1441 Query: 426 YVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQL 485 + +K K+ I QL+L+ ++ E I++ E++++ K + L Sbjct: 1442 FSEWKKKAQSRFTQHQNTVKELQI-QLELKSKEAYEKDEQINL--LKEELDQQNKRFDCL 1498 Query: 486 KQELNDEIKDVNVKD--LIEKLKSA-------EEQITQLNDEIDAANKNMIKVKSNHKLK 536 K E+ D+ + K+ L +LKS E+ ITQ EI++ N+ + ++ Sbjct: 1499 KGEMEDDKSKMEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIE 1558 Query: 537 LKQMQKTIDNFSKVSDSNKEIVRLTEE-LHHLSQKV----AELEEEKGNLQLHLVDYDSG 591 K++ + + +F ++ + V+ EE + L +V AELE +K L+ H+ Sbjct: 1559 HKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELE-HVNLSVKS 1617 Query: 592 RMIESDVYKKMIEMEN---LAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADIS 648 + E + +E E+ LAE + KA + + K L+ ++ +++Y + + + +S Sbjct: 1618 KEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTE--SHLS 1675 Query: 649 QLQSDQVCSEIKSVH-LEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIM 707 +L + ++ + VH LEE++ ++ +S+ E +V + K E ++ D Sbjct: 1676 ELNT-KLQEREREVHILEEKLKSVESSQSETLIVPRSAK-------NVAAYTEQEEADSQ 1727 Query: 708 NKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENI 767 +Q +E + + L++ EK +LL ++ E++ + + F + + QER + +E+ Sbjct: 1728 GCVQKTYEEKISV---LQRNLTEK-EKLLQRVGQEKEETVSSHFEMRCQYQERLIKLEHA 1783 Query: 768 ESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRL 827 E++ + +S I L+E + ++++YSL Q +K + IQ + N Sbjct: 1784 EAKQHEDQSMIGHLQEELE-EKNKKYSL--------IVAQHVEKEGGKNNIQAKQ--NLE 1832 Query: 828 AVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTD 887 V D + ++++ L + +++++ + L+ + + ++ + ++ Y L Sbjct: 1833 NVFDDVQKTLQEKELTCQILEQKIKELDSCLVRQKEVHRVEMEELTSKYEKL------QA 1886 Query: 888 LAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLN 947 L + + T+L + + K +H Q ++ E + ++EF ++ A R+K+ L Sbjct: 1887 LQQMDGRNKPTELLEENTEEKSKSHLVQPKLL-SNMEAQHNDLEF--KLAGAEREKQKLG 1943 Query: 948 EKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQY 1007 ++ + L +E++ +E L ++ E +K Q+Q+ + Sbjct: 1944 KEI---VRLQKDLRMLRKEHQQELEILKKEYDQ------EREEKIKQEQEDLELKHNSTL 1994 Query: 1008 INEINKLNALLKQKDEEI-IALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQR 1066 + + N L QK++E+ + + + IN AQ ++ ++ + Q K+ +++++R Sbjct: 1995 KQLMREFNTQLAQKEQELEMTIKETINKAQEVEAELLESHQEETNQLLKKIAEKDDDLKR 2054 Query: 1067 VSK---QLLDSKQHNEELQILVREQDDQIKELKE 1097 +K ++LD+++ EE+ VR+ Q++EL++ Sbjct: 2055 TAKRYEEILDARE--EEMTAKVRDLQTQLEELQK 2086 Score = 46.0 bits (104), Expect = 0.009 Identities = 109/596 (18%), Positives = 243/596 (40%), Gaps = 65/596 (10%) Query: 146 HLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXX 205 H +EKDN + + K+ +E + ++ ++ K + +E N + Sbjct: 1568 HFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALED 1627 Query: 206 XXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRI-----SSLEEANKLL 260 ++ + E IA K++LL +E K+ + S L E N L Sbjct: 1628 RLESESAAKLAELKRKAEQKIAA------IKKQLLSQMEEKEEQYKKGTESHLSELNTKL 1681 Query: 261 EAARFEISLEHSKL----AQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSL 316 + E+ + KL + + E +++ C +KT EEK S+ Sbjct: 1682 QEREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQEEADSQGCVQKT-YEEKISV 1740 Query: 317 EIANMTELTKKIE---------LLEH--LNCQIRQTNKELENKLA-------TMGTESKA 358 N+TE K ++ + H + CQ ++ +LE+ A +G + Sbjct: 1741 LQRNLTEKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKLEHAEAKQHEDQSMIGHLQEE 1800 Query: 359 VSSPSKKGSPLIS----RKSGRN---TASKMKSPWSQLSSETLNQDTDKKINKNEIAKLE 411 + +KK S +++ ++ G+N +++ + + ++ +I + +I +L+ Sbjct: 1801 LEEKNKKYSLIVAQHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELTCQILEQKIKELD 1860 Query: 412 -MVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEH--QQHMEGPSLI-H 467 +++ V+ E + S+ + K T + + E + H+ P L+ + Sbjct: 1861 SCLVRQKEVHRVEMEELTSKYEKLQALQQMDGRNKPTELLEENTEEKSKSHLVQPKLLSN 1920 Query: 468 VGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMI 527 + D+ E+ KQ+L EI + KDL K ++++ L E D + I Sbjct: 1921 MEAQHNDLEFKLAGAEREKQKLGKEIVRLQ-KDLRMLRKEHQQELEILKKEYDQEREEKI 1979 Query: 528 KVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELH-HLSQKVAELEEEKGNLQLHLV 586 K + L+LK T+ + + N ++ + +EL + + + + +E + L Sbjct: 1980 K-QEQEDLELKH-NSTLKQLMR--EFNTQLAQKEQELEMTIKETINKAQEVEAEL----- 2030 Query: 587 DYDSGRMIESDVYKKMIEM-ENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLA 645 +S + + + KK+ E ++L T + +L++++ ++ ++ LQ + +E++ K Sbjct: 2031 -LESHQEETNQLLKKIAEKDDDLKRTAKRYEEILDAREEEMTAKVRDLQTQLEELQKKYQ 2089 Query: 646 DISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLEN 701 + + + + + L+ Q+ A K L I + KL +++ I +LE+ Sbjct: 2090 QKLEQEENPGNDNVTIMELQTQL----AQKTTL---ISDSKLKEQEFREQIHNLED 2138 >UniRef50_Q25893 Cluster: Liver stage antigen; n=41; Plasmodium falciparum|Rep: Liver stage antigen - Plasmodium falciparum Length = 1909 Score = 146 bits (354), Expect = 4e-33 Identities = 287/1455 (19%), Positives = 631/1455 (43%), Gaps = 113/1455 (7%) Query: 151 IKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXX 210 ++E+ + L ++ + ++ DL+++ K+++ E ++ Sbjct: 192 LQEQQSDLEQERLAKEKLQEQQSDLEQERLAKEKLQEQQSDLEQERRAKEKLQEQQSDLE 251 Query: 211 XEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLE 270 E ++ + Q++ + E K++ Q D+E + + L+E LE R + Sbjct: 252 QERRAKEKLQEQQSDLEQERRAKEKLQEQQSDLEQERLAKEKLQEQQSDLEQER-RAKEK 310 Query: 271 HSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIEL 330 + +LEQ L ++ + +EK + E++ LE + + +K++ Sbjct: 311 LQEQQSDLEQERLAKEKLQEQQSDLEQERL---AKEKLQ-EQQSDLEQERLAK--EKLQG 364 Query: 331 LEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQ-- 388 + Q R ++L+ + + + + A ++ S L + + + +S Q Sbjct: 365 QQSDLEQERLAKEKLQEQQSDLEQDRLAKEKLQEQQSDLEQERLAKEKLQEQQSDLEQER 424 Query: 389 LSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTL 448 + E L Q+ + + +AK + +Q DL + + K+ L Sbjct: 425 RAKEKL-QEQQSDLEQERLAKEK--LQEQQSDLEQERRAKEKLQEQQSDLEQERRAKEKL 481 Query: 449 IAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSA 508 Q Q+ + L ++ E +AK E+L+++ +D ++ K+ +++ +S Sbjct: 482 QEQQSDLEQERLAKEKLQEQQSDLEQ-ERLAK--EKLQEQQSDSEQERLAKEKLQEQQSD 538 Query: 509 EEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLS 568 EQ +++ + ++ + K KL++ Q SD +E RL +E L Sbjct: 539 LEQERLAKEKLQEQQSD-LEQERLAKEKLQEQQ---------SDLEQE--RLAKE--KLQ 584 Query: 569 QKVAELEEE---KGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFD 625 ++ ++LE+E K LQ D + R+ + K + +L + RL A L+ Q+ D Sbjct: 585 EQQSDLEQERLAKEKLQGQQSDLEQERLAKE---KLQGQQSDLEQERL-AKEKLQEQQSD 640 Query: 626 LVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASK-KELALVIEN 684 L QE + ++K ++++ +D+ + ++ + + + LE+ + L+ K +E +E Sbjct: 641 LEQE-RLAKEK---LQEQQSDLERTKASKETLQEQQSDLEQ--ERLAKEKLQEQQSDLEQ 694 Query: 685 LKLDKEQLYGTIKDLENDK--EDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKIN-H 741 + KE+L DLE ++ ++ + + Q+ +++ +KL++ ++ E AK Sbjct: 695 ERRAKEKLQEQQSDLEQERRAKEKLQEQQSDLEQERRAKEKLQEQQSDLEQERRAKEKLQ 754 Query: 742 EEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQ 801 E+QS ++ K+QE+ +S+L + + +L+E + +E R + E+ +Q Sbjct: 755 EQQSDLEQDRLAKEKLQEQ-------QSDLEQERRAKEKLQEQQSDLEQDRLAKEKLQEQ 807 Query: 802 LGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQL-LEIEHENKELQKKNQILLE 860 QE++ Q D RLA +++ E+Q LE E KE ++ Q LE Sbjct: 808 QSDLEQERRAKEKLQEQQSDLEQERLA----KEKLQEQQSDLEQERRAKEKLQEQQSDLE 863 Query: 861 EN----QNLQISLSDMQQHYNA---LVEKANRTDLAESESTKYQTQLRDLESN--LKRIT 911 ++ + LQ SD++Q A L E+ + + K Q Q DLE K Sbjct: 864 QDRLAKEKLQEQQSDLEQERRAKEKLQEQQSDLEQERRAKEKLQEQQSDLEQERLAKEKL 923 Query: 912 HEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNI 971 E Q + Q+++ E L+ E + +E R K+ L E+ + ++E + +LQE ++++ Sbjct: 924 QEQQRDLEQERRAKEKLQ-EQQSDLEQERRAKEKLQEQ-QSDLEQERLAKEKLQEQQSDL 981 Query: 972 ENLNMNVEELNKMNLELIDKHVQKQ--QTQSPDYTEQYINEINKLNALLKQKDEEIIALN 1029 E + E+L + +L + + K+ Q Q D ++ + + KL ++E +A Sbjct: 982 EQERLAKEKLQEQQSDLEQERLAKEKLQGQQSDLEQERLAK-EKLQGQQSDLEQERLA-K 1039 Query: 1030 QKINNAQVSYMSMVSDYE-SKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQ 1088 +K+ Q SD E +LA+ + + + E +R++K+ L +Q + E + L +E+ Sbjct: 1040 EKLQEQQ-------SDLEQERLAKEKLQEQQSDLEQERLAKEKLQGQQSDLEQERLAKEK 1092 Query: 1089 -DDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEE 1147 Q +L++ +L E K +G E ++ + K+QE+ Sbjct: 1093 LQGQQSDLEQERLAKE----KLQGQQSDLEQERLAKEKLQGQQSDLEQERLAKE-KLQEQ 1147 Query: 1148 EEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLN 1207 + +++ + +E+ + ++L++ +L+ ++L ++E + + +S LEQ Sbjct: 1148 QSDLEQERLAKEKLQEQQSDLEQERRAKEKLQEQQSDLE-RTKASKETLQEQQSDLEQER 1206 Query: 1208 TENDNLLSTVAEL----RSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSA 1263 + L ++L R+ Q E L K+ L ++++D ++ E + +L Sbjct: 1207 LAKEKLQEQQSDLEQERRAKEKLQEQQSDLEQERLAKEKLQEQQSDLEQ-ERRAKEKLQE 1265 Query: 1264 FESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEIL 1323 +S EQ + + +++++ +EQ + KLQ+++ L QE+ A +++ Sbjct: 1266 QQSDLEQERRAKEKLQEQQSD----LEQERRAKEKLQEQQSDLE--QERLAK--EKLQEQ 1317 Query: 1324 RSEIEDEKVA-FXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSX 1382 +S++E E++A + E QS + + + + E+ + L++ Sbjct: 1318 QSDLEQERLAKEKLQEQQSDLEQERRAKEKLQEQQSDLEQERLAKEKLQEQQSDLEQERR 1377 Query: 1383 XXXXXXXXXXXRVND--AEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQ 1440 D A+ K+ E LE ++ +K E L Q E +++Q Sbjct: 1378 AKEKLQEQQSDLEQDRLAKEKLQEQQRDLE-QERRAKEKLQEQQSDLEQERRAKEKLQEQ 1436 Query: 1441 L--VEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITES 1498 +E E+R ++ E++S+L R + E ++ ++ + + KL +E + + Sbjct: 1437 QSDLEQERRAKEKLQEQQSDLEQER-RAKEKLQEQQSDLEQERLAKEKL-QEQQRDLEQE 1494 Query: 1499 VSLNKQVAELNKALEEE---VAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQ 1555 +++ E LE+E K E Q+ LE + + L ++ +L+ RA K+Q Sbjct: 1495 RRAKEKLQEQQSDLEQERRAKEKLQEQQSDLEQERLANEKLQEQQRDLEQERRA-KEKLQ 1553 Query: 1556 KHVSFASDTKQGRDE 1570 + S ++ +++ Sbjct: 1554 EQQSDLEQERRAKEK 1568 Score = 135 bits (326), Expect = 1e-29 Identities = 258/1253 (20%), Positives = 542/1253 (43%), Gaps = 101/1253 (8%) Query: 402 INKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTL-----------IA 450 + +N++ K +I+ + D DK+ I +D K+TL +A Sbjct: 112 LKENKLNKEGKLIEHIINDDDDKKKYIKGQDENRQEDLEEKAAKETLQGQQSDLEQERLA 171 Query: 451 QLQLEHQQ---HMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKS 507 + +L+ QQ E + + D+ + +E+L+++ +D ++ K+ +++ +S Sbjct: 172 KEKLQEQQSDSEQERLAKEKLQEQQSDLEQERLAKEKLQEQQSDLEQERLAKEKLQEQQS 231 Query: 508 AEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSD------SNKEIVRLT 561 EQ + +++ + ++ + K KL++ Q ++ + + S+ E RL Sbjct: 232 DLEQERRAKEKLQEQQSD-LEQERRAKEKLQEQQSDLEQERRAKEKLQEQQSDLEQERLA 290 Query: 562 EELHHLSQKVAELEEE---KGNLQLHLVDYDSGRMIESDVYKKM--IEMENLAETRLK-- 614 +E L ++ ++LE+E K LQ D + R+ + + ++ +E E LA+ +L+ Sbjct: 291 KE--KLQEQQSDLEQERRAKEKLQEQQSDLEQERLAKEKLQEQQSDLEQERLAKEKLQEQ 348 Query: 615 ---------AISLLESQKFDLVQEL----HILQQKYDEVEDKLA--DISQLQSDQVCSEI 659 A L+ Q+ DL QE + +Q+ D +D+LA + + QSD + Sbjct: 349 QSDLEQERLAKEKLQGQQSDLEQERLAKEKLQEQQSDLEQDRLAKEKLQEQQSDLEQERL 408 Query: 660 KSVHLEEQIDALSASKK------ELALVIENLKLDKEQLYGTIKDLENDK--EDIMNKLQ 711 L+EQ L ++ E +E +L KE+L DLE ++ ++ + + Q Sbjct: 409 AKEKLQEQQSDLEQERRAKEKLQEQQSDLEQERLAKEKLQEQQSDLEQERRAKEKLQEQQ 468 Query: 712 NYIQENMDLTDKLEKMSAEKISELLAKIN-HEEQSKIQTQFGIDAKIQERDLYIENIESE 770 + +++ +KL++ ++ E LAK E+QS ++ + K+QE+ E Sbjct: 469 SDLEQERRAKEKLQEQQSDLEQERLAKEKLQEQQSDLEQERLAKEKLQEQQSDSEQERLA 528 Query: 771 LSKYKSRICRLE-ESIAVMEDRRYSLERKADQLG-SYLQEKQKAYSEYTIQEDELVNRLA 828 K + + LE E +A + + + + ++L LQE+Q + + +++L + + Sbjct: 529 KEKLQEQQSDLEQERLAKEKLQEQQSDLEQERLAKEKLQEQQSDLEQERLAKEKLQEQQS 588 Query: 829 VLMDHDRVVEKQL------LEIEHENKELQKKNQILLEE----NQNLQISLSDMQQHYNA 878 L + +R+ +++L LE E KE + Q LE+ + LQ SD++Q A Sbjct: 589 DL-EQERLAKEKLQGQQSDLEQERLAKEKLQGQQSDLEQERLAKEKLQEQQSDLEQERLA 647 Query: 879 LVE-KANRTDLAESESTK--YQTQLRDLESN--LKRITHEHQTLIVQKKKEIEDLEIEFN 933 + + ++DL ++++K Q Q DLE K E Q+ + Q+++ E L+ E Sbjct: 648 KEKLQEQQSDLERTKASKETLQEQQSDLEQERLAKEKLQEQQSDLEQERRAKEKLQ-EQQ 706 Query: 934 TQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHV 993 + +E R K+ L E+ + ++E + + +LQE ++++E E+L + +L + Sbjct: 707 SDLEQERRAKEKLQEQ-QSDLEQERRAKEKLQEQQSDLEQERRAKEKLQEQQSDLEQDRL 765 Query: 994 QKQQTQSPDY-TEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQ 1052 K++ Q EQ KL +Q D E L ++ Q S + + KL + Sbjct: 766 AKEKLQEQQSDLEQERRAKEKLQE--QQSDLEQDRLAKEKLQEQQSDLEQERRAKEKLQE 823 Query: 1053 FTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDD-QIKELKETKLTFEMNIPKTEG 1111 + LE +++ +Q D +Q + L +Q D + L + KL + + + E Sbjct: 824 QQSDLEQERLAKEKLQEQQSDLEQERRAKEKLQEQQSDLEQDRLAKEKLQEQQSDLEQER 883 Query: 1112 MIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQEC 1171 E SD + + +E +QE+ EQ + +LQE Sbjct: 884 RAKEKLQEQQSDLEQERRAKEKLQEQQSDLEQERLAKEKLQEQQRDLEQERRAKEKLQEQ 943 Query: 1172 YTKIIQLETLNTELTGHDV-VNQEQINQLKSKLEQLNTENDNLL-STVAELRSSISS--- 1226 + + Q +L + QE++ + K + +Q + E + L + E +S + Sbjct: 944 QSDLEQERRAKEKLQEQQSDLEQERLAKEKLQEQQSDLEQERLAKEKLQEQQSDLEQERL 1003 Query: 1227 AVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEE--TN 1284 A ++ + ++L ++ LA+ + Q + +L + A E EQ D Q +E Sbjct: 1004 AKEKLQGQQSDLEQERLAKEK--LQGQQSDLEQERLAKEKLQEQQSDLEQERLAKEKLQE 1061 Query: 1285 KIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXX 1344 + +EQ + KLQ ++ L QE+ A +++ +S++E E++A Sbjct: 1062 QQSDLEQERLAKEKLQGQQSDLE--QERLAK--EKLQGQQSDLEQERLAKEKLQGQQSDL 1117 Query: 1345 XXXXXXDLRTENQSYKQMQEQ-SILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVL 1403 + + Q QE+ + + E+ + L++ + AK Sbjct: 1118 EQERLAKEKLQGQQSDLEQERLAKEKLQEQQSDLEQERLAKEKLQEQQSDLEQERRAKEK 1177 Query: 1404 ELTHQLELKDSEIYQKT-HEYTITLTQRNDEFENVRQQL--VEYEKRIEDLTYEKESELA 1460 Q +L+ ++ ++T E L Q E +++Q +E E+R ++ E++S+L Sbjct: 1178 LQEQQSDLERTKASKETLQEQQSDLEQERLAKEKLQEQQSDLEQERRAKEKLQEQQSDLE 1237 Query: 1461 ILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEE---VA 1517 RL + +++E + + ++E + + +++ E LE+E Sbjct: 1238 QERLAKEKLQEQQSDLEQERRAK--EKLQEQQSDLEQERRAKEKLQEQQSDLEQERRAKE 1295 Query: 1518 KTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDE 1570 K E Q+ LE + + L ++ ++L+ R + K+Q+ S ++ +++ Sbjct: 1296 KLQEQQSDLEQERLAKEKLQEQQSDLE-QERLAKEKLQEQQSDLEQERRAKEK 1347 Score = 123 bits (296), Expect = 5e-26 Identities = 232/1064 (21%), Positives = 457/1064 (42%), Gaps = 92/1064 (8%) Query: 212 EDTKQQMTKMQENFIAME---AEWKD-EKQRLLKDIESKDVRISSLEEANKLLEAARFEI 267 E ++Q + +++ +A E + D E++RL K E + S LE+ E + + Sbjct: 581 EKLQEQQSDLEQERLAKEKLQGQQSDLEQERLAK--EKLQGQQSDLEQERLAKEKLQEQQ 638 Query: 268 S-LEHSKLAQE-LEQXXXXXXXXXXXXXXLAKQSIEPSCEE--KTEIEEKGSLEIANMTE 323 S LE +LA+E L++ L +Q + E K +++E+ S ++ Sbjct: 639 SDLEQERLAKEKLQEQQSDLERTKASKETLQEQQSDLEQERLAKEKLQEQQS-DLEQERR 697 Query: 324 LTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMK 383 +K++ + Q R+ ++L+ + + + E +A ++ S L + + + + Sbjct: 698 AKEKLQEQQSDLEQERRAKEKLQEQQSDLEQERRAKEKLQEQQSDLEQERRAKEKLQEQQ 757 Query: 384 SPWSQ--LSSETLN-QDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXX 440 S Q L+ E L Q +D + + KL+ L +D + KE + ++ Sbjct: 758 SDLEQDRLAKEKLQEQQSDLEQERRAKEKLQEQQSDLEQDRLAKEKLQEQQSDLEQERRA 817 Query: 441 XXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKD 500 K+ L Q Q+ + L D+ + + +E+L+++ +D +D K+ Sbjct: 818 ----KEKLQEQQSDLEQERLAKEKLQE---QQSDLEQERRAKEKLQEQQSDLEQDRLAKE 870 Query: 501 LIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNF----SKVSDSNKE 556 +++ +S EQ + +++ ++ + + K KL++ Q ++ K+ + ++ Sbjct: 871 KLQEQQSDLEQERRAKEKLQEQQSDL-EQERRAKEKLQEQQSDLEQERLAKEKLQEQQRD 929 Query: 557 IVRLTEELHHLSQKVAELEEE---KGNLQLHLVDYDSGRMIESDVYKKM--IEMENLAET 611 + + L ++ ++LE+E K LQ D + R+ + + ++ +E E LA+ Sbjct: 930 LEQERRAKEKLQEQQSDLEQERRAKEKLQEQQSDLEQERLAKEKLQEQQSDLEQERLAKE 989 Query: 612 RLK-----------AISLLESQKFDLVQEL----HILQQKYDEVEDKLAD--ISQLQSDQ 654 +L+ A L+ Q+ DL QE + Q+ D +++LA + + QSD Sbjct: 990 KLQEQQSDLEQERLAKEKLQGQQSDLEQERLAKEKLQGQQSDLEQERLAKEKLQEQQSDL 1049 Query: 655 VCSEIKSVHLEEQIDALSA---SKKELA---LVIENLKLDKEQLYGTIKDLEND---KED 705 + L+EQ L +K++L +E +L KE+L G DLE + KE Sbjct: 1050 EQERLAKEKLQEQQSDLEQERLAKEKLQGQQSDLEQERLAKEKLQGQQSDLEQERLAKEK 1109 Query: 706 IMNKLQNYIQENMDLTDKLEKMSAEKISELLAKIN-HEEQSKIQTQFGIDAKIQER--DL 762 + + + QE + +KL+ ++ E LAK E+QS ++ + K+QE+ DL Sbjct: 1110 LQGQQSDLEQERL-AKEKLQGQQSDLEQERLAKEKLQEQQSDLEQERLAKEKLQEQQSDL 1168 Query: 763 Y--------IENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYS 814 ++ +S+L + K+ L+E + +E R + E+ +Q QE++ Sbjct: 1169 EQERRAKEKLQEQQSDLERTKASKETLQEQQSDLEQERLAKEKLQEQQSDLEQERRAKEK 1228 Query: 815 EYTIQEDELVNRLAVLMDHDRVVEKQL-LEIEHENKELQKKNQILLEE----NQNLQISL 869 Q D RLA +++ E+Q LE E KE ++ Q LE+ + LQ Sbjct: 1229 LQEQQSDLEQERLA----KEKLQEQQSDLEQERRAKEKLQEQQSDLEQERRAKEKLQEQQ 1284 Query: 870 SDMQQHYNA---LVEKANRTDLAESESTKYQTQLRDLESN--LKRITHEHQTLIVQKKKE 924 SD++Q A L E+ + + K Q Q DLE K E Q+ + Q+++ Sbjct: 1285 SDLEQERRAKEKLQEQQSDLEQERLAKEKLQEQQSDLEQERLAKEKLQEQQSDLEQERRA 1344 Query: 925 IEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKM 984 E L+ E + +E K+ L E+ + ++E + + +LQE ++++E + E+L + Sbjct: 1345 KEKLQ-EQQSDLEQERLAKEKLQEQ-QSDLEQERRAKEKLQEQQSDLEQDRLAKEKLQEQ 1402 Query: 985 --NLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSM 1042 +LE + +K Q Q D EQ KL ++E A +K+ Q S + Sbjct: 1403 QRDLEQERRAKEKLQEQQSD-LEQERRAKEKLQEQQSDLEQERRA-KEKLQEQQ-SDLEQ 1459 Query: 1043 VSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTF 1102 + KL + + LE +++ +Q D +Q + L +Q D +E + + Sbjct: 1460 ERRAKEKLQEQQSDLEQERLAKEKLQEQQRDLEQERRAKEKLQEQQSDLEQERRAKEKLQ 1519 Query: 1103 EMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEE-EEFIQERSVLQEQS 1161 E + + + ++ D L+ + +E +QE+ EQ Sbjct: 1520 EQQSDLEQERLANEKLQEQQRDLEQERRAKEKLQEQQSDLEQERRAKEKLQEQQSDLEQE 1579 Query: 1162 AKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQ 1205 + +LQE + + Q E L E + EQ K KL++ Sbjct: 1580 RRAKEKLQEQQSDLEQ-ERLAKEKLQEQQRDLEQERLAKEKLQE 1622 Score = 119 bits (286), Expect = 8e-25 Identities = 227/1079 (21%), Positives = 465/1079 (43%), Gaps = 90/1079 (8%) Query: 525 NMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLH 584 N++ N K+ + I + S S+ R+ EE H ++ EK Sbjct: 15 NLLIFHINGKIIKNSEKDEIIKSNLRSGSSNSRNRINEEKHEKKHVLSHNSYEKTK---- 70 Query: 585 LVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKL 644 + ++ + + D M ++N+++T K SLL + + + + + + K ++ E KL Sbjct: 71 --NNENNKFFDKDKELTMSNVKNVSQTNFK--SLLRN--LGVSENIFLKENKLNK-EGKL 123 Query: 645 ADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALV----IENLKLDKEQLYGTIKDLE 700 + D IK Q D + KE +E +L KE+L D E Sbjct: 124 IEHIINDDDDKKKYIKGQDENRQEDLEEKAAKETLQGQQSDLEQERLAKEKLQEQQSDSE 183 Query: 701 NDK--EDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKIN-HEEQSKIQTQFGIDAKI 757 ++ ++ + + Q+ +++ +KL++ ++ E LAK E+QS ++ + K+ Sbjct: 184 QERLAKEKLQEQQSDLEQERLAKEKLQEQQSDLEQERLAKEKLQEQQSDLEQERRAKEKL 243 Query: 758 QER--DL--------YIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQ 807 QE+ DL ++ +S+L + + +L+E + +E R + E+ +Q Q Sbjct: 244 QEQQSDLEQERRAKEKLQEQQSDLEQERRAKEKLQEQQSDLEQERLAKEKLQEQQSDLEQ 303 Query: 808 EKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQL-LEIEHENKELQKKNQILLEE----N 862 E++ Q D RLA +++ E+Q LE E KE ++ Q LE+ Sbjct: 304 ERRAKEKLQEQQSDLEQERLA----KEKLQEQQSDLEQERLAKEKLQEQQSDLEQERLAK 359 Query: 863 QNLQISLSDMQQHYNALVE-KANRTDLAESE--STKYQTQLRDLESN--LKRITHEHQTL 917 + LQ SD++Q A + + ++DL + K Q Q DLE K E Q+ Sbjct: 360 EKLQGQQSDLEQERLAKEKLQEQQSDLEQDRLAKEKLQEQQSDLEQERLAKEKLQEQQSD 419 Query: 918 IVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMN 977 + Q+++ E L+ E + +E K+ L E+ + ++E + + +LQE ++++E Sbjct: 420 LEQERRAKEKLQ-EQQSDLEQERLAKEKLQEQ-QSDLEQERRAKEKLQEQQSDLEQERRA 477 Query: 978 VEELNKMNLELIDKHVQKQ--QTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNA 1035 E+L + +L + + K+ Q Q D ++ + + KL ++E +A +K+ Sbjct: 478 KEKLQEQQSDLEQERLAKEKLQEQQSDLEQERLAK-EKLQEQQSDSEQERLA-KEKLQEQ 535 Query: 1036 QVSYMSMVSDYE-SKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQ-DDQIK 1093 Q SD E +LA+ + + + E +R++K+ L +Q + E + L +E+ +Q Sbjct: 536 Q-------SDLEQERLAKEKLQEQQSDLEQERLAKEKLQEQQSDLEQERLAKEKLQEQQS 588 Query: 1094 ELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQE 1153 +L++ +L E K +G E ++ + K+QE++ +++ Sbjct: 589 DLEQERLAKE----KLQGQQSDLEQERLAKEKLQGQQSDLEQERLAKE-KLQEQQSDLEQ 643 Query: 1154 RSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNL 1213 + +E+ + ++L+ L+ ++L + + +E++ + +S LEQ + L Sbjct: 644 ERLAKEKLQEQQSDLERTKASKETLQEQQSDLE-QERLAKEKLQEQQSDLEQERRAKEKL 702 Query: 1214 LSTVAEL----RSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYE 1269 ++L R+ Q E K+ L ++++D ++ E + +L +S E Sbjct: 703 QEQQSDLEQERRAKEKLQEQQSDLEQERRAKEKLQEQQSDLEQ-ERRAKEKLQEQQSDLE 761 Query: 1270 QLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHL---RNLQEKYADVINQIEILRSE 1326 Q D + +E +EQ + KLQ+++ L R +EK + + +E R Sbjct: 762 Q--DRLAKEKLQEQQS--DLEQERRAKEKLQEQQSDLEQDRLAKEKLQEQQSDLEQERRA 817 Query: 1327 IE--DEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXX 1384 E E+ + DL E ++ +++QEQ + E +L K Sbjct: 818 KEKLQEQQSDLEQERLAKEKLQEQQSDLEQERRAKEKLQEQ---QSDLEQDRLAKEKLQE 874 Query: 1385 XXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQL--V 1442 R A+ K+ E LE ++ +K E L Q E +++Q + Sbjct: 875 QQSDLEQERR---AKEKLQEQQSDLE-QERRAKEKLQEQQSDLEQERLAKEKLQEQQRDL 930 Query: 1443 EYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLN 1502 E E+R ++ E++S+L R + E ++ ++ + + KL E+ + E ++ Sbjct: 931 EQERRAKEKLQEQQSDLEQER-RAKEKLQEQQSDLEQERLAKEKLQEQQSDLEQERLAKE 989 Query: 1503 KQVAELNKALEEEVA--KTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVS 1559 K + + +E +A K Q+ LE + + L + ++L+ R + K+Q+ S Sbjct: 990 KLQEQQSDLEQERLAKEKLQGQQSDLEQERLAKEKLQGQQSDLE-QERLAKEKLQEQQS 1047 Score = 87.0 bits (206), Expect = 4e-15 Identities = 209/1020 (20%), Positives = 421/1020 (41%), Gaps = 79/1020 (7%) Query: 151 IKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXX 210 ++++ A LQ + +E L +EK+ E+ +E + +A Sbjct: 845 LEQERRAKEKLQEQQSDLEQDRL-AKEKLQEQQSDLEQERRAKEKLQEQQSDLEQERRAK 903 Query: 211 XEDTKQQMTKMQENFIA--MEAEWKD-EKQRLLKDIESKDVRISSLEEANKLLEAARFEI 267 + +QQ QE ++ + +D E++R K E + S LE+ + E + + Sbjct: 904 EKLQEQQSDLEQERLAKEKLQEQQRDLEQERRAK--EKLQEQQSDLEQERRAKEKLQEQQ 961 Query: 268 S-LEHSKLAQE-LEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELT 325 S LE +LA+E L++ L +Q + E + + +G L Sbjct: 962 SDLEQERLAKEKLQEQQSDLEQERLAKEKLQEQQSDLEQERLAKEKLQGQQSDLEQERLA 1021 Query: 326 K-KIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKS 384 K K++ + Q R ++L+ + + + E A ++ S L + + +S Sbjct: 1022 KEKLQGQQSDLEQERLAKEKLQEQQSDLEQERLAKEKLQEQQSDLEQERLAKEKLQGQQS 1081 Query: 385 PWSQ--LSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXX 442 Q L+ E L Q + + +AK ++ Q DL ++E + EK Sbjct: 1082 DLEQERLAKEKL-QGQQSDLEQERLAKEKL--QGQQSDL-EQERLAKEK----LQGQQSD 1133 Query: 443 XGKDTLIAQLQLEHQQHMEGPSLIH--VGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKD 500 ++ L + E Q +E L + D+ + + +E+L+++ +D + K+ Sbjct: 1134 LEQERLAKEKLQEQQSDLEQERLAKEKLQEQQSDLEQERRAKEKLQEQQSDLERTKASKE 1193 Query: 501 LIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNF----SKVSDSNKE 556 +++ +S EQ +++ ++ + + K KL++ Q ++ K+ + + Sbjct: 1194 TLQEQQSDLEQERLAKEKLQEQQSDL-EQERRAKEKLQEQQSDLEQERLAKEKLQEQQSD 1252 Query: 557 IVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAI 616 + + L ++ ++LE+E+ + L + S E +K+ E ++ E A Sbjct: 1253 LEQERRAKEKLQEQQSDLEQER-RAKEKLQEQQSDLEQERRAKEKLQEQQSDLEQERLAK 1311 Query: 617 SLLESQKFDLVQEL----HILQQKYDEVEDKLAD--ISQLQSDQVCSEIKSVHLEEQIDA 670 L+ Q+ DL QE + +Q+ D +++ A + + QSD + L+EQ Sbjct: 1312 EKLQEQQSDLEQERLAKEKLQEQQSDLEQERRAKEKLQEQQSDLEQERLAKEKLQEQQSD 1371 Query: 671 LSASKK------ELALVIENLKLDKEQLYGTIKDLENDK--EDIMNKLQNYIQENMDLTD 722 L ++ E +E +L KE+L +DLE ++ ++ + + Q+ +++ + Sbjct: 1372 LEQERRAKEKLQEQQSDLEQDRLAKEKLQEQQRDLEQERRAKEKLQEQQSDLEQERRAKE 1431 Query: 723 KLEKMSAEKISELLAKIN-HEEQSKIQTQFGIDAKIQER--DLYIENIESELSKYKSRIC 779 KL++ ++ E AK E+QS ++ + K+QE+ DL E + E + + R Sbjct: 1432 KLQEQQSDLEQERRAKEKLQEQQSDLEQERRAKEKLQEQQSDLEQERLAKEKLQEQQRDL 1491 Query: 780 RLEESIAV-MEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVE 838 E +++++ LE++ + LQE+Q + + ++L + L R E Sbjct: 1492 EQERRAKEKLQEQQSDLEQER-RAKEKLQEQQSDLEQERLANEKLQEQQRDLEQERRAKE 1550 Query: 839 K---QLLEIEHENK---ELQKKNQILLEEN---QNLQISLSDMQQHYNA---LVEKANRT 886 K Q ++E E + +LQ++ L +E + LQ SD++Q A L E+ Sbjct: 1551 KLQEQQSDLEQERRAKEKLQEQQSDLEQERRAKEKLQEQQSDLEQERLAKEKLQEQQRDL 1610 Query: 887 DLAESESTKYQTQLRDLES-------NLKRITHEHQTLIVQK---KKEIEDLEIEFNTQI 936 + K Q Q RDLE NL+R EH ++ + + EI +E+ + Sbjct: 1611 EQERLAKEKLQEQQRDLEQRKADTKKNLER-KKEHGDVLAEDLYGRLEIPAIELPSENER 1669 Query: 937 ESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVE---ELNKMNLELIDKHV 993 I + L + N E + E K N E++ NVE +++K +LE K Sbjct: 1670 GYYIPHQSSLPQDNRGNSR--DSKEISIIE-KTNRESITTNVEGRRDIHKGHLEE-KKDG 1725 Query: 994 QKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQF 1053 + Q D + N + + D +I +I+ + + + L +F Sbjct: 1726 SIKPEQKEDKSADIQNHTLETVNISDVNDFQISKYEDEISAEYDDSLIDEEEDDEDLDEF 1785 Query: 1054 T--TKLENMEEEMQ-RVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTE 1110 + +N ++E + K+L D + NE L L + +EL E K+ KT+ Sbjct: 1786 KPIVQYDNFQDEENIGIYKELEDLIEKNENLDDLDEGIEKSSEELSEEKIKKGKKYEKTK 1845 >UniRef50_Q2NJC3 Cluster: Putative uncharacterized protein; n=1; Aster yellows witches'-broom phytoplasma AYWB|Rep: Putative uncharacterized protein - Aster yellows witches'-broom phytoplasma (strain AYWB) Length = 1062 Score = 145 bits (352), Expect = 8e-33 Identities = 198/879 (22%), Positives = 400/879 (45%), Gaps = 53/879 (6%) Query: 472 TEDVNEIAKVQEQLKQ-ELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVK 530 T+D N I + ++LK+ EL E + + E+LK+ + I L D++ + K K Sbjct: 175 TKD-NSIKTLTDKLKEKELELEEEKNQLITAKEELKTKDNSIKTLTDKLKEKELELEKEK 233 Query: 531 SNHKLKLKQMQKTIDNFSK-VSDSNKEI-VRLTEELHHLSQKVAELEEEKGNLQLHLVDY 588 N + K+ KT DN K ++D KE + L EE + L EL+ + +++ L D Sbjct: 234 -NQLITAKEELKTKDNSIKTLTDKLKEKELELEEEKNQLITAKQELKTKDNSIKT-LTDK 291 Query: 589 DSGRMIESDVYK-KMIEMENLAETRLKAISLL----ESQKFDLVQELHILQQKYDEVEDK 643 + +E + K ++I + +T+ +I L + ++ +L +E + L E++ K Sbjct: 292 LKEKELELEEEKNQLITAKEELKTKDNSIKTLTDKLKEKELELEEEKNQLITAKQELKTK 351 Query: 644 LADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDK 703 I L +D++ + K + LEE+ + L +K+EL ++K ++ +LE K Sbjct: 352 DNSIKTL-TDKL--KEKELELEEEKNQLITAKEELKTKDNSIKTLTDKFKEKELELEEKK 408 Query: 704 EDIMNKLQNYIQE-NMDLTDKLE-KMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERD 761 ++ Q +E N +T K E K I L K+ +E + + + QE Sbjct: 409 NQLITAKQELEEEKNQLITAKEELKTKDNSIKTLTDKLKEKELELEEEKNQLITAKQELK 468 Query: 762 LYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQED 821 +I++ K K + LEE + + LE + +QL + +E + + D Sbjct: 469 TKDNSIKTLTDKLKEKELELEEEKNQLITAKQELEEEKNQLITAKEELKTKDNSIKTLTD 528 Query: 822 ELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVE 881 +L + L + + E+E E +L + L ++ +++ ++ L E Sbjct: 529 KLKEKELELEEKKNQLITAKQELEEEKNQLITAKEELKTKDNSIKTLTDKFKEKELELEE 588 Query: 882 KANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIR 941 K N+ A+ E + + QL + LK + +TL K KE E+E + I Sbjct: 589 KKNQLITAKQELEEEKNQLITAKEELKTKDNSIKTL-TDKFKE---KELELEEKKNQLIT 644 Query: 942 DKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSP 1001 K+ L E EKN + +T E +L+ N+I+ L ++ + LEL +K + Q + Sbjct: 645 AKQELEE--EKN-QLITAKE-ELKTKDNSIKTL---TDKFKEKELELEEK--KNQLITAK 695 Query: 1002 DYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENME 1061 E+ N++ LK KD I L K ++ + E K Q T + +E Sbjct: 696 QELEEEKNQLITAKEELKTKDNSIKTLTDKFKEKEL-------ELEEKKNQLITAKQELE 748 Query: 1062 EEMQRV--SKQLLDSKQHN-EELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTI 1118 EE ++ +K+ L +K ++ + L ++E++ +++E K +T + + + + +I++ Sbjct: 749 EEKNQLITAKEELKTKDNSIKTLTDKLKEKELELEEKKNQLITAKQELEEEKNQLITAKE 808 Query: 1119 EPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQL 1178 E + D N++ L+ +++ + I + L+E+ +L T +E TK + Sbjct: 809 ELKTKD-NSIKTLTDKFKEKELELE-EKKNQLITAKQELEEEKNQLITAKEELKTKDNSI 866 Query: 1179 ETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELR---SSISSAVD---QRG 1232 +TL +L ++ +E+ NQL + E+L E + L++ EL+ +SI + D ++ Sbjct: 867 KTLTDKLKEKELELEEKKNQLITAKEELEEEKNQLITAKEELKTKDNSIKTLTDKLKEKE 926 Query: 1233 FEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQV 1292 E+ E Q + +E + + ++ ++ F+ K +L + + Q+ Sbjct: 927 LELEEEKNQLITAKE-ELKTKDNSIKTLTDKFKEKELELEEEKNQLITAKEELEEEKNQL 985 Query: 1293 TSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEK 1331 + + +L+ K+ ++ L +K+ + ++E+ E+E+EK Sbjct: 986 ITAKVELKTKDNSIKTLTDKFKE--KELEL---ELEEEK 1019 Score = 144 bits (349), Expect = 2e-32 Identities = 203/1020 (19%), Positives = 449/1020 (44%), Gaps = 81/1020 (7%) Query: 569 QKVAELEE-EKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAIS--LLESQKFD 625 QK+ + ++ K + Q+ ++Y + ++Y K E E + K ++ +++D Sbjct: 38 QKILKFQKTNKMHKQIQQINYKNE--YNPNIYNKKTE-EKCEKQNPKTCQKPIIPLEEYD 94 Query: 626 LVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENL 685 ++EL + KY + I+ L+ K + ++ D L + + + L Sbjct: 95 PIEELKL--SKYMSEPAVVTVINALKDKHEQLYKKHLLVKYLTDYLMTKNNSIKTLTDKL 152 Query: 686 KLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQS 745 K KE+L L KE++ K N I+ LTDKL++ E E I +E+ Sbjct: 153 KEKKEELEEEKNQLITAKEELKTK-DNSIKT---LTDKLKEKELELEEEKNQLITAKEEL 208 Query: 746 KIQTQF--GIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLG 803 K + + K++E++L +E +++L K + + SI + D+ L+ K +L Sbjct: 209 KTKDNSIKTLTDKLKEKELELEKEKNQLITAKEELKTKDNSIKTLTDK---LKEKELELE 265 Query: 804 SYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQ 863 + A E ++ N + L D ++ EK+L E+E E +L + L ++ Sbjct: 266 EEKNQLITAKQELKTKD----NSIKTLTD--KLKEKEL-ELEEEKNQLITAKEELKTKDN 318 Query: 864 NLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRIT---HEHQTLIVQ 920 +++ +++ L E+ N+ A+ E ++ L LK E + ++ Sbjct: 319 SIKTLTDKLKEKELELEEEKNQLITAKQELKTKDNSIKTLTDKLKEKELELEEEKNQLIT 378 Query: 921 KKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEE 980 K+E++ + T + ++K++ E EK + +T + +L+E KN + ++ Sbjct: 379 AKEELKTKDNSIKT-LTDKFKEKEL--ELEEKKNQLITAKQ-ELEEEKNQLITAKEELKT 434 Query: 981 LNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYM 1040 + L DK +K+ E+ N++ LK KD I L K+ ++ Sbjct: 435 KDNSIKTLTDKLKEKELE-----LEEEKNQLITAKQELKTKDNSIKTLTDKLKEKEL--- 486 Query: 1041 SMVSDYESKLAQFTTKLENMEEEMQRV--SKQLLDSKQHN-EELQILVREQDDQIKELKE 1097 + E + Q T + +EEE ++ +K+ L +K ++ + L ++E++ +++E K Sbjct: 487 ----ELEEEKNQLITAKQELEEEKNQLITAKEELKTKDNSIKTLTDKLKEKELELEEKKN 542 Query: 1098 TKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVL 1157 +T + + + + +I++ E + D N++ L+ +++ + I + L Sbjct: 543 QLITAKQELEEEKNQLITAKEELKTKD-NSIKTLTDKFKEKELELE-EKKNQLITAKQEL 600 Query: 1158 QEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTV 1217 +E+ +L T +E TK ++TL + ++ +E+ NQL + ++L E + L++ Sbjct: 601 EEEKNQLITAKEELKTKDNSIKTLTDKFKEKELELEEKKNQLITAKQELEEEKNQLITAK 660 Query: 1218 AELRS---SISSAVD---QRGFEIAELWKQHL-AQREADFQKTEH-ELRVQLSAFESKYE 1269 EL++ SI + D ++ E+ E Q + A++E + +K + + +L ++ + Sbjct: 661 EELKTKDNSIKTLTDKFKEKELELEEKKNQLITAKQELEEEKNQLITAKEELKTKDNSIK 720 Query: 1270 QLLDSVQSST---QEETNKIVTMEQ-VTSLQNKLQDKEEHLRNLQEKYADVINQIEILRS 1325 L D + +E+ N+++T +Q + +N+L +E L+ + ++++ Sbjct: 721 TLTDKFKEKELELEEKKNQLITAKQELEEEKNQLITAKEELKTKDNSIKTLTDKLKEKEL 780 Query: 1326 EIEDEK---VAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQE---QSILNINEENAQL-- 1377 E+E++K + +L+T++ S K + + + L + E+ QL Sbjct: 781 ELEEKKNQLITAKQELEEEKNQLITAKEELKTKDNSIKTLTDKFKEKELELEEKKNQLIT 840 Query: 1378 -KKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFEN 1436 K+ + + + LT +L+ K+ E+ +K ++ L +E E Sbjct: 841 AKQELEEEKNQLITAKEELKTKDNSIKTLTDKLKEKELELEEKKNQ----LITAKEELEE 896 Query: 1437 VRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKIT 1496 + QL+ ++ ++ K++ + L K+ E E +E + + + EEL K Sbjct: 897 EKNQLITAKEELKT----KDNSIKTLTDKLKEK----ELELEEEKNQLITAKEELKTKDN 948 Query: 1497 ESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQK 1556 +L + E LEEE + + LE ++ +++T E+ N ++ + K ++ Sbjct: 949 SIKTLTDKFKEKELELEEEKNQLITAKEELEEEKNQLITAKVELKTKDNSIKTLTDKFKE 1008 Score = 140 bits (339), Expect = 3e-31 Identities = 188/879 (21%), Positives = 396/879 (45%), Gaps = 67/879 (7%) Query: 768 ESELSKYKSRICRLEESIAVMEDRRYSLERK---ADQLGSYLQEKQKAYSEYTIQEDELV 824 E +LSKY S + I ++D+ L +K L YL K + T + E Sbjct: 98 ELKLSKYMSEPA-VVTVINALKDKHEQLYKKHLLVKYLTDYLMTKNNSIKTLTDKLKEKK 156 Query: 825 NRLAVLMDHDRVVEKQLLEIEHENKELQ---KKNQILLEENQNLQISLSD-MQQHYNALV 880 L + +++L ++ K L K+ ++ LEE +N I+ + ++ N++ Sbjct: 157 EELEEEKNQLITAKEELKTKDNSIKTLTDKLKEKELELEEEKNQLITAKEELKTKDNSIK 216 Query: 881 EKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAI 940 ++ E E K + QL + LK + +TL + K++ +LE E N Q+ +A Sbjct: 217 TLTDKLKEKELELEKEKNQLITAKEELKTKDNSIKTLTDKLKEKELELEEEKN-QLITAK 275 Query: 941 RDKKVLNEKYEKNIEYVTQLEAQLQEYKNNI----ENLNMNVEELNKMNLELIDKHVQKQ 996 ++ K + + + + + E +L+E KN + E L + + +L +K ++ + Sbjct: 276 QELKTKDNSIKTLTDKLKEKELELEEEKNQLITAKEELKTKDNSIKTLTDKLKEKELELE 335 Query: 997 QTQSPDYT--EQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFT 1054 + ++ T ++ + N + L + E+ + L ++ N ++ + ++ + T Sbjct: 336 EEKNQLITAKQELKTKDNSIKTLTDKLKEKELELEEE-KNQLITAKEELKTKDNSIKTLT 394 Query: 1055 TKLENMEEEMQRVSKQLLDSKQHNEELQ---ILVREQ----DDQIKELKETKLTFEMNIP 1107 K + E E++ QL+ +KQ EE + I +E+ D+ IK L + E+ + Sbjct: 395 DKFKEKELELEEKKNQLITAKQELEEEKNQLITAKEELKTKDNSIKTLTDKLKEKELELE 454 Query: 1108 KTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTE 1167 + + +I++ E + D N++ L+ +E+ + I + L+E+ +L T Sbjct: 455 EEKNQLITAKQELKTKD-NSIKTLTDKLKEKELELE-EEKNQLITAKQELEEEKNQLITA 512 Query: 1168 LQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELR---SSI 1224 +E TK ++TL +L ++ +E+ NQL + ++L E + L++ EL+ +SI Sbjct: 513 KEELKTKDNSIKTLTDKLKEKELELEEKKNQLITAKQELEEEKNQLITAKEELKTKDNSI 572 Query: 1225 SSAVD---QRGFEIAELWKQHL-AQREADFQKTE-HELRVQLSAFESKYEQLLDSVQS-- 1277 + D ++ E+ E Q + A++E + +K + + +L ++ + L D + Sbjct: 573 KTLTDKFKEKELELEEKKNQLITAKQELEEEKNQLITAKEELKTKDNSIKTLTDKFKEKE 632 Query: 1278 -STQEETNKIVTMEQ-VTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEK---V 1332 +E+ N+++T +Q + +N+L +E L+ + ++ + E+E++K + Sbjct: 633 LELEEKKNQLITAKQELEEEKNQLITAKEELKTKDNSIKTLTDKFKEKELELEEKKNQLI 692 Query: 1333 AFXXXXXXXXXXXXXXXXDLRTENQSYKQMQE---QSILNINEENAQL---KKSSXXXXX 1386 +L+T++ S K + + + L + E+ QL K+ Sbjct: 693 TAKQELEEEKNQLITAKEELKTKDNSIKTLTDKFKEKELELEEKKNQLITAKQELEEEKN 752 Query: 1387 XXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFEN----VRQQLV 1442 + + + LT +L+ K+ E+ +K ++ IT Q +E +N +++L Sbjct: 753 QLITAKEELKTKDNSIKTLTDKLKEKELELEEKKNQ-LITAKQELEEEKNQLITAKEELK 811 Query: 1443 EYEKRIEDLTYE-KESELAILRLKMHENANHYETMQKESEIERVKLI---EELNVKITES 1498 + I+ LT + KE E L++ E N T ++E E E+ +LI EEL K Sbjct: 812 TKDNSIKTLTDKFKEKE-----LELEEKKNQLITAKQELEEEKNQLITAKEELKTKDNSI 866 Query: 1499 VSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKI-QKH 1557 +L ++ E LEE+ + + LE ++ +++T +E+ N ++ + K+ +K Sbjct: 867 KTLTDKLKEKELELEEKKNQLITAKEELEEEKNQLITAKEELKTKDNSIKTLTDKLKEKE 926 Query: 1558 VSFASDTKQ--GRDEQL---DNTMNKELLDAVPRAELDL 1591 + + Q E+L DN++ K L D EL+L Sbjct: 927 LELEEEKNQLITAKEELKTKDNSI-KTLTDKFKEKELEL 964 Score = 129 bits (311), Expect = 7e-28 Identities = 207/882 (23%), Positives = 383/882 (43%), Gaps = 71/882 (8%) Query: 151 IKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXX 210 +K KDN++ L K+K E L+L+E EK+Q+I AK + T Sbjct: 173 LKTKDNSIKTLTDKLKEKE---LELEE---EKNQLITAKEELKTKDNSIKTLTDKLKEKE 226 Query: 211 XEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAAR------ 264 E K+ K Q E + KD + L D + K+ + EE N+L+ A + Sbjct: 227 LELEKE---KNQLITAKEELKTKDNSIKTLTD-KLKEKELELEEEKNQLITAKQELKTKD 282 Query: 265 -----FEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEK-TEIEEKGSLEI 318 L+ +L E E+ + +++ +EK E+EE+ + I Sbjct: 283 NSIKTLTDKLKEKELELEEEKNQLITAKEELKTKDNSIKTLTDKLKEKELELEEEKNQLI 342 Query: 319 ANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNT 378 EL K ++ L ++++ ELE + + T + + + L + + Sbjct: 343 TAKQELKTKDNSIKTLTDKLKEKELELEEEKNQLITAKEELKTKDNSIKTLTDKFKEKEL 402 Query: 379 ASKMKSPWSQLSSETLNQDTDKKIN-KNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXX 437 + K + + L ++ ++ I K E+ + I++L L +KE + E+ Sbjct: 403 ELEEKKNQLITAKQELEEEKNQLITAKEELKTKDNSIKTLTDKLKEKELELEEEKNQLIT 462 Query: 438 XXXXXXGKDTLIAQL-----QLEHQQHMEGPSLIHVGTN-TEDVNEIAKVQEQLKQELND 491 KD I L + E + E LI E+ N++ +E+LK Sbjct: 463 AKQELKTKDNSIKTLTDKLKEKELELEEEKNQLITAKQELEEEKNQLITAKEELK----- 517 Query: 492 EIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSK-V 550 KD ++K L +KLK E ++ + +++ A K ++ + N + K+ KT DN K + Sbjct: 518 -TKDNSIKTLTDKLKEKELELEEKKNQLITA-KQELEEEKNQLITAKEELKTKDNSIKTL 575 Query: 551 SDSNKE-IVRLTEELHHLSQKVAELEEEKGNL---QLHLVDYDSGRMIESDVYK-KMIEM 605 +D KE + L E+ + L ELEEEK L + L D+ +D +K K +E+ Sbjct: 576 TDKFKEKELELEEKKNQLITAKQELEEEKNQLITAKEELKTKDNSIKTLTDKFKEKELEL 635 Query: 606 ENLAETRLKAISLLESQKFDLV---QELHILQQKYDEVEDKLADISQLQSDQVCSEIKSV 662 E + A LE +K L+ +EL + DK + +L+ ++ +++ + Sbjct: 636 EEKKNQLITAKQELEEEKNQLITAKEELKTKDNSIKTLTDKFKE-KELELEEKKNQLITA 694 Query: 663 --HLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQE-NMD 719 LEE+ + L +K+EL ++K ++ +LE K ++ Q +E N Sbjct: 695 KQELEEEKNQLITAKEELKTKDNSIKTLTDKFKEKELELEEKKNQLITAKQELEEEKNQL 754 Query: 720 LTDKLE-KMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRI 778 +T K E K I L K+ +E + + + QE +E +++L K + Sbjct: 755 ITAKEELKTKDNSIKTLTDKLKEKELELEEKKNQLITAKQE----LEEEKNQLITAKEEL 810 Query: 779 CRLEESIAVMED----RRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNR-LAVLMDH 833 + SI + D + LE K +QL + QE ++ ++ ++EL + ++ Sbjct: 811 KTKDNSIKTLTDKFKEKELELEEKKNQLITAKQELEEEKNQLITAKEELKTKDNSIKTLT 870 Query: 834 DRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESES 893 D++ EK+ LE+E + +L + L EE L + +++ N++ ++ E E Sbjct: 871 DKLKEKE-LELEEKKNQLITAKEELEEEKNQLITAKEELKTKDNSIKTLTDKLKEKELEL 929 Query: 894 TKYQTQLRDLESNLKRITHEHQTLIVQ-KKKEIEDLEIEFNTQIESAIRDKKVLNEKYEK 952 + + QL + LK + +TL + K+KE+E LE E N I + K+ L E EK Sbjct: 930 EEEKNQLITAKEELKTKDNSIKTLTDKFKEKELE-LEEEKNQLITA----KEELEE--EK 982 Query: 953 NIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQ 994 N + +T + +L+ N+I+ L +E ++ LEL ++ Q Sbjct: 983 N-QLIT-AKVELKTKDNSIKTLTDKFKE-KELELELEEEKNQ 1021 Score = 128 bits (309), Expect = 1e-27 Identities = 216/933 (23%), Positives = 407/933 (43%), Gaps = 99/933 (10%) Query: 305 EEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELE---NKLATMGTESKAVSS 361 E+K E+EE+ + I EL K ++ L ++++ ELE N+L T E K + Sbjct: 154 EKKEELEEEKNQLITAKEELKTKDNSIKTLTDKLKEKELELEEEKNQLITAKEELKTKDN 213 Query: 362 PSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDL 421 K + + K K K+ E +D K +++ + E+ ++ L Sbjct: 214 SIKTLTDKLKEK--ELELEKEKNQLITAKEELKTKDNSIKTLTDKLKEKELELEEEKNQL 271 Query: 422 VDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKV 481 + + + KD K +L+LE +++ + + T + + Sbjct: 272 ITAKQELKTKDNSIKTLTDKLKEK-----ELELEEEKNQLITAKEELKTKDNSIKTLTDK 326 Query: 482 QEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQ 541 ++ + EL +E + ++LK+ + I L D++ + + K N + K+ Sbjct: 327 LKEKELELEEEKNQLITAK--QELKTKDNSIKTLTDKLKEKELELEEEK-NQLITAKEEL 383 Query: 542 KTIDNFSK-VSDSNKE-IVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVY 599 KT DN K ++D KE + L E+ + L ELEEEK L+ + + Sbjct: 384 KTKDNSIKTLTDKFKEKELELEEKKNQLITAKQELEEEKN----QLITAKEELKTKDNSI 439 Query: 600 KKMIEMENLAETRLKAISLLESQKFDLV---QELHILQQKYDEVEDKLADISQLQSDQVC 656 K + + L E L+ LE +K L+ QEL + DKL + Sbjct: 440 KTL--TDKLKEKELE----LEEEKNQLITAKQELKTKDNSIKTLTDKLKE---------- 483 Query: 657 SEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQE 716 K + LEE+ + L +K+EL L KE+L K +N + + +KL+ ++ Sbjct: 484 ---KELELEEEKNQLITAKQELEEEKNQLITAKEEL----KTKDNSIKTLTDKLK---EK 533 Query: 717 NMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKS 776 ++L +K ++ K EL EE++++ I AK +E +I++ K+K Sbjct: 534 ELELEEKKNQLITAK-QEL-----EEEKNQL-----ITAK-EELKTKDNSIKTLTDKFKE 581 Query: 777 RICRLEESIAVMEDRRYSLERKADQLGSYLQE-KQKAYSEYTIQEDELVNRLAVLMDHDR 835 + LEE + + LE + +QL + +E K K S T+ + L + ++ Sbjct: 582 KELELEEKKNQLITAKQELEEEKNQLITAKEELKTKDNSIKTLTDKFKEKELELEEKKNQ 641 Query: 836 VV-EKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESEST 894 ++ KQ LE E +N+ + K ++ ++N +++ ++ L EK N+ A+ E Sbjct: 642 LITAKQELE-EEKNQLITAKEELKTKDN-SIKTLTDKFKEKELELEEKKNQLITAKQELE 699 Query: 895 KYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNI 954 + + QL + LK + +TL K KE E+E + I K+ L E EKN Sbjct: 700 EEKNQLITAKEELKTKDNSIKTL-TDKFKE---KELELEEKKNQLITAKQELEE--EKN- 752 Query: 955 EYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKL 1014 + +T E +L+ N+I+ L ++L + LEL +K + Q + E+ N++ Sbjct: 753 QLITAKE-ELKTKDNSIKTL---TDKLKEKELELEEK--KNQLITAKQELEEEKNQLITA 806 Query: 1015 NALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDS 1074 LK KD I L K ++ + E K Q T + +EEE QL+ + Sbjct: 807 KEELKTKDNSIKTLTDKFKEKEL-------ELEEKKNQLITAKQELEEE----KNQLITA 855 Query: 1075 KQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXX 1134 K EEL + +D+ IK L + E+ + + + +I++ E + ++ N + Sbjct: 856 K---EEL----KTKDNSIKTLTDKLKEKELELEEKKNQLITAK-EELEEEKNQLITAKEE 907 Query: 1135 XXXXXXXLKVQEEEEFIQERSV-LQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQ 1193 +K ++ ++E+ + L+E+ +L T +E TK ++TL + ++ + Sbjct: 908 LKTKDNSIKTLTDK--LKEKELELEEEKNQLITAKEELKTKDNSIKTLTDKFKEKELELE 965 Query: 1194 EQINQLKSKLEQLNTENDNLLSTVAELRSSISS 1226 E+ NQL + E+L E + L++ EL++ +S Sbjct: 966 EEKNQLITAKEELEEEKNQLITAKVELKTKDNS 998 Score = 120 bits (290), Expect = 3e-25 Identities = 189/869 (21%), Positives = 369/869 (42%), Gaps = 62/869 (7%) Query: 92 ESLANTLKQKEILMEKIKQYKELSKRSSTT---IVRXXXXXXXXXXXXXXXQLGDVTHLS 148 ++L + LK+KE+ +E+ K +K T ++ + + Sbjct: 181 KTLTDKLKEKELELEEEKNQLITAKEELKTKDNSIKTLTDKLKEKELELEKEKNQLITAK 240 Query: 149 NTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXX 208 +K KDN++ L K+K E L+L+E EK+Q+I AK + T Sbjct: 241 EELKTKDNSIKTLTDKLKEKE---LELEE---EKNQLITAKQELKT-------------- 280 Query: 209 XXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEIS 268 K K++E E E ++EK +L+ E + +S++ L+ E+ Sbjct: 281 -KDNSIKTLTDKLKEK----ELELEEEKNQLITAKEELKTKDNSIKTLTDKLKEKELELE 335 Query: 269 LEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLE-----IANMTE 323 E ++L ++ L ++ +E E+ I K L+ I +T+ Sbjct: 336 EEKNQLITAKQELKTKDNSIKTLTDKLKEKELELEEEKNQLITAKEELKTKDNSIKTLTD 395 Query: 324 LTKKIEL-LEHLNCQIRQTNKELE---NKLATMGTESKAVSSPSKKGSPLISRKSGRNTA 379 K+ EL LE Q+ +ELE N+L T E K + K + + K Sbjct: 396 KFKEKELELEEKKNQLITAKQELEEEKNQLITAKEELKTKDNSIKTLTDKLKEK--ELEL 453 Query: 380 SKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXX 439 + K+ E +D K +++ + E+ ++ L+ + + E+ Sbjct: 454 EEEKNQLITAKQELKTKDNSIKTLTDKLKEKELELEEEKNQLITAKQELEEEKNQLITAK 513 Query: 440 XXXXGKDTLIAQL--QLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVN 497 KD I L +L+ ++ + T +++ E K+EL + KD + Sbjct: 514 EELKTKDNSIKTLTDKLKEKELELEEKKNQLITAKQELEEEKNQLITAKEEL--KTKDNS 571 Query: 498 VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSK-VSDSNKE 556 +K L +K K E ++ + +++ A K ++ + N + K+ KT DN K ++D KE Sbjct: 572 IKTLTDKFKEKELELEEKKNQLITA-KQELEEEKNQLITAKEELKTKDNSIKTLTDKFKE 630 Query: 557 -IVRLTEELHHLSQKVAELEEEKGNL---QLHLVDYDSGRMIESDVYK-KMIEMENLAET 611 + L E+ + L ELEEEK L + L D+ +D +K K +E+E Sbjct: 631 KELELEEKKNQLITAKQELEEEKNQLITAKEELKTKDNSIKTLTDKFKEKELELEEKKNQ 690 Query: 612 RLKAISLLESQKFDLV---QELHILQQKYDEVEDKLADISQLQSDQVCSEIKSV--HLEE 666 + A LE +K L+ +EL + DK + +L+ ++ +++ + LEE Sbjct: 691 LITAKQELEEEKNQLITAKEELKTKDNSIKTLTDKFKE-KELELEEKKNQLITAKQELEE 749 Query: 667 QIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQE-NMDLTDKLE 725 + + L +K+EL ++K ++L +LE K ++ Q +E N +T K E Sbjct: 750 EKNQLITAKEELKTKDNSIKTLTDKLKEKELELEEKKNQLITAKQELEEEKNQLITAKEE 809 Query: 726 -KMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEES 784 K I L K +E + + + QE + + + + K++ ++ Sbjct: 810 LKTKDNSIKTLTDKFKEKELELEEKKNQLITAKQELEEEKNQLITAKEELKTKDNSIKTL 869 Query: 785 IAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNR-LAVLMDHDRVVEKQLLE 843 ++++ LE K +QL + +E ++ ++ ++EL + ++ D++ EK+ LE Sbjct: 870 TDKLKEKELELEEKKNQLITAKEELEEEKNQLITAKEELKTKDNSIKTLTDKLKEKE-LE 928 Query: 844 IEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDL 903 +E E +L + L ++ +++ ++ L E+ N+ A+ E + + QL Sbjct: 929 LEEEKNQLITAKEELKTKDNSIKTLTDKFKEKELELEEEKNQLITAKEELEEEKNQLITA 988 Query: 904 ESNLKRITHEHQTLIVQ-KKKEIEDLEIE 931 + LK + +TL + K+KE+E LE+E Sbjct: 989 KVELKTKDNSIKTLTDKFKEKELE-LELE 1016 Score = 93.9 bits (223), Expect = 3e-17 Identities = 139/700 (19%), Positives = 301/700 (43%), Gaps = 71/700 (10%) Query: 92 ESLANTLKQKEILMEKIKQYKELSKRSSTT---IVRXXXXXXXXXXXXXXXQLGDVTHLS 148 ++L + LK+KE+ +E+ K +K T ++ + + Sbjct: 356 KTLTDKLKEKELELEEEKNQLITAKEELKTKDNSIKTLTDKFKEKELELEEKKNQLITAK 415 Query: 149 NTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXX 208 ++E+ N L + ++K + +I L +K+ EK+ +E + Sbjct: 416 QELEEEKNQLITAKEELKTKDNSIKTLTDKLKEKELELEEEKNQLITAKQELKTKDNSIK 475 Query: 209 XXXEDTKQQMTKMQEN---FIAMEAEWKDEKQRLL---KDIESKDVRISSL--------- 253 + K++ +++E I + E ++EK +L+ +++++KD I +L Sbjct: 476 TLTDKLKEKELELEEEKNQLITAKQELEEEKNQLITAKEELKTKDNSIKTLTDKLKEKEL 535 Query: 254 --EEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEE----- 306 EE L A+ E+ E ++L E+ ++ +E ++ Sbjct: 536 ELEEKKNQLITAKQELEEEKNQLITAKEELKTKDNSIKTLTDKFKEKELELEEKKNQLIT 595 Query: 307 -KTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKK 365 K E+EE+ + I EL K ++ L + ++ ELE K + T + + +K Sbjct: 596 AKQELEEEKNQLITAKEELKTKDNSIKTLTDKFKEKELELEEKKNQLITAKQELE--EEK 653 Query: 366 GSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKE 425 + +++ + + +K+ L+ + ++ + + KN++ + ++ L+ + Sbjct: 654 NQLITAKEELKTKDNSIKT----LTDKFKEKELELEEKKNQLITAKQELEEEKNQLITAK 709 Query: 426 YVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTN-TEDVNEIAKVQEQ 484 + KD K +L+LE +++ LI E+ N++ +E+ Sbjct: 710 EELKTKDNSIKTLTDKFKEK-----ELELEEKKN----QLITAKQELEEEKNQLITAKEE 760 Query: 485 LKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTI 544 LK KD ++K L +KLK E ++ + +++ A K ++ + N + K+ KT Sbjct: 761 LK------TKDNSIKTLTDKLKEKELELEEKKNQLITA-KQELEEEKNQLITAKEELKTK 813 Query: 545 DNFSK-VSDSNKE-IVRLTEELHHLSQKVAELEEEKGNL-----QLHLVDYDSGRMIESD 597 DN K ++D KE + L E+ + L ELEEEK L +L D +S + + Sbjct: 814 DNSIKTLTDKFKEKELELEEKKNQLITAKQELEEEKNQLITAKEELKTKD-NSIKTLTDK 872 Query: 598 VYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQK-------YDEVEDKLADISQL 650 + +K +E+E + A LE +K L+ L+ K D++++K ++ + Sbjct: 873 LKEKELELEEKKNQLITAKEELEEEKNQLITAKEELKTKDNSIKTLTDKLKEKELELEEE 932 Query: 651 QSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMN-K 709 ++ + ++ + + I L+ KE L +E +K QL ++LE +K ++ K Sbjct: 933 KNQLITAKEELKTKDNSIKTLTDKFKEKELELEE---EKNQLITAKEELEEEKNQLITAK 989 Query: 710 LQNYIQEN--MDLTDKLEKMSAE-KISELLAKINHEEQSK 746 ++ ++N LTDK ++ E ++ E ++N+ ++K Sbjct: 990 VELKTKDNSIKTLTDKFKEKELELELEEEKNQLNYSHKNK 1029 >UniRef50_A0DBE4 Cluster: Chromosome undetermined scaffold_44, whole genome shotgun sequence; n=2; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_44, whole genome shotgun sequence - Paramecium tetraurelia Length = 1155 Score = 145 bits (352), Expect = 8e-33 Identities = 230/1157 (19%), Positives = 521/1157 (45%), Gaps = 104/1157 (8%) Query: 212 EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271 E +QQ +Q+ + E+KD + ++LK+IE ++ + L++ N+ L + E + Sbjct: 38 EQGQQQNLDLQKENERITNEFKDRETKMLKEIEQVKLQYAELQKENERLIS---EFKDKE 94 Query: 272 SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELL 331 +KL Q++E L K + E +I++K +LEI N+ + + + Sbjct: 95 TKLLQDIEN-----QKQQNQQLILGK---DMQGNELLQIQQKLNLEIDNLKQQIQNLN-- 144 Query: 332 EHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSS 391 + L Q +Q +++ + K + E K + +K + ++ + N ++ ++ Sbjct: 145 DQLKLQQQQFDEKEKQKNKEI-EELKLLHVQLEKQNETLTNEFKDNETKMLQ----EIEH 199 Query: 392 ETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQ 451 + L Q ++ N+ +++L+ + K++ +++ + + KD I Sbjct: 200 QKLQQLQFQRENEQLMSELKDRENKMLKEIENEK--LQNLEIQKENERLRNEFKDKEIKL 257 Query: 452 LQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQ 511 LQ Q + LI +G + + NE+ ++Q++L E+ D +K +++L ++LK ++Q Sbjct: 258 LQDIENQKQQNQQLI-LGKDMQG-NELLQIQQKLNLEI-DNLKQ-QIQNLNDQLKLQQQQ 313 Query: 512 ITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKV 571 DE K K K +LKL +Q + N + ++ + ++ ++ HL+ ++ Sbjct: 314 F----DE-----KEKQKNKEIEELKLLHVQLELQNETLTNEFKDKETKMILDIDHLTLQL 364 Query: 572 AELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELH 631 +L++ KGN +L + + + + ++ + ++ + I+ L Q+ L +E+ Sbjct: 365 -QLKDTKGN-EL----FQTQQKLNLELENIQLSLQQQQQQHDVKINDLVQQQDQLNKEIT 418 Query: 632 ILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLE-EQIDA-LSASKKELALVI-ENLKLD 688 +Q + ED++ ++ +D++ +IK E Q+ LS + + EN L Sbjct: 419 SYKQLTSQKEDQINQLTN-NNDELSVQIKGKENEINQLQQNLSVITNDYQKSLKENENLT 477 Query: 689 KEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQ 748 KE+L + LEN N +Q+ E L ++ + ++++L +I+ +Q+ Sbjct: 478 KEKLEYEAQLLEN-----KNLIQSMQHEKEQLQNEHQLNKDNQLNDLQTQISQLQQTVTS 532 Query: 749 TQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRR--YSLERKADQLGSYL 806 Q I A ++++L +N +L + +I +L I ME++R + L + Q Sbjct: 533 QQSQI-ATDKDQNLIQQN---KLQEQNVQIQQLTVQIQNMEEQRNEFKLNNQIFQNLKIK 588 Query: 807 QEKQKAYSEYTIQEDELVNRLAVL-MDHDRVVEKQLLEIEHENKELQKKNQILLEENQNL 865 K ++ + ++ N ++ + ++ E Q L+ H+ +L N L+EEN + Sbjct: 589 YVNNKLHNNQYPFKKQIKNYKSIRPIQSSKISEIQALQSAHQ--DLNIANNKLIEENNSF 646 Query: 866 QISLSDMQQHYNAL-----VEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQ 920 QI+ + N L +EK ++E ++ + +Q+ L + ++ E Q L V Sbjct: 647 QINHDQIAIEINNLQEQCRIEKETNQKISE-QNQQLSSQIEQLNEEINKLVKERQQLEVT 705 Query: 921 KKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQ-LEAQLQEYKNNIENLNMNVE 979 +K++ + + E N Q+ + I+++KV + Y + +E + LE Q+ + + + N +E Sbjct: 706 QKQDHNNQQDELN-QL-NQIQEEKVNLQNYNEKLENTNKHLEEQIFQLQQQSQAQNTLLE 763 Query: 980 ELNKM--NLELIDKHVQKQQTQSPD---YTEQYINEINKLN-ALLKQKDEEIIALNQKIN 1033 E ++ +L++ ++ ++ Q Q + ++ IN IN N L+ +K+ E + + Sbjct: 764 EKEQLINSLKMANEQIESQLLQDQNKQQEKDECINSINLENKKLINEKELEQNSFEEHNK 823 Query: 1034 NAQVSY-------MSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVR 1086 ++ + +++++ + ++ Q K++ E + +Q+ + K+H + L+ + Sbjct: 824 QDKLEFENQLNQDVTLIAQLQEEVNQQNHKIQQYENNEKNYQQQIEELKEHIQNLEDFSQ 883 Query: 1087 EQDDQIKEL--KETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKV 1144 ++ I E KE +L E+ K E +S D L+ Sbjct: 884 VSENHISEQQEKEQQLIKELEALKLEYEHLSQQNSSFKDQVEQFQLQNEQSTHKQTLLEN 943 Query: 1145 QEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLE 1204 + +E LQ+Q L + + Y + I L + E ++ E+I++ K++LE Sbjct: 944 EIKE--------LQQQQTDLQNNIHQ-YEEKINLLQIEREQDQTKLMEAEEISKQKTELE 994 Query: 1205 -QLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSA 1263 Q+ +ND + L + D+ E K + Q++ D + +++++ L Sbjct: 995 KQIKHQND----AIQNLCQQVGLLEDEHPNEYIATQKAKMIQQQKDIENLKNDIK-NLQQ 1049 Query: 1264 FESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRN------LQEKYADVI 1317 KY++ Q+E + +EQ++ L N + E ++ + ++Y I Sbjct: 1050 EIKKYQE--KEALIKIQKEKLERKYLEQISELSNHQDEMFEQIKEWRSKALMSDEYLKKI 1107 Query: 1318 NQIEILRSEIEDEKVAF 1334 +E+ +D+ V++ Sbjct: 1108 KDLEMTLKFKQDQLVSY 1124 Score = 117 bits (281), Expect = 3e-24 Identities = 225/1155 (19%), Positives = 495/1155 (42%), Gaps = 123/1155 (10%) Query: 502 IEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLT 561 I++ K E+ I + + + N I+ L L++ + I N K ++ ++ Sbjct: 13 IQQQKENEKFINEFKGK-EIQMLNEIEQGQQQNLDLQKENERITNEFKDRET-----KML 66 Query: 562 EELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLES 621 +E+ + + AEL++E L D ++ ++++ +K + + ++ LL+ Sbjct: 67 KEIEQVKLQYAELQKENERLISEFKDKET-KLLQDIENQKQQNQQLILGKDMQGNELLQI 125 Query: 622 QKFDLVQELHILQQKYDEVEDKLA------DISQLQSDQVCSEIKSVH--LEEQIDALSA 673 Q+ L E+ L+Q+ + D+L D + Q ++ E+K +H LE+Q + L+ Sbjct: 126 QQ-KLNLEIDNLKQQIQNLNDQLKLQQQQFDEKEKQKNKEIEELKLLHVQLEKQNETLTN 184 Query: 674 SKKE----LALVIENLKL-------DKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTD 722 K+ + IE+ KL + EQL +KD EN ++ +++N +N+++ Sbjct: 185 EFKDNETKMLQEIEHQKLQQLQFQRENEQLMSELKDRENK---MLKEIENEKLQNLEIQK 241 Query: 723 KLEKMSAE---KISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRIC 779 + E++ E K +LL I +++Q Q G D + E + + E+ K +I Sbjct: 242 ENERLRNEFKDKEIKLLQDIENQKQQNQQLILGKDMQGNELLQIQQKLNLEIDNLKQQIQ 301 Query: 780 RLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLA-----VLMDHD 834 L + + + + + + K Q ++E + + + +Q + L N +++D D Sbjct: 302 NLNDQLKLQQQQ---FDEKEKQKNKEIEELKLLHVQLELQNETLTNEFKDKETKMILDID 358 Query: 835 RVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHY----NALVEK-------- 882 + + L+ + + EL + Q L E +N+Q+SL QQ + N LV++ Sbjct: 359 HLTLQLQLK-DTKGNELFQTQQKLNLELENIQLSLQQQQQQHDVKINDLVQQQDQLNKEI 417 Query: 883 -----------------ANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLI------V 919 N D + + ++ L+ NL IT+++Q + Sbjct: 418 TSYKQLTSQKEDQINQLTNNNDELSVQIKGKENEINQLQQNLSVITNDYQKSLKENENLT 477 Query: 920 QKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIE-YVTQLEAQLQEYKNNIENLNMNV 978 ++K E E +E I+S +K+ L +++ N + + L+ Q+ + + + + + Sbjct: 478 KEKLEYEAQLLENKNLIQSMQHEKEQLQNEHQLNKDNQLNDLQTQISQLQQTVTSQQSQI 537 Query: 979 EELNKMNL----ELIDKHVQKQQ-TQSPDYTEQYINEINKLNALLKQKDEEIIALNQKIN 1033 NL +L +++VQ QQ T E+ NE KLN + Q + +I +N K++ Sbjct: 538 ATDKDQNLIQQNKLQEQNVQIQQLTVQIQNMEEQRNEF-KLNNQIFQ-NLKIKYVNNKLH 595 Query: 1034 NAQVSYMSMVSDYESKLAQFTTKLENMEE-EMQRVSKQLLDSK--QHNEELQILVREQDD 1090 N Q + + +Y+S ++K+ ++ + + ++K + N QI + Sbjct: 596 NNQYPFKKQIKNYKSIRPIQSSKISEIQALQSAHQDLNIANNKLIEENNSFQINHDQIAI 655 Query: 1091 QIKELKET-KLTFEMNIPKTE-GMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEE 1148 +I L+E ++ E N +E +SS IE ++++ N + +++ Sbjct: 656 EINNLQEQCRIEKETNQKISEQNQQLSSQIEQLNEEINKLVKERQQLEVTQKQDHNNQQD 715 Query: 1149 EF-----IQERSV-LQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSK 1202 E IQE V LQ + KL + +I QL+ + ++ IN LK Sbjct: 716 ELNQLNQIQEEKVNLQNYNEKLENTNKHLEEQIFQLQQQSQAQNTLLEEKEQLINSLKMA 775 Query: 1203 LEQLNTE---NDNLLSTVAELRSSIS----SAVDQRGFEIAELWKQHLAQREADFQKTEH 1255 EQ+ ++ + N E +SI+ ++++ E +++H Q + +F+ + Sbjct: 776 NEQIESQLLQDQNKQQEKDECINSINLENKKLINEKELE-QNSFEEHNKQDKLEFENQLN 834 Query: 1256 ELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQ----VTSLQNKLQDKEEHLRNLQE 1311 + ++ + + Q +Q E N +E+ + +L++ Q E H+ QE Sbjct: 835 QDVTLIAQLQEEVNQQNHKIQQYENNEKNYQQQIEELKEHIQNLEDFSQVSENHISEQQE 894 Query: 1312 KYADVINQIEILRSEIE---DEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSIL 1368 K +I ++E L+ E E + +F K++Q+Q Sbjct: 895 KEQQLIKELEALKLEYEHLSQQNSSFKDQVEQFQLQNEQSTHKQTLLENEIKELQQQQ-T 953 Query: 1369 NINEENAQLKKSSXXXXXXXXXXXXRVNDAE---AKVLELTHQLELKDSEIYQKTHEYTI 1425 ++ Q ++ ++ +AE + EL Q++ ++ I + + Sbjct: 954 DLQNNIHQYEEKINLLQIEREQDQTKLMEAEEISKQKTELEKQIKHQNDAIQNLCQQVGL 1013 Query: 1426 TLTQRNDEF-ENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIER 1484 + +E+ + ++++ +K IE+L + + + +K ++ +QKE ++ER Sbjct: 1014 LEDEHPNEYIATQKAKMIQQQKDIENL--KNDIKNLQQEIKKYQEKEALIKIQKE-KLER 1070 Query: 1485 VKLIEELNVKITESVSLNKQVAE-LNKAL--EEEVAKTNEMQTALENQEIEIVTLNDEIT 1541 K +E+++ + +Q+ E +KAL +E + K +++ L+ ++ ++V+ + +I Sbjct: 1071 -KYLEQISELSNHQDEMFEQIKEWRSKALMSDEYLKKIKDLEMTLKFKQDQLVSYSQKIQ 1129 Query: 1542 NLQNMVRASSSKIQK 1556 + K+Q+ Sbjct: 1130 EQSVQIDQLELKVQE 1144 Score = 112 bits (270), Expect = 7e-23 Identities = 184/909 (20%), Positives = 384/909 (42%), Gaps = 77/909 (8%) Query: 696 IKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDA 755 I + + + ++N+++ Q+N+DL + E+++ E + EQ K+Q A Sbjct: 23 INEFKGKEIQMLNEIEQGQQQNLDLQKENERITNEFKDRETKMLKEIEQVKLQY-----A 77 Query: 756 KIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSE 815 ++Q+ EN E +S++K + +L + I + + L D G+ L + Q+ + Sbjct: 78 ELQK-----EN-ERLISEFKDKETKLLQDIENQKQQNQQLILGKDMQGNELLQIQQ---K 128 Query: 816 YTIQEDELVNRLAVLMDHDRVVEKQLLEIE-HENKELQKKNQI---LLEENQNLQISLSD 871 ++ D L ++ L D ++ ++Q E E +NKE+++ + L ++N+ L D Sbjct: 129 LNLEIDNLKQQIQNLNDQLKLQQQQFDEKEKQKNKEIEELKLLHVQLEKQNETLTNEFKD 188 Query: 872 MQQHYNALVEKANRTDLA-ESESTKYQTQLRDLESN-LKRITHEH-QTLIVQKKKEIEDL 928 + +E L + E+ + ++L+D E+ LK I +E Q L +Q KE E L Sbjct: 189 NETKMLQEIEHQKLQQLQFQRENEQLMSELKDRENKMLKEIENEKLQNLEIQ--KENERL 246 Query: 929 EIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLEL 988 EF + ++D + N+K ++N + + + Q E + LN+ ++ L K ++ Sbjct: 247 RNEFKDKEIKLLQD--IENQK-QQNQQLILGKDMQGNELLQIQQKLNLEIDNL-KQQIQN 302 Query: 989 IDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYES 1048 ++ ++ QQ Q + +Q EI +L L Q + + L + + + M+ D + Sbjct: 303 LNDQLKLQQQQFDEKEKQKNKEIEELKLLHVQLELQNETLTNEFKDKET---KMILDIDH 359 Query: 1049 KLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPK 1108 Q K E Q K L+ + LQ ++ D +I +L + + I Sbjct: 360 LTLQLQLKDTKGNELFQTQQKLNLELENIQLSLQQQQQQHDVKINDLVQQQDQLNKEITS 419 Query: 1109 TEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTEL 1168 + + S + ++ NN D ++++ +E I + LQ+ + + + Sbjct: 420 YK-QLTSQKEDQINQLTNNND---------ELSVQIKGKENEINQ---LQQNLSVITNDY 466 Query: 1169 QECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTEN----DNLLSTVAELRSSI 1224 Q+ + L E + N+ I ++ + EQL E+ DN L+ + S + Sbjct: 467 QKSLKENENLTKEKLEYEAQLLENKNLIQSMQHEKEQLQNEHQLNKDNQLNDLQTQISQL 526 Query: 1225 SSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETN 1284 V + +IA Q+L Q Q E VQ+ +QL +Q + +E+ N Sbjct: 527 QQTVTSQQSQIATDKDQNLIQ-----QNKLQEQNVQI-------QQLTVQIQ-NMEEQRN 573 Query: 1285 KIVTMEQVTSLQN-KLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXX 1343 + Q+ QN K++ L N Q + I + +R I+ K++ Sbjct: 574 EFKLNNQI--FQNLKIKYVNNKLHNNQYPFKKQIKNYKSIR-PIQSSKISEIQALQSAHQ 630 Query: 1344 XXXXXXXDLRTENQSYKQMQEQSILNIN--EENAQLKKSS----XXXXXXXXXXXXRVND 1397 L EN S++ +Q + IN +E +++K + ++N+ Sbjct: 631 DLNIANNKLIEENNSFQINHDQIAIEINNLQEQCRIEKETNQKISEQNQQLSSQIEQLNE 690 Query: 1398 AEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDE---FENVRQQLVEYEKRIEDLTYE 1454 K+++ QLE+ + + + L Q +E +N ++L K +E+ ++ Sbjct: 691 EINKLVKERQQLEVTQKQDHNNQQDELNQLNQIQEEKVNLQNYNEKLENTNKHLEEQIFQ 750 Query: 1455 KESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEE 1514 + + + E +++ +E +L+++ N + + +N E K + E Sbjct: 751 LQQQSQAQNTLLEEKEQLINSLKMANEQIESQLLQDQNKQQEKDECINSINLENKKLINE 810 Query: 1515 EVAKTNEMQTALENQEIEIVT-LNDEIT---NLQNMVRASSSKIQKHVSFASDTKQGRDE 1570 + + N + + ++E LN ++T LQ V + KIQ++ + + +Q +E Sbjct: 811 KELEQNSFEEHNKQDKLEFENQLNQDVTLIAQLQEEVNQQNHKIQQYENNEKNYQQQIEE 870 Query: 1571 QLDNTMNKE 1579 ++ N E Sbjct: 871 LKEHIQNLE 879 Score = 109 bits (261), Expect = 8e-22 Identities = 195/977 (19%), Positives = 418/977 (42%), Gaps = 116/977 (11%) Query: 212 EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271 E K Q + Q + +E KD + ++LK+IE++ ++ +++ N+ L R E + Sbjct: 198 EHQKLQQLQFQRENEQLMSELKDRENKMLKEIENEKLQNLEIQKENERL---RNEFKDKE 254 Query: 272 SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEE-KGSLEIAN---------- 320 KL Q++E + ++ + EI+ K ++ N Sbjct: 255 IKLLQDIENQKQQNQQLILGKDMQGNELLQIQQKLNLEIDNLKQQIQNLNDQLKLQQQQF 314 Query: 321 ---MTELTKKIELLEHLNCQIRQTNKELENKLATMGTE--------SKAVSSPSKKGSPL 369 + K+IE L+ L+ Q+ N+ L N+ T+ + + KG+ L Sbjct: 315 DEKEKQKNKEIEELKLLHVQLELQNETLTNEFKDKETKMILDIDHLTLQLQLKDTKGNEL 374 Query: 370 ISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVIS 429 + N ++ QLS + Q D KIN L LNK++ + + S Sbjct: 375 FQTQQKLN----LELENIQLSLQQQQQQHDVKIND-----LVQQQDQLNKEITSYKQLTS 425 Query: 430 EKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQL-KQE 488 +K+ I + E Q + S+I T D + K E L K++ Sbjct: 426 QKEDQINQLTNNNDELSVQIKGKENEINQLQQNLSVI-----TNDYQKSLKENENLTKEK 480 Query: 489 LNDEIKDVNVKDLIEKLKSAEEQI---------TQLNDEIDAANKNMIKVKSNHKLKLKQ 539 L E + + K+LI+ ++ +EQ+ QLND ++ V S Sbjct: 481 LEYEAQLLENKNLIQSMQHEKEQLQNEHQLNKDNQLNDLQTQISQLQQTVTSQQSQIATD 540 Query: 540 MQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDV- 598 + + +K+ + N +I +LT ++ ++ ++ E + Q + Y + ++ + Sbjct: 541 KDQNLIQQNKLQEQNVQIQQLTVQIQNMEEQRNEFKLNNQIFQNLKIKYVNNKLHNNQYP 600 Query: 599 YKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADIS---QLQSDQV 655 +KK I+ K+I ++S K +Q L Q + +KL + + Q+ DQ+ Sbjct: 601 FKKQIK-------NYKSIRPIQSSKISEIQALQSAHQDLNIANNKLIEENNSFQINHDQI 653 Query: 656 CSEIKSVH------------LEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDK 703 EI ++ + EQ LS+ ++L I L +++QL T K N++ Sbjct: 654 AIEINNLQEQCRIEKETNQKISEQNQQLSSQIEQLNEEINKLVKERQQLEVTQKQDHNNQ 713 Query: 704 EDIMNKLQNYIQENMDLTDKLEKM--SAEKISELLAKINHEEQSKIQTQFGIDAKIQERD 761 +D +N+L +E ++L + EK+ + + + E + ++ + Q++ + I Sbjct: 714 QDELNQLNQIQEEKVNLQNYNEKLENTNKHLEEQIFQLQQQSQAQNTLLEEKEQLINSLK 773 Query: 762 LYIENIESELSKYKSRICRLEESIAV--MEDRRYSLERKADQLGSYLQEKQKAYSEYTIQ 819 + E IES+L + +++ +E I +E+++ E++ +Q S+ + ++ E+ Q Sbjct: 774 MANEQIESQLLQDQNKQQEKDECINSINLENKKLINEKELEQ-NSFEEHNKQDKLEFENQ 832 Query: 820 EDELVNRLAVLMD--------------HDRVVEKQLLEI-EH-----------EN--KEL 851 ++ V +A L + +++ ++Q+ E+ EH EN E Sbjct: 833 LNQDVTLIAQLQEEVNQQNHKIQQYENNEKNYQQQIEELKEHIQNLEDFSQVSENHISEQ 892 Query: 852 QKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRIT 911 Q+K Q L++E + L++ + Q ++ ++ + L +ST QT L + L++ Sbjct: 893 QEKEQQLIKELEALKLEYEHLSQQNSSFKDQVEQFQLQNEQSTHKQTLLENEIKELQQQQ 952 Query: 912 HEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEK--YEKNIEYVTQLEAQLQEYKN 969 + Q I Q +++I L+IE + +++ +K EK I++ L + Sbjct: 953 TDLQNNIHQYEEKINLLQIEREQDQTKLMEAEEISKQKTELEKQIKHQNDAIQNLCQQVG 1012 Query: 970 NIENLNMNVEELNKMNLELIDKHVQKQQTQSP-DYTEQYINEINKLNALLKQKDEEI--- 1025 +E+ + N E + ++I + + ++ +Q I + + AL+K + E++ Sbjct: 1013 LLEDEHPN-EYIATQKAKMIQQQKDIENLKNDIKNLQQEIKKYQEKEALIKIQKEKLERK 1071 Query: 1026 -IALNQKINNAQVSYMSMVSDYESKLA---QFTTKLENMEEEMQRVSKQLLDSKQHNEEL 1081 + +++N Q + ++ SK ++ K++++E ++ QL+ Q +E Sbjct: 1072 YLEQISELSNHQDEMFEQIKEWRSKALMSDEYLKKIKDLEMTLKFKQDQLVSYSQKIQEQ 1131 Query: 1082 QILVREQDDQIKELKET 1098 + + + + +++ELK+T Sbjct: 1132 SVQIDQLELKVQELKQT 1148 Score = 84.6 bits (200), Expect = 2e-14 Identities = 141/733 (19%), Positives = 304/733 (41%), Gaps = 51/733 (6%) Query: 858 LLEENQNLQISLSDMQQHYNALVEKANRTDLAE-SESTKYQTQLRDLESNLKRITHEHQT 916 +L+E ++ ++ Q+ + + ++ +E + Q Q DL+ +RIT+E + Sbjct: 1 MLKEIEHEKLQYIQQQKENEKFINEFKGKEIQMLNEIEQGQQQNLDLQKENERITNEFKD 60 Query: 917 LIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNM 976 + KEIE +++++ E ++++++E +K + + +E Q Q+ + I +M Sbjct: 61 RETKMLKEIEQVKLQY---AELQKENERLISEFKDKETKLLQDIENQKQQNQQLILGKDM 117 Query: 977 NVEEL----NKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKI 1032 EL K+NLE ID KQQ Q+ +N+ KL +Q DE+ N++I Sbjct: 118 QGNELLQIQQKLNLE-IDN--LKQQIQN-------LNDQLKLQQ--QQFDEKEKQKNKEI 165 Query: 1033 NNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQ- 1091 ++ ++ + E+ +F M +E++ Q L ++ NE+L +++++++ Sbjct: 166 EELKLLHVQLEKQNETLTNEFKDNETKMLQEIEHQKLQQLQFQRENEQLMSELKDRENKM 225 Query: 1092 IKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFI 1151 +KE++ KL + I K + + + +++ K + E + Sbjct: 226 LKEIENEKLQ-NLEIQKENERLRNEFKDKEIKLLQDIENQKQQNQQLILG-KDMQGNELL 283 Query: 1152 QERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTEND 1211 Q + L + L ++Q QL+ + + ++I +LK QL +N+ Sbjct: 284 QIQQKLNLEIDNLKQQIQNLND---QLKLQQQQFDEKEKQKNKEIEELKLLHVQLELQNE 340 Query: 1212 NLLSTVAELRSSISSAVDQ--RGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYE 1269 L + + + + +D ++ + L Q + +++ L + +++ Sbjct: 341 TLTNEFKDKETKMILDIDHLTLQLQLKDTKGNELFQTQQKLNLELENIQLSLQQQQQQHD 400 Query: 1270 -QLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIE 1328 ++ D VQ Q++ NK ++TS + KE+ + L ++ QI+ +EI Sbjct: 401 VKINDLVQQ--QDQLNK-----EITSYKQLTSQKEDQINQLTNNNDELSVQIKGKENEI- 452 Query: 1329 DEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXX 1388 ++ +L E Y + Q + N N + + Sbjct: 453 NQLQQNLSVITNDYQKSLKENENLTKEKLEY---EAQLLENKNLIQSMQHEKEQLQNEHQ 509 Query: 1389 XXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRI 1448 ++ND + ++ +L + + S+I + I + ++ ++Q V+ + Sbjct: 510 LNKDNQLNDLQTQISQLQQTVTSQQSQIATDKDQNLIQQNKLQEQNVQIQQLTVQIQNME 569 Query: 1449 EDLTYEKESELAI--LRLKMHENANHYETMQKESEIERVKLIEEL-NVKITESVSLNKQV 1505 E K + L++K N H + +I+ K I + + KI+E +L Sbjct: 570 EQRNEFKLNNQIFQNLKIKYVNNKLHNNQYPFKKQIKNYKSIRPIQSSKISEIQALQSAH 629 Query: 1506 AELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTK 1565 +LN A + + + N Q + + +I I EI NLQ R QK +S + Sbjct: 630 QDLNIANNKLIEENNSFQ--INHDQIAI-----EINNLQEQCRIEKETNQK-ISEQNQQL 681 Query: 1566 QGRDEQLDNTMNK 1578 + EQL+ +NK Sbjct: 682 SSQIEQLNEEINK 694 >UniRef50_Q6BUQ9 Cluster: Similar to sp|P25386 Saccharomyces cerevisiae YDL058w USO1; n=1; Debaryomyces hansenii|Rep: Similar to sp|P25386 Saccharomyces cerevisiae YDL058w USO1 - Debaryomyces hansenii (Yeast) (Torulaspora hansenii) Length = 2042 Score = 145 bits (352), Expect = 8e-33 Identities = 239/1163 (20%), Positives = 498/1163 (42%), Gaps = 82/1163 (7%) Query: 483 EQLKQELNDEIKDVNVK--DLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQM 540 EQ +Q+ D I ++ + L ++ K ++ I ++D+ + + + +++++ Sbjct: 869 EQARQKAEDGINKMSRELFHLSKQKKESDSNIKSHEKKVDSLKLEIANITKTFEARIEKL 928 Query: 541 QKTIDNFS-KVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQL---HLVDY--DSGRMI 594 QK D F KV D NK+I H +K E++E+ +++ HL+D + Sbjct: 929 QKANDLFKEKVEDLNKKISESVSYNEHSDKKSREMKEKLDDVEATNEHLMDKLRSAASAF 988 Query: 595 ESDVYKKMIEMENLAETRLKAISLLESQKFDLVQ-ELHILQQKYDEVEDKLADISQLQSD 653 + Y K + + + +++ S ++ +F+ +Q E +L+++ +++ ++ S Sbjct: 989 QEMKYAKTSSDKEIEKYKIEIKS--KNDEFNSLQLEFTLLKEEKEKINEEFESFKVKSSA 1046 Query: 654 QVCSEIKSVH-LEEQIDALSASKKELALVIENLK--LDKE-QLYGTIKDLENDK--EDIM 707 +V S++ L+ D+L ++ ++ E LK L +E + Y +K +E DK E + Sbjct: 1047 EVGKLNSSINDLKSAKDSLDSNHSTISNEFEELKEKLSQESKRYSNLK-IEYDKLLESLK 1105 Query: 708 NKLQNYIQENMDLTDKLEKMSAEKISELLAKINHE-EQSKIQTQF--GIDAKIQERDLYI 764 + + ++ D+ + E A++ S +N + + SK++ + +DAK E + I Sbjct: 1106 CENEKLKKDLEDIDNSKENAEAKQKSVEEELLNFKTKHSKVREELEKSLDAKTGEYNDAI 1165 Query: 765 ENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELV 824 E ++++ S + ++ ++ L + + S E +K E+ L Sbjct: 1166 EKLKNKDISIASLKETHSKKVSELDSGHSKLSQDLEAANSRCLETEKQIKEHLESSSNLA 1225 Query: 825 NRLAVLMDHDRVVEKQLLEIEHE-NKELQKKNQILLEENQNLQISLSDMQQHYNALVEKA 883 ++++ L +E + E E NK ++ + E NQNL ++ Q+ EK Sbjct: 1226 DQISALEKVKGELEASINNAEQESNKSREEFEKEKAELNQNLTNLEAEKQK-----AEK- 1279 Query: 884 NRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDK 943 R DL + E + +L L+ L + +T + + K +I + E E Sbjct: 1280 -RLDLVQEEKAIAEKELAKLKQILDD-NSKLETEVSELKSDITKFKDEHTIINEKLSIKT 1337 Query: 944 KVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELN--KMNLELIDKHVQKQQTQSP 1001 K L+EK ++ + E++L++ +++N + V++L K +LE K ++ + Sbjct: 1338 KELSEKKDQ----IENQESKLKDLAKSLDNEKILVKDLKEKKESLETRIKELENDIAYAS 1393 Query: 1002 DYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENME 1061 + +++ + L LK ++++ LN K N ++SD+E ++ L+ Sbjct: 1394 NSSKEMQTKNENLETKLKSTEKDLSTLNSKFTNETKILKDLISDHEVSISSLKVDLDKKV 1453 Query: 1062 EEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKET----KLTFE--MNIPKTEGMIIS 1115 +E+++ L +E + +++E D+IKEL++ K E +N E + Sbjct: 1454 QEVEKERNML------SENSETVIKEYGDKIKELEKALGIAKTAHESKLNAMSKEKKLAD 1507 Query: 1116 STIEPMSDD----ANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQEC 1171 +++ ++++ N+ + L V+ E E S L E+ A+L E + Sbjct: 1508 ESLKYINNEFEIHKNDSNESTTKLTKEIESLNVKLENERKLSTSKLSEREAELKKESETL 1567 Query: 1172 YTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRS--SISSAVD 1229 QLE +L V + QLK+ LE E D L S V E++S +++ + Sbjct: 1568 KATGKQLEDEIEKLKKEKDVVSDNF-QLKN-LEFSTLEKD-LASKVEEIKSINNVTESYK 1624 Query: 1230 QRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEE-TNKIVT 1288 + +I KQ EA QK + + +L K E+L SV S+T+E TNK+ Sbjct: 1625 KESDDIKSKTKQLENDLEAA-QKFGDKTKEELDTLNQKIEEL-KSVNSNTEETWTNKLKE 1682 Query: 1289 ME--------QVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXX 1340 E Q S+ +L + + E + N+++ L+ +IE EK Sbjct: 1683 SESSYAALDEQKKSISQELSALKSSDKAASEMTKQLENELQTLKDDIE-EKSRSKKELEE 1741 Query: 1341 XXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEA 1400 +L + + K+ + I + +A+LK+ S + + Sbjct: 1742 KSTTLSSTINELENKLDAMKKELDSEKSVIEKLSAELKEHSKLSADL------KEYKEKF 1795 Query: 1401 KVLELTHQLELKDSEIYQKTH-EYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESEL 1459 + LE H+ K + H E L + D ++ ++ + +IE L E S Sbjct: 1796 EQLEKEHEQLKKKFDAEGNIHGEKMKELKSKLDSLQDDLTAAMDLKSKIESLNQELLSTK 1855 Query: 1460 AILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKT 1519 ++ + E+ Q E+ +L ++LN E++S K+ +LN E E Sbjct: 1856 TTKDDEIKKLTKDLESTQALKNNEK-ELKKDLNSS-KENISTLKE--DLNALKENETRLK 1911 Query: 1520 NEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDE--QLDNTMN 1577 +++ + N++ L ++ +N + + + +F K+ ++E L + Sbjct: 1912 QDLEISKANEDSLNKELESLKSSQKNKEKDNIDFDSQKANFLESEKKLKEEVEALKKKLK 1971 Query: 1578 KELLDAVPRAELDLAMYMLHQRD 1600 ++ VPR+ELD M ++ D Sbjct: 1972 EQSSTMVPRSELDDLMLLMSDID 1994 Score = 138 bits (333), Expect = 2e-30 Identities = 198/876 (22%), Positives = 396/876 (45%), Gaps = 85/876 (9%) Query: 479 AKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLK 538 +KV+E+L++ L+ + + N D IEKLK+ + I L + +K + ++ S H KL Sbjct: 1144 SKVREELEKSLDAKTGEYN--DAIEKLKNKDISIASLKE---THSKKVSELDSGHS-KLS 1197 Query: 539 QMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDV 598 Q + + S+ ++ K+I E +L+ +++ LE+ KG L+ + + + + Sbjct: 1198 QDLEAAN--SRCLETEKQIKEHLESSSNLADQISALEKVKGELEASINNAEQESNKSREE 1255 Query: 599 YKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQK-YDEVEDKLADISQLQSDQVCS 657 ++K N T L+A ++ DLVQE + +K +++ L D S+L+++ S Sbjct: 1256 FEKEKAELNQNLTNLEAEKQKAEKRLDLVQEEKAIAEKELAKLKQILDDNSKLETE--VS 1313 Query: 658 EIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQEN 717 E+KS + + D + ++L++ + L K+Q I++ E+ +D+ L N Sbjct: 1314 ELKS-DITKFKDEHTIINEKLSIKTKELSEKKDQ----IENQESKLKDLAKSLDNEKILV 1368 Query: 718 MDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSR 777 DL +K E + +I EL I + S + Q K + + +++ E +LS S+ Sbjct: 1369 KDLKEKKESLET-RIKELENDIAYASNSSKEMQ----TKNENLETKLKSTEKDLSTLNSK 1423 Query: 778 ICRLEESIA-VMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRV 836 + + ++ D S+ L +QE +K + + + ++ D + Sbjct: 1424 FTNETKILKDLISDHEVSISSLKVDLDKKVQEVEKERNMLSENSETVIKEYG---DKIKE 1480 Query: 837 VEKQL--LEIEHENK-ELQKKNQILLEE-----NQNLQISLSDMQQHYNALVEKANRTDL 888 +EK L + HE+K K + L +E N +I +D + L ++ ++ Sbjct: 1481 LEKALGIAKTAHESKLNAMSKEKKLADESLKYINNEFEIHKNDSNESTTKLTKEIESLNV 1540 Query: 889 AESESTKYQT-QLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLN 947 K T +L + E+ LK+ E +TL K ++ED +IE ++K V++ Sbjct: 1541 KLENERKLSTSKLSEREAELKK---ESETLKATGK-QLED-------EIEKLKKEKDVVS 1589 Query: 948 EKYE-KNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQ 1006 + ++ KN+E+ T LE L I+++N NV E K K+ T+Q Sbjct: 1590 DNFQLKNLEFST-LEKDLASKVEEIKSIN-NVTESYK-----------KESDDIKSKTKQ 1636 Query: 1007 YINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQR 1066 N++ + EE+ LNQKI + + + +KL + + ++E+ + Sbjct: 1637 LENDLEAAQKFGDKTKEELDTLNQKIEELKSVNSNTEETWTNKLKESESSYAALDEQKKS 1696 Query: 1067 VSKQLLDSKQHNEELQILVREQDDQIKELK---ETKLTFEMNIPKTEGMIISSTIEPMSD 1123 +S++L K ++ + ++ +++++ LK E K + + + + +SSTI + Sbjct: 1697 ISQELSALKSSDKAASEMTKQLENELQTLKDDIEEKSRSKKEL-EEKSTTLSSTINELE- 1754 Query: 1124 DANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQL----E 1179 N +D ++ E+ I++ S ++ +KL+ +L+E K QL E Sbjct: 1755 --NKLDAMKK---------ELDSEKSVIEKLSAELKEHSKLSADLKEYKEKFEQLEKEHE 1803 Query: 1180 TLNTELTGHDVVNQEQINQLKSKLEQLN---TENDNLLSTVAELRSSISSAVDQRGFEIA 1236 L + ++ E++ +LKSKL+ L T +L S + L + S + EI Sbjct: 1804 QLKKKFDAEGNIHGEKMKELKSKLDSLQDDLTAAMDLKSKIESLNQELLSTKTTKDDEIK 1863 Query: 1237 ELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQ 1296 +L K L +A + E EL+ L++ + L + + + + ET +E + + Sbjct: 1864 KLTKD-LESTQA-LKNNEKELKKDLNSSKENISTLKEDLNALKENETRLKQDLEISKANE 1921 Query: 1297 NKLQDKEEHLRNLQE-KYADVINQIEILRSEIEDEK 1331 + L + E L++ Q+ K D I+ + +E EK Sbjct: 1922 DSLNKELESLKSSQKNKEKDNIDFDSQKANFLESEK 1957 Score = 128 bits (309), Expect = 1e-27 Identities = 224/1028 (21%), Positives = 448/1028 (43%), Gaps = 101/1028 (9%) Query: 151 IKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATT-----------XXXXX 199 IK K++ + LQ++ +++ + +EKINE+ + + K+ A Sbjct: 1009 IKSKNDEFNSLQLEFTLLK----EEKEKINEEFESFKVKSSAEVGKLNSSINDLKSAKDS 1064 Query: 200 XXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEW-------KDEKQRLLKDIESKDVRISS 252 E+ K+++++ + + ++ E+ K E ++L KD+E D + Sbjct: 1065 LDSNHSTISNEFEELKEKLSQESKRYSNLKIEYDKLLESLKCENEKLKKDLEDIDNSKEN 1124 Query: 253 LEEANKLLEAARFEISLEHSKLAQELEQX-XXXXXXXXXXXXXLAKQSIEPSCEEKTEIE 311 E K +E +HSK+ +ELE+ L + I + ++T + Sbjct: 1125 AEAKQKSVEEELLNFKTKHSKVREELEKSLDAKTGEYNDAIEKLKNKDISIASLKETHSK 1184 Query: 312 EKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSK-KGSPLI 370 + L+ + +K + LE N + +T K+++ L + + +S+ K KG Sbjct: 1185 KVSELDSGH----SKLSQDLEAANSRCLETEKQIKEHLESSSNLADQISALEKVKGELEA 1240 Query: 371 SRKSGRNTASKMKSPWSQLSSETLNQD-TDKKINKNEIAKLEMVIQSLNKDLVDKEYVIS 429 S + ++K + + + +E LNQ+ T+ + K + K DLV +E I+ Sbjct: 1241 SINNAEQESNKSREEFEKEKAE-LNQNLTNLEAEKQKAEK--------RLDLVQEEKAIA 1291 Query: 430 EKDTXXXXXXXXXXGK-DTLIAQLQLEHQQHMEGPSLIH--VGTNTEDVNEIAKVQEQLK 486 EK+ K +T +++L+ + + + ++I+ + T++++E E + Sbjct: 1292 EKELAKLKQILDDNSKLETEVSELKSDITKFKDEHTIINEKLSIKTKELSEKKDQIENQE 1351 Query: 487 QELNDEIKDVN-----VKDLIEKLKSAEEQITQLNDEIDAA---NKNMIKVKSNHKLKLK 538 +L D K ++ VKDL EK +S E +I +L ++I A +K M N + KLK Sbjct: 1352 SKLKDLAKSLDNEKILVKDLKEKKESLETRIKELENDIAYASNSSKEMQTKNENLETKLK 1411 Query: 539 QMQKTIDNF-SKVSDSNKEI--------VRLTEELHHLSQKVAELEEEKGNLQLHLVDYD 589 +K + SK ++ K + V ++ L +KV E+E+E+ +++ + Sbjct: 1412 STEKDLSTLNSKFTNETKILKDLISDHEVSISSLKVDLDKKVQEVEKER-----NMLSEN 1466 Query: 590 SGRMIE--SDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADI 647 S +I+ D K++ + +A+T ++ S++ L E L+ +E E D Sbjct: 1467 SETVIKEYGDKIKELEKALGIAKTAHESKLNAMSKEKKLADE--SLKYINNEFEIHKND- 1523 Query: 648 SQLQSDQVCSEIKSVHLE-EQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDI 706 S + ++ EI+S++++ E LS SK L+ LK + E L T K LE++ E Sbjct: 1524 SNESTTKLTKEIESLNVKLENERKLSTSK--LSEREAELKKESETLKATGKQLEDEIEK- 1580 Query: 707 MNKLQNYIQENMDLTD----KLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDL 762 + K ++ + +N L + LEK A K+ E + IN+ +S + I +K ++ + Sbjct: 1581 LKKEKDVVSDNFQLKNLEFSTLEKDLASKVEE-IKSINNVTESYKKESDDIKSKTKQLEN 1639 Query: 763 YIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDE 822 +E + K K + L + I ++ + E + + L+E + +Y+ Q+ Sbjct: 1640 DLEAAQKFGDKTKEELDTLNQKIEELKSVNSNTE---ETWTNKLKESESSYAALDEQKKS 1696 Query: 823 LVNRLAVLMDHDRVVEKQLLEIEHE----NKELQKKNQILLEENQNLQISLSDMQQHYNA 878 + L+ L D+ + ++E+E ++++K++ E + S + + N Sbjct: 1697 ISQELSALKSSDKAASEMTKQLENELQTLKDDIEEKSRSKKELEEKSTTLSSTINELENK 1756 Query: 879 LVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIES 938 L D +S K +L++ S L E++ Q +KE E L+ +F+ E Sbjct: 1757 LDAMKKELDSEKSVIEKLSAELKE-HSKLSADLKEYKEKFEQLEKEHEQLKKKFDA--EG 1813 Query: 939 AIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQT 998 I +K + E K L A + + K+ IE+LN +EL ++ + K+ T Sbjct: 1814 NIHGEK-MKELKSKLDSLQDDLTAAM-DLKSKIESLN---QEL--LSTKTTKDDEIKKLT 1866 Query: 999 QSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLA---QFTT 1055 + + T+ N +L L E I L + +N + + + D E A Sbjct: 1867 KDLESTQALKNNEKELKKDLNSSKENISTLKEDLNALKENETRLKQDLEISKANEDSLNK 1926 Query: 1056 KLENMEEEMQRVSKQLL--DSKQHN--EELQILVREQDDQIKELKETKLTFEMNIPKTEG 1111 +LE+++ + K + DS++ N E + L E + K+LKE T + Sbjct: 1927 ELESLKSSQKNKEKDNIDFDSQKANFLESEKKLKEEVEALKKKLKEQSSTMVPRSELDDL 1986 Query: 1112 MIISSTIE 1119 M++ S I+ Sbjct: 1987 MLLMSDID 1994 Score = 124 bits (298), Expect = 3e-26 Identities = 222/1167 (19%), Positives = 500/1167 (42%), Gaps = 103/1167 (8%) Query: 484 QLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKT 543 +L +EL+ + + + EK+K++E ++ +L++EI+ N++ VK ++++ Sbjct: 747 ELYEELDTKHSLLKTQLEEEKVKASEMEM-KLHEEINKLNRDCEDVKVQLDKACNELKEL 805 Query: 544 IDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMI 603 + S VS+ T+ L + E E G L + + D+ K + Sbjct: 806 KNKHSSVSEKYSNT---TKSLQATEKSKKEFETSSGKYFKELQEALKKFGVSDDLVKSLE 862 Query: 604 E-MENLAETRLKA----------ISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQS 652 + +EN + R KA + L QK + + ++K D ++ ++A+I++ Sbjct: 863 QKLENSEQARQKAEDGINKMSRELFHLSKQKKESDSNIKSHEKKVDSLKLEIANITKTFE 922 Query: 653 DQVCSEIKSVHL-EEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQ 711 ++ K+ L +E+++ L+ E E+ ++ + D+E E +M+KL+ Sbjct: 923 ARIEKLQKANDLFKEKVEDLNKKISESVSYNEHSDKKSREMKEKLDDVEATNEHLMDKLR 982 Query: 712 NYIQENMDLTDKLEKMSAEKISE---LLAKINHEEQSKIQTQFGI----DAKIQER-DLY 763 + ++ K K S++K E + K ++E + +Q +F + KI E + + Sbjct: 983 SAASAFQEM--KYAKTSSDKEIEKYKIEIKSKNDEFNSLQLEFTLLKEEKEKINEEFESF 1040 Query: 764 IENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDEL 823 +E+ K S I L+ + ++ ++ + ++L L ++ K YS I+ D+L Sbjct: 1041 KVKSSAEVGKLNSSINDLKSAKDSLDSNHSTISNEFEELKEKLSQESKRYSNLKIEYDKL 1100 Query: 824 VNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEE-----------NQNLQISLSDM 872 + L + ++K L +I++ + + K + + EE + L+ SL Sbjct: 1101 LESLKC---ENEKLKKDLEDIDNSKENAEAKQKSVEEELLNFKTKHSKVREELEKSLDAK 1157 Query: 873 QQHYNALVEKANRTDLA-ESESTKYQTQLRDLESNLKRITHEHQ---TLIVQKKKEI-ED 927 YN +EK D++ S + ++ +L+S +++ + + + ++ +K+I E Sbjct: 1158 TGEYNDAIEKLKNKDISIASLKETHSKKVSELDSGHSKLSQDLEAANSRCLETEKQIKEH 1217 Query: 928 LEIEFNTQIE-SAIRDKK-----VLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEEL 981 LE N + SA+ K +N +++ + + E + E N+ NL ++ Sbjct: 1218 LESSSNLADQISALEKVKGELEASINNAEQESNKSREEFEKEKAELNQNLTNLEAEKQKA 1277 Query: 982 NK-MNLELIDKHVQKQQ----TQSPDYTEQYINEINKLNA-LLKQKDEEIIALNQK--IN 1033 K ++L +K + +++ Q D + E+++L + + K KDE I +N+K I Sbjct: 1278 EKRLDLVQEEKAIAEKELAKLKQILDDNSKLETEVSELKSDITKFKDEHTI-INEKLSIK 1336 Query: 1034 NAQVS-YMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQI 1092 ++S + + ESKL L+N + ++ + ++ + +EL+ + + Sbjct: 1337 TKELSEKKDQIENQESKLKDLAKSLDNEKILVKDLKEKKESLETRIKELENDIAYASNSS 1396 Query: 1093 KELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKV---QEEEE 1149 KE++ E + TE +S+ +++ + LKV ++ +E Sbjct: 1397 KEMQTKNENLETKLKSTE-KDLSTLNSKFTNETKILKDLISDHEVSISSLKVDLDKKVQE 1455 Query: 1150 FIQERSVLQEQSAKLNTELQECYTKIIQLE-TLNTELTGHDVVNQEQINQLK---SKLEQ 1205 +ER++L E S T ++E KI +LE L T H+ + K L+ Sbjct: 1456 VEKERNMLSENS---ETVIKEYGDKIKELEKALGIAKTAHESKLNAMSKEKKLADESLKY 1512 Query: 1206 LNTENDNLLSTVAELRSSISSAVDQRGFEI---AELWKQHLAQREADFQKTEHELRVQLS 1262 +N E + + E + ++ ++ ++ +L L++REA+ +K L+ Sbjct: 1513 INNEFEIHKNDSNESTTKLTKEIESLNVKLENERKLSTSKLSEREAELKKESETLKATGK 1572 Query: 1263 AFESKYEQL---LDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQ 1319 E + E+L D V + Q + + T+E+ L +K+++ + + N+ E Y + Sbjct: 1573 QLEDEIEKLKKEKDVVSDNFQLKNLEFSTLEK--DLASKVEEIKS-INNVTESYKKESDD 1629 Query: 1320 IEILRSEIEDEKVA---FXXXXXXXXXXXXXXXXDLRTENQSYKQM-------QEQSILN 1369 I+ ++E++ A F +L++ N + ++ E S Sbjct: 1630 IKSKTKQLENDLEAAQKFGDKTKEELDTLNQKIEELKSVNSNTEETWTNKLKESESSYAA 1689 Query: 1370 INEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKD---SEIYQKTHEYTIT 1426 ++E+ + + E ++ L +E K E+ +K+ + T Sbjct: 1690 LDEQKKSISQELSALKSSDKAASEMTKQLENELQTLKDDIEEKSRSKKELEEKSTTLSST 1749 Query: 1427 LTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVK 1486 + + ++ + ++++L + IE L+ E + E + L + E +E ++KE E + K Sbjct: 1750 INELENKLDAMKKELDSEKSVIEKLSAELK-EHSKLSADLKEYKEKFEQLEKEHEQLKKK 1808 Query: 1487 LIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALE--NQEI--EIVTLNDEITN 1542 E N+ + L ++ +L++++ ++++ +E NQE+ T +DEI Sbjct: 1809 FDAEGNIHGEKMKELKSKL----DSLQDDLTAAMDLKSKIESLNQELLSTKTTKDDEIKK 1864 Query: 1543 LQNMVRASSSKIQKHVSFASDTKQGRD 1569 L + ++ + D ++ Sbjct: 1865 LTKDLESTQALKNNEKELKKDLNSSKE 1891 Score = 105 bits (253), Expect = 8e-21 Identities = 146/754 (19%), Positives = 326/754 (43%), Gaps = 73/754 (9%) Query: 826 RLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANR 885 RL + HD E Q +EL K+ +L + + ++ S+M+ + + K NR Sbjct: 727 RLKRALFHDPHAEPQGHISFELYEELDTKHSLLKTQLEEEKVKASEMEMKLHEEINKLNR 786 Query: 886 T-DLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKK 944 + + + K +L++L++ ++ ++ + + E + EF T ++ + Sbjct: 787 DCEDVKVQLDKACNELKELKNKHSSVSEKYSNT-TKSLQATEKSKKEFETSSGKYFKELQ 845 Query: 945 VLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEE-LNKMNLELIDKHVQKQQTQSPDY 1003 +K+ + + V LE +L+ N E E+ +NKM+ EL H+ KQ+ +S Sbjct: 846 EALKKFGVSDDLVKSLEQKLE----NSEQARQKAEDGINKMSRELF--HLSKQKKESDSN 899 Query: 1004 TEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEE 1063 + + +++ L + + A +K+ A + V D K+++ + E+ +++ Sbjct: 900 IKSHEKKVDSLKLEIANITKTFEARIEKLQKANDLFKEKVEDLNKKISESVSYNEHSDKK 959 Query: 1064 MQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSD 1123 + + ++L D + NE L +R +E+K K + + I K I+ +D Sbjct: 960 SREMKEKLDDVEATNEHLMDKLRSAASAFQEMKYAKTSSDKEIEK-----YKIEIKSKND 1014 Query: 1124 DANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNT 1183 + N++ ++EE+E I E + K + E+ + + I L++ Sbjct: 1015 EFNSLQLEFTL---------LKEEKEKINEE--FESFKVKSSAEVGKLNSSINDLKSAKD 1063 Query: 1184 ELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHL 1243 L + + +LK KL Q + NL +L S+ ++ ++ ++ Sbjct: 1064 SLDSNHSTISNEFEELKEKLSQESKRYSNLKIEYDKLLESLKCENEKLKKDLEDI-DNSK 1122 Query: 1244 AQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKE 1303 EA + E E L F++K+ ++ + ++ S +T + KL++K+ Sbjct: 1123 ENAEAKQKSVEEE----LLNFKTKHSKVREELEKSLDAKTG------EYNDAIEKLKNKD 1172 Query: 1304 EHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQ 1363 + +L+E ++ +++++ S++ + A L TE Q + ++ Sbjct: 1173 ISIASLKETHSKKVSELDSGHSKLSQDLEA-------------ANSRCLETEKQIKEHLE 1219 Query: 1364 EQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEY 1423 S N+ ++ + L+K +N+AE + + + E + +E+ Q Sbjct: 1220 SSS--NLADQISALEKVKGELEAS-------INNAEQESNKSREEFEKEKAELNQ----- 1265 Query: 1424 TITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIE 1483 +T + + R LV+ EK I E ELA L+ + +N+ ET E + + Sbjct: 1266 NLTNLEAEKQKAEKRLDLVQEEKAI------AEKELAKLKQILDDNSK-LETEVSELKSD 1318 Query: 1484 RVKLIEELNVKITESVSL-NKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITN 1542 K +E + I E +S+ K+++E +E + +K ++ +L+N++I + L ++ + Sbjct: 1319 ITKFKDEHTI-INEKLSIKTKELSEKKDQIENQESKLKDLAKSLDNEKILVKDLKEKKES 1377 Query: 1543 LQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTM 1576 L+ ++ + I + S +S Q ++E L+ + Sbjct: 1378 LETRIKELENDI-AYASNSSKEMQTKNENLETKL 1410 Score = 83.8 bits (198), Expect = 4e-14 Identities = 168/898 (18%), Positives = 376/898 (41%), Gaps = 98/898 (10%) Query: 714 IQENMDLTDKLEKMSAE----KISELLAKINHEEQSKIQTQFGIDAKIQ--ERDLYIENI 767 + E +D L K E K SE+ K+ HEE +K+ D K+Q + ++ + Sbjct: 748 LYEELDTKHSLLKTQLEEEKVKASEMEMKL-HEEINKLNRDCE-DVKVQLDKACNELKEL 805 Query: 768 ESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRL 827 +++ S + +S+ E + E + G Y +E Q+A ++ + +D LV L Sbjct: 806 KNKHSSVSEKYSNTTKSLQATEKSKKEFETSS---GKYFKELQEALKKFGVSDD-LVKSL 861 Query: 828 AVLMDHDRV--------VEKQLLEIEHENKELQKKNQILLEENQ---NLQISLSDMQQHY 876 +++ + K E+ H +K+ ++ + + + +L++ ++++ + + Sbjct: 862 EQKLENSEQARQKAEDGINKMSRELFHLSKQKKESDSNIKSHEKKVDSLKLEIANITKTF 921 Query: 877 NALVEKANRTDLAESESTKYQTQLRDLESNLKRIT--HEHQTLIVQKKKE-IEDLEIEFN 933 A +EK + + ++ ++ DL + +EH ++ KE ++D+E Sbjct: 922 EARIEKLQKAN------DLFKEKVEDLNKKISESVSYNEHSDKKSREMKEKLDDVEATNE 975 Query: 934 TQIESAIRDKKVLNE-KYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLE--LID 990 ++ E KY K T + ++++YK I++ N +E N + LE L+ Sbjct: 976 HLMDKLRSAASAFQEMKYAK-----TSSDKEIEKYKIEIKSKN---DEFNSLQLEFTLLK 1027 Query: 991 KHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKL 1050 + +K + + + E+ KLN+ + +L+ N++ +S + + + KL Sbjct: 1028 EEKEKINEEFESFKVKSSAEVGKLNSSINDLKSAKDSLDS--NHSTIS--NEFEELKEKL 1083 Query: 1051 AQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIK--ELKETKLTFEMNIPK 1108 +Q + + N++ E ++ + L K NE+L+ + + D+ + E K+ + E+ K Sbjct: 1084 SQESKRYSNLKIEYDKLLESL---KCENEKLKKDLEDIDNSKENAEAKQKSVEEELLNFK 1140 Query: 1109 TEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTEL 1168 T+ + +E ++D LK ++ I S+ + S K++ EL Sbjct: 1141 TKHSKVREELE------KSLDAKTGEYNDAIEKLKNKD----ISIASLKETHSKKVS-EL 1189 Query: 1169 QECYTKIIQ-LETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSA 1227 ++K+ Q LE N+ E Q+K LE + D + S + +++ + ++ Sbjct: 1190 DSGHSKLSQDLEAANSRCL-------ETEKQIKEHLESSSNLADQI-SALEKVKGELEAS 1241 Query: 1228 VDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFES---KYEQLLDSVQSSTQEETN 1284 ++ +Q + +F+K + EL L+ E+ K E+ LD VQ Sbjct: 1242 INNA--------EQESNKSREEFEKEKAELNQNLTNLEAEKQKAEKRLDLVQEEKAIAEK 1293 Query: 1285 KIVTMEQVTSLQNKLQDKEEHLRNLQEKYAD---VINQ-IEILRSEIEDEKVAFXXXXXX 1340 ++ ++Q+ +KL+ + L++ K+ D +IN+ + I E+ ++K Sbjct: 1294 ELAKLKQILDDNSKLETEVSELKSDITKFKDEHTIINEKLSIKTKELSEKK----DQIEN 1349 Query: 1341 XXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEA 1400 L E K ++E+ ++ +L+ + + E Sbjct: 1350 QESKLKDLAKSLDNEKILVKDLKEKKE-SLETRIKELENDIAYASNSSKEMQTKNENLET 1408 Query: 1401 KVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELA 1460 K+ L +S+ T+E I +D ++ V+ +K+++++ E+ Sbjct: 1409 KLKSTEKDLSTLNSKF---TNETKILKDLISDHEVSISSLKVDLDKKVQEVEKERNMLSE 1465 Query: 1461 ILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTN 1520 + E + + ++K I + +LN E ++ + +N E +N Sbjct: 1466 NSETVIKEYGDKIKELEKALGIAKTAHESKLNAMSKEKKLADESLKYINNEFEIHKNDSN 1525 Query: 1521 EMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNK 1578 E T L EI +LN ++ N + + + S+ + + S+T + +QL++ + K Sbjct: 1526 ESTTKLTK---EIESLNVKLENERKLSTSKLSEREAELKKESETLKATGKQLEDEIEK 1580 Score = 71.7 bits (168), Expect = 2e-10 Identities = 138/668 (20%), Positives = 269/668 (40%), Gaps = 59/668 (8%) Query: 143 DVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXX 202 D+ + SN+ KE L+ K+K E + L K + +I++ + Sbjct: 1388 DIAYASNSSKEMQTKNENLETKLKSTEKDLSTLNSKFTNETKILK---DLISDHEVSISS 1444 Query: 203 XXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEA 262 ++ +++ + EN + E+ D+ +K++E K + I+ +K L A Sbjct: 1445 LKVDLDKKVQEVEKERNMLSENSETVIKEYGDK----IKELE-KALGIAKTAHESK-LNA 1498 Query: 263 ARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMT 322 E L L + L K+ IE S K E E K L + ++ Sbjct: 1499 MSKEKKLADESLKYINNEFEIHKNDSNESTTKLTKE-IE-SLNVKLENERK--LSTSKLS 1554 Query: 323 ELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVS----------SPSKK--GSPLI 370 E ++ EL + ++ T K+LE+++ + E VS S +K S + Sbjct: 1555 E--REAELKKESE-TLKATGKQLEDEIEKLKKEKDVVSDNFQLKNLEFSTLEKDLASKVE 1611 Query: 371 SRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISE 430 KS N K + S+T + D + + K + + +LN+ + + + V S Sbjct: 1612 EIKSINNVTESYKKESDDIKSKTKQLENDLEAAQKFGDKTKEELDTLNQKIEELKSVNSN 1671 Query: 431 KDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELN 490 + K++ + L+ Q+ L + ++ + +E+ K E Q L Sbjct: 1672 TEETWTNKL-----KESESSYAALDEQKKSISQELSALKSSDKAASEMTKQLENELQTLK 1726 Query: 491 DEI--KDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFS 548 D+I K + K+L EK + I +L +++DA K + KS Sbjct: 1727 DDIEEKSRSKKELEEKSTTLSSTINELENKLDAMKKELDSEKS--------------VIE 1772 Query: 549 KVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENL 608 K+S KE +L+ +L +K +LE+E L+ +D+ I + K++ + Sbjct: 1773 KLSAELKEHSKLSADLKEYKEKFEQLEKEHEQLK---KKFDAEGNIHGEKMKELKSKLDS 1829 Query: 609 AETRLKAISLLESQKFDLVQE-LHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQ 667 + L A L+S+ L QE L K DE++ D+ Q+ + + L Sbjct: 1830 LQDDLTAAMDLKSKIESLNQELLSTKTTKDDEIKKLTKDLESTQALKNNEKELKKDLNSS 1889 Query: 668 IDALSASKKELALVIEN---LKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKL 724 + +S K++L + EN LK D E L + E + + +N ++N+D + Sbjct: 1890 KENISTLKEDLNALKENETRLKQDLEISKANEDSLNKELESLKSSQKNKEKDNIDFDSQK 1949 Query: 725 EKM--SAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLE 782 S +K+ E + + + + + T +++ + L + +I+ KYK ++ L Sbjct: 1950 ANFLESEKKLKEEVEALKKKLKEQSSTMVP-RSELDDLMLLMSDIDEHNKKYKKQLKALG 2008 Query: 783 ESIAVMED 790 + I+ E+ Sbjct: 2009 QDISSDEE 2016 >UniRef50_UPI000150A61D Cluster: hypothetical protein TTHERM_00370670; n=1; Tetrahymena thermophila SB210|Rep: hypothetical protein TTHERM_00370670 - Tetrahymena thermophila SB210 Length = 1534 Score = 144 bits (350), Expect = 1e-32 Identities = 272/1358 (20%), Positives = 571/1358 (42%), Gaps = 118/1358 (8%) Query: 91 SESLANTLKQKEI-LMEKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSN 149 S+ + L++ ++ + K Q + ++ + I R Q + L + Sbjct: 196 SKQMYEALQKAQVEIKNKESQMNQFIEQQRSEIKRSYDQEIQIFKETILKQEQQINSLQD 255 Query: 150 -TIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXX 208 + K+ +N + + ++ ++ T + LQ+ INEK+ +I + T Sbjct: 256 LSAKKNENETNRFEERVALLTTELERLQQIINEKNSMISKLEEKTAMFTQEIERLKLM-- 313 Query: 209 XXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEIS 268 ++ K Q+ E A+ + + Q +++ K V+ +S +E K E Sbjct: 314 ---QNEKNQVNLKLEEKCAIFTQEINRLQMIIQS-NQKQVQEASSQELQKYEERVYI--- 366 Query: 269 LEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKI 328 LE KL + Q + + E TEI+ + + + +++ Sbjct: 367 LEQEKLT--IIQDVHKLAEESQRLNEINSKLEEKVAGFSTEIDRLNMMLQSRQNQYEERV 424 Query: 329 ELL----EHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNT-ASKMK 383 L E LN I+Q E K+ + TE ++ K +I +++ N +K + Sbjct: 425 TNLTVEIERLNALIQQRTTHFEEKIVQLTTEITHLNE--SKNILIIEKQNLMNDYKNKHE 482 Query: 384 SPWSQLSSETLNQDTDKKINKNEIAKLEMVIQS---LNKDLVDKEYVISEKDTXXXXXXX 440 Q++ E + + ++A+ E ++ +KD++D+E E Sbjct: 483 DKIGQMTQEISRLNQVICQLEGQVAENEETVKRSKHTHKDVLDQERANFELINTKQNHRI 542 Query: 441 XXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKD 500 + AQ++++ Q I+ D ++ A++ L +E+ + ++ +N Sbjct: 543 IELENEKKFAQMEIQRLQER-----INDAQMERDKSQSAELA--LNREI-ENLQCIN-NS 593 Query: 501 LIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRL 560 ++++ E+I L E + + ++KS++++ ++Q T + N E + Sbjct: 594 RQREIETLHERIRVLEKE---GEQRVSEMKSHYEM-MRQSHITREVQELTIKFNSERKQF 649 Query: 561 TEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEM-------ENLAETRL 613 ++ + Q ELE NLQ+ + D R + K++ E+ +N ET + Sbjct: 650 ETQISNQFQNNRELEN---NLQIITAETDRLRQLCETKTKEIEELKQTELLQQNKMETYI 706 Query: 614 KAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSA 673 I L S D +L +LQ+ E++ + Q++ +Q E++ EQ L+ Sbjct: 707 IQIQKLNSDLQDSKNQLVVLQE---EMQRQFERQKQIELEQFERELRR-DFSEQYGQLNY 762 Query: 674 SKKELALVIENLKLD---KEQLYGTIKDLENDK--ED--IMNKLQNYI----QENMDLTD 722 ++++L E + + + IKD +N+K ED ++ + + I QE L Sbjct: 763 KLQDMSLKYEESLVAYVLQSTEFERIKD-QNEKLWEDNCVLQQKEEQIKIEFQEEFTLYK 821 Query: 723 -KLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRL 781 ++E+ + EK+ L +I +E+ Q Q+ + Q+ +L+ N ++E+++Y++ + Sbjct: 822 VEIERANREKLEIELKEI-YEKIEFQQQQYNNELNKQQTELH--NQQNEINRYQNELNAA 878 Query: 782 EESIAVMEDRRYSLERKADQLGS-------YLQEKQKAYSEYTIQEDELVNRLAVLMDHD 834 E I + D + LE K L + +QEK K S+ ++ + L Sbjct: 879 LEQIKELHDNKDELENKIVMLSTENNRLVFMIQEKDKKMSQLEVEINHLRETDNTQQSEL 938 Query: 835 RVVEKQLLEIEHENKELQKKNQILLEENQNLQI-------SLSDMQQHYNALVE----KA 883 Q E++ +EL+ K +L EN L +S + N L E + Sbjct: 939 NAALLQRKELQDNIQELENKIVMLSTENNRLVFMIQEKDKKISQQEVEINHLRETDNTQQ 998 Query: 884 NRTDLAESESTKYQTQLRDLESNLKRITHEHQTL--IVQKK-KEIEDLEIEFNTQIESAI 940 N + A + + Q +++LE+ + ++ E+ L I+Q+K K++ E+E N E AI Sbjct: 999 NELNAALLQRKELQDNIQELENKIVMLSTENNRLAFIIQEKDKKLSQQEVEINNLREKAI 1058 Query: 941 R-DKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQ 999 + + K+ + K I+ Q + ++EY +IE LN +++LN+ E+ ++ Q+ Sbjct: 1059 QLEMKIKENESLKQIQ--VQQQCAIEEYVQHIEKLNSQIDQLNRQIQEIQNQFFIDQEEL 1116 Query: 1000 SPDYTEQYINEINKLNALLK-QKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLE 1058 + Q +E+ +L LK Q ++++ ALN + + Y + + D K T +LE Sbjct: 1117 HRQHEFQRQSELEQLERRLKGQFEQQLSALNDTFTDLEDKYQNTLVDVVLK----TAELE 1172 Query: 1059 NMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTE-GMIISST 1117 M E ++ + + D + E++I ++ K+ E + +++ + + + + Sbjct: 1173 RMNELNNKLQQDISDLLTNQNEMEIKFEQEFTVYKQTAEREKQQKVDSERKQIQEKLEAQ 1232 Query: 1118 IEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQ 1177 + + + N L+ EE+ + +++ ++S KL + +++ +I Sbjct: 1233 QQQYNQEINRKQQELKYALEQTRNLE-SNVEEYEKRVTIITQESNKLLSIVEDRENRIRD 1291 Query: 1178 LETLNTELTGHDVVNQ-EQINQ----LKSKLEQLNTENDNLLSTVAELRSSISSAVDQRG 1232 LET + G NQ Q+ Q L+ K+E L +N L++ E + Q Sbjct: 1292 LETELNNIRGKS--NQISQLKQAELTLQHKIEILQLQNQKLMNDYQECQRQSLEMQIQLS 1349 Query: 1233 FEIAELWKQHLAQREADFQKTEHE----LRVQLSAFESKYEQLLDSVQSSTQE-----ET 1283 + E + + Q E DF+K +E L+ + + SKY++ L ++ T E + Sbjct: 1350 QKFEEQKRVEMEQFEIDFKKDFNEKYEILQKEFNKLFSKYQECLINIVLITAELEKIKDQ 1409 Query: 1284 NKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXX 1343 N+ + + +T Q + Q +EE E + ++E EI +K+ + Sbjct: 1410 NEKLWEDNMTLQQREGQFQEEFTAYKMEVEKNCSEKLESELKEIY-QKIEYQQQQYCQQI 1468 Query: 1344 XXXXXXXDLRTENQSYKQM----QEQSILNINEENAQL 1377 + +N +Y Q QE I+ ++ EN +L Sbjct: 1469 NVLQQDLNQANDNTNYLQSLIKEQENKIVLLSTENQRL 1506 Score = 115 bits (276), Expect = 1e-23 Identities = 237/1169 (20%), Positives = 482/1169 (41%), Gaps = 92/1169 (7%) Query: 330 LLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQL 389 +L H ++ +NKEL N+L SK + +K I +N S+M Q Sbjct: 170 VLAHQYEELMASNKELRNQLNQERETSKQMYEALQKAQVEI-----KNKESQMNQFIEQQ 224 Query: 390 SSETLNQ-DTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTL 448 SE D + +I K I K E I SL +DL K+ +E +T + Sbjct: 225 RSEIKRSYDQEIQIFKETILKQEQQINSL-QDLSAKK---NENETNRFE-------ERVA 273 Query: 449 IAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSA 508 + +LE Q + + E + E+LK N++ VN+K L EK Sbjct: 274 LLTTELERLQQIINEKNSMISKLEEKTAMFTQEIERLKLMQNEK-NQVNLK-LEEKCAIF 331 Query: 509 EEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDN--FSKVSDSNK---EIVRLTEE 563 ++I +L I + K + + S K ++ ++ + + D +K E RL E Sbjct: 332 TQEINRLQMIIQSNQKQVQEASSQELQKYEERVYILEQEKLTIIQDVHKLAEESQRLNEI 391 Query: 564 LHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQK 623 L +KVA E L + L + E V +E+E L + + E + Sbjct: 392 NSKLEEKVAGFSTEIDRLNMMLQSRQN--QYEERVTNLTVEIERLNALIQQRTTHFEEKI 449 Query: 624 FDLVQEL-HILQQK---YDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELA 679 L E+ H+ + K E ++ + D D++ + + Q+ + + ++A Sbjct: 450 VQLTTEITHLNESKNILIIEKQNLMNDYKNKHEDKIGQMTQEISRLNQV--ICQLEGQVA 507 Query: 680 LVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKI 739 E +K K + + D E +++N QN+ ++ K +M +++ E +I Sbjct: 508 ENEETVKRSKHT-HKDVLDQERANFELINTKQNHRIIELENEKKFAQMEIQRLQE---RI 563 Query: 740 NHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKA 799 N + + ++Q A +E IEN++ + + I L E I V+E E++ Sbjct: 564 NDAQMERDKSQSAELALNRE----IENLQCINNSRQREIETLHERIRVLEKEG---EQRV 616 Query: 800 DQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRV-VEKQLLEIEHENKELQKKNQIL 858 ++ S+ + ++++ +QE L + + +R E Q+ N+EL+ QI+ Sbjct: 617 SEMKSHYEMMRQSHITREVQE------LTIKFNSERKQFETQISNQFQNNRELENNLQII 670 Query: 859 LEENQNLQISLSDMQQHYNALVEKANRTDLAESESTK-YQTQLRDLESNLKRITHEHQTL 917 E L+ + + +E+ +T+L + + Y Q++ L S+L+ ++ L Sbjct: 671 TAETDRLR----QLCETKTKEIEELKQTELLQQNKMETYIIQIQKLNSDLQDSKNQLVVL 726 Query: 918 IVQKKKEIE---DLEIE-FNTQIESAIRDKK-VLNEKYEK-NIEYVTQLEAQLQEYKNNI 971 + +++ E +E+E F ++ ++ LN K + +++Y L A + + Sbjct: 727 QEEMQRQFERQKQIELEQFERELRRDFSEQYGQLNYKLQDMSLKYEESLVAYVLQ-STEF 785 Query: 972 ENLNMNVEELNKMNLELIDKHVQKQQTQSPDYT--EQYINEIN--KLNALLKQKDEEIIA 1027 E + E+L + N L K Q + ++T + I N KL LK+ E+I Sbjct: 786 ERIKDQNEKLWEDNCVLQQKEEQIKIEFQEEFTLYKVEIERANREKLEIELKEIYEKIEF 845 Query: 1028 LNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRV--SKQLLDSK-----QHNEE 1080 Q+ NN + + + ++++ ++ +L E+++ + +K L++K N Sbjct: 846 QQQQYNNELNKQQTELHNQQNEINRYQNELNAALEQIKELHDNKDELENKIVMLSTENNR 905 Query: 1081 LQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXX 1140 L +++E+D ++ +L E ++ T+ +++ + + +N+ Sbjct: 906 LVFMIQEKDKKMSQL-EVEINHLRETDNTQQSELNAALLQRKELQDNIQELENKIVMLST 964 Query: 1141 XLKVQEEEEFIQERSV-LQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQL 1199 + IQE+ + +Q ++N L+E T Q LN L + Q+ I +L Sbjct: 965 --ENNRLVFMIQEKDKKISQQEVEIN-HLRE--TDNTQQNELNAALLQRKEL-QDNIQEL 1018 Query: 1200 KSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEH--EL 1257 ++K+ L+TEN+ L + E +S Q+ EI L ++ Q E ++ E ++ Sbjct: 1019 ENKIVMLSTENNRLAFIIQEKDKKLS----QQEVEINNL-REKAIQLEMKIKENESLKQI 1073 Query: 1258 RVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSL-QNKLQDKEEHLRN--LQEKYA 1314 +VQ +Y Q ++ + S + +I ++ + Q +L + E R L++ Sbjct: 1074 QVQQQCAIEEYVQHIEKLNSQIDQLNRQIQEIQNQFFIDQEELHRQHEFQRQSELEQLER 1133 Query: 1315 DVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQ-SILNINEE 1373 + Q E S + D +L N+ ++Q+ S L N+ Sbjct: 1134 RLKGQFEQQLSALNDTFTDLEDKYQNTLVDVVLKTAELERMNELNNKLQQDISDLLTNQN 1193 Query: 1374 NAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDE 1433 ++K + +++ ++ +LE + + Q+ + L ++ Sbjct: 1194 EMEIKFEQEFTVYKQTAEREKQQKVDSERKQIQEKLEAQQQQYNQEINRKQQELKYALEQ 1253 Query: 1434 FENVRQQLVEYEKRIEDLTYEKESELAIL 1462 N+ + EYEKR+ +T E L+I+ Sbjct: 1254 TRNLESNVEEYEKRVTIITQESNKLLSIV 1282 Score = 81.8 bits (193), Expect = 1e-13 Identities = 170/812 (20%), Positives = 334/812 (41%), Gaps = 75/812 (9%) Query: 813 YSEYTIQEDELVNRLAVLMDHDRVVEKQLLE-IEHENKELQKKNQILLEENQNLQISLSD 871 Y E EL N+L + +R KQ+ E ++ E++ K + NQ ++ S+ Sbjct: 175 YEELMASNKELRNQL----NQERETSKQMYEALQKAQVEIKNKES---QMNQFIEQQRSE 227 Query: 872 MQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIE 931 +++ Y+ ++ T L K + Q+ L+ +L +E++T +++ + E+E Sbjct: 228 IKRSYDQEIQIFKETIL------KQEQQINSLQ-DLSAKKNENETNRFEERVALLTTELE 280 Query: 932 FNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEE---LNKMNLEL 988 +++ I +K + K E+ TQ +L+ +N +N+ +EE + + Sbjct: 281 ---RLQQIINEKNSMISKLEEKTAMFTQEIERLKLMQNEKNQVNLKLEEKCAIFTQEINR 337 Query: 989 IDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYES 1048 + +Q Q Q + + Q + + + +L+Q+ II K+ + S E Sbjct: 338 LQMIIQSNQKQVQEASSQELQKYEERVYILEQEKLTIIQDVHKLAEESQRLNEINSKLEE 397 Query: 1049 KLAQFTTKLENMEEEMQ----RVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEM 1104 K+A F+T+++ + +Q + +++ + E L L++++ +E K +LT E+ Sbjct: 398 KVAGFSTEIDRLNMMLQSRQNQYEERVTNLTVEIERLNALIQQRTTHFEE-KIVQLTTEI 456 Query: 1105 -NIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLK--VQEEEEFIQERSVLQEQS 1161 ++ +++ ++I M+D N + L + + E + E ++S Sbjct: 457 THLNESKNILIIEKQNLMNDYKNKHEDKIGQMTQEISRLNQVICQLEGQVAENEETVKRS 516 Query: 1162 AKLNTELQECYTKIIQLETLNT-------ELTGHDVVNQEQINQLKSKLEQLNTENDNLL 1214 + ++ + + E +NT EL Q +I +L+ ++ E D Sbjct: 517 KHTHKDVLD--QERANFELINTKQNHRIIELENEKKFAQMEIQRLQERINDAQMERDKSQ 574 Query: 1215 STVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDS 1274 S L I + E+ H +R +K E E RV S +S YE + S Sbjct: 575 SAELALNREIENLQCINNSRQREIETLH--ERIRVLEK-EGEQRV--SEMKSHYEMMRQS 629 Query: 1275 -VQSSTQEETNKIVTMEQV--TSLQNKLQDKEEHLRNLQEKYA--DVINQI-EILRSEIE 1328 + QE T K + + T + N+ Q+ E NLQ A D + Q+ E EIE Sbjct: 630 HITREVQELTIKFNSERKQFETQISNQFQNNRELENNLQIITAETDRLRQLCETKTKEIE 689 Query: 1329 DEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXX 1388 + K ++ N + + Q ++ E Q ++ Sbjct: 690 ELK----QTELLQQNKMETYIIQIQKLNSDLQDSKNQLVVLQEEMQRQFERQKQIELEQF 745 Query: 1389 XXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRI 1448 R D + +L ++L+ ++ K E + ++ EFE ++ Q EK Sbjct: 746 ERELRR--DFSEQYGQLNYKLQ----DMSLKYEESLVAYVLQSTEFERIKDQ---NEKLW 796 Query: 1449 EDLTYEKESELAILRLKMHENANHY----ETMQKES-EIERVKLIEELNVKITE-SVSLN 1502 ED ++ E I +++ E Y E +E EIE ++ E++ + + + LN Sbjct: 797 EDNCVLQQKEEQI-KIEFQEEFTLYKVEIERANREKLEIELKEIYEKIEFQQQQYNNELN 855 Query: 1503 KQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFAS 1562 KQ EL+ E NE+ ALE +I L+D L+N + S++ + V F Sbjct: 856 KQQTELHNQQNEINRYQNELNAALE----QIKELHDNKDELENKIVMLSTENNRLV-FMI 910 Query: 1563 DTKQGRDEQLDNTMNK-ELLDAVPRAELDLAM 1593 K + QL+ +N D ++EL+ A+ Sbjct: 911 QEKDKKMSQLEVEINHLRETDNTQQSELNAAL 942 Score = 78.2 bits (184), Expect = 2e-12 Identities = 171/885 (19%), Positives = 358/885 (40%), Gaps = 69/885 (7%) Query: 706 IMNKLQNYIQENMDLTDKL--EKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLY 763 + ++ + + N +L ++L E+ +++++ E L K E ++K ++Q + Q+R Sbjct: 171 LAHQYEELMASNKELRNQLNQERETSKQMYEALQKAQVEIKNK-ESQMNQFIE-QQRSEI 228 Query: 764 IENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDEL 823 + + E+ +K I + E+ I ++D S ++ ++ + + +E + + Sbjct: 229 KRSYDQEIQIFKETILKQEQQINSLQD--LSAKKNENETNRFEERVALLTTELERLQQII 286 Query: 824 VNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKA 883 + +++ + EIE +KNQ+ L+ + I ++ + ++ ++ Sbjct: 287 NEKNSMISKLEEKTAMFTQEIERLKLMQNEKNQVNLKLEEKCAIFTQEINRLQ--MIIQS 344 Query: 884 NRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDK 943 N+ + E+ S +L+ E + + E T+I K E+ + N +I S + +K Sbjct: 345 NQKQVQEASSQ----ELQKYEERVYILEQEKLTIIQDVHKLAEESQ-RLN-EINSKLEEK 398 Query: 944 KVLNEKYEKNIEYVTQ-LEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPD 1002 + I+ + L+++ +Y+ + NL + +E LN + +Q++ T + Sbjct: 399 VA---GFSTEIDRLNMMLQSRQNQYEERVTNLTVEIERLNAL--------IQQRTTHFEE 447 Query: 1003 YTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENM-- 1060 Q EI LN E L N + ++ S+L Q +LE Sbjct: 448 KIVQLTTEITHLNESKNILIIEKQNLMNDYKNKHEDKIGQMTQEISRLNQVICQLEGQVA 507 Query: 1061 --EEEMQR---VSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIIS 1115 EE ++R K +LD ++ N EL + +Q+ +I EL+ K +M I + + I Sbjct: 508 ENEETVKRSKHTHKDVLDQERANFEL--INTKQNHRIIELENEKKFAQMEIQRLQERIND 565 Query: 1116 STIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQER-SVLQEQSAKLNTELQECYTK 1174 + +E + + Q E E + ER VL+++ + +E++ Y Sbjct: 566 AQMERDKSQSAELALNREIENLQCINNSRQREIETLHERIRVLEKEGEQRVSEMKSHYEM 625 Query: 1175 IIQLETLNT--ELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRG 1232 + Q ELT ++Q S Q N E +N L + + + + Sbjct: 626 MRQSHITREVQELTIKFNSERKQFETQISNQFQNNRELENNLQIITAETDRLRQLCETKT 685 Query: 1233 FEIAELWKQHLAQRE-------------ADFQKTEHELRVQLSAFESKYEQLLDSVQSST 1279 EI EL + L Q+ +D Q ++++L V + ++E+ Sbjct: 686 KEIEELKQTELLQQNKMETYIIQIQKLNSDLQDSKNQLVVLQEEMQRQFERQKQIELEQF 745 Query: 1280 QEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXX 1339 + E + + EQ L KLQD L+ + A V+ E R + ++EK+ Sbjct: 746 ERELRRDFS-EQYGQLNYKLQDMS--LKYEESLVAYVLQSTEFERIKDQNEKL--WEDNC 800 Query: 1340 XXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAE 1399 + + E YK E++ N + +LK+ +N + Sbjct: 801 VLQQKEEQIKIEFQEEFTLYKVEIERA--NREKLEIELKEIYEKIEFQQQQYNNELNKQQ 858 Query: 1400 AKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESEL 1459 ++ +++ +E+ E L DE EN L R+ + EK+ ++ Sbjct: 859 TELHNQQNEINRYQNEL-NAALEQIKELHDNKDELENKIVMLSTENNRLVFMIQEKDKKM 917 Query: 1460 AILRLKMHENANHYETMQKESE---IERVKL---IEELNVKI----TESVSLNKQVAELN 1509 + L ++++ T Q E ++R +L I+EL KI TE+ L + E + Sbjct: 918 SQLEVEINHLRETDNTQQSELNAALLQRKELQDNIQELENKIVMLSTENNRLVFMIQEKD 977 Query: 1510 KALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKI 1554 K + ++ + N ++ Q+ E+ + LQ+ ++ +KI Sbjct: 978 KKISQQEVEINHLRETDNTQQNELNAALLQRKELQDNIQELENKI 1022 Score = 58.4 bits (135), Expect = 2e-06 Identities = 140/733 (19%), Positives = 306/733 (41%), Gaps = 88/733 (12%) Query: 846 HENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLES 905 HE K++Q N I + N I+ + +N+ + + + + ++++ Q ++ L++ Sbjct: 66 HEQKQIQANNNI--QTNTVTTITRTSRTLSFNSSLNTGS-SQIYQNQNQPIQHKVPFLQT 122 Query: 906 -----NLKRITHEHQTLIVQKKKEIEDLEI-EFNTQ--IESAIRDKKVLNEKYEKNIEYV 957 NL + TL Q+ + I N+Q I ++ VL +YE+ + Sbjct: 123 QQSSGNLANPLLQSGTLNHQRHTSCNNSTILSENSQRGIIFNAPNQGVLAHQYEELMASN 182 Query: 958 TQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINK-LNA 1016 +L QL + + + + E L K +E+ +K Q Q + EQ +EI + + Sbjct: 183 KELRNQLNQERETSKQM---YEALQKAQVEIKNKESQMNQ-----FIEQQRSEIKRSYDQ 234 Query: 1017 LLKQKDEEIIALNQKINNAQ----VSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQL- 1071 ++ E I+ Q+IN+ Q + + +E ++A TT+LE +++ + + + Sbjct: 235 EIQIFKETILKQEQQINSLQDLSAKKNENETNRFEERVALLTTELERLQQIINEKNSMIS 294 Query: 1072 -LDSK-----QHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDA 1125 L+ K Q E L+++ E++ +L+E F I + + MII S + + + + Sbjct: 295 KLEEKTAMFTQEIERLKLMQNEKNQVNLKLEEKCAIFTQEINRLQ-MIIQSNQKQVQEAS 353 Query: 1126 NNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTEL 1185 + + QE+ IQ+ L E+S +LN + K+ +TE+ Sbjct: 354 SQ----ELQKYEERVYILEQEKLTIIQDVHKLAEESQRLNEINSKLEEKVAGF---STEI 406 Query: 1186 TGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQ 1245 +++ Q + NQ + ++ L E + L + + + + + Q EI HL + Sbjct: 407 DRLNMMLQSRQNQYEERVTNLTVEIERLNALIQQRTTHFEEKIVQLTTEIT-----HLNE 461 Query: 1246 READFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVT-SLQNKLQDKEE 1304 + + L ++ +++K+E D + TQE I + QV L+ ++ + EE Sbjct: 462 SKNILIIEKQNL---MNDYKNKHE---DKIGQMTQE----ISRLNQVICQLEGQVAENEE 511 Query: 1305 HLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQE 1364 ++ + + DV++Q E+ F + + +++QE Sbjct: 512 TVKRSKHTHKDVLDQ----------ERANFELINTKQNHRIIELENEKKFAQMEIQRLQE 561 Query: 1365 QSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYT 1424 + +N + +S+ +N++ + +E H+ + +K E Sbjct: 562 R--INDAQMERDKSQSAELALNREIENLQCINNSRQREIETLHER----IRVLEKEGEQR 615 Query: 1425 ITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIER 1484 ++ + +E +RQ + E +++LT +K + +ET Q ++ + Sbjct: 616 VS--EMKSHYEMMRQSHITRE--VQELT-----------IKFNSERKQFET-QISNQFQN 659 Query: 1485 VKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQ-TALENQEIEIVTLNDEITNL 1543 + +E IT +Q+ E EE+ +T +Q +E I+I LN ++ + Sbjct: 660 NRELENNLQIITAETDRLRQLCETKTKEIEELKQTELLQQNKMETYIIQIQKLNSDLQDS 719 Query: 1544 QNMVRASSSKIQK 1556 +N + ++Q+ Sbjct: 720 KNQLVVLQEEMQR 732 >UniRef50_Q1FIV0 Cluster: Putative uncharacterized protein; n=1; Clostridium phytofermentans ISDg|Rep: Putative uncharacterized protein - Clostridium phytofermentans ISDg Length = 1361 Score = 144 bits (349), Expect = 2e-32 Identities = 290/1407 (20%), Positives = 603/1407 (42%), Gaps = 143/1407 (10%) Query: 233 KDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXX 292 K EKQR+L+ + + + ++EE +K + R + K QE++Q Sbjct: 5 KQEKQRMLEMEQGYENSLLTIEELSKSYKENRALL----EKREQEMKQLLQKVSYFQSEI 60 Query: 293 XXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATM 352 + + E K E E++ S +++ + K+++L + T KE + + Sbjct: 61 AKYNEITTEVEAYVK-EREDQISRLNSDIGDYESKLKILRLDKDSLSSTIKEKQKAYYEL 119 Query: 353 GTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINK--NEIAKL 410 + KA+ ++ + ++ N ++ + SET+ + + +I+K + L Sbjct: 120 EDKLKAIE--EERSAEKEKLEANENQIKELAKLLEE--SETIFTEKEGEISKLSENVKIL 175 Query: 411 EMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVG- 469 E+ ++ + +K +I + LI +L+LE ++ + + V Sbjct: 176 ELELEEKTSIVKNKVDLIHGLENEEKKQKEELIQNKALIEKLKLECERAKKSQEELAVQF 235 Query: 470 TNTEDVNEIAKVQ-EQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIK 528 +TE E K + LK++L + K++ L+E +K+ + ++ Q D + K +++ Sbjct: 236 KDTEAKYEQGKNEIRTLKEQLKN--KELEHNKLLENIKNLQNKLNQSVDNHENIKKELLQ 293 Query: 529 VKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDY 588 KS+ +++++K + ++ N I RL EE LEE K Q H + Sbjct: 294 SKSH----IQELEKEKEILTE--GHNDLINRLEEETGKNQGLNNSLEELK--TQSHHMKQ 345 Query: 589 DSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADIS 648 + +E + ++++ + E L E QK L++E +IL QK D + Sbjct: 346 E----LEKASSENLLKVHEIGECSNLIEELNEKQK-TLLEEFNILSQKQDSL-------- 392 Query: 649 QLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLE-------N 701 ++ +++ ++ + + E ++ + K++L +E+L+++ E L + DLE Sbjct: 393 SMEKEKLFTDKEKI--ESLLNNSNNEKEQLTKRLESLRIEAENLTSKVNDLEELLELSGE 450 Query: 702 DKEDIMNKLQNYIQENMDLTDKLEKMSAEKISEL--LAKINHEEQSKIQTQFGID-AKIQ 758 D + KL+ I+E+ L ++ + + + SE+ L + +EE+ +I+ +F + ++ Sbjct: 451 DAVQVSEKLKQAIEESNKLLEEKDTVIKQAYSEIETLKEKFNEEKLEIEDKFEHEILSLK 510 Query: 759 ERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKAD-QLGSYLQEKQKAYSEYT 817 E+ EN E E K K+ LEE I+ E + + KA+ +L Y ++ E Sbjct: 511 EQ----ENQEKEKIKVKAE-QELEEYISFAEKAKDEIRSKAELELEEYKNLVKQEKEELR 565 Query: 818 IQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYN 877 ++ ++ + L + EK+ ++ + E +E+++ + +++ +++++ + Y Sbjct: 566 VKAEQELEEYMTLAEK----EKEDIKTQAE-QEIEEYKNLAMQDKEDIKVKAEQELEEYM 620 Query: 878 ALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIE 937 L EK E + K Q + R++E E++ L +Q K ED++++ ++E Sbjct: 621 TLAEK-------EKDDIKTQAE-REIE--------EYKNLAMQDK---EDIKVKAEQELE 661 Query: 938 SAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIE----NLNMNVEELNKMNLELIDKHV 993 + L EK EK+ E Q E +L+EYK ++ L + E+ + + L +K Sbjct: 662 ----EYMTLAEK-EKD-EIRKQAELELEEYKELVKQEKVELKVKAEQELEEYIALAEKEK 715 Query: 994 QKQQTQSPDYTEQYINEINK----LNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESK 1049 + + Q+ E+Y NK + +Q+ EE IAL +K A ++ + +K Sbjct: 716 EDIRKQAEQEIEEYKKLANKEKEEIKVKAEQELEEYIALAEKEKEAIIAQSEQEFEEHAK 775 Query: 1050 LAQFTTK--LENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIP 1107 L + EN + + + +Q++ Q E L+ + ++ + E + Sbjct: 776 LVSLKQEELQENARKGQKLLEEQIVAEVQEKEHLKKQIENSREKETNFESRIRELEELLE 835 Query: 1108 KTEGMI--ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLN 1165 +EG + IS ++ ++ + +E+E+ E + E+ KL Sbjct: 836 LSEGEVSEISEKLKQSEEEKEAIKVNSESELEAYKKQTEKEKEDIKSEADRVIEEYKKLA 895 Query: 1166 TELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSIS 1225 + QE Y K+++ E E V ++++ + K EQ + DN EL Sbjct: 896 EDGQEEYKKLLEQE---KEYNKFQV--EQELEKYKKLAEQ--EKEDNKFQAAQELEKYKK 948 Query: 1226 SAVDQR---GFEIA---ELWKQHLAQREADFQ-KTEHELRVQLSAFESKYEQLLDSVQSS 1278 A ++ F+ A EL+K+ + + + + + E EL Q E + ++++ Sbjct: 949 LAEQEKENIKFQTAQELELYKKLVEKEKEEIKANAEQELEEQKKEAEQEKNEIIEQAVQE 1008 Query: 1279 TQEETNKIVTME-----QVTSLQNKLQDKE--------EHLRNLQEKYADVINQIEILRS 1325 EE K+V +E + + KL +++ E LR L E + ++ S Sbjct: 1009 L-EEIKKLVAIEAEEIIETAKKEKKLLEEQVASGFLEKEQLRELFESQNNEEKCLKSKLS 1067 Query: 1326 EIEDE---KVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSX 1382 E+ED DLR ENQ Q Q + LN+ EE + + S Sbjct: 1068 ELEDHIELTNEELINLNEKLNQSEFENKDLREENQ-LLQEQANNKLNLLEEKYEKEIDSL 1126 Query: 1383 XXXXXXXXXXXRVNDAEAKVL----ELTHQLELKDSEIYQKTHEYTITLTQRNDEFENV- 1437 + + + K+L E +QLE K +I Q+ +T++ ++ + + Sbjct: 1127 KASEQKVLDYELLINEKDKLLGQRKEQIYQLEQKLCKINQEDVTKANDITEKQEQLDRLI 1186 Query: 1438 -RQQLVEYE-KRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKI 1495 Q+++ E KR +++ + E +L + +N QK+ + KL E I Sbjct: 1187 SDQEVLSNEVKRAQEIISQLEEKLN--EGESEKNTLLSTLDQKDLIMNSAKLALEKQRDI 1244 Query: 1496 TESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQ 1555 + ++N +A+ +EE+ ++ E + + + L EIT L+ M ++K + Sbjct: 1245 SIEQTIN--LAKHKDRIEEQTKVIQQLVDNNEELQQKYIILTTEITELKKM---DAAKRE 1299 Query: 1556 KHVSFASD-TKQGRDEQLDNTMNKELL 1581 V D K+ E+ +T+N E L Sbjct: 1300 IDVGKEHDAVKEHAAEREHDTINDEKL 1326 Score = 142 bits (345), Expect = 5e-32 Identities = 274/1297 (21%), Positives = 543/1297 (41%), Gaps = 107/1297 (8%) Query: 92 ESLANTLKQKEILMEKIKQYKELS-KRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNT 150 +SL++T+K+K+ K Y EL K + R +L + S T Sbjct: 103 DSLSSTIKEKQ------KAYYELEDKLKAIEEERSAEKEKLEANENQIKELAKLLEESET 156 Query: 151 I-KEKDNALSVLQVKMKIMETTILDLQEKI----NEKDQI--IEAKNKATTXXXXXXXXX 203 I EK+ +S L +KI+E L+L+EK N+ D I +E + K Sbjct: 157 IFTEKEGEISKLSENVKILE---LELEEKTSIVKNKVDLIHGLENEEKKQKEELIQNKAL 213 Query: 204 XXXXXXXXEDTKQQMTKMQENFIAMEAEW---KDEKQRLLKDIESKDVRISSLEEANKLL 260 E K+ ++ F EA++ K+E + L + +++K++ + L E K L Sbjct: 214 IEKLKLECERAKKSQEELAVQFKDTEAKYEQGKNEIRTLKEQLKNKELEHNKLLENIKNL 273 Query: 261 EAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAK----------------QSIEPSC 304 + + H + +EL Q L + Q + S Sbjct: 274 QNKLNQSVDNHENIKKELLQSKSHIQELEKEKEILTEGHNDLINRLEEETGKNQGLNNSL 333 Query: 305 EE-KTEIEE-KGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSP 362 EE KT+ K LE A+ L K E+ E N I + N++ + L S+ S Sbjct: 334 EELKTQSHHMKQELEKASSENLLKVHEIGECSNL-IEELNEKQKTLLEEFNILSQKQDSL 392 Query: 363 SKKGSPLISRKSG-RNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDL 421 S + L + K + + + QL+ + + + +++ LE +++ +D Sbjct: 393 SMEKEKLFTDKEKIESLLNNSNNEKEQLTKRLESLRIEAENLTSKVNDLEELLELSGEDA 452 Query: 422 VDKEYVISEK-DTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAK 480 V +SEK KDT+I Q E + E + + + +EI Sbjct: 453 VQ----VSEKLKQAIEESNKLLEEKDTVIKQAYSEIETLKEKFNEEKLEIEDKFEHEILS 508 Query: 481 VQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAA---NKNMIKVKSNHKLKL 537 ++EQ QE ++IK ++L E + AE+ ++ + + KN++K + +L++ Sbjct: 509 LKEQENQE-KEKIKVKAEQELEEYISFAEKAKDEIRSKAELELEEYKNLVK-QEKEELRV 566 Query: 538 KQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQK---VAELEEEKGNLQLHLVDYDSGRMI 594 K Q+ ++ + +++ KE ++ E K + + E+ K + L +Y + Sbjct: 567 KAEQE-LEEYMTLAEKEKEDIKTQAEQEIEEYKNLAMQDKEDIKVKAEQELEEYMTLAEK 625 Query: 595 ESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQ 654 E D K E E + E + A+ E K QEL ++ +D++ ++L+ ++ Sbjct: 626 EKDDIKTQAERE-IEEYKNLAMQDKEDIKVKAEQELEEYMTLAEKEKDEIRKQAELELEE 684 Query: 655 VCSEIKSVHLEEQIDALSASKKELALVI---ENLKLDKEQLYGTIKDLEN-DKEDIMNKL 710 +K +E ++ A ++ +AL E+++ EQ K L N +KE+I K Sbjct: 685 YKELVKQEKVELKVKAEQELEEYIALAEKEKEDIRKQAEQEIEEYKKLANKEKEEIKVKA 744 Query: 711 QNYIQENMDLTDKLEKM---SAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENI 767 + ++E + L +K ++ +E+ E AK+ +Q ++Q K+ E + E Sbjct: 745 EQELEEYIALAEKEKEAIIAQSEQEFEEHAKLVSLKQEELQENARKGQKLLEEQIVAEVQ 804 Query: 768 ESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDEL-VNR 826 E E K +I E E R LE + + E + + +++ + VN Sbjct: 805 EKE--HLKKQIENSREKETNFESRIRELEELLELSEGEVSEISEKLKQSEEEKEAIKVNS 862 Query: 827 LAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNAL-----VE 881 + L + + EK+ +I+ E + ++ + L E+ Q L + ++ YN +E Sbjct: 863 ESELEAYKKQTEKEKEDIKSEADRVIEEYKKLAEDGQEEYKKLLEQEKEYNKFQVEQELE 922 Query: 882 KANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQK-------KKEIEDLEIEFNT 934 K + E E K+Q ++LE K E + + Q KK +E + E Sbjct: 923 KYKKLAEQEKEDNKFQAA-QELEKYKKLAEQEKENIKFQTAQELELYKKLVEKEKEEIKA 981 Query: 935 QIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHV- 993 E + ++K E+ EKN E + Q +L+E K + + E K +L+++ V Sbjct: 982 NAEQELEEQKKEAEQ-EKN-EIIEQAVQELEEIKKLVAIEAEEIIETAKKEKKLLEEQVA 1039 Query: 994 ----QKQQT----QSPDYTEQYI-NEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVS 1044 +K+Q +S + E+ + +++++L ++ +EE+I LN+K+N ++ + Sbjct: 1040 SGFLEKEQLRELFESQNNEEKCLKSKLSELEDHIELTNEELINLNEKLNQSEFENKDLRE 1099 Query: 1045 DYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEM 1104 + + Q KL +EE+ ++ L S+Q + ++L+ E+D + + KE E Sbjct: 1100 ENQLLQEQANNKLNLLEEKYEKEIDSLKASEQKVLDYELLINEKDKLLGQRKEQIYQLEQ 1159 Query: 1105 NIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKL 1164 + K ++ +++ +D +K + +E Q L E ++ Sbjct: 1160 KLCKINQEDVTKA-NDITEKQEQLDRLISDQEVLSNEVK-RAQEIISQLEEKLNEGESEK 1217 Query: 1165 NTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSI 1224 NT L K + + + L ++ EQ L +++ E ++ + + + Sbjct: 1218 NTLLSTLDQKDLIMNSAKLALEKQRDISIEQTINLAKHKDRIE-EQTKVIQQLVDNNEEL 1276 Query: 1225 SSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETN 1284 EI EL K A+RE D K EH+ V+ A E +++ + D E+ + Sbjct: 1277 QQKYIILTTEITELKKMDAAKREIDVGK-EHD-AVKEHAAEREHDTIND-------EKLH 1327 Query: 1285 KIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIE 1321 K + L+ KL++K++ + L+ + +++ ++E Sbjct: 1328 K-----EKQLLEMKLEEKDKKIDELETQIIELMVELE 1359 Score = 140 bits (338), Expect = 4e-31 Identities = 272/1336 (20%), Positives = 583/1336 (43%), Gaps = 145/1336 (10%) Query: 143 DVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXX 202 D LS+TIKEK A L+ K+K +E +EK+ + I+ K Sbjct: 101 DKDSLSSTIKEKQKAYYELEDKLKAIEEERSAEKEKLEANENQIKELAKLLEESETIFTE 160 Query: 203 XXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEA 262 E+ K +++E ++ K L+ +E+++ + NK L Sbjct: 161 KEGEISKLSENVKILELELEEKTSIVK-----NKVDLIHGLENEEKKQKEELIQNKAL-I 214 Query: 263 ARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLE-IANM 321 + ++ E +K +QE ++++ + K E+E LE I N+ Sbjct: 215 EKLKLECERAKKSQEELAVQFKDTEAKYEQGKNEIRTLKEQLKNK-ELEHNKLLENIKNL 273 Query: 322 -TELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSG-RNTA 379 +L + ++ E++ ++ Q+ ++ ++ + + + G N+ Sbjct: 274 QNKLNQSVDNHENIKKELLQSKSHIQELEKEKEILTEGHNDLINRLEEETGKNQGLNNSL 333 Query: 380 SKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLN---KDLVDKEYVISEKDTXXX 436 ++K+ + E ++ + +EI + +I+ LN K L+++ ++S+K Sbjct: 334 EELKTQSHHMKQELEKASSENLLKVHEIGECSNLIEELNEKQKTLLEEFNILSQK----- 388 Query: 437 XXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDV 496 +D+L + + + SL++ N ++ ++ K E L+ E + V Sbjct: 389 --------QDSLSMEKEKLFTDKEKIESLLNNSNNEKE--QLTKRLESLRIEAENLTSKV 438 Query: 497 NVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKE 556 N DL E L+ + E Q+++++ A + K+ +KQ I+ + N+E Sbjct: 439 N--DLEELLELSGEDAVQVSEKLKQAIEESNKLLEEKDTVIKQAYSEIETLKE--KFNEE 494 Query: 557 IVRLTEELHH--LSQKVAELEEE---KGNLQLHLVDYDSGRMIESDVYKKMIEMENLAET 611 + + ++ H LS K E +E+ K + L +Y S D + E+E L E Sbjct: 495 KLEIEDKFEHEILSLKEQENQEKEKIKVKAEQELEEYISFAEKAKDEIRSKAELE-LEEY 553 Query: 612 RLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDAL 671 + +L++ +K +L + ++Y + +K + + Q++Q E K++ ++++ D Sbjct: 554 K----NLVKQEKEELRVKAEQELEEYMTLAEKEKEDIKTQAEQEIEEYKNLAMQDKEDIK 609 Query: 672 SASKKEL---ALVIENLKLD-KEQLYGTIKDLEN----DKEDIMNKLQNYIQENMDLTDK 723 +++EL + E K D K Q I++ +N DKEDI K + ++E M L +K Sbjct: 610 VKAEQELEEYMTLAEKEKDDIKTQAEREIEEYKNLAMQDKEDIKVKAEQELEEYMTLAEK 669 Query: 724 LEKMSAEKISELLAKINHE--EQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRL 781 EK K +EL + E +Q K++ + + +++E E + ++ K + + Sbjct: 670 -EKDEIRKQAELELEEYKELVKQEKVELKVKAEQELEEYIALAEKEKEDIRKQAEQ--EI 726 Query: 782 EESIAVMEDRRYSLERKADQ-LGSY--LQEKQK----AYSEYTIQED-ELVN-RLAVLMD 832 EE + + ++ KA+Q L Y L EK+K A SE +E +LV+ + L + Sbjct: 727 EEYKKLANKEKEEIKVKAEQELEEYIALAEKEKEAIIAQSEQEFEEHAKLVSLKQEELQE 786 Query: 833 HDR----VVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQ-------HYNALVE 881 + R ++E+Q++ E + L+K+ + E+ N + + ++++ + + E Sbjct: 787 NARKGQKLLEEQIVAEVQEKEHLKKQIENSREKETNFESRIRELEELLELSEGEVSEISE 846 Query: 882 KANRTD--------LAESESTKYQTQL----RDLESNLKRITHEHQTLIVQKKKEIEDL- 928 K +++ +ESE Y+ Q D++S R+ E++ L ++E + L Sbjct: 847 KLKQSEEEKEAIKVNSESELEAYKKQTEKEKEDIKSEADRVIEEYKKLAEDGQEEYKKLL 906 Query: 929 --EIEFNT-QIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMN 985 E E+N Q+E + K L E+ +++ ++ Q +L++YK E N++ Sbjct: 907 EQEKEYNKFQVEQELEKYKKLAEQEKEDNKF--QAAQELEKYKKLAEQEKENIKFQTAQE 964 Query: 986 LELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSD 1045 LEL K V+K++ + EQ + E K +Q+ EII Q + + +V+ Sbjct: 965 LELYKKLVEKEKEEIKANAEQELEEQKK---EAEQEKNEII--EQAVQELE-EIKKLVAI 1018 Query: 1046 YESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMN 1105 ++ +E ++E + + +Q+ E+L+ L Q+++ K LK E + Sbjct: 1019 EAEEI------IETAKKEKKLLEEQVASGFLEKEQLRELFESQNNEEKCLKSKLSELEDH 1072 Query: 1106 IPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQER-----SVLQEQ 1160 I T +I+ + + N D ++EE + +QE+ ++L+E+ Sbjct: 1073 IELTNEELINLNEKLNQSEFENKD--------------LREENQLLQEQANNKLNLLEEK 1118 Query: 1161 SAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAEL 1220 K L+ K++ E L E +EQI QL+ KL ++N E+ + + E Sbjct: 1119 YEKEIDSLKASEQKVLDYELLINEKDKLLGQRKEQIYQLEQKLCKINQEDVTKANDITEK 1178 Query: 1221 RSSISSAVDQRGFEIAELWK--QHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSS 1278 + + + + E+ + + ++Q E + E E LS + K + +++S + + Sbjct: 1179 QEQLDRLISDQEVLSNEVKRAQEIISQLEEKLNEGESEKNTLLSTLDQK-DLIMNSAKLA 1237 Query: 1279 TQEETNKIVTMEQVTSL---QNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFX 1335 +++ + +++EQ +L +++++++ + ++ L + ++ + IL +EI + K Sbjct: 1238 LEKQRD--ISIEQTINLAKHKDRIEEQTKVIQQLVDNNEELQQKYIILTTEITELK---- 1291 Query: 1336 XXXXXXXXXXXXXXXDLRTENQSYKQ-MQEQSILNINEENAQLKKSSXXXXXXXXXXXXR 1394 D+ E+ + K+ E+ IN+E +L K + Sbjct: 1292 ------KMDAAKREIDVGKEHDAVKEHAAEREHDTINDE--KLHKEKQLLEMKLEEKDKK 1343 Query: 1395 VNDAEAKVLELTHQLE 1410 +++ E +++EL +LE Sbjct: 1344 IDELETQIIELMVELE 1359 Score = 84.2 bits (199), Expect = 3e-14 Identities = 124/601 (20%), Positives = 254/601 (42%), Gaps = 49/601 (8%) Query: 1017 LLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQ 1076 L KQ+ + ++ + Q N+ ++ + Y+ A + + M++ +Q+VS + + Sbjct: 3 LSKQEKQRMLEMEQGYENSLLTIEELSKSYKENRALLEKREQEMKQLLQKVSYFQSEIAK 62 Query: 1077 HNE---ELQILVREQDDQIKELKETKLTFE--MNIPKTEGMIISSTIEPMSDDANNVDXX 1131 +NE E++ V+E++DQI L +E + I + + +SSTI+ ++ Sbjct: 63 YNEITTEVEAYVKEREDQISRLNSDIGDYESKLKILRLDKDSLSSTIKEKQKAYYELE-- 120 Query: 1132 XXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVV 1191 LK EE ERS +E+ +++E + + ET+ TE G Sbjct: 121 --------DKLKAIEE-----ERSAEKEKLEANENQIKELAKLLEESETIFTEKEGEISK 167 Query: 1192 NQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQ 1251 E + L+ +LE+ + N + + L + ++ A + K L A + Sbjct: 168 LSENVKILELELEEKTSIVKNKVDLIHGLENEEKKQKEELIQNKALIEKLKLECERA--K 225 Query: 1252 KTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIV----TMEQVTSLQNKLQDKEEHLR 1307 K++ EL VQ E+KYEQ + +++ ++ NK + +E + +LQNKL ++ Sbjct: 226 KSQEELAVQFKDTEAKYEQGKNEIRTLKEQLKNKELEHNKLLENIKNLQNKLNQSVDNHE 285 Query: 1308 NLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSI 1367 N++++ + I+ E+E EK + N S ++++ QS Sbjct: 286 NIKKELLQSKSHIQ----ELEKEKEILTEGHNDLINRLEEETGKNQGLNNSLEELKTQS- 340 Query: 1368 LNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITL 1427 ++ +E + + + + K L + + + QK ++ Sbjct: 341 HHMKQELEKASSENLLKVHEIGECSNLIEELNEKQKTLLEEFNI----LSQKQDSLSMEK 396 Query: 1428 TQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKL 1487 + + E + L E LT ES L I + N E + + S + V++ Sbjct: 397 EKLFTDKEKIESLLNNSNNEKEQLTKRLES-LRIEAENLTSKVNDLEELLELSGEDAVQV 455 Query: 1488 IEELNVKITESVSLNKQVAELNKALEEEV----AKTNEMQTALENQ-EIEIVTLNDEITN 1542 E+L I ES L ++ + K E+ K NE + +E++ E EI++L ++ Sbjct: 456 SEKLKQAIEESNKLLEEKDTVIKQAYSEIETLKEKFNEEKLEIEDKFEHEILSLKEQENQ 515 Query: 1543 LQNMVRA-SSSKIQKHVSFASDTK-------QGRDEQLDNTMNKELLDAVPRAELDLAMY 1594 + ++ + ++++++SFA K + E+ N + +E + +AE +L Y Sbjct: 516 EKEKIKVKAEQELEEYISFAEKAKDEIRSKAELELEEYKNLVKQEKEELRVKAEQELEEY 575 Query: 1595 M 1595 M Sbjct: 576 M 576 >UniRef50_A2FVB6 Cluster: Putative uncharacterized protein; n=2; Trichomonas vaginalis G3|Rep: Putative uncharacterized protein - Trichomonas vaginalis G3 Length = 1684 Score = 144 bits (349), Expect = 2e-32 Identities = 232/1182 (19%), Positives = 497/1182 (42%), Gaps = 79/1182 (6%) Query: 92 ESLANTLKQKEILMEKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTI 151 + L + LK+K+ ++E+ ++ E + +L ++ + + Sbjct: 521 KKLNDDLKEKDKIIEENEKNNEQKVSDLKKQIEDLSKQKENENSDVLQKLDNLQKENQKL 580 Query: 152 KEKDNALSVLQVKMKIMETTILDLQ-EKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXX 210 KE++ K+K + ++ +K+ D+ + K Sbjct: 581 KEENEEKESELQKLKQENENLKNIDAQKVTYDDEKVSELQKIIEDLKKENELIQNQKETN 640 Query: 211 XEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDI---ESKDVRISSLEEANKLLEAARF-E 266 + ++ K+ E+ + K E + + D+ E ++ I L+E N +E + E Sbjct: 641 DNEKISELQKIVEDLKNENEKLKSEVNQKVTDLQKAEGENDLIKKLQEENLEIENEKDKE 700 Query: 267 ISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTK 326 IS + KL + Q ++ E + + + EIE + + + L + Sbjct: 701 ISELNEKLEKLQNQVNNLSSEKVTKDDIISSLQSEVN-DLQEEIESRKDDKQKEINSLKE 759 Query: 327 KIELLEHLNCQIRQTNKE----LENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKM 382 KIE LE+ ++ + E LE +++ + E + + ++K S I + +S+ Sbjct: 760 KIETLENEKISLQDSMNEEIHKLEEEISNLQNEKSVLETENEKLSKQIEELQEKEKSSQE 819 Query: 383 KSPWSQLSSETLNQDTDK--KINKNEIAKLEMVIQSLNKDLVD----KEYVISEKDTXXX 436 ++ +E + + K K + E KL I+ + KDL D KE + ++ + Sbjct: 820 ENEELSKQNEEMKEKLSKQDKEFEEEKEKLNAKIEKIEKDLSDGNNEKETLTNDFEDEVK 879 Query: 437 XXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTN----TEDV-----NEIAKVQEQLKQ 487 K+ I QL+ E Q E + + + +DV N+I K E L Sbjct: 880 RIEEDIDNKNKQIKQLEEEKSQLNEEMNKLQLNNEFLQKQKDVVETENNKIKKDFESLLS 939 Query: 488 ELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNF 547 LN K +K E+ + E+ E++ M K + L++++ N Sbjct: 940 SLNKPDKSEMIKKFDEEKQQELEKTKTAKSELENQIHQMSIEKQKLTINLEKLENDKLNL 999 Query: 548 SK-VSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEME 606 V+D + +T+ L L +K +L+ +L ++ + + R E + K E++ Sbjct: 1000 QNIVNDYQSKNSEMTKNLQDLQKKNFDLQNLYDDL-INKTNEQNHRN-EKSLENKDEEIK 1057 Query: 607 NLAETRLKAISLLESQKFDLV---QELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVH 663 L +T+ + S +ESQ L +++ +L+ K +++E++ + + + +++ SE++ H Sbjct: 1058 QLKDTQHELESKIESQLESLQNNEEKIKLLESKIEDLEEEKLEQNNINQNKI-SELE--H 1114 Query: 664 LEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDK 723 E++ S + E I L+ ++ TI+ L E++ + +N D Sbjct: 1115 KIEELQNNSLNNDENENKISELENQVQEYQETIEKLRKQIEELEKEKENK-------ADT 1167 Query: 724 LEKMSAEKISELLAKINHEEQSKIQTQFGIDAK-IQERDLYIENIESELSKYKSRICRLE 782 E S+ KI EL KI EE K F + + I + + + +E+S + C+LE Sbjct: 1168 SETESSTKIKELEDKI--EELEKENDLFQNEGESILDLQEEVTKLNNEISTLRQLTCKLE 1225 Query: 783 ESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLL 842 E ++D E+ L L+EK+K ++ L+VL + +++++ Sbjct: 1226 EDNKTLKDGSEEDEKLISSLRKQLKEKEKEKESENDNISQIKTNLSVLSKENDKLKREMQ 1285 Query: 843 EIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRD 902 + + +L L EN++L+ L D+++ +++K + T Sbjct: 1286 MKDDKISDLSILTSSLRTENEHLKSDL-DIKKKEIDIIKKNDET---------------- 1328 Query: 903 LESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEA 962 ++S L +I + + + K I+ L+ + + +K L + +++ E + QL+ Sbjct: 1329 VQSALDQIKNSNSS-----DKTIKSLQSQLSVCCMQKETLEKELEDMRKEDQETIAQLKQ 1383 Query: 963 QLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKD 1022 + E + I +L+ E N+M ++L K Q+Q + ++ N++N + K Sbjct: 1384 VVNELQTKI-SLSSPQREFNQMKIQL--KQKQEQIERLRQENDELQNKVNYIKEKAKNDI 1440 Query: 1023 EEIIALNQ--KINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLD---SKQH 1077 ++II Q ++ +++ + +S VSD K+ F + + + E+ + KQL +Q Sbjct: 1441 KDIIKKTQVPEVKSSEKT-LSEVSDLRRKVLMFDKENQKLTEQNNELKKQLQSISVLEQR 1499 Query: 1078 NEELQILVREQDDQIKEL-KETKLTFEMNIPKTE-GMIISSTIEPMSDDANNVDXXXXXX 1135 +E + + + KEL +E KL + KT+ T+ S ++ + Sbjct: 1500 EKEYITQISKLTKKTKELEEENKLIKKSEEDKTDIEQRYLDTVTNTSKMSHEIQTLNETI 1559 Query: 1136 XXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQ 1195 L Q +++ +QE+ +Q + + L T L ++ + N +L N + Sbjct: 1560 NTLTQKLS-QLKKQHLQEKKEMQIEVSTLKTSLDSSLKELEEERKHNMQLIKDSKTNIVK 1618 Query: 1196 INQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAE 1237 +++L+ +L +N+ +S+V+ LR+S S + Q I++ Sbjct: 1619 LSELERTHAELRNQNET-ISSVSVLRTSPVSPLRQESSIISD 1659 Score = 135 bits (327), Expect = 8e-30 Identities = 207/1039 (19%), Positives = 441/1039 (42%), Gaps = 82/1039 (7%) Query: 575 EEEKGNLQLHLVDY-DSGRMIESDVYKKMIE---MENLAETRL-KAISLLESQKFDLVQE 629 E+ +G+++ HL+ + ++ D K+IE + + E ++ A++ ++S ++L E Sbjct: 429 EQTRGDVK-HLISLLFTSLLMYKDCEDKIIENICLLLIGEEKVYNALTEMKSNSYELWNE 487 Query: 630 LHILQQKYDEVEDKLADISQ---LQSDQVCSEIKSVH--LEEQIDALSASKKELALVIEN 684 K + L ++SQ L ++V E+K ++ L+E+ + ++K + + Sbjct: 488 FEEDLIKIIMDKKPLENVSQFDNLTDEEVKKELKKLNDDLKEKDKIIEENEKNNEQKVSD 547 Query: 685 LKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQ 744 LK E L K EN+ D++ KL N +EN L ++ E+ +E + +L + + + Sbjct: 548 LKKQIEDLS---KQKENENSDVLQKLDNLQKENQKLKEENEEKESE-LQKLKQENENLKN 603 Query: 745 SKIQTQFGIDAKIQERDLYIENI--ESELSKYKSRIC---RLEESIAVMEDRRYSLERKA 799 Q D K+ E IE++ E+EL + + ++ E ++ED + E+ Sbjct: 604 IDAQKVTYDDEKVSELQKIIEDLKKENELIQNQKETNDNEKISELQKIVEDLKNENEKLK 663 Query: 800 DQLGSYLQEKQKAYSEYTIQEDELVNRLAVL-MDHDRVVEKQLLEIEHENKELQKKNQIL 858 ++ + + QKA E ++L+ +L ++ + +K++ E+ + ++LQ + L Sbjct: 664 SEVNQKVTDLQKAEGE-----NDLIKKLQEENLEIENEKDKEISELNEKLEKLQNQVNNL 718 Query: 859 LEENQNLQISLSDMQQHYNALVEKA-NRTDLAESESTKYQTQLRDLESNLKRITHEHQTL 917 E +S +Q N L E+ +R D + E + ++ LE+ + Sbjct: 719 SSEKVTKDDIISSLQSEVNDLQEEIESRKDDKQKEINSLKEKIETLENEKISLQDSMNEE 778 Query: 918 IVQKKKEIEDLEIE---FNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENL 974 I + ++EI +L+ E T+ E + + L EK + + E +L Q +E K + Sbjct: 779 IHKLEEEISNLQNEKSVLETENEKLSKQIEELQEKEKSSQEENEELSKQNEEMKEKLSKQ 838 Query: 975 NMNVEE-LNKMN--LELIDKHVQKQQTQSPDYTEQYINEINKL-------NALLKQKDEE 1024 + EE K+N +E I+K + + T + +E+ ++ N +KQ +EE Sbjct: 839 DKEFEEEKEKLNAKIEKIEKDLSDGNNEKETLTNDFEDEVKRIEEDIDNKNKQIKQLEEE 898 Query: 1025 IIALNQKINNAQVS------YMSMVSDYESKLAQ-FTTKLE--NMEEEMQRVSKQLLDSK 1075 LN+++N Q++ +V +K+ + F + L N ++ + + K + + Sbjct: 899 KSQLNEEMNKLQLNNEFLQKQKDVVETENNKIKKDFESLLSSLNKPDKSEMIKKFDEEKQ 958 Query: 1076 QHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXX 1135 Q E+ + E ++QI ++ K +N+ K E ++ + N + Sbjct: 959 QELEKTKTAKSELENQIHQMSIEKQKLTINLEKLENDKLNLQNIVNDYQSKNSEMTKNLQ 1018 Query: 1136 XXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVV---- 1191 +Q + + ++ EQ+ + L+ +I QL+ EL Sbjct: 1019 DLQKKNFDLQNLYDDLINKT--NEQNHRNEKSLENKDEEIKQLKDTQHELESKIESQLES 1076 Query: 1192 ---NQEQINQLKSKLEQLNTE----NDNLLSTVAELRSSISSAVDQR-GFEIAELWKQHL 1243 N+E+I L+SK+E L E N+ + ++EL I + + E L Sbjct: 1077 LQNNEEKIKLLESKIEDLEEEKLEQNNINQNKISELEHKIEELQNNSLNNDENENKISEL 1136 Query: 1244 AQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKL-QDK 1302 + ++Q+T +LR Q+ E + E D+ ++ + + ++ + +N L Q++ Sbjct: 1137 ENQVQEYQETIEKLRKQIEELEKEKENKADTSETESSTKIKELEDKIEELEKENDLFQNE 1196 Query: 1303 EEHLRNLQEKYADVINQIEILRS---EIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSY 1359 E + +LQE+ + N+I LR ++E++ L+ E + Sbjct: 1197 GESILDLQEEVTKLNNEISTLRQLTCKLEEDNKTLKDGSEEDEKLISSLRKQLK-EKEKE 1255 Query: 1360 KQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQK 1419 K+ + +I I + L K + +++D L + E S++ K Sbjct: 1256 KESENDNISQIKTNLSVLSKENDKLKREMQMKDDKISDLSILTSSLRTENEHLKSDLDIK 1315 Query: 1420 THEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKE 1479 E I + ++NDE ++ + +S+L++ ++ E M+KE Sbjct: 1316 KKE--IDIIKKNDETVQSALDQIKNSNSSDKTIKSLQSQLSVCCMQKETLEKELEDMRKE 1373 Query: 1480 SEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDE 1539 + E + ++++ ++ +SL+ E N +M+ L+ ++ +I L E Sbjct: 1374 DQ-ETIAQLKQVVNELQTKISLSSPQREFN-----------QMKIQLKQKQEQIERLRQE 1421 Query: 1540 ITNLQNMVRASSSKIQKHV 1558 LQN V K + + Sbjct: 1422 NDELQNKVNYIKEKAKNDI 1440 Score = 126 bits (303), Expect = 7e-27 Identities = 176/802 (21%), Positives = 361/802 (45%), Gaps = 84/802 (10%) Query: 795 LERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAV-LMDHDRVVEKQLLEIEHENKELQK 853 ++++ +L L+EK K E ++ V+ L + D + E + ++ + LQK Sbjct: 516 VKKELKKLNDDLKEKDKIIEENEKNNEQKVSDLKKQIEDLSKQKENENSDVLQKLDNLQK 575 Query: 854 KNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHE 913 +NQ L EEN+ + L ++Q E N ++ + T ++ +L+ ++ + E Sbjct: 576 ENQKLKEENEEKESELQKLKQ------ENENLKNIDAQKVTYDDEKVSELQKIIEDLKKE 629 Query: 914 HQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNI-EYVTQLEAQLQEYKNNIE 972 ++ ++Q +KE D E ++++ + D K NEK + + + VT L Q E +N++ Sbjct: 630 NE--LIQNQKETNDNEKI--SELQKIVEDLKNENEKLKSEVNQKVTDL--QKAEGENDL- 682 Query: 973 NLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKI 1032 +++L + NLE I+ K+ ++ + E+ N++N L++ KD+ I +L ++ Sbjct: 683 -----IKKLQEENLE-IENEKDKEISELNEKLEKLQNQVNNLSSEKVTKDDIISSLQSEV 736 Query: 1033 NNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQI 1092 N+ Q S D + ++ K+E +E E ++S Q DS NEE+ L +++I Sbjct: 737 NDLQEEIESRKDDKQKEINSLKEKIETLENE--KISLQ--DSM--NEEIHKL----EEEI 786 Query: 1093 KELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQ 1152 L+ K E TE +S IE + + + +E EE + Sbjct: 787 SNLQNEKSVLE-----TENEKLSKQIEELQEKEKSSQ---------------EENEELSK 826 Query: 1153 ERSVLQEQSAKLNTELQECYTKI-IQLETLNTELTGHDVVNQEQINQLKSKLEQLNTEND 1211 + ++E+ +K + E +E K+ ++E + +L+ + + N + +++++ + D Sbjct: 827 QNEEMKEKLSKQDKEFEEEKEKLNAKIEKIEKDLSDGNNEKETLTNDFEDEVKRIEEDID 886 Query: 1212 NLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQL 1271 N + +L S ++ +L + L Q++ D +TE+ + + +E L Sbjct: 887 NKNKQIKQLEEEKSQLNEE--MNKLQLNNEFL-QKQKDVVETEN------NKIKKDFESL 937 Query: 1272 LDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEK 1331 L S+ + E K E+ L+ K E L N + + ++ I ++E++K Sbjct: 938 LSSLNKPDKSEMIKKFDEEKQQELEKTKTAKSE-LENQIHQMSIEKQKLTINLEKLENDK 996 Query: 1332 VAFXXXXXXXXXXXXXXXX---DLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXX 1388 + DL+ +N + + + I NE+N + +KS Sbjct: 997 LNLQNIVNDYQSKNSEMTKNLQDLQKKNFDLQNLYDDLINKTNEQNHRNEKSLENKDEEI 1056 Query: 1389 XXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTIT-LTQRNDEFENVRQQLV-EYEK 1446 ++ E+K+ L+ + +I K E I L + E N+ Q + E E Sbjct: 1057 KQLKDTQHELESKIESQLESLQNNEEKI--KLLESKIEDLEEEKLEQNNINQNKISELEH 1114 Query: 1447 RIEDLTYEK----ESELAILRLKMHENANHYETMQK-ESEIERVKLIEELNVKITESVSL 1501 +IE+L E+E I L+ ++ + ET++K +IE ++ +E +E+ S Sbjct: 1115 KIEELQNNSLNNDENENKISELE-NQVQEYQETIEKLRKQIEELEKEKENKADTSETESS 1173 Query: 1502 NKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMV---RASSSKIQKHV 1558 K + EL +EE + K N++ +N+ I+ L +E+T L N + R + K+++ Sbjct: 1174 TK-IKELEDKIEE-LEKENDL---FQNEGESILDLQEEVTKLNNEISTLRQLTCKLEEDN 1228 Query: 1559 SFASDTKQGRDEQLDNTMNKEL 1580 D + DE+L +++ K+L Sbjct: 1229 KTLKDGSE-EDEKLISSLRKQL 1249 Score = 66.1 bits (154), Expect = 8e-09 Identities = 86/430 (20%), Positives = 182/430 (42%), Gaps = 19/430 (4%) Query: 1169 QECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAV 1228 ++ Y + ++++ + EL + +I K LE ++ + DNL T E++ + Sbjct: 468 EKVYNALTEMKSNSYELWNEFEEDLIKIIMDKKPLENVS-QFDNL--TDEEVKKELKKLN 524 Query: 1229 D--QRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKI 1286 D + +I E +++ Q+ +D +K +L Q S Q LD++Q Q+ + Sbjct: 525 DDLKEKDKIIEENEKNNEQKVSDLKKQIEDLSKQKENENSDVLQKLDNLQKENQKLKEE- 583 Query: 1287 VTMEQVTSLQNKLQDKEEHLRNLQ-EKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXX 1345 E+ + LQ KL+ + E+L+N+ +K ++ L+ IED K Sbjct: 584 -NEEKESELQ-KLKQENENLKNIDAQKVTYDDEKVSELQKIIEDLKKENELIQNQKETND 641 Query: 1346 XXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRV---NDAEAKV 1402 +L+ + K E+ +N++ L+K+ + N+ + ++ Sbjct: 642 NEKISELQKIVEDLKNENEKLKSEVNQKVTDLQKAEGENDLIKKLQEENLEIENEKDKEI 701 Query: 1403 LELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAIL 1462 EL +LE +++ + E +T ++D +++ ++ + ++ IE +K+ E+ L Sbjct: 702 SELNEKLEKLQNQVNNLSSE-KVT---KDDIISSLQSEVNDLQEEIESRKDDKQKEINSL 757 Query: 1463 RLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEM 1522 + K+ N ++Q E KL EE++ E L + +L+K +EE K Sbjct: 758 KEKIETLENEKISLQDSMNEEIHKLEEEISNLQNEKSVLETENEKLSKQIEELQEKEKSS 817 Query: 1523 QTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHV-SFASDTKQGRDEQLDNTMNKELL 1581 Q E + + ++++ K+ + D G +E+ T+ + Sbjct: 818 QEENEELSKQNEEMKEKLSKQDKEFEEEKEKLNAKIEKIEKDLSDGNNEK--ETLTNDFE 875 Query: 1582 DAVPRAELDL 1591 D V R E D+ Sbjct: 876 DEVKRIEEDI 885 >UniRef50_A0BUU6 Cluster: Chromosome undetermined scaffold_13, whole genome shotgun sequence; n=1; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_13, whole genome shotgun sequence - Paramecium tetraurelia Length = 1010 Score = 144 bits (349), Expect = 2e-32 Identities = 207/1009 (20%), Positives = 438/1009 (43%), Gaps = 80/1009 (7%) Query: 510 EQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQ 569 ++I QL I N + +SN K ++ ++ +D V D+N+ ++ + L S Sbjct: 12 KKIAQLTKVIFFLNTKNDEYESNLKAVVQAYEQEMDQI--VKDANQIVLTYKQALDKQS- 68 Query: 570 KVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEM--ENLAETRLKAISLLESQKFDLV 627 K ++++E LQ + IE Y+K +E + L K I ++ + Sbjct: 69 KNDDIQQELKQLQEKVQVEKQTAQIEYSQYRKRMEEKEQGLVTQYEKKIKDIQKETEFQK 128 Query: 628 QELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKEL--ALVIENL 685 Q+ L ++ D+V K ++ + Q+ IK +E+ D L K E + ++ Sbjct: 129 QKFDDLSKQVDKVIMKQEELRRGSQKQLEDTIKE--WKEKYDTLMRKKLEQDDQIAEKDR 186 Query: 686 KLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQS 745 +L K+QL + +D++ K++ +++ + D+L+ + + + L + +E S Sbjct: 187 RLQKQQL---------EIDDLLKKIEEEKRKSKEAQDRLQDLMKQNFDQKLQSLQNEINS 237 Query: 746 KIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIA-----VMEDRRYSLERKAD 800 Q + + + + N+ E+++ K +I +L + + + L +K + Sbjct: 238 LKQEVTNLKNQKDDLTKHNHNLSDEVNQLKDQIAKLTLDLKDIGQKYQQSQTEVLSQKNE 297 Query: 801 -----QLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKN 855 Q S L++K K + Q + L ++L + E QL + + + E Q K+ Sbjct: 298 NSKLKQTNSDLEDKIKQLNS---QIENLKSQLHAYQQDGSMRETQLTK-QLSDLEQQLKS 353 Query: 856 QILLEENQNLQISLSDMQQHYNALVEKANRT-DLAESESTKYQTQLRDLESNLKRITHEH 914 + E + L I L+++Q+ + L + N D ++ ++ ++ +L+ N++R+ E Sbjct: 354 KDF--EIRELHIKLNELQKKADMLQMELNAVRDASDRSNSDKLKEIEELKKNVRRLEDEI 411 Query: 915 QTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYV-TQLEAQLQEYKNNIEN 973 + L Q K ++ +LE +IE +K+ L ++YE+ I+ + T+ E +L+E + +EN Sbjct: 412 EKLQNQAKNQMGELEKNLLNKIEQIEAEKRELIKRYEEKIQKITTEYELKLKELREELEN 471 Query: 974 LNMNVEELNKMNLELID-------KHVQKQQTQSPDYTEQYINE-INKLNALLKQKDEEI 1025 N+E + +E I K +++Q E+ + IN L + Q + +I Sbjct: 472 KIKNLENNHAQEIESIKNDFNKRLKQLEQQLNDERANVEKSAGQAINDLKNQINQANLKI 531 Query: 1026 IALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVS------KQLLDSKQHNE 1079 L +I N Q + L Q T+K + +++ +QR++ KQ+ N+ Sbjct: 532 SGLESEIQNLQNKIKELEQTIIYNLNQITSKEQEIKQLLQRIAELEDKIKQIQSEGSSNQ 591 Query: 1080 -ELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXX 1138 +LQ ++E + QIK+ + L + + + I+ + Sbjct: 592 GQLQTRIQELEQQIKQQRIDLLREKDEQLNQQKLSYEQQIDSLRQQYEAEKKQIKVDFER 651 Query: 1139 XXXLKVQEEEEFIQERSVLQE----------QSAKLNTELQECYTKIIQLETLNTELTGH 1188 LK +E + +Q+ + L++ + KL E E K I L+ N E+ Sbjct: 652 KLQLKEEEIAKLLQQITSLKKDMETGQGDWARRLKLKEEEFEQMLKEINLKH-NYEIELL 710 Query: 1189 DVVNQEQINQLKSKLE-QLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQRE 1247 D N + Q+K E ++ D+L E ++ ++ + + L K + Q + Sbjct: 711 DKKNTQMKEQMKVYYEKEIQQIKDDL---NVETQNKLNQQAREFENQKQSLIKNYENQLQ 767 Query: 1248 ADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLR 1307 Q+ E +L ++S FE+K +QL + ++ QE+++ T + ++ L+ +L++ E + Sbjct: 768 DVQQRYERQLNDKISEFENKLKQLQNKLE---QEQSDHKATKDIISDLRRQLENSLELNK 824 Query: 1308 NLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSI 1367 N +KY QI+IL+ +I+D + + ++ + KQ+++Q Sbjct: 825 NTSDKYE---QQIKILQQQIKDLNIKYQQAEVEFSKQIKEKDVWVQQMKEEAKQLEQQLR 881 Query: 1368 LNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITL 1427 ++N+ QLK S A+ +++ LE EI + E Sbjct: 882 QSLNQ---QLKDSLIKQKDFADNLKNEFEQAQQLLMQKLQMLEEDYKEITRLYEE----R 934 Query: 1428 TQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETM 1476 R ++ E ++Q + + E++ E ++ +L++ N+Y M Sbjct: 935 PSRPEDLELIKQLQSQVNLKDEEIKKVNE-QMKYFKLELINRDNNYNKM 982 Score = 93.1 bits (221), Expect = 6e-17 Identities = 183/918 (19%), Positives = 394/918 (42%), Gaps = 92/918 (10%) Query: 169 ETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAM 228 E I D+Q++ + Q + +K EDT ++ + + + Sbjct: 114 EKKIKDIQKETEFQKQKFDDLSKQVDKVIMKQEELRRGSQKQLEDTIKEWKEKYDTLMRK 173 Query: 229 EAEWKD---EKQRLLK--DIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXX 283 + E D EK R L+ +E D+ EE K EA L Q+L+ Sbjct: 174 KLEQDDQIAEKDRRLQKQQLEIDDLLKKIEEEKRKSKEAQDRLQDLMKQNFDQKLQSLQN 233 Query: 284 XXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSL--EIANMTELTKKI---------ELL- 331 L Q + + +E L +IA +T K I E+L Sbjct: 234 EINSLKQEVTNLKNQKDDLTKHNHNLSDEVNQLKDQIAKLTLDLKDIGQKYQQSQTEVLS 293 Query: 332 -EHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLS 390 ++ N +++QTN +LE+K+ + ++ + + S ++ G +++ S L Sbjct: 294 QKNENSKLKQTNSDLEDKIKQLNSQIENLKSQLH-----AYQQDGSMRETQLTKQLSDLE 348 Query: 391 SETLNQDTDKK---INKNEI-AKLEMVIQSLN--KDLVDKEYVISEKDTXXXXXXXXXXG 444 + ++D + + I NE+ K +M+ LN +D D+ K+ Sbjct: 349 QQLKSKDFEIRELHIKLNELQKKADMLQMELNAVRDASDRSNSDKLKEIEELKKNVRRLE 408 Query: 445 KDTLIAQLQLEHQQ-HMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIE 503 + Q Q ++Q +E L + + E+ K E+ Q++ E ++ +K+L E Sbjct: 409 DEIEKLQNQAKNQMGELEKNLLNKIEQIEAEKRELIKRYEEKIQKITTEY-ELKLKELRE 467 Query: 504 KLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEE 563 +L E +I L + A IK N +LK + Q + + + + I L + Sbjct: 468 EL---ENKIKNLENN-HAQEIESIKNDFNKRLKQLEQQLNDERANVEKSAGQAINDLKNQ 523 Query: 564 LHHLSQKVAELEEEKGNLQLHL------VDYDSGRMIESDVYKKMIEMENLAETRLKAIS 617 ++ + K++ LE E NLQ + + Y+ ++ + K + ++ +AE K I Sbjct: 524 INQANLKISGLESEIQNLQNKIKELEQTIIYNLNQITSKEQEIKQL-LQRIAELEDK-IK 581 Query: 618 LLESQKFDLVQELHI-LQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDAL----S 672 ++S+ +L +Q+ +++ + D+ + + +Q+ + + E+QID+L Sbjct: 582 QIQSEGSSNQGQLQTRIQELEQQIKQQRIDLLREKDEQLNQQ--KLSYEQQIDSLRQQYE 639 Query: 673 ASKKELALVIE-NLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEK 731 A KK++ + E L+L +E++ ++ + + K+D M Q D +L K+ E+ Sbjct: 640 AEKKQIKVDFERKLQLKEEEIAKLLQQITSLKKD-METGQG------DWARRL-KLKEEE 691 Query: 732 ISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDR 791 ++L +IN + +I+ +D K + E Y+ I ++++ + V Sbjct: 692 FEQMLKEINLKHNYEIEL---LDKKNTQMK------EQMKVYYEKEIQQIKDDLNVETQN 742 Query: 792 RYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKEL 851 + + Q + +KQ Y Q ++ R ++R + ++ E E++ K+L Sbjct: 743 KLN-----QQAREFENQKQSLIKNYENQLQDVQQR------YERQLNDKISEFENKLKQL 791 Query: 852 QKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRIT 911 Q K LE+ Q+ + D+ +E N +L ++ S KY+ Q++ L+ +K + Sbjct: 792 QNK----LEQEQSDHKATKDIISDLRRQLE--NSLELNKNTSDKYEQQIKILQQQIKDLN 845 Query: 912 HEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNI 971 ++Q V+ K+I++ ++ E A + ++ L + + ++ L Q +++ +N+ Sbjct: 846 IKYQQAEVEFSKQIKEKDVWVQQMKEEAKQLEQQLRQSLNQQLK--DSLIKQ-KDFADNL 902 Query: 972 ENLNMNVEELNKMNLELID---KHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIAL 1028 +N ++L L++++ K + + + P E + I +L + + KDEEI + Sbjct: 903 KNEFEQAQQLLMQKLQMLEEDYKEITRLYEERPSRPED-LELIKQLQSQVNLKDEEIKKV 961 Query: 1029 NQKINNAQVSYMSMVSDY 1046 N+++ ++ ++ ++Y Sbjct: 962 NEQMKYFKLELINRDNNY 979 Score = 58.0 bits (134), Expect = 2e-06 Identities = 88/460 (19%), Positives = 188/460 (40%), Gaps = 31/460 (6%) Query: 1142 LKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKS 1201 L + +E ++V+Q +++ +++ ++ + + + +D + QE LK Sbjct: 24 LNTKNDEYESNLKAVVQAYEQEMDQIVKDANQIVLTYKQALDKQSKNDDIQQE----LKQ 79 Query: 1202 KLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHE-LRVQ 1260 E++ E ++ R + ++G K Q+E +FQK + + L Q Sbjct: 80 LQEKVQVEKQTAQIEYSQYRKRMEEK--EQGLVTQYEKKIKDIQKETEFQKQKFDDLSKQ 137 Query: 1261 LSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQI 1320 + K E+L Q ++ + E+ +L K ++++ + + +I Sbjct: 138 VDKVIMKQEELRRGSQKQLEDTIKE--WKEKYDTLMRKKLEQDDQIAEKDRRLQKQQLEI 195 Query: 1321 EILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILN-INEENAQLKK 1379 + L +IE+EK DL +N K Q+ +N + +E LK Sbjct: 196 DDLLKKIEEEK--------RKSKEAQDRLQDLMKQNFDQKLQSLQNEINSLKQEVTNLKN 247 Query: 1380 SSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKD-SEIYQKTHEYTITLTQRNDEFENVR 1438 VN + ++ +LT L+LKD + YQ++ T L+Q+N+ ++ Sbjct: 248 QKDDLTKHNHNLSDEVNQLKDQIAKLT--LDLKDIGQKYQQSQ--TEVLSQKNEN-SKLK 302 Query: 1439 QQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKE-SEIER-VKL----IEELN 1492 Q + E +I+ L + E+ + L + + + K+ S++E+ +K I EL+ Sbjct: 303 QTNSDLEDKIKQLNSQIENLKSQLHAYQQDGSMRETQLTKQLSDLEQQLKSKDFEIRELH 362 Query: 1493 VKITE-SVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASS 1551 +K+ E + ELN + ++ +E + + L DEI LQN + Sbjct: 363 IKLNELQKKADMLQMELNAVRDASDRSNSDKLKEIEELKKNVRRLEDEIEKLQNQAKNQM 422 Query: 1552 SKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDL 1591 +++K++ + + +L +++ EL L Sbjct: 423 GELEKNLLNKIEQIEAEKRELIKRYEEKIQKITTEYELKL 462 >UniRef50_UPI0000499259 Cluster: hypothetical protein 388.t00006; n=1; Entamoeba histolytica HM-1:IMSS|Rep: hypothetical protein 388.t00006 - Entamoeba histolytica HM-1:IMSS Length = 1598 Score = 144 bits (348), Expect = 2e-32 Identities = 227/1080 (21%), Positives = 488/1080 (45%), Gaps = 108/1080 (10%) Query: 457 QQHMEGPSLIHVGTNTEDVNEIAKVQEQL-KQELNDEIKDVNVKDLIEKLKSAEEQITQL 515 QQ+ P + +G++ + + K Q L K DE+ + K+ +EKLK A+E++++L Sbjct: 300 QQNQTIPIIDSIGSSR--IKKTQKEQRGLNKINSFDEVVEKKRKEDLEKLKKAKEELSKL 357 Query: 516 NDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELE 575 +E AA K K ++N K++ + ++ + EI +L E S ++ + + Sbjct: 358 EEEKIAAEKE--KEEANEKVQKLE--------EEMREKKIEIEKLKVEREE-SFRLLKGQ 406 Query: 576 EEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQ 635 +E+ ++ V+ + + I+ +V K E E LK I LE+ +L E + Sbjct: 407 KEQSLCEIQRVEQEKEKRIKEEVEKAHQLREKEFEELLKRIKELEA--INLENEYN---- 460 Query: 636 KYDEVEDKLADISQLQSDQ-----VCSEIKSVHLE--EQIDALSASKKELALVIENLKLD 688 DE++ K +IS +Q ++ + EIK + + ++I+ L K+E A + E +K + Sbjct: 461 -KDELKKKCLEISNIQEEKEELILIVQEIKEENEKRIKEIENLQEKKEENARIFEEMKKE 519 Query: 689 KEQLYGTI-------KDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINH 741 E+ + +L+N+ + I NK N +++ LT+++E + E ++ Sbjct: 520 IEEREKELIIERKQEIELQNEVQRITNKSNNNVEK---LTNQIEVLQKEINNQRSLLQEI 576 Query: 742 EEQSKIQTQFGIDAKIQE---RDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERK 798 EE++K+ +AKI+E ++ + E + K + R+ + +M++ L ++ Sbjct: 577 EEKNKLFNNEIKEAKIKEEQTKEFFTEEMNQITKKGEEERNRIMKENVIMKEEIKKLNKE 636 Query: 799 ADQLGSYLQEKQ------KAYSEYTIQE-DELVNRLAVLMDHDRVVEKQLLEIEHENKEL 851 +++ +K+ K + IQ+ +E+ N L + ++K + E+E NK Sbjct: 637 KEEMNEKYNKKEIENEDDKEKLKNEIQKREEIENNKISLQNQIFQLKKIIEELEEGNKYN 696 Query: 852 QKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESES--TKYQTQLRDLESNLKR 909 K IL EE I + +++ + ++ + E E K + +++ E N K Sbjct: 697 TNKINILTEECSKKDIEIEKIKKEFEQEIKNEREEQIKEKEDEIIKIKEEMKMAEENYKN 756 Query: 910 ----ITHEHQTLIVQKKKEIEDLEIEFNTQI-ESAIRDKKVLNEKYEKNI--EYVTQLEA 962 I + I Q K+E ++ E E + + I K+++ +K E I E + + Sbjct: 757 NISTIRTKKDLEIHQLKEEEQNKEKEIDILTNQKEIISKELITKKEENEILKEKINETLK 816 Query: 963 QL---QEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKL-NALL 1018 +L +E N + +N ++E K I K +++ T E+ N NK+ N Sbjct: 817 ELKEKEESNNQYQQINEEMKEKLKEKENEI-KIKEEKITNKEKEMEELKNNFNKVENENE 875 Query: 1019 KQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHN 1078 K+ E+I LN++I + S + + + E A L+N EE++ + ++++ SK + Sbjct: 876 KRFKEKINELNKEIEEQKKS-IKNIKEEEYLFADII--LDN--EEIKELKEEMIHSKLNR 930 Query: 1079 EELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXX 1138 + ++++ +++ +Q+ K+ ++ I ++ I + I+ +D+ ++ Sbjct: 931 KMIELIKKKEMEQLINDKK-----DLEIQLSKHQIENQKIQNQNDELKKINQTKENEKVL 985 Query: 1139 XXXL--KVQEEEEFIQERSVLQE-QSAKLNTELQECYTKIIQLETLNTELTGHDVVN-QE 1194 + K+Q + ++E+ +QE ++ KL +E+ Y+K I T EL + + Sbjct: 986 LNEINEKLQNKINELKEKDKIQEDENNKLQSEITN-YSKTITSLTEKIELCKTENTKIEN 1044 Query: 1195 QINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTE 1254 +I Q ++++E++ E + L EL I + + FE ++ +Q + Q E Sbjct: 1045 KIQQKENEIEEIKKEKEIALE---ELNHEIKKKI--KDFE-NQIKEQEIIQNNQIITIKE 1098 Query: 1255 HELRV-QLSAFESKYEQLLDSVQ-SSTQEETNKIVTM-EQVTSLQNKLQDKEEHLRNLQE 1311 + + +L K +++++ +EE NKI+ + E+ L+NK ++ + + L++ Sbjct: 1099 KDQNIYELKQHIEKMKKIIEETPLKEYEEENNKILKLKEENELLENKNKENIQKIEVLKK 1158 Query: 1312 KYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNIN 1371 K ++ N++++ IE EK+ + + E + K +Q + + Sbjct: 1159 KEEELNNKMQL----IEQEKINLNKEINIEIQKLKEELENEKNEKEKMKDFIKQKEIELQ 1214 Query: 1372 EENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRN 1431 +E + + ++ D + K+ ++ + + QK E + Sbjct: 1215 KEKDEKE----------CIIQQKIRDEKEKINAQESVRKMAEKIVQQKIEENQKKNILES 1264 Query: 1432 DEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQK--ESEIERVKLIE 1489 E E ++ +E EK I EK+ E I+ ++ E ++K + +IE +KLIE Sbjct: 1265 LEEEKRNRKKIENEKEI----IEKDKE--IMEKNINSLKEEIEELKKKDKKKIEDIKLIE 1318 Score = 135 bits (327), Expect = 8e-30 Identities = 199/1015 (19%), Positives = 440/1015 (43%), Gaps = 93/1015 (9%) Query: 603 IEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSV 662 I + +T+ + L + FD V E ++ ++++ ++S+L+ +++ +E + Sbjct: 311 IGSSRIKKTQKEQRGLNKINSFDEVVEKK-RKEDLEKLKKAKEELSKLEEEKIAAEKEKE 369 Query: 663 HLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQEN----M 718 E++ L +E + IE LK+++E+ + +K KE + ++Q QE Sbjct: 370 EANEKVQKLEEEMREKKIEIEKLKVEREESFRLLK---GQKEQSLCEIQRVEQEKEKRIK 426 Query: 719 DLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRI 778 + +K ++ ++ ELL +I E ++ ++ D +++++ L I NI+ E + + Sbjct: 427 EEVEKAHQLREKEFEELLKRIKELEAINLENEYNKD-ELKKKCLEISNIQEEKEELILIV 485 Query: 779 CRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVE 838 ++E +L+ K ++ +E +K E +E EL+ ++ V+ Sbjct: 486 QEIKEENEKRIKEIENLQEKKEENARIFEEMKKEIEE---REKELIIERKQEIELQNEVQ 542 Query: 839 KQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQT 898 + + + ++L + ++L +E N + L ++++ + + E ++ ++ T Sbjct: 543 RITNKSNNNVEKLTNQIEVLQKEINNQRSLLQEIEEKNKLFNNEIKEAKIKEEQTKEFFT 602 Query: 899 Q-----LRDLESNLKRITHEHQTL---IVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKY 950 + + E RI E+ + I + KE E++ ++N + DK+ L + Sbjct: 603 EEMNQITKKGEEERNRIMKENVIMKEEIKKLNKEKEEMNEKYNKKEIENEDDKEKLKNEI 662 Query: 951 EKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMN---LELIDKHVQKQQTQSPDYTEQY 1007 +K E + + LQ ++ + +EE NK N + ++ + K+ + +++ Sbjct: 663 QKR-EEIENNKISLQNQIFQLKKIIEELEEGNKYNTNKINILTEECSKKDIEIEKIKKEF 721 Query: 1008 INEI-NKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQR 1066 EI N+ +K+K++EII + +++ A+ +Y + +S +K ++ ++EE Q Sbjct: 722 EQEIKNEREEQIKEKEDEIIKIKEEMKMAEENYKNNISTIRTKK---DLEIHQLKEEEQN 778 Query: 1067 VSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDAN 1126 K E+ IL +++ KEL K E+ K I+ T++ + + Sbjct: 779 KEK----------EIDILTNQKEIISKELITKKEENEILKEK-----INETLKELKEKEE 823 Query: 1127 NVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELT 1186 + + LK +E E I+E + ++ E++E ++E N + Sbjct: 824 SNNQYQQINEEMKEKLKEKENEIKIKEEKITNKEK-----EMEELKNNFNKVENENEKRF 878 Query: 1187 GHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQR 1246 +E+IN+L ++E+ N+ I +D EI EL K+ + Sbjct: 879 ------KEKINELNKEIEEQKKSIKNIKEEEYLFADII---LDNE--EIKEL-KEEMIHS 926 Query: 1247 EADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHL 1306 + + + E + ++ + + L + S Q E KI N+ ++ E+ L Sbjct: 927 KLNRKMIELIKKKEMEQLINDKKDL-EIQLSKHQIENQKIQNQNDELKKINQTKENEKVL 985 Query: 1307 RN-LQEKYADVINQIEILRSEIEDE--KVAFXXXXXXXXXXXXXXXXDL-RTENQSYKQM 1362 N + EK + IN+++ EDE K+ +L +TEN + Sbjct: 986 LNEINEKLQNKINELKEKDKIQEDENNKLQSEITNYSKTITSLTEKIELCKTENTKIENK 1045 Query: 1363 QEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHE 1422 +Q I E +KK ++ + K+ + +Q+ K+ EI Q Sbjct: 1046 IQQKENEIEE----IKKEKEIALEELN------HEIKKKIKDFENQI--KEQEIIQNNQ- 1092 Query: 1423 YTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEI 1482 IT+ +++ ++Q + + +K IE+ ++ E LK+ E E KE+ I Sbjct: 1093 -IITIKEKDQNIYELKQHIEKMKKIIEETPLKEYEEENNKILKLKEENELLENKNKEN-I 1150 Query: 1483 ERVKLI----EELNVKIT----ESVSLNKQV----AELNKALEEEVAKTNEMQTALENQE 1530 ++++++ EELN K+ E ++LNK++ +L + LE E + +M+ ++ +E Sbjct: 1151 QKIEVLKKKEEELNNKMQLIEQEKINLNKEINIEIQKLKEELENEKNEKEKMKDFIKQKE 1210 Query: 1531 IEIVTLNDE-ITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAV 1584 IE+ DE +Q +R KI S ++ ++++ K +L+++ Sbjct: 1211 IELQKEKDEKECIIQQKIRDEKEKINAQESVRKMAEKIVQQKIEENQKKNILESL 1265 Score = 134 bits (325), Expect = 1e-29 Identities = 214/999 (21%), Positives = 445/999 (44%), Gaps = 97/999 (9%) Query: 233 KDEKQRLLKDIESKDVRISSLEEANKL---LEAARFEISLEHSKLAQELEQXXXXXXXXX 289 K K+ L K E K EEAN+ LE E +E KL E E+ Sbjct: 348 KKAKEELSKLEEEKIAAEKEKEEANEKVQKLEEEMREKKIEIEKLKVEREESFRLLKGQK 407 Query: 290 XXXXXLAKQSIEPSCEE--KTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELEN 347 Q +E E+ K E+E+ L EL K+I+ LE +N + EL+ Sbjct: 408 EQSL-CEIQRVEQEKEKRIKEEVEKAHQLREKEFEELLKRIKELEAINLENEYNKDELKK 466 Query: 348 KLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEI 407 K + + K+ LI ++ ++K E N K+ N Sbjct: 467 KCLEISNIQE-----EKEELILIVQEIKEENEKRIK--------EIENLQEKKEENARIF 513 Query: 408 AKLEMVIQSLNKDL-VDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLI 466 +++ I+ K+L ++++ I ++ + L Q+++ ++ SL+ Sbjct: 514 EEMKKEIEEREKELIIERKQEIELQNEVQRITNKSNNNVEKLTNQIEVLQKEINNQRSLL 573 Query: 467 HVGTNTEDV--NEI--AKV-QEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDA 521 + NEI AK+ +EQ K+ +E+ + K E+ + +E + + +EI Sbjct: 574 QEIEEKNKLFNNEIKEAKIKEEQTKEFFTEEMNQITKKGEEERNRIMKENVI-MKEEIKK 632 Query: 522 ANKNMIKVKSNHKLKLKQM------QKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELE 575 NK K + N K K++ +K + K + + L ++ L + + ELE Sbjct: 633 LNKE--KEEMNEKYNKKEIENEDDKEKLKNEIQKREEIENNKISLQNQIFQLKKIIEELE 690 Query: 576 E-EKGNL-QLHLVDYD-SGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHI 632 E K N +++++ + S + IE + KK E E + R + I E + + +E+ + Sbjct: 691 EGNKYNTNKINILTEECSKKDIEIEKIKKEFEQE-IKNEREEQIKEKEDEIIKIKEEMKM 749 Query: 633 LQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASK----KELALVIENLKLD 688 ++ Y + L+ Q+ E + E++ID L+ K KEL E ++ Sbjct: 750 AEENYKNNISTIRTKKDLEIHQLKEE--EQNKEKEIDILTNQKEIISKELITKKEENEIL 807 Query: 689 KEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLE---KMSAEKIS-------EL--- 735 KE++ T+K+L+ +KE+ N+ Q +E + + E K+ EKI+ EL Sbjct: 808 KEKINETLKELK-EKEESNNQYQQINEEMKEKLKEKENEIKIKEEKITNKEKEMEELKNN 866 Query: 736 LAKINHEEQSKIQTQFG-IDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYS 794 K+ +E + + + + ++ +I+E+ I+NI+ E + I EE + E+ +S Sbjct: 867 FNKVENENEKRFKEKINELNKEIEEQKKSIKNIKEEEYLFADIILDNEEIKELKEEMIHS 926 Query: 795 -LERK---------ADQLGSYLQEKQKAYSEYTIQEDELVNRLAVL--MDHDRVVEKQLL 842 L RK +QL + ++ + S++ I+ ++ N+ L ++ + EK LL Sbjct: 927 KLNRKMIELIKKKEMEQLINDKKDLEIQLSKHQIENQKIQNQNDELKKINQTKENEKVLL 986 Query: 843 -----EIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQ 897 +++++ EL++K++I +EN LQ +++ + +L EK +L ++E+TK + Sbjct: 987 NEINEKLQNKINELKEKDKIQEDENNKLQSEITNYSKTITSLTEK---IELCKTENTKIE 1043 Query: 898 TQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYV 957 +++ E+ ++ I E + + + EI+ +F E+ I++++++ I + Sbjct: 1044 NKIQQKENEIEEIKKEKEIALEELNHEIKKKIKDF----ENQIKEQEIIQ---NNQIITI 1096 Query: 958 TQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNAL 1017 + + + E K +IE + +EE E + + K + ++ + I K+ + Sbjct: 1097 KEKDQNIYELKQHIEKMKKIIEETPLKEYEEENNKILKLKEENELLENKNKENIQKIE-V 1155 Query: 1018 LKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQL-LDSKQ 1076 LK+K+EE+ Q I +++ ++ KL + +N +E+M+ KQ ++ ++ Sbjct: 1156 LKKKEEELNNKMQLIEQEKINLNKEINIEIQKLKEELENEKNEKEKMKDFIKQKEIELQK 1215 Query: 1077 HNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXX 1136 +E + ++++ +I++ KE K+ + ++ K I+ IE + N+ Sbjct: 1216 EKDEKECIIQQ---KIRDEKE-KINAQESVRKMAEKIVQQKIE--ENQKKNI--LESLEE 1267 Query: 1137 XXXXXLKVQEEEEFIQ-ERSVLQEQSAKLNTELQECYTK 1174 K++ E+E I+ ++ ++++ L E++E K Sbjct: 1268 EKRNRKKIENEKEIIEKDKEIMEKNINSLKEEIEELKKK 1306 Score = 123 bits (297), Expect = 4e-26 Identities = 195/932 (20%), Positives = 393/932 (42%), Gaps = 75/932 (8%) Query: 692 LYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINH-----EEQSK 746 L+G++ + D E+ QN +D +K L KIN E++ K Sbjct: 282 LFGSVNESSVDSEEDRKDQQNQTIPIIDSIGSSRIKKTQKEQRGLNKINSFDEVVEKKRK 341 Query: 747 IQTQFGIDAKIQERDLYIENIESELSKYKS--RICRLEESIAVMEDRRYSLER-KADQLG 803 + AK + L E I +E K ++ ++ +LEE M +++ +E+ K ++ Sbjct: 342 EDLEKLKKAKEELSKLEEEKIAAEKEKEEANEKVQKLEEE---MREKKIEIEKLKVEREE 398 Query: 804 SY-LQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEEN 862 S+ L + QK S IQ E + + ++ + + E E K +++ I LE Sbjct: 399 SFRLLKGQKEQSLCEIQRVEQEKEKRIKEEVEKAHQLREKEFEELLKRIKELEAINLENE 458 Query: 863 QNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKK 922 N + N EK + + + + +++++E NL+ E+ + + K Sbjct: 459 YNKDELKKKCLEISNIQEEKEELILIVQEIKEENEKRIKEIE-NLQEKKEENARIFEEMK 517 Query: 923 KEIEDLE----IEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNV 978 KEIE+ E IE +IE +++ N K N+E +T LQ+ NN +L + Sbjct: 518 KEIEEREKELIIERKQEIELQNEVQRITN-KSNNNVEKLTNQIEVLQKEINNQRSLLQEI 576 Query: 979 EELNKM-NLELIDKHVQKQQTQSPDYTEQYINEINKL-----NALLKQK---DEEIIALN 1029 EE NK+ N E+ + ++++QT+ +TE+ +N+I K N ++K+ EEI LN Sbjct: 577 EEKNKLFNNEIKEAKIKEEQTKE-FFTEE-MNQITKKGEEERNRIMKENVIMKEEIKKLN 634 Query: 1030 QKINNAQVSYMSMV---SDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVR 1086 ++ Y D + KL K E +E + Q+ K+ EEL+ + Sbjct: 635 KEKEEMNEKYNKKEIENEDDKEKLKNEIQKREEIENNKISLQNQIFQLKKIIEELEEGNK 694 Query: 1087 EQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQE 1146 ++I L E ++ I K + + + N + +K++E Sbjct: 695 YNTNKINILTEECSKKDIEIEKIK--------KEFEQEIKN-EREEQIKEKEDEIIKIKE 745 Query: 1147 EEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQI--NQLKSKLE 1204 E + +E + + +L+ ++ E N E + NQ++I +L +K E Sbjct: 746 EMKMAEENYKNNISTIRTKKDLE---IHQLKEEEQNKEKEIDILTNQKEIISKELITKKE 802 Query: 1205 QLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAF 1264 + + + T+ EL+ S + + +I E K+ L ++E + + E ++ + Sbjct: 803 ENEILKEKINETLKELKEKEES--NNQYQQINEEMKEKLKEKENEIKIKEEKITNK---- 856 Query: 1265 ESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEK---YADVINQIE 1321 E + E+L ++ E + E++ L +++++++ ++N++E+ +AD+I E Sbjct: 857 EKEMEELKNNFNKVENENEKRF--KEKINELNKEIEEQKKSIKNIKEEEYLFADIILDNE 914 Query: 1322 ILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYK-QMQEQSILN--INEENAQLK 1378 ++ E+++E + L + + + Q+ + I N I +N +LK Sbjct: 915 EIK-ELKEEMIHSKLNRKMIELIKKKEMEQLINDKKDLEIQLSKHQIENQKIQNQNDELK 973 Query: 1379 KSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSE---IYQKTHEYTITLTQRNDEFE 1435 K + + K+ EL + ++++ E + + Y+ T+T ++ E Sbjct: 974 KINQTKENEKVLLNEINEKLQNKINELKEKDKIQEDENNKLQSEITNYSKTITSLTEKIE 1033 Query: 1436 -------NVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLI 1488 + ++ + E IE++ EKE L L ++ + +E KE EI + I Sbjct: 1034 LCKTENTKIENKIQQKENEIEEIKKEKEIALEELNHEIKKKIKDFENQIKEQEIIQNNQI 1093 Query: 1489 EELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVR 1548 + K L + + ++ K +EE K E EN +I + +E+ +N Sbjct: 1094 ITIKEKDQNIYELKQHIEKMKKIIEETPLKEYEE----ENNKILKLKEENELLENKNKEN 1149 Query: 1549 ASSSKIQKHVSFASDTKQGRDEQLDNTMNKEL 1580 ++ K + K EQ +NKE+ Sbjct: 1150 IQKIEVLKKKEEELNNKMQLIEQEKINLNKEI 1181 Score = 123 bits (296), Expect = 5e-26 Identities = 190/907 (20%), Positives = 404/907 (44%), Gaps = 92/907 (10%) Query: 222 QENFIAMEAEWKDEKQRLLKDIES----KDVRISSLEEANKLLEAARFEISLEHSK---L 274 +E I + E K+E ++ +K+IE+ K+ EE K +E E+ +E + L Sbjct: 478 KEELILIVQEIKEENEKRIKEIENLQEKKEENARIFEEMKKEIEEREKELIIERKQEIEL 537 Query: 275 AQELEQXXXXXXXXXXXXXX---LAKQSIEPSCEEKTEIEEKGSLEIANMTELT-KKIEL 330 E+++ + ++ I EIEEK L + E K+ + Sbjct: 538 QNEVQRITNKSNNNVEKLTNQIEVLQKEINNQRSLLQEIEEKNKLFNNEIKEAKIKEEQT 597 Query: 331 LEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLS 390 E ++ Q K+ E + + E+ + KK L K N K ++ Sbjct: 598 KEFFTEEMNQITKKGEEERNRIMKENVIMKEEIKK---LNKEKEEMNEKYNKKEIENEDD 654 Query: 391 SETLNQDTDKK--INKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTL 448 E L + K+ I N+I+ + Q L K + + E KD Sbjct: 655 KEKLKNEIQKREEIENNKISLQNQIFQ-LKKIIEELEEGNKYNTNKINILTEECSKKDIE 713 Query: 449 IAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEI------KDVNVKDLI 502 I +++ E +Q ++ + +++ +I + + ++ + I KD+ + L Sbjct: 714 IEKIKKEFEQEIKNEREEQIKEKEDEIIKIKEEMKMAEENYKNNISTIRTKKDLEIHQLK 773 Query: 503 EKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTE 562 E+ ++ E++I L ++ + +K +I K +++ +++ +T+ + +SN + ++ E Sbjct: 774 EEEQNKEKEIDILTNQKEIISKELITKKEENEILKEKINETLKELKEKEESNNQYQQINE 833 Query: 563 ELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQ 622 E + +K+ E E E ++ E + K EME L K + E + Sbjct: 834 E---MKEKLKEKENEI-------------KIKEEKITNKEKEMEELKNNFNKVENENEKR 877 Query: 623 KFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVI 682 + + EL+ ++ + + + L +D + + L+E++ ++K + L+ Sbjct: 878 FKEKINELNKEIEEQKKSIKNIKEEEYLFADIILDNEEIKELKEEMIHSKLNRKMIELI- 936 Query: 683 ENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISE--LLAKIN 740 K + EQL KDLE ++K Q Q+ + D+L+K++ K +E LL +IN Sbjct: 937 --KKKEMEQLINDKKDLEIQ----LSKHQIENQKIQNQNDELKKINQTKENEKVLLNEIN 990 Query: 741 HEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKAD 800 + Q+KI D KIQE + ++SE++ Y I L E I + + +E K Sbjct: 991 EKLQNKINELKEKD-KIQEDE--NNKLQSEITNYSKTITSLTEKIELCKTENTKIENKIQ 1047 Query: 801 QLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQ--KKNQIL 858 Q + ++E +K E ++E ++H+ ++K++ + E++ KE + + NQI+ Sbjct: 1048 QKENEIEEIKKE-KEIALEE----------LNHE--IKKKIKDFENQIKEQEIIQNNQII 1094 Query: 859 L--EENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQT 916 E++QN+ +++QH + + T L E E + + + ++ E++ Sbjct: 1095 TIKEKDQNIY----ELKQHIEKMKKIIEETPLKEYE---------EENNKILKLKEENEL 1141 Query: 917 LIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNM 976 L + K+ I+ +IE + E + +K L E+ + N+ ++ ++Q+ K +EN Sbjct: 1142 LENKNKENIQ--KIEVLKKKEEELNNKMQLIEQEKINLN--KEINIEIQKLKEELEN-EK 1196 Query: 977 NVEELNKMNLELIDKHVQKQQTQSPDYTEQYI-NEINKLNA--LLKQKDEEIIALNQKI- 1032 N +E K ++ + +QK++ + +Q I +E K+NA +++ E+I+ QKI Sbjct: 1197 NEKEKMKDFIKQKEIELQKEKDEKECIIQQKIRDEKEKINAQESVRKMAEKIV--QQKIE 1254 Query: 1033 NNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQI 1092 N + + + + + + + + E +E++ + + K + K+ EEL+ +++ + I Sbjct: 1255 ENQKKNILESLEEEKRNRKKIENEKEIIEKDKEIMEKNINSLKEEIEELKKKDKKKIEDI 1314 Query: 1093 KELKETK 1099 K ++ K Sbjct: 1315 KLIELIK 1321 Score = 84.6 bits (200), Expect = 2e-14 Identities = 160/790 (20%), Positives = 351/790 (44%), Gaps = 56/790 (7%) Query: 144 VTHLSNTIKEK-DNALSVLQVKMKIMETTILDLQEKIN-EKDQIIEAKNKATTXXXXXXX 201 +T+ SN EK N + VLQ ++ + + +++EK ++I EAK K Sbjct: 544 ITNKSNNNVEKLTNQIEVLQKEINNQRSLLQEIEEKNKLFNNEIKEAKIKEEQTKEFFTE 603 Query: 202 XXXXXXXXXXEDTKQQMTK---MQENFIAMEAEWKDEKQRL-LKDIESKDVRISSLEEAN 257 E+ + M + M+E + E ++ ++ K+IE++D + E Sbjct: 604 EMNQITKKGEEERNRIMKENVIMKEEIKKLNKEKEEMNEKYNKKEIENEDDKEKLKNEIQ 663 Query: 258 KLLEAARFEISLEHS--KLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCE-EKTEIEEKG 314 K E +ISL++ +L + +E+ L ++ + E EK + E + Sbjct: 664 KREEIENNKISLQNQIFQLKKIIEELEEGNKYNTNKINILTEECSKKDIEIEKIKKEFEQ 723 Query: 315 SLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKS 374 ++ ++ +K + + + +++ + +N ++T+ T+ K+ ++ Sbjct: 724 EIKNEREEQIKEKEDEIIKIKEEMKMAEENYKNNISTIRTKKDLEIHQLKEEEQNKEKEI 783 Query: 375 GRNTASKMKSPWSQLSSETLNQDTDKKINK--NEIAKLE---MVIQSLNKDLVDKEYVIS 429 T K ++ + N+ +KIN+ E+ + E Q +N+++ +K + Sbjct: 784 DILTNQKEIISKELITKKEENEILKEKINETLKELKEKEESNNQYQQINEEMKEK---LK 840 Query: 430 EKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAK-VQEQLKQE 488 EK+ K+ + +L+ + +E + E +NE+ K ++EQ K Sbjct: 841 EKENEIKIKEEKITNKEKEMEELK-NNFNKVENENEKRF---KEKINELNKEIEEQKKSI 896 Query: 489 LNDEIKDVNVKDLI---EKLKSAEEQI--TQLNDE-IDAANKNMIKVKSNHKLKLK-QMQ 541 N + ++ D+I E++K +E++ ++LN + I+ K ++ N K L+ Q+ Sbjct: 897 KNIKEEEYLFADIILDNEEIKELKEEMIHSKLNRKMIELIKKKEMEQLINDKKDLEIQLS 956 Query: 542 KTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKK 601 K K+ + N E+ ++ + + + E+ E+ N L + D ++ E + K Sbjct: 957 KHQIENQKIQNQNDELKKINQTKENEKVLLNEINEKLQNKINELKEKD--KIQEDENNKL 1014 Query: 602 MIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKS 661 E+ N ++T +E K + + + +QQK +E+E+ + ++ +++ EIK Sbjct: 1015 QSEITNYSKTITSLTEKIELCKTENTKIENKIQQKENEIEE-IKKEKEIALEELNHEIKK 1073 Query: 662 --VHLEEQIDALSASKKELALVIE-------NLKLDKEQLYGTIKDLE-NDKEDIMNKLQ 711 E QI + + I+ LK E++ I++ + E+ NK+ Sbjct: 1074 KIKDFENQIKEQEIIQNNQIITIKEKDQNIYELKQHIEKMKKIIEETPLKEYEEENNKIL 1133 Query: 712 NYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQ--TQFGIDAKIQERDLYIENIES 769 +EN +L + K + +KI E+L K E +K+Q Q I+ +E ++ I+ ++ Sbjct: 1134 KLKEEN-ELLENKNKENIQKI-EVLKKKEEELNNKMQLIEQEKINLN-KEINIEIQKLKE 1190 Query: 770 ELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAV 829 EL K+ ++++ I + + L+++ D+ +Q+K + E I E V ++A Sbjct: 1191 ELENEKNEKEKMKDFI---KQKEIELQKEKDEKECIIQQKIRDEKE-KINAQESVRKMAE 1246 Query: 830 LMDHDRVVEKQLLEIEHENKELQKKNQILLE-ENQNLQISLSDMQQHYNAL---VEKANR 885 + ++ E Q I E+ E +K+N+ +E E + ++ M+++ N+L +E+ + Sbjct: 1247 KIVQQKIEENQKKNI-LESLEEEKRNRKKIENEKEIIEKDKEIMEKNINSLKEEIEELKK 1305 Query: 886 TDLAESESTK 895 D + E K Sbjct: 1306 KDKKKIEDIK 1315 Score = 48.4 bits (110), Expect = 0.002 Identities = 66/344 (19%), Positives = 142/344 (41%), Gaps = 28/344 (8%) Query: 1262 SAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQ-- 1319 S F S E +DS + ++ I ++ + S + K KE+ N + +V+ + Sbjct: 281 SLFGSVNESSVDSEEDRKDQQNQTIPIIDSIGSSRIKKTQKEQRGLNKINSFDEVVEKKR 340 Query: 1320 ---IEILR------SEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNI 1370 +E L+ S++E+EK+A ++R + ++++ + + Sbjct: 341 KEDLEKLKKAKEELSKLEEEKIAAEKEKEEANEKVQKLEEEMREKKIEIEKLKVEREESF 400 Query: 1371 NEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQ------LELKDSEIYQKTHEYT 1424 Q ++S R+ + K +L + +K+ E +EY Sbjct: 401 RLLKGQKEQSLCEIQRVEQEKEKRIKEEVEKAHQLREKEFEELLKRIKELEAINLENEYN 460 Query: 1425 IT-LTQRNDEFENVRQQLVEYEKRIEDLTYEKES---ELAILRLKMHENANHYETMQKES 1480 L ++ E N++++ E ++++ E E E+ L+ K ENA +E M+KE Sbjct: 461 KDELKKKCLEISNIQEEKEELILIVQEIKEENEKRIKEIENLQEKKEENARIFEEMKKEI 520 Query: 1481 EIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEI 1540 E +LI E +I + + + N +E+ + +Q + NQ + + ++ Sbjct: 521 EEREKELIIERKQEIELQNEVQRITNKSNNNVEKLTNQIEVLQKEINNQRSLLQEIEEKN 580 Query: 1541 TNLQNMVRASSSKIQKHVSFASD-----TKQGRDEQLDNTMNKE 1579 N ++ + K ++ F ++ TK+G +E+ N + KE Sbjct: 581 KLFNNEIKEAKIKEEQTKEFFTEEMNQITKKGEEER--NRIMKE 622 >UniRef50_Q10411 Cluster: Sporulation-specific protein 15; n=1; Schizosaccharomyces pombe|Rep: Sporulation-specific protein 15 - Schizosaccharomyces pombe (Fission yeast) Length = 1957 Score = 144 bits (348), Expect = 2e-32 Identities = 281/1465 (19%), Positives = 608/1465 (41%), Gaps = 132/1465 (9%) Query: 172 ILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAE 231 I DL +I+E D + +++ + +D++ ++++E + E Sbjct: 321 IEDLSTRISEFDNL-KSERDTLSIKNEKLEKLLRNTIGSLKDSRTSNSQLEEEMV----E 375 Query: 232 WKDEKQRLLKDIESKDVRISSLEEANKLLEAARFE----ISLEHSKLAQELEQXXXXXXX 287 K+ + + + + ++SS E+ NK L+ + E +S + + Q Q Sbjct: 376 LKESNRTIHSQLTDAESKLSSFEQENKSLKGSIDEYQNNLSSKDKMVKQVSSQLEEARSS 435 Query: 288 XXXXXXXLAKQSIEPSCEEKT-----EIEE-------KGSLEIANMTELT-KKIELLEHL 334 LA+ + E + K +IE+ S E+ + L KK + L +L Sbjct: 436 LAHATGKLAEINSERDFQNKKIKDFEKIEQDLRACLNSSSNELKEKSALIDKKDQELNNL 495 Query: 335 NCQIRQTNKELENKLATMGTESKAVSSPSKKG----SPLISRKSGRNTA-SKMKSPWSQL 389 QI++ K E+ +++ + + + + KK S L K T S + SQL Sbjct: 496 REQIKEQKKVSESTQSSLQSLQRDILNEKKKHEVYESQLNELKGELQTEISNSEHLSSQL 555 Query: 390 SSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDK--EYVISEKDTXXXXXXXXXXGKDT 447 S+ ++ N NE+++ + +Q+L +K + V+ K+ K Sbjct: 556 STLAAEKEAAVATN-NELSESKNSLQTLCNAFQEKLAKSVMQLKENEQNFSSLDTSFKKL 614 Query: 448 LIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKS 507 + +LE+ L + + + EQ + L+DE D+ K L KL+ Sbjct: 615 NESHQELENNHQTITKQLKDTSSKLQQLQLERANFEQKESTLSDENNDLRTKLL--KLEE 672 Query: 508 AEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHL 567 + + + + +++D+ KN+ +K + L++ ++ + FSK+ N L E + +L Sbjct: 673 SNKSLIKKQEDVDSLEKNIQTLKED----LRKSEEAL-RFSKLEAKN-----LREVIDNL 722 Query: 568 SQKVAELEEEKGNLQLHLVDY-DSGRMIESDVYKKMIEMENLA---ETRLKAISLLESQK 623 K LE ++ +L L D ++ ++ S++ K +++ L ET + ++ Sbjct: 723 KGKHETLEAQRNDLHSSLSDAKNTNAILSSELTKSSEDVKRLTANVETLTQDSKAMKQSF 782 Query: 624 FDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIE 683 LV + Y E+ D ++ + + SE K L+ + L+ L ++ Sbjct: 783 TSLVNSYQSISNLYHELRDDHVNMQSQNNTLLESESK---LKTDCENLTQQNMTLIDNVQ 839 Query: 684 NLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEE 743 L + +L+ + L+N ++ ++++ +++EL + E Sbjct: 840 KLMHKHVNQESKVSELKEVNGKLSLDLKN-LRSSLNVAISDNDQILTQLAELSKNYDSLE 898 Query: 744 QSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLG 803 Q Q G+ + E+ L + +E + R+ +L + + E + L +K Sbjct: 899 QESAQLNSGLKSLEAEKQL----LHTENEELHIRLDKLTGKLKIEESKSSDLGKKL---- 950 Query: 804 SYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQL-LEIEH-ENK--ELQKKNQILL 859 + QE+ E + + + + + +D +L +IEH +NK E++ + LL Sbjct: 951 TARQEEISNLKEENMSQSQAITSVKSKLDETLSKSSKLEADIEHLKNKVSEVEVERNALL 1010 Query: 860 EENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIV 919 N+ L L + ++ +L ++E K + + DL+S L ++ E++ L++ Sbjct: 1011 ASNERLMDDLKNNGENIASL----------QTEIEKKRAENDDLQSKLSVVSSEYENLLL 1060 Query: 920 QKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEY--VTQLEAQLQEYKNNIENLNMN 977 + + LE + N +K+L+EK ++N+E +T +L E I++ + Sbjct: 1061 ISSQTNKSLEDKTNQLKYIEKNVQKLLDEKDQRNVELEELTSKYGKLGEENAQIKDELLA 1120 Query: 978 VEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQV 1037 + + +K +L V + +S D EQ NE N+L L+Q + N+ + + Sbjct: 1121 LRKKSKKQHDLCANFVDDLKEKS-DALEQLTNEKNELIVSLEQSNSN----NEALVEERS 1175 Query: 1038 SYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQI----LVREQDDQIK 1093 + +SD + L+ + + ++ RV+ +L K+ + L + +++DD + Sbjct: 1176 DLANRLSDMKKSLSDSDNVISVIRSDLVRVNDELDTLKKDKDSLSTQYSEVCQDRDDLLD 1235 Query: 1094 ELKETKLTFEMNIPKTEGMIISSTIE-PMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQ 1152 LK + +F + S I+ P+S+ ++ L V E ++ Sbjct: 1236 SLKGCEESFNKYAVSLRELCTKSEIDVPVSEILDDNFVFNAGNFSELSRLTVLSLENYLD 1295 Query: 1153 ERSVLQEQSAKLNTELQEC---YTKII-QLETLNTELTGHDVVNQEQINQLKSKLEQLNT 1208 + + + +L+ L +TK++ LE L E HD + + Q + L Sbjct: 1296 AFNQVNFKKMELDNRLTTTDAEFTKVVADLEKLQHE---HD----DWLIQRGDLEKALKD 1348 Query: 1209 ENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKY 1268 N L AE+ +I S + G E + L+ R D Q ++L+ QL + Sbjct: 1349 SEKNFLRKEAEMTENIHSL--EEGKEETKKEIAELSSRLEDNQLATNKLKNQLDHLNQEI 1406 Query: 1269 EQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIE 1328 +L + V +E+ + I+++E+ SL N+ Q KE L + + + +++ S + Sbjct: 1407 -RLKEDV---LKEKESLIISLEE--SLSNQRQ-KESSLLDAKNELEHMLDDTSRKNSSLM 1459 Query: 1329 DEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXX 1388 ++ + L + +++ +S+ + +QL+++ Sbjct: 1460 EKIESINSSLDDKSFELASAVEKLG----ALQKLHSESLSLMENIKSQLQEAKE------ 1509 Query: 1389 XXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRI 1448 ++ E+ + EL H++ + K ++ + ++ E + L E + + Sbjct: 1510 -----KIQVDESTIQELDHEITASKNNYEGKLNDKDSIIRDLSENIEQLNNLLAEEKSAV 1564 Query: 1449 EDLTYEKESELAILRLKMHENANHYETMQKESEIERVKL-----IEELNVKITESVSLNK 1503 + L+ EKESE IL+ Y Q ESE+ R KL EEL + E +SL Sbjct: 1565 KRLSTEKESE--ILQFNSRLADLEYHKSQVESELGRSKLKLASTTEELQLAENERLSLTT 1622 Query: 1504 QVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASD 1563 ++ + L+ +V + ++ +L + +L D + +LQ + S+ ++ + Sbjct: 1623 RMLD----LQNQVKDLSNIKDSLSEDLRTLRSLEDSVASLQKECKIKSNTVES-LQDVLT 1677 Query: 1564 TKQGRDEQLDNTMNKELLDAVPRAE 1588 + Q R+ +L++ +++ +D + R + Sbjct: 1678 SVQARNAELEDEVSRS-VDKIRRRD 1701 Score = 134 bits (325), Expect = 1e-29 Identities = 257/1356 (18%), Positives = 560/1356 (41%), Gaps = 117/1356 (8%) Query: 310 IEEKGSLEIANMTELTKKIELLEH----LNCQIRQTNKELENKLA-TMGTESKAVSSPSK 364 + +K +L + + ++ K+ LEH L+ Q+ +NK+ +N + T T + VS K Sbjct: 129 VTQKSNL-LNELKQVRSKLAALEHENGILSLQLSSSNKKDKNTSSVTTLTSEEDVSYFQK 187 Query: 365 KGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDK 424 K + + S S + + + S QL T+ + DKK + + K++ + S+ L ++ Sbjct: 188 KLTNMESNFSAKQSEAYDLS--RQLL--TVTEKLDKK--EKDYEKIKEDVSSIKASLAEE 241 Query: 425 EYVI-SEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQE 483 + S + T+ Q E+ E +L E +K+ E Sbjct: 242 QASNKSLRGEQERLEKLLVSSNKTVSTLRQTENSLRAECKTLQEKLEKCAINEEDSKLLE 301 Query: 484 QLKQELNDEIKDVNVKD-LIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQK 542 +LK + + + KD LIE L + + L E D + +K N KL+ K ++ Sbjct: 302 ELKHNVANYSDAIVHKDKLIEDLSTRISEFDNLKSERDT-----LSIK-NEKLE-KLLRN 354 Query: 543 TIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDS-GRMIESDVYKK 601 TI + SN + L EE+ L + + + + + L ++ + ++ + + Sbjct: 355 TIGSLKDSRTSNSQ---LEEEMVELKESNRTIHSQLTDAESKLSSFEQENKSLKGSIDEY 411 Query: 602 MIEMENLAETRLKAISLLESQKFDLVQ---ELHILQQKYDEVEDKLADISQLQSD-QVCS 657 + + + + S LE + L +L + + D K+ D +++ D + C Sbjct: 412 QNNLSSKDKMVKQVSSQLEEARSSLAHATGKLAEINSERDFQNKKIKDFEKIEQDLRACL 471 Query: 658 EIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMN---KLQNYI 714 S L+E+ + +EL + E +K K+ T L++ + DI+N K + Y Sbjct: 472 NSSSNELKEKSALIDKKDQELNNLREQIKEQKKVSESTQSSLQSLQRDILNEKKKHEVYE 531 Query: 715 QENMDLTDKL--EKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELS 772 + +L +L E ++E +S L+ + E+++ + T + + +L+ Sbjct: 532 SQLNELKGELQTEISNSEHLSSQLSTLAAEKEAAVATNNELSESKNSLQTLCNAFQEKLA 591 Query: 773 KY-------KSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVN 825 K + L+ S + + LE + L++ + ++ Sbjct: 592 KSVMQLKENEQNFSSLDTSFKKLNESHQELENNHQTITKQLKDTSSKLQQLQLERANFEQ 651 Query: 826 RLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNAL----VE 881 + + L D + + +LL++E NK L KK + + +N+Q D+++ AL +E Sbjct: 652 KESTLSDENNDLRTKLLKLEESNKSLIKKQEDVDSLEKNIQTLKEDLRKSEEALRFSKLE 711 Query: 882 KANRTDLAESESTKYQT---QLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIES 938 N ++ ++ K++T Q DL S+L + + L + K ED++ +E+ Sbjct: 712 AKNLREVIDNLKGKHETLEAQRNDLHSSLSDAKNTNAILSSELTKSSEDVK-RLTANVET 770 Query: 939 AIRDKKVLNEKYE---KNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQK 995 +D K + + + + + ++ L +L++ N+++ N + E ++ L+ +++ + Sbjct: 771 LTQDSKAMKQSFTSLVNSYQSISNLYHELRDDHVNMQSQNNTLLE-SESKLKTDCENLTQ 829 Query: 996 QQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYE---SKLAQ 1052 Q D ++ +++ + + + E L+ + N + S +SD + ++LA+ Sbjct: 830 QNMTLIDNVQKLMHKHVNQESKVSELKEVNGKLSLDLKNLRSSLNVAISDNDQILTQLAE 889 Query: 1053 FTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGM 1112 + +++E+E +++ L K E Q+L E ++ ++ KLT ++ I +++ Sbjct: 890 LSKNYDSLEQESAQLNSGL---KSLEAEKQLLHTENEE--LHIRLDKLTGKLKIEESKSS 944 Query: 1113 IISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECY 1172 + + ++ +N+ +K + +E + + S L+ L ++ E Sbjct: 945 DLGKKLTARQEEISNLKEENMSQSQAITSVK-SKLDETLSKSSKLEADIEHLKNKVSEVE 1003 Query: 1173 TKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISS--AVDQ 1230 + L N L N E I L++++E+ END+L S ++ + S + + Sbjct: 1004 VERNALLASNERLMDDLKNNGENIASLQTEIEKKRAENDDLQSKLSVVSSEYENLLLISS 1063 Query: 1231 RGFEIAELWKQHLAQREADFQK---TEHELRVQLSAFESKY-------EQLLDSV----- 1275 + + E L E + QK + + V+L SKY Q+ D + Sbjct: 1064 QTNKSLEDKTNQLKYIEKNVQKLLDEKDQRNVELEELTSKYGKLGEENAQIKDELLALRK 1123 Query: 1276 QSSTQEE---------TNKIVTMEQVTSLQNK----LQDKEEHLRNLQEKYADVINQIEI 1322 +S Q + K +EQ+T+ +N+ L+ + L E+ +D+ N++ Sbjct: 1124 KSKKQHDLCANFVDDLKEKSDALEQLTNEKNELIVSLEQSNSNNEALVEERSDLANRLSD 1183 Query: 1323 LRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLK--KS 1380 ++ + D L+ + S + + ++ LK + Sbjct: 1184 MKKSLSDSDNVISVIRSDLVRVNDELDT-LKKDKDSLSTQYSEVCQDRDDLLDSLKGCEE 1242 Query: 1381 SXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTI-TLTQRNDEFENVRQ 1439 S ++ + V E+ + ++ + + T+ +L D F V Sbjct: 1243 SFNKYAVSLRELCTKSEIDVPVSEILDDNFVFNAGNFSELSRLTVLSLENYLDAFNQVNF 1302 Query: 1440 QLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELN-----VK 1494 + +E + R+ E +A L HE H + + + ++E+ E N + Sbjct: 1303 KKMELDNRLTTTDAEFTKVVADLEKLQHE---HDDWLIQRGDLEKALKDSEKNFLRKEAE 1359 Query: 1495 ITESV--------SLNKQVAELNKALEEEVAKTNEMQTALE--NQEIEIV--TLNDEITN 1542 +TE++ K++AEL+ LE+ TN+++ L+ NQEI + L ++ + Sbjct: 1360 MTENIHSLEEGKEETKKEIAELSSRLEDNQLATNKLKNQLDHLNQEIRLKEDVLKEKESL 1419 Query: 1543 LQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNK 1578 + ++ + S++ QK S D K + LD+T K Sbjct: 1420 IISLEESLSNQRQKESSLL-DAKNELEHMLDDTSRK 1454 Score = 87.8 bits (208), Expect = 2e-15 Identities = 198/1001 (19%), Positives = 418/1001 (41%), Gaps = 109/1001 (10%) Query: 177 EKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEK 236 + + + Q++ +N+ D +++T QE ++ E + Sbjct: 909 KSLEAEKQLLHTENEELHIRLDKLTGKLKIEESKSSDLGKKLTARQEEISNLKEENMSQS 968 Query: 237 QRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSK-LAQELEQXXXXXXXXXXXXXXL 295 Q + ++SK L+E L ++++ E +EH K E+E Sbjct: 969 QAITS-VKSK------LDET--LSKSSKLEADIEHLKNKVSEVEVERNALLASNERLMDD 1019 Query: 296 AKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTE 355 K + E +TEIE+K + ++L+ E+L QTNK LE+K + Sbjct: 1020 LKNNGENIASLQTEIEKKRAENDDLQSKLSVVSSEYENLLLISSQTNKSLEDKTNQLKYI 1079 Query: 356 SKAVSSPSKKGSPLISRKSGRNT-ASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVI 414 K V L+ K RN ++ S + +L E + + + K + Sbjct: 1080 EKNVQK-------LLDEKDQRNVELEELTSKYGKLGEENAQIKDELLALRKKSKKQHDLC 1132 Query: 415 QSLNKDLVDK----EYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGT 470 + DL +K E + +EK+ + L+ + + + + Sbjct: 1133 ANFVDDLKEKSDALEQLTNEKNELIVSLEQSNSNNEALVEERSDLANRLSDMKKSLSDSD 1192 Query: 471 NTEDV--NEIAKVQEQL------KQELNDEIKDV--NVKDLIEKLKSAEEQITQLNDEID 520 N V +++ +V ++L K L+ + +V + DL++ LK EE + Sbjct: 1193 NVISVIRSDLVRVNDELDTLKKDKDSLSTQYSEVCQDRDDLLDSLKGCEESFNKY----- 1247 Query: 521 AANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTE-ELHHLSQKVAELEEEKG 579 A + + KS + + ++ DNF + + E+ RLT L + ++ +K Sbjct: 1248 AVSLRELCTKSEIDVPVSEILD--DNFVFNAGNFSELSRLTVLSLENYLDAFNQVNFKKM 1305 Query: 580 NLQLHLVDYDSG-RMIESDVYKKMIEMEN-LAETRLKAISLLESQK------FDLVQELH 631 L L D+ + +D+ K E ++ L + +L +S+K ++ + +H Sbjct: 1306 ELDNRLTTTDAEFTKVVADLEKLQHEHDDWLIQRGDLEKALKDSEKNFLRKEAEMTENIH 1365 Query: 632 ILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQ 691 L++ +E + ++A++S D +++ + L+ Q+D L+ +E+ L + LK +KE Sbjct: 1366 SLEEGKEETKKEIAELSSRLED---NQLATNKLKNQLDHLN---QEIRLKEDVLK-EKES 1418 Query: 692 LYGTIKD-LEN--DKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHE--EQSK 746 L ++++ L N KE + +N ++ +D T + EKI + + ++ + E + Sbjct: 1419 LIISLEESLSNQRQKESSLLDAKNELEHMLDDTSRKNSSLMEKIESINSSLDDKSFELAS 1478 Query: 747 IQTQFGIDAKIQERDL-YIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSY 805 + G K+ L +ENI+S+L + K +I +++ES +++ + + + Sbjct: 1479 AVEKLGALQKLHSESLSLMENIKSQLQEAKEKI-QVDES--TIQELDHEITASKNNYEGK 1535 Query: 806 LQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNL 865 L +K + + ++L N LA + V++ L E E++ LQ +++ E Sbjct: 1536 LNDKDSIIRDLSENIEQLNNLLA---EEKSAVKR--LSTEKESEILQFNSRLADLEYHKS 1590 Query: 866 QISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLI--VQKKK 923 Q+ S++ + L LAE+E T++ DL++ +K +++ +L ++ + Sbjct: 1591 QVE-SELGRSKLKLASTTEELQLAENERLSLTTRMLDLQNQVKDLSNIKDSLSEDLRTLR 1649 Query: 924 EIED----LEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVE 979 +ED L+ E + + + VL +N E ++ + + + + Sbjct: 1650 SLEDSVASLQKECKIKSNTVESLQDVLTSVQARNAELEDEVSRSVDKIRRRDDRCEHLSG 1709 Query: 980 ELNKMNLELIDKH-----VQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINN 1034 +L K++ +L ++H ++Q+ + ++ + + KL L + E++I + Sbjct: 1710 KLKKLHSQLEEQHETFFRAEQQRMTQLGFLKETVKKQEKLLKKLNLRQEQLIP-----RS 1764 Query: 1035 AQVSYMSMVSDYESKLAQFTTKLENMEEEMQ-------------RVSKQLLDS-KQHNEE 1080 + + Y S + D E ++ +L +E Q RV ++LDS KQ + Sbjct: 1765 SILVYESYIRDIEKEIIVLQERLNGIELSQQLPKGYFGYFFKTNRVEMEVLDSFKQQVAK 1824 Query: 1081 LQIL------VREQDDQIK---ELKETKLTFEMNIPKTEGM 1112 LQ L V+ ++D K E KE + TF+ K E + Sbjct: 1825 LQFLAGAEFIVKFKEDLEKCAAEEKEKQATFDNYSEKVENL 1865 Score = 37.1 bits (82), Expect = 4.0 Identities = 36/172 (20%), Positives = 75/172 (43%), Gaps = 14/172 (8%) Query: 1428 TQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKL 1487 T R E ++R + ++++E +E + LK H AN+ + + + + KL Sbjct: 268 TLRQTE-NSLRAECKTLQEKLEKCAINEEDSKLLEELK-HNVANYSDAI-----VHKDKL 320 Query: 1488 IEELNVKITESVSLNKQ-------VAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEI 1540 IE+L+ +I+E +L + +L K L + + +T+ E E+V L + Sbjct: 321 IEDLSTRISEFDNLKSERDTLSIKNEKLEKLLRNTIGSLKDSRTSNSQLEEEMVELKESN 380 Query: 1541 TNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDLA 1592 + + + + SK+ K DE +N +K+ + ++L+ A Sbjct: 381 RTIHSQLTDAESKLSSFEQENKSLKGSIDEYQNNLSSKDKMVKQVSSQLEEA 432 >UniRef50_A0CQM3 Cluster: Chromosome undetermined scaffold_24, whole genome shotgun sequence; n=2; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_24, whole genome shotgun sequence - Paramecium tetraurelia Length = 1305 Score = 143 bits (347), Expect = 3e-32 Identities = 220/1150 (19%), Positives = 492/1150 (42%), Gaps = 86/1150 (7%) Query: 475 VNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHK 534 V++I +++ +L Q D + N K L+E E+ L +I+ K ++++KS Sbjct: 155 VDQIQELERKLLQVQQDSRDNDNSKVLLE------EKCKHLEFQIENREKEILRLKSKLD 208 Query: 535 LKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMI 594 ++ ++K +S++ ++ R +L L+++ +L +E NL+ L + Sbjct: 209 IQGTNIEKLAQEHI-LSEAQQKAQRTQTQLDLLTEENTKLNDELSNLRKELQRFRKKPSQ 267 Query: 595 ESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELH-ILQQKYDEVEDKLADISQLQSD 653 + + +N + +S++E +K ++ IL Q E + + QLQ Sbjct: 268 PQNSSPNKSDKKNELNQIKQRLSVIEDEKEKNQEQFKKILSQLEYENSQLIEKVQQLQQQ 327 Query: 654 QVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDI---MNKL 710 ++K+++ E+ + A K + + NLK DKE T+K LE D + + +N++ Sbjct: 328 NEQLQLKALNAEQVVSAYQTDKMVFSKAVNNLKSDKENTVQTLKSLEEDNQKLRFQLNEM 387 Query: 711 QNYIQENMDLTDKLEKMSAEKISELLAKIN--HEEQSKIQTQFGIDAKIQERDLYIENIE 768 + +Q +L++ E K+N +E + + Q D + ER+L + + Sbjct: 388 DDQLQIQKSEYQQLQR-EKELYDRNYKKLNDEYEREKEFVQQLRQDKRDLEREL--DQEK 444 Query: 769 SELSKYKSRICRLEESIAVMED--RRYSLERKADQLGSY---LQEKQKAYSEYTIQEDEL 823 + + K R++ S ++ +++ E+K Q Q +Q + + D L Sbjct: 445 QVIRELKVEFERMDVSKQNLDSLLQKFKQEQKNQQQSQQHNPNQGQQLMMDQLRKENDLL 504 Query: 824 VNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQI-------LLEENQNLQISLSDMQQHY 876 + + ++++L E + +N EL+++ ++ L ++N NL + Q Sbjct: 505 TKEVQTTEGLIKSIKRELGEKDRDNYELKQQKRLLNDQLSELAQKNANLDSQIKLKLQDI 564 Query: 877 NALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQK----KKEIEDLEIEF 932 L ++ + +S+ Q + + + ++ T L+ Q+ K +I DL I F Sbjct: 565 AQLEQEVEQYKREQSKMRLNQQSILEQKQKIENETVGELKLLQQQNNSLKLQISDLGI-F 623 Query: 933 NTQIESAIR-DKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVE-ELNKMNLELID 990 N+Q+E ++ +++LNE+ +N + L Q E +N+ N + E++ NL Sbjct: 624 NSQLEEKLKIAQELLNEQRLENDKLQMNLRQQSDETFKYQQNVLRNKDKEMDYYNLTHEI 683 Query: 991 KHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSM-------- 1042 + ++ Q+ + E++ +E KL +++ Q+ +++ LN+ A + Sbjct: 684 ERLRDQERKILIEKERFQSENLKLESVINQQTKQMEFLNKLKEEAMKEARELRQMINGLK 743 Query: 1043 VSDYESK--LAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKL 1100 +D+E K + + K+ N E +Q +++QL + +L + E QI LK K Sbjct: 744 TNDHEIKNTSIKLSEKVNNYEMSLQDINEQLQKEISRSNKLYNELTESQSQISSLKLQKT 803 Query: 1101 TFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQ 1160 +E I + + ++ ++E ++ K+++E + +Q R + + Sbjct: 804 DYENQIRQLK--LLCESLEKQKEE-------LLQRLQQKNSTKIEDERQVLQLRELNENL 854 Query: 1161 SAKLNTELQECYTKIIQLETLNTELTGHDVVNQ-EQINQLKSKLEQLNTENDNLLSTVAE 1219 K+N ++ LE L +L +V NQ +++ + L+Q + +N + Sbjct: 855 EDKVNQYSEQNIQLKRSLEQL--DLERDEVQNQLDEVRETNISLQQQIKQMNNEIQKQQS 912 Query: 1220 LRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHE---LRVQLSAFESKYEQLLDSVQ 1276 S +S+ +RG+E A+ ++ L + QK ++E ++ L E ++ ++ +Q Sbjct: 913 KLSEVSTK-GERGYEAAQQLEEKLRDQIYKNQKLQNENDNVKYTLQIKEKEFHEMKSDIQ 971 Query: 1277 SSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXX 1336 +++ N+ + + + S+Q K + +++ ++ LQ++ + QI++ E+ D ++ + Sbjct: 972 ILSKD--NQSLNNQLIKSVQEK-ELQQQQIQFLQQQEIRLKEQIKMFDMEMHDLQLNYSE 1028 Query: 1337 XXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVN 1396 T + +Q + +L + +L+K R + Sbjct: 1029 VCAENQRL---------TVSIQQISLQHEEVL---QRGVELEKQEDFFKVQMQNASKRED 1076 Query: 1397 DAEAKVLELTHQLE---LKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTY 1453 + ++ + ++E K E ++ E Q EF + R+ ++ ED + Sbjct: 1077 QYQIQLQQYEREIERLNRKSEEYERQIRELLKDRDQLGKEFHSQRKISTGFQAAQED--F 1134 Query: 1454 EKESELAILRLKMHENANHYETMQKESEIERVKLI-EELNVKITESVSLNKQVAELNKAL 1512 ++ + ENAN +QK+ +++ +L E+ V E V + ++ ++N Sbjct: 1135 NRQIAQLEREKQYIENAN--RDLQKQVDLKDAQLSWEQKRVNEMEQVIIQERQMQMNTLQ 1192 Query: 1513 EEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRD-EQ 1571 E + K Q E ++ + N Q+M ++S S +D Q Sbjct: 1193 EIQQLKDQNEQLLQELEKAYQPQKYSQSNNKQSM-NLDYKNESSYISQQSQQSGVKDNSQ 1251 Query: 1572 LDNTMNKELL 1581 LD + E L Sbjct: 1252 LDQSSGWERL 1261 Score = 100 bits (239), Expect = 4e-19 Identities = 171/909 (18%), Positives = 384/909 (42%), Gaps = 102/909 (11%) Query: 306 EKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKL-------ATMGTESKA 358 E +++ + L N +L + E + Q+RQ ++LE +L + E + Sbjct: 397 EYQQLQREKELYDRNYKKLNDEYEREKEFVQQLRQDKRDLERELDQEKQVIRELKVEFER 456 Query: 359 VSSPSKKGSPLISR-----KSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMV 413 + + L+ + K+ + + + QL + L ++ D + E+ E + Sbjct: 457 MDVSKQNLDSLLQKFKQEQKNQQQSQQHNPNQGQQLMMDQLRKEND--LLTKEVQTTEGL 514 Query: 414 IQSLNKDLVDKE---YVISEKDTXXXXXXXXXXGKDTL-----------IAQLQLEHQQH 459 I+S+ ++L +K+ Y + ++ K+ IAQL+ E +Q+ Sbjct: 515 IKSIKRELGEKDRDNYELKQQKRLLNDQLSELAQKNANLDSQIKLKLQDIAQLEQEVEQY 574 Query: 460 MEGPSLIHVGTNT----------EDVNEIAKVQEQLKQELNDEIKDVNV--KDLIEKLKS 507 S + + + E V E+ +Q+Q L +I D+ + L EKLK Sbjct: 575 KREQSKMRLNQQSILEQKQKIENETVGELKLLQQQ-NNSLKLQISDLGIFNSQLEEKLKI 633 Query: 508 AEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHL 567 A+E + + E D N ++ +S+ K +Q N + D + LT E+ L Sbjct: 634 AQELLNEQRLENDKLQMN-LRQQSDETFKYQQ------NVLRNKDKEMDYYNLTHEIERL 686 Query: 568 SQKVAELEEEKGNLQLHLVDYDS--GRMIESDVYKKMIEMENLAETR--LKAISLLESQK 623 + ++ EK Q + +S + + + ++ E + E R + I+ L++ Sbjct: 687 RDQERKILIEKERFQSENLKLESVINQQTKQMEFLNKLKEEAMKEARELRQMINGLKTND 746 Query: 624 FDLVQELHILQQKYDEVEDKLADIS-QLQ-----SDQVCSEIKSVHLEEQIDALSASKKE 677 ++ L +K + E L DI+ QLQ S+++ +E+ + QI +L K + Sbjct: 747 HEIKNTSIKLSEKVNNYEMSLQDINEQLQKEISRSNKLYNEL--TESQSQISSLKLQKTD 804 Query: 678 LALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLA 737 I LKL + LE KE+++ +LQ + + + D+ + + +++E L Sbjct: 805 YENQIRQLKL-------LCESLEKQKEELLQRLQQ--KNSTKIEDERQVLQLRELNENLE 855 Query: 738 -KINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLE 796 K+N + IQ + +++ DL + ++++L + + L++ I M + ++ Sbjct: 856 DKVNQYSEQNIQ----LKRSLEQLDLERDEVQNQLDEVRETNISLQQQIKQMNN---EIQ 908 Query: 797 RKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKE--LQKK 854 ++ +L + ++ Y E++L D++ + Q L+ E++N + LQ K Sbjct: 909 KQQSKLSEVSTKGERGYEAAQQLEEKL---------RDQIYKNQKLQNENDNVKYTLQIK 959 Query: 855 NQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEH 914 + E ++QI D Q N L++ +L + + Q Q L+ +K E Sbjct: 960 EKEFHEMKSDIQILSKDNQSLNNQLIKSVQEKELQQQQIQFLQQQEIRLKEQIKMFDMEM 1019 Query: 915 QTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENL 974 L + + + N ++ +I+ ++ ++E+ ++ +LE Q +K ++N Sbjct: 1020 HDLQLNYSEVCAE-----NQRLTVSIQQ---ISLQHEEVLQRGVELEKQEDFFKVQMQNA 1071 Query: 975 NMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINN 1034 + E+ ++ L+ ++ +++ +S +Y E+ I E+ K L ++ ++ Sbjct: 1072 SKR-EDQYQIQLQQYEREIERLNRKSEEY-ERQIRELLKDRDQLGKEFHSQRKISTGFQA 1129 Query: 1035 AQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQL-LDSKQHNEELQILVREQDDQIK 1093 AQ + ++ E + ++++++ QL + K+ NE Q++++E+ Q+ Sbjct: 1130 AQEDFNRQIAQLEREKQYIENANRDLQKQVDLKDAQLSWEQKRVNEMEQVIIQERQMQMN 1189 Query: 1094 ELKETKLTFEMNIPKTEGMIISSTIEPMS-DDANNVDXXXXXXXXXXXXLKVQEEEEFIQ 1152 L+E + + N + + +P +NN + Q ++ ++ Sbjct: 1190 TLQEIQQLKDQNEQLLQE--LEKAYQPQKYSQSNNKQSMNLDYKNESSYISQQSQQSGVK 1247 Query: 1153 ERSVLQEQS 1161 + S L + S Sbjct: 1248 DNSQLDQSS 1256 Score = 98.7 bits (235), Expect = 1e-18 Identities = 171/921 (18%), Positives = 389/921 (42%), Gaps = 78/921 (8%) Query: 704 EDIMNKLQNYIQENMDLTDKLE--KMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERD 761 E ++N L + L +LE K++A K +LL + E Q + + + + Sbjct: 32 ERLLNDLVKTTEGFQQLKKQLEETKINAAKFEQLLLPLKKENQRIVNENNQLHMTMIQIK 91 Query: 762 LYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQED 821 E +++ +K++S++ LE D ++ L +K + +E K +E + Sbjct: 92 ---EECDTKENKWRSQVRMLESE---RNDWKFILGQKNNAEKKLQEELFKKNNENNYSQS 145 Query: 822 ELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDM--------- 872 ++ L+D + +E++LL+++ ++++ +L E+ ++L+ + + Sbjct: 146 NQPDKTLKLVDQIQELERKLLQVQQDSRDNDNSKVLLEEKCKHLEFQIENREKEILRLKS 205 Query: 873 -------------QQHY-NALVEKANRT----DLAESESTKYQTQLRDLESNLKRITHE- 913 Q+H + +KA RT DL E+TK +L +L L+R + Sbjct: 206 KLDIQGTNIEKLAQEHILSEAQQKAQRTQTQLDLLTEENTKLNDELSNLRKELQRFRKKP 265 Query: 914 HQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIEN 973 Q K + E+ Q S I D+K N++ K I ++QLE + + ++ Sbjct: 266 SQPQNSSPNKSDKKNELNQIKQRLSVIEDEKEKNQEQFKKI--LSQLEYENSQLIEKVQQ 323 Query: 974 LNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYIN-EINKLNAL--LKQKDEEIIALNQ 1030 L E+L L ++ V QT +++ N + +K N + LK +E+ L Sbjct: 324 LQQQNEQLQLKALNA-EQVVSAYQTDKMVFSKAVNNLKSDKENTVQTLKSLEEDNQKLRF 382 Query: 1031 KINNAQVSYMSMVSDYESKLAQ---FTTKLENMEEEMQRVSKQLLDSKQHNEELQILVRE 1087 ++N S+Y+ + + + + +E +R + + +Q +L+ RE Sbjct: 383 QLNEMDDQLQIQKSEYQQLQREKELYDRNYKKLNDEYEREKEFVQQLRQDKRDLE---RE 439 Query: 1088 QDDQIKELKETKLTFE-MNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQE 1146 D + + ++E K+ FE M++ K + S ++ + N L + Sbjct: 440 LDQEKQVIRELKVEFERMDVSKQN---LDSLLQKFKQEQKNQQQSQQHNPNQGQQLMM-- 494 Query: 1147 EEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQL 1206 ++ +E +L ++ ++ ++ + + N EL + +Q+++L K L Sbjct: 495 -DQLRKENDLLTKEVQTTEGLIKSIKRELGEKDRDNYELKQQKRLLNDQLSELAQKNANL 553 Query: 1207 NTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFES 1266 +++ L +A+L + ++ ++ + L Q++ +T EL++ S Sbjct: 554 DSQIKLKLQDIAQLEQEVEQYKREQS-KMRLNQQSILEQKQKIENETVGELKLLQQQNNS 612 Query: 1267 KYEQLLD-SVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVIN-QIEILR 1324 Q+ D + +S EE KI +++ + Q DK + NL+++ + Q +LR Sbjct: 613 LKLQISDLGIFNSQLEEKLKIA--QELLNEQRLENDKLQ--MNLRQQSDETFKYQQNVLR 668 Query: 1325 SEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQ-LKKSSXX 1383 ++ + E + + E + ++ +S++N + + L K Sbjct: 669 NK-DKEMDYYNLTHEIERLRDQERKILIEKERFQSENLKLESVINQQTKQMEFLNKLKEE 727 Query: 1384 XXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVE 1443 +N + H+++ ++ +K + Y ++L N E +++++ Sbjct: 728 AMKEARELRQMINGLKTN----DHEIKNTSIKLSEKVNNYEMSLQDIN---EQLQKEISR 780 Query: 1444 YEKRIEDLTYEKESELAILRLKMHENANHYETMQ---KESEIERVKLIEELNVKITESVS 1500 K +LT E +S+++ L+L+ + N ++ + E ++ +L++ L K + + Sbjct: 781 SNKLYNELT-ESQSQISSLKLQKTDYENQIRQLKLLCESLEKQKEELLQRLQQKNSTKIE 839 Query: 1501 LNKQVA---ELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKH 1557 +QV ELN+ LE++V + +E L+ ++ DE+ N + VR ++ +Q+ Sbjct: 840 DERQVLQLRELNENLEDKVNQYSEQNIQLKRSLEQLDLERDEVQNQLDEVRETNISLQQQ 899 Query: 1558 VSFASDTKQGRDEQLDNTMNK 1578 + ++ Q + +L K Sbjct: 900 IKQMNNEIQKQQSKLSEVSTK 920 Score = 70.5 bits (165), Expect = 4e-10 Identities = 146/708 (20%), Positives = 295/708 (41%), Gaps = 69/708 (9%) Query: 892 ESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYE 951 ++T+ QL+ K + + L++ KKE + + E N + I+ K+ + K Sbjct: 40 KTTEGFQQLKKQLEETKINAAKFEQLLLPLKKENQRIVNENNQLHMTMIQIKEECDTKEN 99 Query: 952 KNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQS--PDYTEQYIN 1009 K V LE++ ++K + N N E+ K+ EL K+ + +QS PD T + ++ Sbjct: 100 KWRSQVRMLESERNDWKFILGQKN-NAEK--KLQEELFKKNNENNYSQSNQPDKTLKLVD 156 Query: 1010 EINKLNALLKQ-------KDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEE 1062 +I +L L Q D + L +K + + + + E ++ + +KL+ Sbjct: 157 QIQELERKLLQVQQDSRDNDNSKVLLEEKCKHLEFQ----IENREKEILRLKSKLDIQGT 212 Query: 1063 EMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEM-NIPKTEGMIISSTIEPM 1121 +++++++ + S+ + + + Q D + E + TKL E+ N+ K +P Sbjct: 213 NIEKLAQEHILSEAQQKAQR--TQTQLDLLTE-ENTKLNDELSNLRKELQRFRKKPSQPQ 269 Query: 1122 SDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKII-QLET 1180 + N D K E + Q SV++++ K QE + KI+ QLE Sbjct: 270 NSSPNKSD-------------KKNELNQIKQRLSVIEDEKEKN----QEQFKKILSQLEY 312 Query: 1181 LNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWK 1240 N++L Q+Q QL+ L+ LN E ++S + S AV+ + E Sbjct: 313 ENSQLIEKVQQLQQQNEQLQ--LKALNAEQ--VVSAYQTDKMVFSKAVNNLKSD-KENTV 367 Query: 1241 QHLAQREADFQKTEHELRV---QLSAFESKYEQLL--DSVQSSTQEETNKIVTMEQVTSL 1295 Q L E D QK +L QL +S+Y+QL + ++ N E+ + Sbjct: 368 QTLKSLEEDNQKLRFQLNEMDDQLQIQKSEYQQLQREKELYDRNYKKLNDEYEREK-EFV 426 Query: 1296 QNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTE 1355 Q QDK + R L ++ VI ++++ E E V+ +++ Sbjct: 427 QQLRQDKRDLERELDQE-KQVIRELKV---EFERMDVSKQNLDSLLQKFKQEQKNQQQSQ 482 Query: 1356 NQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSE 1415 + Q Q+ + + +EN L K + + + EL Q L + + Sbjct: 483 QHNPNQGQQLMMDQLRKENDLLTKEVQTTEGLIKSIKRELGEKDRDNYELKQQKRLLNDQ 542 Query: 1416 IYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYET 1475 + + L Q+N ++ + ++ ++E + + E + +RL + Sbjct: 543 LSE--------LAQKNANLDSQIKLKLQDIAQLEQEVEQYKREQSKMRLNQQSILEQKQK 594 Query: 1476 MQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEM--QTALENQEIE- 1532 ++ E+ + +KL+++ N + +S + N LEE++ E+ + LEN +++ Sbjct: 595 IENET-VGELKLLQQQNNSLKLQIS---DLGIFNSQLEEKLKIAQELLNEQRLENDKLQM 650 Query: 1533 -IVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKE 1579 + +DE Q V + K + + + ++ RD++ + KE Sbjct: 651 NLRQQSDETFKYQQNVLRNKDKEMDYYNLTHEIERLRDQERKILIEKE 698 >UniRef50_Q86KX8 Cluster: Similar to Dictyostelium discoideum (Slime mold). Interaptin; n=2; Dictyostelium discoideum|Rep: Similar to Dictyostelium discoideum (Slime mold). Interaptin - Dictyostelium discoideum (Slime mold) Length = 1781 Score = 143 bits (346), Expect = 4e-32 Identities = 281/1457 (19%), Positives = 617/1457 (42%), Gaps = 140/1457 (9%) Query: 233 KDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQEL---EQXXXXXXXXX 289 +DE + L K I+ K + + + K+ + E+ E +K+ EL E+ Sbjct: 13 EDENEDLKKRIKQKAQQFDNQADVLKVTQKTATELKNEKNKILSELKLVEEKFNNGQIEI 72 Query: 290 XXXXXLAKQSI---EPSCEEKTEIE-EKGSLEIANMTEL-------TKKIEL-LEHLNCQ 337 + KQ+ + CE +++ EKG+LE + E+ K+IE+ E L Sbjct: 73 KKLQEILKQTKTNHQKVCELIDQLKVEKGNLEKQHQKEMREFEDKTNKQIEIQTEKLEKL 132 Query: 338 IRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQD 397 I +T+K L + + + + +K+ + + + KM+ QL + + Sbjct: 133 INETDK-LRCDKSNLEVRIVHLENSNKENKSYLLQSN--KEMGKMEIEIQQLQEQLTDSK 189 Query: 398 TDKKINKNEIAKLEMVIQSLN-------KDLVDKEYVIS---EKDTXXXXXXXXXXGKDT 447 + +++I +++IQ L K+L + ++ + EK+ T Sbjct: 190 EQESNQRSKIENKDIMIQQLRDKQQQYEKELRELQHQFNADNEKNQQIIDIQSEEISTST 249 Query: 448 LIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLK-QELNDEIKDVNVK--DLIEK 504 LI +LE + L ++ +EI + Q++ +L D N + LI + Sbjct: 250 LI-MTELEEKLEFVSDKLKSEQEKLKE-SEILIMDLQIQVSDLQSTSDDDNERYQSLISE 307 Query: 505 LKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFS-KVSDSNKEIVRLTEE 563 + + ++QLN EI+ KN ++ K + ++ K +++ +++ +K++ L + Sbjct: 308 YQENLKSVSQLNKEINEKLKNE---RTESKSLIDKISKENNDYQILITEQDKDLKDLKSQ 364 Query: 564 LHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKK-MIEMENLAETRLKAISLLESQ 622 L S ++L ++ L L ++Y+ + +++ + IE + L+ + L+ Q Sbjct: 365 LDTKSNNYSKLLDD---LSLSKLNYNKLNLEFNNISNEYQIEKQQLSFDFNELKKKLDDQ 421 Query: 623 KFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVI 682 + +L Q+ +E+ DK +I L SD K +QI+ ++ +L + + Sbjct: 422 IERNSNQQSLLTQRINEIIDKQKEIDNLNSDLQSLNDKQSDSNDQINTITNENNDLKIKL 481 Query: 683 ENL--------------KLDKEQLYGTIKDLENDKEDIMNKLQNYIQE-NMDLTDKLEKM 727 EN K + E LY I++L + +D + + +N I++ +D ++ L K Sbjct: 482 ENSILLISNHQDKLTTNKKELESLYSIIENLNSTHQDQLKEKENQIEQMKLDQSESLNKF 541 Query: 728 SAEKISEL---LAKINHEEQS------KIQTQFGIDAKI-QERDLYIENIESELSKYKSR 777 EKI+ L + IN E+ S Q KI +++ + + S + + Sbjct: 542 Q-EKITTLNHTIVNINSEKDSLNCLINDYSEQINELNKINNQKNQENQQLLSSIREDCQT 600 Query: 778 ICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVV 837 I +L+ +I ++D SL + + + LQ Q + ++ EL N+ + + V Sbjct: 601 INQLKSTIKSLQDESNSLSTEIEAI--KLQLNQLSTITIPEKDQELSNKERTIQEFQ--V 656 Query: 838 EKQLLEIEHENKELQKKNQILLEENQNLQI-SLSD-MQQHYNALVEKANRTDLAESESTK 895 + Q L+ + +L + +NQ++ I SL++ + Q + ++K + + Sbjct: 657 KTQQLKQTIQQNQLTINQHLTTIDNQSVDINSLNEKLVQLNDESIKKQQSIHSLSLQVIE 716 Query: 896 YQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIE 955 +L + + + L + + + +DL + Q++ D L +K Sbjct: 717 LNKKLSEKDDQYNQSLESIDQLTSELQLKQDDLNRQ-QEQLQKNSIDIDQLFDKINLGKS 775 Query: 956 YVTQLEAQLQEYKNNIENLNMNVEE-LNKMN-LELIDKHVQKQQTQSPDYTEQYINEINK 1013 +L + Q +N + NL ++++ +N N +L ++K Q E+ N + Sbjct: 776 NFDELNQRYQVEQNQLFNLKQDLQQSINLFNESKLYTTQLEKSIEQVKRVNEEQSNHQGE 835 Query: 1014 LNALLKQKDEEIIALNQKINNAQVSYMSMVSD---YESKLAQFTTKLENMEEEMQRVSKQ 1070 L LL ++ + L + N++ + D Y +++ Q +L +E +Q Sbjct: 836 LTILLDEERYKCQTLKMDLENSKQINQNQSDDLNFYNNQIEQLKQQLSESKELVQECKLS 895 Query: 1071 LLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMS--DDANNV 1128 + ++ ELQ+ ++E ++ ++ +ET + + + K + +E + +N++ Sbjct: 896 ISQFEKTVIELQLEIKELSNEKQQYQETCQSLSLKLSKLNDQ-SNDQLEQIQQLQSSNSL 954 Query: 1129 DXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKI-IQLETLNTELTG 1187 D ++ ++ + E S L+ Q E E +K+ +++E +LT Sbjct: 955 DLQNSQN-------QISLLQDSLNETSDLKSQLQCQLNESNEIISKLELKIEENQNQLTE 1007 Query: 1188 HDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQRE 1247 ++ Q +Q L++ ++ L+ +D+ +I +L +Q L+ + Sbjct: 1008 FELKIQSLSSQYNQDLQEQIEQSKMLIDEKQSCIQLQEMEIDKNNHKIQQL-QQDLSTSD 1066 Query: 1248 ADFQKTEHELRV---QLSAFESKYEQLLDSVQSS------TQEETNK-----IVTMEQVT 1293 Q+ + +L++ ++ E Q S++ S Q+ET+K + +T Sbjct: 1067 YKIQQLQIDLQIDKDEIIKLEETISQRNQSIKESLVKCNDLQDETSKLNDNLLQLNSTIT 1126 Query: 1294 SLQNKLQDKEEHLRNLQEKYADV---INQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXX 1350 Q+++ + E++++LQ + + ++Q++ SE D+ Sbjct: 1127 DYQSQITESNENVQSLQNEKNQLQLELDQLKQRISEQHDDITLLNSIEFELNRKISNYQS 1186 Query: 1351 DLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLE 1410 D++ + + K +Q NE+N QL+ V+ + +LEL ++ Sbjct: 1187 DIKEYDNNIKVIQ-------NEKN-QLQLELDQLKQVLSDKQDGVSTLNSTLLELNKKIN 1238 Query: 1411 LKDSEIYQKTHEYTITLTQRND---EFENVRQQLVEYEKRIEDL--------TYEKESEL 1459 EI Y + ++N EF+ ++QQL E + I L + +K S+ Sbjct: 1239 DYQMEINDSQSNYQELIDEKNQLQLEFDRLKQQLFEKQDEISTLKQDIQLFNSNKKNSDS 1298 Query: 1460 AILRLKMH----ENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEE 1515 +I +L H ++ N + +E+ER KL ++ ++ E+V L KQ + N++ ++ Sbjct: 1299 SIDQLSNHVTELKSKNQQLLLDLSNELERNKLQNDMITQLKENVELEKQNSFENQSKSDD 1358 Query: 1516 V-AKTNEMQTALENQEIEIVTLN-DEITNLQNMVRASSSKIQKHVSF--ASDTKQGRDEQ 1571 + +K +EM QE + VT N E TN + ++ ++++ + F S+T ++ Sbjct: 1359 IKSKLDEM-----IQEFKEVTQNLQEKTNENSNLQCKLDQLEQEIKFEKESNTHLRKEND 1413 Query: 1572 LDNTMNKELLDAVPRAE 1588 D + K+L ++ + E Sbjct: 1414 KDTLVIKQLEQSISQLE 1430 Score = 138 bits (333), Expect = 2e-30 Identities = 294/1540 (19%), Positives = 654/1540 (42%), Gaps = 168/1540 (10%) Query: 144 VTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINE-KDQIIEAKNKATTXXXXXXXX 202 + HL N+ KE + L +M ME I LQE++ + K+Q ++K Sbjct: 150 IVHLENSNKENKSYLLQSNKEMGKMEIEIQQLQEQLTDSKEQESNQRSKIEN-----KDI 204 Query: 203 XXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSL--EEANKLL 260 + ++++ ++Q F A +EK + + DI+S+++ S+L E + L Sbjct: 205 MIQQLRDKQQQYEKELRELQHQFNA-----DNEKNQQIIDIQSEEISTSTLIMTELEEKL 259 Query: 261 EAARFEISLEHSKLAQ-------------ELEQXXXXXXXXXXXXXXLAKQSIEPSCEEK 307 E ++ E KL + +L+ +++++ + Sbjct: 260 EFVSDKLKSEQEKLKESEILIMDLQIQVSDLQSTSDDDNERYQSLISEYQENLKSVSQLN 319 Query: 308 TEIEEKGSLEIANMTELTKKIELLEH-LNCQIRQTNKELENKLATMGTESKAVS------ 360 EI EK E L KI + I + +K+L++ + + T+S S Sbjct: 320 KEINEKLKNERTESKSLIDKISKENNDYQILITEQDKDLKDLKSQLDTKSNNYSKLLDDL 379 Query: 361 SPSKKGSPLISRKSGRNTASKMKSPWSQLSSE--TLNQDTDKKINKNEIAKLEMVIQSLN 418 S SK ++ + N +++ + QLS + L + D +I +N + ++ Q +N Sbjct: 380 SLSKLNYNKLNLEF-NNISNEYQIEKQQLSFDFNELKKKLDDQIERNS-NQQSLLTQRIN 437 Query: 419 KDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQ---HMEGPSLI------HVG 469 +++DK+ I ++ + I + E+ +E L+ + Sbjct: 438 -EIIDKQKEIDNLNSDLQSLNDKQSDSNDQINTITNENNDLKIKLENSILLISNHQDKLT 496 Query: 470 TNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLK-SAEEQITQLNDEIDAANKNMIK 528 TN +++ + + E L D++K+ ++ IE++K E + + ++I N ++ Sbjct: 497 TNKKELESLYSIIENLNSTHQDQLKE--KENQIEQMKLDQSESLNKFQEKITTLNHTIVN 554 Query: 529 V---KSNHKLKLKQMQKTIDNFSKVSD----SNKEIVRLTEE----LHHLSQKVAELEEE 577 + K + + + I+ +K+++ N++++ E ++ L + L++E Sbjct: 555 INSEKDSLNCLINDYSEQINELNKINNQKNQENQQLLSSIREDCQTINQLKSTIKSLQDE 614 Query: 578 KGNL--QLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQ 635 +L ++ + ++ + +K E+ N T + + K + Q + Q Sbjct: 615 SNSLSTEIEAIKLQLNQLSTITIPEKDQELSNKERTIQEFQVKTQQLKQTIQQNQLTINQ 674 Query: 636 KYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGT 695 ++++ DI+ L V +S+ ++ I +LS EL + Q + Sbjct: 675 HLTTIDNQSVDINSLNEKLVQLNDESIKKQQSIHSLSLQVIELNKKLSEKDDQYNQSLES 734 Query: 696 IKDLEND---KEDIMNKLQNYIQEN-MDLTDKLEKMSAEK--ISELLAKINHEEQSKIQT 749 I L ++ K+D +N+ Q +Q+N +D+ +K++ K EL + E+ Sbjct: 735 IDQLTSELQLKQDDLNRQQEQLQKNSIDIDQLFDKINLGKSNFDELNQRYQVEQNQLFNL 794 Query: 750 QFGIDAKI---QERDLYIENIESELSKYK----SRICRLEESIAVMEDRRYSLERKADQL 802 + + I E LY +E + + K + E ++++ RY + L Sbjct: 795 KQDLQQSINLFNESKLYTTQLEKSIEQVKRVNEEQSNHQGELTILLDEERYKCQTLKMDL 854 Query: 803 GSYLQEKQKAYSE---YTIQEDELVNRLA---VLMDHDRV----VEKQLLEIEHENKELQ 852 + Q Q + Y Q ++L +L+ L+ ++ EK ++E++ E KEL Sbjct: 855 ENSKQINQNQSDDLNFYNNQIEQLKQQLSESKELVQECKLSISQFEKTVIELQLEIKELS 914 Query: 853 KKNQILLEENQNLQISLSDMQQHYNALVEK------ANRTDLAESES--TKYQTQLR--- 901 + Q E Q+L + LS + N +E+ +N DL S++ + Q L Sbjct: 915 NEKQQYQETCQSLSLKLSKLNDQSNDQLEQIQQLQSSNSLDLQNSQNQISLLQDSLNETS 974 Query: 902 DLESNLKRITHEHQTLIVQKKKEIEDLE---IEFNTQIES-AIRDKKVLNEKYEKNIEYV 957 DL+S L+ +E +I + + +IE+ + EF +I+S + + + L E+ E++ + Sbjct: 975 DLKSQLQCQLNESNEIISKLELKIEENQNQLTEFELKIQSLSSQYNQDLQEQIEQSKMLI 1034 Query: 958 TQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYI---NEINKL 1014 + ++ +Q + I+ N +++L + +L D +Q+ Q ++ I I++ Sbjct: 1035 DEKQSCIQLQEMEIDKNNHKIQQL-QQDLSTSDYKIQQLQIDLQIDKDEIIKLEETISQR 1093 Query: 1015 NALLKQ---KDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEE-------- 1063 N +K+ K ++ K+N+ + S ++DY+S++ + +++++ E Sbjct: 1094 NQSIKESLVKCNDLQDETSKLNDNLLQLNSTITDYQSQITESNENVQSLQNEKNQLQLEL 1153 Query: 1064 ---MQRVSKQ-----LLDSKQH--NEEL---QILVREQDDQIKELKETKLTFEMNIPKTE 1110 QR+S+Q LL+S + N ++ Q ++E D+ IK ++ K ++ + + + Sbjct: 1154 DQLKQRISEQHDDITLLNSIEFELNRKISNYQSDIKEYDNNIKVIQNEKNQLQLELDQLK 1213 Query: 1111 GMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEE--EEFIQERSVLQEQSAKLNTEL 1168 ++S + +S + + + + +E I E++ LQ + +L +L Sbjct: 1214 -QVLSDKQDGVSTLNSTLLELNKKINDYQMEINDSQSNYQELIDEKNQLQLEFDRLKQQL 1272 Query: 1169 QECYTKIIQLETLNTELTGHDVVNQE-QINQLKSKLEQLNTENDNLLSTVA-EL-RSSIS 1225 E +I L+ + +L + N + I+QL + + +L ++N LL ++ EL R+ + Sbjct: 1273 FEKQDEISTLKQ-DIQLFNSNKKNSDSSIDQLSNHVTELKSKNQQLLLDLSNELERNKLQ 1331 Query: 1226 SAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNK 1285 + + + E EL KQ+ + Q +++ +L +++++ ++Q T E +N Sbjct: 1332 NDMITQLKENVELEKQNSFEN----QSKSDDIKSKLDEMIQEFKEVTQNLQEKTNENSNL 1387 Query: 1286 IVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIE-----------DEKVAF 1334 ++Q+ ++ HLR +K VI Q+E S++E E+ Sbjct: 1388 QCKLDQLEQEIKFEKESNTHLRKENDKDTLVIKQLEQSISQLEHLHSQQTENYLKERELI 1447 Query: 1335 XXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXR 1394 L+++ +Q ++S+ +++ +L K Sbjct: 1448 QQQHQDEKQSSIQSTHQLKSKFDEKQQQYDESLEKLSQSKQELNKLKQEFDLNILVIQKL 1507 Query: 1395 VNDAEAKV---LELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDL 1451 +D +++ L+L LE + + Q++ E TL Q + +++QQ I+ L Sbjct: 1508 QDDKQSQSDSNLQLKSNLEEQQLQ-NQESIEKISTLQQ---QVNHLQQQFNINTLEIQKL 1563 Query: 1452 TYEKE---SELAILRLKMHENANHY-ETMQKESEIERVKLIEELNVKITESVSLNKQVAE 1507 EK+ + L+ K E Y E+++K ++++ K ++L K+ S + N+Q+ E Sbjct: 1564 QDEKQLSIESIHQLKSKFDEKQQQYNESIEKSNDLQ--KQSDQLQQKLENSTNENQQLQE 1621 Query: 1508 LNKALEEE----VAKTNEMQTALENQEIEIVTLNDEITNL 1543 ++ E V + + ++ + ++ +DE+T L Sbjct: 1622 KISTIQLEQINNVQQDDSKDLIIKQLQQSLLDKDDELTTL 1661 Score = 134 bits (324), Expect = 2e-29 Identities = 244/1138 (21%), Positives = 502/1138 (44%), Gaps = 138/1138 (12%) Query: 312 EKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLIS 371 EK SL + + +++I L +N Q Q N++L L+++ + + ++ L Sbjct: 558 EKDSLNCL-INDYSEQINELNKINNQKNQENQQL---LSSIREDCQTINQLKSTIKSLQD 613 Query: 372 RKSGRNTASK-MKSPWSQLSSETLNQDTDKKINKNE-IAKLEMVIQSLNKDLVDKEYVIS 429 + +T + +K +QLS+ T+ + + NK I + ++ Q L + + + I+ Sbjct: 614 ESNSLSTEIEAIKLQLNQLSTITIPEKDQELSNKERTIQEFQVKTQQLKQTIQQNQLTIN 673 Query: 430 EKDTXXXXXXXXXXGKDTLIAQLQ---LEHQQHMEGPSLIHVGTNT------EDVNEIAK 480 + T + + QL ++ QQ + SL + N + N+ + Sbjct: 674 QHLTTIDNQSVDINSLNEKLVQLNDESIKKQQSIHSLSLQVIELNKKLSEKDDQYNQSLE 733 Query: 481 VQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNM------IKVKSNHK 534 +QL EL + D+N + E+L+ I QL D+I+ N +V+ N Sbjct: 734 SIDQLTSELQLKQDDLNRQQ--EQLQKNSIDIDQLFDKINLGKSNFDELNQRYQVEQNQL 791 Query: 535 LKLKQ-MQKTIDNFSK-------VSDSNKEIVRLTEEL-HHLSQKVAELEEEKGNLQLHL 585 LKQ +Q++I+ F++ + S +++ R+ EE +H + L+EE+ Q Sbjct: 792 FNLKQDLQQSINLFNESKLYTTQLEKSIEQVKRVNEEQSNHQGELTILLDEERYKCQTLK 851 Query: 586 VDYDSGRMI---ESD---VYKKMIEM--ENLAETR------LKAISLLESQKFDL---VQ 628 +D ++ + I +SD Y IE + L+E++ +IS E +L ++ Sbjct: 852 MDLENSKQINQNQSDDLNFYNNQIEQLKQQLSESKELVQECKLSISQFEKTVIELQLEIK 911 Query: 629 ELHILQQKYDEVEDKLA-DISQL--QSDQVCSEIKSVHLEEQIDALSASKKELALVIENL 685 EL +Q+Y E L+ +S+L QS+ +I+ + +D L S+ +++L+ ++L Sbjct: 912 ELSNEKQQYQETCQSLSLKLSKLNDQSNDQLEQIQQLQSSNSLD-LQNSQNQISLLQDSL 970 Query: 686 KLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMD-LTD---KLEKMSAEKISELLAKINH 741 + L ++ N+ +I++KL+ I+EN + LT+ K++ +S++ +L +I Sbjct: 971 N-ETSDLKSQLQCQLNESNEIISKLELKIEENQNQLTEFELKIQSLSSQYNQDLQEQIEQ 1029 Query: 742 ------EEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSL 795 E+QS IQ Q + +I + + I+ ++ +LS +I +L+ + + +D L Sbjct: 1030 SKMLIDEKQSCIQLQ---EMEIDKNNHKIQQLQQDLSTSDYKIQQLQIDLQIDKDEIIKL 1086 Query: 796 ERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQ-KK 854 E Q ++E ++ + +L + L L + Q+ E + LQ +K Sbjct: 1087 EETISQRNQSIKESLVKCNDLQDETSKLNDNLLQLNSTITDYQSQITESNENVQSLQNEK 1146 Query: 855 NQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEH 914 NQ+ LE +Q L+ +S+ QH + + + +L S YQ+ +++ ++N+K I +E Sbjct: 1147 NQLQLELDQ-LKQRISE--QHDDITLLNSIEFELNRKISN-YQSDIKEYDNNIKVIQNEK 1202 Query: 915 QTL---IVQKKKEIEDLE----------IEFNTQI---ESAIRD-----KKVLNEKYEKN 953 L + Q K+ + D + +E N +I + I D +++++EK + Sbjct: 1203 NQLQLELDQLKQVLSDKQDGVSTLNSTLLELNKKINDYQMEINDSQSNYQELIDEKNQLQ 1262 Query: 954 IEYVTQLEAQLQEYKNNIENLNMNVE--ELNKMN----LELIDKHVQKQQTQSPDYTEQY 1007 +E+ +L+ QL E ++ I L +++ NK N ++ + HV + ++++ Sbjct: 1263 LEF-DRLKQQLFEKQDEISTLKQDIQLFNSNKKNSDSSIDQLSNHVTELKSKNQQLLLDL 1321 Query: 1008 INEI--NKL-NALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEM 1064 NE+ NKL N ++ Q E + Q Q + S + + +F +N++E+ Sbjct: 1322 SNELERNKLQNDMITQLKENVELEKQNSFENQSKSDDIKSKLDEMIQEFKEVTQNLQEKT 1381 Query: 1065 QRVSK------QLLDSKQHNEELQILVREQDDQ----IKELKETKLTFE-MNIPKTEGMI 1113 S QL + +E +R+++D+ IK+L+++ E ++ +TE + Sbjct: 1382 NENSNLQCKLDQLEQEIKFEKESNTHLRKENDKDTLVIKQLEQSISQLEHLHSQQTENYL 1441 Query: 1114 IS-STIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECY 1172 I+ D K Q+ +E +++ S +++ KL E Sbjct: 1442 KERELIQQQHQDEKQSSIQSTHQLKSKFDEKQQQYDESLEKLSQSKQELNKLKQEFDLNI 1501 Query: 1173 TKIIQLET-----------LNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELR 1221 I +L+ L + L + NQE I ++ + +Q+N E++ Sbjct: 1502 LVIQKLQDDKQSQSDSNLQLKSNLEEQQLQNQESIEKISTLQQQVNHLQQQFNINTLEIQ 1561 Query: 1222 S-------SISSAVDQRG-FEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLD 1273 SI S + F+ + ++ D QK +L+ +L ++ +QL + Sbjct: 1562 KLQDEKQLSIESIHQLKSKFDEKQQQYNESIEKSNDLQKQSDQLQQKLENSTNENQQLQE 1621 Query: 1274 SVQSSTQEETNKIVTMEQ----VTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEI 1327 + + E+ N + + + LQ L DK++ L L E Y +I + +I +I Sbjct: 1622 KISTIQLEQINNVQQDDSKDLIIKQLQQSLLDKDDELTTLFENYEQLIKKNKIDEKKI 1679 Score = 101 bits (242), Expect = 2e-19 Identities = 161/811 (19%), Positives = 337/811 (41%), Gaps = 56/811 (6%) Query: 144 VTHLSNTIKEKDNALSVLQVKMKIMETTI-LDLQEKINEKDQIIEAKNKATTXXXXXXXX 202 ++ L I+E N L+ ++K++ + + DLQE+I + +I+ K Sbjct: 991 ISKLELKIEENQNQLTEFELKIQSLSSQYNQDLQEQIEQSKMLIDEKQSCIQLQEMEIDK 1050 Query: 203 XXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRIS-SLEEANKLLE 261 +D K+Q+ I ++ + KDE +L + I ++ I SL + N L + Sbjct: 1051 NNHKIQQLQQDLSTSDYKIQQLQIDLQID-KDEIIKLEETISQRNQSIKESLVKCNDLQD 1109 Query: 262 AARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANM 321 E SKL L Q + ++++ EK +++ + + Sbjct: 1110 --------ETSKLNDNLLQLNSTITDYQSQITE-SNENVQSLQNEKNQLQLELDQLKQRI 1160 Query: 322 TELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASK 381 +E I LL + ++ + ++ + K + + +K + + S Sbjct: 1161 SEQHDDITLLNSIEFELNRKISNYQSDIKEYDNNIKVIQN--EKNQLQLELDQLKQVLSD 1218 Query: 382 MKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVIS-EKDTXXXXXXX 440 + S L+S L + +KKIN ++ + QS ++L+D++ + E D Sbjct: 1219 KQDGVSTLNSTLL--ELNKKINDYQMEINDS--QSNYQELIDEKNQLQLEFDRLKQQLFE 1274 Query: 441 XXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKD 500 TL +QL + S I +N V E+ +QL +L++E+ Sbjct: 1275 KQDEISTLKQDIQLFNSNKKNSDSSIDQLSN--HVTELKSKNQQLLLDLSNEL------- 1325 Query: 501 LIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRL 560 E+ K + ITQL + ++ +N + +S ++ + I F +V+ + +E Sbjct: 1326 --ERNKLQNDMITQLKENVELEKQNSFENQSKSDDIKSKLDEMIQEFKEVTQNLQE---K 1380 Query: 561 TEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLE 620 T E +L K+ +LE+E + +S + + K + ++ L ++ + L Sbjct: 1381 TNENSNLQCKLDQLEQEIK------FEKESNTHLRKENDKDTLVIKQLEQSISQLEHLHS 1434 Query: 621 SQKFDLVQELHILQQKY-DEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELA 679 Q + ++E ++QQ++ DE + + QL+S + K +E ++ LS SK+EL Sbjct: 1435 QQTENYLKERELIQQQHQDEKQSSIQSTHQLKSK---FDEKQQQYDESLEKLSQSKQEL- 1490 Query: 680 LVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKI 739 LK + + I+ L++DK+ + ++ N++ + S EKIS L ++ Sbjct: 1491 ---NKLKQEFDLNILVIQKLQDDKQS-QSDSNLQLKSNLEEQQLQNQESIEKISTLQQQV 1546 Query: 740 NHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKA 799 NH +Q I E+ L IE+I SK+ + + ESI D + ++ Sbjct: 1547 NHLQQQFNINTLEIQKLQDEKQLSIESIHQLKSKFDEKQQQYNESIEKSNDLQKQSDQLQ 1606 Query: 800 DQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVV---EKQLLEIEHENKELQKKNQ 856 +L + E Q+ + + + E +N + D ++ ++ LL+ + E L + + Sbjct: 1607 QKLENSTNENQQLQEKISTIQLEQINNVQQDDSKDLIIKQLQQSLLDKDDELTTLFENYE 1666 Query: 857 ILLEENQNLQISLSDMQQHYNALVEKAN-----RTDLAESESTKYQTQLRDLESNLKRIT 911 L+++N+ + + ++ N++ N + L E ++K S L+++ Sbjct: 1667 QLIKKNKIDEKKIRTLESKLNSINSTVNHNLPIKKPLEEVSNSKINIISSSSPSKLEQLQ 1726 Query: 912 HEHQTLIVQKKKEIEDLEIEFNTQIESAIRD 942 Q+K I ++ +I+ +D Sbjct: 1727 TVSNQQSQQQKPTINKPPLQIKRKIDFNSQD 1757 Score = 83.8 bits (198), Expect = 4e-14 Identities = 145/695 (20%), Positives = 291/695 (41%), Gaps = 74/695 (10%) Query: 900 LRDLESNLK-RITHEHQTLIVQKK--KEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEY 956 L D +LK RI + Q Q K + E + + + K++ EK+ Sbjct: 12 LEDENEDLKKRIKQKAQQFDNQADVLKVTQKTATELKNEKNKILSELKLVEEKFNNGQIE 71 Query: 957 VTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYIN-EINKLN 1015 + +L+ L++ K N + + +++L K+ ++K QK+ + D T + I + KL Sbjct: 72 IKKLQEILKQTKTNHQKVCELIDQL-KVEKGNLEKQHQKEMREFEDKTNKQIEIQTEKLE 130 Query: 1016 ALLKQKDEEIIALNQKINNAQVSYMSMV-SDYESK--LAQFTTKLENMEEEMQRVSKQLL 1072 L+ + D+ L +N +V + + S+ E+K L Q ++ ME E+Q++ +QL Sbjct: 131 KLINETDK----LRCDKSNLEVRIVHLENSNKENKSYLLQSNKEMGKMEIEIQQLQEQLT 186 Query: 1073 DSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXX 1132 DSK+ + + +D I++L++ + +E + + + + + +D Sbjct: 187 DSKEQESNQRSKIENKDIMIQQLRDKQQQYEKELRELQHQFNADN----EKNQQIIDIQS 242 Query: 1133 XXXXXXXXXL-KVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVV 1191 + +++E+ EF+ ++ L+ + KL E +Q++ + + T D Sbjct: 243 EEISTSTLIMTELEEKLEFVSDK--LKSEQEKLKE--SEILIMDLQIQVSDLQSTSDDDN 298 Query: 1192 NQEQ--INQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREAD 1249 + Q I++ + L+ ++ N + + R+ S +D+ E + ++ + +++ D Sbjct: 299 ERYQSLISEYQENLKSVSQLNKEINEKLKNERTESKSLIDKISKENND-YQILITEQDKD 357 Query: 1250 FQKTEHELRVQLSAFESKYEQLLDSVQSSTQE------ETNKIVTMEQV---------TS 1294 + +L+ QL + Y +LLD + S E N I Q+ Sbjct: 358 LK----DLKSQLDTKSNNYSKLLDDLSLSKLNYNKLNLEFNNISNEYQIEKQQLSFDFNE 413 Query: 1295 LQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRT 1354 L+ KL D+ E N Q IN+I + EI D + + Sbjct: 414 LKKKLDDQIERNSNQQSLLTQRINEIIDKQKEI-DNLNSDLQSLNDKQSDSNDQINTITN 472 Query: 1355 ENQSYKQMQEQSILNINEENAQL---KKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLEL 1411 EN K E SIL I+ +L KK D + Q++L Sbjct: 473 ENNDLKIKLENSILLISNHQDKLTTNKKELESLYSIIENLNSTHQDQLKEKENQIEQMKL 532 Query: 1412 KDSEIYQKTHEYTITLTQR----NDEFENVRQQLVEYEKRIEDL-------TYEKESELA 1460 SE K E TL N E +++ + +Y ++I +L E + L+ Sbjct: 533 DQSESLNKFQEKITTLNHTIVNINSEKDSLNCLINDYSEQINELNKINNQKNQENQQLLS 592 Query: 1461 ILR---LKMHENANHYETMQKES-----EIERVKLIEELNVKITESV-SLNKQVAELNKA 1511 +R +++ + +++Q ES EIE +KL +LN T ++ +++++ + Sbjct: 593 SIREDCQTINQLKSTIKSLQDESNSLSTEIEAIKL--QLNQLSTITIPEKDQELSNKERT 650 Query: 1512 LEEEVAKTNEM-QTALENQEIEIVTLNDEITNLQN 1545 ++E KT ++ QT +NQ +T+N +T + N Sbjct: 651 IQEFQVKTQQLKQTIQQNQ----LTINQHLTTIDN 681 >UniRef50_A0DQ77 Cluster: Chromosome undetermined scaffold_6, whole genome shotgun sequence; n=2; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_6, whole genome shotgun sequence - Paramecium tetraurelia Length = 3126 Score = 143 bits (346), Expect = 4e-32 Identities = 296/1477 (20%), Positives = 626/1477 (42%), Gaps = 175/1477 (11%) Query: 174 DLQEKINE---KDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEA 230 DLQ+++NE ++ + AK K + ++Q+ + + + + Sbjct: 940 DLQKQLNELQKQNAELLAKLKTQKDTQMQYMSKLSQSSENLTNYEKQLQQQTQKYAELNQ 999 Query: 231 EWKDEKQR---LLKD-IESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXX 286 E+ KQ+ L K+ +SK + + + + + + +++ +L +++ Q Sbjct: 1000 EYIQFKQKYDQLQKESTQSKSAQSKEINQYQQKITQLQQQMNETSKQLKEKVNQLQSQLL 1059 Query: 287 XXXXXXXXLAKQSIE---PSCEEKT---EIEEKGSLEIANMTELTKKI-ELLEHLNCQIR 339 L KQ C +KT EI+ + + + E +++ E+ LN +I Sbjct: 1060 LEQEQCQILKKQQENFQRDFCMQKTQNGEIQNQTNTLRQQLIEKEQQLKEVQTILNTKI- 1118 Query: 340 QTNKELENKLATMGTE----SKAVSSPSKKGSPLISRKSGRNTA--SKMKSPWSQLSSET 393 Q ++LEN++ + + SK V S ++ + ++ ++ +++ S L + Sbjct: 1119 QVIQQLENQVKDVQVQNASTSKQVQSLNQIQVDNLKKQLQQDQLRINELNDQISNLQQKI 1178 Query: 394 LNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQ 453 + + K K+ IQS K L+ +Y K L QLQ Sbjct: 1179 FTLEQQLQAEKQNNIKITKEIQS-TKILIQNDYQQQTHQLEQENIDLQQKLKQ-LEQQLQ 1236 Query: 454 LEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQIT 513 E + +++ N VN++ QE N++I + N+K IE+LK E ++ Sbjct: 1237 KERENNIQIQQQFITIENNYQVNQVKSTQE------NEKIVN-NLKFQIEQLKLQNEDLS 1289 Query: 514 QLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAE 573 +IKV+SN+++++ M V + K+++ E+ + S ++ + Sbjct: 1290 S----------QIIKVRSNYEIQMSTMNTMTSQ--NVINLEKQLLFEKEQKENSSMRILQ 1337 Query: 574 LEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHIL 633 LE++ + Q H++ D E + +E +NL ++ + I LL Q+ D +E+ IL Sbjct: 1338 LEKQVADFQ-HIIKSDQTE--EYKIQLNQLENQNLKLSKERDILLLSKQRGD--EEIKIL 1392 Query: 634 QQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLY 693 + E+ ++ ++L+ + S K + EQI ++ ++ ++ + + ++ Sbjct: 1393 NVRISELSNQNTQ-NELELMNLRS--KQGNQMEQISKMTTLTQQTVILQQERQSQNNEMI 1449 Query: 694 GTIKDLENDKEDIMNKLQNY-IQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFG 752 + +E + +D ++ I + DL ++ ++ + E+L N + + + +F Sbjct: 1450 LMRQRMEKNIQDHEQQIAELRISFSRDLENQ-NMLNRKLQDEILNAQNLLQSERREREF- 1507 Query: 753 IDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKA 812 +Q+ + E + +L++ K L + I + + L+ + ++LG +Q + Sbjct: 1508 ----LQKSQSHSEQVIQQLNQDKQT---LHDQILKLNSQIQQLQMEINKLGF---NQQNS 1557 Query: 813 YSEYTIQEDELVNRLAVLMDHDRVVEKQL-LEIEHENKELQKKNQIL--LE-ENQNLQIS 868 E+ + + ++ + +DH + ++L EI+ N ++Q+ N + LE +NQNL+ Sbjct: 1558 KDEHNLFQQQITS-YTTQIDHLNINTQKLNKEIDRLNLQIQQMNVMQGDLECQNQNLKQQ 1616 Query: 869 LSDMQQHYNALVEKANRTDLAESESTKYQT--QLRDLESNLK----------RITHEHQT 916 LS + N +++ + ++ E S Y + Q++DL L+ R + Sbjct: 1617 LSLLTSQ-NQTIQQQSEINVIEIRSAAYDSEDQIQDLTQKLEQQIKETEKYQRAAFNNDQ 1675 Query: 917 LIVQKKKEIED-------LEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKN 969 L+ +K+I D ++ ++ QIE IR K EK++ + Q+ Q+Q Sbjct: 1676 LVQSLQKKISDENLQNQKIKQQYEIQIEELIR-KINEKEKFDSSTPPKAQIFPQIQNTHL 1734 Query: 970 NIEN--LNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNAL---------- 1017 EN L + +++ KM + + + KQQ + T++Y N N+ Sbjct: 1735 IQENEELLLKIDQYEKM-IRALQEEYYKQQGELQKLTKEYHNVTNQSEQTVVTITQYQQQ 1793 Query: 1018 ---LKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQR-VSKQLLD 1073 +K+K++ L Q+I + Q + + S Y+ ++ + TTK + + ++Q ++KQ+++ Sbjct: 1794 QDNIKKKEDLTKQLQQQIQDLQKKFETERSRYQDEINRLTTKNQELSNQLQNNLNKQIIE 1853 Query: 1074 SKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXX 1133 + N + QI + EQ+ Q +KET II + P+ N + Sbjct: 1854 -ENFNLKNQIQLLEQELQNTPIKET--------------IIYQSASPLKK--NEEEITKY 1896 Query: 1134 XXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQ 1193 L++ + + ++L++Q+ +L++ +I QL+ L +L + Q Sbjct: 1897 KQQANQLQLRMNQ---MASDYNLLEQQTELEKVQLEK---QIKQLQDLEQKLLNENNQQQ 1950 Query: 1194 EQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKT 1253 QI L+ +L+QL N +S EL + Q FEI +L +++ Sbjct: 1951 RQIEALQRQLQQLQMNRQNDMSQ--ELEFELKKLKSQ--FEITQL----------QYKQI 1996 Query: 1254 EHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKY 1313 + EL +Q + +Y L Q+ E +I+ EQ+ S + K Q+ E Sbjct: 1997 QEEL-IQAKSQAFQYRDELVDEQNQKNELNLRIIHYEQILS-ELKQQNNPE--------- 2045 Query: 1314 ADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQ---MQEQSILNI 1370 + +I + I++ +++D A L+ Y Q +Q+ I ++ Sbjct: 2046 STMIKETTIIKEQVQDP--ALIKQVNQLIDDNNSLRKQLQNLEADYIQKFRLQQLQIQDL 2103 Query: 1371 NEENAQLKKSSXXXXXXXXXXXXRV--NDAEAKVLELTHQLELKDSEIYQKTHEYTITLT 1428 N + Q + + ND A++ +L + E+ ++ Y + Sbjct: 2104 NNKINQNDEENYQKTTITEETTINTVSNDQSAEIRKLKDEKLFLQQELQKQQQLYKKQIE 2163 Query: 1429 QRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHEN---ANHYETMQKESEIERV 1485 Q +++E QQ Y+ I+ L KE + + + EN A + +Q E I R Sbjct: 2164 QITNDYEFRIQQ---YKLTIQQLKESKEIQTNDDQNLLKENQMLAEQIKHLQNELTISRA 2220 Query: 1486 KLIEELNVKITESVSLNK--QVAELNKALEEEVAKTNEM----QTALENQEIEIVTLNDE 1539 ++L S NK + + N+ L++++ + N++ Q L+N +I E Sbjct: 2221 SFQDQLQQNNQNSTEANKLKSLQKRNEDLDQQIEQQNKIIAQFQQQLQNIQIIYEEKEKE 2280 Query: 1540 ITNLQNMVRASSSKIQKHVSFASDTKQGR--DEQLDN 1574 + NL+ + +S++ K + Q R +EQL N Sbjct: 2281 LQNLKTNYQNLNSQLNKAPQLSEPENQSRIHNEQLIN 2317 Score = 133 bits (321), Expect = 4e-29 Identities = 268/1417 (18%), Positives = 588/1417 (41%), Gaps = 105/1417 (7%) Query: 220 KMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEE----ANKLLEAARFE---ISLEHS 272 +M++N E + + + +D+E++++ L++ A LL++ R E + S Sbjct: 1454 RMEKNIQDHEQQIAELRISFSRDLENQNMLNRKLQDEILNAQNLLQSERREREFLQKSQS 1513 Query: 273 KLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCE-EKTEIEEKGSLEIANM--TELTKKIE 329 Q ++Q L Q + E K ++ S + N+ ++T Sbjct: 1514 HSEQVIQQLNQDKQTLHDQILKLNSQIQQLQMEINKLGFNQQNSKDEHNLFQQQITSYTT 1573 Query: 330 LLEHLNCQIRQTNKELEN---KLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPW 386 ++HLN ++ NKE++ ++ M + ++ +S + +N + +S Sbjct: 1574 QIDHLNINTQKLNKEIDRLNLQIQQMNVMQGDLECQNQNLKQQLSLLTSQNQTIQQQSEI 1633 Query: 387 SQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKD 446 + + + D++ +I ++ KLE I+ K Y + + D Sbjct: 1634 NVIEIRSAAYDSEDQI-QDLTQKLEQQIKETEK------YQRAAFNNDQLVQSLQKKISD 1686 Query: 447 TLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLK 506 + +++ Q ++ LI E + + Q+ ++ + ++L+ K+ Sbjct: 1687 ENLQNQKIKQQYEIQIEELIRKINEKEKFDSSTPPKAQIFPQIQNTHLIQENEELLLKID 1746 Query: 507 SAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHH 566 E+ I L +E + K+ + Q ++T+ ++ I + + Sbjct: 1747 QYEKMIRALQEEYYKQQGELQKLTKEYHNVTNQSEQTVVTITQYQQQQDNIKKKEDLTKQ 1806 Query: 567 LSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDL 626 L Q++ +L+++ + D + R+ K E+ N + L ++E + F+L Sbjct: 1807 LQQQIQDLQKKFETERSRYQD-EINRLTT-----KNQELSNQLQNNLNK-QIIE-ENFNL 1858 Query: 627 VQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELA----LVI 682 ++ +L+Q+ K I Q S +E + ++Q + L ++A L+ Sbjct: 1859 KNQIQLLEQELQNTPIKETIIYQSASPLKKNEEEITKYKQQANQLQLRMNQMASDYNLLE 1918 Query: 683 ENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHE 742 + +L+K QL IK L++ ++ ++N+ ++ L +L+++ + +++ ++ E Sbjct: 1919 QQTELEKVQLEKQIKQLQDLEQKLLNENNQQQRQIEALQRQLQQLQMNRQNDMSQELEFE 1978 Query: 743 EQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQL 802 + K+++QF I L + I+ EL + KS+ + + + ++++ L + Sbjct: 1979 LK-KLKSQFEIT------QLQYKQIQEELIQAKSQAFQYRDELVDEQNQKNELNLRIIHY 2031 Query: 803 GSYLQE-KQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQIL--- 858 L E KQ+ E T+ ++ + + V D + KQ+ ++ +N L+K+ Q L Sbjct: 2032 EQILSELKQQNNPESTMIKETTIIKEQV---QDPALIKQVNQLIDDNNSLRKQLQNLEAD 2088 Query: 859 -LEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTL 917 +++ + Q+ + D+ N E+ N +E T T D + ++++ E L Sbjct: 2089 YIQKFRLQQLQIQDLNNKINQNDEE-NYQKTTITEETTINTVSNDQSAEIRKLKDEKLFL 2147 Query: 918 IVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQL-EAQLQEYKNNIENLNM 976 ++E++ + + QIE D + ++Y+ I+ + + E Q + +N ++ M Sbjct: 2148 ----QQELQKQQQLYKKQIEQITNDYEFRIQQYKLTIQQLKESKEIQTNDDQNLLKENQM 2203 Query: 977 NVEELNKMNLEL-IDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNA 1035 E++ + EL I + + Q Q + N++ L + D++I N+ I Sbjct: 2204 LAEQIKHLQNELTISRASFQDQLQQNNQNSTEANKLKSLQKRNEDLDQQIEQQNKIIAQF 2263 Query: 1036 QVSYMSMVSDYESK---LAQFTTKLENMEEEMQR---VSKQLLDSKQHNEELQILVREQD 1089 Q ++ YE K L T +N+ ++ + +S+ S+ HNE+L L D Sbjct: 2264 QQQLQNIQIIYEEKEKELQNLKTNYQNLNSQLNKAPQLSEPENQSRIHNEQLINLQESVD 2323 Query: 1090 D---QIKELKETKLTFEMNIPKTEGMI--ISSTIEPMSDDANNVDXXXXXXXXXXXXLKV 1144 QIK+ +E + I E I + IE + ++ LK Sbjct: 2324 TLNLQIKQYREENNNLKKIIEDQEKEIQDLKLIIENLKHQITQLNLQNDELIQK---LKG 2380 Query: 1145 QEEEEFIQERSVLQEQSAKLNTEL-QECYTKIIQLETLNTE---LTGHDVVNQEQINQLK 1200 QE+ + IQ + Q S+ +L Q+ K +LE +N E L + NQ I +L+ Sbjct: 2381 QEQVQ-IQLKENYQLSSSLDQGKLEQQLINKQFELEQINAENKKLNNKLIDNQNLIRKLQ 2439 Query: 1201 SKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQ 1260 +L E L + +S IS+ +Q +L Q +R+++ + E+ Sbjct: 2440 QELMTYGNEKQKLQ---LQYQSEISALQNQNKSMKQQLLDQQEIKRQSEQIPQKIEINQA 2496 Query: 1261 LSAFES-KYEQLLDSVQSS--TQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQ--EKYAD 1315 S K +Q S+ S + T+ + SL K Q+ + + L+ + AD Sbjct: 2497 HQTVNSPKPKQASKSLNRSDISFHSTDDLRGKYYNCSLYTKNQNGQNYFTPLRAVKSKAD 2556 Query: 1316 VINQIEILRSEIEDE---KVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINE 1372 ++ EI ++ +DE +V+ + + N + KQ++E ++ I+ Sbjct: 2557 LLTTPEISQTNTQDELKKQVSLWQSKYEELLKDKYSKAYMYSPNLN-KQVEETTV-QIDV 2614 Query: 1373 ENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYT-----ITL 1427 N + K N+ + L + + EL +++YQ +Y IT Sbjct: 2615 VNWKSKYEELQEQISNSNIKQGQNEKLIEQLRINN--ELLSTQLYQIQTDYQRIQTEITF 2672 Query: 1428 TQRNDEFENVRQQLVEYEKRIEDLTYE---KESELAILRLKMHENANHYETMQKESEIER 1484 +Q++D + Q + E+ IE L + +E+E+ LR K+ + + ++S ++ Sbjct: 2673 SQKSD----LNQNNLNSERVIEQLNLKIKNQENEIEQLRQKLKQYVESKKNQDQKSNNKQ 2728 Query: 1485 VKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLN-DEITNL 1543 + +++L TE+ +++ L ++ K N ++ ++ +QEI + + D N+ Sbjct: 2729 NEYLKQLE---TENFDYQQEIQSLRIEIKRLQEKNNLIKQSINDQEINLQSGQVDNEVNI 2785 Query: 1544 QNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKEL 1580 + + +Q ++ + QL + KEL Sbjct: 2786 EE-YQQQIEILQNEINIQQNQIYQLQNQLKQSKIKEL 2821 Score = 124 bits (299), Expect = 2e-26 Identities = 262/1320 (19%), Positives = 558/1320 (42%), Gaps = 149/1320 (11%) Query: 306 EKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKK 365 E+ + + + E+ +L + + + ++Q ENKL+ E K Sbjct: 835 EQAQQDNEKLKELYQQNDLNWQKQFQQKYTAALQQLQL-FENKLSLQNKEYNQNIEKQKV 893 Query: 366 GSPLISRKSG--RNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMV-----IQSLN 418 + +K + T K + +QL + D +KK +NE K ++ +Q N Sbjct: 894 NFNQLQQKFNDQKVTIDKQREEINQLKQQN-QDDKNKKPPQNEEIKDDLQKQLNELQKQN 952 Query: 419 KDLVDKEYVISEKDTXXXXXXXXXXGKDTLI---AQLQLEHQQHME-GPSLIHVGTNTED 474 +L+ K + ++KDT + L QLQ + Q++ E I + Sbjct: 953 AELLAK--LKTQKDTQMQYMSKLSQSSENLTNYEKQLQQQTQKYAELNQEYIQF---KQK 1007 Query: 475 VNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHK 534 +++ K Q K + EI K + + + E QL ++++ ++ + + Sbjct: 1008 YDQLQKESTQSKSAQSKEINQYQQK-ITQLQQQMNETSKQLKEKVNQLQSQLLLEQEQCQ 1066 Query: 535 LKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHL-VDYDSGRM 593 + KQ + +F N EI T L Q++ E E++ +Q L + Sbjct: 1067 ILKKQQENFQRDFCMQKTQNGEIQNQTNTLR---QQLIEKEQQLKEVQTILNTKIQVIQQ 1123 Query: 594 IESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSD 653 +E+ V K ++++N A T + SL + Q +L ++L Q + +E+ D+++++ Q Sbjct: 1124 LENQV--KDVQVQN-ASTSKQVQSLNQIQVDNLKKQLQQDQLRINELNDQISNLQQ---- 1176 Query: 654 QVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNY 713 K LE+Q+ A +K+ N+K+ KE + T ++ND + ++L+ Sbjct: 1177 ------KIFTLEQQLQA----EKQ-----NNIKITKE-IQSTKILIQNDYQQQTHQLE-- 1218 Query: 714 IQENMDLTDKLEKMSAEKISELLAKINHEEQS-KIQTQFGIDA--KIQERDLYIENIESE 770 QEN+DL KL+++ + E I ++Q I+ + ++ QE + + N++ + Sbjct: 1219 -QENIDLQQKLKQLEQQLQKERENNIQIQQQFITIENNYQVNQVKSTQENEKIVNNLKFQ 1277 Query: 771 LSKYK-------SRICRLEESIAV-MEDRRYSLERKADQLGSYL--QEKQKAYSEYTI-Q 819 + + K S+I ++ + + M + L L +++QK S I Q Sbjct: 1278 IEQLKLQNEDLSSQIIKVRSNYEIQMSTMNTMTSQNVINLEKQLLFEKEQKENSSMRILQ 1337 Query: 820 EDELVNRLAVLMDHDRVVEK--QLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYN 877 ++ V ++ D+ E QL ++E++N +L K+ ILL Q + + + Sbjct: 1338 LEKQVADFQHIIKSDQTEEYKIQLNQLENQNLKLSKERDILLLSKQRGDEEIKILNVRIS 1397 Query: 878 ALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLE-IEFNTQI 936 L + + +L E + + + Q +E K T QT+I+Q++++ ++ E I ++ Sbjct: 1398 ELSNQNTQNEL-ELMNLRSK-QGNQMEQISKMTTLTQQTVILQQERQSQNNEMILMRQRM 1455 Query: 937 ESAIRDKKV----LNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKH 992 E I+D + L + +++E L +LQ+ N +NL + E + L+ H Sbjct: 1456 EKNIQDHEQQIAELRISFSRDLENQNMLNRKLQDEILNAQNL-LQSERREREFLQKSQSH 1514 Query: 993 VQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQ 1052 ++ Q + ++I KLN+ ++Q EI L N++ + + ++ ++ Sbjct: 1515 SEQVIQQLNQDKQTLHDQILKLNSQIQQLQMEINKLGFNQQNSKDEH----NLFQQQITS 1570 Query: 1053 FTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGM 1112 +TT+++++ Q+++K++ +++ ++ + + Q + LK+ ++++ ++ Sbjct: 1571 YTTQIDHLNINTQKLNKEIDRLNLQIQQMNVMQGDLECQNQNLKQ-----QLSLLTSQ-- 1623 Query: 1113 IISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECY 1172 + TI+ S+ N ++ + E+ IQ+ + EQ K + Q Sbjct: 1624 --NQTIQQQSE-INVIEIRSAAY----------DSEDQIQDLTQKLEQQIKETEKYQRAA 1670 Query: 1173 TKIIQL-ETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQR 1231 QL ++L +++ ++ NQ+ Q + ++E+L + + E + S+ + Sbjct: 1671 FNNDQLVQSLQKKISDENLQNQKIKQQYEIQIEEL-------IRKINE-KEKFDSSTPPK 1722 Query: 1232 GFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETN------- 1284 ++ HL Q + + + A + +Y + +Q T+E N Sbjct: 1723 AQIFPQIQNTHLIQENEELLLKIDQYEKMIRALQEEYYKQQGELQKLTKEYHNVTNQSEQ 1782 Query: 1285 KIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXX 1344 +VT+ Q Q+ ++ KE+ + LQ++ D+ + E RS +DE Sbjct: 1783 TVVTITQYQQQQDNIKKKEDLTKQLQQQIQDLQKKFETERSRYQDE-------------- 1828 Query: 1345 XXXXXXDLRTENQSY-KQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVL 1403 L T+NQ Q+Q I EEN LK + E + Sbjct: 1829 ----INRLTTKNQELSNQLQNNLNKQIIEENFNLKNQIQLLEQELQNTPIK----ETIIY 1880 Query: 1404 ELTHQLELKDSEI---YQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKE-SEL 1459 + L+ + EI Q+ ++ + + Q ++ L+E + +E + EK+ +L Sbjct: 1881 QSASPLKKNEEEITKYKQQANQLQLRMNQMASDY-----NLLEQQTELEKVQLEKQIKQL 1935 Query: 1460 AILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKT 1519 L K+ N N+ + Q E+ ++R ++N + S L ++ +L E + Sbjct: 1936 QDLEQKL-LNENNQQQRQIEA-LQRQLQQLQMNRQNDMSQELEFELKKLKSQFEITQLQY 1993 Query: 1520 NEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKE 1579 ++Q L + + DE+ + QN + +I + S+ KQ + ++TM KE Sbjct: 1994 KQIQEELIQAKSQAFQYRDELVDEQNQKNELNLRIIHYEQILSELKQQNNP--ESTMIKE 2051 Score = 110 bits (265), Expect = 3e-22 Identities = 248/1310 (18%), Positives = 538/1310 (41%), Gaps = 137/1310 (10%) Query: 297 KQSIEPSCEEKTEIEEKGSLEIANMTELTKKIE-LLEHLNCQIRQTNKELENKLATMGTE 355 KQ + + I+++ + + + E ++ L ++ Q KE E Sbjct: 1614 KQQLSLLTSQNQTIQQQSEINVIEIRSAAYDSEDQIQDLTQKLEQQIKETEKYQRAAFNN 1673 Query: 356 SKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDK-KINKNEIAKLEMVI 414 + V S KK IS ++ +N K+K + E + + +K K + + K ++ Sbjct: 1674 DQLVQSLQKK----ISDENLQN--QKIKQQYEIQIEELIRKINEKEKFDSSTPPKAQIFP 1727 Query: 415 QSLNKDLVDKE----YVISEKDTXXXXXXXXXXGKDTLIAQLQLE-HQQHMEGPSLIHVG 469 Q N L+ + I + + + + +L E H + + Sbjct: 1728 QIQNTHLIQENEELLLKIDQYEKMIRALQEEYYKQQGELQKLTKEYHNVTNQSEQTVVTI 1787 Query: 470 TNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEE--QITQLNDEI-----DAA 522 T + + K +E L ++L +I+D+ K E+ + +E ++T N E+ + Sbjct: 1788 TQYQQQQDNIKKKEDLTKQLQQQIQDLQKKFETERSRYQDEINRLTTKNQELSNQLQNNL 1847 Query: 523 NKNMIKVKSNHKLKLKQMQKTIDNF-----------SKVSDSNKEIVRLTEELHHLSQKV 571 NK +I+ N K +++ +++ + N S + + +EI + ++ + L ++ Sbjct: 1848 NKQIIEENFNLKNQIQLLEQELQNTPIKETIIYQSASPLKKNEEEITKYKQQANQLQLRM 1907 Query: 572 AELEEEKGNL--QLHLVDYDSGRMIES--DVYKKMIEMENLAETRLKAIS-----LLESQ 622 ++ + L Q L + I+ D+ +K++ N + +++A+ L ++ Sbjct: 1908 NQMASDYNLLEQQTELEKVQLEKQIKQLQDLEQKLLNENNQQQRQIEALQRQLQQLQMNR 1967 Query: 623 KFDLVQELHI-LQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALV 681 + D+ QEL L++ + E Q+Q + + ++ ++ +++ K EL L Sbjct: 1968 QNDMSQELEFELKKLKSQFEITQLQYKQIQEELIQAKSQAFQYRDELVDEQNQKNELNLR 2027 Query: 682 IENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSA--EKISELLAKI 739 I + EQ+ +K +N+ E M K I+E + +++++ + + L ++ Sbjct: 2028 I----IHYEQILSELKQ-QNNPESTMIKETTIIKEQVQDPALIKQVNQLIDDNNSLRKQL 2082 Query: 740 NHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESI-AVMEDRRYSLERK 798 + E IQ +F + ++Q +DL + +++ Y+ E +I V D+ + + Sbjct: 2083 QNLEADYIQ-KFRLQ-QLQIQDLNNKINQNDEENYQKTTITEETTINTVSNDQSAEIRKL 2140 Query: 799 ADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKN-QI 857 D+ QE QK Y Q +++ N + ++ +QL E+KE+Q + Q Sbjct: 2141 KDEKLFLQQELQKQQQLYKKQIEQITNDYEFRIQQYKLTIQQL----KESKEIQTNDDQN 2196 Query: 858 LLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTL 917 LL+ENQ L + +Q + +A+ +Q QL + N + T ++ Sbjct: 2197 LLKENQMLAEQIKHLQNELT--ISRAS-----------FQDQL---QQNNQNSTEANKLK 2240 Query: 918 IVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYV-TQLEAQLQEYKNNIENLNM 976 +QK+ E D +IE +I + + + +NI+ + + E +LQ K N +NLN Sbjct: 2241 SLQKRNEDLDQQIEQQNKIIAQFQQQL-------QNIQIIYEEKEKELQNLKTNYQNLN- 2292 Query: 977 NVEELNKMNLELIDKHVQKQQTQSPDYTEQYIN---EINKLNALLKQKDEEIIALNQKIN 1033 +LNK + + + QS + EQ IN ++ LN +KQ EE N Sbjct: 2293 --SQLNKA------PQLSEPENQSRIHNEQLINLQESVDTLNLQIKQYREE--------N 2336 Query: 1034 NAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQ---LLDSKQHNEELQILVREQDD 1090 N + ++ D E ++ +EN++ ++ +++ Q L+ + E++QI ++E Sbjct: 2337 N---NLKKIIEDQEKEIQDLKLIIENLKHQITQLNLQNDELIQKLKGQEQVQIQLKENYQ 2393 Query: 1091 QIKELKETKLTFEMNIPKTEGMIISSTIEPMSD---DANNVDXXXXXXXXXXXXLKVQEE 1147 L + KL ++ + E I++ + +++ D N+ K + + Sbjct: 2394 LSSSLDQGKLEQQLINKQFELEQINAENKKLNNKLIDNQNLIRKLQQELMTYGNEKQKLQ 2453 Query: 1148 EEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELT---GHDVVNQEQINQLKSKLE 1204 ++ E S LQ Q+ + +L + Q E + ++ H VN + Q L Sbjct: 2454 LQYQSEISALQNQNKSMKQQLLDQQEIKRQSEQIPQKIEINQAHQTVNSPKPKQASKSLN 2513 Query: 1205 QLNTE---NDNLLSTVAELRSSISSAVDQRGFEIAELWKQH---LAQREADFQKTEHELR 1258 + + D+L + Q F K L E T+ EL+ Sbjct: 2514 RSDISFHSTDDLRGKYYNCSLYTKNQNGQNYFTPLRAVKSKADLLTTPEISQTNTQDELK 2573 Query: 1259 VQLSAFESKYEQLLDSVQS-------STQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQE 1311 Q+S ++SKYE+LL S + ++ + V + ++K ++ +E + N Sbjct: 2574 KQVSLWQSKYEELLKDKYSKAYMYSPNLNKQVEETTVQIDVVNWKSKYEELQEQISNSNI 2633 Query: 1312 KYADVINQIEILR--SEIEDEKV--AFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSI 1367 K IE LR +E+ ++ DL N + +++ EQ Sbjct: 2634 KQGQNEKLIEQLRINNELLSTQLYQIQTDYQRIQTEITFSQKSDLNQNNLNSERVIEQLN 2693 Query: 1368 LNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITL 1427 L I + ++++ + + K E QLE ++ + Q+ I + Sbjct: 2694 LKIKNQENEIEQLRQKLKQYVESKKNQDQKSNNKQNEYLKQLETENFDYQQEIQSLRIEI 2753 Query: 1428 TQRNDEFENVRQQLVEYEKRIE------DLTYEK-ESELAILRLKMHENANHYETMQKES 1480 + ++ ++Q + + E ++ ++ E+ + ++ IL+ +++ N +Q + Sbjct: 2754 KRLQEKNNLIKQSINDQEINLQSGQVDNEVNIEEYQQQIEILQNEINIQQNQIYQLQNQL 2813 Query: 1481 EIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQE 1530 + ++K + EL K+ +V + EL + +++ + Q + Q+ Sbjct: 2814 KQSKIKEL-ELEQKLKYAVEDLEHAQELQQQQQQQQQYQQKQQQQQQQQQ 2862 Score = 105 bits (252), Expect = 1e-20 Identities = 234/1367 (17%), Positives = 552/1367 (40%), Gaps = 106/1367 (7%) Query: 174 DLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWK 233 DL +++ + QI + + K T E + Q + + I K Sbjct: 1802 DLTKQLQQ--QIQDLQKKFETERSRYQDEINRLTTKNQELSNQLQNNLNKQIIEENFNLK 1859 Query: 234 DEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXX 293 ++ Q L +++++ ++ + + ++ L+ EI+ K Q+ Q Sbjct: 1860 NQIQLLEQELQNTPIKETIIYQSASPLKKNEEEIT----KYKQQANQLQLRMNQMASDYN 1915 Query: 294 XLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMG 353 L +Q+ + + +I++ LE + E ++ +E L Q++Q +N ++ Sbjct: 1916 LLEQQTELEKVQLEKQIKQLQDLEQKLLNENNQQQRQIEALQRQLQQLQMNRQNDMS-QE 1974 Query: 354 TESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMV 413 E + S+ + K + + KS Q E +++ K I E + Sbjct: 1975 LEFELKKLKSQFEITQLQYKQIQEELIQAKSQAFQYRDELVDEQNQKNELNLRIIHYEQI 2034 Query: 414 IQSLNKD------LVDKEYVISEK---DTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPS 464 + L + ++ + +I E+ ++L QLQ +++ Sbjct: 2035 LSELKQQNNPESTMIKETTIIKEQVQDPALIKQVNQLIDDNNSLRKQLQNLEADYIQKFR 2094 Query: 465 L-------IHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQ-LN 516 L ++ N D K + +N D + + I KLK + + Q L Sbjct: 2095 LQQLQIQDLNNKINQNDEENYQKTTITEETTINTVSNDQSAE--IRKLKDEKLFLQQELQ 2152 Query: 517 DEIDAANKNMIKVKSNHKLKLKQMQKTIDNF--SKVSDSN------KEIVRLTEELHHLS 568 + K + ++ ++++ +++Q + TI SK +N KE L E++ HL Sbjct: 2153 KQQQLYKKQIEQITNDYEFRIQQYKLTIQQLKESKEIQTNDDQNLLKENQMLAEQIKHLQ 2212 Query: 569 QKVAELEEE-KGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLV 627 ++ + LQ + + ++S + K+ +++ E + K I+ + Q ++ Sbjct: 2213 NELTISRASFQDQLQQNNQNSTEANKLKS-LQKRNEDLDQQIEQQNKIIAQFQQQLQNIQ 2271 Query: 628 -------QELHILQQKYDEVEDKLADISQLQSDQVCSEIKS---VHLEEQIDALSASKKE 677 +EL L+ Y + +L QL + S I + ++L+E +D L+ K+ Sbjct: 2272 IIYEEKEKELQNLKTNYQNLNSQLNKAPQLSEPENQSRIHNEQLINLQESVDTLNLQIKQ 2331 Query: 678 LALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLA 737 NLK E I+DL+ E++ +++ Q N+ + ++K+ ++ ++ Sbjct: 2332 YREENNNLKKIIEDQEKEIQDLKLIIENLKHQIT---QLNLQNDELIQKLKGQEQVQIQL 2388 Query: 738 KINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDR--RYSL 795 K N++ S + Q ++ ++ + +E I +E K +++ + I ++ Y Sbjct: 2389 KENYQLSSSLD-QGKLEQQLINKQFELEQINAENKKLNNKLIDNQNLIRKLQQELMTYGN 2447 Query: 796 ERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKN 855 E++ QL Y E ++ + +L+++ + +++ +K + H+ K Sbjct: 2448 EKQKLQL-QYQSEISALQNQNKSMKQQLLDQQEIKRQSEQIPQKIEINQAHQTVNSPKPK 2506 Query: 856 QILLEENQN-LQI-SLSDMQ-QHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITH 912 Q N++ + S D++ ++YN + N+ Y T LR ++S +T Sbjct: 2507 QASKSLNRSDISFHSTDDLRGKYYNCSLYTKNQN------GQNYFTPLRAVKSKADLLT- 2559 Query: 913 EHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIE 972 T + + ++L+ + + + +++L +KY K Y L Q++E I+ Sbjct: 2560 ---TPEISQTNTQDELKKQVSLWQS---KYEELLKDKYSKAYMYSPNLNKQVEETTVQID 2613 Query: 973 NLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKI 1032 +N + ++ ++ + ++++ Q + + NE+ L+ L Q + + +I Sbjct: 2614 VVNWK-SKYEELQEQISNSNIKQGQNEKLIEQLRINNEL--LSTQLYQIQTDYQRIQTEI 2670 Query: 1033 NNAQVSYMSMVS-DYESKLAQFTTKLENMEEEMQRVS---KQLLDSKQHNEELQILVREQ 1088 +Q S ++ + + E + Q K++N E E++++ KQ ++SK++ ++ +Q Sbjct: 2671 TFSQKSDLNQNNLNSERVIEQLNLKIKNQENEIEQLRQKLKQYVESKKNQDQKSN--NKQ 2728 Query: 1089 DDQIKELKETKLTFEMNIP----KTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKV 1144 ++ +K+L+ ++ I + + + + + S + ++ + Sbjct: 2729 NEYLKQLETENFDYQQEIQSLRIEIKRLQEKNNLIKQSINDQEINLQSGQVDNEVNIEEY 2788 Query: 1145 QEEEEFIQ-ERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKL 1203 Q++ E +Q E ++ Q Q +L +L++ K ++LE + D+ + +++ Q + + Sbjct: 2789 QQQIEILQNEINIQQNQIYQLQNQLKQSKIKELELEQ-KLKYAVEDLEHAQELQQQQQQQ 2847 Query: 1204 EQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSA 1263 +Q + + + Q+ + ++Q+ F ++ +LS Sbjct: 2848 QQYQQKQQQQQQQQQQQQQQQQQPQQQQTQIVQTQYEQN-----NQFDDQYRQILYELSL 2902 Query: 1264 FESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYAD---VINQI 1320 +S+ L +Q ST+ + + ++++ +L L N Q+K D +N++ Sbjct: 2903 IKSQNSSLQTQLQESTKTQVRLMQEIKELQIQNERLNISNVRLHNEQQKTTDQDNQVNRV 2962 Query: 1321 EILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSY-----KQMQEQSILNINEENA 1375 L E++ E ++ Q Y ++++Q I ++ E A Sbjct: 2963 NDLYKEVQIENQKLRSEISYLQQEKQQLISSFESKLQQYSASANSKIRQQQIEDLKRELA 3022 Query: 1376 QLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLE---LKDSEIYQKTHEYTITLTQRND 1432 QLK+++ + + +L QLE +K+ E+ QK + +Q Sbjct: 3023 QLKRATLKSSGVDIEAERLTYSTQ--ITQLKKQLEYEQIKNKELLQKLQ----SSSQYQS 3076 Query: 1433 EFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKE 1479 +F V + E + +I +L K +++ E M+KE Sbjct: 3077 DFGLVERLNKELQDKIVELHQVKSEYKNAIQMIHSLEEQVIERMEKE 3123 Score = 100 bits (240), Expect = 3e-19 Identities = 227/1124 (20%), Positives = 462/1124 (41%), Gaps = 142/1124 (12%) Query: 455 EHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQ 514 E Q+ + P I N + + QEQ KQE + N KD ++ ++ E Q Sbjct: 697 EQQKEQQTPEQISKPQNPAE--QTKPKQEQPKQEEPQK----NPKDQVKNPQNPENLQKQ 750 Query: 515 LNDEIDAA-NKNMI-KVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVA 572 + N +++ KV N + + KQ K ++N K++V+ E L Sbjct: 751 PQKPQNVPQNPSVVNKVSQNPQFQNKQ-PKNLENL-------KQLVQQPESLRRSQPTSV 802 Query: 573 ELEEEKGNLQLHLVDYDSGRMI--ESDVYKKMIEMENLAETRLKAISLLESQKFDLVQEL 630 ++K + L D + R E D K ++E +LK + Q+ DL + Sbjct: 803 RNSQDKKQIAL-AQDAEELRKQKQELDRLKNLLEQAQQDNEKLKELY----QQNDLNWQK 857 Query: 631 HILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKE 690 QQKY A + QLQ + +++ + I+ + +L + K+ + Sbjct: 858 QF-QQKYT------AALQQLQLFENKLSLQNKEYNQNIEKQKVNFNQLQQKFNDQKVTID 910 Query: 691 QLYGTIKDLENDKEDIMNKLQNYIQE-NMDLTDKLEKMSAEKISELLAKINHEEQSKIQT 749 + I L+ +D NK +E DL +L ++ + +ELLAK+ ++ +++Q Sbjct: 911 KQREEINQLKQQNQDDKNKKPPQNEEIKDDLQKQLNELQKQN-AELLAKLKTQKDTQMQY 969 Query: 750 QFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEK 809 +K+ + + N E +L + + L + ++K DQL + Sbjct: 970 M----SKLSQSSENLTNYEKQLQQQTQKYAELNQEY-------IQFKQKYDQLQKESTQS 1018 Query: 810 QKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISL 869 + A S+ Q + + +L M+ KQL E K Q ++Q+LLE+ Q QI L Sbjct: 1019 KSAQSKEINQYQQKITQLQQQMNE---TSKQLKE-----KVNQLQSQLLLEQEQ-CQI-L 1068 Query: 870 SDMQQHY--NALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIED 927 Q+++ + ++K ++ +T Q QL + E LK + QT++ K + I+ Sbjct: 1069 KKQQENFQRDFCMQKTQNGEIQNQTNTLRQ-QLIEKEQQLKEV----QTILNTKIQVIQ- 1122 Query: 928 LEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLE 987 Q+E+ ++D +V N K ++ + Q+ Q+ K ++ + + ELN Sbjct: 1123 -------QLENQVKDVQVQNASTSKQVQSLNQI--QVDNLKKQLQQDQLRINELN----- 1168 Query: 988 LIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYE 1047 D+ QQ +I L L+ + + I + ++I + ++ + +DY+ Sbjct: 1169 --DQISNLQQ------------KIFTLEQQLQAEKQNNIKITKEIQSTKI---LIQNDYQ 1211 Query: 1048 SKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEEL--QILVREQDDQIKELKETKLTFEMN 1105 + Q + +++++++++ +QL +++N ++ Q + E + Q+ ++K T+ E Sbjct: 1212 QQTHQLEQENIDLQQKLKQLEQQLQKERENNIQIQQQFITIENNYQVNQVKSTQEN-EKI 1270 Query: 1106 IPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQ-ERSVLQEQSAKL 1164 + + I ++ D ++ + + + I E+ +L E+ K Sbjct: 1271 VNNLKFQIEQLKLQ-NEDLSSQIIKVRSNYEIQMSTMNTMTSQNVINLEKQLLFEKEQKE 1329 Query: 1165 NTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNL-LSTVAELRSS 1223 N+ + +I+QLE + ++ +Q + K +L QL EN NL LS ++ Sbjct: 1330 NSSM-----RILQLEKQVADF--QHIIKSDQTEEYKIQLNQL--ENQNLKLSKERDILLL 1380 Query: 1224 ISSAVDQR----GFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDS---VQ 1276 D+ I+EL Q+ Q E + + Q+ SK L +Q Sbjct: 1381 SKQRGDEEIKILNVRISELSNQN-TQNELELMNLRSKQGNQMEQI-SKMTTLTQQTVILQ 1438 Query: 1277 SSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXX 1336 Q + N+++ M Q ++ +QD E+ + L+ ++ + +L +++DE Sbjct: 1439 QERQSQNNEMILMRQ--RMEKNIQDHEQQIAELRISFSRDLENQNMLNRKLQDE-----I 1491 Query: 1337 XXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVN 1396 + ++QS+ EQ I +N++ L +N Sbjct: 1492 LNAQNLLQSERREREFLQKSQSH---SEQVIQQLNQDKQTLHDQILKLNSQIQQLQMEIN 1548 Query: 1397 DAEAKVLELTHQLELKDSEIYQKTHE---YTITLTQRNDEFENVRQQLVEYEKRIEDLTY 1453 + L +I T + I + N E + + Q+ + DL Sbjct: 1549 KLGFNQQNSKDEHNLFQQQITSYTTQIDHLNINTQKLNKEIDRLNLQIQQMNVMQGDLEC 1608 Query: 1454 EKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALE 1513 + ++ L L +N +T+Q++SEI +++ + + Q+ +L + LE Sbjct: 1609 QNQNLKQQLSLLTSQN----QTIQQQSEINVIEI-------RSAAYDSEDQIQDLTQKLE 1657 Query: 1514 EEVAKTNEMQTALENQEIEIVTLNDEIT--NLQNMVRASSSKIQ 1555 +++ +T + Q A N + + +L +I+ NLQN +IQ Sbjct: 1658 QQIKETEKYQRAAFNNDQLVQSLQKKISDENLQNQKIKQQYEIQ 1701 Score = 74.1 bits (174), Expect = 3e-11 Identities = 167/907 (18%), Positives = 381/907 (42%), Gaps = 76/907 (8%) Query: 240 LKDIESKDVRISS-LEEANKLLEAARFEISLEHSKLAQELE----QXXXXXXXXXXXXXX 294 LK ++ ++ + +E+ NK++ A+F+ L++ ++ E + Q Sbjct: 2239 LKSLQKRNEDLDQQIEQQNKII--AQFQQQLQNIQIIYEEKEKELQNLKTNYQNLNSQLN 2296 Query: 295 LAKQSIEPSCEEKTEIEEKGSL-EIANMTELTKKIELLEHLNCQ--IRQTNKELENKLAT 351 A Q EP + + E+ +L E + L K E+ N + I KE+++ Sbjct: 2297 KAPQLSEPENQSRIHNEQLINLQESVDTLNLQIKQYREENNNLKKIIEDQEKEIQDLKLI 2356 Query: 352 MGTESKAVSSPSKKGSPLISRKSGRNTAS-KMKSPWSQLSSETLNQDTDKKINKN-EIAK 409 + ++ + + LI + G+ ++K + SS + + INK E+ + Sbjct: 2357 IENLKHQITQLNLQNDELIQKLKGQEQVQIQLKENYQLSSSLDQGKLEQQLINKQFELEQ 2416 Query: 410 LEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVG 469 + + LN L+D + +I + G + +LQL++Q + + Sbjct: 2417 INAENKKLNNKLIDNQNLIRKLQQELMTY-----GNEK--QKLQLQYQSEISALQNQNKS 2469 Query: 470 TNTE--DVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMI 527 + D EI + EQ+ Q++ EI + K K A + + + +I + + + Sbjct: 2470 MKQQLLDQQEIKRQSEQIPQKI--EINQAHQTVNSPKPKQASKSLNR--SDISFHSTDDL 2525 Query: 528 KVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVD 587 + K + + Q + F+ + + LT + EL+++ Q + Sbjct: 2526 RGKYYNCSLYTKNQNGQNYFTPLRAVKSKADLLTTPEISQTNTQDELKKQVSLWQSKYEE 2585 Query: 588 YDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQEL----HILQQKYDEVEDK 643 + ++ +Y + + + ET ++ + K++ +QE +I Q + +++ ++ Sbjct: 2586 LLKDKYSKAYMYSPNLNKQ-VEETTVQIDVVNWKSKYEELQEQISNSNIKQGQNEKLIEQ 2644 Query: 644 LADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDK 703 L ++L S Q+ +I++ + Q + + K +L N + EQL IK+ EN+ Sbjct: 2645 LRINNELLSTQLY-QIQTDYQRIQTEITFSQKSDLNQNNLNSERVIEQLNLKIKNQENEI 2703 Query: 704 EDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLY 763 E + KL+ Y++ + K E + +L + N + Q +IQ+ ++QE++ Sbjct: 2704 EQLRQKLKQYVESKKNQDQKSNNKQNEYLKQLETE-NFDYQQEIQSLRIEIKRLQEKNNL 2762 Query: 764 IE--------NIES-------ELSKYKSRICRLEESIAVMEDRRYSLERKADQLG-SYLQ 807 I+ N++S + +Y+ +I L+ I + +++ Y L+ + Q L+ Sbjct: 2763 IKQSINDQEINLQSGQVDNEVNIEEYQQQIEILQNEINIQQNQIYQLQNQLKQSKIKELE 2822 Query: 808 EKQKAYSEYTIQEDELVNRL-AVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQ 866 +QK +Y +++ E L + +KQ + + + ++ Q++ Q ++ Q +Q Sbjct: 2823 LEQKL--KYAVEDLEHAQELQQQQQQQQQYQQKQQQQQQQQQQQQQQQQQPQQQQTQIVQ 2880 Query: 867 ISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKK-EI 925 Q + + L +S+++ QTQL++ R+ E + L +Q ++ I Sbjct: 2881 TQYEQNNQFDDQYRQILYELSLIKSQNSSLQTQLQESTKTQVRLMQEIKELQIQNERLNI 2940 Query: 926 EDLEIEFNTQ-----------IESAIRDKKVLNEKYEKNIEYVTQ--------LEAQLQE 966 ++ + Q + ++ ++ N+K I Y+ Q E++LQ+ Sbjct: 2941 SNVRLHNEQQKTTDQDNQVNRVNDLYKEVQIENQKLRSEISYLQQEKQQLISSFESKLQQ 3000 Query: 967 YKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEII 1026 Y + N + +++ + EL ++ D + + ++ L KQ + E I Sbjct: 3001 YSAS-ANSKIRQQQIEDLKRELAQLKRATLKSSGVDIEAERLTYSTQITQLKKQLEYEQI 3059 Query: 1027 ALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQ--HNEELQIL 1084 + + Q S SD+ + + +L++ E+ +V + ++ Q H+ E Q++ Sbjct: 3060 KNKELLQKLQ-SSSQYQSDF-GLVERLNKELQDKIVELHQVKSEYKNAIQMIHSLEEQVI 3117 Query: 1085 VREQDDQ 1091 R + +Q Sbjct: 3118 ERMEKEQ 3124 Score = 46.8 bits (106), Expect = 0.005 Identities = 43/169 (25%), Positives = 86/169 (50%), Gaps = 13/169 (7%) Query: 914 HQTLIVQK---KKEIEDL-EIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKN 969 H+ L+ +K +K+++DL + Q I+DK E+ K + +T+L Q+ + KN Sbjct: 9 HKILLSKKDYYEKKMQDLIDRGIPNQYLLEIQDK----EQIAKQAQTITELNQQILQ-KN 63 Query: 970 NIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALN 1029 + + + +MNL LI + + Q + E YI E+ K N +LKQ+ E+ +L Sbjct: 64 ALITQILQEKSQQEMNL-LISQQLFVINEQYKN-AEIYIQELQKENQILKQQFEDAPSLR 121 Query: 1030 QKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVS--KQLLDSKQ 1076 QK+ N + Y ++ + ++ T+ ++ + +++ QLL+ K+ Sbjct: 122 QKLYNLEQWYAKLIHEKNQEIQLLKTQQPHIVQHAPQLNIINQLLEQKE 170 >UniRef50_UPI00006CC010 Cluster: hypothetical protein TTHERM_00411580; n=1; Tetrahymena thermophila SB210|Rep: hypothetical protein TTHERM_00411580 - Tetrahymena thermophila SB210 Length = 3554 Score = 142 bits (345), Expect = 5e-32 Identities = 216/1109 (19%), Positives = 484/1109 (43%), Gaps = 107/1109 (9%) Query: 467 HVGTNT--EDVNEIAKVQEQLKQELNDEIK-DVNVKDLIEKLKSAE-EQITQLNDEIDAA 522 ++G+N E + KV+ KQ+ N +++ D N + K+ E ++ Q D+I+ Sbjct: 2393 NLGSNQSIESTEDTEKVKRNKKQKQNKQVELDNNSNTVRSNSKNEEIQKYIQQQDQINNL 2452 Query: 523 NKNMIKVK------SNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHL--SQKVAEL 574 K +++++ +++++K++ + I+ + ++ ++L ++ + + + Sbjct: 2453 EKQILQLQIYESQDQQNQIRIKELNEKINQLQLQNLELEDKIKLKSKVDTMLSANQNQNQ 2512 Query: 575 EEEKGNLQLHLVDYDSGRMIESDVYKK--MIEMENLAETRLKAISLLESQKFDLVQ-ELH 631 E+EK + L + + ++I S K+ +IE +L +++LK + L+ Q +LV+ + + Sbjct: 2513 EDEKKMIDLLVQIEELNKIINSQNSKEQQLIEENSLLKSQLKTLQDLQIQNEELVKFQKN 2572 Query: 632 ILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQ 691 +++K +ED+L D+ Q+ ++ S+ K+ E++I + K+ + L K Q Sbjct: 2573 YIKEK-QIIEDRLKDLDQV-IEKNNSQYKNKIEEQRITIKNLEKR--------IDLFKSQ 2622 Query: 692 LYGTIKDLENDKED---IMNKLQNYIQENMDLTDKLEKMSAE----KISELLAKINHEEQ 744 IKD N ++D I N Y Q+ L ++LE + + ++ K+ E+Q Sbjct: 2623 SVNNIKDKTNFEQDFYSIQNINAEYSQQVQKLKNELEVLQVKYKQLQVDNSQLKVQSEQQ 2682 Query: 745 SKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGS 804 +K+ +Q +++ ++ +L++ S++ LE I E+++D + Sbjct: 2683 NKVYSQ-------NKKEF--GELQFQLNQANSKVLLLENQIKQKIVADNDNEKQSDTIKG 2733 Query: 805 ---YLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEE 861 + E K +E+ Q+ +L + + + +++ ++ ++ K + +K Q L E Sbjct: 2734 NDYFSSELIKLQAEFKNQD----KKLEIEKNQNLILQNNIINLQ---KIINQKQQELKNE 2786 Query: 862 NQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQK 921 + + ++Q+ N L+++ SE T+ L+ L++N + T + +++ Sbjct: 2787 KEESNTKFNLLEQNVNGLIQQNQSLKQQISEKTQ---SLQVLQNNYDQATKK-----LKE 2838 Query: 922 KKEIEDLEIEFNTQIESAIRDKKVLN-------EKYEKNIEYVTQLEAQLQEYKNNIENL 974 K ++++L + Q+ I+D L E++ K ++ LE+Q+ YK I L Sbjct: 2839 KMQVQELYEKQQNQLNQLIQDSACLQQELSRSKEEFNKKVQEQIDLESQIFNYKEQIFKL 2898 Query: 975 NMNVEEL-NKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNAL---LKQKDEEIIALNQ 1030 + +++ + +N++ I Q Q+ ++ +N+I ++N+ LKQ + +I N Sbjct: 2899 ELQLKKYQSNLNVDNISSASNTLQDQNDQRSQDLLNQIQRINSQNMQLKQSLDLVIEQNN 2958 Query: 1031 KINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDD 1090 K+ + + + ++ ++ Q+ + +E+E +K+ H+ L++ +RE +D Sbjct: 2959 KLADEVLLQKNQMNSMNQQILQYQQTISQLEDEQNEKTKKSKKIDMHSNNLELQIRELED 3018 Query: 1091 QIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEF 1150 QI+ + L + + I SS + +S N VD KV++ E+ Sbjct: 3019 QIR--SKDLLVNSIQLELDNYRITSS--QKLSSIQNQVDEKTK---------KVEKLEQI 3065 Query: 1151 IQE-RSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTE 1209 QE Q+ +L+ + Q IQ+ L E VVN +N ++ + LNT+ Sbjct: 3066 YQESEKNFQKHLVELSKKDQAIKNLQIQMSAL--ESKNLHVVN--DLNLIQQREATLNTQ 3121 Query: 1210 NDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYE 1269 L+ ++LR+ D ++ L K++ +E K + F + + Sbjct: 3122 VKQLVQENSQLRAQ-KIISDASQMNLSALIKENQILKEQHLTKIALIKYQVKNLFNHELK 3180 Query: 1270 QLLDSV-QSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYA-------DVINQIE 1321 Q ++ V Q S Q+E T++ LQ +LQ+++ +LQ Y + IN E Sbjct: 3181 QSIEKVKQISLQKEQQLHATIQ---ILQQQLQEEKSKYESLQTTYTSRNKKSQEHINADE 3237 Query: 1322 ILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSS 1381 + +++I + +N S K+ E+ + I + L S Sbjct: 3238 LKQNQIIISNKYQSTDLILDPQQIFSTLSQVVNDNTSLKKFIEEMSVKILQMQETLHNSL 3297 Query: 1382 XXXXXXXXXXXXRVNDAEAKVLELT---HQLELKDSEIYQKTHEYTITLTQRNDEFENVR 1438 D + + + HQ+E + +I Q ++ + ++N N+ Sbjct: 3298 ELLWKEQNVFMSCNLDTQEEQTNSSIQHHQIEKQVKQIIQNLNQLKMHKDEQNVSSGNLN 3357 Query: 1439 QQ---LVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKI 1495 Q + + + E + LK Y + E+ +++++ +E+ N K+ Sbjct: 3358 YQDSSSLPISLQAINKQQEDDGNNQSCLLKQITQFTQYTQQELENVVQQIEFLEKQN-KL 3416 Query: 1496 TESVSLNKQVAELNKALEEEVAKTNEMQT 1524 ++ N Q +E +V K + T Sbjct: 3417 LKNQLQNTQKENNKLLIELKVVKEQYINT 3445 Score = 120 bits (288), Expect = 4e-25 Identities = 225/1116 (20%), Positives = 484/1116 (43%), Gaps = 102/1116 (9%) Query: 473 EDVNEIAKV---QEQLKQELNDEIKDVNVKDLI-EKLKSAEEQITQLNDEIDAANKNMIK 528 +D N KV +EQ ++EL I+D L+ ++ + +QIT+L+D++ ++++IK Sbjct: 2143 KDENSSLKVKLQEEQQQKELLRNIQDNKQVPLLKQQAQQMIDQITKLSDQLKVKDQDLIK 2202 Query: 529 VKSN-HKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVD 587 K+N +++ Q + I K+ +S L + K A+ E EK N+ + + Sbjct: 2203 AKNNLLEIQYSQQNENIQLKQKLQESEL-------NLQYWKTKCADTEAEK-NMWISQYN 2254 Query: 588 YDSGRMIESD--VYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKL- 644 I D + IE++N + LK ++ QK + V L IL ++E+K+ Sbjct: 2255 QSVLNQIAQDKKIQDSKIEIDNQHKEYLKV--QIDEQKKE-VDSLKILNSNL-QLENKIL 2310 Query: 645 -ADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVI--ENL-KLDKEQLYGTIKDLE 700 I+QL+ + KS ++ + +L ++L ++ EN KL K + + +LE Sbjct: 2311 SEQINQLKESVTSFQYKSQFKDQYLGSLIRDLEQLNQIVRQENQEKLSKSNIEEQL-NLE 2369 Query: 701 NDKEDIMNKLQNYIQENMDLT-DKLEKMSAEKISELLAKINHEEQSKIQTQFGID----- 754 + +I+ K ++ + T + L + + +E K+ ++ K Q +D Sbjct: 2370 QGRNEILRKHCQELELKIKTTQNNLGSNQSIESTEDTEKVKRNKKQKQNKQVELDNNSNT 2429 Query: 755 ----AKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLE-RKADQLGSYLQEK 809 +K +E YI+ + +++ + +I +L+ I +D++ + ++ ++ + LQ + Sbjct: 2430 VRSNSKNEEIQKYIQQ-QDQINNLEKQILQLQ--IYESQDQQNQIRIKELNEKINQLQLQ 2486 Query: 810 QKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQK-------KNQILLEEN 862 + + ++ L+ + ++ EK+++++ + +EL K K Q L+EEN Sbjct: 2487 NLELEDKIKLKSKVDTMLSANQNQNQEDEKKMIDLLVQIEELNKIINSQNSKEQQLIEEN 2546 Query: 863 QNLQISLSDMQ--QHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQ 920 L+ L +Q Q N + K + + E + + +L+DL+ +++ +++ I + Sbjct: 2547 SLLKSQLKTLQDLQIQNEELVKFQKNYIKEKQI--IEDRLKDLDQVIEKNNSQYKNKIEE 2604 Query: 921 KKKEIEDLEIE---FNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMN 977 ++ I++LE F +Q + I+DK + + + Q+Q+ KN +E L + Sbjct: 2605 QRITIKNLEKRIDLFKSQSVNNIKDKTNFEQDFYSIQNINAEYSQQVQKLKNELEVLQVK 2664 Query: 978 VEELNKMNLELIDKHVQKQQTQSPDYTE----QY-INEIN-KLNALLKQKDEEIIALNQK 1031 ++L N +L + Q+ + S + E Q+ +N+ N K+ L Q ++I+A N Sbjct: 2665 YKQLQVDNSQLKVQSEQQNKVYSQNKKEFGELQFQLNQANSKVLLLENQIKQKIVADND- 2723 Query: 1032 INNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQ 1091 N Q + + S+L + + +N +++++ Q L + + LQ ++ ++ + Sbjct: 2724 -NEKQSDTIKGNDYFSSELIKLQAEFKNQDKKLEIEKNQNLILQNNIINLQKIINQKQQE 2782 Query: 1092 IK-ELKETKLTFEMNIPKTEGMI--ISSTIEPMSDDANNVDXXXXXXXXXXXXL--KVQE 1146 +K E +E+ F + G+I S + +S+ ++ L K+Q Sbjct: 2783 LKNEKEESNTKFNLLEQNVNGLIQQNQSLKQQISEKTQSLQVLQNNYDQATKKLKEKMQV 2842 Query: 1147 EEEFIQERSVLQ---EQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKL 1203 +E + ++++ L + SA L EL + + +L +EQI +L+ +L Sbjct: 2843 QELYEKQQNQLNQLIQDSACLQQELSRSKEEFNKKVQEQIDLESQIFNYKEQIFKLELQL 2902 Query: 1204 E--QLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREA------DFQKTEH 1255 + Q N DN+ S L+ +I + Q++ +++ K Sbjct: 2903 KKYQSNLNVDNISSASNTLQDQNDQRSQDLLNQIQRINSQNMQLKQSLDLVIEQNNKLAD 2962 Query: 1256 ELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYAD 1315 E+ +Q + S +Q+L Q+ +Q E + ++ + + E +R L+ D Sbjct: 2963 EVLLQKNQMNSMNQQILQYQQTISQLEDEQNEKTKKSKKIDMHSNNLELQIRELE----D 3018 Query: 1316 VINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENA 1375 I ++L + I+ E + + + + +Q+ ++S N + Sbjct: 3019 QIRSKDLLVNSIQLELDNYRITSSQKLSSIQNQVDEKTKKVEKLEQIYQESEKNFQKHLV 3078 Query: 1376 QLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFE 1435 +L K +++ E+K L + + L L I Q+ + Q E Sbjct: 3079 ELSKKD----QAIKNLQIQMSALESKNLHVVNDLNL----IQQREATLNTQVKQLVQENS 3130 Query: 1436 NVRQQLV-------EYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLI 1488 +R Q + I++ KE L + L ++ N + K+S IE+VK Sbjct: 3131 QLRAQKIISDASQMNLSALIKENQILKEQHLTKIALIKYQVKNLFNHELKQS-IEKVK-- 3187 Query: 1489 EELNVKITESVSLNKQVAELNKALEEEVAKTNEMQT 1524 + + + L+ + L + L+EE +K +QT Sbjct: 3188 ---QISLQKEQQLHATIQILQQQLQEEKSKYESLQT 3220 Score = 105 bits (252), Expect = 1e-20 Identities = 242/1238 (19%), Positives = 515/1238 (41%), Gaps = 106/1238 (8%) Query: 387 SQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKD 446 S S+ L T+ I EI ++ I N + YV K+ Sbjct: 1881 SNNQSQVLLIQTESNIKDFEIKNIKEKILEENNSDNNSSYVHKYKEPNYSSAKKQ----- 1935 Query: 447 TLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQE-QLKQELN----DEIKDVNVKDL 501 I QL EH + +E + + TN + V+ QL+ N + +D V D+ Sbjct: 1936 --IEQLN-EHVRTLEKQNQLLQSTNRNQSSTSLDVKNYQLESHSNFISPNSKQDRFVNDI 1992 Query: 502 IEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQ-KTIDNFSKVSDSNKEIVRL 560 + + K I QL D+I N I +K N Q+Q K + +++ +++ + + Sbjct: 1993 LYENKQLSISIKQLEDKIQ--NYRYIDIKYN------QLQTKVVLLANQLEQTSQFLEQR 2044 Query: 561 TEELHHLSQKVAELEEEKGNLQLHLVDYDS----GRMIESDVYKKMIEM-ENLAETRLK- 614 E L QK +LE++ NLQ L GR I+ DV+++ ++ +++ + L+ Sbjct: 2045 GFESQELKQKYFKLEQDYINLQKTLYSLKGQNTQGRSIQ-DVFEEQVKQYQSVEKQNLQY 2103 Query: 615 AISLLESQKFDLVQELHI--LQQKYDEVED-KLADISQLQSDQVCSEIKSVHLEEQIDAL 671 I + E ++ L Q+ + LQQKY+ E + ++ L+ + ++K ++Q + L Sbjct: 2104 KIQIRELEELSLKQQEQLTQLQQKYNNQEQTQQINLKFLKDENSSLKVKLQEEQQQKELL 2163 Query: 672 S---------ASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTD 722 K++ +I+ + +QL +DL K +++ + EN+ L Sbjct: 2164 RNIQDNKQVPLLKQQAQQMIDQITKLSDQLKVKDQDLIKAKNNLLEIQYSQQNENIQLKQ 2223 Query: 723 KLEKMSAE------KISELLAKIN---HEEQSKIQTQFGIDAKIQERDLYIENIESELSK 773 KL++ K ++ A+ N + + Q D KIQ+ + I+N E K Sbjct: 2224 KLQESELNLQYWKTKCADTEAEKNMWISQYNQSVLNQIAQDKKIQDSKIEIDNQHKEYLK 2283 Query: 774 YKSRICRLEESIAVMEDRRYSLERK--ADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLM 831 + + E + + LE K ++Q+ L+E ++ + +D+ + L + Sbjct: 2284 VQIDEQKKEVDSLKILNSNLQLENKILSEQINQ-LKESVTSFQYKSQFKDQYLGSL--IR 2340 Query: 832 DHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAES 891 D +++ Q++ E++ K L K N +EE NL+ +++ + + +E +T Sbjct: 2341 DLEQL--NQIVRQENQEK-LSKSN---IEEQLNLEQGRNEILRKHCQELELKIKTTQNNL 2394 Query: 892 ESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEF-NTQIESAIRDKKVLNEKY 950 S + D E +KR + Q V+ + N +I+ I+ + +N Sbjct: 2395 GSNQSIESTEDTEK-VKRNKKQKQNKQVELDNNSNTVRSNSKNEEIQKYIQQQDQINN-L 2452 Query: 951 EKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINE 1010 EK I + E+Q Q+ + I+ LN + +L NLEL DK K + + Q N+ Sbjct: 2453 EKQILQLQIYESQDQQNQIRIKELNEKINQLQLQNLELEDKIKLKSKVDTMLSANQNQNQ 2512 Query: 1011 IN--KLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTT--KLENMEEEMQR 1066 + K+ LL Q +E LN+ IN+ ++ + +Q T L+ EE+ + Sbjct: 2513 EDEKKMIDLLVQIEE----LNKIINSQNSKEQQLIEENSLLKSQLKTLQDLQIQNEELVK 2568 Query: 1067 VSKQLLDSKQHNEE----LQILVREQDDQIK-ELKETKLTFEMNIPKTEGMIISSTIEPM 1121 K + KQ E+ L ++ + + Q K +++E ++T + N+ K + S ++ + Sbjct: 2569 FQKNYIKEKQIIEDRLKDLDQVIEKNNSQYKNKIEEQRITIK-NLEKRIDLFKSQSVNNI 2627 Query: 1122 SDDAN-NVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLET 1180 D N D +VQ+ + ++ V +Q N++L+ + ++ + Sbjct: 2628 KDKTNFEQDFYSIQNINAEYSQQVQKLKNELEVLQVKYKQLQVDNSQLKVQSEQQNKVYS 2687 Query: 1181 LNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWK 1240 N + G Q Q+NQ SK+ L EN VA+ + S + + + Sbjct: 2688 QNKKEFGE---LQFQLNQANSKV--LLLENQIKQKIVADNDNEKQSDTIKGN----DYFS 2738 Query: 1241 QHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQ 1300 L + +A+F+ + +L ++ K + L+ +Q++ KI+ +Q L+N+ + Sbjct: 2739 SELIKLQAEFKNQDKKLEIE------KNQNLI--LQNNIIN-LQKIINQKQ-QELKNEKE 2788 Query: 1301 DKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYK 1360 + L++ +I Q + L+ +I ++ + ++ + + Y+ Sbjct: 2789 ESNTKFNLLEQNVNGLIQQNQSLKQQISEKTQSLQVLQNNYDQATKKLKEKMQVQ-ELYE 2847 Query: 1361 QMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKT 1420 + Q Q + + +++A L++ D E+++ Q+ E+ K Sbjct: 2848 KQQNQ-LNQLIQDSACLQQELSRSKEEFNKKVQEQIDLESQIFNYKEQIF--KLELQLKK 2904 Query: 1421 HEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKES 1480 ++ + + + ++ Q ++R +DL + + + +++ ++ + + Sbjct: 2905 YQSNLNVDNISSASNTLQDQ---NDQRSQDLLNQIQ-RINSQNMQLKQSLDLVIEQNNKL 2960 Query: 1481 EIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEI 1540 E + ++N + + + +++L E+ K+ ++ N E++I L D+I Sbjct: 2961 ADEVLLQKNQMNSMNQQILQYQQTISQLEDEQNEKTKKSKKIDMHSNNLELQIRELEDQI 3020 Query: 1541 TNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNK 1578 + +V + ++ + +S Q+D K Sbjct: 3021 RSKDLLVNSIQLELDNYRITSSQKLSSIQNQVDEKTKK 3058 Score = 101 bits (241), Expect = 2e-19 Identities = 249/1328 (18%), Positives = 563/1328 (42%), Gaps = 154/1328 (11%) Query: 141 LGDVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXX 200 + +T LS+ +K KD L +K K +L++Q +++++ I+ K K Sbjct: 2183 IDQITKLSDQLKVKDQDL----IKAK---NNLLEIQ--YSQQNENIQLKQKLQESELNLQ 2233 Query: 201 XXXXXXXXXXXEDTK--QQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANK 258 E Q + N IA + + +D K + D + K+ ++E K Sbjct: 2234 YWKTKCADTEAEKNMWISQYNQSVLNQIAQDKKIQDSKIEI--DNQHKEYLKVQIDEQKK 2291 Query: 259 LLEAARF---EISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQ--SIEPSCEEKTEIEEK 313 +++ + + LE+ L++++ Q + S+ E+ +I + Sbjct: 2292 EVDSLKILNSNLQLENKILSEQINQLKESVTSFQYKSQFKDQYLGSLIRDLEQLNQIVRQ 2351 Query: 314 GSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTE---SKAVSSPSKKGSPLI 370 + E + + + +++ L + N +R+ +ELE K+ T ++++ S Sbjct: 2352 ENQEKLSKSNIEEQLNLEQGRNEILRKHCQELELKIKTTQNNLGSNQSIESTEDTEKVKR 2411 Query: 371 SRKSGRNTASKMKSPWSQLSSETLNQDTDKKINK-NEIAKLEMVIQSLN----------- 418 ++K +N ++ + + + S + N++ K I + ++I LE I L Sbjct: 2412 NKKQKQNKQVELDNNSNTVRSNSKNEEIQKYIQQQDQINNLEKQILQLQIYESQDQQNQI 2471 Query: 419 --KDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVN 476 K+L +K + ++ DT+++ Q ++Q+ + +I + E++N Sbjct: 2472 RIKELNEKINQLQLQNLELEDKIKLKSKVDTMLSANQNQNQE--DEKKMIDLLVQIEELN 2529 Query: 477 EIAKVQEQLKQELNDE----------IKDVNV---------KDLIEKLKSAEEQITQLND 517 +I Q +Q+L +E ++D+ + K+ I++ + E+++ L+ Sbjct: 2530 KIINSQNSKEQQLIEENSLLKSQLKTLQDLQIQNEELVKFQKNYIKEKQIIEDRLKDLDQ 2589 Query: 518 EIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSN-KEIVRLTEELHHL-------SQ 569 I+ N ++ +K ++K ID F S +N K+ ++ + + SQ Sbjct: 2590 VIEKNNSQYKNKIEEQRITIKNLEKRIDLFKSQSVNNIKDKTNFEQDFYSIQNINAEYSQ 2649 Query: 570 KVAELEEEKGNLQLHL--VDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLV 627 +V +L+ E LQ+ + D+ ++ + + +N E L ++ L+ Sbjct: 2650 QVQKLKNELEVLQVKYKQLQVDNSQLKVQSEQQNKVYSQNKKEFGELQFQLNQANSKVLL 2709 Query: 628 QELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLE-EQIDALSASKKELALVIENLK 686 E I Q+ + +++ + +D SE+ + E + D +K L+++N Sbjct: 2710 LENQIKQKIVADNDNEKQSDTIKGNDYFSSELIKLQAEFKNQDKKLEIEKNQNLILQNNI 2769 Query: 687 LDKEQLYGTIK-DLENDKEDIMNKLQNYIQENMD----LTDKLEKMSAEKISELLAKINH 741 ++ +++ + +L+N+KE+ K N +++N++ L++ +EK L N+ Sbjct: 2770 INLQKIINQKQQELKNEKEESNTKF-NLLEQNVNGLIQQNQSLKQQISEKTQSLQVLQNN 2828 Query: 742 EEQS------KIQTQFGIDAKIQERDLYIEN---IESELSKYKSRICR-------LEESI 785 +Q+ K+Q Q + + + + I++ ++ ELS+ K + LE I Sbjct: 2829 YDQATKKLKEKMQVQELYEKQQNQLNQLIQDSACLQQELSRSKEEFNKKVQEQIDLESQI 2888 Query: 786 AVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQED------ELVNRLAVLMDHDRVVEK 839 +++ + LE + + S L + + T+Q+ +L+N++ + + +++ Sbjct: 2889 FNYKEQIFKLELQLKKYQSNLNVDNISSASNTLQDQNDQRSQDLLNQIQRINSQNMQLKQ 2948 Query: 840 QL-LEIEHENK----ELQKKNQILLEENQNLQI--SLSDMQQHYNALVEKANRTDLAESE 892 L L IE NK L +KNQ+ Q LQ ++S ++ N +K+ + D+ Sbjct: 2949 SLDLVIEQNNKLADEVLLQKNQMNSMNQQILQYQQTISQLEDEQNEKTKKSKKIDM---H 3005 Query: 893 STKYQTQLRDLESNLKR---ITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEK 949 S + Q+R+LE ++ + + Q + + Q++ + + L + Sbjct: 3006 SNNLELQIRELEDQIRSKDLLVNSIQLELDNYRITSSQKLSSIQNQVDEKTKKVEKLEQI 3065 Query: 950 YEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELID--KHVQKQQTQSPDYTEQY 1007 Y+++ + + +L + I+NL + + L NL +++ +Q+++ +Q Sbjct: 3066 YQESEKNFQKHLVELSKKDQAIKNLQIQMSALESKNLHVVNDLNLIQQREATLNTQVKQL 3125 Query: 1008 INEINKLNALLKQKDEEIIALNQKINNAQV---SYMSMVSDYESKLAQ-FTTKLENMEEE 1063 + E ++L A D + L+ I Q+ +++ ++ + ++ F +L+ E+ Sbjct: 3126 VQENSQLRAQKIISDASQMNLSALIKENQILKEQHLTKIALIKYQVKNLFNHELKQSIEK 3185 Query: 1064 MQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEP--- 1120 ++++S Q +Q + +QIL ++ ++ + + + T+ K++ I + ++ Sbjct: 3186 VKQISLQ--KEQQLHATIQILQQQLQEEKSKYESLQTTYTSRNKKSQEHINADELKQNQI 3243 Query: 1121 -MSDDANNVDXXXXXXXXXXXXLKVQEE----EEFIQERSV--LQEQSAKLNT-EL---- 1168 +S+ + D +V + ++FI+E SV LQ Q N+ EL Sbjct: 3244 IISNKYQSTDLILDPQQIFSTLSQVVNDNTSLKKFIEEMSVKILQMQETLHNSLELLWKE 3303 Query: 1169 QECYTKI---IQLETLNTELTGHDVVNQ-----EQINQLKSKLEQLNTENDNLLSTVAEL 1220 Q + Q E N+ + H + Q + +NQLK ++ N + NL + Sbjct: 3304 QNVFMSCNLDTQEEQTNSSIQHHQIEKQVKQIIQNLNQLKMHKDEQNVSSGNLNYQDSSS 3363 Query: 1221 RSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELR--VQLSAFESKYEQLLDSVQSS 1278 A++++ + L Q Q T+ EL VQ F K +LL + + Sbjct: 3364 LPISLQAINKQQEDDGNNQSCLLKQITQFTQYTQQELENVVQQIEFLEKQNKLLKNQLQN 3423 Query: 1279 TQEETNKI-----VTMEQV------TSLQNKLQDKE-EHLRNLQEKYADVINQIEILRSE 1326 TQ+E NK+ V EQ T L + + +E E + L+E+ +++ Q+ Sbjct: 3424 TQKENNKLLIELKVVKEQYINTKYSTILHSSIMKQEGEQSQELKEQNQNILQQLSNTNIS 3483 Query: 1327 IEDEKVAF 1334 E++K+ + Sbjct: 3484 -EEQKIVY 3490 Score = 84.2 bits (199), Expect = 3e-14 Identities = 203/1054 (19%), Positives = 452/1054 (42%), Gaps = 112/1054 (10%) Query: 151 IKEK-DNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKN--KATTXXXXXXXXXXXXX 207 +K K D LS Q + + E ++DL +I E ++II ++N + Sbjct: 2496 LKSKVDTMLSANQNQNQEDEKKMIDLLVQIEELNKIINSQNSKEQQLIEENSLLKSQLKT 2555 Query: 208 XXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISS-LEEANKLLEAARFE 266 + +++ K Q+N+I + +D + L + IE + + + +EE ++ Sbjct: 2556 LQDLQIQNEELVKFQKNYIKEKQIIEDRLKDLDQVIEKNNSQYKNKIEEQRITIKNLEKR 2615 Query: 267 ISLEHSKLAQELEQXXXXXXXXXXXXXXLAK--QSIEPSCEEKTEIEEK-GSLEIANMTE 323 I L S+ ++ A+ Q ++ E ++ K L++ N ++ Sbjct: 2616 IDLFKSQSVNNIKDKTNFEQDFYSIQNINAEYSQQVQKLKNELEVLQVKYKQLQVDN-SQ 2674 Query: 324 LTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMK 383 L + E + Q ++ EL+ +L SK + ++ +++ + +K Sbjct: 2675 LKVQSEQQNKVYSQNKKEFGELQFQLNQ--ANSKVLLLENQIKQKIVADNDNEKQSDTIK 2732 Query: 384 ------SPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVI-SEKDTXXX 436 S +L +E NQD +I KN+ L+ I +L K + K+ + +EK+ Sbjct: 2733 GNDYFSSELIKLQAEFKNQDKKLEIEKNQNLILQNNIINLQKIINQKQQELKNEKEESNT 2792 Query: 437 XXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLK-QELNDEIKD 495 + LI Q Q QQ E + V N D K++E+++ QEL ++ ++ Sbjct: 2793 KFNLLEQNVNGLIQQNQSLKQQISEKTQSLQVLQNNYD-QATKKLKEKMQVQELYEKQQN 2851 Query: 496 VNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKS---NHK-------LKLKQMQKT-- 543 + LI+ ++++++ +E + + I ++S N+K L+LK+ Q Sbjct: 2852 -QLNQLIQDSACLQQELSRSKEEFNKKVQEQIDLESQIFNYKEQIFKLELQLKKYQSNLN 2910 Query: 544 IDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQ--LHLVDYDSGRMIESDVYKK 601 +DN S S++ ++ + + L ++ + + L+ L LV + ++ + + +K Sbjct: 2911 VDNISSASNTLQD--QNDQRSQDLLNQIQRINSQNMQLKQSLDLVIEQNNKLADEVLLQK 2968 Query: 602 --MIEMENLAETRLKAISLLESQKFDLVQ-----ELHI--LQQKYDEVEDK------LAD 646 M M + IS LE ++ + + ++H L+ + E+ED+ L + Sbjct: 2969 NQMNSMNQQILQYQQTISQLEDEQNEKTKKSKKIDMHSNNLELQIRELEDQIRSKDLLVN 3028 Query: 647 ISQLQSD--QVCSEIKSVHLEEQIDALSASKKELALVIENLK-------LDKEQLYGTIK 697 QL+ D ++ S K ++ Q+D + ++L + + + ++ + IK Sbjct: 3029 SIQLELDNYRITSSQKLSSIQNQVDEKTKKVEKLEQIYQESEKNFQKHLVELSKKDQAIK 3088 Query: 698 DLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKI---QTQFGID 754 +L+ + +K ++ +++L + E ++ +L+ + + KI +Q + Sbjct: 3089 NLQIQMSALESK-NLHVVNDLNLIQQREATLNTQVKQLVQENSQLRAQKIISDASQMNLS 3147 Query: 755 AKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYS 814 A I+E + E ++++ K ++ L + + S+E K Q+ LQ++Q+ ++ Sbjct: 3148 ALIKENQILKEQHLTKIALIKYQVKNLFN-----HELKQSIE-KVKQIS--LQKEQQLHA 3199 Query: 815 EYTIQEDELVNRLAVLMD-HDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQ 873 I + +L + + EH N + K+NQI++ + D Q Sbjct: 3200 TIQILQQQLQEEKSKYESLQTTYTSRNKKSQEHINADELKQNQIIISNKYQSTDLILDPQ 3259 Query: 874 QHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFN 933 Q ++ L + N + + ++ ++ L H +L + K++ + + Sbjct: 3260 QIFSTLSQVVNDNTSLKKFIEEMSVKILQMQETL------HNSLELLWKEQNVFMSCNLD 3313 Query: 934 TQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKN--NIENLNMNVEELNKM--NLELI 989 TQ E + + + + EK ++ + Q QL+ +K+ N+ + N+N ++ + + +L+ I Sbjct: 3314 TQEEQT--NSSIQHHQIEKQVKQIIQNLNQLKMHKDEQNVSSGNLNYQDSSSLPISLQAI 3371 Query: 990 DKHVQ----------KQQTQSPDYTEQYI-NEINKLNALLKQKD--EEIIALNQKINNAQ 1036 +K + KQ TQ YT+Q + N + ++ L KQ + + QK NN Sbjct: 3372 NKQQEDDGNNQSCLLKQITQFTQYTQQELENVVQQIEFLEKQNKLLKNQLQNTQKENNKL 3431 Query: 1037 VSYMSMVSD-----------YESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILV 1085 + + +V + + S + Q + + ++E+ Q + +QL ++ E+ + + Sbjct: 3432 LIELKVVKEQYINTKYSTILHSSIMKQEGEQSQELKEQNQNILQQLSNTNISEEQKIVYL 3491 Query: 1086 REQDDQIKELKETKLTFEMNIPKTEGMIISSTIE 1119 Q+ Q+ E+ + TF++N K + SS I+ Sbjct: 3492 MMQNKQLIEMIK---TFQINEAKRSEQLNSSNIQ 3522 Score = 56.4 bits (130), Expect = 6e-06 Identities = 162/822 (19%), Positives = 350/822 (42%), Gaps = 90/822 (10%) Query: 212 EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEE-ANKLLEAARFEISLE 270 E K Q +Q N I ++ ++Q L + E + + + LE+ N L++ + Sbjct: 2756 EIEKNQNLILQNNIINLQKIINQKQQELKNEKEESNTKFNLLEQNVNGLIQ--------Q 2807 Query: 271 HSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIEL 330 + L Q++ + K+ +EK +++E + + +L + Sbjct: 2808 NQSLKQQISEKTQSLQVLQNNYDQATKK-----LKEKMQVQELYEKQQNQLNQLIQDSAC 2862 Query: 331 L-EHLNCQIRQTNK------ELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMK 383 L + L+ + NK +LE+++ + + KK ++ + + ++ ++ Sbjct: 2863 LQQELSRSKEEFNKKVQEQIDLESQIFNYKEQIFKLELQLKKYQSNLNVDNISSASNTLQ 2922 Query: 384 SPWSQLSSETLNQDTDKKINKNEI---AKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXX 440 Q S + LNQ ++IN + L++VI+ NK L D+ V+ +K+ Sbjct: 2923 DQNDQRSQDLLNQ--IQRINSQNMQLKQSLDLVIEQNNK-LADE--VLLQKNQMNSMNQQ 2977 Query: 441 XXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQE------LNDEIK 494 + T I+QL+ E + + I + +N ++ +I ++++Q++ + + E+ Sbjct: 2978 ILQYQQT-ISQLEDEQNEKTKKSKKIDMHSNNLEL-QIRELEDQIRSKDLLVNSIQLELD 3035 Query: 495 DVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSN---HKLKLKQMQKTIDN----F 547 + + +KL S + Q+ + +++ + + + N H ++L + + I N Sbjct: 3036 NYRITS-SQKLSSIQNQVDEKTKKVEKLEQIYQESEKNFQKHLVELSKKDQAIKNLQIQM 3094 Query: 548 SKVSDSNKEIVR----LTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMI 603 S + N +V + + L+ +V +L +E L+ + D+ +M S + K Sbjct: 3095 SALESKNLHVVNDLNLIQQREATLNTQVKQLVQENSQLRAQKIISDASQMNLSALIK--- 3151 Query: 604 EMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVED-KLADISQLQS-----DQVCS 657 E + L E L I+L++ Q +L H L+Q ++V+ L QL + Q Sbjct: 3152 ENQILKEQHLTKIALIKYQVKNLFN--HELKQSIEKVKQISLQKEQQLHATIQILQQQLQ 3209 Query: 658 EIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIK----DLENDKEDIMNKLQNY 713 E KS + Q S +KK + + +L + Q+ + K DL D + I + L Sbjct: 3210 EEKSKYESLQTTYTSRNKKSQEHINAD-ELKQNQIIISNKYQSTDLILDPQQIFSTLSQV 3268 Query: 714 IQENMDLTDKLEKMSAEKISELLAKINHE-----EQSKIQTQFGIDAKIQERDLYIENIE 768 + +N L +E+MS KI ++ +++ ++ + +D + ++ + I++ + Sbjct: 3269 VNDNTSLKKFIEEMSV-KILQMQETLHNSLELLWKEQNVFMSCNLDTQEEQTNSSIQHHQ 3327 Query: 769 SELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLA 828 E + K I L + +++ S Q S L +A ++ QED+ N+ Sbjct: 3328 IE-KQVKQIIQNLNQLKMHKDEQNVSSGNLNYQDSSSLPISLQAINKQ--QEDDGNNQSC 3384 Query: 829 VLMDHDRVVE--KQLLE--------IEHENKELQKKNQILLEENQNLQISLSDMQQHYNA 878 +L + + +Q LE +E +NK L+ + Q +EN L I L +++ Y Sbjct: 3385 LLKQITQFTQYTQQELENVVQQIEFLEKQNKLLKNQLQNTQKENNKLLIELKVVKEQY-- 3442 Query: 879 LVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIES 938 + T L S + Q ++L+ + I + + ++++I L ++ N Q+ Sbjct: 3443 -INTKYSTILHSSIMKQEGEQSQELKEQNQNILQQLSNTNISEEQKIVYLMMQ-NKQLIE 3500 Query: 939 AIRDKKVLNEKYEKNIEYVT-QLEAQLQEYKNNIENLNMNVE 979 I+ ++ K + + QL L++ N ++ N N E Sbjct: 3501 MIKTFQINEAKRSEQLNSSNIQLYMALKDIA-NFKSKNFNFE 3541 >UniRef50_UPI00015A6057 Cluster: UPI00015A6057 related cluster; n=1; Danio rerio|Rep: UPI00015A6057 UniRef100 entry - Danio rerio Length = 1894 Score = 142 bits (345), Expect = 5e-32 Identities = 255/1308 (19%), Positives = 560/1308 (42%), Gaps = 101/1308 (7%) Query: 313 KGSLEIAN-MTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLIS 371 +G +E A +TE +K EH+ RQ K+ E+++ K + + + + L Sbjct: 534 RGQVEEAEKLTEELRKEN--EHMR---RQREKQEEDRIQQDRERHKRMEAEMLESAQLCE 588 Query: 372 RKSGRNTASKMKSPWSQLSSETLNQ---DTDKKINKNEIAKLE--MVIQSLNKDLVDKEY 426 R+S T ++ L ETL++ + + + K+ + K ++ QS ++ + +E Sbjct: 589 RES--RTRLELHRLQVALERETLDRARAEQEAEQAKDALIKARESLLAQSSGQNQLKREL 646 Query: 427 VISEKDTXXXXXXXXXXGKDTL---IAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQE 483 + KD + LQL Q L V ++ + A++Q Sbjct: 647 AGAGDALEKMAALNEALAKDKRELGVRSLQLTEQCSTVMKELQSVKV---ELLKAAELQR 703 Query: 484 QLKQELNDEIKDVN-VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQK 542 + ++E +D +++ ++D + L+ +E++ Q+ +E+ + + + ++++ + + Q ++ Sbjct: 704 RAERERDDLMRESQRLEDTVCTLEREKEELAQVKEELRYSQREIQCLQTDLERETAQKER 763 Query: 543 TIDNFSKVSDSNKEIVRLTEELHHLSQKV-----AELEEEKGNLQLHLVDYDSGRMIESD 597 + + S+++K ++ QK AEL ++ G +++ L + G + E + Sbjct: 764 ELQESIEESENSKIQAEESKTDRERWQKERESLSAELGQKDGEVEI-LRNRIDGLLKEKE 822 Query: 598 VYKKMIEMENLAETRLKAISLLESQKFDL-----VQELHILQQKYDEVEDKLADISQLQS 652 +E N +L+ S E + +L E+ +++ ++V+ + +++Q Sbjct: 823 ELLDHLEKRNTELEKLQTKSAAEQKAAELRLRGACDEVERWKERENKVQREKEELNQKFL 882 Query: 653 DQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQN 712 ++V E +++ + ++ K +++ +++ + +KE L ++ LE + K + Sbjct: 883 ERVERESQNLEITQR------EKAKMSDLMKKKEDEKETLESRVETLEKLNTQLKEKKLD 936 Query: 713 YIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERD---LYIENIES 769 I+EN K ++ EK ++ +++ I+ + ID I E++ L +E E Sbjct: 937 KIRENESRQKKRDEQEREKEVRWRRQLEQKDEGLIELKSRIDELIGEKEHISLLVEEREK 996 Query: 770 ELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAV 829 ++ + +S + +E ++ R E K +QL L E+ + + E VNR Sbjct: 997 DIEQLQSTLSTEKEREEEVQKR----EEKNEQL-ELLNEQISQIKKLKAEHAE-VNRCKA 1050 Query: 830 LMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLA 889 + + L E + E ++ QK + + E + L++ + ++ Q +E+ R + Sbjct: 1051 KIAEMEQDQVNLKERDEEQRKRQKMEKDV--EVRQLKLKIEELNQE----IEQDRRIRME 1104 Query: 890 ESESTKYQTQL-RDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNE 948 + E + QT L RD E + + Q QK KE D + + ++ +++K L+E Sbjct: 1105 QQEDLEQQTALLRDAEEEARTLKKTLQ----QKDKEERD-RLHHEEKEKTLLKEK--LHE 1157 Query: 949 KYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLEL-IDKHVQKQQTQSPDYTEQY 1007 ++NI+ ++ L+ + L E L + N EL + K + Q+ +S + + Sbjct: 1158 AEQRNIKVLSSLQEIETTLEKERYQLRGKEERLMECNEELFLIKRERDQEKESIEELNKL 1217 Query: 1008 INEINK----LNALLKQKDEEIIALNQKINNAQVSYM---SMVSDYESKLAQFTTKLENM 1060 I E K L L ++ EE L++ + N +V S + E + Q L + Sbjct: 1218 IGEQGKEVKTLRGKLDERLEEEGRLSKLLQNQRVEVQVLESRAENIEEEKQQLKRSLSQI 1277 Query: 1061 EEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEP 1120 EEE + + QL D K E L++ + +Q ++ +L K+ E K ++ +S +E Sbjct: 1278 EEEKRHLETQLTDEKVDKERLRVRLEDQATEVTKLN--KILEEER--KLSQLLQNSRVEA 1333 Query: 1121 MSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLET 1180 ++ + ++++EE + + Q++++ ++ E + I++E Sbjct: 1334 QMFESRAQNTEEEKQLLKRSLSQIEKEERKLSQLL----QNSRVEAQMLESRAENIEVEK 1389 Query: 1181 LNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWK 1240 + + + +E+ L ++L + + L + V + + ++ ++ I E + Sbjct: 1390 QQLKRSLTQI--EEEKRHLGTQLTDEKMDKERLRAWVEDQATEVTKLKEKLSEMIEE--E 1445 Query: 1241 QHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQ 1300 + L+Q + + H L + E + +QL +S TQ E K T L ++ Sbjct: 1446 RKLSQLLQNSRVEAHILESRTENIEEEKQQL---TRSLTQIEKEK---RHLETQLTDEKM 1499 Query: 1301 DKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYK 1360 DKE L+++ +V E L IE+E+ + R EN + Sbjct: 1500 DKERLRARLKDQATEVTKLKEKLNEMIEEER---KLSQLLQNSRVEAQMLESRAENTIEE 1556 Query: 1361 QMQEQSILN-INEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQL------ELKD 1413 + Q + +L+ + EE L+ R+ D +V +L +L E K Sbjct: 1557 KQQLKRVLSQVEEEKRLLETQLTDEKIDRERLKARLEDQATEVTKLKEKLNKMVEDERKL 1616 Query: 1414 SEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHY 1473 S + Q + T L R + E +QQL +IE+ E++L ++ Sbjct: 1617 SHLLQNSQVETQMLESRTENLEEEKQQLKRSLTQIEEEKRCLETQLTDEKIDRERLRARL 1676 Query: 1474 ETMQKESEIERVK-LIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIE 1532 E Q S + K E L+V++ SL +Q+ L+++ E+ K E + + Sbjct: 1677 EDFQISSLLSDAKERKESLSVQVD---SLQEQLVSLSRSKEQTKLKIQEQKEQNKEMREG 1733 Query: 1533 IVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKEL 1580 +V E+ L+ ++ S + ++ S ++ + E L+ T+ ++ Sbjct: 1734 LVAGLQEMATLKELLEESHREGERLRSMMQMLEKQKQE-LETTLQLQV 1780 Score = 122 bits (294), Expect = 8e-26 Identities = 211/1119 (18%), Positives = 479/1119 (42%), Gaps = 97/1119 (8%) Query: 147 LSNTIKEKDNALSVLQVKMKIM---ETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXX 203 LS + +KD + +L+ ++ + + +LD EK N + + ++ K+ A Sbjct: 796 LSAELGQKDGEVEILRNRIDGLLKEKEELLDHLEKRNTELEKLQTKSAAEQKAAELRLRG 855 Query: 204 XXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAA 263 ++ + ++ + +E E + + + L+ + + ++S L + K E Sbjct: 856 ACDEVERWKERENKVQREKEELNQKFLERVERESQNLEITQREKAKMSDLMK-KKEDEKE 914 Query: 264 RFEISLEH-SKLAQEL-EQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANM 321 E +E KL +L E+ +Q E + ++E+K I Sbjct: 915 TLESRVETLEKLNTQLKEKKLDKIRENESRQKKRDEQEREKEVRWRRQLEQKDEGLIELK 974 Query: 322 TELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASK 381 + + + I EH++ + + K++E +T+ TE + K+ + Sbjct: 975 SRIDELIGEKEHISLLVEEREKDIEQLQSTLSTEKEREEEVQKR---------------E 1019 Query: 382 MKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXX 441 K+ +L +E ++Q K E+ + + I + +D V+ + E+D Sbjct: 1020 EKNEQLELLNEQISQIKKLKAEHAEVNRCKAKIAEMEQDQVN----LKERDEEQRKRQKM 1075 Query: 442 XXGKDTLIAQLQL---EHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNV 498 KD + QL+L E Q +E I + ED+ + + ++E K + Sbjct: 1076 E--KDVEVRQLKLKIEELNQEIEQDRRIRM-EQQEDLEQQTALLRDAEEEARTLKKTLQQ 1132 Query: 499 KDLIEK--LKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFS-KVSDSNK 555 KD E+ L E++ T L +++ A + IKV S+ L++++ T++ ++ + Sbjct: 1133 KDKEERDRLHHEEKEKTLLKEKLHEAEQRNIKVLSS----LQEIETTLEKERYQLRGKEE 1188 Query: 556 EIVRLTEELHHLSQKVAELEEEKGNLQ-LHLVDYDSGRMIES---DVYKKMIE---MENL 608 ++ EEL + + E ++EK +++ L+ + + G+ +++ + +++ E + L Sbjct: 1189 RLMECNEELFLIKR---ERDQEKESIEELNKLIGEQGKEVKTLRGKLDERLEEEGRLSKL 1245 Query: 609 AETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADI-SQLQSDQVCSEIKSVHLEEQ 667 + + + +LES+ ++ +E L++ ++E++ + +QL ++V E V LE+Q Sbjct: 1246 LQNQRVEVQVLESRAENIEEEKQQLKRSLSQIEEEKRHLETQLTDEKVDKERLRVRLEDQ 1305 Query: 668 ------IDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLT 721 ++ + +++L+ +++N +++ + ++ E +K+ + L +E L+ Sbjct: 1306 ATEVTKLNKILEEERKLSQLLQNSRVEAQMFESRAQNTEEEKQLLKRSLSQIEKEERKLS 1365 Query: 722 DKLE--KMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRIC 779 L+ ++ A+ + I E+Q ++ I+ ++R L + + ++ K + R Sbjct: 1366 QLLQNSRVEAQMLESRAENIEVEKQQLKRSLTQIEE--EKRHLGTQLTDEKMDKERLR-- 1421 Query: 780 RLEESIAVMEDRRYSLERKADQLGSYLQEKQKA---YSEYTIQEDELVNRLAVLMDHDRV 836 A +ED+ + + ++L ++E++K ++ L +R + + + Sbjct: 1422 ------AWVEDQATEVTKLKEKLSEMIEEERKLSQLLQNSRVEAHILESRTENIEEEKQQ 1475 Query: 837 VEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKY 896 + + L +IE E + L+ + + + L+ L D L EK N + E Sbjct: 1476 LTRSLTQIEKEKRHLETQLTDEKMDKERLRARLKDQATEVTKLKEKLNEM-IEEERKLSQ 1534 Query: 897 QTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEY 956 Q +E+ + E+ Q+ K + E +E+ + D+K+ E+ + Sbjct: 1535 LLQNSRVEAQMLESRAENTIEEKQQLKRVLSQVEEEKRLLETQLTDEKIDRERLK----- 1589 Query: 957 VTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNA 1016 +LE Q E E LN VE+ K++ L + V+ Q +S TE E +L Sbjct: 1590 -ARLEDQATEVTKLKEKLNKMVEDERKLSHLLQNSQVETQMLESR--TENLEEEKQQLKR 1646 Query: 1017 LLKQKDEEIIALNQKINNAQVS---YMSMVSDYE--SKLAQFTTKLENMEEEMQRVSKQL 1071 L Q +EE L ++ + ++ + + D++ S L+ + E++ ++ + +QL Sbjct: 1647 SLTQIEEEKRCLETQLTDEKIDRERLRARLEDFQISSLLSDAKERKESLSVQVDSLQEQL 1706 Query: 1072 LDSKQHNEELQILVREQDDQIKELKETKLTF--EMNIPKT-------EGMIISSTIEPMS 1122 + + E+ ++ ++EQ +Q KE++E + EM K EG + S ++ + Sbjct: 1707 VSLSRSKEQTKLKIQEQKEQNKEMREGLVAGLQEMATLKELLEESHREGERLRSMMQMLE 1766 Query: 1123 DDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLN 1182 ++ LK ++ EE +QE+ LQ++ KL EL + E Sbjct: 1767 KQKQELETTLQLQVEQ---LK-KKNEEGMQEKEQLQQRQEKLEGELMAMKSVKEHREAEL 1822 Query: 1183 TELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELR 1221 T + ++Q +L S + + + L + +LR Sbjct: 1823 TRAKARLDILEDQRTELSSLAAERTKDAEELSNRFRDLR 1861 Score = 110 bits (264), Expect = 4e-22 Identities = 192/977 (19%), Positives = 428/977 (43%), Gaps = 92/977 (9%) Query: 141 LGDVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXX 200 +G+ H+S ++E++ + LQ + + ++Q++ EK++ +E N+ + Sbjct: 981 IGEKEHISLLVEEREKDIEQLQSTLSTEKEREEEVQKR-EEKNEQLELLNEQISQIKKLK 1039 Query: 201 XXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLL 260 + +M + Q N + E + ++Q++ KD+E + +++ +EE N+ + Sbjct: 1040 AEHAEVNRCKAKIA--EMEQDQVNLKERDEEQR-KRQKMEKDVEVRQLKLK-IEELNQEI 1095 Query: 261 EAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIAN 320 E R I +E ++LEQ L K + EE+ + E Sbjct: 1096 EQDR-RIRMEQQ---EDLEQQTALLRDAEEEARTLKKTLQQKDKEERDRLHH----EEKE 1147 Query: 321 MTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKK-GSPLISRKSGRNTA 379 T L +K+ E N ++ + +E+E L + + + L K R+ Sbjct: 1148 KTLLKEKLHEAEQRNIKVLSSLQEIETTLEKERYQLRGKEERLMECNEELFLIKRERDQE 1207 Query: 380 SKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXX 439 + ++L E Q + K + ++ + L+K L ++ + ++ Sbjct: 1208 KESIEELNKLIGE---QGKEVKTLRGKLDERLEEEGRLSKLLQNQRVEVQVLESRAENIE 1264 Query: 440 XXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVK 499 ++Q++ E ++H+E T D ++ K E+L+ L D+ +V Sbjct: 1265 EEKQQLKRSLSQIE-EEKRHLE--------TQLTD-EKVDK--ERLRVRLEDQATEVTK- 1311 Query: 500 DLIEKLKSAEEQITQL--NDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEI 557 + K+ E +++QL N ++A M + ++ + + KQ+ K + S++ +++ Sbjct: 1312 --LNKILEEERKLSQLLQNSRVEA---QMFESRAQNTEEEKQLLKR--SLSQIEKEERKL 1364 Query: 558 VRLTE----ELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRL 613 +L + E L + +E EK L+ L + E + E + + RL Sbjct: 1365 SQLLQNSRVEAQMLESRAENIEVEKQQLKRSLTQIEE----EKRHLGTQLTDEKMDKERL 1420 Query: 614 KAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSA 673 +A +E Q ++ + L++K E+ ++ +SQL + S +++ LE + + + Sbjct: 1421 RA--WVEDQATEVTK----LKEKLSEMIEEERKLSQLLQN---SRVEAHILESRTENIEE 1471 Query: 674 SKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAE--K 731 K++L + ++ +K L + D + DKE + +L++ E L +KL +M E K Sbjct: 1472 EKQQLTRSLTQIEKEKRHLETQLTDEKMDKERLRARLKDQATEVTKLKEKLNEMIEEERK 1531 Query: 732 ISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDR 791 +S+LL + S+++ Q ++ R EN E + K + ++EE ++E + Sbjct: 1532 LSQLL------QNSRVEAQM-----LESR---AENTIEEKQQLKRVLSQVEEEKRLLETQ 1577 Query: 792 RYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKEL 851 + ++L + L+++ +E T +L +L +++ +R + L + E + L Sbjct: 1578 LTDEKIDRERLKARLEDQA---TEVT----KLKEKLNKMVEDERKLSHLLQNSQVETQML 1630 Query: 852 QKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRIT 911 + + + L EE Q L+ SL+ +++ L E + + E + + + + S L Sbjct: 1631 ESRTENLEEEKQQLKRSLTQIEEEKRCL-ETQLTDEKIDRERLRARLEDFQISSLLSDAK 1689 Query: 912 HEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEY---K 968 ++L VQ ++ L+ + + S + K + E+ E+N E L A LQE K Sbjct: 1690 ERKESLSVQ----VDSLQEQLVSLSRSKEQTKLKIQEQKEQNKEMREGLVAGLQEMATLK 1745 Query: 969 NNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIAL 1028 +E + E L M +++++K QKQ+ ++ + + ++ K N Q+ E++ Sbjct: 1746 ELLEESHREGERLRSM-MQMLEK--QKQELETT--LQLQVEQLKKKNEEGMQEKEQLQQR 1800 Query: 1029 NQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQ 1088 +K+ ++ S+ E++L + +L+ +E++ +S + + EEL R+ Sbjct: 1801 QEKLEGELMAMKSVKEHREAELTRAKARLDILEDQRTELSSLAAERTKDAEELSNRFRDL 1860 Query: 1089 DDQIKELKETKLTFEMN 1105 + L+E ++ + N Sbjct: 1861 RLEADRLREDRIREKNN 1877 Score = 55.6 bits (128), Expect = 1e-05 Identities = 172/976 (17%), Positives = 378/976 (38%), Gaps = 52/976 (5%) Query: 600 KKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEI 659 KK+ E + I L+ + D L+Q+ E +L ++ D+ + Sbjct: 66 KKLREGREREARQALLIHKLQHKVLDYRARCQALEQQAVGEERELRIRERILRDERSDTL 125 Query: 660 KS--VHLEEQIDALSASKKEL-ALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQE 716 +S + LEE+ + S E+ AL+ L E DL D ++ +Q+ Sbjct: 126 ESTLIRLEEEQQSRSLGLSEVSALLRSQLSQSTEANEALRDDLRKLTADWSKAVEEVVQK 185 Query: 717 NMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENI-ESELSKYK 775 +D +K E+L +E S++ T +G ++ + ++ + +L + K Sbjct: 186 EIDW---------QKEKEVLTGYIGKEHSRLMTLWGRVVTLRRQCHSLKTATDKDLWELK 236 Query: 776 SRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDR 835 + RL S+ + S + S L + A T Q ++ L +R Sbjct: 237 ADFSRLSSSLLSVWASPLSAPKLTHN--SSLSQSTSAQPLSTTQGPLSLDDLNHEQTDER 294 Query: 836 VVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLA--ESES 893 + +IE E EL+ + + E N ++ S+ ++ + E+ +R ++ + + Sbjct: 295 KSSELKADIESETLELRNR---ITELNMTVKALESEREKQEEEM-ERRHRHEMEREQEQE 350 Query: 894 TKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKN 953 K++ Q+ +LE N + + +TL+ Q+ + E+L +F I+ K+ ++K Sbjct: 351 RKWERQM-ELERNFESVCQAVKTLVSQRIDDSENL-FQFKGAIKCIDTLFKLFSDK-SPE 407 Query: 954 IEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINK 1013 + LEA L++ + + L+ ++ VQ Q + +N+ Sbjct: 408 TSPLRSLEADDASSDGLCSVLSVIAQA--ETALQWREQEVQVDQYDIKIHRFLTSLFMNE 465 Query: 1014 LNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLD 1073 L++ E +L Q+I + ++ + Q E + + + Sbjct: 466 AQMSLRRLGTEKESLEQRITQLESEWVELQEQTNQGALQIKHTQELLNRVKLNIRHSFMM 525 Query: 1074 SKQHNEELQILVREQDDQIKEL-KETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXX 1132 SK+ + L+ V E + +EL KE + + E I +A ++ Sbjct: 526 SKKMLKNLRGQVEEAEKLTEELRKENEHMRRQREKQEEDRIQQDRERHKRMEAEMLESAQ 585 Query: 1133 XXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQL-ETLNTELTGHDVV 1191 L++ + + ER L A+ E ++ +I+ E+L + +G + + Sbjct: 586 LCERESRTRLELHRLQVAL-ERETLDR--ARAEQEAEQAKDALIKARESLLAQSSGQNQL 642 Query: 1192 NQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHL-AQREADF 1250 +E + LE++ N+ L EL +Q + EL + + A+ Sbjct: 643 KRE-LAGAGDALEKMAALNEALAKDKRELGVRSLQLTEQCSTVMKELQSVKVELLKAAEL 701 Query: 1251 QKTEHELRVQLSAFESKYEQLLDSVQSSTQE----ETNKIVTMEQVTSLQNKLQ-DKEEH 1305 Q+ R L + E + +++ +E + + ++ LQ L+ + + Sbjct: 702 QRRAERERDDLMRESQRLEDTVCTLEREKEELAQVKEELRYSQREIQCLQTDLERETAQK 761 Query: 1306 LRNLQEKYADVIN-QIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXD-LRTENQSYKQMQ 1363 R LQE + N +I+ S+ + E+ + LR + + Sbjct: 762 ERELQESIEESENSKIQAEESKTDRERWQKERESLSAELGQKDGEVEILRNRIDGLLKEK 821 Query: 1364 EQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEY 1423 E+ + ++ + N +L+K R+ A +V + + +++++ ++ E Sbjct: 822 EELLDHLEKRNTELEKLQTKSAAEQKAAELRLRGACDEV----ERWKERENKVQREKEEL 877 Query: 1424 TITLTQRNDEFENVRQQLVEYEK-RIEDLTYEKESELAILRLKMHENANHYETMQKESEI 1482 +R E E+ ++ + EK ++ DL +KE E L ++ E T KE ++ Sbjct: 878 NQKFLER-VERESQNLEITQREKAKMSDLMKKKEDEKETLESRV-ETLEKLNTQLKEKKL 935 Query: 1483 ERVKLIEELNVKITE-----SVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLN 1537 ++++ E K E V +Q+ + ++ L E ++ +E+ E+ + + Sbjct: 936 DKIRENESRQKKRDEQEREKEVRWRRQLEQKDEGLIELKSRIDELIGEKEHISLLVEERE 995 Query: 1538 DEITNLQNMVRASSSK 1553 +I LQ+ + + Sbjct: 996 KDIEQLQSTLSTEKER 1011 Score = 37.9 bits (84), Expect = 2.3 Identities = 76/412 (18%), Positives = 167/412 (40%), Gaps = 27/412 (6%) Query: 146 HLSNTIKEKDNALSVLQVKMKIMETTILDLQEKIN---EKDQIIEAKNKATTXXXXXXXX 202 HL + ++ L+ ++K T + L+EK+N E+++ + + + Sbjct: 1489 HLETQLTDEKMDKERLRARLKDQATEVTKLKEKLNEMIEEERKLSQLLQNSRVEAQMLES 1548 Query: 203 XXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEK---QRLLKDIESKDVRISSL-EEANK 258 + K+ +++++E +E + DEK +RL +E + ++ L E+ NK Sbjct: 1549 RAENTIEEKQQLKRVLSQVEEEKRLLETQLTDEKIDRERLKARLEDQATEVTKLKEKLNK 1608 Query: 259 LLEAARFEISLEHSKLAQELE-QXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLE 317 ++E R L H ++E Q K+S+ EEK +E + + E Sbjct: 1609 MVEDER---KLSHLLQNSQVETQMLESRTENLEEEKQQLKRSLTQIEEEKRCLETQLTDE 1665 Query: 318 IANMTELTKKIE--LLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSG 375 + L ++E + L ++ + L ++ ++ + ++S ++ I + Sbjct: 1666 KIDRERLRARLEDFQISSLLSDAKERKESLSVQVDSLQEQLVSLSRSKEQTKLKIQEQKE 1725 Query: 376 RNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVIS-EKDTX 434 +N + TL + ++ + E +L ++Q L K + E + + + Sbjct: 1726 QNKEMREGLVAGLQEMATLKELLEESHREGE--RLRSMMQMLEKQKQELETTLQLQVEQL 1783 Query: 435 XXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIK 494 K+ QLQ + Q+ +EG + E+ + + +L L D+ Sbjct: 1784 KKKNEEGMQEKE----QLQ-QRQEKLEGELMAMKSVKEHREAELTRAKARL-DILEDQRT 1837 Query: 495 DVNVKDLIEKLKSAEEQITQLND---EIDAANKNMIKVKSN-HKLKLKQMQK 542 +++ E+ K AEE + D E D ++ I+ K+N +LK + +K Sbjct: 1838 ELS-SLAAERTKDAEELSNRFRDLRLEADRLREDRIREKNNWEELKRENKEK 1888 >UniRef50_A2DZ81 Cluster: Viral A-type inclusion protein, putative; n=1; Trichomonas vaginalis G3|Rep: Viral A-type inclusion protein, putative - Trichomonas vaginalis G3 Length = 1547 Score = 142 bits (345), Expect = 5e-32 Identities = 258/1327 (19%), Positives = 558/1327 (42%), Gaps = 105/1327 (7%) Query: 57 AQKCLENAALVSK---RIKEHRKATAELLGRP-FVPGISESLANTLKQKEILMEKIKQYK 112 A++ EN+ V + IK+ ++ E R + ++E + L E Q K Sbjct: 140 AEESKENSKSVKQLEDEIKQLKQELDEQTNRADSLEEMNEKFRSLLPDSEDFESAYSQLK 199 Query: 113 ELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNALSVLQVKMKIMETTI 172 L + S++TI +G + +N IK+ + + L++ + + Sbjct: 200 SLCENSNSTIDDNDSEEKSHKKRHHKDLIGKLNEKNNEIKQLEKEIKSLKLTLSERSNEL 259 Query: 173 LDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEW 232 +++ + EK++ IE NK ++ ED K++ ++++ + E E Sbjct: 260 NNIRRTLAEKEEEIENLNKNSS------------NSSNEEDLKKKDEEIEK--LKEEIEK 305 Query: 233 KDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH--SKLAQELEQXXXXXXXXXX 290 + K + ++ E KD S E E + + + KL ++ + Sbjct: 306 LNSKPQKEEENEEKDKENDSEEGEENTSEKSHHKKHHKDLIGKLNKKNNEIKQLEKEIKG 365 Query: 291 XXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQ-TNKEL-ENK 348 L+++S E + +T E++ + +N L KK+E +E+L +I + NK E + Sbjct: 366 LKLTLSERSNELNNIRRTLAEKENN---SNDETLQKKVEEIENLKKEIEEFKNKSSNEEE 422 Query: 349 LATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIA 408 L ++ ++ + +K S ++ G K ++ + T + KK +K+ I Sbjct: 423 LNSLRESNQKLKEEIEKLSNKPQKEEGNEEKDK-ENDSEEGEENTSEKSHHKKHHKDLIG 481 Query: 409 KLEM---VIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSL 465 KL I+ L K++ + +SE+ K+ ++E+ ++ EG + Sbjct: 482 KLNKKNNEIKQLEKEIKSLKLTLSERSNELNNIRRTLAEKEQ-----EMENLKNGEGNT- 535 Query: 466 IHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDL-IEKLKS--AEEQITQLNDEIDAA 522 N E++N++ + + K+EL K + KD +E+++S IT+ + E+++ Sbjct: 536 ----QNNEELNQLKEDNNKQKEELESLKKQLQDKDAELEQIRSNTNTSTITEESKEMNSD 591 Query: 523 NKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQ 582 N + KS K K+ K D K++ N EI +L +E+ L ++E E N++ Sbjct: 592 NDDEESEKSQSKSGHKKHHK--DLIGKLNQKNNEIKQLEKEIKSLKLTLSERSNELNNIR 649 Query: 583 LHLVDYD----------SGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHI 632 L + + S E D+ KK E+++L E+ K L ++ + +++L Sbjct: 650 RTLTEKEQEIDNLKKSGSNSSNEEDLKKKDEEIKSLRESNDKLQKELLTRD-EEIEKLSN 708 Query: 633 LQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASK------KELALVIENLK 686 QK +E E+K + + ++ SE KS H + D + K+L I+ LK Sbjct: 709 KPQKEEENEEKDKENDSEEGEENTSE-KSHHKKHHKDLIGKLNKKNNEIKQLEKEIKGLK 767 Query: 687 LDKEQLYGTIKDLEN---DKEDIMNKLQNYIQ-ENMDLTDKLEKMSAEKISELLAKINHE 742 L + + ++ +KE M L +Q +N D +L++ + + SEL +K Sbjct: 768 LTLSERSNELNNIRRTLAEKEQEMENLNGSVQNKNDDEIKELQQENEKLKSELASKDAEL 827 Query: 743 EQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQL 802 EQ + T + + +++ +N + E S+ ++ + + + QL Sbjct: 828 EQIRSNTNTSTITE-ESKEMNSDNDDDEESEKSQSKSGHKKHHKDLIGKLNQKNNEIKQL 886 Query: 803 GSYLQEKQKAYSEYTIQEDELVNRLAVLMD--HDRVVEKQLLEIEHENKELQ--KKNQIL 858 ++ + SE + + + + LA + +D ++K+ EIE+ KE+ KK+ Sbjct: 887 EKEIKSLKLTLSERSNELNNIRRTLAEKENNSNDETLQKKEEEIENLKKEIDNLKKSSSN 946 Query: 859 LEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITH---EHQ 915 EE ++L+ + +++ + T E + E N +H H+ Sbjct: 947 EEETKSLRDEIEKLKKELESKESMNTNTSTINEEIDGEAKENDSEEENTSEKSHHKKHHK 1006 Query: 916 TLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLN 975 LI + ++ +++ Q+E I+ K+ + + + + A+ +E +N E L Sbjct: 1007 DLIGKLNQKNNEIK-----QLEKEIKSLKLTLSERSNELNNIRRTLAE-KENNSNDETLQ 1060 Query: 976 MNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQK-INN 1034 VEE+ + E+ ++ ++ E+ +N + + N LK++ E++ + QK N Sbjct: 1061 KKVEEIENLKKEI-------EEFKNKSSNEEELNSLRESNQKLKEEIEKLNSKPQKEEEN 1113 Query: 1035 AQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKE 1094 + + + E ++ + ++ ++ + +++K+ + KQ +E++ L ++ E Sbjct: 1114 EEKDKENDSEEGEENTSEKSHHKKHHKDLIGKLNKKNNEIKQLEKEIKGLKLTLSEKSNE 1173 Query: 1095 LKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQER 1154 L + T + + +E + + ++ + ++++ + Sbjct: 1174 LNNIRRTLAEKENNSNDETLQKKVEEIENLKKEINSLTESNENLKNLIDEMKKKDTTNNK 1233 Query: 1155 SVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDV-VNQEQINQLKSKLEQLNTENDNL 1213 S + K +E K + + +L D +N+EQ Q +++ TE Sbjct: 1234 SKTPVKFIKKAMSEKELSFKPMAQTVRSRDLNLTDFSLNEEQFRQEMESWKRIATER--- 1290 Query: 1214 LSTVAELRSSISSAVDQRGFEIAELWKQHLAQR----EADFQKTEHELRVQLSAFESKYE 1269 A + ++ R EI +L K+ + + + K E Q + ++ K Sbjct: 1291 ----ARENDDLRQQINSRDQEIEKLKKEEKSTNFQISKMNNDKQELAKLRQDNTYKDKEI 1346 Query: 1270 QLLDSVQSSTQEETNKIVT-MEQVTSLQNKLQ----DKEEHLRNLQEKYADVINQIEILR 1324 Q L S SS + E NK+ T ++Q + NKL+ KE ++ L++ + N+I+ L+ Sbjct: 1347 QRLLSEASSKETENNKLKTELDQKNNECNKLKTLNNSKENDIKQLKQDLSHKDNEIQALK 1406 Query: 1325 SEIEDEK 1331 +EI ++ Sbjct: 1407 NEIHSKE 1413 Score = 137 bits (332), Expect = 2e-30 Identities = 216/1096 (19%), Positives = 484/1096 (44%), Gaps = 82/1096 (7%) Query: 475 VNEIAKVQEQLKQELNDEIK-DVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNH 533 +N + + +QL DE V I +L ++++ N A+N +++ + Sbjct: 73 MNFLRTIADQLGITQQDEASLKCQVSTRIHELIKINGKMSKQNVSEVASNDPLVQNSDSE 132 Query: 534 KLKLKQM-QKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGR 592 K + + +++ +N V EI +L +EL + + LEE + L D + Sbjct: 133 SSKSQDIAEESKENSKSVKQLEDEIKQLKQELDEQTNRADSLEEMNEKFRSLLPDSE--- 189 Query: 593 MIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQS 652 D ++++L E I +S++ + H + ++ +K +I QL+ Sbjct: 190 ----DFESAYSQLKSLCENSNSTIDDNDSEEKSHKKRHH--KDLIGKLNEKNNEIKQLEK 243 Query: 653 DQVCSEIKSVHLEEQIDALSASKKELALVIENLKLD------KEQLYGTIKDLENDKEDI 706 + ++ +++ + + E IENL + +E L +++E KE+I Sbjct: 244 EIKSLKLTLSERSNELNNIRRTLAEKEEEIENLNKNSSNSSNEEDLKKKDEEIEKLKEEI 303 Query: 707 MNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAK---IQERDLY 763 KL + Q+ + +K ++ +E+ E ++ +H ++ ++ K I++ + Sbjct: 304 -EKLNSKPQKEEENEEKDKENDSEEGEENTSEKSHHKKHHKDLIGKLNKKNNEIKQLEKE 362 Query: 764 IENIESELSKYKSRICRLEESIAVMEDRRY--SLERKADQLGSYLQEKQKAYSEYTIQED 821 I+ ++ LS+ + + + ++A E+ +L++K +++ + L+++ + + + E+ Sbjct: 363 IKGLKLTLSERSNELNNIRRTLAEKENNSNDETLQKKVEEIEN-LKKEIEEFKNKSSNEE 421 Query: 822 ELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVE 881 EL + +EK + + E +K + EE + S ++H+ L+ Sbjct: 422 ELNSLRESNQKLKEEIEKLSNKPQKEEGNEEKDKENDSEEGEENTSEKSHHKKHHKDLIG 481 Query: 882 KANRTDLAESESTKYQTQLRDLESNLKRITHEHQTL---IVQKKKEIEDLEI-EFNTQIE 937 K N+ + +E + + +++ L+ L ++E + + +K++E+E+L+ E NTQ Sbjct: 482 KLNKKN---NEIKQLEKEIKSLKLTLSERSNELNNIRRTLAEKEQEMENLKNGEGNTQNN 538 Query: 938 SAIRDKKVLNEKYEKNIEYVT-QLE---AQLQEYKNNIENLNMNVEELNKMNLELIDKHV 993 + K N K ++ +E + QL+ A+L++ ++N N + EE +MN + D+ Sbjct: 539 EELNQLKEDNNKQKEELESLKKQLQDKDAELEQIRSNT-NTSTITEESKEMNSDNDDEES 597 Query: 994 QKQQTQS--PDYTEQYINEINKLNALLKQKDEEIIALNQKIN---NAQVSYMSMVSDYES 1048 +K Q++S + + I ++N+ N +KQ ++EI +L ++ N + +++ E Sbjct: 598 EKSQSKSGHKKHHKDLIGKLNQKNNEIKQLEKEIKSLKLTLSERSNELNNIRRTLTEKEQ 657 Query: 1049 KLAQFTTKLENM--EEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNI 1106 ++ N EE++++ +++ ++ N++LQ + +D++I++L E N Sbjct: 658 EIDNLKKSGSNSSNEEDLKKKDEEIKSLRESNDKLQKELLTRDEEIEKLSNKPQKEEENE 717 Query: 1107 PKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKV--QEEEEFIQERSVLQEQSAKL 1164 K + E S+ +++ Q E+E + L E+S +L Sbjct: 718 EKDKENDSEEGEENTSEKSHHKKHHKDLIGKLNKKNNEIKQLEKEIKGLKLTLSERSNEL 777 Query: 1165 NTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSI 1224 N + K ++E LN + N ++I +L+ + E+L +E + + + ++RS+ Sbjct: 778 NNIRRTLAEKEQEMENLNGSVQNK---NDDEIKELQQENEKLKSELASKDAELEQIRSNT 834 Query: 1225 SSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETN 1284 +++ I E K+ + + D E E S + ++ L+ + ++ N Sbjct: 835 NTST------ITEESKEMNSDNDDD---EESEKSQSKSGHKKHHKDLIGKLN----QKNN 881 Query: 1285 KIVTME-QVTSLQNKLQDKEEHLRNLQEKYADVINQIE---ILRSEIEDEKVAFXXXXXX 1340 +I +E ++ SL+ L ++ L N++ A+ N + + E E E + Sbjct: 882 EIKQLEKEIKSLKLTLSERSNELNNIRRTLAEKENNSNDETLQKKEEEIENLKKEIDNLK 941 Query: 1341 XXXXXXXXXXDLRTENQSYK-QMQEQSILNINEE--NAQLKKSSXXXXXXXXXXXXRVND 1397 LR E + K +++ + +N N N ++ + + + Sbjct: 942 KSSSNEEETKSLRDEIEKLKKELESKESMNTNTSTINEEIDGEAKENDSEEENTSEKSHH 1001 Query: 1398 AEAKVLELTHQLELKDSEIYQKTHEYT---ITLTQRNDEFENVRQQLVEYEKRIEDLTYE 1454 + +L +L K++EI Q E +TL++R++E N+R+ L E E D T + Sbjct: 1002 KKHHK-DLIGKLNQKNNEIKQLEKEIKSLKLTLSERSNELNNIRRTLAEKENNSNDETLQ 1060 Query: 1455 KE-SELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESV-SLNKQVAELNKAL 1512 K+ E+ L+ ++ E N K S E + + E N K+ E + LN + + + Sbjct: 1061 KKVEEIENLKKEIEEFKN------KSSNEEELNSLRESNQKLKEEIEKLNSKPQKEEE-- 1112 Query: 1513 EEEVAKTNEMQTALEN 1528 EE K N+ + EN Sbjct: 1113 NEEKDKENDSEEGEEN 1128 Score = 137 bits (332), Expect = 2e-30 Identities = 261/1316 (19%), Positives = 556/1316 (42%), Gaps = 133/1316 (10%) Query: 318 IANMTELTKKIELLEHLNCQIRQTNKEL---ENKLATMGTESKAVSSPSKKGSPLISRKS 374 IA+ +T++ E L CQ+ EL K++ A + P + S S KS Sbjct: 79 IADQLGITQQDEA--SLKCQVSTRIHELIKINGKMSKQNVSEVASNDPLVQNSDSESSKS 136 Query: 375 GRNTASKMKSPWS--QLSSET--LNQDTDKKINK-NEIAKLEMVIQSLNKDLVDKEYVIS 429 ++ S QL E L Q+ D++ N+ + + ++ +SL D D E S Sbjct: 137 QDIAEESKENSKSVKQLEDEIKQLKQELDEQTNRADSLEEMNEKFRSLLPDSEDFESAYS 196 Query: 430 EKDTXXXXXXXXXXGKDT------------LIAQLQLEH----QQHMEGPSL-IHVGTNT 472 + + D+ LI +L ++ Q E SL + + + Sbjct: 197 QLKSLCENSNSTIDDNDSEEKSHKKRHHKDLIGKLNEKNNEIKQLEKEIKSLKLTLSERS 256 Query: 473 EDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSN 532 ++N I + + ++E+ + K+ + E LK +E+I +L +EI+ N K + N Sbjct: 257 NELNNIRRTLAEKEEEIENLNKNSSNSSNEEDLKKKDEEIEKLKEEIEKLNSKPQKEEEN 316 Query: 533 -HKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSG 591 K K ++ +N S+ S K L +L+ + ++ +LE+E L+L L + + Sbjct: 317 EEKDKENDSEEGEENTSEKSHHKKHHKDLIGKLNKKNNEIKQLEKEIKGLKLTLSERSN- 375 Query: 592 RMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQ 651 E+ N+ T ++ E+ D LQ+K +E+E+ +I + + Sbjct: 376 ------------ELNNIRRT----LAEKENNSND-----ETLQKKVEEIENLKKEIEEFK 414 Query: 652 SDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGT-IKDLENDKEDIMNKL 710 + KS + EE++++L S ++L IE L ++ G KD END E+ Sbjct: 415 N-------KSSN-EEELNSLRESNQKLKEEIEKLSNKPQKEEGNEEKDKENDSEE----- 461 Query: 711 QNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESE 770 +EN +K + I +L K N +Q ++ +I+ L + +E Sbjct: 462 ---GEENTSEKSHHKKHHKDLIGKLNKKNNEIKQ--------LEKEIKSLKLTLSERSNE 510 Query: 771 LSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVL 830 L+ + + E+ + +++ + + ++L ++ K Q++EL + L Sbjct: 511 LNNIRRTLAEKEQEMENLKNGEGNTQNN-EELNQLKEDNNK-------QKEELESLKKQL 562 Query: 831 MDHDRVVEK-----QLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANR 885 D D +E+ I E+KE+ N EE++ Q S S ++H+ L+ K N+ Sbjct: 563 QDKDAELEQIRSNTNTSTITEESKEMNSDNDD--EESEKSQ-SKSGHKKHHKDLIGKLNQ 619 Query: 886 TDLAESESTKYQTQLRDLESNLKRITHEHQTL---IVQKKKEIEDLEIE-FNTQIESAIR 941 + +E + + +++ L+ L ++E + + +K++EI++L+ N+ E ++ Sbjct: 620 KN---NEIKQLEKEIKSLKLTLSERSNELNNIRRTLTEKEQEIDNLKKSGSNSSNEEDLK 676 Query: 942 DK----KVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQ 997 K K L E +K + + + ++++ N + N EE +K N + ++ Sbjct: 677 KKDEEIKSLRESNDKLQKELLTRDEEIEKLSNKPQKEEEN-EEKDKENDSEEGEENTSEK 735 Query: 998 TQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKL 1057 + + + I ++NK N +KQ ++EI L ++ + +++ LA+ ++ Sbjct: 736 SHHKKHHKDLIGKLNKKNNEIKQLEKEIKGLKLTLSERS----NELNNIRRTLAEKEQEM 791 Query: 1058 ENMEEEMQ-RVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISS 1116 EN+ +Q + ++ + +Q NE+L+ + +D ++++++ T + +++ M + Sbjct: 792 ENLNGSVQNKNDDEIKELQQENEKLKSELASKDAELEQIRSNTNTSTIT-EESKEMNSDN 850 Query: 1117 TIEPMSDDANNVDXXXXXXXXXXXXL--KVQEEEEFIQERSVLQEQSAKLNTELQECYTK 1174 + S+ + + L K E ++ +E L+ ++ + EL Sbjct: 851 DDDEESEKSQSKSGHKKHHKDLIGKLNQKNNEIKQLEKEIKSLKLTLSERSNELNNIRRT 910 Query: 1175 IIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFE 1234 + + E + + T +E+I LK +++ L + N T LR I + + Sbjct: 911 LAEKENNSNDETLQK--KEEEIENLKKEIDNLKKSSSNEEET-KSLRDEIEKLKKELESK 967 Query: 1235 IAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTME-QVT 1293 + E D + E++ + ++ +S +++ + ++ N+I +E ++ Sbjct: 968 ESMNTNTSTINEEIDGEAKENDSEEENTSEKSHHKKHHKDLIGKLNQKNNEIKQLEKEIK 1027 Query: 1294 SLQNKLQDKEEHLRNLQEKYADVINQI--EILRSEIED-EKVAFXXXXXXXXXXXXXXXX 1350 SL+ L ++ L N++ A+ N E L+ ++E+ E + Sbjct: 1028 SLKLTLSERSNELNNIRRTLAEKENNSNDETLQKKVEEIENLKKEIEEFKNKSSNEEELN 1087 Query: 1351 DLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLE 1410 LR NQ K+ E+ +E +K + + +L +L Sbjct: 1088 SLRESNQKLKEEIEKLNSKPQKEEENEEKDKENDSEEGEENTSEKSHHKKHHKDLIGKLN 1147 Query: 1411 LKDSEIYQKTHE---YTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMH 1467 K++EI Q E +TL+++++E N+R+ L E E D T +K+ E I LK Sbjct: 1148 KKNNEIKQLEKEIKGLKLTLSEKSNELNNIRRTLAEKENNSNDETLQKKVE-EIENLKKE 1206 Query: 1468 ENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALE 1527 N+ ES LI+E+ K T + V + KA+ E+ M + Sbjct: 1207 INS------LTESNENLKNLIDEMKKKDTTNNKSKTPVKFIKKAMSEKELSFKPMAQTVR 1260 Query: 1528 NQEIEIV--TLNDE--ITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKE 1579 ++++ + +LN+E +++ R ++ + +++ RD++++ +E Sbjct: 1261 SRDLNLTDFSLNEEQFRQEMESWKRIATERARENDDLRQQI-NSRDQEIEKLKKEE 1315 Score = 127 bits (307), Expect = 2e-27 Identities = 253/1206 (20%), Positives = 523/1206 (43%), Gaps = 138/1206 (11%) Query: 356 SKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQ 415 +K SS S+ SP S ++ ++ + P SQ SE D +N+ +LE+++ Sbjct: 17 TKRKSSGSEGFSPKQSSENESYSSQQDNQPESQ--SEQNVPDVCSDSERNDSQRLEILMN 74 Query: 416 SLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPS---LIH----V 468 L + + D + I+++D + + ++ Q E S L+ Sbjct: 75 FL-RTIAD-QLGITQQDEASLKCQVSTRIHELIKINGKMSKQNVSEVASNDPLVQNSDSE 132 Query: 469 GTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAA---NKN 525 + ++D+ E +K + ++L DEIK +K +++ + + + ++N++ + +++ Sbjct: 133 SSKSQDIAEESKENSKSVKQLEDEIK--QLKQELDEQTNRADSLEEMNEKFRSLLPDSED 190 Query: 526 MIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVR--LTEELHHLSQKVAELEEEKGNLQL 583 S K + TID+ S+K+ L +L+ + ++ +LE+E +L+L Sbjct: 191 FESAYSQLKSLCENSNSTIDDNDSEEKSHKKRHHKDLIGKLNEKNNEIKQLEKEIKSLKL 250 Query: 584 HLVDYDSG-RMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVED 642 L + + I + +K E+ENL + + + + +K D +E+ L+++ +++ Sbjct: 251 TLSERSNELNNIRRTLAEKEEEIENLNKNSSNSSNEEDLKKKD--EEIEKLKEEIEKLNS 308 Query: 643 KLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLEND 702 K + ++++ E S EE S KK +I KL+K+ IK LE + Sbjct: 309 K--PQKEEENEEKDKENDSEEGEENTSEKSHHKKHHKDLIG--KLNKKN--NEIKQLEKE 362 Query: 703 KEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDL 762 + L+ + E + + + + AEK E S +T + K++E Sbjct: 363 ----IKGLKLTLSERSNELNNIRRTLAEK----------ENNSNDET---LQKKVEE--- 402 Query: 763 YIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDE 822 IEN++ E+ ++K++ EE + + + L+ + ++L + Q+++ + + E Sbjct: 403 -IENLKKEIEEFKNKSSN-EEELNSLRESNQKLKEEIEKLSNKPQKEEGNEEKDKENDSE 460 Query: 823 LVNRLAVLMDHDRVVEKQLL-EIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVE 881 H + K L+ ++ +N E+++ L +E ++L+++LS+ N + Sbjct: 461 EGEENTSEKSHHKKHHKDLIGKLNKKNNEIKQ----LEKEIKSLKLTLSERSNELNNI-- 514 Query: 882 KANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIR 941 R LAE E +++E NLK E T Q +E+ L+ + N Q E Sbjct: 515 ---RRTLAEKE--------QEME-NLK--NGEGNT---QNNEELNQLKEDNNKQKEELES 557 Query: 942 DKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSP 1001 KK L +K +A+L++ ++N N + EE +MN + D+ +K Q++S Sbjct: 558 LKKQLQDK-----------DAELEQIRSN-TNTSTITEESKEMNSDNDDEESEKSQSKS- 604 Query: 1002 DYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENME 1061 + + + + I KLN QK+ EI L ++I + +++ +S+ ++L L E Sbjct: 605 GHKKHHKDLIGKLN----QKNNEIKQLEKEIKSLKLT----LSERSNELNNIRRTLTEKE 656 Query: 1062 EEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPM 1121 +E+ + K S NEE ++++D++IK L+E+ + + + I + +P Sbjct: 657 QEIDNLKKS--GSNSSNEE---DLKKKDEEIKSLRESNDKLQKELLTRDEEIEKLSNKPQ 711 Query: 1122 SDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETL 1181 ++ N +E EE E+S ++ L +L + +I QLE Sbjct: 712 KEEENEEKDKENDS---------EEGEENTSEKSHHKKHHKDLIGKLNKKNNEIKQLE-- 760 Query: 1182 NTELTGHDVVNQE---QINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAEL 1238 E+ G + E ++N ++ L + E +NL +V + Q E Sbjct: 761 -KEIKGLKLTLSERSNELNNIRRTLAEKEQEMENLNGSVQNKNDDEIKELQQEN----EK 815 Query: 1239 WKQHLAQREADFQKTEHELRVQLSAFESKY-------EQLLDSVQSSTQEETNKIVTMEQ 1291 K LA ++A+ ++ ESK ++ + QS + + + + + Sbjct: 816 LKSELASKDAELEQIRSNTNTSTITEESKEMNSDNDDDEESEKSQSKSGHKKHHKDLIGK 875 Query: 1292 VTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXD 1351 + N+++ E+ +++L+ ++ N++ +R + EK Sbjct: 876 LNQKNNEIKQLEKEIKSLKLTLSERSNELNNIRRTLA-EKENNSNDETLQKKEEEIENLK 934 Query: 1352 LRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLEL 1411 +N E+ ++ +E +LKK + + + E + E Sbjct: 935 KEIDNLKKSSSNEEETKSLRDEIEKLKKELESKESMNTNTSTINEEIDGEAKENDSEEEN 994 Query: 1412 KDSEIYQKTHEYTI--TLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILR--LKMH 1467 + + K H + L Q+N+E + + +++ K ++ E+ +EL +R L Sbjct: 995 TSEKSHHKKHHKDLIGKLNQKNNEIKQLEKEI----KSLKLTLSERSNELNNIRRTLAEK 1050 Query: 1468 ENANHYETMQKE-SEIERVKL-IEELNVKITESVSLNKQVAELNKALEEEVAKTN-EMQT 1524 EN ++ ET+QK+ EIE +K IEE K + LN + E N+ L+EE+ K N + Q Sbjct: 1051 ENNSNDETLQKKVEEIENLKKEIEEFKNKSSNEEELN-SLRESNQKLKEEIEKLNSKPQK 1109 Query: 1525 ALENQE 1530 EN+E Sbjct: 1110 EEENEE 1115 Score = 122 bits (295), Expect = 6e-26 Identities = 259/1240 (20%), Positives = 507/1240 (40%), Gaps = 153/1240 (12%) Query: 143 DVTHLSNTIKEKDNALSVLQVKMKIMETTILD--LQEKINE----KDQIIEAKNKATTXX 196 ++ L T+ E+ N L+ ++ + E D LQ+K+ E K +I E KNK++ Sbjct: 362 EIKGLKLTLSERSNELNNIRRTLAEKENNSNDETLQKKVEEIENLKKEIEEFKNKSSNEE 421 Query: 197 XXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEA 256 + K+++ K+ E + +K+ ++ E S ++ Sbjct: 422 ELNSLRESN------QKLKEEIEKLSNKPQKEEGNEEKDKENDSEEGEENTSEKSHHKKH 475 Query: 257 NKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSL 316 +K L + + E +L +E++ + + E E++ E + G Sbjct: 476 HKDLIGKLNKKNNEIKQLEKEIKSLKLTLSERSNELNNIRRTLAEK--EQEMENLKNGEG 533 Query: 317 EIANMTELT-------KKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPL 369 N EL K+ E LE L Q++ + ELE T + ++ SK+ Sbjct: 534 NTQNNEELNQLKEDNNKQKEELESLKKQLQDKDAELEQ--IRSNTNTSTITEESKE---- 587 Query: 370 ISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINK--NEIAKLEMVIQSLNKDLVDKEYV 427 + N + + S+ + ++D K+N+ NEI +LE I+SL L ++ Sbjct: 588 ---MNSDNDDEESEKSQSKSGHKKHHKDLIGKLNQKNNEIKQLEKEIKSLKLTLSERSNE 644 Query: 428 ISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLK- 486 ++ I + E +Q ++ +L G+N+ + ++ K E++K Sbjct: 645 LNN------------------IRRTLTEKEQEID--NLKKSGSNSSNEEDLKKKDEEIKS 684 Query: 487 -QELNDEI-KDVNVKDL-IEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKT 543 +E ND++ K++ +D IEKL S + Q + N+E D N + + + N K + Sbjct: 685 LRESNDKLQKELLTRDEEIEKL-SNKPQKEEENEEKDKENDSE-EGEENTSEKSHHKKHH 742 Query: 544 IDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSG-RMIESDVYKKM 602 D K++ N EI +L +E+ L ++E E N++ L + + + V K Sbjct: 743 KDLIGKLNKKNNEIKQLEKEIKGLKLTLSERSNELNNIRRTLAEKEQEMENLNGSVQNKN 802 Query: 603 I-EMENLAETRLKAISLLESQKFDLVQ-----ELHILQQKYDEVEDKLADISQLQSDQVC 656 E++ L + K S L S+ +L Q + ++ E+ D + + Q Sbjct: 803 DDEIKELQQENEKLKSELASKDAELEQIRSNTNTSTITEESKEMNSDNDDDEESEKSQSK 862 Query: 657 SEIKSVHLE---------EQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKED-I 706 S K H + +I L K L L + + + T+ + EN+ D Sbjct: 863 SGHKKHHKDLIGKLNQKNNEIKQLEKEIKSLKLTLSERSNELNNIRRTLAEKENNSNDET 922 Query: 707 MNKLQNYIQENMDLTDKLEKMSAEK-----ISELLAKINHEEQSK--IQTQFG-----ID 754 + K + I+ D L+K S+ + + + + K+ E +SK + T ID Sbjct: 923 LQKKEEEIENLKKEIDNLKKSSSNEEETKSLRDEIEKLKKELESKESMNTNTSTINEEID 982 Query: 755 AKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYS 814 + +E D EN SE S +K L + + LE++ L L E+ + Sbjct: 983 GEAKENDSEEENT-SEKSHHKKHHKDLIGKLNQKNNEIKQLEKEIKSLKLTLSERSNELN 1041 Query: 815 EYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQK-KNQILLEENQNLQISLSDMQ 873 E N +D ++K++ EIE+ KE+++ KN+ EE N SL + Sbjct: 1042 NIRRTLAEKENN-----SNDETLQKKVEEIENLKKEIEEFKNKSSNEEELN---SLRESN 1093 Query: 874 QHYNALVEKANRTDLAESESTKY--QTQLRDLESNLKRITHE---HQTLIVQKKKEIEDL 928 Q +EK N E E+ + + + E N +H H+ LI + K+ ++ Sbjct: 1094 QKLKEEIEKLNSKPQKEEENEEKDKENDSEEGEENTSEKSHHKKHHKDLIGKLNKKNNEI 1153 Query: 929 EIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLEL 988 + Q+E I+ K+ + + + + A+ +E +N E L VEE+ + E+ Sbjct: 1154 K-----QLEKEIKGLKLTLSEKSNELNNIRRTLAE-KENNSNDETLQKKVEEIENLKKEI 1207 Query: 989 IDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYES 1048 T+S + + I+E+ K + + + + + ++ ++S+ M S Sbjct: 1208 ------NSLTESNENLKNLIDEMKKKDTTNNKSKTPVKFIKKAMSEKELSFKPMAQTVRS 1261 Query: 1049 K---LAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMN 1105 + L F+ E +EM+ + + + N++L+ + +D +I++LK+ + + Sbjct: 1262 RDLNLTDFSLNEEQFRQEMESWKRIATERARENDDLRQQINSRDQEIEKLKKEEKSTNFQ 1321 Query: 1106 IPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLN 1165 I K N D K +E + + E S + ++ KL Sbjct: 1322 ISKM-----------------NNDKQELAKLRQDNTYKDKEIQRLLSEASSKETENNKLK 1364 Query: 1166 TELQECYTKIIQLETLNT-----------ELTGHDVVNQEQINQLKSK-LEQLNTENDNL 1213 TEL + + +L+TLN +L+ D Q N++ SK E + +N+ L Sbjct: 1365 TELDQKNNECNKLKTLNNSKENDIKQLKQDLSHKDNEIQALKNEIHSKENEIIKVKNEGL 1424 Query: 1214 LSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLD 1273 +++V +L+ +++ + + E K H ++ E + R + +K ++ L Sbjct: 1425 MNSVTQLQRKVAALTTDKTM-LTEEVKLHTSR--LSVLAAERKSREEEEQLMAKLKRRLI 1481 Query: 1274 SVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRN-LQEK 1312 + QE+ + +E + S KL+ + E L N L+EK Sbjct: 1482 AKDVELQEKDRQ---LEFLNSSVKKLKKENEQLNNELKEK 1518 Score = 118 bits (285), Expect = 1e-24 Identities = 243/1228 (19%), Positives = 519/1228 (42%), Gaps = 128/1228 (10%) Query: 55 ERAQKCLENAALVSKRIKEHRKATAELLGRPFVPGISESLANTLKQKEILMEKIKQYKEL 114 E QK +E + K I+E + ++ + ++ L +++ +K + +E Sbjct: 394 ETLQKKVEEIENLKKEIEEFKNKSSNEEELNSLRESNQKLKEEIEKLSNKPQKEEGNEEK 453 Query: 115 SKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNALSVLQVKMKIMETTILD 174 K + + +G + +N IK+ + + L++ + + + Sbjct: 454 DKENDSEEGEENTSEKSHHKKHHKDLIGKLNKKNNEIKQLEKEIKSLKLTLSERSNELNN 513 Query: 175 LQEKINEKDQIIE-AKN-KATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEW 232 ++ + EK+Q +E KN + T E+ + ++Q+ +E Sbjct: 514 IRRTLAEKEQEMENLKNGEGNTQNNEELNQLKEDNNKQKEELESLKKQLQDKDAELEQIR 573 Query: 233 KDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHS---KLAQELEQXXXXXXXXX 289 + + + ESK++ + +E ++ ++ KL Q+ + Sbjct: 574 SNTNTSTITE-ESKEMNSDNDDEESEKSQSKSGHKKHHKDLIGKLNQKNNEIKQLEKEIK 632 Query: 290 XXXXXLAKQSIEPS------CEEKTEIE--EKGSLEIANMTELTKKIELLEHLNCQIRQT 341 L+++S E + E++ EI+ +K +N +L KK E ++ L R++ Sbjct: 633 SLKLTLSERSNELNNIRRTLTEKEQEIDNLKKSGSNSSNEEDLKKKDEEIKSL----RES 688 Query: 342 NKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLN-QDTDK 400 N +L+ +L T E + +S+ +K K N + + + S+ S + +D Sbjct: 689 NDKLQKELLTRDEEIEKLSNKPQKEEEN-EEKDKENDSEEGEENTSEKSHHKKHHKDLIG 747 Query: 401 KINK--NEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQ 458 K+NK NEI +LE I+ L L ++ ++ I + E +Q Sbjct: 748 KLNKKNNEIKQLEKEIKGLKLTLSERSNELNN------------------IRRTLAEKEQ 789 Query: 459 HMEGPSLIHVGTNTEDVNEIAKVQEQLKQEL---NDEIKDVNVKDLIEKLKSAEEQITQL 515 ME + N +++ E+ + E+LK EL + E++ + + +++ Sbjct: 790 EMENLNGSVQNKNDDEIKELQQENEKLKSELASKDAELEQIRSNTNTSTITEESKEMNSD 849 Query: 516 NDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELE 575 ND+ + + K+ + KS HK K D K++ N EI +L +E+ L ++E Sbjct: 850 NDDDEESEKS--QSKSGHKKHHK------DLIGKLNQKNNEIKQLEKEIKSLKLTLSERS 901 Query: 576 EEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAET--RLKAISLLESQKFDLVQELHIL 633 E N++ L + ++ E+ + KK E+ENL + LK S E + L E+ L Sbjct: 902 NELNNIRRTLAEKENNSNDET-LQKKEEEIENLKKEIDNLKKSSSNEEETKSLRDEIEKL 960 Query: 634 QQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLY 693 +++ + E + S + ++++ E K EE+ + S+K + K + L Sbjct: 961 KKELESKESMNTNTSTI-NEEIDGEAKENDSEEE----NTSEKS------HHKKHHKDLI 1009 Query: 694 GTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGI 753 G + N K + + +L+ I+ ++ LT I LA+ E S +T + Sbjct: 1010 GKL----NQKNNEIKQLEKEIK-SLKLTLSERSNELNNIRRTLAE--KENNSNDET---L 1059 Query: 754 DAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAY 813 K++E IEN++ E+ ++K++ EE + + + L+ + ++L S Q++++ Sbjct: 1060 QKKVEE----IENLKKEIEEFKNKSSN-EEELNSLRESNQKLKEEIEKLNSKPQKEEENE 1114 Query: 814 SEYTIQEDELVNRLAVLMDHDRVVEKQLL-EIEHENKELQKKNQILLEENQNLQISLSDM 872 + + E H + K L+ ++ +N E+++ L +E + L+++LS+ Sbjct: 1115 EKDKENDSEEGEENTSEKSHHKKHHKDLIGKLNKKNNEIKQ----LEKEIKGLKLTLSEK 1170 Query: 873 QQHYN----ALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTL--IVQKKKEIE 926 N L EK N ++ + K ++ +L+ + +T ++ L ++ + K+ + Sbjct: 1171 SNELNNIRRTLAEKENNSN--DETLQKKVEEIENLKKEINSLTESNENLKNLIDEMKKKD 1228 Query: 927 DLEIEFNTQIESAIRDKKVLNEK---YEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNK 983 + T ++ KK ++EK ++ + V + L ++ N E +E + Sbjct: 1229 TTNNKSKTPVKFI---KKAMSEKELSFKPMAQTVRSRDLNLTDFSLNEEQFRQEMESWKR 1285 Query: 984 MNLELIDKHVQ-KQQTQSPDYTEQYINEINKLN----ALLKQKDEEIIALNQKINNAQVS 1038 + E ++ +QQ S D + + + K + + +E+ L Q Sbjct: 1286 IATERARENDDLRQQINSRDQEIEKLKKEEKSTNFQISKMNNDKQELAKLRQDNTYKDKE 1345 Query: 1039 YMSMVSDYESKLAQ---FTTKLENMEEEMQRVSKQLLDSKQHN-EELQILVREQDDQIKE 1094 ++S+ SK + T+L+ E ++ K L +SK+++ ++L+ + +D++I+ Sbjct: 1346 IQRLLSEASSKETENNKLKTELDQKNNECNKL-KTLNNSKENDIKQLKQDLSHKDNEIQA 1404 Query: 1095 LKETKLTFEMNI--PKTEGMIISST-----IEPMSDD----ANNVDXXXXXXXXXXXXLK 1143 LK + E I K EG++ S T + ++ D V K Sbjct: 1405 LKNEIHSKENEIIKVKNEGLMNSVTQLQRKVAALTTDKTMLTEEVKLHTSRLSVLAAERK 1464 Query: 1144 VQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSK- 1202 +EEEE + + L+ + + ELQE K QLE LN+ + N++ N+LK K Sbjct: 1465 SREEEEQLMAK--LKRRLIAKDVELQE---KDRQLEFLNSSVKKLKKENEQLNNELKEKN 1519 Query: 1203 --LEQLNTENDNLLSTVAELRSSISSAV 1228 L QL+ +++ + T+ +++ S + Sbjct: 1520 LRLSQLDNVHESAIRTMRRRQATKKSGI 1547 >UniRef50_Q23PQ6 Cluster: Putative uncharacterized protein; n=1; Tetrahymena thermophila SB210|Rep: Putative uncharacterized protein - Tetrahymena thermophila SB210 Length = 2269 Score = 142 bits (343), Expect = 9e-32 Identities = 226/1294 (17%), Positives = 545/1294 (42%), Gaps = 99/1294 (7%) Query: 337 QIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSG---RNTASKMKSPWSQLSSET 393 QI +TN+EL + + ++ ++ +++ +N + ++++ + S + Sbjct: 351 QIIRTNQELSEQFDNNSNFNTDLNERILDRKVILQKQNKLEKKNKSLRVENIELKNSLKV 410 Query: 394 LNQDTDKKINKNEIAKL--EMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQ 451 N +T K K E+ K +++ LN++ +K+ + D K I Q Sbjct: 411 FNNETSKLEKKLEVEKKNNKLLNDILNQEFSEKQLIAQLNDIIENQKQEISELKID-IEQ 469 Query: 452 LQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQ 511 LQ++ + I N++D +E+ +Q + D+ K +K +I+ S E+ Sbjct: 470 LQIKVDNSKQEFEYIKSNPNSQDFDEMENEYDQAEALKQDQWK---IK-IIQAKSSVLEE 525 Query: 512 ITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKV 571 Q+ + + + ++ ++ +Q Q + +++ + K + + ++ + K+ Sbjct: 526 KQQMESQKKDIEEKLRLIEEEKEVIYRQNQNYQNENTQLKNCYKTVEKQFKDAVKENDKL 585 Query: 572 AELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELH 631 + ++E Q L + + + + L E +L+ + L Q D+ Q+L Sbjct: 586 KKKQQEFEEKQKRLEELEQ-------------QSQQLQE-QLQELEELRKQNEDIQQQLI 631 Query: 632 ILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQ 691 ++ E+E +L+ + QL S+ ++ + +EE + L A K E L+ D ++ Sbjct: 632 SEKKSRLEIETQLSSLRQLDSNNPSAQ--NSFIEEDKEQLLAEK-------EKLEEDLKE 682 Query: 692 LYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQF 751 T ++E K + ++ Q+ + +L+K EK + N ++ Q Q Sbjct: 683 ALRTKSEIELQKASFQTENASFRQQYKKIEKQLKKSIKEKEALKKELENEKKLFAEQLQS 742 Query: 752 GIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQK 811 G I++ ++ + E +++ R +LE + ++ + ++E+ ++EK Sbjct: 743 GEAKVIEQLKQELKQTKEERDEFQKRSSKLENKLKSLQQEQ-NMEKMETDFDKQIEEKIN 801 Query: 812 AYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSD 871 A I+E + VL ++K+L E E +++K+Q +L ENQN Q +LS Sbjct: 802 AAKSQVIEEKQ------VLEAEKEDIQKKLEETNREKLLIERKSQAVLSENQNFQQTLSS 855 Query: 872 MQQHYN-ALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEI 930 +Q+ A+ E+ + + S K+ ++ +E + ++ + ++++E L Sbjct: 856 LQKELKVAIKERDSIKNEVTSLRNKFAKKVELIEKLKTKFGYQEEEDQEEEEQEDPKLMH 915 Query: 931 EFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYK--NNIENLNMNVEELNKMNLEL 988 + N ++ + L E+ E I+ + + ++++ E + ++++ L +E N EL Sbjct: 916 QHNREVRDLLTQIDQLKEEKEDLIQQIKEKQSKIDELQSDSSMQKLEEEYDEENSNKTEL 975 Query: 989 ---IDKHVQKQ---QTQSPDYTEQYINEINKLNALLKQKDE---EIIALNQKINNA---- 1035 ID V+++ + ++ Y + Y N + +KQ DE ++ QKI+ Sbjct: 976 QVQIDNLVKQKSRVEIENNYYKDTYKNVEKEFKKSVKQNDELKKKLAEAEQKISQLEKKV 1035 Query: 1036 ---------QVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVR 1086 + + S ++++ + +LE ++ E + + +L N++LQ + Sbjct: 1036 PKEDQEEGDEEEQQQIESSAQAEINELKQQLEKVKNENKNLKNELNSITDSNKDLQKAIE 1095 Query: 1087 E--QDDQIKELKE--TKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXL 1142 + ++ QIK L+ E + K + M I + + + + L Sbjct: 1096 DAREEQQIKRLENEYDNQPDEDKLEKAKSMFIQEKL-VLEIEKEEIANQLSQKLSELDSL 1154 Query: 1143 KVQEEEEFIQERSVLQ----------EQSAKLNTELQECYTKIIQLETLNTELTGHDVVN 1192 + + ++ + E + L+ +++ K N EL++ + K +ET N ++ + Sbjct: 1155 Q-KSSQQIVLENNGLKSTFKSFEKEFKRTVKENDELKKSFKK---METENQKIKDQVAMY 1210 Query: 1193 QEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQK 1252 ++Q+ + + E E+ + + + S+ DQ E+ + K +L +E + K Sbjct: 1211 KQQLGIVDTPTED-QEEDQSPVQNKHQQPLKQSNHSDQEFNELQD--KYNLMVKEFEEFK 1267 Query: 1253 TEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEK 1312 EHE+ Q+ F+ K L + Q E K + SL + ++ L+++ Sbjct: 1268 KEHEM--QIMEFQEKEVYLQKTKTEIEQIEWEKSDLERKANSLSQEQSTHKQFYVTLEKQ 1325 Query: 1313 YADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTEN--QSYKQMQEQSILNI 1370 + + +I+ LR + D+ V + L +N + K + ++ + Sbjct: 1326 FKKSVKEIDNLRKD-NDKLVKYKERLSELVSQVIKKQEPLDEQNGDEEDKLLTVNPLVEL 1384 Query: 1371 NEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQR 1430 + A L++ + + N ++ + + SE+ ++ Sbjct: 1385 TRQKAMLEQKNSYLTEQLEEMSKQNNQPSPAYVQQNNDNGAEVSELTEQLQNEQNENKSL 1444 Query: 1431 NDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEE 1490 + + Q + + +D E E++L ++LK+ E +K+ E + +++ Sbjct: 1445 KAQIRTIEDQYQQKDSEQKDKIAELETQLQEIKLKLQEKDQKVNEKEKKLN-ELLGQLDQ 1503 Query: 1491 LNVKITESVSLNKQVAELNKALEEEVAKTNEMQ-----TALENQEIE-IVTLNDEITNLQ 1544 N +I + + +Q + NK L ++ + E+Q L+N+ +E N+ + N Sbjct: 1504 QNQEIKKQYTFIQQSQQNNKELAKKNQEIEELQLQVKDLILDNKIVEQYKQQNEMLKNKC 1563 Query: 1545 NMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNK 1578 ++ +S ++IQ+ + + + ++ +++ +N+ Sbjct: 1564 EILESSLTEIQEKKNQLINKIKDKESKIEVELNQ 1597 Score = 128 bits (310), Expect = 9e-28 Identities = 222/1103 (20%), Positives = 474/1103 (42%), Gaps = 102/1103 (9%) Query: 490 NDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIK-VKSNHKL----KLKQMQKTI 544 +DEI D EK + EEQI QL +E NM K +K ++ L L+Q Q + Sbjct: 286 SDEILSSKSLDDDEKKYNLEEQIEQLKEE------NMFKQIKIDNLLVQLGALEQKQSSF 339 Query: 545 DNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIE 604 D D +I+R +EL +E + N L + R+++ K +++ Sbjct: 340 DYQDAKIDELMQIIRTNQEL-------SEQFDNNSNFNTDL----NERILDR---KVILQ 385 Query: 605 MENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKL---ADISQLQSDQVCSEIKS 661 +N E + K+ L + +L L + + ++E KL ++L +D + E Sbjct: 386 KQNKLEKKNKS---LRVENIELKNSLKVFNNETSKLEKKLEVEKKNNKLLNDILNQEFSE 442 Query: 662 VHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLT 721 L Q++ + ++K+ I LK+D EQL IK ++N K++ YI+ N + Sbjct: 443 KQLIAQLNDIIENQKQ---EISELKIDIEQL--QIK-VDNSKQEF-----EYIKSNPNSQ 491 Query: 722 DKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRL 781 D ++M E A+ ++Q KI+ + ++E+ + +ES+ + ++ + Sbjct: 492 D-FDEMENEYDQ---AEALKQDQWKIKIIQAKSSVLEEK----QQMESQKKDIEEKLRLI 543 Query: 782 EESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQL 841 EE V+ + + + + QL + + +K + + + D+L + + +K+L Sbjct: 544 EEEKEVIYRQNQNYQNENTQLKNCYKTVEKQFKDAVKENDKLKKKQQEFEEK----QKRL 599 Query: 842 LEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLR 901 E+E ++++LQ++ L+E + L+ D+QQ + EK +R ++ S+ Q Sbjct: 600 EELEQQSQQLQEQ----LQELEELRKQNEDIQQ--QLISEKKSRLEIETQLSSLRQLDSN 653 Query: 902 DLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLE 961 + + I + + L+ +K+K EDL+ T+ E ++ E +Y ++E Sbjct: 654 NPSAQNSFIEEDKEQLLAEKEKLEEDLKEALRTKSEIELQKASFQTENASFRQQY-KKIE 712 Query: 962 AQLQEYKNNIENLNMNVEELNKMNLELI---DKHVQKQQTQSPDYTEQYINEINKLNALL 1018 QL++ E L +E K+ E + + V +Q Q T++ +E K ++ L Sbjct: 713 KQLKKSIKEKEALKKELENEKKLFAEQLQSGEAKVIEQLKQELKQTKEERDEFQKRSSKL 772 Query: 1019 KQKDEEIIALNQKINNAQVSYMSMVSD-YESKLAQFTTKLENMEEEMQRVSKQLLDSKQH 1077 + K + + Q + + + + + + +Q + + +E E + + K+L ++ Sbjct: 773 ENKLKS-LQQEQNMEKMETDFDKQIEEKINAAKSQVIEEKQVLEAEKEDIQKKL---EET 828 Query: 1078 NEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXX 1137 N E ++ R+ + E + + T ++ K + I + + ++ ++ Sbjct: 829 NREKLLIERKSQAVLSENQNFQQTLS-SLQKELKVAIKER-DSIKNEVTSLRNKFAKKVE 886 Query: 1138 XXXXLKV----QEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQ 1193 LK QEEE+ +E + + N E+++ T+I QL+ +L Q Sbjct: 887 LIEKLKTKFGYQEEEDQEEEEQEDPKLMHQHNREVRDLLTQIDQLKEEKEDLIQQIKEKQ 946 Query: 1194 EQINQLK--SKLEQLNTENDNLLSTVAELRSSISSAVDQRG-FEIA-ELWKQHLAQREAD 1249 +I++L+ S +++L E D S EL+ I + V Q+ EI +K E + Sbjct: 947 SKIDELQSDSSMQKLEEEYDEENSNKTELQVQIDNLVKQKSRVEIENNYYKDTYKNVEKE 1006 Query: 1250 FQKT---EHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHL 1306 F+K+ EL+ +L+ E K QL V QEE ++ + +S Q ++ + ++ L Sbjct: 1007 FKKSVKQNDELKKKLAEAEQKISQLEKKVPKEDQEEGDEEEQQQIESSAQAEINELKQQL 1066 Query: 1307 RNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQ----- 1361 ++ + ++ N++ + +D + A D + + ++ Sbjct: 1067 EKVKNENKNLKNELNSITDSNKDLQKAIEDAREEQQIKRLENEYDNQPDEDKLEKAKSMF 1126 Query: 1362 MQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQ-LELKDSEIYQKT 1420 +QE+ +L I +E + S + E L+ T + E + ++ Sbjct: 1127 IQEKLVLEIEKEEIANQLSQKLSELDSLQKSSQQIVLENNGLKSTFKSFEKEFKRTVKEN 1186 Query: 1421 HEYTITLTQRNDEFENVRQQLVEYEKR---IEDLTYEKESELAILRLKMHENANHYETMQ 1477 E + + E + ++ Q+ Y+++ ++ T ++E + + ++ K H + ++ Sbjct: 1187 DELKKSFKKMETENQKIKDQVAMYKQQLGIVDTPTEDQEEDQSPVQNK------HQQPLK 1240 Query: 1478 KESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLN 1537 + + ++ EL K V K+ E K E ++ + E + L+ + EI + Sbjct: 1241 QSNHSDQE--FNELQDKYNLMV---KEFEEFKKEHEMQIMEFQEKEVYLQKTKTEIEQIE 1295 Query: 1538 DEITNLQNMVRASSSKIQKHVSF 1560 E ++L+ + S + H F Sbjct: 1296 WEKSDLERKANSLSQEQSTHKQF 1318 Score = 128 bits (309), Expect = 1e-27 Identities = 228/1161 (19%), Positives = 495/1161 (42%), Gaps = 94/1161 (8%) Query: 212 EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271 E KQ K++ I ++ +EKQ++ + + ++ +EE +++ E+ Sbjct: 504 EALKQDQWKIK--IIQAKSSVLEEKQQMESQKKDIEEKLRLIEEEKEVIYRQNQNYQNEN 561 Query: 272 SKLAQELEQXXXXXXXXXXXXXXLAK--QSIEPSCEEKTEIEEKGSL---EIANMTELTK 326 ++L + L K Q E + E+E++ ++ + EL K Sbjct: 562 TQLKNCYKTVEKQFKDAVKENDKLKKKQQEFEEKQKRLEELEQQSQQLQEQLQELEELRK 621 Query: 327 KIELLEHLNCQIRQTNKELENKLATMGT-ESKAVSSPSK-----KGSPLISRKSGRNTAS 380 + E ++ +++ E+E +L+++ +S S+ + K L ++ Sbjct: 622 QNEDIQQQLISEKKSRLEIETQLSSLRQLDSNNPSAQNSFIEEDKEQLLAEKEKLEEDLK 681 Query: 381 KMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISE-KDTXXXXXX 439 + S++ + + T+ + + K+E + L K + +KE + E ++ Sbjct: 682 EALRTKSEIELQKASFQTENASFRQQYKKIE---KQLKKSIKEKEALKKELENEKKLFAE 738 Query: 440 XXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVK 499 G+ +I QL+ E +Q E ++ + N++ +Q++ E + D K Sbjct: 739 QLQSGEAKVIEQLKQELKQTKEERDEFQKRSSKLE-NKLKSLQQEQNMEKMETDFD---K 794 Query: 500 DLIEKLKSAEEQITQLNDEIDAANKNMIK-VKSNHKLKLKQMQKTIDNFSKVSDSNKEIV 558 + EK+ +A+ Q+ + ++A +++ K ++ ++ KL +K+ S+ + + + Sbjct: 795 QIEEKINAAKSQVIEEKQVLEAEKEDIQKKLEETNREKLLIERKSQAVLSENQNFQQTLS 854 Query: 559 RLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYK-KMIEMENLAETRLKAIS 617 L +EL ++ ++ E +L+ +IE K E E+ E + Sbjct: 855 SLQKELKVAIKERDSIKNEVTSLRNKFAK--KVELIEKLKTKFGYQEEEDQEEEEQEDPK 912 Query: 618 LLESQKFDLVQELHILQQKYDEVEDKLADISQLQS--DQVCSEIKSVHLEEQIDALSASK 675 L+ ++ L + Q +E ED + I + QS D++ S+ LEE+ D +++K Sbjct: 913 LMHQHNREVRDLLTQIDQLKEEKEDLIQQIKEKQSKIDELQSDSSMQKLEEEYDEENSNK 972 Query: 676 KELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISEL 735 EL + I+NL K ++ ++ +++ + + +++N +L KL + + +KIS+L Sbjct: 973 TELQVQIDNLVKQKSRVEIENNYYKDTYKNVEKEFKKSVKQNDELKKKLAE-AEQKISQL 1031 Query: 736 LAKINHEEQSK--IQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRY 793 K+ E+Q + + Q I++ Q I ++ +L K K+ L+ + + D Sbjct: 1032 EKKVPKEDQEEGDEEEQQQIESSAQAE---INELKQQLEKVKNENKNLKNELNSITDSNK 1088 Query: 794 SLERKADQLGSYLQEKQKAYSEYTIQ--EDELVNRLAVLMDHDRVVEKQLLEIEHENKE- 850 L+ KA + Q+ ++ +EY Q ED+L ++ + V+E + EI ++ + Sbjct: 1089 DLQ-KAIEDAREEQQIKRLENEYDNQPDEDKLEKAKSMFIQEKLVLEIEKEEIANQLSQK 1147 Query: 851 ------LQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLA----ESESTK----- 895 LQK +Q ++ EN L+ + ++ + V++ + + E+E+ K Sbjct: 1148 LSELDSLQKSSQQIVLENNGLKSTFKSFEKEFKRTVKENDELKKSFKKMETENQKIKDQV 1207 Query: 896 --YQTQL-------RDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVL 946 Y+ QL D E + + ++HQ + Q ++ E + +++ + Sbjct: 1208 AMYKQQLGIVDTPTEDQEEDQSPVQNKHQQPLKQSNHSDQEFN-ELQDKYNLMVKEFEEF 1266 Query: 947 NEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDK---HVQKQQTQSPDY 1003 +++E I + E LQ+ K IE + +L + L + H Q T + Sbjct: 1267 KKEHEMQIMEFQEKEVYLQKTKTEIEQIEWEKSDLERKANSLSQEQSTHKQFYVTLEKQF 1326 Query: 1004 TEQY--INEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKL------AQFTT 1055 + I+ + K N L + E + L ++ Q D E KL + T Sbjct: 1327 KKSVKEIDNLRKDNDKLVKYKERLSELVSQVIKKQEPLDEQNGDEEDKLLTVNPLVELTR 1386 Query: 1056 KLENMEEEMQRVSKQLLD-SKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMII 1114 + +E++ +++QL + SKQ+N+ V++ +D E+ E LT ++ + E + Sbjct: 1387 QKAMLEQKNSYLTEQLEEMSKQNNQPSPAYVQQNNDNGAEVSE--LTEQLQNEQNENKSL 1444 Query: 1115 SSTIEPMSDDANNVDXXXXXXXXXXXX------LKVQEEEEFIQERSV-LQEQSAKL--- 1164 + I + D D LK+QE+++ + E+ L E +L Sbjct: 1445 KAQIRTIEDQYQQKDSEQKDKIAELETQLQEIKLKLQEKDQKVNEKEKKLNELLGQLDQQ 1504 Query: 1165 NTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSI 1224 N E+++ YT I Q + N EL NQE I +L+ +++ L +N ++ + + Sbjct: 1505 NQEIKKQYTFIQQSQQNNKELAKK---NQE-IEELQLQVKDLILDN-KIVEQYKQQNEML 1559 Query: 1225 SSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETN 1284 + + + E+ ++ Q + E ++ V+L+ + QL + ++ + Sbjct: 1560 KNKCEILESSLTEI-QEKKNQLINKIKDKESKIEVELNQIKQVNHQLAQQNEMLKKDRIS 1618 Query: 1285 KIVTMEQVTSLQNKLQDKEEH 1305 +V +EQ LQN D +H Sbjct: 1619 MLVELEQAIQLQN--VDNRQH 1637 Score = 108 bits (259), Expect = 1e-21 Identities = 272/1287 (21%), Positives = 539/1287 (41%), Gaps = 175/1287 (13%) Query: 140 QLGDVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXX 199 Q D ++ +K+K Q +++ +E LQE++ E ++ + +N+ Sbjct: 574 QFKDAVKENDKLKKKQQEFEEKQKRLEELEQQSQQLQEQLQELEE-LRKQNEDIQQQLIS 632 Query: 200 XXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKL 259 +Q + N A + +++K++LL + E + + Sbjct: 633 EKKSRLEIETQLSSLRQLDS---NNPSAQNSFIEEDKEQLLAEKEKLEEDLKEALRTKSE 689 Query: 260 LEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIA 319 +E + E++ Q+ ++ L K E E+K E+ S E Sbjct: 690 IELQKASFQTENASFRQQYKKIEKQLKKSIKEKEALKK---ELENEKKLFAEQLQSGEAK 746 Query: 320 NMTELTKKIELLEHLNCQIRQTNKELENKLATMGTE---SKAVSSPSKKGSPLISRKSGR 376 + +L ++++ + + ++ + +LENKL ++ E K + K+ I+ + Sbjct: 747 VIEQLKQELKQTKEERDEFQKRSSKLENKLKSLQQEQNMEKMETDFDKQIEEKINAAKSQ 806 Query: 377 NTASK---------MKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYV 427 K ++ + + E L + + +E + + SL K+L + Sbjct: 807 VIEEKQVLEAEKEDIQKKLEETNREKLLIERKSQAVLSENQNFQQTLSSLQKEL---KVA 863 Query: 428 ISEKDT---XXXXXXXXXXGKDTLIAQLQL---------EHQQHMEGPSLIHVGTNTEDV 475 I E+D+ K LI +L+ + ++ E P L+H + +V Sbjct: 864 IKERDSIKNEVTSLRNKFAKKVELIEKLKTKFGYQEEEDQEEEEQEDPKLMH--QHNREV 921 Query: 476 NEIAKVQEQLKQELNDEIKDVNVK-DLIEKLKSAEEQITQLNDEIDA--ANKNMIKVKSN 532 ++ +QLK+E D I+ + K I++L+S + + +L +E D +NK ++V+ + Sbjct: 922 RDLLTQIDQLKEEKEDLIQQIKEKQSKIDELQS-DSSMQKLEEEYDEENSNKTELQVQID 980 Query: 533 HKLKLKQMQKTIDNFSKVSDSN--KEIVRLTEELHHLSQKVAELEEEKGNLQLHLV---- 586 + +K K + +N+ K + N KE + ++ L +K+AE E++ L+ + Sbjct: 981 NLVKQKSRVEIENNYYKDTYKNVEKEFKKSVKQNDELKKKLAEAEQKISQLEKKVPKEDQ 1040 Query: 587 ---DYDSGRMIESDVYKKMIEMENLAE--------TRLKAISLLESQKFDL--------- 626 D + + IES ++ E++ E + + S+ +S K DL Sbjct: 1041 EEGDEEEQQQIESSAQAEINELKQQLEKVKNENKNLKNELNSITDSNK-DLQKAIEDARE 1099 Query: 627 VQELHILQQKYDEV--EDKLADI-SQLQSDQVCSEIKSVHLEEQ-------IDALSASKK 676 Q++ L+ +YD EDKL S +++ EI+ + Q +D+L S + Sbjct: 1100 EQQIKRLENEYDNQPDEDKLEKAKSMFIQEKLVLEIEKEEIANQLSQKLSELDSLQKSSQ 1159 Query: 677 ELALVIENLK-----LDKE---------QLYGTIKDLENDKEDIMNKLQNYIQE----NM 718 ++ L LK +KE +L + K +E + + I +++ Y Q+ + Sbjct: 1160 QIVLENNGLKSTFKSFEKEFKRTVKENDELKKSFKKMETENQKIKDQVAMYKQQLGIVDT 1219 Query: 719 DLTDKLEKMS--AEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKS 776 D+ E S K + L + NH +Q + Q + ++E + + + E ++ +++ Sbjct: 1220 PTEDQEEDQSPVQNKHQQPLKQSNHSDQEFNELQDKYNLMVKEFEEFKKEHEMQIMEFQE 1279 Query: 777 RICRLEES---IAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVL-MD 832 + L+++ I +E + LERKA+ L ++ Y Q + V + L D Sbjct: 1280 KEVYLQKTKTEIEQIEWEKSDLERKANSLSQEQSTHKQFYVTLEKQFKKSVKEIDNLRKD 1339 Query: 833 HDRVV--EKQLLEI----------------EHENK--------ELQKKNQILLEENQNLQ 866 +D++V +++L E+ + E+K EL ++ +L ++N L Sbjct: 1340 NDKLVKYKERLSELVSQVIKKQEPLDEQNGDEEDKLLTVNPLVELTRQKAMLEQKNSYLT 1399 Query: 867 ISLSDMQQHYN----ALVEKANRTDLAESESTKY----QTQLRDLESNLKRITHEHQTLI 918 L +M + N A V++ N SE T+ Q + + L++ ++ I ++Q Sbjct: 1400 EQLEEMSKQNNQPSPAYVQQNNDNGAEVSELTEQLQNEQNENKSLKAQIRTIEDQYQQKD 1459 Query: 919 VQKKKEIEDLEIEF-NTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNN---IENL 974 ++K +I +LE + +++ +D+KV NEK +K E + QL+ Q QE K I+ Sbjct: 1460 SEQKDKIAELETQLQEIKLKLQEKDQKV-NEKEKKLNELLGQLDQQNQEIKKQYTFIQQS 1518 Query: 975 NMNVEELNKMNLELIDKHVQ-KQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKIN 1033 N +EL K N E+ + +Q K EQY + N +LK K E + + +I Sbjct: 1519 QQNNKELAKKNQEIEELQLQVKDLILDNKIVEQY----KQQNEMLKNKCEILESSLTEIQ 1574 Query: 1034 NAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIK 1093 + ++ + D ES K+E ++++V+ QL + ++ +I + + +Q Sbjct: 1575 EKKNQLINKIKDKES-------KIEVELNQIKQVNHQLAQQNEMLKKDRISMLVELEQAI 1627 Query: 1094 ELKETKLTFEMNIPKTEGMIIS--STIEPMS-DDANNVDXXXXXXXXXXXXLKVQEEEEF 1150 +L+ NIP + S + P S D N + KV EE + Sbjct: 1628 QLQNVDNRQHFNIPTSGSKFTSPNNLKNPKSLTDIQNDNQAKIQDKIHEYQQKVY-EEVY 1686 Query: 1151 IQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQ-EQINQLKSK--LE-QL 1206 Q+ L E + L +E + Y K +L L E HD + +QI + K L+ +L Sbjct: 1687 NQQDDDLNE-NYPLPSEGSDGYGK--KLSKLEDEF--HDQIQALKQIIKSKEHEILQLKL 1741 Query: 1207 NTENDNLLSTVAELRSSISSAVDQR--GFEIAELWKQHLAQREADFQKTEHELRVQLSAF 1264 N E +NL T + + IS QR GF+IA Q + D + H + Sbjct: 1742 NKEENNLEITPRD-KKVISDISPQRKTGFKIATGSNQQITDYATDRRTKNHSANM----- 1795 Query: 1265 ESKYEQLLDSVQSSTQEETNKIVTMEQ 1291 Y Q + S+Q++ + +K++ Q Sbjct: 1796 --LYYQSIQSIQNNQGDSQSKLLGSTQ 1820 Score = 87.8 bits (208), Expect = 2e-15 Identities = 153/806 (18%), Positives = 350/806 (43%), Gaps = 66/806 (8%) Query: 806 LQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNL 865 L+EKQ + TI++D + D ++ + L+ + + L+++ + L EEN Sbjct: 263 LKEKQFETLKQTIEQDNKSDGSR----SDEILSSKSLDDDEKKYNLEEQIEQLKEENMFK 318 Query: 866 QISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEI 925 QI + ++ AL +K + D YQ D L +I +Q L E Sbjct: 319 QIKIDNLLVQLGALEQKQSSFD--------YQDAKID---ELMQIIRTNQEL-----SEQ 362 Query: 926 EDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMN 985 D FNT + I D+KV+ +K K + L + E KN+++ N +L K Sbjct: 363 FDNNSNFNTDLNERILDRKVILQKQNKLEKKNKSLRVENIELKNSLKVFNNETSKLEK-K 421 Query: 986 LELIDKHVQ-KQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVS 1044 LE+ K+ + + +++E+ + I +LN +++ + +EI L I Q+ + Sbjct: 422 LEVEKKNNKLLNDILNQEFSEKQL--IAQLNDIIENQKQEISELKIDIEQLQIKVDNSKQ 479 Query: 1045 DYE----SKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQ--DDQIKELKE- 1097 ++E + +Q ++EN ++ + + + K + +L +Q + Q K+++E Sbjct: 480 EFEYIKSNPNSQDFDEMENEYDQAEALKQDQWKIKIIQAKSSVLEEKQQMESQKKDIEEK 539 Query: 1098 -TKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSV 1156 + E + + + + + V+ LK ++++EF +++ Sbjct: 540 LRLIEEEKEVIYRQNQNYQNENTQLKNCYKTVEKQFKDAVKENDKLK-KKQQEFEEKQKR 598 Query: 1157 LQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLST 1216 L+E L + Q+ ++ +LE L + ++ + Q+ I++ KS+LE + T+ +L Sbjct: 599 LEE----LEQQSQQLQEQLQELEELRKQ---NEDIQQQLISEKKSRLE-IETQLSSLRQL 650 Query: 1217 VAELRSSISSAVDQRGFE-IAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSV 1275 + S+ +S +++ + +AE K+ L + + +T+ E+ +Q ++F+++ Sbjct: 651 DSNNPSAQNSFIEEDKEQLLAE--KEKLEEDLKEALRTKSEIELQKASFQTENASFRQQY 708 Query: 1276 QSSTQEETNKIVTMEQVTSLQNKLQ-DKEEHLRNLQEKYADVINQIEILRSEIEDEKVAF 1334 + +++ K ++++ +L+ +L+ +K+ LQ A VI Q++ + ++E+ F Sbjct: 709 K-KIEKQLKK--SIKEKEALKKELENEKKLFAEQLQSGEAKVIEQLKQELKQTKEERDEF 765 Query: 1335 XXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXR 1394 + E +Q IN +Q+ + + Sbjct: 766 QKRSSKLENKLKSLQQEQNMEKME-TDFDKQIEEKINAAKSQVIEEKQVLEAEKEDIQKK 824 Query: 1395 VNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYE 1454 + + + L +E K + + + TL+ E + ++ + + L + Sbjct: 825 LEETNREKL----LIERKSQAVLSENQNFQQTLSSLQKELKVAIKERDSIKNEVTSLRNK 880 Query: 1455 KESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKI----TESVSLNKQVAELNK 1510 ++ ++ + E Q+E E E KL+ + N ++ T+ L ++ +L + Sbjct: 881 FAKKVELIEKLKTKFGYQEEEDQEEEEQEDPKLMHQHNREVRDLLTQIDQLKEEKEDLIQ 940 Query: 1511 ALEEEVAKTNEMQ--TALENQEIEIVTLNDEITNLQ----NMVRASSSKIQKHVSFASDT 1564 ++E+ +K +E+Q ++++ E E N T LQ N+V+ S+++ ++ DT Sbjct: 941 QIKEKQSKIDELQSDSSMQKLEEEYDEENSNKTELQVQIDNLVK-QKSRVEIENNYYKDT 999 Query: 1565 KQGRDEQLDNTM--NKELLDAVPRAE 1588 + +++ ++ N EL + AE Sbjct: 1000 YKNVEKEFKKSVKQNDELKKKLAEAE 1025 Score = 69.3 bits (162), Expect = 8e-10 Identities = 126/677 (18%), Positives = 281/677 (41%), Gaps = 42/677 (6%) Query: 860 EENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIV 919 EE+ N I + + + + ++ + + + K Q Q E L++I +E L++ Sbjct: 93 EESDNEDIDSKNNGKQEKSRTQNTSKYNSKKIDELKKQLQNAKNELQLQKIKYE---LMI 149 Query: 920 QKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIE-YVTQLEAQLQEYKNNIENLNMNV 978 K E ++ +TQ E I+D ++L+E++ + Y+ Q + + +KN L + Sbjct: 150 LKFNEFITHQVFCHTQCEQNIKDDELLSEQFNILLNTYLCQKDDYAKYFKNQSWTLQGSA 209 Query: 979 EELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVS 1038 + L L+ ++ Q+ Q+ + N I K +L+++ + I+ IN +++ Sbjct: 210 QSLPTSPLK--NQSPQESFLQAEFLVD---NTIKKFYQILEKETSDPISYRNHIN--EIT 262 Query: 1039 YMSMVSDYESKLAQFTTKLENMEEEMQRVSKQL-LDSKQHNEELQILVREQDDQIKELKE 1097 + + + K + + SK L D K++N E QI ++++ K++K Sbjct: 263 LKEKQFETLKQTIEQDNKSDGSRSDEILSSKSLDDDEKKYNLEEQIEQLKEENMFKQIKI 322 Query: 1098 TKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEE-EEFIQERSV 1156 L ++ + + + + + + E I +R V Sbjct: 323 DNLLVQLGALEQKQSSFDYQDAKIDELMQIIRTNQELSEQFDNNSNFNTDLNERILDRKV 382 Query: 1157 LQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLST 1216 + ++ KL E K +++E N EL V + ++L+ KLE + +N+ LL+ Sbjct: 383 ILQKQNKL-----EKKNKSLRVE--NIELKNSLKVFNNETSKLEKKLE-VEKKNNKLLND 434 Query: 1217 VAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQ 1276 + S + Q +I E KQ +++ + D + +L++++ + ++E + + Sbjct: 435 ILNQEFSEKQLIAQLN-DIIENQKQEISELKIDIE----QLQIKVDNSKQEFEYIKSNPN 489 Query: 1277 SSTQEE-TNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFX 1335 S +E N+ E + Q K++ + L+EK Q+E + +IE EK+ Sbjct: 490 SQDFDEMENEYDQAEALKQDQWKIKIIQAKSSVLEEK-----QQMESQKKDIE-EKLRLI 543 Query: 1336 XXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRV 1395 + T+ ++ + E+ + +EN +LKK Sbjct: 544 EEEKEVIYRQNQNYQNENTQLKNCYKTVEKQFKDAVKENDKLKKKQQEFEEKQKRLEELE 603 Query: 1396 NDAE--AKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTY 1453 ++ + L+ +L ++ +I Q+ + + + ++RQ Sbjct: 604 QQSQQLQEQLQELEELRKQNEDIQQQLISEKKSRLEIETQLSSLRQLDSNNPSAQNSFIE 663 Query: 1454 EKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALE 1513 E + +L + K+ E+ E ++ +SEIE K + TE+ S +Q ++ K L+ Sbjct: 664 EDKEQLLAEKEKLEEDLK--EALRTKSEIELQKASFQ-----TENASFRQQYKKIEKQLK 716 Query: 1514 EEVAKTNEMQTALENQE 1530 + + + ++ LEN++ Sbjct: 717 KSIKEKEALKKELENEK 733 >UniRef50_A0CPT0 Cluster: Chromosome undetermined scaffold_23, whole genome shotgun sequence; n=2; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_23, whole genome shotgun sequence - Paramecium tetraurelia Length = 2301 Score = 142 bits (343), Expect = 9e-32 Identities = 327/1612 (20%), Positives = 659/1612 (40%), Gaps = 140/1612 (8%) Query: 90 ISESLANTLKQKEILMEKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLG------- 142 +S ++ +KQ + ++IKQ +E S + S + + ++ Sbjct: 217 LSYNIKEIIKQNSNVQKEIKQKEEESTKQSNKLEKYKKQIEQKNSQIDSLKMDVKNLNQQ 276 Query: 143 -----DVTHLSNTIKEKDNALSVLQVKM----KIM---ETTILDLQEKINEKDQIIEAKN 190 + L++ IK++ + +LQ ++ KI+ ET I QEK N+ Q I+ Sbjct: 277 LQNQETINSLNDCIKKQSQQIDILQQQIIEQNKILEQNETIIAKQQEKENQLFQEIKMIK 336 Query: 191 KATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRL-LKDIESKDVR 249 D +Q++ ++ M E +Q+ ++IE K + Sbjct: 337 CEKVKSLQQDEDDQIKYKNTINDLRQEINELNAQLENMYTEQAQLQQQFDEQEIEHKKSQ 396 Query: 250 ISSLEEANKL-LEAARFEISLEHSKLA--QELEQXXXXXXXXXXXXXXLAKQSIEPSCEE 306 I K LE +++ +E +K+ Q+L+Q + SI+ E Sbjct: 397 IQMTNTIQKFQLEVKKYQQLVEDNKIQFNQQLKQQQQQHKQIQQELIN-NQNSIQNQLSE 455 Query: 307 KTEIEEKGSLEIANMTELTKKIE-LLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKK 365 +I E + + L + +E L+++LN I+Q K L+N +T S + SK Sbjct: 456 YLQIIE----NLKSKENLNQVLENLIDNLNLVIKQ--KLLQNLKSTSSLASSPMRGMSKN 509 Query: 366 GSPL--ISRKSGRN--TASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDL 421 SP+ I + N K+ S +S + LN+ + I K+E K + +IQ + + Sbjct: 510 SSPVRQILNHNNNNQIDLQKIHSTLDNISEQFLNR-LNLLIKKDE--KNQELIQHYCQQI 566 Query: 422 VDKEYVISE--KDTXXXXXXXXXXGKDTLIAQL-QLEHQQHM--EGPSLIH-VGTNTEDV 475 + + I + D K I ++ L+ ++ E S I + N + Sbjct: 567 EESQQTIQQLCDDNDQQKQFITQMCKILNIEKIDDLKERKSFSKEDQSYIETLNQNNAQI 626 Query: 476 NEIAKVQEQLKQELNDE---IKDVNV-----KDLIEKLKSAEEQ----ITQLNDEIDAAN 523 ++ ++L+Q++ + IKD + K+ I+ L +E TQ+ ++ Sbjct: 627 QQLISYNQELQQDIQQQQIIIKDYEIQIDHLKNQIKYLSQEKEDQCKFTTQIASPTQSSR 686 Query: 524 K-NMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQ 582 K ++IK+ N +++ + Q + N K+S + EI L +L + V EE +L Sbjct: 687 KDSIIKILQNEEIQNRDQQISELN-DKISILDIEISNLQHQLESQIKLVQSRNEEIQHLN 745 Query: 583 LHLVDYDSGRMIESDVYKKMIEMENLAETRLKA-ISLLESQKFDLVQELHILQQKYDEVE 641 + D + + ++ ++ + + I LE +D+ Sbjct: 746 SQVRDLLEKQQYFEQLINELNAYHQQSKNQQEVQIIKLEGVSYDISHNSFNFDALRTPTN 805 Query: 642 DK--LADISQLQS-DQVCSEIKSVHLEEQI-DALSASKKELALVIENLKLDKEQLYGTIK 697 + +I Q QS + S I + QI + +K++ +I+ +L +E+ K Sbjct: 806 QNYIIDEIQQEQSINSSLSSIVQMSPNTQIKQIIQLNKQQEENIIQKNRLIQEKEVDLEK 865 Query: 698 DLE--NDKEDIMNKLQNYIQE-NMDLTDKLEKMSAEKISELLAKINHEEQSK---IQTQF 751 E + I K + I E N+ LT EK+ + + + ++E +K I+ Q Sbjct: 866 QNEELQQLQSINAKNEQEINELNLQLTQLHEKIETLREEQTQIQQQNDEYTKKLVIEKQS 925 Query: 752 GIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSL---ERKADQLGSYLQE 808 ID +I+ I+ ++S + ++I L + ++ + +L E+ Q +Q Sbjct: 926 AID-QIELYKKEIQQVKSINDQLSTQIAELRIQLQTNQEEQITLTENEQIIQQQNKEIQF 984 Query: 809 KQKAYSEYTI---QEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNL 865 + +E I Q+D + L DH + K L I N +++ I EE Q + Sbjct: 985 LKTINNEKQIQISQQDYQLQNLKEQFDHLKSKSKNL--IIKTNSAIKEIKIIHAEELQQI 1042 Query: 866 QISLSDMQQ--HYNALVEKANRTDLAESESTK-YQTQLRDLESNLKRIT-HEHQTLIVQK 921 +++L QQ Y+ + + +S +K Y Q++ LES + E L+ Q Sbjct: 1043 KVNLLQEQQLLKYDMKQLETKFVAIEQSYQSKIYNAQVKILESEQSIVQFQEELKLLQQS 1102 Query: 922 KKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEEL 981 K +IE+ + + + N K + + Q E QLQ + I+ + ++E+ Sbjct: 1103 KLQIEEKYCKAQDEFLEQSQFIDQQNTKLKSQKSQLEQKEKQLQCIEIQIQEQSDHIEQS 1162 Query: 982 NKMNLELIDKHVQKQQTQSPDYTEQ-YINEINKLNA----LLKQKDEEIIALNQKINNAQ 1036 N+ L + Q QQ S E+ I+++N+ N+ LL+QK++++ L+ ++ N Q Sbjct: 1163 NQTTKTLQLEINQLQQILSQQLQEKNLIHDLNQQNSEKQQLLQQKEQQLKVLHSELENLQ 1222 Query: 1037 VSYMSMVSDYESKLAQFTTK-------LENMEEEMQRVSKQLLDSKQHNEELQILVREQD 1089 + +V + K K LE E ++ V++ L +KQ + L+ + + Sbjct: 1223 LQLDGIVQNQREKEQNLNVKILDQQSQLEQYESRLKEVTQTLQHNKQEFQNRINLIEQVN 1282 Query: 1090 DQIKELKETKLT----FEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQ 1145 + E + + E+N I+ E + + K+Q Sbjct: 1283 QDLNEKNQNNIVQIQKLEINEELMNKKILELEFELAKIRNESQEKARELSLINQDYHKLQ 1342 Query: 1146 EE-EEFIQERSVLQEQSAKLNTEL----QECYTKIIQLETLNTELTGHDVVNQEQINQLK 1200 ++ ++ IQ+ L +Q+ K ++ Q TK QL LN +L NQ+ +Q Sbjct: 1343 DDLKKEIQKAQNLIDQNIKYEQDIIQLKQNLTTKDQQLVGLNEQLNVSIKQNQDIQSQYT 1402 Query: 1201 SKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEI-AELWKQHLAQREADFQKTE----H 1255 K+ QL + NL L S + ++ + +L KQ+L + + + ++ Sbjct: 1403 LKVTQLEKQIINLEREKLLLNESNDQLIREKQNNLQQQLTKQNLNEEKENATSSQEVKIQ 1462 Query: 1256 ELRVQLSAFESKYEQLLDSVQSSTQEETN-KIVTMEQVTS--------LQNKLQDKEEHL 1306 +L+ QL + +QL DS Q Q+ N K ++Q+TS L Q EHL Sbjct: 1463 QLKDQLQKEQENIKQLQDSHQKQIQQYFNEKSQQIQQLTSNNDNLTLQLNESKQISNEHL 1522 Query: 1307 RNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQS 1366 N +K +IN + E + + L + + EQ+ Sbjct: 1523 -NDNDKLKSIINNQLTQIKQFEQAIIQYKNQLQDVKSQNENLVTILHQSENKWTNLNEQN 1581 Query: 1367 I---LNINEENAQLKKSSXXXXXXXXXXXXRV---NDAEAKVLELTHQL--ELKDSEIYQ 1418 L+I ++ Q+++ S ++ D E K+ E+ +QL E + SE Sbjct: 1582 TQYKLSIQQQEHQIQQQSLLILTQEEALKKQIIINVDQEKKLFEINNQLWQEQQVSEDLN 1641 Query: 1419 KTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKE---SELAILRLKMHENANHYET 1475 + + +QR+++ + QQ+ + + ++ + E + SE LR EN N ++ Sbjct: 1642 LNKQKKLEQSQRDNDL--LLQQVKQLQDKLNECQNELQVLKSENNQLRELSEENINQTQS 1699 Query: 1476 MQK--ESEIERV-KLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIE 1532 ++ ++++ ++ +L +L+ + S K++ EL L+ +A+ E Q + + Sbjct: 1700 IKALYQNQLFQISELRNDLSESEEKEGSNLKRIEELTNQLQNVLAE-KEKQRLNQEAGVN 1758 Query: 1533 IVTLNDEITNLQ--NMVRASSSKIQKHVSFASDTKQGRDE---QLDNTMNKE 1579 + ++ +Q + + +I+++ + Q ++E QL++ + K+ Sbjct: 1759 GILKEKQLIEIQLNEVTQTGLKQIEQYKQEIAQLNQEKEEIKKQLEDNLEKK 1810 Score = 138 bits (333), Expect = 2e-30 Identities = 266/1318 (20%), Positives = 573/1318 (43%), Gaps = 142/1318 (10%) Query: 317 EIANMTELTKKIEL-LEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGS--PLISRK 373 +I + K E+ ++HL QI+ ++E E++ T+ + + S+K S ++ + Sbjct: 639 DIQQQQIIIKDYEIQIDHLKNQIKYLSQEKEDQ-CKFTTQIASPTQSSRKDSIIKILQNE 697 Query: 374 SGRNT---ASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLN---KDLVDK--- 424 +N S++ S L E N + + IQ LN +DL++K Sbjct: 698 EIQNRDQQISELNDKISILDIEISNLQHQLESQIKLVQSRNEEIQHLNSQVRDLLEKQQY 757 Query: 425 -EYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQE 483 E +I+E + + + + + + + TN + + + ++ Sbjct: 758 FEQLINELNAYHQQSKNQQEVQIIKLEGVSYDISHNSFNFDALRTPTNQNYIIDEIQQEQ 817 Query: 484 QLKQELNDEIK---DVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQM 540 + L+ ++ + +K +I+ K EE I Q N I K + K N +L+ Q+ Sbjct: 818 SINSSLSSIVQMSPNTQIKQIIQLNKQQEENIIQKNRLIQ--EKEVDLEKQNEELQ--QL 873 Query: 541 QK-TIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVY 599 Q N ++++ N ++ +L E++ L ++ +++++ LV + + ++Y Sbjct: 874 QSINAKNEQEINELNLQLTQLHEKIETLREEQTQIQQQNDEYTKKLVIEKQSAIDQIELY 933 Query: 600 KKMIEM---------ENLAETRLKAISLLESQKFDLVQELHILQQKYDEVE--DKLADIS 648 KK I+ +AE R++ + + ++ L + I+QQ+ E++ + + Sbjct: 934 KKEIQQVKSINDQLSTQIAELRIQ-LQTNQEEQITLTENEQIIQQQNKEIQFLKTINNEK 992 Query: 649 QLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMN 708 Q+Q Q ++++ L+EQ D L + K L +I+ KE ++L+ K +++ Sbjct: 993 QIQISQQDYQLQN--LKEQFDHLKSKSKNL--IIKTNSAIKEIKIIHAEELQQIKVNLLQ 1048 Query: 709 KLQNYIQENMDLTDK---LEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIE 765 + Q + L K +E+ KI KI EQS +Q Q + +Q+ L IE Sbjct: 1049 EQQLLKYDMKQLETKFVAIEQSYQSKIYNAQVKILESEQSIVQFQEELKL-LQQSKLQIE 1107 Query: 766 NIESELS-KYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELV 824 + ++ + +++ ++ ++ LE+K QL ++ + + S++ Q ++ Sbjct: 1108 EKYCKAQDEFLEQSQFIDQQNTKLKSQKSQLEQKEKQL-QCIEIQIQEQSDHIEQSNQTT 1166 Query: 825 NRLAVLMDH-DRVVEKQLLE---IEHENKELQKKNQILLEENQNLQI---SLSDMQQHYN 877 L + ++ +++ +QL E I N++ +K Q+L ++ Q L++ L ++Q + Sbjct: 1167 KTLQLEINQLQQILSQQLQEKNLIHDLNQQNSEKQQLLQQKEQQLKVLHSELENLQLQLD 1226 Query: 878 ALVEKANRTDLAESESTKY---QTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNT 934 +V+ N+ + ++ + K Q+QL ES LK +T QTL Q K+ EF Sbjct: 1227 GIVQ--NQREKEQNLNVKILDQQSQLEQYESRLKEVT---QTL--QHNKQ------EFQN 1273 Query: 935 QIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQ 994 +I + + LNEK + NI + +LE +N E +NK LEL + + Sbjct: 1274 RINLIEQVNQDLNEKNQNNIVQIQKLE--------------INEELMNKKILEL-EFELA 1318 Query: 995 KQQTQSPDYTEQ--YIN-EINKLNALLK---QKDEEIIALNQKINNAQVSYMSMVSDYES 1048 K + +S + + IN + +KL LK QK + +I N K + ++ + Sbjct: 1319 KIRNESQEKARELSLINQDYHKLQDDLKKEIQKAQNLIDQNIKYEQDIIQLKQNLTTKDQ 1378 Query: 1049 KLAQFTTKL-----ENMEEEMQRVSKQLLDSKQ--HNEELQILVREQDDQIKELKETKLT 1101 +L +L +N + + Q K KQ + E ++L+ E +DQ+ K+ L Sbjct: 1379 QLVGLNEQLNVSIKQNQDIQSQYTLKVTQLEKQIINLEREKLLLNESNDQLIREKQNNLQ 1438 Query: 1102 FEM---NIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQ 1158 ++ N+ + + SS + + + + Q ++ F ++ +Q Sbjct: 1439 QQLTKQNLNEEKENATSSQEVKIQQLKDQLQKEQENIKQLQDSHQKQIQQYFNEKSQQIQ 1498 Query: 1159 E-QSAKLNTELQECYTKIIQLETLNTELTGHDVVN---------QEQINQLKSKLEQLNT 1208 + S N LQ +K I E LN ++N ++ I Q K++L+ + + Sbjct: 1499 QLTSNNDNLTLQLNESKQISNEHLNDNDKLKSIINNQLTQIKQFEQAIIQYKNQLQDVKS 1558 Query: 1209 ENDNLLSTVAELRSSISSAVDQR-GFEIAELWKQHLAQREADFQKTEHE-LRVQLSAFES 1266 +N+NL++ + + + ++ +Q ++++ ++H Q+++ T+ E L+ Q+ Sbjct: 1559 QNENLVTILHQSENKWTNLNEQNTQYKLSIQQQEHQIQQQSLLILTQEEALKKQIIINVD 1618 Query: 1267 KYEQLLD-SVQSSTQEETNKIVTMEQVTSLQNKLQDKE---EHLRNLQEKYADVINQIEI 1322 + ++L + + Q +++ ++ + + + L+ +D + + ++ LQ+K + N++++ Sbjct: 1619 QEKKLFEINNQLWQEQQVSEDLNLNKQKKLEQSQRDNDLLLQQVKQLQDKLNECQNELQV 1678 Query: 1323 LRS------EIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQ 1376 L+S E+ +E + +LR + ++ + ++ I E Q Sbjct: 1679 LKSENNQLRELSEENINQTQSIKALYQNQLFQISELRNDLSESEEKEGSNLKRIEELTNQ 1738 Query: 1377 LKKSSXXXXXXXXXXXXRVND-------AEAKVLELTH----QLELKDSEIYQKTHEYTI 1425 L+ VN E ++ E+T Q+E EI Q E Sbjct: 1739 LQNVLAEKEKQRLNQEAGVNGILKEKQLIEIQLNEVTQTGLKQIEQYKQEIAQLNQEKEE 1798 Query: 1426 TLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKE--SEIE 1483 Q D E +Q E +++ ++ E + E+ L+ K +EN E Q + +++ Sbjct: 1799 IKKQLEDNLEKKKQVEEELNQKVNNIRLEFQLEIDQLKQKQYENQKAIEDQQNQLIIQVQ 1858 Query: 1484 RVK-----LIEELNV---KITESVSLNKQVAELNKALEEEVAKTN-EMQTALENQEIE 1532 + K LI E+N +S N+Q+ NK L++ ++++N + + Q+IE Sbjct: 1859 QEKQQQNSLIAEINKIQNDFNNEMSKNQQLMHENKRLQKFLSQSNLDKDLMHDRQQIE 1916 Score = 136 bits (328), Expect = 6e-30 Identities = 275/1351 (20%), Positives = 573/1351 (42%), Gaps = 118/1351 (8%) Query: 321 MTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTAS 380 +T+L +KIE L QI+Q N E KL +K S + + + Sbjct: 891 LTQLHEKIETLREEQTQIQQQNDEYTKKLVI------------EKQSAIDQIELYKKEIQ 938 Query: 381 KMKSPWSQLSSETLNQDTDKKINKNE---IAKLEMVIQSLNKDLV-------DKEYVISE 430 ++KS QLS++ + N+ E + + E +IQ NK++ +K+ IS+ Sbjct: 939 QVKSINDQLSTQIAELRIQLQTNQEEQITLTENEQIIQQQNKEIQFLKTINNEKQIQISQ 998 Query: 431 KDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELN 490 +D + L ++ ++ +IH + + + Q+ LK ++ Sbjct: 999 QDYQLQNLKEQFDHLKSKSKNLIIKTNSAIKEIKIIHAEELQQIKVNLLQEQQLLKYDMK 1058 Query: 491 D-EIKDVNVKDLIE-KLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQ-KTIDNF 547 E K V ++ + K+ +A+ +I + I + + K+ KL++++ K D F Sbjct: 1059 QLETKFVAIEQSYQSKIYNAQVKILESEQSIVQFQEEL-KLLQQSKLQIEEKYCKAQDEF 1117 Query: 548 SKVSDS-NKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEME 606 + S +++ +L + L QK +L+ + +Q + + ++ +++ Sbjct: 1118 LEQSQFIDQQNTKLKSQKSQLEQKEKQLQCIEIQIQEQSDHIEQSNQTTKTLQLEINQLQ 1177 Query: 607 NLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADIS--QLQSDQVCSEIK---- 660 + +L+ +L+ ++ +LQQK +++ +++ QLQ D + + Sbjct: 1178 QILSQQLQEKNLIHDLNQQNSEKQQLLQQKEQQLKVLHSELENLQLQLDGIVQNQREKEQ 1237 Query: 661 --SVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENM 718 +V + +Q L + L V + L+ +K++ I +E +D+ K QN I + Sbjct: 1238 NLNVKILDQQSQLEQYESRLKEVTQTLQHNKQEFQNRINLIEQVNQDLNEKNQNNIVQIQ 1297 Query: 719 DLTDKLEKMSAEKISEL---LAKINHEEQSKIQTQFGIDA---KIQERDLYIE-----NI 767 L E M+ +KI EL LAKI +E Q K + I+ K+Q+ DL E N+ Sbjct: 1298 KLEINEELMN-KKILELEFELAKIRNESQEKARELSLINQDYHKLQD-DLKKEIQKAQNL 1355 Query: 768 ESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRL 827 + KY+ I +L++++ + + L +QL +++ Q S+YT++ +L ++ Sbjct: 1356 IDQNIKYEQDIIQLKQNLTTKDQQLVGLN---EQLNVSIKQNQDIQSQYTLKVTQLEKQI 1412 Query: 828 AVLMDHDRVVEK---QLLEIEHENKELQKKNQILLEENQNLQISLS-DMQQHYNALV-EK 882 L ++ + QL+ + N + Q Q L EE +N S +QQ + L E+ Sbjct: 1413 INLEREKLLLNESNDQLIREKQNNLQQQLTKQNLNEEKENATSSQEVKIQQLKDQLQKEQ 1472 Query: 883 ANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQ--KKKEIEDLEIEFNTQIESAI 940 N L +S + Q + ++++T + L +Q + K+I + + N +++S I Sbjct: 1473 ENIKQLQDSHQKQIQQYFNEKSQQIQQLTSNNDNLTLQLNESKQISNEHLNDNDKLKSII 1532 Query: 941 RDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQ---Q 997 ++ +++E+ I Q + QLQ+ K+ ENL + + L +++ Q + Q Sbjct: 1533 NNQLTQIKQFEQAI---IQYKNQLQDVKSQNENLVTILHQSENKWTNLNEQNTQYKLSIQ 1589 Query: 998 TQSPDYTEQYINEINKLNALLKQ------KDEEIIALNQKINNAQVSYMSMVSDYESKLA 1051 Q +Q + + + AL KQ +++++ +N ++ Q + + + KL Sbjct: 1590 QQEHQIQQQSLLILTQEEALKKQIIINVDQEKKLFEINNQLWQEQQVSEDLNLNKQKKLE 1649 Query: 1052 QFTTKLENMEEEMQRVSKQLLDS-KQHNEELQILVREQDDQIKELKETKLTFEMNIPKTE 1110 Q ++ +N + +Q+V KQL D + ELQ+L + +++Q++EL E + +I Sbjct: 1650 Q--SQRDN-DLLLQQV-KQLQDKLNECQNELQVL-KSENNQLRELSEENINQTQSIKALY 1704 Query: 1111 GMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQE 1170 + I + +D + + L Q + ++ Q A +N L+E Sbjct: 1705 QNQLFQ-ISELRNDLSESEEKEGSNLKRIEELTNQLQNVLAEKEKQRLNQEAGVNGILKE 1763 Query: 1171 CYTKIIQL-ETLNTELTGHDVVNQE--QINQLKSKLE-QLNTENDNLLSTVAELRSSISS 1226 IQL E T L + QE Q+NQ K +++ QL + EL +++ Sbjct: 1764 KQLIEIQLNEVTQTGLKQIEQYKQEIAQLNQEKEEIKKQLEDNLEKKKQVEEELNQKVNN 1823 Query: 1227 AVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKI 1286 + EI +L KQ + + + +++L +Q+ + + L+ + + N++ Sbjct: 1824 IRLEFQLEIDQL-KQKQYENQKAIEDQQNQLIIQVQQEKQQQNSLIAEINKIQNDFNNEM 1882 Query: 1287 VTMEQVTSLQNKLQ--------DKE-EHLRNLQEKYADVIN--QIEILRSE--IEDEKVA 1333 +Q+ +LQ DK+ H R E+ + IN + + LR + I D + Sbjct: 1883 SKNQQLMHENKRLQKFLSQSNLDKDLMHDRQQIEQGEEKINCDENKSLRQDNSISDRQQC 1942 Query: 1334 FXXXXXXXXXXXXXXXXDLRTE-NQSYKQMQEQS-ILNINEENAQLKKSSXXXXXXXXXX 1391 +++ NQ+ K + Q I + +EN +LK+ Sbjct: 1943 VSVLYAISGNASENFENQMKSSSNQNQKIIVLQDKIAQLYDENDKLKRQQLQSLDDFIEI 2002 Query: 1392 X-XRVNDA------EAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEY 1444 + +D E + L+ + SE+ + L ++++E +N+++ Y Sbjct: 2003 SPLKESDLIKQLRQEIETLKADKEQGRAKSELQLEIVNLEKKLIKKDEEMQNIKKGTYMY 2062 Query: 1445 EKRIEDLTYEKESELAILRLKMHENANH----------YETMQKESEIERVKLIE-ELNV 1493 E + + L AN YE +Q E + + E +L + Sbjct: 2063 IDMCEKAIVQDRDWMIDLNSLEERQANRWRIVCEKLVEYEQLQGEIMKNQNDIQELQLQL 2122 Query: 1494 KITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSK 1553 K E++S+ + + +++L+EE + + QE+E L E + L++ +++ Sbjct: 2123 KNKENLSIKSMIMKQSQSLDEEDIFSIRSTVSKLRQELEQEKL--ENSKLKSYLKSYLKD 2180 Query: 1554 IQKHVSFASDTKQGRDEQLDNTMNKELLDAV 1584 Q+ KQ +++++ NK L + + Sbjct: 2181 EQRFEVSNRQIKQEQNQRVKEE-NKSLRNRI 2210 Score = 121 bits (291), Expect = 2e-25 Identities = 227/1161 (19%), Positives = 501/1161 (43%), Gaps = 135/1161 (11%) Query: 475 VNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHK 534 +N I +++ QEL E K+ ++D+++KL +E ++ DE+ + K K ++ Sbjct: 106 INSILYLKQSKLQEL--ESKEQKMRDILQKLLKKQESKEKI-DEVKNILTFIAKEKQKYQ 162 Query: 535 LKL-----------KQMQKTIDNFSKVS-----------DSNKEIVRLTEELHHLSQKVA 572 LKL K+ QK + + V D K + ++ LS + Sbjct: 163 LKLPDNSLQQNNLSKEYQKIVTKYESVMIQINRLNQLIFDQIKPAYTCEDSIYQLSYNIK 222 Query: 573 ELEEEKGNLQLHLVDYDSGRMIES---DVYKKMIEMENLAETRLK--------------A 615 E+ ++ N+Q + + +S + YKK IE +N LK Sbjct: 223 EIIKQNSNVQKEIKQKEEESTKQSNKLEKYKKQIEQKNSQIDSLKMDVKNLNQQLQNQET 282 Query: 616 ISLL------ESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQID 669 I+ L +SQ+ D++Q+ I Q K E + + Q + +Q+ EIK + E++ Sbjct: 283 INSLNDCIKKQSQQIDILQQQIIEQNKILEQNETIIAKQQEKENQLFQEIKMIKC-EKVK 341 Query: 670 ALSASKKE---LALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQ----NYIQENMDLTD 722 +L + + I +L+ + +L ++++ ++ + + + + + +T+ Sbjct: 342 SLQQDEDDQIKYKNTINDLRQEINELNAQLENMYTEQAQLQQQFDEQEIEHKKSQIQMTN 401 Query: 723 KLEKMSAE--KISELLA--KINHEEQSKIQTQFGIDAKIQERDLYIEN-IESELSKYKSR 777 ++K E K +L+ KI +Q K Q Q +IQ+ + +N I+++LS+Y Sbjct: 402 TIQKFQLEVKKYQQLVEDNKIQFNQQLKQQQQ--QHKQIQQELINNQNSIQNQLSEY--- 456 Query: 778 ICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVV 837 ++ E++ E+ LE D L +++K + T L + M + Sbjct: 457 -LQIIENLKSKENLNQVLENLIDNLNLVIKQKLLQNLKST---SSLASSPMRGMSKNSSP 512 Query: 838 EKQLLEIEHENK-ELQKKNQIL--LEENQNLQISLSDMQQHYNALVEKANRTDLAESEST 894 +Q+L + N+ +LQK + L + E +++L + N + + + ES+ T Sbjct: 513 VRQILNHNNNNQIDLQKIHSTLDNISEQFLNRLNLLIKKDEKNQELIQHYCQQIEESQQT 572 Query: 895 KYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNI 954 Q D + + IT + L ++K ++++ + F+ + +S I N + ++ I Sbjct: 573 -IQQLCDDNDQQKQFITQMCKILNIEKIDDLKERK-SFSKEDQSYIETLNQNNAQIQQLI 630 Query: 955 EYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQ-----QTQSPDYTEQYIN 1009 Y +L+ +Q+ + I++ + ++ L K ++ + + + Q Q SP + + + Sbjct: 631 SYNQELQQDIQQQQIIIKDYEIQIDHL-KNQIKYLSQEKEDQCKFTTQIASPTQSSRKDS 689 Query: 1010 EINKL-NALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVS 1068 I L N ++ +D++I LN KI+ + ++ ES++ ++ E ++ +V Sbjct: 690 IIKILQNEEIQNRDQQISELNDKISILDIEISNLQHQLESQIKLVQSRNEEIQHLNSQV- 748 Query: 1069 KQLLDSKQHNEEL--------QILVREQDDQIKELK-------ETKLTFE-MNIPKTEGM 1112 + LL+ +Q+ E+L Q +Q+ QI +L+ F+ + P + Sbjct: 749 RDLLEKQQYFEQLINELNAYHQQSKNQQEVQIIKLEGVSYDISHNSFNFDALRTPTNQNY 808 Query: 1113 IISSTIEPMSDD---ANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQ 1169 II + S + ++ V L Q+EE IQ+ ++QE+ L + + Sbjct: 809 IIDEIQQEQSINSSLSSIVQMSPNTQIKQIIQLNKQQEENIIQKNRLIQEKEVDLEKQNE 868 Query: 1170 ECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVD 1229 E + QL+++N + Q+ QL K+E L E + E + Sbjct: 869 E----LQQLQSINAKNEQEINELNLQLTQLHEKIETLREEQTQIQQQNDEYTKKL-VIEK 923 Query: 1230 QRGFEIAELWKQHLAQREA--DFQKTE-HELRVQLSAFESKYEQLLDSVQSSTQEETNKI 1286 Q + EL+K+ + Q ++ D T+ ELR+QL + + L ++ Q Q++ +I Sbjct: 924 QSAIDQIELYKKEIQQVKSINDQLSTQIAELRIQLQTNQEEQITLTENEQ-IIQQQNKEI 982 Query: 1287 VTMEQVTS-LQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXX 1345 ++ + + Q ++ ++ L+NL+E Q + L+S+ ++ + Sbjct: 983 QFLKTINNEKQIQISQQDYQLQNLKE-------QFDHLKSKSKNLIIKTNSAIKEIKIIH 1035 Query: 1346 XXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVN--DAEAKVL 1403 ++ +QEQ +L + + + K + +V ++E ++ Sbjct: 1036 AEELQQIKV-----NLLQEQQLLKYDMKQLETKFVAIEQSYQSKIYNAQVKILESEQSIV 1090 Query: 1404 ELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILR 1463 + +L+L Q +Y + ++ + + QQ + + + L +KE +L + Sbjct: 1091 QFQEELKLLQQSKLQIEEKYCKAQDEFLEQSQFIDQQNTKLKSQKSQLE-QKEKQLQCIE 1149 Query: 1464 LKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQ 1523 +++ E ++H E + ++ +++ I +L +++ + + +LN+ + +E Q Sbjct: 1150 IQIQEQSDHIEQSNQTTKTLQLE-INQLQQILSQQLQEKNLIHDLNQ-------QNSEKQ 1201 Query: 1524 TALENQEIEIVTLNDEITNLQ 1544 L+ +E ++ L+ E+ NLQ Sbjct: 1202 QLLQQKEQQLKVLHSELENLQ 1222 Score = 96.3 bits (229), Expect = 6e-18 Identities = 179/917 (19%), Positives = 402/917 (43%), Gaps = 80/917 (8%) Query: 212 EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271 +D K+++ K Q N I +++ + +L +++ +KD ++ L E + +I ++ Sbjct: 1343 DDLKKEIQKAQ-NLIDQNIKYEQDIIQLKQNLTTKDQQLVGLNEQLNVSIKQNQDIQSQY 1401 Query: 272 SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELL 331 + +LE+ Q I E++ ++++ L N+ E + Sbjct: 1402 TLKVTQLEKQIINLEREKLLLNESNDQLIR---EKQNNLQQQ--LTKQNLNEEKENATSS 1456 Query: 332 EHLNCQIR--QTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWS-Q 388 + + Q Q KE EN + K + + S I + + N ++ S Q Sbjct: 1457 QEVKIQQLKDQLQKEQENIKQLQDSHQKQIQQYFNEKSQQIQQLTSNNDNLTLQLNESKQ 1516 Query: 389 LSSETLNQ-DTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDT 447 +S+E LN D K I N++ +++ Q++ + + V S+ + Sbjct: 1517 ISNEHLNDNDKLKSIINNQLTQIKQFEQAIIQYKNQLQDVKSQNENLVTILHQSENKWTN 1576 Query: 448 LIAQ-----LQLEHQQHMEGPSLIHVGTNTEDVNE--IAKVQEQLKQ-ELNDEI------ 493 L Q L ++ Q+H + + T E + + I V ++ K E+N+++ Sbjct: 1577 LNEQNTQYKLSIQQQEHQIQQQSLLILTQEEALKKQIIINVDQEKKLFEINNQLWQEQQV 1636 Query: 494 -KDVNVKDLIEKLKSAE-------EQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTID 545 +D+N+ +KL+ ++ +Q+ QL D+++ + +KS + +L+++ + + Sbjct: 1637 SEDLNLNKQ-KKLEQSQRDNDLLLQQVKQLQDKLNECQNELQVLKSENN-QLRELSE--E 1692 Query: 546 NFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSG-RMIESDVYKKMIE 604 N ++ ++ L ++E EE++G+ + + + + + ++ K+ + Sbjct: 1693 NINQTQSIKALYQNQLFQISELRNDLSESEEKEGSNLKRIEELTNQLQNVLAEKEKQRLN 1752 Query: 605 MENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHL 664 E LK L+E +Q + Q ++E +I+QL ++ EIK L Sbjct: 1753 QEAGVNGILKEKQLIE------IQLNEVTQTGLKQIEQYKQEIAQLNQEK--EEIKK-QL 1803 Query: 665 EEQIDALSASKKELALVIENLKLD--------KEQLYGTIKDLENDKEDIMNKLQNYIQE 716 E+ ++ ++EL + N++L+ K++ Y K +E+ + ++ ++Q Q+ Sbjct: 1804 EDNLEKKKQVEEELNQKVNNIRLEFQLEIDQLKQKQYENQKAIEDQQNQLIIQVQQEKQQ 1863 Query: 717 NMDLTDKLEKMSAEKISELLA--KINHEEQ--SKIQTQFGIDAKIQERDLYIENIESELS 772 L ++ K+ + +E+ ++ HE + K +Q +D + IE E +++ Sbjct: 1864 QNSLIAEINKIQNDFNNEMSKNQQLMHENKRLQKFLSQSNLDKDLMHDRQQIEQGEEKIN 1923 Query: 773 KYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMD 832 +++ R + SI+ + L + + + K+ S + L +++A L D Sbjct: 1924 CDENKSLRQDNSISDRQQCVSVLYAISGNASENFENQMKSSSNQNQKIIVLQDKIAQLYD 1983 Query: 833 HDRVVEKQLLEIEHENKELQ--KKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAE 890 + +++Q L+ + E+ K++ ++ + Q ++ +D +Q A E E Sbjct: 1984 ENDKLKRQQLQSLDDFIEISPLKESDLIKQLRQEIETLKADKEQG-RAKSELQLEIVNLE 2042 Query: 891 SESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKY 950 + K +++ N+K+ T+ + + + + D I+ N+ E +++ EK Sbjct: 2043 KKLIKKDEEMQ----NIKKGTYMYIDMCEKAIVQDRDWMIDLNSLEERQANRWRIVCEKL 2098 Query: 951 EKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINE 1010 +EY QL+ ++ + +N+I+ L + ++ NK NL + K + +Q+QS D E+ I Sbjct: 2099 ---VEY-EQLQGEIMKNQNDIQELQLQLK--NKENLSI--KSMIMKQSQSLD--EEDIFS 2148 Query: 1011 INKLNALLKQKDEEIIALNQKINNAQVSYMS-----MVSDYESKLAQFTTKLENMEEEMQ 1065 I + L+Q+ E+ N K+ + SY+ VS+ + K Q E + Sbjct: 2149 IRSTVSKLRQELEQEKLENSKLKSYLKSYLKDEQRFEVSNRQIKQEQNQRVKEENKSLRN 2208 Query: 1066 RVSKQLLDSKQHNEELQ 1082 R+S Q + KQ NE++Q Sbjct: 2209 RISDQQEEIKQLNEQIQ 2225 Score = 87.0 bits (206), Expect = 4e-15 Identities = 157/836 (18%), Positives = 350/836 (41%), Gaps = 74/836 (8%) Query: 719 DLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRI 778 D KL+K ++ + K + + Q+ + G K QER ++ + S L I Sbjct: 4 DQIAKLQKDLQIYKNQQVDKFDSDHQNLNKLMQGYQRKAQERKAIMKQLYSILKTKDQEI 63 Query: 779 CRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVE 838 L ++ D D +Q K+++ S+ QED++ V+ + + Sbjct: 64 EELSQTFECQMD---------DMNNKMIQLKEQSDSQLFQQEDKIKQIEQVINSILYLKQ 114 Query: 839 KQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDL--------AE 890 +L E+E + ++++ Q LL++ ++ + + +++ + ++ + L Sbjct: 115 SKLQELESKEQKMRDILQKLLKKQESKE-KIDEVKNILTFIAKEKQKYQLKLPDNSLQQN 173 Query: 891 SESTKYQTQLRDLESNLKRITHEHQTLIVQKKK--EIEDLEIEFNTQIESAIRDKKVLNE 948 + S +YQ + ES + +I +Q + Q K ED + + I+ I+ + + Sbjct: 174 NLSKEYQKIVTKYESVMIQINRLNQLIFDQIKPAYTCEDSIYQLSYNIKEIIKQNSNVQK 233 Query: 949 KYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYI 1008 + ++ E T+ +L++YK IE N ++ L KM+++ +++ +Q Q+T Sbjct: 234 EIKQKEEESTKQSNKLEKYKKQIEQKNSQIDSL-KMDVKNLNQQLQNQET---------- 282 Query: 1009 NEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVS 1068 IN LN +K++ ++I L Q+I + ++ E+ +A+ K + +E++ + Sbjct: 283 --INSLNDCIKKQSQQIDILQQQI----IEQNKILEQNETIIAKQQEKENQLFQEIKMIK 336 Query: 1069 KQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNV 1128 + + S Q +E+ QI + + I +L++ E+N + E M D + Sbjct: 337 CEKVKSLQQDEDDQI---KYKNTINDLRQE--INELN-AQLENMYTEQAQLQQQFDEQEI 390 Query: 1129 DXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGH 1188 + K Q E + Q+ ++++ + N +L++ + Q + + EL + Sbjct: 391 EHKKSQIQMTNTIQKFQLEVKKYQQ--LVEDNKIQFNQQLKQ---QQQQHKQIQQELINN 445 Query: 1189 DVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREA 1248 Q Q+++ +E L ++ +NL + L +++ + Q+ + + + Sbjct: 446 QNSIQNQLSEYLQIIENLKSK-ENLNQVLENLIDNLNLVIKQKLLQNLKSTSSLASSPMR 504 Query: 1249 DFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRN 1308 K +R Q+ + + L + S+ EQ + N L K+E + Sbjct: 505 GMSKNSSPVR-QILNHNNNNQIDLQKIHSTLDN------ISEQFLNRLNLLIKKDEKNQE 557 Query: 1309 LQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSIL 1368 L + Y I + + ++ D+ D E +S+ + + I Sbjct: 558 LIQHYCQQIEESQQTIQQLCDDNDQQKQFITQMCKILNIEKIDDLKERKSFSKEDQSYIE 617 Query: 1369 NINEENAQLKKSSXXXXXXXXXXXXR---VNDAEAKVLELTHQLEL----KDSEIYQKTH 1421 +N+ NAQ+++ + + D E ++ L +Q++ K+ + T Sbjct: 618 TLNQNNAQIQQLISYNQELQQDIQQQQIIIKDYEIQIDHLKNQIKYLSQEKEDQCKFTTQ 677 Query: 1422 EYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESE 1481 + T + R D + Q E + R + ++ E +++IL +++ N H Q ES+ Sbjct: 678 IASPTQSSRKDSIIKILQN-EEIQNRDQQIS-ELNDKISILDIEI-SNLQH----QLESQ 730 Query: 1482 IERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEM-QTALENQEIEIVTL 1536 I KL++ N +I S + + E + E+ + + N Q + QE++I+ L Sbjct: 731 I---KLVQSRNEEIQHLNSQVRDLLEKQQYFEQLINELNAYHQQSKNQQEVQIIKL 783 Score = 70.1 bits (164), Expect = 5e-10 Identities = 136/765 (17%), Positives = 313/765 (40%), Gaps = 77/765 (10%) Query: 823 LVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEK 882 L +++A L ++ + Q +++ + + Q N+++ + Q + M+Q Y+ L K Sbjct: 2 LNDQIAKLQKDLQIYKNQ--QVDKFDSDHQNLNKLMQGYQRKAQERKAIMKQLYSIL--K 57 Query: 883 ANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRD 942 ++ E T ++ Q+ D+ + + ++ + + + Q++ +I+ +E N+ + Sbjct: 58 TKDQEIEELSQT-FECQMDDMNNKMIQLKEQSDSQLFQQEDKIKQIEQVINSILYLKQSK 116 Query: 943 KKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPD 1002 + L K +K + + +L + QE K I+ + N+ L I K QK Q + PD Sbjct: 117 LQELESKEQKMRDILQKL-LKKQESKEKIDEVK-NI-------LTFIAKEKQKYQLKLPD 167 Query: 1003 YTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEE 1062 + Q N + ++ + + +I +N ++N + E + Q + ++ + + Sbjct: 168 NSLQQNNLSKEYQKIVTKYESVMIQIN-RLNQLIFDQIKPAYTCEDSIYQLSYNIKEIIK 226 Query: 1063 EMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISS-TIEPM 1121 + V K++ ++ + + + + QI++ + +M++ + + TI + Sbjct: 227 QNSNVQKEIKQKEEESTKQSNKLEKYKKQIEQKNSQIDSLKMDVKNLNQQLQNQETINSL 286 Query: 1122 SDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETL 1181 +D +++ + Q +++ +Q K N QE K+I+ E + Sbjct: 287 NDCIKKQSQQIDILQQQI----IEQNKILEQNETIIAKQQEKENQLFQEI--KMIKCEKV 340 Query: 1182 NTELTGHD--VVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELW 1239 + D + + IN L+ ++ +LN + +N+ + A+L Q+ F+ Sbjct: 341 KSLQQDEDDQIKYKNTINDLRQEINELNAQLENMYTEQAQL---------QQQFD----- 386 Query: 1240 KQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKL 1299 +Q + +++ Q T + QL KY+QL+ E NKI +Q+ Q + Sbjct: 387 EQEIEHKKSQIQMTNTIQKFQLEV--KKYQQLV---------EDNKIQFNQQLKQQQQQH 435 Query: 1300 QDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSY 1359 + ++ L N Q + NQ+ IE+ K +L + + Sbjct: 436 KQIQQELINNQNS---IQNQLSEYLQIIENLK---SKENLNQVLENLIDNLNLVIKQKLL 489 Query: 1360 KQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQK 1419 + ++ S L + K SS +++ L+ H SE + Sbjct: 490 QNLKSTSSLASSPMRGMSKNSSPVRQILNHNNNNQID------LQKIHSTLDNISEQFLN 543 Query: 1420 THEYTITLTQRNDEF-ENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQK 1478 I ++N E ++ QQ+ E ++ I+ L + + + + M K Sbjct: 544 RLNLLIKKDEKNQELIQHYCQQIEESQQTIQQLCDDNDQQKQFIT-----------QMCK 592 Query: 1479 ESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLND 1538 IE++ ++E E S + + + N +++ ++ E+Q ++ Q+I I Sbjct: 593 ILNIEKIDDLKERKSFSKEDQSYIETLNQNNAQIQQLISYNQELQQDIQQQQIIIKDYEI 652 Query: 1539 EITNLQNMVRASSSKIQKHVSF----ASDTKQGRDEQLDNTMNKE 1579 +I +L+N ++ S + + F AS T+ R + + + E Sbjct: 653 QIDHLKNQIKYLSQEKEDQCKFTTQIASPTQSSRKDSIIKILQNE 697 Score = 48.4 bits (110), Expect = 0.002 Identities = 95/518 (18%), Positives = 229/518 (44%), Gaps = 45/518 (8%) Query: 216 QQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLA 275 +++T +N +A + EKQRL +++ ++ + + +L+E E++ K Sbjct: 1733 EELTNQLQNVLA-----EKEKQRL-----NQEAGVNGILKEKQLIEIQLNEVTQTGLK-- 1780 Query: 276 QELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANM-TELTKKIELLEHL 334 ++EQ + KQ +E + E+K ++EE+ + ++ N+ E +I+ L+ Sbjct: 1781 -QIEQYKQEIAQLNQEKEEIKKQ-LEDNLEKKKQVEEELNQKVNNIRLEFQLEIDQLKQK 1838 Query: 335 NCQIRQTNKELENKLATMGTESK----AVSSPSKKGSPLISRKSGRNTASKMKSPWSQLS 390 + ++ ++ +N+L + K ++ + K + + +N ++ Q Sbjct: 1839 QYENQKAIEDQQNQLIIQVQQEKQQQNSLIAEINKIQNDFNNEMSKNQQLMHENKRLQKF 1898 Query: 391 SETLNQDTDKKINKNEIAKLEMVIQ-SLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLI 449 N D D ++ +I + E I NK L + + + Sbjct: 1899 LSQSNLDKDLMHDRQQIEQGEEKINCDENKSLRQDNSISDRQQCVSVLYAISGNASENFE 1958 Query: 450 AQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELND--EIKDVNVKDLIEKLKS 507 Q++ Q+ + L D N+ K++ Q Q L+D EI + DLI++L+ Sbjct: 1959 NQMKSSSNQNQKIIVLQDKIAQLYDEND--KLKRQQLQSLDDFIEISPLKESDLIKQLRQ 2016 Query: 508 AEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSK-----VSDSNKEIVRLTE 562 E + ++ A ++ +++ + K KL + + + N K + K IV+ + Sbjct: 2017 EIETLKADKEQGRAKSELQLEIVNLEK-KLIKKDEEMQNIKKGTYMYIDMCEKAIVQDRD 2075 Query: 563 ELHHLSQKVAELEEEKGN----LQLHLVDYD--SGRMI--ESDVYKKMIEMENLAETRLK 614 + L+ LEE + N + LV+Y+ G ++ ++D+ + ++++N +K Sbjct: 2076 WMIDLN----SLEERQANRWRIVCEKLVEYEQLQGEIMKNQNDIQELQLQLKNKENLSIK 2131 Query: 615 AISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSAS 674 ++ + +SQ D +++ ++ ++ +L + +L++ ++ S +KS +EQ +S + Sbjct: 2132 SMIMKQSQSLD-EEDIFSIRSTVSKLRQEL-EQEKLENSKLKSYLKSYLKDEQRFEVS-N 2188 Query: 675 KKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQN 712 ++ + +K + + L I D + + + + ++QN Sbjct: 2189 RQIKQEQNQRVKEENKSLRNRISDQQEEIKQLNEQIQN 2226 >UniRef50_A2FP55 Cluster: Viral A-type inclusion protein, putative; n=1; Trichomonas vaginalis G3|Rep: Viral A-type inclusion protein, putative - Trichomonas vaginalis G3 Length = 1974 Score = 141 bits (342), Expect = 1e-31 Identities = 233/1160 (20%), Positives = 496/1160 (42%), Gaps = 116/1160 (10%) Query: 472 TEDVNEIAKVQEQLKQEL----NDEIKDV-----NVKDLIEKLKSAEEQITQLNDEIDAA 522 TE + ++K + L +L +D +D+ + + + + + EE +Q+ E+++ Sbjct: 80 TEQIAALSKKNQDLSAKLEMFTHDTTEDILPRADSPRRSVRRYEDDEENTSQMKFEMESL 139 Query: 523 NK-NMI---KV-KSNHKLKLKQMQ--KTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELE 575 + N + K+ K +H L+ K+ + K ++N+ + S +++ E+ +K+ E + Sbjct: 140 QRENKVLTQKIEKLSHSLQNKKNREKKLVENYQQASQKFRDLRASYEQTTENYKKLLESK 199 Query: 576 EEKG--NLQL---HLVDYDSGRMIESDVYKKMIEMENLAETRLKAIS---LLESQKFDLV 627 ++ N+++ + D M+E + + ++E L +T LK +S LE++ + Sbjct: 200 KDDDIRNVEIMKQQIALNDEKHMLEKENTELKSKLEKLEQTNLKLVSENMALENKFTECA 259 Query: 628 QELHILQQKYDEVEDKLADISQLQSDQVCS-EIKSVHLEEQIDALSASKKELAL------ 680 + L+++YD++E ++I+ +Q E+ ++ + + ++K L+ Sbjct: 260 KGYQALKKEYDQLESAHSEINDKSEEQQKEVELLKANIVKVMKIQKRTEKNLSKAQDKCN 319 Query: 681 ----VIENLKLDKEQL--------------YGTIKDLENDKEDIMNKLQNYIQENMDLTD 722 ++++ +KE + Y +KDLE++ +++ + QEN DL Sbjct: 320 QQEQLLKSFNQEKENITKQLQECTGLLDKSYTRLKDLESNNKELSRVNKKLTQENEDLRG 379 Query: 723 KLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLE 782 + + A S++ + + +T + +++ + I++ +++ + +S++ +L+ Sbjct: 380 VNKNLKAA--SQISQSKDFQISKLNETINSLRSELDDTASKIKDSQNDATDLRSQLAQLQ 437 Query: 783 ESIAVMEDR--RYSLERKA--------DQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMD 832 E +E+R Y E KA ++ + Q E + E V + L Sbjct: 438 EEKFELENRCKEYEQELKAANDKISKSKEMSQNINSMQSDLKELNKLKSENVELKSKLEI 497 Query: 833 HDRVVEK--QLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAE 890 H + Q E+ EN EL++ +I EE QN + + + NA+ E + + Sbjct: 498 HSQKSFNRIQFEELRQENNELRETIRIAEEEEQNDTVHSNLL----NAIKEYYDENEELR 553 Query: 891 SESTKYQTQLRDLESNLKRITHEHQTLI-VQKKKEIEDLEIEFNTQIESAIRDKKV---L 946 + K QL+DL S L R H++ L + K ++E+ E++ + + E ++ KV L Sbjct: 554 KVNNKLTKQLKDLSSQLVRAQHQNMQLTDIINKSQLEEEELDSDEECEKLLKSPKVKTVL 613 Query: 947 NEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQ 1006 NE +E +L Q++E K E L N ++ + ++ Q D+ E Sbjct: 614 NELNSSLLEN-KELRRQVKELKQENEQLKQNSRLNDEEESPEVKLSEEEDQIFEEDFPEV 672 Query: 1007 YINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQR 1066 ++E N N+ ++ D E+I + KI Q Y ++ D ES A+ LE ++ E + Sbjct: 673 ELDESN--NSPEEKSDSELIPI--KIE-PQFIYNKIIDDEESN-AESDDNLEEVKSEEED 726 Query: 1067 VSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMI--ISSTIEPMSDD 1124 + + ++ +++EE + + +E + E N +E IS + +D Sbjct: 727 ANLEENNNSENSEENNNSEENNSEGSENSEENNNSEENNSEHSENSEEDISEEEKTKNDL 786 Query: 1125 ANNVDXXXXXXXXXXXXLKVQEEEEFI--QERSVLQEQSAKLNTELQECYTKIIQLETLN 1182 + +K QEE++ + +E + + E + KLN+ ++ ++ L N Sbjct: 787 IQQIGDLQKKVYFLNNGIKSQEEQKDVLHKENNQIIEHNEKLNSAVETLKRELSTLNLEN 846 Query: 1183 TELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRS-SISSAVDQRGFEIAELWKQ 1241 ++ + ++I +LK ++E+L NL E++S + D+ + E Sbjct: 847 EKIIEDNENKDKEIERLKEEIEKLKNHEMNLDELEKEIKSLEQENDDDEVNYLKKETEDL 906 Query: 1242 HLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQD 1301 +E F+ + +L ++ E + L+++ Q+ +EE + SL+ ++ + Sbjct: 907 EKMAKEVIFRNEKIQLEQKIRDLEEENRLLIENYQNGHEEEN--------LDSLEAQMTE 958 Query: 1302 KEEHLRNLQEKYADVINQIEILRS-EIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYK 1360 E + L + +VI++ E S E+E+ K AF T + Sbjct: 959 LMEMNQKLSRELDEVISKKENESSIEVEELKNAFTEANKQKEQVLKQYNTLKATYSLLLT 1018 Query: 1361 QMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKT 1420 Q + N E+ + + S N K LEL + DS+ + Sbjct: 1019 QYNDLKDQNNFEKVTETETSEIQSLKEENEKLKAYN----KSLELKF---MNDSDNVRFA 1071 Query: 1421 HEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEK-ESELAILRLKMHENANHYETMQKE 1479 HE T E ++Q++ YE++I+ L EK E E RL + E +++E Sbjct: 1072 HEET----------EKLKQKVTNYEEKIKTLEKEKKEHETEEQRL----SGKLKEFIKQE 1117 Query: 1480 SEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDE 1539 + L+ E +L K + +LN L++ + + + + N+E EI Sbjct: 1118 EDFG--VLLGNYKKLNEEKTNLEKSLNKLNDDLQKVTKENEKNKIIISNRETEISMYQHA 1175 Query: 1540 ITNLQNMVRASSSKIQKHVS 1559 T QN + + ++Q V+ Sbjct: 1176 NTAQQNDLARENQQLQNQVT 1195 Score = 141 bits (341), Expect = 2e-31 Identities = 269/1333 (20%), Positives = 557/1333 (41%), Gaps = 120/1333 (9%) Query: 311 EEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLI 370 +EK LE N TEL K+E LE N ++ N LENK +K + K+ L Sbjct: 218 DEKHMLEKEN-TELKSKLEKLEQTNLKLVSENMALENKFTEC---AKGYQALKKEYDQLE 273 Query: 371 SRKSGRNTASKMKSPWSQLSSET------LNQDTDKKINK--NEIAKLEMVIQSLNKDLV 422 S S N S+ + +L + + T+K ++K ++ + E +++S N++ Sbjct: 274 SAHSEINDKSEEQQKEVELLKANIVKVMKIQKRTEKNLSKAQDKCNQQEQLLKSFNQEKE 333 Query: 423 DKEYVISEKDTXXXXXXXXXXGKDTLIAQL-QLEHQQHMEGPSLIHVGTNTEDVNEIAKV 481 + + E ++ +L ++ + E L V N + ++I++ Sbjct: 334 NITKQLQECTGLLDKSYTRLKDLESNNKELSRVNKKLTQENEDLRGVNKNLKAASQISQS 393 Query: 482 QEQLKQELNDEIKDV--NVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQ 539 ++ +LN+ I + + D K+K ++ T L ++ + ++++ K ++ Sbjct: 394 KDFQISKLNETINSLRSELDDTASKIKDSQNDATDLRSQLAQLQEEKFELENRCKEYEQE 453 Query: 540 MQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVY 599 ++ D SK + ++ I + +L L++ +E E K L++H S I+ + Sbjct: 454 LKAANDKISKSKEMSQNINSMQSDLKELNKLKSENVELKSKLEIH--SQKSFNRIQFEEL 511 Query: 600 KKMIEMENLAETRLKAISLLESQKFDLVQE--LHILQQKYDEVEDKLADISQLQSDQVCS 657 ++ E L ET A E ++ D V L+ +++ YDE E+ L + ++++ Sbjct: 512 RQ--ENNELRETIRIA---EEEEQNDTVHSNLLNAIKEYYDENEE-LRKV----NNKLTK 561 Query: 658 EIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYG---TIKDLENDK-EDIMNKLQNY 713 ++K L Q+ +L +I +L++E+L K L++ K + ++N+L + Sbjct: 562 QLKD--LSSQLVRAQHQNMQLTDIINKSQLEEEELDSDEECEKLLKSPKVKTVLNELNSS 619 Query: 714 IQENMDLTDKLEKMSAEKIS-ELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELS 772 + EN +L +++++ E + +++N EE+S + +I E D +E + S Sbjct: 620 LLENKELRRQVKELKQENEQLKQNSRLNDEEESPEVKLSEEEDQIFEED--FPEVELDES 677 Query: 773 KYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMD 832 E I + + ++ + D E+ A S+ ++E + A L + Sbjct: 678 NNSPEEKSDSELIPIKIEPQFIYNKIID------DEESNAESDDNLEEVKSEEEDANLEE 731 Query: 833 HDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALV--EKANRTDLAE 890 ++ + EN +N EEN N + + S+ ++ + E+ + DL + Sbjct: 732 NNNSENSEENNNSEENNSEGSENS---EENNNSEENNSEHSENSEEDISEEEKTKNDLIQ 788 Query: 891 SESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKY 950 + Q ++ L + +K + L + + IE E + N+ +E+ R+ LN + Sbjct: 789 -QIGDLQKKVYFLNNGIKSQEEQKDVLHKENNQIIEHNE-KLNSAVETLKRELSTLNLEN 846 Query: 951 EKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINE 1010 EK IE + +++ K IE L + ++MNL+ ++K ++ + ++ D +N Sbjct: 847 EKIIEDNENKDKEIERLKEEIEKL-----KNHEMNLDELEKEIKSLEQENDD---DEVNY 898 Query: 1011 INKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQ 1070 + K L++ +E+I N+KI Q+ + E++L + + EE + + Q Sbjct: 899 LKKETEDLEKMAKEVIFRNEKI---QLEQKIRDLEEENRLLIENYQNGHEEENLDSLEAQ 955 Query: 1071 LLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDX 1130 + + + N++L RE D+ I + KE + + E+ K + E + N + Sbjct: 956 MTELMEMNQKLS---RELDEVISK-KENESSIEVEELKNAFTEANKQKEQVLKQYNTLKA 1011 Query: 1131 XXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDV 1190 LK Q E + E + QS K E + Y K ++L+ +N D Sbjct: 1012 TYSLLLTQYNDLKDQNNFEKVTETETSEIQSLKEENEKLKAYNKSLELKFMN------DS 1065 Query: 1191 VNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADF 1250 N ++ KL+Q T + + T+ + + + + ++ E KQ E DF Sbjct: 1066 DNVRFAHEETEKLKQKVTNYEEKIKTLEKEKKEHETEEQRLSGKLKEFIKQ-----EEDF 1120 Query: 1251 ---QKTEHELRVQLSAFESKYEQLLDSVQSSTQE-ETNKIVTMEQVTSLQNKLQDKEEHL 1306 +L + + E +L D +Q T+E E NKI+ + T + Sbjct: 1121 GVLLGNYKKLNEEKTNLEKSLNKLNDDLQKVTKENEKNKIIISNRETEISMYQHANTAQQ 1180 Query: 1307 RNLQEKYADVINQIEILRSEIE--DEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQE 1364 +L + + NQ+ L+ E+ +KV L E +Q + Sbjct: 1181 NDLARENQQLQNQVTSLQKEVTSLQDKVTSLQTSNGDNSDAEDTINGLEAEITDLQQKFD 1240 Query: 1365 QSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELT---HQL-----ELKDSEI 1416 + EE + +K + + +LT QL +LK S+ Sbjct: 1241 NLTEDFEEEKSSHEKDVEELSQTIEGLNKLCEEQHNTISQLTLKASQLQSEIDQLKPSDS 1300 Query: 1417 YQKTHEYTITL-------TQRN-DEFENVRQQLVEYEKRIEDLTYEKE-----------S 1457 + Y++ + Q N +E EN+ +Q E K E+ E+E + Sbjct: 1301 SKPKPNYSVFVKLDLEKPEQPNFNEEENLNEQNEEENKEEEEENKEEEENQNNEEEDDDN 1360 Query: 1458 ELAILRLKMHENANHYETMQKE-SEIERVKLIEELNVKITESVSLNKQVAELNKALEEEV 1516 + +L ++ E + ++K+ +++E+ K E + ++ ++ E N ++ ++ Sbjct: 1361 DNEMLMYQIQEQSREISKLKKQLNKLEKDK--ENADAAFKTAMDRVHELEEENTLMKHKI 1418 Query: 1517 AK--TNEMQTALENQEIEIVTLNDEITNLQNMVRAS-SSKIQKHVSFASDTK---QGRDE 1570 E + +LE + +I L E + LQ V + S+ +Q+ FA + + Q +D Sbjct: 1419 DSDGVKEDKPSLEEMKGKIDLLEYENSKLQQQVSSQPSTPVQQKNDFAENIEEQIQQKDS 1478 Query: 1571 QLDNTMNKELLDA 1583 +++ + +EL DA Sbjct: 1479 EIEK-LKEELADA 1490 Score = 136 bits (328), Expect = 6e-30 Identities = 256/1228 (20%), Positives = 517/1228 (42%), Gaps = 104/1228 (8%) Query: 140 QLGD----VTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTX 195 Q+GD V L+N IK ++ VL + I++ EK+N + ++ + Sbjct: 789 QIGDLQKKVYFLNNGIKSQEEQKDVLHKE----NNQIIEHNEKLNSAVETLKRELSTLNL 844 Query: 196 XXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESK--DVRISSL 253 E K+++ K++ + + + DE ++ +K +E + D ++ L Sbjct: 845 ENEKIIEDNENKDKEIERLKEEIEKLKNHEMNL-----DELEKEIKSLEQENDDDEVNYL 899 Query: 254 EEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEK 313 ++ + LE E+ + K+ +LEQ L ++ + EE E Sbjct: 900 KKETEDLEKMAKEVIFRNEKI--QLEQKIRDLEEENR----LLIENYQNGHEE----ENL 949 Query: 314 GSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRK 373 SLE A MTEL +E+ + L+ ++ + + EN+ + E K + + K + ++ Sbjct: 950 DSLE-AQMTEL---MEMNQKLSRELDEVISKKENESSIEVEELKNAFTEANKQKEQVLKQ 1005 Query: 374 SGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDT 433 NT S ++ +Q+ +K+ + E ++++ + + N+ L + K Sbjct: 1006 Y--NTLKATYSLLLTQYNDLKDQNNFEKVTETETSEIQSLKEE-NEKLKAYNKSLELKFM 1062 Query: 434 XXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEI 493 + + Q +++ ++ TE+ K++E +KQE + + Sbjct: 1063 NDSDNVRFAHEETEKLKQKVTNYEEKIKTLEKEKKEHETEEQRLSGKLKEFIKQEEDFGV 1122 Query: 494 KDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVK---SNHKLKLKQMQKTIDNFSKV 550 N K L E+ + E+ + +LND++ K K K SN + ++ Q N ++ Sbjct: 1123 LLGNYKKLNEEKTNLEKSLNKLNDDLQKVTKENEKNKIIISNRETEISMYQHA--NTAQQ 1180 Query: 551 SDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVD----YDSGRMIESDVYKKMIEME 606 +D +E +L ++ L ++V L+++ +LQ D D+ +E+++ + + Sbjct: 1181 NDLARENQQLQNQVTSLQKEVTSLQDKVTSLQTSNGDNSDAEDTINGLEAEITDLQQKFD 1240 Query: 607 NLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEE 666 NL E + S E +L Q + L + +E + ++ ++ L++ Q+ SEI + + Sbjct: 1241 NLTEDFEEEKSSHEKDVEELSQTIEGLNKLCEEQHNTISQLT-LKASQLQSEIDQLKPSD 1299 Query: 667 QIDALSASKKELALVIENLK---LDKEQLYGTIKDLENDKEDIMNK----LQNYIQENMD 719 + L +E + ++E+ + EN +E+ NK QN +E+ D Sbjct: 1300 SSKPKPNYSVFVKLDLEKPEQPNFNEEENLNEQNEEENKEEEEENKEEEENQNNEEEDDD 1359 Query: 720 LTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRIC 779 +++ ++ S ++K+ + + + DA + + +E E + K +I Sbjct: 1360 NDNEMLMYQIQEQSREISKLKKQLNKLEKDKENADAAFKTAMDRVHELEEENTLMKHKI- 1418 Query: 780 RLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEK 839 +S V ED+ SLE ++ E K + + Q V + D +E+ Sbjct: 1419 ---DSDGVKEDKP-SLEEMKGKIDLLEYENSKLQQQVSSQPSTPVQQ---KNDFAENIEE 1471 Query: 840 QLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRT-DLAESESTKYQT 898 Q I+ ++ E++K + L + ++L+ +L+ + +L +++T D E + ++ Sbjct: 1472 Q---IQQKDSEIEKLKEELADAKEDLKYALAKLDDANTSLTLNSSQTKDEEEDDLESLKS 1528 Query: 899 QLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYE------K 952 Q+ +LE + + L +K KE+ F QIE K + +KY+ K Sbjct: 1529 QVNELEEQRDFYIKKSENL-EEKVKELTRKVTNFKPQIEETKTPKSNIEDKYQNLQTVNK 1587 Query: 953 NI-EYVTQLEAQL----QEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQY 1007 + E ++ E Q+ + KN E + N E+NK+ +E D ++ Q QS D + Sbjct: 1588 GLAEEISAKEKQIDLLNSQIKNKEEQIKQNESEINKLFVEKNDLKIKLQ--QSSDELAAF 1645 Query: 1008 INEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRV 1067 E +++ ++KDE + VSY + + K+ + + + + E+ Sbjct: 1646 KRERSEVK---REKDEAVKKCQDLEKVLAVSY-----EQDDKIQELERENQKLNEQYLFA 1697 Query: 1068 SKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPK--TEGMIISSTIEPMSDDA 1125 + Q DS + +ELQ +E ++I L+ L E + + E + + D Sbjct: 1698 ADQCKDSNKQRDELQKENKELIEKINNLENDLLQAEKELDELTDEKEKLEEELSQAKKDL 1757 Query: 1126 NNVDXXXXXXXXXXXXLKVQ--EEEEFIQERSV----LQEQSAKLNTELQECYTKIIQLE 1179 + +K Q E+E I E+SV L Q+ KLN E++E + + E Sbjct: 1758 SQSKRQLQESKDDLFQIKKQMAEKERTISEQSVSIEDLGNQNDKLNEEIEEIQKEKDENE 1817 Query: 1180 TLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAEL---RSSISSAVDQRGFEIA 1236 +L + Q + + LKS+ QL + DNL + + E I + ++A Sbjct: 1818 EKLKDLQEKLKIAQSKADSLKSQNNQLIKDRDNLQNQLNEFLLDGGKIDEKLVSENKQLA 1877 Query: 1237 ELWKQHLAQREADFQKTEHELRVQLSAFES-KYEQLLDSVQSSTQEETNKIVTMEQVTSL 1295 E K + Q A + E RV A E E+ ++S+Q S + NK Q+ L Sbjct: 1878 E--KVQILQAHA-IKNIEGGSRVSAKAEEDPALERKVESLQVSL-DGANK-----QIQEL 1928 Query: 1296 QNKLQDKEEHLRNLQEKYADVINQIEIL 1323 Q K + E L+ K ++ I + +L Sbjct: 1929 QKKNNELNELNGVLRSKLSNAIKEKTLL 1956 Score = 125 bits (301), Expect = 1e-26 Identities = 181/963 (18%), Positives = 422/963 (43%), Gaps = 71/963 (7%) Query: 665 EEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKL 724 + QI +L+ ++L + + L T DL+ D+ + ++ ++N DL+ KL Sbjct: 38 QTQIKSLTDQVQDLEARLSSPTKTDTSLVKTCNDLQKDRSKLTEQIAALSKKNQDLSAKL 97 Query: 725 EKMSAEKISELLAKINH----------EEQSKIQTQFGIDAKIQERDLYIENIES---EL 771 E + + ++L + + +E++ Q +F +++ +E + + IE L Sbjct: 98 EMFTHDTTEDILPRADSPRRSVRRYEDDEENTSQMKFEMESLQRENKVLTQKIEKLSHSL 157 Query: 772 SKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLM 831 K+R +L E+ + L +Q ++ ++ + I+ E++ + L Sbjct: 158 QNKKNREKKLVENYQQASQKFRDLRASYEQTTENYKKLLESKKDDDIRNVEIMKQQIALN 217 Query: 832 DHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAES 891 D ++EK+ E++ + ++L++ N L+ EN L+ ++ + Y AL ++ ++ + A S Sbjct: 218 DEKHMLEKENTELKSKLEKLEQTNLKLVSENMALENKFTECAKGYQALKKEYDQLESAHS 277 Query: 892 E----STKYQTQLRDLESNLKRI------THEHQTLIVQKKKEIEDLEIEFNTQIESAIR 941 E S + Q ++ L++N+ ++ T ++ + K + E L FN + E+ + Sbjct: 278 EINDKSEEQQKEVELLKANIVKVMKIQKRTEKNLSKAQDKCNQQEQLLKSFNQEKENITK 337 Query: 942 DKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSP 1001 + +K+ + LE+ +E + L E+L +N L Q +QS Sbjct: 338 QLQECTGLLDKSYTRLKDLESNNKELSRVNKKLTQENEDLRGVNKNL---KAASQISQSK 394 Query: 1002 DYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENME 1061 D+ +NE +N+L + D+ + N+A S ++ + + + + + E Sbjct: 395 DFQISKLNE--TINSLRSELDDTASKIKDSQNDA-TDLRSQLAQLQEEKFELENRCKEYE 451 Query: 1062 EEMQRVSKQLLDSKQHNEELQIL---VREQDDQIKELKETKLTFEMNIPKTEGMIISSTI 1118 +E++ + ++ SK+ ++ + + ++E + E E K E++ K+ I + Sbjct: 452 QELKAANDKISKSKEMSQNINSMQSDLKELNKLKSENVELKSKLEIHSQKSFNRIQFEEL 511 Query: 1119 EPMSDDANNVDXXXXXXXXXXXXLK--VQEEEEFIQERSVLQEQSAKLNTELQECYTKII 1176 +++ + +E+ E L++ + KL +L++ ++++ Sbjct: 512 RQENNELRETIRIAEEEEQNDTVHSNLLNAIKEYYDENEELRKVNNKLTKQLKDLSSQLV 571 Query: 1177 QLETLNTELTGHDVVNQEQI--NQLKSKLE-QLNTENDNLLSTVAELRSSISSAVDQRGF 1233 + + N +LT D++N+ Q+ +L S E + ++ + + + EL SS+ + R Sbjct: 572 RAQHQNMQLT--DIINKSQLEEEELDSDEECEKLLKSPKVKTVLNELNSSLLENKELRR- 628 Query: 1234 EIAELWKQH-LAQREADFQKTEHELRVQLS-----AFESKYEQL-LDSVQSSTQEET-NK 1285 ++ EL +++ ++ + E V+LS FE + ++ LD +S +E++ ++ Sbjct: 629 QVKELKQENEQLKQNSRLNDEEESPEVKLSEEEDQIFEEDFPEVELDESNNSPEEKSDSE 688 Query: 1286 IVTME-QVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXX 1344 ++ ++ + + NK+ D E E A+ + +E ++SE ED + Sbjct: 689 LIPIKIEPQFIYNKIIDDE-------ESNAESDDNLEEVKSEEEDANL--EENNNSENSE 739 Query: 1345 XXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLE 1404 + +E + S N +E + ++ ++ D + KV Sbjct: 740 ENNNSEENNSEGSENSEENNNSEENNSEHSENSEEDISEEEKTKNDLIQQIGDLQKKVYF 799 Query: 1405 LTHQLELKD--SEIYQKTHEYTITLTQR-NDEFENVRQQL----VEYEKRIEDLTYEKES 1457 L + ++ ++ ++ K + I ++ N E ++++L +E EK IED K+ Sbjct: 800 LNNGIKSQEEQKDVLHKENNQIIEHNEKLNSAVETLKRELSTLNLENEKIIED-NENKDK 858 Query: 1458 ELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVA 1517 E+ L+ ++ + NH E E E E +K +E+ N E L K+ +L K +E + Sbjct: 859 EIERLKEEIEKLKNH-EMNLDELEKE-IKSLEQEN-DDDEVNYLKKETEDLEKMAKEVIF 915 Query: 1518 KTNEMQTALENQEIEIVTLNDEITNLQN-MVRASSSKIQKHVSFASDTKQGRDEQLDNTM 1576 + ++Q + +++E I N QN + ++ ++ + Q +LD + Sbjct: 916 RNEKIQLEQKIRDLEEEN-RLLIENYQNGHEEENLDSLEAQMTELMEMNQKLSRELDEVI 974 Query: 1577 NKE 1579 +K+ Sbjct: 975 SKK 977 Score = 123 bits (297), Expect = 4e-26 Identities = 296/1499 (19%), Positives = 613/1499 (40%), Gaps = 153/1499 (10%) Query: 154 KDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXX------XXXXXXXXXX 207 K N + V++++ K E + Q+K N+++Q++++ N+ Sbjct: 294 KANIVKVMKIQ-KRTEKNLSKAQDKCNQQEQLLKSFNQEKENITKQLQECTGLLDKSYTR 352 Query: 208 XXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLL---KDIESKDVRISSLEEANKLLEAAR 264 E ++++++ + + + + L + +SKD +IS L N+ + + R Sbjct: 353 LKDLESNNKELSRVNKKLTQENEDLRGVNKNLKAASQISQSKDFQISKL---NETINSLR 409 Query: 265 FEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTEL 324 E+ SK+ Q K +E C+E + + + +I+ E+ Sbjct: 410 SELDDTASKIKDS--QNDATDLRSQLAQLQEEKFELENRCKEYEQELKAANDKISKSKEM 467 Query: 325 TKKIEL----LEHLNCQIRQTNKELENKLATMGTES-KAVSSPSKKGSPLISRKSGRNTA 379 ++ I L+ LN +++ N EL++KL +S + + R++ R Sbjct: 468 SQNINSMQSDLKELN-KLKSENVELKSKLEIHSQKSFNRIQFEELRQENNELRETIRIAE 526 Query: 380 SKMKSPWSQLSSETLNQDTDKKINKNEIAK----LEMVIQSLNKDLVDKEYV------IS 429 + ++ + S LN + E+ K L ++ L+ LV ++ I Sbjct: 527 EEEQN--DTVHSNLLNAIKEYYDENEELRKVNNKLTKQLKDLSSQLVRAQHQNMQLTDII 584 Query: 430 EKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQE- 488 K + L+ +++ + SL+ V E+ + EQLKQ Sbjct: 585 NKSQLEEEELDSDEECEKLLKSPKVKTVLNELNSSLLENKELRRQVKELKQENEQLKQNS 644 Query: 489 -LNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKL---KLKQM---Q 541 LNDE + VK E+ + EE ++ E+D +N N + KS+ +L K++ Sbjct: 645 RLNDEEESPEVKLSEEEDQIFEEDFPEV--ELDESN-NSPEEKSDSELIPIKIEPQFIYN 701 Query: 542 KTIDN--FSKVSDSNKEIVRLTEELHHLSQKV-AELEEEKGNLQLHLVDYDSGRMIESDV 598 K ID+ + SD N E V+ EE +L + +E EE N + + + + E + Sbjct: 702 KIIDDEESNAESDDNLEEVKSEEEDANLEENNNSENSEENNNSEEN--NSEGSENSEENN 759 Query: 599 YKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSE 658 + E+ +E + IS E K DL+Q++ LQ+K + + + + Q D + E Sbjct: 760 NSEENNSEH-SENSEEDISEEEKTKNDLIQQIGDLQKKVYFLNNGIKSQEE-QKDVLHKE 817 Query: 659 IKSV--HLEEQIDALSASKKELA-LVIENLKL-------DKE--QLYGTIKDLENDK--- 703 + H E+ A+ K+EL+ L +EN K+ DKE +L I+ L+N + Sbjct: 818 NNQIIEHNEKLNSAVETLKRELSTLNLENEKIIEDNENKDKEIERLKEEIEKLKNHEMNL 877 Query: 704 EDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLY 763 +++ ++++ QEN D K E + ++ ++ + KIQ + I +E L Sbjct: 878 DELEKEIKSLEQENDDDEVNYLKKETEDLEKMAKEVIFRNE-KIQLEQKIRDLEEENRLL 936 Query: 764 IENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSY--------LQEKQKAYSE 815 IEN ++ + + LE + + + L R+ D++ S ++E + A++E Sbjct: 937 IENYQN--GHEEENLDSLEAQMTELMEMNQKLSRELDEVISKKENESSIEVEELKNAFTE 994 Query: 816 YTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQH 875 Q+++++ + L ++ Q +++ +N +K + E Q+L+ ++ + Sbjct: 995 ANKQKEQVLKQYNTLKATYSLLLTQYNDLKDQNN-FEKVTETETSEIQSLKEENEKLKAY 1053 Query: 876 YNALVEK-ANRTD---LAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIE 931 +L K N +D A E+ K + ++ + E +K + E KKE E E Sbjct: 1054 NKSLELKFMNDSDNVRFAHEETEKLKQKVTNYEEKIKTLEKE--------KKEHETEEQR 1105 Query: 932 FNTQIESAIRDKK---VLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLEL 988 + +++ I+ ++ VL Y+K E T LE L + ++++ + E+ NK+ + Sbjct: 1106 LSGKLKEFIKQEEDFGVLLGNYKKLNEEKTNLEKSLNKLNDDLQKVTKENEK-NKIIISN 1164 Query: 989 IDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSY------MSM 1042 + + Q + E +L + +E+ +L K+ + Q S Sbjct: 1165 RETEISMYQHANTAQQNDLARENQQLQNQVTSLQKEVTSLQDKVTSLQTSNGDNSDAEDT 1224 Query: 1043 VSDYESKLAQFTTKLENM----EEEMQRVSKQLLDSKQHNEELQILVREQDDQIKEL--K 1096 ++ E+++ K +N+ EEE K + + Q E L L EQ + I +L K Sbjct: 1225 INGLEAEITDLQQKFDNLTEDFEEEKSSHEKDVEELSQTIEGLNKLCEEQHNTISQLTLK 1284 Query: 1097 ETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSV 1156 ++L E++ K SS +P N EEE ++ Sbjct: 1285 ASQLQSEIDQLKPSD---SSKPKP------NYSVFVKLDLEKPEQPNFNEEENLNEQNEE 1335 Query: 1157 LQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQE-QINQLKSKLEQLNTENDNLLS 1215 ++ + N E +E + + + E+ + + Q +I++LK +L +L + +N + Sbjct: 1336 ENKEEEEENKEEEENQNNEEEDDDNDNEMLMYQIQEQSREISKLKKQLNKLEKDKENADA 1395 Query: 1216 TVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFE-SKYEQLLDS 1274 + ++ ++ + + + + E + ++ L +E SK +Q + S Sbjct: 1396 AFKTAMDRVHELEEENTLMKHKIDSDGVKEDKPSLE--EMKGKIDLLEYENSKLQQQVSS 1453 Query: 1275 VQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAF 1334 S+ ++ N +++ ++Q K+ + L+E+ AD ++ ++++D + Sbjct: 1454 QPSTPVQQKNDFAE-----NIEEQIQQKDSEIEKLKEELADAKEDLKYALAKLDDANTSL 1508 Query: 1335 XXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSIL---NINEENAQLK------------- 1378 L+++ ++ ++ I N+ E+ +L Sbjct: 1509 TLNSSQTKDEEEDDLESLKSQVNELEEQRDFYIKKSENLEEKVKELTRKVTNFKPQIEET 1568 Query: 1379 KSSXXXXXXXXXXXXRVN-------DAEAKVLELTH-QLELKDSEIYQKTHEYTITLTQR 1430 K+ VN A+ K ++L + Q++ K+ +I Q E ++ Sbjct: 1569 KTPKSNIEDKYQNLQTVNKGLAEEISAKEKQIDLLNSQIKNKEEQIKQNESEINKLFVEK 1628 Query: 1431 ND---EFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERV-- 1485 ND + + +L +++ ++ EK+ + + A YE K E+ER Sbjct: 1629 NDLKIKLQQSSDELAAFKRERSEVKREKDEAVKKCQDLEKVLAVSYEQDDKIQELERENQ 1688 Query: 1486 KLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQ 1544 KL E+ + NKQ EL K +E + K N ++ L E E+ L DE L+ Sbjct: 1689 KLNEQYLFAADQCKDSNKQRDELQKENKELIEKINNLENDLLQAEKELDELTDEKEKLE 1747 Score = 111 bits (267), Expect = 2e-22 Identities = 251/1382 (18%), Positives = 573/1382 (41%), Gaps = 102/1382 (7%) Query: 220 KMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELE 279 + Q + E E + RL + ES +V++S EE +++ E E+ L+ S + E E Sbjct: 627 RRQVKELKQENEQLKQNSRLNDEEESPEVKLS--EEEDQIFEEDFPEVELDESNNSPE-E 683 Query: 280 QXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIR 339 + + + I+ +E++ E +LE E +E E+ N + Sbjct: 684 KSDSELIPIKIEPQFIYNKIID---DEESNAESDDNLEEVKSEEEDANLE--ENNNSENS 738 Query: 340 QTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTD 399 + N E + G+E+ ++ S++ + S S + + + K+ + L + D Sbjct: 739 EENNNSEENNSE-GSENSEENNNSEENNSEHSENSEEDISEEEKTK-NDLIQQI--GDLQ 794 Query: 400 KKIN--KNEIAKLEM---VIQSLNKDLVD-KEYVISEKDTXXXXXXXXXXGKDTLIAQLQ 453 KK+ N I E V+ N +++ E + S +T + +I + Sbjct: 795 KKVYFLNNGIKSQEEQKDVLHKENNQIIEHNEKLNSAVETLKRELSTLNLENEKIIEDNE 854 Query: 454 LEHQQHMEGPSLIHVGTNTE-DVNEIAKVQEQLKQELNDEIKDVN-VKDLIEKLKSAEEQ 511 + ++ I N E +++E+ K + L+QE +D+ +VN +K E L+ ++ Sbjct: 855 NKDKEIERLKEEIEKLKNHEMNLDELEKEIKSLEQENDDD--EVNYLKKETEDLEKMAKE 912 Query: 512 ITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKV 571 + N++I K + ++ ++L ++ Q + + ++ L E LS+++ Sbjct: 913 VIFRNEKIQLEQK-IRDLEEENRLLIENYQNGHEE-ENLDSLEAQMTELMEMNQKLSREL 970 Query: 572 AELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELH 631 E+ +K N V+ E++ K+ + + T SLL +Q DL + + Sbjct: 971 DEVISKKENESSIEVEELKNAFTEANKQKEQVLKQY--NTLKATYSLLLTQYNDLKDQNN 1028 Query: 632 ---ILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLD 688 + + + E++ + +L++ E+K ++ + + ++L + N + Sbjct: 1029 FEKVTETETSEIQSLKEENEKLKAYNKSLELKFMNDSDNVRFAHEETEKLKQKVTNYEEK 1088 Query: 689 KEQLYGTIKDLENDKEDIMNKLQNYIQENMD---LTDKLEKMSAEK--ISELLAKINHEE 743 + L K+ E +++ + KL+ +I++ D L +K++ EK + + L K+N + Sbjct: 1089 IKTLEKEKKEHETEEQRLSGKLKEFIKQEEDFGVLLGNYKKLNEEKTNLEKSLNKLNDDL 1148 Query: 744 QSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIA----VMEDRRYSLERKA 799 Q + + ++ + I N E+E+S Y+ + +A ++++ SL+++ Sbjct: 1149 QK-------VTKENEKNKIIISNRETEISMYQHANTAQQNDLARENQQLQNQVTSLQKEV 1201 Query: 800 DQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILL 859 L + Q + + + ED + A + D + + + E E +K + L Sbjct: 1202 TSLQDKVTSLQTSNGDNSDAEDTINGLEAEITDLQQKFDNLTEDFEEEKSSHEKDVEELS 1261 Query: 860 EENQNLQISLSDMQQHYNALVEKANRTD-----LAESESTK----YQTQLR-DLESNLKR 909 + + L + + L KA++ L S+S+K Y ++ DLE + Sbjct: 1262 QTIEGLNKLCEEQHNTISQLTLKASQLQSEIDQLKPSDSSKPKPNYSVFVKLDLEKPEQP 1321 Query: 910 ITHEHQTLIVQKKKEIEDLEIEF-------NTQIESAIRDKKVLNEKYEKNIEYVTQLEA 962 +E + L Q ++E ++ E E N + E D ++L + ++ +++L+ Sbjct: 1322 NFNEEENLNEQNEEENKEEEEENKEEEENQNNEEEDDDNDNEMLMYQIQEQSREISKLKK 1381 Query: 963 QLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKD 1022 QL + + + EN + + EL +++ + D ++ + ++ + + Sbjct: 1382 QLNKLEKDKENADAAFKTAMDRVHELEEENTLMKHKIDSDGVKEDKPSLEEMKGKIDLLE 1441 Query: 1023 EEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQ 1082 E L Q++++ + + +D+ + + +++ + E++++ ++L D+K E+L+ Sbjct: 1442 YENSKLQQQVSSQPSTPVQQKNDFAENIEE---QIQQKDSEIEKLKEELADAK---EDLK 1495 Query: 1083 ILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXL 1142 + + DD T LT + K E +E + N ++ L Sbjct: 1496 YALAKLDDA-----NTSLTLNSSQTKDEE---EDDLESLKSQVNELEEQRDFYIKKSENL 1547 Query: 1143 KVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQIN----Q 1198 + ++ +E ++ + + Q + T K L+T+N L ++QI+ Q Sbjct: 1548 E-EKVKELTRKVTNFKPQIEETKTPKSNIEDKYQNLQTVNKGLAEEISAKEKQIDLLNSQ 1606 Query: 1199 LKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHL-AQREADFQ-KTEHE 1256 +K+K EQ+ +N++ ++ + ++ + + Q E+A ++ +RE D K + Sbjct: 1607 IKNKEEQIK-QNESEINKLFVEKNDLKIKLQQSSDELAAFKRERSEVKREKDEAVKKCQD 1665 Query: 1257 LRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADV 1316 L L+ YEQ D +Q + E K+ EQ ++ +D + LQ++ ++ Sbjct: 1666 LEKVLAV---SYEQD-DKIQE-LERENQKL--NEQYLFAADQCKDSNKQRDELQKENKEL 1718 Query: 1317 INQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQ 1376 I +I L +++ + + +QS +Q+QE ++ Q Sbjct: 1719 IEKINNLENDLLQAEKELDELTDEKEKLEEELSQAKKDLSQSKRQLQESK-----DDLFQ 1773 Query: 1377 LKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFEN 1436 +KK + D + +L ++E EI ++ E L ++ + Sbjct: 1774 IKKQMAEKERTISEQSVSIEDLGNQNDKLNEEIE----EIQKEKDENEEKLKDLQEKLKI 1829 Query: 1437 VRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESE--IERVKLIEELNVK 1494 + + + + L ++++ L + + E + E++ E+V++++ +K Sbjct: 1830 AQSKADSLKSQNNQLIKDRDNLQNQLNEFLLDGGKIDEKLVSENKQLAEKVQILQAHAIK 1889 Query: 1495 ITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKI 1554 E S AE + ALE +V Q E+ N+E+ L ++R+ S Sbjct: 1890 NIEGGSRVSAKAEEDPALERKVESLQVSLDGANKQIQELQKKNNELNELNGVLRSKLSNA 1949 Query: 1555 QK 1556 K Sbjct: 1950 IK 1951 Score = 66.1 bits (154), Expect = 8e-09 Identities = 135/656 (20%), Positives = 289/656 (44%), Gaps = 65/656 (9%) Query: 229 EAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQEL---EQXXXXX 285 E E K+E++ ++ E+++ + N++L E S E SKL ++L E+ Sbjct: 1334 EEENKEEEEENKEEEENQNNEEEDDDNDNEMLMYQIQEQSREISKLKKQLNKLEKDKENA 1393 Query: 286 XXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIA-NMTELTKKIELLEHLNCQIRQ-TNK 343 + E + K +I+ G E ++ E+ KI+LLE+ N +++Q + Sbjct: 1394 DAAFKTAMDRVHELEEENTLMKHKIDSDGVKEDKPSLEEMKGKIDLLEYENSKLQQQVSS 1453 Query: 344 ELENKLATMGTESKAVSSP-SKKGSPLISRKSGRNTASK-MKSPWSQL----SSETLNQD 397 + + ++ + +K S + K A + +K ++L +S TLN Sbjct: 1454 QPSTPVQQKNDFAENIEEQIQQKDSEIEKLKEELADAKEDLKYALAKLDDANTSLTLNSS 1513 Query: 398 TDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQ 457 K ++++ L+ + L + +++ I + + Q++ Sbjct: 1514 QTKDEEEDDLESLKSQVNELEEQ---RDFYIKKSENLEEKVKELTRKVTNFKPQIE---- 1566 Query: 458 QHMEGPSLIHVGTNTED-VNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLN 516 + P +N ED + V + L +E++ + K +++ L ++K+ EEQI Q Sbjct: 1567 -ETKTPK-----SNIEDKYQNLQTVNKGLAEEISAKEKQIDL--LNSQIKNKEEQIKQNE 1618 Query: 517 DEIDAANKNMIKVKSNHKLKLKQMQKTIDNF----SKVSDSNKEIVRLTEELHHL----- 567 EI NK ++ K++ K+KL+Q + F S+V E V+ ++L + Sbjct: 1619 SEI---NKLFVE-KNDLKIKLQQSSDELAAFKRERSEVKREKDEAVKKCQDLEKVLAVSY 1674 Query: 568 --SQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFD 625 K+ ELE E L + + + + +S+ + ++ EN + ++ I+ LE+ Sbjct: 1675 EQDDKIQELERENQKLNEQYL-FAADQCKDSNKQRDELQKEN--KELIEKINNLENDLLQ 1731 Query: 626 LVQELHILQQKYDEVEDKLA----DISQLQSDQVCSEIKSVHLEEQIDALSASKKELALV 681 +EL L + +++E++L+ D+SQ + S+ +++Q+ + E ++ Sbjct: 1732 AEKELDELTDEKEKLEEELSQAKKDLSQSKRQLQESKDDLFQIKKQMAEKERTISEQSVS 1791 Query: 682 IENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTD-KLEKMSAEKISELLAKIN 740 IE+L ++L I++++ +K++ KL++ +QE + + K + + ++ + + N Sbjct: 1792 IEDLGNQNDKLNEEIEEIQKEKDENEEKLKD-LQEKLKIAQSKADSLKSQNNQLIKDRDN 1850 Query: 741 HEEQ-SKIQTQFG-IDAK-IQERDLYIENIES-ELSKYK-----SRICRLEESIAVMEDR 791 + Q ++ G ID K + E E ++ + K SR+ E +E + Sbjct: 1851 LQNQLNEFLLDGGKIDEKLVSENKQLAEKVQILQAHAIKNIEGGSRVSAKAEEDPALERK 1910 Query: 792 RYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHE 847 SL+ D +QE QK +E L ++L+ + + EK LLE +++ Sbjct: 1911 VESLQVSLDGANKQIQELQKKNNELNELNGVLRSKLS-----NAIKEKTLLEFKND 1961 >UniRef50_A0EEL6 Cluster: Chromosome undetermined scaffold_91, whole genome shotgun sequence; n=2; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_91, whole genome shotgun sequence - Paramecium tetraurelia Length = 1894 Score = 141 bits (342), Expect = 1e-31 Identities = 225/1163 (19%), Positives = 500/1163 (42%), Gaps = 82/1163 (7%) Query: 470 TNTEDVNEIAKVQEQLKQEL-NDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIK 528 T+ + +I ++Q + K E N E++ N K+L ++L + +++ Q N+ + + Sbjct: 453 THIKAKQQIEELQNKFKLEFQNYELQLKNYKELYDQLSNTNKELVQKNENLQVEFNRQTQ 512 Query: 529 VKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEEL----HHLSQKVAELEEEKGNLQLH 584 + L+ Q+ I N ++ + KE + ++EL + ++ + ++E L Sbjct: 513 ISVT---ALQNKQQEILNLNEQTKKLKEDITKSQELKLTYNEQQTQINQFKKEIERLNQV 569 Query: 585 LVDYDSGRMIESDVYKKMIEMENLAETRLKAISL-LESQKFDLVQELHILQQKYDEVEDK 643 ++ S + + +IE TRL + + L SQ ++ +L++ ++DK Sbjct: 570 ILQNQSKSSQQEENLLTVIEQNKSEITRLHQLIIDLHSQIEQSDNQIQLLKEAEQIIKDK 629 Query: 644 LADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKL--DKEQLYGTIKDLEN 701 + S + SD+V +++ + ++I+ + ++ A+ +N++ ++Q TIK ++ Sbjct: 630 ITKDSLVYSDKV-KKLQEIIQNKEIEHSALEEEYKAIQSQNVEFYSQQQQDQDTIKLMKK 688 Query: 702 DKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERD 761 D + K Q ++ ++ KL + +I +L K E + + Q K+++ Sbjct: 689 D----LQKNQEQYEQKINEFIKLSERQLAEIKDLSEKYQQAENER-RNQDETITKLKKE- 742 Query: 762 LYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAY--SEYTIQ 819 ++ + K+ + ++S +++ + S ER +Q + E++K S+ +Q Sbjct: 743 -LLKQTNDHQKQVKTLQDQQKQSQEMLQQKLQSFERLNEQNQMIICEQKKLLHESQAQLQ 801 Query: 820 EDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEEN---QNLQISLSDMQQH- 875 + L N A+L ++ ++ + E EL + Q++L++ QN Q+ D QQ Sbjct: 802 KVNLENE-ALLQNNSESMQSMKEQYELLALELNQTKQVVLDQQELIQNQQLLHHDTQQEC 860 Query: 876 --------YNALVEKANRTDLAES--ESTKYQTQLR-DLESNLKR-----ITHEH--QTL 917 +V K N+++L ++ + QL+ +LE+ KR IT E QTL Sbjct: 861 YKFKKQIEQQDIVNKQNQSELGKTIQDQINLINQLKSNLEATEKRHIENKITAEQLSQTL 920 Query: 918 IVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQL-EAQLQEYKNNIENL-N 975 I + EI L E +TQ+ + I + + ++ Q E +L++ + N++ + N Sbjct: 921 ITTQS-EITQLRFE-STQLNNTIEQNSKTIQDLQSQLQIDQQQHEIELKQIQKNLDLVQN 978 Query: 976 MNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEI-IALNQKINN 1034 + +E + LEL K +Q+ Q Q + +QY +++ + +K E + L Q+IN Sbjct: 979 QSNQEKESIILEL-HKQIQEFQEQLQNQRDQYQHDVQQHQIQIKLNQERFDLVLQQEINQ 1037 Query: 1035 AQVSYMSMVSDYESKLAQFTTK---LENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQ 1091 +S E + F + LEN ++ + +K++ Q N+ L + EQ + Sbjct: 1038 INCQMEQQISTKEEEKQGFLDQIKALENKIVQLDQKNKEIYLQSQSNQNLYRQLIEQLET 1097 Query: 1092 IK-ELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEF 1150 ++ E + +L ++ + + + I + I S+ ++ ++ Q++ + Sbjct: 1098 LQQESQNEQLKWKDLLQQKDEKIRTIEINSKSE-IGKLNEQLIHTSERRAQIE-QDQIKL 1155 Query: 1151 IQERSVLQEQSAKLNTELQECYTKIIQLETL-NTELTGHDVVNQEQINQLKSKLEQLNTE 1209 I++ + ++ KL +L++ +I ++ L N + ++ +N + I + ++ + Sbjct: 1156 IEQEQITNQELQKLKEQLEQKQNEIDSIDKLLNERVLDNEELNGKLI-LVSKEMSLYKDQ 1214 Query: 1210 NDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYE 1269 N +L S +++ S S+ +++ F+I +E DF ++L+ Q+ FE + Sbjct: 1215 NKDLQSQISQQSESNSNTINELKFKI----------KEQDF--LINQLQSQVKDFECQMN 1262 Query: 1270 QLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIED 1329 L V +++ NK +++ N+L + LQ + D++ QI IL+ EI + Sbjct: 1263 LQLSEVILQSKDLVNK--KQQELDISSNELTQLKNQFIKLQNENDDLLKQITILQ-EINN 1319 Query: 1330 EKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNI-NEENAQLKKSSXXXXXXX 1388 K + NQ KQ + ++LN+ Q+ + Sbjct: 1320 NKDIQINDFENQVTKLHEQVNTINNYNQ-LKQEELDNVLNLLKNREQQIADQNELINNLQ 1378 Query: 1389 XXXXXRVNDAEAKVLELTH---QLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYE 1445 + D K+ L Q + SE+ Q + + + +E + L E Sbjct: 1379 ILQVKQEQDYNEKLNNLNQVSMQSSSEQSELKQIVEQVQMEKEKITEELLKKNENLKEIV 1438 Query: 1446 KRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQV 1505 K + + +L+ ++ E E Q +S++ ++L EEL + + E N ++ Sbjct: 1439 KNQQTTCQQLNEQLSSKDTELQEQGILIE--QYQSQV--LQLNEELTLIMDEKSQQNLKI 1494 Query: 1506 AELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTK 1565 +L +E+ L+N ++E + + N + + ++ +S + Sbjct: 1495 HQLRTNIEKIQQDLEVKSIQLQNSDLESENQKQQFESQLNELGNQNKELFVRLSELQEEN 1554 Query: 1566 QGRDEQLDNTMNKELLDAVPRAE 1588 EQ+ N+ L E Sbjct: 1555 STLIEQVRKRENEYRLKVFEMGE 1577 Score = 135 bits (326), Expect = 1e-29 Identities = 282/1444 (19%), Positives = 604/1444 (41%), Gaps = 120/1444 (8%) Query: 92 ESLANTLKQKEILME-KIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSN- 149 E L N K + E ++K YKEL + S T VT L N Sbjct: 462 EELQNKFKLEFQNYELQLKNYKELYDQLSNTNKELVQKNENLQVEFNRQTQISVTALQNK 521 Query: 150 -----TIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXX 204 + E+ L K + ++ T + Q +IN+ + IE N+ Sbjct: 522 QQEILNLNEQTKKLKEDITKSQELKLTYNEQQTQINQFKKEIERLNQVILQNQSKSSQQE 581 Query: 205 XXXXXXXEDTKQQMTKMQENFIAMEA--EWKDEKQRLLKDIES--KD-VRISSLEEANKL 259 E K ++T++ + I + + E D + +LLK+ E KD + SL ++K+ Sbjct: 582 ENLLTVIEQNKSEITRLHQLIIDLHSQIEQSDNQIQLLKEAEQIIKDKITKDSLVYSDKV 641 Query: 260 --LEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLE 317 L+ +EHS L +E + + +I+ ++ + +E+ + Sbjct: 642 KKLQEIIQNKEIEHSALEEEYKAIQSQNVEFYSQQQQ-DQDTIKLMKKDLQKNQEQYEQK 700 Query: 318 IANMTELTKK-IELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGR 376 I +L+++ + ++ L+ + +Q E N+ T+ K + + + + Sbjct: 701 INEFIKLSERQLAEIKDLSEKYQQAENERRNQDETITKLKKELLKQTNDHQKQVKTLQDQ 760 Query: 377 NTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVI---SEKDT 433 S+ S E LN+ I + + E Q L K ++ E ++ SE Sbjct: 761 QKQSQEMLQQKLQSFERLNEQNQMIICEQKKLLHESQAQ-LQKVNLENEALLQNNSESMQ 819 Query: 434 XXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEI 493 + Q+ L+ Q+ ++ L+H T E K ++Q++Q+ D + Sbjct: 820 SMKEQYELLALELNQTKQVVLDQQELIQNQQLLHHDTQ----QECYKFKKQIEQQ--DIV 873 Query: 494 KDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKT-IDNFSKVSD 552 N +L + ++ I QL ++A K I+ +K+ +Q+ +T I S+++ Sbjct: 874 NKQNQSELGKTIQDQINLINQLKSNLEATEKRHIE----NKITAEQLSQTLITTQSEITQ 929 Query: 553 SNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETR 612 E +L + S+ + +L+ + LQ +D + + K + ++N + Sbjct: 930 LRFESTQLNNTIEQNSKTIQDLQSQ---LQ---IDQQQHEIELKQIQKNLDLVQNQSNQE 983 Query: 613 LKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSD-QVCSEIKSVHLEEQIDAL 671 ++I L ++ QE LQ + D+ + D+ Q Q ++ E + L+++I+ + Sbjct: 984 KESIILELHKQIQEFQEQ--LQNQRDQYQH---DVQQHQIQIKLNQERFDLVLQQEINQI 1038 Query: 672 SASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEK 731 + ++ I + +K+ IK LEN K+ Q+N ++ L+ S + Sbjct: 1039 NCQMEQQ---ISTKEEEKQGFLDQIKALEN-------KIVQLDQKNKEIY--LQSQSNQN 1086 Query: 732 I-SELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMED 790 + +L+ ++ +Q Q +Q++D I IE KS I +L E + + Sbjct: 1087 LYRQLIEQLETLQQESQNEQLKWKDLLQQKDEKIRTIEINS---KSEIGKLNEQLIHTSE 1143 Query: 791 RRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKE 850 RR +E+ DQ+ ++++Q E +++L + + D+++ +++L+ E N + Sbjct: 1144 RRAQIEQ--DQI-KLIEQEQITNQELQKLKEQLEQKQNEIDSIDKLLNERVLDNEELNGK 1200 Query: 851 L---QKKNQILLEENQNLQISLSDMQQ-HYNALVEKANRTDLAESESTKYQTQLRDLESN 906 L K+ + ++N++LQ +S + + N + E + + + Q+Q++D E Sbjct: 1201 LILVSKEMSLYKDQNKDLQSQISQQSESNSNTINELKFKIKEQDFLINQLQSQVKDFECQ 1260 Query: 907 LKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQE 966 + E +I+Q K + + E + + K + +N + + Q+ LQE Sbjct: 1261 MNLQLSE---VILQSKDLVNKKQQELDISSNELTQLKNQFIKLQNENDDLLKQITI-LQE 1316 Query: 967 YKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEII 1026 NN + ++N ++ H Q + + +Q E++ + LLK ++++I Sbjct: 1317 INNNKDI------QINDFENQVTKLHEQVNTINNYNQLKQ--EELDNVLNLLKNREQQIA 1368 Query: 1027 ALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVR 1086 N+ INN Q+ + DY KL N+ + + S + + KQ E++Q+ Sbjct: 1369 DQNELINNLQILQVKQEQDYNE-------KLNNLNQVSMQSSSEQSELKQIVEQVQM--- 1418 Query: 1087 EQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSD-DANNVDXXXXXXXXXXXXLKVQ 1145 E++ +EL + + I K + E +S D + L++ Sbjct: 1419 EKEKITEELLKKNENLK-EIVKNQQTTCQQLNEQLSSKDTELQEQGILIEQYQSQVLQLN 1477 Query: 1146 EEEEFIQERSVLQEQSAKLNTELQECYTKIIQ-LETLNTELTGHDVVNQEQINQLKSKLE 1204 EE I + +Q+ K++ +L+ KI Q LE + +L D+ ++ Q Q +S+L Sbjct: 1478 EELTLIMDEK--SQQNLKIH-QLRTNIEKIQQDLEVKSIQLQNSDLESENQKQQFESQLN 1534 Query: 1205 QLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAF 1264 +L +N L ++EL+ S+ ++Q + +RE +++ E+ + + F Sbjct: 1535 ELGNQNKELFVRLSELQEENSTLIEQ------------VRKRENEYRLKVFEMG-EKNRF 1581 Query: 1265 ESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQI-EIL 1323 E++ + ++ + QE + V+ E V + ++++++ + L + Q +Y+ +I Q+ L Sbjct: 1582 ENEEQNKINQILQ--QELSISEVSEENVINALSQIKNEFQELLDKQSQYSTLIFQLYSEL 1639 Query: 1324 RSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINE--ENAQLKKSS 1381 ++ E+E V D + ++ + + ++ I E + Q K+SS Sbjct: 1640 LTDDEEEDVEKQIQVISNQMVGLIDVRDKYKKIENEFEGEGDILVKIKELKLSEQKKQSS 1699 Query: 1382 XXXXXXXXXXXXRVNDA---EAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVR 1438 ++ D E + ++ S + ++ + ++ E +N Sbjct: 1700 NSQDIKSIEAYSQLLDGLMQEFLHNRVNLTMQSMKSLLTEQQRQNVNEYRKKIGELQNKL 1759 Query: 1439 QQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITES 1498 Q + +K I+D + + I+ K + A +YE K + V+ I+E+ ++ + Sbjct: 1760 LQAEKQQKCIDDTKFNLQQYQQIVD-KSEQKAMYYEMECK----KLVQQIQEMKQRMPQR 1814 Query: 1499 VSLN 1502 +SLN Sbjct: 1815 ISLN 1818 Score = 128 bits (309), Expect = 1e-27 Identities = 232/1195 (19%), Positives = 489/1195 (40%), Gaps = 94/1195 (7%) Query: 446 DTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQL-KQELNDEIKDVNVKDLIEK 504 D+L QL+ Q++ + N++ ++ +A+++ QL K E E + V +K L + Sbjct: 136 DSLAVQLEKIKQENDTLRKRVSDNINSQSLSNLAQLKMQLQKAEKKAESRKVCIKKLYQL 195 Query: 505 LKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEEL 564 L +E+++ E+ + K K + K +L ++ + NKE + T E Sbjct: 196 LDKSEKEL-----ELYKSGKKSAKTSFSKKNELNEI------LNGTYPKNKENIPDTYEP 244 Query: 565 HHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKF 624 LS + +++++ N + + + + +DV E NL LK+ L+ QK Sbjct: 245 MLLSL-IKDIDQK--NYEA-IENLSKNNSLNTDVEN---EKNNLISNSLKSFKLMCEQKE 297 Query: 625 DLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSV-HLEEQIDALSASKKELALVIE 683 ++++ + + ++ K +I Q+ + +++ LE I + ++ Sbjct: 298 EILKYSAQICENNQDLWKKFLEIDLTCQKQISTLRQAISELETNIKSYYQYLNKIGHNSA 357 Query: 684 NLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEE 743 D Q G I D + ++Q I + + ++ + L I + + Sbjct: 358 QKFQDAYQFQGVIGDSIAKWLKQLGEIQEIINQRESEQYEFQQFQETLVMRLKEIIQNNK 417 Query: 744 QSKIQTQF-GIDAKIQERDLYIENIESELSKYKSRICRLEESIAVME-DRRYSLERKADQ 801 Q F G+ I ER L+ ++ E L + ++ + E ++ LE + + Sbjct: 418 IVHKQNDFKGLLDAINER-LFNQSEEILLINKELNNTHIKAKQQIEELQNKFKLEFQNYE 476 Query: 802 LGSYLQEKQKAYSEYTIQEDELVNRLAVL-MDHDRVVEKQLLEIEHENKELQKKNQIL-- 858 L L+ ++ Y + + ELV + L ++ +R + + ++++ +E+ N+ Sbjct: 477 L--QLKNYKELYDQLSNTNKELVQKNENLQVEFNRQTQISVTALQNKQQEILNLNEQTKK 534 Query: 859 ----LEENQNLQISLSDMQQHYNAL---VEKANRTDLAESESTKYQTQ--LRDLESNLKR 909 + ++Q L+++ ++ Q N +E+ N+ L + Q + L +E N Sbjct: 535 LKEDITKSQELKLTYNEQQTQINQFKKEIERLNQVILQNQSKSSQQEENLLTVIEQNKSE 594 Query: 910 ITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKN 969 IT HQ LI+ +IE + + QI+ ++++ +K K+ + +LQE Sbjct: 595 ITRLHQ-LIIDLHSQIE----QSDNQIQLLKEAEQIIKDKITKDSLVYSDKVKKLQEIIQ 649 Query: 970 NIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALN 1029 N E + +EE K ++ + QQ Q D + ++ K +QK E I L+ Sbjct: 650 NKEIEHSALEEEYKA-IQSQNVEFYSQQQQDQDTIKLMKKDLQKNQEQYEQKINEFIKLS 708 Query: 1030 QKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLL-DSKQHNEELQILVREQ 1088 ++ ++ + D K Q + N +E + ++ K+LL + H ++++ L ++Q Sbjct: 709 ER-------QLAEIKDLSEKYQQAENERRNQDETITKLKKELLKQTNDHQKQVKTL-QDQ 760 Query: 1089 DDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEE 1148 Q +E+ + KL + + MII + + + + +Q Sbjct: 761 QKQSQEMLQQKLQSFERLNEQNQMIICEQKKLLHESQAQLQKVNLENEAL-----LQNNS 815 Query: 1149 EFIQERSVLQEQSAKLNTELQECYTKIIQLETL--NTELTGHDVVNQEQINQLKSKLEQL 1206 E +Q ++EQ L EL + ++ + L N +L HD Q++ + K ++EQ Sbjct: 816 ESMQS---MKEQYELLALELNQTKQVVLDQQELIQNQQLLHHDT--QQECYKFKKQIEQQ 870 Query: 1207 NTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFES 1266 + N S + + + ++Q + K+H+ + T +L L +S Sbjct: 871 DIVNKQNQSELGKTIQDQINLINQLKSNLEATEKRHIENKI-----TAEQLSQTLITTQS 925 Query: 1267 KYEQL-LDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRS 1325 + QL +S Q + E N + + LQ Q E L+ +Q+ V NQ + Sbjct: 926 EITQLRFESTQLNNTIEQNSKTIQDLQSQLQIDQQQHEIELKQIQKNLDLVQNQSNQEKE 985 Query: 1326 EIEDE-KVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSIL----NINEENAQLKKS 1380 I E D++ K QE+ L IN+ N Q+++ Sbjct: 986 SIILELHKQIQEFQEQLQNQRDQYQHDVQQHQIQIKLNQERFDLVLQQEINQINCQMEQQ 1045 Query: 1381 SXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQ 1440 ++ E K++ QL+ K+ EIY ++ Q ++ E ++Q+ Sbjct: 1046 ISTKEEEKQGFLDQIKALENKIV----QLDQKNKEIYLQSQSNQNLYRQLIEQLETLQQE 1101 Query: 1441 LVEYEKRIEDLTYEKESELAILRL-------KMHENANHYETMQKESEIERVKLIEELNV 1493 + + +DL +K+ ++ + + K++E H + + E +++KLIE+ + Sbjct: 1102 SQNEQLKWKDLLQQKDEKIRTIEINSKSEIGKLNEQLIHTSERRAQIEQDQIKLIEQEQI 1161 Query: 1494 KITESVSLNKQVAE-------LNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNM 1546 E L +Q+ + ++K L E V E+ L E+ D+ +LQ+ Sbjct: 1162 TNQELQKLKEQLEQKQNEIDSIDKLLNERVLDNEELNGKLILVSKEMSLYKDQNKDLQSQ 1221 Query: 1547 VRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDLAMYMLHQRDV 1601 + S ++ K + L N + ++ D + L L+ +L +D+ Sbjct: 1222 ISQQSESNSNTIN-ELKFKIKEQDFLINQLQSQVKDFECQMNLQLSEVILQSKDL 1275 Score = 128 bits (309), Expect = 1e-27 Identities = 239/1164 (20%), Positives = 527/1164 (45%), Gaps = 139/1164 (11%) Query: 498 VKDLIEKLKSAEEQITQ---LNDEIDAANKNMIKVK-SNHKLKLKQMQKTIDNFSKVSDS 553 +KD+ +K A E +++ LN +++ N+I + KL +Q ++ + +++ ++ Sbjct: 250 IKDIDQKNYEAIENLSKNNSLNTDVENEKNNLISNSLKSFKLMCEQKEEILKYSAQICEN 309 Query: 554 NKEI------VRLT--EELHHLSQKVAELEEE-KGNLQ-LHLVDYDSGRMIESDVYKKMI 603 N+++ + LT +++ L Q ++ELE K Q L+ + ++S + + D Y+ Sbjct: 310 NQDLWKKFLEIDLTCQKQISTLRQAISELETNIKSYYQYLNKIGHNSAQKFQ-DAYQFQG 368 Query: 604 EMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVH 663 + + LK + ++ +++ + Q ++ + ++ L ++ ++ K VH Sbjct: 369 VIGDSIAKWLKQLGEIQ----EIINQRESEQYEFQQFQETLV----MRLKEIIQNNKIVH 420 Query: 664 LEEQIDAL-SASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTD 722 + L A + L E + L ++L T + E++ NK + Q N +L Sbjct: 421 KQNDFKGLLDAINERLFNQSEEILLINKELNNTHIKAKQQIEELQNKFKLEFQ-NYELQL 479 Query: 723 KLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLE 782 K K +++S ++ + ++ +Q +F +I L +N + E+ + +L+ Sbjct: 480 KNYKELYDQLSNTNKELVQKNEN-LQVEFNRQTQISVTAL--QNKQQEILNLNEQTKKLK 536 Query: 783 ESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLL 842 E I ++ + + + Q+ + +E ++ ++ +Q ++ E+ LL Sbjct: 537 EDITKSQELKLTYNEQQTQINQFKKEIERL-NQVILQNQSKSSQQ----------EENLL 585 Query: 843 EIEHENK-ELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLR 901 + +NK E+ + +Q++++ + QI SD Q E+ + D +S Y +++ Sbjct: 586 TVIEQNKSEITRLHQLIIDLHS--QIEQSDNQIQLLKEAEQIIK-DKITKDSLVYSDKVK 642 Query: 902 DLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQ-------IESAIRDKKVLNEKYEKNI 954 L+ ++ EH L ++ K I+ +EF +Q I+ +D + E+YE+ I Sbjct: 643 KLQEIIQNKEIEHSAL-EEEYKAIQSQNVEFYSQQQQDQDTIKLMKKDLQKNQEQYEQKI 701 Query: 955 -EYVTQLEAQLQEYKN------NIENLNMNVEE-LNKMNLELID---------KHVQKQQ 997 E++ E QL E K+ EN N +E + K+ EL+ K +Q QQ Sbjct: 702 NEFIKLSERQLAEIKDLSEKYQQAENERRNQDETITKLKKELLKQTNDHQKQVKTLQDQQ 761 Query: 998 TQSPDYTEQYINEINKLNALLKQKDEEIIALNQKI-NNAQVSYMSMVSDYESKLAQFTTK 1056 QS + +Q + +LN ++++ II +K+ + +Q + + E+ L + Sbjct: 762 KQSQEMLQQKLQSFERLN----EQNQMIICEQKKLLHESQAQLQKVNLENEALLQNNSES 817 Query: 1057 LENMEEEMQRVSKQLLDSKQHNEELQILVREQD----DQIKELKETKLTFEMN--IPKTE 1110 +++M+E+ + ++ +L +KQ + Q L++ Q D +E + K E + K Sbjct: 818 MQSMKEQYELLALELNQTKQVVLDQQELIQNQQLLHHDTQQECYKFKKQIEQQDIVNKQN 877 Query: 1111 GMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQE 1170 + TI+ + N + K+ E+ Q Q + +L E + Sbjct: 878 QSELGKTIQDQINLINQLKSNLEATEKRHIENKITAEQ-LSQTLITTQSEITQLRFESTQ 936 Query: 1171 CYTKIIQLETLNTELTGHDVVNQEQINQLKSKLE--QLNTENDNLLSTVAELRSSISSAV 1228 I Q N++ T D+ +Q QI+Q + ++E Q+ D + + + + SI + Sbjct: 937 LNNTIEQ----NSK-TIQDLQSQLQIDQQQHEIELKQIQKNLDLVQNQSNQEKESIILEL 991 Query: 1229 DQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSV------QSSTQEE 1282 ++ E E + Q + D Q+ + ++++ F+ +Q ++ + Q ST+EE Sbjct: 992 HKQIQEFQEQLQNQRDQYQHDVQQHQIQIKLNQERFDLVLQQEINQINCQMEQQISTKEE 1051 Query: 1283 TNKIVTMEQVTSLQNKL-----QDKEEHLRNL--QEKYADVINQIEILRSEIEDEKVAFX 1335 K ++Q+ +L+NK+ ++KE +L++ Q Y +I Q+E L+ E ++E++ + Sbjct: 1052 -EKQGFLDQIKALENKIVQLDQKNKEIYLQSQSNQNLYRQLIEQLETLQQESQNEQLKWK 1110 Query: 1336 XXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRV 1395 + ++E ++ EQ +++ +E AQ+++ ++ Sbjct: 1111 DLLQQKDEKIRTIEINSKSE---IGKLNEQ-LIHTSERRAQIEQDQIKLIEQE-----QI 1161 Query: 1396 NDAEAKVLELTHQLELKDSEIY---QKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLT 1452 + E + +L QLE K +EI + +E + + N + V +++ Y+ + +DL Sbjct: 1162 TNQELQ--KLKEQLEQKQNEIDSIDKLLNERVLDNEELNGKLILVSKEMSLYKDQNKDLQ 1219 Query: 1453 YE--KESEL---AILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAE 1507 + ++SE I LK + Q +S+++ + ++N++++E + +K + Sbjct: 1220 SQISQQSESNSNTINELKFKIKEQDFLINQLQSQVKDFEC--QMNLQLSEVILQSKDL-- 1275 Query: 1508 LNKALEEEVAKTNEMQTALENQEIEIVTLNDE----ITNLQ----------NMVRASSSK 1553 +NK +E +NE+ T L+NQ I++ ND+ IT LQ N +K Sbjct: 1276 VNKKQQELDISSNEL-TQLKNQFIKLQNENDDLLKQITILQEINNNKDIQINDFENQVTK 1334 Query: 1554 IQKHVSFASDTKQGRDEQLDNTMN 1577 + + V+ ++ Q + E+LDN +N Sbjct: 1335 LHEQVNTINNYNQLKQEELDNVLN 1358 Score = 127 bits (307), Expect = 2e-27 Identities = 237/1248 (18%), Positives = 538/1248 (43%), Gaps = 94/1248 (7%) Query: 369 LISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDK-EYV 427 L+ K NT K K +L ++ + + ++ +L + + NK+LV K E + Sbjct: 444 LLINKELNNTHIKAKQQIEELQNKFKLEFQNYELQLKNYKELYDQLSNTNKELVQKNENL 503 Query: 428 ISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSL-----IHVGTNTEDVNEIAKVQ 482 E + K I L + ++ E + + +N+ K Sbjct: 504 QVEFNRQTQISVTALQNKQQEILNLNEQTKKLKEDITKSQELKLTYNEQQTQINQFKKEI 563 Query: 483 EQLKQEL--NDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQM 540 E+L Q + N ++L+ ++ + +IT+L+ I + + I+ N LK+ Sbjct: 564 ERLNQVILQNQSKSSQQEENLLTVIEQNKSEITRLHQLIIDLH-SQIEQSDNQIQLLKEA 622 Query: 541 QKTI-DNFSKVS-DSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDV 598 ++ I D +K S + ++ +L E + + + + LEEE +Q V++ S + + D Sbjct: 623 EQIIKDKITKDSLVYSDKVKKLQEIIQNKEIEHSALEEEYKAIQSQNVEFYSQQQQDQDT 682 Query: 599 YKKMIE--MENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVC 656 K M + +N + K ++ + L E+ L +KY + E++ + + + Sbjct: 683 IKLMKKDLQKNQEQYEQKINEFIKLSERQLA-EIKDLSEKYQQAENERRNQDETITKLKK 741 Query: 657 SEIKSVH-LEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQ 715 +K + ++Q+ L +K+ +++ E+L + + +++ ++++ Q +Q Sbjct: 742 ELLKQTNDHQKQVKTLQDQQKQSQEMLQQKLQSFERLNEQNQMIICEQKKLLHESQAQLQ 801 Query: 716 E-NMD----LTDKLEKMSAEKIS-ELLA-KINHEEQSKIQTQFGIDAKIQERDLYIENIE 768 + N++ L + E M + K ELLA ++N +Q + Q IQ + L + + Sbjct: 802 KVNLENEALLQNNSESMQSMKEQYELLALELNQTKQVVLDQQ----ELIQNQQLLHHDTQ 857 Query: 769 SELSKYKSRICRLEESIAVMEDRRYSLERKA-------DQLGSYLQEKQKAYSEYTIQED 821 E K+K +I E+ V + + L + +QL S L+ +K + E I + Sbjct: 858 QECYKFKKQI---EQQDIVNKQNQSELGKTIQDQINLINQLKSNLEATEKRHIENKITAE 914 Query: 822 ELVNRLAVLMDHD---RVVEKQLLE-IEHENKELQKKNQILLEENQNLQISLSDMQQHYN 877 +L L R QL IE +K +Q L + Q +I L +Q++ + Sbjct: 915 QLSQTLITTQSEITQLRFESTQLNNTIEQNSKTIQDLQSQLQIDQQQHEIELKQIQKNLD 974 Query: 878 ALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIE 937 + ++N+ ES + Q+++ + L+ ++Q + Q + +I+ + F+ ++ Sbjct: 975 LVQNQSNQEK--ESIILELHKQIQEFQEQLQNQRDQYQHDVQQHQIQIKLNQERFDLVLQ 1032 Query: 938 SAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELI-----DKH 992 I +N + E+ I + E + Q + + I+ L + +L++ N E+ +++ Sbjct: 1033 QEINQ---INCQMEQQI---STKEEEKQGFLDQIKALENKIVQLDQKNKEIYLQSQSNQN 1086 Query: 993 VQKQQTQSPDYTEQYI-NEINKLNALLKQKDEEI--IALNQKINNAQVSYMSM-VSDYES 1048 + +Q + + +Q NE K LL+QKDE+I I +N K +++ + S+ + Sbjct: 1087 LYRQLIEQLETLQQESQNEQLKWKDLLQQKDEKIRTIEINSKSEIGKLNEQLIHTSERRA 1146 Query: 1049 KLAQFTTKLENMEE----EMQRVSKQLLDSKQHNEELQILVREQDDQIKEL--KETKLTF 1102 ++ Q KL E+ E+Q++ +QL + + + L+ E+ +EL K ++ Sbjct: 1147 QIEQDQIKLIEQEQITNQELQKLKEQLEQKQNEIDSIDKLLNERVLDNEELNGKLILVSK 1206 Query: 1103 EMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQE-RSVLQEQS 1161 EM++ K + + S I S+ +N K++E++ I + +S +++ Sbjct: 1207 EMSLYKDQNKDLQSQISQQSESNSNT--------INELKFKIKEQDFLINQLQSQVKDFE 1258 Query: 1162 AKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVA--- 1218 ++N +L E I+Q + L + ++ ++ QLK++ +L END+LL + Sbjct: 1259 CQMNLQLSEV---ILQSKDLVNKKQQELDISSNELTQLKNQFIKLQNENDDLLKQITILQ 1315 Query: 1219 ELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSS 1278 E+ ++ ++ ++ +L +Q + K E EL L+ +++ +Q+ D + Sbjct: 1316 EINNNKDIQINDFENQVTKLHEQVNTINNYNQLKQE-ELDNVLNLLKNREQQIADQNELI 1374 Query: 1279 TQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXX 1338 + ++ + N L + Q + ++ Q+++ + +I +E + Sbjct: 1375 NNLQILQVKQEQDYNEKLNNLNQVSMQSSSEQSELKQIVEQVQMEKEKITEELLKKNENL 1434 Query: 1339 XXXXXXXXXXXXDLRTENQSYK-QMQEQSIL--NINEENAQLKKSSXXXXXXXXXXXXRV 1395 L + S ++QEQ IL + QL + ++ Sbjct: 1435 KEIVKNQQTTCQQLNEQLSSKDTELQEQGILIEQYQSQVLQLNEELTLIMDEKSQQNLKI 1494 Query: 1396 NDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEK 1455 + + ++ LE+K ++ E Q + + Q E R+ +L E Sbjct: 1495 HQLRTNIEKIQQDLEVKSIQLQNSDLESENQKQQFESQLNELGNQNKELFVRLSELQEEN 1554 Query: 1456 ESELAILR-------LKMHE--NANHYETMQKESEIERVKLIEELNVKITESVSLNKQVA 1506 + + +R LK+ E N +E +++++I ++ L +EL++ ++ ++ Sbjct: 1555 STLIEQVRKRENEYRLKVFEMGEKNRFEN-EEQNKINQI-LQQELSISEVSEENVINALS 1612 Query: 1507 ELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKI 1554 ++ +E + K ++ T + E++T +DE +++ ++ S+++ Sbjct: 1613 QIKNEFQELLDKQSQYSTLIFQLYSELLT-DDEEEDVEKQIQVISNQM 1659 Score = 117 bits (281), Expect = 3e-24 Identities = 213/1147 (18%), Positives = 485/1147 (42%), Gaps = 101/1147 (8%) Query: 500 DLIEKLKSAEEQITQLNDEIDAANKNMI-KVKSNHKLKLKQMQKTIDNFSKVSDSNKEIV 558 D++E S Q+ ++ E D K + + S L Q++ + K ++S K + Sbjct: 130 DVLESADSLAVQLEKIKQENDTLRKRVSDNINSQSLSNLAQLKMQLQKAEKKAESRKVCI 189 Query: 559 RLTEELHHLSQKVAELEEE-KGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETR----L 613 + +L S+K EL + K + + + I + Y K EN+ +T L Sbjct: 190 KKLYQLLDKSEKELELYKSGKKSAKTSFSKKNELNEILNGTYPK--NKENIPDTYEPMLL 247 Query: 614 KAISLLESQKFDLVQELHILQQKYDEVEDKLADI--SQLQSDQVCSEIKSVHLEEQIDAL 671 I ++ + ++ ++ L +VE++ ++ + L+S ++ E K L+ Sbjct: 248 SLIKDIDQKNYEAIENLSKNNSLNTDVENEKNNLISNSLKSFKLMCEQKEEILKYSAQIC 307 Query: 672 SASKKELALVIE-NLKLDKE--QLYGTIKDLENDKEDI---MNKLQNYIQENMDLTDKLE 725 ++ +E +L K+ L I +LE + + +NK+ + + + + Sbjct: 308 ENNQDLWKKFLEIDLTCQKQISTLRQAISELETNIKSYYQYLNKIGHNSAQKFQDAYQFQ 367 Query: 726 KMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESI 785 + + I++ L ++ E Q I + + Q+ + E+ + + + + Sbjct: 368 GVIGDSIAKWLKQLG-EIQEIINQRESEQYEFQQFQETLVMRLKEIIQNNKIVHKQNDFK 426 Query: 786 AVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIE 845 +++ L +++++ +E + + Q +EL N+ + + E QL + Sbjct: 427 GLLDAINERLFNQSEEILLINKELNNTHIKAKQQIEELQNKFKLEFQN---YELQLKNYK 483 Query: 846 HENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLES 905 +L N+ L+++N+NLQ+ + Q ++ + L +E TK + Sbjct: 484 ELYDQLSNTNKELVQKNENLQVEFNRQTQISVTALQNKQQEILNLNEQTKKLKEDITKSQ 543 Query: 906 NLKRITHEHQTLIVQKKKEIEDL-EIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQL 964 LK +E QT I Q KKEIE L ++ Q +S+ +++ +L E+N +T+L + Sbjct: 544 ELKLTYNEQQTQINQFKKEIERLNQVILQNQSKSSQQEENLLT-VIEQNKSEITRLHQLI 602 Query: 965 QEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEE 1024 + + IE + ++ L + ++I + K Y +++ KL +++ K+ E Sbjct: 603 IDLHSQIEQSDNQIQLLKEAE-QIIKDKITKDSL-------VYSDKVKKLQEIIQNKEIE 654 Query: 1025 IIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQIL 1084 AL ++ Q + S + Q T KL M++++Q+ + +Q+ +++ Sbjct: 655 HSALEEEYKAIQSQNVEFYSQQQQD--QDTIKL--MKKDLQK------NQEQYEQKINEF 704 Query: 1085 VREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKV 1144 ++ + Q+ E+K+ +S + ++ N D + Sbjct: 705 IKLSERQLAEIKD----------------LSEKYQQAENERRNQDETITKLKKEL----L 744 Query: 1145 QEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLE 1204 ++ + ++ LQ+Q + LQ+ K+ E LN + ++ +++ +++L+ Sbjct: 745 KQTNDHQKQVKTLQDQQKQSQEMLQQ---KLQSFERLNEQNQMIICEQKKLLHESQAQLQ 801 Query: 1205 QLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQRE--ADFQKTEHELRVQLS 1262 ++N EN+ LL +E S+ + E+ + + L Q+E + Q H+ + + Sbjct: 802 KVNLENEALLQNNSESMQSMKEQYELLALELNQTKQVVLDQQELIQNQQLLHHDTQQECY 861 Query: 1263 AFESKYEQLLDSVQSSTQEETNKIV--TMEQVTSLQNKLQDKEE-HLRN--LQEKYADVI 1317 F+ + EQ D V Q E K + + + L++ L+ E+ H+ N E+ + + Sbjct: 862 KFKKQIEQ-QDIVNKQNQSELGKTIQDQINLINQLKSNLEATEKRHIENKITAEQLSQTL 920 Query: 1318 NQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSY----KQMQEQSILNINEE 1373 + +++ E L+ + Q + KQ+Q+ L N+ Sbjct: 921 ITTQSEITQLRFESTQLNNTIEQNSKTIQDLQSQLQIDQQQHEIELKQIQKNLDLVQNQS 980 Query: 1374 NAQLKKSSXXXXXXXXXXXXRVNDAEAKVLE--LTHQLELK------DSEIYQKTHEYTI 1425 N + + ++ + + HQ+++K D + Q+ ++ Sbjct: 981 NQEKESIILELHKQIQEFQEQLQNQRDQYQHDVQQHQIQIKLNQERFDLVLQQEINQINC 1040 Query: 1426 TLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHY-------ETMQK 1478 + Q+ E +Q ++ K +E+ + + + + L+ N N Y ET+Q+ Sbjct: 1041 QMEQQISTKEEEKQGFLDQIKALENKIVQLDQKNKEIYLQSQSNQNLYRQLIEQLETLQQ 1100 Query: 1479 ESEIERVK---LIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVT 1535 ES+ E++K L+++ + KI ++ +N + +E+ K L E++ T+E + +E +I+++ Sbjct: 1101 ESQNEQLKWKDLLQQKDEKI-RTIEINSK-SEIGK-LNEQLIHTSERRAQIEQDQIKLIE 1157 Query: 1536 LNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDLAMYM 1595 ++ITN Q + + QK S K + LD N+EL + ++++Y Sbjct: 1158 -QEQITN-QELQKLKEQLEQKQNEIDSIDKLLNERVLD---NEELNGKLILVSKEMSLYK 1212 Query: 1596 LHQRDVR 1602 +D++ Sbjct: 1213 DQNKDLQ 1219 Score = 62.5 bits (145), Expect = 9e-08 Identities = 103/523 (19%), Positives = 223/523 (42%), Gaps = 43/523 (8%) Query: 386 WSQLSSETLNQDTDKKINKNE-IAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXG 444 ++QL E L+ + N+ + IA +I +L V +E +EK Sbjct: 1345 YNQLKQEELDNVLNLLKNREQQIADQNELINNLQILQVKQEQDYNEKLNNLNQVSMQSSS 1404 Query: 445 KDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEI--KDVNVKDLI 502 + + + Q+ + Q E + + N E++ EI K Q+ Q+LN+++ KD +++ Sbjct: 1405 EQSELKQIVEQVQMEKEKITEELLKKN-ENLKEIVKNQQTTCQQLNEQLSSKDTELQEQG 1463 Query: 503 EKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSK-VSDSNKEIVRLT 561 ++ + Q+ QLN+E+ ++ KS LK+ Q++ I+ + + + ++ Sbjct: 1464 ILIEQYQSQVLQLNEELTL----IMDEKSQQNLKIHQLRTNIEKIQQDLEVKSIQLQNSD 1519 Query: 562 EELHHLSQKVAELEEEKGNLQLHL-VDYDSGRMIESDVYKKMIEMENLAETRLKAISLLE 620 E + Q+ E GN L V + S + +++ + EN E RLK + E Sbjct: 1520 LESENQKQQFESQLNELGNQNKELFVRLSELQEENSTLIEQVRKREN--EYRLKVFEMGE 1577 Query: 621 SQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELAL 680 +F+ ++ I Q E+ ++++S+ S+IK+ +E +D S + Sbjct: 1578 KNRFENEEQNKINQILQQELS--ISEVSEENVINALSQIKN-EFQELLDKQSQYSTLIFQ 1634 Query: 681 VIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISE--LLAK 738 + L D E+ +D+E + I N++ I D+ DK +K+ E E +L K Sbjct: 1635 LYSELLTDDEE-----EDVEKQIQVISNQMVGLI----DVRDKYKKIENEFEGEGDILVK 1685 Query: 739 INHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERK 798 I + S+ + Q I+ + Y + ++ + ++ R +L + Sbjct: 1686 IKELKLSEQKKQSSNSQDIKSIEAYSQLLDGLMQEFLHN--------------RVNLTMQ 1731 Query: 799 ADQLGSYLQEKQKA-YSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQI 857 + + S L E+Q+ +EY + EL N+L + ++ ++ + + K Q Sbjct: 1732 S--MKSLLTEQQRQNVNEYRKKIGELQNKLLQAEKQQKCIDDTKFNLQQYQQIVDKSEQK 1789 Query: 858 LLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQL 900 + + + +Q+ + ++ + DL + +S ++ + Sbjct: 1790 AMYYEMECKKLVQQIQEMKQRMPQRISLNDLDQDQSEQHSLNI 1832 >UniRef50_Q2NHV1 Cluster: Putative uncharacterized protein; n=1; Methanosphaera stadtmanae DSM 3091|Rep: Putative uncharacterized protein - Methanosphaera stadtmanae (strain DSM 3091) Length = 1104 Score = 141 bits (341), Expect = 2e-31 Identities = 203/981 (20%), Positives = 436/981 (44%), Gaps = 105/981 (10%) Query: 392 ETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQ 451 E +Q++ +N+ ++K E I++L + ++ ISE + + L + Sbjct: 98 EVESQNSGSSLNEMVLSKYENQIKALEDKIQTQKTTISELEEAANNSNDYLAEINRLKEE 157 Query: 452 ---LQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSA 508 LQ E Q + T ++ EI ++ QL E++ +D +K E++ Sbjct: 158 KSLLQSESSQTEVNQLKSIIEKQTVELKEIPILKNQLTMEVSS--RDQKIKKYEEEIDLL 215 Query: 509 EEQITQLNDEIDAANKNMIKVK---SNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELH 565 E++ + N+++ + +++I+ + S +KL++ Q +K + + S +K LT ++ Sbjct: 216 NEKLGE-NEDVSSIKEDLIQKEDEISKYKLEILQFEKQVAALKENSSEDKS-EDLTAQIT 273 Query: 566 HLSQKVAELEEEKGNLQLHLVDYDSGRM--IESDVYKKMIEMENLAETRLKAISLLESQK 623 L K+A LE E +L+ V D + + D+ KK E+ +L + + + Sbjct: 274 DLESKIAFLEHENNSLREGNVTSDKQGLDSLIEDITKKSNELIDLRSKYQRLQDTNKINE 333 Query: 624 FDLVQELHILQQKYDEVED-KLADISQLQSDQVCSEIKSVH--LEEQIDALSASKKELAL 680 F ++ EL K +E D K +D+S+ ++ SE K + L E+ LS S+ E+ L Sbjct: 334 FKII-ELENENAKLNESIDLKESDVSETVDLELISENKELKNTLLEKEQLLSQSENEVNL 392 Query: 681 VIENLKLDKEQLYGTIKDLENDKEDIM---NKLQNYIQENMDLTDKLEKM-SAEKISELL 736 + + ++ ++ + L +ED+ NKLQ+ + DL D + K+ S EK EL Sbjct: 393 LKNTILKNQTEVDDLSEKLAQSREDVTTLNNKLQDSQLKVGDLNDDVLKLKSLEKTIELK 452 Query: 737 -------------AKINHEEQSKIQTQF----GIDAKIQERDLYIENIESELSKYKSRIC 779 K N++ K Q + ++ E+DL I ++ S+ +S+I Sbjct: 453 DMDYSKLEDKYQQLKDNYDNLEKSQVDVDELSSLKEQVNEKDLNIRSLTSQNEASESKIA 512 Query: 780 RLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQE-----DELVNRLA----VL 830 LE+++ ++ L+ + D +K+ + T QE EL + A + Sbjct: 513 ELEKTLTTRDNEISELKSELDSFD--FSKKESEINNATNQEIKSIKKELYTKDAEFDKLK 570 Query: 831 MDHDRVVEKQLLEIEHENKELQK---KNQILLEENQNLQISLSDMQQHYNALVEKANRTD 887 +D++++ + +I N+ L K +N+ +L E + L+ SL N L ++ N + Sbjct: 571 LDYNQLRKNSSKQINELNEALDKFTNENEKILTEKKYLEDSLDSKNSLLNKLEQENNSLN 630 Query: 888 LAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLN 947 L + L+ +KR E L+ Q ++ D ++E + LN Sbjct: 631 LIIKDKDSNYNVLKKKFQEIKRNNEEQINLLKQDVQDKNDKIAALPQKLELKDIEISQLN 690 Query: 948 EKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELN---KMNLELIDKHVQKQQTQSPDYT 1004 + + + V +++ +N ++ +++LN N +ID+ ++ ++ + Sbjct: 691 KIVKSHENDVLSKNNEIKTLRNKVQESREVIKQLNDKLSENSVVIDEKIRSKEDEIFKLK 750 Query: 1005 EQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEM 1064 + + N +N +KDEEI L S++S K+ + T + ++ ++ Sbjct: 751 DNFKNSVN-------EKDEEISRLK-----------SLLSQRNYKIDELTENVGSLNHDL 792 Query: 1065 QRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMI--ISSTIEPMS 1122 + +S + D+K+ + + +++ +DD I + E I + E I + IE ++ Sbjct: 793 EVLSFKFEDNKEQFNKCEEIIQAKDDVISKKDELIEDINQQINRLENKIKLKNDDIEELN 852 Query: 1123 DDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLN 1182 DD + D ++EE + E + KLN +L + ++I + +TL Sbjct: 853 DDLSKKDTLIS---------NLKEE---------ISESNLKLN-KLDDLSSQIKENDTLI 893 Query: 1183 TELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQH 1242 +L + ++++ + + +L+T+ + ++ + EL + ++ ++E Q Sbjct: 894 EKLNDELALKEQEVQE---NVRELDTDKSH-ITELKELIERKNKDIEDHKKLLSEKNTQL 949 Query: 1243 LAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQE----ETNKIVTMEQVTSLQNK 1298 L + D + +EL V+ S + Y+Q + S+ + ++ +T +EQ++ L+ + Sbjct: 950 LEFK--DLKPRINELEVEKSDMMANYQQQITSLNADLEKAQLFKTENEKKIEQISQLKEQ 1007 Query: 1299 LQDKEEHLRNLQE--KYADVI 1317 L DK+ + + ++ KY DV+ Sbjct: 1008 LNDKDAQIASYEQYKKYFDVL 1028 Score = 135 bits (326), Expect = 1e-29 Identities = 229/1113 (20%), Positives = 504/1113 (45%), Gaps = 114/1113 (10%) Query: 493 IKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSD 552 +KDV ++L E +KS ++I L ++++ NK+ +KSN +K +Q +N + + Sbjct: 4 LKDVESEELRELVKSCFKEINTLKEQLNDENKD---IKSNKVVKNVLIQSESNNTNLQAK 60 Query: 553 SNKEIVRLTEELHHLSQKVAELEE-----EKGNLQLHLVD-YDSGRMIESDVYKKMIEME 606 N+ ++ ++ +L +K EL+E ++ +LQ+ V+ +SG + V K Sbjct: 61 INELTDKVHKQDTYLKEKELELQEMETRLKEKDLQIKEVESQNSGSSLNEMVLSKY---- 116 Query: 607 NLAETRLKAI-SLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLE 665 E ++KA+ +++QK + + L++ + D LA+I++L+ ++ S ++S + Sbjct: 117 ---ENQIKALEDKIQTQKTTISE----LEEAANNSNDYLAEINRLKEEK--SLLQSESSQ 167 Query: 666 EQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKL- 724 +++ L + ++ + ++ + + K QL +E D K++ Y +E L +KL Sbjct: 168 TEVNQLKSIIEKQTVELKEIPILKNQL-----TMEVSSRD--QKIKKYEEEIDLLNEKLG 220 Query: 725 EKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEES 784 E I E L + +E SK + + + + Q L + E + ++I LE Sbjct: 221 ENEDVSSIKEDLIQ-KEDEISKYKLEI-LQFEKQVAALKENSSEDKSEDLTAQITDLESK 278 Query: 785 IAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELV---NRLAVLMDHDRVVEKQL 841 IA +E SL + + S Q + T + +EL+ ++ L D +++ E ++ Sbjct: 279 IAFLEHENNSL--REGNVTSDKQGLDSLIEDITKKSNELIDLRSKYQRLQDTNKINEFKI 336 Query: 842 LEIEHENKELQ-----KKNQI-------LLEENQNLQISLSDMQQHYNALVEKANRTDLA 889 +E+E+EN +L K++ + L+ EN+ L+ +L + +Q L + N +L Sbjct: 337 IELENENAKLNESIDLKESDVSETVDLELISENKELKNTLLEKEQ---LLSQSENEVNLL 393 Query: 890 ESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEK 949 ++ K QT++ DL L + + TL +++D +++ + ++ K + Sbjct: 394 KNTILKNQTEVDDLSEKLAQSREDVTTL----NNKLQDSQLKVGDLNDDVLKLKSLEKTI 449 Query: 950 YEKNIEYVTQLEAQLQEYKNNIENL---NMNVEELNKMNLELIDKHVQKQQTQSPDYTEQ 1006 K+++Y ++LE + Q+ K+N +NL ++V+EL+ + ++ +K + + S + + Sbjct: 450 ELKDMDY-SKLEDKYQQLKDNYDNLEKSQVDVDELSSLKEQVNEKDLNIRSLTSQNEASE 508 Query: 1007 YINEINKLNALLKQKDEEIIALNQKIN----NAQVSYMSMVSDYESKLAQFTTKLENMEE 1062 ++I +L L +D EI L +++ + + S ++ ++ E K + ++ E Sbjct: 509 --SKIAELEKTLTTRDNEISELKSELDSFDFSKKESEINNATNQEIKSIKKELYTKDAEF 566 Query: 1063 EMQRVSKQLL---DSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIE 1119 + ++ L SKQ NE + L + ++ K L E K E ++ ++ + +E Sbjct: 567 DKLKLDYNQLRKNSSKQINELNEALDKFTNENEKILTEKKY-LEDSLDSKNSLL--NKLE 623 Query: 1120 PMSDDANNV----DXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKI 1175 ++ N + D +K EE+ + +Q+++ K+ Q+ K Sbjct: 624 QENNSLNLIIKDKDSNYNVLKKKFQEIKRNNEEQINLLKQDVQDKNDKIAALPQKLELKD 683 Query: 1176 IQLETLNTELTGH--DVVNQ-EQINQLKSKLEQ----LNTENDNLLSTVAELRSSISSAV 1228 I++ LN + H DV+++ +I L++K+++ + ND L + I S Sbjct: 684 IEISQLNKIVKSHENDVLSKNNEIKTLRNKVQESREVIKQLNDKLSENSVVIDEKIRSKE 743 Query: 1229 DQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQE-ETNKIV 1287 D+ F++ + +K + +++ + + L+ LS K ++L ++V S + E Sbjct: 744 DEI-FKLKDNFKNSVNEKDEEISR----LKSLLSQRNYKIDELTENVGSLNHDLEVLSFK 798 Query: 1288 ---TMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIE---DEKVAFXXXXXXX 1341 EQ + +Q K++ + E D+ QI L ++I+ D+ Sbjct: 799 FEDNKEQFNKCEEIIQAKDDVISKKDELIEDINQQINRLENKIKLKNDDIEELNDDLSKK 858 Query: 1342 XXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAE-- 1399 ++ N ++ + S I E + ++K + V + + Sbjct: 859 DTLISNLKEEISESNLKLNKLDDLS-SQIKENDTLIEKLNDELALKEQEVQENVRELDTD 917 Query: 1400 -AKVLELTHQLELKDSEIYQKTHEYTITLTQRND---EFENVRQQLVEYEKRIEDLTYEK 1455 + + EL +E K+ +I ++ L+++N EF++++ ++ E E D+ Sbjct: 918 KSHITELKELIERKNKDI----EDHKKLLSEKNTQLLEFKDLKPRINELEVEKSDMMANY 973 Query: 1456 ESELAILRLKMHENANHYETMQKESEIERV-KLIEELNVKITESVSLNKQVAELNKALEE 1514 + ++ L + E A ++T + E +IE++ +L E+LN K + S + K + Sbjct: 974 QQQITSLNADL-EKAQLFKT-ENEKKIEQISQLKEQLNDKDAQIASYE----QYKKYFDV 1027 Query: 1515 EVAKTNEMQTALENQEIEIVTLNDEITNLQNMV 1547 VAK T+ ++Q ++ T L N + Sbjct: 1028 LVAKPLPSLTSFQSQIYRLLPDAMSATELYNYI 1060 Score = 120 bits (288), Expect = 4e-25 Identities = 205/977 (20%), Positives = 426/977 (43%), Gaps = 102/977 (10%) Query: 151 IKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXX 210 + + +N + L+ K++ +TTI +L+E N + + N+ Sbjct: 113 LSKYENQIKALEDKIQTQKTTISELEEAANNSNDYLAEINRLKEEKSLLQSESSQT---- 168 Query: 211 XEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLE 270 + Q + +++ + ++ E K +L ++ S+D +I EE LL E + + Sbjct: 169 --EVNQLKSIIEKQTVELK-EIPILKNQLTMEVSSRDQKIKKYEEEIDLLNEKLGE-NED 224 Query: 271 HSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIEL 330 S + ++L Q KQ + ++ E+K A +T+L KI Sbjct: 225 VSSIKEDLIQKEDEISKYKLEILQFEKQV---AALKENSSEDKSEDLTAQITDLESKIAF 281 Query: 331 LEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLS 390 LEH N +R+ N + + G +S + +KK + LI ++S + +L Sbjct: 282 LEHENNSLREGNVTSDKQ----GLDS-LIEDITKKSNELID----------LRSKYQRL- 325 Query: 391 SETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIA 450 QDT+ KIN+ +I +LE LN+ + KE +SE K+TL+ Sbjct: 326 -----QDTN-KINEFKIIELENENAKLNESIDLKESDVSE-TVDLELISENKELKNTLLE 378 Query: 451 QLQL----EHQQHMEGPSLIHVGTNTEDVNE-IAKVQEQ---LKQELND-EIKDVNVKDL 501 + QL E++ ++ +++ T +D++E +A+ +E L +L D ++K ++ D Sbjct: 379 KEQLLSQSENEVNLLKNTILKNQTEVDDLSEKLAQSREDVTTLNNKLQDSQLKVGDLNDD 438 Query: 502 IEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFS----KVSDSNKEI 557 + KLKS E+ I + + ++K N+ L++ Q +D S +V++ + I Sbjct: 439 VLKLKSLEKTIELKDMDYSKLEDKYQQLKDNYD-NLEKSQVDVDELSSLKEQVNEKDLNI 497 Query: 558 VRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAI- 616 LT + K+AELE+ + + S + D KK E+ N +K+I Sbjct: 498 RSLTSQNEASESKIAELEKTLTTRDNEISELKS-ELDSFDFSKKESEINNATNQEIKSIK 556 Query: 617 -------SLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQID 669 + + K D Q ++ +E+ + L + +++++ +E K +LE+ +D Sbjct: 557 KELYTKDAEFDKLKLDYNQLRKNSSKQINELNEALDKFTN-ENEKILTEKK--YLEDSLD 613 Query: 670 ALSASKKELALVIENLKL---DKEQLYGTIK----DLENDKEDIMNKLQNYIQENMD--- 719 + ++ +L +L L DK+ Y +K +++ + E+ +N L+ +Q+ D Sbjct: 614 SKNSLLNKLEQENNSLNLIIKDKDSNYNVLKKKFQEIKRNNEEQINLLKQDVQDKNDKIA 673 Query: 720 -LTDKLEKMSAE--KISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKS 776 L KLE E ++++++ ++ SK + K+QE I+ + +LS+ S Sbjct: 674 ALPQKLELKDIEISQLNKIVKSHENDVLSKNNEIKTLRNKVQESREVIKQLNDKLSE-NS 732 Query: 777 RICRLEESIAVMEDRRYSL----ERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMD 832 + ++E I ED + L + ++ + + S+ + DEL + L + Sbjct: 733 VV--IDEKIRSKEDEIFKLKDNFKNSVNEKDEEISRLKSLLSQRNYKIDELTENVGSL-N 789 Query: 833 HDRVVEKQLLEIEHENKELQKKNQILLEENQNLQIS---LSDMQQHYNALVEKANRTDLA 889 HD +E + E ++ K +I+ ++ + + D+ Q N L K + Sbjct: 790 HD--LEVLSFKFEDNKEQFNKCEEIIQAKDDVISKKDELIEDINQQINRLENKIKLKNDD 847 Query: 890 ESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEK 949 E ++ L SNLK E L + K ++ E +T IE + + ++ Sbjct: 848 IEELNDDLSKKDTLISNLKEEISE-SNLKLNKLDDLSSQIKENDTLIEKLNDELALKEQE 906 Query: 950 YEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYIN 1009 ++N+ + ++ + E K IE N ++E+ K+ L +K+ Q + + + IN Sbjct: 907 VQENVRELDTDKSHITELKELIERKNKDIEDHKKL---LSEKNTQLLEFKD---LKPRIN 960 Query: 1010 EIN-KLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVS 1068 E+ + + ++ ++I +LN + AQ+ ++ E K+ Q + ++E++ Sbjct: 961 ELEVEKSDMMANYQQQITSLNADLEKAQL----FKTENEKKIEQ----ISQLKEQLNDKD 1012 Query: 1069 KQLLDSKQHNEELQILV 1085 Q+ +Q+ + +LV Sbjct: 1013 AQIASYEQYKKYFDVLV 1029 Score = 107 bits (256), Expect = 3e-21 Identities = 148/753 (19%), Positives = 348/753 (46%), Gaps = 65/753 (8%) Query: 843 EIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDL----AESESTKYQT 898 ++ ENK++ K N+++ + + +++Q N L +K ++ D E E + +T Sbjct: 29 QLNDENKDI-KSNKVVKNVLIQSESNNTNLQAKINELTDKVHKQDTYLKEKELELQEMET 87 Query: 899 QLRDLESNLKRITHEHQ-----TLIVQK-KKEIEDLEIEFNTQIESAIRDKKVLNEKYEK 952 +L++ + +K + ++ +++ K + +I+ LE + TQ ++ I + L E Sbjct: 88 RLKEKDLQIKEVESQNSGSSLNEMVLSKYENQIKALEDKIQTQ-KTTISE---LEEAANN 143 Query: 953 NIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEIN 1012 + +Y+ ++ +L+E K+ +++ + E +N++ +I+K + + + P Q E++ Sbjct: 144 SNDYLAEIN-RLKEEKSLLQSESSQTE-VNQLK-SIIEKQTVELK-EIPILKNQLTMEVS 199 Query: 1013 KLNALLKQKDEEIIALNQKIN-NAQVSYMSM-VSDYESKLAQFTTKLENMEEEMQRVSKQ 1070 + +K+ +EEI LN+K+ N VS + + E +++++ KLE ++ E Q + + Sbjct: 200 SRDQKIKKYEEEIDLLNEKLGENEDVSSIKEDLIQKEDEISKY--KLEILQFEKQVAALK 257 Query: 1071 LLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDX 1130 S+ +E+L + + + +I L+ + ++ + S IE ++ +N + Sbjct: 258 ENSSEDKSEDLTAQITDLESKIAFLEHENNSLREGNVTSDKQGLDSLIEDITKKSNELID 317 Query: 1131 XXXXXXXXXXXLKVQEEE--EFIQERSVLQEQSAKLNTELQECYT-KIIQ--LETLNTEL 1185 K+ E + E E + L E +++ E ++I E NT L Sbjct: 318 LRSKYQRLQDTNKINEFKIIELENENAKLNESIDLKESDVSETVDLELISENKELKNTLL 377 Query: 1186 TGHDVVNQEQ--INQLKSKLEQLNTENDNLLSTVAELR---SSISSAVDQRGFEIAELWK 1240 +++Q + +N LK+ + + TE D+L +A+ R +++++ + ++ +L Sbjct: 378 EKEQLLSQSENEVNLLKNTILKNQTEVDDLSEKLAQSREDVTTLNNKLQDSQLKVGDLND 437 Query: 1241 QHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQ 1300 L + +KT + S E KY+QL D+ + + + V +++++SL+ ++ Sbjct: 438 DVLKLKS--LEKTIELKDMDYSKLEDKYQQLKDNYDNLEKSQ----VDVDELSSLKEQVN 491 Query: 1301 DKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYK 1360 +K+ ++R+L + +E + K+A +L++E S+ Sbjct: 492 EKDLNIRSLTSQ------------NEASESKIA---ELEKTLTTRDNEISELKSELDSFD 536 Query: 1361 QMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTH-QLELKDSEIYQK 1419 +++S +N N N ++K DAE L+L + QL S+ + Sbjct: 537 FSKKESEIN-NATNQEIKSIKKELYT---------KDAEFDKLKLDYNQLRKNSSKQINE 586 Query: 1420 THEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKE 1479 +E T N++ ++ L + L + E E L L + + ++Y ++K+ Sbjct: 587 LNEALDKFTNENEKILTEKKYLEDSLDSKNSLLNKLEQENNSLNLIIKDKDSNYNVLKKK 646 Query: 1480 SEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDE 1539 + + E++N+ + N ++A L + LE + + +++ +++ E ++++ N+E Sbjct: 647 FQEIKRNNEEQINLLKQDVQDKNDKIAALPQKLELKDIEISQLNKIVKSHENDVLSKNNE 706 Query: 1540 ITNLQNMVRASSSKIQKHVSFASDTKQGRDEQL 1572 I L+N V+ S I++ S+ DE++ Sbjct: 707 IKTLRNKVQESREVIKQLNDKLSENSVVIDEKI 739 Score = 96.3 bits (229), Expect = 6e-18 Identities = 145/692 (20%), Positives = 315/692 (45%), Gaps = 68/692 (9%) Query: 147 LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINE-KDQIIEAKNKATTXXXXXXXXXXX 205 L NT+ EK+ LS + ++ +++ TIL Q ++++ +++ +++ TT Sbjct: 372 LKNTLLEKEQLLSQSENEVNLLKNTILKNQTEVDDLSEKLAQSREDVTT----------- 420 Query: 206 XXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARF 265 +D++ ++ + ++ + +++ L K IE KD+ S LE+ + L+ + Sbjct: 421 -LNNKLQDSQLKVGDLNDDVLKLKS--------LEKTIELKDMDYSKLEDKYQQLK-DNY 470 Query: 266 EISLEHSKL-AQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTEL 324 + +LE S++ EL L Q+ E S + E+E+ + ++EL Sbjct: 471 D-NLEKSQVDVDELSSLKEQVNEKDLNIRSLTSQN-EASESKIAELEKTLTTRDNEISEL 528 Query: 325 TKKIELLEHLNCQI---RQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASK 381 +++ + + TN+E+++ + T+ + L RK+ ++ Sbjct: 529 KSELDSFDFSKKESEINNATNQEIKSIKKELYTKDAEFDKLKLDYNQL--RKNSSKQINE 586 Query: 382 MKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDT----XXXX 437 + + ++E T+KK ++ + ++ L ++ +I +KD+ Sbjct: 587 LNEALDKFTNENEKILTEKKYLEDSLDSKNSLLNKLEQENNSLNLIIKDKDSNYNVLKKK 646 Query: 438 XXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEI-KDV 496 + I L+ + Q + + + +D+ EI+++ + +K ND + K+ Sbjct: 647 FQEIKRNNEEQINLLKQDVQDKNDKIAALPQKLELKDI-EISQLNKIVKSHENDVLSKNN 705 Query: 497 NVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNF-SKVSDSNK 555 +K L K++ + E I QLND++ ++N + + + K ++ K DNF + V++ ++ Sbjct: 706 EIKTLRNKVQESREVIKQLNDKL---SENSVVIDEKIRSKEDEIFKLKDNFKNSVNEKDE 762 Query: 556 EIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKA 615 EI RL L + K+ EL E G+L H ++ S + D ++ + E + + + Sbjct: 763 EISRLKSLLSQRNYKIDELTENVGSLN-HDLEVLSFKF--EDNKEQFNKCEEIIQAKDDV 819 Query: 616 ISLLESQKFDLVQELHILQQKY----DEVEDKLADISQLQS--DQVCSEIKSVHLE-EQI 668 IS + D+ Q+++ L+ K D++E+ D+S+ + + EI +L+ ++ Sbjct: 820 ISKKDELIEDINQQINRLENKIKLKNDDIEELNDDLSKKDTLISNLKEEISESNLKLNKL 879 Query: 669 DALSASKKELALVIENLK----LDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKL 724 D LS+ KE +IE L L ++++ +++L+ DK I + ++N D+ D Sbjct: 880 DDLSSQIKENDTLIEKLNDELALKEQEVQENVRELDTDKSHITELKELIERKNKDIEDH- 938 Query: 725 EKMSAEKISELL------AKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRI 778 +K+ +EK ++LL +IN E K A Q++ I ++ ++L K + Sbjct: 939 KKLLSEKNTQLLEFKDLKPRINELEVEKSDMM----ANYQQQ---ITSLNADLEKAQLFK 991 Query: 779 CRLEESIAVMEDRRYSLERKADQLGSYLQEKQ 810 E+ I + + L K Q+ SY Q K+ Sbjct: 992 TENEKKIEQISQLKEQLNDKDAQIASYEQYKK 1023 >UniRef50_A0DKF0 Cluster: Chromosome undetermined scaffold_54, whole genome shotgun sequence; n=3; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_54, whole genome shotgun sequence - Paramecium tetraurelia Length = 1892 Score = 140 bits (339), Expect = 3e-31 Identities = 207/1086 (19%), Positives = 462/1086 (42%), Gaps = 90/1086 (8%) Query: 476 NEIAKVQEQLKQELNDEI--KDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNH 533 NE +++ + ++LN ++ K+ ++ ++E+ + ++ LN++I AN+ +VK + Sbjct: 617 NEQLELKSRAVEQLNQQLFQKEQEIQQIVEQNQIHIQEAQHLNEQIGEANQ---EVKQLN 673 Query: 534 KLKLKQMQKTIDNFSKVSDSNKEIVRLTE-ELHHLSQKVAELEEEKGNLQLHLVDYDSGR 592 + L Q Q ++ DS + V L++ E L ++ L+ EK NLQ+ Sbjct: 674 QQLLSQ-QNELEQAKLQQDSLQNTVHLSKLENDQLKLQIETLKTEKQNLQVQ------SN 726 Query: 593 MIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQS 652 + D+ + + + ET L + ++ +L+ ++H ++ +E++++ +++ + Sbjct: 727 QNQDDLSNSLQQQKQQNETLLSQLQNSIQEQNNLINQIHSQLKENNELKEQNLLLNREKQ 786 Query: 653 DQVCSEIKSVH-LEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQ 711 D K + L Q+ L +++ LV +N +L IK+ + + +I N+ + Sbjct: 787 DIQLQNNKQIDDLLNQVKQLIQKQEQQELVYQN------ELQTIIKNSKVENTNIQNEYE 840 Query: 712 NYIQENMDLTD-KLEKMSAEKISELLAKINHEEQSKIQTQFG--------IDAKIQERDL 762 + IQ + ++E++ E +L +N +E S IQTQ ++ ++QE+ L Sbjct: 841 SQIQTIVKKHQMQIEELKDENKRQLDQFVNQQE-SVIQTQINQLQNQIQQLNKELQEKQL 899 Query: 763 YIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDE 822 + N E K +LE+ I E+ + ++++ +L +E +A E +E+E Sbjct: 900 QLVNKNKEFELLKENQTKLEQQI---EENKAVMKQQEQELLIKKEELNQAVQEIITKEEE 956 Query: 823 LVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQIL------LEENQN-LQISLSDMQQH 875 +LA + + + E LE++ +K + +K ++ +E+ ++ LQI D Sbjct: 957 FQEQLAQVNEKQKEFEDNCLELK--SKAIPEKESVIEQLRADIEQKESELQIQNEDFINQ 1014 Query: 876 YNALVEKANRTDLAESESTKYQTQLRDLESNLK---RITHEHQTLIVQKKKEIEDLEIEF 932 N L E + D+ E K L D + LK ++ + + K I+ L + Sbjct: 1015 QNLLFEMIKQKDV---EIKKLTEDLDDHSNRLKEASKVIDRYSNCNSELKGTIDSLNHQL 1071 Query: 933 NTQIESAIRDKKVL-NEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDK 991 Q + + D K+ N + E + L LQ +N + NL M +EE NK Sbjct: 1072 EKQ-QQILNDIKIKENTSTQIYDEKMKSLNEILQSKQNEVANLQMRLEEENK-------- 1122 Query: 992 HVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLA 1051 V KQQ Q Q ++ +K ++E I ++I + S + + S ++ L Sbjct: 1123 -VYKQQNQ------QSSQQMKTTEKRMKDLEKEKINYQEEIQKKETSIIQLESKLQASLK 1175 Query: 1052 QFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKEL-KETKLTFEMNIPKTE 1110 + + +++ + +QLL S Q EE +I V ++ +L KE L+ +++ Sbjct: 1176 EKEIMSNQFKNQIKELQQQLLSSNQGVEEQKIWVIHYKKEVDKLNKEVSLSQQISQQYQS 1235 Query: 1111 GMIISSTIEPMSDDANNV-DXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQ 1169 + I+ + N + D ++ ++E+ S+ Q+++ L E Sbjct: 1236 QKNDNDQIKQENQKLNKLLDNQQQQIVSLKKEVEQHKQEKSKLVESISQQENRILELEEI 1295 Query: 1170 ECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVD 1229 + +I+Q + + + +V Q++ Q +++L+ + + + + E + Sbjct: 1296 KLQKQILQGKVSELQKSQQEV--QQKYQQAQAQLQSVQDDLQHSKKEIQETKQKNKVLAQ 1353 Query: 1230 QRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTM 1289 Q+ E+++ ++ +A +E + E ++Q+ +S+ EQ ++Q E K+ Sbjct: 1354 QQQNEMSKFNQEIIAIQE----ELEQSRKIQMEIKKSEQEQREQNMQIRQNYEKLKLENQ 1409 Query: 1290 E---QVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXX 1346 + Q+ +Q ++ ++E + E + +Q++ ++E + Sbjct: 1410 QLNNQLDEIQQDMKYEKEEVLKKDETIYKLSDQVKYKTQQLEAQNTLINQVEQNKLSQTN 1469 Query: 1347 XXXXDL-RTENQSYKQMQEQSILNINEENAQ-LKKSSXXXXXXXXXXXXRVNDAEAKVLE 1404 + N S + + L IN+ ++ K+ +V D + + + Sbjct: 1470 QILQQSNQLTNLSKELFSLKQQLQINDAQSESYKREVERLRRELEFQEKQVEDYKQQTKK 1529 Query: 1405 LTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRL 1464 L+ QL+ ++K H + + ++ + L K ++ T S+ Sbjct: 1530 LSQQLD------FEKKHSQKQKIYEASELLSKIDNTLSPI-KGVKGQTLYGSSDS----- 1577 Query: 1465 KMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQT 1524 K + +T Q+E + LN L K+ +L ++LE+++ +++ Sbjct: 1578 KTQKRIFQQKTPQREYGFQNSNSASMLNASFNSQDQLAKENRKLKQSLEQKMKIIEQLEQ 1637 Query: 1525 ALENQE 1530 AL E Sbjct: 1638 ALLQSE 1643 Score = 140 bits (338), Expect = 4e-31 Identities = 244/1271 (19%), Positives = 542/1271 (42%), Gaps = 108/1271 (8%) Query: 379 ASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVI--SEKDTXXX 436 A + +Q+ E L + +IN++ + L VI SL +D YV K T Sbjct: 241 AGSERQKHTQVQGERLREGC--QINRS-LHILGNVINSLVEDKEQNRYVHYRDSKLTFLL 297 Query: 437 XXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDV 496 + LIA +Q + + E S + + V A+V E L + +K+ Sbjct: 298 KDSLGGNSRTHLIANIQQSNLFYQETFSTLQFSKRVKQVKNKARVNEDESGSL-ESLKN- 355 Query: 497 NVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKE 556 +K L ++L + + ++ +K I + H + + + + K+ + K Sbjct: 356 EIKRLKQELAKWIVGLQTTSKLAESPSKQNIIM---HNINFEDLNAKDQRYIKLEEILK- 411 Query: 557 IVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAI 616 V L + + E+E+ ++ + +E + K +I ++N RLK Sbjct: 412 -VYLEQSTESETALYVEIEKYLSGIKELREAFQLSSQLEQQL-KLIIRLQNEQIVRLKHA 469 Query: 617 SLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKS-VHLEEQIDALSASK 675 + E D +EL V K +D +++ + K+ + + E + L+ Sbjct: 470 NGAEDLSNDYQEELSKALLSQAAVMKKFSDSLRIKEGSAKNVEKAKLQINENVSMLNTIV 529 Query: 676 KELALVI-ENLKLDKE------QLYGTIKD---LENDKEDIMNKLQNYIQENMDLTDKLE 725 + + E KL K+ Q+Y +++ L+++KE I KL ++++ + L+ Sbjct: 530 TTVNESLDERKKLQKQIQQQFSQVYVPVEEFTQLQSEKEKINEKLTKFVEKEDKIKQSLD 589 Query: 726 KMSAEKISELLAKI-NHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEES 784 ++ E KI +H+++ Q +++ R +E + +L + + I ++ E Sbjct: 590 QIGITIHDEDEIKIIDHKQRDLTLDQQNEQLELKSRA--VEQLNQQLFQKEQEIQQIVEQ 647 Query: 785 --IAVMEDRRYSLE-----RKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVV 837 I + E + + + ++ QL L +Q + +Q+D L N + H + Sbjct: 648 NQIHIQEAQHLNEQIGEANQEVKQLNQQLLSQQNELEQAKLQQDSLQNTV-----HLSKL 702 Query: 838 EKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESEST--K 895 E L+++ E + +K+N + ++ NQN + +QQ ++ N T L++ +++ + Sbjct: 703 ENDQLKLQIETLKTEKQN-LQVQSNQNQDDLSNSLQQQ-----KQQNETLLSQLQNSIQE 756 Query: 896 YQTQLRDLESNLKRITH-EHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKN- 953 + + S LK + Q L++ ++K+ D++++ N QI+ + K L +K E+ Sbjct: 757 QNNLINQIHSQLKENNELKEQNLLLNREKQ--DIQLQNNKQIDDLLNQVKQLIQKQEQQE 814 Query: 954 IEYVTQLEAQLQ-----------EYKNNIENL----NMNVEELNKMNLELIDKHVQKQQT 998 + Y +L+ ++ EY++ I+ + M +EEL N +D+ V +Q++ Sbjct: 815 LVYQNELQTIIKNSKVENTNIQNEYESQIQTIVKKHQMQIEELKDENKRQLDQFVNQQES 874 Query: 999 QSPDYTEQYINEINKLNALLKQKDEEIIALNQK---INNAQVSYMSMVSDYESKLAQFTT 1055 Q N+I +LN L++K +++ N++ + Q + + ++ + Q Sbjct: 875 VIQTQINQLQNQIQQLNKELQEKQLQLVNKNKEFELLKENQTKLEQQIEENKAVMKQQEQ 934 Query: 1056 KLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMN-IPKTEGMI- 1113 +L +EE+ + ++++ + EE Q + + +++ KE ++ L + IP+ E +I Sbjct: 935 ELLIKKEELNQAVQEIITKE---EEFQEQLAQVNEKQKEFEDNCLELKSKAIPEKESVIE 991 Query: 1114 -ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECY 1172 + + IE + + + Q++ E + L + S L+E Sbjct: 992 QLRADIEQKESELQIQNEDFINQQNLLFEMIKQKDVEIKKLTEDLDDHS----NRLKEAS 1047 Query: 1173 TKIIQLETLNTELTG------HDVVNQEQI-NQLKSK---LEQLNTENDNLLSTVAELRS 1222 I + N+EL G H + Q+QI N +K K Q+ E L+ + + + Sbjct: 1048 KVIDRYSNCNSELKGTIDSLNHQLEKQQQILNDIKIKENTSTQIYDEKMKSLNEILQSKQ 1107 Query: 1223 SISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEE 1282 + + + R E +++KQ Q + TE ++ L + Y++ + ++S + Sbjct: 1108 NEVANLQMRLEEENKVYKQQNQQSSQQMKTTEKRMK-DLEKEKINYQEEIQKKETSIIQL 1166 Query: 1283 TNKI---VTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEIL--RSEIE--DEKVAFX 1335 +K+ + +++ S Q K Q KE + L +I ++ + E++ +++V+ Sbjct: 1167 ESKLQASLKEKEIMSNQFKNQIKELQQQLLSSNQGVEEQKIWVIHYKKEVDKLNKEVSLS 1226 Query: 1336 XXXXXXXXXXXXXXXDLRTENQSYKQM---QEQSILNINEENAQLKKSSXXXXXXXXXXX 1392 ++ ENQ ++ Q+Q I+++ +E Q K+ Sbjct: 1227 QQISQQYQSQKNDNDQIKQENQKLNKLLDNQQQQIVSLKKEVEQHKQEKSKLVESISQQE 1286 Query: 1393 XRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLT 1452 R+ + E L+ L+ K SE+ + E Q + ++V+ L +K I++ T Sbjct: 1287 NRILELEEIKLQ-KQILQGKVSELQKSQQEVQQKYQQAQAQLQSVQDDLQHSKKEIQE-T 1344 Query: 1453 YEKESELAILRLKMHENANHYETMQKESEIERVKLIE-ELNVKITESVSLNKQVAELNKA 1511 +K LA + N E + + E+E+ + I+ E+ E N Q+ + + Sbjct: 1345 KQKNKVLAQQQQNEMSKFNQ-EIIAIQEELEQSRKIQMEIKKSEQEQREQNMQIRQNYEK 1403 Query: 1512 LEEEVAKTN----EMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQG 1567 L+ E + N E+Q ++ ++ E++ ++ I L + V+ + +++ + + +Q Sbjct: 1404 LKLENQQLNNQLDEIQQDMKYEKEEVLKKDETIYKLSDQVKYKTQQLEAQNTLINQVEQN 1463 Query: 1568 RDEQLDNTMNK 1578 + Q + + + Sbjct: 1464 KLSQTNQILQQ 1474 Score = 110 bits (264), Expect = 4e-22 Identities = 174/845 (20%), Positives = 381/845 (45%), Gaps = 83/845 (9%) Query: 306 EKTEIEEKGSLE-IANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSK 364 E+ + E K L+ N E + ++ L QI+Q NKEL+ K + ++K + Sbjct: 855 EELKDENKRQLDQFVNQQESVIQTQI-NQLQNQIQQLNKELQEKQLQLVNKNKEFELLKE 913 Query: 365 KGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMV-IQSLNKDLVD 423 + L + K + + E LNQ + I K E + ++ + K+ D Sbjct: 914 NQTKLEQQIEENKAVMKQQEQELLIKKEELNQAVQEIITKEEEFQEQLAQVNEKQKEFED 973 Query: 424 -----KEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEI 478 K I EK++ K++ +LQ++++ + +L+ +DV EI Sbjct: 974 NCLELKSKAIPEKESVIEQLRADIEQKES---ELQIQNEDFINQQNLLFEMIKQKDV-EI 1029 Query: 479 AKVQEQLKQELNDEIKDVNVKDLIEKLKSA-EEQITQLNDEIDAANK--NMIKVKSNHKL 535 K+ E L N + V D S + I LN +++ + N IK+K N Sbjct: 1030 KKLTEDLDDHSNRLKEASKVIDRYSNCNSELKGTIDSLNHQLEKQQQILNDIKIKENTST 1089 Query: 536 KL-KQMQKTIDNF--SKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGR 592 ++ + K+++ SK ++ +RL EE Q+ + ++ + + D + + Sbjct: 1090 QIYDEKMKSLNEILQSKQNEVANLQMRLEEENKVYKQQNQQSSQQMKTTEKRMKDLEKEK 1149 Query: 593 M-IESDVYKK---MIEMENLAETRLKAISLLESQKFDLVQELH--ILQQKYDEVEDKLAD 646 + + ++ KK +I++E+ + LK ++ +Q + ++EL +L E K+ Sbjct: 1150 INYQEEIQKKETSIIQLESKLQASLKEKEIMSNQFKNQIKELQQQLLSSNQGVEEQKIWV 1209 Query: 647 ISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDI 706 I + +V K V L +QI S+K + +K + ++L K L+N ++ I Sbjct: 1210 IHYKK--EVDKLNKEVSLSQQISQQYQSQKNDN---DQIKQENQKLN---KLLDNQQQQI 1261 Query: 707 MNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIEN 766 ++ L+ ++++ KL E IS+ +I E+ K+Q Q + K+ E + Sbjct: 1262 VS-LKKEVEQHKQEKSKL----VESISQQENRILELEEIKLQKQI-LQGKVSELQKSQQE 1315 Query: 767 IESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQ-EDELVN 825 ++ + + ++++ +++ + + ++K L Q + +++ I ++EL Sbjct: 1316 VQQKYQQAQAQLQSVQDDLQHSKKEIQETKQKNKVLAQQQQNEMSKFNQEIIAIQEELEQ 1375 Query: 826 RLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQ---HYNALVEK 882 + M+ ++K E +N ++++ + L ENQ L L ++QQ + V K Sbjct: 1376 SRKIQME----IKKSEQEQREQNMQIRQNYEKLKLENQQLNNQLDEIQQDMKYEKEEVLK 1431 Query: 883 ANRTDLAESESTKYQTQLRDLESNLKRITHEHQ----TLIVQKKKEIEDLEIE-FNTQIE 937 + T S+ KY+TQ + ++ L +++ I+Q+ ++ +L E F+ + + Sbjct: 1432 KDETIYKLSDQVKYKTQQLEAQNTLINQVEQNKLSQTNQILQQSNQLTNLSKELFSLKQQ 1491 Query: 938 SAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQ 997 I D + +E Y++ +E +L +L+ + +E+ ++L++ L+ KH QKQ+ Sbjct: 1492 LQINDAQ--SESYKREVE---RLRRELEFQEKQVEDYKQQTKKLSQQ-LDFEKKHSQKQK 1545 Query: 998 T-QSPDYTEQYINEINKLNALLKQ--------KDEEIIALNQKI--------NNAQVSYM 1040 ++ + + N ++ + + Q K ++ I QK N+ S + Sbjct: 1546 IYEASELLSKIDNTLSPIKGVKGQTLYGSSDSKTQKRI-FQQKTPQREYGFQNSNSASML 1604 Query: 1041 SMVSDYESKLAQFTTKL-ENMEEEM---QRVSKQLLDSKQH----NEELQILVREQDDQI 1092 + + + +LA+ KL +++E++M +++ + LL S+Q +E+ ++Q+D+I Sbjct: 1605 NASFNSQDQLAKENRKLKQSLEQKMKIIEQLEQALLQSEQTLKEVHEKANQFCQQQEDEI 1664 Query: 1093 KELKE 1097 K++K+ Sbjct: 1665 KQIKD 1669 Score = 77.4 bits (182), Expect = 3e-12 Identities = 157/870 (18%), Positives = 357/870 (41%), Gaps = 72/870 (8%) Query: 159 SVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQM 218 SV+Q ++ ++ I L +++ EK + KNK E+ K M Sbjct: 874 SVIQTQINQLQNQIQQLNKELQEKQLQLVNKNK----EFELLKENQTKLEQQIEENKAVM 929 Query: 219 TKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQEL 278 + ++ + + E Q ++ E +++ + E K E E+ + + + Sbjct: 930 KQQEQELLIKKEELNQAVQEIITKEEEFQEQLAQVNEKQKEFEDNCLELKSKAIPEKESV 989 Query: 279 EQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQI 338 + + + E+ ++ +EI +TE +L +H N ++ Sbjct: 990 IEQLRADIEQKESELQIQNEDFINQQNLLFEMIKQKDVEIKKLTE-----DLDDHSN-RL 1043 Query: 339 RQTNKELEN----KLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETL 394 ++ +K ++ GT K+ L K NT++++ ++L Sbjct: 1044 KEASKVIDRYSNCNSELKGTIDSLNHQLEKQQQILNDIKIKENTSTQIYDE----KMKSL 1099 Query: 395 NQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQL 454 N+ K +NE+A L+M ++ N K Y + + KD ++ Sbjct: 1100 NEILQSK--QNEVANLQMRLEEEN-----KVYKQQNQQSSQQMKTTEKRMKDLEKEKINY 1152 Query: 455 EHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQ--- 511 + + + S+I + + + K +E + + ++IK++ + L+ + EEQ Sbjct: 1153 QEEIQKKETSIIQLESK---LQASLKEKEIMSNQFKNQIKELQ-QQLLSSNQGVEEQKIW 1208 Query: 512 ITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKV 571 + E+D NK +V + ++ + + DN ++ N+++ +L L + Q++ Sbjct: 1209 VIHYKKEVDKLNK---EVSLSQQISQQYQSQKNDN-DQIKQENQKLNKL---LDNQQQQI 1261 Query: 572 AELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELH 631 L++E ++ H + +++ES + ++ + L E +L+ +L+ + +L + Sbjct: 1262 VSLKKE---VEQH--KQEKSKLVES-ISQQENRILELEEIKLQK-QILQGKVSELQKSQQ 1314 Query: 632 ILQQKYDEVEDKLADI-SQLQ-SDQVCSEIK---SVHLEEQIDALSASKKELALVIENLK 686 +QQKY + + +L + LQ S + E K V ++Q + +S +E+ + E L+ Sbjct: 1315 EVQQKYQQAQAQLQSVQDDLQHSKKEIQETKQKNKVLAQQQQNEMSKFNQEIIAIQEELE 1374 Query: 687 LDKEQLYGTIKDLENDKEDIMNKLQNYIQ---ENMDLTDKLEKMSAEKISELLAKINHEE 743 ++ K + +E M QNY + EN L ++L+++ + E + +E Sbjct: 1375 QSRKIQMEIKKSEQEQREQNMQIRQNYEKLKLENQQLNNQLDEIQQDMKYEKEEVLKKDE 1434 Query: 744 Q-SKIQTQFGIDA-KIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKAD- 800 K+ Q +++ ++ I +E ++I + + + +SL+++ Sbjct: 1435 TIYKLSDQVKYKTQQLEAQNTLINQVEQNKLSQTNQILQQSNQLTNLSKELFSLKQQLQI 1494 Query: 801 ---QLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQL-LEIEHENKELQKKNQ 856 Q SY +E ++ E QE ++ + + + +QL E +H K+ + Sbjct: 1495 NDAQSESYKREVERLRRELEFQEKQVED----YKQQTKKLSQQLDFEKKHSQKQKIYEAS 1550 Query: 857 ILLEENQNLQISLSDM--QQHYNALVEKA-NRTDLAESESTKYQTQLRDLESNLKRITHE 913 LL + N + + Q Y + K R ++ +Y Q + S L + Sbjct: 1551 ELLSKIDNTLSPIKGVKGQTLYGSSDSKTQKRIFQQKTPQREYGFQNSNSASMLNASFNS 1610 Query: 914 HQTLIVQKKKEIEDLE--IEFNTQIESA-IRDKKVLNEKYEKNIEYVTQLEAQLQEYKNN 970 L + +K + LE ++ Q+E A ++ ++ L E +EK ++ Q E ++++ K+ Sbjct: 1611 QDQLAKENRKLKQSLEQKMKIIEQLEQALLQSEQTLKEVHEKANQFCQQQEDEIKQIKDQ 1670 Query: 971 IENLNMNVEELNKMNLELIDKHVQKQQTQS 1000 L + E ++ + KQ+ Q+ Sbjct: 1671 YSRLEQEHNTI-LAEREYENQQISKQKEQA 1699 Score = 71.3 bits (167), Expect = 2e-10 Identities = 176/955 (18%), Positives = 394/955 (41%), Gaps = 79/955 (8%) Query: 152 KEKDNALSVLQVKMKIMETTILDLQEKINE-KDQIIEAKNKATTXXXXXXXXXXXXXXXX 210 +E + A+ + K + + + + EK E +D +E K+KA Sbjct: 941 EELNQAVQEIITKEEEFQEQLAQVNEKQKEFEDNCLELKSKAIPEKESVIEQLRADIEQK 1000 Query: 211 XEDTKQQMTKM--QENFIAMEAEWKD-EKQRLLKDIESKDVRISSLEEANKLLEA---AR 264 + + Q Q+N + + KD E ++L +D++ R L+EA+K+++ Sbjct: 1001 ESELQIQNEDFINQQNLLFEMIKQKDVEIKKLTEDLDDHSNR---LKEASKVIDRYSNCN 1057 Query: 265 FEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMT-E 323 E+ L +LE+ + Q + + EI + E+AN+ Sbjct: 1058 SELKGTIDSLNHQLEKQQQILNDIKIKENT-STQIYDEKMKSLNEILQSKQNEVANLQMR 1116 Query: 324 LTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSP-SKKGSPLISRKSGRNTASKM 382 L ++ ++ + N Q Q K E ++ + E KK + +I +S + K Sbjct: 1117 LEEENKVYKQQNQQSSQQMKTTEKRMKDLEKEKINYQEEIQKKETSIIQLESKLQASLKE 1176 Query: 383 KSPWS--------QLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDL-----VDKEYVIS 429 K S +L + L+ + + K + + + LNK++ + ++Y Sbjct: 1177 KEIMSNQFKNQIKELQQQLLSSNQGVEEQKIWVIHYKKEVDKLNKEVSLSQQISQQYQSQ 1236 Query: 430 EKDTXXXXXXXXXXGK-----DTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQE- 483 + D K I L+ E +QH + S + V + ++ N I +++E Sbjct: 1237 KNDNDQIKQENQKLNKLLDNQQQQIVSLKKEVEQHKQEKSKL-VESISQQENRILELEEI 1295 Query: 484 -QLKQELNDEIKDV--NVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQM 540 KQ L ++ ++ + +++ +K + A+ Q+ + D++ + K + + K +K+ +Q Sbjct: 1296 KLQKQILQGKVSELQKSQQEVQQKYQQAQAQLQSVQDDLQHSKKEIQETKQKNKVLAQQQ 1355 Query: 541 QKTIDNFSKVSDSNKEIVRLTEELHH-----LSQKVAELEEEKGNLQLHLVDYDSGRMIE 595 Q + F N+EI+ + EEL + K +E E+ + N+Q+ +Y+ ++ Sbjct: 1356 QNEMSKF------NQEIIAIQEELEQSRKIQMEIKKSEQEQREQNMQIRQ-NYEKLKLEN 1408 Query: 596 SDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQV 655 + ++ E++ + + + + + L ++ + K ++E + I+Q++ +++ Sbjct: 1409 QQLNNQLDEIQQDMKYEKEEVLKKDETIYKLSDQV---KYKTQQLEAQNTLINQVEQNKL 1465 Query: 656 CSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQ 715 + + Q+ LS KEL + + L+++ Q +++E + ++ + + ++ Sbjct: 1466 SQTNQILQQSNQLTNLS---KELFSLKQQLQINDAQSESYKREVERLRRELEFQ-EKQVE 1521 Query: 716 ENMDLTDKL-EKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKY 774 + T KL +++ EK H ++ KI + +KI I+ ++ + + Y Sbjct: 1522 DYKQQTKKLSQQLDFEK--------KHSQKQKIYEASELLSKIDNTLSPIKGVKGQ-TLY 1572 Query: 775 KSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHD 834 S + ++ I + + + S L + + + +L L M Sbjct: 1573 GSSDSKTQKRIFQQKTPQREYGFQNSNSASMLNASFNSQDQLAKENRKLKQSLEQKMKII 1632 Query: 835 RVVEKQLLEIEHENKELQKK-NQILLEENQNL-QIS--LSDMQQHYNALV---EKANRTD 887 +E+ LL+ E KE+ +K NQ ++ + QI S ++Q +N ++ E N+ Sbjct: 1633 EQLEQALLQSEQTLKEVHEKANQFCQQQEDEIKQIKDQYSRLEQEHNTILAEREYENQQI 1692 Query: 888 LAESESTKYQTQ-LRDLESNLKRITHEHQTLIVQKKKE-IEDLEIEFNTQIESAIRDKKV 945 + E ++ Q L+D KR + Q + K E ++D+ + R Sbjct: 1693 SKQKEQALFKVQILQDEVLKSKRGSVGSQHIPGSKYSETVQDMSMRETPSSSHRFRLSDG 1752 Query: 946 LNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNK-MNLELIDKHVQKQQTQSPDYT 1004 + Y ++ ++L Q+ + LN + +L + + LE + + + Sbjct: 1753 QFKSYY-GVDAHSKLIYDTQKLLLENQRLNSQMCKLYQILGLEKNRSNKLEDGEKIIQSV 1811 Query: 1005 EQYINEIN--KLNALLKQKDEEIIALNQKINNAQVSYMSMVSD-YESKLAQFTTK 1056 + + E+ K+ LLK +EI L Q + + Y SM D ++KL + + Sbjct: 1812 QLLLQEVIVFKIQLLLKDCKQEIQNLIQAQPSRSLKYQSMEKDLQQTKLKYYAVE 1866 Score = 62.9 bits (146), Expect = 7e-08 Identities = 161/799 (20%), Positives = 335/799 (41%), Gaps = 76/799 (9%) Query: 49 ERQIKFERAQKCLENAALVSKRIKEHRKATAELLGRPFVPGISE-SLANT--LKQKEILM 105 E+Q +FE CLE L SK I E +++ E L SE + N + Q+ +L Sbjct: 966 EKQKEFE--DNCLE---LKSKAIPE-KESVIEQLRADIEQKESELQIQNEDFINQQNLLF 1019 Query: 106 EKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNALSVLQV-- 163 E IKQ K++ + T + + L TI ++ L Q Sbjct: 1020 EMIKQ-KDVEIKKLTEDLDDHSNRLKEASKVIDRYSNCNSELKGTIDSLNHQLEKQQQIL 1078 Query: 164 -KMKIMETTILDL-QEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKM 221 +KI E T + EK+ ++I+++K + + QQM Sbjct: 1079 NDIKIKENTSTQIYDEKMKSLNEILQSKQNEVANLQMRLEEENKVYKQQNQQSSQQMKTT 1138 Query: 222 QENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQX 281 ++ +E E K ++I+ K+ I LE + + +S + +EL+Q Sbjct: 1139 EKRMKDLEKE----KINYQEEIQKKETSIIQLESKLQASLKEKEIMSNQFKNQIKELQQQ 1194 Query: 282 XXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQT 341 + +Q I K E++ K + E++ +++++ + ++ N QI+Q Sbjct: 1195 LLSSNQG------VEEQKIWV-IHYKKEVD-KLNKEVSLSQQISQQYQSQKNDNDQIKQE 1246 Query: 342 NKELENKLATMGTESKAVSSPSKKGSPLISRKSGR-NTASKMKSPWSQLSSETLN-QDTD 399 N++L NKL + + + + S K+ KS + S+ ++ +L L Q Sbjct: 1247 NQKL-NKL--LDNQQQQIVSLKKEVEQHKQEKSKLVESISQQENRILELEEIKLQKQILQ 1303 Query: 400 KKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQH 459 K++ E+ K + +Q + + + + K+ ++AQ Q +++ Sbjct: 1304 GKVS--ELQKSQQEVQQKYQQAQAQLQSVQDDLQHSKKEIQETKQKNKVLAQQQ-QNEMS 1360 Query: 460 MEGPSLIHVGTNTEDVNEIAKVQEQLKQ-ELNDEIKDVNVKDLIEKLKSAEEQITQLNDE 518 +I + E++ + K+Q ++K+ E +++ ++ EKLK +Q+ DE Sbjct: 1361 KFNQEIIAI---QEELEQSRKIQMEIKKSEQEQREQNMQIRQNYEKLKLENQQLNNQLDE 1417 Query: 519 I---------DAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQ 569 I + K+ K + ++K K Q N + ++ + + T ++ S Sbjct: 1418 IQQDMKYEKEEVLKKDETIYKLSDQVKYKTQQLEAQN-TLINQVEQNKLSQTNQILQQSN 1476 Query: 570 KVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIE-MENLAETRLKAISLLESQKFDLVQ 628 ++ L +E +L+ L D+ +S+ YK+ +E + E + K + + Q L Q Sbjct: 1477 QLTNLSKELFSLKQQLQINDA----QSESYKREVERLRRELEFQEKQVEDYKQQTKKLSQ 1532 Query: 629 ELHILQQKYDEVEDKLADISQLQS--DQVCSEIKSVHLEEQIDALSASKKELALVIENLK 686 +L ++K+ + + K+ + S+L S D S IK V + Q S+ K + + Sbjct: 1533 QLDF-EKKHSQ-KQKIYEASELLSKIDNTLSPIKGV--KGQTLYGSSDSKTQKRIFQQKT 1588 Query: 687 LDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSK 746 +E YG +N M Q+ + ++ K S E+ +++ ++ EQ+ Sbjct: 1589 PQRE--YG----FQNSNSASMLNASFNSQDQLAKENRKLKQSLEQKMKIIEQL---EQAL 1639 Query: 747 IQTQFGIDAKIQERDLYIENIESELSKYKSRICRLE-ESIAVMEDRRYSLERKADQLGSY 805 +Q++ + ++ + + + E E+ + K + RLE E ++ +R Y ++ + Q Sbjct: 1640 LQSEQTLKEVHEKANQFCQQQEDEIKQIKDQYSRLEQEHNTILAEREYENQQISKQ---- 1695 Query: 806 LQEKQKAYSEYTIQEDELV 824 K++A + I +DE++ Sbjct: 1696 ---KEQALFKVQILQDEVL 1711 >UniRef50_Q9VJE5 Cluster: Restin homolog; n=4; Drosophila melanogaster|Rep: Restin homolog - Drosophila melanogaster (Fruit fly) Length = 1690 Score = 140 bits (339), Expect = 3e-31 Identities = 249/1188 (20%), Positives = 520/1188 (43%), Gaps = 128/1188 (10%) Query: 483 EQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKS---NHKLKLKQ 539 + L +E ++ + V+ +++ + A+ Q QL I+ +++++S N + K ++ Sbjct: 370 QDLLREKQQHVEKLMVERDLDR-EDAQNQALQLQKNINELKARIVELESALDNERKKTEE 428 Query: 540 MQKTIDNFSKVSDS-NKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDV 598 +Q +ID D N + E++H L K+ +L +LQ ++ D + SD Sbjct: 429 LQCSIDEAQFCGDELNAQSQVYKEKIHDLESKITKLVSATPSLQ-SILPPD----LPSDD 483 Query: 599 YKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSE 658 E+ L E +ES+ + ++E L++ + +++A LQS+ V + Sbjct: 484 GALQEEIAKLQEKMTIQQKEVESRIAEQLEEEQRLRENVKYLNEQIAT---LQSELVSKD 540 Query: 659 IKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENM 718 E ++ S S+ + + L+L KE+ K + + + KL E + Sbjct: 541 -------EALEKFSLSECGIENLRRELELLKEE---NEKQAQEAQAEFTRKLAEKSVEVL 590 Query: 719 DLTDKLEKMSAEKISELLAKINHEEQSKI-QTQFGI-DAKIQERDLYIENIESELSKYKS 776 L+ +L+ + A S ++N ++ +I QT+ + D +I+E + ++ + ++L+ K+ Sbjct: 591 RLSSELQNLKATSDSLESERVNKTDECEILQTEVRMRDEQIRELNQQLDEVTTQLNVQKA 650 Query: 777 RICRLEESIAVM----EDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMD 832 L++ + + E++ LE+ +L ++ K ++ Q ++ ++ L L + Sbjct: 651 DSSALDDMLRLQKEGTEEKSTLLEKTEKELVQSKEQAAKTLNDKE-QLEKQISDLKQLAE 709 Query: 833 HDRVV----EKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTD- 887 +++V E + +I+ E + ++++ + E ++ Q S+ + H + + + D Sbjct: 710 QEKLVREMTENAINQIQLEKESIEQQLALKQNELEDFQKKQSESEVHLQEIKAQNTQKDF 769 Query: 888 -LAESEST--KYQTQLRD-------LESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIE 937 L ES + K Q QL L++ L+ + E +T+I +K++E++ L+ + + + E Sbjct: 770 ELVESGESLKKLQQQLEQKTLGHEKLQAALEELKKEKETIIKEKEQELQQLQSK-SAESE 828 Query: 938 SAIRDKKVLNEKYEKNIEYVTQLEAQ-LQEYKNNIENLNMNVEELNKMNLELIDKHVQKQ 996 SA++ +V E+ ++ + ++ + + + I L EE + L+ +++ + Sbjct: 829 SALKVVQVQLEQLQQQAAASGEEGSKTVAKLHDEISQLKSQAEE-TQSELKSTQSNLEAK 887 Query: 997 QTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTK 1056 Q E K LL E+I L ++ Q + S +D ESK T + Sbjct: 888 SKQLEAANGSLEEEAKKSGHLL----EQITKLKSEVGETQAALSSCHTDVESK----TKQ 939 Query: 1057 LENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIK-ELK---------ETKLTFEMNI 1106 LE +++V+K+ +S+ +LQ V+E D + EL+ TKL+ + Sbjct: 940 LEAANAALEKVNKEYAESRAEASDLQDKVKEITDTLHAELQAERSSSSALHTKLSKFSDE 999 Query: 1107 PKTEGMIISSTIEPMSDDA-------NNVDXXXXXXXXXXXXLKVQ---EEEEFIQERSV 1156 T ++S + S + + LK + +E+ F + Sbjct: 1000 IATGHKELTSKADAWSQEMLQKEKELQELRQQLQDSQDSQTKLKAEGERKEKSFEESIKN 1059 Query: 1157 LQEQSAKLNTELQECYT------KIIQ--LETLNTELTGHDVVNQE---QINQLKSKLEQ 1205 LQE+ K TE E T K +Q LE N EL + + E +I LK+ +E Sbjct: 1060 LQEEVTKAKTENLELSTGTQTTIKDLQERLEITNAELQHKEKMASEDAQKIADLKTLVEA 1119 Query: 1206 LNTENDNLLSTVAELRSSISSAVDQRG-----FEI----AELWKQHLAQREADFQKTEHE 1256 + N N+ +T AEL + + ++ FE+ A++ + L ++ ++ E Sbjct: 1120 IQVANANISATNAELSTVLEVLQAEKSETNHIFELFEMEADMNSERLIEKVTGIKEELKE 1179 Query: 1257 LRVQLSAFESKYEQLLDSVQSSTQEETN----KIVTMEQVTSLQNKLQD-------KEEH 1305 +QL + K+E+L + ++ + Q E + E++T +Q LQ+ KEE Sbjct: 1180 THLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEEL 1239 Query: 1306 LRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQ 1365 ++NL+EK + + IE +++ + V L + KQ+QE+ Sbjct: 1240 VQNLEEKVRESSSIIEAQNTKLNESNVQL----ENKTSCLKETQDQLLESQKKEKQLQEE 1295 Query: 1366 SILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDS------EIYQK 1419 + ++ E Q+++++ V E K+ T QL+ + + E+ K Sbjct: 1296 A-AKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQATNKELQELLVK 1354 Query: 1420 THEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKE 1479 + E L + QQL + +++ +KE+ L L+ K+ E+ E+ QK+ Sbjct: 1355 SQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESNTVLES-QKK 1413 Query: 1480 SEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDE 1539 S E +E+ K +L ++ ++L + L + E+Q +L+ +++ + N+ Sbjct: 1414 SHNEIQDKLEQAQQK---ERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLLEKGNEF 1470 Query: 1540 ITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRA 1587 T L A K+ + A+ K EQL N + EL A+ +A Sbjct: 1471 DTQL-----AEYQKVIDEMDDAASVKSALLEQLQNRV-AELETALRQA 1512 Score = 126 bits (303), Expect = 7e-27 Identities = 233/1205 (19%), Positives = 497/1205 (41%), Gaps = 74/1205 (6%) Query: 146 HLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXX 205 H+ + E+D Q + ++ I +L+ +I E + ++ + K T Sbjct: 379 HVEKLMVERDLDREDAQNQALQLQKNINELKARIVELESALDNERKKTEELQCSIDEAQF 438 Query: 206 XXXXXXEDT---KQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEA 262 + K+++ ++ + + + L D+ S D + EE KL E Sbjct: 439 CGDELNAQSQVYKEKIHDLESKITKLVSATPSLQSILPPDLPSDDGALQ--EEIAKLQEK 496 Query: 263 ARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMT 322 + S++A++LE+ +A +++ K E EK SL + Sbjct: 497 MTIQQKEVESRIAEQLEEEQRLRENVKYLNEQIA--TLQSELVSKDEALEKFSLSECGIE 554 Query: 323 ELTKKIELLEHLN-CQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASK 381 L +++ELL+ N Q ++ E KLA E +SS L + K+ T+ Sbjct: 555 NLRRELELLKEENEKQAQEAQAEFTRKLAEKSVEVLRLSSE------LQNLKA---TSDS 605 Query: 382 MKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXX 441 ++S + E T+ ++ +I +L + + L ++ S D Sbjct: 606 LESERVNKTDECEILQTEVRMRDEQIRELNQQLDEVTTQLNVQKADSSALDDMLRLQKEG 665 Query: 442 XXGKDTLIAQLQLEHQQHME--GPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVK 499 K TL+ + + E Q E +L + ++++ ++ EQ ++L E+ + + Sbjct: 666 TEEKSTLLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQ--EKLVREMTENAIN 723 Query: 500 DLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVR 559 + + +S E+Q+ +E++ K + +S L+ + Q T +F V +S + + + Sbjct: 724 QIQLEKESIEQQLALKQNELEDFQKK--QSESEVHLQEIKAQNTQKDFELV-ESGESLKK 780 Query: 560 LTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLL 619 L ++L QK L EK L + + +I+ + +++ ++++ + A+ ++ Sbjct: 781 LQQQLE---QKT--LGHEKLQAALEELKKEKETIIK-EKEQELQQLQSKSAESESALKVV 834 Query: 620 ESQKFDLVQELHILQQKYDEVEDKLAD-ISQL--QSDQVCSEIKSVHLEEQIDALSASKK 676 + Q L Q+ ++ + KL D ISQL Q+++ SE+KS L A K Sbjct: 835 QVQLEQLQQQAAASGEEGSKTVAKLHDEISQLKSQAEETQSELKSTQSN-----LEAKSK 889 Query: 677 ELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELL 736 +L +L+ + ++ ++ + K ++ + D+ K +++ A + L Sbjct: 890 QLEAANGSLEEEAKKSGHLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAA--L 947 Query: 737 AKINHEEQSKIQTQFGIDAKIQE-RDLYIENIESELSKYKSRICRLEESIAVMEDRRYSL 795 K+N E + K++E D +++E S + +L + + L Sbjct: 948 EKVNKEYAESRAEASDLQDKVKEITDTLHAELQAERSSSSALHTKLSKFSDEIATGHKEL 1007 Query: 796 ERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLE-IEHENKELQKK 854 KAD + +K+K E Q + + L EK E I++ +E+ K Sbjct: 1008 TSKADAWSQEMLQKEKELQELRQQLQDSQDSQTKLKAEGERKEKSFEESIKNLQEEVTKA 1067 Query: 855 NQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEH 914 LE + Q ++ D+Q+ + + SE + L+ L ++ Sbjct: 1068 KTENLELSTGTQTTIKDLQERLEITNAELQHKEKMASEDAQKIADLKTLVEAIQVANANI 1127 Query: 915 QTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENL 974 + +E L+ E + + + E+ IE VT ++ +L+E ++ Sbjct: 1128 SATNAELSTVLEVLQAEKSETNHIFELFEMEADMNSERLIEKVTGIKEELKETHLQLDER 1187 Query: 975 NMNVEELNKM--NLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKI 1032 EEL + + ++ +Q++ S + + + +L +KQK+E + L +K+ Sbjct: 1188 QKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKV 1247 Query: 1033 NNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQI 1092 + S++ +KL + +LEN ++ QLL+S++ ++LQ + ++ Sbjct: 1248 RESS----SIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGEL 1303 Query: 1093 KELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXL-KVQEEEEFI 1151 ++++E + ++ K E ++ E + + +D L K QE E + Sbjct: 1304 QQVQEANGDIKDSLVKVE-ELVKVLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNL 1362 Query: 1152 QERSVL----QEQSAKLNTELQECY-TKIIQLETLNTELTGHDVVNQEQ---INQLKSKL 1203 Q S+ +Q + N EL+E K L+ L +L + V + Q N+++ KL Sbjct: 1363 QGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKL 1422 Query: 1204 EQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSA 1263 EQ + L ++L +S + Q E+ ++ L Q++ +K +E QL Sbjct: 1423 EQAQQKERTLQEETSKLAEQLSQ-LKQANEEL----QKSLQQKQLLLEK-GNEFDTQL-- 1474 Query: 1264 FESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEIL 1323 ++Y++++D + + + K +EQ LQN++ + E LR + + + L Sbjct: 1475 --AEYQKVIDEMDDAA---SVKSALLEQ---LQNRVAELETALRQANDAQKTAYLETKEL 1526 Query: 1324 RSEIE 1328 R ++E Sbjct: 1527 RRQLE 1531 Score = 112 bits (270), Expect = 7e-23 Identities = 207/1006 (20%), Positives = 407/1006 (40%), Gaps = 90/1006 (8%) Query: 51 QIKFERAQK-CLENAALVSKRIKEHRKATAELLGRPFVPGISESLANTLKQKEILMEKIK 109 Q+ ++A L++ + K E + E + V E A TL KE L ++I Sbjct: 644 QLNVQKADSSALDDMLRLQKEGTEEKSTLLEKTEKELVQS-KEQAAKTLNDKEQLEKQIS 702 Query: 110 QYKELSKRSSTT--IVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNALSVLQVKMKI 167 K+L+++ + QL + ++K + V ++K Sbjct: 703 DLKQLAEQEKLVREMTENAINQIQLEKESIEQQLALKQNELEDFQKKQSESEVHLQEIKA 762 Query: 168 METT----ILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQE 223 T +++ E + + Q +E K ++ +Q++ ++Q Sbjct: 763 QNTQKDFELVESGESLKKLQQQLEQKTLGHEKLQAALEELKKEKETIIKEKEQELQQLQS 822 Query: 224 NFIAMEAEWK-------DEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQ 276 E+ K +Q+ E ++ L + L++ E E Sbjct: 823 KSAESESALKVVQVQLEQLQQQAAASGEEGSKTVAKLHDEISQLKSQAEETQSELKSTQS 882 Query: 277 ELEQXXXXXXXXXXXXXXLAKQS---IEPSCEEKTEIEEKGSLEIANMTELTKKIELLEH 333 LE AK+S +E + K+E+ E + + T++ K + LE Sbjct: 883 NLEAKSKQLEAANGSLEEEAKKSGHLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEA 942 Query: 334 LNCQIRQTNKEL-ENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSE 392 N + + NKE E++ + K + L ++ R+++S + + S+ S E Sbjct: 943 ANAALEKVNKEYAESRAEASDLQDKVKEITDTLHAEL---QAERSSSSALHTKLSKFSDE 999 Query: 393 --TLNQDTDKKIN--KNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTL 448 T +++ K + E+ + E +Q L + L D + + + Sbjct: 1000 IATGHKELTSKADAWSQEMLQKEKELQELRQQLQDSQ---DSQTKLKAEGERKEKSFEES 1056 Query: 449 IAQLQLEHQQHMEGPSLIHVGTNT--EDVNEI-----AKVQEQLKQELNDEIKDVNVKDL 501 I LQ E + + GT T +D+ E A++Q + K D K ++K L Sbjct: 1057 IKNLQEEVTKAKTENLELSTGTQTTIKDLQERLEITNAELQHKEKMASEDAQKIADLKTL 1116 Query: 502 IEKLKSAEEQITQLNDEIDAANKNMIKVKS--NHKLKLKQMQKTIDN---FSKVSDSNKE 556 +E ++ A I+ N E+ + + KS NH +L +M+ +++ KV+ +E Sbjct: 1117 VEAIQVANANISATNAELSTVLEVLQAEKSETNHIFELFEMEADMNSERLIEKVTGIKEE 1176 Query: 557 IVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAI 616 + +L +K ELEE+ Q S + ++ + E L E + Sbjct: 1177 LKETHLQLDERQKKFEELEEKLKQAQ------QSEQKLQQE---SQTSKEKLTEIQQSLQ 1227 Query: 617 SLLES--QKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSAS 674 L +S QK +LVQ L ++ + + A ++L V E K+ L+E D L S Sbjct: 1228 ELQDSVKQKEELVQNLEEKVRESSSIIE--AQNTKLNESNVQLENKTSCLKETQDQLLES 1285 Query: 675 -KKELALVIENLKLDKE-----QLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMS 728 KKE L E KL E + G IKD E+++ L+ +Q D + + Sbjct: 1286 QKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQATN 1345 Query: 729 AEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVM 788 E + ELL K E + + K+Q+ +E EL K +C+ E + Sbjct: 1346 KE-LQELLVKSQENEGNLQGESLAVTEKLQQ----LEQANGEL---KEALCQKENGLK-- 1395 Query: 789 EDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHEN 848 L+ K D+ + L+ ++K+++E + ++ + L + + +QL +++ N Sbjct: 1396 -----ELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQAN 1450 Query: 849 KELQK---KNQILLEENQNLQISLSDMQQHYNALVEKAN-RTDLAESESTKYQTQLRDLE 904 +ELQK + Q+LLE+ L++ Q+ + + + A+ ++ L E + Q ++ +LE Sbjct: 1451 EELQKSLQQKQLLLEKGNEFDTQLAEYQKVIDEMDDAASVKSALLE----QLQNRVAELE 1506 Query: 905 SNLKRITHEHQTLIVQKK---KEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLE 961 + L++ +T ++ K +++E LE+E + ++ S + + K E V L+ Sbjct: 1507 TALRQANDAQKTAYLETKELRRQLESLELEKSREVLSLKAQMNGASSRSGKGDE-VESLD 1565 Query: 962 AQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQY 1007 + K N LN + ++ + N + + VQ +T D+T+ + Sbjct: 1566 IETSLAKINF--LNSIIADMQQKN-DALKAKVQTLETLPMDFTKPH 1608 Score = 90.6 bits (215), Expect = 3e-16 Identities = 150/813 (18%), Positives = 325/813 (39%), Gaps = 72/813 (8%) Query: 748 QTQFGIDAKIQERDLYIEN--IESELSKY--KSRICRLEESIAVMEDRRYSLERKADQLG 803 ++QF + ++E+ ++E +E +L + +++ +L+++I ++ R LE D Sbjct: 364 KSQFSMQDLLREKQQHVEKLMVERDLDREDAQNQALQLQKNINELKARIVELESALDNER 423 Query: 804 SYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQK-KNQILLEEN 862 +E Q + E DEL + V + +E ++ ++ LQ L ++ Sbjct: 424 KKTEELQCSIDEAQFCGDELNAQSQVYKEKIHDLESKITKLVSATPSLQSILPPDLPSDD 483 Query: 863 QNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKK 922 LQ ++ +Q+ + +K + +AE + + +LR+ L Q+ +V K Sbjct: 484 GALQEEIAKLQEKMT-IQQKEVESRIAEQ--LEEEQRLRENVKYLNEQIATLQSELVSKD 540 Query: 923 KEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELN 982 + +E + IE+ R+ ++L E+ EK + Q E + + ++E L ++ E Sbjct: 541 EALEKFSLS-ECGIENLRRELELLKEENEKQAQEA-QAEFTRKLAEKSVEVLRLSSE--- 595 Query: 983 KMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSM 1042 NL+ ++ ++ D E E+ + +DE+I LNQ+++ Sbjct: 596 LQNLKATSDSLESERVNKTDECEILQTEV-------RMRDEQIRELNQQLDEVTTQLNVQ 648 Query: 1043 VSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTF 1102 +D + + E EE+ + K + Q E+ + +++ K++ + K Sbjct: 649 KADSSALDDMLRLQKEGTEEKSTLLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLA 708 Query: 1103 EMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSA 1162 E + M+++A N LK E E+F Q++ + Sbjct: 709 EQE----------KLVREMTENAINQIQLEKESIEQQLALKQNELEDF-------QKKQS 751 Query: 1163 KLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRS 1222 + LQE ++ NT+ V + E + +L+ +LEQ ++ L + + EL+ Sbjct: 752 ESEVHLQE-------IKAQNTQKDFELVESGESLKKLQQQLEQKTLGHEKLQAALEELKK 804 Query: 1223 SISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEE 1282 + + ++ E+ Q L + A+ + ++VQL EQL +S +E Sbjct: 805 EKETIIKEKEQEL-----QQLQSKSAESESALKVVQVQL-------EQLQQQAAASGEEG 852 Query: 1283 TNKIVTM-EQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXX 1341 + + + ++++ L+++ ++ + L++ Q Q+E +E+E Sbjct: 853 SKTVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKK-SGHLLEQ 911 Query: 1342 XXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAK 1401 + + S E + NA L+K + +D + K Sbjct: 912 ITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALEKVNKEYAESRA----EASDLQDK 967 Query: 1402 VLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAI 1461 V E+T L + + L++ +DE ++L +KE EL Sbjct: 968 VKEITDTLHAELQAERSSSSALHTKLSKFSDEIATGHKELTSKADAWSQEMLQKEKELQE 1027 Query: 1462 LRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNE 1521 LR ++ ++ + ++ E E + K EE S+ E+ KA E + + Sbjct: 1028 LRQQLQDSQDSQTKLKAEGE-RKEKSFEE---------SIKNLQEEVTKAKTENLELSTG 1077 Query: 1522 MQTALENQEIEIVTLNDEITNLQNMVRASSSKI 1554 QT +++ + + N E+ + + M + KI Sbjct: 1078 TQTTIKDLQERLEITNAELQHKEKMASEDAQKI 1110 Score = 64.9 bits (151), Expect = 2e-08 Identities = 131/711 (18%), Positives = 287/711 (40%), Gaps = 44/711 (6%) Query: 878 ALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIE 937 +L + +T L+ + S + T + + S T + Q+K I + + Sbjct: 307 SLSPSSKKTRLSRTGSRESLTSIGTMNSIATTATSRMRMNAQQRKSSTPVKPILATPKSQ 366 Query: 938 SAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLEL---IDKHVQ 994 +++D +L EK + + + + + ++ +N L N+ EL +EL +D + Sbjct: 367 FSMQD--LLREKQQHVEKLMVERDLDREDAQNQALQLQKNINELKARIVELESALDNERK 424 Query: 995 K-QQTQ-SPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVS-DYESKLA 1051 K ++ Q S D + +E+N + + K+K ++ + K+ +A S S++ D S Sbjct: 425 KTEELQCSIDEAQFCGDELNAQSQVYKEKIHDLESKITKLVSATPSLQSILPPDLPSDDG 484 Query: 1052 QFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEG 1111 ++ ++E+M K++ E + +RE +K L E T + + + Sbjct: 485 ALQEEIAKLQEKMTIQQKEVESRIAEQLEEEQRLREN---VKYLNEQIATLQSELVSKDE 541 Query: 1112 MIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQEC 1171 + ++ + N+ + + EF ++ + + +L++ELQ Sbjct: 542 ALEKFSLSECGIE--NLRRELELLKEENEKQAQEAQAEFTRKLAEKSVEVLRLSSELQNL 599 Query: 1172 YTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQR 1231 LE+ T + Q ++ ++ +LN + D + +T ++ + SSA+D Sbjct: 600 KATSDSLESERVNKTDECEILQTEVRMRDEQIRELNQQLDEV-TTQLNVQKADSSALD-- 656 Query: 1232 GFEIAELWKQHLAQREADFQKTEHELRVQ--------LSAFESKYEQLLDSVQSSTQEET 1283 ++ L K+ ++ +KTE EL VQ L+ E +Q+ D Q + QE+ Sbjct: 657 --DMLRLQKEGTEEKSTLLEKTEKEL-VQSKEQAAKTLNDKEQLEKQISDLKQLAEQEKL 713 Query: 1284 NKIVTMEQVTSLQNKLQDKEEHL---RNLQEKYADVINQIEILRSEIEDEKVAFXXXXXX 1340 + +T + +Q + + E+ L +N E + ++ E+ EI+ + Sbjct: 714 VREMTENAINQIQLEKESIEQQLALKQNELEDFQKKQSESEVHLQEIKAQNTQKDFELVE 773 Query: 1341 XXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEA 1400 L + ++++Q ++ + +E + K +++ Sbjct: 774 SGESLKKLQQQLEQKTLGHEKLQA-ALEELKKEKETIIKEKEQELQQLQSKSAE-SESAL 831 Query: 1401 KVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYE---KES 1457 KV+++ QLE + E + T+ + +DE ++ Q E + ++ K Sbjct: 832 KVVQV--QLEQLQQQAAASGEEGSKTVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSK 889 Query: 1458 ELAILRLKMHENANH----YETMQK-ESEIERVKLIEELNVKITESVSLNKQVAELNKAL 1512 +L + E A E + K +SE+ + L+ T+ S KQ+ N AL Sbjct: 890 QLEAANGSLEEEAKKSGHLLEQITKLKSEVGETQAA--LSSCHTDVESKTKQLEAANAAL 947 Query: 1513 EEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASD 1563 E+ + E + + + ++ + D + R+SSS + +S SD Sbjct: 948 EKVNKEYAESRAEASDLQDKVKEITDTLHAELQAERSSSSALHTKLSKFSD 998 Score = 40.7 bits (91), Expect = 0.32 Identities = 59/334 (17%), Positives = 135/334 (40%), Gaps = 20/334 (5%) Query: 49 ERQIKFERAQKCLENAALVSKRIKEHRKATAELLGRPFVPGISESLANTLKQKEILM--- 105 ERQ KFE ++ L+ A +++++ + + E L + + L +++KQKE L+ Sbjct: 1186 ERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTE--IQQSLQELQDSVKQKEELVQNL 1243 Query: 106 -EKIKQYKELSKRSSTTIVRXXXXXXXXXX--XXXXXQLGDVTHLSNTIKEKDNALSVLQ 162 EK+++ + + +T + QL + ++E+ LS Sbjct: 1244 EEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGEL 1303 Query: 163 VKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQ 222 +++ I D K+ E +++E K +A T +++ +Q Sbjct: 1304 QQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQ 1363 Query: 223 ENFIAMEAEWKDEKQ---RLLKDIESKDVRI----SSLEEANKLLEAAR-----FEISLE 270 +A+ + + +Q L + + K+ + L+E+N +LE+ + + LE Sbjct: 1364 GESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLE 1423 Query: 271 HSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIEL 330 ++ + Q A + ++ S ++K + EKG+ + E K I+ Sbjct: 1424 QAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLLEKGNEFDTQLAEYQKVIDE 1483 Query: 331 LEHLNCQIRQTNKELENKLATMGTESKAVSSPSK 364 ++ ++L+N++A + T + + K Sbjct: 1484 MDDAASVKSALLEQLQNRVAELETALRQANDAQK 1517 >UniRef50_A0D7Y2 Cluster: Chromosome undetermined scaffold_40, whole genome shotgun sequence; n=1; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_40, whole genome shotgun sequence - Paramecium tetraurelia Length = 1498 Score = 140 bits (338), Expect = 4e-31 Identities = 238/1228 (19%), Positives = 541/1228 (44%), Gaps = 98/1228 (7%) Query: 387 SQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKD 446 SQ + NQ+ + + N+ +LE I+SL ++ K +S+ + + Sbjct: 2 SQTPEQNRNQEVWLRNSLNKNNRLEFEIKSLQNEVKTKNQQLSQLEMDYKGQVNQLQQQI 61 Query: 447 TLIAQLQLEHQQHMEG-PSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDL---- 501 + LQL+ QQ +G D N K Q + QE N+ KD + ++L Sbjct: 62 QINQSLQLQIQQISQGNTDQKKAIEQLTDQNNQLKNQLKQVQETNNIEKDQSKQNLERAN 121 Query: 502 --IEKLKSAEEQITQLNDEIDAANKNMI-KVKSNHKLKLKQMQKTIDNFSKVSDSNKEIV 558 I+KLK+ Q+ + ND + I ++ +N K ++++Q+ I ++S ++K I Sbjct: 122 TDIQKLKNEILQLQRNNDSLQQQKTYQISQLDTNSKKVIEELQEQIRKM-QLSATSK-IE 179 Query: 559 RLTEEL----HHLSQKVAELEEEKGNLQLHLVDYD------SGRMIESDVYKKMIEM--- 605 LT EL L + + E+ +K L +Y+ S ++I++ ++ + Sbjct: 180 SLTSELSLKNDQLDKLMKEINIKKNELYQSTANYEAVNATKSQQLIQAQQIQQKCQQDFN 239 Query: 606 ENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLE 665 + LA+ +L+A + + ++ Q+ I+++ ++ K +I +++Q +I + + + Sbjct: 240 DKLAQFQLQAQMKITQMEQEIGQKNTIIEKANQDLAKKAQEIK--ENNQNFEQINNQNQK 297 Query: 666 E-QIDALSASKKELALVIENLKLDKEQLYGTIK-DLENDKEDIMNKLQNYIQENMDLTDK 723 + Q + K +LA+ EN + D+++ G +K ++N ++D+ + Q+ Q L ++ Sbjct: 298 KLQQMMIQVQKLQLAIESENTQYDRKK--GDLKVQIDNLEKDLNMQQQSSNQYTQKLNNE 355 Query: 724 LEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEE 783 + ++ + + +L +++ + +S +Q DA+I++ +L + + + E+ ++ + E Sbjct: 356 INQLKNQNL-DLQRQLSEKHKSLCLSQTESDAQIKQLNLQVASFQKEIQLKNQQLQQAES 414 Query: 784 SIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLE 843 + M+ + ++ DQ+ +++K E IQ D+L N M +V+ L Sbjct: 415 QLLEMKVLKV---QEIDQMKLKFDQREK---ELLIQNDQLNNNNK--MQSQKVI---TLS 463 Query: 844 IEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDL 903 E N+++++ +Q E+ NL S + Y + + + LA+ + T + ++ + Sbjct: 464 NEELNRQIKQVDQFWTEKYNNL--SKQTKEDIYQ--LTQQYQMQLAQMDQTN-KEKIYVI 518 Query: 904 ESNLKRITHEHQTLI-VQ---KKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQ 959 E N + + + L VQ K+I DL+ E I K LNE +K + ++ Sbjct: 519 EQNHNQFLNSQKELFNVQLSLLNKQILDLQKERENSIIQLDLMKVKLNELQDKTQNFNSR 578 Query: 960 LEAQLQEYKNNIENLNMNVEE-LNKMNLELI--DKHVQKQQTQSPDYTEQYINEINKLNA 1016 + + + +N + L + EE LN +N + + K + QT+ +QY N + + Sbjct: 579 DQRKDELMQNQMATLKNSKEELLNVINQQNLAHKKEIYNLQTKIDQLQQQYDNSVREGKQ 638 Query: 1017 LLKQKDEEIIALNQKIN---NAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLD 1073 + +Q + Q N ++ +D +S++ + ++L +E ++V +L Sbjct: 639 IKEQLKLSQLEAQQVYNLSHQKNKESLNAQADKDSEIIKLQSELSRVETLYKQVVLELKI 698 Query: 1074 SKQHNEELQIL----VREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVD 1129 + +LQ++ ++E+D +I K L + + + + I + +E +AN Sbjct: 699 INEQKNDLQVIDDFQLKEKDIEIGNQKSYILELKQKLQQLQKRI--NELELQLQNANK-- 754 Query: 1130 XXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHD 1189 ++ + IQ+R + QE+ + + EL E + ++++T N L Sbjct: 755 KLGQKDQEAKKEIENLNQRITIQKRQI-QEERERCD-ELAE--AQEMEVQTWNERLKEQQ 810 Query: 1190 VVNQEQINQLKSKLEQLNTENDNLLSTVAELRSS---ISSAVDQRGFEIAELWKQHLAQR 1246 +N++ I QL +L+Q ++N L++ + L+ +++ Q + E KQ + Sbjct: 811 KLNEDLIIQL-MRLQQQTSQNSGLINELQNLKQQFEIVTNQYKQLQEDAEEATKQKSMVK 869 Query: 1247 EADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETN-KIVTME-QVTSLQNKLQDKEE 1304 Q ++ Q+ +QL D QS+ ++ I+ Q+ +L + L K Sbjct: 870 NVQIQMLQNHYNKQMDVLT---QQLEDMKQSNLNQKLEFPIMDFNVQIIALNDLLVKKNA 926 Query: 1305 HLRNLQ-EKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTEN-QSYKQM 1362 + L+ + ++ + ++ + E + R +N Q + Sbjct: 927 EINQLKSQTQQKLLEKDSVIDQQREYAQQLLSEFEKLQVQLMDQHEFQERADNLQMINEE 986 Query: 1363 QEQSILNINEENAQLKKSSXXXXXXXXXXXXR---VNDAEAKVLELTHQLELKDSEIYQK 1419 ++ SI+ + EE A+LK+ + + D + + +L +L+ K I K Sbjct: 987 KDNSIIYLKEEIAKLKQENKLIKGKLDLKEQSMVVIQDQQQLIKQLKIELQNKQKNIQPK 1046 Query: 1420 THEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANH----YET 1475 + T ++ + ++ + ++ + ES+ + EN N+ + Sbjct: 1047 QIAVSHQQTMKS-SIHRMSKRSESSRQEKSEVDWNGESQF------LMENGNNKLPCFHQ 1099 Query: 1476 MQKESEIERVKLIEELNVKITE-SVSLNKQVAELN---KALEEEVAKTNEMQTALENQEI 1531 ES + KLIE++N +I + ++ L QV LN ++L+ ++ +T + ++N+ Sbjct: 1100 QSSESFTDN-KLIEKMNSEIVDTNIRLRNQVDLLNQDKQSLQNDLTRTIQSLNQVKNENS 1158 Query: 1532 EIVTLNDEITNLQNMVRASSSKIQKHVS 1559 E++ + + + K+++ ++ Sbjct: 1159 ELILKLQYVQKALESSQQNQEKLEREIN 1186 Score = 131 bits (317), Expect = 1e-28 Identities = 251/1367 (18%), Positives = 582/1367 (42%), Gaps = 138/1367 (10%) Query: 172 ILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAE 231 I +LQE+I + +K ++ T K ++ + N+ A+ A Sbjct: 160 IEELQEQIRKMQLSATSKIESLTSELSLKNDQLDKLMKEINIKKNELYQSTANYEAVNAT 219 Query: 232 WKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXX 291 + Q+L I+++ ++ ++ N L + + ++ +++ QE+ Q Sbjct: 220 ---KSQQL---IQAQQIQQKCQQDFNDKLAQFQLQAQMKITQMEQEIGQKNTIIEKANQD 273 Query: 292 XXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIEL-LEHLNCQIRQTNKEL----E 346 A Q I+ + + +I + ++ M +K++L +E N Q + +L + Sbjct: 274 LAKKA-QEIKENNQNFEQINNQNQKKLQQMMIQVQKLQLAIESENTQYDRKKGDLKVQID 332 Query: 347 NKLATMGTESKAVSSPSKKGSPLISRKSGRNT--ASKMKSPWSQLSSETLNQDTDKKINK 404 N + + ++ + ++K + I++ +N ++ L D K Sbjct: 333 NLEKDLNMQQQSSNQYTQKLNNEINQLKNQNLDLQRQLSEKHKSLCLSQTESDAQIKQLN 392 Query: 405 NEIAKLEMVIQSLNKDLVDKEY------VISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQ 458 ++A + IQ N+ L E V+ ++ K+ LI QL + Sbjct: 393 LQVASFQKEIQLKNQQLQQAESQLLEMKVLKVQEIDQMKLKFDQREKELLIQNDQLNNNN 452 Query: 459 HMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDE 518 M+ +I + + E++N K +Q E + + +D+ + + + Q+ Q+ Sbjct: 453 KMQSQKVITL--SNEELNRQIKQVDQFWTEKYNNLSKQTKEDIYQLTQQYQMQLAQM--- 507 Query: 519 IDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEK 578 D NK I V + + QK + N ++S NK+I+ L +E + ++ ++ + Sbjct: 508 -DQTNKEKIYVIEQNHNQFLNSQKELFNV-QLSLLNKQILDLQKERENSIIQLDLMKVKL 565 Query: 579 GNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYD 638 LQ +++S + ++ + +M L ++ + ++++ Q +E++ LQ K D Sbjct: 566 NELQDKTQNFNSRDQRKDELMQN--QMATLKNSKEELLNVINQQNLAHKKEIYNLQTKID 623 Query: 639 EVEDKLADISQLQSDQVCSEIKSVHLE-EQIDALSASKKELALVIENLKLDKEQLYGTIK 697 +++ + D S + Q+ ++K LE +Q+ LS K +KE L Sbjct: 624 QLQQQY-DNSVREGKQIKEQLKLSQLEAQQVYNLSHQK------------NKESL----- 665 Query: 698 DLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKI 757 + + DK+ + KLQ+ + ++E + + + EL KI +E+++ +Q D ++ Sbjct: 666 NAQADKDSEIIKLQSELS-------RVETLYKQVVLEL--KIINEQKNDLQVID--DFQL 714 Query: 758 QERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEK-QKAYSEY 816 +E+D+ I N +S + + K ++ +L++ I +E + + +K Q +++ + Sbjct: 715 KEKDIEIGNQKSYILELKQKLQQLQKRINELELQLQNANKKLGQKDQEAKKEIENLNQRI 774 Query: 817 TIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHY 876 TIQ+ ++ D + E Q +E++ N+ L+++ ++ N++L I L +QQ Sbjct: 775 TIQKRQIQEERERC---DELAEAQEMEVQTWNERLKEQQKL----NEDLIIQLMRLQQQT 827 Query: 877 NALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQI 936 + N + + Q + L+ + + T + + K +I+ L+ +N Q+ Sbjct: 828 SQNSGLINELQNLKQQFEIVTNQYKQLQEDAEEATKQKSMV---KNVQIQMLQNHYNKQM 884 Query: 937 ESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLN----MNVEELNKMNLELIDKH 992 + + L + + N+ +LE + ++ I LN E+N++ + K Sbjct: 885 DVLTQQ---LEDMKQSNLNQ--KLEFPIMDFNVQIIALNDLLVKKNAEINQLKSQTQQKL 939 Query: 993 VQKQQT--QSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKL 1050 ++K Q +Y +Q ++E KL L + E ++ +N Q+ + + ++ + Sbjct: 940 LEKDSVIDQQREYAQQLLSEFEKLQVQLMDQHE----FQERADNLQM----INEEKDNSI 991 Query: 1051 AQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTE 1110 ++ +++E ++ K LD K E+ +++++Q IK+LK + NI + Sbjct: 992 IYLKEEIAKLKQE-NKLIKGKLDLK---EQSMVVIQDQQQLIKQLKIELQNKQKNIQPKQ 1047 Query: 1111 GMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQE 1170 I S + M + + + E +F+ E + + + E Sbjct: 1048 --IAVSHQQTMKSSIHRMSKRSESSRQEKSEVDWNGESQFLMENG--NNKLPCFHQQSSE 1103 Query: 1171 CYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAV-- 1228 +T +E +N+E+ ++ + Q++ L + L + + ++ ++++ S + Sbjct: 1104 SFTDNKLIEKMNSEIVDTNIRLRNQVDLLNQDKQSLQNDLTRTIQSLNQVKNENSELILK 1163 Query: 1229 ---DQRGFEIAELWKQHLAQREADFQKTEHELRV-----QLSAFESKYEQLLDSVQSSTQ 1280 Q+ E ++ ++ L +RE + QK + E+ + Q+++ Q L+++QSS Sbjct: 1164 LQYVQKALESSQQNQEKL-EREIN-QKKKKEINIVSFDDQINSKVKAMNQQLENLQSSKT 1221 Query: 1281 EETNKIVTMEQVTS-LQNKLQDKEEHLRNLQEKYADVINQI------EILRSEIEDEKVA 1333 ++T I ++Q S L ++ + R L+ K VIN++ +IL +++ ++ Sbjct: 1222 QQTQLINQLQQEHSELYQQIDRLNDQNRELR-KNITVINELNQTQEQQILELQMKLKQEQ 1280 Query: 1334 FXXXXXXXXXXXXXXXXDLRT-----ENQSYKQ--------MQEQSILNINEENAQLKKS 1380 D + ENQ KQ +QEQ+ L N EN Q KK+ Sbjct: 1281 LVTVKQNSEVRVFQLKQDQTSQIVSFENQQLKQQNVELQNKIQEQNQLISNYENQQQKKN 1340 Query: 1381 SXXXXXXX-----XXXXXRVNDAEAKVLELTHQ---LELKDSEIYQKTHEYTITLTQRND 1432 ++++ E + +L + + + +++ + +Y I + Q Sbjct: 1341 GLEKKYEEQQKQLSLYLDKIDNLENEKRQLEQEQNRIIMDSNKLLVRNEDYAIKVNQLEK 1400 Query: 1433 EFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKE 1479 ++ ++QQL E + + E Y ++ + + L+++ H +T + + Sbjct: 1401 TYQQLKQQLQEQQAQHEKQQYFQKEKNSNCNLRLNCQIFHCKTYKDQ 1447 Score = 128 bits (310), Expect = 9e-28 Identities = 254/1383 (18%), Positives = 592/1383 (42%), Gaps = 140/1383 (10%) Query: 305 EEKTEIEEKGSLEI---ANMTELTKKIELLEHLNCQIRQT---NKELENKLATMGTESKA 358 E KT+ ++ LE+ + +L ++I++ + L QI+Q N + + + + ++ Sbjct: 35 EVKTKNQQLSQLEMDYKGQVNQLQQQIQINQSLQLQIQQISQGNTDQKKAIEQLTDQNNQ 94 Query: 359 VSSPSKKGSPL--ISRKSGRNTASKMKSPWSQLSSETL----NQDTDKKINKNEIAKLEM 412 + + K+ I + + + + +L +E L N D+ ++ +I++L+ Sbjct: 95 LKNQLKQVQETNNIEKDQSKQNLERANTDIQKLKNEILQLQRNNDSLQQQKTYQISQLDT 154 Query: 413 ----VIQSLNKDLVDKEYVISEK-DTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIH 467 VI+ L + + + + K ++ D L+ ++ ++ + + + Sbjct: 155 NSKKVIEELQEQIRKMQLSATSKIESLTSELSLKNDQLDKLMKEINIKKNELYQSTANYE 214 Query: 468 V--GTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKN 525 T ++ + + ++Q++ +Q+ ND++ ++ A+ +ITQ+ EI KN Sbjct: 215 AVNATKSQQLIQAQQIQQKCQQDFNDKLAQFQLQ--------AQMKITQMEQEI--GQKN 264 Query: 526 MIKVKSNHKL--KLKQMQKTIDNFSKVSDSN-KEIVRLTEELHHLSQKV----AELEEEK 578 I K+N L K +++++ NF ++++ N K++ ++ ++ L + + + +K Sbjct: 265 TIIEKANQDLAKKAQEIKENNQNFEQINNQNQKKLQQMMIQVQKLQLAIESENTQYDRKK 324 Query: 579 GNLQLHLVDYDSGRMIE---SDVYKKMI--EMENLAETRL----------KAISLLESQK 623 G+L++ + + + ++ S+ Y + + E+ L L K++ L +++ Sbjct: 325 GDLKVQIDNLEKDLNMQQQSSNQYTQKLNNEINQLKNQNLDLQRQLSEKHKSLCLSQTES 384 Query: 624 FDLVQELHILQQKYD-EVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVI 682 +++L++ + E++ K + Q +S + ++ V +Q+ L ++E L+I Sbjct: 385 DAQIKQLNLQVASFQKEIQLKNQQLQQAESQLLEMKVLKVQEIDQM-KLKFDQREKELLI 443 Query: 683 ENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHE 742 +N +L+ + K + E++ +++ Q + + L K + E I +L + + Sbjct: 444 QNDQLNNNNKMQSQKVITLSNEELNRQIKQVDQFWTEKYNNLSKQTKEDIYQLTQQYQMQ 503 Query: 743 EQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQL 802 QT I++ N + EL + ++ L + I ++ R + + D + Sbjct: 504 LAQMDQTNKEKIYVIEQNHNQFLNSQKEL--FNVQLSLLNKQILDLQKERENSIIQLDLM 561 Query: 803 G---SYLQEKQKAYSEYTIQEDELV-NRLAVLMDHD----RVVEKQLLEIEHENKELQKK 854 + LQ+K + ++ ++DEL+ N++A L + V+ +Q L + E LQ K Sbjct: 562 KVKLNELQDKTQNFNSRDQRKDELMQNQMATLKNSKEELLNVINQQNLAHKKEIYNLQTK 621 Query: 855 NQILLEENQN-----------LQISLSDMQQHYNALVEKANRTDL-----AESESTKYQT 898 L ++ N L++S + QQ YN L + N+ L +SE K Q+ Sbjct: 622 IDQLQQQYDNSVREGKQIKEQLKLSQLEAQQVYN-LSHQKNKESLNAQADKDSEIIKLQS 680 Query: 899 QLRDLESNLKRITHEHQTLIVQKK--KEIEDLEI-EFNTQIESAIRDKKVLNEKYEKNIE 955 +L +E+ K++ E + + QK + I+D ++ E + +I + L +K ++ + Sbjct: 681 ELSRVETLYKQVVLELKIINEQKNDLQVIDDFQLKEKDIEIGNQKSYILELKQKLQQLQK 740 Query: 956 YVTQLEAQLQEYKNNI----ENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEI 1011 + +LE QLQ + + +E LN+ + + + +Q+++ + + E E+ Sbjct: 741 RINELELQLQNANKKLGQKDQEAKKEIENLNQ-RITIQKRQIQEERERCDELAEAQEMEV 799 Query: 1012 NKLNALLKQK---DEEIIALNQKINNAQVSYMSMVSDYESKLAQF---TTKLENMEEEMQ 1065 N LK++ +E++I ++ ++++ ++ QF T + + ++E+ + Sbjct: 800 QTWNERLKEQQKLNEDLIIQLMRLQQQTSQNSGLINELQNLKQQFEIVTNQYKQLQEDAE 859 Query: 1066 RVSKQLLDSKQHNEELQILVREQDDQIKEL-KETKLTFEMNI-PKTEGMIISSTIEPMSD 1123 +KQ S N ++Q+L + Q+ L ++ + + N+ K E I+ ++ ++ Sbjct: 860 EATKQ--KSMVKNVQIQMLQNHYNKQMDVLTQQLEDMKQSNLNQKLEFPIMDFNVQIIA- 916 Query: 1124 DANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQ---SAKLNTELQECYTKIIQLET 1180 ++ LK Q +++ +++ SV+ +Q + +L +E ++ +++ Sbjct: 917 ----LNDLLVKKNAEINQLKSQTQQKLLEKDSVIDQQREYAQQLLSEFEKLQVQLMDQHE 972 Query: 1181 LNTELTGHDVVNQEQINQ---LKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAE 1237 ++N+E+ N LK ++ +L EN L+ +L+ S V Q ++ + Sbjct: 973 FQERADNLQMINEEKDNSIIYLKEEIAKLKQEN-KLIKGKLDLKEQ-SMVVIQDQQQLIK 1030 Query: 1238 LWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQN 1297 K L ++ + Q + + Q +S ++ +SS QE++ E ++N Sbjct: 1031 QLKIELQNKQKNIQPKQIAVSHQ-QTMKSSIHRMSKRSESSRQEKSEVDWNGESQFLMEN 1089 Query: 1298 KLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQ 1357 + E + D IE + SEI D + DL Q Sbjct: 1090 GNNKLPCFHQQSSESFTD-NKLIEKMNSEIVDTNIRLRNQVDLLNQDKQSLQNDLTRTIQ 1148 Query: 1358 SYKQMQ-EQSILNINEENAQ-LKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSE 1415 S Q++ E S L + + Q +SS + E ++ Q+ K Sbjct: 1149 SLNQVKNENSELILKLQYVQKALESSQQNQEKLEREINQKKKKEINIVSFDDQINSKVKA 1208 Query: 1416 IYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLT---------------YEKESELA 1460 + Q+ + TQ+ ++Q+ E ++I+ L + E Sbjct: 1209 MNQQLENLQSSKTQQTQLINQLQQEHSELYQQIDRLNDQNRELRKNITVINELNQTQEQQ 1268 Query: 1461 ILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTN 1520 IL L+M T+++ SE+ +L ++ +I N+Q+ + N L+ ++ + N Sbjct: 1269 ILELQMKLKQEQLVTVKQNSEVRVFQLKQDQTSQIVSFE--NQQLKQQNVELQNKIQEQN 1326 Query: 1521 EMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKEL 1580 ++ + ENQ+ + L + Q + KI D + QL+ N+ + Sbjct: 1327 QLISNYENQQQKKNGLEKKYEEQQKQLSLYLDKI--------DNLENEKRQLEQEQNRII 1378 Query: 1581 LDA 1583 +D+ Sbjct: 1379 MDS 1381 Score = 102 bits (245), Expect = 7e-20 Identities = 180/932 (19%), Positives = 397/932 (42%), Gaps = 82/932 (8%) Query: 678 LALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLA 737 L I++L+ + + + LE D + +N+LQ IQ N L +++++S + A Sbjct: 25 LEFEIKSLQNEVKTKNQQLSQLEMDYKGQVNQLQQQIQINQSLQLQIQQISQGNTDQKKA 84 Query: 738 KINHEEQS-KIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLE 796 +Q+ +++ Q ++QE + NIE + SK + R I +++ L+ Sbjct: 85 IEQLTDQNNQLKNQL---KQVQETN----NIEKDQSK--QNLERANTDIQKLKNEILQLQ 135 Query: 797 RKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLL---EIEHENKELQK 853 R D L Q+K S+ +++ L +++ + QL +IE EL Sbjct: 136 RNNDSLQ---QQKTYQISQLDTNSKKVIEEL-----QEQIRKMQLSATSKIESLTSELSL 187 Query: 854 KNQILLEENQNLQISLSDMQQHYNALVEKANRT---DLAESESTKYQTQLRDLESNLKRI 910 KN L + + + I +++ Q A E N T L +++ + + Q +D L + Sbjct: 188 KNDQLDKLMKEINIKKNELYQS-TANYEAVNATKSQQLIQAQQIQQKCQ-QDFNDKLAQF 245 Query: 911 THEHQTLIVQKKKEI--EDLEIE-FNTQIESAIRDKKVLNEKYEK----NIEYVTQLEAQ 963 + Q I Q ++EI ++ IE N + ++ K N+ +E+ N + + Q+ Q Sbjct: 246 QLQAQMKITQMEQEIGQKNTIIEKANQDLAKKAQEIKENNQNFEQINNQNQKKLQQMMIQ 305 Query: 964 LQEYKNNIENLNMNVEELN---KMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQ 1020 +Q+ + IE+ N + K+ ++ ++K + QQ S YT++ NEIN+L Sbjct: 306 VQKLQLAIESENTQYDRKKGDLKVQIDNLEKDLNMQQQSSNQYTQKLNNEINQLKNQNLD 365 Query: 1021 KDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHN-E 1079 ++ ++ + +Q + + ++A F +++ +++Q+ QLL+ K + Sbjct: 366 LQRQLSEKHKSLCLSQTESDAQIKQLNLQVASFQKEIQLKNQQLQQAESQLLEMKVLKVQ 425 Query: 1080 ELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXX 1139 E+ + + D + KEL N +I+ + E ++ VD Sbjct: 426 EIDQMKLKFDQREKELLIQNDQLNNNNKMQSQKVITLSNEELNRQIKQVD---QFWTEKY 482 Query: 1140 XXLKVQEEEEFIQERSVLQEQSAKLN-TELQECYTKIIQLETLNTELTGHDVVNQEQINQ 1198 L Q +E+ Q Q Q A+++ T ++ Y +I+ + N L + Q++ Sbjct: 483 NNLSKQTKEDIYQLTQQYQMQLAQMDQTNKEKIY--VIE-QNHNQFLNSQKELFNVQLSL 539 Query: 1199 LKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELR 1258 L ++ L E +N + + ++ ++ D+ Q+ R+ Q+ + ++ Sbjct: 540 LNKQILDLQKERENSIIQLDLMKVKLNELQDK---------TQNFNSRD---QRKDELMQ 587 Query: 1259 VQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVIN 1318 Q++ ++ E+LL+ + + +++ +LQ K+ ++ N + + Sbjct: 588 NQMATLKNSKEELLNVINQ------QNLAHKKEIYNLQTKIDQLQQQYDNSVREGKQIKE 641 Query: 1319 QIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXD-----LRTENQSYKQMQEQSILNINEE 1373 Q+++ S++E ++V D L++E + + +Q +L + Sbjct: 642 QLKL--SQLEAQQVYNLSHQKNKESLNAQADKDSEIIKLQSELSRVETLYKQVVLELKII 699 Query: 1374 NAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDE 1433 N Q + + ++ +LEL +L+ ++ ++ +E + L N Sbjct: 700 NEQKNDLQVIDDFQLKEKDIEIGNQKSYILELKQKLQ----QLQKRINELELQLQNAN-- 753 Query: 1434 FENVRQQLVEYEKRIEDLTYE---KESELAILRLKMHENANHYETMQKESEIERVKLIEE 1490 + + Q+ E +K IE+L ++ ++ R + E A E M+ ++ ER+K ++ Sbjct: 754 -KKLGQKDQEAKKEIENLNQRITIQKRQIQEERERCDELAEAQE-MEVQTWNERLKEQQK 811 Query: 1491 LNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVR-A 1549 LN + + +Q N L E+ + + NQ ++ +E T ++MV+ Sbjct: 812 LNEDLIIQLMRLQQQTSQNSGLINELQNLKQQFEIVTNQYKQLQEDAEEATKQKSMVKNV 871 Query: 1550 SSSKIQKHVSFASDT-KQGRDEQLDNTMNKEL 1580 +Q H + D Q ++ + +N++L Sbjct: 872 QIQMLQNHYNKQMDVLTQQLEDMKQSNLNQKL 903 Score = 72.9 bits (171), Expect = 7e-11 Identities = 111/580 (19%), Positives = 254/580 (43%), Gaps = 57/580 (9%) Query: 1008 INEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRV 1067 +N+ N+L +K E+ NQ+++ ++ Y V+ + ++ Q ++++ ++Q++ Sbjct: 19 LNKNNRLEFEIKSLQNEVKTKNQQLSQLEMDYKGQVNQLQQQI-QIN---QSLQLQIQQI 74 Query: 1068 SKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANN 1127 S+ D K+ E+L + +Q+K+++ET NI K + +E + D Sbjct: 75 SQGNTDQKKAIEQLTDQNNQLKNQLKQVQETN-----NIEKDQS---KQNLERANTDIQK 126 Query: 1128 VDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTE-LT 1186 + L+ Q+ + Q L S K+ ELQE K+ T E LT Sbjct: 127 LKNEILQLQRNNDSLQQQKTYQISQ----LDTNSKKVIEELQEQIRKMQLSATSKIESLT 182 Query: 1187 GHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQR 1246 + +Q+++L ++++N + + L + A ++++ Q+ + ++ Q Q+ Sbjct: 183 SELSLKNDQLDKL---MKEINIKKNELYQSTANY-EAVNATKSQQLIQAQQI--QQKCQQ 236 Query: 1247 EADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHL 1306 + + + + +L+ Q+ ++ EQ + +++ E+ N+ + ++ ++ Q+ E+ Sbjct: 237 DFNDKLAQFQLQAQMKI--TQMEQEIGQ-KNTIIEKANQDLA-KKAQEIKENNQNFEQIN 292 Query: 1307 RNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQS 1366 Q+K ++ Q++ L+ IE E + DL + QS Q ++ Sbjct: 293 NQNQKKLQQMMIQVQKLQLAIESENTQYDRKKGDLKVQIDNLEKDLNMQQQSSNQYTQK- 351 Query: 1367 ILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTIT 1426 +N E QLK + D + ++ E L L +E + + + Sbjct: 352 ---LNNEINQLKNQNL--------------DLQRQLSEKHKSLCLSQTESDAQIKQLNLQ 394 Query: 1427 LTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVK 1486 + E + QQL + E ++ ++ K E+ ++LK + E + + ++ Sbjct: 395 VASFQKEIQLKNQQLQQAESQLLEMKVLKVQEIDQMKLKFDQREK--ELLIQNDQLNNNN 452 Query: 1487 LIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNM 1546 ++ V + LN+Q+ ++++ E+ ++ QT ++I +T ++ L M Sbjct: 453 KMQSQKVITLSNEELNRQIKQVDQFWTEKYNNLSK-QT---KEDIYQLTQQYQM-QLAQM 507 Query: 1547 VRASSSKI----QKHVSFASDTKQGRDEQLDNTMNKELLD 1582 + + KI Q H F + K+ + QL + +NK++LD Sbjct: 508 DQTNKEKIYVIEQNHNQFLNSQKELFNVQL-SLLNKQILD 546 >UniRef50_Q23DA0 Cluster: Putative uncharacterized protein; n=1; Tetrahymena thermophila SB210|Rep: Putative uncharacterized protein - Tetrahymena thermophila SB210 Length = 1404 Score = 139 bits (337), Expect = 5e-31 Identities = 237/1121 (21%), Positives = 491/1121 (43%), Gaps = 129/1121 (11%) Query: 473 EDVNEIAKVQEQLKQELNDEIKDVNVK----DLIEKLKS-------AEEQITQLNDEIDA 521 E +N + ++ E Q L D I+DV K DLI+ +K +++ +L +EI Sbjct: 61 ERINSMRELYEMRFQTLQDTIRDVYEKIIKDDLIQTMKDNPISQEYIHQRVRELFEEIVL 120 Query: 522 ANKNMIKVKSNHKLKLKQMQKTIDNFSKV-SDSNKEIVRLTEELHHLSQKVAELEE---- 576 + + +I K + + + + FSK+ ++ KE+ + EE+ ++ + L+E Sbjct: 121 SEREVIIDKLSSQYTFLKAE-----FSKLENEKRKELQQHDEEMEESARIINMLKEDLHK 175 Query: 577 EKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQK 636 E+ N Q + ++ + ++V ++ + L + K LE ++ ++Q L QK Sbjct: 176 ERQNRQFYEQEFQRMQKKMNEVTEQFEDA--LIKKEQKMQDKLEQEQNQVIQ----LTQK 229 Query: 637 YDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLD--KEQLYG 694 ++++E + + + Q+ Q+ SE + + ++ S+K+L L + L+ ++++ Sbjct: 230 FNDLEKEYEQLIKSQN-QIFSENQELKQRGELMKADLSEKQLELNTYKIDLNTAEDKIKQ 288 Query: 695 TIKDLENDKEDIMNKLQNY---IQENMDLTDKLE--KMSAEKI-SELLAKINHEEQSKIQ 748 +K +N K ++ Y ++EN L +LE K+ A I +++ K H +Q+ + Sbjct: 289 QLKLNDNLKLEVSQLSSRYNQLMEENTHLNMELENTKLDATTIENQMQQKFQHAQQNLQK 348 Query: 749 TQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQE 808 Q ++ Q+ +E ++++ +YK R E+ I + K DQ +E Sbjct: 349 GQEYLEKVKQKNKQKLEAYKNKIIEYKQRNQEAEQIIRQL---------KQDQN----EE 395 Query: 809 KQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQIS 868 K+K+ L + +R++++ +E E + +E+ +Q+ +ENQ Sbjct: 396 KEKSQKS--------------LQNWERILQETKIEYERKIEEIHNVSQMKFDENQRRHDE 441 Query: 869 -LSDMQQHY----NALVEKANRTDLAESESTKYQT-QLRD-LESNLKRITHE------HQ 915 L ++Q HY N ++ E + +YQ QL+ LE L ++ + H Sbjct: 442 YLQELQLHYQETMNQKIDDIKNESNLEIDQLRYQERQLKQMLEEKLNQLQKDYISKSLHD 501 Query: 916 TLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYE--KNIEYVTQLEA----------- 962 ++ +KKK I+ ++ +F+ + ++ ++ NE+ E KN E+ QL Sbjct: 502 EIMDEKKKSIDKMKQDFDHFLSEFKKETEMKNEQIELRKNKEHEQQLAYLQSNFFFDYFY 561 Query: 963 -QLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQK 1021 Q + +K+ +NL E L + L+ + +Q + Q D ++ I ++ + Sbjct: 562 NQFKSFKSKSDNLKELEESLREYKLQ--GRELQSKNEQLEDQQQKIIADLENQIKQNRIY 619 Query: 1022 DEEIIALNQKIN---NAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHN 1078 + EI L +K+N N + D + AQ + LE+ +QR S+ L + N Sbjct: 620 ESEIQRLQEKLNKQKNKNNELQKTLDDLDQLSAQLKSDLESSRSTIQRYSQDLENITVQN 679 Query: 1079 EELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXX 1138 E+L + EQ + K +L ++ KTE I+ + N+ Sbjct: 680 EKLFAQINEQ-----KQKNAELIGSVSNLKTEVSNGQQVIQFKEEVIKNIKENLEELKQE 734 Query: 1139 XXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQ 1198 L + + + +E++ E +K +E T+I +L+ E + + Q++ Sbjct: 735 NKQLNTKFFDLY-KEKAQKNEDESK---RFEEINTQITRLQYEAQEKAHQSEILKSQLDT 790 Query: 1199 LKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELR 1258 + + + L E L + E + IS A + E+ L+ + L Q++ + ++EL Sbjct: 791 ISEQKKILEEEIQYLKIDLLE-KERISQASLREKLELENLFSKKLQQQKELKYQIKNELT 849 Query: 1259 VQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRN-LQEKYADVI 1317 ++L+ Q+ + VQ + ++N+I V S+Q K +D N LQEK V Sbjct: 850 IELTRLRKDLSQIQEFVQHQIKMKSNEIELW--VKSIQGKSKDILNKQNNQLQEKLQIVE 907 Query: 1318 NQI-EILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQ 1376 N+I +I+D K F DL+ + + + + +++ N Sbjct: 908 NEISRECEEQIQDYKHRF-----------EQEISDLQQQKEREIKQLSDYVNKLSQANQD 956 Query: 1377 LKKSSXXXXXXXXXXXXRVN--DAEAKVLELTHQLELKDSEIYQKTHEYTIT-LTQRNDE 1433 L S + + + + L+ ++ +K SE ++T + ++ QR +E Sbjct: 957 LINESKGYQEELNELKNQYDLLQQQNQNLQKSYDNAIKKSEQMEQTFDLRLSEYQQRKEE 1016 Query: 1434 FENVRQQLVEYEKRI--EDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEEL 1491 R+Q+VE E I E++ K ++ +M++N ++ Q+E E+E V+ Sbjct: 1017 SGLKRKQMVERELDIANEEIIQWKNKYQNLID-QMNKNVEQMQS-QREIEVETVRQKMNF 1074 Query: 1492 NVKITES--VSLNKQVAELNKALEEEVAKTNEMQTALENQE 1530 +++ ES L + EL +L ++ K N +Q ++ +E Sbjct: 1075 SIQQLESQIEMLQQNELELRDSLAKQNDKINLLQKIIQEKE 1115 Score = 116 bits (278), Expect = 7e-24 Identities = 214/1114 (19%), Positives = 482/1114 (43%), Gaps = 99/1114 (8%) Query: 473 EDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSN 532 E++ E A++ LK++L+ E ++ + ++ + ++++ ++ ++ + A +IK + Sbjct: 157 EEMEESARIINMLKEDLHKERQNRQFYE--QEFQRMQKKMNEVTEQFEDA---LIKKEQK 211 Query: 533 HKLKLKQMQKTIDNFS-KVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSG 591 + KL+Q Q + + K +D KE +L + + + + EL++ ++ L S Sbjct: 212 MQDKLEQEQNQVIQLTQKFNDLEKEYEQLIKSQNQIFSENQELKQRGELMKADL----SE 267 Query: 592 RMIESDVYKKMIEMENLAETRLKA-ISLLESQKFDLVQELHILQQKYDEVEDKLADIS-Q 649 + +E + YK I++ N AE ++K + L ++ K ++ Q L +Y+++ ++ ++ + Sbjct: 268 KQLELNTYK--IDL-NTAEDKIKQQLKLNDNLKLEVSQ----LSSRYNQLMEENTHLNME 320 Query: 650 LQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNK 709 L++ ++ + ++++ + ++ +E +K +Q K+ + + + Sbjct: 321 LENTKLDATTIENQMQQKFQHAQQNLQKGQEYLEKVKQKNKQKLEAYKNKIIEYKQRNQE 380 Query: 710 LQNYIQE-NMDLTDKLEKM--SAEKISELLAKINHEEQSKIQ-----TQFGIDAKIQERD 761 + I++ D ++ EK S + +L + E + KI+ +Q D + D Sbjct: 381 AEQIIRQLKQDQNEEKEKSQKSLQNWERILQETKIEYERKIEEIHNVSQMKFDENQRRHD 440 Query: 762 LYIENIESELSK-YKSRICRLE-ESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQ 819 Y++ ++ + +I ++ ES ++ RY + L L + QK Y ++ Sbjct: 441 EYLQELQLHYQETMNQKIDDIKNESNLEIDQLRYQERQLKQMLEEKLNQLQKDYISKSLH 500 Query: 820 EDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQH---- 875 DE+++ +D + L E + + K QI L +N+ + L+ +Q + Sbjct: 501 -DEIMDEKKKSIDKMKQDFDHFLS-EFKKETEMKNEQIELRKNKEHEQQLAYLQSNFFFD 558 Query: 876 --YNALVEKANRTD-LAESEST--KYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEI 930 YN +++D L E E + +Y+ Q R+L+S +++ + Q +I + +I+ I Sbjct: 559 YFYNQFKSFKSKSDNLKELEESLREYKLQGRELQSKNEQLEDQQQKIIADLENQIKQNRI 618 Query: 931 -EFNTQ-IESAIRDKKVLNEKYEKNIEYVTQLEAQL-----------QEYKNNIENLNMN 977 E Q ++ + +K N + +K ++ + QL AQL Q Y ++EN+ + Sbjct: 619 YESEIQRLQEKLNKQKNKNNELQKTLDDLDQLSAQLKSDLESSRSTIQRYSQDLENITVQ 678 Query: 978 VEELNKMNLELIDKHVQKQQTQSPDYTEQYINE--INKLNALLKQKDEEIIALNQKINNA 1035 E+L E K+ + + S TE + I ++K E + L Q+ Sbjct: 679 NEKLFAQINEQKQKNAELIGSVSNLKTEVSNGQQVIQFKEEVIKNIKENLEELKQENKQL 738 Query: 1036 QVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKEL 1095 + + + K + + E + ++ R+ + + +E L+ + +Q K L Sbjct: 739 NTKFFDLYKEKAQKNEDESKRFEEINTQITRLQYEAQEKAHQSEILKSQLDTISEQKKIL 798 Query: 1096 KETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERS 1155 +E ++++ + E + +S E + ++ LK Q + E E + Sbjct: 799 EEEIQYLKIDLLEKERISQASLREKLE-----LENLFSKKLQQQKELKYQIKNELTIELT 853 Query: 1156 VLQEQSAKLNTELQ---ECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTE--- 1209 L++ +++ +Q + + I+L + + D++N++ NQL+ KL+ + E Sbjct: 854 RLRKDLSQIQEFVQHQIKMKSNEIELWVKSIQGKSKDILNKQN-NQLQEKLQIVENEISR 912 Query: 1210 --NDNLLSTVAELRSSISSAVDQRGFEIAEL--WKQHLAQREADFQKTEHELRVQLSAFE 1265 + + IS Q+ EI +L + L+Q D + +L+ + Sbjct: 913 ECEEQIQDYKHRFEQEISDLQQQKEREIKQLSDYVNKLSQANQDLINESKGYQEELNELK 972 Query: 1266 SKYEQLLD---SVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEI 1322 ++Y+ L ++Q S K MEQ L+ + + L+ K V +++I Sbjct: 973 NQYDLLQQQNQNLQKSYDNAIKKSEQMEQTFDLRLSEYQQRKEESGLKRKQM-VERELDI 1031 Query: 1323 LRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSX 1382 EI K + + N++ +QMQ Q + + E + K + Sbjct: 1032 ANEEIIQWKNKYQNL--------------IDQMNKNVEQMQSQREIEV--ETVRQKMNFS 1075 Query: 1383 XXXXXXXXXXXRVNDAEAK--VLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQ 1440 + N+ E + + + ++ L I +K + +++ + ++V + Sbjct: 1076 IQQLESQIEMLQQNELELRDSLAKQNDKINLLQKIIQEKEEAFEGLRREKDQQIKSVTEV 1135 Query: 1441 LVEYEKRIEDLTYEKESELAILRLKMHENANHY--ETMQKESEIERVKLIEELNVKITES 1498 +EY+ + E L +K+S ILR + E NH+ E S+I +LIEE + I ++ Sbjct: 1136 ELEYKLKEEGLRKQKKSYDEILR-EQEEKINHFVNEITILNSKIN--QLIEEKTILINKN 1192 Query: 1499 VSLNKQVAELNKALEEEVAKTNEMQTALENQEIE 1532 L Q+ +L ++ ++AK + N+EIE Sbjct: 1193 KDLQFQL-DLKQSQLNQLAKEFHDKQTKSNKEIE 1225 Score = 108 bits (259), Expect = 1e-21 Identities = 186/1034 (17%), Positives = 431/1034 (41%), Gaps = 62/1034 (5%) Query: 212 EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLE-EANKLLEAARFEISLE 270 E +Q+ K Q + E K + + D+ K + +++ + + N + + ++ L Sbjct: 234 EKEYEQLIKSQNQIFSENQELKQRGELMKADLSEKQLELNTYKIDLNTAEDKIKQQLKL- 292 Query: 271 HSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTE-LTKKIE 329 + L E+ Q L +E + + T IE + + + + L K E Sbjct: 293 NDNLKLEVSQLSSRYNQLMEENTHL-NMELENTKLDATTIENQMQQKFQHAQQNLQKGQE 351 Query: 330 LLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQL 389 LE + + +Q + +NK+ ++ ++ + + + K W ++ Sbjct: 352 YLEKVKQKNKQKLEAYKNKIIEYKQRNQEAEQIIRQLKQ--DQNEEKEKSQKSLQNWERI 409 Query: 390 SSETLNQDTDKKINK-NEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTL 448 ET + ++KI + + +++++ D +E + ++T + Sbjct: 410 LQET-KIEYERKIEEIHNVSQMKFDENQRRHDEYLQELQLHYQETMNQKIDDIKNESNLE 468 Query: 449 IAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSA 508 I QL+ + +Q + E +N++ K + + + L+DEI D K + + + Sbjct: 469 IDQLRYQERQLKQ--------MLEEKLNQLQK--DYISKSLHDEIMDEKKKSIDKMKQDF 518 Query: 509 EEQITQLNDEIDAANKNM-IKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHL 567 + +++ E + N+ + ++ H+ +L +Q F + K ++ L L Sbjct: 519 DHFLSEFKKETEMKNEQIELRKNKEHEQQLAYLQSNFF-FDYFYNQFKSFKSKSDNLKEL 577 Query: 568 SQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLV 627 + + E + + LQ +E K + ++EN ++K + ES+ L Sbjct: 578 EESLREYKLQGRELQ------SKNEQLEDQQQKIIADLEN----QIKQNRIYESEIQRLQ 627 Query: 628 QELHILQQKYDEVEDKLADI----SQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIE 683 ++L+ + K +E++ L D+ +QL+SD S + ++ ++ ++L I Sbjct: 628 EKLNKQKNKNNELQKTLDDLDQLSAQLKSDLESSRSTIQRYSQDLENITVQNEKLFAQIN 687 Query: 684 NLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEE 743 K +L G++ +L+ + + +Q + ++ + LE++ E +L K Sbjct: 688 EQKQKNAELIGSVSNLKTEVSNGQQVIQFKEEVIKNIKENLEELKQEN-KQLNTKFFDLY 746 Query: 744 QSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLG 803 + K Q + +E + I ++ E + + L+ + + +++ LE + L Sbjct: 747 KEKAQKNEDESKRFEEINTQITRLQYEAQEKAHQSEILKSQLDTISEQKKILEEEIQYLK 806 Query: 804 SYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLL-EIEHENKELQKK-NQILLEE 861 L EK++ ++ EL N + + + ++ Q+ E+ E L+K +QI Sbjct: 807 IDLLEKERISQASLREKLELENLFSKKLQQQKELKYQIKNELTIELTRLRKDLSQIQEFV 866 Query: 862 NQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEH-QTLIVQ 920 +++ ++++ ++ K+ D+ ++ + Q +L+ +E+ + R E Q + Sbjct: 867 QHQIKMKSNEIELWVKSIQGKSK--DILNKQNNQLQEKLQIVENEISRECEEQIQDYKHR 924 Query: 921 KKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEE 980 ++EI DL+ + +I+ L++ + I + +L E KN + L + Sbjct: 925 FEQEISDLQQQKEREIKQLSDYVNKLSQANQDLINESKGYQEELNELKNQYDLLQQQNQN 984 Query: 981 LNKMNLELIDKHVQKQQT---QSPDYTEQYINEINKLNALLKQK----DEEIIALNQKIN 1033 L K I K Q +QT + +Y ++ K +++++ +EEII K Sbjct: 985 LQKSYDNAIKKSEQMEQTFDLRLSEYQQRKEESGLKRKQMVERELDIANEEIIQWKNKYQ 1044 Query: 1034 NAQVSYMSMVSDYESKLA-QFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQI 1092 N V +S+ + T + M +Q++ Q+ +Q+ EL+ + +Q+D+I Sbjct: 1045 NLIDQMNKNVEQMQSQREIEVETVRQKMNFSIQQLESQIEMLQQNELELRDSLAKQNDKI 1104 Query: 1093 ----KELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEE 1148 K ++E + FE + + + I S E + + L+ QEE+ Sbjct: 1105 NLLQKIIQEKEEAFE-GLRREKDQQIKSVTEVELEYKLKEEGLRKQKKSYDEILREQEEK 1163 Query: 1149 --EFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQL 1206 F+ E ++L ++K+N ++E I + + L +L + Q Q+NQL + Sbjct: 1164 INHFVNEITIL---NSKINQLIEEKTILINKNKDLQFQLD----LKQSQLNQLAKEFHDK 1216 Query: 1207 NTENDNLLSTVAEL 1220 T+++ + + +L Sbjct: 1217 QTKSNKEIEDLHKL 1230 Score = 99 bits (238), Expect = 5e-19 Identities = 173/969 (17%), Positives = 407/969 (42%), Gaps = 88/969 (9%) Query: 651 QSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYG---TIKDLENDKEDIM 707 Q QV S +S + + ++++ ++ A I +EQL I+D+E D + + Sbjct: 4 QEFQVSSPQQSETMNTGLSNINSADQQHAFRINQYFQGQEQLLDQQINIQDVEMDYNERI 63 Query: 708 NKLQNYIQENMD-----LTDKLEKMSAEKISELLAK--INHEEQSKIQTQFGIDAKIQER 760 N ++ + + D EK+ + + + + I+ E + + + + ER Sbjct: 64 NSMRELYEMRFQTLQDTIRDVYEKIIKDDLIQTMKDNPISQEYIHQRVRELFEEIVLSER 123 Query: 761 DLYIENIESELSKYKSRICRLE-ESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQ 819 ++ I+ + S+ + K+ +LE E ++ +E A + ++ K Sbjct: 124 EVIIDKLSSQYTFLKAEFSKLENEKRKELQQHDEEMEESARIINMLKEDLHKERQNRQFY 183 Query: 820 EDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQIS--LSDMQQHYN 877 E E + + E L++ KE + ++++ E+NQ +Q++ +D+++ Y Sbjct: 184 EQEFQRMQKKMNEVTEQFEDALIK-----KEQKMQDKLEQEQNQVIQLTQKFNDLEKEYE 238 Query: 878 ALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIE 937 L++ N+ +E++ K + +L ++++L +K+ E+ +I+ NT E Sbjct: 239 QLIKSQNQI-FSENQELKQRGEL--MKADLS-----------EKQLELNTYKIDLNTA-E 283 Query: 938 SAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQ 997 I+ + LN+ + + ++ QL E EN ++N+E N +L ++ Q Sbjct: 284 DKIKQQLKLNDNLKLEVSQLSSRYNQLME-----ENTHLNME---LENTKLDATTIENQM 335 Query: 998 TQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKL 1057 Q + +Q + + + +KQK+++ + + N + Y + E + Q Sbjct: 336 QQKFQHAQQNLQKGQEYLEKVKQKNKQKL---EAYKNKIIEYKQRNQEAEQIIRQLK--- 389 Query: 1058 ENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISST 1117 ++ EE ++ K L + ++ +E +I + ++I + + K F+ N + + + Sbjct: 390 QDQNEEKEKSQKSLQNWERILQETKIEYERKIEEIHNVSQMK--FDENQRRHDEYLQELQ 447 Query: 1118 IEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQ 1177 + +D L+ QE Q + +L+E KLN ++ +K + Sbjct: 448 LHYQETMNQKIDDIKNESNLEIDQLRYQER----QLKQMLEE---KLNQLQKDYISKSLH 500 Query: 1178 LETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNL-LSTVAELRSSISSAVDQRGFEIA 1236 E ++ + D + Q+ + L ++ +N+ + L E ++ F+ Sbjct: 501 DEIMDEKKKSIDKMKQDFDHFLSEFKKETEMKNEQIELRKNKEHEQQLAYLQSNFFFDYF 560 Query: 1237 ELWKQHLAQREADFQKTEHELR---VQLSAFESKYEQLLDSVQSSTQEETNKI----VTM 1289 + + + ++ E LR +Q +SK EQL D Q + N+I + Sbjct: 561 YNQFKSFKSKSDNLKELEESLREYKLQGRELQSKNEQLEDQQQKIIADLENQIKQNRIYE 620 Query: 1290 EQVTSLQNKLQDKEEHLRNLQEKYADVINQIEI-LRSEIEDEKVAFXXXXXXXXXXXXXX 1348 ++ LQ KL +K+++ N +K D ++Q+ L+S++E + Sbjct: 621 SEIQRLQEKL-NKQKNKNNELQKTLDDLDQLSAQLKSDLESSR--------STIQRYSQD 671 Query: 1349 XXDLRTENQS-YKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTH 1407 ++ +N+ + Q+ EQ ++NA+L S + E + + Sbjct: 672 LENITVQNEKLFAQINEQK-----QKNAELIGSVSNLKTEVSNGQQVIQFKEEVIKNIKE 726 Query: 1408 QLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYE---KESELAILRL 1464 LE E Q ++ ++ + E+ ++ E +I L YE K + IL+ Sbjct: 727 NLEELKQENKQLNTKFFDLYKEKAQKNEDESKRFEEINTQITRLQYEAQEKAHQSEILKS 786 Query: 1465 KMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQT 1524 ++ + + +++E + ++ L+E+ + SL +++ EL +++ + E++ Sbjct: 787 QLDTISEQKKILEEEIQYLKIDLLEKERIS---QASLREKL-ELENLFSKKLQQQKELKY 842 Query: 1525 ALENQ-EIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDA 1583 ++N+ IE+ L +++ +Q V+ + + QG+ + + N N +L + Sbjct: 843 QIKNELTIELTRLRKDLSQIQEFVQHQIKMKSNEIELWVKSIQGKSKDILNKQNNQLQEK 902 Query: 1584 VPRAELDLA 1592 + E +++ Sbjct: 903 LQIVENEIS 911 Score = 97.5 bits (232), Expect = 3e-18 Identities = 169/816 (20%), Positives = 345/816 (42%), Gaps = 77/816 (9%) Query: 331 LEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLS 390 ++ L Q RQ + LE KL + K S S + +K + KMK + Sbjct: 469 IDQLRYQERQLKQMLEEKLNQL---QKDYISKSLHDEIMDEKKK---SIDKMKQDFDHFL 522 Query: 391 SETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIA 450 SE ++T+ K + E+ K + Q L + + D D L Sbjct: 523 SE-FKKETEMKNEQIELRKNKEHEQQLA--YLQSNFFF---DYFYNQFKSFKSKSDNLKE 576 Query: 451 QLQLEHQQHMEGPSLIHVGTNTEDVNE--IAKVQEQLKQELNDEIKDVNVKDLIEKLKSA 508 + + ++G L ED + IA ++ Q+KQ + I + ++ L EKL Sbjct: 577 LEESLREYKLQGRELQSKNEQLEDQQQKIIADLENQIKQ---NRIYESEIQRLQEKLNKQ 633 Query: 509 EEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLS 568 + + +L +D ++ ++KS+ + +Q+ + ++ N+ +L +++ Sbjct: 634 KNKNNELQKTLDDLDQLSAQLKSDLESSRSTIQRYSQDLENITVQNE---KLFAQINEQK 690 Query: 569 QKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQ 628 QK AEL NL+ + + + +V K + ENL E + + L ++ FDL + Sbjct: 691 QKNAELIGSVSNLKTEVSNGQQVIQFKEEVIKNI--KENLEELKQEN-KQLNTKFFDLYK 747 Query: 629 ELHILQQKYDE---VEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENL 685 E Q+ DE E+ I++LQ + +S L+ Q+D +S KK L I+ L Sbjct: 748 EK--AQKNEDESKRFEEINTQITRLQYEAQEKAHQSEILKSQLDTISEQKKILEEEIQYL 805 Query: 686 KLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQS 745 K+D + + +K ++ N +Q+ +L +++ +++ L ++ + Q Sbjct: 806 KIDLLEKERISQASLREKLELENLFSKKLQQQKELKYQIKNELTIELTRLRKDLS-QIQE 864 Query: 746 KIQTQFGIDAKIQERDLYIENIESELSKYKSRIC-RLEESIAVME------------DRR 792 +Q Q I K E +L++++I+ + ++ +L+E + ++E D + Sbjct: 865 FVQHQ--IKMKSNEIELWVKSIQGKSKDILNKQNNQLQEKLQIVENEISRECEEQIQDYK 922 Query: 793 YSLERKADQLGSYLQEKQKAYSEYTIQ----EDELVNRLAVLMDHDRVVEKQLLEIEHEN 848 + E++ L + + K S+Y + +L+N + ++ Q ++ +N Sbjct: 923 HRFEQEISDLQQQKEREIKQLSDYVNKLSQANQDLINESKGYQEELNELKNQYDLLQQQN 982 Query: 849 KELQKK--NQILLEEN--QNLQISLSDMQQHY--NALVEKA---NRTDLAESE----STK 895 + LQK N I E Q + LS+ QQ + L K D+A E K Sbjct: 983 QNLQKSYDNAIKKSEQMEQTFDLRLSEYQQRKEESGLKRKQMVERELDIANEEIIQWKNK 1042 Query: 896 YQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIE 955 YQ + + N++++ + + + ++++ + +QIE +++ L + K + Sbjct: 1043 YQNLIDQMNKNVEQMQSQREIEVETVRQKMNFSIQQLESQIEMLQQNELELRDSLAKQND 1102 Query: 956 YVTQLEAQLQEYKNNIENL----NMNVEELNKMNLE--LIDKHVQKQQ-------TQSPD 1002 + L+ +QE + E L + ++ + ++ LE L ++ ++KQ+ + + Sbjct: 1103 KINLLQKIIQEKEEAFEGLRREKDQQIKSVTEVELEYKLKEEGLRKQKKSYDEILREQEE 1162 Query: 1003 YTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEE 1062 ++NEI LN+ + Q EE L K + Q S +F K + Sbjct: 1163 KINHFVNEITILNSKINQLIEEKTILINKNKDLQFQLDLKQSQLNQLAKEFHDKQTKSNK 1222 Query: 1063 EMQRVSKQLLDSKQH---NEELQILVREQDDQIKEL 1095 E++ + K L S ++ N E L R+ D++ + L Sbjct: 1223 EIEDLHKLLTQSFKNMNDNSENIDLARKLDEETRLL 1258 Score = 51.2 bits (117), Expect = 2e-04 Identities = 127/638 (19%), Positives = 264/638 (41%), Gaps = 67/638 (10%) Query: 147 LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXX 206 +SN E N V+Q K E I +++E + E Q + N Sbjct: 700 VSNLKTEVSNGQQVIQFK----EEVIKNIKENLEELKQENKQLNTKFFDLYKEKAQKNED 755 Query: 207 XXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFE 266 E+ Q+T++Q EA+ K + +LK ++ ++ E K+LE Sbjct: 756 ESKRFEEINTQITRLQ-----YEAQEKAHQSEILKS------QLDTISEQKKILEE---- 800 Query: 267 ISLEHSKL-AQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELT 325 +++ K+ E E+ L + ++ E K +I+ + ++E+ + + Sbjct: 801 -EIQYLKIDLLEKERISQASLREKLELENLFSKKLQQQKELKYQIKNELTIELTRLRKDL 859 Query: 326 KKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSP 385 +I+ E + QI+ + E+E + K++ SK I K K++ Sbjct: 860 SQIQ--EFVQHQIKMKSNEIELWV-------KSIQGKSKD----ILNKQNNQLQEKLQIV 906 Query: 386 WSQLSSETLNQDTDKKIN-KNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXG 444 +++S E Q D K + EI+ L+ + K L D +S+ + Sbjct: 907 ENEISRECEEQIQDYKHRFEQEISDLQQQKEREIKQLSDYVNKLSQANQDLINESKGYQE 966 Query: 445 K-DTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIE 503 + + L Q L QQ+ + + K EQ++Q + + + + Sbjct: 967 ELNELKNQYDLLQQQNQ---------NLQKSYDNAIKKSEQMEQTFDLRLSEYQQR---- 1013 Query: 504 KLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVR--LT 561 K +S ++ + E+D AN+ +I+ K+ ++ + QM K ++ + E VR + Sbjct: 1014 KEESGLKRKQMVERELDIANEEIIQWKNKYQNLIDQMNKNVEQMQSQREIEVETVRQKMN 1073 Query: 562 EELHHLSQKVAELEEEKGNLQLHLV-DYDSGRMIESDVYKKMIEMENL---AETRLKAIS 617 + L ++ L++ + L+ L D +++ + +K E L + ++K+++ Sbjct: 1074 FSIQQLESQIEMLQQNELELRDSLAKQNDKINLLQKIIQEKEEAFEGLRREKDQQIKSVT 1133 Query: 618 LLESQKFDLVQE-LHILQQKYDEV-EDKLADISQLQSDQVCSEIKSVHLEEQIDALSASK 675 +E + + L +E L ++ YDE+ ++ I+ ++ K L E+ L Sbjct: 1134 EVELE-YKLKEEGLRKQKKSYDEILREQEEKINHFVNEITILNSKINQLIEEKTILINKN 1192 Query: 676 KELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISEL 735 K+L L L + QL K+ +DK+ NK + + + + K ++E I +L Sbjct: 1193 KDLQF---QLDLKQSQLNQLAKEF-HDKQTKSNKEIEDLHKLLTQSFKNMNDNSENI-DL 1247 Query: 736 LAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSK 773 K+ +E++++ T+ D +Q + Y+E +S SK Sbjct: 1248 ARKL--DEETRLLTKKVKD--LQHINRYLEISKSPSSK 1281 >UniRef50_UPI0000F2D5B2 Cluster: PREDICTED: similar to centromere protein E; n=2; Mammalia|Rep: PREDICTED: similar to centromere protein E - Monodelphis domestica Length = 2638 Score = 139 bits (336), Expect = 7e-31 Identities = 235/1240 (18%), Positives = 536/1240 (43%), Gaps = 101/1240 (8%) Query: 147 LSNTIKEKDNALSVLQVK---MKIMETTILDLQEKINEKDQI---IEAKNKATTXXXXXX 200 L++T ++ + + LQ K M + +++ QEK+NE +QI +E+KN Sbjct: 1118 LADTEEKLNKKIQELQEKENQMLNVRKEVIEAQEKVNEMEQIRNQLESKNSTLERVEIEN 1177 Query: 201 XXXXXXXXXXXEDTK---QQMTKMQENFIAMEAEWKDEKQRLLKDIESK------DVRIS 251 E T Q++ + ++ +A++ E +D+ + +K++ +K ++RI+ Sbjct: 1178 LKLAQKLQASLEQTSSITQEINEFKKTQVALQLE-RDQLKENIKEVVTKGLETQEELRIA 1236 Query: 252 --SLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXL--AKQSIEPSCEEK 307 L++ + ++ + +S + +++++ E L K+ + EE Sbjct: 1237 QMGLKDHQETIDRLKECVSEKVAQVSKNQEAFEKTKAELQEKIQELQEKKEQVVNVREEN 1296 Query: 308 TEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGS 367 +E+EEK + + +L K+++ E +I N EL KL E+ V+ Sbjct: 1297 SEVEEK----VIEIEQLKKQLKTKECTLERIEMENLELAQKLQASLEETTCVAK------ 1346 Query: 368 PLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYV 427 R QL ET+ +D KI + E AK E + +D D+ Sbjct: 1347 ---ERDELTKIQEAFYIEMEQL-KETI-RDLRAKIQELE-AKQEQIFNVREEDNEDQ--- 1397 Query: 428 ISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHME--GPSLIHVGTNTEDVNEIAKVQEQL 485 EK K++++ ++ LE+ + + SL + E+ +E+ K++E L Sbjct: 1398 --EKMKEMEQLKEQLMSKESILERISLENLELAQKLQASLEETTSVAEERDELTKIKEAL 1455 Query: 486 ---KQELNDEIKDVNVKDL--IEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQM 540 + +L + I+D+ KDL E+L+ A+ + + + +D K I K + + Q+ Sbjct: 1456 HIERDQLKETIRDLRAKDLEIQEELRIAQMSLKEHQETVDKL-KECISEKEDIEKTSAQL 1514 Query: 541 QKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYK 600 Q+ I ++ + +++ + EE++ + + E+E+ K L + M ++ + Sbjct: 1515 QEKI---QELQTNQEQMFSVREEINKTQENIKEVEQLKEQLMSKESSLERIEMENLELAQ 1571 Query: 601 K----MIEMENLAETRLKAISLLES---QKFDLVQELHILQQKYDEVEDKLADISQLQSD 653 K + E+ ++A+ R + + E+ ++ L + + L+ K E+E K + ++ + Sbjct: 1572 KLQASLEEINSVAKERDELTKIQEAFYIERDQLKEAIRDLRAKIQELESKQEQMFNVREE 1631 Query: 654 QVCSEIKSVHLEEQIDALSASKKELALV-IENLKLDKEQLYGTIKDLEN--DKEDIMNKL 710 ++ K +E+ + L + + L + +ENL+L ++L ++++ + ++ D + K+ Sbjct: 1632 DNEAQEKMKEMEQLKEQLISKESTLERISLENLEL-AQKLQASLEETTSVAEERDELTKI 1690 Query: 711 QNYIQ-ENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIES 769 + + E L + + + A+ + E+ ++ ++S + Q +D K++E E++E Sbjct: 1691 KEALHIERDQLKETIRDLRAKDL-EIQEELRIAQKSLKEHQETVD-KLKECISEKEDVEK 1748 Query: 770 ELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAV 829 ++ + + +E + + + + D+L + EK+ + Q E + L Sbjct: 1749 TSAQLQEKDLETQEELRIAQKSLKEHQETVDKLKECISEKEDV-EKTRAQLQEKIQELES 1807 Query: 830 LMDHDRVVEKQLLEIEHENKEL-QKKNQILLEENQNLQISLSDMQ--QHYNALVEKANRT 886 V ++ E + + KE+ Q K Q++ +E +ISL +++ Q A +E+ Sbjct: 1808 KQKQMFNVREEDNEAQEKMKEMEQLKEQLISKEFTLERISLENLELAQKLQASLEETTSV 1867 Query: 887 DLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVL 946 E TK + L LK+ + + ++ ++E+ ++ E+ R K+ + Sbjct: 1868 AEERDELTKIKEALHIERDQLKKTIRDLRAKGLETQEELRIAQMGLKDHQETIDRLKECV 1927 Query: 947 NEK---YEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDY 1003 +EK KN E + +A+LQE ++ V + + N E+ +K ++ +Q + Sbjct: 1928 SEKVAQVSKNQEAFEKTKAELQEKIQELQEKKEQVVNVREENSEVEEKVIEIEQLKKQLK 1987 Query: 1004 TEQ-YINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEE 1062 T++ + I N L QK + + + + + + ++ Q + ++ Sbjct: 1988 TKECTLERIEMENLELAQKLQASLEETTCVTKERDELTKIQEAFYIEMEQLKETIRDLRA 2047 Query: 1063 EMQRVSKQLL--------DSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMII 1114 + Q+ K+L+ D KQH E ++E+ +I EL++ E + Sbjct: 2048 KNQQKPKELVKMEATARKDIKQHPIE---SLKEKCSKINELQKKYTMMENRCGFLSK--L 2102 Query: 1115 SSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTK 1174 S ++ + N + L E+ R + N +L T Sbjct: 2103 SVDLKKAFESQNELQVKVRASLYHTPQLTKAVEKILASNR--------RCNNDLHSSSTC 2154 Query: 1175 II-QLETLNTELTGHDVVNQEQINQLKSKL-EQLNTENDNLLSTVAELRSSISSAVDQRG 1232 I+ +LE + + G + +N+ + L + +N+ L+ T + S +++ G Sbjct: 2155 ILRKLEGVLKRVVGLRKEHHTTVNKFQMDLIREAERQNELLVKTQHLQQHSQGGSLESSG 2214 Query: 1233 FEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQV 1292 +++++ H+ Q D +T++++ ++ F +QLL++ + + T V Sbjct: 2215 YKLSQKMNLHVEQILKDVSETQNDVHNMIAEF----QQLLNAKKEIILFLDVCLNTHFDV 2270 Query: 1293 TSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKV 1332 L+ +Q++ + + N+ Y + I I SE ED+ + Sbjct: 2271 ECLKKVIQEENDRIVNVNNSYCNKIKAIINESSEFEDKSI 2310 Score = 126 bits (303), Expect = 7e-27 Identities = 251/1175 (21%), Positives = 517/1175 (44%), Gaps = 151/1175 (12%) Query: 215 KQQMTKMQENFIAMEAEWKDEK-QRLLKDIESK-DVRISSLEEANKLLEAARFEISLEHS 272 KQQ ++E E E + + Q L D E K + +I L+E + R E+ +E Sbjct: 1092 KQQEAVLKERRKTAEKEGELVRTQERLADTEEKLNKKIQELQEKENQMLNVRKEV-IEAQ 1150 Query: 273 KLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLE 332 + E+EQ + ++++ + + + +E+ S+ + E K L+ Sbjct: 1151 EKVNEMEQIRNQLESKNSTLERVEIENLKLAQKLQASLEQTSSIT-QEINEFKKTQVALQ 1209 Query: 333 HLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQ-LSS 391 Q+++ KE+ T G E++ ++ G K + T ++K S+ ++ Sbjct: 1210 LERDQLKENIKEV----VTKGLETQEELRIAQMGL-----KDHQETIDRLKECVSEKVAQ 1260 Query: 392 ETLNQDTDKKINKNEIAKLEMVIQSLNKDLV---DKEYVISEKDTXXXXXXXXXXGKDTL 448 + NQ+ +K K E+ + +Q + +V ++ + EK K+ Sbjct: 1261 VSKNQEAFEK-TKAELQEKIQELQEKKEQVVNVREENSEVEEKVIEIEQLKKQLKTKECT 1319 Query: 449 IAQLQLEHQQHMEG--PSLIHVGTNTEDVNEIAKVQEQL---KQELNDEIKDVNVKDLIE 503 + ++++E+ + + SL ++ +E+ K+QE ++L + I+D+ K I+ Sbjct: 1320 LERIEMENLELAQKLQASLEETTCVAKERDELTKIQEAFYIEMEQLKETIRDLRAK--IQ 1377 Query: 504 KLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEE 563 +L++ +EQI + +E N++ K+K +LK + M K ++S N E L ++ Sbjct: 1378 ELEAKQEQIFNVREE---DNEDQEKMKEMEQLKEQLMSKE-SILERISLENLE---LAQK 1430 Query: 564 LHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQK 623 L ++ + EE+ L I+ ++ IE + L ET I L ++ Sbjct: 1431 LQASLEETTSVAEERDELT----------KIKEALH---IERDQLKET----IRDLRAKD 1473 Query: 624 FDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIE 683 ++ +EL I Q E ++ + + + S++ E S L+E+I L +++++ V E Sbjct: 1474 LEIQEELRIAQMSLKEHQETVDKLKECISEKEDIEKTSAQLQEKIQELQTNQEQMFSVRE 1533 Query: 684 NLKLDKEQLYGTIKDLENDKEDIMNK---LQNYIQENMDLTDKLEKMSAEKISELLAKIN 740 + +E IK++E KE +M+K L+ EN++L KL+ S E+I+ + AK Sbjct: 1534 EINKTQEN----IKEVEQLKEQLMSKESSLERIEMENLELAQKLQA-SLEEINSV-AK-E 1586 Query: 741 HEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLER--K 798 +E +KIQ F I ERD E I +K + + E+ V E+ + E+ + Sbjct: 1587 RDELTKIQEAFYI-----ERDQLKEAIRDLRAKIQELESKQEQMFNVREEDNEAQEKMKE 1641 Query: 799 ADQLGSYLQEKQKAYSEYTIQEDELVNRL--------AVLMDHDRVVE-KQLLEIEHEN- 848 +QL L K+ +++ EL +L +V + D + + K+ L IE + Sbjct: 1642 MEQLKEQLISKESTLERISLENLELAQKLQASLEETTSVAEERDELTKIKEALHIERDQL 1701 Query: 849 ----KELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLE 904 ++L+ K+ + EE + Q SL + Q+ + L E + + + E T Q Q +DLE Sbjct: 1702 KETIRDLRAKDLEIQEELRIAQKSLKEHQETVDKLKECISEKE--DVEKTSAQLQEKDLE 1759 Query: 905 SNLK-RITH----EHQTLI------VQKKKEIEDLEIEFNTQI-ESAIRDKKVLNEKYEK 952 + + RI EHQ + + +K+++E + +I E + K++ N + E Sbjct: 1760 TQEELRIAQKSLKEHQETVDKLKECISEKEDVEKTRAQLQEKIQELESKQKQMFNVREED 1819 Query: 953 N-----IEYVTQLEAQLQEYKNNIENLNM-NVEELNKMNLELIDK-HVQKQQTQSPDYTE 1005 N ++ + QL+ QL + +E +++ N+E K+ L + V +++ + E Sbjct: 1820 NEAQEKMKEMEQLKEQLISKEFTLERISLENLELAQKLQASLEETTSVAEERDELTKIKE 1879 Query: 1006 -------QYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFT---- 1054 Q I L A + EE+ + + Q + + K+AQ + Sbjct: 1880 ALHIERDQLKKTIRDLRAKGLETQEELRIAQMGLKDHQETIDRLKECVSEKVAQVSKNQE 1939 Query: 1055 ----TKLENME--EEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPK 1108 TK E E +E+Q +Q+++ ++ N E++ V E + K+LK + T E + Sbjct: 1940 AFEKTKAELQEKIQELQEKKEQVVNVREENSEVEEKVIEIEQLKKQLKTKECTLER--IE 1997 Query: 1109 TEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTEL 1168 E + ++ ++ ++ V K+Q E F E L+E L + Sbjct: 1998 MENLELAQKLQASLEETTCV------TKERDELTKIQ--EAFYIEMEQLKETIRDLRAKN 2049 Query: 1169 QECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAV 1228 Q+ +++++E T + Q I LK K ++N EL+ + Sbjct: 2050 QQKPKELVKMEA-----TARKDIKQHPIESLKEKCSKIN-----------ELQKKYTMME 2093 Query: 1229 DQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFES-KYEQLLDSVQSSTQEETNKIV 1287 ++ GF L K + ++A + E +++V+ S + + + + ++ + +S + N + Sbjct: 2094 NRCGF----LSKLSVDLKKAFESQNELQVKVRASLYHTPQLTKAVEKILASNRRCNNDLH 2149 Query: 1288 TMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEI 1322 + T + KL+ + + L++++ +N+ ++ Sbjct: 2150 SSS--TCILRKLEGVLKRVVGLRKEHHTTVNKFQM 2182 Score = 120 bits (290), Expect = 3e-25 Identities = 277/1385 (20%), Positives = 596/1385 (43%), Gaps = 145/1385 (10%) Query: 319 ANMTELTKKIELLEHLNCQIRQT-NKELE-NKLATMGTESKAVSSPSKKGSPLIS----- 371 AN L E L+ N +I Q N++LE + T+ E +++ + +++ Sbjct: 504 ANFDNLVLDYEQLQIKNAEIEQKLNEKLELEEFVTL--EMQSIKEQEVRNHEILNIMKHE 561 Query: 372 RKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEK 431 K +++ ++ S SQL E Q +K + I +E+ + + + + +E ++ Sbjct: 562 DKDDQDSENEQNSK-SQLLKEKEEQIKEKFLELQLIKNIELDLY-YDGEKIYEELKHLKQ 619 Query: 432 DTXXXXXXXXXXGKDTLIAQLQ-LEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELN 490 K+T + + LE ++ M+ L E N + Q QL QE Sbjct: 620 SLCDTETIALDAQKETAFLKCENLELKEKMK--ELSSQCKQLEKDNHL--YQSQL-QERR 674 Query: 491 DEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKV 550 D K DL ++L+SA +IT+L I+ + + + K+K +QK +D K Sbjct: 675 DSSKRRQA-DLEKELQSAFSEITRLTSIIEGKYPKDVLLTVELERKVKDLQKDLDKAIKE 733 Query: 551 SDSNKEIVRLTEELHHLSQKVAELEEEK--GNLQLHLVDYDSGRMIESDVYK--KMIEME 606 + + ++ + EL L ++ L++E+ + +L+L+ + ++ +YK ++ E+ Sbjct: 734 NATLQKEINTLSELKSLPTELEILKKERLEKSEELNLIIAEKDKLRAEIMYKDNRLQELL 793 Query: 607 NLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLE- 665 + E + ++ ++ QE +Q + E E + + + +++ +I++V +E Sbjct: 794 DEIEKSKEELAAAQATHQTTTQEFQDFKQYHGEFEQNYFTVLE-EIEKMKHQIRTVSVEA 852 Query: 666 EQI-----DALSASKKE----LALVIENL-----KLDKEQLYGTIKDLENDKEDIMNKLQ 711 +I D +S KE L V E L KL+ E+L G L +E+ L Sbjct: 853 HEIALDFDDLVSEPTKEVREKLLEVREQLCKAQQKLE-ERLSGRRSSLRTSEEE-TQFLP 910 Query: 712 NYIQENMDLTD-KLEKMSAEKISELLAKINHE---EQSKIQTQFGIDAKIQER-DLYIEN 766 + E++ ++ EK + E+ +L + E ++ + + D QE Y E+ Sbjct: 911 KSLHEHLQVSSGTCEKDAPEQFPKLPFQTKEEQPRQELHAASHWSTDKGTQEELRNYSES 970 Query: 767 IESELSKYKSRI-CRLEESIAV---MEDRRYSLERKADQL--GSYLQEKQKAYSEYTIQE 820 + + +K S + RL E V E+ L+ K +L G L+ + ++ Sbjct: 971 HKCQDTKDSSSMPTRLSEESGVKGIQEEALDELQGKTVKLNEGQNLESPRNLVPLPDYEK 1030 Query: 821 D-ELV---NRLAVLMDHDRVVEKQLLEIEHENK----ELQKKNQILLEENQNLQISLSDM 872 D EL+ +++ L+ +++ L + E +L++ + +E + L+ + + Sbjct: 1031 DNELLQQQRKISSLIQEKNQLQQMLECVTAEKNQLKTDLEENIGMSIENQEELRNIGAAL 1090 Query: 873 QQHYNALVEKANRTDLAESESTKYQTQLRDLESNL-KRI--THEHQTLIVQKKKEIEDLE 929 ++ A++++ +T E E + Q +L D E L K+I E + ++ +KE+ + + Sbjct: 1091 KKQQEAVLKERRKTAEKEGELVRTQERLADTEEKLNKKIQELQEKENQMLNVRKEVIEAQ 1150 Query: 930 IEFN--TQIESAIRDKKVLNEKYE-KNIEYVTQLEAQLQEYKNNIENLN--MNVEELNKM 984 + N QI + + K E+ E +N++ +L+A L++ + + +N + ++ Sbjct: 1151 EKVNEMEQIRNQLESKNSTLERVEIENLKLAQKLQASLEQTSSITQEINEFKKTQVALQL 1210 Query: 985 NLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVS 1044 + + +++++ T+ + E E+ LK E I L + ++ ++ VS Sbjct: 1211 ERDQLKENIKEVVTKGLETQE----ELRIAQMGLKDHQETIDRLKECVSEK----VAQVS 1262 Query: 1045 DYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFE- 1103 + + +L+ +E+Q +Q+++ ++ N E++ V E + K+LK + T E Sbjct: 1263 KNQEAFEKTKAELQEKIQELQEKKEQVVNVREENSEVEEKVIEIEQLKKQLKTKECTLER 1322 Query: 1104 MNIPKTE-GMIISSTIEPMSDDANNVDXXXXXXXXXXXXLK-----VQEEEEFIQERSVL 1157 + + E + +++E + A D ++ +++ IQE Sbjct: 1323 IEMENLELAQKLQASLEETTCVAKERDELTKIQEAFYIEMEQLKETIRDLRAKIQELEAK 1382 Query: 1158 QEQSAKLNTELQECYTKIIQLETLNTELTGHDVV-------NQEQINQLKSKLEQ----- 1205 QEQ + E E K+ ++E L +L + + N E +L++ LE+ Sbjct: 1383 QEQIFNVREEDNEDQEKMKEMEQLKEQLMSKESILERISLENLELAQKLQASLEETTSVA 1442 Query: 1206 ------------LNTENDNLLSTVAELRSS---------ISSAVDQRGFEIAELWKQHLA 1244 L+ E D L T+ +LR+ I+ + E + K+ ++ Sbjct: 1443 EERDELTKIKEALHIERDQLKETIRDLRAKDLEIQEELRIAQMSLKEHQETVDKLKECIS 1502 Query: 1245 QREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKI-VTMEQVTSLQNKLQDKE 1303 ++E D +KT +L+ ++ ++ EQ+ S +EE NK +++V L+ +L KE Sbjct: 1503 EKE-DIEKTSAQLQEKIQELQTNQEQMF-----SVREEINKTQENIKEVEQLKEQLMSKE 1556 Query: 1304 EHLRNLQEKYADVINQIEILRSEI------EDEKVAFXXXXXXXXXXXXXXXXDLRTENQ 1357 L ++ + ++ +++ EI DE DLR + Q Sbjct: 1557 SSLERIEMENLELAQKLQASLEEINSVAKERDELTKIQEAFYIERDQLKEAIRDLRAKIQ 1616 Query: 1358 SYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIY 1417 + QEQ + N+ EE+ + ++ + + E LE LEL ++ Sbjct: 1617 ELESKQEQ-MFNVREEDNEAQEKMKEMEQLKEQLISKESTLERISLE---NLEL--AQKL 1670 Query: 1418 QKTHEYTITLTQRNDEFENVRQQL-VEYEKRIEDLTYEKESELAI---LRLKMHENANHY 1473 Q + E T ++ + DE +++ L +E ++ E + + +L I LR+ H Sbjct: 1671 QASLEETTSVAEERDELTKIKEALHIERDQLKETIRDLRAKDLEIQEELRIAQKSLKEHQ 1730 Query: 1474 ETMQKESE-IERVKLIEELNVKITE-SVSLNKQVAELNKAL---EEEVAKTNEMQTALEN 1528 ET+ K E I + +E+ + ++ E + +++ K+L +E V K E + E+ Sbjct: 1731 ETVDKLKECISEKEDVEKTSAQLQEKDLETQEELRIAQKSLKEHQETVDKLKECISEKED 1790 Query: 1529 QEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKEL-LDAVPRA 1587 E L ++I L++ + +++ + A + + ++ + ++KE L+ + Sbjct: 1791 VEKTRAQLQEKIQELESK-QKQMFNVREEDNEAQEKMKEMEQLKEQLISKEFTLERISLE 1849 Query: 1588 ELDLA 1592 L+LA Sbjct: 1850 NLELA 1854 Score = 113 bits (272), Expect = 4e-23 Identities = 236/1237 (19%), Positives = 512/1237 (41%), Gaps = 107/1237 (8%) Query: 49 ERQIKFERAQKCL-ENAALVSKRIKEHRKATAELLGR-PFVPGISESLANTLKQKEILME 106 + Q +R ++C+ E A VSK + K AEL + + E + N ++ + E Sbjct: 1242 DHQETIDRLKECVSEKVAQVSKNQEAFEKTKAELQEKIQELQEKKEQVVNVREENSEVEE 1301 Query: 107 KIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNALSVLQ---V 163 K+ + ++L K+ T Q + + KE+D + + + Sbjct: 1302 KVIEIEQLKKQLKTKECTLERIEMENLELAQKLQ-ASLEETTCVAKERDELTKIQEAFYI 1360 Query: 164 KMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQE 223 +M+ ++ TI DL+ KI E +EAK + E K+Q+ + Sbjct: 1361 EMEQLKETIRDLRAKIQE----LEAKQEQI-FNVREEDNEDQEKMKEMEQLKEQLMSKES 1415 Query: 224 NFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXX 283 + E + Q+L +E +E K+ EA E + + ++L Sbjct: 1416 ILERISLENLELAQKLQASLEETTSVAEERDELTKIKEALHIERD-QLKETIRDLRAKDL 1474 Query: 284 XXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNK 343 K+ E + K I EK +E + +L +KI+ L+ Q+ + Sbjct: 1475 EIQEELRIAQMSLKEHQETVDKLKECISEKEDIEKTS-AQLQEKIQELQTNQEQMFSVRE 1533 Query: 344 ELENKLATMG-TESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKI 402 E+ + E SK+ S A K+++ +++S +D KI Sbjct: 1534 EINKTQENIKEVEQLKEQLMSKESSLERIEMENLELAQKLQASLEEINSVAKERDELTKI 1593 Query: 403 N----------KNEIAKLEMVIQSLNK------DLVDKEYVISEKDTXXXXXXXXXXGKD 446 K I L IQ L ++ +++ EK K+ Sbjct: 1594 QEAFYIERDQLKEAIRDLRAKIQELESKQEQMFNVREEDNEAQEKMKEMEQLKEQLISKE 1653 Query: 447 TLIAQLQLEHQQHMEG--PSLIHVGTNTEDVNEIAKVQEQL---KQELNDEIKDVNVKDL 501 + + ++ LE+ + + SL + E+ +E+ K++E L + +L + I+D+ KDL Sbjct: 1654 STLERISLENLELAQKLQASLEETTSVAEERDELTKIKEALHIERDQLKETIRDLRAKDL 1713 Query: 502 I--EKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVR 559 E+L+ A++ + + + +D + + + + K + +K ++ ++ + K + Sbjct: 1714 EIQEELRIAQKSLKEHQETVDKLKECISEKEDVEKTSAQLQEKDLETQEELRIAQKSLKE 1773 Query: 560 LTEELHHLSQKVAELEE-EKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISL 618 E + L + ++E E+ EK QL + + +ES K +M N+ E Sbjct: 1774 HQETVDKLKECISEKEDVEKTRAQLQ----EKIQELES----KQKQMFNVREE------- 1818 Query: 619 LESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKEL 678 +++ + ++E+ L+++ E L IS L++ ++ ++++ LEE +++ + EL Sbjct: 1819 -DNEAQEKMKEMEQLKEQLISKEFTLERIS-LENLELAQKLQA-SLEETT-SVAEERDEL 1874 Query: 679 ALVIENLKLDKEQLYGTIKDLENDKEDIMNKL---QNYIQENMDLTDKLEKMSAEKISEL 735 + E L ++++QL TI+DL + +L Q ++++ + D+L++ +EK++++ Sbjct: 1875 TKIKEALHIERDQLKKTIRDLRAKGLETQEELRIAQMGLKDHQETIDRLKECVSEKVAQV 1934 Query: 736 LAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSL 795 E++K + Q I ++QE+ + N+ E S+ + ++ +E+ ++ + +L Sbjct: 1935 SKNQEAFEKTKAELQEKIQ-ELQEKKEQVVNVREENSEVEEKVIEIEQLKKQLKTKECTL 1993 Query: 796 ERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKN 855 ER + Q+ Q + E T E + L + + + +QL E ++L+ KN Sbjct: 1994 ERIEMENLELAQKLQASLEETTCVTKER-DELTKIQEAFYIEMEQLKETI---RDLRAKN 2049 Query: 856 QILLEENQNLQISL-SDMQQH-YNALVEKANRTDLAESESTKYQTQ---LRDLESNLKRI 910 Q +E ++ + D++QH +L EK ++ + + + T + + L L +LK+ Sbjct: 2050 QQKPKELVKMEATARKDIKQHPIESLKEKCSKINELQKKYTMMENRCGFLSKLSVDLKKA 2109 Query: 911 THEHQTLIVQKKKEIEDLEIEFNTQIESAIR-DKKVLNEKYEKNIEYVTQLEAQLQ---- 965 L V+ + + + +E + +++ N+ + + + +LE L+ Sbjct: 2110 FESQNELQVKVRASLYHTP-QLTKAVEKILASNRRCNNDLHSSSTCILRKLEGVLKRVVG 2168 Query: 966 ---EYKNNIENLNMN-VEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQ- 1020 E+ + M+ + E + N L+ +Q +Q K+N ++Q Sbjct: 2169 LRKEHHTTVNKFQMDLIREAERQNELLVKTQHLQQHSQGGSLESSGYKLSQKMNLHVEQI 2228 Query: 1021 -KD--------EEIIALNQKINNAQ---VSYMSM-------VSDYESKLAQFTTKLENME 1061 KD +IA Q++ NA+ + ++ + V + + + ++ N+ Sbjct: 2229 LKDVSETQNDVHNMIAEFQQLLNAKKEIILFLDVCLNTHFDVECLKKVIQEENDRIVNVN 2288 Query: 1062 EEMQRVSKQLLDSKQHNEELQIL-VREQDDQIKELKET--KLTFEMNIPKTEGMIISSTI 1118 K +++ E+ I+ +E + +++++KE +L ++ +T ++ + Sbjct: 2289 NSYCNKIKAIINESSEFEDKSIIECKEWEHELRQMKEENEELVKKLQTTQTPPTALND-L 2347 Query: 1119 EPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQL 1178 + +S D K F +E L+ + KLN E K + Sbjct: 2348 DALSGGEKKHDLKLRHTGRTTKDAKATLGAVFSKEIDDLKMKLVKLNMEKMNESKKFEKE 2407 Query: 1179 ETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLS 1215 T + H N+E I+QLK +L + ND +S Sbjct: 2408 IASKTAIIEH---NEEIISQLKERLRRAQQCNDTSMS 2441 Score = 60.1 bits (139), Expect = 5e-07 Identities = 118/606 (19%), Positives = 248/606 (40%), Gaps = 48/606 (7%) Query: 743 EQSKIQTQFGIDAKIQERDLYIENI---ESELSKYKSRICRLEESIAVMEDRRYSLERKA 799 E++ QF AK + ++ + E+ L +Y+ I L++ + + + Sbjct: 314 EETLSTLQFASTAKYMKNTPHVNEVLDDEALLKRYRKEIIDLKKQLEEVSSETRVQAMEK 373 Query: 800 DQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILL 859 DQL L+EK +Q D++ N +L+ + +Q L+ + + + ++ Sbjct: 374 DQLAQLLEEKDLLQK---VQNDKIQNLTQMLVTSSSITIQQDLKAKRKRRVTWCPGKM-- 428 Query: 860 EENQNLQISLSDMQQHYNALVEKANRTDL-AESESTKYQTQLRDLESNLKRITHEHQTLI 918 N+ I D LV K+ + L +++ + D+ SN E + Sbjct: 429 --NKMKDIGYMDDFDITKTLVAKSVKPALPIIADTDESMCSEFDIFSNTLETISEMEWNP 486 Query: 919 VQKKKEIEDLEIEFNT---QIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLN 975 K + E+++ E N+ ++ + D + L K IE + +L+E+ +E + Sbjct: 487 ATKLNQ-ENVQSELNSLRANFDNLVLDYEQLQIK-NAEIEQKLNEKLELEEFV-TLEMQS 543 Query: 976 MNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEI---IALNQKI 1032 + +E+ + I KH K S NE N + LLK+K+E+I Q I Sbjct: 544 IKEQEVRNHEILNIMKHEDKDDQDSE-------NEQNSKSQLLKEKEEQIKEKFLELQLI 596 Query: 1033 NNAQVS-YMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQ 1091 N ++ Y YE +L L + E K+ K N EL+ ++E Q Sbjct: 597 KNIELDLYYDGEKIYE-ELKHLKQSLCDTETIALDAQKETAFLKCENLELKEKMKELSSQ 655 Query: 1092 IKELK------ETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQ 1145 K+L+ +++L + K + ++ + + L V+ Sbjct: 656 CKQLEKDNHLYQSQLQERRDSSKRRQADLEKELQSAFSEITRLTSIIEGKYPKDVLLTVE 715 Query: 1146 EEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQ 1205 E + +++ +++ K N LQ+ + +L++L TEL +++ +E++ + +L Sbjct: 716 LERK-VKDLQKDLDKAIKENATLQKEINTLSELKSLPTEL---EILKKERLEK-SEELNL 770 Query: 1206 LNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFE 1265 + E D L + + + + +D+ E K+ LA +A Q T E + + Sbjct: 771 IIAEKDKLRAEIMYKDNRLQELLDE-----IEKSKEELAAAQATHQTTTQEFQ-DFKQYH 824 Query: 1266 SKYEQLLDSVQSSTQEETNKIVTME-QVTSLQNKLQD-KEEHLRNLQEKYADVINQIEIL 1323 ++EQ +V ++ ++I T+ + + D E + ++EK +V Q+ Sbjct: 825 GEFEQNYFTVLEEIEKMKHQIRTVSVEAHEIALDFDDLVSEPTKEVREKLLEVREQLCKA 884 Query: 1324 RSEIED 1329 + ++E+ Sbjct: 885 QQKLEE 890 Score = 54.0 bits (124), Expect = 3e-05 Identities = 103/553 (18%), Positives = 240/553 (43%), Gaps = 63/553 (11%) Query: 813 YSEYTIQEDELVNRLAVLMDHDRVV---EKQLLEIEHENK-ELQKKNQI--LLEENQNLQ 866 Y + T +E+++ A+L + + + +KQL E+ E + + +K+Q+ LLEE LQ Sbjct: 328 YMKNTPHVNEVLDDEALLKRYRKEIIDLKKQLEEVSSETRVQAMEKDQLAQLLEEKDLLQ 387 Query: 867 ISLSDMQQHYNALVEKANRTDLAESESTKYQTQLR---DLESNLKRITHEH-----QTLI 918 +D Q+ ++ ++ + + K + ++ + +K I + +TL+ Sbjct: 388 KVQNDKIQNLTQMLVTSSSITIQQDLKAKRKRRVTWCPGKMNKMKDIGYMDDFDITKTLV 447 Query: 919 VQKKKE----IEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQ--LEAQLQEYKNNIE 972 + K I D + ++ + + ++E + Q ++++L + N + Sbjct: 448 AKSVKPALPIIADTDESMCSEFDIFSNTLETISEMEWNPATKLNQENVQSELNSLRANFD 507 Query: 973 NLNMNVEELNKMNLELIDKHVQKQQTQS------PDYTEQYINEINKLNALLKQKDEEII 1026 NL ++ E+L N E+ K +K + + EQ + LN ++K +D++ Sbjct: 508 NLVLDYEQLQIKNAEIEQKLNEKLELEEFVTLEMQSIKEQEVRNHEILN-IMKHEDKD-- 564 Query: 1027 ALNQKINNAQVSYMSMVSDYESKLAQFTTKLE---NMEEEMQRVSKQLLDSKQHNEELQI 1083 +Q N Q S ++ + E ++ + +L+ N+E ++ +++ + +H + Q Sbjct: 565 --DQDSENEQNSKSQLLKEKEEQIKEKFLELQLIKNIELDLYYDGEKIYEELKHLK--QS 620 Query: 1084 LVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLK 1143 L + + KET K E + + ++ +S ++ Sbjct: 621 LCDTETIALDAQKETAFL------KCENLELKEKMKELSSQCKQLEKDNHLY-------- 666 Query: 1144 VQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKL 1203 + + + R + + A L ELQ +++I +L ++ DV+ +L+ K+ Sbjct: 667 ---QSQLQERRDSSKRRQADLEKELQSAFSEITRLTSIIEGKYPKDVL---LTVELERKV 720 Query: 1204 EQLNTENDNLLSTVAELRSSISSAVDQRGF--EIAELWKQHLAQ-READFQKTEHE-LRV 1259 + L + D + A L+ I++ + + E+ L K+ L + E + E + LR Sbjct: 721 KDLQKDLDKAIKENATLQKEINTLSELKSLPTELEILKKERLEKSEELNLIIAEKDKLRA 780 Query: 1260 QLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQ 1319 ++ +++ ++LLD ++ S +E T + T + QD +++ ++ Y V+ + Sbjct: 781 EIMYKDNRLQELLDEIEKSKEELAAAQATHQTTT---QEFQDFKQYHGEFEQNYFTVLEE 837 Query: 1320 IEILRSEIEDEKV 1332 IE ++ +I V Sbjct: 838 IEKMKHQIRTVSV 850 >UniRef50_UPI00004995B4 Cluster: myosin heavy chain; n=1; Entamoeba histolytica HM-1:IMSS|Rep: myosin heavy chain - Entamoeba histolytica HM-1:IMSS Length = 1312 Score = 139 bits (336), Expect = 7e-31 Identities = 256/1274 (20%), Positives = 517/1274 (40%), Gaps = 123/1274 (9%) Query: 396 QDTDKKINKNEIAKLEMVIQSLNKDLVDKE--------YVISEKDTXXXXXXXXXXGKDT 447 Q+ + K+ KNE+ E VI++ K+L + E ++ EK+ KD Sbjct: 62 QNENAKL-KNELQTKEDVIKNYQKELTEVEEKNKGVDDRILEEKEKRKSAELELENKKDD 120 Query: 448 LI-AQLQLEH-QQHMEG------PSLIHVGTNTEDVNE---IAKVQEQLKQELNDEIKDV 496 ++ Q + + +Q++ G + T T+ N+ KV ++ K++L E+ DV Sbjct: 121 ILELQAMVSNLKQNLAGLQQELKNKEEEIITETDKSNKALAAQKVYQEQKEKLESELADV 180 Query: 497 NVK------DLIEKLKSAE------EQITQ-----------LNDEIDAANKNMIKVKSNH 533 +K +L+ A+ E ITQ + +ID+ N + +V+ + Sbjct: 181 KIKLDTTQQELVATQARADGNEKEIEDITQEQNGWIRQAKEASKQIDSLNTELEEVEKDL 240 Query: 534 KLKLKQMQKTIDNFSK----VSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYD 589 ++K+ T + K + SN +I +L E+ L + AE +E K +V Sbjct: 241 DDEIKRHTATKADLEKTKNDLESSNNQINKLKEQ---LEKTKAEKDENKNVADQEVVTRK 297 Query: 590 SGRMIESDVYKKMIEMENLAETRLKAISLLE-------SQKFDLVQE-------LHILQ- 634 + SD+ KK+ + ET ++ L+ +K DL +E L +LQ Sbjct: 298 AVERKVSDLEKKVEGYKTDYETSQNLVNDLQVKLRAVTKEKEDLEKEYSSGNNILEVLQQ 357 Query: 635 --QKYDEVEDKLADISQLQSDQVCSEIKSV-HLEEQIDALSASKKELALVIENLKLDKEQ 691 QK DE KL D Q+ + ++ + LE AL+ EL L ++ K + Sbjct: 358 SKQKGDEEIIKLHDDLAEQAKKTTDAMRDIKQLEYDKVALNGEITELNLELDKQKQLVTK 417 Query: 692 LYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELL--AKINHEEQSKIQT 749 L +K L++DKE +++ EN LT+++ EL+ K+ E Q+ T Sbjct: 418 LQQEVKQLQDDKELNEQDIRDAGFENKKLTNQINDAKEAMDKELMKEEKLKQEIQALKDT 477 Query: 750 QFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEK 809 D + + + I N E + + ++ L E++ + + RK +Q+ + L+EK Sbjct: 478 IAKNDEEHDKLESDINNNEKTIKQLQNANKVLTENLENCTRDKEAALRKKEQVETDLKEK 537 Query: 810 QKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISL 869 + Y ++ EL ++L L + + + + I + K + LL++ Q L Sbjct: 538 SEEYDALNEKQRELNSQLVTLQKENAGLNETVGTISPD----LKNTKALLKQTQK---EL 590 Query: 870 SDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLE 929 D + L + E + + +LE K++ E + + KE E+L Sbjct: 591 KDAKDKIEGLTLDNEDLKKKQKEILEGHVSMEELEDYEKQLQREVAKIKQKSDKEAEELL 650 Query: 930 IEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELI 989 + + + ++N+ Y++N++ +TQ ++++ KN E + V++ K E I Sbjct: 651 DALDASDKKNEKLNNIINQ-YKENLDKLTQEHEEMEKAKNTAEKRVIIVQQDVKDKEETI 709 Query: 990 DKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESK 1049 K ++K + D I L + + + + ++ +N A SY + D Sbjct: 710 AK-LEKDKNTLKD-------RITDLESRIDGLEGGNVDVSVVVNAATESYKKQIDDLNKT 761 Query: 1050 LAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKT 1109 + + +++ +E++ + ++D K E + V + D++ + + + + + Sbjct: 762 IQDAKDQEKDLRDEIKDLRLDIVDLKGELESKEQEVNKAGDKLVLIDDENQSLKQTVND- 820 Query: 1110 EGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQE---RSVLQEQSAKLNT 1166 + I+ D+ N + + + EE+ QE LQ++ +NT Sbjct: 821 ----LKLKIKQSGDEKNELTMKIKYMELQMSAPQKEIEEKLNQEVMKNQDLQDEITSINT 876 Query: 1167 ELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSS--- 1223 +L E K E E+ N L++ ++ + L + VA+L + Sbjct: 877 QLAEAVEKRKASEAALEEMKEQMDGKIRNSNDLEATYQECFNKKTELENKVADLENQLEI 936 Query: 1224 ISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEET 1283 I +++++ +IA+L Q L+ D + ++ Q LD Q ++ Sbjct: 937 IKDSIEEKDDKIADLQSQ-LSSNSNDAVANDKLGDAMQLKIDTINRQYLDLKSKYDQLKS 995 Query: 1284 NKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXX 1343 + ++ + + ++ +L +E + ++ Y +IE L+ ++ K Sbjct: 996 DNLMVLSEKEDIEEELSSVKEEMTKMEGDYRKKAAEIEKLKHDVNFTK----QVTGDDAN 1051 Query: 1344 XXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVL 1403 D + Y + E S + +N QL+K ++ E ++ Sbjct: 1052 DLEKLQEDYDQLQEDYDDLMEDSDA-LTAKNQQLEKRVTELTDEVEISQDKIKALEKQLR 1110 Query: 1404 ELTHQLELKDSEIYQKTHEYTITLTQRND----EFENVRQQLVEYEKRIEDL---TYEKE 1456 + ++LE + +Y + + ND E + R ++ E E+ ++ L E++ Sbjct: 1111 KQNNELEDHADDAENADDDY-VRMKADNDKIRKERDEYRNKITEMEENMDQLKKTITEQD 1169 Query: 1457 SELAILRLKMHENANHYETMQKESEIERVKLIEELNVKI----TESVSLNKQVAELNKAL 1512 ++ LR E A + K+ E E K EEL K T+ KQ EL + + Sbjct: 1170 IKITELRGGNGEEALKIKAQIKQIEEENDKEKEELLAKAQQFKTKMNKFKKQAQELAEKV 1229 Query: 1513 EE-----EVAKTNEMQTALENQEIEIVTLNDEITNLQNMV---RASSSKIQKHVSFASDT 1564 E+ E AK + + + +I L DEI ++ + + SS++Q+ V+ Sbjct: 1230 EDLEGQLEKAKGSAAAAGASDLKSKIKDLQDEIEDVNQKLSSEKEKSSRLQRKVTSLESD 1289 Query: 1565 KQGRDEQLDNTMNK 1578 Q +DEQ+ K Sbjct: 1290 SQDKDEQIAKLKKK 1303 Score = 126 bits (304), Expect = 5e-27 Identities = 244/1230 (19%), Positives = 518/1230 (42%), Gaps = 113/1230 (9%) Query: 153 EKDNALSVLQVKMKIMETTILDLQEKI-NEKDQIIEAKNKATTXXXXXXXXXXXXXXXXX 211 +KD+ L LQ + ++ + LQ+++ N++++II +K+ Sbjct: 117 KKDDILE-LQAMVSNLKQNLAGLQQELKNKEEEIITETDKSNKALAAQKVYQEQKEKLES 175 Query: 212 E--DTKQQMTKMQENFIAMEAEWKDEKQRLLKDI-ESKDVRISSLEEANKLLEAARFEIS 268 E D K ++ Q+ +A +A D ++ ++DI + ++ I +EA+K +++ E+ Sbjct: 176 ELADVKIKLDTTQQELVATQAR-ADGNEKEIEDITQEQNGWIRQAKEASKQIDSLNTELE 234 Query: 269 LEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKI 328 L E+++ L + + + + K ++E+ + + N +++ Sbjct: 235 EVEKDLDDEIKRHTATKADLEKTKNDLESSNNQIN-KLKEQLEKTKAEKDENKNVADQEV 293 Query: 329 ELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQ 388 + + ++ K++E T V+ K + K + + Sbjct: 294 VTRKAVERKVSDLEKKVEGYKTDYETSQNLVNDLQVKLRAVTKEKEDLEKEYSSGNNILE 353 Query: 389 LSSETLNQDTDKKINK--NEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKD 446 + ++ Q D++I K +++A+ +D+ EY + + Sbjct: 354 VLQQS-KQKGDEEIIKLHDDLAEQAKKTTDAMRDIKQLEYDKVALNGEITELNLELDKQK 412 Query: 447 TLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLK 506 L+ +LQ E +Q + L N +D+ + ++L ++ND K+ K+L+++ K Sbjct: 413 QLVTKLQQEVKQLQDDKEL-----NEQDIRDAGFENKKLTNQINDA-KEAMDKELMKEEK 466 Query: 507 SAEEQITQLNDEIDAANKNMIKVKS---NHKLKLKQMQKT----IDNFSKVSDSNKEIVR 559 +E I L D I ++ K++S N++ +KQ+Q +N + + +R Sbjct: 467 LKQE-IQALKDTIAKNDEEHDKLESDINNNEKTIKQLQNANKVLTENLENCTRDKEAALR 525 Query: 560 LTEELH-HLSQKVAE---LEEEKGNLQLHLVDYDSGRM-IESDVYKKMIEMENLAETRLK 614 E++ L +K E L E++ L LV + V +++N + Sbjct: 526 KKEQVETDLKEKSEEYDALNEKQRELNSQLVTLQKENAGLNETVGTISPDLKNTKALLKQ 585 Query: 615 AISLLESQKFDLVQELHI----LQQKYDEVEDKLADISQLQS--DQVCSEIKSV------ 662 L+ K D ++ L + L++K E+ + + +L+ Q+ E+ + Sbjct: 586 TQKELKDAK-DKIEGLTLDNEDLKKKQKEILEGHVSMEELEDYEKQLQREVAKIKQKSDK 644 Query: 663 HLEEQIDALSASKKE---LALVIENLK--LDK-EQLYGTIKDLENDKEDIMNKLQNYIQE 716 EE +DAL AS K+ L +I K LDK Q + ++ +N E + +Q +++ Sbjct: 645 EAEELLDALDASDKKNEKLNNIINQYKENLDKLTQEHEEMEKAKNTAEKRVIIVQQDVKD 704 Query: 717 NMDLTDKLEKMS---AEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSK 773 + KLEK ++I++L ++I+ E + ++A + I+++ + Sbjct: 705 KEETIAKLEKDKNTLKDRITDLESRIDGLEGGNVDVSVVVNAATESYKKQIDDLNKTIQD 764 Query: 774 YKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDE------LVNRL 827 K + L + I +D R + +L S QE KA + + +DE VN L Sbjct: 765 AKDQEKDLRDEI---KDLRLDIVDLKGELESKEQEVNKAGDKLVLIDDENQSLKQTVNDL 821 Query: 828 AVLMDHDRVVEKQL--------LEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNAL 879 + + + +L L++ KE+++K + +NQ+LQ ++ + Sbjct: 822 KLKIKQSGDEKNELTMKIKYMELQMSAPQKEIEEKLNQEVMKNQDLQDEITSINTQLAEA 881 Query: 880 VEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESA 939 VEK ++ A E K Q + SN T++ KK E+E+ + Q+E Sbjct: 882 VEKRKASEAA-LEEMKEQMDGKIRNSNDLEATYQE---CFNKKTELENKVADLENQLE-I 936 Query: 940 IRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNI---ENLNMNVEELNKMNLELIDKHVQKQ 996 I+D + EK +K + +QL + + N + + + ++ +N+ L+L K+ Q + Sbjct: 937 IKDS--IEEKDDKIADLQSQLSSNSNDAVANDKLGDAMQLKIDTINRQYLDLKSKYDQLK 994 Query: 997 Q------TQSPDYTEQYIN---EINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYE 1047 ++ D E+ + E+ K+ ++K EI L +N + +D E Sbjct: 995 SDNLMVLSEKEDIEEELSSVKEEMTKMEGDYRKKAAEIEKLKHDVNFTKQVTGDDANDLE 1054 Query: 1048 SKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIP 1107 + E+ ++ M+ L +K N++L+ V E D+++ ++ E + Sbjct: 1055 KLQEDYDQLQEDYDDLME--DSDALTAK--NQQLEKRVTELTDEVEISQDKIKALEKQLR 1110 Query: 1108 KTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTE 1167 K ++ +E +DDA N D ++ +E +E+ + + ++E +L Sbjct: 1111 KQ-----NNELEDHADDAENADDDYVRMKADNDKIR-KERDEYRNKITEMEENMDQLKKT 1164 Query: 1168 LQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSA 1227 + E KI TEL G N E+ ++K++++Q+ END + + Sbjct: 1165 ITEQDIKI-------TELRGG---NGEEALKIKAQIKQIEEENDKEKEELLAKAQQFKTK 1214 Query: 1228 VDQRGFEIAELWKQHLAQREADFQKTEHELRVQ-LSAFESKYEQLLDSVQSSTQE---ET 1283 +++ + EL + + E +K + S +SK + L D ++ Q+ E Sbjct: 1215 MNKFKKQAQEL-AEKVEDLEGQLEKAKGSAAAAGASDLKSKIKDLQDEIEDVNQKLSSEK 1273 Query: 1284 NKIVTMEQ-VTSLQNKLQDKEEHLRNLQEK 1312 K +++ VTSL++ QDK+E + L++K Sbjct: 1274 EKSSRLQRKVTSLESDSQDKDEQIAKLKKK 1303 Score = 122 bits (294), Expect = 8e-26 Identities = 217/1117 (19%), Positives = 470/1117 (42%), Gaps = 85/1117 (7%) Query: 145 THLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXX 204 T L K+ D+ + +E T DL+ N+ +++ E K T Sbjct: 231 TELEEVEKDLDDEIKRHTATKADLEKTKNDLESSNNQINKLKEQLEK-TKAEKDENKNVA 289 Query: 205 XXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAAR 264 + +++++ +++ + ++ + Q L+ D++ K +R + E+ + E + Sbjct: 290 DQEVVTRKAVERKVSDLEKKVEGYKTDY-ETSQNLVNDLQVK-LRAVTKEKEDLEKEYSS 347 Query: 265 FEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSL--EIANMT 322 LE L Q ++ AK++ + + K +K +L EI + Sbjct: 348 GNNILE--VLQQSKQKGDEEIIKLHDDLAEQAKKTTDAMRDIKQLEYDKVALNGEITELN 405 Query: 323 -ELTKKIELLEHLNCQIRQT--NKEL-ENKLATMGTESKAVSSPSKKGSPLISRKSGRNT 378 EL K+ +L+ L +++Q +KEL E + G E+K +++ + ++ + Sbjct: 406 LELDKQKQLVTKLQQEVKQLQDDKELNEQDIRDAGFENKKLTNQINDAKEAMDKELMKEE 465 Query: 379 ASKMKSPWSQLSSETLNQDTDK---KINKNE--IAKLEMVIQSLNKDLV----DKEYVIS 429 K + + + +++ DK IN NE I +L+ + L ++L DKE + Sbjct: 466 KLKQEIQALKDTIAKNDEEHDKLESDINNNEKTIKQLQNANKVLTENLENCTRDKEAALR 525 Query: 430 EKDTXXXXXXXXXXGKDTLIA-QLQLEHQQ---HMEGPSLIH-VGTNTEDVNEIAKVQEQ 484 +K+ D L Q +L Q E L VGT + D+ + +Q Sbjct: 526 KKEQVETDLKEKSEEYDALNEKQRELNSQLVTLQKENAGLNETVGTISPDLKNTKALLKQ 585 Query: 485 LKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTI 544 ++EL D KD IE L E + + EI + +M +++ K Q+Q+ + Sbjct: 586 TQKELKD------AKDKIEGLTLDNEDLKKKQKEILEGHVSMEELEDYEK----QLQREV 635 Query: 545 DNFSKVSDSN-KEIVRLTEELHHLSQKVAEL-EEEKGNLQLHLVDYDSGRMIESDVYKKM 602 + SD +E++ + ++K+ + + K NL +++ ++ K++ Sbjct: 636 AKIKQKSDKEAEELLDALDASDKKNEKLNNIINQYKENLDKLTQEHEEMEKAKNTAEKRV 695 Query: 603 IEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSV 662 I ++ + + + I+ LE K L + L+ + D +E D+S + + S K + Sbjct: 696 IIVQQDVKDKEETIAKLEKDKNTLKDRITDLESRIDGLEGGNVDVSVVVNAATESYKKQI 755 Query: 663 H-LEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLT 721 L + I +K+L I++L+LD L G ++ E + +KL EN L Sbjct: 756 DDLNKTIQDAKDQEKDLRDEIKDLRLDIVDLKGELESKEQEVNKAGDKLVLIDDENQSLK 815 Query: 722 D-----KLE-KMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYK 775 KL+ K S ++ +EL KI + E Q I+ K+ + + ++++ E++ Sbjct: 816 QTVNDLKLKIKQSGDEKNELTMKIKYMELQMSAPQKEIEEKLNQEVMKNQDLQDEITSIN 875 Query: 776 SRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDR 835 +++ E E ++ + D + + Y E ++ EL N++A L + Sbjct: 876 TQLAEAVEKRKASEAALEEMKEQMDGKIRNSNDLEATYQECFNKKTELENKVADLENQLE 935 Query: 836 VVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTK 895 +++ + E + + +LQ + L N N ++ + ++ NR Sbjct: 936 IIKDSIEEKDDKIADLQSQ----LSSNSNDAVANDKLGDAMQLKIDTINR---------- 981 Query: 896 YQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEI--EFNTQIESAIRDKKVLNEKYEKN 953 Q DL+S ++ ++ ++ +K+ E+L E T++E R K EK + + Sbjct: 982 ---QYLDLKSKYDQLKSDNLMVLSEKEDIEEELSSVKEEMTKMEGDYRKKAAEIEKLKHD 1038 Query: 954 IEYVTQLEA----QLQEYKNNIENLNMNVEELNKMNLELIDKH--VQKQQTQSPDYTEQY 1007 + + Q+ L++ + + + L + ++L + + L K+ ++K+ T+ D E Sbjct: 1039 VNFTKQVTGDDANDLEKLQEDYDQLQEDYDDLMEDSDALTAKNQQLEKRVTELTDEVEIS 1098 Query: 1008 INEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYE---SKLAQFTTKLENMEEEM 1064 ++I L L++++ E+ NA Y+ M +D + + ++ K+ MEE M Sbjct: 1099 QDKIKALEKQLRKQNNELEDHADDAENADDDYVRMKADNDKIRKERDEYRNKITEMEENM 1158 Query: 1065 QRVSK-------QLLDSKQHNEELQILVREQDDQIKE---LKETKLTFEMNIPKTEGMII 1114 ++ K ++ + + N E + ++ Q QI+E ++ +L + KT+ Sbjct: 1159 DQLKKTITEQDIKITELRGGNGEEALKIKAQIKQIEEENDKEKEELLAKAQQFKTKMNKF 1218 Query: 1115 SSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTK 1174 + +++ +++ + + I++ LQ++ +N +L K Sbjct: 1219 KKQAQELAEKVEDLEGQLEKAKGSAAAAGASDLKSKIKD---LQDEIEDVNQKLSSEKEK 1275 Query: 1175 IIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTEND 1211 +L+ T L EQI +LK K++++ ++D Sbjct: 1276 SSRLQRKVTSLESDSQDKDEQIAKLKKKIKRMMVDDD 1312 Score = 104 bits (250), Expect = 2e-20 Identities = 194/1021 (19%), Positives = 427/1021 (41%), Gaps = 86/1021 (8%) Query: 575 EEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQ 634 EE +Q + +Y + + I ++K+ E + + + K + +++ +L Q L LQ Sbjct: 4 EEAISIIQSAIKEYCNQKSIWLKLFKEC-EKDLESYHKAKQLDGTKAEVGELEQTLIKLQ 62 Query: 635 QKYDEVEDKLAD----ISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKE 690 + +++++L I Q + E K+ ++++I +K L +EN K D Sbjct: 63 NENAKLKNELQTKEDVIKNYQKELTEVEEKNKGVDDRILEEKEKRKSAELELENKKDDIL 122 Query: 691 QLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQ 750 +L + +L+ + + +L+N +E + TDK K A + K+ E++ K++++ Sbjct: 123 ELQAMVSNLKQNLAGLQQELKNKEEEIITETDKSNKALAAQ------KVYQEQKEKLESE 176 Query: 751 FGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQ 810 D KI+ ++ + EL ++R E+ I + + R+A + + Sbjct: 177 LA-DVKIK-----LDTTQQELVATQARADGNEKEIEDITQEQNGWIRQAKEASKQIDSLN 230 Query: 811 KAYSEYTIQ-EDELVNRLAVLMDHDRVVEKQLLEIEHENKELQK-KNQI---LLEENQNL 865 E +DE+ A D +EK ++E N ++ K K Q+ E+++N Sbjct: 231 TELEEVEKDLDDEIKRHTATKAD----LEKTKNDLESSNNQINKLKEQLEKTKAEKDENK 286 Query: 866 QISLSDMQQHYNALVEKANRTDLAESESTKYQTQ---LRDLESNLKRITHEHQTL----- 917 ++ ++ + ++ E T Y+T + DL+ L+ +T E + L Sbjct: 287 NVADQEVVTRKAVERKVSDLEKKVEGYKTDYETSQNLVNDLQVKLRAVTKEKEDLEKEYS 346 Query: 918 -------IVQKKKEIEDLEI--------EFNTQIESAIRDKKVLN-EKYEKNIEYVTQLE 961 ++Q+ K+ D EI E + A+RD K L +K N E +T+L Sbjct: 347 SGNNILEVLQQSKQKGDEEIIKLHDDLAEQAKKTTDAMRDIKQLEYDKVALNGE-ITELN 405 Query: 962 AQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKL--NALLK 1019 +L + K + L V++L + EL ++ ++ ++ T Q IN+ + L+K Sbjct: 406 LELDKQKQLVTKLQQEVKQLQD-DKELNEQDIRDAGFENKKLTNQ-INDAKEAMDKELMK 463 Query: 1020 QK--DEEIIALNQKINNAQVSYMSMVSDY---ESKLAQFTTKLENMEEEMQRVSKQLLDS 1074 ++ +EI AL I + + SD E + Q + + E ++ ++ + Sbjct: 464 EEKLKQEIQALKDTIAKNDEEHDKLESDINNNEKTIKQLQNANKVLTENLENCTRDKEAA 523 Query: 1075 KQHNEELQILVREQDDQIKEL--KETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXX 1132 + E+++ ++E+ ++ L K+ +L ++ + E ++ T+ +S D N Sbjct: 524 LRKKEQVETDLKEKSEEYDALNEKQRELNSQLVTLQKENAGLNETVGTISPDLKNTKALL 583 Query: 1133 XXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVN 1192 ++++ ++ I+ ++ E K E+ E + + +LE +L Sbjct: 584 KQTQK-----ELKDAKDKIEGLTLDNEDLKKKQKEILEGHVSMEELEDYEKQL------- 631 Query: 1193 QEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQK 1252 Q ++ ++K K ++ E + L + +++ ++Q + +L ++H E + K Sbjct: 632 QREVAKIKQKSDKEAEELLDALDASDKKNEKLNNIINQYKENLDKLTQEH---EEMEKAK 688 Query: 1253 TEHELRVQLSAFESK-YEQLLDSVQSSTQEETNKIVTME-QVTSLQNKLQDKEEHLRNLQ 1310 E RV + + K E+ + ++ ++I +E ++ L+ D + Sbjct: 689 NTAEKRVIIVQQDVKDKEETIAKLEKDKNTLKDRITDLESRIDGLEGGNVDVSVVVNAAT 748 Query: 1311 EKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNI 1370 E Y I+ + + +D++ +L ++ Q + ++ +L I Sbjct: 749 ESYKKQIDDLNKTIQDAKDQEKDLRDEIKDLRLDIVDLKGELESKEQEVNKAGDKLVL-I 807 Query: 1371 NEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQR 1430 ++EN LK++ N+ K+ + Q+ EI +K ++ + Sbjct: 808 DDENQSLKQTVNDLKLKIKQSGDEKNELTMKIKYMELQMSAPQKEIEEKLNQEVMKNQDL 867 Query: 1431 NDEFENVRQQLVE-YEKRIED---LTYEKESELAILRLKMHENANHYETMQKESEIE-RV 1485 DE ++ QL E EKR L KE +R A + E K++E+E +V Sbjct: 868 QDEITSINTQLAEAVEKRKASEAALEEMKEQMDGKIRNSNDLEATYQECFNKKTELENKV 927 Query: 1486 KLIEELNVKITESV-SLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQ 1544 +E I +S+ + ++A+L L + +++I T+N + +L+ Sbjct: 928 ADLENQLEIIKDSIEEKDDKIADLQSQLSSNSNDAVANDKLGDAMQLKIDTINRQYLDLK 987 Query: 1545 N 1545 + Sbjct: 988 S 988 Score = 103 bits (246), Expect = 5e-20 Identities = 190/1063 (17%), Positives = 445/1063 (41%), Gaps = 90/1063 (8%) Query: 536 KLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDS----- 590 K KQ+ T ++V + + +++L E L ++ E+ N Q L + + Sbjct: 40 KAKQLDGTK---AEVGELEQTLIKLQNENAKLKNELQTKEDVIKNYQKELTEVEEKNKGV 96 Query: 591 -GRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQ 649 R++E +K E+E E + I L++ +L Q L LQQ+ E+++ I++ Sbjct: 97 DDRILEEKEKRKSAELE--LENKKDDILELQAMVSNLKQNLAGLQQELKNKEEEI--ITE 152 Query: 650 LQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNK 709 + V+ +EQ + L + ++ + ++ + + E + EDI + Sbjct: 153 TDKSNKALAAQKVY-QEQKEKLESELADVKIKLDTTQQELVATQARADGNEKEIEDITQE 211 Query: 710 LQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIES 769 +I++ + + +++ ++ E L ++ + +I+ A +++ +E+ + Sbjct: 212 QNGWIRQAKEASKQIDSLNTE-----LEEVEKDLDDEIKRHTATKADLEKTKNDLESSNN 266 Query: 770 ELSKYKSRICRLE---ESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNR 826 +++K K ++ + + + + D+ + ++ S L++K + Y LVN Sbjct: 267 QINKLKEQLEKTKAEKDENKNVADQEVVTRKAVERKVSDLEKKVEGYKTDYETSQNLVND 326 Query: 827 LAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRT 886 L V + R V K+ ++E KE N IL Q+ Q ++ + ++ L E+A +T Sbjct: 327 LQVKL---RAVTKEKEDLE---KEYSSGNNILEVLQQSKQKGDEEIIKLHDDLAEQAKKT 380 Query: 887 DLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVL 946 T ++ LE + + E L ++ K+ + L + +++ ++D K L Sbjct: 381 -------TDAMRDIKQLEYDKVALNGEITELNLELDKQ-KQLVTKLQQEVKQ-LQDDKEL 431 Query: 947 NEKYEKNIEYVTQ-LEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTE 1005 NE+ ++ + + L Q+ + K ++ M E+L K ++ + + K + D E Sbjct: 432 NEQDIRDAGFENKKLTNQINDAKEAMDKELMKEEKL-KQEIQALKDTIAKNDEEH-DKLE 489 Query: 1006 QYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQ 1065 IN K L+ ++ + + + + + E+ L + + + + + E+ + Sbjct: 490 SDINNNEKTIKQLQNANKVLTENLENCTRDKEAALRKKEQVETDLKEKSEEYDALNEKQR 549 Query: 1066 RVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDA 1125 ++ QL+ ++ N L V +K K + + + I T++ Sbjct: 550 ELNSQLVTLQKENAGLNETVGTISPDLKNTKALLKQTQKELKDAKDKIEGLTLD------ 603 Query: 1126 NNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTEL 1185 N D + ++E E++ ++ LQ + AK+ + + ++ L+ L+ Sbjct: 604 -NEDLKKKQKEILEGHVSMEELEDYEKQ---LQREVAKIKQKSDKEAEEL--LDALDASD 657 Query: 1186 TGHDVVNQEQINQLKSKLEQLNTENDNL--LSTVAELRSSI-SSAVDQRGFEIAELWKQH 1242 ++ +N INQ K L++L E++ + AE R I V + IA+L K Sbjct: 658 KKNEKLNNI-INQYKENLDKLTQEHEEMEKAKNTAEKRVIIVQQDVKDKEETIAKLEKDK 716 Query: 1243 --LAQREADFQKT-------EHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQ-- 1291 L R D + ++ V ++A Y++ +D + + Q+ ++ + Sbjct: 717 NTLKDRITDLESRIDGLEGGNVDVSVVVNAATESYKKQIDDLNKTIQDAKDQEKDLRDEI 776 Query: 1292 ------VTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXX 1345 + L+ +L+ KE+ + +K + ++ + L+ + D K+ Sbjct: 777 KDLRLDIVDLKGELESKEQEVNKAGDKLVLIDDENQSLKQTVNDLKLKIKQSGDEKNELT 836 Query: 1346 XXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLEL 1405 + K+++E+ + + N L+ + +EA + E+ Sbjct: 837 MKIKYMELQMSAPQKEIEEKLNQEVMK-NQDLQDEITSINTQLAEAVEKRKASEAALEEM 895 Query: 1406 THQLE--LKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILR 1463 Q++ +++S + T++ + E EN L + I+D EK+ ++A L+ Sbjct: 896 KEQMDGKIRNSNDLEATYQECFN---KKTELENKVADLENQLEIIKDSIEEKDDKIADLQ 952 Query: 1464 LKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQ 1523 ++ N+N + KL + + +KI ++N+Q +L ++ + + Sbjct: 953 SQLSSNSN--------DAVANDKLGDAMQLKID---TINRQYLDLKSKYDQLKSDNLMVL 1001 Query: 1524 TALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQ 1566 + E+ E E+ ++ +E+T ++ R +++I+K + TKQ Sbjct: 1002 SEKEDIEEELSSVKEEMTKMEGDYRKKAAEIEKLKHDVNFTKQ 1044 Score = 93.5 bits (222), Expect = 4e-17 Identities = 139/786 (17%), Positives = 330/786 (41%), Gaps = 43/786 (5%) Query: 793 YSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQ 852 Y ++ D + + E ++ + + +L N L D + +K+L E+E +NK + Sbjct: 38 YHKAKQLDGTKAEVGELEQTLIKLQNENAKLKNELQTKEDVIKNYQKELTEVEEKNKGVD 97 Query: 853 KKNQILLEENQNLQISLSDMQQ---HYNALVE--KANRTDLAESESTKYQTQLRDLESNL 907 + E+ ++ ++ L + + A+V K N L + K + + + + + Sbjct: 98 DRILEEKEKRKSAELELENKKDDILELQAMVSNLKQNLAGLQQELKNKEEEIITETDKSN 157 Query: 908 KRITHE--HQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLE---- 961 K + + +Q + + E+ D++I+ +T + + + + EK IE +TQ + Sbjct: 158 KALAAQKVYQEQKEKLESELADVKIKLDTTQQELVATQARADGN-EKEIEDITQEQNGWI 216 Query: 962 AQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQT--QSPDYTEQYINEINKLNALLK 1019 Q +E I++LN +EE+ K + I +H + ++ + E N+INKL L+ Sbjct: 217 RQAKEASKQIDSLNTELEEVEKDLDDEIKRHTATKADLEKTKNDLESSNNQINKLKEQLE 276 Query: 1020 ----QKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSK 1075 +KDE +Q++ + + VSD E K+ + T E + + + +L Sbjct: 277 KTKAEKDENKNVADQEVVTRK-AVERKVSDLEKKVEGYKTDYETSQNLVNDLQVKLRAVT 335 Query: 1076 QHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISS---TIEPMSDDAN-NVDXX 1131 + E+L+ ++ ++ L+++K + I K + T + M D D Sbjct: 336 KEKEDLEKEYSSGNNILEVLQQSKQKGDEEIIKLHDDLAEQAKKTTDAMRDIKQLEYDKV 395 Query: 1132 XXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVV 1191 L++ ++++ + + LQ++ +L + + I N +LT Sbjct: 396 ALNGEITELNLELDKQKQLVTK---LQQEVKQLQDDKELNEQDIRDAGFENKKLTN---- 448 Query: 1192 NQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQ 1251 QIN K +++ + + L + L+ +I+ ++ + + + E + Sbjct: 449 ---QINDAKEAMDKELMKEEKLKQEIQALKDTIAKNDEEH-----DKLESDINNNEKTIK 500 Query: 1252 KTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQE 1311 + ++ +V E+ +++ Q ET+ E+ +L K ++ L LQ+ Sbjct: 501 QLQNANKVLTENLENCTRDKEAALRKKEQVETDLKEKSEEYDALNEKQRELNSQLVTLQK 560 Query: 1312 KYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNIN 1371 + A + + + ++++ K A L +N+ K+ Q++ IL + Sbjct: 561 ENAGLNETVGTISPDLKNTK-ALLKQTQKELKDAKDKIEGLTLDNEDLKKKQKE-ILEGH 618 Query: 1372 EENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRN 1431 +L+ + + ++L+ + K+ ++ ++Y L + Sbjct: 619 VSMEELEDYEKQLQREVAKIKQKSDKEAEELLDALDASDKKNEKLNNIINQYKENLDKLT 678 Query: 1432 DEFENVRQQLVEYEKRIEDLTYE-KESELAILRLKMHENANHYETMQKESEIERVKLIE- 1489 E E + + EKR+ + + K+ E I +L+ +N ES I+ ++ Sbjct: 679 QEHEEMEKAKNTAEKRVIIVQQDVKDKEETIAKLEKDKNTLKDRITDLESRIDGLEGGNV 738 Query: 1490 ELNVKITESV-SLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVR 1548 +++V + + S KQ+ +LNK +++ + +++ +++ ++IV L E+ + + V Sbjct: 739 DVSVVVNAATESYKKQIDDLNKTIQDAKDQEKDLRDEIKDLRLDIVDLKGELESKEQEVN 798 Query: 1549 ASSSKI 1554 + K+ Sbjct: 799 KAGDKL 804 Score = 58.0 bits (134), Expect = 2e-06 Identities = 120/603 (19%), Positives = 255/603 (42%), Gaps = 64/603 (10%) Query: 144 VTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXX 203 + L+ TI++ + L+ ++K + I+DL+ ++ K+Q + NKA Sbjct: 755 IDDLNKTIQDAKDQEKDLRDEIKDLRLDIVDLKGELESKEQEV---NKAGDKLVLI---- 807 Query: 204 XXXXXXXXEDTKQQMTKMQENFIAMEAEWK-DEKQRLLKDIESKDVRISSLEEANKLLEA 262 D + Q K N + ++ + DEK L I+ ++++S+ ++ ++ E Sbjct: 808 ---------DDENQSLKQTVNDLKLKIKQSGDEKNELTMKIKYMELQMSAPQK--EIEEK 856 Query: 263 ARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMT 322 E+ +++ L E+ +++ E + EE E + G + +N Sbjct: 857 LNQEV-MKNQDLQDEITSINTQLAEAVE-----KRKASEAALEEMKE-QMDGKIRNSNDL 909 Query: 323 ELTKKIELLEHLNCQIRQTNK--ELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTAS 380 E T + E N + NK +LEN+L + + +S S A+ Sbjct: 910 EATYQ----ECFNKKTELENKVADLENQLEIIKDSIEEKDDKIADLQSQLSSNSNDAVAN 965 Query: 381 KMKSPWSQLSSETLN-QDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXX 439 QL +T+N Q D K +++ +++ S +D+ ++ + E+ T Sbjct: 966 DKLGDAMQLKIDTINRQYLDLKSKYDQLKSDNLMVLSEKEDIEEELSSVKEEMTKMEG-- 1023 Query: 440 XXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVK 499 D ++E +H + G + D+ ++ + +QL+++ +D ++D + Sbjct: 1024 ------DYRKKAAEIEKLKHDVNFTKQVTGDDANDLEKLQEDYDQLQEDYDDLMEDSDA- 1076 Query: 500 DLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVR 559 L K + E+++T+L DE++ + K+K+ K KQ + D+ +++ + VR Sbjct: 1077 -LTAKNQQLEKRVTELTDEVEISQD---KIKALEKQLRKQNNELEDHADDAENADDDYVR 1132 Query: 560 LTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLL 619 + + + K+ + +E N + + D KK I +++ T L+ + Sbjct: 1133 MKAD----NDKIRKERDEYRNKITEMEE-------NMDQLKKTITEQDIKITELRGGNGE 1181 Query: 620 ESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELA 679 E+ K Q I ++ E E+ LA Q ++ + ++ L E+++ L ++ Sbjct: 1182 EALKIK-AQIKQIEEENDKEKEELLAKAQQFKTKMNKFKKQAQELAEKVEDLEGQLEKAK 1240 Query: 680 LVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDK---LEKMSAEKISELL 736 L IKDL+++ ED+ KL + +++ L K LE S +K E + Sbjct: 1241 --GSAAAAGASDLKSKIKDLQDEIEDVNQKLSSEKEKSSRLQRKVTSLESDSQDK-DEQI 1297 Query: 737 AKI 739 AK+ Sbjct: 1298 AKL 1300 >UniRef50_P25386 Cluster: Intracellular protein transport protein USO1; n=3; Saccharomyces cerevisiae|Rep: Intracellular protein transport protein USO1 - Saccharomyces cerevisiae (Baker's yeast) Length = 1790 Score = 139 bits (336), Expect = 7e-31 Identities = 214/1024 (20%), Positives = 446/1024 (43%), Gaps = 88/1024 (8%) Query: 159 SVLQVKMKIMETTILDLQEKINEKDQ---IIEAKNKATTXXXXXXXXXXXXXXXXXEDTK 215 S L+ I+ET + ++++ ++E Q ++E K+K ED+ Sbjct: 786 SSLKENFSILETELKNVRDSLDEMTQLRDVLETKDKENQTALLEYKSTIHKQ----EDSI 841 Query: 216 QQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLA 275 + + K E ++ + + +D ++ KD+ + + ++EE K L+ + + ++ H K Sbjct: 842 KTLEKGLETILSQKKKAEDGINKMGKDLFALSREMQAVEENCKNLQKEKDKSNVNHQKET 901 Query: 276 QEL-EQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHL 334 + L E L + I+ C ++ +E S E + E + + ++L Sbjct: 902 KSLKEDIAAKITEIKAINENLEEMKIQ--CNNLSKEKEHISKE---LVEYKSRFQSHDNL 956 Query: 335 NCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETL 394 ++ + K L N M E++++ ++ S+ S +++ +S E Sbjct: 957 VAKLTEKLKSLANNYKDMQAENESLIKAVEE-----SKNESSIQLSNLQNKIDSMSQEKE 1011 Query: 395 NQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQL 454 N ++ + I +L+ I L + KE +IS+ D+ L +L+ Sbjct: 1012 NFQIERGSIEKNIEQLKKTISDLEQ---TKEEIISKSDSSKDEYESQI---SLLKEKLET 1065 Query: 455 EHQQHMEGPSLIHVGTNT-EDVNEIAKVQEQLKQELNDE-------IKDV--NVKDLIEK 504 + E + I T T E++ + LK EL + +K+V N + L E+ Sbjct: 1066 ATTANDENVNKISELTKTREELEAELAAYKNLKNELETKLETSEKALKEVKENEEHLKEE 1125 Query: 505 LKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNF-SKVSDSNKEIVRLTEE 563 E++ T+ ++++ N+ ++ H+ Q++K + +K N+EI +L +E Sbjct: 1126 KIQLEKEATETKQQLNSLRANLESLEKEHEDLAAQLKKYEEQIANKERQYNEEISQLNDE 1185 Query: 564 LHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLK------AIS 617 + Q+ ++++ L+ + S +S++ K I+ NL LK S Sbjct: 1186 ITSTQQENESIKKKNDELEGEVKAMKSTSEEQSNLKKSEIDALNLQIKELKKKNETNEAS 1245 Query: 618 LLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIK-SVHLEEQIDALSASKK 676 LLES K + E +++ DE K ++S+L+ SE K S +LE Q ++ K+ Sbjct: 1246 LLESIK-SVESETVKIKELQDECNFKEKEVSELEDKLKASEDKNSKYLELQKES-EKIKE 1303 Query: 677 ELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAE-----K 731 EL LK+ E++ K E + ++ + +E + ++LEK+ E + Sbjct: 1304 ELDAKTTELKIQLEKITNLSKAKEKSESELSRLKKTSSEERKNAEEQLEKLKNEIQIKNQ 1363 Query: 732 ISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLE-ESIAVMED 790 E K+ +E S I ++ E +L E+EL + R E E +++ D Sbjct: 1364 AFEKERKLLNEGSSTITQEYSEKINTLEDELIRLQNENELKAKEIDNTRSELEKVSLSND 1423 Query: 791 RRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVE--KQLLEIEHEN 848 LE K + + S LQ++ +Y + + DE + L++ D+ R +E K+ L E+ Sbjct: 1424 E--LLEEKQNTIKS-LQDEILSYKDKITRNDEKL--LSIERDNKRDLESLKEQLRAAQES 1478 Query: 849 K-ELQKKNQILLEENQNLQISL---SDMQQHYNALVEKANRTDLAESEST------KYQT 898 K ++++ + L EE+ + L +M + + +E +N T+L S T K + Sbjct: 1479 KAKVEEGLKKLEEESSKEKAELEKSKEMMKKLESTIE-SNETELKSSMETIRKSDEKLEQ 1537 Query: 899 QLRDLESNLKRITHEHQTLIV---QKKKEIEDL------EIEFNTQIESAIRDKKVLNEK 949 + E ++K + HE LI + +K+IE+L E + +++E+ ++ EK Sbjct: 1538 SKKSAEEDIKNLQHEKSDLISRINESEKDIEELKSKLRIEAKSGSELETVKQELNNAQEK 1597 Query: 950 YEKNIEYVTQLEAQLQEYKNNIEN------LNMNVEELNKMNLELIDKHVQKQQTQSPDY 1003 N E T L+++L++ + +++ N +EL L+ +++ + Q ++ Sbjct: 1598 IRINAEENTVLKSKLEDIERELKDKQAEIKSNQEEKELLTSRLKELEQELDSTQQKAQKS 1657 Query: 1004 TEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEE 1063 E+ E+ K Q DE+ + L K N+ + D ++ + TT ++ +E Sbjct: 1658 EEERRAEVRKFQVEKSQLDEKAMLLETKYNDLVNKEQAWKRDEDT--VKKTT--DSQRQE 1713 Query: 1064 MQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSD 1123 +++++K+L + K N +L+ E +I +L + K + +E SD Sbjct: 1714 IEKLAKELDNLKAENSKLK-EANEDRSEIDDLMLLVTDLDEKNAKYRSKLKDLGVEISSD 1772 Query: 1124 DANN 1127 + ++ Sbjct: 1773 EEDD 1776 Score = 136 bits (330), Expect = 4e-30 Identities = 180/916 (19%), Positives = 413/916 (45%), Gaps = 81/916 (8%) Query: 486 KQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTID 545 KQE + + + ++ ++ + K AE+ I ++ ++ A ++ M V+ N K K+ K+ Sbjct: 836 KQEDSIKTLEKGLETILSQKKKAEDGINKMGKDLFALSREMQAVEENCKNLQKEKDKSNV 895 Query: 546 NFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEM 605 N K + S KE ++ K+ E++ NL+ + ++ + + K+++E Sbjct: 896 NHQKETKSLKE---------DIAAKITEIKAINENLEEMKIQCNNLSKEKEHISKELVEY 946 Query: 606 ENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLE 665 ++ ++ ++ L + L +Q + + + I ++ + S I+ +L+ Sbjct: 947 KSRFQSHDNLVAKLTEKLKSLANNYKDMQAENESL------IKAVEESKNESSIQLSNLQ 1000 Query: 666 EQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQN----YIQENMDLT 721 +ID++S K+ + +++ + EQL TI DLE KE+I++K + Y + L Sbjct: 1001 NKIDSMSQEKENFQIERGSIEKNIEQLKKTISDLEQTKEEIISKSDSSKDEYESQISLLK 1060 Query: 722 DKLEKM------SAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYK 775 +KLE + KISE L K E ++++ + +++ + +E E L + K Sbjct: 1061 EKLETATTANDENVNKISE-LTKTREELEAELAAYKNLKNELETK---LETSEKALKEVK 1116 Query: 776 SRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQ----EDELVNRLAVLM 831 L+E +E +++ + L + L+ +K + + Q E+++ N+ Sbjct: 1117 ENEEHLKEEKIQLEKEATETKQQLNSLRANLESLEKEHEDLAAQLKKYEEQIANKERQYN 1176 Query: 832 DHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAES 891 + + ++ + EN+ ++KKN L E + ++ S S+ Q + A + E Sbjct: 1177 EEISQLNDEITSTQQENESIKKKNDELEGEVKAMK-STSEEQSNLKKSEIDALNLQIKEL 1235 Query: 892 ESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKY- 950 + K +T L ++K + E +T+ +++ ++ + + + +++E ++ + N KY Sbjct: 1236 KK-KNETNEASLLESIKSV--ESETVKIKELQDECNFKEKEVSELEDKLKASEDKNSKYL 1292 Query: 951 --EKNIEYV-TQLEAQLQEYKNNIENL-NMN-VEELNKMNLELIDKHVQKQQTQSPDYTE 1005 +K E + +L+A+ E K +E + N++ +E ++ L + K +++ + + E Sbjct: 1293 ELQKESEKIKEELDAKTTELKIQLEKITNLSKAKEKSESELSRLKKTSSEERKNAEEQLE 1352 Query: 1006 QYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQ 1065 + NEI N +K+ ++ LN+ + Y ++ E +L + + E +E+ Sbjct: 1353 KLKNEIQIKNQAF-EKERKL--LNEGSSTITQEYSEKINTLEDELIRLQNENELKAKEID 1409 Query: 1066 RVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDA 1125 +L N+E L+ E+ + IK L++ L+++ I + + ++S IE D+ Sbjct: 1410 NTRSELEKVSLSNDE---LLEEKQNTIKSLQDEILSYKDKITRNDEKLLS--IE--RDNK 1462 Query: 1126 NNVDXXXXXXXXXXXXLKVQEEEEFIQE-RSVLQEQSAKLNTELQECYTKIIQLETLNTE 1184 +++ QE + ++E L+E+S+K EL++ + +LE+ Sbjct: 1463 RDLESLKEQLRA------AQESKAKVEEGLKKLEEESSKEKAELEKSKEMMKKLES---- 1512 Query: 1185 LTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLA 1244 + + E +LKS +E + ++ L + I + ++ I+ + Sbjct: 1513 ----TIESNE--TELKSSMETIRKSDEKLEQSKKSAEEDIKNLQHEKSDLIS-----RIN 1561 Query: 1245 QREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKI-VTMEQVTSLQNKLQDKE 1303 + E D ++ + +LR+ E+K L++V+ KI + E+ T L++KL+D E Sbjct: 1562 ESEKDIEELKSKLRI-----EAKSGSELETVKQELNNAQEKIRINAEENTVLKSKLEDIE 1616 Query: 1304 EHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQ 1363 L++ Q + + E+L S +++ + ++R Q+ Sbjct: 1617 RELKDKQAEIKSNQEEKELLTSRLKELEQELDSTQQKAQKSEEERRAEVRKFQVEKSQLD 1676 Query: 1364 EQSILNINEENAQLKK 1379 E+++L + N + K Sbjct: 1677 EKAMLLETKYNDLVNK 1692 Score = 113 bits (272), Expect = 4e-23 Identities = 176/829 (21%), Positives = 362/829 (43%), Gaps = 88/829 (10%) Query: 833 HDRVVEKQLLEIEHENKELQKKNQIL------LEEN--------QNLQISLSDMQQHYNA 878 H+ + EK L+ + +E+KEL +K QIL L+EN +N++ SL +M Q + Sbjct: 757 HENLTEK-LIALTNEHKELDEKYQILNSSHSSLKENFSILETELKNVRDSLDEMTQLRDV 815 Query: 879 L--VEKANRTDLAESEST--KYQTQLRDLESNLKRITHEHQTL---IVQKKKEIEDLEIE 931 L +K N+T L E +ST K + ++ LE L+ I + + I + K++ L E Sbjct: 816 LETKDKENQTALLEYKSTIHKQEDSIKTLEKGLETILSQKKKAEDGINKMGKDLFALSRE 875 Query: 932 FNTQIESAIRDKKVLNEKYEKNIEY---VTQLEAQLQEYKNNIENLNMNVEELNKM--NL 986 E+ K + EK + N+ + L+ + I+ +N N+EE+ NL Sbjct: 876 MQAVEENC---KNLQKEKDKSNVNHQKETKSLKEDIAAKITEIKAINENLEEMKIQCNNL 932 Query: 987 ELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQ----------KDEEII-ALNQKINNA 1035 +H+ K+ + + + N + KL LK ++E +I A+ + N + Sbjct: 933 SKEKEHISKELVEYKSRFQSHDNLVAKLTEKLKSLANNYKDMQAENESLIKAVEESKNES 992 Query: 1036 QVSYMSMVSDYES---KLAQFTTKLENMEEEMQRVSKQLLDSKQHNEEL----QILVREQ 1088 + ++ + +S + F + ++E+ ++++ K + D +Q EE+ E Sbjct: 993 SIQLSNLQNKIDSMSQEKENFQIERGSIEKNIEQLKKTISDLEQTKEEIISKSDSSKDEY 1052 Query: 1089 DDQIKELKETKLTFEMNIPKTEGMI--ISSTIEPMSDD----ANNVDXXXXXXXXXXXXL 1142 + QI LKE T + I ++ T E + + N + L Sbjct: 1053 ESQISLLKEKLETATTANDENVNKISELTKTREELEAELAAYKNLKNELETKLETSEKAL 1112 Query: 1143 K-VQEEEEFIQERSV-LQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQI-NQL 1199 K V+E EE ++E + L++++ + +L + LE + +L +EQI N+ Sbjct: 1113 KEVKENEEHLKEEKIQLEKEATETKQQLNSLRANLESLEKEHEDLAAQLKKYEEQIANKE 1172 Query: 1200 KSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHE-LR 1258 + E+++ ND + ST E SI D+ E+ + + ++ +++ +K+E + L Sbjct: 1173 RQYNEEISQLNDEITSTQQE-NESIKKKNDELEGEVKAM--KSTSEEQSNLKKSEIDALN 1229 Query: 1259 VQLSAFESKYE----QLLDSVQSSTQEETNKIVTMEQVTSLQNK----LQDKEEHLRNLQ 1310 +Q+ + K E LL+S++ S + ET KI ++ + + K L+DK + + Sbjct: 1230 LQIKELKKKNETNEASLLESIK-SVESETVKIKELQDECNFKEKEVSELEDKLKASEDKN 1288 Query: 1311 EKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNI 1370 KY ++ + E ++ E+ D K +E K+ + N Sbjct: 1289 SKYLELQKESEKIKEEL-DAKTTELKIQLEKITNLSKAKEKSESELSRLKKTSSEERKNA 1347 Query: 1371 NEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVL-ELTHQLELKDSEIYQKTHEYTITLTQ 1429 E+ +LK +N+ + + E + ++ + E+ + +E + Sbjct: 1348 EEQLEKLKNEIQIKNQAFEKERKLLNEGSSTITQEYSEKINTLEDELIRLQNENEL---- 1403 Query: 1430 RNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIE 1489 + E +N R +L + ++L EK++ + L+ E ++ + + + E++ IE Sbjct: 1404 KAKEIDNTRSELEKVSLSNDELLEEKQNTIKSLQ---DEILSYKDKITRND--EKLLSIE 1458 Query: 1490 ELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIE-----IVTLNDEITNLQ 1544 N + ES+ + A+ +KA EE K E +++ E E+E + L I + + Sbjct: 1459 RDNKRDLESLKEQLRAAQESKAKVEEGLKKLEEESSKEKAELEKSKEMMKKLESTIESNE 1518 Query: 1545 NMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNK--ELLDAVPRAELDL 1591 +++S I+K +K+ +E + N ++ +L+ + +E D+ Sbjct: 1519 TELKSSMETIRKSDEKLEQSKKSAEEDIKNLQHEKSDLISRINESEKDI 1567 Score = 111 bits (267), Expect = 2e-22 Identities = 197/1087 (18%), Positives = 463/1087 (42%), Gaps = 69/1087 (6%) Query: 212 EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271 E ++Q TK++ +++ E + + L + + + L+E ++L ++ + Sbjct: 733 EKLQRQCTKLKGEITSLQTETESTHENLTEKLIALTNEHKELDEKYQILNSSHSSLKENF 792 Query: 272 SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSL--EIANMTELTKKIE 329 S L EL+ L + E + +E K ++ + ++ L K +E Sbjct: 793 SILETELKNVRDSLDEMTQLRDVLETKDKE---NQTALLEYKSTIHKQEDSIKTLEKGLE 849 Query: 330 LLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQL 389 + + ++ L + E +AV + K KS N + KS + Sbjct: 850 TILSQKKKAEDGINKMGKDLFALSREMQAVEE-NCKNLQKEKDKSNVNHQKETKSLKEDI 908 Query: 390 SS-----ETLNQDTDK-KINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXX 443 ++ + +N++ ++ KI N ++K + + ++K+LV+ + D Sbjct: 909 AAKITEIKAINENLEEMKIQCNNLSKEK---EHISKELVEYKSRFQSHDNLVAKLTEKLK 965 Query: 444 GKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIE 503 +Q E++ ++ ++ + N K+ +++ N +I+ +++ IE Sbjct: 966 SLANNYKDMQAENESLIKAVEESKNESSIQLSNLQNKIDSMSQEKENFQIERGSIEKNIE 1025 Query: 504 KLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSN-KEIVRLTE 562 +LK + Q +EI + + + K ++ ++ +++ ++ + +D N +I LT+ Sbjct: 1026 QLKKTISDLEQTKEEIISKSDSS---KDEYESQISLLKEKLETATTANDENVNKISELTK 1082 Query: 563 ELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQ 622 L ++A + K L+ L E + + E+L E +++ LE + Sbjct: 1083 TREELEAELAAYKNLKNELETKL------ETSEKALKEVKENEEHLKEEKIQ----LEKE 1132 Query: 623 KFDLVQELHILQQKYDEVEDKLADI-SQLQSDQVCSEIKSVHLEEQIDALSASKKELALV 681 + Q+L+ L+ + +E + D+ +QL+ + K E+I L+ Sbjct: 1133 ATETKQQLNSLRANLESLEKEHEDLAAQLKKYEEQIANKERQYNEEISQLNDEITSTQQE 1192 Query: 682 IENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQE-NMDLTDKLEKMSAEKISELLAKIN 740 E++K ++L G +K +++ E+ N ++ I N+ + + L+K + + LL I Sbjct: 1193 NESIKKKNDELEGEVKAMKSTSEEQSNLKKSEIDALNLQIKE-LKKKNETNEASLLESIK 1251 Query: 741 HEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKAD 800 E ++ + + + ++ + +E +L + + + E E + L+ K Sbjct: 1252 SVESETVKIK-ELQDECNFKEKEVSELEDKLKASEDKNSKYLELQKESEKIKEELDAKTT 1310 Query: 801 QLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLE 860 +L L++ E EL + + E+QL ++++ E+Q KNQ + Sbjct: 1311 ELKIQLEKITNLSKAKEKSESELSRLKKTSSEERKNAEEQLEKLKN---EIQIKNQAFEK 1367 Query: 861 ENQNLQISLSDMQQHYNALVEK-ANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIV 919 E + L S + Q Y+ + + ++E+ ++ + S L++++ + L+ Sbjct: 1368 ERKLLNEGSSTITQEYSEKINTLEDELIRLQNENELKAKEIDNTRSELEKVSLSNDELLE 1427 Query: 920 QKKKEIEDLEIEFNTQIESAIR-DKKVLN--EKYEKNIEYVTQLEAQLQEYKNNI-ENLN 975 +K+ I+ L+ E + + R D+K+L+ ++++E + + QE K + E L Sbjct: 1428 EKQNTIKSLQDEILSYKDKITRNDEKLLSIERDNKRDLESLKEQLRAAQESKAKVEEGLK 1487 Query: 976 MNVEELNKMNLEL-IDKHVQK--QQTQSPDYTE--QYINEINKLNALLKQKDEEIIALNQ 1030 EE +K EL K + K + T + TE + I K + L+Q + + Sbjct: 1488 KLEEESSKEKAELEKSKEMMKKLESTIESNETELKSSMETIRKSDEKLEQSKKSAEEDIK 1547 Query: 1031 KINNAQVSYMSMVSDYESKLAQFTTKLE---NMEEEMQRVSKQLLDSKQ----HNEELQI 1083 + + + +S +++ E + + +KL E++ V ++L ++++ + EE + Sbjct: 1548 NLQHEKSDLISRINESEKDIEELKSKLRIEAKSGSELETVKQELNNAQEKIRINAEENTV 1607 Query: 1084 LVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLK 1143 L + +D +ELK+ + + N + E +++S ++ + + ++ + Sbjct: 1608 LKSKLEDIERELKDKQAEIKSN--QEEKELLTSRLKELEQELDSTQQKAQKSEEE----R 1661 Query: 1144 VQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKL 1203 E +F E+S L E++ L T+ Y ++ E D V + +Q + ++ Sbjct: 1662 RAEVRKFQVEKSQLDEKAMLLETK----YNDLVNKE--QAWKRDEDTVKKTTDSQ-RQEI 1714 Query: 1204 EQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSA 1263 E+L E DNL + ++L+ + D+ + L L ++ A ++ +L V++S+ Sbjct: 1715 EKLAKELDNLKAENSKLKEANE---DRSEIDDLMLLVTDLDEKNAKYRSKLKDLGVEISS 1771 Query: 1264 FESKYEQ 1270 E E+ Sbjct: 1772 DEEDDEE 1778 Score = 91.9 bits (218), Expect = 1e-16 Identities = 129/617 (20%), Positives = 265/617 (42%), Gaps = 59/617 (9%) Query: 979 EELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVS 1038 E +NK++ E ++K +Q+Q T+ E + L +K +IAL + Sbjct: 722 EPINKISFEEVEK-LQRQCTKLKGEITSLQTETESTHENLTEK---LIALTNEHKELDEK 777 Query: 1039 YMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKET 1098 Y + S + S F+ +E E++ V L + Q + L+ +E + E K T Sbjct: 778 YQILNSSHSSLKENFSI----LETELKNVRDSLDEMTQLRDVLETKDKENQTALLEYKST 833 Query: 1099 KLTFEMNIPKTE-GMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVL 1157 E +I E G+ + + ++D N ++Q EE + L Sbjct: 834 IHKQEDSIKTLEKGLETILSQKKKAEDGIN----KMGKDLFALSREMQAVEENCKN---L 886 Query: 1158 QEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTV 1217 Q++ K N Q+ TK ++ E + ++T +N E + ++K + L+ E +++ + Sbjct: 887 QKEKDKSNVNHQK-ETKSLK-EDIAAKITEIKAIN-ENLEEMKIQCNNLSKEKEHISKEL 943 Query: 1218 AELRSSISS------AVDQRGFEIAELWKQHLAQREA---DFQKTEHELRVQLSAFESKY 1268 E +S S + ++ +A +K A+ E+ +++++E +QLS ++K Sbjct: 944 VEYKSRFQSHDNLVAKLTEKLKSLANNYKDMQAENESLIKAVEESKNESSIQLSNLQNKI 1003 Query: 1269 EQLLDSVQSSTQEETNKIVTMEQVTSLQNKL-QDKEEHLRNLQEKYADVINQIEILRSEI 1327 + + ++ E + +EQ+ + L Q KEE + + +QI +L+ ++ Sbjct: 1004 DSMSQEKENFQIERGSIEKNIEQLKKTISDLEQTKEEIISKSDSSKDEYESQISLLKEKL 1063 Query: 1328 EDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXX 1387 E A +L E +YK ++ + + LK+ Sbjct: 1064 ETATTA-NDENVNKISELTKTREELEAELAAYKNLKNELETKLETSEKALKE-------- 1114 Query: 1388 XXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKR 1447 V + E + E QLE + +E Q+ + L E E++ QL +YE++ Sbjct: 1115 -------VKENEEHLKEEKIQLEKEATETKQQLNSLRANLESLEKEHEDLAAQLKKYEEQ 1167 Query: 1448 IEDLTYEKESELAILRLKMHENANHYETMQK-----ESEIERVKLI--EELNVKITESVS 1500 I + + E++ L ++ E+++K E E++ +K E+ N+K +E + Sbjct: 1168 IANKERQYNEEISQLNDEITSTQQENESIKKKNDELEGEVKAMKSTSEEQSNLKKSEIDA 1227 Query: 1501 LNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLND-------EITNLQNMVRASSSK 1553 LN Q+ EL K E A E ++E++ ++I L D E++ L++ ++AS K Sbjct: 1228 LNLQIKELKKKNETNEASLLESIKSVESETVKIKELQDECNFKEKEVSELEDKLKASEDK 1287 Query: 1554 IQKHVSFASDTKQGRDE 1570 K++ ++++ ++E Sbjct: 1288 NSKYLELQKESEKIKEE 1304 Score = 85.4 bits (202), Expect = 1e-14 Identities = 172/790 (21%), Positives = 348/790 (44%), Gaps = 111/790 (14%) Query: 813 YSEYTIQE-DELVNRLAVLMDHDRVVEKQLLEIEHENKE-LQKKNQILLEENQNLQISLS 870 +S Y IQ +E + R+ + HD E+ + +I E E LQ++ L E +LQ Sbjct: 696 FSTYFIQLFNENIYRIRTALSHDPD-EEPINKISFEEVEKLQRQCTKLKGEITSLQTETE 754 Query: 871 DMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEI 930 H N + T+ + KYQ L S+LK E+ +++ + K + D + Sbjct: 755 ST--HENLTEKLIALTNEHKELDEKYQI-LNSSHSSLK----ENFSILETELKNVRD-SL 806 Query: 931 EFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELID 990 + TQ+ RD VL K ++N + + ++ + + +++I+ L +E + + D Sbjct: 807 DEMTQL----RD--VLETKDKENQTALLEYKSTIHKQEDSIKTLEKGLETILSQKKKAED 860 Query: 991 KHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYES-- 1048 + + E E N N L K+KD+ + ++ + + + +++ ++ Sbjct: 861 GINKMGKDLFALSREMQAVEENCKN-LQKEKDKSNVNHQKETKSLKEDIAAKITEIKAIN 919 Query: 1049 -KLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKEL----KETKLTFE 1103 L + + N+ +E + +SK+L++ K + LV + +++K L K+ + E Sbjct: 920 ENLEEMKIQCNNLSKEKEHISKELVEYKSRFQSHDNLVAKLTEKLKSLANNYKDMQAENE 979 Query: 1104 MNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQ---EQ 1160 I E S+I+ +S+ N +D QE+E F ER ++ EQ Sbjct: 980 SLIKAVEESKNESSIQ-LSNLQNKIDSMS------------QEKENFQIERGSIEKNIEQ 1026 Query: 1161 SAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAEL 1220 K ++L++ +II + + + QI+ LK KLE T ND ++ ++EL Sbjct: 1027 LKKTISDLEQTKEEIISKSDSSKD------EYESQISLLKEKLETATTANDENVNKISEL 1080 Query: 1221 RSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQ 1280 + ++ L A ++ ++EL +L E +++ ++ + + Sbjct: 1081 TKT----------------REELEAELAAYKNLKNELETKLETSEKALKEVKENEEHLKE 1124 Query: 1281 EETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXX 1340 E KI ++ T + +L +L +L++++ D+ Q++ +I +++ Sbjct: 1125 E---KIQLEKEATETKQQLNSLRANLESLEKEHEDLAAQLKKYEEQIANKE--------- 1172 Query: 1341 XXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVND-AE 1399 R N+ Q+ ++ I + +EN +KK + + + Sbjct: 1173 ------------RQYNEEISQLNDE-ITSTQQENESIKKKNDELEGEVKAMKSTSEEQSN 1219 Query: 1400 AKVLELTH-QLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESE 1458 K E+ L++K+ + +T+E ++ + ++ E E V+ K ++D KE E Sbjct: 1220 LKKSEIDALNLQIKELKKKNETNEASLLESIKSVESETVKI------KELQDECNFKEKE 1273 Query: 1459 LAIL--RLKMHENANH-YETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEE 1515 ++ L +LK E+ N Y +QKESE K+ EEL+ K TE +++ L+KA E+ Sbjct: 1274 VSELEDKLKASEDKNSKYLELQKESE----KIKEELDAKTTELKIQLEKITNLSKAKEKS 1329 Query: 1516 VAKTNEM-QTALE---NQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQ 1571 ++ + + +T+ E N E ++ L +EI ++N K+ S S Q E+ Sbjct: 1330 ESELSRLKKTSSEERKNAEEQLEKLKNEI-QIKNQAFEKERKLLNEGS--STITQEYSEK 1386 Query: 1572 LDNTMNKELL 1581 + NT+ EL+ Sbjct: 1387 I-NTLEDELI 1395 >UniRef50_A2ESM9 Cluster: Putative uncharacterized protein; n=1; Trichomonas vaginalis G3|Rep: Putative uncharacterized protein - Trichomonas vaginalis G3 Length = 1105 Score = 138 bits (335), Expect = 9e-31 Identities = 187/976 (19%), Positives = 417/976 (42%), Gaps = 64/976 (6%) Query: 381 KMKSPWSQLSSETLNQDTDKKI-NKNEIAKLEMVIQSLNKDL---VDKEYVISEKDTXXX 436 ++KS + S +N + I K+EI++ + IQ N + + +S+ D Sbjct: 134 QLKSLQDENSQLRVNSISSTSILQKSEISRPQKTIQDFNSPTFLHIFAQVDVSDLDRKLK 193 Query: 437 XXXXXXXGKDTLIAQLQLEHQQHMEG--PSLIHVGTNTEDVNEIAKVQEQLKQEL--NDE 492 L+ LQ +Q+ +I + T +D + V+ +LKQEL N + Sbjct: 194 ALQTDSKTASKLVNSLQKSFKQYTTQMKSKMIEIATQCKD--RVDSVERRLKQELERNSQ 251 Query: 493 IKDVNVKDLIEKLKSAEEQI-TQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVS 551 +K + I L + E+ TQL DE++ + + ++K + L + I + Sbjct: 252 LKHRYDDETIPSLMANHEETETQLRDELNQSMRESDRIKRD----LLDRENAIKTLKR-- 305 Query: 552 DSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAET 611 +++ + E L + + K +EEE L+ ++ + S V K E N A+ Sbjct: 306 -QQRQLFSVCESLKNQNTK---MEEELSQLRSETA-MNASALSTSSV--KYDEAMNEAKR 358 Query: 612 RLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDAL 671 + I+ L+ ++ Q+ D E +LA + + + + +++ I L Sbjct: 359 ANEEINQLQGVLNIAKNKVKKATQRADAAEKELAQLKRNEEE----------MQQSIADL 408 Query: 672 SASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLE--KMSA 729 + S E +++L+ +QL ++ ++L EN + KL ++ A Sbjct: 409 TTSNGEKESKLKDLREANKQLKNKCIQQNEQINELQHELDTIKAENESMQKKLNAAQIEA 468 Query: 730 EKISELLAKINHEEQSKIQTQ---FGIDAKIQERDLYIEN-IESELSKYKSRICRLEESI 785 + + + L +E+S ++ + G AK E+ I N ++ + K + +I LE+ + Sbjct: 469 KNLQQSLTNA-FDEKSVLEEKADSLGTTAKEYEKLKQILNDLKQKKEKAEGQITDLEQKL 527 Query: 786 AVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIE 845 E+ + +L++ + G+ +Q +Q + + DE+ N + ++ ++ +E QL ++ Sbjct: 528 EKSEEEKTALDKTVKEQGNQIQREQAQIKQLIGENDEMQNLIEEKINDNKKLETQLKNLQ 587 Query: 846 HENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLES 905 + +L + L LQ SL D Q + L D + Q ++ + Sbjct: 588 QQLDQLSNEKAELQSNTTILQASLDDKNQKISQLKSDIQEKDAKAFDVQSEQEEMNAKLA 647 Query: 906 NLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQ 965 NL++I +H+ I KK++ D + I +K LNE+ + + + L+ + Q Sbjct: 648 NLEKINDKHKKKIEDLKKQLGD----SSATIVKVENEKNDLNEELGRLKKALESLKQESQ 703 Query: 966 EYKNNIENLNMNVEELNKMNLELIDK--HVQKQQTQSPDYTEQYINEINKLNALLKQKDE 1023 Y++ + L +EE ++ ++ DK ++ K Q ++T + ++L + Q D+ Sbjct: 704 GYQDANKKL---IEENEQLENQIKDKDGNIDKLSRQIQNHTNRISENESQLGEVQSQLDD 760 Query: 1024 EIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQI 1083 + ++ + Q ++ ++ +++ +E + Q ++++L ++K +ELQ Sbjct: 761 AAMTVHSQDQKIQ-QLQRQLAQLTTQKQVSDDRIKELERQNQGIARKLANAK---DELQT 816 Query: 1084 LVREQDDQIKELKETKLTFEMNIPKTEGMII----SSTIEPMSDDANNVDXXXXXXXXXX 1139 + + +++ + E++I EG + TI+ +++ N Sbjct: 817 ALHNNAENEDKIQSQQR--ELDILHKEGESLQKRNQQTIDDLTNQLNKTKEELRQTEQQL 874 Query: 1140 XXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQL 1199 L+ +E + ++ + + ++L+ + QLE + + QI Sbjct: 875 RELQKMKENNDDKMQTAITDLGSELDRTKAKLQATSRQLEQQTKQAQQDKEASDSQIENQ 934 Query: 1200 KSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQ-HLAQREAD-FQKTEHEL 1257 K ++E+LN ++L + + + S+ ++ + ++ +L + +E D QK +L Sbjct: 935 KQEIEKLNQTVNDLTNQINQTNQSLQNSANLYEEQVEQLQNDLNNRNKENDQLQKQTQQL 994 Query: 1258 RVQLSAFESKYEQLLDSVQSSTQEETNKIVTME-QVTSLQNKLQDKEEHL-RNLQEKYAD 1315 + L + + LD+ + ++ T + +E Q+ + KL DK +L + LQ + Sbjct: 995 KDDLIGKIEQLQGDLDAANNKLKDTTQQKGDLEKQMNEEKQKLNDKINNLDQQLQNTQRE 1054 Query: 1316 VINQIEILRSEIEDEK 1331 Q + L +E E K Sbjct: 1055 AQQQAKKLSNENEQLK 1070 Score = 127 bits (307), Expect = 2e-27 Identities = 183/866 (21%), Positives = 369/866 (42%), Gaps = 78/866 (9%) Query: 297 KQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTES 356 KQ +E + + K +++ + E T+ +L + LN +R++++ + L Sbjct: 243 KQELERNSQLKHRYDDETIPSLMANHEETET-QLRDELNQSMRESDRIKRDLL----DRE 297 Query: 357 KAVSSPSKKGSPLISR-KSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQ 415 A+ + ++ L S +S +N +KM+ SQL SET + + + + + Sbjct: 298 NAIKTLKRQQRQLFSVCESLKNQNTKMEEELSQLRSETAMNASALSTSSVKYDEAMNEAK 357 Query: 416 SLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHV--GTNTE 473 N+++ + V++ + +AQL+ ++ + + + G Sbjct: 358 RANEEINQLQGVLNIAKNKVKKATQRADAAEKELAQLKRNEEEMQQSIADLTTSNGEKES 417 Query: 474 DVNEIAKVQEQLKQELNDEIKDVN-VKDLIEKLKSAEEQITQ-LND-EIDAAN-----KN 525 + ++ + +QLK + + + +N ++ ++ +K+ E + + LN +I+A N N Sbjct: 418 KLKDLREANKQLKNKCIQQNEQINELQHELDTIKAENESMQKKLNAAQIEAKNLQQSLTN 477 Query: 526 MIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTE----ELHHLSQKVAELEEEKGNL 581 KS + K + T + K+ ++ + E ++ L QK+ + EEEK L Sbjct: 478 AFDEKSVLEEKADSLGTTAKEYEKLKQILNDLKQKKEKAEGQITDLEQKLEKSEEEKTAL 537 Query: 582 QLHLVDYDSGRMIESDVYKKMI----EMENLAETRLKAISLLESQKFDLVQELHILQQKY 637 + + + E K++I EM+NL E ++ LE+Q +L Q+L L + Sbjct: 538 DKTVKEQGNQIQREQAQIKQLIGENDEMQNLIEEKINDNKKLETQLKNLQQQLDQLSNEK 597 Query: 638 DEVE-----------DKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALV----- 681 E++ DK ISQL+SD + K+ ++ + + ++A L + Sbjct: 598 AELQSNTTILQASLDDKNQKISQLKSDIQEKDAKAFDVQSEQEEMNAKLANLEKINDKHK 657 Query: 682 --IENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKI 739 IE+LK TI +EN+K D+ +L + L K E + ++ L + Sbjct: 658 KKIEDLKKQLGDSSATIVKVENEKNDLNEELGRLKKALESL--KQESQGYQDANKKLIEE 715 Query: 740 NHEEQSKIQTQFG----IDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSL 795 N + +++I+ + G + +IQ I ES+L + +S++ ++ + + L Sbjct: 716 NEQLENQIKDKDGNIDKLSRQIQNHTNRISENESQLGEVQSQLDDAAMTVHSQDQKIQQL 775 Query: 796 ERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKN 855 +R+ QL + Q E Q + +LA D + E E + + Q++ Sbjct: 776 QRQLAQLTTQKQVSDDRIKELERQNQGIARKLANAKDELQTALHNNAENEDKIQSQQREL 835 Query: 856 QILLEENQNLQI----SLSDMQQHYNALVEKANRTD--------LAESESTKYQTQLRDL 903 IL +E ++LQ ++ D+ N E+ +T+ + E+ K QT + DL Sbjct: 836 DILHKEGESLQKRNQQTIDDLTNQLNKTKEELRQTEQQLRELQKMKENNDDKMQTAITDL 895 Query: 904 ESNLKRITH---------EHQTLIVQKKKEIEDLEIEFNTQ----IESAIRD-KKVLNEK 949 S L R E QT Q+ KE D +IE Q + + D +N+ Sbjct: 896 GSELDRTKAKLQATSRQLEQQTKQAQQDKEASDSQIENQKQEIEKLNQTVNDLTNQINQT 955 Query: 950 YEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQK-QQTQSP-DYTEQY 1007 + E Q+++ +N++ N N ++L K +L D + K +Q Q D Sbjct: 956 NQSLQNSANLYEEQVEQLQNDLNNRNKENDQLQKQTQQLKDDLIGKIEQLQGDLDAANNK 1015 Query: 1008 INEINKLNA-LLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQR 1066 + + + L KQ +EE LN KINN + + + + + + + E ++ ++ Sbjct: 1016 LKDTTQQKGDLEKQMNEEKQKLNDKINNLDQQLQNTQREAQQQAKKLSNENEQLKADLDS 1075 Query: 1067 VSKQLLDSKQHNEELQILVREQDDQI 1092 K + +Q N++L + + Q D+I Sbjct: 1076 AKKDIERYEQRNKDL-LQAKGQSDKI 1100 Score = 116 bits (280), Expect = 4e-24 Identities = 187/993 (18%), Positives = 407/993 (40%), Gaps = 58/993 (5%) Query: 500 DLIEKLKSAEEQITQLNDEIDAANKNMIKVKSN-HKLKLKQMQKTIDNFSKVSDSNKEIV 558 D + + S EQ+ L DE N I S K ++ + QKTI +F+ + + + Sbjct: 123 DRLRVIHSLTEQLKSLQDENSQLRVNSISSTSILQKSEISRPQKTIQDFNSPTFLH---I 179 Query: 559 RLTEELHHLSQKVAELE-EEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAIS 617 ++ L +K+ L+ + K +L S + + + KMIE+ + R+ ++ Sbjct: 180 FAQVDVSDLDRKLKALQTDSKTASKLVNSLQKSFKQYTTQMKSKMIEIATQCKDRVDSVE 239 Query: 618 LLESQKFDLVQELHILQQKYDE--VEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASK 675 Q+ + +L + +YD+ + +A+ + ++ Q+ E+ E D + Sbjct: 240 RRLKQELERNSQL---KHRYDDETIPSLMANHEETET-QLRDELNQSMRES--DRIKRDL 293 Query: 676 KELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISEL 735 + I+ LK + QL+ + L+N + +L E L S K E Sbjct: 294 LDRENAIKTLKRQQRQLFSVCESLKNQNTKMEEELSQLRSETAMNASALSTSSV-KYDEA 352 Query: 736 L--AKINHEEQSKIQTQFGIDA-KIQERDLYIENIESELSKYKSRICRLEESIAVMEDRR 792 + AK +EE +++Q I K+++ + E EL++ K +++SIA + Sbjct: 353 MNEAKRANEEINQLQGVLNIAKNKVKKATQRADAAEKELAQLKRNEEEMQQSIADLTTSN 412 Query: 793 YSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQ 852 E K L ++ + + Q +EL + L + + ++K+L + E K LQ Sbjct: 413 GEKESKLKDLREANKQLKNKCIQQNEQINELQHELDTIKAENESMQKKLNAAQIEAKNLQ 472 Query: 853 KKNQILLEENQNLQI---SLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKR 909 + +E L+ SL + Y L + N DL + + K + Q+ DLE L++ Sbjct: 473 QSLTNAFDEKSVLEEKADSLGTTAKEYEKLKQILN--DLKQKKE-KAEGQITDLEQKLEK 529 Query: 910 ITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKN 969 E L K++ ++ E QI+ I + + E+ I +LE QL+ + Sbjct: 530 SEEEKTALDKTVKEQGNQIQRE-QAQIKQLIGENDEMQNLIEEKINDNKKLETQLKNLQQ 588 Query: 970 NIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALN 1029 ++ L+ EL N ++ + + Q + I E + ++ + EE+ A Sbjct: 589 QLDQLSNEKAELQS-NTTILQASLD-DKNQKISQLKSDIQEKDAKAFDVQSEQEEMNAKL 646 Query: 1030 QKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQD 1089 + + + D + +L + + +E E ++++L K+ E L+ + Sbjct: 647 ANLEKINDKHKKKIEDLKKQLGDSSATIVKVENEKNDLNEELGRLKKALESLKQESQGYQ 706 Query: 1090 DQIKELKETKLTFEMNIPKTEGMI--ISSTIEPMSD--DANNVDXXXXXXXXXXXXLKVQ 1145 D K+L E E I +G I +S I+ ++ N + V Sbjct: 707 DANKKLIEENEQLENQIKDKDGNIDKLSRQIQNHTNRISENESQLGEVQSQLDDAAMTVH 766 Query: 1146 EEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTG--------------HDVV 1191 +++ IQ+ LQ Q A+L T+ Q +I +LE N + ++ Sbjct: 767 SQDQKIQQ---LQRQLAQLTTQKQVSDDRIKELERQNQGIARKLANAKDELQTALHNNAE 823 Query: 1192 NQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQ 1251 N+++I + +L+ L+ E ++L + +++ +++ E+ + +Q L + + + Sbjct: 824 NEDKIQSQQRELDILHKEGESLQKRNQQTIDDLTNQLNKTKEELRQT-EQQLRELQKMKE 882 Query: 1252 KTEHELRVQLSAFESKYEQLLDSVQSSTQ--EETNKIVTMEQVTSLQNKLQDKEEHLRNL 1309 + +++ ++ S+ ++ +Q++++ E+ K ++ S ++++++++ + L Sbjct: 883 NNDDKMQTAITDLGSELDRTKAKLQATSRQLEQQTKQAQQDKEAS-DSQIENQKQEIEKL 941 Query: 1310 QEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXD---LRTENQSYKQ----M 1362 + D+ NQI +++ + + L+ + Q K Sbjct: 942 NQTVNDLTNQINQTNQSLQNSANLYEEQVEQLQNDLNNRNKENDQLQKQTQQLKDDLIGK 1001 Query: 1363 QEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHE 1422 EQ +++ N +LK ++ K+ L QL+ E Q+ + Sbjct: 1002 IEQLQGDLDAANNKLKDTTQQKGDLEKQMNEEKQKLNDKINNLDQQLQNTQREAQQQAKK 1061 Query: 1423 YTITLTQRNDEFENVRQQLVEYEKRIEDLTYEK 1455 + Q + ++ ++ + YE+R +DL K Sbjct: 1062 LSNENEQLKADLDSAKKDIERYEQRNKDLLQAK 1094 Score = 107 bits (256), Expect = 3e-21 Identities = 176/996 (17%), Positives = 414/996 (41%), Gaps = 63/996 (6%) Query: 634 QQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLY 693 ++K ++ I + SD + ++ L+EQI + S++ L+ + L +EQ Sbjct: 26 ERKKSFIKSLQDSIKSISSDLIVRQL----LQEQISSNYLSQRIDELISKMLNDGREQFI 81 Query: 694 GTIKDLENDKEDIMNKLQNYIQENM-----DLTDKLEKMSAEKISELLA-----KINHEE 743 T+ N E I N + + M D SA+++ + + K +E Sbjct: 82 DTLIQKINKYEAIFNDERTELLRVMGDRVLSFADSQITTSADRLRVIHSLTEQLKSLQDE 141 Query: 744 QSKIQTQFGIDAKIQERDLYIENIESELSKYKS-RICRLEESIAVME-DRRY-SLERKAD 800 S+++ I ++ I + + + S + + V + DR+ +L+ + Sbjct: 142 NSQLRVNSISSTSILQKS-EISRPQKTIQDFNSPTFLHIFAQVDVSDLDRKLKALQTDSK 200 Query: 801 QLGSYLQEKQKAYSEYTIQ-EDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKK--NQI 857 + QK++ +YT Q + +++ D VE++L + N +L+ + ++ Sbjct: 201 TASKLVNSLQKSFKQYTTQMKSKMIEIATQCKDRVDSVERRLKQELERNSQLKHRYDDET 260 Query: 858 LLEENQNLQISLSDMQQHYNALVEKANRT--DLAESEST--KYQTQLRDLESNLKRITHE 913 + N + + + ++ N + +++R DL + E+ + Q R L S + + ++ Sbjct: 261 IPSLMANHEETETQLRDELNQSMRESDRIKRDLLDRENAIKTLKRQQRQLFSVCESLKNQ 320 Query: 914 HQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIEN 973 + + + + + + + S+++ + +NE N E + QL+ L KN ++ Sbjct: 321 NTKMEEELSQLRSETAMNASALSTSSVKYDEAMNEAKRAN-EEINQLQGVLNIAKNKVKK 379 Query: 974 LNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALL---KQKDEEIIALNQ 1030 + K L + ++ ++ Q D T + +KL L KQ + I N+ Sbjct: 380 ATQRADAAEK-ELAQLKRNEEEMQQSIADLTTSNGEKESKLKDLREANKQLKNKCIQQNE 438 Query: 1031 KINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDD 1090 +IN Q ++ ++ ES + + + +Q+ D K EE + Sbjct: 439 QINELQHELDTIKAENESMQKKLNAA-QIEAKNLQQSLTNAFDEKSVLEEKADSLGTTAK 497 Query: 1091 QIKELKETKLTFEMNIPKTEGMI--ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEE 1148 + ++LK+ + K EG I + +E ++ +D + Q ++ Sbjct: 498 EYEKLKQILNDLKQKKEKAEGQITDLEQKLEKSEEEKTALDKTVKEQGNQIQREQAQIKQ 557 Query: 1149 ---EFIQERSVLQEQ---SAKLNTELQECYTKIIQLETLNTELTGHDVVNQ-------EQ 1195 E + +++++E+ + KL T+L+ ++ QL EL + + Q ++ Sbjct: 558 LIGENDEMQNLIEEKINDNKKLETQLKNLQQQLDQLSNEKAELQSNTTILQASLDDKNQK 617 Query: 1196 INQLKSKLEQLNTENDNLLSTVAELRSSISSAV---DQRGFEIAELWKQHLAQREADFQK 1252 I+QLKS +++ + + ++ S E+ + +++ D+ +I +L KQ L A K Sbjct: 618 ISQLKSDIQEKDAKAFDVQSEQEEMNAKLANLEKINDKHKKKIEDLKKQ-LGDSSATIVK 676 Query: 1253 TEHELRVQLSAFESKYEQLLDSVQSSTQ--EETNKIVTMEQVTSLQNKLQDKEEHLRNLQ 1310 E+E + L+ + ++ L+S++ +Q ++ NK + +E+ L+N+++DK+ ++ L Sbjct: 677 VENE-KNDLNEELGRLKKALESLKQESQGYQDANKKL-IEENEQLENQIKDKDGNIDKLS 734 Query: 1311 EKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQ--SYKQMQEQSIL 1368 + + N+I S++ + + R Q + KQ+ + I Sbjct: 735 RQIQNHTNRISENESQLGEVQSQLDDAAMTVHSQDQKIQQLQRQLAQLTTQKQVSDDRIK 794 Query: 1369 NINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLEL--KDSEIYQKTHEYTIT 1426 + +N + + + E K+ +L++ K+ E QK ++ TI Sbjct: 795 ELERQNQGIARKLANAKDELQTALHNNAENEDKIQSQQRELDILHKEGESLQKRNQQTID 854 Query: 1427 -----LTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESE 1481 L + +E QQL E +K E+ + ++ + L ++ + ++ E Sbjct: 855 DLTNQLNKTKEELRQTEQQLRELQKMKENNDDKMQTAITDLGSELDRTKAKLQATSRQLE 914 Query: 1482 IERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEIT 1541 + + ++ ++ + +++ +LN+ + + + N+ +L+N +++ Sbjct: 915 QQTKQAQQDKEASDSQIENQKQEIEKLNQTVNDLTNQINQTNQSLQNSANLYEEQVEQLQ 974 Query: 1542 NLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMN 1577 N N + ++QK D G+ EQL ++ Sbjct: 975 NDLNNRNKENDQLQKQTQQLKDDLIGKIEQLQGDLD 1010 Score = 99.1 bits (236), Expect = 9e-19 Identities = 175/908 (19%), Positives = 373/908 (41%), Gaps = 80/908 (8%) Query: 55 ERAQKCLENAALVSKRIKEHRKATAELLGRPFVPGISESLANTLKQKEILMEKIKQYKEL 114 E A +C + V +R+K+ + ++L R I +AN + + L +++ Q Sbjct: 226 EIATQCKDRVDSVERRLKQELERNSQLKHRYDDETIPSLMANHEETETQLRDELNQSMRE 285 Query: 115 SKRSSTTIV-RXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKD--NALSVLQVKMKIMETT 171 S R ++ R + + NT E++ S + + T+ Sbjct: 286 SDRIKRDLLDRENAIKTLKRQQRQLFSVCESLKNQNTKMEEELSQLRSETAMNASALSTS 345 Query: 172 ILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAE 231 + E +NE + E N+ + ++++ +++ N E E Sbjct: 346 SVKYDEAMNEAKRANEEINQ-LQGVLNIAKNKVKKATQRADAAEKELAQLKRN----EEE 400 Query: 232 WKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELE------QXXXXX 285 + L K+ ++ L EANK L+ + + + ++L EL+ + Sbjct: 401 MQQSIADLTTSNGEKESKLKDLREANKQLKNKCIQQNEQINELQHELDTIKAENESMQKK 460 Query: 286 XXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKEL 345 +QS+ + +EK+ +EEK ++ K+ E L+ + ++Q ++ Sbjct: 461 LNAAQIEAKNLQQSLTNAFDEKSVLEEKAD----SLGTTAKEYEKLKQILNDLKQKKEKA 516 Query: 346 ENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSET--LNQDTDKKIN 403 E ++ + E K S +K + + K N + ++ QL E + ++KIN Sbjct: 517 EGQITDL--EQKLEKSEEEKTALDKTVKEQGNQIQREQAQIKQLIGENDEMQNLIEEKIN 574 Query: 404 KNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQ----- 458 N+ KLE +++L + L +E + K+ I+QL+ + Q+ Sbjct: 575 DNK--KLETQLKNLQQQLDQLSNEKAELQSNTTILQASLDDKNQKISQLKSDIQEKDAKA 632 Query: 459 ---HMEGPSLIHVGTNTEDVNEIAKVQ-EQLKQELNDE----IKDVNVK-DLIE---KLK 506 E + N E +N+ K + E LK++L D +K N K DL E +LK Sbjct: 633 FDVQSEQEEMNAKLANLEKINDKHKKKIEDLKKQLGDSSATIVKVENEKNDLNEELGRLK 692 Query: 507 SAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFS--------KVSDSNKEIV 558 A E + Q + ANK +I+ + ++K ID S ++S++ ++ Sbjct: 693 KALESLKQESQGYQDANKKLIEENEQLENQIKDKDGNIDKLSRQIQNHTNRISENESQLG 752 Query: 559 RLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISL 618 + +L + V +++ LQ L + + + D K+ +E +N R Sbjct: 753 EVQSQLDDAAMTVHSQDQKIQQLQRQLAQLTTQKQVSDDRIKE-LERQNQGIAR-----K 806 Query: 619 LESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKEL 678 L + K +L LH + D+++ + ++ L + E ++ ID L+ +L Sbjct: 807 LANAKDELQTALHNNAENEDKIQSQQRELDILHKE---GESLQKRNQQTIDDLT---NQL 860 Query: 679 ALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAK 738 E L+ ++QL ++L+ KE+ +K+Q I DL +L++ A K+ + Sbjct: 861 NKTKEELRQTEQQL----RELQKMKENNDDKMQTAI---TDLGSELDRTKA-KLQATSRQ 912 Query: 739 INHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERK 798 + + + Q + D++I+ + IE + ++ ++I + +S +++ E + Sbjct: 913 LEQQTKQAQQDKEASDSQIENQKQEIEKLNQTVNDLTNQINQTNQS---LQNSANLYEEQ 969 Query: 799 ADQLGSYLQEKQKAYSEYTIQ----EDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKK 854 +QL + L + K + Q +D+L+ ++ L +L + + +L+K+ Sbjct: 970 VEQLQNDLNNRNKENDQLQKQTQQLKDDLIGKIEQLQGDLDAANNKLKDTTQQKGDLEKQ 1029 Query: 855 NQILLEENQNLQISLSDM-QQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHE 913 + EE Q L ++++ QQ N E + +E+ + + L + +++R Sbjct: 1030 ---MNEEKQKLNDKINNLDQQLQNTQREAQQQAKKLSNENEQLKADLDSAKKDIERYEQR 1086 Query: 914 HQTLIVQK 921 ++ L+ K Sbjct: 1087 NKDLLQAK 1094 Score = 93.5 bits (222), Expect = 4e-17 Identities = 164/838 (19%), Positives = 354/838 (42%), Gaps = 84/838 (10%) Query: 212 EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271 E K Q TKM+E + +E L D ++ + AN+ + + +++ Sbjct: 315 ESLKNQNTKMEEELSQLRSETAMNASALSTSSVKYDEAMNEAKRANEEINQLQGVLNIAK 374 Query: 272 SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELL 331 +K+ + ++ ++ ++ S + T + ++ ++ E K+ L Sbjct: 375 NKVKKATQRADAAEKELAQLKRN--EEEMQQSIADLTTSNGEKESKLKDLREANKQ---L 429 Query: 332 EHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSS 391 ++ Q + EL+++L T+ E++ S K + I K+ + + + S L Sbjct: 430 KNKCIQQNEQINELQHELDTIKAENE--SMQKKLNAAQIEAKNLQQSLTNAFDEKSVLEE 487 Query: 392 ETLNQDTDKKINKNEIAKLEMVIQSLNK-------DLVDKEYVI--SEKDTXXXXXXXXX 442 + + T K E KL+ ++ L + + D E + SE++ Sbjct: 488 KADSLGTTAK----EYEKLKQILNDLKQKKEKAEGQITDLEQKLEKSEEEKTALDKTVKE 543 Query: 443 XGKDTLIAQLQLEH--QQHMEGPSLIH--VGTNTEDVNEIAKVQEQLKQELNDEIK-DVN 497 G Q Q++ ++ E +LI + N + ++ +Q+QL Q N++ + N Sbjct: 544 QGNQIQREQAQIKQLIGENDEMQNLIEEKINDNKKLETQLKNLQQQLDQLSNEKAELQSN 603 Query: 498 VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSN-KE 556 L L ++I+QL +I + V+S ++M + N K++D + K+ Sbjct: 604 TTILQASLDDKNQKISQLKSDIQEKDAKAFDVQSEQ----EEMNAKLANLEKINDKHKKK 659 Query: 557 IVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAI 616 I L ++L S + ++E EK +L L GR+ KK +E + ++ Sbjct: 660 IEDLKKQLGDSSATIVKVENEKNDLNEEL-----GRL------KKALE-----SLKQESQ 703 Query: 617 SLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSV-HLEEQIDALSASK 675 ++ K L++E +Q ++++DK +I +L S Q+ + + E Q+ + + Sbjct: 704 GYQDANK-KLIEE---NEQLENQIKDKDGNIDKL-SRQIQNHTNRISENESQLGEVQSQL 758 Query: 676 KELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISEL 735 + A+ + + +QL + L K+ ++++ ++N + KL E + L Sbjct: 759 DDAAMTVHSQDQKIQQLQRQLAQLTTQKQVSDDRIKELERQNQGIARKLANAKDELQTAL 818 Query: 736 LAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSL 795 N E + KIQ+ Q+R+L I + E E S K R +++I + ++ Sbjct: 819 --HNNAENEDKIQS--------QQRELDILHKEGE-SLQK----RNQQTIDDLTNQLNKT 863 Query: 796 ERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRV-VEKQLLEIEHENKELQKK 854 + + Q L+E QK + + L +D + ++ ++E + K+ Q+ Sbjct: 864 KEELRQTEQQLRELQKMKENNDDKMQTAITDLGSELDRTKAKLQATSRQLEQQTKQAQQD 923 Query: 855 NQILLEENQNLQISLSDMQQHYNALVEKANRTDLA-ESESTKYQTQLRDLESNLKRITHE 913 + + +N + + + Q N L + N+T+ + ++ + Y+ Q+ L+++L E Sbjct: 924 KEASDSQIENQKQEIEKLNQTVNDLTNQINQTNQSLQNSANLYEEQVEQLQNDLNNRNKE 983 Query: 914 HQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIEN 973 + Q +K+ + L+ + +IE D N K + + LE Q+ E K + Sbjct: 984 ND----QLQKQTQQLKDDLIGKIEQLQGDLDAANNKLKDTTQQKGDLEKQMNEEK---QK 1036 Query: 974 LNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQK 1031 LN +++N +D+ +Q Q ++ ++ NE +L A L ++I Q+ Sbjct: 1037 LN---DKINN-----LDQQLQNTQREAQQQAKKLSNENEQLKADLDSAKKDIERYEQR 1086 >UniRef50_UPI0000F1FE72 Cluster: PREDICTED: hypothetical protein; n=2; Danio rerio|Rep: PREDICTED: hypothetical protein - Danio rerio Length = 1889 Score = 138 bits (334), Expect = 1e-30 Identities = 246/1246 (19%), Positives = 531/1246 (42%), Gaps = 127/1246 (10%) Query: 387 SQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKD 446 +Q++S Q D + ++ I L ++ L+ E + EK+ D Sbjct: 446 AQVASLRSQQIKDAEKHQLVITNLNKQLKGLSSTQECLESSLMEKEHTLARTSEKLECID 505 Query: 447 TLIAQLQLEHQQHME-GPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVK-----D 500 +L L+ + +Q+ + L+ N +V + E+ E+ + ++ +K D Sbjct: 506 SLREALEAKEKQNQDQADRLLQSEHNLAEVKKTCSNFEKENSEMKAAVAELTLKLGVMKD 565 Query: 501 LIEK----LKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKV-SDSNK 555 +K ++S + + Q NDE+D N ++ ++ L+ ++ ID V +D +K Sbjct: 566 KSQKQDTAIESLQSDLVQTNDELDRLNTVHLEERAQLVHDLQSCEREIDRLQDVITDKDK 625 Query: 556 EIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKA 615 EI+ L+ + S+++ EL++E ++ DV K+ EN+ R Sbjct: 626 EILALSSSMAEYSEQIHELKQEM--------------KLKEDVLTKV--EENVQIFRDPQ 669 Query: 616 ISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASK 675 +S + Q F+++ I Q K E + K+A + +S+ +EIK + + D K Sbjct: 670 LS--DQQFFNILIPKLIEQLKKTESDLKVA---KKESESRSNEIKDFIKQTEDD-----K 719 Query: 676 KELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISEL 735 K +I++L+++ ++L +K+ ++D E + K ++++E + L ++S +K L Sbjct: 720 K----IIQDLRMEIQKLQINLKEPQSDGEQVHEK--DFLKEERNKL--LSEVSKQKSELL 771 Query: 736 LAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRIC----RLEESIAVMEDR 791 EEQ Q Q D IQ++ I ++E +L + + R + + ++ Sbjct: 772 RFSKTIEEQVACQEQLKQD--IQDKSEVIFSLEQKLKIVQEELVVERDRFNSELTIRDEA 829 Query: 792 RYSLER----KADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHE 847 + LE+ + D + S + QK EL ++ +L +E Q L+ ++ Sbjct: 830 KEHLEKSLSCEIDSVKSVKNDNQKLKESLEQNLGELASQKQLL--DSAAIEIQALQDQNS 887 Query: 848 N-----KELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTK----YQT 898 + K L+ N L E + SLSD+ + L+ K ++ +L SES K +Q Sbjct: 888 SLIFQVKSLESDNCHLRVEIETRVQSLSDVSEEKKRLLNKISQIELQLSESVKTISDFQR 947 Query: 899 QLRDL---ESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNI- 954 +L E++LK+ +++ I + E + + N I+ + +++L+EK ++ + Sbjct: 948 DKEELYLREADLKKELEKNKQSITEISLEKDGVVELHNALIKQNQQLQEILDEKQKEALV 1007 Query: 955 --EYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEIN 1012 + V+ L ++ E L + L++ N L + + +Q + T++ N Sbjct: 1008 LTQAVSDLNNKITITLKENEKLASQIVSLDEQNGSL-QRQINEQMKSLTETTKERETLQN 1066 Query: 1013 KLNALLKQKDEEIIALNQKINNAQVSYMSMVSDY---ESKLAQFTTKLENMEEEMQRVSK 1069 K+ + +D E + + + A+ + V ++ E KL L+ E +++ Sbjct: 1067 KIQ-FFETQDVENHKIIEGLLKAKEDLLLQVEEHKVIEQKLQANAEMLQKKSSECTDLTQ 1125 Query: 1070 QLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVD 1129 L ++K+ + L+ + + ++ + K L E I + M I + + +N+ Sbjct: 1126 GLSETKEEVDHLKRKLESSNSEVVKCKNIMLEKE-KILTDQRMQIEAYQQQFKHLQDNIS 1184 Query: 1130 XXXXXXXXXXXXLKVQEEEEFIQERS----VLQEQSAK----LNTELQECYTKIIQLETL 1181 L E++ +Q+ S +LQ++ + T QE + ++ L Sbjct: 1185 VLQEQAFKHKSGLT--EKDTLLQKESNACVLLQKELGHERELVFTSQQEISSLKVECSRL 1242 Query: 1182 NTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAEL---RSSISSAVDQRGFEIAEL 1238 N L + +E+ + ++ LE+L N+ L+S ++L +SI+ ++ + + Sbjct: 1243 NQALEEKENTLREKNLECQNHLEELCKRNETLVSLTSQLGLMNASIAK-LESDNANLKDT 1301 Query: 1239 WKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTM----EQVTS 1294 ++HL++ A ++ + +++L ++ + + D E N + M E +TS Sbjct: 1302 LERHLSE-SARLKEELMQKQIELVEYQDSGQAMNDQNSIIKSELKNSMTEMVRQKEMITS 1360 Query: 1295 LQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXD--- 1351 LQN+L+ K L +L+EK+ +Q+E L+ + D++ F Sbjct: 1361 LQNELESKRVKLGSLEEKFKSEHSQLEALQLTLRDKEDVFQTQEMHVNNMQAKLLESEGQ 1420 Query: 1352 -------LRTENQSYKQMQEQSILNINEENAQLKKSSXXXXX-------XXXXXXXRVND 1397 L+ ENQS + E + L S + + Sbjct: 1421 IKQRILKLQEENQSLRTALEDKDKEFSLVKTTLLAQSEACESRLKSEMVATAQFQREIQN 1480 Query: 1398 AEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQ------QLVEYEKRIEDL 1451 + K+ +L + KDS + Q+ +Y + ++ V Q QL K++ + Sbjct: 1481 LQEKMNQLISIITEKDSLLMQEKEKYMCLQSSASELESTVSQLNCQIKQLTSEIKQLRET 1540 Query: 1452 TYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKA 1511 +KE + +M + Y+ +Q+E ++ + +L++ LN K + + K + E Sbjct: 1541 QTKKEQVTFAAQSQMQKLDELYKNLQQECDLTKQELLKVLNEKSLKEEEVRKLILE---- 1596 Query: 1512 LEEEVAKTN--EMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQ 1555 +E++ +T+ ++QT + Q T +++ +Q M + K++ Sbjct: 1597 -KEDILRTSSYQIQTTQDQQHNWRSTTMNKVEEVQAMEKKKLHKME 1641 Score = 117 bits (281), Expect = 3e-24 Identities = 226/1176 (19%), Positives = 483/1176 (41%), Gaps = 101/1176 (8%) Query: 477 EIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLN--DEIDAANKNMIKVKSNHK 534 E+ KVQ + ++ ++ ++ + + E + EE +++L +++ A N+ + K +K Sbjct: 194 ELKKVQSGICVNMSPDVTSLHSR-ITELQEEREEMLSKLELYEDMKAKNEELRKQLMEYK 252 Query: 535 LKLKQMQKTIDNFSKVSDSNKEIVRLTE-ELHHLSQKVAELEE-EKGNLQLHLVDYDSGR 592 + +MQ ++ +K + S + + ++ + V + E E+G Q H + + R Sbjct: 253 EQQSKMQADLEQVTKRASSQASETGMDDVQVMEWQEMVTMVTEAERGRDQGHEKNVMAFR 312 Query: 593 MIESDVYKKMI-EMENLAETRLKAISLLESQKFDLVQEL--HILQQKYDEVEDKLADISQ 649 M + ++ + + E L + L QK + LQ+++ +D + D+ Sbjct: 313 MSHIEEEREALANRQQEVEEELAQVHGLCPQKSRKPKYFTPRSLQEEFHNTQDPMGDMDH 372 Query: 650 LQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNK 709 D + + Q A A L V+E L+L++ QL I LE +D+ ++ Sbjct: 373 ---DGLINGENMGGWWPQHSA--ADTDGLRSVVEELELERNQLQEQILVLEKQCQDLEDR 427 Query: 710 LQNYIQENMDLTD-KLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIE 768 LQ +Q ++L + E++ A+ S +I E+ ++ ++ +++ E +E Sbjct: 428 LQ--LQARIELLQHESERLQAQVASLRSQQIKDAEKHQLVIT-NLNKQLKGLSSTQECLE 484 Query: 769 SELSKYKSRICRLEESIAVMEDRRYSLERKA----DQLGSYLQEK-------------QK 811 S L + + + R E + ++ R +LE K DQ LQ + +K Sbjct: 485 SSLMEKEHTLARTSEKLECIDSLREALEAKEKQNQDQADRLLQSEHNLAEVKKTCSNFEK 544 Query: 812 AYSEYTIQEDELVNRLAVLMD----HDRVVEKQLLEIEHENKELQKKNQILLEENQNLQI 867 SE EL +L V+ D D +E ++ N EL + N + LEE L Sbjct: 545 ENSEMKAAVAELTLKLGVMKDKSQKQDTAIESLQSDLVQTNDELDRLNTVHLEERAQLVH 604 Query: 868 SLSDMQQHYNALVEKANRTD---LAESES-TKYQTQLRDLESNLKR----ITHEHQTLIV 919 L ++ + L + D LA S S +Y Q+ +L+ +K +T + + + Sbjct: 605 DLQSCEREIDRLQDVITDKDKEILALSSSMAEYSEQIHELKQEMKLKEDVLTKVEENVQI 664 Query: 920 QKKKEIEDLEIEFNTQIESAIR-------DKKVLNEKYEKNIEYVTQLEAQLQEYKNNIE 972 + ++ D + FN I I D KV ++ E + Q ++ K I+ Sbjct: 665 FRDPQLSDQQF-FNILIPKLIEQLKKTESDLKVAKKESESRSNEIKDFIKQTEDDKKIIQ 723 Query: 973 NLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKI 1032 +L M E+ K+ + L + +Q D+ ++ E NKL + + ++ E++ ++ I Sbjct: 724 DLRM---EIQKLQINLKEPQSDGEQVHEKDFLKE---ERNKLLSEVSKQKSELLRFSKTI 777 Query: 1033 NNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLL-DSKQHNEELQILVREQDDQ 1091 + D + K + + ++E++++ V ++L+ + + N EL I D+ Sbjct: 778 EEQVACQEQLKQDIQDK----SEVIFSLEQKLKIVQEELVVERDRFNSELTIR-----DE 828 Query: 1092 IKELKETKLTFEMNIPKT---EGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEE 1148 KE E L+ E++ K+ + + ++E + + L+ Q Sbjct: 829 AKEHLEKSLSCEIDSVKSVKNDNQKLKESLEQNLGELASQKQLLDSAAIEIQALQDQNSS 888 Query: 1149 EFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNT 1208 Q +S L+ + L E++ + + L + Q+++ + Sbjct: 889 LIFQVKS-LESDNCHLRVEIETRVQSLSDVSEEKKRLLNKISQIELQLSESVKTISDFQR 947 Query: 1209 ENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKY 1268 + + L A+L+ + +++ L K + + K +L+ L E + Sbjct: 948 DKEELYLREADLKKELEK--NKQSITEISLEKDGVVELHNALIKQNQQLQEILD--EKQK 1003 Query: 1269 EQLLDSVQSSTQEETNKI-VTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEI 1327 E L+ + + + NKI +T+++ L +++ +E +LQ + + + + E Sbjct: 1004 EALV--LTQAVSDLNNKITITLKENEKLASQIVSLDEQNGSLQRQINEQMKSLTETTKER 1061 Query: 1328 EDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNIN-EENAQL--KKSSXXX 1384 E + L+ + Q++E ++ + NA++ KKSS Sbjct: 1062 ETLQNKIQFFETQDVENHKIIEGLLKAKEDLLLQVEEHKVIEQKLQANAEMLQKKSSECT 1121 Query: 1385 XXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTH---EYTITLTQRNDEFENVRQQL 1441 +++ + +V L +LE +SE+ + + E LT + + E +QQ Sbjct: 1122 DLTQG-----LSETKEEVDHLKRKLESSNSEVVKCKNIMLEKEKILTDQRMQIEAYQQQF 1176 Query: 1442 VEYEKRI---EDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITES 1498 + I ++ ++ +S L + + +N +QKE ER E + E Sbjct: 1177 KHLQDNISVLQEQAFKHKSGLTEKDTLLQKESNACVLLQKELGHER----ELVFTSQQEI 1232 Query: 1499 VSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHV 1558 SL + + LN+ALEE+ E +N E+ N+ + +L + + ++ I K Sbjct: 1233 SSLKVECSRLNQALEEKENTLREKNLECQNHLEELCKRNETLVSLTSQLGLMNASIAKLE 1292 Query: 1559 SFASDTKQGRDEQLDNTMNKELLDAVPRAELDLAMY 1594 S ++ K + L + L + + + +++L Y Sbjct: 1293 SDNANLKDTLERHLSE--SARLKEELMQKQIELVEY 1326 Score = 99.1 bits (236), Expect = 9e-19 Identities = 218/1069 (20%), Positives = 435/1069 (40%), Gaps = 83/1069 (7%) Query: 147 LSNTIKEKDNAL---SVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXX 203 LS K+K L ++ ++ E D+Q+K +E +E K K Sbjct: 760 LSEVSKQKSELLRFSKTIEEQVACQEQLKQDIQDK-SEVIFSLEQKLKIVQEELVVERDR 818 Query: 204 XXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAA 263 ++ K+ + K I K++ Q+L + +E + L +LL++A Sbjct: 819 FNSELTIRDEAKEHLEKSLSCEIDSVKSVKNDNQKLKESLEQN---LGELASQKQLLDSA 875 Query: 264 RFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAK--QSIEPSCEEKTEIEEKGSLEIANM 321 EI + + + Q + QS+ EEK + K S + Sbjct: 876 AIEIQALQDQNSSLIFQVKSLESDNCHLRVEIETRVQSLSDVSEEKKRLLNKISQIELQL 935 Query: 322 TELTKKIELL----EHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRN 377 +E K I E L + KELE ++ S + + LI + Sbjct: 936 SESVKTISDFQRDKEELYLREADLKKELEKNKQSITEISLEKDGVVELHNALIKQNQQLQ 995 Query: 378 TASKMKSPWSQLSSETLNQDTDK-KINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXX 436 K + + ++ ++ +K I E KL I SL++ + I+E+ Sbjct: 996 EILDEKQKEALVLTQAVSDLNNKITITLKENEKLASQIVSLDEQNGSLQRQINEQ---MK 1052 Query: 437 XXXXXXXGKDTLIAQLQLEHQQHMEGPSLIH-VGTNTEDVN---EIAKVQEQLKQELNDE 492 ++TL ++Q Q +E +I + ED+ E KV EQ K + N E Sbjct: 1053 SLTETTKERETLQNKIQFFETQDVENHKIIEGLLKAKEDLLLQVEEHKVIEQ-KLQANAE 1111 Query: 493 I---KDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSK 549 + K DL + L +E++ L +++++N ++K K N L+ +++ Sbjct: 1112 MLQKKSSECTDLTQGLSETKEEVDHLKRKLESSNSEVVKCK-NIMLEKEKI--------- 1161 Query: 550 VSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESD----VYKKMIEM 605 ++D +I ++ HL ++ L+E+ + L + D+ ES+ + K++ Sbjct: 1162 LTDQRMQIEAYQQQFKHLQDNISVLQEQAFKHKSGLTEKDTLLQKESNACVLLQKELGHE 1221 Query: 606 ENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKS-VHL 664 L T + IS L+ + L Q L ++K + + +K + Q +++C ++ V L Sbjct: 1222 RELVFTSQQEISSLKVECSRLNQAL---EEKENTLREKNLEC-QNHLEELCKRNETLVSL 1277 Query: 665 EEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKL 724 Q+ ++AS +L NLK + L + + KE++M K Q + E D + Sbjct: 1278 TSQLGLMNASIAKLESDNANLK---DTLERHLSESARLKEELMQK-QIELVEYQDSGQAM 1333 Query: 725 EKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEES 784 ++ SEL + + K + + +++ + + + ++E + S++ L+ + Sbjct: 1334 NDQNSIIKSELKNSMTEMVRQK-EMITSLQNELESKRVKLGSLEEKFKSEHSQLEALQLT 1392 Query: 785 IAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQ-EDELVNRLAVLMDHDRVVE--KQL 841 + ED + E + + + L E + + ++ ++E + L D D+ K Sbjct: 1393 LRDKEDVFQTQEMHVNNMQAKLLESEGQIKQRILKLQEENQSLRTALEDKDKEFSLVKTT 1452 Query: 842 LEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTD-LAESESTKY---Q 897 L + E E + K++++ Q + ++Q+ N L+ D L E KY Q Sbjct: 1453 LLAQSEACESRLKSEMVA--TAQFQREIQNLQEKMNQLISIITEKDSLLMQEKEKYMCLQ 1510 Query: 898 TQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYV 957 + +LES + ++ + + L + K++ + + + +A + L+E Y KN++ Sbjct: 1511 SSASELESTVSQLNCQIKQL-TSEIKQLRETQTKKEQVTFAAQSQMQKLDELY-KNLQQE 1568 Query: 958 TQLEAQLQEYKNNIENLNMNVEELNKMNLELID------KHVQKQQTQSPDYTEQYINEI 1011 L Q E + ++ EE+ K+ LE D +Q Q Q ++ +N++ Sbjct: 1569 CDLTKQ--ELLKVLNEKSLKEEEVRKLILEKEDILRTSSYQIQTTQDQQHNWRSTTMNKV 1626 Query: 1012 NKLNALLKQK--DEEIIALNQK---------INNAQVSYMSMVSDYESKLAQFTTKLENM 1060 ++ A+ K+K E +AL K +N + E L Q KL+ Sbjct: 1627 EEVQAMEKKKLHKMEFMALQGKEASSDQWVQLNGHLQQCQLEIQQRECGLQQLNIKLQQT 1686 Query: 1061 EEEMQRVSKQLLDSKQHNEELQILVREQDDQIK-ELKETKLTFEMNIPK-TEGMIISSTI 1118 EE + VS+ L D++Q ELQ + Q++ +L T+ + +P ISST+ Sbjct: 1687 IEEKEGVSRMLKDTQQSVSELQNRCYWLERQVQNQLSPTQGSVYGEVPPGAPQEPISSTV 1746 Query: 1119 EPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTE 1167 + D+ ++ L + EEE + R + E++ +L + Sbjct: 1747 NQVGSDSRDLRMRLSEAEIHLSQLNSRLEEE--RSRREVAEEALRLTEQ 1793 Score = 83.4 bits (197), Expect = 5e-14 Identities = 207/1133 (18%), Positives = 463/1133 (40%), Gaps = 98/1133 (8%) Query: 143 DVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXX 202 ++ L + I +KD + L M I +L++++ K+ ++ + Sbjct: 612 EIDRLQDVITDKDKEILALSSSMAEYSEQIHELKQEMKLKEDVLTKVEENVQIFRDPQLS 671 Query: 203 XXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEA 262 +Q+ K + + + E + + I+ + +++ +E Sbjct: 672 DQQFFNILIPKLIEQLKKTESDLKVAKKESESRSNEIKDFIKQTEDDKKIIQDLR--MEI 729 Query: 263 ARFEISLEHSKL-AQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANM 321 + +I+L+ + +++ + ++KQ E KT IEE+ + + Sbjct: 730 QKLQINLKEPQSDGEQVHEKDFLKEERNKLLSEVSKQKSELLRFSKT-IEEQVACQEQLK 788 Query: 322 TELTKKIELLEHLNCQIRQTNKELE------NKLATMGTESKAVSSPSKKGSPLISRKSG 375 ++ K E++ L +++ +EL N T+ E+K S + S KS Sbjct: 789 QDIQDKSEVIFSLEQKLKIVQEELVVERDRFNSELTIRDEAKEHLEKSLS-CEIDSVKSV 847 Query: 376 RNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXX 435 +N K+K Q E +Q K++ + +++ +Q N L+ + + ++ Sbjct: 848 KNDNQKLKESLEQNLGELASQ---KQLLDSAAIEIQ-ALQDQNSSLI---FQVKSLESDN 900 Query: 436 XXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKD 495 + ++ + E ++ + S I + + E V I+ Q K+EL +++ Sbjct: 901 CHLRVEIETRVQSLSDVSEEKKRLLNKISQIELQLS-ESVKTISDFQRD-KEELY--LRE 956 Query: 496 VNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSK-VSDSN 554 ++K +EK K + +I+ D + + +IK + L + QK ++ VSD N Sbjct: 957 ADLKKELEKNKQSITEISLEKDGVVELHNALIKQNQQLQEILDEKQKEALVLTQAVSDLN 1016 Query: 555 KEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLK 614 +I +E L+ ++ L+E+ G+LQ R I + K + E ET Sbjct: 1017 NKITITLKENEKLASQIVSLDEQNGSLQ---------RQINEQM-KSLTETTKERETLQN 1066 Query: 615 AISLLESQKFDLVQELH-ILQQKYD---EVEDKLADISQLQSDQVCSEIKSVHLEEQIDA 670 I E+Q + + + +L+ K D +VE+ +LQ++ + KS + Sbjct: 1067 KIQFFETQDVENHKIIEGLLKAKEDLLLQVEEHKVIEQKLQANAEMLQKKSSECTDLTQG 1126 Query: 671 LSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMN----KLQNYIQENMDLTDKLEK 726 LS +K+E+ + L+ ++ K++ +KE I+ +++ Y Q+ L D + Sbjct: 1127 LSETKEEVDHLKRKLESSNSEVV-KCKNIMLEKEKILTDQRMQIEAYQQQFKHLQDNISV 1185 Query: 727 MSAEKISELLAKINHEEQSKIQTQFGIDAKIQ-----ERDLYIENIESELSKYKSRICRL 781 + + E+ + +Q + +Q ER+L + + E+S K RL Sbjct: 1186 LQEQAFKHKSGLT--EKDTLLQKESNACVLLQKELGHERELVFTS-QQEISSLKVECSRL 1242 Query: 782 EESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDEL--VNRLAVLMDHDRV--- 836 +++ E++ +L K + ++L+E K +L +N ++ D Sbjct: 1243 NQAL---EEKENTLREKNLECQNHLEELCKRNETLVSLTSQLGLMNASIAKLESDNANLK 1299 Query: 837 --VEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQ-----QHYNALVEKANRTDLA 889 +E+ L E +EL +K QI L E Q+ +++D + N++ E + ++ Sbjct: 1300 DTLERHLSESARLKEELMQK-QIELVEYQDSGQAMNDQNSIIKSELKNSMTEMVRQKEMI 1358 Query: 890 ESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEK 949 S + +++ L S ++ EH L + + D E F TQ + L E Sbjct: 1359 TSLQNELESKRVKLGSLEEKFKSEHSQLEALQLT-LRDKEDVFQTQEMHVNNMQAKLLES 1417 Query: 950 YEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNL---ELIDKHVQKQQTQSPDYTEQ 1006 + + + +L+ + Q + +E+ + + L E + ++ + + + + Sbjct: 1418 EGQIKQRILKLQEENQSLRTALEDKDKEFSLVKTTLLAQSEACESRLKSEMVATAQFQRE 1477 Query: 1007 YIN---EINKLNALLKQKDEEIIALNQK---INNAQVSYMSMVSDYESKLAQFTTKLENM 1060 N ++N+L +++ +KD ++ +K + ++ S VS ++ Q T++++ + Sbjct: 1478 IQNLQEKMNQLISIITEKDSLLMQEKEKYMCLQSSASELESTVSQLNCQIKQLTSEIKQL 1537 Query: 1061 EEEMQRVSKQLLDSKQHNEELQILVRE--------QDDQIKELKETKLTFE----MNIPK 1108 E + + ++ ++L L + + + +K L E L E + + K Sbjct: 1538 RETQTKKEQVTFAAQSQMQKLDELYKNLQQECDLTKQELLKVLNEKSLKEEEVRKLILEK 1597 Query: 1109 TEGMIISS-TIEPMSDDANNVDXXXXXXXXXXXXLKVQE--EEEF--IQERSVLQEQSAK 1163 + + SS I+ D +N ++ ++ + EF +Q + +Q + Sbjct: 1598 EDILRTSSYQIQTTQDQQHNWRSTTMNKVEEVQAMEKKKLHKMEFMALQGKEASSDQWVQ 1657 Query: 1164 LNTELQECYTKIIQ----LETLNTELTGHDVVNQEQINQLKSKLEQLNTENDN 1212 LN LQ+C +I Q L+ LN +L + +E ++++ +Q +E N Sbjct: 1658 LNGHLQQCQLEIQQRECGLQQLNIKLQ-QTIEEKEGVSRMLKDTQQSVSELQN 1709 Score = 55.6 bits (128), Expect = 1e-05 Identities = 141/737 (19%), Positives = 300/737 (40%), Gaps = 61/737 (8%) Query: 98 LKQKEILMEKIKQYKELSKR--SSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKD 155 LK KE L+ +++++K + ++ ++ +++ +V HL ++ + Sbjct: 1086 LKAKEDLLLQVEEHKVIEQKLQANAEMLQKKSSECTDLTQGLSETKEEVDHLKRKLESSN 1145 Query: 156 NALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTK 215 + + + M E + D + +I Q + K+ +DT Sbjct: 1146 SEVVKCKNIMLEKEKILTDQRMQIEAYQQ--QFKHLQDNISVLQEQAFKHKSGLTEKDTL 1203 Query: 216 QQMTKMQENFIAMEAEWKDEKQRLL---KDIESKDVRISSLEEANKLLEAARFEISLEHS 272 Q K + ++ E E++ + ++I S V S L +A + E E +LE Sbjct: 1204 LQ--KESNACVLLQKELGHERELVFTSQQEISSLKVECSRLNQALEEKENTLREKNLECQ 1261 Query: 273 KLAQEL----EQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTE--LTK 326 +EL E +AK +E + E+ E A + E + K Sbjct: 1262 NHLEELCKRNETLVSLTSQLGLMNASIAK--LESDNANLKDTLERHLSESARLKEELMQK 1319 Query: 327 KIELLEH------LNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTAS 380 +IEL+E+ +N Q EL+N + M + + ++S + R + Sbjct: 1320 QIELVEYQDSGQAMNDQNSIIKSELKNSMTEMVRQKEMITSLQNELES--KRVKLGSLEE 1377 Query: 381 KMKSPWSQLSSETLN-QDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVIS--EKDTXXXX 437 K KS SQL + L +D + E+ M + L + K+ ++ E++ Sbjct: 1378 KFKSEHSQLEALQLTLRDKEDVFQTQEMHVNNMQAKLLESEGQIKQRILKLQEENQSLRT 1437 Query: 438 XXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEI-KDV 496 + +L+ L + E + + EI +QE++ Q ++ KD Sbjct: 1438 ALEDKDKEFSLVKTTLLAQSEACESRLKSEMVATAQFQREIQNLQEKMNQLISIITEKDS 1497 Query: 497 NVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKE 556 + EK + ++L + N + ++ S ++KQ+++T +V+ + + Sbjct: 1498 LLMQEKEKYMCLQSSASELESTVSQLNCQIKQLTS----EIKQLRETQTKKEQVTFAAQS 1553 Query: 557 IVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAI 616 ++ +EL+ Q+ +L +++ L +++ S + E +V K ++E E++ T I Sbjct: 1554 QMQKLDELYKNLQQECDLTKQE---LLKVLNEKS--LKEEEVRKLILEKEDILRTSSYQI 1608 Query: 617 SLLESQK-------FDLVQELHILQQK-YDEVEDKLADISQLQSDQVCSEIKSVHLEEQI 668 + Q+ + V+E+ +++K ++E + SDQ + HL++ Sbjct: 1609 QTTQDQQHNWRSTTMNKVEEVQAMEKKKLHKMEFMALQGKEASSDQWVQ--LNGHLQQC- 1665 Query: 669 DALSASKKELALVIENLKLDK--EQLYGTIKDLENDKEDIMNKLQN--YIQENMDLTDKL 724 L ++E L N+KL + E+ G + L++ ++ + ++LQN Y E + ++L Sbjct: 1666 -QLEIQQRECGLQQLNIKLQQTIEEKEGVSRMLKDTQQSV-SELQNRCYWLERQ-VQNQL 1722 Query: 725 EKMSAEKISELLAKINHEEQSKIQTQFGIDAK-----IQERDLYIENIESELSKYKSRIC 779 E+ E S Q G D++ + E ++++ + S L + +SR Sbjct: 1723 SPTQGSVYGEVPPGAPQEPISSTVNQVGSDSRDLRMRLSEAEIHLSQLNSRLEEERSRRE 1782 Query: 780 RLEESIAVMEDRRYSLE 796 EE++ + E R S+E Sbjct: 1783 VAEEALRLTEQRVVSME 1799 >UniRef50_UPI00006CFFCF Cluster: hypothetical protein TTHERM_00755860; n=1; Tetrahymena thermophila SB210|Rep: hypothetical protein TTHERM_00755860 - Tetrahymena thermophila SB210 Length = 1211 Score = 138 bits (334), Expect = 1e-30 Identities = 187/1001 (18%), Positives = 441/1001 (44%), Gaps = 88/1001 (8%) Query: 375 GRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTX 434 G +SP + + S+ Q + N+ I +++Q +++ + +I E D Sbjct: 192 GNKNVQNFESPNNNMESQ---QQQQQSYNEKNIKGDYVLMQKISEQQKQIQTLIDENDGL 248 Query: 435 XXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIK 494 K++L +L++ ++ ++ IH + + + K E+ + + Sbjct: 249 TRITQLLSEEKNSLKDELKILKEERIQVIHKIHEDDKIQRLKQRVKELEENNLYVRKQFS 308 Query: 495 DVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKV----KSNHKLKLKQMQKTIDNFSKV 550 ++ + +L+EK + + + D +A ++ +I + + +K ++K+++K I + Sbjct: 309 ELEI-NLLEKEATIKTYQETIQDRSEANSEKLINIYIENEEKYKKRIKELEKEIKKYENT 367 Query: 551 SDSNKEIVRLTEELHHLSQK---VAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMEN 607 ++ ++ E+ QK + +L+ + N +L L + ++ E Y K I+ E Sbjct: 368 FQ--EQTAKMNEQQIKFQQKDLSIQQLQSNQMNEKLKLQEENN----ELRKYIKQIQEEQ 421 Query: 608 LAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQS--DQVCSEIKSVHLE 665 ++KA ++ ++++ + + ++Q +++ ++ LQ D E K+V E Sbjct: 422 ----QIKAFNVSQNEQECQKELKNHIEQLNKQIQLYTEQLNNLQDNYDLKAEEYKNVLYE 477 Query: 666 EQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLE 725 D S +EL + I LK DK+ + +K + N+ + + N LQ E +L Sbjct: 478 S--DKKSKEIRELNIQIAQLKKDKDDILEKLKIMMNENDKLSNILQQKDSEQHANQQRLL 535 Query: 726 KMSA--EKISELLAKINHEE-------QSKIQTQFGIDAKIQERDLYIENIESELSKYKS 776 ++ K+SE L KIN+ E Q K Q Q + K + ++ ++ IE L + ++ Sbjct: 536 QIDGLKSKLSEQLDKINNLEKIVKEFDQFKKQ-QIIVVEKNENLNIQLQTIEKNLQEKQN 594 Query: 777 RICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRV 836 I +L ES++ + + D+ S +++ ++ + + + +++ + L + + Sbjct: 595 EIQKLNESLSEKNEIILEKAKINDEKISCIRQNEQQLIQISEKLNQVSSSLEATTKQNEL 654 Query: 837 VEKQLLEIEHENKELQKKNQILLEENQN-------LQISLSDMQQHYNALVEKANRTDLA 889 +++Q+ + + E + LQ++ Q E+ Q L++ + ++ Q ++ ++ Sbjct: 655 LQQQIAQQKKETELLQEQIQFQAEQIQQQKQQKKELELKIVNLDQELTDKKLLISQDEIQ 714 Query: 890 ESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEK 949 +E++ +L + + + + + +I + + I+ L+ + L E Sbjct: 715 ANEASSRIDKLSEALKSAEEDLRQKEIIIQELSQSIDQLQGVMKQVANDQNLEISNLKES 774 Query: 950 YEKNIEYVTQLEAQLQ-EYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYI 1008 ++K I+Y+ L AQL+ EY IE NM + L+ ++ K V + ++ + +Q Sbjct: 775 HQKEIQYLQALNAQLEKEYLKKIEEKNMKINSLDD-RIKFYKKEVSQLNEEAKENEQQIQ 833 Query: 1009 ---NEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQ 1065 +EI+ L + +I + + +N +++ ++ + Q +++ Q Sbjct: 834 MKNSEISNLKVNISDLSSQISNIAKHLNESKLCEETLQEKVINYTTQINEYKSEQQQQQQ 893 Query: 1066 RVSKQLLDSKQH-NEELQILVREQDDQIKELKETKLTFEMNIPKTE--GMIISSTIEPMS 1122 +SK + H N E Q+ V E+ +IKEL+ ++T I + E G+ + I+ + Sbjct: 894 LISKLSISYDFHSNLEKQLSVFEE--KIKELERERVTLNTKISEHESNGIETNQKIKILE 951 Query: 1123 D----------DANNVDXXXXXXXXXXXXLK-----VQEEEEFIQERSVLQEQSAKLNTE 1167 D D N L ++ EF++++ E + +L TE Sbjct: 952 DKLQFTENSYKDLQNQKSQDLEKHQNIANLSEGFQFIKSTYEFLKDKEQADE-NLRL-TE 1009 Query: 1168 LQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSA 1227 + K+ + E N++L D + ++ +NQ++ +L+ +NT+ D + ++ A Sbjct: 1010 QELIKHKLKEYEIQNSQL---DALVKQYMNQIE-QLKSVNTQKDQEIQEYKRKMMNLQDA 1065 Query: 1228 VDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIV 1287 ++ + L ++ + + E D K E S ++K + + E T + Sbjct: 1066 LN------SNLIEKSIIEEELDSIKEEK------SDLKTKMNECQLQISQIKNEST---L 1110 Query: 1288 TMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIE 1328 T E++ ++Q L ++E +NLQ+K + Q+ ++++ Sbjct: 1111 TAEEMKNIQQNLTLRKESNQNLQKKLLETSQQLAFALNQLQ 1151 Score = 117 bits (281), Expect = 3e-24 Identities = 160/829 (19%), Positives = 361/829 (43%), Gaps = 79/829 (9%) Query: 807 QEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQ 866 Q++Q++Y+E I+ D VLM +KQ+ + EN L + Q+L EE +L+ Sbjct: 210 QQQQQSYNEKNIKGDY------VLMQKISEQQKQIQTLIDENDGLTRITQLLSEEKNSLK 263 Query: 867 ISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQ-KKKEI 925 L +++ ++ K + D + + + ++++LE N + + L + +KE Sbjct: 264 DELKILKEERIQVIHKIHEDDKIQ----RLKQRVKELEENNLYVRKQFSELEINLLEKEA 319 Query: 926 EDLEIEFNTQIESAIRDKKVLN---EKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELN 982 + Q S +K++N E EK + + +LE ++++Y+N + ++N Sbjct: 320 TIKTYQETIQDRSEANSEKLINIYIENEEKYKKRIKELEKEIKKYENTFQE---QTAKMN 376 Query: 983 KMNLELIDKHVQKQQTQSPDYTE--QYINEINKLNALLK--QKDEEIIALN--QKINNAQ 1036 + ++ K + QQ QS E + E N+L +K Q++++I A N Q Q Sbjct: 377 EQQIKFQQKDLSIQQLQSNQMNEKLKLQEENNELRKYIKQIQEEQQIKAFNVSQNEQECQ 436 Query: 1037 VSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELK 1096 + + ++ +T +L N+++ +++ + +++ +RE + QI +LK Sbjct: 437 KELKNHIEQLNKQIQLYTEQLNNLQDNYDLKAEEYKNVLYESDKKSKEIRELNIQIAQLK 496 Query: 1097 ETK--LTFEMNIPKTEGMIISSTIEPMSDD--AN-----NVDXXXXXXXXXXXXLK---- 1143 + K + ++ I E +S+ ++ + AN +D + Sbjct: 497 KDKDDILEKLKIMMNENDKLSNILQQKDSEQHANQQRLLQIDGLKSKLSEQLDKINNLEK 556 Query: 1144 -VQEEEEFIQERSVLQEQSAKLNTELQ----ECYTKIIQLETLNTELTGHDVVNQEQINQ 1198 V+E ++F +++ ++ E++ LN +LQ K +++ LN L+ + + E+ Sbjct: 557 IVKEFDQFKKQQIIVVEKNENLNIQLQTIEKNLQEKQNEIQKLNESLSEKNEIILEKAKI 616 Query: 1199 LKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELR 1258 K+ + +N+ L ++E + +SS+++ + EL +Q +AQ++ + + + +++ Sbjct: 617 NDEKISCIR-QNEQQLIQISEKLNQVSSSLEATTKQ-NELLQQQIAQQKKETELLQEQIQ 674 Query: 1259 VQLSAFESKYEQLLD---SVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYAD 1315 Q + + +Q + + + QE T+K + + Q N+ + + L + + Sbjct: 675 FQAEQIQQQKQQKKELELKIVNLDQELTDKKLLISQDEIQANEASSRIDKLSEALKSAEE 734 Query: 1316 VINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENA 1375 + Q EI+ E+ +L+ +Q K++Q LN E Sbjct: 735 DLRQKEIIIQELSQSIDQLQGVMKQVANDQNLEISNLKESHQ--KEIQYLQALNAQLEKE 792 Query: 1376 QLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYT---ITLTQRND 1432 LKK R+ + +V +L + + + +I K E + + ++ + Sbjct: 793 YLKKIE-EKNMKINSLDDRIKFYKKEVSQLNEEAKENEQQIQMKNSEISNLKVNISDLSS 851 Query: 1433 EFENV--------------RQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQK 1478 + N+ +++++ Y +I + E++ + ++ K+ + + + ++K Sbjct: 852 QISNIAKHLNESKLCEETLQEKVINYTTQINEYKSEQQQQQQLIS-KLSISYDFHSNLEK 910 Query: 1479 ESEI--ERVKLIEE----LNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIE 1532 + + E++K +E LN KI+E S + + K LE+++ T L+NQ+ + Sbjct: 911 QLSVFEEKIKELERERVTLNTKISEHESNGIETNQKIKILEDKLQFTENSYKDLQNQKSQ 970 Query: 1533 IVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELL 1581 + + I NL I+ F D +Q DE L T +EL+ Sbjct: 971 DLEKHQNIANLSE----GFQFIKSTYEFLKDKEQA-DENLRLT-EQELI 1013 Score = 102 bits (245), Expect = 7e-20 Identities = 214/1046 (20%), Positives = 463/1046 (44%), Gaps = 118/1046 (11%) Query: 476 NEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAE--EQITQLNDE--IDAANKNMIKVKS 531 N++ ++ L QE N ++ ++ LK + T L+D NKN+ +S Sbjct: 143 NQVTTNEQNLAQE-NQQVAYQQIRLSASALKQLKYNNSPTVLSDYNYSGLGNKNVQNFES 201 Query: 532 -NHKLKLKQMQKTIDN----------FSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGN 580 N+ ++ +Q Q+ N K+S+ K+I L +E L++ L EEK + Sbjct: 202 PNNNMESQQQQQQSYNEKNIKGDYVLMQKISEQQKQIQTLIDENDGLTRITQLLSEEKNS 261 Query: 581 L--QLHLVDYDSGRMI----ESDVYKKMIE-MENLAETRLKAISLLESQKFDLVQELHIL 633 L +L ++ + ++I E D +++ + ++ L E L + +L+++ + Sbjct: 262 LKDELKILKEERIQVIHKIHEDDKIQRLKQRVKELEENNLYVRKQFSELEINLLEKEATI 321 Query: 634 QQKYDEVEDKL-ADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQL 692 + + ++D+ A+ +L + + +E K ++++ K E + K++++Q+ Sbjct: 322 KTYQETIQDRSEANSEKLINIYIENEEKYKKRIKELEK-EIKKYENTFQEQTAKMNEQQI 380 Query: 693 YGTIKDLE---------NDK---EDIMNKLQNY---IQENMDL----TDKLEKMSAEKIS 733 KDL N+K ++ N+L+ Y IQE + + E+ +++ Sbjct: 381 KFQQKDLSIQQLQSNQMNEKLKLQEENNELRKYIKQIQEEQQIKAFNVSQNEQECQKELK 440 Query: 734 ELLAKINH------EEQSKIQTQFGIDAKIQERDLYIENIES-ELSKYKSRICRLEESIA 786 + ++N E+ + +Q + + A+ + LY + +S E+ + +I +L++ Sbjct: 441 NHIEQLNKQIQLYTEQLNNLQDNYDLKAEEYKNVLYESDKKSKEIRELNIQIAQLKKDKD 500 Query: 787 VMEDRRYSLERKADQLGSYLQEK---QKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLE 843 + ++ + + D+L + LQ+K Q A + +Q D L ++L+ +D +EK + E Sbjct: 501 DILEKLKIMMNENDKLSNILQQKDSEQHANQQRLLQIDGLKSKLSEQLDKINNLEKIVKE 560 Query: 844 IEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTD-LAESESTKYQTQLRD 902 + + +K+ I++E+N+NL I L ++++ L EK N L ES S K + L Sbjct: 561 FD----QFKKQQIIVVEKNENLNIQLQTIEKN---LQEKQNEIQKLNESLSEKNEIILEK 613 Query: 903 LESNLKRIT----HEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVT 958 + N ++I+ +E Q + + +K +E T+ ++ + +K + ++ Sbjct: 614 AKINDEKISCIRQNEQQLIQISEKLNQVSSSLEATTKQNELLQQQIAQQKKETELLQEQI 673 Query: 959 QLEA-QLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNAL 1017 Q +A Q+Q+ K + L + + L++ EL DK + Q + + + I+KL+ Sbjct: 674 QFQAEQIQQQKQQKKELELKIVNLDQ---ELTDKKLLISQDEI--QANEASSRIDKLSEA 728 Query: 1018 LKQKDE-----EII--ALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQ 1070 LK +E EII L+Q I+ Q + +D +++ + + +Q ++ Q Sbjct: 729 LKSAEEDLRQKEIIIQELSQSIDQLQGVMKQVANDQNLEISNLKESHQKEIQYLQALNAQ 788 Query: 1071 L-LDSKQHNEELQILVREQDDQIKELKE--TKLTFEMNIPKTEGMIISSTIEPMSDDANN 1127 L + + EE + + DD+IK K+ ++L E + + + +S I + + ++ Sbjct: 789 LEKEYLKKIEEKNMKINSLDDRIKFYKKEVSQLNEEAKENEQQIQMKNSEISNLKVNISD 848 Query: 1128 VDXXXXXXXXXXXXLKVQEE---EEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTE 1184 + K+ EE E+ I + + E ++ + Q+ +K+ ++ Sbjct: 849 LSSQISNIAKHLNESKLCEETLQEKVINYTTQINEYKSE-QQQQQQLISKLSISYDFHSN 907 Query: 1185 LTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLA 1244 L V +E+I +L+ + LNT+ S E I D+ F +K Sbjct: 908 LEKQLSVFEEKIKELERERVTLNTKISEHESNGIETNQKIKILEDKLQF-TENSYKDLQN 966 Query: 1245 QREADFQKTEH--ELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDK 1302 Q+ D +K ++ L +S YE L D Q+ + N +T +++ +++KL++ Sbjct: 967 QKSQDLEKHQNIANLSEGFQFIKSTYEFLKDKEQA----DENLRLTEQEL--IKHKLKEY 1020 Query: 1303 EEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQM 1362 E L +NQIE L+S + +K D N K + Sbjct: 1021 EIQNSQLDALVKQYMNQIEQLKS-VNTQK----DQEIQEYKRKMMNLQDALNSNLIEKSI 1075 Query: 1363 QEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHE 1422 E+ + +I EE + LK ++N+ + ++ ++ ++ L E+ K + Sbjct: 1076 IEEELDSIKEEKSDLK--------------TKMNECQLQISQIKNESTLTAEEM--KNIQ 1119 Query: 1423 YTITLTQRNDEFENVRQQLVEYEKRI 1448 +TL R + +N++++L+E +++ Sbjct: 1120 QNLTL--RKESNQNLQKKLLETSQQL 1143 Score = 96.7 bits (230), Expect = 5e-18 Identities = 178/892 (19%), Positives = 376/892 (42%), Gaps = 66/892 (7%) Query: 217 QMTKMQENFIAMEAE-WKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLA 275 Q+ ++N + E + K+E+ +++ I D +I L++ K LE + + S+L Sbjct: 253 QLLSEEKNSLKDELKILKEERIQVIHKIHEDD-KIQRLKQRVKELEENNLYVRKQFSELE 311 Query: 276 QELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLN 335 L + ++ + E E EEK I + + KK E N Sbjct: 312 INLLEKEATIKTYQETIQDRSEANSEKLINIYIENEEKYKKRIKELEKEIKKYE-----N 366 Query: 336 CQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASK-MKSPWSQLSSETL 394 QT K E ++ + S + + + + N K +K + + Sbjct: 367 TFQEQTAKMNEQQIKFQQKDLSIQQLQSNQMNEKLKLQEENNELRKYIKQIQEEQQIKAF 426 Query: 395 N-----QDTDKKINKNEIAKLEMVIQSLNKDL--VDKEYVISEKDTXXXXXXXXXXGKDT 447 N Q+ K++ KN I +L IQ + L + Y + ++ K+ Sbjct: 427 NVSQNEQECQKEL-KNHIEQLNKQIQLYTEQLNNLQDNYDLKAEEYKNVLYESDKKSKEI 485 Query: 448 LIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELN-DEIKDVNVKDLIEKLK 506 +Q+ + + L + + ++++ + +Q E + ++ + + + L KL Sbjct: 486 RELNIQIAQLKKDKDDILEKLKIMMNENDKLSNILQQKDSEQHANQQRLLQIDGLKSKLS 545 Query: 507 SAEEQITQLND---EIDAANKN-MIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTE 562 ++I L E D K +I V+ N L + Q+Q TI+ + + EI +L E Sbjct: 546 EQLDKINNLEKIVKEFDQFKKQQIIVVEKNENLNI-QLQ-TIEK--NLQEKQNEIQKLNE 601 Query: 563 ELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQ 622 L ++ + E + + + ++ + + ++I+ + +K+ ++ + E K LL+ Q Sbjct: 602 SLSEKNEIILE-KAKINDEKISCIRQNEQQLIQ--ISEKLNQVSSSLEATTKQNELLQQQ 658 Query: 623 KFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQID--ALSASKKELAL 680 +E +LQ+ +++ + I Q + + E+K V+L++++ L S+ E+ Sbjct: 659 IAQQKKETELLQE---QIQFQAEQIQQQKQQKKELELKIVNLDQELTDKKLLISQDEIQA 715 Query: 681 VIENLKLDK--EQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAK 738 + ++DK E L +DL KE I+ +L I + + ++ +IS L K Sbjct: 716 NEASSRIDKLSEALKSAEEDLRQ-KEIIIQELSQSIDQLQGVMKQVANDQNLEISNL--K 772 Query: 739 INHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERK 798 +H Q +IQ ++A++++ Y++ IE + K S L++ I + L + Sbjct: 773 ESH--QKEIQYLQALNAQLEKE--YLKKIEEKNMKINS----LDDRIKFYKKEVSQLNEE 824 Query: 799 ADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQI- 857 A + +Q K S + +L ++++ + H + E +L E + K + QI Sbjct: 825 AKENEQQIQMKNSEISNLKVNISDLSSQISNIAKH--LNESKLCEETLQEKVINYTTQIN 882 Query: 858 -LLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQT 916 E Q Q +S + Y+ + + E + + + + L N K HE Sbjct: 883 EYKSEQQQQQQLISKLSISYDFHSNLEKQLSVFEEKIKELERERVTL--NTKISEHESNG 940 Query: 917 LIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNI-------EYVTQLEAQLQEYKN 969 + +K +I + +++F ++++K + + +NI +++ L++ + Sbjct: 941 IETNQKIKILEDKLQFTENSYKDLQNQKSQDLEKHQNIANLSEGFQFIKSTYEFLKDKEQ 1000 Query: 970 NIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALN 1029 ENL + +EL K L K + Q +Q +QY+N+I +L ++ QKD+EI Sbjct: 1001 ADENLRLTEQELIKHKL----KEYEIQNSQLDALVKQYMNQIEQLKSVNTQKDQEIQEYK 1056 Query: 1030 QKINNAQVSYMSMV---SDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHN 1078 +K+ N Q + S + S E +L + +++ +M Q+ K + Sbjct: 1057 RKMMNLQDALNSNLIEKSIIEEELDSIKEEKSDLKTKMNECQLQISQIKNES 1108 Score = 67.3 bits (157), Expect = 3e-09 Identities = 132/664 (19%), Positives = 293/664 (44%), Gaps = 79/664 (11%) Query: 298 QSIEPSCEEK-TEIEEKG-SLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTE 355 Q+IE + +EK EI++ SL N L K E ++C IRQ ++L + Sbjct: 583 QTIEKNLQEKQNEIQKLNESLSEKNEIILEKAKINDEKISC-IRQNEQQLIQISEKLNQV 641 Query: 356 SKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQ 415 S ++ + +K+ L + + + +++ Q +E + Q +K +LE+ I Sbjct: 642 SSSLEATTKQNELLQQQIAQQKKETELLQEQIQFQAEQIQQQKQQK------KELELKIV 695 Query: 416 SLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDV 475 +L+++L DK+ +IS+ + D L L+ + + +I E Sbjct: 696 NLDQELTDKKLLISQDEIQANEASSRI---DKLSEALKSAEEDLRQKEIIIQ-----ELS 747 Query: 476 NEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKL 535 I ++Q +KQ ND+ ++ + +L E + + + LN +++ I+ K N K+ Sbjct: 748 QSIDQLQGVMKQVANDQ--NLEISNLKESHQKEIQYLQALNAQLEKEYLKKIEEK-NMKI 804 Query: 536 -----KLKQMQKTIDNFSKVSDSNKEIVRL-TEELHHLSQKVAELEEEKGNLQLHLVDYD 589 ++K +K + ++ + N++ +++ E+ +L +++L + N+ HL + Sbjct: 805 NSLDDRIKFYKKEVSQLNEEAKENEQQIQMKNSEISNLKVNISDLSSQISNIAKHL---N 861 Query: 590 SGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLA---- 645 ++ E + +K+I T++ + Q+ L+ +L I + +E +L+ Sbjct: 862 ESKLCEETLQEKVINYT----TQINEYKSEQQQQQQLISKLSISYDFHSNLEKQLSVFEE 917 Query: 646 DISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKED 705 I +L+ ++V K E + + + ++K ++E+ E Y KDL+N K Sbjct: 918 KIKELERERVTLNTKIS--EHESNGIETNQK--IKILEDKLQFTENSY---KDLQNQKSQ 970 Query: 706 IMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIE 765 + K QN N+ + K + E + + K +E ++ Q I K++E ++ Sbjct: 971 DLEKHQNIA--NLSEGFQFIKSTYEFLKD---KEQADENLRLTEQELIKHKLKEYEIQNS 1025 Query: 766 NIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVN 825 +++ + +Y ++I +QL S +K + EY + L + Sbjct: 1026 QLDALVKQYMNQI---------------------EQLKSVNTQKDQEIQEYKRKMMNLQD 1064 Query: 826 RLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQ-NLQISLSDMQQHYNALVEKAN 884 L + ++EK ++E E ++ + ++K+ + + N+ LQIS + A K Sbjct: 1065 AL-----NSNLIEKSIIEEELDSIK-EEKSDLKTKMNECQLQISQIKNESTLTAEEMKNI 1118 Query: 885 RTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLE-IEFNTQIESAIRDK 943 + +L + + Q + LE++ + +Q +QK + ++ +E N+Q E D Sbjct: 1119 QQNLTLRKESNQNLQKKLLETSQQLAFALNQLQQIQKSRYQSPIKSVEENSQ-EQGFPDN 1177 Query: 944 KVLN 947 ++++ Sbjct: 1178 QIIS 1181 Score = 50.0 bits (114), Expect = 5e-04 Identities = 113/611 (18%), Positives = 255/611 (41%), Gaps = 67/611 (10%) Query: 154 KDNALSVLQVKMKIME-TTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXE 212 + N ++Q+ K+ + ++ L+ K NE Q A+ K T + Sbjct: 625 RQNEQQLIQISEKLNQVSSSLEATTKQNELLQQQIAQQKKETELLQEQIQFQAEQI---Q 681 Query: 213 DTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHS 272 KQQ +++ + ++ E D+K + +D + S +++ ++ L++A ++ + Sbjct: 682 QQKQQKKELELKIVNLDQELTDKKLLISQDEIQANEASSRIDKLSEALKSAEEDLR-QKE 740 Query: 273 KLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTEL-TKKIELL 331 + QEL QSI+ ++ +LEI+N+ E K+I+ L Sbjct: 741 IIIQEL------------------SQSIDQLQGVMKQVANDQNLEISNLKESHQKEIQYL 782 Query: 332 EHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSS 391 + LN Q+ KE K+ E K + K + L R K SQL+ Sbjct: 783 QALNAQL---EKEYLKKI-----EEK-----NMKINSLDDR------IKFYKKEVSQLNE 823 Query: 392 ETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQ 451 E + ++ +EI+ L++ I L+ + + ++E T I + Sbjct: 824 EAKENEQQIQMKNSEISNLKVNISDLSSQISNIAKHLNESKLCEETLQEKVINYTTQINE 883 Query: 452 LQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQ 511 + E QQ + S + + + + +++QL + + +K+L E+ Sbjct: 884 YKSEQQQQQQLISKLSISYDFH-----SNLEKQL------SVFEEKIKEL------ERER 926 Query: 512 ITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKV 571 +T LN +I N I+ K+ ++Q T +++ + + + + + + +LS+ Sbjct: 927 VT-LNTKISEHESNGIETNQKIKILEDKLQFTENSYKDLQNQKSQDLEKHQNIANLSEGF 985 Query: 572 AELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQEL- 630 ++ L+ ++ R+ E ++ K ++ + ++L A L Q + +++L Sbjct: 986 QFIKSTYEFLKDKEQADENLRLTEQELIKHKLKEYEIQNSQLDA---LVKQYMNQIEQLK 1042 Query: 631 HILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKE 690 + QK E+++ + LQ + I+ +EE++D++ K +L + +L Sbjct: 1043 SVNTQKDQEIQEYKRKMMNLQDALNSNLIEKSIIEEELDSIKEEKSDLKTKMNECQLQIS 1102 Query: 691 QLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQ 750 Q+ + ++I L + N +L KL + S ++++ L ++ ++S+ Q+ Sbjct: 1103 QIKNESTLTAEEMKNIQQNLTLRKESNQNLQKKLLETS-QQLAFALNQLQQIQKSRYQSP 1161 Query: 751 F-GIDAKIQER 760 ++ QE+ Sbjct: 1162 IKSVEENSQEQ 1172 >UniRef50_Q22W02 Cluster: Putative uncharacterized protein; n=1; Tetrahymena thermophila SB210|Rep: Putative uncharacterized protein - Tetrahymena thermophila SB210 Length = 2101 Score = 138 bits (333), Expect = 2e-30 Identities = 264/1347 (19%), Positives = 585/1347 (43%), Gaps = 124/1347 (9%) Query: 321 MTELTKKIELLEHLNCQ-IRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTA 379 M +L ++I+LL+++ Q I +L ++ S +K S S K+G + Sbjct: 393 MQKLQEEIQLLQNICVQMINMRIAQLHPFSRDSRKQTLQDSKQLEKDSD--SNKNGNDKR 450 Query: 380 SKMKSPWSQLSSETLNQDTDK--KINKNEIAKLEMVIQSLNKDLVDKEYVISE---KDTX 434 S SSE + + KIN++ K++ Q+ DL + E VIS+ Sbjct: 451 SYSVDGDLYESSEAAQNNLKQQLKINQSFDKKVQQDKQNFVNDLSEAEGVISDILSMSQI 510 Query: 435 XXXXXXXXXGKDTLIAQLQ--LEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDE 492 KD Q Q + Q+++ +L + +D+ + K + Q++N+ Sbjct: 511 SSTNYNKNFQKDGQQQQYQDYFKKNQNVD-QTLDELSEIQQDIKDSQKAL--MSQDINES 567 Query: 493 IKD--VNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKV 550 I+ VN++++ E LK E++ L + N+ + K+ + + + ++ + K Sbjct: 568 IQSYSVNIQEVQEILKDCSEKLKYLKESNMLNNQQIAKILNQVFYQFLKQEEFLSQQEKE 627 Query: 551 SDSNKEIVRLTE-ELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLA 609 + K+I L E + + + +E LQL G I+ + + Sbjct: 628 NSDEKQIRSLPNLENQSMDNQAEAIIKEHNLLQLESCCQIQGLKIDDISPFSQRFYQEIL 687 Query: 610 ETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQID 669 E + + Q+ + + Q + + + + Q+D ++ ++ +EE+I Sbjct: 688 EKHKSELEQNQKQEIQNLLDKQDQQNRLYQPQQDIRKDEMNQNDISDDKVNTIKMEEEIQ 747 Query: 670 ALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSA 729 +++ + + +L++ +L +++DK+ + K+Q IQ+ + ++LE + Sbjct: 748 KQVRIREKEIDKMYSAQLEEYKL-----QVQDDKQKELEKIQ--IQQKKQI-EQLENIIK 799 Query: 730 EKISE-LLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVM 788 E+ + + + E+ I+ Q I+ + +E+ + I+N++ E +K ++ L + I + Sbjct: 800 EQNNNHQIIQNKFIEEQNIKQQLEINLR-EEKQIAIQNLKEE---HKLQMENLMKHINCL 855 Query: 789 -EDRRYSLERKADQ-LGSYLQ---EKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLE 843 ++ + + E+ +Q L S Q EK K ++ ++ E + + ++V+E+ ++ Sbjct: 856 NQELKINQEKVKEQILHSEKQVNLEKDKLKNQESLIEQQQNQNILQQQKINQVIEEYKIQ 915 Query: 844 IEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEK-ANRTDLAESESTKYQTQLRD 902 + KEL+ + QI ++ L+I L + Q +Y E+ ++T+ ++ Q + Sbjct: 916 LNQLRKELESQ-QIQYDK---LKIELQNEQTNYLRQTEQFKSKTEELNQKNKNLQIEFEQ 971 Query: 903 LESNLKRITHE-HQTLIVQKKKEIEDLE-IEFNTQIESAIRDKKVLNEKYEKNIEY-VTQ 959 N + I + HQ +K +DLE IEF Q I K +NEK + ++ V Q Sbjct: 972 ELQNQRNIQQKLHQENEKLQKINSQDLENIEFLNQ---EINQLKEINEKNQNELKSEVKQ 1028 Query: 960 LEAQLQEYKNNIENLNMNV----EELNKMNLELIDKHVQKQQTQ-SPDYTEQYINEINKL 1014 + Q + N+ L N E++N++ E+ D +++ ++ + ++ IN I + Sbjct: 1029 YSHRCQSLQQNLIELQNNESLYNEKINQLQQEIDDLNMKANSSKLQEEQLKEQINLIKQK 1088 Query: 1015 NALLKQKDEEIIALNQ----KINNAQVSYMSMVS--------DYESKLAQFTTKLENM-- 1060 + L+Q+ +++ NQ KI N Q + + + + E K+ T+ E++ Sbjct: 1089 YSKLQQEFDQLKQFNQQQKEKIENLQRTAVEQIQIIQRLKEQECEQKIKDIITEKEDLMK 1148 Query: 1061 ------EEEMQRVSK----QLLDSKQHN--EELQILVREQDDQIKELKETKLTFEMNIPK 1108 +E+Q+ +K +LL+ +++N +E+Q +++E D QI+ +++ K+ E N Sbjct: 1149 QTVEITSKEIQKKNKLEIEKLLEQQENNKQQEIQKILKEHDQQIRSVQQ-KIE-EQN--- 1203 Query: 1109 TEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTEL 1168 E +I ++ + + +QE+E+ L+ Q+ KLN E+ Sbjct: 1204 KEDLITKQKLQSELSKCSEFQKEIFIKDQKIASV-IQEKEQLSLSIKKLEIQNQKLNDEI 1262 Query: 1169 -QECYTKIIQLETL----NTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSS 1223 Q+ T+ + E L N + +++N++ +++ +E L + N+ + + E Sbjct: 1263 IQQKQTQKHENEELRQNTNNRINELEILNKDLNKKIQDFVEILKDKEQNINNLIKEKEIE 1322 Query: 1224 ISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESK---YEQLLDSV-QSST 1279 I +D + + KQ Q A Q+ ++ QLS +S+ +Q D++ Q+ T Sbjct: 1323 IQKNIDFTNCQ--NILKQS-QQENAQLQQQVENIKQQLSQLQSQNALLQQDADNLKQNIT 1379 Query: 1280 QEETNKIVTMEQVTSLQNKL----QDKEEHLR--NLQEKYA-----DVINQ---IEILRS 1325 + + + + + SLQ ++ Q K +HLR +LQ+K +++NQ + L+S Sbjct: 1380 KTNKDNLDQKKLIESLQEQIKTADQQKSQHLRQIDLQQKALVQSEKEIVNQKMIVNELKS 1439 Query: 1326 EIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXX 1385 +I+D++ D + + ++++Q I + +N QL+K Sbjct: 1440 QIQDQENKKLALLKNEHKTMIDQQNDASNQKKIISELKQQ-ISTLENQNQQLQKQIGEDC 1498 Query: 1386 XXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYE 1445 + D +++E ++ K + + L Q N + + + Sbjct: 1499 TLQSDIIIFLKDKSNQLIETENKFNHKIIDSINTFYTLIEGLIQENKNKIEKLTSIEQKQ 1558 Query: 1446 KRIEDLTYEK--------ESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITE 1497 + + Y + +SE L+ K+ E + + + + ++ + N++I + Sbjct: 1559 DNLFSIDYNQLFRKLDTIQSETFKLKKKVIEFSKQIDNQKDQLLDSNIQQAVQKNLQIKD 1618 Query: 1498 SVSLNKQVAELNKALEEEVAKTNEMQTALENQEI--EIVTLND----EITNLQNMVRASS 1551 S +++ +L + EE + K + E QE+ +++ L E+ +QN Sbjct: 1619 FKSYFERLQKLVEN-EENLNKKYFKEITDEQQELCLKLMQLQHDIELEVFKIQNQTLEKV 1677 Query: 1552 SKIQKHVSFASDTKQGRDEQLDNTMNK 1578 K+QK + Q + E L+ +N+ Sbjct: 1678 DKVQKKIFIGGIPDQSQFENLNQNLNQ 1704 Score = 111 bits (267), Expect = 2e-22 Identities = 232/1146 (20%), Positives = 487/1146 (42%), Gaps = 98/1146 (8%) Query: 475 VNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDE-IDAANKNMIK---VK 530 +N++ Q+Q +Q + + N++ + ++ + D I ++N+I+ Sbjct: 209 INKVQNKQKQSQQTFLSKSQQQNLQKNQQMSNQNDQFSSNFQDSPIRIEDQNIIQRHNKN 268 Query: 531 SNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDS 590 N ++ L+ ++ K+ + + +++ HL K +L + L Sbjct: 269 KNEQIILQNKDQSQIEAIKLPQDCQIPLEYLKKVQHLIAKYNKLHQNSKLQNTILEQMIQ 328 Query: 591 GRMIESDVYKKMIEMENLAETRLKAISLLESQK-FDLVQELHILQQKYDEVEDKLADISQ 649 R +SD K L E +L E +K + +Q+L L ++ V DK A + + Sbjct: 329 QRQPQSDTVSKF-----LFEKYQNGKNLQELEKDYQSIQKLVELLERKILVLDK-AYLKK 382 Query: 650 LQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNK 709 Q++ V ++ L+E+I L + + + + N+++ QL+ +D + Sbjct: 383 RQNE-VQYKLIMQKLQEEIQLL----QNICVQMINMRI--AQLHPFSRDSRKQTLQDSKQ 435 Query: 710 LQNYIQENMDLTDKLEKMSAEKISEL--LAKINHEEQSKIQTQFGIDAKIQERDLYIENI 767 L+ N + DK + E A+ N ++Q KI F D K+Q+ N Sbjct: 436 LEKDSDSNKNGNDKRSYSVDGDLYESSEAAQNNLKQQLKINQSF--DKKVQQDKQNFVND 493 Query: 768 ESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQ---KAYSEYTIQEDELV 824 SE S I + + + ++ + + + Q Y ++ Q + E + + ++ Sbjct: 494 LSEAEGVISDILSMSQISSTNYNKNFQKDGQQQQYQDYFKKNQNVDQTLDELSEIQQDIK 553 Query: 825 NRLAVLMDHD-----RVVEKQLLEIEHENKELQKKNQILLEENQ-NLQISLSDMQQHYNA 878 + LM D + + E++ K+ +K + L E N N Q + Q + Sbjct: 554 DSQKALMSQDINESIQSYSVNIQEVQEILKDCSEKLKYLKESNMLNNQQIAKILNQVFYQ 613 Query: 879 LVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIES 938 +++ E E++ + Q+R L NL+ + ++Q + K+ + L++E QI+ Sbjct: 614 FLKQEEFLSQQEKENSD-EKQIRSLP-NLENQSMDNQAEAIIKEHNL--LQLESCCQIQG 669 Query: 939 A-IRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQ 997 I D ++++ + I + E + Q K I+NL ++ N++ D ++K + Sbjct: 670 LKIDDISPFSQRFYQEILEKHKSELE-QNQKQEIQNLLDKQDQQNRLYQPQQD--IRKDE 726 Query: 998 TQSPDYTEQYINEINKLNALLKQ---KDEEIIALNQKINNAQVS-YMSMVSDYESK---L 1050 D ++ +N I + KQ +++EI K+ +AQ+ Y V D + K Sbjct: 727 MNQNDISDDKVNTIKMEEEIQKQVRIREKEI----DKMYSAQLEEYKLQVQDDKQKELEK 782 Query: 1051 AQFTTK-----LENMEEEM----QRVSKQLLDSKQHNEELQILVREQDD-QIKELKET-K 1099 Q K LEN+ +E Q + + ++ + ++L+I +RE+ I+ LKE K Sbjct: 783 IQIQQKKQIEQLENIIKEQNNNHQIIQNKFIEEQNIKQQLEINLREEKQIAIQNLKEEHK 842 Query: 1100 LTFE-----MNIPKTEGMIISSTI-EPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQE 1153 L E +N E I + E + V+ ++ Q+ + +Q+ Sbjct: 843 LQMENLMKHINCLNQELKINQEKVKEQILHSEKQVNLEKDKLKNQESLIEQQQNQNILQQ 902 Query: 1154 RS---VLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTEN 1210 + V++E +LN +E ++ IQ + L EL Q Q KSK E+LN +N Sbjct: 903 QKINQVIEEYKIQLNQLRKELESQQIQYDKLKIELQNEQTNYLRQTEQFKSKTEELNQKN 962 Query: 1211 DNL-LSTVAELRS--SISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESK 1267 NL + EL++ +I + Q ++ ++ Q L E L +++ + Sbjct: 963 KNLQIEFEQELQNQRNIQQKLHQENEKLQKINSQDLENIEF--------LNQEINQLKEI 1014 Query: 1268 YEQLLDSVQSSTQEETNKIVTMEQ-VTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSE 1326 E+ + ++S ++ +++ +++Q + LQN E + LQ++ D+ ++ S+ Sbjct: 1015 NEKNQNELKSEVKQYSHRCQSLQQNLIELQNNESLYNEKINQLQQEIDDL--NMKANSSK 1072 Query: 1327 IEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXX 1386 +++E++ D + + + Q Q++ I N+ + +++ Sbjct: 1073 LQEEQLKEQINLIKQKYSKLQQEFD---QLKQFNQQQKEKIENL--QRTAVEQIQIIQRL 1127 Query: 1387 XXXXXXXRVNDAEAKVLELTHQ-LELKDSEIYQKTH-EYTITLTQR-NDEFENVRQQLVE 1443 ++ D + +L Q +E+ EI +K E L Q+ N++ + +++ L E Sbjct: 1128 KEQECEQKIKDIITEKEDLMKQTVEITSKEIQKKNKLEIEKLLEQQENNKQQEIQKILKE 1187 Query: 1444 YEKRIEDLTY---EKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVS 1500 ++++I + E+ E I + K+ + QKE I+ K+ + K S+S Sbjct: 1188 HDQQIRSVQQKIEEQNKEDLITKQKLQSELSKCSEFQKEIFIKDQKIASVIQEKEQLSLS 1247 Query: 1501 LNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSF 1560 + K + N+ L +E+ + + Q EN+E+ T N+ I L+ + + + KIQ V Sbjct: 1248 IKKLEIQ-NQKLNDEIIQQKQTQKH-ENEELRQNT-NNRINELEILNKDLNKKIQDFVEI 1304 Query: 1561 ASDTKQ 1566 D +Q Sbjct: 1305 LKDKEQ 1310 Score = 102 bits (245), Expect = 7e-20 Identities = 230/1106 (20%), Positives = 473/1106 (42%), Gaps = 131/1106 (11%) Query: 177 EKINEKD-QIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAM---EAEW 232 +KIN +D + IE N+ + + +Q+N I + E+ + Sbjct: 991 QKINSQDLENIEFLNQEINQLKEINEKNQNELKSEVKQYSHRCQSLQQNLIELQNNESLY 1050 Query: 233 KDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXX 292 ++ +L ++I+ +++ +S + + L+ I ++SKL QE +Q Sbjct: 1051 NEKINQLQQEIDDLNMKANSSKLQEEQLKEQINLIKQKYSKLQQEFDQLKQFNQQQKEKI 1110 Query: 293 XXLAKQSIEP----------SCEEK-----TEIEE--KGSLEIANMTELTK-KIELLEHL 334 L + ++E CE+K TE E+ K ++EI + K K+E+ + L Sbjct: 1111 ENLQRTAVEQIQIIQRLKEQECEQKIKDIITEKEDLMKQTVEITSKEIQKKNKLEIEKLL 1170 Query: 335 NCQIRQTNKELENKLATMGTESKAVSSPSKKGSP--LISRKSGRNTASKMKSPWSQL--- 389 Q +E++ L + ++V ++ + LI+++ ++ SK ++ Sbjct: 1171 EQQENNKQQEIQKILKEHDQQIRSVQQKIEEQNKEDLITKQKLQSELSKCSEFQKEIFIK 1230 Query: 390 SSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLI 449 + + +K+ I KLE+ Q LN + +I +K T + I Sbjct: 1231 DQKIASVIQEKEQLSLSIKKLEIQNQKLNDE------IIQQKQTQKHENEELRQNTNNRI 1284 Query: 450 AQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQ----LKQELNDEI-KDVNVKDLIEK 504 +L++ ++ + +D EI K +EQ L +E EI K+++ + Sbjct: 1285 NELEILNKD---------LNKKIQDFVEILKDKEQNINNLIKEKEIEIQKNIDFTNCQNI 1335 Query: 505 LKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEEL 564 LK ++++ QL +++ + + +++S + L + N +K + N + +L E L Sbjct: 1336 LKQSQQENAQLQQQVENIKQQLSQLQSQNALLQQDADNLKQNITKTNKDNLDQKKLIESL 1395 Query: 565 HHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKF 624 +++ +++K L +D +++S+ K+++ + + I E++K Sbjct: 1396 Q---EQIKTADQQKSQ-HLRQIDLQQKALVQSE--KEIVNQKMIVNELKSQIQDQENKKL 1449 Query: 625 DLVQELH--ILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVI 682 L++ H ++ Q+ D K IS+L+ E ++ L++QI + ++ + Sbjct: 1450 ALLKNEHKTMIDQQNDASNQKKI-ISELKQQISTLENQNQQLQKQIGEDCTLQSDIIIF- 1507 Query: 683 ENLKLDKEQLYGTIKDLENDKEDIMNK----LQNYIQENMDLTDKLEKMSAEKISELLAK 738 LK QL T + D +N ++ IQEN + +KL S E+ + L Sbjct: 1508 --LKDKSNQLIETENKFNHKIIDSINTFYTLIEGLIQENKNKIEKLT--SIEQKQDNLFS 1563 Query: 739 INHEEQSK----IQTQ-FGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRY 793 I++ + + IQ++ F + K+ E I+N + +L S I + + ++D + Sbjct: 1564 IDYNQLFRKLDTIQSETFKLKKKVIEFSKQIDNQKDQL--LDSNIQQAVQKNLQIKDFKS 1621 Query: 794 SLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKE--- 850 ER + + +K + E T ++ EL +L L HD +E ++ +I+++ E Sbjct: 1622 YFERLQKLVENEENLNKKYFKEITDEQQELCLKLMQLQ-HD--IELEVFKIQNQTLEKVD 1678 Query: 851 -LQKK-------NQILLEE-NQNLQISLSDMQQHYNALVEKANRT--DLAESESTKYQTQ 899 +QKK +Q E NQNL S + + + +A T D + E+ + + Sbjct: 1679 KVQKKIFIGGIPDQSQFENLNQNLNQIFSKFENDFKQVTTQAQGTYWDYGK-ENRLLERK 1737 Query: 900 LRDLESNLKRITHEHQTLIVQ-KKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIE--Y 956 L D+ +K++ ++ +Q +KKE++DL+ FN QI + ++ LN K++ IE + Sbjct: 1738 LIDIYEEVKKMREGQFSMKMQLRKKEMQDLD-SFN-QISKNLVNQ--LN-KFQTIIEGLH 1792 Query: 957 VTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNA 1016 VTQ Y N++ N N + +++ + + +P +I N++N Sbjct: 1793 VTQFSPVRSSY--NVDLFNQNSDG------DVV------RSSSNP-----FIKNGNQINL 1833 Query: 1017 LLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEE--MQRVSKQLLDS 1074 +K + + +K++ Q + + +S+ E F EN+ E+ ++ + + S Sbjct: 1834 FGSRKSQILQQKFEKVDEKQENEENAISEIEDDDEDFKKFQENLIEDSDQSQIQSKEITS 1893 Query: 1075 KQHNEELQILVREQDDQ-IKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXX 1133 Q+ LQ ++QDD+ + L F+ N T I P+ + N D Sbjct: 1894 LQNLSTLQSPQKKQDDKRVSSASAIALAFQ-NEGGTSSNTSLGKISPLRESMTNFDGMRQ 1952 Query: 1134 XXXXXXXXLKVQEEEEFIQE--RSVLQEQSAKLNTELQ----ECYTKIIQ--LETLNTEL 1185 + Q FI E + + Q +N+ LQ E K ++ +ETL TEL Sbjct: 1953 SVSRIEN--EDQRNIRFILEELKKIKQNVEKVVNSLLQYNFEEIKIKTLKQTIETLETEL 2010 Query: 1186 TGHDVVNQEQINQLKSKLEQLNTEND 1211 T + Q+ + ++ ++L D Sbjct: 2011 TEYKNYYQQSVGYIQGVFDELQQIGD 2036 Score = 92.3 bits (219), Expect = 1e-16 Identities = 181/921 (19%), Positives = 389/921 (42%), Gaps = 71/921 (7%) Query: 212 EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271 E + Q Q+ + E+K + +L K++ES+ ++ L + E+ E Sbjct: 892 EQQQNQNILQQQKINQVIEEYKIQLNQLRKELESQQIQYDKL----------KIELQNEQ 941 Query: 272 SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTEL-TKKIEL 330 + ++ EQ L + E + + I++K E + ++ ++ +E Sbjct: 942 TNYLRQTEQFKSKTEELNQKNKNL-QIEFEQELQNQRNIQQKLHQENEKLQKINSQDLEN 1000 Query: 331 LEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLS 390 +E LN +I Q + E + +E K S + + +N S +QL Sbjct: 1001 IEFLNQEINQLKEINEKNQNELKSEVKQYSHRCQSLQQNLIEL--QNNESLYNEKINQLQ 1058 Query: 391 SETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIA 450 E D + K N +++ + E + + +N L+ ++Y S+ + I Sbjct: 1059 QEI--DDLNMKANSSKLQE-EQLKEQIN--LIKQKY--SKLQQEFDQLKQFNQQQKEKIE 1111 Query: 451 QLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQL-KQELNDEIKDVNVKDLIEKLKSAE 509 LQ + ++ + + + +I +E L KQ + K++ K+ +E K E Sbjct: 1112 NLQRTAVEQIQIIQRLKEQECEQKIKDIITEKEDLMKQTVEITSKEIQKKNKLEIEKLLE 1171 Query: 510 EQITQLNDEIDAANKNMIKVKSNHKLKLKQMQK-TIDNFSKVSDSNKEIVRLTEELHHLS 568 +Q EI K + + + K+++ K + K+ + +E+ Sbjct: 1172 QQENNKQQEIQKILKEHDQQIRSVQQKIEEQNKEDLITKQKLQSELSKCSEFQKEIFIKD 1231 Query: 569 QKVAELEEEKGNLQLHL--VDYDSGRMIESDVYKKMI---EMENLAETRLKAISLLESQK 623 QK+A + +EK L L + ++ + ++ + + +K E E L + I+ LE Sbjct: 1232 QKIASVIQEKEQLSLSIKKLEIQNQKLNDEIIQQKQTQKHENEELRQNTNNRINELEILN 1291 Query: 624 FDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALV-- 681 DL ++ +Q + ++DK +I+ L ++ K++ + L S++E A + Sbjct: 1292 KDLNKK---IQDFVEILKDKEQNINNLIKEKEIEIQKNIDFTNCQNILKQSQQENAQLQQ 1348 Query: 682 -IENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKIN 740 +EN+K QL L+ D +++ + ++N+D +K E + E +I Sbjct: 1349 QVENIKQQLSQLQSQNALLQQDADNLKQNITKTNKDNLD-----QKKLIESLQE---QIK 1400 Query: 741 HEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKAD 800 +Q K Q ID +Q++ L E E+ K + L+ I E+++ +L + Sbjct: 1401 TADQQKSQHLRQID--LQQKALV--QSEKEIVNQKMIVNELKSQIQDQENKKLALLKNEH 1456 Query: 801 QLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKEL-----QKKN 855 + + + ++ A ++ I EL +++ L + ++ ++KQ+ E ++ K N Sbjct: 1457 K--TMIDQQNDASNQKKI-ISELKQQISTLENQNQQLQKQIGEDCTLQSDIIIFLKDKSN 1513 Query: 856 QILLEENQ-NLQI--SLSDMQQHYNALV-EKANRTDLAESESTKYQTQLRDLESN-LKRI 910 Q++ EN+ N +I S++ L+ E N+ + S K Q L ++ N L R Sbjct: 1514 QLIETENKFNHKIIDSINTFYTLIEGLIQENKNKIEKLTSIEQK-QDNLFSIDYNQLFRK 1572 Query: 911 THEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNN 970 Q+ + KK++ IEF+ QI++ +D+ + + NI+ Q Q++++K+ Sbjct: 1573 LDTIQSETFKLKKKV----IEFSKQIDNQ-KDQLL-----DSNIQQAVQKNLQIKDFKSY 1622 Query: 971 IENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQ 1030 E L VE +N + + +QQ + + ++ + Q E++ + + Sbjct: 1623 FERLQKLVENEENLNKKYFKEITDEQQELCLKLMQLQHDIELEVFKIQNQTLEKVDKVQK 1682 Query: 1031 KINNAQVSYMSMVSDYESKLAQFTTKLEN-MEEEMQRVSKQLLDSKQHNEELQILVREQD 1089 KI + S + L Q +K EN ++ + D + N L+ + + Sbjct: 1683 KIFIGGIPDQSQFENLNQNLNQIFSKFENDFKQVTTQAQGTYWDYGKENRLLERKLIDIY 1742 Query: 1090 DQIKELKETKLTFEMNIPKTE 1110 +++K+++E + + +M + K E Sbjct: 1743 EEVKKMREGQFSMKMQLRKKE 1763 Score = 50.8 bits (116), Expect = 3e-04 Identities = 131/812 (16%), Positives = 339/812 (41%), Gaps = 73/812 (8%) Query: 297 KQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTES 356 +Q+I +EK EIE + +++ N + K+ + N Q++Q + ++ +L+ + +++ Sbjct: 1309 EQNINNLIKEK-EIEIQKNIDFTNCQNILKQSQ---QENAQLQQQVENIKQQLSQLQSQN 1364 Query: 357 KAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQS 416 + + I++ + N K Q +T +Q + + + ++ + + ++QS Sbjct: 1365 ALLQQDADNLKQNITKTNKDNLDQKKLIESLQEQIKTADQQKSQHLRQIDLQQ-KALVQS 1423 Query: 417 LNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVN 476 K++V+++ +++E + + ++ Q I + + ++ Sbjct: 1424 -EKEIVNQKMIVNELKSQIQDQENKKLALLKNEHKTMIDQQNDASNQKKI-ISELKQQIS 1481 Query: 477 EIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDE-----IDAAN------KN 525 + +QL++++ ++ D+I LK Q+ + ++ ID+ N + Sbjct: 1482 TLENQNQQLQKQIGEDC--TLQSDIIIFLKDKSNQLIETENKFNHKIIDSINTFYTLIEG 1539 Query: 526 MIKVKSNHKLKLKQMQKTIDNFSKVSDSN--KEIVRLTEELHHLSQKVAELEEEKGNLQL 583 +I+ N KL +++ DN + + +++ + E L +KV E ++ N + Sbjct: 1540 LIQENKNKIEKLTSIEQKQDNLFSIDYNQLFRKLDTIQSETFKLKKKVIEFSKQIDNQKD 1599 Query: 584 HLVDYDSGRMIESDV----YKKMIE-MENLAETRLKAISLLESQKFDLVQELHI-LQQKY 637 L+D + + ++ ++ +K E ++ L E + D QEL + L Q Sbjct: 1600 QLLDSNIQQAVQKNLQIKDFKSYFERLQKLVENEENLNKKYFKEITDEQQELCLKLMQLQ 1659 Query: 638 DEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIK 697 ++E ++ ++Q+ Q ++ V + I + + ENL + Q++ Sbjct: 1660 HDIE---LEVFKIQN-QTLEKVDKVQKKIFIGGIPDQSQ-----FENLNQNLNQIFSKF- 1709 Query: 698 DLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAK- 756 END + + + Q + K ++ K+ ++ ++ + + + + K Sbjct: 1710 --ENDFKQVTTQAQGTYWDY----GKENRLLERKLIDIYEEVKKMREGQFSMKMQLRKKE 1763 Query: 757 IQERDLYIE---NIESELSKYKSRICRLEESIAVMEDRRYSLER-KADQLGSYLQEKQKA 812 +Q+ D + + N+ ++L+K+++ I L + Y+++ + G ++ Sbjct: 1764 MQDLDSFNQISKNLVNQLNKFQTIIEGLHVTQFSPVRSSYNVDLFNQNSDGDVVRSSSNP 1823 Query: 813 YSEYTIQEDELVNRLAVLMDH--DRVVEKQ------LLEIEHENKELQKKNQILLEENQN 864 + + Q + +R + ++ ++V EKQ + EIE ++++ +K + L+E++ Sbjct: 1824 FIKNGNQINLFGSRKSQILQQKFEKVDEKQENEENAISEIEDDDEDFKKFQENLIEDSDQ 1883 Query: 865 LQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKE 924 QI + + N + L + + ++ + +E T + Sbjct: 1884 SQIQSKE-------ITSLQNLSTLQSPQKKQDDKRVSSASAIALAFQNEGGTSSNTSLGK 1936 Query: 925 IEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIEN-----LNMNVE 979 I L E T + + + + ++NI ++ + +L++ K N+E L N E Sbjct: 1937 ISPLR-ESMTNFDGMRQSVSRIENEDQRNIRFILE---ELKKIKQNVEKVVNSLLQYNFE 1992 Query: 980 ELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSY 1039 E+ L+ + ++ + T+ +Y +Q + I + L+Q + + +Q + Sbjct: 1993 EIKIKTLKQTIETLETELTEYKNYYQQSVGYIQGVFDELQQIGDPVYQFSQMNTIFKKCC 2052 Query: 1040 MSMVSDYESKLAQFTTKLENMEEEMQRVSKQL 1071 + Y+ ++ +N E+ + KQL Sbjct: 2053 TDLQEFYKKQIQSQDCAEQNQVIEVIQQVKQL 2084 >UniRef50_A0EHS3 Cluster: Chromosome undetermined scaffold_97, whole genome shotgun sequence; n=2; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_97, whole genome shotgun sequence - Paramecium tetraurelia Length = 2950 Score = 138 bits (333), Expect = 2e-30 Identities = 238/1165 (20%), Positives = 486/1165 (41%), Gaps = 91/1165 (7%) Query: 472 TEDVNE---IAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEID--AANKNM 526 T+D N+ I +V E KQ+ + D+ K+L+ +++ E Q+T E++ A+ Sbjct: 554 TQDKNQKTIIDEVNEGTKQQSSKVSLDLQNKELVVEVE--ENQVTFKPKEVEKQGASLEQ 611 Query: 527 IKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLV 586 ++KS K ++Q K K D K I ++ + ++++ Q Sbjct: 612 QQMKSQKKPIIQQNYKESIQKQKDDDIEKPIDESSQNQAN-DNTISKIPNTDSQQQFK-- 668 Query: 587 DYDSGRMIESDVYKKMIEMENLAETRLKAISLLES----QKFDLVQELHILQQKYDEVED 642 D ++ ++ +++ K + E K +E+ Q Q+++ LQQ ++ Sbjct: 669 DKNNKQIQIANLDNKQSQKEQTQSISQKEPQKIENPQNQQNNQQKQKVNNLQQNKSSDQN 728 Query: 643 KLADISQL-QSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLEN 701 L + L Q+ Q ++++ + + + +K+ N + DK+Q T ++ + Sbjct: 729 NLENKKDLLQNQQENNQVQKIETTQDGNKNQFLRKQNT----NQQQDKDQQQETQQEHQI 784 Query: 702 DKEDIMNKLQNYIQEN---MDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQ 758 K+ NKL +E ++L + EK AE+ L + +E+ Q + D + Q Sbjct: 785 QKDGQQNKLVEEEKEKDRQLELQRQQEKQQAEQQKRLEEEQKEQEKKDRQLELQKDQERQ 844 Query: 759 ERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTI 818 + + +N E K K R L++ E +R E++ +L +EK++ Sbjct: 845 QAEQ--QNKLEEEQKEKERQLELQK-----EQQRQQAEQQK-KLDEEQKEKERQLQLQKE 896 Query: 819 QEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNA 878 QE + + L + + E+QL E++ E + Q + Q LEE Q + ++Q+ Sbjct: 897 QERQQAEQQKKLEEEQKEKERQL-ELQKEQERQQAEQQKKLEEEQKEKERQLELQKQQEQ 955 Query: 879 LVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIE-DLEIEFNTQIE 937 ++A + E E + QL +L+ +R E Q + +++KE E LE++ + + Sbjct: 956 --QQAEQQKKLEDEQKEKNRQL-ELQKEQERQQAEQQKKLEEEQKEKERQLELQKEQERQ 1012 Query: 938 SAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLEL-IDKHVQKQ 996 A + KK+ E+ E+ QLE Q ++ + E EE + +L + K ++Q Sbjct: 1013 QAEQQKKIEEEQKEQE----RQLEIQKEQERQQAEQQKKLDEEQKEKERQLELQKEQERQ 1068 Query: 997 QTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVS-YMSMVSDYESKLAQFTT 1055 Q + E+ E + K+++++ +K+ + + M + E + A+ Sbjct: 1069 QVEQQKKLEEEQKEKERKLEQQKEQEKQQAEQKKKLEEEEKERQLEMQKEQERQQAEQQK 1128 Query: 1056 KLENME------------EEMQRVSKQL-LDSKQHNEELQI-LVREQDDQIKELKETKLT 1101 KLE + +E+Q+V +Q +D +Q +E + L +EQ++Q + ++ KL Sbjct: 1129 KLEEEQKEKERQLELQKGQELQQVEQQKKIDEEQKEKERSLGLQKEQENQ--QAEQQKLL 1186 Query: 1102 FEMNIPKTEGMIISSTIEPM-SDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQ 1160 E N K + + EP ++ ++ K Q+ ++ Q + + +EQ Sbjct: 1187 EEENKEKERQLQLQKEQEPQQAEQQKKLEEEQKEKERQLEQQKEQDRQKVEQSKKLEEEQ 1246 Query: 1161 SAK-LNTELQECYT-------KIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDN 1212 K ELQ+ K ++ E E QEQ + + KLE+ E + Sbjct: 1247 KEKERQIELQKVQENQQTEQQKRLEEEQKEKERQLQLQREQEQQAEQQKKLEEEQQEKER 1306 Query: 1213 LLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQ--LSAFESKYEQ 1270 L EL+ + ++ E E +Q Q+E D Q+ E + +++ A E + EQ Sbjct: 1307 QL----ELQKQQAEQQKKQEEEQKEKERQLELQKEQDRQQAEEQKKIEEEQKAKELQLEQ 1362 Query: 1271 LLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEE-----HLRNLQEKYADVINQIEILRS 1325 + + +++ K+ +Q Q +LQ ++E + L+E+ + Q+E+ + Sbjct: 1363 QKEQERQQAEQQ-KKLEEEQQEKERQLELQKEQEKQQAEQQKRLEEEQKEKERQLELQKE 1421 Query: 1326 EIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQE-QSILNINEENAQLKKSSXXX 1384 + + E Q +Q ++ + E +L+K Sbjct: 1422 QERQQAEQQKKLEEEQKEKERQLELQKEQERQQAEQQKKLEEEQKEKERQLELQKEQERQ 1481 Query: 1385 XXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEY 1444 + + LEL + E + +E +K E ++ + + +Q E Sbjct: 1482 LAEQQKKLEEEQKEKERQLELQKEQERQQAEQQKKLEEEQKEKERQLELQKEQERQQAEQ 1541 Query: 1445 EKRIEDLTYEKESELAILRLKMHENANHY-----ETMQKESEIERVKLIEELNV----KI 1495 +K++E+ EKE +L + + + + A E +KE ++E K E V K+ Sbjct: 1542 QKKLEEEQKEKERQLELQKQQEQQQAEQQKKLEEEQKEKERQLELQKEQERQQVEQQKKL 1601 Query: 1496 TESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQ 1555 E ++ EL K E+E + + Q + Q+ EIV D++ Q+ S + Sbjct: 1602 EEDQKEKERQLELQK--EQEKQQAEQQQIDQQQQQKEIVINQDQLQQPQHNAEPQSHPVS 1659 Query: 1556 KHVSFASD-TKQGRDEQLDNTMNKE 1579 S D Q ++ +N++ ++ Sbjct: 1660 LQQSQLIDQNAQNQNNNNNNSLKQQ 1684 Score = 132 bits (319), Expect = 8e-29 Identities = 272/1392 (19%), Positives = 569/1392 (40%), Gaps = 100/1392 (7%) Query: 215 KQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAAR-----FEISL 269 +QQ + E +E E K+++++ + KD E+ NKL E + E+ Sbjct: 808 RQQEKQQAEQQKRLEEEQKEQEKKDRQLELQKDQERQQAEQQNKLEEEQKEKERQLELQK 867 Query: 270 EHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIE 329 E + E ++ L K+ E++ ++EE+ E EL K+ E Sbjct: 868 EQQRQQAEQQKKLDEEQKEKERQLQLQKEQERQQAEQQKKLEEE-QKEKERQLELQKEQE 926 Query: 330 LLE-HLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQ 388 + ++ + KE E +L + + + KK K+ + K + Sbjct: 927 RQQAEQQKKLEEEQKEKERQLELQKQQEQQQAEQQKKLEDEQKEKNRQLELQKEQERQQA 986 Query: 389 LSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTL 448 + L ++ +K + E+ K + Q+ + +++E +K+ + Sbjct: 987 EQQKKLEEEQKEKERQLELQKEQERQQAEQQKKIEEE----QKEQERQLEIQKEQERQQA 1042 Query: 449 IAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSA 508 Q +L+ +Q + L + E +V++Q K E + K+ ++ E+ K Sbjct: 1043 EQQKKLDEEQKEKERQL-----ELQKEQERQQVEQQKKLEEEQKEKERKLEQQKEQEKQQ 1097 Query: 509 EEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLS 568 EQ +L +E + ++++ + + + QK ++ K + E+ + E Sbjct: 1098 AEQKKKLEEE---EKERQLEMQKEQERQQAEQQKKLEEEQKEKERQLELQKGQELQQVEQ 1154 Query: 569 QKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQ 628 QK + E+++ L L + E +K++E EN + R + L + Q+ + Sbjct: 1155 QKKIDEEQKEKERSLGLQKEQENQQAEQ---QKLLEEENKEKER--QLQLQKEQEPQQAE 1209 Query: 629 ELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLD 688 + L+++ E E +L Q + D+ E +S LEE+ + EL V EN + + Sbjct: 1210 QQKKLEEEQKEKERQLE--QQKEQDRQKVE-QSKKLEEE-QKEKERQIELQKVQENQQTE 1265 Query: 689 KEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQ 748 +++ +++ + +KE + +LQ ++ + KLE+ EK +L + EQ K Q Sbjct: 1266 QQK---RLEEEQKEKERQL-QLQREQEQQAEQQKKLEEEQQEKERQLELQKQQAEQQKKQ 1321 Query: 749 TQFGIDAKIQERDLYIENIESELSKYKSRICRLEESI--AVMEDRRYSLERKADQ---LG 803 + + K +ER L ++ + + + E+ +E ++ ++A+Q L Sbjct: 1322 EE---EQKEKERQLELQKEQDRQQAEEQKKIEEEQKAKELQLEQQKEQERQQAEQQKKLE 1378 Query: 804 SYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQ 863 QEK++ QE + + L + + E+Q LE++ E + Q + Q LEE Q Sbjct: 1379 EEQQEKERQLELQKEQEKQQAEQQKRLEEEQKEKERQ-LELQKEQERQQAEQQKKLEEEQ 1437 Query: 864 NLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKK 923 + ++Q+ ++A + E E + + QL +L+ +R E Q + +++K Sbjct: 1438 KEKERQLELQKEQER--QQAEQQKKLEEEQKEKERQL-ELQKEQERQLAEQQKKLEEEQK 1494 Query: 924 EIE-DLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELN 982 E E LE++ + + A + KK+ E+ EK QLE Q ++ + E EE Sbjct: 1495 EKERQLELQKEQERQQAEQQKKLEEEQKEKE----RQLELQKEQERQQAEQQKKLEEEQK 1550 Query: 983 KMNLEL-IDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMS 1041 + +L + K ++QQ + E+ E + L K+++ + + +K+ Q Sbjct: 1551 EKERQLELQKQQEQQQAEQQKKLEEEQKEKERQLELQKEQERQQVEQQKKLEEDQ---KE 1607 Query: 1042 MVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLT 1101 E + Q + E + + Q+ K+++ ++ ++ Q Q + L++++L Sbjct: 1608 KERQLELQKEQEKQQAEQQQIDQQQQQKEIVINQDQLQQPQHNAEPQSHPV-SLQQSQL- 1665 Query: 1102 FEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQS 1161 + N +S + D + +D + Q +F+QE S++ + Sbjct: 1666 IDQNAQNQNNNNNNSLKQQTFGDLSKIDQEPGKSPSEIQKSESQHSRKFVQEPSIMIKTP 1725 Query: 1162 AKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELR 1221 K + Q+ + ET N E VV EQI K + N T L Sbjct: 1726 PK---QQQKTF------ETFNEE----KVVQAEQIASPKEVKIGNDIPQYNQTGTFVGL- 1771 Query: 1222 SSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQE 1281 S D R E ++ Q Q+E K +++ + + S +++ SS + Sbjct: 1772 -SEQQIPDTRRKEGSDNQSQGEQQQEI---KQQNDQKTDKTVSRSSIQKVNSRPPSSKGQ 1827 Query: 1282 ETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXX 1341 E +T+E Q + Q+ + R+ Q + EI++ E + + Sbjct: 1828 EKKAPLTLE-----QQQQQESAQTNRSEQPHDKEKTQSKEIIQQEQNESQSQKPQSQSGI 1882 Query: 1342 XXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAK 1401 +T + Q + + ++ N+ +KKS+ N + Sbjct: 1883 RSIKSAGKRGEKTNPEQPSQKEGDNTQQPDQTNS-VKKSNKITPKIQSRPLSGAN----Q 1937 Query: 1402 VLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIED---LTYE-KES 1457 +EL+ K+S + + T E +++++ +N +L E + IED LT + Sbjct: 1938 PIELSRPNSTKNS-VKKITIEQQQMKQEQSNQQDNKPPELTESQLSIEDAKRLTQTMSQQ 1996 Query: 1458 ELAILRLKMHENANHYETMQKES-EIERVKLIEELNVKITESVSL------NKQVAELNK 1510 +L + +L+ E A+H + Q+ + + + + + N +I SL K+V + N+ Sbjct: 1997 DLPVKQLQ--ETASHPQLQQQANPQTQNQQQSSKNNSRIQSGKSLQKSDRTQKKVEQPNQ 2054 Query: 1511 ALEEEVAKTNEMQTALENQEIEIV---TLNDEITNLQNMVRASSSKIQKHVSFASDTKQG 1567 +++ K + QT E+Q EI T+ E + ++S+++ Q + S + Sbjct: 2055 DSTQQLEKDQQPQTKSEDQNKEIKDSNTIKSEGKSKGGSNKSSNAQQQPIQNEESKPQSA 2114 Query: 1568 RDEQLDNTMNKE 1579 +D+Q T ++ Sbjct: 2115 KDKQKPVTKEQQ 2126 Score = 124 bits (300), Expect = 2e-26 Identities = 212/1076 (19%), Positives = 447/1076 (41%), Gaps = 69/1076 (6%) Query: 235 EKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXX 294 + Q+ KD +K ++I++L+ E + IS + + + + Sbjct: 662 DSQQQFKDKNNKQIQIANLDNKQSQKEQTQ-SISQKEPQKIENPQNQQNNQQKQKVNNLQ 720 Query: 295 LAKQSIEPSCEEKTEI----EEKGSLEIANMTELTKKIELLEHLNC-----QIRQTNKEL 345 K S + + E K ++ +E ++ T+ K + L N + +Q + Sbjct: 721 QNKSSDQNNLENKKDLLQNQQENNQVQKIETTQDGNKNQFLRKQNTNQQQDKDQQQETQQ 780 Query: 346 ENKLATMGTESKAVSSPSKKGSPL-ISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINK 404 E+++ G ++K V +K L + R+ + A + K +L E Q+ KK + Sbjct: 781 EHQIQKDGQQNKLVEEEKEKDRQLELQRQQEKQQAEQQK----RLEEEQKEQE--KKDRQ 834 Query: 405 NEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPS 464 E+ K + Q+ ++ +++E +K+ + Q +L+ +Q + Sbjct: 835 LELQKDQERQQAEQQNKLEEE----QKEKERQLELQKEQQRQQAEQQKKLDEEQKEKERQ 890 Query: 465 LIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANK 524 L E + A+ Q++L++E ++ + + ++ E+ + EQ +L +E + Sbjct: 891 L---QLQKEQERQQAEQQKKLEEEQKEKERQLELQK--EQERQQAEQQKKLEEE-QKEKE 944 Query: 525 NMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLH 584 ++++ + + + QK +++ K + E+ + E QK E E+++ QL Sbjct: 945 RQLELQKQQEQQQAEQQKKLEDEQKEKNRQLELQKEQERQQAEQQKKLEEEQKEKERQLE 1004 Query: 585 LVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKL 644 L + E +K IE E + R LE QK Q+ Q+K DE + + Sbjct: 1005 LQKEQERQQAEQ---QKKIEEEQKEQERQ-----LEIQKEQERQQAE-QQKKLDEEQKEK 1055 Query: 645 ADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKE 704 +LQ +Q ++ EQ L +KE +E K ++Q K LE +++ Sbjct: 1056 ERQLELQKEQERQQV------EQQKKLEEEQKEKERKLEQQKEQEKQQAEQKKKLEEEEK 1109 Query: 705 DIMNKLQNYIQ-ENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLY 763 + ++Q + + + KLE+ EK +L + E Q +++ Q ID + +E++ Sbjct: 1110 ERQLEMQKEQERQQAEQQKKLEEEQKEKERQLELQKGQELQ-QVEQQKKIDEEQKEKERS 1168 Query: 764 IENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDEL 823 + ++ E ++ +L E ++R+ L++ +Q ++++K E +E +L Sbjct: 1169 L-GLQKEQENQQAEQQKLLEEENKEKERQLQLQK--EQEPQQAEQQKKLEEEQKEKERQL 1225 Query: 824 VNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKA 883 + D +V + + LE E + KE Q + Q + E Q Q + +Q + Sbjct: 1226 EQQKE--QDRQKVEQSKKLEEEQKEKERQIELQKVQENQQTEQQKRLEEEQKEKERQLQL 1283 Query: 884 NRTDLAESESTKY---QTQLRDLESNLKRITHEHQTLIVQKKKEIE-DLEIEFNTQIESA 939 R ++E K + Q ++ + L++ E Q +++KE E LE++ + A Sbjct: 1284 QREQEQQAEQQKKLEEEQQEKERQLELQKQQAEQQKKQEEEQKEKERQLELQKEQDRQQA 1343 Query: 940 IRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLEL-IDKHVQKQQT 998 KK+ E+ K + QLE Q ++ + E EE + +L + K +KQQ Sbjct: 1344 EEQKKIEEEQKAKEL----QLEQQKEQERQQAEQQKKLEEEQQEKERQLELQKEQEKQQA 1399 Query: 999 QSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLE 1058 + E+ E + L K+++ + +K+ Q + + + Q + + Sbjct: 1400 EQQKRLEEEQKEKERQLELQKEQERQQAEQQKKLEEEQKEKERQLELQKEQERQQAEQQK 1459 Query: 1059 NMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTI 1118 +EEE + +QL K+ +L ++ +++ KE KE +L + + + Sbjct: 1460 KLEEEQKEKERQLELQKEQERQLAEQQKKLEEEQKE-KERQLELQKEQERQQAEQQKKLE 1518 Query: 1119 EPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSV-LQEQSAKLNTELQECYTKIIQ 1177 E + ++ K EEE+ +ER + LQ+Q + E Q+ + + Sbjct: 1519 EEQKEKERQLELQKEQERQQAEQQKKLEEEQKEKERQLELQKQQEQQQAEQQKKLEEEQK 1578 Query: 1178 LETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAE 1237 + EL ++Q+ Q K KLE+ E + L E +Q+ + + Sbjct: 1579 EKERQLELQKEQ--ERQQVEQQK-KLEEDQKEKERQLELQKEQE---KQQAEQQQIDQQQ 1632 Query: 1238 LWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVT 1293 K+ + ++ Q+ +H Q + QL+D Q++ + N +++Q T Sbjct: 1633 QQKEIVINQD-QLQQPQHNAEPQSHPVSLQQSQLID--QNAQNQNNNNNNSLKQQT 1685 Score = 124 bits (298), Expect = 3e-26 Identities = 257/1376 (18%), Positives = 564/1376 (40%), Gaps = 114/1376 (8%) Query: 233 KDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXX 292 K +KQ+ +D K + I + E K ++++ + L++ +L E+E+ Sbjct: 548 KTDKQKT-QDKNQKTI-IDEVNEGTKQ-QSSKVSLDLQNKELVVEVEENQVTFKPKEVEK 604 Query: 293 XXLAKQSIEPSCEEKTEIEE--KGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLA 350 + + + ++K I++ K S++ ++ K I+ Q N +K+ Sbjct: 605 QGASLEQQQMKSQKKPIIQQNYKESIQKQKDDDIEKPID-----ESSQNQANDNTISKIP 659 Query: 351 TMGTESKAVSSPSKKG--SPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIA 408 ++ + +K+ + L +++S + + Q NQ +++ K ++ Sbjct: 660 NTDSQQQFKDKNNKQIQIANLDNKQSQKEQTQSISQKEPQKIENPQNQQNNQQ--KQKVN 717 Query: 409 KLEMVIQSLNKDLVDKEYVIS---EKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSL 465 L+ S +L +K+ ++ E + K+ + + QQ + Sbjct: 718 NLQQNKSSDQNNLENKKDLLQNQQENNQVQKIETTQDGNKNQFLRKQNTNQQQDKDQQQ- 776 Query: 466 IHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKN 525 T+ ++I K +Q K ++ KD ++ ++ K EQ +L +E K Sbjct: 777 -----ETQQEHQIQKDGQQNKLVEEEKEKDRQLELQRQQEKQQAEQQKRLEEEQKEQEKK 831 Query: 526 --MIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQL 583 ++++ + + + + Q ++ K + E+ + + QK + E+++ QL Sbjct: 832 DRQLELQKDQERQQAEQQNKLEEEQKEKERQLELQKEQQRQQAEQQKKLDEEQKEKERQL 891 Query: 584 HLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDK 643 L + E KK+ E + E +L+ L + Q+ ++ L+++ E E + Sbjct: 892 QLQKEQERQQAEQQ--KKLEEEQKEKERQLE---LQKEQERQQAEQQKKLEEEQKEKERQ 946 Query: 644 LADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDK 703 L ++ + Q Q + K + E++ ++L L E + EQ +++ + +K Sbjct: 947 L-ELQKQQEQQQAEQQKKLEDEQK-----EKNRQLELQKEQERQQAEQ-QKKLEEEQKEK 999 Query: 704 EDIMNKLQNYIQENMDLTDKLEKMSAEKISEL-LAKINHEEQSKIQTQFGIDAKIQERDL 762 E + + ++ + K+E+ E+ +L + K +Q++ Q + + K +ER L Sbjct: 1000 ERQLELQKEQERQQAEQQKKIEEEQKEQERQLEIQKEQERQQAEQQKKLDEEQKEKERQL 1059 Query: 763 YIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDE 822 EL K + R + E +E+ + ERK +Q QEKQ+A + ++E+E Sbjct: 1060 -------ELQKEQER--QQVEQQKKLEEEQKEKERKLEQQKE--QEKQQAEQKKKLEEEE 1108 Query: 823 LVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEK 882 +L + + +R +Q ++E E KE K+ Q+ L++ Q LQ VE+ Sbjct: 1109 KERQLEMQKEQERQQAEQQKKLEEEQKE--KERQLELQKGQELQ------------QVEQ 1154 Query: 883 ANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIE-DLEIEFNTQIESAIR 941 + D E K + + L+ + E Q L+ ++ KE E L+++ + + A + Sbjct: 1155 QKKID----EEQKEKERSLGLQKEQENQQAEQQKLLEEENKEKERQLQLQKEQEPQQAEQ 1210 Query: 942 DKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLEL-IDKHVQKQQTQS 1000 KK+ E+ EK QLE Q ++ + +E EE + ++ + K + QQT+ Sbjct: 1211 QKKLEEEQKEKE----RQLEQQKEQDRQKVEQSKKLEEEQKEKERQIELQKVQENQQTEQ 1266 Query: 1001 PDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENM 1060 E+ E K L Q+++E A QK ++ + + +L + + + Sbjct: 1267 QKRLEEEQKE--KERQLQLQREQEQQAEQQK----KLEEEQQEKERQLELQKQQAEQQKK 1320 Query: 1061 EEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEP 1120 +EE Q+ ++ L+ ++ + Q +++ ++ ++ KE +L + + + E Sbjct: 1321 QEEEQKEKERQLELQKEQDRQQAEEQKKIEEEQKAKELQLEQQKEQERQQAEQQKKLEEE 1380 Query: 1121 MSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSV-LQEQSAKLNTELQECYTKIIQLE 1179 + ++ K EEE+ +ER + LQ++ + E Q+ + + + Sbjct: 1381 QQEKERQLELQKEQEKQQAEQQKRLEEEQKEKERQLELQKEQERQQAEQQKKLEEEQKEK 1440 Query: 1180 TLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELW 1239 EL ++Q Q K KLE+ E + L E ++ + E E Sbjct: 1441 ERQLELQKEQ--ERQQAEQQK-KLEEEQKEKERQLELQKEQERQLAEQQKKLEEEQKEKE 1497 Query: 1240 KQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTS----- 1294 +Q Q+E + Q+ E + +++ E + + L Q Q E K + EQ Sbjct: 1498 RQLELQKEQERQQAEQQKKLEEEQKEKERQLELQKEQERQQAEQQKKLEEEQKEKERQLE 1557 Query: 1295 LQNKLQDKE-EHLRNLQEKYADVINQIEIL----RSEIEDE-KVAFXXXXXXXXXXXXXX 1348 LQ + + ++ E + L+E+ + Q+E+ R ++E + K+ Sbjct: 1558 LQKQQEQQQAEQQKKLEEEQKEKERQLELQKEQERQQVEQQKKLEEDQKEKERQLELQKE 1617 Query: 1349 XXDLRTENQSYKQMQEQSILNINEENAQL-KKSSXXXXXXXXXXXXRVNDAEAKVLELTH 1407 + E Q Q Q+Q + IN++ Q + ++ ++ D A+ + Sbjct: 1618 QEKQQAEQQQIDQQQQQKEIVINQDQLQQPQHNAEPQSHPVSLQQSQLIDQNAQ-----N 1672 Query: 1408 QLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMH 1467 Q ++ + Q+T + Q + + Q+ R + +E + +++ Sbjct: 1673 QNNNNNNSLKQQTFGDLSKIDQEPGKSPSEIQKSESQHSR----KFVQEPSI-MIKTPPK 1727 Query: 1468 ENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQ---- 1523 + +ET +E ++ ++ VKI + Q E+++ T + Sbjct: 1728 QQQKTFETFNEEKVVQAEQIASPKEVKIGNDIPQYNQTGTFVGLSEQQIPDTRRKEGSDN 1787 Query: 1524 TALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKE 1579 + Q+ EI ND+ T+ S S IQK V+ + +G++++ T+ ++ Sbjct: 1788 QSQGEQQQEIKQQNDQKTD----KTVSRSSIQK-VNSRPPSSKGQEKKAPLTLEQQ 1838 Score = 119 bits (287), Expect = 6e-25 Identities = 193/1042 (18%), Positives = 444/1042 (42%), Gaps = 67/1042 (6%) Query: 527 IKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLV 586 ++ + NH Q QK + S ++ N EI K +EK Sbjct: 452 LEQQKNHSGDNSQHQKFHEESS--NEMNNEIPNQQRTKTEEQGKAKNQFKEKFGFSESHP 509 Query: 587 DYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLAD 646 D + + E ++ + L+ + +++ + ESQ+ ++ + + D++ + Sbjct: 510 DQEPQQPKEQFTFQGNSDPYRLSSIKERSMEIGESQRVKTDKQ-KTQDKNQKTIIDEVNE 568 Query: 647 ISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDL--ENDKE 704 ++ QS +V ++++ L +++ + K + + L+++Q+ K + +N KE Sbjct: 569 GTKQQSSKVSLDLQNKELVVEVEENQVTFKPKEVEKQGASLEQQQMKSQKKPIIQQNYKE 628 Query: 705 DIMNKLQNYIQENMDL----------------TDKLEKMSAEKISEL-LAKINHEEQSKI 747 I + + I++ +D TD ++ + ++ +A +++++ K Sbjct: 629 SIQKQKDDDIEKPIDESSQNQANDNTISKIPNTDSQQQFKDKNNKQIQIANLDNKQSQKE 688 Query: 748 QTQFGIDAKIQERDLYIENIESELS-KYKSRICRLEESIAVMEDRRYSLERKADQLGSYL 806 QTQ I K ++ IEN +++ + + K ++ L+++ + ++ +LE K D L + Sbjct: 689 QTQ-SISQKEPQK---IENPQNQQNNQQKQKVNNLQQNKSSDQN---NLENKKDLLQNQQ 741 Query: 807 QEKQKAYSEYTIQ--EDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQ- 863 + Q E T +++ + + D+ ++Q + EH+ ++ ++N+++ EE + Sbjct: 742 ENNQVQKIETTQDGNKNQFLRKQNTNQQQDKD-QQQETQQEHQIQKDGQQNKLVEEEKEK 800 Query: 864 NLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKK 923 + Q+ L Q+ A E+ R + + E K QL +L+ + +R E Q + +++K Sbjct: 801 DRQLELQRQQEKQQA--EQQKRLEEEQKEQEKKDRQL-ELQKDQERQQAEQQNKLEEEQK 857 Query: 924 EIE-DLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELN 982 E E LE++ Q + A + KK+ E+ EK QL+ Q ++ + E EE Sbjct: 858 EKERQLELQKEQQRQQAEQQKKLDEEQKEKE----RQLQLQKEQERQQAEQQKKLEEEQK 913 Query: 983 KMNLEL-IDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMS 1041 + +L + K ++QQ + E+ E + L KQ++++ +K+ + Q Sbjct: 914 EKERQLELQKEQERQQAEQQKKLEEEQKEKERQLELQKQQEQQQAEQQKKLEDEQKEKNR 973 Query: 1042 MVSDYESKLAQFTTKLENMEEEMQRVSKQL-LDSKQHNEELQILVREQDDQIKELKETKL 1100 + + + Q + + +EEE + +QL L +Q ++ + + +++Q ++ ++ ++ Sbjct: 974 QLELQKEQERQQAEQQKKLEEEQKEKERQLELQKEQERQQAEQQKKIEEEQKEQERQLEI 1033 Query: 1101 TFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQ 1160 E + E E + ++ K EEE+ +ER + Q++ Sbjct: 1034 QKEQERQQAEQQ--KKLDEEQKEKERQLELQKEQERQQVEQQKKLEEEQKEKERKLEQQK 1091 Query: 1161 SAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAEL 1220 + Q+ K ++ E +L ++Q Q K KLE+ E + L + Sbjct: 1092 EQEKQQAEQK---KKLEEEEKERQLEMQKEQERQQAEQQK-KLEEEQKEKERQLE--LQK 1145 Query: 1221 RSSISSAVDQRGFEIAELWKQHL--AQREADFQKTEHELRVQLSAFESKYEQLLDSVQSS 1278 + Q+ + + K+ Q+E + Q+ E + ++ E + + L Q Sbjct: 1146 GQELQQVEQQKKIDEEQKEKERSLGLQKEQENQQAEQQKLLEEENKEKERQLQLQKEQEP 1205 Query: 1279 TQEETNKIVTMEQVTS----LQNKLQDKE--EHLRNLQEKYADVINQIEILRSEIEDEKV 1332 Q E K + EQ Q K QD++ E + L+E+ + QIE+ + + E+++ Sbjct: 1206 QQAEQQKKLEEEQKEKERQLEQQKEQDRQKVEQSKKLEEEQKEKERQIELQKVQ-ENQQ- 1263 Query: 1333 AFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXX 1392 L+ + + +Q ++Q L ++ + + Sbjct: 1264 --TEQQKRLEEEQKEKERQLQLQREQEQQAEQQKKLEEEQQEKERQLELQKQQAEQQKKQ 1321 Query: 1393 XRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLT 1452 + + LEL + + + +E +K E + ++ + +Q E +K++E+ Sbjct: 1322 EEEQKEKERQLELQKEQDRQQAEEQKKIEEEQKAKELQLEQQKEQERQQAEQQKKLEEEQ 1381 Query: 1453 YEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKAL 1512 EKE +L + + + + A + +++E + E+ + +E + + K++ E K Sbjct: 1382 QEKERQLELQKEQEKQQAEQQKRLEEEQK-EKERQLELQKEQERQQAEQQKKLEEEQKEK 1440 Query: 1513 EE--EVAKTNEMQTALENQEIE 1532 E E+ K E Q A + +++E Sbjct: 1441 ERQLELQKEQERQQAEQQKKLE 1462 Score = 105 bits (253), Expect = 8e-21 Identities = 165/821 (20%), Positives = 352/821 (42%), Gaps = 54/821 (6%) Query: 212 EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDV-RISSLEEANKLLEAARFEISLE 270 +D ++Q + Q+N + E + K+ + L K+ + + + L+E K E + ++ E Sbjct: 839 KDQERQQAE-QQNKLEEEQKEKERQLELQKEQQRQQAEQQKKLDEEQKEKER-QLQLQKE 896 Query: 271 HSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIEL 330 + E ++ L K+ E++ ++EE+ E EL K+ E Sbjct: 897 QERQQAEQQKKLEEEQKEKERQLELQKEQERQQAEQQKKLEEEQK-EKERQLELQKQQEQ 955 Query: 331 LE-HLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQL 389 + ++ KE +L + + + KK K + K + Sbjct: 956 QQAEQQKKLEDEQKEKNRQLELQKEQERQQAEQQKKLEEEQKEKERQLELQKEQERQQAE 1015 Query: 390 SSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLI 449 + + ++ ++ + EI K + Q+ + +D+E +K+ + + Sbjct: 1016 QQKKIEEEQKEQERQLEIQKEQERQQAEQQKKLDEE----QKEKERQLELQKEQERQQVE 1071 Query: 450 AQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAE 509 Q +LE +Q + L E E K Q + K++L +E K+ ++ E+ + Sbjct: 1072 QQKKLEEEQKEKERKL-------EQQKEQEKQQAEQKKKLEEEEKERQLEMQKEQERQQA 1124 Query: 510 EQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQ 569 EQ +L +E + ++++ +L+ + QK ID K + + + + E Q Sbjct: 1125 EQQKKLEEE-QKEKERQLELQKGQELQQVEQQKKIDEEQKEKERSLGLQKEQENQQAEQQ 1183 Query: 570 KVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQE 629 K+ E E ++ QL L + E KK+ E + E +L+ + QK V++ Sbjct: 1184 KLLEEENKEKERQLQLQKEQEPQQAEQQ--KKLEEEQKEKERQLEQQKEQDRQK---VEQ 1238 Query: 630 LHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLE--EQIDALSASKKELALVIENLKL 687 L+++ E E ++ ++ ++Q +Q + K + E E+ L +++ + KL Sbjct: 1239 SKKLEEEQKEKERQI-ELQKVQENQQTEQQKRLEEEQKEKERQLQLQREQEQQAEQQKKL 1297 Query: 688 DKEQLYGTIKDLENDKEDI-MNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSK 746 ++EQ + LE K+ K Q Q+ + +L+K + +E KI E+++K Sbjct: 1298 EEEQQEKE-RQLELQKQQAEQQKKQEEEQKEKERQLELQKEQDRQQAEEQKKIEEEQKAK 1356 Query: 747 ---IQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLG 803 ++ Q + + E+ +E + E + + + + +E + +R E+K + Sbjct: 1357 ELQLEQQKEQERQQAEQQKKLEEEQQEKER-QLELQKEQEKQQAEQQKRLEEEQKEKERQ 1415 Query: 804 SYLQ---EKQKAYSEYTIQED--ELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQIL 858 LQ E+Q+A + ++E+ E +L + + +R +Q ++E E KE +++ ++ Sbjct: 1416 LELQKEQERQQAEQQKKLEEEQKEKERQLELQKEQERQQAEQQKKLEEEQKEKERQLELQ 1475 Query: 859 LEENQNL---QISLSDMQQHYNALVE--------KANRTDLAESESTKYQTQLRDLESNL 907 E+ + L Q L + Q+ +E +A + E E + + QL +L+ Sbjct: 1476 KEQERQLAEQQKKLEEEQKEKERQLELQKEQERQQAEQQKKLEEEQKEKERQL-ELQKEQ 1534 Query: 908 KRITHEHQTLIVQKKKEIE-DLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQE 966 +R E Q + +++KE E LE++ + + A + KK+ E+ EK QLE Q ++ Sbjct: 1535 ERQQAEQQKKLEEEQKEKERQLELQKQQEQQQAEQQKKLEEEQKEKE----RQLELQKEQ 1590 Query: 967 YKNNIENLNMNVEELNKMNLEL-IDKHVQKQQTQSPDYTEQ 1006 + +E E+ + +L + K +KQQ + +Q Sbjct: 1591 ERQQVEQQKKLEEDQKEKERQLELQKEQEKQQAEQQQIDQQ 1631 Score = 70.1 bits (164), Expect = 5e-10 Identities = 137/702 (19%), Positives = 280/702 (39%), Gaps = 48/702 (6%) Query: 882 KANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIR 941 K ++ ES+ K Q + + N K I E Q+ ++ L+++ N ++ + Sbjct: 535 KERSMEIGESQRVKTDKQ-KTQDKNQKTIIDEVNEGTKQQSSKVS-LDLQ-NKELVVEVE 591 Query: 942 DKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHV-QKQQTQS 1000 + +V + E + + + Q++ K I N E + K + I+K + + Q Q+ Sbjct: 592 ENQVTFKPKEVEKQGASLEQQQMKSQKKPIIQQNYK-ESIQKQKDDDIEKPIDESSQNQA 650 Query: 1001 PDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYE-SKLAQFTTKLEN 1059 D T I + + +++I N +Q +S E K+ + N Sbjct: 651 NDNTISKIPNTDSQQQFKDKNNKQIQIANLDNKQSQKEQTQSISQKEPQKIENPQNQQNN 710 Query: 1060 MEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIE 1119 +++ +Q S Q+N E + + + + ++++ + T + N K + + +T + Sbjct: 711 QQKQKVNNLQQNKSSDQNNLENKKDLLQNQQENNQVQKIETTQDGN--KNQFLRKQNTNQ 768 Query: 1120 PMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQE-CYTKIIQL 1178 D K+ EEE+ + LQ Q K E Q+ + + Sbjct: 769 QQDKDQQQETQQEHQIQKDGQQNKLVEEEKEKDRQLELQRQQEKQQAEQQKRLEEEQKEQ 828 Query: 1179 ETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAEL 1238 E + +L ++Q Q ++KLE+ E + L E + + + E E Sbjct: 829 EKKDRQLELQKDQERQQAEQ-QNKLEEEQKEKERQLELQKEQQRQQAEQQKKLDEEQKEK 887 Query: 1239 WKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNK 1298 +Q Q+E + Q+ E + +++ E + + L Q Q E K + EQ K Sbjct: 888 ERQLQLQKEQERQQAEQQKKLEEEQKEKERQLELQKEQERQQAEQQKKLEEEQ------K 941 Query: 1299 LQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQS 1358 ++++ L+ QE+ Q E + ++EDE+ R + + Sbjct: 942 EKERQLELQKQQEQ-----QQAE-QQKKLEDEQ-------KEKNRQLELQKEQERQQAEQ 988 Query: 1359 YKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQ 1418 K+++E+ E +L+K + + LE+ + E + +E + Sbjct: 989 QKKLEEEQ--KEKERQLELQKEQERQQAEQQKKIEEEQKEQERQLEIQKEQERQQAEQQK 1046 Query: 1419 KTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQK 1478 K E ++ + + +Q VE +K++E+ EKE +L + + + A + +++ Sbjct: 1047 KLDEEQKEKERQLELQKEQERQQVEQQKKLEEEQKEKERKLEQQKEQEKQQAEQKKKLEE 1106 Query: 1479 ESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALE-NQEIEIVTLN 1537 E + ++++ +E +Q AE K LEEE K E Q L+ QE++ V Sbjct: 1107 EEKERQLEMQKEQE----------RQQAEQQKKLEEE-QKEKERQLELQKGQELQQVEQQ 1155 Query: 1538 DEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKE 1579 +I Q + S +QK + +Q ++L NKE Sbjct: 1156 KKIDEEQK-EKERSLGLQKE----QENQQAEQQKLLEEENKE 1192 Score = 67.7 bits (158), Expect = 2e-09 Identities = 195/1092 (17%), Positives = 432/1092 (39%), Gaps = 69/1092 (6%) Query: 212 EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFE----I 267 E K+Q + E +E E K EK+R IE + V+ + E K LE + E + Sbjct: 1226 EQQKEQDRQKVEQSKKLEEEQK-EKER---QIELQKVQENQQTEQQKRLEEEQKEKERQL 1281 Query: 268 SLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKK 327 L+ + Q+ EQ L Q + ++K E E+K + + + Sbjct: 1282 QLQREQ-EQQAEQQKKLEEEQQEKERQLELQKQQAEQQKKQEEEQKEKERQLELQKEQDR 1340 Query: 328 IELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWS 387 + E + Q KEL+ L + + + KK K + K + Sbjct: 1341 QQAEEQKKIEEEQKAKELQ--LEQQKEQERQQAEQQKKLEEEQQEKERQLELQKEQEKQQ 1398 Query: 388 QLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDT 447 + L ++ +K + E+ K + Q+ + +++E +K+ + Sbjct: 1399 AEQQKRLEEEQKEKERQLELQKEQERQQAEQQKKLEEE----QKEKERQLELQKEQERQQ 1454 Query: 448 LIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKS 507 Q +LE +Q + L E ++A+ Q++L++E ++ + + ++ E+ + Sbjct: 1455 AEQQKKLEEEQKEKERQL---ELQKEQERQLAEQQKKLEEEQKEKERQLELQK--EQERQ 1509 Query: 508 AEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHL 567 EQ +L +E + ++++ + + + QK ++ K + E+ + E+ Sbjct: 1510 QAEQQKKLEEE-QKEKERQLELQKEQERQQAEQQKKLEEEQKEKERQLELQKQQEQQQAE 1568 Query: 568 SQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLV 627 QK E E+++ QL L + +E KK+ E + E +L+ L + Q+ Sbjct: 1569 QQKKLEEEQKEKERQLELQKEQERQQVEQQ--KKLEEDQKEKERQLE---LQKEQEKQQA 1623 Query: 628 QELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKL 687 ++ I QQ+ + ++ + + QLQ Q +E +S + Q L + N L Sbjct: 1624 EQQQIDQQQ--QQKEIVINQDQLQQPQHNAEPQSHPVSLQQSQLIDQNAQNQNNNNNNSL 1681 Query: 688 DKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKI 747 K+Q +G + ++ + +++Q E+ +++ S ++ K ++Q K Sbjct: 1682 -KQQTFGDLSKIDQEPGKSPSEIQK--SESQHSRKFVQEPS------IMIKTPPKQQQKT 1732 Query: 748 QTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQ 807 F + K+ + + E ++ + + + + E + RK Sbjct: 1733 FETFN-EEKVVQAEQIASPKEVKIGNDIPQYNQTGTFVGLSEQQIPDTRRKEGSDNQSQG 1791 Query: 808 EKQKAYSEYTIQE-DELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQ 866 E+Q+ + Q+ D+ V+R ++ + R +K +KK + LE+ Q + Sbjct: 1792 EQQQEIKQQNDQKTDKTVSRSSIQKVNSR---------PPSSKGQEKKAPLTLEQQQQQE 1842 Query: 867 ISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIE 926 + ++ + + EK ++ + E + Q+Q +S ++ I + ++ Sbjct: 1843 SAQTNRSEQPHDK-EKTQSKEIIQQEQNESQSQKPQSQSGIRSIKSAGKRGEKTNPEQPS 1901 Query: 927 DLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMN-VEELNKMN 985 E + NTQ K N K I+ L Q + + N N V+++ Sbjct: 1902 QKEGD-NTQQPDQTNSVKKSN-KITPKIQS-RPLSGANQPIELSRPNSTKNSVKKITIEQ 1958 Query: 986 LELIDKHVQKQQTQSPDYTEQY--INEINKLNALLKQKDEEIIALNQKINNAQVSYMS-- 1041 ++ + +Q + P+ TE I + +L + Q+D + L + ++ Q+ + Sbjct: 1959 QQMKQEQSNQQDNKPPELTESQLSIEDAKRLTQTMSQQDLPVKQLQETASHPQLQQQANP 2018 Query: 1042 -----MVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELK 1096 S + Q L+ + ++V + DS Q E+ Q + +DQ KE+K Sbjct: 2019 QTQNQQQSSKNNSRIQSGKSLQKSDRTQKKVEQPNQDSTQQLEKDQQPQTKSEDQNKEIK 2078 Query: 1097 ETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSV 1156 ++ T + K++G S+ N K Q++ Q+ V Sbjct: 2079 DSN-TIKSE-GKSKGGSNKSSNAQQQPIQNEESKPQSAKDKQKPVTKEQQQPVQNQDEQV 2136 Query: 1157 LQEQSA--KLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLL 1214 ++Q ++ + + I++++ ++ + G +NQ + + K + + E + ++ Sbjct: 2137 FRQQQTIEQIKDKANQEDIPQIKVQSPHSSMKGSQDMNQLEASLHKDD-QVVEQEQEQVV 2195 Query: 1215 STVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQL-LD 1273 +++ + S+ Q + E Q ++E Q + +++ S + EQ + Sbjct: 2196 EQNQDIQ-EVRSSNQQDQEQANENAIQQNNEQEKQEQNNDQDVKGPKSEQNGQEEQEGMK 2254 Query: 1274 SVQSSTQEETNK 1285 S S+ ++TNK Sbjct: 2255 SSDSNRSQKTNK 2266 >UniRef50_A0D3I1 Cluster: Chromosome undetermined scaffold_36, whole genome shotgun sequence; n=2; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_36, whole genome shotgun sequence - Paramecium tetraurelia Length = 1351 Score = 137 bits (332), Expect = 2e-30 Identities = 212/1085 (19%), Positives = 474/1085 (43%), Gaps = 87/1085 (8%) Query: 478 IAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKL 537 + ++QEQ KQ D++ D N+ E++ E+Q++Q+ ++ A K+ + N+K + Sbjct: 267 VLQLQEQRKQI--DKMVDQNIYQ--EQICQYEQQLSQIQSQLRQAQKDNENLTQNYKKAM 322 Query: 538 KQMQK-TIDNFSKVSDSNKEIVRLTEEL-HHLSQKVAELEEEKGNLQLHLVDYDSGRMIE 595 ++ K +I++ + + S K+ ++ EE+ + Q + LE + Q +++++ + Sbjct: 323 QKYNKLSINSEEQNTSSLKQRLQELEEICKNKDQLYSVLERSNNDSQHRNINFENQITQQ 382 Query: 596 SD----VYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQ 651 + + K+ E + L +++ ++++ L Q +L + LQQ +K+ ++S+ Sbjct: 383 NQQLLQLKNKLDEKDILIDSQKESLNNLNLQLLNLQNQNCSLQQNEKIHNEKIDELSK-- 440 Query: 652 SDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQ 711 + + +EQI+ S K+ ++L LD + ++EN + + NK Sbjct: 441 --------QIIQQQEQINQQSIEIKKQCE--DHLSLDNQ-------NIENLTQQLNNK-N 482 Query: 712 NYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESEL 771 N + E ++ ++ ++ ELL +I ++Q K Q Q ++ K E++ +N ++EL Sbjct: 483 NELAEYQTQCEQQKQKHQLEVEELLKQIQQQKQEKEQIQADLEQKYMEKE---KNFQNEL 539 Query: 772 SKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQ--EDELVNRLAV 829 + + R L + V+ + L++ + + Q +K + + + E +L N+L Sbjct: 540 KQQQEREEELSTKVQVLIQQTNQLQQLINDSTNQAQVMRKLFLDPQNESAEADLPNQLME 599 Query: 830 LMDHDRVVEKQLLE-IEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKAN-RTD 887 L + +L + +E +K++Q+ + + N Q L + Q + +A + D Sbjct: 600 LNKAIALKFCKLKQDLEQNSKQIQEYEIEDSKNSYNQQSLLIEQLQLTTIELNQAKQKID 659 Query: 888 LAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKK--EIEDLEIEFNTQIESAIRDKKV 945 +SE+ Q Q+ ++N + + + +Q + Q +K +++LEI+ I+ +I +K++ Sbjct: 660 NLQSENALLQKQM---QTNSEFLNNLNQLTLQQNEKIQNLQNLEIQNKDLIQQSISEKQI 716 Query: 946 LNEKYEKNIEYVTQ----------LEAQLQEYKNNIENLNMNVEELNKMNLE--LIDKHV 993 + E+NI + Q L+ ++ + ++ I NL+ + +LN+ N E +I++ + Sbjct: 717 NQQLSEQNIIFDQQNQDLQIKLQALQIEILKKEDLINNLSSKISQLNQQNQEQVIINEQL 776 Query: 994 QKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQF 1053 Q Q +S T++ E Q++E + N + + ++ + ++ Sbjct: 777 QFQIKESIHNTQELQQENQISKTQYDQQNENLTMQNSTLEKEIIQLKDQITILDEQVNNL 836 Query: 1054 TTKLENME--EEMQRVSKQLLDSKQHNEELQ--ILVREQD-----DQIKELKETKLTFEM 1104 K++ +E +++ Q D Q +++Q + V+EQD DQ+++ + + + Sbjct: 837 NQKIKELEILNSLKQDEIQQQDQIQQQDQIQQQVQVQEQDQTQQYDQLQQQVQLQDQVQQ 896 Query: 1105 --NIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEE---EEFIQERSVLQE 1159 N + II T + + ++ L E E+ + + ++E Sbjct: 897 KDNQDNKQNEIIQQTYQEIGIQTEQLEQQQVINLELNSQLAEPLEINKEQHSKLQQQIEE 956 Query: 1160 QSAKLN---TELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLST 1216 + +LN T LQ+ I Q++ NT L + + + ++EQL N+ S Sbjct: 957 LTIQLNQQTTALQQAQNDIDQMKIENTSLVKSHEMQLLREGEFTLQIEQLIEINEQKSSK 1016 Query: 1217 VAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQ 1276 + EL + I + Q +I EL +Q L ++ K + ++ + E K +L + ++ Sbjct: 1017 IEELETQIKESQLQYQNDIQEL-QQQLFTENDEWLKEKEIIQQYIDQLEHKGLELTNQIK 1075 Query: 1277 SSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXX 1336 E N +Q++ LQ E + L+++ + + E EI + + Sbjct: 1076 VKDDEIQNIQKQNQQLSDQLEGLQIVNEKAQQLEKQCLENKQKFEQQIDEINLKNILKNN 1135 Query: 1337 XXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVN 1396 D + + K+ E+ +I E++ K + R+ Sbjct: 1136 DFIKQIQQLQQQSQDDQVKLLELKKQLEEKEESIKEKDG---KHAIEIQLITNNYVNRLK 1192 Query: 1397 DAEAKVLELT------HQLELKDSEIYQKTHEYTITLTQRNDE-FENVRQQLVEYEKRIE 1449 D + + L Q+EL + + L Q+ E FE +++ + EK I+ Sbjct: 1193 DKDDVIQNLQQEIQSYQQVELDQQNLIKFLENVKENLEQQKSENFEYIQEIQLTNEKIIQ 1252 Query: 1450 DLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELN 1509 ++ EL I +L++ E E E E++ + + E+ SLN+ N Sbjct: 1253 Q---SEQQELQINQLQV--TIKELEQKNHELETEKINISNNYQQALIEAQSLNQTQDNSN 1307 Query: 1510 KALEE 1514 + +E+ Sbjct: 1308 EIIEK 1312 Score = 133 bits (321), Expect = 4e-29 Identities = 216/1048 (20%), Positives = 437/1048 (41%), Gaps = 95/1048 (9%) Query: 331 LEHLNCQIRQTNKELEN-----KLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSP 385 L + Q+RQ K+ EN K A +++S + S L R K K Sbjct: 297 LSQIQSQLRQAQKDNENLTQNYKKAMQKYNKLSINSEEQNTSSLKQRLQELEEICKNKDQ 356 Query: 386 WSQLSSETLNQDTDKKIN-KNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXG 444 + + N + IN +N+I + + L L +K+ +I + Sbjct: 357 LYSVLERSNNDSQHRNINFENQITQQNQQLLQLKNKLDEKDILIDSQKESLNNLNLQLLN 416 Query: 445 KDTLIAQLQLEHQQHMEGPSLI--HVGTNTEDVNEIA-KVQEQLKQELNDEIKDVNVKDL 501 LQ + H E + + E +N+ + ++++Q + L+ + + N+++L Sbjct: 417 LQNQNCSLQQNEKIHNEKIDELSKQIIQQQEQINQQSIEIKKQCEDHLS--LDNQNIENL 474 Query: 502 IEKLKSAEEQITQLNDEIDAANKN-------MIKVKSNHKLKLKQMQKTIDN--FSKVSD 552 ++L + ++ + + + + ++K K + +Q+Q ++ K + Sbjct: 475 TQQLNNKNNELAEYQTQCEQQKQKHQLEVEELLKQIQQQKQEKEQIQADLEQKYMEKEKN 534 Query: 553 SNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVY------KKMIEME 606 E+ + E LS KV L ++ LQ + D + + ++ ++ Sbjct: 535 FQNELKQQQEREEELSTKVQVLIQQTNQLQQLINDSTNQAQVMRKLFLDPQNESAEADLP 594 Query: 607 NLAETRLKAISLLESQ-KFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLE 665 N KAI+L + K DL Q +Q+ E+ED +Q ++ ++ L Sbjct: 595 NQLMELNKAIALKFCKLKQDLEQNSKQIQEY--EIEDSKNSYNQQSLLIEQLQLTTIELN 652 Query: 666 EQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKL- 724 + + + E AL+ + ++ + E L + L + + + LQN +N DL + Sbjct: 653 QAKQKIDNLQSENALLQKQMQTNSEFL-NNLNQLTLQQNEKIQNLQNLEIQNKDLIQQSI 711 Query: 725 -EKMSAEKISE---LLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICR 780 EK +++SE + + N + Q K+Q + +I +++ I N+ S++S+ + Sbjct: 712 SEKQINQQLSEQNIIFDQQNQDLQIKLQA---LQIEILKKEDLINNLSSKISQLNQQN-- 766 Query: 781 LEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEY-------TIQEDELVNRLAVLMDH 833 +E + + E ++ ++ QE Q + ++Y T+Q L + L D Sbjct: 767 -QEQVIINEQLQFQIKESIHNTQELQQENQISKTQYDQQNENLTMQNSTLEKEIIQLKDQ 825 Query: 834 DRVVEKQLLEIEHENKELQKKNQILLEE-NQNLQISLSDMQQHYNALVEKANRTD----L 888 ++++Q+ + + KEL+ N + +E Q QI D Q V++ ++T L Sbjct: 826 ITILDEQVNNLNQKIKELEILNSLKQDEIQQQDQIQQQDQIQQ-QVQVQEQDQTQQYDQL 884 Query: 889 AESESTKYQTQLRDLESNLKR--ITHEHQTLIVQKKK--EIEDLEIEFNTQIESAIRDKK 944 + + Q Q +D + N + I +Q + +Q ++ + + + +E N+Q+ + K Sbjct: 885 QQQVQLQDQVQQKDNQDNKQNEIIQQTYQEIGIQTEQLEQQQVINLELNSQLAEPLEINK 944 Query: 945 VLNEKYEKNIEYVT-QLEAQ---LQEYKNNIENLNMNVEELNKMN-LELI-DKHVQKQQT 998 + K ++ IE +T QL Q LQ+ +N+I+ + + L K + ++L+ + Q Sbjct: 945 EQHSKLQQQIEELTIQLNQQTTALQQAQNDIDQMKIENTSLVKSHEMQLLREGEFTLQIE 1004 Query: 999 QSPDYTEQYINEINKLNALLK----QKDEEIIALNQKI---NNAQVSYMSMVSDY----E 1047 Q + EQ ++I +L +K Q +I L Q++ N+ + ++ Y E Sbjct: 1005 QLIEINEQKSSKIEELETQIKESQLQYQNDIQELQQQLFTENDEWLKEKEIIQQYIDQLE 1064 Query: 1048 SKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIP 1107 K + T +++ ++E+Q + KQ E LQI+ + K+ E K FE I Sbjct: 1065 HKGLELTNQIKVKDDEIQNIQKQNQQLSDQLEGLQIVNEKAQQLEKQCLENKQKFEQQID 1124 Query: 1108 KTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQ--EEEEFIQERSVLQEQSAKL- 1164 + I + + + LK Q E+EE I+E+ +L Sbjct: 1125 EINLKNILKNNDFIKQ-IQQLQQQSQDDQVKLLELKKQLEEKEESIKEKDGKHAIEIQLI 1183 Query: 1165 -NTELQECYTKIIQLETLNTELTGHDVVNQEQIN------QLKSKLEQLNTENDNLLSTV 1217 N + K ++ L E+ + V +Q N +K LEQ +EN + + Sbjct: 1184 TNNYVNRLKDKDDVIQNLQQEIQSYQQVELDQQNLIKFLENVKENLEQQKSENFEYIQEI 1243 Query: 1218 AELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQS 1277 I +Q+ +I +L + +E + QK HEL + + Y+Q L QS Sbjct: 1244 QLTNEKIIQQSEQQELQINQL---QVTIKELE-QKN-HELETEKINISNNYQQALIEAQS 1298 Query: 1278 --STQEETNKIV--TMEQVTSLQNKLQD 1301 TQ+ +N+I+ E+V L+ ++ D Sbjct: 1299 LNQTQDNSNEIIEKMQEEVVLLKCRIGD 1326 Score = 111 bits (268), Expect = 1e-22 Identities = 191/919 (20%), Positives = 392/919 (42%), Gaps = 109/919 (11%) Query: 702 DKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGI------DA 755 D D +N+ +N I E + L D +K + + LA++ + I +Q I D Sbjct: 99 DIADYLNQYKNDINEELLLQDCPDKKAKIHLKIHLAEVGEVDFDAINSQSSIVQEQTSDK 158 Query: 756 KIQERDLYIENIESELSKY----KSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQK 811 K + E ES + + L +S + + ++ + QLGS Q++ Sbjct: 159 KTGIFTPFKEAFESTKKYFGDSQSGQSPNLNKSFSKSQSNHPTVTDVSSQLGSPKQQQNS 218 Query: 812 AYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSD 871 S IQ D + L ++ +++ +EI+ +N +LQ++ Q + + L + L + Sbjct: 219 NMSNQ-IQLD--LQHLHEELNQQKIL---YMEIKDQNNKLQQEVQTEKVKKEALVLQLQE 272 Query: 872 MQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIED---L 928 ++ + +V++ ++ + + +Y+ QL ++S L++ +++ L KK ++ L Sbjct: 273 QRKQIDKMVDQ----NIYQEQICQYEQQLSQIQSQLRQAQKDNENLTQNYKKAMQKYNKL 328 Query: 929 EI---EFNT--------QIESAIRDKKVL--------NEKYEKNIEY---VTQLEAQLQE 966 I E NT ++E ++K L N+ +NI + +TQ QL + Sbjct: 329 SINSEEQNTSSLKQRLQELEEICKNKDQLYSVLERSNNDSQHRNINFENQITQQNQQLLQ 388 Query: 967 YKNNIENLNMNV----EELNKMNLELIDKHVQK---QQTQS------PDYTEQYINE--- 1010 KN ++ ++ + E LN +NL+L++ Q QQ + + ++Q I + Sbjct: 389 LKNKLDEKDILIDSQKESLNNLNLQLLNLQNQNCSLQQNEKIHNEKIDELSKQIIQQQEQ 448 Query: 1011 INKLNALLKQKDEEIIAL-NQKINNAQVSYMSMVSDYESKLAQFTTKLENMEE----EMQ 1065 IN+ + +K++ E+ ++L NQ I N +++ ++LA++ T+ E ++ E++ Sbjct: 449 INQQSIEIKKQCEDHLSLDNQNIENLT----QQLNNKNNELAEYQTQCEQQKQKHQLEVE 504 Query: 1066 RVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDA 1125 + KQ+ KQ E++Q + + + E KE E+ + +S+ ++ + Sbjct: 505 ELLKQIQQQKQEKEQIQA---DLEQKYME-KEKNFQNELKQQQEREEELSTKVQVLIQQT 560 Query: 1126 NNVDXXXXXXXXXXXXL-KVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTE 1184 N + + K+ + + + L Q +LN + + K+ Q N++ Sbjct: 561 NQLQQLINDSTNQAQVMRKLFLDPQNESAEADLPNQLMELNKAIALKFCKLKQDLEQNSK 620 Query: 1185 LTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLA 1244 + + +I K+ Q + + L T EL + +D E A L KQ Sbjct: 621 Q-----IQEYEIEDSKNSYNQQSLLIEQLQLTTIELNQA-KQKIDNLQSENALLQKQ--M 672 Query: 1245 QREADFQKTEHELRVQ----LSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQ 1300 Q ++F ++L +Q + ++ Q D +Q S E+ EQ + Q Sbjct: 673 QTNSEFLNNLNQLTLQQNEKIQNLQNLEIQNKDLIQQSISEKQINQQLSEQNIIFDQQNQ 732 Query: 1301 DKEEHLRNLQE---KYADVINQIEILRSEIED---EKVAFXXXXXXXXXXXXXXXXDLRT 1354 D + L+ LQ K D+IN + S++ E+V +L+ Sbjct: 733 DLQIKLQALQIEILKKEDLINNLSSKISQLNQQNQEQVIINEQLQFQIKESIHNTQELQQ 792 Query: 1355 ENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDS 1414 ENQ K +Q N+ +N+ L+K +VN+ K+ EL LK Sbjct: 793 ENQISKTQYDQQNENLTMQNSTLEKEIIQLKDQITILDEQVNNLNQKIKELEILNSLKQD 852 Query: 1415 EIYQK---------THEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLK 1465 EI Q+ + + + +++ ++QQ V+ + +++ + + I++ Sbjct: 853 EIQQQDQIQQQDQIQQQVQVQEQDQTQQYDQLQQQ-VQLQDQVQQKDNQDNKQNEIIQQT 911 Query: 1466 MHENANHYETMQKESEIERVKLIEELNVKITESVSLNK-QVAELNKALEEEVAKTNEMQT 1524 E E ++++ I ELN ++ E + +NK Q ++L + +EE + N+ T Sbjct: 912 YQEIGIQTEQLEQQQVINL-----ELNSQLAEPLEINKEQHSKLQQQIEELTIQLNQQTT 966 Query: 1525 ALENQEIEIVTLNDEITNL 1543 AL+ + +I + E T+L Sbjct: 967 ALQQAQNDIDQMKIENTSL 985 Score = 97.9 bits (233), Expect = 2e-18 Identities = 171/871 (19%), Positives = 354/871 (40%), Gaps = 64/871 (7%) Query: 212 EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDV-RISSLEEANKLLEAARFEISLE 270 E KQ+ E + + K EK+++ D+E K + + + + K + E+S + Sbjct: 493 EQQKQKHQLEVEELLKQIQQQKQEKEQIQADLEQKYMEKEKNFQNELKQQQEREEELSTK 552 Query: 271 HSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIEL 330 L Q+ Q + K ++P E E + L N K +L Sbjct: 553 VQVLIQQTNQLQQLINDSTNQAQVMRKLFLDPQ-NESAEADLPNQLMELNKAIALKFCKL 611 Query: 331 LEHLNCQIRQTNK-ELENKLATMGTESKAVSSPSKKGSPLISRK---SGRNTASKMKSPW 386 + L +Q + E+E+ + +S + L K + + + Sbjct: 612 KQDLEQNSKQIQEYEIEDSKNSYNQQSLLIEQLQLTTIELNQAKQKIDNLQSENALLQKQ 671 Query: 387 SQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKD 446 Q +SE LN + +NE + ++ NKDL+ + ISEK + Sbjct: 672 MQTNSEFLNNLNQLTLQQNEKIQNLQNLEIQNKDLIQQS--ISEKQ------INQQLSEQ 723 Query: 447 TLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLK 506 +I Q + Q I + + +N ++ QL Q+ N E +N + L ++K Sbjct: 724 NIIFDQQNQDLQIKLQALQIEILKKEDLINNLSSKISQLNQQ-NQEQVIIN-EQLQFQIK 781 Query: 507 SAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHH 566 + +L E + + N ++ ++K I ++ D +I L E++++ Sbjct: 782 ESIHNTQELQQENQISKTQYDQQNENLTMQNSTLEKEI---IQLKD---QITILDEQVNN 835 Query: 567 LSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDL 626 L+QK+ ELE Q + D ++ + D ++ ++++ +T+ + Q D Sbjct: 836 LNQKIKELEILNSLKQDEIQQQD--QIQQQDQIQQQVQVQEQDQTQQYDQLQQQVQLQDQ 893 Query: 627 VQEL--------HILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKEL 678 VQ+ I+QQ Y E+ QL+ QV + + L E ++ +L Sbjct: 894 VQQKDNQDNKQNEIIQQTYQEIG---IQTEQLEQQQVINLELNSQLAEPLEINKEQHSKL 950 Query: 679 ALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAK 738 IE L + Q ++ +ND + + K++N L + E L + Sbjct: 951 QQQIEELTIQLNQQTTALQQAQNDIDQM--KIENTSLVKSHEMQLLREGEFTLQIEQLIE 1008 Query: 739 INHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERK 798 IN ++ SKI+ ++ +I+E L +Y++ I L++ + D + Sbjct: 1009 INEQKSSKIEE---LETQIKESQL----------QYQNDIQELQQQLFTENDEWLKEKEI 1055 Query: 799 ADQLGSYLQEK-QKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQI 857 Q L+ K + ++ +++DE+ N + ++ + QL ++ N++ Q+ + Sbjct: 1056 IQQYIDQLEHKGLELTNQIKVKDDEIQN----IQKQNQQLSDQLEGLQIVNEKAQQLEKQ 1111 Query: 858 LLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTL 917 LE Q + + ++ N L + + + Q++ LE LK+ E + Sbjct: 1112 CLENKQKFEQQIDEINLK-NILKNNDFIKQIQQLQQQSQDDQVKLLE--LKKQLEEKEES 1168 Query: 918 IVQKK-KEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNM 976 I +K K ++++ N + + ++DK + + ++ I+ Q+E Q +EN+ Sbjct: 1169 IKEKDGKHAIEIQLITNNYV-NRLKDKDDVIQNLQQEIQSYQQVELDQQNLIKFLENVKE 1227 Query: 977 NVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIAL-NQKINNA 1035 N+E+ N E I + +Q + +EQ +IN+L +K+ +++ L +KIN + Sbjct: 1228 NLEQQKSENFEYI-QEIQLTNEKIIQQSEQQELQINQLQVTIKELEQKNHELETEKINIS 1286 Query: 1036 QVSYMSMVSDYESKLAQFTTK--LENMEEEM 1064 +++ Q + +E M+EE+ Sbjct: 1287 NNYQQALIEAQSLNQTQDNSNEIIEKMQEEV 1317 Score = 73.7 bits (173), Expect = 4e-11 Identities = 159/841 (18%), Positives = 363/841 (43%), Gaps = 62/841 (7%) Query: 152 KEKD--NALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXX 209 KEK+ N L Q + + + T + L ++ N+ Q+I N +T Sbjct: 531 KEKNFQNELKQQQEREEELSTKVQVLIQQTNQLQQLI---NDSTNQAQVMRKLFLDPQNE 587 Query: 210 XXE-DTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRIS--SLEEANKLLEAARFE 266 E D Q+ ++ + + K + ++ K I+ ++ S S + + L+E + Sbjct: 588 SAEADLPNQLMELNKAIALKFCKLKQDLEQNSKQIQEYEIEDSKNSYNQQSLLIEQLQLT 647 Query: 267 -ISLEHSKLA-QELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTEL 324 I L +K L+ + + ++ +I+ +LEI N + Sbjct: 648 TIELNQAKQKIDNLQSENALLQKQMQTNSEFLNNLNQLTLQQNEKIQNLQNLEIQNKDLI 707 Query: 325 TKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKS 384 + I + +N Q+ + N + + + + +A+ K LI+ S + + ++ Sbjct: 708 QQSISE-KQINQQLSEQNIIFDQQNQDLQIKLQALQIEILKKEDLINNLSSKISQLNQQN 766 Query: 385 PWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXG 444 + +E L + I+ + + E I D E + + T Sbjct: 767 QEQVIINEQLQFQIKESIHNTQELQQENQISKTQYDQ-QNENLTMQNSTLEKEIIQLKDQ 825 Query: 445 KDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVK-DLIE 503 L Q+ +Q+ E L + + + + Q+Q++Q++ + +D + D ++ Sbjct: 826 ITILDEQVNNLNQKIKELEILNSLKQDEIQQQDQIQQQDQIQQQVQVQEQDQTQQYDQLQ 885 Query: 504 KLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQM-QKTIDNFSKVSDSNKEIVRLTE 562 + ++Q+ Q +++ + N+ + + ++ +Q+ Q+ + N +++ E + + + Sbjct: 886 QQVQLQDQVQQKDNQDNKQNEIIQQTYQEIGIQTEQLEQQQVINL-ELNSQLAEPLEINK 944 Query: 563 ELHH-LSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLES 621 E H L Q++ EL +QL+ + + ++D+ + IE +L ++ + LL Sbjct: 945 EQHSKLQQQIEEL-----TIQLNQ-QTTALQQAQNDIDQMKIENTSLVKSH--EMQLLRE 996 Query: 622 QKFDLVQE--LHILQQKYDEVEDKLADI--SQLQSDQVCSEIKSVHLEEQIDALSASKKE 677 +F L E + I +QK ++E+ I SQLQ E++ E + L K+ Sbjct: 997 GEFTLQIEQLIEINEQKSSKIEELETQIKESQLQYQNDIQELQQQLFTENDEWLK-EKEI 1055 Query: 678 LALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLA 737 + I+ L+ +L IK K+D ++QN ++N L+D+LE + ++E Sbjct: 1056 IQQYIDQLEHKGLELTNQIKV----KDD---EIQNIQKQNQQLSDQLEGLQI--VNE--- 1103 Query: 738 KINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLER 797 K E+ ++ + + +I E +L +NI + + +I +L++ + + L++ Sbjct: 1104 KAQQLEKQCLENKQKFEQQIDEINL--KNILKN-NDFIKQIQQLQQQSQDDQVKLLELKK 1160 Query: 798 KADQLGSYLQEKQKAYS-EYTIQEDELVNRLAVLMDHDRVVEKQLLEIE-HENKELQKKN 855 + ++ ++EK ++ E + + VNRL D D V++ EI+ ++ EL ++N Sbjct: 1161 QLEEKEESIKEKDGKHAIEIQLITNNYVNRLK---DKDDVIQNLQQEIQSYQQVELDQQN 1217 Query: 856 QILLEEN--QNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHE 913 I EN +NL+ S+ ++ ++ N + +SE + + Q+ L+ +K + Sbjct: 1218 LIKFLENVKENLEQQKSENFEYIQE-IQLTNEKIIQQSE--QQELQINQLQVTIKELE-- 1272 Query: 914 HQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIEN 973 QK E+E +I + + A+ + + LN+ + + E + +++ ++ K I + Sbjct: 1273 ------QKNHELETEKINISNNYQQALIEAQSLNQTQDNSNEIIEKMQEEVVLLKCRIGD 1326 Query: 974 L 974 + Sbjct: 1327 M 1327 Score = 69.7 bits (163), Expect = 6e-10 Identities = 131/742 (17%), Positives = 308/742 (41%), Gaps = 62/742 (8%) Query: 887 DLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDL--EIEFNTQ-IESAIRDK 943 D +S +SN +T L K+++ ++ +I+ + Q + + + Sbjct: 179 DSQSGQSPNLNKSFSKSQSNHPTVTDVSSQLGSPKQQQNSNMSNQIQLDLQHLHEELNQQ 238 Query: 944 KVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDY 1003 K+L Y + + +L+ ++Q K E L + ++E K +++D+++ ++Q Sbjct: 239 KIL---YMEIKDQNNKLQQEVQTEKVKKEALVLQLQEQRKQIDKMVDQNIYQEQIC---- 291 Query: 1004 TEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSM-VSDYESKLAQFTTKLENMEE 1062 QY +++++ + L+Q ++ L Q A Y + ++ E + +L+ +EE Sbjct: 292 --QYEQQLSQIQSQLRQAQKDNENLTQNYKKAMQKYNKLSINSEEQNTSSLKQRLQELEE 349 Query: 1063 ------EMQRVSKQLLDSKQH-NEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIIS 1115 ++ V ++ + QH N + + +Q+ Q+ +LK ++ I + + + Sbjct: 350 ICKNKDQLYSVLERSNNDSQHRNINFENQITQQNQQLLQLKNKLDEKDILIDSQKESLNN 409 Query: 1116 STIEPMSDDANNVDXXXXXXXXXXXXLKVQE-EEEFIQERSVLQEQSAKLNTELQECYTK 1174 ++ ++ N K+ E ++ IQ++ + +QS ++ + ++ + Sbjct: 410 LNLQLLNLQNQNCSLQQNEKIHNE---KIDELSKQIIQQQEQINQQSIEIKKQCEDHLSL 466 Query: 1175 IIQ-LETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSS---ISSAVDQ 1230 Q +E L +L + E Q + + ++ E + LL + + + I + ++Q Sbjct: 467 DNQNIENLTQQLNNKNNELAEYQTQCEQQKQKHQLEVEELLKQIQQQKQEKEQIQADLEQ 526 Query: 1231 RGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEET--NKIVT 1288 + E + ++ L Q+ Q+ E EL ++ + QL + ST + K+ Sbjct: 527 KYMEKEKNFQNELKQQ----QEREEELSTKVQVLIQQTNQLQQLINDSTNQAQVMRKLFL 582 Query: 1289 MEQVTS----LQNKLQD--KEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXX 1342 Q S L N+L + K L+ + K N +I EIED K ++ Sbjct: 583 DPQNESAEADLPNQLMELNKAIALKFCKLKQDLEQNSKQIQEYEIEDSKNSYNQQSLLIE 642 Query: 1343 XXXXXXXXDLRTENQSYKQMQEQSIL--NINEENAQLKKSSXXXXXXXXXXXXRVNDAEA 1400 +L Q +Q ++ L + N++ + + + E Sbjct: 643 QLQLTTI-ELNQAKQKIDNLQSENALLQKQMQTNSEFLNNLNQLTLQQNEKIQNLQNLEI 701 Query: 1401 KVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQL-VEYEKR----------IE 1449 + +L Q + + +I Q+ E I Q+N + + Q L +E K+ I Sbjct: 702 QNKDLIQQ-SISEKQINQQLSEQNIIFDQQNQDLQIKLQALQIEILKKEDLINNLSSKIS 760 Query: 1450 DLTYEKESELAI---LRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVA 1506 L + + ++ I L+ ++ E+ ++ + +Q+E++I + + ++ ++ +L K++ Sbjct: 761 QLNQQNQEQVIINEQLQFQIKESIHNTQELQQENQISKTQYDQQNENLTMQNSTLEKEII 820 Query: 1507 ELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQ 1566 +L + + N + ++ EI DEI Q+ ++ +IQ+ V + Sbjct: 821 QLKDQITILDEQVNNLNQKIKELEILNSLKQDEIQQ-QDQIQ-QQDQIQQQVQVQEQDQT 878 Query: 1567 GRDEQLDNTMNKELLDAVPRAE 1588 + +QL + +L D V + + Sbjct: 879 QQYDQLQQQV--QLQDQVQQKD 898 >UniRef50_Q4RT41 Cluster: Chromosome 12 SCAF14999, whole genome shotgun sequence; n=4; Eumetazoa|Rep: Chromosome 12 SCAF14999, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1488 Score = 137 bits (331), Expect = 3e-30 Identities = 267/1364 (19%), Positives = 552/1364 (40%), Gaps = 106/1364 (7%) Query: 240 LKDIESKD-VRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQ 298 +K++E ++ V E+ ++ + E+ S++AQ E+ + Q Sbjct: 15 VKELEERETVLTQQTEDKDRETKEQMAEMVALRSQVAQNNEEMVTLKKQLEVVQSQGSDQ 74 Query: 299 S---IEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTE 355 +E SC+ ++ +E SL+ + +K L + L C + ++ E K + T Sbjct: 75 GAKVVELSCQLESGQQEVLSLQKSLAASKQEKEALDKELACLKQNLSESTEEKTKSAKTM 134 Query: 356 SKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQ 415 +A+ SKK S + T SQL+ ++K+ K LE ++ Sbjct: 135 QEALDQLSKKEEEYTSLTAESETLR------SQLAG------LERKL-KTAAEALEQHVK 181 Query: 416 SLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVG-TNTED 474 K D ++ K + +D + + +LE Q V N + Sbjct: 182 DKRKLETDMSEMM--KQSGDSSAQLTKMNQDLIEKERKLEDFQSQLAEEKNKVALLNEQA 239 Query: 475 VNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQ---LNDEIDAANKNMIKVKS 531 E + +LK+ E V DL EK++S E+ + + L +E+ A+ ++ + S Sbjct: 240 EQEKSHKDRELKE--TKETHQSQVNDLQEKIRSLEKAVKEGETLAEELKASQQSSVSQAS 297 Query: 532 N-HKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDS 590 H +++ +Q +D + S+K + L + V+EL+ K Q + DS Sbjct: 298 ELHAKEVELLQNQVDKLEQELSSSK------VKSEALEKSVSELQAYKEQAQCLSAELDS 351 Query: 591 GRMIESDVYKKMIEMENL-AETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADIS- 648 + ++ + + +E ++L E K + ++K L +EL +Q ++ +E +S Sbjct: 352 YK-LDVEHLSRNLEKQSLDLENMCKESDCVRAEKGKLEKELSEVQSRFSALETAHGALSG 410 Query: 649 QLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMN 708 Q + Q+ E S + EE + + S +E L E+L +++++ E N Sbjct: 411 QKEELQMVREELSKNQEELLAKMKCSDEER----NQLNKQLEKLREDLQEMQRQNE---N 463 Query: 709 KLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSK---IQTQFGIDAKIQERDLYIE 765 Q Q+ ++ T+ L+K +AE LL + +Q++ Q DA ER + Sbjct: 464 LKQINDQQKIE-TEDLQKQNAESNDSLLKQQEQLQQAEGKYRQLLHDYDAACHER----K 518 Query: 766 NIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVN 825 +E EL + +S++ +++ + D + ++ D + LQ K K+ + +++++L Sbjct: 519 RLEGELGESRSKLTCERDNVVLERDSARNAKKALDAKNAELQAKLKSLN---LEKEDLTL 575 Query: 826 RLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLS----DMQQHYNALVE 881 + L + K+ E+ E + + L + LQ LS D++ E Sbjct: 576 KNTQLQALTEALTKEKEEMSSEISTAVRDKKSLEAAKEELQNKLSATKKDLESSIRECEE 635 Query: 882 -KANRTDLAES-ESTKYQTQLRDLESNLKRITHEHQTLIVQKK--KEIEDLEIEFNTQIE 937 +A++ LA+ E K +Q+ D E + + + + L Q++ E E+L+ E E Sbjct: 636 LRASKVSLAQMLEEFKKTSQVTDSE-RMNLLQQKEELLASQRRACSEREELQGEIGEVQE 694 Query: 938 SAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQ 997 + L+E K+ + ++ EA+ + + M + K + L + +++Q+ Sbjct: 695 KLRAATEQLSELRGKHTDALSSFEAEKKAFSLQTSEAEMALHVSRKEKMSL-ESALEQQK 753 Query: 998 TQSPDYTEQYINEINKLNALLKQKDE-----EIIALNQKINNAQVSYMSMV-SDYESKLA 1051 E+ N+L + +KD + +A + + Q+ S +D+ + + Sbjct: 754 MGYECLLEEKGELENRLTDTVSEKDALSCECDRLARDLQTLKDQLDRSSRENADFVQEKS 813 Query: 1052 QFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEG 1111 T KLE + ++ LQ +++ ++ L++ K E K + Sbjct: 814 DLTAKLEESVRSKAAADADVSSLEKEKATLQGELQKHKSDLEALEKNKRELEQEREKLKT 873 Query: 1112 MIISST------IEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLN 1165 ST I+ + +D + ++ +E++E ++E L+ Q+ L+ Sbjct: 874 EFKESTSELAQQIDSLKNDCQRLQSLRTESDAGLQAVQ-KEKQEMLEESQELRRQAEALS 932 Query: 1166 TELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSIS 1225 + + T++ + T+ H Q+ +L+ ++ Q+ EN L S + L + Sbjct: 933 EDKRLLETRLQAESSERTKAASHQDQLARQLEELQKEMVQVTQENQELSSNLRNLDEQMR 992 Query: 1226 SAVDQRGFEIAELWKQHLAQREADF-QKTE---------HELRVQLSAFESKYEQLLDSV 1275 ++V R E K+ L QRE D Q+ E E Q+++ ++ E LLD Sbjct: 993 TSVMDR-----EALKEQLKQREQDIGQRAEEKEGLLVQLQEREKQVASLTTERESLLDGR 1047 Query: 1276 QSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDE---KV 1332 + + + E + ++ + + E R LQEK + ++ + ++E++ V Sbjct: 1048 SKLEMDVSALRSSQESWLAERSTVLAEVEESRCLQEKLEADMKVLQTAKEQLEEQHKSAV 1107 Query: 1333 AFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXX 1392 DL + ++ + ++++ I + QLK +S Sbjct: 1108 EEISASALAKAESRSSIADLTAQKKTLQAERDEAAQQIRQLQIQLKNASAKQVEMKELRA 1167 Query: 1393 XRV---NDAEAKVLELTHQLELKDS---EIYQ-KTHE--YTITLTQRNDEFENVRQQLVE 1443 D A +L + + S EI KT + T +L DE + + Q+L Sbjct: 1168 ENSKYHEDLSASKEQLCTETQRTKSLCQEIEDLKTADSAKTQSLQALKDENDKLTQELDI 1227 Query: 1444 YEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEE---LNVKITESVS 1500 +LT K++ LR + E N E QK + R + E L + ++ + Sbjct: 1228 AHGGQSELTKVKQAYFLKLRKENSELQNQLEESQKSASTFREQSDGEKAALQQSMRKNSA 1287 Query: 1501 LNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQ 1544 L + +L + L EVA+ + A+ + + + L + L+ Sbjct: 1288 LIAEKEQLVQKLRSEVAELHSRGAAVPSLQGAVQALEQDKKELE 1331 Score = 89.0 bits (211), Expect = 9e-16 Identities = 153/793 (19%), Positives = 318/793 (40%), Gaps = 50/793 (6%) Query: 765 ENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELV 824 E+ + E + + + L +A + +L+++ + + S ++ E + Q E Sbjct: 30 EDKDRETKEQMAEMVALRSQVAQNNEEMVTLKKQLEVVQSQGSDQGAKVVELSCQL-ESG 88 Query: 825 NRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKAN 884 + + + KQ E E +KEL Q L E + S MQ+ + L +K Sbjct: 89 QQEVLSLQKSLAASKQ--EKEALDKELACLKQNLSESTEEKTKSAKTMQEALDQLSKKEE 146 Query: 885 RTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKK 944 +ES ++QL LE LK + + K+K D+ +S+ + K Sbjct: 147 EYTSLTAESETLRSQLAGLERKLKTAAEALEQHVKDKRKLETDMSEMMKQSGDSSAQLTK 206 Query: 945 VLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYT 1004 + + EK + + ++QL E KN + LN E+ H ++ ++ + Sbjct: 207 MNQDLIEKERK-LEDFQSQLAEEKNKVALLNEQAEQEKS--------HKDRELKETKETH 257 Query: 1005 EQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEM 1064 + +N++ + L++ +E L +++ +Q S +S S+ +K ++E ++ ++ Sbjct: 258 QSQVNDLQEKIRSLEKAVKEGETLAEELKASQQSSVSQASELHAK------EVELLQNQV 311 Query: 1065 QRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDD 1124 ++ ++L SK +E L+ V E KE + L+ E++ K + +S +E S D Sbjct: 312 DKLEQELSSSKVKSEALEKSVSELQ-AYKEQAQC-LSAELDSYKLDVEHLSRNLEKQSLD 369 Query: 1125 ANNVDXXXXXXXXXXXXLKVQEEEEFIQER-SVLQEQSAKLNTELQECYTKIIQLETLNT 1183 N+ K+++E +Q R S L+ L+ + +E +L Sbjct: 370 LENMCKESDCVRAEKG--KLEKELSEVQSRFSALETAHGALSGQKEELQMVREELSKNQE 427 Query: 1184 ELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHL 1243 EL + E+ NQL +LE+L + L + ++ DQ+ E +L KQ+ Sbjct: 428 ELLAKMKCSDEERNQLNKQLEKLRED----LQEMQRQNENLKQINDQQKIETEDLQKQNA 483 Query: 1244 AQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKE 1303 ++ ++ E QL E KY QLL ++ E ++ ++KL + Sbjct: 484 ESNDSLLKQQE-----QLQQAEGKYRQLLHDYDAACHERKR---LEGELGESRSKLTCER 535 Query: 1304 EHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQ 1363 +++ ++ + ++ +E++ A L+ ++ + + Sbjct: 536 DNVVLERDSARNAKKALDAKNAELQ----AKLKSLNLEKEDLTLKNTQLQALTEALTKEK 591 Query: 1364 EQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEY 1423 E+ I+ K D E+ + E +L + Q E+ Sbjct: 592 EEMSSEISTAVRDKKSLEAAKEELQNKLSATKKDLESSIREC-EELRASKVSLAQMLEEF 650 Query: 1424 TITLTQRNDEFENVRQQ---LVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKES 1480 T + E N+ QQ L+ ++R E + E+ ++ K+ ++ S Sbjct: 651 KKTSQVTDSERMNLLQQKEELLASQRRACSEREELQGEIGEVQEKLRA------ATEQLS 704 Query: 1481 EIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEI 1540 E+ R K + L+ E + + Q +E AL + +++ALE Q++ L +E Sbjct: 705 EL-RGKHTDALSSFEAEKKAFSLQTSEAEMALHVSRKEKMSLESALEQQKMGYECLLEEK 763 Query: 1541 TNLQNMVRASSSK 1553 L+N + + S+ Sbjct: 764 GELENRLTDTVSE 776 Score = 85.4 bits (202), Expect = 1e-14 Identities = 166/898 (18%), Positives = 359/898 (39%), Gaps = 49/898 (5%) Query: 228 MEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXX 287 +E E + + +L + ++ + S A K L+A E+ + L E E Sbjct: 520 LEGELGESRSKLTCERDNVVLERDSARNAKKALDAKNAELQAKLKSLNLEKEDLTLKNTQ 579 Query: 288 XXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELL-EHLNCQIRQTNKELE 346 L K+ E S E T + +K SLE A EL K+ + L IR+ + Sbjct: 580 LQALTEALTKEKEEMSSEISTAVRDKKSLEAAK-EELQNKLSATKKDLESSIRECEELRA 638 Query: 347 NK--LATMGTESKAVSSPSKKGSPLISRKSGRNTASKMK--SPWSQLSSETLNQDTDKKI 402 +K LA M E K S + + ++ AS+ + S +L E + Sbjct: 639 SKVSLAQMLEEFKKTSQVTDSERMNLLQQKEELLASQRRACSEREELQGEIGEVQEKLRA 698 Query: 403 NKNEIAKLE-MVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHME 461 ++++L +L+ +K+ T K+ + + LE Q+ Sbjct: 699 ATEQLSELRGKHTDALSSFEAEKK--AFSLQTSEAEMALHVSRKEKMSLESALEQQKMGY 756 Query: 462 GPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDV-NVKDLIEKLKSAEEQITQLNDEID 520 L G + + ++ L E + +D+ +KD +++ Q ++ Sbjct: 757 ECLLEEKGELENRLTDTVSEKDALSCECDRLARDLQTLKDQLDRSSRENADFVQEKSDLT 816 Query: 521 AANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGN 580 A + ++ K+ + ++K + + E+ + +L L + ELE+E+ Sbjct: 817 AKLEESVRSKAAADADVSSLEK------EKATLQGELQKHKSDLEALEKNKRELEQEREK 870 Query: 581 LQLHLVDYDSGRMIESDVYKKMIE-MENLAETRLKAISLLESQKFDLVQELHILQQKYDE 639 L+ + S + D K + +++L + ++ +K ++++E L+++ + Sbjct: 871 LKTEFKESTSELAQQIDSLKNDCQRLQSLRTESDAGLQAVQKEKQEMLEESQELRRQAEA 930 Query: 640 V-EDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKD 698 + EDK ++LQ++ + H ++ L +KE+ V + + ++L +++ Sbjct: 931 LSEDKRLLETRLQAESSERTKAASHQDQLARQLEELQKEMVQVTQ----ENQELSSNLRN 986 Query: 699 L-ENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKI 757 L E + +M++ ++E + ++ AE+ LL ++ E+ ++ + Sbjct: 987 LDEQMRTSVMDR--EALKEQLKQREQDIGQRAEEKEGLLVQLQEREKQVASLTTERESLL 1044 Query: 758 QERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYT 817 R ++ + S +S + +A +E+ R L+ K + LQ ++ E Sbjct: 1045 DGRSKLEMDVSALRSSQESWLAERSTVLAEVEESR-CLQEKLEADMKVLQTAKEQLEEQH 1103 Query: 818 IQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYN 877 E ++ A+ R + ++ + K LQ + ++ + LQI L N Sbjct: 1104 KSAVEEISASALAKAESR---SSIADLTAQKKTLQAERDEAAQQIRQLQIQLK------N 1154 Query: 878 ALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIE 937 A ++ +L +E++KY L + L T ++L +EIEDL+ + + + Sbjct: 1155 ASAKQVEMKEL-RAENSKYHEDLSASKEQLCTETQRTKSLC----QEIEDLKTADSAKTQ 1209 Query: 938 SAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMN-LELIDKHVQKQ 996 S ++ K N+K + ++ +++L + K L + E N LE K Sbjct: 1210 S-LQALKDENDKLTQELDIAHGGQSELTKVK-QAYFLKLRKENSELQNQLEESQKSASTF 1267 Query: 997 QTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTK 1056 + QS + K +AL+ +K++ + L ++ S + V + + Sbjct: 1268 REQSDGEKAALQQSMRKNSALIAEKEQLVQKLRSEVAELH-SRGAAVPSLQGAVQALEQD 1326 Query: 1057 LENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMII 1114 + +EE QR+ ++L +K + + D + +L+E K T E I +I+ Sbjct: 1327 KKELEERAQRLEEELAAAKN-----TLSLPSGDAVLDQLREDKETAESQIQFLNSVIV 1379 Score = 55.6 bits (128), Expect = 1e-05 Identities = 92/508 (18%), Positives = 194/508 (38%), Gaps = 21/508 (4%) Query: 1060 MEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIE 1119 ME+ + ++ L K+ E +L ++ +D+ +E KE EM +++ + + Sbjct: 1 MEDVLGKLHAAELRVKELEERETVLTQQTEDKDRETKEQMA--EMVALRSQVAQNNEEMV 58 Query: 1120 PMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLE 1179 + V L Q E QE LQ+ A E + ++ L+ Sbjct: 59 TLKKQLEVVQSQGSDQGAKVVELSCQLESGQ-QEVLSLQKSLAASKQEKEALDKELACLK 117 Query: 1180 TLNTELTGHDVVN----QEQINQLKSKLEQ---LNTENDNLLSTVAELRSSISSAVDQRG 1232 +E T + QE ++QL K E+ L E++ L S +A L + +A + Sbjct: 118 QNLSESTEEKTKSAKTMQEALDQLSKKEEEYTSLTAESETLRSQLAGLERKLKTAAEALE 177 Query: 1233 FEIAELWKQHLAQREADFQKTEHELRVQLSAFES---KYEQLLDSVQSSTQEETNKIVTM 1289 + + K+ L ++ K + QL+ + E+ L+ QS EE NK+ + Sbjct: 178 QHVKD--KRKLETDMSEMMKQSGDSSAQLTKMNQDLIEKERKLEDFQSQLAEEKNKVALL 235 Query: 1290 EQVTSLQNKLQDKEEHLRNLQEKYADVINQI-EILRSEIEDEKVAFXXXXXXXXXXXXXX 1348 + + +D+E L+ +E + +N + E +RS + K Sbjct: 236 NEQAEQEKSHKDRE--LKETKETHQSQVNDLQEKIRSLEKAVKEGETLAEELKASQQSSV 293 Query: 1349 XXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQ 1408 + + +Q Q + + +E + K S A+ EL Sbjct: 294 SQASELHAKEVELLQNQ-VDKLEQELSSSKVKSEALEKSVSELQAYKEQAQCLSAELD-S 351 Query: 1409 LELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHE 1468 +L + + + ++ L E + VR + + EK + ++ + S L + Sbjct: 352 YKLDVEHLSRNLEKQSLDLENMCKESDCVRAEKGKLEKELSEVQ-SRFSALETAHGALSG 410 Query: 1469 NANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALEN 1528 + +++E + +L+ ++ E LNKQ+ +L + L+E + ++ + Sbjct: 411 QKEELQMVREELSKNQEELLAKMKCSDEERNQLNKQLEKLREDLQEMQRQNENLKQINDQ 470 Query: 1529 QEIEIVTLNDEITNLQNMVRASSSKIQK 1556 Q+IE L + + + ++Q+ Sbjct: 471 QKIETEDLQKQNAESNDSLLKQQEQLQQ 498 Score = 54.0 bits (124), Expect = 3e-05 Identities = 116/576 (20%), Positives = 228/576 (39%), Gaps = 43/576 (7%) Query: 174 DLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWK 233 DL+ K ++ + + K T D ++ + E+ ++A K Sbjct: 853 DLEALEKNKRELEQEREKLKTEFKESTSELAQQIDSLKNDCQRLQSLRTESDAGLQAVQK 912 Query: 234 DEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXX 293 EKQ +L++ + + +L E +LLE S E +K A +Q Sbjct: 913 -EKQEMLEESQELRRQAEALSEDKRLLETRLQAESSERTKAASHQDQLARQLEELQKEMV 971 Query: 294 XLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMG 353 + +++ E S + ++E+ + + L ++++ E I Q +E E L + Sbjct: 972 QVTQENQELSSNLR-NLDEQMRTSVMDREALKEQLKQREQ---DIGQRAEEKEGLLVQLQ 1027 Query: 354 TESKAVSS-PSKKGSPLISRKSGRNTASKMKS---PWSQLSSETLNQDTDKKINKNEIAK 409 K V+S +++ S L R S ++S W S L + + + + ++ Sbjct: 1028 EREKQVASLTTERESLLDGRSKLEMDVSALRSSQESWLAERSTVLAEVEESRCLQEKLEA 1087 Query: 410 LEMVIQSLNKDLVDK-EYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHV 468 V+Q+ + L ++ + + E L AQ + + E I Sbjct: 1088 DMKVLQTAKEQLEEQHKSAVEEISASALAKAESRSSIADLTAQKKTLQAERDEAAQQIR- 1146 Query: 469 GTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIK 528 + N AK Q ++K E++ N K E L +++EQ+ + + + Sbjct: 1147 QLQIQLKNASAK-QVEMK-----ELRAENSK-YHEDLSASKEQLCTETQRTKSLCQEIED 1199 Query: 529 VKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQK-VAELEEEKGNLQLHLVD 587 +K+ K + +Q D K++ EL + Q +L +E LQ L + Sbjct: 1200 LKTADSAKTQSLQALKDENDKLTQELDIAHGGQSELTKVKQAYFLKLRKENSELQNQLEE 1259 Query: 588 YDSGRMIESDVYKKMIEMENLA-ETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLAD 646 + +++ + E A + ++ S L ++K LVQ+ L+ + E+ + A Sbjct: 1260 SQK----SASTFREQSDGEKAALQQSMRKNSALIAEKEQLVQK---LRSEVAELHSRGAA 1312 Query: 647 ISQLQSDQVCSEIKSVHLEEQI----DALSASKKELAL-----VIENLKLDKEQLYGTIK 697 + LQ E LEE+ + L+A+K L+L V++ L+ DKE I+ Sbjct: 1313 VPSLQGAVQALEQDKKELEERAQRLEEELAAAKNTLSLPSGDAVLDQLREDKETAESQIQ 1372 Query: 698 DLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKIS 733 L + D+ K N +L +KLEK++A ++ Sbjct: 1373 FLNSVIVDLQRK-------NEELKEKLEKVAAAALN 1401 >UniRef50_A0DQH1 Cluster: Chromosome undetermined scaffold_6, whole genome shotgun sequence; n=4; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_6, whole genome shotgun sequence - Paramecium tetraurelia Length = 1075 Score = 137 bits (331), Expect = 3e-30 Identities = 217/1058 (20%), Positives = 462/1058 (43%), Gaps = 93/1058 (8%) Query: 546 NFSKVSDSNK--EIVRLTEELHHLSQKVAELE---EEKGNLQLHLV-DYDSGRMIESDVY 599 N+ K D + E+ + ++ L ++A+ E E K LQ ++ + + + D Sbjct: 54 NYDKEVDESARDELEQWKKKYFSLEARLAKYEIDNEIKDELQSRILGSQEDVKKFQIDFT 113 Query: 600 KKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEI 659 K +++N K I +E+QK L Q++ + + K V ++ ISQL Q C E Sbjct: 114 KAQADLDNQKSEMNKLI--IENQKL-LNQQVEVERLK-KLVAEREDTISQLL--QKCKEY 167 Query: 660 KSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKD--LENDKEDIMNKLQNYIQEN 717 +EQ L A ++ L + N KE + T K +END NK Q I E Sbjct: 168 -----QEQFQELEAFQQALQ-DMHNQNQGKELMIETWKQKYIEND-----NKKQKEIDEL 216 Query: 718 MDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFG-IDAKIQERDLYIENIESELSKYKS 776 + + + + + E Q++++ Q + A +++ D + + +++ Sbjct: 217 KSKLAEFNPAEVQNLKDQFQRERQESQNQLKKQQSDLAAALKQLDQWKIKYNNLDLQHQQ 276 Query: 777 RICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRV 836 +ESIA +E + + Q+ ++KQK E + +L ++ + DR+ Sbjct: 277 LSSAQKESIARVETLTQEQNKLSTQIHQLNEDKQKLQIELEQTKGQLKLHQGLIGELDRI 336 Query: 837 VEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKY 896 K+LL ++ ELQ+ +L+++Q I L++ + + L +K L + E+ + Sbjct: 337 --KKLLS--DKSAELQQ----MLQQSQQKDIDLNNAELTISELNQKIKSLSLLQQENQRL 388 Query: 897 QTQLRDLESNLKRITHEHQTLI--VQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNI 954 Q ++ + +++ E+ L+ + K K +E + + +++ + + L + ++ Sbjct: 389 QHEIDESHRENEKLAQENSQLLKDIDKFKLLEQEKQQLESKVSMLASEIERLKVQLKQKN 448 Query: 955 EYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKL 1014 E + + Q ++ KN E L +E+L N +L+ + QK + + EQ + E+N L Sbjct: 449 EKILE---QQEDLKNLQEQLG-EIEQLENQNQQLLKELEQKDKII--EELEQKLQELNVL 502 Query: 1015 NALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQ--RVSKQLL 1072 L + +I L K+ A +S S Y + Q T +L+N EE++ + K+ L Sbjct: 503 EQKLADANNKIYDLENKV--AMLSAESQRLRYLND--QKTEQLKNAEEQLSDLNILKEKL 558 Query: 1073 DSKQHNEELQILVREQ-DDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXX 1131 Q+ + Q V + D++++L+ NI + + + + + +N + Sbjct: 559 SQLQNKYDAQQQVNQNYQDELEKLRGQSNQANTNIAELKRQLEEQKAQDIIHKQSNSESV 618 Query: 1132 XXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQL-ETLNTELT--GH 1188 L Q+ + + E ++ E+ L +LQ T + Q + LN + Sbjct: 619 IAELQQQLSSL--QQSYKKVSESNLANEEDPTL--DLQNRLTLLKQENQRLNQTIQQKNQ 674 Query: 1189 DVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQ-----RGFEIAELWKQHL 1243 +V+N +Q NQ L+Q E D+L + EL S + +Q +G + E Q Sbjct: 675 EVLNHQQQNQ---NLQQELLELDSLKVQIKELHESNTVLQEQLQNEAKGRQELEQRIQQT 731 Query: 1244 AQREADFQKTEHELRVQLSAFESKYEQL--LDSVQSSTQEETNKIVTME----QVTSLQN 1297 + D Q L + + K +++ +D ++ QE ++ M+ ++ SL++ Sbjct: 732 ESEKYDLQSKCAMLSTHIEGMKYKLDKMENVDDLKKRIQELEGQLAEMQALELEIESLKD 791 Query: 1298 KLQDKEEHLRNLQEKYADV---INQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRT 1354 ++ + E+ L+ ++K+ + Q+++ + ++E++ ++ Sbjct: 792 RIAELEKELKLWKQKHESLDQSYQQLQMTKEQMENKLAMLSSEIERLKVLNKKKQDEIDQ 851 Query: 1355 ENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTH------Q 1408 +NQ ++ +Q + +++ + + + +++D + K+ E+TH + Sbjct: 852 QNQELIKL-DQEMNDLHNQLEDINELKTQLGSLENQLQQQIDDNQDKLNEITHLKQQVAE 910 Query: 1409 LE--LKDSEIYQKTHEYTITLTQRNDEF-ENVRQQLVEYEKRI---EDLTYEKESELAIL 1462 +E L + E Q + T +Q DE + +Q+L + E +I ED+ Y+ E ++A+L Sbjct: 911 IEGLLVNQEDLQNQIKKLETESQSKDEIIDQFKQKLTQLESKIAELEDIKYKYEDKMALL 970 Query: 1463 RLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEE---EVAKT 1519 YE K+ E + +L +++ + +++V EL K L + E +K Sbjct: 971 ----SSEVKRYEFKAKKLEDKSNELTTQVDHLTADLNEADQKVIELEKDLGQWKFEYSKL 1026 Query: 1520 NEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKH 1557 N +Q ++ +V EI L++ V + ++ H Sbjct: 1027 NSLQYKIDEYSFLLVVSFAEIEALRSQVTTLNEQLDGH 1064 Score = 127 bits (306), Expect = 3e-27 Identities = 178/876 (20%), Positives = 396/876 (45%), Gaps = 68/876 (7%) Query: 372 RKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEK 431 ++ + + +++K S L++ L Q KI N + + S K+ + + ++++ Sbjct: 236 QRERQESQNQLKKQQSDLAA-ALKQLDQWKIKYNNLDLQHQQLSSAQKESIARVETLTQE 294 Query: 432 DTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELND 491 +D Q++LE + G +H G E ++ I K+ EL Sbjct: 295 QNKLSTQIHQL-NEDKQKLQIELEQTK---GQLKLHQGLIGE-LDRIKKLLSDKSAELQQ 349 Query: 492 EIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVS 551 ++ KD+ L +AE I++LN +I + + + + N +L+ + + +N K++ Sbjct: 350 MLQQSQQKDI--DLNNAELTISELNQKIKSLS---LLQQENQRLQHEIDESHREN-EKLA 403 Query: 552 DSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESD-VYKKMIEMENLAE 610 N ++++ ++ L Q+ +LE + L + +++ + ++ +++NL E Sbjct: 404 QENSQLLKDIDKFKLLEQEKQQLESKVSMLASEIERLKVQLKQKNEKILEQQEDLKNLQE 463 Query: 611 TRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDA 670 +L I LE+Q L++EL + +E+E KL +++ L+ + K LE ++ Sbjct: 464 -QLGEIEQLENQNQQLLKELEQKDKIIEELEQKLQELNVLEQKLADANNKIYDLENKVAM 522 Query: 671 LSASKKELALV----IENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEK 726 LSA + L + E LK +EQL + L+ + NK Q N + D+LEK Sbjct: 523 LSAESQRLRYLNDQKTEQLKNAEEQL-SDLNILKEKLSQLQNKYDAQQQVNQNYQDELEK 581 Query: 727 MSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEES-I 785 + + + Q + Q I K + I ++ +LS + ++ ES + Sbjct: 582 LRGQSNQANTNIAELKRQLEEQKAQDIIHKQSNSESVIAELQQQLSSLQQSYKKVSESNL 641 Query: 786 AVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIE 845 A ED L+ + L QE Q+ + E++N ++ ++++LLE++ Sbjct: 642 ANEEDPTLDLQNRLTLL---KQENQRLNQTIQQKNQEVLNH----QQQNQNLQQELLELD 694 Query: 846 H---ENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRD 902 + KEL + N +L E+ QN +++Q + ++ES KY D Sbjct: 695 SLKVQIKELHESNTVLQEQLQNEAKGRQELEQR------------IQQTESEKY-----D 737 Query: 903 LESNLKRI-TH-EHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQL 960 L+S + TH E + K + ++DL+ ++E + + + L + E + + +L Sbjct: 738 LQSKCAMLSTHIEGMKYKLDKMENVDDLKKRIQ-ELEGQLAEMQALELEIESLKDRIAEL 796 Query: 961 EAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQ 1020 E +L+ +K E+L+ + ++L +M E ++ + ++ + +N+ K + Q Sbjct: 797 EKELKLWKQKHESLDQSYQQL-QMTKEQMENKLAMLSSEIERL--KVLNK--KKQDEIDQ 851 Query: 1021 KDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEE 1080 +++E+I L+Q++N+ + + +++ +++L +L+ ++ Q ++ KQ E Sbjct: 852 QNQELIKLDQEMNDLH-NQLEDINELKTQLGSLENQLQQQIDDNQDKLNEITHLKQQVAE 910 Query: 1081 LQ-ILVREQD--DQIKELKETKLTFEMNIPKTEGMI--ISSTIEPMSDDANNVDXXXXXX 1135 ++ +LV ++D +QIK+L+ + + I + + + + S I + D + Sbjct: 911 IEGLLVNQEDLQNQIKKLETESQSKDEIIDQFKQKLTQLESKIAELEDIKYKYEDKMALL 970 Query: 1136 XXXXXXLKVQEEEEFIQERS-VLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQE 1194 + + ++ ++++S L Q L +L E K+I+LE + G Sbjct: 971 SSEVKRYEFKAKK--LEDKSNELTTQVDHLTADLNEADQKVIELE----KDLGQWKFEYS 1024 Query: 1195 QINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQ 1230 ++N L+ K+++ + + + LRS +++ +Q Sbjct: 1025 KLNSLQYKIDEYSFLLVVSFAEIEALRSQVTTLNEQ 1060 Score = 95.1 bits (226), Expect = 1e-17 Identities = 184/889 (20%), Positives = 373/889 (41%), Gaps = 58/889 (6%) Query: 698 DLENDKEDIMNKLQNYIQENMDLTDKLEK--MSAEKISELLAKI--NHEEQSKIQTQF-- 751 D E D E ++L+ + ++ L +L K + E EL ++I + E+ K Q F Sbjct: 56 DKEVD-ESARDELEQWKKKYFSLEARLAKYEIDNEIKDELQSRILGSQEDVKKFQIDFTK 114 Query: 752 ---GIDAKIQERD-LYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQ 807 +D + E + L IEN +L + + RL++ +A ED L +K + Q Sbjct: 115 AQADLDNQKSEMNKLIIEN--QKLLNQQVEVERLKKLVAEREDTISQLLQKCKEYQEQFQ 172 Query: 808 EKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQI 867 E + A+ + +Q+ N+ LM + +K + + KE+ + L E N Sbjct: 173 ELE-AFQQ-ALQDMHNQNQGKELMI-ETWKQKYIENDNKKQKEIDELKSKLAEFNPAEVQ 229 Query: 868 SLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIED 927 +L D Q E N+ +S+ QL + + +HQ L +K+ I Sbjct: 230 NLKDQFQRERQ--ESQNQLKKQQSDLAAALKQLDQWKIKYNNLDLQHQQLSSAQKESIAR 287 Query: 928 LEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLE 987 +E Q + + + ++ +K + IE + Q + QL+ ++ I L+ + L+ + E Sbjct: 288 VETLTQEQNKLSTQIHQLNEDKQKLQIE-LEQTKGQLKLHQGLIGELDRIKKLLSDKSAE 346 Query: 988 LIDKHVQKQQTQSP-DYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDY 1046 L Q QQ + E I+E+N+ L +E L +I+ + + + Sbjct: 347 LQQMLQQSQQKDIDLNNAELTISELNQKIKSLSLLQQENQRLQHEIDESHRENEKLAQE- 405 Query: 1047 ESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNI 1106 S+L + K + +E+E Q++ ++ E L++ +++++++I E +E + + Sbjct: 406 NSQLLKDIDKFKLLEQEKQQLESKVSMLASEIERLKVQLKQKNEKILEQQEDLKNLQEQL 465 Query: 1107 PKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNT 1166 + E + + + + + D ++E E+ +QE +VL+++ A N Sbjct: 466 GEIEQL--ENQNQQLLKELEQKDKI------------IEELEQKLQELNVLEQKLADANN 511 Query: 1167 ELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISS 1226 ++ + K+ L + L +N ++ QLK+ EQL+ N L +++L++ + Sbjct: 512 KIYDLENKVAMLSAESQRLR---YLNDQKTEQLKNAEEQLSDLNI-LKEKLSQLQNKYDA 567 Query: 1227 AVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKI 1286 EL K +A+ E L+ QL E K + ++ QS+++ ++ Sbjct: 568 QQQVNQNYQDELEKLRGQSNQANTNIAE--LKRQLE--EQKAQDIIHK-QSNSESVIAEL 622 Query: 1287 VTMEQVTSLQNKLQD-KEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXX 1345 +Q++SLQ + E +L N ++ D+ N++ +L+ E + Sbjct: 623 --QQQLSSLQQSYKKVSESNLANEEDPTLDLQNRLTLLKQENQRLNQTIQQKNQEVLNHQ 680 Query: 1346 XXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLEL 1405 +L+ E ++ Q I ++E N L++ R+ E++ +L Sbjct: 681 QQNQ-NLQQELLELDSLKVQ-IKELHESNTVLQEQLQNEAKGRQELEQRIQQTESEKYDL 738 Query: 1406 THQLELKDSEIYQKTH-----EYTITLTQRNDEFEN--VRQQLVEYE-KRIEDLTYEKES 1457 + + + I + E L +R E E Q +E E + ++D E E Sbjct: 739 QSKCAMLSTHIEGMKYKLDKMENVDDLKKRIQELEGQLAEMQALELEIESLKDRIAELEK 798 Query: 1458 ELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVA 1517 EL + + K Y+ +Q E KL L+ +I LNK+ + +E+ Sbjct: 799 ELKLWKQKHESLDQSYQQLQMTKEQMENKLAM-LSSEIERLKVLNKKKQDEIDQQNQELI 857 Query: 1518 KTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQ 1566 K ++ L NQ +I L ++ +L+N ++ Q ++ + KQ Sbjct: 858 KLDQEMNDLHNQLEDINELKTQLGSLENQLQQQIDDNQDKLNEITHLKQ 906 Score = 95.1 bits (226), Expect = 1e-17 Identities = 164/791 (20%), Positives = 335/791 (42%), Gaps = 72/791 (9%) Query: 843 EIEHENK-ELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLR 901 EI++E K ELQ + E+ + QI + Q + + N+ + E+ K Q Sbjct: 85 EIDNEIKDELQSRILGSQEDVKKFQIDFTKAQADLDNQKSEMNKLII---ENQKLLNQQV 141 Query: 902 DLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLE 961 ++E LK++ E + I Q ++ ++ + +F ++E+ ++ L + + +N +E Sbjct: 142 EVE-RLKKLVAEREDTISQLLQKCKEYQEQFQ-ELEAF---QQALQDMHNQNQGKELMIE 196 Query: 962 AQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINK----LNAL 1017 Q+Y N ++EL E VQ + Q ++ N++ K L A Sbjct: 197 TWKQKYIENDNKKQKEIDELKSKLAEFNPAEVQNLKDQFQRERQESQNQLKKQQSDLAAA 256 Query: 1018 LKQKDEEIIALN------QKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQL 1071 LKQ D+ I N Q++++AQ ++ V + + +T++ + E+ Q++ +L Sbjct: 257 LKQLDQWKIKYNNLDLQHQQLSSAQKESIARVETLTQEQNKLSTQIHQLNEDKQKLQIEL 316 Query: 1072 LDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMII-----SSTIEPMSDDAN 1126 +K + Q L+ E D K L + + + +++ I TI ++ Sbjct: 317 EQTKGQLKLHQGLIGELDRIKKLLSDKSAELQQMLQQSQQKDIDLNNAELTISELNQKIK 376 Query: 1127 NVDXXXXXXXXXXXXL--KVQEEEEFIQERSVLQEQSAK---LNTELQECYTKI----IQ 1177 ++ + +E E+ QE S L + K L E Q+ +K+ + Sbjct: 377 SLSLLQQENQRLQHEIDESHRENEKLAQENSQLLKDIDKFKLLEQEKQQLESKVSMLASE 436 Query: 1178 LETLNTELTGHD---VVNQEQINQLKSKL---EQLNTENDNLLSTVAELRSSISSAVDQR 1231 +E L +L + + QE + L+ +L EQL +N LL + E + I ++Q+ Sbjct: 437 IERLKVQLKQKNEKILEQQEDLKNLQEQLGEIEQLENQNQQLLKEL-EQKDKIIEELEQK 495 Query: 1232 GFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKY----EQLLDSVQSSTQEETNKIV 1287 E+ L +Q LA E+++ LSA + +Q + ++++ ++ ++ + Sbjct: 496 LQELNVL-EQKLADANNKIYDLENKV-AMLSAESQRLRYLNDQKTEQLKNAEEQLSDLNI 553 Query: 1288 TMEQVTSLQNKLQDKEEHLRNLQ---EKYADVINQ----IEILRSEIEDEKVA-FXXXXX 1339 E+++ LQNK +++ +N Q EK NQ I L+ ++E++K Sbjct: 554 LKEKLSQLQNKYDAQQQVNQNYQDELEKLRGQSNQANTNIAELKRQLEEQKAQDIIHKQS 613 Query: 1340 XXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAE 1399 L + QSYK++ E ++ N + L+ + Sbjct: 614 NSESVIAELQQQLSSLQQSYKKVSESNLANEEDPTLDLQNRLTLLKQENQRLNQTIQQKN 673 Query: 1400 AKVLELTHQ--------LELKDSEI-YQKTHEYTITLTQRNDEFENVRQQLVEYEKRIED 1450 +VL Q LEL ++ ++ HE L ++ RQ+L + ++ E Sbjct: 674 QEVLNHQQQNQNLQQELLELDSLKVQIKELHESNTVLQEQLQNEAKGRQELEQRIQQTES 733 Query: 1451 LTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELN- 1509 Y+ +S+ A+ L H Y+ + E+ + K I+EL ++ E +L ++ L Sbjct: 734 EKYDLQSKCAM--LSTHIEGMKYKLDKMENVDDLKKRIQELEGQLAEMQALELEIESLKD 791 Query: 1510 --KALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQG 1567 LE+E+ + +L+ Q + + + E ++N + SS+I++ + + KQ Sbjct: 792 RIAELEKELKLWKQKHESLD-QSYQQLQMTKE--QMENKLAMLSSEIER-LKVLNKKKQD 847 Query: 1568 RDEQLDNTMNK 1578 +Q + + K Sbjct: 848 EIDQQNQELIK 858 Score = 92.7 bits (220), Expect = 8e-17 Identities = 130/644 (20%), Positives = 292/644 (45%), Gaps = 51/644 (7%) Query: 234 DEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXX 293 DE R + + ++ ++ + KLLE + ++ + S LA E+E+ Sbjct: 393 DESHRENEKLAQENSQLLKDIDKFKLLEQEKQQLESKVSMLASEIERLKVQLKQKNEKIL 452 Query: 294 XLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTN----------- 342 ++ ++ E+ EIE+ + + EL +K +++E L ++++ N Sbjct: 453 E-QQEDLKNLQEQLGEIEQLENQNQQLLKELEQKDKIIEELEQKLQELNVLEQKLADANN 511 Query: 343 --KELENKLATMGTESKAVS-SPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTD 399 +LENK+A + ES+ + +K L + + + + +K SQL ++ D Sbjct: 512 KIYDLENKVAMLSAESQRLRYLNDQKTEQLKNAEEQLSDLNILKEKLSQLQNK---YDAQ 568 Query: 400 KKINKN---EIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLE- 455 +++N+N E+ KL N ++ + + + E+ +++IA+LQ + Sbjct: 569 QQVNQNYQDELEKLRGQSNQANTNIAELKRQLEEQ--KAQDIIHKQSNSESVIAELQQQL 626 Query: 456 --HQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQIT 513 QQ + S ++ + ++ LKQE N + ++ +++ + ++Q Sbjct: 627 SSLQQSYKKVSESNLANEEDPTLDLQNRLTLLKQE-NQRLNQ-TIQQKNQEVLNHQQQNQ 684 Query: 514 QLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTE-ELHHLSQKVA 572 L E+ + +++K H+ +Q+ + N +K ++ ++ TE E + L K A Sbjct: 685 NLQQELLELDSLKVQIKELHESN-TVLQEQLQNEAKGRQELEQRIQQTESEKYDLQSKCA 743 Query: 573 ELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEME-NLAETRLKAISL--LESQKFDLVQE 629 L ++ L D ++ D+ K++ E+E LAE + + + L+ + +L +E Sbjct: 744 MLSTHIEGMKYKL---DKMENVD-DLKKRIQELEGQLAEMQALELEIESLKDRIAELEKE 799 Query: 630 LHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDK 689 L + +QK++ ++ QLQ + E K L +I+ L K+ I+ + Sbjct: 800 LKLWKQKHESLDQ---SYQQLQMTKEQMENKLAMLSSEIERLKVLNKKKQDEIDQQNQEL 856 Query: 690 EQLYGTIKDLENDKEDI------MNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEE 743 +L + DL N EDI + L+N +Q+ +D D +K++ +I+ L ++ E Sbjct: 857 IKLDQEMNDLHNQLEDINELKTQLGSLENQLQQQID--DNQDKLN--EITHLKQQV-AEI 911 Query: 744 QSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLG 803 + + Q + +I++ + ++ + + ++K ++ +LE IA +ED +Y E K L Sbjct: 912 EGLLVNQEDLQNQIKKLETESQSKDEIIDQFKQKLTQLESKIAELEDIKYKYEDKMALLS 971 Query: 804 SYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHE 847 S ++ + + + +EL ++ L +++++E+E + Sbjct: 972 SEVKRYEFKAKKLEDKSNELTTQVDHLTADLNEADQKVIELEKD 1015 Score = 82.2 bits (194), Expect = 1e-13 Identities = 125/596 (20%), Positives = 270/596 (45%), Gaps = 49/596 (8%) Query: 213 DTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHS 272 + ++ + +QE +E + +++ Q+LLK++E KD I LE+ + L +++ ++ Sbjct: 453 EQQEDLKNLQEQLGEIE-QLENQNQQLLKELEQKDKIIEELEQKLQELNVLEQKLADANN 511 Query: 273 KLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLE 332 K+ +LE L Q E + ++ + L+ +++L K + + Sbjct: 512 KI-YDLENKVAMLSAESQRLRYLNDQKTEQLKNAEEQLSDLNILK-EKLSQLQNKYDAQQ 569 Query: 333 HLNCQIRQTNKELENKLATMGTESKAVSS--PSKKGSPLISRKSGRNTASKMKSPWSQLS 390 +N + ++L + T + +K +I ++S N+ S + QLS Sbjct: 570 QVNQNYQDELEKLRGQSNQANTNIAELKRQLEEQKAQDIIHKQS--NSESVIAELQQQLS 627 Query: 391 SETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIA 450 S Q + KK++++ +A E L L + +++ ++ L Sbjct: 628 S---LQQSYKKVSESNLANEEDPTLDLQNRL-----TLLKQENQRLNQTIQQKNQEVLNH 679 Query: 451 QLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEE 510 Q Q ++ Q L+ + + + E+ + L+++L +E K ++L ++++ E Sbjct: 680 QQQNQNLQQ----ELLELDSLKVQIKELHESNTVLQEQLQNEAK--GRQELEQRIQQTES 733 Query: 511 QITQLNDEIDAANKNMIKVKSNHKL-KLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQ 569 + L + + ++ +K +KL K++ + ++ E+ L E+ L Sbjct: 734 EKYDLQSKCAMLSTHIEGMK--YKLDKMENVDDLKKRIQELEGQLAEMQALELEIESLKD 791 Query: 570 KVAELEEE-KGNLQLH-LVD--YDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFD 625 ++AELE+E K Q H +D Y +M + + K+ + + E RLK ++ + + D Sbjct: 792 RIAELEKELKLWKQKHESLDQSYQQLQMTKEQMENKLAMLSSEIE-RLKVLNKKKQDEID 850 Query: 626 LV-QELHILQQKYDEVEDKLADISQLQSDQVCSEIK-SVHLEEQIDALS--ASKKELALV 681 QEL L Q+ +++ ++L DI++L++ E + +++ D L+ K+ Sbjct: 851 QQNQELIKLDQEMNDLHNQLEDINELKTQLGSLENQLQQQIDDNQDKLNEITHLKQQVAE 910 Query: 682 IENLKLDKEQLYGTIKDLEND---KEDI-------MNKLQNYIQENMDL----TDKLEKM 727 IE L +++E L IK LE + K++I + +L++ I E D+ DK+ + Sbjct: 911 IEGLLVNQEDLQNQIKKLETESQSKDEIIDQFKQKLTQLESKIAELEDIKYKYEDKMALL 970 Query: 728 SAE-KISELLAKINHEEQSKIQTQFG-IDAKIQERDLYIENIESELSKYKSRICRL 781 S+E K E AK ++ +++ TQ + A + E D + +E +L ++K +L Sbjct: 971 SSEVKRYEFKAKKLEDKSNELTTQVDHLTADLNEADQKVIELEKDLGQWKFEYSKL 1026 Score = 41.1 bits (92), Expect = 0.25 Identities = 88/465 (18%), Positives = 191/465 (41%), Gaps = 43/465 (9%) Query: 155 DNALSVLQVKMKIMETTILDLQEK--INEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXE 212 ++ ++ LQ ++ ++ + + E NE+D ++ +N+ T E Sbjct: 616 ESVIAELQQQLSSLQQSYKKVSESNLANEEDPTLDLQNRLTLLKQENQRLNQTIQQKNQE 675 Query: 213 --DTKQQMTKMQENFIAMEA------EWKDEKQRLLKDIESKDVRISSLEEANKLLEAAR 264 + +QQ +Q+ + +++ E + L + ++++ LE+ + E+ + Sbjct: 676 VLNHQQQNQNLQQELLELDSLKVQIKELHESNTVLQEQLQNEAKGRQELEQRIQQTESEK 735 Query: 265 FEISLEHSKLAQELEQXXXXXXXXXXXXXXLAK-QSIEPSCEEKTEIE-EKGSLEIANMT 322 +++ + + L+ +E + Q +E E +E E SL+ + Sbjct: 736 YDLQSKCAMLSTHIEGMKYKLDKMENVDDLKKRIQELEGQLAEMQALELEIESLK-DRIA 794 Query: 323 ELTKKIEL-------LEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSG 375 EL K+++L L+ Q++ T +++ENKLA + +E + + +KK I +++ Sbjct: 795 ELEKELKLWKQKHESLDQSYQQLQMTKEQMENKLAMLSSEIERLKVLNKKKQDEIDQQN- 853 Query: 376 RNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXX 435 K+ + L NQ D K ++ LE +Q D DK I+ Sbjct: 854 -QELIKLDQEMNDLH----NQLEDINELKTQLGSLENQLQQQIDDNQDKLNEITHLKQQV 908 Query: 436 XXXXXXXXGKDTL---IAQLQLEHQQHME-----GPSLIHVGTNTEDVNEIAKVQEQLKQ 487 ++ L I +L+ E Q E L + + ++ +I E Sbjct: 909 AEIEGLLVNQEDLQNQIKKLETESQSKDEIIDQFKQKLTQLESKIAELEDIKYKYEDKMA 968 Query: 488 ELNDEIK--DVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSN------HKLKLKQ 539 L+ E+K + K L +K Q+ L +++ A++ +I+++ + KL Sbjct: 969 LLSSEVKRYEFKAKKLEDKSNELTTQVDHLTADLNEADQKVIELEKDLGQWKFEYSKLNS 1028 Query: 540 MQKTIDNFS-KVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQL 583 +Q ID +S + S EI L ++ L++++ ++ K L L Sbjct: 1029 LQYKIDEYSFLLVVSFAEIEALRSQVTTLNEQLDGHQKTKVALAL 1073 >UniRef50_A0DI28 Cluster: Chromosome undetermined scaffold_51, whole genome shotgun sequence; n=1; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_51, whole genome shotgun sequence - Paramecium tetraurelia Length = 1335 Score = 136 bits (330), Expect = 4e-30 Identities = 184/919 (20%), Positives = 441/919 (47%), Gaps = 79/919 (8%) Query: 454 LEHQQHMEGPSLIHVGTNTEDVN----EIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAE 509 + + + G +I + D+N E A+ + L Q+LN +I++ ++ IE LK Sbjct: 64 INNSDDVSGAKIIQLEVEIHDLNQQLQESAQKIKALTQQLNAKIEENEME--IEILKDDH 121 Query: 510 EQ-ITQLNDEIDAANKNMIKVKSNHK-LKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHL 567 ++ ++ +I+A K + +++ K + KQ Q+ ++++D + + ++ + + Sbjct: 122 QKSLSDQQIQIEALQKTINELQQLQKNTETKQSQEIAP--TQLNDQEELLQKIQNLTNQI 179 Query: 568 SQKVAELE-EEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAE--TRLKAISLL---ES 621 Q +LE ++K QL L + G M E + E +NL E +L+ + L E+ Sbjct: 180 EQYAKQLEIKDKQIEQLQLNEGKQGSMEEVGK-RSQEEDQNLEEKIAQLEEVLLQYQEEN 238 Query: 622 QKFDLVQEL-----HILQQKYDEVEDKLADISQLQSD-QVCSEIKSVHLE--EQIDALSA 673 +F +E L+Q+ + +E ++ +I Q + D V +++ + LE E ++ ++ Sbjct: 239 SQFAAKEEASQKEKQQLKQQLESLEKQIKEIQQQEQDASVAQQLEDLKLEYEELVEEYTS 298 Query: 674 SKKELALV-IENLKL-DKEQLYGTIKD-LENDKEDIMNKLQNY---IQENMDLTDKLEKM 727 + ++L +E +L DK Q Y ++K+ L++ LQ++ ++EN +L + K Sbjct: 299 TNEKLQQSELECQQLTDKCQEYLSVKEQLQDQITQFETTLQHHNEVLEENNELKQLMNKA 358 Query: 728 SAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAV 787 S E+I+ L + N+E Q+ + Q + + + L+I E + Y++ + + + Sbjct: 359 S-EQINNLQS--NNEYQT-LYLQLRDEYEEFKEQLHITIKEKDQQLYQA--AQFCQELEA 412 Query: 788 MEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVE---KQLLEI 844 +++ + LE L + LQ + + +Y + +EL N+L L + ++ V ++L ++ Sbjct: 413 FKEQAHMLEENNTLLSNQLQTQLENNEKYQQRIEELENQLNTLQNQNQDVNDLMQKLDQL 472 Query: 845 EHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLE 904 + +N+ L+ +N E +N +I + ++Q +K ++ SE+T +L++ Sbjct: 473 KQDNENLKTQNYEYDEMIKNYEIQMDALKQIECDSPKKISKLQQENSETTAEYIKLKE-- 530 Query: 905 SNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQL 964 N +R H L+ Q++ +++ +E + +++ I + K + I+Y +L++ Sbjct: 531 -NTQREIH----LLKQERTNLQNEIVEIKSLLDTYINSGETFESKTQYIIDYWNKLQSIQ 585 Query: 965 QEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQK--- 1021 E N +E + ++ELN+ N+ +Q Q S D+ Q +N+ ++N+ K + Sbjct: 586 DEQNNLVEKFQLEIQELNE-NI----GQIQSLQNLSTDH--QQLNQELQINSSEKNELAA 638 Query: 1022 DEEI-IALNQKINNAQVS----YMSMVSDYESKLAQFTTKLENM------EEEMQRVSKQ 1070 DE + ++L + + N + + + + +++ + +T+ E++ ++++Q+ +Q Sbjct: 639 DENLNLSLEKLVTNEETNQNNFHFEVKKVQQTEYVEISTQTEDVIEQNQQQDQVQQQEQQ 698 Query: 1071 LLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDX 1130 +Q ++ Q ++Q Q ++ ++ + +E + +T+ +I S+ P + D D Sbjct: 699 QEQQQQQQQQQQQQQQQQQQQQQQQQQEQKQYESQLIQTDDVIFSA---PQNSDKETNDQ 755 Query: 1131 XXXXXXXXXXXLKV--QEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGH 1188 ++ Q E+ E++ ++ S +LN E + I +L N +L G Sbjct: 756 LCQTDEQKEDLQEIQGQNSEQQNNEQNGIELNSQQLNGEQDHDQSIITKLMQPNEDLDGQ 815 Query: 1189 DVVNQE--QINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQR 1246 Q+ Q +QLK K+E ++ +L V L+ + ++++ +I + Q Sbjct: 816 GSQFQDLNQTDQLKKKVEDMDNLRKSLEKEVYNLKDK-NKKLEEK-LQIIQKPGTPRKQS 873 Query: 1247 EADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTME--QVTSLQNKLQDKEE 1304 +A ++ + + + + + ++L + +QS + N+ + + ++ LQ++++ +E Sbjct: 874 DAKEERKKQQDNELIQRLQKQIKELQEEIQSFNVHQLNEQIEQQSNEIEQLQSEIEQYKE 933 Query: 1305 HLRNLQEKYADVINQIEIL 1323 L +++ NQ++ + Sbjct: 934 QLIKQKQQTIKFKNQLDTI 952 Score = 107 bits (256), Expect = 3e-21 Identities = 193/971 (19%), Positives = 409/971 (42%), Gaps = 86/971 (8%) Query: 650 LQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNK 709 LQ ++ EI + EQ+ L KE I+ KLD IK+L+ ++ + K Sbjct: 3 LQVQKLQQEITDLKEYEQM--LEDQIKEHEETIDKQKLDLNTKETEIKNLKKQLQEAIKK 60 Query: 710 LQNYIQENMDLTD-KLEKMSAEKISELLAKINHEEQS-KIQTQFGIDAKIQERDLYIENI 767 + I + D++ K+ ++ E I +L ++ Q K TQ ++AKI+E ++ IE + Sbjct: 61 A-DVINNSDDVSGAKIIQLEVE-IHDLNQQLQESAQKIKALTQ-QLNAKIEENEMEIEIL 117 Query: 768 ESE----LSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDEL 823 + + LS + +I L+++I ++ + + E K Q + Q + IQ L Sbjct: 118 KDDHQKSLSDQQIQIEALQKTINELQQLQKNTETKQSQEIAPTQLNDQEELLQKIQN--L 175 Query: 824 VNRLAVLMDHDRVVEKQLLEIE-HENKE--LQKKNQILLEENQNLQISLSDMQ----QHY 876 N++ + +KQ+ +++ +E K+ +++ + EE+QNL+ ++ ++ Q+ Sbjct: 176 TNQIEQYAKQLEIKDKQIEQLQLNEGKQGSMEEVGKRSQEEDQNLEEKIAQLEEVLLQYQ 235 Query: 877 NALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQI 936 + A + + ++ E + + QL LE +K I + Q V + ++EDL++E+ Sbjct: 236 EENSQFAAKEEASQKEKQQLKQQLESLEKQIKEIQQQEQDASVAQ--QLEDLKLEY---- 289 Query: 937 ESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQ 996 E + + NEK +++ QL + QEY ++V+E +L D+ Q + Sbjct: 290 EELVEEYTSTNEKLQQSELECQQLTDKCQEY--------LSVKE------QLQDQITQFE 335 Query: 997 QTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTK 1056 T + + + E N+L L+ + E+I L Q N Q Y+ + +YE Q Sbjct: 336 TTLQ--HHNEVLEENNELKQLMNKASEQINNL-QSNNEYQTLYLQLRDEYEEFKEQLHIT 392 Query: 1057 LENMEEEMQRVSKQLLDSKQHNEELQILVREQ---DDQIKELKETKLTFEMNIPKTEGMI 1113 ++ ++++ + ++ + + E+ +L +Q++ E ++ I + E + Sbjct: 393 IKEKDQQLYQAAQFCQELEAFKEQAHMLEENNTLLSNQLQTQLENNEKYQQRIEELENQL 452 Query: 1114 ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQ--EEEEFIQERSVLQEQSAKLNTELQEC 1171 +T++ + D N++ LK Q E +E I+ + + ++ + + Sbjct: 453 --NTLQNQNQDVNDLMQKLDQLKQDNENLKTQNYEYDEMIKNYEIQMDALKQIECDSPK- 509 Query: 1172 YTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQR 1231 KI +L+ N+E T + +E + ++ L E NL + + E++S + + ++ Sbjct: 510 --KISKLQQENSETTAEYIKLKENTQR---EIHLLKQERTNLQNEIVEIKSLLDTYINSG 564 Query: 1232 GFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQ 1291 E E Q++ Q + E + F+ + ++L +++ Q N +Q Sbjct: 565 --ETFESKTQYIIDYWNKLQSIQDEQNNLVEKFQLEIQELNENI-GQIQSLQNLSTDHQQ 621 Query: 1292 VTS-LQNKLQDKEEHL--RNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXX 1348 + LQ +K E NL ++ E ++ E Sbjct: 622 LNQELQINSSEKNELAADENLNLSLEKLVTNEETNQNNFHFE---VKKVQQTEYVEISTQ 678 Query: 1349 XXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQ 1408 D+ +NQ Q+Q+Q +E Q ++ + E K E Sbjct: 679 TEDVIEQNQQQDQVQQQEQ---QQEQQQQQQQQQQQQQQQQQQQQQQQQQEQKQYE---- 731 Query: 1409 LELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHE 1468 S++ Q T + + Q +D+ N QL + +++ EDL E + + + + + Sbjct: 732 -----SQLIQ-TDDVIFSAPQNSDKETN--DQLCQTDEQKEDLQ-EIQGQNSEQQ-NNEQ 781 Query: 1469 NANHYETMQKESEIERVKLIEELNVKITESVS-LNKQVAELNKALEEEVAKTNEMQTALE 1527 N + Q E + + I ++ E + Q +LN+ ++ K +M + Sbjct: 782 NGIELNSQQLNGEQDHDQSIITKLMQPNEDLDGQGSQFQDLNQT-DQLKKKVEDMDNLRK 840 Query: 1528 NQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRA 1587 + E E+ L D+ L+ ++ SD K+ R +Q DN + + L + Sbjct: 841 SLEKEVYNLKDKNKKLEEKLQIIQKPGTPRKQ--SDAKEERKKQQDNELIQRLQKQIKEL 898 Query: 1588 ELDLAMYMLHQ 1598 + ++ + +HQ Sbjct: 899 QEEIQSFNVHQ 909 Score = 100 bits (240), Expect = 3e-19 Identities = 214/1059 (20%), Positives = 447/1059 (42%), Gaps = 88/1059 (8%) Query: 498 VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSN--- 554 + DL E + E+QI + + ID ++ ++ K KQ+Q+ I +++S+ Sbjct: 12 ITDLKEYEQMLEDQIKEHEETIDKQKLDLNTKETEIKNLKKQLQEAIKKADVINNSDDVS 71 Query: 555 -KEIVRLTEELHHLSQKVAELEEE-KGNLQLHLVDYDSGRM----IESDVYKKMIEMENL 608 +I++L E+H L+Q++ E ++ K Q + M ++ D K + + + Sbjct: 72 GAKIIQLEVEIHDLNQQLQESAQKIKALTQQLNAKIEENEMEIEILKDDHQKSLSDQQIQ 131 Query: 609 AETRLKAISLLE--SQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHL-E 665 E K I+ L+ + + Q I + ++ E+ L I L ++Q+ K + + + Sbjct: 132 IEALQKTINELQQLQKNTETKQSQEIAPTQLNDQEELLQKIQNL-TNQIEQYAKQLEIKD 190 Query: 666 EQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLE 725 +QI+ L ++ + + E K +E+ ++LE + L Y +EN K E Sbjct: 191 KQIEQLQLNEGKQGSMEEVGKRSQEE----DQNLEEKIAQLEEVLLQYQEENSQFAAKEE 246 Query: 726 KMSAEKISELLAKINH-EEQSKIQTQFGIDAKI--QERDLYIENIESELSKYKSRICRLE 782 EK +L ++ E+Q K Q DA + Q DL +E E + +Y S +L+ Sbjct: 247 ASQKEK-QQLKQQLESLEKQIKEIQQQEQDASVAQQLEDLKLE-YEELVEEYTSTNEKLQ 304 Query: 783 ESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLL 842 +S ++ D+ YL K++ + T E L + VL +++ + KQL+ Sbjct: 305 QS-------ELECQQLTDKCQEYLSVKEQLQDQITQFETTLQHHNEVLEENNEL--KQLM 355 Query: 843 EIEHEN-KELQKKNQILLEENQNLQISLSD-----MQQHYNALVEKANRTDLAE---SES 893 E LQ N E Q L + L D +Q + + EK + A E Sbjct: 356 NKASEQINNLQSNN-----EYQTLYLQLRDEYEEFKEQLHITIKEKDQQLYQAAQFCQEL 410 Query: 894 TKYQTQLRDLESNLKRITHEHQTLIVQKKK---EIEDLEIEFNTQIESAIRDKKVLNEKY 950 ++ Q LE N ++++ QT + +K IE+LE + NT +++ +D L +K Sbjct: 411 EAFKEQAHMLEENNTLLSNQLQTQLENNEKYQQRIEELENQLNT-LQNQNQDVNDLMQKL 469 Query: 951 EKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINE 1010 ++ + L+ Q EY I+N + ++ L ++ + K + K Q ++ + T +YI Sbjct: 470 DQLKQDNENLKTQNYEYDEMIKNYEIQMDALKQIECD-SPKKISKLQQENSETTAEYIK- 527 Query: 1011 INKLNALLKQKDEEIIALNQKINNAQ---VSYMSMVSDYESKLAQFTTKLENMEEEMQRV 1067 L + EI L Q+ N Q V S++ Y + F +K + + + ++ Sbjct: 528 ------LKENTQREIHLLKQERTNLQNEIVEIKSLLDTYINSGETFESKTQYIIDYWNKL 581 Query: 1068 SKQLLDSKQHN--EELQILVREQDDQIKELKETK-LTFEMNIPKTEGMIISSTIEPMSDD 1124 Q + +Q+N E+ Q+ ++E ++ I +++ + L+ + E I SS ++ D Sbjct: 582 --QSIQDEQNNLVEKFQLEIQELNENIGQIQSLQNLSTDHQQLNQELQINSSEKNELAAD 639 Query: 1125 AN-NVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNT-ELQECYTKIIQLETLN 1182 N N+ E + +Q+ ++ + + E + ++ Q E Sbjct: 640 ENLNLSLEKLVTNEETNQNNFHFEVKKVQQTEYVEISTQTEDVIEQNQQQDQVQQQEQQQ 699 Query: 1183 TELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQH 1242 + Q+Q Q + + +Q E S + + I SA E + Q Sbjct: 700 EQQQQQQQQQQQQQQQQQQQQQQQQQEQKQYESQLIQTDDVIFSAPQNSDKETNDQLCQT 759 Query: 1243 LAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDK 1302 Q+E D Q+ + + Q + ++ E L+S Q + +++ ++ S+ KL Sbjct: 760 DEQKE-DLQEIQGQNSEQQNNEQNGIE--LNSQQLNGEQDHDQ--------SIITKLMQP 808 Query: 1303 EEHLRNLQEKYADVINQIEILRSEIED-EKVAFXXXXXXXXXXXXXXXXDLRTE-NQSYK 1360 E L ++ D +NQ + L+ ++ED + + + + + Q Sbjct: 809 NEDLDGQGSQFQD-LNQTDQLKKKVEDMDNLRKSLEKEVYNLKDKNKKLEEKLQIIQKPG 867 Query: 1361 QMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKT 1420 ++QS + EE + + + + V +L Q+E + +EI Q Sbjct: 868 TPRKQS--DAKEERKKQQDNELIQRLQKQIKELQEEIQSFNVHQLNEQIEQQSNEIEQLQ 925 Query: 1421 HEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKES 1480 E + Q ++ +QQ ++++ +++ + L +L+ + + + + +Q+E Sbjct: 926 SE----IEQYKEQLIKQKQQTIKFKNQLDTIYNLGPQALTMLQSEPKKEFSSTQLIQQEK 981 Query: 1481 -EIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAK 1518 +I I+ + + LN++ +L ++++ ++ K Sbjct: 982 YQISSFLYIKSQKSYQCQFIELNRKQIKLFQSIKGKIEK 1020 Score = 91.9 bits (218), Expect = 1e-16 Identities = 145/724 (20%), Positives = 305/724 (42%), Gaps = 57/724 (7%) Query: 887 DLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNT---QIESAIRDK 943 DL + + T L++ E L+ EH+ I ++K ++ E E Q++ AI+ Sbjct: 2 DLQVQKLQQEITDLKEYEQMLEDQIKEHEETIDKQKLDLNTKETEIKNLKKQLQEAIKKA 61 Query: 944 KVLNEKYEKNIEYVTQLEA-------QLQEYKNNI----ENLNMNVEELNKMNLELIDKH 992 V+N + + + QLE QLQE I + LN +EE N+M +E++ Sbjct: 62 DVINNSDDVSGAKIIQLEVEIHDLNQQLQESAQKIKALTQQLNAKIEE-NEMEIEILKDD 120 Query: 993 VQK----QQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYES 1048 QK QQ Q + ++ INE+ +L + K + IA Q N Q + + + + Sbjct: 121 HQKSLSDQQIQI-EALQKTINELQQLQKNTETKQSQEIAPTQL--NDQEELLQKIQNLTN 177 Query: 1049 KLAQFTTKLENMEEEMQRVSKQLLDSKQHN-EELQILVREQDDQIKE----LKETKLTFE 1103 ++ Q+ +LE +++++++ QL + KQ + EE+ +E+D ++E L+E L ++ Sbjct: 178 QIEQYAKQLEIKDKQIEQL--QLNEGKQGSMEEVGKRSQEEDQNLEEKIAQLEEVLLQYQ 235 Query: 1104 MNIPKTEGMIISSTIEP--MSDDANNVDXXXXXXXXXXXXLKV-QEEEEFIQERSVLQEQ 1160 + +S E + +++ V Q+ E+ E L E+ Sbjct: 236 EENSQFAAKEEASQKEKQQLKQQLESLEKQIKEIQQQEQDASVAQQLEDLKLEYEELVEE 295 Query: 1161 SAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAEL 1220 N +LQ+ + QL E Q+QI Q ++ L+ N +L EL Sbjct: 296 YTSTNEKLQQSELECQQLTDKCQEYLSVKEQLQDQITQFETTLQHHN----EVLEENNEL 351 Query: 1221 RSSISSAVDQ-RGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSST 1279 + ++ A +Q + ++ Q ++++ + +L + + + + Q Q Sbjct: 352 KQLMNKASEQINNLQSNNEYQTLYLQLRDEYEEFKEQLHITIKEKDQQLYQAAQFCQELE 411 Query: 1280 QEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXX 1339 + + E T L N+LQ + E+ Q++ ++ NQ+ L+++ +D Sbjct: 412 AFKEQAHMLEENNTLLSNQLQTQLENNEKYQQRIEELENQLNTLQNQNQD-----VNDLM 466 Query: 1340 XXXXXXXXXXXDLRTENQSYKQMQEQSILNINE----ENAQLKKSSXXXXXXXXXXXXRV 1395 +L+T+N Y +M + + ++ E KK S + Sbjct: 467 QKLDQLKQDNENLKTQNYEYDEMIKNYEIQMDALKQIECDSPKKISKLQQENSETTAEYI 526 Query: 1396 NDAEAKVLELTHQLELKDSEIYQKTHEYTI---TLTQRNDEFENVRQQLVEYEKRIEDLT 1452 E E+ H L+ + + + + E T + FE+ Q +++Y +++ + Sbjct: 527 KLKENTQREI-HLLKQERTNLQNEIVEIKSLLDTYINSGETFESKTQYIIDYWNKLQSIQ 585 Query: 1453 YEKESELAILRL---KMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELN 1509 E+ + + +L +++EN +++Q S + +L +EL + +E L LN Sbjct: 586 DEQNNLVEKFQLEIQELNENIGQIQSLQNLS-TDHQQLNQELQINSSEKNELAAD-ENLN 643 Query: 1510 KALEEEVA--KTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQG 1567 +LE+ V +TN+ E ++++ + T ++++ + + Q +Q Sbjct: 644 LSLEKLVTNEETNQNNFHFEVKKVQQTEYVEISTQTEDVIEQNQQQDQVQQQEQQQEQQQ 703 Query: 1568 RDEQ 1571 + +Q Sbjct: 704 QQQQ 707 Score = 55.6 bits (128), Expect = 1e-05 Identities = 135/680 (19%), Positives = 278/680 (40%), Gaps = 73/680 (10%) Query: 220 KMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELE 279 ++Q+ E + + L ++ E K + + E+ N L + E + +L E E Sbjct: 326 QLQDQITQFETTLQHHNEVLEENNELKQLMNKASEQINNL--QSNNEYQTLYLQLRDEYE 383 Query: 280 QXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIR 339 + Q+ + C+E +E+ + N T L+ +++ N + + Sbjct: 384 EFKEQLHITIKEKDQQLYQAAQ-FCQELEAFKEQAHMLEENNTLLSNQLQTQLENNEKYQ 442 Query: 340 QTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTD 399 Q +ELEN+L T+ +++ V+ +K L ++ N +T N + D Sbjct: 443 QRIEELENQLNTLQNQNQDVNDLMQKLDQL--KQDNENL-------------KTQNYEYD 487 Query: 400 KKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQH 459 + I EI + +L + D IS+ +T ++L+ Sbjct: 488 EMIKNYEIQ-----MDALKQIECDSPKKISKLQQE---------NSETTAEYIKLKENTQ 533 Query: 460 MEGPSLIHVGTNTEDVNEIAKVQEQLKQELND----EIKDVNVKDLIEKLKSAEEQITQL 515 E L TN + NEI +++ L +N E K + D KL+S +++ L Sbjct: 534 REIHLLKQERTNLQ--NEIVEIKSLLDTYINSGETFESKTQYIIDYWNKLQSIQDEQNNL 591 Query: 516 ND----EIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKV 571 + EI N+N+ +++S L Q ++ +++ S K + E L+ +K+ Sbjct: 592 VEKFQLEIQELNENIGQIQSLQNLSTDHQQ--LNQELQINSSEKNELAADENLNLSLEKL 649 Query: 572 AELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELH 631 EE N H ++ ++ +++ + + E++ E + ++ Q+ Q+ Sbjct: 650 VTNEETNQN-NFH---FEVKKVQQTEYVEISTQTEDVIEQNQQQ-DQVQQQEQQQEQQQQ 704 Query: 632 ILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQI-DALSASKKELALVIENLKLDKE 690 QQ+ + + + Q Q +Q E + + ++ I A S KE + KE Sbjct: 705 QQQQQQQQQQQQQQQQQQQQQEQKQYESQLIQTDDVIFSAPQNSDKETNDQLCQTDEQKE 764 Query: 691 QLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQ 750 L ++++ + N QN I+ N + + I++L+ + Q Q Sbjct: 765 DL----QEIQGQNSEQQNNEQNGIELNSQQLNGEQDHDQSIITKLMQPNEDLDGQGSQFQ 820 Query: 751 F-----GIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMED----RRYS---LERK 798 + K+++ D +++E E+ K + +LEE + +++ R+ S ERK Sbjct: 821 DLNQTDQLKKKVEDMDNLRKSLEKEVYNLKDKNKKLEEKLQIIQKPGTPRKQSDAKEERK 880 Query: 799 ADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKEL-QKKNQI 857 Q +Q QK E +QE+ + V ++++ E+Q EIE E+ Q K Q+ Sbjct: 881 KQQDNELIQRLQKQIKE--LQEE--IQSFNVHQLNEQI-EQQSNEIEQLQSEIEQYKEQL 935 Query: 858 LLEENQNLQISLSDMQQHYN 877 + ++ Q ++ + + YN Sbjct: 936 IKQKQQTIKFK-NQLDTIYN 954 Score = 47.6 bits (108), Expect = 0.003 Identities = 117/667 (17%), Positives = 275/667 (41%), Gaps = 53/667 (7%) Query: 216 QQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLA 275 Q + Q ++ + E+++ K++L I+ KD ++ + + LEA + E + + Sbjct: 366 QSNNEYQTLYLQLRDEYEEFKEQLHITIKEKDQQLYQAAQFCQELEAFK-----EQAHML 420 Query: 276 QELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLN 335 +E +Q IE + ++ + ++ +L +K++ L+ N Sbjct: 421 EENNTLLSNQLQTQLENNEKYQQRIEELENQLNTLQNQNQ----DVNDLMQKLDQLKQDN 476 Query: 336 CQIRQTNKELENKLATMGTES---KAVSSPSKKGSPLISRKSGRNTASKMK-SPWSQLSS 391 ++ N E + + + K + S K + +++ TA +K +Q Sbjct: 477 ENLKTQNYEYDEMIKNYEIQMDALKQIECDSPKKISKLQQENSETTAEYIKLKENTQREI 536 Query: 392 ETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQ 451 L Q+ +NEI +++ ++ + E ++ L+ + Sbjct: 537 HLLKQERTNL--QNEIVEIKSLLDTYINSGETFESKTQYIIDYWNKLQSIQDEQNNLVEK 594 Query: 452 LQLEHQQHMEG----PSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKS 507 QLE Q+ E SL ++ T+ + +N+ ++ K EL D N+ +EKL + Sbjct: 595 FQLEIQELNENIGQIQSLQNLSTDHQQLNQELQINSSEKNEL---AADENLNLSLEKLVT 651 Query: 508 AEE-QITQLNDEIDAANKN-MIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELH 565 EE + E+ + +++ + + ++Q Q+ +V ++ + ++ Sbjct: 652 NEETNQNNFHFEVKKVQQTEYVEISTQTEDVIEQNQQQ----DQVQQQEQQQEQQQQQQQ 707 Query: 566 HLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFD 625 Q+ + ++++ Q Y+S ++I++D + ET + + QK D Sbjct: 708 QQQQQQQQQQQQQQQQQQEQKQYES-QLIQTDDVIFSAPQNSDKETN-DQLCQTDEQKED 765 Query: 626 LVQELHILQQKYDEVEDKLADIS--QLQSDQVCSE---IKSVHLEEQIDALSASKKELAL 680 L QE+ + E +++ QL +Q + K + E +D + ++L Sbjct: 766 L-QEIQGQNSEQQNNEQNGIELNSQQLNGEQDHDQSIITKLMQPNEDLDGQGSQFQDLNQ 824 Query: 681 VIENLKLDKEQLYGTIKDLENDK---EDIMNKLQNYIQ---------ENMDLTDKLEKMS 728 + LK E + K LE + +D KL+ +Q + D ++ +K Sbjct: 825 T-DQLKKKVEDMDNLRKSLEKEVYNLKDKNKKLEEKLQIIQKPGTPRKQSDAKEERKKQQ 883 Query: 729 AEKISELLAKINHEEQSKIQT--QFGIDAKIQERDLYIENIESELSKYKSRICRLEESIA 786 ++ + L K E Q +IQ+ ++ +I+++ IE ++SE+ +YK ++ + ++ Sbjct: 884 DNELIQRLQKQIKELQEEIQSFNVHQLNEQIEQQSNEIEQLQSEIEQYKEQLIKQKQQTI 943 Query: 787 VMEDRRYSLERKADQLGSYLQ-EKQKAYSE-YTIQEDELVNRLAVLMDHDRVVEKQLLEI 844 +++ ++ Q + LQ E +K +S IQ+++ + + + + Q +E+ Sbjct: 944 KFKNQLDTIYNLGPQALTMLQSEPKKEFSSTQLIQQEKYQISSFLYIKSQKSYQCQFIEL 1003 Query: 845 EHENKEL 851 + +L Sbjct: 1004 NRKQIKL 1010 >UniRef50_A0CUZ8 Cluster: Chromosome undetermined scaffold_29, whole genome shotgun sequence; n=1; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_29, whole genome shotgun sequence - Paramecium tetraurelia Length = 1389 Score = 136 bits (330), Expect = 4e-30 Identities = 255/1291 (19%), Positives = 564/1291 (43%), Gaps = 122/1291 (9%) Query: 317 EIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGR 376 E+ + L K + ++ + +Q N++ K+ + + + + S I++ + Sbjct: 151 EVYRLRSLNDKSKYVQEESYHYQQENQQYLAKIRQLEMQIRDLMSKEDNYIMQINKAAQG 210 Query: 377 NTASKM--KSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISE--KD 432 N M K +QL + L ++ K +LE + Q +K L D+ I+ KD Sbjct: 211 NNNENMILKEQNAQLQQQLL------QLQKQYQKQLEDMSQERDKILSDQRNTINIQIKD 264 Query: 433 TXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNT--EDVNEIAKVQEQLKQ--- 487 ++ L+ ++QL QQ + I E+VN + +L+Q Sbjct: 265 QLLREQQKWQNEREALLQEIQLLKQQLSQNEQQILRKRQQIEEEVNRNQQYLIELEQGNT 324 Query: 488 ELNDEIKDV-NVKDLIEKLKSAEEQITQLNDE----IDAANKNMIKVKSNHKLKLKQM-Q 541 +L + +++ N L+EK K +Q T+ DE +D + M + + + L+Q Q Sbjct: 325 QLQNRCRELQNQISLMEKDKHRIDQYTRRIDEQQQQLDQLQRQMYDLTNKYNNLLQQYEQ 384 Query: 542 KTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKK 601 K N S N + +E H QK+ LE++ LQ L D R + + + Sbjct: 385 KKYQNEQLNSQLN-----MVQE--HDKQKIINLEKQIRELQDQLADTQRLRQQLNQMNEN 437 Query: 602 MIEMENLAETRLKAISLLESQKFDLVQELHILQQ-KYDEVEDKLADISQLQSDQVCSEIK 660 ++ +T K + + +L+Q L+ K +V++K D+ Q +S + E + Sbjct: 438 YTALQLSFKTSQKQLQDFDELNQELIQLQRELEYYKQQDVKNK-QDLDQYKSQLLMIENR 496 Query: 661 -SVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNY-IQENM 718 + +++ L ++L + NL+ +QL + +ND + QNY + E+ Sbjct: 497 QNQQANSELEKLKYQNQQLNDELNNLRNTNQQLTFKFQQAQNDLQS-----QNYALNESN 551 Query: 719 DLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRI 778 L K++++ ++I +IN +++ + Q + + Q+ DL I +E E ++ RI Sbjct: 552 QLKAKIKEL-LDQIQYQQIEINKKDKLIQELQIKLQQQNQKIDLII-TMEKERKDFEYRI 609 Query: 779 CRLEESIA---VMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDR 835 +LE+ +A + + + L+ K + L + + EY + ++V L D + Sbjct: 610 IQLEKQLADSNLYKSQFIELQSKYENLRKDYELLRIKLEEYNNMQQKMVWLEKQLADAN- 668 Query: 836 VVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTK 895 + + Q LE+E++ L Q + + + Q+ ++M + A ++ + E+E K Sbjct: 669 IYKTQYLELENKYNNLDANYQFKISQLEK-QLQEANMYKMQYAELQNKYNFIIQENEIVK 727 Query: 896 YQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIE 955 +D E ++ + LI+ KK+ + I+FNT+ ++ + + K + Sbjct: 728 -----KDYEQLRYKLEEVNNQLIISKKQ----ITIQFNTEFDALKSEMQTWILKCKTYEN 778 Query: 956 YVTQLEAQLQEYKNNIENLNMNVE-ELNKMNLELIDKHVQKQQT----QSPDYTEQYINE 1010 + L + +++Y++N +N N+ V+ EL + ++ + ++QQ Q D IN+ Sbjct: 779 EINFLRSTIKDYQDN-DNENLLVKKELERWQIKCSELERERQQLKLNLQELDKLRYRIND 837 Query: 1011 INKLNALLKQK----DEEIIALNQKI---NNAQVSYMSMVSDYES---KLAQFTTKLENM 1060 + K N + K ++E A Q+I + Y + DY++ +L + + + Sbjct: 838 LEKDNQNYQFKIARLEKEADATRQQIIILEQQRTQYDLIKKDYDALQIRLQEQEREKSQL 897 Query: 1061 EEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEP 1120 EM + +QL +Q ++Q+L +E++ + +L+E+ E K + +I+++T Sbjct: 898 RNEMDILRQQL---QQFKSQVQMLEQERNQSLMKLEESDR--ERQGLKQQILILNNT--- 949 Query: 1121 MSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLET 1180 + N+ +E E F Q+ L ++ L +LQ + + + Sbjct: 950 -KVELENIR---------------REYENFKQKYEQLDRETISLRQQLQILNNQKGEFDR 993 Query: 1181 LNTELTGHDVVNQEQINQ---LKSKLEQLNTENDNLLSTVAE---LRSSISSAVDQRGFE 1234 + E + + +EQ + L+S+L+ + + ++L E +R + + + + Sbjct: 994 IKVEYSQLKINVEEQDREHLSLRSQLQLASNQKNDLEKFRQEYDIIRIKLEESEKDKN-Q 1052 Query: 1235 IAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKI-VTMEQVT 1293 + + ++ A + EH L +Q+S F+ Q L S Q +I + ++Q+ Sbjct: 1053 VKSQLQVYITNINAYKDQIEH-LNIQISQFQ----QDLSSFQQQEIMMKREIEMLIQQID 1107 Query: 1294 SLQNKLQDKEEHLRNLQEKYADVINQIEILRS-EIEDEKVAFXXXXXXXXXXXXXXXXDL 1352 + Q+K++ ++ Q KY +++ + E+L+S ++ + A Sbjct: 1108 IFKKDQQNKQQQIQEFQFKYQEILREYEVLQSKQVNIDVDALMYEIFELKKQLVQKEKQY 1167 Query: 1353 RTENQSYKQMQEQSILNIN-EENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLEL 1411 E Q Y + + QS NI ++++ + ++ + + L++ +L L Sbjct: 1168 EIERQEYLEQKFQSEKNIKLRVEQEIRQITERYNFEREELRKQIQVEKQQKLQIETELRL 1227 Query: 1412 KDSE---IYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHE 1468 K + I QK + I + + +++Q+V ++++E L E+ +RL++ + Sbjct: 1228 KYEQQILILQKQIKPVIDVDALMYDIFELKKQVVAKDQQLEQLKKEQYQ----MRLQIEQ 1283 Query: 1469 NANHYETMQKESEIERVKLIEELNVKITESVSLN-KQVAELNKALEEEVAKTNEMQTALE 1527 N + M+ ESE+ RVKL EL + I + + + ++ +++ + + + ++ + Sbjct: 1284 QFNQ-QRMKFESEL-RVKLERELRMSIESEIRFQIENDYKFDQNIQDYILQVEKWKSVCQ 1341 Query: 1528 NQEIEIVTLNDEITNLQNMVRASSSKIQKHV 1558 ++ EI D + LQ ++ ++ + + Sbjct: 1342 MRDEEI----DHMRGLQQALKEKLNQYTQEI 1368 Score = 109 bits (262), Expect = 6e-22 Identities = 256/1317 (19%), Positives = 548/1317 (41%), Gaps = 120/1317 (9%) Query: 168 METTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIA 227 M ++ + +E+I + QII+ N Q +Q++ Sbjct: 74 MNQSVKEYEEEIQRQKQIIDRLNLDLDKAKRDNEQLLQGFNDIKHRGLSQEQNLQQDNQR 133 Query: 228 MEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSK-LAQ--ELEQXXXX 284 M+ D L++++ + R+ SL + +K ++ + E+ + LA+ +LE Sbjct: 134 MK-HTIDGLNNDLRNLQQEVYRLRSLNDKSKYVQEESYHYQQENQQYLAKIRQLEMQIRD 192 Query: 285 XXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKE 344 ++ + + E ++E+ + + +L K+ + + L ++ +K Sbjct: 193 LMSKEDNYIMQINKAAQGNNNENMILKEQNAQLQQQLLQLQKQYQ--KQLEDMSQERDKI 250 Query: 345 LENKLATMGTESK-AVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLN--QDTDKK 401 L ++ T+ + K + +K R++ +K SQ + L Q +++ Sbjct: 251 LSDQRNTINIQIKDQLLREQQKWQN--EREALLQEIQLLKQQLSQNEQQILRKRQQIEEE 308 Query: 402 INKNE--IAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQL-QLEHQQ 458 +N+N+ + +LE L + + IS + D QL QL+ Q Sbjct: 309 VNRNQQYLIELEQGNTQLQNRCRELQNQISLMEKDKHRIDQYTRRIDEQQQQLDQLQRQM 368 Query: 459 HMEGPSLIHVGTNTEDVNEIAKVQ-EQLKQELN-----DEIKDVNVKDLIEKLKSAEEQI 512 + L + N E K Q EQL +LN D+ K +N++ I +L+ Sbjct: 369 Y----DLTNKYNNLLQQYEQKKYQNEQLNSQLNMVQEHDKQKIINLEKQIRELQDQLADT 424 Query: 513 TQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVA 572 +L +++ N+N + +L K QK + +F ++ N+E+++L EL + Q+ Sbjct: 425 QRLRQQLNQMNENYTAL----QLSFKTSQKQLQDFDEL---NQELIQLQRELEYYKQQDV 477 Query: 573 ELEE--EKGNLQLHLVDYDSGRMIESDVYKKMI-------EMENLAETRLKAISLLESQK 623 + ++ ++ QL +++ + S++ K E+ NL T + + + Sbjct: 478 KNKQDLDQYKSQLLMIENRQNQQANSELEKLKYQNQQLNDELNNLRNTNQQLTFKFQQAQ 537 Query: 624 FDLVQELHILQQKYDEVEDKLAD-ISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVI 682 DL + + L + ++++ K+ + + Q+Q Q+ K ++E L +++ L+I Sbjct: 538 NDLQSQNYALNES-NQLKAKIKELLDQIQYQQIEINKKDKLIQELQIKLQQQNQKIDLII 596 Query: 683 ENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHE 742 K K+ Y I+ LE D + L Y + ++L K E + K ELL +I E Sbjct: 597 TMEKERKDFEYRIIQ-LEKQLAD--SNL--YKSQFIELQSKYENL--RKDYELL-RIKLE 648 Query: 743 EQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQL 802 E + +Q++ +++E ++ + YK++ LE + D Y K QL Sbjct: 649 EYN----------NMQQKMVWLEKQLADANIYKTQYLELENKYNNL-DANYQF--KISQL 695 Query: 803 GSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEEN 862 LQE + Y +Q EL N+ ++ + +V+K ++ ++ +E+ NQ+++ + Sbjct: 696 EKQLQEA----NMYKMQYAELQNKYNFIIQENEIVKKDYEQLRYKLEEV--NNQLIISKK 749 Query: 863 QNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRI-THEHQTLIVQK 921 QI++ ++AL + L + Y+ ++ L S +K ++++ L+V Sbjct: 750 ---QITI-QFNTEFDALKSEMQTWIL---KCKTYENEINFLRSTIKDYQDNDNENLLV-- 800 Query: 922 KKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEEL 981 KKE+E +I+ +++E + K+ ++ +K + LE Q Y+ I L + Sbjct: 801 KKELERWQIKC-SELERERQQLKLNLQELDKLRYRINDLEKDNQNYQFKIARLEKEA-DA 858 Query: 982 NKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMS 1041 + + ++++ + DY I + + Q E+ L Q++ + S Sbjct: 859 TRQQIIILEQQRTQYDLIKKDYDALQI-RLQEQEREKSQLRNEMDILRQQLQ----QFKS 913 Query: 1042 MVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLT 1101 V E + Q KLE + E Q + +Q+L EL+ + RE ++ ++ ++ Sbjct: 914 QVQMLEQERNQSLMKLEESDRERQGLKQQILILNNTKVELENIRREYENFKQKYEQL--- 970 Query: 1102 FEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQS 1161 E + + ++ +++ D ++ +++ E + RS LQ S Sbjct: 971 ------DRETISLRQQLQILNNQKGEFDRIKVEYSQLKINVE-EQDREHLSLRSQLQLAS 1023 Query: 1162 AKLN--TELQECYTKIIQLETLNTELTGHDVVNQEQ-----INQLKSKLEQLNTENDNLL 1214 + N + ++ Y II+++ +E + V +Q Q IN K ++E LN + Sbjct: 1024 NQKNDLEKFRQEY-DIIRIKLEESEKDKNQVKSQLQVYITNINAYKDQIEHLNIQ----- 1077 Query: 1215 STVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLD- 1273 +++ + +SS Q E+ + L Q+ F+K + + Q+ F+ KY+++L Sbjct: 1078 --ISQFQQDLSSFQQQEIMMKREI--EMLIQQIDIFKKDQQNKQQQIQEFQFKYQEILRE 1133 Query: 1274 -SVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIE-ILRSEIEDEK 1331 V S Q + M ++ L+ +L KE+ +++Y + Q E ++ +E E Sbjct: 1134 YEVLQSKQVNIDVDALMYEIFELKKQLVQKEKQYEIERQEYLEQKFQSEKNIKLRVEQE- 1192 Query: 1332 VAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXX 1391 ++ E Q Q++ + L ++ L+K Sbjct: 1193 --IRQITERYNFEREELRKQIQVEKQQKLQIETELRLKYEQQILILQK-QIKPVIDVDAL 1249 Query: 1392 XXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRI 1448 + + + +V+ QLE E YQ + Q+ +FE+ + +E E R+ Sbjct: 1250 MYDIFELKKQVVAKDQQLEQLKKEQYQMRLQIEQQFNQQRMKFESELRVKLERELRM 1306 Score = 105 bits (253), Expect = 8e-21 Identities = 189/967 (19%), Positives = 396/967 (40%), Gaps = 85/967 (8%) Query: 682 IENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEK--ISELLAKI 739 I+ L+ L + + + +D + Q N + + E++ +K I L + Sbjct: 40 IQQLQAQLHYLNQKVPEFQQIFKDNQQMKKALDQMNQSVKEYEEEIQRQKQIIDRLNLDL 99 Query: 740 NHEEQSKIQTQFGIDAKIQERDLYIE-NIESELSKYKSRICRLEESIAVMEDRRYSLERK 798 + ++ Q G + I+ R L E N++ + + K I L + ++ Y L R Sbjct: 100 DKAKRDNEQLLQGFN-DIKHRGLSQEQNLQQDNQRMKHTIDGLNNDLRNLQQEVYRL-RS 157 Query: 799 ADQLGSYLQEKQKAYSEYTIQEDELVNRLAV-LMDHDRVVEKQLLEIEHENKELQKKNQI 857 + Y+QE+ Y + Q + +L + + D + +++I + +N I Sbjct: 158 LNDKSKYVQEESYHYQQENQQYLAKIRQLEMQIRDLMSKEDNYIMQINKAAQGNNNENMI 217 Query: 858 LLEENQNLQISLSDMQQHYNALVEKAN--RTDLAESESTKYQTQLRD-LESNLKRITHEH 914 L E+N LQ L +Q+ Y +E + R + + Q++D L ++ +E Sbjct: 218 LKEQNAQLQQQLLQLQKQYQKQLEDMSQERDKILSDQRNTINIQIKDQLLREQQKWQNER 277 Query: 915 QTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLE---AQLQEYKNNI 971 + L+ +EI+ L+ + + + +R ++ + E+ +N +Y+ +LE QLQ + Sbjct: 278 EALL----QEIQLLKQQLSQNEQQILRKRQQIEEEVNRNQQYLIELEQGNTQLQNRCREL 333 Query: 972 ENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIA---L 1028 +N +++ E +K ++ + + +QQ Q Q + NK N LL+Q +++ L Sbjct: 334 QN-QISLMEKDKHRIDQYTRRIDEQQQQLDQLQRQMYDLTNKYNNLLQQYEQKKYQNEQL 392 Query: 1029 NQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVS-----------------KQL 1071 N ++N Q + + E ++ + +L + + Q+++ KQL Sbjct: 393 NSQLNMVQEHDKQKIINLEKQIRELQDQLADTQRLRQQLNQMNENYTALQLSFKTSQKQL 452 Query: 1072 LDSKQHNEELQILVRE------QDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMS--D 1123 D + N+EL L RE QD + K+ + + + I + +S +E + + Sbjct: 453 QDFDELNQELIQLQRELEYYKQQDVKNKQDLDQYKSQLLMIENRQNQQANSELEKLKYQN 512 Query: 1124 DANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNT 1183 N + K Q+ + +Q ++ +S +L +++E + Q++ Sbjct: 513 QQLNDELNNLRNTNQQLTFKFQQAQNDLQSQNYALNESNQLKAKIKEL---LDQIQYQQI 569 Query: 1184 ELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAE--LWKQ 1241 E+ D + QE L+ KL+Q N + D L+ T+ + R + Q ++A+ L+K Sbjct: 570 EINKKDKLIQE----LQIKLQQQNQKID-LIITMEKERKDFEYRIIQLEKQLADSNLYKS 624 Query: 1242 HLAQREADFQ--KTEHEL-RVQLSAFESKYE-------QLLDSVQSSTQ--EETNKIVTM 1289 + ++ ++ + ++EL R++L + + + QL D+ TQ E NK + Sbjct: 625 QFIELQSKYENLRKDYELLRIKLEEYNNMQQKMVWLEKQLADANIYKTQYLELENKYNNL 684 Query: 1290 E-----QVTSLQNKLQDKEEH---LRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXX 1341 + +++ L+ +LQ+ + LQ KY +I + EI++ + E + Sbjct: 685 DANYQFKISQLEKQLQEANMYKMQYAELQNKYNFIIQENEIVKKDYEQLRYKLEEVNNQL 744 Query: 1342 XXXXXXXXXDLRTENQSYKQMQEQSILNIN--EENAQLKKSSXXXXXXXXXXXXRVNDAE 1399 TE + K + IL E +S+ V Sbjct: 745 IISKKQITIQFNTEFDALKSEMQTWILKCKTYENEINFLRSTIKDYQDNDNENLLVKKEL 804 Query: 1400 AKVLELTHQLELKDSEIYQKTHEYTITLTQRND---EFENVRQQLVEYEKRIEDLTYEKE 1456 + +LE + ++ E + ND + +N + ++ EK D T ++ Sbjct: 805 ERWQIKCSELERERQQLKLNLQELDKLRYRINDLEKDNQNYQFKIARLEKEA-DATRQQI 863 Query: 1457 SELAILRLKMHENANHYETMQ---KESEIERVKLIEELNVKITESVSLNKQVAELNKALE 1513 L R + Y+ +Q +E E E+ +L E+++ + QV L + Sbjct: 864 IILEQQRTQYDLIKKDYDALQIRLQEQEREKSQLRNEMDILRQQLQQFKSQVQMLEQERN 923 Query: 1514 EEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDE-QL 1572 + + K E + + +I+ LN+ L+N+ R + QK+ +T R + Q+ Sbjct: 924 QSLMKLEESDRERQGLKQQILILNNTKVELENIRREYENFKQKYEQLDRETISLRQQLQI 983 Query: 1573 DNTMNKE 1579 N E Sbjct: 984 LNNQKGE 990 Score = 84.2 bits (199), Expect = 3e-14 Identities = 112/571 (19%), Positives = 254/571 (44%), Gaps = 46/571 (8%) Query: 534 KLKLKQMQKTIDNFSKVSDSNK----EIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYD 589 KL L+++ K + + N+ +I RL +E Q++ LE+++ L DYD Sbjct: 822 KLNLQELDKLRYRINDLEKDNQNYQFKIARLEKEADATRQQIIILEQQRTQYDLIKKDYD 881 Query: 590 SGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQ 649 + ++ + ++ ++ N + + + +SQ L QE + K +E + + + Q Sbjct: 882 ALQIRLQEQEREKSQLRNEMDILRQQLQQFKSQVQMLEQERNQSLMKLEESDRERQGLKQ 941 Query: 650 --LQSDQVCSEIKSVHLE--------EQIDALSASKKELALVIENLKLDKEQL---YGTI 696 L + E++++ E EQ+D + S ++ ++ N K + +++ Y + Sbjct: 942 QILILNNTKVELENIRREYENFKQKYEQLDRETISLRQQLQILNNQKGEFDRIKVEYSQL 1001 Query: 697 KDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAK 756 K +++ L++ +Q + + LEK E + K+ E+ K Q + + Sbjct: 1002 KINVEEQDREHLSLRSQLQLASNQKNDLEKFRQE-YDIIRIKLEESEKDKNQVKSQLQVY 1060 Query: 757 IQERDLY---IENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAY 813 I + Y IE++ ++S+++ + ++ +M+ L ++ D Q KQ+ Sbjct: 1061 ITNINAYKDQIEHLNIQISQFQQDLSSFQQQEIMMKREIEMLIQQIDIFKKDQQNKQQQI 1120 Query: 814 SEYTIQEDELVNRLAVLMDHDRVVEKQLL--EIEHENKEL-QKKNQILLEENQNLQISLS 870 E+ + E++ VL ++ L EI K+L QK+ Q +E + L+ Sbjct: 1121 QEFQFKYQEILREYEVLQSKQVNIDVDALMYEIFELKKQLVQKEKQYEIERQEYLEQKFQ 1180 Query: 871 D-------MQQHYNALVEKAN--RTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQK 921 ++Q + E+ N R +L + + Q +L+ +E+ L R+ +E Q LI+QK Sbjct: 1181 SEKNIKLRVEQEIRQITERYNFEREELRKQIQVEKQQKLQ-IETEL-RLKYEQQILILQK 1238 Query: 922 K-KEIEDLEI----EFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIEN-LN 975 + K + D++ F + + +D++ L + ++ + Q+E Q + + E+ L Sbjct: 1239 QIKPVIDVDALMYDIFELKKQVVAKDQQ-LEQLKKEQYQMRLQIEQQFNQQRMKFESELR 1297 Query: 976 MNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNA 1035 + +E +M++E + + + + YI ++ K ++ + +DEEI + Sbjct: 1298 VKLERELRMSIESEIRFQIENDYKFDQNIQDYILQVEKWKSVCQMRDEEI----DHMRGL 1353 Query: 1036 QVSYMSMVSDYESKLAQFTTKLENMEEEMQR 1066 Q + ++ Y ++ T+L + E ++ Sbjct: 1354 QQALKEKLNQYTQEIESLKTQLSMFQGERKK 1384 >UniRef50_UPI0000E476CA Cluster: PREDICTED: similar to KIAA0445 protein; n=6; Deuterostomia|Rep: PREDICTED: similar to KIAA0445 protein - Strongylocentrotus purpuratus Length = 2435 Score = 136 bits (329), Expect = 5e-30 Identities = 255/1263 (20%), Positives = 527/1263 (41%), Gaps = 113/1263 (8%) Query: 358 AVSSPSKKGSPLISRKSGRNTAS--KMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQ 415 +++SP K +PL R TAS + +SP S+ + Q +K + ++ +L+ + Sbjct: 499 SLASPYAKSTPLRPVTPSRRTASPSRARSPGFPDSTYSAVQAALQK-RQLQVQELKARLN 557 Query: 416 SLNKDL--VDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTE 473 S + K SE + + ++Q QLE + + + E Sbjct: 558 STRDQASTLKKNLEGSENERRQTERAVDAHRDNLSVSQRQLEEIKRDRD----RLRNSLE 613 Query: 474 DVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNH 533 E L+Q LN +I+ +NV++ E+L++A + + D ++ ++ K Sbjct: 614 ATGSEKSGLENLRQSLNAQIESLNVEN--ERLQAANSDLQRQRDHLEDEREDREKDSIRQ 671 Query: 534 KLKLKQMQKTIDNFS-KVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGR 592 K ++++ K ++ K S+ ++IV L E L+ + LE+EK + L + R Sbjct: 672 KKEIERSHKLLEQMEGKNSNLKEDIVTLKEALNKAVLEKDVLEQEKAEISESLARLEVQR 731 Query: 593 M-IESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQ 651 +E ++ + E L ++ LK +L E D ++ I+ Q E + D + Sbjct: 732 AELEVELNRLRTEEAGLRDSLLKMQALNEGLGQDKIELNKIIMQLEAEKNRLIEDKDNIH 791 Query: 652 SDQVCSEIKSVHLE-EQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKL 710 ++ + + +E E++D E K+ Q ++D E+ M+ L Sbjct: 792 HERAAIRDELMRVESEKVDT------------ETEKMGLNQSLSLMEDNRTRLEEEMSLL 839 Query: 711 QNYIQENMDLTDKLEKMSAEK--ISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIE 768 +E +L D L ++S +K ++E L + + + +I+ I + +E + Sbjct: 840 N---REKGELGDNLSQLSRQKNSLAEELLQTRRDVERQIEAVTRIAKEKEELTKEKAELI 896 Query: 769 SELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDEL----V 824 +L+ + E IA M + SLER L Y Q K ++ T E EL V Sbjct: 897 VQLTASERENRAQAEVIAAMNTDKESLERT---LYEYQQSLAKLEAKRTQLESELQEQGV 953 Query: 825 NRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKAN 884 ++ V ++ R ++ +E+ K+L+ NQ ++++ ++ Q++L QQ ++ VE+ N Sbjct: 954 SKEGVTVELARQRKEMEIEMTRYQKDLELLNQRMVQQERDTQLALKQRQQAHDEDVERLN 1013 Query: 885 RTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKK 944 R ++ES + + Q +LE L R+ E L D ++ E +DK Sbjct: 1014 RERVSES-LARLEVQRAELEVELNRLRTEEAGL--------RDSLLKMQALNEGLGQDKI 1064 Query: 945 VLNEKYEKNIEYVTQLEAQ---LQEYKNNIENLNMNV-EELNKMNLELIDKHVQKQQTQS 1000 LN + + QLEA+ L E K+NI + + +EL ++ E +D +K Sbjct: 1065 ELN-------KIIMQLEAEKNRLIEDKDNIHHERAAIRDELMRVESEKVDTETEKMGLNQ 1117 Query: 1001 PDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENM 1060 + E N+ + +EE+ LN++ + L+Q + + ++ Sbjct: 1118 ----SLSLMEDNR-----TRLEEEMSLLNRE-----------KGELGDNLSQLSRQKNSL 1157 Query: 1061 EEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEP 1120 EE+ + + D ++ E + + +E+++ KE + +L ++ + E + I Sbjct: 1158 AEELLQTRR---DVERQIEAVTRIAKEKEELTKE--KAELIVQLTASERENRAQAEVIAA 1212 Query: 1121 MSDDANNVDXXXXXXXXXXXXLKVQ--EEEEFIQERSVLQE-QSAKLNTELQECYTKIIQ 1177 M+ D +++ L+ + + E +QE+ V +E + +L + +E ++ + Sbjct: 1213 MNTDKESLERTLYEYQQSLAKLEAKRTQLESELQEQGVSKEGVTVELARQRKEMEIEMTR 1272 Query: 1178 LETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAE 1237 + + EL +V QE+ QL L+Q +D + + R S+ A++ ++ Sbjct: 1273 YQK-DLELLNQRMVQQERDTQL--ALKQRQQAHDEDVERLNRERESLKLAMEAEKEDLVR 1329 Query: 1238 LWKQHLAQREADFQKTEHELRVQLSAFESKYEQLL-----DSVQSSTQEETNKIVTMEQV 1292 Q + + + + EL L + + ++ L D QS + +T + +E++ Sbjct: 1330 KTNQEREELNGRYMQEKEELTEDLMGLQRERDESLLLAENDKQQSLSLAQTERNQLVEKL 1389 Query: 1293 TSLQNKLQDKEEHL-RNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXD 1351 S Q + + + R +E + E +R +++DE D Sbjct: 1390 NSSQRDMANASMEMDRIKREAFTRAETDKEAIR-DVQDELKELRARFEEGTNVRERQAKD 1448 Query: 1352 LRTENQSYKQMQEQSILNINEENAQLK---KSSXXXXXXXXXXXXRVNDA-EAKVLELTH 1407 L + + ++++E + +NE QLK +S ++ + E + ++ Sbjct: 1449 LSNQIKDLQKVKEALLREVNELKTQLKMAEESRDGVRRELIEAHRKIREGDEGREIQRKE 1508 Query: 1408 QLELK---DSEIYQK--THEYTITLTQRNDEFENVRQQL-VEYEKRIEDLTYEKESELAI 1461 +ELK + E+ +K + L Q+ + E R QL E+R + + +ES+ AI Sbjct: 1509 NMELKRQMNDEVREKDAINRANEELRQKVKKVETDRIQLNRNVEERTQKIAVLEESKTAI 1568 Query: 1462 LRL--KMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNK--ALEEEVA 1517 + + + E + E+ E +L ++ T+ L K + +L A ++E Sbjct: 1569 QKEAGDLRASLREVEKSRLEARRELQELRRQVKTLDTDKAKLTKDIHDLQNRVARDDEKE 1628 Query: 1518 KTNEMQT-ALENQEI--EIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDN 1574 + N + AL+ + + L +L+ +R V A ++ E+L Sbjct: 1629 EENRKEIYALKQKSARKDAQNLTRRFGDLEEELRLKEKDYAMSVDEARSAERRISERLRT 1688 Query: 1575 TMN 1577 T N Sbjct: 1689 TEN 1691 Score = 122 bits (294), Expect = 8e-26 Identities = 219/1072 (20%), Positives = 468/1072 (43%), Gaps = 97/1072 (9%) Query: 297 KQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTES 356 + S+E + EK+ +E A + L + E L+ N +++ LE++ +S Sbjct: 609 RNSLEATGSEKSGLENLRQSLNAQIESLNVENERLQAANSDLQRQRDHLEDEREDREKDS 668 Query: 357 KAVSSPSKKGSPLISRKSGRNTASK-----MKSPWSQ--LSSETLNQ---DTDKKINKNE 406 ++ L+ + G+N+ K +K ++ L + L Q + + + + E Sbjct: 669 IRQKKEIERSHKLLEQMEGKNSNLKEDIVTLKEALNKAVLEKDVLEQEKAEISESLARLE 728 Query: 407 I--AKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPS 464 + A+LE+ + L + + + + +I QL+ E + +E Sbjct: 729 VQRAELEVELNRLRTEEAGLRDSLLKMQALNEGLGQDKIELNKIIMQLEAEKNRLIEDKD 788 Query: 465 LIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVK-DLIEKLKSAEEQITQLNDEIDAAN 523 IH +E A ++++L + ++++ K L + L E+ T+L +E+ N Sbjct: 789 NIH--------HERAAIRDELMRVESEKVDTETEKMGLNQSLSLMEDNRTRLEEEMSLLN 840 Query: 524 KNMIKVKSNHKLKLKQMQKTIDNFS-KVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQ 582 + ++ N L Q+ + ++ + ++ + +++ R E + ++++ EL +EK L Sbjct: 841 REKGELGDN----LSQLSRQKNSLAEELLQTRRDVERQIEAVTRIAKEKEELTKEKAELI 896 Query: 583 LHLVDYDSGRMIESDVYKKM-IEMENLAETRL---KAISLLESQKFDLVQELHILQQKYD 638 + L + +++V M + E+L T ++++ LE+++ L EL + Sbjct: 897 VQLTASERENRAQAEVIAAMNTDKESLERTLYEYQQSLAKLEAKRTQLESELQEQGVSKE 956 Query: 639 EVEDKLA--------DISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKE 690 V +LA ++++ Q D + V +E+ L+ +++ A + +L++E Sbjct: 957 GVTVELARQRKEMEIEMTRYQKDLELLNQRMVQ-QERDTQLALKQRQQAHDEDVERLNRE 1015 Query: 691 QLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSA-------EKI--SELLAKINH 741 ++ ++ LE + ++ +L E L D L KM A +KI ++++ ++ Sbjct: 1016 RVSESLARLEVQRAELEVELNRLRTEEAGLRDSLLKMQALNEGLGQDKIELNKIIMQLEA 1075 Query: 742 EEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQ 801 E+ I+ + I + + +ESE ++ L +S+++MED R LE + Sbjct: 1076 EKNRLIEDKDNIHHERAAIRDELMRVESEKVDTETEKMGLNQSLSLMEDNRTRLEEEMSL 1135 Query: 802 LGSYLQEKQKAYSEYTIQEDELVNR-LAVLMDHDRVVEKQLLEIEHENKELQKKNQILLE 860 L E S+ + Q++ L L D +R +E + I E +EL K+ L+ Sbjct: 1136 LNREKGELGDNLSQLSRQKNSLAEELLQTRRDVERQIE-AVTRIAKEKEELTKEKAELI- 1193 Query: 861 ENQNLQISLSDMQQHYNALVEKANRTDLAESEST--KYQTQLRDLESNLKRITHEHQTLI 918 +Q++ S+ + A V A TD E T +YQ L LE+ ++ E Q Sbjct: 1194 ----VQLTASERENRAQAEVIAAMNTDKESLERTLYEYQQSLAKLEAKRTQLESELQEQG 1249 Query: 919 VQKK---KEIEDLEIEFNTQIESAIRDKKVLNEK-YEKNIEYVTQLEAQLQEYKNNIENL 974 V K+ E+ E ++ +D ++LN++ ++ + L+ + Q + ++E L Sbjct: 1250 VSKEGVTVELARQRKEMEIEMTRYQKDLELLNQRMVQQERDTQLALKQRQQAHDEDVERL 1309 Query: 975 NMNVEELNKMNLE-----LIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEE-IIAL 1028 N E L K+ +E L+ K Q+++ + Y ++ L L +++DE ++A Sbjct: 1310 NRERESL-KLAMEAEKEDLVRKTNQEREELNGRYMQEKEELTEDLMGLQRERDESLLLAE 1368 Query: 1029 NQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQ 1088 N K + ++ + KL + N EM R+ ++ + ++E +R+ Sbjct: 1369 NDKQQSLSLAQTER-NQLVEKLNSSQRDMANASMEMDRIKREAFTRAETDKE---AIRDV 1424 Query: 1089 DDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEE 1148 D++KEL+ + N+ + + +S+ I+ D V ++E Sbjct: 1425 QDELKELR-ARFEEGTNVRERQAKDLSNQIK----DLQKVKEAL-----------LREVN 1468 Query: 1149 EFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNT 1208 E + + +E + EL E + KI + + ++ + Q+N + + +N Sbjct: 1469 ELKTQLKMAEESRDGVRRELIEAHRKIREGDEGREIQRKENMELKRQMNDEVREKDAINR 1528 Query: 1209 ENDNLLSTVAEL---RSSISSAVDQRGFEIAELWKQHLA-QREA-DFQKTEHELRVQLSA 1263 N+ L V ++ R ++ V++R +IA L + A Q+EA D + + E V+ S Sbjct: 1529 ANEELRQKVKKVETDRIQLNRNVEERTQKIAVLEESKTAIQKEAGDLRASLRE--VEKSR 1586 Query: 1264 FESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKL-QDKEEHLRNLQEKYA 1314 E++ E L + + +T+K + + LQN++ +D E+ N +E YA Sbjct: 1587 LEARRE-LQELRRQVKTLDTDKAKLTKDIHDLQNRVARDDEKEEENRKEIYA 1637 Score = 115 bits (277), Expect = 9e-24 Identities = 185/1031 (17%), Positives = 429/1031 (41%), Gaps = 76/1031 (7%) Query: 619 LESQKFDLVQEL-HILQQKYDEVEDKLADISQLQ-SDQVCSEI--KSVHLEEQIDALSAS 674 L++ DL ++ H+ ++ D +D + +++ S ++ ++ K+ +L+E I L + Sbjct: 643 LQAANSDLQRQRDHLEDEREDREKDSIRQKKEIERSHKLLEQMEGKNSNLKEDIVTLKEA 702 Query: 675 KKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSA----- 729 + L + L+ +K ++ ++ LE + ++ +L E L D L KM A Sbjct: 703 LNKAVLEKDVLEQEKAEISESLARLEVQRAELEVELNRLRTEEAGLRDSLLKMQALNEGL 762 Query: 730 --EKI--SELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESI 785 +KI ++++ ++ E+ I+ + I + + +ESE ++ L +S+ Sbjct: 763 GQDKIELNKIIMQLEAEKNRLIEDKDNIHHERAAIRDELMRVESEKVDTETEKMGLNQSL 822 Query: 786 AVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLA-VLMDHDRVVEKQLLEI 844 ++MED R LE + L E S+ + Q++ L L D +R +E + I Sbjct: 823 SLMEDNRTRLEEEMSLLNREKGELGDNLSQLSRQKNSLAEELLQTRRDVERQIEA-VTRI 881 Query: 845 EHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESEST--KYQTQLRD 902 E +EL K+ L+ +Q++ S+ + A V A TD E T +YQ L Sbjct: 882 AKEKEELTKEKAELI-----VQLTASERENRAQAEVIAAMNTDKESLERTLYEYQQSLAK 936 Query: 903 LESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEA 962 LE+ ++ E Q V K E + +E Q ++ ++ +Y+K++E + Q Sbjct: 937 LEAKRTQLESELQEQGVSK----EGVTVELARQR----KEMEIEMTRYQKDLELLNQRMV 988 Query: 963 QLQEYKNNI---ENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLK 1019 Q QE + + + E++ ++N E + + + + + Q + E +N + A L+ Sbjct: 989 Q-QERDTQLALKQRQQAHDEDVERLNRERVSESLARLEVQRAEL-EVELNRLRTEEAGLR 1046 Query: 1020 QKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLL--DSKQH 1077 ++ ALN+ + ++ ++ E++ + +N+ E + +L+ +S++ Sbjct: 1047 DSLLKMQALNEGLGQDKIELNKIIMQLEAEKNRLIEDKDNIHHERAAIRDELMRVESEKV 1106 Query: 1078 NEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXX 1137 + E + + Q + E T+L EM++ E + + +S N++ Sbjct: 1107 DTETEKMGLNQSLSLMEDNRTRLEEEMSLLNREKGELGDNLSQLSRQKNSL-AEELLQTR 1165 Query: 1138 XXXXLKVQEEEEFIQERSVLQEQSAKLNTEL------QECYTKIIQLETLNTELTGHDVV 1191 +++ +E+ L ++ A+L +L ++I + E + Sbjct: 1166 RDVERQIEAVTRIAKEKEELTKEKAELIVQLTASERENRAQAEVIAAMNTDKESLERTLY 1225 Query: 1192 NQEQI--------NQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHL 1243 +Q QL+S+L++ + + +A R + + + ++ EL Q + Sbjct: 1226 EYQQSLAKLEAKRTQLESELQEQGVSKEGVTVELARQRKEMEIEMTRYQKDL-ELLNQRM 1284 Query: 1244 AQREADFQKTEHELRVQLSAFESKYEQL---LDSVQSSTQEETNKIV--TMEQVTSLQNK 1298 Q+E D T+ L+ + A + E+L +S++ + + E +V T ++ L + Sbjct: 1285 VQQERD---TQLALKQRQQAHDEDVERLNRERESLKLAMEAEKEDLVRKTNQEREELNGR 1341 Query: 1299 -LQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQ 1357 +Q+KEE +L + + + ++ + D+ + Sbjct: 1342 YMQEKEELTEDLMGLQRERDESLLLAENDKQQSLSLAQTERNQLVEKLNSSQRDMANASM 1401 Query: 1358 SYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQ---LELKDS 1414 +++ ++ + ++ N E + +L++Q L+ Sbjct: 1402 EMDRIKREAFTRAETDKEAIRDVQDELKELRARFEEGTNVRERQAKDLSNQIKDLQKVKE 1461 Query: 1415 EIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKE---SELAILRLKMHENAN 1471 + ++ +E L + + VR++L+E ++I + +E E L+ +M++ Sbjct: 1462 ALLREVNELKTQLKMAEESRDGVRRELIEAHRKIREGDEGREIQRKENMELKRQMNDEVR 1521 Query: 1472 HYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEI 1531 + + + +E R K ++++ T+ + LN+ V E +++A E +TA++ + Sbjct: 1522 EKDAINRANEELRQK-VKKVE---TDRIQLNRNVEERT----QKIAVLEESKTAIQKEAG 1573 Query: 1532 EIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDL 1591 ++ E+ + R ++++ V K + + + N+ D E Sbjct: 1574 DLRASLREVEKSRLEARRELQELRRQVKTLDTDKAKLTKDIHDLQNRVARDDEKEEENRK 1633 Query: 1592 AMYMLHQRDVR 1602 +Y L Q+ R Sbjct: 1634 EIYALKQKSAR 1644 Score = 113 bits (272), Expect = 4e-23 Identities = 191/972 (19%), Positives = 402/972 (41%), Gaps = 67/972 (6%) Query: 669 DALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMS 728 D LS S+++L E +K D+++L +++ ++K + N Q+ + L + E++ Sbjct: 589 DNLSVSQRQL----EEIKRDRDRLRNSLEATGSEKSGLENLRQSLNAQIESLNVENERLQ 644 Query: 729 AEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVM 788 A S+L + +H E + + D+ Q+++ IE L + + + L+E I + Sbjct: 645 AAN-SDLQRQRDHLEDEREDREK--DSIRQKKE--IERSHKLLEQMEGKNSNLKEDIVTL 699 Query: 789 EDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHEN 848 ++ + D L E ++ + +Q EL L L + + LL+++ N Sbjct: 700 KEALNKAVLEKDVLEQEKAEISESLARLEVQRAELEVELNRLRTEEAGLRDSLLKMQALN 759 Query: 849 KEL-QKK---NQIL--LEENQNLQISLSDMQQHYNALVE------KANRTDLAESESTKY 896 + L Q K N+I+ LE +N I D H A + ++ + D E+E Sbjct: 760 EGLGQDKIELNKIIMQLEAEKNRLIEDKDNIHHERAAIRDELMRVESEKVD-TETEKMGL 818 Query: 897 QTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEY 956 L +E N R+ E +L+ ++K E+ D + + Q S + E+ IE Sbjct: 819 NQSLSLMEDNRTRL-EEEMSLLNREKGELGDNLSQLSRQKNSLAEELLQTRRDVERQIEA 877 Query: 957 VTQLEAQLQEYKNNIENLNMNV---EELNKMNLELIDK-HVQKQQTQSPDYTEQYINEIN 1012 VT++ + +E L + + E N+ E+I + K+ + Y +Y + Sbjct: 878 VTRIAKEKEELTKEKAELIVQLTASERENRAQAEVIAAMNTDKESLERTLY--EYQQSLA 935 Query: 1013 KLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEM---QRVSK 1069 KL A Q + E+ V + E ++ ++ LE + + M +R ++ Sbjct: 936 KLEAKRTQLESELQEQGVSKEGVTVELARQRKEMEIEMTRYQKDLELLNQRMVQQERDTQ 995 Query: 1070 QLLDSKQ--HNEELQILVREQDDQIK---ELKETKLTFEMNIPKTEGMIISSTIEPMSDD 1124 L +Q H+E+++ L RE+ + E++ +L E+N +TE + ++ M Sbjct: 996 LALKQRQQAHDEDVERLNRERVSESLARLEVQRAELEVELNRLRTEEAGLRDSLLKMQAL 1055 Query: 1125 ANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTE 1184 + L+ E+ I+++ + + A + EL ++ + ET Sbjct: 1056 NEGLGQDKIELNKIIMQLEA-EKNRLIEDKDNIHHERAAIRDELMRVESEKVDTETEKMG 1114 Query: 1185 LTGHDVVNQEQINQLKSKLEQLNTENDNL---LSTVAELRSSISSAVDQRGFEIAELWKQ 1241 L + ++ +L+ ++ LN E L LS ++ ++S++ + Q ++ + Sbjct: 1115 LNQSLSLMEDNRTRLEEEMSLLNREKGELGDNLSQLSRQKNSLAEELLQTRRDVERQIEA 1174 Query: 1242 --HLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKL 1299 +A+ + + K + EL VQL+A E + + + + ++ + T+ + KL Sbjct: 1175 VTRIAKEKEELTKEKAELIVQLTASERENRAQAEVIAAMNTDKESLERTLYEYQQSLAKL 1234 Query: 1300 QDKEEHLRN-LQEKYAD---VINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTE 1355 + K L + LQE+ V ++ R E+E E + D + Sbjct: 1235 EAKRTQLESELQEQGVSKEGVTVELARQRKEMEIEMTRYQKDLELLNQRMVQQERDTQLA 1294 Query: 1356 NQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDA-EAKVLELTHQLELKDS 1414 + +Q ++ + +N E LK + + + + ++ +L +D Sbjct: 1295 LKQRQQAHDEDVERLNRERESLKLAMEAEKEDLVRKTNQEREELNGRYMQEKEELT-EDL 1353 Query: 1415 EIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKM----HENA 1470 Q+ + ++ L + ND+ +++ E + +E L + ++A ++M E Sbjct: 1354 MGLQRERDESLLLAE-NDKQQSLSLAQTERNQLVEKLN-SSQRDMANASMEMDRIKREAF 1411 Query: 1471 NHYET-------MQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQ 1523 ET +Q E + R + E NV+ ++ L+ Q+ +L K E + + NE++ Sbjct: 1412 TRAETDKEAIRDVQDELKELRARFEEGTNVRERQAKDLSNQIKDLQKVKEALLREVNELK 1471 Query: 1524 TALENQEIEIVTLNDEITNLQNMVRASSS--KIQKHVSFASDTKQG---RDEQLDNTMNK 1578 T L+ E + E+ +R +IQ+ + + R++ N N+ Sbjct: 1472 TQLKMAEESRDGVRRELIEAHRKIREGDEGREIQRKENMELKRQMNDEVREKDAINRANE 1531 Query: 1579 ELLDAVPRAELD 1590 EL V + E D Sbjct: 1532 ELRQKVKKVETD 1543 Score = 91.5 bits (217), Expect = 2e-16 Identities = 181/907 (19%), Positives = 388/907 (42%), Gaps = 84/907 (9%) Query: 212 EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271 E K ++ + ++N A +DE R+ + + L ++ L+E R + E Sbjct: 777 EAEKNRLIEDKDNIHHERAAIRDELMRVESEKVDTETEKMGLNQSLSLMEDNRTRLEEEM 836 Query: 272 SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTK-KIEL 330 S L +E + LA++ ++ + + +IE + ELTK K EL Sbjct: 837 SLLNREKGELGDNLSQLSRQKNSLAEELLQTRRDVERQIEAVTRI-AKEKEELTKEKAEL 895 Query: 331 LEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLS 390 + L R+ + E +A M T+ +++ + + + +K+++ +QL Sbjct: 896 IVQLTASERENRAQAE-VIAAMNTDKESLER---------TLYEYQQSLAKLEAKRTQLE 945 Query: 391 SETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIA 450 SE Q K E +E+ Q ++ Y +KD +DT +A Sbjct: 946 SELQEQGVSK-----EGVTVELARQRKEMEIEMTRY---QKDLELLNQRMVQQERDTQLA 997 Query: 451 QLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELND-EIKDVNVKDLIEKLKSAE 509 L+ Q H E ++ +E + + + +L+ ELN ++ ++D + K+++ Sbjct: 998 -LKQRQQAHDEDVERLNRERVSESLARLEVQRAELEVELNRLRTEEAGLRDSLLKMQALN 1056 Query: 510 EQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQ 569 E + Q D+I+ NK ++++++ ++ + + D E++R+ S+ Sbjct: 1057 EGLGQ--DKIE-LNKIIMQLEAEKNRLIEDKDNIHHERAAIRD---ELMRVE------SE 1104 Query: 570 KVAELEEEKG-NLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQ 628 KV E+ G N L L++ D+ +E ++ E L + +S L QK L + Sbjct: 1105 KVDTETEKMGLNQSLSLME-DNRTRLEEEMSLLNREKGELGDN----LSQLSRQKNSLAE 1159 Query: 629 ELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLD 688 EL LQ + D VE ++ ++++ ++ + L Q+ A + A VI + D Sbjct: 1160 EL--LQTRRD-VERQIEAVTRIAKEKEELTKEKAELIVQLTASERENRAQAEVIAAMNTD 1216 Query: 689 KEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQ 748 KE L T+ + + + K E + + +S E ++ LA+ E + ++ Sbjct: 1217 KESLERTLYEYQQSLAKLEAKRTQLESELQE-----QGVSKEGVTVELARQRKEMEIEM- 1270 Query: 749 TQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLE-----RKADQLG 803 T++ D ++ + + + +++L+ K R +E + + R SL+ K D + Sbjct: 1271 TRYQKDLELLNQRMVQQERDTQLA-LKQRQQAHDEDVERLNRERESLKLAMEAEKEDLVR 1329 Query: 804 SYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQ 863 QE+++ Y +++EL LM R ++ LL EN + Q + E NQ Sbjct: 1330 KTNQEREELNGRYMQEKEELTED---LMGLQRERDESLLLA--ENDKQQSLSLAQTERNQ 1384 Query: 864 NLQISLSDMQQHYNALVE--KANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQK 921 ++ S + NA +E + R +E+ K +RD++ LK + + + Sbjct: 1385 LVEKLNSSQRDMANASMEMDRIKREAFTRAETDK--EAIRDVQDELKELRARFEEGTNVR 1442 Query: 922 KKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEEL 981 +++ +DL + QI+ + K+ L + V +L+ QL+ + + + + + E Sbjct: 1443 ERQAKDL----SNQIKDLQKVKEAL-------LREVNELKTQLKMAEESRDGVRRELIEA 1491 Query: 982 NKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMS 1041 ++ + D+ + Q+ ++ + Q +E+ + +A+ + +E L QK+ + + Sbjct: 1492 HR-KIREGDEGREIQRKENMELKRQMNDEVREKDAINRANEE----LRQKVKKVETDRIQ 1546 Query: 1042 MVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLT 1101 + + E + T K+ +EE + K+ D + E++ E +++EL+ T Sbjct: 1547 LNRNVEER----TQKIAVLEESKTAIQKEAGDLRASLREVEKSRLEARRELQELRRQVKT 1602 Query: 1102 FEMNIPK 1108 + + K Sbjct: 1603 LDTDKAK 1609 Score = 78.2 bits (184), Expect = 2e-12 Identities = 159/887 (17%), Positives = 377/887 (42%), Gaps = 77/887 (8%) Query: 235 EKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXX 294 EK+ L K+ V++++ E N+ ++ + L + L + Sbjct: 884 EKEELTKEKAELIVQLTASERENRAQAEVIAAMNTDKESLERTLYEYQQSLAKLEAKRTQ 943 Query: 295 LAKQSIEPSC-EEKTEIE---EKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLA 350 L + E +E +E ++ +EI MT K +ELL R +E + +LA Sbjct: 944 LESELQEQGVSKEGVTVELARQRKEMEI-EMTRYQKDLELLNQ-----RMVQQERDTQLA 997 Query: 351 TMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKL 410 K + ++R+ + ++++ ++L E T++ ++ + K+ Sbjct: 998 L-----KQRQQAHDEDVERLNRERVSESLARLEVQRAELEVELNRLRTEEAGLRDSLLKM 1052 Query: 411 EMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGT 470 + + + L +D ++ +I + + KD + + + M S V T Sbjct: 1053 QALNEGLGQDKIELNKIIMQLEAEKNRLIED---KDNIHHERAAIRDELMRVESE-KVDT 1108 Query: 471 NTEDV--NEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIK 528 TE + N+ + E + L +E+ +N + + ++QL+ + ++ + +++ Sbjct: 1109 ETEKMGLNQSLSLMEDNRTRLEEEMSLLN-----REKGELGDNLSQLSRQKNSLAEELLQ 1163 Query: 529 VKSNHKLKLKQMQKTIDNFSKVSDSNKE-IVRLT---EELHHLSQKVAELEEEKGNLQLH 584 + + + +++ + + +++ E IV+LT E ++ +A + +K +L+ Sbjct: 1164 TRRDVERQIEAVTRIAKEKEELTKEKAELIVQLTASERENRAQAEVIAAMNTDKESLERT 1223 Query: 585 LVDYDSG-RMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDK 643 L +Y +E+ + E++ ++ L Q+ ++ E+ Q+ + + + Sbjct: 1224 LYEYQQSLAKLEAKRTQLESELQEQGVSKEGVTVELARQRKEMEIEMTRYQKDLELLNQR 1283 Query: 644 LADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDK 703 + + Q + Q+ + + +E ++ L+ ++ L L +E +KE L ++ ++ Sbjct: 1284 M--VQQERDTQLALKQRQQAHDEDVERLNRERESLKLAME---AEKEDL---VRKTNQER 1335 Query: 704 EDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSK--IQTQFG-IDAKIQER 760 E++ + Y+QE +LT+ L + E+ LL N ++QS QT+ + K+ Sbjct: 1336 EELNGR---YMQEKEELTEDLMGLQRERDESLLLAENDKQQSLSLAQTERNQLVEKLNSS 1392 Query: 761 DLYIENIESELSKYKSR-ICRLE---ESIAVMEDRRYSL-----------ERKADQLGSY 805 + N E+ + K R E E+I ++D L ER+A L + Sbjct: 1393 QRDMANASMEMDRIKREAFTRAETDKEAIRDVQDELKELRARFEEGTNVRERQAKDLSNQ 1452 Query: 806 LQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNL 865 +++ QK + +EL +L + + V ++L+E + +E + +I +EN L Sbjct: 1453 IKDLQKVKEALLREVNELKTQLKMAEESRDGVRRELIEAHRKIREGDEGREIQRKENMEL 1512 Query: 866 QISLSDMQQHYNALVEKAN---RTDLAESESTKYQTQLRDLESNLKRIT--HEHQTLIVQ 920 + ++D + +A + +AN R + + E+ + Q R++E ++I E +T I Sbjct: 1513 KRQMNDEVREKDA-INRANEELRQKVKKVETDRIQLN-RNVEERTQKIAVLEESKTAI-- 1568 Query: 921 KKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEE 980 +KE DL +S + ++ L E + ++ + +A+L + ++++N +E Sbjct: 1569 -QKEAGDLRASLREVEKSRLEARRELQE-LRRQVKTLDTDKAKLTKDIHDLQNRVARDDE 1626 Query: 981 LNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKD-----EEIIALNQKINNA 1035 + N + I QK + + ++ + LK+KD +E + ++I+ Sbjct: 1627 KEEENRKEIYALKQKSARKDAQNLTRRFGDLEE-ELRLKEKDYAMSVDEARSAERRISER 1685 Query: 1036 QVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQ 1082 + + + + ++ L KL E + + QL + +E++ Sbjct: 1686 LRTTENALDETKADLGDLKLKLSAAEGRVNGLESQLAQVEGAKQEVE 1732 Score = 66.1 bits (154), Expect = 8e-09 Identities = 84/395 (21%), Positives = 175/395 (44%), Gaps = 46/395 (11%) Query: 487 QELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDN 546 +E ++ ++ L+ +++ E + T L +D + ++ + + Q+Q Sbjct: 1982 KETESQVLQDRIEALMRQIQDLESKNTSLQLTVDRLSSSLARSEEGEHTLKDQLQSLS-- 2039 Query: 547 FSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEME 606 ++D+ E + E+LHHL Q VA E+++ LQ L D+ R SD K+ ++ Sbjct: 2040 -LSLNDTAMESTQKQEQLHHLQQAVANSEKDRRVLQERL---DAARHGASDAKKQNHQLI 2095 Query: 607 NLAETRLKAISLLESQKFDLVQEL----HILQQKYDEVEDKLADISQLQSDQVCSEIKSV 662 + ++ E ++ +L Q++ +++Q + E + I + Q+++ + Sbjct: 2096 ERVQQGQNDLAECELRRAELEQQVRSSQQLVKQHQESEETTMTQIQRFQAEKRSLKEHVT 2155 Query: 663 HLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDK----EDIM----------N 708 L++ L K+E+ L+ DK L T+ +E +K E +M Sbjct: 2156 TLQKAYSNLETEKREVQRSAGRLEKDKTALKKTLDKVEREKMRHEEAVMRATSEKGALDQ 2215 Query: 709 KLQNYIQENMDL---TDKL-------EKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQ 758 L + QEN++L T L E+ A+++ EL + H ++++I+T+ A++Q Sbjct: 2216 SLTSLDQENIELQRQTQALQATLAETEQQHAQRLIELTTR--HRQETEIETERLRTAQLQ 2273 Query: 759 ERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTI 818 +E+ ++ R+ LEE + ++D+ + RK Q Y+ K E Sbjct: 2274 AE----RTLEARERAHRQRVKGLEEQNSTLKDQMHHEVRKRQQ---YISMSSKTNDEIQD 2326 Query: 819 QEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQK 853 + L + L + D ++ LL EHE ++L + Sbjct: 2327 LRNMLSDSLHSVA-RDPTLDPLLL--EHETRKLDE 2358 Score = 62.5 bits (145), Expect = 9e-08 Identities = 86/454 (18%), Positives = 192/454 (42%), Gaps = 20/454 (4%) Query: 649 QLQSDQVC-SEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIM 707 +LQ D + SE ++E+I+ L S + N ++ + +E DK + Sbjct: 1889 KLQDDIIRRSERDRKGMQEKINTLERSLQSAEAEKRNQSDRIAKMNQGSQRMEGDKRSLR 1948 Query: 708 NKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENI 767 L+ L K + + L+ + E +S++ Q I+A +++ I+++ Sbjct: 1949 ETLEASENRCTQLELKRRALEGDLQRSHLSMNDKETESQV-LQDRIEALMRQ----IQDL 2003 Query: 768 ESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRL 827 ES+ + + + RL S+A E+ ++L+ + L L + ++ Q L + Sbjct: 2004 ESKNTSLQLTVDRLSSSLARSEEGEHTLKDQLQSLSLSLNDTAMESTQKQEQLHHLQQAV 2063 Query: 828 AVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTD 887 A RV++++L H + +K+N L+E Q Q L++ + L ++ + Sbjct: 2064 ANSEKDRRVLQERLDAARHGASDAKKQNHQLIERVQQGQNDLAECELRRAELEQQVRSSQ 2123 Query: 888 L-----AESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRD 942 ESE T TQ++ ++ KR EH T + + +E + E +D Sbjct: 2124 QLVKQHQESEETT-MTQIQRFQAE-KRSLKEHVTTLQKAYSNLETEKREVQRSAGRLEKD 2181 Query: 943 KKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPD 1002 K L + +K + E + + L+ ++ L++ N+EL + Q Q + Sbjct: 2182 KTALKKTLDKVEREKMRHEEAVMRATSEKGALDQSLTSLDQENIEL-QRQTQALQATLAE 2240 Query: 1003 YTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEE 1062 +Q+ + +L +Q+ E +++ AQ + E++ +++ +EE Sbjct: 2241 TEQQHAQRLIELTTRHRQETE---IETERLRTAQ---LQAERTLEARERAHRQRVKGLEE 2294 Query: 1063 EMQRVSKQLLDSKQHNEELQILVREQDDQIKELK 1096 + + Q+ + ++ + + +D+I++L+ Sbjct: 2295 QNSTLKDQMHHEVRKRQQYISMSSKTNDEIQDLR 2328 Score = 56.8 bits (131), Expect = 5e-06 Identities = 92/522 (17%), Positives = 222/522 (42%), Gaps = 49/522 (9%) Query: 483 EQLKQELNDEIKDVNVKDLIEKLKSAEEQ-----ITQLNDEIDAANKNMIKVKSNHKLK- 536 EQL +++ E + +KD ++LK E + +T+ + A+ ++ + KL+ Sbjct: 1833 EQLVADIDPETVRIALKDFSQQLKDTERERFQKSLTEAYEGKSGADGHLNNEHTALKLQD 1892 Query: 537 ---------LKQMQKTIDNFSK-VSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLV 586 K MQ+ I+ + + + E ++ + ++Q +E +K +L+ + Sbjct: 1893 DIIRRSERDRKGMQEKINTLERSLQSAEAEKRNQSDRIAKMNQGSQRMEGDKRSLR-ETL 1951 Query: 587 DYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLAD 646 + R + ++ ++ +E +L + L +++ E++ L + L ++ ++E K Sbjct: 1952 EASENRCTQLELKRRALE-GDLQRSHL-SMNDKETESQVLQDRIEALMRQIQDLESKNTS 2009 Query: 647 ----ISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLEND 702 + +L S SE L++Q+ +LS S + A+ + L + + E D Sbjct: 2010 LQLTVDRLSSSLARSEEGEHTLKDQLQSLSLSLNDTAMESTQKQEQLHHLQQAVANSEKD 2069 Query: 703 KEDIMNKL-------QNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDA 755 + + +L + ++N L +++++ + L + E+Q + Q Sbjct: 2070 RRVLQERLDAARHGASDAKKQNHQLIERVQQGQNDLAECELRRAELEQQVRSSQQLVKQH 2129 Query: 756 KIQERD--LYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAY 813 + E I+ ++E K + L+++ + +E + ++R A +L +K Sbjct: 2130 QESEETTMTQIQRFQAEKRSLKEHVTTLQKAYSNLETEKREVQRSAGRLEKDKTALKKTL 2189 Query: 814 SEYTIQEDELVNRLAVL--MDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSD 871 + ++ +++ + AV+ +++ L ++ EN ELQ+ + Q LQ +L++ Sbjct: 2190 DK--VEREKMRHEEAVMRATSEKGALDQSLTSLDQENIELQR-------QTQALQATLAE 2240 Query: 872 M-QQHYNALVEKANRTDLAESESTKYQTQ-LRDLESNLKRITHEHQTLIVQKKKEIEDLE 929 QQH L+E R + T+ +T+ LR + +R + Q+ K +E+ Sbjct: 2241 TEQQHAQRLIELTTR----HRQETEIETERLRTAQLQAERTLEARERAHRQRVKGLEEQN 2296 Query: 930 IEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNI 971 Q+ +R ++ K + + L L + +++ Sbjct: 2297 STLKDQMHHEVRKRQQYISMSSKTNDEIQDLRNMLSDSLHSV 2338 Score = 37.9 bits (84), Expect = 2.3 Identities = 58/301 (19%), Positives = 120/301 (39%), Gaps = 28/301 (9%) Query: 827 LAVLMDHDRVVEKQLLEIEH-------ENKELQKKNQIL---LEENQNLQISLSDMQQHY 876 L L + +R+++ +L +E + EL K Q L LE++ ++ Sbjct: 71 LGNLQEENRMLQNELSRVEDLLSSSRADRDELAIKYQALSDRLEQSYKADAGFEREREEQ 130 Query: 877 NALVEKAN---RTDLAESESTKYQTQLRDLESNLKR---ITHEHQTLIVQKKKEIEDLEI 930 N + N R L E E Y+ +L+ + +R + + Q ++Q K++ DLE Sbjct: 131 NRSLVSQNVELRRKL-EDEHGSYKRKLQAYQDGQQRQAQLVQKLQAKVLQYKRKCGDLES 189 Query: 931 EFNTQIESAIRDK---KVLNEKYEK-----NIEYVTQLEAQLQEYKNNI-ENLNMNVEEL 981 + + R+K +V E +E Q A L + + + E L+ E Sbjct: 190 SLQDSLNESDREKISMRVDEHATELEGTLIRLEEEQQRSASLAQVNSMLREQLDQATEAN 249 Query: 982 NKMNLEL--IDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSY 1039 +N E+ + V++ Q + ++ +E N + ++ L ++I + ++ Sbjct: 250 RSLNHEIDQLSNEVKRSQDDLDNRETEWRDEEKSFNEYFNSEHSRLLVLWRQIVAFRRNF 309 Query: 1040 MSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETK 1099 M S E L Q + + Q + L + Q +E ++ E++ K E++ Sbjct: 310 AEMKSSTERDLTQMRSDVTRTSRNTQSACQNLQSASQGSETGAVMALEREKGEKMQLESQ 369 Query: 1100 L 1100 + Sbjct: 370 M 370 Score = 37.5 bits (83), Expect = 3.0 Identities = 93/538 (17%), Positives = 202/538 (37%), Gaps = 36/538 (6%) Query: 1050 LAQFTTKLENMEEE-MQRVSKQLLDSKQ----HNEELQILVREQDDQIKELKETKLTFEM 1104 L F+ +L++ E E Q+ + + K H ++ QDD I+ + + + Sbjct: 1848 LKDFSQQLKDTERERFQKSLTEAYEGKSGADGHLNNEHTALKLQDDIIRRSERDRKGMQE 1907 Query: 1105 NIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSV-LQEQSAK 1163 I E + S+ E + ++E E + R L+ + Sbjct: 1908 KINTLERSLQSAEAEKRNQSDRIAKMNQGSQRMEGDKRSLRETLEASENRCTQLELKRRA 1967 Query: 1164 LNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSS 1223 L +LQ + + ET + L Q++I L +++ L ++N +L TV L SS Sbjct: 1968 LEGDLQRSHLSMNDKETESQVL-------QDRIEALMRQIQDLESKNTSLQLTVDRLSSS 2020 Query: 1224 ISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEET 1283 ++ + + +L L+ + + T+ K EQL Q+ E Sbjct: 2021 LARSEEGEHTLKDQLQSLSLSLNDTAMESTQ------------KQEQLHHLQQAVANSEK 2068 Query: 1284 NKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQI---EILRSEIEDEKVAFXXXXXX 1340 ++ V E++ + ++ D ++ L E+ N + E+ R+E+E + + Sbjct: 2069 DRRVLQERLDAARHGASDAKKQNHQLIERVQQGQNDLAECELRRAELEQQVRSSQQLVKQ 2128 Query: 1341 XXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEA 1400 ++ Q+ K+ ++ + + + + L+ + + A Sbjct: 2129 HQESEETTMTQIQ-RFQAEKRSLKEHVTTLQKAYSNLE-TEKREVQRSAGRLEKDKTALK 2186 Query: 1401 KVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELA 1460 K L+ + +++ E + L Q + +L + ++ E E + A Sbjct: 2187 KTLDKVEREKMRHEEAVMRATSEKGALDQSLTSLDQENIELQRQTQALQATLAETEQQHA 2246 Query: 1461 ILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLN--KQVAELNKALEEEVAK 1518 RL + ET + + +L E ++ E K + E N L++++ Sbjct: 2247 -QRLIELTTRHRQETEIETERLRTAQLQAERTLEARERAHRQRVKGLEEQNSTLKDQMH- 2304 Query: 1519 TNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTM 1576 +E++ + + T NDEI +L+NM+ S + + + + +LD +M Sbjct: 2305 -HEVRKRQQYISMSSKT-NDEIQDLRNMLSDSLHSVARDPTLDPLLLEHETRKLDESM 2360 >UniRef50_Q23QE6 Cluster: Guanylate-binding protein, N-terminal domain containing protein; n=1; Tetrahymena thermophila SB210|Rep: Guanylate-binding protein, N-terminal domain containing protein - Tetrahymena thermophila SB210 Length = 1697 Score = 136 bits (329), Expect = 5e-30 Identities = 246/1179 (20%), Positives = 491/1179 (41%), Gaps = 111/1179 (9%) Query: 475 VNEIAKVQEQLKQELNDEIKDVNVKDLIEKL---KSAEEQITQLND-EIDAANKNMIKVK 530 VN E L++ +N E ++ VK+L +++ +S ++ + N+ E+ K + Sbjct: 480 VNRNVIFLEFLQRSIN-EAANIFVKNLEQEVDIQRSCNSEVQRRNETELVELRKKTDNER 538 Query: 531 SNHKLKLKQMQKTIDNFSKVSDSNKEIVR-LTEELHHLSQKVAEL-EEEKGNLQLHLVDY 588 + K++Q+ K D+ + N+ V+ + EE + ++ EL E+ L + + Sbjct: 539 VLLERKVEQLLKEKDSIATDKVKNERAVKEIEEEKQKMEKEYKELLNSERVELNDQINNL 598 Query: 589 DSGRMIESDVYKKMIEMENLAETRL-KAISLLE--SQKFDLVQELHILQQKYDE--VEDK 643 + I + KK+ L E+ K +LLE +Q F+ + E ++ + K E ++ Sbjct: 599 RNKSKITEETLKKVERELLLKESSFQKEKALLEQRAQHFEKLCEEYLAKDKATENMMQST 658 Query: 644 LADIS-QLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLEND 702 + + Q++ Q E LE ++ L S EL I N + Q T++ E Sbjct: 659 HSGFNTQMKEQQTKYERIIKELENKLTNLKESNFELNEKISNQSQNFSQEVETLQTRERG 718 Query: 703 KEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDL 762 + +LQ I + + + +L + N+E D KIQ L Sbjct: 719 LLRQIEELQTEISSTKKQLSEASTNGLKNLGDLKEQFNNETN---------DLKIQNTQL 769 Query: 763 YIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDE 822 E + L K+K + L + A+++ + + + D+ S L E +KA+ E T+Q E Sbjct: 770 Q-EELSKTLDKHKQDVSELRKREALLQQQIEFVRHELDESRSQLVEAKKAH-ESTLQALE 827 Query: 823 LVNRLAVLMDHDRVVEKQLLEIEHEN-KELQKKNQILLEENQNLQIS-------LSDMQQ 874 + N M + +KQ+LE++ + K+++ L + + LQ LSD++ Sbjct: 828 INN-----MGDEESGQKQILELKDTHMKQIRAMEAEALSQKKTLQSQIDALNKELSDLEL 882 Query: 875 HYNALVE------KANRTDLAESES--TKYQTQLRDLESNLKRITHEHQTLIVQKKKEIE 926 Y + K L ES++ T+ T+L + E LK + + + +QK +E+E Sbjct: 883 KYKVSIHDYETEVKTLSDQLTESQAIRTQLSTKLSESEEMLKLSSKDMEKKFIQKIRELE 942 Query: 927 DLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNL 986 D + +S IR+ + +E+ LQ+ KN E + E L K + Sbjct: 943 DTNEAIKDRSQSEIRENQAKSEE-------------SLQQLKNMFE---IERETLEKRLI 986 Query: 987 ELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDY 1046 E +K +K Q E+Y ++ + A L +EEI L I + ++ ++M Y Sbjct: 987 EEKEKR-EKSYNQ---VVEEYEQKLREEQAAL---EEEIENLRDDIKDYEIQVINMQGQY 1039 Query: 1047 ESKLAQFTTKLENMEEEMQRVSKQLLDSK-QHNEELQILVREQDDQIKELKETKLTFEMN 1105 E +L +EN+E+ +Q QLL S+ + +L+ + + KEL++ T + N Sbjct: 1040 EHELDLKQKTIENLEKMLQETKAQLLSSQASYQSQLEQQMASYNADRKELQQKYETVQKN 1099 Query: 1106 IPKTEGMIISSTIEPMSDDA---------------NNVDXXXXXXXXXXXXLKVQEEEEF 1150 + ++ I++ T + S +A N ++ K QE + Sbjct: 1100 LQLSDNKILTLTQKLESSEASYENKKKELAQLKQDNIIERQALEEKLEETRKKYQELSDE 1159 Query: 1151 IQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTEN 1210 + + E+S L+++ E Y K +Q L L +E++ K++ Q E Sbjct: 1160 HLQTKINSEKSIALSSQQNEFYQKKVQ--ELQVALESSTQRFEERLKTSKAEWAQETLEK 1217 Query: 1211 -DNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYE 1269 NL L S I++ + + ++ +R D +K + +L ESK + Sbjct: 1218 IQNLQDEKVNLESKINALK-----KSTKEFETQYQKRVTDLEKEKAIYVEKLQYTESKLK 1272 Query: 1270 QLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIED 1329 + D T++ +++ ++ TS + K+ +E + L+ + + N+ L + E Sbjct: 1273 ETEDKYMIETEQLKDQLSKAKEFTSTEKKMLIQE--IEKLKSQNVQLDNEKHELNTSYER 1330 Query: 1330 EKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXX 1389 +KV + DL + + EQ++ ++ ++ K Sbjct: 1331 DKVLWEGKFSFLQQQKEQAKQDLIEAQKKF----EQTLTHLQKQRQNEKNEREQSVSDML 1386 Query: 1390 XXXXRVNDAEAKVLELTHQLELK--DSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKR 1447 R + L+ T +L + +I + E +L Q E + EKR Sbjct: 1387 MQIERKYQTQISELQETSNTKLSAANQKITKLEAELKNSLDQTMMESRQKNSNAIFTEKR 1446 Query: 1448 IEDLTYEKE---SELAILRLKMH-ENANHYETMQKESEIERVKLIEELNVKITESVSLNK 1503 + +L ++ SEL I+R + E + +E E + K++ ++ K E+ K Sbjct: 1447 LAELLESEKKLSSELDIIRKEREAEKTEAQRKLDQERETLKTKML-QIEEKFREA---EK 1502 Query: 1504 QVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASD 1563 + L E+E AK N + L NQ+ E+ ++I + ++ + +++ + Sbjct: 1503 KRNTLIFEHEKERAKWNLEKDHLLNQKNELQENLNKIEKKKEILLRENERLKNDSRQSRR 1562 Query: 1564 TKQGRDEQLDN---TMNKELLDAVPRAELDLAMYMLHQR 1599 + +Q N T N+++++A + L+++ M +R Sbjct: 1563 QFERLSDQNSNIFLTQNRQMMNANQPSFLNMSRNMGSER 1601 >UniRef50_UPI00006615CF Cluster: Homolog of Homo sapiens "Golgi autoantigen, golgin subfamily B member 1; n=1; Takifugu rubripes|Rep: Homolog of Homo sapiens "Golgi autoantigen, golgin subfamily B member 1 - Takifugu rubripes Length = 4286 Score = 136 bits (328), Expect = 6e-30 Identities = 245/1237 (19%), Positives = 519/1237 (41%), Gaps = 111/1237 (8%) Query: 360 SSPSKKGSPL-ISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLN 418 S+P + +P + S +N K++S QL+S Q D + ++ + L +Q L+ Sbjct: 609 STPDTESNPCTLVCFSAQNELEKLQS---QLASVRHQQSRDAEKHQLLVTSLNEQLQGLS 665 Query: 419 KDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHME-GPSLIHVGTNTEDVNE 477 E + EK+ +L L L+ Q E L+ + E++++ Sbjct: 666 DMQESLESSLVEKENTLAKTSEKLELVSSLRESLSLKETQFKEVSDKLLQTEQSLENISQ 725 Query: 478 IAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQIT--QLNDEIDAANKNMIKVKSNHKL 535 E+ EL E+ D+ K + K K+ ++++T L E+D N+ + K+ + + Sbjct: 726 KCSGSEKQCGELKSEVTDLTQKLSLLKEKTQKQEVTIDTLQTEVDQTNEELDKLNTAYLE 785 Query: 536 KLKQMQKTIDNFSKVSDSNKEIV-RLTEELHHLSQKVAELEEEKGNLQLHL-VDYDSGRM 593 + Q+ + + + DS K+++ +E+ LS ++E E+ L+ L + D+ Sbjct: 786 ERAQLIHDLQSCEREIDSLKDVLLEKDKEISVLSGNISEYTEQLIALKQDLKMKEDNLIQ 845 Query: 594 IESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVED----KLADISQ 649 +E+ + K E+ L E++ LE++ +L++ L + + + D K A++ Sbjct: 846 VENALSKAEREVSILRESQNSDQRTLENKITELMENLKDTEMELLKARDLRDSKTAEVET 905 Query: 650 L--QSDQVCSEIKSVH--LEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKE- 704 L Q+D I+ + +++Q+ + E + I +LK EQL + + L+ E Sbjct: 906 LVKQADDDKKAIQELRGEIQKQLQSHCHHLSECEMHIASLK---EQLMSSAQKLQEALEL 962 Query: 705 --DIMNKLQNYIQENMDLTDKLEKMSA--EKISELLAKINHEEQSKIQTQFGIDAKIQER 760 NK Q++ +E D+ ++ + EK + ++ + + + +T+ I +++E+ Sbjct: 963 QQQFSNKEQSFEKELKSSKDEQNRLCSQVEKYRNEMHVVSQQLEEQTRTEDIIRGEMKEK 1022 Query: 761 DLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQE 820 + I ++E +L + +++ EE ED + + + +++ S LQ K + S Sbjct: 1023 EQIIASLEIQLKEAGAQV---EEERQRFEDALKTRDSEREKMSSDLQSKSENISNLQNLL 1079 Query: 821 DELVNRLAVLMDHDRVVEKQLLEIEHEN-KELQKKNQILLEENQNLQISLSDMQQHYNAL 879 + L N L ++ + + E++ +N +L+++ L+ N + Q + + L Sbjct: 1080 NSLKNEKKQLQENLEALTGEF-EMQKQNVHQLKEQVTSALDSNASYQNQVQQLSAEAARL 1138 Query: 880 VEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESA 939 ++ + + + SE + LRD S L+R ++ T+I +K+ E+L ++ N+++ Sbjct: 1139 QQELSDSQITISELRCEKESLRDEVSVLERQVSQNSTVIEALQKDKEELTLQ-NSELSRG 1197 Query: 940 IRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQ 999 + + V QL++ + + NL M +E K ++L Q++++ Sbjct: 1198 ---------RVQSLTSKVDQLQSDVAGKDGTLGNLQMTMEAQQKRLMQL-----QEEESS 1243 Query: 1000 SPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLEN 1059 + E+ K N LK + A N KI S + + +Q +++N Sbjct: 1244 LKSQLREK-EEVWKENQCLKSE-----ASNHKI--TVCSLQAEAESLREQHSQVCQQIKN 1295 Query: 1060 MEEEMQRVSKQLLDSKQHNEELQI---LVREQDDQIKELKETKLTFEMNIPKTEGMII-- 1114 EE ++ V Q ++H EEL + ++ +QI L+ E + G ++ Sbjct: 1296 GEETLRNVKHQ---CQKHKEELNVTNETIKSLTEQIGVLEGNARELESDAELRRGEVVKL 1352 Query: 1115 SSTIEPMSDDANNV-------DXXXXXXXXXXXXLKVQEEEEFIQERS------VLQEQS 1161 S I+ +++ + + + L Q E+ Q S +L E + Sbjct: 1353 QSHIQAATEENHQLRAACESKEKELAHHSQVLLDLNGQLEKALEQNSSFSATVNILTENN 1412 Query: 1162 AKLNTELQECYTKIIQL----ETLNTELTGHD---VVNQEQINQLKSKLEQLNTENDNLL 1214 +L EL + + +L +L L+G + +++ I++L + E+L T D Sbjct: 1413 QRLQEELAQKEKAVSELNADKSSLQELLSGLEKQISEDRQAIDRLLKEKEELATAADGFK 1472 Query: 1215 STVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDS 1274 + E S S+ + Q+ E L K L ++E Q E + +Q+ + Sbjct: 1473 KVLQESEQSNSAGLLQKTNECEALSKV-LKEKEGWLQNLREEA-------DGLKKQVAEL 1524 Query: 1275 VQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADV---INQIEILRSEIEDEK 1331 + TQ+E + Q+ QN+L + +R LQE+ + + I + + L + +E+ Sbjct: 1525 TEMFTQKEQTALAQRSQLEDKQNELLQLHDAIRVLQEQESVLRSGIMEKDALIQQGAEER 1584 Query: 1332 VAFXXXXXXXXXXXXXXXXDLRT------ENQSYKQMQEQSILNINEENAQLKKSSXXXX 1385 + +L T E Q Q +E+ +E + +S Sbjct: 1585 QVYQREISREKSVVSQLQAELETVRGDCAEAQLQLQQREEEFQMSRDELNKQTQSVVLLS 1644 Query: 1386 XXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYE 1445 R + E +V +L + L E+ Q+ E T D+ + +++Q ++ Sbjct: 1645 SQLGEANERAREMEVRVQKLADEHRLLTRELEQRNAE----ATDLTDDAQALKEQSAAFK 1700 Query: 1446 KRIE-DLTYEKESELAILRLKMH-ENANHYETMQKESEIERVKLIEELNVKITESVSLNK 1503 ++ +T S+ + RLK + + +E + E L K T LN Sbjct: 1701 SELQKTVTALARSQEEVTRLKTECSGLERLQGILQEKD-------EALRQKDTLVQQLND 1753 Query: 1504 QVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEI 1540 +AEL+K L+++ + + E + L D++ Sbjct: 1754 SMAELDKMLKQKTDDAVGQSAKISDLEDSVCRLRDQV 1790 Score = 130 bits (315), Expect = 2e-28 Identities = 241/1221 (19%), Positives = 488/1221 (39%), Gaps = 115/1221 (9%) Query: 391 SETLNQDTDKKINKNEI-AKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLI 449 S+ Q+ K K++ A LE ++++L + L +KE V+ K G+D I Sbjct: 280 SQMHEQELFKLAAKSDASADLEQLLKALKQKLHEKEEVLLGKTQVINVLQGEVDGRDQQI 339 Query: 450 AQLQLEHQQHMEGPSLIHVGTNTEDVN----EIAKVQEQLK---QELNDEIKDVNVKDLI 502 EH+ P + TED + + K++ K ++L +E+K + D Sbjct: 340 KVSITEHKCRF--PRVAQAKQKTEDASRSEAKFLKMKAWSKSRIRQLEEELKKIQAGDAH 397 Query: 503 EKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLK------------QMQKTIDNFSKV 550 L S + +IT L +E + +N+ K++ +L+ K + Q+T+ + + Sbjct: 398 LDLISLQSRITALEEERE---ENLCKLEQYDELQAKNEMLQAKLAAYEEQQRTLQ--ADL 452 Query: 551 SDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDV--YKKMIEMENL 608 K L S K + + N + + S +S V +++M+ Sbjct: 453 EQFTKRAASQVRALGFQSTKTSRTHCKCMNGLILASESGSADDAQSQVLEWQEMVAEAAT 512 Query: 609 AETRLKAISLLESQKFD-LVQELHILQQKYDEVEDKLADISQLQSDQV----CSEIKSVH 663 A R K + + + +E L+ + E+E++LA L + +S+ Sbjct: 513 ARERAKEEKAAMALRISHMEEEREALETRQQELEEELAQARGLGQHRAKKPAAPSQRSLQ 572 Query: 664 LEEQIDALSASKKELALVIENLKLDKEQLYG-----TIKDLENDKEDIM-----NKLQNY 713 + + D S + + ++ E + G + D E++ ++ N+L+ Sbjct: 573 EDFEFDGQSQFQDPRSTSESTTPMEGENMGGWWPEHSTPDTESNPCTLVCFSAQNELEK- 631 Query: 714 IQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESEL-- 771 +Q + + AEK L+ +N + Q Q +++ + E++ + +L Sbjct: 632 LQSQLASVRHQQSRDAEKHQLLVTSLNEQLQGLSDMQESLESSLVEKENTLAKTSEKLEL 691 Query: 772 -SKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVL 830 S + + E + D+ E+ + + +K E + +L +L++L Sbjct: 692 VSSLRESLSLKETQFKEVSDKLLQTEQSLENISQKCSGSEKQCGELKSEVTDLTQKLSLL 751 Query: 831 MDHDRVVEKQL----LEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNAL----VEK 882 + + E + E++ N+EL K N LEE L L ++ ++L +EK Sbjct: 752 KEKTQKQEVTIDTLQTEVDQTNEELDKLNTAYLEERAQLIHDLQSCEREIDSLKDVLLEK 811 Query: 883 ANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRD 942 + ++Y QL L+ +LK + ++Q + + E E + ES D Sbjct: 812 DKEISVLSGNISEYTEQLIALKQDLKM----KEDNLIQVENALSKAEREVSILRESQNSD 867 Query: 943 KKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEEL------NKMNLELIDKHVQKQ 996 ++ L K + +E + E +L + ++ ++ VE L +K ++ + +QKQ Sbjct: 868 QRTLENKITELMENLKDTEMELLKARDLRDSKTAEVETLVKQADDDKKAIQELRGEIQKQ 927 Query: 997 QTQSPDYTEQYINEINKLNALLK---QKDEEIIALNQKINNAQVSYMSMVSDYESKLAQF 1053 + + I L L QK +E + L Q+ +N + S+ + + + + Sbjct: 928 LQSHCHHLSECEMHIASLKEQLMSSAQKLQEALELQQQFSNKEQSFEKELKSSKDEQNRL 987 Query: 1054 TTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIK----ELKETKLTFEMNIPKT 1109 +++E EM VS+QL + + + ++ ++E++ I +LKE E + Sbjct: 988 CSQVEKYRNEMHVVSQQLEEQTRTEDIIRGEMKEKEQIIASLEIQLKEAGAQVEEERQRF 1047 Query: 1110 EGMIIS--STIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTE 1167 E + + S E MS D + LK E+ LQE L E Sbjct: 1048 EDALKTRDSEREKMSSDLQSKSENISNLQNLLNSLK--------NEKKQLQENLEALTGE 1099 Query: 1168 LQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSA 1227 + + QL+ T + Q Q+ QL ++ +L E + T++ELR S Sbjct: 1100 FEMQKQNVHQLKEQVTSALDSNASYQNQVQQLSAEAARLQQELSDSQITISELRCEKESL 1159 Query: 1228 VDQRGFEIAELWKQHLAQREADFQKTEHELRVQLS--------AFESKYEQLLDSVQSST 1279 D+ ++ Q+ EA QK + EL +Q S + SK +QL V Sbjct: 1160 RDEVSVLERQV-SQNSTVIEA-LQKDKEELTLQNSELSRGRVQSLTSKVDQLQSDVAGKD 1217 Query: 1280 QEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXX 1339 N +TME +LQ++E L++ + +V + + L+SE + K+ Sbjct: 1218 GTLGNLQMTMEAQQKRLMQLQEEESSLKSQLREKEEVWKENQCLKSEASNHKITVCSLQA 1277 Query: 1340 XXXXXXXXXXXDLRTENQSYKQMQ--EQSILNINEENAQLKKSSXXXXXXXXXXXXRVND 1397 +Q +Q++ E+++ N+ + + K+ ++ Sbjct: 1278 EAESLR-------EQHSQVCQQIKNGEETLRNVKHQCQKHKEELNVTNETIKSLTEQIGV 1330 Query: 1398 AEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEF----ENVRQQLVEYEKRIEDLTY 1453 E EL EL+ E+ K + T+ N + E+ ++L + + + DL Sbjct: 1331 LEGNARELESDAELRRGEVV-KLQSHIQAATEENHQLRAACESKEKELAHHSQVLLDLNG 1389 Query: 1454 EKESEL---AILRLKMHENANHYETMQKESEIERVKLIEELNV---KITESVS-LNKQVA 1506 + E L + ++ + + +Q+E ++ K + ELN + E +S L KQ++ Sbjct: 1390 QLEKALEQNSSFSATVNILTENNQRLQEEL-AQKEKAVSELNADKSSLQELLSGLEKQIS 1448 Query: 1507 ELNKALEEEVAKTNEMQTALE 1527 E +A++ + + E+ TA + Sbjct: 1449 EDRQAIDRLLKEKEELATAAD 1469 Score = 124 bits (298), Expect = 3e-26 Identities = 271/1456 (18%), Positives = 597/1456 (41%), Gaps = 113/1456 (7%) Query: 143 DVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEK-DQIIEAKNKATTXXXXXXX 201 ++ L + + EKD +SVL + ++ L++ + K D +I+ +N A + Sbjct: 800 EIDSLKDVLLEKDKEISVLSGNISEYTEQLIALKQDLKMKEDNLIQVEN-ALSKAEREVS 858 Query: 202 XXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLE 261 + ++T++ EN KD + LLK + +D + + +E K + Sbjct: 859 ILRESQNSDQRTLENKITELMENL-------KDTEMELLKARDLRDSKTAEVETLVKQAD 911 Query: 262 AARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQ--SIEPSCEEKTEIEEK-GSLEI 318 + I ++ ++L+ L +Q S +E E++++ + E Sbjct: 912 DDKKAIQELRGEIQKQLQSHCHHLSECEMHIASLKEQLMSSAQKLQEALELQQQFSNKEQ 971 Query: 319 ANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNT 378 + EL + L Q+ + E+ + + E + + +G + + Sbjct: 972 SFEKELKSSKDEQNRLCSQVEKYRNEMH--VVSQQLEEQTRTEDIIRGEMKEKEQIIASL 1029 Query: 379 ASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVI-SEKDTXXXX 437 ++K +Q+ E + K +E K+ +QS ++++ + + ++ S K+ Sbjct: 1030 EIQLKEAGAQVEEERQRFEDALKTRDSEREKMSSDLQSKSENISNLQNLLNSLKNEKKQL 1089 Query: 438 XXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTED-VNEIAKVQEQLKQELNDEIKDV 496 Q Q HQ + S + + ++ V +++ +L+QEL+D + Sbjct: 1090 QENLEALTGEFEMQKQNVHQLKEQVTSALDSNASYQNQVQQLSAEAARLQQELSD--SQI 1147 Query: 497 NVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKE 556 + +L + +S ++++ L ++ + N +I+ K +L T+ N S++ S Sbjct: 1148 TISELRCEKESLRDEVSVLERQV-SQNSTVIEALQKDKEEL-----TLQN-SEL--SRGR 1198 Query: 557 IVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAI 616 + LT ++ L VA + GNLQ+ ++ R+++ + ++ ++ R K Sbjct: 1199 VQSLTSKVDQLQSDVAGKDGTLGNLQM-TMEAQQKRLMQLQEEESSLK----SQLREKEE 1253 Query: 617 SLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVH--LEEQIDALSAS 674 E+Q H + + E A+ + Q QVC +IK+ L Sbjct: 1254 VWKENQCLKSEASNHKITVCSLQAE---AESLREQHSQVCQQIKNGEETLRNVKHQCQKH 1310 Query: 675 KKELALVIENLKLDKEQ---LYGTIKDLENDKE---DIMNKLQNYIQENMDLTDKLEKMS 728 K+EL + E +K EQ L G ++LE+D E + KLQ++IQ + +L Sbjct: 1311 KEELNVTNETIKSLTEQIGVLEGNARELESDAELRRGEVVKLQSHIQAATEENHQLRAAC 1370 Query: 729 AEKISELLAKINHEEQSKIQTQFGIDAKIQERDLY--IENIESELS-KYKSRICRLEESI 785 K EL H Q + ++ +++ + NI +E + + + + + E+++ Sbjct: 1371 ESKEKELA----HHSQVLLDLNGQLEKALEQNSSFSATVNILTENNQRLQEELAQKEKAV 1426 Query: 786 AVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRL----AVLMDHDRVVEKQL 841 + + + SL+ L + E ++A +++EL VL + ++ L Sbjct: 1427 SELNADKSSLQELLSGLEKQISEDRQAIDRLLKEKEELATAADGFKKVLQESEQSNSAGL 1486 Query: 842 LEIEHENKELQKKNQILLEEN---QNLQISLSDMQQHYNALVEKANRTDLAESESTKYQT 898 L+ +E + L K +L E+ QNL+ +++ L E + E + ++ Sbjct: 1487 LQKTNECEALSK---VLKEKEGWLQNLREEADGLKKQVAELTEMFTQ---KEQTALAQRS 1540 Query: 899 QLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVT 958 QL D ++ L ++ H+ ++ +++ + +E + I+ +++V + + V+ Sbjct: 1541 QLEDKQNELLQL-HDAIRVLQEQESVLRSGIMEKDALIQQGAEERQVYQREISREKSVVS 1599 Query: 959 QLEAQLQEYKNNI-----------ENLNMNVEELNKMNLELIDKHVQ-KQQTQSPDYTEQ 1006 QL+A+L+ + + E M+ +ELNK ++ Q + + E Sbjct: 1600 QLQAELETVRGDCAEAQLQLQQREEEFQMSRDELNKQTQSVVLLSSQLGEANERAREMEV 1659 Query: 1007 YINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQR 1066 + ++ + LL ++ E+ A + + + + ++S+L + T L +EE+ R Sbjct: 1660 RVQKLADEHRLLTRELEQRNAEATDLTDDAQALKEQSAAFKSELQKTVTALARSQEEVTR 1719 Query: 1067 VSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDAN 1126 + + E LQ +++E+D+ +++ K+T L ++N E + ++ +DDA Sbjct: 1720 LKTEC----SGLERLQGILQEKDEALRQ-KDT-LVQQLNDSMAE---LDKMLKQKTDDAV 1770 Query: 1127 NVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQ---EQSAKLNTELQECYTKIIQLETLNT 1183 L+ Q + + E S LQ +Q +L+ E Q +Q TL T Sbjct: 1771 GQSAKISDLEDSVCRLRDQVDSSGL-EVSTLQHSLKQKEELSLEWQSQSAAAVQ--TLGT 1827 Query: 1184 ELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHL 1243 L +V + + LK K+ L + L +T+ S + G + L Q Sbjct: 1828 NLQAKEV----ECSSLKEKVFHLEESVEKLNNTLQAQTSEVEDLKRVLGQKDVALSDQFK 1883 Query: 1244 AQREADFQKTEHEL-RVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDK 1302 ++ + E L + Q + QL + S + + + + E+ S N L + Sbjct: 1884 CLQDVQRRADEALLFKTQFTESAELVSQLQSQLHSLSTDSEHLKKSAEETQSAFNNL--R 1941 Query: 1303 EEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSY-KQ 1361 E++ NL+E D Q+ E+ + LR+E + ++ Sbjct: 1942 EKYAANLEE-LQDARRQLSQRMDEVSGLQ-KLLDDSARQRERASSTTETLRSELSAVCQK 1999 Query: 1362 MQEQSILN--INEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLE----LTHQLELKDSE 1415 ++E LN +++E + S ++ +V LT LE ++ Sbjct: 2000 LEEAEDLNAKLSKEKDEALVSHQANVSLLTVEIEKLKSQYLQVATQLNVLTENLEQREMA 2059 Query: 1416 IYQKTHEYTITLTQRNDEFENVRQQLVEYEKRI-EDLTYEKESELAILRLKMHENANHYE 1474 ++ +Y++ + + + Q+L E +R+ E++ KE +L ENA+ E Sbjct: 2060 LHAINSQYSLQ-NKNTSQLVSEMQKLEEVNQRLKEEIALSKEENRKLLTAVSCENAHLKE 2118 Query: 1475 TMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIV 1534 K S E+ +L + + + ++ + L + +E ++ + +QT + Q+ E+ Sbjct: 2119 EFSK-SLAEKKELENRCH---QMRLQMEEECSSLKEMMERVTSERDGIQTKVSVQDQELC 2174 Query: 1535 TLNDEITNLQNMVRAS 1550 L + + ++ +++ S Sbjct: 2175 QLKENLQKVEQVLQDS 2190 Score = 119 bits (286), Expect = 8e-25 Identities = 296/1591 (18%), Positives = 641/1591 (40%), Gaps = 154/1591 (9%) Query: 89 GISESLANTLKQKEILMEKIKQY-KELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHL 147 G +E A ++++ M+K++Q KE+ SST +L VTH Sbjct: 2540 GAAEKDAAAEQERKDWMQKLEQLQKEIQNASSTA---------SAAVEEAEKELAQVTHE 2590 Query: 148 SNTIKEKDNA--LSVLQVKMKIMETT---ILDLQEKINEKDQIIEAKNKATTXXXXXXXX 202 +++K +A L+ + K E +L E E ++E + + T Sbjct: 2591 KTKLEKKVHAALLARKETTKKAHEREKKLTQELTELKEEYQALLEQQRQQTNDLNALQFN 2650 Query: 203 XXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIES----KDVRISSLEEANK 258 E K ++ E +A + E+ + L+D++ ++++ SL Sbjct: 2651 FEKKVKEVEELNKTSLSDQDE--LASLKQLMQERDKSLQDLKKTMGEREIQSQSLPNLQM 2708 Query: 259 LLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXL--AKQSIEPS---CEEKTEI--E 311 LE + +I + +LA + E L A++ +E + +EKT+ E Sbjct: 2709 ELENLKSQIGKMYEELASKDEALTVGEQGAEALKSKLLTAEKHLEEAQAEIKEKTDQAEE 2768 Query: 312 EKGSLEIANMTELTKKIELLEH---LNCQIRQTNKELENKLATMGT--ESKAVSSPSKKG 366 + +L+ + +K L+ L ++ L++ T E++ + ++ Sbjct: 2769 RRDALKAFELRVQQEKHVLISEKDALESRLNLLESALQHHTETAAALEETRLQCAEKQRS 2828 Query: 367 SPLISRKSGRNTA--SKMKSPWSQLSSETLNQDTDKK--INKNEIAKLEMVIQSLNKDLV 422 ++ R+ TA S++K S + + DK + K + S + Sbjct: 2829 LDVLKREQAEATALISELKDEISSANKKLAEFAKDKTCAVCKTRRDDQDGPCFSCQRH-E 2887 Query: 423 DKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQ 482 + + + E++ K+ LIA L+L+ QQ + H + E A++Q Sbjct: 2888 NLQIKLKEREEAFLMSKAQLSEKEELIAALELQLQQQIGA----HEASMERVKTEAAELQ 2943 Query: 483 E-QLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQ 541 Q +ND+ + L KL++A +L E ++A K +K +++ K + K+++ Sbjct: 2944 RSQHNGTVNDQDNQSKIAALTRKLQAALLSRKELIKE-NSALKQDVKRQAD-KERAKELE 3001 Query: 542 KTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEE-KGNLQLHLVDYDSGRMIESDVYK 600 FS + + +EI R EL + + ++ +G + L D S + + Sbjct: 3002 -----FSSLEAALEEIKRQNMELESSASSASRDKDRLRGEVDQLLSDNHS---LSAACDS 3053 Query: 601 KMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIK 660 + +EN+ + + LES K EL + K+ E++ + + Q + + SE++ Sbjct: 3054 LKLTIENITQQKEAFSCQLESLKDSQTDELSKWKSKHAELKQEYESLLQ-SYENISSEME 3112 Query: 661 SVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDL 720 + + ++A ++E +L+ +++ L + LE ++E I K++ + +E + Sbjct: 3113 K--MRQVLEATKRDQQEAIKKAHHLEAERDVLEKQVAKLEEEQEGIKEKMRKFSKEKLCK 3170 Query: 721 TDKLEKMSAEKISEL--LAKINHEEQSKIQTQFG-IDAKIQERDLYIENIESELSKYKSR 777 ++LE+ + EL L + + E S++ + ++A+I + E ++ +LS+ S Sbjct: 3171 VEELEEENRNTRRELTELTENHRTEVSELTDRNRQLEAEICKLKASSEELDEKLSELHSE 3230 Query: 778 ICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSE-------YTIQEDELVNRLAVL 830 +E A +E+ Y+LE+ + + +Y Q E T Q + + L Sbjct: 3231 N---KEMAAKLEEATYTLEKASTESKTYTSSVQLKLDEALGLSNSLTAQMETQTSELGAQ 3287 Query: 831 MDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDM-QQHYNALVEKANRTDLA 889 M+ + ++K+ + + +++Q +++ L + + L D+ H V + + Sbjct: 3288 MEVNNSLQKEKQSLCQQLEKMQNDHELQLGKKDVVIQELRDVISGHSQETVSLNEKVRIL 3347 Query: 890 ESESTKYQTQLRDLESNLKRITHEHQ---TLIVQKKKEIEDL----------EIEFNTQI 936 E + + Q +L +++ ++ +E++ T+ ++ ++I++L ++E ++Q+ Sbjct: 3348 EDDKSLLQEELENVQEISDKVKNENEYLETVALRNSEKIDELTESIALLQAQKMELSSQL 3407 Query: 937 ESAIRD--KKVLNEKYEKNIEYVTQLEAQLQEYKNNIE---NLNMNVEELNKMNLELIDK 991 +A +D +V EK E+ + V + E +L+ + E N+N ++EL K + I++ Sbjct: 3408 -AATKDMNNQVRQEKEEEQLRLVREFEGKLKTVQRGNEGSKNVNKELQELLKEKHQEINQ 3466 Query: 992 HVQK--------QQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYM--- 1040 Q + +S + Q + E +L LK+ EE+ AL QK A+ Sbjct: 3467 LQQNCIRYQEVILELESSSKSSQAVAE--ELKRELKKSSEELSALQQKCGRAEAELSVQR 3524 Query: 1041 SMVSDYESKLAQFTTKLENMEEEMQRVSK-------------QLLDSKQHNE-----ELQ 1082 ++ + KL ++ + M + + S+ Q DS H E +++ Sbjct: 3525 DLLLQAKEKLLSVESERDQMASHVSQSSRRPDNQVLQETQPVQKTDSHVHKEFVFQQQIE 3584 Query: 1083 ILVREQDDQIKELKETKLTF-----EMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXX 1137 L+ +D + K++ E K EMN K + + +S + Sbjct: 3585 ELILSKDGESKKVDELKRQLDSKDGEMNALKRAMKTNEAKLSALSSSPGGAEASSLWNHL 3644 Query: 1138 XXXXLKVQE----EEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQ 1193 L ++ E+ F+ +R L++ K + E+ + ++LE E + Q Sbjct: 3645 YQKALNEKDNQLLEQGFVIKR-FLEDMRVK-DKEMNDLRVTHLKLERTINEYSVAAAAQQ 3702 Query: 1194 EQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKT 1253 Q+ L + +L+ + + + V +L + + + + +L A K Sbjct: 3703 RQLFVLSADNAELSESAELMAAQVKDLSDHVERLEEDKNVQNRQLSDGEDAVSRMQL-KL 3761 Query: 1254 EHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVT-SLQNKLQDKEEHLRNLQE- 1311 +H ++ A E++ LL S Q ++ ++ E +T L+ LQ K+ + +L Sbjct: 3762 QHTEKINADA-EAQL-LLLRSQNDRLQADSERL---EGITVHLKTLLQSKDAEIASLLSC 3816 Query: 1312 KYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNIN 1371 + + I+ L++ + A+ +LR + +Q Q + Sbjct: 3817 RDGQMSGYIQQLQANHRSQAAAYEDRLASLGHRREAAVKELRRLEAKLRHLQVQVDRSSQ 3876 Query: 1372 E-ENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLE-------LKDSEIYQKTHEY 1423 E E +K S ++ + L T + L + Q+ + Sbjct: 3877 EREQTAVKMESFKESMASLQSERERLISQQRTLATTGGKDGAASGERLVSKGMKQEIRKL 3936 Query: 1424 TITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIE 1483 + N E +R QLV Y + + + K+++L +L K + + E + +E Sbjct: 3937 LNQMDDLNSENAMLRAQLVRYREDLNQVLSLKDNQLKVLLQKQQDVIRNLEHQKAAAEKR 3996 Query: 1484 RVKLIEELNVKITESVSLNKQVAELNK--ALEEEVAKTNEMQTALENQEIEIVTLNDEIT 1541 + E+ + ES +L ++++L A +E T Q + N+ I L D + Sbjct: 3997 HRETRLEIQRRGEESGALAAEISQLKDRVATQEAEILTLRNQRSATNEGRVIADLQDAVA 4056 Query: 1542 NLQNMVRASSSKIQKHVSFASDTKQGRDEQL 1572 + A S +Q+++ G EQ+ Sbjct: 4057 ----VKAAECSHLQQNLLSQRTLTDGLQEQI 4083 Score = 113 bits (271), Expect = 5e-23 Identities = 267/1432 (18%), Positives = 600/1432 (41%), Gaps = 114/1432 (7%) Query: 216 QQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLA 275 Q ++ MQE+ +E+ +++ L K E ++ +SSL E+ L E E+S + + Sbjct: 662 QGLSDMQES---LESSLVEKENTLAKTSEKLEL-VSSLRESLSLKETQFKEVSDKLLQTE 717 Query: 276 QELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIEL-LEHL 334 Q LE KQ E E T++ +K SL + E T+K E+ ++ L Sbjct: 718 QSLENISQKCSGS-------EKQCGELK-SEVTDLTQKLSL----LKEKTQKQEVTIDTL 765 Query: 335 NCQIRQTNKELENKLATMGTESKA-----VSSPSKKGSPLISRKSGRN-TASKMKSPWSQ 388 ++ QTN+EL+ KL T E +A + S ++ L ++ S + S+ Sbjct: 766 QTEVDQTNEELD-KLNTAYLEERAQLIHDLQSCEREIDSLKDVLLEKDKEISVLSGNISE 824 Query: 389 LSSETLNQDTDKKINKNEIAKLEMVIQSLNKDL-VDKEYVISEKDTXXXXXXXXXXG-KD 446 + + + D K+ ++ + ++E + +++ + +E S++ T KD Sbjct: 825 YTEQLIALKQDLKMKEDNLIQVENALSKAEREVSILRESQNSDQRTLENKITELMENLKD 884 Query: 447 T---LIAQLQLEHQQHMEGPSLI-HVGTNTEDVNEI-AKVQEQLKQELND----EIKDVN 497 T L+ L + E +L+ + + + E+ ++Q+QL+ + E+ + Sbjct: 885 TEMELLKARDLRDSKTAEVETLVKQADDDKKAIQELRGEIQKQLQSHCHHLSECEMHIAS 944 Query: 498 VKDLI----EKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDS 553 +K+ + +KL+ A E Q +++ + K + K Q++K + VS Sbjct: 945 LKEQLMSSAQKLQEALELQQQFSNKEQSFEKELKSSKDEQNRLCSQVEKYRNEMHVVSQQ 1004 Query: 554 NKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRL 613 +E R TE++ + ++ E E+ +L++ L ++G +E + + ++ R Sbjct: 1005 LEEQTR-TEDI--IRGEMKEKEQIIASLEIQL--KEAGAQVEEERQRFEDALKTRDSERE 1059 Query: 614 KAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSA 673 K S L+S+ ++ ++L +E + ++ L + + L+EQ+ + Sbjct: 1060 KMSSDLQSKSENISNLQNLLNSLKNEKKQLQENLEALTGEFEMQKQNVHQLKEQVTSALD 1119 Query: 674 SKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKIS 733 S ++ L + +L + +D + +++L+ + D LE+ ++ + Sbjct: 1120 SNASYQNQVQQLSAEAARLQQEL----SDSQITISELRCEKESLRDEVSVLERQVSQNST 1175 Query: 734 ELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRY 793 + A +E+ +Q ++Q ++ ++S+++ + L+ ++ + R Sbjct: 1176 VIEALQKDKEELTLQNSELSRGRVQSLTSKVDQLQSDVAGKDGTLGNLQMTMEAQQKRLM 1235 Query: 794 SLERKADQLGSYLQEKQKAYSEYTIQEDELVNR---LAVLMDHDRVVEKQLLEIEHENKE 850 L+ + L S L+EK++ + E + E N + L + +Q ++ + K Sbjct: 1236 QLQEEESSLKSQLREKEEVWKENQCLKSEASNHKITVCSLQAEAESLREQHSQVCQQIKN 1295 Query: 851 LQKKNQILLEENQNLQISLSDMQQHYNALVE-----KANRTDLAESESTKYQTQLRDLES 905 ++ + + + Q + L+ + +L E + N +L ES++ + ++ L+S Sbjct: 1296 GEETLRNVKHQCQKHKEELNVTNETIKSLTEQIGVLEGNAREL-ESDAELRRGEVVKLQS 1354 Query: 906 NLKRITHEHQTL---IVQKKKEI---EDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQ 959 +++ T E+ L K+KE+ + ++ N Q+E A+ N + + +T+ Sbjct: 1355 HIQAATEENHQLRAACESKEKELAHHSQVLLDLNGQLEKALEQ----NSSFSATVNILTE 1410 Query: 960 LEAQLQEYKNNIENLNMNVEELN--KMNLELIDKHVQKQQTQSPDYTEQYINEINKLNAL 1017 +LQE + V ELN K +L+ + ++KQ ++ ++ + E +L A Sbjct: 1411 NNQRLQE---ELAQKEKAVSELNADKSSLQELLSGLEKQISEDRQAIDRLLKEKEEL-AT 1466 Query: 1018 LKQKDEEIIALNQKINNAQVSYMSMVSDYESK-LAQFTTKLENMEEEMQRVSKQLLDSKQ 1076 ++++ +++ N+A + + + SK L + L+N+ EE + KQ+ + + Sbjct: 1467 AADGFKKVLQESEQSNSAGLLQKTNECEALSKVLKEKEGWLQNLREEADGLKKQVAELTE 1526 Query: 1077 ---HNEELQILVREQ-DDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXX 1132 E+ + R Q +D+ EL +L + + + + ++ S I M DA Sbjct: 1527 MFTQKEQTALAQRSQLEDKQNEL--LQLHDAIRVLQEQESVLRSGI--MEKDA------- 1575 Query: 1133 XXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVN 1192 + + E +E+SV+ + A+L T +C +QL+ E ++ Sbjct: 1576 --LIQQGAEERQVYQREISREKSVVSQLQAELETVRGDCAEAQLQLQQREEEFQ----MS 1629 Query: 1193 QEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQK 1252 ++++N+ + L+++ E+ + D+ EL +Q A+ D Sbjct: 1630 RDELNKQTQSVVLLSSQLGEANERAREMEVRVQKLADEHRLLTREL-EQRNAE-ATDLTD 1687 Query: 1253 TEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLR---NL 1309 L+ Q +AF+S+ ++ + ++ S +E T + LQ LQ+K+E LR L Sbjct: 1688 DAQALKEQSAAFKSELQKTVTALARSQEEVTRLKTECSGLERLQGILQEKDEALRQKDTL 1747 Query: 1310 QEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILN 1369 ++ D + +++ + + D+ V + + +Q S+ Sbjct: 1748 VQQLNDSMAELDKMLKQKTDDAVGQSAKISDLEDSVCRLRDQVDSSGLEVSTLQ-HSLKQ 1806 Query: 1370 INEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQ 1429 E + + + S + +AK +E + L+ K + + + TL Sbjct: 1807 KEELSLEWQSQSAAAVQTLG------TNLQAKEVECS-SLKEKVFHLEESVEKLNNTLQA 1859 Query: 1430 RNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIE 1489 + E E++++ L + + + D ++ ++ + + A ++T ES +L Sbjct: 1860 QTSEVEDLKRVLGQKDVALSD-QFKCLQDVQ----RRADEALLFKTQFTESAELVSQLQS 1914 Query: 1490 ELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRA 1549 +L+ T+S L K E A K L++ ++ DE++ LQ ++ Sbjct: 1915 QLHSLSTDSEHLKKSAEETQSAFNNLREKYAANLEELQDARRQLSQRMDEVSGLQKLLDD 1974 Query: 1550 SSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDLAMYMLHQRDV 1601 S+ + ++ S + E L+A E D A+ + HQ +V Sbjct: 1975 SARQRERASSTTETLRSELSAVCQKLEEAEDLNAKLSKEKDEAL-VSHQANV 2025 Score = 110 bits (265), Expect = 3e-22 Identities = 278/1512 (18%), Positives = 637/1512 (42%), Gaps = 147/1512 (9%) Query: 144 VTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKD-QIIEAKNKAT--TXXXXXX 200 V+ L ++ K+ + K+ E ++ ++ +K + + Q E K++ T T Sbjct: 692 VSSLRESLSLKETQFKEVSDKLLQTEQSLENISQKCSGSEKQCGELKSEVTDLTQKLSLL 751 Query: 201 XXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLL 260 + + ++ + E + + +E+ +L+ D++S + I SL++ LL Sbjct: 752 KEKTQKQEVTIDTLQTEVDQTNEELDKLNTAYLEERAQLIHDLQSCEREIDSLKDV--LL 809 Query: 261 EAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAK-QSIEPSCEEKTEI--EEKGSLE 317 E + EIS+ +++ EQ L + ++ E + I E + S + Sbjct: 810 EKDK-EISVLSGNISEYTEQLIALKQDLKMKEDNLIQVENALSKAEREVSILRESQNSDQ 868 Query: 318 IANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRN 377 ++T+ +E L+ ++ + ++K A + T K K L + Sbjct: 869 RTLENKITELMENLKDTEMELLKARDLRDSKTAEVETLVKQADDDKKAIQELRGEIQKQL 928 Query: 378 TASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXX 437 + ++ +L + K + A LE+ Q NK+ ++ + S KD Sbjct: 929 QSHCHHLSECEMHIASLKEQLMSSAQKLQEA-LELQQQFSNKEQSFEKELKSSKDEQNRL 987 Query: 438 XXXXXXGKDTL-IAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDV 496 ++ + + QLE Q E I G E IA ++ QLK E ++++ Sbjct: 988 CSQVEKYRNEMHVVSQQLEEQTRTED---IIRGEMKEKEQIIASLEIQLK-EAGAQVEEE 1043 Query: 497 NVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKS---NHKLKLKQMQKTIDNFSKVSDS 553 + + LK+ + + +++ ++ + ++N+ +++ + K + KQ+Q+ ++ + + Sbjct: 1044 RQR-FEDALKTRDSEREKMSSDLQSKSENISNLQNLLNSLKNEKKQLQENLEALTGEFEM 1102 Query: 554 NKEIVRLTEELHHLSQKVAELEEEKGNLQ--LHLVDYDSGRMIE--SDVYKKMIEMENLA 609 K+ V H L ++V + + Q + + ++ R+ + SD + E+ Sbjct: 1103 QKQNV------HQLKEQVTSALDSNASYQNQVQQLSAEAARLQQELSDSQITISELRCEK 1156 Query: 610 ETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQID 669 E+ +S+LE Q + LQ+ +E+ + +++S+ + + S++ +Q+ Sbjct: 1157 ESLRDEVSVLERQVSQNSTVIEALQKDKEELTLQNSELSRGRVQSLTSKV------DQLQ 1210 Query: 670 ALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSA 729 + A K + NL++ E + L+ ++ + ++L+ +E + ++ K A Sbjct: 1211 SDVAGKDG---TLGNLQMTMEAQQKRLMQLQEEESSLKSQLRE--KEEVWKENQCLKSEA 1265 Query: 730 EKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVME 789 + + E +S + + +I+ + + N++ + K+K + E+I + Sbjct: 1266 SNHKITVCSLQAEAESLREQHSQVCQQIKNGEETLRNVKHQCQKHKEELNVTNETIKSLT 1325 Query: 790 DRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENK 849 ++ LE A +L S + ++ E+V + + + E + K Sbjct: 1326 EQIGVLEGNARELES----------DAELRRGEVVKLQSHIQAATEENHQLRAACESKEK 1375 Query: 850 ELQKKNQILLEENQNLQISL---SDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESN 906 EL +Q+LL+ N L+ +L S N L E R ++ K ++L +S+ Sbjct: 1376 ELAHHSQVLLDLNGQLEKALEQNSSFSATVNILTENNQRLQEELAQKEKAVSELNADKSS 1435 Query: 907 LKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKN----IEYVTQLEA 962 L+ + + I + ++ I+ L E +A KKVL E + N ++ + EA Sbjct: 1436 LQELLSGLEKQISEDRQAIDRLLKEKEELATAADGFKKVLQESEQSNSAGLLQKTNECEA 1495 Query: 963 Q---LQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYT--EQYINEINKLNAL 1017 L+E + ++NL + L K EL + QK+QT + E NE+ +L+ Sbjct: 1496 LSKVLKEKEGWLQNLREEADGLKKQVAELTEMFTQKEQTALAQRSQLEDKQNELLQLHDA 1555 Query: 1018 LK--QKDEEII--------ALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRV 1067 ++ Q+ E ++ AL Q+ + Y +S +S ++Q +LE + + Sbjct: 1556 IRVLQEQESVLRSGIMEKDALIQQGAEERQVYQREISREKSVVSQLQAELETVRGDCAEA 1615 Query: 1068 SKQLLDSKQH--------NEELQILVREQDDQIKELKETKLTFEMNIPKT--EGMIISST 1117 QL ++ N++ Q +V Q+ E E E+ + K E +++ Sbjct: 1616 QLQLQQREEEFQMSRDELNKQTQSVVL-LSSQLGEANERAREMEVRVQKLADEHRLLTRE 1674 Query: 1118 IEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQ 1177 +E + +A ++ K E ++ + + QE+ +L TE Sbjct: 1675 LEQRNAEATDLTDDAQALKEQSAAFK-SELQKTVTALARSQEEVTRLKTECSGLERLQGI 1733 Query: 1178 LETLNTELTGHDVVNQEQINQLKSKLEQ-LNTENDNLL---STVAELRSSIS---SAVDQ 1230 L+ + L D + Q Q+N ++L++ L + D+ + + +++L S+ VD Sbjct: 1734 LQEKDEALRQKDTLVQ-QLNDSMAELDKMLKQKTDDAVGQSAKISDLEDSVCRLRDQVDS 1792 Query: 1231 RGFEIAELW-----KQHLA-----QREADFQKTEHELR---VQLSAFESKYEQLLDSVQ- 1276 G E++ L K+ L+ Q A Q L+ V+ S+ + K L +SV+ Sbjct: 1793 SGLEVSTLQHSLKQKEELSLEWQSQSAAAVQTLGTNLQAKEVECSSLKEKVFHLEESVEK 1852 Query: 1277 --SSTQEETNKIVTMEQVTSLQN-KLQDKEEHLRNLQEKY-------------ADVINQI 1320 ++ Q +T+++ +++V ++ L D+ + L+++Q + A++++Q+ Sbjct: 1853 LNNTLQAQTSEVEDLKRVLGQKDVALSDQFKCLQDVQRRADEALLFKTQFTESAELVSQL 1912 Query: 1321 EI----LRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQ-----SILNIN 1371 + L ++ E K + +L + +Q+ ++ + + Sbjct: 1913 QSQLHSLSTDSEHLKKSAEETQSAFNNLREKYAANLEELQDARRQLSQRMDEVSGLQKLL 1972 Query: 1372 EENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRN 1431 +++A+ ++ + V + +L +L K+ + +H+ ++L Sbjct: 1973 DDSARQRERASSTTETLRSELSAVCQKLEEAEDLNAKLS-KEKDEALVSHQANVSLL--T 2029 Query: 1432 DEFENVRQQLVEYEKRIEDLTYEKES-ELAILRLKMHENANHYETMQKESEIERVKLIEE 1490 E E ++ Q ++ ++ LT E E+A+ + + + T Q SE+++ +EE Sbjct: 2030 VEIEKLKSQYLQVATQLNVLTENLEQREMALHAINSQYSLQNKNTSQLVSEMQK---LEE 2086 Query: 1491 LNVKITESVSLNKQ--------VAELNKALEEEVAKTNEMQTALENQEIEI-VTLNDEIT 1541 +N ++ E ++L+K+ V+ N L+EE +K+ + LEN+ ++ + + +E + Sbjct: 2087 VNQRLKEEIALSKEENRKLLTAVSCENAHLKEEFSKSLAEKKELENRCHQMRLQMEEECS 2146 Query: 1542 NLQNMVRASSSK 1553 +L+ M+ +S+ Sbjct: 2147 SLKEMMERVTSE 2158 Score = 107 bits (258), Expect = 2e-21 Identities = 274/1457 (18%), Positives = 572/1457 (39%), Gaps = 136/1457 (9%) Query: 144 VTHLSNTIKEKDNALSVLQVKMKIMETTILDLQE-------KINEKDQIIEAKNKATTXX 196 V L + + KD L LQ+ M+ + ++ LQE ++ EK+++ + +N+ Sbjct: 1206 VDQLQSDVAGKDGTLGNLQMTMEAQQKRLMQLQEEESSLKSQLREKEEVWK-ENQCLKSE 1264 Query: 197 XXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDV---RISSL 253 E ++Q +++ + E ++ K + K E +V I SL Sbjct: 1265 ASNHKITVCSLQAEAESLREQHSQVCQQIKNGEETLRNVKHQCQKHKEELNVTNETIKSL 1324 Query: 254 EEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEK-TEIEE 312 E +LE E+ + EL + + +CE K E+ Sbjct: 1325 TEQIGVLEGNARELESD-----AELRRGEVVKLQSHIQAATEENHQLRAACESKEKELAH 1379 Query: 313 KGSLEIANMTELTKKIELLEHLNCQIR---QTNKELENKLATMGTESKAVSSPSKKGSPL 369 + + +L K +E + + + N+ L+ +LA + KAVS + S L Sbjct: 1380 HSQVLLDLNGQLEKALEQNSSFSATVNILTENNQRLQEELA---QKEKAVSELNADKSSL 1436 Query: 370 ISRKSG-RNTASKMKSPWSQLSSE-----TLNQDTDKKINKNEIAKLEMVIQSLNK-DLV 422 SG S+ + +L E T K + ++E + ++Q N+ + + Sbjct: 1437 QELLSGLEKQISEDRQAIDRLLKEKEELATAADGFKKVLQESEQSNSAGLLQKTNECEAL 1496 Query: 423 DKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQ 482 K V+ EK+ G +A+L E E +L + NE+ ++ Sbjct: 1497 SK--VLKEKEGWLQNLREEADGLKKQVAEL-TEMFTQKEQTALAQRSQLEDKQNELLQLH 1553 Query: 483 EQLK--QELNDEI------KDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHK 534 + ++ QE + KD ++ E+ + + +I++ + + V+ + Sbjct: 1554 DAIRVLQEQESVLRSGIMEKDALIQQGAEERQVYQREISREKSVVSQLQAELETVRGDCA 1613 Query: 535 LKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDY-DSGRM 593 Q+Q+ + F S E+ + T+ + LS ++ E E +++ + D R+ Sbjct: 1614 EAQLQLQQREEEFQM---SRDELNKQTQSVVLLSSQLGEANERAREMEVRVQKLADEHRL 1670 Query: 594 IESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSD 653 + ++ ++ E +L + + K +L + + L + +EV + S L+ Sbjct: 1671 LTRELEQRNAEATDLTDDAQALKEQSAAFKSELQKTVTALARSQEEVTRLKTECSGLERL 1730 Query: 654 QVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNY 713 Q + K L ++ + +A + + LK + G + +D ED + +L++ Sbjct: 1731 QGILQEKDEALRQKDTLVQQLNDSMAELDKMLKQKTDDAVGQSAKI-SDLEDSVCRLRDQ 1789 Query: 714 IQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSK 773 + S ++S L + +E+ ++ Q A +Q ++ E E S Sbjct: 1790 VDS-----------SGLEVSTLQHSLKQKEELSLEWQSQSAAAVQTLGTNLQAKEVECSS 1838 Query: 774 YKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYS-EYTIQEDELVNRLAVLMD 832 K ++ LEES+ + + + + + L L +K A S ++ +D V R A D Sbjct: 1839 LKEKVFHLEESVEKLNNTLQAQTSEVEDLKRVLGQKDVALSDQFKCLQD--VQRRA---D 1893 Query: 833 HDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEK--ANRTDLAE 890 + + Q E +LQ + L ++++L+ S + Q +N L EK AN +L + Sbjct: 1894 EALLFKTQFTESAELVSQLQSQLHSLSTDSEHLKKSAEETQSAFNNLREKYAANLEELQD 1953 Query: 891 S---------ESTKYQTQLRDLESNLKRITHEHQTL------IVQKKKEIEDLEIEFNTQ 935 + E + Q L D +R + +TL + QK +E EDL + + + Sbjct: 1954 ARRQLSQRMDEVSGLQKLLDDSARQRERASSTTETLRSELSAVCQKLEEAEDLNAKLSKE 2013 Query: 936 IESAIRDKKVLNEKYEKNIEYVT-QLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQ 994 + A+ ++ N+ +T ++E +Y LN+ E L + + L + Sbjct: 2014 KDEAL-------VSHQANVSLLTVEIEKLKSQYLQVATQLNVLTENLEQREMAL--HAIN 2064 Query: 995 KQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMS-----MVSDYESK 1049 Q + T Q ++E+ KL + Q+ +E IAL+++ N ++ +S + ++ Sbjct: 2065 SQYSLQNKNTSQLVSEMQKLEE-VNQRLKEEIALSKEENRKLLTAVSCENAHLKEEFSKS 2123 Query: 1050 LAQFTTKLEN--------MEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLT 1101 LA+ +LEN MEEE + + + + +Q V QD ++ +LKE Sbjct: 2124 LAE-KKELENRCHQMRLQMEEECSSLKEMMERVTSERDGIQTKVSVQDQELCQLKENLQK 2182 Query: 1102 FEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQS 1161 E + +E + + N+ K + + Q+ LQE+ Sbjct: 2183 VEQVLQDSEREWL--FVLDREKQEKNLLVEQLKSVENEMKSKDIKVDALKQDLDGLQEKL 2240 Query: 1162 AKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELR 1221 A ++ +++ QL E + V++ Q+ ++ + +++ EN L + + Sbjct: 2241 ALASSAIRQGSD---QLSAKELEAS----VSRVQLEKVLASVQEKEFENSRLKEALNAAQ 2293 Query: 1222 SSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQE 1281 + + + +RGF I +R + L+ ++ E+ ++ +D++ S + Sbjct: 2294 HQLHALLQKRGFSICA-----PGERSPALSDEQVSLQNMITRLEASHQGEVDTLNSDLNQ 2348 Query: 1282 ETNKIVTMEQVTSLQNKLQDKEEH-LRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXX 1340 + EQ+ + D+++H LQ K + +Q L +E+E K A Sbjct: 2349 TVAHLKRTEQMLHEGERCSDEKDHQTALLQTKVEQLQSQ---LSAEVERAKDAAVTLSCL 2405 Query: 1341 XXXXXXXXXXDLRTENQSYKQM-----QEQSILNINEENAQLKKSSXXXXXXXXXXXXRV 1395 R Q +Q+ Q +L+ + AQ+ +S+ V Sbjct: 2406 NSELREKGDQIGRMNIQISQQLLLLADLSQQLLDKDASIAQVMESAANERIKTREENSAV 2465 Query: 1396 NDAEAKVLELTHQLELK---DSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLT 1452 + + LE H K + E + E + E + + L E E+R+ T Sbjct: 2466 -VGQLQSLEQEHATSAKRKGNLETEGQITEQKAQSERLQSEKQLLESTLNEKEQRLSQ-T 2523 Query: 1453 YEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKAL 1512 + +E + L ++ A + ++ + ++ +E+L +I + S E Sbjct: 2524 LQTLTEKSFLLEQLQAGAAEKDAAAEQERKDWMQKLEQLQKEIQNASSTASAAVE---EA 2580 Query: 1513 EEEVAKTNEMQTALENQ 1529 E+E+A+ +T LE + Sbjct: 2581 EKELAQVTHEKTKLEKK 2597 Score = 97.5 bits (232), Expect = 3e-18 Identities = 261/1435 (18%), Positives = 593/1435 (41%), Gaps = 124/1435 (8%) Query: 216 QQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLA 275 Q++ +++EN +E +D ++ L ++ + + L E K +E ++ L Sbjct: 2171 QELCQLKENLQKVEQVLQDSEREWLFVLDREKQEKNLLVEQLKSVENEMKSKDIKVDALK 2230 Query: 276 QELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLN 335 Q+L+ LA +I ++ + E + S+ + ++ ++ E N Sbjct: 2231 QDLD--------GLQEKLALASSAIRQGSDQLSAKELEASVSRVQLEKVLASVQEKEFEN 2282 Query: 336 CQIRQTNKELENKL-ATMGTESKAVSSPSKKGSPLISRK--SGRNTASKMKSPWSQLSSE 392 ++++ +++L A + ++ +P ++ SP +S + S +N +++++ Q + Sbjct: 2283 SRLKEALNAAQHQLHALLQKRGFSICAPGER-SPALSDEQVSLQNMITRLEAS-HQGEVD 2340 Query: 393 TLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTX-----XXXXXXXXXGKDT 447 TLN D ++ + + + E ++ + +K++ + T KD Sbjct: 2341 TLNSDLNQTVA--HLKRTEQMLHEGERCSDEKDHQTALLQTKVEQLQSQLSAEVERAKDA 2398 Query: 448 LIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKS 507 + L + +G +G +++ + L Q+L D KD ++ ++E + Sbjct: 2399 AVTLSCLNSELREKGDQ---IGRMNIQISQQLLLLADLSQQLLD--KDASIAQVMES--A 2451 Query: 508 AEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHL 567 A E+I + +E A + ++ H K+ + ++ ++++ + RL E L Sbjct: 2452 ANERI-KTREENSAVVGQLQSLEQEHATSAKR-KGNLETEGQITEQKAQSERLQSEKQLL 2509 Query: 568 SQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKA-ISLLESQKFDL 626 + L E++ L L + + E + AE K + LE + ++ Sbjct: 2510 E---STLNEKEQRLSQTLQTLTEKSFLLEQLQAGAAEKDAAAEQERKDWMQKLEQLQKEI 2566 Query: 627 VQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLK 686 +E E +LA ++ + ++ ++ + L + A ++E L E + Sbjct: 2567 QNASSTASAAVEEAEKELAQVTH-EKTKLEKKVHAALLARKETTKKAHEREKKLTQELTE 2625 Query: 687 LDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSK 746 L +E Y + + + + + +N LQ ++ + ++L K S EL A + Q + Sbjct: 2626 LKEE--YQALLEQQRQQTNDLNALQFNFEKKVKEVEELNKTSLSDQDEL-ASLKQLMQER 2682 Query: 747 IQTQFGIDAKIQERDLY---IENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLG 803 ++ + + ER++ + N++ EL KS+I ++ E +A ++ E+ A+ L Sbjct: 2683 DKSLQDLKKTMGEREIQSQSLPNLQMELENLKSQIGKMYEELASKDEALTVGEQGAEALK 2742 Query: 804 SYLQEKQK----AYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILL 859 S L +K A +E + D+ R L + V+++ + E L+ + +L Sbjct: 2743 SKLLTAEKHLEEAQAEIKEKTDQAEERRDALKAFELRVQQEKHVLISEKDALESRLNLLE 2802 Query: 860 EENQNLQISLSDMQQHYNALVEKANRTDLA---ESESTKYQTQLRD-LESNLKRITH--E 913 Q+ + + +++ EK D+ ++E+T ++L+D + S K++ + Sbjct: 2803 SALQHHTETAAALEETRLQCAEKQRSLDVLKREQAEATALISELKDEISSANKKLAEFAK 2862 Query: 914 HQTLIVQKKKEI------------EDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLE 961 +T V K + E+L+I+ + E+ + K L+EK E QL+ Sbjct: 2863 DKTCAVCKTRRDDQDGPCFSCQRHENLQIKLKEREEAFLMSKAQLSEKEELIAALELQLQ 2922 Query: 962 AQLQEYKNNIENLNMNVEELNKM--NLELIDKHVQKQ---QTQSPDYTEQYINEINKLNA 1016 Q+ ++ ++E + EL + N + D+ Q + T+ E+ K N+ Sbjct: 2923 QQIGAHEASMERVKTEAAELQRSQHNGTVNDQDNQSKIAALTRKLQAALLSRKELIKENS 2982 Query: 1017 LLKQKDEEIIALNQKINNAQVSYM-SMVSDYESKLAQFTTKLENMEEEMQRVSKQL--LD 1073 LKQ D + A ++ + S + + + + + + + + + + R+ ++ L Sbjct: 2983 ALKQ-DVKRQADKERAKELEFSSLEAALEEIKRQNMELESSASSASRDKDRLRGEVDQLL 3041 Query: 1074 SKQHN-----EELQILVR---EQDD----QIKELKETKLTFEMNIPKTEGMIISSTIEPM 1121 S H+ + L++ + +Q + Q++ LK+++ T E++ K++ + E + Sbjct: 3042 SDNHSLSAACDSLKLTIENITQQKEAFSCQLESLKDSQ-TDELSKWKSKHAELKQEYESL 3100 Query: 1122 SDDANNVDXXXXXXXXXXXXLKVQEEEEFIQ------ERSVLQEQSAKLNTE---LQE-- 1170 N+ K ++E + ER VL++Q AKL E ++E Sbjct: 3101 LQSYENISSEMEKMRQVLEATKRDQQEAIKKAHHLEAERDVLEKQVAKLEEEQEGIKEKM 3160 Query: 1171 ---CYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSA 1227 K+ ++E L E E ++++ +L N L + + +L++S S Sbjct: 3161 RKFSKEKLCKVEELEEENRNTRRELTELTENHRTEVSELTDRNRQLEAEICKLKAS-SEE 3219 Query: 1228 VDQRGFEIAELWKQHLAQ-READF--QKTEHELRVQLSAFESKYEQLL---DSVQSSTQE 1281 +D++ E+ K+ A+ EA + +K E + S+ + K ++ L +S+ + + Sbjct: 3220 LDEKLSELHSENKEMAAKLEEATYTLEKASTESKTYTSSVQLKLDEALGLSNSLTAQMET 3279 Query: 1282 ETNKI-VTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXX 1340 +T+++ ME SLQ + Q + L +Q + + + +++ E+ D Sbjct: 3280 QTSELGAQMEVNNSLQKEKQSLCQQLEKMQNDHELQLGKKDVVIQELRDVISGHSQETVS 3339 Query: 1341 XXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEA 1400 D + + +QE S + EN L+ + + +A Sbjct: 3340 LNEKVRILEDDKSLLQEELENVQEISD-KVKNENEYLETVALRNSEKIDELTESIALLQA 3398 Query: 1401 KVLELTHQL-ELKD--SEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKES 1457 + +EL+ QL KD +++ Q+ E + L + EFE + + +R + + Sbjct: 3399 QKMELSSQLAATKDMNNQVRQEKEEEQLRLVR---EFEGKLKTV----QRGNEGSKNVNK 3451 Query: 1458 ELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVA 1517 EL L + H+ N + ++ I ++I EL + S S EL + L++ Sbjct: 3452 ELQELLKEKHQEINQLQ----QNCIRYQEVILELE---SSSKSSQAVAEELKRELKKSSE 3504 Query: 1518 KTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQL 1572 + + +Q E E+ D + + + + S+ + S S + + D Q+ Sbjct: 3505 ELSALQQKCGRAEAELSVQRDLLLQAKEKLLSVESERDQMASHVSQSSRRPDNQV 3559 Score = 94.3 bits (224), Expect = 2e-17 Identities = 276/1468 (18%), Positives = 592/1468 (40%), Gaps = 137/1468 (9%) Query: 147 LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXX 206 L++ ++EK + + + +++ + DL +++ +KD I ++ Sbjct: 2405 LNSELREKGDQIGRMNIQISQQLLLLADLSQQLLDKDASIAQVMESAANERIKTREENSA 2464 Query: 207 XXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKD-IES-KDVRISSLEEANKLLEAAR 264 + +Q+ + +E E + +Q+ + ++S K + S+L E + L + Sbjct: 2465 VVGQLQSLEQEHATSAKRKGNLETEGQITEQKAQSERLQSEKQLLESTLNEKEQRL-SQT 2523 Query: 265 FEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEE-------KTEIEEKGSLE 317 + E S L ++L+ Q +E +E + E+ E Sbjct: 2524 LQTLTEKSFLLEQLQAGAAEKDAAAEQERKDWMQKLEQLQKEIQNASSTASAAVEEAEKE 2583 Query: 318 IANMTELTKKIELLEHLNCQIR-QTNK---ELENKLATMGTESKAVSSPSKKGSPLISRK 373 +A +T K+E H R +T K E E KL TE K + + L ++ Sbjct: 2584 LAQVTHEKTKLEKKVHAALLARKETTKKAHEREKKLTQELTELK-----EEYQALLEQQR 2638 Query: 374 SGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDT 433 N + ++ + + E + +++E+A L+ ++Q +K L D + + E++ Sbjct: 2639 QQTNDLNALQFNFEKKVKEVEELNKTSLSDQDELASLKQLMQERDKSLQDLKKTMGEREI 2698 Query: 434 XXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVG-TNTEDVNEIAKVQEQLKQELNDE 492 + L +Q+ +++ + VG E + E+ +E E Sbjct: 2699 QSQSLPNLQMELENLKSQIGKMYEELASKDEALTVGEQGAEALKSKLLTAEKHLEEAQAE 2758 Query: 493 IKDV--NVKDLIEKLKSAEEQITQ----LNDEIDA--ANKNMIKVKSNH----------- 533 IK+ ++ + LK+ E ++ Q L E DA + N+++ H Sbjct: 2759 IKEKTDQAEERRDALKAFELRVQQEKHVLISEKDALESRLNLLESALQHHTETAAALEET 2818 Query: 534 KLKLKQMQKTIDNFSK-VSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHL-VDYDSG 591 +L+ + Q+++D + +++ I L +E+ ++K+AE ++K D G Sbjct: 2819 RLQCAEKQRSLDVLKREQAEATALISELKDEISSANKKLAEFAKDKTCAVCKTRRDDQDG 2878 Query: 592 RMIESDVYKKM-IEMENLAETRLKAISLLESQKFDLVQELHI-LQQK-------YDEVED 642 ++ + I+++ E L + + L S+K +L+ L + LQQ+ + V+ Sbjct: 2879 PCFSCQRHENLQIKLKEREEAFLMSKAQL-SEKEELIAALELQLQQQIGAHEASMERVKT 2937 Query: 643 KLADISQLQSDQVC----SEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKD 698 + A++ + Q + ++ K L ++ A S+KEL LK D ++ + Sbjct: 2938 EAAELQRSQHNGTVNDQDNQSKIAALTRKLQAALLSRKELIKENSALKQDVKRQADKERA 2997 Query: 699 LENDKEDIMNKLQNYIQENMDLTDKLEKMSAEK------ISELLAKINHEEQSKIQT-QF 751 E + + L+ ++NM+L S +K + +LL+ NH + + + Sbjct: 2998 KELEFSSLEAALEEIKRQNMELESSASSASRDKDRLRGEVDQLLSD-NHSLSAACDSLKL 3056 Query: 752 GIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQK 811 I+ Q+++ + +ES + + + A ++ SL + + + S +++ ++ Sbjct: 3057 TIENITQQKEAFSCQLESLKDSQTDELSKWKSKHAELKQEYESLLQSYENISSEMEKMRQ 3116 Query: 812 AYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHE-----------NKELQKKNQILLE 860 + E + + L V+EKQ+ ++E E +KE K + L E Sbjct: 3117 VLEATKRDQQEAIKKAHHLEAERDVLEKQVAKLEEEQEGIKEKMRKFSKEKLCKVEELEE 3176 Query: 861 ENQNLQISLSDM-QQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIV 919 EN+N + L+++ + H + E +R E+E K + +L+ L + E++ + Sbjct: 3177 ENRNTRRELTELTENHRTEVSELTDRNRQLEAEICKLKASSEELDEKLSELHSENKEMAA 3236 Query: 920 QKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVE 979 + ++ LE ES V K ++ + L AQ++ + + M V Sbjct: 3237 KLEEATYTLE---KASTESKTYTSSV-QLKLDEALGLSNSLTAQMETQTSEL-GAQMEVN 3291 Query: 980 ELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSY 1039 + + + + ++K Q + I +L ++ +E ++LN+K+ Sbjct: 3292 NSLQKEKQSLCQQLEKMQNDHELQLGKKDVVIQELRDVISGHSQETVSLNEKVR------ 3345 Query: 1040 MSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETK 1099 ++ D +S L + +LEN++E +V K NE L+ + ++I EL E+ Sbjct: 3346 --ILEDDKSLLQE---ELENVQEISDKV-------KNENEYLETVALRNSEKIDELTES- 3392 Query: 1100 LTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQE 1159 + + + + M +SS + D N V V+E E ++ E Sbjct: 3393 ----IALLQAQKMELSSQLAATKDMNNQVRQEKEEEQLRL----VREFEGKLKTVQRGNE 3444 Query: 1160 QSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAE 1219 S +N ELQE + + + +N +L + + QE I +L+S + + L + + Sbjct: 3445 GSKNVNKELQELLKE--KHQEIN-QLQQNCIRYQEVILELESSSKSSQAVAEELKRELKK 3501 Query: 1220 LRSSISSAVDQRGFEIAELWKQH--LAQREADFQKTEHELRVQLSAFESKYEQLLDS-VQ 1276 +S+ + G AEL Q L Q + E E R Q+++ S+ + D+ V Sbjct: 3502 SSEELSALQQKCGRAEAELSVQRDLLLQAKEKLLSVESE-RDQMASHVSQSSRRPDNQVL 3560 Query: 1277 SSTQ--EETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAF 1334 TQ ++T+ V E V Q ++++ +K ++ Q++ E+ K A Sbjct: 3561 QETQPVQKTDSHVHKEFV--FQQQIEELILSKDGESKKVDELKRQLDSKDGEMNALKRAM 3618 Query: 1335 XXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXR 1394 + + + +++ +NE++ QL + R Sbjct: 3619 KTNEAKLSALSSSPGG--AEASSLWNHLYQKA---LNEKDNQLLEQG--FVIKRFLEDMR 3671 Query: 1395 VNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYE 1454 V D E L +TH L+L+ + +EY++ + + + E + E + + Sbjct: 3672 VKDKEMNDLRVTH-LKLE-----RTINEYSVAAAAQQRQLFVLSADNAELSESAELMAAQ 3725 Query: 1455 -KESELAILRLKMHENANHYETMQKESEIERVKL----IEELNVKI-TESVSLNKQVAEL 1508 K+ + RL+ +N + + E + R++L E++N + + L Q L Sbjct: 3726 VKDLSDHVERLEEDKNVQNRQLSDGEDAVSRMQLKLQHTEKINADAEAQLLLLRSQNDRL 3785 Query: 1509 NKALEEEVAKTNEMQTALENQEIEIVTL 1536 E T ++T L++++ EI +L Sbjct: 3786 QADSERLEGITVHLKTLLQSKDAEIASL 3813 Score = 83.0 bits (196), Expect = 6e-14 Identities = 196/1141 (17%), Positives = 485/1141 (42%), Gaps = 88/1141 (7%) Query: 213 DTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHS 272 + KQ+ + +++ + +E EK R + + +D + ++++A+ L EA R + + + Sbjct: 3092 ELKQEYESLLQSYENISSEM--EKMRQVLEATKRDQQ-EAIKKAHHL-EAERDVLEKQVA 3147 Query: 273 KLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLE 332 KL +E E ++ E + + E+ E ++ELT + LE Sbjct: 3148 KLEEEQEGIKEKMRKFSKEKLCKVEELEEENRNTRRELTELTENHRTEVSELTDRNRQLE 3207 Query: 333 HLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRN---TAS-KMK----- 383 C+++ +++EL+ KL+ + +E+K +++ ++ + + + S + T+S ++K Sbjct: 3208 AEICKLKASSEELDEKLSELHSENKEMAAKLEEATYTLEKASTESKTYTSSVQLKLDEAL 3267 Query: 384 ----SPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXX 439 S +Q+ ++T ++N + + + + Q L K D E + +KD Sbjct: 3268 GLSNSLTAQMETQTSELGAQMEVNNSLQKEKQSLCQQLEKMQNDHELQLGKKDVVIQELR 3327 Query: 440 XXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVK 499 G L + + + SL+ E++ + ++ +++K E N+ ++ V ++ Sbjct: 3328 DVISGHSQETVSLNEKVRILEDDKSLLQ-----EELENVQEISDKVKNE-NEYLETVALR 3381 Query: 500 DLIEKLKSAEEQITQLNDEIDAANKNMIKVKS-NHKLKLKQMQKTIDNFSKVSDSNKEIV 558 + EK+ E I L + + + K N++++ ++ ++ + + K + Sbjct: 3382 N-SEKIDELTESIALLQAQKMELSSQLAATKDMNNQVRQEKEEEQLRLVREFEGKLKTVQ 3440 Query: 559 RLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISL 618 R E ++++++ EL +EK + +++ + + R E ++E+E+ +++ Sbjct: 3441 RGNEGSKNVNKELQELLKEK-HQEINQLQQNCIRYQE-----VILELESSSKSSQAVAEE 3494 Query: 619 LESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKEL 678 L+ + +EL LQQK E A++S + + ++ K + +E + D +++ + Sbjct: 3495 LKRELKKSSEELSALQQKCGRAE---AELSVQRDLLLQAKEKLLSVESERDQMASHVSQS 3551 Query: 679 ALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYI---QENMDLTDKLEKMSAEKISEL 735 + +N L + Q + + +++ I D+L++ K E+ Sbjct: 3552 SRRPDNQVLQETQPVQKTDSHVHKEFVFQQQIEELILSKDGESKKVDELKRQLDSKDGEM 3611 Query: 736 --LAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAV---MED 790 L + ++K+ + L+ + L++ +++ LE+ + +ED Sbjct: 3612 NALKRAMKTNEAKLSALSSSPGGAEASSLWNHLYQKALNEKDNQL--LEQGFVIKRFLED 3669 Query: 791 RRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKE 850 R + D ++L + ++ +EY++ +L VL + + + + + K+ Sbjct: 3670 MRVKDKEMNDLRVTHL-KLERTINEYSVAAAAQQRQLFVLSADNAELSESAELMAAQVKD 3728 Query: 851 LQKKNQILLEENQNLQ-ISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKR 909 L + LEE++N+Q LSD + + + K T+ +++ LR L+ Sbjct: 3729 LSDHVE-RLEEDKNVQNRQLSDGEDAVSRMQLKLQHTEKINADAEAQLLLLRSQNDRLQA 3787 Query: 910 ITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKN 969 + + + V K ++ + E + + + RD ++ + + +Q A + Sbjct: 3788 DSERLEGITVHLKTLLQSKDAEIASLL--SCRDGQMSGYIQQLQANHRSQAAAYEDRLAS 3845 Query: 970 NIENLNMNVEELNKMNLELIDKHVQ-KQQTQSPDYTEQYINEINKLNALLKQKDEEIIAL 1028 V+EL ++ +L VQ + +Q + T + + A L+ + E +I+ Sbjct: 3846 LGHRREAAVKELRRLEAKLRHLQVQVDRSSQEREQTAVKMESFKESMASLQSERERLISQ 3905 Query: 1029 NQKI-----NNAQVSYMSMVS-DYESKLAQFTTKLENMEEEMQRVSKQLLDSKQ------ 1076 + + + S +VS + ++ + +++++ E + QL+ ++ Sbjct: 3906 QRTLATTGGKDGAASGERLVSKGMKQEIRKLLNQMDDLNSENAMLRAQLVRYREDLNQVL 3965 Query: 1077 --HNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXX 1134 + +L++L+++Q D I+ L+ K E +T I E + A Sbjct: 3966 SLKDNQLKVLLQKQQDVIRNLEHQKAAAEKRHRETRLEIQRRGEESGALAAEISQLKDRV 4025 Query: 1135 XXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQE 1194 L ++ + E V+ + + + EC +Q + L ++ T D + QE Sbjct: 4026 ATQEAEILTLRNQRSATNEGRVIADLQDAVAVKAAEC--SHLQ-QNLLSQRTLTDGL-QE 4081 Query: 1195 QINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQH--LAQREADFQK 1252 QI L+ + +Q++ AE + S +D G E+ + ++ QR A+ K Sbjct: 4082 QIQLLEKEKKQMS----------AEAKDKGKSQIDAFGREVEGMRRERETAEQRAAELAK 4131 Query: 1253 TEHELRVQLSAFESK------YEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHL 1306 + +L+ +LS +++ + L ++ Q++ ++++ E +L+N+ ++ Sbjct: 4132 DQLQLQQKLSESDTRSRNTRLQNESLCKAMAALQDDRDQLI--EDFKTLRNRYDEELRET 4189 Query: 1307 R 1307 R Sbjct: 4190 R 4190 Score = 45.6 bits (103), Expect = 0.011 Identities = 63/350 (18%), Positives = 144/350 (41%), Gaps = 37/350 (10%) Query: 506 KSAEEQITQLNDEIDAANKNMIKVKSN---HKLKLKQMQKTIDNFSKVS-DSNKEIVRLT 561 K +++I +L +++D N +++ ++ L Q+ DN KV ++++R Sbjct: 3927 KGMKQEIRKLLNQMDDLNSENAMLRAQLVRYREDLNQVLSLKDNQLKVLLQKQQDVIR-- 3984 Query: 562 EELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLES 621 L H + AE + L++ +SG + ++ ++++ T+ I L + Sbjct: 3985 -NLEH-QKAAAEKRHRETRLEIQRRGEESGALAA-----EISQLKDRVATQEAEILTLRN 4037 Query: 622 QKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALV 681 Q+ E ++ D V K A+ S LQ + + + L+EQI L KK+++ Sbjct: 4038 QR-SATNEGRVIADLQDAVAVKAAECSHLQQNLLSQRTLTDGLQEQIQLLEKEKKQMSAE 4096 Query: 682 IENLKLDKEQLYGT-IKDLENDKEDIMNKLQNYIQENMDLTDKLE---------KMSAEK 731 ++ + +G ++ + ++E + ++ + L KL ++ E Sbjct: 4097 AKDKGKSQIDAFGREVEGMRRERETAEQRAAELAKDQLQLQQKLSESDTRSRNTRLQNES 4156 Query: 732 ISELLAKINHEEQSKIQT----QFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAV 787 + + +A + + I+ + D +++E + +E L S + L + V Sbjct: 4157 LCKAMAALQDDRDQLIEDFKTLRNRYDEELRETRAALNKVERSLQDASSDLAMLAKQRDV 4216 Query: 788 M---------EDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLA 828 + +D L + DQL L EK++ ++ ++ +LA Sbjct: 4217 LLLKINALESKDSHAELNKLLDQLSKALSEKERDLTQAVLENSAHSRQLA 4266 Score = 41.1 bits (92), Expect = 0.25 Identities = 90/478 (18%), Positives = 199/478 (41%), Gaps = 54/478 (11%) Query: 319 ANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNT 378 A + EL + L HL Q+ ++++E E M + ++++S + LIS++ T Sbjct: 3852 AAVKELRRLEAKLRHLQVQVDRSSQEREQTAVKMESFKESMASLQSERERLISQQRTLAT 3911 Query: 379 ASKMKSPWS--QLSSETLNQDTDKKINKNEIAKLE--MVIQSLNKDLVDKEYVISEKDTX 434 S +L S+ + Q+ K +N+ + E M+ L + D V+S KD Sbjct: 3912 TGGKDGAASGERLVSKGMKQEIRKLLNQMDDLNSENAMLRAQLVRYREDLNQVLSLKDNQ 3971 Query: 435 XXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIK 494 ++ Q Q + +++E H E + +++ Q + E + + Sbjct: 3972 LK-----------VLLQKQQDVIRNLE-----HQKAAAEKRHRETRLEIQRRGEESGALA 4015 Query: 495 DVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSN 554 + L +++ + E +I L ++ A N+ + + +K ++ S Sbjct: 4016 -AEISQLKDRVATQEAEILTLRNQRSATNEGRVIADLQDAVAVKA--------AECSHLQ 4066 Query: 555 KEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLK 614 + ++ L +++ LE+EK + D ++ D + + E+E + R Sbjct: 4067 QNLLSQRTLTDGLQEQIQLLEKEKKQMSAEAKDKGKSQI---DAFGR--EVEGMRRERET 4121 Query: 615 AISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSAS 674 A E + +L ++ LQQK E + + + ++LQ++ +C A++A Sbjct: 4122 A----EQRAAELAKDQLQLQQKLSESDTRSRN-TRLQNESLCK------------AMAAL 4164 Query: 675 KKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISE 734 + + +IE+ K + + +++ + LQ+ ++ + K + KI+ Sbjct: 4165 QDDRDQLIEDFKTLRNRYDEELRETRAALNKVERSLQD-ASSDLAMLAKQRDVLLLKINA 4223 Query: 735 LLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRR 792 L +K +H E +K+ Q +ERDL +E+ S + ++ S+ ++D R Sbjct: 4224 LESKDSHAELNKLLDQLSKALSEKERDLTQAVLEN--SAHSRQLAAFSRSMGSLQDER 4279 Score = 37.5 bits (83), Expect = 3.0 Identities = 70/396 (17%), Positives = 163/396 (41%), Gaps = 22/396 (5%) Query: 948 EKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQY 1007 E+ + + + +L AQL+E + + + ++ K E + + K + Q+ Sbjct: 31 EEMAERLTHTERLVAQLKEMIREKDAVLCSKDDQLKAEKEASEAKLSKLRLQNKAKVTSL 90 Query: 1008 INEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRV 1067 ++ +L D + A + + + K+ + +L EE+ Sbjct: 91 TIQLEELRRQQGGPDTPTRSKKGSSEGADQASRGKIVLLKKKVEELEQQLAQRVEELDNK 150 Query: 1068 SKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANN 1127 K++ + EE+ ++ E+D ++ E K + +++ S T P + Sbjct: 151 RKEVESQRLRGEEMDAMLIERDRKLTE----KEAYIVHLQTALSGDQSFTPAPAQTSEAS 206 Query: 1128 VDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTEL---QECYTKIIQLETLNTE 1184 KV E EE S+LQEQS L L +E YT+ + N + Sbjct: 207 GAVQELQLLVQSLTRKVGESEE---RYSLLQEQSESLKELLVTEKEQYTRKEIMYKENIQ 263 Query: 1185 LTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSIS---SAVDQRGFEIAELW-- 1239 T D++ Q+ NQL ++ Q++ + L+ ++ + + A+ Q+ E E+ Sbjct: 264 -TFKDIIIQKD-NQL-MEVSQMHEQELFKLAAKSDASADLEQLLKALKQKLHEKEEVLLG 320 Query: 1240 -KQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNK 1298 Q + + + + +++V ++ + ++ ++ + Q + ++ ++ +++ Sbjct: 321 KTQVINVLQGEVDGRDQQIKVSITEHKCRFPRVAQAKQKTEDASRSEAKFLKMKAWSKSR 380 Query: 1299 LQDKEEHLRNLQ--EKYADVIN-QIEILRSEIEDEK 1331 ++ EE L+ +Q + + D+I+ Q I E E E+ Sbjct: 381 IRQLEEELKKIQAGDAHLDLISLQSRITALEEEREE 416 >UniRef50_Q4T928 Cluster: Chromosome undetermined SCAF7646, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome undetermined SCAF7646, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 4089 Score = 135 bits (327), Expect = 8e-30 Identities = 269/1412 (19%), Positives = 567/1412 (40%), Gaps = 115/1412 (8%) Query: 218 MTKMQENFIAMEAEWKDE---KQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKL 274 +T +++ +A + ++ +Q+L K ES + + + +E L + E E + Sbjct: 930 ITSLKDQLVAAAQKLQESSQLQQQLSKKEESLEKELKASKEERNRLHSQAEEYRKEAQTV 989 Query: 275 AQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHL 334 +Q+LE+ A+ + + + +E+ LE T ++K +L L Sbjct: 990 SQQLEEQKRSQGITRGEMKATAETAAALEAQLREAEKERQRLEAELKTRDSEKEKLSSDL 1049 Query: 335 NCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETL 394 + + L+N L ++ +E + + + + + + + ++ S L S T Sbjct: 1050 QSKAENISN-LQNLLNSLKSEKQQLQEELEALTEELDLQKEKVRQLSQEAA-SALDSRTS 1107 Query: 395 NQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQL 454 Q+ ++++ E A+L+ + L + L + + +I L+ Sbjct: 1108 YQNQAQQLSA-EAARLQQELDHLQRTLSELGCEAESRRDRVSVLEAQVSENAAVIKALRE 1166 Query: 455 EHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQ 514 E ++ +L ++E V +A EQL++ L + +D + DL + + ++++TQ Sbjct: 1167 EKEEL----TLQKQELSSEHVQGLASTAEQLRRSLAE--RDEALADLQARADAQQKELTQ 1220 Query: 515 LNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSK-VSDSNKEIVRLTEELHHLSQKVAE 573 L ++ + + K + K + + + ++ + + VS + L E+ + Q++ Sbjct: 1221 LQEQ-ERSLKTQLAEKEHLGRENQSLKSEVGRQEEAVSKLQSDAKSLQEKHSQVCQQMEN 1279 Query: 574 LEEEKGNLQLHLVDYDSGRMIESDVYKKMIE-----------MENLAETRLKAISLLESQ 622 EE N++ + + ++ K + E +E+ AE R K + L SQ Sbjct: 1280 REETLRNVKRECQQHKEELNVRNETIKSLTEQMGLLRGAAGELESGAELRQKELIQLHSQ 1339 Query: 623 KFDLVQELHILQQKYDEVEDKLADISQLQSDQVCS-EIKSVHLEEQIDALSASKKELALV 681 L ++ LQ E +LA LQS ++C + + EQ +LSA L Sbjct: 1340 IQALTEDKQQLQAARRTTEKELA----LQSQRLCDLQGQLKEALEQNSSLSAELGSLTQK 1395 Query: 682 IENLKLDKEQLYGTIKDLENDKEDIMNKL---QNYIQENMDLTDKLEKMSAE---KISEL 735 L+ D Q ++ +L D+ + +L + I E+ TD+L K E + EL Sbjct: 1396 NRALREDLAQKLESVSELAADRSALQQQLSGLEEQIAEDRQATDRLVKQKEELGSTVDEL 1455 Query: 736 LAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSL 795 + QS + + ++ E L + LE+ +A + D Sbjct: 1456 KKVLEESHQSNAAGLLEKTNECAKLSTALKEREGRLQSLSQDVVSLEKQVAELTDLMKEK 1515 Query: 796 ERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKN 855 ER + S L+EKQ+ + L +VL ++EK+ L + + Sbjct: 1516 ERTVLEQSSQLEEKQQELWQLGDSIRVLQGEESVL--RSGILEKEALVQQTAEQSRLHLE 1573 Query: 856 QILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQ 915 Q+ L+++ Q+ + +++ E A E E K + L S L ++T +++ Sbjct: 1574 QVALQKSLTAQLEV-ELECVRRERSEAALHLQQKEEELNKERQSGLSLSSQLSQVTQKNE 1632 Query: 916 TL---IVQKKKEIEDLEIEFNTQIESAIRDKKVLNEK---YEKNIEYVTQLEAQLQEYKN 969 L + Q+K EI DL + K L E ++ E V QL+A+ Sbjct: 1633 LLARELEQRKAEITDLSDNVQALSQQRATFKSELRETGTALARSQEEVAQLKAECSRQ-- 1690 Query: 970 NIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALN 1029 E L + ++E ++ L K QQ + +L+ LL+QK +E ++L+ Sbjct: 1691 --EGLQVALQEKEQL---LRQKEALIQQMTASKA---------ELDQLLRQKTDEAVSLS 1736 Query: 1030 QKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQD 1089 + ++ Q S + E + +T +++++ + + L S E L+ ++++ Sbjct: 1737 TQTSDLQESIRRLRGQLERSALEVSTLQRSLQQKEESSLEGLSRSAAALETLRTDLQDKQ 1796 Query: 1090 DQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEE 1149 + LKE ++ + + + + E DD V +Q+ + Sbjct: 1797 AECLSLKEQLSHLRESVTELSSALRAQSTEV--DDLKRVLGQKDAALSDQGRC-LQDVQS 1853 Query: 1150 FIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTE 1209 E S+ + Q + +TEL QL +L+TE D + + +S L + Sbjct: 1854 RADEASLFKAQFME-STELVSQLQS--QLHSLSTECARLD----KSAGEAQSAFNNLKEK 1906 Query: 1210 NDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTE---HELRVQLSAFES 1266 L + + R +S QR E++ L KQ L + Q+ LR ++SA Sbjct: 1907 YATSLEELQDARGQLS----QRMEEVSSLQKQ-LEDSASQHQRAAGAVETLRSEISAVGR 1961 Query: 1267 KYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSE 1326 K E+ D S ++E+ E + S Q K+ + L+ ++ V Q+ +L Sbjct: 1962 KLERAEDLNSSLSREKE------EALASHQAKVSLLTVEIEKLKSQHVQVAAQVNVLTEN 2015 Query: 1327 IEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXX 1386 +E ++A L +E Q+ +++ ++ + EE A K+ Sbjct: 2016 LEQREMALHAINSQHSSQARRTS-QLLSEMQTLQEVNQR----LQEEMASAKEEHQKLLA 2070 Query: 1387 XXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEK 1446 R+ + + L +LE + + +++ T+ + E ++++ ++ +K Sbjct: 2071 ASSQENARLKEDAGRFLAEKEELEDRCHRLERQSSSLGETMARTTSERDDLQTKVSVQDK 2130 Query: 1447 RIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVA 1506 + L +N E + ++SE E + ++E E N+ V Sbjct: 2131 ELSQLK---------------DNVRKVEQILQDSEREWLLVLER------EKEEKNQLVE 2169 Query: 1507 ELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQ 1566 L ++E E++ + AL+ Q+++ +L +++ + +R S ++ AS ++ Sbjct: 2170 RLT-SVENEMSSKDVKVNALK-QDLD--SLQEKLALASSAIRQGSDQLGAKELEASASRL 2225 Query: 1567 GRDEQLDNTMNKELLDAVPRAELDLAMYMLHQ 1598 ++ L + KEL ++ + L A + LH+ Sbjct: 2226 QLEKLLASVQEKELDNSRLQQALGAAQHRLHR 2257 Score = 129 bits (311), Expect = 7e-28 Identities = 257/1382 (18%), Positives = 565/1382 (40%), Gaps = 93/1382 (6%) Query: 212 EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271 E ++++ + E + +E+ +L+ D++ + I SL++ LLE R EIS Sbjct: 751 ESLQREVDQTNEELDKLNTACLEERAQLIHDLQGCEREIDSLKDV--LLEKDR-EISALS 807 Query: 272 SKLAQELEQXXXXXXXXXXXXXXL--AKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIE 329 +++ EQ L + ++ + E + E S E ++ + + I+ Sbjct: 808 GHVSECTEQLSLLKHELKLKEQNLIQVENALSKAERELLLLRESRSSEQQSLED--RLIQ 865 Query: 330 LLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQL 389 L + L + K E++ ++ + A+ + + I G +M+S +L Sbjct: 866 LGDSLKDAQTELVKVREHR-DSLAAQVGALQEQAHQDEESILELRGE-VQKQMRSHGQRL 923 Query: 390 SSETLNQDTDKKINKNEIAKLE---MVIQSLNK--DLVDKEYVISEKDTXXXXXXXXXXG 444 S + + K KL+ + Q L+K + ++KE S+++ Sbjct: 924 SEGEAHITSLKDQLVAAAQKLQESSQLQQQLSKKEESLEKELKASKEERNRLHSQAEEYR 983 Query: 445 KDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEK 504 K+ QLE Q+ +G I G A ++ QL++ + + L + Sbjct: 984 KEAQTVSQQLEEQKRSQG---ITRGEMKATAETAAALEAQLREAEKERQR------LEAE 1034 Query: 505 LKSAEEQITQLNDEIDAANKNMIKVKS---NHKLKLKQMQKTIDNFSKVSDSNKEIVRLT 561 LK+ + + +L+ ++ + +N+ +++ + K + +Q+Q+ ++ ++ D KE VR Sbjct: 1035 LKTRDSEKEKLSSDLQSKAENISNLQNLLNSLKSEKQQLQEELEALTEELDLQKEKVR-- 1092 Query: 562 EELHHLSQKVAELEEEKGNLQ--LHLVDYDSGRMIES--DVYKKMIEMENLAETRLKAIS 617 LSQ+ A + + + Q + ++ R+ + + + + E+ AE+R +S Sbjct: 1093 ----QLSQEAASALDSRTSYQNQAQQLSAEAARLQQELDHLQRTLSELGCEAESRRDRVS 1148 Query: 618 LLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKE 677 +LE+Q + + +++ +E E+ +L S+ V + EQ+ A + E Sbjct: 1149 VLEAQ---VSENAAVIKALREEKEELTLQKQELSSEHVQGLASTA---EQLRRSLAERDE 1202 Query: 678 LALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLA 737 AL + D +Q + L+ + + +L +E++ ++ K + E ++ Sbjct: 1203 -ALADLQARADAQQK--ELTQLQEQERSLKTQLAE--KEHLGRENQSLKSEVGRQEEAVS 1257 Query: 738 KINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLER 797 K+ + +S + + +++ R+ + N++ E ++K + E+I + ++ L Sbjct: 1258 KLQSDAKSLQEKHSQVCQQMENREETLRNVKRECQQHKEELNVRNETIKSLTEQMGLLRG 1317 Query: 798 KADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQI 857 A +L S + +QK + Q L L R EK+L +LQ + + Sbjct: 1318 AAGELESGAELRQKELIQLHSQIQALTEDKQQLQAARRTTEKELALQSQRLCDLQGQLKE 1377 Query: 858 LLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNL-KRITHEHQT 916 LE+N +L L + Q AL E + + SE ++ L+ S L ++I + Q Sbjct: 1378 ALEQNSSLSAELGSLTQKNRALREDLAQKLESVSELAADRSALQQQLSGLEEQIAEDRQA 1437 Query: 917 L--IVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENL 974 +V++K+E+ E +E + + EK E +L L+E + +++L Sbjct: 1438 TDRLVKQKEELGSTVDELKKVLEESHQSNAA--GLLEKTNE-CAKLSTALKEREGRLQSL 1494 Query: 975 NMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINN 1034 + +V L K EL D +K++T + + ++ L++K +E+ L I Sbjct: 1495 SQDVVSLEKQVAELTDLMKEKERT------------VLEQSSQLEEKQQELWQLGDSIRV 1542 Query: 1035 AQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKE 1094 Q + S K A E +++V+ Q + Q EL+ + RE+ + Sbjct: 1543 LQGEESVLRSGILEKEALVQQTAEQSRLHLEQVALQKSLTAQLEVELECVRRERSEAALH 1602 Query: 1095 LKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQER 1154 L++ + E+N + G+ +SS + ++ + L + Q+R Sbjct: 1603 LQQKE--EELNKERQSGLSLSSQLSQVTQKNELLARELEQRKAEITDLS-DNVQALSQQR 1659 Query: 1155 SVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLL 1214 + + + + T L ++ QL+ + G V QE+ EQL + + L+ Sbjct: 1660 ATFKSELRETGTALARSQEEVAQLKAECSRQEGLQVALQEK--------EQLLRQKEALI 1711 Query: 1215 STVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQL--SAFE-SKYEQL 1271 + ++ + + Q+ E L+ + +D Q++ LR QL SA E S ++ Sbjct: 1712 QQMTASKAELDQLLRQKTDEAVS-----LSTQTSDLQESIRRLRGQLERSALEVSTLQRS 1766 Query: 1272 LDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEK 1331 L + S+ E ++ + + +L+ LQDK+ +L+E+ + + + L S + + Sbjct: 1767 LQQKEESSLEGLSR--SAAALETLRTDLQDKQAECLSLKEQLSHLRESVTELSSALRAQS 1824 Query: 1332 VAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNIN-EENAQLKKSSXXXXXXXXX 1390 R + E S+ E+ +L Sbjct: 1825 TEVDDLKRVLGQKDAALSDQGRCLQDVQSRADEASLFKAQFMESTELVSQLQSQLHSLST 1884 Query: 1391 XXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQL---VEYEKR 1447 R++ + + + L+ K + ++ + L+QR +E ++++QL +R Sbjct: 1885 ECARLDKSAGEAQSAFNNLKEKYATSLEELQDARGQLSQRMEEVSSLQKQLEDSASQHQR 1944 Query: 1448 IEDLTYEKESELAIL--RLKMHENANHYETMQKESEI-ERVKLIEELNVKITESVSLNKQ 1504 SE++ + +L+ E+ N + +KE + + L V+I + S + Q Sbjct: 1945 AAGAVETLRSEISAVGRKLERAEDLNSSLSREKEEALASHQAKVSLLTVEIEKLKSQHVQ 2004 Query: 1505 VAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDT 1564 VA L E + + A+ +Q ++ + ++ + ++Q+ ++ A + Sbjct: 2005 VAAQVNVLTENLEQREMALHAINSQHSSQARRTSQLLSEMQTLQEVNQRLQEEMASAKEE 2064 Query: 1565 KQ 1566 Q Sbjct: 2065 HQ 2066 Score = 122 bits (295), Expect = 6e-26 Identities = 278/1497 (18%), Positives = 599/1497 (40%), Gaps = 128/1497 (8%) Query: 155 DNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDT 214 +NA +V++ + E L QE +E Q + + + + Sbjct: 1156 ENA-AVIKALREEKEELTLQKQELSSEHVQGLASTAEQLRRSLAERDEALADLQARADAQ 1214 Query: 215 KQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKL 274 ++++T++QE +++ + EK+ L ++ +S + EEA L++ + +HS++ Sbjct: 1215 QKELTQLQEQERSLKTQLA-EKEHLGRENQSLKSEVGRQEEAVSKLQSDAKSLQEKHSQV 1273 Query: 275 AQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSL-----EIANMTELTKKIE 329 Q++E ++ + K+ E+ G L E+ + EL +K E Sbjct: 1274 CQQMENREETLRNVKRECQQHKEELNVRNETIKSLTEQMGLLRGAAGELESGAELRQK-E 1332 Query: 330 LLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISR-KSGRNTASKMKSPWSQ 388 L++ L+ QI+ ++ + A T K ++ S++ L + K S + + Sbjct: 1333 LIQ-LHSQIQALTEDKQQLQAARRTTEKELALQSQRLCDLQGQLKEALEQNSSLSAELGS 1391 Query: 389 LS--SETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKD 446 L+ + L +D +K+ +++L +L + L E I+E Sbjct: 1392 LTQKNRALREDLAQKL--ESVSELAADRSALQQQLSGLEEQIAEDRQATDRLVKQKEELG 1449 Query: 447 TLIAQLQ--LEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEK 504 + + +L+ LE L+ E NE AK+ LK+ ++ ++ L + Sbjct: 1450 STVDELKKVLEESHQSNAAGLL------EKTNECAKLSTALKE------REGRLQSLSQD 1497 Query: 505 LKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRL-TEE 563 + S E+Q+ +L D + + +++ S + K +++ + D+ +V + ++R E Sbjct: 1498 VVSLEKQVAELTDLMKEKERTVLEQSSQLEEKQQELWQLGDSI-RVLQGEESVLRSGILE 1556 Query: 564 LHHLSQKVAE---LEEEKGNLQLHL-----VDYDSGRMIESDVYKKMIEM-ENLAETRLK 614 L Q+ AE L E+ LQ L V+ + R S+ + + E L + R Sbjct: 1557 KEALVQQTAEQSRLHLEQVALQKSLTAQLEVELECVRRERSEAALHLQQKEEELNKERQS 1616 Query: 615 AISLLESQKFDLVQELHILQQKYDEVEDKLADIS-QLQS-DQVCSEIKSVHLEEQIDALS 672 +S L SQ + Q+ +L ++ ++ + ++ D+S +Q+ Q + KS L E AL+ Sbjct: 1617 GLS-LSSQLSQVTQKNELLARELEQRKAEITDLSDNVQALSQQRATFKS-ELRETGTALA 1674 Query: 673 ASKKELALV------IENLKL---DKEQLY----GTIKDLENDKEDIMNKLQNYIQE--- 716 S++E+A + E L++ +KEQL I+ + K ++ L+ E Sbjct: 1675 RSQEEVAQLKAECSRQEGLQVALQEKEQLLRQKEALIQQMTASKAELDQLLRQKTDEAVS 1734 Query: 717 ----NMDLTDKLEKM------SAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIEN 766 DL + + ++ SA ++S L + +E+S ++ A ++ +++ Sbjct: 1735 LSTQTSDLQESIRRLRGQLERSALEVSTLQRSLQQKEESSLEGLSRSAAALETLRTDLQD 1794 Query: 767 IESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNR 826 ++E K ++ L ES+ + + + D L L +K A S+ + + Sbjct: 1795 KQAECLSLKEQLSHLRESVTELSSALRAQSTEVDDLKRVLGQKDAALSD----QGRCLQD 1850 Query: 827 LAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRT 886 + D + + Q +E +LQ + L E L S + Q +N L EK T Sbjct: 1851 VQSRADEASLFKAQFMESTELVSQLQSQLHSLSTECARLDKSAGEAQSAFNNLKEK-YAT 1909 Query: 887 DLAESESTKYQTQLR-----DLESNLKRITHEHQT---LIVQKKKEIEDL--EIEFNTQI 936 L E + + Q R L+ L+ +HQ + + EI + ++E + Sbjct: 1910 SLEELQDARGQLSQRMEEVSSLQKQLEDSASQHQRAAGAVETLRSEISAVGRKLERAEDL 1969 Query: 937 ESAI-RDKKVLNEKYEKNIEYVT-QLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQ 994 S++ R+K+ ++ + +T ++E ++ +N+ E L + + L + Sbjct: 1970 NSSLSREKEEALASHQAKVSLLTVEIEKLKSQHVQVAAQVNVLTENLEQREMAL--HAIN 2027 Query: 995 KQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFT 1054 Q + T Q ++E+ L + ++ EE+ + ++ + + + +F Sbjct: 2028 SQHSSQARRTSQLLSEMQTLQEVNQRLQEEMASAKEEHQKLLAASSQENARLKEDAGRFL 2087 Query: 1055 TKLENMEEEMQRVSKQ-------LLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIP 1107 + E +E+ R+ +Q + + ++LQ V QD ++ +LK+ E + Sbjct: 2088 AEKEELEDRCHRLERQSSSLGETMARTTSERDDLQTKVSVQDKELSQLKDNVRKVEQILQ 2147 Query: 1108 KTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTE 1167 +E + +E ++ N + V + Q+ LQE+ A ++ Sbjct: 2148 DSEREWL-LVLEREKEEKNQLVERLTSVENEMSSKDV-KVNALKQDLDSLQEKLALASSA 2205 Query: 1168 LQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSA 1227 +++ QL E + ++ Q+ +L + +++ +N L + + + Sbjct: 2206 IRQGSD---QLGAKELEAS----ASRLQLEKLLASVQEKELDNSRLQQALGAAQHRLHRL 2258 Query: 1228 VDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIV 1287 + ++GF H Q D L ++ E + +D+++S E NK V Sbjct: 2259 LQKKGFSAG---APH--QSPPDLSAAAACLHTMITQLEEGQQGQVDTLRS----EVNKSV 2309 Query: 1288 TMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDE----KVAFXXXXXXXXX 1343 + Q KL++ E +++ A + ++E+L+S++ + A Sbjct: 2310 A--DLERTQEKLEEAERRSEQKEQEAAGLQTEVELLQSQLHAQVDITNQAAAKLERLSSQ 2367 Query: 1344 XXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVL 1403 R Q +Q Q+Q +++ + AQ +S + + V Sbjct: 2368 LQEKGDQISRMSVQLQQQQQQQQLVDKDAAVAQAMESQANQESVLAQLESLQQEHQRSVK 2427 Query: 1404 ELTHQLE--LKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAI 1461 LE K ++ + L+++ + Q L+E +E L + A Sbjct: 2428 RREQILEQKAKSEQLRSEKQLLESALSEKEERLSQAVQTLMEKSSVLEQLQASAAQKDAA 2487 Query: 1462 LRLKMHENANHYETMQKESEIE------RVKLIEELNVKITESVSLNKQVAELNKALEEE 1515 + + + +QKE + E +L +EL E L ++V A +E Sbjct: 2488 FEQERKDWMQKLDQLQKELQKESTSPSASAELGKELAQVRLEKTKLERKVQAALLARKEA 2547 Query: 1516 VAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQL 1572 + K E + AL + + + +++ +L+ + R++ S Q ++ Q RDE L Sbjct: 2548 MKKAEEQERALTQELTGLRSFEEKVRDLEEL-RSTCSSDQDELAALRQLLQERDESL 2603 Score = 107 bits (257), Expect = 2e-21 Identities = 206/1022 (20%), Positives = 437/1022 (42%), Gaps = 98/1022 (9%) Query: 628 QELHILQQKYDEVEDKLADISQLQS-DQVCSEIKSVHLEEQIDALSASKKEL--ALVIEN 684 Q L + Q + ++++ +LA QS D ++ L +Q+ L+ +++ L +LV + Sbjct: 608 QRLWVSQNELEKLQSQLASARHQQSRDAEKHQLLVTSLNQQLKGLTDTQESLESSLVEKE 667 Query: 685 LKLDKE----QLYGTIKDLENDKE-DIMNKLQNYIQENMDLTDKLEKMSA--EKISELLA 737 L + +L ++++ + KE + +Q L +K S ++ SEL A Sbjct: 668 TALARTCQQLELVSSLQEALSLKELQLREASDKLLQAEHSLDSIWQKCSGSEKQCSELKA 727 Query: 738 KINHEEQSKIQTQFGI-DAKIQERDLYIENIESELSKYKSRICRL-----EESIAVMEDR 791 ++ + + + G+ K Q++++ IE+++ E+ + + +L EE ++ D Sbjct: 728 EV-----ADLTQKLGVLKEKTQKQEVTIESLQREVDQTNEELDKLNTACLEERAQLIHDL 782 Query: 792 RYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKEL 851 + ER+ D L L EK + S + E +L++L ++ E+ L+++E+ + Sbjct: 783 Q-GCEREIDSLKDVLLEKDREISALSGHVSECTEQLSLLKHELKLKEQNLIQVENALSKA 841 Query: 852 QKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRIT 911 +++ +L E + Q SL D ++ A +T+L + +++ L L+ Sbjct: 842 ERELLLLRESRSSEQQSLEDRLIQLGDSLKDA-QTELVKVR--EHRDSLAAQVGALQEQA 898 Query: 912 HEHQTLIVQKKKEIEDLEIEFNTQI---ESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYK 968 H+ + I++ + E++ ++ E+ I K + ++ +QL+ QL + + Sbjct: 899 HQDEESILELRGEVQKQMRSHGQRLSEGEAHITSLKDQLVAAAQKLQESSQLQQQLSKKE 958 Query: 969 NNIEN-LNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIA 1027 ++E L + EE N+++ + +++ ++ QT S EQ ++ +K E A Sbjct: 959 ESLEKELKASKEERNRLHSQA-EEYRKEAQTVSQQLEEQKRSQ-GITRGEMKATAETAAA 1016 Query: 1028 LNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVRE 1087 L ++ A E + + +L+ + E +++S L ++ LQ L+ Sbjct: 1017 LEAQLREA-----------EKERQRLEAELKTRDSEKEKLSSDLQSKAENISNLQNLLNS 1065 Query: 1088 QDDQIKELKET--KLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQ 1145 + ++L+E LT E+++ K + + +S +A + L Sbjct: 1066 LKSEKQQLQEELEALTEELDLQKEK-------VRQLSQEAASALDSRTSYQNQAQQLSA- 1117 Query: 1146 EEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQ 1205 E QE LQ ++L E + ++ LE +E +E+ +L + ++ Sbjct: 1118 EAARLQQELDHLQRTLSELGCEAESRRDRVSVLEAQVSENAAVIKALREEKEELTLQKQE 1177 Query: 1206 LNTEN-DNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQRE--ADFQKTEHELRVQLS 1262 L++E+ L ST +LR S++ +R +A+L + AQ++ Q+ E L+ QL+ Sbjct: 1178 LSSEHVQGLASTAEQLRRSLA----ERDEALADLQARADAQQKELTQLQEQERSLKTQLA 1233 Query: 1263 AFE--SKYEQLLDSVQSSTQEETNKIVT-----MEQVTSLQNKLQDKEEHLRNLQEKYAD 1315 E + Q L S +E +K+ + E+ + + +++++EE LRN++ + Sbjct: 1234 EKEHLGRENQSLKSEVGRQEEAVSKLQSDAKSLQEKHSQVCQQMENREETLRNVKRECQQ 1293 Query: 1316 VINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENA 1375 ++ + I+ + +LR + Q Q++ E+ Sbjct: 1294 HKEELNVRNETIKS--LTEQMGLLRGAAGELESGAELRQKELIQLHSQIQAL---TEDKQ 1348 Query: 1376 QLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQ---LELKDSEIYQKTHEYTITLTQRND 1432 QL+ + R+ D + ++ E Q L + + QK L Q+ + Sbjct: 1349 QLQAARRTTEKELALQSQRLCDLQGQLKEALEQNSSLSAELGSLTQKNRALREDLAQKLE 1408 Query: 1433 EFENV-------RQQLVEYEKRI-ED------LTYEKE---SELAILRLKMHEN--ANHY 1473 + +QQL E++I ED L +KE S + L+ + E+ +N Sbjct: 1409 SVSELAADRSALQQQLSGLEEQIAEDRQATDRLVKQKEELGSTVDELKKVLEESHQSNAA 1468 Query: 1474 ETMQKESEIERVKL-IEELNVKIT----ESVSLNKQVAELNKALEEEVAKTNEMQTALEN 1528 ++K +E ++ ++E ++ + VSL KQVAEL ++E+ E + LE Sbjct: 1469 GLLEKTNECAKLSTALKEREGRLQSLSQDVVSLEKQVAELTDLMKEKERTVLEQSSQLEE 1528 Query: 1529 QEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAE 1588 ++ E+ L D I LQ S I + + T + L+ ++ L A E Sbjct: 1529 KQQELWQLGDSIRVLQGEESVLRSGILEKEALVQQTAEQSRLHLEQVALQKSLTAQLEVE 1588 Query: 1589 LD 1590 L+ Sbjct: 1589 LE 1590 Score = 104 bits (249), Expect = 2e-20 Identities = 223/1210 (18%), Positives = 493/1210 (40%), Gaps = 91/1210 (7%) Query: 387 SQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKD 446 SQL+S Q D + ++ + L ++ L E + EK+T Sbjct: 622 SQLASARHQQSRDAEKHQLLVTSLNQQLKGLTDTQESLESSLVEKETALARTCQQLELVS 681 Query: 447 TLIAQLQLEHQQHMEGPS-LIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKL 505 +L L L+ Q E L+ + + + + E+ EL E+ D+ K + K Sbjct: 682 SLQEALSLKELQLREASDKLLQAEHSLDSIWQKCSGSEKQCSELKAEVADLTQKLGVLKE 741 Query: 506 KSAEEQIT---------QLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKV-SDSNK 555 K+ ++++T Q N+E+D N ++ ++ L+ ++ ID+ V + ++ Sbjct: 742 KTQKQEVTIESLQREVDQTNEELDKLNTACLEERAQLIHDLQGCEREIDSLKDVLLEKDR 801 Query: 556 EIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKA 615 EI L+ + +++++ L+ E + +L+ +E+ + K E+ L E+R Sbjct: 802 EISALSGHVSECTEQLSLLKHELKLKEQNLI------QVENALSKAERELLLLRESRSSE 855 Query: 616 ISLLESQKFDLVQELHILQQ---KYDEVEDKL-ADISQLQSDQVCSEIKSVHLEEQID-A 670 LE + L L Q K E D L A + LQ E + L ++ Sbjct: 856 QQSLEDRLIQLGDSLKDAQTELVKVREHRDSLAAQVGALQEQAHQDEESILELRGEVQKQ 915 Query: 671 LSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAE 730 + + + L+ ++ K+QL + L+ ++LQ + + + +K K S E Sbjct: 916 MRSHGQRLSEGEAHITSLKDQLVAAAQKLQES-----SQLQQQLSKKEESLEKELKASKE 970 Query: 731 KISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMED 790 + + L ++ E + + QT + +++E+ E+ LE + E Sbjct: 971 ERNRLHSQA-EEYRKEAQT---VSQQLEEQKRSQGITRGEMKATAETAAALEAQLREAEK 1026 Query: 791 RRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLL-EIEHENK 849 R LE +L + EK+K S+ + + + N L L++ + ++QL E+E + Sbjct: 1027 ERQRLEA---ELKTRDSEKEKLSSDLQSKAENISN-LQNLLNSLKSEKQQLQEELEALTE 1082 Query: 850 ELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKR 909 EL + + + + +Q +L D + Y N+ +E+ + Q +L L+ L Sbjct: 1083 ELDLQKEKVRQLSQEAASAL-DSRTSYQ------NQAQQLSAEAARLQQELDHLQRTLSE 1135 Query: 910 ITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKK--VLNEKYEKNIEYVTQLEAQLQEY 967 + E ++ + + + + ++ N + A+R++K + +K E + E+V L + ++ Sbjct: 1136 LGCEAESR--RDRVSVLEAQVSENAAVIKALREEKEELTLQKQELSSEHVQGLASTAEQL 1193 Query: 968 KNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIA 1027 + ++ + + +L + + K + + Q Q Q + E L + E+ Sbjct: 1194 RRSLAERDEALADL-QARADAQQKELTQLQEQERSLKTQ-LAEKEHLGRENQSLKSEVGR 1251 Query: 1028 LNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQI---L 1084 + ++ Q S+ + K +Q ++EN EE ++ V + + +QH EEL + Sbjct: 1252 QEEAVSKLQSDAKSL----QEKHSQVCQQMENREETLRNVKR---ECQQHKEELNVRNET 1304 Query: 1085 VREQDDQIKELKET--KLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXL 1142 ++ +Q+ L+ +L + + E + + S I+ +++D + L Sbjct: 1305 IKSLTEQMGLLRGAAGELESGAELRQKELIQLHSQIQALTEDKQQLQ-AARRTTEKELAL 1363 Query: 1143 KVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQL-ETL--NTELTGHDVVNQEQINQL 1199 + Q + + EQ++ L+ EL K L E L E ++ + Q Sbjct: 1364 QSQRLCDLQGQLKEALEQNSSLSAELGSLTQKNRALREDLAQKLESVSELAADRSALQQQ 1423 Query: 1200 KSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEH--EL 1257 S LE+ E+ + + + + S VD+ + E H + +KT +L Sbjct: 1424 LSGLEEQIAEDRQATDRLVKQKEELGSTVDELKKVLEE---SHQSNAAGLLEKTNECAKL 1480 Query: 1258 RVQLSAFESKYEQLLDSVQSSTQE--ETNKIVTMEQVTSLQ--NKLQDKEEHLRNLQEKY 1313 L E + + L V S ++ E ++ ++ T L+ ++L++K++ L L + Sbjct: 1481 STALKEREGRLQSLSQDVVSLEKQVAELTDLMKEKERTVLEQSSQLEEKQQELWQLGDSI 1540 Query: 1314 ADVINQIEILRSEIEDEKVAFXXXXXXX------XXXXXXXXXDLRTENQSYKQMQEQSI 1367 + + +LRS I +++ L E + ++ + ++ Sbjct: 1541 RVLQGEESVLRSGILEKEALVQQTAEQSRLHLEQVALQKSLTAQLEVELECVRRERSEAA 1600 Query: 1368 LNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITL 1427 L++ ++ +L K +++ K L +LE + +EI + Sbjct: 1601 LHLQQKEEELNKE----RQSGLSLSSQLSQVTQKNELLARELEQRKAEITDLSDNVQALS 1656 Query: 1428 TQR---NDEFENVRQQLVEYEKRIEDLTYE--KESELAILRLKMHENANHYETMQKESEI 1482 QR E L ++ + L E ++ L + + + E + ++ Sbjct: 1657 QQRATFKSELRETGTALARSQEEVAQLKAECSRQEGLQVALQEKEQLLRQKEALIQQMTA 1716 Query: 1483 ERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITN 1542 + +L + L K E+VSL+ Q ++L +++ + ++ALE ++ E ++ Sbjct: 1717 SKAELDQLLRQKTDEAVSLSTQTSDLQESIRR--LRGQLERSALEVSTLQRSLQQKEESS 1774 Query: 1543 LQNMVRASSS 1552 L+ + R++++ Sbjct: 1775 LEGLSRSAAA 1784 Score = 100 bits (239), Expect = 4e-19 Identities = 242/1257 (19%), Positives = 522/1257 (41%), Gaps = 126/1257 (10%) Query: 147 LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXX 206 L I E A L + + + +T+ +L++ + E Q A T Sbjct: 1427 LEEQIAEDRQATDRLVKQKEELGSTVDELKKVLEESHQSNAAGLLEKTNECAKLSTALKE 1486 Query: 207 XXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKD---IESKDVRISSLEEANKLLEAA 263 + Q + +++ + K++++ +L+ +E K + L ++ ++L+ Sbjct: 1487 REGRLQSLSQDVVSLEKQVAELTDLMKEKERTVLEQSSQLEEKQQELWQLGDSIRVLQGE 1546 Query: 264 RFEIS---LEHSKLAQEL-EQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIA 319 + LE L Q+ EQ A+ +E C + E L+ Sbjct: 1547 ESVLRSGILEKEALVQQTAEQSRLHLEQVALQKSLTAQLEVELECVRRERSEAALHLQ-Q 1605 Query: 320 NMTELTKKIELLEHLNCQIRQTN-------KELENKLATMGTESKAVSSPSKKGSPLISR 372 EL K+ + L+ Q+ Q +ELE + A + S V + S++ + S Sbjct: 1606 KEEELNKERQSGLSLSSQLSQVTQKNELLARELEQRKAEITDLSDNVQALSQQRATFKSE 1665 Query: 373 KSGRNTA-SKMKSPWSQLSSETLNQD-TDKKINKNE--IAKLEMVIQSLNKDLVDKEYVI 428 TA ++ + +QL +E Q+ + + E + + E +IQ + + + ++ Sbjct: 1666 LRETGTALARSQEEVAQLKAECSRQEGLQVALQEKEQLLRQKEALIQQMTASKAELDQLL 1725 Query: 429 SEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVG------TNTEDVNEIAKVQ 482 +K I +L+ + ++ S + ++ E ++ A Sbjct: 1726 RQKTDEAVSLSTQTSDLQESIRRLRGQLERSALEVSTLQRSLQQKEESSLEGLSRSAAAL 1785 Query: 483 EQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVK----------SN 532 E L+ +L D K L E+L E +T+L+ + A + + +K S+ Sbjct: 1786 ETLRTDLQD--KQAECLSLKEQLSHLRESVTELSSALRAQSTEVDDLKRVLGQKDAALSD 1843 Query: 533 HKLKLKQMQKTIDNFS----KVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDY 588 L+ +Q D S + +S + + +L +LH LS + A L++ G Q + Sbjct: 1844 QGRCLQDVQSRADEASLFKAQFMESTELVSQLQSQLHSLSTECARLDKSAGEAQSA---F 1900 Query: 589 DSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADIS 648 ++ + + +++ + R++ +S L+ Q D + H Q+ VE ++IS Sbjct: 1901 NNLKEKYATSLEELQDARGQLSQRMEEVSSLQKQLEDSASQ-H--QRAAGAVETLRSEIS 1957 Query: 649 QL-QSDQVCSEIKSVHLEEQIDALSASKKELALV---IENLKLDKEQLYGTIKDLENDKE 704 + + + ++ S E+ +AL++ + +++L+ IE LK Q+ + L + E Sbjct: 1958 AVGRKLERAEDLNSSLSREKEEALASHQAKVSLLTVEIEKLKSQHVQVAAQVNVLTENLE 2017 Query: 705 DIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYI 764 L ++ + ++ +E + L ++N Q ++ + AK + + L Sbjct: 2018 QREMALHAINSQHSSQARRTSQLLSEM--QTLQEVNQRLQEEMAS-----AKEEHQKLLA 2070 Query: 765 ENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYL----QEKQKAYSEYTIQE 820 + + E ++ K R +EDR + LER++ LG + E+ ++ ++Q+ Sbjct: 2071 ASSQ-ENARLKEDAGRFLAEKEELEDRCHRLERQSSSLGETMARTTSERDDLQTKVSVQD 2129 Query: 821 DELVNRLAVLMDHDRVVEKQLLEIEHE-----NKELQKKNQILLEENQNLQISLSDMQQH 875 E L+ L D+ R VE+ L + E E +E ++KNQ L+E +++ +S Sbjct: 2130 KE----LSQLKDNVRKVEQILQDSEREWLLVLEREKEEKNQ-LVERLTSVENEMSSKDVK 2184 Query: 876 YNALVEKAN----RTDLAESESTKYQTQL--RDLESNLKRITHEHQTLIVQKKKEIEDLE 929 NAL + + + LA S + QL ++LE++ R+ E VQ +KE+++ Sbjct: 2185 VNALKQDLDSLQEKLALASSAIRQGSDQLGAKELEASASRLQLEKLLASVQ-EKELDNSR 2243 Query: 930 IEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELI 989 ++ + +A L +K + Q L + + +EE + ++ + Sbjct: 2244 LQ--QALGAAQHRLHRLLQKKGFSAGAPHQSPPDLSAAAACLHTMITQLEEGQQGQVDTL 2301 Query: 990 DKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQV---SYMSMVSDY 1046 V K + T++ + E + + +QK++E L ++ Q + + + + Sbjct: 2302 RSEVNK-SVADLERTQEKLEEAERRS---EQKEQEAAGLQTEVELLQSQLHAQVDITNQA 2357 Query: 1047 ESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNI 1106 +KL + +++L+ +++ R+S QL Q ++ Q LV ++D + + E++ E + Sbjct: 2358 AAKLERLSSQLQEKGDQISRMSVQL----QQQQQQQQLV-DKDAAVAQAMESQANQESVL 2412 Query: 1107 PKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNT 1166 + E + + +V +++ E++ ++ S L E+ +L+ Sbjct: 2413 AQLESL--------QQEHQRSVKRREQILEQKAKSEQLRSEKQLLE--SALSEKEERLSQ 2462 Query: 1167 ELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTE---NDNLLSTVAELRSS 1223 +Q K LE L D +++ KL+QL E S AEL Sbjct: 2463 AVQTLMEKSSVLEQLQASAAQKDAAFEQERKDWMQKLDQLQKELQKESTSPSASAELGKE 2522 Query: 1224 ISSAVDQRGFEIAELWKQHLAQREA--DFQKTEHELRVQLSAFESKYEQL--LDSVQSST 1279 ++ ++ ++ LA++EA ++ E L +L+ S E++ L+ ++S+ Sbjct: 2523 LAQVRLEKTKLERKVQAALLARKEAMKKAEEQERALTQELTGLRSFEEKVRDLEELRSTC 2582 Query: 1280 QEETNKIVTMEQVTSLQNKLQDKEEHLRNL-----QEKYADVINQIEILRSEIEDEK 1331 + +++ + Q+ LQ+++E LR+L Q + A + N L+ E+ED K Sbjct: 2583 SSDQDELAALRQL------LQERDESLRDLKLSLDQHQSASLAN----LKEELEDLK 2629 Score = 99 bits (238), Expect = 5e-19 Identities = 197/1113 (17%), Positives = 449/1113 (40%), Gaps = 76/1113 (6%) Query: 445 KDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEK 504 K+ L ++L+ QQ S H +E A++Q + + + K + ++ Sbjct: 2808 KEELRPAVELQLQQQ----SRAHHAWMERAKSEAAELQRSQQHPQDGQSKMAALTRKLQA 2863 Query: 505 LKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKV-----SDSNKEIVR 559 + +++ + N + K + + + +++L ++ ++ + + ++K+ V Sbjct: 2864 ALLSRKELMKENSALKQDAKRLAEKEHAKEVELSALEAALEEVKREKRELETSASKDKVE 2923 Query: 560 LTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLL 619 L E+ L + L G+L+L + + + S ++E L +++ + +S Sbjct: 2924 LRGEMDRLLSENHSLSAACGSLKLTIENMGQQKEAFS------CQLEALKDSQAEELSRW 2977 Query: 620 ESQKFDLVQELHILQQKYDEVE---DKLADISQLQSDQVCSEIKSVH-LEEQIDALSASK 675 SQ +L Q+ L + Y D + + + ++ H LE + DAL Sbjct: 2978 RSQHAELKQQHESLLRSYQSTGAQMDAMRHVLEATERDALEAVRKSHRLETERDALEKQA 3037 Query: 676 KELA----LVIENLKLDKEQLYGTIKDLENDKEDIMNKL----QNYIQENMDLTDKLEKM 727 +EL + E + + T+++LE +K++ +L +N+ +E +L +++ Sbjct: 3038 RELEGEHDRIKERMHTFSREKQWTVEELEREKQNSRRRLRELEENHSREASELGHANQQL 3097 Query: 728 SAEKISELLAKINH--EEQSKIQTQFGIDAK-IQERDLYIENIESELSKYKSRI-CRLEE 783 AE I L A E+ S++Q++ A+ +QE +E +E + +S + +LEE Sbjct: 3098 EAE-ICRLRASAEELGEKLSELQSENKRMAQELQESSCTLEERSAESERSRSSLQLQLEE 3156 Query: 784 SIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLE 843 ++ ME + L + + +EKQ + EL + A++ + VV + E Sbjct: 3157 ALGRMETQTTELGAQVELNNLLQKEKQNLSQHMEAMQTELGKKEALIQELQEVVSRHSQE 3216 Query: 844 IEHENKE---LQKKNQILLEENQNLQISLSDM--QQHY--NALVEKANRTDLAESESTKY 896 N++ L+ +L EE +N+Q + + ++ Y L++ + + D Sbjct: 3217 TVSLNEKVRILEDDKSLLQEELENVQETSDKVKNEKEYLETVLLQNSEKVDELTESVAVL 3276 Query: 897 QTQLRDLESNLKRITHEHQTLIVQKKKE----IEDLEIEFNTQIESAIRDKKVLNEKYEK 952 Q+Q +L S L +H + + +K++E + +LE + ++ + K +N++ ++ Sbjct: 3277 QSQNLELNSQLAASSHTNHRVRQEKEEEQLRLVRELEEKLRA-VQRGSQGSKTINKELQE 3335 Query: 953 NIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEIN 1012 ++ Q QLQ+ + + + +E +K + +++ +Q++ +S + + + Sbjct: 3336 LLKEKHQEINQLQQNCIRYQEVILQLESSSKSSQAAVEQ-LQRELEKSSEQLSAVRQKCS 3394 Query: 1013 KLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLL 1072 + A L ++ + QK A+ D E+ E + K+ + Sbjct: 3395 RAEAELSEQRNLLQQAQQKRPGAESQRDPTALDLSHPSRSSEGHRESQPAE--KADKEAV 3452 Query: 1073 DSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXX 1132 +Q +L + ++ +++ELK+ + ++ + EG + SS + + A Sbjct: 3453 -LQQQMAQLVLSKDQESKKVQELKQQLDSGDVELKALEGALRSSEAKLSALSARPAGPEA 3511 Query: 1133 XXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVN 1192 E+ + ++ SV++ + + +E + L + + V Sbjct: 3512 SSLWTQVHQQAGSEDHQLLEPGSVIKRSLQNIRVKEKEMDELRLTHLKLQRTIDQYSVAA 3571 Query: 1193 QEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQK 1252 Q QL L N + + + +S+ VD+ E +L ++ L+ RE + Sbjct: 3572 AAQQRQL-FVLSANNADVCERAELMGAQVTELSAQVDRLEKE-KDLLRRQLSDREDAVCQ 3629 Query: 1253 TEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQE- 1311 T+ +L+ +++ + L + + + T+ LQ K+ + +L Sbjct: 3630 TQLQLQ------QAQKRRCLQAASERLEGLAAHLKTL---------LQSKDAEISSLLSC 3674 Query: 1312 KYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNIN 1371 K A + ++ L++ + A+ LR + +Q Q + Sbjct: 3675 KDAQMSGYLQQLQANGRSQAAAYEARLAALGHQREAAAGQLRGLQAKVRHLQVQVDTSSQ 3734 Query: 1372 EENAQLKKSSXXXXXXXXXXXXRVN-DAEAKVLELTHQLELK--DSE------IYQKTHE 1422 E K R + + LE ++L L+ D E + Q+ + Sbjct: 3735 ESQQAAAKMDAFRKSMAALQSERERLVSRCRTLETENRLGLRGPDGEGGASKGLKQEIRK 3794 Query: 1423 YTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEI 1482 + N E +R QLV Y + + + K+ +L +L K + + E + +E Sbjct: 3795 LLNQMDDLNSENAMLRAQLVRYREDLNQVLSLKDDQLKLLLQKQQDAIRNLEQQKAAAEE 3854 Query: 1483 ERVKLIEELNVKITESVSLNKQVAELNKALEEE 1515 ++ + ++ K ES +L Q+A +A EEE Sbjct: 3855 QQREARLQVQQKEEESEALRAQLAR-ERAQEEE 3886 Score = 92.3 bits (219), Expect = 1e-16 Identities = 267/1449 (18%), Positives = 563/1449 (38%), Gaps = 114/1449 (7%) Query: 147 LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXX 206 ++ T E+D+ LQ K+ + + + L++ + + +QI++ + Sbjct: 2111 MARTTSERDD----LQTKVSVQDKELSQLKDNVRKVEQILQDSEREWLLVLEREKEEKNQ 2166 Query: 207 XXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFE 266 + +M+ A++ + +++L + S +R S + K LEA+ Sbjct: 2167 LVERLTSVENEMSSKDVKVNALKQDLDSLQEKLA--LASSAIRQGSDQLGAKELEASASR 2224 Query: 267 ISLEHSKLA-QELE-QXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTEL 324 + LE + QE E L + + + L A Sbjct: 2225 LQLEKLLASVQEKELDNSRLQQALGAAQHRLHRLLQKKGFSAGAPHQSPPDLSAAAACLH 2284 Query: 325 TKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKS 384 T +L E Q+ E+ +A + + + ++ +G T ++ Sbjct: 2285 TMITQLEEGQQGQVDTLRSEVNKSVADLERTQEKLEEAERRSEQKEQEAAGLQTEVELLQ 2344 Query: 385 PWSQLSSETLNQDTDK--KINKNEIAKLEMVIQ-SLNKDLVDKEYVISEKDTXXXXXXXX 441 + NQ K +++ K + + + S+ ++ + +KD Sbjct: 2345 SQLHAQVDITNQAAAKLERLSSQLQEKGDQISRMSVQLQQQQQQQQLVDKDAAVAQAMES 2404 Query: 442 XXGKDTLIAQLQLEHQQHMEG----PSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVN 497 +++++AQL+ Q+H ++ +E + ++ E E + + Sbjct: 2405 QANQESVLAQLESLQQEHQRSVKRREQILEQKAKSEQLRSEKQLLESALSEKEERLSQA- 2463 Query: 498 VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKL-KQMQKTIDNFSKVSDSNKE 556 V+ L+EK S EQ+ + DAA + K +L K++QK + S ++ KE Sbjct: 2464 VQTLMEK-SSVLEQLQASAAQKDAAFEQERKDWMQKLDQLQKELQKESTSPSASAELGKE 2522 Query: 557 IVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIE-MENLAETRLKA 615 + ++ E L +KV + + + E + E + +L E R Sbjct: 2523 LAQVRLEKTKLERKVQAALLARKEAMKKAEEQERALTQELTGLRSFEEKVRDLEELR--- 2579 Query: 616 ISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVH-LEEQIDALS-- 672 S S + +L +LQ++ + + D + Q QS + + + + L+ Q LS Sbjct: 2580 -STCSSDQDELAALRQLLQERDESLRDLKLSLDQHQSASLANLKEELEDLKSQNGHLSEE 2638 Query: 673 -ASKKELALVIENLK--LDKEQLYGTIKDLEN------DKEDIMNKLQNYIQENMDLTDK 723 ASK+E +V E LD + L ++ LE DK + + K Q ++ +LT + Sbjct: 2639 LASKEEALMVGEQRAQALDSK-LLTVVEHLETAQAELRDKSEQVEKHQEALRAQ-ELTAE 2696 Query: 724 LEKMSAEKISELLAKINHEEQSKI-QTQFGIDAKIQERD---LYIENIESELSKYKSRIC 779 EK + E +LL EE+ + + Q +D +E+ I ++ EL +++ Sbjct: 2697 QEKGALESQLDLLTSALEEERRRCAEQQSRLDLSEREQAGAATLIRQLKDELGAGGTKLA 2756 Query: 780 RLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEK 839 + ++ ++ DQ G+ +Q+ +QED + A LM ++ EK Sbjct: 2757 QFDK----VKTCDVCKSGPDDQQGACFSCQQRE----KLQEDLKERQEAFLMSRAQLSEK 2808 Query: 840 QLLE--IEHENKELQKKNQILLEENQNLQISLSDMQQHYN-------ALVEKANRTDLAE 890 + L +E + ++ + + +E ++ L QQH AL K L+ Sbjct: 2809 EELRPAVELQLQQQSRAHHAWMERAKSEAAELQRSQQHPQDGQSKMAALTRKLQAALLSR 2868 Query: 891 SESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKY 950 E K + L+ L H + + + +E+++ E SA +DK L + Sbjct: 2869 KELMKENSALKQDAKRLAEKEHAKEVELSALEAALEEVKREKRELETSASKDKVELRGEM 2928 Query: 951 EKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINE 1010 ++ + L A K IEN+ E + LE + D + ++ Sbjct: 2929 DRLLSENHSLSAACGSLKLTIENMGQQKEAFS-CQLEAL-----------KDSQAEELSR 2976 Query: 1011 INKLNALLKQKDEEIIALNQKINNAQVSYMSMVSD-YESKLAQFTTKLENMEEEMQRVSK 1069 +A LKQ+ E ++ Q AQ+ M V + E + K +E E + K Sbjct: 2977 WRSQHAELKQQHESLLRSYQS-TGAQMDAMRHVLEATERDALEAVRKSHRLETERDALEK 3035 Query: 1070 QLLDSK-QHN---EELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDA 1125 Q + + +H+ E + RE+ ++EL+ K + + E E S +A Sbjct: 3036 QARELEGEHDRIKERMHTFSREKQWTVEELEREKQNSRRRLRELE--------ENHSREA 3087 Query: 1126 NNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQE--CYTKIIQLETLNT 1183 + + L+ EE ++ S LQ ++ ++ ELQE C + E+ + Sbjct: 3088 SELGHANQQLEAEICRLRA-SAEELGEKLSELQSENKRMAQELQESSCTLEERSAESERS 3146 Query: 1184 ELTGHDVVNQEQINQLKSKLEQL--NTENDNLL----STVAELRSSISSAVDQRGFEIAE 1237 + + +E + +++++ +L E +NLL +++ ++ + + ++ I E Sbjct: 3147 R-SSLQLQLEEALGRMETQTTELGAQVELNNLLQKEKQNLSQHMEAMQTELGKKEALIQE 3205 Query: 1238 LWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQN 1297 L ++ +++ + ++R+ L +S ++ L++VQ ++ + N+ +E V LQN Sbjct: 3206 L-QEVVSRHSQETVSLNEKVRI-LEDDKSLLQEELENVQETSDKVKNEKEYLETVL-LQN 3262 Query: 1298 --KLQDKEEHLRNLQEKYADVINQIEI-------LRSEIEDEKVAFXXXXXXXXXXXXXX 1348 K+ + E + LQ + ++ +Q+ +R E E+E++ Sbjct: 3263 SEKVDELTESVAVLQSQNLELNSQLAASSHTNHRVRQEKEEEQLRLVRELEEKLRAVQRG 3322 Query: 1349 XXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQ 1408 +T N+ +++ ++ IN QL+++ ++A V +L + Sbjct: 3323 SQGSKTINKELQELLKEKHQEIN----QLQQNCIRYQEVILQLESSSKSSQAAVEQLQRE 3378 Query: 1409 LELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHE 1468 LE K SE + E N+ QQ + E +++ L Sbjct: 3379 LE-KSSEQLSAVRQKCSRAEAELSEQRNLLQQAQQKRPGAES---QRDPTALDLSHPSRS 3434 Query: 1469 NANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALEN 1528 + H E+ E + L +++ + +K+V EL + L+ + ++ AL + Sbjct: 3435 SEGHRESQPAEKADKEAVLQQQMAQLVLSKDQESKKVQELKQQLDSGDVELKALEGALRS 3494 Query: 1529 QEIEIVTLN 1537 E ++ L+ Sbjct: 3495 SEAKLSALS 3503 Score = 83.8 bits (198), Expect = 4e-14 Identities = 258/1477 (17%), Positives = 585/1477 (39%), Gaps = 114/1477 (7%) Query: 148 SNTIKEKDNALSVLQVKMKIMETTILDLQEK-------INEKDQIIEAKNKATTXXXXXX 200 S+ +EK+ AL+ Q K+ ++ I L+ + +N + +E + A Sbjct: 1971 SSLSREKEEALASHQAKVSLLTVEIEKLKSQHVQVAAQVNVLTENLEQREMALHAINSQH 2030 Query: 201 XXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLL 260 + Q + ++ + A K+E Q+LL ++ R+ E+A + L Sbjct: 2031 SSQARRTSQLLSEM-QTLQEVNQRLQEEMASAKEEHQKLLAASSQENARLK--EDAGRFL 2087 Query: 261 -EAARFE-----ISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQ--SIEPSCEEKTEIEE 312 E E + + S L + + + K+ ++ + + +I + Sbjct: 2088 AEKEELEDRCHRLERQSSSLGETMARTTSERDDLQTKVSVQDKELSQLKDNVRKVEQILQ 2147 Query: 313 KGSLEIANMTELTK--KIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLI 370 E + E K K +L+E L + + K+ + + ++ S I Sbjct: 2148 DSEREWLLVLEREKEEKNQLVERLT-SVENEMSSKDVKVNALKQDLDSLQEKLALASSAI 2206 Query: 371 SRKSGRNTASKMKSPWSQLSSETLNQDT-DKKINKNEIAK-LEMVIQSLNKDLVDKEYVI 428 + S + A ++++ S+L E L +K+++ + + + L L++ L K + Sbjct: 2207 RQGSDQLGAKELEASASRLQLEKLLASVQEKELDNSRLQQALGAAQHRLHRLLQKKGFSA 2266 Query: 429 SEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHME------GPSLIHVGTNTEDVNEIAKVQ 482 T+I QL+ Q ++ S+ + E + E + Sbjct: 2267 GAPHQSPPDLSAAAACLHTMITQLEEGQQGQVDTLRSEVNKSVADLERTQEKLEEAERRS 2326 Query: 483 EQLKQE---LNDEIK--DVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKL 537 EQ +QE L E++ + ++ A ++ +L+ ++ + ++ S + Sbjct: 2327 EQKEQEAAGLQTEVELLQSQLHAQVDITNQAAAKLERLSSQLQEKGDQISRM-SVQLQQQ 2385 Query: 538 KQMQKTIDNFSKV-----SDSNKEIV----RLTEELHHLSQKVAE--LEEEKGNLQLHLV 586 +Q Q+ +D + V S +N+E V ++ H S K E LE++ + QL Sbjct: 2386 QQQQQLVDKDAAVAQAMESQANQESVLAQLESLQQEHQRSVKRREQILEQKAKSEQLR-- 2443 Query: 587 DYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLAD 646 +++ES + +K + +T ++ S+LE + Q+ +Q+ + KL Sbjct: 2444 --SEKQLLESALSEKEERLSQAVQTLMEKSSVLEQLQASAAQKDAAFEQERKDWMQKLDQ 2501 Query: 647 ISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDI 706 + + + S S L +++ + K +L ++ L +++ ++ E Sbjct: 2502 LQKELQKESTSPSASAELGKELAQVRLEKTKLERKVQAALLARKEAMKKAEEQERALTQE 2561 Query: 707 MNKLQNYIQENMDLTDKLEKMSAEK--ISELLAKINHEEQSKIQTQFGIDAKIQERDLYI 764 + L+++ ++ DL + S+++ ++ L + ++S + +D Q + + Sbjct: 2562 LTGLRSFEEKVRDLEELRSTCSSDQDELAALRQLLQERDESLRDLKLSLD---QHQSASL 2618 Query: 765 ENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELV 824 N++ EL KS+ L E +A E+ E++A L S L T+ E L Sbjct: 2619 ANLKEELEDLKSQNGHLSEELASKEEALMVGEQRAQALDSKL---------LTVVE-HLE 2668 Query: 825 NRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKAN 884 A L D VEK + + +++ L E+Q L + S +++ E+ + Sbjct: 2669 TAQAELRDKSEQVEKHQEALRAQELTAEQEKGAL--ESQ-LDLLTSALEEERRRCAEQQS 2725 Query: 885 RTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKK 944 R DL+E E T +R L+ L + K ++ + + + ++ Sbjct: 2726 RLDLSEREQAGAATLIRQLKDELGAGGTKLAQFDKVKTCDVCKSGPDDQQGACFSCQQRE 2785 Query: 945 VLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYT 1004 L E ++ E AQL E + + + +++ ++ + H ++ +S Sbjct: 2786 KLQEDLKERQEAFLMSRAQLSEKEELRPAVELQLQQQSRAH------HAWMERAKSE--- 2836 Query: 1005 EQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEM 1064 E+ + + ++ AL +K+ A +S ++ + S L Q +L +E Sbjct: 2837 ---AAELQRSQQHPQDGQSKMAALTRKLQAALLSRKELMKE-NSALKQDAKRLAE-KEHA 2891 Query: 1065 QRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDD 1124 + V L++ EE++ RE + + K +L EM+ +E +S+ + Sbjct: 2892 KEVELSALEAAL--EEVKREKRELETSASKDK-VELRGEMDRLLSENHSLSAACGSLKLT 2948 Query: 1125 ANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLN-- 1182 N+ LK + EE + RS E + + L+ + Q++ + Sbjct: 2949 IENMGQQKEAFSCQLEALKDSQAEELSRWRSQHAELKQQHESLLRSYQSTGAQMDAMRHV 3008 Query: 1183 TELTGHDVVNQ-EQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELW-- 1239 E T D + + ++L+++ + L + L ++ + + ++ + + EL Sbjct: 3009 LEATERDALEAVRKSHRLETERDALEKQARELEGEHDRIKERMHTFSREKQWTVEELERE 3068 Query: 1240 KQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKL 1299 KQ+ +R + ++ +L + E + +++S +E K+ ++ + Sbjct: 3069 KQNSRRRLRELEENHSREASELGHANQQLEAEICRLRASAEELGEKLSELQSEN--KRMA 3126 Query: 1300 QDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSY 1359 Q+ +E L+E+ A+ L+ ++E E + L+ E Q+ Sbjct: 3127 QELQESSCTLEERSAESERSRSSLQLQLE-EALGRMETQTTELGAQVELNNLLQKEKQNL 3185 Query: 1360 KQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQK 1419 Q E + ++ A +++ +N+ + ++LE L ++ E Q+ Sbjct: 3186 SQHMEAMQTELGKKEALIQELQEVVSRHSQETVS-LNE-KVRILEDDKSLLQEELENVQE 3243 Query: 1420 THEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEK---ESELAILRLKMHENANHYETM 1476 T + +E E + L++ +++++LT +S+ L ++ +++ + Sbjct: 3244 TSDKV------KNEKEYLETVLLQNSEKVDELTESVAVLQSQNLELNSQLAASSHTNHRV 3297 Query: 1477 QKESEIERVKLIEELNVKITE-------SVSLNKQVAELNKALEEEVAKTNEMQTALENQ 1529 ++E E E+++L+ EL K+ S ++NK++ EL K +E+ + Q + Q Sbjct: 3298 RQEKEEEQLRLVRELEEKLRAVQRGSQGSKTINKELQELLKEKHQEINQL--QQNCIRYQ 3355 Query: 1530 EIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQ 1566 E+ I+ L + Q V +++K S +Q Sbjct: 3356 EV-ILQLESSSKSSQAAVEQLQRELEKSSEQLSAVRQ 3391 Score = 76.2 bits (179), Expect = 7e-12 Identities = 155/752 (20%), Positives = 300/752 (39%), Gaps = 76/752 (10%) Query: 821 DELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEE-NQNLQISLSDMQQHY-NA 878 DE RL V + ++ QL H+ +K+Q+L+ NQ L+ L+D Q+ ++ Sbjct: 604 DEDEQRLWVSQNELEKLQSQLASARHQQSRDAEKHQLLVTSLNQQLK-GLTDTQESLESS 662 Query: 879 LVEKAN---RT--------DLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIED 927 LVEK RT L E+ S K + QLR+ L + H + I QK E Sbjct: 663 LVEKETALARTCQQLELVSSLQEALSLK-ELQLREASDKLLQAEHSLDS-IWQKCSGSEK 720 Query: 928 LEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLE 987 E ++ + VL EK +K E ++ + ++ N EEL+K+N Sbjct: 721 QCSELKAEVADLTQKLGVLKEKTQKQ-------EVTIESLQREVDQTN---EELDKLNTA 770 Query: 988 LIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYE 1047 +++ Q + EI+ L +L +KD EI AL+ ++ +S++ +E Sbjct: 771 CLEERAQLIHD-----LQGCEREIDSLKDVLLEKDREISALSGHVSEC-TEQLSLLK-HE 823 Query: 1048 SKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIP 1107 KL + L +E + + ++LL ++ R + Q E + +L + Sbjct: 824 LKLKE--QNLIQVENALSKAERELLLLRES--------RSSEQQSLEDRLIQLGDSLKDA 873 Query: 1108 KTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTE 1167 +TE + + + ++ + Q+EE ++ R +Q+Q Sbjct: 874 QTELVKVREHRDSLAAQVGALQEQAH-----------QDEESILELRGEVQKQMRSHGQR 922 Query: 1168 LQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSA 1227 L E I +L +L QE +QL+ +L + + L E R+ + S Sbjct: 923 LSEGEAHI---TSLKDQLVAAAQKLQES-SQLQQQLSKKEESLEKELKASKEERNRLHSQ 978 Query: 1228 VDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIV 1287 ++ E A+ Q L +++ T E++ + QL ++ + + E Sbjct: 979 AEEYRKE-AQTVSQQLEEQKRSQGITRGEMKATAETAAALEAQLREAEKERQRLEAELKT 1037 Query: 1288 TMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIE--DEKVAFXXXXXXXXXXX 1345 + L + LQ K E++ NLQ + ++ + L+ E+E E++ Sbjct: 1038 RDSEKEKLSSDLQSKAENISNLQNLLNSLKSEKQQLQEELEALTEELDLQKEKVRQLSQE 1097 Query: 1346 XXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLEL 1405 D RT Q+ Q + +E L+++ RV+ EA+V E Sbjct: 1098 AASALDSRTSYQNQAQQLSAEAARLQQELDHLQRTLSELGCEAESRRDRVSVLEAQVSEN 1157 Query: 1406 THQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLK 1465 ++ E + +TL ++ E+V Q L +++ E++ LA L+ + Sbjct: 1158 AAVIKALREE------KEELTLQKQELSSEHV-QGLASTAEQLRRSLAERDEALADLQAR 1210 Query: 1466 MHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTA 1525 +Q++ + +L E+ ++ E+ SL +V EE V+K + Sbjct: 1211 ADAQQKELTQLQEQERSLKTQLAEKEHLG-RENQSLKSEVGR----QEEAVSKLQSDAKS 1265 Query: 1526 LENQEIEIVTLNDEITNLQNMVRASSSKIQKH 1557 L+ + ++ ++ N + +R + Q+H Sbjct: 1266 LQEKHSQVC---QQMENREETLRNVKRECQQH 1294 Score = 75.8 bits (178), Expect = 9e-12 Identities = 218/1159 (18%), Positives = 456/1159 (39%), Gaps = 115/1159 (9%) Query: 240 LKDIESKDVRISS-LEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQ 298 L+D++S++ +S L + L SKL +E + K Sbjct: 2625 LEDLKSQNGHLSEELASKEEALMVGEQRAQALDSKLLTVVEHLETAQAELRDKSEQVEKH 2684 Query: 299 SIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKEL-ENKLATMGTESK 357 +E T +EKG+LE + + LT +E E C +Q+ +L E + A T + Sbjct: 2685 QEALRAQELTAEQEKGALE-SQLDLLTSALEE-ERRRCAEQQSRLDLSEREQAGAATLIR 2742 Query: 358 AVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSL 417 + G +++ T KS + +K+ ++ + E + S Sbjct: 2743 QLKDELGAGGTKLAQFDKVKTCDVCKSGPDDQQGACFSCQQREKLQEDLKERQEAFLMS- 2801 Query: 418 NKDLVDKEY----VISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTE 473 L +KE V + + A+LQ Q +G S + T Sbjct: 2802 RAQLSEKEELRPAVELQLQQQSRAHHAWMERAKSEAAELQRSQQHPQDGQSKMAALTRKL 2861 Query: 474 DV-----NEIAKVQEQLKQELNDEIKDVNVKDL-IEKLKSAEEQITQLNDEID-AANKNM 526 E+ K LKQ+ + + K++ + L++A E++ + E++ +A+K+ Sbjct: 2862 QAALLSRKELMKENSALKQDAKRLAEKEHAKEVELSALEAALEEVKREKRELETSASKDK 2921 Query: 527 IKVKS--------NHKLKLK--QMQKTIDNFSKVSDS---NKEIVR--LTEELHHLSQKV 571 ++++ NH L ++ TI+N + ++ E ++ EEL + Sbjct: 2922 VELRGEMDRLLSENHSLSAACGSLKLTIENMGQQKEAFSCQLEALKDSQAEELSRWRSQH 2981 Query: 572 AELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEM-ENLAETRLKAISLLESQKFDLVQEL 630 AEL+++ +L L Y S + D + ++E E A ++ LE+++ L ++ Sbjct: 2982 AELKQQHESL---LRSYQSTGA-QMDAMRHVLEATERDALEAVRKSHRLETERDALEKQA 3037 Query: 631 HILQQKYDEVEDKLADIS--------QLQSDQVCSEIKSVHLEE----QIDALSASKKEL 678 L+ ++D +++++ S +L+ ++ S + LEE + L + ++L Sbjct: 3038 RELEGEHDRIKERMHTFSREKQWTVEELEREKQNSRRRLRELEENHSREASELGHANQQL 3097 Query: 679 ALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNY---IQEN------------MDLTDK 723 I L+ E+L + +L+++ + + +LQ ++E + L + Sbjct: 3098 EAEICRLRASAEELGEKLSELQSENKRMAQELQESSCTLEERSAESERSRSSLQLQLEEA 3157 Query: 724 LEKMSAEKIS-----ELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRI 778 L +M + EL + E+Q+ Q + ++ +++ I+ ++ +S++ Sbjct: 3158 LGRMETQTTELGAQVELNNLLQKEKQNLSQHMEAMQTELGKKEALIQELQEVVSRHSQET 3217 Query: 779 CRLEESIAVMEDRRYSLERKAD--QLGSYLQEKQKAYSEYTIQE-----DELVNRLAVLM 831 L E + ++ED + L+ + + Q S + +K Y E + + DEL +AVL Sbjct: 3218 VSLNEKVRILEDDKSLLQEELENVQETSDKVKNEKEYLETVLLQNSEKVDELTESVAVLQ 3277 Query: 832 DHDRVVEKQLLEIEHENKEL-QKKNQILLEENQNLQISLSDMQ-----------QHYNAL 879 + + QL H N + Q+K + L + L+ L +Q + L Sbjct: 3278 SQNLELNSQLAASSHTNHRVRQEKEEEQLRLVRELEEKLRAVQRGSQGSKTINKELQELL 3337 Query: 880 VEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESA 939 EK + + +YQ + LES+ K Q + Q ++E+E + + + Sbjct: 3338 KEKHQEINQLQQNCIRYQEVILQLESSSK----SSQAAVEQLQRELEKSSEQLSAVRQKC 3393 Query: 940 IRDKKVLNEKYEKNIEYVTQ-----LEAQLQEYKNNIENLNMNVE-ELNKMNLELIDKH- 992 R + L+E ++N+ Q E+Q ++ + + + E E DK Sbjct: 3394 SRAEAELSE--QRNLLQQAQQKRPGAESQRDPTALDLSHPSRSSEGHRESQPAEKADKEA 3451 Query: 993 -VQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLA 1051 +Q+Q Q +Q ++ +L L D E+ AL + +++ +S +S + Sbjct: 3452 VLQQQMAQLVLSKDQESKKVQELKQQLDSGDVELKALEGALRSSEAK-LSALSARPAG-P 3509 Query: 1052 QFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEG 1111 + ++ + ++ QLL+ + +R ++ ++ EL+ T L + I + Sbjct: 3510 EASSLWTQVHQQAGSEDHQLLEPGSVIKRSLQNIRVKEKEMDELRLTHLKLQRTIDQYSV 3569 Query: 1112 MIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQ-ERSVLQEQSAKLNTELQE 1170 + + ANN D ++ + + ++ E+ +L+ Q + + E Sbjct: 3570 AAAAQQRQLFVLSANNADVCERAELMGAQVTELSAQVDRLEKEKDLLRRQLS--DREDAV 3627 Query: 1171 CYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQ 1230 C T QL+ + E++ L + L+ L D +S++ + + S Q Sbjct: 3628 CQT---QLQLQQAQKRRCLQAASERLEGLAAHLKTLLQSKDAEISSLLSCKDAQMSGYLQ 3684 Query: 1231 RGFEIAELWKQHLAQREADFQKTEHELRV---QLSAFESKYEQLLDSVQSSTQEETNKIV 1287 ++ + A EA H+ QL ++K L V +S+QE Sbjct: 3685 ---QLQANGRSQAAAYEARLAALGHQREAAAGQLRGLQAKVRHLQVQVDTSSQESQQAAA 3741 Query: 1288 TMEQVTSLQNKLQDKEEHL 1306 M+ LQ + E L Sbjct: 3742 KMDAFRKSMAALQSERERL 3760 Score = 66.5 bits (155), Expect = 6e-09 Identities = 205/1148 (17%), Positives = 466/1148 (40%), Gaps = 126/1148 (10%) Query: 212 EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLE---EANK--LLEAARFE 266 E K + + + AE K + + LL+ +S ++ ++ EA + LEA R Sbjct: 2964 EALKDSQAEELSRWRSQHAELKQQHESLLRSYQSTGAQMDAMRHVLEATERDALEAVRKS 3023 Query: 267 ISLEHS-----KLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKT-------EIEEKG 314 LE K A+ELE + ++E EK E+EE Sbjct: 3024 HRLETERDALEKQARELEGEHDRIKERMHTFSREKQWTVEELEREKQNSRRRLRELEENH 3083 Query: 315 SLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKS 374 S E + EL + LE C++R + +EL KL+ + +E+K ++ ++ S + +S Sbjct: 3084 SREAS---ELGHANQQLEAEICRLRASAEELGEKLSELQSENKRMAQELQESSCTLEERS 3140 Query: 375 GRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTX 434 S+ S +L ++ + + E E+ Q +L+ KE Sbjct: 3141 AE----------SERSRSSLQLQLEEALGRMETQTTELGAQVELNNLLQKEK--QNLSQH 3188 Query: 435 XXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIK 494 K+ LI +LQ +H + T +NE ++ E K L +E++ Sbjct: 3189 MEAMQTELGKKEALIQELQEVVSRHSQ---------ETVSLNEKVRILEDDKSLLQEELE 3239 Query: 495 DVNVKDLIEKLKSAEEQ----ITQLNDEIDAANKNMIKVKS-NHKLKLKQMQKTIDNFSK 549 NV++ +K+K+ +E + Q ++++D +++ ++S N +L + + N Sbjct: 3240 --NVQETSDKVKNEKEYLETVLLQNSEKVDELTESVAVLQSQNLELNSQLAASSHTNHRV 3297 Query: 550 VSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLA 609 + +E +RL EL + V ++G+ ++ + +++ + ++++ +++ Sbjct: 3298 RQEKEEEQLRLVRELEEKLRAV-----QRGSQGSKTINKELQELLK-EKHQEINQLQQNC 3351 Query: 610 ETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQID 669 + I LES + LQ++ ++ ++L+ + Q CS ++ L EQ + Sbjct: 3352 IRYQEVILQLESSSKSSQAAVEQLQRELEKSSEQLSAVR-----QKCSRAEA-ELSEQRN 3405 Query: 670 ALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSA 729 L ++++ + Q T DL + ++ E D L++ A Sbjct: 3406 LLQQAQQKRPGA-------ESQRDPTALDLSHPSRSSEGHRESQPAEKADKEAVLQQQMA 3458 Query: 730 EKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVME 789 + + ++ +++SK K+QE +++ + EL + + E ++ + Sbjct: 3459 QLV------LSKDQESK---------KVQELKQQLDSGDVELKALEGALRSSEAKLSALS 3503 Query: 790 DRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENK 849 R E A L + + ++ + ++ ++ R + + RV EK++ E+ + Sbjct: 3504 ARPAGPE--ASSLWTQVHQQAGSEDHQLLEPGSVIKR---SLQNIRVKEKEMDELRLTHL 3558 Query: 850 ELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKR 909 +LQ+ Q S++ Q V AN D+ E + Q+ +L + + R Sbjct: 3559 KLQRTID---------QYSVAAAAQQRQLFVLSANNADVCE-RAELMGAQVTELSAQVDR 3608 Query: 910 ITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKN 969 + E + L+ ++ + ED + Q++ A + ++ L E+ LE K Sbjct: 3609 LEKE-KDLLRRQLSDREDAVCQTQLQLQQA-QKRRCLQAASER-------LEGLAAHLKT 3659 Query: 970 NIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALN 1029 +++ + + L + ++Q+ Q Y + L + ++ L Sbjct: 3660 LLQSKDAEISSLLSCKDAQMSGYLQQLQANGRSQAAAYEARLAALGHQREAAAGQLRGLQ 3719 Query: 1030 QKINNAQVSYMSMVSDYE---SKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVR 1086 K+ + QV + + + +K+ F + ++ E +R+ + + N ++ +R Sbjct: 3720 AKVRHLQVQVDTSSQESQQAAAKMDAFRKSMAALQSERERLVSRCRTLETEN---RLGLR 3776 Query: 1087 EQDDQ---IKELKE--TKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXX 1141 D + K LK+ KL +M+ +E ++ + + +D N V Sbjct: 3777 GPDGEGGASKGLKQEIRKLLNQMDDLNSENAMLRAQLVRYREDLNQVLSLKDDQLKLLLQ 3836 Query: 1142 LKVQEEEEFIQERSVLQEQ--SAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQL 1199 + Q+++ +EQ A+L + +E ++ ++ + L E + +E++ Sbjct: 3837 KQQDAIRNLEQQKAAAEEQQREARLQVQQKEEESEALRAQ-LARERAQEEEEEEEEVAGG 3895 Query: 1200 KSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRV 1259 ++L +L E + + AELR I + +G + LA+ + + E Sbjct: 3896 AAQLRRLQQELLSQRTLTAELRQHIQLLEEDQGRTSTLVEAARLAEDQPQLPQKLSESES 3955 Query: 1260 QLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQ 1319 Q + + E L ++ ++ Q++ ++++ E +L+N ++ LR + ++ V Sbjct: 3956 QGRSARLQNEALRKAM-AALQDDRDRLI--EDFKTLRN---GYDQELRESRAAFSRVERS 4009 Query: 1320 IEILRSEI 1327 ++ S++ Sbjct: 4010 LQEASSDL 4017 Score = 36.3 bits (80), Expect = 7.0 Identities = 61/341 (17%), Positives = 136/341 (39%), Gaps = 11/341 (3%) Query: 505 LKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNF-SKVSDSNKEIVRLTEE 563 L+S E++ ++ N+ ++ K +++ I +++ D N E L + Sbjct: 3753 LQSERERLVSRCRTLETENRLGLRGPDGEGGASKGLKQEIRKLLNQMDDLNSENAMLRAQ 3812 Query: 564 LHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQK 623 L + + ++ K + QL L+ I + +K E E RL+ E + Sbjct: 3813 LVRYREDLNQVLSLKDD-QLKLLLQKQQDAIRNLEQQKAAAEEQQREARLQVQQKEEESE 3871 Query: 624 FDLVQELHILQQKYDEVEDKLA----DISQLQSDQVCSEIKSVHLEEQIDALSASKKELA 679 Q Q+ +E E+++A + +LQ + + + L + I L + + Sbjct: 3872 ALRAQLARERAQEEEEEEEEVAGGAAQLRRLQQELLSQRTLTAELRQHIQLLEEDQGRTS 3931 Query: 680 LVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKI 739 ++E +L ++Q K E++ + +LQN E + + +++ E + Sbjct: 3932 TLVEAARLAEDQPQLPQKLSESESQGRSARLQN---EALRKAMAALQDDRDRLIEDFKTL 3988 Query: 740 NHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKA 799 + +++ +++ ER L + + + + + L+ S L Sbjct: 3989 RNGYDQELRESRAAFSRV-ERSLQEASSDLAVLAKQRDVLLLQMSALKSSQTHAELSGLV 4047 Query: 800 DQLGSYLQEKQKAYSEYTIQEDELVNRLAVLM-DHDRVVEK 839 DQL L EK++ S ++ Q D + L + DR++E+ Sbjct: 4048 DQLSGALAEKERELSSHSRQLDAFSRSMGSLQNERDRLMEE 4088 >UniRef50_A2ERV4 Cluster: Putative uncharacterized protein; n=1; Trichomonas vaginalis G3|Rep: Putative uncharacterized protein - Trichomonas vaginalis G3 Length = 1095 Score = 135 bits (327), Expect = 8e-30 Identities = 204/1058 (19%), Positives = 468/1058 (44%), Gaps = 99/1058 (9%) Query: 507 SAEEQITQLNDEIDAAN---KNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEE 563 +A + +T+ N+ I+ N ++ ++ +S + +Q +K +K+ + N + Sbjct: 60 AANKTVTEQNNRIEKLNSEIQHFVEKESKYVQIGEQAKKFAAERNKLMEENNLFRQANNN 119 Query: 564 LHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKA-ISLLESQ 622 ++ + + A+L EE LQ + + E+D +K ++N A L + L++ + Sbjct: 120 VNEVVESAAKLREENKELQSKVNELQK----ENDDFKSKT-LQNQASALLGGFMGLVKGE 174 Query: 623 KFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVI 682 QE+ L+++++E E LA IS +++Q+ +++ + E+ + E +I Sbjct: 175 S----QEVTELRKRHNEREAILAKIST-ENNQLKEKLQKLEAEKN------NNSEYEQII 223 Query: 683 ENLKLDKEQLYGTIKDLENDKEDIMNK--------LQNYIQENMDLTDKLEKMSAEKIS- 733 E + + E L +++ N ++ + K +++ +N L+D+LEK+ +EK Sbjct: 224 EEITKENENLKSKLQNQNNSSDETLRKQLLEKDSTIKSLSDDNKSLSDELEKLDSEKEQK 283 Query: 734 --ELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDR 791 E +AKIN + S KI E +L + + + L + K + +E + Sbjct: 284 EKEFIAKINELQNSLSNLNDKNKNKISELELQNQALNNSLIELKHNNETILMEKQQIETQ 343 Query: 792 RYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKEL 851 +L K +L + LQ+ Q+ + + Q+ ++++ L ++ + K L E+ +EN L Sbjct: 344 ISNLISKNSELETKLQKMQQMNAG-SEQDRDIISDLQKSLESSNIKAKNL-ELTNEN--L 399 Query: 852 QKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRIT 911 QK+ L E L ++ + Q +E N+ + + + K L++ + ++++ Sbjct: 400 QKEGNSLKLEISKLNSNIEKLNQEK---IENNNKINELQLNNEKSLENLQNHQKIIEKLN 456 Query: 912 HEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNI 971 E + I +K +++ + + I++ + + LN++ +N + + +L ++ K NI Sbjct: 457 QE-KIEITKKINDLQSVNDKSKENIQNYEKIIEKLNQEKIENTKKIDELNDVNEKSKENI 515 Query: 972 ENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQK 1031 +N +E+LN LE + ++++ ++ E+ N ++ L ++ D+ + Q Sbjct: 516 QNNQKIIEKLNSKFLEF-ENQMKEKDSEIAKLQEENSNFVSNLQKSKEESDKNLTEKIQN 574 Query: 1032 INNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQ 1091 + N + + ++D + + T K +N+ E ++ Q Q+ E+ L ++ Sbjct: 575 LINDRTKLNNTLNDLSKENKEITEKYQNLSSENEKTKSQ----NQNLEKNLDLATKELST 630 Query: 1092 IKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFI 1151 IKE + +L + +TE ++ + ++ N+ L + +E E I Sbjct: 631 IKE-QNKELVKQNQDMQTE---LNDLKKFKQENLTNLQNY----------LNLMKESETI 676 Query: 1152 Q-ERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTEN 1210 + E L+ TELQ + + L+ + L +E + KL+Q N N Sbjct: 677 KTENKSLKTNLENATTELQTTKSNLQNLQKQSQNLEKRANSAEETAENVLQKLKQQNEIN 736 Query: 1211 DNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQ 1270 +NL + L+ + + +R + E + Q+ + +K E + Q+ E+KY+ Sbjct: 737 NNLELNLQTLKQE--NEIQKRKIDEKEKILLQIQQQNEENEKKNSENKKQM---ETKYDI 791 Query: 1271 LLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDE 1330 +++ ++ E ++I K + KE NLQ+ + +N +I ++E+E Sbjct: 792 MINDLKQEINELNDQI-----------KSKSKELDEINLQKVTENNMNHEKI--EKLENE 838 Query: 1331 KVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXX 1390 + +LR + + + S +N EN + K Sbjct: 839 NKMYSDRCSDLESQLQSMISELR-----HLKSERDSTPVLNSEN--VNKIIEGLREENKD 891 Query: 1391 XXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIED 1450 +++++ + L + D EI + + L+ +N++ ++Q++ E+ ++ + Sbjct: 892 LSEKLSESLDRENNLLNDATNHDMEITK----LKVDLSNKNNQIIELKQKVTEFSTKVTN 947 Query: 1451 LTYEKESELAILRLKMHENANHYETMQKESEIERVKL--IEELNVKITESV-SLNKQVAE 1507 +E+ SE K+ E + YE ++ E+EI KL ++++ ++++V L + + + Sbjct: 948 --FEEISE------KLKEKEHDYERIKNENEIANGKLQSLDKIRGDLSKTVDELRENLQK 999 Query: 1508 LNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQN 1545 N +L + + + A E IV L I +++ Sbjct: 1000 TNLSLSKTQDELKQKNGAYEEAVKRIVKLMKYIKKIES 1037 Score = 128 bits (310), Expect = 9e-28 Identities = 181/942 (19%), Positives = 411/942 (43%), Gaps = 63/942 (6%) Query: 638 DEVEDKLADISQLQS--DQVCSEIKSVH--LEEQIDALSASKKELALVIENLKLDKEQLY 693 +++E+K IS LQS D +E + + + EQ + + E+ +E + Q+ Sbjct: 35 NDIEEKKTKISMLQSIIDTTTNERDAANKTVTEQNNRIEKLNSEIQHFVEK-ESKYVQIG 93 Query: 694 GTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSA--EKISELLAKINHEEQS----KI 747 K ++ +M + + Q N ++ + +E + E+ EL +K+N ++ K Sbjct: 94 EQAKKFAAERNKLMEENNLFRQANNNVNEVVESAAKLREENKELQSKVNELQKENDDFKS 153 Query: 748 QT-QFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYL 806 +T Q A + ++ E+++ + R E +A + L+ K +L + Sbjct: 154 KTLQNQASALLGGFMGLVKGESQEVTELRKRHNEREAILAKISTENNQLKEKLQKLEAEK 213 Query: 807 Q---EKQKAYSEYTIQEDELVNRLAVLMDH-DRVVEKQLLEIEHENKELQKKNQILLEEN 862 E ++ E T + + L ++L + D + KQLLE + K L N+ L +E Sbjct: 214 NNNSEYEQIIEEITKENENLKSKLQNQNNSSDETLRKQLLEKDSTIKSLSDDNKSLSDEL 273 Query: 863 QNLQISLSDMQQHYNALVEK-----ANRTDLAESESTKYQTQLRDLESNLKRITHEHQTL 917 + L ++ + A + + +N D +++ ++ + Q + L ++L + H ++T+ Sbjct: 274 EKLDSEKEQKEKEFIAKINELQNSLSNLNDKNKNKISELELQNQALNNSLIELKHNNETI 333 Query: 918 IVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMN 977 +++K+ QIE+ I + N + E ++ + Q+ A ++ ++ I +L + Sbjct: 334 LMEKQ------------QIETQISNLISKNSELETKLQKMQQMNAGSEQDRDIISDLQKS 381 Query: 978 VEELN--KMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNA 1035 +E N NLEL ++++QK+ EI+KLN+ +++ ++E I N KIN Sbjct: 382 LESSNIKAKNLELTNENLQKEGNSLK-------LEISKLNSNIEKLNQEKIENNNKINEL 434 Query: 1036 QVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKEL 1095 Q++ + + L +E + +E ++K++ D + N++ + ++ + I++L Sbjct: 435 QLNNEKSLEN----LQNHQKIIEKLNQEKIEITKKINDLQSVNDKSKENIQNYEKIIEKL 490 Query: 1096 KETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEE--EFIQE 1153 + K+ I + + S E + ++ ++ +K ++ E + +E Sbjct: 491 NQEKIENTKKIDELNDVNEKSK-ENIQNNQKIIEKLNSKFLEFENQMKEKDSEIAKLQEE 549 Query: 1154 RSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQ--EQINQLKSKLEQLNTEND 1211 S K E + T+ IQ +N ++ +N ++ ++ K + L++EN+ Sbjct: 550 NSNFVSNLQKSKEESDKNLTEKIQ-NLINDRTKLNNTLNDLSKENKEITEKYQNLSSENE 608 Query: 1212 NLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQL 1271 S L ++ A + I E K+ L ++ D Q ++L+ + + Sbjct: 609 KTKSQNQNLEKNLDLATKELS-TIKEQNKE-LVKQNQDMQTELNDLKKFKQENLTNLQNY 666 Query: 1272 LDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEK 1331 L+ ++ S +T + + +LQ + +L+NLQ++ ++ + E + Sbjct: 667 LNLMKESETIKTENKSLKTNLENATTELQTTKSNLQNLQKQSQNLEKRANSAE-ETAENV 725 Query: 1332 VAFXXXXXXXXXXXXXXXXDLRTENQSYKQM---QEQSILNINEENAQL-KKSSXXXXXX 1387 + L+ EN+ K+ +E+ +L I ++N + KK+S Sbjct: 726 LQKLKQQNEINNNLELNLQTLKQENEIQKRKIDEKEKILLQIQQQNEENEKKNSENKKQM 785 Query: 1388 XXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKR 1447 +ND + ++ EL Q++ K E+ + + +++ E + + Y R Sbjct: 786 ETKYDIMINDLKQEINELNDQIKSKSKELDEINLQKVTENNMNHEKIEKLENENKMYSDR 845 Query: 1448 IEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITE--SVSLNKQV 1505 DL + +S ++ LR + + + E+ + ++ + E N ++E S SL+++ Sbjct: 846 CSDLESQLQSMISELR-HLKSERDSTPVLNSENVNKIIEGLREENKDLSEKLSESLDREN 904 Query: 1506 AELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMV 1547 LN A ++ T +++ L N+ +I+ L ++T V Sbjct: 905 NLLNDATNHDMEIT-KLKVDLSNKNNQIIELKQKVTEFSTKV 945 Score = 125 bits (301), Expect = 1e-26 Identities = 185/1010 (18%), Positives = 425/1010 (42%), Gaps = 72/1010 (7%) Query: 406 EIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPS- 464 EI KL+ I+ + + +I ++ I +L E Q +E S Sbjct: 29 EIGKLKNDIEEKKTKISMLQSIIDTTTNERDAANKTVTEQNNRIEKLNSEIQHFVEKESK 88 Query: 465 LIHVGTNTEDVNEIAKVQEQLKQELN-DEIKDVNVKDLIEKLKSAEEQITQLNDEIDAAN 523 + +G E + A + +L +E N + NV +++E E+ +L +++ Sbjct: 89 YVQIG---EQAKKFAAERNKLMEENNLFRQANNNVNEVVESAAKLREENKELQSKVNELQ 145 Query: 524 KNMIKVKSNHKLKLKQMQKTIDNF-SKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQ 582 K KS K Q + F V ++E+ L + + +A++ E L+ Sbjct: 146 KENDDFKS--KTLQNQASALLGGFMGLVKGESQEVTELRKRHNEREAILAKISTENNQLK 203 Query: 583 LHLVDYDSGRMIESDVYKKMIEM-----ENL-AETRLKAISLLESQKFDLVQELHILQQK 636 L ++ + S+ Y+++IE ENL ++ + + S E+ + L+++ ++ Sbjct: 204 EKLQKLEAEKNNNSE-YEQIIEEITKENENLKSKLQNQNNSSDETLRKQLLEKDSTIKSL 262 Query: 637 YDEVEDKLADISQLQSDQVCSEIKSV-HLEEQIDALSASKKELALVIENLKLDKEQLYGT 695 D+ + ++ +L S++ E + + + E ++LS + I L+L + L + Sbjct: 263 SDDNKSLSDELEKLDSEKEQKEKEFIAKINELQNSLSNLNDKNKNKISELELQNQALNNS 322 Query: 696 IKDLENDKEDIM-------NKLQNYIQENMDLTDKLEKMSAEKI-SELLAKINHEEQSKI 747 + +L+++ E I+ ++ N I +N +L KL+KM SE I + Q + Sbjct: 323 LIELKHNNETILMEKQQIETQISNLISKNSELETKLQKMQQMNAGSEQDRDIISDLQKSL 382 Query: 748 QTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLG---- 803 ++ + K + +L EN++ E + K I +L +I + + K ++L Sbjct: 383 ESS---NIKAKNLELTNENLQKEGNSLKLEISKLNSNIEKLNQEKIENNNKINELQLNNE 439 Query: 804 ---SYLQEKQKAYSEYTIQEDELVNRLAVLM-----------DHDRVVEKQLLEIEHENK 849 LQ QK + ++ E+ ++ L ++++++EK E K Sbjct: 440 KSLENLQNHQKIIEKLNQEKIEITKKINDLQSVNDKSKENIQNYEKIIEKLNQEKIENTK 499 Query: 850 ELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKR 909 ++ + N + + +N+Q + +++ + +E N+ +SE K Q + + SNL++ Sbjct: 500 KIDELNDVNEKSKENIQNNQKIIEKLNSKFLEFENQMKEKDSEIAKLQEENSNFVSNLQK 559 Query: 910 ITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKN 969 E + +K + + + + N + ++ K + EKY+ + ++Q Q + Sbjct: 560 SKEESDKNLTEKIQNLINDRTKLNNTLNDLSKENKEITEKYQNLSSENEKTKSQNQNLEK 619 Query: 970 NIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTE-QYINEINKLNALLKQKDEEIIAL 1028 N++ + + + N EL+ K Q QT+ D + + N N N L K+ E I Sbjct: 620 NLDLATKELSTIKEQNKELV-KQNQDMQTELNDLKKFKQENLTNLQNYLNLMKESETIKT 678 Query: 1029 NQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQ 1088 K S + + + ++L + L+N++++ Q + K+ +++ E + +++Q Sbjct: 679 ENK------SLKTNLENATTELQTTKSNLQNLQKQSQNLEKRANSAEETAENVLQKLKQQ 732 Query: 1089 DD-------QIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXX 1141 ++ ++ LK+ + I + E +++ + ++ N + Sbjct: 733 NEINNNLELNLQTLKQENEIQKRKIDEKEKILLQIQQQNEENEKKNSENKKQMETKYDIM 792 Query: 1142 L-----KVQEEEEFIQERS-VLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQ 1195 + ++ E + I+ +S L E + + TE + KI +LE N + + Q Sbjct: 793 INDLKQEINELNDQIKSKSKELDEINLQKVTENNMNHEKIEKLENENKMYSDRCSDLESQ 852 Query: 1196 INQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADF--QKT 1253 + + S+L L +E D+ +E + I + + +++E + L RE + T Sbjct: 853 LQSMISELRHLKSERDSTPVLNSENVNKIIEGLREENKDLSEKLSESL-DRENNLLNDAT 911 Query: 1254 EHELRV-QLSA-FESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQE 1311 H++ + +L +K Q+++ Q T+ T K+ E+++ + + E ++N E Sbjct: 912 NHDMEITKLKVDLSNKNNQIIELKQKVTEFST-KVTNFEEISEKLKEKEHDYERIKNENE 970 Query: 1312 KYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQ 1361 + ++ +R ++ +L+ +N +Y++ Sbjct: 971 IANGKLQSLDKIRGDLSKTVDELRENLQKTNLSLSKTQDELKQKNGAYEE 1020 Score = 109 bits (261), Expect = 8e-22 Identities = 176/874 (20%), Positives = 363/874 (41%), Gaps = 54/874 (6%) Query: 723 KLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLE 782 K + AE I +L I ++ Q ID ERD + + + +RI +L Sbjct: 22 KCNNLEAE-IGKLKNDIEEKKTKISMLQSIIDTTTNERDAANKTVTEQ----NNRIEKLN 76 Query: 783 ESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLL 842 I ++ E K Q+G Q K+ A + E+ + R A + + VVE Sbjct: 77 SEIQHFVEK----ESKYVQIGE--QAKKFAAERNKLMEENNLFRQAN-NNVNEVVESAA- 128 Query: 843 EIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAES-ESTKYQTQLR 901 ++ ENKELQ K L +EN + + +Q +AL+ ES E T+ + + Sbjct: 129 KLREENKELQSKVNELQKENDDFKSKT--LQNQASALLGGFMGLVKGESQEVTELRKRHN 186 Query: 902 DLESNLKRITHEHQTLI--VQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYE-KNIEYVT 958 + E+ L +I+ E+ L +QK + ++ E+ IE ++ + L K + +N Sbjct: 187 EREAILAKISTENNQLKEKLQKLEAEKNNNSEYEQIIEEITKENENLKSKLQNQNNSSDE 246 Query: 959 QLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALL 1018 L QL E + I++L+ + + L+ LE +D ++++ + + N ++ LN Sbjct: 247 TLRKQLLEKDSTIKSLSDDNKSLSD-ELEKLDSEKEQKEKEFIAKINELQNSLSNLNDKN 305 Query: 1019 KQKDEEIIALNQKINNAQV-------SYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQL 1071 K K E+ NQ +NN+ + + + E++++ +K +E ++Q++ + Sbjct: 306 KNKISELELQNQALNNSLIELKHNNETILMEKQQIETQISNLISKNSELETKLQKMQQMN 365 Query: 1072 LDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXX 1131 S+Q + + L + + + K +LT E N+ K EG + I ++ + ++ Sbjct: 366 AGSEQDRDIISDLQKSLESSNIKAKNLELTNE-NLQK-EGNSLKLEISKLNSNIEKLNQE 423 Query: 1132 XXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVV 1191 L++ E+ ++ Q+ KLN E E KI L+++N + + ++ Sbjct: 424 KIENNNKINELQLNNEKS-LENLQNHQKIIEKLNQEKIEITKKINDLQSVNDK-SKENIQ 481 Query: 1192 NQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQ 1251 N E+I + KL Q EN + + ++ + Q +I E + E + Sbjct: 482 NYEKIIE---KLNQEKIENTKKIDELNDVNEKSKENI-QNNQKIIEKLNSKFLEFENQMK 537 Query: 1252 KTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTM-EQVTSLQNKLQDKEEHLRNLQ 1310 + + E+ + L S + S + T KI + T L N L D + + + Sbjct: 538 EKDSEIAKLQEENSNFVSNLQKSKEESDKNLTEKIQNLINDRTKLNNTLNDLSKENKEIT 597 Query: 1311 EKYADVINQIEILRSEIED-EK-----VAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQE 1364 EKY ++ ++ E +S+ ++ EK D++TE K+ ++ Sbjct: 598 EKYQNLSSENEKTKSQNQNLEKNLDLATKELSTIKEQNKELVKQNQDMQTELNDLKKFKQ 657 Query: 1365 QSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYT 1424 +++ N+ + L K S + +A T +L+ S + Q + + Sbjct: 658 ENLTNL-QNYLNLMKESETIKTENKSLKTNLENA-------TTELQTTKSNL-QNLQKQS 708 Query: 1425 ITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIER 1484 L +R + E + +++ K+ ++ EL + LK + +KE + + Sbjct: 709 QNLEKRANSAEETAENVLQKLKQQNEIN--NNLELNLQTLKQENEIQKRKIDEKEKILLQ 766 Query: 1485 VKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQ 1544 ++ E N K S + + + + + + + NE+ ++++ E+ +N + Sbjct: 767 IQQQNEENEK-KNSENKKQMETKYDIMINDLKQEINELNDQIKSKSKELDEINLQKVTEN 825 Query: 1545 NMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNK 1578 NM K++ SD + QL + +++ Sbjct: 826 NMNHEKIEKLENENKMYSDRCSDLESQLQSMISE 859 Score = 92.3 bits (219), Expect = 1e-16 Identities = 170/774 (21%), Positives = 324/774 (41%), Gaps = 53/774 (6%) Query: 151 IKEKDNALSVLQVKMKIMETTILDLQEKINEKDQI-IEAKNKATTXXXXXXXXXXXXXXX 209 I E N+LS L K K + + L+LQ + I ++ N+ Sbjct: 291 INELQNSLSNLNDKNK-NKISELELQNQALNNSLIELKHNNETILMEKQQIETQISNLIS 349 Query: 210 XXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISL 269 + + ++ KMQ+ E + +D L K +ES +++ +LE N+ L+ + L Sbjct: 350 KNSELETKLQKMQQMNAGSEQD-RDIISDLQKSLESSNIKAKNLELTNENLQKEGNSLKL 408 Query: 270 EHSKLAQELEQXXXXXXXXXXXXXXLA---KQSIEPSCEEKTEIEEKGSLEIANMTELTK 326 E SKL +E+ L ++S+E + + +I EK + E E+TK Sbjct: 409 EISKLNSNIEKLNQEKIENNNKINELQLNNEKSLE-NLQNHQKIIEKLNQE---KIEITK 464 Query: 327 KIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPW 386 KI L+ +N + ++ + E + + E K ++ ++ KS N + K Sbjct: 465 KINDLQSVNDKSKENIQNYEKIIEKLNQE-KIENTKKIDELNDVNEKSKENIQNNQKI-I 522 Query: 387 SQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKD 446 +L+S+ L + K +EIAKL Q N + V E+ D Sbjct: 523 EKLNSKFLEFENQMKEKDSEIAKL----QEENSNFVSNLQKSKEESDKNLTEKIQNLIND 578 Query: 447 TLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQ-LKQELNDEIKDVN-VKDLIEK 504 L + E + N NE K Q Q L++ L+ K+++ +K+ ++ Sbjct: 579 RTKLNNTL-NDLSKENKEITEKYQNLSSENEKTKSQNQNLEKNLDLATKELSTIKEQNKE 637 Query: 505 L-KSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEE 563 L K ++ T+LND +N+ ++ + L L + +TI +K +N E T E Sbjct: 638 LVKQNQDMQTELNDLKKFKQENLTNLQ--NYLNLMKESETIKTENKSLKTNLE--NATTE 693 Query: 564 LHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQK 623 L + L+++ NL+ +S +V +K+ + + LE Sbjct: 694 LQTTKSNLQNLQKQSQNLEKRA---NSAEETAENVLQKLKQQNEINNN-------LELNL 743 Query: 624 FDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIE 683 L QE I ++K DE E L I Q Q+++ +E K+ ++Q++ + ++I Sbjct: 744 QTLKQENEIQKRKIDEKEKILLQIQQ-QNEE--NEKKNSENKKQMET------KYDIMIN 794 Query: 684 NLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEK--ISELLAKINH 741 +LK + +L IK + ++I LQ + NM+ +K+EK+ E S+ + + Sbjct: 795 DLKQEINELNDQIKSKSKELDEI--NLQKVTENNMN-HEKIEKLENENKMYSDRCSDLES 851 Query: 742 EEQSKIQTQFGIDAKIQERD-LYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKA- 799 + QS I + ++ L EN+ + + L E ++ DR +L A Sbjct: 852 QLQSMISELRHLKSERDSTPVLNSENVNKIIEGLREENKDLSEKLSESLDRENNLLNDAT 911 Query: 800 --DQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQI 857 D + L+ + I+ + V + + + + ++L E EH+ + ++ +N+I Sbjct: 912 NHDMEITKLKVDLSNKNNQIIELKQKVTEFSTKVTNFEEISEKLKEKEHDYERIKNENEI 971 Query: 858 LLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRD-LESNLKRI 910 + Q+L D+ + + L E +T+L+ S++ Q E +KRI Sbjct: 972 ANGKLQSLDKIRGDLSKTVDELRENLQKTNLSLSKTQDELKQKNGAYEEAVKRI 1025 Score = 85.8 bits (203), Expect = 9e-15 Identities = 136/721 (18%), Positives = 303/721 (42%), Gaps = 59/721 (8%) Query: 897 QTQLRDLESNLKRITHEHQTL---IVQKKKEIEDLEIEFNTQIESAIRDKKVLNE--KYE 951 +T++ L+S + T+E + ++ IE L E +E + ++ + K+ Sbjct: 41 KTKISMLQSIIDTTTNERDAANKTVTEQNNRIEKLNSEIQHFVEKESKYVQIGEQAKKFA 100 Query: 952 KNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEI 1011 + + ++ NN+ + + +L + N EL K V + Q ++ D+ + + Sbjct: 101 AERNKLMEENNLFRQANNNVNEVVESAAKLREENKELQSK-VNELQKENDDFKSKTLQ-- 157 Query: 1012 NKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQL 1071 N+ +ALL + +Q++ + + ++ E+ LA+ +T+ ++E++Q++ + Sbjct: 158 NQASALLGGFMGLVKGESQEVTELRKRH----NEREAILAKISTENNQLKEKLQKLEAEK 213 Query: 1072 LDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXX 1131 ++ ++ + ++ + +E ++ +L+ + + + K + + STI+ +SDD ++ Sbjct: 214 NNNSEYEQIIEEITKENENLKSKLQNQNNSSDETLRK-QLLEKDSTIKSLSDDNKSLSDE 272 Query: 1132 XXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKI-IQLETLNTELTG--H 1188 K Q+E+EFI + + LQ + LN + + +++ +Q + LN L H Sbjct: 273 LEKLDSE----KEQKEKEFIAKINELQNSLSNLNDKNKNKISELELQNQALNNSLIELKH 328 Query: 1189 D----VVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVD-----QRGFEIAELW 1239 + ++ ++QI S L N+E + L + ++ + D Q+ E + + Sbjct: 329 NNETILMEKQQIETQISNLISKNSELETKLQKMQQMNAGSEQDRDIISDLQKSLESSNIK 388 Query: 1240 KQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKI--VTMEQVTSLQN 1297 ++L + QK + L++++S S E+L E NKI + + SL+N Sbjct: 389 AKNLELTNENLQKEGNSLKLEISKLNSNIEKL----NQEKIENNNKINELQLNNEKSLEN 444 Query: 1298 KLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKV------AFXXXXXXXXXXXXXXXXD 1351 LQ+ ++ + L ++ ++ +I L+S + K + Sbjct: 445 -LQNHQKIIEKLNQEKIEITKKINDLQSVNDKSKENIQNYEKIIEKLNQEKIENTKKIDE 503 Query: 1352 LRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLEL 1411 L N+ K+ + + I + N++ + + V L E Sbjct: 504 LNDVNEKSKENIQNNQKIIEKLNSKFLEFENQMKEKDSEIAKLQEENSNFVSNLQKSKEE 563 Query: 1412 KDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKE---SELAILRLKMHE 1468 D + +K T+ N+ ++ ++ E ++ ++L+ E E S+ L + Sbjct: 564 SDKNLTEKIQNLINDRTKLNNTLNDLSKENKEITEKYQNLSSENEKTKSQNQNLEKNLDL 623 Query: 1469 NANHYETMQKESEIERVKLIEELNVKITE-----SVSLNKQVAELNKALEEEVAKTNE-- 1521 T+ KE E VK +++ ++ + +L LN E E KT Sbjct: 624 ATKELSTI-KEQNKELVKQNQDMQTELNDLKKFKQENLTNLQNYLNLMKESETIKTENKS 682 Query: 1522 MQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQL--DNTMNKE 1579 ++T LEN E+ T + NLQ S ++K + A +T + ++L N +N Sbjct: 683 LKTNLENATTELQTTKSNLQNLQK----QSQNLEKRANSAEETAENVLQKLKQQNEINNN 738 Query: 1580 L 1580 L Sbjct: 739 L 739 Score = 61.7 bits (143), Expect = 2e-07 Identities = 81/448 (18%), Positives = 196/448 (43%), Gaps = 24/448 (5%) Query: 1157 LQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLST 1216 L+ + KL +++E TKI L+++ T + + + +++E+LN+E + + Sbjct: 26 LEAEIGKLKNDIEEKKTKISMLQSIIDTTTNERDAANKTVTEQNNRIEKLNSEIQHFVEK 85 Query: 1217 VAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTE-----HELRVQLSAFESKYEQL 1271 ++ I + E +L +++ R+A+ E +LR + +SK +L Sbjct: 86 ESKY-VQIGEQAKKFAAERNKLMEENNLFRQANNNVNEVVESAAKLREENKELQSKVNEL 144 Query: 1272 L---DSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIE 1328 D +S T + + + ++ + Q+ E LR + ++ +I ++++ Sbjct: 145 QKENDDFKSKTLQNQASALLGGFMGLVKGESQEVTE-LRKRHNEREAILAKISTENNQLK 203 Query: 1329 DEKVAFXXXXXXXXXXXXXXXXDLRTENQSYK-QMQEQSILNINEENAQLKKSSXXXXXX 1387 EK+ ++ EN++ K ++Q Q+ N + L+K Sbjct: 204 -EKLQKLEAEKNNNSEYEQIIEEITKENENLKSKLQNQN----NSSDETLRKQLLEKDST 258 Query: 1388 XXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKR 1447 ++ +L + E K+ E K +E +L+ ND+ +N +L + Sbjct: 259 IKSLSDDNKSLSDELEKLDSEKEQKEKEFIAKINELQNSLSNLNDKNKNKISELELQNQA 318 Query: 1448 IEDLTYE-KESELAILRLKMHENANHYETMQKESEIE-RVKLIEELNVKITESVSLNKQV 1505 + + E K + IL K + K SE+E +++ ++++N + + + Sbjct: 319 LNNSLIELKHNNETILMEKQQIETQISNLISKNSELETKLQKMQQMNAGSEQDRDI---I 375 Query: 1506 AELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNL-QNMVRASSSKIQKHVSFASDT 1564 ++L K+LE K ++ EN + E +L EI+ L N+ + + KI+ + + ++ Sbjct: 376 SDLQKSLESSNIKAKNLELTNENLQKEGNSLKLEISKLNSNIEKLNQEKIENN-NKINEL 434 Query: 1565 KQGRDEQLDNTMN-KELLDAVPRAELDL 1591 + ++ L+N N +++++ + + ++++ Sbjct: 435 QLNNEKSLENLQNHQKIIEKLNQEKIEI 462 >UniRef50_Q7SHZ4 Cluster: Putative uncharacterized protein NCU00658.1; n=1; Neurospora crassa|Rep: Putative uncharacterized protein NCU00658.1 - Neurospora crassa Length = 4007 Score = 135 bits (327), Expect = 8e-30 Identities = 262/1403 (18%), Positives = 579/1403 (41%), Gaps = 105/1403 (7%) Query: 213 DTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLE----EANKLLEAA----R 264 D K ++ + + F +A + E L ++ K ++SS E E KL EA R Sbjct: 1355 DLKAELKQDRAEFDKKKALLEGEVATLQGKVDDKSSKLSSKEAEFNELKKLNEAQIAELR 1414 Query: 265 FEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEE-KTEIEEKGSLEIANMTE 323 +++ + + L +LE+ Q E + K + E K S N T Sbjct: 1415 KDVADKSNSLQDKLEELSDLKGQQKTRIEDFNVQINEKMAQLLKAQNELKASQASLNTTT 1474 Query: 324 LTKKIELLEHLNCQIRQTNKELENK--LATMGTESKAVSSPSKKGSPLISRKSGRNTASK 381 T+ + L +++ EL+ K AT TE V +K ++ Sbjct: 1475 -TEYDAKIAQLEKSLKEKKDELKRKEGAATSSTEQNTVQLNKLNDDVKDKQKKLDEQQAE 1533 Query: 382 MKSPWSQLSSET--LNQ---DTDKKINKNEIAKLEMVIQSLNKDLVDK-EYVISEKDTXX 435 + + ++ +ET LNQ DT K+ + E +++ + +KD +D E I+EK T Sbjct: 1534 LNNLKTKHQAETTDLNQTIKDTKAKLKQKETELIDL--KKKHKDRLDTLEKTIAEKQTTL 1591 Query: 436 XXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKD 495 K+T + L+ +++ +M + +G T ++ + L+Q+ +D K Sbjct: 1592 AQ-------KETELENLKAQNRTNMMNTNR-EIGDKTAELLKKEGELRDLRQKYDDAQKL 1643 Query: 496 VN-VKDLIEKLKSAEEQITQLNDEIDAANKN---MIKVKSNHKLKLKQMQKTIDNFSKVS 551 + K+ + ++ I E++ A K+ + K ++ K ++K ++ ++ SK + Sbjct: 1644 ADGSKEKDLAIAQYKQIIATKTSELEKAKKDVAALTKDVNDQKARIKDLESSVS--SKRA 1701 Query: 552 DSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAET 611 D K+ +++ + + L + + + L ++ E K + Sbjct: 1702 DLKKKETEISDLKRQYEENIKRLNNDLSSQKATLTAKEN----EIAALKSGNASRLSRDI 1757 Query: 612 RLKAISLLESQKF--DLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQID 669 + KA L + + +L +L LQ+K +++ K +D ++LQ+D K +++ Sbjct: 1758 QEKASELAQKNQLVANLKVQLDGLQKKQNDLLQKGSDAAKLQADVDSLNKKISEKRQKVT 1817 Query: 670 ALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSA 729 L +L L +K ++ +++ + K+D+ ++ + + ++TD + +S Sbjct: 1818 ELEGKVNKLD---SELAEEKARVSRRDREITDLKKDVSDEKARTTKRDREITDLKKDVSD 1874 Query: 730 EKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVME 789 EK +++ + E + A+ + D I ++S+L ++ LE+ I + Sbjct: 1875 EKAR--VSRRDREVTDLKKDVSDEKARTTKHDNEIGGLQSKLDAKQASKEMLEQDI---K 1929 Query: 790 DRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELV----NRLAVLMDHDRVVEKQLLEIE 845 D + E++ L S + K K Y L L + EK+L EI+ Sbjct: 1930 DLKAKQEKEVASLTSQILAKSKEIVGYERDLSSLKADYQKETTKLKNEISQKEKELAEIQ 1989 Query: 846 HENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLES 905 NK+L N + E+ L S + ++ + +K ++ E+++ K Q + + ++ Sbjct: 1990 KTNKKL---NADIKEKEATLTASQAKVKDLNREVQQKKDQIKDFEAQNAKLQIDIENKKA 2046 Query: 906 NLKRITHEHQTLIVQKKKEIEDLE-IEFNT-QIESAIRDKKVLNEKYEKNIEYVTQLEAQ 963 ++RI E +TL + K I +E +E ++ + +K+ ++Y+ ++ + EA+ Sbjct: 2047 EIERIKEERRTLNTEADKSIARIEGLERKIKELTGSSAEKEAQMKQYQADLAAKAETEAR 2106 Query: 964 LQEYKNNIENLNMNVEELNKM----NLELIDKHVQKQQTQSPDYTEQYINEINKLNALLK 1019 +++ + ++ + ++ E K N++ + TQ + EI ++ Sbjct: 2107 IKQLERDLATKSNSLAEFEKKYKRANMDANNYRSSLAHTQGE--VAKLEEEIKTTKGDVQ 2164 Query: 1020 QKDEEIIALN---QKINNAQVSYMSM-VSDYESKLAQFTTKLENMEEEMQRVSKQLLDSK 1075 ++++I QKI + QV + M V D L +++ +++ R+S+ L+ K Sbjct: 2165 YWEDQMIMNQEETQKIQD-QVDRLKMDVKDKNKILEDHEKEIQTLKDTATRLSQDLIHKK 2223 Query: 1076 QHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXX 1135 E ++ +Q+ +L + + + +G I ++ DD N Sbjct: 2224 SELEGSNSELQRVKNQVAQLTQDNKDQRVVVDTKDGEI--RKLQREVDDLNT----HVMD 2277 Query: 1136 XXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQ 1195 + ++ ++ E ++ + T L+E +I +L N +LT + Sbjct: 2278 KGDQLMKRGEDIKKLRDEIKNFKKDISDHETTLEETMAEIEKLSADNKQLTA-------E 2330 Query: 1196 INQLKSKLEQLNTENDNLLSTVAELRSSISS-AVDQRGFE--IAELWKQHLAQREADFQK 1252 I+ K KL+Q TE D L + + +++S+ D + E +AE K+ +++ + Sbjct: 2331 ISSYKDKLKQSQTEADALNNDIKDMKSTKEKLGQDAKAKETVLAEKMKEIQGLKDS-INR 2389 Query: 1253 TEHELRVQLSAFESKYE---QLLDSVQSSTQE-ETNKIVTMEQVTSLQNKLQDKEEHLRN 1308 ++ + + + K E QL D ++++ +T + ++ L +K +D Sbjct: 2390 LNQDISTKNATLDDKREIIDQLKDDIKTANSTIDTLRKDVKDKDAILAHKTKDVVARDAE 2449 Query: 1309 LQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQ----- 1363 L + A++ ++ L + E+ K AF D+ T+ Q + Sbjct: 2450 LAKLKAEIASKNAALAKKTEEAK-AFEKNVQTLTDQAKGLNQDVATKTTQLAQDRATISK 2508 Query: 1364 -EQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHE 1422 + I ++ + +LK+ + +A + +L +L K++ + +KT E Sbjct: 2509 LNKDIFDLKTDVTKLKQELSTKDANLTQKAGEIGSRDAGLAKLREELRAKEAALAKKTEE 2568 Query: 1423 YTI---TLTQRNDEFENVRQQLVEYEKRI-EDLTYEKESELAILRLKMHENANHYETMQK 1478 + + + DE +++ + + ++ +D + E I +L + QK Sbjct: 2569 ASSLEKNVKKLTDEATGLKKDVTSRDTQLAQDKDAISKLEKDIAKLNQELSTKDASLTQK 2628 Query: 1479 ESEI-----ERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEI 1533 E+ E KL EE+ VK T +++ LN++++ + + + + +E E E+ Sbjct: 2629 TGEVGSKNAELAKLREEIRVKETALAKKTEELKGLNQSVDAKDTQLAQDKIKIERLEKEV 2688 Query: 1534 VTLNDEITNLQNMVRASSSKIQK 1556 L +I L+ V K Sbjct: 2689 KGLTADIVKLREDVAFKDKSFAK 2711 Score = 134 bits (324), Expect = 2e-29 Identities = 275/1415 (19%), Positives = 580/1415 (40%), Gaps = 137/1415 (9%) Query: 240 LKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQS 299 LKDI+S + SLE+ + ++A E L Q+L Q A Q Sbjct: 776 LKDIQSLRLENKSLEDQRQRVQA-------EKEVLQQQLSQTKARLEKVETTLKNTASQK 828 Query: 300 IEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAV 359 ++ + + K LE ++ L K+++L + + E +A T + + Sbjct: 829 MDLETQRNEWSKAKKVLE-EEISRLKKEVDLARKNSAAPTIVEIKPEPNIAESITRVEQL 887 Query: 360 SSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNK 419 K PL +R + +K+K + + D + + + I L V++ Sbjct: 888 MKEQKPQLPLTARDFVQGLVAKLKD-----AQGHKDLDASEDVIRECIGLLNRVLKEPVF 942 Query: 420 DLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIA 479 D DKE + + ++ ++ AQLQ ++ EG +EI Sbjct: 943 DEKDKEMLQTLQNELNEALRKGKEDREQ-SAQLQSIIDKY-EGEKESLEKEVKVHKDEIK 1000 Query: 480 KVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQ 539 K+++++ ++ +D+++ +S EEQI LN + K ++K H+ +L Q Sbjct: 1001 KLKQEITEKKTSLANKQQERDMLK--ESYEEQIKNLNAD---HKKAAAELKVKHQNELTQ 1055 Query: 540 MQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVY 599 ++K D + + L ++L L Q + E E+ LQ DY + + + + Sbjct: 1056 LRK---------DGDLKETNLLQKLDTLRQ---QNESERNRLQ---ADYAAEK---AKLT 1097 Query: 600 KKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEV----EDKLADISQLQSDQV 655 K + + L + K ++ L+S+K ++EL Q+K E+ K D+ QL++ + Sbjct: 1098 KDIEAQKKLVAQKEKDLAELKSKKEKEIKEL--TQKKDVEIATLKSTKQVDMEQLKNRHL 1155 Query: 656 CSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQL--YGTIKD---LENDKEDIMNKL 710 E + + + Q + + E+A + E K D ++L T +D L+ + ++ N Sbjct: 1156 -QETEILRKQHQ-SRVGELESEIATIKEKYKKDLDELSRNNTSQDAIKLKQHENELANFK 1213 Query: 711 QNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQF-----GIDAKIQERDLYIE 765 Y QE L + K E +++ + E+ K+ TQ+ + A++ ++ + Sbjct: 1214 AKYEQEKKQLAVQ-HKTEMESLTD-----RYHEKEKLATQYQERVQALSAELADKKTALA 1267 Query: 766 NIESELSKYKSRICRLEESIAVMEDRRYSLERK------ADQLGSYLQEKQKAYSEYTI- 818 + +LS K+++ +L+ V D + + AD G+ + + K E + Sbjct: 1268 EYKEQLSASKAQLDKLKADHGVKVDELQAKLKSEVAKVTADYEGNLSELRTKHQGEVNVL 1327 Query: 819 ---QEDELVNRLAVLMDHDRVVEKQL----LEIEHENKELQKKNQILLEENQNLQISLSD 871 +DE+ A + R +E ++ E++ + E KK +L E LQ + D Sbjct: 1328 KVHHQDEIKKLTAGHNEKIRNLEHRINDLKAELKQDRAEFDKKKALLEGEVATLQGKVDD 1387 Query: 872 MQQHYNALVEKANR-TDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEI 930 ++ + N L E++ + + + D ++L+ E L Q+K IED Sbjct: 1388 KSSKLSSKEAEFNELKKLNEAQIAELRKDVADKSNSLQDKLEELSDLKGQQKTRIED--- 1444 Query: 931 EFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELID 990 FN QI NEK + ++ +L+A + + +L K E D Sbjct: 1445 -FNVQI----------NEKMAQLLKAQNELKASQASLNTTTTEYDAKIAQLEKSLKEKKD 1493 Query: 991 KHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKL 1050 + +++++ + TEQ ++NKLN +K K +++ ++NN + + + +D + Sbjct: 1494 E-LKRKEGAATSSTEQNTVQLNKLNDDVKDKQKKLDEQQAELNNLKTKHQAETTDLNQTI 1552 Query: 1051 AQFTTKLENMEEE---MQRVSKQLLDSKQHN-EELQILVREQDDQIKELKETKLTFEMNI 1106 KL+ E E +++ K LD+ + E Q + +++ +++ LK T MN Sbjct: 1553 KDTKAKLKQKETELIDLKKKHKDRLDTLEKTIAEKQTTLAQKETELENLKAQNRTNMMNT 1612 Query: 1107 PKTEGMIISSTIEPMSD--DANNV--DXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSA 1162 + G + ++ + D D L + + ++ I ++ E++ Sbjct: 1613 NREIGDKTAELLKKEGELRDLRQKYDDAQKLADGSKEKDLAIAQYKQIIATKTSELEKAK 1672 Query: 1163 K----LNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQ-LNTENDNLLSTV 1217 K L ++ + +I LE+ + + +I+ LK + E+ + N++L S Sbjct: 1673 KDVAALTKDVNDQKARIKDLESSVSSKRADLKKKETEISDLKRQYEENIKRLNNDLSSQK 1732 Query: 1218 AELRSSISSAVDQRGFEIAELWK--QHLAQREADFQKTEHELRVQLSAFESKYEQLLDSV 1275 A L + + + + L + Q A A + L+VQL + K LL Sbjct: 1733 ATLTAKENEIAALKSGNASRLSRDIQEKASELAQKNQLVANLKVQLDGLQKKQNDLLQKG 1792 Query: 1276 QSSTQ-----EETNKIVT--MEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIE 1328 + + + NK ++ ++VT L+ K+ + L + + + +I L+ ++ Sbjct: 1793 SDAAKLQADVDSLNKKISEKRQKVTELEGKVNKLDSELAEEKARVSRRDREITDLKKDVS 1852 Query: 1329 DEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXX 1388 DEK D+ E + +++ + ++ ++ + K + Sbjct: 1853 DEK----ARTTKRDREITDLKKDVSDEKARVSR-RDREVTDLKKDVSDEKARTTKHDNEI 1907 Query: 1389 XXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRI 1448 ++ DA+ E+ Q ++KD + Q+ ++T + +++V YE+ + Sbjct: 1908 GGLQSKL-DAKQASKEMLEQ-DIKDLKAKQEKEVASLT-----SQILAKSKEIVGYERDL 1960 Query: 1449 EDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEE---LNVKITESVSLNKQV 1505 L + + E L+ ++ + +QK ++ + E+ L + LN++V Sbjct: 1961 SSLKADYQKETTKLKNEISQKEKELAEIQKTNKKLNADIKEKEATLTASQAKVKDLNREV 2020 Query: 1506 AELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQ------KHVS 1559 + +++ A+ ++Q +EN++ EI + +E L S ++I+ K ++ Sbjct: 2021 QQKKDQIKDFEAQNAKLQIDIENKKAEIERIKEERRTLNTEADKSIARIEGLERKIKELT 2080 Query: 1560 FASDTK--QGRDEQLDNTMNKELLDAVPRAELDLA 1592 +S K Q + Q D E + + E DLA Sbjct: 2081 GSSAEKEAQMKQYQADLAAKAETEARIKQLERDLA 2115 Score = 132 bits (318), Expect = 1e-28 Identities = 285/1465 (19%), Positives = 598/1465 (40%), Gaps = 157/1465 (10%) Query: 143 DVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEK-DQIIEAKN--KATTXXXXX 199 DV SN++++K LS L+ + K T I D +INEK Q+++A+N KA+ Sbjct: 1416 DVADKSNSLQDKLEELSDLKGQQK---TRIEDFNVQINEKMAQLLKAQNELKASQASLNT 1472 Query: 200 XXXXXXXXXXXXEDT---KQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEA 256 E + K+ K +E E + L D + KD + L+E Sbjct: 1473 TTTEYDAKIAQLEKSLKEKKDELKRKEGAATSSTEQNTVQLNKLND-DVKDKQ-KKLDEQ 1530 Query: 257 NKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSL 316 L + + E + L Q ++ L K+ +++ + EK Sbjct: 1531 QAELNNLKTKHQAETTDLNQTIKDTKAKLKQKETELIDLKKKH-----KDRLDTLEKTIA 1585 Query: 317 EIANMTELTKKIELLEHLNCQIR----QTNKELENKLATMGTESKAVSSPSKKGSPLISR 372 E T L +K LE+L Q R TN+E+ +K A + KK L Sbjct: 1586 E--KQTTLAQKETELENLKAQNRTNMMNTNREIGDKTAEL----------LKKEGELRDL 1633 Query: 373 KSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKD 432 + + A K+ + +E+ K + + +L KD+ D++ I + + Sbjct: 1634 RQKYDDAQKLADGSKEKDLAIAQYKQIIATKTSELEKAKKDVAALTKDVNDQKARIKDLE 1693 Query: 433 TXXXXXXXXXXGKDTLIAQLQLEHQQHME---GPSLIHVGTNTEDVNEIAKVQEQLKQEL 489 + K+T I+ L+ +++++++ T T NEIA ++ L Sbjct: 1694 SSVSSKRADLKKKETEISDLKRQYEENIKRLNNDLSSQKATLTAKENEIAALKSGNASRL 1753 Query: 490 NDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANK--NMIKVKSNHKLKLKQMQKTIDNF 547 + +I++ +L +K + + L ++D K N + K + KL Q +D+ Sbjct: 1754 SRDIQE-KASELAQK----NQLVANLKVQLDGLQKKQNDLLQKGSDAAKL---QADVDSL 1805 Query: 548 SK-VSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEME 606 +K +S+ +++ L +++ L +EL EEK + S R E KK + E Sbjct: 1806 NKKISEKRQKVTELEGKVNKLD---SELAEEKARV--------SRRDREITDLKKDVSDE 1854 Query: 607 NLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEE 666 A T + + + +K D+ E + ++ EV D D+S ++ + + L+ Sbjct: 1855 K-ARTTKRDREITDLKK-DVSDEKARVSRRDREVTDLKKDVSDEKARTTKHDNEIGGLQS 1912 Query: 667 QIDALSASKKELALVIENLKLDKE--------QLYGTIKDLENDKEDIMNKLQNYIQENM 718 ++DA ASK+ L I++LK +E Q+ K++ + D+ + +Y +E Sbjct: 1913 KLDAKQASKEMLEQDIKDLKAKQEKEVASLTSQILAKSKEIVGYERDLSSLKADYQKETT 1972 Query: 719 DLTDKLEKMSAE--KISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKS 776 L +++ + E +I + K+N + + K T AK+++ + ++ + ++ +++ Sbjct: 1973 KLKNEISQKEKELAEIQKTNKKLNADIKEKEATLTASQAKVKDLNREVQQKKDQIKDFEA 2032 Query: 777 RICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRV 836 + +L+ I E+++ +ER ++E+++ + + D+ + R+ L + Sbjct: 2033 QNAKLQIDI---ENKKAEIER--------IKEERRTLNT---EADKSIARIEGLERKIKE 2078 Query: 837 VEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKY 896 + E E + K+ Q E ++ D+ N+L E + A ++ Y Sbjct: 2079 LTGSSAEKEAQMKQYQADLAAKAETEARIKQLERDLATKSNSLAEFEKKYKRANMDANNY 2138 Query: 897 QTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEY 956 ++ L + + ++ E +T K +++ E D+ ++N++ Sbjct: 2139 RSSLAHTQGEVAKLEEEIKTT----KGDVQYWE------------DQMIMNQE------- 2175 Query: 957 VTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKL-- 1014 + Q+ ++ ++ L M+V++ NK+ LE +K +Q + + ++ I++ ++L Sbjct: 2176 ------ETQKIQDQVDRLKMDVKDKNKI-LEDHEKEIQTLKDTATRLSQDLIHKKSELEG 2228 Query: 1015 -NALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLL- 1072 N+ L++ ++ L Q + +V +V + ++ + +++++ + QL+ Sbjct: 2229 SNSELQRVKNQVAQLTQDNKDQRV----VVDTKDGEIRKLQREVDDLNTHVMDKGDQLMK 2284 Query: 1073 ---DSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVD 1129 D K+ +E++ ++ D L+ET E + +++ I D Sbjct: 2285 RGEDIKKLRDEIKNFKKDISDHETTLEETMAEIEKL--SADNKQLTAEISSYKDKLKQSQ 2342 Query: 1130 XXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQL-ETLNTELTGH 1188 +K +E+ Q+ + A+ E+Q I +L + ++T+ Sbjct: 2343 TEADALNNDIKDMK-STKEKLGQDAKAKETVLAEKMKEIQGLKDSINRLNQDISTKNATL 2401 Query: 1189 DVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSA---VDQRGFEIAELWKQHLAQ 1245 D +E I+QLK ++ N+ D L V + + ++ V R E+A+L K +A Sbjct: 2402 DD-KREIIDQLKDDIKTANSTIDTLRKDVKDKDAILAHKTKDVVARDAELAKL-KAEIAS 2459 Query: 1246 READFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQ----VTSLQNKLQD 1301 + A K E + AFE + L D + Q+ K + Q ++ L + D Sbjct: 2460 KNAALAKKTEEAK----AFEKNVQTLTDQAKGLNQDVATKTTQLAQDRATISKLNKDIFD 2515 Query: 1302 KEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQ 1361 + + L+++ + + EI +TE S Sbjct: 2516 LKTDVTKLKQELSTKDANLTQKAGEIGSRDAGLAKLREELRAKEAALAK--KTEEAS--- 2570 Query: 1362 MQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTH 1421 E+++ + +E LKK ++ E + +L +L KD+ + QKT Sbjct: 2571 SLEKNVKKLTDEATGLKKDVTSRDTQLAQDKDAISKLEKDIAKLNQELSTKDASLTQKTG 2630 Query: 1422 EYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESE 1481 E + E +R + K+ E+L +S A ++ ++ E ++KE + Sbjct: 2631 EVGSKNAELAKLREEIRVKETALAKKTEELKGLNQSVDA-KDTQLAQDKIKIERLEKEVK 2689 Query: 1482 ---IERVKLIEELN------VKITESVS-LNKQVAELNKALEEEVAKTNEMQTALENQEI 1531 + VKL E++ K E+V L + ELN + + + A+ +E Sbjct: 2690 GLTADIVKLREDVAFKDKSFAKKAEAVDHLKADITELNSEVAKLKKEGTNKDAAILGKEK 2749 Query: 1532 EIVTLNDEITNLQNMVRASSSKIQK 1556 E+V+L + +L N + S+ +K Sbjct: 2750 ELVSLRKAVRDLTNQAKQSAQDSKK 2774 Score = 130 bits (313), Expect = 4e-28 Identities = 302/1593 (18%), Positives = 659/1593 (41%), Gaps = 146/1593 (9%) Query: 53 KFERAQKCLENAALVSKRIKEHRKATAELLGRPFVPGISESLANTLKQKEILMEKIK-QY 111 K +K ++ A ++K + + + +L +S A+ LK+KE + +K QY Sbjct: 1664 KTSELEKAKKDVAALTKDVNDQKARIKDLES-----SVSSKRAD-LKKKETEISDLKRQY 1717 Query: 112 KELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNALSVLQVKMKIMETT 171 +E KR + + + G+ + LS I+EK + L+ + ++ Sbjct: 1718 EENIKRLNNDLSSQKATLTAKENEIAALKSGNASRLSRDIQEKASELAQKNQLVANLKVQ 1777 Query: 172 ILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAE 231 + LQ+K N+ +++ + A + +Q++T+++ +++E Sbjct: 1778 LDGLQKKQND---LLQKGSDAAKLQADVDSLNKKIS-----EKRQKVTELEGKVNKLDSE 1829 Query: 232 WKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXX 291 +EK R + +D I+ L++ +A + E + L +++ Sbjct: 1830 LAEEKAR----VSRRDREITDLKKDVSDEKARTTKRDREITDLKKDVSDEKARVSRRDRE 1885 Query: 292 XXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLAT 351 L K + E G L+ ++L K E L I+ + E ++A+ Sbjct: 1886 VTDLKKDVSDEKARTTKHDNEIGGLQ----SKLDAKQASKEMLEQDIKDLKAKQEKEVAS 1941 Query: 352 MGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLE 411 + ++ A K ++ + S +K+ + + +++ N+ + K+ E+A+++ Sbjct: 1942 LTSQILA------KSKEIVGYE---RDLSSLKADYQKETTKLKNEISQKE---KELAEIQ 1989 Query: 412 MVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTN 471 + LN D+ +KE ++ K I + ++ + I + Sbjct: 1990 KTNKKLNADIKEKEATLTASQAKVKDLNREVQQKKDQIKDFEAQNAKLQ-----IDIENK 2044 Query: 472 TEDVNEIAKVQEQLKQELNDEIKDVN-----VKDLIEKLKSAEEQITQLNDEIDAANKNM 526 ++ I + + L E + I + +K+L E Q+ Q ++ A + Sbjct: 2045 KAEIERIKEERRTLNTEADKSIARIEGLERKIKELTGSSAEKEAQMKQYQADLAAKAETE 2104 Query: 527 IKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEE----KGNLQ 582 ++K + + + K +N + L H +VA+LEEE KG++Q Sbjct: 2105 ARIKQLERDLATKSNSLAEFEKKYKRANMDANNYRSSLAHTQGEVAKLEEEIKTTKGDVQ 2164 Query: 583 LH----LVDYDSGRMIESDVYKKMIEMEN---LAETRLKAISLLESQKFDLVQ------- 628 +++ + + I+ V + +++++ + E K I L+ L Q Sbjct: 2165 YWEDQMIMNQEETQKIQDQVDRLKMDVKDKNKILEDHEKEIQTLKDTATRLSQDLIHKKS 2224 Query: 629 ELHILQQKYDEVEDKLADISQLQSDQ-VCSEIKSVH---LEEQIDALSA----SKKELAL 680 EL + V++++A ++Q DQ V + K L+ ++D L+ +L Sbjct: 2225 ELEGSNSELQRVKNQVAQLTQDNKDQRVVVDTKDGEIRKLQREVDDLNTHVMDKGDQLMK 2284 Query: 681 VIENLKLDKEQLYGTIKDL---ENDKEDIMNKLQNYIQENMDLTDKLEKMSAE-KISELL 736 E++K ++++ KD+ E E+ M +++ +N LT ++ + K S+ Sbjct: 2285 RGEDIKKLRDEIKNFKKDISDHETTLEETMAEIEKLSADNKQLTAEISSYKDKLKQSQTE 2344 Query: 737 AK-INHE--EQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESI----AVME 789 A +N++ + + + G DAK +E L E ++ E+ K I RL + I A ++ Sbjct: 2345 ADALNNDIKDMKSTKEKLGQDAKAKETVL-AEKMK-EIQGLKDSINRLNQDISTKNATLD 2402 Query: 790 DRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENK 849 D+R +++ D + + + ++ L ++ ++ D + K EI +N Sbjct: 2403 DKREIIDQLKDDIKTANSTIDTLRKDVKDKDAILAHKTKDVVARDAELAKLKAEIASKNA 2462 Query: 850 ELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESEST--KYQTQLRDLESNL 907 L KK + +N+Q +L+D + N V T LA+ +T K + DL++++ Sbjct: 2463 ALAKKTEEAKAFEKNVQ-TLTDQAKGLNQDVA-TKTTQLAQDRATISKLNKDIFDLKTDV 2520 Query: 908 KRITHEHQTL---IVQKKKEIEDLEI---EFNTQI---ESAIRDKKVLNEKYEKNIEYVT 958 ++ E T + QK EI + + ++ E+A+ K EKN++ +T Sbjct: 2521 TKLKQELSTKDANLTQKAGEIGSRDAGLAKLREELRAKEAALAKKTEEASSLEKNVKKLT 2580 Query: 959 QLEAQLQ-EYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNAL 1017 L+ + + L + + ++K+ + I K Q+ T+ T++ E+ NA Sbjct: 2581 DEATGLKKDVTSRDTQLAQDKDAISKLEKD-IAKLNQELSTKDASLTQK-TGEVGSKNAE 2638 Query: 1018 LKQKDEEI----IALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLD 1073 L + EEI AL +K + S V +++LAQ K+E +E+E++ ++ ++ Sbjct: 2639 LAKLREEIRVKETALAKKTEELKGLNQS-VDAKDTQLAQDKIKIERLEKEVKGLTADIVK 2697 Query: 1074 SKQHNEELQILVREQDDQIKELKE--TKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXX 1131 ++ ++ + + LK T+L E+ K EG + I + ++ Sbjct: 2698 LREDVAFKDKSFAKKAEAVDHLKADITELNSEVAKLKKEGTNKDAAILGKEKELVSLRKA 2757 Query: 1132 XXXXXXXX--XXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQL-ETLN-TELTG 1187 ++ E + R L ++ K ELQ+ K+ E LN T T Sbjct: 2758 VRDLTNQAKQSAQDSKKSAEDLANRDALLKEKEKKIFELQQEIQKVKDTAEELNQTTKTR 2817 Query: 1188 HDVVNQ--EQINQLKSKLEQLNTENDNLLSTVAELRSSIS---SAVDQRGFEIAELWKQ- 1241 ++Q E++ +L+ +++QL E ++L L +I+ S+++Q+ EI+ L K+ Sbjct: 2818 DSTLSQKNEELRKLREQIKQLEDEANSLKMDKETLGRTINTRDSSLEQKEQEISGLEKEI 2877 Query: 1242 -HLAQREADFQKTEHELRVQLSAFESKYEQL---LDSVQSSTQEETNKIVTMEQVTSLQN 1297 L+++ A+ + + +L + A ++ Q +D ++ S + K + ++ + Q+ Sbjct: 2878 KRLSEQAANLTQEKVDLGQIVGARDASLLQANKDIDGLKGSIKILEEKAAELSKLNAGQD 2937 Query: 1298 K-LQDKEEHLRNLQEKYADVINQIEILRSE---IEDEKVAFXXXXXXXXXXXXXXXXDLR 1353 + + +K+ L+ E ++ ++ L ++ + +EK D++ Sbjct: 2938 QTIGEKDASLQKANEDIDNLKGSVQKLENKAATLAEEKAQMGQTIGAHETSLLKKDEDIK 2997 Query: 1354 TENQSYKQMQ-EQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQ---L 1409 + +++ E + L EN L + + E + +L + L Sbjct: 2998 KLTANIQRLTAEANDLKKGIEN--LTGDIAIQNRALAQKEKDIQNMEKTIQDLNTEVARL 3055 Query: 1410 ELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIE-------DLTYEKESELAIL 1462 + +E QKT TLT +ND+ + Q+ + + DL S+ +L Sbjct: 3056 KTNAAEHNQKTIAKDATLTAKNDQISKLNDQIKQLRAEVTKLKSDAADLNQATTSKDIVL 3115 Query: 1463 RLKMHE-NANHYETMQKESEIER-----VKLIEELNVKITESVS-LNKQVAELNKALEEE 1515 +M E N E ++ ++ ++ +E+N ++ E+V L + +L K + Sbjct: 3116 AQRMEEINGLRNEMVELNKALDTRDTTFLQNTDEIN-RLKENVRRLGDETTKLKKDTVKL 3174 Query: 1516 VAKTNEMQTALENQEIEIVTLNDEITNLQNMVR 1548 + + ++ ++ EI LND I NLQ ++ Sbjct: 3175 KEDSKSWEETVKQRQTEINKLNDNIKNLQEEIK 3207 Score = 119 bits (287), Expect = 6e-25 Identities = 257/1310 (19%), Positives = 518/1310 (39%), Gaps = 112/1310 (8%) Query: 328 IELLEHLNCQIRQTNKEL-ENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPW 386 +E+ +++ T + L + + A E+ A S ++ S I + + N K + Sbjct: 602 LEVFDNILNLYEDTEQRLVQTEEAKDKAEAAAKESATRSRSETIQKLTSENNKLKEQRDE 661 Query: 387 SQLSSETLNQDTDKK--INKNEIAKLEMVI-QSLNKDLVDKEYVISEKDTXXXXXXXXXX 443 + ++ Q KK + E + + Q KD D+ SEK+ Sbjct: 662 QKRKADAFYQKLKKKGWLEPTEDPSASLALDQKSLKDQQDRWE--SEKNALNQKITNLNK 719 Query: 444 GKDTLIAQLQLEHQQHMEGPSLIHVGTNTE-DVNEIAKVQEQLKQELNDEIK-DVNVKDL 501 + L+ +E SL+ + E D+ + + LKQ+L + ++KD Sbjct: 720 SIEEANVALKDMKLMQVERDSLVDLQQRQEGDIKSLNQQVLDLKQKLASKASAGADLKD- 778 Query: 502 IEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLT 561 I+ L+ + + + A + + + S K +L++++ T+ N + S K + L Sbjct: 779 IQSLRLENKSLEDQRQRVQAEKEVLQQQLSQTKARLEKVETTLKNTA----SQK--MDLE 832 Query: 562 EELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLES 621 + + S+ LEEE L+ VD + + E N+AE+ + L++ Sbjct: 833 TQRNEWSKAKKVLEEEISRLKKE-VDLARKNSAAPTIVEIKPE-PNIAESITRVEQLMKE 890 Query: 622 QKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALV 681 QK +L + + D V+ +A + Q + + V + E I L+ KE Sbjct: 891 QK----PQLPLTAR--DFVQGLVAKLKDAQGHKDLDASEDV-IRECIGLLNRVLKEPVFD 943 Query: 682 IENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKIS-ELLAKIN 740 + DKE L + L+N+ + + K + +++ L ++K EK S E K++ Sbjct: 944 ----EKDKEML----QTLQNELNEALRKGKEDREQSAQLQSIIDKYEGEKESLEKEVKVH 995 Query: 741 HEEQSKIQTQF-----GIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSL 795 +E K++ + + K QERD+ E+ E ++ + + + V + Sbjct: 996 KDEIKKLKQEITEKKTSLANKQQERDMLKESYEEQIKNLNADHKKAAAELKVKHQNELTQ 1055 Query: 796 ERKADQLG--SYLQE----KQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENK 849 RK L + LQ+ +Q+ SE + + A L +K + + E + Sbjct: 1056 LRKDGDLKETNLLQKLDTLRQQNESERNRLQADYAAEKAKLTKDIEAQKKLVAQKEKDLA 1115 Query: 850 ELQ-KKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLR--DLESN 906 EL+ KK + + E Q + ++ ++ +E+ L E+E + Q Q R +LES Sbjct: 1116 ELKSKKEKEIKELTQKKDVEIATLKSTKQVDMEQLKNRHLQETEILRKQHQSRVGELESE 1175 Query: 907 LKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKN--IEYVTQLEAQL 964 + I +++ + + + + Q E+ + + K E+ +K +++ T++E+ Sbjct: 1176 IATIKEKYKKDLDELSRNNTSQDAIKLKQHENELANFKAKYEQEKKQLAVQHKTEMESLT 1235 Query: 965 QEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEE 1024 Y + E + ++ EL DK +T +Y EQ +L+ L + Sbjct: 1236 DRYHEKEKLATQYQERVQALSAELADK-----KTALAEYKEQLSASKAQLDKLKADHGVK 1290 Query: 1025 IIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQ---HNEEL 1081 + L K+ + + +DYE L++ TK + E + +V Q K HNE++ Sbjct: 1291 VDELQAKLKS---EVAKVTADYEGNLSELRTKHQG-EVNVLKVHHQDEIKKLTAGHNEKI 1346 Query: 1082 QILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXX 1141 + L +D ELK+ + F+ EG + +T++ DD ++ Sbjct: 1347 RNLEHRINDLKAELKQDRAEFDKKKALLEGEV--ATLQGKVDDKSS---KLSSKEAEFNE 1401 Query: 1142 LKVQEEEEFIQERSVLQEQSAKLNTELQECYT----KIIQLETLNTELTGHDVVNQEQIN 1197 LK E + + R + ++S L +L+E + ++E N ++ + N Sbjct: 1402 LKKLNEAQIAELRKDVADKSNSLQDKLEELSDLKGQQKTRIEDFNVQINEKMAQLLKAQN 1461 Query: 1198 QLKSKLEQLNTENDNLLSTVAELRSSISSAVDQ---RGFEIAELWKQHLAQREA------ 1248 +LK+ LNT + +A+L S+ D+ + +Q+ Q Sbjct: 1462 ELKASQASLNTTTTEYDAKIAQLEKSLKEKKDELKRKEGAATSSTEQNTVQLNKLNDDVK 1521 Query: 1249 DFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTME-QVTSLQNKLQDK----E 1303 D QK E + +L+ ++K++ + + ++ K+ E ++ L+ K +D+ E Sbjct: 1522 DKQKKLDEQQAELNNLKTKHQAETTDLNQTIKDTKAKLKQKETELIDLKKKHKDRLDTLE 1581 Query: 1304 EHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQ 1363 + + Q A ++E L+++ + +LR Q Y Q Sbjct: 1582 KTIAEKQTTLAQKETELENLKAQNRTNMMNTNREIGDKTAELLKKEGELRDLRQKYDDAQ 1641 Query: 1364 E----------------QSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTH 1407 + Q I E + KK R+ D E+ V Sbjct: 1642 KLADGSKEKDLAIAQYKQIIATKTSELEKAKKDVAALTKDVNDQKARIKDLESSVSSKRA 1701 Query: 1408 QLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLT-----------YEKE 1456 L+ K++EI +Y + + N++ + + L E I L EK Sbjct: 1702 DLKKKETEISDLKRQYEENIKRLNNDLSSQKATLTAKENEIAALKSGNASRLSRDIQEKA 1761 Query: 1457 SELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEV 1516 SELA + + +QK+ K + ++ + SLNK+++E + + E Sbjct: 1762 SELAQKNQLVANLKVQLDGLQKKQNDLLQKGSDAAKLQ-ADVDSLNKKISEKRQKVTELE 1820 Query: 1517 AKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQ 1566 K N++ + L ++ + + EIT+L+ V ++ K +D K+ Sbjct: 1821 GKVNKLDSELAEEKARVSRRDREITDLKKDVSDEKARTTKRDREITDLKK 1870 Score = 111 bits (266), Expect = 2e-22 Identities = 295/1610 (18%), Positives = 630/1610 (39%), Gaps = 170/1610 (10%) Query: 57 AQKCLENAALVSKRIKEHRKATAELLGRPFVPGISESLANTLKQKEILMEKIKQYKELSK 116 A K + ++K+I E R+ EL G+ V + LA ++K + + ++ +L K Sbjct: 1795 AAKLQADVDSLNKKISEKRQKVTELEGK--VNKLDSELA---EEKARVSRRDREITDLKK 1849 Query: 117 RSSTTIVRXXXXXXXXXXXXX--XXQLGDVTHLSNTIKEKDNALSVLQVKMKIMETTILD 174 S R + V+ + + +S + + + I Sbjct: 1850 DVSDEKARTTKRDREITDLKKDVSDEKARVSRRDREVTDLKKDVSDEKARTTKHDNEIGG 1909 Query: 175 LQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKD 234 LQ K++ K E + +++ + + +++A+++ Sbjct: 1910 LQSKLDAKQASKEMLEQDIKDLKAKQEKEVASLTSQILAKSKEIVGYERDLSSLKADYQK 1969 Query: 235 EKQRLLKDIESKDVRISSLEEANKLLEA--ARFEISLEHSK-----LAQELEQXXXXXXX 287 E +L +I K+ ++ +++ NK L A E +L S+ L +E++Q Sbjct: 1970 ETTKLKNEISQKEKELAEIQKTNKKLNADIKEKEATLTASQAKVKDLNREVQQKKDQIKD 2029 Query: 288 XXXXXXXLA------KQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLE----HLNCQ 337 L K IE EE+ + + IA + L +KI+ L Q Sbjct: 2030 FEAQNAKLQIDIENKKAEIERIKEERRTLNTEADKSIARIEGLERKIKELTGSSAEKEAQ 2089 Query: 338 IRQTNKELENKLAT----------MGTESKAVSSPSKKGSPL-ISRKSGRNTASKMKSPW 386 ++Q +L K T + T+S +++ KK + + R++ + + Sbjct: 2090 MKQYQADLAAKAETEARIKQLERDLATKSNSLAEFEKKYKRANMDANNYRSSLAHTQGEV 2149 Query: 387 SQLSSE--TLNQDT----DKKI-NKNEIAKLEMVIQSLNKDLVDKEYVIS--EKDTXXXX 437 ++L E T D D+ I N+ E K++ + L D+ DK ++ EK+ Sbjct: 2150 AKLEEEIKTTKGDVQYWEDQMIMNQEETQKIQDQVDRLKMDVKDKNKILEDHEKEIQTLK 2209 Query: 438 XXXXXXGKDTLIAQLQLEHQ----QHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEI 493 +D + + +LE Q ++ + + + +D + ++ ++L E+ Sbjct: 2210 DTATRLSQDLIHKKSELEGSNSELQRVKN-QVAQLTQDNKDQRVVVDTKDGEIRKLQREV 2268 Query: 494 KDVN--VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVS 551 D+N V D ++L E I +L DEI KN K S+H+ L++ T+ K+S Sbjct: 2269 DDLNTHVMDKGDQLMKRGEDIKKLRDEI----KNFKKDISDHETTLEE---TMAEIEKLS 2321 Query: 552 DSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDS--------GRMIESDVYKKMI 603 NK+ LT E+ K+ + + E L + D S + E+ + +KM Sbjct: 2322 ADNKQ---LTAEISSYKDKLKQSQTEADALNNDIKDMKSTKEKLGQDAKAKETVLAEKMK 2378 Query: 604 EMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVH 663 E++ L ++ + + ++ L + I+ Q D+++ + I L+ D + H Sbjct: 2379 EIQGLKDSINRLNQDISTKNATLDDKREIIDQLKDDIKTANSTIDTLRKDVKDKDAILAH 2438 Query: 664 LEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDK 723 + + A A +L I + + K E + + + ++ + Q+ T + Sbjct: 2439 KTKDVVARDAELAKLKAEIASKNAALAKKTEEAKAFEKNVQTLTDQAKGLNQDVATKTTQ 2498 Query: 724 L--EKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRL 781 L ++ + K+++ + + + Q DA + ++ I + ++ L+K + + Sbjct: 2499 LAQDRATISKLNKDIFDLKTDVTKLKQELSTKDANLTQKAGEIGSRDAGLAKLREELRAK 2558 Query: 782 EESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQL 841 E ++A + SLE+ +L E + T ++ +L + ++ + K Sbjct: 2559 EAALAKKTEEASSLEKNVKKL---TDEATGLKKDVTSRDTQLAQDKDAISKLEKDIAKLN 2615 Query: 842 LEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANR-------TDLAESEST 894 E+ ++ L +K + +N L +++ AL +K D +++ Sbjct: 2616 QELSTKDASLTQKTGEVGSKNAELAKLREEIRVKETALAKKTEELKGLNQSVDAKDTQLA 2675 Query: 895 KYQTQLRDLESNLKRITHEHQTL----------IVQKKKEIEDLEI---EFNTQI----- 936 + + ++ LE +K +T + L +K + ++ L+ E N+++ Sbjct: 2676 QDKIKIERLEKEVKGLTADIVKLREDVAFKDKSFAKKAEAVDHLKADITELNSEVAKLKK 2735 Query: 937 ESAIRDKKVLNEKYEKNIEYVTQLEAQL-QEYKNNIENLNMNVEELNKMNLELIDKHVQ- 994 E +D +L + EK + + + L + K + ++ + E+L + L +K + Sbjct: 2736 EGTNKDAAILGK--EKELVSLRKAVRDLTNQAKQSAQDSKKSAEDLANRDALLKEKEKKI 2793 Query: 995 ---KQQTQSPDYTEQYINEINKL-NALLKQKDEEIIALNQKINNAQVSYMSMVSDYE--- 1047 +Q+ Q T + +N+ K ++ L QK+EE+ L ++I + S+ D E Sbjct: 2794 FELQQEIQKVKDTAEELNQTTKTRDSTLSQKNEELRKLREQIKQLEDEANSLKMDKETLG 2853 Query: 1048 -------SKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQD----------D 1090 S L Q ++ +E+E++R+S+Q + Q +L +V +D D Sbjct: 2854 RTINTRDSSLEQKEQEISGLEKEIKRLSEQAANLTQEKVDLGQIVGARDASLLQANKDID 2913 Query: 1091 QIK---ELKETKLTFEMNIPKTEGMII---SSTIEPMSDDANNVDXXXXXXXXXXXXL-- 1142 +K ++ E K + + I ++++ ++D +N+ L Sbjct: 2914 GLKGSIKILEEKAAELSKLNAGQDQTIGEKDASLQKANEDIDNLKGSVQKLENKAATLAE 2973 Query: 1143 -KVQEEEEF-IQERSVLQ--EQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQ 1198 K Q + E S+L+ E KL +Q + L+ LTG + + Q Sbjct: 2974 EKAQMGQTIGAHETSLLKKDEDIKKLTANIQRLTAEANDLKKGIENLTGDIAIQNRALAQ 3033 Query: 1199 LKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELR 1258 + ++ + +L + VA L+ ++A + IA+ L + K +++ Sbjct: 3034 KEKDIQNMEKTIQDLNTEVARLK---TNAAEHNQKTIAK--DATLTAKNDQISKLNDQIK 3088 Query: 1259 VQLSAFESKYE-QLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVI 1317 QL A +K + D Q++T ++ ME++ L+N++ + + L + Sbjct: 3089 -QLRAEVTKLKSDAADLNQATTSKDIVLAQRMEEINGLRNEMVELNKALDTRDTTFLQNT 3147 Query: 1318 NQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQL 1377 ++I L+ + D ++ ++ KQ Q + I +N+ L Sbjct: 3148 DEINRLKENVR----RLGDETTKLKKDTVKLKEDSKSWEETVKQRQTE-INKLNDNIKNL 3202 Query: 1378 KKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENV 1437 ++ +N + +++ L L KD++ L R+ E Sbjct: 3203 QEEIKRKEALLATRQGEINALKDEIVGLKKDLAEKDAQ-----------LKSRDGELGKF 3251 Query: 1438 RQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITE 1497 R+ + E +E L E E LR K+ ++ ++ K++E N + Sbjct: 3252 RKSIAAKETALERL----EKEKTALREKVEHLEGEVGRRRRSLDLRADKILELTNSESAA 3307 Query: 1498 SVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMV 1547 + L+KQ A NK+LEE ++ + + L DE+T L + Sbjct: 3308 RLDLDKQRAR-NKSLEE---TNTGLRNRAAKEGGSLGRLGDEVTKLSRQL 3353 Score = 108 bits (259), Expect = 1e-21 Identities = 271/1416 (19%), Positives = 557/1416 (39%), Gaps = 121/1416 (8%) Query: 144 VTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKAT--TXXXXXXX 201 V L +K+K+ L + +++ ++ T L + + K +E N Sbjct: 2184 VDRLKMDVKDKNKILEDHEKEIQTLKDTATRLSQDLIHKKSELEGSNSELQRVKNQVAQL 2243 Query: 202 XXXXXXXXXXEDTKQ-QMTKMQENFIAMEAEWKDEKQRLLK---DIESKDVRISSLEEAN 257 DTK ++ K+Q + D+ +L+K DI+ I + ++ Sbjct: 2244 TQDNKDQRVVVDTKDGEIRKLQREVDDLNTHVMDKGDQLMKRGEDIKKLRDEIKNFKKDI 2303 Query: 258 KLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQS--IEPSCEEKTEIEEK-G 314 E E E KL+ + +Q ++ + ++ +EK G Sbjct: 2304 SDHETTLEETMAEIEKLSADNKQLTAEISSYKDKLKQSQTEADALNNDIKDMKSTKEKLG 2363 Query: 315 SLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKS 374 A T L +K++ ++ L I + N+++ K AT+ + + + K+ Sbjct: 2364 QDAKAKETVLAEKMKEIQGLKDSINRLNQDISTKNATLDDKREIIDQLKD------DIKT 2417 Query: 375 GRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDK--EYVISEKD 432 +T ++ + ++ D E+AKL+ I S N L K E EK+ Sbjct: 2418 ANSTIDTLRKDVKDKDAILAHKTKDVVARDAELAKLKAEIASKNAALAKKTEEAKAFEKN 2477 Query: 433 TXXXXXXXXXXGKDTLIAQLQLEHQQ---HMEGPSLIHVGTN-TEDVNEIAKVQEQLKQE 488 +D QL + + + T+ T+ E++ L Q+ Sbjct: 2478 VQTLTDQAKGLNQDVATKTTQLAQDRATISKLNKDIFDLKTDVTKLKQELSTKDANLTQK 2537 Query: 489 LND-EIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNF 547 + +D + L E+L++ E + + +E + KN+ K+ K + Sbjct: 2538 AGEIGSRDAGLAKLREELRAKEAALAKKTEEASSLEKNVKKLTDEATGLKKDVTSRDTQL 2597 Query: 548 SKVSDS----NKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDY-DSGRMIESDVYKKM 602 ++ D+ K+I +L +EL + + E G+ L + R+ E+ + KK Sbjct: 2598 AQDKDAISKLEKDIAKLNQELSTKDASLTQKTGEVGSKNAELAKLREEIRVKETALAKKT 2657 Query: 603 IEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSV 662 E++ L ++ ++++ L Q+ +++ EV+ ADI +L+ D + Sbjct: 2658 EELKGLNQS-------VDAKDTQLAQDKIKIERLEKEVKGLTADIVKLREDVAFKDKSFA 2710 Query: 663 HLEEQIDALSASKKELALVIENLKLDKEQ----LYGTIKDLENDKE---DIMNKLQNYIQ 715 E +D L A EL + LK + + G K+L + ++ D+ N+ + Q Sbjct: 2711 KKAEAVDHLKADITELNSEVAKLKKEGTNKDAAILGKEKELVSLRKAVRDLTNQAKQSAQ 2770 Query: 716 ENMDLTDKLEKMSA--EKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSK 773 ++ + L A ++ + + ++ E Q T ++ + RD + EL K Sbjct: 2771 DSKKSAEDLANRDALLKEKEKKIFELQQEIQKVKDTAEELNQTTKTRDSTLSQKNEELRK 2830 Query: 774 YKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYS----EYTIQEDELVNRLAV 829 + +I +LE+ ++ + +L R + S L++K++ S E ++ N Sbjct: 2831 LREQIKQLEDEANSLKMDKETLGRTINTRDSSLEQKEQEISGLEKEIKRLSEQAANLTQE 2890 Query: 830 LMDHDRVVEKQLLEIEHENKELQK-KNQILLEENQNLQISLSDMQQHY-----NALVEKA 883 +D ++V + + NK++ K I + E + ++S + Q +A ++KA Sbjct: 2891 KVDLGQIVGARDASLLQANKDIDGLKGSIKILEEKAAELSKLNAGQDQTIGEKDASLQKA 2950 Query: 884 NRT-DLAESESTKYQTQ---LRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESA 939 N D + K + + L + ++ + + H+T +++K ++I+ L ++ + Sbjct: 2951 NEDIDNLKGSVQKLENKAATLAEEKAQMGQTIGAHETSLLKKDEDIKKLTANIQ-RLTAE 3009 Query: 940 IRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQ-KQQT 998 D K E +I + AQ ++ +I+N+ +++LN L + Q+T Sbjct: 3010 ANDLKKGIENLTGDIAIQNRALAQKEK---DIQNMEKTIQDLNTEVARLKTNAAEHNQKT 3066 Query: 999 QSPDYTEQYINE-INKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKL 1057 + D T N+ I+KLN +KQ E+ L K + A ++ + D LAQ ++ Sbjct: 3067 IAKDATLTAKNDQISKLNDQIKQLRAEVTKL--KSDAADLNQATTSKDIV--LAQRMEEI 3122 Query: 1058 ENMEEEMQRVSKQLLDSK-----QHNEELQIL---VREQDDQIKELKETKLTFEMNIPKT 1109 + EM ++K L D++ Q+ +E+ L VR D+ +LK+ + + + Sbjct: 3123 NGLRNEMVELNKAL-DTRDTTFLQNTDEINRLKENVRRLGDETTKLKKDTVKLKEDSKSW 3181 Query: 1110 EGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQ 1169 E + E ++ +N+ L ++ E + L+++ L +L Sbjct: 3182 EETVKQRQTE-INKLNDNIKNLQEEIKRKEALLATRQGEI-----NALKDEIVGLKKDLA 3235 Query: 1170 ECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISS--- 1226 E K QL++ + EL ++ I ++ LE+L E L V L + Sbjct: 3236 E---KDAQLKSRDGELGKF----RKSIAAKETALERLEKEKTALREKVEHLEGEVGRRRR 3288 Query: 1227 AVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKI 1286 ++D R +I EL A R D K A E+ +++ +E + Sbjct: 3289 SLDLRADKILELTNSESAAR-LDLDKQR--------ARNKSLEETNTGLRNRAAKEGGSL 3339 Query: 1287 VTM-EQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXX 1345 + ++VT L +L +KE L +L+++ + I L + E Sbjct: 3340 GRLGDEVTKLSRQLLEKENDLASLRDECDGLQTDIHNLTRALAAE----GANVSQRDEQI 3395 Query: 1346 XXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLEL 1405 +L T + Q IN +QL ++ + Sbjct: 3396 ALLKQELTTRQAALDAKQAA----INTLESQLTEAQQAYDILASSNTTSQEELARSAAAT 3451 Query: 1406 THQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEK-ESELAILRL 1464 +L ++EI E +T N++ + Q+ + EKRI+ L E SE + R+ Sbjct: 3452 QARLLACEAEIASLRSE----ITNLNEDITAKKTQIADNEKRIDTLLREAGTSEAQLARM 3507 Query: 1465 KMHENANHYETMQKESEIERVKLIEELNVKITESVS 1500 KM +Q+E E ++ +L++E ++ ++ + Sbjct: 3508 KM-----TIAELQEEQENQQ-RLLDEYQSRLAQAAT 3537 Score = 37.1 bits (82), Expect = 4.0 Identities = 98/549 (17%), Positives = 216/549 (39%), Gaps = 47/549 (8%) Query: 143 DVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXX 202 D+ +L ++++ +N + L + M TI + + +KD+ I K T Sbjct: 2953 DIDNLKGSVQKLENKAATLAEEKAQMGQTIGAHETSLLKKDEDI----KKLTANIQRLTA 3008 Query: 203 XXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRI-SSLEEANKLLE 261 E+ + +Q +A + + ++ ++D+ ++ R+ ++ E N+ Sbjct: 3009 EANDLKKGIENLTGDIA-IQNRALAQKEKDIQNMEKTIQDLNTEVARLKTNAAEHNQKTI 3067 Query: 262 AARFEISLEH---SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEI 318 A ++ ++ SKL +++Q L + + +EE L Sbjct: 3068 AKDATLTAKNDQISKLNDQIKQLRAEVTKLKSDAADLNQATTSKDIVLAQRMEEINGLR- 3126 Query: 319 ANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNT 378 M EL K ++ + Q L+ + +G E+ + + K KS T Sbjct: 3127 NEMVELNKALDTRDTTFLQNTDEINRLKENVRRLGDETTKLKKDTVKLKE--DSKSWEET 3184 Query: 379 ASKMKSPWSQLSS--ETLNQDTDKK-----INKNEIAKLEMVIQSLNKDLVDKEYVISEK 431 + ++ ++L+ + L ++ +K + EI L+ I L KDL +K+ + + Sbjct: 3185 VKQRQTEINKLNDNIKNLQEEIKRKEALLATRQGEINALKDEIVGLKKDLAEKDAQLKSR 3244 Query: 432 DTXXXXXXXXXXGKDTLIAQLQLEHQ------QHMEGPSLIHVGTNTEDVNEIAKVQEQL 485 D K+T + +L+ E +H+EG VG ++ + + L Sbjct: 3245 DGELGKFRKSIAAKETALERLEKEKTALREKVEHLEG----EVGRRRRSLD--LRADKIL 3298 Query: 486 KQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTID 545 + ++ +++ + KS EE T L + ++ ++ +Q+ + + Sbjct: 3299 ELTNSESAARLDLDKQRARNKSLEETNTGLRNRAAKEGGSLGRLGDEVTKLSRQLLEKEN 3358 Query: 546 NFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEM 605 + + + D E L ++H+L++ +A E N+ S R + + K+ + Sbjct: 3359 DLASLRD---ECDGLQTDIHNLTRALA---AEGANV--------SQRDEQIALLKQELTT 3404 Query: 606 ENLA-ETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLA-DISQLQSDQVCSEIKSVH 663 A + + AI+ LESQ + Q IL +++LA + Q+ + E + Sbjct: 3405 RQAALDAKQAAINTLESQLTEAQQAYDILASSNTTSQEELARSAAATQARLLACEAEIAS 3464 Query: 664 LEEQIDALS 672 L +I L+ Sbjct: 3465 LRSEITNLN 3473 >UniRef50_Q8MSS1 Cluster: Protein lava lamp; n=1; Drosophila melanogaster|Rep: Protein lava lamp - Drosophila melanogaster (Fruit fly) Length = 2779 Score = 135 bits (327), Expect = 8e-30 Identities = 286/1545 (18%), Positives = 623/1545 (40%), Gaps = 117/1545 (7%) Query: 99 KQKEILMEKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNAL 158 + K + + ++ K L ++ + R GDV+ L + EK Sbjct: 87 RHKSSMSDSMESLKTLGQKLTVLKTRSGDSSTPLVSPTKDSDPGDVSLLQTSGSEK---- 142 Query: 159 SVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQM 218 +L + + + L Q K + ++ K+ + + Sbjct: 143 -LLMLTQRTEQNRALLEQRKRDLAKSLLSVKSNIGHQTTAELGSSMTDLRHAASVSNPPV 201 Query: 219 TKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISL-EHSKLAQE 277 ++ + + +EA+ ++ + ++++ L++ + E L + +KL + Sbjct: 202 SR-HRSALDLEAQGQEAVDESRVKLLRSRMKLTELKQGRQEQELNELRTELAKRAKLIER 260 Query: 278 LE-QXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNC 336 LE L + + + E+ +++E L+ + L +++ LE++N Sbjct: 261 LELSGAELQRTLTQRNEELEQLRVVQAEEDSLKVQENSRLQ-GEVLVLRERLAELENVND 319 Query: 337 QIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQ 396 + T EL+ +L T + + ++ K+ R+ S+ +Q+S+E Q Sbjct: 320 LLETTRCELQEELTTARERQRNLELEQEQ------EKASRSPQSEAAHTDAQVSAELAKQ 373 Query: 397 DTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQL-QLE 455 + N++A L+ + L + + + + + T + T+ AQL +L+ Sbjct: 374 LQELT---NQLADLQATNEELRQQVAAQAKL---QVTDEIVSQRLEELEATIAAQLLELQ 427 Query: 456 HQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQEL--NDEIKDVNVKDLIEKL---KSAEE 510 Q+ + T ++N + L+++L + K + ++D E K +E Sbjct: 428 EQKSAMAAQNEELAEKTTELNVLNVNLRLLEEKLAQSSRSKPLFLEDHSEDSAASKQMQE 487 Query: 511 QITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQK 570 + QL ++D NK IK+K LK KQ +K + F D +++ L + L Q+ Sbjct: 488 DLQQLKLKLDETNKANIKLK----LKCKQAEKKLQKFQS-QDGQQQLASLLADNEELQQR 542 Query: 571 VAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQEL 630 +A LE+EKG QL M E D + E+ +L+ I LLE QK +L Q L Sbjct: 543 IAVLEDEKGQWQL-------ANMQEDDRQPEQ-STESNNPLQLETIRLLEEQKLELQQAL 594 Query: 631 HILQQKYDEVED-KLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDK 689 L E ++ + L+ +EQ ++ + + + ++ Sbjct: 595 EALLSSSSSAESIEIVERHHLECLGQRRPASEGDAQEQKQVHPPGPSHVSELTQTEQTEE 654 Query: 690 EQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQT 749 E G + +L+ + QE ++ DKLE++SAE + +L A++ E S +Q Sbjct: 655 EDSSG------ETLSQLRERLELFTQERGEVLDKLEQLSAENL-QLQARL-EESSSSLQ- 705 Query: 750 QFGIDAKIQERDLYIE-NIESELSKYKSRICRLEESIAVME--DRRYSLERKADQLGSYL 806 + + +E+DL + S LS+ S + R E +A ++ + L K ++ S L Sbjct: 706 ---LLQREREKDLISSTSTSSNLSQELSSMQRSSEVVATLDAGEGGPVLFEKCEKSLSKL 762 Query: 807 QEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQ 866 + +AY + ++ + N L + QL E+ H+ KE + + + Sbjct: 763 NSELEAYRKANDRQAKF-NVSKKLAKEAKNCHTQLSELLHKVKEASTAVETVTVVETVVA 821 Query: 867 ISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIE 926 ++ + + A +L ++ ++ + +L +L + E IV + E Sbjct: 822 VTAPNGKALAEYEQLNAQNAEL-KAVISRLRQELDELRESYPET--EAPLAIVGSDSQRE 878 Query: 927 DLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNL 986 D ++ +Q+E A + ++ E+ ++ + +L E + + + +L ++ Sbjct: 879 DEILQLQSQLEDARSLQAEQRQQIEEQVDQIKELRQTEAEQLQLVARQSAEITQL-QLQS 937 Query: 987 ELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDY 1046 E D+ + ++ EQ +L A + + E+ L + + + VS+ Sbjct: 938 EQFDQLLNSKEMSHEKQLEQQTRIRRELEARAESLEGELSILQTLVAEQKQQLIESVSES 997 Query: 1047 ESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQI---LVREQDDQIKELKETKLTFE 1103 E L +L++ +EE++ + + D Q E L++ LV +Q ++ +ET Sbjct: 998 EHALNLKMLELQSAQEELREL-RAKEDPDQLREALRVSKSLVAQQVRELTSSQETVDALN 1056 Query: 1104 MNIPKTEGMIIS---------STIEPMSDDANNV-----DXXXXXXXXXXXXLKVQEEEE 1149 I + +G+ + E + A N+ D ++QE++E Sbjct: 1057 QQIQEYQGLEHAHKEEQFKNRELREKLKKYALNLKKRTQDNADLEQKVQELTSQLQEQQE 1116 Query: 1150 FIQERSVLQEQSAKLNTELQECYTKIIQL-ETLNTELTGHDVVNQEQINQLKSKL---EQ 1205 ++++ ++ + N +++ ++ +L E L ++ ++ N++ + QLK ++ EQ Sbjct: 1117 LVKQKEEVEREPIVDNHRVEQLQQQVSKLNEDLKAKI-HLNLENRDALRQLKQQIQEQEQ 1175 Query: 1206 LNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQRE--ADFQKTEHELRVQLSA 1263 L E D L + + + E+ +L +++ RE + Q+ H L +++ Sbjct: 1176 LIQERDAELQDANLVSKELRRERQEADQEVFQLGQENSRLREEISKLQEEIHNLGQRVNE 1235 Query: 1264 FESKYEQLLDSVQSSTQ--EETNKIVTMEQVT--SLQNKLQDKEEHLRNLQEKYADVINQ 1319 + E L +++ ++ E++ +++ + T SLQ +LQ ++ + E + Sbjct: 1236 EPTAVEDLRRQLEAKSKKFEKSKELIKLRNATIQSLQRELQQLQQDQDSEVEHVRNARAA 1295 Query: 1320 IEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKK 1379 E LR E + E A D S++ ++ QS E+ Q+ + Sbjct: 1296 HEQLRLEKDAEITALRQEILKLERSRAAGEGDDTITKTSHQLLESQS--QQQAESLQVAE 1353 Query: 1380 SSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQ 1439 + ++ Q L + + +T+ + E ++ Sbjct: 1354 -------------RELQQLRVQLTAAQEQHALLAQQYASDKANFEMTIARLETLHEGIQA 1400 Query: 1440 QLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESV 1499 +L E IE L + +EL + E A Q S+ ++V+++E+ ++ E Sbjct: 1401 KLQEDASYIESLE-AQNTELQARSAALEEQAASQANQQAASQ-DKVQILEQ---QLKEQR 1455 Query: 1500 SLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEIT--NLQNMVRASSSKIQKH 1557 +Q + ++ L+E + + + A +++++E++T E + L + S + KH Sbjct: 1456 EQEEQKRQQDQQLQERFYELGQREQA-QSRQLELLTSEAEESRQQLAGLRTEYESLLAKH 1514 Query: 1558 VSFASDTKQGRDEQLDNTMNKELLDAVPRAELDLAMYMLH-QRDV 1601 S + T Q EQ+ + +EL + R +LD+ LH QR V Sbjct: 1515 -SQLTATAQAEREQMSSHSQEELAEL--RQQLDVKEADLHRQRQV 1556 Score = 118 bits (284), Expect = 1e-24 Identities = 196/984 (19%), Positives = 419/984 (42%), Gaps = 69/984 (7%) Query: 148 SNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNK-----ATTXXXXXXXX 202 +N + K N L + K T + +L K+ E +E A T Sbjct: 772 ANDRQAKFNVSKKLAKEAKNCHTQLSELLHKVKEASTAVETVTVVETVVAVTAPNGKALA 831 Query: 203 XXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEA 262 + K ++++++ + + E + L + S R + + LE Sbjct: 832 EYEQLNAQNAELKAVISRLRQELDELRESYP-ETEAPLAIVGSDSQREDEILQLQSQLED 890 Query: 263 ARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMT 322 AR + + ++ ++++Q +A+QS E + + +++ + ++ N Sbjct: 891 ARSLQAEQRQQIEEQVDQIKELRQTEAEQLQLVARQSAEIT---QLQLQSEQFDQLLNSK 947 Query: 323 ELT--KKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTAS 380 E++ K++E + ++ + LE +L+ + T A S S + Sbjct: 948 EMSHEKQLEQQTRIRRELEARAESLEGELSILQT-LVAEQKQQLIESVSESEHALNLKML 1006 Query: 381 KMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXX 440 +++S +L +D D+ ++K +V Q + + +E V + Sbjct: 1007 ELQSAQEELRELRAKEDPDQLREALRVSK-SLVAQQVRELTSSQETVDALNQQIQEYQGL 1065 Query: 441 XXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQE-----QLKQELNDEIKD 495 K+ +L + +L + D+ + KVQE Q +QEL + ++ Sbjct: 1066 EHAHKEEQFKNRELREKLKKYALNLKKRTQDNADLEQ--KVQELTSQLQEQQELVKQKEE 1123 Query: 496 VNVKDLIE--KLKSAEEQITQLNDEIDAA-NKNMIKVKSNHKLK--LKQMQKTI-DNFSK 549 V + +++ +++ ++Q+++LN+++ A + N+ + +LK +++ ++ I + ++ Sbjct: 1124 VEREPIVDNHRVEQLQQQVSKLNEDLKAKIHLNLENRDALRQLKQQIQEQEQLIQERDAE 1183 Query: 550 VSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLA 609 + D+N L E Q+V +L +E L+ + S E + + E A Sbjct: 1184 LQDANLVSKELRRERQEADQEVFQLGQENSRLREEI----SKLQEEIHNLGQRVNEEPTA 1239 Query: 610 ETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVH----LE 665 L+ +S+KF+ +EL ++ + ++ ++ QLQ DQ SE++ V Sbjct: 1240 VEDLRRQLEAKSKKFEKSKEL--IKLRNATIQSLQRELQQLQQDQD-SEVEHVRNARAAH 1296 Query: 666 EQIDALSASKKELALVIENLKLDKEQLYGTIKD---------LENDKEDIMNKLQNYIQE 716 EQ+ L + AL E LKL++ + G D LE+ + LQ +E Sbjct: 1297 EQL-RLEKDAEITALRQEILKLERSRAAGEGDDTITKTSHQLLESQSQQQAESLQVAERE 1355 Query: 717 NMDLTDKLEKMSAEKISELLA------KINHEEQ-SKIQTQF-GIDAKIQERDLYIENIE 768 L +++ +A++ LLA K N E ++++T GI AK+QE YIE++E Sbjct: 1356 LQQL--RVQLTAAQEQHALLAQQYASDKANFEMTIARLETLHEGIQAKLQEDASYIESLE 1413 Query: 769 SELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLA 828 ++ ++ ++R LEE A +++ + + K L L+E+++ + Q+ +L R Sbjct: 1414 AQNTELQARSAALEEQAASQANQQAASQDKVQILEQQLKEQREQEEQKRQQDQQLQERFY 1473 Query: 829 VLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDL 888 L ++ +QL + E +E +++ L E ++L S + A E+ + Sbjct: 1474 ELGQREQAQSRQLELLTSEAEESRQQLAGLRTEYESLLAKHSQLTA--TAQAEREQMSSH 1531 Query: 889 AESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNE 948 ++ E + + QL E++L R + + K E+++LE + N+ +E A + + L + Sbjct: 1532 SQEELAELRQQLDVKEADLHRQRQVYDAKLAAKATELDELECDLNSHVERAAAETRELCQ 1591 Query: 949 KYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYI 1008 + E++ E V Q +LQ LN +E+ + + + V + Q D EQ + Sbjct: 1592 QLERSQELVAQRTEELQ-------RLNEEFQEVER-ERSTLSREVTLLRLQH-DSAEQDV 1642 Query: 1009 NEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVS 1068 E+ +L Q E+ L +I+ ++ + + ++A+ T +N ++ + Sbjct: 1643 LELQELRMQAMQDKTEMDNLRTQIDALCANHSQELQALQQRIAELDTLGQNQTDDQVYIE 1702 Query: 1069 KQLLDSKQHNEELQI-LVREQDDQ 1091 + + ELQ L R+Q Q Sbjct: 1703 TENKRLAEQLSELQAQLARQQHQQ 1726 Score = 95.5 bits (227), Expect = 1e-17 Identities = 183/887 (20%), Positives = 384/887 (43%), Gaps = 101/887 (11%) Query: 455 EHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQ 514 E E P I VG++++ +EI ++Q QL ++ + + E+ + EEQ+ Q Sbjct: 859 ESYPETEAPLAI-VGSDSQREDEILQLQSQL-----EDARSLQA----EQRQQIEEQVDQ 908 Query: 515 LNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSN-----KEIVRLTEELHHLSQ 569 + E+ +++ + ++ Q+Q + F ++ +S K++ + T L Sbjct: 909 IK-ELRQTEAEQLQLVARQSAEITQLQLQSEQFDQLLNSKEMSHEKQLEQQTRIRRELEA 967 Query: 570 KVAELEEEKGNLQLHLVDYDSGRMIES------DVYKKMIEMENLAET--RLKAISLLES 621 + LE E LQ LV ++IES + KM+E+++ E L+A + Sbjct: 968 RAESLEGELSILQT-LVAEQKQQLIESVSESEHALNLKMLELQSAQEELRELRAKEDPDQ 1026 Query: 622 QKFDLVQELHILQQKYDEVEDKLADISQL-QSDQVCSEIKSVHLEEQID--ALSASKKEL 678 + L ++ Q+ E+ + L Q Q ++ H EEQ L K+ Sbjct: 1027 LREALRVSKSLVAQQVRELTSSQETVDALNQQIQEYQGLEHAHKEEQFKNRELREKLKKY 1086 Query: 679 ALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAK 738 AL ++ D L +++L + ++ ++ +E ++ ++ E++ + ++K Sbjct: 1087 ALNLKKRTQDNADLEQKVQELTSQLQEQQELVKQ--KEEVEREPIVDNHRVEQLQQQVSK 1144 Query: 739 INHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERK 798 +N + ++KI ++ + R L + I+ + + R L+++ V ++ R + Sbjct: 1145 LNEDLKAKIH--LNLENRDALRQLK-QQIQEQEQLIQERDAELQDANLVSKELRRERQEA 1201 Query: 799 ADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQIL 858 ++ QE + E + ++E+ N + + VE ++E ++K+ +K +++ Sbjct: 1202 DQEVFQLGQENSRLREEISKLQEEIHNLGQRVNEEPTAVEDLRRQLEAKSKKFEKSKELI 1261 Query: 859 LEEN---QNLQISLSDMQQHYNALVEKANRTDLA--------ESESTKYQTQLRDLESNL 907 N Q+LQ L +QQ ++ VE A ++E T + ++ LE + Sbjct: 1262 KLRNATIQSLQRELQQLQQDQDSEVEHVRNARAAHEQLRLEKDAEITALRQEILKLERSR 1321 Query: 908 KR------ITH-EHQTLIVQKKKEIEDLEI------EFNTQIESAIRDKKVLNEKY---E 951 IT HQ L Q +++ E L++ + Q+ +A +L ++Y + Sbjct: 1322 AAGEGDDTITKTSHQLLESQSQQQAESLQVAERELQQLRVQLTAAQEQHALLAQQYASDK 1381 Query: 952 KNIEY-VTQLE-------AQLQEYKNNIENLNMNVEELNKMNLELIDKHVQK--QQTQSP 1001 N E + +LE A+LQE + IE+L EL + L ++ + QQ S Sbjct: 1382 ANFEMTIARLETLHEGIQAKLQEDASYIESLEAQNTELQARSAALEEQAASQANQQAASQ 1441 Query: 1002 DYT---EQYINEINKLNALLKQKDEEI------IALNQKINNAQVSYM-SMVSDYESKLA 1051 D EQ + E + +Q+D+++ + ++ + Q+ + S + +LA Sbjct: 1442 DKVQILEQQLKEQREQEEQKRQQDQQLQERFYELGQREQAQSRQLELLTSEAEESRQQLA 1501 Query: 1052 QFTTKLENM-EEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTE 1110 T+ E++ + Q + + +Q + Q + E Q+ ++KE L + + + Sbjct: 1502 GLRTEYESLLAKHSQLTATAQAEREQMSSHSQEELAELRQQL-DVKEADLHRQRQVYDAK 1560 Query: 1111 GMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQE 1170 ++ ++ + D N+ +++ +E + +R+ E+ +LN E QE Sbjct: 1561 LAAKATELDELECDLNS-HVERAAAETRELCQQLERSQELVAQRT---EELQRLNEEFQE 1616 Query: 1171 CYTKIIQLETLNTELT----GHDVVNQE--QINQLKSKLEQLNTENDNLLSTVAELRSSI 1224 + TL+ E+T HD Q+ ++ +L+ + Q TE DNL + + L ++ Sbjct: 1617 VER---ERSTLSREVTLLRLQHDSAEQDVLELQELRMQAMQDKTEMDNLRTQIDALCANH 1673 Query: 1225 SSAVDQRGFEIAELWKQHLAQREADFQ---KTEHE-LRVQLSAFESK 1267 S + IAEL L Q + D Q +TE++ L QLS +++ Sbjct: 1674 SQELQALQQRIAEL--DTLGQNQTDDQVYIETENKRLAEQLSELQAQ 1718 Score = 89.4 bits (212), Expect = 7e-16 Identities = 162/919 (17%), Positives = 386/919 (42%), Gaps = 57/919 (6%) Query: 318 IANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRN 377 +A +L + L+ + ++RQ EL V S S++ ++ +S Sbjct: 830 LAEYEQLNAQNAELKAVISRLRQELDELRESYPETEAPLAIVGSDSQREDEILQLQSQLE 889 Query: 378 TASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXX 437 A +++ Q E ++Q K++ + E +L++V + + + + + SE+ Sbjct: 890 DARSLQAEQRQQIEEQVDQI--KELRQTEAEQLQLVARQSAE--ITQLQLQSEQFDQLLN 945 Query: 438 XXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVN 497 K L Q ++ + SL G + +A+ ++QL + +++ +N Sbjct: 946 SKEMSHEKQ-LEQQTRIRRELEARAESL--EGELSILQTLVAEQKQQLIESVSESEHALN 1002 Query: 498 VKDLIEKLKSAEEQITQLNDEIDAAN-KNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKE 556 +K L +L+SA+E++ +L + D + ++V + L +Q+++ + V N++ Sbjct: 1003 LKML--ELQSAQEELRELRAKEDPDQLREALRVSKS--LVAQQVRELTSSQETVDALNQQ 1058 Query: 557 IVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAI 616 I H ++ + E + L+ + ++ +D+ +K+ E+ + + + + + Sbjct: 1059 IQEYQGLEHAHKEEQFKNRELREKLKKYALNLKKRTQDNADLEQKVQELTSQLQEQQELV 1118 Query: 617 SLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKK 676 E + + + + H ++Q +V S+L D ++ + + L + Sbjct: 1119 KQKEEVEREPIVDNHRVEQLQQQV-------SKLNEDLKAKIHLNLENRDALRQLKQQIQ 1171 Query: 677 ELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELL 736 E +I+ + + K+L ++++ ++ QEN L +++ K+ E+I L Sbjct: 1172 EQEQLIQERDAELQDANLVSKELRRERQEADQEVFQLGQENSRLREEISKLQ-EEIHNLG 1230 Query: 737 AKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLE 796 ++N E + + ++AK ++ + E I+ + +S L++ + +D+ +E Sbjct: 1231 QRVNEEPTAVEDLRRQLEAKSKKFEKSKELIKLRNATIQSLQRELQQ---LQQDQDSEVE 1287 Query: 797 RKADQLGSYLQEKQKAYSEYTIQEDELVN--RLAVLMDHDRVVEKQLLEI-EHENKELQK 853 + ++ Q + + +E T E++ R + D + K ++ E ++++ + Sbjct: 1288 HVRNARAAHEQLRLEKDAEITALRQEILKLERSRAAGEGDDTITKTSHQLLESQSQQQAE 1347 Query: 854 KNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESEST--KYQTQLRDLESNLKRIT 911 Q+ E Q L++ L+ Q+ + AL+ + +D A E T + +T +++ L+ Sbjct: 1348 SLQVAERELQQLRVQLTAAQEQH-ALLAQQYASDKANFEMTIARLETLHEGIQAKLQEDA 1406 Query: 912 H-----EHQTLIVQKKKEIEDLEIEFNTQIESAIRDK-KVLNEKYEKNIEYVTQLEAQLQ 965 E Q +Q + + + ++A +DK ++L ++ ++ E Q Q Q Sbjct: 1407 SYIESLEAQNTELQARSAALEEQAASQANQQAASQDKVQILEQQLKEQREQEEQKRQQDQ 1466 Query: 966 EYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALL------- 1018 + + L E+ LEL+ ++ + Q +Y + + K + L Sbjct: 1467 QLQERFYELGQR-EQAQSRQLELLTSEAEESRQQLAGLRTEYESLLAKHSQLTATAQAER 1525 Query: 1019 ----KQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENME----EEMQRVSKQ 1070 EE+ L Q+++ + Y++KLA T+L+ +E ++R + + Sbjct: 1526 EQMSSHSQEELAELRQQLDVKEADLHRQRQVYDAKLAAKATELDELECDLNSHVERAAAE 1585 Query: 1071 LLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDX 1130 + Q E Q LV ++ ++++ L E F+ + + T+ + D+ D Sbjct: 1586 TRELCQQLERSQELVAQRTEELQRLNEE---FQEVERERSTLSREVTLLRLQHDSAEQDV 1642 Query: 1131 XXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDV 1190 +Q++ E R+ + A + ELQ +I +L+TL T V Sbjct: 1643 LELQELRMQA---MQDKTEMDNLRTQIDALCANHSQELQALQQRIAELDTLGQNQTDDQV 1699 Query: 1191 VNQEQINQLKSKLEQLNTE 1209 + + +L +L +L + Sbjct: 1700 YIETENKRLAEQLSELQAQ 1718 Score = 84.2 bits (199), Expect = 3e-14 Identities = 163/824 (19%), Positives = 339/824 (41%), Gaps = 84/824 (10%) Query: 498 VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEI 557 ++DL + E+ L ++ A N+N+ + + +L+L+Q ++ +S+ +++ Sbjct: 1786 IEDLQRNVSDLEKHAQDLETKLLARNQNLAE-QEERRLQLEQRLSEVERL--LSERTQQL 1842 Query: 558 VRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIES---DVYKKMIEMENLAETRLK 614 + + + ++A LE+ +D G E D +++ L +T Sbjct: 1843 ADI-QTANEERDRLAALEKLIQPAAAPTLDMFFGGQAEETVPDAVSHHLDL-GLPQTEPV 1900 Query: 615 AISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSAS 674 L++ +K L Q +Q++ + D D S +E +E L Sbjct: 1901 VEPLIQPKKAYLCQPKQEIQEQTAQTIDWGVDEDPWAS--AANEAPQTDVEH----LHTR 1954 Query: 675 KKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISE 734 +L L + N + K +L L ++ K + + + L+ E++ Sbjct: 1955 IAQLELQLSNAEQQKTELQTKAAKLMKRLKEYKTKATTTATPTVTVDNDLDSTIIEELKH 2014 Query: 735 LLAKINHEEQSK---IQTQFGIDA-KIQERDLYIENIESELSKYKSRICRLEESIAVMED 790 L ++ SK I Q ++ K+ +R + +++ K R + + + + Sbjct: 2015 QL-QLQESRLSKAEEISQQHALEKEKLAKRIDVLTAGNDRMAEMKER---QDMDVQMYQA 2070 Query: 791 RRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKE 850 R L+ K QL + + S ++ DE R+ L + + +Q+ E+E E Sbjct: 2071 RIRELQEKLSQLDQWGEPAATVSS--SLDGDEAA-RIESLQQEIQQLRQQVSELEDERTR 2127 Query: 851 LQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRI 910 Q + L + +Q + + + L ++ + E+ T+ Q++L L + + Sbjct: 2128 DQAELGALRQSSQGYDEAEDNQKLELQQLRQQESEL---EALRTRDQSELEALRQSCQG- 2183 Query: 911 THEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNN 970 H+ I +++ + LE++ Q+ AI + + L + + T+LEA Q + + Sbjct: 2184 -HDETVRIATLQQDNQQLELQ---QLRQAIIELETLRARDQ------TELEALRQSSQGH 2233 Query: 971 IENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQ 1030 E + +E+ + LEL +Q ++ +L AL + E+ AL Q Sbjct: 2234 DEAARIAIEQRDNQQLEL----------------QQLRQQLIELEALRARDQAELEALRQ 2277 Query: 1031 KINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDD 1090 Q+S + M S + ++AQ K + QR+ + + + + +IL + Q+ Sbjct: 2278 SCQGQQLS-VDMASRNDEQMAQLQEKESEIVHLKQRIEELMREDQTEKLVFEILTKNQEL 2336 Query: 1091 QIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEF 1150 Q+ ++ +L + E +S+ P DD V+ EEE Sbjct: 2337 QLLRMQVKQLEEDK-----EDQQVSAA--PPKDDGETVEKLKSLCQQLQQEKSDMEEELR 2389 Query: 1151 IQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTEN 1210 + VL S +L +++ ++QL+T N E+T ++ +I Q ++ + E Sbjct: 2390 VLNNHVLS--SLELEDRMKQT---LLQLDTKNIEIT--ELRRSLEILQSQNLGQNSAAEQ 2442 Query: 1211 DNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQ 1270 LS + + + V+Q+ E+A +W++HL+QREA F + QL + ++ Sbjct: 2443 IPDLSAINQQWEQL---VEQKCGEVASIWQEHLSQREAAF-------KAQLEEVTQQQQR 2492 Query: 1271 LLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYA 1314 L Q STQ E T + + +Q L+ +E + L+E+ A Sbjct: 2493 ELPQSQQSTQGE----ATSDIMQKMQKALETQEMEIVTLKEQLA 2532 Score = 79.4 bits (187), Expect = 8e-13 Identities = 265/1460 (18%), Positives = 578/1460 (39%), Gaps = 131/1460 (8%) Query: 152 KEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIE-AKNKATTXXXXXXXXXXXXXXXX 210 +E + L+ ++ I++T + + ++++ E E A N Sbjct: 963 RELEARAESLEGELSILQTLVAEQKQQLIESVSESEHALNLKMLELQSAQEELRELRAKE 1022 Query: 211 XEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLE 270 D ++ ++ ++ +A + Q + + + LE A+K + E+ + Sbjct: 1023 DPDQLREALRVSKSLVAQQVRELTSSQETVDALNQQIQEYQGLEHAHKEEQFKNRELREK 1082 Query: 271 HSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPS--CEEKTEIEEKGSLEIANMTELTKKI 328 K A L++ L Q E ++K E+E + ++ + +L +++ Sbjct: 1083 LKKYALNLKKRTQDNADLEQKVQELTSQLQEQQELVKQKEEVEREPIVDNHRVEQLQQQV 1142 Query: 329 ELL-EHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWS 387 L E L +I + LEN+ A + + ++ LI + + + S Sbjct: 1143 SKLNEDLKAKI---HLNLENRDAL-----RQLKQQIQEQEQLIQERDAELQDANLVS--K 1192 Query: 388 QLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDT 447 +L E D + E ++L I L +++ + ++E+ T + Sbjct: 1193 ELRRERQEADQEVFQLGQENSRLREEISKLQEEIHNLGQRVNEEPTAV----------ED 1242 Query: 448 LIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDV-NVKDLIEKLK 506 L QL+ + ++ + LI + T + + + +QL+Q+ + E++ V N + E+L+ Sbjct: 1243 LRRQLEAKSKKFEKSKELIKLRNAT--IQSLQRELQQLQQDQDSEVEHVRNARAAHEQLR 1300 Query: 507 SAEE-QITQLNDEIDAANKNMIK-------VKSNHKLKLKQMQKTIDNFSKVSDSNKEI- 557 ++ +IT L EI ++ K++H+L Q Q+ ++ +++ Sbjct: 1301 LEKDAEITALRQEILKLERSRAAGEGDDTITKTSHQLLESQSQQQAESLQVAERELQQLR 1360 Query: 558 VRLTEELHHLSQKVAELEEEKGNLQLHLVDYDS------GRMIESDVYKKMIEMENLAET 611 V+LT + + +K N ++ + ++ ++ E Y + +E +N T Sbjct: 1361 VQLTAAQEQHALLAQQYASDKANFEMTIARLETLHEGIQAKLQEDASYIESLEAQN---T 1417 Query: 612 RLKAISL-LESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDA 670 L+A S LE Q + Q K +E +L + + Q +Q + L+E+ Sbjct: 1418 ELQARSAALEEQAASQANQQAASQDKVQILEQQLKEQRE-QEEQ--KRQQDQQLQERFYE 1474 Query: 671 LSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAE 730 L ++ + +E L + E+ + L + E ++ K +++ S E Sbjct: 1475 LGQREQAQSRQLELLTSEAEESRQQLAGLRTEYESLLAKHSQLTATAQAEREQMSSHSQE 1534 Query: 731 KISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMED 790 +++EL +++ +E + + DAK+ + ++ +E +L+ + +E + A + Sbjct: 1535 ELAELRQQLDVKEADLHRQRQVYDAKLAAKATELDELECDLNSH------VERAAAETRE 1588 Query: 791 RRYSLERKADQLGSYLQEKQKAYSEYTIQEDE---LVNRLAVL-MDHDRVVEKQLLEIEH 846 LER + + +E Q+ E+ E E L + +L + HD E+ +LE++ Sbjct: 1589 LCQQLERSQELVAQRTEELQRLNEEFQEVERERSTLSREVTLLRLQHDSA-EQDVLELQE 1647 Query: 847 ENKE-LQKKNQILLEENQNLQISL--SDMQQHYNALVEKA--------NRTD---LAESE 892 + +Q K ++ +N QI ++ Q AL ++ N+TD E+E Sbjct: 1648 LRMQAMQDKTEM---DNLRTQIDALCANHSQELQALQQRIAELDTLGQNQTDDQVYIETE 1704 Query: 893 STKYQTQLRDLESNLKRITHE-----HQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLN 947 + + QL +L++ L R H+ H VQ ++ + F +A + Sbjct: 1705 NKRLAEQLSELQAQLARQQHQQQQQQHHHPAVQSQQHPPPASLFFGGDALAAPSPFDEIA 1764 Query: 948 EKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPD----- 1002 + + + IE+L NV +L K +L K + + Q + Sbjct: 1765 QPLR--VSSLAASAPPPISPPPTIEDLQRNVSDLEKHAQDLETKLLARNQNLAEQEERRL 1822 Query: 1003 YTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEE 1062 EQ ++E+ +L + Q+ +I N++ + + ++ + + E Sbjct: 1823 QLEQRLSEVERLLSERTQQLADIQTANEE-RDRLAALEKLIQPAAAPTLDMFFGGQAEET 1881 Query: 1063 EMQRVSKQL-LDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPM 1121 VS L L Q ++ L++ + + + K+ E + + Sbjct: 1882 VPDAVSHHLDLGLPQTEPVVEPLIQPKKAYLCQPKQE--IQEQTAQTIDWGVDEDPWASA 1939 Query: 1122 SDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLET- 1180 +++A D L++ E Q+++ LQ ++AKL L+E TK T Sbjct: 1940 ANEAPQTDVEHLHTRIAQLELQLSNAE---QQKTELQTKAAKLMKRLKEYKTKATTTATP 1996 Query: 1181 ---LNTELTG---HDVVNQEQINQLK-SKLEQLNTENDNLLSTVAELRSSISSAVDQRGF 1233 ++ +L ++ +Q Q+ + + SK E+++ ++ +A+ R + +A + R Sbjct: 1997 TVTVDNDLDSTIIEELKHQLQLQESRLSKAEEISQQHALEKEKLAK-RIDVLTAGNDRMA 2055 Query: 1234 EIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQ-V 1292 E+ E + +A + EL+ +LS + E S +E +I +++Q + Sbjct: 2056 EMKERQDMDVQMYQARIR----ELQEKLSQLDQWGEPAATVSSSLDGDEAARIESLQQEI 2111 Query: 1293 TSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDL 1352 L+ ++ + E+ R + + Q E ED + L Sbjct: 2112 QQLRQQVSELEDE-RTRDQAELGALRQSSQGYDEAEDNQ----KLELQQLRQQESELEAL 2166 Query: 1353 RTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELK 1412 RT +QS + QS ++E ++ + R E + L Q EL+ Sbjct: 2167 RTRDQSELEALRQSCQG-HDETVRIA-TLQQDNQQLELQQLRQAIIELETLRARDQTELE 2224 Query: 1413 DSEIYQKTHEYT--ITLTQRND---EFENVRQQLVEYEK-------RIEDLTYEKESELA 1460 + H+ I + QR++ E + +RQQL+E E +E L + + Sbjct: 2225 ALRQSSQGHDEAARIAIEQRDNQQLELQQLRQQLIELEALRARDQAELEALRQSCQGQQL 2284 Query: 1461 ILRLKMHENANHYETMQKESEIERVK-LIEELNVKITESVSLNKQVAELNKALEEEVAKT 1519 + + + + +KESEI +K IEEL ++ ++ L ++ N+ L+ + Sbjct: 2285 SVDMASRNDEQMAQLQEKESEIVHLKQRIEEL-MREDQTEKLVFEILTKNQELQLLRMQV 2343 Query: 1520 NEMQTALENQEIEIVTLNDE 1539 +++ E+Q++ D+ Sbjct: 2344 KQLEEDKEDQQVSAAPPKDD 2363 Score = 79.4 bits (187), Expect = 8e-13 Identities = 260/1440 (18%), Positives = 562/1440 (39%), Gaps = 135/1440 (9%) Query: 213 DTKQQMTKMQENFIAMEAEWKDEKQRLLKDIES-KDVRISSLEEANKLLEAARFEISLEH 271 + K + + + I + QR L+ ++ +D + + A E R E E Sbjct: 1248 EAKSKKFEKSKELIKLRNATIQSLQRELQQLQQDQDSEVEHVRNARAAHEQLRLEKDAEI 1307 Query: 272 SKLAQELE--QXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANM-TELTKKI 328 + L QE+ + + Q +E +++ E + E+ + +LT Sbjct: 1308 TALRQEILKLERSRAAGEGDDTITKTSHQLLESQSQQQAESLQVAERELQQLRVQLTAAQ 1367 Query: 329 ELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQ 388 E L Q E +A + T + + + ++ + I +NT + +S + Sbjct: 1368 EQHALLAQQYASDKANFEMTIARLETLHEGIQAKLQEDASYIESLEAQNTELQARS--AA 1425 Query: 389 LSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTL 448 L + +Q + +++++ LE Q L + +E + + Sbjct: 1426 LEEQAASQANQQAASQDKVQILE---QQLKEQREQEEQKRQQDQQLQERFYELGQREQAQ 1482 Query: 449 IAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSA 508 QL+L + E + G TE + +AK QL E + ++ + Sbjct: 1483 SRQLELLTSEAEESRQQL-AGLRTEYESLLAK-HSQLTATAQAEREQMS--------SHS 1532 Query: 509 EEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLS 568 +E++ +L ++D ++ + + + KL +D D N + R E L Sbjct: 1533 QEELAELRQQLDVKEADLHRQRQVYDAKLAAKATELDELE--CDLNSHVERAAAETRELC 1590 Query: 569 QKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQ 628 Q++ +E V ++ E++ L E +E ++ L + Sbjct: 1591 QQLERSQEL--------------------VAQRTEELQRLNEE----FQEVERERSTLSR 1626 Query: 629 ELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLD 688 E+ +L+ ++D E + ++ +L+ + + + +L QIDAL A+ + ++ + Sbjct: 1627 EVTLLRLQHDSAEQDVLELQELRMQAMQDKTEMDNLRTQIDALCANHSQELQALQQRIAE 1686 Query: 689 KEQLYGTIKDLENDKEDIMNKLQNYIQ-ENMDLTDKLEKMSAEKISELLAKINHEEQSK- 746 + L +N +D Q YI+ EN L ++L ++ A+ LA+ H++Q + Sbjct: 1687 LDTLG------QNQTDD-----QVYIETENKRLAEQLSELQAQ-----LARQQHQQQQQQ 1730 Query: 747 -----IQTQ---------FGIDAKIQER--DLYIENIE-SELSKYKSRICRLEESIAVME 789 +Q+Q FG DA D + + S L+ +I ++ Sbjct: 1731 HHHPAVQSQQHPPPASLFFGGDALAAPSPFDEIAQPLRVSSLAASAPPPISPPPTIEDLQ 1790 Query: 790 DRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENK 849 LE+ A L + L + + +E + +L RL+ + +QL +I+ N+ Sbjct: 1791 RNVSDLEKHAQDLETKLLARNQNLAEQEERRLQLEQRLSEVERLLSERTQQLADIQTANE 1850 Query: 850 ELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKR 909 E ++++ E + + + E+ + ++ S L E ++ Sbjct: 1851 E---RDRLAALEKLIQPAAAPTLDMFFGGQAEET----VPDAVSHHLDLGLPQTEPVVEP 1903 Query: 910 ITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKN 969 + + + Q K+EI++ + NE + ++E++ AQL+ + Sbjct: 1904 LIQPKKAYLCQPKQEIQEQTAQTIDWGVDEDPWASAANEAPQTDVEHLHTRIAQLELQLS 1963 Query: 970 NIENLNMNVE-ELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIAL 1028 N E ++ + K+ L + + T +P T N+++ + ++++ ++ Sbjct: 1964 NAEQQKTELQTKAAKLMKRLKEYKTKATTTATPTVTVD--NDLD--STIIEELKHQLQLQ 2019 Query: 1029 NQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVS-KQLLDSKQHNEELQILVRE 1087 +++ A+ + E KLA+ L + M + +Q +D + + ++ L +E Sbjct: 2020 ESRLSKAEEISQQHALEKE-KLAKRIDVLTAGNDRMAEMKERQDMDVQMYQARIREL-QE 2077 Query: 1088 QDDQIKELKETKLTFEMNIPKTEGMIISST---IEPMSDDANNVDXXXXXXXXXXXXLKV 1144 + Q+ + E T ++ E I S I+ + + ++ L+ Sbjct: 2078 KLSQLDQWGEPAATVSSSLDGDEAARIESLQQEIQQLRQQVSELEDERTRDQAELGALRQ 2137 Query: 1145 QEE--EEFIQERSVLQEQSAKLNTELQECYTKI-IQLETLNTELTGHD----VVNQEQIN 1197 + +E + + +Q + +EL+ T+ +LE L GHD + +Q N Sbjct: 2138 SSQGYDEAEDNQKLELQQLRQQESELEALRTRDQSELEALRQSCQGHDETVRIATLQQDN 2197 Query: 1198 QLKSKLEQLNTENDNLLSTVAELRSSISSA--VDQRGFEIAELWKQHLAQREADFQKTEH 1255 Q + +L+QL L + A ++ + + Q E A + + ++ + Q+ Sbjct: 2198 Q-QLELQQLRQAIIELETLRARDQTELEALRQSSQGHDEAARIAIEQRDNQQLELQQLRQ 2256 Query: 1256 ELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYAD 1315 +L ++L A ++ + L++++ S Q + + + +LQ+KE + +L+++ Sbjct: 2257 QL-IELEALRARDQAELEALRQSCQGQQLSVDMASRNDEQMAQLQEKESEIVHLKQR--- 2312 Query: 1316 VINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENA 1375 IE L E + EK+ F E++ +Q+ + E Sbjct: 2313 ----IEELMREDQTEKLVFEILTKNQELQLLRMQVKQLEEDKEDQQVSAAPPKDDGETVE 2368 Query: 1376 QLKKSSXXXXXXXXXXXXRVNDAEAKVLE-LTHQLELKDSEIYQKTHEYTITLTQRNDEF 1434 +LK + VL L + +K + + T IT +R+ E Sbjct: 2369 KLKSLCQQLQQEKSDMEEELRVLNNHVLSSLELEDRMKQTLLQLDTKNIEITELRRSLEI 2428 Query: 1435 ---ENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEEL 1491 +N+ Q ++I DL+ + ++ K E A+ ++ + E +EE+ Sbjct: 2429 LQSQNLGQNSAA--EQIPDLSAINQQWEQLVEQKCGEVASIWQEHLSQREAAFKAQLEEV 2486 Query: 1492 NVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEIT-NLQNMVRAS 1550 + + ++Q + +A + + K MQ ALE QE+EIVTL +++ R + Sbjct: 2487 TQQQQRELPQSQQSTQ-GEATSDIMQK---MQKALETQEMEIVTLKEQLAIRSAEYARLA 2542 Query: 1551 SS----KIQKHVSFA----SDTKQGRDEQLDNTMNKELLDAVPRAELDLAMYMLHQRDVR 1602 + ++Q + + T T N+ L + V +A+LD A+ MLHQRD+R Sbjct: 2543 AQYDPFRLQNRGGASGGNPASTTVSAGGPPSLTANEPLPEYVLKADLDYALMMLHQRDMR 2602 >UniRef50_A0CKT9 Cluster: Chromosome undetermined scaffold_20, whole genome shotgun sequence; n=2; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_20, whole genome shotgun sequence - Paramecium tetraurelia Length = 932 Score = 135 bits (326), Expect = 1e-29 Identities = 200/940 (21%), Positives = 411/940 (43%), Gaps = 100/940 (10%) Query: 628 QELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDAL-SASKKELALVIENLK 686 +EL I + KY+ ++ + ++QL+ Q + ++ + ++ + S + ++ N Sbjct: 38 KELEIWKDKYETLQKRWDTLNQLKEKQDGKTKQDINDSKTLNQVPKTSGHQQTSLLPNT- 96 Query: 687 LDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSK 746 +K+Q ++ L + K + IQE L+D+ EK S I +I +++ S+ Sbjct: 97 -EKQQFQILVQQLNEQ----IAKQKKQIQE---LSDRNEKHS---IDNKKLEIENKKYSE 145 Query: 747 IQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYL 806 QF + + D ++ +Y+ + + ++I M+ + S E++ ++L Sbjct: 146 QLNQFRKTSHHKFND-------QQMLQYEENVQKFIQTIDEMKQEKNSFEKQIEKLTKEN 198 Query: 807 QEKQKAYSEY--TIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQN 864 Q Q++ E +IQE + + H + Q+ E+ +N +L+K + L +++Q+ Sbjct: 199 QSLQQSNDELKKSIQEHDKGQQ------HKNQFQLQISELGLKNNQLEKLVKDLEKQSQH 252 Query: 865 LQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKE 924 Q LS +Q + +K +++ +YQ +L +L + L+ + +E Q + Q + Sbjct: 253 QQ-DLS--KQTAKQMDDKQQEIQSLQNKVQEYQKELSNL-NQLQDVYNEQQLQLQQLAQV 308 Query: 925 IEDLE--IEFNTQIESAIRDKKVLNEKYEKNIEYVTQLE--------------AQLQEYK 968 I++LE + +T +S + K ++ KY+ + T L+ +QL++ K Sbjct: 309 IQELEGKLSESTNPQSYESEIKQISIKYDDLYQQYTDLQTQDIMKQEWLNLQKSQLEDLK 368 Query: 969 NNIENLNMNVEELNKMNLELIDK-HVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIA 1027 + L+ +EEL K N LI + +QK +T+ + Q ++IN ++ K+EEI Sbjct: 369 QENDQLSQKIEELQKQNDVLIGQIEIQKDETKLS--SSQLQDQINSYEHIVSDKNEEIHK 426 Query: 1028 LNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQ-HNEELQILVR 1086 L ++ + S + DYE K+ Q T+ E +E E SK ++ + N EL+ + Sbjct: 427 LKVELTKQKCSLKN--DDYEEKIQQLKTQYEKLESE----SKMKIEWMEIQNTELEETIN 480 Query: 1087 EQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKV-- 1144 E + +I+ E N P+ + I+ E + V+ +K Sbjct: 481 EYEKKIQNFVEQLNQINKNNPEDQSQKITELKEHLQQYELIVNNKNFEIDELKKQIKEIN 540 Query: 1145 --QEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSK 1202 Q +E+F ++ L+ Q KL TE Q Q + + E QEQIN L ++ Sbjct: 541 QKQNDEDFEKKYLNLKTQFEKLETENQMKQ----QWQNIQEE------EQQEQINTLNAQ 590 Query: 1203 LEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQK--TEHELRVQ 1260 + +LN + ++ + +L++ + VD+ ++++ +QHL + F + LR Sbjct: 591 IVELNDQLNSTQNLYLKLQTDLQQEVDKNE-QLSKQSQQHLLDIQNSFNSGNIRNALRKS 649 Query: 1261 LSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQI 1320 + ES +E + +++ ++ N + E++ +L +L + EE+ NLQ++ ++ Q Sbjct: 650 IKKEES-FEDEANIKKNADEKCINDL--KEKIQTLNEELGEYEENQSNLQQQIGELTEQK 706 Query: 1321 EILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLR----------TENQSYKQMQEQSILNI 1370 ++ + E E + DL ENQ Q E +L + Sbjct: 707 NKIQLQYE-EMYNYYSKAYDQIQNFITQVEDLNKIILDKENQIVENQYQIQQLEDQLLQM 765 Query: 1371 NEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLE-LKDSEIYQKTHEYTITLTQ 1429 NE N + R + E + L QLE D E YQK ++ + Sbjct: 766 NEINKDAYTENQDINQMKAFYEQRFLEQETLIQNLQQQLEQTSDQEYYQKMNQ----ILH 821 Query: 1430 RNDEFENVR----QQLVEYEKRIEDLTYEKESELAIL-RLKMHENANHYETMQKESEIER 1484 N+E + +R ++L + ++ IE+L + S+ + + E E + K + ++ Sbjct: 822 ENEELKQLRSENQEELNKKDQLIEELQMQMLSQSQVTGSSDLQERKRRQELLDKVKD-DK 880 Query: 1485 VKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQT 1524 + E N ++ + + A +L+ + + QT Sbjct: 881 SEKSESSNEQLVKKIGKKTSGASAKLSLKLDYNQDGSKQT 920 Score = 111 bits (268), Expect = 1e-22 Identities = 197/882 (22%), Positives = 394/882 (44%), Gaps = 96/882 (10%) Query: 484 QLKQELNDEIKDVNV-KDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQK 542 + K E K++ + KD E L+ + + QL ++ D K I N L Q+ K Sbjct: 28 RFKFEKEASSKELEIWKDKYETLQKRWDTLNQLKEKQDGKTKQDI----NDSKTLNQVPK 83 Query: 543 TIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKM 602 T + N E + + L++++A+ +K +Q L D + I++ K Sbjct: 84 TSGHQQTSLLPNTEKQQFQILVQQLNEQIAK---QKKQIQ-ELSDRNEKHSIDN----KK 135 Query: 603 IEMENLAET-RLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKS 661 +E+EN + +L KF+ Q L Q + V+ + I +++ ++ E + Sbjct: 136 LEIENKKYSEQLNQFRKTSHHKFNDQQML----QYEENVQKFIQTIDEMKQEKNSFEKQI 191 Query: 662 VHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLT 721 L ++ +L S EL I+ + DK Q + L+ + + N N +++ L Sbjct: 192 EKLTKENQSLQQSNDELKKSIQ--EHDKGQQHKNQFQLQISELGLKN---NQLEK---LV 243 Query: 722 DKLEKMSAEK--ISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRIC 779 LEK S + +S+ AK ++Q +IQ+ + K+QE + N+ Y + Sbjct: 244 KDLEKQSQHQQDLSKQTAKQMDDKQQEIQS---LQNKVQEYQKELSNLNQLQDVYNEQQL 300 Query: 780 RLEESIAVMEDRRYSLERKADQLGSYLQEKQKA--YSEYTIQEDELVNRLAVLMDHDRVV 837 +L++ V+++ L + + KQ + Y + Q +L + + + + Sbjct: 301 QLQQLAQVIQELEGKLSESTNPQSYESEIKQISIKYDDLYQQYTDLQTQDIMKQEWLNLQ 360 Query: 838 EKQLLEIEHEN-------KELQKKNQILLEE----NQNLQISLSDMQQHYNA----LVEK 882 + QL +++ EN +ELQK+N +L+ + ++S S +Q N+ + +K Sbjct: 361 KSQLEDLKQENDQLSQKIEELQKQNDVLIGQIEIQKDETKLSSSQLQDQINSYEHIVSDK 420 Query: 883 ANRTDLAESESTKYQTQLR--DLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAI 940 + E TK + L+ D E ++++ +++ L + K +IE +EI+ NT++E I Sbjct: 421 NEEIHKLKVELTKQKCSLKNDDYEEKIQQLKTQYEKLESESKMKIEWMEIQ-NTELEETI 479 Query: 941 RD--KKV------LNEKYEKNIE----YVTQLEAQLQEYKNNIENLNMNVEELNKMNLEL 988 + KK+ LN+ + N E +T+L+ LQ+Y+ + N N ++EL K E+ Sbjct: 480 NEYEKKIQNFVEQLNQINKNNPEDQSQKITELKEHLQQYELIVNNKNFEIDELKKQIKEI 539 Query: 989 IDKHVQKQQTQSPDYTEQYIN---EINKLNA--LLKQKDEEIIALNQ--KIN--NAQVSY 1039 Q+ D+ ++Y+N + KL +KQ+ + I Q +IN NAQ+ Sbjct: 540 ------NQKQNDEDFEKKYLNLKTQFEKLETENQMKQQWQNIQEEEQQEQINTLNAQIVE 593 Query: 1040 MS-MVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQD--DQIKE-- 1094 ++ ++ ++ + T L+ ++ +++SKQ S+QH ++Q + + +++ Sbjct: 594 LNDQLNSTQNLYLKLQTDLQQEVDKNEQLSKQ---SQQHLLDIQNSFNSGNIRNALRKSI 650 Query: 1095 LKETKLTFEMNIPKT--EGMI--ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEF 1150 KE E NI K E I + I+ ++++ + L Q+ + Sbjct: 651 KKEESFEDEANIKKNADEKCINDLKEKIQTLNEELGEYEENQSNLQQQIGELTEQKNKIQ 710 Query: 1151 IQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTEN 1210 +Q + S K ++Q T++ L + + V NQ QI QL+ +L Q+N N Sbjct: 711 LQYEEMYNYYS-KAYDQIQNFITQVEDLNKIILDKENQIVENQYQIQQLEDQLLQMNEIN 769 Query: 1211 DNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQ 1270 + + ++ + + + +QR E E Q+L Q+ Q ++ E +++ + E+ Sbjct: 770 KDAYTENQDI-NQMKAFYEQRFLE-QETLIQNLQQQLE--QTSDQEYYQKMNQILHENEE 825 Query: 1271 LLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEK 1312 L ++S QEE NK + + +Q Q + +LQE+ Sbjct: 826 -LKQLRSENQEELNKKDQLIEELQMQMLSQSQVTGSSDLQER 866 Score = 87.0 bits (206), Expect = 4e-15 Identities = 169/798 (21%), Positives = 327/798 (40%), Gaps = 112/798 (14%) Query: 829 VLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDL 888 VL + ++ E+ L + E + K+ +I ++ + LQ + Q L EK + Sbjct: 14 VLKQYKKMYEEICLRFKFEKEASSKELEIWKDKYETLQKRWDTLNQ----LKEKQDGKTK 69 Query: 889 AESESTKYQTQLRDLESNLKRITHEHQTLIVQ-KKKEIEDLEIEFNTQIESAIRDKKVLN 947 + +K Q+ K H+ +L+ +K++ + L + N QI + KK + Sbjct: 70 QDINDSKTLNQVP------KTSGHQQTSLLPNTEKQQFQILVQQLNEQIA---KQKKQIQ 120 Query: 948 EKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQY 1007 E ++N ++ + K IEN + E+LN+ K +Q Q + +++ Sbjct: 121 ELSDRNEKH------SIDNKKLEIENKKYS-EQLNQFRKTSHHKFNDQQMLQYEENVQKF 173 Query: 1008 INEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRV 1067 I I+++ +++I L ++ + Q S +D K Q K + + + Q Sbjct: 174 IQTIDEMKQEKNSFEKQIEKLTKENQSLQQS-----NDELKKSIQEHDKGQQHKNQFQL- 227 Query: 1068 SKQLLDSKQHNEELQILVREQDDQIKELKE-TKLTF-EMNIPKTEGMIISSTIEPMSDDA 1125 Q+ + N +L+ LV++ + Q + ++ +K T +M+ + E + + ++ + Sbjct: 228 --QISELGLKNNQLEKLVKDLEKQSQHQQDLSKQTAKQMDDKQQEIQSLQNKVQEYQKEL 285 Query: 1126 NNVDXXXXXXXXXXXXLKVQEEEEFIQE-RSVLQEQS--AKLNTELQECYTKIIQLETLN 1182 +N++ L++Q+ + IQE L E + +E+++ K L Sbjct: 286 SNLNQLQDVYNEQQ--LQLQQLAQVIQELEGKLSESTNPQSYESEIKQISIKYDDLYQQY 343 Query: 1183 TELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSS-------ISSAVDQRGFEI 1235 T+L D++ QE +N KS+LE L END L + EL+ I D+ Sbjct: 344 TDLQTQDIMKQEWLNLQKSQLEDLKQENDQLSQKIEELQKQNDVLIGQIEIQKDETKLSS 403 Query: 1236 AELWKQHLAQREADFQKTE--HELRVQLSA---------FESKYEQLLDSVQSSTQEETN 1284 ++L Q + K E H+L+V+L+ +E K +QL + E Sbjct: 404 SQLQDQINSYEHIVSDKNEEIHKLKVELTKQKCSLKNDDYEEKIQQLKTQYEKLESESKM 463 Query: 1285 KIVTME-QVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXX 1343 KI ME Q T L+ + + E+ ++N E+ +NQI E + +K+ Sbjct: 464 KIEWMEIQNTELEETINEYEKKIQNFVEQ----LNQINKNNPEDQSQKIT---------- 509 Query: 1344 XXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVL 1403 +L+ Q Y+ + I+E Q+K+ + D E K L Sbjct: 510 -------ELKEHLQQYELIVNNKNFEIDELKKQIKEINQKQND---------EDFEKKYL 553 Query: 1404 ELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVE-----------YEKRIEDLT 1452 L Q E ++E K I ++ ++ + Q+VE Y K DL Sbjct: 554 NLKTQFEKLETENQMKQQWQNIQEEEQQEQINTLNAQIVELNDQLNSTQNLYLKLQTDLQ 613 Query: 1453 YE--------KESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQ 1504 E K+S+ +L ++ N+ + ++S + +E N+K Sbjct: 614 QEVDKNEQLSKQSQQHLLDIQNSFNSGNIRNALRKSIKKEESFEDEANIKKNADEKCIND 673 Query: 1505 VAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDT 1564 + E + L EE+ + E Q+ L+ Q E+T +N ++ ++ + S A D Sbjct: 674 LKEKIQTLNEELGEYEENQSNLQQQ-------IGELTEQKNKIQLQYEEMYNYYSKAYDQ 726 Query: 1565 KQGRDEQLDNTMNKELLD 1582 Q Q+++ +NK +LD Sbjct: 727 IQNFITQVED-LNKIILD 743 Score = 60.1 bits (139), Expect = 5e-07 Identities = 86/442 (19%), Positives = 190/442 (42%), Gaps = 34/442 (7%) Query: 1189 DVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSA-VDQRGFEIAELWKQHLAQRE 1247 D + QE+ N + ++E+L EN +L + EL+ SI Q+ +L L + Sbjct: 178 DEMKQEK-NSFEKQIEKLTKENQSLQQSNDELKKSIQEHDKGQQHKNQFQLQISELGLKN 236 Query: 1248 ADFQKTEHELRVQLSAFESKYEQL---LDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEE 1304 +K +L Q + +Q +D Q Q NK+ ++ S N+LQD Sbjct: 237 NQLEKLVKDLEKQSQHQQDLSKQTAKQMDDKQQEIQSLQNKVQEYQKELSNLNQLQDVYN 296 Query: 1305 HLRNLQEKYADVINQIEILRSEIEDEKV--AFXXXXXXXXXXXXXXXXDLRTEN---QSY 1359 + ++ A VI ++E SE + + + DL+T++ Q + Sbjct: 297 EQQLQLQQLAQVIQELEGKLSESTNPQSYESEIKQISIKYDDLYQQYTDLQTQDIMKQEW 356 Query: 1360 KQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRV----NDAEAKVLELTHQLELKD-- 1413 +Q+ + ++ +EN QL + ++ ++ + +L Q+ + Sbjct: 357 LNLQKSQLEDLKQENDQLSQKIEELQKQNDVLIGQIEIQKDETKLSSSQLQDQINSYEHI 416 Query: 1414 -SEIYQKTHEYTITLTQ-----RNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMH 1467 S+ ++ H+ + LT+ +ND++E QQL +++E + K + I ++ Sbjct: 417 VSDKNEEIHKLKVELTKQKCSLKNDDYEEKIQQLKTQYEKLESESKMKIEWMEIQNTELE 476 Query: 1468 ENANHYETMQKESEIERVKLI-----EELNVKITESVSLNKQVAELNKALEEEVAKTNEM 1522 E N YE + ++ +E++ I E+ + KITE L + + + + + + +E+ Sbjct: 477 ETINEYE-KKIQNFVEQLNQINKNNPEDQSQKITE---LKEHLQQYELIVNNKNFEIDEL 532 Query: 1523 QTALE--NQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKEL 1580 + ++ NQ+ + NL+ ++ Q + + ++ + EQ+ NT+N ++ Sbjct: 533 KKQIKEINQKQNDEDFEKKYLNLKTQFEKLETENQMKQQWQNIQEEEQQEQI-NTLNAQI 591 Query: 1581 LDAVPRAELDLAMYMLHQRDVR 1602 ++ + +Y+ Q D++ Sbjct: 592 VELNDQLNSTQNLYLKLQTDLQ 613 >UniRef50_A0CCF8 Cluster: Chromosome undetermined scaffold_167, whole genome shotgun sequence; n=4; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_167, whole genome shotgun sequence - Paramecium tetraurelia Length = 2085 Score = 135 bits (326), Expect = 1e-29 Identities = 290/1540 (18%), Positives = 663/1540 (43%), Gaps = 126/1540 (8%) Query: 140 QLGDVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXX 199 Q ++ + NT + + L L+ ++ ++ ++ +++ N++ +I K + T Sbjct: 142 QKQELEQIINTYGDDEKILKQLKQQISVLNEQLV-VEKAYNQEVRIQLKKLQQETQNLND 200 Query: 200 XXXXXXXXXXXXED----TKQQMT--KMQENFIAMEAEWKDEKQRLLKDIESKDVRISSL 253 ED TK Q+ K Q + + K E ++L+ I+ + ++ Sbjct: 201 QLEMKLAEKQDFEDQVAKTKSQLDYLKSQNIMLGIGTPVKGETEKLIA-IDDLVKQNQAV 259 Query: 254 EEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIE-E 312 ++ L+ E H++L +L + L QS+ P E +++E E Sbjct: 260 DDLMNELQTKLLEKQQAHNQLMDQLSKQNIQENEQNSSTS-LRPQSLSPKKELISQLEVE 318 Query: 313 KGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISR 372 + EI K++E+ E L Q+ + +E+ + E + S ++ + SR Sbjct: 319 QHECEIIQQQLKQKQLEI-EELRDQLEKEEQEVFRLQYKLQEEIEVKVSVEQQIQSVQSR 377 Query: 373 K---SGRNTASKMKSPWSQL---SSETLNQDTDKKIN--KNEIAKLEMVIQSLNKDLVDK 424 + T+ ++P + +E++ QD +I+ K I + E I+ L ++ K Sbjct: 378 QLIIEPTVTSYIQEAPTINVFGPQTESIPQDYQFQIDQLKETIKQQESQIEFLKFEIQQK 437 Query: 425 EYVIS-EKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAK--V 481 + +++ + T ++ I +L+ + ++ + N ED K V Sbjct: 438 DEIMNMSQHTYLQDLNQQNQEVESRIQELKKQLSYKIKRKDQLESIVN-EDQKPRRKSFV 496 Query: 482 QEQLKQELNDEI--KDVNVKDLIEKLKSAEEQITQLNDEI---DAANKNMIKVKSNHKLK 536 Q +L +++ K++N+ L E++ ++Q+ E+ D + +K+N Sbjct: 497 QNTELMDLQEQLHEKNMNIVQLYEEISRFQKQLYDKEQELQQRDVELRYQALMKTNEDQC 556 Query: 537 LKQMQKTIDNFSKVSDSNKEIVRLTE------ELHHL-SQKVAELEEEKGNLQLHL---- 585 K + N S + VRL E EL +L S K E+E + N + Sbjct: 557 EKADELVKKNLSMDELIHSLEVRLVEKESKLKELEYLNSSKNFEIESNQNNNSFYKDRES 616 Query: 586 VDYDSG-RMIESDVYKKMIEMENLA---ETRLKAI-SLLESQKFDLVQELHILQQKYDEV 640 + DSG + D + ++ + + + L+ + S +E QK++L ++ I++Q ++ Sbjct: 617 IIRDSGINSYDQDQDHQFVQQQQILAGFNSGLEHLKSRVECQKYELQEKDKIIEQLKQQL 676 Query: 641 ED-KLADISQ--LQSDQVCSEIKSVH-LEEQIDALSASKKELALVIENL-------KLDK 689 D K ++ +Q L + V + ++ L+EQ D L L VI L K + Sbjct: 677 NDLKRSNFNQQILATQDVSVINRQINVLQEQADNLVKQNLALEDVIHELEYKLQEKKNKQ 736 Query: 690 EQLYGTIKDLENDKEDIMN-KLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQ 748 E++ I+++ ++ + K +++N++L +K+++M + I + + E++ Q Sbjct: 737 EEVQQIIQNMMEEEVQLRQLKSDEMVKKNLELDEKIQQMESRLIQKQQQQYELEQRLS-Q 795 Query: 749 TQFGIDAKI----QERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGS 804 Q + ++ +++D+ I++ S LS+ +I ++ ES+ + LE Q Sbjct: 796 HQRSMPQRLPVFHEDQDI-IQDHNSNLSELTIQIAQITESVRQLSQDDIELEFLLKQK-- 852 Query: 805 YLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQN 864 +EKQ + + + L L ++ ++Q+ +++ +NK++++ L + N Sbjct: 853 --KEKQSQIEQLKLFIQSSTDVLQDLQSEQQIKQEQVEKMKSQNKDIEQMVNDLQNQQVN 910 Query: 865 LQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKE 924 L ++ QQ+ + + + +E K Q ++++ NL+ + + Q ++ +K++E Sbjct: 911 LIEDVNKSQQNVPNWLNQNMESSKRLNELQKGQQKVKEQIKNLESLILDLQIVVKEKQEE 970 Query: 925 IEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIE-NLNMNVEELNK 983 ++ + E N Q+ +L K ++ +++ + + L E +E +N V E + Sbjct: 971 LQRISQE-NYQL-------SILTRKQKQKRDHLLREQMPLGEKVGLLEQQVNDLVAENKR 1022 Query: 984 MNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMV 1043 + LEL + + + T++ +I+ L+ Q D+ I+ L I A++ ++ Sbjct: 1023 LQLELARLFQEAESAKQVKQTKE--QQISALSIESSQLDQNIMLLKDDIEQAKILEQQLL 1080 Query: 1044 SDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFE 1103 Q+ K +E+E++ ++ LD N++++ L + ++ K+L E +L E Sbjct: 1081 DQQN----QYKQKNALIEQEIKIYTEMNLDGANINKKIEDLTHQISEE-KQLFE-QLIEE 1134 Query: 1104 MNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQS-A 1162 + I K + ++I + + L+ Q+++ Q+ V QE + Sbjct: 1135 LQIQKEQVLLIVPQKDEIQKLYLQTKQQYDQSVEDLSELQKQQQKVQDQKNQVTQEVNYL 1194 Query: 1163 KLNTELQECYTKIIQLETLNTELTGHDVVNQEQI--NQLKSKLEQLNTE---NDNLLSTV 1217 KL TE QE ++++L+ L +L D + QE N ++ K +++ E N + T Sbjct: 1195 KLFTENQE--KQLVELQALRIKL--DDNIKQENTLKNAIQDKADRIQQELDRNKQAIQTQ 1250 Query: 1218 AELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELR-----VQLSAFESKYEQLL 1272 ++ + +QR +I ++ + Q+ + T+ +++ Q++ + E+L+ Sbjct: 1251 IQILEKQNREKEQRQEQIQKIQTEIEDQKNNLNKLTDQQMKHLYQLDQIAKLDKDMERLM 1310 Query: 1273 DSV---QSSTQEETNKIVTMEQVTSLQ----NKLQDKEEHLRNLQEKYADVINQIEILRS 1325 V + Q+ + +Q + Q N+L+D+ + +E+ I++ + S Sbjct: 1311 KDVFEKEEQVQQYAGLVYQKQQKVNDQKQKFNQLEDELKFYEREEEEIKKRISEQDEKLS 1370 Query: 1326 EIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQL---KKSSX 1382 ++E E DL + + E+ + N NE +L K+ Sbjct: 1371 KLEREFQIRSEKRSKFEDEIAKAEMDLSNLEEMLRNRDEE-LRNFNESKVELMKFKQQYS 1429 Query: 1383 XXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLV 1442 ++ + E + +L+ +++ + ++ + E T + + ++Q+L Sbjct: 1430 TIQGEIREKQEQIQEFEKQRSKLSEEIKKEQEQLTEINQEIYQTKVKEEEMNFQIQQKLK 1489 Query: 1443 EYE------KRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKIT 1496 + + ++++D E+ + + ++ + + ET++KE +I +++E VK Sbjct: 1490 DLDILNDQFRKLDDDAKMLEAVIQLKEKELKQYQDKKETLKKELDIANFQVVE---VK-- 1544 Query: 1497 ESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEI-TNLQNMVRASSSKIQ 1555 LNK+ + K +E + + + AL Q + T N + +LQ +V++ S I Sbjct: 1545 --KQLNKK--KQQKPIEADNNEVEVYEDALSQQISCLNTKNLNLKDDLQRLVQSQSQPIF 1600 Query: 1556 KHVSFASDTKQGRDE-QLDNTMNKELLDAVPRAELDLAMY 1594 + + TK +E QL + LD + + L+M+ Sbjct: 1601 QTMQQIEGTKTQLEELQLTIREKDKKLDILEQQLQQLSMH 1640 Score = 134 bits (324), Expect = 2e-29 Identities = 292/1524 (19%), Positives = 656/1524 (43%), Gaps = 135/1524 (8%) Query: 144 VTHLSNTIKEKDNALSVL----QVKMKIMETTILDLQEKINEKDQIIEAK-NKATTXXXX 198 + L TIK++++ + L Q K +IM + + +N+++Q +E++ + Sbjct: 413 IDQLKETIKQQESQIEFLKFEIQQKDEIMNMSQHTYLQDLNQQNQEVESRIQELKKQLSY 472 Query: 199 XXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANK 258 ED K + +N M+ L + + K++ I L E Sbjct: 473 KIKRKDQLESIVNEDQKPRRKSFVQNTELMD---------LQEQLHEKNMNIVQLYE--- 520 Query: 259 LLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEI 318 E +RF+ L + QEL+Q L K + E CE+ E+ +K Sbjct: 521 --EISRFQKQLYDKE--QELQQRDVELRYQA-----LMKTN-EDQCEKADELVKKN---- 566 Query: 319 ANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNT 378 +M EL +E+ + + + E N ES ++ K I R SG N+ Sbjct: 567 LSMDELIHSLEV-RLVEKESKLKELEYLNSSKNFEIESNQNNNSFYKDRESIIRDSGINS 625 Query: 379 ASKMKSPWSQLSSETL---NQDTDKKINKNEIAKLEM-----VIQSLNKDLVD------K 424 + + + L N + ++ E K E+ +I+ L + L D Sbjct: 626 YDQDQDHQFVQQQQILAGFNSGLEHLKSRVECQKYELQEKDKIIEQLKQQLNDLKRSNFN 685 Query: 425 EYVISEKDTXXXXXXXXXXGK--DTLIAQ-LQLEHQQHMEGPSLIHVGTNTEDVNEIAK- 480 + +++ +D + D L+ Q L LE H L E+V +I + Sbjct: 686 QQILATQDVSVINRQINVLQEQADNLVKQNLALEDVIHELEYKLQEKKNKQEEVQQIIQN 745 Query: 481 -VQE--QLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKL 537 ++E QL+Q +DE+ N+ +L EK++ E ++ Q + + + + + + +L Sbjct: 746 MMEEEVQLRQLKSDEMVKKNL-ELDEKIQQMESRLIQKQQQQYELEQRLSQHQRSMPQRL 804 Query: 538 K---QMQKTI-DNFSKVSDSNKEIVRLTEELHHLSQKVAELE---EEKGNLQLHLVDYDS 590 + Q I D+ S +S+ +I ++TE + LSQ ELE ++K Q + Sbjct: 805 PVFHEDQDIIQDHNSNLSELTIQIAQITESVRQLSQDDIELEFLLKQKKEKQSQIEQLKL 864 Query: 591 GRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQ-QKYDEVEDKLAD--- 646 +DV + ++++ + + + + ++SQ D+ Q ++ LQ Q+ + +ED Sbjct: 865 FIQSSTDVLQ---DLQSEQQIKQEQVEKMKSQNKDIEQMVNDLQNQQVNLIEDVNKSQQN 921 Query: 647 ----ISQ-LQSDQVCSEIKSVH--LEEQIDALSASKKELALVIENLKLDKEQLYGTIKDL 699 ++Q ++S + +E++ ++EQI L + +L +V++ + + +++ L Sbjct: 922 VPNWLNQNMESSKRLNELQKGQQKVKEQIKNLESLILDLQIVVKEKQEELQRISQENYQL 981 Query: 700 ENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQF--GIDAKI 757 K + ++E M L +K+ + +++++L+A+ N Q ++ F AK Sbjct: 982 SILTRKQKQKRDHLLREQMPLGEKVGLLE-QQVNDLVAE-NKRLQLELARLFQEAESAKQ 1039 Query: 758 --QERDLYIENIESELSKYKSRICRLEESIA---VMEDRRYSLERKADQLGSYLQEKQKA 812 Q ++ I + E S+ I L++ I ++E + + + Q + ++++ K Sbjct: 1040 VKQTKEQQISALSIESSQLDQNIMLLKDDIEQAKILEQQLLDQQNQYKQKNALIEQEIKI 1099 Query: 813 YSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILL-EENQNLQISLSD 871 Y+E + + +N+ + H EKQL E E ++QK+ +L+ + +Q Sbjct: 1100 YTEMNL-DGANINKKIEDLTHQISEEKQLFEQLIEELQIQKEQVLLIVPQKDEIQKLYLQ 1158 Query: 872 MQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITH--EHQTLIVQKKKEIEDLE 929 +Q Y+ VE + + + + Q+ + LK T E Q + +Q + D Sbjct: 1159 TKQQYDQSVEDLSELQKQQQKVQDQKNQVTQEVNYLKLFTENQEKQLVELQALRIKLDDN 1218 Query: 930 IEFNTQIESAIRDKKV-LNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLEL 988 I+ +++AI+DK + ++ ++N + + Q + Q+ E K N E E++ K+ E+ Sbjct: 1219 IKQENTLKNAIQDKADRIQQELDRNKQAI-QTQIQILE-KQNREK-EQRQEQIQKIQTEI 1275 Query: 989 IDK--HVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINN-AQVSYMSM--V 1043 D+ ++ K Q + Q +++I KL+ +++ +++ +++ A + Y V Sbjct: 1276 EDQKNNLNKLTDQQMKHLYQ-LDQIAKLDKDMERLMKDVFEKEEQVQQYAGLVYQKQQKV 1334 Query: 1044 SDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFE 1103 +D + K Q +L+ E E + + K++ + + +L+ + + ++ + ++ E Sbjct: 1335 NDQKQKFNQLEDELKFYEREEEEIKKRISEQDEKLSKLEREFQIRSEKRSKFEDEIAKAE 1394 Query: 1104 MNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAK 1163 M++ E M+ + E + + + V+ +++E++E IQE ++Q +K Sbjct: 1395 MDLSNLEEMLRNRDEELRNFNESKVELMKFKQQYSTIQGEIREKQEQIQE---FEKQRSK 1451 Query: 1164 LNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSS 1223 L+ E+++ + QL +N E+ V +E Q++ KL+ L+ ND + + Sbjct: 1452 LSEEIKK---EQEQLTEINQEIYQTKVKEEEMNFQIQQKLKDLDILNDQFRKLDDDAKM- 1507 Query: 1224 ISSAVDQRGFEIAELW-KQHLAQREADFQKTEH-ELRVQLSAFESKYEQLLDSVQSSTQE 1281 + + + + E+ + K+ ++E D + E++ QL+ + K ++ +++ + + Sbjct: 1508 LEAVIQLKEKELKQYQDKKETLKKELDIANFQVVEVKKQLN--KKKQQKPIEA--DNNEV 1563 Query: 1282 ETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVI----NQIEILRSEIEDEKVAFXXX 1337 E + +Q++ L K + ++ L+ L + + I QIE ++++E+ ++ Sbjct: 1564 EVYEDALSQQISCLNTKNLNLKDDLQRLVQSQSQPIFQTMQQIEGTKTQLEELQLTIREK 1623 Query: 1338 XXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVND 1397 L+ + ++ QS ++E L+ + Sbjct: 1624 DKKLDILEQ----QLQQLSMHQSKVTIQSGFYFDDEPLLLELQDKFTKESEMLDD--LQQ 1677 Query: 1398 AEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKES 1457 + E H+L LK + +K H+ I L QR RQ + + EK +E L ++K+S Sbjct: 1678 KLKRTAERHHELALKLQDWAEKEHKLAIELDQR-------RQCVEKIEKELEVL-FQKQS 1729 Query: 1458 ELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVA 1517 +L ++ + + E +E + + + + K L K + E ++E++ Sbjct: 1730 DLESDQVNLQQRMYQLELDNQELNEQEIISLNRIKEKKDYVQVLFKNLIE----MDEKLL 1785 Query: 1518 KTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMN 1577 + + ++ + + N + M S IQ+ + + + ++G + + + Sbjct: 1786 QLRNRMAVYSREGRQLAEQVENLENEKEMREESLQVIQEELE-SLELEKGEKQSMIQQIK 1844 Query: 1578 KELLDA-VPRAELDLAMYMLHQRD 1600 KE+ D + +L++ + H ++ Sbjct: 1845 KEIQDQNTEKDKLEIQYALTHSKN 1868 Score = 111 bits (267), Expect = 2e-22 Identities = 245/1276 (19%), Positives = 544/1276 (42%), Gaps = 113/1276 (8%) Query: 149 NTIKEK-DNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXX 207 N ++E+ DN + ++ LQEK N+++++ + Sbjct: 702 NVLQEQADNLVKQNLALEDVIHELEYKLQEKKNKQEEVQQIIQNMMEEEVQLRQLKSDEM 761 Query: 208 XXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEI 267 + +++ +M+ I + + + +QRL + S R+ E +++ + Sbjct: 762 VKKNLELDEKIQQMESRLIQKQQQQYELEQRLSQHQRSMPQRLPVFHEDQDIIQDHNSNL 821 Query: 268 SLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKK 327 S ++AQ E L ++ + S E+ ++ + S ++ + ++ Sbjct: 822 SELTIQIAQITESVRQLSQDDIELEFLLKQKKEKQSQIEQLKLFIQSSTDVLQDLQSEQQ 881 Query: 328 I-----ELLEHLNCQIRQTNKELENKLATM--GTESKAVSSPSKKGSPLISRK---SGRN 377 I E ++ N I Q +L+N+ + + P+ + S K + Sbjct: 882 IKQEQVEKMKSQNKDIEQMVNDLQNQQVNLIEDVNKSQQNVPNWLNQNMESSKRLNELQK 941 Query: 378 TASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLN----KDLVDKEYVISEKDT 433 K+K L S L+ K + E+ ++ L+ K +++++ E+ Sbjct: 942 GQQKVKEQIKNLESLILDLQIVVKEKQEELQRISQENYQLSILTRKQKQKRDHLLREQMP 1001 Query: 434 XXXXXXXXXXGKDTLIAQ---LQLEHQQ-HMEGPSLIHVG-TNTEDVNEIAKVQEQLKQE 488 + L+A+ LQLE + E S V T + ++ ++ QL Q Sbjct: 1002 LGEKVGLLEQQVNDLVAENKRLQLELARLFQEAESAKQVKQTKEQQISALSIESSQLDQN 1061 Query: 489 LNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAAN---KNMIKVKSNHKLKLKQMQKTID 545 + + +KD IE+ K E+Q+ ++ N + IK+ + L + K I+ Sbjct: 1062 I------MLLKDDIEQAKILEQQLLDQQNQYKQKNALIEQEIKIYTEMNLDGANINKKIE 1115 Query: 546 NFS-KVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQ-LHLV---DYDSGRMIESDVYK 600 + + ++S+ + +L EEL ++V + +K +Q L+L YD S++ K Sbjct: 1116 DLTHQISEEKQLFEQLIEELQIQKEQVLLIVPQKDEIQKLYLQTKQQYDQSVEDLSELQK 1175 Query: 601 ---KMIEMENLAETRLKAISLL-ESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVC 656 K+ + +N + + L E+Q+ LV EL L+ K D+ +I Q + + Sbjct: 1176 QQQKVQDQKNQVTQEVNYLKLFTENQEKQLV-ELQALRIKLDD------NIKQENTLKNA 1228 Query: 657 SEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQE 716 + K+ +++++D + + ++E +KEQ I+ ++ + ED N L + Sbjct: 1229 IQDKADRIQQELDRNKQAIQTQIQILEKQNREKEQRQEQIQKIQTEIEDQKNNLNKLTDQ 1288 Query: 717 NMDLTDKLEKMSA-EKISELLAKINHEEQSKIQTQFGI----DAKIQERDLYIENIESEL 771 M +L++++ +K E L K E++ ++Q G+ K+ ++ +E EL Sbjct: 1289 QMKHLYQLDQIAKLDKDMERLMKDVFEKEEQVQQYAGLVYQKQQKVNDQKQKFNQLEDEL 1348 Query: 772 SKYKSRICRLEESIAVMEDRRYSLER----KADQLGSYLQEKQKAYSEYTIQEDELVNRL 827 Y+ +++ I+ +++ LER ++++ + E KA + + E+ L NR Sbjct: 1349 KFYEREEEEIKKRISEQDEKLSKLEREFQIRSEKRSKFEDEIAKAEMDLSNLEEMLRNRD 1408 Query: 828 AVLMD-HDRVVE-----KQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVE 881 L + ++ VE +Q I+ E +E Q++ Q ++ L + Q+ + + Sbjct: 1409 EELRNFNESKVELMKFKQQYSTIQGEIREKQEQIQEFEKQRSKLSEEIKKEQEQLTEINQ 1468 Query: 882 KANRTDLAESEST-KYQTQLRDLE---SNLKRITHEHQTL--IVQ-KKKEIEDLEIEFNT 934 + +T + E E + Q +L+DL+ +++ + + L ++Q K+KE++ + + T Sbjct: 1469 EIYQTKVKEEEMNFQIQQKLKDLDILNDQFRKLDDDAKMLEAVIQLKEKELKQYQDKKET 1528 Query: 935 -QIESAIRDKKVLNEKYEKNIEYVTQ-LEAQLQEYKNNIENLNMNVEELNKMNLELIDKH 992 + E I + +V+ K + N + + +EA E + + L+ + LN NL L D Sbjct: 1529 LKKELDIANFQVVEVKKQLNKKKQQKPIEADNNEVEVYEDALSQQISCLNTKNLNLKDDL 1588 Query: 993 VQKQQTQS-PDY-TEQYIN----EINKLNALLKQKDEEIIALNQKI-----NNAQVSYMS 1041 + Q+QS P + T Q I ++ +L +++KD+++ L Q++ + ++V+ S Sbjct: 1589 QRLVQSQSQPIFQTMQQIEGTKTQLEELQLTIREKDKKLDILEQQLQQLSMHQSKVTIQS 1648 Query: 1042 -MVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVR---EQDDQIK-ELK 1096 D E L + K E + + ++L + + + EL + ++ E++ ++ EL Sbjct: 1649 GFYFDDEPLLLELQDKFTKESEMLDDLQQKLKRTAERHHELALKLQDWAEKEHKLAIELD 1708 Query: 1097 ETKLTFEMNIPKTEGMIISSTIEPMSDDAN--------NVDXXXXXXXXXXXXLKVQEEE 1148 + + E I K ++ + SD N +D +++E++ Sbjct: 1709 QRRQCVE-KIEKELEVLFQKQSDLESDQVNLQQRMYQLELDNQELNEQEIISLNRIKEKK 1767 Query: 1149 EFIQE--RSVLQ--EQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLE 1204 +++Q +++++ E+ +L + + QL L + +E + ++ +LE Sbjct: 1768 DYVQVLFKNLIEMDEKLLQLRNRMAVYSREGRQLAEQVENLENEKEMREESLQVIQEELE 1827 Query: 1205 QLNTENDNLLSTVAELRSSI---SSAVDQRGFEIA------ELWKQHLAQREADFQKTEH 1255 L E S + +++ I ++ D+ + A + K + E+ ++K + Sbjct: 1828 SLELEKGEKQSMIQQIKKEIQDQNTEKDKLEIQYALTHSKNQQLKLFIGVEESLYKKMQT 1887 Query: 1256 ELRVQLSAFESKYEQLLDSVQSSTQEETNKI-VTMEQVTSLQNKLQDKEEHLRNLQ-EKY 1313 E +Q +SKYE + + T E ++I V M+ + K+ KE L+ L+ E Y Sbjct: 1888 EFEIQQKRDQSKYENMFVCNSTQTYYEVDQIEVLMDNLVG--QKITKKE--LQKLKTECY 1943 Query: 1314 ADVINQIEILRSEIED 1329 ++ +S ++D Sbjct: 1944 TEIQQLFAQNKSYVQD 1959 Score = 110 bits (265), Expect = 3e-22 Identities = 245/1261 (19%), Positives = 547/1261 (43%), Gaps = 151/1261 (11%) Query: 396 QDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLE 455 Q ++ K KN I + EM+ Q + + +D+ +++ + + L +QLQ + Sbjct: 33 QASEIKSLKNRINQKEMLSQPIFDNPIDQ--LLTYPKSLNALGLQIQEEFEKLKSQLQEK 90 Query: 456 HQQ-HM-----EGPSLIHVGTNTEDVNEIAKVQEQLKQ---ELNDEIKDVN-----VKDL 501 Q+ H+ EG + NT V+EI K E++ EL ++ D ++ + Sbjct: 91 EQELHLLRSGIEGQRRSYK-PNTTQVDEIIKQHEEIDDILIELEKKLYDKKQQKQELEQI 149 Query: 502 IEKLKSAEEQITQLNDEIDAANKNMIKVKSNH---KLKLKQMQKTIDNFSKVSDSNKEIV 558 I E+ + QL +I N+ ++ K+ + +++LK++Q+ N N ++ Sbjct: 150 INTYGDDEKILKQLKQQISVLNEQLVVEKAYNQEVRIQLKKLQQETQNL------NDQLE 203 Query: 559 RLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISL 618 E +VA+ + + L+ + G ++ + +K+I +++L + L Sbjct: 204 MKLAEKQDFEDQVAKTKSQLDYLKSQNIMLGIGTPVKGET-EKLIAIDDLVKQNQAVDDL 262 Query: 619 LESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKEL 678 + + L+++ QQ ++++ D+L+ Q+ Q + S L Q +LS KKEL Sbjct: 263 MNELQTKLLEK----QQAHNQLMDQLSK----QNIQENEQNSSTSLRPQ--SLSP-KKEL 311 Query: 679 ALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAK 738 +E + + E + +K + + E++ ++L+ QE L KL++ K+S + + Sbjct: 312 ISQLEVEQHECEIIQQQLKQKQLEIEELRDQLEKEEQEVFRLQYKLQEEIEVKVS-VEQQ 370 Query: 739 INHEEQSKIQTQFGIDAKIQER---DLYIENIESELSKYKSRICRLEESIAVMEDR---- 791 I + ++ + + + IQE +++ ES Y+ +I +L+E+I E + Sbjct: 371 IQSVQSRQLIIEPTVTSYIQEAPTINVFGPQTESIPQDYQFQIDQLKETIKQQESQIEFL 430 Query: 792 RYSLERKADQLG----SYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEH- 846 ++ +++K + + +YLQ+ + E + EL +L+ + +E + E + Sbjct: 431 KFEIQQKDEIMNMSQHTYLQDLNQQNQEVESRIQELKKQLSYKIKRKDQLESIVNEDQKP 490 Query: 847 ------ENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQL 900 +N EL + L E+N N+ ++ + L +K + E +YQ + Sbjct: 491 RRKSFVQNTELMDLQEQLHEKNMNIVQLYEEISRFQKQLYDKEQELQQRDVE-LRYQALM 549 Query: 901 RDLES-------------NLKRITHEHQTLIVQKKKEIEDL---------EIE------- 931 + E ++ + H + +V+K+ ++++L EIE Sbjct: 550 KTNEDQCEKADELVKKNLSMDELIHSLEVRLVEKESKLKELEYLNSSKNFEIESNQNNNS 609 Query: 932 FNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDK 991 F ES IRD + + +++ ++V Q + L + + +E+L V E K L+ DK Sbjct: 610 FYKDRESIIRDSGINSYDQDQDHQFVQQQQI-LAGFNSGLEHLKSRV-ECQKYELQEKDK 667 Query: 992 HVQKQQTQSPDYTEQYINE----------INKLNALLKQKDEEIIALNQKINNAQVSYMS 1041 +++ + Q D N+ IN+ +L+++ + ++ N + + Sbjct: 668 IIEQLKQQLNDLKRSNFNQQILATQDVSVINRQINVLQEQADNLVKQNLALEDVIHELEY 727 Query: 1042 MVSDYESKLAQFTTKLEN-MEEEMQ--------RVSKQL-LDSKQHNEELQILVREQDDQ 1091 + + ++K + ++N MEEE+Q V K L LD K E +++ ++Q Q Sbjct: 728 KLQEKKNKQEEVQQIIQNMMEEEVQLRQLKSDEMVKKNLELDEKIQQMESRLIQKQQ--Q 785 Query: 1092 IKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFI 1151 EL++ + ++P+ + + + D +N+ ++ +++ Sbjct: 786 QYELEQRLSQHQRSMPQ-RLPVFHEDQDIIQDHNSNLSELTIQIAQITESVRQLSQDDI- 843 Query: 1152 QERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTEND 1211 E L +Q + +++++ I + +L + QEQ+ ++KS+ N + + Sbjct: 844 -ELEFLLKQKKEKQSQIEQLKLFIQSSTDVLQDLQSEQQIKQEQVEKMKSQ----NKDIE 898 Query: 1212 NLLSTVAELRSSISSAVDQRGFEIAELWKQHL--AQREADFQKTEHELRVQLSAFESKYE 1269 +++ + + ++ V++ + Q++ ++R + QK + +++ Q+ ES Sbjct: 899 QMVNDLQNQQVNLIEDVNKSQQNVPNWLNQNMESSKRLNELQKGQQKVKEQIKNLESLIL 958 Query: 1270 QLLDSVQSSTQEETNKIVTME-QVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIE 1328 L V QEE +I Q++ L K + K +HL Q + ++ +L ++ Sbjct: 959 D-LQIVVKEKQEELQRISQENYQLSILTRKQKQKRDHLLREQMPLGE---KVGLLEQQVN 1014 Query: 1329 DEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXX 1388 D + + Q KQ +EQ I ++ E++QL ++ Sbjct: 1015 D----LVAENKRLQLELARLFQEAESAKQ-VKQTKEQQISALSIESSQLDQN----IMLL 1065 Query: 1389 XXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYT---ITLTQRNDEFENVRQQLVE-- 1443 + E ++L+ +Q + K++ I Q+ YT + N + E++ Q+ E Sbjct: 1066 KDDIEQAKILEQQLLDQQNQYKQKNALIEQEIKIYTEMNLDGANINKKIEDLTHQISEEK 1125 Query: 1444 --YEKRIEDLTYEKESELAILRLKMHENANHYETMQK-ESEIERVKLIEELNVKITESVS 1500 +E+ IE+L +KE L I+ K + +T Q+ + +E + +++ K+ + Sbjct: 1126 QLFEQLIEELQIQKEQVLLIVPQKDEIQKLYLQTKQQYDQSVEDLSELQKQQQKVQD--Q 1183 Query: 1501 LNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEI---TNLQNMVRASSSKIQKH 1557 N+ E+N ++ N+ + +E Q + I L+D I L+N ++ + +IQ+ Sbjct: 1184 KNQVTQEVNYL---KLFTENQEKQLVELQALRI-KLDDNIKQENTLKNAIQDKADRIQQE 1239 Query: 1558 V 1558 + Sbjct: 1240 L 1240 Score = 99.1 bits (236), Expect = 9e-19 Identities = 230/1208 (19%), Positives = 517/1208 (42%), Gaps = 139/1208 (11%) Query: 468 VGTNTEDVNEIAKVQEQLKQELNDEIKD----VNVKDL---------IEKL----KSAEE 510 V T +D++ + QE++ E EIK +N K++ I++L KS Sbjct: 12 VSTQIQDLDSLISKQEKVINEQASEIKSLKNRINQKEMLSQPIFDNPIDQLLTYPKSLNA 71 Query: 511 QITQLNDEIDAANKNM-IKVKSNHKLKL---KQMQKTIDNFSKVSDSNKEIVRLTEELHH 566 Q+ +E + + K + H L+ Q + N ++V + K+ + + L Sbjct: 72 LGLQIQEEFEKLKSQLQEKEQELHLLRSGIEGQRRSYKPNTTQVDEIIKQHEEIDDILIE 131 Query: 567 LSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDL 626 L +K+ + +++K L+ + Y I + K+ I + N KA + + + L Sbjct: 132 LEKKLYDKKQQKQELEQIINTYGDDEKILKQL-KQQISVLNEQLVVEKAYN--QEVRIQL 188 Query: 627 VQELHILQQKYDEVEDKLADISQLQSDQVCSE------IKSVHLEEQIDALSASKKELAL 680 + Q D++E KLA+ + DQV +KS ++ I + E + Sbjct: 189 KKLQQETQNLNDQLEMKLAEKQDFE-DQVAKTKSQLDYLKSQNIMLGIGTPVKGETEKLI 247 Query: 681 VIENLKLDKEQLYGTIKDLEN---DKEDIMNKLQNY-----IQEN-MDLTDKLEKMSAEK 731 I++L + + + +L+ +K+ N+L + IQEN + + L S Sbjct: 248 AIDDLVKQNQAVDDLMNELQTKLLEKQQAHNQLMDQLSKQNIQENEQNSSTSLRPQSLSP 307 Query: 732 ISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDR 791 EL++++ EQ + + I +++++ L IE + +L K + + RL+ + + Sbjct: 308 KKELISQL-EVEQHECEI---IQQQLKQKQLEIEELRDQLEKEEQEVFRLQYKLQEEIEV 363 Query: 792 RYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRL-----AVLMDHD-------RVVEK 839 + S+E++ + S + + Y IQE +N ++ D+ +++ Sbjct: 364 KVSVEQQIQSVQSRQLIIEPTVTSY-IQEAPTINVFGPQTESIPQDYQFQIDQLKETIKQ 422 Query: 840 QLLEIEHENKELQKKNQI-----------LLEENQNLQISLSDMQQHYNALVEKANRTDL 888 Q +IE E+Q+K++I L ++NQ ++ + ++++ + +++ ++ + Sbjct: 423 QESQIEFLKFEIQQKDEIMNMSQHTYLQDLNQQNQEVESRIQELKKQLSYKIKRKDQLES 482 Query: 889 AESESTK-------YQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIR 941 +E K T+L DL+ L HE IVQ +EI F Q+ + Sbjct: 483 IVNEDQKPRRKSFVQNTELMDLQEQL----HEKNMNIVQLYEEIS----RFQKQLYD--K 532 Query: 942 DKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEEL-NKMNLELIDKHVQKQQTQS 1000 ++++ E + + + E + + N++++EL + + + L++K + ++ + Sbjct: 533 EQELQQRDVELRYQALMKTNEDQCEKADELVKKNLSMDELIHSLEVRLVEKESKLKELEY 592 Query: 1001 PDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENM 1060 + ++ + E N+ N KD E I + IN+ + LA F + LE++ Sbjct: 593 LNSSKNFEIESNQNNNSF-YKDRESIIRDSGINSYDQDQDHQFVQQQQILAGFNSGLEHL 651 Query: 1061 EEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGM-IISSTIE 1119 + RV Q K +E ++ + Q+ +LK + F I T+ + +I+ I Sbjct: 652 K---SRVECQ----KYELQEKDKIIEQLKQQLNDLKRS--NFNQQILATQDVSVINRQIN 702 Query: 1120 PMSDDANNVDXXXXXXXXXXXXL--KVQE---EEEFIQE--RSVLQEQSAKLNTELQECY 1172 + + A+N+ L K+QE ++E +Q+ +++++E+ + E Sbjct: 703 VLQEQADNLVKQNLALEDVIHELEYKLQEKKNKQEEVQQIIQNMMEEEVQLRQLKSDEMV 762 Query: 1173 TKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSI---SSAVD 1229 K ++L+ ++ + Q+Q +L+ +L Q L E + I +S + Sbjct: 763 KKNLELDEKIQQMESRLIQKQQQQYELEQRLSQHQRSMPQRLPVFHEDQDIIQDHNSNLS 822 Query: 1230 QRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQE----ETNK 1285 + +IA++ + + Q D + E L+ Q +S+ EQL +QSST ++ + Sbjct: 823 ELTIQIAQI-TESVRQLSQDDIELEFLLK-QKKEKQSQIEQLKLFIQSSTDVLQDLQSEQ 880 Query: 1286 IVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQI--------EILRSEIEDEK-VAFXX 1336 + EQV ++++ +D E+ + +LQ + ++I + L +E K + Sbjct: 881 QIKQEQVEKMKSQNKDIEQMVNDLQNQQVNLIEDVNKSQQNVPNWLNQNMESSKRLNELQ 940 Query: 1337 XXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQL-------KKSSXXXXXXXX 1389 L + Q + +++ + I++EN QL K+ Sbjct: 941 KGQQKVKEQIKNLESLILDLQIVVKEKQEELQRISQENYQLSILTRKQKQKRDHLLREQM 1000 Query: 1390 XXXXRVNDAEAKVLEL---THQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEK 1446 +V E +V +L +L+L+ + ++Q+ + + + + + ++ Sbjct: 1001 PLGEKVGLLEQQVNDLVAENKRLQLELARLFQEAESAKQVKQTKEQQISALSIESSQLDQ 1060 Query: 1447 RIEDLTYEKESELAILRLKMHENANHYETMQKESEIER-VKLIEELNVKITESVSLNKQV 1505 I L + E + IL ++ + N Y+ QK + IE+ +K+ E+N+ + ++NK++ Sbjct: 1061 NIMLLKDDIE-QAKILEQQLLDQQNQYK--QKNALIEQEIKIYTEMNL---DGANINKKI 1114 Query: 1506 AELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTK 1565 +L + EE ++ L+ Q+ +++ + + +Q + + + + V S+ + Sbjct: 1115 EDLTHQISEEKQLFEQLIEELQIQKEQVLLIVPQKDEIQKLYLQTKQQYDQSVEDLSELQ 1174 Query: 1566 QGRDEQLD 1573 + + + D Sbjct: 1175 KQQQKVQD 1182 Score = 97.5 bits (232), Expect = 3e-18 Identities = 195/992 (19%), Positives = 431/992 (43%), Gaps = 109/992 (10%) Query: 166 KIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENF 225 KI+E +LD Q + +K+ +IE + K T ED Q+++ ++ F Sbjct: 1073 KILEQQLLDQQNQYKQKNALIEQEIKIYTEMNLDGANINKKI----EDLTHQISEEKQLF 1128 Query: 226 IAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXX 285 + E + +K+++L + KD I L K +++ S+E Q+ +Q Sbjct: 1129 EQLIEELQIQKEQVLLIVPQKD-EIQKLYLQTK----QQYDQSVEDLSELQKQQQKVQDQ 1183 Query: 286 XXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKEL 345 K E ++ ++ E +L I + ++ L + + + +EL Sbjct: 1184 KNQVTQEVNYLKLFTE---NQEKQLVELQALRIKLDDNIKQENTLKNAIQDKADRIQQEL 1240 Query: 346 ENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKN 405 + + T+ + + +++ ++ + ++++ + L+ T +Q + Sbjct: 1241 DRNKQAIQTQIQILEKQNREKEQ--RQEQIQKIQTEIEDQKNNLNKLT-DQQMKHLYQLD 1297 Query: 406 EIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQ--LEHQQHMEGP 463 +IAKL+ ++ L KD+ +KE + + + QL+ L+ + E Sbjct: 1298 QIAKLDKDMERLMKDVFEKEEQVQQYAGLVYQKQQKVNDQKQKFNQLEDELKFYEREEEE 1357 Query: 464 SLIHVGTNTEDVNEIAK---VQEQLKQELNDEIK--DVNVKDLIEKLKSAEEQITQLNDE 518 + E ++++ + ++ + + + DEI ++++ +L E L++ +E++ N+ Sbjct: 1358 IKKRISEQDEKLSKLEREFQIRSEKRSKFEDEIAKAEMDLSNLEEMLRNRDEELRNFNE- 1416 Query: 519 IDAANKNMIKVKSNHKL---KLKQMQKTIDNFSKV-SDSNKEIVRLTEELHHLSQKV--A 572 + ++K K + ++++ Q+ I F K S ++EI + E+L ++Q++ Sbjct: 1417 ---SKVELMKFKQQYSTIQGEIREKQEQIQEFEKQRSKLSEEIKKEQEQLTEINQEIYQT 1473 Query: 573 ELEEEKGNLQLH--LVDYD-----------SGRMIESDVY---KKMIEMENLAETRLKAI 616 +++EE+ N Q+ L D D +M+E+ + K++ + ++ ET K + Sbjct: 1474 KVKEEEMNFQIQQKLKDLDILNDQFRKLDDDAKMLEAVIQLKEKELKQYQDKKETLKKEL 1533 Query: 617 SLLESQKFDLVQELHIL-QQKYDEVEDKLADISQ-LQSDQV-CSEIKSVHLEEQIDALSA 673 + Q ++ ++L+ QQK E ++ ++ + S Q+ C K+++L++ + L Sbjct: 1534 DIANFQVVEVKKQLNKKKQQKPIEADNNEVEVYEDALSQQISCLNTKNLNLKDDLQRLVQ 1593 Query: 674 SKKELALV----IENLKLDKEQLYGTIKDLENDKEDIMNKLQNY--------IQENMDLT 721 S+ + IE K E+L TI++ + + + +LQ IQ Sbjct: 1594 SQSQPIFQTMQQIEGTKTQLEELQLTIREKDKKLDILEQQLQQLSMHQSKVTIQSGFYFD 1653 Query: 722 DK---LEKMSA-EKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSR 777 D+ LE K SE+L + + + + + K+Q+ + EL + + Sbjct: 1654 DEPLLLELQDKFTKESEMLDDLQQKLKRTAERHHELALKLQDWAEKEHKLAIELDQRRQC 1713 Query: 778 ICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVV 837 + ++E+ + V+ ++ LE L + + + E QE +NR+ D+ +V+ Sbjct: 1714 VEKIEKELEVLFQKQSDLESDQVNLQQRMYQLELDNQELNEQEIISLNRIKEKKDYVQVL 1773 Query: 838 EKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQ 897 K L+E++ + +L+ + + E + L + +++ N ++ E Q Sbjct: 1774 FKNLIEMDEKLLQLRNRMAVYSREGRQLAEQVENLE----------NEKEMREESLQVIQ 1823 Query: 898 TQLRDLESNLKRITHEHQTLIVQKKKEIED-------LEIEF------NTQIESAIRDKK 944 +L LE L++ E Q++I Q KKEI+D LEI++ N Q++ I ++ Sbjct: 1824 EELESLE--LEK--GEKQSMIQQIKKEIQDQNTEKDKLEIQYALTHSKNQQLKLFIGVEE 1879 Query: 945 VLNEKYEKNIEYVTQLEAQLQEYKN----NIENLNMNVEELNKMNLELIDKHVQKQQTQS 1000 L +K + E+ Q + +Y+N N V+++ + L+ + + K++ Q Sbjct: 1880 SLYKKMQ--TEFEIQQKRDQSKYENMFVCNSTQTYYEVDQIEVLMDNLVGQKITKKELQK 1937 Query: 1001 PDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTK---- 1056 TE Y EI +L A K ++ + + I Q+ + V + E+ L TK Sbjct: 1938 LK-TECY-TEIQQLFAQNKSYVQDNVNVRNLIQFQQI--LIQVVESENILLSEKTKCRKS 1993 Query: 1057 LENMEEEMQRVSKQLLDSKQHNEEL-QILVRE 1087 L EE + +L+D+ ++ L +I + E Sbjct: 1994 LTIQSEEQNTFTLELIDTIMNSSSLIEISINE 2025 Score = 94.7 bits (225), Expect = 2e-17 Identities = 208/1081 (19%), Positives = 463/1081 (42%), Gaps = 112/1081 (10%) Query: 222 QENF--IAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELE 279 QEN+ + + K ++ LL++ ++ LE+ L A + LE ++L QE E Sbjct: 976 QENYQLSILTRKQKQKRDHLLREQMPLGEKVGLLEQQVNDLVAENKRLQLELARLFQEAE 1035 Query: 280 QXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIR 339 L SIE S ++ + K +E A + E +LL+ N Q + Sbjct: 1036 SAKQVKQTKEQQISAL---SIESSQLDQNIMLLKDDIEQAKILEQ----QLLDQQN-QYK 1087 Query: 340 QTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTD 399 Q N +E ++ TE G N K++ Q+S E Q + Sbjct: 1088 QKNALIEQEIKIY-TEMNL---------------DGANINKKIEDLTHQISEE--KQLFE 1129 Query: 400 KKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQH 459 + I + +I K ++++ KD + K Y+ +++ K Q +++ Q++ Sbjct: 1130 QLIEELQIQKEQVLLIVPQKDEIQKLYLQTKQQYDQSVEDLSELQKQ----QQKVQDQKN 1185 Query: 460 MEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEI 519 + ++ TE+ + + L+ +L+D IK N L ++ ++I Q D Sbjct: 1186 QVTQEVNYLKLFTENQEKQLVELQALRIKLDDNIKQENT--LKNAIQDKADRIQQELDRN 1243 Query: 520 DAANKNMIKVKSNHKLKLKQMQKTIDNF-SKVSDSNKEIVRLTEE-LHHLSQ--KVAELE 575 A + I++ + +Q Q+ I +++ D + +LT++ + HL Q ++A+L+ Sbjct: 1244 KQAIQTQIQILEKQNREKEQRQEQIQKIQTEIEDQKNNLNKLTDQQMKHLYQLDQIAKLD 1303 Query: 576 EEKGNLQLHLVDYDSG-RMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQ 634 ++ L + + + + VY+K + + + + K L + KF +E I + Sbjct: 1304 KDMERLMKDVFEKEEQVQQYAGLVYQKQ---QKVNDQKQKFNQLEDELKFYEREEEEI-K 1359 Query: 635 QKYDEVEDKLADIS---QLQSDQVCS---EIKSVHLE-EQIDALSASKKELALVIENLKL 687 ++ E ++KL+ + Q++S++ EI ++ ++ + ++ E K+ Sbjct: 1360 KRISEQDEKLSKLEREFQIRSEKRSKFEDEIAKAEMDLSNLEEMLRNRDEELRNFNESKV 1419 Query: 688 DK---EQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQ 744 + +Q Y TI+ +K++ ++Q + ++ L+++++K E+++E+ +I + Sbjct: 1420 ELMKFKQQYSTIQGEIREKQE---QIQEFEKQRSKLSEEIKK-EQEQLTEINQEIYQTKV 1475 Query: 745 SKIQTQFGIDAKIQERDLY---IENIESELSKYKSRICRLEESIAVMEDRRYSLERKAD- 800 + + F I K+++ D+ ++ + ++ I E+ + +D++ +L+++ D Sbjct: 1476 KEEEMNFQIQQKLKDLDILNDQFRKLDDDAKMLEAVIQLKEKELKQYQDKKETLKKELDI 1535 Query: 801 ----------QLGSYLQEK--QKAYSEYTIQEDELVNRLAVLM--------DHDRVVEKQ 840 QL Q+K + +E + ED L +++ L D R+V+ Q Sbjct: 1536 ANFQVVEVKKQLNKKKQQKPIEADNNEVEVYEDALSQQISCLNTKNLNLKDDLQRLVQSQ 1595 Query: 841 -------LLEIEHENKELQKKNQILLEENQNLQISLSDMQQ---HYNALVEKA-----NR 885 + +IE +L++ + E+++ L I +QQ H + + ++ + Sbjct: 1596 SQPIFQTMQQIEGTKTQLEELQLTIREKDKKLDILEQQLQQLSMHQSKVTIQSGFYFDDE 1655 Query: 886 TDLAESES--TKYQTQLRDLESNLKRITHEHQTLIVQKKKEIED---LEIEFNTQIESAI 940 L E + TK L DL+ LKR H L ++ + E L IE + + + Sbjct: 1656 PLLLELQDKFTKESEMLDDLQQKLKRTAERHHELALKLQDWAEKEHKLAIELDQRRQCVE 1715 Query: 941 RDKKVLNEKYEKNIEYVT-QLEAQLQEYKNNIENLNMNVEELNKMN-LELIDKHVQKQQT 998 + +K L ++K + + Q+ Q + Y+ ++N +N +E+ +N ++ +VQ Sbjct: 1716 KIEKELEVLFQKQSDLESDQVNLQQRMYQLELDNQELNEQEIISLNRIKEKKDYVQVLFK 1775 Query: 999 QSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLE 1058 + E+ + N++ A+ ++ ++ + + N + + + +L + Sbjct: 1776 NLIEMDEKLLQLRNRM-AVYSREGRQLAEQVENLENEKEMREESLQVIQEELESLELEKG 1834 Query: 1059 NMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTI 1118 + +Q++ K++ D ++L+I + ++LK + E ++ K M I Sbjct: 1835 EKQSMIQQIKKEIQDQNTEKDKLEIQYALTHSKNQQLK-LFIGVEESLYKK--MQTEFEI 1891 Query: 1119 EPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQ-ECYTKIIQ 1177 + D + + + ++ E + + V Q+ + K +L+ ECYT+I Q Sbjct: 1892 QQKRDQSKYENMFVCNSTQTYYEV---DQIEVLMDNLVGQKITKKELQKLKTECYTEIQQ 1948 Query: 1178 LETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAE 1237 L N D VN + Q + L Q+ + LLS + R S++ +++ E Sbjct: 1949 LFAQNKSYV-QDNVNVRNLIQFQQILIQVVESENILLSEKTKCRKSLTIQSEEQNTFTLE 2007 Query: 1238 L 1238 L Sbjct: 2008 L 2008 Score = 82.2 bits (194), Expect = 1e-13 Identities = 188/955 (19%), Positives = 417/955 (43%), Gaps = 101/955 (10%) Query: 706 IMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIE 765 ++ + IQ+ L K EK+ E+ SE+ + N Q ++ +Q D I + Y + Sbjct: 8 LLKVVSTQIQDLDSLISKQEKVINEQASEIKSLKNRINQKEMLSQPIFDNPIDQLLTYPK 67 Query: 766 NIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVN 825 ++ + L +++E ++ + E++ L S ++ ++++Y T Q DE++ Sbjct: 68 SLNA-LG------LQIQEEFEKLKSQLQEKEQELHLLRSGIEGQRRSYKPNTTQVDEIIK 120 Query: 826 RLAVLMDHDRVVEKQLLEIEHENKEL---------------QKKNQI-LLEE-------- 861 + + D +EK+L + + + +EL Q K QI +L E Sbjct: 121 QHEEIDDILIELEKKLYDKKQQKQELEQIINTYGDDEKILKQLKQQISVLNEQLVVEKAY 180 Query: 862 NQNLQISLSDMQQHYNAL-----VEKANRTDLAESESTKYQTQLRDLES-NL-----KRI 910 NQ ++I L +QQ L ++ A + D E + K ++QL L+S N+ + Sbjct: 181 NQEVRIQLKKLQQETQNLNDQLEMKLAEKQDF-EDQVAKTKSQLDYLKSQNIMLGIGTPV 239 Query: 911 THEHQTLI-----VQKKKEIEDLEIEFNTQ-IESAIRDKKVLNEKYEKNIE-----YVTQ 959 E + LI V++ + ++DL E T+ +E +++++ ++NI+ T Sbjct: 240 KGETEKLIAIDDLVKQNQAVDDLMNELQTKLLEKQQAHNQLMDQLSKQNIQENEQNSSTS 299 Query: 960 LEAQ-LQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALL 1018 L Q L K I L + E + +L K ++ ++ + D E+ E+ +L L Sbjct: 300 LRPQSLSPKKELISQLEVEQHECEIIQQQLKQKQLEIEELR--DQLEKEEQEVFRLQYKL 357 Query: 1019 KQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHN 1078 +++ E +++ Q+I + Q S ++ + Q + + + + + D + Sbjct: 358 QEEIEVKVSVEQQIQSVQ-SRQLIIEPTVTSYIQEAPTINVFGPQTESIPQ---DYQFQI 413 Query: 1079 EELQILVREQDDQIKELKETKLTFEMNIPKTEGMIIS--STIEPMSDDANNVDXXXXXXX 1136 ++L+ +++Q+ QI+ LK FE+ K E M +S + ++ ++ V+ Sbjct: 414 DQLKETIKQQESQIEFLK-----FEIQ-QKDEIMNMSQHTYLQDLNQQNQEVE-SRIQEL 466 Query: 1137 XXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQI 1196 K++ +++ E V ++Q + + +Q T+++ L+ E + V E+I Sbjct: 467 KKQLSYKIKRKDQL--ESIVNEDQKPRRKSFVQN--TELMDLQEQLHEKNMNIVQLYEEI 522 Query: 1197 NQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHE 1256 ++ + +QL + L ELR ++ E A+ L ++ + H Sbjct: 523 SRFQ---KQLYDKEQELQQRDVELRYQALMKTNEDQCEKAD----ELVKKNLSMDELIHS 575 Query: 1257 LRVQLSAFESKYEQL--LDSVQS----STQEETNKIVTMEQV---TSLQNKLQDKEEHLR 1307 L V+L ESK ++L L+S ++ S Q + E + + + + QD++ Sbjct: 576 LEVRLVEKESKLKELEYLNSSKNFEIESNQNNNSFYKDRESIIRDSGINSYDQDQDHQFV 635 Query: 1308 NLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSI 1367 Q+ A + +E L+S +E +K DL+ N + + + Q + Sbjct: 636 QQQQILAGFNSGLEHLKSRVECQKYEL-QEKDKIIEQLKQQLNDLKRSNFNQQILATQDV 694 Query: 1368 LNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITL 1427 IN + L++ + +++ E K+ E ++ E + +I Q E + L Sbjct: 695 SVINRQINVLQEQADNLVKQNLALEDVIHELEYKLQEKKNKQE-EVQQIIQNMMEEEVQL 753 Query: 1428 TQ-RNDEFENVRQQLVEYEKRIEDLTYEKESELAIL--RLKMHENA--NHYETMQKESEI 1482 Q ++DE +L E +++E +K+ + L RL H+ + ++ +I Sbjct: 754 RQLKSDEMVKKNLELDEKIQQMESRLIQKQQQQYELEQRLSQHQRSMPQRLPVFHEDQDI 813 Query: 1483 --ERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEI 1540 + + EL ++I + +Q+++ + LE + + E Q+ +E ++ I + D + Sbjct: 814 IQDHNSNLSELTIQIAQITESVRQLSQDDIELEFLLKQKKEKQSQIEQLKLFIQSSTDVL 873 Query: 1541 TNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDLAMYM 1595 +LQ+ + +++K S D +Q ++ + +N L++ V +++ ++ ++ Sbjct: 874 QDLQSEQQIKQEQVEKMKSQNKDIEQMVNDLQNQQVN--LIEDVNKSQQNVPNWL 926 >UniRef50_UPI00006CD8D3 Cluster: hypothetical protein TTHERM_00522610; n=1; Tetrahymena thermophila SB210|Rep: hypothetical protein TTHERM_00522610 - Tetrahymena thermophila SB210 Length = 1547 Score = 134 bits (325), Expect = 1e-29 Identities = 231/1235 (18%), Positives = 537/1235 (43%), Gaps = 94/1235 (7%) Query: 370 ISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIA----KLEMVIQSLNKDLVDK- 424 IS KS +M++ +Q + NQD + ++ + I++L ++ +++ Sbjct: 12 ISYKSSDQDKQQMQNIQAQQDLQQNNQDQSQSNGQSNSQFTPQDVAFYIENLKRNYLERL 71 Query: 425 ---EYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHM----EGPSLIHVGTNTEDVNE 477 E + S K+ K+ L Q E + ++ E S++ + + + Sbjct: 72 EGDEVIDSLKNDPELESFRVERFKEILKQSFQYEQELYIDKMIEANSMLKLDLKKSEEEK 131 Query: 478 IAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKL 537 ++ EQ K E+ + K V + + ++A++ + Q E KN+ K + LK+ Sbjct: 132 YIEI-EQAKIEIQNISKKVLEFESAIQQEAAQKMVLQNEYEKLLKQKNLEKANYDELLKI 190 Query: 538 KQMQKT-IDNFSK--VSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMI 594 K+ +T D+ K + +S EI L +E +L + +++++ L +L Y Sbjct: 191 KESSQTKQDSMYKQELQNSRMEIESLLKEKSNLQIQNEQMKDQIDTLTKNLQIYSQKHQA 250 Query: 595 ESD---VY-KKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQL 650 S+ +Y +K EM+N+ + I LES + +++LH+ Q+ ++ LA+ +Q Sbjct: 251 RSETDRIYEQKNEEMKNIIQKLQTQIVDLESSNENCIEQLHLKDQEIQVIKTSLAE-TQK 309 Query: 651 QSDQVCSEIKSVHLE-EQIDALSASKK-ELALVIENLKLDKEQLYGTIKDLENDKEDIMN 708 ++D + + + + ++ ++++L K EL+ +E ++ K+ L K+ N + I Sbjct: 310 ENDYLSNNTEKLKVQIAKLESLVNEKSGELSKKLEKVRSKKKAL----KEKFNQNKQI-- 363 Query: 709 KLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIE 768 L+N+ +E +++ AE+ + + + I+ ++ E++ I + Sbjct: 364 -LENHSREISQYKKNIQE-QAEQYERTIQGMK-GDMLTIKNEWEKRCNEVEKECQI-LVN 419 Query: 769 SELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLA 828 +KY+ + ++++ + D++ ++ D+ + L + S+ + ++ Sbjct: 420 QSKTKYEMQAQKIKQEYQQLLDKKM---QELDESTNQLNFSKGFNSQIQTKIQQIEKDYI 476 Query: 829 VLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDL 888 + H++++E ++ ++E +++EL NQI N+Q + ++ E+ +R Sbjct: 477 LKEQHEKILEGEIAKLEAKHQEL--INQISEIHQNNIQAKIKEIS-------ERKSRE-- 525 Query: 889 AESESTKYQTQLRDLESNLK---RITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKV 945 E+ S Q DL++ L+ ++T +++ I++ + ++ E N Q I K + Sbjct: 526 YETLSQGLQNNCLDLQAKLQDQIKLTAQYKEKILEVENNFYKIKDEINQQ-NQYINVKLL 584 Query: 946 LNEKYEKNIEYV--TQLEAQLQEYKN---NIENLNMNVEELNKMNLELIDKHVQKQQTQS 1000 K + N+ Y QL+ Q +E+ N N+EN +N ++ + ++ K V++ + Sbjct: 585 GFFKLQINLSYFMKKQLKGQNEEHINHRKNLENKILNYQQ-DLEDIRNSKKQVEEALQEQ 643 Query: 1001 PDYTEQYINEINKLNALLK---QKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKL 1057 + ++ I KL L+ QK+E+ N+++ N ++ YES+ +L Sbjct: 644 LELSQMQSESIQKLQTNLEEYNQKEEQWQNENEELQN------NLQQQYESQ-ESLKRQL 696 Query: 1058 ENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISST 1117 E ++++ + + + + Q E +++ ++ ++ +E K+ L E + + + Sbjct: 697 EQIKQKQEVEKQSAIRNVQFQESIKL--EKEKEEHEETKQKLLQLERKVKQVQ-KEQEKI 753 Query: 1118 IEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSA---KLNTELQE-CYT 1173 E + + L+ ++++ IQ + Q+ A K+N + Q C Sbjct: 754 NEDYEERLQQMQEKSIKISGQKEKLETEKKDLIIQVNEIQQKYEAFTSKINRDKQRICKR 813 Query: 1174 KIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGF 1233 +QL++L +L+ D+ N Q++ +K+ +++ + ++ ++ + +++ Sbjct: 814 LGLQLKSLKDDLS--DIQNDSQLD--IAKIYEVSKQ--TIVQSIDHFNNLKQREINKLEN 867 Query: 1234 EIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVT 1293 + + ++ L + ++ E LR Q ++ + ++D ++S ++ +KI ++ Sbjct: 868 QFRQNQEEILNEFNEKMEQIEENLRNQANSTNVDLQNIIDQLKSENEQLQDKISSLLASQ 927 Query: 1294 SLQNKLQDK-EEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDL 1352 L K + K E L NL EK+ + + I SE +E F L Sbjct: 928 ELIEKEKKKLESQLSNL-EKHNEKLEGIIKRNSEDMEEHNKFFAAEIKRIKDESNSLVQL 986 Query: 1353 RTENQSYKQMQEQSILNINEENAQ-LKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLE- 1410 ++ QE IL Q + + + + E + EL Q E Sbjct: 987 AVDSALQSSKQEIDILQKKIATLQSMNEKAKAKEDTIYDLNREIQQREGNIDELQKQFEQ 1046 Query: 1411 ---LKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMH 1467 +KD EI QK L E +++ +++ E + ++ E +L + + Sbjct: 1047 NMKIKDEEI-QKKENLIEKLRAELQEMQHIYEKMQEENNQAFEVL---EKKLENYKQAIS 1102 Query: 1468 ENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALE 1527 A Y+ ++++S +E L EEL + + + ++ +Q + N A +E+ +T ++ L Sbjct: 1103 SEAQKYQMVKEQSNLEIQSLNEELEI-VRQQLATKEQNID-NLAKYQEL-QTYSKRSQLP 1159 Query: 1528 NQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFAS 1562 Q I+ N++ T Q H++ S Sbjct: 1160 QQFIQNQLQNNQTTQAQQTHNLPPQPPSSHLNTTS 1194 Score = 87.0 bits (206), Expect = 4e-15 Identities = 153/754 (20%), Positives = 314/754 (41%), Gaps = 69/754 (9%) Query: 388 QLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDT 447 QL + +K +N+I + ++ + E + E+ T Sbjct: 600 QLKGQNEEHINHRKNLENKILNYQQDLEDIRNSKKQVEEALQEQLELSQMQSESIQKLQT 659 Query: 448 LIAQL-QLEHQQHMEGPSLIHVGTNTEDVNEIAKVQ-EQLKQ----ELNDEIKDVNVKDL 501 + + Q E Q E L + + E K Q EQ+KQ E I++V ++ Sbjct: 660 NLEEYNQKEEQWQNENEELQNNLQQQYESQESLKRQLEQIKQKQEVEKQSAIRNVQFQES 719 Query: 502 IEKLKSAEE------QITQLNDEIDAANKNMIKVKSNHKLKLKQMQ-KTIDNFSKVSDSN 554 I+ K EE ++ QL ++ K K+ +++ +L+QMQ K+I + Sbjct: 720 IKLEKEKEEHEETKQKLLQLERKVKQVQKEQEKINEDYEERLQQMQEKSIKISGQKEKLE 779 Query: 555 KEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLK 614 E L +++ + QK E K N + G ++S + + +++N +++L Sbjct: 780 TEKKDLIIQVNEIQQKY-EAFTSKINRDKQRICKRLGLQLKS-LKDDLSDIQN--DSQLD 835 Query: 615 AISLLESQKFDLVQEL-HILQQKYDEVEDKLADISQLQSDQVCSEI--KSVHLEEQI-DA 670 + E K +VQ + H K E+ +KL + + +++ +E K +EE + + Sbjct: 836 IAKIYEVSKQTIVQSIDHFNNLKQREI-NKLENQFRQNQEEILNEFNEKMEQIEENLRNQ 894 Query: 671 LSASKKELALVIENLKLDKEQLYGTIKDL-------ENDKEDIMNKLQNYIQENMDLTDK 723 +++ +L +I+ LK + EQL I L E +K+ + ++L N + N L + Sbjct: 895 ANSTNVDLQNIIDQLKSENEQLQDKISSLLASQELIEKEKKKLESQLSNLEKHNEKL-EG 953 Query: 724 LEKMSAEKISE----LLAKINH-EEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRI 778 + K ++E + E A+I +++S Q +D+ +Q I+ ++ +++ +S Sbjct: 954 IIKRNSEDMEEHNKFFAAEIKRIKDESNSLVQLAVDSALQSSKQEIDILQKKIATLQS-- 1011 Query: 779 CRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVE 838 + E ED Y L R+ Q + E QK + + +DE + + L++ R Sbjct: 1012 --MNEKAKAKEDTIYDLNREIQQREGNIDELQKQFEQNMKIKDEEIQKKENLIEKLRA-- 1067 Query: 839 KQLLEIEHENKELQKKN----QILLEENQNLQISLSDMQQHYNALVEKANRTDLAESEST 894 +L E++H +++Q++N ++L ++ +N + ++S Q Y + E++N + +E Sbjct: 1068 -ELQEMQHIYEKMQEENNQAFEVLEKKLENYKQAISSEAQKYQMVKEQSNLEIQSLNEEL 1126 Query: 895 KY-QTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKN 953 + + QL E N+ + + K+ ++ I+ Q + ++ N + Sbjct: 1127 EIVRQQLATKEQNIDNLAKYQELQTYSKRSQLPQQFIQNQLQNNQTTQAQQTHNLPPQPP 1186 Query: 954 IEYVTQLEAQLQEYKNNIE----NLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQY-- 1007 ++ + ++NN + + + K N + +Q S + + Sbjct: 1187 SSHLNTTSSVFSTHRNNQQYPQQQTSYSAVRTLKQNNSASNLIATQQNNNSSSFNISHQP 1246 Query: 1008 -------INEINKLNALLKQ-KDEEIIALNQKINN--------AQVSYMSMVSDYESKLA 1051 I +N LN K K E LNQ + A SY+ S +S A Sbjct: 1247 GNNSASKIQNVNYLNYNEKPVKLEATNQLNQASTHQTQFYKYQADKSYVKQYSLDKSFDA 1306 Query: 1052 QFTTKLENMEEEMQRVSKQLLDSKQHNEELQILV 1085 Q L ++ + + VS+ L S+Q N + + V Sbjct: 1307 QRLDTLSDLSRQHKIVSQAKLASQQQNSQASLSV 1340 >UniRef50_A0EEQ9 Cluster: Chromosome undetermined scaffold_92, whole genome shotgun sequence; n=3; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_92, whole genome shotgun sequence - Paramecium tetraurelia Length = 1107 Score = 134 bits (325), Expect = 1e-29 Identities = 217/1047 (20%), Positives = 450/1047 (42%), Gaps = 84/1047 (8%) Query: 502 IEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVS-DSNKEIVRL 560 IE LK AE Q L + N+N H+L++KQ+ + I N+ + + D ++ + Sbjct: 78 IEFLKQAEAQSKMLTTQFQEMNQN-------HQLEVKQLLEQIQNYKQRNVDLKSQVEQY 130 Query: 561 TEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLK-AISLL 619 EL+ + K E E+ + +Y + D+ K ++ ++ LK I + Sbjct: 131 MTELNKSNLKYQECCRERDEYLKNFREYSQ----DYDIMKMQLQGKDAEIVSLKDRIHNI 186 Query: 620 E-SQKFDLVQELHILQQ-KYDEVEDKLADIS-QLQSDQVCSEIKSVHLEEQIDALSASKK 676 E S + +L Q + K ++ ++ +I+ Q D++ S+IK +LE + L Sbjct: 187 ESSHQQELTQYSQTNEHWKRSLMDTQIKEITQQFNQDRIQSDIKIKNLENKNIELENKCV 246 Query: 677 ELALVIENLKL-DKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMS--AEKIS 733 LA +E +++ D EQ K+L+N+ ++ K+Q +Q +++ +M ++ Sbjct: 247 LLAQEMERMRVKDLEQNKVVNKNLQNENNELKAKIQEMMQFITRYEEQINEMEFYQDQDQ 306 Query: 734 ELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRY 793 + KI + I+ + Q+ Y + I+ L +Y+ + LEE + + Sbjct: 307 KDRMKIVVLSSEIERLHCVIEEQQQQTQSYQQQIQG-LEQYEMQCQLLEEQQLLNNQLKE 365 Query: 794 SLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQK 853 L+++ ++ + LQ+++ E+T++ EL ++ A+L E + L + N + Sbjct: 366 QLDQEVEKNQNTLQQQEYYQQEWTVRNQELQDKCAML-----TTELERLNLVTRNNDRSS 420 Query: 854 KNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHE 913 +N E ++LQ ++ H+ + EK+N E E + YQ + L S+ + Sbjct: 421 RN--YQYEIESLQ---KQLENHFQIVEEKSNIILQLEMEISNYQQESMLLNSDNDNLNMR 475 Query: 914 HQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNI-- 971 I Q ++EI++++ + + Q ++ + E Y + T Q + K ++ Sbjct: 476 ----ITQLEEEIQEIKDQASQQQSRRSQELRQQIEYYANELNRTTYNYNQANQDKESLHQ 531 Query: 972 --ENLNMNVEEL----NKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQK--DE 1023 E +N ++L + ++E+ D + Q Q + E INE+ K L++ D+ Sbjct: 532 EYEKINREYKDLFFTSQQKDIEIKDLYDQIQLIRDKHQIE--INELKKQGEYLRRSVLDQ 589 Query: 1024 EIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQI 1083 +I L +K NN + ++ D + + Q + + M+ M +Q L Q+ + Q+ Sbjct: 590 QIRDLTEKFNNDKQAF-----DMQFRQLQQSKQQVEMQNSM---LQQNLQELQYTVDGQL 641 Query: 1084 LVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLK 1143 ++ Q Q E + L E+ + E +S+ M +D L Sbjct: 642 EIQRQKLQTSEKERINLLQEIKDYQMELQRVSNERFQMKEDFVKERMKIVIYATEIDRL- 700 Query: 1144 VQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKL 1203 E+F + +EQ+ N ++Q+ TL T+ H+ ++ ++ + K+ L Sbjct: 701 WSVIEDFTNQIKKTEEQNRLQNDQIQQL--------TLTTQ-QYHNTISTLELEK-KNHL 750 Query: 1204 EQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSA 1263 + N + +L + + + + + +Q E + +++Q + Q+ Q+ E EL Q+ + Sbjct: 751 RENNMKEQSLENKMIVMTNELERTKNQLYEEQSRVYEQEIKQKSL-LQEIE-ELYQQIES 808 Query: 1264 FESKYEQL----LDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQ 1319 ++S+ + L+ T+ + ++ Q L N++QD E+ + L ++ + Sbjct: 809 YQSEITIMQKNGLEVGDLETKFQAERMSWETQKYQLNNQIQDYEQRVHLLSQEIKRLTTI 868 Query: 1320 IEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKK 1379 + EIE+ + F DL E Q + EQS L + L+K Sbjct: 869 GDERLHEIEELRFKFRDASLAENYEQLKTEYDL-LEQQVME--LEQSNLKLKSHTQTLEK 925 Query: 1380 SSXXXXXXXXXXXXRVNDAEAKVLELTHQLEL--KDSEIYQKTHEYTITLTQRNDEFENV 1437 V D + + Q E K++E +KT + L Q Sbjct: 926 QIQLLELSLQDKSREVEDIYNLMNKQRRQSESTNKEAENNRKTQQ---QLQQTISNLGQQ 982 Query: 1438 RQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEI-ERVKLIEELNVKIT 1496 QQL E + + + +S++ ++ +HE + +K SE+ E++K I+ L VK Sbjct: 983 NQQLKEQLQTVNNENQSLQSQIQYMQNSLHERDQMIQ--KKSSELTEKIKEIDSLKVKYE 1040 Query: 1497 ESV--SLNKQVAELNKALEEEVAKTNE 1521 + + S+ + N ++ +V KT++ Sbjct: 1041 QKMNNSIIQSTVIRNSSITRQVIKTDQ 1067 Score = 96.3 bits (229), Expect = 6e-18 Identities = 189/932 (20%), Positives = 386/932 (41%), Gaps = 104/932 (11%) Query: 704 EDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKIN----HEEQSKIQTQFGIDAKIQE 759 + ++ ++QNY Q N+DL ++E+ E L +E K ++ D I + Sbjct: 107 KQLLEQIQNYKQRNVDLKSQVEQYMTELNKSNLKYQECCRERDEYLKNFREYSQDYDIMK 166 Query: 760 RDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLER---KADQLGSYLQEKQKAYSEY 816 L + ++E+ K RI +E S E +YS K + + ++E + +++ Sbjct: 167 MQL--QGKDAEIVSLKDRIHNIESSHQ-QELTQYSQTNEHWKRSLMDTQIKEITQQFNQD 223 Query: 817 TIQEDELVNRLA---VLMDHDRVVEKQLLEIEHENKELQKK--NQILLEENQNLQISLSD 871 IQ D + L + +++ V+ Q +E Q K N+ L EN L+ + + Sbjct: 224 RIQSDIKIKNLENKNIELENKCVLLAQEMERMRVKDLEQNKVVNKNLQNENNELKAKIQE 283 Query: 872 MQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKR---ITHEHQTLIVQKKKEIEDL 928 M Q E+ N + + + K + ++ L S ++R + E Q +++I+ L Sbjct: 284 MMQFITRYEEQINEMEFYQDQDQKDRMKIVVLSSEIERLHCVIEEQQQQTQSYQQQIQGL 343 Query: 929 E-IEFNTQI--ESAIRD---KKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLN----MNV 978 E E Q+ E + + K+ L+++ EKN + Q E QE+ + L M Sbjct: 344 EQYEMQCQLLEEQQLLNNQLKEQLDQEVEKNQNTLQQQEYYQQEWTVRNQELQDKCAMLT 403 Query: 979 EELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVS 1038 EL ++NL + ++ + E ++ ++++K I+ L +I+N Q Sbjct: 404 TELERLNL--VTRNNDRSSRNYQYEIESLQKQLENHFQIVEEKSNIILQLEMEISNYQQE 461 Query: 1039 YMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKET 1098 M + SD ++ ++ +EEE+Q + Q S+Q + Q L ++ + EL T Sbjct: 462 SMLLNSDNDN----LNMRITQLEEEIQEIKDQA--SQQQSRRSQELRQQIEYYANELNRT 515 Query: 1099 KLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQ 1158 T+ N + + E ++ + D + ++ + I+++ ++ Sbjct: 516 --TYNYNQANQDKESLHQEYEKINREYK--DLFFTSQQKDIEIKDLYDQIQLIRDKHQIE 571 Query: 1159 EQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVA 1218 K E Q+ L + Q QL+ +Q+ +N L + Sbjct: 572 INELKKQGEYLRRSVLDQQIRDLTEKFNNDKQAFDMQFRQLQQSKQQVEMQNSMLQQNLQ 631 Query: 1219 ELRSSISSAVD--QRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESK--------- 1267 EL+ ++ ++ ++ + +E + +L Q D+Q RV F+ K Sbjct: 632 ELQYTVDGQLEIQRQKLQTSEKERINLLQEIKDYQMELQ--RVSNERFQMKEDFVKERMK 689 Query: 1268 ---YEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEI-- 1322 Y +D + S ++ TN+I E+ LQN D+ + L ++Y + I+ +E+ Sbjct: 690 IVIYATEIDRLWSVIEDFTNQIKKTEEQNRLQN---DQIQQLTLTTQQYHNTISTLELEK 746 Query: 1323 ---LRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQ-MQEQSILNINEENAQLK 1378 LR E+ +++ Y+Q ++++S+L EE Q Sbjct: 747 KNHLRENNMKEQSLENKMIVMTNELERTKNQLYEEQSRVYEQEIKQKSLLQEIEELYQQI 806 Query: 1379 KSSXXXXXXXXXXXXRVNDAEAKV-----------LELTHQLELKDSEIY---QKTHEYT 1424 +S V D E K +L +Q++ + ++ Q+ T Sbjct: 807 ESYQSEITIMQKNGLEVGDLETKFQAERMSWETQKYQLNNQIQDYEQRVHLLSQEIKRLT 866 Query: 1425 ITLTQRNDEFENVR-----QQLVE-YE--KRIEDLTYEKESELAILRLKMHENANHYETM 1476 +R E E +R L E YE K DL ++ EL LK+ +H +T+ Sbjct: 867 TIGDERLHEIEELRFKFRDASLAENYEQLKTEYDLLEQQVMELEQSNLKLK---SHTQTL 923 Query: 1477 QKESEIERVKL------IEEL----NVKITESVSLNKQVAELNKALEEEVAKTNEMQTAL 1526 +K+ ++ + L +E++ N + +S S NK+ AE N+ ++++ +T Sbjct: 924 EKQIQLLELSLQDKSREVEDIYNLMNKQRRQSESTNKE-AENNRKTQQQLQQTIS-NLGQ 981 Query: 1527 ENQEI--EIVTLNDEITNLQNMVRASSSKIQK 1556 +NQ++ ++ T+N+E +LQ+ ++ + + + Sbjct: 982 QNQQLKEQLQTVNNENQSLQSQIQYMQNSLHE 1013 Score = 76.6 bits (180), Expect = 5e-12 Identities = 166/827 (20%), Positives = 336/827 (40%), Gaps = 108/827 (13%) Query: 743 EQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQL 802 E+ + +F A+ Q + L + E ++ + +L E I + R L+ + +Q Sbjct: 72 EEKNREIEFLKQAEAQSKMLTTQFQEMN-QNHQLEVKQLLEQIQNYKQRNVDLKSQVEQY 130 Query: 803 GSYLQEKQKAYSEYTIQEDE-LVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEE 861 + L + Y E + DE L N D+D +++ QL + E L+ + + Sbjct: 131 MTELNKSNLKYQECCRERDEYLKNFREYSQDYD-IMKMQLQGKDAEIVSLKDRIHNIESS 189 Query: 862 NQNLQISLSDMQQHYN-ALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQ-TLIV 919 +Q S +H+ +L++ + + + Q+ ++ K I E++ L+ Sbjct: 190 HQQELTQYSQTNEHWKRSLMDTQIKEITQQFNQDRIQSDIKIKNLENKNIELENKCVLLA 249 Query: 920 QKKKEIEDLEIEFNTQIESAIRDKK-VLNEKYEKNIEYVTQLEAQLQE---YKNNIENLN 975 Q+ + + ++E N + ++++ L K ++ ++++T+ E Q+ E Y++ + Sbjct: 250 QEMERMRVKDLEQNKVVNKNLQNENNELKAKIQEMMQFITRYEEQINEMEFYQDQDQKDR 309 Query: 976 MNVEELNKMNLELIDKHVQKQQTQSPDYT------EQY------INEINKLNALLKQKDE 1023 M + L+ +E + +++QQ Q+ Y EQY + E LN LK++ + Sbjct: 310 MKIVVLSS-EIERLHCVIEEQQQQTQSYQQQIQGLEQYEMQCQLLEEQQLLNNQLKEQLD 368 Query: 1024 EIIALNQKINNAQVSYMSMVS----DYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNE 1079 + + NQ Q Y + + + K A TT+LE + + + + + E Sbjct: 369 QEVEKNQNTLQQQEYYQQEWTVRNQELQDKCAMLTTELERLNLVTRNNDRSSRNYQYEIE 428 Query: 1080 ELQILVREQDDQIKELKETKLTFEMNIP--KTEGMIISSTIEPMSDDANNVDXXXXXXXX 1137 LQ + ++E L EM I + E M+++S D +N++ Sbjct: 429 SLQKQLENHFQIVEEKSNIILQLEMEISNYQQESMLLNS-------DNDNLN-------- 473 Query: 1138 XXXXLKVQEEEEFIQE-RSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQI 1196 +++ + EE IQE + +Q ++ + EL++ LN ++ NQ++ Sbjct: 474 ----MRITQLEEEIQEIKDQASQQQSRRSQELRQQIE--YYANELNRTTYNYNQANQDK- 526 Query: 1197 NQLKSKLEQLNTENDNLLST-------VAELRSSISSAVDQRGFEIAELWKQHLAQREAD 1249 L + E++N E +L T + +L I D+ EI EL KQ R + Sbjct: 527 ESLHQEYEKINREYKDLFFTSQQKDIEIKDLYDQIQLIRDKHQIEINELKKQGEYLRRSV 586 Query: 1250 FQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNL 1309 + +L + + + ++ +Q S Q+ +QN + + NL Sbjct: 587 LDQQIRDLTEKFNNDKQAFDMQFRQLQQSKQQ-----------VEMQNSMLQQ-----NL 630 Query: 1310 QEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILN 1369 QE V Q+EI R +++ + +L E + Y QM+ Q + N Sbjct: 631 QELQYTVDGQLEIQRQKLQTSE---------------KERINLLQEIKDY-QMELQRVSN 674 Query: 1370 INEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQ 1429 E Q+K+ ++ + + + T+Q++ KT E Sbjct: 675 ---ERFQMKEDFVKERMKIVIYATEIDRLWSVIEDFTNQIK--------KTEEQN---RL 720 Query: 1430 RNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIE 1489 +ND+ + + +Y I L EK++ L +K N M E E + +L E Sbjct: 721 QNDQIQQLTLTTQQYHNTISTLELEKKNHLRENNMKEQSLENKMIVMTNELERTKNQLYE 780 Query: 1490 ELNVKITESV---SLNKQVAELNKALEEEVAKTNEMQ-TALENQEIE 1532 E + + + SL +++ EL + +E ++ MQ LE ++E Sbjct: 781 EQSRVYEQEIKQKSLLQEIEELYQQIESYQSEITIMQKNGLEVGDLE 827 Score = 74.1 bits (174), Expect = 3e-11 Identities = 157/856 (18%), Positives = 349/856 (40%), Gaps = 67/856 (7%) Query: 144 VTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXX 203 + +L N E +N +L +M+ M L+ + +N+ Q + KA Sbjct: 231 IKNLENKNIELENKCVLLAQEMERMRVKDLEQNKVVNKNLQNENNELKAKIQEMMQFITR 290 Query: 204 XXXXXXXXEDTKQQMTKMQENFIAMEAEWK------DEKQRLLKDIESKDVRISSLEEAN 257 E + Q K + + + +E + +E+Q+ + + + + E Sbjct: 291 YEEQINEMEFYQDQDQKDRMKIVVLSSEIERLHCVIEEQQQQTQSYQQQIQGLEQYEMQC 350 Query: 258 KLLEAARFEISLEHSKLAQELE--QXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGS 315 +LLE + + +L QE+E Q + Q ++ C T E+ + Sbjct: 351 QLLEEQQLLNNQLKEQLDQEVEKNQNTLQQQEYYQQEWTVRNQELQDKCAMLTTELERLN 410 Query: 316 LEIANMTELTKKIEL-LEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKS 374 L N ++ + +E L Q+ + +E K + +S+ ++ L S Sbjct: 411 LVTRNNDRSSRNYQYEIESLQKQLENHFQIVEEKSNIILQLEMEISNYQQESMLLNSDND 470 Query: 375 GRNTA-SKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDT 433 N ++++ ++ + Q + + + ++E LN+ + +K++ Sbjct: 471 NLNMRITQLEEEIQEIKDQASQQQSRRSQELRQ--QIEYYANELNRTTYNYNQANQDKES 528 Query: 434 XXXXXXXXXXG-KDTLIAQLQ--LEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELN 490 KD Q +E + + LI E +NE+ K E L++ + Sbjct: 529 LHQEYEKINREYKDLFFTSQQKDIEIKDLYDQIQLIRDKHQIE-INELKKQGEYLRRSVL 587 Query: 491 DEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKV 550 D+ ++DL EK + ++ ++ + + + S + L+++Q T+D Sbjct: 588 DQ----QIRDLTEKFNNDKQAFDMQFRQLQQSKQQVEMQNSMLQQNLQELQYTVDG---- 639 Query: 551 SDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEM-ENLA 609 EI R QK+ E+E+ NL + DY +M V + +M E+ Sbjct: 640 ---QLEIQR---------QKLQTSEKERINLLQEIKDY---QMELQRVSNERFQMKEDFV 684 Query: 610 ETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCS-EIKSVHLEEQI 668 + R+K + + + + D + +++ ++++ K + ++LQ+DQ+ + + I Sbjct: 685 KERMKIV--IYATEIDRLWS--VIEDFTNQIK-KTEEQNRLQNDQIQQLTLTTQQYHNTI 739 Query: 669 DALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMS 728 L KK L N+K ++ L + + N+ E N+L Y +++ ++++ S Sbjct: 740 STLELEKKN-HLRENNMK--EQSLENKMIVMTNELERTKNQL--YEEQSRVYEQEIKQKS 794 Query: 729 A-EKISELLAKI-NHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIA 786 ++I EL +I +++ + I + G++ E E + E KY+ L I Sbjct: 795 LLQEIEELYQQIESYQSEITIMQKNGLEVGDLETKFQAERMSWETQKYQ-----LNNQIQ 849 Query: 787 VMEDRRYSLERKADQLGSYLQEKQKAYSE--YTIQEDELVNRLAVLMDHDRVVEKQLLEI 844 E R + L ++ +L + E+ E + ++ L L ++E+Q++E+ Sbjct: 850 DYEQRVHLLSQEIKRLTTIGDERLHEIEELRFKFRDASLAENYEQLKTEYDLLEQQVMEL 909 Query: 845 EHENKELQKKNQILLEENQNLQISLSDMQQH----YNALVEKANRTDLAESEST---KYQ 897 E N +L+ Q L ++ Q L++SL D + YN + ++ +++ E+ K Q Sbjct: 910 EQSNLKLKSHTQTLEKQIQLLELSLQDKSREVEDIYNLMNKQRRQSESTNKEAENNRKTQ 969 Query: 898 TQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYV 957 QL+ SNL + + + + E + L+ + S +++ +K + E + Sbjct: 970 QQLQQTISNLGQQNQQLKEQLQTVNNENQSLQSQIQYMQNSLHERDQMIQKKSSELTEKI 1029 Query: 958 TQLEAQLQEYKNNIEN 973 ++++ +Y+ + N Sbjct: 1030 KEIDSLKVKYEQKMNN 1045 >UniRef50_Q3V6T2 Cluster: Girdin; n=53; Euteleostomi|Rep: Girdin - Homo sapiens (Human) Length = 1871 Score = 134 bits (325), Expect = 1e-29 Identities = 227/1096 (20%), Positives = 448/1096 (40%), Gaps = 75/1096 (6%) Query: 475 VNEIAKVQEQLKQELND-EIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNH 533 V+++ + K+ L+D E V++L E + E T L D+++ K+ Sbjct: 322 VDKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELE 381 Query: 534 KLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRM 593 K L+ K D + K+I L EE L + +E +L L Sbjct: 382 KENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTSE 441 Query: 594 IESDVYKKM-IEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQS 652 + K + E+ L +RL LE + L + + L+ D VE + I +++ Sbjct: 442 LSEAPQKSLGHEVNELTSSRLLK---LEMENQSLTKTVEELRTTVDSVEGNASKILKMEK 498 Query: 653 DQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQN 712 + K LE +I S + + ++L +K QL TI+ L + E + L+ Sbjct: 499 ENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILE- 557 Query: 713 YIQENMDLTDKLEKMSAEKISELLAKINH-EEQSKI--QTQFGIDAKIQERDLYIENIES 769 QEN L + + A++ E+++KI ++ +K+ + + I+ Sbjct: 558 --QENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKK 615 Query: 770 ELSKYKS---RICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNR 826 EL YK R LE + +E L++K L EK +A + + + + Sbjct: 616 ELEHYKEKGERAEELENELHHLEKENELLQKKITNL-KITCEKIEALEQENSELERENRK 674 Query: 827 LAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRT 886 L +D + + QL +E EN +L ++N L ++L+ + M Q ++ N+ Sbjct: 675 LKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQ-----LQLENKE 729 Query: 887 DLAESESTKYQTQLRDLE-SNLKRITHEHQTLIVQKKKEIEDLEIEFNT--QIESAIRDK 943 +E E K +L +R+ +Q L ++ ++ + LE Q+ES ++D Sbjct: 730 LESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDL 789 Query: 944 KVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQ-KQQTQSPD 1002 ++ N+ +KN+E + +L++ + ++L +L K +L ++ + +QQ + D Sbjct: 790 EMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKD 849 Query: 1003 YTEQY----INEINKLNALLKQK----DEEIIALNQK-------INNAQVSYMSMVSDYE 1047 T + I + K N L ++ E + L + + A + ++V+ E Sbjct: 850 TTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLRE 909 Query: 1048 SKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKL--TFEMN 1105 +++ K + M ++++++ +L + E L + DD +L E+KL T + + Sbjct: 910 DLVSE-KLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLESKLESTLKKS 968 Query: 1106 IPKTEGMI--ISSTIEPMSDDANNVDXXXXXXXXXXXXLKV-QEEEEFIQERSVLQEQSA 1162 + E I + + +E ++ + LK Q+EE +Q + + Sbjct: 969 LEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGEDN 1028 Query: 1163 KLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRS 1222 K E QE ++++++ E+ ++ Q + LK++L+QL T+N+NL + + L+ Sbjct: 1029 KWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQR 1088 Query: 1223 SISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEE 1282 S +Q L + A Q L Q ++ ++ QLL S E Sbjct: 1089 QTVSLQEQ---------NTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENEN 1139 Query: 1283 TNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXX 1342 + I E + SL + L E L L E+ A ++ E L S+ K A Sbjct: 1140 ESVIKEREDLKSLYDSLIKDHEKLELLHERQA---SEYESLISKHGTLKSAHKNLEVEHR 1196 Query: 1343 XXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKV 1402 L+ + Q + +++ +L + +E L+ + ND Sbjct: 1197 DLEDRYNQLLKQKGQ-LEDLEK--MLKVEQEKMLLENKNHETVAAEYKKLCGENDR---- 1249 Query: 1403 LELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAIL 1462 L T+ LK++E+ Q H+ +L N + E R + E+ K E+ +L I Sbjct: 1250 LNHTYSQLLKETEVLQTDHKNLKSLL-NNSKLEQTRLE-AEFSK-----LKEQYQQLDIT 1302 Query: 1463 RLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEE----VAK 1518 K++ ++ E E L++++ + ++ +L +Q E E + K Sbjct: 1303 STKLNNQCELLSQLKGNLEEENRHLLDQIQTLMLQNRTLLEQNMESKDLFHVEQRQYIDK 1362 Query: 1519 TNEMQTALENQEIEIV 1534 NE++ E E +I+ Sbjct: 1363 LNELRRQKEKLEEKIM 1378 Score = 112 bits (269), Expect = 9e-23 Identities = 226/1099 (20%), Positives = 472/1099 (42%), Gaps = 95/1099 (8%) Query: 479 AKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLK 538 AK++ +L+QEL + K + D ++L+ E ++ +L E N N++ + ++ Sbjct: 258 AKIR-RLRQELEE--KTEQLLDCKQELEQMEIELKRLQQE----NMNLLSDARSARMYRD 310 Query: 539 QMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQL------HLVDYDSGR 592 ++ + +V E+ R E LH + A +EE K + Q+ L D G Sbjct: 311 ELDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGT 370 Query: 593 MIESDVYKKMIEMENL-AETRLKAISL---LESQKF-DLVQELHILQ----QKYDEVEDK 643 SD + +E ENL + +L + + ++ +K +L++E L+ Q DE Sbjct: 371 RARSDKLHE-LEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHL 429 Query: 644 LADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDK--EQLYGTIKDLEN 701 ++ Q+ SE L +++ L++S+ L L +EN L K E+L T+ +E Sbjct: 430 GWELEQISRTSELSEAPQKSLGHEVNELTSSRL-LKLEMENQSLTKTVEELRTTVDSVEG 488 Query: 702 DKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQS------KIQTQFGIDA 755 + I+ K++ +EN L+ K+E + E + E + N + S K Q + I+ Sbjct: 489 NASKIL-KME---KENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIET 544 Query: 756 KIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRY-SLERKADQLGSYLQEKQKAYS 814 + + I+ +E E + L + + + R +E++ L ++E S Sbjct: 545 LRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLS 604 Query: 815 EYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQ- 873 + ++ ++ L +H + ++ E+E+E L+K+N++L ++ NL+I+ ++ Sbjct: 605 KIEFEKRQIKKEL----EHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEA 660 Query: 874 -QHYNALVEKANRTDLAESESTKYQT-QLRDLESNLKRITHEHQTL--IVQKKK----EI 925 + N+ +E+ NR +S K T QL LE ++ E+ L V+ K ++ Sbjct: 661 LEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKM 720 Query: 926 EDLEIEFNTQIESAIRDKK----VLNEKYEK--NIEYVTQ-LEAQLQEYKNNIENLNMNV 978 L++E N ++ES K +L ++K +E Q L+ + Q + +EN N + Sbjct: 721 AQLQLE-NKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKI 779 Query: 979 EELNK--MNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQ 1036 ++L +LE+ ++ +QK + + + + ++ K N L+Q+ ++ +++ Sbjct: 780 QQLESELQDLEMENQTLQK-NLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKEN 838 Query: 1037 VSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELK 1096 ++ L + K+ N+E+E + +SK++ K+ L+ L +E + + K Sbjct: 839 KRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELV---K 895 Query: 1097 ETKLTFEMNIPKTEGMIISS-TIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERS 1155 + + + E ++ + M++D + L E+ Sbjct: 896 RATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYK 955 Query: 1156 VLQ---EQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDN 1212 +L+ E + K + E++E KI LE E T ++ ++++ +K E L D Sbjct: 956 LLESKLESTLKKSLEIKE--EKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDE 1013 Query: 1213 LLSTVAELRSSISSAVDQRGFEIAELWKQHL--AQREADFQKTEHELRVQLSAFESKYEQ 1270 + + IS ++ E E ++ L R + ++ L+ + A +++ +Q Sbjct: 1014 --ERMVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQ 1071 Query: 1271 L---LDSVQSSTQEETNKIVTM-EQVTSLQN---KLQDKEEHLRNLQEKYADVINQIEIL 1323 L +++Q+ + V++ EQ T+LQ KLQ + L + + Q+ I Sbjct: 1072 LETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQ 1131 Query: 1324 RSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXX 1383 +S +E+E + D + + + Q ++ ++ LK + Sbjct: 1132 QSSLENENESVIKEREDLKSLYDSLIKD-HEKLELLHERQASEYESLISKHGTLKSAHKN 1190 Query: 1384 XXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVE 1443 R N ++L+ QLE D E K + + L +N E + + Sbjct: 1191 LEVEHRDLEDRYN----QLLKQKGQLE--DLEKMLKVEQEKMLLENKNHETVAAEYKKLC 1244 Query: 1444 YEKRIEDLTYE---KESELAIL---RLKMHENANHYETMQKESEIERVK-LIEELNVKIT 1496 E + TY KE+E+ LK N + E + E+E ++K ++L++ T Sbjct: 1245 GENDRLNHTYSQLLKETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITST 1304 Query: 1497 ESVSLNKQVAELNKALEEE 1515 + + + +++L LEEE Sbjct: 1305 KLNNQCELLSQLKGNLEEE 1323 Score = 106 bits (255), Expect = 4e-21 Identities = 181/868 (20%), Positives = 388/868 (44%), Gaps = 72/868 (8%) Query: 295 LAKQSIEPSCEE-KTEIE--EKGSLEIANMTE----LTKKIELLEHLNCQIRQT------ 341 + QS+ + EE +T ++ E + +I M + L+KK+E+LE+ Q +Q+ Sbjct: 467 MENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQN 526 Query: 342 -NKELENKLATMGTESKAVSSPSKKGSPLISRKSG--RNTASKMKSPWSQLSSETLNQDT 398 +K+L + A + + + S++ ++ +++ T S ++ SQ+S+E +D Sbjct: 527 LSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQR-SQISAEARVKDI 585 Query: 399 DKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQ 458 +K+ NK ++ L+K +K + E + ++ L LE + Sbjct: 586 EKE-NKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENEL---HHLEKEN 641 Query: 459 HMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDV--NVKDLIEKLKSAEEQITQLN 516 + + ++ E + + + +L++E N ++K + K+L +L+S E++ +QL+ Sbjct: 642 ELLQKKITNLKITCEKIEALEQENSELERE-NRKLKKTLDSFKNLTFQLESLEKENSQLD 700 Query: 517 DEIDAANKNMIKVKSNHKLKLKQMQ---KTIDNFSKVSDSNKEIVRLT-EELHHLSQKVA 572 +E +N+ +K +K+ Q+Q K +++ + E+++ + ++ L Sbjct: 701 EENLELRRNVESLKC-ASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQ 759 Query: 573 ELEEEKGNLQLHLVDYDSG-RMIESDVYKKMIEMEN-LAETRLKAISLLESQKFDLVQEL 630 L+ E LQ L + + + +ES++ + +EMEN + L+ + + + L +E Sbjct: 760 GLDIENQRLQKTLENSNKKIQQLESEL--QDLEMENQTLQKNLEELKISSKRLEQLEKEN 817 Query: 631 HILQQKYDEVE-DKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDK 689 L+Q+ ++E DK + + + +EIK LEE + +KE + + + + K Sbjct: 818 KSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYK 877 Query: 690 EQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKL--EKMSAEKISELLAKINHE-EQSK 746 E +K+LE + ++++ + I+ + L + L EK+ ++++ L K+ HE E+ Sbjct: 878 ESCV-RLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIG 936 Query: 747 IQTQFGIDAKIQERDLYIENIESEL-SKYKSRICRLEESIAVMEDRRYSLERKADQLGSY 805 + + + + D + +ES+L S K + EE IA +E R QL Sbjct: 937 LNKERLLHDEQSTDDSRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQE 996 Query: 806 LQEKQKAYSEYTIQEDE--LVNRLAVLMDHDRVVE-------KQLLEIEHENKELQKKNQ 856 L+ +K Y ++DE +V + D E ++LL+++ E+++ N Sbjct: 997 LKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVERNNA 1056 Query: 857 ILLEENQNLQISLSDMQQHYNAL----VEKANRTDLAESESTKYQTQLRDLESNLKRITH 912 L E Q L+ L ++ N L + +T + ++T QTQ L+ + + Sbjct: 1057 TLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTL-N 1115 Query: 913 EHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQL----EAQLQEYK 968 T ++ + ++ + + ES I++++ L Y+ I+ +L E Q EY+ Sbjct: 1116 SQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYE 1175 Query: 969 NNIE---NLNMNVEELNKMNLELIDKHVQ--KQQTQSPDYTEQYINEINKLNALLKQKDE 1023 + I L + L + +L D++ Q KQ+ Q D + E K+ LL+ K+ Sbjct: 1176 SLISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKM--LLENKNH 1233 Query: 1024 EIIAL--------NQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSK 1075 E +A N ++N+ + ++ + L N + E R+ + K Sbjct: 1234 ETVAAEYKKLCGENDRLNHTYSQLLKETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLK 1293 Query: 1076 QHNEELQILVREQDDQIKELKETKLTFE 1103 + ++L I + ++Q + L + K E Sbjct: 1294 EQYQQLDITSTKLNNQCELLSQLKGNLE 1321 Score = 105 bits (253), Expect = 8e-21 Identities = 193/906 (21%), Positives = 386/906 (42%), Gaps = 77/906 (8%) Query: 689 KEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAE--KISELLAKINHEEQSK 746 ++ L + D + + +L+ ++ +D +LE+M E ++ + + + +S Sbjct: 246 RQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSA 305 Query: 747 IQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYL 806 + +DA ++E+ + ++ +ESE+S+YK R+ +E A +E E K D L Sbjct: 306 RMYRDELDA-LREKAVRVDKLESEVSRYKERLHDIEFYKARVE------ELKEDN--QVL 356 Query: 807 QEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQ 866 E + + ++L L + ++ +L ++E E +KK + L+EEN L+ Sbjct: 357 LETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLE 416 Query: 867 ISLS---DMQQHYNALVEKANRT-DLAESESTKYQTQLRDLESN-LKRITHEHQTLI--V 919 ++ D H +E+ +RT +L+E+ ++ +L S+ L ++ E+Q+L V Sbjct: 417 MAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTV 476 Query: 920 QKKKEIEDLEIEFN-TQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKN--------- 969 ++ + D +E N ++I ++ + L++K E + Q + LQ +N Sbjct: 477 EELRTTVD-SVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEK 535 Query: 970 -----NIENLNMNVEELNKMNLELIDKH----VQKQQTQSPDYTEQYINEINKLNALLKQ 1020 IE L N E K+ LE ++H V + +S E + +I K N +L + Sbjct: 536 AQLEKTIETLRENSERQIKI-LEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHE 594 Query: 1021 KDEEIIALNQKINNAQVSYMSMVSDYESK---LAQFTTKLENMEEEMQRVSKQLLDSKQH 1077 +E + KI + + Y+ K + +L ++E+E + + K++ + K Sbjct: 595 SIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKIT 654 Query: 1078 NEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXX 1137 E+++ L +E + +E ++ K T + + + S E D N++ Sbjct: 655 CEKIEALEQENSELERENRKLKKTLD-SFKNLTFQLESLEKENSQLDEENLELRRNVESL 713 Query: 1138 XXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQ---- 1193 +K+ + + E L+ + +L L+ + E L G D+ NQ Sbjct: 714 KCASMKMAQLQ---LENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQK 770 Query: 1194 ------EQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQRE 1247 ++I QL+S+L+ L EN L + EL+ S S ++Q E L +Q +Q E Sbjct: 771 TLENSNKKIQQLESELQDLEMENQTLQKNLEELKIS-SKRLEQLEKENKSL-EQETSQLE 828 Query: 1248 ADFQKTEHE---LRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQN--KLQDK 1302 D ++ E E LR Q ++ E+ ++V+ E+ NK ++ E ++ +L++ Sbjct: 829 KDKKQLEKENKRLRQQAEIKDTTLEE--NNVKIGNLEKENKTLSKEIGIYKESCVRLKEL 886 Query: 1303 EEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQM 1362 E+ + L ++ I + LR ++ EK+ + N+ Sbjct: 887 EKENKELVKRATIDIKTLVTLREDLVSEKLK--TQQMNNDLEKLTHELEKIGLNKERLLH 944 Query: 1363 QEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHE 1422 EQS + + + K S ++ EA++ E T+ + E+ Sbjct: 945 DEQSTDDSRYKLLESKLESTLKKSLEIKEE-KIAALEARLEESTNYNQQLRQELKTVKKN 1003 Query: 1423 YTITLTQRNDEFENVRQQLVEYEKRI--EDLTYEKESELAILRL-KMHENANHYETMQKE 1479 Y L QR DE +++V+ I ED +E+ES+ L K+ + E Sbjct: 1004 YE-ALKQRQDE-----ERMVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVERNNAT 1057 Query: 1480 SEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDE 1539 + E+ L +L T++ +L Q+ L + + +QT ++E TLN + Sbjct: 1058 LQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQ 1117 Query: 1540 ITNLQN 1545 T+L N Sbjct: 1118 STSLMN 1123 Score = 98.3 bits (234), Expect = 2e-18 Identities = 158/809 (19%), Positives = 336/809 (41%), Gaps = 68/809 (8%) Query: 749 TQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQE 808 +Q I+ ++ L+++ + E ++ I L E + ++ GS + Sbjct: 182 SQEDIEPLLKNMALHLKRLIDERDEHSETIIELSEERDGLHFLPHASSSAQSPCGSPGMK 241 Query: 809 KQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQIS 868 + ++ +++ + ++ L +QLL+ + E ++++ + + L +EN NL Sbjct: 242 RTESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSD 301 Query: 869 LSDMQQH---YNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEI 925 + + +AL EKA R D ESE ++Y+ +L D+E R V++ KE Sbjct: 302 ARSARMYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKAR---------VEELKED 352 Query: 926 EDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMN 985 + +E T +E + + ++K + + QL+A+L + + + +EEL + N Sbjct: 353 NQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEEN 412 Query: 986 LELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSD 1045 + L + QKQ + + +I++ + L + + +L ++N S + + Sbjct: 413 MTL--EMAQKQSMDESLHLGWELEQISRTSELSEAPQK---SLGHEVNELTSSRLLKLEM 467 Query: 1046 YESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMN 1105 L + +L + ++ + ++L ++ N+ L V +++I + K++ L N Sbjct: 468 ENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQS-LQNCQN 526 Query: 1106 IPK---TEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSA 1162 + K E + TIE + +++ + QE E Q S L+++S Sbjct: 527 LSKDLMKEKAQLEKTIETLRENSER-----------QIKILEQENEHLNQTVSSLRQRS- 574 Query: 1163 KLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRS 1222 +++ E ++ +E N L E I + SKL ++ E + + + Sbjct: 575 QISAE-----ARVKDIEKENKIL-------HESIKETSSKLSKIEFEKRQIKKELEHYKE 622 Query: 1223 SISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEE 1282 +R E+ E HL + QK L++ E+ L+ S + E Sbjct: 623 K-----GERAEEL-ENELHHLEKENELLQKKITNLKITCEKIEA-----LEQENSELERE 671 Query: 1283 TNKI-VTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILR-SEIEDEKVAFXXXXXX 1340 K+ T++ +L +L+ E+ L E+ ++ +E L+ + ++ ++ Sbjct: 672 NRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELE 731 Query: 1341 XXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEA 1400 +L + + E S ++ EN +L+K+ + D E Sbjct: 732 SEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEM 791 Query: 1401 KVLELTHQL-ELK-DSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESE 1458 + L L ELK S+ ++ + +L Q + E ++QL + KR+ K++ Sbjct: 792 ENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTT 851 Query: 1459 LAILRLKMHENANHYETMQKESEI-----ERVKLIEELNVKITESVSLN-KQVAELNKAL 1512 L +K+ +T+ KE I R+K +E+ N ++ + +++ K + L + L Sbjct: 852 LEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDL 911 Query: 1513 EEEVAKTNEMQTALE--NQEIEIVTLNDE 1539 E KT +M LE E+E + LN E Sbjct: 912 VSEKLKTQQMNNDLEKLTHELEKIGLNKE 940 Score = 93.5 bits (222), Expect = 4e-17 Identities = 178/885 (20%), Positives = 369/885 (41%), Gaps = 72/885 (8%) Query: 213 DTKQQMTKMQENFIAMEAEWKDEKQRLLKDIE--SKDVRISSLEEANKLLEAARFEISLE 270 +T ++ ++ Q + E E ++ L+ S + R+ +E+ NK+L + E S + Sbjct: 543 ETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSK 602 Query: 271 HSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIEL 330 SK+ E E+ + +E + E +I N+ +KIE Sbjct: 603 LSKI--EFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEA 660 Query: 331 LEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRK-SGRNTASKMKSPWSQL 389 LE N ++ + N++L+ L + + + S K+ S L R +K ++ Sbjct: 661 LEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKM 720 Query: 390 SSETLNQDTDKKINKNEIAK-LEMVIQSLNK-DLVDKEYVISEKDTXXXXXXXXXXGKDT 447 + L ++ + + K ++ K LE++ S K + ++ Y D + Sbjct: 721 AQLQL-ENKELESEKEQLKKGLELLKASFKKTERLEVSY--QGLDIENQRLQKTLENSNK 777 Query: 448 LIAQLQLEHQQ-HMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLK 506 I QL+ E Q ME +L N E++ +K EQL++E K Sbjct: 778 KIQQLESELQDLEMENQTL---QKNLEELKISSKRLEQLEKE----------------NK 818 Query: 507 SAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHH 566 S E++ +QL + K +++ ++K ++ +N K+ + KE L++E+ Sbjct: 819 SLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLE---ENNVKIGNLEKENKTLSKEIGI 875 Query: 567 LSQKVAELEE-EKGNLQL---HLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQ 622 + L+E EK N +L +D + + D+ + ++ + + K LE Sbjct: 876 YKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKI 935 Query: 623 KFDLVQELHILQQKYDEVEDKLADISQLQSDQVCS-EIKSVHLEEQIDALSASKKELALV 681 + + LH +Q D+ KL + S+L+S S EIK EE+I AL A +E Sbjct: 936 GLNKERLLHD-EQSTDDSRYKLLE-SKLESTLKKSLEIK----EEKIAALEARLEESTNY 989 Query: 682 IENLKLDKEQL---YGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAK 738 + L+ + + + Y +K ++++ + + ++N K E+ S E ELL K Sbjct: 990 NQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGEDN-----KWERESQETTRELL-K 1043 Query: 739 INHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERK 798 + + + A+ Q ++ +E++ + +++I L+ ++++ +L+ + Sbjct: 1044 VKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQ 1103 Query: 799 ADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQIL 858 +L Q S Q L+N+ A L+ +E + + E ++L+ L Sbjct: 1104 NAKL-------QVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSL 1156 Query: 859 LEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLI 918 +++++ L++ Y +L+ K A L D + L + + + L Sbjct: 1157 IKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKGQLEDLE 1216 Query: 919 VQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQ--LQEYKNNIENLNM 976 K E E + +E A KK+ E N Y L+ LQ N+++L + Sbjct: 1217 KMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLLKETEVLQTDHKNLKSL-L 1275 Query: 977 NVEELNKMNLELIDKHVQKQQTQSPDYTEQYINE----INKLNALLKQKDEEIIALNQ-- 1030 N +L + LE + K+Q Q D T +N +++L L++++ ++ Q Sbjct: 1276 NNSKLEQTRLE-AEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLEEENRHLLDQIQTL 1334 Query: 1031 KINNAQVSYMSMVSD--YESKLAQFTTKLENMEEEMQRVSKQLLD 1073 + N + +M S + + Q+ KL + + +++ ++++D Sbjct: 1335 MLQNRTLLEQNMESKDLFHVEQRQYIDKLNELRRQKEKLEEKIMD 1379 >UniRef50_Q4N897 Cluster: Putative uncharacterized protein; n=2; Theileria|Rep: Putative uncharacterized protein - Theileria parva Length = 1723 Score = 134 bits (324), Expect = 2e-29 Identities = 254/1266 (20%), Positives = 525/1266 (41%), Gaps = 103/1266 (8%) Query: 213 DTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHS 272 D + + + + F E++ +KQ L D S+LE + LE + + Sbjct: 225 DRNKDLNRKIKEFNQKNDEFEKQKQALDDQKSKYDSLNSNLEVRTRDLEREKDNYKRKTD 284 Query: 273 KLAQ---ELEQ--XXXXXXXXXXXXXXLAKQSIEPSCEEKTE-IEEKGSLEIANMTELTK 326 KLA+ EL++ LA Q E +++E +E + + + +L + Sbjct: 285 KLAEMELELQEDIKFYHKKQDELNAERLALQDKEKDYAKRSEDLESERTKILDKDRKLEE 344 Query: 327 KIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPW 386 ++ ++ + Q +++ + L T E+ V + KG L S +S R + + + Sbjct: 345 ELARIKEKEATLTQQHQKKDENL-TQREEALKVELETNKGL-LASIESQRTSLASEQREL 402 Query: 387 SQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKD 446 E + + + KL+ ++ + +V+ +SE+ T KD Sbjct: 403 ESKKQEQKLLEANINTETQRLEKLKQENEAAKEHMVNYGKFLSEETTKLNKIK-----KD 457 Query: 447 TLIAQLQL-EHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKL 505 A+ L E +Q ++ S E+ E ++Q+ L+ +++ E K N K L E+L Sbjct: 458 NEAAKAVLDEREQKLDEESQKIDQLKVENSKEAKRLQD-LQADIDKE-KLANTK-LSEQL 514 Query: 506 KSAEEQITQLNDEIDAANKNMIKVKSNHKLKL-KQMQKTI-DNFSKVSDSNKEIVRLTEE 563 +++ E + K+ + K+ L+ K +QK I +N + + K+ + E Sbjct: 515 NRERDELATKTQEQERL-KSEYESKNTQILETEKNLQKQISENETLAATLKKQEKDIEAE 573 Query: 564 LHHLSQKVAELEEEKGNLQLHLVDYDSGRMI--ESDVYKKMIEMENLAETRLKAISLLES 621 + +++ L +E+ N Q +++ Y + + S + K +E+ + + L+S Sbjct: 574 NEKIKKEIERLNQEERN-QAYILKYTAKQQSRKSSALLNKQKNLEDQIRLNTEKAASLQS 632 Query: 622 QKFDLVQELHILQQKYDEVEDKLADISQLQSDQV--CSEIKSVHLEEQIDALSASKKELA 679 Q+ +L ++ +Q + ++E + ++ Q + + ++ + Q AL K+E Sbjct: 633 QQQNLTEQTQRVQAELSDLERQRGEVQQKEEKLKLDTASVEEAKKKNQQRALDLKKQENT 692 Query: 680 L-VIEN-LKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLT---DKLEKMSAEKISE 734 + EN L + + Q K L+ D++ + KL + ++ T ++ +K EK E Sbjct: 693 VQERENKLLIAQAQNISKAKQLKKDQDVLNTKLAEHTEDVRRKTLEFEQRDKTLKEKELE 752 Query: 735 L---LAKINHEEQSKIQTQFGI-DAKIQERDLYIENIESELSKYKSRICRLEESIAVMED 790 LA++ + ++ + Q + DA+ Q R + ++E E K+R + E +A ++ Sbjct: 753 YQLKLAEVAEDHKTLFREQSLLNDAREQLRRDELAHMEKEKEAEKARQAKETELLATIK- 811 Query: 791 RRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKE 850 +++ + L +EKQK +E QE +L R HD + + E++ + + Sbjct: 812 -----QQETESLARIAEEKQKREAEILAQEQQLQQRRQA---HDDQIRRSQEELDRKIAD 863 Query: 851 LQKKNQILLEENQNLQISLSDMQQHYNALVEKANRT------DLAESESTKYQTQLRDLE 904 ++K+ E N Q + ++ A +A R E E K Q Q ++L Sbjct: 864 DKQKSAEAEERINNRQKEVDALKSDLEAKNAEAERLLSGHLHTKGELEKLKAQLQQQNLA 923 Query: 905 S-NLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQ 963 + L + E + Q+ E N +ES L+ + ++LEA Sbjct: 924 AQKLTKTLEEQNEAVKQENARATAANQEANRLLESNRAQAASLSRR-------ESELEAN 976 Query: 964 LQEYKNNIENLNMNVEELNKMNLELIDKHVQ-KQQTQSPDYTEQYINEINKLNALLKQKD 1022 + Y ++++ L +N L+ K + Q+ E+ ++E + L KQK Sbjct: 977 MDAYTIKLKSVQDEDARLTALNKTLLLKEESLGTRDQNVKDKERRVSE-REAEVLKKQKQ 1035 Query: 1023 EEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQ 1082 +E K + Q S++ E+ L Q ++ ++E +S++L D + EL Sbjct: 1036 QE------KTESEQNQRQSLLQSRENTLNQKESQQRTKDQEQSELSQKLADKQ---AELT 1086 Query: 1083 ILVREQDDQIKEL--KETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXX 1140 L + D K+L ++ +LT N + T + + AN + Sbjct: 1087 ALQSKLDQLQKDLDARQLQLTEAENAVRLRETKADETEKAQKNKANELLLEDEKVKRLGR 1146 Query: 1141 XLKVQEEEEFIQER------SVLQEQSAKL----NTELQECYT----KIIQLETLNTELT 1186 ++ + + IQE S L E+ AK+ +L+E T + +++ ++T+L Sbjct: 1147 EVEAKRQLAIIQENKNTQRSSELDEKQAKVEKLATDKLRELETIRTQQAEEIKNVSTQLK 1206 Query: 1187 GHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQR 1246 + ++ I +L +K E+L +N ++LS + SS S + + K L++ Sbjct: 1207 NKETELEQTIAKLNAKYEELKLDNKSVLSANRVMLSSAESNL--------IITKSELSRT 1258 Query: 1247 EADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHL 1306 ++D + EL + S E++ ++ + + ET Q+T N+L Sbjct: 1259 KSDLNTVKLELSTRTSELEAEKQKNSTLEAKNNELETQLSTAKSQLTEKGNELSQCVVRE 1318 Query: 1307 RNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQS 1366 L+ + +D+ +Q+++ +S+ DEK LR + + Q + Sbjct: 1319 TTLKSEKSDLESQLKV-KSDRYDEK---EKEYDTLKNLHKEAQSKLREKESAVSQCE--- 1371 Query: 1367 ILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTH---QLELKDSEIYQKTHEY 1423 + ++E+N QL+ + + ++ E KVLEL +LE K E+ + Sbjct: 1372 -VKLSEKNTQLESVTEQLGGKQKSLEQKTSELEGKVLELADKNLELERKQKEVLDRDARL 1430 Query: 1424 TITLTQ 1429 I TQ Sbjct: 1431 LIKETQ 1436 Score = 132 bits (319), Expect = 8e-29 Identities = 233/1151 (20%), Positives = 473/1151 (41%), Gaps = 101/1151 (8%) Query: 503 EKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTE 562 E LK E+ LN E+ N+ + + + MQK ++K D NK++ R + Sbjct: 186 EILKERLEKYVNLNRELHKKNEEAENLYNAY------MQK----YAKFYDRNKDLNRKIK 235 Query: 563 ELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQ 622 E + QK E E++K L YDS + S++ + ++E + + L Sbjct: 236 EFN---QKNDEFEKQKQALDDQKSKYDS---LNSNLEVRTRDLEREKDNYKRKTDKLAEM 289 Query: 623 KFDLVQELHILQQKYDEV-------EDKLADISQLQSDQVCSEIKSVHLEEQIDALSA-- 673 + +L +++ +K DE+ +DK D ++ D K + + +++ A Sbjct: 290 ELELQEDIKFYHKKQDELNAERLALQDKEKDYAKRSEDLESERTKILDKDRKLEEELARI 349 Query: 674 SKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKIS 733 +KE L ++ K D E L + L+ + E L + + L + ++ ++K Sbjct: 350 KEKEATLTQQHQKKD-ENLTQREEALKVELETNKGLLASIESQRTSLASEQRELESKKQE 408 Query: 734 ELL--AKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDR 791 + L A IN E Q + + +A + Y + + E +K E + AV+++R Sbjct: 409 QKLLEANINTETQRLEKLKQENEAAKEHMVNYGKFLSEETTKLNKIKKDNEAAKAVLDER 468 Query: 792 RYSLE---RKADQLGSYLQEKQKAYSEYT--IQEDELVN-RLAVLMDHDR-VVEKQLLEI 844 L+ +K DQL ++ K + I +++L N +L+ ++ +R + + E Sbjct: 469 EQKLDEESQKIDQLKVENSKEAKRLQDLQADIDKEKLANTKLSEQLNRERDELATKTQEQ 528 Query: 845 EHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQ-LRDL 903 E E + KN +LE +NLQ +S+ + A ++K + AE+E K + + L Sbjct: 529 ERLKSEYESKNTQILETEKNLQKQISE-NETLAATLKKQEKDIEAENEKIKKEIERLNQE 587 Query: 904 ESN---LKRITHEHQT----LIVQKKKEIEDLEIEFNTQIESAIRDKKV-LNEKYEKNIE 955 E N + + T + Q+ ++ K+K +ED +I NT+ ++++ ++ L E+ ++ Sbjct: 588 ERNQAYILKYTAKQQSRKSSALLNKQKNLED-QIRLNTEKAASLQSQQQNLTEQTQRVQA 646 Query: 956 YVTQLEAQLQEYKNNIENLNMN---VEELNKMNLE-LIDKHVQKQQTQSPDYTEQYINEI 1011 ++ LE Q E + E L ++ VEE K N + +D Q+ Q + Sbjct: 647 ELSDLERQRGEVQQKEEKLKLDTASVEEAKKKNQQRALDLKKQENTVQERENKLLIAQAQ 706 Query: 1012 NKLNALLKQKDEEIIALN-----QKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQR 1066 N A +KD++++ + + + + + K ++ KL + E+ + Sbjct: 707 NISKAKQLKKDQDVLNTKLAEHTEDVRRKTLEFEQRDKTLKEKELEYQLKLAEVAEDHKT 766 Query: 1067 VSKQ---LLDSKQH--NEELQILVREQD-DQIKELKETKLTFEMNIPKTEGMI-ISSTIE 1119 + ++ L D+++ +EL + +E++ ++ ++ KET+L + +TE + I+ + Sbjct: 767 LFREQSLLNDAREQLRRDELAHMEKEKEAEKARQAKETELLATIKQQETESLARIAEEKQ 826 Query: 1120 PMSDD--ANNVDXXXXXXXXXXXXLKVQEE--EEFIQERSVLQEQSAKLNTELQECYTKI 1175 + A + QEE + ++ E ++N +E Sbjct: 827 KREAEILAQEQQLQQRRQAHDDQIRRSQEELDRKIADDKQKSAEAEERINNRQKEVDALK 886 Query: 1176 IQLETLNTE----LTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSI---SSAV 1228 LE N E L+GH + + ++ +LK++L+Q N L T+ E ++ ++ Sbjct: 887 SDLEAKNAEAERLLSGH-LHTKGELEKLKAQLQQQNLAAQKLTKTLEEQNEAVKQENARA 945 Query: 1229 DQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVT 1288 E L + + AQ A + E EL + A+ K + + D T ++ Sbjct: 946 TAANQEANRLLESNRAQA-ASLSRRESELEANMDAYTIKLKSVQDEDARLTALNKTLLLK 1004 Query: 1289 MEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXX 1348 E + + ++DKE R + E+ A+V+ + + + + E E+ Sbjct: 1005 EESLGTRDQNVKDKE---RRVSEREAEVLKK-QKQQEKTESEQNQRQSLLQSRENTLNQK 1060 Query: 1349 XXDLRTENQSYKQMQEQ------SILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKV 1402 RT++Q ++ ++ + + + QL+K V E K Sbjct: 1061 ESQQRTKDQEQSELSQKLADKQAELTALQSKLDQLQKDLDARQLQLTEAENAVRLRETKA 1120 Query: 1403 LEL-------THQLELKDSEIYQKTHEYT----ITLTQRNDEFENVRQQLVEYEKRIEDL 1451 E ++L L+D ++ + E + + Q N + +L E + ++E L Sbjct: 1121 DETEKAQKNKANELLLEDEKVKRLGREVEAKRQLAIIQENKNTQR-SSELDEKQAKVEKL 1179 Query: 1452 TYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKA 1511 +K EL +R + E + T K E E + I +LN K E NK V N+ Sbjct: 1180 ATDKLRELETIRTQQAEEIKNVSTQLKNKETELEQTIAKLNAKYEELKLDNKSVLSANRV 1239 Query: 1512 LEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQ 1571 + + E + E+ + L+ R S + +K + + K E Sbjct: 1240 M----LSSAESNLIITKSELSRTKSDLNTVKLELSTRTSELEAEKQKNSTLEAKNNELET 1295 Query: 1572 LDNTMNKELLD 1582 +T +L + Sbjct: 1296 QLSTAKSQLTE 1306 Score = 124 bits (300), Expect = 2e-26 Identities = 224/1182 (18%), Positives = 490/1182 (41%), Gaps = 126/1182 (10%) Query: 475 VNEIAKVQEQLKQELNDEIKDVNVK-DLIEKLKSA----EEQITQLNDEIDAANKNMIKV 529 + + AK ++ K +LN +IK+ N K D EK K A + + LN ++ +++ + Sbjct: 217 MQKYAKFYDRNK-DLNRKIKEFNQKNDEFEKQKQALDDQKSKYDSLNSNLEVRTRDLERE 275 Query: 530 KSNHKLKLK-------QMQKTIDNFSKVSDS-NKEIVRLTEELHHLSQKVAELEEEKGNL 581 K N+K K ++Q+ I + K D N E + L ++ +++ +LE E+ + Sbjct: 276 KDNYKRKTDKLAEMELELQEDIKFYHKKQDELNAERLALQDKEKDYAKRSEDLESERTKI 335 Query: 582 --QLHLVDYDSGRMIESDV---YKKMIEMENLA----------ETRLKAISLLESQKFDL 626 + ++ + R+ E + + + ENL ET ++ +ESQ+ L Sbjct: 336 LDKDRKLEEELARIKEKEATLTQQHQKKDENLTQREEALKVELETNKGLLASIESQRTSL 395 Query: 627 VQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASK--KELALVIEN 684 E L+ K + E KL + + Q ++K + + ++ K E + Sbjct: 396 ASEQRELESK--KQEQKLLEANINTETQRLEKLKQENEAAKEHMVNYGKFLSEETTKLNK 453 Query: 685 LKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKL---------EKMSAEKISEL 735 +K D E + + E ++ K+ EN +L EK++ K+SE Sbjct: 454 IKKDNEAAKAVLDEREQKLDEESQKIDQLKVENSKEAKRLQDLQADIDKEKLANTKLSEQ 513 Query: 736 LAKINHEEQSKIQTQFGIDAKIQERDLYI----ENIESELSKYKSRICRLEESIAVMEDR 791 L + E +K Q Q + ++ + ++ I +N++ ++S+ ++ L++ +E Sbjct: 514 LNRERDELATKTQEQERLKSEYESKNTQILETEKNLQKQISENETLAATLKKQEKDIEAE 573 Query: 792 RYSLERKADQLGSYLQEKQKAYS-EYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKE 850 ++++ ++L +E+ +AY +YT ++ + + L++ + +E Q+ + Sbjct: 574 NEKIKKEIERLNQ--EERNQAYILKYTAKQQS--RKSSALLNKQKNLEDQIRLNTEKAAS 629 Query: 851 LQKKNQILLEENQNLQISLSDMQQHYNALVEKANRT--DLAESESTKYQTQLRDLESNLK 908 LQ + Q L E+ Q +Q LSD+++ + +K + D A E K + Q R L+ + Sbjct: 630 LQSQQQNLTEQTQRVQAELSDLERQRGEVQQKEEKLKLDTASVEEAKKKNQQRALDLKKQ 689 Query: 909 RIT---HEHQTLIVQ-----KKKEIEDLEIEFNTQIESAIRD--KKVLNEKY------EK 952 T E++ LI Q K K+++ + NT++ D +K L + EK Sbjct: 690 ENTVQERENKLLIAQAQNISKAKQLKKDQDVLNTKLAEHTEDVRRKTLEFEQRDKTLKEK 749 Query: 953 NIEYVTQLEAQLQEYKNNIEN---LNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYIN 1009 +EY +L +++K LN E+L + L ++K + ++ + TE Sbjct: 750 ELEYQLKLAEVAEDHKTLFREQSLLNDAREQLRRDELAHMEKEKEAEKARQAKETE---- 805 Query: 1010 EINKLNALLKQKDEEIIA-LNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVS 1068 L A +KQ++ E +A + ++ + ++ + + ++ +EE+ R Sbjct: 806 ----LLATIKQQETESLARIAEEKQKREAEILAQEQQLQQRRQAHDDQIRRSQEELDR-- 859 Query: 1069 KQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNV 1128 ++ D KQ + E + + + ++ LK E + E ++ + Sbjct: 860 -KIADDKQKSAEAEERINNRQKEVDALKSD---LEAKNAEAERLLSGHLHTKGELEKLKA 915 Query: 1129 DXXXXXXXXXXXXLKVQEEEEFI-QERSVLQEQSAKLNTELQECYTKIIQLETLNTELTG 1187 ++E+ E + QE + + + N L+ + L +EL Sbjct: 916 QLQQQNLAAQKLTKTLEEQNEAVKQENARATAANQEANRLLESNRAQAASLSRRESELEA 975 Query: 1188 HDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQRE 1247 + ++ ++ + +L N LL L + + D+ ++ +++RE Sbjct: 976 NMDAYTIKLKSVQDEDARLTALNKTLLLKEESLGTRDQNVKDK---------ERRVSERE 1026 Query: 1248 ADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTS-LQNKLQDKEEHL 1306 A+ K + + + + + +++ + LL S +++ ++ ++ T +Q S L KL DK+ L Sbjct: 1027 AEVLKKQKQ-QEKTESEQNQRQSLLQSRENTLNQKESQQRTKDQEQSELSQKLADKQAEL 1085 Query: 1307 RNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQS 1366 LQ K + ++ + ++ + + A + + ++++ Sbjct: 1086 TALQSKLDQLQKDLDARQLQLTEAENAVRLRETKADETEKA-----QKNKANELLLEDEK 1140 Query: 1367 ILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTIT 1426 + + E ++ + +++ +AKV +L K E Sbjct: 1141 VKRLGREVEAKRQLAIIQENKNTQRSSELDEKQAKVEKLATD----------KLRELETI 1190 Query: 1427 LTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRL--KMHENANHYETMQKESEI-- 1482 TQ+ +E +NV QL E +E + ++ L+L K +AN ES + Sbjct: 1191 RTQQAEEIKNVSTQLKNKETELEQTIAKLNAKYEELKLDNKSVLSANRVMLSSAESNLII 1250 Query: 1483 ---ERVKLIEELN-VKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLND 1538 E + +LN VK+ S ++ AE K E AK NE++T L + ++ + Sbjct: 1251 TKSELSRTKSDLNTVKLELSTRTSELEAEKQKNSTLE-AKNNELETQLSTAKSQLTEKGN 1309 Query: 1539 EITNL---QNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMN 1577 E++ + +++ S ++ + SD ++++ D N Sbjct: 1310 ELSQCVVRETTLKSEKSDLESQLKVKSDRYDEKEKEYDTLKN 1351 Score = 113 bits (273), Expect = 3e-23 Identities = 207/1129 (18%), Positives = 476/1129 (42%), Gaps = 83/1129 (7%) Query: 477 EIAKVQEQLKQELNDEI-KDVNVKDLIEKLKSAEEQITQLNDEID---AANKNMIKVK-- 530 + AK E L+ E + KD +++ + ++K E +TQ + + D + +KV+ Sbjct: 320 DYAKRSEDLESERTKILDKDRKLEEELARIKEKEATLTQQHQKKDENLTQREEALKVELE 379 Query: 531 SNHKL--KLKQMQKTIDNFSKVSDSNKEIVRLTE-ELHHLSQKVAELEEEKGNLQLHLVD 587 +N L ++ + ++ + + +S K+ +L E ++ +Q++ +L++E + H+V+ Sbjct: 380 TNKGLLASIESQRTSLASEQRELESKKQEQKLLEANINTETQRLEKLKQENEAAKEHMVN 439 Query: 588 YDSGRMIESDVYK-KMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLAD 646 Y G+ + + K I+ +N A KA+ QK D +E + Q E + Sbjct: 440 Y--GKFLSEETTKLNKIKKDNEAA---KAVLDEREQKLD--EESQKIDQLKVENSKEAKR 492 Query: 647 ISQLQSDQVCSEIKSVHLEEQI----DALSASKKELALVIENLKLDKEQLYGTIKDLE-- 700 + LQ+D ++ + L EQ+ D L+ +E + + Q+ T K+L+ Sbjct: 493 LQDLQADIDKEKLANTKLSEQLNRERDELATKTQEQERLKSEYESKNTQILETEKNLQKQ 552 Query: 701 -NDKEDI---MNKLQNYIQ-ENMDLTDKLEKMSAEKISEL-LAKINHEEQSK-----IQT 749 ++ E + + K + I+ EN + ++E+++ E+ ++ + K ++QS+ + Sbjct: 553 ISENETLAATLKKQEKDIEAENEKIKKEIERLNQEERNQAYILKYTAKQQSRKSSALLNK 612 Query: 750 QFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLG---SYL 806 Q ++ +I+ +++S+ + R++ ++ +E +R +++K ++L + + Sbjct: 613 QKNLEDQIRLNTEKAASLQSQQQNLTEQTQRVQAELSDLERQRGEVQQKEEKLKLDTASV 672 Query: 807 QEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQ-LLEIEHENKELQKKNQILLEENQNL 865 +E +K + + + N + + + + Q + + + K+ N L E +++ Sbjct: 673 EEAKKKNQQRALDLKKQENTVQERENKLLIAQAQNISKAKQLKKDQDVLNTKLAEHTEDV 732 Query: 866 QISLSDMQQHYNALVEKA-----NRTDLAESESTKYQTQ--LRDLESNLKRITHEHQTLI 918 + + +Q L EK ++AE T ++ Q L D L+R H Sbjct: 733 RRKTLEFEQRDKTLKEKELEYQLKLAEVAEDHKTLFREQSLLNDAREQLRRDELAH---- 788 Query: 919 VQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNV 978 ++K+KE E T++ + I+ ++ E + E + EA++ + ++ Sbjct: 789 MEKEKEAEKARQAKETELLATIKQQET--ESLARIAEEKQKREAEILAQEQQLQQRRQAH 846 Query: 979 EELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNAL-----LKQKDEEIIALNQKIN 1033 ++ + + E +D+ + + +S + E+ N +++AL K + E + Sbjct: 847 DDQIRRSQEELDRKIADDKQKSAEAEERINNRQKEVDALKSDLEAKNAEAERLLSGHLHT 906 Query: 1034 NAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIK 1093 ++ + ++ AQ TK +EE+ + V ++ + N+E L+ Q Sbjct: 907 KGELEKLKAQLQQQNLAAQKLTK--TLEEQNEAVKQENARATAANQEANRLLESNRAQAA 964 Query: 1094 ELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQE 1153 L + E N+ + S E A N V+++E + E Sbjct: 965 SLSRRESELEANMDAYTIKLKSVQDEDARLTALNKTLLLKEESLGTRDQNVKDKERRVSE 1024 Query: 1154 RS--VLQEQSAKLNTELQECYTKII---QLETLNTELTGHDVVNQEQINQLKSKLEQLNT 1208 R VL++Q + TE ++ + + + TLN + + +QEQ ++L KL Sbjct: 1025 REAEVLKKQKQQEKTESEQNQRQSLLQSRENTLNQKESQQRTKDQEQ-SELSQKLADKQA 1083 Query: 1209 ENDNLLSTVAELRSSISSAVDQRGFEIAELWKQ-HLAQREAD-FQKTEHELRVQLSAFES 1266 E L S + +L+ + D R ++ E L + +AD +K + +L + Sbjct: 1084 ELTALQSKLDQLQKDL----DARQLQLTEAENAVRLRETKADETEKAQKNKANELLLEDE 1139 Query: 1267 KYEQLLDSVQSSTQ----EETNKIVTMEQVTSLQNKLQD-KEEHLRNLQEKYADVINQIE 1321 K ++L V++ Q +E ++ Q K++ + LR L+ +I+ Sbjct: 1140 KVKRLGREVEAKRQLAIIQENKNTQRSSELDEKQAKVEKLATDKLRELETIRTQQAEEIK 1199 Query: 1322 ILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSS 1381 + +++++++ D ++ + + M + N+ ++L ++ Sbjct: 1200 NVSTQLKNKETELEQTIAKLNAKYEELKLDNKSVLSANRVMLSSAESNLIITKSELSRTK 1259 Query: 1382 XXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQL 1441 R ++ EA+ + LE K++E+ + LT++ +E Q Sbjct: 1260 SDLNTVKLELSTRTSELEAEK-QKNSTLEAKNNELETQLSTAKSQLTEKGNELS----QC 1314 Query: 1442 VEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSL 1501 V E ++ + ES+L + + E Y+T++ + + KL E+ + V L Sbjct: 1315 VVRETTLKSEKSDLESQLKVKSDRYDEKEKEYDTLKNLHKEAQSKLREKESAVSQCEVKL 1374 Query: 1502 NKQVAELNKALEEEVAKTNEMQ---TALENQEIEIVTLNDEITNLQNMV 1547 +++ +L E+ K ++ + LE + +E+ N E+ Q V Sbjct: 1375 SEKNTQLESVTEQLGGKQKSLEQKTSELEGKVLELADKNLELERKQKEV 1423 Score = 91.1 bits (216), Expect = 2e-16 Identities = 175/946 (18%), Positives = 384/946 (40%), Gaps = 100/946 (10%) Query: 700 ENDKEDIMNKLQNYIQENMDLTDKLEKMSA--EKISELLAKINHEEQSKIQTQFGIDAKI 757 + ++E + +L+ Y+ N +L K E+ + AK + + + K Sbjct: 182 KTEQEILKERLEKYVNLNRELHKKNEEAENLYNAYMQKYAKFYDRNKDLNRKIKEFNQKN 241 Query: 758 QERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYT 817 E + + ++ + SKY S LE +E + + +RK D+L E Q+ Y Sbjct: 242 DEFEKQKQALDDQKSKYDSLNSNLEVRTRDLEREKDNYKRKTDKLAEMELELQEDIKFYH 301 Query: 818 IQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDM-QQHY 876 ++DEL L D ++ K+ ++E E ++ K++ L EE ++ + + QQH Sbjct: 302 KKQDELNAERLALQDKEKDYAKRSEDLESERTKILDKDRKLEEELARIKEKEATLTQQHQ 361 Query: 877 NALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQ- 935 R + + E + L +ES + E + L KK+E + LE NT+ Sbjct: 362 KKDENLTQREEALKVELETNKGLLASIESQRTSLASEQREL-ESKKQEQKLLEANINTET 420 Query: 936 --IESAIRDKKVLNE---KYEKNI-EYVTQL----------EAQLQEYKNNIENLNMNVE 979 +E ++ + E Y K + E T+L +A L E + ++ + ++ Sbjct: 421 QRLEKLKQENEAAKEHMVNYGKFLSEETTKLNKIKKDNEAAKAVLDEREQKLDEESQKID 480 Query: 980 ELNKMN------LELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKD---EEIIALNQ 1030 +L N L+ + + K++ + +EQ E ++L ++++ E + N Sbjct: 481 QLKVENSKEAKRLQDLQADIDKEKLANTKLSEQLNRERDELATKTQEQERLKSEYESKNT 540 Query: 1031 KINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQL--LDSKQHNEE--LQILVR 1086 +I + + +S+ E+ A + +++E E +++ K++ L+ ++ N+ L+ + Sbjct: 541 QILETEKNLQKQISENETLAATLKKQEKDIEAENEKIKKEIERLNQEERNQAYILKYTAK 600 Query: 1087 EQDDQIKEL--KETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKV 1144 +Q + L K+ L ++ + + + S + +++ V ++ Sbjct: 601 QQSRKSSALLNKQKNLEDQIRLNTEKAASLQSQQQNLTEQTQRVQAELSDLERQRGEVQQ 660 Query: 1145 QEEE--------------------EFIQERSVLQEQSAKLNTELQECYTKIIQL----ET 1180 +EE+ + ++ + +QE+ KL + +K QL + Sbjct: 661 KEEKLKLDTASVEEAKKKNQQRALDLKKQENTVQERENKLLIAQAQNISKAKQLKKDQDV 720 Query: 1181 LNTELTGH--DVVNQE-QINQLKSKLEQLNTENDNLLSTVAE-------LRSSISSAVDQ 1230 LNT+L H DV + + Q L++ E L+ VAE +S ++ A +Q Sbjct: 721 LNTKLAEHTEDVRRKTLEFEQRDKTLKEKELEYQLKLAEVAEDHKTLFREQSLLNDAREQ 780 Query: 1231 -RGFEIAELWKQHLAQ-----READF------QKTEHELRVQLSAFESKYEQLLDSVQSS 1278 R E+A + K+ A+ +E + Q+TE R+ + + E L Q Sbjct: 781 LRRDELAHMEKEKEAEKARQAKETELLATIKQQETESLARIAEEKQKREAEILAQEQQLQ 840 Query: 1279 TQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXX 1338 + + + L K+ D ++ +E+ + +++ L+S++E K A Sbjct: 841 QRRQAHDDQIRRSQEELDRKIADDKQKSAEAEERINNRQKEVDALKSDLE-AKNAEAERL 899 Query: 1339 XXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDA 1398 L+ + Q ++ + E+N +K+ + + Sbjct: 900 LSGHLHTKGELEKLKAQLQQQNLAAQKLTKTLEEQNEAVKQENARATAANQEANRLLESN 959 Query: 1399 EAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENV----------RQQLVEYEKRI 1448 A+ L+ ++SE+ YTI L DE + + L ++ + Sbjct: 960 RAQAASLSR----RESELEANMDAYTIKLKSVQDEDARLTALNKTLLLKEESLGTRDQNV 1015 Query: 1449 EDLTYE-KESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAE 1507 +D E E +L+ + + E Q++S ++ + LN K ++ + +++ +E Sbjct: 1016 KDKERRVSEREAEVLKKQKQQEKTESEQNQRQSLLQSRE--NTLNQKESQQRTKDQEQSE 1073 Query: 1508 LNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSK 1553 L++ L ++ A+ +Q+ L+ + ++ ++T +N VR +K Sbjct: 1074 LSQKLADKQAELTALQSKLDQLQKDLDARQLQLTEAENAVRLRETK 1119 >UniRef50_A2ESN0 Cluster: Viral A-type inclusion protein, putative; n=1; Trichomonas vaginalis G3|Rep: Viral A-type inclusion protein, putative - Trichomonas vaginalis G3 Length = 2345 Score = 134 bits (324), Expect = 2e-29 Identities = 297/1564 (18%), Positives = 633/1564 (40%), Gaps = 103/1564 (6%) Query: 61 LENAALVSKRIKEHRKATAELLGRPFVPGISESLANTLKQKEILMEKIKQYKELSKRSST 120 + NA SK E K +LL + +++ ++ KQ + L E+ KE + +++ Sbjct: 509 MSNALEKSKNDVEAAKRENDLLQKK----LAQITSDLQKQIDALEEENGDLKEEANKANA 564 Query: 121 TIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKIN 180 + QL D + + N +K K+ ET DL + Sbjct: 565 DCAKAKEQLNKAIADTKK-QLADKEQTHEELLKNSNE-EKQGIKKKLNETAN-DLAKTKE 621 Query: 181 EKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFI-AMEAEWKDEKQRL 239 + Q+ E K+K T + QQ + +++ AM A L Sbjct: 622 QLQQMAEEKDK-TQSKLDAEEGKRKNAENQLKLLSQQNSDLKDLIEQAMHAIGATNNDDL 680 Query: 240 LKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQS 299 LK I++ S+L++A + + ++ E+ + +A E + +A + Sbjct: 681 LKAIQNNASAQSTLDKACRNIGVSQAELPQTLTNIANE-RKHMMSTLQVPEKGGDIASKV 739 Query: 300 IEPSCEEKTEIEEKGSLEIANMT-ELTKKIELLEH---LNCQIRQTNKELENKLATMGTE 355 + + K +EE +L+ N E + L ++Q N+ E+++ Sbjct: 740 DSLANQYKENLEELNNLKAYNKKFGKAFNFEFNPNETTLKNAVKQGNQAHEDRVCAQEIV 799 Query: 356 SKAVSSPSKKGSPLISRKSGRNTASK-MKSPWSQLSSETLNQDTDKKINKNEIAKLEMVI 414 +A +P+ + + NT K + + ++ + K +++I +L + Sbjct: 800 GRAQKLGYIGDNPIEASEYITNTVKKQLGDELDRAKNDNNAKQAQIKGMQDKIDELSEKL 859 Query: 415 QSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQL---QLEHQQHMEGP--SLIH-V 468 + K DK+ + K K IA+ + E + +EG ++I + Sbjct: 860 DTATKTSDDKDKDYAAKMKAAEKQIKELQAKADDIAKEFTDEAESKNQLEGKLKAIIGAL 919 Query: 469 GTNTEDVN-EIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLND--EIDAANKN 525 G + D + A++ Q +E ++ + + V + A + + LN+ ++ + ++ Sbjct: 920 GVSDPDTGLQAAQMSFQKAKEFDENLAIIKVDE-----DQAVDTVANLNNKGQVLSQIQD 974 Query: 526 MIKVKSNHKLKLKQMQKTIDNFSKVSD--SNKEIVRLTEELHHLSQKVAELEEEKGNLQL 583 MI ++ K+ + ++K +D +KV V L E + + +L+ E N Q Sbjct: 975 MISTPNSDKV-VPAIKKLVDERNKVEQFLETNGAVPLPEAVEDVVMNEKKLQFELENAQN 1033 Query: 584 HLVD-YDSGRMI----------ESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHI 632 + YD+ MI +S ++K + + A+ AI + Q L Sbjct: 1034 IIKKFYDANGMIMPQPGASPTKKSQIFKDIEKQREQAQENRDAIIDVLEQAHKLGYGASS 1093 Query: 633 LQQKYDEVEDKLADISQLQSD---QVCSEIKSVHLEEQIDALSASKKELALV-IENLKLD 688 L + + +++ + + + D Q S+ K L+E I+ L + +LA + KL Sbjct: 1094 LDEAVEAIKNAVQKDEKKKQDALQQQFSQEKDALLDE-IEELQSQNAKLADENAQQQKLL 1152 Query: 689 KEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQ 748 +Q + D + + ++ NK +N N+ +K + A+K+ ++ A++ +E++ Sbjct: 1153 NDQ-EKALADADEEISELQNKAENQ-SSNIASKNKENEAIAKKLEDIKAELQNEKKEHEA 1210 Query: 749 TQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQE 808 + D K+ +DL + + E + LEE I + + + ++ D L L Sbjct: 1211 DKAAADKKL--KDLQQQKAQQE-QDFAEEKADLEEQIQNLTKQNENAKKDNDALAGKLAA 1267 Query: 809 KQKAYSEYTIQED--ELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQ 866 ++ + TI +D E+ N + D + +++ E +L+ K + L Q Sbjct: 1268 TEEELKQ-TIAKDNEEIENAKKTINDLGKQAKQKDKEAASTVTDLEDKIEDLQNNLNQSQ 1326 Query: 867 ISLSDMQQHYNALVEKANRTDLA-ESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEI 925 ++ + AL E+ N+ D E+E K Q QL+ L+ + ++ L +K +EI Sbjct: 1327 RDNDNLNKKVAALQEEQNQKDQQYEAELEKLQNQLKQLQQQKAQQEQDNNKLNDEKDEEI 1386 Query: 926 EDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMN 985 + L N +IE R N+ +K E Q + + + N I NLN +E L K N Sbjct: 1387 QQL----NKEIEEMQR----AND--QKIREMNKQAKQKDDDNNNQIMNLNDQIEALKK-N 1435 Query: 986 LELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSD 1045 L K + + + E+ N I K N ++ ++I LN++ + S + + Sbjct: 1436 LSQAQKDNEGLNKKLAEKEEELSNVIAKDNDEIENAKKQINDLNKQNKQKEKDSNSQIEE 1495 Query: 1046 YESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIK-ELKETKLTFEM 1104 + ++ L ++ +++ K+L D + E + DQ+ +L E + Sbjct: 1496 LKDQIDVLENTLAQVQRDLETTQKKLADKEAELAETIAKGNAEQDQLNNQLNELNKQGKQ 1555 Query: 1105 NIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKL 1164 K +S E + ++ L+ ++EE L + AK Sbjct: 1556 K-DKENAAAMSQAKEQIEQLQAALNQAQKDNDNANKKLQAKDEE--------LNQTIAKD 1606 Query: 1165 NTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSI 1224 N EL++ + Q LN + D N +QI L+ ++ +L + LL L + Sbjct: 1607 NDELEK---QRKQYNDLNKQKQQKDKENADQIQNLQDQIAKLQKQGAQLLKDNENLGKKL 1663 Query: 1225 SSAVDQRGFEIAELWKQHLAQRE--ADFQK-TEHELRVQLSAFESKYEQLLDSVQSSTQE 1281 + ++ +A+ ++ Q++ +D K ++ + R + EQ+ D +S Q Sbjct: 1664 NEKEEELKQTVAKDTEEMEKQKKTISDLNKQSKQKDRENGNQVMDLQEQIEDLQKSLAQA 1723 Query: 1282 ETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXX 1341 + + V +++ +LQN+ + + + ++ E + I + ++++E EK Sbjct: 1724 QRDNEVLGKKIGNLQNEQEQENQEHKDAIENLENQIKALNQQKNQVEQEKNKQKEQQDDE 1783 Query: 1342 XXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAK 1401 DL+ + + + +Q + ++N + A L++ + NDAE K Sbjct: 1784 IEQLKQQIEDLQKQAEINDKKHQQQVASLNGDVAGLQEK-------LEAMTQQKNDAEHK 1836 Query: 1402 VLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAI 1461 + L+ + E E + N ++++++ E ++ E L E Sbjct: 1837 AAQTKEDLDKVNQENEANKQEKDQLQKKLNQTAGDLQKRVKELQEENETLHEEAVKNNEQ 1896 Query: 1462 LRLKMHENANHYETMQKESE-IERVKLIEELNVKITESVSLNKQVAEL---NKALEEEVA 1517 L+ + + + ++E + + R+ +ELN E+ L +Q+A++ K E ++A Sbjct: 1897 LQRALSDVKKQLKEKEREHDNLSRIS-GDELNDLKRENEGLKEQLAKVTEDKKEAERQLA 1955 Query: 1518 KTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMN 1577 +TN + LE + L D+ ++ + + +K +K ++ +D K+ + +L+ Sbjct: 1956 QTNNEKKDLEE---KFQKLADDKKDVDDKL----AKTEKELAKVNDEKKEAEGKLEELGK 2008 Query: 1578 KELL 1581 K+ L Sbjct: 2009 KDKL 2012 Score = 126 bits (305), Expect = 4e-27 Identities = 275/1496 (18%), Positives = 605/1496 (40%), Gaps = 156/1496 (10%) Query: 147 LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXX 206 L ++K A ++ + ++ LQ K++ + +EA K + Sbjct: 62 LKEITQQKQIAEQQATSQIASLNDQVMQLQGKLDNLSKQLEASQKKLSQTTSELGGELEQ 121 Query: 207 XXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFE 266 + +Q+M +Q DEK ++ + + ++++ N L +++ Sbjct: 122 TKENNANLEQKMKDLQNQNAKNAQALNDEKDQIQGKLNETMKELDNVKQQNDSLN-KKYD 180 Query: 267 ISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTK 326 +E+ L ELE +Q ++ + +KT E+ K Sbjct: 181 TDVEN--LKNELEATKALNGQN--------EQKLKDANAQKTAAEQ-------------K 217 Query: 327 KIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPW 386 ++L + Q Q +ELEN T +K ++ K + K+ + ++ Sbjct: 218 LVQLQQQYEDQTAQLKQELENNKRDNDTNAKKQATLQKDLENQL--KNANDEIETLEQRN 275 Query: 387 SQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKD 446 L+++ N D N + I +LE ++ L KD + KD Sbjct: 276 KDLTAQKQNNDNK---NASRINELEDEVEKLTKDCETLKIKNGSLKKKLQAASQDNMNKD 332 Query: 447 TLIAQLQLEHQQHMEGPSLIH----VGTNTEDVN---EIAKVQEQLKQE------LNDEI 493 + QL+ E++Q M+ + + TN E N +I ++Q+QL Q LN I Sbjct: 333 EAMKQLRDENEQKMKEMNKQNKQKEQETNAEFQNLHDQIEQLQKQLAQSQRENDTLNKRI 392 Query: 494 ------KDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNF 547 K K+ E+L+ E Q+ QL + + + K K + L++ Q+ +D Sbjct: 393 NNLQGDKATQDKEYAEELEKLENQLKQLQQQKQQTEQELSKQKEQNAQDLQKAQEQMDEM 452 Query: 548 SKVSDSN-----KEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYD-SGRMIESDVYKK 601 K +D+N + L EEL Q++ E++ +L + +D+ Sbjct: 453 QKQNDANDKKNQAQAKALEEELEQAKQQLKNQEQKINDLNAQKTQVEQKAAQNNTDMSNA 512 Query: 602 MIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQ--LQSDQVCSEI 659 + + +N E + LL+ + L Q LQ++ D +E++ D+ + +++ C++ Sbjct: 513 LEKSKNDVEAAKRENDLLQKK---LAQITSDLQKQIDALEEENGDLKEEANKANADCAKA 569 Query: 660 KSVHLEEQIDALSASKKELALVIENLKLDKEQLY-GTIKDLENDKEDIMNKLQNYIQENM 718 K E+ A++ +KK+LA DKEQ + +K+ +K+ I KL + Sbjct: 570 K----EQLNKAIADTKKQLA--------DKEQTHEELLKNSNEEKQGIKKKLNETANDLA 617 Query: 719 DLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRI 778 ++L++M+ EK + QSK+ + G K + + ++ + + S K I Sbjct: 618 KTKEQLQQMAEEK---------DKTQSKLDAEEG---KRKNAENQLKLLSQQNSDLKDLI 665 Query: 779 CRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVE 838 + +I + L + S KA + + EL L + + + + Sbjct: 666 EQAMHAIGATNND--DLLKAIQNNASAQSTLDKACRNIGVSQAELPQTLTNIANERKHMM 723 Query: 839 KQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQT 898 L E K + + + +NL+ L++++ YN KA + +E+T Sbjct: 724 STLQVPEKGGDIASKVDSLANQYKENLE-ELNNLKA-YNKKFGKAFNFEFNPNETTLKNA 781 Query: 899 QLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVT 958 + +++ R+ + QK I D IE + I + + KK L ++ ++ Sbjct: 782 VKQGNQAHEDRVCAQEIVGRAQKLGYIGDNPIEASEYITNTV--KKQLGDELDRAKNDNN 839 Query: 959 QLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEIN-KLNAL 1017 +AQ++ ++ I+ L+ ++ K + + + K + E+ I E+ K + + Sbjct: 840 AKQAQIKGMQDKIDELSEKLDTATKTSDDKDKDYAAKMKA-----AEKQIKELQAKADDI 894 Query: 1018 LKQKDEEIIALNQKINNAQVSYMSM-VSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQ 1076 K+ +E + NQ + ++ VSD ++ L + +E + ++ +D Q Sbjct: 895 AKEFTDEAESKNQLEGKLKAIIGALGVSDPDTGLQAAQMSFQKAKEFDENLAIIKVDEDQ 954 Query: 1077 HNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXX 1136 + + L + + ++++ ++ P ++ ++ I+ + D+ N V+ Sbjct: 955 AVDTVANL-NNKGQVLSQIQDM-----ISTPNSDKVV--PAIKKLVDERNKVE----QFL 1002 Query: 1137 XXXXXLKVQEEEEFIQERSVLQEQSAKLNTE-LQECYTKIIQLETLNTELTGHDVVNQEQ 1195 + + E E + V+ E+ + E Q K + G + Q Sbjct: 1003 ETNGAVPLPEAVEDV----VMNEKKLQFELENAQNIIKKFYDANGMIMPQPGASPTKKSQ 1058 Query: 1196 I-NQLKSKLEQLNTENDNLLSTVAELR------SSISSAVD--QRGFEIAELWKQHLAQR 1246 I ++ + EQ D ++ + + SS+ AV+ + + E KQ Q+ Sbjct: 1059 IFKDIEKQREQAQENRDAIIDVLEQAHKLGYGASSLDEAVEAIKNAVQKDEKKKQDALQQ 1118 Query: 1247 EADFQKTEHELRVQLSAFESKYEQLLD--SVQSSTQEETNKIV--TMEQVTSLQNKLQDK 1302 + F + + L ++ +S+ +L D + Q + K + E+++ LQNK +++ Sbjct: 1119 Q--FSQEKDALLDEIEELQSQNAKLADENAQQQKLLNDQEKALADADEEISELQNKAENQ 1176 Query: 1303 EEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQM 1362 ++ + ++ + ++E +++E+++EK + Q + + Sbjct: 1177 SSNIASKNKENEAIAKKLEDIKAELQNEKKEHEADKAAADKKLKDLQQQKAQQEQDFAEE 1236 Query: 1363 Q---EQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLE--LKD--SE 1415 + E+ I N+ ++N KK + + AK E + + D + Sbjct: 1237 KADLEEQIQNLTKQNENAKKDNDALAGKLAATEEELKQTIAKDNEEIENAKKTINDLGKQ 1296 Query: 1416 IYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYET 1475 QK E T+T D+ E+++ L + ++ ++L ++A L+ + ++ YE Sbjct: 1297 AKQKDKEAASTVTDLEDKIEDLQNNLNQSQRDNDNL----NKKVAALQEEQNQKDQQYEA 1352 Query: 1476 ----MQKE-SEIERVKLIEE-----LNVKITESV-SLNKQVAELNKALEEEVAKTN-EMQ 1523 +Q + ++++ K +E LN + E + LNK++ E+ +A ++++ + N + + Sbjct: 1353 ELEKLQNQLKQLQQQKAQQEQDNNKLNDEKDEEIQQLNKEIEEMQRANDQKIREMNKQAK 1412 Query: 1524 TALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKE 1579 ++ +I+ LND+I L + + S+ QK + ++E+L N + K+ Sbjct: 1413 QKDDDNNNQIMNLNDQIEAL----KKNLSQAQKDNEGLNKKLAEKEEELSNVIAKD 1464 Score = 118 bits (283), Expect = 2e-24 Identities = 292/1463 (19%), Positives = 581/1463 (39%), Gaps = 141/1463 (9%) Query: 212 EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLE---------- 261 ++ +Q+M +M + E E E Q L IE +++ + N L Sbjct: 340 DENEQKMKEMNKQNKQKEQETNAEFQNLHDQIEQLQKQLAQSQRENDTLNKRINNLQGDK 399 Query: 262 -AARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIAN 320 E + E KL +L+Q +Q+ + + + +++E AN Sbjct: 400 ATQDKEYAEELEKLENQLKQLQQQKQQTEQELSKQKEQNAQDLQKAQEQMDEMQKQNDAN 459 Query: 321 MTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISR---KSGRN 377 + + + LE Q +Q K E K+ + + V + + + +S KS + Sbjct: 460 DKKNQAQAKALEEELEQAKQQLKNQEQKINDLNAQKTQVEQKAAQNNTDMSNALEKSKND 519 Query: 378 T-ASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXX 436 A+K ++ Q + D K+I+ E ++ + NK D + + Sbjct: 520 VEAAKRENDLLQKKLAQITSDLQKQIDALEEENGDLK-EEANKANADCAKAKEQLNKAIA 578 Query: 437 XXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDV 496 K+ +L + +G I N E N++AK +EQL+Q ++ K Sbjct: 579 DTKKQLADKEQTHEELLKNSNEEKQG---IKKKLN-ETANDLAKTKEQLQQMAEEKDKTQ 634 Query: 497 NVKDLIE-KLKSAEEQI---TQLNDEI-DAANKNMIKV-KSNHKLKLKQMQKTIDNFSKV 550 + D E K K+AE Q+ +Q N ++ D + M + +N+ LK +Q +N S Sbjct: 635 SKLDAEEGKRKNAENQLKLLSQQNSDLKDLIEQAMHAIGATNNDDLLKAIQ---NNASAQ 691 Query: 551 SDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEM-ENLA 609 S +K + L Q + + E+ ++ L + G I S V + ENL Sbjct: 692 STLDKACRNIGVSQAELPQTLTNIANERKHMMSTLQVPEKGGDIASKVDSLANQYKENLE 751 Query: 610 E-TRLKAISLLESQKFDL------VQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSV 662 E LKA + + F+ + ++Q ED++ + Q I Sbjct: 752 ELNNLKAYNKKFGKAFNFEFNPNETTLKNAVKQGNQAHEDRVCAQEIVGRAQKLGYIGDN 811 Query: 663 HLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLT- 721 +E + KK+L ++ K D IK +++ +++ KL + + D Sbjct: 812 PIEASEYITNTVKKQLGDELDRAKNDNNAKQAQIKGMQDKIDELSEKLDTATKTSDDKDK 871 Query: 722 DKLEKMSA--EKISELLAKINH-------EEQSKIQTQFGIDAKI-----QERDLYIENI 767 D KM A ++I EL AK + E +SK Q + + A I + D ++ Sbjct: 872 DYAAKMKAAEKQIKELQAKADDIAKEFTDEAESKNQLEGKLKAIIGALGVSDPDTGLQAA 931 Query: 768 ESELSKYKSRICRLEESIAVM---EDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELV 824 + K K +E++A++ ED+ + G L + Q S T D++V Sbjct: 932 QMSFQKAKE----FDENLAIIKVDEDQAVDTVANLNNKGQVLSQIQDMIS--TPNSDKVV 985 Query: 825 NRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKAN 884 + L+D VE Q LE + +++ E + LQ L + Q + AN Sbjct: 986 PAIKKLVDERNKVE-QFLETNGAVPLPEAVEDVVMNEKK-LQFELENAQNIIKKFYD-AN 1042 Query: 885 RTDLAE--SESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRD 942 + + + TK +D+E ++ E++ I+ ++ L ++ ++ A+ Sbjct: 1043 GMIMPQPGASPTKKSQIFKDIEKQREQ-AQENRDAIIDVLEQAHKLGYGASS-LDEAVEA 1100 Query: 943 KKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQ-----Q 997 K +K EK + +A Q++ + L +EEL N +L D++ Q+Q Q Sbjct: 1101 IKNAVQKDEKKKQ-----DALQQQFSQEKDALLDEIEELQSQNAKLADENAQQQKLLNDQ 1155 Query: 998 TQSPDYTEQYINEI-NKL-----NALLKQKDEEIIA-----LNQKINNAQVSYMS----- 1041 ++ ++ I+E+ NK N K K+ E IA + ++ N + + + Sbjct: 1156 EKALADADEEISELQNKAENQSSNIASKNKENEAIAKKLEDIKAELQNEKKEHEADKAAA 1215 Query: 1042 --MVSDYESKLAQ----FTTKLENMEEEMQRVSKQLLDSKQHN-----------EELQIL 1084 + D + + AQ F + ++EE++Q ++KQ ++K+ N EEL+ Sbjct: 1216 DKKLKDLQQQKAQQEQDFAEEKADLEEQIQNLTKQNENAKKDNDALAGKLAATEEELKQT 1275 Query: 1085 VREQDDQIKELKET--KLTFEMNIPKTEGMIISSTIEPMSDDA-NNVDXXXXXXXXXXXX 1141 + + +++I+ K+T L + E + +E +D NN++ Sbjct: 1276 IAKDNEEIENAKKTINDLGKQAKQKDKEAASTVTDLEDKIEDLQNNLNQSQRDNDNLNKK 1335 Query: 1142 LKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKS 1201 + +EE+ Q+ + + KL +L++ + Q E N +L E+I QL Sbjct: 1336 VAALQEEQN-QKDQQYEAELEKLQNQLKQLQQQKAQQEQDNNKLNDE---KDEEIQQLNK 1391 Query: 1202 KLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQRE--ADFQKTEHELRV 1259 ++E++ ND + E+ D +I L Q A ++ + QK L Sbjct: 1392 EIEEMQRANDQ---KIREMNKQAKQKDDDNNNQIMNLNDQIEALKKNLSQAQKDNEGLNK 1448 Query: 1260 QLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQ 1319 +L+ K E+L + + E N +Q+ L + + KE+ + E+ D Q Sbjct: 1449 KLA---EKEEELSNVIAKDNDEIEN---AKKQINDLNKQNKQKEKDSNSQIEELKD---Q 1499 Query: 1320 IEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKK 1379 I++L + + + + N Q+ Q +NE N Q K+ Sbjct: 1500 IDVLENTLAQVQRDLETTQKKLADKEAELAETIAKGNAEQDQLNNQ----LNELNKQGKQ 1555 Query: 1380 SSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQ 1439 ++ +A + + + + ++ K E T+ + NDE E R+ Sbjct: 1556 KDKENAAAMSQAKEQIEQLQAALNQAQKDNDNANKKLQAKDEELNQTIAKDNDELEKQRK 1615 Query: 1440 QLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESV 1499 Q + K+ + E ++ L+ ++ + + K++E K + E ++ ++V Sbjct: 1616 QYNDLNKQKQQKDKENADQIQNLQDQIAKLQKQGAQLLKDNE-NLGKKLNEKEEELKQTV 1674 Query: 1500 SLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVS 1559 + + + E K ++ K ++ Q EN +++ L ++I +LQ + A + + + + Sbjct: 1675 AKDTEEMEKQKKTISDLNKQSK-QKDRENGN-QVMDLQEQIEDLQKSL-AQAQRDNEVLG 1731 Query: 1560 FASDTKQGRDEQLDNTMNKELLD 1582 Q EQ +N +K+ ++ Sbjct: 1732 KKIGNLQNEQEQ-ENQEHKDAIE 1753 Score = 111 bits (268), Expect = 1e-22 Identities = 232/1139 (20%), Positives = 473/1139 (41%), Gaps = 99/1139 (8%) Query: 140 QLGDVTHLSNTIKEKDNALS-VLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXX 198 Q+ ++T + K+ ++AL+ L + ++ TI E+I + I K Sbjct: 1243 QIQNLTKQNENAKKDNDALAGKLAATEEELKQTIAKDNEEIENAKKTINDLGKQAKQKDK 1302 Query: 199 XXXXXXXXXXXXXEDTKQQMTKMQ---ENFIAMEAEWKDEKQRLLKDIESKDVRISSLEE 255 ED + + + Q +N A ++E+ + KD + + + L+ Sbjct: 1303 EAASTVTDLEDKIEDLQNNLNQSQRDNDNLNKKVAALQEEQNQ--KD-QQYEAELEKLQN 1359 Query: 256 ANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGS 315 K L+ + + +++KL E ++ Q I ++ + ++ + Sbjct: 1360 QLKQLQQQKAQQEQDNNKLNDEKDEEIQQLNKEIEEMQRANDQKIREMNKQAKQKDDDNN 1419 Query: 316 LEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTE-SKAVSSPSKKGSPLISRKS 374 +I N+ + +IE L+ Q ++ N+ L KLA E S ++ + + + + Sbjct: 1420 NQIMNLND---QIEALKKNLSQAQKDNEGLNKKLAEKEEELSNVIAKDNDEIENAKKQIN 1476 Query: 375 GRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTX 434 N +K K S E L D + +N +A+++ +++ K L DKE ++E Sbjct: 1477 DLNKQNKQKEKDSNSQIEELKDQID--VLENTLAQVQRDLETTQKKLADKEAELAE---- 1530 Query: 435 XXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIK 494 +D L QL ++Q + N +++ + EQL+ LN K Sbjct: 1531 --TIAKGNAEQDQLNNQLNELNKQGKQKDK-----ENAAAMSQAKEQIEQLQAALNQAQK 1583 Query: 495 DVNVKDLIEKLKSAEEQITQL----NDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFS-K 549 D + + +KL++ +E++ Q NDE++ K + + K K+ I N + Sbjct: 1584 DNDNAN--KKLQAKDEELNQTIAKDNDELEKQRKQYNDLNKQKQQKDKENADQIQNLQDQ 1641 Query: 550 VSDSNKEIVRLTEELHHLSQKVAELEEE-KGNLQLHLVDYDSGRMIESDVYKKMIEMENL 608 ++ K+ +L ++ +L +K+ E EEE K + + + + SD+ K+ + + Sbjct: 1642 IAKLQKQGAQLLKDNENLGKKLNEKEEELKQTVAKDTEEMEKQKKTISDLNKQSKQKDR- 1700 Query: 609 AETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSV--HLEE 666 E + + L E Q DL + L Q+ + + K+ ++ Q + +Q E K +LE Sbjct: 1701 -ENGNQVMDLQE-QIEDLQKSLAQAQRDNEVLGKKIGNL-QNEQEQENQEHKDAIENLEN 1757 Query: 667 QIDALSASKKELALVIENLKLDK----EQLYGTIKDLENDKEDIMNKLQNYIQE-NMD-- 719 QI AL+ K ++ K + EQL I+DL+ E K Q + N D Sbjct: 1758 QIKALNQQKNQVEQEKNKQKEQQDDEIEQLKQQIEDLQKQAEINDKKHQQQVASLNGDVA 1817 Query: 720 -LTDKLEKMSAEKI-SELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSR 777 L +KLE M+ +K +E A E+ K+ + +A QE+D + + + R Sbjct: 1818 GLQEKLEAMTQQKNDAEHKAAQTKEDLDKVNQEN--EANKQEKDQLQKKLNQTAGDLQKR 1875 Query: 778 ICRLEESIAVMEDRRYS----LERKADQLGSYLQEKQKAYSEYT-IQEDELVN------- 825 + L+E + + L+R + L+EK++ + + I DEL + Sbjct: 1876 VKELQEENETLHEEAVKNNEQLQRALSDVKKQLKEKEREHDNLSRISGDELNDLKRENEG 1935 Query: 826 ---RLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEK 882 +LA + + + E+QL + +E K+L++K Q L ++ +++ L+ ++ + ++ Sbjct: 1936 LKEQLAKVTEDKKEAERQLAQTNNEKKDLEEKFQKLADDKKDVDDKLAKTEKELAKVNDE 1995 Query: 883 ANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDL-EIEFN-TQIESAI 940 + E K + DL+ L R+ + Q ++ + + L E E N Q +S + Sbjct: 1996 KKEAEGKLEELGKKDKLVSDLDGQLARVKSQAQAAQDEQAQTRDKLKETEANLAQAQSQV 2055 Query: 941 RDKKVLNEKY-----EKNIEYVTQLEAQLQEYKNNIENL--NMNVEELNKMNLELID--K 991 + ++ +K K ++ + Q + L+ ++++ + M +E+L D Sbjct: 2056 NNLQIFIDKLCAALSCKQVQAI-QTASNLKLLRDSLVKVFGEMTIEDLIVAFNSYNDSRN 2114 Query: 992 HVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLA 1051 VQ + T D+ + I+ I N + + Q++ + + S LA Sbjct: 2115 QVQVELTSLRDFVAKIISTIT--NGAARVTFPMATEIQQRV--------IQIVEKSSILA 2164 Query: 1052 QFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEG 1111 + K ++ E +QR NE + + + + +I + +E L I +T Sbjct: 2165 RNDRK--SVSEVLQRAGTVGYQGNDLNEAVDV-IADYAARI-QAQEKLLEIREEIDQTRK 2220 Query: 1112 MIISSTIEPMSDDA---NNVDXXXXXXXXXXXXLKVQEEEEFIQERSV---LQEQSAKLN 1165 M+ D+A ++ + +EEE Q +S+ ++E KL Sbjct: 2221 MLEKEVESRSQDNAASKKKLEEAHQRYAEAKAAARQKEEENASQIQSLEANIRELEDKLR 2280 Query: 1166 TE--LQECYTKIIQLETLNTELTGHDVVNQEQIN-QLKSKLEQLNTENDNLLSTVAELR 1221 E L+E T+I Q +T + L + +QE +L + L E+ L++ + + R Sbjct: 2281 VEKQLREEITRIGQGKTADMRLIKAKLSDQEFATIELINNLMAKERESSRLMANLRKAR 2339 Score = 111 bits (267), Expect = 2e-22 Identities = 274/1482 (18%), Positives = 585/1482 (39%), Gaps = 136/1482 (9%) Query: 174 DLQEKI-NEKDQI--IEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEA 230 DL+ ++ N D+I +E +NK T ED +++TK E Sbjct: 256 DLENQLKNANDEIETLEQRNKDLTAQKQNNDNKNASRINELEDEVEKLTKDCETLKIKNG 315 Query: 231 EWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXX 290 K + Q +D +KD + L + N E E++ ++ + QE Sbjct: 316 SLKKKLQAASQDNMNKDEAMKQLRDEN---EQKMKEMNKQNKQKEQE---TNAEFQNLHD 369 Query: 291 XXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLA 350 L KQ + E T + +L+ T+ + E LE L Q++Q ++ + Sbjct: 370 QIEQLQKQLAQSQRENDTLNKRINNLQGDKATQDKEYAEELEKLENQLKQLQQQKQQTEQ 429 Query: 351 TMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKL 410 + + + + +K + +N A+ K +Q ++ L ++ ++ K ++ Sbjct: 430 ELSKQKEQNAQDLQKAQEQMDEMQKQNDANDKK---NQAQAKALEEELEQA--KQQLKNQ 484 Query: 411 EMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXG--------KDTL---IAQLQLEHQQH 459 E I LN E ++ +T D L +AQ+ + Q+ Sbjct: 485 EQKINDLNAQKTQVEQKAAQNNTDMSNALEKSKNDVEAAKRENDLLQKKLAQITSDLQKQ 544 Query: 460 MEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEI 519 ++ + G E+ N+ + K++LN I D K L +K ++ EE + N+E Sbjct: 545 IDALEEEN-GDLKEEANKANADCAKAKEQLNKAIADTK-KQLADKEQTHEELLKNSNEEK 602 Query: 520 DAANKNMIKVKSN---HKLKLKQMQKTIDNF-SKVSDSNKEIVRLTEELHHLSQKVAELE 575 K + + ++ K +L+QM + D SK+ + +L LSQ+ ++L Sbjct: 603 QGIKKKLNETANDLAKTKEQLQQMAEEKDKTQSKLDAEEGKRKNAENQLKLLSQQNSDL- 661 Query: 576 EEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQEL-HILQ 634 ++ +H + G D+ K + + T KA + + +L Q L +I Sbjct: 662 KDLIEQAMHAI----GATNNDDLLKAIQNNASAQSTLDKACRNIGVSQAELPQTLTNIAN 717 Query: 635 QKYD-----EVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIE-NLKLD 688 ++ +V +K DI+ + D + ++ K +LEE ++ L A K+ + Sbjct: 718 ERKHMMSTLQVPEKGGDIAS-KVDSLANQYKE-NLEE-LNNLKAYNKKFGKAFNFEFNPN 774 Query: 689 KEQLYGTIKDLENDKED------IMNKLQ--NYIQEN-MDLTDKLEKMSAEKISELLAKI 739 + L +K ED I+ + Q YI +N ++ ++ + +++ + L + Sbjct: 775 ETTLKNAVKQGNQAHEDRVCAQEIVGRAQKLGYIGDNPIEASEYITNTVKKQLGDELDRA 834 Query: 740 ---NHEEQSKIQ-TQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSL 795 N+ +Q++I+ Q ID ++ D + + + Y +++ E+ I ++ + + Sbjct: 835 KNDNNAKQAQIKGMQDKIDELSEKLDTATKTSDDKDKDYAAKMKAAEKQIKELQAKADDI 894 Query: 796 ERK-ADQLGS--YLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVE----KQLLEIEHEN 848 ++ D+ S L+ K KA D A M + E +++++ + Sbjct: 895 AKEFTDEAESKNQLEGKLKAIIGALGVSDPDTGLQAAQMSFQKAKEFDENLAIIKVDEDQ 954 Query: 849 -----KELQKKNQILLEENQNLQISLSD-MQQHYNALVEKANRTD--LAESESTKYQTQL 900 L K Q+L + + SD + LV++ N+ + L + + + Sbjct: 955 AVDTVANLNNKGQVLSQIQDMISTPNSDKVVPAIKKLVDERNKVEQFLETNGAVPLPEAV 1014 Query: 901 RDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQL 960 D+ N K++ E + K+ D Q ++ K + + EK E + Sbjct: 1015 EDVVMNEKKLQFELEN-AQNIIKKFYDANGMIMPQPGASPTKKSQIFKDIEKQREQAQEN 1073 Query: 961 EAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQ 1020 + + L L++ +E I VQK + + D +Q ++ + +ALL Sbjct: 1074 RDAIIDVLEQAHKLGYGASSLDEA-VEAIKNAVQKDEKKKQDALQQQFSQ--EKDALL-D 1129 Query: 1021 KDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNE- 1079 + EE+ + N K+ + +++D E LA ++ ++ + + S + + NE Sbjct: 1130 EIEELQSQNAKLADENAQQQKLLNDQEKALADADEEISELQNKAENQSSNIASKNKENEA 1189 Query: 1080 ----------ELQILVREQ-------DDQIKELKETKLTFEMNIPKTEGMIISSTIEPMS 1122 ELQ +E D ++K+L++ K E + + E + I+ ++ Sbjct: 1190 IAKKLEDIKAELQNEKKEHEADKAAADKKLKDLQQQKAQQEQDFAE-EKADLEEQIQNLT 1248 Query: 1123 DDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLN 1182 N + + ++ ++ ++ +N ++ K + + Sbjct: 1249 KQNENAKKDNDALAGKLAATEEELKQTIAKDNEEIENAKKTINDLGKQAKQKDKEAASTV 1308 Query: 1183 TELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQ- 1241 T+L +++I L++ L Q +NDNL VA L+ + Q E+ +L Q Sbjct: 1309 TDL-------EDKIEDLQNNLNQSQRDNDNLNKKVAALQEEQNQKDQQYEAELEKLQNQL 1361 Query: 1242 -HLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQ 1300 L Q++A ++ ++L + + + +QL ++ + KI M + + K Sbjct: 1362 KQLQQQKAQQEQDNNKLNDEK---DEEIQQLNKEIEEMQRANDQKIREMNK--QAKQKDD 1416 Query: 1301 DKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYK 1360 D + NL + QIE L+ + + + +N + Sbjct: 1417 DNNNQIMNLND-------QIEALKKNLSQAQKDNEGLNKKLAEKEEELSNVIAKDNDEIE 1469 Query: 1361 QMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKT 1420 ++Q I ++N++N Q +K S +++ E + ++ LE ++ K Sbjct: 1470 NAKKQ-INDLNKQNKQKEKDS---NSQIEELKDQIDVLENTLAQVQRDLETTQKKLADKE 1525 Query: 1421 HEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKES 1480 E T+ + N E + + QL E K+ + +K+ E A + E + ++ Sbjct: 1526 AELAETIAKGNAEQDQLNNQLNELNKQGK----QKDKENAAAMSQAKEQIEQLQAALNQA 1581 Query: 1481 EIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEI 1540 + + ++L K E LN+ +A+ N LE++ + N++ + ++ E D+I Sbjct: 1582 QKDNDNANKKLQAKDEE---LNQTIAKDNDELEKQRKQYNDLNKQKQQKDKENA---DQI 1635 Query: 1541 TNLQNMV---RASSSKIQKHVSFASDTKQGRDEQLDNTMNKE 1579 NLQ+ + + +++ K ++E+L T+ K+ Sbjct: 1636 QNLQDQIAKLQKQGAQLLKDNENLGKKLNEKEEELKQTVAKD 1677 Score = 99.1 bits (236), Expect = 9e-19 Identities = 149/754 (19%), Positives = 313/754 (41%), Gaps = 68/754 (9%) Query: 838 EKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQ 897 E+Q+ E+E E EL+K IL ++ L+ ++H N+ E A + E + Sbjct: 6 ERQINEMEAEIDELKKDIDILKTKHDALK------KKHKNSNDEHAEQLSQLRLEKDDLE 59 Query: 898 TQLRDLESNLKRITHEHQT--------LIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEK 949 +L+++ + K+I + T ++Q + ++++L + + + L + Sbjct: 60 KKLKEI-TQQKQIAEQQATSQIASLNDQVMQLQGKLDNLSKQLEASQKKLSQTTSELGGE 118 Query: 950 YEKNIEYVTQLEAQLQEYKN----NIENLNMNVEEL-NKMN--LELIDKHVQKQQTQSPD 1002 E+ E LE ++++ +N N + LN +++ K+N ++ +D Q+ + + Sbjct: 119 LEQTKENNANLEQKMKDLQNQNAKNAQALNDEKDQIQGKLNETMKELDNVKQQNDSLNKK 178 Query: 1003 Y---TEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLEN 1059 Y E NE+ AL Q ++++ N + A+ + + YE + AQ +LEN Sbjct: 179 YDTDVENLKNELEATKALNGQNEQKLKDANAQKTAAEQKLVQLQQQYEDQTAQLKQELEN 238 Query: 1060 MEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIE 1119 + + +K+ ++L+ ++ +D+I+ L++ + +S I Sbjct: 239 NKRDNDTNAKK---QATLQKDLENQLKNANDEIETLEQRNKDLTAQKQNNDNK-NASRIN 294 Query: 1120 PMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLE 1179 + D+ + LK ++ + Q+ E +L E ++ ++ + Sbjct: 295 ELEDEVEKLTKDCETLKIKNGSLK-KKLQAASQDNMNKDEAMKQLRDENEQKMKEMNKQN 353 Query: 1180 TLNTELTGHDVVN-QEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAEL 1238 + T + N +QI QL+ +L Q END L + L+ + D+ E E Sbjct: 354 KQKEQETNAEFQNLHDQIEQLQKQLAQSQRENDTLNKRINNLQGD-KATQDKEYAEELEK 412 Query: 1239 WKQHLAQREADFQKTEHEL---RVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSL 1295 + L Q + Q+TE EL + Q + K ++ +D +Q Q + N Q +L Sbjct: 413 LENQLKQLQQQKQQTEQELSKQKEQNAQDLQKAQEQMDEMQK--QNDANDKKNQAQAKAL 470 Query: 1296 QNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTE 1355 + +L+ ++ L+N ++K IN + ++++E + + E Sbjct: 471 EEELEQAKQQLKNQEQK----INDLNAQKTQVEQKAAQNNTDMSNALEKSKNDVEAAKRE 526 Query: 1356 N--------QSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTH 1407 N Q +Q+Q I + EEN LK+ + ++N A A Sbjct: 527 NDLLQKKLAQITSDLQKQ-IDALEEENGDLKEEANKANADCAKAKEQLNKAIADT----- 580 Query: 1408 QLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMH 1467 + +L D E +THE L N+E + ++++L E + T E+ ++A + K Sbjct: 581 KKQLADKE---QTHEE--LLKNSNEEKQGIKKKLNETANDLAK-TKEQLQQMAEEKDKTQ 634 Query: 1468 ENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVA------ELNKALEEEVAKTNE 1521 + E +K +E ++KL+ + N + + + +L KA++ + + Sbjct: 635 SKLDAEEGKRKNAE-NQLKLLSQQNSDLKDLIEQAMHAIGATNNDDLLKAIQNNASAQST 693 Query: 1522 MQTALENQEIEIVTLNDEITNLQNMVRASSSKIQ 1555 + A N + L +TN+ N + S +Q Sbjct: 694 LDKACRNIGVSQAELPQTLTNIANERKHMMSTLQ 727 Score = 95.5 bits (227), Expect = 1e-17 Identities = 136/754 (18%), Positives = 321/754 (42%), Gaps = 62/754 (8%) Query: 639 EVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKD 698 ++ + A+I +L+ D + K L+++ S E A + L+L+K+ L +K+ Sbjct: 8 QINEMEAEIDELKKDIDILKTKHDALKKKH---KNSNDEHAEQLSQLRLEKDDLEKKLKE 64 Query: 699 LENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQ 758 + K+ + + I L D++ ++ K+ L ++ ++ QT + +++ Sbjct: 65 ITQQKQIAEQQATSQIAS---LNDQVMQLQG-KLDNLSKQLEASQKKLSQTTSELGGELE 120 Query: 759 ERDLYIENIESELSKYKSRICRLEESIAVMEDR-RYSLERKADQLGSYLQEKQKAYSEYT 817 + N+E ++ +++ + +++ +D+ + L +L + Q+ +Y Sbjct: 121 QTKENNANLEQKMKDLQNQNAKNAQALNDEKDQIQGKLNETMKELDNVKQQNDSLNKKYD 180 Query: 818 IQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYN 877 + L N L + E++L + + ++K L++ Q + + ++Q Sbjct: 181 TDVENLKNELEATKALNGQNEQKLKDANAQKTAAEQK---LVQLQQQYEDQTAQLKQEL- 236 Query: 878 ALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIE 937 + N+ D ++ + K T +DLE+ LK E +TL Q+ K++ + + + Sbjct: 237 ----ENNKRD-NDTNAKKQATLQKDLENQLKNANDEIETL-EQRNKDLTAQKQNNDNKNA 290 Query: 938 SAIRDKKVLNEKYEKNIEYVT--------QLEAQLQEYKNNIENLNMNVEELNKMNLELI 989 S I + + EK K+ E + +L+A Q+ N E + +E + E+ Sbjct: 291 SRINELEDEVEKLTKDCETLKIKNGSLKKKLQAASQDNMNKDEAMKQLRDENEQKMKEMN 350 Query: 990 DKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESK 1049 ++ QK+Q + ++ + ++I +L L Q E LN++INN Q + +Y + Sbjct: 351 KQNKQKEQETNAEFQNLH-DQIEQLQKQLAQSQRENDTLNKRINNLQGDKATQDKEYAEE 409 Query: 1050 LAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKT 1109 L + +L+ ++++ Q+ ++L SKQ + Q L + Q+ + K+ + N + Sbjct: 410 LEKLENQLKQLQQQKQQTEQEL--SKQKEQNAQDLQKAQEQMDEMQKQNDANDKKN--QA 465 Query: 1110 EGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQ 1169 + + +E N + Q+ + +++ +++++A+ NT++ Sbjct: 466 QAKALEEELEQAKQQLKNQE---------------QKINDLNAQKTQVEQKAAQNNTDMS 510 Query: 1170 ECYTKIIQLETLNTELTGHDVVNQE--QI-NQLKSKLEQLNTENDNLLSTVAELRSSISS 1226 K + +D++ ++ QI + L+ +++ L EN +L + + + Sbjct: 511 NALEK--SKNDVEAAKRENDLLQKKLAQITSDLQKQIDALEEENGDLKEEANKANADCAK 568 Query: 1227 AVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKI 1286 A +Q IA+ KQ LA +E ++ + + K + + + + T+E+ ++ Sbjct: 569 AKEQLNKAIADTKKQ-LADKEQTHEELLKNSNEEKQGIKKKLNETANDL-AKTKEQLQQM 626 Query: 1287 VTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXX 1346 E+ Q+KL +E +N + NQ+++L + D K Sbjct: 627 A--EEKDKTQSKLDAEEGKRKNAE-------NQLKLLSQQNSDLKDLIEQAMHAIGATNN 677 Query: 1347 XXXXDLRTENQSYKQMQEQSILNINEENAQLKKS 1380 N S + +++ NI A+L ++ Sbjct: 678 DDLLKAIQNNASAQSTLDKACRNIGVSQAELPQT 711 Score = 67.3 bits (157), Expect = 3e-09 Identities = 102/573 (17%), Positives = 242/573 (42%), Gaps = 44/573 (7%) Query: 1043 VSDYESKLAQFTTKLENMEEEMQRVSKQLLDSK-QHNEELQILVREQDDQIKELKETKLT 1101 +++ E+++ + ++ ++ + + K+ +S +H E+L L E+DD K+LKE +T Sbjct: 9 INEMEAEIDELKKDIDILKTKHDALKKKHKNSNDEHAEQLSQLRLEKDDLEKKLKE--IT 66 Query: 1102 FEMNIPKTEGMI-ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQ 1160 + I + + I+S + + +D L Q E E +E Sbjct: 67 QQKQIAEQQATSQIASLNDQVMQLQGKLDNLSKQLEASQKKLS-QTTSELGGELEQTKEN 125 Query: 1161 SAKLNTELQECYTKIIQ-LETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLL----S 1215 +A L ++++ + + + LN E D + Q ++N+ +L+ + +ND+L + Sbjct: 126 NANLEQKMKDLQNQNAKNAQALNDE---KDQI-QGKLNETMKELDNVKQQNDSLNKKYDT 181 Query: 1216 TVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSV 1275 V L++ + + G +L K AQ+ A QK +L+ Q ++ +Q L++ Sbjct: 182 DVENLKNELEATKALNGQNEQKL-KDANAQKTAAEQKLV-QLQQQYEDQTAQLKQELENN 239 Query: 1276 QSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADV--------------INQIE 1321 + K T+++ L+N+L++ + + L+++ D+ IN++E Sbjct: 240 KRDNDTNAKKQATLQK--DLENQLKNANDEIETLEQRNKDLTAQKQNNDNKNASRINELE 297 Query: 1322 ILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSS 1381 ++ + D ++++ KQ+++++ + E N Q K+ Sbjct: 298 DEVEKLTKDCETLKIKNGSLKKKLQAASQDNMNKDEAMKQLRDENEQKMKEMNKQNKQKE 357 Query: 1382 XXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQ-------KTHEYTITLTQRNDEF 1434 ++ + ++ + + + + I + EY L + ++ Sbjct: 358 QETNAEFQNLHDQIEQLQKQLAQSQRENDTLNKRINNLQGDKATQDKEYAEELEKLENQL 417 Query: 1435 ENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVK 1494 + ++QQ + E+ + + +L + +M E + K+++ + L EEL Sbjct: 418 KQLQQQKQQTEQELSKQKEQNAQDLQKAQEQMDEMQKQNDANDKKNQAQAKALEEELEQA 477 Query: 1495 ITESVSLNKQVAELN---KALEEEVAKTN-EMQTALENQEIEIVTLNDEITNLQNMVRAS 1550 + + +++ +LN +E++ A+ N +M ALE + ++ E LQ + Sbjct: 478 KQQLKNQEQKINDLNAQKTQVEQKAAQNNTDMSNALEKSKNDVEAAKRENDLLQKKLAQI 537 Query: 1551 SSKIQKHVSFASDTKQGRDEQLDNTMNKELLDA 1583 +S +QK + A + + G ++ N N + A Sbjct: 538 TSDLQKQID-ALEEENGDLKEEANKANADCAKA 569 >UniRef50_A0CFL4 Cluster: Chromosome undetermined scaffold_176, whole genome shotgun sequence; n=1; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_176, whole genome shotgun sequence - Paramecium tetraurelia Length = 1842 Score = 134 bits (324), Expect = 2e-29 Identities = 284/1412 (20%), Positives = 594/1412 (42%), Gaps = 115/1412 (8%) Query: 169 ETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAM 228 E +L I Q E +N T ++T++ + Q N + Sbjct: 283 EMVVLQKDSDIQALQQTTEVQNVQLTQSQSFNNDLQLSYQQETQNTEKDYNQNQINTLKQ 342 Query: 229 EAE--WKDEKQRLLKDIESKDVRISSLEEAN---KLLEAARFEISLEHSKLAQELEQXXX 283 + D K+ LK ++ K V+ S++ + N +LLE ++ L ++KL E++Q Sbjct: 343 QIAKLTSDLKECELKHVQVKQVQESTISKLNHDVRLLEQKNEDLILHNNKLINEIKQNEL 402 Query: 284 XXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNK 343 + Q I E +E +E N E K+ ++E LN Q+ Q +K Sbjct: 403 IQQKEST----IICQKISEF--EIQLLESHHQIEDLNQ-EKQKQERVVEKLNLQM-QASK 454 Query: 344 ELENKLATMGTE-SKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKI 402 ++++KL T+ + S K+ + S +S ++ S ++ + + LN D Sbjct: 455 QIQSKLEEDITKYQNFLISHHKQLEAVTSNESSDSSDSSEETITEK--PQQLNFDALCTK 512 Query: 403 NKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQL-QLEHQQHME 461 +I +++ ++ K + + + K + + +L QL+ + + Sbjct: 513 LTEQIRLVQLRLEIYEKQIKQYKQELHSKTVEIQKLFSENSDSNLKVQRLSQLQPKFDNQ 572 Query: 462 GPSLIHVGTNTEDVNE-IAKVQEQLKQELND-EIKDVNVKDLIEKLKSAEEQITQLNDEI 519 + E++++ I K Q QL + N + ++ + L K QI Q++ I Sbjct: 573 EAIIKQKDLTIENLSQQITKQQAQLHENENKLQQLQIDKETLNRKNVELSNQI-QIHHTI 631 Query: 520 DAANKNMIKVKSNHK-----LKLKQMQKTIDNF--SKVSDSNKEIVRLTEELHHLSQKVA 572 KN +++ SN + ++L ++T + S+ N +I+ TEE + +Q + Sbjct: 632 ----KNDLQISSNKEDPIQHIELMSSEQTSTSIFDQTFSNINYQILLFTEE--NTTQIKS 685 Query: 573 ELEEEKGNLQLHLV-DYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELH 631 L + NL+ +L+ + + ++ + K ++NL E + + + + + + + Sbjct: 686 ILSNKIDNLENNLLRTINKYQKLQEIIQKNYHNIQNLYEQSQQNL-IQKENLYQIENQKQ 744 Query: 632 ILQQK--YDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDK 689 +Q++ +EV + ISQL++ Q ++ +L +Q +L + E K+D Sbjct: 745 QMQRQTLLEEVHQQTILISQLENQQQILSLQLKNLNQQNQDQKQVITQLQQLDEKQKIDD 804 Query: 690 EQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKIN--HEEQSKI 747 Q+ LE ++ +N+ + +++ + +LE + +++ +K+N +E + ++ Sbjct: 805 LQMGSNQTKLEELQQRTINQEAD-LKKASEQNTQLEIQVKDLNNQVQSKLNTINELRQEL 863 Query: 748 QTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQ 807 + Q + ++ + ++ + S L + +D + L R+ + L LQ Sbjct: 864 DSLKNNQTGSQFDSIKLQQQQKQILELISNNTNLNQQ---SQDAQLRL-REMEALNLELQ 919 Query: 808 EKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQI 867 ++ S+ + + E +N+L +++ KQ L + LQK+ L EN+ LQ Sbjct: 920 DRVNQLSKQGVSQKETINQL---QQQNQMEVKQNLTFLQQMDPLQKQIDHLTRENRKLQQ 976 Query: 868 SLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIED 927 S +D ++ Y L + + + Q Q++ LE + +I ++ Q I +K E+ + Sbjct: 977 SNNDFEKAYGKLPTYGSPRKVQNQD----QNQIKKLEDEILQIQYKFQQEIQEKNIELNN 1032 Query: 928 LEIEFNTQIESAIRDKKVLN-EKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNL 986 ++ ++ Q+E +R+ K+ K E+N ++ Q Q N + N +E N Sbjct: 1033 IQKQYEQQLEE-VRELKLDEISKLEQNCVILSNQLKQQQVVNNELLQNNSQIERDNSQLS 1091 Query: 987 ELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDY 1046 E I+K ++Q+ QS + ++ + + +++N K I LNQ I N Q+ +++D Sbjct: 1092 EEIEKLKKQQKLQSQN--QESLKQQDQINHECK-----YIELNQTIGNLQI----IINDQ 1140 Query: 1047 ESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNI 1106 +L F ++EE+++ Q+ + + EEL QIK+ ++ TF N Sbjct: 1141 NLQLLNFKNHTLDLEEQIKHFEVQIQNLIKEKEEL--------CQIKDSNKSDETFTKNQ 1192 Query: 1107 PKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNT 1166 E + +E + ++ +D +V +++ +Q++ + Q Q Sbjct: 1193 QNEELDSQNQLMEQLKNEQFILD-------------QVNQDKLKLQQQQIEQGQLIHQQQ 1239 Query: 1167 ELQEC-YTKIIQLETLNTELTGHDVVNQEQINQLKS-KLEQLNTENDNLLSTVAELRSSI 1224 ++ EC +I +L + + + + I++L+S + EQL EL+ Sbjct: 1240 QVIECQQVEIKRLTLIESGSVEQKKESDQNISKLQSNQAEQLLPVQQEEFQ--VELKQK- 1296 Query: 1225 SSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETN 1284 ++ + EI EL KQ L Q + E +L+ A E + +Q+ Q + Sbjct: 1297 QKQIEAKDIEIHEL-KQKLYQNLQLNNELEQQLK-DKQAISIALENEIKQLQNVNQTQLQ 1354 Query: 1285 KIVTMEQVTSLQ-NKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXX 1343 KI + Q +++++++ L N E+ A + ++ ++ + K+ Sbjct: 1355 KITELNQDFQRSFEQVEEQKQTLTNQSEQNALLESKCNQMQQNV--MKIQTQNNSLIQIN 1412 Query: 1344 XXXXXXXDLRTE-NQSYKQMQEQSI-LNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAK 1401 + + N Q QEQS + +++ N QL+ + E K Sbjct: 1413 QQLESTLEQQQHVNAQIIQKQEQSFQIQLDKLNIQLEDQQNQLKLLQQENGEYKQEIE-K 1471 Query: 1402 VLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAI 1461 ++ Q E K +E L Q E + Q+L++ R E L E ++E+ Sbjct: 1472 IMNDQKQWE------QNKLNE----LVQVKKESQGQIQKLMDQISRAEGLNVEHQNEI-- 1519 Query: 1462 LRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNE 1521 L+M +N +K+ I +IE+L +KI + ++ NKAL EE A E Sbjct: 1520 --LEM-DNVIKKLIQEKDKNINN-DMIEQLQIKIKMNEEQIGRLLMTNKALMEENAHLQE 1575 Query: 1522 -MQTALENQEIEIVTLNDEITNLQNMVRASSS 1552 ++ L + + N N +N V S+ Sbjct: 1576 QIKDDLNSSFCSNASQNCATKNQENEVSLPSN 1607 Score = 120 bits (288), Expect = 4e-25 Identities = 275/1457 (18%), Positives = 617/1457 (42%), Gaps = 128/1457 (8%) Query: 156 NALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTK 215 N ++L+ K I LQ+ I ++ IEA N+ ED + Sbjct: 5 NNEALLKQVNKNQTLLIQKLQDDIELLNEEIEASNQQIDTLKSQHHISLSQQQSIIEDLR 64 Query: 216 QQMTKMQENFIAMEAEWKDE--KQRLLK---DIESKDVR--ISSLEEANKLLEAARFEIS 268 + Q+ + +++++ + +LL+ D ++K + I L++ KL + Sbjct: 65 SECQNYQQQNMELQSKFTQSVLQNQLLQSKYDKKNKQYKDQIVELKQQIKLSHLKNQDYQ 124 Query: 269 LEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCE-EKTEIEEKGSLE-IANMTE-LT 325 + +L + L+ L +Q+ + + +++ + +E N+ + Sbjct: 125 RDILELRKSLDNNKLEICKLIDNSTLLNEQNKQLKANLDLQQVDYENKIEQYQNLIQDKD 184 Query: 326 KKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSP 385 ++I L+ + N + + +++E + + + K+ L+ + S + + Sbjct: 185 EEITLIINENGVLNRNLEQMEKSANLSESLHSQIDTLQKQNQNLLIQLSDLQNHNTLLRQ 244 Query: 386 WSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGK 445 QL S + + + + A + ++N++ V +E V+ +KD+ + Sbjct: 245 QLQLQSSEIQVSSSSLQLQLQSAPQQQTQDAMNRN-VQQEMVVLQKDSDIQALQQTTEVQ 303 Query: 446 DTLIAQ-------LQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELND-EIKDVN 497 + + Q LQL +QQ + + N +N + + +L +L + E+K V Sbjct: 304 NVQLTQSQSFNNDLQLSYQQETQNTEKDY---NQNQINTLKQQIAKLTSDLKECELKHVQ 360 Query: 498 VKDL----IEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDS 553 VK + I KL + Q N+++ N +I ++L ++Q + TI K+S+ Sbjct: 361 VKQVQESTISKLNHDVRLLEQKNEDLILHNNKLINEIKQNEL-IQQKESTII-CQKISEF 418 Query: 554 NKEIVRLTEELHHLSQKVAELEE--EKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAET 611 +++ ++ L+Q+ + E EK NLQ+ + + I+S + + + + +N + Sbjct: 419 EIQLLESHHQIEDLNQEKQKQERVVEKLNLQMQ-----ASKQIQSKLEEDITKYQNFLIS 473 Query: 612 RLKAISLLESQKFDLVQELHILQQKYDEVEDKLADI-SQLQSDQVCSEI-KSVHLEE-QI 668 K + + S + D E+ + + QL D +C+++ + + L + ++ Sbjct: 474 HHKQLEAVTSNESS---------DSSDSSEETITEKPQQLNFDALCTKLTEQIRLVQLRL 524 Query: 669 DALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMS 728 + K+ + + ++ ++L+ D N K +++LQ +N + K + ++ Sbjct: 525 EIYEKQIKQYKQELHSKTVEIQKLFSENSD-SNLKVQRLSQLQPKF-DNQEAIIKQKDLT 582 Query: 729 AEKISELLAKIN---HEEQSKIQTQFGIDAKIQERDLYIENIE-SELSKYKSRICRLEES 784 E +S+ + K HE ++K+Q Q ID + R +N+E S + I + Sbjct: 583 IENLSQQITKQQAQLHENENKLQ-QLQIDKETLNR----KNVELSNQIQIHHTIKNDLQI 637 Query: 785 IAVMEDRRYSLE-RKADQLGSYLQEKQKAYSEYTI---QEDELVNRLAVLMDHDRVVEKQ 840 + ED +E ++Q + + ++ + Y I E+ ++L + +E Sbjct: 638 SSNKEDPIQHIELMSSEQTSTSIFDQTFSNINYQILLFTEENTTQIKSILSNKIDNLENN 697 Query: 841 LLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQL 900 LL ++ ++LQ +I+ + N+Q QQ+ L++K N L + E+ K Q Q Sbjct: 698 LLRTINKYQKLQ---EIIQKNYHNIQNLYEQSQQN---LIQKEN---LYQIENQKQQMQR 748 Query: 901 RDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQL 960 + L L+ + H+ LI Q + + + L ++ K LN++ + + +TQL Sbjct: 749 QTL---LEEV-HQQTILISQLENQQQILSLQL-----------KNLNQQNQDQKQVITQL 793 Query: 961 EAQLQEYKNNIENLNMN-----VEELNK--MNLELIDKHVQKQQTQSPDYTEQYINEI-N 1012 + QL E K I++L M +EEL + +N E K +Q TQ + N++ + Sbjct: 794 Q-QLDE-KQKIDDLQMGSNQTKLEELQQRTINQEADLKKASEQNTQLEIQVKDLNNQVQS 851 Query: 1013 KLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLL 1072 KLN + + + +E+ +L +Q + + + ++ + + N+ ++ Q +L Sbjct: 852 KLNTINELR-QELDSLKNNQTGSQFDSIKL-QQQQKQILELISNNTNLNQQSQDAQLRLR 909 Query: 1073 DSKQHNEELQILVREQDDQIKELKET--------KLTFEMNIPKTEGMI-ISSTIEPMSD 1123 + + N ELQ V + Q KET ++ + N+ + M + I+ ++ Sbjct: 910 EMEALNLELQDRVNQLSKQGVSQKETINQLQQQNQMEVKQNLTFLQQMDPLQKQIDHLTR 969 Query: 1124 DANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQ-LETLN 1182 + + L +Q + Q Q KL E+ + K Q ++ N Sbjct: 970 ENRKLQQSNNDFEKAYGKLPTYGSPRKVQNQD--QNQIKKLEDEILQIQYKFQQEIQEKN 1027 Query: 1183 TELTGHDVVNQEQINQLKS-KLEQLNTENDN--LLSTVAELRSSISSAVDQRGFEIAELW 1239 EL ++Q+ +++ KL++++ N +LS + + +++ + Q +I Sbjct: 1028 IELNNIQKQYEQQLEEVRELKLDEISKLEQNCVILSNQLKQQQVVNNELLQNNSQI---- 1083 Query: 1240 KQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQN-K 1298 ++ +Q + +K + + ++Q ES +Q + + E I ++ + + QN + Sbjct: 1084 ERDNSQLSEEIEKLKKQQKLQSQNQESLKQQDQINHECKYIELNQTIGNLQIIINDQNLQ 1143 Query: 1299 LQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQS 1358 L + + H +L+E+ QI+ L E E+ +L ++NQ Sbjct: 1144 LLNFKNHTLDLEEQIKHFEVQIQNLIKEKEELCQIKDSNKSDETFTKNQQNEELDSQNQL 1203 Query: 1359 YKQMQ-EQSILN-INEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEI 1416 +Q++ EQ IL+ +N++ +L++ + + ++ LT L S Sbjct: 1204 MEQLKNEQFILDQVNQDKLKLQQQQIEQGQLIHQQQQVIECQQVEIKRLT--LIESGSVE 1261 Query: 1417 YQKTHEYTITLTQRN--DEFENVRQQLVEYEKRIEDLTYE-KESELAILRLKMHENAN-H 1472 +K + I+ Q N ++ V+Q+ + E + + E K+ E+ L+ K+++N + Sbjct: 1262 QKKESDQNISKLQSNQAEQLLPVQQEEFQVELKQKQKQIEAKDIEIHELKQKLYQNLQLN 1321 Query: 1473 YETMQKESEIERVKLIEELNVKITESVSLNK--QVAELNKALEEEVAKTNEMQTALENQE 1530 E Q+ + + + + E +K ++V+ + ++ ELN+ + + E + L NQ Sbjct: 1322 NELEQQLKDKQAISIALENEIKQLQNVNQTQLQKITELNQDFQRSFEQVEEQKQTLTNQS 1381 Query: 1531 IEIVTLNDEITNLQNMV 1547 + L + +Q V Sbjct: 1382 EQNALLESKCNQMQQNV 1398 Score = 118 bits (283), Expect = 2e-24 Identities = 238/1231 (19%), Positives = 534/1231 (43%), Gaps = 119/1231 (9%) Query: 392 ETLNQDTDKKINK--NEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLI 449 + L QD D++I NE L ++ + K E + S+ DT L Sbjct: 177 QNLIQDKDEEITLIINENGVLNRNLEQMEKSANLSESLHSQIDTLQKQNQNLLIQLSDLQ 236 Query: 450 AQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAE 509 L QQ S I V +++ + + Q+Q + +N ++ ++++ K ++ Sbjct: 237 NHNTLLRQQLQLQSSEIQVSSSSLQLQLQSAPQQQTQDAMNRNVQ----QEMVVLQKDSD 292 Query: 510 EQITQLNDEIDAANKNMIKVKS-NHKLKLKQMQKTID-----NFSKVSDSNKEIVRLTE- 562 Q Q E+ N + + +S N+ L+L Q+T + N ++++ ++I +LT Sbjct: 293 IQALQQTTEVQ--NVQLTQSQSFNNDLQLSYQQETQNTEKDYNQNQINTLKQQIAKLTSD 350 Query: 563 ----ELHHLSQKVAE-------------LEEEKGNLQLH----LVDYDSGRMIESD---- 597 EL H+ K + LE++ +L LH + + +I+ Sbjct: 351 LKECELKHVQVKQVQESTISKLNHDVRLLEQKNEDLILHNNKLINEIKQNELIQQKESTI 410 Query: 598 VYKKMIEME-NLAETRLKAISL-LESQKFD-LVQELHILQQKYDEVEDKLA-DISQLQSD 653 + +K+ E E L E+ + L E QK + +V++L++ Q +++ KL DI++ Q+ Sbjct: 411 ICQKISEFEIQLLESHHQIEDLNQEKQKQERVVEKLNLQMQASKQIQSKLEEDITKYQNF 470 Query: 654 QVC--SEIKSVHLEEQIDALSASKKELALVIENLKLDK--EQLYGTIKDLENDKEDIMNK 709 + ++++V E D+ +S++ + + L D +L I+ ++ E + Sbjct: 471 LISHHKQLEAVTSNESSDSSDSSEETITEKPQQLNFDALCTKLTEQIRLVQLRLEIYEKQ 530 Query: 710 LQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQF-GIDAKIQERDLYIENIE 768 ++ Y QE T +++K+ +E S+ K+ + S++Q +F +A I+++DL IEN+ Sbjct: 531 IKQYKQELHSKTVEIQKLFSEN-SDSNLKV--QRLSQLQPKFDNQEAIIKQKDLTIENLS 587 Query: 769 SELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLA 828 +++K ++++ E + ++ + +L RK +L + +Q +TI+ D ++ Sbjct: 588 QQITKQQAQLHENENKLQQLQIDKETLNRKNVELSNQIQ------IHHTIKNDLQISS-- 639 Query: 829 VLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDL 888 D + +L+ E + + + N N QI L + +N+ D Sbjct: 640 --NKEDPIQHIELMSSEQTSTSIFDQTF----SNINYQILLFTEENTTQIKSILSNKIDN 693 Query: 889 AESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNE 948 E+ + + + L+ +++ H Q L Q ++ + E + + + ++ L E Sbjct: 694 LENNLLRTINKYQKLQEIIQKNYHNIQNLYEQSQQNLIQKENLYQIENQKQQMQRQTLLE 753 Query: 949 KYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKM--NLELIDK-------HVQKQQTQ 999 + + ++QLE Q Q ++NLN ++ ++ L+ +D+ + QT+ Sbjct: 754 EVHQQTILISQLENQQQILSLQLKNLNQQNQDQKQVITQLQQLDEKQKIDDLQMGSNQTK 813 Query: 1000 SPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLEN 1059 + ++ IN+ L +Q + I + +NN S ++ +++ +L Sbjct: 814 LEELQQRTINQEADLKKASEQNTQLEIQVKD-LNNQVQSKLNTINELRQELDSLKNNQTG 872 Query: 1060 MEEE---MQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFE--MNIPKTEGMII 1114 + + +Q+ KQ+L+ +N L ++ +++E++ L + +N +G+ Sbjct: 873 SQFDSIKLQQQQKQILELISNNTNLNQQSQDAQLRLREMEALNLELQDRVNQLSKQGVSQ 932 Query: 1115 SSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTK 1174 TI + N ++ ++ + +E LQ+ N + ++ Y K Sbjct: 933 KETINQLQQQ-NQMEVKQNLTFLQQMDPLQKQIDHLTRENRKLQQS----NNDFEKAYGK 987 Query: 1175 IIQLETLNTELTGHDVVNQEQ--INQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRG 1232 L T + V NQ+Q I +L+ ++ Q+ + + ++I +Q+ Sbjct: 988 ------LPTYGSPRKVQNQDQNQIKKLEDEILQIQYKFQQEIQEKNIELNNIQKQYEQQL 1041 Query: 1233 FEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQ--LLDSVQSSTQEETNKIVTME 1290 E+ EL +++ E + ++L+ Q + ++ S EE K+ + Sbjct: 1042 EEVRELKLDEISKLEQNCVILSNQLKQQQVVNNELLQNNSQIERDNSQLSEEIEKLKKQQ 1101 Query: 1291 QVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXX 1350 ++ S QN+ K++ N + KY ++ I L+ I D+ + Sbjct: 1102 KLQS-QNQESLKQQDQINHECKYIELNQTIGNLQIIINDQNLQLLNFKNHTL-------- 1152 Query: 1351 DLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLE 1410 DL + + + ++Q Q+++ EE Q+K S+ D++ +++E + Sbjct: 1153 DLEEQIKHF-EVQIQNLIKEKEELCQIKDSNKSDETFTKNQQNEELDSQNQLME-----Q 1206 Query: 1411 LKDSE-IYQKTHEYTITLTQRNDEFENV---RQQLVEYEK-RIEDLTYEKESELAILRLK 1465 LK+ + I + ++ + L Q+ E + +QQ++E ++ I+ LT ES + + Sbjct: 1207 LKNEQFILDQVNQDKLKLQQQQIEQGQLIHQQQQVIECQQVEIKRLTLI-ESGSVEQKKE 1265 Query: 1466 MHENANHYETMQKES--EIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQ 1523 +N + ++ Q E +++ + EL K + + + ++ EL + L + + NE++ Sbjct: 1266 SDQNISKLQSNQAEQLLPVQQEEFQVELKQKQKQIEAKDIEIHELKQKLYQNLQLNNELE 1325 Query: 1524 TALENQEIEIVTLNDEITNLQNMVRASSSKI 1554 L++++ + L +EI LQN+ + KI Sbjct: 1326 QQLKDKQAISIALENEIKQLQNVNQTQLQKI 1356 Score = 116 bits (280), Expect = 4e-24 Identities = 227/1152 (19%), Positives = 497/1152 (43%), Gaps = 116/1152 (10%) Query: 493 IKDVNVKD--LIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNF-SK 549 +K VN LI+KL ++ I LN+EI+A+N+ + +KS H + L Q Q I++ S+ Sbjct: 10 LKQVNKNQTLLIQKL---QDDIELLNEEIEASNQQIDTLKSQHHISLSQQQSIIEDLRSE 66 Query: 550 VSDSNKEIVRLTEELHH--LSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMEN 607 + ++ + L + L ++ + + +K N Q + + I+ K + Sbjct: 67 CQNYQQQNMELQSKFTQSVLQNQLLQSKYDKKNKQYKDQIVELKQQIKLSHLKNQDYQRD 126 Query: 608 LAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQ 667 + E R K++ + + L+ +L ++ +++ L D+ Q+ + + +++ ++++ Sbjct: 127 ILELR-KSLDNNKLEICKLIDNSTLLNEQNKQLKANL-DLQQVDYENKIEQYQNL-IQDK 183 Query: 668 IDALSASKKELALVIENL-KLDK-----EQLYGTIKDLENDKEDIMNKLQNYIQENMDLT 721 + ++ E ++ NL +++K E L+ I L+ ++++ +L + N L Sbjct: 184 DEEITLIINENGVLNRNLEQMEKSANLSESLHSQIDTLQKQNQNLLIQLSDLQNHNTLLR 243 Query: 722 DKLEKMSAE-KISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICR 780 +L+ S+E ++S ++ + + QTQ ++ +Q+ + ++ +S++ + Sbjct: 244 QQLQLQSSEIQVSSSSLQLQLQSAPQQQTQDAMNRNVQQEMVVLQK-DSDIQALQQ--TT 300 Query: 781 LEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYT-IQEDELVNRLAVLMDHDRVVEK 839 +++ + + + ++ + + SY QE Q +Y Q + L ++A L + E Sbjct: 301 EVQNVQLTQSQSFNNDLQL----SYQQETQNTEKDYNQNQINTLKQQIAKLTSDLKECEL 356 Query: 840 QLLEIEH-ENKELQKKN-QILLEENQNLQISLSDMQQHYNALVEKANRTDL-AESESTKY 896 + ++++ + + K N + L E +N D+ H N L+ + + +L + EST Sbjct: 357 KHVQVKQVQESTISKLNHDVRLLEQKN-----EDLILHNNKLINEIKQNELIQQKESTII 411 Query: 897 QTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEY 956 ++ + E L H+ + L +K+K+ +E + N Q++++ + + L E K + Sbjct: 412 CQKISEFEIQLLESHHQIEDLNQEKQKQERVVE-KLNLQMQASKQIQSKLEEDITKYQNF 470 Query: 957 VTQLEAQLQEYKNNIENLNMN------VEELNKMNLELIDKHVQKQQTQSPDYTEQYINE 1010 + QL+ +N + + + E+ ++N + + + +Q E Y + Sbjct: 471 LISHHKQLEAVTSNESSDSSDSSEETITEKPQQLNFDALCTKLTEQIRLVQLRLEIYEKQ 530 Query: 1011 INKLNALLKQKDEEIIAL--NQKINNAQVSYMSMV----SDYESKLAQFTTKLENMEEEM 1064 I + L K EI L +N +V +S + + E+ + Q +EN+ +++ Sbjct: 531 IKQYKQELHSKTVEIQKLFSENSDSNLKVQRLSQLQPKFDNQEAIIKQKDLTIENLSQQI 590 Query: 1065 QRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKT--EGMIISST----- 1117 + QL +++ ++LQI D + K +L+ ++ I T + ISS Sbjct: 591 TKQQAQLHENENKLQQLQI-----DKETLNRKNVELSNQIQIHHTIKNDLQISSNKEDPI 645 Query: 1118 --IEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTK- 1174 IE MS + + + + EE Q +S+L + L L K Sbjct: 646 QHIELMSSEQTSTSIFDQTFSNINYQILLFTEENTTQIKSILSNKIDNLENNLLRTINKY 705 Query: 1175 -----IIQLETLNT----ELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSIS 1225 IIQ N E + +++ +E + Q++++ +Q+ + LL V + IS Sbjct: 706 QKLQEIIQKNYHNIQNLYEQSQQNLIQKENLYQIENQKQQM--QRQTLLEEVHQQTILIS 763 Query: 1226 SAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNK 1285 +Q+ +I L ++L Q+ D + ++ QL + K Q +D +Q + + Sbjct: 764 QLENQQ--QILSLQLKNLNQQNQD----QKQVITQLQQLDEK--QKIDDLQMGSNQ---- 811 Query: 1286 IVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXX 1345 ++ LQ + ++E L+ E+ + Q++ L ++++ + Sbjct: 812 ----TKLEELQQRTINQEADLKKASEQNTQLEIQVKDLNNQVQSK---LNTINELRQELD 864 Query: 1346 XXXXXDLRTENQSYK-QMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLE 1404 ++ S K Q Q++ IL + N L + S R+ + EA LE Sbjct: 865 SLKNNQTGSQFDSIKLQQQQKQILELISNNTNLNQQS-------QDAQLRLREMEALNLE 917 Query: 1405 LTHQL-ELKDSEIYQKTHEYTITLTQRNDEFE-----NVRQQLVEYEKRIEDLTYEKESE 1458 L ++ +L + QK TI Q+ ++ E QQ+ +K+I+ LT E Sbjct: 918 LQDRVNQLSKQGVSQKE---TINQLQQQNQMEVKQNLTFLQQMDPLQKQIDHLTRENRK- 973 Query: 1459 LAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAK 1518 L+ ++ Y + +V+ ++ +K E L Q + + ++E+ + Sbjct: 974 ---LQQSNNDFEKAYGKLPTYGSPRKVQNQDQNQIKKLEDEILQIQY-KFQQEIQEKNIE 1029 Query: 1519 TNEMQTALENQEIEIVTLN-DEITNL-QNMVRASSSKIQKHVSFASDTKQGRDEQLDNTM 1576 N +Q E Q E+ L DEI+ L QN V S+ Q+ V + + DN+ Sbjct: 1030 LNNIQKQYEQQLEEVRELKLDEISKLEQNCVILSNQLKQQQVVNNELLQNNSQIERDNSQ 1089 Query: 1577 NKELLDAVPRAE 1588 E ++ + + + Sbjct: 1090 LSEEIEKLKKQQ 1101 Score = 113 bits (272), Expect = 4e-23 Identities = 252/1274 (19%), Positives = 549/1274 (43%), Gaps = 127/1274 (9%) Query: 388 QLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDT 447 QLS + Q+T+K N+N+I L+ I L DL + E + Sbjct: 318 QLSYQQETQNTEKDYNQNQINTLKQQIAKLTSDLKECELKHVQVKQVQESTISKLNHDVR 377 Query: 448 LIAQ----LQLEHQQ---HMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKD 500 L+ Q L L + + ++ LI +T +I++ + QL E + +I+D+N + Sbjct: 378 LLEQKNEDLILHNNKLINEIKQNELIQQKESTIICQKISEFEIQLL-ESHHQIEDLNQEK 436 Query: 501 -----LIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNK 555 ++EKL + Q+ +++ +H +L+ + T + S SDS++ Sbjct: 437 QKQERVVEKLNLQMQASKQIQSKLEEDITKYQNFLISHHKQLEAV--TSNESSDSSDSSE 494 Query: 556 EIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSG-RMIESDVYKKMIEMENLAETRLK 614 E + + + +L E+ +QL L Y+ + + +++ K +E++ L Sbjct: 495 ETITEKPQQLNFDALCTKLTEQIRLVQLRLEIYEKQIKQYKQELHSKTVEIQKLFS---- 550 Query: 615 AISLLESQKFDL-VQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSA 673 E+ +L VQ L LQ K+D E A I Q ++ +L +QI A Sbjct: 551 -----ENSDSNLKVQRLSQLQPKFDNQE---AIIKQ-------KDLTIENLSQQITKQQA 595 Query: 674 SKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKIS 733 E ++ L++DKE L +L N + I + ++N +Q + + D ++ + Sbjct: 596 QLHENENKLQQLQIDKETLNRKNVELSNQIQ-IHHTIKNDLQISSNKEDPIQHIELMSSE 654 Query: 734 ELLAKINHEEQSKIQTQ---FGIDAKIQERDLY---IENIESELSKYKSRICRLEESIAV 787 + I + S I Q F + Q + + I+N+E+ L + ++ +L+E + Sbjct: 655 QTSTSIFDQTFSNINYQILLFTEENTTQIKSILSNKIDNLENNLLRTINKYQKLQE---I 711 Query: 788 MEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHE 847 ++ ++++ +Q L +K+ Y + Q+ ++ + + H + + LE + + Sbjct: 712 IQKNYHNIQNLYEQSQQNLIQKENLY-QIENQKQQMQRQTLLEEVHQQTILISQLENQQQ 770 Query: 848 NKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAE-SESTKYQT-QLRDL-- 903 LQ KN L ++NQ+ + ++ +QQ L EK DL S TK + Q R + Sbjct: 771 ILSLQLKN--LNQQNQDQKQVITQLQQ----LDEKQKIDDLQMGSNQTKLEELQQRTINQ 824 Query: 904 ESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVT--QLE 961 E++LK+ + ++ L +Q K ++ + NT E + N + + + Q + Sbjct: 825 EADLKKASEQNTQLEIQVKDLNNQVQSKLNTINELRQELDSLKNNQTGSQFDSIKLQQQQ 884 Query: 962 AQLQEYKNNIENLN-------MNVEELNKMNLELIDK--HVQKQ-----------QTQSP 1001 Q+ E +N NLN + + E+ +NLEL D+ + KQ Q Q+ Sbjct: 885 KQILELISNNTNLNQQSQDAQLRLREMEALNLELQDRVNQLSKQGVSQKETINQLQQQNQ 944 Query: 1002 DYTEQYINEINKLNALLKQKDE---EIIALNQKINNAQVSYMSMVSDYESKLAQFT--TK 1056 +Q + + +++ L KQ D E L Q N+ + +Y + + + Q + Sbjct: 945 MEVKQNLTFLQQMDPLQKQIDHLTRENRKLQQSNNDFEKAYGKLPTYGSPRKVQNQDQNQ 1004 Query: 1057 LENMEEEMQRVS-KQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIIS 1115 ++ +E+E+ ++ K + ++ N EL + ++ + Q++E++E KL E++ + +I+S Sbjct: 1005 IKKLEDEILQIQYKFQQEIQEKNIELNNIQKQYEQQLEEVRELKLD-EISKLEQNCVILS 1063 Query: 1116 STIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQ---SAKLNTELQ-EC 1171 + ++ N + ++ EE E ++++ LQ Q S K ++ EC Sbjct: 1064 NQLK--QQQVVNNELLQNNSQIERDNSQLSEEIEKLKKQQKLQSQNQESLKQQDQINHEC 1121 Query: 1172 -YTKIIQ--------LETLNTELTG---HDVVNQEQINQLKSKLEQLNTENDNLLSTVAE 1219 Y ++ Q + N +L H + +EQI + +++ L E + L Sbjct: 1122 KYIELNQTIGNLQIIINDQNLQLLNFKNHTLDLEEQIKHFEVQIQNLIKEKEELCQIKDS 1181 Query: 1220 LRSSISSAVDQRGFEIA---ELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQ 1276 +S + +Q+ E+ +L +Q ++ Q + +L++Q E QL+ Q Sbjct: 1182 NKSDETFTKNQQNEELDSQNQLMEQLKNEQFILDQVNQDKLKLQQQQIEQG--QLIHQQQ 1239 Query: 1277 S--STQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQI--EILRSEIEDEKV 1332 Q+ K +T+ + S++ K ++ ++++ LQ A+ + + E + E++ ++ Sbjct: 1240 QVIECQQVEIKRLTLIESGSVEQK-KESDQNISKLQSNQAEQLLPVQQEEFQVELKQKQK 1298 Query: 1333 AFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXX 1392 +L+ N+ +Q++++ ++I EN ++K+ Sbjct: 1299 QIEAKDIEIHELKQKLYQNLQLNNELEQQLKDKQAISIALEN-EIKQLQNVNQTQLQKIT 1357 Query: 1393 XRVNDAEAKVLELTHQLELKDSEIYQKTH-EYTITLTQRND-EFENVRQQLVEYEKRIED 1450 D + ++ Q + ++ Q E Q+N + + L++ +++E Sbjct: 1358 ELNQDFQRSFEQVEEQKQTLTNQSEQNALLESKCNQMQQNVMKIQTQNNSLIQINQQLES 1417 Query: 1451 LTYEKESELAILRLKMHENANHYE----TMQKESEIERVKLIEELNVKITESVSLNKQVA 1506 T E++ + ++ E + + +Q E + ++KL+++ N + + + Sbjct: 1418 -TLEQQQHVNAQIIQKQEQSFQIQLDKLNIQLEDQQNQLKLLQQENGEYKQEIE-----K 1471 Query: 1507 ELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQ 1566 +N + E K NE+ + + +I L D+I+ + + ++I + + Q Sbjct: 1472 IMNDQKQWEQNKLNELVQVKKESQGQIQKLMDQISRAEGLNVEHQNEILEMDNVIKKLIQ 1531 Query: 1567 GRDEQLDNTMNKEL 1580 +D+ ++N M ++L Sbjct: 1532 EKDKNINNDMIEQL 1545 >UniRef50_Q22NP6 Cluster: Putative uncharacterized protein; n=1; Tetrahymena thermophila SB210|Rep: Putative uncharacterized protein - Tetrahymena thermophila SB210 Length = 1674 Score = 134 bits (323), Expect = 3e-29 Identities = 212/1067 (19%), Positives = 462/1067 (43%), Gaps = 94/1067 (8%) Query: 334 LNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSET 393 LN Q Q N + ++ G + + S SK + + + + + + SS Sbjct: 479 LNSQ-PQVNSQQKSNQTYSGQQKQLQQSLSKNNNTSNFFNNVQKNSINNNNHNNDNSSMW 537 Query: 394 LNQ--DTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQ 451 LNQ + D++I++NE +Q +DK + EK+ + + Sbjct: 538 LNQYENMDREIHQNEHQ-----LQQERDQFLDKIRDLEEKNKELRQFEKENIQLKQQLYE 592 Query: 452 LQLEHQQHMEGPSLIHVGTNT----EDVNEIAKVQEQLKQELNDEIKDV-NVKDLIEKLK 506 +Q++ ++ + T +D N I ++Q +++++ +IK N++D+ Sbjct: 593 IQIKSEEDKNHEVTMFKDDTTIFSQKDYN-IQRLQSLIQEDVESKIKTFSNIEDIKILCI 651 Query: 507 SAEEQITQLNDEID-AANKNMIKVKSNHKLKL----KQMQKTIDNFSKVSDSNKEIVRLT 561 E +I QL ID N+ ++ S + + +Q + + + +KEI++ Sbjct: 652 EKEIEIEQLKKRIDDLVNQQSSQILSGTQPDIVTQNADLQNELMQMKQNNQKSKEIIQQK 711 Query: 562 E-ELHHLSQKVA--ELEEEKGNLQLHLVDYDSG--RMIESDVYKKMIEMENLAETRLKAI 616 + E+ L + +LE +K LQ + S R I + + E N A T++ Sbjct: 712 QLEIEQLKSVIQKQQLESQKA-LQTGISGMPSTERRSISYRMQESSRE-NNQANTQIYEQ 769 Query: 617 SLLESQKFDLVQELHILQQKYDE-VEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASK 675 + E K + + +LH +++ V+++ I+ L+ + + + + LE + ++ Sbjct: 770 RIQE--KDNQIGQLHTKREELKTMVQERDNQINHLRKEYITVQGRLSKLESENFDINRKY 827 Query: 676 KELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISEL 735 KEL +I++ L+ E + + E+I +LQ + N + L + + I+E Sbjct: 828 KELQSLIQSKTLECEDWKNKFIETDRKIENIP-QLQIELNRNQETIKDLNQRIEQLINE- 885 Query: 736 LAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSL 795 N + +I +FG++ +I E++ IEN+ +++++ K +I + + +++ S Sbjct: 886 ----NSGFKLRIGEKFGVENRINEKEREIENMITKINEQKKQIQEFQAKVVELQNIEKSK 941 Query: 796 ERKADQLGSYLQEKQKAYSEYTIQEDEL----------VNRLAVLMDHDRVVEKQLLEIE 845 E Q + +E + Q D++ + +++ + + ++K++L+++ Sbjct: 942 EILFKQYKLFCEENNSLKQDIQSQLDKIQSLENQVQENIQDISLYQNENMQIKKEILQLK 1001 Query: 846 HENKELQKKNQILLEENQNLQISLSDMQQHYNAL-----------VEKANRTDLAESEST 894 EN +LQ Q ++E ++LQ + + N L E+A + E+ Sbjct: 1002 LENSQLQASLQDAVQEKKDLQSENEKLNETVNQLKQNLSNTLSDTKERAQKVSYLTHENQ 1061 Query: 895 KYQTQLRDLESNLKRITHEHQTL---IVQKKKEIEDL-EI--EFNTQIESAIRDKKVLNE 948 +L+ + L+R+ E + I Q+K +E+ EI +F + I D K L Sbjct: 1062 NLANELKKNKQELERVRLEKNNILYEINQQKLSVENYNEIIKKFEDKESKQIEDMKQLER 1121 Query: 949 KYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQ----KQQTQSPDYT 1004 +++K + V QL L E ++ ++N + ++E N + LE + + Q + Q Q+ + Sbjct: 1122 EFDKKQKDVQQLNKLLSEQESRLQNQIIQIQEQN-IQLECLKQREQDLLNQIQQQNDQFA 1180 Query: 1005 EQYIN---EINK-----LNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTK 1056 + IN EIN+ LNA ++ +++I N+K + Y ++ + Sbjct: 1181 IEGINLRMEINEKMSQMLNAEKEKFNQQINIANKKYEQKDDEINQLTQKYNQEITENDKL 1240 Query: 1057 LENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMI--I 1114 ++ +EE Q++++Q + ++L+ L +E QI ++ +T E N K + I I Sbjct: 1241 IKKVEEYQQKLNEQFREMTDTKQKLESLQKEYQQQIHKIIKTN---EQNQKKDQNKIEEI 1297 Query: 1115 SSTIEPMSDDANNVDXXXXXXXXXX----XXLKVQEEEEFIQERSVLQEQSAKLNTELQE 1170 S + + ++ K + + IQ+ Q Q + E ++ Sbjct: 1298 SEQLRAAIQEKETIEQRLKSKREDAQIWEEKYKKLLQAKEIQQYFDYQNQLTNIKEESEQ 1357 Query: 1171 CYTKIIQLETLNTELTGHDVVNQEQINQ-LKSKLEQLNTENDNLLSTVAELRSSISSAVD 1229 I+ E +++ E+ NQ L+ +L+++ + S +E + + Sbjct: 1358 YNQMILNAYQQQIEEKNNEIKCLEEENQSLQQQLQKMVLLQNETYSQQSEKCKKLQEEIS 1417 Query: 1230 QRGFEI--AELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIV 1287 QR +I + L + + D + +++ ++Q S E++ E L Q S E+ N+ + Sbjct: 1418 QREIQIETQTIEINQLKKYKLDQESEKYQWQMQKSKIENQLEVL--QKQYSELEKFNQGL 1475 Query: 1288 T--MEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKV 1332 ++Q S ++QD E ++ + +I Q+EI +IE E++ Sbjct: 1476 NSLLQQRQSEFQQIQDDYERVKKENRDHQRIIKQMEI---QIESEQL 1519 Score = 125 bits (302), Expect = 9e-27 Identities = 218/1070 (20%), Positives = 451/1070 (42%), Gaps = 113/1070 (10%) Query: 228 MEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXX 287 M+ E + +L ++ + +I LEE NK E +FE E+ +L Q+L + Sbjct: 544 MDREIHQNEHQLQQERDQFLDKIRDLEEKNK--ELRQFE--KENIQLKQQLYEIQIKSEE 599 Query: 288 XXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELEN 347 + K ++ I+ SL ++ K +E + +I KE+E Sbjct: 600 DKNHEVTMFKDDTTIFSQKDYNIQRLQSLIQEDVESKIKTFSNIEDI--KILCIEKEIE- 656 Query: 348 KLATMGTESKAVSSPSKKGSPLISRKSGR---NTASKMKSPWSQLSSETLNQDTDKKINK 404 + K+ L++++S + T + + + L +E + + + +K Sbjct: 657 -----------IEQLKKRIDDLVNQQSSQILSGTQPDIVTQNADLQNELMQMKQNNQKSK 705 Query: 405 NEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPS 464 I + ++ I+ L K ++ K+ + S+K + ++ ++Q +++ + + Sbjct: 706 EIIQQKQLEIEQL-KSVIQKQQLESQKALQTGISGMPSTERRSISYRMQESSRENNQANT 764 Query: 465 LIHVGTNTEDVNEIAKV---QEQLK---QELNDEIKD-----VNVKDLIEKLKSAEEQIT 513 I+ E N+I ++ +E+LK QE +++I + V+ + KL+S I Sbjct: 765 QIYEQRIQEKDNQIGQLHTKREELKTMVQERDNQINHLRKEYITVQGRLSKLESENFDIN 824 Query: 514 QLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAE 573 + E+ + ++ + K K + + I+N ++ E+ R E + L+Q++ + Sbjct: 825 RKYKELQSLIQSKTLECEDWKNKFIETDRKIENIPQLQI---ELNRNQETIKDLNQRIEQ 881 Query: 574 LEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLA---ETRLKAIS-----LLESQKFD 625 L E +L + + +E+ + +K E+EN+ + K I ++E Q + Sbjct: 882 LINENSGFKLRIGEKFG---VENRINEKEREIENMITKINEQKKQIQEFQAKVVELQNIE 938 Query: 626 LVQELHILQQK-YDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALV--- 681 +E+ Q K + E + L Q Q D++ S V +E I +S + E + Sbjct: 939 KSKEILFKQYKLFCEENNSLKQDIQSQLDKIQSLENQV--QENIQDISLYQNENMQIKKE 996 Query: 682 IENLKLDKEQLYGTIKDLENDKEDI------MNKLQNYIQENMDLTDKLEKMSAEKISEL 735 I LKL+ QL +++D +K+D+ +N+ N +++N+ T K A+K+S L Sbjct: 997 ILQLKLENSQLQASLQDAVQEKKDLQSENEKLNETVNQLKQNLSNTLSDTKERAQKVSYL 1056 Query: 736 ------LA---KINHEEQSKIQTQFG-IDAKIQERDLYIENIESELSKYKSRICRLEESI 785 LA K N +E +++ + I +I ++ L +EN + K++ + + E + Sbjct: 1057 THENQNLANELKKNKQELERVRLEKNNILYEINQQKLSVENYNEIIKKFEDKESKQIEDM 1116 Query: 786 AVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIE 845 +E ++ QL L E++ IQ E +L L ++ + L +I+ Sbjct: 1117 KQLEREFDKKQKDVQQLNKLLSEQESRLQNQIIQIQEQNIQLECLKQREQDL---LNQIQ 1173 Query: 846 HENKELQKKN-QILLEENQNLQISLSDMQQHYNALVEKANRT-----DLAESESTKYQTQ 899 +N + + + +E N+ + L+ ++ +N + AN+ D + KY + Sbjct: 1174 QQNDQFAIEGINLRMEINEKMSQMLNAEKEKFNQQINIANKKYEQKDDEINQLTQKYNQE 1233 Query: 900 LRDLESNLKRITHEHQTL------IVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKN 953 + + + +K++ Q L + K+++E L+ E+ QI I+ + +K + Sbjct: 1234 ITENDKLIKKVEEYQQKLNEQFREMTDTKQKLESLQKEYQQQIHKIIKTNEQNQKKDQNK 1293 Query: 954 IEYVT-QLEAQLQEYKNNIENLNMNVEELN----KMNLELIDKHVQK------QQTQSPD 1002 IE ++ QL A +QE + + L E+ K L K +Q+ Q T + Sbjct: 1294 IEEISEQLRAAIQEKETIEQRLKSKREDAQIWEEKYKKLLQAKEIQQYFDYQNQLTNIKE 1353 Query: 1003 YTEQYINEI-NKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENME 1061 +EQY I N +++K+ EI L ++ + Q MV +Q + K + ++ Sbjct: 1354 ESEQYNQMILNAYQQQIEEKNNEIKCLEEENQSLQQQLQKMVLLQNETYSQQSEKCKKLQ 1413 Query: 1062 EEMQR--------------VSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIP 1107 EE+ + + K LD + + Q+ + ++Q++ L++ E Sbjct: 1414 EEISQREIQIETQTIEINQLKKYKLDQESEKYQWQMQKSKIENQLEVLQKQYSELEKFNQ 1473 Query: 1108 KTEGMIIS--STIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLN 1165 ++ S + + DD V +++Q E E +Q + LQ Q Sbjct: 1474 GLNSLLQQRQSEFQQIQDDYERVKKENRDHQRIIKQMEIQIESEQLQNKR-LQSQKKDDE 1532 Query: 1166 TELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLS 1215 Q ++ LE +++ V + +QIN LK + N E N LS Sbjct: 1533 NIKQNLIERLKSLEEDSSQQNKRFVESLQQINGLKDSFKTKNNELTNFLS 1582 Score = 121 bits (291), Expect = 2e-25 Identities = 197/1097 (17%), Positives = 456/1097 (41%), Gaps = 74/1097 (6%) Query: 453 QLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQI 512 Q EHQ E + + E+ N+ + E+ +L ++ ++ +K +K ++ Sbjct: 550 QNEHQLQQERDQFLDKIRDLEEKNKELRQFEKENIQLKQQLYEIQIKSEEDK----NHEV 605 Query: 513 TQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVA 572 T D+ ++ ++ L + ++ I FS + D + E+ L +++ Sbjct: 606 TMFKDDTTIFSQKDYNIQRLQSLIQEDVESKIKTFSNIEDIKILCIEKEIEIEQLKKRID 665 Query: 573 ELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHI 632 +L ++ + L D +D+ ++++M+ + K+ +++ ++ ++ Q + Sbjct: 666 DLVNQQSSQILSGTQPDIVTQ-NADLQNELMQMK---QNNQKSKEIIQQKQLEIEQLKSV 721 Query: 633 LQQKYDEVEDKL-ADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQ 691 +Q++ E + L IS + S +E +S+ Q + ++ + + ++ +K+ Sbjct: 722 IQKQQLESQKALQTGISGMPS----TERRSISYRMQESSRENNQANTQIYEQRIQ-EKDN 776 Query: 692 LYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQF 751 G L +E+ L+ +QE + + L K + L+K+ E F Sbjct: 777 QIG---QLHTKREE----LKTMVQERDNQINHLRKEYIT-VQGRLSKLESEN-------F 821 Query: 752 GIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQK 811 I+ K +E I++ E +K++ + I + + L R + + Q ++ Sbjct: 822 DINRKYKELQSLIQSKTLECEDWKNKFIETDRKIENIPQLQIELNRNQETIKDLNQRIEQ 881 Query: 812 AYSEYTIQEDELVNRLAV---LMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQIS 868 +E + + + + V + + +R +E + +I + K++Q+ Q + E QN++ S Sbjct: 882 LINENSGFKLRIGEKFGVENRINEKEREIENMITKINEQKKQIQEF-QAKVVELQNIEKS 940 Query: 869 LSDMQQHYNALVEKAN--RTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIE 926 + + Y E+ N + D+ +S+ K Q+ ++ N++ I+ +Q +Q KKEI Sbjct: 941 KEILFKQYKLFCEENNSLKQDI-QSQLDKIQSLENQVQENIQDISL-YQNENMQIKKEIL 998 Query: 927 DLEIEFNTQIESAIRD----KKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELN 982 L++E N+Q++++++D KK L + EK E V QL+ L ++ + V L Sbjct: 999 QLKLE-NSQLQASLQDAVQEKKDLQSENEKLNETVNQLKQNLSNTLSDTKERAQKVSYLT 1057 Query: 983 KMNLELIDKHVQKQQTQSPDYTEQ--YINEINKLNALLKQKDEEIIALNQKINNAQVSYM 1040 N L ++ + +Q E+ + EIN+ ++ +E I K + Sbjct: 1058 HENQNLANELKKNKQELERVRLEKNNILYEINQQKLSVENYNEIIKKFEDKESKQIEDMK 1117 Query: 1041 SMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKL 1100 + +++ K + + E+ R+ Q++ ++ N +L+ L + + D + ++++ Sbjct: 1118 QLEREFDKKQKDVQQLNKLLSEQESRLQNQIIQIQEQNIQLECLKQREQDLLNQIQQQND 1177 Query: 1101 TFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQ 1160 F + EG+ + I N + K +++++ I + + Sbjct: 1178 QFAI-----EGINLRMEINEKMSQMLNAEKEKFNQQINIANKKYEQKDDEINQLT----- 1227 Query: 1161 SAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAEL 1220 K N E+ E I ++E +L ++ K KLE L E + + + Sbjct: 1228 -QKYNQEITENDKLIKKVEEYQQKLNEQF----REMTDTKQKLESLQKEYQQQIHKIIKT 1282 Query: 1221 RSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQ 1280 + EI+E + + ++E Q+ + + R +E KY++LL + + Sbjct: 1283 NEQNQKKDQNKIEEISEQLRAAIQEKETIEQRLKSK-REDAQIWEEKYKKLLQA-----K 1336 Query: 1281 EETNKIVTMEQVTSLQNKLQDKEEHLRNL-QEKYADVINQIEILRSEIEDEKVAFXXXXX 1339 E Q+T+++ + + + + N Q++ + N+I+ L E + + Sbjct: 1337 EIQQYFDYQNQLTNIKEESEQYNQMILNAYQQQIEEKNNEIKCLEEENQSLQQQLQKMVL 1396 Query: 1340 XXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAE 1399 + + Q + Q E N QLKK + + E Sbjct: 1397 LQNETYSQQSEKCKKLQEEISQREIQIETQTIEIN-QLKKYKLDQESEKYQWQMQKSKIE 1455 Query: 1400 AKVLELTHQ---LELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKE 1456 ++ L Q LE + + + Q D++E V+++ ++++ I+ + + E Sbjct: 1456 NQLEVLQKQYSELEKFNQGLNSLLQQRQSEFQQIQDDYERVKKENRDHQRIIKQMEIQIE 1515 Query: 1457 SELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEV 1516 SE L+ K ++ + K++ IER+K +EE + + ++ + + ++N + Sbjct: 1516 SEQ--LQNKRLQSQKKDDENIKQNLIERLKSLEEDSSQ--QNKRFVESLQQINGLKDSFK 1571 Query: 1517 AKTNEMQTALENQEIEI 1533 K NE+ L +I Sbjct: 1572 TKNNELTNFLSKTNKQI 1588 Score = 93.9 bits (223), Expect = 3e-17 Identities = 171/913 (18%), Positives = 397/913 (43%), Gaps = 85/913 (9%) Query: 685 LKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKIN-HEE 743 L+ +++Q I+DLE ++ L+ + +EN+ L +L ++ + + ++ ++ Sbjct: 555 LQQERDQFLDKIRDLEEKNKE----LRQFEKENIQLKQQLYEIQIKSEEDKNHEVTMFKD 610 Query: 744 QSKIQTQFGIDAKIQE-RDLYIENIESELSKYKS----RICRLEESIAVMEDRRYSLERK 798 + I +Q D IQ + L E++ES++ + + +I +E+ I + E + ++ Sbjct: 611 DTTIFSQK--DYNIQRLQSLIQEDVESKIKTFSNIEDIKILCIEKEIEI-EQLKKRIDDL 667 Query: 799 ADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDR----VVEKQLLEIEHENKELQKK 854 +Q S + + + Q +L N L + +++ +++++ LEIE +QK+ Sbjct: 668 VNQQSSQILSGTQP--DIVTQNADLQNELMQMKQNNQKSKEIIQQKQLEIEQLKSVIQKQ 725 Query: 855 NQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTK---YQTQLRDLESNLKRI- 910 LE + LQ +S M + + E+ Y+ ++++ ++ + ++ Sbjct: 726 Q---LESQKALQTGISGMPSTERRSISYRMQESSRENNQANTQIYEQRIQEKDNQIGQLH 782 Query: 911 --THEHQTLIVQKKKEIEDLEIEFNT---QIESAIRDKKVLNEKYEKNIEYVTQLEAQLQ 965 E +T++ ++ +I L E+ T ++ + +N KY++ + + + Sbjct: 783 TKREELKTMVQERDNQINHLRKEYITVQGRLSKLESENFDINRKYKELQSLIQSKTLECE 842 Query: 966 EYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEI 1025 ++KN + +E + ++ +EL Q+ EQ INE + + +K Sbjct: 843 DWKNKFIETDRKIENIPQLQIEL--NRNQETIKDLNQRIEQLINENSGFKLRIGEKFGVE 900 Query: 1026 IALNQKINNAQVSYMSMVSDYESKLAQFTTK---LENMEEEMQRVSKQLLDSKQHNEELQ 1082 +N+K + + ++ +++ + ++ +F K L+N+E+ + + KQ + N L+ Sbjct: 901 NRINEKEREIE-NMITKINEQKKQIQEFQAKVVELQNIEKSKEILFKQYKLFCEENNSLK 959 Query: 1083 ILVREQDDQIKELKET--KLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXX 1140 ++ Q D+I+ L+ + ++++ + E M I I + + + + Sbjct: 960 QDIQSQLDKIQSLENQVQENIQDISLYQNENMQIKKEILQLKLENSQLQASLQDA----- 1014 Query: 1141 XLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLK 1200 VQE+++ E L E +L L + + + LT + ++ + K Sbjct: 1015 ---VQEKKDLQSENEKLNETVNQLKQNLSNTLSDTKERAQKVSYLTHENQNLANELKKNK 1071 Query: 1201 SKLEQLNTENDNLLSTVAELRSSISSAVDQ-RGFEIAELWK-QHLAQREADFQKTEHELR 1258 +LE++ E +N+L + + + S+ + + + FE E + + + Q E +F K + +++ Sbjct: 1072 QELERVRLEKNNILYEINQQKLSVENYNEIIKKFEDKESKQIEDMKQLEREFDKKQKDVQ 1131 Query: 1259 VQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVIN 1318 QL+ S+ E L + QE+ Q+ L+ + QD ++ +++A I Sbjct: 1132 -QLNKLLSEQESRLQNQIIQIQEQNI------QLECLKQREQDLLNQIQQQNDQFA--IE 1182 Query: 1319 QIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLK 1378 I LR EI +EK++ + N+ Y+Q ++ I + ++ Q Sbjct: 1183 GIN-LRMEI-NEKMS-----QMLNAEKEKFNQQINIANKKYEQKDDE-INQLTQKYNQEI 1234 Query: 1379 KSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVR 1438 + ++N+ ++ + +LE E Q+ H+ T Q + +N Sbjct: 1235 TENDKLIKKVEEYQQKLNEQFREMTDTKQKLESLQKEYQQQIHKIIKTNEQNQKKDQN-- 1292 Query: 1439 QQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITES 1498 ++ E +++ EKE+ L+ K E+A +E K KL++ ++ + Sbjct: 1293 -KIEEISEQLRAAIQEKETIEQRLKSK-REDAQIWEEKYK-------KLLQAKEIQ--QY 1341 Query: 1499 VSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHV 1558 Q+ + +EE + N+M Q+IE N+EI L+ ++ ++QK V Sbjct: 1342 FDYQNQLTNI----KEESEQYNQMILNAYQQQIE--EKNNEIKCLEEENQSLQQQLQKMV 1395 Query: 1559 SFASDTKQGRDEQ 1571 ++T + E+ Sbjct: 1396 LLQNETYSQQSEK 1408 Score = 91.5 bits (217), Expect = 2e-16 Identities = 144/747 (19%), Positives = 308/747 (41%), Gaps = 76/747 (10%) Query: 839 KQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQT 898 + LL + + QK NQ + + LQ SLS N + + + + Sbjct: 476 QSLLNSQPQVNSQQKSNQTYSGQQKQLQQSLSKNNNTSNFFNNVQKNSINNNNHNNDNSS 535 Query: 899 QLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVT 958 + N+ R H+++ + Q++ + D +I K L + ++NI+ Sbjct: 536 MWLNQYENMDREIHQNEHQLQQERDQFLD-------KIRDLEEKNKELRQFEKENIQLKQ 588 Query: 959 QL-EAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYI---NEINKL 1014 QL E Q++ ++ + M ++ + + D ++Q+ Q+ + E I + I + Sbjct: 589 QLYEIQIKSEEDKNHEVTMFKDDTTIFSQK--DYNIQRLQSLIQEDVESKIKTFSNIEDI 646 Query: 1015 NALLKQKDEEIIALNQKINNAQVSYMSMV-----SDYESKLAQFTTKLENMEEEMQRVSK 1069 L +K+ EI L ++I++ S + D ++ A +L M++ Q+ SK Sbjct: 647 KILCIEKEIEIEQLKKRIDDLVNQQSSQILSGTQPDIVTQNADLQNELMQMKQNNQK-SK 705 Query: 1070 QLLDSKQHN-EELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNV 1128 +++ KQ E+L+ ++++Q + ++ +T ++ +P TE IS ++ S + N Sbjct: 706 EIIQQKQLEIEQLKSVIQKQQLESQKALQTGIS---GMPSTERRSISYRMQESSRENNQA 762 Query: 1129 DXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGH 1188 + Q E+ IQE+ Q +L+T+ +E T + + + L Sbjct: 763 NT--------------QIYEQRIQEKD---NQIGQLHTKREELKTMVQERDNQINHL--- 802 Query: 1189 DVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREA 1248 +E I ++ +L +L +EN ++ EL+S I S + E WK + + Sbjct: 803 ---RKEYIT-VQGRLSKLESENFDINRKYKELQSLIQSKTLE-----CEDWKNKFIETDR 853 Query: 1249 DFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRN 1308 + +L+++L+ + + L ++ E + + + + ++N++ +KE + N Sbjct: 854 KIENIP-QLQIELNRNQETIKDLNQRIEQLINENSGFKLRIGEKFGVENRINEKEREIEN 912 Query: 1309 LQEKYADVINQIEILRSE------IEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQM 1362 + K + QI+ +++ IE K D++++ + + Sbjct: 913 MITKINEQKKQIQEFQAKVVELQNIEKSKEILFKQYKLFCEENNSLKQDIQSQLDKIQSL 972 Query: 1363 QEQSILNINE------ENAQLKKSSXXXXXXXXXXXXRVNDA----------EAKVLELT 1406 + Q NI + EN Q+KK + DA K+ E Sbjct: 973 ENQVQENIQDISLYQNENMQIKKEILQLKLENSQLQASLQDAVQEKKDLQSENEKLNETV 1032 Query: 1407 HQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKM 1466 +QL+ S T E ++ E +N+ +L + ++ +E + EK + L + + Sbjct: 1033 NQLKQNLSNTLSDTKERAQKVSYLTHENQNLANELKKNKQELERVRLEKNNILYEINQQK 1092 Query: 1467 HENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTAL 1526 N+ E ++K + E K IE++ E K V +LNK L E+ ++ + Sbjct: 1093 LSVENYNEIIKKFEDKES-KQIEDMKQLEREFDKKQKDVQQLNKLLSEQESRLQNQIIQI 1151 Query: 1527 ENQEIEIVTLNDEITNLQNMVRASSSK 1553 + Q I++ L +L N ++ + + Sbjct: 1152 QEQNIQLECLKQREQDLLNQIQQQNDQ 1178 Score = 83.4 bits (197), Expect = 5e-14 Identities = 165/861 (19%), Positives = 360/861 (41%), Gaps = 77/861 (8%) Query: 151 IKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXX 210 I+EKDN + L K + +L+ + E+D I K Sbjct: 771 IQEKDNQIGQLHTKRE-------ELKTMVQERDNQINHLRKEYITVQGRLSKLESENFDI 823 Query: 211 XEDTKQQMTKMQENFIAMEAEWKD---EKQRLLKDIESKDVRISSLEEANKLLEAARFEI 267 K+ + +Q + E +WK+ E R +++I + ++ +E K L ++ Sbjct: 824 NRKYKELQSLIQSKTLECE-DWKNKFIETDRKIENIPQLQIELNRNQETIKDLNQRIEQL 882 Query: 268 SLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKK 327 E+S + + + + I E+K +I+E ++ + + K Sbjct: 883 INENSGFKLRIGEKFGVENRINEKEREI-ENMITKINEQKKQIQE-FQAKVVELQNIEKS 940 Query: 328 IELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASK-----M 382 E+L + N L+ + + + +++ + ++ IS N K + Sbjct: 941 KEILFKQYKLFCEENNSLKQDIQSQLDKIQSLENQVQENIQDISLYQNENMQIKKEILQL 1000 Query: 383 KSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXX 442 K SQL + + +KK ++E KL + L ++L + +S+ Sbjct: 1001 KLENSQLQASLQDAVQEKKDLQSENEKLNETVNQLKQNLSN---TLSDTKERAQKVSYLT 1057 Query: 443 XGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKV-QEQLKQELNDEIKDVNVKDL 501 L +L+ +++Q +E L E N + ++ Q++L E +EI +K Sbjct: 1058 HENQNLANELK-KNKQELERVRL-------EKNNILYEINQQKLSVENYNEI----IKKF 1105 Query: 502 IEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLT 561 +K E + QL E D K+ V+ +KL +Q + + ++ + N ++ L Sbjct: 1106 EDKESKQIEDMKQLEREFDKKQKD---VQQLNKLLSEQESRLQNQIIQIQEQNIQLECLK 1162 Query: 562 EELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLES 621 + L ++ ++ N Q + G + ++ +KM +M N E Sbjct: 1163 QREQDLLNQI-----QQQNDQFAI----EGINLRMEINEKMSQMLN-----------AEK 1202 Query: 622 QKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSV-HLEEQIDALSASKKELAL 680 +KF+ Q+++I +KY++ +D++ ++Q + ++ K + +EE L+ +E+ Sbjct: 1203 EKFN--QQINIANKKYEQKDDEINQLTQKYNQEITENDKLIKKVEEYQQKLNEQFREMTD 1260 Query: 681 VIENLK-LDKE---QLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAE-KISEL 735 + L+ L KE Q++ IK E +++ NK++ ++ + E + K Sbjct: 1261 TKQKLESLQKEYQQQIHKIIKTNEQNQKKDQNKIEEISEQLRAAIQEKETIEQRLKSKRE 1320 Query: 736 LAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICR-LEESIAVMEDRRYS 794 A+I E+ K+ I ++ + NI+ E +Y I ++ I + Sbjct: 1321 DAQIWEEKYKKLLQAKEIQQYFDYQN-QLTNIKEESEQYNQMILNAYQQQIEEKNNEIKC 1379 Query: 795 LERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRV-VEKQLLEIEHENK-ELQ 852 LE + L LQ+ +E Q+ E +L + + +E Q +EI K +L Sbjct: 1380 LEEENQSLQQQLQKMVLLQNETYSQQSEKCKKLQEEISQREIQIETQTIEINQLKKYKLD 1439 Query: 853 KKNQILLEENQNLQI--SLSDMQQHYNALVEKANR--TDLAESESTKYQTQLRDLESNLK 908 ++++ + Q +I L +Q+ Y+ L EK N+ L + +++Q Q++D +K Sbjct: 1440 QESEKYQWQMQKSKIENQLEVLQKQYSEL-EKFNQGLNSLLQQRQSEFQ-QIQDDYERVK 1497 Query: 909 RITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQL-QEY 967 + +HQ +I Q + +IE +++ N +++S +D + + + + ++ + + +Q + + Sbjct: 1498 KENRDHQRIIKQMEIQIESEQLQ-NKRLQSQKKDDENIKQNLIERLKSLEEDSSQQNKRF 1556 Query: 968 KNNIENLNMNVEELNKMNLEL 988 +++ +N + N EL Sbjct: 1557 VESLQQINGLKDSFKTKNNEL 1577 Score = 48.4 bits (110), Expect = 0.002 Identities = 107/580 (18%), Positives = 233/580 (40%), Gaps = 62/580 (10%) Query: 215 KQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKL 274 K+ + E + K L D + + ++S L N+ ++ E K Sbjct: 1018 KKDLQSENEKLNETVNQLKQNLSNTLSDTKERAQKVSYLTHENQ-------NLANELKKN 1070 Query: 275 AQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELT----KKIEL 330 QELE+ K S+E E + E+K S +I +M +L KK + Sbjct: 1071 KQELERVRLEKNNILYEINQ-QKLSVENYNEIIKKFEDKESKQIEDMKQLEREFDKKQKD 1129 Query: 331 LEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNT-----ASKMKSP 385 ++ LN + + L+N++ + ++ + ++ L+++ +N ++ Sbjct: 1130 VQQLNKLLSEQESRLQNQIIQIQEQNIQLECLKQREQDLLNQIQQQNDQFAIEGINLRME 1189 Query: 386 WSQLSSETLNQDTDKKINKNEIA---------KLEMVIQSLNKDLVDKEYVISE-KDTXX 435 ++ S+ LN + +K + IA ++ + Q N+++ + + +I + ++ Sbjct: 1190 INEKMSQMLNAEKEKFNQQINIANKKYEQKDDEINQLTQKYNQEITENDKLIKKVEEYQQ 1249 Query: 436 XXXXXXXXGKDTL--IAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLK------- 486 DT + LQ E+QQ + + +D N+I ++ EQL+ Sbjct: 1250 KLNEQFREMTDTKQKLESLQKEYQQQIHKIIKTNEQNQKKDQNKIEEISEQLRAAIQEKE 1309 Query: 487 ---QELNDEIKDVNV-KDLIEKLKSAEE---------QITQLNDEIDAANKNMIKVKSNH 533 Q L + +D + ++ +KL A+E Q+T + +E + N+ ++ Sbjct: 1310 TIEQRLKSKREDAQIWEEKYKKLLQAKEIQQYFDYQNQLTNIKEESEQYNQMILNAYQQQ 1369 Query: 534 KLKLKQMQKTID--NFSKVSDSNKEIVRLTEELHHLSQKVAELEEE--KGNLQLHLVDYD 589 + K ++ N S K ++ E S+K +L+EE + +Q+ + Sbjct: 1370 IEEKNNEIKCLEEENQSLQQQLQKMVLLQNETYSQQSEKCKKLQEEISQREIQIETQTIE 1429 Query: 590 SGRMI------ESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELH-ILQQKYDEVED 642 ++ ES+ Y+ ++ + E +L+ + S+ Q L+ +LQQ+ E + Sbjct: 1430 INQLKKYKLDQESEKYQWQMQKSKI-ENQLEVLQKQYSELEKFNQGLNSLLQQRQSEFQQ 1488 Query: 643 KLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLEND 702 D +++ + + +E QI++ K L ++ + K+ L +K LE D Sbjct: 1489 IQDDYERVKKENRDHQRIIKQMEIQIESEQLQNKRLQSQKKDDENIKQNLIERLKSLEED 1548 Query: 703 KEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHE 742 + +Q+ L D K +++ L+K N + Sbjct: 1549 SSQQNKRFVESLQQINGLKDSF-KTKNNELTNFLSKTNKQ 1587 Score = 45.2 bits (102), Expect = 0.015 Identities = 75/381 (19%), Positives = 161/381 (42%), Gaps = 18/381 (4%) Query: 176 QEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDE 235 ++K +E +Q+ + N+ T E ++ MT ++ +++ E++ + Sbjct: 1217 EQKDDEINQLTQKYNQEITENDKLIKKVEEYQQKLNEQFRE-MTDTKQKLESLQKEYQQQ 1275 Query: 236 KQRLLKDIESKDVRISS-LEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXX 294 +++K E + + +EE ++ L AA E +L + E Sbjct: 1276 IHKIIKTNEQNQKKDQNKIEEISEQLRAAIQEKETIEQRLKSKREDAQIWEEKYKKLLQA 1335 Query: 295 LAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIR---QTNKELENKLAT 351 Q + T I+E+ E N L + +E N +I+ + N+ L+ +L Sbjct: 1336 KEIQQYFDYQNQLTNIKEES--EQYNQMILNAYQQQIEEKNNEIKCLEEENQSLQQQLQK 1393 Query: 352 MGT-ESKAVSSPSKKGSPLISRKSGRNTASKMKS-PWSQLSSETLNQDTDKKINKNEIAK 409 M +++ S S+K L S R + ++ +QL L+Q+++K + + +K Sbjct: 1394 MVLLQNETYSQQSEKCKKLQEEISQREIQIETQTIEINQLKKYKLDQESEKYQWQMQKSK 1453 Query: 410 LEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVG 469 +E ++ L K +Y SE + + + Q+Q ++++ ++ + H Sbjct: 1454 IENQLEVLQK-----QY--SELEKFNQGLNSLLQQRQSEFQQIQDDYER-VKKENRDHQR 1505 Query: 470 TNTEDVNEIAKVQEQLKQELNDEIKDVNVK-DLIEKLKSAEEQITQLNDEIDAANKNMIK 528 + +I Q Q K+ + + D N+K +LIE+LKS EE +Q N + + + Sbjct: 1506 IIKQMEIQIESEQLQNKRLQSQKKDDENIKQNLIERLKSLEEDSSQQNKRFVESLQQING 1565 Query: 529 VKSNHKLKLKQMQKTIDNFSK 549 +K + K K ++ + +K Sbjct: 1566 LKDSFKTKNNELTNFLSKTNK 1586 >UniRef50_A0CUE6 Cluster: Chromosome undetermined scaffold_28, whole genome shotgun sequence; n=1; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_28, whole genome shotgun sequence - Paramecium tetraurelia Length = 1479 Score = 134 bits (323), Expect = 3e-29 Identities = 239/1252 (19%), Positives = 552/1252 (44%), Gaps = 129/1252 (10%) Query: 445 KDTLIAQL-QLEHQQHMEGPSLIHVGTNTEDVNEIAKVQ-EQLKQE------LNDEIKDV 496 K+TL + L +L++ ++ + L+ + + + + E Q LK+E LN+ + ++ Sbjct: 99 KNTLESNLNELKYHENAQKLELLELESKCQILQEETSTQTNNLKEENIRLQGLNETL-EI 157 Query: 497 NVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSD--SN 554 +KD + +QI Q+N++ + N+ + + N L + + + + ++ + S Sbjct: 158 QIKDQKSQNIDQLKQIEQINEKYNLINEQFTQQQKNLSLFEQTINEQRNQIQEIDNGQSK 217 Query: 555 KEIVRLT---EELHHL-SQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAE 610 +E+ L E+L L +Q + E E++ + MIE+ K + + E Sbjct: 218 QELNILAIQHEQLKLLHNQLIIEKEQQLSYINKQCQQEIDVLMIEN---KDLSFQNHKLE 274 Query: 611 TRLKAISLLESQKFD------LVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSV-H 663 ++K + L+ +Q D +QE + Q + E + L ++ ++ I+S+ Sbjct: 275 QKIKKLQLINNQLIDQQDINLKIQENELKQLYFGEQQKNLE--LDIKINETYQRIESLQQ 332 Query: 664 LEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKL----QNYIQENMD 719 L EQ++ ++ V E +D ++ + N +E + KL + +Q+ D Sbjct: 333 LNEQLEQKIKDLEQQLNVQEQQNVDLHKVNNELVQNNNIQESNLQKLKIINEIQLQKITD 392 Query: 720 LTDKLEKMSAEKISELLA--KINHEEQSKIQ-TQFGIDAKIQERDLYIENIESEL-SKYK 775 L + ++++ +K+++ ++ K+ ++ K++ T + K++++ + +++ S+L +KY Sbjct: 393 LANG-QELNLQKLNDPISQLKLLPQKFQKLEITLLRLLPKLRQKIIQQQDLISQLINKYS 451 Query: 776 SRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDR 835 + I L + + +D+ L + Q E + + ++ + +++L +D + Sbjct: 452 NNIDDLNQQLLKQQDKSNQLYDQVLQNQELNSELKNLNDKLESEKQQNISKLEKQIDLNE 511 Query: 836 VVEKQLLEIEHENKELQKKNQILLEENQNLQISL-SDMQQHYNALVEKANRTDLAESEST 894 + Q + + +E + + + L ++ Q+ Q S++QQ N ++ E T Sbjct: 512 QIGAQNAFLSQQKQEFENELKQLQQDYQDQQSKWNSEIQQKIQENSTIKNENEIFNQELT 571 Query: 895 KYQTQLRDLESNLKRI----THEHQTLIVQKKKEIEDLEIEFNTQ------IESAIRDKK 944 K Q++ L +K+ E + LI+++++EI+ +E++ + Q ++ ++K+ Sbjct: 572 KKNEQIQILSKEIKQFQINSQCEQEELILKRQQEIKIIEVKISEQQNNFLNNQNQYQEKQ 631 Query: 945 VL-----NEKYEKNIEYVTQLEAQL----QEYKNNIENLNMNVEELNKMNLELIDKHVQK 995 +L K+ K E L +L E K I+ + LN+ N +++ +++ Sbjct: 632 ILRLNFIKNKFNKEQEVTKLLNIELNSIQMEMKQLIDRHLVQSSSLNQEN-QILQDNLKI 690 Query: 996 QQTQSPDYTEQYI---NEINKLNALLKQKDEEIIA---LNQKINNAQV----SYMSMVSD 1045 ++ D Q + +I KLN + QKD+EI + +N +N Q+ + + ++ Sbjct: 691 EREAKEDLNSQIVQIKKQIVKLNNTINQKDQEIESFRKINDALNERQIIDKQALSNDLNS 750 Query: 1046 YESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKEL----KETKL- 1100 + +QF +++ +++++ +++ LL Q E+Q L ++ DQ+KE+ +E ++ Sbjct: 751 IQESNSQFKQQIQQLQDQINNINEILLAKDQ---EIQTLKQKLQDQVKEINLKTQEYEIK 807 Query: 1101 TFEMNIPKTEGM-IISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQE 1159 E+N K EG+ + + + +N++ L+ Q E+ +E Sbjct: 808 NVELNNIKEEGLKKLKCKDDEILQLQDNLEQQKIKYESQSLVLQ-QNLEQLQINLKKKEE 866 Query: 1160 QSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLL----S 1215 + +++N+ +E +L+ N L G + ++ +N +E + + D+ + + Sbjct: 867 EISRINSANEELKASNKELQDQNKILQGQSLQQEQNLNLRIVNIEAIIEDKDDEIQLKQN 926 Query: 1216 TVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSV 1275 + +L+ SI++ +++ + + KQ R Q EL+ Q ++E+L Sbjct: 927 ELNDLKESINTYLERFSCDQQIIQKQQFEIR--ILQNQIEELKNQ-----GEFEKLEFQQ 979 Query: 1276 QSSTQEETNKIVTME-QVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAF 1334 Q +++ + I E ++TSL N +++KE+ L++ DVI + +S+ ++ F Sbjct: 980 QLQIKKQKSNIGQFEDEITSLNNVIEEKEKPTDQLKQNMNDVITN-KFNQSQYVNQIKEF 1038 Query: 1335 --XXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILN--------INEENAQLKKSSXXX 1384 D+++ Q + +Q ++N + EEN ++K Sbjct: 1039 DDFDENNKNSVNEQQQLIDIKSARQRWINETDQELVNEERVLFQKLREENNIIRKQLADQ 1098 Query: 1385 XXXXXXXXXRVNDAEAKVLELTHQLELK-----------------DSEIYQKTHEYTITL 1427 R+ D E +L L +LE + + +I Q + + I Sbjct: 1099 EKELIINNQRIYDHEETILNLQQELEARKYNNNSPRPLDKEINQDEGQIDQDSEQQQIQQ 1158 Query: 1428 TQRNDEFENVR-QQLVEYEKRIEDL---TYEKESELAILRLKMHENANHYETMQKESEIE 1483 Q + NV+ QQ+++ + E L Y+ + EL + K++++ + +Q E + Sbjct: 1159 KQYQQKVSNVQPQQILKLREENEILKRNLYDLQLELELNNQKLNDHEQTIQNLQTELYEK 1218 Query: 1484 RVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNL 1543 + K N + VS Q++ +K +E++ +E+Q+ V ND Sbjct: 1219 KEKTENFENKLMDNQVS---QLSNRSKLSQEQIRFDQLPDIGVEDQD---VADNDSFEQE 1272 Query: 1544 QNMVRASSSKI-QKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDLAMY 1594 +N+ + + Q+ ++ Q +QL NK L D + R +Y Sbjct: 1273 ENIFQQRQLNLKQQELTNTIKELQEEIKQL-KEQNKSLQDFINRGSAPSPIY 1323 Score = 133 bits (321), Expect = 4e-29 Identities = 255/1212 (21%), Positives = 512/1212 (42%), Gaps = 134/1212 (11%) Query: 458 QHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQL-- 515 QH E L+H E +++ + +Q +QE+ ++ + KDL + E++I +L Sbjct: 226 QH-EQLKLLHNQLIIEKEQQLSYINKQCQQEI--DVLMIENKDLSFQNHKLEQKIKKLQL 282 Query: 516 --NDEIDAANKNMIKVKSNH--KLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKV 571 N ID + N+ K++ N +L + QK ++ K++++ + I L + L QK+ Sbjct: 283 INNQLIDQQDINL-KIQENELKQLYFGEQQKNLELDIKINETYQRIESLQQLNEQLEQKI 341 Query: 572 AELEE-----EKGNLQLHLVDYD---SGRMIESDVYKKMI--EMENLAETRLKAISLLES 621 +LE+ E+ N+ LH V+ + + + ES++ K I E++ T L L Sbjct: 342 KDLEQQLNVQEQQNVDLHKVNNELVQNNNIQESNLQKLKIINEIQLQKITDLANGQELNL 401 Query: 622 QKF-DLVQELHILQQKYDEVEDKLADISQ------LQSDQVCSEIKSVH------LEEQI 668 QK D + +L +L QK+ ++E L + +Q + S++ + + L +Q+ Sbjct: 402 QKLNDPISQLKLLPQKFQKLEITLLRLLPKLRQKIIQQQDLISQLINKYSNNIDDLNQQL 461 Query: 669 DALSASKKELA-LVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKM 727 +L V++N +L+ E L LE++K+ ++KL+ I N + + + Sbjct: 462 LKQQDKSNQLYDQVLQNQELNSE-LKNLNDKLESEKQQNISKLEKQIDLNEQIGAQNAFL 520 Query: 728 SAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAV 787 S +K E ++ +Q Q +++IQ++ I++E + + + E I + Sbjct: 521 SQQK-QEFENELKQLQQDYQDQQSKWNSEIQQKIQENSTIKNENEIFNQELTKKNEQIQI 579 Query: 788 M--EDRRYSLERKADQLGSYLQEKQKA-YSEYTIQEDELVNRLAVLMDHDRVVEKQLLEI 844 + E +++ + + +Q L+ +Q+ E I E + N L + ++ EKQ+L + Sbjct: 580 LSKEIKQFQINSQCEQEELILKRQQEIKIIEVKISEQQ--NNF--LNNQNQYQEKQILRL 635 Query: 845 EHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLE 904 + K+ ++ + L I L+ +Q L+++ L +S S + Q+ L+ Sbjct: 636 NFIKNKFNKEQEV----TKLLNIELNSIQMEMKQLIDR----HLVQSSSLNQENQI--LQ 685 Query: 905 SNLKRITHEHQTL---IVQKKKEI---------EDLEIEFNTQIESAIRDKKV------- 945 NLK + L IVQ KK+I +D EIE +I A+ ++++ Sbjct: 686 DNLKIEREAKEDLNSQIVQIKKQIVKLNNTINQKDQEIESFRKINDALNERQIIDKQALS 745 Query: 946 --LNEKYEKNIEYVTQLEAQLQEYKNNI-ENLNMNVEELNKMNLELIDKHVQ-KQQTQSP 1001 LN E N ++ Q++ QLQ+ NNI E L +E+ + +L D+ + +TQ Sbjct: 746 NDLNSIQESNSQFKQQIQ-QLQDQINNINEILLAKDQEIQTLKQKLQDQVKEINLKTQEY 804 Query: 1002 DYTEQYINEINKLNAL-LKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENM 1060 + +N I + LK KD+EI+ L + ++ Y S + L Q L+ Sbjct: 805 EIKNVELNNIKEEGLKKLKCKDDEILQLQDNLEQQKIKYESQSLVLQQNLEQLQINLKKK 864 Query: 1061 EEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEP 1120 EEE+ R++ NEEL+ +E DQ K L+ L E N+ + I + IE Sbjct: 865 EEEISRINSA-------NEELKASNKELQDQNKILQGQSLQQEQNL-NLRIVNIEAIIED 916 Query: 1121 MSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAK---LNTELQECYTKIIQ 1177 D+ + + E F ++ ++Q+Q + L +++E + + Sbjct: 917 KDDE---IQLKQNELNDLKESINTY-LERFSCDQQIIQKQQFEIRILQNQIEELKNQ-GE 971 Query: 1178 LETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAE 1237 E L + + I Q + ++ LN + +L+ +++ + + F ++ Sbjct: 972 FEKLEFQQQLQIKKQKSNIGQFEDEITSLNNVIEEKEKPTDQLKQNMNDVITNK-FNQSQ 1030 Query: 1238 LWKQHLAQREAD-FQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIV--TMEQVTS 1294 Q + D K + QL +S ++ ++ E + E+ Sbjct: 1031 YVNQIKEFDDFDENNKNSVNEQQQLIDIKSARQRWINETDQELVNEERVLFQKLREENNI 1090 Query: 1295 LQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKV------AFXXXXXXXXXXXXXX 1348 ++ +L D+E+ L ++ D I L+ E+E K Sbjct: 1091 IRKQLADQEKELIINNQRIYDHEETILNLQQELEARKYNNNSPRPLDKEINQDEGQIDQD 1150 Query: 1349 XXDLRTENQSYKQ----MQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLE 1404 + + + Y+Q +Q Q IL + EEN LK++ ++ND E + Sbjct: 1151 SEQQQIQQKQYQQKVSNVQPQQILKLREENEILKRNLYDLQLELELNNQKLNDHEQTIQN 1210 Query: 1405 LTHQL------------ELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLT 1452 L +L +L D+++ Q ++ L+Q F+ + VE + ++ + Sbjct: 1211 LQTELYEKKEKTENFENKLMDNQVSQLSNR--SKLSQEQIRFDQLPDIGVEDQDVADNDS 1268 Query: 1453 YEKESEL---AILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELN 1509 +E+E + L LK E N + +Q+E +K ++E N + + ++ + + Sbjct: 1269 FEQEENIFQQRQLNLKQQELTNTIKELQEE-----IKQLKEQNKSLQDFINRGSAPSPIY 1323 Query: 1510 KALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRD 1569 E + K++++ E + + L +++ + SK Q F D + Sbjct: 1324 NR-ESDPNKSSKIAQETEKRRQD---LQNQLYEKDQTFSHNKSKSQVLFEFTQDEENQAG 1379 Query: 1570 EQLDNTMNKELL 1581 + L + KE L Sbjct: 1380 DDLAEDIKKERL 1391 Score = 83.0 bits (196), Expect = 6e-14 Identities = 146/846 (17%), Positives = 345/846 (40%), Gaps = 55/846 (6%) Query: 764 IENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDEL 823 + NI + +S + L+ + LE K L + E I+ L Sbjct: 92 LSNITQTKNTLESNLNELKYHENAQKLELLELESKCQILQEETSTQTNNLKEENIRLQGL 151 Query: 824 VNRLAV-LMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEK 882 L + + D QL +IE N++ N+ ++ +NL + +Q N Sbjct: 152 NETLEIQIKDQKSQNIDQLKQIEQINEKYNLINEQFTQQQKNLSL----FEQTIN----- 202 Query: 883 ANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRD 942 R + E ++ + + +L L +++ H LI++K++++ + + +I+ + + Sbjct: 203 EQRNQIQEIDNGQSKQELNILAIQHEQLKLLHNQLIIEKEQQLSYINKQCQQEIDVLMIE 262 Query: 943 KKVL---NEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQ 999 K L N K E+ I+ + + QL + +++N+ ++E L ++ + Sbjct: 263 NKDLSFQNHKLEQKIKKLQLINNQLIDQ----QDINLKIQENELKQLYFGEQQKNLELDI 318 Query: 1000 SPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLEN 1059 + T Q I + +LN L+QK ++ L Q++N + + + ++L Q E+ Sbjct: 319 KINETYQRIESLQQLNEQLEQKIKD---LEQQLNVQEQQNVDL-HKVNNELVQNNNIQES 374 Query: 1060 MEEEMQRVSK---QLLDSKQHNEELQILVREQDDQIKELK-------ETKLTFEMNIPKT 1109 ++++ +++ Q + + +EL + ++ +D I +LK + ++T +PK Sbjct: 375 NLQKLKIINEIQLQKITDLANGQELNL--QKLNDPISQLKLLPQKFQKLEITLLRLLPKL 432 Query: 1110 EGMIISS---TIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQER---SVLQEQSAK 1163 II + ++ +NN+D Q ++ +Q + S L+ + K Sbjct: 433 RQKIIQQQDLISQLINKYSNNIDDLNQQLLKQQDKSN-QLYDQVLQNQELNSELKNLNDK 491 Query: 1164 LNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTE-NDNLLSTVAELRS 1222 L +E Q+ +K+ + LN ++ + +Q + +++L+QL + D +E++ Sbjct: 492 LESEKQQNISKLEKQIDLNEQIGAQNAFLSQQKQEFENELKQLQQDYQDQQSKWNSEIQQ 551 Query: 1223 SISSAVDQRGFEIAELWKQHLAQREADFQKTEHELR-VQLSAFESKYEQLLDSVQSSTQE 1281 I + E++ Q L ++ Q E++ Q+++ + E +L Q Sbjct: 552 KIQENSTIKNEN--EIFNQELTKKNEQIQILSKEIKQFQINSQCEQEELILKRQQEIKII 609 Query: 1282 ETNKIVTMEQVTSLQNKLQDKE-EHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXX 1340 E + QN+ Q+K+ L ++ K+ ++L E+ ++ Sbjct: 610 EVKISEQQNNFLNNQNQYQEKQILRLNFIKNKFNKEQEVTKLLNIELNSIQMEMKQLIDR 669 Query: 1341 XXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEA 1400 + + + K ++ ++ ++N + Q+KK + ++ Sbjct: 670 HLVQSSSLNQENQILQDNLK-IEREAKEDLNSQIVQIKKQIVKLNNTINQKDQEI-ESFR 727 Query: 1401 KVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELA 1460 K+ + ++ ++ D + ++ + N +F+ QQL + I ++ K+ E+ Sbjct: 728 KINDALNERQIIDKQALSNDLN---SIQESNSQFKQQIQQLQDQINNINEILLAKDQEIQ 784 Query: 1461 ILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTN 1520 L+ K+ + +E EI+ V+L + + + ++ +L LE++ K Sbjct: 785 TLKQKLQDQVKEINLKTQEYEIKNVELNNIKEEGLKKLKCKDDEILQLQDNLEQQKIKYE 844 Query: 1521 E----MQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTM 1576 +Q LE +I + +EI+ + N K + + QG+ Q + + Sbjct: 845 SQSLVLQQNLEQLQINLKKKEEEISRI-NSANEELKASNKELQDQNKILQGQSLQQEQNL 903 Query: 1577 NKELLD 1582 N +++ Sbjct: 904 NLRIVN 909 Score = 56.0 bits (129), Expect = 8e-06 Identities = 141/742 (19%), Positives = 308/742 (41%), Gaps = 62/742 (8%) Query: 147 LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXX 206 L + +K + A L ++ ++ I+ L IN+KDQ IE+ K Sbjct: 684 LQDNLKIEREAKEDLNSQIVQIKKQIVKLNNTINQKDQEIESFRKINDALNERQIIDKQA 743 Query: 207 XXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLL-KDIESKDVRISSLEEANKL-LEAAR 264 ++ ++ ++ ++ + + + LL KD E + ++ ++ ++ L+ Sbjct: 744 LSNDLNSIQESNSQFKQQIQQLQDQINNINEILLAKDQEIQTLKQKLQDQVKEINLKTQE 803 Query: 265 FEI-SLEHSKLAQE-LEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMT 322 +EI ++E + + +E L++ L +Q I+ + + L+I N+ Sbjct: 804 YEIKNVELNNIKEEGLKKLKCKDDEILQLQDNLEQQKIKYESQSLVLQQNLEQLQI-NLK 862 Query: 323 ELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKM 382 + ++I + N +++ +NKEL+++ + +S ++ L R + Sbjct: 863 KKEEEISRINSANEELKASNKELQDQNKILQGQSL------QQEQNLNLRIVNIEAIIED 916 Query: 383 KSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXX 442 K QL LN D + IN + + Q + K + + ++ + Sbjct: 917 KDDEIQLKQNELN-DLKESIN-TYLERFSCDQQIIQKQQFEIRILQNQIEELKNQGEFE- 973 Query: 443 XGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKD-VNVKDL 501 K QLQ++ Q+ G + + + E K +QLKQ +ND I + N Sbjct: 974 --KLEFQQQLQIKKQKSNIGQFEDEITSLNNVIEEKEKPTDQLKQNMNDVITNKFNQSQY 1031 Query: 502 IEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLT 561 + ++K D+ D NKN + N + +L ++ + ++++++E+V Sbjct: 1032 VNQIKEF--------DDFDENNKNSV----NEQQQLIDIKSARQRW--INETDQELV--- 1074 Query: 562 EELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESD-VYKKMIEMENLAETRLKAISLLE 620 E L QK L EE ++ L D + +I + +Y + NL + L+A Sbjct: 1075 NEERVLFQK---LREENNIIRKQLADQEKELIINNQRIYDHEETILNL-QQELEARKYNN 1130 Query: 621 SQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELAL 680 + L +E++ + + D+ + + I Q Q Q S ++ + + + K+ L Sbjct: 1131 NSPRPLDKEINQDEGQIDQ-DSEQQQIQQKQYQQKVSNVQPQQILKLREENEILKRNLYD 1189 Query: 681 VIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLE-KMSAEKISELLAKI 739 + L+L+ ++L ND E + LQ + E + T+ E K+ ++S+L Sbjct: 1190 LQLELELNNQKL--------NDHEQTIQNLQTELYEKKEKTENFENKLMDNQVSQL---S 1238 Query: 740 NHEEQSKIQTQFG--IDAKIQERDLY-IENIESELSKYKSRICRLEE-----SIAVMEDR 791 N + S+ Q +F D ++++D+ ++ E E + ++ R L++ +I +++ Sbjct: 1239 NRSKLSQEQIRFDQLPDIGVEDQDVADNDSFEQEENIFQQRQLNLKQQELTNTIKELQEE 1298 Query: 792 RYSLERKADQLGSYLQEKQKAYSEYTIQED-ELVNRLAVLMDHDRV-VEKQLLEIEHENK 849 L+ + L ++ Y + D +++A + R ++ QL E + Sbjct: 1299 IKQLKEQNKSLQDFINRGSAPSPIYNRESDPNKSSKIAQETEKRRQDLQNQLYEKDQTFS 1358 Query: 850 ELQKKNQILLEENQNLQISLSD 871 + K+Q+L E Q+ + D Sbjct: 1359 HNKSKSQVLFEFTQDEENQAGD 1380 >UniRef50_UPI00006CB2D6 Cluster: Viral A-type inclusion protein repeat containing protein; n=1; Tetrahymena thermophila SB210|Rep: Viral A-type inclusion protein repeat containing protein - Tetrahymena thermophila SB210 Length = 1671 Score = 133 bits (321), Expect = 4e-29 Identities = 175/900 (19%), Positives = 395/900 (43%), Gaps = 46/900 (5%) Query: 451 QLQLEHQQHMEGPSLIHVG-TNTEDVNEIAKVQ---EQLKQELNDEIKDVNVKDLIEKLK 506 Q+ L + +H + P I + N+E N+I K++ E L + D+ ++ + L +K Sbjct: 584 QMNLLNNKHKKDPHQIELEYQNSELRNQIMKLKNEIEMLNLKRKDDNSNIQIDLLTKKNT 643 Query: 507 SAEEQITQLNDEIDAANKN--MIKVKSNHKLKLKQMQKTIDNFSKV-SDSNKEIVRLTEE 563 ++QI +L +++ N + +K S+ + +L + K N NKE Sbjct: 644 LLQDQINKLEQQLNQVNNSNEYVKAISSLQKQLDERDKAYQNLHLYYQKDNKENYISAAN 703 Query: 564 LHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDV---YKKMIEMENLAETRLKAISLLE 620 + + V + EE K +L+ + +++ + +++ +N + +L+ + Sbjct: 704 QNDANNAVNKTEEAKIIEKLNTRVANLTVLLQQSAKISFNQILRKQNDKQQKLQDKIFQQ 763 Query: 621 SQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELAL 680 QK QE ++K + I Q++ K + L +Q K E+ L Sbjct: 764 EQKLIASQE-ESQKEKNKYISFHEEKIKQIEQRYYSENKKVLSLLDQTK--EQHKDEINL 820 Query: 681 VIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKIN 740 + + +K + + K L+N +E I +L + I + ++L K S +++ L N Sbjct: 821 LNQKIKSQECDMIEKTKQLKNAQEQIA-RLNSQISQKQKEYEELNKKS-QQVENRLKTDN 878 Query: 741 HEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKAD 800 ++ +++Q+Q D++ ++ L +E++L+ +S L+ + + L+ K + Sbjct: 879 AKQVTELQSQLQKDSEKYKKRL--AQLETDLANKQSV---LQNQTKDFNNVKRDLDLKHE 933 Query: 801 QLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKN---QI 857 + E Q+ +E + +++N + + D+ VEK LEI+ NK+ Q N Q Sbjct: 934 EYEKVQYELQQVQNERDRLKKDVMNLKNRIENLDQTVEKNRLEIQQLNKQNQALNNEKQS 993 Query: 858 LLEENQNLQISLSDMQQHYNALVEKANRTDLAESES-TKYQTQLRDLESNLKRITHEHQT 916 + E+ Q + + D+Q+ +++ + S ++ ++Q DL+ I + ++ Sbjct: 994 ISEDIQKDKQQVQDLQKRLTQILDSVKSLESERSRLLSQIESQKLDLDKKKIEIDNLNKQ 1053 Query: 917 LIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEK---YEKNIE-YVTQ---LEAQLQEYKN 969 + Q + + LE +Q+ ++ LNE+ Y+ I+ + T+ LEA +Q Sbjct: 1054 VYEQSNERAQQLEKLMESQMNEKLKIS-ALNEQVQIYKIEIDQFKTKMQILEADIQARDE 1112 Query: 970 NIENLNMNVEELNKMNLELIDKHVQK---QQTQSPDYTEQYINEINKLNALLKQKDEEII 1026 I+ LN N+E K+ ++ DK ++ +Q++ EQ I LNA ++Q E Sbjct: 1113 KIKILNKNIET-QKITIDENDKKIESLVSEQSKVIAENEQKNQLITNLNAAIEQALIECE 1171 Query: 1027 ALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVR 1086 + N+ +V +Y+ +L + ++ + + ++ ++ N EL + Sbjct: 1172 IQQKNANSKKVELEEKQEEYKHELERLQNEINELGRNLATCKERERETNNKNVELIQQIE 1231 Query: 1087 EQDDQI--KELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKV 1144 E + + KE + ++ EMN+ K +++ ++ D D L Sbjct: 1232 EANHNLNQKEQELNQIVEEMNLNKNHINSNEMSLKQLNLDLKERDDYVSNLQDEVKNL-T 1290 Query: 1145 QEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLE 1204 Q+ E+ ++ Q++ LN+++ + + +E N EL + + L+S L+ Sbjct: 1291 QQLEDLQRQDLQNQQEIENLNSQINKLKNNLNSMEDKNQELQSKTNNLLQNVIDLQSSLQ 1350 Query: 1205 QLNTENDNLLSTVAELRSSISSAVDQRGFEIA---ELWKQHLAQREADFQKTEHELRVQL 1261 QL E + + L+ S+ +++ I E K++ + + H + Sbjct: 1351 QLRVEKELIEQNNQLLQESLQKEKEEKEIAIRCQDEQEKEYEKLKNSTICIDAHTQALDK 1410 Query: 1262 SAFESKYEQL-LDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQI 1320 ++ ++L ++ Q ++ +++T E T++Q++ + + H + +QE Y I+++ Sbjct: 1411 LEIKNDQQKLEIEKQQEQLEQFAQQLITAE--TTIQSQKKQLDGH-KIIQENYLKTISEL 1467 Score = 121 bits (292), Expect = 1e-25 Identities = 176/895 (19%), Positives = 393/895 (43%), Gaps = 66/895 (7%) Query: 327 KIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISR-KSGRNTASKMKSP 385 +I+LL N ++ +LE +L + ++ V + S L R K+ +N + Sbjct: 634 QIDLLTKKNTLLQDQINKLEQQLNQVNNSNEYVKAISSLQKQLDERDKAYQNLHLYYQKD 693 Query: 386 WSQLSSETLNQ-DTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXG 444 + NQ D + +NK E AK +I+ LN + + V+ ++ Sbjct: 694 NKENYISAANQNDANNAVNKTEEAK---IIEKLNTRVANLT-VLLQQSAKISFNQILRKQ 749 Query: 445 KDTLIAQLQLEHQQHMEGPSLIHVGTNTE-DVNEIAKVQEQLKQELNDEIKDVNVKDLIE 503 D Q +L+ + + LI ++ + N+ E+ +++ N K ++ Sbjct: 750 NDK---QQKLQDKIFQQEQKLIASQEESQKEKNKYISFHEEKIKQIEQRYYSEN-KKVLS 805 Query: 504 KLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEE 563 L +EQ DEI+ N+ + + + K KQ++ + +++ N +I + +E Sbjct: 806 LLDQTKEQH---KDEINLLNQKIKSQECDMIEKTKQLKNAQEQIARL---NSQISQKQKE 859 Query: 564 LHHLSQKVAELEEE-KGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQ 622 L++K ++E K + + + S +S+ YKK + L S+L++Q Sbjct: 860 YEELNKKSQQVENRLKTDNAKQVTELQSQLQKDSEKYKK--RLAQLETDLANKQSVLQNQ 917 Query: 623 KFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVI 682 D L K++E E ++ Q+Q+++ + ++L+ +I+ L + ++ L I Sbjct: 918 TKDFNNVKRDLDLKHEEYEKVQYELQQVQNERDRLKKDVMNLKNRIENLDQTVEKNRLEI 977 Query: 683 ENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHE 742 + L + L + + D + ++Q+ + + D ++ + +E+ S LL++I + Sbjct: 978 QQLNKQNQALNNEKQSISEDIQKDKQQVQDLQKRLTQILDSVKSLESER-SRLLSQIESQ 1036 Query: 743 EQSKIQTQFGID-------AKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSL 795 + + + ID + ER +E + K +I L E + + + Sbjct: 1037 KLDLDKKKIEIDNLNKQVYEQSNERAQQLEKLMESQMNEKLKISALNEQVQIYKIEIDQF 1096 Query: 796 ERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKN 855 + K L + +Q + + + I + + + ++D+ +E + E E ++KN Sbjct: 1097 KTKMQILEADIQARDE---KIKILNKNIETQKITIDENDKKIESLVSEQSKVIAENEQKN 1153 Query: 856 QILLEENQNLQISLSDMQ-QHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEH 914 Q++ N ++ +L + + Q NA + + +L E + +Y+ +L L++ + + Sbjct: 1154 QLITNLNAAIEQALIECEIQQKNA---NSKKVELEEKQE-EYKHELERLQNEINELGRNL 1209 Query: 915 QTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENL 974 T ++++E + +E QIE A + LN+K ++ + Q+ ++ KN+I + Sbjct: 1210 ATC-KERERETNNKNVELIQQIEEANHN---LNQKEQE----LNQIVEEMNLNKNHINSN 1261 Query: 975 NMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINN 1034 M++++LN ++L+ D +V Q + + T+Q + ++ + + Q +EI LN +IN Sbjct: 1262 EMSLKQLN-LDLKERDDYVSNLQDEVKNLTQQ-LEDLQRQDL---QNQQEIENLNSQINK 1316 Query: 1035 AQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKE 1094 + + SM D +L T L ++Q +QL K+ E+ L++E + KE Sbjct: 1317 LKNNLNSM-EDKNQELQSKTNNLLQNVIDLQSSLQQLRVEKELIEQNNQLLQESLQKEKE 1375 Query: 1095 LKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQER 1154 KE + + K + +STI DA+ L+++ +++ ++ Sbjct: 1376 EKEIAIRCQDEQEKEYEKLKNSTI---CIDAHT---------QALDKLEIKNDQQKLE-- 1421 Query: 1155 SVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTE 1209 +++Q +L Q+ T +++ +L GH ++ + + + +LN E Sbjct: 1422 --IEKQQEQLEQFAQQLITAETTIQSQKKQLDGHKIIQENYLKTISELSSKLNVE 1474 Score = 116 bits (279), Expect = 5e-24 Identities = 214/1078 (19%), Positives = 463/1078 (42%), Gaps = 92/1078 (8%) Query: 483 EQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSN-HKLKLKQMQ 541 E+L + N+ + DL ++L+ E + Q D + + + +N HK Q++ Sbjct: 541 EKLPKIENEHDEKDKYFDLFKQLELPEYGLKQEEMIADLKKELQMNLLNNKHKKDPHQIE 600 Query: 542 KTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYK- 600 N S+ +I++L E+ L+ K +++ N+Q+ L+ +++ + K Sbjct: 601 LEYQN----SELRNQIMKLKNEIEMLNLK---RKDDNSNIQIDLLT-KKNTLLQDQINKL 652 Query: 601 -KMIEMENLAETRLKAISLLESQ---KFDLVQELHILQQKYDEVEDKLADISQLQSDQVC 656 + + N + +KAIS L+ Q + Q LH+ QK D E+ ++ +Q ++ Sbjct: 653 EQQLNQVNNSNEYVKAISSLQKQLDERDKAYQNLHLYYQK-DNKENYISAANQNDANNAV 711 Query: 657 SEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYI-Q 715 ++ + + E+++ A+ L+ ++ K+ Q+ +NDK+ KLQ+ I Q Sbjct: 712 NKTEEAKIIEKLNTRVANLT--VLLQQSAKISFNQILRK----QNDKQQ---KLQDKIFQ 762 Query: 716 ENMDLTDKLEKMSAEK---ISELLAKINHEEQSKIQTQFGIDAKI-QERDLYIENIESEL 771 + L E+ EK IS KI EQ + + + Q ++ + + I Sbjct: 763 QEQKLIASQEESQKEKNKYISFHEEKIKQIEQRYYSENKKVLSLLDQTKEQHKDEINLLN 822 Query: 772 SKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLM 831 K KS+ C + E +++ + + R L S + +KQK Y E + ++ NRL Sbjct: 823 QKIKSQECDMIEKTKQLKNAQEQIAR----LNSQISQKQKEYEELNKKSQQVENRLKT-- 876 Query: 832 DHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAES 891 D+ + V + +++ ++++ +K+ L + N Q L + + +N + DL Sbjct: 877 DNAKQVTELQSQLQKDSEKYKKRLAQLETDLANKQSVLQNQTKDFNNVKRDL---DLKHE 933 Query: 892 ESTKYQTQLRDLESNLKRITHEHQTL---IVQKKKEIED--LEIE-FNTQIESAIRDKKV 945 E K Q +L+ +++ R+ + L I + +E LEI+ N Q ++ +K+ Sbjct: 934 EYEKVQYELQQVQNERDRLKKDVMNLKNRIENLDQTVEKNRLEIQQLNKQNQALNNEKQS 993 Query: 946 LNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEEL-NKMNLELIDKHVQKQQTQSPDYT 1004 ++E +K+ + V L+ +L + +++++L L +++ + +D + K++ + + Sbjct: 994 ISEDIQKDKQQVQDLQKRLTQILDSVKSLESERSRLLSQIESQKLD--LDKKKIEIDNLN 1051 Query: 1005 EQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEM 1064 +Q + N+ L++ E +N+K+ + ++ V Y+ ++ QF TK++ +E ++ Sbjct: 1052 KQVYEQSNERAQQLEKLMES--QMNEKLKISALN--EQVQIYKIEIDQFKTKMQILEADI 1107 Query: 1065 QRVSKQLLDSKQHNEELQILVREQDDQIKEL--KETKLTFEMNIPKTEGMIISSTIEPMS 1122 Q +++ ++ E +I + E D +I+ L +++K+ E N K + +I++ + Sbjct: 1108 QARDEKIKILNKNIETQKITIDENDKKIESLVSEQSKVIAE-NEQKNQ--LITNLNAAIE 1164 Query: 1123 DDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLN 1182 + L+ +++EE+ E LQ + +L L C + + ET N Sbjct: 1165 QALIECEIQQKNANSKKVELE-EKQEEYKHELERLQNEINELGRNLATCKER--ERETNN 1221 Query: 1183 TELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQH 1242 N E I Q++ LN + L V E+ + + ++ + +L Sbjct: 1222 K--------NVELIQQIEEANHNLNQKEQELNQIVEEMNLN-KNHINSNEMSLKQL-NLD 1271 Query: 1243 LAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDK 1302 L +R+ + E++ E Q L + Q E N Q+ L+N L Sbjct: 1272 LKERDDYVSNLQDEVKNLTQQLEDLQRQDLQNQQEI--ENLNS-----QINKLKNNLNSM 1324 Query: 1303 EEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQM 1362 E+ + LQ K +++ + L+S ++ +V + + + + Sbjct: 1325 EDKNQELQSKTNNLLQNVIDLQSSLQQLRVEKELIEQNNQLLQESLQKEKEEKEIAIRCQ 1384 Query: 1363 QEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQK-TH 1421 EQ +E +LK S+ + + LE+ Q E + Q T Sbjct: 1385 DEQ-----EKEYEKLKNSTICIDAHTQALDKLEIKNDQQKLEIEKQQEQLEQFAQQLITA 1439 Query: 1422 EYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESE 1481 E TI ++ + + Q+ Y K I +L+ + L ++ ++ +E Q E Sbjct: 1440 ETTIQSQKKQLDGHKIIQE--NYLKTISELSSK-------LNVEKKDSECQWEEEQDEKM 1490 Query: 1482 IERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEM-QTALENQEIEIVTLND 1538 I + K+ +S+ NK++ +++ E + T + +T++ + I L + Sbjct: 1491 ISLSTYEAQKFRKLLKSIDHNKKIPIMSQKNIEHIDITQALKKTSIIQESINFTKLEE 1548 Score = 113 bits (271), Expect = 5e-23 Identities = 167/846 (19%), Positives = 361/846 (42%), Gaps = 54/846 (6%) Query: 306 EKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKK 365 E+ +I EK + +AN+T L ++ + +Q +K+ + + E K ++S + Sbjct: 715 EEAKIIEKLNTRVANLTVLLQQSAKISFNQILRKQNDKQQKLQDKIFQQEQKLIASQEES 774 Query: 366 GSPLISRKSGRNTASK-MKSPWSQLSSETLNQ-DTDKKINKNEIAKLEMVIQSLNKDLVD 423 S K ++ + + + L+ D K+ +K+EI L I+S D+++ Sbjct: 775 QKEKNKYISFHEEKIKQIEQRYYSENKKVLSLLDQTKEQHKDEINLLNQKIKSQECDMIE 834 Query: 424 KEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQE 483 K + K +L + QQ + TE +++ K E Sbjct: 835 KTKQLKNAQEQIARLNSQISQKQKEYEELNKKSQQVENRLKTDNAKQVTELQSQLQKDSE 894 Query: 484 QLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVK------SNHKLKL 537 + K+ L D+ K + L++ + + ++D ++ KV+ N + +L Sbjct: 895 KYKKRLAQLETDLANKQSV--LQNQTKDFNNVKRDLDLKHEEYEKVQYELQQVQNERDRL 952 Query: 538 KQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESD 597 K+ + N + D E RL E+ L+++ L EK ++ D + D Sbjct: 953 KKDVMNLKNRIENLDQTVEKNRL--EIQQLNKQNQALNNEKQSIS---EDIQKDKQQVQD 1007 Query: 598 VYKKMIE----MENLAETRLKAISLLESQKFDL----VQELHILQQKYDEVEDKLADISQ 649 + K++ + +++L R + +S +ESQK DL ++ ++ +Q Y++ ++ + + Sbjct: 1008 LQKRLTQILDSVKSLESERSRLLSQIESQKLDLDKKKIEIDNLNKQVYEQSNERAQQLEK 1067 Query: 650 LQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNK 709 L Q+ ++K L EQ+ + ++ L+ D + IK L + E Sbjct: 1068 LMESQMNEKLKISALNEQVQIYKIEIDQFKTKMQILEADIQARDEKIKILNKNIETQKIT 1127 Query: 710 LQNYIQENMDLTDKLEKMSA--EKISELLAKINHE-EQSKIQ---TQFGIDAKIQERDLY 763 + ++ L + K+ A E+ ++L+ +N EQ+ I+ Q ++K E + Sbjct: 1128 IDENDKKIESLVSEQSKVIAENEQKNQLITNLNAAIEQALIECEIQQKNANSKKVELEEK 1187 Query: 764 IENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDEL 823 E + EL + ++ I L ++A ++R K +L ++E ++ + +++ Sbjct: 1188 QEEYKHELERLQNEINELGRNLATCKERERETNNKNVELIQQIEEANHNLNQKEQELNQI 1247 Query: 824 VNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKA 883 V + + +H E L ++ + KE L +E +NL L D+Q+ ++ Sbjct: 1248 VEEMNLNKNHINSNEMSLKQLNLDLKERDDYVSNLQDEVKNLTQQLEDLQRQD---LQNQ 1304 Query: 884 NRTDLAESESTKYQTQLRDLESNLKRITHEHQTL---IVQKKKEIEDLEIEFN-TQIESA 939 + S+ K + L +E + + + L ++ + ++ L +E + + Sbjct: 1305 QEIENLNSQINKLKNNLNSMEDKNQELQSKTNNLLQNVIDLQSSLQQLRVEKELIEQNNQ 1364 Query: 940 IRDKKVLNEKYEKNIEYVTQ--LEAQLQEYKNNIENLNMNVEELNKMNLELIDK--HVQK 995 + + + EK EK I Q E + ++ KN+ ++ + + L+K+ ++ + ++K Sbjct: 1365 LLQESLQKEKEEKEIAIRCQDEQEKEYEKLKNSTICIDAHTQALDKLEIKNDQQKLEIEK 1424 Query: 996 QQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTT 1055 QQ Q + +Q I + + KQ D I + +S +S + E K ++ Sbjct: 1425 QQEQLEQFAQQLITAETTIQSQKKQLDGHKIIQENYLKT--ISELSSKLNVEKKDSECQW 1482 Query: 1056 KLENMEEEMQRVS-------KQLLDSKQHNEELQILVR---EQDDQIKELKETKLTFE-M 1104 + E +E+M +S ++LL S HN+++ I+ + E D + LK+T + E + Sbjct: 1483 E-EEQDEKMISLSTYEAQKFRKLLKSIDHNKKIPIMSQKNIEHIDITQALKKTSIIQESI 1541 Query: 1105 NIPKTE 1110 N K E Sbjct: 1542 NFTKLE 1547 Score = 104 bits (249), Expect = 2e-20 Identities = 167/826 (20%), Positives = 363/826 (43%), Gaps = 76/826 (9%) Query: 795 LERKADQLGSYLQE-KQKAYSEYTIQEDELVNRLAV-----LMDHDRVVEKQLLEIEHEN 848 +E + D+ Y KQ EY ++++E++ L L+++ + +E+E++N Sbjct: 546 IENEHDEKDKYFDLFKQLELPEYGLKQEEMIADLKKELQMNLLNNKHKKDPHQIELEYQN 605 Query: 849 KELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLK 908 EL +NQI+ +N+ ++L + N + DL ++T Q Q+ LE L Sbjct: 606 SEL--RNQIMKLKNEIEMLNLKRKDDNSNIQI------DLLTKKNTLLQDQINKLEQQLN 657 Query: 909 RITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYK 968 ++ + ++ + K I L+ + + + + A ++ + +K K Y++ A Q Sbjct: 658 QVNNSNEYV-----KAISSLQKQLDER-DKAYQNLHLYYQKDNKE-NYIS---AANQNDA 707 Query: 969 NNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTE---QYINEINKLNALLKQKDEEI 1025 NN N + + K+N + + V QQ+ + + + ++ KL + Q+++++ Sbjct: 708 NNAVNKTEEAKIIEKLNTRVANLTVLLQQSAKISFNQILRKQNDKQQKLQDKIFQQEQKL 767 Query: 1026 IALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQIL- 1084 IA ++ + Y+S +E K+ Q + + +++ + Q +QH +E+ +L Sbjct: 768 IASQEESQKEKNKYISF---HEEKIKQIEQRYYSENKKVLSLLDQT--KEQHKDEINLLN 822 Query: 1085 --VREQD-DQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXX 1141 ++ Q+ D I++ K+ K E I + I E ++ N Sbjct: 823 QKIKSQECDMIEKTKQLKNAQEQ-IARLNSQISQKQKE--YEELNKKSQQVENRLKTDNA 879 Query: 1142 LKVQEEEEFIQERSV-LQEQSAKLNTELQECYTKIIQLETLNTELTGHDV-VNQEQINQL 1199 +V E + +Q+ S +++ A+L T+L + ++Q +T + D+ + E+ ++ Sbjct: 880 KQVTELQSQLQKDSEKYKKRLAQLETDLANKQS-VLQNQTKDFNNVKRDLDLKHEEYEKV 938 Query: 1200 KSKLEQLNTENDNLLSTVAELRSSISS---AVDQRGFEIAELWKQHLA--QREADFQKTE 1254 + +L+Q+ E D L V L++ I + V++ EI +L KQ+ A + + Sbjct: 939 QYELQQVQNERDRLKKDVMNLKNRIENLDQTVEKNRLEIQQLNKQNQALNNEKQSISEDI 998 Query: 1255 HELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTME-QVTSLQNKLQDKEEHLRNLQEKY 1313 + + Q+ + + Q+LDSV+S E + + +E Q L K + + + + E+ Sbjct: 999 QKDKQQVQDLQKRLTQILDSVKSLESERSRLLSQIESQKLDLDKKKIEIDNLNKQVYEQS 1058 Query: 1314 ADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYK---QMQEQSIL-- 1368 + Q+E L +EK+ +T+ Q + Q +++ I Sbjct: 1059 NERAQQLEKLMESQMNEKLKISALNEQVQIYKIEID-QFKTKMQILEADIQARDEKIKIL 1117 Query: 1369 --NINEENAQLKKSSXXXXXXXXXXXXRVNDAEAK---VLELTHQLE--LKDSEIYQKT- 1420 NI + + ++ + + E K + L +E L + EI QK Sbjct: 1118 NKNIETQKITIDENDKKIESLVSEQSKVIAENEQKNQLITNLNAAIEQALIECEIQQKNA 1177 Query: 1421 HEYTITLTQRNDEFENVRQQLV-EYEKRIEDLTYEKESELA-----ILRLKMHENANHYE 1474 + + L ++ +E+++ ++L E + +L KE E + ++ E ANH Sbjct: 1178 NSKKVELEEKQEEYKHELERLQNEINELGRNLATCKERERETNNKNVELIQQIEEANH-N 1236 Query: 1475 TMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALEN--QEIE 1532 QKE E+ ++ +EE+N+ S + +LN L+E + +Q ++N Q++E Sbjct: 1237 LNQKEQELNQI--VEEMNLNKNHINSNEMSLKQLNLDLKERDDYVSNLQDEVKNLTQQLE 1294 Query: 1533 IVTLNDEITNLQNMVRASS--SKIQKHVSFASDTKQGRDEQLDNTM 1576 + D + N Q + +S +K++ +++ D Q + +N + Sbjct: 1295 DLQRQD-LQNQQEIENLNSQINKLKNNLNSMEDKNQELQSKTNNLL 1339 Score = 93.1 bits (221), Expect = 6e-17 Identities = 210/1127 (18%), Positives = 467/1127 (41%), Gaps = 82/1127 (7%) Query: 477 EIAKVQEQLKQELN--DEIKDVNVKDLIEKLKSAEEQITQLNDEIDA-ANKNMIKVKSNH 533 +++K+ + +N ++IK + K+ E++ S + QI I +N+N+ +K Sbjct: 297 DVSKMDQWKSHCINHYEKIKKTHSKEQ-EEISSLKRQIKDQQATIQQLSNENIETIKKFD 355 Query: 534 KLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVD-YDSGR 592 L+ T+ +F+ V + K + + + + Q L+ N L D Sbjct: 356 DQCLEGKNYTLTSFNGVYEEYKNLRKCIQYIIDNQQDEYTLKTSLDNCMLQCQDKLKDQE 415 Query: 593 MIESDVYKKMIEMEN----LAETRLKAISLLESQKFDLVQELHILQQ-KYDEVEDKLADI 647 IE + + + + N + E++ K ++ + Q L+ L YD+++ DI Sbjct: 416 KIEKQITQYIDALGNYITSIWESKFKQFQRMQQYQQKFTQILNGLNTITYDKLKSLEPDI 475 Query: 648 SQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIM 707 S+L+ D S++ + KE++ E L YG + E M Sbjct: 476 SRLEKD--ISDLTKPYTF--FTNFKVILKEVSRRNEFNSLLDNPNYGKCMPKDFIPELNM 531 Query: 708 NKLQNYIQENMDLTDKLEKMSAEKIS--ELLAKINHEEQSKIQTQFGIDAKIQERDLYIE 765 N ++ Y Q N + K+E EK +L ++ E Q + D K ++L + Sbjct: 532 N-VKPYPQ-NYEKLPKIENEHDEKDKYFDLFKQLELPEYGLKQEEMIADLK---KELQMN 586 Query: 766 NIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVN 825 + ++ K +I LE + + ++ L+ + + L L+ K IQ D L Sbjct: 587 LLNNKHKKDPHQI-ELEYQNSELRNQIMKLKNEIEMLN--LKRKD---DNSNIQIDLLTK 640 Query: 826 RLAVLMDHDRVVEKQLLEIEHENK------ELQKKNQILLEENQNLQISLS-DMQQHYNA 878 + +L D +E+QL ++ + N+ LQK+ + QNL + D +++Y Sbjct: 641 KNTLLQDQINKLEQQLNQVNNSNEYVKAISSLQKQLDERDKAYQNLHLYYQKDNKENY-- 698 Query: 879 LVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIES 938 + AN+ D + + + ++ +E R+ + T+++Q + +I FN + Sbjct: 699 -ISAANQNDANNAVNKTEEAKI--IEKLNTRVAN--LTVLLQ-----QSAKISFNQILRK 748 Query: 939 AIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQT 998 ++ L +K + + + + + Q+ KN ++ + E++ ++ ++ K+ Sbjct: 749 QNDKQQKLQDKIFQQEQKLIASQEESQKEKNKY--ISFHEEKIKQIEQRYYSEN--KKVL 804 Query: 999 QSPDYT-EQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKL 1057 D T EQ+ +EIN LN +K ++ ++I +++ NAQ ++ S+++Q + Sbjct: 805 SLLDQTKEQHKDEINLLNQKIKSQECDMIEKTKQLKNAQ----EQIARLNSQISQKQKEY 860 Query: 1058 ENMEEEMQRVSKQL-LDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISS 1116 E + ++ Q+V +L D+ + ELQ +++ ++ K+ E ++ + ++ + Sbjct: 861 EELNKKSQQVENRLKTDNAKQVTELQSQLQKDSEKYKK---RLAQLETDLANKQSVLQNQ 917 Query: 1117 TIEPMSDDANNVDXXXXXXXXXXXXLK-VQEEEEFIQERSV-LQEQSAKLNTELQECYTK 1174 T + ++ ++D L+ VQ E + +++ + L+ + L+ +++ + Sbjct: 918 T-KDFNNVKRDLDLKHEEYEKVQYELQQVQNERDRLKKDVMNLKNRIENLDQTVEKNRLE 976 Query: 1175 IIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFE 1234 I QL N L E I + K +++ L +L +V L S S + Q + Sbjct: 977 IQQLNKQNQALNNEKQSISEDIQKDKQQVQDLQKRLTQILDSVKSLESERSRLLSQIESQ 1036 Query: 1235 IAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTS 1294 +L K+ + + Q E + Q+ + ++ S E +I +E + Sbjct: 1037 KLDLDKKKIEIDNLNKQVYEQSNERAQQLEKLMESQMNEKLKISALNEQVQIYKIE-IDQ 1095 Query: 1295 LQNKLQDKEEHLRNLQEKYADVINQIEILRSEIE--DEKVAFXXXXXXXXXXXXXXXXDL 1352 + K+Q E ++ EK + IE + I+ D+K+ L Sbjct: 1096 FKTKMQILEADIQARDEKIKILNKNIETQKITIDENDKKIESLVSEQSKVIAENEQKNQL 1155 Query: 1353 RTE-NQSYKQMQEQSIL---NINEENAQLKKSSXXXXXXXXXXXXRVNDAE---AKVLEL 1405 T N + +Q + + N N + +L++ +N+ A E Sbjct: 1156 ITNLNAAIEQALIECEIQQKNANSKKVELEEKQEEYKHELERLQNEINELGRNLATCKER 1215 Query: 1406 THQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLK 1465 + K+ E+ Q+ E L Q+ E + +++ + I E L L L Sbjct: 1216 ERETNNKNVELIQQIEEANHNLNQKEQELNQIVEEMNLNKNHINS----NEMSLKQLNLD 1271 Query: 1466 MHENANHYETMQKESE--IERVKLIEELNVKITESV-SLNKQVAELNKALEEEVAKTNEM 1522 + E ++ +Q E + ++++ ++ +++ + + +LN Q+ +L L K E+ Sbjct: 1272 LKERDDYVSNLQDEVKNLTQQLEDLQRQDLQNQQEIENLNSQINKLKNNLNSMEDKNQEL 1331 Query: 1523 QTALENQEIEIVTLNDEITNL---QNMVRASSSKIQKHVSFASDTKQ 1566 Q+ N ++ L + L + ++ ++ +Q+ + + K+ Sbjct: 1332 QSKTNNLLQNVIDLQSSLQQLRVEKELIEQNNQLLQESLQKEKEEKE 1378 Score = 68.5 bits (160), Expect = 1e-09 Identities = 184/946 (19%), Positives = 382/946 (40%), Gaps = 98/946 (10%) Query: 718 MDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSR 777 MD T+ ++ L + N + Q +D+K + D EL+ + + Sbjct: 121 MDNTEAAVNFFQQEQENQLKQFNKISLDAKKPQIKLDSKYADTDY---QYPVELNDGQKQ 177 Query: 778 ICRLE-ESIAVMEDRRY----SLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMD 832 + +L+ ++I +E + Y S++RKA + Q+ ++A EY IQ + L +++ Sbjct: 178 LVQLKNQNILELEQKFYKFYSSIKRKAYEFIQKWQKVERASKEYEIQYKSIECLLMRVIN 237 Query: 833 HDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESE 892 +V + E+ + K L N+++ + Q + SL + + D+ + + Sbjct: 238 EYQVSKNLSTEMHQKIKNL---NEVVSKSVQKYEESLK--------IGKNVELPDVLKKD 286 Query: 893 STKYQTQLRDLESNLKRITH--EHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKV-LNEK 949 + KY L D+ ++ ++ H +K K+ E E + ++ I+D++ + + Sbjct: 287 NKKY---LYDIYYDVSKMDQWKSHCINHYEKIKKTHSKEQEEISSLKRQIKDQQATIQQL 343 Query: 950 YEKNIEYVTQLEAQLQEYKN-NIENLNMNVEE---LNKMNLELIDKHVQKQ--QTQSPDY 1003 +NIE + + + Q E KN + + N EE L K +ID + +T + Sbjct: 344 SNENIETIKKFDDQCLEGKNYTLTSFNGVYEEYKNLRKCIQYIIDNQQDEYTLKTSLDNC 403 Query: 1004 TEQYINEINKLNALLKQKDEEIIALNQKINN---AQVSYMSMVSDYESKLAQFTT----- 1055 Q +++ + KQ + I AL I + ++ + Y+ K Q Sbjct: 404 MLQCQDKLKDQEKIEKQITQYIDALGNYITSIWESKFKQFQRMQQYQQKFTQILNGLNTI 463 Query: 1056 ---KLENMEEEMQRVSKQLLD-SKQHN--EELQILVRE--QDDQIKELKETKLTFEMNIP 1107 KL+++E ++ R+ K + D +K + +++++E + ++ L + + +P Sbjct: 464 TYDKLKSLEPDISRLEKDISDLTKPYTFFTNFKVILKEVSRRNEFNSLLDNP-NYGKCMP 522 Query: 1108 KTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTE 1167 K ++ ++P + + + ++ E + +E A L E Sbjct: 523 KDFIPELNMNVKPYPQNYEKLPKIENEHDEKDKYFDLFKQLELPEYGLKQEEMIADLKKE 582 Query: 1168 LQ-ECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVA-ELRSSIS 1225 LQ + + EL + + QI +LK+++E LN + + S + +L + + Sbjct: 583 LQMNLLNNKHKKDPHQIELEYQNSELRNQIMKLKNEIEMLNLKRKDDNSNIQIDLLTKKN 642 Query: 1226 SAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLL---------DSVQ 1276 + + + ++ + Q ++ K L+ QL + Y+ L + + Sbjct: 643 TLLQDQINKLEQQLNQ--VNNSNEYVKAISSLQKQLDERDKAYQNLHLYYQKDNKENYIS 700 Query: 1277 SSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADV-INQIEILRSEIEDEKVAFX 1335 ++ Q + N V + + KL + +L L ++ A + NQI LR + D++ Sbjct: 701 AANQNDANNAVNKTEEAKIIEKLNTRVANLTVLLQQSAKISFNQI--LRKQ-NDKQQKLQ 757 Query: 1336 XXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINE----ENAQ----LKKSSXXXXXX 1387 + + E Y E+ I I + EN + L ++ Sbjct: 758 DKIFQQEQKLIASQEESQKEKNKYISFHEEKIKQIEQRYYSENKKVLSLLDQTKEQHKDE 817 Query: 1388 XXXXXXRVNDAEAKVLELTHQLELK-------DSEIYQKTHEYTITLTQRNDEFENVRQQ 1440 ++ E ++E T QL+ +S+I QK EY L +++ + EN + Sbjct: 818 INLLNQKIKSQECDMIEKTKQLKNAQEQIARLNSQISQKQKEYE-ELNKKSQQVEN--RL 874 Query: 1441 LVEYEKRIEDLT--YEKESELAILRLKMHEN--ANHYETMQKES-EIERVKLIEELNVKI 1495 + K++ +L +K+SE RL E AN +Q ++ + VK +L + Sbjct: 875 KTDNAKQVTELQSQLQKDSEKYKKRLAQLETDLANKQSVLQNQTKDFNNVKRDLDLKHEE 934 Query: 1496 TESVSLN-KQVAELNKALEEEVA----KTNEMQTALENQEIEIVTLNDEITNLQNMVRAS 1550 E V +QV L+++V + + +E +EI LN + L N ++ Sbjct: 935 YEKVQYELQQVQNERDRLKKDVMNLKNRIENLDQTVEKNRLEIQQLNKQNQALNNEKQSI 994 Query: 1551 SSKIQKHVSFASDTKQGRDEQLDNTMNKE-----LLDAVPRAELDL 1591 S IQK D ++ + LD+ + E LL + +LDL Sbjct: 995 SEDIQKDKQQVQDLQKRLTQILDSVKSLESERSRLLSQIESQKLDL 1040 Score = 65.7 bits (153), Expect = 1e-08 Identities = 126/642 (19%), Positives = 272/642 (42%), Gaps = 66/642 (10%) Query: 147 LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXX 206 L N K+ +N L +K + E +LQ+ NE+D++ K Sbjct: 914 LQNQTKDFNNVKRDLDLKHEEYEKVQYELQQVQNERDRL---KKDVMNLKNRIENLDQTV 970 Query: 207 XXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEE-ANKLLEAARF 265 E QQ+ K + +EKQ + +DI+ ++ L++ ++L++ + Sbjct: 971 EKNRLE--IQQLNKQNQAL-------NNEKQSISEDIQKDKQQVQDLQKRLTQILDSVK- 1020 Query: 266 EISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEE------KGSLEIA 319 + E S+L ++E L KQ E S E ++E+ L+I+ Sbjct: 1021 SLESERSRLLSQIESQKLDLDKKKIEIDNLNKQVYEQSNERAQQLEKLMESQMNEKLKIS 1080 Query: 320 NMTELTK--KIEL------LEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLIS 371 + E + KIE+ ++ L I+ +++++ + T+ + KK L+S Sbjct: 1081 ALNEQVQIYKIEIDQFKTKMQILEADIQARDEKIKILNKNIETQKITIDENDKKIESLVS 1140 Query: 372 RKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEK 431 +S ++ K +QL + LN ++ + + EI + + + + +EY + Sbjct: 1141 EQSKVIAENEQK---NQLIT-NLNAAIEQALIECEIQQKNANSKKVELEEKQEEY---KH 1193 Query: 432 DTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELND 491 + G++ L + E + + + LI + + E Q +QELN Sbjct: 1194 ELERLQNEINELGRN-LATCKERERETNNKNVELI------QQIEEANHNLNQKEQELNQ 1246 Query: 492 EIKDVNVKDLIEKLKSAEEQITQLN---DEIDAANKNMIKVKSNHKLKLKQMQK-TIDNF 547 ++++N+ + S E + QLN E D N+ N +L+ +Q+ + N Sbjct: 1247 IVEEMNLNK--NHINSNEMSLKQLNLDLKERDDYVSNLQDEVKNLTQQLEDLQRQDLQNQ 1304 Query: 548 SKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMEN 607 ++ + N +I +L L+ + K EL+ + NL +++D S + + V K++IE N Sbjct: 1305 QEIENLNSQINKLKNNLNSMEDKNQELQSKTNNLLQNVIDLQSS-LQQLRVEKELIEQNN 1363 Query: 608 LAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKL----ADISQLQSDQVCSEIKSVH 663 + +++ + +K ++ +++Y+++++ A L ++ ++ + + Sbjct: 1364 --QLLQESLQKEKEEKEIAIRCQDEQEKEYEKLKNSTICIDAHTQALDKLEIKNDQQKLE 1421 Query: 664 LEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDI--------MNKLQNYIQ 715 +E+Q + L ++L ++ K+QL G EN + I + K + Q Sbjct: 1422 IEKQQEQLEQFAQQLITAETTIQSQKKQLDGHKIIQENYLKTISELSSKLNVEKKDSECQ 1481 Query: 716 ENMDLTDKLEKMS---AEKISELLAKINHEEQSKIQTQFGID 754 + +K+ +S A+K +LL I+H ++ I +Q I+ Sbjct: 1482 WEEEQDEKMISLSTYEAQKFRKLLKSIDHNKKIPIMSQKNIE 1523 >UniRef50_A0DDB5 Cluster: Chromosome undetermined scaffold_46, whole genome shotgun sequence; n=1; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_46, whole genome shotgun sequence - Paramecium tetraurelia Length = 1356 Score = 133 bits (321), Expect = 4e-29 Identities = 216/1152 (18%), Positives = 498/1152 (43%), Gaps = 81/1152 (7%) Query: 474 DVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNH 533 D++ I+ Q ++ D+ + +D +E +A++ + + K SN+ Sbjct: 122 DIDTISTAQSIADEQTTDKKQPGQTQDKLETESTAKKNSIESQQIKPLQIDDSSKQNSNN 181 Query: 534 KLKLKQMQKTIDNFSKVSD------SNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVD 587 +L ++ I+ +VS S I +L++EL L + AE++++ NL + + Sbjct: 182 TQQLSDKEQAINLAKQVSPLAPSPLSQINIQQLSDELGELRKVNAEIKDQN-NLLIQEIQ 240 Query: 588 YDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADI 647 + ++++ ++ ++ ++ + + I+ + Q D + L++ E E ++ Sbjct: 241 KE--KLLKDELIQQFQNLKRQLDNSIN-INKYQDQILDYDKRAQQLKEALQESEISKENL 297 Query: 648 S-QLQSD-QVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKED 705 S Q QS Q+ S ++ +A K+ +E L+ + +++Y KD+ N + Sbjct: 298 SKQYQSTLQLYSGLQD-EFNTVKEAFLIEKENAKTFMEKLQ-ENQEIYKQ-KDVANQELT 354 Query: 706 IMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQ----FGIDAKIQERD 761 I N Q+ +Q +D+ ++ ++ + +S L + E ++I Q ++ +IQ++ Sbjct: 355 IKN--QSQLQRIIDVESQINLLNQQILS--LNRQKEESNNEILQQKDYIIQLEQQIQQQH 410 Query: 762 LYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLG-SYLQEKQKAYSEYTIQE 820 ++ + +I + ++ I ++ + + ++K +Q+ + Q+ ++ E I Sbjct: 411 FQCSSLNDQKKSIDQQIQQYQQQIQELQSQLLNQQQKMNQMKIQFQQDSEQNRKESQINN 470 Query: 821 DELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEE-NQNLQISLSDMQQHYNAL 879 +L + + +++++ L+IE +E ++ + E Q + + ++Q +L Sbjct: 471 QKLQDYSQKISEYEKLQNDTQLKIEKMIEEHSQEIKNCSESIYQGVMPQIKQLKQEIASL 530 Query: 880 VEKANRTDLAESESTKYQTQLRDL-ESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIES 938 E+AN L + + + + + + + E+ LK+ H + + Q +K I D+ F E+ Sbjct: 531 -EQANLVQLEQLKVQESKNEEQTIRETQLKQSIHSSEAQLTQLQKLISDI---FG---ET 583 Query: 939 AIRDKKVLN-EKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQ 997 I K+ LN E +EK E L + + I L ++ LN +K+ + + Sbjct: 584 QILMKQFLNQENFEKETELPNILSKLHSQINSKINKLQSEIDLLNSQIQLQDEKYKDRSK 643 Query: 998 TQSPDYTEQYIN---EINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFT 1054 +Q +Q N EIN L ++ + L+ + N + + + + E K +F Sbjct: 644 SQQDCLIDQLSNKNCEINDLKLAIENLKNQNQFLHHENENIKKNVNEITNQLEQKQNEFQ 703 Query: 1055 T-KLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELK----------ETKLTFE 1103 KL N E+ +Q +KQL D + N+ELQ+ ++ + + +E++ + K+ Sbjct: 704 QLKLIN-EDNIQTQTKQLKDQQNLNQELQLKLKNFESESQEIQNSQQNKIKNADVKINEL 762 Query: 1104 MNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQ-SA 1162 +N K + II+ + + N+ K+QE++ I++ + Q Q Sbjct: 763 LNELKQQENIINDQSHKLKE--GNMIIQDYTKKNQELLNKIQEQQYQIEQNTFQQSQYEI 820 Query: 1163 KLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLS----TVA 1218 K QE Q+ LN +L E++ + + E + EN+ + T+ Sbjct: 821 KQKAIQQENAELQEQINLLNLQLQSFQEKIPEEVQRNAKEYEDIINENNQKIQEQQRTIK 880 Query: 1219 ELRSSISSAVDQ--RGFEIAELWKQHLAQREADFQKT-----EHELRVQLSAFESKYEQL 1271 +L I + +++ + + E + Q++ ++ +T E EL++ AF + ++ Sbjct: 881 QLEQQIKAQMEEYKQNLDQQEQLHKKEFQKQNEYNQTTIQQLEEELKISKQAFLEQKIKI 940 Query: 1272 LDSVQSSTQEE-TNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDE 1330 +S Q+ Q++ N +E + + N ++ + + L + Q++ + E + Sbjct: 941 DESQQNQNQDQLQNSQSIIENLQLVNNTIKQQHQELELQHNNLKQHLVQVD--KKNQEQQ 998 Query: 1331 KVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSIL--NINEENAQLKKSSXXXXXXX 1388 ++ D +N ++ S L ++ E QL + Sbjct: 999 QLLGQQQNQITTLQQKVKEMDGIIKNLEIEKNSISSKLTNDLQELQQQLFSENDEWQKEK 1058 Query: 1389 XXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRI 1448 +V D EA+ L L+ K+ ++ E I L +N ++Q++ E +K Sbjct: 1059 EIIQKQVEDLEAQNEGLKETLKEKEQQLLM-IQEQNIALKSQNQLLNEIQQKVQELDKEN 1117 Query: 1449 ED--LTYEKE-SEL-AILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQ 1504 ++ L ++++ E+ + L++ N ++++++SE+ + I EL +I + K Sbjct: 1118 KNNKLKWQQQVDEMNSNSNLQIQNLTNQIQSLEQQSEVYKAD-INELKRQINQKDDDIKL 1176 Query: 1505 VAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDT 1564 + E +K L+ + +N E E+ I L ++ Q S + Q + F Sbjct: 1177 IEEKSK-LDNQYLNSNYNNKLREQDEL-IQQLQTDLQQFQQ----SEVEQQSLIKFLESA 1230 Query: 1565 KQGRDE-QLDNT 1575 K+ ++ Q++N+ Sbjct: 1231 KENLEKLQIENS 1242 Score = 127 bits (307), Expect = 2e-27 Identities = 238/1201 (19%), Positives = 515/1201 (42%), Gaps = 111/1201 (9%) Query: 305 EEKTEIEEKGSLEIANMTELTKK---IELLEHLNCQIRQTNKELENKLATMGTESKAVSS 361 E+ T+ ++ G + TE T K IE + QI ++K+ N + + +A++ Sbjct: 135 EQTTDKKQPGQTQDKLETESTAKKNSIESQQIKPLQIDDSSKQNSNNTQQLSDKEQAINL 194 Query: 362 PSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTD--KKINKNEIAKLEMVIQSLNK 419 +K+ SPL SP SQ++ + L+ + +K+N + ++IQ + K Sbjct: 195 -AKQVSPLAP------------SPLSQINIQQLSDELGELRKVNAEIKDQNNLLIQEIQK 241 Query: 420 DLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIA 479 + + K+ +I + L + + +L + E++++ Sbjct: 242 EKLLKDELIQQFQNLKRQLDNSININKYQDQILDYDKRAQQLKEALQESEISKENLSKQY 301 Query: 480 KVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVK--SNHKLKL 537 + QL L DE V LIEK ++A+ + +L + N+ + K K +N +L + Sbjct: 302 QSTLQLYSGLQDEFNTVKEAFLIEK-ENAKTFMEKLQE-----NQEIYKQKDVANQELTI 355 Query: 538 K---QMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHL-VDYDSGRM 593 K Q+Q+ ID S+++ N++I+ L + + ++ L+++ +QL + + Sbjct: 356 KNQSQLQRIIDVESQINLLNQQILSLNRQKEESNNEI--LQQKDYIIQLEQQIQQQHFQC 413 Query: 594 IESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSD 653 + KK I+ + + + I L+SQ + Q+++ ++ ++ + ++ SQ+ + Sbjct: 414 SSLNDQKKSIDQQ--IQQYQQQIQELQSQLLNQQQKMNQMKIQFQQDSEQNRKESQINNQ 471 Query: 654 QVCSEIKSVHLEEQI--DALSASKKELALVIENLKLDKEQLY-GTIKDLENDKEDIMNKL 710 ++ + + E++ D +K + + +K E +Y G + ++ K++I + Sbjct: 472 KLQDYSQKISEYEKLQNDTQLKIEKMIEEHSQEIKNCSESIYQGVMPQIKQLKQEIASLE 531 Query: 711 Q-NYIQ-ENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQ------FGIDAKIQERDL 762 Q N +Q E + + + + + ++L I+ E Q Q FG + ++ L Sbjct: 532 QANLVQLEQLKVQESKNEEQTIRETQLKQSIHSSEAQLTQLQKLISDIFGETQILMKQFL 591 Query: 763 YIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYT-IQED 821 EN E E ++ + + +L I + L+ + D L S +Q + + Y + + Q+D Sbjct: 592 NQENFEKE-TELPNILSKLHSQI---NSKINKLQSEIDLLNSQIQLQDEKYKDRSKSQQD 647 Query: 822 ELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVE 881 L+++L+ ++ E L++ EN L+ +NQ L EN+N++ +++++ Sbjct: 648 CLIDQLS-----NKNCEINDLKLAIEN--LKNQNQFLHHENENIKKNVNEITNQLEQKQN 700 Query: 882 KANRTDLAESESTKYQT-QLRD-------LESNLKRITHEHQTLIVQKKKEIEDLEIEFN 933 + + L ++ + QT QL+D L+ LK E Q + ++ +I++ +++ N Sbjct: 701 EFQQLKLINEDNIQTQTKQLKDQQNLNQELQLKLKNFESESQEIQNSQQNKIKNADVKIN 760 Query: 934 TQIESAIRDKKVLNEKYEKNIE---YVTQLEAQLQEYKNNIENLNMNVEE--LNKMNLEL 988 + + + ++N++ K E + + QE N I+ +E+ + E+ Sbjct: 761 ELLNELKQQENIINDQSHKLKEGNMIIQDYTKKNQELLNKIQEQQYQIEQNTFQQSQYEI 820 Query: 989 IDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYES 1048 K +Q++ + + +IN LN L+ E+I Q+ NA+ Y ++++ Sbjct: 821 KQKAIQQENAELQE-------QINLLNLQLQSFQEKIPEEVQR--NAK-EYEDIINENNQ 870 Query: 1049 KLAQFTTKLENMEEEMQRVS---KQLLDSKQ--HNEELQILVREQDDQIKELKETKLTFE 1103 K+ + ++ +E++++ KQ LD ++ H +E Q I++L+E + Sbjct: 871 KIQEQQRTIKQLEQQIKAQMEEYKQNLDQQEQLHKKEFQKQNEYNQTTIQQLEEELKISK 930 Query: 1104 MNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQE--QS 1161 + + I S D N +K Q +E +Q ++ Q Q Sbjct: 931 QAFLEQKIKIDESQQNQNQDQLQNSQSIIENLQLVNNTIKQQHQELELQHNNLKQHLVQV 990 Query: 1162 AKLNTELQECY-TKIIQLETLNTELTGHD--VVNQE-QINQLKSKL-EQLNTENDNLLST 1216 K N E Q+ + Q+ TL ++ D + N E + N + SKL L L S Sbjct: 991 DKKNQEQQQLLGQQQNQITTLQQKVKEMDGIIKNLEIEKNSISSKLTNDLQELQQQLFSE 1050 Query: 1217 VAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYE-QLLDSV 1275 E + + Q+ ++ +L Q+ +E +K + L +Q K + QLL+ + Sbjct: 1051 NDEWQKE--KEIIQK--QVEDLEAQNEGLKETLKEKEQQLLMIQEQNIALKSQNQLLNEI 1106 Query: 1276 QSSTQE-----ETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDE 1330 Q QE + NK+ +QV + + + ++NL + + Q E+ +++I + Sbjct: 1107 QQKVQELDKENKNNKLKWQQQVDEMNS---NSNLQIQNLTNQIQSLEQQSEVYKADINEL 1163 Query: 1331 KVAFXXXXXXXXXXXXXXXXDLRTENQSYKQM---QEQSILNINEENAQLKKSSXXXXXX 1387 K D + N +Y Q++ I + + Q ++S Sbjct: 1164 KRQINQKDDDIKLIEEKSKLDNQYLNSNYNNKLREQDELIQQLQTDLQQFQQSEVEQQSL 1223 Query: 1388 XXXXXXRVNDAEAKVLE---LTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEY 1444 + E +E T +++L + ++ +K EY + + + EN+ Q+L + Sbjct: 1224 IKFLESAKENLEKLQIENSEYTQRIQLANDKMSEKIKEYEVKIISLKETIENLEQRLNQL 1283 Query: 1445 E 1445 E Sbjct: 1284 E 1284 Score = 109 bits (263), Expect = 5e-22 Identities = 218/1015 (21%), Positives = 440/1015 (43%), Gaps = 109/1015 (10%) Query: 152 KEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXX 211 K+KD A L +K + I+D++ +IN +Q I + N+ Sbjct: 344 KQKDVANQELTIKNQSQLQRIIDVESQINLLNQQILSLNRQKEESNNEILQQKDYIIQLE 403 Query: 212 EDTKQQ------MTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLE-EANKLLEAAR 264 + +QQ + +++ +++ + Q L + ++ +++ ++ + + E R Sbjct: 404 QQIQQQHFQCSSLNDQKKSIDQQIQQYQQQIQELQSQLLNQQQKMNQMKIQFQQDSEQNR 463 Query: 265 FEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTEL 324 E + + KL ++ + K E S E K E + + +L Sbjct: 464 KESQINNQKLQDYSQKISEYEKLQNDTQLKIEKMIEEHSQEIKNCSESIYQGVMPQIKQL 523 Query: 325 TKKIELLEHLN-CQIRQTN-KELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKM 382 ++I LE N Q+ Q +E +N+ T+ S S + +K + + Sbjct: 524 KQEIASLEQANLVQLEQLKVQESKNEEQTIRETQLKQSIHSSEAQLTQLQKLISDIFGET 583 Query: 383 KSPWSQ-LSSETLNQDTD-----KKIN---KNEIAKLEMVIQSLNK--DLVDKEYVISEK 431 + Q L+ E ++T+ K++ ++I KL+ I LN L D++Y K Sbjct: 584 QILMKQFLNQENFEKETELPNILSKLHSQINSKINKLQSEIDLLNSQIQLQDEKYKDRSK 643 Query: 432 DTXXXXXXXXXXGKDTLIAQLQLEHQQ-HMEGPSLIHVGTN-TEDVNEIAKVQEQLKQEL 489 + K+ I L+L + + L H N ++VNEI EQ + E Sbjct: 644 -SQQDCLIDQLSNKNCEINDLKLAIENLKNQNQFLHHENENIKKNVNEITNQLEQKQNEF 702 Query: 490 ND--EIKDVNVKDLIEKLKSAE--EQITQL--------NDEIDAANKNMIK---VKSNHK 534 I + N++ ++LK + Q QL + EI + +N IK VK N Sbjct: 703 QQLKLINEDNIQTQTKQLKDQQNLNQELQLKLKNFESESQEIQNSQQNKIKNADVKINEL 762 Query: 535 L-KLKQMQKTI-DNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGR 592 L +LKQ + I D K+ + N I T++ L K+ E Q + ++ ++ + Sbjct: 763 LNELKQQENIINDQSHKLKEGNMIIQDYTKKNQELLNKIQE--------QQYQIEQNTFQ 814 Query: 593 MIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQEL-HILQQKYDEVEDKLADISQLQ 651 + ++ +K I+ EN AE + + I+LL Q +++ +Q+ E ED + + +Q Sbjct: 815 QSQYEIKQKAIQQEN-AELQ-EQINLLNLQLQSFQEKIPEEVQRNAKEYEDIINENNQKI 872 Query: 652 SDQVCSEIKSVHLEEQIDALSASKKELALVIENL---KLDKEQLYG--TIKDLENDKEDI 706 +Q IK LE+QI A K+ E L + K+ Y TI+ LE E++ Sbjct: 873 QEQQ-RTIK--QLEQQIKAQMEEYKQNLDQQEQLHKKEFQKQNEYNQTTIQQLE---EEL 926 Query: 707 MNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIEN 766 Q ++++ + + + + + +++ + I E + I + QE +L N Sbjct: 927 KISKQAFLEQKIKIDESQQNQNQDQLQNSQSII--ENLQLVNNT--IKQQHQELELQHNN 982 Query: 767 IESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQ----EKQKAYSEYTIQEDE 822 ++ L + + ++ + +++ +L++K ++ ++ EK S+ T E Sbjct: 983 LKQHLVQVDKKNQEQQQLLGQQQNQITTLQQKVKEMDGIIKNLEIEKNSISSKLTNDLQE 1042 Query: 823 LVNRLAVLMD----HDRVVEKQLLEIEHENKEL-----QKKNQILLEENQNLQISLSDMQ 873 L +L D +++KQ+ ++E +N+ L +K+ Q+L+ + QN I+L Sbjct: 1043 LQQQLFSENDEWQKEKEIIQKQVEDLEAQNEGLKETLKEKEQQLLMIQEQN--IALKSQN 1100 Query: 874 QHYNALVEKANRTDLA-ESESTKYQTQLRDLESN----LKRITHEHQTLIVQK---KKEI 925 Q N + +K D ++ K+Q Q+ ++ SN ++ +T++ Q+L Q K +I Sbjct: 1101 QLLNEIQQKVQELDKENKNNKLKWQQQVDEMNSNSNLQIQNLTNQIQSLEQQSEVYKADI 1160 Query: 926 EDLEIEFNTQ------IESAIR-DKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNV 978 +L+ + N + IE + D + LN Y + +L QLQ + + Sbjct: 1161 NELKRQINQKDDDIKLIEEKSKLDNQYLNSNYNNKLREQDELIQQLQTDLQQFQQSEVEQ 1220 Query: 979 EELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVS 1038 + L K LE ++++K Q ++ +YT++ +K++ +K+ + +II+L + I N Sbjct: 1221 QSLIKF-LESAKENLEKLQIENSEYTQRIQLANDKMSEKIKEYEVKIISLKETIEN---- 1275 Query: 1039 YMSMVSDYESKLAQFTTKLENMEEE-MQRVSKQLLDSKQHNEELQILVREQDDQI 1092 E +L Q + N +++ +Q V + L+++K E Q++ + QD+ I Sbjct: 1276 -------LEQRLNQLEFENSNHKQQVLQPVVENLIENKSQKESNQLIEQLQDEII 1323 Score = 106 bits (254), Expect = 6e-21 Identities = 206/993 (20%), Positives = 423/993 (42%), Gaps = 90/993 (9%) Query: 642 DKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLEN 701 D ++ + +Q + + +++++ S +KK IE+ ++ Q+ + K N Sbjct: 124 DTISTAQSIADEQTTDKKQPGQTQDKLETESTAKKNS---IESQQIKPLQIDDSSKQNSN 180 Query: 702 DKEDIMNKLQ--NYIQENMDLTDK-LEKMSAEKISELLAKINH-EEQSKIQTQFGIDAKI 757 + + + +K Q N ++ L L +++ +++S+ L ++ + K Q I +I Sbjct: 181 NTQQLSDKEQAINLAKQVSPLAPSPLSQINIQQLSDELGELRKVNAEIKDQNNLLIQ-EI 239 Query: 758 QERDLYIENIESELSKYKSRICRLEESIAV--MEDRRYSLERKADQLGSYLQEKQKAYSE 815 Q+ L + + + K + L+ SI + +D+ +++A QL LQE + + Sbjct: 240 QKEKLLKDELIQQFQNLKRQ---LDNSININKYQDQILDYDKRAQQLKEALQESEISKEN 296 Query: 816 YTIQEDELVNRLAVLMDHDRVVEKQLLEIEHEN-KELQKKNQILLEENQNLQISLSDMQQ 874 + Q + + L D V++ L IE EN K +K L+ENQ + Q Sbjct: 297 LSKQYQSTLQLYSGLQDEFNTVKEAFL-IEKENAKTFMEK----LQENQEIYKQKDVANQ 351 Query: 875 HYNALVEKANRTDLAESESTKYQTQLRDLES-NLKRITHEHQTLIVQKKKEIEDLEIEFN 933 N++ L + Q L + + +L R E I+Q+K I LE + Sbjct: 352 ELTI----KNQSQLQRIIDVESQINLLNQQILSLNRQKEESNNEILQQKDYIIQLEQQIQ 407 Query: 934 TQIE--SAIRD-KKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELID 990 Q S++ D KK ++++ ++ + + +L++QL + + + + ++ ++ N + + Sbjct: 408 QQHFQCSSLNDQKKSIDQQIQQYQQQIQELQSQLLNQQQKMNQMKIQFQQDSEQNRK--E 465 Query: 991 KHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALN-QKINNAQVSYMSMVSDYESK 1049 + Q+ Q DY+++ I+E KL + K E++I + Q+I N S V + Sbjct: 466 SQINNQKLQ--DYSQK-ISEYEKLQNDTQLKIEKMIEEHSQEIKNCSESIYQGVMPQIKQ 522 Query: 1050 LAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKT 1109 L Q LE +Q ++ +SK + ++ +Q E + T+L ++ Sbjct: 523 LKQEIASLEQANL-VQLEQLKVQESKNEEQTIRETQLKQSIHSSEAQLTQLQKLISDIFG 581 Query: 1110 EGMIISSTI---EPMSDDANNVDXXXXXXXXXXXXL-KVQEEEEFIQERSVLQEQSAKLN 1165 E I+ E + + + K+Q E + + + LQ++ K Sbjct: 582 ETQILMKQFLNQENFEKETELPNILSKLHSQINSKINKLQSEIDLLNSQIQLQDEKYKDR 641 Query: 1166 TELQE-CYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSI 1224 ++ Q+ C I QL N E+ + I LK++ + L+ EN+N+ V E+ + + Sbjct: 642 SKSQQDCL--IDQLSNKNCEINDLKLA----IENLKNQNQFLHHENENIKKNVNEITNQL 695 Query: 1225 SSAVDQRGFEIAELWKQHLAQREA----DFQKTEHELRVQLSAFESKYEQLLDSVQSSTQ 1280 Q F+ +L + Q + D Q EL+++L FES+ +++ +S Q+ + Sbjct: 696 EQK--QNEFQQLKLINEDNIQTQTKQLKDQQNLNQELQLKLKNFESESQEIQNSQQNKIK 753 Query: 1281 EETNKI-VTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXX 1339 KI + ++ +N + D+ L+ D + + L ++I++++ Sbjct: 754 NADVKINELLNELKQQENIINDQSHKLKEGNMIIQDYTKKNQELLNKIQEQQYQIEQNTF 813 Query: 1340 XXXXXXXXXXXDLRTENQSYKQMQEQ-SILNINEENAQLKKSSXXXXXXXXXXXXRVNDA 1398 ++ EN ++QEQ ++LN+ ++ Q +K +N+ Sbjct: 814 QQSQYEIKQKA-IQQENA---ELQEQINLLNLQLQSFQ-EKIPEEVQRNAKEYEDIINEN 868 Query: 1399 EAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKR-IEDLTYE-KE 1456 K+ E ++ + +I + EY L Q+ + Q+ EY + I+ L E K Sbjct: 869 NQKIQEQQRTIKQLEQQIKAQMEEYKQNLDQQEQLHKKEFQKQNEYNQTTIQQLEEELKI 928 Query: 1457 SELAILRLKM-----HENANHYETMQKESEIERVKLI--------EELNVKITES----V 1499 S+ A L K+ +N N + +S IE ++L+ +EL ++ V Sbjct: 929 SKQAFLEQKIKIDESQQNQNQDQLQNSQSIIENLQLVNNTIKQQHQELELQHNNLKQHLV 988 Query: 1500 SLNKQVAELNKALEEEV-------AKTNEMQTALENQEIEIVTLNDEITN----LQNMVR 1548 ++K+ E + L ++ K EM ++N EIE +++ ++TN LQ + Sbjct: 989 QVDKKNQEQQQLLGQQQNQITTLQQKVKEMDGIIKNLEIEKNSISSKLTNDLQELQQQLF 1048 Query: 1549 ASSSKIQKHVSFASDTKQGRDEQLDNTMNKELL 1581 + + + QK KQ D + N KE L Sbjct: 1049 SENDEWQKEKEIIQ--KQVEDLEAQNEGLKETL 1079 Score = 99.1 bits (236), Expect = 9e-19 Identities = 205/995 (20%), Positives = 426/995 (42%), Gaps = 112/995 (11%) Query: 144 VTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXX 203 + L I+++ S L + K ++ I Q++I E + + + Sbjct: 399 IIQLEQQIQQQHFQCSSLNDQKKSIDQQIQQYQQQIQELQSQLLNQQQKMNQMKIQFQQD 458 Query: 204 XXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEA-----NK 258 + Q++ + E D + ++ K IE I + E+ Sbjct: 459 SEQNRKESQINNQKLQDYSQKISEYEKLQNDTQLKIEKMIEEHSQEIKNCSESIYQGVMP 518 Query: 259 LLEAARFEI-SLEHSKLAQELEQXXXXXXXXXXXXX--XLAKQSIEPSCEEKTEIEEKGS 315 ++ + EI SLE + L Q LEQ KQSI S + T++++ S Sbjct: 519 QIKQLKQEIASLEQANLVQ-LEQLKVQESKNEEQTIRETQLKQSIHSSEAQLTQLQKLIS 577 Query: 316 LEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSG 375 +I T++ K + LN + + EL N L+ + S+ S +K S + S Sbjct: 578 -DIFGETQILMK----QFLNQENFEKETELPNILSKL--HSQINSKINKLQSEIDLLNSQ 630 Query: 376 RNTASKMKSPWSQLSSETLNQDTDKKINKN-EIAKLEMVIQSLNKDLVDKEYVISEKDTX 434 + S+ + L D+ NKN EI L++ I++L +++ E + Sbjct: 631 IQLQDEKYKDRSKSQQDCL---IDQLSNKNCEINDLKLAIENLKNQ---NQFLHHENENI 684 Query: 435 XXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQEL-NDEI 493 + Q Q E QQ ++ + ++ T T+ + + + ++L+ +L N E Sbjct: 685 KKNVNEIT----NQLEQKQNEFQQ-LKLINEDNIQTQTKQLKDQQNLNQELQLKLKNFES 739 Query: 494 KDVNVKDLIE-KLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQM------QKTIDN 546 + +++ + K+K+A+ +I +L +E+ +N+I +S HKLK M +K + Sbjct: 740 ESQEIQNSQQNKIKNADVKINELLNELKQ-QENIINDQS-HKLKEGNMIIQDYTKKNQEL 797 Query: 547 FSKVSDSNKEIVRLT--EELHHLSQKV-----AELEEEKGNLQLHLVDYDSGRMIESDVY 599 +K+ + +I + T + + + QK AEL+E+ L L L + I +V Sbjct: 798 LNKIQEQQYQIEQNTFQQSQYEIKQKAIQQENAELQEQINLLNLQLQSFQE--KIPEEVQ 855 Query: 600 KKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEI 659 + E E++ + I + L Q++ ++Y + D+ + + + Q +E Sbjct: 856 RNAKEYEDIINENNQKIQEQQRTIKQLEQQIKAQMEEYKQNLDQQEQLHKKEF-QKQNEY 914 Query: 660 KSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMD 719 +++ + L SK+ A + + +K+D+ Q +N +D + Q+ I EN+ Sbjct: 915 NQTTIQQLEEELKISKQ--AFLEQKIKIDESQ--------QNQNQDQLQNSQSII-ENLQ 963 Query: 720 LTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRIC 779 L + K + EL + N+ +Q +Q +D K QE+ + +++++ + ++ Sbjct: 964 LVNNTIKQQHQ---ELELQHNNLKQHLVQ----VDKKNQEQQQLLGQQQNQITTLQQKVK 1016 Query: 780 RLEESIAVMEDRRYSLERKADQLGSYLQE-KQKAYSEYTIQEDELVNRLAVLMDHDRVVE 838 ++ I +E + S+ K L + LQE +Q+ +SE DE +++ Sbjct: 1017 EMDGIIKNLEIEKNSISSK---LTNDLQELQQQLFSE----NDEW-------QKEKEIIQ 1062 Query: 839 KQLLEIEHENKEL-----QKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLA-ESE 892 KQ+ ++E +N+ L +K+ Q+L+ + QN I+L Q N + +K D ++ Sbjct: 1063 KQVEDLEAQNEGLKETLKEKEQQLLMIQEQN--IALKSQNQLLNEIQQKVQELDKENKNN 1120 Query: 893 STKYQTQLRDLESN----LKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNE 948 K+Q Q+ ++ SN ++ +T++ Q+L Q + D+ E QI D K++ E Sbjct: 1121 KLKWQQQVDEMNSNSNLQIQNLTNQIQSLEQQSEVYKADIN-ELKRQINQKDDDIKLIEE 1179 Query: 949 KYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYI 1008 K + + +Y+ Y N + + +++L + +L+ + +QQ+ + E Sbjct: 1180 KSKLDNQYLNS------NYNNKLREQDELIQQL-QTDLQQFQQSEVEQQSLIK-FLESAK 1231 Query: 1009 NEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVS 1068 + KL + + I N K++ + +YE K+ +EN+E+ + ++ Sbjct: 1232 ENLEKLQIENSEYTQRIQLANDKMSEK-------IKEYEVKIISLKETIENLEQRLNQLE 1284 Query: 1069 KQLLDSKQHNEELQILVREQDDQIKELKETKLTFE 1103 ++ H +++ V E + K KE+ E Sbjct: 1285 ---FENSNHKQQVLQPVVENLIENKSQKESNQLIE 1316 Score = 41.9 bits (94), Expect = 0.14 Identities = 69/369 (18%), Positives = 143/369 (38%), Gaps = 33/369 (8%) Query: 147 LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQII-EAKNKATTXXXXXXXXXXX 205 ++NTIK++ L + +K ++ + +K E+ Q++ + +N+ TT Sbjct: 965 VNNTIKQQHQELELQHNNLK---QHLVQVDKKNQEQQQLLGQQQNQITTLQQKVKEMDGI 1021 Query: 206 XXXXXXEDTK------QQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKL 259 E + ++Q+ + EW+ EK+ + K +E + + L+E L Sbjct: 1022 IKNLEIEKNSISSKLTNDLQELQQQLFSENDEWQKEKEIIQKQVEDLEAQNEGLKET--L 1079 Query: 260 LEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIA 319 E + + ++ +A L+ L K++ + + +++E S Sbjct: 1080 KEKEQQLLMIQEQNIA--LKSQNQLLNEIQQKVQELDKENKNNKLKWQQQVDEMNSNSNL 1137 Query: 320 NMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTA 379 + LT +I+ LE + + EL+ ++ + K + SK + ++ S N Sbjct: 1138 QIQNLTNQIQSLEQQSEVYKADINELKRQINQKDDDIKLIEEKSKLDNQYLN--SNYNNK 1195 Query: 380 SKMKSPWSQLSSETLNQDTDKKINKNEIAK-LEMVIQSLNK-DLVDKEYV---------- 427 + + Q L Q ++ + + K LE ++L K + + EY Sbjct: 1196 LREQDELIQQLQTDLQQFQQSEVEQQSLIKFLESAKENLEKLQIENSEYTQRIQLANDKM 1255 Query: 428 ---ISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQ 484 I E + + + QL+ E+ H + L V N + N+ K Q Sbjct: 1256 SEKIKEYEVKIISLKETIENLEQRLNQLEFENSNHKQ-QVLQPVVENLIE-NKSQKESNQ 1313 Query: 485 LKQELNDEI 493 L ++L DEI Sbjct: 1314 LIEQLQDEI 1322 >UniRef50_A0CZE8 Cluster: Chromosome undetermined scaffold_32, whole genome shotgun sequence; n=3; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_32, whole genome shotgun sequence - Paramecium tetraurelia Length = 1064 Score = 133 bits (321), Expect = 4e-29 Identities = 202/960 (21%), Positives = 416/960 (43%), Gaps = 88/960 (9%) Query: 623 KFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVI 682 +F+ ++EL + ++ + +L + Q+ ++ + +E+ I + + EL Sbjct: 99 QFNRIKELEGVNEQQEIRIRELQTKLESQTTEISNYKLKSEIEKHIIRIKQLESELNEYK 158 Query: 683 ENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQE-NMDLTD------KLEKMSAEKISEL 735 L + L G +K+ E +D +L N+ + N D T+ +L + +K EL Sbjct: 159 SKLGSVDQSLAGRLKEAERKLQDSDKELTNWKNKYNTDKTNWDNEIRRLNDLLTQKQKEL 218 Query: 736 LAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSL 795 N++ ++ Q Q ++++ + I ES++S YKS I RL + ++ +R + Sbjct: 219 DDYKNNQGKNYEQLQ----QQLRQYETKIREYESQISTYKSDIDRLNK---LLLERNSEI 271 Query: 796 ERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQK-K 854 +R ++L + LQE S++T +++ N + ++ + +++ +++L K Sbjct: 272 DRLKNELKTRLQELDDWRSKFTNLQNQF-NTMK--SQYESKINDLTNTLQNRDRDLNDWK 328 Query: 855 NQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEH 914 N+ E Q + S + + + NR +S+ + TQLRD ++ ++ + + Sbjct: 329 NKYAKLEGQFNNLG-SLQSGSESKITDLQNRLSQLQSDFDRQATQLRDRDAQIQALKEKL 387 Query: 915 QTLIVQK---KKEIEDLEIEFNTQI-ESAIRDKKVLNEKYEKNI--EYVTQLEAQLQEYK 968 Q L +++DL+ +N + E+ ++ N K E + + + Q QL+ Y+ Sbjct: 388 QRLEQDNFNLNNQLQDLQSRYNNLLKENEKLQNELRNRKNELDFMKQQLQQANDQLKRYE 447 Query: 969 NNIENLNMNVEELNK--MNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEII 1026 + I LN + E M L+ + +++Q + + E+ N L+ KD++I Sbjct: 448 DQINQLNEQIMECKDQIMALQNSKEMLERQLQDLYSKSNDNVGELKSANDQLEGKDKDIA 507 Query: 1027 ALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVR 1086 L ++N QV M ES ++ +L N +E+QR+ Q Q ELQ Sbjct: 508 DLRDQLNQFQVDRQIM----ESMISSLNNQLANKNDEIQRLLAQNKLRLQQLLELQSRYA 563 Query: 1087 EQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANN--VDXXXXXXXXXXXXLKV 1144 + D + +LK +L + I + S ++ + DD K+ Sbjct: 564 QLDYLLSDLKGVELQNKQLIARI------SELQQLVDDLKRKLAQQELQLLQSKSNEFKI 617 Query: 1145 QEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLE 1204 QE E I+E L ++ +LN L + K+ + + LN ++ + + +IN+LK+ LE Sbjct: 618 QELENIIKE---LAKEIQRLNEFLNQ---KLSENDKLNMQI----ISMENEINKLKN-LE 666 Query: 1205 QLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAF 1264 L E + L T + + + +D R E+ E W+ ++ E + + +L + F Sbjct: 667 PLLRELEKKLQTHLDDIARLKQLLDSRTNELNE-WRLKYSKLEPVIDE-KRQLEEKNRLF 724 Query: 1265 ESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNK-----------LQDKEEHLRNLQEKY 1313 E++ + L ++ T++ K + ++Q+ + N+ + E L NLQ Y Sbjct: 725 ENRIQGLHQDIERLTKQLRQKQLDIDQLNWILNQTEGLLRNRDDSINSLETRLNNLQRSY 784 Query: 1314 ADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEE 1373 D Q + +I+ + DL N++ K++ Q N N++ Sbjct: 785 -DNERQKTLNFEQIQSQLQQAVDKINQLETQIKGLQNDL---NRAKKEVTYQQ--NENDQ 838 Query: 1374 NAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRND- 1432 Q S R + E ++ + ++E + K Y L Q N Sbjct: 839 MRQQIAKSEITILDLKQNEARFKEVENRLNQSQKEVEKLTRQFNDKLQAYE-ELKQNNGL 897 Query: 1433 ---EFENVRQQLVEYEKRIEDLTYEKESELAILR---LKMHENANHYE--------TM-Q 1477 +++N++QQ E +R+ L + ++ IL+ L++ N Y+ T+ Q Sbjct: 898 LDTKYKNLQQQYQELLQRLNQLE-QINNQYQILKAKNLELENNNKQYKIDQDRLNSTLNQ 956 Query: 1478 KESEIERVK-LIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTL 1536 K E+ ++ L+ +L KI + ++ A + E+E+ K++E+Q + QE ++ L Sbjct: 957 KLQELNELQNLLPQLEDKIHQLTPFEEKYAIVQPKYEQELNKSDELQRKIRGQEQQLQEL 1016 Score = 118 bits (285), Expect = 1e-24 Identities = 177/818 (21%), Positives = 366/818 (44%), Gaps = 103/818 (12%) Query: 331 LEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLS 390 ++ LN + + N E++ + T + + K + L + S+ +S + L+ Sbjct: 257 IDRLNKLLLERNSEIDRLKNELKTRLQELDDWRSKFTNL--QNQFNTMKSQYESKINDLT 314 Query: 391 SETLNQDTDKKINKNEIAKLEMVIQSLNK-------DLVDKEYVISEKDTXXXXXXXXXX 443 + N+D D KN+ AKLE +L + D + +S+ + Sbjct: 315 NTLQNRDRDLNDWKNKYAKLEGQFNNLGSLQSGSESKITDLQNRLSQLQSDFDRQATQLR 374 Query: 444 GKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDV----NEIAKVQEQLKQELNDEIKDVN-- 497 +D I L+ E Q +E + ++ +D+ N + K E+L+ EL + +++ Sbjct: 375 DRDAQIQALK-EKLQRLEQDNF-NLNNQLQDLQSRYNNLLKENEKLQNELRNRKNELDFM 432 Query: 498 ---VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSN 554 ++ ++LK E+QI QLN++I ++ ++++ ++ +Q+Q D +SK +D+ Sbjct: 433 KQQLQQANDQLKRYEDQINQLNEQIMECKDQIMALQNSKEMLERQLQ---DLYSKSNDNV 489 Query: 555 KEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMEN--LAETR 612 E+ ++L + +A+L ++ Q ++ + + MI N LA Sbjct: 490 GELKSANDQLEGKDKDIADLRDQLNQFQ-----------VDRQIMESMISSLNNQLANKN 538 Query: 613 LKAISLLESQKFDLVQELHILQQKYDEVEDKLADIS--QLQSDQVCSEIKSVHLEEQIDA 670 + LL K L Q+L LQ +Y +++ L+D+ +LQ+ Q+ + I L++ +D Sbjct: 539 DEIQRLLAQNKLRL-QQLLELQSRYAQLDYLLSDLKGVELQNKQLIARISE--LQQLVDD 595 Query: 671 LSA--SKKELALVIENLKLDK-EQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKM 727 L +++EL L+ K ++L IK+L + + + L + EN L ++ M Sbjct: 596 LKRKLAQQELQLLQSKSNEFKIQELENIIKELAKEIQRLNEFLNQKLSENDKLNMQIISM 655 Query: 728 SAEKISEL--LAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLE--- 782 E I++L L + E + K+QT A++++ +++ +EL++++ + +LE Sbjct: 656 ENE-INKLKNLEPLLRELEKKLQTHLDDIARLKQ---LLDSRTNELNEWRLKYSKLEPVI 711 Query: 783 -------ESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDR 835 E + E+R L + ++L L++KQ + ++ L D Sbjct: 712 DEKRQLEEKNRLFENRIQGLHQDIERLTKQLRQKQLDIDQLNWILNQTEGLLRNRDDSIN 771 Query: 836 VVEKQL--LEIEHENK--------ELQKKNQILLEENQNLQISLSDMQQHYNALVEKA-- 883 +E +L L+ ++N+ ++Q + Q +++ L+ + +Q N ++ Sbjct: 772 SLETRLNNLQRSYDNERQKTLNFEQIQSQLQQAVDKINQLETQIKGLQNDLNRAKKEVTY 831 Query: 884 --NRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIR 941 N D + K + + DL+ N R E + + Q +KE+E L +FN +++ A Sbjct: 832 QQNENDQMRQQIAKSEITILDLKQNEARFK-EVENRLNQSQKEVEKLTRQFNDKLQ-AYE 889 Query: 942 DKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSP 1001 + K N + + + Q +L + N +E +N + L NLEL + + Sbjct: 890 ELKQNNGLLDTKYKNLQQQYQELLQRLNQLEQINNQYQILKAKNLELENNN--------- 940 Query: 1002 DYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENME 1061 +QY + ++LN+ L QK +E+ N Q +++ E K+ Q T E Sbjct: 941 ---KQYKIDQDRLNSTLNQKLQEL-------NELQ----NLLPQLEDKIHQLTP----FE 982 Query: 1062 EEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETK 1099 E+ V + ++ELQ +R Q+ Q++EL++ K Sbjct: 983 EKYAIVQPKYEQELNKSDELQRKIRGQEQQLQELEKVK 1020 Score = 107 bits (258), Expect = 2e-21 Identities = 200/1014 (19%), Positives = 427/1014 (42%), Gaps = 94/1014 (9%) Query: 469 GTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEK----LKSAEEQITQLNDEIDAANK 524 G N + I ++Q +L+ + EI + +K IEK +K E ++ + ++ + ++ Sbjct: 108 GVNEQQEIRIRELQTKLESQTT-EISNYKLKSEIEKHIIRIKQLESELNEYKSKLGSVDQ 166 Query: 525 NMIKVKSNHKLKLKQMQKTIDNFSKVSDSNK-----EIVRLTEELHHLSQKVAELEEEKG 579 ++ + KL+ K + N+ +++K EI RL + L +QK EL++ K Sbjct: 167 SLAGRLKEAERKLQDSDKELTNWKNKYNTDKTNWDNEIRRLNDLL---TQKQKELDDYKN 223 Query: 580 NLQLHLVDYDSG-RMIESDV--YKKMIEMENLAETRLKAISLLESQKFD-LVQELHILQQ 635 N + R E+ + Y+ I RL + L + + D L EL Q Sbjct: 224 NQGKNYEQLQQQLRQYETKIREYESQISTYKSDIDRLNKLLLERNSEIDRLKNELKTRLQ 283 Query: 636 KYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGT 695 + D+ K ++ Q Q + + S+ +S + + + L ++L +N E + Sbjct: 284 ELDDWRSKFTNL-QNQFNTMKSQYES-KINDLTNTLQNRDRDLN-DWKNKYAKLEGQFNN 340 Query: 696 IKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDA 755 + L++ E + LQN + + D+ ++ +++ A + + Q Q F ++ Sbjct: 341 LGSLQSGSESKITDLQNRLSQLQSDFDRQATQLRDRDAQIQA-LKEKLQRLEQDNFNLNN 399 Query: 756 KIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSE 815 ++Q+ N+ E K ++ + + + M+ + L++ DQL Y + ++ Sbjct: 400 QLQDLQSRYNNLLKENEKLQNELRNRKNELDFMKQQ---LQQANDQLKRY----EDQINQ 452 Query: 816 YTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQH 875 Q E +++ L + ++E+QL ++ ++ + + + ++ + ++D++ Sbjct: 453 LNEQIMECKDQIMALQNSKEMLERQLQDLYSKSNDNVGELKSANDQLEGKDKDIADLRDQ 512 Query: 876 YNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDL-EIEFN- 933 N + D ES + L + L E Q L+ Q K ++ L E++ Sbjct: 513 LNQF-----QVDRQIMES-----MISSLNNQLANKNDEIQRLLAQNKLRLQQLLELQSRY 562 Query: 934 TQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHV 993 Q++ + D K + + ++ I +++L+ + + K + +EL + + + + Sbjct: 563 AQLDYLLSDLKGVELQNKQLIARISELQQLVDDLKRKLAQ-----QELQLLQSKSNEFKI 617 Query: 994 QKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQF 1053 Q+ + + ++ EI +LN L QK E LN +I + + + ++ + + E L + Sbjct: 618 QELE----NIIKELAKEIQRLNEFLNQKLSENDKLNMQIISME-NEINKLKNLEPLLREL 672 Query: 1054 TTKLENMEEEMQRVSKQLLDSKQHN-EELQILVREQD---DQIKELKETKLTFEMNIPKT 1109 KL+ +++ R+ KQLLDS+ + E ++ + + D+ ++L+E FE I Sbjct: 673 EKKLQTHLDDIARL-KQLLDSRTNELNEWRLKYSKLEPVIDEKRQLEEKNRLFENRIQGL 731 Query: 1110 EGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQ 1169 I T + + ++D L+ +++ + +LN LQ Sbjct: 732 HQDIERLT-KQLRQKQLDIDQLNWILNQTEGLLRNRDDS--------INSLETRLNN-LQ 781 Query: 1170 ECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSIS---S 1226 Y Q +TLN E Q Q+ Q K+ QL T+ L + + + ++ + Sbjct: 782 RSYDNERQ-KTLNFEQI------QSQLQQAVDKINQLETQIKGLQNDLNRAKKEVTYQQN 834 Query: 1227 AVDQRGFEIA--ELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETN 1284 DQ +IA E+ L Q EA F++ E+ L E Q D +Q+ + + N Sbjct: 835 ENDQMRQQIAKSEITILDLKQNEARFKEVENRLNQSQKEVEKLTRQFNDKLQAYEELKQN 894 Query: 1285 KIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRS---EIEDEKVAFXXXXXXX 1341 + + +LQ + Q+ + L L++ + NQ +IL++ E+E+ + Sbjct: 895 NGLLDTKYKNLQQQYQELLQRLNQLEQ----INNQYQILKAKNLELENNNKQYKIDQDRL 950 Query: 1342 XXXXXXXXXDLRTENQSYKQMQEQ--SILNINEENAQLKKSSXXXXXXXXXXXXRVNDAE 1399 +L Q++++ + E+ A ++ ++ E Sbjct: 951 NSTLNQKLQELNELQNLLPQLEDKIHQLTPFEEKYAIVQPKYEQELNKSDELQRKIRGQE 1010 Query: 1400 AKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTY 1453 ++ EL K +I Q + T+ LT E E +RQQ + + I+DL + Sbjct: 1011 QQLQELE-----KVKKIVQ---DQTVMLTVLFGECEGLRQQCTDKDGEIQDLRF 1056 Score = 82.2 bits (194), Expect = 1e-13 Identities = 135/655 (20%), Positives = 291/655 (44%), Gaps = 63/655 (9%) Query: 377 NTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXX 436 N ++S ++ L E + + KNE+ ++ +Q N L K Y +D Sbjct: 399 NQLQDLQSRYNNLLKENEKLQNELRNRKNELDFMKQQLQQANDQL--KRY----EDQINQ 452 Query: 437 XXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTED-VNEIAKVQEQLKQELND--EI 493 KD ++A L++ + M L + + + D V E+ +QL+ + D ++ Sbjct: 453 LNEQIMECKDQIMA---LQNSKEMLERQLQDLYSKSNDNVGELKSANDQLEGKDKDIADL 509 Query: 494 KDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDS 553 +D + +++ + E I+ LN+++ N + ++ + +KL+L+Q+ + ++++ Sbjct: 510 RDQLNQFQVDR-QIMESMISSLNNQLANKNDEIQRLLAQNKLRLQQLLELQSRYAQLDYL 568 Query: 554 NKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRL 613 ++ + + L +++EL++ +L+ L + + K+ E+EN+ + Sbjct: 569 LSDLKGVELQNKQLIARISELQQLVDDLKRKLAQQELQLLQSKSNEFKIQELENIIKELA 628 Query: 614 KAI---------SLLESQKFDL--------VQELHILQQKYDEVEDKLA----DISQLQS 652 K I L E+ K ++ + +L L+ E+E KL DI++L+ Sbjct: 629 KEIQRLNEFLNQKLSENDKLNMQIISMENEINKLKNLEPLLRELEKKLQTHLDDIARLKQ 688 Query: 653 --DQVCSEIKSVHLE-EQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNK 709 D +E+ L+ +++ + K++L E +L + ++ G +D+E + + K Sbjct: 689 LLDSRTNELNEWRLKYSKLEPVIDEKRQLE---EKNRLFENRIQGLHQDIERLTKQLRQK 745 Query: 710 LQNYIQEN--MDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENI 767 + Q N ++ T+ L + + I+ L ++N+ ++S D + +++ L E I Sbjct: 746 QLDIDQLNWILNQTEGLLRNRDDSINSLETRLNNLQRS-------YDNE-RQKTLNFEQI 797 Query: 768 ESELSKYKSRICRLEESIAVMED--RRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVN 825 +S+L + +I +LE I +++ R E Q + +Q A SE TI +L Sbjct: 798 QSQLQQAVDKINQLETQIKGLQNDLNRAKKEVTYQQNENDQMRQQIAKSEITIL--DLKQ 855 Query: 826 RLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQN---LQISLSDMQQHYNALVEK 882 A + + + + E+E ++ K Q E QN L ++QQ Y L+++ Sbjct: 856 NEARFKEVENRLNQSQKEVEKLTRQFNDKLQAYEELKQNNGLLDTKYKNLQQQYQELLQR 915 Query: 883 ANRTDLAESESTKYQTQLRDLESNLKRITHEHQTL---IVQKKKEIEDLEIEFNTQIESA 939 N+ + ++ + + +LE+N K+ + L + QK +E+ +L+ Q+E Sbjct: 916 LNQLEQINNQYQILKAKNLELENNNKQYKIDQDRLNSTLNQKLQELNELQ-NLLPQLEDK 974 Query: 940 IRDKKVLNEKYE-KNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHV 993 I EKY +Y +L + E + I ++EL K+ + D+ V Sbjct: 975 IHQLTPFEEKYAIVQPKYEQELN-KSDELQRKIRGQEQQLQELEKVKKIVQDQTV 1028 Score = 69.3 bits (162), Expect = 8e-10 Identities = 141/667 (21%), Positives = 276/667 (41%), Gaps = 81/667 (12%) Query: 931 EFNTQIESAIRDKKVLNEKYEKNI-EYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELI 989 E N Q + I++ + +NE+ E I E T+LE+Q E N L +E+ + + ++ + Sbjct: 95 ENNAQF-NRIKELEGVNEQQEIRIRELQTKLESQTTEISNY--KLKSEIEK-HIIRIKQL 150 Query: 990 DKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESK 1049 + + + +++ + + + L+ D+E+ K N + ++ + + Sbjct: 151 ESELNEYKSKLGSVDQSLAGRLKEAERKLQDSDKELTNWKNKYNTDKTNWDNEIRRLNDL 210 Query: 1050 LAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKE-----TKLTFEM 1104 L Q +L++ + + +QL +Q + + +RE + QI K KL E Sbjct: 211 LTQKQKELDDYKNNQGKNYEQL---QQQLRQYETKIREYESQISTYKSDIDRLNKLLLER 267 Query: 1105 NIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKL 1164 N +E + + ++ + ++ +K Q E + + LQ + L Sbjct: 268 N---SEIDRLKNELKTRLQELDDWRSKFTNLQNQFNTMKSQYESKINDLTNTLQNRDRDL 324 Query: 1165 NTELQECYTKII-QLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSS 1223 N + + Y K+ Q L + +G ++ +I L+++L QL ++ D +LR Sbjct: 325 N-DWKNKYAKLEGQFNNLGSLQSG----SESKITDLQNRLSQLQSDFDR---QATQLRD- 375 Query: 1224 ISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEET 1283 R +I L K+ L + E D L QL +S+Y LL + E Sbjct: 376 -------RDAQIQAL-KEKLQRLEQD----NFNLNNQLQDLQSRYNNLLKENEKLQNELR 423 Query: 1284 NKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXX 1343 N+ ++ ++ +LQ + L+ +Y D INQ+ E +D+ +A Sbjct: 424 NR---KNELDFMKQQLQQANDQLK----RYEDQINQLNEQIMECKDQIMALQNSKEM--- 473 Query: 1344 XXXXXXXDLRTENQSYKQMQEQSILNINEENAQLK-KSSXXXXXXXXXXXXRVNDA--EA 1400 L + Q ++ + N QL+ K +V+ E+ Sbjct: 474 --------LERQLQDLYSKSNDNVGELKSANDQLEGKDKDIADLRDQLNQFQVDRQIMES 525 Query: 1401 KVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELA 1460 + L +QL K+ EI + + + L QQL+E + R L Y S+L Sbjct: 526 MISSLNNQLANKNDEIQRLLAQNKLRL-----------QQLLELQSRYAQLDYLL-SDLK 573 Query: 1461 ILRLKMHEN-ANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAE-LNKALEEEVAK 1518 + L+ + A E Q +++R +EL + ++S Q E + K L +E+ + Sbjct: 574 GVELQNKQLIARISELQQLVDDLKRKLAQQELQLLQSKSNEFKIQELENIIKELAKEIQR 633 Query: 1519 TNEM--QTALENQEI--EIVTLNDEITNLQNM---VRASSSKIQKHVSFASDTKQGRDEQ 1571 NE Q EN ++ +I+++ +EI L+N+ +R K+Q H+ + KQ D + Sbjct: 634 LNEFLNQKLSENDKLNMQIISMENEINKLKNLEPLLRELEKKLQTHLDDIARLKQLLDSR 693 Query: 1572 LDNTMNK 1578 N +N+ Sbjct: 694 -TNELNE 699 Score = 41.1 bits (92), Expect = 0.25 Identities = 113/551 (20%), Positives = 218/551 (39%), Gaps = 53/551 (9%) Query: 144 VTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQI------IEAKNKATTXXX 197 ++ L+N + K++ + L + K+ +L+LQ + + D + +E +NK Sbjct: 527 ISSLNNQLANKNDEIQRLLAQNKLRLQQLLELQSRYAQLDYLLSDLKGVELQNKQLIARI 586 Query: 198 XXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEA------EWKDEKQRL-------LKDIE 244 + Q+ + + N ++ E E QRL L + + Sbjct: 587 SELQQLVDDLKRKLAQQELQLLQSKSNEFKIQELENIIKELAKEIQRLNEFLNQKLSEND 646 Query: 245 SKDVRISSLE-EANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAK-----Q 298 +++I S+E E NKL LE KL L+ L + Sbjct: 647 KLNMQIISMENEINKLKNLEPLLRELE-KKLQTHLDDIARLKQLLDSRTNELNEWRLKYS 705 Query: 299 SIEPSCEEKTEIEEKGSLEIANMTELTKKIE----LLEHLNCQIRQTNKELENKLATMGT 354 +EP +EK ++EEK L + L + IE L I Q N L + Sbjct: 706 KLEPVIDEKRQLEEKNRLFENRIQGLHQDIERLTKQLRQKQLDIDQLNWILNQTEGLLRN 765 Query: 355 ESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVI 414 +++S + + L ++S N K + + Q+ S+ L Q D KIN+ E +++ + Sbjct: 766 RDDSINSLETRLNNL--QRSYDNERQKTLN-FEQIQSQ-LQQAVD-KINQLE-TQIKGLQ 819 Query: 415 QSLNKDLVDKEYVISEKDTXXXXXXXXXXG-KDTLIAQLQLEHQQHMEGPSLIHVGTNTE 473 LN+ + Y +E D D + + + ++ S V T Sbjct: 820 NDLNRAKKEVTYQQNENDQMRQQIAKSEITILDLKQNEARFKEVENRLNQSQKEVEKLTR 879 Query: 474 DVNEIAKVQEQLKQELNDEIKDVNVKDL---IEKLKSAEEQITQLNDEIDAANKNMIKVK 530 N+ + E+LKQ N+ + D K+L ++L Q+ Q+N++ ++++ Sbjct: 880 QFNDKLQAYEELKQ--NNGLLDTKYKNLQQQYQELLQRLNQLEQINNQYQILKAKNLELE 937 Query: 531 SNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDS 590 +N+K + K Q ++ S ++ +E+ L L L K+ +L + + Y+ Sbjct: 938 NNNK-QYKIDQDRLN--STLNQKLQELNELQNLLPQLEDKIHQLTPFEEKYAIVQPKYEQ 994 Query: 591 GRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLV---QELHILQQ----KYDEVEDK 643 ++ +K+ E + K +++ Q L E L+Q K E++D Sbjct: 995 ELNKSDELQRKIRGQEQQLQELEKVKKIVQDQTVMLTVLFGECEGLRQQCTDKDGEIQDL 1054 Query: 644 LADISQLQSDQ 654 +++QL SDQ Sbjct: 1055 RFNVAQL-SDQ 1064 >UniRef50_A5DLM2 Cluster: Putative uncharacterized protein; n=1; Pichia guilliermondii|Rep: Putative uncharacterized protein - Pichia guilliermondii (Yeast) (Candida guilliermondii) Length = 1840 Score = 133 bits (321), Expect = 4e-29 Identities = 233/1171 (19%), Positives = 502/1171 (42%), Gaps = 122/1171 (10%) Query: 472 TEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKS 531 T D E+ KV K E ++ +KD +L KLK Q + + K+K Sbjct: 716 TRDFQELQKVVASTK-EASETVKD----ELNLKLKELTSQYENTEKSLSTTTWELNKLKE 770 Query: 532 NHKL---KLKQMQKTIDNFSKVSDS-NKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVD 587 HK+ KLK +Q+ + DS + +ELH ++ E +L L Sbjct: 771 AHKITEEKLKSLQEELSKTKAERDSLLASTKKFEKELHDTAKASESSNELVKSLTSKLAV 830 Query: 588 YDSGRMIESDVYKKM-IEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLAD 646 + GR D KM E+ NL + +A ++ + +L L +K DE+E L Sbjct: 831 AEEGRKKAEDGINKMNRELLNLTKLTKEAEKKAKTLENELNSLKKELSKKSDELEKGLKK 890 Query: 647 ISQLQS--DQVCSEIKSVHLE-EQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDK 703 ++Q +S +Q +++ +E E+ + +K+ LV + + E L ++ N Sbjct: 891 LAQEKSSVEQQLEQLRKQMIELEKSHQVQLKEKDEKLV--DTEASNEHLMDKLRSAGNAI 948 Query: 704 EDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQ------FGIDAKI 757 + + +++ Q+ +L +++ A + L+ + ++ + T+ I++ Sbjct: 949 QKMKAEMEKIEQKRKELDEQVAASKASVDAFLVTEEKYKTEISTLTKKTDEQTSEIESLK 1008 Query: 758 QER---DLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLG---SYLQEKQK 811 +E+ D I N+E+ L+K K+ L E E+ + L+++ ++L S L+E + Sbjct: 1009 EEKKALDEKILNVENNLTKVKAENEILTEK---SEEEKNKLKKQVEELEAKISSLKEDHE 1065 Query: 812 AYSEYTIQEDELVNR-LAVLMDHDRVVEKQL----LEIEHENKELQKKNQILLEENQNLQ 866 + S +QE EL+ + L V + + ++K++ ++ ++KEL++ ++ + LQ Sbjct: 1066 SKSLSGVQEKELLTKELQVAKEQLKKLQKEVSTKESQVLEKSKELEEATKLSDSKATALQ 1125 Query: 867 ISLSDMQ----QHYNALVEKANRTDLAESESTKYQTQLRDLESNL---KRITHEHQTLIV 919 + +M+ +H + L K S+ T+ Q ++ +LES L K E + + Sbjct: 1126 SEVDEMRKKLDEHESTLKTKEVELKEKTSQITEVQAKVEELESELLIAKTKLEEAEATSL 1185 Query: 920 QKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVE 979 + +E+++ + N+ + + + + E KN ++ ++E QL+E K +E Sbjct: 1186 KTTEELKETKSAENSARKQVAQLENEVKELKSKNADFAAEIE-QLKEQKTALELHKTTSS 1244 Query: 980 ELNKMNLELIDKHVQKQQTQ---SPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQ 1036 E + ++ +++ + K + Q + D ++ E++K A+ ++ E I + I + + Sbjct: 1245 EKHASSVAELEEAISKAKLQIKKNLDTLKKKDEEVSKSKAIAEKHVETISRHEKSIEDQK 1304 Query: 1037 VSYMSM---VSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIK 1093 + + VS+ + +LE ++Q ++ +L SK + + + + + K Sbjct: 1305 LKINELETRVSETNELKEKVRKELEQSASKLQELTDELSLSK---NDFRTKLEAAERRAK 1361 Query: 1094 ELKETKLTFEMNIPKTEGMIISST---IEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEF 1150 EL+ + E I + ++ +++ ++ S+ ++ + E+E Sbjct: 1362 ELEVSLSDKEKEIEQDRALLSANSETAVKEYSEKVTKLEASISELKKQNHEKVKEVEDEA 1421 Query: 1151 IQERSVLQEQSAKL---NTELQECYTKIIQLETLNTELTGH-DVVNQ------EQINQLK 1200 ++ +++E KL +L+E + I+++ L +L D +N+ EQ+ +LK Sbjct: 1422 ERQGQLVKELQKKLEGAEAKLKESSNENIKIDNLKNDLQKKLDTLNESFEEKDEQLKELK 1481 Query: 1201 -------SKLEQLNTENDNLLSTVAELRSSISSAVDQRG-----FEIAELWKQHLAQREA 1248 +L ++ E++ L + E ++ + SA D+ G E A + L + Sbjct: 1482 KEANQKTKQLSEIRAEHEGLKESAIESKNKLKSAEDEHGKTRTDLEAARKEVELLQEENE 1541 Query: 1249 DFQKTEHELRVQLSAFESKY----EQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEE 1304 +F + EL + + +++ E+L +S+ E K V+SLQ ++ + E Sbjct: 1542 EFDEKVEELENEKTKLDAQISTLKEELAKVKESNNSAEGEKHALESTVSSLQERISNLET 1601 Query: 1305 HLRNLQEKYADV-INQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQ 1363 L + K A+V N +IL E E K+ +L + + + Sbjct: 1602 SLSTYEAKIAEVDENDEKILELEKEVHKL---------KEEFEKQREELEKQRDENSKQK 1652 Query: 1364 EQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEY 1423 ++ NE Q++K S D AK E H++ +D +K + Sbjct: 1653 DEIAKQKNEALKQIEKLSQENDALRA-------DLGAKTEE--HKVYYED---VKKAQKE 1700 Query: 1424 TITLTQRNDEFENVRQQLVEYEKRIEDLTYEKE--SELAILRLKMH--ENANHYETMQKE 1479 ++TL Q+ V Q E + DL +E SE+A L KM E NH +Q++ Sbjct: 1701 SLTLEQK------VTQMTEEIRRLNLDLASSQETASEVARLETKMKSLEEENHKLELQRQ 1754 Query: 1480 SEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDE 1539 S ++ + + N + E V EL ++ V K+ +++ + + ++++ Sbjct: 1755 SGEREMEKLNQYNDSLREDV----VARELRPDAKQYVRKSE-----VDDLMLLMADMDEK 1805 Query: 1540 ITNLQNMVRASSSKIQKHVSFASDTKQGRDE 1570 I + +++ + S + + ++ D+ Sbjct: 1806 IQGYKKLLKKHGEDVSSDESLSEEEEEEEDD 1836 Score = 124 bits (298), Expect = 3e-26 Identities = 179/943 (18%), Positives = 417/943 (44%), Gaps = 80/943 (8%) Query: 49 ERQIKFERAQKC-LENAALVSKRIKEHRKATAELLGRPFVPGISESLANTLKQKEILMEK 107 E+Q++ R Q LE + V + K+ + E + + S N +++ + MEK Sbjct: 899 EQQLEQLRKQMIELEKSHQVQLKEKDEKLVDTEASNEHLMDKL-RSAGNAIQKMKAEMEK 957 Query: 108 IKQY-KELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNALSVLQVKMK 166 I+Q KEL ++ V +++ L+ E+ + + L+ + K Sbjct: 958 IEQKRKELDEQ-----VAASKASVDAFLVTEEKYKTEISTLTKKTDEQTSEIESLKEEKK 1012 Query: 167 IMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFI 226 ++ IL+++ + + ++A+N+ T E+ K ++ K E Sbjct: 1013 ALDEKILNVENNLTK----VKAENEILTEKS--------------EEEKNKLKKQVEELE 1054 Query: 227 AMEAEWK-DEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXX 285 A + K D + + L ++ K++ L+ A + L+ + E+S + S++ ++ ++ Sbjct: 1055 AKISSLKEDHESKSLSGVQEKELLTKELQVAKEQLKKLQKEVSTKESQVLEKSKELEEAT 1114 Query: 286 XXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLN--CQIRQTNK 343 L QS E E+ +K L+ T TK++EL E + +++ + Sbjct: 1115 KLSDSKATAL--QS------EVDEMRKK--LDEHESTLKTKEVELKEKTSQITEVQAKVE 1164 Query: 344 ELENKLATMGTESKAVSSPSKKGSP-LISRKSGRNTASKMKSPWSQLSSETLNQDTDKKI 402 ELE++L T+ + + S K + L KS N+A K + E +++ D Sbjct: 1165 ELESELLIAKTKLEEAEATSLKTTEELKETKSAENSARKQVAQLENEVKELKSKNADFAA 1224 Query: 403 NKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEG 462 ++ + + ++ L+K +++ S + K L L+ + ++ + Sbjct: 1225 EIEQLKEQKTALE-LHKTTSSEKHASSVAELEEAISKAKLQIKKNLDT-LKKKDEEVSKS 1282 Query: 463 PSLIHVGTNTEDVNEIAKVQEQLK-QELNDEIKDVN-VKDLIEK-LKSAEEQITQLNDEI 519 ++ T +E + ++LK EL + + N +K+ + K L+ + ++ +L DE+ Sbjct: 1283 KAIAEKHVETISRHEKSIEDQKLKINELETRVSETNELKEKVRKELEQSASKLQELTDEL 1342 Query: 520 DAANKNMIKVKSNH-KLKLKQMQKTIDNFSKVSDSNKEIVRLTEE--LHHLSQKVAELEE 576 + +KN + K + + K+++ ++ + K + ++ ++ E + S+KV +LE Sbjct: 1343 -SLSKNDFRTKLEAAERRAKELEVSLSDKEKEIEQDRALLSANSETAVKEYSEKVTKLEA 1401 Query: 577 EKGNL--QLH--LVDYDSGRMIESDVYKKMIEMENLAETRLKAIS----LLESQKFDLVQ 628 L Q H + + + + + K++ + AE +LK S +++ K DL + Sbjct: 1402 SISELKKQNHEKVKEVEDEAERQGQLVKELQKKLEGAEAKLKESSNENIKIDNLKNDLQK 1461 Query: 629 ELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLD 688 +L L + ++E +++L ++ + +++Q ++ + E + KE A+ +N Sbjct: 1462 KLDTLNESFEEKDEQLKELKK-EANQKTKQLSEIRAEHE------GLKESAIESKNKLKS 1514 Query: 689 KEQLYG-TIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEK---------ISELLAK 738 E +G T DLE ++++ LQ +EN + +K+E++ EK + E LAK Sbjct: 1515 AEDEHGKTRTDLEAARKEV-ELLQ---EENEEFDEKVEELENEKTKLDAQISTLKEELAK 1570 Query: 739 INHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERK 798 + S + +++ + I N+E+ LS Y+++I ++E+ + + + + Sbjct: 1571 VKESNNSAEGEKHALESTVSSLQERISNLETSLSTYEAKIAEVDENDEKILELEKEVHKL 1630 Query: 799 ADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQIL 858 ++ +E +K E + Q+DE+ + + + ++ + + +++++ Sbjct: 1631 KEEFEKQREELEKQRDENSKQKDEIAKQKNEALKQIEKLSQENDALRADLGAKTEEHKVY 1690 Query: 859 LEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLI 918 E+ + Q ++Q + E+ R +L + S + +++ LE+ +K + E+ L Sbjct: 1691 YEDVKKAQKESLTLEQKVTQMTEEIRRLNLDLASSQETASEVARLETKMKSLEEENHKLE 1750 Query: 919 VQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLE 961 +Q++ + E+E Q ++R+ V E +YV + E Sbjct: 1751 LQRQS--GEREMEKLNQYNDSLREDVVARELRPDAKQYVRKSE 1791 Score = 116 bits (278), Expect = 7e-24 Identities = 200/1089 (18%), Positives = 439/1089 (40%), Gaps = 69/1089 (6%) Query: 158 LSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQ 217 L+ L+ KI E + LQE++++ ++ +T E K Sbjct: 765 LNKLKEAHKITEEKLKSLQEELSKTKAERDSLLASTKKFEKELHDTAKASESSNELVKSL 824 Query: 218 MTKMQENFIAMEAEWKDEK--QRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLA 275 +K+ +A E K E ++ +++ + E+ K LE + E SK + Sbjct: 825 TSKLA---VAEEGRKKAEDGINKMNRELLNLTKLTKEAEKKAKTLENELNSLKKELSKKS 881 Query: 276 QELEQXXXXXXXXXXXXXX----LAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELL 331 ELE+ L KQ IE + +++EK + ++ L Sbjct: 882 DELEKGLKKLAQEKSSVEQQLEQLRKQMIELEKSHQVQLKEKDEKLVDTEASNEHLMDKL 941 Query: 332 EHLNCQIRQTNKELEN-KLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLS 390 I++ E+E + + + +S + + L++ + + S + + + Sbjct: 942 RSAGNAIQKMKAEMEKIEQKRKELDEQVAASKASVDAFLVTEEKYKTEISTLTKKTDEQT 1001 Query: 391 SETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIA 450 SE + +KK +I +E +L K + E + + + + I+ Sbjct: 1002 SEIESLKEEKKALDEKILNVE---NNLTKVKAENEILTEKSEEEKNKLKKQVEELEAKIS 1058 Query: 451 QLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEI--KDVNV----KDLIEK 504 L+ +H E SL V E+ +EQLK +L E+ K+ V K+L E Sbjct: 1059 SLKEDH----ESKSLSGVQEKELLTKELQVAKEQLK-KLQKEVSTKESQVLEKSKELEEA 1113 Query: 505 LKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEEL 564 K ++ + T L E+D K + + +S K K +++ + S++++ ++ L EL Sbjct: 1114 TKLSDSKATALQSEVDEMRKKLDEHESTLKTKEVELK---EKTSQITEVQAKVEELESEL 1170 Query: 565 HHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKF 624 K+ E E L + S E+ K++ ++EN + LK+ + + + Sbjct: 1171 LIAKTKLEEAEATSLKTTEELKETKSA---ENSARKQVAQLENEVK-ELKSKNADFAAEI 1226 Query: 625 DLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIEN 684 + ++E + + + S + ++ S+ K + +++ +D L +E++ Sbjct: 1227 EQLKEQKTALELHKTTSSEKHASSVAELEEAISKAK-LQIKKNLDTLKKKDEEVSKSKAI 1285 Query: 685 LKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEK---MSAEKISELLAKINH 741 + E + K +E+ K I N+L+ + E +L +K+ K SA K+ EL +++ Sbjct: 1286 AEKHVETISRHEKSIEDQKLKI-NELETRVSETNELKEKVRKELEQSASKLQELTDELSL 1344 Query: 742 EEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRI-CRLEESIAVMEDRRYSLERKAD 800 + + + +E ++ + + E E+ + ++ + E ++ ++ LE Sbjct: 1345 SKNDFRTKLEAAERRAKELEVSLSDKEKEIEQDRALLSANSETAVKEYSEKVTKLEASIS 1404 Query: 801 QLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLE 860 +L EK K + ++ +LV L ++ E +L E +EN ++ L + Sbjct: 1405 ELKKQNHEKVKEVEDEAERQGQLVKELQKKLEG---AEAKLKESSNENIKIDNLKNDLQK 1461 Query: 861 ENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQ 920 + L S + + L ++AN + TK +++R LK E + Sbjct: 1462 KLDTLNESFEEKDEQLKELKKEAN-------QKTKQLSEIRAEHEGLKESAIESK----N 1510 Query: 921 KKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEE 980 K K ED + T +E+A ++ ++L E+ E+ E V +LE + + I L + + Sbjct: 1511 KLKSAEDEHGKTRTDLEAARKEVELLQEENEEFDEKVEELENEKTKLDAQISTLKEELAK 1570 Query: 981 LNKMNLELI-DKHVQKQQTQS----PDYTEQYINEINKLNALLKQKDEEIIALNQKINNA 1035 + + N +KH + S E ++ A + + DE+I+ L ++++ Sbjct: 1571 VKESNNSAEGEKHALESTVSSLQERISNLETSLSTYEAKIAEVDENDEKILELEKEVHKL 1630 Query: 1036 QVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKEL 1095 + + + E + + + + + + ++ KQ+ Q N+ L+ + + ++ K Sbjct: 1631 KEEFEKQREELEKQRDENSKQKDEIAKQKNEALKQIEKLSQENDALRADLGAKTEEHKVY 1690 Query: 1096 KETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERS 1155 E ++ + E + + + M+++ ++ E + Sbjct: 1691 YE-----DVKKAQKESLTLEQKVTQMTEEIRRLNLDLASSQET-----ASEVARLETKMK 1740 Query: 1156 VLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLS 1215 L+E++ KL + Q ++ +L N L DVV +E K + + +E D+L+ Sbjct: 1741 SLEEENHKLELQRQSGEREMEKLNQYNDSLR-EDVVARELRPDAKQYVRK--SEVDDLML 1797 Query: 1216 TVAELRSSI 1224 +A++ I Sbjct: 1798 LMADMDEKI 1806 Score = 71.7 bits (168), Expect = 2e-10 Identities = 117/579 (20%), Positives = 234/579 (40%), Gaps = 72/579 (12%) Query: 1049 KLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPK 1108 KL + T++ EN E+ + + +L K+ ++ + ++ +++ + K + + + K Sbjct: 743 KLKELTSQYENTEKSLSTTTWELNKLKEAHKITEEKLKSLQEELSKTKAERDSLLASTKK 802 Query: 1109 TEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTEL 1168 E + + D A + L V EE R ++ K+N EL Sbjct: 803 FE--------KELHDTAKASESSNELVKSLTSKLAVAEEG-----RKKAEDGINKMNREL 849 Query: 1169 QECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAV 1228 + L L E + ++N LK +L + + E + L +A+ +SS+ + Sbjct: 850 -------LNLTKLTKEAEKKAKTLENELNSLKKELSKKSDELEKGLKKLAQEKSSVEQQL 902 Query: 1229 DQRGFEIAELWKQHLAQ-READFQ------KTEH-------------ELRVQLSAFESKY 1268 +Q ++ EL K H Q +E D + EH +++ ++ E K Sbjct: 903 EQLRKQMIELEKSHQVQLKEKDEKLVDTEASNEHLMDKLRSAGNAIQKMKAEMEKIEQKR 962 Query: 1269 EQLLDSVQSSTQEETNKIVTME----QVTSLQNKLQDKEEHLRNL-QEKYA--DVINQIE 1321 ++L + V +S +VT E ++++L K ++ + +L +EK A + I +E Sbjct: 963 KELDEQVAASKASVDAFLVTEEKYKTEISTLTKKTDEQTSEIESLKEEKKALDEKILNVE 1022 Query: 1322 ILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSS 1381 ++++ E +L + S K+ E L+ +E L K Sbjct: 1023 NNLTKVKAENEILTEKSEEEKNKLKKQVEELEAKISSLKEDHESKSLSGVQEKELLTKEL 1082 Query: 1382 XXXXXXXXXXXXRVNDAEAKVLELTHQLE----LKDS----------EIYQKTHEYTITL 1427 V+ E++VLE + +LE L DS E+ +K E+ TL Sbjct: 1083 QVAKEQLKKLQKEVSTKESQVLEKSKELEEATKLSDSKATALQSEVDEMRKKLDEHESTL 1142 Query: 1428 TQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHE-NANHYETMQ-----KESE 1481 + E + Q+ E + ++E+L ESEL I + K+ E A +T + K +E Sbjct: 1143 KTKEVELKEKTSQITEVQAKVEEL----ESELLIAKTKLEEAEATSLKTTEELKETKSAE 1198 Query: 1482 IERVKLIEELNVKITESVSLNKQ-VAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEI 1540 K + +L ++ E S N AE+ + E++ A T+ E + L + I Sbjct: 1199 NSARKQVAQLENEVKELKSKNADFAAEIEQLKEQKTALELHKTTSSEKHASSVAELEEAI 1258 Query: 1541 TNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKE 1579 + + ++ + ++K S +K ++ ++ E Sbjct: 1259 SKAKLQIKKNLDTLKKKDEEVSKSKAIAEKHVETISRHE 1297 >UniRef50_A0DAF7 Cluster: Chromosome undetermined scaffold_43, whole genome shotgun sequence; n=2; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_43, whole genome shotgun sequence - Paramecium tetraurelia Length = 2374 Score = 132 bits (320), Expect = 6e-29 Identities = 273/1304 (20%), Positives = 560/1304 (42%), Gaps = 101/1304 (7%) Query: 325 TKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKS 384 T+ I+ L+ N ++ QT E +N+L E KA + + L ++K ++ S+ + Sbjct: 249 TEAIQELKKQN-ELLQTQLEDQNQLQQENDELKA-NKLQLQDQLLQAQKQLQDLLSE-QI 305 Query: 385 PWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXG 444 P SS ++ TD + +I++L+ Q+LN+ + + + E D Sbjct: 306 PKQVTSSGSIQFQTDPQ-KALQISQLQQTNQALNQQIEELQQQRKE-DLQKFQDMIGNGV 363 Query: 445 KDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKD-VNVKDLIE 503 + I L E QQ ++ +++I + Q L+ +L + K +++ D ++ Sbjct: 364 NEQQIVALMSEKQQLQSDLRMLQ-----SKLDQIQQEQLALQSQLTQKTKQLIDIHDDVK 418 Query: 504 KLKSAEEQITQLNDEIDAANKNMIKVKSNHK--LKLKQMQKTIDNFS-KVSDSNKEIVRL 560 + + ++Q QL++E + K + KVKS ++ L+L+ T + K+ K+I L Sbjct: 419 QEEQIQQQ-QQLSNENELLKKQLEKVKSQYQELLELQSQNLTPNGLQEKLLQQTKQIHDL 477 Query: 561 TEELHHLSQKV-AELEEEKGNL---QLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAI 616 E+ H L ++ E+ + G L + L D + + +D Y +++ + + + + Sbjct: 478 EEQNHILQHQIETEIPQLVGELTETKQKLKDAITDAQLWNDKYHDLLDHKQSVQPQHQEE 537 Query: 617 SLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKK 676 + + K + Q L LQQ+Y ++ L + Q Q + +E +L + D L S + Sbjct: 538 DIAKMTKEEAQQALSDLQQQY---QNSLLKLKQAQDN---AEENKQNLIKAQDNLDNSSR 591 Query: 677 ELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELL 736 + L LK KE L ++L+N D+ K Q Q+ +DL ++LE+ +AE Sbjct: 592 DAKL----LKEQKEILEKQTENLQNVNNDLKQKDQENRQQILDLRNQLEQENAEFWRTEY 647 Query: 737 AKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLE 796 K+ ++ I TQF ++ + +I+ E ++ + + E + + + L+ Sbjct: 648 QKLANKHGEDIPTQFPSSKQVVPQ--HIQKDEGNQTEAIQELKKQNELLQTQLEDQNQLQ 705 Query: 797 RKADQL-GSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKN 855 ++ D+L + LQ + + +D L ++ + ++ Q + +L N Sbjct: 706 QENDELKANKLQLQDQLLQAQKQLQDLLSEQIPKQVTSSGSIQFQTDPQKALVDQLIIIN 765 Query: 856 QILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEH- 914 Q+ ++ I++ ++ + ++ + L SE + Q+ LR L+S L +I E Sbjct: 766 QLSIKLINRRIITIK--KRRFIEVLRYDWKWTLM-SEKQQLQSDLRMLQSKLDQIQQEQL 822 Query: 915 --QTLIVQKKKEIEDLEIEFNTQIESAIRDKKVL---NEKYEKNIEYVTQLEAQLQEYKN 969 Q+ + QK K++ ++I + + E I+ ++ L NE +K +E V +L E ++ Sbjct: 823 ALQSQLTQKTKQL--IDIHDDVKQEEQIQQQQQLSNENELLKKQLEKVKSQYQELLELQS 880 Query: 970 NIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTE--QYINEINKLNALLKQKDEEIIA 1027 N E+L + ++ D Q Q TE Q + E+ + LK + Sbjct: 881 QNLTPNGLQEKLLQQTKQIHDLEEQNHILQHQIETEIPQLVGELTETKQKLKDAITDAQL 940 Query: 1028 LNQKINNAQVSYMSMVSDY-ESKLAQFTTK-----LENMEEEMQRVSKQLLDSKQHNEE- 1080 N K ++ S+ + E +A+ T + L +++++ Q +L ++ + EE Sbjct: 941 WNDKYHDLLDHKQSVQPQHQEEDIAKMTKEEAQQALSDLQQQYQNSLLKLKQAQDNAEEN 1000 Query: 1081 LQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXX 1140 Q L++ QD+ ++ KL K + I+ E + + N++ Sbjct: 1001 KQNLIKAQDNLDNSSRDAKLL------KEQKEILEKQTENLQNVNNDLKQKDQENRQQIL 1054 Query: 1141 XLKVQEEEEFIQ-ERSVLQEQSAKLNTELQECY---TKIIQLETLNTELTGHDVVNQ--E 1194 LK Q E+E + R+ Q+ + K ++ + +++ E + + + + Sbjct: 1055 DLKNQLEQENAEFWRTEYQKLANKHGEDIPTQFPSSKQVVPQHIQKDEGNQTEAIQELKK 1114 Query: 1195 QINQLKSKLE---QLNTENDNLLSTVAELRSSISSAVDQRGFEIAE-LWKQHLAQREADF 1250 Q L+++LE QL END L + +L+ + A Q ++E + KQ + F Sbjct: 1115 QNELLQTQLEDQNQLQQENDELKANKLQLQDQLLQAQKQLQDLLSEQIPKQVTSSGSIQF 1174 Query: 1251 QKTEHELRVQLSAFESKYE---QLLDSVQSSTQEETNKI-------VTMEQVTSLQNKLQ 1300 Q T+ + +Q+S + + Q ++ +Q +E+ K V +Q+ +L ++ Q Sbjct: 1175 Q-TDPQKALQISQLQQTNQALNQQIEELQQQRKEDLQKFQDMIGNGVNEQQIVALMSEKQ 1233 Query: 1301 DKEEHLRNLQEKYADVINQIEILRSEI-EDEKVAFXXXXXXXXXXXXXXXXDLRTENQSY 1359 + LR LQ K V + L+S++ + K L EN+ Sbjct: 1234 QLQSDLRMLQSKLDQVQQEQLALQSQLTQKTKQLIDIHDDVKQEEQIQQQQQLSNENELL 1293 Query: 1360 KQMQEQSILNINEENAQLKKSSXX---XXXXXXXXXXRVNDAEAKVLELTHQLELKDSEI 1416 K+ Q + + + +E +L+ + +++D E + L HQ+E +EI Sbjct: 1294 KK-QLEKVKSQYQELLELQSQNLTPNGLQEKLLQQTKQIHDLEEQNHILQHQIE---TEI 1349 Query: 1417 YQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETM 1476 Q E T T + D + + +Y + + D ++ L K+ + N + Sbjct: 1350 PQLVGELTQTKQKLKDAITDAQLWNDKYHQLLGDHQQASPQQILDLEQKLTDAQNE---V 1406 Query: 1477 QKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQE-IEIVT 1535 QKE E + L +E +++ S + K L E V + NE++ LE QE I Sbjct: 1407 QKEKE-KYNHLFQEQYSQLSPSSAQAK--------LLEAVNQINELKAQLEAQEKARIAN 1457 Query: 1536 LNDEITNL-QNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNK 1578 L ++ +L + ++ QK V + + +Q++ N+ Sbjct: 1458 LIEKEPSLAMDKLQEDLLNYQKQVEMQEKLNEIQLQQIEFLRNQ 1501 Score = 108 bits (259), Expect = 1e-21 Identities = 219/1056 (20%), Positives = 449/1056 (42%), Gaps = 66/1056 (6%) Query: 560 LTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIES--DVYKKMIEMENLAET-RLKAI 616 L EE+ ++ + + EEE +LQ H ++ D +M+ +V ++ + E+ A + K Sbjct: 30 LKEEILQETKLIHQQEEEIQSLQ-HQIEQDLPQMVGKLEEVQLRLKQAEDEANLWKSKHQ 88 Query: 617 SLLESQ---KFDLVQELHILQQKYDEVEDKLAD--ISQLQSDQVCSEIKSVHLEEQ--ID 669 LLE++ + V + I + ++ + + D I Q Q++Q E ++ +E+Q + Sbjct: 89 MLLENRPNIQQPTVDKQSIKELNLEQAQQAVQDLLIKQEQNEQHKDEQQNKIMEQQNQLQ 148 Query: 670 ALSASKKELALVIENLKLDKEQLYGTIKDLENDK-EDIMNKLQNYIQENMDLTDKLEKMS 728 L K L NL L++ Q+ DL+ + E++ N+ Q+ +DL ++LE+ + Sbjct: 149 QLQDEKDNLQRE-NNLLLEQNQIVKQQNDLQKKQVEELKNQDLENRQQILDLKNQLEQEN 207 Query: 729 AEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVM 788 AE K+ ++ I TQF ++ + +I+ E ++ + + E + Sbjct: 208 AEFWRTEYQKLANKHGEDIPTQFPSSKQVVPQ--HIQKDEGNQTEAIQELKKQNELLQTQ 265 Query: 789 EDRRYSLERKADQL-GSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQL-LEIEH 846 + + L+++ D+L + LQ + + +D L ++ + ++ Q + Sbjct: 266 LEDQNQLQQENDELKANKLQLQDQLLQAQKQLQDLLSEQIPKQVTSSGSIQFQTDPQKAL 325 Query: 847 ENKELQKKNQILLEENQNLQIS-LSDMQQHYNALVEKANRTDLAE--SESTKYQTQLRDL 903 + +LQ+ NQ L ++ + LQ D+Q+ + + N + SE + Q+ LR L Sbjct: 326 QISQLQQTNQALNQQIEELQQQRKEDLQKFQDMIGNGVNEQQIVALMSEKQQLQSDLRML 385 Query: 904 ESNLKRITHEH---QTLIVQKKKEIEDLEIEFNTQIESAIRDKKVL---NEKYEKNIEYV 957 +S L +I E Q+ + QK K++ ++I + + E I+ ++ L NE +K +E V Sbjct: 386 QSKLDQIQQEQLALQSQLTQKTKQL--IDIHDDVKQEEQIQQQQQLSNENELLKKQLEKV 443 Query: 958 TQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTE--QYINEINKLN 1015 +L E ++ N E+L + ++ D Q Q TE Q + E+ + Sbjct: 444 KSQYQELLELQSQNLTPNGLQEKLLQQTKQIHDLEEQNHILQHQIETEIPQLVGELTETK 503 Query: 1016 ALLKQKDEEIIALNQKINNAQVSYMSMVSDY-ESKLAQFTTK-----LENMEEEMQRVSK 1069 LK + N K ++ S+ + E +A+ T + L +++++ Q Sbjct: 504 QKLKDAITDAQLWNDKYHDLLDHKQSVQPQHQEEDIAKMTKEEAQQALSDLQQQYQNSLL 563 Query: 1070 QLLDSKQHNEE-LQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNV 1128 +L ++ + EE Q L++ QD+ ++ KL K + I+ E + + N++ Sbjct: 564 KLKQAQDNAEENKQNLIKAQDNLDNSSRDAKLL------KEQKEILEKQTENLQNVNNDL 617 Query: 1129 DXXXXXXXXXXXXLKVQEEEEFIQ-ERSVLQEQSAKLNTELQECYTKIIQLETLNTELTG 1187 L+ Q E+E + R+ Q+ + K ++ + Q+ + + Sbjct: 618 KQKDQENRQQILDLRNQLEQENAEFWRTEYQKLANKHGEDIPTQFPSSKQVVPQHIQ--- 674 Query: 1188 HDVVNQ-EQINQLKSKLEQLNT--ENDNLLSTV-AELRSSISSAVDQRGFEIAELWKQHL 1243 D NQ E I +LK + E L T E+ N L EL+++ DQ A+ Q L Sbjct: 675 KDEGNQTEAIQELKKQNELLQTQLEDQNQLQQENDELKANKLQLQDQ--LLQAQKQLQDL 732 Query: 1244 AQREADFQKTEH-ELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDK 1302 + Q T ++ Q ++ +QL+ Q S + +I+T+++ ++ D Sbjct: 733 LSEQIPKQVTSSGSIQFQTDPQKALVDQLIIINQLSIKLINRRIITIKKRRFIEVLRYDW 792 Query: 1303 EEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQM 1362 + L + +++ + ++ +I+ E++A D++ E Q +Q Sbjct: 793 KWTLMSEKQQLQSDLRMLQSKLDQIQQEQLALQSQLTQKTKQLIDIHDDVKQEEQIQQQQ 852 Query: 1363 QEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHE 1422 Q + + ++ + KS N + K+L+ T Q+ + + + H+ Sbjct: 853 QLSNENELLKKQLEKVKSQYQELLELQSQNLTPNGLQEKLLQQTKQIHDLEEQNHILQHQ 912 Query: 1423 YTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHY-ETMQKESE 1481 + Q E +Q+L + I D + +L K H E + K ++ Sbjct: 913 IETEIPQLVGELTETKQKL---KDAITDAQLWNDKYHDLLDHKQSVQPQHQEEDIAKMTK 969 Query: 1482 IERVKLIEELNVKITESVSLNKQV---AELNK--ALEEEVAKTNEMQTA-LENQEIEIVT 1535 E + + +L + S+ KQ AE NK ++ + N + A L ++ EI Sbjct: 970 EEAQQALSDLQQQYQNSLLKLKQAQDNAEENKQNLIKAQDNLDNSSRDAKLLKEQKEI-- 1027 Query: 1536 LNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQ 1571 L + NLQN+ K Q++ D K +++ Sbjct: 1028 LEKQTENLQNVNNDLKQKDQENRQQILDLKNQLEQE 1063 Score = 101 bits (243), Expect = 1e-19 Identities = 219/1088 (20%), Positives = 463/1088 (42%), Gaps = 109/1088 (10%) Query: 430 EKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQEL 489 +KD K + Q QLE Q ++ + + +++ + Q+QL+ L Sbjct: 1099 QKDEGNQTEAIQELKKQNELLQTQLEDQNQLQQENDELKANKLQLQDQLLQAQKQLQDLL 1158 Query: 490 NDEI-KDVNVKDLIEKLKSAEE--QITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDN 546 +++I K V I+ ++ QI+QL A N+ + +++ K L++ Q I N Sbjct: 1159 SEQIPKQVTSSGSIQFQTDPQKALQISQLQQTNQALNQQIEELQQQRKEDLQKFQDMIGN 1218 Query: 547 FSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEME 606 + ++IV L E L + L+ + +Q + ++S + +K ++ Sbjct: 1219 ----GVNEQQIVALMSEKQQLQSDLRMLQSKLDQVQQEQL------ALQSQLTQKTKQLI 1268 Query: 607 NLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEE 666 ++ + +K ++ Q+ L E +L+++ ++V+ + ++ +LQS + L + Sbjct: 1269 DIHDD-VKQEEQIQQQQ-QLSNENELLKKQLEKVKSQYQELLELQSQNLTPNGLQEKLLQ 1326 Query: 667 QIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEK 726 Q + +++ ++ ++ + QL G + + +D + Q + + L ++ Sbjct: 1327 QTKQIHDLEEQNHILQHQIETEIPQLVGELTQTKQKLKDAITDAQLWNDKYHQLLGDHQQ 1386 Query: 727 MSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIA 786 S ++I +L K+ + Q+++Q + K + L+ E S+LS ++ +L E++ Sbjct: 1387 ASPQQILDLEQKLT-DAQNEVQKE-----KEKYNHLFQEQY-SQLSPSSAQ-AKLLEAVN 1438 Query: 787 VMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEH 846 + + + LE + + L EK+ + + +QED L + V M +++ E QL +IE Sbjct: 1439 QINELKAQLEAQEKARIANLIEKEPSLAMDKLQEDLLNYQKQVEMQ-EKLNEIQLQQIEF 1497 Query: 847 ENKEL---QKKNQILLE-ENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRD 902 +L +K QI + E++ Q SL D A + + + +L +++T Q Q Sbjct: 1498 LRNQLAQRDQKQQIKQDQEDEETQQSLRDQNIILQAQLAQKQK-ELDNAQATLIQNQQII 1556 Query: 903 LESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQ-LE 961 E +++ E KK+ DL +Q A + K++L +K + + + Q + Sbjct: 1557 DEQQQEQLKSEFW------KKQYTDLI----SQQAPADQQKQILKQKESELTQEIKQPSQ 1606 Query: 962 AQLQEYKNNIENLNMNVEELNKMNLEL---IDKHVQK-QQTQSPDYTEQYINEINKLNAL 1017 + + I NL + L + ++ + K Q + T SP + +I KLN Sbjct: 1607 SNNDNLQEQINNLLIERASLQQQLIQAQGKLGKATQNLESTDSPQQGQDSQGQIQKLN-- 1664 Query: 1018 LKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQH 1077 ++ +E+ NQ + S +S D KLAQ K N + + SK ++D + Sbjct: 1665 --REVQELQQRNQNLIEQMKSALSG-DDQGQKLAQLIEK--NNQLSLNN-SKLMIDLDVN 1718 Query: 1078 NEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXX 1137 +EL +++Q +++ K + ++ + + +S + + VD Sbjct: 1719 QKEL---LKQQGQNQVLIEKVKDLSDPSVTENAKLRVSDLQKQIDLIGQQVDFWKQKYQQ 1775 Query: 1138 XXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQIN 1197 Q IQ + + Q Q QE ++Q T T+L N+ QIN Sbjct: 1776 VLNEYSQQLSPTSIQRKMLEQAQYI----HQQEEALLMLQQTTDQTKLD-----NENQIN 1826 Query: 1198 QLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHEL 1257 QL+ + + LN EN NL + E + + ++ +QH+ ++ + K Sbjct: 1827 QLRIENKILNDENVNLKKRIQEQEN-----------QSQQISRQHVLSQD-QYDK----- 1869 Query: 1258 RVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKE-EHLRNLQEKYADV 1316 Q+ ++ KY++ L ++ Q+ + + +Q S QN DK+ + + Q++ +++ Sbjct: 1870 --QIQFWKEKYQEALQALHKDPQKVQD--IIQQQEESAQNIQSDKDWQPILKQQDQSSEI 1925 Query: 1317 INQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQ 1376 I+++ + E V F +L + Q Q+ +I + + +Q Sbjct: 1926 IDKLRSENQTFQGE-VTF----------YKKRVFELEQQQQKPDPSQQDTIQSQQYQISQ 1974 Query: 1377 LKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFEN 1436 L + + ND V++ + E+ Q T Y Q+ D+ E Sbjct: 1975 LDRDLQKALQTSAYWEQKYND----VVQQSINKEVGQRGDAQNTASY---WRQKFDQAEQ 2027 Query: 1437 VRQQLVE-YEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKI 1495 RQQL++ +++ E + +S +IL+ ++ E T + E ++++L + N Sbjct: 2028 SRQQLMQVIQEKEEQIEQHMQSFQSILKDELKEEL----TKIRNQERQKIELQLQQNQPY 2083 Query: 1496 TESVSLNK 1503 ES + K Sbjct: 2084 NESNLIQK 2091 Score = 99.5 bits (237), Expect = 7e-19 Identities = 222/1174 (18%), Positives = 483/1174 (41%), Gaps = 100/1174 (8%) Query: 237 QRLLKDIESKDVRISSLEEANKLLEAA---RFEISLEHSKL-AQELEQXXXXXXXXXXXX 292 Q + KD ++ I L++ N+LL+ + ++ E+ +L A +L+ Sbjct: 1096 QHIQKDEGNQTEAIQELKKQNELLQTQLEDQNQLQQENDELKANKLQLQDQLLQAQKQLQ 1155 Query: 293 XXLAKQ---SIEPSCEEKTEIEEKGSLEIANMTELTKKI-ELLEHLNCQIRQTNKELENK 348 L++Q + S + + + + +L+I+ + + + + + +E L Q ++ ++ ++ Sbjct: 1156 DLLSEQIPKQVTSSGSIQFQTDPQKALQISQLQQTNQALNQQIEELQQQRKEDLQKFQDM 1215 Query: 349 LATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIA 408 + E + V+ S+K + ++ +++ L S+ L Q T + I+ ++ Sbjct: 1216 IGNGVNEQQIVALMSEKQQLQSDLRMLQSKLDQVQQEQLALQSQ-LTQKTKQLIDIHDDV 1274 Query: 409 KLEMVIQ-----SLNKDLVDK--EYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQH-M 460 K E IQ S +L+ K E V S+ LQ Q H + Sbjct: 1275 KQEEQIQQQQQLSNENELLKKQLEKVKSQYQELLELQSQNLTPNGLQEKLLQQTKQIHDL 1334 Query: 461 EGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNV-KDLIEKLKSAEEQITQLNDEI 519 E + I ++ ++ Q KQ+L D I D + D +L +Q + + Sbjct: 1335 EEQNHILQHQIETEIPQLVGELTQTKQKLKDAITDAQLWNDKYHQLLGDHQQASP-QQIL 1393 Query: 520 DAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKG 579 D K K K K + +S++S S+ + +L E ++ +++ A+LE ++ Sbjct: 1394 DLEQKLTDAQNEVQKEKEKYNHLFQEQYSQLSPSSAQ-AKLLEAVNQINELKAQLEAQEK 1452 Query: 580 NLQLHLVDYDSGRM---IESDV--YKKMIEM-ENLAETRLKAISLLESQKFDLVQELHIL 633 +L++ + ++ D+ Y+K +EM E L E +L+ I L +Q Q+ I Sbjct: 1453 ARIANLIEKEPSLAMDKLQEDLLNYQKQVEMQEKLNEIQLQQIEFLRNQLAQRDQKQQIK 1512 Query: 634 QQKYDE-VEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQL 692 Q + DE + L D + + Q+ + K + + A +++ + +L E Sbjct: 1513 QDQEDEETQQSLRDQNIILQAQLAQKQKEL---DNAQATLIQNQQIIDEQQQEQLKSEFW 1569 Query: 693 YGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHE--EQSKIQTQ 750 DL + + + Q Q+ +LT ++++ S L +IN+ E++ +Q Q Sbjct: 1570 KKQYTDLISQQAPADQQKQILKQKESELTQEIKQPSQSNNDNLQEQINNLLIERASLQQQ 1629 Query: 751 F-GIDAKIQERDLYIENIESELSKYKSR--ICRLEESIAVMEDRRYSLERKADQLGSYLQ 807 K+ + +E+ +S S+ I +L + ++ R +L + S Sbjct: 1630 LIQAQGKLGKATQNLESTDSPQQGQDSQGQIQKLNREVQELQQRNQNLIEQMKSALSGDD 1689 Query: 808 EKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEEN--QNL 865 + QK +N +++D D V +K+LL+ + +N+ L +K + L + + +N Sbjct: 1690 QGQKLAQLIEKNNQLSLNNSKLMIDLD-VNQKELLKQQGQNQVLIEKVKDLSDPSVTENA 1748 Query: 866 QISLSDMQQHYNALVEKANR-TDLAESESTKYQTQLRDLESNLKRIT-----HEHQTLIV 919 ++ +SD+Q+ + + ++ + + +Y QL K + H+ + ++ Sbjct: 1749 KLRVSDLQKQIDLIGQQVDFWKQKYQQVLNEYSQQLSPTSIQRKMLEQAQYIHQQEEALL 1808 Query: 920 QKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKN----NIENLN 975 ++ + +++ QI + K+LN++ + + + E Q Q+ + + + Sbjct: 1809 MLQQTTDQTKLDNENQINQLRIENKILNDENVNLKKRIQEQENQSQQISRQHVLSQDQYD 1868 Query: 976 MNVE---ELNKMNLELIDKHVQKQQT--QSPDYTEQYINEINKLNALLKQKDEEIIALNQ 1030 ++ E + L+ + K QK Q Q + + Q I +LKQ+D+ ++ Sbjct: 1869 KQIQFWKEKYQEALQALHKDPQKVQDIIQQQEESAQNIQSDKDWQPILKQQDQSSEIID- 1927 Query: 1031 KINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDD 1090 K+ + ++ V+ Y+ ++ + LE +++ + + S+Q+ + + D Sbjct: 1928 KLRSENQTFQGEVTFYKKRVFE----LEQQQQKPDPSQQDTIQSQQYQ------ISQLDR 1977 Query: 1091 QIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLK-----VQ 1145 +++ +T +E I+ + D N + +Q Sbjct: 1978 DLQKALQTSAYWEQKYNDVVQQSINKEVGQRGDAQNTASYWRQKFDQAEQSRQQLMQVIQ 2037 Query: 1146 EEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELT------------------G 1187 E+EE I++ +Q + L EL+E TKI E EL Sbjct: 2038 EKEEQIEQH--MQSFQSILKDELKEELTKIRNQERQKIELQLQQNQPYNESNLIQKLKEQ 2095 Query: 1188 HDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLA-QR 1246 H+V Q+ I + +++QL N + I QR E+ EL +QHL + Sbjct: 2096 HEVEKQQLIQEFLRRIDQLLQSNVQKYPEGENWKELILRYEKQRQNELYEL-RQHLEILQ 2154 Query: 1247 EADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEET-------NKIVT--MEQVTSLQN 1297 + Q + E + A+E+ +L + +Q +E K++ +QV LQN Sbjct: 2155 RSQIQTKDIEFYAERRAYENAINELKNRIQQDDPQELYDTIEYQRKVILDLEDQVGFLQN 2214 Query: 1298 KLQDKEEHLRNLQEKYADVINQIEILRSEIEDEK 1331 + + E H+ L ++ + + I + + ++ K Sbjct: 2215 ERNNLEMHIMQLNQQIDQLKDNISRYQMQSDNRK 2248 Score = 96.3 bits (229), Expect = 6e-18 Identities = 181/889 (20%), Positives = 378/889 (42%), Gaps = 117/889 (13%) Query: 738 KINHEEQSKIQT-QFGID-------AKIQERDLYIENIESELSKYKSRICRLEESIAVME 789 K+ H+++ +IQ+ Q I+ K++E L ++ E E + +KS+ L E+ ++ Sbjct: 39 KLIHQQEEEIQSLQHQIEQDLPQMVGKLEEVQLRLKQAEDEANLWKSKHQMLLENRPNIQ 98 Query: 790 DRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENK 849 ++ +L L++ Q+A + I++++ + + QL +++ E Sbjct: 99 QPTVD-KQSIKELN--LEQAQQAVQDLLIKQEQNEQHKDEQQNKIMEQQNQLQQLQDEKD 155 Query: 850 ELQKKNQILLEENQ--NLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNL 907 LQ++N +LLE+NQ Q L Q + NR + + ++ Q + Sbjct: 156 NLQRENNLLLEQNQIVKQQNDLQKKQVEELKNQDLENRQQILDLKNQLEQENAEFWRTEY 215 Query: 908 KRITHEH----QTLIVQKKKEI-EDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEA 962 +++ ++H T K+ + + ++ + Q E AI++ K NE + +E QL+ Sbjct: 216 QKLANKHGEDIPTQFPSSKQVVPQHIQKDEGNQTE-AIQELKKQNELLQTQLEDQNQLQQ 274 Query: 963 QLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKD 1022 + E K N L + + K +L+ + + KQ T S Q+ + K + Q Sbjct: 275 ENDELKANKLQLQDQLLQAQKQLQDLLSEQIPKQVTSSGSI--QFQTDPQKA-LQISQLQ 331 Query: 1023 EEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQ 1082 + ALNQ+I Q + L +F + N E Q V+ L+ KQ +LQ Sbjct: 332 QTNQALNQQIEELQ-------QQRKEDLQKFQDMIGNGVNEQQIVA--LMSEKQ---QLQ 379 Query: 1083 ILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXL 1142 +R ++ ++++ +L + + + +I + DD + Sbjct: 380 SDLRMLQSKLDQIQQEQLALQSQLTQKTKQLID-----IHDDVKQEE------------- 421 Query: 1143 KVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTG--HDVVNQ-EQINQL 1199 ++Q++++ E +L++Q K+ ++ QE +++L++ N G ++ Q +QI+ L Sbjct: 422 QIQQQQQLSNENELLKKQLEKVKSQYQE----LLELQSQNLTPNGLQEKLLQQTKQIHDL 477 Query: 1200 KSK----LEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELW----------KQHL-- 1243 + + Q+ TE L+ + E + + A+ A+LW KQ + Sbjct: 478 EEQNHILQHQIETEIPQLVGELTETKQKLKDAITD-----AQLWNDKYHDLLDHKQSVQP 532 Query: 1244 AQREADFQK-TEHELRVQLSAFESKYE-QLLDSVQSSTQEETNKIVTMEQVTSLQNKLQD 1301 +E D K T+ E + LS + +Y+ LL Q+ E NK + + Q+ L + Sbjct: 533 QHQEEDIAKMTKEEAQQALSDLQQQYQNSLLKLKQAQDNAEENK----QNLIKAQDNLDN 588 Query: 1302 KEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQ 1361 + L+E+ + Q E L++ D K L EN + + Sbjct: 589 SSRDAKLLKEQKEILEKQTENLQNVNNDLK----QKDQENRQQILDLRNQLEQENAEFWR 644 Query: 1362 MQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTH 1421 + Q + N + E+ + S N EA + EL Q EL +++ + Sbjct: 645 TEYQKLANKHGEDIPTQFPSSKQVVPQHIQKDEGNQTEA-IQELKKQNELLQTQLEDQNQ 703 Query: 1422 EYTITLTQRNDEFE----NVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQ 1477 L Q NDE + ++ QL++ +K+++DL E+ I + + ++T Sbjct: 704 -----LQQENDELKANKLQLQDQLLQAQKQLQDLLSEQ-----IPKQVTSSGSIQFQTDP 753 Query: 1478 KESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTAL-ENQEI--EIV 1534 +++ ++++ +I +L++K+ +N+++ + K EV + + T + E Q++ ++ Sbjct: 754 QKALVDQLIIINQLSIKL-----INRRIITIKKRRFIEVLRYDWKWTLMSEKQQLQSDLR 808 Query: 1535 TLNDEITNLQNMVRASSS----KIQKHVSFASDTKQGRDEQLDNTMNKE 1579 L ++ +Q A S K ++ + D KQ Q ++ E Sbjct: 809 MLQSKLDQIQQEQLALQSQLTQKTKQLIDIHDDVKQEEQIQQQQQLSNE 857 Score = 68.1 bits (159), Expect = 2e-09 Identities = 165/854 (19%), Positives = 365/854 (42%), Gaps = 94/854 (11%) Query: 334 LNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSET 393 L Q+ Q KEL+N AT+ + + ++ + + K ++ L S+ Sbjct: 1531 LQAQLAQKQKELDNAQATLIQNQQIIDEQQQE----------QLKSEFWKKQYTDLISQQ 1580 Query: 394 LNQDTDKKINKNEIAKLEMVI----QSLNKDLVDK-EYVISEKDT--XXXXXXXXXXGKD 446 D K+I K + ++L I QS N +L ++ ++ E+ + GK Sbjct: 1581 APADQQKQILKQKESELTQEIKQPSQSNNDNLQEQINNLLIERASLQQQLIQAQGKLGKA 1640 Query: 447 TLIAQLQLEHQQHMEGPSLIH-VGTNTEDVNE-IAKVQEQLKQELNDEIKDVNVKDLIEK 504 T + QQ + I + +++ + + EQ+K L+ + + + LIEK Sbjct: 1641 TQNLESTDSPQQGQDSQGQIQKLNREVQELQQRNQNLIEQMKSALSGDDQGQKLAQLIEK 1700 Query: 505 LKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTID-----NFS-KVSDSNKEIV 558 ++L ++D K ++K + +++ +++++ D N +VSD K+I Sbjct: 1701 NNQLSLNNSKLMIDLDVNQKELLKQQGQNQVLIEKVKDLSDPSVTENAKLRVSDLQKQID 1760 Query: 559 RLTEELHHLSQK----VAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRL- 613 + +++ QK + E ++ + + + I ++ + +T+L Sbjct: 1761 LIGQQVDFWKQKYQQVLNEYSQQLSPTSIQRKMLEQAQYIHQQEEALLMLQQTTDQTKLD 1820 Query: 614 --KAISLLESQKFDLVQELHILQQKYDEVEDKLADISQ---LQSDQVCSEIK--SVHLEE 666 I+ L + L E L+++ E E++ IS+ L DQ +I+ +E Sbjct: 1821 NENQINQLRIENKILNDENVNLKKRIQEQENQSQQISRQHVLSQDQYDKQIQFWKEKYQE 1880 Query: 667 QIDALSASKKELALVI-------ENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMD 719 + AL +++ +I +N++ DK+ + I ++ +I++KL++ EN Sbjct: 1881 ALQALHKDPQKVQDIIQQQEESAQNIQSDKD--WQPILKQQDQSSEIIDKLRS---ENQT 1935 Query: 720 LTDKLE--KMSAEKISELLAKINHEEQSKIQTQ----FGIDAKIQE--------RDLYIE 765 ++ K ++ + K + +Q IQ+Q +D +Q+ Y + Sbjct: 1936 FQGEVTFYKKRVFELEQQQQKPDPSQQDTIQSQQYQISQLDRDLQKALQTSAYWEQKYND 1995 Query: 766 NIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEY-----TIQE 820 ++ ++K + + + + + E+ QL +QEK++ ++ +I + Sbjct: 1996 VVQQSINKEVGQRGDAQNTASYWRQKFDQAEQSRQQLMQVIQEKEEQIEQHMQSFQSILK 2055 Query: 821 DELVNRLAVLMDHDR-VVEKQLLEIE--HENKELQK-KNQILLEENQNLQISLSDMQQHY 876 DEL L + + +R +E QL + + +E+ +QK K Q +E+ Q +Q L + Q Sbjct: 2056 DELKEELTKIRNQERQKIELQLQQNQPYNESNLIQKLKEQHEVEKQQLIQEFLRRIDQLL 2115 Query: 877 NALVEK----ANRTDLAESESTKYQTQLRDLESNLKRITHEH-QTLIVQKKKEIEDLEIE 931 + V+K N +L + Q +L +L +L+ + QT ++ E E Sbjct: 2116 QSNVQKYPEGENWKELILRYEKQRQNELYELRQHLEILQRSQIQTKDIEFYAERRAYENA 2175 Query: 932 FNTQIESAIR--DKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELI 989 N ++++ I+ D + L + E + + LE Q+ +N NL M++ +LN+ ++ + Sbjct: 2176 IN-ELKNRIQQDDPQELYDTIEYQRKVILDLEDQVGFLQNERNNLEMHIMQLNQ-QIDQL 2233 Query: 990 DKHVQKQQTQSPDYTEQYINEINKLNALLKQK---DEEIIALNQKINNAQ--VSYMSMVS 1044 ++ + Q QS + Q + + + +++ E + ++++ +Q S+ Sbjct: 2234 KDNISRYQMQSDNRKRQRAEVLEAIEEMKRERARERESYKSPHRQMRQSQNRSSWDRYPK 2293 Query: 1045 DY-ESKLAQFTTKLENMEEEMQRV---SKQLLDSKQHNEELQILVREQDDQIKELKETKL 1100 DY Q ++ + MQR+ Q + +Q N ++ +L ++ D++K + L Sbjct: 2294 DYLRPSNIQQPSQFQEHSSPMQRIPFQQSQFVSPQQENRDI-VLKLQELDEVKHKYQNAL 2352 Query: 1101 TFEMNIPKTEGMII 1114 NI + E +I Sbjct: 2353 N---NILQLEAQVI 2363 Score = 58.4 bits (135), Expect = 2e-06 Identities = 112/593 (18%), Positives = 250/593 (42%), Gaps = 58/593 (9%) Query: 394 LNQDTD--KKINKNEIAKLEMVIQSLNKDLVD-KEYVISEKDTXXXXXXXXXXGKDTLIA 450 L Q TD K N+N+I +L + + LN + V+ K+ + +++ +D Sbjct: 1810 LQQTTDQTKLDNENQINQLRIENKILNDENVNLKKRIQEQENQSQQISRQHVLSQDQYDK 1869 Query: 451 QLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEE 510 Q+Q +++ E +H + + V +I + QE+ Q + D + + ++++ + E Sbjct: 1870 QIQFWKEKYQEALQALH--KDPQKVQDIIQQQEESAQNIQS---DKDWQPILKQQDQSSE 1924 Query: 511 QITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSK--VSDSNKEIVRLTEELHHLS 568 I +L E + + + +L+Q Q+ D + + +I +L +L Sbjct: 1925 IIDKLRSE-NQTFQGEVTFYKKRVFELEQQQQKPDPSQQDTIQSQQYQISQLDRDLQKAL 1983 Query: 569 QKVAELEEEKGNLQLHLVDYDSGRMIESD---VYKKMIEMENLAETRLKAISLLESQKFD 625 Q A E++ ++ ++ + G+ ++ Y + + + ++R + + +++ ++ Sbjct: 1984 QTSAYWEQKYNDVVQQSINKEVGQRGDAQNTASYWRQ-KFDQAEQSRQQLMQVIQEKEEQ 2042 Query: 626 LVQELHILQQKY-DEVEDKLADIS---------QLQSDQVCSEIKSVH-LEEQIDALSAS 674 + Q + Q DE++++L I QLQ +Q +E + L+EQ + Sbjct: 2043 IEQHMQSFQSILKDELKEELTKIRNQERQKIELQLQQNQPYNESNLIQKLKEQHEVEKQQ 2102 Query: 675 K-KELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKIS 733 +E I+ L Q Y + EN KE I+ + E +L LE + +I Sbjct: 2103 LIQEFLRRIDQLLQSNVQKY---PEGENWKELILRYEKQRQNELYELRQHLEILQRSQIQ 2159 Query: 734 ELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRY 793 + E ++ + +IQ+ D + + + + I LE+ + +++ R Sbjct: 2160 TKDIEFYAERRAYENAINELKNRIQQDDP--QELYDTIEYQRKVILDLEDQVGFLQNERN 2217 Query: 794 SLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQK 853 +LE QL + + + S Y +Q D NR ++Q E+ +E+++ Sbjct: 2218 NLEMHIMQLNQQIDQLKDNISRYQMQSD---NR-----------KRQRAEVLEAIEEMKR 2263 Query: 854 KNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHE 913 + E ++ + M+Q N D + + +Q ++ S ++RI + Sbjct: 2264 ER---ARERESYKSPHRQMRQSQNRSSWDRYPKDYLRPSNIQQPSQFQEHSSPMQRIPFQ 2320 Query: 914 HQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQE 966 Q+ V ++E D+ ++ +++ + KY+ + + QLEAQ+ E Sbjct: 2321 -QSQFVSPQQENRDIVLK--------LQELDEVKHKYQNALNNILQLEAQVIE 2364 Score = 39.5 bits (88), Expect = 0.75 Identities = 93/454 (20%), Positives = 188/454 (41%), Gaps = 49/454 (10%) Query: 453 QLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIK-DVNVKDLIEKLKSAEEQ 511 +LE QQ PS T +I+++ L++ L + D++++ S ++ Sbjct: 1949 ELEQQQQKPDPS--QQDTIQSQQYQISQLDRDLQKALQTSAYWEQKYNDVVQQ--SINKE 2004 Query: 512 ITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVR-LTEELHHLSQK 570 + Q D + A+ K + + + MQ + ++ + L +EL K Sbjct: 2005 VGQRGDAQNTASYWRQKFDQAEQSRQQLMQVIQEKEEQIEQHMQSFQSILKDELKEELTK 2064 Query: 571 VAELEEEKGNLQLHLVD-YDSGRMIESDVYKKMIEMENLAETRLKAIS-LLES--QKFDL 626 + E +K LQL Y+ +I+ + +E + L + L+ I LL+S QK+ Sbjct: 2065 IRNQERQKIELQLQQNQPYNESNLIQKLKEQHEVEKQQLIQEFLRRIDQLLQSNVQKYPE 2124 Query: 627 VQELHILQQKYDEV-EDKLADISQ----LQSDQVCSEIKSVHLEEQIDALSASKKELALV 681 + L +Y++ +++L ++ Q LQ Q+ + K + + A + EL Sbjct: 2125 GENWKELILRYEKQRQNELYELRQHLEILQRSQI--QTKDIEFYAERRAYENAINELKNR 2182 Query: 682 IENLKLDKEQLYGTIK-------DLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISE 734 I+ + D ++LY TI+ DLE+ + N+ N M L +++++ + IS Sbjct: 2183 IQ--QDDPQELYDTIEYQRKVILDLEDQVGFLQNERNNLEMHIMQLNQQIDQLK-DNISR 2239 Query: 735 LLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYS 794 + ++ ++ + + I+ +ER E YKS ++ +S R S Sbjct: 2240 YQMQSDNRKRQRAEVLEAIEEMKRER-------ARERESYKSPHRQMRQS-----QNRSS 2287 Query: 795 LERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKK 854 +R YL+ IQ+ + M + Q + + EN+++ K Sbjct: 2288 WDRYPKD---YLRPSN-------IQQPSQFQEHSSPMQRIPFQQSQFVSPQQENRDIVLK 2337 Query: 855 NQILLEENQNLQISLSDMQQHYNALVEKANRTDL 888 Q L E Q +L+++ Q ++EK + D+ Sbjct: 2338 LQELDEVKHKYQNALNNILQLEAQVIEKLQQDDI 2371 >UniRef50_Q6CPF6 Cluster: Kluyveromyces lactis strain NRRL Y-1140 chromosome E of strain NRRL Y- 1140 of Kluyveromyces lactis; n=1; Kluyveromyces lactis|Rep: Kluyveromyces lactis strain NRRL Y-1140 chromosome E of strain NRRL Y- 1140 of Kluyveromyces lactis - Kluyveromyces lactis (Yeast) (Candida sphaerica) Length = 1755 Score = 132 bits (320), Expect = 6e-29 Identities = 217/1058 (20%), Positives = 469/1058 (44%), Gaps = 91/1058 (8%) Query: 529 VKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNL-QLHL-- 585 VK N K + + TI+N + ++ N ++ +L++ L HL + E E L + H Sbjct: 701 VKFN-KTRADLEKSTIENENVINSLNSKLEKLSKSLEHLETEKVNAETELNQLNERHSAL 759 Query: 586 -VDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEV-EDK 643 V+ + ++ V K ++E L + KAI++ + Q ++++ LQQK E+ E K Sbjct: 760 EVELNDTKIALESVNNKSQKLEELKQKNTKAIAVNQEQIDKYKEKINGLQQKVKEISESK 819 Query: 644 LA---DISQLQSDQVCSEIKSVHLEEQIDA----LSASKKELALVIENLKLDKEQLYGTI 696 L I+++ + ++ L+E + + L +K+ + NL+ ++ + Sbjct: 820 LKAEDGINKMSRELFTLTKENGKLKEDLKSHSKKLEIQEKKYSSETANLEKQLKERGTEV 879 Query: 697 KDL-ENDKEDI--MNKLQNYI----QENMDLTDKLEKMSA--EKISELLAKINHEEQSKI 747 ++L E EDI ++ L+ + + ++L KL ++ K++E L + + + Sbjct: 880 QELRERISEDIKRIDTLEKNVTILSNQKIELETKLSNQTSLIPKLTEKLKGLANNYKDLE 939 Query: 748 QTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQ 807 + + KI E++ + I L+ + + E + + D +Y+ E + ++ Sbjct: 940 NERDTLAKKILEKEEANKTIMQNLNSEIESLNKEREEMRL--DLQYAAEYHQKEKENFDA 997 Query: 808 EKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQI 867 QK SE + + +++ L +D E+Q+ E + N+EL+ L + L+ Sbjct: 998 HTQKLTSENNSKSESIIS-LQTKLDE---CERQIKEYKTTNEELKNSLHALNVKCIELES 1053 Query: 868 SLSDMQQ---HYNALVEKANRTDLAESESTKYQTQLRDLESNLK---RITHE---HQTLI 918 SL +Q + + +E+ N + +A ++ + Q+ L + + LK +I E +Q + Sbjct: 1054 SLESAKQSTDNSDETIEELNDSVIAIND--ELQSVLAEKDELLKQNNKINEELCNYQQEL 1111 Query: 919 VQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNV 978 +K + L+ + ++ ++ + N+K + + A++++ K+ I N+ N Sbjct: 1112 QEKADSCQGLQDKISSLNNEIMQISEESNDKIKLLEASNEEKVAEIKDLKSEISNIKQNA 1171 Query: 979 E---ELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNA 1035 + E K ++ + + ++ + Y N + L + K++ + ++ A Sbjct: 1172 DTKAEKLKSEIDALKSRISDLESLLETKNKLYENSQTTITELEQAKEKLQRTIQEQYKEA 1231 Query: 1036 QVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKEL 1095 Q S S+++ E+K+ ++LE + ++ VSK+ ++ +EE++ + E +D +K L Sbjct: 1232 QYSEDSLLAG-ENKIKHLESQLEKL--KLSSVSKE-KEAHLKDEEIKSVKAEIEDNVK-L 1286 Query: 1096 KETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERS 1155 + K T E++ K + +++S + + A + ++F +ER Sbjct: 1287 VQAKST-ELDELKKQNSVLNSKLNKEKEKAKIEQHKLRESLATARDELKSKIKDFEEERK 1345 Query: 1156 VLQEQSAKLNTELQECYTKIIQL-ETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLL 1214 +L E S++LN + E KI++L ETLN H+ Q+ N +++ LEQ E+ + L Sbjct: 1346 LLSEGSSELNQQYSE---KILKLEETLNNVKADHEKAVQKLENTIEA-LEQQAEESKSSL 1401 Query: 1215 STVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDS 1274 T S+SS Q+ ++ ++ A+ QK +L +L+ + +++ ++ Sbjct: 1402 DT----ERSLSSKEQQQRLQLEKIL--------ANEQKENKDLENKLADLDQLFKEHENT 1449 Query: 1275 VQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAF 1334 ++S T+ + +E+ + + +L+ E L++ + I + EIL S++ DE V Sbjct: 1450 LESQTKISQDYKQQLEKNSQVIEELKSAESALKDKLIAAEEKIKESEILTSQL-DEAVTS 1508 Query: 1335 XXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXR 1394 DL +N K E IL +E ++ ++S Sbjct: 1509 TSALLEEQTKLKKSISDLEAKN--IKDCGEMEIL--RKELSKCQESLKVSQRLNEEKDEA 1564 Query: 1395 VNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYE 1454 E ++ L ++ E+ K E + FE +++++ K +E Sbjct: 1565 NKRTETDIVSLQKEINTLKEELRTKNDEISC--------FEADKKEMIAKLKELE----- 1611 Query: 1455 KESELAILRLKMHENANH-YETMQKESEIERVKL-IEELNVKITESVSL-NKQVAELNKA 1511 ES+ ++ +NA E EI+ +KL + K+ S L + + EL K Sbjct: 1612 -ESKTLLVHSAQEKNAQMIQENTSLAEEIKELKLQVNTWTEKLVTSEQLWSSEKTELIKQ 1670 Query: 1512 LEEEVAKTNEMQTALENQE--IEIVTLNDEITNLQNMV 1547 + ++ KT + A EN + +E+ + +E L+N V Sbjct: 1671 M--DIIKTESAKQAQENSQLNVELSAIKEENMKLKNRV 1706 Score = 127 bits (306), Expect = 3e-27 Identities = 226/1095 (20%), Positives = 463/1095 (42%), Gaps = 97/1095 (8%) Query: 147 LSNTIKEKDNALSVLQVKMKIMETTILDLQ-EKINEKDQIIEAKNKATTXXXXXXXXXXX 205 L + E +N ++ L K++ + ++ L+ EK+N + ++ + + + Sbjct: 710 LEKSTIENENVINSLNSKLEKLSKSLEHLETEKVNAETELNQLNERHSALEVELNDTKIA 769 Query: 206 XXXXXXEDTK-QQMTKMQENFIAMEAEWKDEKQRLLKDIESK--DVRISSLEEANKLLEA 262 + K +++ + IA+ E D+ + + ++ K ++ S L+ + + + Sbjct: 770 LESVNNKSQKLEELKQKNTKAIAVNQEQIDKYKEKINGLQQKVKEISESKLKAEDGINKM 829 Query: 263 AR--FEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIAN 320 +R F ++ E+ KL ++L+ + E TE++E Sbjct: 830 SRELFTLTKENGKLKEDLKSHSKKLEIQEKKYSSETANLEKQLKERGTEVQELRE----R 885 Query: 321 MTELTKKIELLEHLNCQIRQTNK-ELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTA 379 ++E K+I+ LE N I K ELE KL+ ++ + ++K K N Sbjct: 886 ISEDIKRIDTLEK-NVTILSNQKIELETKLSN---QTSLIPKLTEK------LKGLANNY 935 Query: 380 SKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXX 439 +++ L+ + L ++ + NK + L I+SLNK+ +E + + Sbjct: 936 KDLENERDTLAKKILEKE---EANKTIMQNLNSEIESLNKE---REEMRLDLQYAAEYHQ 989 Query: 440 XXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVK 499 D +L E+ E S+I + T ++ K + +EL + + +NVK Sbjct: 990 KEKENFDAHTQKLTSENNSKSE--SIISLQTKLDECERQIKEYKTTNEELKNSLHALNVK 1047 Query: 500 --DLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEI 557 +L L+SA++ ++ I+ N ++I + + L + + + +K+ N+E+ Sbjct: 1048 CIELESSLESAKQSTDNSDETIEELNDSVIAINDELQSVLAEKDELLKQNNKI---NEEL 1104 Query: 558 VRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAIS 617 +EL + L+++ +L ++ ES+ K++E N E ++ I Sbjct: 1105 CNYQQELQEKADSCQGLQDKISSLNNEIMQISE----ESNDKIKLLEASN--EEKVAEIK 1158 Query: 618 LLESQKFDLVQELHILQQKY-DEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKK 676 L+S+ ++ Q +K E++ + IS L+S + + I L +K+ Sbjct: 1159 DLKSEISNIKQNADTKAEKLKSEIDALKSRISDLESLLETKNKLYENSQTTITELEQAKE 1218 Query: 677 ELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELL 736 +L I+ + + ++ EN + + ++L+ ++ +K + E+I + Sbjct: 1219 KLQRTIQEQYKEAQYSEDSLLAGENKIKHLESQLEKLKLSSVS-KEKEAHLKDEEIKSVK 1277 Query: 737 AKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYS-- 794 A+I + +D ++ + + E K K +L ES+A D S Sbjct: 1278 AEIEDNVKLVQAKSTELDELKKQNSVLNSKLNKEKEKAKIEQHKLRESLATARDELKSKI 1337 Query: 795 --LERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQ 852 E + L E + YSE ++ +E +N V DH++ V+K IE ++ + Sbjct: 1338 KDFEEERKLLSEGSSELNQQYSEKILKLEETLNN--VKADHEKAVQKLENTIEALEQQAE 1395 Query: 853 KKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLK--RI 910 + L E SLS +Q +EK + + E+ + +L DL+ K Sbjct: 1396 ESKSSLDTER-----SLSSKEQQQRLQLEKILANE--QKENKDLENKLADLDQLFKEHEN 1448 Query: 911 THEHQTLIVQK-KKEIE--DLEIEFNTQIESAIRDKKVLNEKYEKNIEYVT-QLEAQLQE 966 T E QT I Q K+++E IE ESA++DK + E+ K E +T QL+ + Sbjct: 1449 TLESQTKISQDYKQQLEKNSQVIEELKSAESALKDKLIAAEEKIKESEILTSQLDEAVTS 1508 Query: 967 YKNNIE---NLNMNVEELNKMN------LELIDKHVQKQQTQSPDYTEQYINEINKLNAL 1017 +E L ++ +L N +E++ K + K Q +S +++ E ++ N Sbjct: 1509 TSALLEEQTKLKKSISDLEAKNIKDCGEMEILRKELSKCQ-ESLKVSQRLNEEKDEAN-- 1565 Query: 1018 LKQKDEEIIALNQKINNAQVSYMSM---VSDYESKLAQFTTKLENMEEEMQRVSKQLLDS 1074 K+ + +I++L ++IN + + +S +E+ + KL+ +EE SK LL Sbjct: 1566 -KRTETDIVSLQKEINTLKEELRTKNDEISCFEADKKEMIAKLKELEE-----SKTLLVH 1619 Query: 1075 KQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXX 1134 + Q +++E +E+KE KL ++N TE ++ S + S + + Sbjct: 1620 SAQEKNAQ-MIQENTSLAEEIKELKL--QVN-TWTEKLVTSEQL--WSSEKTEL-IKQMD 1672 Query: 1135 XXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQE 1194 + QE + E S ++E++ KL + + +++ L L T+L E Sbjct: 1673 IIKTESAKQAQENSQLNVELSAIKEENMKLKNRVDD-RSEVDDLVILVTDL-------DE 1724 Query: 1195 QINQLKSKLEQLNTE 1209 Q ++ K KL +L E Sbjct: 1725 QKSKYKRKLIELGVE 1739 Score = 121 bits (292), Expect = 1e-25 Identities = 203/1027 (19%), Positives = 427/1027 (41%), Gaps = 91/1027 (8%) Query: 627 VQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLK 686 ++ +++ ++E + L++++V +E + L E+ AL + + +E++ Sbjct: 715 IENENVINSLNSKLEKLSKSLEHLETEKVNAETELNQLNERHSALEVELNDTKIALESVN 774 Query: 687 LDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSK 746 ++L E++ K I N + DK + EKI+ L K+ +SK Sbjct: 775 NKSQKL-----------EELKQKNTKAIAVNQEQIDKYK----EKINGLQQKVKEISESK 819 Query: 747 IQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYL 806 ++ + GI+ R+L+ + E K K + + + + E ++YS E L L Sbjct: 820 LKAEDGINK--MSRELF--TLTKENGKLKEDLKSHSKKLEIQE-KKYSSETA--NLEKQL 872 Query: 807 QEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQ 866 +E+ E + E + R+ L + ++ Q +E+E + L E+ + L Sbjct: 873 KERGTEVQELRERISEDIKRIDTLEKNVTILSNQKIELETKLSNQTSLIPKLTEKLKGLA 932 Query: 867 ISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQT--LIVQKKKE 924 + D++ + L +K L + E+ K T +++L S ++ + E + L +Q E Sbjct: 933 NNYKDLENERDTLAKKI----LEKEEANK--TIMQNLNSEIESLNKEREEMRLDLQYAAE 986 Query: 925 IEDLEIE-FNTQIESAIRDKKVLNEKYEKNIEYVTQL---EAQLQEYKNNIENLNMNVEE 980 E E F+ + + N K E I T+L E Q++EYK E L ++ Sbjct: 987 YHQKEKENFDAHTQKLTSEN---NSKSESIISLQTKLDECERQIKEYKTTNEELKNSLHA 1043 Query: 981 LNKMNLELIDK-HVQKQQTQSPDYTEQYINE----IN-KLNALLKQKDEEIIALNQKINN 1034 LN +EL KQ T + D T + +N+ IN +L ++L +KDE ++ N KIN Sbjct: 1044 LNVKCIELESSLESAKQSTDNSDETIEELNDSVIAINDELQSVLAEKDE-LLKQNNKINE 1102 Query: 1035 AQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDS----KQHNEELQILVREQDD 1090 +Y + + K+ ++ E+ ++S++ D + NEE +++ Sbjct: 1103 ELCNYQQELQEKADSCQGLQDKISSLNNEIMQISEESNDKIKLLEASNEEKVAEIKDLKS 1162 Query: 1091 QIKELKET------KLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLK- 1143 +I +K+ KL E++ K+ + S +E + N L+ Sbjct: 1163 EISNIKQNADTKAEKLKSEIDALKSRISDLESLLETKNKLYENSQTTITELEQAKEKLQR 1222 Query: 1144 -VQEEEEFIQ--ERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLK 1200 +QE+ + Q E S+L ++ + E Q + ++L +++ E H + E+I +K Sbjct: 1223 TIQEQYKEAQYSEDSLLAGENKIKHLESQ---LEKLKLSSVSKEKEAH--LKDEEIKSVK 1277 Query: 1201 SKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQ 1260 +++E N + ST + +S ++ + + E K + EL+ + Sbjct: 1278 AEIED-NVKLVQAKSTELDELKKQNSVLNSKLNKEKEKAKIEQHKLRESLATARDELKSK 1336 Query: 1261 LSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQI 1320 + FE + + L + Q+ + KI+ +E+ +L N D E+ ++ L+ + Q Sbjct: 1337 IKDFEEERKLLSEGSSELNQQYSEKILKLEE--TLNNVKADHEKAVQKLENTIEALEQQA 1394 Query: 1321 EILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSIL-----NINEENA 1375 E +S ++ E+ + + ++ + L N E Sbjct: 1395 EESKSSLDTERSLSSKEQQQRLQLEKILANEQKENKDLENKLADLDQLFKEHENTLESQT 1454 Query: 1376 QLKKSSXXXXXXXXXXXXRVNDAEAKVLE--LTHQLELKDSEIYQKTHEYTITLTQRN-D 1432 ++ + + AE+ + + + + ++K+SEI + +T T + Sbjct: 1455 KISQDYKQQLEKNSQVIEELKSAESALKDKLIAAEEKIKESEILTSQLDEAVTSTSALLE 1514 Query: 1433 EFENVRQQLVEYE-KRIEDL----TYEKESELAILRLKMHENANHY-ETMQKESEIERVK 1486 E +++ + + E K I+D KE LK+ + N + K +E + V Sbjct: 1515 EQTKLKKSISDLEAKNIKDCGEMEILRKELSKCQESLKVSQRLNEEKDEANKRTETDIVS 1574 Query: 1487 LIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQ---TAL------ENQEI--EIVT 1535 L +E+N E + N +++ +E +AK E++ T L +N ++ E + Sbjct: 1575 LQKEINTLKEELRTKNDEISCFEADKKEMIAKLKELEESKTLLVHSAQEKNAQMIQENTS 1634 Query: 1536 LNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDLAMYM 1595 L +EI L+ V + K+ S K +Q+D + A ++L++ + Sbjct: 1635 LAEEIKELKLQVNTWTEKLVTSEQLWSSEKTELIKQMDIIKTESAKQAQENSQLNVELSA 1694 Query: 1596 LHQRDVR 1602 + + +++ Sbjct: 1695 IKEENMK 1701 Score = 107 bits (258), Expect = 2e-21 Identities = 204/1060 (19%), Positives = 444/1060 (41%), Gaps = 94/1060 (8%) Query: 464 SLIHVGT---NTE-DVNEIAKVQEQLKQELND-EIKDVNVKDLIEKLKSAEEQITQLNDE 518 SL H+ T N E ++N++ + L+ ELND +I +V + +KL E++ Q N + Sbjct: 734 SLEHLETEKVNAETELNQLNERHSALEVELNDTKIALESVNNKSQKL----EELKQKNTK 789 Query: 519 IDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEK 578 A N+ I +K K+ +Q+ KV + ++ ++ + ++ +S+++ L +E Sbjct: 790 AIAVNQEQI---DKYKEKINGLQQ------KVKEISESKLKAEDGINKMSRELFTLTKEN 840 Query: 579 GNLQLHLVDYDSGRMIESDVYK-KMIEMENLAETRLKAISLLESQKFDLVQELHILQQKY 637 G L+ L + I+ Y + +E + R + L + + ++ + L++ Sbjct: 841 GKLKEDLKSHSKKLEIQEKKYSSETANLEKQLKERGTEVQELRERISEDIKRIDTLEKNV 900 Query: 638 DEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLK---LDKEQLYG 694 + ++ ++ S+Q K L E++ L+ + K+L + L L+KE+ Sbjct: 901 TILSNQKIELETKLSNQTSLIPK---LTEKLKGLANNYKDLENERDTLAKKILEKEEANK 957 Query: 695 TIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGID 754 TI N + + +NK + ++ ++ + + E K+ E SK ++ + Sbjct: 958 TIMQNLNSEIESLNKEREEMRLDLQYAAEYHQKEKENFDAHTQKLTSENNSKSESIISLQ 1017 Query: 755 AKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYS 814 K+ E + I+ ++ + K+ + L +E S ++ D ++E + Sbjct: 1018 TKLDECERQIKEYKTTNEELKNSLHALNVKCIELESSLESAKQSTDNSDETIEELNDSVI 1077 Query: 815 EYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQ 874 DEL +VL + D ++ KQ +I E Q++ Q + Q LQ +S + Sbjct: 1078 AI---NDEL---QSVLAEKDELL-KQNNKINEELCNYQQELQEKADSCQGLQDKISSLNN 1130 Query: 875 HYNALVEKAN-RTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFN 933 + E++N + L E+ + + +++DL+S + I T + K EI+ L+ Sbjct: 1131 EIMQISEESNDKIKLLEASNEEKVAEIKDLKSEISNIKQNADTKAEKLKSEIDALKSRI- 1189 Query: 934 TQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQ-----EYK-------------NNIENLN 975 + +ES + K L E + I + Q + +LQ +YK N I++L Sbjct: 1190 SDLESLLETKNKLYENSQTTITELEQAKEKLQRTIQEQYKEAQYSEDSLLAGENKIKHLE 1249 Query: 976 MNVEEL------NKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALN 1029 +E+L + L D+ ++ + + D + + +L+ L KQ LN Sbjct: 1250 SQLEKLKLSSVSKEKEAHLKDEEIKSVKAEIEDNVKLVQAKSTELDELKKQNSVLNSKLN 1309 Query: 1030 QKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQD 1089 ++ A++ + + + +K+++ EEE + +S+ + Q E +IL E+ Sbjct: 1310 KEKEKAKIEQHKLRESLATARDELKSKIKDFEEERKLLSEGSSELNQQYSE-KILKLEE- 1367 Query: 1090 DQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEE 1149 L K E + K E +TIE + A L +E+++ Sbjct: 1368 ----TLNNVKADHEKAVQKLE-----NTIEALEQQAEE----SKSSLDTERSLSSKEQQQ 1414 Query: 1150 FIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQ-LKSKLEQLNT 1208 +Q +L + K N +L+ K+ L+ L E + + +Q +I+Q K +LE+ + Sbjct: 1415 RLQLEKILANEQ-KENKDLE---NKLADLDQLFKE-HENTLESQTKISQDYKQQLEKNSQ 1469 Query: 1209 ENDNLLSTVAELRSSISSAVDQ-RGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESK 1267 + L S + L+ + +A ++ + EI + + + +L+ +S E+K Sbjct: 1470 VIEELKSAESALKDKLIAAEEKIKESEILTSQLDEAVTSTSALLEEQTKLKKSISDLEAK 1529 Query: 1268 YEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEI 1327 + ++ ++E +K E + Q ++K+E + + + +I L+ E+ Sbjct: 1530 NIKDCGEME-ILRKELSK--CQESLKVSQRLNEEKDEANKRTETDIVSLQKEINTLKEEL 1586 Query: 1328 EDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXX 1387 + ++ QE++ I +EN L + Sbjct: 1587 RTKNDEISCFEADKKEMIAKLKELEESKTLLVHSAQEKNAQMI-QENTSLAEEIKELKLQ 1645 Query: 1388 XXXXXXRVNDAE----AKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVE 1443 ++ +E ++ EL Q+++ +E ++ E +Q N E ++++ ++ Sbjct: 1646 VNTWTEKLVTSEQLWSSEKTELIKQMDIIKTESAKQAQEN----SQLNVELSAIKEENMK 1701 Query: 1444 YEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIE 1483 + R++D + + +L IL + E + Y+ E +E Sbjct: 1702 LKNRVDDRS--EVDDLVILVTDLDEQKSKYKRKLIELGVE 1739 Score = 71.7 bits (168), Expect = 2e-10 Identities = 127/673 (18%), Positives = 283/673 (42%), Gaps = 55/673 (8%) Query: 143 DVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXX 202 ++ + ++EK ++ LQ K+ + I+ + E+ N+K +++EA N+ Sbjct: 1103 ELCNYQQELQEKADSCQGLQDKISSLNNEIMQISEESNDKIKLLEASNEEKV-------- 1154 Query: 203 XXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEA 262 +D K +++ +++N A+ K EK L +I++ RIS LE LLE Sbjct: 1155 ------AEIKDLKSEISNIKQN-----ADTKAEK--LKSEIDALKSRISDLE---SLLE- 1197 Query: 263 ARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEE-KGSLEIANM 321 + ++ ELEQ A+ S + + +I+ + LE + Sbjct: 1198 TKNKLYENSQTTITELEQAKEKLQRTIQEQYKEAQYSEDSLLAGENKIKHLESQLEKLKL 1257 Query: 322 TELTKKIELLEHL-NCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTAS 380 + ++K+ E HL + +I+ E+E+ + + +S + K+ S L S+ + + Sbjct: 1258 SSVSKEKE--AHLKDEEIKSVKAEIEDNVKLVQAKSTELDELKKQNSVLNSKLNKEKEKA 1315 Query: 381 KMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXX 440 K++ + S T + KI E + + S + E ++ ++T Sbjct: 1316 KIEQHKLRESLATARDELKSKIKDFEEERKLLSEGSSELNQQYSEKILKLEETLNNVKAD 1375 Query: 441 XXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQ-EQLKQELNDEIKDVNVK 499 L ++ QQ E S + + + ++Q E++ E KD+ K Sbjct: 1376 HEKAVQKLENTIEALEQQAEESKSSLDTERSLSSKEQQQRLQLEKILANEQKENKDLENK 1435 Query: 500 DL-IEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTI-DNFSKVSDSNKEI 557 +++L E + +I K ++ S +LK + + D + KE Sbjct: 1436 LADLDQLFKEHENTLESQTKISQDYKQQLEKNSQVIEELKSAESALKDKLIAAEEKIKES 1495 Query: 558 VRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMI---ESDVYKKMIE--------ME 606 LT +L + L EE+ L+ + D ++ + E ++ +K + + Sbjct: 1496 EILTSQLDEAVTSTSALLEEQTKLKKSISDLEAKNIKDCGEMEILRKELSKCQESLKVSQ 1555 Query: 607 NLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSD--QVCSEIKSVHL 664 L E + +A E+ L +E++ L+ +E+ K +IS ++D ++ +++K + Sbjct: 1556 RLNEEKDEANKRTETDIVSLQKEINTLK---EELRTKNDEISCFEADKKEMIAKLKELEE 1612 Query: 665 EEQIDALSASKKELALVIENLKLDKE--QL---YGTIKDLENDKEDIMNKLQNYIQENMD 719 + + SA +K ++ EN L +E +L T + E + + + + + MD Sbjct: 1613 SKTLLVHSAQEKNAQMIQENTSLAEEIKELKLQVNTWTEKLVTSEQLWSSEKTELIKQMD 1672 Query: 720 LTDKLEKMSAEKISELLAKIN--HEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSR 777 + A++ S+L +++ EE K++ + +++ + + + +++ + SKYK + Sbjct: 1673 IIKTESAKQAQENSQLNVELSAIKEENMKLKNRVDDRSEVDDLVILVTDLDEQKSKYKRK 1732 Query: 778 ICRLEESIAVMED 790 + L ++ E+ Sbjct: 1733 LIELGVELSSDEE 1745 Score = 54.4 bits (125), Expect = 2e-05 Identities = 67/379 (17%), Positives = 161/379 (42%), Gaps = 26/379 (6%) Query: 1195 QINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEI--AELWKQHLAQREADFQK 1252 + N+ ++ LE+ EN+N+++++ +S +++ E AE L +R + + Sbjct: 702 KFNKTRADLEKSTIENENVINSLNSKLEKLSKSLEHLETEKVNAETELNQLNERHSALEV 761 Query: 1253 TEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQE- 1311 ++ ++ L + +K ++L + Q +T+ V EQ+ + K+ ++ ++ + E Sbjct: 762 ELNDTKIALESVNNKSQKLEELKQKNTKAIA---VNQEQIDKYKEKINGLQQKVKEISES 818 Query: 1312 --KYADVINQI--EILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQS- 1366 K D IN++ E+ E+ K+ T N KQ++E+ Sbjct: 819 KLKAEDGINKMSRELFTLTKENGKLKEDLKSHSKKLEIQEKKYSSETANLE-KQLKERGT 877 Query: 1367 -ILNINEENAQ-------LKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQ 1418 + + E ++ L+K+ ++++ + + +LT +L+ + Y+ Sbjct: 878 EVQELRERISEDIKRIDTLEKNVTILSNQKIELETKLSNQTSLIPKLTEKLKGLANN-YK 936 Query: 1419 KTHEYTITLTQRNDEFENVRQQLVE-YEKRIEDLTYEKESELAILRLKMHENANHYETMQ 1477 TL ++ E E + +++ IE L E+E +RL + A +++ + Sbjct: 937 DLENERDTLAKKILEKEEANKTIMQNLNSEIESLNKEREE----MRLDLQYAAEYHQKEK 992 Query: 1478 KESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLN 1537 + + KL E N K +SL ++ E + ++E E++ +L ++ + L Sbjct: 993 ENFDAHTQKLTSENNSKSESIISLQTKLDECERQIKEYKTTNEELKNSLHALNVKCIELE 1052 Query: 1538 DEITNLQNMVRASSSKIQK 1556 + + + S I++ Sbjct: 1053 SSLESAKQSTDNSDETIEE 1071 Score = 46.4 bits (105), Expect = 0.007 Identities = 79/445 (17%), Positives = 174/445 (39%), Gaps = 38/445 (8%) Query: 1170 ECYTKI-IQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAV 1228 E Y K+ ++ +L + N+ IN L SKLE+L+ ++L + + ++ Sbjct: 694 ELYEKLYVKFNKTRADLEKSTIENENVINSLNSKLEKLSKSLEHLETEKVNAETELNQLN 753 Query: 1229 DQRGFEIAELWKQHLAQREAD--FQKTEHELRVQLSAFE------SKYEQLLDSVQSSTQ 1280 ++ EL +A + QK E + A KY++ ++ +Q + Sbjct: 754 ERHSALEVELNDTKIALESVNNKSQKLEELKQKNTKAIAVNQEQIDKYKEKINGLQQKVK 813 Query: 1281 E-ETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXX 1339 E +K+ + + + +L + L+E ++EI + E A Sbjct: 814 EISESKLKAEDGINKMSRELFTLTKENGKLKEDLKSHSKKLEIQEKKYSSE-TANLEKQL 872 Query: 1340 XXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAE 1399 + +E+ E+++ ++ + +L+ ++ Sbjct: 873 KERGTEVQELRERISEDIKRIDTLEKNVTILSNQKIELETKLSNQTSLIPKLTEKLKGLA 932 Query: 1400 AKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTY------ 1453 +L ++ + +I +K + N E E++ ++ E R+ DL Y Sbjct: 933 NNYKDLENERDTLAKKILEKEEANKTIMQNLNSEIESLNKE--REEMRL-DLQYAAEYHQ 989 Query: 1454 -EKESELAILRLKMHENANHYETM----QKESEIER-VKLIEELNVKITESV-SLNKQVA 1506 EKE+ A + EN + E++ K E ER +K + N ++ S+ +LN + Sbjct: 990 KEKENFDAHTQKLTSENNSKSESIISLQTKLDECERQIKEYKTTNEELKNSLHALNVKCI 1049 Query: 1507 ELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNL----------QNMVRASSSKIQK 1556 EL +LE T+ +E ++ +NDE+ ++ N + Q+ Sbjct: 1050 ELESSLESAKQSTDNSDETIEELNDSVIAINDELQSVLAEKDELLKQNNKINEELCNYQQ 1109 Query: 1557 HVSFASDTKQGRDEQLDNTMNKELL 1581 + +D+ QG +++ +++N E++ Sbjct: 1110 ELQEKADSCQGLQDKI-SSLNNEIM 1133 >UniRef50_UPI0000E48979 Cluster: PREDICTED: similar to kinesin-related protein; n=3; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to kinesin-related protein - Strongylocentrotus purpuratus Length = 2537 Score = 132 bits (319), Expect = 8e-29 Identities = 249/1291 (19%), Positives = 549/1291 (42%), Gaps = 114/1291 (8%) Query: 342 NKELENKLATMGTES--KAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLS-SETLNQDT 398 N +++++L +M T++ +A+++ K L ++ ++A++ + + ++ SE T Sbjct: 807 NADIKSRLGSMETDALTEAMTTLEKSHKELAVLQAALDSANQEREAFGEVHISENSQLRT 866 Query: 399 DKKINKNEIAKLEMVIQS-----LNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQ 453 + + E+ L+ + LN+ L E ++ K+TL + + Sbjct: 867 ELESASRELHSLKEQYEERDTTRLNEALATLEKQAADLTELQAALEISRGEKETLERRSE 926 Query: 454 LEHQQHMEG-PSLIHVGTNTEDVNEIAKVQEQLKQE---LNDEIKDVNVKDLIEKLKSAE 509 + + + ++ V E+ V E L +E L D ++++ KD+ + Sbjct: 927 EMPSSDLNDIKATLESSQQSDQVREMQVVLETLTEENAALKDRLEELQTKDVNQVQVEEP 986 Query: 510 EQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDS-NKEIVRLTEELHHLS 568 E+I + E++ ++ ++ ++ +TI + ++ + + + ++ +L EL Sbjct: 987 EEILVMRAELEMSSALCDALQEEKDQLQTKLDETIPDAAQATQTPHPDVDKLKGELMESL 1046 Query: 569 QKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEM-ENLAETRL----KAISLLESQK 623 L EEK L L + + +D +I+M E +AE R KA E Q+ Sbjct: 1047 TLCEALNEEKNQLHSKLEETRKEIEMRTDESSDIIKMKEEIAELRFVLLQKAEEYAELQQ 1106 Query: 624 FDLVQ-------------ELHILQQKYDEVEDKLADI-SQLQSDQVCSEIKSVHLEEQID 669 F + E++ LQ+ + + L DI +++ + SE + L+ Q+D Sbjct: 1107 FTRWEDKSLKEQESEYQCEINRLQEIMKQKDKDLRDIETKITAQLTQSENEKTDLDFQLD 1166 Query: 670 ALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSA 729 A K+ + L+ ++ Y +K+ E + + E + +LE A Sbjct: 1167 A---EKERNRSMTSELRQQLQEAYDRLKEKEGAEGASAEEGMELETEKRENVVELEVRLA 1223 Query: 730 EKISE---LLAKINHEEQSKIQTQFGIDAKIQERDLY----IENIESELSKYKSRICRLE 782 E + E L K + +E+ + + + +QE++ + +ES L+ I L+ Sbjct: 1224 EVLREMESLREKESQKEEMVTELETKLAGALQEKENVEEKKVHELESRLASILMEIEALK 1283 Query: 783 ESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELV---NRL-AVLMDHDRVVE 838 + V E++ LE K L + +QE E T++E ++V +RL VL + D E Sbjct: 1284 KEKTVREEKVCDLEAK---LANAVQEIDTLREEETLKEQKMVELESRLNMVLQEQDGEKE 1340 Query: 839 KQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQT 898 ++LLE+ + L ++ + L EE + +++++ + E+ DL E + ++ Sbjct: 1341 EKLLELSSKLANLLQETEELREEKNFKEERIAELESLLGSAPEED--VDLKEERVMELES 1398 Query: 899 QLRDL--------------ESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKK 944 L ++ + + + ++ K+ ED E Q+ S +++ + Sbjct: 1399 HLANVLEETDSLRKAEAWKDERISELESRLGEVVNDKESGAEDKATELEAQLASVLQEVE 1458 Query: 945 VLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYT 1004 L E+ E +++LE++L + + E + K + +L D +Q+ + T Sbjct: 1459 ALREEKNVKEEQISELESRLANVQQDKEGEEEG--RVVKQDSQLSDA-LQELDAMKEELT 1515 Query: 1005 EQYINEINKLNALLKQKDEEIIALNQK--INNAQV----SYMSMVS---DYESKLAQFTT 1055 + +I +L + L +EI L Q+ + AQ+ S +++VS E K+A+ + Sbjct: 1516 LRE-EKIAQLESWLTTGMQEIEVLRQEKDVREAQMTELESRLAIVSKEISEEGKVAELES 1574 Query: 1056 KLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIIS 1115 L N+ EM + ++ +K EL+ + +++ LKE K + I E + S Sbjct: 1575 HLTNVVGEMDSLREEKNLNKDKVAELESDLASVVQELEALKEEKNLKDEEISDLEARLTS 1634 Query: 1116 STIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKI 1175 + E +++ V+ ++EE+ E+ + + A+LN++ QE + Sbjct: 1635 ESQEKSAEEDKVVELESDLASVVQELEALKEEKNLKDEQ--ISDLEARLNSDSQEKSAEE 1692 Query: 1176 IQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGF-- 1233 ++ L + LTG V QE LE L E + + E++S ++ A + F Sbjct: 1693 EKVVELESHLTG---VLQE--------LEALKEEKNQKVGKFLEMQSHLNDARQELEFLN 1741 Query: 1234 EIAELWKQHLAQREADFQKTEHELRV----QLSAFESKYEQLLDSVQSSTQEETNKIVTM 1289 E L ++ +A+ ++ F E + +++ ESK +L +++ + + + M Sbjct: 1742 EDKNLREEQMAELKSRFANVSQEQDIFREEKVAEAESKLANVLQEIEALKEGKNLREQHM 1801 Query: 1290 EQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXX 1349 ++ ++ + +++ +R +EK ++ +++ + E++ KV Sbjct: 1802 AELEAMLAHVSQEQDTVR--EEKVLELESRLSCVLQEMDTLKVEETLKEAKATELETRHS 1859 Query: 1350 XDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQL 1409 L +++Q++ + I +E A+L+ ++ V E + E ++ Sbjct: 1860 EVL----NDMERLQDE-LTRIKDEKARLEAANYEIMSQMQKD---VVTMETQTEEDVAEV 1911 Query: 1410 ELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHEN 1469 E + +++ + LT ++ E V+ Q R+E+L E E ++ Sbjct: 1912 E-QSHDLHAAIEKLRKVLTSKDQEICEVKAQSSHEMGRLEELQQCLEEESREREERITAE 1970 Query: 1470 ANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQ 1529 + E + E VK EL I+E+ L +++ + +E +A+ E +AL Q Sbjct: 1971 LRNLEAEKTRLEAALVKAELELGDSISETCLLKEEM----EMMESRLAEGRE--SALGQQ 2024 Query: 1530 EIEIVTLNDEITNLQNMVRASSSKIQKHVSF 1560 + E+ L E+ + +N++ +I+K F Sbjct: 2025 QQEMEELMVELDSARNLLSQKEDEIEKLQEF 2055 Score = 116 bits (280), Expect = 4e-24 Identities = 235/1177 (19%), Positives = 491/1177 (41%), Gaps = 131/1177 (11%) Query: 476 NEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAE---EQITQLNDEIDAANKNMIKVKSN 532 + I++ Q + EL + N++ K + AE Q T + D ++AAN I+V N Sbjct: 609 SHISESQNKELMELQAALDSANLEKAELKSRMAEIQEGQQTGMQDALNAANLE-IEVLKN 667 Query: 533 H--KLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDS 590 H + + K++ + + +N E++ E+ Q E++ G+ L + S Sbjct: 668 HVSESQNKELMELQAALDTANLANAELMSRMAEIEKEQQ--TEIQAALGSANLENAELKS 725 Query: 591 GRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQL 650 ++ K+++E+++ T I +L++ VQ +++ + + D + L Sbjct: 726 --LMAEQQNKQLMELQDALNTANLEIEVLKNHMTQ-VQNEQLMETQ------AVLDAANL 776 Query: 651 QSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDK-EDIMNK 709 +++ E+KS HL D + EL ++ + + + +E D + M Sbjct: 777 ENE----ELKS-HLA---DVQNKQLMELQAALDLANAENADIKSRLGSMETDALTEAMTT 828 Query: 710 LQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQF--------GIDAKIQERD 761 L+ +E L L+ + E+ E +++ E S+++T+ + + +ERD Sbjct: 829 LEKSHKELAVLQAALDSANQER--EAFGEVHISENSQLRTELESASRELHSLKEQYEERD 886 Query: 762 LY-IENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQE 820 + + L K + + L+ ++ + + +LER+++++ S KA E + Q Sbjct: 887 TTRLNEALATLEKQAADLTELQAALEISRGEKETLERRSEEMPSSDLNDIKATLESSQQS 946 Query: 821 DELVNRLAVLMDHDRVVEKQLLEIEHENKELQKK--NQILLEENQNLQISLSDMQQHYNA 878 D+ V + V+++ + ++ ++ +ELQ K NQ+ +EE + + + ++++ +A Sbjct: 947 DQ-VREMQVVLE---TLTEENAALKDRLEELQTKDVNQVQVEEPEEILVMRAELEMS-SA 1001 Query: 879 LVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIES 938 L D + E + QT+L + + + T + + K E+ +E T E+ Sbjct: 1002 LC------DALQEEKDQLQTKLDETIPDAAQATQTPHPDVDKLKGEL----MESLTLCEA 1051 Query: 939 AIRDKKVLNEKYE---KNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQK 995 +K L+ K E K IE T + + + K I L + + + EL + + Sbjct: 1052 LNEEKNQLHSKLEETRKEIEMRTDESSDIIKMKEEIAELRFVLLQKAEEYAEL-QQFTRW 1110 Query: 996 QQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSY---------------- 1039 + + +Y EIN+L ++KQKD+++ + KI AQ++ Sbjct: 1111 EDKSLKEQESEYQCEINRLQEIMKQKDKDLRDIETKI-TAQLTQSENEKTDLDFQLDAEK 1169 Query: 1040 ---MSMVSDYESKLAQFTTKL---ENMEEEMQRVSKQLLDSKQHN-EELQILVREQDDQI 1092 SM S+ +L + +L E E +L K+ N EL++ + E ++ Sbjct: 1170 ERNRSMTSELRQQLQEAYDRLKEKEGAEGASAEEGMELETEKRENVVELEVRLAEVLREM 1229 Query: 1093 KELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQ 1152 + L+E + E + + E + + E + + V ++ ++E+ ++ Sbjct: 1230 ESLREKESQKEEMVTELETKLAGALQEKENVEEKKVHELESRLASILMEIEALKKEKTVR 1289 Query: 1153 ERSVLQEQSAKLNTELQECYT----------KIIQLET-LNTELTGHDVVNQEQINQLKS 1201 E V + AKL +QE T K+++LE+ LN L D +E++ +L S Sbjct: 1290 EEKVC-DLEAKLANAVQEIDTLREEETLKEQKMVELESRLNMVLQEQDGEKEEKLLELSS 1348 Query: 1202 KL-------EQLNTENDNLLSTVAELRSSISSA----VDQRGFEIAELWKQHLAQ--REA 1248 KL E+L E + +AEL S + SA VD + + EL + HLA E Sbjct: 1349 KLANLLQETEELREEKNFKEERIAELESLLGSAPEEDVDLKEERVMEL-ESHLANVLEET 1407 Query: 1249 D-FQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKI-----VTMEQVTSLQNKLQDK 1302 D +K E ++S ES+ ++++ +S +++ ++ +++V +L+ + K Sbjct: 1408 DSLRKAEAWKDERISELESRLGEVVNDKESGAEDKATELEAQLASVLQEVEALREEKNVK 1467 Query: 1303 EEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQM 1362 EE + L+ + A+V E E E V +L + Q+ Sbjct: 1468 EEQISELESRLANVQQDKE---GEEEGRVVKQDSQLSDALQELDAMKEELTLREEKIAQL 1524 Query: 1363 QEQSILNINE-----ENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIY 1417 + + E + ++++ + E KV EL L E+ Sbjct: 1525 ESWLTTGMQEIEVLRQEKDVREAQMTELESRLAIVSKEISEEGKVAELESHLTNVVGEMD 1584 Query: 1418 QKTHEYTIT---LTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYE 1474 E + + + + +V Q+L E K ++L E+ S+L + + E Sbjct: 1585 SLREEKNLNKDKVAELESDLASVVQEL-EALKEEKNLKDEEISDLEARLTSESQEKSAEE 1643 Query: 1475 TMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIV 1534 E E + +++EL E ++Q+++L L + ++ ++A E + +E+ Sbjct: 1644 DKVVELESDLASVVQELEALKEEKNLKDEQISDLEARLNSD----SQEKSAEEEKVVELE 1699 Query: 1535 T-LNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDE 1570 + L + L+ + + K+ K + S R E Sbjct: 1700 SHLTGVLQELEALKEEKNQKVGKFLEMQSHLNDARQE 1736 Score = 116 bits (278), Expect = 7e-24 Identities = 260/1331 (19%), Positives = 572/1331 (42%), Gaps = 163/1331 (12%) Query: 365 KGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDK 424 K S ++ R++ R + + L E L + NK E+ +L+ + S N + + Sbjct: 579 KESDVLERQA-REAEMQAALDSANLEKEELKSHISESQNK-ELMELQAALDSANLEKAEL 636 Query: 425 EYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGT--------NTEDVN 476 + ++E L ++ H + L+ + N E ++ Sbjct: 637 KSRMAEIQEGQQTGMQDALNAANLEIEVLKNHVSESQNKELMELQAALDTANLANAELMS 696 Query: 477 EIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAAN-KNM-IKVKSNH- 533 +A+++++ + E+ + N+++ K AE+Q QL + DA N N+ I+V NH Sbjct: 697 RMAEIEKEQQTEIQAALGSANLENAELKSLMAEQQNKQLMELQDALNTANLEIEVLKNHM 756 Query: 534 -KLKLKQMQKT--------IDN---FSKVSD-SNKEIVRLTEELHHLSQKVAELEEEKGN 580 +++ +Q+ +T ++N S ++D NK+++ L L + + A+++ G+ Sbjct: 757 TQVQNEQLMETQAVLDAANLENEELKSHLADVQNKQLMELQAALDLANAENADIKSRLGS 816 Query: 581 LQLHLV---------DYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELH 631 ++ + + ++++ + E E E + S L ++ +ELH Sbjct: 817 METDALTEAMTTLEKSHKELAVLQAALDSANQEREAFGEVHISENSQLRTELESASRELH 876 Query: 632 ILQQKYDE------------VEDKLADISQLQSDQVCSEIKSVHLEEQIDAL-SASKKEL 678 L+++Y+E +E + AD+++LQ+ S + LE + + + S+ ++ Sbjct: 877 SLKEQYEERDTTRLNEALATLEKQAADLTELQAALEISRGEKETLERRSEEMPSSDLNDI 936 Query: 679 ALVIENLKLDKE--QLYGTIKDLENDKEDIMNKLQ-----NYIQENMDLTDKLEKMSAE- 730 +E+ + + ++ ++ L + + ++L+ + Q ++ +++ M AE Sbjct: 937 KATLESSQQSDQVREMQVVLETLTEENAALKDRLEELQTKDVNQVQVEEPEEILVMRAEL 996 Query: 731 KISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICR---LEESI-- 785 ++S L EE+ ++QT+ +D I + + ++ K K + L E++ Sbjct: 997 EMSSALCDALQEEKDQLQTK--LDETIPDAAQATQTPHPDVDKLKGELMESLTLCEALNE 1054 Query: 786 ------AVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEK 839 + +E+ R +E + D+ ++ K++ +E + A L R +K Sbjct: 1055 EKNQLHSKLEETRKEIEMRTDESSDIIKMKEE-IAELRFVLLQKAEEYAELQQFTRWEDK 1113 Query: 840 QLLEIEHENK-ELQKKNQILLEENQNLQISLSDMQQHYNA-LVEKAN-RTDL-----AES 891 L E E E + E+ + +I+ +++++L+ D++ A L + N +TDL AE Sbjct: 1114 SLKEQESEYQCEINRLQEIMKQKDKDLR----DIETKITAQLTQSENEKTDLDFQLDAEK 1169 Query: 892 ESTKYQT-----QLRDLESNLKR-------ITHEHQTLIVQKKKEIEDLEIEFNTQIESA 939 E + T QL++ LK E L +K++ + +LE+ ++ Sbjct: 1170 ERNRSMTSELRQQLQEAYDRLKEKEGAEGASAEEGMELETEKRENVVELEV----RLAEV 1225 Query: 940 IRDKKVLNEKYEKNIEYVTQLEAQLQ---EYKNNIENLNMNVEELN----KMNLELIDKH 992 +R+ + L EK + E VT+LE +L + K N+E ++ E M +E + K Sbjct: 1226 LREMESLREKESQKEEMVTELETKLAGALQEKENVEEKKVHELESRLASILMEIEALKKE 1285 Query: 993 VQKQQTQSPDYTEQYINEINKLNALLKQ---KDEEIIALNQKINNAQVSYMSMVSDYESK 1049 ++ + D + N + +++ L ++ K+++++ L ++N + + E K Sbjct: 1286 KTVREEKVCDLEAKLANAVQEIDTLREEETLKEQKMVELESRLN---MVLQEQDGEKEEK 1342 Query: 1050 LAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILV---REQDDQIKE------------ 1094 L + ++KL N+ +E + + ++ ++ EL+ L+ E+D +KE Sbjct: 1343 LLELSSKLANLLQETEELREEKNFKEERIAELESLLGSAPEEDVDLKEERVMELESHLAN 1402 Query: 1095 -LKETKLTFEMNIPKTEGMI-ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQ 1152 L+ET + K E + + S + + +D + +QE E + Sbjct: 1403 VLEETDSLRKAEAWKDERISELESRLGEVVNDKESGAEDKATELEAQLASVLQEVEALRE 1462 Query: 1153 ERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDN 1212 E++V +EQ ++L + L +Q + E G V Q++ +L+ + E Sbjct: 1463 EKNVKEEQISELESRLAN-----VQQDKEGEE-EGRVVKQDSQLSDALQELDAMKEELTL 1516 Query: 1213 LLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLL 1272 +A+L S +++ G + E+ +Q REA Q TE E R+ + + E E + Sbjct: 1517 REEKIAQLESWLTT-----GMQEIEVLRQEKDVREA--QMTELESRLAIVSKEISEEGKV 1569 Query: 1273 DSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSE--IEDE 1330 ++S TN + M+ + +N +DK + L+ A V+ ++E L+ E ++DE Sbjct: 1570 AELESHL---TNVVGEMDSLREEKNLNKDK---VAELESDLASVVQELEALKEEKNLKDE 1623 Query: 1331 KVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXX 1390 +++ D E +S Q + + EE LK Sbjct: 1624 EISDLEARLTSESQEKSAEEDKVVELESDLASVVQELEALKEEK-NLKDEQISDLEARLN 1682 Query: 1391 XXXRVNDA-EAKVLELTHQLE--LKDSE-IYQKTHEYTITLTQRNDEFENVRQQLVEYEK 1446 + A E KV+EL L L++ E + ++ ++ + + RQ+L E+ Sbjct: 1683 SDSQEKSAEEEKVVELESHLTGVLQELEALKEEKNQKVGKFLEMQSHLNDARQEL-EFLN 1741 Query: 1447 RIEDLTYEKESELAILRLKMHENANHY-ETMQKESEIERVKLIEELNVKITESVSLNKQ- 1504 ++L E+ +EL + + + + E E+E + +++E+ + E +L +Q Sbjct: 1742 EDKNLREEQMAELKSRFANVSQEQDIFREEKVAEAESKLANVLQEIEA-LKEGKNLREQH 1800 Query: 1505 VAELNKAL----EEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQ-KHVS 1559 +AEL L +E+ E LE++ ++ D + + + A +++++ +H Sbjct: 1801 MAELEAMLAHVSQEQDTVREEKVLELESRLSCVLQEMDTLKVEETLKEAKATELETRHSE 1860 Query: 1560 FASDTKQGRDE 1570 +D ++ +DE Sbjct: 1861 VLNDMERLQDE 1871 Score = 107 bits (256), Expect = 3e-21 Identities = 253/1294 (19%), Positives = 542/1294 (41%), Gaps = 128/1294 (9%) Query: 143 DVTHLSNTIKEKDNALSVLQVKMKIM------ETTILDLQ---EKINEKDQIIEAKNKAT 193 ++ L +K+KD L ++ K+ E T LD Q EK + E + + Sbjct: 1125 EINRLQEIMKQKDKDLRDIETKITAQLTQSENEKTDLDFQLDAEKERNRSMTSELRQQLQ 1184 Query: 194 TXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAME---AEWKDEKQRLLKDIESKDVRI 250 E + + T+ +EN + +E AE E + L + K+ + Sbjct: 1185 EAYDRLKEKEGAEGASAEEGMELE-TEKRENVVELEVRLAEVLREMESLREKESQKEEMV 1243 Query: 251 SSLEE--ANKLLEAARFEISLEH---SKLAQELEQXXXXXXXXXXXXXXLA--KQSIEPS 303 + LE A L E E H S+LA L + + + + + Sbjct: 1244 TELETKLAGALQEKENVEEKKVHELESRLASILMEIEALKKEKTVREEKVCDLEAKLANA 1303 Query: 304 CEEKTEIEEKGSLEIANMTELTKKIEL-LEHLNCQIRQTNKELENKLATMGTESKAVSSP 362 +E + E+ +L+ M EL ++ + L+ + + + EL +KLA + E++ + Sbjct: 1304 VQEIDTLREEETLKEQKMVELESRLNMVLQEQDGEKEEKLLELSSKLANLLQETEELREE 1363 Query: 363 SK-KGSPLISRKSGRNTASK-----MKSPWSQLSSETLN--QDTDKKINKNEIAKLEMVI 414 K + +S +A + + +L S N ++TD + K E K E + Sbjct: 1364 KNFKEERIAELESLLGSAPEEDVDLKEERVMELESHLANVLEETDS-LRKAEAWKDERIS 1422 Query: 415 Q---SLNKDLVDKEYVISEKDTXXXXXXXXXXGK-DTLIAQLQLEHQQHMEGPSLIHVGT 470 + L + + DKE +K T + + L + ++ +Q E S + Sbjct: 1423 ELESRLGEVVNDKESGAEDKATELEAQLASVLQEVEALREEKNVKEEQISELESRLANVQ 1482 Query: 471 NTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVK 530 ++ E +V +Q Q L+D +++++ + E+L EE+I QL + + + ++ Sbjct: 1483 QDKEGEEEGRVVKQDSQ-LSDALQELDA--MKEELTLREEKIAQLESWLTTGMQEIEVLR 1539 Query: 531 SNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDS 590 ++ QM + + VS E ++ E HL+ V E++ + L+ D Sbjct: 1540 QEKDVREAQMTELESRLAIVSKEISEEGKVAELESHLTNVVGEMDSLREEKNLNK---DK 1596 Query: 591 GRMIESDVYKKMIEMENLAETR-LK--AISLLESQKFDLVQELHILQQKYDEVEDKLADI 647 +ESD+ + E+E L E + LK IS LE++ QE + K E+E LA + Sbjct: 1597 VAELESDLASVVQELEALKEEKNLKDEEISDLEARLTSESQEKSAEEDKVVELESDLASV 1656 Query: 648 SQ-LQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDI 706 Q L++ + +K + + L++ +E + E + + L G +++LE KE+ Sbjct: 1657 VQELEALKEEKNLKDEQISDLEARLNSDSQEKSAEEEKVVELESHLTGVLQELEALKEEK 1716 Query: 707 MNKLQNYIQENMDLTD---KLEKMSAEKI--SELLAKINHEEQSKIQTQ-FGIDAKIQER 760 K+ +++ L D +LE ++ +K E +A++ + Q Q + K+ E Sbjct: 1717 NQKVGKFLEMQSHLNDARQELEFLNEDKNLREEQMAELKSRFANVSQEQDIFREEKVAEA 1776 Query: 761 DLYIENIESELSKYKS-------RICRLEESIA-VMEDRRYSLERKADQLGS----YLQE 808 + + N+ E+ K + LE +A V +++ E K +L S LQE Sbjct: 1777 ESKLANVLQEIEALKEGKNLREQHMAELEAMLAHVSQEQDTVREEKVLELESRLSCVLQE 1836 Query: 809 KQKAYSEYTIQE---DELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNL 865 E T++E EL R + +++ ++ +L I+ E L+ N ++ + Q Sbjct: 1837 MDTLKVEETLKEAKATELETRHSEVLNDMERLQDELTRIKDEKARLEAANYEIMSQMQKD 1896 Query: 866 QISL--------SDMQQHYN--ALVEKANRT------DLAE--SESTKYQTQLRDLESNL 907 +++ ++++Q ++ A +EK + ++ E ++S+ +L +L+ L Sbjct: 1897 VVTMETQTEEDVAEVEQSHDLHAAIEKLRKVLTSKDQEICEVKAQSSHEMGRLEELQQCL 1956 Query: 908 K--------RITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQ 959 + RIT E + L +K + +E ++ ++ +I + +L E+ E + + Sbjct: 1957 EEESREREERITAELRNLEAEKTR-LEAALVKAELELGDSISETCLLKEEMEMMESRLAE 2015 Query: 960 -LEAQLQEYKNNIENLNMNVEELNKM------NLELIDKHVQKQQTQSPDYTEQYINEIN 1012 E+ L + + +E L + ++ + +E + + ++ + ++ Q +E Sbjct: 2016 GRESALGQQQQEMEELMVELDSARNLLSQKEDEIEKLQEFMKLENEEAIKQEAQSRHETK 2075 Query: 1013 KLNALLKQKDEEIIALNQKINN-AQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQL 1071 +L+ LL+Q + E + ++I + S+ + + + + + + + +E + ++ Sbjct: 2076 RLHNLLQQLEGESKLVKEQIRQECETSWQVVCEELRTAMQESEREKQRLEAALWNAEEKQ 2135 Query: 1072 LDSKQHNEE-LQILVREQDDQIKELKETKLTFEMNIPKTEGM--IISSTIEPMSDDANNV 1128 + S Q +E LQ + E ++E + K E+ + K E + ++ D+ V Sbjct: 2136 VQSHQFSEHRLQGVCEELRTAMEESEREKERLEVALRKAEEKQESLEKEVKKRKDEVKRV 2195 Query: 1129 DXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTE---LQECYTKIIQLETLNTEL 1185 VQ+ EE + ++ E KL+ E L E K+ Q E L EL Sbjct: 2196 RIESFK--------NVQDWEE--RANTICGEIQEKLDEEQAKLSETKEKLSQFEVLCEEL 2245 Query: 1186 TGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQ 1245 E+I+++K + + + L A+++ ++ V ++ E A+ Sbjct: 2246 KEELKAKDEEIDRVKEDKRDIFNKKEMLEKQYAKMKKQVNQTVQSSIRDVGEA----EAR 2301 Query: 1246 READFQKTEHELRVQLSAFESKYEQL------LDSVQSSTQEETNKIVTMEQVT--SLQN 1297 A ++ E EL + + + E++ + +++ Q + + + T SL++ Sbjct: 2302 ANAVCEELEEELEAEKTKVKDAQEKVECQAKHICELEAKLQSQLTQSKGGDPTTRRSLES 2361 Query: 1298 KLQDKEEHLRNLQEKYADVINQIEILRSEIEDEK 1331 +L K+ + L+ ++ I ++E +++ EK Sbjct: 2362 ELSAKKREMTVLEMEHTREILKLEERIRDLDSEK 2395 Score = 94.3 bits (224), Expect = 2e-17 Identities = 195/1009 (19%), Positives = 428/1009 (42%), Gaps = 99/1009 (9%) Query: 619 LESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQI-DALSASKKE 677 LES + ++ +L+ K +V ++ A +++Q+ + ++ L+ I ++ + E Sbjct: 562 LESAQEEIKTLKEMLEGKESDVLERQAREAEMQAALDSANLEKEELKSHISESQNKELME 621 Query: 678 LALVIENLKLDKEQLYGTIKDLENDKE----DIMNK-------LQNYIQEN-----MDLT 721 L +++ L+K +L + +++ ++ D +N L+N++ E+ M+L Sbjct: 622 LQAALDSANLEKAELKSRMAEIQEGQQTGMQDALNAANLEIEVLKNHVSESQNKELMELQ 681 Query: 722 DKLE--KMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRIC 779 L+ ++ ++ +A+I E+Q++IQ G A ++ +L +++ +E + ++ Sbjct: 682 AALDTANLANAELMSRMAEIEKEQQTEIQAALG-SANLENAEL--KSLMAE--QQNKQLM 736 Query: 780 RLEESIAVMEDRRYSLERKADQL-GSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVE 838 L++++ L+ Q+ L E Q ++ +EL + LA V Sbjct: 737 ELQDALNTANLEIEVLKNHMTQVQNEQLMETQAVLDAANLENEELKSHLA------DVQN 790 Query: 839 KQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQT 898 KQL+E LQ + EN +++ L M+ +AL E + + E Q Sbjct: 791 KQLME-------LQAALDLANAENADIKSRLGSMET--DALTEAMTTLEKSHKELAVLQA 841 Query: 899 QLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIES-AIRDKKVLNEKY---EKNI 954 L + H + Q + E+E E ++ E RD LNE EK Sbjct: 842 ALDSANQEREAFGEVHISENSQLRTELESASRELHSLKEQYEERDTTRLNEALATLEKQA 901 Query: 955 EYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKL 1014 +T+L+A L+ + E L EE+ +L I ++ Q QS +++ ++ Sbjct: 902 ADLTELQAALEISRGEKETLERRSEEMPSSDLNDIKATLESSQ-QS--------DQVREM 952 Query: 1015 NALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDS 1074 +L+ EE AL ++ Q ++ V E + ++ M E++ +S L D+ Sbjct: 953 QVVLETLTEENAALKDRLEELQTKDVNQVQVEEPE------EILVMRAELE-MSSALCDA 1005 Query: 1075 KQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTI--EPMSDDANNVDXXX 1132 Q EE L + D+ I + + T ++ K +G ++ S E ++++ N + Sbjct: 1006 LQ--EEKDQLQTKLDETIPDAAQATQTPHPDVDKLKGELMESLTLCEALNEEKNQLHSKL 1063 Query: 1133 XXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVN 1192 ++ E + I+ ++E+ A+L L + + +L+ T + Sbjct: 1064 EETRKEIE-MRTDESSDIIK----MKEEIAELRFVLLQKAEEYAELQQF-TRWEDKSLKE 1117 Query: 1193 QEQINQLK-SKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQ 1251 QE Q + ++L+++ + D L ++ + I++ + Q E +L Q A++E + Sbjct: 1118 QESEYQCEINRLQEIMKQKDKDLR---DIETKITAQLTQSENEKTDLDFQLDAEKERNRS 1174 Query: 1252 KTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVT--MEQVTSLQNKLQDKEEHLRNL 1309 T ELR QL + ++ + + ++ EE ++ T E V L+ +L + + +L Sbjct: 1175 MTS-ELRQQLQEAYDRLKEK-EGAEGASAEEGMELETEKRENVVELEVRLAEVLREMESL 1232 Query: 1310 QEKYA---DVINQIEI-LRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQ 1365 +EK + +++ ++E L +++++ ++ + K ++E+ Sbjct: 1233 REKESQKEEMVTELETKLAGALQEKENVEEKKVHELESRLASILMEIEALKKE-KTVREE 1291 Query: 1366 SILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTI 1425 + ++ + A + ++ + E++ L L+ +D E +K E + Sbjct: 1292 KVCDLEAKLANAVQEIDTLREEETLKEQKMVELESR---LNMVLQEQDGEKEEKLLELSS 1348 Query: 1426 TLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERV 1485 L E E +R++ E+RI +L ++L E+ + E E E Sbjct: 1349 KLANLLQETEELREEKNFKEERIAELE-------SLLGSAPEEDVDLKEERVMELESHLA 1401 Query: 1486 KLIEELNVKITESVSLNKQVAELNKALEEEV----AKTNEMQTALENQEIEIVTLNDEIT 1541 ++EE + +++++EL L E V + + T LE Q ++ + + Sbjct: 1402 NVLEETDSLRKAEAWKDERISELESRLGEVVNDKESGAEDKATELEAQLASVLQEVEALR 1461 Query: 1542 NLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELD 1590 +N+ S+++ ++ K+G +E + +L DA+ ELD Sbjct: 1462 EEKNVKEEQISELESRLANVQQDKEGEEEGRVVKQDSQLSDAL--QELD 1508 Score = 43.2 bits (97), Expect = 0.061 Identities = 98/570 (17%), Positives = 254/570 (44%), Gaps = 50/570 (8%) Query: 218 MTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQE 277 M++MQ++ + ME + +++ + ++E +++E+ K+L + EI ++ + E Sbjct: 1890 MSQMQKDVVTMETQTEED----VAEVEQSHDLHAAIEKLRKVLTSKDQEICEVKAQSSHE 1945 Query: 278 LEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIE-EKGSLEIANMTELTKKIELLEHLN- 335 + + +++ E E +E EK LE A + ++EL + ++ Sbjct: 1946 MGRLEELQQCLEEE----SREREERITAELRNLEAEKTRLEAALVKA---ELELGDSISE 1998 Query: 336 -CQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETL 394 C +++ + +E++LA G ES + ++ S RN S+ + +L E + Sbjct: 1999 TCLLKEEMEMMESRLAE-GRESALGQQQQEMEELMVELDSARNLLSQKEDEIEKLQ-EFM 2056 Query: 395 NQDTDKKINKNEIAKLEMV-IQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQ 453 + ++ I + ++ E + +L + L + ++ E+ ++ A + Sbjct: 2057 KLENEEAIKQEAQSRHETKRLHNLLQQLEGESKLVKEQIRQECETSWQVVCEELRTAMQE 2116 Query: 454 LEHQQHMEGPSLIH-----VGTNTEDVNEIAKVQEQLKQELND-----EIKDVNVKDLIE 503 E ++ +L + V ++ + + V E+L+ + + E +V ++ E Sbjct: 2117 SEREKQRLEAALWNAEEKQVQSHQFSEHRLQGVCEELRTAMEESEREKERLEVALRKAEE 2176 Query: 504 KLKSAEEQITQLNDEIDAAN----KNMIKVKSNHKLKLKQMQKTIDNF-SKVSDSNKEIV 558 K +S E+++ + DE+ KN+ + ++Q+ +D +K+S++ +++ Sbjct: 2177 KQESLEKEVKKRKDEVKRVRIESFKNVQDWEERANTICGEIQEKLDEEQAKLSETKEKLS 2236 Query: 559 R-------LTEELHHLSQKVAELEEEKGNL--QLHLVDYDSGRMIESDVYKKMIEMENLA 609 + L EEL +++ ++E+K ++ + +++ +M + + ++ Sbjct: 2237 QFEVLCEELKEELKAKDEEIDRVKEDKRDIFNKKEMLEKQYAKMKKQVNQTVQSSIRDVG 2296 Query: 610 ETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADI----SQLQSDQVCSEIKSVHLE 665 E +A ++ E + +L E ++ ++VE + I ++LQS S+ Sbjct: 2297 EAEARANAVCEELEEELEAEKTKVKDAQEKVECQAKHICELEAKLQSQLTQSKGGDPTTR 2356 Query: 666 EQIDA-LSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNY----IQENMDL 720 +++ LSA K+E+ ++ + +L I+DL+++K+ + K + Y +E+ Sbjct: 2357 RSLESELSAKKREMTVLEMEHTREILKLEERIRDLDSEKKFLDEKNREYRNELRREHQRA 2416 Query: 721 TDKLEKMSAEKISELLAKINHEEQSKIQTQ 750 D + +S + + +L + + SK++ + Sbjct: 2417 ADSSDTVSQKHLFVVLYVFHRDRNSKLKQE 2446 Score = 37.5 bits (83), Expect = 3.0 Identities = 52/235 (22%), Positives = 102/235 (43%), Gaps = 15/235 (6%) Query: 1363 QEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAK-VLELTHQLELKDSEIYQ-KT 1420 +E +L A+++ + +++++ K ++EL L+ + E + K+ Sbjct: 579 KESDVLERQAREAEMQAALDSANLEKEELKSHISESQNKELMELQAALDSANLEKAELKS 638 Query: 1421 HEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHE-NANHYETMQKE 1479 I Q+ + + +E E ++ + EL L+ + N + E M + Sbjct: 639 RMAEIQEGQQTGMQDALNAANLEIEVLKNHVSESQNKELMELQAALDTANLANAELMSRM 698 Query: 1480 SEIERVKLIEELNVKITESV-SLNKQVAELNKALEEEVAKT-NEMQTALENQEIEIVTLN 1537 +EIE+ E +I ++ S N + AEL + E+ K E+Q AL +EI L Sbjct: 699 AEIEK-----EQQTEIQAALGSANLENAELKSLMAEQQNKQLMELQDALNTANLEIEVLK 753 Query: 1538 DEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDLA 1592 + +T +QN + Q + A+ + L + NK+L++ +A LDLA Sbjct: 754 NHMTQVQN---EQLMETQAVLDAANLENEELKSHLADVQNKQLMEL--QAALDLA 803 >UniRef50_A2DUI3 Cluster: Viral A-type inclusion protein, putative; n=1; Trichomonas vaginalis G3|Rep: Viral A-type inclusion protein, putative - Trichomonas vaginalis G3 Length = 1262 Score = 132 bits (319), Expect = 8e-29 Identities = 210/1104 (19%), Positives = 472/1104 (42%), Gaps = 108/1104 (9%) Query: 484 QLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKT 543 Q + ++ K++ KD K +A + + + + + SN K K +K Sbjct: 109 QSSKSSSNVTKNIKFKDFSAKQTTASKLASDMKQSYSEFVSSSQNLFSNLK---KLTKKV 165 Query: 544 IDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMI 603 + S + S+K + + QK+ E E + L+ L+ +S + + Y+ Sbjct: 166 VAKQSSIIQSDKRFISEAKS----QQKIDEAEINR--LKQQLISTES----QLNHYRTQ- 214 Query: 604 EMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVH 663 L+ R K + +++E L+++ ++ KL + S + +D+ +E++ Sbjct: 215 ----LSNIRAKPADKTDYSYNSIIEENERLKKENRDLSQKLRNSSSIVTDKNETELEKEA 270 Query: 664 LEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDK 723 ++Q++ E+ L ++L +K+ ++ +N LQN I E +L +K Sbjct: 271 KDKQLELALEHIDEIDNERRRLININKKLLNKVKEYSQSNDESLN-LQNIISEKSELNEK 329 Query: 724 LE------KMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSR 777 ++ + EK++ + + HE + + K ++ + +++ EL+ S Sbjct: 330 MDAEMKILRNDKEKLNIEIETLKHENEELKKNNKKQIVKYKQLETDYRDLKIELNPIISE 389 Query: 778 ICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVV 837 +++E + +R+ S+E +D + + E++ E + E + L + + ++ Sbjct: 390 NEKMKEEVD--NERQKSMESMSDT--AKVTEREAHLMEEISKHKEKIQNLEISLSKEKKF 445 Query: 838 EKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQ 897 K L + E E +++++ + L+EEN+N++ L+ + +L +K + + +S + Sbjct: 446 SKSLSKSEEELTQVKRQMEDLMEENENIKEILA---KSVESLKKKKSEINDLKSLVENQK 502 Query: 898 TQLRDLESNLKRITHEHQTLIVQKKKEIEDL--EIEFNTQIESAIRD---KKVLNEKYEK 952 T++ D+E + + + +E I Q+KKEIE L EIE N + RD K + + EK Sbjct: 503 TEISDVEKSKEELYNE----IEQQKKEIEQLKKEIERNDMNFNNYRDMSNKTLRKTEEEK 558 Query: 953 N------IEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELID--KHVQKQQ----TQS 1000 N ++Y + + YK L +E++ + ++ D K + K Q ++S Sbjct: 559 NEIERQFVKYKLDTNTESETYKTLQTTLTDRNDEISNLRKKVSDFQKEIIKMQEEMHSKS 618 Query: 1001 PDYTE---QYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKL 1057 D+ + ++ N+I L L + ++I+ ++ + + YE+ + + ++ Sbjct: 619 KDFDKNKAEFTNKIKNLEKLNEDLRSQVISSQNTRKKSEDMMEASMKQYENDILNLSQQI 678 Query: 1058 ENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISST 1117 E+ Q + KQ ++ +++ + E +D+I + KE KL ++ + + I S Sbjct: 679 ESNNSNHQEIIKQC--KEESGNKIKEIEAEYEDKINKQKE-KLENKIKDIEFQYSEIKSK 735 Query: 1118 IEPMSDDANNVDXXXXXXXXXXXXL--KVQEEEEFIQERSVLQEQSAKLNTELQECYTKI 1175 E +++ L ++ EF + ++E++ KLN Sbjct: 736 YEEVNNQIQEASQMKETFDNCCISLFGSIKTSNEFSSLINQMKEENLKLN---------- 785 Query: 1176 IQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEI 1235 +L N LTG ++ ++ + L +EN NL + + + S S + + Sbjct: 786 -ELSKTNEILTG-------KLGKIYMANKILKSENANLKNNLV-ISSQSSRKISDEFKNL 836 Query: 1236 AELWKQ--HLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQV- 1292 ++ + + + ++ + KT +E +L+ + + S + TN +E+ Sbjct: 837 SKKYNELNNSSENLTNDNKTLNEKNQKLNELNNNLSSEFLKLSSQNEVLTNNQKILEEKH 896 Query: 1293 TSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDL 1352 LQN + EE+ + L ++ ++ E L E K + D+ Sbjct: 897 NKLQNDHKQLEENFQKLNNEHQELTTNYEKLTENHEKLKKEYETATSELSISMN----DV 952 Query: 1353 RTENQSYKQMQEQSILNINEE-------NAQLKKSSXXXXXXXXXXXXRVNDAEAKVLEL 1405 + YKQ++++ I NIN + N +LK ++ + + E+ Sbjct: 953 NELTEHYKQLKDE-IFNINNQYNEIISDNERLKTELELTKDELNESNNNLSKIKLENEEM 1011 Query: 1406 THQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLK 1465 + L + +S+ + +E L + N E EN+ L +K I E + L L K Sbjct: 1012 SKSLNISESDKKKLENE----LEENNREIENISLSL---DKEISK-NDELQKCLTKLSSK 1063 Query: 1466 MHENANHYETM-QKESEIERV-KLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEM- 1522 + ++++ + + ++ E++ K I + N K+ ++ N Q+ ++NK E + E+ Sbjct: 1064 ITDSSSRIDDLSERNKEMKEYNKQILQENKKLKRKLNSNSQIPDINKLQSENKTLSQELF 1123 Query: 1523 QTALENQEI--EIVTLNDEITNLQ 1544 + ENQE+ + T+ ++ L+ Sbjct: 1124 KLKDENQELLERVATMTLSLSQLE 1147 Score = 116 bits (278), Expect = 7e-24 Identities = 186/986 (18%), Positives = 422/986 (42%), Gaps = 72/986 (7%) Query: 148 SNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXX 207 S+ + +K+ + K K +E + + E NE+ ++I K Sbjct: 255 SSIVTDKNETELEKEAKDKQLELALEHIDEIDNERRRLININKKLLNKVKEYSQSNDESL 314 Query: 208 XXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEI 267 ++ + +++ E A +++K++L +IE+ L++ NK ++ Sbjct: 315 NL--QNIISEKSELNEKMDAEMKILRNDKEKLNIEIETLKHENEELKKNNKKQIVKYKQL 372 Query: 268 SLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKK 327 ++ L EL ++S+E S + ++ E+ + + +++ +K Sbjct: 373 ETDYRDLKIELNPIISENEKMKEEVDNERQKSME-SMSDTAKVTEREAHLMEEISKHKEK 431 Query: 328 IELLEHLNCQIRQTNKEL---ENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKS 384 I+ LE + ++ +K L E +L + + + + ++ ++++ + K KS Sbjct: 432 IQNLEISLSKEKKFSKSLSKSEEELTQVKRQMEDLMEENENIKEILAKSV--ESLKKKKS 489 Query: 385 PWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXG 444 + L S NQ T+ + +L I+ K++ + I D Sbjct: 490 EINDLKSLVENQKTEISDVEKSKEELYNEIEQQKKEIEQLKKEIERNDMNFNNYRDMS-- 547 Query: 445 KDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEK 504 + + + + E + + TNTE +E K + + NDEI ++ +K Sbjct: 548 -NKTLRKTEEEKNEIERQFVKYKLDTNTE--SETYKTLQTTLTDRNDEISNLR-----KK 599 Query: 505 LKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEEL 564 + +++I ++ +E+ + +K+ K K+ K+K ++K ++ S++ + +E++ Sbjct: 600 VSDFQKEIIKMQEEMHSKSKDFDKNKAEFTNKIKNLEKLNEDLRSQVISSQNTRKKSEDM 659 Query: 565 HHLSQKVAELEEEKGNLQLHLVDYDSG-----RMIESDVYKKMIEMENLAETRL-KAISL 618 S K + E + NL + +S + + + K+ E+E E ++ K Sbjct: 660 MEASMK--QYENDILNLSQQIESNNSNHQEIIKQCKEESGNKIKEIEAEYEDKINKQKEK 717 Query: 619 LESQKFDLVQELHILQQKYDEVEDKLADISQLQS--DQVC-SEIKSVHLEEQIDALSASK 675 LE++ D+ + ++ KY+EV +++ + SQ++ D C S S+ + +L Sbjct: 718 LENKIKDIEFQYSEIKSKYEEVNNQIQEASQMKETFDNCCISLFGSIKTSNEFSSLINQM 777 Query: 676 KELALVIENLKLDKEQLYGTI-------KDLENDKEDIMNKLQNYIQENMDLTDKLEKMS 728 KE L + L E L G + K L+++ ++ N L Q + ++D+ + +S Sbjct: 778 KEENLKLNELSKTNEILTGKLGKIYMANKILKSENANLKNNLVISSQSSRKISDEFKNLS 837 Query: 729 AEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVM 788 +K +EL N+ ++ ++ K Q+ + N+ SE K S+ L + ++ Sbjct: 838 -KKYNEL----NNSSENLTNDNKTLNEKNQKLNELNNNLSSEFLKLSSQNEVLTNNQKIL 892 Query: 789 EDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHEN 848 E++ L+ QL Q+ + E T ++L +H+++ ++ + Sbjct: 893 EEKHNKLQNDHKQLEENFQKLNNEHQELTTNYEKLTE------NHEKLKKEYETATSELS 946 Query: 849 KELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLK 908 + N+ L E + L+ + ++ YN ++ R E E TK +L + +NL Sbjct: 947 ISMNDVNE-LTEHYKQLKDEIFNINNQYNEIISDNERLK-TELELTK--DELNESNNNLS 1002 Query: 909 RITHEHQ------TLIVQKKKEIEDLEIEFNTQIE--SAIRDKKVLNEKYEKNIEYVTQL 960 +I E++ + KK++E+ E N +IE S DK++ K ++ + +T+L Sbjct: 1003 KIKLENEEMSKSLNISESDKKKLENELEENNREIENISLSLDKEI--SKNDELQKCLTKL 1060 Query: 961 EAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQ 1020 +++ + + I++L+ +E+ + N +++ ++ + ++ + + I +INKL + K Sbjct: 1061 SSKITDSSSRIDDLSERNKEMKEYNKQILQENKKLKRKLN---SNSQIPDINKLQSENKT 1117 Query: 1021 KDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEE 1080 +E+ K+ + + V+ L+Q + E EEE +S Q H EE Sbjct: 1118 LSQELF----KLKDENQELLERVATMTLSLSQL--EFEE-EEETMLLSPQFDQLNNHTEE 1170 Query: 1081 -LQILVREQDDQIKELKETKLTFEMN 1105 ++ ++ K + LT +N Sbjct: 1171 KIKSVISSPRSSKKRNRPVFLTQSLN 1196 Score = 105 bits (251), Expect = 1e-20 Identities = 169/897 (18%), Positives = 390/897 (43%), Gaps = 69/897 (7%) Query: 705 DIMNKLQNYIQENMDL-----TDKLEKM--SAEKISELLAKINHEEQSKIQT---QFGID 754 ++ N+L YI++ M T+ KM S++ S + I ++ S QT + D Sbjct: 80 NVPNELNQYIRDLMKTKKSFPTNSTNKMIQSSKSSSNVTKNIKFKDFSAKQTTASKLASD 139 Query: 755 AKIQERDLYI--ENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKA 812 K + +N+ S L K ++ + SI + D+R+ E K+ Q + + Sbjct: 140 MKQSYSEFVSSSQNLFSNLKKLTKKVVAKQSSI-IQSDKRFISEAKSQQ--KIDEAEINR 196 Query: 813 YSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDM 872 + I + +N + + R K + ++ + ++N+ L +EN++L L Sbjct: 197 LKQQLISTESQLNHYRTQLSNIRA--KPADKTDYSYNSIIEENERLKKENRDLSQKL--- 251 Query: 873 QQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEF 932 ++ +++V N T+L E E+ Q +L LE ++ I +E + LI KK + ++ E+ Sbjct: 252 -RNSSSIVTDKNETEL-EKEAKDKQLELA-LE-HIDEIDNERRRLININKKLLNKVK-EY 306 Query: 933 NTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKH 992 + + ++ + +++EK E N +++A+++ +N+ E LN+ +E L N EL K+ Sbjct: 307 SQSNDESLNLQNIISEKSELN----EKMDAEMKILRNDKEKLNIEIETLKHENEEL-KKN 361 Query: 993 VQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSD---YESK 1049 +KQ + Y + +LN ++ + ++ + ++++N + M +SD + Sbjct: 362 NKKQIVKYKQLETDYRDLKIELNPIISENEK----MKEEVDNERQKSMESMSDTAKVTER 417 Query: 1050 LAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKT 1109 A ++ +E++Q + L K+ ++ L E+ Q+K E + NI + Sbjct: 418 EAHLMEEISKHKEKIQNLEISLSKEKKFSKSLS-KSEEELTQVKRQMEDLMEENENIKEI 476 Query: 1110 EGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQ 1169 + S ++ + N++ ++ + +EE E +++ +L E++ Sbjct: 477 LAKSVES-LKKKKSEINDLKSLVENQKTEISDVE-KSKEELYNEIEQQKKEIEQLKKEIE 534 Query: 1170 ECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVD 1229 ++ + +E+ N+++ + + + + T +E ++ + + Sbjct: 535 RNDMNFNNYRDMSNKTLRK---TEEEKNEIERQFVKYKLDTN----TESETYKTLQTTLT 587 Query: 1230 QRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTM 1289 R EI+ L K+ ++ + + K + E+ + F+ + + +++ E+ N+ + Sbjct: 588 DRNDEISNLRKK-VSDFQKEIIKMQEEMHSKSKDFDKNKAEFTNKIKNL--EKLNEDLR- 643 Query: 1290 EQVTSLQNKLQDKEEHLRNLQEKYA-DVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXX 1348 QV S QN + E+ + ++Y D++N + + S + + Sbjct: 644 SQVISSQNTRKKSEDMMEASMKQYENDILNLSQQIESNNSNHQEIIKQCKEESGNKIKEI 703 Query: 1349 XXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQ 1408 + + K+ E I +I + +++K ++ +A +++ E Sbjct: 704 EAEYEDKINKQKEKLENKIKDIEFQYSEIKSK-------YEEVNNQIQEA-SQMKETFDN 755 Query: 1409 LELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHE 1468 + + ++E++ + Q +E N++ L E K E LT + ++ E Sbjct: 756 CCISLFGSIKTSNEFSSLINQMKEE--NLK--LNELSKTNEILTGKLGKIYMANKILKSE 811 Query: 1469 NANHYETMQKESEIERVKLIEE---LNVKITESVSLNKQVAELNKALEEEVAKTNEMQTA 1525 NAN + S+ R K+ +E L+ K E + ++ + NK L E+ K NE+ Sbjct: 812 NANLKNNLVISSQSSR-KISDEFKNLSKKYNELNNSSENLTNDNKTLNEKNQKLNELNNN 870 Query: 1526 LENQEIEIVTLNDEITNLQNMVRASSSKIQK-HVSFASDTKQGRDEQLDNTMNKELL 1581 L ++ +++ + N+ +TN Q ++ +K+Q H + ++ +E + T N E L Sbjct: 871 LSSEFLKLSSQNEVLTNNQKILEEKHNKLQNDHKQLEENFQKLNNEHQELTTNYEKL 927 Score = 104 bits (250), Expect = 2e-20 Identities = 181/977 (18%), Positives = 414/977 (42%), Gaps = 65/977 (6%) Query: 355 ESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQ-DTDKK----INKNEIAK 409 E++ +S + S +++ K+ + K +L+ E +++ D +++ INK + K Sbjct: 243 ENRDLSQKLRNSSSIVTDKNETELEKEAKDKQLELALEHIDEIDNERRRLININKKLLNK 302 Query: 410 LEMVIQSLNKDLVDKEYVISEKD--TXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIH 467 ++ QS N + ++ + +ISEK D +++E +H + Sbjct: 303 VKEYSQS-NDESLNLQNIISEKSELNEKMDAEMKILRNDKEKLNIEIETLKHENEELKKN 361 Query: 468 VGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLND--EIDAANKN 525 ++ LK ELN I + N K E ++ + ++D ++ + Sbjct: 362 NKKQIVKYKQLETDYRDLKIELNPIISE-NEKMKEEVDNERQKSMESMSDTAKVTEREAH 420 Query: 526 MIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHL 585 +++ S HK K++ ++ ++ K S K + + EEL + +++ +L EE N++ L Sbjct: 421 LMEEISKHKEKIQNLEISLSKEKKFS---KSLSKSEEELTQVKRQMEDLMEENENIKEIL 477 Query: 586 VDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLA 645 + +ES + KK E+ +L SL+E+QK ++ ++ Y+E+E + Sbjct: 478 A-----KSVES-LKKKKSEINDLK-------SLVENQKTEISDVEKSKEELYNEIEQQKK 524 Query: 646 DISQLQSDQVCSEIKSVHLEEQ----IDALSASKKELALVIENLKLDKEQLYGTIKDLEN 701 +I QL+ + +++ + + + K E+ KLD T K L+ Sbjct: 525 EIEQLKKEIERNDMNFNNYRDMSNKTLRKTEEEKNEIERQFVKYKLDTNTESETYKTLQT 584 Query: 702 DKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERD 761 D +++ N ++ D ++ KM E S+ +K + +++ + K+ E D Sbjct: 585 TLTDRNDEISNLRKKVSDFQKEIIKMQEEMHSK--SKDFDKNKAEFTNKIKNLEKLNE-D 641 Query: 762 LYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQE--KQ-KAYSEYTI 818 L + I S+ ++ KS +E S+ E+ +L ++ + S QE KQ K S I Sbjct: 642 LRSQVISSQNTRKKSEDM-MEASMKQYENDILNLSQQIESNNSNHQEIIKQCKEESGNKI 700 Query: 819 QEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNA 878 +E E + +++ E ++ +IE + E++ K + E N +Q S M++ ++ Sbjct: 701 KEIEAEYEDKINKQKEKL-ENKIKDIEFQYSEIKSKYE---EVNNQIQ-EASQMKETFDN 755 Query: 879 LVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTL------IVQKKKEIEDLEIEF 932 + +E + Q+++ L ++ ++ L I K ++ Sbjct: 756 CCISLFGSIKTSNEFSSLINQMKEENLKLNELSKTNEILTGKLGKIYMANKILKSENANL 815 Query: 933 NTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKH 992 + + + + ++++++ + +L + N+ + LN ++LN++N L + Sbjct: 816 KNNLVISSQSSRKISDEFKNLSKKYNELNNSSENLTNDNKTLNEKNQKLNELNNNLSSEF 875 Query: 993 VQ-KQQTQSPDYTEQYINEI-NKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKL 1050 ++ Q + ++ + E NKL KQ +E LN + +Y + ++E Sbjct: 876 LKLSSQNEVLTNNQKILEEKHNKLQNDHKQLEENFQKLNNEHQELTTNYEKLTENHEKLK 935 Query: 1051 AQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTE 1110 ++ T + M V++ KQ +E+ + + ++ I + +L E+ + K E Sbjct: 936 KEYETATSELSISMNDVNELTEHYKQLKDEIFNINNQYNEIISD--NERLKTELELTKDE 993 Query: 1111 GMIISSTIEPMSDDANNVDXXXXXXXXXXXXLK--VQEEEEFIQERSVLQEQSAKLNTEL 1168 ++ + + + + L+ ++E I+ S+ ++ N EL Sbjct: 994 LNESNNNLSKIKLENEEMSKSLNISESDKKKLENELEENNREIENISLSLDKEISKNDEL 1053 Query: 1169 QECYTKI-IQLETLNTELTGHDVVNQE------QINQLKSKLEQLNTENDNLLSTVAELR 1221 Q+C TK+ ++ ++ + N+E QI Q KL++ N + + +L+ Sbjct: 1054 QKCLTKLSSKITDSSSRIDDLSERNKEMKEYNKQILQENKKLKRKLNSNSQ-IPDINKLQ 1112 Query: 1222 SSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQE 1281 S + + Q F++ + Q L +R A + +L + D + + T+E Sbjct: 1113 SE-NKTLSQELFKLKD-ENQELLERVATMTLSLSQLEFEEEEETMLLSPQFDQLNNHTEE 1170 Query: 1282 ETNKIVTMEQVTSLQNK 1298 + +++ + + +N+ Sbjct: 1171 KIKSVISSPRSSKKRNR 1187 Score = 84.2 bits (199), Expect = 3e-14 Identities = 187/949 (19%), Positives = 389/949 (40%), Gaps = 73/949 (7%) Query: 94 LANTLKQKEILMEKIK-QYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIK 152 L N ++ I +E +K + +EL K + IV+ +L + +S K Sbjct: 337 LRNDKEKLNIEIETLKHENEELKKNNKKQIVKYKQLETDYRDLKI--ELNPI--ISENEK 392 Query: 153 EKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXE 212 K+ + Q M+ M T + + + ++I +K+K Sbjct: 393 MKEEVDNERQKSMESMSDTAKVTEREAHLMEEI--SKHKEKIQNLEISLSKEKKFSKSLS 450 Query: 213 DTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEIS-LEH 271 +++++T+++ + E ++ K+ L K +ES + S + + L+E + EIS +E Sbjct: 451 KSEEELTQVKRQMEDLMEENENIKEILAKSVESLKKKKSEINDLKSLVENQKTEISDVEK 510 Query: 272 SK--LAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIE 329 SK L E+EQ K+ IE + ++ +++N T L K E Sbjct: 511 SKEELYNEIEQQKKEIEQL--------KKEIE-----RNDMNFNNYRDMSNKT-LRKTEE 556 Query: 330 LLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQL 389 + Q + + + T T ++ + + S L RK + ++ ++ Sbjct: 557 EKNEIERQFVKYKLDTNTESETYKTLQTTLTDRNDEISNL--RKKVSDFQKEIIKMQEEM 614 Query: 390 SSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISE-KDTXXXXXXXXXXGKDTL 448 S++ + D +K N+I LE + + L ++ + + +D L Sbjct: 615 HSKSKDFDKNKAEFTNKIKNLEKLNEDLRSQVISSQNTRKKSEDMMEASMKQYENDILNL 674 Query: 449 IAQLQLEHQQHME---------GPSLIHVGTNTEDVNEIAKVQEQLKQELND-EIKDVNV 498 Q++ + H E G + + ED +I K +E+L+ ++ D E + + Sbjct: 675 SQQIESNNSNHQEIIKQCKEESGNKIKEIEAEYED--KINKQKEKLENKIKDIEFQYSEI 732 Query: 499 KDLIEKLKSAEEQITQLNDEIDAANKNM---IKVKSNHKLKLKQMQKTIDNFSKVSDSNK 555 K E++ + ++ +Q+ + D ++ IK + + QM++ +++S +N Sbjct: 733 KSKYEEVNNQIQEASQMKETFDNCCISLFGSIKTSNEFSSLINQMKEENLKLNELSKTN- 791 Query: 556 EIVRLTEELHHLSQKVAELEEEKGNLQLHLV-DYDSGRMIESDVYKKMIEMENLAETRLK 614 EI LT +L + L+ E NL+ +LV S R I SD +K + + N E Sbjct: 792 EI--LTGKLGKIYMANKILKSENANLKNNLVISSQSSRKI-SDEFKNLSKKYN--ELNNS 846 Query: 615 AISLLESQKFDLVQELHILQQKYDEVEDKLA-DISQLQSDQVCSEIKSVHLEEQIDALSA 673 + +L K L+ QK +E+ + L+ + +L S LEE+ + L Sbjct: 847 SENLTNDNK-----TLNEKNQKLNELNNNLSSEFLKLSSQNEVLTNNQKILEEKHNKLQN 901 Query: 674 SKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQE-NMDLTDKLEKMSAEK- 731 K+L + L + ++L + L + E + + + E ++ + D E K Sbjct: 902 DHKQLEENFQKLNNEHQELTTNYEKLTENHEKLKKEYETATSELSISMNDVNELTEHYKQ 961 Query: 732 ISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDR 791 + + + IN++ I + +++ + + LSK K + +S+ + E Sbjct: 962 LKDEIFNINNQYNEIISDNERLKTELELTKDELNESNNNLSKIKLENEEMSKSLNISESD 1021 Query: 792 RYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKEL 851 + LE + ++ ++ + + + DEL L L ++ ++ NKE+ Sbjct: 1022 KKKLENELEENNREIENISLSLDKEISKNDELQKCLTKLSSKITDSSSRIDDLSERNKEM 1081 Query: 852 QKKNQILLEENQNLQISLSDMQQ--HYNALVEKANRTDLAESESTKYQTQLRDLESNLKR 909 ++ N+ +L+EN+ L+ L+ Q N L + N+T E K + + ++L + Sbjct: 1082 KEYNKQILQENKKLKRKLNSNSQIPDINKL-QSENKT--LSQELFKLKDENQELLERVAT 1138 Query: 910 ITHEHQTLIVQKKKEIEDLEIEF---NTQIESAIRD--KKVLNEKYEKNIEYVTQL--EA 962 +T L ++++E L +F N E I+ + K ++TQ +A Sbjct: 1139 MTLSLSQLEFEEEEETMLLSPQFDQLNNHTEEKIKSVISSPRSSKKRNRPVFLTQSLNDA 1198 Query: 963 QL-QEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINE 1010 +L E + E ++ N E +++N EL H +++ + Y Y E Sbjct: 1199 ELSSETEVKSEVISENHSEGSQIN-ELSKNHFSEEEIE--QYENSYEEE 1244 Score = 60.1 bits (139), Expect = 5e-07 Identities = 147/712 (20%), Positives = 286/712 (40%), Gaps = 69/712 (9%) Query: 92 ESLANTLKQKEILMEKIKQYKELSKRSSTTI--VRXXXXXXXXXXXXXXXQLGDV----T 145 E L +Q E LME+ + KE+ +S ++ + ++ DV Sbjct: 454 EELTQVKRQMEDLMEENENIKEILAKSVESLKKKKSEINDLKSLVENQKTEISDVEKSKE 513 Query: 146 HLSNTIKEKDNALSVLQVKMK-----------IMETTILDLQEKINE-KDQIIEAKNKAT 193 L N I+++ + L+ +++ + T+ +E+ NE + Q ++ K Sbjct: 514 ELYNEIEQQKKEIEQLKKEIERNDMNFNNYRDMSNKTLRKTEEEKNEIERQFVKYKLDTN 573 Query: 194 TXXXXXXXXXXXXXXXXXE--DTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRIS 251 T E + +++++ Q+ I M+ E + + K+ +I Sbjct: 574 TESETYKTLQTTLTDRNDEISNLRKKVSDFQKEIIKMQEEMHSKSKDFDKNKAEFTNKIK 633 Query: 252 SLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEI- 310 +LE+ N+ L + IS ++++ ++ E Q IE + EI Sbjct: 634 NLEKLNEDLRSQ--VISSQNTR--KKSEDMMEASMKQYENDILNLSQQIESNNSNHQEII 689 Query: 311 ----EEKGS----LEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSP 362 EE G+ +E ++ K+ E LE+ I E+++K + + + S Sbjct: 690 KQCKEESGNKIKEIEAEYEDKINKQKEKLENKIKDIEFQYSEIKSKYEEVNNQIQEASQM 749 Query: 363 SKK-GSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINK---NEIAKLEM---VIQ 415 + + IS T+++ S +Q+ E L + K N+ ++ K+ M +++ Sbjct: 750 KETFDNCCISLFGSIKTSNEFSSLINQMKEENLKLNELSKTNEILTGKLGKIYMANKILK 809 Query: 416 SLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDV 475 S N +L VIS + + K E+ + + +L ++ Sbjct: 810 SENANL-KNNLVISSQSSRKISDEFKNLSKKYNELNNSSENLTN-DNKTLNEKNQKLNEL 867 Query: 476 NEIAKVQEQLKQELNDEIKDVNVKDLIEK-------LKSAEEQITQLNDEIDAANKNMIK 528 N E LK +E+ N K L EK K EE +LN+E N K Sbjct: 868 NNNLS-SEFLKLSSQNEVLTNNQKILEEKHNKLQNDHKQLEENFQKLNNEHQELTTNYEK 926 Query: 529 VKSNHKLKLKQMQKTID-----NFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQL 583 + NH+ KLK+ +T + + V++ + +L +E+ +++ + E+ + L+ Sbjct: 927 LTENHE-KLKKEYETATSELSISMNDVNELTEHYKQLKDEIFNINNQYNEIISDNERLKT 985 Query: 584 HLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDK 643 L + + ES+ I++EN E K++++ ES K L EL ++ + + Sbjct: 986 EL-ELTKDELNESNNNLSKIKLEN--EEMSKSLNISESDKKKLENELEENNREIENISLS 1042 Query: 644 L-ADISQLQSDQVC---SEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDL 699 L +IS+ Q C K +ID LS KE+ + + + ++L + Sbjct: 1043 LDKEISKNDELQKCLTKLSSKITDSSSRIDDLSERNKEMKEYNKQILQENKKLKRKLN-- 1100 Query: 700 ENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQF 751 N + +NKLQ+ EN L+ +L K+ E ELL ++ S Q +F Sbjct: 1101 SNSQIPDINKLQS---ENKTLSQELFKLKDEN-QELLERVATMTLSLSQLEF 1148 >UniRef50_A0D2T6 Cluster: Chromosome undetermined scaffold_35, whole genome shotgun sequence; n=1; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_35, whole genome shotgun sequence - Paramecium tetraurelia Length = 1023 Score = 132 bits (319), Expect = 8e-29 Identities = 178/898 (19%), Positives = 397/898 (44%), Gaps = 65/898 (7%) Query: 734 ELLAKINHEEQSKIQTQFGIDAKIQE--RDLYIENI----ESELSKYKSRICRLEES--- 784 EL +IN E KI G +Q+ + L IEN ++E+ + K LE Sbjct: 66 ELQFQINAGELKKIDYLEGRIKVLQDAVKQLNIENRSQINQNEILRVKCDELELENQDLK 125 Query: 785 IAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEI 844 +A +E++R L D L + ++ + Y Q +L + V+ + + + L+EI Sbjct: 126 MARLENKR--LRELLDGAHDELSQAKQTIANYEDQLADLAIKDQVIKEQKDKINQLLVEI 183 Query: 845 EHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLE 904 E K Q+ + ++ + + S ++ N+ + R+ +++ YQ +L++L Sbjct: 184 EFWKKRYQQLDTDRIKGIEEFKKSSETLR---NSQFNELRRSGSMQAQG--YQNELKNLR 238 Query: 905 SNLKRITHEHQTLI-----VQKKKEIEDLEI-EFNTQIESAIRDKKVLNEKYEKNIEYVT 958 L+R+ E+ L ++ K ++ + E NT++ES+ ++ K LN+ + + Sbjct: 239 VQLERLQQENNELKDNIHQLESSKNGQNSQFKEVNTKLESSTKEIKRLNDILLQRGQQNK 298 Query: 959 QLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALL 1018 QLE +++E + + N+ EE++K+ +L DK+ KQ + + Q N I +L LL Sbjct: 299 QLELRIKELERQVSEKNILKEEIDKLKQQLNDKN--KQLQEQHNQITQLNNRIAELERLL 356 Query: 1019 KQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHN 1078 Q+ ++ Q++ +++ + ++A K+EN+ ++++ + K + + Sbjct: 357 -QESKQYKEKIQQLQTEIAQLKAIIQGKDEEIAILKQKIENLTDQLKEIDKIIQEKYALE 415 Query: 1079 EELQILVREQDDQIKELKETKLTF-EMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXX 1137 ++ +L E + + +LK + T E+ + + +E + D + + Sbjct: 416 NKVAMLATEIERKAAQLKNKEKTIDELRENLDQNNHTLAEVEQLQQDIDGLHLELKGKDD 475 Query: 1138 XXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLET-LNTELTGHDVVNQEQI 1196 ++E ++ E QEQ ++L T++ + K+ L + + + D ++ Sbjct: 476 L-----IKELDQKYHEALKYQEQVSQLETQVFDLQGKVAMLSSEIERQRIKLDKYKKDYD 530 Query: 1197 NQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQRE---ADFQKT 1253 Q + K+ LN + ++ + + DQ+ E + W+ L + + ++ QKT Sbjct: 531 GQ-QVKINDLNDMKFD-FDSMQDALQRYKAQEDQQQQEY-DSWRDILKKADLESSELQKT 587 Query: 1254 EHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKY 1313 + L + + +YE+L + ++ + + +E + K QD E + +Q K Sbjct: 588 QETLSSEKQIAQDQYEKLTEQIKELNKLLQEERAKIEGLHKEIEKYQDLENKVYEMQNKT 647 Query: 1314 ADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEE 1373 A + +IE R ++++ + + + + +SI +E Sbjct: 648 AMLSAEIE--RRSVKEKTKQQQFDELSQLSKQQQEDLEKMAQIEQENETLNESIKKTQDE 705 Query: 1374 NAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDE 1433 AQ++K + E KV L+ ++E + + KT E + L ++N E Sbjct: 706 IAQMQKLQDETQEKLEKVLSERGNLENKVAMLSTEIERQSYRLKNKTEECS-QLNEKNQE 764 Query: 1434 -------FENVRQQLVEYEKRIEDLTYE-KESELAILRLKMHENANHYETMQKESEIERV 1485 +++ ++ E +++E+L + E++L ++L +A +E Q E+EI++ Sbjct: 765 LQGEILKLQDLPAEVEELSQQVEELRHSLNEADLKQVKLTQDLDAVAHEKAQIEAEIQKH 824 Query: 1486 KLIEELNVKITESVSLNKQVA---ELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITN 1542 + +L ++TE KQ+A E K++EEE + +++ L +++ L +I Sbjct: 825 QDEIKLQQQLTEEA--KKQLANFTEKFKSVEEENSSLRALESKLSEYQMKTALLASQI-- 880 Query: 1543 LQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDLAMYMLHQRD 1600 A + K Q + S +Q D+ + ++ E + + EL+ + +L+++D Sbjct: 881 -----EAQNKKYQGKLDEMSALQQNFDDLKAHQLDVEDI----QGELERTLTILNEKD 929 Score = 123 bits (297), Expect = 4e-26 Identities = 177/834 (21%), Positives = 366/834 (43%), Gaps = 77/834 (9%) Query: 476 NEIAKVQEQLK--QELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKS-- 531 NE+ ++ QL+ Q+ N+E+KD N+ L Q ++N +++++ K + ++ Sbjct: 232 NELKNLRVQLERLQQENNELKD-NIHQLESSKNGQNSQFKEVNTKLESSTKEIKRLNDIL 290 Query: 532 -NHKLKLKQMQKTIDNFSK-VSDSN---KEIVRLTEELHHLSQKVAELEEEKGNLQLHLV 586 + KQ++ I + VS+ N +EI +L ++L+ ++++ E + L + Sbjct: 291 LQRGQQNKQLELRIKELERQVSEKNILKEEIDKLKQQLNDKNKQLQEQHNQITQLNNRIA 350 Query: 587 DYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLAD 646 + + + ES YK+ I+ +LKAI Q D +E+ IL+QK + + D+L + Sbjct: 351 ELER-LLQESKQYKEKIQQLQTEIAQLKAII----QGKD--EEIAILKQKIENLTDQLKE 403 Query: 647 ISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDI 706 I ++ ++ E K L +I+ +A K I+ L+ + +Q T+ ++E ++DI Sbjct: 404 IDKIIQEKYALENKVAMLATEIERKAAQLKNKEKTIDELRENLDQNNHTLAEVEQLQQDI 463 Query: 707 MNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQ-FGIDAKIQERDLYIE 765 + L ++ DL +L+ +K E L E+ S+++TQ F + K+ IE Sbjct: 464 -DGLHLELKGKDDLIKELD----QKYHEALK--YQEQVSQLETQVFDLQGKVAMLSSEIE 516 Query: 766 NIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVN 825 +L KYK + I + D ++ + D L Y ++ + EY D Sbjct: 517 RQRIKLDKYKKDYDGQQVKINDLNDMKFDFDSMQDALQRYKAQEDQQQQEYDSWRD---- 572 Query: 826 RLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANR 885 +++K L E+ ELQK + L E Q Q D + +++ N+ Sbjct: 573 ----------ILKKADL----ESSELQKTQETLSSEKQIAQ----DQYEKLTEQIKELNK 614 Query: 886 TDLAESESTKYQTQLRDLE--SNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDK 943 L + E K + +++E +L+ +E Q EIE ++ T+ + + Sbjct: 615 --LLQEERAKIEGLHKEIEKYQDLENKVYEMQNKTAMLSAEIERRSVKEKTK-QQQFDEL 671 Query: 944 KVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDK--HVQKQQTQSP 1001 L+++ ++++E + Q+E + + +I+ + ++ K+ E +K V ++ Sbjct: 672 SQLSKQQQEDLEKMAQIEQENETLNESIKKTQDEIAQMQKLQDETQEKLEKVLSERGNLE 731 Query: 1002 DYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENM- 1060 + EI + + LK K EE LN+K Q + + D +++ + + ++E + Sbjct: 732 NKVAMLSTEIERQSYRLKNKTEECSQLNEKNQELQGEILKL-QDLPAEVEELSQQVEELR 790 Query: 1061 ----EEEMQRVS-KQLLDSKQHNE-ELQILVREQDDQIKELKETKLTFEMNIPKTEGMII 1114 E ++++V Q LD+ H + +++ +++ D+IK + +LT E Sbjct: 791 HSLNEADLKQVKLTQDLDAVAHEKAQIEAEIQKHQDEIK--LQQQLTEEAKKQLANFTEK 848 Query: 1115 SSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTK 1174 ++E + ++ L Q E + + + L E SA L + Sbjct: 849 FKSVEEENSSLRALESKLSEYQMKTALLASQIEAQNKKYQGKLDEMSA-LQQNFDDLKAH 907 Query: 1175 IIQLETLNTELTGHDVVNQEQINQ---LKSKLEQLNTENDNLLSTVAELRSS---ISSAV 1228 + +E + EL + E+ + K+++L + L +L S +SS V Sbjct: 908 QLDVEDIQGELERTLTILNEKDKEHGLYDKKIQELEAQIKQLEDVKYQLESKMAMVSSEV 967 Query: 1229 DQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEE 1282 ++ ++ +L K++ + + E EL +Q SK Q L+ TQ+E Sbjct: 968 ERVKYKYEKLQKEY-EENHQRLLEAEEEL-IQ----NSKEVQALEDELHHTQQE 1015 Score = 116 bits (278), Expect = 7e-24 Identities = 225/1027 (21%), Positives = 441/1027 (42%), Gaps = 115/1027 (11%) Query: 557 IVRLTEELHHLSQKVAELEEE-KGNL-QLHLVDYDSGRMIESDVYKKMIEMENLAET--- 611 I R+ EE+ K +LE + + N +L +DY GR+ K + +EN ++ Sbjct: 48 ITRMQEEIDVWRNKFFQLELQFQINAGELKKIDYLEGRIKVLQDAVKQLNIENRSQINQN 107 Query: 612 ---RLKAISL-LESQKFDLVQ-ELHILQQKYDEVEDKLADISQL---QSDQVCS-EIKSV 662 R+K L LE+Q + + E L++ D D+L+ Q DQ+ IK Sbjct: 108 EILRVKCDELELENQDLKMARLENKRLRELLDGAHDELSQAKQTIANYEDQLADLAIKDQ 167 Query: 663 HLEEQIDALSASKKELALVIENLK-LDKEQLYGTIKDLENDKEDIMN------------K 709 ++EQ D ++ E+ + + LD +++ G I++ + E + N + Sbjct: 168 VIKEQKDKINQLLVEIEFWKKRYQQLDTDRIKG-IEEFKKSSETLRNSQFNELRRSGSMQ 226 Query: 710 LQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKI--QTQFG-IDAKIQERDLYIEN 766 Q Y E +L +LE++ E +EL I+ E SK +QF ++ K++ I+ Sbjct: 227 AQGYQNELKNLRVQLERLQQEN-NELKDNIHQLESSKNGQNSQFKEVNTKLESSTKEIKR 285 Query: 767 IESELSKYKSRICRLEESIAVME---DRRYSLERKADQLGSYLQEKQKAYSEYTIQEDEL 823 + L + + +LE I +E + L+ + D+L L +K K E Q +L Sbjct: 286 LNDILLQRGQQNKQLELRIKELERQVSEKNILKEEIDKLKQQLNDKNKQLQEQHNQITQL 345 Query: 824 VNRLAVL---MDHDRVVEKQLLEIEHENKEL----QKKNQ---ILLEENQNLQISLSDMQ 873 NR+A L + + ++++ +++ E +L Q K++ IL ++ +NL L ++ Sbjct: 346 NNRIAELERLLQESKQYKEKIQQLQTEIAQLKAIIQGKDEEIAILKQKIENLTDQLKEID 405 Query: 874 QHYNALVEKANRTDLAESESTKYQTQLRDLESNL----KRITHEHQTL--IVQKKKEIED 927 + N+ + +E + QL++ E + + + + TL + Q +++I+ Sbjct: 406 KIIQEKYALENKVAMLATEIERKAAQLKNKEKTIDELRENLDQNNHTLAEVEQLQQDIDG 465 Query: 928 LEIEFNTQIESAIRDKKVLNEKYEKNIEY---VTQLEAQLQEYKNNIENLNMNVEELNKM 984 L +E + + I++ L++KY + ++Y V+QLE Q+ + + + L+ +E ++ Sbjct: 466 LHLELKGK-DDLIKE---LDQKYHEALKYQEQVSQLETQVFDLQGKVAMLSSEIER-QRI 520 Query: 985 NLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVS 1044 L+ K QQ + D + + + +AL + K +E + Q Y S Sbjct: 521 KLDKYKKDYDGQQVKINDLNDMKFDFDSMQDALQRYKAQE--------DQQQQEYDSW-- 570 Query: 1045 DYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEM 1104 K + E+Q+ + L KQ ++ + EQ IKEL KL E Sbjct: 571 ------RDILKKADLESSELQKTQETLSSEKQIAQDQYEKLTEQ---IKELN--KLLQEE 619 Query: 1105 NIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQE--QSA 1162 K EG+ IE D N V L + E ++E++ Q+ + + Sbjct: 620 RA-KIEGL--HKEIEKYQDLENKV----YEMQNKTAMLSAEIERRSVKEKTKQQQFDELS 672 Query: 1163 KLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRS 1222 +L+ + QE K+ Q+E N L Q++I Q++ ++ + + +LS L + Sbjct: 673 QLSKQQQEDLEKMAQIEQENETLNESIKKTQDEIAQMQKLQDETQEKLEKVLSERGNLEN 732 Query: 1223 SI---SSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQ-LSAFESKYEQLLDSVQSS 1278 + S+ ++++ + + ++ E + + L++Q L A + Q ++ ++ S Sbjct: 733 KVAMLSTEIERQSYRLKNKTEECSQLNEKNQELQGEILKLQDLPAEVEELSQQVEELRHS 792 Query: 1279 TQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXX 1338 E K V + Q L +K + +Q K+ D I + L E + + F Sbjct: 793 LNEADLKQVKLTQ--DLDAVAHEKAQIEAEIQ-KHQDEIKLQQQLTEEAKKQLANFTEKF 849 Query: 1339 XXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDA 1398 LR + Q ++ L ++ AQ KK +D Sbjct: 850 KSVEEENSS----LRALESKLSEYQMKTALLASQIEAQNKKYQGKLDEMSALQQ-NFDDL 904 Query: 1399 EAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDE----FENVRQQLVEYEKRIEDLTYE 1454 +A HQL+++D Q E T+T+ D+ ++ Q+L K++ED+ Y+ Sbjct: 905 KA------HQLDVED---IQGELERTLTILNEKDKEHGLYDKKIQELEAQIKQLEDVKYQ 955 Query: 1455 KESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEE 1514 ES++A++ ++ YE +QKE E +L+E I S + EL+ ++ Sbjct: 956 LESKMAMVSSEVERVKYKYEKLQKEYEENHQRLLEAEEELIQNSKEVQALEDELHHT-QQ 1014 Query: 1515 EVAKTNE 1521 E+A++ + Sbjct: 1015 ELAQSRK 1021 Score = 108 bits (260), Expect = 1e-21 Identities = 199/916 (21%), Positives = 407/916 (44%), Gaps = 96/916 (10%) Query: 215 KQQMTKMQENFIAMEAEWKDEKQRLLKD-IES-KDVRISSLEEANKLLEAARFEISLEHS 272 K+Q K+ + + +E WK Q+L D I+ ++ + SS N R S++ Sbjct: 170 KEQKDKINQLLVEIEF-WKKRYQQLDTDRIKGIEEFKKSSETLRNSQFNELRRSGSMQAQ 228 Query: 273 KLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLE 332 EL+ L K +I K + + TK+I+ L Sbjct: 229 GYQNELKNLRVQLERLQQENNEL-KDNIHQLESSKNGQNSQFKEVNTKLESSTKEIKRLN 287 Query: 333 HLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSE 392 + Q Q NK+LE ++ + + VS + + K N +K QL E Sbjct: 288 DILLQRGQQNKQLELRIKEL---ERQVSEKNILKEEIDKLKQQLNDKNK------QL-QE 337 Query: 393 TLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQL 452 NQ T ++N N IA+LE ++Q +K +K I + T GKD IA L Sbjct: 338 QHNQIT--QLN-NRIAELERLLQE-SKQYKEK---IQQLQTEIAQLKAIIQGKDEEIAIL 390 Query: 453 QLEHQQHMEGPSLIHVGTNTEDVNEIAK-VQEQLKQELNDEIKDVNVKDLIEKLKSAEEQ 511 +Q +E T+ + EI K +QE+ E + ++ +LK+ E+ Sbjct: 391 ----KQKIE--------NLTDQLKEIDKIIQEKYALENKVAMLATEIERKAAQLKNKEKT 438 Query: 512 ITQLNDEIDAANKNMIKVKSNHKL-KLKQMQKTIDNFSKVSDSNKEIVRLTEELHH---- 566 I +L + +D ++NH L +++Q+Q+ ID ++++ ++ +H Sbjct: 439 IDELRENLD---------QNNHTLAEVEQLQQDIDGLHLELKGKDDLIKELDQKYHEALK 489 Query: 567 LSQKVAELEEEKGNLQLHLVDYDS---GRMIESDVYKK-----MIEMENLAETRLKAISL 618 ++V++LE + +LQ + S + I+ D YKK +++ +L + + S+ Sbjct: 490 YQEQVSQLETQVFDLQGKVAMLSSEIERQRIKLDKYKKDYDGQQVKINDLNDMKFDFDSM 549 Query: 619 LESQKFDLVQELHILQQKYDEVED--KLADI--SQLQSDQVCSEIKSVHLEEQIDALSAS 674 ++ + QE QQ+YD D K AD+ S+LQ Q + ++Q + L+ Sbjct: 550 QDALQRYKAQE-DQQQQEYDSWRDILKKADLESSELQKTQETLSSEKQIAQDQYEKLTEQ 608 Query: 675 KKELALVIENLKLDKEQLYGTI---KDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEK 731 KEL +++ + E L+ I +DLEN ++ NK + ++ EK ++ Sbjct: 609 IKELNKLLQEERAKIEGLHKEIEKYQDLENKVYEMQNKTA-MLSAEIERRSVKEKTKQQQ 667 Query: 732 ISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDR 791 E L++++ ++Q ++ I+ + + + I+ + E+++ + +E + + Sbjct: 668 FDE-LSQLSKQQQEDLEKMAQIEQENETLNESIKKTQDEIAQMQKLQDETQEKLEKVLSE 726 Query: 792 RYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKEL 851 R +LE K L + ++ + T + +L + L ++ E+E ++++ Sbjct: 727 RGNLENKVAMLSTEIERQSYRLKNKTEECSQLNEKNQELQGEILKLQDLPAEVEELSQQV 786 Query: 852 QKKNQILLEENQNLQISLSDMQQHYNALV-EKANRTDLAESESTKYQTQLRDLESNLKRI 910 ++ L E + Q+ L+ Q +A+ EKA E+E K+Q +++ L+ L Sbjct: 787 EELRHSLNEADLK-QVKLT---QDLDAVAHEKAQ----IEAEIQKHQDEIK-LQQQLTEE 837 Query: 911 THEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNN 970 + +K K +E E N+ + A+ K L+E K +Q+EAQ ++Y+ Sbjct: 838 AKKQLANFTEKFKSVE----EENSSLR-ALESK--LSEYQMKTALLASQIEAQNKKYQGK 890 Query: 971 IEN---LNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIA 1027 ++ L N ++L L++ D + ++T + +NE +K + L +K +E+ A Sbjct: 891 LDEMSALQQNFDDLKAHQLDVEDIQGELERTLT------ILNEKDKEHGLYDKKIQELEA 944 Query: 1028 LNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSK----QHNEELQI 1083 +++ + + S ++ S++ + K E +++E + ++LL+++ Q+++E+Q Sbjct: 945 QIKQLEDVKYQLESKMAMVSSEVERVKYKYEKLQKEYEENHQRLLEAEEELIQNSKEVQA 1004 Query: 1084 LVREQDDQIKELKETK 1099 L E +EL +++ Sbjct: 1005 LEDELHHTQQELAQSR 1020 Score = 84.6 bits (200), Expect = 2e-14 Identities = 154/779 (19%), Positives = 332/779 (42%), Gaps = 75/779 (9%) Query: 229 EAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXX 288 E E + ++ +LK E D L + NK L+ +I+ ++++A ELE+ Sbjct: 306 ELERQVSEKNILK--EEIDKLKQQLNDKNKQLQEQHNQITQLNNRIA-ELERLLQE---- 358 Query: 289 XXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENK 348 +KQ E + +TEI + ++ E+ + +E+L Q+++ +K ++ K Sbjct: 359 -------SKQYKEKIQQLQTEIAQLKAIIQGKDEEIAILKQKIENLTDQLKEIDKIIQEK 411 Query: 349 LATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIA 408 A + + +K + L K+ T +++ E L+Q+ E+ Sbjct: 412 YALENKVAMLATEIERKAAQL---KNKEKTIDELR--------ENLDQNNH---TLAEVE 457 Query: 409 KLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQL-QLEHQQHMEGPSLIH 467 +L+ I L+ +L K+ +I E D L Q+ L+ + M + Sbjct: 458 QLQQDIDGLHLELKGKDDLIKELDQKYHEALKYQEQVSQLETQVFDLQGKVAMLSSEIER 517 Query: 468 VGTNTEDVNEIAKVQEQLKQELNDEIKDV-NVKDLIEKLKSAEEQITQLNDEIDAANKNM 526 + + Q+ +LND D +++D +++ K+ E+Q Q E D+ +++ Sbjct: 518 QRIKLDKYKKDYDGQQVKINDLNDMKFDFDSMQDALQRYKAQEDQQQQ---EYDSW-RDI 573 Query: 527 IKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLV 586 +K +L++ Q+T+ + +++ E +LTE++ L++ L+EE+ ++ Sbjct: 574 LKKADLESSELQKTQETLSSEKQIAQDQYE--KLTEQIKELNKL---LQEERAKIEGLHK 628 Query: 587 DYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLAD 646 + + + +E+ VY +M + ++ S+ E K EL L ++ E +K+A Sbjct: 629 EIEKYQDLENKVY-EMQNKTAMLSAEIERRSVKEKTKQQQFDELSQLSKQQQEDLEKMAQ 687 Query: 647 ISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDI 706 I Q +++ + IK +++I + + E +E + ++ L + L + E Sbjct: 688 IEQ-ENETLNESIKKT--QDEIAQMQKLQDETQEKLEKVLSERGNLENKVAMLSTEIERQ 744 Query: 707 MNKLQNYIQENMDLTDKLEKMSAE--KISELLAKINHEEQSKIQTQFGIDAKIQERDLYI 764 +L+N +E L +K +++ E K+ +L A++ Q + + ++ E DL Sbjct: 745 SYRLKNKTEECSQLNEKNQELQGEILKLQDLPAEVEELSQQVEELRHSLN----EADLKQ 800 Query: 765 ENIESELSKYKSRICRLEESIAVMEDR---RYSLERKADQLGSYLQEKQKAYSEYTIQED 821 + +L ++E I +D + L +A + + EK K+ E Sbjct: 801 VKLTQDLDAVAHEKAQIEAEIQKHQDEIKLQQQLTEEAKKQLANFTEKFKSVEEENSSLR 860 Query: 822 ELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNL------QISLSDMQQH 875 L ++L+ ++ Q IE +NK+ Q K + QN Q+ + D+Q Sbjct: 861 ALESKLSEYQMKTALLASQ---IEAQNKKYQGKLDEMSALQQNFDDLKAHQLDVEDIQGE 917 Query: 876 YNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQ 935 + N D E Y ++++LE+ +K++ K ++E +++ Sbjct: 918 LERTLTILNEKD---KEHGLYDKKIQELEAQIKQLE--------DVKYQLESKMAMVSSE 966 Query: 936 IESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQ 994 +E + L ++YE+N + + + E +L + ++ L +EL+ EL Q Sbjct: 967 VERVKYKYEKLQKEYEENHQRLLEAEEELIQNSKEVQALE---DELHHTQQELAQSRKQ 1022 >UniRef50_UPI0000E47346 Cluster: PREDICTED: similar to Golgi-associated microtubule-binding protein isoform 3, partial; n=2; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to Golgi-associated microtubule-binding protein isoform 3, partial - Strongylocentrotus purpuratus Length = 2147 Score = 132 bits (318), Expect = 1e-28 Identities = 252/1412 (17%), Positives = 568/1412 (40%), Gaps = 113/1412 (8%) Query: 162 QVKMKIMETTILDLQEKINEKDQIIE--AKNKATTXXXXXXXXXXXXXXXXXEDTKQQMT 219 +++ + +E ++ +++++ EKD+I++ K +D + Sbjct: 593 EMEKQALEEVVIRMRDQLKEKDRILQDMTAEKGLMAVHKEHSEDLEEKVKTLQDNNASLL 652 Query: 220 KMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELE 279 K +E + E ++ +R+ + D IS + +A LE E+ +S + +++E Sbjct: 653 KEKETAKRVNEEMAEKLKRIEGEKNDLDASISQITKAKDGLENRLHEVESRYSAIEEDME 712 Query: 280 QXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIE-EKGSLEIANMTELTKKIELLEHLNCQI 338 +Q + + EEK ++E + L+ + T L + I + L +I Sbjct: 713 TSRGDM-----------EQELNRTREEKEQLETDLNQLDAQHQTALEQIISSRDKLIQEI 761 Query: 339 RQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDT 398 KE E+++ + K ++ + + + +M+ S ++ L+ + Sbjct: 762 ----KEKESQI--IDVNDKLAKQSAELEQSAADKAALEDEMEEMREDLSTSRADLLDSEQ 815 Query: 399 DKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQ 458 K+ + L +Q++ E+ S K+ G ++ ++E Q+ Sbjct: 816 MKQEQAVAMTTLRTKLQAMQD-----EHNESLKEFDEFRRESQLNGGGLAASKQEVEKQR 870 Query: 459 HMEGPSL-IHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLND 517 + L ++ ++ K+Q +E + +V L +L +I +LN Sbjct: 871 QADETDLPSREALQSQILDLTEKLQSLQSKEQSGVSPTESVAYLEHELSRTHHEIEELNK 930 Query: 518 EIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEE 577 ID + + ++ SNH K++++ + + N+ R+ EE+ + + E Sbjct: 931 SIDERDAKLQEMNSNHSEHSKRLEQKAAEVTALETENE---RIQEEVKSRDEVLTRSHSE 987 Query: 578 KGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISL-LESQKFDLVQELHILQQK 636 LQ L SG + ++ + + +S+ L S+K L + ++ Sbjct: 988 LMKLQADLAAIKSGAERRENAQEQERTLAEQLQKTCDGLSVELNSKKELLESVIESKKEL 1047 Query: 637 YDEVEDKLADISQLQSDQVCSEIKSVHL-EEQIDALSASKKELALVIENLKLDKEQLYGT 695 D +E K D+ L +D+ K+V +++I L+A KE+ V L+ KE Sbjct: 1048 EDLIEQKEEDVRAL-ADENTHYFKNVEKSKDKIGELTAKVKEMENVDRQLQETKENFEKL 1106 Query: 696 IKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDA 755 +LE K ++ +K+ + +E+++ T L K + + LA+ H+E + ++ + + Sbjct: 1107 TGELERTKSEL-SKMSSSGEEHLETTHTL-KEEVNNLKKNLAQ--HQESTGVEKE-NLQT 1161 Query: 756 KIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSE 815 K E ++ ++S+ + E ++ ++ S+++ + L E + + Sbjct: 1162 KEDELTEELKESTQKISELNEELHAAELELSGVQAELESVQKTMAAQETQLSESNERINV 1221 Query: 816 YTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQH 875 + +L +++ L D +V E ++ +L +K+ I+ E + L++S + ++ Sbjct: 1222 KEAEISQLKSQIESLRDQSKVDESSADAVDQLQTDLIEKSAIINELQKELEVSRAGLESQ 1281 Query: 876 YNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQ 935 E D S TQLR+ +KK +++ +E+ +Q Sbjct: 1282 LQTFQESIQNKDNEISRLDSSLTQLRN------------------QKKSLDESLVEYESQ 1323 Query: 936 IESAIRDKKVLNEKYEKNIEYVTQLEAQLQE-YKNNIENLNMNVEELNKMNLELIDKH-V 993 IE R +E + E V + QLQ+ K ++N MN+ ++ L Sbjct: 1324 IEDLQRTNLQKDEDVNRLREEVGNITTQLQQPAKQPLQNGEMNISVSERIEDALPPSSPF 1383 Query: 994 QKQQTQSPDYTEQYINEINK-LNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQ 1052 K T + I++ K +++++++EI L + + S ++ +S+ +S Sbjct: 1384 SKSPTGVFQGQDGSISDNEKHYEKIIQEREKEISMLQHE----RQSLLTSLSE-KSTSTM 1438 Query: 1053 FTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKET--KLTFEMNIPKTE 1110 + L ++ + +V + L+S++H ++ ++ E+ + LK KL ++ K Sbjct: 1439 GNSVLVDLHKNQMKV--KTLESERH--QMMTVLNEKTREASNLKNEVHKLVKVISAQK-- 1492 Query: 1111 GMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQE 1170 S +E +D + + IQ++ + E + NT L Sbjct: 1493 -----SALEKAQEDVKELHNASRGPRDDMQKEALHNLSRIIQDKDLEIEALKQKNTSL-- 1545 Query: 1171 CYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQ 1230 LE L +E N QI+ + S+ E+L EN L +L SI Q Sbjct: 1546 -------LEVLQSEAPS----NSSQISGVLSESEKLQKENTVLKEERDQLVVSIHQK-HQ 1593 Query: 1231 RGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQE--ETNKIV- 1287 E ++ + + QK +L A +SK ++L +S+ S E E++++ Sbjct: 1594 ESLAYYEEVQRLVGIVNGEVQK-HSDLEKHHGALQSKMDELTESMNQSKMELNESSRVTG 1652 Query: 1288 TMEQVTSLQNKL-QDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXX 1346 ++E+ +Q +L ++ E ++ L + ++ ++E L ++E K Sbjct: 1653 SLEEELEIQKQLVEELENQVQLLDDSGTEMTKRMEELE-KLEASKTNELGEKENELAHLQ 1711 Query: 1347 XXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELT 1406 +L+T + E++++ QL + D +++ Sbjct: 1712 HMLDELKTRRAP---IIEETVVKAEMAPVQLSAPPVQYEQKMQEKDAEIADLRSRLQPQQ 1768 Query: 1407 HQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESE-LAILRLK 1465 ++ + + K H+ + + D+ E+ L+E + ++D + E E + L I L+ Sbjct: 1769 VTPQVSEDMVSLKEHDGELASVK--DQLESQGHALLEMDGLVKDRSMELEQKKLEIATLR 1826 Query: 1466 MHENANHYETMQKESEIER-VKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQT 1524 + + + + +++ +++L+V L + E N T ++ Sbjct: 1827 QQIDQQDQAILDQNATLQKHTSDLQQLHV------DLKAKTEEANTLRHH----TQQISM 1876 Query: 1525 ALENQEIEIVTLNDEITNLQNMVRASSSKIQK 1556 L+ E E+ + EITN Q+MV ++++ Sbjct: 1877 RLQAVEQELARAHQEITNQQHMVLNKDGELRQ 1908 Score = 109 bits (263), Expect = 5e-22 Identities = 222/1182 (18%), Positives = 502/1182 (42%), Gaps = 113/1182 (9%) Query: 475 VNEIAKVQEQLKQELND-EIKDVNVKDLIEKLKS-AEEQITQLNDEIDAANKNMIKVKSN 532 +++I K ++ L+ L++ E + +++ +E + E+++ + +E + ++ ++ + Sbjct: 683 ISQITKAKDGLENRLHEVESRYSAIEEDMETSRGDMEQELNRTREEKEQLETDLNQLDAQ 742 Query: 533 HKLKLKQMQKTIDNF--------SKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLH 584 H+ L+Q+ + D S++ D N ++ + + EL + A LE+E ++ Sbjct: 743 HQTALEQIISSRDKLIQEIKEKESQIIDVNDKLAKQSAELEQSAADKAALEDEMEEMRED 802 Query: 585 LVDYDSGRMIESDVYKK--MIEMENLAETRLKAI------SLLESQKFDLVQELH---IL 633 L +++S+ K+ + M L T+L+A+ SL E +F +L+ + Sbjct: 803 L-STSRADLLDSEQMKQEQAVAMTTL-RTKLQAMQDEHNESLKEFDEFRRESQLNGGGLA 860 Query: 634 QQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLY 693 K + + + AD + L S + + + L E++ +L + ++ E++ + +L Sbjct: 861 ASKQEVEKQRQADETDLPSREALQS-QILDLTEKLQSLQSKEQSGVSPTESVAYLEHELS 919 Query: 694 GT---IKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQ 750 T I++L ++ KLQ + + + +LE+ +AE + L N Q +++++ Sbjct: 920 RTHHEIEELNKSIDERDAKLQEMNSNHSEHSKRLEQKAAEVTA--LETENERIQEEVKSR 977 Query: 751 FGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQ 810 D + + ++++L+ KS R E + L++ D L L K+ Sbjct: 978 ---DEVLTRSHSELMKLQADLAAIKSGAERRENAQEQERTLAEQLQKTCDGLSVELNSKK 1034 Query: 811 KAYSEYTIQEDELVNRLAVLMDHDRVV-EKQLLEIEHENKELQKKNQIL--LEENQNLQI 867 + + EL + + + R + ++ ++ K K ++ ++E +N+ Sbjct: 1035 ELLESVIESKKELEDLIEQKEEDVRALADENTHYFKNVEKSKDKIGELTAKVKEMENVDR 1094 Query: 868 SLSDMQQHYNALVEKANRTD-----LAESESTKYQTQ--LRDLESNLKRITHEHQTLIVQ 920 L + ++++ L + RT ++ S +T L++ +NLK+ +HQ Sbjct: 1095 QLQETKENFEKLTGELERTKSELSKMSSSGEEHLETTHTLKEEVNNLKKNLAQHQESTGV 1154 Query: 921 KKKEIEDLEIEFNTQIESAIRDKKVLNEKY----------EKNIEYVTQ-LEAQLQEYKN 969 +K+ ++ E E +++ + + LNE+ + +E V + + AQ + Sbjct: 1155 EKENLQTKEDELTEELKESTQKISELNEELHAAELELSGVQAELESVQKTMAAQETQLSE 1214 Query: 970 NIENLNMNVEELNKMNLELIDKHVQ-KQQTQSPDYTEQYINEINKLNALLKQKDEEIIAL 1028 + E +N+ E++++ ++ Q K S D +Q ++ + +A++ + +E+ Sbjct: 1215 SNERINVKEAEISQLKSQIESLRDQSKVDESSADAVDQLQTDLIEKSAIINELQKELEVS 1274 Query: 1029 NQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQ 1088 + + ++ + + ++++++ + L + + + + + L++ + E+LQ ++ Sbjct: 1275 RAGLESQLQTFQESIQNKDNEISRLDSSLTQLRNQKKSLDESLVEYESQIEDLQRTNLQK 1334 Query: 1089 DDQIKELKET--KLTFEMNIPKTE-------GMIISSTIE---PMSDDANNVDXXXXXXX 1136 D+ + L+E +T ++ P + + +S IE P S + Sbjct: 1335 DEDVNRLREEVGNITTQLQQPAKQPLQNGEMNISVSERIEDALPPSSPFSKSPTGVFQGQ 1394 Query: 1137 XXXXXLKVQEEEEFIQER----SVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVN 1192 + E+ IQER S+LQ + L T L E T + L V Sbjct: 1395 DGSISDNEKHYEKIIQEREKEISMLQHERQSLLTSLSEKSTSTMGNSVLVDLHKNQMKVK 1454 Query: 1193 --QEQINQLKSKLEQLNTENDNLLSTVAELRSSIS---SAVDQRGFEIAELWKQHLAQRE 1247 + + +Q+ + L + E NL + V +L IS SA+++ ++ EL R+ Sbjct: 1455 TLESERHQMMTVLNEKTREASNLKNEVHKLVKVISAQKSALEKAQEDVKELHNASRGPRD 1514 Query: 1248 ADFQKTE-HELR-------VQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKL 1299 D QK H L +++ A + K LL+ +QS +++I V S KL Sbjct: 1515 -DMQKEALHNLSRIIQDKDLEIEALKQKNTSLLEVLQSEAPSNSSQI---SGVLSESEKL 1570 Query: 1300 QDKEEHLRNLQEKYADVINQI--EILRSEIEDEK-VAFXXXXXXXXXXXXXXXXDLRTEN 1356 Q + L+ +++ I+Q E L E ++ V L+++ Sbjct: 1571 QKENTVLKEERDQLVVSIHQKHQESLAYYEEVQRLVGIVNGEVQKHSDLEKHHGALQSKM 1630 Query: 1357 QSYKQMQEQSILNINEEN---AQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKD 1413 + QS + +NE + L++ +V + E+T ++E + Sbjct: 1631 DELTESMNQSKMELNESSRVTGSLEEELEIQKQLVEELENQVQLLDDSGTEMTKRMEELE 1690 Query: 1414 SEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEK--ESELAILRLKMHENAN 1471 KT+E L ++ +E +++ L E + R + E ++E+A ++L Sbjct: 1691 KLEASKTNE----LGEKENELAHLQHMLDELKTRRAPIIEETVVKAEMAPVQLSAPPVQY 1746 Query: 1472 HYETMQKESEIE--RVKLI-EELNVKITES-VSLNKQVAEL----------NKALEEEVA 1517 + +K++EI R +L +++ +++E VSL + EL AL E Sbjct: 1747 EQKMQEKDAEIADLRSRLQPQQVTPQVSEDMVSLKEHDGELASVKDQLESQGHALLEMDG 1806 Query: 1518 KTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVS 1559 + LE +++EI TL +I + ++ +QKH S Sbjct: 1807 LVKDRSMELEQKKLEIATLRQQIDQQDQAILDQNATLQKHTS 1848 Score = 102 bits (245), Expect = 7e-20 Identities = 198/1012 (19%), Positives = 422/1012 (41%), Gaps = 76/1012 (7%) Query: 146 HLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXX 205 HL T K+ ++ + + E+T ++ + ++D++ E + K +T Sbjct: 1127 HLETTHTLKEEVNNLKKNLAQHQESTGVEKENLQTKEDELTE-ELKESTQKISELNEELH 1185 Query: 206 XXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRL-LKDIESKDVR--ISSLEEANKLLEA 262 + ++ +Q+ A E + + +R+ +K+ E ++ I SL + +K+ E+ Sbjct: 1186 AAELELSGVQAELESVQKTMAAQETQLSESNERINVKEAEISQLKSQIESLRDQSKVDES 1245 Query: 263 ARFEIS------LEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIE----- 311 + + +E S + EL++ ++SI+ E + ++ Sbjct: 1246 SADAVDQLQTDLIEKSAIINELQKELEVSRAGLESQLQTFQESIQNKDNEISRLDSSLTQ 1305 Query: 312 ---EKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTE-SKAVSSPSKKGS 367 +K SL+ ++ E +IE L+ N Q + L ++ + T+ + P + G Sbjct: 1306 LRNQKKSLD-ESLVEYESQIEDLQRTNLQKDEDVNRLREEVGNITTQLQQPAKQPLQNGE 1364 Query: 368 PLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYV 427 IS A SP+S+ S + Q D I+ NE E +IQ K++ ++ Sbjct: 1365 MNISVSERIEDALPPSSPFSK-SPTGVFQGQDGSISDNE-KHYEKIIQEREKEISMLQHE 1422 Query: 428 ISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDV-NEIAKVQEQLK 486 T G L+ H+ M+ +L V NE + LK Sbjct: 1423 RQSLLTSLSEKSTSTMGNSVLVDL----HKNQMKVKTLESERHQMMTVLNEKTREASNLK 1478 Query: 487 QELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDN 546 E++ +K ++ + L+ A+E + +L++ +M K ++ H L K ++ Sbjct: 1479 NEVHKLVKVISAQK--SALEKAQEDVKELHNASRGPRDDMQK-EALHNLSRIIQDKDLE- 1534 Query: 547 FSKVSDSNKEIVR-LTEELHHLSQKVAELEEEKGNLQLH--LVDYDSGRMIESDVYKKMI 603 + N ++ L E S +++ + E LQ ++ + +++ S K Sbjct: 1535 IEALKQKNTSLLEVLQSEAPSNSSQISGVLSESEKLQKENTVLKEERDQLVVSIHQKHQE 1594 Query: 604 EMENLAET-RLKAISLLESQKFDLVQELH-ILQQKYDEVEDKLADISQLQSDQVCSEIKS 661 + E RL I E QK +++ H LQ K DE+ + + S+++ ++ S + Sbjct: 1595 SLAYYEEVQRLVGIVNGEVQKHSDLEKHHGALQSKMDELTESMNQ-SKMELNE--SSRVT 1651 Query: 662 VHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKL---QNYIQENM 718 LEE+++ +EL ++ L ++ +++LE + N+L +N + Sbjct: 1652 GSLEEELEIQKQLVEELENQVQLLDDSGTEMTKRMEELEKLEASKTNELGEKENELAHLQ 1711 Query: 719 DLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRI 778 + D+L+ A I E + K + K+QE+D +E++ +SR+ Sbjct: 1712 HMLDELKTRRAPIIEETVVKAEMAPVQLSAPPVQYEQKMQEKD-------AEIADLRSRL 1764 Query: 779 CRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVE 838 + + V ED SL+ +L S ++++ ++ ++ D LV D +E Sbjct: 1765 QPQQVTPQVSEDM-VSLKEHDGELAS-VKDQLESQGHALLEMDGLVK------DRSMELE 1816 Query: 839 KQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQT 898 ++ LEI +++ +++Q +L++N LQ SD+QQ + L K + + + Sbjct: 1817 QKKLEIATLRQQIDQQDQAILDQNATLQKHTSDLQQLHVDLKAKTEEANTLRHHTQQISM 1876 Query: 899 QLRDLESNLKRITHE---HQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIE 955 +L+ +E L R E Q +++ K E+ L+ + +++ + +R EK+ E Sbjct: 1877 RLQAVEQELARAHQEITNQQHMVLNKDGELRQLQ-DLMSRMSAEVR---------EKDFE 1926 Query: 956 YVTQLEAQLQEYKNNIENLNMNVE-ELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKL 1014 +T L + + +++ + +V+ E+ ++ E Q Q+ Q E + Sbjct: 1927 -LTALRDKCKTLAKLVDDKDTDVQGEVRRLLGEAEAMQTQAQRFQQERDQAMMALEKCQR 1985 Query: 1015 NALLKQKDEEIIALN-QKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQ-RVSKQLL 1072 + LL Q++ + N QK+ + + E Q + E E+E++ R+S Sbjct: 1986 DLLLLQEEAAMRGGNEQKLMRELERLRNHLIQMEDTYTQEALQAEEREKELRNRLSMAEE 2045 Query: 1073 DSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDD 1124 + + +Q + +E QI L++ MN K ++ S ++ S++ Sbjct: 2046 HAHSSSSAVQSVSKEASAQIDSLQDQ--LGAMNEQKDHALMQLSMVQSESEE 2095 Score = 98.3 bits (234), Expect = 2e-18 Identities = 226/1197 (18%), Positives = 483/1197 (40%), Gaps = 116/1197 (9%) Query: 483 EQLKQELNDEIKDVNVKDL--IEKLKS----AEEQITQLNDE--IDAANKNMIK--VKSN 532 E L LN ++K+++ +D E+ S +E ++T + E +D+ + ++ V+ Sbjct: 438 EALITNLNQKVKELSGQDPQGSEQRPSDPSQSESELTLVTGESDLDSLPQGGVEDGVQVR 497 Query: 533 HKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNL--QLHLVDYDS 590 + ++ Q D+ S SD + + LS L E K +L V +D Sbjct: 498 RHISYRRPQSPTDS-SVASDLSSSVREGWTSETELSSDGGFLTEGKQSLLENSDAVSFD- 555 Query: 591 GRMIESDVYKKMIE-MENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQ 649 G +S ++ + E A+ + ++ E + D E L++ + D+L + + Sbjct: 556 GEYDDSIMFAGIKEKFPEAADAFKQQLNQFEMVRADWEMEKQALEEVVIRMRDQLKEKDR 615 Query: 650 LQSDQVCSE-IKSVH------LEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLEND 702 + D + + +VH LEE++ L + L E K E++ +K +E + Sbjct: 616 ILQDMTAEKGLMAVHKEHSEDLEEKVKTLQDNNASLLKEKETAKRVNEEMAEKLKRIEGE 675 Query: 703 KEDI----------MNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFG 752 K D+ + L+N + E +E+ ++ ++N + K Q + Sbjct: 676 KNDLDASISQITKAKDGLENRLHEVESRYSAIEEDMETSRGDMEQELNRTREEKEQLETD 735 Query: 753 IDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKA 812 ++ + +E I S K I E I + D+ L +++ +L +K Sbjct: 736 LNQLDAQHQTALEQIISSRDKLIQEIKEKESQIIDVNDK---LAKQSAELEQSAADKAAL 792 Query: 813 YSEYTIQEDELVNRLAVLMDHDRVVEKQ----------LLEIEHENKELQKKNQILLEEN 862 E ++L A L+D +++ ++Q L ++ E+ E K+ E+ Sbjct: 793 EDEMEEMREDLSTSRADLLDSEQMKQEQAVAMTTLRTKLQAMQDEHNESLKEFDEFRRES 852 Query: 863 QNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKK 922 Q L+ +Q +A+ TDL E+ Q+Q+ DL L+ + + Q+ V Sbjct: 853 QLNGGGLAASKQEVEK-QRQADETDLPSREA--LQSQILDLTEKLQSLQSKEQS-GVSPT 908 Query: 923 KEIEDLEIEFN------TQIESAI--RDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENL 974 + + LE E + ++ +I RD K L E + E+ +LE + E +E Sbjct: 909 ESVAYLEHELSRTHHEIEELNKSIDERDAK-LQEMNSNHSEHSKRLEQKAAEV-TALETE 966 Query: 975 NMNVEELNKMNLELIDK-HVQKQQTQS-----PDYTEQYINEINKLNALLKQKDEEIIAL 1028 N ++E K E++ + H + + Q+ E+ N + L +Q + L Sbjct: 967 NERIQEEVKSRDEVLTRSHSELMKLQADLAAIKSGAERRENAQEQERTLAEQLQKTCDGL 1026 Query: 1029 NQKINNAQVSYMSMV---SDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILV 1085 + ++N+ + S++ + E + Q + + +E K + SK EL V Sbjct: 1027 SVELNSKKELLESVIESKKELEDLIEQKEEDVRALADENTHYFKNVEKSKDKIGELTAKV 1086 Query: 1086 REQDDQIKELKET-----KLTFEMNIPKTEGMIISS-------TIEPMSDDANNVDXXXX 1133 +E ++ ++L+ET KLT E+ K+E +SS T + ++ NN+ Sbjct: 1087 KEMENVDRQLQETKENFEKLTGELERTKSELSKMSSSGEEHLETTHTLKEEVNNLKKNLA 1146 Query: 1134 XXXXXXXXLK--VQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVV 1191 K +Q +E+ + E L+E + K++ +E + ++L + EL Sbjct: 1147 QHQESTGVEKENLQTKEDELTEE--LKESTQKISELNEELHAAELELSGVQAELESVQKT 1204 Query: 1192 NQEQINQLKSKLEQLNTENDNLLSTVAELRS-SISSAVDQRGFEIAELWKQHLAQREADF 1250 Q QL E++N + + +++ S S VD+ + + + L ++ A Sbjct: 1205 MAAQETQLSESNERINVKEAEISQLKSQIESLRDQSKVDESSADAVDQLQTDLIEKSAII 1264 Query: 1251 QKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQ 1310 + + EL V + ES+ + +S+Q+ E ++ L + L ++L Sbjct: 1265 NELQKELEVSRAGLESQLQTFQESIQNKDNE----------ISRLDSSLTQLRNQKKSLD 1314 Query: 1311 EKYADVINQIEIL-RSEIE-DEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSIL 1368 E + +QIE L R+ ++ DE V +N + I Sbjct: 1315 ESLVEYESQIEDLQRTNLQKDEDVNRLREEVGNITTQLQQPAKQPLQNGEMNISVSERIE 1374 Query: 1369 NINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLT 1428 + ++ KS ++D E ++ + E + S + + +L+ Sbjct: 1375 DALPPSSPFSKSPTGVFQGQDGS---ISDNEKHYEKIIQEREKEISMLQHERQSLLTSLS 1431 Query: 1429 QRNDEF--ENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVK 1486 +++ +V L + + +++ L E+ + +L K E +N + K VK Sbjct: 1432 EKSTSTMGNSVLVDLHKNQMKVKTLESERHQMMTVLNEKTREASNLKNEVHK-----LVK 1486 Query: 1487 LIEELNVKITESVSLNKQVAELNKALEEEVAK--TNEMQTALENQEIEIVTLNDEITNLQ 1544 +I + ++ K++ ++ +++ K + + ++++++EI L + T+L Sbjct: 1487 VISAQKSALEKAQEDVKELHNASRGPRDDMQKEALHNLSRIIQDKDLEIEALKQKNTSLL 1546 Query: 1545 NMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDLAMYMLHQRDV 1601 ++++ + +S + Q +NT+ KE R +L ++++ HQ + Sbjct: 1547 EVLQSEAPSNSSQIS--GVLSESEKLQKENTVLKE-----ERDQLVVSIHQKHQESL 1596 Score = 79.4 bits (187), Expect = 8e-13 Identities = 237/1276 (18%), Positives = 518/1276 (40%), Gaps = 152/1276 (11%) Query: 168 METTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIA 227 +++ ILDL EK+ Q E + T E+ + + + Sbjct: 883 LQSQILDLTEKLQSL-QSKEQSGVSPTESVAYLEHELSRTHHEIEELNKSIDERDAKLQE 941 Query: 228 MEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXX 287 M + + +RL E K +++LE N+ ++ E+ L + + Sbjct: 942 MNSNHSEHSKRL----EQKAAEVTALETENERIQE---EVKSRDEVLTRSHSELMKLQAD 994 Query: 288 XXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELEN 347 A++ +E+T E+ EL K ELLE + ++ KELE+ Sbjct: 995 LAAIKSG-AERRENAQEQERTLAEQLQKTCDGLSVELNSKKELLE----SVIESKKELED 1049 Query: 348 KLATMGTESKAVSSPSK---KGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINK 404 + + +A++ + K K G TA K+K E N D + K Sbjct: 1050 LIEQKEEDVRALADENTHYFKNVEKSKDKIGELTA-KVK--------EMENVDRQLQETK 1100 Query: 405 NEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHME--G 462 KL ++ +L S+ + + L+ QH E G Sbjct: 1101 ENFEKLTGELERTKSEL-------SKMSSSGEEHLETTHTLKEEVNNLKKNLAQHQESTG 1153 Query: 463 PSLIHVGTNTEDVNEIAKVQEQLKQELNDEIK--DVNVKDLIEKLKSAEEQITQLNDEID 520 ++ T +++ E K Q ELN+E+ ++ + + +L+S ++ + ++ Sbjct: 1154 VEKENLQTKEDELTEELKESTQKISELNEELHAAELELSGVQAELESVQKTMAAQETQLS 1213 Query: 521 AANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIV-RLTEELHHLSQKVAELEEE-- 577 +N+ I VK +LK +++ + SKV +S+ + V +L +L S + EL++E Sbjct: 1214 ESNER-INVKEAEISQLKSQIESLRDQSKVDESSADAVDQLQTDLIEKSAIINELQKELE 1272 Query: 578 --KGNLQLHLVDY-DSGRMIESDVYK---KMIEMENLAETRLKAISLLESQKFDL----V 627 + L+ L + +S + ++++ + + ++ N ++ +++ ESQ DL + Sbjct: 1273 VSRAGLESQLQTFQESIQNKDNEISRLDSSLTQLRNQKKSLDESLVEYESQIEDLQRTNL 1332 Query: 628 QELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKL 687 Q+ + + +EV + + Q + + ++ + E+I+ + + Sbjct: 1333 QKDEDVNRLREEVGNITTQLQQPAKQPLQNGEMNISVSERIEDALPPSSPFSKSPTGVFQ 1392 Query: 688 DKEQLYGTIKDLENDKEDIMNKLQNYIQ----ENMDLTDKLEKMSAEKISELLAKINHEE 743 ++ G+I D E E I+ + + I E L L + S + + H+ Sbjct: 1393 GQD---GSISDNEKHYEKIIQEREKEISMLQHERQSLLTSLSEKSTSTMGNSVLVDLHKN 1449 Query: 744 QSKIQT----QFGIDAKIQERDLYIENIESELSKY-------KSRICRLEESIAVMEDR- 791 Q K++T + + + E+ N+++E+ K KS + + +E + + + Sbjct: 1450 QMKVKTLESERHQMMTVLNEKTREASNLKNEVHKLVKVISAQKSALEKAQEDVKELHNAS 1509 Query: 792 ---RYSLERKA-DQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHE 847 R ++++A L +Q+K E + + + L VL Q+ + E Sbjct: 1510 RGPRDDMQKEALHNLSRIIQDKDL---EIEALKQKNTSLLEVLQSEAPSNSSQISGVLSE 1566 Query: 848 NKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANR-TDLAESESTKYQTQLRD---L 903 +++LQK+N +L EE L +S+ Q A E+ R + E K+ + L Sbjct: 1567 SEKLQKENTVLKEERDQLVVSIHQKHQESLAYYEEVQRLVGIVNGEVQKHSDLEKHHGAL 1626 Query: 904 ESNLKRIT---HEHQTLIVQKKKEIEDLEIEFNTQ---IESAIRDKKVLNE---KYEKNI 954 +S + +T ++ + + + + LE E Q +E ++L++ + K + Sbjct: 1627 QSKMDELTESMNQSKMELNESSRVTGSLEEELEIQKQLVEELENQVQLLDDSGTEMTKRM 1686 Query: 955 EYVTQLEA----QLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINE 1010 E + +LEA +L E +N + +L ++EL +I++ V K + + + Sbjct: 1687 EELEKLEASKTNELGEKENELAHLQHMLDELKTRRAPIIEETVVKAEMAPVQLSAPPVQY 1746 Query: 1011 INKLNALLKQKDEEIIALNQKINNAQVSYM---SMVS--DYESKLAQFTTKLENMEE--- 1062 K+ ++KD EI L ++ QV+ MVS +++ +LA +LE+ Sbjct: 1747 EQKM----QEKDAEIADLRSRLQPQQVTPQVSEDMVSLKEHDGELASVKDQLESQGHALL 1802 Query: 1063 EMQRVSK-QLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPM 1121 EM + K + ++ +Q E+ L ++ D Q + + + T + + + + + ++ Sbjct: 1803 EMDGLVKDRSMELEQKKLEIATLRQQIDQQDQAILDQNATLQKHTSDLQQLHVD--LKAK 1860 Query: 1122 SDDANNVDXXXXXXXXXXXXLKVQ----EEEEFIQERSVL---------QEQSAKLNTEL 1168 +++AN + ++ + +E Q+ VL Q+ ++++ E+ Sbjct: 1861 TEEANTLRHHTQQISMRLQAVEQELARAHQEITNQQHMVLNKDGELRQLQDLMSRMSAEV 1920 Query: 1169 QECYTKIIQL----ETLNTELTGHDVVNQEQINQLKSKLEQLNT-------ENDNLLSTV 1217 +E ++ L +TL + D Q ++ +L + E + T E D + + Sbjct: 1921 REKDFELTALRDKCKTLAKLVDDKDTDVQGEVRRLLGEAEAMQTQAQRFQQERDQAMMAL 1980 Query: 1218 AELR---------SSISSAVDQRGFEIAELWKQHLAQREADF-------QKTEHELRVQL 1261 + + +++ +Q+ E + HL Q E + ++ E ELR +L Sbjct: 1981 EKCQRDLLLLQEEAAMRGGNEQKLMRELERLRNHLIQMEDTYTQEALQAEEREKELRNRL 2040 Query: 1262 SAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQD----KEEHLRNLQEKYADVI 1317 S E +VQS ++E + +I +++ N+ +D + +++ E+Y + Sbjct: 2041 SMAEEHAHSSSSAVQSVSKEASAQIDSLQDQLGAMNEQKDHALMQLSMVQSESEEYILSL 2100 Query: 1318 NQIEILRSEIEDEKVA 1333 ++++ + + EK A Sbjct: 2101 GNLQMVLEQFQQEKEA 2116 >UniRef50_Q8IBY8 Cluster: Putative uncharacterized protein PF07_0042; n=1; Plasmodium falciparum 3D7|Rep: Putative uncharacterized protein PF07_0042 - Plasmodium falciparum (isolate 3D7) Length = 2910 Score = 132 bits (318), Expect = 1e-28 Identities = 252/1294 (19%), Positives = 581/1294 (44%), Gaps = 150/1294 (11%) Query: 317 EIANMTELTKKIEL-LEHLNCQIRQTNKELENKLATMGTESKAVSSPSKK--GSPLISRK 373 E+ + + K I++ LE+ Q +K++E + M + + +K + +I++ Sbjct: 1207 ELEKIKNINKNIQINLENEKKTNEQKDKQIEKQ--KMNIKEMVIQLEKEKIINNEIITQL 1264 Query: 374 SGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDT 433 +K+ + ++ LN + ++ + EM+IQ + +++ E +I ++ Sbjct: 1265 ENEKLNNKIIYEDIEKKNK-LNSELEENYENQQKKINEMIIQLEKEKIINNEIIIQLENE 1323 Query: 434 XXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEI 493 ++ I ++ E + + I+ + NE + K+ ++I Sbjct: 1324 KGSVKKINTELEN--IKKMNDEMNEKLNKEQKINNDLQLDLENEKNEKDHINKEFEKEKI 1381 Query: 494 KDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDS 553 K++ +K +++ K E LN EID + K+ + L L++ +K ID F+ ++ Sbjct: 1382 KNIQLKKNMDEEKKTNES---LNVEID----RLYKINEHVLLNLEEEKKIIDQFTIDLEN 1434 Query: 554 NKE---IVRL--TEELHHLSQKVAEL-EEEKGNLQLHLVDYDSGRMIESDVYKKMIEMEN 607 ++ I++L +E Q +L +E + N +L ++ YD G+ +++ + I++EN Sbjct: 1435 ERKRNHILQLHFDDEKKKNDQNYEDLLKEREKNKKLQIL-YDDGK---NNISQLNIDLEN 1490 Query: 608 LAETRLKAISLL---ESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQV---CSEIKS 661 TR + +L E +K + + + ++K + + + Q + +Q+ E K+ Sbjct: 1491 -ERTRNNDLKILLDQEKKKNEQINDDLENERKRNNQLQNILNEEQKKKEQLNVSYEEQKN 1549 Query: 662 VH--LEEQIDALSASKKELALVIENLKL-----------DKEQLYGTIKDLENDKEDIMN 708 ++ LE ++ + K++ E L D +Q+ T K ++ K Sbjct: 1550 INHQLENELQKQRITYKKMIAKFERKFLMKNTNDTQKIKDTQQIIDTQKIIDTQKIIDTQ 1609 Query: 709 KL---QNYIQENMDLTDKLEKMS-AEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYI 764 K+ N + + D +++M+ AE ++ E+ ++ I K ++ + Sbjct: 1610 KIIDTSNNVNQMNDEHKHVDQMNDAESEDNTFLELQLEKVKQVNIDMIIQLKKDKKRIDE 1669 Query: 765 ENIESELSKYKSR--ICRLEESIAVMEDRRYSLERKAD---QLGSYLQEKQKAYSEYTIQ 819 N+E E K + I ++EE +E LE++ + L +++ + + IQ Sbjct: 1670 LNLELEKEKEVNDKIIIQMEEYKMKIEHINEELEKEKEINHNLNIRIEKDNEKNEQLNIQ 1729 Query: 820 ---EDELVNRLAVLMDHDRVVEKQL-LEIEHENKELQKKNQILLEENQ-NLQISLSDMQQ 874 E ++ N++++ +D ++ + Q +E++ E K + N L EE + N +I++ +++ Sbjct: 1730 LDTEKKMNNQMSIELDEEKKMNHQRRIELDEEKKMNHEMNIELDEEKKINKEINIL-LEE 1788 Query: 875 HYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNT 934 + N +++ + + + QL D ++N++ + + ++ +K++ + + N Sbjct: 1789 NKNKIIQINSCLQKEKEINELLNIQLEDKKNNIQELN-----IKLEDEKKLNE---QINV 1840 Query: 935 QIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQ 994 +E+ I + + LN K E + Q+ L+ NNI+ LN+ +E+ KMN ++ ++Q Sbjct: 1841 TLENKINNIQELNIKLEDEKKLNEQINITLENKINNIQELNIKLEDEKKMNQQI---NIQ 1897 Query: 995 KQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFT 1054 ++ + N+I ++N+ LK++ E +N+++N ++ + ++ + + T Sbjct: 1898 LEEEK---------NKIIQINSHLKKEKE----INEELN-------ILLENKKNNIQEIT 1937 Query: 1055 TKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMII 1114 KL EE+ + +Q + ++ E + +V E + + E K E + + ++I Sbjct: 1938 IKL---EEQKKINEEQYIQLEKDKEIINSMVVEMEKEKIINNEIKQKLEKEKKQNDQLVI 1994 Query: 1115 SSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTK 1174 E ++ N+ ++V E+E+ I ++Q + K N E + + Sbjct: 1995 HLENEKQANKKLNILLDQNKKINEELNIQV-EQEKLINNEIIVQLK--KENEENNKINSL 2051 Query: 1175 IIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFE 1234 + + LN ++T +E+ +LK +LE EN NL + + I++ + Q E Sbjct: 2052 LEEQNGLNKKVTLQLEKEKEENGKLKLQLENEKQENGNLRFELENEKKDIANLILQLQ-E 2110 Query: 1235 IAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTS 1294 E K + Q + + +KT++ + V++ + + ++ ++ + N + +E+ + Sbjct: 2111 EKENTKNVMVQMDKEKEKTKN-VMVEMDKEKENTKNVMIELERERENNQNLNIKLEEGKN 2169 Query: 1295 LQN----KLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXX 1350 + N +L +K++ + L K + + E L+ EI++EK Sbjct: 2170 IMNQISIQLVEKQKIINQLNVKLENEKEENEKLKLEIDEEK---------------KYNK 2214 Query: 1351 DLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLE 1410 + E +S K+ E+ L I+EE + S + E++ E +L+ Sbjct: 2215 QMSVELESEKEENEKLKLEIDEEKKYNNQMSV--------------ELESE-KEENEKLK 2259 Query: 1411 LKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESE--------LAIL 1462 L+ E + ++ +I L +E E ++ ++ E +K + ++ E ESE L I Sbjct: 2260 LEIDEEKKYKNQMSIELENEKEENEKLKLEIDEEKKYNKQMSVELESEKEENEKLKLEID 2319 Query: 1463 RLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEM 1522 K + N + E K+ E E++KL E++ E +LNK + E L+ E K N++ Sbjct: 2320 EAKKYNNQMNVELESKKEENEKLKL--EID---EEKKNLNKVIYE----LDGEKIKYNDV 2370 Query: 1523 QTALENQEIEIVTLNDEITNLQNMVRASSSKIQK 1556 L+N++ ++ LN+++ N + + K+++ Sbjct: 2371 CIILDNEKNKMKELNEKLINQEKELENIKKKLEE 2404 Score = 110 bits (265), Expect = 3e-22 Identities = 219/1128 (19%), Positives = 469/1128 (41%), Gaps = 115/1128 (10%) Query: 494 KDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDS 553 K+ N+ +L ++ Q+ E++ + + N L K+++ + + SK ++ Sbjct: 861 KEDNINIPTCQLNNSTCQLNNSTCELNNSTNQLNNFIYNKDLCSKEIEDLLSDMSKYNNI 920 Query: 554 NKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRL 613 N + ++ + + + ++ N+ + L+ ++ +++Y K+ M Sbjct: 921 NVD--KIMHKYNTYNDEILLKMSNMKNVDMLLL------LLSNNIYNKI--MSTTLYNNF 970 Query: 614 KAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSA 673 I + F V ++ + + + I++ D ++ K H++ I+ + Sbjct: 971 DIIKFIMKWIFVHVIKIFVKDTYMLYINNNQGKINESNEDHNLNKNKDSHIDNNIEGENF 1030 Query: 674 SKKELALVIENLKLDKEQLYGTIK-DLENDKEDIMNKLQNYIQ--ENMDLTDKLEKMSAE 730 + L+ E + E+ IK +LEN+K I+N ++ +Q E + D + E Sbjct: 1031 LMNQ-KLIDEEV----EKRVNIIKVELENEKNIIINNIKEELQNEEKIKYNDIKTNLERE 1085 Query: 731 KISELLAKINHEEQSKIQTQFGI--DAKIQERDLYIENIESELSKYKSRICRLEESIAVM 788 K + I E++ KI + I + K + D + +E+E + K L+ + Sbjct: 1086 KKINMHMNIELEKERKINDEMMIKFEKKNKMYDDINKELENEKKQNKEIYMELQNIKNIN 1145 Query: 789 EDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHEN 848 D ++LE K+ Q + +K Y EL N+ + + + K+ + + Sbjct: 1146 SDMNFALEDKSVQYDQKCIDFEKLNKMYEDTCKELNNKNVLYEQMNTQLYKEKINNDEIC 1205 Query: 849 KELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLK 908 EL+K I N+N+QI+L + ++ N +K + Q + + +N Sbjct: 1206 TELEKIKNI----NKNIQINLEN-EKKTNEQKDKQIEKQKMNIKEMVIQLEKEKIINN-- 1258 Query: 909 RITHEHQTLIVQKKKEIEDLE--IEFNTQIESAIRD-KKVLNE---KYEKNIEYVTQLEA 962 I + + + K ED+E + N+++E + +K +NE + EK ++ Sbjct: 1259 EIITQLENEKLNNKIIYEDIEKKNKLNSELEENYENQQKKINEMIIQLEKEKIINNEIII 1318 Query: 963 QLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKD 1022 QL+ K +++ +N +E + KMN E+ +K + K+Q + D NE N+ + + K+ + Sbjct: 1319 QLENEKGSVKKINTELENIKKMNDEMNEK-LNKEQKINNDLQLDLENEKNEKDHINKEFE 1377 Query: 1023 EE---IIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNE 1079 +E I L + ++ + + S+ + + L N+EEE + + + +D + + Sbjct: 1378 KEKIKNIQLKKNMDEEKKTNESLNVEIDRLYKINEHVLLNLEEEKKIIDQFTIDLENERK 1437 Query: 1080 ELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXX 1139 IL DD E K+ +E + + E + ++ + DD N Sbjct: 1438 RNHILQLHFDD---EKKKNDQNYEDLLKEREK---NKKLQILYDDGKN--------NISQ 1483 Query: 1140 XXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQL 1199 + ++ E + +L +Q K N ++ + + N +L +++N+EQ Sbjct: 1484 LNIDLENERTRNNDLKILLDQEKKKNEQIND---DLENERKRNNQL--QNILNEEQ---- 1534 Query: 1200 KSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRV 1259 K EQLN + + +L + + IA+ ++ L + D QK + Sbjct: 1535 -KKKEQLNVSYEEQKNINHQLENELQKQRITYKKMIAKFERKFLMKNTNDTQKIKDT--- 1590 Query: 1260 QLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKL-QDKEEHLRNLQEKYADVIN 1318 +Q++D+ + +T KI+ +++ N + Q +EH K+ D +N Sbjct: 1591 ---------QQIIDTQKII---DTQKIIDTQKIIDTSNNVNQMNDEH------KHVDQMN 1632 Query: 1319 QIEILRS---EIEDEKVAFXXXXXXXXXXXXXXXXD-LRTENQSYKQMQEQSILNINEEN 1374 E + E++ EKV D L E + K++ ++ I+ + E Sbjct: 1633 DAESEDNTFLELQLEKVKQVNIDMIIQLKKDKKRIDELNLELEKEKEVNDKIIIQMEEYK 1692 Query: 1375 AQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEF 1434 +++ + +N K E QL ++ + ++ +I L + Sbjct: 1693 MKIEHIN-EELEKEKEINHNLNIRIEKDNEKNEQLNIQLDTEKKMNNQMSIELDEEKKMN 1751 Query: 1435 ENVRQQLVEYEKRIEDLTYEKESELAI---LRLKMHENANHY----ETMQKESEI----- 1482 R +L E +K ++ E + E I + + + EN N +QKE EI Sbjct: 1752 HQRRIELDEEKKMNHEMNIELDEEKKINKEINILLEENKNKIIQINSCLQKEKEINELLN 1811 Query: 1483 ----ERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALE-----NQEIEI 1533 ++ I+ELN+K+ + LN+Q+ N LE ++ E+ LE N++I I Sbjct: 1812 IQLEDKKNNIQELNIKLEDEKKLNEQI---NVTLENKINNIQELNIKLEDEKKLNEQINI 1868 Query: 1534 VTLNDEITNLQ--NMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKE 1579 TL ++I N+Q N+ K+ + ++ + ++ + Q+++ + KE Sbjct: 1869 -TLENKINNIQELNIKLEDEKKMNQQINIQLEEEKNKIIQINSHLKKE 1915 Score = 55.6 bits (128), Expect = 1e-05 Identities = 131/731 (17%), Positives = 308/731 (42%), Gaps = 53/731 (7%) Query: 306 EKTEIEEKGSLEIANMTELTKKIEL-LEHLNCQIRQTNKELENKLATMGTESKAVSSPSK 364 EK +I + ++++ N E +K++L ++ +Q + ELE++ + K Sbjct: 2180 EKQKIINQLNVKLENEKEENEKLKLEIDEEKKYNKQMSVELESEKEENEKLKLEIDEEKK 2239 Query: 365 KGSPL---ISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDL 421 + + + + N K++ + ++ + + + +NE KLE+ + Sbjct: 2240 YNNQMSVELESEKEENEKLKLEIDEEKKYKNQMSIELENEKEENEKLKLEIDEEKKYNKQ 2299 Query: 422 VDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKV 481 + E +++ K ++LE ++ + + +++N++ Sbjct: 2300 MSVELESEKEENEKLKLEIDEAKKYNNQMNVELESKKEENEKLKLEIDEEKKNLNKVIYE 2359 Query: 482 QEQLKQELND-----EIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKS-NHKL 535 + K + ND + + +K+L EKL + E+++ + +++ N K + N+K Sbjct: 2360 LDGEKIKYNDVCIILDNEKNKMKELNEKLINQEKELENIKKKLEEETLNFKKYREINYKE 2419 Query: 536 KLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIE 595 K T++N V NK + E++ L + +K + + D D M + Sbjct: 2420 KNGSNDYTMENGKNVVTRNK----INNEMNILDILDKNKKTKKTISKSNNNDNDDNNM-K 2474 Query: 596 SDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQ--LQSD 653 + Y K+ + E +K L +F+ +++ K D + K+ ++ Sbjct: 2475 DEKYNKLYY--SYVEIVIKKEEL--ENEFN--EQMKYFNDKVDIFDKKVQYFNKKITHYK 2528 Query: 654 QVCSEIKSVHLEEQIDALSASKKELALVIENLKL-DKEQLYGTIKDLENDKEDIMNKLQN 712 VC+ + +I +E+ IE + + DK L G I +++ ++I + Sbjct: 2529 NVCNMY--IKNNGKISTCIKKLEEILYSIEKVHIKDKIILDGKIYNIKIIIKEINECIHM 2586 Query: 713 YIQENMDLTDKL--EKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQE--RDLYIENIE 768 IQE D TD L +++ EK + LL KI + E+ K D+++++ ++L +NI Sbjct: 2587 KIQETED-TDVLLYDEVINEK-NILLEKILNNEKDKNIYHIEKDSELEKYMKELNFKNIN 2644 Query: 769 SELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSY------LQEKQKAYSEYTIQEDE 822 + + S L+E + + + ++E A ++ Y L ++ + + ++ Sbjct: 2645 DLFTFHLSM---LDELCIIKKCYQQAVEENAMKIKEYDNNILILNKQIELKEKKNYINEK 2701 Query: 823 LVNRLAVLMDHDRVVEKQLLE-IEHENKELQKKNQILLEENQ----NLQI-SLSDMQQHY 876 L + +D+ + + LL ++H++ + K+ + + +N+ N++I ++ + +Q+ Sbjct: 2702 NCKSLLLEVDNLKFILNDLLSYVDHKDGKRNKRQRKMSIKNELKYINMEIKNIENEEQNM 2761 Query: 877 --NALVEK-ANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFN 933 N+ +E N ++ + ++ + + ++ H+ + +K E+ D + N Sbjct: 2762 LINSEIENDGNHNEVPCAVINVHENIRNNHNRKMDNNSNIHENIETKKTLELHDSIEKMN 2821 Query: 934 TQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHV 993 T E++ LNE E N+ V L EYK N + ++ N L+++ + Sbjct: 2822 T-FENSFERNNTLNE--ENNLRNVQSLYPNFLEYKENSSFKSSTLKSNNLSELDILSNEL 2878 Query: 994 QKQQTQSPDYT 1004 T Y+ Sbjct: 2879 NSNTTSKRKYS 2889 >UniRef50_Q7RGY2 Cluster: Repeat organellar protein-related; n=3; Plasmodium (Vinckeia)|Rep: Repeat organellar protein-related - Plasmodium yoelii yoelii Length = 1441 Score = 132 bits (318), Expect = 1e-28 Identities = 272/1398 (19%), Positives = 605/1398 (43%), Gaps = 118/1398 (8%) Query: 213 DTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHS 272 D Q+ + NF E E +D+ + LK I + +++ E NK+ E E+ LE Sbjct: 7 DDDDQVRETGHNF--KEYELEDQLKETLKSITALSIKVKEYE--NKIEELEN-ELKLEKE 61 Query: 273 K-LAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTK-KIEL 330 K + +E E+ L K+ ++ +I K + + +L + E Sbjct: 62 KQINKEYEKELNEKCEFIKREMELLKEKELNINIKENKINNKEIITLKKEEKLNDIENEY 121 Query: 331 LEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRK--SGRNTASKMKSPWSQ 388 +E N + + N E+ N ++ S + K+ I++K N ++K + Sbjct: 122 IEK-NKEKEKLNYEITNIKMSLDKLSCEIQE-KKENLEKINKKVVEKENNLRELKEFMKE 179 Query: 389 LSS--ETLNQDTDKKINKNEIAKLEMVIQSLNK--DLVDKEYVISEKDTXXXXXXXXXXG 444 + E+LN+ D K KN KLE + K +++D + + EK Sbjct: 180 KNEIIESLNKTIDDK--KNAYEKLETNFEEKRKMIEMLDSKLIEKEKKFEIKKEKLEKEN 237 Query: 445 KDTLIAQLQLEH-QQHMEGPSLIHVGTNTEDVN---EIAKVQEQL-KQELNDEIKDVNVK 499 + + +E+ ++H + + +N E+ K++ L K EI + +K Sbjct: 238 EVIMEKLKDIENKEEHFKNKEEKFKNKEEKFINLENELNKLKSDLSKNACQMEIYKMEIK 297 Query: 500 DLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDS--NKEI 557 DL + L E +I ++ +E D NM +KL DN K S+ NK+I Sbjct: 298 DLSQSLVEKEREIFEIKNEYDDKINNM-----KNKLSNFNNDDNDDNTVKCSEEIINKKI 352 Query: 558 VRLTEELHHLSQKVAELEE--EKGNLQLHLVDYDSG---RMIESDVYKKMIEMENLAETR 612 +L + +K EL E +K NL++ + + + +E + K IE+ +L Sbjct: 353 EEAVNKL--IKEKEMELNEIHKKYNLEIEKIKNEINEKEKELEQNKKKHNIEINDLT--- 407 Query: 613 LKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALS 672 K I + E + D+ +E I K D ++ + +++++++ +E+ S L ++++L+ Sbjct: 408 -KEIQIREKKIEDVKEEYKIELSKLDSEKNNI----KIENNELNNEVNS--LNNEVNSLN 460 Query: 673 ASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEK---MSA 729 L I +L DK+ L K L D++N L+N I + + +K+++ M Sbjct: 461 NEVNSLNNEINSLNNDKQTLSKNNKLLN----DLINNLKNEINNSDNKMNKMKEDIIMLN 516 Query: 730 EKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVME 789 E++ I+ E+ F + K++E++ Y +++ E++ ++ I E+ M+ Sbjct: 517 EELEGKCVVIDEIEKKYKNEIFIFEKKLKEKENY-DDLNDEINILRNDISVKEKEFIEMK 575 Query: 790 DRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENK 849 + E K + +EK K Y E+EL N L + ++++ + KQ+ E+ + Sbjct: 576 E---FYENKINLYNKNFEEKTKYY------ENEL-NILRLKYNNEQDLIKQIDELNIQKL 625 Query: 850 ELQKKNQILLEENQNLQISL-SDMQQHYNALVEKANRTDLAESESTKYQTQLR---DLES 905 + ++K L ++N + S+ + + Y+ ++ ++ + E+ K++ + R + ES Sbjct: 626 KTEEKYLQLYDDNIKMFKSICAKINTTYSENIKGSDLVNFVEAY-IKHRDESRFDANSES 684 Query: 906 NLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKK--VLNEKYEKNIEYVTQLEAQ 963 +K + E L + ++E+ + E ++ + K V+ E E V E Sbjct: 685 GIKEVVAE---LEEKHREEVSRIREEHKKEVVRIGEEHKEEVVRIGEEHKEEVVKIGEQH 741 Query: 964 LQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDE 1023 +E E V ++ + + E + + ++ + + E++ E+ A L+ Sbjct: 742 REELGEKEEEHKKEVAKIGEQHKEEMVRIREEHKKEVSRIREEHKKEM----AELEDGRT 797 Query: 1024 EIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQI 1083 +++A+ ++ + +V + + +++ +++ K+E EE + VS+ ++H +E+ Sbjct: 798 DVVAVLEEEHKKEV--VRIGEEHKKEVS----KIE--EEHKKEVSRI---REEHKKEMSE 846 Query: 1084 LVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNV---DXXXXXXXXXXX 1140 L ++ D + EL+E + I + +S E + + + Sbjct: 847 LEKKHADVVAELEEQHKEEVVKIGEEHREEVSKIEEEHKKEVSRIREEHKKEVNMLEKRH 906 Query: 1141 XLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKII-QLETLNTELTGH-DVVNQEQINQ 1198 + E EE +E S L++ SA + TEL+E + + + ++ + E G + ++E++++ Sbjct: 907 AAVMTELEEHKKEMSELEKNSADVVTELEEKHREELGKMGEQHIEEMGKIEEKHREEVSR 966 Query: 1199 L----KSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTE 1254 + K ++ +L ++ +++ + E + +++R ++ + ++ RE + K Sbjct: 967 IEEQHKEEVAELEKKHTDVVVMLEEQHKEEVNVLEKRHADVVVVLEEK--HRE-EVSKMG 1023 Query: 1255 HELRVQLSAFESKYEQLLDSVQSSTQEETNKIVT--MEQVTSLQNKLQDKEEHLRNLQEK 1312 + + +++ E LLD ++ + + E +++ E L L K E ++N K Sbjct: 1024 EQHKEEVAELEKNNASLLDVIEENHKSEVSRLKEEHKESTRELVETLSQKNEEIQNSNNK 1083 Query: 1313 YADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINE 1372 ++ N I+ ++ D + + +++ N+ +M+++S I + Sbjct: 1084 IEELTNVIK----DLNDSIMCYKKKISEDVEKRNEYNEEIQKLNKRLNEMKDKSDKEIIK 1139 Query: 1373 ENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLEL-KDSEIYQKTHEYTITLTQRN 1431 + ++KK + +K+L ++ E+ D+ +K E I +N Sbjct: 1140 KEDEIKKLNKKISNYKIFEIKENTYKNSKMLINENKEEIIVDNICKEKISESDIEGKGKN 1199 Query: 1432 DEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEEL 1491 + + L + E+ + ++ K ++ + + N E +KE + + K +E+L Sbjct: 1200 LK---MILSLKKKERSVFSVSDNKNENNELVDIVRNTYINKIEVYKKEIK-DNNKNMEDL 1255 Query: 1492 NVKITESVSLNKQVAELNKALEEE---VAKTNEMQTALENQEIEIVTLNDEITNLQNMVR 1548 KI + + + + L EE + K EM+ N+ EI+ LND+I L + Sbjct: 1256 KNKIIDLSNELANLKNVKNVLTEENDNLRKEMEMKQNKVNENDEILNLNDDIIKLTKEI- 1314 Query: 1549 ASSSKIQKHVSFASDTKQ 1566 S +K++ +D +Q Sbjct: 1315 --SEWKEKNIKLENDIEQ 1330 Score = 125 bits (301), Expect = 1e-26 Identities = 230/1234 (18%), Positives = 529/1234 (42%), Gaps = 101/1234 (8%) Query: 424 KEYVISE--KDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNE---- 477 KEY + + K+T K+ +LE++ +E I+ E +NE Sbjct: 20 KEYELEDQLKETLKSITALSIKVKEYENKIEELENELKLEKEKQINKEYEKE-LNEKCEF 78 Query: 478 IAKVQEQLKQ-ELNDEIKD--VNVKDLI-----EKLKSAEEQITQLNDEIDAANKNMIKV 529 I + E LK+ ELN IK+ +N K++I EKL E + + N E + N + + Sbjct: 79 IKREMELLKEKELNINIKENKINNKEIITLKKEEKLNDIENEYIEKNKEKEKLNYEITNI 138 Query: 530 KSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYD 589 K + ++Q+ +N K+ NK++V L L + + E E +L + D Sbjct: 139 KMSLDKLSCEIQEKKENLEKI---NKKVVEKENNLRELKEFMKEKNEIIESLNKTIDDKK 195 Query: 590 SG-RMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADIS 648 + +E++ +K +E L ++ E +K L +E ++ +K ++E+K Sbjct: 196 NAYEKLETNFEEKRKMIEMLDSKLIEKEKKFEIKKEKLEKENEVIMEKLKDIENKEEHFK 255 Query: 649 QLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGT-------IKDLEN 701 + E K ++LE +++ L + + A +E K++ + L + I +++N Sbjct: 256 NKEEKFKNKEEKFINLENELNKLKSDLSKNACQMEIYKMEIKDLSQSLVEKEREIFEIKN 315 Query: 702 DKEDIMNKLQNYIQE--NMDLTDKLEKMSAE----KISELLAKINHEEQ---SKIQTQFG 752 + +D +N ++N + N D D K S E KI E + K+ E++ ++I ++ Sbjct: 316 EYDDKINNMKNKLSNFNNDDNDDNTVKCSEEIINKKIEEAVNKLIKEKEMELNEIHKKYN 375 Query: 753 IDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKA 812 ++ + + ++ + E E +K K I + + ++ R +E ++ L + Sbjct: 376 LEIEKIKNEINEKEKELEQNKKKHNI-EINDLTKEIQIREKKIEDVKEEYKIELSKLDSE 434 Query: 813 YSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDM 872 + I+ +EL N + L + + ++ + +E L Q L + N+ L ++++ Sbjct: 435 KNNIKIENNELNNEVNSLNNEVNSLNNEVNSLNNEINSLNNDKQTLSKNNKLLNDLINNL 494 Query: 873 QQHYNALVEKANRTD----LAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDL 928 + N K N+ + E + ++E K + + ++K+ +DL Sbjct: 495 KNEINNSDNKMNKMKEDIIMLNEELEGKCVVIDEIEKKYKNEIFIFEKKL-KEKENYDDL 553 Query: 929 EIEFNT-QIESAIRDKKVLNEK--YEKNIE-YVTQLEAQLQEYKNNIENLNMNVEELNKM 984 E N + + ++++K+ + K YE I Y E + + Y+N + L + + Sbjct: 554 NDEINILRNDISVKEKEFIEMKEFYENKINLYNKNFEEKTKYYENELNILRLKYNNEQDL 613 Query: 985 NLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKD---EEIIALNQKIN--NAQVSY 1039 ++ + ++QK +T+ Y + Y + I ++ + + E I + +N A + + Sbjct: 614 IKQIDELNIQKLKTEEK-YLQLYDDNIKMFKSICAKINTTYSENIKGSDLVNFVEAYIKH 672 Query: 1040 MS---MVSDYESKLAQFTTKLENME-EEMQRVSKQLLDSKQHNEELQILVREQDDQIKEL 1095 ++ ES + + +LE EE+ R+ ++ H +E+ + E +++ + Sbjct: 673 RDESRFDANSESGIKEVVAELEEKHREEVSRIREE------HKKEVVRIGEEHKEEVVRI 726 Query: 1096 KETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERS 1155 E + I + + ++ + + ++++EE + +E S Sbjct: 727 GEEHKEEVVKIGEQHREELGE-----KEEEHKKEVAKIGEQHKEEMVRIREEHK--KEVS 779 Query: 1156 VLQEQSAKLNTELQECYTKIIQL--ETLNTELTGHDVVNQEQINQL----KSKLEQLNTE 1209 ++E+ K EL++ T ++ + E E+ ++++++++ K ++ ++ E Sbjct: 780 RIREEHKKEMAELEDGRTDVVAVLEEEHKKEVVRIGEEHKKEVSKIEEEHKKEVSRIREE 839 Query: 1210 NDNLLSTVAELRSSISSAVDQRGFE----IAELWKQHLAQREADFQKTEHELRVQLSAFE 1265 + +S + + + + + ++++ E I E ++ +++ E + +K +R + Sbjct: 840 HKKEMSELEKKHADVVAELEEQHKEEVVKIGEEHREEVSKIEEEHKKEVSRIREEHKKEV 899 Query: 1266 SKYEQLLDSVQSSTQEETNKIVTMEQVTS-LQNKLQDKE-EHLRNLQEKYADVINQIEIL 1323 + E+ +V + +E ++ +E+ ++ + +L++K E L + E++ + + +IE Sbjct: 900 NMLEKRHAAVMTELEEHKKEMSELEKNSADVVTELEEKHREELGKMGEQHIEEMGKIEEK 959 Query: 1324 RSE----IEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKK 1379 E IE++ + E + + + ++ + EE + + Sbjct: 960 HREEVSRIEEQHKEEVAELEKKHTDVVVMLEEQHKEEVNVLEKRHADVVVVLEEKHREEV 1019 Query: 1380 SSXXXXXXXXXXXXRVNDAEA-KVLELTHQLELK--DSEIYQKTHEYTITLTQRNDEFEN 1436 S N+A V+E H+ E+ E + T E TL+Q+N+E +N Sbjct: 1020 SKMGEQHKEEVAELEKNNASLLDVIEENHKSEVSRLKEEHKESTRELVETLSQKNEEIQN 1079 Query: 1437 VRQQLVEYEKRIEDLT-----YEKE-SELAILRLKMHENA----NHYETMQKESEIERVK 1486 ++ E I+DL Y+K+ SE R + +E M+ +S+ E +K Sbjct: 1080 SNNKIEELTNVIKDLNDSIMCYKKKISEDVEKRNEYNEEIQKLNKRLNEMKDKSDKEIIK 1139 Query: 1487 LIEELNVKITESVSLNK--QVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQ 1544 +E+ K+ + +S K ++ E + + N+ + ++N E ++ +D + Sbjct: 1140 KEDEIK-KLNKKISNYKIFEIKENTYKNSKMLINENKEEIIVDNICKEKISESDIEGKGK 1198 Query: 1545 NM-VRASSSKIQKHVSFASDTKQGRDEQLDNTMN 1577 N+ + S K ++ V SD K +E +D N Sbjct: 1199 NLKMILSLKKKERSVFSVSDNKNENNELVDIVRN 1232 Score = 115 bits (276), Expect = 1e-23 Identities = 287/1493 (19%), Positives = 630/1493 (42%), Gaps = 152/1493 (10%) Query: 90 ISESLANTLKQKEILMEKIKQYK-ELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLS 148 + + L TLK L K+K+Y+ ++ + + + + + Sbjct: 24 LEDQLKETLKSITALSIKVKEYENKIEELENELKLEKEKQINKEYEKELNEKCEFIKREM 83 Query: 149 NTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNK---ATTXXXXXXXXXXX 205 +KEK+ +++ + K+ E L +EK+N+ + KNK Sbjct: 84 ELLKEKELNINIKENKINNKEIITLKKEEKLNDIENEYIEKNKEKEKLNYEITNIKMSLD 143 Query: 206 XXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKD---IESKDVRISSLEEANKLLEA 262 ++ K+ + K+ + + E ++ K+ + + IES + I + A + LE Sbjct: 144 KLSCEIQEKKENLEKINKKVVEKENNLRELKEFMKEKNEIIESLNKTIDDKKNAYEKLE- 202 Query: 263 ARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMT 322 FE E K+ + L+ ++ E E+ +IE K N Sbjct: 203 TNFE---EKRKMIEMLDSKLIEKEKKFEIKKEKLEKENEVIMEKLKDIENKEE-HFKNKE 258 Query: 323 ELTK-KIELLEHLNCQIRQTNKELENKLATM---GTESKAVS-SPSKKGSPLISRKSG-R 376 E K K E +L ++ + +L M E K +S S +K + K+ Sbjct: 259 EKFKNKEEKFINLENELNKLKSDLSKNACQMEIYKMEIKDLSQSLVEKEREIFEIKNEYD 318 Query: 377 NTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISE----KD 432 + + MK+ S +++ N D K ++ I K + +++NK + +KE ++E + Sbjct: 319 DKINNMKNKLSNFNNDD-NDDNTVKCSEEIINK--KIEEAVNKLIKEKEMELNEIHKKYN 375 Query: 433 TXXXXXXXXXXGKDTLIAQLQLEHQQHMEG-PSLIHV-GTNTEDVNEIAKVQ-EQLKQEL 489 K+ + Q + +H + I + EDV E K++ +L E Sbjct: 376 LEIEKIKNEINEKEKELEQNKKKHNIEINDLTKEIQIREKKIEDVKEEYKIELSKLDSEK 435 Query: 490 ND---EIKDVN--VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKL---KLKQMQ 541 N+ E ++N V L ++ S ++ LN+EI++ N + + N+KL + ++ Sbjct: 436 NNIKIENNELNNEVNSLNNEVNSLNNEVNSLNNEINSLNNDKQTLSKNNKLLNDLINNLK 495 Query: 542 KTIDNF-SKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYK 600 I+N +K++ ++I+ L EEL + E+E++ N ++ + + ++ E + Y Sbjct: 496 NEINNSDNKMNKMKEDIIMLNEELEGKCVVIDEIEKKYKN-EIFIFE---KKLKEKENYD 551 Query: 601 KMIEMENLA--ETRLKAISLLESQKFDLVQELHILQQKYDE----VEDKLADISQLQSDQ 654 + + N+ + +K +E ++F ++++ + ++E E++L +I +L+ + Sbjct: 552 DLNDEINILRNDISVKEKEFIEMKEF-YENKINLYNKNFEEKTKYYENEL-NILRLKYNN 609 Query: 655 VCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDL--ENDK-EDIMNKLQ 711 IK + E I L +K L L +N+K+ K + I EN K D++N ++ Sbjct: 610 EQDLIKQID-ELNIQKLKTEEKYLQLYDDNIKMFK-SICAKINTTYSENIKGSDLVNFVE 667 Query: 712 NYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESEL 771 YI+ + + + S I E++A++ + + ++ ++I+E + + + Sbjct: 668 AYIKHRDE--SRFDANSESGIKEVVAELEEKHREEV-------SRIREE--HKKEVVRIG 716 Query: 772 SKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLM 831 ++K + R+ E E+ E+ ++LG +E +K ++ Q E + R + Sbjct: 717 EEHKEEVVRIGEE--HKEEVVKIGEQHREELGEKEEEHKKEVAKIGEQHKEEMVR--IRE 772 Query: 832 DHDRVVEKQLLEIEHENKELQKKN----QILLEENQNLQISLSDMQQHYNALVEKANRTD 887 +H + V + E + E EL+ +L EE++ + + + + + +E+ ++ + Sbjct: 773 EHKKEVSRIREEHKKEMAELEDGRTDVVAVLEEEHKKEVVRIGEEHKKEVSKIEEEHKKE 832 Query: 888 LAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRD-KKVL 946 ++ +++ ++ +LE + E L Q K+E+ + E ++ + KK + Sbjct: 833 VSRIRE-EHKKEMSELEKKHADVVAE---LEEQHKEEVVKIGEEHREEVSKIEEEHKKEV 888 Query: 947 NEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQ 1006 + E++ + V LE + +E + EL K + +++ + +K + + EQ Sbjct: 889 SRIREEHKKEVNMLEKRHAAVMTELEEHKKEMSELEKNSADVVTELEEKHREELGKMGEQ 948 Query: 1007 YINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQR 1066 +I E+ K +++K E +++ + + V++ E K LE Sbjct: 949 HIEEMGK----IEEKHRE------EVSRIEEQHKEEVAELEKKHTDVVVMLE-------- 990 Query: 1067 VSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDAN 1126 +QH EE+ +L + D + L+E + K E ++A+ Sbjct: 991 --------EQHKEEVNVLEKRHADVVVVLEE---KHREEVSKMGEQHKEEVAELEKNNAS 1039 Query: 1127 NVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELT 1186 +D LK +E +E +E L E ++ N E+Q KI +L + +L Sbjct: 1040 LLDVIEENHKSEVSRLK-EEHKESTRE---LVETLSQKNEEIQNSNNKIEELTNVIKDLN 1095 Query: 1187 GHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQR 1246 + +++I++ K + N E L + E++ + ++ EI +L K+ + Sbjct: 1096 DSIMCYKKKISEDVEKRNEYNEEIQKLNKRLNEMKDKSDKEIIKKEDEIKKLNKKISNYK 1155 Query: 1247 EADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHL 1306 + ++ ++ ++ E+K E ++D++ E++ I + + L+ KE + Sbjct: 1156 IFEIKENTYK-NSKMLINENKEEIIVDNICKEKISESD-IEGKGKNLKMILSLKKKERSV 1213 Query: 1307 RNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQS 1366 ++ + + ++I+R+ ++ + +++ N++ + ++ + Sbjct: 1214 FSVSDNKNENNELVDIVRNTYINKIEVY--------------KKEIKDNNKNMEDLKNK- 1258 Query: 1367 ILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTIT 1426 I++++ E A LK + + KV E L L D +I + T E + Sbjct: 1259 IIDLSNELANLKNVKNVLTEENDNLRKEMEMKQNKVNENDEILNLND-DIIKLTKEIS-E 1316 Query: 1427 LTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVK 1486 ++N + EN +Q + E +I KE L I K++E+ N ++ + EIE+ K Sbjct: 1317 WKEKNIKLENDIEQ-INKEYKI------KEENLMI---KINESINEVNNLKNQIEIEKKK 1366 Query: 1487 LIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDE 1539 E LN T +V+ NK +E + + ++ N+EIE T ND+ Sbjct: 1367 K-ENLN---TSNVN--------NKIVENNILENGNLKQNNSNKEIEDKTGNDD 1407 Score = 68.1 bits (159), Expect = 2e-09 Identities = 87/490 (17%), Positives = 210/490 (42%), Gaps = 42/490 (8%) Query: 1084 LVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLK 1143 ++ + DDQ++E +E+ E T++ ++ + V LK Sbjct: 4 IIYDDDDQVRETGHNFKEYELEDQLKE------TLKSITALSIKVKEYENKIEELENELK 57 Query: 1144 VQEEEEFIQE-RSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVN---QEQINQL 1199 +++E++ +E L E+ + E++ K + + ++ +++ +E++N + Sbjct: 58 LEKEKQINKEYEKELNEKCEFIKREMELLKEKELNINIKENKINNKEIITLKKEEKLNDI 117 Query: 1200 KSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRV 1259 +++ + N E + L + ++ S+ D+ EI E K++L + + E+ LR Sbjct: 118 ENEYIEKNKEKEKLNYEITNIKMSL----DKLSCEIQEK-KENLEKINKKVVEKENNLR- 171 Query: 1260 QLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQ 1319 +L F + ++++S+ + ++ N L+ ++K + + L K + + Sbjct: 172 ELKEFMKEKNEIIESLNKTIDDKKNAY------EKLETNFEEKRKMIEMLDSKLIEKEKK 225 Query: 1320 IEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKK 1379 EI + ++E E + + + +K +E+ +N+ E +LK Sbjct: 226 FEIKKEKLEKENEVIMEKLKDIENKEEH----FKNKEEKFKN-KEEKFINLENELNKLKS 280 Query: 1380 SSXXXXXXXXXXXXRVNDAEAKVLELTHQL-ELK---DSEIYQKTHEYTITLTQRNDEFE 1435 + D ++E ++ E+K D +I ++ + ND+ Sbjct: 281 DLSKNACQMEIYKMEIKDLSQSLVEKEREIFEIKNEYDDKINNMKNKLSNFNNDDNDDNT 340 Query: 1436 -NVRQQLV--EYEKRIEDLTYEKESELAILR----LKMHENANHYETMQKESEIERVKLI 1488 ++++ + E+ + L EKE EL + L++ + N +KE E + K Sbjct: 341 VKCSEEIINKKIEEAVNKLIKEKEMELNEIHKKYNLEIEKIKNEINEKEKELEQNKKKHN 400 Query: 1489 EELNVKITESVSLNKQVAELNKALEEEVAK--TNEMQTALENQEI--EIVTLNDEITNLQ 1544 E+N E K++ ++ + + E++K + + +EN E+ E+ +LN+E+ +L Sbjct: 401 IEINDLTKEIQIREKKIEDVKEEYKIELSKLDSEKNNIKIENNELNNEVNSLNNEVNSLN 460 Query: 1545 NMVRASSSKI 1554 N V + +++I Sbjct: 461 NEVNSLNNEI 470 >UniRef50_Q54NP8 Cluster: Kinesin 4; n=3; Dictyostelium discoideum|Rep: Kinesin 4 - Dictyostelium discoideum AX4 Length = 1922 Score = 132 bits (318), Expect = 1e-28 Identities = 267/1392 (19%), Positives = 564/1392 (40%), Gaps = 144/1392 (10%) Query: 244 ESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPS 303 E D+ LEE KL+E + L +++L ++ + + E Sbjct: 568 EDLDLIYEELEENKKLIEEYESTLELLNNQLDEKEIEHKELLIIIDQWEQECTNR--ENQ 625 Query: 304 CEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKEL---ENKLATMGTESKAVS 360 +E EI+++ I + + K +E + I Q N +L E++ + + V Sbjct: 626 NQELLEIDQQSKQSIQQLND--KLLETKQQSKQSIDQLNLQLIDIESESSKNKKSFENVL 683 Query: 361 SPSKKGSPLISRKSGRNTASKMKSPWS--QLSSETLNQDTDKKINKNEIAKLEMVIQSLN 418 +K L R + +++S L++ L +T + N + + IQSLN Sbjct: 684 GVFEKSYRLAERLEDKYFTKEIESKKQIETLANSYLQLETTYQQQLNINQQSQQKIQSLN 743 Query: 419 KDLVDKEYV-ISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNE 477 D+ + V + KD K +I +LE + + +LI + E N Sbjct: 744 NDIEQFKLVWVPLKDQVNGYFQENQMFKQYII---ELEEKYN----TLIDLQKEVEQ-NY 795 Query: 478 IAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKL 537 + L+Q+ ND+ + + + L + + +Q+ N ++ N++ + L Sbjct: 796 LTNT---LEQQRNDQYQ-IEINQLTTEYNNQIQQLESTNQKLQTQLYNLLANATQSTQTL 851 Query: 538 KQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESD 597 +Q +T S +EI LT E+ L + + + NL ++ + ++ Sbjct: 852 EQQLQT---------SKQEIDTLTNEIEQLKNQYDIIRVDNDNLSKESLELKQILLSKTQ 902 Query: 598 VYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCS 657 ++ + + + ++ I LES D Q + L+ ++D+ + I Q +Q+ S Sbjct: 903 QLEEQLSLAQQQKGNIEIIQQLESIIVDNQQSIDQLKIEFDQSQQDNQSIKQ-SYNQLES 961 Query: 658 EIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQEN 717 + E Q L K+ + +K L+ +I + KE I + +Q Sbjct: 962 TLTLAQSENQ--RLLTENKQFITSLNEIK----SLFNSI---QQQKETIQLEFNQRLQS- 1011 Query: 718 MDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSR 777 + +EK E+++ + Q I++ + QE++ +S L+ Y Sbjct: 1012 -------WSLDSEKYKEIISTLEQSNQKSIESYESKSLEFQEKE---NQFDSLLTNYNQL 1061 Query: 778 ICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVV 837 + + E R ++ +Q + + D L+ + +L + Sbjct: 1062 FSKYNDLATSNESNRLEFDQFKKDSNQSIQSLESLERSLKSENDNLLQQSNLLKSQLESI 1121 Query: 838 EKQ--------LLEIEHENKELQKKN-----------QILLEENQ------NLQISLSDM 872 EKQ LE+E + EL K + Q+L+ +Q L+ +SD Sbjct: 1122 EKQKQDQLIPIQLELESKKCELSKLSSQFSEQTKQVTQLLISVDQYKISTNKLESQISDR 1181 Query: 873 QQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEF 932 + N L KA + + E+ + QL L+ K T + +I KKE+E L +F Sbjct: 1182 NEEINNLKLKAIEINALKEENISLKDQLTKLKKAPKSQTDREKDMI---KKELEKLREKF 1238 Query: 933 N---TQIESAIRDKKVL---NEKYEKNIEYV----TQLEAQLQEYKNNIENLNMNVEELN 982 N +++ AI+DK+ + + E+ I+ + T E +L + K +L +V+ + Sbjct: 1239 NAIDAKLKQAIQDKQTIQSEKQSLEREIKDLKRSHTSTETELDKLKKT--HLAADVKSKD 1296 Query: 983 KMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSM 1042 + L + + K Q Q + ++++K N L++K EE++ LNQ + + Sbjct: 1297 FIALNKSVEILTKSQEQLKSTIIELESDLSKKNIELEKKQEELVTLNQDKLEKEKKTNQL 1356 Query: 1043 VSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELK-ETKLT 1101 SD+ S T KLEN E ++ +++ +++D K +E + E + IK+ + K + Sbjct: 1357 ESDHSSA----TIKLENYENQITQLTSEIIDLKSKFQEFK---SESESNIKQQEINLKES 1409 Query: 1102 FEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQS 1161 ++N T + +SD D + E + I+E LQE Sbjct: 1410 NDLNQQLTNDKF--ELTKQLSDLKVEFDKSKQLWST-----RSSESNDTIKE---LQESI 1459 Query: 1162 AKLNTELQECYTKIIQL-ETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAEL 1220 + E Q ++++L + +N + ++ +N Q QL L+ + + N+ ++ L Sbjct: 1460 ISKDKERQLTSEQLVKLTDQINLKTWEYNDLN-SQCQQLTKTLQNVKSSNEQQEQSIVSL 1518 Query: 1221 RSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQ 1280 S S+ + EI+++ + H + + + +++L S+ + L++ Q + Q Sbjct: 1519 ESQTSAKIKSLELEISQIQENHRLE-VLELNRCKNQL--------SEKQTLME--QDNIQ 1567 Query: 1281 EETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXX 1340 I + Q T +N++ E ++ +L+ + ++ ++IE + + E EK Sbjct: 1568 LNERIIQLLHQKTKHENEILSMESNIIDLENQTKELKSKIETAQQDFEIEKNYHTGLNET 1627 Query: 1341 XXXXXXXXXXDLRTENQSYKQM--QEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDA 1398 +L NQ+ +Q+ + + + + Q ++ ++ D Sbjct: 1628 NTTTIKTMNEELTRSNQTIQQLLFKISKLEQTSLQTQQQQELQQATISAQQQKQQQLADD 1687 Query: 1399 EAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESE 1458 + K +L +++L + E+ + T + + +T++ E+ EY I D KE E Sbjct: 1688 QEK-QQLYQKIKLIEKEL-ESTKQKNLYITEQFTLKES------EYLDTITDYVC-KEKE 1738 Query: 1459 LAILRLKMHENANHYETMQK-ESEIERVKLIEELNVKITESVSLNKQVAELNKALEEE-- 1515 + + +A + + +++ K ++ VK++ S +N+ + L++ Sbjct: 1739 FEKSKASLKTSATKIQALNDIIKKLQEEKPQQQPVVKVSSSQVVNQNGQPIKSILKKPKL 1798 Query: 1516 -VAKTNEMQTALENQEIEIVTLNDEITNLQ-NMVRASSS-----KIQKHVSFASDTKQGR 1568 + ++Q + +E+ + TLN +N + V ASS+ I K++ S+ Sbjct: 1799 VIIPREQLQQPPQFKELTLSTLNSNDSNCEPESVSASSTLTSLQSISKYIGKRSEQTTLE 1858 Query: 1569 DEQLDNTMNKEL 1580 + +T+N L Sbjct: 1859 HDLTSSTLNLPL 1870 Score = 122 bits (293), Expect = 1e-25 Identities = 228/1123 (20%), Positives = 467/1123 (41%), Gaps = 99/1123 (8%) Query: 473 EDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSN 532 E + +I + + L ++K ++ + E+L+ ++ I + ++ N + + + Sbjct: 545 ETIKKIKDLDDSLGISGQVKVKREDLDLIYEELEENKKLIEEYESTLELLNNQLDEKEIE 604 Query: 533 HKLKLKQMQKTIDNFSKVSDSNKEIVRLTEE----LHHLSQKVAELEEEK----GNLQLH 584 HK L + + + + N+E++ + ++ + L+ K+ E +++ L L Sbjct: 605 HKELLIIIDQWEQECTNRENQNQELLEIDQQSKQSIQQLNDKLLETKQQSKQSIDQLNLQ 664 Query: 585 LVDYDSGRMIESDVYKKMIE-MENLAETRLKAISLLESQKF----DLVQELHILQQKYDE 639 L+D +S ES KK E + + E + LE + F + +++ L Y + Sbjct: 665 LIDIES----ESSKNKKSFENVLGVFEKSYRLAERLEDKYFTKEIESKKQIETLANSYLQ 720 Query: 640 VEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDL 699 +E QL +Q S+ K L I+ L + + + I +L Sbjct: 721 LETTYQ--QQLNINQQ-SQQKIQSLNNDIEQFKLVWVPLKDQVNGYFQENQMFKQYIIEL 777 Query: 700 ENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQE 759 E +K + + LQ +++N LT+ LE+ ++ + ++ E ++IQ + K+Q Sbjct: 778 E-EKYNTLIDLQKEVEQNY-LTNTLEQQRNDQYQIEINQLTTEYNNQIQQLESTNQKLQT 835 Query: 760 RDLY---------IENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQ 810 + LY + +E +L K I L I ++++ + D L E + Sbjct: 836 Q-LYNLLANATQSTQTLEQQLQTSKQEIDTLTNEIEQLKNQYDIIRVDNDNLSKESLELK 894 Query: 811 KAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLS 870 + T Q +E ++ LA + + +QL I +N+ Q +Q+ +E +Q+ Q + S Sbjct: 895 QILLSKTQQLEEQLS-LAQQQKGNIEIIQQLESIIVDNQ--QSIDQLKIEFDQSQQDNQS 951 Query: 871 DMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEI 930 ++Q YN L + LA+SE+ + T+ + ++L I ++ QK E +++ Sbjct: 952 -IKQSYNQL---ESTLTLAQSENQRLLTENKQFITSLNEIKSLFNSIQQQK----ETIQL 1003 Query: 931 EFNTQIESAIRDKK-------VLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEEL-N 982 EFN +++S D + L + +K+IE + QE +N ++L N +L + Sbjct: 1004 EFNQRLQSWSLDSEKYKEIISTLEQSNQKSIESYESKSLEFQEKENQFDSLLTNYNQLFS 1063 Query: 983 KMN-LELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMS 1041 K N L ++ + + Q + Q I + L LK +++ ++ Q+ N + S Sbjct: 1064 KYNDLATSNESNRLEFDQFKKDSNQSIQSLESLERSLKSENDNLL---QQSNLLKSQLES 1120 Query: 1042 MVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLT 1101 + + +L +LE+ + E+ ++S Q S+Q + Q+L+ DQ K + KL Sbjct: 1121 IEKQKQDQLIPIQLELESKKCELSKLSSQF--SEQTKQVTQLLI--SVDQYK-ISTNKLE 1175 Query: 1102 FEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQS 1161 +++ E + ++ + + N + LK + + +E+ +++++ Sbjct: 1176 SQISDRNEE----INNLKLKAIEINALKEENISLKDQLTKLKKAPKSQTDREKDMIKKEL 1231 Query: 1162 AKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELR 1221 KL + K+ Q + + +I LK TE D L T Sbjct: 1232 EKLREKFNAIDAKLKQAIQDKQTIQSEKQSLEREIKDLKRSHTSTETELDKLKKT----- 1286 Query: 1222 SSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQE 1281 +++ V + F + L + + + T EL LS + E+ + + + Q+ Sbjct: 1287 -HLAADVKSKDFIALNKSVEILTKSQEQLKSTIIELESDLSKKNIELEKKQEELVTLNQD 1345 Query: 1282 ETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXX 1341 + K E+ T N+L+ E Y NQI L SEI D K F Sbjct: 1346 KLEK----EKKT---NQLESDHSSATIKLENYE---NQITQLTSEIIDLKSKFQEFKSES 1395 Query: 1342 XXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAK 1401 +L+ N +Q+ E QL R +++ Sbjct: 1396 ESNIKQQEINLKESNDLNQQLTNDKF----ELTKQLSDLKVEFDKSKQLWSTRSSESNDT 1451 Query: 1402 VLELTHQLELKDSEIYQKTHEYTITLTQRND----EFENVRQQLVEYEKRIEDL-TYEKE 1456 + EL + KD E Q T E + LT + + E+ ++ Q + K ++++ + ++ Sbjct: 1452 IKELQESIISKDKE-RQLTSEQLVKLTDQINLKTWEYNDLNSQCQQLTKTLQNVKSSNEQ 1510 Query: 1457 SELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEV 1516 E +I+ L+ +A K E+E ++ E +++ E Q++E +E++ Sbjct: 1511 QEQSIVSLESQTSAK-----IKSLELEISQIQENHRLEVLELNRCKNQLSEKQTLMEQDN 1565 Query: 1517 AKTNEMQTALENQ----EIEIVTLNDEITNLQNMVRASSSKIQ 1555 + NE L +Q E EI+++ I +L+N + SKI+ Sbjct: 1566 IQLNERIIQLLHQKTKHENEILSMESNIIDLENQTKELKSKIE 1608 Score = 120 bits (290), Expect = 3e-25 Identities = 260/1346 (19%), Positives = 548/1346 (40%), Gaps = 117/1346 (8%) Query: 317 EIANMTELTKKIE--LLEHLNCQIR--QTNKELENKLATMGTESKAVSSPSKKGSPLISR 372 ++A+ + KK E +LE N ++ + N L N ++T S K+ + I Sbjct: 351 QVADANTMLKKYESEILELQNQLVKSEEINSLLRNTISTQEISSNNFKLGMKRFNDAIIG 410 Query: 373 KSGRNTASKMKSPWSQLSSETLNQDT--DKKINKNEIAKLEMVIQSLNKDLVDKEYVISE 430 S N K K + L L +D KKI K+E K++ + S N E Sbjct: 411 GSLINENKKKKKRRNTLDPSYLLKDKIIKKKIRKSENQKIKKIKNSENNISSSSSNSSGE 470 Query: 431 KDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELN 490 +D E + T+ ED + + + + + Sbjct: 471 EDDDDKDDENNYSINQDDKDDSNYEDDDDEDEDDDEESDTDNEDDEDNDEDNDDDDDD-D 529 Query: 491 DEIKDVNVKDLIEKLKSAE-EQITQLNDEIDAANKNMIKVKSNHKL--KLKQMQKTIDNF 547 DE KD N+ +LIE L ++I L+D + + + +K + + +L++ +K I+ + Sbjct: 530 DEFKD-NL-NLIEPLDDETIKKIKDLDDSLGISGQVKVKREDLDLIYEELEENKKLIEEY 587 Query: 548 SKVSDS-NKEIVRLTEELHHLSQKVAELEEE-----KGNLQLHLVDYDSGRMIESDVYKK 601 + N ++ E L + + E+E N +L +D S + I+ + K Sbjct: 588 ESTLELLNNQLDEKEIEHKELLIIIDQWEQECTNRENQNQELLEIDQQSKQSIQQ-LNDK 646 Query: 602 MIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVE---DKLADISQLQSDQVCSE 658 ++E + ++ ++I L Q D+ E ++ ++ V +K +++ D+ + Sbjct: 647 LLETKQQSK---QSIDQLNLQLIDIESESSKNKKSFENVLGVFEKSYRLAERLEDKYFT- 702 Query: 659 IKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKED-------IMNKLQ 711 K + ++QI+ L+ S +L + +Q I+ L ND E + +++ Sbjct: 703 -KEIESKKQIETLANSYLQLETTYQQQLNINQQSQQKIQSLNNDIEQFKLVWVPLKDQVN 761 Query: 712 NYIQEN-------MDLTDKLEKMS--AEKISELLAKINHEEQSKIQTQFGIDAKIQERDL 762 Y QEN ++L +K + +++ + E+Q Q Q I+ E + Sbjct: 762 GYFQENQMFKQYIIELEEKYNTLIDLQKEVEQNYLTNTLEQQRNDQYQIEINQLTTEYNN 821 Query: 763 YIENIESELSKYKSRICRL----EESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTI 818 I+ +ES K ++++ L +S +E + + +++ D L + +++ + Y + Sbjct: 822 QIQQLESTNQKLQTQLYNLLANATQSTQTLEQQLQTSKQEIDTLTNEIEQLKNQYDIIRV 881 Query: 819 QEDEL----VNRLAVLMDHDRVVEKQLLEIEHE--NKELQKKNQILLEENQN----LQIS 868 D L + +L+ + +E+QL + + N E+ ++ + ++ +NQ L+I Sbjct: 882 DNDNLSKESLELKQILLSKTQQLEEQLSLAQQQKGNIEIIQQLESIIVDNQQSIDQLKIE 941 Query: 869 LSDMQQHYNALVEKANRTD----LAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKE 924 QQ ++ + N+ + LA+SE+ + T+ + ++L I ++ QK Sbjct: 942 FDQSQQDNQSIKQSYNQLESTLTLAQSENQRLLTENKQFITSLNEIKSLFNSIQQQK--- 998 Query: 925 IEDLEIEFNTQIESAIRDKK-------VLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMN 977 E +++EFN +++S D + L + +K+IE + QE +N ++L N Sbjct: 999 -ETIQLEFNQRLQSWSLDSEKYKEIISTLEQSNQKSIESYESKSLEFQEKENQFDSLLTN 1057 Query: 978 VEEL-NKMN-LELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNA 1035 +L +K N L ++ + + Q + Q I + L LK +++ ++ + + + Sbjct: 1058 YNQLFSKYNDLATSNESNRLEFDQFKKDSNQSIQSLESLERSLKSENDNLLQQSNLLKSQ 1117 Query: 1036 QVSYMSMVSDY--------ESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVRE 1087 S D ESK + + E+ ++V++ L+ Q+ L + Sbjct: 1118 LESIEKQKQDQLIPIQLELESKKCELSKLSSQFSEQTKQVTQLLISVDQYKISTNKLESQ 1177 Query: 1088 QDDQIKELKETKL-TFEMNIPKTEGMIISSTIE-----PMSDDANNVDXXXXXXXXXXXX 1141 D+ +E+ KL E+N K E + + + P S D Sbjct: 1178 ISDRNEEINNLKLKAIEINALKEENISLKDQLTKLKKAPKSQTDREKDMIKKELEKLREK 1237 Query: 1142 LKVQEEE--EFIQERSVLQEQSAKLNTELQEC---YTKI-IQLETLNTELTGHDVVNQEQ 1195 + + + IQ++ +Q + L E+++ +T +L+ L DV +++ Sbjct: 1238 FNAIDAKLKQAIQDKQTIQSEKQSLEREIKDLKRSHTSTETELDKLKKTHLAADVKSKDF 1297 Query: 1196 INQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEH 1255 I L +E L + L ST+ EL S +S + + EL L Q + + +K + Sbjct: 1298 I-ALNKSVEILTKSQEQLKSTIIELESDLSKKNIELEKKQEELVT--LNQDKLEKEKKTN 1354 Query: 1256 ELRVQLSAFESKYEQLLDSVQSSTQEETN-KIVTMEQVTSLQNKLQDKEEHLRNLQEKYA 1314 +L S+ K E + + T E + K E + ++ ++ +E +L+ + Sbjct: 1355 QLESDHSSATIKLENYENQITQLTSEIIDLKSKFQEFKSESESNIKQQEINLKESNDLNQ 1414 Query: 1315 DVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEEN 1374 + N L ++ D KV F N + K++QE SI++ ++E Sbjct: 1415 QLTNDKFELTKQLSDLKVEFDKSKQLWSTRSSES-------NDTIKELQE-SIISKDKER 1466 Query: 1375 AQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEF 1434 + ND ++ +LT L+ S Q+ +Q + + Sbjct: 1467 QLTSEQLVKLTDQINLKTWEYNDLNSQCQQLTKTLQNVKSSNEQQEQSIVSLESQTSAKI 1526 Query: 1435 ENVRQQLVEYEK--RIEDLTYEK-ESELAILRLKMHENANHYETMQKESEIERVKLIEEL 1491 +++ ++ + ++ R+E L + +++L+ + M ++ + + ++ ++ K E Sbjct: 1527 KSLELEISQIQENHRLEVLELNRCKNQLSEKQTLMEQD--NIQLNERIIQLLHQKTKHEN 1584 Query: 1492 NVKITES--VSLNKQVAELNKALE---EEVAKTNEMQTAL-ENQEIEIVTLNDEITNLQN 1545 + ES + L Q EL +E ++ T L E I T+N+E+T Sbjct: 1585 EILSMESNIIDLENQTKELKSKIETAQQDFEIEKNYHTGLNETNTTTIKTMNEELTRSNQ 1644 Query: 1546 MVRASSSKIQKHVSFASDTKQGRDEQ 1571 ++ KI K + T+Q ++ Q Sbjct: 1645 TIQQLLFKISKLEQTSLQTQQQQELQ 1670 Score = 120 bits (289), Expect = 3e-25 Identities = 222/1057 (21%), Positives = 453/1057 (42%), Gaps = 97/1057 (9%) Query: 587 DYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLAD 646 D D I V K +++ + E + L+E +++ EL Q E+E K Sbjct: 552 DLDDSLGISGQVKVKREDLDLIYEELEENKKLIE--EYESTLELLNNQLDEKEIEHKELL 609 Query: 647 ISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDI 706 I Q +Q C+ ++ + +E ++ SK+ + + + L K+Q +I L DI Sbjct: 610 IIIDQWEQECTNRENQN-QELLEIDQQSKQSIQQLNDKLLETKQQSKQSIDQLNLQLIDI 668 Query: 707 MNKLQNYIQENMDLTDKLEKMS--AEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYI 764 ++ + ++ EK AE++ + E +SK Q + ++ +Q Y Sbjct: 669 ESESSKNKKSFENVLGVFEKSYRLAERLEDKY--FTKEIESKKQIETLANSYLQLETTYQ 726 Query: 765 ENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELV 824 + + + + +I L I E + DQ+ Y QE Q + +Y I+ +E Sbjct: 727 QQLNIN-QQSQQKIQSLNNDI---EQFKLVWVPLKDQVNGYFQENQM-FKQYIIELEEKY 781 Query: 825 NRLAVLMDHDRVVEKQLLE--IEHE-NKELQKK-NQILLEENQNLQISLSDMQ----QHY 876 N L+D + VE+ L +E + N + Q + NQ+ E N +Q S Q Q Y Sbjct: 782 N---TLIDLQKEVEQNYLTNTLEQQRNDQYQIEINQLTTEYNNQIQQLESTNQKLQTQLY 838 Query: 877 NALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKK-EIEDLEI-EFNT 934 N L T E + + ++ L + ++++ +++ + V E LE+ + Sbjct: 839 NLLANATQSTQTLEQQLQTSKQEIDTLTNEIEQLKNQYDIIRVDNDNLSKESLELKQILL 898 Query: 935 QIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQ 994 + ++ L ++ + NIE + QLE+ + + + +I+ L + ++ + N + + Q Sbjct: 899 SKTQQLEEQLSLAQQQKGNIEIIQQLESIIVDNQQSIDQLKIEFDQSQQDNQSIKQSYNQ 958 Query: 995 KQQT----QSPDY-----TEQYINEINKLNALLK--QKDEEIIAL--NQKINNAQVS--- 1038 + T QS + +Q+I +N++ +L Q+ +E I L NQ++ + + Sbjct: 959 LESTLTLAQSENQRLLTENKQFITSLNEIKSLFNSIQQQKETIQLEFNQRLQSWSLDSEK 1018 Query: 1039 YMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKET 1098 Y ++S E + E+ E Q Q DS N L + +D + Sbjct: 1019 YKEIISTLEQSNQKSIESYESKSLEFQEKENQF-DSLLTNYNQ--LFSKYNDLATSNESN 1075 Query: 1099 KLTFEMNIPKTEGMI--ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSV 1156 +L F+ + I + S + + +N+ ++ Q++++ I + Sbjct: 1076 RLEFDQFKKDSNQSIQSLESLERSLKSENDNLLQQSNLLKSQLESIEKQKQDQLIPIQLE 1135 Query: 1157 LQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLST 1216 L+ + +L+ + + Q+ L + + + N+L+S++ N E +NL Sbjct: 1136 LESKKCELSKLSSQFSEQTKQVTQLLISVDQYKI----STNKLESQISDRNEEINNLKLK 1191 Query: 1217 VAELRSSISSAVDQRGFEIAELWKQHLAQ--READFQKTEHE-LRVQLSAFESKYEQLLD 1273 E+ + + + ++ +L K +Q RE D K E E LR + +A ++K +Q + Sbjct: 1192 AIEINALKEENISLKD-QLTKLKKAPKSQTDREKDMIKKELEKLREKFNAIDAKLKQAIQ 1250 Query: 1274 ---SVQSSTQEETNKIVTMEQV-TSLQNKLQD-KEEHLR-NLQEKYADVINQ-IEILRSE 1326 ++QS Q +I +++ TS + +L K+ HL +++ K +N+ +EIL Sbjct: 1251 DKQTIQSEKQSLEREIKDLKRSHTSTETELDKLKKTHLAADVKSKDFIALNKSVEILTKS 1310 Query: 1327 IEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXX 1386 E K DL +N ++ QE+ ++ +N++ + +K + Sbjct: 1311 QEQLK-----------STIIELESDLSKKNIELEKKQEE-LVTLNQDKLEKEKKTNQLES 1358 Query: 1387 XXXXXXXRVNDAEAKVLELTHQL-ELKD------SEIYQKTHEYTITLTQRNDEFENVRQ 1439 ++ + E ++ +LT ++ +LK SE + I L + ND + + Sbjct: 1359 DHSSATIKLENYENQITQLTSEIIDLKSKFQEFKSESESNIKQQEINLKESNDLNQQLTN 1418 Query: 1440 QLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQ-------KESEI---ERVKLIE 1489 E K++ DL E + + + E+ + + +Q KE ++ + VKL + Sbjct: 1419 DKFELTKQLSDLKVEFDKSKQLWSTRSSESNDTIKELQESIISKDKERQLTSEQLVKLTD 1478 Query: 1490 ELNVKITESVSLNKQVAELNKALEEEVAKTNEMQ----TALENQ-EIEIVTLNDEITNLQ 1544 ++N+K E LN Q +L K L + V +NE Q +LE+Q +I +L EI+ +Q Sbjct: 1479 QINLKTWEYNDLNSQCQQLTKTL-QNVKSSNEQQEQSIVSLESQTSAKIKSLELEISQIQ 1537 Query: 1545 NMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELL 1581 R ++ + + S+ KQ EQ + +N+ ++ Sbjct: 1538 ENHRLEVLELNRCKNQLSE-KQTLMEQDNIQLNERII 1573 Score = 90.2 bits (214), Expect = 4e-16 Identities = 227/1139 (19%), Positives = 465/1139 (40%), Gaps = 92/1139 (8%) Query: 477 EIAKVQEQLKQELN-DEIKDVN--VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVK--- 530 + AK +++K +++ D N +K ++ + Q+ + ++EI++ +N I + Sbjct: 335 QFAKRAKRVKTNYKINQVADANTMLKKYESEILELQNQLVK-SEEINSLLRNTISTQEIS 393 Query: 531 -SNHKLKLKQMQKTIDNFSKVSDSNKEIVRLT--EELHHLSQKVAELEEEKGNLQLHLVD 587 +N KL +K+ I S ++++ K+ R + + L K+ + + K Q Sbjct: 394 SNNFKLGMKRFNDAIIGGSLINENKKKKKRRNTLDPSYLLKDKIIKKKIRKSENQKIKKI 453 Query: 588 YDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKL--A 645 +S I S E ++ + S+ + K D E + + D+ E Sbjct: 454 KNSENNISSSSSNSSGEEDDDDKDDENNYSINQDDKDDSNYEDDDDEDEDDDEESDTDNE 513 Query: 646 DISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKED 705 D D + ++ ++ + E I++L D + G +K D + Sbjct: 514 DDEDNDEDNDDDDDDDDEFKDNLNLIEPLDDETIKKIKDLD-DSLGISGQVKVKREDLDL 572 Query: 706 IMNKLQNYIQENMDLTDKLEKMSAEKISELLAK-INHEEQSKIQTQFGIDAKIQERDLYI 764 I +L+ EN L ++ E ++L K I H+E I Q+ + +E Sbjct: 573 IYEELE----ENKKLIEEYESTLELLNNQLDEKEIEHKELLIIIDQWEQECTNRENQNQ- 627 Query: 765 ENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELV 824 E +E + + K I +L + + +E ++ S ++ DQL L + + SE + + Sbjct: 628 ELLEID-QQSKQSIQQLNDKL--LETKQQS-KQSIDQLNLQLIDIE---SESSKNKKSFE 680 Query: 825 NRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKAN 884 N L V R+ E+ LE ++ KE++ K QI N LQ+ + QQ N + Sbjct: 681 NVLGVFEKSYRLAER--LEDKYFTKEIESKKQIETLANSYLQLETT-YQQQLNINQQSQQ 737 Query: 885 RTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIE--SAIRD 942 + ++ +++ L+ + E+Q K+ I +LE ++NT I+ + Sbjct: 738 KIQSLNNDIEQFKLVWVPLKDQVNGYFQENQMF----KQYIIELEEKYNTLIDLQKEVEQ 793 Query: 943 KKVLNE-KYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQT--Q 999 + N + ++N +Y ++ EY N I+ L ++L L+ Q QT Q Sbjct: 794 NYLTNTLEQQRNDQYQIEINQLTTEYNNQIQQLESTNQKLQTQLYNLLANATQSTQTLEQ 853 Query: 1000 SPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSY----MSMVSDYESKLAQFTT 1055 ++Q I+ + LK + + I N ++ + +S E +L+ Sbjct: 854 QLQTSKQEIDTLTNEIEQLKNQYDIIRVDNDNLSKESLELKQILLSKTQQLEEQLSLAQQ 913 Query: 1056 KLENMEEEMQRVSKQLLDSKQHNEELQILV--REQDDQIKELKETKLTFEMNIPKTEGMI 1113 + N+E +Q++ ++D++Q ++L+I +QD+Q + +L + + ++E Sbjct: 914 QKGNIEI-IQQLESIIVDNQQSIDQLKIEFDQSQQDNQSIKQSYNQLESTLTLAQSENQR 972 Query: 1114 ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYT 1173 + + + N + +Q+++E IQ + QS L++E Y Sbjct: 973 LLTENKQFITSLNEIKSLFNS---------IQQQKETIQLEFNQRLQSWSLDSEK---YK 1020 Query: 1174 KIIQLETLNTELTGHDVVNQEQINQLKSK-LEQLNTEN--DNLLSTVAELRSSISSAVDQ 1230 +II TL NQ+ I +SK LE EN D+LL+ +L S + Sbjct: 1021 EIIS--TLEQS-------NQKSIESYESKSLEFQEKENQFDSLLTNYNQLFSKYNDLATS 1071 Query: 1231 RGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLD-SVQSSTQEETNKIVTM 1289 E + Q + D ++ L + +S+ + LL S +Q E+ + Sbjct: 1072 N-----ESNRLEFDQFKKDSNQSIQSLESLERSLKSENDNLLQQSNLLKSQLESIEKQKQ 1126 Query: 1290 EQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXX 1349 +Q+ +Q +L+ K+ L L ++++ Q+ L ++ K++ Sbjct: 1127 DQLIPIQLELESKKCELSKLSSQFSEQTKQVTQLLISVDQYKISTNKLESQISD------ 1180 Query: 1350 XDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLE-LTHQ 1408 R E + +++ I + EEN LK R D K LE L + Sbjct: 1181 ---RNEEINNLKLKAIEINALKEENISLKDQLTKLKKAPKSQTDREKDMIKKELEKLREK 1237 Query: 1409 LELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAI-LRLKMH 1467 D+++ Q + +++ ++ + +L K++ LA ++ K Sbjct: 1238 FNAIDAKLKQAIQDKQTIQSEKQSLEREIKDLKRSHTSTETELDKLKKTHLAADVKSKDF 1297 Query: 1468 ENANH-YETMQKESEIERVKLIE---ELNVKITESVSLNKQVAELNKALEEEVAKTNEMQ 1523 N E + K E + +IE +L+ K E +++ LN+ E+ KTN+++ Sbjct: 1298 IALNKSVEILTKSQEQLKSTIIELESDLSKKNIELEKKQEELVTLNQDKLEKEKKTNQLE 1357 Query: 1524 TALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQL--DNTMNKEL 1580 + + I++ ++IT L + + SK Q+ S + + ++ L N +N++L Sbjct: 1358 SDHSSATIKLENYENQITQLTSEIIDLKSKFQEFKSESESNIKQQEINLKESNDLNQQL 1416 >UniRef50_A2DLG1 Cluster: Viral A-type inclusion protein, putative; n=1; Trichomonas vaginalis G3|Rep: Viral A-type inclusion protein, putative - Trichomonas vaginalis G3 Length = 883 Score = 132 bits (318), Expect = 1e-28 Identities = 200/965 (20%), Positives = 438/965 (45%), Gaps = 113/965 (11%) Query: 608 LAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQ 667 +A+ +++S + S L ++QQ+ DE+ ++L I++L S S+I++ +E Q Sbjct: 1 MAQISAESVSKIRSADELKKTALKLIQQR-DEINEQLT-IAKLSSSAFESQIQAYKMELQ 58 Query: 668 IDALSASKKELALVIENLK--LDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLE 725 S A + E +K ++ E K + D + + +L N I T KLE Sbjct: 59 ASQQKESSLN-AFIDEMMKEKMNFETKLNEQKQIMTDNNEKIKQLNNEIS-----TLKLE 112 Query: 726 KMSAE-KISEL-----LAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRIC 779 S E K+++L LA N + ++ Q I + +E++ IE + E + + +I Sbjct: 113 NSSYEQKVNDLMQIINLAPSNPAQDQILELQRTIKQQNKEQNYLIEAFDIEKKELEEQIK 172 Query: 780 RLEESI--AVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRL-AVLMDHDRV 836 +L+ + + ++ + + + L + +Q+ + + + L+N ++++ Sbjct: 173 KLQSNSNNSEIDSLLLAFQEEKTSLEAQIQDLKAQLANN--DTETLINTFHKEKLEYEEK 230 Query: 837 VEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKY 896 V K L++ + KEL+ K+ EE +L ++S+ + + L ++ + E E+ K Sbjct: 231 VNKLLVDNDKLQKELKNKD----EEQTSLLQAISEDKDKLSKLFDETQKQLNEEKENLKK 286 Query: 897 QTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKK-VLNEKYEKNIE 955 Q +L L L+ + + I K I+ ++ + +++E ++D++ ++ K E ++ Sbjct: 287 QLKL--LNEQLENEKLQAKESIKAKDLVIQVIDSQ-RSELEQKLKDQEDIIKIKSENEVK 343 Query: 956 YVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLN 1015 L ++Q N+I+ + N + +L ++ + QQ + Y Q + Sbjct: 344 ----LSDEIQRLNNSIKEMQNN----SNSSLSDLNSQISSQQQKLNQYEAQDVQS----Q 391 Query: 1016 ALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSK 1075 A +K EI L QK N Q +++S+ + KLA+ +++ +++++++ + + Sbjct: 392 ATIKSLQTEIDVLKQKETNLQ----NLISEQDEKLAKQDQAIKDSQDKIKQLEEAAQNHS 447 Query: 1076 QHNEE-----LQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDX 1130 + +E +Q++ +E DD + E + N K I ++ +S++ NN Sbjct: 448 EEEKEKQFEIIQMITKENDDLKAQNSEY---VKQNQEKDRQ--IEELVQSLSNENNN--- 499 Query: 1131 XXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDV 1190 K +EE E + S L ++ +LNT++QE ++ QL TE + Sbjct: 500 ----NADIQKLYKEKEETELLI--SQLGDEITQLNTKIQEKVDEVNQL----TET----I 545 Query: 1191 VNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADF 1250 +++E++ + + +N +L + +AEL ++IS + + ++ L ++ + Sbjct: 546 LDKEEV------INAVTKDNSDLNNKIAELNNAISEMTKEITEKEEKI--NELNRKIEEL 597 Query: 1251 QKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQ 1310 E +++ F SK +L +S+ E N T + L N++++K+E + L Sbjct: 598 NNVIKEKEEEINRFSSKISELNESINEKINEINN---TNTAINELNNQIKEKDEKINELN 654 Query: 1311 EKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNI 1370 + + N+I+ L +E+ + + R + ++ ++ I I Sbjct: 655 NQNQEKQNKIDEL-NELNN-------TVQQNETKFGELNKENREKENRINELNKE-IERI 705 Query: 1371 NEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQR 1430 N +++ K+ + + + EL ++ K++EI QK ++ Sbjct: 706 NNSSSEKDKTIANLNESLLEKDNEITKKDELIKELQESVQTKETEINQKNE----LISSN 761 Query: 1431 NDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQ-KESEIERVKLIE 1489 N + + + QQ+ E +I D KE+ L + K+H ET+Q KE+EI + E Sbjct: 762 NTKIDELNQQINELNAQISD----KENSLKEITDKVHTLE---ETVQNKETEINQKN--E 812 Query: 1490 ELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRA 1549 EL+ + T+ LN+ +++ + E+ + NE + + N +IE LN +I+N +N ++ Sbjct: 813 ELSERETKINELNEIISQK----DSEIQQKNE-EISSNNSKIE--ELNQQISNKENSLQE 865 Query: 1550 SSSKI 1554 + K+ Sbjct: 866 LTDKV 870 Score = 132 bits (318), Expect = 1e-28 Identities = 196/894 (21%), Positives = 405/894 (45%), Gaps = 98/894 (10%) Query: 471 NTEDVNEIAKVQEQLKQELN--DEIKDVNVKDLIEKLKSA--EEQITQLNDEIDAANKNM 526 + E V++I E K L + ++N + I KL S+ E QI E+ A+ + Sbjct: 5 SAESVSKIRSADELKKTALKLIQQRDEINEQLTIAKLSSSAFESQIQAYKMELQASQQK- 63 Query: 527 IKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLV 586 +S+ + +M K NF + K+I +T+ ++K+ +L E L+L Sbjct: 64 ---ESSLNAFIDEMMKEKMNFETKLNEQKQI--MTDN----NEKIKQLNNEISTLKLENS 114 Query: 587 DYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQ--ELHILQQKYDEVEDKL 644 Y+ ++++ NLA + +LE Q+ Q E + L + +D + +L Sbjct: 115 SYEQK-------VNDLMQIINLAPSNPAQDQILELQRTIKQQNKEQNYLIEAFDIEKKEL 167 Query: 645 AD-ISQLQSDQVCSEIKSVHL--EEQIDALSASKKELALVIENLKLDKEQLYGTIKDLEN 701 + I +LQS+ SEI S+ L +E+ +L A ++L + N D E L T + Sbjct: 168 EEQIKKLQSNSNNSEIDSLLLAFQEEKTSLEAQIQDLKAQLANN--DTETLINTFHKEKL 225 Query: 702 DKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERD 761 + E+ +NKL + +N L +L+ E+ S LL I+ E++ K+ F Sbjct: 226 EYEEKVNKL---LVDNDKLQKELKNKDEEQTS-LLQAIS-EDKDKLSKLF---------- 270 Query: 762 LYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQED 821 + + +L++ K L++ + ++ ++ LE + Q ++ K Q Sbjct: 271 ---DETQKQLNEEKEN---LKKQLKLLNEQ---LENEKLQAKESIKAKDLVIQVIDSQRS 321 Query: 822 ELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVE 881 EL +L D ++ + +++ + E+Q+ N + E N SLSD+ ++ + Sbjct: 322 ELEQKLKDQEDIIKIKSENEVKL---SDEIQRLNNSIKEMQNNSNSSLSDLNSQISSQQQ 378 Query: 882 KANRTDL--AESEST--KYQTQ---LRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNT 934 K N+ + +S++T QT+ L+ E+NL+ + E + ++ + I+D + + Sbjct: 379 KLNQYEAQDVQSQATIKSLQTEIDVLKQKETNLQNLISEQDEKLAKQDQAIKDSQDKIKQ 438 Query: 935 QIESAIRDKKVLNEKYEKNIEYVTQ----LEAQLQEYKNNIENLNMNVEEL-------NK 983 E+A + EK + I+ +T+ L+AQ EY + + +EEL N Sbjct: 439 LEEAAQNHSEEEKEKQFEIIQMITKENDDLKAQNSEYVKQNQEKDRQIEELVQSLSNENN 498 Query: 984 MNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMV 1043 N ++ + +K++T+ Q +EI +LN +++K +E+ L + I + + ++ Sbjct: 499 NNADIQKLYKEKEETEL--LISQLGDEITQLNTKIQEKVDEVNQLTETILDKEEVINAVT 556 Query: 1044 SDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFE 1103 D S L +L N EM +K++ + ++ EL + E ++ IKE +E F Sbjct: 557 KD-NSDLNNKIAELNNAISEM---TKEITEKEEKINELNRKIEELNNVIKEKEEEINRFS 612 Query: 1104 MNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAK 1163 I + ++ +I ++ NN + +++E++E I E + ++ Sbjct: 613 SKISE-----LNESINEKINEINNTNTAINELNN-----QIKEKDEKINELNNQNQEKQN 662 Query: 1164 LNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSS 1223 EL E + Q ET EL + + +IN+L ++E++N + T+A L S Sbjct: 663 KIDELNELNNTVQQNETKFGELNKENREKENRINELNKEIERINNSSSEKDKTIANLNES 722 Query: 1224 I---SSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLD-SVQSST 1279 + + + ++ I EL ++ + +E + + + + + +Q+ + + Q S Sbjct: 723 LLEKDNEITKKDELIKEL-QESVQTKETEINQKNELISSNNTKIDELNQQINELNAQISD 781 Query: 1280 QEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYAD---VINQIEILRSEIEDE 1330 +E + K +T ++V +L+ +Q+KE + E+ ++ IN++ + S+ + E Sbjct: 782 KENSLKEIT-DKVHTLEETVQNKETEINQKNEELSERETKINELNEIISQKDSE 834 Score = 130 bits (315), Expect = 2e-28 Identities = 167/817 (20%), Positives = 348/817 (42%), Gaps = 55/817 (6%) Query: 445 KDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEK 504 K+ + + +L Q+ + + + +++ + +Q++ND ++ +N + Sbjct: 76 KEKMNFETKLNEQKQIMTDNNEKIKQLNNEISTLKLENSSYEQKVNDLMQIIN----LAP 131 Query: 505 LKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEEL 564 A++QI +L I NK + ++ K++++ I S+ N EI L L Sbjct: 132 SNPAQDQILELQRTIKQQNKEQNYLIEAFDIEKKELEEQIKKLQSNSN-NSEIDSL---L 187 Query: 565 HHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKF 624 ++ LE + +L+ L + D+ +I + +K+ +E E L L+ + Sbjct: 188 LAFQEEKTSLEAQIQDLKAQLANNDTETLINT-FHKEKLEYEEKVNKLLVDNDKLQKELK 246 Query: 625 DLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVH-----LEEQIDALSASKKELA 679 + +E L Q E +DKL+ + Q+ E +++ L EQ++ KE Sbjct: 247 NKDEEQTSLLQAISEDKDKLSKLFDETQKQLNEEKENLKKQLKLLNEQLENEKLQAKESI 306 Query: 680 ----LVIENLKLDKEQLYGTIKDLEN------DKE----DIMNKLQNYIQENMDLTDKLE 725 LVI+ + + +L +KD E+ + E D + +L N I+E + ++ Sbjct: 307 KAKDLVIQVIDSQRSELEQKLKDQEDIIKIKSENEVKLSDEIQRLNNSIKEMQNNSNSSL 366 Query: 726 KMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIE---NIESELSKYKSRICRLE 782 +IS K+N E +Q+Q I + E D+ + N+++ +S+ ++ + + Sbjct: 367 SDLNSQISSQQQKLNQYEAQDVQSQATIKSLQTEIDVLKQKETNLQNLISEQDEKLAKQD 426 Query: 783 ESIAVMEDRRYSLERKADQLGSYLQEKQ-KAYSEYTIQEDELVNRLAVLM----DHDRVV 837 ++I +D+ LE A +EKQ + T + D+L + + + + DR + Sbjct: 427 QAIKDSQDKIKQLEEAAQNHSEEEKEKQFEIIQMITKENDDLKAQNSEYVKQNQEKDRQI 486 Query: 838 EKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQ 897 E+ + + +EN Q L +E + ++ +S + L K E + Sbjct: 487 EELVQSLSNENNN-NADIQKLYKEKEETELLISQLGDEITQLNTKIQEK---VDEVNQLT 542 Query: 898 TQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYV 957 + D E + +T ++ L K E+ + E +I LN K E+ + Sbjct: 543 ETILDKEEVINAVTKDNSDLN-NKIAELNNAISEMTKEITEKEEKINELNRKIEELNNVI 601 Query: 958 TQLEAQLQEYKNNIENLNMNV-EELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNA 1016 + E ++ + + I LN ++ E++N++N + Q + D + INE+N N Sbjct: 602 KEKEEEINRFSSKISELNESINEKINEINNTNTAINELNNQIKEKD---EKINELNNQNQ 658 Query: 1017 LLKQKDEEIIALNQKINNAQVSYMSMVSDY---ESKLAQFTTKLENMEEEMQRVSKQLLD 1073 + K +E+ LN + + + + + E+++ + ++E + K + + Sbjct: 659 EKQNKIDELNELNNTVQQNETKFGELNKENREKENRINELNKEIERINNSSSEKDKTIAN 718 Query: 1074 SKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISST--IEPMSDDANNVDXX 1131 + E + ++D+ IKEL+E+ T E I + +I S+ I+ ++ N ++ Sbjct: 719 LNESLLEKDNEITKKDELIKELQESVQTKETEINQKNELISSNNTKIDELNQQINELNAQ 778 Query: 1132 XXXXXXXXXXL--KVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHD 1189 + KV EE +Q + Q N EL E TKI +L + ++ Sbjct: 779 ISDKENSLKEITDKVHTLEETVQNKETEINQK---NEELSERETKINELNEIISQKDSEI 835 Query: 1190 VVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISS 1226 E+I+ SK+E+LN + N +++ EL + S Sbjct: 836 QQKNEEISSNNSKIEELNQQISNKENSLQELTDKVHS 872 Score = 126 bits (305), Expect = 4e-27 Identities = 177/824 (21%), Positives = 374/824 (45%), Gaps = 82/824 (9%) Query: 300 IEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKL-ATMGTESKA 358 I+ +EK E K + + MT+ +KI+ L + ++ N E K+ M + A Sbjct: 71 IDEMMKEKMNFETKLNEQKQIMTDNNEKIKQLNNEISTLKLENSSYEQKVNDLMQIINLA 130 Query: 359 VSSPSKKGSPLISRKSGRNT-------------ASKMKSPWSQLSSETLNQDTDKKI--N 403 S+P++ + R + +++ +L S + N + D + Sbjct: 131 PSNPAQDQILELQRTIKQQNKEQNYLIEAFDIEKKELEEQIKKLQSNSNNSEIDSLLLAF 190 Query: 404 KNEIAKLEMVIQSLNKDLV--DKEYVIS--EKDTXXXXXXXXXXGKDTLIAQLQLEHQQH 459 + E LE IQ L L D E +I+ K+ D Q +L+++ Sbjct: 191 QEEKTSLEAQIQDLKAQLANNDTETLINTFHKEKLEYEEKVNKLLVDNDKLQKELKNKDE 250 Query: 460 MEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKL-KSAEEQITQLNDE 518 E SL+ +ED ++++K+ ++ +++LN+E + N+K ++ L + E + Q + Sbjct: 251 -EQTSLLQ--AISEDKDKLSKLFDETQKQLNEEKE--NLKKQLKLLNEQLENEKLQAKES 305 Query: 519 IDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEK 578 I A + +I+V + + +L+Q K ++ K+ N+ V+L++E+ L+ + E++ Sbjct: 306 IKAKDL-VIQVIDSQRSELEQKLKDQEDIIKIKSENE--VKLSDEIQRLNNSIKEMQ--- 359 Query: 579 GNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYD 638 N L D +S I S +K+ + E I L+++ L Q+ LQ Sbjct: 360 NNSNSSLSDLNS--QISSQ-QQKLNQYEAQDVQSQATIKSLQTEIDVLKQKETNLQNLIS 416 Query: 639 EVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVI--------ENLKLDKE 690 E ++KLA Q D S+ K LEE S +KE I ++LK Sbjct: 417 EQDEKLAKQDQAIKD---SQDKIKQLEEAAQNHSEEEKEKQFEIIQMITKENDDLKAQNS 473 Query: 691 QLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEK---ISEL---LAKINHEEQ 744 + ++ + E+++ L N N D+ KL K E IS+L + ++N + Q Sbjct: 474 EYVKQNQEKDRQIEELVQSLSNENNNNADI-QKLYKEKEETELLISQLGDEITQLNTKIQ 532 Query: 745 SKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVM-------EDRRYSLER 797 K+ + I +++ I + + S ++I L +I+ M E++ L R Sbjct: 533 EKVDEVNQLTETILDKEEVINAVTKDNSDLNNKIAELNNAISEMTKEITEKEEKINELNR 592 Query: 798 KADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQI 857 K ++L + ++EK++ + ++ + EL + ++ + E+ ++ KE +K Sbjct: 593 KIEELNNVIKEKEEEINRFSSKISELNESINEKINEINNTNTAINELNNQIKEKDEKINE 652 Query: 858 LLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRI----THE 913 L +NQ Q + ++ + N + + + E+ + + ++ +L ++RI + + Sbjct: 653 LNNQNQEKQNKIDELNELNNTVQQNETKFGELNKENREKENRINELNKEIERINNSSSEK 712 Query: 914 HQTL------IVQKKKEIEDLEIEFNTQIESAIRDKKV-LNEKYE---KNIEYVTQLEAQ 963 +T+ +++K EI + E +++ +++ K+ +N+K E N + +L Q Sbjct: 713 DKTIANLNESLLEKDNEITKKD-ELIKELQESVQTKETEINQKNELISSNNTKIDELNQQ 771 Query: 964 LQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYI---NEINKLNALLKQ 1020 + E I + +++E+ + +++ VQ ++T+ E+ +IN+LN ++ Q Sbjct: 772 INELNAQISDKENSLKEITD-KVHTLEETVQNKETEINQKNEELSERETKINELNEIISQ 830 Query: 1021 KDEEIIALNQKI--NNAQVSYMS-MVSDYESKLAQFTTKLENME 1061 KD EI N++I NN+++ ++ +S+ E+ L + T K+ ++E Sbjct: 831 KDSEIQQKNEEISSNNSKIEELNQQISNKENSLQELTDKVHSLE 874 Score = 111 bits (266), Expect = 2e-22 Identities = 180/914 (19%), Positives = 378/914 (41%), Gaps = 72/914 (7%) Query: 696 IKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDA 755 I+ + K+ + +Q + N LT + K+S+ + E Q+ Q + ++A Sbjct: 12 IRSADELKKTALKLIQQRDEINEQLT--IAKLSSSAFESQIQAYKMELQASQQKESSLNA 69 Query: 756 KIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSE 815 I E N E++L++ K +M D +++ +++ S L+ + +Y + Sbjct: 70 FIDEMMKEKMNFETKLNEQKQ----------IMTDNNEKIKQLNNEI-STLKLENSSYEQ 118 Query: 816 YTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQH 875 +++N D+++E Q I+ +NKE + E + L+ + +Q + Sbjct: 119 KVNDLMQIINLAPSNPAQDQILELQRT-IKQQNKEQNYLIEAFDIEKKELEEQIKKLQSN 177 Query: 876 YNALVEKANRTDLA-ESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNT 934 N + + LA + E T + Q++DL++ L ++ +TLI KE ++E+ Sbjct: 178 SNN--SEIDSLLLAFQEEKTSLEAQIQDLKAQLAN--NDTETLINTFHKE----KLEYEE 229 Query: 935 QIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQ 994 ++ + D L ++ + E T L + E K+ + L ++ E + K ++ Sbjct: 230 KVNKLLVDNDKLQKELKNKDEEQTSLLQAISEDKDKLSKLFDETQKQLNEEKENLKKQLK 289 Query: 995 KQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFT 1054 Q + Q I + +++ D + L QK+ + Q + + S+ E KL+ Sbjct: 290 LLNEQLENEKLQAKESIKAKDLVIQVIDSQRSELEQKLKD-QEDIIKIKSENEVKLSDEI 348 Query: 1055 TKLENMEEEMQRVSKQLL---DSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEG 1111 +L N +EMQ S L +S+ +++ ++ E D + L E+++ K + Sbjct: 349 QRLNNSIKEMQNNSNSSLSDLNSQISSQQQKLNQYEAQDVQSQATIKSLQTEIDVLKQKE 408 Query: 1112 MIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQEC 1171 + + I + D K+++ EE Q S E+ + E+ + Sbjct: 409 TNLQNLISEQDEKLAKQDQAIKDSQD-----KIKQLEEAAQNHS---EEEKEKQFEIIQM 460 Query: 1172 YTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNL--LSTVAELRSSISSAVD 1229 TK + + L + + + NQE+ Q++ ++ L+ EN+N + + + + + Sbjct: 461 ITK--ENDDLKAQNSEYVKQNQEKDRQIEELVQSLSNENNNNADIQKLYKEKEETELLIS 518 Query: 1230 QRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTM 1289 Q G EI +L Q+ E+ QL+ E+++++V + NKI + Sbjct: 519 QLGDEITQL--------NTKIQEKVDEVN-QLTETILDKEEVINAVTKDNSDLNNKIAEL 569 Query: 1290 EQ-VTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXX 1348 ++ + ++ +KEE + L K ++ N I+ E E+E F Sbjct: 570 NNAISEMTKEITEKEEKINELNRKIEELNNVIK----EKEEEINRFSSKISELNESINEK 625 Query: 1349 XXDLRTENQSYKQMQEQ---SILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLEL 1405 ++ N + ++ Q INE N Q ++ V E K EL Sbjct: 626 INEINNTNTAINELNNQIKEKDEKINELNNQNQEKQNKIDELNELNNT-VQQNETKFGEL 684 Query: 1406 THQLELKDSEIYQKTHEY---TITLTQRNDEFENVRQQLVEYEKRIEDLT-YEKESELAI 1461 + K++ I + E + ++++ N+ + L+E + I KE + ++ Sbjct: 685 NKENREKENRINELNKEIERINNSSSEKDKTIANLNESLLEKDNEITKKDELIKELQESV 744 Query: 1462 LRLKMHENANHYETMQKESEIERV-KLIEELNVKITESVSLNKQVAELNKALEEEV---- 1516 + N + ++I+ + + I ELN +I++ + K++ + LEE V Sbjct: 745 QTKETEINQKNELISSNNTKIDELNQQINELNAQISDKENSLKEITDKVHTLEETVQNKE 804 Query: 1517 AKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTM 1576 + N+ L +E +I LN+ I+ + ++ + +I + S + Q Q+ N Sbjct: 805 TEINQKNEELSERETKINELNEIISQKDSEIQQKNEEISSNNSKIEELNQ----QISNKE 860 Query: 1577 N--KELLDAVPRAE 1588 N +EL D V E Sbjct: 861 NSLQELTDKVHSLE 874 Score = 102 bits (245), Expect = 7e-20 Identities = 159/791 (20%), Positives = 328/791 (41%), Gaps = 72/791 (9%) Query: 222 QENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQX 281 Q+ + ++ K + + IE+ D+ LEE K L++ ++ LA + E+ Sbjct: 136 QDQILELQRTIKQQNKEQNYLIEAFDIEKKELEEQIKKLQSNSNNSEIDSLLLAFQ-EEK 194 Query: 282 XXXXXXXXXXXXXLAKQSIEPSC----EEKTEIEEKGSLEIANMTELTKKIELLEHLNCQ 337 LA E +EK E EEK + + + +L K+++ + Sbjct: 195 TSLEAQIQDLKAQLANNDTETLINTFHKEKLEYEEKVNKLLVDNDKLQKELKNKDEEQTS 254 Query: 338 IRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQD 397 + Q E ++KL+ + E++ + K+ N ++K QL +E L Sbjct: 255 LLQAISEDKDKLSKLFDETQKQLNEEKE-----------NLKKQLKLLNEQLENEKLQAK 303 Query: 398 TDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQ 457 K I ++ L + L D+E +I K + I ++Q Sbjct: 304 ESIKAKDLVIQVIDSQRSELEQKLKDQEDIIKIKSENEVKLSDEIQRLNNSIKEMQNNSN 363 Query: 458 QHMEGPSLIHVGTNTEDVN--EIAKVQEQLK-QELNDEI-----KDVNVKDLI----EKL 505 + + + + + +N E VQ Q + L EI K+ N+++LI EKL Sbjct: 364 SSLSDLN-SQISSQQQKLNQYEAQDVQSQATIKSLQTEIDVLKQKETNLQNLISEQDEKL 422 Query: 506 KSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQ-KTIDNFSKVSD----SNKEIVRL 560 ++ I D+I K + + NH + K+ Q + I +K +D N E V+ Sbjct: 423 AKQDQAIKDSQDKI----KQLEEAAQNHSEEEKEKQFEIIQMITKENDDLKAQNSEYVKQ 478 Query: 561 TEE----LHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAI 616 +E + L Q ++ ++Q + + ++ S + ++ ++ + ++ + Sbjct: 479 NQEKDRQIEELVQSLSNENNNNADIQKLYKEKEETELLISQLGDEITQLNTKIQEKVDEV 538 Query: 617 SLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKK 676 + L D + ++ + + ++ +K+A+++ S ++ EI EE+I+ L+ + Sbjct: 539 NQLTETILDKEEVINAVTKDNSDLNNKIAELNNAIS-EMTKEI--TEKEEKINELNRKIE 595 Query: 677 ELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELL 736 EL VI+ + + + I +L + +N++ N +L +++ K EKI+EL Sbjct: 596 ELNNVIKEKEEEINRFSSKISELNESINEKINEINNTNTAINELNNQI-KEKDEKINELN 654 Query: 737 AKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLE 796 + N E+Q+KI ++ +Q+ + + E + ++RI L + I + + + Sbjct: 655 NQ-NQEKQNKIDELNELNNTVQQNETKFGELNKENREKENRINELNKEIERINNSSSEKD 713 Query: 797 RKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQ 856 + L L EK +E T ++DEL+ L V+ + EI +N+ + N Sbjct: 714 KTIANLNESLLEKD---NEIT-KKDELIKEL------QESVQTKETEINQKNELISSNNT 763 Query: 857 ILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQT 916 + E NQ + + + N+L E ++ E +T++ L Sbjct: 764 KIDELNQQINELNAQISDKENSLKEITDKVHTLEETVQNKETEINQKNEELS-------- 815 Query: 917 LIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNM 976 +++ +I +L E +Q +S I+ K NE+ N + +L Q+ +N+++ L Sbjct: 816 ---ERETKINELN-EIISQKDSEIQQK---NEEISSNNSKIEELNQQISNKENSLQELTD 868 Query: 977 NVEELNKMNLE 987 V L N E Sbjct: 869 KVHSLETKNSE 879 Score = 86.2 bits (204), Expect = 7e-15 Identities = 132/680 (19%), Positives = 299/680 (43%), Gaps = 68/680 (10%) Query: 173 LDLQEKIN----EKDQII-EAKNK--ATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENF 225 L+ +EK+N + D++ E KNK T ++T++Q+ + +EN Sbjct: 225 LEYEEKVNKLLVDNDKLQKELKNKDEEQTSLLQAISEDKDKLSKLFDETQKQLNEEKENL 284 Query: 226 IA----MEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAAR------FEISLEHS-KL 274 + + ++EK + + I++KD+ I ++ LE +I E+ KL Sbjct: 285 KKQLKLLNEQLENEKLQAKESIKAKDLVIQVIDSQRSELEQKLKDQEDIIKIKSENEVKL 344 Query: 275 AQELEQXXXXXXXXXXXX-XXLAKQSIEPSCEEK--TEIEEKGSLEIANMTELTKKIELL 331 + E+++ L+ + + S +++ + E + A + L +I++L Sbjct: 345 SDEIQRLNNSIKEMQNNSNSSLSDLNSQISSQQQKLNQYEAQDVQSQATIKSLQTEIDVL 404 Query: 332 EHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSS 391 + ++ E + KLA + +A+ K L ++ +N + + K ++ Sbjct: 405 KQKETNLQNLISEQDEKLAK---QDQAIKDSQDKIKQL--EEAAQNHSEEEKEKQFEIIQ 459 Query: 392 ETLNQDTDKKINKNEIAK--------LEMVIQSL---NKDLVDKEYVISEKDTXXXXXXX 440 ++ D K +E K +E ++QSL N + D + + EK+ Sbjct: 460 MITKENDDLKAQNSEYVKQNQEKDRQIEELVQSLSNENNNNADIQKLYKEKEETELLISQ 519 Query: 441 XXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVN--V 498 G + I QL + Q+ ++ + + D E+ + +LN++I ++N + Sbjct: 520 L--GDE--ITQLNTKIQEKVD--EVNQLTETILDKEEVINAVTKDNSDLNNKIAELNNAI 573 Query: 499 KDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNH----KLKLKQMQKTI-DNFSKVSDS 553 ++ +++ EE+I +LN +I+ N N+IK K K+ ++ ++I + ++++++ Sbjct: 574 SEMTKEITEKEEKINELNRKIEELN-NVIKEKEEEINRFSSKISELNESINEKINEINNT 632 Query: 554 NKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDS-GRMIES------DVYKKMIEME 606 N I L ++ +K+ EL + Q + + + ++ ++ K+ E E Sbjct: 633 NTAINELNNQIKEKDEKINELNNQNQEKQNKIDELNELNNTVQQNETKFGELNKENREKE 692 Query: 607 NLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSD-QVCSEIKSVHLE 665 N K I + + + + + L + E ++++ +L + Q + K + Sbjct: 693 NRINELNKEIERINNSSSEKDKTIANLNESLLEKDNEITKKDELIKELQESVQTKETEIN 752 Query: 666 EQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLE 725 ++ + +S++ + I+ L +L I D EN ++I +K+ ++E + + Sbjct: 753 QKNELISSNNTK----IDELNQQINELNAQISDKENSLKEITDKVHT-LEETVQNKETEI 807 Query: 726 KMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESI 785 E++SE KIN E ++I +Q D++IQ+++ I + S++ + +I E S+ Sbjct: 808 NQKNEELSERETKIN--ELNEIISQK--DSEIQQKNEEISSNNSKIEELNQQISNKENSL 863 Query: 786 AVMEDRRYSLERKADQLGSY 805 + D+ +SLE K + SY Sbjct: 864 QELTDKVHSLETKNSEHRSY 883 Score = 69.7 bits (163), Expect = 6e-10 Identities = 111/508 (21%), Positives = 201/508 (39%), Gaps = 48/508 (9%) Query: 96 NTLKQKEILMEKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKD 155 N +K + + KE+ S++++ + DV + TIK Sbjct: 340 NEVKLSDEIQRLNNSIKEMQNNSNSSLSDLNSQISSQQQKLNQYEAQDVQSQA-TIKSLQ 398 Query: 156 NALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTK 215 + VL+ K ++ I + EK+ ++DQ I+ + Sbjct: 399 TEIDVLKQKETNLQNLISEQDEKLAKQDQAIKDSQDKIKQLEEAAQNHSEEEKEKQFEII 458 Query: 216 QQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEAN---KLLEAARFEISLEHS 272 Q +TK ++ A +E+ + Q + IE +S+ N + L + E L S Sbjct: 459 QMITKENDDLKAQNSEYVKQNQEKDRQIEELVQSLSNENNNNADIQKLYKEKEETELLIS 518 Query: 273 KLAQELEQXXXXXXXXXXXXXXLA------KQSIEPSCEEKTEIEEK-GSLE--IANMT- 322 +L E+ Q L ++ I ++ +++ K L I+ MT Sbjct: 519 QLGDEITQLNTKIQEKVDEVNQLTETILDKEEVINAVTKDNSDLNNKIAELNNAISEMTK 578 Query: 323 ELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTA--- 379 E+T+K E + LN +I + N ++ K + S +S ++ + I+ + NTA Sbjct: 579 EITEKEEKINELNRKIEELNNVIKEKEEEINRFSSKISELNESINEKINEINNTNTAINE 638 Query: 380 --SKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQ-------SLNKDLVDKEYVISE 430 +++K ++ +E NQ+ +K+ +E+ +L +Q LNK+ +KE I+E Sbjct: 639 LNNQIKEKDEKI-NELNNQNQEKQNKIDELNELNNTVQQNETKFGELNKENREKENRINE 697 Query: 431 KDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELN 490 + KD IA L SL+ E NEI K E +K EL Sbjct: 698 LNKEIERINNSSSEKDKTIANL---------NESLL------EKDNEITKKDELIK-ELQ 741 Query: 491 DEI--KDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFS 548 + + K+ + E + S +I +LN +I+ N I K N ++ T++ Sbjct: 742 ESVQTKETEINQKNELISSNNTKIDELNQQINELNA-QISDKENSLKEITDKVHTLE--E 798 Query: 549 KVSDSNKEIVRLTEELHHLSQKVAELEE 576 V + EI + EEL K+ EL E Sbjct: 799 TVQNKETEINQKNEELSERETKINELNE 826 Score = 54.0 bits (124), Expect = 3e-05 Identities = 59/292 (20%), Positives = 120/292 (41%), Gaps = 12/292 (4%) Query: 143 DVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXX 202 D + L+N I E +NA+S + ++ E I +L KI E + +I+ K + Sbjct: 558 DNSDLNNKIAELNNAISEMTKEITEKEEKINELNRKIEELNNVIKEKEEEINRFSSKISE 617 Query: 203 XXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEK-QRLLKDIESKDVRISSLEEANKLLE 261 + T + E + + + KDEK L + K +I L E N ++ Sbjct: 618 LNESINEKINEINNTNTAINE--LNNQIKEKDEKINELNNQNQEKQNKIDELNELNNTVQ 675 Query: 262 AARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANM 321 + + +L +E + + S E ++KT SL + Sbjct: 676 ----QNETKFGELNKENREKENRINELNKEIERINNSSSE---KDKTIANLNESL-LEKD 727 Query: 322 TELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGR-NTAS 380 E+TKK EL++ L ++ E+ K + + + + +++ + L ++ S + N+ Sbjct: 728 NEITKKDELIKELQESVQTKETEINQKNELISSNNTKIDELNQQINELNAQISDKENSLK 787 Query: 381 KMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKD 432 ++ L N++T+ E+++ E I LN+ + K+ I +K+ Sbjct: 788 EITDKVHTLEETVQNKETEINQKNEELSERETKINELNEIISQKDSEIQQKN 839 >UniRef50_UPI00006CA4F0 Cluster: Viral A-type inclusion protein repeat containing protein; n=1; Tetrahymena thermophila SB210|Rep: Viral A-type inclusion protein repeat containing protein - Tetrahymena thermophila SB210 Length = 1004 Score = 131 bits (317), Expect = 1e-28 Identities = 197/1005 (19%), Positives = 434/1005 (43%), Gaps = 77/1005 (7%) Query: 562 EELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLA-ETRLKAISLLE 620 + L L ++V LE++ + + D E YK E E + E+ +K S LE Sbjct: 6 DSLDSLKKQVKTLEKQLADQERKAAMNDKKAQKEVSKYKLDAEKEKIEKESLIKERSELE 65 Query: 621 SQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHL----EEQIDALSASK- 675 D V++L+I K + DK +D +Q + + EI+ ++L E + L S+ Sbjct: 66 ----DKVRKLNIELNKSSK--DKKSDENQTIINNLKKEIEKLNLMKPSPEMLAMLEMSEA 119 Query: 676 ---KELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKI 732 +EL +NL+ D ++ I+ L+ D + + N +Q+ + ++L++++ Sbjct: 120 PTYQELFRNFQNLQNDNKKQEEEIEKLKKGAIDSIVEKTNELQQKVKQIEELQELNQSLE 179 Query: 733 SELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRR 792 L K N E +++ Q +Q + E +E EL + K + + +E + E+ R Sbjct: 180 RSL--KDNDYENQQMRDQL---RSVQSENNKAELLEEELKQIKVTLQQKDEQL---ENLR 231 Query: 793 YSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQ 852 +E++ + L ++Q E I+++ V+ ++ + + + + KEL Sbjct: 232 QEVEKQQQKFQDQLTQEQSLKEEAIIEKER-----EVIKSYEEKMHEIDSQFRNNEKELL 286 Query: 853 KKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITH 912 ++ + E+ +N ++ +++ + + K +T + E KYQ ++++LE+ + Sbjct: 287 QELRQCEEKLKNAELQAQSLEEEKQS-ISKGQKTQSDKIE-LKYQQKIKELEAQMDETQS 344 Query: 913 EHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIE 972 H+ ++ K++ E++ ++ ++ I + LNE+ E+ ++ E + QE I+ Sbjct: 345 YHEKILSTTKQQYENMILQQEQSMQKQIDE---LNEQIEQLQKHNNSQEGKSQEANEAIK 401 Query: 973 NLNMNVEELNKMNLEL---IDKHVQKQQTQSPDYTE-------QYINEINKLNAL---LK 1019 +++L +E ++ +Q+ + Q ++ + Q + EI++L Sbjct: 402 AKEEQIKKLEDQIIEKQEQLETKIQEYEAQIFEFNKKHKEENSQLLAEIDRLKIYEEKFH 461 Query: 1020 QKDEEIIALNQKI-----NNAQVSYMSMVSDYESKL---AQFT---TKLENMEEEMQRVS 1068 QK + + NQ++ + S SM SD + + A+F ++ E +E+ ++ Sbjct: 462 QKKQAADSFNQELKKMIRDRRSSSSFSMNSDSDETMDVKAEFEKIRSEFEKVEQLNEKYE 521 Query: 1069 KQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNV 1128 +++ + ++ EQ+ +I+E + E I + + I SS I+ +A N+ Sbjct: 522 QEIAEKNAEISAFSEIITEQEKKIQEKTNLIIQNEKEIDQFKAEIESSAIKLKEKEA-NI 580 Query: 1129 DXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGH 1188 + L Q +++ ++ + + + L L +I QL NTEL Sbjct: 581 ENLKSQIKNATSSLTEQSDKQILELTEKSKAEISHLQDTLTAKLQEIKQLNAKNTELQQQ 640 Query: 1189 DVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREA 1248 + Q ++Q K + E + NL ++ L+ ++Q ++ E +Q +++ Sbjct: 641 NQNLQSAVDQNKHETESQLKKEQNLQQQISHLK----QLIEQSEAQLNEKNEQLTSEKNQ 696 Query: 1249 DFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRN 1308 + L+ Q+ +S QL D + S T + + ++++T + +L ++ + LR Sbjct: 697 N-----KSLKEQVINEKSSQNQLSDEIASLTAQNCDMEQKIKEMTVKEQQLFEESKELRT 751 Query: 1309 LQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSIL 1368 I Q E E +K L++E KQ E+ Sbjct: 752 KLSNLETKIQQSE----ETLTKKNEALEKIKQEKKQILSETEGLKSEISQLKQNLEKQKN 807 Query: 1369 NINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTI-TL 1427 I E+ Q+ + + + ++ L QL L E K ++ I L Sbjct: 808 EIQEKQEQVNRLTQQIESQKSQENEMKQNLNKQIQAL--QLSLSKEEAIIKQNDSDIANL 865 Query: 1428 TQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHEN-ANHYETMQKESEIERVK 1486 ++ + E ++Q+ + + E + K+ EL +L+ EN N + ++ +E+ + Sbjct: 866 KEKIAQKEEEKKQIQKKLAQNEGVDV-KQIELFQSQLEEKENQINQLKDQIQDMNLEQEQ 924 Query: 1487 LIEELNVKITE-SVSLNKQVAELNKALEEEVAKTNEMQTALENQE 1530 ++ ELN +I +V + + ++N + E + N++Q+ LE E Sbjct: 925 VVYELNKQINALNVEIKQLNLKINSSEELFQQEKNQLQSELEYAE 969 Score = 128 bits (310), Expect = 9e-28 Identities = 218/1005 (21%), Positives = 432/1005 (42%), Gaps = 114/1005 (11%) Query: 626 LVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENL 685 L +++ L+++ + E K A ++ ++ + S+ K +E+I+ S K+ L + Sbjct: 11 LKKQVKTLEKQLADQERKAA-MNDKKAQKEVSKYKLDAEKEKIEKESLIKERSELEDKVR 69 Query: 686 KLDKEQLYGTIKDLENDK-EDIMNKLQ------NYIQENMDLTDKLEKMSAEKISELLAK 738 KL+ E L + KD ++D+ + I+N L+ N ++ + ++ LE A EL Sbjct: 70 KLNIE-LNKSSKDKKSDENQTIINNLKKEIEKLNLMKPSPEMLAMLEMSEAPTYQELFRN 128 Query: 739 I-NHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKS--RICRLEESIA-VMEDRRYS 794 N + +K Q + K D +E K K + L +S+ ++D Y Sbjct: 129 FQNLQNDNKKQEEEIEKLKKGAIDSIVEKTNELQQKVKQIEELQELNQSLERSLKDNDYE 188 Query: 795 LERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKK 854 ++ DQL S E KA + E+EL L D +E E+E + ++ Q Sbjct: 189 NQQMRDQLRSVQSENNKA----ELLEEELKQIKVTLQQKDEQLENLRQEVEKQQQKFQ-- 242 Query: 855 NQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQ-LRDLESNLKRITHE 913 +Q+ E++ + + ++ + EK + D + K Q LR E LK + Sbjct: 243 DQLTQEQSLKEEAIIEKEREVIKSYEEKMHEIDSQFRNNEKELLQELRQCEEKLKNAELQ 302 Query: 914 HQTLIVQKKKEIEDLEIEFNTQIESAIRDK-KVLNEKYEKNIEYVTQ-LEAQLQEYKNNI 971 Q+L ++K+ I + + +IE + K K L + ++ Y + L Q+Y+N I Sbjct: 303 AQSL-EEEKQSISKGQKTQSDKIELKYQQKIKELEAQMDETQSYHEKILSTTKQQYENMI 361 Query: 972 ----ENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIA 1027 +++ ++ELN+ +E + KH Q+ +S + N +K K+E+I Sbjct: 362 LQQEQSMQKQIDELNEQ-IEQLQKHNNSQEGKSQE-----------ANEAIKAKEEQIKK 409 Query: 1028 LNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVRE 1087 L +I Q + + +YE+++ +F K +EE ++ ++ K + E+ + Sbjct: 410 LEDQIIEKQEQLETKIQEYEAQIFEFNKK---HKEENSQLLAEIDRLKIYEEKFHQKKQA 466 Query: 1088 QDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEE 1147 D +ELK K+ + SS+ SD +D K++ E Sbjct: 467 ADSFNQELK--KMIRDRRS--------SSSFSMNSDSDETMDVKAEFE-------KIRSE 509 Query: 1148 EEFIQERSVLQEQS-AKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKS----- 1201 E +++ + EQ A+ N E+ I + E E T + N+++I+Q K+ Sbjct: 510 FEKVEQLNEKYEQEIAEKNAEISAFSEIITEQEKKIQEKTNLIIQNEKEIDQFKAEIESS 569 Query: 1202 --KLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRV 1259 KL++ +NL S + SS++ D++ E+ E K ++ + E++ Sbjct: 570 AIKLKEKEANIENLKSQIKNATSSLTEQSDKQILELTEKSKAEISHLQDTLTAKLQEIK- 628 Query: 1260 QLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQ 1319 QL+A ++ +Q ++QS+ + NK T Q+ QN LQ + HL+ L I Q Sbjct: 629 QLNAKNTELQQQNQNLQSAVDQ--NKHETESQLKKEQN-LQQQISHLKQL-------IEQ 678 Query: 1320 IEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKK 1379 E +E ++ L +E K ++EQ ++N QL Sbjct: 679 SEAQLNEKNEQ---------------------LTSEKNQNKSLKEQ-VINEKSSQNQLSD 716 Query: 1380 SSXXXXXXXXXXXXRVNDA---EAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFEN 1436 ++ + E ++ E + +L K S + K + TLT++N+ E Sbjct: 717 EIASLTAQNCDMEQKIKEMTVKEQQLFEESKELRTKLSNLETKIQQSEETLTKKNEALEK 776 Query: 1437 VRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERV-KLIEELNVKI 1495 ++Q+ +K+I T +SE++ L+ + + N E +K+ ++ R+ + IE + Sbjct: 777 IKQE----KKQILSETEGLKSEISQLKQNLEKQKN--EIQEKQEQVNRLTQQIESQKSQE 830 Query: 1496 TE-SVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKI 1554 E +LNKQ+ L +L +E A + + + N + +I +E +Q + + Sbjct: 831 NEMKQNLNKQIQALQLSLSKEEAIIKQNDSDIANLKEKIAQKEEEKKQIQKKLAQNEGVD 890 Query: 1555 QKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDLAMYMLHQR 1599 K + + ++ Q+ N + ++ D E + +Y L+++ Sbjct: 891 VKQIELFQSQLEEKENQI-NQLKDQIQDM--NLEQEQVVYELNKQ 932 Score = 120 bits (289), Expect = 3e-25 Identities = 177/919 (19%), Positives = 406/919 (44%), Gaps = 71/919 (7%) Query: 233 KDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQE--LEQXXXXXXXXXX 290 K + + L K + ++ R +++ + E +++++ E K+ +E +++ Sbjct: 12 KKQVKTLEKQLADQE-RKAAMNDKKAQKEVSKYKLDAEKEKIEKESLIKERSELEDKVRK 70 Query: 291 XXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLA 350 L K S + +E I EI + + E+L L T +EL Sbjct: 71 LNIELNKSSKDKKSDENQTIINNLKKEIEKLNLMKPSPEMLAMLEMSEAPTYQELFRNFQ 130 Query: 351 TMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSS-ETLNQDTDKKINKNEIAK 409 + ++K +K T ++++ Q+ + LNQ ++ + N+ Sbjct: 131 NLQNDNKKQEEEIEKLKKGAIDSIVEKT-NELQQKVKQIEELQELNQSLERSLKDNDYEN 189 Query: 410 LEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVG 469 +M Q + + + + E++ + + ++E QQ L Sbjct: 190 QQMRDQLRSVQSENNKAELLEEELKQIKVTLQQKDEQLENLRQEVEKQQQKFQDQLTQEQ 249 Query: 470 TNTEDV-----NEIAKVQEQLKQELNDEIKDVNVKDLI-------EKLKSAEEQITQLND 517 + E+ E+ K E+ E++ + ++ N K+L+ EKLK+AE Q L + Sbjct: 250 SLKEEAIIEKEREVIKSYEEKMHEIDSQFRN-NEKELLQELRQCEEKLKNAELQAQSLEE 308 Query: 518 EIDAANKNMI----KVKSNHKLKLKQMQKTIDN----FSKVSDSNKEIVR--LTEELHHL 567 E + +K K++ ++ K+K+++ +D K+ + K+ + ++ + Sbjct: 309 EKQSISKGQKTQSDKIELKYQQKIKELEAQMDETQSYHEKILSTTKQQYENMILQQEQSM 368 Query: 568 SQKVAELEEEKGNLQLHLVDYDSGRMIESDVYK-KMIEMENLAETRLKAISLLESQKFDL 626 +++ EL E+ LQ H + ++ K K +++ L + ++ LE++ + Sbjct: 369 QKQIDELNEQIEQLQKHNNSQEGKSQEANEAIKAKEEQIKKLEDQIIEKQEQLETKIQEY 428 Query: 627 VQELHILQQKYDEVEDKL-ADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENL 685 ++ +K+ E +L A+I +L+ + + H ++Q A + +EL +I + Sbjct: 429 EAQIFEFNKKHKEENSQLLAEIDRLKIYE-----EKFHQKKQ--AADSFNQELKKMIRDR 481 Query: 686 KLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLA--KINHEE 743 + + D D + K+++ ++ L +K E+ AEK +E+ A +I E+ Sbjct: 482 RSSSSFSMNSDSDETMDVKAEFEKIRSEFEKVEQLNEKYEQEIAEKNAEISAFSEIITEQ 541 Query: 744 QSKIQTQFGIDAKIQ-ERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQL 802 + KIQ + + + + E D + IES K K + +E + +++ SL ++D+ Sbjct: 542 EKKIQEKTNLIIQNEKEIDQFKAEIESSAIKLKEKEANIENLKSQIKNATSSLTEQSDKQ 601 Query: 803 GSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQK-------KN 855 L EK KA E + +D L +L + + + + E++ +N+ LQ + Sbjct: 602 ILELTEKSKA--EISHLQDTLTAKLQEI----KQLNAKNTELQQQNQNLQSAVDQNKHET 655 Query: 856 QILLEENQNLQISLSDMQQHYNA----LVEKANRTDLAESESTKYQTQLRDLESNLKRIT 911 + L++ QNLQ +S ++Q L EK + ++++ + Q+ + +S+ +++ Sbjct: 656 ESQLKKEQNLQQQISHLKQLIEQSEAQLNEKNEQLTSEKNQNKSLKEQVINEKSSQNQLS 715 Query: 912 HEHQTLIVQK---KKEIEDLEIEFNTQIESA--IRDK-KVLNEKYEKNIEYVTQLEAQLQ 965 E +L Q +++I+++ ++ E + +R K L K +++ E +T+ L+ Sbjct: 716 DEIASLTAQNCDMEQKIKEMTVKEQQLFEESKELRTKLSNLETKIQQSEETLTKKNEALE 775 Query: 966 EYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEI 1025 + K + + E L K + + ++++KQ+ + + EQ ++ + Q++E Sbjct: 776 KIKQEKKQILSETEGL-KSEISQLKQNLEKQKNEIQEKQEQVNRLTQQIESQKSQENEMK 834 Query: 1026 IALNQKINNAQVSYM---SMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSK----QHN 1078 LN++I Q+S +++ +S +A K+ EEE +++ K+L ++ + Sbjct: 835 QNLNKQIQALQLSLSKEEAIIKQNDSDIANLKEKIAQKEEEKKQIQKKLAQNEGVDVKQI 894 Query: 1079 EELQILVREQDDQIKELKE 1097 E Q + E+++QI +LK+ Sbjct: 895 ELFQSQLEEKENQINQLKD 913 Score = 106 bits (254), Expect = 6e-21 Identities = 166/828 (20%), Positives = 361/828 (43%), Gaps = 65/828 (7%) Query: 298 QSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESK 357 QS+E S ++ ++ ++ ++ K ELLE QI+ T ++ + +L + E + Sbjct: 176 QSLERSLKDNDYENQQMRDQLRSVQSENNKAELLEEELKQIKVTLQQKDEQLENLRQEVE 235 Query: 358 AVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNE---IAKLEMVI 414 K L +S + A K S E + D + NE + +L Sbjct: 236 --KQQQKFQDQLTQEQSLKEEAIIEKEREVIKSYEEKMHEIDSQFRNNEKELLQELRQCE 293 Query: 415 QSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIH---VGTN 471 + L + + + EK + + Q E + M+ H + T Sbjct: 294 EKLKNAELQAQSLEEEKQSISKGQKTQSDKIELKYQQKIKELEAQMDETQSYHEKILSTT 353 Query: 472 TEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKS 531 + + QEQ Q+ DE+ + ++ L + S E + + N+ I A + + K++ Sbjct: 354 KQQYENMILQQEQSMQKQIDELNE-QIEQLQKHNNSQEGKSQEANEAIKAKEEQIKKLED 412 Query: 532 NHKLKLKQMQKTIDNF-SKVSDSNKEIVRLTEELHHLSQKVAELE--EEKGNLQLHLVD- 587 K +Q++ I + +++ + NK + EE L ++ L+ EEK + + D Sbjct: 413 QIIEKQEQLETKIQEYEAQIFEFNK---KHKEENSQLLAEIDRLKIYEEKFHQKKQAADS 469 Query: 588 --YDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYD-EVEDKL 644 + +MI M + ++ + + E + + +++ L +KY+ E+ +K Sbjct: 470 FNQELKKMIRDRRSSSSFSMNSDSDETMDVKAEFEKIRSEF-EKVEQLNEKYEQEIAEKN 528 Query: 645 ADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKE 704 A+IS S+ + + K + +E+ + + ++KE I+ K + E +K+ E + E Sbjct: 529 AEISAF-SEIITEQEKKI--QEKTNLIIQNEKE----IDQFKAEIESSAIKLKEKEANIE 581 Query: 705 DIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQS---KIQTQFGIDAKIQERD 761 ++ ++++N LT++ +K E + A+I+H + + K+Q ++AK E Sbjct: 582 NLKSQIKN---ATSSLTEQSDKQILELTEKSKAEISHLQDTLTAKLQEIKQLNAKNTELQ 638 Query: 762 LYIENIESELSKYK----SRICR---LEESIA----VMEDRRYSLERKADQLGSYLQEKQ 810 +N++S + + K S++ + L++ I+ ++E L K +QL S + + Sbjct: 639 QQNQNLQSAVDQNKHETESQLKKEQNLQQQISHLKQLIEQSEAQLNEKNEQLTSE-KNQN 697 Query: 811 KAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLS 870 K+ E I E N+L+ D + Q ++E + KE+ K Q L EE++ L+ LS Sbjct: 698 KSLKEQVINEKSSQNQLS---DEIASLTAQNCDMEQKIKEMTVKEQQLFEESKELRTKLS 754 Query: 871 DM----QQHYNALVEKANRTDLAESESTKYQTQLRDLE---SNLKRITHEHQTLIVQKKK 923 ++ QQ L +K + + E + ++ L+ S LK+ + + I +K++ Sbjct: 755 NLETKIQQSEETLTKKNEALEKIKQEKKQILSETEGLKSEISQLKQNLEKQKNEIQEKQE 814 Query: 924 EIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNK 983 ++ L + +Q K+ LN++ + +++ EA +++ ++I NL + + + Sbjct: 815 QVNRLTQQIESQKSQENEMKQNLNKQIQALQLSLSKEEAIIKQNDSDIANLKEKIAQKEE 874 Query: 984 MNLELIDKHVQ------KQQTQSPDYTEQYINEINKLNALLK----QKDEEIIALNQKIN 1033 ++ K Q KQ E+ N+IN+L ++ ++++ + LN++IN Sbjct: 875 EKKQIQKKLAQNEGVDVKQIELFQSQLEEKENQINQLKDQIQDMNLEQEQVVYELNKQIN 934 Query: 1034 NAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEEL 1081 V + S F + ++ E++ +++K + E+ Sbjct: 935 ALNVEIKQLNLKINSSEELFQQEKNQLQSELEYAESAAIEAKMNYAEV 982 Score = 37.1 bits (82), Expect = 4.0 Identities = 55/287 (19%), Positives = 120/287 (41%), Gaps = 15/287 (5%) Query: 147 LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXX 206 + IKE L + K + T + +L+ KI + ++ + KN+A Sbjct: 728 MEQKIKEMTVKEQQLFEESKELRTKLSNLETKIQQSEETLTKKNEA----LEKIKQEKKQ 783 Query: 207 XXXXXEDTKQQMTKMQENFIAMEAEWKDEKQ---RLLKDIESKDVRISSLEE-ANKLLEA 262 E K +++++++N + E +++++ RL + IES+ + + +++ NK ++A Sbjct: 784 ILSETEGLKSEISQLKQNLEKQKNEIQEKQEQVNRLTQQIESQKSQENEMKQNLNKQIQA 843 Query: 263 ARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMT 322 + +S E + + Q K+ I+ + ++ K +E+ + Sbjct: 844 LQLSLSKEEAIIKQ--NDSDIANLKEKIAQKEEEKKQIQKKLAQNEGVDVK-QIELF-QS 899 Query: 323 ELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKM 382 +L +K + L QI+ N E E + + + A++ K+ + I+ S + Sbjct: 900 QLEEKENQINQLKDQIQDMNLEQEQVVYELNKQINALNVEIKQLNLKIN--SSEELFQQE 957 Query: 383 KSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVIS 429 K+ + + K+N E+A + K+L KEY IS Sbjct: 958 KNQLQSELEYAESAAIEAKMNYAEVACERDYYECCYKNLC-KEYGIS 1003 >UniRef50_Q4Q3D8 Cluster: Putative uncharacterized protein; n=3; Leishmania|Rep: Putative uncharacterized protein - Leishmania major Length = 3167 Score = 131 bits (317), Expect = 1e-28 Identities = 219/1139 (19%), Positives = 460/1139 (40%), Gaps = 64/1139 (5%) Query: 213 DTKQQMTKMQENFIAMEAEW-KDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271 + + + K + +A E E ++E +RL +++ L + E ++ Sbjct: 1657 EEEAERQKAENRRLAAELERAQEEAERLAAELDRAQEEAEKLAADLEKAEEDAERQKADN 1716 Query: 272 SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELL 331 +LA + E+ LA +E + EE E ++ + +A EL + E Sbjct: 1717 RRLAADNERLAAELDRAQEEAERLAAD-LEKA-EEDAERQKADNERLA--AELDRAQEEA 1772 Query: 332 EHLNCQIRQTNKELENKLATMG-TESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLS 390 E L ++ + +E E A + + +A + K + A K+ + + Sbjct: 1773 ERLAAELEKAQEEAERLAAELEKAQEEAERQKADKERLAAELDRAQEEAEKLAADLEKAE 1832 Query: 391 SETLNQDTDKKI----NKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKD 446 E Q D + N+ A+LE + + + E E + + Sbjct: 1833 EEAERQKADNRRLAADNERLAAELERAQEEAERLAAELERAQEEAERLAAEVDRAQEEAE 1892 Query: 447 TLIAQLQL--EHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELND-EIKDVNVKDLIE 503 L A L+ E + + + N E+ + QE+ ++ + E + + L Sbjct: 1893 QLAADLEKAEEEAERQKADNRRLAADNERLAAELDRAQEEAERLAAELEKAEEEAERLAA 1952 Query: 504 KLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEE 563 +L+ A+E+ +L +++ A ++ + K++++ ++ + + +++ ++ R EE Sbjct: 1953 ELEKAQEEAERLAADLEKAEEDAERQKADNEQLAAELNRAQEEAKRLA---ADLERAQEE 2009 Query: 564 LHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQK 623 L+ ++ +EE L L E D ++ + E LA + + LE + Sbjct: 2010 AEKLAAELERAQEEAEKLAADL------EKAEEDAERQKADNERLAADNERLAAELERTQ 2063 Query: 624 FDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIE 683 + + L++ ++ E + AD QL ++ ++ ++ L ++ ++LA +E Sbjct: 2064 EEAEKLAADLEKAEEDAERQKADNEQLAAELNRAQEEAKRLAADLERAQEEAEKLAAELE 2123 Query: 684 NLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMS--AEKISELLAKINH 741 + + E+L ++ E D E + +N L +LE+ AEK++ L K Sbjct: 2124 RAQEEAEKLAADLEKAEEDAERQKADNRRLAADNERLAAELERTQEEAEKLAADLEKAEE 2183 Query: 742 EEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQ 801 E + + + A++ E + ++L K + E A E L R ++ Sbjct: 2184 EAERQKADNERLAAELDRAQEEAEKLAADLEKAEEDA---ERQKADNERLAAELNRAQEE 2240 Query: 802 LGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEE 861 + +KA + Q+ + A L E+ E+E +E +K L + Sbjct: 2241 AEKLAADLEKAEEDAERQKADNERLAAELNRAQEEAERLAAELERAQEEAEKLAADLEKA 2300 Query: 862 NQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQK 921 + + +D +Q L + +E K Q + L ++L++ E + ++ Sbjct: 2301 EEEAERQKADNEQLAAELNRAQEEAEKLAAELEKAQEEAEKLAADLEKAEEEAE----RQ 2356 Query: 922 KKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEEL 981 K + E L E N E A + L + E+ +LE +E + LN EE Sbjct: 2357 KADNERLAAELNRAQEEAEKLAAELEKAQEEAERLAAELEKAQEEAERLAAELNRAQEEA 2416 Query: 982 NKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMS 1041 ++ EL + Q++ + ++ E +L A L++ EE L ++N AQ Sbjct: 2417 ERLAAEL--ERAQEEAERLAAELDRAQEEAERLAAELERAQEEAERLAAELNRAQEEAEK 2474 Query: 1042 MVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLT 1101 + ++ E AQ + E + +R++ +L ++ EE + L E + +E + +L Sbjct: 2475 LAANLEK--AQ--EEAERQKAHNERLAAEL---ERAREEAERLAAELEKAQEEAE--RLA 2525 Query: 1102 FEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEE-EEFIQERSVLQEQ 1160 E+ + E +++ +E ++A + K QEE E E QE+ Sbjct: 2526 AELEKAREEAERLAAELERAREEAERLAAELE---------KAQEEAERLAAELDRAQEE 2576 Query: 1161 SAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNL---LSTV 1217 + KL +L++ + + + N L QE+ +L ++LE+ E + L L Sbjct: 2577 AEKLAADLEKAEEEAERQKADNERLAAELDRAQEEAERLAAELERAQEEAERLAAELDRA 2636 Query: 1218 AELRSSISSAVDQRGFEIAELWKQ-HLAQREADFQKTEHE-LRVQLSAFESKYEQLLDSV 1275 E +++ +D+ E +L A+ EA+ QK ++E L +L+ + + E+L + Sbjct: 2637 QEEAERLAAELDRAQEEAEKLAADLEKAEEEAERQKADNERLAAELNRAQEEAERLAAEL 2696 Query: 1276 QSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVIN-QIEILRSEIEDEKVA 1333 + + QEE K+ L+ +D E + + AD E+ R++ E E++A Sbjct: 2697 EKA-QEEAEKL-----AADLEKAEEDAERQKADNRRLAADNERLAAELDRAQEEAERLA 2749 Score = 131 bits (316), Expect = 2e-28 Identities = 279/1433 (19%), Positives = 547/1433 (38%), Gaps = 94/1433 (6%) Query: 147 LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXX 206 L +E + + L + E DL EK E+ + +A+N+ Sbjct: 1044 LERAQEEAERLAAELDRAQEEAEKLAADL-EKAEEEAERQKAENRRLAAELERAQEEAER 1102 Query: 207 XXXXXEDTKQQMTKMQENFIAMEAE---WKDEKQRLLKDIE---SKDVRISS-LEEANKL 259 + +++ K+ + E E K E +RL ++E + R+++ LE A + Sbjct: 1103 LAAELDRAQEEAEKLAADLEKAEEEAERQKAENRRLAAELERAQEEAERLAAELERAQEE 1162 Query: 260 LEAARFEISL---EHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSL 316 E E+ E KLA ELE+ A++ E E + +E+ Sbjct: 1163 AERLAAELDRAQEEAEKLAAELERAQEEAEKLAAELDR-AQEEAERLAAELEKAQEEAER 1221 Query: 317 EIANMTELTKKIELLEHLNCQIRQTNKELENKLATMG-TESKAVSSPSKKGSPLISRKSG 375 A EL K E E L ++ + +E E A + E A ++K Sbjct: 1222 LAA---ELEKTQEEAERLAAELEKAQEEAERLAADLEKAEEDAERQKAEKERLAAEVDRA 1278 Query: 376 RNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXX 435 + A K+ + + + Q D + E+ + + + L DL +K +E+D Sbjct: 1279 QEEAEKLAADLEKAEEDAERQKADNERLAAELNRAQEEAERLAADL-EK----AEEDAER 1333 Query: 436 XXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKD 495 D +LE Q + E+ +A E K E + E + Sbjct: 1334 QKADNRRLAADNERLAAELERAQEEAERLAAELDRAQEEAERLAADLE--KAEEDAERQK 1391 Query: 496 VNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNK 555 + + L +L A+E+ +L +++ A ++ + K++++ ++ +++ + + Sbjct: 1392 ADNERLAAELDRAQEEAEKLAADLEKAEEDAERQKADNERLAADNERLA---AELDRAQE 1448 Query: 556 EIVRLTEELHHLSQKVAELEEEKGNLQLHLVD-YDSGRMIESDVYKKMIEMENLAETRLK 614 E RL +L + + + L L + + +++ K E E LA K Sbjct: 1449 EAERLAADLEKAEEDAERQKADNERLAAELDRAQEEAERLAAELEKAQEEAERLAAELEK 1508 Query: 615 AISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSAS 674 A E QK D + L + +E E AD+ + + D + + L +++ Sbjct: 1509 AQEEAERQKADKERLAAELDRAQEEAEKLAADLEKAEEDAERQKADNERLAAELNRAQEE 1568 Query: 675 KKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISE 734 + LA +E + D E+ + L D E + +L+ +E L +LEK E + Sbjct: 1569 AERLAADLEKAEEDAERQKADNRRLAADNERLAAELERAQEEAERLAAELEKAQEEAERQ 1628 Query: 735 LLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYS 794 K + E + + +A+ DL E+E K ++R E A E R + Sbjct: 1629 ---KADKERLAAELDRAQEEAEKLAADLEKAEEEAERQKAENRRLAAELERAQEEAERLA 1685 Query: 795 LE-----RKADQLGSYLQ------EKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQL-- 841 E +A++L + L+ E+QKA + ++E RLA +D + ++L Sbjct: 1686 AELDRAQEEAEKLAADLEKAEEDAERQKADNRRLAADNE---RLAAELDRAQEEAERLAA 1742 Query: 842 -LEIEHENKELQK-KNQILLEENQNLQISLSDMQQHYNALVEKANR----TDLAESESTK 895 LE E+ E QK N+ L E Q + E+A R + A+ E+ + Sbjct: 1743 DLEKAEEDAERQKADNERLAAELDRAQEEAERLAAELEKAQEEAERLAAELEKAQEEAER 1802 Query: 896 YQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIE 955 + L + L R E + L +K E+ E + D + L + E+ E Sbjct: 1803 QKADKERLAAELDRAQEEAEKLAADLEKAEEEAERQ-KADNRRLAADNERLAAELERAQE 1861 Query: 956 YVTQLEAQLQEYKNNIENLNMNVEELNKMNLEL---IDKHVQKQQTQSPDYTEQYINEIN 1012 +L A+L+ + E L V+ + +L ++K ++ + Q D + + Sbjct: 1862 EAERLAAELERAQEEAERLAAEVDRAQEEAEQLAADLEKAEEEAERQKAD-NRRLAADNE 1920 Query: 1013 KLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLL 1072 +L A L + EE L ++ A+ + ++ E + ++E+ + +Q Sbjct: 1921 RLAAELDRAQEEAERLAAELEKAEEEAERLAAELEKAQEEAERLAADLEKAEEDAERQKA 1980 Query: 1073 DSKQHNEELQILVREQDDQIKELKET-----KLTFEMNIPKTEGMIISSTIEPMSDDANN 1127 D++Q EL E +L+ KL E+ + E +++ +E +DA Sbjct: 1981 DNEQLAAELNRAQEEAKRLAADLERAQEEAEKLAAELERAQEEAEKLAADLEKAEEDAER 2040 Query: 1128 VDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTG 1187 + E E QE++ KL +L++ + + N +L Sbjct: 2041 QKADNERLAA--------DNERLAAELERTQEEAEKLAADLEKAEEDAERQKADNEQLAA 2092 Query: 1188 HDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISS-AVD-QRGFEIAELWKQHLAQ 1245 QE+ +L + LE+ E + L + + + A D ++ E AE K + Sbjct: 2093 ELNRAQEEAKRLAADLERAQEEAEKLAAELERAQEEAEKLAADLEKAEEDAERQKADNRR 2152 Query: 1246 READFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEH 1305 AD ++ L +L + + E+L ++ + +E + E++ + ++ Q++ E Sbjct: 2153 LAADNER----LAAELERTQEEAEKLAADLEKAEEEAERQKADNERLAAELDRAQEEAEK 2208 Query: 1306 LRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQ 1365 L EK + + R + ++E++A + E+ ++ + Sbjct: 2209 LAADLEKAEE-----DAERQKADNERLAAELNRAQEEAEKLAADLEKAEEDAERQKADNE 2263 Query: 1366 SI---LNINEEN-----AQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIY 1417 + LN +E A+L+++ +AE + + QL + + Sbjct: 2264 RLAAELNRAQEEAERLAAELERAQEEAEKLAADLEKAEEEAERQKAD-NEQLAAELNRAQ 2322 Query: 1418 QKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQ 1477 ++ + L + +E E + L + E+ E + E A L + E A Sbjct: 2323 EEAEKLAAELEKAQEEAEKLAADLEKAEEEAERQKADNERLAAELN-RAQEEAEKLAAEL 2381 Query: 1478 KESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQE 1530 ++++ E +L EL E+ L AELN+A EE E++ A E E Sbjct: 2382 EKAQEEAERLAAELEKAQEEAERL---AAELNRAQEEAERLAAELERAQEEAE 2431 Score = 126 bits (304), Expect = 5e-27 Identities = 258/1379 (18%), Positives = 545/1379 (39%), Gaps = 90/1379 (6%) Query: 217 QMTKMQENFIAMEAEW---KDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSK 273 ++ + QE + AE ++E +RL D+E + + N+ L A E K Sbjct: 1351 ELERAQEEAERLAAELDRAQEEAERLAADLEKAEEDAERQKADNERLAAELDRAQEEAEK 1410 Query: 274 LAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEH 333 LA +LE+ LA + E E +E+ A++ + + E Sbjct: 1411 LAADLEKAEEDAERQKADNERLAADN-ERLAAELDRAQEEAERLAADLEKAEEDAE---- 1465 Query: 334 LNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSET 393 + + N+ L +L E++ +++ +K R + ++ ++ + E Sbjct: 1466 ---RQKADNERLAAELDRAQEEAERLAAELEKAQEEAERLAAELEKAQEEAERQKADKER 1522 Query: 394 LNQDTDKKINKNE--IAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXG--KDTLI 449 L + D+ + E A LE + + D E + +E + K Sbjct: 1523 LAAELDRAQEEAEKLAADLEKAEEDAERQKADNERLAAELNRAQEEAERLAADLEKAEED 1582 Query: 450 AQLQLEHQQHMEGPS---LIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLK 506 A+ Q + + + + E+ +A E+ ++E E + + + L +L Sbjct: 1583 AERQKADNRRLAADNERLAAELERAQEEAERLAAELEKAQEEA--ERQKADKERLAAELD 1640 Query: 507 SAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHH 566 A+E+ +L +++ A + + K+ ++ ++++ + +++ E+ R EE Sbjct: 1641 RAQEEAEKLAADLEKAEEEAERQKAENRRLAAELERAQEEAERLA---AELDRAQEEAEK 1697 Query: 567 LSQKVAELEE--EKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKF 624 L+ + + EE E+ + D+ R+ +++ + E E LA KA E QK Sbjct: 1698 LAADLEKAEEDAERQKADNRRLAADNERLA-AELDRAQEEAERLAADLEKAEEDAERQKA 1756 Query: 625 DLVQELHILQQKYDEVEDKLADISQLQ--SDQVCSEIKSVHLEEQIDALSASKKELALVI 682 D + L + +E E A++ + Q ++++ +E++ +E+ + A K+ LA + Sbjct: 1757 DNERLAAELDRAQEEAERLAAELEKAQEEAERLAAELEKA--QEEAERQKADKERLAAEL 1814 Query: 683 ENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHE 742 + + + E+L ++ E + E + +N L +LE+ + E+ L A++ Sbjct: 1815 DRAQEEAEKLAADLEKAEEEAERQKADNRRLAADNERLAAELER-AQEEAERLAAELERA 1873 Query: 743 EQSKIQTQFGIDAKIQERDLY---IENIESELSKYKS---RICRLEESIAVMEDR-RYSL 795 ++ + +D +E + +E E E + K+ R+ E +A DR + Sbjct: 1874 QEEAERLAAEVDRAQEEAEQLAADLEKAEEEAERQKADNRRLAADNERLAAELDRAQEEA 1933 Query: 796 ERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQ----------LLEIE 845 ER A +L +E ++ +E ++E A L + E+Q L + Sbjct: 1934 ERLAAELEKAEEEAERLAAELEKAQEEAERLAADLEKAEEDAERQKADNEQLAAELNRAQ 1993 Query: 846 HENKELQKKNQILLEENQNLQISLSDMQQHYNAL---VEKANR-TDLAESESTKYQTQLR 901 E K L + EE + L L Q+ L +EKA + ++++ + Sbjct: 1994 EEAKRLAADLERAQEEAEKLAAELERAQEEAEKLAADLEKAEEDAERQKADNERLAADNE 2053 Query: 902 DLESNLKRITHEHQTLIVQKKKEIEDLEIE------FNTQIESAIRDKKVLNEKYEKNIE 955 L + L+R E + L +K ED E + ++ A + K L E+ E Sbjct: 2054 RLAAELERTQEEAEKLAADLEKAEEDAERQKADNEQLAAELNRAQEEAKRLAADLERAQE 2113 Query: 956 YVTQLEAQLQEYKNNIENLNMNVE--ELNKMNLELIDKHVQKQQTQSPDYTEQYINEINK 1013 +L A+L+ + E L ++E E + + ++ + + E+ E K Sbjct: 2114 EAEKLAAELERAQEEAEKLAADLEKAEEDAERQKADNRRLAADNERLAAELERTQEEAEK 2173 Query: 1014 LNALLKQKDEEIIALNQKINNAQVSY-MSMVSDYESKLAQFTTKLENMEEEM----QRVS 1068 L A L++ +EE A QK +N +++ + + KLA K E E +R++ Sbjct: 2174 LAADLEKAEEE--AERQKADNERLAAELDRAQEEAEKLAADLEKAEEDAERQKADNERLA 2231 Query: 1069 KQLLDSKQHNEEL--QILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDAN 1126 +L +++ E+L + E+D + ++ +L E+N + E +++ +E ++A Sbjct: 2232 AELNRAQEEAEKLAADLEKAEEDAERQKADNERLAAELNRAQEEAERLAAELERAQEEAE 2291 Query: 1127 NVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKI----IQLETLN 1182 + K + E+ E + QE++ KL EL++ + LE Sbjct: 2292 KLAADLEKAEEEAERQKA-DNEQLAAELNRAQEEAEKLAAELEKAQEEAEKLAADLEKAE 2350 Query: 1183 TELTGHDVVNQE---QINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELW 1239 E N+ ++N+ + + E+L E + L + + A ++ AEL Sbjct: 2351 EEAERQKADNERLAAELNRAQEEAEKLAAELEKAQEEAERLAAELEKAQEEAERLAAELN 2410 Query: 1240 K-QHLAQR-EADFQKTEHE---LRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTS 1294 + Q A+R A+ ++ + E L +L + + E+L ++ + QEE ++ ++ Sbjct: 2411 RAQEEAERLAAELERAQEEAERLAAELDRAQEEAERLAAELERA-QEEAERLAA--ELNR 2467 Query: 1295 LQNKLQDKEEHLRNLQEKYADVINQIEILRSEIE---DEKVAFXXXXXXXXXXXXXXXXD 1351 Q + + +L QE+ E L +E+E +E + Sbjct: 2468 AQEEAEKLAANLEKAQEEAERQKAHNERLAAELERAREEAERLAAELEKAQEEAERLAAE 2527 Query: 1352 LRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLEL 1411 L + +++ + + EE +L ++ A+ + +L LE Sbjct: 2528 LEKAREEAERLAAE-LERAREEAERLAAELEKAQEEAERLAAELDRAQEEAEKLAADLEK 2586 Query: 1412 KDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENAN 1471 + E ++ + L D + ++L +R ++ +EL + + A Sbjct: 2587 AEEEAERQKADNE-RLAAELDRAQEEAERLAAELERAQEEAERLAAELDRAQEEAERLAA 2645 Query: 1472 HYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQE 1530 + Q+E+E L + + + AELN+A EE E++ A E E Sbjct: 2646 ELDRAQEEAEKLAADLEKAEEEAERQKADNERLAAELNRAQEEAERLAAELEKAQEEAE 2704 Score = 121 bits (291), Expect = 2e-25 Identities = 241/1373 (17%), Positives = 533/1373 (38%), Gaps = 78/1373 (5%) Query: 217 QMTKMQENFIAMEAEW---KDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSK 273 ++ + QE + AE ++E ++L D+E + + N+ L A E + Sbjct: 854 ELERAQEEAEKLAAELDRAQEEAEKLAADLEKAEEEAEKQKAHNERLAAELERAQEEAER 913 Query: 274 LAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEH 333 LA EL++ +++ E + + L EL + E E Sbjct: 914 LAAELDRALEEAEKLAADLEKAEEEAERQKAENRRLAADNERL----AAELDRAQEEAEK 969 Query: 334 LNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISR-KSGRNTASKMKSPWSQLSSE 392 L + + +E E + A + + ++ L + + A K+ + + + Sbjct: 970 LAADLEKAEEEAERQKAENRRLAAELERAQEEAERLAAELDRAQEEAEKLAADLEKAEEK 1029 Query: 393 TLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEK---DTXXXXXXXXXXGKDTLI 449 Q + + E+ + + + L +L D+ +EK D + Sbjct: 1030 AERQKAENRRLAAELERAQEEAERLAAEL-DRAQEEAEKLAADLEKAEEEAERQKAENRR 1088 Query: 450 AQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAE 509 +LE Q + E+ ++A E+ ++E E + + L +L+ A+ Sbjct: 1089 LAAELERAQEEAERLAAELDRAQEEAEKLAADLEKAEEEA--ERQKAENRRLAAELERAQ 1146 Query: 510 EQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNK----EIVRLTEELH 565 E+ +L E++ A + ++ + ++ +K + + + E+ R EE Sbjct: 1147 EEAERLAAELERAQEEAERLAAELDRAQEEAEKLAAELERAQEEAEKLAAELDRAQEEAE 1206 Query: 566 HLSQKVAELEEEKGNLQLHL-VDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKF 624 L+ ++ + +EE L L + + +++ K E E LA KA E QK Sbjct: 1207 RLAAELEKAQEEAERLAAELEKTQEEAERLAAELEKAQEEAERLAADLEKAEEDAERQKA 1266 Query: 625 DLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIEN 684 + + + + +E E AD+ + + D + + L +++ + LA +E Sbjct: 1267 EKERLAAEVDRAQEEAEKLAADLEKAEEDAERQKADNERLAAELNRAQEEAERLAADLEK 1326 Query: 685 LKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKM--SAEKISELLAKINHE 742 + D E+ + L D E + +L+ +E L +L++ AE+++ L K + Sbjct: 1327 AEEDAERQKADNRRLAADNERLAAELERAQEEAERLAAELDRAQEEAERLAADLEKAEED 1386 Query: 743 EQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLE---ESIAVMEDR-RYSLER- 797 + + + A++ E + ++L K + R + E +A +R L+R Sbjct: 1387 AERQKADNERLAAELDRAQEEAEKLAADLEKAEEDAERQKADNERLAADNERLAAELDRA 1446 Query: 798 --KADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKN 855 +A++L + L++ ++ + L L + + +L + + E + L + Sbjct: 1447 QEEAERLAADLEKAEEDAERQKADNERLAAELDRAQEEAERLAAELEKAQEEAERLAAEL 1506 Query: 856 QILLEENQNLQISLSDMQQHYNALVEKANR--TDL--AESESTKYQTQLRDLESNLKRIT 911 + EE + + + + E+A + DL AE ++ + + L + L R Sbjct: 1507 EKAQEEAERQKADKERLAAELDRAQEEAEKLAADLEKAEEDAERQKADNERLAAELNRAQ 1566 Query: 912 HEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNI 971 E + L +K ED E + D + L + E+ E +L A+L++ + Sbjct: 1567 EEAERLAADLEKAEEDAERQ-KADNRRLAADNERLAAELERAQEEAERLAAELEKAQEEA 1625 Query: 972 ENLNMNVEELNKMNLELIDKHVQK---QQTQSPDYTEQYINEINKLNALLKQKDEEIIAL 1028 E + E L L+ + +K ++ + E+ E +L A L++ EE L Sbjct: 1626 ERQKADKERL-AAELDRAQEEAEKLAADLEKAEEEAERQKAENRRLAAELERAQEEAERL 1684 Query: 1029 NQKINNAQVSYMSMVSDYE-SKLAQFTTKLEN--MEEEMQRVSKQLLDSKQHNEEL--QI 1083 +++ AQ + +D E ++ K +N + + +R++ +L +++ E L + Sbjct: 1685 AAELDRAQEEAEKLAADLEKAEEDAERQKADNRRLAADNERLAAELDRAQEEAERLAADL 1744 Query: 1084 LVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLK 1143 E+D + ++ +L E++ + E +++ +E ++A + K Sbjct: 1745 EKAEEDAERQKADNERLAAELDRAQEEAERLAAELEKAQEEAERLAAELEKAQEEAERQK 1804 Query: 1144 VQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKL 1203 ++E E QE++ KL +L++ + + + N L + ++ + + + Sbjct: 1805 A-DKERLAAELDRAQEEAEKLAADLEKAEEEAERQKADNRRLAADNERLAAELERAQEEA 1863 Query: 1204 EQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEH-------- 1255 E+L E + L + + A ++ A+L K A+ EA+ QK ++ Sbjct: 1864 ERLAAELERAQEEAERLAAEVDRAQEEAEQLAADLEK---AEEEAERQKADNRRLAADNE 1920 Query: 1256 ELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKL-------QDKEEHLRN 1308 L +L + + E+L ++ + +E +E+ +L ++ E + Sbjct: 1921 RLAAELDRAQEEAERLAAELEKAEEEAERLAAELEKAQEEAERLAADLEKAEEDAERQKA 1980 Query: 1309 LQEKYADVINQ---------IEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSY 1359 E+ A +N+ ++ R++ E EK+A + E+ Sbjct: 1981 DNEQLAAELNRAQEEAKRLAADLERAQEEAEKLAAELERAQEEAEKLAADLEKAEEDAER 2040 Query: 1360 KQMQEQSILNINEE-NAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQ 1418 ++ + + NE A+L+++ DAE + + QL + + + Sbjct: 2041 QKADNERLAADNERLAAELERTQEEAEKLAADLEKAEEDAERQKAD-NEQLAAELNRAQE 2099 Query: 1419 KTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKE-SELAILRLKMHENANHYETMQ 1477 + L + +E E + +L ++ E L + E +E R K + + Sbjct: 2100 EAKRLAADLERAQEEAEKLAAELERAQEEAEKLAADLEKAEEDAERQKADNRRLAADNER 2159 Query: 1478 KESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQE 1530 +E+ER + EE K+ + ++ AE KA E +A E+ A E E Sbjct: 2160 LAAELERTQ--EEAE-KLAADLEKAEEEAERQKADNERLAA--ELDRAQEEAE 2207 Score = 120 bits (290), Expect = 3e-25 Identities = 260/1375 (18%), Positives = 532/1375 (38%), Gaps = 89/1375 (6%) Query: 217 QMTKMQENFIAMEAEW---KDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSK 273 ++ + QE + AE ++E ++L D+E + + + N+ L A E + Sbjct: 994 ELERAQEEAERLAAELDRAQEEAEKLAADLEKAEEKAERQKAENRRLAAELERAQEEAER 1053 Query: 274 LAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEK---TEIEEKGSLEIANMTELTKKIEL 330 LA EL++ +++ E + E+E EL + E Sbjct: 1054 LAAELDRAQEEAEKLAADLEKAEEEAERQKAENRRLAAELERAQEEAERLAAELDRAQEE 1113 Query: 331 LEHLNCQIRQTNKELENKLA---TMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWS 387 E L + + +E E + A + E + +++ + + R + + Sbjct: 1114 AEKLAADLEKAEEEAERQKAENRRLAAELERAQEEAERLAAELERAQEEAERLAAELDRA 1173 Query: 388 QLSSETLNQDTDKKINKNE--IAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGK 445 Q +E L + ++ + E A+L+ + + + E E + Sbjct: 1174 QEEAEKLAAELERAQEEAEKLAAELDRAQEEAERLAAELEKAQEEAERLAAELEKTQEEA 1233 Query: 446 DTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEI--KDVNVKDLIE 503 + L A+L+ + Q+ E + + E E A+ Q+ K+ L E+ + L Sbjct: 1234 ERLAAELE-KAQEEAE-----RLAADLEKAEEDAERQKAEKERLAAEVDRAQEEAEKLAA 1287 Query: 504 KLKSAEEQI-------TQLNDEIDAANKNMIKVKSN-HKLKLKQMQKTIDNFSKVSDSNK 555 L+ AEE +L E++ A + ++ ++ K + ++ DN +D+ + Sbjct: 1288 DLEKAEEDAERQKADNERLAAELNRAQEEAERLAADLEKAEEDAERQKADNRRLAADNER 1347 Query: 556 ---EIVRLTEELHHLSQKVAELEEEKGNL--QLHLVDYDSGRM------IESDVYKKMIE 604 E+ R EE L+ ++ +EE L L + D+ R + +++ + E Sbjct: 1348 LAAELERAQEEAERLAAELDRAQEEAERLAADLEKAEEDAERQKADNERLAAELDRAQEE 1407 Query: 605 MENLAETRLKAISLLESQKFD---LVQELHILQQKYD----EVEDKLADISQLQSDQVCS 657 E LA KA E QK D L + L + D E E AD+ + + D Sbjct: 1408 AEKLAADLEKAEEDAERQKADNERLAADNERLAAELDRAQEEAERLAADLEKAEEDAERQ 1467 Query: 658 EIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQEN 717 + + L ++D + LA +E + + E+L ++ + + E + E Sbjct: 1468 KADNERLAAELDRAQEEAERLAAELEKAQEEAERLAAELEKAQEEAERQKADKERLAAEL 1527 Query: 718 MDLTDKLEKMSAE-KISELLAKINHEEQSKIQTQFGIDAKIQER-DLYIENIESELSKYK 775 ++ EK++A+ + +E A+ + ++ + + ER +E E + + K Sbjct: 1528 DRAQEEAEKLAADLEKAEEDAERQKADNERLAAELNRAQEEAERLAADLEKAEEDAERQK 1587 Query: 776 SRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDH-D 834 + RL A E LER ++ E +KA E Q+ + RLA +D Sbjct: 1588 ADNRRL---AADNERLAAELERAQEEAERLAAELEKAQEEAERQKAD-KERLAAELDRAQ 1643 Query: 835 RVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESEST 894 EK ++E +E +++ EN+ L L Q+ L A D A+ E+ Sbjct: 1644 EEAEKLAADLEKAEEEAERQK----AENRRLAAELERAQEEAERL---AAELDRAQEEAE 1696 Query: 895 KYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNI 954 K L E + +R +++ L ++ +L+ + E D + E E+ Sbjct: 1697 KLAADLEKAEEDAERQKADNRRLAADNERLAAELD-RAQEEAERLAADLEKAEEDAERQK 1755 Query: 955 EYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKL 1014 +L A+L + E L +E+ + E + ++K Q ++ E+ + +L Sbjct: 1756 ADNERLAAELDRAQEEAERLAAELEKAQE-EAERLAAELEKAQEEA----ERQKADKERL 1810 Query: 1015 NALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLA---QFTTKLENMEEEMQRVSKQL 1071 A L + EE L + A+ +D A + +LE +EE +R++ +L Sbjct: 1811 AAELDRAQEEAEKLAADLEKAEEEAERQKADNRRLAADNERLAAELERAQEEAERLAAEL 1870 Query: 1072 LDSKQHNEELQILVREQDDQIKELKE--TKLTFEMNIPKTEGMIISSTIEPMSDDANNVD 1129 +++ E L V ++ ++L K E K + +++ E ++ + + Sbjct: 1871 ERAQEEAERLAAEVDRAQEEAEQLAADLEKAEEEAERQKADNRRLAADNERLAAELDRAQ 1930 Query: 1130 XXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHD 1189 + +E E E QE++ +L +L++ + + N +L Sbjct: 1931 EEAERLAAELEKAE-EEAERLAAELEKAQEEAERLAADLEKAEEDAERQKADNEQLAAEL 1989 Query: 1190 VVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISS-AVD-QRGFEIAELWKQHLAQRE 1247 QE+ +L + LE+ E + L + + + A D ++ E AE K + Sbjct: 1990 NRAQEEAKRLAADLERAQEEAEKLAAELERAQEEAEKLAADLEKAEEDAERQKADNERLA 2049 Query: 1248 ADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLR 1307 AD ++ L +L + + E+L ++ + ++ + EQ+ + N+ Q++ + L Sbjct: 2050 ADNER----LAAELERTQEEAEKLAADLEKAEEDAERQKADNEQLAAELNRAQEEAKRLA 2105 Query: 1308 NLQEKYADVINQI--EILRSEIEDEKVAF-XXXXXXXXXXXXXXXXDLRTENQSYKQMQE 1364 E+ + ++ E+ R++ E EK+A L +N+ E Sbjct: 2106 ADLERAQEEAEKLAAELERAQEEAEKLAADLEKAEEDAERQKADNRRLAADNERLAAELE 2165 Query: 1365 QSILNINEENAQLKKS---SXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTH 1421 ++ + A L+K+ + ++ A+ + +L LE + + ++ Sbjct: 2166 RTQEEAEKLAADLEKAEEEAERQKADNERLAAELDRAQEEAEKLAADLEKAEEDAERQKA 2225 Query: 1422 EYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEK--ESELAILRLKMHENANHYETMQKE 1479 + + N E + + EK ED +K LA + E A + Sbjct: 2226 DNERLAAELNRAQEEAEKLAADLEKAEEDAERQKADNERLAAELNRAQEEAERLAAELER 2285 Query: 1480 SEIERVKL---IEELNVKITESVSLNKQV-AELNKALEEEVAKTNEMQTALENQE 1530 ++ E KL +E+ + + N+Q+ AELN+A EE E++ A E E Sbjct: 2286 AQEEAEKLAADLEKAEEEAERQKADNEQLAAELNRAQEEAEKLAAELEKAQEEAE 2340 Score = 116 bits (279), Expect = 5e-24 Identities = 258/1377 (18%), Positives = 528/1377 (38%), Gaps = 84/1377 (6%) Query: 233 KDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXX 292 ++E ++L D+E + + N+ L A E +LA EL++ Sbjct: 964 QEEAEKLAADLEKAEEEAERQKAENRRLAAELERAQEEAERLAAELDRAQEEAEKLAADL 1023 Query: 293 XXLAKQSIEPSCEEK---TEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKL 349 +++ E + E+E EL + E E L + + +E E + Sbjct: 1024 EKAEEKAERQKAENRRLAAELERAQEEAERLAAELDRAQEEAEKLAADLEKAEEEAERQK 1083 Query: 350 ATMGTESKAVSSPSKKGSPLISR-KSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIA 408 A + + ++ L + + A K+ + + E Q K N+ A Sbjct: 1084 AENRRLAAELERAQEEAERLAAELDRAQEEAEKLAADLEKAEEEAERQ---KAENRRLAA 1140 Query: 409 KLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQ-LEHQQHMEGPSLIH 467 +LE + + + E E + + L A+L+ + + L Sbjct: 1141 ELERAQEEAERLAAELERAQEEAERLAAELDRAQEEAEKLAAELERAQEEAEKLAAELDR 1200 Query: 468 VGTNTEDV-NEIAKVQEQLKQELND-EIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKN 525 E + E+ K QE+ ++ + E + L +L+ A+E+ +L +++ A ++ Sbjct: 1201 AQEEAERLAAELEKAQEEAERLAAELEKTQEEAERLAAELEKAQEEAERLAADLEKAEED 1260 Query: 526 MIKVKSNHKLKLKQMQKTIDNFSKV-SDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLH 584 + K+ + ++ + + K+ +D K + + AEL + + Sbjct: 1261 AERQKAEKERLAAEVDRAQEEAEKLAADLEKAEEDAERQKADNERLAAELNRAQEEAERL 1320 Query: 585 LVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKL 644 D + E D ++ + LA + + LE + + + L + +E E Sbjct: 1321 AADLEKA---EEDAERQKADNRRLAADNERLAAELERAQEEAERLAAELDRAQEEAERLA 1377 Query: 645 ADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKE 704 AD+ + + D + + L ++D ++LA +E + D E+ + L D E Sbjct: 1378 ADLEKAEEDAERQKADNERLAAELDRAQEEAEKLAADLEKAEEDAERQKADNERLAADNE 1437 Query: 705 DIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYI 764 + +L +E L LEK AE+ +E K ++E + +D +E + Sbjct: 1438 RLAAELDRAQEEAERLAADLEK--AEEDAE-RQKADNERLAA-----ELDRAQEEAERLA 1489 Query: 765 ENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELV 824 +E + + LE++ E ++ ER A +L +E +K ++ E++ Sbjct: 1490 AELEKAQEEAERLAAELEKAQEEAERQKADKERLAAELDRAQEEAEKLAADLEKAEEDAE 1549 Query: 825 NRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKAN 884 + A D++R+ E+ +E ++ L + ++ + +D ++ A Sbjct: 1550 RQKA---DNERLA----AELNRAQEEAERLAADLEKAEEDAERQKADNRRLAADNERLAA 1602 Query: 885 RTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKK 944 + A+ E+ + +L + +R + + L + + E+ E + +E A +++ Sbjct: 1603 ELERAQEEAERLAAELEKAQEEAERQKADKERLAAELDRAQEEAE-KLAADLEKA--EEE 1659 Query: 945 VLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYT 1004 +K E N +LE +E + L+ EE K+ +L +K + + Q D Sbjct: 1660 AERQKAE-NRRLAAELERAQEEAERLAAELDRAQEEAEKLAADL-EKAEEDAERQKAD-N 1716 Query: 1005 EQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEM 1064 + + +L A L + EE L + A+ +D E + +L+ +EE Sbjct: 1717 RRLAADNERLAAELDRAQEEAERLAADLEKAEEDAERQKADNE----RLAAELDRAQEEA 1772 Query: 1065 QRVSKQLLDSKQHNEELQILVREQDDQIKELKETK--LTFEMNIPKTEGMIISSTIEPMS 1122 +R++ +L +++ E L + + ++ + K K L E++ + E +++ +E Sbjct: 1773 ERLAAELEKAQEEAERLAAELEKAQEEAERQKADKERLAAELDRAQEEAEKLAADLEKAE 1832 Query: 1123 DDANNVDXXXXXXXXXXXXL-----KVQEE-EEFIQERSVLQEQSAKLNTELQECYTKII 1176 ++A L + QEE E E QE++ +L E+ + Sbjct: 1833 EEAERQKADNRRLAADNERLAAELERAQEEAERLAAELERAQEEAERLAAEVDRAQEEAE 1892 Query: 1177 QLETLNTELTGHDVVNQEQIN-QLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEI 1235 QL + E + Q+ N +L + E+L E D L + + A ++ Sbjct: 1893 QL-AADLEKAEEEAERQKADNRRLAADNERLAAELDRAQEEAERLAAELEKAEEEAERLA 1951 Query: 1236 AELWK-QHLAQR-EADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVT 1293 AEL K Q A+R AD +K E + Q ++ EQL + + +E +E+ Sbjct: 1952 AELEKAQEEAERLAADLEKAEEDAERQ----KADNEQLAAELNRAQEEAKRLAADLERAQ 2007 Query: 1294 SLQNKLQDKEEHLRNLQEKYADVINQIE--ILRSEIEDEKVAFXXXXXXXXXXXXXXXXD 1351 KL + E + EK A + + E R + ++E++A Sbjct: 2008 EEAEKLAAELERAQEEAEKLAADLEKAEEDAERQKADNERLAADNERLAAELE------- 2060 Query: 1352 LRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLEL 1411 RT+ ++ K + L EE+A+ +K+ +N A+ + L LE Sbjct: 2061 -RTQEEAEKLAAD---LEKAEEDAERQKAD------NEQLAAELNRAQEEAKRLAADLER 2110 Query: 1412 KDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENAN 1471 E + E L + +E E + L EK ED +K ++ L A Sbjct: 2111 AQEEAEKLAAE----LERAQEEAEKLAADL---EKAEEDAERQK-ADNRRLAADNERLAA 2162 Query: 1472 HYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEI 1531 E Q+E+E L + + + AEL++A EE +++ A E+ E Sbjct: 2163 ELERTQEEAEKLAADLEKAEEEAERQKADNERLAAELDRAQEEAEKLAADLEKAEEDAER 2222 Query: 1532 EIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAE 1588 + N+ + N + + K+ + A + + R + + + EL A AE Sbjct: 2223 QKAD-NERLAAELNRAQEEAEKLAADLEKAEEDAE-RQKADNERLAAELNRAQEEAE 2277 Score = 112 bits (270), Expect = 7e-23 Identities = 257/1374 (18%), Positives = 542/1374 (39%), Gaps = 105/1374 (7%) Query: 233 KDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXX 292 K + +RL D E + +E + L A E KLA +LE+ Sbjct: 838 KADNRRLAADNERLAAELERAQEEAEKLAAELDRAQEEAEKLAADLEKAEEEAEKQKAHN 897 Query: 293 XXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATM 352 LA + +E + EE + EL + +E E L + + +E E + A Sbjct: 898 ERLAAE-LERAQEEAERL----------AAELDRALEEAEKLAADLEKAEEEAERQKA-- 944 Query: 353 GTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEM 412 E++ +++ +++ + + R + A K+ + + E Q + + E+ + + Sbjct: 945 --ENRRLAADNERLAAELDR--AQEEAEKLAADLEKAEEEAERQKAENRRLAAELERAQE 1000 Query: 413 VIQSLNKDLVDKEYVISEK---DTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVG 469 + L +L D+ +EK D + +LE Q + Sbjct: 1001 EAERLAAEL-DRAQEEAEKLAADLEKAEEKAERQKAENRRLAAELERAQEEAERLAAELD 1059 Query: 470 TNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKV 529 E+ ++A E+ ++E E + + L +L+ A+E+ +L E+D A + K+ Sbjct: 1060 RAQEEAEKLAADLEKAEEEA--ERQKAENRRLAAELERAQEEAERLAAELDRAQEEAEKL 1117 Query: 530 KSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYD 589 ++ + ++ ++ +++ E+ R EE L+ ++ +EE L L Sbjct: 1118 AADLEKAEEEAERQKAENRRLA---AELERAQEEAERLAAELERAQEEAERLAAEL---- 1170 Query: 590 SGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADI-- 647 + + K E+E E K + L+ + + + L++ +E E A++ Sbjct: 1171 --DRAQEEAEKLAAELERAQEEAEKLAAELDRAQEEAERLAAELEKAQEEAERLAAELEK 1228 Query: 648 SQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIM 707 +Q +++++ +E++ +E+ + L+A ++ E K +KE+L + + + E + Sbjct: 1229 TQEEAERLAAELEKA--QEEAERLAADLEKAEEDAERQKAEKERLAAEVDRAQEEAEKLA 1286 Query: 708 NKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENI 767 L+ + E+ A+ L A++N ++ + D + E D + Sbjct: 1287 ADLEK-------AEEDAERQKADN-ERLAAELNRAQEE--AERLAADLEKAEEDAERQKA 1336 Query: 768 ES-ELSKYKSRI-CRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVN 825 ++ L+ R+ LE + E L+R ++ + +KA + Q+ + Sbjct: 1337 DNRRLAADNERLAAELERAQEEAERLAAELDRAQEEAERLAADLEKAEEDAERQKAD-NE 1395 Query: 826 RLAVLMDHDRVVEKQL---LEIEHENKELQK-KNQILLEENQNLQISLSDMQQHYNALVE 881 RLA +D + ++L LE E+ E QK N+ L +N+ L L Q+ L Sbjct: 1396 RLAAELDRAQEEAEKLAADLEKAEEDAERQKADNERLAADNERLAAELDRAQEEAERL-- 1453 Query: 882 KANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKK---EIEDLEIEFNTQIES 938 A + AE ++ + + L + L R E + L + +K E E L E E Sbjct: 1454 -AADLEKAEEDAERQKADNERLAAELDRAQEEAERLAAELEKAQEEAERLAAELEKAQEE 1512 Query: 939 AIR---DKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVE----ELNKMNLEL--- 988 A R DK+ L + ++ E +L A L++ + + E + E ELN+ E Sbjct: 1513 AERQKADKERLAAELDRAQEEAEKLAADLEKAEEDAERQKADNERLAAELNRAQEEAERL 1572 Query: 989 ---IDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSD 1045 ++K + + Q D + + +L A L++ EE L ++ AQ +D Sbjct: 1573 AADLEKAEEDAERQKAD-NRRLAADNERLAAELERAQEEAERLAAELEKAQEEAERQKAD 1631 Query: 1046 YESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKE--TKLTFE 1103 E + +L+ +EE ++++ L +++ E + R +++ +E +L E Sbjct: 1632 KE----RLAAELDRAQEEAEKLAADLEKAEEEAERQKAENRRLAAELERAQEEAERLAAE 1687 Query: 1104 MNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAK 1163 ++ + E +++ +E +DA + E E QE++ + Sbjct: 1688 LDRAQEEAEKLAADLEKAEEDAERQKADNRRLAA--------DNERLAAELDRAQEEAER 1739 Query: 1164 LNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSS 1223 L +L++ + + N L QE+ +L ++LE+ E + L + + + + Sbjct: 1740 LAADLEKAEEDAERQKADNERLAAELDRAQEEAERLAAELEKAQEEAERLAAELEKAQEE 1799 Query: 1224 ISSAVDQRGFEIAELWK-QHLAQR-EADFQKTEHELRVQLS---AFESKYEQLLDSVQSS 1278 + AEL + Q A++ AD +K E E Q + + E+L ++ + Sbjct: 1800 AERQKADKERLAAELDRAQEEAEKLAADLEKAEEEAERQKADNRRLAADNERLAAELERA 1859 Query: 1279 TQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXX 1338 QEE ++ ++ Q + + + QE+ + +E E E +K A Sbjct: 1860 -QEEAERLAA--ELERAQEEAERLAAEVDRAQEEAEQLAADLEKAEEEAERQK-ADNRRL 1915 Query: 1339 XXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDA 1398 + E + E++ A+L+K+ DA Sbjct: 1916 AADNERLAAELDRAQEEAERLAAELEKAEEEAERLAAELEKAQEEAERLAADLEKAEEDA 1975 Query: 1399 EAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKE-S 1457 E + + QL + + ++ L + +E E + +L ++ E L + E + Sbjct: 1976 ERQKAD-NEQLAAELNRAQEEAKRLAADLERAQEEAEKLAAELERAQEEAEKLAADLEKA 2034 Query: 1458 ELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEV- 1516 E R K + + +E+ER + EE K+ + ++ AE KA E++ Sbjct: 2035 EEDAERQKADNERLAADNERLAAELERTQ--EEAE-KLAADLEKAEEDAERQKADNEQLA 2091 Query: 1517 AKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDE 1570 A+ N Q + ++ +E L + + + +K A+D ++ ++ Sbjct: 2092 AELNRAQEEAKRLAADLERAQEEAEKLAAELERAQEEAEK---LAADLEKAEED 2142 Score = 105 bits (251), Expect = 1e-20 Identities = 213/1157 (18%), Positives = 471/1157 (40%), Gaps = 84/1157 (7%) Query: 469 GTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIK 528 GT + E + E+ K + N + N + L +L+ A+E+ +L E+D A + K Sbjct: 821 GTLARQLQEAQQDAERQKAD-NRRLAADNER-LAAELERAQEEAEKLAAELDRAQEEAEK 878 Query: 529 VKSNHKLKLKQMQKTIDN----FSKVSDSNKEIVRLTEELHHLSQKV---------AELE 575 + ++ + ++ +K + +++ + +E RL EL ++ AE E Sbjct: 879 LAADLEKAEEEAEKQKAHNERLAAELERAQEEAERLAAELDRALEEAEKLAADLEKAEEE 938 Query: 576 EEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFD---LVQELHI 632 E+ + + D+ R + +++ + E E LA KA E QK + L EL Sbjct: 939 AERQKAENRRLAADNER-LAAELDRAQEEAEKLAADLEKAEEEAERQKAENRRLAAELER 997 Query: 633 LQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQL 692 Q++ + + +L D +Q +++++ ++++ EE+ + A + LA +E + + E+L Sbjct: 998 AQEEAERLAAEL-DRAQEEAEKLAADLEKA--EEKAERQKAENRRLAAELERAQEEAERL 1054 Query: 693 YGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFG 752 + + + E + L+ +E E+ AE L A++ ++ + Sbjct: 1055 AAELDRAQEEAEKLAADLEKAEEE-------AERQKAEN-RRLAAELERAQEEAERLAAE 1106 Query: 753 IDAKIQERDLY---IENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEK 809 +D +E + +E E E + K+ RL A +E + ER A +L +E Sbjct: 1107 LDRAQEEAEKLAADLEKAEEEAERQKAENRRL---AAELERAQEEAERLAAELERAQEEA 1163 Query: 810 QKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISL 869 ++ +E ++E A L EK E++ +E ++ L + + + Sbjct: 1164 ERLAAELDRAQEEAEKLAAELERAQEEAEKLAAELDRAQEEAERLAAELEKAQEEAERLA 1223 Query: 870 SDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLE 929 +++++ A + A+ E+ + L E + +R E + L + + E+ E Sbjct: 1224 AELEKTQEEAERLAAELEKAQEEAERLAADLEKAEEDAERQKAEKERLAAEVDRAQEEAE 1283 Query: 930 IEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELI 989 + +E A D + +K + N +L +E + +L E+ + + Sbjct: 1284 -KLAADLEKAEEDAE--RQKAD-NERLAAELNRAQEEAERLAADLEKAEEDAERQKAD-- 1337 Query: 990 DKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESK 1049 ++ + + E+ E +L A L + EE L + A+ +D E Sbjct: 1338 NRRLAADNERLAAELERAQEEAERLAAELDRAQEEAERLAADLEKAEEDAERQKADNE-- 1395 Query: 1050 LAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKT 1109 + +L+ +EE ++++ L +++ E ++ D++ +L E++ + Sbjct: 1396 --RLAAELDRAQEEAEKLAADLEKAEEDAER-----QKADNERLAADNERLAAELDRAQE 1448 Query: 1110 EGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQ 1169 E +++ +E +DA + +E E E QE++ +L EL+ Sbjct: 1449 EAERLAADLEKAEEDAERQKADNERLAAELDRAQ-EEAERLAAELEKAQEEAERLAAELE 1507 Query: 1170 ECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVD 1229 + + + + L QE+ +L + LE+ + + + L + ++ A + Sbjct: 1508 KAQEEAERQKADKERLAAELDRAQEEAEKLAADLEKAEEDAERQKADNERLAAELNRAQE 1567 Query: 1230 QRGFEIAELWKQHLAQREADFQKTEH--------ELRVQLSAFESKYEQLLDSVQSSTQE 1281 + A+L K A+ +A+ QK ++ L +L + + E+L ++ + +E Sbjct: 1568 EAERLAADLEK---AEEDAERQKADNRRLAADNERLAAELERAQEEAERLAAELEKAQEE 1624 Query: 1282 ETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXX 1341 + E++ + ++ Q++ E L EK + E R + E+ ++A Sbjct: 1625 AERQKADKERLAAELDRAQEEAEKLAADLEKAEE-----EAERQKAENRRLAAELERAQE 1679 Query: 1342 XXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKS-SXXXXXXXXXXXXRVNDAEA 1400 D R + ++ K + L EE+A+ +K+ + ++ A+ Sbjct: 1680 EAERLAAELD-RAQEEAEKLAAD---LEKAEEDAERQKADNRRLAADNERLAAELDRAQE 1735 Query: 1401 KVLELTHQLEL--KDSEIYQKTHE-YTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKE- 1456 + L LE +D+E + +E L + +E E + +L + ++ E L E E Sbjct: 1736 EAERLAADLEKAEEDAERQKADNERLAAELDRAQEEAERLAAELEKAQEEAERLAAELEK 1795 Query: 1457 SELAILRLKMHENANHYETMQKESEIERVKL-IEELNVKITESVSLNKQVAELNKALEEE 1515 ++ R K + E + + E E++ +E+ + + N+++A N+ L E Sbjct: 1796 AQEEAERQKADKERLAAELDRAQEEAEKLAADLEKAEEEAERQKADNRRLAADNERLAAE 1855 Query: 1516 VAKTNE----MQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQ 1571 + + E + LE + E L E+ Q ++ ++K A +Q D + Sbjct: 1856 LERAQEEAERLAAELERAQEEAERLAAEVDRAQEEAEQLAADLEKAEEEAE--RQKADNR 1913 Query: 1572 LDNTMNKELLDAVPRAE 1588 N+ L + RA+ Sbjct: 1914 RLAADNERLAAELDRAQ 1930 Score = 97.5 bits (232), Expect = 3e-18 Identities = 195/1033 (18%), Positives = 404/1033 (39%), Gaps = 75/1033 (7%) Query: 564 LHHLSQKVAELEEEKGNLQLHLVDYDS-GRMIESDVYKKMIEMENLAETRLKAISLLESQ 622 LHH ++ L + Q + R + +D + E+E E K + L+ Sbjct: 813 LHHAEEEAGTLARQLQEAQQDAERQKADNRRLAADNERLAAELERAQEEAEKLAAELDRA 872 Query: 623 KFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVI 682 + + + L++ +E E + A +L ++ ++ ++ L ++D ++LA + Sbjct: 873 QEEAEKLAADLEKAEEEAEKQKAHNERLAAELERAQEEAERLAAELDRALEEAEKLAADL 932 Query: 683 ENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAE------KISELL 736 E + + E+ + L D E + +L +E L LEK E + L Sbjct: 933 EKAEEEAERQKAENRRLAADNERLAAELDRAQEEAEKLAADLEKAEEEAERQKAENRRLA 992 Query: 737 AKINHEEQSKIQTQFGIDAKIQERDLYIENIE-----SELSKYKSRICRLEESIAVMEDR 791 A++ ++ + +D +E + ++E +E K ++R E A E Sbjct: 993 AELERAQEEAERLAAELDRAQEEAEKLAADLEKAEEKAERQKAENRRLAAELERAQEEAE 1052 Query: 792 RYSLE-----RKADQLGSYLQ------EKQKAYSEYTIQE----DELVNRLAVLMDH-DR 835 R + E +A++L + L+ E+QKA + E E RLA +D Sbjct: 1053 RLAAELDRAQEEAEKLAADLEKAEEEAERQKAENRRLAAELERAQEEAERLAAELDRAQE 1112 Query: 836 VVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRT-DLAE---S 891 EK ++E +E +++ EN+ L L Q+ L + R + AE + Sbjct: 1113 EAEKLAADLEKAEEEAERQK----AENRRLAAELERAQEEAERLAAELERAQEEAERLAA 1168 Query: 892 ESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYE 951 E + Q + L + L+R E + L + + E+ E ++E A + + L + E Sbjct: 1169 ELDRAQEEAEKLAAELERAQEEAEKLAAELDRAQEEAE-RLAAELEKAQEEAERLAAELE 1227 Query: 952 KNIEYVTQLEAQLQEYKNNIENLNMNVE------ELNKMNLELIDKHVQKQQTQ------ 999 K E +L A+L++ + E L ++E E K E + V + Q + Sbjct: 1228 KTQEEAERLAAELEKAQEEAERLAADLEKAEEDAERQKAEKERLAAEVDRAQEEAEKLAA 1287 Query: 1000 ----SPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLA---Q 1052 + + E+ + +L A L + EE L + A+ +D A + Sbjct: 1288 DLEKAEEDAERQKADNERLAAELNRAQEEAERLAADLEKAEEDAERQKADNRRLAADNER 1347 Query: 1053 FTTKLENMEEEMQRVSKQLLDSKQHNEEL--QILVREQDDQIKELKETKLTFEMNIPKTE 1110 +LE +EE +R++ +L +++ E L + E+D + ++ +L E++ + E Sbjct: 1348 LAAELERAQEEAERLAAELDRAQEEAERLAADLEKAEEDAERQKADNERLAAELDRAQEE 1407 Query: 1111 GMIISSTIEPMSDDANNVDXXXXXXXXXXXXL-----KVQEE-EEFIQERSVLQEQSAKL 1164 +++ +E +DA L + QEE E + +E + + Sbjct: 1408 AEKLAADLEKAEEDAERQKADNERLAADNERLAAELDRAQEEAERLAADLEKAEEDAERQ 1467 Query: 1165 NTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSI 1224 + + ++ + + L QE+ +L ++LE+ E + + L + + Sbjct: 1468 KADNERLAAELDRAQEEAERLAAELEKAQEEAERLAAELEKAQEEAERQKADKERLAAEL 1527 Query: 1225 SSAVDQRGFEIAELWKQHLAQREADFQKTEHE-LRVQLSAFESKYEQLLDSVQSSTQEET 1283 A ++ A+L K A+ +A+ QK ++E L +L+ + + E+L ++ + ++ Sbjct: 1528 DRAQEEAEKLAADLEK---AEEDAERQKADNERLAAELNRAQEEAERLAADLEKAEEDAE 1584 Query: 1284 NKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVIN--QIEILRSEIEDEKVAFXXXXXXX 1341 + ++ + +L + E + E+ A + Q E R + + E++A Sbjct: 1585 RQKADNRRLAADNERLAAELERAQEEAERLAAELEKAQEEAERQKADKERLAAELDRAQE 1644 Query: 1342 XXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAK 1401 + + E ++ +Q E L E AQ + A+ + Sbjct: 1645 EAEKLAADLE-KAEEEAERQKAENRRLAAELERAQEEAERLAAELDRAQEEAEKLAADLE 1703 Query: 1402 VLELTHQLELKDSEIYQKTHE-YTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKE---S 1457 E + + D+ +E L + +E E + L + E+ E + E + Sbjct: 1704 KAEEDAERQKADNRRLAADNERLAAELDRAQEEAERLAADLEKAEEDAERQKADNERLAA 1763 Query: 1458 ELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVA 1517 EL + + A E Q+E+E +L + + + AEL++A EE Sbjct: 1764 ELDRAQEEAERLAAELEKAQEEAERLAAELEKAQEEAERQKADKERLAAELDRAQEEAEK 1823 Query: 1518 KTNEMQTALENQE 1530 +++ A E E Sbjct: 1824 LAADLEKAEEEAE 1836 Score = 84.2 bits (199), Expect = 3e-14 Identities = 196/1090 (17%), Positives = 422/1090 (38%), Gaps = 62/1090 (5%) Query: 53 KFERAQKCLENAALVSKRIKEHRKATAELLGRPFVPGISESLANTLKQKEILMEKIKQYK 112 + ERAQ+ E A +R +E + A + R +E LA L++ E E+ ++ K Sbjct: 1855 ELERAQEEAERLAAELERAQEEAERLAAEVDR--AQEEAEQLAADLEKAE---EEAERQK 1909 Query: 113 ELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNALSVLQVKMKIMETTI 172 ++R + R L +E + + L+ + E Sbjct: 1910 ADNRRLAADNERLAAELDRAQEEAERL----AAELEKAEEEAERLAAELEKAQEEAERLA 1965 Query: 173 LDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEW 232 DL EK E + +A N+ E +++ K+ A E E Sbjct: 1966 ADL-EKAEEDAERQKADNEQLAAELNRAQEEAKRLAADLERAQEEAEKL-----AAELER 2019 Query: 233 -KDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXX 291 ++E ++L D+E + + N+ L A ++ E + +E E+ Sbjct: 2020 AQEEAEKLAADLEKAEEDAERQKADNERLAADNERLAAELERTQEEAEKLAADLEKAEED 2079 Query: 292 XXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLAT 351 + + + E EE L +L + E E L ++ + +E E KLA Sbjct: 2080 AERQKADNEQLAAELNRAQEEAKRLA----ADLERAQEEAEKLAAELERAQEEAE-KLAA 2134 Query: 352 MGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKL- 410 +++ + K + ++ + R A ++ Q +E L D +K + E K Sbjct: 2135 DLEKAEEDAERQKADNRRLAADNERLAAELERT---QEEAEKLAADLEKAEEEAERQKAD 2191 Query: 411 -EMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVG 469 E + L++ + E + ++ + + L A+L ++ + + + Sbjct: 2192 NERLAAELDRAQEEAEKLAADLEKAEEDAERQKADNERLAAELNRAQEEAEKLAADLEKA 2251 Query: 470 TNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKV 529 ED E+L ELN ++ + L +L+ A+E+ +L +++ A + + Sbjct: 2252 E--EDAERQKADNERLAAELNRAQEEA--ERLAAELERAQEEAEKLAADLEKAEEEAERQ 2307 Query: 530 KSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYD 589 K++++ ++ + + K++ E+ + EE L+ + + EEE + D Sbjct: 2308 KADNEQLAAELNRAQEEAEKLA---AELEKAQEEAEKLAADLEKAEEEAERQKA-----D 2359 Query: 590 SGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQ 649 + R+ +++ + E E LA KA E +L + ++ E+ + + Sbjct: 2360 NERLA-AELNRAQEEAEKLAAELEKAQEEAERLAAELEKAQEEAERLAAELNRAQEEAER 2418 Query: 650 LQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNK 709 L ++ ++ ++ L ++D + LA +E + + E+L + + + E + Sbjct: 2419 LAAELERAQEEAERLAAELDRAQEEAERLAAELERAQEEAERLAAELNRAQEEAEKLAAN 2478 Query: 710 LQNYIQENMDLTDKLEKMSAE--KISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENI 767 L+ +E E+++AE + E ++ E + + + A++++ E + Sbjct: 2479 LEKAQEEAERQKAHNERLAAELERAREEAERLAAELEKAQEEAERLAAELEKAREEAERL 2538 Query: 768 ESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVN-- 825 +EL + + RL A +E + ER A +L +E +K ++ E+E Sbjct: 2539 AAELERAREEAERLA---AELEKAQEEAERLAAELDRAQEEAEKLAADLEKAEEEAERQK 2595 Query: 826 ----RLAVLMDH-DRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALV 880 RLA +D E+ E+E +E ++ L + + +++ + Sbjct: 2596 ADNERLAAELDRAQEEAERLAAELERAQEEAERLAAELDRAQEEAERLAAELDRAQEEAE 2655 Query: 881 EKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKK---EIEDLEIEFNTQIE 937 + A + AE E+ + + L + L R E + L + +K E E L + E Sbjct: 2656 KLAADLEKAEEEAERQKADNERLAAELNRAQEEAERLAAELEKAQEEAEKLAADLEKAEE 2715 Query: 938 SAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQ 997 A R K N +L+ +E + L+ EE ++ EL D+ ++ + Sbjct: 2716 DAERQKADNRRLAADNERLAAELDRAQEEAERLAAELDRAQEEAERLAAEL-DRAQEEAE 2774 Query: 998 TQSPDY--TEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTT 1055 + D E+ N L +E + A + + + + + + Sbjct: 2775 KLAADLEKAEEDAERQKADNRRLAADNERLAAELDRAQEEAERLAAELDRAQEEAEKLAA 2834 Query: 1056 KLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIIS 1115 LE EE+ +R Q D+++ + + L E D +E + +L E++ + E ++ Sbjct: 2835 DLEKAEEDAER---QKADNRRLAADNERLAAELDRAQEEAE--RLAAELDRAQEEAERLA 2889 Query: 1116 STIEPMSDDA 1125 + ++ +DA Sbjct: 2890 AELDRAQEDA 2899 Score = 36.7 bits (81), Expect = 5.3 Identities = 92/550 (16%), Positives = 203/550 (36%), Gaps = 33/550 (6%) Query: 53 KFERAQKCLENAALVSKRIKEHRKATAELLGRPFVPGISESLANTLKQKEILMEKIKQYK 112 + RAQ+ E A +R +E + A L R +E LA L++ + E++ Sbjct: 2408 ELNRAQEEAERLAAELERAQEEAERLAAELDR--AQEEAERLAAELERAQEEAERLAAEL 2465 Query: 113 ELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNALSVLQVKMKIMETTI 172 ++ + + L +E + + L+ + E Sbjct: 2466 NRAQEEAEKLAANLEKAQEEAERQKAHNERLAAELERAREEAERLAAELEKAQEEAERLA 2525 Query: 173 LDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEW 232 +L EK E+ + + A+ + E ++ + QE + A+ Sbjct: 2526 AEL-EKAREEAERLAAELERAREEAERLAAELEKAQEEAERLAAELDRAQEEAEKLAADL 2584 Query: 233 K---DEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXX 289 + +E +R D E + +E + L A E +LA EL++ Sbjct: 2585 EKAEEEAERQKADNERLAAELDRAQEEAERLAAELERAQEEAERLAAELDRAQEEAERLA 2644 Query: 290 XXXXXLAKQSIEPSCEEKTEIEEKGSLEIAN----MTELTKKIELLEHLNCQIRQTNKEL 345 A++ E + + EE+ + A+ EL + E E L ++ + +E Sbjct: 2645 AELDR-AQEEAEKLAADLEKAEEEAERQKADNERLAAELNRAQEEAERLAAELEKAQEEA 2703 Query: 346 ENKLATMG----------TESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLN 395 E A + +++ +++ +++ + + R + +Q +E L Sbjct: 2704 EKLAADLEKAEEDAERQKADNRRLAADNERLAAELDRAQEEAERLAAELDRAQEEAERLA 2763 Query: 396 QDTDKKINKNE--IAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQL- 452 + D+ + E A LE + + D + ++ + + L A+L Sbjct: 2764 AELDRAQEEAEKLAADLEKAEEDAERQKADNRRLAADNERLAAELDRAQEEAERLAAELD 2823 Query: 453 QLEHQQHMEGPSLIHVGTNTE----DVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSA 508 + + + L + E D +A E+L EL D ++ + L +L A Sbjct: 2824 RAQEEAEKLAADLEKAEEDAERQKADNRRLAADNERLAAEL-DRAQE-EAERLAAELDRA 2881 Query: 509 EEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLS 568 +E+ +L E+D A ++ + K++++ ++ + ++ + N+ RLT EL Sbjct: 2882 QEEAERLAAELDRAQEDAERQKADNRRLAAELDRAQEDAERQKADNR---RLTGELADKE 2938 Query: 569 QKVAELEEEK 578 +++A E++ Sbjct: 2939 RELAAFREKR 2948 >UniRef50_O96133 Cluster: Putative uncharacterized protein PFB0145c; n=1; Plasmodium falciparum 3D7|Rep: Putative uncharacterized protein PFB0145c - Plasmodium falciparum (isolate 3D7) Length = 1979 Score = 131 bits (317), Expect = 1e-28 Identities = 202/1096 (18%), Positives = 466/1096 (42%), Gaps = 73/1096 (6%) Query: 503 EKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSK--VSDSNKEIVRL 560 E + + + ++ D+ K +I+ K K K K DN ++ ++++N Sbjct: 22 ESFNEEDNENNEKREKSDSWYKKIIETKGKSKTKYKNDNSLDDNINEDIINNNNNNNNDN 81 Query: 561 TEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMI----EMENLAETRLKAI 616 + ++ + + N + D ++ ++ K +I E+EN + LK+I Sbjct: 82 NNDNNNDNNNDNNNDNNNDNNNENNNDNNNFNNYSDEISKNIIHKDNELENQLKDTLKSI 141 Query: 617 SLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKK 676 S L ++ + ++ L+++ EV+DK D + ++ + K ++++ID L+ +K Sbjct: 142 SSLSNKIVNYESKIEELEKELKEVKDKNIDNNDYENKL---KEKEDFVKQKIDMLN--EK 196 Query: 677 ELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELL 736 E L + L ++K + K + +++I+ K + + + +K ++ I E++ Sbjct: 197 ENLLQEKELDINKRE-----KKINEKEKNIIKKEETFHNIEKEYLEKNKERETISI-EII 250 Query: 737 AKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLE 796 H E+ KI+ + + ++ + + + E+ L + K + E+I + D E Sbjct: 251 DIKKHLEKLKIEIKEKKE-DLENLNKKLLSKENVLKELKGCVKEKNETINSLNDNIIEKE 309 Query: 797 RKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQ 856 +K L L+EK K QE E + +R EK+ E + KEL+ + Sbjct: 310 KKYKLLEYELEEKNKQIDLLNKQEKEKEKEKEREKEKEREKEKEK-EYDTLIKELKDEKI 368 Query: 857 ILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQT 916 +LE+ ++++ D+++ + + ++ ++ K QL+ + +K + +T Sbjct: 369 SILEKVHSIKVREMDIEKREHNFLHMEDQLKDLKNSFVKNNNQLKVYKCEIKNL----KT 424 Query: 917 LIVQKKKEIEDLEIEFNTQIESAI-----RDKKVL----NEKYE--------KNIEYVTQ 959 + +K+KE++D+E +I I ++K++L N K E K +T+ Sbjct: 425 ELEKKEKELKDIENVSKEEINKLINQLNEKEKQILAFNKNHKEEIHGLKEELKESVKITK 484 Query: 960 LEAQ-LQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALL 1018 +E Q LQE + + ++E +E I + K++ + Y YI EIN LN L Sbjct: 485 IETQELQEMVDIKQKELDQLQEKYNAQIESISIELSKKEKEYNQYKNTYIEEINNLNEKL 544 Query: 1019 KQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHN 1078 ++ ++E L N + + + T++ ++ ++ +++Q+ Sbjct: 545 EETNKEYTNLQNNYTNEINMLNNDIHMLNGNIKTMNTQISTLKNDVHLLNEQIDKLNNEK 604 Query: 1079 EELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXX 1138 L + E + QI +LKE K I I T M + N + Sbjct: 605 GTLNSKISELNVQIMDLKEEKDFLNNQIVDLSNQIDLLT-RKMEEKENKMLEQENKYKQE 663 Query: 1139 XXXLK---------VQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQL-ETLNTELTGH 1188 L+ + +EE + L + +++ +E K+ +L + + + Sbjct: 664 MELLRGNIKSSENILNNDEEVCDLKRKLSLKESEMKMMKEEHDKKLAELKDDCDVRIREM 723 Query: 1189 DVVNQEQINQLKSKLE-QLNT---ENDNLLSTVAEL-RSSISSAVDQRGFEIAELWKQHL 1243 + N+++IN LK + E ++NT +N++ ++T+ E I++ ++ +I + +++ Sbjct: 724 NEKNEDKINMLKEEYEDKINTLKEQNEDKINTLKEQNEDKINTLKEEYEHKINTMKEEYE 783 Query: 1244 AQREADFQKTEHELRVQLSAFESKYEQLLDSVQS--STQEETNKIVTMEQVTSLQNKLQD 1301 + ++ EH++ E K + + + +T E N+ +++ SL+ + ++ Sbjct: 784 HKINTLNEQNEHKINTLNEQNEHKINTMKEEYEDKMNTLNEQNE----DKMNSLKEEYEN 839 Query: 1302 KEEHLRNLQE-KYADVIN----QIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTEN 1356 K + + E K DV+N +++ L+ ++++K F L TE Sbjct: 840 KINQINSNNEIKIKDVVNEYIEEVDKLKVTLDEKKKQFDKEINYAHIKAHEKEQILLTEM 899 Query: 1357 QSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEI 1416 + K ++ ++ E+ +L KS D ++ E + + E+ Sbjct: 900 EELKCQRDNKYSDLYEKYIKLIKSICMIINIECCDDIENEDIIRRIEEYINNNKGLKKEV 959 Query: 1417 YQKTHE--YTITLTQRNDEF--ENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANH 1472 +K H+ + + + ++F ++ + E +K+ E K+ E+ K+ E N Sbjct: 960 EEKEHKRHSSFNILKSKEKFFKNSIEDKSHELKKKHEKDLLSKDKEIEEKNKKIKELNND 1019 Query: 1473 YETMQKESEI-ERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEI 1531 + +Q E + ++ ++++ K + L + E K E ++ + L+ ++ Sbjct: 1020 IKKLQDEILVYKKQSNAQQVDHKKKSWILLKDKSKEKIKDKENQINVEKNEEKDLKKKDD 1079 Query: 1532 EIVTLNDEITNLQNMV 1547 EI LN+E+ + ++ Sbjct: 1080 EIRILNEELVKYKTIL 1095 Score = 119 bits (287), Expect = 6e-25 Identities = 218/1189 (18%), Positives = 512/1189 (43%), Gaps = 129/1189 (10%) Query: 475 VNEIAKVQEQLKQELNDEIKDVNV--KDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSN 532 VN +K++E L++EL E+KD N+ D KLK E+ + Q D ++ +N+++ K Sbjct: 149 VNYESKIEE-LEKELK-EVKDKNIDNNDYENKLKEKEDFVKQKIDMLNE-KENLLQEK-- 203 Query: 533 HKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSG- 591 +L + + +K K+++ K I++ E H++ ++ E +E+ + + ++D Sbjct: 204 -ELDINKREK------KINEKEKNIIKKEETFHNIEKEYLEKNKERETISIEIIDIKKHL 256 Query: 592 RMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQ 651 ++ ++ +K ++ENL + L ++L+ K + ++ + D + +K L+ Sbjct: 257 EKLKIEIKEKKEDLENLNKKLLSKENVLKELKGCVKEKNETINSLNDNIIEKEKKYKLLE 316 Query: 652 SDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGT-IKDLENDKEDIMNKL 710 + + + K + L + + +KE E K +KE+ Y T IK+L+++K I+ K+ Sbjct: 317 YE-LEEKNKQIDLLNKQEKEKEKEKEREKEKEREK-EKEKEYDTLIKELKDEKISILEKV 374 Query: 711 QNYIQENMDLTDKLEKM--SAEKISELLAK-INHEEQSKIQT----QFGIDAKIQERDLY 763 + MD+ + +++ +L + + Q K+ + + +E++L Sbjct: 375 HSIKVREMDIEKREHNFLHMEDQLKDLKNSFVKNNNQLKVYKCEIKNLKTELEKKEKELK 434 Query: 764 -IENI-ESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQED 821 IEN+ + E++K +++ E+ I + + L L+E K T + Sbjct: 435 DIENVSKEEINKLINQLNEKEKQILAFNKNH---KEEIHGLKEELKESVKITKIETQELQ 491 Query: 822 ELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVE 881 E+V+ + D++ EK +IE + EL KK + E NQ + ++ + N +E Sbjct: 492 EMVD--IKQKELDQLQEKYNAQIESISIELSKKEK---EYNQYKNTYIEEIN-NLNEKLE 545 Query: 882 KANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIR 941 + N+ + Y ++ L +++ + +T+ Q D+ + N QI+ Sbjct: 546 ETNKE--YTNLQNNYTNEINMLNNDIHMLNGNIKTMNTQISTLKNDVHL-LNEQIDKLNN 602 Query: 942 DKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSP 1001 +K LN K +++L Q+ + K + LN + +L+ ++L+ + +++++ + Sbjct: 603 EKGTLNSK-------ISELNVQIMDLKEEKDFLNNQIVDLSNQ-IDLLTRKMEEKENKML 654 Query: 1002 DYTEQYINEINKLNALLKQK------DEEIIALNQKINNAQVSYMSMVSDYESKLAQFTT 1055 + +Y E+ L +K DEE+ L +K++ + M +++ KLA+ Sbjct: 655 EQENKYKQEMELLRGNIKSSENILNNDEEVCDLKRKLSLKESEMKMMKEEHDKKLAELKD 714 Query: 1056 KL--------ENMEEEMQRVSKQLLDS----KQHNEE-LQILVREQDDQIKELKETKLTF 1102 E E+++ + ++ D K+ NE+ + L + +D+I LKE + Sbjct: 715 DCDVRIREMNEKNEDKINMLKEEYEDKINTLKEQNEDKINTLKEQNEDKINTLKE-EYEH 773 Query: 1103 EMNIPKTEGMIISSTIEPMSDDANN---------VDXXXXXXXXXXXXLKVQEEEEFIQE 1153 ++N K E +T+ ++ N ++ L Q E++ Sbjct: 774 KINTMKEEYEHKINTLNEQNEHKINTLNEQNEHKINTMKEEYEDKMNTLNEQNEDKMNSL 833 Query: 1154 RSVLQEQSAKLNT----ELQECYTKIIQ-LETLNTELTGHDVVNQEQINQ---------- 1198 + + + ++N+ ++++ + I+ ++ L L ++IN Sbjct: 834 KEEYENKINQINSNNEIKIKDVVNEYIEEVDKLKVTLDEKKKQFDKEINYAHIKAHEKEQ 893 Query: 1199 -LKSKLEQLNTENDNLLSTVAE-----LRS-----SISSAVDQRGFEIAELWKQHLAQRE 1247 L +++E+L + DN S + E ++S +I D +I ++++ + Sbjct: 894 ILLTEMEELKCQRDNKYSDLYEKYIKLIKSICMIINIECCDDIENEDIIRRIEEYINNNK 953 Query: 1248 A---DFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEE 1304 + ++ EH+ + +SK + +S++ + E K + + S ++++K + Sbjct: 954 GLKKEVEEKEHKRHSSFNILKSKEKFFKNSIEDKSHELKKK--HEKDLLSKDKEIEEKNK 1011 Query: 1305 HLRNLQEKYADVINQIEILRSE-----IEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSY 1359 ++ L + ++I + + + ++ +K ++ + E Sbjct: 1012 KIKELNNDIKKLQDEILVYKKQSNAQQVDHKKKSWILLKDKSKEKIKDKENQINVEKNEE 1071 Query: 1360 KQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQK 1419 K ++++ I N +L K + D +K+ + L + + K Sbjct: 1072 KDLKKKDD-EIRILNEELVKYKTILYNLKKDPLLQNQDLLSKID--INSLTINEGMCVDK 1128 Query: 1420 THEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYE------KESELAILRLKMHENANHY 1473 E+ + ++E R L + + I LT E K++EL K++ Sbjct: 1129 IEEHILDY---DEEINKSRSNLFQLKNEICSLTTEVMELNNKKNELIEENNKLNLVDQGK 1185 Query: 1474 ETMQKESEIERVKLIEELNVKITESVS----LNKQVAELNKALEEEVAKTNEMQTALENQ 1529 + ++K+ E ++ K IE+LN ++T+ LN++V +LN E + +N++ + + Sbjct: 1186 KKLKKDVEKQK-KEIEKLNKQLTKCNKQIDELNEEVEKLNNENIELITYSNDLNNKFDMK 1244 Query: 1530 EIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNK 1578 E ++ DE + +++ ++K + + D K+ +++N K Sbjct: 1245 ENNLMMKLDENEDNIKKMKSKIDDMEKEIKYREDEKKRNLNEINNLKKK 1293 Score = 115 bits (277), Expect = 9e-24 Identities = 260/1357 (19%), Positives = 562/1357 (41%), Gaps = 122/1357 (8%) Query: 90 ISESLANTLKQKEILMEKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQ--LGDVTHL 147 I+E N +K++E K+Y E +K T + + D+ +L Sbjct: 214 INEKEKNIIKKEETFHNIEKEYLEKNKERETISIEIIDIKKHLEKLKIEIKEKKEDLENL 273 Query: 148 SNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXX 207 + + K+N L L+ +K TI L + I EK++ K Sbjct: 274 NKKLLSKENVLKELKGCVKEKNETINSLNDNIIEKEK------KYKLLEYELEEKNKQID 327 Query: 208 XXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEI 267 ++ +++ K +E E E + E L+K++ KD +IS LE+ + + Sbjct: 328 LLNKQEKEKEKEKEREKEKEREKEKEKEYDTLIKEL--KDEKISILEKVHSIKVREMDIE 385 Query: 268 SLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIE--EKGSLEIANMT--E 323 EH+ L E +Q L E KTE+E EK +I N++ E Sbjct: 386 KREHNFLHME-DQLKDLKNSFVKNNNQLKVYKCEIK-NLKTELEKKEKELKDIENVSKEE 443 Query: 324 LTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMK 383 + K I L QI NK + ++ + E K S K + + +++ K K Sbjct: 444 INKLINQLNEKEKQILAFNKNHKEEIHGLKEELK----ESVKITKIETQELQEMVDIKQK 499 Query: 384 SPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXX 443 QL + Q I E++K E +++ ++EK Sbjct: 500 E-LDQLQEKYNAQIESISI---ELSKKEKEYNQYKNTYIEEINNLNEKLEETNKEYTNLQ 555 Query: 444 GKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDV-NEIAKVQEQLKQELNDEIKDVNVKDLI 502 T + L + HM ++ + T + N++ + EQ+ +LN+E +N Sbjct: 556 NNYTNEINM-LNNDIHMLNGNIKTMNTQISTLKNDVHLLNEQI-DKLNNEKGTLN----- 608 Query: 503 EKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTE 562 K+ QI L +E D N ++ + + L ++M++ + + + K+ + L Sbjct: 609 SKISELNVQIMDLKEEKDFLNNQIVDLSNQIDLLTRKMEEKENKMLEQENKYKQEMELLR 668 Query: 563 ELHHLSQKVAELEEEKGNLQLHLVDYDSG-RMIESDVYKKMIEMENLAETRLKAISLLES 621 S+ + +EE +L+ L +S +M++ + KK+ E+++ + R++ ++ Sbjct: 669 GNIKSSENILNNDEEVCDLKRKLSLKESEMKMMKEEHDKKLAELKDDCDVRIREMNEKNE 728 Query: 622 QKFDLVQELH--ILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELA 679 K ++++E + + ++ EDK+ + + D++ + +K EE ++ K+E Sbjct: 729 DKINMLKEEYEDKINTLKEQNEDKINTLKEQNEDKI-NTLK----EEYEHKINTMKEEYE 783 Query: 680 LVIENLKLDKEQLYGTIKD-----LENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISE 734 I L E T+ + + KE+ +K+ ++N D + L++ KI++ Sbjct: 784 HKINTLNEQNEHKINTLNEQNEHKINTMKEEYEDKMNTLNEQNEDKMNSLKEEYENKINQ 843 Query: 735 LLAK--------INH--EEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEES 784 + + +N EE K++ K ++++ +I++ K + + +EE Sbjct: 844 INSNNEIKIKDVVNEYIEEVDKLKVTLDEKKKQFDKEINYAHIKAH-EKEQILLTEMEE- 901 Query: 785 IAVMEDRRYS-LERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLE 843 + D +YS L K +L + I+ ++++ R+ +++++ ++K++ E Sbjct: 902 LKCQRDNKYSDLYEKYIKLIKSICMIINIECCDDIENEDIIRRIEEYINNNKGLKKEVEE 961 Query: 844 IEH---------ENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESEST 894 EH ++KE KN I + ++ + D+ + EK + ++ Sbjct: 962 KEHKRHSSFNILKSKEKFFKNSIEDKSHELKKKHEKDLLSKDKEIEEKNKKIKELNNDIK 1021 Query: 895 KYQTQL--RDLESNLKRITHEHQTLIVQK---KKEIEDLEIEFNTQ--IESAIRDK---- 943 K Q ++ +SN +++ H+ ++ I+ K K++I+D E + N + E ++ K Sbjct: 1022 KLQDEILVYKKQSNAQQVDHKKKSWILLKDKSKEKIKDKENQINVEKNEEKDLKKKDDEI 1081 Query: 944 KVLNE---KYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNK-MNLELIDKHV---QKQ 996 ++LNE KY K I Y + + LQ ++ + +++N +N+ M ++ I++H+ ++ Sbjct: 1082 RILNEELVKY-KTILYNLKKDPLLQN-QDLLSKIDINSLTINEGMCVDKIEEHILDYDEE 1139 Query: 997 QTQSPDYTEQYINEINKLNA---LLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQF 1053 +S Q NEI L L K E+I N K+N + D E + Sbjct: 1140 INKSRSNLFQLKNEICSLTTEVMELNNKKNELIEENNKLNLVDQGKKKLKKDVEKQ---- 1195 Query: 1054 TTKLENMEEEMQRVSKQLLD-----SKQHNEELQILVREQDDQIK-ELKETKLTFEMNIP 1107 ++E + +++ + +KQ+ + K +NE ++++ D K ++KE L +++ Sbjct: 1196 KKEIEKLNKQLTKCNKQIDELNEEVEKLNNENIELITYSNDLNNKFDMKENNLMMKLDEN 1255 Query: 1108 KTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSV------LQEQS 1161 + + S I+ M + + LK + E+ I+ + + + Sbjct: 1256 EDNIKKMKSKIDDMEKEIKYREDEKKRNLNEINNLKKKNEDMCIKYNEMNIKYGDICVKY 1315 Query: 1162 AKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELR 1221 +++ +E K Q++ E + Q ++ + +++N + LL+ + Sbjct: 1316 EEMSLTYKETSLKYEQIKVKYDEKCSQYDEIRFQYDEKCFQYDEINKKYGALLN-INITN 1374 Query: 1222 SSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQE 1281 + S VD+ EI + + + A++ K EL ++ + + ++ + E Sbjct: 1375 KMVDSKVDRNNNEIISV--DNKVEGIANYLKQIFELNEEIIRLKGEINKISLLYSNELNE 1432 Query: 1282 ETNKIVTM----EQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXX 1337 + + + M EQ+ L+ ++ EE + NL +Y+D + + ++ K+ Sbjct: 1433 KNSYDINMKHIQEQLLFLEKTNKENEEKIINLTSQYSDA------YKKKSDESKLCGAQF 1486 Query: 1338 XXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEEN 1374 ++RT Y++M + NI E+N Sbjct: 1487 VDDVNIYGNISNNNIRTNEYKYEEMFD---TNIEEKN 1520 Score = 109 bits (262), Expect = 6e-22 Identities = 256/1250 (20%), Positives = 552/1250 (44%), Gaps = 99/1250 (7%) Query: 143 DVTHLSNTIKEKDN----ALSVLQVKMKIMETTILDL---QEKINEKDQ-IIEAKNKATT 194 D N +KEK++ + +L K +++ LD+ ++KINEK++ II+ + Sbjct: 171 DNNDYENKLKEKEDFVKQKIDMLNEKENLLQEKELDINKREKKINEKEKNIIKKEETFHN 230 Query: 195 XXXXXXXXXXXXXXXXXE--DTKQQMTKMQENFIAMEAEWKDEKQRLL-KDIESKDVRIS 251 E D K+ + K++ + + ++ ++LL K+ K+++ Sbjct: 231 IEKEYLEKNKERETISIEIIDIKKHLEKLKIEIKEKKEDLENLNKKLLSKENVLKELK-G 289 Query: 252 SLEEANKLLEAARFEISLEHSK---LAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKT 308 ++E N+ + + I + K L ELE+ K+ E E++ Sbjct: 290 CVKEKNETINSLNDNIIEKEKKYKLLEYELEEKNKQIDLLNKQEKEKEKEK-EREKEKER 348 Query: 309 EIEEKGSLEIANMTELTKKIELLEHL-NCQIRQTN-KELENKLATMGTESKAV-SSPSKK 365 E E++ + +KI +LE + + ++R+ + ++ E+ M + K + +S K Sbjct: 349 EKEKEKEYDTLIKELKDEKISILEKVHSIKVREMDIEKREHNFLHMEDQLKDLKNSFVKN 408 Query: 366 GSPL-ISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINK--NEIAKLEMVIQSLNKDLV 422 + L + + +N ++++ +L + + + ++INK N++ + E I + NK+ Sbjct: 409 NNQLKVYKCEIKNLKTELEKKEKEL--KDIENVSKEEINKLINQLNEKEKQILAFNKNHK 466 Query: 423 DKEYVISE--KDTXXXXXXXXXXGKDTL------IAQLQLEHQQHMEGPSLIHVGTNTED 474 ++ + + E K++ ++ + + QLQ ++ +E S I + ++ Sbjct: 467 EEIHGLKEELKESVKITKIETQELQEMVDIKQKELDQLQEKYNAQIESIS-IELSKKEKE 525 Query: 475 VNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHK 534 N+ + LN+++++ N K+ + +I LN++I N N IK + Sbjct: 526 YNQYKNTYIEEINNLNEKLEETN-KEYTNLQNNYTNEINMLNNDIHMLNGN-IKTMNTQI 583 Query: 535 LKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMI 594 LK ++ ++ N E L ++ L+ ++ +L+EEK L +VD + I Sbjct: 584 STLKNDVHLLN--EQIDKLNNEKGTLNSKISELNVQIMDLKEEKDFLNNQIVDLSN--QI 639 Query: 595 ESDVYKKMIEMEN-LAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSD 653 + + +KM E EN + E K +E + ++ +IL +EV D +S +S+ Sbjct: 640 DL-LTRKMEEKENKMLEQENKYKQEMELLRGNIKSSENILNND-EEVCDLKRKLSLKESE 697 Query: 654 -QVCSEIKSVHLEEQIDALSASKKELALVIEN-LKLDKEQLYGTIKDLENDKEDIMNKLQ 711 ++ E L E D +E+ E+ + + KE+ I L+ ED +N L+ Sbjct: 698 MKMMKEEHDKKLAELKDDCDVRIREMNEKNEDKINMLKEEYEDKINTLKEQNEDKINTLK 757 Query: 712 NYIQENMDLTDKLEKMSAEKISELLAKINHEEQS-KIQTQFGIDAKIQERDLYIENIESE 770 ++N D + L++ KI+ + + H+ + Q + I+ ++ + I ++ E Sbjct: 758 ---EQNEDKINTLKEEYEHKINTMKEEYEHKINTLNEQNEHKINTLNEQNEHKINTMKEE 814 Query: 771 LSKYKSRICRL-EESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAV 829 Y+ ++ L E++ M + E K +Q+ S + K K I+E V++L V Sbjct: 815 ---YEDKMNTLNEQNEDKMNSLKEEYENKINQINSNNEIKIKDVVNEYIEE---VDKLKV 868 Query: 830 LMDHDRVVEKQL-LEIEHENKELQKKNQILLEENQNLQI----SLSDMQQHYNALVEK-- 882 +D + KQ EI + + + +K QILL E + L+ SD+ + Y L++ Sbjct: 869 TLDEKK---KQFDKEINYAHIKAHEKEQILLTEMEELKCQRDNKYSDLYEKYIKLIKSIC 925 Query: 883 --ANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAI 940 N + E+ ++ + +N K + E + ++ L+ + +++I Sbjct: 926 MIINIECCDDIENEDIIRRIEEYINNNKGLKKEVEEKEHKRHSSFNILKSK-EKFFKNSI 984 Query: 941 RDKK-VLNEKYEKNI----EYVTQLEAQLQEYKNNIENLNMNVEELNKM-NLELIDKHVQ 994 DK L +K+EK++ + + + +++E N+I+ L + K N + +D H + Sbjct: 985 EDKSHELKKKHEKDLLSKDKEIEEKNKKIKELNNDIKKLQDEILVYKKQSNAQQVD-HKK 1043 Query: 995 KQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFT 1054 K D +++ I + K N + +K+EE L +K + ++ +V Y++ L + Sbjct: 1044 KSWILLKDKSKEKIKD--KENQINVEKNEE-KDLKKKDDEIRILNEELVK-YKTIL--YN 1097 Query: 1055 TKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMII 1114 K + + + +SK ++S NE + V + ++ I + E N+ + + I Sbjct: 1098 LKKDPLLQNQDLLSKIDINSLTINEGM--CVDKIEEHILDYDEEINKSRSNLFQLKNEIC 1155 Query: 1115 SSTIEPMS-DDANN--VDXXXXXXXXXXXXLKVQEE-EEFIQERSVLQEQSAKLNTELQE 1170 S T E M ++ N ++ K++++ E+ +E L +Q K N ++ E Sbjct: 1156 SLTTEVMELNNKKNELIEENNKLNLVDQGKKKLKKDVEKQKKEIEKLNKQLTKCNKQIDE 1215 Query: 1171 CYTKIIQLETLNTELT--GHDVVNQEQI--NQLKSKLEQLNTENDNLLSTVAELRSSISS 1226 ++ +L N EL +D+ N+ + N L KL++ + S + ++ I Sbjct: 1216 LNEEVEKLNNENIELITYSNDLNNKFDMKENNLMMKLDENEDNIKKMKSKIDDMEKEIKY 1275 Query: 1227 AVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQL-LDSVQSSTQEETNK 1285 D++ + E+ +L ++ D +E+ ++ KYE++ L ++S + E K Sbjct: 1276 REDEKKRNLNEI--NNLKKKNEDMCIKYNEMNIKYGDICVKYEEMSLTYKETSLKYEQIK 1333 Query: 1286 IVTME---QVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKV 1332 + E Q ++ + +K + +KY ++N I I +++ D KV Sbjct: 1334 VKYDEKCSQYDEIRFQYDEKCFQYDEINKKYGALLN-INI-TNKMVDSKV 1381 Score = 38.7 bits (86), Expect = 1.3 Identities = 45/226 (19%), Positives = 97/226 (42%), Gaps = 25/226 (11%) Query: 1355 ENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQL-ELKD 1413 +N ++ ++ NI ++ +L+ ++ + E+K+ EL +L E+KD Sbjct: 108 DNNNFNNYSDEISKNIIHKDNELENQLKDTLKSISSLSNKIVNYESKIEELEKELKEVKD 167 Query: 1414 SEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHY 1473 I N+++EN ++ ++ K+ D+ EKE+ L L + N Sbjct: 168 KNI-------------DNNDYENKLKEKEDFVKQKIDMLNEKENLLQEKELDI--NKREK 212 Query: 1474 ETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEI 1533 + +KE I +K E + ++ K+ E NK E + +++ LE +IEI Sbjct: 213 KINEKEKNI--IKKEETFH-------NIEKEYLEKNKERETISIEIIDIKKHLEKLKIEI 263 Query: 1534 VTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKE 1579 +++ NL + + + +++ + + + DN + KE Sbjct: 264 KEKKEDLENLNKKLLSKENVLKELKGCVKEKNETINSLNDNIIEKE 309 >UniRef50_Q15075 Cluster: Early endosome antigen 1; n=30; Euteleostomi|Rep: Early endosome antigen 1 - Homo sapiens (Human) Length = 1411 Score = 131 bits (317), Expect = 1e-28 Identities = 244/1161 (21%), Positives = 496/1161 (42%), Gaps = 126/1161 (10%) Query: 477 EIAKVQEQLKQELNDEIK-DVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKL 535 E+ K E+ + E K D V D +L+S E+Q+ +E N N+ ++K + Sbjct: 108 ELKKELEKYQGLQQQEAKPDGLVTDSSAELQSLEQQL----EEAQTENFNIKQMKDLFEQ 163 Query: 536 KLKQMQKTIDNFSKVSDSNK--------EIVRLTEELHHLSQKVAELEEEKGNLQLHLVD 587 K Q+ I + D + ++ RLTEEL+ + + +L+ E L Sbjct: 164 KAAQLATEIADIKSKYDEERSLREAAEQKVTRLTEELNKEATVIQDLKTEL----LQRPG 219 Query: 588 YDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADI 647 + +++ ++ + M+N+ R + ES+K L E LQ +Y E A I Sbjct: 220 IEDVAVLKKELVQVQTLMDNMTLERER-----ESEK--LKDECKKLQSQYASSE---ATI 269 Query: 648 SQLQSDQVCSEIKSVHLEEQIDALSASKKELA----LVIENLKLDKEQLYGTIKDLENDK 703 SQL+S+ + +++ L +S EL + ENL L KEQ Y +++ N++ Sbjct: 270 SQLRSELAKGPQEVAVYVQELQKLKSSVNELTQKNQTLTENL-LKKEQDYTKLEEKHNEE 328 Query: 704 EDIMNKLQNYI-QENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDL 762 +Q + Q+++D ++SA + S L +I+ E K + K++E Sbjct: 329 SVSKKNIQATLHQKDLDCQQLQSRLSASETS--LHRIHVELSEKGEAT----QKLKEE-- 380 Query: 763 YIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEY--TIQE 820 + +E++ K+ +L++ E L+ + +QL S L E ++ E ++E Sbjct: 381 -LSEVETKYQHLKAEFKQLQQQREEKEQHGLQLQSEINQLHSKLLETERQLGEAHGRLKE 439 Query: 821 DELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALV 880 ++ LMD ++ V L++ ++L++K + + LQ L +Q + Sbjct: 440 QRQLSS-EKLMDKEQQVADLQLKLSRLEEQLKEK----VTNSTELQHQLDKTKQQHQ--- 491 Query: 881 EKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTL-----IVQKKKE----IEDLEIE 931 + L +S + K + DLE L++I + Q + ++QK KE +E + Sbjct: 492 ---EQQALQQSTTAKLREAQNDLEQVLRQIGDKDQKIQNLEALLQKSKENISLLEKERED 548 Query: 932 FNTQIESAIRDKKVLNEKYEKNI---EYVTQLEAQL----QEYKNNIENLNMNVEELNKM 984 +I++ + VLN+ EKN E VTQL +L + +K ENL+ V+E K Sbjct: 549 LYAKIQAGEGETAVLNQLQEKNHTLQEQVTQLTEKLKNQSESHKQAQENLHDQVQE-QKA 607 Query: 985 NLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVS 1044 +L V +T + Q +N+ + Q D +I A + + +A+ + + + Sbjct: 608 HLRAAQDRVLSLETSVNELNSQ----LNESKEKVSQLDIQIKAKTELLLSAEAAKTAQRA 663 Query: 1045 DYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEM 1104 D ++ L L++ ++E+ +++ QL ++ Q + + +KE KE L+ E Sbjct: 664 DLQNHLDTAQNALQDKQQELNKITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQ 723 Query: 1105 NIPKTEGMI---------ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQ---EEEEFIQ 1152 + EG I + ++ E D L Q E+E Sbjct: 724 KTEELEGQIKKLEADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEIVSS 783 Query: 1153 ERSVLQEQSAKLNT-----ELQECYTKIIQ--LETLNTEL-TGHDVVNQEQINQLKSKLE 1204 R LQ++S L + QE +I++ ETL+ E H+ +N +I ++L+ Sbjct: 784 TRLDLQKKSEALESIKQKLTKQEEEKQILKQDFETLSQETKIQHEELN-NRIQTTVTELQ 842 Query: 1205 QLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREA--DFQKT----EHELR 1258 ++ E + L++ ++ ++ +S D +E K++ + A D +KT +H+L+ Sbjct: 843 KVKMEKEALMTELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKELKHQLQ 902 Query: 1259 VQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVIN 1318 VQ+ + ++L S++ ++E + + +E + S+Q +L + L+ +++ + Sbjct: 903 VQMENTLKEQKELKKSLEK--EKEASHQLKLE-LNSMQEQLIQAQNTLKQNEKEEQQLQG 959 Query: 1319 QIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLK 1378 I L+ E +K +L + Q Q + E+ + L+ Sbjct: 960 NINELKQSSEQKKKQI-EALQGELKIAVLQKTELENKLQQQLTQAAQELAAEKEKISVLQ 1018 Query: 1379 KSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVR 1438 + E+++L L K+ E ++L Q D N R Sbjct: 1019 NNYEKSQETFKQLQSDFYGRESELLATRQDL---------KSVEEKLSLAQ-EDLISN-R 1067 Query: 1439 QQLVEYEKRIEDLTYEK---ESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKI 1495 Q+ K I++L K E + A ++ E + +QKE ++ +L+ E + K+ Sbjct: 1068 NQIGNQNKLIQELKTAKATLEQDSAKKEQQLQERCKALQDIQKEKSLKEKELVNEKS-KL 1126 Query: 1496 TESVSL----NKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASS 1551 E + K++ +LN+ L+ ++ + T L++ + ++ E+ + ++A+ Sbjct: 1127 AEIEEIKCRQEKEITKLNEELKSHKLESIKEITNLKDAKQLLIQQKLELQGKADSLKAAV 1186 Query: 1552 SKIQKHVSFASDTKQGRDEQL 1572 + +++ D + +E+L Sbjct: 1187 EQEKRNQQILKDQVKKEEEEL 1207 Score = 131 bits (317), Expect = 1e-28 Identities = 235/1203 (19%), Positives = 501/1203 (41%), Gaps = 95/1203 (7%) Query: 388 QLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKD- 446 + +E N K + + + A+L I + K D+E + E K+ Sbjct: 146 EAQTENFNIKQMKDLFEQKAAQLATEIADI-KSKYDEERSLREAAEQKVTRLTEELNKEA 204 Query: 447 TLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQL---KQELNDEIKDVNVKDLIE 503 T+I L+ E Q P + V +++ ++ + + + ++ ++++KD K L Sbjct: 205 TVIQDLKTELLQR---PGIEDVAVLKKELVQVQTLMDNMTLERERESEKLKD-ECKKLQS 260 Query: 504 KLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEE 563 + S+E I+QL E+ A + V KLK + ++ N +++ ++ Sbjct: 261 QYASSEATISQLRSEL-AKGPQEVAVYVQELQKLKSSVNELTQKNQTLTEN--LLKKEQD 317 Query: 564 LHHLSQKVAELEEEKGNLQ--LHLVDYDSGRM------IESDVYKKMIEMENLAETRLKA 615 L +K E K N+Q LH D D ++ E+ +++ +E+ E K Sbjct: 318 YTKLEEKHNEESVSKKNIQATLHQKDLDCQQLQSRLSASETSLHRIHVELSEKGEATQKL 377 Query: 616 ---ISLLESQKFDLVQELHILQQKYDEVEDK----LADISQLQSDQVCSE--IKSVH--L 664 +S +E++ L E LQQ+ +E E ++I+QL S + +E + H L Sbjct: 378 KEELSEVETKYQHLKAEFKQLQQQREEKEQHGLQLQSEINQLHSKLLETERQLGEAHGRL 437 Query: 665 EEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKL 724 +EQ S + + +L+L +L +K+ + ++ ++L Q++ + L Sbjct: 438 KEQRQLSSEKLMDKEQQVADLQLKLSRLEEQLKEKVTNSTELQHQLDKTKQQHQE-QQAL 496 Query: 725 EKMSAEKISEL---LAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRL 781 ++ + K+ E L ++ + K Q ++A +Q+ I +E E ++I Sbjct: 497 QQSTTAKLREAQNDLEQVLRQIGDKDQKIQNLEALLQKSKENISLLEKEREDLYAKIQAG 556 Query: 782 EESIAVM---EDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVE 838 E AV+ +++ ++L+ + QL L+ + +++ + ++ L +++ H R + Sbjct: 557 EGETAVLNQLQEKNHTLQEQVTQLTEKLKNQSESHKQ---AQENLHDQVQEQKAHLRAAQ 613 Query: 839 KQLLEIEHENKELQKKNQILLEENQNLQISL-SDMQQHYNALVEK-ANRTDLAESESTKY 896 ++L +E EL + E+ L I + + + +A K A R DL T Sbjct: 614 DRVLSLETSVNELNSQLNESKEKVSQLDIQIKAKTELLLSAEAAKTAQRADLQNHLDTA- 672 Query: 897 QTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKV----LNEKYEK 952 Q L+D + L +IT T + Q +++D + E +Q+ES +++ K L +K E+ Sbjct: 673 QNALQDKQQELNKIT----TQLDQVTAKLQDKQ-EHCSQLESHLKEYKEKYLSLEQKTEE 727 Query: 953 NIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEIN 1012 + +LEA E K + E ++++ ++N +L + + T+ E ++ Sbjct: 728 LEGQIKKLEADSLEVKASKEQALQDLQQQRQLNTDL-----ELRATELSKQLEMEKEIVS 782 Query: 1013 KLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLL 1072 L++K E + ++ QK+ + + D+E+ + + E + +Q +L Sbjct: 783 STRLDLQKKSEALESIKQKLTKQEEEKQILKQDFETLSQETKIQHEELNNRIQTTVTELQ 842 Query: 1073 DSKQHNEELQILVREQDDQIKE----LKETKLTFEMNIPKTEGMIISSTIEPMSDDANNV 1128 K E L + D++ + LK +K FE K + I+ +E + + Sbjct: 843 KVKMEKEALMTELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAILD--LEKTCKELKH- 899 Query: 1129 DXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGH 1188 LK Q+E + E+ +E S +L EL ++IQ + + Sbjct: 900 ----QLQVQMENTLKEQKELKKSLEKE--KEASHQLKLELNSMQEQLIQAQNTLKQ---- 949 Query: 1189 DVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREA 1248 N+++ QL+ + +L ++ + L+ + AV Q+ E+ +Q L Q Sbjct: 950 ---NEKEEQQLQGNINELKQSSEQKKKQIEALQGELKIAVLQKT-ELENKLQQQLTQAAQ 1005 Query: 1249 DFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRN 1308 + + ++ V + +E E E+ + T + + S++ KL +E L + Sbjct: 1006 ELAAEKEKISVLQNNYEKSQETFKQLQSDFYGRESELLATRQDLKSVEEKLSLAQEDLIS 1065 Query: 1309 LQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSIL 1368 + + NQ ++++ E++ K L+ + Q K ++E+ ++ Sbjct: 1066 NRNQIG---NQNKLIQ-ELKTAKATLEQDSAKKEQQLQERCKALQ-DIQKEKSLKEKELV 1120 Query: 1369 NINEENAQLKKSSXXXXXXXXXXXXRVNDAEAK-VLELTHQLELKDSEIYQKTH-EYTIT 1426 N + A++++ + + + + E+T+ + K I QK + Sbjct: 1121 NEKSKLAEIEEIKCRQEKEITKLNEELKSHKLESIKEITNLKDAKQLLIQQKLELQGKAD 1180 Query: 1427 LTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVK 1486 + E E QQ+++ + + E+ E + E K+H E K+ E K Sbjct: 1181 SLKAAVEQEKRNQQILKDQVKKEE--EELKKEFIEKEAKLHSEIKEKEVGMKKHEENEAK 1238 Query: 1487 LIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNM 1546 L ++IT +LN+ + + K + + +E++ ++ EI L + N Q+ Sbjct: 1239 ----LTMQIT---ALNENLGTVKKEWQSSQRRVSELEKQTDDLRGEIAVLEATVQNNQDE 1291 Query: 1547 VRA 1549 RA Sbjct: 1292 RRA 1294 Score = 120 bits (290), Expect = 3e-25 Identities = 222/1145 (19%), Positives = 477/1145 (41%), Gaps = 110/1145 (9%) Query: 212 EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRI--SSLEEANKLLEAARFEISL 269 E +Q++T++ E +D K LL+ +DV + L + L++ E Sbjct: 187 EAAEQKVTRLTEELNKEATVIQDLKTELLQRPGIEDVAVLKKELVQVQTLMDNMTLERER 246 Query: 270 EHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIE 329 E KL E ++ L + + E ++E L+ +++ ELT+K + Sbjct: 247 ESEKLKDECKKLQSQYASSEATISQLRSELAKGPQEVAVYVQELQKLK-SSVNELTQKNQ 305 Query: 330 LLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQL 389 L + Q +LE K K + + + + R +AS+ + Sbjct: 306 TLTENLLKKEQDYTKLEEKHNEESVSKKNIQATLHQKDLDCQQLQSRLSASETSLHRIHV 365 Query: 390 SSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLI 449 + T K K E++++E Q L + + EK+ Sbjct: 366 ELSEKGEATQKL--KEELSEVETKYQHLKAEFKQLQQQREEKEQHG-------------- 409 Query: 450 AQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQE-LNDEIKDVNVKDLIEKLKSA 508 LQL+ + + L+ + + K Q QL E L D K+ V DL KL Sbjct: 410 --LQLQSEINQLHSKLLETERQLGEAHGRLKEQRQLSSEKLMD--KEQQVADLQLKLSRL 465 Query: 509 EEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLS 568 EEQ+ + + K K H+ + Q T +K+ ++ ++ ++ ++ Sbjct: 466 EEQLKEKVTNSTELQHQLDKTKQQHQEQQALQQSTT---AKLREAQNDLEQVLRQIGDKD 522 Query: 569 QKVAELEE--EKGNLQLHLVDYDSGRMIESDVYKKMI--EMENLAETRLKAIS-LLESQK 623 QK+ LE +K + L++ + D+Y K+ E E +L+ + L+ Q Sbjct: 523 QKIQNLEALLQKSKENISLLEKE-----REDLYAKIQAGEGETAVLNQLQEKNHTLQEQV 577 Query: 624 FDLVQELHILQQKYDEVEDKLADISQLQSDQV-CSEIKSVHLEEQIDALSA----SKKEL 678 L ++L + + + ++ L D Q Q + ++ + + LE ++ L++ SK+++ Sbjct: 578 TQLTEKLKNQSESHKQAQENLHDQVQEQKAHLRAAQDRVLSLETSVNELNSQLNESKEKV 637 Query: 679 ALVIENLKLDKEQLYGTIK-------DLENDKEDIMNKLQNYIQENMDLTDKLEKMSA-- 729 + + +K E L DL+N + N LQ+ QE +T +L++++A Sbjct: 638 SQLDIQIKAKTELLLSAEAAKTAQRADLQNHLDTAQNALQDKQQELNKITTQLDQVTAKL 697 Query: 730 EKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVME 789 + E +++ + + ++ K +E + I+ +E++ + K+ + + + Sbjct: 698 QDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQIKKLEADSLEVKASKEQALQDLQQQR 757 Query: 790 DRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDH--DRVVEKQLLEIEHE 847 LE +A +L L+ +++ S + + L + + EKQ+L+ + E Sbjct: 758 QLNTDLELRATELSKQLEMEKEIVSSTRLDLQKKSEALESIKQKLTKQEEEKQILKQDFE 817 Query: 848 NKELQKKNQILLEE-NQNLQISLSDMQQHYNALVEKANRTDLA--ESESTKYQTQLRDLE 904 L ++ +I EE N +Q +++++Q+ + ++A T+L+ + + +K L++ + Sbjct: 818 T--LSQETKIQHEELNNRIQTTVTELQKV--KMEKEALMTELSTVKDKLSKVSDSLKNSK 873 Query: 905 SNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQL 964 S ++ + + I+ +K ++L+ + Q+E+ ++++K L + EK E QL+ Sbjct: 874 SEFEKENQKGKAAILDLEKTCKELKHQLQVQMENTLKEQKELKKSLEKEKEASHQLKL-- 931 Query: 965 QEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEE 1024 ELN M +LI +Q + + +Q IN+L +QK ++ Sbjct: 932 ---------------ELNSMQEQLIQAQNTLKQNEKEE--QQLQGNINELKQSSEQKKKQ 974 Query: 1025 IIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQIL 1084 I AL ++ A + + + + +L Q +L +E++ + S++ ++LQ Sbjct: 975 IEALQGELKIAVLQKTELENKLQQQLTQAAQELAAEKEKISVLQNNYEKSQETFKQLQSD 1034 Query: 1085 VREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKV 1144 ++ ++ ++ + E + + +IS+ N + Sbjct: 1035 FYGRESELLATRQDLKSVEEKLSLAQEDLISNR--------NQIGNQNKLI--------- 1077 Query: 1145 QEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLE 1204 +E ++ L++ SAK +LQE + L+ + E + + +E +N+ KSKL Sbjct: 1078 ---QELKTAKATLEQDSAKKEQQLQE---RCKALQDIQKEKS---LKEKELVNE-KSKLA 1127 Query: 1205 QLNTENDNLLSTVAELRSSISSAVDQRGFEIAELW--KQHLAQREADFQKTEHELRVQLS 1262 ++ + +L + S + EI L KQ L Q++ + Q L+ + Sbjct: 1128 EIEEIKCRQEKEITKLNEELKSHKLESIKEITNLKDAKQLLIQQKLELQGKADSLKAAVE 1187 Query: 1263 AFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEI 1322 E + +Q+L Q +EE K +E+ L +++++KE ++ +E A + QI Sbjct: 1188 Q-EKRNQQILKD-QVKKEEEELKKEFIEKEAKLHSEIKEKEVGMKKHEENEAKLTMQITA 1245 Query: 1323 LRSEI 1327 L + Sbjct: 1246 LNENL 1250 Score = 110 bits (265), Expect = 3e-22 Identities = 205/933 (21%), Positives = 384/933 (41%), Gaps = 72/933 (7%) Query: 162 QVKMKIMETTILDLQ-EKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQ--- 217 Q+K K+ +T L Q +K ++ Q +A ++TT D Q+ Sbjct: 468 QLKEKVTNSTELQHQLDKTKQQHQEQQALQQSTTAKLREAQNDLEQVLRQIGDKDQKIQN 527 Query: 218 ----MTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLE------AARFEI 267 + K +EN +E E +D ++ E + ++ L+E N L+ + + Sbjct: 528 LEALLQKSKENISLLEKEREDLYAKIQAG-EGETAVLNQLQEKNHTLQEQVTQLTEKLKN 586 Query: 268 SLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMT-ELTK 326 E K AQE S+E S E + +++ + ++ Sbjct: 587 QSESHKQAQENLHDQVQEQKAHLRAAQDRVLSLETSVNELNSQLNESKEKVSQLDIQIKA 646 Query: 327 KIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPW 386 K ELL +L+N L T + K + + + + + + Sbjct: 647 KTELLLSAEAAKTAQRADLQNHLDTAQNALQDKQQELNKITTQLDQVTAK--LQDKQEHC 704 Query: 387 SQLSSETLNQDTDKKIN-KNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGK 445 SQL S L + +K ++ + + +LE I+ L D + E S++ Sbjct: 705 SQLESH-LKEYKEKYLSLEQKTEELEGQIKKLEADSL--EVKASKEQALQDLQQQRQLNT 761 Query: 446 DTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELN--DEIKDVNVKDLIE 503 D + +L Q ME V + D+ + ++ E +KQ+L +E K + +D Sbjct: 762 DLELRATELSKQLEMEKEI---VSSTRLDLQKKSEALESIKQKLTKQEEEKQILKQDFET 818 Query: 504 KLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEE 563 + + Q +LN+ I + KVK + + ++ D SKVSDS K E+ Sbjct: 819 LSQETKIQHEELNNRIQTTVTELQKVKMEKEALMTELSTVKDKLSKVSDSLKNSKSEFEK 878 Query: 564 LHHLSQK-VAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQ 622 + + + +LE+ L+ L + E KK +E E A +LK L S Sbjct: 879 ENQKGKAAILDLEKTCKELKHQLQVQMENTLKEQKELKKSLEKEKEASHQLKLE--LNSM 936 Query: 623 KFDLVQELHILQQKYDEVEDKLADISQLQ--SDQVCSEIKSVHLEEQIDALSASKKELAL 680 + L+Q + L+Q E + +I++L+ S+Q +I+++ E +I L K EL Sbjct: 937 QEQLIQAQNTLKQNEKEEQQLQGNINELKQSSEQKKKQIEALQGELKIAVLQ--KTEL-- 992 Query: 681 VIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKIN 740 EN KL ++QL ++L +KE I + LQN +++ + +L+ + SELLA Sbjct: 993 --EN-KL-QQQLTQAAQELAAEKEKI-SVLQNNYEKSQETFKQLQSDFYGRESELLA--T 1045 Query: 741 HEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKAD 800 ++ ++ + + + DL I N +++ I L+ + A +E E++ Sbjct: 1046 RQDLKSVEEKLSL----AQEDL-ISN-RNQIGNQNKLIQELKTAKATLEQDSAKKEQQLQ 1099 Query: 801 QLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLE 860 + LQ+ QK E +++E ELVN + L + + + +Q EI N+EL+ ++ Sbjct: 1100 ERCKALQDIQK---EKSLKEKELVNEKSKLAEIEEIKCRQEKEITKLNEELKSHKLESIK 1156 Query: 861 ENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQ 920 E NL+ + + Q L KA+ A + + Q L+D ++ E + L Sbjct: 1157 EITNLKDAKQLLIQQKLELQGKADSLKAAVEQEKRNQQILKD------QVKKEEEEL--- 1207 Query: 921 KKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKN----IEYVTQLEAQLQEYKNNIENLNM 976 KKE IE ++ S I++K+V +K+E+N +T L L K ++ Sbjct: 1208 -KKEF----IEKEAKLHSEIKEKEVGMKKHEENEAKLTMQITALNENLGTVKKEWQSSQR 1262 Query: 977 NVEELNKMNLELIDKHVQKQQT--QSPDYTEQYINEINKLNALLKQKDEEIIALNQKINN 1034 V EL K +L + + T + D + K +++ +++ L +K++N Sbjct: 1263 RVSELEKQTDDLRGEIAVLEATVQNNQDERRALLERCLKGEGEIEKLQTKVLELQRKLDN 1322 Query: 1035 AQVSYMSMVSDYESKLAQFTTKLENMEEEMQRV 1067 + + + +S + T L E V Sbjct: 1323 TTAAVQELGRENQSLQIKHTQALNRKWAEDNEV 1355 Score = 104 bits (249), Expect = 2e-20 Identities = 201/1026 (19%), Positives = 439/1026 (42%), Gaps = 102/1026 (9%) Query: 146 HLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXX 205 ++ T+ +KD LQ ++ ET++ + +++EK EA K Sbjct: 334 NIQATLHQKDLDCQQLQSRLSASETSLHRIHVELSEKG---EATQK-LKEELSEVETKYQ 389 Query: 206 XXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEE-----ANKLL 260 + +QQ + +++ + +++E +LL+ L+E + KL+ Sbjct: 390 HLKAEFKQLQQQREEKEQHGLQLQSEINQLHSKLLETERQLGEAHGRLKEQRQLSSEKLM 449 Query: 261 EAAR--FEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEI----EEKG 314 + + ++ L+ S+L ++L++ +Q E +++ E + Sbjct: 450 DKEQQVADLQLKLSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQQSTTAKLREAQN 509 Query: 315 SLE--IANMTELTKKIELLEHL------NCQIRQTNKE-LENKLATMGTESKAVSSPSKK 365 LE + + + +KI+ LE L N + + +E L K+ E+ ++ +K Sbjct: 510 DLEQVLRQIGDKDQKIQNLEALLQKSKENISLLEKEREDLYAKIQAGEGETAVLNQLQEK 569 Query: 366 GSPLISR-----KSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKD 420 L + + +N + K L + Q + ++ + LE + LN Sbjct: 570 NHTLQEQVTQLTEKLKNQSESHKQAQENLHDQVQEQKAHLRAAQDRVLSLETSVNELNSQ 629 Query: 421 LVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAK 480 L + + +S+ D + + + Q H++ + + +++N+I Sbjct: 630 LNESKEKVSQLDIQIKAKTELLLSAEAAKTAQRADLQNHLD-TAQNALQDKQQELNKITT 688 Query: 481 VQEQLKQELNDEIK-----DVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKL 535 +Q+ +L D+ + + ++K+ EK S E++ +L +I + ++VK++ + Sbjct: 689 QLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQIKKLEADSLEVKASKEQ 748 Query: 536 KLKQMQK----------TIDNFSKVSDSNKEIVRLT--------EELHHLSQKVAELEEE 577 L+ +Q+ SK + KEIV T E L + QK+ + EEE Sbjct: 749 ALQDLQQQRQLNTDLELRATELSKQLEMEKEIVSSTRLDLQKKSEALESIKQKLTKQEEE 808 Query: 578 KGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKY 637 K Q+ D+++ + + + E+ N +T + + ++ +K L+ EL ++ K Sbjct: 809 K---QILKQDFET---LSQETKIQHEELNNRIQTTVTELQKVKMEKEALMTELSTVKDKL 862 Query: 638 DEVEDKLADI-SQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTI 696 +V D L + S+ + + + + LE+ L K +L + +EN ++++L Sbjct: 863 SKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKEL---KHQLQVQMENTLKEQKELK--- 916 Query: 697 KDLENDKE-DIMNKLQ-NYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGID 754 K LE +KE KL+ N +QE + K + ++ +L IN +QS Q + I+ Sbjct: 917 KSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQLQGNINELKQSSEQKKKQIE 976 Query: 755 AKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYS 814 A E + + +K + ++ + + +A +++ L+ ++ ++ Q S Sbjct: 977 ALQGELKIAVLQKTELENKLQQQLTQAAQELAAEKEKISVLQNNYEKSQETFKQLQ---S 1033 Query: 815 EYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQ 874 ++ +E EL LA D V EK L + E+ + +NQI NQN L + Sbjct: 1034 DFYGRESEL---LATRQDLKSVEEK--LSLAQEDL-ISNRNQI---GNQN---KLIQELK 1081 Query: 875 HYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKK--EIEDLEIEF 932 A +E+ D A+ E + Q + + L+ K + + + L+ +K K EIE+++ Sbjct: 1082 TAKATLEQ----DSAKKEQ-QLQERCKALQDIQKEKSLKEKELVNEKSKLAEIEEIKCRQ 1136 Query: 933 N---TQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQ-EYKNNIENLNMNVEELNKMNLEL 988 T++ ++ K+ + K N++ QL Q + E + ++L VE+ K N ++ Sbjct: 1137 EKEITKLNEELKSHKLESIKEITNLKDAKQLLIQQKLELQGKADSLKAAVEQ-EKRNQQI 1195 Query: 989 IDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYES 1048 + V+K++ + +++I + KL++ +K+K E+ + N A+++ ++ Sbjct: 1196 LKDQVKKEE---EELKKEFIEKEAKLHSEIKEK--EVGMKKHEENEAKLT--MQITALNE 1248 Query: 1049 KLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPK 1108 L + ++ + + + KQ D + L+ V+ D+ + L E L E I K Sbjct: 1249 NLGTVKKEWQSSQRRVSELEKQTDDLRGEIAVLEATVQNNQDERRALLERCLKGEGEIEK 1308 Query: 1109 TEGMII 1114 + ++ Sbjct: 1309 LQTKVL 1314 Score = 89.8 bits (213), Expect = 5e-16 Identities = 148/785 (18%), Positives = 332/785 (42%), Gaps = 64/785 (8%) Query: 146 HLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXX 205 +L + ++E+ L Q ++ +ET++ +L ++NE + + + Sbjct: 597 NLHDQVQEQKAHLRAAQDRVLSLETSVNELNSQLNESKEKVSQLDIQIKAKTELLLSAEA 656 Query: 206 XXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARF 265 D + + Q A++ + + E ++ ++ ++ +E LE+ Sbjct: 657 AKTAQRADLQNHLDTAQN---ALQ-DKQQELNKITTQLDQVTAKLQDKQEHCSQLESHLK 712 Query: 266 EISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELT 325 E ++ L Q+ E+ + K S E + ++ + + + TEL+ Sbjct: 713 EYKEKYLSLEQKTEELEGQIKKLEADSLEV-KASKEQALQDLQQQRQLNTDLELRATELS 771 Query: 326 KKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSP 385 K++E+ + + + T +L+ K S+A+ S +K L ++ + +K Sbjct: 772 KQLEMEKEI---VSSTRLDLQKK-------SEALESIKQK---LTKQEEEKQI---LKQD 815 Query: 386 WSQLSSETLNQDTDKKINKNEI-AKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXG 444 + LS ET KI E+ +++ + L K ++KE +++E T Sbjct: 816 FETLSQET-------KIQHEELNNRIQTTVTELQKVKMEKEALMTELSTVKDKLSKVSDS 868 Query: 445 KDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAK-VQEQLKQELNDEIKDVNVKDLIE 503 ++ + E+Q +G + I D+ + K ++ QL+ ++ + +K+ K+L + Sbjct: 869 LKNSKSEFEKENQ---KGKAAI------LDLEKTCKELKHQLQVQMENTLKE--QKELKK 917 Query: 504 KLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEE 563 L+ +E QL E+++ + +I+ ++ K K+ Q+ N +++ S+++ + E Sbjct: 918 SLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQLQGNINELKQSSEQKKKQIEA 977 Query: 564 LH-HLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQ 622 L L V + E + LQ L E + K+ ++N E + L+S Sbjct: 978 LQGELKIAVLQKTELENKLQQQLTQAAQELAAEKE---KISVLQNNYEKSQETFKQLQSD 1034 Query: 623 KFDLVQELHILQQKYDEVEDKLADISQ---LQSDQVCSEIKSVHLEEQIDAL---SASKK 676 + EL +Q VE+KL+ + +Q+ ++ K + + A ++KK Sbjct: 1035 FYGRESELLATRQDLKSVEEKLSLAQEDLISNRNQIGNQNKLIQELKTAKATLEQDSAKK 1094 Query: 677 ELALVIENLKLDKEQLYGTIKDLE--NDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISE 734 E L L Q ++K+ E N+K + + ++ ++T E++ + K+ Sbjct: 1095 EQQLQERCKALQDIQKEKSLKEKELVNEKSKLAEIEEIKCRQEKEITKLNEELKSHKLES 1154 Query: 735 L--LAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRR 792 + + + +Q IQ + + K +E + K ++ + EE + ++ Sbjct: 1155 IKEITNLKDAKQLLIQQKLELQGKADSLKAAVEQEKRNQQILKDQVKKEEEEL-----KK 1209 Query: 793 YSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQ 852 +E++A +L S ++EK+ ++ E +L ++ L ++ V+K+ + EL+ Sbjct: 1210 EFIEKEA-KLHSEIKEKEVGMKKHEENEAKLTMQITALNENLGTVKKEWQSSQRRVSELE 1268 Query: 853 KKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITH 912 K+ L E L+ ++ + Q AL+E+ + E E K QT++ +L+ L T Sbjct: 1269 KQTDDLRGEIAVLEATVQNNQDERRALLERCLK---GEGEIEKLQTKVLELQRKLDNTTA 1325 Query: 913 EHQTL 917 Q L Sbjct: 1326 AVQEL 1330 Score = 52.4 bits (120), Expect = 1e-04 Identities = 102/550 (18%), Positives = 220/550 (40%), Gaps = 50/550 (9%) Query: 1047 ESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEEL-QILVREQDDQIKELKETKLTFEMN 1105 ES LA + + +E+Q + L + K ++EEL + L + Q Q +E K L + + Sbjct: 75 ESNLALKRDDVTLLRQEVQDLQASLKEEKWYSEELKKELEKYQGLQQQEAKPDGLVTDSS 134 Query: 1106 --IPKTEGMIISSTIEPMS----DDANNVDXXXXXXXXXXXXLKVQEE----EEFIQERS 1155 + E + + E + D K EE E Q+ + Sbjct: 135 AELQSLEQQLEEAQTENFNIKQMKDLFEQKAAQLATEIADIKSKYDEERSLREAAEQKVT 194 Query: 1156 VLQEQSAKLNTELQECYTKIIQ-------------LETLNTELTGHDVVNQEQINQLKSK 1202 L E+ K T +Q+ T+++Q L + T + + + + +LK + Sbjct: 195 RLTEELNKEATVIQDLKTELLQRPGIEDVAVLKKELVQVQTLMDNMTLERERESEKLKDE 254 Query: 1203 LEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLS 1262 ++L ++ + +T+++LRS ++ + + EL Q L + + L L Sbjct: 255 CKKLQSQYASSEATISQLRSELAKGPQEVAVYVQEL--QKLKSSVNELTQKNQTLTENLL 312 Query: 1263 AFESKYEQLLDSVQSSTQEETNKIVTMEQ----VTSLQNKLQDKEEHLRNLQEKYADVIN 1318 E Y +L + + + N T+ Q LQ++L E L + + ++ Sbjct: 313 KKEQDYTKLEEKHNEESVSKKNIQATLHQKDLDCQQLQSRLSASETSLHRIHVELSEKGE 372 Query: 1319 QIEILRSEIEDEKVAFXXXXX------XXXXXXXXXXXDLRTE-NQSYKQMQEQSILNIN 1371 + L+ E+ + + + L++E NQ + ++ E + Sbjct: 373 ATQKLKEELSEVETKYQHLKAEFKQLQQQREEKEQHGLQLQSEINQLHSKLLETE-RQLG 431 Query: 1372 EENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRN 1431 E + +LK+ +V D + K+ L QL+ K + + H+ T Q Sbjct: 432 EAHGRLKEQRQLSSEKLMDKEQQVADLQLKLSRLEEQLKEKVTNSTELQHQLDKTKQQHQ 491 Query: 1432 DE---FENVRQQLVEYEKRIEDLTY---EKESELAILRLKMHENANHYETMQKESEIERV 1485 ++ ++ +L E + +E + +K+ ++ L + ++ + ++KE E Sbjct: 492 EQQALQQSTTAKLREAQNDLEQVLRQIGDKDQKIQNLEALLQKSKENISLLEKERE---- 547 Query: 1486 KLIEELNVKITESVSLNKQVAELNKALEEEVAK-TNEMQTALENQEIEIVTLNDEITNLQ 1544 L ++ E+ LN Q+ E N L+E+V + T +++ E+ + L+D++ + Sbjct: 548 DLYAKIQAGEGETAVLN-QLQEKNHTLQEQVTQLTEKLKNQSESHKQAQENLHDQVQEQK 606 Query: 1545 NMVRASSSKI 1554 +RA+ ++ Sbjct: 607 AHLRAAQDRV 616 >UniRef50_Q09EF7 Cluster: Putative uncharacterized protein; n=8; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 1911 Score = 131 bits (316), Expect = 2e-28 Identities = 245/1223 (20%), Positives = 511/1223 (41%), Gaps = 112/1223 (9%) Query: 455 EHQQHMEGPSLI-HVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQIT 513 ++ +H P ++ H + D+ V E+ EL ++K+ K+ L+ E + Sbjct: 93 DYGRHRSSPRVLAHYNLDGADIG----VGEENLDELFAKLKEELFKN--NTLEEVNEMLR 146 Query: 514 QLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAE 573 + ND AAN+++ +N +L+Q+Q+ S S R E H +K+ Sbjct: 147 EENDAALAANEHLRVDATNLSRQLQQLQQQQHTESMRFRSENTRYRNQTETQH--RKLIS 204 Query: 574 LEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHIL 633 L +E ++ L ++ +D+ +++ E A KAI E + D Q+ + Sbjct: 205 LWKEFTAVKRQL--HELRTTTANDLDRQLTEFTRCATLMRKAIRHAEQKNLD--QKEQMK 260 Query: 634 QQKYDEVEDKLADISQLQSDQVCSEIKS-------VHLEEQIDALSASKKELALVIENLK 686 ++K D +++ L ++ + + + SE K+ E++ L EL+ ++E L Sbjct: 261 REKDDVLDETLRQLNSVTENYMKSEEKANERQRDLKRKEDECRKLREQNDELSDILEQLS 320 Query: 687 LDKEQLYGTIKDLENDKEDIMNKLQNYI-QENMDLTDKLEKMSAEKISELLAKINHEEQS 745 ++ G + D+ K++ + +N ++ + E + AK + E++ Sbjct: 321 KMAHEMAGG-RGRNETPMDVARKMRKLLTTKNGEIDESREAAKQAEKERDRAKKDLEKEE 379 Query: 746 KIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSY 805 K + + +A+ + +Y + E +L K + + E I +E++R S E+ + + Sbjct: 380 K-RRKDDREAERKRSSVYSQR-EHDLKKLDDELRKASEKIRNLEEQRESQEKLTISVQNS 437 Query: 806 LQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHE-----NKELQKKNQILLE 860 L E + + ++ E+ ++ L + + E+ L + E KE ++ +I E Sbjct: 438 LNEAHRQHKQFI--EELMIRHREELKEREDSHEEALRSKDTEERSRFEKERSEREKIRRE 495 Query: 861 --ENQNLQISL-SDMQQHYNALVEKANRTDLAESE----STKYQTQLRDLESNLKRITHE 913 E + Q SL D+ L +K R D+ E+E K +T+ + I Sbjct: 496 SDELRETQRSLKGDVAAMKTDLDDKTLRLDMLETERDELKKKLETEREQADQRDLEIAEC 555 Query: 914 HQTL--IVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNI 971 L + +K+ E+ EF I + + K+ E++ ++ + L Q++ + + Sbjct: 556 RAKLDEMAEKEAELRKELAEFQAIITAMEGEGKLNQEQFLESKNELNTLTDQIESLNSEV 615 Query: 972 ENLNMNVEELNKMNLELIDKHVQKQQTQSPDYT---EQYINEINKLNALLKQKDEEIIAL 1028 EN N + L L+ + H+Q +T S T E+ EI+ L A L + E++ Sbjct: 616 ENKNEEIRNL-MATLQEKEVHIQNVRTSSHQLTATYEEANGEIDILKAELTRLHEQVNER 674 Query: 1029 NQKINNAQVSYMSMVSDYESKLAQFTT---KLENMEEEMQRVSKQLLDSKQHNEELQILV 1085 ++I+ A Y ++ L T K E ++ E++ ++++ + ++ +L+ L+ Sbjct: 675 TRQISEANEKYDDAARKNDALLEDVATWQEKYEQLKMELEEMNRRGQEKEREEADLRALL 734 Query: 1086 REQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMS---DDANNVDXXXXXXXXXXXXL 1142 D ++ KLT E+ K +G+ + S E +S + N + L Sbjct: 735 ----DDLRG-NFDKLTNEL---KQKGVTVDSLNEEISSLKEQLNKSEKERKEELLRMEEL 786 Query: 1143 KVQEEEEFIQERSVLQEQSAKLNTELQ----ECYTKIIQLETLNTEL-TGHDVV------ 1191 + + E E +E V + + K ++ EC ++ +L ++ L HD + Sbjct: 787 EQKNEAEMKEEYEVKLQLAEKDRQGVENFGKECEARMNELTKIHEMLMEEHDQLKVDHLH 846 Query: 1192 NQEQINQLKSK----LEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQRE 1247 +E++ +LK K LE+LN +ND + + R+ + S+ ++ E+ E Q L Sbjct: 847 TEEEVERLKEKMRKELEKLNEQNDGDRAEWSNERNRLESSKNEAVTELQER-VQKLEDVV 905 Query: 1248 ADFQKTEHELRVQLSAFESKYEQLLDSVQSS--TQEETNKIVTMEQVTSLQN--KLQDKE 1303 + + E LR L K L D ++ T EE + EQ T + KL +++ Sbjct: 906 KEKEDKEIALRRDLEDSHEKSRDLDDKLRKMELTDEEKEEDRKKEQKTLNEERMKLMEQK 965 Query: 1304 EHLRNLQEKYADVINQ----IEILRSEIEDEKVAFX---XXXXXXXXXXXXXXXDLRTEN 1356 E + K+A I+Q I +L ++E L T Sbjct: 966 EEAMLVATKHATTIDQQTRRISVLEGDVEKLTAGIAERESSINALESNTMELISKLETTE 1025 Query: 1357 QSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLE---LTHQLELKD 1413 ++++++ + + ++N++LK ++ D ++ E + H + +K+ Sbjct: 1026 AELEKLKDELAVML-KQNSELKNGKEGLSEKWNEERKKIQDLADQLREANKVVHNMRMKN 1084 Query: 1414 SEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIE---DLTYEKESEL-AILRLKMHE- 1468 + +K +E +T ++ + QL++ + E DL + E + ++L+ +E Sbjct: 1085 VNLEEKKNELDQNVTDLTNKVRQLEIQLMDKAAKNEVSGDLLRKMEHDAQSMLKQAQNEQ 1144 Query: 1469 -NANHYETMQKESEIERVKLIEEL-NVKITESVSLNKQVAELNKALE-----EEVAKTNE 1521 E ++K + E +L+ +L VK V + ++ L+ EE A E Sbjct: 1145 FRLTDLEKVRKALQDENQRLVNDLATVKAAFEVKRETSKSAISDILDKYRSAEEKANKGE 1204 Query: 1522 MQTALENQEIEIVTLNDEITNLQ-----NMVRASSSKIQKHVSFASDTKQGRDEQLDNTM 1576 + ++ VTL E L+ N +R S + ++ S ++ ++ E L N M Sbjct: 1205 LDNQRLRSDLATVTLKLERQELKAKDSDNRLRDSQKRFEEVQSKLANLQKSAVESLQNPM 1264 Query: 1577 ------NKELLDAVPRAELDLAM 1593 N+ + +PRA + + Sbjct: 1265 SSNSRQNRSIYVDIPRAASSIGL 1287 Score = 113 bits (271), Expect = 5e-23 Identities = 277/1504 (18%), Positives = 606/1504 (40%), Gaps = 126/1504 (8%) Query: 140 QLGDVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXX 199 QL VT N +K ++ A + Q +K E L+E+ +E I+E +K Sbjct: 273 QLNSVTE--NYMKSEEKA-NERQRDLKRKEDECRKLREQNDELSDILEQLSKMAHEMAGG 329 Query: 200 XXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQR--LLKDIESKDVRISSLEEAN 257 + K TK E + EA + EK+R KD+E ++ R EA Sbjct: 330 RGRNETPMDVARKMRKLLTTKNGEIDESREAAKQAEKERDRAKKDLEKEEKRRKDDREAE 389 Query: 258 KLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLE 317 + + + + KL EL + A + I + EE+ E +EK ++ Sbjct: 390 RKRSSVYSQREHDLKKLDDELRK---------------ASEKIR-NLEEQRESQEKLTIS 433 Query: 318 IAN-MTELTKKI-ELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSG 375 + N + E ++ + +E L + R+ KE E+ SK S+ R+ Sbjct: 434 VQNSLNEAHRQHKQFIEELMIRHREELKEREDSHEE-ALRSKDTEERSRFEKERSEREKI 492 Query: 376 RNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXX 435 R + +++ L + TD + LE L K L + ++D Sbjct: 493 RRESDELRETQRSLKGDVAAMKTDLDDKTLRLDMLETERDELKKKLETEREQADQRDLEI 552 Query: 436 XXXXXXXXGKDTLIAQLQLEHQQH------MEGPSLIHVGTNTEDVNEIAKVQEQLKQEL 489 A+L+ E + MEG ++ E NE+ + +Q+ + L Sbjct: 553 AECRAKLDEMAEKEAELRKELAEFQAIITAMEGEGKLNQEQFLESKNELNTLTDQI-ESL 611 Query: 490 NDEIKDVN--VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNF 547 N E+++ N +++L+ L+ E I N + ++N ++ + + + T + Sbjct: 612 NSEVENKNEEIRNLMATLQEKEVHIQ--NVRTSSHQLTATYEEANGEIDILKAELTRLH- 668 Query: 548 SKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMEN 607 +V++ ++I E+ ++K L E+ Q Y+ +M ++ ++ E E Sbjct: 669 EQVNERTRQISEANEKYDDAARKNDALLEDVATWQ---EKYEQLKMELEEMNRRGQEKER 725 Query: 608 LAETRLKAISLLESQKFD-LVQELHILQQKYDEVEDKLADIS-QLQSDQVCSEIKSVHLE 665 E L+A+ FD L EL D + ++++ + QL + + + + +E Sbjct: 726 -EEADLRALLDDLRGNFDKLTNELKQKGVTVDSLNEEISSLKEQLNKSEKERKEELLRME 784 Query: 666 EQIDALSAS-KKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKL 724 E A K+E + ++ + D++ + K+ E ++ K+ + E D Sbjct: 785 ELEQKNEAEMKEEYEVKLQLAEKDRQGVENFGKECEARMNEL-TKIHEMLMEEHDQLKVD 843 Query: 725 EKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESE-LSKYKSRICRLEE 783 + E++ L K+ E + + G A+ +E+ ++E +++ + R+ +LE+ Sbjct: 844 HLHTEEEVERLKEKMRKELEKLNEQNDGDRAEWSNERNRLESSKNEAVTELQERVQKLED 903 Query: 784 SIAVMEDRRYSLERKAD---QLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQ 840 + ED+ +L R + + L +K + +++E + ++ +R+ + Sbjct: 904 VVKEKEDKEIALRRDLEDSHEKSRDLDDKLRKMELTDEEKEEDRKKEQKTLNEERM---K 960 Query: 841 LLEIEHENKELQKKNQILLEEN-QNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQ 899 L+E + E + K+ +++ + + + D+++ + E+ + + ES + + ++ Sbjct: 961 LMEQKEEAMLVATKHATTIDQQTRRISVLEGDVEKLTAGIAERESSINALESNTMELISK 1020 Query: 900 LRDLESNLKRITHEHQTLIVQK---KKEIEDLEIEFNTQ------IESAIRD-KKVLNEK 949 L E+ L+++ E ++ Q K E L ++N + + +R+ KV++ Sbjct: 1021 LETTEAELEKLKDELAVMLKQNSELKNGKEGLSEKWNEERKKIQDLADQLREANKVVHNM 1080 Query: 950 YEKNI---EYVTQLEAQLQEYKNNIENLNMNVEEL---NKMNLELIDKHVQKQQTQSPD- 1002 KN+ E +L+ + + N + L + + + N+++ +L+ K Q+ Sbjct: 1081 RMKNVNLEEKKNELDQNVTDLTNKVRQLEIQLMDKAAKNEVSGDLLRKMEHDAQSMLKQA 1140 Query: 1003 YTEQY-INEINKLNALLKQKDEEII----ALNQKINNAQVSYMSMVSDYESKLAQFTTKL 1057 EQ+ + ++ K+ L+ +++ ++ + + + S +SD K K Sbjct: 1141 QNEQFRLTDLEKVRKALQDENQRLVNDLATVKAAFEVKRETSKSAISDILDKYRSAEEKA 1200 Query: 1058 ENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISST 1117 E + QR+ L E ++ ++ D+++++ ++ + + + + S Sbjct: 1201 NKGELDNQRLRSDLATVTLKLERQELKAKDSDNRLRDSQKRFEEVQSKLANLQKSAVESL 1260 Query: 1118 IEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQ 1177 PMS ++ + + E + + RS + A + +Q + Sbjct: 1261 QNPMSSNSRQNRSIYVDIPRAASSIGLNENSDEVPLRSSPSVRFADSSQNMQRAVDSMDV 1320 Query: 1178 LETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAE 1237 ++ L LK ++EQL +N A+L ++ A D E+ + Sbjct: 1321 SSSVGVTL-----------RFLKERIEQLEADN-------ADLSDALEKAKD----ELRQ 1358 Query: 1238 LWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSS--TQEETNKIVTMEQVTSL 1295 + LA R+ ++ E +L V ++ + E + S + T EE+++ E + S+ Sbjct: 1359 R-NEKLADRQMVIERVERQL-VHITEERNTIENRMTSQRQMYLTNEESSRSREHE-IRSM 1415 Query: 1296 QNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTE 1355 + ++ E HLR + K A + +IE+L ++ D + DL + Sbjct: 1416 KARISTLELHLREKESKLAHLRKEIEVLHGQLHD-ALESKEKATGLVGVQDSKHRDLEEQ 1474 Query: 1356 NQSYKQMQEQSI---LNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELK 1412 + +E +I EN L + + D E ++ E ++ L+ Sbjct: 1475 LDRANRERELAIGKQRRTLAENENLFRKLEQLEKEREQLMREITD-ERRLNE-RNRTSLE 1532 Query: 1413 DSEIYQKTHEYTITLTQR-NDEFENVRQQLVEYEKRIEDLTYEKES---ELAILRLKMHE 1468 + + ++T + +T ++ +E E Q+ +E+ ++T + E LR++M + Sbjct: 1533 ELRVSERTWKSAMTTAKKPAEEQERAVQEQRRWEESNHEMTNRNTALTKECDRLRVEMRD 1592 Query: 1469 NANHYETMQKESEIERVKLIEELNVKI---TESVSLNKQVAELNKALEEE-------VAK 1518 N + S ++ + EEL+ K+ +V+ K+ E K LE E + K Sbjct: 1593 QLNRMNGINLRS-VDFERKNEELSSKLIVMQNTVTAMKKFEEEWKRLEAEMRAELKILRK 1651 Query: 1519 TNEMQTA----LENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDN 1574 MQTA L+ + T EI ++ + S +++HV + K ++ + Sbjct: 1652 EKLMQTAEIEDLKRKSFRSDTEKKEIEGIRVRLEREISALKRHVDALEEEKGKTEKAVRE 1711 Query: 1575 TMNK 1578 TMN+ Sbjct: 1712 TMNE 1715 Score = 96.7 bits (230), Expect = 5e-18 Identities = 222/1224 (18%), Positives = 499/1224 (40%), Gaps = 95/1224 (7%) Query: 147 LSNTIKEKDNALSVLQVKMKIMETTILDLQEKI---NEKDQIIEAKNKATTXXXXXXXXX 203 L+ T +E + + +L+ ++ + + + +I NEK KN A Sbjct: 646 LTATYEEANGEIDILKAELTRLHEQVNERTRQISEANEKYDDAARKNDALLEDVATWQEK 705 Query: 204 XXXXXXXXEDTK---QQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLL 260 E+ Q+ + + + A+ + + +L +++ K V + SL E L Sbjct: 706 YEQLKMELEEMNRRGQEKEREEADLRALLDDLRGNFDKLTNELKQKGVTVDSLNEEISSL 765 Query: 261 EAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIAN 320 + + E + +E+ + Q E +++ +E G A Sbjct: 766 KEQLNKSEKERKEELLRMEELEQKNEAEMKEEYEVKLQLAE---KDRQGVENFGKECEAR 822 Query: 321 MTELTKKIELLEHLNCQIR----QTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGR 376 M ELTK E+L + Q++ T +E+E M E + ++ + S + R Sbjct: 823 MNELTKIHEMLMEEHDQLKVDHLHTEEEVERLKEKMRKELEKLNEQNDGDRAEWSNERNR 882 Query: 377 NTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXX 436 +SK ++ +D K+ EIA L ++ ++ D + + + + Sbjct: 883 LESSKNEAVTELQERVQKLEDVVKEKEDKEIA-LRRDLEDSHEKSRDLDDKLRKMELTDE 941 Query: 437 XXXXXXXGKDTLIAQLQLEHQQHMEGPSLI---HVGTNTEDVNEIAKVQ---EQL----- 485 + + + +++ + E L+ H T + I+ ++ E+L Sbjct: 942 EKEEDRKKEQKTLNEERMKLMEQKEEAMLVATKHATTIDQQTRRISVLEGDVEKLTAGIA 1001 Query: 486 KQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHK---LKLKQMQK 542 ++E + + N +LI KL++ E ++ +L DE+ K ++K+ + K + +K Sbjct: 1002 ERESSINALESNTMELISKLETTEAELEKLKDELAVMLKQNSELKNGKEGLSEKWNEERK 1061 Query: 543 TIDNFS-KVSDSNKEI-------VRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMI 594 I + + ++ ++NK + V L E+ + L Q V +L + L++ L+D + + Sbjct: 1062 KIQDLADQLREANKVVHNMRMKNVNLEEKKNELDQNVTDLTNKVRQLEIQLMDKAAKNEV 1121 Query: 595 ESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQ 654 D+ +KM E+ A++ LK + + DL + LQ + + + LA + + + Sbjct: 1122 SGDLLRKM---EHDAQSMLKQAQNEQFRLTDLEKVRKALQDENQRLVNDLATVKA--AFE 1176 Query: 655 VCSEIKSVHLEEQIDAL-SASKKELALVIENLKLDKEQLYGTIKDLENDK---EDIMNKL 710 V E + + +D SA +K ++N +L + T+K LE + +D N+L Sbjct: 1177 VKRETSKSAISDILDKYRSAEEKANKGELDNQRLRSDLATVTLK-LERQELKAKDSDNRL 1235 Query: 711 QNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESE 770 ++ + ++ KL + + L ++ S+ +D + + E Sbjct: 1236 RDSQKRFEEVQSKLANLQKSAVESLQNPMS--SNSRQNRSIYVDIPRAASSIGLNENSDE 1293 Query: 771 LSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVL 830 + S R +S M+ S++ + +G L+ ++ + +L + L Sbjct: 1294 VPLRSSPSVRFADSSQNMQRAVDSMD-VSSSVGVTLRFLKERIEQLEADNADLSDALEKA 1352 Query: 831 MDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAE 890 D R ++L + + + ++++ + EE ++ ++ +Q Y E+++R+ E Sbjct: 1353 KDELRQRNEKLADRQMVIERVERQLVHITEERNTIENRMTSQRQMY-LTNEESSRS--RE 1409 Query: 891 SESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKY 950 E + ++ LE +L+ E ++ + +KEIE L + + +ES + ++ + Sbjct: 1410 HEIRSMKARISTLELHLR----EKESKLAHLRKEIEVLHGQLHDALESKEKATGLVGVQD 1465 Query: 951 EKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINE 1010 K+ + QL+ +E + I + E + +L +++Q E+ +NE Sbjct: 1466 SKHRDLEEQLDRANRERELAIGKQRRTLAENENLFRKLEQLEKEREQLMREITDERRLNE 1525 Query: 1011 INKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQ 1070 N+ + E + ++++ + ++ ++ + + Q + E EM + Sbjct: 1526 RNRTSL-------EELRVSERTWKSAMTTAKKPAEEQERAVQEQRRWEESNHEMTNRNTA 1578 Query: 1071 LLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDX 1130 L + + L++ +R+Q +++ + + FE K E +SS + M + + Sbjct: 1579 L---TKECDRLRVEMRDQLNRMNGINLRSVDFER---KNEE--LSSKLIVMQNTVTAMKK 1630 Query: 1131 XXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDV 1190 + E E E +L+++ E+++ K + +T E+ G V Sbjct: 1631 FEEEWK--------RLEAEMRAELKILRKEKLMQTAEIEDLKRKSFRSDTEKKEIEGIRV 1682 Query: 1191 VNQEQINQLKSKLEQLNTENDNLLSTVAEL---RSSISSAVDQRGFEIAELWKQHLAQRE 1247 + +I+ LK ++ L E V E R +I ++ E +L++ + AQ + Sbjct: 1683 RLEREISALKRHVDALEEEKGKTEKAVRETMNERRAIDKSLASMERENQQLYR-NCAQLQ 1741 Query: 1248 ADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLR 1307 A Q E + + +K LL++ ++ EE Q+ S+ ++ H R Sbjct: 1742 AQIQNLERDAGNRSVTKLAKEHSLLEARIAALIEE------KRQLQSMLDQKDANYSHKR 1795 Query: 1308 NLQEKYADVINQIEILRSEIEDEK 1331 L E +QI++LR ++E E+ Sbjct: 1796 KLLE------SQIQLLREQLEAER 1813 Score = 95.1 bits (226), Expect = 1e-17 Identities = 259/1343 (19%), Positives = 542/1343 (40%), Gaps = 133/1343 (9%) Query: 297 KQSIEPSCEEKTEIEEKGSLEIANM-TELTKKIELLEHLNCQIRQTNKELENKLATMGTE 355 ++ I +E E + ++A M T+L K L+ L + + K+LE + Sbjct: 489 REKIRRESDELRETQRSLKGDVAAMKTDLDDKTLRLDMLETERDELKKKLETEREQADQR 548 Query: 356 SKAVSSPSKKGSPLISRKSG-RNTASKMKSPWSQLSSE-TLNQDTDKKINKNEIAKLEMV 413 ++ K + +++ R ++ ++ + + E LNQ+ + +KNE+ L Sbjct: 549 DLEIAECRAKLDEMAEKEAELRKELAEFQAIITAMEGEGKLNQEQFLE-SKNELNTLTDQ 607 Query: 414 IQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNT- 472 I+SLN ++ +K I T QL +++ ++ Sbjct: 608 IESLNSEVENKNEEIRNLMATLQEKEVHIQNVRTSSHQLTATYEEANGEIDILKAELTRL 667 Query: 473 -EDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKS 531 E VNE + + ++ +D + + L+E + + +E+ QL E++ N+ + K Sbjct: 668 HEQVNERTRQISEANEKYDDAARKNDA--LLEDVATWQEKYEQLKMELEEMNRRG-QEKE 724 Query: 532 NHKLKLKQMQKTI-DNFSKVSDSNKE----IVRLTEELHHLSQKVAELEEEKGNLQLHLV 586 + L+ + + NF K+++ K+ + L EE+ L +++ + E+E+ L + Sbjct: 725 REEADLRALLDDLRGNFDKLTNELKQKGVTVDSLNEEISSLKEQLNKSEKERKEELLRME 784 Query: 587 DYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLAD 646 + + K EM+ E +L+ L E + + + + +E+ K+ + Sbjct: 785 ELEQ---------KNEAEMKEEYEVKLQ---LAEKDRQGVENFGKECEARMNELT-KIHE 831 Query: 647 ISQLQSDQVCSEIKSVHLEEQIDALSAS-KKELALVIENLKLDKEQLYGTIKDLENDKED 705 + + DQ+ ++ +H EE+++ L +KEL + E D+ + LE+ K + Sbjct: 832 MLMEEHDQL--KVDHLHTEEEVERLKEKMRKELEKLNEQNDGDRAEWSNERNRLESSKNE 889 Query: 706 IMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIE 765 + +LQ +Q KLE + EK + +A E S +++ +D K+++ +L E Sbjct: 890 AVTELQERVQ-------KLEDVVKEKEDKEIALRRDLEDSHEKSR-DLDDKLRKMELTDE 941 Query: 766 NIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVN 825 E + K + + EE + +ME + ++ A + + + ++ + S ++L Sbjct: 942 EKEEDRKKEQKTLN--EERMKLMEQKEEAM-LVATKHATTIDQQTRRISVLEGDVEKLTA 998 Query: 826 RLAVLMDHDRVVEKQLLEI-------EHENKELQKKNQILLEENQNLQISLSDMQQHYNA 878 +A +E +E+ E E ++L+ + ++L++N L+ + + +N Sbjct: 999 GIAERESSINALESNTMELISKLETTEAELEKLKDELAVMLKQNSELKNGKEGLSEKWNE 1058 Query: 879 LVEKANRTDLAES--ESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQI 936 E+ DLA+ E+ K +R NL+ +E + ++ LEI+ Sbjct: 1059 --ERKKIQDLADQLREANKVVHNMRMKNVNLEEKKNELDQNVTDLTNKVRQLEIQ----- 1111 Query: 937 ESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQ 996 + DK NE + + + ++E Q +N + +L K+ L D++ Q Sbjct: 1112 ---LMDKAAKNEV---SGDLLRKMEHDAQSMLKQAQNEQFRLTDLEKVRKALQDEN---Q 1162 Query: 997 QTQSPDYTEQYINEINKLNALLKQKD--EEIIALNQKINNAQVSYMSMVSDYESKLAQFT 1054 + + T + E+ + + D ++ + +K N ++ + SD LA T Sbjct: 1163 RLVNDLATVKAAFEVKRETSKSAISDILDKYRSAEEKANKGELDNQRLRSD----LATVT 1218 Query: 1055 TKLENMEEEMQRVSKQLLDSKQHNEELQI-LVREQDDQIKELKET-------KLTFEMNI 1106 KLE E + + +L DS++ EE+Q L Q ++ L+ + ++I Sbjct: 1219 LKLERQELKAKDSDNRLRDSQKRFEEVQSKLANLQKSAVESLQNPMSSNSRQNRSIYVDI 1278 Query: 1107 PKTE---GMIISSTIEPMSDD-----ANNVDXXXXXXXXXXXXLKVQEEEEFIQER-SVL 1157 P+ G+ +S P+ A++ V F++ER L Sbjct: 1279 PRAASSIGLNENSDEVPLRSSPSVRFADSSQNMQRAVDSMDVSSSVGVTLRFLKERIEQL 1338 Query: 1158 QEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTV 1217 + +A L+ L++ ++ Q N +L +V + QL E+ NT +N +++ Sbjct: 1339 EADNADLSDALEKAKDELRQR---NEKLADRQMVIERVERQLVHITEERNTI-ENRMTSQ 1394 Query: 1218 AELRSSISSAVDQRGFEIAELWKQ------HLAQREADFQKTEHELRV---QL-SAFESK 1267 ++ + + R EI + + HL ++E+ E+ V QL A ESK Sbjct: 1395 RQMYLTNEESSRSREHEIRSMKARISTLELHLREKESKLAHLRKEIEVLHGQLHDALESK 1454 Query: 1268 YEQL-LDSVQSSTQEETNKIV----------------TMEQVTSLQNKLQDKEEHLRNLQ 1310 + L VQ S + + + T+ + +L KL+ E+ L Sbjct: 1455 EKATGLVGVQDSKHRDLEEQLDRANRERELAIGKQRRTLAENENLFRKLEQLEKEREQLM 1514 Query: 1311 EKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNI 1370 + D E R+ +E+ +V+ R + ++ E+S + Sbjct: 1515 REITDERRLNERNRTSLEELRVSERTWKSAMTTAKKPAEEQERAVQE--QRRWEESNHEM 1572 Query: 1371 NEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQR 1430 N L K R+N + ++ E K+ E+ K T+T Sbjct: 1573 TNRNTALTKECDRLRVEMRDQLNRMNGINLRSVDF----ERKNEELSSKLIVMQNTVTAM 1628 Query: 1431 NDEFENVRQQLVEYEKRIEDLTYEKESELAILRLK-MHENANHYETMQKESEIERVKLIE 1489 +FE ++L E E R E KE + ++ + + +T +KE E RV+L Sbjct: 1629 K-KFEEEWKRL-EAEMRAELKILRKEKLMQTAEIEDLKRKSFRSDTEKKEIEGIRVRLER 1686 Query: 1490 ELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRA 1549 E++ +L ++ + KA+ E + + + +L + E E N ++ ++A Sbjct: 1687 EISALKRHVDALEEEKGKTEKAVRETMNERRAIDKSLASMERE----NQQLYRNCAQLQA 1742 Query: 1550 SSSKIQKHVSFASDTKQGRDEQL 1572 +++ S TK ++ L Sbjct: 1743 QIQNLERDAGNRSVTKLAKEHSL 1765 >UniRef50_A0CGX1 Cluster: Chromosome undetermined scaffold_18, whole genome shotgun sequence; n=3; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_18, whole genome shotgun sequence - Paramecium tetraurelia Length = 2941 Score = 131 bits (316), Expect = 2e-28 Identities = 253/1404 (18%), Positives = 591/1404 (42%), Gaps = 129/1404 (9%) Query: 217 QMTKMQENFIAMEAEWK-DEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLA 275 ++ K+QEN +E E + +++++ K +++ ++ L++A +++ LE K Sbjct: 418 KVRKVQENTNRLENEKQINQEEQFWKQKYEEEIE---KQKRGYSLDSAEYQL-LEQIKEN 473 Query: 276 QELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLN 335 QEL + ++ E ++ E + + L +I+ L+ N Sbjct: 474 QELLSQINLMKNDFLQQELYNEMELKKKQAENNKLMEMQDQQEQQQSFLNFQIKDLQQKN 533 Query: 336 CQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLN 395 + + ++L KL E + + + + + + + N ++ P ++ Sbjct: 534 LENEKVKQDLLIKLQQNDKEMQRLKNTINQSN--LKPQQQDNYQIQLCEPLLIEKNKKQL 591 Query: 396 QDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTL-IAQLQL 454 + D+ +KN + E +I+ +D ++K Y S K + + I+QL+ Sbjct: 592 ESEDQLKDKN-LELQEKIIEL--QDELNKIYSESTKTRRNFTQKEIVDPEKAIRISQLEQ 648 Query: 455 EHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQ 514 E+Q+ + +++ ++E ++ + + I V DLI + + +E Sbjct: 649 ENQK-------LQAQIKEKELQRKDDLKE-FQEMIGNGITQQKVVDLIAEKQKLQEHFRV 700 Query: 515 LNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSN--KEIVRLTEELHHLSQKVA 572 L +++DA +N I+++S + K K++ K ++ F + + + L +++++L ++ Sbjct: 701 LQNKVDALQQNQIRLQSELQSKNKEL-KELEQFQGEQNQPYIQGQINLNDQINNLEAQLI 759 Query: 573 ELEEEKGNLQLHLVDYDSGRMIESDVYKKMI-------EMENLAETRLKAISLLESQKFD 625 +++ L S ++ + ++ ++ NL+ + I +LE Q Sbjct: 760 LAKKQYQELLETSQQNSSPNGLKEKILQQQALIHDYENQINNLSNKIEQEIPILEGQLAT 819 Query: 626 LVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENL 685 Q++ + + E + ++ L + Q + + + L+ +EL L L Sbjct: 820 ANQQIQVAENDILNQEKRYNEL--LNNKQYLQNPDTQIPSDDLKKLTEKNQELNL---QL 874 Query: 686 KLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKIN---HE 742 + + +L + E KE+I K + Y +L +++++ ++I + KIN + Sbjct: 875 QQNNRKLEVQLDIEEKLKEEISEKDREY-----NLAQQIQQIQQDQIKDQQQKINKMIDK 929 Query: 743 EQSKIQTQFGIDAKI-QERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQ 801 EQ +Q + +KI Q+RD+ ++N + + K I +++E + ++ ++ E Sbjct: 930 EQQLMQEIANLSSKINQQRDINVDNTKQDNQNNKDDIIQIQEDDSALKIKQLQEELNKVI 989 Query: 802 LGSYLQEKQ-KAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKN--QIL 858 + L+ + + + + +EL + L ++ Q+ +E Q+ N Q+ Sbjct: 990 NENVLKNNECQVLQKLKPENEELRAQQTQLYYQIVQLQNQIHNLESFKPSKQQDNDQQLT 1049 Query: 859 LEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLI 918 E + +++S +QQ L R L E ++ + + + E N +H + Sbjct: 1050 FETDPEKTLAISQLQQQIQQL-----RNQLQEIQNQRAEDLQKFKEINENGADQQHIIEL 1104 Query: 919 VQKKKEIEDLEIEFNTQIESAIRDKKVL-NEKYEKNIEYVTQLEAQLQE-YKNNIENLNM 976 Q K+ +E Q+++A++++ ++ + +KN ++ +E +K +ENLN Sbjct: 1105 FQSKQNLEQQLRNLQNQLDNALQEQILIQGQLIQKNKQFSEFCSNYNEEDFKKQLENLNQ 1164 Query: 977 NVEELNKMNLELIDKHVQKQQTQSPDYTEQYINE--INKLNALLKQKDEEIIALNQKINN 1034 ++E + L+ ++ + + S + T E + + N + +Q+ +EI ++Q+++N Sbjct: 1165 IIQEQQEKLLQSKQQYQELLELTSQNLTPNGQKEKLLQQANQIHEQQ-QEIQLMHQQLDN 1223 Query: 1035 AQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKE 1094 +++Y+ K T++ + E Q + Q Q N+ + + Sbjct: 1224 EVPKLQGALAEYKQKYNDSQTEIHLLMERYQNLLNQRSKQDQSND------KSFSTKNNN 1277 Query: 1095 LKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQER 1154 L++T L+ + K + + I DD N + +QE QE Sbjct: 1278 LQDTNLSAQKYDDKND----QTNISDFQDDINRKNI-------------LQE-----QEI 1315 Query: 1155 SVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTE--NDN 1212 +++ +Q K ++EL++ + +I + ++I LK+KL + NTE + Sbjct: 1316 ALMHKQQEKFSSELEDLHKQI--------------SLKDQEILILKNKLAEGNTEFWKEE 1361 Query: 1213 LLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLL 1272 + + SI + +I + +Q+L D Q+ +L Q++ E++ ++ L Sbjct: 1362 YTKLATQNKGSIKT-------QIQDSPEQYLI---VDLQQQSQKLINQIAEIEAERQEDL 1411 Query: 1273 DSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKV 1332 Q + + K ++ Q+ S +LQ + R +Q + D++ Q++ + +++D K+ Sbjct: 1412 RKFQKILENDGTKDNSVVQLFSENQQLQQSK---RQMQNQIDDLLQQLKD-QKDLQDSKM 1467 Query: 1333 A--FXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQ--LKKSSXXXXXXX 1388 L+ + Y+Q+QEQ N+ Q L +++ Sbjct: 1468 IQNLANQILELENQNQLLSKQLQQSKEQYQQLQEQLQANLTPNGLQEKLLQNTQIIHQQQ 1527 Query: 1389 XXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEY---E 1445 N + + E+T QL++ D +K E ++ ++Q++ + + Sbjct: 1528 EQILALQNQIQTDIPEVTQQLQVADQN-QKKALEEARNWKEKYLNLLEIKQEIPKIQIDD 1586 Query: 1446 KRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLN--- 1502 I+ + E+ + +K ++ AN E K E+ KLI + +I S N Sbjct: 1587 NIIKQMNLEESQDYIQTLVKNYQKANEQEQQAKILINEQKKLINQYENQIEAQHSQNSDI 1646 Query: 1503 -KQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQ---NMVRASSSKIQKHV 1558 K+ A LNK E + ++ + + + Q E++ L ++ Q N + + K + V Sbjct: 1647 IKENAILNKLTETQNSQIERLSKSNQAQSQEMIDLKNQQRQEQYWKNEYQKLALKYGEDV 1706 Query: 1559 SFASDTKQGRDEQLDNTMNKELLD 1582 S S ++ Q+D + E ++ Sbjct: 1707 SNKSPNQEDLINQIDENIQVESIN 1730 Score = 122 bits (295), Expect = 6e-26 Identities = 245/1248 (19%), Positives = 545/1248 (43%), Gaps = 113/1248 (9%) Query: 402 INKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGK-DTLIAQLQLEHQQHM 460 + +N+I +L+ +QS NK+L + E E++ + + L AQL L +Q+ Sbjct: 708 LQQNQI-RLQSELQSKNKELKELEQFQGEQNQPYIQGQINLNDQINNLEAQLILAKKQYQ 766 Query: 461 EGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEID 520 E ++ + E Q+ L + ++I +++ K + +++ E Q+ N +I Sbjct: 767 ELLETSQQNSSPNGLKEKILQQQALIHDYENQINNLSNK-IEQEIPILEGQLATANQQIQ 825 Query: 521 AANKNMIKVKSNHKLKLKQMQKTIDNFSKV-SDSNKEIVRLTEELH-HLSQKVAELE--- 575 A +++ + + L Q + +++ SD K++ +EL+ L Q +LE Sbjct: 826 VAENDILNQEKRYNELLNNKQYLQNPDTQIPSDDLKKLTEKNQELNLQLQQNNRKLEVQL 885 Query: 576 --EEKGNLQLHLVD--YDSGRMIES-------DVYKKMIEMENLAETRLKAISLLESQKF 624 EEK ++ D Y+ + I+ D +K+ +M + + ++ I+ L S K Sbjct: 886 DIEEKLKEEISEKDREYNLAQQIQQIQQDQIKDQQQKINKMIDKEQQLMQEIANLSS-KI 944 Query: 625 DLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLE-EQIDALSASKKELALVIE 683 + +++++ K D +K DI Q+Q D +IK + E ++ + K V++ Sbjct: 945 NQQRDINVDNTKQDNQNNK-DDIIQIQEDDSALKIKQLQEELNKVINENVLKNNECQVLQ 1003 Query: 684 NLKLDKE-------QLYGTIKDLENDKEDIMNKLQNYIQEN-MDLTDKLEKMSAEKISEL 735 LK + E QLY I L+N ++ + + Q+N LT + + IS+L Sbjct: 1004 KLKPENEELRAQQTQLYYQIVQLQNQIHNLESFKPSKQQDNDQQLTFETDPEKTLAISQL 1063 Query: 736 LAKINH--EEQSKIQTQFGIDA-KIQERDLYIENIESELSKYKSRICRLEESIAVMEDRR 792 +I + +IQ Q D K +E + + + + ++S+ LE+ + ++++ Sbjct: 1064 QQQIQQLRNQLQEIQNQRAEDLQKFKEINENGADQQHIIELFQSKQ-NLEQQLRNLQNQL 1122 Query: 793 YSLERKADQLGSYLQEKQKAYSEY--TIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKE 850 + ++ + L +K K +SE+ E++ +L L + +++LL+ + + +E Sbjct: 1123 DNALQEQILIQGQLIQKNKQFSEFCSNYNEEDFKKQLENLNQIIQEQQEKLLQSKQQYQE 1182 Query: 851 L-QKKNQILLEENQNLQI-----SLSDMQQHYNALVEKA-NRTDLAESESTKYQTQLRDL 903 L + +Q L Q ++ + + QQ + ++ N + +Y+ + D Sbjct: 1183 LLELTSQNLTPNGQKEKLLQQANQIHEQQQEIQLMHQQLDNEVPKLQGALAEYKQKYNDS 1242 Query: 904 ESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQ 963 ++ + + +Q L+ Q+ K+ + + F+T+ + ++D T L AQ Sbjct: 1243 QTEIHLLMERYQNLLNQRSKQDQSNDKSFSTK-NNNLQD---------------TNLSAQ 1286 Query: 964 LQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDE 1023 + KN+ N++ +++N+ N+ L ++ + Q E++ +E+ L+ + KD+ Sbjct: 1287 KYDDKNDQTNISDFQDDINRKNI-LQEQEIALMHKQQ----EKFSSELEDLHKQISLKDQ 1341 Query: 1024 EIIALNQKINNAQVSYMSMVSDYESKLAQ----FTTKLENMEEEMQRVSKQLLDSKQHNE 1079 EI+ L K+ + +Y Q T++++ E+ V Q K N+ Sbjct: 1342 EILILKNKLAEGNTEFWK--EEYTKLATQNKGSIKTQIQDSPEQYLIVDLQQQSQKLINQ 1399 Query: 1080 ELQILVREQDD--QIKELKETKLTFEMNIPK--TEGMIISSTIEPMSDDANNVDXXXXXX 1135 +I Q+D + +++ E T + ++ + +E + + M + +++ Sbjct: 1400 IAEIEAERQEDLRKFQKILENDGTKDNSVVQLFSENQQLQQSKRQMQNQIDDLLQQLKDQ 1459 Query: 1136 XXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQL-ETLNTELTGHDVVNQE 1194 +Q I E L+ Q+ L+ +LQ+ + QL E L LT + + QE Sbjct: 1460 KDLQDSKMIQNLANQILE---LENQNQLLSKQLQQSKEQYQQLQEQLQANLTPNGL--QE 1514 Query: 1195 QINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTE 1254 ++ Q + Q + + +L+ ++++ I Q ++A+ Q A EA K + Sbjct: 1515 KLLQNTQIIHQ---QQEQILALQNQIQTDIPEVTQQ--LQVADQ-NQKKALEEARNWKEK 1568 Query: 1255 HELRVQLSAFESKYEQLLDSV--QSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEK 1312 + +++ K Q+ D++ Q + +E + I T+ + N+ + + + L N Q+K Sbjct: 1569 YLNLLEIKQEIPKI-QIDDNIIKQMNLEESQDYIQTLVKNYQKANEQEQQAKILINEQKK 1627 Query: 1313 YADVI-NQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNIN 1371 + NQIE S+ D + L NQ+ Q Q ++++ Sbjct: 1628 LINQYENQIEAQHSQNSDI-IKENAILNKLTETQNSQIERLSKSNQA----QSQEMIDLK 1682 Query: 1372 EENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLE--LKDSEIYQKTHEYTITLTQ 1429 + Q + V++ +L +Q++ ++ I + ++ + Q Sbjct: 1683 NQQRQEQYWKNEYQKLALKYGEDVSNKSPNQEDLINQIDENIQVESINELKNQNDLLQQQ 1742 Query: 1430 RNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIE 1489 D+ E ++ ++++ E L + +L ++ + E++Q +++ ++ + Sbjct: 1743 LIDQIEELKLTKIKFQ---EQLLQAQRQINDLLNNQIPQPTQSQESIQFQNDPQKALQLS 1799 Query: 1490 ELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALEN--QEIEIVTLNDEITNLQNMV 1547 +L ++ SLNKQ+ EL + ++++ K +M +EN E +I++L E LQ+ + Sbjct: 1800 QLK---QQNQSLNKQIEELEQIRKKDLQKFQDM---IENGINENQILSLQKEKQELQSEL 1853 Query: 1548 RASSSKI----QKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDL 1591 R S +K+ Q+ + S Q + +QL + ++ LD +L L Sbjct: 1854 RVSKNKVDNLQQEQLILQSQLTQ-KTKQLIDIHDQIQLDEAKNVQLQL 1900 Score = 120 bits (289), Expect = 3e-25 Identities = 298/1601 (18%), Positives = 668/1601 (41%), Gaps = 164/1601 (10%) Query: 68 SKRIKEHRKATAELLGRPFVPG---ISESLANTLKQKEILMEKIKQYKELSKRSS-TTIV 123 +K +KE + E +P++ G +++ + N + ++++ K KQY+EL + S + Sbjct: 723 NKELKELEQFQGEQ-NQPYIQGQINLNDQINNL--EAQLILAK-KQYQELLETSQQNSSP 778 Query: 124 RXXXXXXXXXXXXXXXQLGDVTHLSNTIKEK----DNALSVLQVKMKIMETTILDLQEKI 179 + +LSN I+++ + L+ ++++ E IL+ +++ Sbjct: 779 NGLKEKILQQQALIHDYENQINNLSNKIEQEIPILEGQLATANQQIQVAENDILNQEKRY 838 Query: 180 NEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRL 239 NE N E ++ ++Q+N +E + D +++L Sbjct: 839 NE------LLNNKQYLQNPDTQIPSDDLKKLTEKNQELNLQLQQNNRKLEVQL-DIEEKL 891 Query: 240 LKDIESKDVRISSLEEANKL----LEAARFEISL---EHSKLAQELEQXXXXXXXXXXXX 292 ++I KD + ++ ++ ++ + +I+ + +L QE+ Sbjct: 892 KEEISEKDREYNLAQQIQQIQQDQIKDQQQKINKMIDKEQQLMQEIANLSSKINQQRDIN 951 Query: 293 XXLAKQSIEPSCEEKTEIEEKGS-LEIANMTELTKKI---ELLEHLNCQIRQTNKELENK 348 KQ + + ++ +I+E S L+I + E K+ +L++ CQ+ Q K + Sbjct: 952 VDNTKQDNQNNKDDIIQIQEDDSALKIKQLQEELNKVINENVLKNNECQVLQKLKPENEE 1011 Query: 349 LATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIA 408 L T+ ++ ++ + K Q + + L +TD + I+ Sbjct: 1012 LRAQQTQLYY---------QIVQLQNQIHNLESFKPSKQQDNDQQLTFETDPE-KTLAIS 1061 Query: 409 KLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHV 468 +L+ IQ L L +E + G D QQH+ L Sbjct: 1062 QLQQQIQQLRNQL--QEIQNQRAEDLQKFKEINENGAD----------QQHII--ELFQS 1107 Query: 469 GTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDE-IDAANKNMI 527 N E ++ +Q QL L ++I + LI+K K E + N+E +N+ Sbjct: 1108 KQNLEQ--QLRNLQNQLDNALQEQI--LIQGQLIQKNKQFSEFCSNYNEEDFKKQLENLN 1163 Query: 528 KVKSNHKLKLKQMQKTIDNFSKVSDSN-------KEIVRLTEELHHLSQKVA----ELEE 576 ++ + KL Q ++ +++ N +++++ ++H Q++ +L+ Sbjct: 1164 QIIQEQQEKLLQSKQQYQELLELTSQNLTPNGQKEKLLQQANQIHEQQQEIQLMHQQLDN 1223 Query: 577 EKGNLQLHLVDYDSG-RMIESDVYKKMIEMENLAETRLKAISLLE---SQKFDLVQELHI 632 E LQ L +Y +++++ M +NL R K + S K + +Q+ ++ Sbjct: 1224 EVPKLQGALAEYKQKYNDSQTEIHLLMERYQNLLNQRSKQDQSNDKSFSTKNNNLQDTNL 1283 Query: 633 LQQKYDEVEDKLADISQLQSD----QVCSEIKSVHLEEQIDALSASKKELALVIENLKLD 688 QKYD+ D+ +IS Q D + E + + +Q + S+ ++L I +LK D Sbjct: 1284 SAQKYDDKNDQ-TNISDFQDDINRKNILQEQEIALMHKQQEKFSSELEDLHKQI-SLK-D 1340 Query: 689 KEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQ 748 +E L K E + E + +N + S E+ L+ + + Q I Sbjct: 1341 QEILILKNKLAEGNTEFWKEEYTKLATQNKGSIKTQIQDSPEQY--LIVDLQQQSQKLIN 1398 Query: 749 TQFGIDAKIQERDL--YIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYL 806 I+A+ QE DL + + +E++ +K S + E+ + + +R ++ + D L L Sbjct: 1399 QIAEIEAERQE-DLRKFQKILENDGTKDNSVVQLFSENQQLQQSKR-QMQNQIDDLLQQL 1456 Query: 807 QEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEEN---- 862 ++++ IQ L N++ L + ++++ KQL + + + ++LQ++ Q L N Sbjct: 1457 KDQKDLQDSKMIQN--LANQILELENQNQLLSKQLQQSKEQYQQLQEQLQANLTPNGLQE 1514 Query: 863 ---QNLQISLSDMQQHYNALVEKANRTDLAE-SESTKYQTQLRDLESNLKRITHEHQTLI 918 QN QI + Q+ AL + +TD+ E ++ + Q + R E + Sbjct: 1515 KLLQNTQI-IHQQQEQILALQNQI-QTDIPEVTQQLQVADQNQKKALEEARNWKEKYLNL 1572 Query: 919 VQKKKEIEDLEIEFNTQIESAIRDKK----VLNEKYEKNIEYVTQLEAQLQEYKNNIENL 974 ++ K+EI ++I+ N + + + + L + Y+K E Q + + E K I Sbjct: 1573 LEIKQEIPKIQIDDNIIKQMNLEESQDYIQTLVKNYQKANEQEQQAKILINEQKKLINQY 1632 Query: 975 NMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINN 1034 +E + N ++I K+ TE ++I +L+ + + +E+I L + Sbjct: 1633 ENQIEAQHSQNSDII-----KENAILNKLTETQNSQIERLSKSNQAQSQEMIDLKNQQRQ 1687 Query: 1035 AQV---SYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQ 1091 Q Y + Y ++ + E++ ++ + Q+ + + +L ++ DQ Sbjct: 1688 EQYWKNEYQKLALKYGEDVSNKSPNQEDLINQIDE-NIQVESINELKNQNDLLQQQLIDQ 1746 Query: 1092 IKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFI 1151 I+ELK TK+ F+ + + + I +D NN ++ Q + + Sbjct: 1747 IEELKLTKIKFQEQLLQAQRQI--------NDLLNN---QIPQPTQSQESIQFQNDPQKA 1795 Query: 1152 QERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTE-- 1209 + S L++Q+ LN +++E +I + + + + +N+ QI L+ + ++L +E Sbjct: 1796 LQLSQLKQQNQSLNKQIEEL-EQIRKKDLQKFQDMIENGINENQILSLQKEKQELQSELR 1854 Query: 1210 -NDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQ---KTEHEL-RVQLSAF 1264 + N + + + + + S + Q+ ++ ++ Q + Q + E++L + QL Sbjct: 1855 VSKNKVDNLQQEQLILQSQLTQKTKQLIDIHDQIQLDEAKNVQLQLQNENDLLKKQLHKI 1914 Query: 1265 ESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEI-- 1322 + +Y++LL +QS LQ K+ + +++ +L+E+ + +Q+E Sbjct: 1915 KEQYQELLQ-LQSENLTPNG----------LQEKILQQTQYIHDLEEQVQSLQHQVETQI 1963 Query: 1323 --LRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKS 1380 L EI + K+ ++ + + + ++ L I E++ ++++ Sbjct: 1964 PQLSGEIVELKLKLKDAITDAQLWNNKYNEVIQIQQERSENQLQKLQLQIAEKDEKIEQQ 2023 Query: 1381 SXXXXXXXXXXXXRV--NDAEAKVLELTHQ---LELKDSEIYQKTHEYTITLTQRNDEFE 1435 ++ + A+AK+L+ Q LE K ++Y L N + Sbjct: 2024 KLKFDQLFQEQISQLSPSSAKAKLLKAFQQIIDLEEKLQAAEDLKNQYQSQLINVN-QSN 2082 Query: 1436 NVRQQLVEYEKRI---EDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEEL- 1491 + +L EY++++ E + ++S+++ + ++ + Q ++E K + Sbjct: 2083 QILDELQEYKQKLEMQEKVNQIQDSQISFYKEQLSQQNQTPSNQQIMDQLENEKQKSQFW 2142 Query: 1492 NVKITESVSLNKQVAELNKALEEEVAKTNEM--QTALENQEI---EIVTLNDEITNLQNM 1546 + TE + + +LN+ ++++ + + Q +N + EI L + LQ + Sbjct: 2143 KQQYTEMIKQKEPQGDLNEIIKQKEGEIVQQFKQPQDQNSQAFLKEIEDLKKQNIYLQQL 2202 Query: 1547 VRASSSKI---QKHVSFASDTKQGRDEQLDNTMNKELLDAV 1584 + + SK+ ++ F + Q +++Q N+ L V Sbjct: 2203 IINTQSKLKTQEQKEQFQEEYSQDQEKQSLGLQNQALAKQV 2243 Score = 117 bits (281), Expect = 3e-24 Identities = 232/1202 (19%), Positives = 523/1202 (43%), Gaps = 104/1202 (8%) Query: 380 SKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVI-QSLNKDLVDKEYVISEKDTXXXXX 438 SK SQ + NQ ++ KNE KL + + ++ ++E +I++ D Sbjct: 1668 SKSNQAQSQEMIDLKNQQRQEQYWKNEYQKLALKYGEDVSNKSPNQEDLINQIDENIQVE 1727 Query: 439 XXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEI-KDVN 497 + Q QL Q +E L T + ++ + Q Q+ LN++I + Sbjct: 1728 SINELKNQNDLLQQQLIDQ--IEELKL----TKIKFQEQLLQAQRQINDLLNNQIPQPTQ 1781 Query: 498 VKDLIEKLKSAEE--QITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNF---SKVSD 552 ++ I+ ++ Q++QL + + NK + +++ K L++ Q I+N +++ Sbjct: 1782 SQESIQFQNDPQKALQLSQLKQQNQSLNKQIEELEQIRKKDLQKFQDMIENGINENQILS 1841 Query: 553 SNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETR 612 KE L EL KV L++E+ LQ L + ++I D++ + I+++ + Sbjct: 1842 LQKEKQELQSELRVSKNKVDNLQQEQLILQSQLTQ-KTKQLI--DIHDQ-IQLDEAKNVQ 1897 Query: 613 LKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALS 672 L+ L+++ L ++LH ++++Y E + QLQS+ + + +Q + Sbjct: 1898 LQ----LQNENDLLKKQLHKIKEQYQE-------LLQLQSENLTPNGLQEKILQQTQYIH 1946 Query: 673 ASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKI 732 ++++ + ++ QL G I +L+ +D + Q + + ++ ++ S ++ Sbjct: 1947 DLEEQVQSLQHQVETQIPQLSGEIVELKLKLKDAITDAQLWNNKYNEVIQIQQERSENQL 2006 Query: 733 SELLAKINHEEQSKIQTQFGIDAKIQER--DLYIENIESELSKYKSRICRLEESIAVMED 790 +L +I +++ Q + D QE+ L + +++L K +I LEE + ED Sbjct: 2007 QKLQLQIAEKDEKIEQQKLKFDQLFQEQISQLSPSSAKAKLLKAFQQIIDLEEKLQAAED 2066 Query: 791 RRYSLERK---ADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHE 847 + + + +Q L E Q+ + +QE VN++ D + ++ + Sbjct: 2067 LKNQYQSQLINVNQSNQILDELQEYKQKLEMQEK--VNQI-----QDSQISFYKEQLSQQ 2119 Query: 848 NKELQKKNQILLEENQNLQISLSDMQQHYNALV-EKANRTDLAE----SESTKYQTQLRD 902 N+ NQ ++++ +N + +Q Y ++ +K + DL E E Q + Sbjct: 2120 NQT--PSNQQIMDQLENEKQKSQFWKQQYTEMIKQKEPQGDLNEIIKQKEGEIVQQFKQP 2177 Query: 903 LESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEA 962 + N + E + L KK+ I ++ NTQ + +++K E++++ EY E Sbjct: 2178 QDQNSQAFLKEIEDL---KKQNIYLQQLIINTQSKLKTQEQK---EQFQE--EYSQDQEK 2229 Query: 963 QLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKD 1022 Q +N + L VEEL ++N +++ Q + S D Q I+E+ + N LL + Sbjct: 2230 QSLGLQN--QALAKQVEELKRINQDILQ---QMNKALSGDDKSQLISELLQKNTLLNLAN 2284 Query: 1023 EEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQ 1082 +++ ++ + N ++ S++ ++N++ KQ + Q+ EL Sbjct: 2285 SKLL-IDLEANQKELFRQGQQQQQSSEM------IKNLDRSDMTDDKQRIADLQNQIEL- 2336 Query: 1083 ILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXL 1142 +Q D K+ +T L + + + + I+ +S + + + Sbjct: 2337 --AGQQIDFWKQKYQTVLN-DFSQQHSPTSLQKQLIDQVSQ-IHQQEEALFVLQQTTDKV 2392 Query: 1143 KVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSK 1202 K+Q E + + LQ + + ++ + ++I + + +L+ + Q+Q+N+ + Sbjct: 2393 KLQNENQI----NSLQREIEIIKDQIDQLQKQLISEQNICQQLS-QQKIQQQQVNEKQIN 2447 Query: 1203 LEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELW-KQHLAQREADFQKTEH-ELRVQ 1260 + EN+ L +V E + + + Q E L +Q LAQ + + + + Q Sbjct: 2448 FWKDKYENN--LKSVHENPEKVQTILKQAEKEAQNLIVEQDLAQINMNLELIDRLRMENQ 2505 Query: 1261 LSAFESKY--EQLLDSVQSSTQEETNKIVTME----QVTSLQNKLQDKEEHLRNLQEKYA 1314 S E K+ +++L+ Q + + ++ T++ Q+T ++ LQ ++ Q+KY Sbjct: 2506 KSQDEIKFYKKRVLELEQQQQKIQPSQYDTIQSRQYQITQMERDLQKAIQNQEFWQQKYN 2565 Query: 1315 DVINQ---IEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNIN 1371 DV+ Q EI + ++ E + + QS ++ Sbjct: 2566 DVVQQNIDKEIGQQGDVQNSASYWRQKYDQAEQNRQELIQKIAEKEKQLEQNMQSFQSML 2625 Query: 1372 EENAQLKKSSXXXXXXXXXXXXRVNDAE-AKVLELTHQLELKD--SEIYQKTHEYTITLT 1428 ++ + + + +N++ + L+ H+ E + E ++ + I+ Sbjct: 2626 KDELKEELTKIRSQEKQKIPEQTLNESNLLQKLKEQHENEKQQLIQEFLRRIDQLLISNV 2685 Query: 1429 QRNDEFENVRQQLVEYEKRIEDLTYEKESELAIL---RLKMHENANHYETMQKESEIERV 1485 Q+ E EN ++ +++YEK+ ++ YE + +L IL +++ + + E E+ I + Sbjct: 2686 QKYPEGENWKELILKYEKQRQNELYELKQQLQILQRSQIQTQDIEFYAERRVYENTINEL 2745 Query: 1486 K--LIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNL 1543 K + + ++ +++ ++V + LE++++ + + L NQ I+ LN+EI L Sbjct: 2746 KSRIQYDDQQELFDTIEYQRKVIQ---GLEDQISFISNQKQHL-NQHIQ--ELNEEIEML 2799 Query: 1544 QN 1545 ++ Sbjct: 2800 RD 2801 Score = 116 bits (279), Expect = 5e-24 Identities = 242/1128 (21%), Positives = 479/1128 (42%), Gaps = 129/1128 (11%) Query: 317 EIANMTELTKKIEL-LEHLNCQIRQTNKE---LENKLATMGTE--SKAVSSPSKKGSPLI 370 EIA M + +K LE L+ QI ++E L+NKLA TE + + + + I Sbjct: 1314 EIALMHKQQEKFSSELEDLHKQISLKDQEILILKNKLAEGNTEFWKEEYTKLATQNKGSI 1373 Query: 371 SRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNE-IAKLEMVIQSLNKDLVDKEYVIS 429 + + + Q S + +NQ + + + E + K + ++++ + S Sbjct: 1374 KTQIQDSPEQYLIVDLQQQSQKLINQIAEIEAERQEDLRKFQKILENDGTKDNSVVQLFS 1433 Query: 430 EKDTXXXXXXXXXXGKDTLIAQL--QLEHQQHMEGPSLIHVGTNTEDVNEIAKVQ-EQLK 486 E D L+ QL Q + Q +L + E+ N++ Q +Q K Sbjct: 1434 ENQQLQQSKRQMQNQIDDLLQQLKDQKDLQDSKMIQNLANQILELENQNQLLSKQLQQSK 1493 Query: 487 ---QELNDEIK-DVNVKDLIEKL-------KSAEEQI----TQLNDEIDAANKNMIKVKS 531 Q+L ++++ ++ L EKL +EQI Q+ +I + + Sbjct: 1494 EQYQQLQEQLQANLTPNGLQEKLLQNTQIIHQQQEQILALQNQIQTDIPEVTQQLQVADQ 1553 Query: 532 NHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSG 591 N K L++ + + + + + +EI ++ + + + Q LEE + +Q + +Y Sbjct: 1554 NQKKALEEARNWKEKYLNLLEIKQEIPKIQIDDNIIKQM--NLEESQDYIQTLVKNYQKA 1611 Query: 592 RMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQE---LHILQQKYDEVEDKLADIS 648 E + E + L I SQ D+++E L+ L + + ++L+ + Sbjct: 1612 NEQEQQAKILINEQKKLINQYENQIEAQHSQNSDIIKENAILNKLTETQNSQIERLSKSN 1671 Query: 649 QLQSDQVCSEIKSVHLEEQIDALSASKKELALV--IENLKLDKEQLYGTIKDLENDKEDI 706 Q QS ++ ++K+ +EQ K L + N ++E L I EN + + Sbjct: 1672 QAQSQEMI-DLKNQQRQEQYWKNEYQKLALKYGEDVSNKSPNQEDLINQID--ENIQVES 1728 Query: 707 MNKLQNYIQE-NMDLTDKLEKMSAEKIS--ELLAKINHEEQSKIQTQFGIDAKIQERDLY 763 +N+L+N L D++E++ KI E L + + + Q + QE + Sbjct: 1729 INELKNQNDLLQQQLIDQIEELKLTKIKFQEQLLQAQRQINDLLNNQIPQPTQSQESIQF 1788 Query: 764 IENIES--ELSKYKSRICRLEESIAVMED-RRYSLERKAD---------QLGSYLQEKQK 811 + + +LS+ K + L + I +E R+ L++ D Q+ S +EKQ+ Sbjct: 1789 QNDPQKALQLSQLKQQNQSLNKQIEELEQIRKKDLQKFQDMIENGINENQILSLQKEKQE 1848 Query: 812 AYSEYTIQE---DELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLE---ENQNL 865 SE + + D L +L KQL++I H+ +L + + L+ EN L Sbjct: 1849 LQSELRVSKNKVDNLQQEQLILQSQLTQKTKQLIDI-HDQIQLDEAKNVQLQLQNENDLL 1907 Query: 866 QISLSDMQQHYNALVE--KANRTDLAESESTKYQTQ-LRDLESNLKRITHEHQTLIVQKK 922 + L +++ Y L++ N T E QTQ + DLE ++ + H+ +T I Q Sbjct: 1908 KKQLHKIKEQYQELLQLQSENLTPNGLQEKILQQTQYIHDLEEQVQSLQHQVETQIPQLS 1967 Query: 923 KEIEDLEIEFNTQIESAIRDKKVLNEKY--------EKNIEYVTQLEAQLQEYKNNIENL 974 EI +L+++ ++ AI D ++ N KY E++ + +L+ Q+ E IE Sbjct: 1968 GEIVELKLK----LKDAITDAQLWNNKYNEVIQIQQERSENQLQKLQLQIAEKDEKIEQQ 2023 Query: 975 NMNVEELNKMNL-----------------ELID--KHVQKQQTQSPDYTEQYINEINKLN 1015 + ++L + + ++ID + +Q + Y Q IN +N+ N Sbjct: 2024 KLKFDQLFQEQISQLSPSSAKAKLLKAFQQIIDLEEKLQAAEDLKNQYQSQLIN-VNQSN 2082 Query: 1016 ALLKQKDE--EIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLD 1073 +L + E + + + +K+N Q S +S + S+ Q + + M++ K Sbjct: 2083 QILDELQEYKQKLEMQEKVNQIQDSQISFYKEQLSQQNQTPSNQQIMDQLENEKQKSQFW 2142 Query: 1074 SKQHNEELQILVREQD-DQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXX 1132 +Q+ E ++ + D ++I + KE ++ + P+ + + ++ + D Sbjct: 2143 KQQYTEMIKQKEPQGDLNEIIKQKEGEIVQQFKQPQDQNS--QAFLKEIEDLKKQNIYLQ 2200 Query: 1133 XXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTG--HDV 1190 LK QE++E QE ++ L + Q ++ +L+ +N ++ + Sbjct: 2201 QLIINTQSKLKTQEQKEQFQEEYSQDQEKQSLGLQNQALAKQVEELKRINQDILQQMNKA 2260 Query: 1191 VNQEQINQLKSKLEQLNT----ENDNLL----STVAEL---------RSSISSAVDQRGF 1233 ++ + +QL S+L Q NT N LL + EL S + +D+ Sbjct: 2261 LSGDDKSQLISELLQKNTLLNLANSKLLIDLEANQKELFRQGQQQQQSSEMIKNLDRSDM 2320 Query: 1234 -----EIAELWKQ-HLAQREADFQKTEHELRV----QLSAFESKYEQLLDSVQSSTQEET 1283 IA+L Q LA ++ DF K +++ + Q + S +QL+D V Q+E Sbjct: 2321 TDDKQRIADLQNQIELAGQQIDFWKQKYQTVLNDFSQQHSPTSLQKQLIDQVSQIHQQE- 2379 Query: 1284 NKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEK 1331 + ++Q T + KLQ+ E + +LQ + + +QI+ L+ ++ E+ Sbjct: 2380 EALFVLQQTTD-KVKLQN-ENQINSLQREIEIIKDQIDQLQKQLISEQ 2425 Score = 89.8 bits (213), Expect = 5e-16 Identities = 207/1121 (18%), Positives = 474/1121 (42%), Gaps = 102/1121 (9%) Query: 230 AEWKDEKQRLLKDIES-KDVRISSLEEANKLLEAARFEIS-LEHSKLAQELEQXXXXXXX 287 ++ K + Q L K IE + +R L++ ++E E L K QEL+ Sbjct: 1799 SQLKQQNQSLNKQIEELEQIRKKDLQKFQDMIENGINENQILSLQKEKQELQSELR---- 1854 Query: 288 XXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELEN 347 ++K ++ +E+ ++ + + + + ++ +I+L E N Q++ N EN Sbjct: 1855 -------VSKNKVDNLQQEQLILQSQLTQKTKQLIDIHDQIQLDEAKNVQLQLQN---EN 1904 Query: 348 KLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEI 407 L K + ++ L+ +S T + ++ Q + D ++++ + Sbjct: 1905 DLL-----KKQLHKIKEQYQELLQLQSENLTPNGLQEKILQQTQYI--HDLEEQVQSLQ- 1956 Query: 408 AKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIH 467 ++E I L+ ++V+ + + + T K + Q+Q E ++ + Sbjct: 1957 HQVETQIPQLSGEIVELKLKLKDAITDAQLWN----NKYNEVIQIQQERSENQLQKLQLQ 2012 Query: 468 VGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAAN--KN 525 + E + + +QL QE ++ + K KL A +QI L +++ AA KN Sbjct: 2013 IAEKDEKIEQQKLKFDQLFQEQISQLSPSSAK---AKLLKAFQQIIDLEEKLQAAEDLKN 2069 Query: 526 MIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTE-ELHHLSQKVAELEEEKGNLQLH 584 + + + + Q+ + + + + +++ ++ + ++ +++++ + N Q+ Sbjct: 2070 QYQSQLINVNQSNQILDELQEYKQKLEMQEKVNQIQDSQISFYKEQLSQQNQTPSNQQI- 2128 Query: 585 LVDYDSGRMIESDVYKKMI-EMENLAETRLKAISLLESQKFDLVQELHILQQKYD----- 638 +D +S +K+ EM E + +++ ++ ++VQ+ Q + Sbjct: 2129 -MDQLENEKQKSQFWKQQYTEMIKQKEPQGDLNEIIKQKEGEIVQQFKQPQDQNSQAFLK 2187 Query: 639 EVEDKLADISQLQS--DQVCSEIKSVHLEEQI-DALSASKKELALVIENLKLDKEQLYGT 695 E+ED LQ S++K+ +EQ + S +++ +L ++N L K+ Sbjct: 2188 EIEDLKKQNIYLQQLIINTQSKLKTQEQKEQFQEEYSQDQEKQSLGLQNQALAKQ--VEE 2245 Query: 696 IKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDA 755 +K + D MNK + ++ +++ L+K + ++ I+ E K + G Sbjct: 2246 LKRINQDILQQMNKALSGDDKSQLISELLQKNTLLNLANSKLLIDLEANQKELFRQG--Q 2303 Query: 756 KIQERDLYIENIE-SELSKYKSRICRLEESIAVMEDRRYSLERKADQ-LGSYLQEKQKAY 813 + Q+ I+N++ S+++ K RI L+ I + + ++K L + Q+ Sbjct: 2304 QQQQSSEMIKNLDRSDMTDDKQRIADLQNQIELAGQQIDFWKQKYQTVLNDFSQQHSPTS 2363 Query: 814 SEYTI--QEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSD 871 + + Q ++ + L + +K L+ E++ LQ++ +I+ ++ LQ L Sbjct: 2364 LQKQLIDQVSQIHQQEEALFVLQQTTDKVKLQNENQINSLQREIEIIKDQIDQLQKQLIS 2423 Query: 872 MQQHYNALVE-KANRTDLAESE----STKYQTQLRDLESNLKRITHEHQTLIVQKKKEIE 926 Q L + K + + E + KY+ L+ + N +++ QT++ Q +KE + Sbjct: 2424 EQNICQQLSQQKIQQQQVNEKQINFWKDKYENNLKSVHENPEKV----QTILKQAEKEAQ 2479 Query: 927 DLEIEFN-TQIESAIR--DK-KVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELN 982 +L +E + QI + D+ ++ N+K + I++ + +L++ + I+ + + Sbjct: 2480 NLIVEQDLAQINMNLELIDRLRMENQKSQDEIKFYKKRVLELEQQQQKIQPSQYDTIQSR 2539 Query: 983 KMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSM 1042 + + +++ +QK Q+ ++ +Q N++ + N D+EI N+A SY Sbjct: 2540 QYQITQMERDLQKA-IQNQEFWQQKYNDVVQQNI-----DKEIGQQGDVQNSA--SYWRQ 2591 Query: 1043 VSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTF 1102 D +N +E +Q+++++ +Q+ + Q +++ D+ +EL + + Sbjct: 2592 KYDQAE---------QNRQELIQKIAEKEKQLEQNMQSFQSMLK--DELKEELTKIRSQE 2640 Query: 1103 EMNIPK---TEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQE 1159 + IP+ E ++ E ++ + VQ+ E + ++ + Sbjct: 2641 KQKIPEQTLNESNLLQKLKEQHENEKQQLIQEFLRRIDQLLISNVQKYPEGENWKELILK 2700 Query: 1160 QSAKLNTELQECYTKI-----IQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLL 1214 + EL E ++ Q++T + E V + IN+LKS+++ + L Sbjct: 2701 YEKQRQNELYELKQQLQILQRSQIQTQDIEFYAERRVYENTINELKSRIQY--DDQQELF 2758 Query: 1215 STVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDS 1274 T+ R I DQ F + KQHL Q + + LR L KY+ D+ Sbjct: 2759 DTIEYQRKVIQGLEDQISFISNQ--KQHLNQHIQELNEEIEMLRDNL----QKYQLQSDN 2812 Query: 1275 VQSSTQEETNKIVTMEQVTSLQNKLQDKE-EHLRNLQEKYA 1314 + E I M++ + + Q + +R Q KY+ Sbjct: 2813 RKKQRLEVLEAISEMKRERTRERDSQKSPFQSMRPSQNKYS 2853 Score = 87.4 bits (207), Expect = 3e-15 Identities = 191/989 (19%), Positives = 414/989 (41%), Gaps = 86/989 (8%) Query: 160 VLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTK--QQ 217 V+Q++ + E + LQ +I EKD+ IE + + K QQ Sbjct: 1994 VIQIQQERSENQLQKLQLQIAEKDEKIEQQKLKFDQLFQEQISQLSPSSAKAKLLKAFQQ 2053 Query: 218 MTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQE 277 + ++E A E + K++ Q L ++ + + L+E + LE ++ S+++ Sbjct: 2054 IIDLEEKLQAAE-DLKNQYQSQLINVNQSNQILDELQEYKQKLEMQEKVNQIQDSQISFY 2112 Query: 278 LEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQ 337 EQ + Q I E + ++K TE+ K+ E LN Sbjct: 2113 KEQLSQQNQTP-------SNQQIMDQLENE---KQKSQFWKQQYTEMIKQKEPQGDLNEI 2162 Query: 338 IRQTNKELENKL---ATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKS-PWSQLSSET 393 I+Q E+ + +++ K + ++ NT SK+K+ + E Sbjct: 2163 IKQKEGEIVQQFKQPQDQNSQAFLKEIEDLKKQNIYLQQLIINTQSKLKTQEQKEQFQEE 2222 Query: 394 LNQDTDKK---INKNEIAKLEMVIQSLNKDLVDK-EYVISEKDTXXXXXXXXXXGKDTLI 449 +QD +K+ + +AK ++ +N+D++ + +S D K+TL Sbjct: 2223 YSQDQEKQSLGLQNQALAKQVEELKRINQDILQQMNKALSGDDKSQLISELLQ--KNTL- 2279 Query: 450 AQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAE 509 L L + + LI + N +++ Q Q +Q+ ++ IK+++ D+ + + Sbjct: 2280 --LNLANSK-----LLIDLEANQKELFR----QGQQQQQSSEMIKNLDRSDMTDD----K 2324 Query: 510 EQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQ 569 ++I L ++I+ A + + K ++ L + + K+++ ++H + Sbjct: 2325 QRIADLQNQIELAGQQIDFWKQKYQTVLNDFSQQ----HSPTSLQKQLIDQVSQIHQQEE 2380 Query: 570 KVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMI-EMENLAETRLKAISLLESQKFDLVQ 628 + L++ ++L + + E ++ K I +++ + L QK Q Sbjct: 2381 ALFVLQQTTDKVKLQNENQINSLQREIEIIKDQIDQLQKQLISEQNICQQLSQQKIQ-QQ 2439 Query: 629 ELHILQQKY--DEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELAL---VIE 683 +++ Q + D+ E+ L + + ++V + +K E Q + ++ + +I+ Sbjct: 2440 QVNEKQINFWKDKYENNLKSVHE-NPEKVQTILKQAEKEAQNLIVEQDLAQINMNLELID 2498 Query: 684 NLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEE 743 L+++ ++ IK + ++ + Q D + + +L I ++E Sbjct: 2499 RLRMENQKSQDEIKFYKKRVLELEQQQQKIQPSQYDTIQSRQYQITQMERDLQKAIQNQE 2558 Query: 744 --QSKIQ--TQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKA 799 Q K Q ID +I ++ + KY +E I + ++ LE+ Sbjct: 2559 FWQQKYNDVVQQNIDKEIGQQGDVQNSASYWRQKYDQAEQNRQELIQKIAEKEKQLEQNM 2618 Query: 800 DQLGSYLQEKQKAYSEYT-IQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQIL 858 S L+++ K E T I+ E ++ +++K L+ +HEN++ Q + L Sbjct: 2619 QSFQSMLKDELK--EELTKIRSQEKQKIPEQTLNESNLLQK--LKEQHENEKQQLIQEFL 2674 Query: 859 LEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEH-QTL 917 +Q L +S++Q++ E N +L + Q +L +L+ L+ + QT Sbjct: 2675 RRIDQLL---ISNVQKY----PEGENWKELILKYEKQRQNELYELKQQLQILQRSQIQTQ 2727 Query: 918 IVQKKKEIEDLEIEFNTQIESAIR--DKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLN 975 ++ E E N +++S I+ D++ L + E + + LE Q+ N ++LN Sbjct: 2728 DIEFYAERRVYENTIN-ELKSRIQYDDQQELFDTIEYQRKVIQGLEDQISFISNQKQHLN 2786 Query: 976 MNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALN---QKI 1032 +++ELN+ +E++ ++QK Q QS + +Q + + ++ + +++ E + Q + Sbjct: 2787 QHIQELNE-EIEMLRDNLQKYQLQSDNRKKQRLEVLEAISEMKRERTRERDSQKSPFQSM 2845 Query: 1033 NNAQVSYMS--MVSDY--ESKLAQFTTKLENMEEEMQRV---SKQLLDSKQHNEELQILV 1085 +Q Y DY S + Q + + +QR+ S Q + S+Q N E+ + Sbjct: 2846 RPSQNKYSQDRYPRDYLRPSNIPQQFSSFKEHNSPIQRIPYPSVQFISSQQENREIPQKL 2905 Query: 1086 REQDDQIKELKETKLTFEMNIPKTEGMII 1114 +E ++E+K T NI K E ++ Sbjct: 2906 QE----LEEVKNKYQTALNNILKLETQVV 2930 Score = 55.6 bits (128), Expect = 1e-05 Identities = 92/484 (19%), Positives = 216/484 (44%), Gaps = 56/484 (11%) Query: 447 TLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIA----KVQEQLK------QELNDEIKDV 496 T++ Q + E Q + L + N E ++ + K Q+++K EL + + + Sbjct: 2469 TILKQAEKEAQNLIVEQDLAQINMNLELIDRLRMENQKSQDEIKFYKKRVLELEQQQQKI 2528 Query: 497 NVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQ-MQKTIDNFSKVSDS-- 553 + ++S + QITQ+ ++ A +N + + ++Q + K I V +S Sbjct: 2529 QPSQY-DTIQSRQYQITQMERDLQKAIQNQEFWQQKYNDVVQQNIDKEIGQQGDVQNSAS 2587 Query: 554 --NKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAET 611 ++ + + L QK+AE E++ L+ ++ + S M++ ++ +++ ++ + + Sbjct: 2588 YWRQKYDQAEQNRQELIQKIAEKEKQ---LEQNMQSFQS--MLKDELKEELTKIRSQEKQ 2642 Query: 612 RLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQI--- 668 ++ +L ES ++E H +K +++ L I QL V + + +E I Sbjct: 2643 KIPEQTLNESNLLQKLKEQHE-NEKQQLIQEFLRRIDQLLISNVQKYPEGENWKELILKY 2701 Query: 669 -----DALSASKKELALVIEN-LKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTD 722 + L K++L ++ + ++ + Y + EN ++ +++Q Q+ + T Sbjct: 2702 EKQRQNELYELKQQLQILQRSQIQTQDIEFYAERRVYENTINELKSRIQYDDQQELFDTI 2761 Query: 723 KLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYK-----SR 777 + ++ + + + ++ I++++Q ++ IQE + IE + L KY+ + Sbjct: 2762 EYQRKVIQGLEDQISFISNQKQH-------LNQHIQELNEEIEMLRDNLQKYQLQSDNRK 2814 Query: 778 ICRLEESIAVMEDRRYSLERKADQLGSY--LQEKQKAYSEYTIQEDEL-----VNRLAVL 830 RLE A+ E +R + Q + ++ Q YS+ D L + + Sbjct: 2815 KQRLEVLEAISEMKRERTRERDSQKSPFQSMRPSQNKYSQDRYPRDYLRPSNIPQQFSSF 2874 Query: 831 MDHDRVVEK------QLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKAN 884 +H+ +++ Q + + EN+E+ +K Q L E Q +L+++ + +VEK Sbjct: 2875 KEHNSPIQRIPYPSVQFISSQQENREIPQKLQELEEVKNKYQTALNNILKLETQVVEKLQ 2934 Query: 885 RTDL 888 + D+ Sbjct: 2935 QDDI 2938 Score = 48.4 bits (110), Expect = 0.002 Identities = 51/177 (28%), Positives = 89/177 (50%), Gaps = 25/177 (14%) Query: 815 EYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQ 874 E + E+ +VL+D +EK+ + ++++N++LQ++ QILL E QN + ++D+QQ Sbjct: 46 EKVLMSFEIQRLNSVLLD----IEKKRIAMKNQNQKLQEREQILLLEIQNQKQQINDIQQ 101 Query: 875 HYNALVEKANRTDLAESEST--KYQTQLRD--LESNLKRITHEHQTLIVQKKKEIEDLEI 930 EK +R L + + T K + Q+RD + +K++ E L+ QK + + Sbjct: 102 K-----EKNSRDQLNQLQRTFSKQENQIRDQLMSDEIKKL-QEENILLEQKLSYL----L 151 Query: 931 EFNTQIESAIRDKKVLNEKYEKNIE-YVTQLEAQLQEYKNNIENLNMNVEELNKMNL 986 E N Q I++ VL +K ++ L LQ ENL N+ + K NL Sbjct: 152 EVNQQ---QIKNDNVLFQKSGGQLKGKENVLPYSLQ---TGFENLQNNIMQFRKGNL 202 >UniRef50_A0BCM0 Cluster: Chromosome undetermined scaffold_10, whole genome shotgun sequence; n=3; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_10, whole genome shotgun sequence - Paramecium tetraurelia Length = 1328 Score = 131 bits (316), Expect = 2e-28 Identities = 209/1113 (18%), Positives = 459/1113 (41%), Gaps = 68/1113 (6%) Query: 466 IHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKN 525 I + T ++ + + L+QEL + + +N++D +K+K ++ I QL +E++ Sbjct: 156 IQLRTENASIDSLQGTIKTLQQELASKQERINLRD--DKIKQQDDIIDQLQNELNHLQGL 213 Query: 526 MIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHL 585 ++V++ LK +Q+ + + + +R L +V LE EK L+ Sbjct: 214 KLEVEN---LK-QQVHFKVQELTTCKEKLAAALREVGALRLYKGEVQVLESEKQLLRDE- 268 Query: 586 VDYDSGRMIESDVYKKMIEMENLA------ETRLKAISLLESQKFDLVQELHILQQKYDE 639 VD+ + ++ K+++E+E L+ E +LK I LE + L ++L E Sbjct: 269 VDH-----LRGEIQKRLLEVEELSFIKASQEAQLKQIPFLEDEISTL---RNLLADAISE 320 Query: 640 VEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDL 699 QLQ++ + + K E ++D + L + ++L +++ Sbjct: 321 KGILQTQFGQLQNENLALDNKYHTQEGELDEFKLDNQRLLQINDHLNEQLQKVRNERNQF 380 Query: 700 ENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQE 759 E D + + L + Q D +K ++ E I EL ++N Q +Q + + AK ++ Sbjct: 381 ERDADQLDKTLHDVQQLLADAEEKNAQLEKE-IKELKDELNKLRQQNLQQELDLQAKDRQ 439 Query: 760 RDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQ 819 + E L++ + I R E+ I +D+ E+ L + E K Q Sbjct: 440 HEQQRVQYEGYLNELQLEIQRKEQLIKNWKDKYLQSEQLVSDL-QFTAELLKQEQIRARQ 498 Query: 820 EDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNAL 879 + + RL H + + + + E +L+K+ Q L EN + + ++Q L Sbjct: 499 LELEIERLKQRQLHQPPPQIEHIVDQDEINQLRKQIQELHRENFDQYQQIQKLKQQIEQL 558 Query: 880 VEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDL-EIEFNTQ-IE 937 N ++ E+E Y ++ L++ L E++ Q + ++ DL + FN + +E Sbjct: 559 ---NNHINILENEKHLYIQEIDRLKTQLNMKVEENE----QMRAKMNDLNQTIFNLKHLE 611 Query: 938 SAIRD-KKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMN-LELIDKH--- 992 S + + ++ +N + + + + QL + +EY++ E N++N L+L + Sbjct: 612 SRVPELEQTINLLRQHSQDLIQQLNVKTKEYEDLYGRYFDKSLEANQVNQLQLSNNKLDI 671 Query: 993 VQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMV---SDYESK 1049 V++++ Q+ + + +N++ N L+ +++E K +V Y+ + S + Sbjct: 672 VRQEEVQNRENVKTDLNKVGVDNDRLR-REKEYYESKYKYLLLEVEYLQRLKAESLQQDP 730 Query: 1050 LAQF--------TTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLT 1101 L + + N+E + Q + QL + NE+ + + + Q+++L+ + Sbjct: 731 LLELRGGNQDDVNEDIANLERQQQVLQDQLAKLQSQNEQKDKEIDDLNAQLRQLQAENIQ 790 Query: 1102 FEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQS 1161 N + + ++ + I + ++N + + Q +Q Sbjct: 791 DLYNKLQQQYSLLQTQITNLQQSSSNSSAEKDNYINELESHINDLQNQLQQLDQQRSKQI 850 Query: 1162 AKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELR 1221 L +LQ+ + +L T+LT ++N ++ +EQLN + + A Sbjct: 851 GDLQAQLQKLLDENNKLRQQLTDLTNKFNSQVSEMNSMQKVIEQLNGFQNEFIKYKALYE 910 Query: 1222 SSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQE 1281 D + ++ +L KQ Q A+ L +++ +++ EQL +Q E Sbjct: 911 RECLVTADLKD-QLGQLDKQ-ARQLAAE----RDNLLDRIAKLQAEIEQLGKQIQVKNDE 964 Query: 1282 ETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXX 1341 + T+ + +L+ E + L++ ++ LR ++ D ++A Sbjct: 965 NAAQSKTVSTLEGQVAQLKPLEAENQRLKQLIDQQTKELGDLRQKLADLQLAADDANKQK 1024 Query: 1342 XXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAK 1401 + N ++Q++ + NE NA LK S+ N Sbjct: 1025 TQFQQLY----NSVNGEFEQLKNKFAAKDNEINA-LKASNTKQESIVKQVKVIDNTNPND 1079 Query: 1402 VLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAI 1461 + L Q+ + E E Q + E + V++ E K ++ K+ EL Sbjct: 1080 LKTLQDQIAQRSKE----NEEIKKKFNQMDVELQKVKKDNTEISK-LQQAIQAKDKELDD 1134 Query: 1462 LRLKMH---ENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAK 1518 L+ K+ +++++ E ++KE E + L +LN + + +LN+ + + + Sbjct: 1135 LKKKLDKFSQDSSNLEKLKKELEAKVNSLNSDLNTSKKNFDNQQNDIKKLNQQINDLQNE 1194 Query: 1519 TNEMQTALENQEIEIVTLNDEITNLQNMVRASS 1551 Q + NQ ++ T N++ ++ +R+ + Sbjct: 1195 IKRQQNIISNQTSDLQTWNNKYASVVKDLRSDN 1227 Score = 109 bits (261), Expect = 8e-22 Identities = 207/1068 (19%), Positives = 446/1068 (41%), Gaps = 91/1068 (8%) Query: 556 EIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKA 615 ++ +L +E L+ ++ L EE G LQ + + I + + +++ + +L+ Sbjct: 29 DVQQLNDENARLNDEIKRLMEELGKLQSQVSELREQTTIIEQLRSDLHNVQHQLDLKLQQ 88 Query: 616 ISLLESQKFDLVQELHILQQKYDEV---EDKLADISQLQSDQVCSEIKSVHLEE---QID 669 I L EL LQ E+KL + Q + D++ S +K E ++ Sbjct: 89 IDDLNHDVQTRDAELFKLQGGSSVTIVTENKLLQM-QSEIDRLQSLLKQREAELDGWRLK 147 Query: 670 ALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSA 729 S K + L EN +D L GTIK L+ +++ +K QE ++L D K Sbjct: 148 YSSLEKVNIQLRTENASIDS--LQGTIKTLQ---QELASK-----QERINLRDDKIKQQD 197 Query: 730 EKISELLAKINHEEQSKIQTQF---GIDAKIQERDLYIENIESELSK------YKSRICR 780 + I +L ++NH + K++ + + K+QE E + + L + YK + Sbjct: 198 DIIDQLQNELNHLQGLKLEVENLKQQVHFKVQELTTCKEKLAAALREVGALRLYKGEVQV 257 Query: 781 LEESIAVMEDR----RYSLERKADQLG--SYLQEKQKAY-SEYTIQEDE---LVNRLAVL 830 LE ++ D R ++++ ++ S+++ Q+A + EDE L N LA Sbjct: 258 LESEKQLLRDEVDHLRGEIQKRLLEVEELSFIKASQEAQLKQIPFLEDEISTLRNLLADA 317 Query: 831 MDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQIS---LSDMQQHYNALVEKA-NRT 886 + +++ Q ++++EN L K E ++ L + H N ++K N Sbjct: 318 ISEKGILQTQFGQLQNENLALDNKYHTQEGELDEFKLDNQRLLQINDHLNEQLQKVRNER 377 Query: 887 DLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVL 946 + E ++ + L D++ L ++ Q +KEI++L+ E N + ++ + L Sbjct: 378 NQFERDADQLDKTLHDVQQLLADAEEKN----AQLEKEIKELKDELNKLRQQNLQQELDL 433 Query: 947 NEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSP-DYTE 1005 K Q E Q +Y+ + L + ++ ++ DK++Q +Q S +T Sbjct: 434 QAKDR-------QHEQQRVQYEGYLNELQLEIQRKEQLIKNWKDKYLQSEQLVSDLQFTA 486 Query: 1006 QYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEE-- 1063 + + + ++ A +Q + EI L Q+ + + + D + ++ Q +++ + E Sbjct: 487 ELLKQ-EQIRA--RQLELEIERLKQRQLHQPPPQIEHIVD-QDEINQLRKQIQELHRENF 542 Query: 1064 --MQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPM 1121 Q++ K +Q N + IL E+ I+E+ K M + + E M + + + Sbjct: 543 DQYQQIQKLKQQIEQLNNHINILENEKHLYIQEIDRLKTQLNMKVEENEQM--RAKMNDL 600 Query: 1122 SDDANNVDXXXXXXXXXXXXLKV--QEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLE 1179 + N+ + + Q ++ IQ+ +V ++ L + + Q+ Sbjct: 601 NQTIFNLKHLESRVPELEQTINLLRQHSQDLIQQLNVKTKEYEDLYGRYFDKSLEANQVN 660 Query: 1180 TLNTELTGHDVVNQEQI---NQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQ----RG 1232 L D+V QE++ +K+ L ++ +ND L S + + + Sbjct: 661 QLQLSNNKLDIVRQEEVQNRENVKTDLNKVGVDNDRLRREKEYYESKYKYLLLEVEYLQR 720 Query: 1233 FEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTME-Q 1291 + L + L + Q +E L + + L +QS +++ +I + Q Sbjct: 721 LKAESLQQDPLLELRGGNQDDVNEDIANLERQQQVLQDQLAKLQSQNEQKDKEIDDLNAQ 780 Query: 1292 VTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXD 1351 + LQ ++ ++ LQ++Y+ + QI L+ + Sbjct: 781 LRQLQ--AENIQDLYNKLQQQYSLLQTQITNLQQSSSNSSAEKDNYINELESHINDLQNQ 838 Query: 1352 L-RTENQSYKQM--QEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQ 1408 L + + Q KQ+ + + + +EN +L++ +N + KV+E + Sbjct: 839 LQQLDQQRSKQIGDLQAQLQKLLDENNKLRQQLTDLTNKFNSQVSEMNSMQ-KVIEQLNG 897 Query: 1409 LE---LKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAIL--- 1462 + +K +Y++ T L + + + +QL + D + ++E+ L Sbjct: 898 FQNEFIKYKALYERECLVTADLKDQLGQLDKQARQLAAERDNLLDRIAKLQAEIEQLGKQ 957 Query: 1463 -RLKMHENANHYETMQK-ESEIERVKLIEELNVKITESV-SLNKQVAELNKALEE-EVAK 1518 ++K ENA +T+ E ++ ++K +E N ++ + + K++ +L + L + ++A Sbjct: 958 IQVKNDENAAQSKTVSTLEGQVAQLKPLEAENQRLKQLIDQQTKELGDLRQKLADLQLAA 1017 Query: 1519 TNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQ 1566 + + + Q++ ++N E L+N A ++I + AS+TKQ Sbjct: 1018 DDANKQKTQFQQL-YNSVNGEFEQLKNKFAAKDNEI--NALKASNTKQ 1062 Score = 37.5 bits (83), Expect = 3.0 Identities = 61/325 (18%), Positives = 135/325 (41%), Gaps = 27/325 (8%) Query: 1245 QREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEE 1304 +R D++ + + E+ +QL D + +E ++ ME++ LQ+++ + E Sbjct: 7 ERAIDYETLIQAEQARNEELENDVQQLNDE-NARLNDEIKRL--MEELGKLQSQVSELRE 63 Query: 1305 HLRNLQEKYADVIN---QIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQ 1361 +++ +D+ N Q+++ +I+D + TEN+ + Sbjct: 64 QTTIIEQLRSDLHNVQHQLDLKLQQIDDLNHDVQTRDAELFKLQGGSSVTIVTENKLLQM 123 Query: 1362 MQE----QSILNINE---ENAQLKKSS-XXXXXXXXXXXXRVNDAEAKVLELTHQLELKD 1413 E QS+L E + +LK SS ++ + + L +L K Sbjct: 124 QSEIDRLQSLLKQREAELDGWRLKYSSLEKVNIQLRTENASIDSLQGTIKTLQQELASKQ 183 Query: 1414 SEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHY 1473 I + + + Q++D + ++ +L ++ L E E+ + K+ E Sbjct: 184 ERINLRDDK----IKQQDDIIDQLQNEL----NHLQGLKLEVENLKQQVHFKVQELTTCK 235 Query: 1474 ETMQKE-SEIERVKLIE-ELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEI 1531 E + E+ ++L + E+ V +E L +V L +++ + + E+ +QE Sbjct: 236 EKLAAALREVGALRLYKGEVQVLESEKQLLRDEVDHLRGEIQKRLLEVEELSFIKASQEA 295 Query: 1532 ---EIVTLNDEITNLQNMVRASSSK 1553 +I L DEI+ L+N++ + S+ Sbjct: 296 QLKQIPFLEDEISTLRNLLADAISE 320 >UniRef50_Q22AS4 Cluster: Putative uncharacterized protein; n=1; Tetrahymena thermophila SB210|Rep: Putative uncharacterized protein - Tetrahymena thermophila SB210 Length = 1441 Score = 130 bits (315), Expect = 2e-28 Identities = 220/1153 (19%), Positives = 508/1153 (44%), Gaps = 104/1153 (9%) Query: 472 TEDVNEIAKVQEQLK-QELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVK 530 T+DV I ++Q +L+ QE + + + +K + ++++ E +IT+L +ID + N+ K+ Sbjct: 212 TQDVR-IEELQRELRGQEEKNVLLNEKIKHMQIQIQNRESEITRLQSKIDIGSLNVDKLS 270 Query: 531 SNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLS---QKVAELEEEKGNLQLHLVD 587 +++++ +Q++K ++ KE ++ EL +L +++ ++EE NL + Sbjct: 271 KDYQIE-QQVEKVERLNHQIDFLTKENHQMDTELKNLKSDLKRIQMIKEENRNLSDKV-- 327 Query: 588 YDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFD-LVQELHILQQKYDEVEDKLAD 646 YD + +ES +++IE + +++ + + QK + ++ ++++D L D Sbjct: 328 YDLNQSLESA--RRIIESHDAKRKQIEDLYKNQLQKLEEKLKNNDASKEEFDNQYKDLED 385 Query: 647 -ISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKED 705 I +LQ + + ++ ++ ++A + K+ + +E+++ +KEQ Sbjct: 386 EIKRLQQENEQLKQEASRADQVVNAYQSDKRVFSQAVESVRAEKEQ-------------- 431 Query: 706 IMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIE 765 ++K++ Y++E + +L+ EK I H + S++Q + + Q+R L E Sbjct: 432 ALSKMEKYVKELEEKQVQLQDYEDEK------AILHSKISQLQREIDLTNANQDR-LSSE 484 Query: 766 N--IESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDEL 823 N + E+ + K+ I LE+ + D+ + + +++ KQK + + I+ + Sbjct: 485 NRLLNDEILRLKANIRSLEQDNLDLNDKYKDAKLEGERI-----LKQKDFLQDQIERAK- 538 Query: 824 VNRLAVLMDHD-RVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEK 882 + D D + + ++ LE +EN LQK+N IL ++ NL+ M Q +L+ + Sbjct: 539 TDTYKFKSDVDTQSIARERLEKLYEN--LQKENSILKKDIGNLE----QMNQQSKSLILE 592 Query: 883 ANRTDLAESESTKYQTQLRDLESNLKRITHEHQ---TLIVQKKKEIEDLEI------EFN 933 AE + + TQ+R L+ +K + +++ +I QK KEI +E N Sbjct: 593 ------AEEKQREQFTQIRILQDQVKELERQNKLSNDVIDQKSKEIRQIESARAETEREN 646 Query: 934 TQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNV----EELNKMNLEL- 988 Q+ + R + +K ++ +E +T LE + + + L ++ E + K+ +L Sbjct: 647 LQLTAIKRKYDDIVDKQKRQLEQITDLEDKRLKVIREADQLKFDIMDKEESIKKLQDQLR 706 Query: 989 IDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYES 1048 I++ + + Q Q + IN+ K+K+ E + ++ + + + E+ Sbjct: 707 IERDERVRLAQELQSISQETDSINQTIQKSKEKETEYSYIALELEKTRERERKQIIEIEA 766 Query: 1049 KLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQI---KELKETKLTFEMN 1105 T++ ME+ + + ++Q+ + EE ++E ++ K KE T + Sbjct: 767 ----LQTEVRKMEQLISQGTRQVENLNNQKEEYLKEIKELRKEMLNTKSDKENGFTKSIQ 822 Query: 1106 IPK---TEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSA 1162 + + T+ +++ + +S + V + E+ + I E +Q Sbjct: 823 LQEKINTQELLVQDLKDSLSKEERKVKNLENEIKILTN--ENTEQRQRIYEIETNNKQLK 880 Query: 1163 KLNTELQECYTKIIQ-LETLNTELT---GHDVVNQEQINQLKSKLEQLNTE---NDNLLS 1215 + L+ ++++ L+ N+E G + Q++I L +L ++N E + + Sbjct: 881 TIAEGLERAKEELLERLQNRNSERVEEEGEKIKLQKEIQSLGKQLNEVNQELKQAQDSIV 940 Query: 1216 TVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSV 1275 T+ + R I +D++ E ++ KQ L Q E D +K + R +LS+ + Q + + Sbjct: 941 TIDQERDEIQEQLDKKILENEKI-KQVLEQYENDLEKL-RDKRNELSSKSDQSVQRVIQL 998 Query: 1276 QSSTQEETNKI-VTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAF 1334 +++ +++ KI + +V + + L K++ L++L V + + L E+ K+A Sbjct: 999 EATIKDQNKKIQQLLLEVDNCKYTLTVKDKELQDLANDLNVVTRENQNLTGEL--VKIAG 1056 Query: 1335 XXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSIL----NINEENAQLKKSSXXXXXXXXX 1390 + + +M++ +L + +N +L++ S Sbjct: 1057 ERDDIRHQLNNVMIEEKKQKQGLRAVEMEKSDLLTQYKQVCIDNERLERQSQDLIIENQN 1116 Query: 1391 XXXRVNDAEAKVLELTHQL---ELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKR 1447 + D E ++ L L E K ++ +T N + E Q + + + Sbjct: 1117 LFRKAQDLEKELALLQGHLGHHEGKQGQMINDLKNMERQITFLNQKLEQADQHIRDIIQE 1176 Query: 1448 IEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQV-A 1506 E++ + +S + + + + N + + E E+++L+E LN+ E + ++ Sbjct: 1177 KENIHRQYDSMMRVSQ-GLEGNRDEMQRQLMTLENEKIQLVENLNMLKRECEAKASELDY 1235 Query: 1507 ELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQ 1566 N+ + E E Q A Q +E+ ++ E + + + + D + Sbjct: 1236 HRNRVSQLEEILLRERQ-AQHRQSLEVQSIIQERDQISRQLDEMKQQNLNLQGYLQDNE- 1293 Query: 1567 GRDEQLDNTMNKE 1579 R+ L N+ K+ Sbjct: 1294 -RNNSLYNSAQKD 1305 Score = 110 bits (264), Expect = 4e-22 Identities = 173/937 (18%), Positives = 387/937 (41%), Gaps = 71/937 (7%) Query: 668 IDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKM 727 ++ L +++ + +N+K + I E E + + I+EN DL + K+ Sbjct: 31 VERLLNENLKISEMYQNVKKQNNEALKNIAKAEQSLEPLKKENAKLIKENNDLHYAMIKV 90 Query: 728 SAEKI---SELLAKINHEEQSKIQTQFGIDAK-IQERDLYIENI--ESELSKYKSRIC-- 779 + + N E K +F +D K + R + EN+ +++L + S++ Sbjct: 91 KEDAELANNRWKTTYNSLEGEKNDLKFLVDQKEARIRKVEDENLALKTKLDTFMSKVYIP 150 Query: 780 ----RLEE------SIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAV 829 LE + + SL +K +Q L + ++EY +E + A Sbjct: 151 STQGGLENLPPSYINANISAPTNISLSKKGNQFD--LNKPLNEFNEYQNNREEEMRNWA- 207 Query: 830 LMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLA 889 D R + ++ E++ E + ++KN +L E+ +++QI + + + L K + L Sbjct: 208 --DQIRTQDVRIEELQRELRGQEEKNVLLNEKIKHMQIQIQNRESEITRLQSKIDIGSLN 265 Query: 890 ESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEK 949 + +K Q+ ++R+ H+ L KE ++ E ++S ++ +++ E+ Sbjct: 266 VDKLSK-DYQIEQQVEKVERLNHQIDFL----TKENHQMDTELK-NLKSDLKRIQMIKEE 319 Query: 950 YEKNIEYVTQLEAQLQEYKNNIEN---LNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQ 1006 + V L L+ + IE+ +E+L K L+ +++ ++ ++ Q Sbjct: 320 NRNLSDKVYDLNQSLESARRIIESHDAKRKQIEDLYKNQLQKLEEKLKNNDASKEEFDNQ 379 Query: 1007 Y---INEINKLNALLKQKDEEIIALNQKINNAQVS---YMSMVSDYESKLAQFTTKLENM 1060 Y +EI +L +Q +E +Q +N Q + V ++ Q +K+E Sbjct: 380 YKDLEDEIKRLQQENEQLKQEASRADQVVNAYQSDKRVFSQAVESVRAEKEQALSKMEKY 439 Query: 1061 EEEMQRVSKQLLDSKQHNEEL--QILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTI 1118 +E++ QL D + L +I +++ + + +L+ E + E + + + I Sbjct: 440 VKELEEKQVQLQDYEDEKAILHSKISQLQREIDLTNANQDRLSSENRLLNDEILRLKANI 499 Query: 1119 EPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQ---ERSVLQEQSAKLNTELQECYTKI 1175 + D N+D ++ ++++F+Q ER+ K + + Q + Sbjct: 500 RSLEQD--NLDLNDKYKDAKLEGERILKQKDFLQDQIERAKTDTYKFKSDVDTQSIARER 557 Query: 1176 IQ--LETLNTE--LTGHDVVNQEQIN-QLKSKLEQLNTENDNLLSTVAELRSSISSAVDQ 1230 ++ E L E + D+ N EQ+N Q KS + + + + + L+ + Q Sbjct: 558 LEKLYENLQKENSILKKDIGNLEQMNQQSKSLILEAEEKQREQFTQIRILQDQVKELERQ 617 Query: 1231 RGF--EIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLD----SVQSSTQEETN 1284 ++ + + + Q E+ +TE E +QL+A + KY+ ++D ++ T E Sbjct: 618 NKLSNDVIDQKSKEIRQIESARAETERE-NLQLTAIKRKYDDIVDKQKRQLEQITDLEDK 676 Query: 1285 KIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIE--DEKVAFXXXXXXXX 1342 ++ + + L+ + DKEE ++ LQ++ ++ L E++ ++ Sbjct: 677 RLKVIREADQLKFDIMDKEESIKKLQDQLRIERDERVRLAQELQSISQETDSINQTIQKS 736 Query: 1343 XXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKV 1402 + E + ++ + + I+ I +++K N E + Sbjct: 737 KEKETEYSYIALELEKTRERERKQIIEIEALQTEVRKMEQLISQGTRQVENLNNQKEEYL 796 Query: 1403 LELTHQLELKDSEIYQKTHEYT--ITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELA 1460 E+ + + K + +T I L ++ + E + Q L + + E E+E+ Sbjct: 797 KEIKELRKEMLNTKSDKENGFTKSIQLQEKINTQELLVQDLKDSLSKEERKVKNLENEIK 856 Query: 1461 IL-------RLKMHE---NANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNK 1510 IL R +++E N +T+ + E + +L+E L + +E V + +L K Sbjct: 857 ILTNENTEQRQRIYEIETNNKQLKTIAEGLERAKEELLERLQNRNSERVEEEGEKIKLQK 916 Query: 1511 ALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMV 1547 ++ + NE+ L+ + IVT++ E +Q + Sbjct: 917 EIQSLGKQLNEVNQELKQAQDSIVTIDQERDEIQEQL 953 Score = 92.3 bits (219), Expect = 1e-16 Identities = 149/789 (18%), Positives = 333/789 (42%), Gaps = 79/789 (10%) Query: 839 KQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQT 898 K + + E + L+K+N L++EN +L HY A+++ +LA + Sbjct: 57 KNIAKAEQSLEPLKKENAKLIKENNDL---------HY-AMIKVKEDAELANNRWKTTYN 106 Query: 899 QLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYV- 957 L +++LK + + + I +++ED + T++++ + KV + +E + Sbjct: 107 SLEGEKNDLKFLVDQKEARI----RKVEDENLALKTKLDTFM--SKVYIPSTQGGLENLP 160 Query: 958 -TQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINE---INK 1013 + + A + N + N +LNK L +++ ++ + ++ +Q + I + Sbjct: 161 PSYINANISAPTNISLSKKGNQFDLNK-PLNEFNEYQNNREEEMRNWADQIRTQDVRIEE 219 Query: 1014 LNALLKQKDEEIIALNQKINNAQVSYM---SMVSDYESKLAQFTTKLENMEEEMQRVSKQ 1070 L L+ ++E+ + LN+KI + Q+ S ++ +SK+ + ++ + ++ Q + +Q Sbjct: 220 LQRELRGQEEKNVLLNEKIKHMQIQIQNRESEITRLQSKIDIGSLNVDKLSKDYQ-IEQQ 278 Query: 1071 LLDSKQHNEELQILVREQDDQIKELKETKLTFE-MNIPKTEGMIISSTIEPMSDDANNVD 1129 + ++ N ++ L +E ELK K + + + K E +S + + N Sbjct: 279 VEKVERLNHQIDFLTKENHQMDTELKNLKSDLKRIQMIKEENRNLSDKVYDL-----NQS 333 Query: 1130 XXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHD 1189 K ++ E+ + + E+ K N +E + Q + L E+ Sbjct: 334 LESARRIIESHDAKRKQIEDLYKNQLQKLEEKLKNNDASKEEFDN--QYKDLEDEIKRLQ 391 Query: 1190 VVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREAD 1249 N EQ+ Q S+ +Q+ + ++ S+ + +Q E + + L +++ Sbjct: 392 QEN-EQLKQEASRADQVVNAYQSDKRVFSQAVESVRAEKEQ-ALSKMEKYVKELEEKQVQ 449 Query: 1250 FQKTEHELRVQLSAFESKYEQL-LDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRN 1308 Q E E + S ++ L + N+++ +++ L+ ++ E+ + Sbjct: 450 LQDYEDEKAILHSKISQLQREIDLTNANQDRLSSENRLLN-DEILRLKANIRSLEQDNLD 508 Query: 1309 LQEKYAD-------VINQIEILRSEIEDEKV-AFXXXXXXXXXXXXXXXXDLRTEN-QSY 1359 L +KY D ++ Q + L+ +IE K + + EN Q Sbjct: 509 LNDKYKDAKLEGERILKQKDFLQDQIERAKTDTYKFKSDVDTQSIARERLEKLYENLQKE 568 Query: 1360 KQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQK 1419 + ++ I N+ + N Q K ++ + +V EL Q +L + I QK Sbjct: 569 NSILKKDIGNLEQMNQQSKSLILEAEEKQREQFTQIRILQDQVKELERQNKLSNDVIDQK 628 Query: 1420 THEYTITLTQRNDEFENVRQQLVEYEKRIEDLT------YEKESELAILRLKMHENANH- 1472 + E + E E QL +++ +D+ E+ ++L RLK+ A+ Sbjct: 629 SKEIR-QIESARAETERENLQLTAIKRKYDDIVDKQKRQLEQITDLEDKRLKVIREADQL 687 Query: 1473 -YETMQKESEIERVKLIEELNVKITESVSLNKQVAELNK---ALEEEVAKTNEMQT---- 1524 ++ M KE I+ KL ++L ++ E V L +++ +++ ++ + + K+ E +T Sbjct: 688 KFDIMDKEESIK--KLQDQLRIERDERVRLAQELQSISQETDSINQTIQKSKEKETEYSY 745 Query: 1525 -ALE---------NQEIEIVTLNDEITNLQNMVRASSSKIQ----KHVSFASDTKQGRDE 1570 ALE Q IEI L E+ ++ ++ + +++ + + + K+ R E Sbjct: 746 IALELEKTRERERKQIIEIEALQTEVRKMEQLISQGTRQVENLNNQKEEYLKEIKELRKE 805 Query: 1571 QLDNTMNKE 1579 L+ +KE Sbjct: 806 MLNTKSDKE 814 Score = 79.0 bits (186), Expect = 1e-12 Identities = 175/968 (18%), Positives = 423/968 (43%), Gaps = 95/968 (9%) Query: 153 EKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXE 212 EK+ ALS ++ +K +E + LQ+ +EK I+ +K Sbjct: 428 EKEQALSKMEKYVKELEEKQVQLQDYEDEK-AILHSKISQLQREIDLTNANQDRLSSENR 486 Query: 213 DTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARF-EISLEH 271 ++ +++ N ++E + D L D + KD ++ E ++L+ F + +E Sbjct: 487 LLNDEILRLKANIRSLEQDNLD-----LND-KYKDAKL----EGERILKQKDFLQDQIER 536 Query: 272 SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELL 331 +K +A++ +E E ++++ S+ ++ L + + Sbjct: 537 AK-------TDTYKFKSDVDTQSIARERLEKLYE---NLQKENSILKKDIGNLEQMNQQS 586 Query: 332 EHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSS 391 + L + + +E ++ + + K + +K + +I +KS +++S ++ Sbjct: 587 KSLILEAEEKQREQFTQIRILQDQVKELERQNKLSNDVIDQKS--KEIRQIESARAETER 644 Query: 392 ETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEY-VISEKDTXXXXXXXXXXGKDTLIA 450 E L K+ + + K + ++ + DL DK VI E D L Sbjct: 645 ENLQLTAIKRKYDDIVDKQKRQLEQIT-DLEDKRLKVIREADQLKFDIMDKEESIKKLQD 703 Query: 451 QLQLEHQQHME-GPSLIHVGTNTEDVNEIAKVQEQLKQELN------DEIKDVNVKDL-- 501 QL++E + + L + T+ +N+ + ++ + E + ++ ++ K + Sbjct: 704 QLRIERDERVRLAQELQSISQETDSINQTIQKSKEKETEYSYIALELEKTRERERKQIIE 763 Query: 502 IEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSN-KEIVRL 560 IE L++ ++ QL + +N+ K + ++K+++K + N ++ + ++L Sbjct: 764 IEALQTEVRKMEQLISQGTRQVENLNNQKEEYLKEIKELRKEMLNTKSDKENGFTKSIQL 823 Query: 561 TEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLE 620 E+++ V +L++ + + + +E+++ K++ EN E R + + Sbjct: 824 QEKINTQELLVQDLKDSLSKEERKV------KNLENEI--KILTNEN-TEQRQRIYEIET 874 Query: 621 SQKFDLVQELHILQQKYDEVEDKLAD-ISQLQSDQVCSEIKSVHLEEQIDALSASKKELA 679 + K +L + + + +++L + + S++V E + + L+++I +L K+L Sbjct: 875 NNK-----QLKTIAEGLERAKEELLERLQNRNSERVEEEGEKIKLQKEIQSLG---KQLN 926 Query: 680 LVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMS------AEKIS 733 V + LK Q +I ++ ++++I +L I EN + LE+ +K + Sbjct: 927 EVNQELK----QAQDSIVTIDQERDEIQEQLDKKILENEKIKQVLEQYENDLEKLRDKRN 982 Query: 734 ELLAKINHEEQSKIQTQFGI---DAKIQERDLYIENIESELSKYKSRICRLEESIAVMED 790 EL +K + Q IQ + I + KIQ+ L ++N + L+ + L + V+ Sbjct: 983 ELSSKSDQSVQRVIQLEATIKDQNKKIQQLLLEVDNCKYTLTVKDKELQDLANDLNVVTR 1042 Query: 791 RRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRL-AVLMDHDRVVEKQLLEIEHENK 849 +L + ++ + + + I+E + L AV M+ ++ Q ++ +N+ Sbjct: 1043 ENQNLTGELVKIAGERDDIRHQLNNVMIEEKKQKQGLRAVEMEKSDLL-TQYKQVCIDNE 1101 Query: 850 ELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKR 909 L++++Q L+ ENQNL D+++ L + L E + Q + DL++ ++ Sbjct: 1102 RLERQSQDLIIENQNLFRKAQDLEKELALL-----QGHLGHHEGKQGQ-MINDLKNMERQ 1155 Query: 910 ITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKN 969 IT +Q L Q + I D+ I++K+ ++ +Y+ + LE E + Sbjct: 1156 ITFLNQKL-EQADQHIRDI-----------IQEKENIHRQYDSMMRVSQGLEGNRDEMQR 1203 Query: 970 NIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALN 1029 + L +L + NL ++ + + + ++ DY + N +++L +L ++ + + Sbjct: 1204 QLMTLENEKIQLVE-NLNMLKRECEAKASEL-DY---HRNRVSQLEEILLRERQAQHRQS 1258 Query: 1030 QKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEEL-QILVREQ 1088 ++ + + +S ++ Q L+ ++ +R + L +S Q ++++ +L ++ Sbjct: 1259 LEVQSI-IQERDQISRQLDEMKQQNLNLQGYLQDNER-NNSLYNSAQKDQKIVPVLEKKI 1316 Query: 1089 DDQIKELK 1096 DD+ + +K Sbjct: 1317 DDKNQLIK 1324 Score = 66.5 bits (155), Expect = 6e-09 Identities = 162/786 (20%), Positives = 330/786 (41%), Gaps = 84/786 (10%) Query: 215 KQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLE-EANKLLEAARFEISLEHSK 273 + + ++ + ++ E Q + K E K+ S + E K E R +I +E Sbjct: 709 RDERVRLAQELQSISQETDSINQTIQKSKE-KETEYSYIALELEKTRERERKQI-IEIEA 766 Query: 274 LAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEH 333 L E+ + L Q E E K +E + + TK I+L E Sbjct: 767 LQTEVRKMEQLISQGTRQVENLNNQKEEYLKEIKELRKEMLNTKSDKENGFTKSIQLQEK 826 Query: 334 LNCQ------IRQTNKELENKLATMGTESKAVSSPSKKGSPLI-----SRKSGRNTASKM 382 +N Q ++ + + E K+ + E K +++ + + I + K + A + Sbjct: 827 INTQELLVQDLKDSLSKEERKVKNLENEIKILTNENTEQRQRIYEIETNNKQLKTIAEGL 886 Query: 383 KSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXX 442 + +L N+++++ + E KL+ IQSL K L + V E Sbjct: 887 ERAKEELLERLQNRNSERVEEEGEKIKLQKEIQSLGKQLNE---VNQELKQAQDSIVTID 943 Query: 443 XGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLI 502 +D + QL ++ +E + V E N++ K++++ + EL+ + D +V+ +I Sbjct: 944 QERDEIQEQLD---KKILENEKIKQVLEQYE--NDLEKLRDK-RNELSSK-SDQSVQRVI 996 Query: 503 E---KLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVR 559 + +K ++I QL E+D K + VK K++Q ++ + V+ N+ Sbjct: 997 QLEATIKDQNKKIQQLLLEVDNC-KYTLTVKD------KELQDLANDLNVVTRENQ---N 1046 Query: 560 LTEELHHLSQKVAELEEEKGNLQLHLVDYDSG-RMIESDVYKKMIEMENLAETRLKAISL 618 LT EL ++ + ++ + N+ + G R +E + + + + + + Sbjct: 1047 LTGELVKIAGERDDIRHQLNNVMIEEKKQKQGLRAVEMEKSDLLTQYKQVCIDNER---- 1102 Query: 619 LESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKEL 678 LE Q DL+ E L +K ++E +LA LQ E K + I+ L ++++ Sbjct: 1103 LERQSQDLIIENQNLFRKAQDLEKELA---LLQGHLGHHEGKQ---GQMINDLKNMERQI 1156 Query: 679 ALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAK 738 + N KL EQ I+D+ +KE+I + + ++ + L ++M + ++ Sbjct: 1157 TFL--NQKL--EQADQHIRDIIQEKENIHRQYDSMMRVSQGLEGNRDEMQRQLMT----- 1207 Query: 739 INHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERK 798 E KIQ ++ +E E SEL +++R+ +LEE ++ R + R+ Sbjct: 1208 ---LENEKIQLVENLNMLKRE----CEAKASELDYHRNRVSQLEE---ILLRERQAQHRQ 1257 Query: 799 ADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDR------VVEKQLLEIEHENKELQ 852 + ++ S +QE+ + + + + +N L D++R +K + K++ Sbjct: 1258 SLEVQSIIQERDQISRQLDEMKQQNLNLQGYLQDNERNNSLYNSAQKDQKIVPVLEKKID 1317 Query: 853 KKNQILLE-ENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRD-----LESN 906 KNQ++ E++ +Q+ + + N ++ + + DL + +Q+ D E N Sbjct: 1318 DKNQLIKTLESEQIQLRQENSKLKLNMVLYQKEKEDLEKRLYNLKDSQMSDTIKSSYEKN 1377 Query: 907 LKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNI--EYVTQLEAQL 964 ++ ++ Q Q + I+ EF + A LN+ KN+ EY L Sbjct: 1378 PRQQDNDQQN--QQGWERIQAERREFQKSLNEASMRSYALNQNV-KNLKKEYDQVLPPSS 1434 Query: 965 QEYKNN 970 + KNN Sbjct: 1435 TKSKNN 1440 Score = 54.0 bits (124), Expect = 3e-05 Identities = 141/670 (21%), Positives = 269/670 (40%), Gaps = 53/670 (7%) Query: 878 ALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIE 937 A+VE+ +L SE YQ + LK I Q+L KK+ + I+ N + Sbjct: 29 AMVERLLNENLKISEM--YQNVKKQNNEALKNIAKAEQSLEPLKKENAK--LIKENNDLH 84 Query: 938 SAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQ 997 A+ KV + N + T + L+ KN+++ L V++ ++ D+++ + Sbjct: 85 YAMI--KVKEDAELANNRWKTTYNS-LEGEKNDLKFL---VDQKEARIRKVEDENLALKT 138 Query: 998 TQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKL 1057 ++ YI L I A N +S D L +F Sbjct: 139 KLDTFMSKVYIPSTQ--GGLENLPPSYINANISAPTNISLSKKGNQFDLNKPLNEFNEYQ 196 Query: 1058 ENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISST 1117 N EEEM+ + Q+ EELQ +R Q+++ L E ++ I E I + Sbjct: 197 NNREEEMRNWADQIRTQDVRIEELQRELRGQEEKNVLLNEKIKHMQIQIQNRESEI--TR 254 Query: 1118 IEPMSDDAN-NVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKII 1176 ++ D + NVD +V++ E + L +++ +++TEL+ + + Sbjct: 255 LQSKIDIGSLNVDKLSKDYQIEQ---QVEKVERLNHQIDFLTKENHQMDTELKNLKSDLK 311 Query: 1177 QLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIA 1236 +++ + E +++ L LE ++ + R I + ++ Sbjct: 312 RIQMIKEENRN----LSDKVYDLNQSLESAR----RIIESHDAKRKQIEDLYKNQLQKLE 363 Query: 1237 ELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTS-- 1294 E K + A +E +F +L ++ + + EQL S + N + ++V S Sbjct: 364 EKLKNNDASKE-EFDNQYKDLEDEIKRLQQENEQLKQEA-SRADQVVNAYQSDKRVFSQA 421 Query: 1295 LQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRT 1354 +++ +KE+ L + EKY + + ++ + EDEK DL Sbjct: 422 VESVRAEKEQALSKM-EKYVKELEEKQVQLQDYEDEKAIL-----HSKISQLQREIDLTN 475 Query: 1355 ENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDS 1414 NQ ++ ++ L +N+E +LK + + DA+ LE L+ KD Sbjct: 476 ANQD--RLSSENRL-LNDEILRLKANIRSLEQDNLDLNDKYKDAK---LEGERILKQKDF 529 Query: 1415 EIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYE 1474 Q T T ++D V Q + E R+E L + E +IL+ ++ + E Sbjct: 530 LQDQIERAKTDTYKFKSD----VDTQSIARE-RLEKLYENLQKENSILK----KDIGNLE 580 Query: 1475 TMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIV 1534 M ++S+ ++ E+ + T+ L QV EL + + +++ Q + E ++IE Sbjct: 581 QMNQQSKSLILEAEEKQREQFTQIRILQDQVKELER--QNKLSNDVIDQKSKEIRQIESA 638 Query: 1535 TLNDEITNLQ 1544 E NLQ Sbjct: 639 RAETERENLQ 648 >UniRef50_A2F8N8 Cluster: Putative uncharacterized protein; n=2; Eukaryota|Rep: Putative uncharacterized protein - Trichomonas vaginalis G3 Length = 1996 Score = 130 bits (315), Expect = 2e-28 Identities = 244/1298 (18%), Positives = 527/1298 (40%), Gaps = 90/1298 (6%) Query: 212 EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271 E T+++ ++ +E E +++ E+++ K+ +++ +I E N LE + E + Sbjct: 736 EATEEKYSEREELMKPTEPDFQQEEKQ--KEEVNEEKQIDRKE--NDFLEETKEE-QIHE 790 Query: 272 SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELL 331 K++ +++ A++S S E +E EE+ ++ +++ Sbjct: 791 VKVSDDIKDDFKEEQKEIEHESNNAEESTNKSKEVVSETEEESKVQTKERENPSEEETKE 850 Query: 332 EHLNCQIRQTNK-ELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLS 390 E + ++ K E ++ E + K + +K + P+ + Sbjct: 851 EPFEDEYKEETKDENTEEIKEEPFEDETKEENKDKNKEETKEEEPFEDETKEEEPFEDEN 910 Query: 391 SETLNQDT---DKKINKNEIAK---LEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXG 444 E ++T +K NK E + E + NKD +E KD Sbjct: 911 KEETKEETKEENKDENKEETKEEEPFEDETKEENKDENKEETKEETKDKSKEETKEETKD 970 Query: 445 KDTLIAQLQLE-HQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIE 503 + E +++ + + N E+ E K + + ++ DE K+ + E Sbjct: 971 ETKEEEPFDGETKEENKDENKEENKDENKEETKEENKEETKEEEPFEDETKEETKDETKE 1030 Query: 504 KLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEE 563 + K ++ DE K K ++ + K + ++T + ++ +E T+E Sbjct: 1031 ETKDETKEEEPFEDESKEETKEENKDENKEETKEETKEETKEEEPFEDENKEETKEETKE 1090 Query: 564 LHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQK 623 + EE K + + + D Y++ + EN + + E + Sbjct: 1091 DEPFEDETK--EENKEEEPFEDENKEETKEDNKDDYEEETKHENNVQEQ-------EDEP 1141 Query: 624 FDLVQELHILQQKYDEV-EDKLADISQLQSDQVCSEIKSV-HLEEQIDALSASKKELALV 681 + + + ++++EV +D+ + + +++ E+K Q D + Sbjct: 1142 TNKANPIASVDEEFEEVFKDEDREFEKHSQEELNREVKEEREFIPQKDETKDQESNHEDF 1201 Query: 682 IENLKLDKEQLYGTIKDLENDK-EDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKIN 740 E +K +++ TIK+ E K E + N I+E D+ +K E+++ +K+ E+ + N Sbjct: 1202 EEEIKEEQKIDEDTIKEEEEQKTEKVQNDFDEEIKEE-DIKEKHEEVTKDKV-EMNEEQN 1259 Query: 741 HEEQSKIQTQFGIDAKIQERDL-------YIENIESELSKYKSRICRLEESIAVMEDRRY 793 EE+ + + + I+ I E+++ I++ E E+ Y + R E+S V E+R Sbjct: 1260 DEEKQQQEVESTIEEDITEQNVEPKKEEQTIQDFEEEVQNYDDK--REEQSEKVHEEREI 1317 Query: 794 SL-------ERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEH 846 L E K ++L ++K++ + E +E+ + + E+QL E E Sbjct: 1318 VLNIEQPQEEEKKEELHEEEEKKEELHEEEEKKEELHEEEKKEELHEEEKKEEQLHEEEE 1377 Query: 847 ENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESN 906 E KE ++ EE + ++ L + ++ E+ L E E K + QL + E Sbjct: 1378 ETKE-----ELHEEEEEKIE-KLHEEEKKEELHEEEKKEEQLHEEEEEKKEEQLHE-EEE 1430 Query: 907 LKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLN-EKYEKNIEYVTQLEAQLQ 965 K HE +KK+E+ + E + E K+ L+ E+ E+ E + + E + + Sbjct: 1431 KKEELHEE-----EKKEELHEEEKKEELHEEEEEEKKEELHEEEEEEKKEELHEEEEKKE 1485 Query: 966 EYKNNIENLNMNVEELNKMNLELIDKHVQKQQT-QSPDYTEQYINEINKLNALLKQKDEE 1024 E + IE L+ EE K L ++ +K++ + + E+ +I KL+ ++K E+ Sbjct: 1486 EEEEKIEKLHEEEEEEKKEELHEEEEEEKKEELHEEEEKKEEEEEKIEKLHEEEEKKKEQ 1545 Query: 1025 IIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQIL 1084 N +++Y + + E ++ K EE+ + + D K+ EE + + Sbjct: 1546 --------TNEEINYNPAIKEVEGPESEEENKYRKDEEDFEDEKNEESDYKKQKEESESV 1597 Query: 1085 VREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEP--------MSDDANNVDXXXXXXX 1136 +E ++ E + E N PK E ++ T ++DD + Sbjct: 1598 AKELEETSTENRNNNQE-ETNQPKLENSSLNITEVKEETEEKVNITDDFETENQNEDRET 1656 Query: 1137 XXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQI 1196 + +E E I+E+ E+ + E QE + I+ E D +E+ Sbjct: 1657 DAETEKAIHQENEQIREKDFHDEKQIENEEEKQEILKEPIEERNFQQENDFKD-NEEEEK 1715 Query: 1197 NQLKSKLEQLNTENDNL--LSTVAELRSSISSAVDQRGFEI--AELWKQHLAQREADFQK 1252 + + K+E+L+ + + + L E + + +++ ++ E K+ L + E + Sbjct: 1716 KEEEEKIEKLHEKEEKIEKLHEEEEKKEELHEEEEKKEEQLHEEEEKKEELHEEEKKEEL 1775 Query: 1253 TEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEK 1312 E E + +L E K EQL + + +E+ ++ E+ + K KEE L +EK Sbjct: 1776 HEEEKKEELHEEEKKEEQLHE--EEKKEEQLHEEEKKEEQLHEEEK---KEEQLHE-EEK 1829 Query: 1313 YADVINQIEILRSEI-EDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNIN 1371 + +++ E ++ E+EK + + E Q +++ +++ ++ Sbjct: 1830 KEEQLHEEEKKEEQLHEEEKKEELHEEEEKKEEQLHEEEEEKKEEQLHEEEEKKE--ELH 1887 Query: 1372 EENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEI-YQKTHEYTITLTQR 1430 EE + ++ + E + H L D EI ++ E + + Sbjct: 1888 EEEKKEEQPHEEVVVVEEKMEQPQEEEEDNEADGIHSLSDFDEEISTEEKVEIKVQEKEE 1947 Query: 1431 NDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHE 1468 N++F+ ++++E EK +++ E+ +E R K E Sbjct: 1948 NNDFDAEEEKILE-EKLEKEIIEEENNETEDDRPKKSE 1984 Score = 101 bits (241), Expect = 2e-19 Identities = 262/1426 (18%), Positives = 575/1426 (40%), Gaps = 101/1426 (7%) Query: 173 LDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMT-KMQENFIAMEAE 231 +D +K +EK+Q +++ + E +++ K QE + + Sbjct: 627 IDSAQKESEKEQAKQSEETSNLESEFESEKHKESSKEETESDNDKLSDKKQEKDKETDDD 686 Query: 232 WKDE--KQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXX 289 +++E K ++ + E K I S E +K + E ++++ + E+ Sbjct: 687 FEEEGKKDQITQSEEEKLNEIIS-SEGDKEKDFHFIEEKKPNNEIQDDFEEATEEKYSER 745 Query: 290 XXXXXLAKQSIEPSCEEKTEIEEKGSLEIA--NMTELTKKIELLE-HLNCQIRQTNKELE 346 + + ++K E+ E+ ++ + E TK+ ++ E ++ I+ KE + Sbjct: 746 EELMKPTEPDFQQEEKQKEEVNEEKQIDRKENDFLEETKEEQIHEVKVSDDIKDDFKEEQ 805 Query: 347 NKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNE 406 ++ ++ ++ SK+ +S T + ++P + + E +D K+ K+E Sbjct: 806 KEIEHESNNAEESTNKSKEVVSETEEESKVQTKER-ENPSEEETKEEPFEDEYKEETKDE 864 Query: 407 IAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLI 466 + + ++ + E KD +D + E + E Sbjct: 865 NT------EEIKEEPFEDETKEENKDKNKEETKEEEPFEDETKEEEPFEDENKEETKEET 918 Query: 467 HVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIE--KLKSAEEQITQLNDEIDAANK 524 N ++ E K +E + E +E KD N ++ E K KS EE + DE Sbjct: 919 KE-ENKDENKEETKEEEPFEDETKEENKDENKEETKEETKDKSKEETKEETKDETKEEEP 977 Query: 525 NMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLH 584 + K +K + K+ K +N + + NKE + EE K +E K + Sbjct: 978 FDGETKEENKDENKEENKD-ENKEETKEENKEETK-EEEPFEDETKEETKDETKEETKDE 1035 Query: 585 LVDYDSGRMIESDVYKKMIEMENLAETRLKAIS-LLESQKF-DLVQELHILQQKYDE-VE 641 + + + K+ + EN ET+ + E + F D +E + K DE E Sbjct: 1036 TKEEEPFEDESKEETKEENKDENKEETKEETKEETKEEEPFEDENKEETKEETKEDEPFE 1095 Query: 642 DKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIE--NLKLDKEQLYGTI-KD 698 D+ + ++ + + E K E+ D K V E + +K ++ ++ Sbjct: 1096 DETKEENK-EEEPFEDENKEETKEDNKDDYEEETKHENNVQEQEDEPTNKANPIASVDEE 1154 Query: 699 LENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELL-AKINHE---EQSKIQTQFGID 754 E +D + + + QE ++ K E+ + E + NHE E+ K + + D Sbjct: 1155 FEEVFKDEDREFEKHSQEELNREVKEEREFIPQKDETKDQESNHEDFEEEIKEEQKIDED 1214 Query: 755 AKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYS 814 +E + E ++++ + E+ V +D+ E + D+ EKQ+ Sbjct: 1215 TIKEEEEQKTEKVQNDFDEEIKEEDIKEKHEEVTKDKVEMNEEQNDE------EKQQQEV 1268 Query: 815 EYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQ 874 E TI+ED + + ++ ++ E+++ + + +++++ + EE + + +++ Q Sbjct: 1269 ESTIEED-ITEQNVEPKKEEQTIQDFEEEVQNYDDKREEQSEKVHEERE-IVLNIEQPQ- 1325 Query: 875 HYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNT 934 E+ + +L E E K +L + E K HE + KK+E+ + E + Sbjct: 1326 ------EEEKKEELHEEEEKK--EELHE-EEEKKEELHEEE-----KKEELHEEEKKEEQ 1371 Query: 935 QIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQ 994 E K+ L+E+ E+ IE + + E + + ++ + ++ EE K +L ++ + Sbjct: 1372 LHEEEEETKEELHEEEEEKIEKLHEEEKKEELHEEEKKEEQLHEEEEEKKEEQLHEEEEK 1431 Query: 995 KQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFT 1054 K++ + E+ E K ++++E+ L+++ + + + + + + Sbjct: 1432 KEELHEEEKKEELHEEEKKEELHEEEEEEKKEELHEEEEEEKKEELHEEEEKKEEEEEKI 1491 Query: 1055 TKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMII 1114 KL EEE + K+ L ++ E+ + L E++ + +E ++ + E K E Sbjct: 1492 EKLHEEEEEEK---KEELHEEEEEEKKEELHEEEEKKEEEEEKIEKLHEEEEKKKEQTNE 1548 Query: 1115 SSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTK 1174 P + + ++EE+F E++ +E K E E K Sbjct: 1549 EINYNPAIKEVEGPESEEENKYR-------KDEEDFEDEKN--EESDYKKQKEESESVAK 1599 Query: 1175 IIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFE 1234 +LE +TE + NQE+ NQ K L + N+ E ++ D FE Sbjct: 1600 --ELEETSTENRNN---NQEETNQPK-----LENSSLNITEVKEETEEKVNITDD---FE 1646 Query: 1235 IAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTS 1294 + + +A+ +K H+ Q+ + E+ +++ + ++E K E+ Sbjct: 1647 TEN--QNEDRETDAETEKAIHQENEQIREKDFHDEKQIENEEE--KQEILKEPIEERNFQ 1702 Query: 1295 LQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRT 1354 +N +D EE + +E+ + +++ E ++ +E+ + + Sbjct: 1703 QENDFKDNEEEEKKEEEEKIEKLHEKEEKIEKLHEEE----------EKKEELHEEEEKK 1752 Query: 1355 ENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDS 1414 E Q +++ +++ L+ E+ +L + E K E H+ E K+ Sbjct: 1753 EEQLHEEEEKKEELHEEEKKEELHEEEKKEELHEEEKKEEQLHEEEKKEEQLHEEEKKEE 1812 Query: 1415 EIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDL-TYEKESELAILRLKMHENANHY 1473 +++++ + ++ E E +QL E EK+ E L EK+ EL K E + Sbjct: 1813 QLHEEEKK-----EEQLHEEEKKEEQLHEEEKKEEQLHEEEKKEELHEEEEKKEEQLHEE 1867 Query: 1474 ETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEI 1533 E +KE ++ EE ++ E +Q E +EE++ + E + E I Sbjct: 1868 EEEKKEEQLHEE---EEKKEELHEEEKKEEQPHEEVVVVEEKMEQPQEEEEDNEADGIHS 1924 Query: 1534 VTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKE 1579 ++ DE + + V + +++ F ++ ++ +E+L+ + +E Sbjct: 1925 LSDFDEEISTEEKVEIKVQEKEENNDFDAEEEKILEEKLEKEIIEE 1970 Score = 83.0 bits (196), Expect = 6e-14 Identities = 215/1110 (19%), Positives = 434/1110 (39%), Gaps = 90/1110 (8%) Query: 534 KLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRM 593 +L L++ ++ + S+VS S +E+L H+S E +EE + + + S R Sbjct: 411 RLSLRRSSESSNQSSQVSSSR------SEKLPHISSSRKE-KEEISSSRKEKEEISSSRK 463 Query: 594 IESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSD 653 + ++ E E ++ +R + + S+K +E+ +++ +E+ + ++ S Sbjct: 464 EKEEISSSRKEKEEISSSRKEKEEISSSRKEK--EEISSSRKEKEEISSSRKEKEEISSS 521 Query: 654 QV-CSEIKSVHLE-EQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQ 711 + EI S E E+I + K+ L + N+ K + +++ ++E + K Sbjct: 522 RKEKEEISSSRKEKEEISSSRKEKENTQLGLSNIIKGKLSTFD-VEEKPKEREFEVKKSS 580 Query: 712 NYIQENMDLTDKLEKMSAEKISE-LLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESE 770 +N ++ ++ S + ++ ++ EE SK + F + I E +++ Sbjct: 581 EEENKNNEIPSEIITESYNETNDDFESEKPKEEVSKSENDFESEKHIDSAQKESEKEQAK 640 Query: 771 LSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQK----------AYSEYTIQE 820 S+ S + ES E + E D+L QEK K + T E Sbjct: 641 QSEETSNLESEFESEKHKESSKEETESDNDKLSDKKQEKDKETDDDFEEEGKKDQITQSE 700 Query: 821 DELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISL-----SDMQQH 875 +E +N + + + D+ + +E + N E+Q + EE + + L D QQ Sbjct: 701 EEKLNEI-ISSEGDKEKDFHFIEEKKPNNEIQDDFEEATEEKYSEREELMKPTEPDFQQE 759 Query: 876 --YNALVEKANRTDLAES---ESTKYQTQLRDLE--SNLKRITHEHQTLIVQKKKEIEDL 928 V + + D E+ E TK + Q+ +++ ++K E Q I + E+ Sbjct: 760 EKQKEEVNEEKQIDRKENDFLEETK-EEQIHEVKVSDDIKDDFKEEQKEIEHESNNAEES 818 Query: 929 EIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLE- 987 + + + KV ++ E E T+ E EYK E + N EE+ + E Sbjct: 819 TNKSKEVVSETEEESKVQTKERENPSEEETKEEPFEDEYKE--ETKDENTEEIKEEPFED 876 Query: 988 ---LIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVS 1044 +K K++T+ + E E K++ +E K N + + Sbjct: 877 ETKEENKDKNKEETKEEEPFEDETKEEEPFEDENKEETKEETKEENKDENKEETKEEEPF 936 Query: 1045 DYESKLAQFTTKLENMEEEMQRVSKQLL--DSKQHNEELQILVREQDDQIK-ELKETKLT 1101 + E+K E +EE + SK+ ++K +E + E ++ K E KE Sbjct: 937 EDETKEENKDENKEETKEETKDKSKEETKEETKDETKEEEPFDGETKEENKDENKEENKD 996 Query: 1102 FEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQS 1161 K E + EP D+ + +EEE F E +E++ Sbjct: 997 ENKEETKEENKEETKEEEPFEDETKEETKDETKEETKD---ETKEEEPFEDES---KEET 1050 Query: 1162 AKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLK-SKLEQLNTENDNLLSTVAEL 1220 + N + + TK E E D +E + K + + T+ +N E Sbjct: 1051 KEENKDENKEETKEETKEETKEEEPFEDENKEETKEETKEDEPFEDETKEENKEEEPFED 1110 Query: 1221 RSSISSAVDQR-GFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSST 1279 + + D + +E + ++ ++E + + + FE ++ + + Sbjct: 1111 ENKEETKEDNKDDYEEETKHENNVQEQEDEPTNKANPIASVDEEFEEVFKDEDREFEKHS 1170 Query: 1280 QEETNKIVTME--------QVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSE-IE-- 1328 QEE N+ V E + ++ +D EE ++ Q+ D I + E ++E ++ Sbjct: 1171 QEELNREVKEEREFIPQKDETKDQESNHEDFEEEIKEEQKIDEDTIKEEEEQKTEKVQND 1230 Query: 1329 -DEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQE-QSIL--NINEENAQLKKSSXXX 1384 DE++ +N KQ QE +S + +I E+N + KK Sbjct: 1231 FDEEIKEEDIKEKHEEVTKDKVEMNEEQNDEEKQQQEVESTIEEDITEQNVEPKKEEQT- 1289 Query: 1385 XXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEY 1444 + D E +V + E + ++++ E I L + E +++L E Sbjct: 1290 ----------IQDFEEEVQNYDDKREEQSEKVHE---EREIVLNIEQPQEEEKKEELHEE 1336 Query: 1445 EKRIEDLTYEKESELAI----LRLKMHENANHYETMQKESEIERVKLIEELNVKITESVS 1500 E++ E+L E+E + + + ++HE E + +E E + +L EE KI E + Sbjct: 1337 EEKKEELHEEEEKKEELHEEEKKEELHEEEKKEEQLHEEEEETKEELHEEEEEKI-EKLH 1395 Query: 1501 LNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEI--TNLQNMVRASSSKIQKHV 1558 ++ EL++ ++E E + E Q E +E+ + + K + H Sbjct: 1396 EEEKKEELHEEEKKEEQLHEEEEEKKEEQLHEEEEKKEELHEEEKKEELHEEEKKEELHE 1455 Query: 1559 SFASDTKQGRDEQLDNTMNKELLDAVPRAE 1588 + K+ E+ + +EL + + E Sbjct: 1456 EEEEEKKEELHEEEEEEKKEELHEEEEKKE 1485 >UniRef50_Q6RT24 Cluster: Centromere associated protein-E; n=13; Eutheria|Rep: Centromere associated protein-E - Mus musculus (Mouse) Length = 2474 Score = 130 bits (314), Expect = 3e-28 Identities = 288/1427 (20%), Positives = 606/1427 (42%), Gaps = 149/1427 (10%) Query: 244 ESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPS 303 E++D+++ L+E N+L E E E + Q + + Q +E Sbjct: 523 ENEDLKLK-LKEKNELEEFELLEQKEERDQEMQLMHEVSNLKNLIKHAEEY--NQDLEND 579 Query: 304 CEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESK--AVSS 361 K ++ ++ +I N+ E + E + + T+ E+ M T S V+ Sbjct: 580 LSSKVKLLKEKEEQIKNLQEYIDA-QKSEKMKIDLSYTSDATEDLKQAMRTLSDLDTVAL 638 Query: 362 PSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEI-AKLEMVIQSLNKD 420 +KK S + R+ ++K ++LS ++D ++ + ++ AK +M D Sbjct: 639 DAKKESAFL-----RSENLELKEKINELSDSRKQMESDIQMYQRQLEAKKKM-----QTD 688 Query: 421 LVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAK 480 L DKE ++ ++ G L++ L+LE + + +++N+ A+ Sbjct: 689 L-DKELQLAFQEISKLSALVDGKG---LLSNLELEKR----------ITDLQKELNKEAE 734 Query: 481 VQEQLKQELN--DEIKDV--NVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLK 536 ++ L++E+N E+K + V+ L +L E++ + E + M S + Sbjct: 735 EKQTLQEEVNLLSELKSLPSEVETLRRELYEKSEELHIITTEREKLFSEMAHKDSRIQGL 794 Query: 537 LKQMQKTIDNF--SKVSDSNKEIV-RLTEELH-HLSQKVAELEEEKGNLQLHLVDYDSGR 592 L+++ T D+ S++S + + E LH L + A + EE+ L+ + Sbjct: 795 LEEIGNTRDDLATSQLSRRGSDGEWQALESLHAELEHRHAGVLEERERLKQEI------G 848 Query: 593 MIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQS 652 + + ++++ LE + + + L+ ++ +E+E + + + ++ Sbjct: 849 ALSKEAESLAFSLDSVKAELSHKTQELEQKTVEGQERLNKMEALREELESRDSSLQSVEK 908 Query: 653 DQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLEN----DKEDIMN 708 ++V K +++ AL+ KK L + E+L+ +++QL I+D N +E ++N Sbjct: 909 EKVLLTEKLQQALKEVKALTQEKKNLKQLQESLQTERDQLRSDIQDTVNMNIDTQEQLLN 968 Query: 709 KLQNYIQENMDLTDKLEKMSAEKISE-LLAKINHEEQSKIQTQF-GIDAKIQE-RDLYIE 765 L++ ++++ + + L+ +AE++S+ L K + + Q + GID + + L Sbjct: 969 ALES-LKQHQETINMLKMKAAEELSDNLHVKDRGGARDEAQQKMDGIDEQNESAHTLLGG 1027 Query: 766 NIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKA----YSEYTIQED 821 ++E+++ + +I L + + ++ S+ + +QL L+E + E I D Sbjct: 1028 GKDNEVTEEQRKIDSLMQENSGLQQTLESVRAEKEQLKMDLKENIEMSIENQEELRILRD 1087 Query: 822 ELVNRLAV-LMDHDRVVEK-QLL------------EIEHENKELQKKNQILL---EENQN 864 EL + V + D EK Q L ++E +N++LQ+ Q LL E Sbjct: 1088 ELKRQQEVAAQEKDHATEKTQELSRTQERLAKTEEKLEEKNQKLQETQQQLLSTQEAMSK 1147 Query: 865 LQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTL-IVQKKK 923 LQ + DM+ N + + E+E + +L + +K IT E L +Q+ Sbjct: 1148 LQAKVIDMESLQNEFRNQGLALERVETEKLELAQRLHESYEEVKSITKERNDLKELQESF 1207 Query: 924 EIEDLEI-EFNTQIES-AIRDKKVLNEKYEKNIEY---VTQLEAQLQEYK---NNIENLN 975 EIE ++ E+ +IE+ ++ K+ LN + EY +T+L + E + + ++ Sbjct: 1208 EIEKKQLKEYAREIEAEGLQAKEELNIAHANLKEYQEIITELRGSISENEAQGASTQDTA 1267 Query: 976 MNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNA------LLKQKDEEI--IA 1027 + EL EL+++ + ++ E+ +N + + A + + EI + Sbjct: 1268 KSAPELQGEVPELLEQELLPVVKEARHSAEK-VNGLEPVGAHSRTVHSMTMEGIEIGNLR 1326 Query: 1028 LNQKINNAQVSYMSMVSDYES-KLAQFTTKLE--NMEEEMQRVSKQLLDSKQHNEELQIL 1084 L +K+ +Q+ + + E + Q T ++E ++E+ +R L++++ + Sbjct: 1327 LTKKLEESQMEISCLTREREDLRRTQETLQVECTQLKEDARRTLANHLETEEELNLARCC 1386 Query: 1085 VREQDDQIKELKETKLTFEMNIPKTEGMIISST------IEPMSDDANNVDXXXXXXXXX 1138 ++EQ+++I L + E + G + +T ++ + + + Sbjct: 1387 LKEQENKIDTLITSLSQRETELSSVRGQLALTTAELERKVQELCEKQEELTRKETSEAQG 1446 Query: 1139 XXXLKVQEEEEFIQERSVLQEQSA---KLNTELQECYTKI-------IQLETLNTELTGH 1188 Q E + + S LQ + +LNT+L+E ++ +L + L Sbjct: 1447 KMSELEQLRELLLAQASALQNAESDRLRLNTQLEESQEEMKTLREEREELRRMQEALHVE 1506 Query: 1189 DVVNQEQINQLKSKLEQL-NTENDNL-LSTVAELRSSISSAVD--QRGFEIAELWKQHLA 1244 +E + ++ SKL++L N E + L + T+ E + S +D + E + + + Sbjct: 1507 SEQQKESMKEISSKLQELQNKEYECLAMKTINETQGS-RCEMDHLNQQLEAQKSTLEKVE 1565 Query: 1245 QREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEE 1304 + + HE ++ + + ++L + T E ++E+ + K +KEE Sbjct: 1566 MENVNLTQRLHETLEEMRSVAKERDELWSMEERLTVERDQLKKSLEETVT---KGMEKEE 1622 Query: 1305 HLRNLQ---EKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQ 1361 LR E++ + IN++ + S+ DE DLR + Q Sbjct: 1623 ELRVAHVHLEEHQETINKLRKMVSDYTDEISHTQGDLKHTNAVVEAQNQDLREKEHQLSQ 1682 Query: 1362 MQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQL--ELKDSEIYQK 1419 + + + ++ QLKK + E + LELT QL LK + K Sbjct: 1683 V-KADLRETVDQMEQLKKK-------LEAQSSTLESREIEKLELTQQLNENLKKITLVTK 1734 Query: 1420 THEYTITLTQR-NDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENA--NHYETM 1476 ++ + + +E + +R+ L + E R DL +++ +A + LK H+ ETM Sbjct: 1735 ENDSLKIMDEALREERDQLRKSLQQTEAR--DLENQEKLRIAHMNLKEHQETIDRLMETM 1792 Query: 1477 -QKESEIERVKL-IEELNVKITESV----SLNKQVAELNKALEEEVAKTNEMQTALENQE 1530 +K EI +K+ +E +N+K+ E V + +Q +L E + E L E Sbjct: 1793 SEKTEEISNMKMELENVNMKLQEKVQELKTSERQRVKLKADASEAKKELKEQGLTLSKIE 1852 Query: 1531 IEIVTLNDEI-TNLQNM--VRASSSKIQKHVSFASDTKQGRDEQLDN 1574 +E + L +I NL+ M VR ++K + RD+ DN Sbjct: 1853 MENLNLAQKIHENLEEMKSVRKERDDLKK---LEEILRMERDQLKDN 1896 Score = 127 bits (307), Expect = 2e-27 Identities = 258/1307 (19%), Positives = 539/1307 (41%), Gaps = 111/1307 (8%) Query: 337 QIRQTNKELENKLAT-MGTESKAVSSPSKKGSPLISRKSGRNTASK----MKSPWSQLSS 391 +++ +N E E K+ T + T + S S + + L+ K G + AS + + L+ Sbjct: 427 KMKDSNYEKEFKVPTSITTRKRKTSVTSLRENSLM--KFGESAASSEFEMLNNTLESLAE 484 Query: 392 ETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQ 451 + T +N ++L + N ++D E + E + ++ + + Sbjct: 485 VEWSSATTLLSEENVESELNSLNAQYNDLVLDYEQLRRENEDLKLKLKEKNELEEFELLE 544 Query: 452 LQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQ 511 + E Q M+ L+H +N ++ + K E+ Q+L +++ ++ LK EEQ Sbjct: 545 QKEERDQEMQ---LMHEVSNLKN---LIKHAEEYNQDLENDLSSK-----VKLLKEKEEQ 593 Query: 512 ITQLNDEIDAANKNMIKVK----SNHKLKLKQMQKTIDNFSKVS-DSNKEIVRLTEELHH 566 I L + IDA +K+ S+ LKQ +T+ + V+ D+ KE L E Sbjct: 594 IKNLQEYIDAQKSEKMKIDLSYTSDATEDLKQAMRTLSDLDTVALDAKKESAFLRSENLE 653 Query: 567 LSQKVAELEEEK----GNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQ 622 L +K+ EL + + ++Q++ ++ + +++D+ K++ LA + +S L Sbjct: 654 LKEKINELSDSRKQMESDIQMYQRQLEAKKKMQTDLDKEL----QLAFQEISKLSALVDG 709 Query: 623 KFDLVQELHILQQKYD---EVEDKLADISQLQSD-QVCSEIKSVHLEEQIDALSASKKEL 678 K L+ L + ++ D E+ + + LQ + + SE+KS L +++ L E Sbjct: 710 K-GLLSNLELEKRITDLQKELNKEAEEKQTLQEEVNLLSELKS--LPSEVETLRRELYEK 766 Query: 679 ALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQE--NMDLTDKLEKMSAEKISELL 736 + + + ++E+L+ + ++ + ++ ++ N + L+ + + + L Sbjct: 767 SEELHIITTEREKLFSEMAHKDSRIQGLLEEIGNTRDDLATSQLSRRGSDGEWQALESLH 826 Query: 737 AKINH------EEQSKIQTQFGIDAKIQERDLY-IENIESELSKYKSRICRLEESIAVME 789 A++ H EE+ +++ + G +K E + ++++++ELS +K++ LE+ + Sbjct: 827 AELEHRHAGVLEERERLKQEIGALSKEAESLAFSLDSVKAELS-HKTQ--ELEQKTVEGQ 883 Query: 790 DRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVL--MDHDRVVEKQLLE-IEH 846 +R +E ++L S Q E + ++L L + + ++ KQL E ++ Sbjct: 884 ERLNKMEALREELESRDSSLQSVEKEKVLLTEKLQQALKEVKALTQEKKNLKQLQESLQT 943 Query: 847 ENKELQKKNQILLEEN----QNLQISLSDMQQHY---NALVEKANRTDLAESESTKYQTQ 899 E +L+ Q + N + L +L ++QH N L KA +L+++ K + Sbjct: 944 ERDQLRSDIQDTVNMNIDTQEQLLNALESLKQHQETINMLKMKAAE-ELSDNLHVKDRGG 1002 Query: 900 LRD-LESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVT 958 RD + + I ++++ ++ E +I+S +++ L + E Sbjct: 1003 ARDEAQQKMDGIDEQNESAHTLLGGGKDNEVTEEQRKIDSLMQENSGLQQTLESVRAEKE 1062 Query: 959 QLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALL 1018 QL+ L+E NIE N EEL + EL K Q+ Q D+ + E+++ L Sbjct: 1063 QLKMDLKE---NIEMSIENQEELRILRDEL--KRQQEVAAQEKDHATEKTQELSRTQERL 1117 Query: 1019 KQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEE-------MQRVSKQL 1071 + +E++ NQK+ Q +S + SKL +E+++ E ++RV + Sbjct: 1118 AKTEEKLEEKNQKLQETQQQLLS-TQEAMSKLQAKVIDMESLQNEFRNQGLALERVETEK 1176 Query: 1072 LDSKQ--HN--EELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANN 1127 L+ Q H EE++ + +E++D +KEL+E+ E K I + ++ N Sbjct: 1177 LELAQRLHESYEEVKSITKERND-LKELQES-FEIEKKQLKEYAREIEAEGLQAKEELNI 1234 Query: 1128 VDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNT---- 1183 L+ E Q S + +AK ELQ ++++ E L Sbjct: 1235 AHANLKEYQEIITELRGSISENEAQGAST--QDTAKSAPELQGEVPELLEQELLPVVKEA 1292 Query: 1184 -----ELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRG------ 1232 ++ G + V +E + N L + E + IS +R Sbjct: 1293 RHSAEKVNGLEPVGAHSRTVHSMTMEGIEIGNLRLTKKLEESQMEISCLTREREDLRRTQ 1352 Query: 1233 ----FEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVT 1288 E +L K+ + A+ +TE EL + + + ++ + S +Q ET Sbjct: 1353 ETLQVECTQL-KEDARRTLANHLETEEELNLARCCLKEQENKIDTLITSLSQRETELSSV 1411 Query: 1289 MEQVTSLQNKLQDKEEHLRNLQEKYA-DVINQIEILRSEIEDEKVAFXXXXXXXXXXXXX 1347 Q+ +L+ K + L QE+ ++ + SE+E + Sbjct: 1412 RGQLALTTAELERKVQELCEKQEELTRKETSEAQGKMSELEQLRELLLAQASALQNAESD 1471 Query: 1348 XXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTH 1407 LR Q + +E L EE +L++ + + +K+ EL + Sbjct: 1472 R---LRLNTQLEESQEEMKTLR--EEREELRRMQEALHVESEQQKESMKEISSKLQELQN 1526 Query: 1408 -QLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKM 1466 + E + +T + N + E + L + E +LT L +R Sbjct: 1527 KEYECLAMKTINETQGSRCEMDHLNQQLEAQKSTLEKVEMENVNLTQRLHETLEEMRSVA 1586 Query: 1467 HENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTAL 1526 E + +M++ +ER +L + L +T+ + +++ + LEE N+++ + Sbjct: 1587 KERDELW-SMEERLTVERDQLKKSLEETVTKGMEKEEELRVAHVHLEEHQETINKLRKMV 1645 Query: 1527 ENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLD 1573 + EI ++ + +V A + +++ S K E +D Sbjct: 1646 SDYTDEISHTQGDLKHTNAVVEAQNQDLREKEHQLSQVKADLRETVD 1692 Score = 97.9 bits (233), Expect = 2e-18 Identities = 231/1148 (20%), Positives = 480/1148 (41%), Gaps = 101/1148 (8%) Query: 477 EIAKVQEQLKQELNDEIKDVNV-KDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSN--- 532 EIA +++QL +E+N + + + KD + +L ++ + ++ DE K M+ S+ Sbjct: 351 EIADLRKQL-EEVNTKTRAQEMEKDQLAQLLDEKDLLQKVQDEKINNLKRMLVTSSSIAL 409 Query: 533 -HKLKLKQMQKTIDNFSKVSDSNKEI-VRLTEELHHLSQKVAELEEEKGNLQLHLVDYDS 590 +L++K+ ++ + K+ DSN E ++ + +K + + +L S Sbjct: 410 QQELEIKRKRRVTWCYGKMKDSNYEKEFKVPTSITTRKRKTSVTSLRENSLMKFGESAAS 469 Query: 591 GRM-IESDVYKKMIEMENLAETRLKA-------ISLLESQKFDLVQELHILQQKYDEVED 642 + ++ + + E+E + T L + ++ L +Q DLV + L+++ ++++ Sbjct: 470 SEFEMLNNTLESLAEVEWSSATTLLSEENVESELNSLNAQYNDLVLDYEQLRRENEDLKL 529 Query: 643 KLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLEND 702 KL + ++L+ ++ + + E Q+ ++ K L E D E + L + Sbjct: 530 KLKEKNELEEFELLEQKEERDQEMQLMHEVSNLKNLIKHAEEYNQDLENDLSSKVKLLKE 589 Query: 703 KEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDL 762 KE+ + LQ YI K++ +E L K S + T +DAK + L Sbjct: 590 KEEQIKNLQEYIDAQKSEKMKIDLSYTSDATEDL-KQAMRTLSDLDT-VALDAKKESAFL 647 Query: 763 YIENIESELSKYKSRICRLEESIAVMED--RRY--SLERKADQLGSYLQEKQKAYSEYTI 818 EN+E K +I L +S ME + Y LE K +E Q A+ E + Sbjct: 648 RSENLE-----LKEKINELSDSRKQMESDIQMYQRQLEAKKKMQTDLDKELQLAFQEIS- 701 Query: 819 QEDELVNRLAVLMDHDRVVEKQLLEIEHE-NKELQKKNQILLEEN--QNLQISLSDMQQH 875 + LV+ +L + + +EK++ +++ E NKE ++K + E N L+ S+++ Sbjct: 702 KLSALVDGKGLLSNLE--LEKRITDLQKELNKEAEEKQTLQEEVNLLSELKSLPSEVETL 759 Query: 876 YNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHE-----HQTLIVQKKKEIEDLEI 930 L EK+ + +E K +++ +S ++ + E Q + D E Sbjct: 760 RRELYEKSEELHIITTEREKLFSEMAHKDSRIQGLLEEIGNTRDDLATSQLSRRGSDGEW 819 Query: 931 EFNTQIESAI--RDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLEL 988 + + + + R VL E+ E+ + + L + + +++++ EL+ EL Sbjct: 820 QALESLHAELEHRHAGVLEER-ERLKQEIGALSKEAESLAFSLDSVK---AELSHKTQEL 875 Query: 989 IDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYES 1048 K V+ Q+ + E E+ ++ L+ ++E + L +K+ A + + ++ + Sbjct: 876 EQKTVEGQERLNK--MEALREELESRDSSLQSVEKEKVLLTEKLQQA-LKEVKALTQEKK 932 Query: 1049 KLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPK 1108 L Q E+++ E ++ + D+ N + Q + + +K+ +ET +M + Sbjct: 933 NLKQLQ---ESLQTERDQLRSDIQDTVNMNIDTQEQLLNALESLKQHQETINMLKMKAAE 989 Query: 1109 --TEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQER----SVLQEQSA 1162 ++ + + + +D L ++ E +E+ S++QE S Sbjct: 990 ELSDNLHVKDRGGARDEAQQKMDGIDEQNESAHTLLGGGKDNEVTEEQRKIDSLMQENSG 1049 Query: 1163 KLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRS 1222 L L+ + QL+ E + NQE++ L+ +L++ E Sbjct: 1050 -LQQTLESVRAEKEQLKMDLKENIEMSIENQEELRILRDELKRQQEVAAQEKDHATEKTQ 1108 Query: 1223 SISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEE 1282 +S ++ +A+ ++ L ++ Q+T+ +L A +++D ++S E Sbjct: 1109 ELSRTQER----LAKT-EEKLEEKNQKLQETQQQLLSTQEAMSKLQAKVID-MESLQNEF 1162 Query: 1283 TNKIVTMEQVTS----LQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXX 1338 N+ + +E+V + L +L + E ++++ ++ N ++ L+ E EK Sbjct: 1163 RNQGLALERVETEKLELAQRLHESYEEVKSITKER----NDLKELQESFEIEKKQLKEYA 1218 Query: 1339 XXXXXXXXXXXXDLRTENQSYKQMQE---QSILNINEENAQLKKSSXXXXXXXXXXXXRV 1395 +L + + K+ QE + +I+E AQ + Sbjct: 1219 REIEAEGLQAKEELNIAHANLKEYQEIITELRGSISENEAQGASTQDTAKSAPELQGEVP 1278 Query: 1396 NDAEAKVL----ELTHQLELKDSEIYQKTHEYTI-TLTQRNDEFENVR--QQLVEYEKRI 1448 E ++L E H E + H T+ ++T E N+R ++L E + I Sbjct: 1279 ELLEQELLPVVKEARHSAEKVNGLEPVGAHSRTVHSMTMEGIEIGNLRLTKKLEESQMEI 1338 Query: 1449 EDLTYEKE------SELAILRLKMHEN-----ANHYETMQ---------KESEIERVKLI 1488 LT E+E L + ++ E+ ANH ET + KE E + LI Sbjct: 1339 SCLTREREDLRRTQETLQVECTQLKEDARRTLANHLETEEELNLARCCLKEQENKIDTLI 1398 Query: 1489 EELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEI-EIVTLNDEITNLQNMV 1547 L+ + TE S+ Q+A LE +V + E Q L +E E E+ L+ ++ Sbjct: 1399 TSLSQRETELSSVRGQLALTTAELERKVQELCEKQEELTRKETSEAQGKMSELEQLRELL 1458 Query: 1548 RASSSKIQ 1555 A +S +Q Sbjct: 1459 LAQASALQ 1466 Score = 88.2 bits (209), Expect = 2e-15 Identities = 166/859 (19%), Positives = 337/859 (39%), Gaps = 81/859 (9%) Query: 750 QFGIDAKIQERDLYIENIESE---LSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYL 806 QF AK + Y+ + ++ L +Y+ I L + + + + + E + DQL L Sbjct: 321 QFASTAKYMKNTPYVNEVSNDEALLKRYRREIADLRKQLEEVNTKTRAQEMEKDQLAQLL 380 Query: 807 QEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKE---LQKKNQILLEENQ 863 EK +Q++++ N +L+ + +Q LEI+ + + K E+ Sbjct: 381 DEKDLLQK---VQDEKINNLKRMLVTSSSIALQQELEIKRKRRVTWCYGKMKDSNYEKEF 437 Query: 864 NLQISLSDMQQHYNALVEKANR-TDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKK 922 + S++ ++ + + N ES ++ L + +L + T ++ ++ Sbjct: 438 KVPTSITTRKRKTSVTSLRENSLMKFGESAASSEFEMLNNTLESLAEVEWSSATTLLSEE 497 Query: 923 KEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELN 982 +L N Q + D + L + E +++ + + +L+E+ E L E Sbjct: 498 NVESELN-SLNAQYNDLVLDYEQLRRENE-DLKLKLKEKNELEEF----ELLEQKEERDQ 551 Query: 983 KMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYM-- 1040 +M L +++ + +Y + N+++ LLK+K+E+I L + I+ + M Sbjct: 552 EMQLMHEVSNLKNLIKHAEEYNQDLENDLSSKVKLLKEKEEQIKNLQEYIDAQKSEKMKI 611 Query: 1041 --SMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELK-- 1096 S SD L Q L +++ K+ + N EL+ + E D K+++ Sbjct: 612 DLSYTSDATEDLKQAMRTLSDLDTVALDAKKESAFLRSENLELKEKINELSDSRKQMESD 671 Query: 1097 --------ETKLTFEMNIPKTEGMIIS--STIEPMSDD---ANNVDXXXXXXXXXXXXLK 1143 E K + ++ K + S + + D +N++ K Sbjct: 672 IQMYQRQLEAKKKMQTDLDKELQLAFQEISKLSALVDGKGLLSNLELEKRITDLQKELNK 731 Query: 1144 VQEEEEFIQER----SVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQL 1199 EE++ +QE S L+ +++ T +E Y K +L + TE + +++ Sbjct: 732 EAEEKQTLQEEVNLLSELKSLPSEVETLRRELYEKSEELHIITTEREKLFSEMAHKDSRI 791 Query: 1200 KSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRV 1259 + LE++ D+L ++ R S ++ E L R A + L+ Sbjct: 792 QGLLEEIGNTRDDLATSQLSRRGSDGE------WQALESLHAELEHRHAGVLEERERLKQ 845 Query: 1260 QLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQ 1319 ++ A + E L S+ S E ++K +EQ T + +K E LR E + Sbjct: 846 EIGALSKEAESLAFSLDSVKAELSHKTQELEQKTVEGQERLNKMEALREELESRDSSLQS 905 Query: 1320 IE---ILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTE-NQSYKQMQEQSILNINEENA 1375 +E +L +E + + L+TE +Q +Q+ +NI+ + Sbjct: 906 VEKEKVLLTEKLQQALKEVKALTQEKKNLKQLQESLQTERDQLRSDIQDTVNMNIDTQEQ 965 Query: 1376 QLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKD-----SEIYQK------THEYT 1424 L ++ AE EL+ L +KD E QK +E Sbjct: 966 LLNALESLKQHQETINMLKMKAAE----ELSDNLHVKDRGGARDEAQQKMDGIDEQNESA 1021 Query: 1425 ITL---------TQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYET 1475 TL T+ + +++ Q+ ++ +E + EKE L++ + EN Sbjct: 1022 HTLLGGGKDNEVTEEQRKIDSLMQENSGLQQTLESVRAEKEQ----LKMDLKENIEMSIE 1077 Query: 1476 MQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVT 1535 Q+E I R +L + V E ++ EL++ +E +AKT E LE + ++ Sbjct: 1078 NQEELRILRDELKRQQEVAAQEKDHATEKTQELSRT-QERLAKTEE---KLEEKNQKLQE 1133 Query: 1536 LNDEITNLQNMVRASSSKI 1554 ++ + Q + +K+ Sbjct: 1134 TQQQLLSTQEAMSKLQAKV 1152 Score = 84.6 bits (200), Expect = 2e-14 Identities = 175/885 (19%), Positives = 378/885 (42%), Gaps = 94/885 (10%) Query: 242 DIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLA---KQ 298 ++ + +I SL + N L+ + E +L +L++ L K+ Sbjct: 1032 EVTEEQRKIDSLMQENSGLQQTLESVRAEKEQLKMDLKENIEMSIENQEELRILRDELKR 1091 Query: 299 SIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKA 358 E + +EK EK L K E LE N ++++T ++L L+T Sbjct: 1092 QQEVAAQEKDHATEKTQELSRTQERLAKTEEKLEEKNQKLQETQQQL---LSTQ------ 1142 Query: 359 VSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLN 418 + SK + +I +S +N ++ +E L + E+ + L Sbjct: 1143 -EAMSKLQAKVIDMESLQNEFRNQGLALERVETEKLELAQRLHESYEEVKSITKERNDLK 1201 Query: 419 KDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHV--GTNTEDVN 476 + + + + I +K G +L + H E +I G+ +E+ Sbjct: 1202 E--LQESFEIEKKQLKEYAREIEAEGLQAK-EELNIAHANLKEYQEIITELRGSISENEA 1258 Query: 477 EIAKVQEQLKQ--ELNDEIKDVNVKDLIEKLKSAEEQITQLND-EIDAANKNMIKVKSNH 533 + A Q+ K EL E+ ++ ++L+ +K A ++N E A+ + + Sbjct: 1259 QGASTQDTAKSAPELQGEVPELLEQELLPVVKEARHSAEKVNGLEPVGAHSRTVHSMTME 1318 Query: 534 KLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEE----KGNLQLHLVDYD 589 +++ ++ T K+ +S EI LT E L + L+ E K + + L ++ Sbjct: 1319 GIEIGNLRLT----KKLEESQMEISCLTREREDLRRTQETLQVECTQLKEDARRTLANHL 1374 Query: 590 SGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHI----LQQKYDEVEDKLA 645 + + E EN +T + ++S E++ + +L + L++K E+ +K Sbjct: 1375 ETEEELNLARCCLKEQENKIDTLITSLSQRETELSSVRGQLALTTAELERKVQELCEKQE 1434 Query: 646 DISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKED 705 ++++ ++ + ++ K LE+ + L A A ++N + D+ +L +++ + + + Sbjct: 1435 ELTRKETSE--AQGKMSELEQLRELLLAQ----ASALQNAESDRLRLNTQLEESQEEMKT 1488 Query: 706 IMNKLQNY--IQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLY 763 + + + +QE + + + +K S ++IS L ++ ++E + + I+ + Q Sbjct: 1489 LREEREELRRMQEALHVESEQQKESMKEISSKLQELQNKEYECLAMKT-IN-ETQGSRCE 1546 Query: 764 IENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYS---EYTIQE 820 ++++ +L KS + ++E + R L +++ S +E+ + +S T++ Sbjct: 1547 MDHLNQQLEAQKSTLEKVEMENVNLTQR---LHETLEEMRSVAKERDELWSMEERLTVER 1603 Query: 821 DELVNRLAVLMDHDRVVEKQL----LEIEHENKELQKKNQILLEENQNLQISLSDMQQHY 876 D+L L + E++L + +E + + K +++ + + + D++ H Sbjct: 1604 DQLKKSLEETVTKGMEKEEELRVAHVHLEEHQETINKLRKMVSDYTDEISHTQGDLK-HT 1662 Query: 877 NALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQI 936 NA+VE N+ DL E E QL ++++L+ + + L KKK LE + +T + Sbjct: 1663 NAVVEAQNQ-DLREKEH-----QLSQVKADLRETVDQMEQL---KKK----LEAQSST-L 1708 Query: 937 ESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQ 996 ES +K L ++ +N++ +T + + K E L ++L K Q Sbjct: 1709 ESREIEKLELTQQLNENLKKITLVTKENDSLKIMDEALREERDQLRK----------SLQ 1758 Query: 997 QTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTK 1056 QT++ D Q I +N LK+ E I L M +S+ +++ + Sbjct: 1759 QTEARDLENQEKLRIAHMN--LKEHQETIDRL-----------METMSEKTEEISNMKME 1805 Query: 1057 LENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLT 1101 LEN+ ++Q ++L S++ +L+ + + KELKE LT Sbjct: 1806 LENVNMKLQEKVQELKTSERQRVKLK---ADASEAKKELKEQGLT 1847 Score = 69.7 bits (163), Expect = 6e-10 Identities = 176/930 (18%), Positives = 390/930 (41%), Gaps = 85/930 (9%) Query: 240 LKDIESK-DVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQ 298 LK+ E+K D I+SL + L + R +++L ++L +++++ A+ Sbjct: 1387 LKEQENKIDTLITSLSQRETELSSVRGQLALTTAELERKVQELCEKQEELTRKETSEAQG 1446 Query: 299 SIEPSCEEKTEI--EEKGSLEIANMTELTKKIELLEHLNCQ--IRQTNKELENKLATMGT 354 + E+ E+ + +L+ A L +L E +R+ +EL + Sbjct: 1447 KMS-ELEQLRELLLAQASALQNAESDRLRLNTQLEESQEEMKTLREEREELRRMQEALHV 1505 Query: 355 ESKAVSSPSKKGSPLISRKSGRN---TASKM--KSPWSQLSSETLNQDTDKKINKNEIAK 409 ES+ K+ S + + A K ++ S+ + LNQ + + + E + Sbjct: 1506 ESEQQKESMKEISSKLQELQNKEYECLAMKTINETQGSRCEMDHLNQQLEAQKSTLEKVE 1565 Query: 410 LEMV--IQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGP---- 463 +E V Q L++ L + V E+D +D L L+ + ME Sbjct: 1566 MENVNLTQRLHETLEEMRSVAKERDELWSMEERLTVERDQLKKSLEETVTKGMEKEEELR 1625 Query: 464 -SLIHVGTNTEDVNEIAKVQEQLKQELND---EIKDVN--VKDLIEKLKSAEEQITQLND 517 + +H+ + E +N++ K+ E++ ++K N V+ + L+ E Q++Q+ Sbjct: 1626 VAHVHLEEHQETINKLRKMVSDYTDEISHTQGDLKHTNAVVEAQNQDLREKEHQLSQVKA 1685 Query: 518 EIDAANKNMIKVKS-----NHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVA 572 ++ M ++K + L+ ++++K ++ +++++ K+I +T+E L Sbjct: 1686 DLRETVDQMEQLKKKLEAQSSTLESREIEK-LELTQQLNENLKKITLVTKENDSLKIMDE 1744 Query: 573 ELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHI 632 L EE+ L+ L ++ R +E+ ++ M NL E + L+E+ + +E+ Sbjct: 1745 ALREERDQLRKSLQQTEA-RDLENQEKLRIAHM-NLKEHQETIDRLMETMS-EKTEEISN 1801 Query: 633 LQQKYDEVEDKLAD-ISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDK-- 689 ++ + + V KL + + +L++ SE + V L+ KE L + ++++ Sbjct: 1802 MKMELENVNMKLQEKVQELKT----SERQRVKLKADASEAKKELKEQGLTLSKIEMENLN 1857 Query: 690 --EQLYGTIKDLENDKE--DIMNKLQNYIQENMD-LTDKLEKMSAEKISELLAKINHEEQ 744 ++++ ++++++ ++ D + KL+ ++ D L D L + + L A NHEE Sbjct: 1858 LAQKIHENLEEMKSVRKERDDLKKLEEILRMERDQLKDNLRE------AMLKAHQNHEET 1911 Query: 745 SKIQTQF-----GIDAKIQERDLYIENIESELSKYKSRI-CR------LEESIAVMEDRR 792 K +++E+ IE + S+ + C LE ++ Sbjct: 1912 MKCGKGLLCAGEYCTGRLREKCFRIEKLLKRYSEMANDYECLNKVSLDLERETKTQKELS 1971 Query: 793 YSLERKADQLGSYLQEKQK---AYSEYTIQEDELVNRLA-VLMDHDRVVEKQLLEIEHEN 848 ++ K + +E +K A +++ + RL VL R+ E+Q HE+ Sbjct: 1972 VTVRTKLSLPHTQTKEMEKLLTANQRCSLEFHRALKRLKYVLSSIARIKEEQ-----HES 2026 Query: 849 KELQKKNQILLEENQN-LQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDL-ESN 906 ++ I E QN LQI + + Q Y + + + L++ + L+D E++ Sbjct: 2027 INKREMAFIQEVEKQNELQIQIQSLSQTYR-IPARDLQIKLSQEMDLHIEEMLKDFSEND 2085 Query: 907 LKRITHEHQTLIVQKKKEIEDLEIEFNT-----QIESAIRDKK----VLNEKYEKNIEYV 957 I E Q ++ +K+ E L NT ++S I+ + ++N Y I + Sbjct: 2086 FLTIKTEVQQVLNNRKEITEFLGKWLNTLFDTENLKSTIQKENKSIGLVNNFYHSRITAM 2145 Query: 958 TQLEAQLQEYK-NNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNA 1016 + +E ++L+ ++ L + +L + + +QS + + + + Sbjct: 2146 INESTEFEERSATRSKDLDQYLKSLKETTEQLSEVYQTLTASQSVVHLHPTVQPSTRDSE 2205 Query: 1017 LLKQKD-EEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSK 1075 + E + KI V Y + D + +L + + + +E + L + Sbjct: 2206 RPQAASGAEQLTSKNKIALGAVPYKEEIEDLKMQLVKSDLEKKATAKEFDKKILSLKATV 2265 Query: 1076 QHNEELQILVREQDDQIKELKETKLTFEMN 1105 +H EE+ L+RE ++ ++T + E + Sbjct: 2266 EHQEEMIRLLRENLRGHQQAQDTSMISEQD 2295 Score = 68.9 bits (161), Expect = 1e-09 Identities = 207/1056 (19%), Positives = 451/1056 (42%), Gaps = 99/1056 (9%) Query: 305 EEKTEIEE-KGSLEIANMTELTKKI-ELLEHLNCQIRQTNKELENKLATMGTESKAVSSP 362 + +TE+ +G L + EL +K+ EL E R+ E + K++ + + + + Sbjct: 1403 QRETELSSVRGQLALTT-AELERKVQELCEKQEELTRKETSEAQGKMSELEQLRELLLA- 1460 Query: 363 SKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLN-KDL 421 + S L + +S R + SQ +TL ++ ++ E +E Q + K++ Sbjct: 1461 --QASALQNAESDRLRLNTQLEE-SQEEMKTLREEREELRRMQEALHVESEQQKESMKEI 1517 Query: 422 VDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEH-QQHMEGPSLIHVGTNTEDVNEIAK 480 K + K+ +T ++ +++H Q +E E+VN + Sbjct: 1518 SSKLQELQNKEYECLAMKTI---NETQGSRCEMDHLNQQLEAQKSTLEKVEMENVNLTQR 1574 Query: 481 VQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQ-LNDEIDAANKNMIKVKSNHKLKLKQ 539 + E L++ + + + + E+L +Q+ + L + + + +++ H + L++ Sbjct: 1575 LHETLEEMRSVAKERDELWSMEERLTVERDQLKKSLEETVTKGMEKEEELRVAH-VHLEE 1633 Query: 540 MQKTIDNFSK-VSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDV 598 Q+TI+ K VSD EI +L H + V E N L ++ + +++D+ Sbjct: 1634 HQETINKLRKMVSDYTDEISHTQGDLKHTNAVV-----EAQNQDLREKEHQLSQ-VKADL 1687 Query: 599 YKKMIEMENLAETRLKAISLLES---QKFDLVQELHILQQKYDEV---EDKLADISQLQS 652 + + +ME L + S LES +K +L Q+L+ +K V D L + + Sbjct: 1688 RETVDQMEQLKKKLEAQSSTLESREIEKLELTQQLNENLKKITLVTKENDSLKIMDEALR 1747 Query: 653 DQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQN 712 ++ KS+ E D + K +A + NLK +E + ++ + E+I N Sbjct: 1748 EERDQLRKSLQQTEARDLENQEKLRIAHM--NLKEHQETIDRLMETMSEKTEEISNMKME 1805 Query: 713 YIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGID-AKIQERDLYI-----EN 766 NM L +K++++ + + K + E K + G+ +KI+ +L + EN Sbjct: 1806 LENVNMKLQEKVQELKTSERQRVKLKADASEAKKELKEQGLTLSKIEMENLNLAQKIHEN 1865 Query: 767 IESELSKYKSR--ICRLEESIAVMEDR-RYSLERKADQLGSYLQEKQKA---------YS 814 +E S K R + +LEE + + D+ + +L + +E K Y Sbjct: 1866 LEEMKSVRKERDDLKKLEEILRMERDQLKDNLREAMLKAHQNHEETMKCGKGLLCAGEYC 1925 Query: 815 EYTIQE-----DELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISL 869 ++E ++L+ R + + + + K L++E E K QK+ L ++SL Sbjct: 1926 TGRLREKCFRIEKLLKRYSEMANDYECLNKVSLDLERETK-TQKE----LSVTVRTKLSL 1980 Query: 870 SDMQ-QHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHE-HQTLIVQKKKEIED 927 Q + L+ R L + K +L+ + S++ RI E H+++ ++ I++ Sbjct: 1981 PHTQTKEMEKLLTANQRCSLEFHRALK---RLKYVLSSIARIKEEQHESINKREMAFIQE 2037 Query: 928 LEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQL-QEYKNNIENLNMNVEELNKMNL 986 +E + QI+ + L++ Y L+ +L QE +IE + + E + + + Sbjct: 2038 VEKQNELQIQI-----QSLSQTYRIP---ARDLQIKLSQEMDLHIEEMLKDFSENDFLTI 2089 Query: 987 ELIDKHVQKQQTQSPDYTEQYIN---EINKLNALLKQKDEEIIALNQKINNAQVSYMSMV 1043 + + V + + ++ +++N + L + ++++++ I +N ++ + ++ Sbjct: 2090 KTEVQQVLNNRKEITEFLGKWLNTLFDTENLKSTIQKENKSIGLVNNFYHSRITAMINES 2149 Query: 1044 SDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFE 1103 +++E + A + L+ + ++ ++QL +E Q L Q + T + Sbjct: 2150 TEFEERSATRSKDLDQYLKSLKETTEQL------SEVYQTLTASQ-----SVVHLHPTVQ 2198 Query: 1104 MNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQE---- 1159 + +E +S E ++ N + LK+Q + +++++ +E Sbjct: 2199 PSTRDSERPQAASGAEQLT-SKNKIALGAVPYKEEIEDLKMQLVKSDLEKKATAKEFDKK 2257 Query: 1160 -QSAKLNTELQECYTKIIQLETLNTELTGHDV-VNQEQINQLKSKLEQLNTENDNLLSTV 1217 S K E QE ++++ E L D + EQ +QL SK + + ST Sbjct: 2258 ILSLKATVEHQEEMIRLLR-ENLRGHQQAQDTSMISEQDSQLLSKPLTCGGGSGIVQSTK 2316 Query: 1218 AELRSSISSAVDQRGFEIAELWKQHLAQREADFQ--KTEHELRVQLSAFESKYEQLLDSV 1275 A + + S + G EI++L +Q+ R+ + Q +L ++ +E + + DS Sbjct: 2317 ALI---LKSEYKRMGSEISKLKQQNEQLRKQNNQLLSDNSQLSNEVKTWEERTLK-RDSY 2372 Query: 1276 QSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQE 1311 + +T E + K + + S + + + +NLQ+ Sbjct: 2373 RETTCENSPKSPKVTRTDSKRRQNTTSQCRAQNLQD 2408 >UniRef50_Q9BJD3 Cluster: Major plasmodial myosin heavy chain; n=3; Physarum polycephalum|Rep: Major plasmodial myosin heavy chain - Physarum polycephalum (Slime mold) Length = 2148 Score = 130 bits (314), Expect = 3e-28 Identities = 266/1312 (20%), Positives = 538/1312 (41%), Gaps = 104/1312 (7%) Query: 147 LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXX 206 L +KE ++ ++ LQ +K + +++LQ+ + Q I + Sbjct: 872 LERQLKEAEHKIAQLQDSLKAEKANVVNLQDANADLKQEIATHERKIANLESELSEQTKL 931 Query: 207 XXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFE 266 K+ TK++E A++ E +D + L K D + +++ + Sbjct: 932 LDSITVARKEAETKVKELTTALQDE-RDARLNLEKAKRKVDDELDEVKKQHDFDVERIAN 990 Query: 267 ISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTK 326 + ++L E+E+ L KQ + + + ++E K + E+ TEL+K Sbjct: 991 LEKLKNELQAEVEELSDQFADETKSRASLEKQKRKIDSDLE-DLENKYNEEVTQRTELSK 1049 Query: 327 -KIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSP 385 K +L L Q E+E + G + K ++ + + + L + RN K K Sbjct: 1050 LKNQLDSDLRSTTSQLESEIERRGILEGLQKKLEAALASETAKLEEEQKNRNALEKAKKA 1109 Query: 386 WSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGK 445 Q + + D+K N++ K + L+ DL + + K G Sbjct: 1110 LEQQQRDLTQELQDEKKNRDTAEKAR---KKLDLDLTELRDQLDVK-----------GGD 1155 Query: 446 DTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELND---EIKDVNVK--D 500 +A L+ + +Q +E V + V+ + K++ L+ +LND + + N + + Sbjct: 1156 VKALADLKQKVEQELEDLRR-QVEELKKAVSNLEKIKRTLEAQLNDANNALAESNAENAN 1214 Query: 501 LIEKLKSAEEQITQLNDEIDAANKN---MIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEI 557 L + K EE + LN ++ ++ + K K +K+++ ++N S + + Sbjct: 1215 LTKLKKKLEEDLVALNQKLAEEQRDKAALDKAKKKADQDVKELKSNLENVSASRATLDQN 1274 Query: 558 VRLTEELHHLSQKVAELE-EEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAI 616 ++ TEE L ELE E+K QL + +++E++++ ++ + K Sbjct: 1275 LKATEE--KLENAKVELEQEQKTKQQLE----KAKKLLETELH----AVQGQLDDEKKGR 1324 Query: 617 SLLESQKFDLVQELHILQQKYDE---VEDKLADI-SQLQSDQVCSEIKSVHLEEQIDALS 672 +++ ++ DL EL L++ ++E + D S+LQSD E+K + + DA + Sbjct: 1325 DIVDRKRSDLESELADLREDFEEALSARKVIGDAKSKLQSDY--EELKKI---AESDAAA 1379 Query: 673 ASK-KELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKL--EKMSA 729 K +E ++E D + L ++D E E I + + + D+ +KL E+ + Sbjct: 1380 RQKAQEQVKILELQNADSQSL---VQDAEAAAEKIERQRRTLEADLQDVQEKLDEEQKAR 1436 Query: 730 EKISELLAKINHE-EQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVM 788 + + LAK + E Q+K++ + ++ + ++ ++ E S + L+E A Sbjct: 1437 VRFQKQLAKTDEELRQAKLKID-DLTNATSDQYIALKRLQEENSNQHRELEALDEKTAQW 1495 Query: 789 EDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHEN 848 R E + + L + L+E A + Q+ +L N++ D + + + + Sbjct: 1496 NRLRKQAEVQLEDLKAQLEEAISAKLKVEKQKRDLENKVE---DLESAADVNSANVHPD- 1551 Query: 849 KELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLK 908 EL+KK Q + E + Q++ ++ + V++ R D+ E + + E N Sbjct: 1552 -ELRKKQQEVDELKK--QLAAEQERKTKDEEVKRQLRKDVTTQEEA-----IEEYERN-- 1601 Query: 909 RITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYK 968 ++ E ++KK E E +++ + + E +R K L K + E T+++ + Sbjct: 1602 KLNAER----IRKKLENELEDLKASLESEQILRKKAELLAK-PRGKEGATEIKPTVSSKS 1656 Query: 969 NNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIAL 1028 + E+ EEL + EL +K + + E+ + N + L Q ++E+ A Sbjct: 1657 D--EDFKKLTEELAVLKTEL---DGEKAWRGNAEKRERALRAEN--DELRGQLEDEVTA- 1708 Query: 1029 NQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNE---ELQILV 1085 K N A+ + V + + +L + L+ EE +R +L + K+ E EL + + Sbjct: 1709 KDKTNKAKRALEVEVEELKDQLDEVEESLQEAEEFKRRKDLELEEVKRKLEGEAELTLKM 1768 Query: 1086 REQDDQI-KELKETKLTF-EMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLK 1143 E Q K+++ K+ E + E I +E +DD N K Sbjct: 1769 DELRKQFEKDIENLKVELEEERRSRGEAERIRKRLEAENDDLNIKLDAEIKTRQKTEKAK 1828 Query: 1144 VQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKL 1203 + E EF R+ L E+SA T+ + K+ + E ++V + I + + L Sbjct: 1829 KKIEGEFRATRTRLDEESA-TKTQSENLAQKLEEEIAKLKEDLDNEVKQKALIERTRKSL 1887 Query: 1204 EQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSA 1263 E + + A R++ Q E+ +L +Q A E + + R+++ Sbjct: 1888 ELQLEDTRTQMEVEARQRANADKLRRQAENELEDLREQVDAFDETEQDLLSDKTRLEVEC 1947 Query: 1264 FESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLR-NLQE-------KYAD 1315 E++ L +S ++ E + ++ L+ K D+E LR NL+ Y D Sbjct: 1948 EEARKNVLRES-EAREAAELARTRIQRELAELREK-YDEEVILRTNLERTRKKTDADYED 2005 Query: 1316 VINQIEI---LRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINE 1372 Q+E+ LR+++E E V L+ Q+ ++M E + Sbjct: 2006 AKEQLELESKLRAKLERE-VKAAAAGTKLLQTAKADADKLKARVQALEKM-EADYKKLQA 2063 Query: 1373 ENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLE--LKDSEIYQKTHE 1422 + + + +N+A A VL Q E D E +K++E Sbjct: 2064 RCTEEEDARRAAENEKKKAIADLNEARADVLFYQQQAEKIRTDVEKEKKSNE 2115 Score = 98.7 bits (235), Expect = 1e-18 Identities = 218/1102 (19%), Positives = 457/1102 (41%), Gaps = 85/1102 (7%) Query: 451 QLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNV-KDLIEKL-KSA 508 Q +LE E L N + + K EQ +++L E++D +D EK K Sbjct: 1079 QKKLEAALASETAKLEEEQKNRNALEKAKKALEQQQRDLTQELQDEKKNRDTAEKARKKL 1138 Query: 509 EEQITQLNDEIDAAN---KNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTE-EL 564 + +T+L D++D K + +K + +L+ +++ ++ K + ++I R E +L Sbjct: 1139 DLDLTELRDQLDVKGGDVKALADLKQKVEQELEDLRRQVEELKKAVSNLEKIKRTLEAQL 1198 Query: 565 HHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKF 624 + + +AE E NL + +E D+ + + E R KA L+ K Sbjct: 1199 NDANNALAESNAENANLT------KLKKKLEEDLVA--LNQKLAEEQRDKAA--LDKAKK 1248 Query: 625 DLVQELHILQQKYDEVEDKLADISQ-LQSDQVCSEIKSVHLEEQIDALSASKKELALVIE 683 Q++ L+ + V A + Q L++ + E V LE++ +K++L + Sbjct: 1249 KADQDVKELKSNLENVSASRATLDQNLKATEEKLENAKVELEQE----QKTKQQLEKAKK 1304 Query: 684 NLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEK-MSAEK-ISELLAKI-- 739 L+ + + G + D + ++ + K + E DL + E+ +SA K I + +K+ Sbjct: 1305 LLETELHAVQGQLDDEKKGRDIVDRKRSDLESELADLREDFEEALSARKVIGDAKSKLQS 1364 Query: 740 NHEEQSKI-QTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERK 798 ++EE KI ++ K QE+ ++ +E + + +S + E + +E +R +LE Sbjct: 1365 DYEELKKIAESDAAARQKAQEQ---VKILELQNADSQSLVQDAEAAAEKIERQRRTLEAD 1421 Query: 799 ADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQIL 858 + L E+QKA + Q LA + R + ++ ++ + + + L Sbjct: 1422 LQDVQEKLDEEQKARVRFQKQ-------LAKTDEELRQAKLKIDDLTNATSDQYIALKRL 1474 Query: 859 LEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLI 918 EEN N + AL EK + + ++ + QL DL++ L+ + Sbjct: 1475 QEENSN-------QHRELEALDEKTAQWNRLRKQA---EVQLEDLKAQLEEAISAKLKVE 1524 Query: 919 VQKK---KEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLN 975 QK+ ++EDLE + SA L +K ++ E QL A+ QE K E + Sbjct: 1525 KQKRDLENKVEDLESA--ADVNSANVHPDELRKKQQEVDELKKQLAAE-QERKTKDEEVK 1581 Query: 976 MNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLK-----QKDEEIIALNQ 1030 + + E I+++ ++ + + ++ NE+ L A L+ +K E++A + Sbjct: 1582 RQLRKDVTTQEEAIEEY-ERNKLNAERIRKKLENELEDLKASLESEQILRKKAELLAKPR 1640 Query: 1031 KINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDD 1090 A ++ S + + T +L ++ E+ + + E+ + +R ++D Sbjct: 1641 GKEGATEIKPTVSSKSDEDFKKLTEELAVLKTELDGEKAW----RGNAEKRERALRAEND 1696 Query: 1091 QIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEF 1150 +++ E ++T + K + + +E + D + V+ K E EE Sbjct: 1697 ELRGQLEDEVTAKDKTNKAK-RALEVEVEELKDQLDEVEESLQEAEEFKRR-KDLELEEV 1754 Query: 1151 IQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTEN 1210 ++ E + K++ EL++ + K +E L EL + ++ + +++ +LE EN Sbjct: 1755 KRKLEGEAELTLKMD-ELRKQFEK--DIENLKVELE-EERRSRGEAERIRKRLE---AEN 1807 Query: 1211 DNL-LSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHE-LRVQLSAFESKY 1268 D+L + AE+++ + ++ E E E KT+ E L +L +K Sbjct: 1808 DDLNIKLDAEIKTRQKTEKAKKKIE-GEFRATRTRLDEESATKTQSENLAQKLEEEIAKL 1866 Query: 1269 EQLLDSV--QSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSE 1326 ++ LD+ Q + E T K + + Q+ + +++ + N + N++E LR + Sbjct: 1867 KEDLDNEVKQKALIERTRKSLEL-QLEDTRTQMEVEARQRANADKLRRQAENELEDLREQ 1925 Query: 1327 IE--DEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXX 1384 ++ DE ++ E + I E A+L++ Sbjct: 1926 VDAFDETEQDLLSDKTRLEVECEEARKNVLRESEAREAAELARTRIQRELAELREKYDEE 1985 Query: 1385 XXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEY 1444 +A + QLEL +S++ K + + + Sbjct: 1986 VILRTNLERTRKKTDADYEDAKEQLEL-ESKLRAKLEREVKAAAAGTKLLQTAKADADKL 2044 Query: 1445 EKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQ 1504 + R++ L + E++ L+ + E E ++ +E E+ K I +LN + + +Q Sbjct: 2045 KARVQALE-KMEADYKKLQARCTEE----EDARRAAENEKKKAIADLNEARADVLFYQQQ 2099 Query: 1505 VAELNKALEEEVAKTNEMQTAL 1526 ++ +E+E ++Q L Sbjct: 2100 AEKIRTDVEKEKKSNEDLQANL 2121 Score = 95.1 bits (226), Expect = 1e-17 Identities = 203/994 (20%), Positives = 422/994 (42%), Gaps = 90/994 (9%) Query: 590 SGRMIESDVYKKMIEMENLAETRL--KAISLLESQKFDLVQELHILQQKYDEVEDKLADI 647 S R+I+ ++ + +E +N A +L KA LL + D +EL + ++ +LA Sbjct: 809 SARIIQDNI-RAYLEFKNWAWWKLFAKARPLLVGRNMD--KELKERDSQIKDLSSQLAAE 865 Query: 648 ----SQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDK 703 ++L+ +E K L++ + A A+ L +LK + I +LE++ Sbjct: 866 KAARAELERQLKEAEHKIAQLQDSLKAEKANVVNLQDANADLKQEIATHERKIANLESEL 925 Query: 704 EDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLY 763 + L + + K+++++ E A++N E+ +K + +D ++ D Sbjct: 926 SEQTKLLDSITVARKEAETKVKELTTALQDERDARLNLEK-AKRKVDDELDEVKKQHDFD 984 Query: 764 IE---NIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQE 820 +E N+E ++ ++ + L + A R SLE++ ++ S L++ + Y+E Q Sbjct: 985 VERIANLEKLKNELQAEVEELSDQFADETKSRASLEKQKRKIDSDLEDLENKYNEEVTQR 1044 Query: 821 DELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQIS-LSDMQQHYNAL 879 EL ++L +D D LE E E + + + Q LE + + L + Q++ NAL Sbjct: 1045 TEL-SKLKNQLDSDLRSTTSQLESEIERRGILEGLQKKLEAALASETAKLEEEQKNRNAL 1103 Query: 880 VEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEI--------- 930 EKA + E + +L+D + N + L + + + L++ Sbjct: 1104 -EKAKKA--LEQQQRDLTQELQDEKKNRDTAEKARKKLDLDLTELRDQLDVKGGDVKALA 1160 Query: 931 EFNTQIESAIRDKKVLNEKYEK---NIEYVTQ-LEAQLQEYKN-----NIENLNMN---- 977 + ++E + D + E+ +K N+E + + LEAQL + N N EN N+ Sbjct: 1161 DLKQKVEQELEDLRRQVEELKKAVSNLEKIKRTLEAQLNDANNALAESNAENANLTKLKK 1220 Query: 978 --VEELNKMNLELIDKH-----VQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQ 1030 E+L +N +L ++ + K + ++ ++ + + ++A D+ + A + Sbjct: 1221 KLEEDLVALNQKLAEEQRDKAALDKAKKKADQDVKELKSNLENVSASRATLDQNLKATEE 1280 Query: 1031 KINNAQVSYMSMVSDYESKLAQFTTKLEN-MEEEMQRVSKQLLDSKQHNEELQILVREQD 1089 K+ NA+V + E K Q K + +E E+ V QL D K+ + I+ R++ Sbjct: 1281 KLENAKVEL-----EQEQKTKQQLEKAKKLLETELHAVQGQLDDEKKGRD---IVDRKRS 1332 Query: 1090 DQIKELKETKLTFE--MNIPKTEG---MIISSTIEPMSDDANNVDXXXXXXXXXXXXLKV 1144 D EL + + FE ++ K G + S E + A + L++ Sbjct: 1333 DLESELADLREDFEEALSARKVIGDAKSKLQSDYEELKKIAESDAAARQKAQEQVKILEL 1392 Query: 1145 Q--EEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSK 1202 Q + + +Q+ E+ + L E + +Q E L+ E V Q+Q+ + + Sbjct: 1393 QNADSQSLVQDAEAAAEKIERQRRTL-EADLQDVQ-EKLDEEQKAR-VRFQKQLAKTDEE 1449 Query: 1203 LEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLS 1262 L Q + D+L + ++ ++ ++ + EL + L ++ A + + + VQL Sbjct: 1450 LRQAKLKIDDLTNATSDQYIALKRLQEENSNQHREL--EALDEKTAQWNRLRKQAEVQLE 1507 Query: 1263 AFESKYEQLLDS---VQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQ 1319 +++ E+ + + V+ ++ NK+ +E + N + LR Q++ ++ Q Sbjct: 1508 DLKAQLEEAISAKLKVEKQKRDLENKVEDLESAADV-NSANVHPDELRKKQQEVDELKKQ 1566 Query: 1320 IEILRS-EIEDEKVAFXXXXXXXXXXXXXXXXD---LRTENQSYKQMQEQSILNINEENA 1375 + + + +DE+V + L E K E L + E+ Sbjct: 1567 LAAEQERKTKDEEVKRQLRKDVTTQEEAIEEYERNKLNAERIRKKLENELEDLKASLESE 1626 Query: 1376 QL--KKSSXXXXXXXXXXXXRV-----NDAEAKVLELTHQLELKDSEI-YQKTHEYTITL 1427 Q+ KK+ + + ++ +LT +L + +E+ +K Sbjct: 1627 QILRKKAELLAKPRGKEGATEIKPTVSSKSDEDFKKLTEELAVLKTELDGEKAWRGNAEK 1686 Query: 1428 TQRNDEFEN--VRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHY-ETMQKESEIER 1484 +R EN +R QL E E +D T + + L + ++ + + E++Q+ E +R Sbjct: 1687 RERALRAENDELRGQL-EDEVTAKDKTNKAKRALEVEVEELKDQLDEVEESLQEAEEFKR 1745 Query: 1485 VK--LIEELNVKITESVSLNKQVAELNKALEEEV 1516 K +EE+ K+ L ++ EL K E+++ Sbjct: 1746 RKDLELEEVKRKLEGEAELTLKMDELRKQFEKDI 1779 Score = 87.8 bits (208), Expect = 2e-15 Identities = 149/786 (18%), Positives = 328/786 (41%), Gaps = 59/786 (7%) Query: 811 KAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLS 870 K E Q +L ++LA +E+QL E EH+ +LQ + NLQ + + Sbjct: 846 KELKERDSQIKDLSSQLAAEKAARAELERQLKEAEHKIAQLQDSLKAEKANVVNLQDANA 905 Query: 871 DMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEI 930 D++Q K + SE TK + + E T + ++ +LE Sbjct: 906 DLKQEIATHERKIANLESELSEQTKLLDSITVARKEAETKVKELTTALQDERDARLNLE- 964 Query: 931 EFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELID 990 + +++ + + K ++++ ++E + LE E + +E L+ + K L + Sbjct: 965 KAKRKVDDELDEVK---KQHDFDVERIANLEKLKNELQAEVEELSDQFADETKSRASL-E 1020 Query: 991 KHVQKQQTQSPDYTEQYINEINK---LNALLKQKDEEIIALNQKINNAQVSYMSMVSDYE 1047 K +K + D +Y E+ + L+ L Q D ++ + ++ + ++ ++ + Sbjct: 1021 KQKRKIDSDLEDLENKYNEEVTQRTELSKLKNQLDSDLRSTTSQLES-EIERRGILEGLQ 1079 Query: 1048 SKL-AQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNI 1106 KL A ++ +EEE Q+ L +K+ E+ Q R+ ++++ K+ + T E Sbjct: 1080 KKLEAALASETAKLEEE-QKNRNALEKAKKALEQQQ---RDLTQELQDEKKNRDTAEKAR 1135 Query: 1107 PKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNT 1166 K + + ++ + + +V KV++E E ++ R V + + A N Sbjct: 1136 KKLD-LDLTELRDQLDVKGGDVKALADLKQ------KVEQELEDLR-RQVEELKKAVSNL 1187 Query: 1167 ELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISS 1226 E + T QL N L + N + +LK KLE+ + L+ ++++ Sbjct: 1188 EKIK-RTLEAQLNDANNALAESNAENAN-LTKLKKKLEEDLVALNQKLAEEQRDKAALDK 1245 Query: 1227 AVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKI 1286 A + ++ EL K +L A + L+ E+ +L ++ Q E K Sbjct: 1246 AKKKADQDVKEL-KSNLENVSASRATLDQNLKATEEKLENAKVELEQEQKTKQQLEKAKK 1304 Query: 1287 VTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXX 1346 + ++ ++Q +L D+++ + K +D+ +++ LR + E+ A Sbjct: 1305 LLETELHAVQGQLDDEKKGRDIVDRKRSDLESELADLREDFEEALSA--------RKVIG 1356 Query: 1347 XXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELT 1406 L+++ + K++ E + Q+K V DAEA ++ Sbjct: 1357 DAKSKLQSDYEELKKIAESDAAARQKAQEQVK----ILELQNADSQSLVQDAEAAAEKIE 1412 Query: 1407 HQ---LELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILR 1463 Q LE ++ +K E + + ++L + + +I+DLT + L+ Sbjct: 1413 RQRRTLEADLQDVQEKLDEEQKARVRFQKQLAKTDEELRQAKLKIDDLTNATSDQYIALK 1472 Query: 1464 LKMHENANHYETM----QKESEIERVK-----LIEELNVKITESVSLNKQVAELNKALEE 1514 EN+N + + +K ++ R++ +E+L ++ E++S +V + + LE Sbjct: 1473 RLQEENSNQHRELEALDEKTAQWNRLRKQAEVQLEDLKAQLEEAISAKLKVEKQKRDLEN 1532 Query: 1515 EVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDN 1574 K ++++A + + DE+ Q V +++K ++ A ++ +DE++ Sbjct: 1533 ---KVEDLESAADVNSANVHP--DELRKKQQEV----DELKKQLA-AEQERKTKDEEVKR 1582 Query: 1575 TMNKEL 1580 + K++ Sbjct: 1583 QLRKDV 1588 Score = 86.6 bits (205), Expect = 5e-15 Identities = 235/1213 (19%), Positives = 492/1213 (40%), Gaps = 126/1213 (10%) Query: 143 DVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXX 202 +V LS+ ++ + + L+ + + +++ + DL+ K NE+ T Sbjct: 1001 EVEELSDQFADETKSRASLEKQKRKIDSDLEDLENKYNEE----------VTQRTELSKL 1050 Query: 203 XXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEA 262 T Q ++++ I + +++L + S+ ++ ++ LE Sbjct: 1051 KNQLDSDLRSTTSQLESEIERRGIL-----EGLQKKLEAALASETAKLEEEQKNRNALEK 1105 Query: 263 ARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEE-KTEIEEKGSLEIANM 321 A+ + + L QEL+ A++ ++ E + +++ KG ++ + Sbjct: 1106 AKKALEQQQRDLTQELQDEKKNRDTAEK-----ARKKLDLDLTELRDQLDVKGG-DVKAL 1159 Query: 322 TELTKKIEL-LEHLNCQIRQTNKELENKLATMGT-ESKAVSSPSKKGSPLISRKSGRNTA 379 +L +K+E LE L Q+ + K + N T E++ + + + Sbjct: 1160 ADLKQKVEQELEDLRRQVEELKKAVSNLEKIKRTLEAQLNDANNALAESNAENANLTKLK 1219 Query: 380 SKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXX 439 K++ L+ + + DK K + ++ L +L + + D Sbjct: 1220 KKLEEDLVALNQKLAEEQRDKAALDKAKKKADQDVKELKSNLENVSASRATLDQNLKATE 1279 Query: 440 XXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELND-EIKDVNV 498 + Q Q QQ + L+ E+ VQ QL E +I D Sbjct: 1280 EKLENAKVELEQEQKTKQQLEKAKKLLE--------TELHAVQGQLDDEKKGRDIVDRKR 1331 Query: 499 KDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIV 558 DL +L E +E +A K + KS + ++++K ++ + +E V Sbjct: 1332 SDLESELADLREDF----EEALSARKVIGDAKSKLQSDYEELKKIAESDAAARQKAQEQV 1387 Query: 559 RLTEELHHLSQKV---AELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKA 615 ++ E + SQ + AE EK Q ++ D DV +K+ E E A R + Sbjct: 1388 KILELQNADSQSLVQDAEAAAEKIERQRRTLEADL-----QDVQEKLDE-EQKARVRFQK 1441 Query: 616 ISLLESQKFDLVQELHILQQKYDEVEDKLAD----ISQLQSDQVCSEIKSVHLEEQIDAL 671 + K D +EL + K D++ + +D + +LQ + + L+E+ Sbjct: 1442 ----QLAKTD--EELRQAKLKIDDLTNATSDQYIALKRLQEENSNQHRELEALDEKTAQW 1495 Query: 672 SASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEK 731 + +K+ + +E+LK E+ +E K D+ NK++ DL + SA Sbjct: 1496 NRLRKQAEVQLEDLKAQLEEAISAKLKVEKQKRDLENKVE-------DLESAADVNSANV 1548 Query: 732 ISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDR 791 + L K +E +++ Q + QER E ++ +L K + EE+I E Sbjct: 1549 HPDELRK-KQQEVDELKKQLAAE---QERKTKDEEVKRQLRK---DVTTQEEAIEEYERN 1601 Query: 792 RYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKEL 851 + + ER +L + L++ + +++ ++++ + A L+ R E + + Sbjct: 1602 KLNAERIRKKLENELEDLKA-----SLESEQILRKKAELLAKPRGKEGATEIKPTVSSKS 1656 Query: 852 QKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRIT 911 + + L EE L+ L D ++ + EK R AE++ + + QL D E K T Sbjct: 1657 DEDFKKLTEELAVLKTEL-DGEKAWRGNAEKRERALRAEND--ELRGQLED-EVTAKDKT 1712 Query: 912 HEHQTLIVQKKKEIEDL--EIEFNTQIESAIRDKKVLN-EKYEKNIEYVTQLEAQLQE-- 966 ++ + + + +E++D E+E + Q + +K L E+ ++ +E +L ++ E Sbjct: 1713 NKAKRALEVEVEELKDQLDEVEESLQEAEEFKRRKDLELEEVKRKLEGEAELTLKMDELR 1772 Query: 967 --YKNNIENLNMNVEE--LNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKD 1022 ++ +IENL + +EE ++ E I K ++ + + I K K+ + Sbjct: 1773 KQFEKDIENLKVELEEERRSRGEAERIRKRLEAENDDLNIKLDAEIKTRQKTEKAKKKIE 1832 Query: 1023 EEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKL-ENMEEEMQRVSKQLLDSKQHNEEL 1081 E A +++ + + + KL + KL E+++ E+++ K L++ + + EL Sbjct: 1833 GEFRATRTRLDEESAT-KTQSENLAQKLEEEIAKLKEDLDNEVKQ--KALIERTRKSLEL 1889 Query: 1082 QILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXX 1141 Q+ + + E + N K + +E + + + D Sbjct: 1890 QL------EDTRTQMEVEARQRANADKLRRQ-AENELEDLREQVDAFDETEQDLLSDKTR 1942 Query: 1142 LKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKS 1201 L+V+ EE ++VL+E A+ EL T+I + E +V+ + + + + Sbjct: 1943 LEVECEE---ARKNVLRESEAREAAELAR--TRIQRELAELREKYDEEVILRTNLERTRK 1997 Query: 1202 KLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQL 1261 K + + L ++LR+ + +R + A + L +AD K + ++ L Sbjct: 1998 KTDADYEDAKEQLELESKLRAKL-----EREVKAAAAGTKLLQTAKADADKLKARVQA-L 2051 Query: 1262 SAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVI---N 1318 E+ Y++L Q+ EE + E +K++ + +L E ADV+ Sbjct: 2052 EKMEADYKKL----QARCTEEEDARRAAE---------NEKKKAIADLNEARADVLFYQQ 2098 Query: 1319 QIEILRSEIEDEK 1331 Q E +R+++E EK Sbjct: 2099 QAEKIRTDVEKEK 2111 >UniRef50_A0ECU5 Cluster: Chromosome undetermined scaffold_9, whole genome shotgun sequence; n=3; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_9, whole genome shotgun sequence - Paramecium tetraurelia Length = 1851 Score = 130 bits (314), Expect = 3e-28 Identities = 251/1278 (19%), Positives = 563/1278 (44%), Gaps = 109/1278 (8%) Query: 377 NTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXX 436 N + + + + E L QD K K I +L+ Q L K + + Y + +K Sbjct: 40 NLSGRKSTLFEDKRYEELLQDNRKL--KEVIEQLDKDNQQL-KQMSGESYNLKQKYMIAQ 96 Query: 437 XXXXXXXGK-DTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKD 495 + L +QL + + Q E +L V +DV+ + + Q Q +QE++ Sbjct: 97 AELEAAQQELAKLRSQLLMRNSQDAEQSTL--VTRYKQDVSTLTQQQIQYQQEISQ---- 150 Query: 496 VNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNK 555 + L+E+ + E+ +L + + + N +++++Q+++ + S + Sbjct: 151 --LNALLEQQRKQVEEFLRLKSKYEQDVQTYRSRAQNLEIEIRQVKE-----QRNSTTQN 203 Query: 556 EIVRLTEELHHLSQKVAELEEEKGNLQLHLVDY-DSGRMIESDVYKKMIEMENLAETRLK 614 EI+RLT+E+ +V +K + + D + +++D+ + +IE +N + +L+ Sbjct: 204 EIIRLTQEIARYQSEVQVRSSDKELYERTISTLNDKIKEMDNDI-QILIEAQNQNQYKLE 262 Query: 615 AI-----SLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQID 669 + S ++ Q L QE+ Q + + ++K + ++Q ++ SE + + +E +I+ Sbjct: 263 SAMAESKSNMQYQIDQLKQEMTFYQTQCKQWQEKCQTV-EMQKEE--SERRIIQMEIRIN 319 Query: 670 ALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTD----KLE 725 +KK++ +N K+ +E I ++N+ E K YI + + D +++ Sbjct: 320 E---TKKQIEQQ-QNDKVQRESYQ--IHTIQNELESWKQK---YISLEIKMKDYDNYRMQ 370 Query: 726 KMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERD----LYIENIES------ELSKYK 775 + E+ S N + + +++ ++QE++ L I +ES E +YK Sbjct: 371 LIQLEEQSNFYKNENDQMKEELEILIAEIKQLQEQNNGYRLSITQLESQARNSVENDRYK 430 Query: 776 SRICRLEESIAVMEDR--RYSLERKA-DQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMD 832 S+I LE +I + + Y +E K +Q Y Q K +++E +++L ++ Sbjct: 431 SQIRNLENTINQLNQQINAYKIETKELEQQVIYHQNKNTNVDYQVREKEETISKLQYKLN 490 Query: 833 HD----RVVEKQLLEIEHENKELQKKNQI---LLEENQNLQISLSDMQQHYNALVEKANR 885 + RV+ ++ L+IE ++ + QK+ QI L + + + +S ++QH+++L E N+ Sbjct: 491 NMEKELRVIFEEQLKIEKQDWDRQKQQQIDDQLQKITKKYESEISTLRQHFSSL-EIENQ 549 Query: 886 TDLAESESTKYQTQL---RDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRD 942 T + E K + ++ R E RI E + I+Q + ++ + EF+ +IE + Sbjct: 550 TLTKQYERLKKEGEMSFQRQSEKEKSRII-ELERQIIQLENQLSLQKKEFSLKIEEVNQS 608 Query: 943 K----------KVLNEKYEKNIEYVTQLEAQLQ-EYKNNIENLNMNVEELNKMNLELIDK 991 K +NEK ++ V QL QL E K +++ E+ + L+ DK Sbjct: 609 SNLKEYYEIQLKQINEKLQREQNQVKQLNEQLLIEQKKILDSETKYSREIRDIKLQQ-DK 667 Query: 992 HVQKQQ-TQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKL 1050 ++ QQ TQ E + ++ KL + ++E + ++ + + ++ + Sbjct: 668 RIEIQQNTQFQFEWENHQKDMEKLRREYRLIEQEYQEMEVQVKLWKEKFYDEQQKHQD-I 726 Query: 1051 AQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTE 1110 Q ++ + E V+ Q KQ +EL++ + + +Q++ + ++ I T Sbjct: 727 RQQLIEIRSQYESHTIVNTQSDYDKQRYQELEMEIIQLQEQMRLFSIREEKYKEQIT-TY 785 Query: 1111 GMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQE 1170 M I + DD + ++ ++ E +Q++S+ E KL + QE Sbjct: 786 SMTIEKQ-KSNFDDLKKIKHLEYEIESQR--IQYRDLERQLQDKSIEYE---KLLKKKQE 839 Query: 1171 CYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLL-STVAE---LRSSISS 1226 + I++ + + +L ++ +Q QI L+ +L+QLN+ ++ T+ E +RSS Sbjct: 840 VKLETIEISSNSDKLKIQELESQIQI--LRLQLQQLNSSKQEVIRETIRETVQVRSSEDI 897 Query: 1227 AVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLD-SVQSSTQEETNK 1285 + + E +LWK + + + E ++ + ES +++ + Q + + Sbjct: 898 KMIAQLEEELQLWKTKYYELDRRKNQVVVETIREVQSLESDKQRIQELEYQLQSLSSKKQ 957 Query: 1286 IVTMEQVT-SLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXX 1344 V E +T +++ L+ + +R L+ + +++ ++L S+ + E + Sbjct: 958 EVIREYITETIEVPLESDKLKIRQLETQLSNIQRDYQLL-SQKKQEVIQETITVEVPNQA 1016 Query: 1345 XXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLE 1404 L E+Q + QE ++++ ++ + + R+N + ++ Sbjct: 1017 DKYRIQQL--ESQLSQVRQELQVVSLKKQEVIKEIVTERIEVPMEQDRLRINHLQEQLSR 1074 Query: 1405 LTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRL 1464 L ++ D + Q+ + TIT+ + + + + +R Q ++E E +++L ++ Sbjct: 1075 LQRDYQILDQK-KQEVIKETITV-EVSSQADKLRIQ------QLESQLSELKTQLQLIIQ 1126 Query: 1465 KMHENANHYETMQKESEIERVKL-IEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQ 1523 K E T + E E K I +L +I LNK LNK +E + + ++ Sbjct: 1127 KKQEVIREIITERVEVSSEADKFRIRQLEQQIE---GLNKNYEILNKRKQEVITERITVE 1183 Query: 1524 TALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDA 1583 + +++I L +T L+ ++ SS+ Q+ + + Q+D ++L Sbjct: 1184 VPSQADKLKIQQLETLLTQLRQELQIVSSRKQEVIKEVVTERVEVPSQVDKLRIQQLEQQ 1243 Query: 1584 VPRAELDLAMYMLHQRDV 1601 + +L + ++++ Sbjct: 1244 LDNVRYELQILSQKKQEI 1261 Score = 130 bits (314), Expect = 3e-28 Identities = 277/1473 (18%), Positives = 612/1473 (41%), Gaps = 149/1473 (10%) Query: 212 EDTKQQMTKMQENFIAMEAE-WKDEKQRL---LKDIESKDVRISSLEEANKLLEAARFEI 267 ++ K Q Q + I E E WK + L +KD ++ +++ LEE + + ++ Sbjct: 329 QNDKVQRESYQIHTIQNELESWKQKYISLEIKMKDYDNYRMQLIQLEEQSNFYKNENDQM 388 Query: 268 SLEHSKLAQELEQXXXXXXXXXXXXXXL---AKQSIEPSCEEKTEIEE-KGSLEIANMTE 323 E L E++Q L A+ S+E K++I + ++ N Sbjct: 389 KEELEILIAEIKQLQEQNNGYRLSITQLESQARNSVEND-RYKSQIRNLENTINQLNQQI 447 Query: 324 LTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLIS--RKSGRNTASK 381 KIE E I NK N + + + +S K + + R Sbjct: 448 NAYKIETKELEQQVIYHQNKNT-NVDYQVREKEETISKLQYKLNNMEKELRVIFEEQLKI 506 Query: 382 MKSPWSQLSSETLNQDTDKKINK--NEIAKLEMVIQSLN--KDLVDKEYVISEKDTXXXX 437 K W + + ++ K K +EI+ L SL + K+Y +K+ Sbjct: 507 EKQDWDRQKQQQIDDQLQKITKKYESEISTLRQHFSSLEIENQTLTKQYERLKKEGEMSF 566 Query: 438 XXXXXXGKDTLIAQ----LQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEI 493 K +I +QLE+Q ++ E+VN+ + ++E Sbjct: 567 QRQSEKEKSRIIELERQIIQLENQLSLQKKEF---SLKIEEVNQSSNLKEYY-------- 615 Query: 494 KDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDS 553 ++ +K + EKL+ + Q+ QLN+++ K ++ ++ + +++ ++ D ++ + Sbjct: 616 -EIQLKQINEKLQREQNQVKQLNEQLLIEQKKILDSETKYSREIRDIKLQQDKRIEIQQN 674 Query: 554 NK---EIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAE 610 + E +++ L ++ +E+E +++ + ++ + Y + + +++ + Sbjct: 675 TQFQFEWENHQKDMEKLRREYRLIEQEYQEMEVQV------KLWKEKFYDEQQKHQDIRQ 728 Query: 611 TRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDA 670 ++ S ES Q + +Q+Y E+E +I QLQ I+ +EQI Sbjct: 729 QLIEIRSQYESHTIVNTQSDYD-KQRYQELE---MEIIQLQEQMRLFSIREEKYKEQITT 784 Query: 671 LSAS-------------KKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQEN 717 S + K L IE+ ++ L ++D + E ++ K Q E Sbjct: 785 YSMTIEKQKSNFDDLKKIKHLEYEIESQRIQYRDLERQLQDKSIEYEKLLKKKQEVKLET 844 Query: 718 MDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQE--RDLYIENIESELSKYK 775 ++++ +K+ KI EL ++I + ++Q Q +++ QE R+ E ++ S+ Sbjct: 845 IEISSNSDKL---KIQELESQI---QILRLQLQ-QLNSSKQEVIRETIRETVQVRSSEDI 897 Query: 776 SRICRLEESIAVMEDRRYSLERKADQ-LGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHD 834 I +LEE + + + + Y L+R+ +Q + ++E Q S+ + EL +L L Sbjct: 898 KMIAQLEEELQLWKTKYYELDRRKNQVVVETIREVQSLESDKQ-RIQELEYQLQSLSSKK 956 Query: 835 RVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEK----ANRTDLAE 890 + V ++ + E E+ ++ L + + L+ LS++Q+ Y L +K T E Sbjct: 957 QEVIREYIT---ETIEVPLESDKL--KIRQLETQLSNIQRDYQLLSQKKQEVIQETITVE 1011 Query: 891 SESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIE---------------FNTQ 935 + + +++ LES L ++ E Q + ++K++ I+++ E Q Sbjct: 1012 VPNQADKYRIQQLESQLSQVRQELQVVSLKKQEVIKEIVTERIEVPMEQDRLRINHLQEQ 1071 Query: 936 IESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQK 995 + RD ++L++K ++ I+ +E Q K I+ L + EL K L+LI +QK Sbjct: 1072 LSRLQRDYQILDQKKQEVIKETITVEVSSQADKLRIQQLESQLSEL-KTQLQLI---IQK 1127 Query: 996 QQTQSPDYTEQYINEINKLNAL-LKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFT 1054 +Q + + + ++ + ++Q +++I LN+ ++++ + T Sbjct: 1128 KQEVIREIITERVEVSSEADKFRIRQLEQQIEGLNKNYEILNKRKQEVITE------RIT 1181 Query: 1055 TKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMII 1114 ++ + ++++ + L Q +ELQI+ + + IKE+ ++ + K + Sbjct: 1182 VEVPSQADKLKIQQLETL-LTQLRQELQIVSSRKQEVIKEVVTERVEVPSQVDKLRIQQL 1240 Query: 1115 SSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSV-LQEQSAKLNTE---LQE 1170 ++ + + + +V+ E ++R + L+ KL + L + Sbjct: 1241 EQQLDNVRYELQILSQKKQEIIREVVTERVEVSRESDRKRILELESDLYKLQQDFINLNK 1300 Query: 1171 CYTKIIQLETLNTELTGH-DVVN----QEQINQLKSKLEQLNTENDNLLSTVAELRSSIS 1225 +++++ ET+ E+ D + Q++Q++S+L+ ++ + +++ R +S Sbjct: 1301 IKSEVVK-ETVTVEVPSQADKFRIQQLETQLSQVRSELQIVSAKKQDVIRETVTERIEVS 1359 Query: 1226 SAVD-----QRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYE-QLLDSVQSST 1279 S D Q ++ L + + + +K + L V++ + +Y + L+S SS Sbjct: 1360 SEQDKMRIRQLEQQLNSLQQDYFTLNQKKQEKIKETLTVEVPSETDRYRIRQLESQLSSL 1419 Query: 1280 QEETNKIVTMEQVTSLQNK-LQ----DKEEHLRNLQEKYAD------VINQIEILRSEIE 1328 +E+ N I Q +QNK LQ + ++ +R Q K + ++ Q E E+ Sbjct: 1420 KEDYNGIQVENQNLKIQNKSLQTTNYEYQDQVRIFQSKLEENSKQRSIVIQFERKEQELL 1479 Query: 1329 DEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKK-----SSXX 1383 ++ + L+ ENQ M + EE+ Q K+ S Sbjct: 1480 EQIQSLEAQKVREIKELKIQIEFLQKENQKINDMMRIKV----EESEQWKRKYQTVQSEM 1535 Query: 1384 XXXXXXXXXXRVNDAEAKVLELTHQLEL-KDSEIY-QKTHEYTITLTQRND---EFENVR 1438 R+ + T +LEL K +++Y Q +EYT ++ N+ + + Sbjct: 1536 SSNSSESESLRMQLKSLEQSRETIKLELDKVNKMYFQSQNEYTQYKSKCNELELRIKQIS 1595 Query: 1439 QQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITES 1498 ++ EY++R + + +EK S L + E E +Q +++ L +++ K + Sbjct: 1596 RENQEYQERYQQIDFEKISRLEQENRRKTETIQQLE-VQLRNQVSIKDLQSQISNKDKQI 1654 Query: 1499 VSLNKQVAELNKALEEEVAKTNEMQTALENQEIEI--VTLNDEITNLQNMVRASSSKIQK 1556 L + ++EL + + + Q++ + N +I L+ ++ + +IQ+ Sbjct: 1655 FQLQENISELQGTIRSLRVENQTISEQTNKQQVIVRETQNNQKIVELETRIQGLNQEIQR 1714 Query: 1557 HVSFASDTKQGRDEQLDNTMNKELLDAVPRAEL 1589 + + D+ ++ E + R EL Sbjct: 1715 QIQMKDQIQIKHDKLIERATEYESEINILRNEL 1747 Score = 72.1 bits (169), Expect = 1e-10 Identities = 115/650 (17%), Positives = 263/650 (40%), Gaps = 40/650 (6%) Query: 948 EKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQY 1007 EKY+ V + ++ + NN+ + E + L D K+ + D Q Sbjct: 20 EKYQTTSGIVASTDKRIVD--NNLSGRKSTLFEDKRYEELLQDNRKLKEVIEQLDKDNQQ 77 Query: 1008 INEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRV 1067 + +++ + LKQK A + S + S+ A+ +T + ++++ + Sbjct: 78 LKQMSGESYNLKQKYMIAQAELEAAQQELAKLRSQLLMRNSQDAEQSTLVTRYKQDVSTL 137 Query: 1068 SKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPM------ 1121 ++Q + +Q +L L+ +Q Q++E K +E ++ + IE Sbjct: 138 TQQQIQYQQEISQLNALLEQQRKQVEEFLRLKSKYEQDVQTYRSRAQNLEIEIRQVKEQR 197 Query: 1122 -SDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSV--LQEQSAKLNTELQECYTKIIQL 1178 S N + ++V+ ++ + ER++ L ++ +++ ++Q Q Sbjct: 198 NSTTQNEIIRLTQEIARYQSEVQVRSSDKELYERTISTLNDKIKEMDNDIQILIEAQNQN 257 Query: 1179 E-TLNTELTGHDVVNQEQINQLKSKLEQLNTEN---DNLLSTVAELRSSISSAVDQRGFE 1234 + L + + Q QI+QLK ++ T+ TV + + Q Sbjct: 258 QYKLESAMAESKSNMQYQIDQLKQEMTFYQTQCKQWQEKCQTVEMQKEESERRIIQMEIR 317 Query: 1235 IAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTS 1294 I E KQ Q+ Q+ +++ + ES ++Q S++ ++ N + + Q+ Sbjct: 318 INETKKQIEQQQNDKVQRESYQIHTIQNELES-WKQKYISLEIKMKDYDNYRMQLIQLEE 376 Query: 1295 LQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXX--XDL 1352 N +++ + ++ E+ +I +I+ L+ + +++ + Sbjct: 377 QSNFYKNENDQMK---EELEILIAEIKQLQEQNNGYRLSITQLESQARNSVENDRYKSQI 433 Query: 1353 RTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELK 1412 R + Q+ +Q I E +L++ +V + E + +L ++L Sbjct: 434 RNLENTINQLNQQ-INAYKIETKELEQQVIYHQNKNTNVDYQVREKEETISKLQYKLNNM 492 Query: 1413 DSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMH----E 1468 + E+ E L +++ +QQ ++ +++ +T + ESE++ LR E Sbjct: 493 EKELRVIFEEQ---LKIEKQDWDRQKQQQID--DQLQKITKKYESEISTLRQHFSSLEIE 547 Query: 1469 N---ANHYETMQKESEIERVKLIEELNVKITES----VSLNKQVAELNKALEEEVAKTNE 1521 N YE ++KE E+ + E+ +I E + L Q++ K ++ + N+ Sbjct: 548 NQTLTKQYERLKKEGEMSFQRQSEKEKSRIIELERQIIQLENQLSLQKKEFSLKIEEVNQ 607 Query: 1522 MQTALENQEIEIVTLNDEITNLQNMVRASSSK--IQKHVSFASDTKQGRD 1569 E EI++ +N+++ QN V+ + + I++ S+TK R+ Sbjct: 608 SSNLKEYYEIQLKQINEKLQREQNQVKQLNEQLLIEQKKILDSETKYSRE 657 >UniRef50_A0BTE2 Cluster: Chromosome undetermined scaffold_127, whole genome shotgun sequence; n=3; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_127, whole genome shotgun sequence - Paramecium tetraurelia Length = 1858 Score = 130 bits (313), Expect = 4e-28 Identities = 280/1367 (20%), Positives = 594/1367 (43%), Gaps = 152/1367 (11%) Query: 218 MTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHS---KL 274 M + N A+E E E R+ KD K++ + ++ K +E R EISL+ S KL Sbjct: 1 MQSLAGNKEAIEKELSLE--RVAKDGLKKEILQITNQQKIKDMEL-RNEISLKSSEIIKL 57 Query: 275 AQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHL 334 +E E+ + +Q+ + + +++EK LEI+ K+IE+ L Sbjct: 58 NKEAERLDGLFKQATLELKRINEQNEDLRLIDDFQLKEK-DLEISKF----KQIEI--EL 110 Query: 335 NCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETL 394 +I+Q K+L N+ + E+ + K + +S + R K ++ + L Sbjct: 111 KNRIQQLQKQLSNQEWQLSQENIKLKQQVKDLNNDVSILNTRVNMLKTQNKDESERFQEL 170 Query: 395 NQDTDKKINK--NEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQL 452 Q D ++ + I+++ + L + K+ D L Q Sbjct: 171 LQSHDVELQSWADRYKDQSQQIETMAQQLFAAQQQNKYKEQLIFEYDKLKQEFDLLNRQY 230 Query: 453 QLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVN-VKDLIEKLKSAEEQ 511 Q + + + + N ++V E+ ++QE +Q++ K+++ ++D L+ + Sbjct: 231 QSLQENSLRNSN---IKENAKNV-EMQQLQEHYEQQVVQLQKEIDFMRDNKVNLRQ-DAS 285 Query: 512 ITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKV 571 + + +I A N + VK N+++ +MQ + + + +I+ L E+L L KV Sbjct: 286 VIDFSVQITALNDQL--VKKNNEITNIRMQAN----RTIMEKDNQIILLQEQLEQLISKV 339 Query: 572 AELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELH 631 +E + + + ++ +I ++ K +++++ + + + Q ++ ++L Sbjct: 340 DIIENNQNDQAEAIEKAENLELIMNEKDKFIVQLK-------EELQNCKDQILEMEEQLK 392 Query: 632 ILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQ 691 I Q D ++ + + IS+L+S +++ +E Q K ++++ + Sbjct: 393 IRQNSLDMIQQQASLISELKS-----QVERRQIENQTGV--QPKPVQQCFTKSIRSSTHR 445 Query: 692 LYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQF 751 + G K +N +E ++ +Y+Q+ D++ K ++ + + IS + +I+ +Q Q+Q Sbjct: 446 MSG--KKSQNIEES-QKEIISYVQKVTDVSFK-QQSNQQIISIVNPQISETKQILRQSQ- 500 Query: 752 GIDAKIQERDLYIENI---ESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQE 808 ++Q+R+L ++I + EL + K + +++ + + K +QL Q Sbjct: 501 ---EELQQRNLLNQSIMVLQQELKQVKLNLSNEQQASSQLRFELSQANAKIEQL----QL 553 Query: 809 KQKAYSEYTIQEDEL-VNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQI 867 +Q + Q D + V+RL + K + Q L E Q+LQ Sbjct: 554 EQSQLKNKSQQNDSINVDRLNTM----------------SMKTYESNMQSLKSEKQDLQQ 597 Query: 868 SLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIED 927 L + +Q + + N ++E K + Q++ L + ++ + I + K I+ Sbjct: 598 KLIEQEQQFTTFTSRINEL---QNEIKKQKEQIQQLNDS----ENQKENQIFEYKSIIDR 650 Query: 928 LEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQ-LEAQLQEYKNNIENLNMNVEELNKMNL 986 L+ ++ +S +R K+ ++ E + Q L+ + QE K N L+ K+ L Sbjct: 651 LQNNLKSE-QSIVRQKQSEVKQITYQQEQIQQMLQQEYQEIKKNNNELSQQ-----KLKL 704 Query: 987 ELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDY 1046 EL + ++ Q QS + Y ++I KLN+ + E++ QK + + + Sbjct: 705 ELEIQELKSQLQQSQVNQQFYESKITKLNSEILLVREKLGKFEQKTIQIEQTKTQSSQNS 764 Query: 1047 ESKLAQFTTKLENMEEEMQRVSKQL--LDSKQHNEELQILVREQDDQIKELKETKLTFEM 1104 + +QF +++ + +++R +QL L+ ++ N +LQIL + D I + + + + Sbjct: 765 DQLQSQFQQQIQELTSKLER-QQQLSNLNQQELNNQLQILKEQYQDTIFKFENS----QE 819 Query: 1105 NIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKL 1164 + + + + ++D N LK+Q E Q+ S +E Sbjct: 820 QVKLLQNSLAQQKQQYLNDMNENAQ-MLSITNQENQNLKIQ-IEHLNQQLSAYKES---- 873 Query: 1165 NTELQECYTKIIQLETLNTE--LTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAE--- 1219 NT +Q+ +++ QL+ E L D+ NQ Q NQL + +Q E +L+ + E Sbjct: 874 NTNVQKWQSQVDQLQKQLREDKLQQQDLNNQLQ-NQL-FQFQQSKREWQDLIQRLQEDNN 931 Query: 1220 -LRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFES--KYEQLLDSVQ 1276 L+++++ + R + E + Q+ + Q T + ++ Q + S E++L +Q Sbjct: 932 QLQANLNRVLTARSEK--EQIDNYTHQQNQNIQITTNTIKTQFMSNTSGMSSEKILIELQ 989 Query: 1277 SSTQEETNKIVTMEQVTSLQNK-----LQDKEEHLRNLQEKYADVINQIEILR----SEI 1327 + QEE K+++ QV L NK +QD +E R L+ +Y + +I++ +I Sbjct: 990 IA-QEENVKLISQLQVLQLNNKQLNKEIQDFDEKQRQLENRYKEQYLRIQLEHDLSFKKI 1048 Query: 1328 EDEKV-------AFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKS 1380 E E V + + N Q+Q Q +L + ++N+ K Sbjct: 1049 EQENVKLISQVEVYQKKQQQQEILIDDYIAQIEKLNIINNQLQSQLLL-VQKDNSNFYKD 1107 Query: 1381 SXXXXXXXXXXXXRV--NDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVR 1438 ++ + + T QL++KD + ++T E L+Q ++E ++ Sbjct: 1108 QDKQIYRLSEINQQLLTQITQLNNQKNTDQLQIKDLIVIKQTLEE--QLSQHSEEIFSLN 1165 Query: 1439 QQLVEYEKRIEDLTYEK----------ESELAILRLK----MHENANHYETMQ-KESEIE 1483 ++L + + LT+ +++L+ L++K ++EN + Q ++S Sbjct: 1166 ERLKDLSDQNTQLTHMNSGYLNQITGLQAQLSELQIKFTQNIYENKPRFSDQQPRQSTSS 1225 Query: 1484 RVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQE 1530 + IEELN KI +SLN QV LN+ + + ++ L+N++ Sbjct: 1226 NSRQIEELNNKI---ISLNNQVNILNQQKSQIQQELISVRKQLQNEQ 1269 Score = 129 bits (312), Expect = 5e-28 Identities = 291/1476 (19%), Positives = 594/1476 (40%), Gaps = 136/1476 (9%) Query: 161 LQVKMKIMETTILDLQEKI-NEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMT 219 L++ M + I+ L+E++ N KDQI+E + + + K Q+ Sbjct: 359 LELIMNEKDKFIVQLKEELQNCKDQILEMEEQLKIRQNSLDMIQQQASLIS--ELKSQVE 416 Query: 220 KMQ-ENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQEL 278 + Q EN ++ K +Q K I S R+S + N +E ++ EI K+ Sbjct: 417 RRQIENQTGVQP--KPVQQCFTKSIRSSTHRMSGKKSQN--IEESQKEIISYVQKVTDVS 472 Query: 279 --EQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTK-KIELL--EH 333 +Q KQ + S EE + + EL + K+ L + Sbjct: 473 FKQQSNQQIISIVNPQISETKQILRQSQEELQQRNLLNQSIMVLQQELKQVKLNLSNEQQ 532 Query: 334 LNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPL-------ISRKSGRNTASKMKSPW 386 + Q+R + K+ + E + + S++ + +S K+ + +KS Sbjct: 533 ASSQLRFELSQANAKIEQLQLEQSQLKNKSQQNDSINVDRLNTMSMKTYESNMQSLKSEK 592 Query: 387 SQLSSETLNQDTD-----KKINK--NEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXX 439 L + + Q+ +IN+ NEI K + IQ LN KE I E + Sbjct: 593 QDLQQKLIEQEQQFTTFTSRINELQNEIKKQKEQIQQLNDSENQKENQIFEYKSIIDRLQ 652 Query: 440 XXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQE-LNDEIKDVNV 498 + +++ Q Q E +Q I E EI K +L Q+ L E++ + Sbjct: 653 NNLKSEQSIVRQKQSEVKQITYQQEQIQQMLQQE-YQEIKKNNNELSQQKLKLELEIQEL 711 Query: 499 KDLIEKLKSA----EEQITQLNDEIDAANKNMIKVKSNH-KLKLKQMQKTIDNFSKVSDS 553 K +++ + E +IT+LN EI + + K + +++ + Q + ++ S Sbjct: 712 KSQLQQSQVNQQFYESKITKLNSEILLVREKLGKFEQKTIQIEQTKTQSSQNSDQLQSQF 771 Query: 554 NKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVD---YDSGRMIESDVYKKMIEMENLAE 610 ++I LT +L Q+++ L +++ N QL ++ D+ E+ + + +LA+ Sbjct: 772 QQQIQELTSKLER-QQQLSNLNQQELNNQLQILKEQYQDTIFKFENSQEQVKLLQNSLAQ 830 Query: 611 TRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDA 670 + + ++ + Q L I Q+ ++ ++ ++Q S S + Q+D Sbjct: 831 QKQQYLNDMNEN----AQMLSITNQENQNLKIQIEHLNQQLSAYKESNTNVQKWQSQVDQ 886 Query: 671 LSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEK-MSA 729 L +E L ++L QL + + K + + +Q ++N L L + ++A Sbjct: 887 LQKQLREDKLQQQDLN---NQLQNQLFQFQQSKREWQDLIQRLQEDNNQLQANLNRVLTA 943 Query: 730 EKISELLAKINHEEQSKIQ-TQFGIDAKIQERD--LYIENIESELSKYKSRICRLEESIA 786 E + H++ IQ T I + + E I EL + +L + Sbjct: 944 RSEKEQIDNYTHQQNQNIQITTNTIKTQFMSNTSGMSSEKILIELQIAQEENVKLISQLQ 1003 Query: 787 VMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEH 846 V++ L ++ ++ + Y E L + ++HD +K IE Sbjct: 1004 VLQLNNKQLNKEIQDFDEKQRQLENRYKE---------QYLRIQLEHDLSFKK----IEQ 1050 Query: 847 ENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANR-TDLAESESTKYQTQ----LR 901 EN +L + ++ ++ Q +I + D Y A +EK N + +S+ Q + Sbjct: 1051 ENVKLISQVEVYQKKQQQQEILIDD----YIAQIEKLNIINNQLQSQLLLVQKDNSNFYK 1106 Query: 902 DLESNLKRITHEHQTLIVQKKKEIEDLEIEFNT---QIESAIRDKKVLNEKYEKNIEYVT 958 D + + R++ +Q L+ Q I L + NT QI+ I K+ L E+ ++ E + Sbjct: 1107 DQDKQIYRLSEINQQLLTQ----ITQLNNQKNTDQLQIKDLIVIKQTLEEQLSQHSEEIF 1162 Query: 959 QLEAQLQEYKN-NIENLNMNVEELNKMN------LELIDKHVQKQQTQSPDYTEQYINEI 1011 L +L++ + N + +MN LN++ EL K Q P +++Q + Sbjct: 1163 SLNERLKDLSDQNTQLTHMNSGYLNQITGLQAQLSELQIKFTQNIYENKPRFSDQQPRQS 1222 Query: 1012 NKLNAL-LKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQ 1070 N+ +++ + +II+LN ++N S + +L +L+N +++ R S+Q Sbjct: 1223 TSSNSRQIEELNNKIISLNNQVNILN----QQKSQIQQELISVRKQLQNEQDD--RFSQQ 1276 Query: 1071 LLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDX 1130 S+Q+ + E +++I++L++ ++ + + M + NN Sbjct: 1277 ---SRQNRSNQYKVASEMEERIRQLQQQLEEEKLGKFSNNSEVELKNKQIMILEQNN--- 1330 Query: 1131 XXXXXXXXXXXLKVQEEEEFI-QERSVLQEQSAK---LNTELQ--ECYTKIIQLETLNTE 1184 L+++EE+ + +E L EQ+ + L T E + Q E+L E Sbjct: 1331 KKLQQQLEQLNLQIEEEKSLLYKEIDQLSEQNKRTKQLKTSEYDIEFRNSVKQSESLKQE 1390 Query: 1185 LTGHDVVNQEQINQLKSKLEQLNTENDNLLST------VAELRSSISSAVDQRGFEIAEL 1238 L + ++Q +++ + +Q+ +N+ + + EL + + EI EL Sbjct: 1391 LLQANQTIKKQQSRIATLEDQITKQNNGSIDMDRQNRFILELEEKLKGNQRKYEIEIKEL 1450 Query: 1239 WKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTS-LQN 1297 K +K ++EL+ S + + E+ +Q Q + ++ S L+ Sbjct: 1451 -KNDKQSLNQQLEKAQYELQEIKSKYHIELEKTEQKLQKENQRFSLQLNDKAAYLSQLEV 1509 Query: 1298 KLQDKEEHLRNLQEKYADVINQI-EILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTEN 1356 K + +E + N QE+Y + + Q E ++ ED ++ +N Sbjct: 1510 KNRQLKEEILNQQERYDEKLRQANERIKEVTEDLEIMIDNYKKEKQLSQKW-----ERQN 1564 Query: 1357 QSYKQMQEQSI--LNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDS 1414 + ++ + S+ + I E ++K ++ L + LK+ Sbjct: 1565 EDLRRQLQSSVDDVKIKTERLSVEKYERMSLDSRKQIEQVQQQLNNEINGLKQDIRLKNE 1624 Query: 1415 EIYQKTHEYTITLTQRNDEFE----NVRQQLVEY----EKRIEDLTYEKESELA-ILRLK 1465 +I Q +L Q+ +FE ++ QL ++ E+ + DL K LA L +K Sbjct: 1625 QINQ-LKSTNQSLQQKLSKFETYIRDLEDQLQQFSNKEEQLLRDLNQSKNQSLADSLNVK 1683 Query: 1466 MHENANHY-ETMQKESEI-ERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQ 1523 + N+ + Q+E ++ ++++ +E + + N EE + Sbjct: 1684 VMALENNLVKAQQREDQLLQKIRQLENQQNSFRNNSDYRNLEVKNNNMFEE----IQILV 1739 Query: 1524 TALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVS 1559 ++NQ+ EI TL +E+T+ Q V +++ S Sbjct: 1740 QTIKNQDQEIATLKNELTSYQREVSFMKEVVKEDTS 1775 Score = 124 bits (298), Expect = 3e-26 Identities = 244/1100 (22%), Positives = 477/1100 (43%), Gaps = 118/1100 (10%) Query: 176 QEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQ-MTKMQENFIAMEAEWKD 234 Q+++N + QI++ + + T KQQ + M EN M + Sbjct: 793 QQELNNQLQILKEQYQDTIFKFENSQEQVKLLQNSLAQQKQQYLNDMNEN-AQMLSITNQ 851 Query: 235 EKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXX 294 E Q L IE + ++S+ +E+N ++ + ++ +L ++ Q Sbjct: 852 ENQNLKIQIEHLNQQLSAYKESNTNVQKWQSQVDQLQKQLREDKLQQQDLNNQLQNQLFQ 911 Query: 295 LAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGT 354 + E + E+ L+ AN+ + E ++ Q N+ ++ T+ T Sbjct: 912 FQQSKREWQDLIQRLQEDNNQLQ-ANLNRVLTARSEKEQIDNYTHQQNQNIQITTNTIKT 970 Query: 355 ESKAVSSPSKKGSPLISRKSGRNTASKMKSPWS--QLSSETLN---QDTDKKINKNEIAK 409 + + +S LI + + K+ S QL+++ LN QD D+K + E Sbjct: 971 QFMSNTSGMSSEKILIELQIAQEENVKLISQLQVLQLNNKQLNKEIQDFDEKQRQLENRY 1030 Query: 410 LEMVIQ-SLNKDL----VDKEYV--ISEKDTXXXXXXXXXXGKDTLIAQLQLEH--QQHM 460 E ++ L DL +++E V IS+ + D IAQ++ + + Sbjct: 1031 KEQYLRIQLEHDLSFKKIEQENVKLISQVEVYQKKQQQQEILIDDYIAQIEKLNIINNQL 1090 Query: 461 EGPSLIHVGTNT-------EDVNEIAKVQEQLKQEL----NDEIKD-VNVKDLIEKLKSA 508 + L+ N+ + + ++++ +QL ++ N + D + +KDLI ++ Sbjct: 1091 QSQLLLVQKDNSNFYKDQDKQIYRLSEINQQLLTQITQLNNQKNTDQLQIKDLIVIKQTL 1150 Query: 509 EEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLS 568 EEQ++Q ++EI + N+ + K S+ +L M N ++ +L+E + Sbjct: 1151 EEQLSQHSEEIFSLNERL-KDLSDQNTQLTHM-----NSGYLNQITGLQAQLSELQIKFT 1204 Query: 569 QKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQ 628 Q + E + + Q + R IE ++ K+I + N +++L QK + Q Sbjct: 1205 QNIYENKPRFSDQQPRQSTSSNSRQIE-ELNNKIISLNN-------QVNILNQQKSQIQQ 1256 Query: 629 EL-HILQQKYDEVEDKLADIS-QLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLK 686 EL + +Q +E +D+ + S Q +S+Q ++ S +EE+I L +E L + Sbjct: 1257 ELISVRKQLQNEQDDRFSQQSRQNRSNQY--KVAS-EMEERIRQLQQQLEEEKLGKFSNN 1313 Query: 687 LDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAE--KISELLAKINHEEQ 744 + E I LE + + + +L+ Q N+ + ++ + E ++SE + + Sbjct: 1314 SEVELKNKQIMILEQNNKKLQQQLE---QLNLQIEEEKSLLYKEIDQLSEQNKRTKQLKT 1370 Query: 745 SKIQTQFGIDAKIQERDLYIENIESE--LSKYKSRICRLEESIAVMEDRRYSLERKADQL 802 S+ +F K Q L E +++ + K +SRI LE+ I + ++R+ ++ Sbjct: 1371 SEYDIEFRNSVK-QSESLKQELLQANQTIKKQQSRIATLEDQITKQNNGSIDMDRQ-NRF 1428 Query: 803 GSYLQEKQKAYS-EYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHE-NKELQKKNQILLE 860 L+EK K +Y I+ EL N L + +L EI+ + + EL+K Q L + Sbjct: 1429 ILELEEKLKGNQRKYEIEIKELKNDKQSLNQQLEKAQYELQEIKSKYHIELEKTEQKLQK 1488 Query: 861 ENQNLQISLSDMQQHYNALVEKANRTDLAE--SESTKYQTQLRDLESNLKRITHEHQTLI 918 ENQ + L+D + + L E NR E ++ +Y +LR +K +T + + +I Sbjct: 1489 ENQRFSLQLNDKAAYLSQL-EVKNRQLKEEILNQQERYDEKLRQANERIKEVTEDLEIMI 1547 Query: 919 VQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEK-NIEYVTQLEAQLQEYKNNIENLNMN 977 KKE K L++K+E+ N + QL++ + + K E L+ Sbjct: 1548 DNYKKE-------------------KQLSQKWERQNEDLRRQLQSSVDDVKIKTERLS-- 1586 Query: 978 VEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIAL---NQKINN 1034 VE+ +M+L D Q +Q Q +Q NEIN L ++ K+E+I L NQ + Sbjct: 1587 VEKYERMSL---DSRKQIEQVQ-----QQLNNEINGLKQDIRLKNEQINQLKSTNQSLQQ 1638 Query: 1035 AQVSYMSMVSDYESKLAQFTTKLENMEEEM-QRVSKQLLDSKQHN----EELQILVREQD 1089 + + + D E +L QF+ K E + ++ Q ++ L DS E + ++++ Sbjct: 1639 KLSKFETYIRDLEDQLQQFSNKEEQLLRDLNQSKNQSLADSLNVKVMALENNLVKAQQRE 1698 Query: 1090 DQ----IKELKETKLTFEMNIP----KTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXX 1141 DQ I++L+ + +F N + + + I+ + N D Sbjct: 1699 DQLLQKIRQLENQQNSFRNNSDYRNLEVKNNNMFEEIQILVQTIKNQDQEIATLKNELT- 1757 Query: 1142 LKVQEEEEFIQERSVLQEQSAKLNTE--LQECYTKIIQLET----LNTELTGHDVVNQEQ 1195 Q E F++E V++E +++L T L + +I++LE L E T + + +Q Sbjct: 1758 -SYQREVSFMKE--VVKEDTSRLETSSVLDDKNRRIVELENKCALLANENTRLNQLKVKQ 1814 Query: 1196 INQLKSKLEQLNTENDNLLS 1215 +++ K K ++L E + L+ Sbjct: 1815 VDEWKVKYDKLQQELEKSLN 1834 >UniRef50_Q7RIN9 Cluster: Putative uncharacterized protein PY03578; n=8; Plasmodium (Vinckeia)|Rep: Putative uncharacterized protein PY03578 - Plasmodium yoelii yoelii Length = 1527 Score = 129 bits (312), Expect = 5e-28 Identities = 251/1236 (20%), Positives = 536/1236 (43%), Gaps = 129/1236 (10%) Query: 89 GISESLANTLKQ-KEILMEKIKQYKELS----KRSSTTIVRXXXXXXXXXXXXXXXQLGD 143 G+ E+L N K+ K I M+ + +S KR+STT+VR ++ Sbjct: 347 GVIENLENKNKEIKRISMDNFEFNNPISNHINKRNSTTVVRSVFNPQLEYNNVENNEIRK 406 Query: 144 VTHLSNTIKEKDNALSVLQVKMKIMET-TILDLQEKINEKDQIIEAK---NKATTXXXXX 199 + N +L + K++E + + NE I K +K T+ Sbjct: 407 FNTIGNNYMNIGRENDILNISPKVIEKINRRNTHQLFNESSNISTDKLTIHKVTSPFLFD 466 Query: 200 XXXXXXXXXXXXE----DTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEE 255 E K + + E ME K EK + +E + ++S Sbjct: 467 NINNDSNTNVSNEIPEKGGKMEKVEKMEKMEKMEKMEKVEKMEEFEKMEKSNEHVNSFSM 526 Query: 256 ANK----LLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIE 311 N +E+ I+++ + + L Q+I + K + + Sbjct: 527 FNLDKGVSVESTSNIIAMDENPIILNDSNTINKNNIIDAESDKLV-QNILDMIKIKLQDD 585 Query: 312 EKGSLE--IAN--------MTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSS 361 K +++ I N + E T +E+L + CQ+++ N+++E+K T+ E+ ++ Sbjct: 586 NKNNIDTIIKNESKRITSLLEEKTGSMEILCNKICQLKKKNEDVEDKNDTIREETHQINI 645 Query: 362 PSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDL 421 K + + + N +K + + + N K+ +EI + +++ Sbjct: 646 DKDKENEINNLLYVINIKNKKIKEELEAFTNSFNVLKKLKMKNDEIINIYKNRENVFLTT 705 Query: 422 VDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKV 481 ++K + EK K+ +L ++ ++ ++ I N +++ E K Sbjct: 706 INK---LEEK---RKLKYAEFKEKEKQYKELIMKKEELLK----IXQINNKKNI-ETFKN 754 Query: 482 QEQLKQELNDEIK--DVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQ 539 QEQ+ L DEI+ ++ K+ IE+LK E+ ++N E K + +N + ++ + Sbjct: 755 QEQM---LKDEIQKIELKTKEKIEELKQDFEKTQKINMENLEMEKESF-INNNLENEINK 810 Query: 540 MQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVY 599 M++ ++ K KE E+ + Q E+E+ K N + +++S + + Y Sbjct: 811 MKEKLE--EKYETQIKE-----TEMKYKYQIKEEIEKTKQNAE---QNFNS----KFEKY 856 Query: 600 KKMIEMEN---LAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVC 656 K+ +E + ++ + +ES K D+ Q+ +K+ E +KL LQ++ Sbjct: 857 KENLEKNKNDFINNLIIEKNNEIESFKNDIEQKKFKEMEKFKEENEKL-----LQNN--F 909 Query: 657 SEIKSVHLEEQIDALSASKKELALVIEN-LKLDKEQL-YGTIKDLENDKEDIMNKLQNYI 714 +K+ +EEQ + KKE L+ N ++ KE++ I+++EN + + ++ +I Sbjct: 910 ENMKNHFIEEQNKHIENIKKEYELIKNNEIEYLKEEMKKNKIQEIENVELKLADEKNKHI 969 Query: 715 QENMDLTDKLEKMSAEKISELLAKINHEE---QSKIQTQFGIDAKIQERDLYIENIESEL 771 D+ +LE + +I+ L KIN E+ Q ++TQ R+ Y + +E + Sbjct: 970 D---DMKKELENIYNVEINNLKEKINAEQTLAQEMLETQ---------RNEYEQKLEIQR 1017 Query: 772 SKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLM 831 ++Y+ +LE ME++ +++ LGS K SE I D+ + +L + + Sbjct: 1018 NEYEQ---QLEIRRNEMENKLIEQRKESYDLGS------KKESEIQILTDK-IEKLKMEI 1067 Query: 832 DHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAES 891 + ++ K+ +++EH L + + +L +N+NL+ +L + + YN + ++ Sbjct: 1068 E---IINKEKIDLEHNISILNDERENILNQNKNLEDNLKNNEDIYN------KKINILND 1118 Query: 892 ESTKYQTQLRDLESN-LKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKY 950 E K + ++ ++ N K + ++EI+ ++ E ++ I+ +NE+Y Sbjct: 1119 EKLKLEKEIEHIKENGAKESDQIREQFADLLQEEIDRIKKESKEKVNIYIQQYNEINEEY 1178 Query: 951 -EKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMN--LELIDKHVQ-----KQQTQSPD 1002 EK EY LE K E N++++N+ +++++ + K Q + D Sbjct: 1179 EEKKKEYNDLLEKANVSNKQLTEKCEENIQKINEYEDMIKMLENQTEVLVTKKIQELNED 1238 Query: 1003 YTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEE 1062 + ++ N+ N LLK E I N+ I ++ + E K++Q + E + Sbjct: 1239 FLKKKEAFDNEKNDLLKNY-EHAITENKHIKEQLENF---TNSNEEKISQIKNQYETQIK 1294 Query: 1063 EMQRVSKQLLD--SKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEP 1120 EMQ +LL+ ++NE L+ +V+EQ+D+ + ++ + K E + ++ I Sbjct: 1295 EMQIHFDELLNETKNKNNEMLEDIVKEQNDKEQSIQHMNSVNTELVTKNEQLNLN--ITE 1352 Query: 1121 MSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLN--TELQ-ECYTKIIQ 1177 + ++ +N LK +E+ +F+ + L+ + L TE + E K + Sbjct: 1353 IKNELSNFQEKYDKLVKENNHLKNEEQTKFLDKILDLENVNKHLMEVTEKEREINIKNVN 1412 Query: 1178 -LETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLL--STVAELRSSISSAVDQRGFE 1234 +++L ++ + +E ++LK ++ QL + N + + + SSI++A+ + + Sbjct: 1413 IIKSLQNQINEQTKLYKEYTDELKDEILQLKKQKKNSIDSNVPIDANSSINNALIEENKK 1472 Query: 1235 IAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQ 1270 + +L + ++ + L +LS ESK ++ Sbjct: 1473 L-KLQNEVISTKNDTMSTVLDNLTKRLSFIESKIKE 1507 Score = 109 bits (263), Expect = 5e-22 Identities = 202/1037 (19%), Positives = 453/1037 (43%), Gaps = 83/1037 (8%) Query: 315 SLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPL-ISRK 373 S EI +K+E +E + + E + M ++ V+S S +S + Sbjct: 477 SNEIPEKGGKMEKVEKMEKMEKMEKMEKVEKMEEFEKMEKSNEHVNSFSMFNLDKGVSVE 536 Query: 374 SGRNTASKMKSPWSQLSSETLNQDT-----DKKINKNEIAKLEMVIQSLNKDLVDKEYVI 428 S N + ++P S T+N++ K+ +N + +++ +Q NK+ +D +I Sbjct: 537 STSNIIAMDENPIILNDSNTINKNNIIDAESDKLVQNILDMIKIKLQDDNKNNIDT--II 594 Query: 429 SEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQE 488 + G ++ + ++ E + T E+ ++I + + + E Sbjct: 595 KNESKRITSLLEEKTGSMEILCNKICQLKKKNEDVEDKN-DTIREETHQI-NIDKDKENE 652 Query: 489 LND-----EIKDVNVKDLIEKLKSAEEQITQL---NDEIDAANKNMIKVKSNHKLKLKQM 540 +N+ IK+ +K+ +E ++ + +L NDEI KN V KL++ Sbjct: 653 INNLLYVINIKNKKIKEELEAFTNSFNVLKKLKMKNDEIINIYKNRENVFLTTINKLEEK 712 Query: 541 QKT-IDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVY 599 +K F + KE++ EEL + Q + E Q ++ D + IE Sbjct: 713 RKLKYAEFKEKEKQYKELIMKKEELLKIXQINNKKNIETFKNQEQMLK-DEIQKIELKTK 771 Query: 600 KKMIEM-ENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSE 658 +K+ E+ ++ +T+ + LE +K + + L+ + +++++KL + + Q + + Sbjct: 772 EKIEELKQDFEKTQKINMENLEMEKESFIN--NNLENEINKMKEKLEEKYETQIKETEMK 829 Query: 659 IKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENM 718 K ++E+I+ K+ A N K +K + ++LE +K D +N L I++N Sbjct: 830 YK-YQIKEEIE----KTKQNAEQNFNSKFEKYK-----ENLEKNKNDFINNL--IIEKNN 877 Query: 719 DLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAK--IQERDLYIENIESELSKYKS 776 ++ + +K E+ K E + +Q F I+E++ +IENI+ E K+ Sbjct: 878 EIESFKNDIEQKKFKEM-EKFKEENEKLLQNNFENMKNHFIEEQNKHIENIKKEYELIKN 936 Query: 777 R-ICRLEESIAVMEDRRY-SLERK-ADQLGSYLQEKQKAYSE-YTIQEDELVNRLAVLMD 832 I L+E + + + ++E K AD+ ++ + +K Y ++ +N L ++ Sbjct: 937 NEIEYLKEEMKKNKIQEIENVELKLADEKNKHIDDMKKELENIYNVE----INNLKEKIN 992 Query: 833 HDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRT-DLAES 891 ++ + +++LE + E QK E Q L+I ++M+ N L+E+ + DL Sbjct: 993 AEQTLAQEMLETQRNEYE-QKLEIQRNEYEQQLEIRRNEME---NKLIEQRKESYDLG-- 1046 Query: 892 ESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEK-- 949 +K +++++ L ++++ E + +I ++K ++E N + E+ + K L + Sbjct: 1047 --SKKESEIQILTDKIEKLKMEIE-IINKEKIDLEHNISILNDERENILNQNKNLEDNLK 1103 Query: 950 -----YEKNIEYVTQLEAQLQEYKNNI-ENLNMNVEELNKMNLELIDKHVQKQQTQSPDY 1003 Y K I + + +L++ +I EN +++ + +L+ + + + + +S + Sbjct: 1104 NNEDIYNKKINILNDEKLKLEKEIEHIKENGAKESDQIREQFADLLQEEIDRIKKESKEK 1163 Query: 1004 TEQYINEINKLNALLKQKDEEIIALNQKIN--NAQVSY-----MSMVSDYESKLAQFTTK 1056 YI + N++N ++K +E L +K N N Q++ + +++YE + + Sbjct: 1164 VNIYIQQYNEINEEYEEKKKEYNDLLEKANVSNKQLTEKCEENIQKINEYEDMIKMLENQ 1223 Query: 1057 LENM-EEEMQRVSKQLLDSKQ-HNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMII 1114 E + +++Q +++ L K+ + E L++ + I E K K E N + I Sbjct: 1224 TEVLVTKKIQELNEDFLKKKEAFDNEKNDLLKNYEHAITENKHIKEQLE-NFTNSNEEKI 1282 Query: 1115 SSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTK 1174 S + + E+ ++E++ ++ +N+ E TK Sbjct: 1283 SQIKNQYETQIKEMQIHFDELLNETKNKNNEMLEDIVKEQNDKEQSIQHMNSVNTELVTK 1342 Query: 1175 IIQLETLNTELTGHDVVNQEQINQLKSKLEQL-NTENDNLLSTVAELRSSISSAVDQRGF 1233 QL TE+ QE+ ++L + L N E L + +L + V++ Sbjct: 1343 NEQLNLNITEIKNELSNFQEKYDKLVKENNHLKNEEQTKFLDKILDLEN-----VNKHLM 1397 Query: 1234 EIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKI---VTME 1290 E+ E ++ + + ++++ Q ++ ++L D + +++ N I V ++ Sbjct: 1398 EVTEKEREINIKNVNIIKSLQNQINEQTKLYKEYTDELKDEILQLKKQKKNSIDSNVPID 1457 Query: 1291 QVTSLQNKLQDKEEHLR 1307 +S+ N L ++ + L+ Sbjct: 1458 ANSSINNALIEENKKLK 1474 Score = 99.1 bits (236), Expect = 9e-19 Identities = 180/890 (20%), Positives = 395/890 (44%), Gaps = 82/890 (9%) Query: 461 EGPSLIHVGTNTEDVNEIAKVQ-EQLKQELNDEIK----DVNVKDLIEKLKSAEEQITQL 515 E P +++ +NT + N I + ++L Q + D IK D N ++ +K+ ++IT L Sbjct: 546 ENPIILN-DSNTINKNNIIDAESDKLVQNILDMIKIKLQDDNKNNIDTIIKNESKRITSL 604 Query: 516 NDEIDAANKNMIKVKSNHKLKLKQMQKTI-DNFSKVSDSNKEIVRLTEELHHLSQKVAEL 574 +E +++ N +LK+ + + D + + +I ++ + ++ + + Sbjct: 605 LEE----KTGSMEILCNKICQLKKKNEDVEDKNDTIREETHQINIDKDKENEINNLLYVI 660 Query: 575 EEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETR----LKAISLLESQKFDLVQEL 630 + ++ L + + + + K E+ N+ + R L I+ LE ++ E Sbjct: 661 NIKNKKIKEELEAFTNSFNVLKKLKMKNDEIINIYKNRENVFLTTINKLEEKRKLKYAEF 720 Query: 631 HILQQKYDEV---EDKLADISQLQSDQVCSEIKSVH--LEEQIDALSASKKELALVIENL 685 +++Y E+ +++L I Q+ + + K+ L+++I + KE IE L Sbjct: 721 KEKEKQYKELIMKKEELLKIXQINNKKNIETFKNQEQMLKDEIQKIELKTKEK---IEEL 777 Query: 686 KLDKEQLYG-TIKDLENDKED-IMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEE 743 K D E+ +++LE +KE I N L+N I + + +KLE+ +I E K ++ Sbjct: 778 KQDFEKTQKINMENLEMEKESFINNNLENEINK---MKEKLEEKYETQIKETEMKYKYQI 834 Query: 744 QSKIQ-TQFGIDAKIQER-DLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQ 801 + +I+ T+ + + + Y EN+E + + + + +E++ + + ++K + Sbjct: 835 KEEIEKTKQNAEQNFNSKFEKYKENLEKNKNDFINNLI-IEKNNEIESFKNDIEQKKFKE 893 Query: 802 LGSYLQEKQKAY-SEYTIQEDELVNRLAVLMDHDRVVEKQLL---EIEHENKELQKKNQI 857 + + +E +K + + ++ + +++ + E +L+ EIE+ +E+ KKN+I Sbjct: 894 MEKFKEENEKLLQNNFENMKNHFIEEQNKHIENIKK-EYELIKNNEIEYLKEEM-KKNKI 951 Query: 858 LLEENQNLQISLSDMQ-QHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQT 916 +E +N+++ L+D + +H + + ++ E + K + + E L + E Q Sbjct: 952 --QEIENVELKLADEKNKHIDDMKKELENIYNVEINNLKEKI---NAEQTLAQEMLETQR 1006 Query: 917 LIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNM 976 ++K EI+ E E +I + K++ ++ E + + ++ E+++Q + IE L M Sbjct: 1007 NEYEQKLEIQRNEYEQQLEIRRNEMENKLIEQRKE-SYDLGSKKESEIQILTDKIEKLKM 1065 Query: 977 NVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQ 1036 +E +NK ++L + + D E +N+ L LK ++ N+KIN Sbjct: 1066 EIEIINKEKIDL-----EHNISILNDERENILNQNKNLEDNLKNNED---IYNKKIN--- 1114 Query: 1037 VSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELK 1096 +++D + KL + ++E+++E + S Q+ E+ L++E+ D+IK K Sbjct: 1115 -----ILNDEKLKLEK---EIEHIKENGAKESDQI------REQFADLLQEEIDRIK--K 1158 Query: 1097 ETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSV 1156 E+K ++NI + I+ E + N++ ++ EE IQ+ + Sbjct: 1159 ESKE--KVNIYIQQYNEINEEYEEKKKEYNDL----LEKANVSNKQLTEKCEENIQKINE 1212 Query: 1157 LQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLST 1216 ++ L + + TK IQ LN + + N L E TEN ++ Sbjct: 1213 YEDMIKMLENQTEVLVTKKIQ--ELNEDFLKKKEAFDNEKNDLLKNYEHAITENKHIKEQ 1270 Query: 1217 VAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQ 1276 + +S + Q + K+ + +T+++ L + S+Q Sbjct: 1271 LENFTNSNEEKISQIKNQYETQIKEMQIHFDELLNETKNKNNEMLEDIVKEQNDKEQSIQ 1330 Query: 1277 SSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSE 1326 T + EQ L + + + L N QEKY ++ + L++E Sbjct: 1331 HMNSVNTELVTKNEQ---LNLNITEIKNELSNFQEKYDKLVKENNHLKNE 1377 Score = 70.9 bits (166), Expect = 3e-10 Identities = 130/651 (19%), Positives = 271/651 (41%), Gaps = 50/651 (7%) Query: 919 VQKKKEIEDLEIEFNTQIESAIR---DKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLN 975 V+K +E E +E + N + S DK V E NI + + L + N I N Sbjct: 505 VEKMEEFEKME-KSNEHVNSFSMFNLDKGVSVES-TSNIIAMDENPIILND-SNTINKNN 561 Query: 976 MNVEELNKMNLELIDKHVQKQQTQSPDYTEQYI-NEINKLNALLKQKDEEIIALNQKINN 1034 + E +K+ ++D K Q + + + I NE ++ +LL++K + L KI Sbjct: 562 IIDAESDKLVQNILDMIKIKLQDDNKNNIDTIIKNESKRITSLLEEKTGSMEILCNKICQ 621 Query: 1035 AQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKE 1094 + V D + + T ++ +++ ++ L N++++ + + Sbjct: 622 LKKKNED-VEDKNDTIREETHQINIDKDKENEINNLLYVINIKNKKIKEELEAFTNSFNV 680 Query: 1095 LKETKLTFE--MNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQ 1152 LK+ K+ + +NI K + +TI + ++ + + ++EE ++ Sbjct: 681 LKKLKMKNDEIINIYKNRENVFLTTINKL-EEKRKLKYAEFKEKEKQYKELIMKKEELLK 739 Query: 1153 ERSVLQEQSAKLNTELQECYTKIIQLETLNT----ELTGHDVVNQEQINQLKSKLEQLNT 1208 + +++ + ++ IQ L T E D ++IN ++E+ + Sbjct: 740 IXQINNKKNIETFKNQEQMLKDEIQKIELKTKEKIEELKQDFEKTQKINMENLEMEKESF 799 Query: 1209 ENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKY 1268 N+NL + + +++ + + +I E ++ Q + + +KT+ F SK+ Sbjct: 800 INNNLENEINKMKEKLEEKYET---QIKETEMKYKYQIKEEIEKTKQNAEQN---FNSKF 853 Query: 1269 EQLLDSVQSSTQEETNKIVTME--QVTSLQNKLQDKE-EHLRNLQEKYADVI-NQIEILR 1324 E+ ++++ + + N ++ + ++ S +N ++ K+ + + +E+ ++ N E ++ Sbjct: 854 EKYKENLEKNKNDFINNLIIEKNNEIESFKNDIEQKKFKEMEKFKEENEKLLQNNFENMK 913 Query: 1325 SEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXX 1384 + +E+ + E ++QE + + + + K Sbjct: 914 NHFIEEQNKHIENIKKEYELIKNNEIEYLKEEMKKNKIQEIENVELKLADEKNKHIDDMK 973 Query: 1385 XXXXXXXXXRVNDAEAKV-LELT---HQLELKDSEIYQKT----HEYTITLTQRNDEFEN 1436 +N+ + K+ E T LE + +E QK +EY L R +E EN Sbjct: 974 KELENIYNVEINNLKEKINAEQTLAQEMLETQRNEYEQKLEIQRNEYEQQLEIRRNEMEN 1033 Query: 1437 VRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKIT 1496 +L+E K DL +KESE+ IL K+ + E + KE K+ E N+ I Sbjct: 1034 ---KLIEQRKESYDLGSKKESEIQILTDKIEKLKMEIEIINKE------KIDLEHNISIL 1084 Query: 1497 ESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMV 1547 N + NK LE+ + K NE + N++I I LNDE L+ + Sbjct: 1085 NDEREN--ILNQNKNLEDNL-KNNE---DIYNKKINI--LNDEKLKLEKEI 1127 Score = 64.5 bits (150), Expect = 2e-08 Identities = 161/811 (19%), Positives = 334/811 (41%), Gaps = 97/811 (11%) Query: 831 MDHDRVVEK--QLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALV----EKAN 884 M+ VEK + ++E N+ + + L++ +++ + + + N ++ N Sbjct: 499 MEKMEKVEKMEEFEKMEKSNEHVNSFSMFNLDKGVSVESTSNIIAMDENPIILNDSNTIN 558 Query: 885 RTDLAESESTKYQTQLRDLESNLKRITHEHQ--TLIVQKKKEIEDLEIEFNTQIESAIRD 942 + ++ ++ES K + D+ + +++ T+I + K I L E +E I Sbjct: 559 KNNIIDAESDKLVQNILDMIKIKLQDDNKNNIDTIIKNESKRITSLLEEKTGSME--ILC 616 Query: 943 KKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPD 1002 K+ K +KN + +E + + +N++ ++ N++N L +++ ++ + + Sbjct: 617 NKICQLK-KKNED----VEDKNDTIREETHQINIDKDKENEINNLLYVINIKNKKIK--E 669 Query: 1003 YTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYES-KLAQFTTKLENME 1061 E + N N L L K K++EII + + N ++ ++ + + K A+F K E Sbjct: 670 ELEAFTNSFNVLKKL-KMKNDEIINIYKNRENVFLTTINKLEEKRKLKYAEFKEK-EKQY 727 Query: 1062 EEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPM 1121 +E+ ++LL Q N + I + +Q+ LK+ E+ + + + Sbjct: 728 KELIMKKEELLKIXQINNKKNIETFKNQEQM--LKDEIQKIELKTKEKIEELKQDFEKTQ 785 Query: 1122 SDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETL 1181 + N++ ++ + +E ++E+ Q + ++ + Q I+ E Sbjct: 786 KINMENLEMEKESFINNNLENEINKMKEKLEEKYETQIKETEMKYKYQ------IKEEIE 839 Query: 1182 NTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSA---VDQRGFEIAEL 1238 T+ N + + K LE+ +ND + + + E + I S ++Q+ F+ E Sbjct: 840 KTKQNAEQNFNSK-FEKYKENLEK--NKNDFINNLIIEKNNEIESFKNDIEQKKFKEMEK 896 Query: 1239 WKQH---LAQREADFQKTE--HELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVT 1293 +K+ L Q + K E + + +YE + ++ +EE K ++++ Sbjct: 897 FKEENEKLLQNNFENMKNHFIEEQNKHIENIKKEYELIKNNEIEYLKEEMKKN-KIQEIE 955 Query: 1294 SLQNKLQD-KEEHLRNLQEKYADVIN-QIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXD 1351 +++ KL D K +H+ +++++ ++ N +I L+ +I E+ Sbjct: 956 NVELKLADEKNKHIDDMKKELENIYNVEINNLKEKINAEQTL---AQEMLETQRNEYEQK 1012 Query: 1352 LRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLEL 1411 L + Y+Q E + NE +L + + K+ +L ++E+ Sbjct: 1013 LEIQRNEYEQQLE---IRRNEMENKLIEQRKESYDLGSKKESEIQILTDKIEKLKMEIEI 1069 Query: 1412 KDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYE---KRIEDLTYEKESELAILRLKMHE 1468 + E H +I NDE EN+ Q E K ED+ +K + L +LK+ + Sbjct: 1070 INKEKIDLEHNISIL----NDERENILNQNKNLEDNLKNNEDIYNKKINILNDEKLKLEK 1125 Query: 1469 NANHY-ETMQKES-------------EIERVKLI--EELNVKITESVSLNKQVAEL---- 1508 H E KES EI+R+K E++N+ I + +N++ E Sbjct: 1126 EIEHIKENGAKESDQIREQFADLLQEEIDRIKKESKEKVNIYIQQYNEINEEYEEKKKEY 1185 Query: 1509 ----------NKAL----EEEVAKTNE---MQTALENQEIEIVT-----LNDEITNLQNM 1546 NK L EE + K NE M LENQ +VT LN++ + Sbjct: 1186 NDLLEKANVSNKQLTEKCEENIQKINEYEDMIKMLENQTEVLVTKKIQELNEDFLKKKEA 1245 Query: 1547 VRASSSKIQKHVSFASDTKQGRDEQLDNTMN 1577 + + K+ A + EQL+N N Sbjct: 1246 FDNEKNDLLKNYEHAITENKHIKEQLENFTN 1276 Score = 59.3 bits (137), Expect = 9e-07 Identities = 145/782 (18%), Positives = 307/782 (39%), Gaps = 58/782 (7%) Query: 845 EHENKELQKKNQILLEENQN-LQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDL 903 E L K + +L+ N+N + + + + K N +L E KY ++ D Sbjct: 205 EEFTNNLNKISDNVLDGNKNNIPFESNHINDKERTSLSKDNLFNLNEINKNKYDSKNDDN 264 Query: 904 ESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIE-SAIRDKKVLNEK-YEKNIEYV---T 958 +NL + E+QTLI K E+ ++E E + + + ++ K NI Sbjct: 265 NNNL--LFSENQTLIPAKVNEVTEIEASRTPNYEINRVPNYEINKSKGIHPNIPQFNNPA 322 Query: 959 QLEAQLQEYKNNI--ENLNMNVEELNKM-NLELIDKHVQKQQTQSPDYTEQYINEINKLN 1015 QL ++ KNNI +N++ + + NLE +K +++ + ++ N INK N Sbjct: 323 QLPTEI-NIKNNINYDNISPKINSKGVIENLENKNKEIKRISMDNFEFNNPISNHINKRN 381 Query: 1016 ALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENM--EEEMQRVSKQLLD 1073 + + + + N Q+ Y ++ ++ K N+ E ++ +S ++++ Sbjct: 382 S---------TTVVRSVFNPQLEYNNVENNEIRKFNTIGNNYMNIGRENDILNISPKVIE 432 Query: 1074 SKQHNEELQILVREQDDQIKELKETKLTFEM---NIPKTEGMIISSTIEPMSDDANNVDX 1130 Q+ + +L K+T NI +S+ I V+ Sbjct: 433 KINRRNTHQLFNESSNISTDKLTIHKVTSPFLFDNINNDSNTNVSNEIPEKGGKMEKVEK 492 Query: 1131 XXXXXXXXXXXLKVQEEEEFIQ-ERSVLQEQS-AKLNTE---LQECYTKIIQLETLNTEL 1185 KV++ EEF + E+S S + N + E + II ++ L Sbjct: 493 MEKMEKMEKME-KVEKMEEFEKMEKSNEHVNSFSMFNLDKGVSVESTSNIIAMDENPIIL 551 Query: 1186 TGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQ 1245 + +N+ I +S N + + + +++I + + I L ++ Sbjct: 552 NDSNTINKNNIIDAESDKLVQNILDMIKIKLQDDNKNNIDTIIKNESKRITSLLEEKTGS 611 Query: 1246 READFQKTEHELRVQLSAFESKYEQLLDSVQ--SSTQEETNKIVTMEQVTSLQNKLQDKE 1303 E K +L+ + E K + + + + +++ N+I + V +++NK + KE Sbjct: 612 MEILCNKI-CQLKKKNEDVEDKNDTIREETHQINIDKDKENEINNLLYVINIKNK-KIKE 669 Query: 1304 EHLRNLQEKYADVINQIEILRSEI----EDEKVAFXXXXXXXXXXXXXXXXDLRTENQSY 1359 E L + +V+ ++++ EI ++ + F + + + + Y Sbjct: 670 E-LEAFTNSF-NVLKKLKMKNDEIINIYKNRENVFLTTINKLEEKRKLKYAEFKEKEKQY 727 Query: 1360 KQ--MQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIY 1417 K+ M+++ +L I + N KK+ + E K E +L+ +D E Sbjct: 728 KELIMKKEELLKIXQINN--KKNIETFKNQEQMLKDEIQKIELKTKEKIEELK-QDFEKT 784 Query: 1418 QKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQ 1477 QK + + + + + N+ ++ + ++++E+ YE + + ++ K +T Q Sbjct: 785 QKINMENLEMEKESFINNNLENEINKMKEKLEE-KYETQIKETEMKYKYQIKEEIEKTKQ 843 Query: 1478 KESEIERVKLIE-ELNVKITESVSLNKQVAELNKALEE-----EVAKTNEMQTALENQEI 1531 + K + + N++ ++ +N + E N +E E K EM+ E E Sbjct: 844 NAEQNFNSKFEKYKENLEKNKNDFINNLIIEKNNEIESFKNDIEQKKFKEMEKFKEENE- 902 Query: 1532 EIVTLNDEITNLQN-MVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELD 1590 L + N++N + + I+ K E L M K + + EL Sbjct: 903 --KLLQNNFENMKNHFIEEQNKHIENIKKEYELIKNNEIEYLKEEMKKNKIQEIENVELK 960 Query: 1591 LA 1592 LA Sbjct: 961 LA 962 >UniRef50_UPI00006A154D Cluster: Centrosomal protein 2 (Centrosomal Nek2-associated protein 1) (C-NAP1) (Centrosome protein 250) (Centrosome-associated protein CEP250).; n=1; Xenopus tropicalis|Rep: Centrosomal protein 2 (Centrosomal Nek2-associated protein 1) (C-NAP1) (Centrosome protein 250) (Centrosome-associated protein CEP250). - Xenopus tropicalis Length = 1575 Score = 129 bits (311), Expect = 7e-28 Identities = 280/1436 (19%), Positives = 591/1436 (41%), Gaps = 137/1436 (9%) Query: 216 QQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLA 275 Q++ ++QE+ + + L +I + + E A + LEA ++ E +L Sbjct: 173 QRIERLQESEKELALAREQLHSELSAEIAKRQHQAQESEGAKESLEAELADVMGERERLQ 232 Query: 276 QEL---EQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLE 332 EL Q L KQ + + ++E+ EI ++ E ++ + Sbjct: 233 AELTQDSQTEKETALYNLEHQTLMKQELSRETQLNLTVQER-EREIRSLKENIQRAQQEN 291 Query: 333 HLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRK-SGRNTASKMKSPWSQLSS 391 QIR+ K+ E M E + + S+KG + K S + KM++ ++ S Sbjct: 292 EAAEQIRECEKDRE---TAMKAEESSRITLSEKGREISKMKESEKEHQFKMENALKEIES 348 Query: 392 ETL---NQDTDKKINKNEIAKLEMVIQSLNKDLVDKE-YVISEKDTXXXXXXXXXXGKDT 447 +T+ +DT + K + + E I +N+ K ++ E++ + Sbjct: 349 QTIILREKDTFLETLKQRLKECEEEI--MNELQRQKHMLIVEERERDIKILQESVQREKD 406 Query: 448 LIAQL------QLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDL 501 ++ + Q E + + +LI E+ K+ ++ Q D +K ++ Sbjct: 407 MVKHISDQWESQRESSERQKESTLIQHRLIVEERERDIKILQESVQRERDMVKHIS-DQW 465 Query: 502 IEKLKSAEEQ----ITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSD----S 553 + +SAE Q I++L+ + + ++ K +Q+ +D+ ++ + + Sbjct: 466 ESQRESAERQKENKISELSQALSKKEREAELLERQTKRDSDLLQEQLDSLTQHLEEKEIA 525 Query: 554 NKEIVRLTEELHHLSQKVAEL---EEEKGN----LQLHLVDYDSGRMIESDVYKKMIEME 606 +K+ L E L QKV+EL EE + LQ L + S + E+++ + I+ Sbjct: 526 HKKNSELQRENMALEQKVSELTQAEEHREKDIKFLQERLKEL-SQTLTENEIGTERIKQH 584 Query: 607 NLAET-RLK--------AISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCS 657 +T LK A+++ ++++ + ++++ L+++ + E L+D + D+ Sbjct: 585 AEKDTSALKVRVSELSAALTMRDTKELETLEQIKSLKREIESCEMALSDKEKRAEDERRQ 644 Query: 658 EIKSV-HLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNK--LQNYI 714 K + + +++ LS + + E +++ L G +++LE+ E+ K ++ I Sbjct: 645 SEKEISSVRQRVTELSEAIMSKEIQQEEREIEVRALKGRLEELEHALEESAEKSRVERQI 704 Query: 715 QENMDLTDKLEKM-SAEKISELLAKINHEEQSKIQ---TQFGIDAKIQERDLYIENIESE 770 +E L + E A K E +H E+ ++ + D +ERD E E Sbjct: 705 REGDTLIQRAELFGKALKEKERRHMDDHREKEMLRQRVNELSQDIINKERD-----AEEE 759 Query: 771 LSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVL 830 L + + L +++ E+ + +R+++ L+ K + ++E+ + V Sbjct: 760 LKALRRKTVELRQTLIEKEEDKAEEQRRSENEKEALRHKATGLLQ-ALEEERMA--AEVR 816 Query: 831 MDHDRVVEKQLLEIEHENKELQKKNQILLE---ENQNLQISLSDMQQHYNAL-------- 879 + + LLE E E ++ +K+ Q L + E + LQ ++ +++ L Sbjct: 817 QGRLEITSQALLEKEIETEKQEKERQTLDKKDREGETLQEEMAAVRRKREELGQALRDKE 876 Query: 880 VEKANRTDLAESESTKYQTQLRDLESNLKR------ITHEHQTLIVQKKKEI-EDLEIEF 932 EK E E+ +++DL L I E T + +K +E+ + L+ + Sbjct: 877 QEKCEADTQKEKENESLSKKVKDLSQALLEKEREADILQEEVTAVRRKGEELKQTLKDKE 936 Query: 933 NTQIESAIRDKK---VLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELI 989 +IE ++++K L+ K E + + + E + + + + EEL + + Sbjct: 937 QDKIEKEVQNEKEREALSLKVEHLSQALLEKEREADTLQEEVTAVRRKGEELKQTLKDKE 996 Query: 990 DKHVQKQQTQSPDYTEQYINEINKLNALLKQKD-------EEIIALNQKINNAQVSYMSM 1042 K ++K + Q+ E ++ +L+ L +K+ EE+ AL +K + + + Sbjct: 997 QKKIEK-EVQNDKEKEALSQKVKQLSQALLEKEREADTLQEEVAALRRKGEELKQTLKNK 1055 Query: 1043 VSDYESKLAQFTTKLENMEEEMQRVSKQLLD-------SKQHNEELQILVRE----QDDQ 1091 ++ K Q + E ++++ +S+ LL+ +K E+L I +R+ Q + Sbjct: 1056 EQEHIEKEVQNEKEKEAQSQKVEHLSQALLEKESEVELTKGKKEDLTIQIRDLRQFQLEN 1115 Query: 1092 IKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFI 1151 KE+KE + + + + +I+ T++ ++ ++ LKV+E EE Sbjct: 1116 EKEIKEEERQSRLKVTELSETLINKTLQ---EEEKQLE--VKSLKGKTLKLKVKECEEEK 1170 Query: 1152 QERSVLQEQSAKLNTELQECYTKIIQLE-TLNT--ELTGHDVVNQEQINQLKSKLEQLNT 1208 +ER L ++ ++L+ L E +E +NT E G + Q K++ Q Sbjct: 1171 KERKKLNQKVSELSQALLEKQRNSEMIEQEMNTLREKIGESGKALIEKEQEKAEARQSVK 1230 Query: 1209 ENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKY 1268 E + L VAEL ++ QR E+ E L ++ + K + E + Sbjct: 1231 EKETLRQKVAELSQALLE--KQRNSEMIEQEMNSLREKIGETGK---------AFIEKEQ 1279 Query: 1269 EQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQI-----EIL 1323 E+ + QS + ET + E +L K +D + L +L+EK ++ + EI Sbjct: 1280 EKAEEGRQSVKESETLRQKVAELSQALLQKERDVGQELVSLREKIGELAQTLVKKEKEIK 1339 Query: 1324 RSEIEDEKVAFXXXXXXXXXXXXXXXXDLR-TENQSYKQ-MQEQSILNINEENAQLKKSS 1381 E E E+V +L TE ++ ++ + E ++ IN+E +L + Sbjct: 1340 EGEQEKEEVKLKLTSLCQSLKEKETEVELTGTELKATREKVGELRLVLINKER-ELNEEK 1398 Query: 1382 XXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQL 1441 RV ++E L K+ E+ + + I + ++ + Sbjct: 1399 RQSECEKEELKQRVESLSQALVEKDRALIEKEEEVKEGAKQSKIEVEALRNQLVQLELAQ 1458 Query: 1442 VEYEKRIEDLTYEKE--------SELAILRLKMHENANHYETMQKESEIERVKLIEELNV 1493 + + DL EK+ SE R+ + E K E++++K EE +V Sbjct: 1459 AQEMQEKGDLQDEKDRQAKEQQISESEKERMALGERIIEISRDLKRREVKQIK-EEEESV 1517 Query: 1494 KITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRA 1549 + + +L K+ E + E + + AL + E E + ++ L++ RA Sbjct: 1518 SLQKIETLQKENKEGKQREERLKHRLRRTEMALRHTESEEIAWREKARELESKYRA 1573 Score = 105 bits (252), Expect = 1e-20 Identities = 201/1097 (18%), Positives = 455/1097 (41%), Gaps = 80/1097 (7%) Query: 536 KLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIE 595 +L+ M+ ++ +V S + V E+ + +LE K + Q + + E Sbjct: 34 ELRSMRSQVETADEVERSLRSQVATLEQ--DIRSTRLQLETSKEDTQ-SMTSRLEAQKEE 90 Query: 596 SDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQV 655 + + + +E E ET + E + L Q++ + + + V +LA S L+++ + Sbjct: 91 AAILRSQLEAEE--ETSQLKLKASEQEIKALRQQIQMSEAELSFVRSELAG-STLEAESL 147 Query: 656 CSEIKSVHLE---------------EQIDALSASKKELALVIENL--KLDKE--QLYGTI 696 S +++ +E ++I+ L S+KELAL E L +L E + Sbjct: 148 KSRLETYEMEAKSRLEDKKQELRISQRIERLQESEKELALAREQLHSELSAEIAKRQHQA 207 Query: 697 KDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEE--QSKIQTQFGID 754 ++ E KE + +L + + E L +L + S + L + H+ + ++ + ++ Sbjct: 208 QESEGAKESLEAELADVMGERERLQAELTQDSQTEKETALYNLEHQTLMKQELSRETQLN 267 Query: 755 AKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSY-LQEKQKAY 813 +QER+ I +++ + + + E+ +DR ++ KA++ L EK + Sbjct: 268 LTVQEREREIRSLKENIQRAQQENEAAEQIRECEKDRETAM--KAEESSRITLSEKGREI 325 Query: 814 SEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQ 873 S+ E E ++ + + +E Q + + ++ L+ Q L E + + L + Sbjct: 326 SKMKESEKEHQFKMENAL---KEIESQTIILREKDTFLETLKQRLKECEEEIMNEL--QR 380 Query: 874 QHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFN 933 Q + +VE+ R ES + + + +K I+ + ++ +++ E I+ Sbjct: 381 QKHMLIVEERERDIKILQESVQREKDM------VKHISDQWESQRESSERQKESTLIQHR 434 Query: 934 TQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMN-VEELNKMNLELIDKH 992 +E RD K+L E ++ + V + Q + + + E N + EL++ L ++ Sbjct: 435 LIVEERERDIKILQESVQRERDMVKHISDQWESQRESAERQKENKISELSQA-LSKKERE 493 Query: 993 VQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQ 1052 + + Q+ ++ +++ L L++K E N ++ ++ VS+ Sbjct: 494 AELLERQTKRDSDLLQEQLDSLTQHLEEK-EIAHKKNSELQRENMALEQKVSELTQAEEH 552 Query: 1053 FTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGM 1112 ++ ++E ++ +S+ L +++ E ++ E+D +++ ++L+ + + T+ + Sbjct: 553 REKDIKFLQERLKELSQTLTENEIGTERIK-QHAEKDTSALKVRVSELSAALTMRDTKEL 611 Query: 1113 IISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQS-AKLNTELQEC 1171 I+ + + + + + Q E+E R + E S A ++ E+Q+ Sbjct: 612 ETLEQIKSLKREIESCEMALSDKEKRAEDERRQSEKEISSVRQRVTELSEAIMSKEIQQ- 670 Query: 1172 YTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQR 1231 + I++ L L + +E KS++E+ E D L+ AEL ++R Sbjct: 671 EEREIEVRALKGRLEELEHALEESAE--KSRVERQIREGDTLIQR-AELFGKALKEKERR 727 Query: 1232 GFE---IAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLL--------DSVQSSTQ 1280 + E+ +Q + + D E + +L A K +L D + + Sbjct: 728 HMDDHREKEMLRQRVNELSQDIINKERDAEEELKALRRKTVELRQTLIEKEEDKAEEQRR 787 Query: 1281 EETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXX 1340 E K + T L L++ E +++ ++ +Q +L EIE EK Sbjct: 788 SENEKEALRHKATGLLQALEE-ERMAAEVRQGRLEITSQ-ALLEKEIETEK---QEKERQ 842 Query: 1341 XXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEA 1400 L+ E + ++ +E+ + ++ + ++ +V D Sbjct: 843 TLDKKDREGETLQEEMAAVRRKREELGQALRDKEQEKCEADTQKEKENESLSKKVKDLSQ 902 Query: 1401 KVLELTHQLELKDSEIYQ-KTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESEL 1459 +LE + ++ E+ + + T ++ E + + ++ V+ EK E L+ + E Sbjct: 903 ALLEKEREADILQEEVTAVRRKGEELKQTLKDKEQDKIEKE-VQNEKEREALSLKVEH-- 959 Query: 1460 AILRLKMHENANHYETMQKESEIERVKLIE-ELNVKITESVSLNKQVAELNKALEEEVAK 1518 L + E +T+Q+E R K E + +K E + K+V + +K E K Sbjct: 960 --LSQALLEKEREADTLQEEVTAVRRKGEELKQTLKDKEQKKIEKEV-QNDKEKEALSQK 1016 Query: 1519 TNEMQTALENQEIEIVTLNDEITNL----QNMVRASSSKIQKHVSFASDTKQGRDEQLDN 1574 ++ AL +E E TL +E+ L + + + +K Q+H+ ++ ++ Q Sbjct: 1017 VKQLSQALLEKEREADTLQEEVAALRRKGEELKQTLKNKEQEHIEKEVQNEKEKEAQSQK 1076 Query: 1575 T--MNKELLDAVPRAEL 1589 +++ LL+ EL Sbjct: 1077 VEHLSQALLEKESEVEL 1093 Score = 99.1 bits (236), Expect = 9e-19 Identities = 260/1273 (20%), Positives = 542/1273 (42%), Gaps = 119/1273 (9%) Query: 313 KGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISR 372 + +E A+ E + + ++ L IR T +LE + + + + ++ + L S+ Sbjct: 39 RSQVETADEVERSLRSQVAT-LEQDIRSTRLQLETSKEDTQSMTSRLEAQKEEAAILRSQ 97 Query: 373 KSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKD 432 S++K S+ + L Q +I +E A+L V L ++ E + S + Sbjct: 98 LEAEEETSQLKLKASEQEIKALRQ----QIQMSE-AELSFVRSELAGSTLEAESLKSRLE 152 Query: 433 TXXXXXXXXXXGK-DTLIAQLQLEHQQHMEGP-SLIHVGTNTEDVNEIAKVQEQLKQ-EL 489 T K L ++E Q E +L ++E EIAK Q Q ++ E Sbjct: 153 TYEMEAKSRLEDKKQELRISQRIERLQESEKELALAREQLHSELSAEIAKRQHQAQESEG 212 Query: 490 NDEIKDVNVKDLI---EKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDN 546 E + + D++ E+L++ Q +Q E N + + Q+ T+ Sbjct: 213 AKESLEAELADVMGERERLQAELTQDSQTEKETALYNLEHQTLMKQELSRETQLNLTVQE 272 Query: 547 FSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEM- 605 + S KE ++ ++ + ++++ E E+++ + + +S R+ S+ +++ +M Sbjct: 273 REREIRSLKENIQRAQQENEAAEQIRECEKDR---ETAMKAEESSRITLSEKGREISKMK 329 Query: 606 ENLAETRLK---AISLLESQKFDLVQE---LHILQQKYDEVEDKLADISQLQSDQVCSEI 659 E+ E + K A+ +ESQ L ++ L L+Q+ E E+++ + Q Q + E Sbjct: 330 ESEKEHQFKMENALKEIESQTIILREKDTFLETLKQRLKECEEEIMNELQRQKHMLIVEE 389 Query: 660 KSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMD 719 + E I L S + +++++ +Q + E KE + + I E + Sbjct: 390 R----ERDIKILQESVQREKDMVKHIS---DQWESQRESSERQKESTLIQ-HRLIVEERE 441 Query: 720 LTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRIC 779 K+ + S ++ +++ I+ + +S+ ++ A+ Q+ EN SELS+ S+ Sbjct: 442 RDIKILQESVQRERDMVKHISDQWESQRES-----AERQK-----ENKISELSQALSKKE 491 Query: 780 RLEESIAVMEDRRYS--LERKADQLGSYLQEKQKAY---SEYTIQEDELVNRLAVLMDHD 834 R E + + +R S L+ + D L +L+EK+ A+ SE + L +++ L + Sbjct: 492 R-EAELLERQTKRDSDLLQEQLDSLTQHLEEKEIAHKKNSELQRENMALEQKVSELTQAE 550 Query: 835 RVVEKQLLEIEHENKELQK---KNQILLEE-NQNLQISLSDMQQHYNALVEKANRTDLAE 890 EK + ++ KEL + +N+I E Q+ + S ++ + L D E Sbjct: 551 EHREKDIKFLQERLKELSQTLTENEIGTERIKQHAEKDTSALKVRVSELSAALTMRDTKE 610 Query: 891 SESTKYQTQL-RDLESNLKRITHEHQTLIVQKK---KEIEDLEIEFNTQIESAIRDKKVL 946 E+ + L R++ES ++ + + +++ KEI + T++ AI K++ Sbjct: 611 LETLEQIKSLKREIESCEMALSDKEKRAEDERRQSEKEISSVRQRV-TELSEAIMSKEIQ 669 Query: 947 NEKYEKNIEYVTQLEAQLQEYKNNIEN------LNMNVEELNKM--NLELIDKHV-QKQQ 997 E E+ IE V L+ +L+E ++ +E + + E + + EL K + +K++ Sbjct: 670 QE--EREIE-VRALKGRLEELEHALEESAEKSRVERQIREGDTLIQRAELFGKALKEKER 726 Query: 998 TQSPDYTE-----QYINEINKLNALLKQKD--EEIIALNQKINNAQVSYMSMVSDYESKL 1050 D+ E Q +NE+++ + + K++D EE+ AL +K V + + E Sbjct: 727 RHMDDHREKEMLRQRVNELSQ-DIINKERDAEEELKALRRKT----VELRQTLIEKEEDK 781 Query: 1051 AQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTE 1110 A+ + EN +E ++ + LL Q EE ++ + +++ + L E+ K E Sbjct: 782 AEEQRRSENEKEALRHKATGLL---QALEEERMAAEVRQGRLEITSQALLEKEIETEKQE 838 Query: 1111 GMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQE 1170 T++ + + L Q + QE+ Q K N L + Sbjct: 839 KE--RQTLDKKDREGETLQEEMAAVRRKREELG-QALRDKEQEKCEADTQKEKENESLSK 895 Query: 1171 CYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLN-TENDNLLSTVAELRSSISSAVD 1229 K+ L E + QE++ ++ K E+L T D + + + Sbjct: 896 ---KVKDLSQALLEKEREADILQEEVTAVRRKGEELKQTLKDKEQDKIEK------EVQN 946 Query: 1230 QRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTM 1289 ++ E L +HL+Q + ++ L+ +++A K E+L +++ Q++ K V Sbjct: 947 EKEREALSLKVEHLSQALLEKEREADTLQEEVTAVRRKGEELKQTLKDKEQKKIEKEVQN 1006 Query: 1290 E-QVTSLQNKLQDKEEHLRNLQEKYADVINQ-IEILRSEIEDEKVAFXXXXXXXXXXXXX 1347 + + +L K++ + L +E+ AD + + + LR + E+ K Sbjct: 1007 DKEKEALSQKVKQLSQALLE-KEREADTLQEEVAALRRKGEELKQTLKNKEQEHIEKEVQ 1065 Query: 1348 XXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVN-DAEAKVLELT 1406 + ++Q + + Q++L E +L K + + E ++ E Sbjct: 1066 NEKEKEAQSQKVEHLS-QALLE-KESEVELTKGKKEDLTIQIRDLRQFQLENEKEIKEEE 1123 Query: 1407 HQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLV-------EYEKRIEDLTYEKESEL 1459 Q LK +E+ + T+ ++ E ++++ + + E EK+ +K SEL Sbjct: 1124 RQSRLKVTELSETLINKTLQEEEKQLEVKSLKGKTLKLKVKECEEEKKERKKLNQKVSEL 1183 Query: 1460 AILRLKMHENANHYE----TMQKESEIERVKLIE------ELNVKITESVSLNKQVAELN 1509 + L+ N+ E T++++ LIE E + E +L ++VAEL+ Sbjct: 1184 SQALLEKQRNSEMIEQEMNTLREKIGESGKALIEKEQEKAEARQSVKEKETLRQKVAELS 1243 Query: 1510 KALEEEVAKTNEM 1522 +AL E+ + +EM Sbjct: 1244 QALLEK-QRNSEM 1255 Score = 99.1 bits (236), Expect = 9e-19 Identities = 199/1019 (19%), Positives = 418/1019 (41%), Gaps = 73/1019 (7%) Query: 170 TTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAME 229 T L+ +E ++K+ ++ +N A + ++++ ++ + E Sbjct: 516 TQHLEEKEIAHKKNSELQRENMALEQKVSELTQAEEHREKDIKFLQERLKELSQTLTENE 575 Query: 230 AEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXX 289 + KQ KD + VR+S L A + + E + L +E+E Sbjct: 576 IGTERIKQHAEKDTSALKVRVSELSAALTMRDTKELETLEQIKSLKREIESCEMALSDKE 635 Query: 290 XXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKL 349 +QS + + + E L A M++ ++ E + ++ +ELE+ L Sbjct: 636 KRAEDERRQSEKEISSVRQRVTE---LSEAIMSKEIQQEEREIEVRA-LKGRLEELEHAL 691 Query: 350 ATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKS-------PWSQLSSETLNQDTDKKI 402 +S+ V ++G LI R A K K ++ + +N+ + I Sbjct: 692 EESAEKSR-VERQIREGDTLIQRAELFGKALKEKERRHMDDHREKEMLRQRVNELSQDII 750 Query: 403 NKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEG 462 NK A+ E +++L + V+ + EK+ + + Q +E Sbjct: 751 NKERDAEEE--LKALRRKTVELRQTLIEKEEDKAEEQRRSENEKEALRHKATGLLQALEE 808 Query: 463 PSL-IHVGTNTEDVNEIAKVQEQLKQELND-EIKDVNVKDLI-EKLKSAEEQITQLNDEI 519 + V ++ A ++++++ E + E + ++ KD E L+ + + +E+ Sbjct: 809 ERMAAEVRQGRLEITSQALLEKEIETEKQEKERQTLDKKDREGETLQEEMAAVRRKREEL 868 Query: 520 DAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKG 579 A ++ + K + ++ +++ KV D ++ ++ E L ++V + + Sbjct: 869 GQALRDKEQEKCEADTQKEKENESLS--KKVKDLSQALLEKEREADILQEEVTAVRRKGE 926 Query: 580 NLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDE 639 L+ L D E D +K ++ E E + L + +E LQ++ Sbjct: 927 ELKQTLKDK------EQDKIEKEVQNEKEREALSLKVEHLSQALLEKEREADTLQEEVTA 980 Query: 640 VEDKLADISQLQSDQVCSEI-KSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKD 698 V K ++ Q D+ +I K V +++ +ALS K+L+ + + + + L + Sbjct: 981 VRRKGEELKQTLKDKEQKKIEKEVQNDKEKEALSQKVKQLSQALLEKEREADTLQEEVAA 1040 Query: 699 LENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGID-AKI 757 L E++ L+N QE+++ + EK EK ++ K+ H Q+ ++ + ++ K Sbjct: 1041 LRRKGEELKQTLKNKEQEHIEKEVQNEK---EKEAQ-SQKVEHLSQALLEKESEVELTKG 1096 Query: 758 QERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYT 817 ++ DL I+ +L ++ +LE + E+ R S K +L L K T Sbjct: 1097 KKEDLTIQ--IRDLRQF-----QLENEKEIKEEERQS-RLKVTELSETLINK-------T 1141 Query: 818 IQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNL---QISLSDMQQ 874 +QE+E +L V + ++ ++ E E E KE +K NQ + E +Q L Q + ++Q Sbjct: 1142 LQEEE--KQLEVKSLKGKTLKLKVKECEEEKKERKKLNQKVSELSQALLEKQRNSEMIEQ 1199 Query: 875 HYNALVEKANRTDLA----ESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEI 930 N L EK + A E E + + +++ E+ +++ Q L+ +K++ E +E Sbjct: 1200 EMNTLREKIGESGKALIEKEQEKAEARQSVKEKETLRQKVAELSQALL-EKQRNSEMIEQ 1258 Query: 931 EFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELID 990 E N+ E K EK ++ E E + Q K + E L V EL++ L Sbjct: 1259 EMNSLREKIGETGKAFIEKEQEKAE-----EGR-QSVKES-ETLRQKVAELSQALL---- 1307 Query: 991 KHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKL 1050 QK++ + +I +L L +K++EI Q+ ++ S+ + K Sbjct: 1308 ---QKERDVGQELV-SLREKIGELAQTLVKKEKEIKEGEQEKEEVKLKLTSLCQSLKEKE 1363 Query: 1051 AQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTE 1110 + ++ ++V + L EL R+ + + +ELK+ + + + + Sbjct: 1364 TEVELTGTELKATREKVGELRLVLINKERELNEEKRQSECEKEELKQRVESLSQALVEKD 1423 Query: 1111 GMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQ 1169 +I E + + A L++ + +E +QE+ LQ++ + E Q Sbjct: 1424 RALIEKE-EEVKEGAKQSKIEVEALRNQLVQLELAQAQE-MQEKGDLQDEKDRQAKEQQ 1480 Score = 89.8 bits (213), Expect = 5e-16 Identities = 194/1088 (17%), Positives = 434/1088 (39%), Gaps = 77/1088 (7%) Query: 49 ERQIKFERAQKCLENAALVSKRIKEHRKATAELLGRPFVPGISESLANTLKQKEILMEKI 108 ++ + +R LE + +EHR+ + L + L+ TL + EI E+I Sbjct: 527 KKNSELQRENMALEQKVSELTQAEEHREKDIKFLQERL-----KELSQTLTENEIGTERI 581 Query: 109 KQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNALSVLQVK---- 164 KQ+ E + V L + L I+ + ALS + + Sbjct: 582 KQHAEKDTSALKVRVSELSAALTMRDTKELETLEQIKSLKREIESCEMALSDKEKRAEDE 641 Query: 165 MKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQEN 224 + E I +++++ E + I +K ++ K + Sbjct: 642 RRQSEKEISSVRQRVTELSEAIMSKEIQQEEREIEVRALKGRLEELEHALEESAEKSRVE 701 Query: 225 FIAMEAEWKDEKQRLL-KDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXX 283 E + ++ L K ++ K+ R ++L E+S + ++ E+ Sbjct: 702 RQIREGDTLIQRAELFGKALKEKERRHMDDHREKEMLRQRVNELSQDIINKERDAEEELK 761 Query: 284 XXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNK 343 + E EE+ E + T L + +E E + ++RQ Sbjct: 762 ALRRKTVELRQTLIEKEEDKAEEQRRSENEKEALRHKATGLLQALE-EERMAAEVRQGRL 820 Query: 344 ELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQD-TDKKI 402 E+ ++ E + + +K + +K + + + E L Q DK+ Sbjct: 821 EITSQAL---LEKEIETEKQEKERQTLDKKDREGETLQEEMAAVRRKREELGQALRDKEQ 877 Query: 403 NKNEI-AKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHME 461 K E + E +SL+K + D + EK+ ++ I Q ++ + + Sbjct: 878 EKCEADTQKEKENESLSKKVKDLSQALLEKE------------READILQEEVTAVRR-K 924 Query: 462 GPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDA 521 G L T E K++++++ E E + V+ L + L E + L +E+ A Sbjct: 925 GEEL----KQTLKDKEQDKIEKEVQNEKEREALSLKVEHLSQALLEKEREADTLQEEVTA 980 Query: 522 ANKNMIKVKSNHKLK-LKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGN 580 + ++K K K K+++K + N + ++++ +L++ L ++ L+EE Sbjct: 981 VRRKGEELKQTLKDKEQKKIEKEVQNDKEKEALSQKVKQLSQALLEKEREADTLQEEVAA 1040 Query: 581 LQLHLVDY-DSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDE 639 L+ + + + E + +K ++ E E + + + L + E+ + + K ++ Sbjct: 1041 LRRKGEELKQTLKNKEQEHIEKEVQNEKEKEAQSQKVEHLSQALLEKESEVELTKGKKED 1100 Query: 640 VEDKLADISQLQ--------SDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQ 691 + ++ D+ Q Q ++ S +K L E + + ++E L +++LK + Sbjct: 1101 LTIQIRDLRQFQLENEKEIKEEERQSRLKVTELSETLINKTLQEEEKQLEVKSLK--GKT 1158 Query: 692 LYGTIKDLENDKEDIMNKLQNYIQENMDLTDKL--EKMSAEKISELLAKINHEEQSKIQT 749 L +K+ E +K++ Q + + L +K +M ++++ L KI ++ I+ Sbjct: 1159 LKLKVKECEEEKKERKKLNQKVSELSQALLEKQRNSEMIEQEMNTLREKIGESGKALIEK 1218 Query: 750 QFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEK 809 + A+ ++ E + ++++ + + + ++E SL K + G EK Sbjct: 1219 E-QEKAEARQSVKEKETLRQKVAELSQALLEKQRNSEMIEQEMNSLREKIGETGKAFIEK 1277 Query: 810 QKAYSE---YTIQEDELVNRLA-----VLMDHDRVVEKQLLEIEHENKEL-----QKKNQ 856 ++ +E +++E E + + L+ +R V ++L+ + + EL +K+ + Sbjct: 1278 EQEKAEEGRQSVKESETLRQKVAELSQALLQKERDVGQELVSLREKIGELAQTLVKKEKE 1337 Query: 857 ILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQT 916 I E + ++ L + +L EK +L +E + ++ +L L I E + Sbjct: 1338 IKEGEQEKEEVKLK-LTSLCQSLKEKETEVELTGTELKATREKVGEL--RLVLINKERE- 1393 Query: 917 LIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNM 976 + ++K++ E + E ++ES + L EK IE +++ ++ K +E L Sbjct: 1394 -LNEEKRQSECEKEELKQRVESL---SQALVEKDRALIEKEEEVKEGAKQSKIEVEALRN 1449 Query: 977 NVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQ 1036 + +L + + + Q + EQ I+E K L E II +++ + + Sbjct: 1450 QLVQLELAQAQEMQEKGDLQDEKDRQAKEQQISESEKERMAL---GERIIEISRDLKRRE 1506 Query: 1037 VSYMSMVSDYESKLAQFTTKLENME--EEMQRVSKQLLDSK---QHNEELQILVREQDDQ 1091 V + + S T + EN E + +R+ +L ++ +H E +I RE+ + Sbjct: 1507 VKQIKEEEESVSLQKIETLQKENKEGKQREERLKHRLRRTEMALRHTESEEIAWREKARE 1566 Query: 1092 IKELKETK 1099 ++ K Sbjct: 1567 LESKYRAK 1574 Score = 81.8 bits (193), Expect = 1e-13 Identities = 173/905 (19%), Positives = 364/905 (40%), Gaps = 76/905 (8%) Query: 658 EIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQEN 717 E +SVH Q++ + + +E + L + LE D +L+ ++ Sbjct: 20 ESRSVHA--QLETTREELRSMRSQVETADEVERSLRSQVATLEQDIRSTRLQLETSKEDT 77 Query: 718 MDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSR 777 +T +LE E+ + L +++ EE++ + +I+ I+ E+ELS +S Sbjct: 78 QSMTSRLEAQK-EEAAILRSQLEAEEETSQLKLKASEQEIKALRQQIQMSEAELSFVRSE 136 Query: 778 IC--RLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDR 835 + LE Y +E K+ +L QE + + +QE E LA H Sbjct: 137 LAGSTLEAESLKSRLETYEMEAKS-RLEDKKQELRISQRIERLQESEKELALAREQLHSE 195 Query: 836 VVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTK 895 + ++ + +H+ +E + ++L+ L+D+ L + +L + T+ Sbjct: 196 -LSAEIAKRQHQAQESE-------GAKESLEAELADVMGERERL-----QAELTQDSQTE 242 Query: 896 YQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIE 955 +T L +L EHQTL+ K+E+ E + N ++ R+ + L E ++ + Sbjct: 243 KETALYNL---------EHQTLM---KQEL-SRETQLNLTVQEREREIRSLKENIQR-AQ 288 Query: 956 YVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDY---TEQYINEIN 1012 + Q++E + + E M EE +++ L + + K + ++ E + EI Sbjct: 289 QENEAAEQIRECEKDRETA-MKAEESSRITLSEKGREISKMKESEKEHQFKMENALKEIE 347 Query: 1013 KLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKL--AQFTTKLENMEEEMQRVSKQ 1070 +L++KD + L Q++ + M+ + + L + ++ ++E +QR Sbjct: 348 SQTIILREKDTFLETLKQRLKECEEEIMNELQRQKHMLIVEERERDIKILQESVQREK-- 405 Query: 1071 LLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDX 1130 D +H + RE ++ KE + + + + I+ +++ D ++ Sbjct: 406 --DMVKHISDQWESQRESSERQKESTLIQHRLIVEERERDIKILQESVQRERDMVKHISD 463 Query: 1131 XXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDV 1190 K + E Q S +E+ A+L + + ++Q E L++ LT H + Sbjct: 464 QWESQRESAERQKENKISELSQALS-KKEREAELLERQTKRDSDLLQ-EQLDS-LTQH-L 519 Query: 1191 VNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADF 1250 +E ++ S+L++ N + +S + + + + EL Q L + E Sbjct: 520 EEKEIAHKKNSELQRENMALEQKVSELTQAEEHREKDIKFLQERLKEL-SQTLTENEIGT 578 Query: 1251 QKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQ 1310 ++ + SA + + +L ++ T +T ++ T+EQ+ SL+ +++ E L + + Sbjct: 579 ERIKQHAEKDTSALKVRVSELSAAL---TMRDTKELETLEQIKSLKREIESCEMALSDKE 635 Query: 1311 EKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQ---EQSI 1367 ++ D Q E S + ++R ++++ E+S Sbjct: 636 KRAEDERRQSEKEISSVRQRVTELSEAIMSKEIQQEEREIEVRALKGRLEELEHALEESA 695 Query: 1368 ------LNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTH 1421 I E + ++++ ++D K + L ++ +I K Sbjct: 696 EKSRVERQIREGDTLIQRAELFGKALKEKERRHMDDHREKEM-LRQRVNELSQDIINKER 754 Query: 1422 EYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLK-------MHENANHYE 1474 + L + +RQ L+E E+ + E+E LR K + E E Sbjct: 755 DAEEELKALRRKTVELRQTLIEKEEDKAEEQRRSENEKEALRHKATGLLQALEEERMAAE 814 Query: 1475 TMQKESEIERVKLIE---ELNVKITESVSLNKQVAELNKALEEEVA----KTNEMQTALE 1527 Q EI L+E E + E +L+K+ E + L+EE+A K E+ AL Sbjct: 815 VRQGRLEITSQALLEKEIETEKQEKERQTLDKKDRE-GETLQEEMAAVRRKREELGQALR 873 Query: 1528 NQEIE 1532 ++E E Sbjct: 874 DKEQE 878 Score = 67.7 bits (158), Expect = 2e-09 Identities = 142/831 (17%), Positives = 327/831 (39%), Gaps = 58/831 (6%) Query: 766 NIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVN 825 ++ ++L + + + + ++ SL + L ++ + + + Sbjct: 23 SVHAQLETTREELRSMRSQVETADEVERSLRSQVATLEQDIRSTRLQLETSKEDTQSMTS 82 Query: 826 RLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANR 885 RL + ++ QL E E E +L+ K + QI +S+ + + E A Sbjct: 83 RLEAQKEEAAILRSQL-EAEEETSQLKLKASEQEIKALRQQIQMSEAELSF-VRSELAGS 140 Query: 886 TDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEF---NTQIESAIRD 942 T E+ES K + + ++E+ + + + I Q+ + +++ E E Q+ S + Sbjct: 141 T--LEAESLKSRLETYEMEAKSRLEDKKQELRISQRIERLQESEKELALAREQLHSELSA 198 Query: 943 KKVLNEKYEKNIEYVTQ-LEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSP 1001 + + + E + LEA+L + E L + + ++ E +++ Q Sbjct: 199 EIAKRQHQAQESEGAKESLEAELADVMGERERLQAELTQDSQTEKETALYNLEHQTLM-- 256 Query: 1002 DYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVS------YMSMVSDYESKLAQFTT 1055 +Q ++ +LN +++++ EI +L + I AQ D E+ + + Sbjct: 257 ---KQELSRETQLNLTVQEREREIRSLKENIQRAQQENEAAEQIRECEKDRETAMKAEES 313 Query: 1056 KLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIIS 1115 + E+ + +SK K+H +++ ++E + Q L+E K TF + + Sbjct: 314 SRITLSEKGREISKMKESEKEHQFKMENALKEIESQTIILRE-KDTFLETLKQRLKECEE 372 Query: 1116 STIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKI 1175 + + + + VQ E++ ++ S Q +S + ++E Q+ Sbjct: 373 EIMNELQRQKHMLIVEERERDIKILQESVQREKDMVKHISD-QWESQRESSERQK----- 426 Query: 1176 IQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEI 1235 + L H ++ +E+ +K E + E D + + S SA Q+ +I Sbjct: 427 ------ESTLIQHRLIVEERERDIKILQESVQRERDMVKHISDQWESQRESAERQKENKI 480 Query: 1236 AELWKQHLAQREADFQKTEHE-------LRVQLSAFESKYEQLLDSVQSSTQEETNKIVT 1288 +EL Q L+++E + + E + L+ QL + E+ + + +++ + + Sbjct: 481 SEL-SQALSKKEREAELLERQTKRDSDLLQEQLDSLTQHLEEKEIAHKKNSELQRENMAL 539 Query: 1289 MEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXX 1348 ++V+ L + +E+ ++ LQE+ ++ + +EI E++ Sbjct: 540 EQKVSELTQAEEHREKDIKFLQERLKELSQ--TLTENEIGTERIKQHAEKDTSALKVRVS 597 Query: 1349 XXDLRTENQSYKQMQE-QSILNINEE----NAQLKKSSXXXXXXXXXXXXRVNDAEAKVL 1403 + K+++ + I ++ E L ++ +V Sbjct: 598 ELSAALTMRDTKELETLEQIKSLKREIESCEMALSDKEKRAEDERRQSEKEISSVRQRVT 657 Query: 1404 ELTHQLELKDSEIYQKTHEYTI-TLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAIL 1462 EL+ + K EI Q+ E + L R +E E+ ++ E + R+E +E + I Sbjct: 658 ELSEAIMSK--EIQQEEREIEVRALKGRLEELEHALEESAE-KSRVE--RQIREGDTLIQ 712 Query: 1463 RLKMHENA-NHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNE 1521 R ++ A E + E+ L + +N + ++ + E KAL + + Sbjct: 713 RAELFGKALKEKERRHMDDHREKEMLRQRVNELSQDIINKERDAEEELKALRRKTVELR- 771 Query: 1522 MQTALENQEIEIVTLNDEITNLQNMVRASSSKIQ--KHVSFASDTKQGRDE 1570 QT +E +E + + + ++ +Q + A++ +QGR E Sbjct: 772 -QTLIEKEEDKAEEQRRSENEKEALRHKATGLLQALEEERMAAEVRQGRLE 821 Score = 52.8 bits (121), Expect = 8e-05 Identities = 109/529 (20%), Positives = 215/529 (40%), Gaps = 60/529 (11%) Query: 1108 KTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTE 1167 K + I S E +++ +V ++ Q E ERS L+ Q A L + Sbjct: 4 KRKSYHIRSKHETAKEESRSVHAQLETTREELRSMRSQVETADEVERS-LRSQVATLEQD 62 Query: 1168 LQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLE-QLNTENDNLLSTVAE---LRSS 1223 ++ ++ + +T +E+ L+S+LE + T L ++ E LR Sbjct: 63 IRSTRLQLETSKEDTQSMTSRLEAQKEEAAILRSQLEAEEETSQLKLKASEQEIKALRQQ 122 Query: 1224 ISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEET 1283 I + + F +EL L + +E+ + S E K ++L S + +E+ Sbjct: 123 IQMSEAELSFVRSELAGSTLEAESLKSRLETYEMEAK-SRLEDKKQELRISQRIERLQES 181 Query: 1284 NKIVTME----------QVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVA 1333 K + + ++ Q++ Q+ E +L+ + ADV+ + E L++E+ + Sbjct: 182 EKELALAREQLHSELSAEIAKRQHQAQESEGAKESLEAELADVMGERERLQAELTQDSQT 241 Query: 1334 FXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXX 1393 +L E Q +QE+ E LK++ Sbjct: 242 EKETALYNLEHQTLMKQELSRETQLNLTVQERE-----REIRSLKEN--------IQRAQ 288 Query: 1394 RVNDAEAKVLELTHQLELKDSEIYQKTHEYT-ITLTQRNDEFENVRQQLVEYEKRIEDLT 1452 + N+A ++ E KD E K E + ITL+++ E +++ E++ ++E+ Sbjct: 289 QENEAAEQIRECE-----KDRETAMKAEESSRITLSEKGREISKMKESEKEHQFKMENAL 343 Query: 1453 YEKESELAILRLK---MHENANHYETMQKE--SEIERVK---LIE--ELNVKI-TESVSL 1501 E ES+ ILR K + + ++E +E++R K ++E E ++KI ESV Sbjct: 344 KEIESQTIILREKDTFLETLKQRLKECEEEIMNELQRQKHMLIVEERERDIKILQESVQR 403 Query: 1502 NKQVAELNKALEEEVAKTNEMQ---------TALENQEIEIVTLNDEITNLQNMVRASSS 1552 K + + E +++E Q +E +E +I L + + ++MV+ S Sbjct: 404 EKDMVKHISDQWESQRESSERQKESTLIQHRLIVEERERDIKILQESVQRERDMVKHISD 463 Query: 1553 KIQKHVSFASDTKQGRDEQLDNTMNK-----ELLDAVPRAELDLAMYML 1596 + + A K+ + +L ++K ELL+ + + DL L Sbjct: 464 QWESQRESAERQKENKISELSQALSKKEREAELLERQTKRDSDLLQEQL 512 >UniRef50_A0D4Y2 Cluster: Chromosome undetermined scaffold_38, whole genome shotgun sequence; n=1; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_38, whole genome shotgun sequence - Paramecium tetraurelia Length = 1239 Score = 129 bits (311), Expect = 7e-28 Identities = 213/966 (22%), Positives = 431/966 (44%), Gaps = 116/966 (12%) Query: 396 QDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLE 455 Q D I+ NE L +IQ N++L D ++ ++ + LI L + Sbjct: 276 QIIDFPISSNEY--LTQIIQEQNEELSDMTELLEQQQQEIQNKDLYVQQQQLLINDLLRK 333 Query: 456 HQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQ-ELNDEIKDVNVKDLIEKLKSAEEQITQ 514 ++ + + ++ E Q+ +KQ + N + +D+ +K+L ++ + + Q+ Sbjct: 334 LEEFVNCTNAFKKQLESQG-EEKKNYQQYIKQLDFNIKQQDLQIKNLQKEKEVYKRQVQS 392 Query: 515 LNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAEL 574 L + D K K++ + ++ M ++ S++ +++E L + L + Sbjct: 393 LQRDKDMYIKQNEKLRRQYDEDIQMMNSQLEQ-SQLLINDQECAELRQIKDQLQFDLEIA 451 Query: 575 EEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLV-QELHIL 633 + E NL+ LV S + + +E+ + ET+L +L S + + Q+L Sbjct: 452 KSEIQNLK-QLVYEISTEINVGFKFLGSLEVRQI-ETKLDIQTLCHSYRREYQKQKLQKE 509 Query: 634 QQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDA----LSASKKELAL--------- 680 Q ++D A I Q+ + E E+QI+ + +SKKE+AL Sbjct: 510 QGHLSILQDYKAQIFQINLQKSSLESIVAQQEKQINNYINDVVSSKKEIALICQEYEQKI 569 Query: 681 ---------VIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEK 731 V+ LK ++QL+ T L N +++ ++L+N I E+ + T LEK Sbjct: 570 AEVNDQKSVVLNELKQCEDQLFQTNLQLINQQQEFQSQLRNKILEHNEQTTDLEKSL--- 626 Query: 732 ISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDR 791 +QSKI+ +F + +I ++ E E+ KY L+E I ++ Sbjct: 627 -----------QQSKIEHEF-LKKQIHDK-------EKEIEKYSLNSKELQEQIIRLDQE 667 Query: 792 RYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKEL 851 + +L+ ++ ++K + Q D+ +++ L + +QL + + +E Sbjct: 668 KKTLQHSIQNSDKLIELEKKQLEQ---QRDQNQHKILELQTQVEQITEQLSQQMNLFEEQ 724 Query: 852 QKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRIT 911 Q++NQ L+E+ + Q +Q Y+ ++++ E TK Q L++ +++ Sbjct: 725 QQENQNLIEQIEKYQ----QKEQEYDFILQQQE-----ELSQTKQQ-----LQNQIQQ-- 768 Query: 912 HEHQTLIVQK-KKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNN 970 HE+Q IVQ E++ Q +S ++ +LN++ + V QL+ Q+++N Sbjct: 769 HENQLQIVQNLYDELKISHENSKHQNDSLQQEIDLLNQQLLDSKNEVEQLKQMQQQFENL 828 Query: 971 IENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEI--IAL 1028 I LN +EE N+ N D +QQ Q + + +N+IN+L +++ E I I Sbjct: 829 ILQLNEQIEEQNQ-NQNQTD---LQQQLQEEIHNK--VNQINQLTEQIEELTENIRQIKD 882 Query: 1029 NQKINNAQVSYMSMV--SDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVR 1086 N + AQ+ + + + + Q T L N++ + S++L + +Q+ + R Sbjct: 883 NNAVEIAQIQQQHTIELNGKKEVIIQLETSLHNLQHQNSVNSQELANLQQYAQN----ER 938 Query: 1087 EQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQ- 1145 Q Q E+++ +L ++ E + ++S I +S + ++ + Sbjct: 939 SQQQQETEIEKQQLKLQITSFNEERVTLNSQITQLSQQVEHYSNLNSQLTQKIEEIQQKL 998 Query: 1146 EEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQ 1205 +++ Q+ S +Q N E QE Q+ L EL VV QE+ +Q ++ E+ Sbjct: 999 SDQQSQQQPSNKVDQQEYRNLE-QENQDLTDQISKLLEEL---GVVEQER-SQKEADNEE 1053 Query: 1206 LNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFE 1265 L + + L+T+AELRS + +++++L + H FQ + E L Sbjct: 1054 LKIQYEQALNTIAELRS--------KEYDVSQLKQSH-----NQFQTLQDE-NTNLKQLY 1099 Query: 1266 SKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRS 1325 ++ +L+D + QE+ EQ + N LQ+++E+ + L+ KY ++I + + L S Sbjct: 1100 AQKLKLVDQLNKQIQEQ-------EQ--QMNNYLQNEQEY-QKLKVKYQELIIEKDQLSS 1149 Query: 1326 EIEDEK 1331 +IE ++ Sbjct: 1150 QIEKQQ 1155 Score = 120 bits (290), Expect = 3e-25 Identities = 216/1120 (19%), Positives = 466/1120 (41%), Gaps = 97/1120 (8%) Query: 487 QELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKT-ID 545 Q N++ + +D ++L+ EQ QL + +N ++N ++ + Q + I Sbjct: 107 QTNNNQTLNQQQQDQPKQLEKQPEQEKQLEQNESSQQRN---TQNNPQIAVSQPKANQIS 163 Query: 546 NFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEM 605 N ++ SN + ++L L Q+V +L E L L + + + Sbjct: 164 NQPEIQQSNHHVNN--QQLVVLQQQVLQLATENKELSSQLQELCKAY---NQLILNYDSC 218 Query: 606 ENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLE 665 N +T KA+ L ++ +L Q + L K + ++ D+ Q + + ++ Sbjct: 219 NNFIQTLPKAL-LPQNYMDNLDQNMKYL--KLFQPQNISLDLQQFNLNLLKNQTHVFVPP 275 Query: 666 EQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENM----DLT 721 + ID +S + L +I+ E+L + LE +++I NK Y+Q+ DL Sbjct: 276 QIIDFPISSNEYLTQIIQE---QNEELSDMTELLEQQQQEIQNK-DLYVQQQQLLINDLL 331 Query: 722 DKLEKM--SAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRIC 779 KLE+ + L E+++ Q +D I+++DL I+N++ E YK ++ Sbjct: 332 RKLEEFVNCTNAFKKQLESQGEEKKNYQQYIKQLDFNIKQQDLQIKNLQKEKEVYKRQVQ 391 Query: 780 RLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEK 839 L+ + + L R+ D+ + Q S+ I + E R ++ Sbjct: 392 SLQRDKDMYIKQNEKLRRQYDE-DIQMMNSQLEQSQLLINDQECAEL--------RQIKD 442 Query: 840 QL-LEIEHENKELQKKNQILLEENQNLQISLSDM-QQHYNALVEKANRTDLAESESTKYQ 897 QL ++E E+Q Q++ E + + + + + K + L S +YQ Sbjct: 443 QLQFDLEIAKSEIQNLKQLVYEISTEINVGFKFLGSLEVRQIETKLDIQTLCHSYRREYQ 502 Query: 898 TQLRDLESNLKRITHEHQTLIVQ---KKKEIEDL----EIEFNTQIESAIRDKK---VLN 947 Q E I +++ I Q +K +E + E + N I + KK ++ Sbjct: 503 KQKLQKEQGHLSILQDYKAQIFQINLQKSSLESIVAQQEKQINNYINDVVSSKKEIALIC 562 Query: 948 EKYEKNIEYVTQLEAQL---------QEYKNNIENLNMNVEELNKMNLELIDKH-----V 993 ++YE+ I V ++ + Q ++ N++ +N E +++ ++++ + + Sbjct: 563 QEYEQKIAEVNDQKSVVLNELKQCEDQLFQTNLQLINQQQEFQSQLRNKILEHNEQTTDL 622 Query: 994 QKQQTQSP---DYTEQYIN----EINKLNALLKQKDEEIIALNQKINNAQVSYMSM---- 1042 +K QS ++ ++ I+ EI K + K+ E+II L+Q+ Q S + Sbjct: 623 EKSLQQSKIEHEFLKKQIHDKEKEIEKYSLNSKELQEQIIRLDQEKKTLQHSIQNSDKLI 682 Query: 1043 ---VSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETK 1099 E + Q K+ ++ +++++++QL EE Q + +QI++ ++ + Sbjct: 683 ELEKKQLEQQRDQNQHKILELQTQVEQITEQLSQQMNLFEEQQQENQNLIEQIEKYQQKE 742 Query: 1100 LTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQE 1159 ++ + + E +S T + + + + LK+ E Q S LQ+ Sbjct: 743 QEYDFILQQQEE--LSQTKQQLQNQIQQHENQLQIVQNLYDELKISHENSKHQNDS-LQQ 799 Query: 1160 QSAKLNTELQECYTKIIQLETL-----NTELTGHDVVNQEQINQLKSKL-EQLNTENDN- 1212 + LN +L + ++ QL+ + N L ++ + ++ NQ ++ L +QL E N Sbjct: 800 EIDLLNQQLLDSKNEVEQLKQMQQQFENLILQLNEQIEEQNQNQNQTDLQQQLQEEIHNK 859 Query: 1213 ------LLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFES 1266 L + EL +I D EIA++ +QH + K E ++++ S Sbjct: 860 VNQINQLTEQIEELTENIRQIKDNNAVEIAQIQQQHTIELNG---KKEVIIQLETSLHNL 916 Query: 1267 KYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSE 1326 +++ ++S + + ++ + +Q + + Q + + + E+ + +QI L + Sbjct: 917 QHQNSVNSQELANLQQYAQNERSQQQQETEIEKQQLKLQITSFNEERVTLNSQITQLSQQ 976 Query: 1327 IEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXX 1386 +E D +++ Q ++ +Q N+ +EN L Sbjct: 977 VEHYS-NLNSQLTQKIEEIQQKLSDQQSQQQPSNKVDQQEYRNLEQENQDLTDQISKLLE 1035 Query: 1387 XXXXXXXRVNDAEAKVLELTHQLELKDSEIYQ-KTHEYTIT-LTQRNDEFENVRQQLVEY 1444 + EA EL Q E + I + ++ EY ++ L Q +++F+ ++ + Sbjct: 1036 ELGVVEQERSQKEADNEELKIQYEQALNTIAELRSKEYDVSQLKQSHNQFQTLQDENTNL 1095 Query: 1445 EKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKL-IEELNVKITESVSLNK 1503 K++ + +L + + N+Y +Q E E +++K+ +EL ++ + S + Sbjct: 1096 -KQLYAQKLKLVDQLNKQIQEQEQQMNNY--LQNEQEYQKLKVKYQELIIEKDQLSSQIE 1152 Query: 1504 QVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNL 1543 + + + +E+ E L+ E EI LN +I L Sbjct: 1153 KQQQTSSKIEDTKEFIVEQNLKLQRMEQEIAGLNSKILQL 1192 Score = 94.3 bits (224), Expect = 2e-17 Identities = 141/808 (17%), Positives = 345/808 (42%), Gaps = 83/808 (10%) Query: 815 EYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQ 874 ++ I +E + + ++ + + + +E + +E+Q K+ + ++ + L +++ Sbjct: 279 DFPISSNEYLTQ--IIQEQNEELSDMTELLEQQQQEIQNKDLYVQQQQLLINDLLRKLEE 336 Query: 875 HYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIE-FN 933 N + + E YQ ++ L+ N+K+ + Q +QK+KE+ +++ Sbjct: 337 FVNCTNAFKKQLESQGEEKKNYQQYIKQLDFNIKQ--QDLQIKNLQKEKEVYKRQVQSLQ 394 Query: 934 TQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMN-VEELNKMNLELIDKH 992 + I+ + L +Y+++I+ + Q Q N+ E + +++ + +LE+ Sbjct: 395 RDKDMYIKQNEKLRRQYDEDIQMMNSQLEQSQLLINDQECAELRQIKDQLQFDLEIAKSE 454 Query: 993 VQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALN------------QKINNAQVSYM 1040 +Q + + + + L +L ++ E + + QK+ Q ++ Sbjct: 455 IQNLKQLVYEISTEINVGFKFLGSLEVRQIETKLDIQTLCHSYRREYQKQKLQKEQ-GHL 513 Query: 1041 SMVSDYESKLAQFTTKLENME----EEMQRVSKQLLDSKQHNEELQILVREQDDQIKELK 1096 S++ DY++++ Q + ++E ++ ++++ + D +E+ ++ +E + +I E+ Sbjct: 514 SILQDYKAQIFQINLQKSSLESIVAQQEKQINNYINDVVSSKKEIALICQEYEQKIAEVN 573 Query: 1097 ETKLTFEMNIPKTEGMIISSTIEPMSDDA-------NNVDXXXXXXXXXXXXLKVQE-EE 1148 + K + + E + + ++ ++ N + L+ + E Sbjct: 574 DQKSVVLNELKQCEDQLFQTNLQLINQQQEFQSQLRNKILEHNEQTTDLEKSLQQSKIEH 633 Query: 1149 EFIQERSVLQEQSA-KLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLN 1207 EF++++ +E+ K + +E +II+L+ L H + N +++ +L+ K QL Sbjct: 634 EFLKKQIHDKEKEIEKYSLNSKELQEQIIRLDQEKKTLQ-HSIQNSDKLIELEKK--QLE 690 Query: 1208 TENDNLLSTVAELRSSISSAVDQRG-----FEIAELWKQHLAQREADFQKTEHELRVQLS 1262 + D + EL++ + +Q FE + Q+L ++ +Q+ E E L Sbjct: 691 QQRDQNQHKILELQTQVEQITEQLSQQMNLFEEQQQENQNLIEQIEKYQQKEQEYDFILQ 750 Query: 1263 AFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEI 1322 E + Q +Q+ Q+ N++ ++ + + +H + ++ D++NQ ++ Sbjct: 751 QQE-ELSQTKQQLQNQIQQHENQLQIVQNLYDELKISHENSKHQNDSLQQEIDLLNQ-QL 808 Query: 1323 LRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSX 1382 L S+ E E++ + + +NQ+ +Q+Q I+ + Q Sbjct: 809 LDSKNEVEQLKQMQQQFENLILQLNEQIEEQNQNQNQTDLQQQLQEEIHNKVNQ------ 862 Query: 1383 XXXXXXXXXXXRVNDAEAKVLELTHQL-ELKDS---EIYQKTHEYTITLTQRNDEFENVR 1438 +N ++ ELT + ++KD+ EI Q ++TI L + + Sbjct: 863 ------------INQLTEQIEELTENIRQIKDNNAVEIAQIQQQHTIELNGK-------K 903 Query: 1439 QQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITES 1498 + +++ E + +L ++ L N Q+E+EIE+ +L ++ E Sbjct: 904 EVIIQLETSLHNLQHQNSVNSQELANLQQYAQNERSQQQQETEIEKQQLKLQITSFNEER 963 Query: 1499 VSLNKQVAELNKALE-------EEVAKTNEMQTALENQEIEIVTLN----DEITNLQNMV 1547 V+LN Q+ +L++ +E + K E+Q L +Q+ + N E NL+ Sbjct: 964 VTLNSQITQLSQQVEHYSNLNSQLTQKIEEIQQKLSDQQSQQQPSNKVDQQEYRNLEQEN 1023 Query: 1548 RASSSKIQKHVSFASDTKQGRDE-QLDN 1574 + + +I K + +Q R + + DN Sbjct: 1024 QDLTDQISKLLEELGVVEQERSQKEADN 1051 Score = 86.2 bits (204), Expect = 7e-15 Identities = 92/415 (22%), Positives = 205/415 (49%), Gaps = 39/415 (9%) Query: 446 DTLIAQLQLEHQQHMEGPSLIHVGTNTEDV--NEIAKVQEQLKQELNDEIKDVNVKDLIE 503 D+L ++ L +QQ ++ + + + N I ++ EQ++++ ++ + + L E Sbjct: 795 DSLQQEIDLLNQQLLDSKNEVEQLKQMQQQFENLILQLNEQIEEQNQNQNQTDLQQQLQE 854 Query: 504 KLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEE 563 ++ + QI QL ++I+ +N+ ++K N+ +++ Q+Q+ + +++ + I++L Sbjct: 855 EIHNKVNQINQLTEQIEELTENIRQIKDNNAVEIAQIQQ--QHTIELNGKKEVIIQLETS 912 Query: 564 LHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEME--NLAETRLKAISLLE- 620 LH+L + + +E NLQ + + S + E+++ K+ ++++ + E R+ S + Sbjct: 913 LHNLQHQNSVNSQELANLQQYAQNERSQQQQETEIEKQQLKLQITSFNEERVTLNSQITQ 972 Query: 621 -SQKFDLVQELHI-LQQKYDEVEDKLAD-ISQLQSDQVCSEIKSVHLEEQ----IDALSA 673 SQ+ + L+ L QK +E++ KL+D SQ Q + + +LE++ D +S Sbjct: 973 LSQQVEHYSNLNSQLTQKIEEIQQKLSDQQSQQQPSNKVDQQEYRNLEQENQDLTDQISK 1032 Query: 674 SKKELALV----------IENLKLDKEQLYGTIKDLENDKEDI--MNKLQNYIQENMDLT 721 +EL +V E LK+ EQ TI +L + + D+ + + N Q D Sbjct: 1033 LLEELGVVEQERSQKEADNEELKIQYEQALNTIAELRSKEYDVSQLKQSHNQFQTLQDEN 1092 Query: 722 DKLEKMSAEK---ISELLAKINHEEQ---SKIQTQFGID-AKIQERDLYIE--NIESELS 772 L+++ A+K + +L +I +EQ + +Q + K++ ++L IE + S++ Sbjct: 1093 TNLKQLYAQKLKLVDQLNKQIQEQEQQMNNYLQNEQEYQKLKVKYQELIIEKDQLSSQIE 1152 Query: 773 KYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRL 827 K + ++E++ + ++ L+R ++ L K + T Q DE +L Sbjct: 1153 KQQQTSSKIEDTKEFIVEQNLKLQRMEQEIAG-LNSK---ILQLTAQRDEYKEQL 1203 Score = 47.6 bits (108), Expect = 0.003 Identities = 86/453 (18%), Positives = 194/453 (42%), Gaps = 52/453 (11%) Query: 143 DVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXX 202 ++ L+ + + N + L+ + E IL L E+I E++Q N+ T Sbjct: 800 EIDLLNQQLLDSKNEVEQLKQMQQQFENLILQLNEQIEEQNQ-----NQNQTDLQQQLQE 854 Query: 203 XXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKD-VRISSLEEANKLLE 261 +Q+ ++ EN + KD + I+ + + ++ +E LE Sbjct: 855 EIHNKVNQINQLTEQIEELTENI----RQIKDNNAVEIAQIQQQHTIELNGKKEVIIQLE 910 Query: 262 AARFEISLEHSKLAQEL---EQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEI 318 + + ++S +QEL +Q + KQ ++ E E+ +L Sbjct: 911 TSLHNLQHQNSVNSQELANLQQYAQNERSQQQQETEIEKQQLKLQITSFNE--ERVTLN- 967 Query: 319 ANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNT 378 + +T+L++++E +LN Q+ Q +E++ KL ++ ++ PS K + ++ RN Sbjct: 968 SQITQLSQQVEHYSNLNSQLTQKIEEIQQKL----SDQQSQQQPSNK----VDQQEYRNL 1019 Query: 379 ASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXX 438 E NQD +I+K + +L +V Q ++ D E + + + Sbjct: 1020 -------------EQENQDLTDQISK-LLEELGVVEQERSQKEADNEELKIQYE-QALNT 1064 Query: 439 XXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDV-NEIAKVQEQLKQELNDEIKDVN 497 K+ ++QL+ H Q +L TN + + + K+ +QL +++ ++ + +N Sbjct: 1065 IAELRSKEYDVSQLKQSHNQFQ---TLQDENTNLKQLYAQKLKLVDQLNKQIQEQEQQMN 1121 Query: 498 ----VKDLIEKLKSAEEQI----TQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSK 549 + +KLK +++ QL+ +I+ + K++ + ++Q K + Sbjct: 1122 NYLQNEQEYQKLKVKYQELIIEKDQLSSQIEKQQQTSSKIEDTKEFIVEQNLKLQRMEQE 1181 Query: 550 VSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQ 582 ++ N +I++LT + +++ E +++ N Q Sbjct: 1182 IAGLNSKILQLTAQRDEYKEQL-EFKQKNANSQ 1213 >UniRef50_Q23E34 Cluster: Putative uncharacterized protein; n=2; Tetrahymena thermophila SB210|Rep: Putative uncharacterized protein - Tetrahymena thermophila SB210 Length = 3482 Score = 128 bits (310), Expect = 9e-28 Identities = 207/1056 (19%), Positives = 446/1056 (42%), Gaps = 106/1056 (10%) Query: 337 QIRQTNKELENKLATMGTESKAVSSPSKKGSP-------LISRKSGRNTASKMKSPWSQL 389 Q +Q+N++ +N+L + T A S+P+ + +ISR + ++ Sbjct: 2446 QFQQSNQQNQNQLESSRTLRSASSNPNIAANTQPIQLQYVISRNQLNQPQQQQQANIIPD 2505 Query: 390 SSETLNQDTDK-KINKNEIAKLEMVIQSLNKDLVD--KEYVISEKDTXXXXXXXXXXG-- 444 +S+ +NQ +K +I +N I++L+ + +++ K + ++ + E+++ G Sbjct: 2506 NSKQINQQVNKNQILRNSISQLKNIDENIQKQIKSNVEDKMQQEQNSSLHSETFSLNGTF 2565 Query: 445 --KDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQL------KQELNDEIKDV 496 ++ + L++ + + ++ + + E+ + QL KQ D++K Sbjct: 2566 DQTREILKERNLQNMINTASKNFSKAQSHEQKIIELQTDRSQLLKMIATKQLEIDDLKQK 2625 Query: 497 NVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKE 556 N ++ I L +++ + N++++ N+ + + ++ Q K + ++ +++ N+ Sbjct: 2626 NNQEAI--LIQRIDKLVEENEQLNFQNQKLAQDYQQLNERVNQNLKYMKEYNLLNEENQS 2683 Query: 557 IVRLTEELHHLSQKV---AELEEEKGNLQLHLVDYDSGRMIE---------SDVYKKMIE 604 + TEE L K+ + + N L +++ + IE S M + Sbjct: 2684 LCEKTEEYQELLDKLEIKITILSNENNTLLKMME-EKQEQIELLKQREEEHSQSQNSMTK 2742 Query: 605 MENLAETRLKAISLLESQKFDLVQELHILQ-----QKYDEVEDKLAD------------I 647 ++L E + + I LE Q + ++ +L Q+ EDKL + I Sbjct: 2743 FQDLLEKKNQLIKQLEKQLREAQEQNKVLNNEIIFQQEQFTEDKLNEAVSNIVSEKNTLI 2802 Query: 648 SQLQSDQVCSEIKSVHLEEQIDALS---ASKKELALVIENLKLDKEQLYGTIKDLENDKE 704 Q+ ++ +IK L E+ +L A + + + LK KE + + D++ Sbjct: 2803 EQISAENSNFKIKIKSLLEENKSLQEKVAKQNAIEWYADQLKTTKETI--EENQMIKDRQ 2860 Query: 705 DIMNK-LQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKI-QTQFGIDAKIQERDL 762 I NK L +++ +DL + ++ KI +L + E+++ + +T+ I+ K++E Sbjct: 2861 LIENKELIQEMKKIIDLNKEQLELKENKILQLKQTYDKEKEAILRETEHQINEKLEEIKA 2920 Query: 763 YIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYL--QEKQKAYSEYTIQE 820 Y IE K++ + ++ + ME++ + + DQ Y+ QE QK E I Sbjct: 2921 YTLEIE----KFRDELVLTKKQL--MEEKNRA-DYFQDQFKIYMGNQEHQKFQQEQIIMN 2973 Query: 821 DELVNRLAVLMDHDRV-VEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQH-YNA 878 L N+ + D++ ++ +++++N + K ++ N NL L + Q Sbjct: 2974 TCLENKRS---QQDKIHFLNEIEDLKNKNIAVTDKLDQMIAVNDNLTEVLKEKSQEIQEL 3030 Query: 879 LVEKANRTDLAESES---TKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQ 935 L+EK E E + Q L LE + E Q + K+K + Q Sbjct: 3031 LIEKDKLLYEREQEQIQLERIQNNLHQLEEERENFLKETQDVYELKEKVSHQETNRYKQQ 3090 Query: 936 IES---AIRDKKV-LNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDK 991 IE I+ K+ NE+++KN+ + Q + ++ + K+ I LN + ++ + I + Sbjct: 3091 IEDLKLQIQQKEFETNEQFQKNLNQLEQSQQEIIQLKDQINKLNYQISQIQSEDRLKIQE 3150 Query: 992 HVQ------KQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSD 1045 V + Q + D + N +KL L Q+D+ L+++ + + + Sbjct: 3151 RVHFDSTLLELQKINEDNQIEIANLKDKLLKLENQRDKLQRQLSEEKEENDLKFRKSEQN 3210 Query: 1046 YESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMN 1105 YE+++A TK + + +E + +S+ KQ EL E ++K K+ + Sbjct: 3211 YENQIASLDTKYKRLLDEFKYLSESYEHKKQ---ELNQFKEELPQIANKIKNEKIELTKS 3267 Query: 1106 IPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLN 1165 I + E + +I+ N V + + + E+ LQ Q L Sbjct: 3268 IEEKEKQLDILSIQ------NKVSNEKILDLESQVNIMINKNEQIQNTYLALQTQYQVLE 3321 Query: 1166 TELQECYTKIIQLETLNTELTGHDVVN----QEQINQLKSKLEQLNTENDNLLSTVAELR 1221 + + + KI QLE N H ++ + Q++Q K ++ +L T+N L+ ++ Sbjct: 3322 NKYTQQHKKIQQLEKQNDNTKSHLTISLQQAETQLSQTKMQIIELETKNKRLIDDISRAN 3381 Query: 1222 SSISSAVDQR-----GF--EIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDS 1274 DQ F E+ E+ ++ + F++ + EL ++ ++ QL Sbjct: 3382 HLKQLMKDQMEDLEINFKKEMDEVREESIKDLNNKFEREKRELNFKIQKLGNQVRQLESD 3441 Query: 1275 VQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQ 1310 Q+ K +E +T ++ ++E++L Q Sbjct: 3442 KDIMKQDLDAKQREVESITLQLQRVAEREKNLYQKQ 3477 Score = 120 bits (289), Expect = 3e-25 Identities = 196/1012 (19%), Positives = 440/1012 (43%), Gaps = 77/1012 (7%) Query: 538 KQMQKTIDNFSKVSDSNKEIVRLTEELH-HLSQKVAELEEEKGNLQLHLVDYD-SGRMIE 595 KQ+ + ++ + +S ++ + E + + V + +++ N LH + +G + Sbjct: 2508 KQINQQVNKNQILRNSISQLKNIDENIQKQIKSNVEDKMQQEQNSSLHSETFSLNGTFDQ 2567 Query: 596 SDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQV 655 + K ++N+ T K S +S + +++ Q + K +I L+ Sbjct: 2568 TREILKERNLQNMINTASKNFSKAQSHEQKIIELQTDRSQLLKMIATKQLEIDDLKQKNN 2627 Query: 656 CSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQ 715 I L ++ID L ++L + L D +QL + N M + + Sbjct: 2628 QEAI----LIQRIDKLVEENEQLNFQNQKLAQDYQQLNERV----NQNLKYMKEYNLLNE 2679 Query: 716 ENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYK 775 EN L +K E+ E + +L KI T + + QE+ ++ E E S+ + Sbjct: 2680 ENQSLCEKTEEYQ-ELLDKLEIKITILSNEN-NTLLKMMEEKQEQIELLKQREEEHSQSQ 2737 Query: 776 SRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDR 835 + + + ++ ++E + +++ QL ++ + +E Q+++ + Sbjct: 2738 NSMTKFQD---LLEKKNQLIKQLEKQLREAQEQNKVLNNEIIFQQEQFTEDKLNEAVSNI 2794 Query: 836 VVEKQLL--EIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESES 893 V EK L +I EN + K + LLEEN++LQ ++ NA+ A++ + E+ Sbjct: 2795 VSEKNTLIEQISAENSNFKIKIKSLLEENKSLQEKVAKQ----NAIEWYADQLKTTK-ET 2849 Query: 894 TKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEK--YE 951 + ++D R E++ LI Q+ K+I DL E Q+E +++ K+L K Y+ Sbjct: 2850 IEENQMIKD------RQLIENKELI-QEMKKIIDLNKE---QLE--LKENKILQLKQTYD 2897 Query: 952 KNIEYVT-QLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINE 1010 K E + + E Q+ E I+ + +E+ L L K + +++ ++ + +Q+ + Sbjct: 2898 KEKEAILRETEHQINEKLEEIKAYTLEIEKFRD-ELVLTKKQLMEEKNRADYFQDQF--K 2954 Query: 1011 INKLNALLKQKDEEIIALNQKINNAQ-----VSYMSMVSDYESKLAQFTTKLENMEEEMQ 1065 I N ++ +E I +N + N + + +++ + D ++K T KL+ M Sbjct: 2955 IYMGNQEHQKFQQEQIIMNTCLENKRSQQDKIHFLNEIEDLKNKNIAVTDKLDQMIAVND 3014 Query: 1066 RVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEM---NIPKTEGM---IISST-- 1117 +++ L K+ ++E+Q L+ E+D + E ++ ++ E N+ + E + T Sbjct: 3015 NLTEVL---KEKSQEIQELLIEKDKLLYEREQEQIQLERIQNNLHQLEEERENFLKETQD 3071 Query: 1118 IEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQ 1177 + + + ++ + L++Q++E E+ Q+ +L QE Q Sbjct: 3072 VYELKEKVSHQETNRYKQQIEDLKLQIQQKEFETNEQ--FQKNLNQLEQSQQEIIQLKDQ 3129 Query: 1178 LETLN---TELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFE 1234 + LN +++ D + ++ S L +L N++ +A L+ + +QR + Sbjct: 3130 INKLNYQISQIQSEDRLKIQERVHFDSTLLELQKINEDNQIEIANLKDKLLKLENQRD-K 3188 Query: 1235 IAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTM----E 1290 + + + + F+K+E Q+++ ++KY++LLD + ++ +K + E Sbjct: 3189 LQRQLSEEKEENDLKFRKSEQNYENQIASLDTKYKRLLDEFKYLSESYEHKKQELNQFKE 3248 Query: 1291 QVTSLQNKLQ-DKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXX 1349 ++ + NK++ +K E ++++EK + I +++++ +EK+ Sbjct: 3249 ELPQIANKIKNEKIELTKSIEEKEKQL--DILSIQNKVSNEKILDLESQVNIMINKNEQI 3306 Query: 1350 XD----LRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLEL 1405 + L+T+ Q + Q I + Q + +++ + +++EL Sbjct: 3307 QNTYLALQTQYQVLENKYTQQHKKIQQLEKQNDNTKSHLTISLQQAETQLSQTKMQIIEL 3366 Query: 1406 THQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEY-EKRIEDLTYEKESELAILRL 1464 + + +I + H + Q D N ++++ E E+ I+DL + E E L Sbjct: 3367 ETKNKRLIDDISRANHLKQLMKDQMEDLEINFKKEMDEVREESIKDLNNKFEREKRELNF 3426 Query: 1465 KMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQ-VAELNKALEEE 1515 K+ + N ++ + +I + L + + ES++L Q VAE K L ++ Sbjct: 3427 KIQKLGNQVRQLESDKDIMKQDL--DAKQREVESITLQLQRVAEREKNLYQK 3476 Score = 109 bits (261), Expect = 8e-22 Identities = 181/908 (19%), Positives = 401/908 (44%), Gaps = 64/908 (7%) Query: 231 EWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXX 290 E + ++ +LLK I +K + I L++ N EA + KL +E EQ Sbjct: 2600 ELQTDRSQLLKMIATKQLEIDDLKQKNNQ-EAILIQ---RIDKLVEENEQLNFQNQKLAQ 2655 Query: 291 XXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKI-ELLEHLNCQIRQTNKELENKL 349 L + + + + E E ++ E T++ ELL+ L +I + E L Sbjct: 2656 DYQQL-NERVNQNLKYMKEYNLLNE-ENQSLCEKTEEYQELLDKLEIKITILSNENNTLL 2713 Query: 350 ATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAK 409 M + + + L+ ++ ++ S+ Q E NQ K++ K ++ + Sbjct: 2714 KMMEEKQEQIE--------LLKQREEEHSQSQNSMTKFQDLLEKKNQ-LIKQLEK-QLRE 2763 Query: 410 LEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQH-MEGPSLIHV 468 + + LN +++ ++ +E D K+TLI Q+ E+ ++ SL+ Sbjct: 2764 AQEQNKVLNNEIIFQQEQFTE-DKLNEAVSNIVSEKNTLIEQISAENSNFKIKIKSLLEE 2822 Query: 469 GTNTEDV----NEIAKVQEQLK--QELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAA 522 + ++ N I +QLK +E +E + + + LIE +E I ++ ID Sbjct: 2823 NKSLQEKVAKQNAIEWYADQLKTTKETIEENQMIKDRQLIEN----KELIQEMKKIIDL- 2877 Query: 523 NKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQ 582 NK +++K N L+LKQ + + + ++ +I EE+ + ++ + +E + Sbjct: 2878 NKEQLELKENKILQLKQTYDK-EKEAILRETEHQINEKLEEIKAYTLEIEKFRDELVLTK 2936 Query: 583 LHLVDYDSGRMIESDVYKKMI---EMENLAETRLKAISLLESQKFDLVQELHILQQKYDE 639 L++ + D +K + E + + ++ + LE+++ ++H L + D Sbjct: 2937 KQLMEEKNRADYFQDQFKIYMGNQEHQKFQQEQIIMNTCLENKRSQQ-DKIHFLNEIEDL 2995 Query: 640 VEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDL 699 +A +L DQ+ + + +L E + S +EL + + L ++EQ ++ + Sbjct: 2996 KNKNIAVTDKL--DQMIAV--NDNLTEVLKEKSQEIQELLIEKDKLLYEREQEQIQLERI 3051 Query: 700 ENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQE 759 +N+ + + +N+++E D+ + EK+S ++ + +I + Q +F + + Q+ Sbjct: 3052 QNNLHQLEEERENFLKETQDVYELKEKVSHQETNRYKQQIEDLKLQIQQKEFETNEQFQK 3111 Query: 760 RDLYIENIESELSKYKSRICRLEESIA-VMEDRRYSLERKADQLGSYLQEKQKAYSEYTI 818 +E + E+ + K +I +L I+ + + R ++ + S L E QK + I Sbjct: 3112 NLNQLEQSQQEIIQLKDQINKLNYQISQIQSEDRLKIQERV-HFDSTLLELQKINEDNQI 3170 Query: 819 QEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNA 878 + L ++L L + +++QL E + EN +K++ QN + ++ + Y Sbjct: 3171 EIANLKDKLLKLENQRDKLQRQLSEEKEENDLKFRKSE------QNYENQIASLDTKYKR 3224 Query: 879 LVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFN-TQIE 937 L+++ L+ES K Q +L + L +I ++ + ++ K IE+ E + + I+ Sbjct: 3225 LLDEFKY--LSESYEHKKQ-ELNQFKEELPQIANKIKNEKIELTKSIEEKEKQLDILSIQ 3281 Query: 938 SAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQ 997 + + ++K+L+ E + + Q+Q ++ +E NK + K +Q+ + Sbjct: 3282 NKVSNEKILD--LESQVNIMINKNEQIQNTYLALQTQYQVLE--NKYTQQ--HKKIQQLE 3335 Query: 998 TQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKL 1057 Q+ + + + L Q +II L K N + +S + + + L Sbjct: 3336 KQNDNTKSHLTISLQQAETQLSQTKMQIIELETK-NKRLIDDISRANHLKQLMKDQMEDL 3394 Query: 1058 E-NMEEEMQRVSKQL---LDSKQHNE--ELQILVREQDDQIKELKETKLTFEMNIPKTEG 1111 E N ++EM V ++ L++K E EL +++ +Q+++L+ K + ++ + Sbjct: 3395 EINFKKEMDEVREESIKDLNNKFEREKRELNFKIQKLGNQVRQLESDKDIMKQDLDAKQR 3454 Query: 1112 MIISSTIE 1119 + S T++ Sbjct: 3455 EVESITLQ 3462 Score = 86.2 bits (204), Expect = 7e-15 Identities = 175/892 (19%), Positives = 387/892 (43%), Gaps = 85/892 (9%) Query: 696 IKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKI------NHEEQSKIQT 749 I++L+++ + I N N + N + ++E+ + +K ++L +K N+ S+ Sbjct: 2375 IQNLQSNPQVINNGTNNIVYINQETQKRIEEQN-KKFNKLFSKDKGQHNPNNFSFSQKNQ 2433 Query: 750 QFGIDAKIQERDLYIE-NIESELSKYKSRICRLEES---IAVMEDR---RYSLER----- 797 Q +++IQ+++ + + N +++ SR R S IA +Y + R Sbjct: 2434 QSIQNSQIQQQNQFQQSNQQNQNQLESSRTLRSASSNPNIAANTQPIQLQYVISRNQLNQ 2493 Query: 798 -KADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQ 856 + Q + + + K ++ + L N ++ L + D ++KQ+ + E+K Q++N Sbjct: 2494 PQQQQQANIIPDNSKQINQQVNKNQILRNSISQLKNIDENIQKQI-KSNVEDKMQQEQNS 2552 Query: 857 ILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQT 916 L E +L + ++ ++++ N ++ + S + + ++ T Q Sbjct: 2553 SLHSETFSLNGTFDQTRE----ILKERNLQNMINTASKNFSKAQSHEQKIIELQTDRSQL 2608 Query: 917 L--IVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENL 974 L I K+ EI+DL+ + N + R K++ E + N Q + Q+Y+ E + Sbjct: 2609 LKMIATKQLEIDDLKQKNNQEAILIQRIDKLVEENEQLNF----QNQKLAQDYQQLNERV 2664 Query: 975 NMNVEE------LNKMNLELIDKHVQKQQTQSPDYTEQYI--NEINKLNALLKQKDEEII 1026 N N++ LN+ N L +K + Q+ + I NE N L ++++K E+I Sbjct: 2665 NQNLKYMKEYNLLNEENQSLCEKTEEYQELLDKLEIKITILSNENNTLLKMMEEKQEQIE 2724 Query: 1027 ALNQKINNAQVSYMSMVS--DYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQIL 1084 L Q+ S SM D K Q +LE E Q +K L + +E Q Sbjct: 2725 LLKQREEEHSQSQNSMTKFQDLLEKKNQLIKQLEKQLREAQEQNKVLNNEIIFQQE-QFT 2783 Query: 1085 VREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXL-K 1143 + ++ + + K T I E I+ + ++ ++ + Sbjct: 2784 EDKLNEAVSNIVSEKNTLIEQI-SAENSNFKIKIKSLLEENKSLQEKVAKQNAIEWYADQ 2842 Query: 1144 VQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKL 1203 ++ +E I+E +++++ N EL + KII L EL + ++ +Q K K Sbjct: 2843 LKTTKETIEENQMIKDRQLIENKELIQEMKKIIDLNKEQLELKENKILQLKQTYD-KEK- 2900 Query: 1204 EQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQRE-ADFQKTEHELRVQLS 1262 E + E ++ ++ E + + +++ E+ KQ + ++ AD+ + + ++ + Sbjct: 2901 EAILRETEHQINEKLEEIKAYTLEIEKFRDELVLTKKQLMEEKNRADYFQDQFKIYMGNQ 2960 Query: 1263 AFESKYEQ---LLDSVQSSTQEETNKIVTMEQVTSLQNK---LQDKEEHLRNLQEKYADV 1316 + K++Q ++++ + + + +KI + ++ L+NK + DK + + + + +V Sbjct: 2961 EHQ-KFQQEQIIMNTCLENKRSQQDKIHFLNEIEDLKNKNIAVTDKLDQMIAVNDNLTEV 3019 Query: 1317 INQI--EILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEEN 1374 + + EI IE +K+ + R + Q + + ++ + EE Sbjct: 3020 LKEKSQEIQELLIEKDKLLYE-----------------REQEQIQLERIQNNLHQLEEER 3062 Query: 1375 AQ-LKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRN-D 1432 LK++ N + ++ +L Q++ K+ E T+E Q+N + Sbjct: 3063 ENFLKETQDVYELKEKVSHQETNRYKQQIEDLKLQIQQKEFE----TNEQF----QKNLN 3114 Query: 1433 EFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELN 1492 + E +Q++++ + +I L Y+ + RLK+ E + T+ + +I IE N Sbjct: 3115 QLEQSQQEIIQLKDQINKLNYQISQIQSEDRLKIQERVHFDSTLLELQKINEDNQIEIAN 3174 Query: 1493 VKITESVSLNKQVAELNKALEEEVAKTN-EMQTALENQEIEIVTLNDEITNL 1543 +K + + L Q +L + L EE + + + + + +N E +I +L+ + L Sbjct: 3175 LK-DKLLKLENQRDKLQRQLSEEKEENDLKFRKSEQNYENQIASLDTKYKRL 3225 Score = 79.4 bits (187), Expect = 8e-13 Identities = 187/859 (21%), Positives = 369/859 (42%), Gaps = 124/859 (14%) Query: 235 EKQRLLKDIESKDVRISS----LEEANKLLEAARF--EISLEHSKLAQELEQXXXXXXXX 288 + Q+L +D + + R++ ++E N L E + E + E+ +L +LE Sbjct: 2649 QNQKLAQDYQQLNERVNQNLKYMKEYNLLNEENQSLCEKTEEYQELLDKLEIKITILSNE 2708 Query: 289 XXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTE----LTKKIELLEHLNCQIRQT--- 341 + ++ E E + EE+ S +MT+ L KK +L++ L Q+R+ Sbjct: 2709 NNTLLKMMEEKQE-QIELLKQREEEHSQSQNSMTKFQDLLEKKNQLIKQLEKQLREAQEQ 2767 Query: 342 NKELENKLATMG---TESK---AVSSPSKKGSPLISRKSGRNTASKMK-----SPWSQLS 390 NK L N++ TE K AVS+ + + LI + S N+ K+K L Sbjct: 2768 NKVLNNEIIFQQEQFTEDKLNEAVSNIVSEKNTLIEQISAENSNFKIKIKSLLEENKSLQ 2827 Query: 391 SETLNQD-----------TDKKINKNEIAKLEMVIQSLNKDLVD--KEYVISEKDTXXXX 437 + Q+ T + I +N++ K +I+ NK+L+ K+ + K+ Sbjct: 2828 EKVAKQNAIEWYADQLKTTKETIEENQMIKDRQLIE--NKELIQEMKKIIDLNKEQLELK 2885 Query: 438 XXXXXXGKDTLIAQLQ--LEHQQHMEGPSLIHVGTNTEDV----NEIAKVQEQLKQELN- 490 K T + + L +H L + T ++ +E+ ++QL +E N Sbjct: 2886 ENKILQLKQTYDKEKEAILRETEHQINEKLEEIKAYTLEIEKFRDELVLTKKQLMEEKNR 2945 Query: 491 -----DEIK--------------DVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKS 531 D+ K + + +E +S +++I LN+ D NKN+ Sbjct: 2946 ADYFQDQFKIYMGNQEHQKFQQEQIIMNTCLENKRSQQDKIHFLNEIEDLKNKNIAVTD- 3004 Query: 532 NHKLKLKQMQKTIDNFSKV-SDSNKEIVRLTEE----LHHLSQKVAELEEEKGNLQLHLV 586 KL QM DN ++V + ++EI L E L+ Q+ +LE + NL Sbjct: 3005 ----KLDQMIAVNDNLTEVLKEKSQEIQELLIEKDKLLYEREQEQIQLERIQNNLHQLEE 3060 Query: 587 DYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLAD 646 + ++ DVY+ ++ + R K Q DL +L I Q++++ E + Sbjct: 3061 ERENFLKETQDVYELKEKVSHQETNRYK------QQIEDL--KLQIQQKEFETNEQFQKN 3112 Query: 647 ISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLY-GTIKDLENDKED 705 ++QL+ Q EI + L++QI+ L+ ++ + LK+ + + T+ +L+ ED Sbjct: 3113 LNQLEQSQ--QEI--IQLKDQINKLNYQISQIQSE-DRLKIQERVHFDSTLLELQKINED 3167 Query: 706 IMNKLQNYIQENMDLT---DKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQ---E 759 ++ N + + L DKL++ +E+ E K EQ+ +D K + + Sbjct: 3168 NQIEIANLKDKLLKLENQRDKLQRQLSEEKEENDLKFRKSEQNYENQIASLDTKYKRLLD 3227 Query: 760 RDLYI----ENIESELSKYKSRICRLEESIAVME-DRRYSLERKADQLGSYLQEKQKAYS 814 Y+ E+ + EL+++K + ++ I + + S+E K QL L + K + Sbjct: 3228 EFKYLSESYEHKKQELNQFKEELPQIANKIKNEKIELTKSIEEKEKQL-DILSIQNKVSN 3286 Query: 815 EYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQ 874 E + + VN ++++ + ++ L ++ + + L+ K ++ Q L+ + + Sbjct: 3287 EKILDLESQVN---IMINKNEQIQNTYLALQTQYQVLENKYTQQHKKIQQLEKQNDNTKS 3343 Query: 875 HYNALVEKANRTDLAESEST--KYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEF 932 H +++A T L++++ + +T+ + L ++ R H Q + K ++EDLEI F Sbjct: 3344 HLTISLQQAE-TQLSQTKMQIIELETKNKRLIDDISRANHLKQLM----KDQMEDLEINF 3398 Query: 933 NTQI----ESAIRD--------KKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEE 980 ++ E +I+D K+ LN K +K V QLE+ K +++ VE Sbjct: 3399 KKEMDEVREESIKDLNNKFEREKRELNFKIQKLGNQVRQLESDKDIMKQDLDAKQREVES 3458 Query: 981 LNKMNLELIDKHVQKQQTQ 999 + + ++ Q Q Sbjct: 3459 ITLQLQRVAEREKNLYQKQ 3477 Score = 69.7 bits (163), Expect = 6e-10 Identities = 145/730 (19%), Positives = 297/730 (40%), Gaps = 56/730 (7%) Query: 849 KELQKKNQILLEENQNLQISLSDMQQHY--NALVEKANRTDLAESESTKYQTQLRDLESN 906 +++Q K Q L N+NL + +Q H N +A ++ + Q + + +N Sbjct: 2334 QQVQAKLQPNLANNKNLPYQMV-IQPHIQQNQFSNQAQNIQPIQNLQSNPQV-INNGTNN 2391 Query: 907 LKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQE 966 + I E Q I ++ K+ L F+ + ++K +++I+ +Q++ Q Q Sbjct: 2392 IVYINQETQKRIEEQNKKFNKL---FSKDKGQHNPNNFSFSQKNQQSIQN-SQIQQQNQF 2447 Query: 967 YKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEII 1026 ++N +N N +E + + ++ TQ QY+ N+LN +Q+ II Sbjct: 2448 QQSNQQNQNQ-LESSRTLRSASSNPNIAAN-TQPIQL--QYVISRNQLNQPQQQQQANII 2503 Query: 1027 ALNQKINNAQVSYMSMVSDYESKLAQFTTKLE-NMEEEMQRVSKQLLDSKQHNEELQILV 1085 N K N QV+ ++ + S+L ++ ++ ++ +Q +S H+E + Sbjct: 2504 PDNSKQINQQVNKNQILRNSISQLKNIDENIQKQIKSNVEDKMQQEQNSSLHSETFSL-- 2561 Query: 1086 REQDDQIKE-LKETKLTFEMNIPK---TEGMIISSTIEPMSDDANNVDXXXXXXXXXXXX 1141 DQ +E LKE L +N ++ I + D + + Sbjct: 2562 NGTFDQTREILKERNLQNMINTASKNFSKAQSHEQKIIELQTDRSQLLKMIATKQLEIDD 2621 Query: 1142 LKVQEEEE--FIQERSVLQEQSAKLNTELQECYTKIIQL-ETLNTELTGHDVVNQEQINQ 1198 LK + +E IQ L E++ +LN + Q+ QL E +N L N +N+ Sbjct: 2622 LKQKNNQEAILIQRIDKLVEENEQLNFQNQKLAQDYQQLNERVNQNLKYMKEYN--LLNE 2679 Query: 1199 LKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQH---LAQREADFQKTEH 1255 L + E LL + E++ +I S + ++ E ++ L QRE + ++++ Sbjct: 2680 ENQSLCEKTEEYQELLDKL-EIKITILSNENNTLLKMMEEKQEQIELLKQREEEHSQSQN 2738 Query: 1256 ELRVQLSAFESKYEQLLDSVQSSTQE--ETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKY 1313 + E K QL+ ++ +E E NK++ E + + +DK L E Sbjct: 2739 SMTKFQDLLEKK-NQLIKQLEKQLREAQEQNKVLNNEIIFQQEQFTEDK------LNEAV 2791 Query: 1314 ADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQ-SYKQMQEQSILNINE 1372 ++++++ L +I E F + +N + Q ++ E Sbjct: 2792 SNIVSEKNTLIEQISAENSNFKIKIKSLLEENKSLQEKVAKQNAIEWYADQLKTTKETIE 2851 Query: 1373 ENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLT--QR 1430 EN +K ++ D + LEL L+ + Y K E + T Q Sbjct: 2852 ENQMIKDRQLIENKELIQEMKKIIDLNKEQLELKENKILQLKQTYDKEKEAILRETEHQI 2911 Query: 1431 NDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEE 1490 N++ E ++ +E EK EL + + ++ E N + Q + ++ + + Sbjct: 2912 NEKLEEIKAYTLEIEK--------FRDELVLTKKQLMEEKNRADYFQDQF---KIYMGNQ 2960 Query: 1491 LNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEI----TNLQNM 1546 + K + + E ++ ++++ NE++ L+N+ I + D++ NL + Sbjct: 2961 EHQKFQQEQIIMNTCLENKRSQQDKIHFLNEIED-LKNKNIAVTDKLDQMIAVNDNLTEV 3019 Query: 1547 VRASSSKIQK 1556 ++ S +IQ+ Sbjct: 3020 LKEKSQEIQE 3029 Score = 61.7 bits (143), Expect = 2e-07 Identities = 144/740 (19%), Positives = 309/740 (41%), Gaps = 68/740 (9%) Query: 151 IKEKDNALSVLQVKMKIMETTILDLQE-----KINEK-DQIIEAKNKATTXXXXXXXXXX 204 IK+ + L Q + K++ I+ QE K+NE I+ KN Sbjct: 2754 IKQLEKQLREAQEQNKVLNNEIIFQQEQFTEDKLNEAVSNIVSEKNTLIEQISAENSNFK 2813 Query: 205 XXXXXXXEDTKQQMTKM-QENFIAMEAEWKDEKQRLLKDI--ESKDVRISSLEEANKLLE 261 E+ K K+ ++N I EW ++ + K+ E++ ++ L E +L++ Sbjct: 2814 IKIKSLLEENKSLQEKVAKQNAI----EWYADQLKTTKETIEENQMIKDRQLIENKELIQ 2869 Query: 262 AARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANM 321 + I L +L + + + +++ E EK E + +LEI Sbjct: 2870 EMKKIIDLNKEQLELKENKILQLKQTYDKEKEAILRET-EHQINEKLEEIKAYTLEIEKF 2928 Query: 322 TE---LTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNT 378 + LTKK +L+E N R + + K+ E + + + K + Sbjct: 2929 RDELVLTKK-QLMEEKN---RADYFQDQFKIYMGNQEHQKFQQEQIIMNTCLENKRSQQD 2984 Query: 379 ASKMKSPWSQLSSETLNQDTDK-----KINKNEIAKLEMVIQSLNKDLVDKEYVISEKDT 433 + L ++ + TDK +N N L+ Q + + L++K+ ++ E++ Sbjct: 2985 KIHFLNEIEDLKNKNIAV-TDKLDQMIAVNDNLTEVLKEKSQEIQELLIEKDKLLYEREQ 3043 Query: 434 XXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHV---GTNTEDVNEIAKVQEQLKQELN 490 + QL+ E + ++ ++ + ++ N + E LK ++ Sbjct: 3044 EQIQLERIQNN----LHQLEEERENFLKETQDVYELKEKVSHQETNRYKQQIEDLKLQIQ 3099 Query: 491 DEIKDVN--VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQ---MQKTID 545 + + N + + +L+ ++++I QL D+I+ N + +++S +LK+++ T+ Sbjct: 3100 QKEFETNEQFQKNLNQLEQSQQEIIQLKDQINKLNYQISQIQSEDRLKIQERVHFDSTLL 3159 Query: 546 NFSKVSDSNK-EIVRLTEELHHLSQKVAEL------EEEKGNLQLHLVDYDSGRMIES-- 596 K+++ N+ EI L ++L L + +L E+E+ +L+ + + I S Sbjct: 3160 ELQKINEDNQIEIANLKDKLLKLENQRDKLQRQLSEEKEENDLKFRKSEQNYENQIASLD 3219 Query: 597 DVYKKMI-EMENLAETRLKAISLLESQKFDLVQELHILQQKYDE----VEDKLADISQLQ 651 YK+++ E + L+E+ L K +L Q + ++ + E +E+K + L Sbjct: 3220 TKYKRLLDEFKYLSESYEHKKQELNQFKEELPQIANKIKNEKIELTKSIEEKEKQLDILS 3279 Query: 652 SDQVCSEIKSVHLEEQIDALSASKKE-----LALVIENLKLDKE--QLYGTIKDLENDKE 704 S K + LE Q++ + ++ LAL + L+ + Q + I+ LE + Sbjct: 3280 IQNKVSNEKILDLESQVNIMINKNEQIQNTYLALQTQYQVLENKYTQQHKKIQQLEKQND 3339 Query: 705 DIMNKLQNYIQE-NMDLTD-KLEKMSAE----KISELLAKINHEEQ-SKIQTQ-FGIDAK 756 + + L +Q+ L+ K++ + E ++ + +++ NH +Q K Q + I+ K Sbjct: 3340 NTKSHLTISLQQAETQLSQTKMQIIELETKNKRLIDDISRANHLKQLMKDQMEDLEINFK 3399 Query: 757 IQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEY 816 + ++ E+I+ +K++ L I + ++ LE D + L KQ+ Sbjct: 3400 KEMDEVREESIKDLNNKFEREKRELNFKIQKLGNQVRQLESDKDIMKQDLDAKQREVESI 3459 Query: 817 TIQEDELVNRLAVLMDHDRV 836 T+Q + R L R+ Sbjct: 3460 TLQLQRVAEREKNLYQKQRL 3479 >UniRef50_UPI00006CCC54 Cluster: hypothetical protein TTHERM_00335640; n=1; Tetrahymena thermophila SB210|Rep: hypothetical protein TTHERM_00335640 - Tetrahymena thermophila SB210 Length = 1512 Score = 128 bits (309), Expect = 1e-27 Identities = 201/1019 (19%), Positives = 451/1019 (44%), Gaps = 85/1019 (8%) Query: 308 TEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELEN---KLATMGTESKAVSSPSK 364 T+I + ++I N+ + K+ N +++ +N +L+ +L+ + TE++A+ Sbjct: 344 TQINDVQQVKIKNLEQALDKVN---EENIKLQSSNLDLDQVKTELSVIKTENEALRQSQT 400 Query: 365 KGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDK 424 GS ++++ ++ + + K+N + I++LE I + K+L +K Sbjct: 401 SGSESLTQEIKLLEQQYLQEKDKNHHLVAAHSEEILKLN-HHISELEDQIVHIQKELNEK 459 Query: 425 EYVISEKDTXXXXXXXXXXGKDTLIAQL-QLEHQQHMEGPSLIHVGT-NTEDVNEIAKVQ 482 + + K+T+ L + E E ++H+ + N +V+ + + Sbjct: 460 SIQVQQLQKEKEIILVE---KNTISQSLVEKETIIEKEKKEIVHISSVNESEVHSLREQI 516 Query: 483 EQLKQE--LNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQM 540 +L+ E LN E + + LIE LK I + + ++ + +++V+ ++K+ + Sbjct: 517 SKLQSEIRLNSEGQQNDFTALIEALK---RDIEEKDQQLKQLREFVMEVQHAGQIKVLER 573 Query: 541 QKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYK 600 ++ + K+ +S KE EL LS K+ ++ EK V + G + ES Sbjct: 574 EQQLLEKDKIIESQKE------ELMLLSSKLEQVIREK----TFTVSGEIGHVTESVRID 623 Query: 601 KMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDE--VEDKLADISQLQSDQVCSE 658 + + ET +K VQE+ I ++ +E VE+ D+ Q+ + E Sbjct: 624 VKSQNKERQETEVK----------QQVQEIPIEGEEEEEAGVEEVEFDMEVKQAKETRQE 673 Query: 659 IKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLEN---DKEDIMN-KLQNYI 714 +Q +LS E V +NL +K+ L + +L D E N K+ Y Sbjct: 674 GDKQGFFDQASSLSKELMENKQVQDNLLKEKDGLSKKVTELNVKYLDAEKQNNEKIAQYQ 733 Query: 715 QENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAK-IQERDLYIENIESELSK 773 ++ +L +++K+ + + EL +I +++ Q Q DAK + E + + ++++ Sbjct: 734 KQEAELKQQIQKLQ-QNVDELTKQIQSQKE---QLQQDADAKLVNETNKIKQGHQAKVIY 789 Query: 774 YKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDH 833 + I L+E + E++ S +R + L S + +++ ++ EL N L + Sbjct: 790 LNAEIAALKEKLN--EEKTQSEQRVSQVLQSQNSSSSELITKHELRVTELQNNFN-LQRN 846 Query: 834 DRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLS-DMQQHYNALVEKANRTDLAESE 892 D +E ++++++H+ L++K L +E N + ++ ++ + ++L E+A +L +E Sbjct: 847 D--LETKIVDLQHQLAALEQK---LRDEKSNHEALINQNIASNKSSLDEQARGYELKLAE 901 Query: 893 STK-YQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQI---ESAIRDKKVLNE 948 K Y+ ++ ++ S ++ + E + + KK+I +L+ + + E K L + Sbjct: 902 QQKSYELKITEINSKHQQASQEVE---INYKKQITELQAQSQLNLKLFEERETTTKQLEQ 958 Query: 949 KYEKNIEYVTQLE-AQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQY 1007 + + I+ + +++ KN +++ NK + + +Q + Q + + + Sbjct: 959 NHSQAIQNIKDTHLSEINNLKNQFSADQAKLQQENKAVITQLKAQIQNLEIQINELNQNH 1018 Query: 1008 INEINKLNALLKQKDEEI-IALNQKINNAQVSYMSMVSDY-ESKLAQFTTKLENMEEEMQ 1065 +I LN + K ++ + Q I+ + S+ + +S E+ + + E ++++ Sbjct: 1019 SIQIQNLNKDHQAKLTQVEVQYKQTISTIEESHKTYISSIQENHKKEISLAEEASKKQLN 1078 Query: 1066 RVSKQLLDS--KQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSD 1123 +Q L++ Q+ + + L E QI++L++ N+ K I TI+ + Sbjct: 1079 ASEQQKLETIENQYKQRINNLESEHKLQIEQLEKQHTQKVSNLEKDFQSKIDETIKSYNI 1138 Query: 1124 DANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVL----QEQSAKLNTELQECYTKIIQLE 1179 ++ + + E+EE + S Q++ A+L E+ E KI E Sbjct: 1139 KIQEIEKNYSQKIA----IVISEKEELSAQNSAASKGQQDKEAQLQKEISELKLKI---E 1191 Query: 1180 TLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRG--FEIAE 1237 TL + +E+ N L+ ++Q++ + N +S + ++SS SS+ G + Sbjct: 1192 TLVNNHQKEIIKQEEKYNLLRQTVQQISQNSQN-VSVTSNIQSSSSSSTVNNGDYLVLQH 1250 Query: 1238 LWKQHLAQREADFQKTEHELRVQ--LSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTS 1294 + Q + + + +K + E R+ L K EQ ++++ + K T E T+ Sbjct: 1251 DYNQLIEVNKENLKKIQEERRLYGILQDDYIKLEQQFTTLKNEKKNSDKKSKTAESNTA 1309 Score = 101 bits (241), Expect = 2e-19 Identities = 179/874 (20%), Positives = 387/874 (44%), Gaps = 87/874 (9%) Query: 496 VNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLK-QMQKTIDNF-SKVSDS 553 V VK ++ L +E++ Q E K++ + + K +++ + +KT+D+ + ++S Sbjct: 266 VEVKAQMKYLSHVKEEMLQKQQEYQ---KDISGLLTGMKREMEAEFEKTLDHVHNSQNES 322 Query: 554 N-------KEIVRLTEELHHLSQKVAELEEEK-GNLQ--LHLVDYDSGRMIESDVYKKMI 603 N KE+ LTE+L +S ++ ++++ K NL+ L V+ ++ ++ S++ + Sbjct: 323 NQKSLVLQKEVETLTEKLF-MSTQINDVQQVKIKNLEQALDKVNEENIKLQSSNLDLDQV 381 Query: 604 EME-NLAETRLKAISLLESQKFD-LVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKS 661 + E ++ +T +A+ ++ + L QE+ +L+Q+Y + +DK + S+++ Sbjct: 382 KTELSVIKTENEALRQSQTSGSESLTQEIKLLEQQYLQEKDKNHHLVAAHSEEILKLNHH 441 Query: 662 V-HLEEQIDALSASKKELALVIENLKLDKEQLY---GTIKDLENDKEDIMNKLQNYIQEN 717 + LE+QI + E ++ ++ L+ +KE + TI +KE I+ K + I Sbjct: 442 ISELEDQIVHIQKELNEKSIQVQQLQKEKEIILVEKNTISQSLVEKETIIEKEKKEIVHI 501 Query: 718 MDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSR 777 + + E+IS+L ++I + + Q F + +RD IE + +L + + Sbjct: 502 SSVNESEVHSLREQISKLQSEIRLNSEGQ-QNDFTALIEALKRD--IEEKDQQLKQLREF 558 Query: 778 ICRLEES--IAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDR 835 + ++ + I V+E + LE+ D++ +E+ S +++ V + Sbjct: 559 VMEVQHAGQIKVLEREQQLLEK--DKIIESQKEELMLLSS-KLEQVIREKTFTVSGEIGH 615 Query: 836 VVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKAN-RTDLAESEST 894 V E ++++ +NKE Q+ E Q +Q + ++ A VE+ ++ +++ T Sbjct: 616 VTESVRIDVKSQNKERQET-----EVKQQVQEIPIEGEEEEEAGVEEVEFDMEVKQAKET 670 Query: 895 KYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEK-N 953 + + + ++ E + + K+++D ++ + + + V EK N Sbjct: 671 RQEGDKQGFFDQASSLSKE-----LMENKQVQDNLLKEKDGLSKKVTELNVKYLDAEKQN 725 Query: 954 IEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINK 1013 E + Q + Q E K I+ L NV+EL K QK+Q Q D + +NE NK Sbjct: 726 NEKIAQYQKQEAELKQQIQKLQQNVDELTKQIQS------QKEQLQQ-DADAKLVNETNK 778 Query: 1014 LNALLKQK----DEEIIALNQKINNAQVSYMSMVSDY----ESKLAQFTTKLENMEEEMQ 1065 + + K + EI AL +K+N + VS S ++ TK E E+Q Sbjct: 779 IKQGHQAKVIYLNAEIAALKEKLNEEKTQSEQRVSQVLQSQNSSSSELITKHELRVTELQ 838 Query: 1066 R-VSKQLLDSKQHNEELQILVREQDDQIKELKET-KLTFEMNIPKTEGMIISSTIE---P 1120 + Q D + +LQ + + ++++ K + NI + + Sbjct: 839 NNFNLQRNDLETKIVDLQHQLAALEQKLRDEKSNHEALINQNIASNKSSLDEQARGYELK 898 Query: 1121 MSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTEL-QECYTKIIQLE 1179 +++ + + + E + ++ + LQ QS +LN +L +E T QLE Sbjct: 899 LAEQQKSYELKITEINSKHQQASQEVEINYKKQITELQAQS-QLNLKLFEERETTTKQLE 957 Query: 1180 TLNTE-LTGHDVVNQEQINQLKSKL--EQLNTENDN------LLSTVAELRSSISSAVDQ 1230 +++ + + +IN LK++ +Q + +N L + + L I+ Sbjct: 958 QNHSQAIQNIKDTHLSEINNLKNQFSADQAKLQQENKAVITQLKAQIQNLEIQINELNQN 1017 Query: 1231 RGFEIAELWKQH---LAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIV 1287 +I L K H L Q E +++T +S E ++ + S+Q + ++E + Sbjct: 1018 HSIQIQNLNKDHQAKLTQVEVQYKQT-------ISTIEESHKTYISSIQENHKKE----I 1066 Query: 1288 TMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIE 1321 ++ + S + +++ L ++ +Y IN +E Sbjct: 1067 SLAEEASKKQLNASEQQKLETIENQYKQRINNLE 1100 Score = 85.0 bits (201), Expect = 2e-14 Identities = 151/763 (19%), Positives = 313/763 (41%), Gaps = 61/763 (7%) Query: 213 DTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHS 272 D ++Q + + EAE K + Q+L ++++ +I S +E +L + A ++ E + Sbjct: 720 DAEKQNNEKIAQYQKQEAELKQQIQKLQQNVDELTKQIQSQKE--QLQQDADAKLVNETN 777 Query: 273 KLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEI----ANMTELTKKI 328 K ++Q K+ + EEKT+ E++ S + ++ +EL K Sbjct: 778 K----IKQGHQAKVIYLNAEIAALKEKLN---EEKTQSEQRVSQVLQSQNSSSSELITKH 830 Query: 329 EL-LEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWS 387 EL + L +LE K+ + + A+ + +N AS S Sbjct: 831 ELRVTELQNNFNLQRNDLETKIVDLQHQLAALEQKLRDEKSNHEALINQNIASNKSSLDE 890 Query: 388 QLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDL-VDKEYVISEKDTXXXXXXXXXXGKD 446 Q L +K + +I ++ Q ++++ ++ + I+E ++ Sbjct: 891 QARGYELKLAEQQKSYELKITEINSKHQQASQEVEINYKKQITELQAQSQLNLKLFEERE 950 Query: 447 TLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLK 506 T QL+ H Q ++ H+ N+ + Q +L+QE N + + L +++ Sbjct: 951 TTTKQLEQNHSQAIQNIKDTHLSEINNLKNQFSADQAKLQQE-NKAV----ITQLKAQIQ 1005 Query: 507 SAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQ-KTIDNFSKVSDSNKEIVRLTEELH 565 + E QI +LN +N+ K +H+ KL Q++ + S + +S+K + +E H Sbjct: 1006 NLEIQINELNQNHSIQIQNLNK---DHQAKLTQVEVQYKQTISTIEESHKTYISSIQENH 1062 Query: 566 HLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFD 625 +K L EE QL+ + IE+ YK+ I NL I LE Q Sbjct: 1063 ---KKEISLAEEASKKQLNASEQQKLETIENQ-YKQRI--NNLESEHKLQIEQLEKQHTQ 1116 Query: 626 LVQELH-ILQQKYDEV----EDKLADISQLQSDQVCSEI-KSVHLEEQIDALSASKK--- 676 V L Q K DE K+ +I + S ++ I + L Q A S ++ Sbjct: 1117 KVSNLEKDFQSKIDETIKSYNIKIQEIEKNYSQKIAIVISEKEELSAQNSAASKGQQDKE 1176 Query: 677 -ELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISEL 735 +L I LKL E L + +E+ N L+ +Q+ + + S + S Sbjct: 1177 AQLQKEISELKLKIETLVNNHQKEIIKQEEKYNLLRQTVQQISQNSQNVSVTSNIQSSSS 1236 Query: 736 LAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKY---KSRICRLEESIAVMEDRR 792 + +N+ + +Q + ++ + +L + I+ E Y + +LE+ +++ + Sbjct: 1237 SSTVNNGDYLVLQHDYNQLIEVNKENL--KKIQEERRLYGILQDDYIKLEQQFTTLKNEK 1294 Query: 793 YSLERK---------ADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLE 843 + ++K A Q K KAY E + + + + + + + + L+ Sbjct: 1295 KNSDKKSKTAESNTAATTTSGASQLKNKAYFEVDQRVSKELELTVLKLKEENAIIRDQLK 1354 Query: 844 IEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTK----YQTQ 899 E+E+K + Q + E + I L ++ A+ ++ D ++ + Sbjct: 1355 KEYEDKIYSLEKQAI--EYEKKMIELEQVKVELKAMKDEKEEADWEKARKNNGNKGASKE 1412 Query: 900 LRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRD 942 + ++ L++ E Q ++ +K +EI L+ ++ ++E +++ Sbjct: 1413 EQAKKTGLEKEKEELQKVLEKKNEEIRKLKNDYK-KLEKQLKN 1454 Score = 84.6 bits (200), Expect = 2e-14 Identities = 170/795 (21%), Positives = 343/795 (43%), Gaps = 98/795 (12%) Query: 793 YSLERKADQ--LGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKE 850 Y +E KA L +E + EY L+ + M+ + EK L + + E Sbjct: 264 YRVEVKAQMKYLSHVKEEMLQKQQEYQKDISGLLTGMKREMEAE--FEKTLDHVHNSQNE 321 Query: 851 LQKKNQILLEENQNL------QISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLE 904 +K+ +L +E + L ++D+QQ +E+A D E+ K Q+ DL+ Sbjct: 322 SNQKSLVLQKEVETLTEKLFMSTQINDVQQVKIKNLEQA--LDKVNEENIKLQSSNLDLD 379 Query: 905 ---SNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKK-------VLNEKYEKNI 954 + L I E++ L + E L E + +++K +E+ K Sbjct: 380 QVKTELSVIKTENEALRQSQTSGSESLTQEIKLLEQQYLQEKDKNHHLVAAHSEEILKLN 439 Query: 955 EYVTQLEAQLQEYKNNIENLNMNVEELNK-MNLELIDKHVQKQQ-TQSPDYTEQYINEIN 1012 ++++LE Q+ + + ++ V++L K + L++K+ Q + E+ EI Sbjct: 440 HHISELEDQIVHIQKELNEKSIQVQQLQKEKEIILVEKNTISQSLVEKETIIEKEKKEIV 499 Query: 1013 KLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLL 1072 ++++ + E+ +L ++I+ Q S + + S E + FT +E ++ +++ +QL Sbjct: 500 HISSV---NESEVHSLREQISKLQ-SEIRLNS--EGQQNDFTALIEALKRDIEEKDQQLK 553 Query: 1073 DSKQHNEELQ----ILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNV 1128 ++ E+Q I V E++ Q+ L++ K+ + K E M++SS +E + + Sbjct: 554 QLREFVMEVQHAGQIKVLEREQQL--LEKDKI---IESQKEELMLLSSKLEQVIREKTFT 608 Query: 1129 DXXXXXXXXXXXXLKVQEEEEFIQERSVLQE-QSAKLN-TELQECYTKIIQ--LETLNTE 1184 + V+ + + QE V Q+ Q + E +E + ++ +E + Sbjct: 609 VSGEIGHVTESVRIDVKSQNKERQETEVKQQVQEIPIEGEEEEEAGVEEVEFDMEVKQAK 668 Query: 1185 LTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLA 1244 T + Q +Q S ++L EN + + + + +S V + + + KQ+ Sbjct: 669 ETRQEGDKQGFFDQASSLSKEL-MENKQVQDNLLKEKDGLSKKVTELNVKYLDAEKQN-N 726 Query: 1245 QREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEE 1304 ++ A +QK E EL+ Q+ + ++L +QS Q+E + ++ + NK+ K+ Sbjct: 727 EKIAQYQKQEAELKQQIQKLQQNVDELTKQIQS--QKEQLQQDADAKLVNETNKI--KQG 782 Query: 1305 HLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQE 1364 H Q K + +I L+ ++ +EK L+++N S ++ Sbjct: 783 H----QAKVIYLNAEIAALKEKLNEEKTQSEQRVSQV----------LQSQNSSSSELIT 828 Query: 1365 QSILNINE--ENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHE 1422 + L + E N L++ ND E K+++L HQL + ++ + Sbjct: 829 KHELRVTELQNNFNLQR----------------NDLETKIVDLQHQLAALEQKLRDEKSN 872 Query: 1423 YTITLTQR-NDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESE 1481 + + Q ++ +Q YE ++ + +K EL I + N+ H + Q E E Sbjct: 873 HEALINQNIASNKSSLDEQARGYELKLAE--QQKSYELKITEI----NSKHQQASQ-EVE 925 Query: 1482 IERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEIT 1541 I K I EL + ++ L ++ K LE+ N Q A++N I+ L+ EI Sbjct: 926 INYKKQITELQAQSQLNLKLFEERETTTKQLEQ-----NHSQ-AIQN--IKDTHLS-EIN 976 Query: 1542 NLQNMVRASSSKIQK 1556 NL+N A +K+Q+ Sbjct: 977 NLKNQFSADQAKLQQ 991 Score = 76.6 bits (180), Expect = 5e-12 Identities = 195/1015 (19%), Positives = 425/1015 (41%), Gaps = 101/1015 (9%) Query: 147 LSNTIKEKDNALSVL-QVKMKIM---ETTILDLQEKINEKDQIIEAKNKATTXXXXXXXX 202 L I+EKD L L + M++ + +L+ ++++ EKD+IIE++ + Sbjct: 541 LKRDIEEKDQQLKQLREFVMEVQHAGQIKVLEREQQLLEKDKIIESQKEELMLLSSKLEQ 600 Query: 203 XXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEA 262 +T+ I ++++ K+ ++ +K + +++ I EE +E Sbjct: 601 VIREKTFTVSGEIGHVTESVR--IDVKSQNKERQETEVKQ-QVQEIPIEGEEEEEAGVEE 657 Query: 263 ARFEISLEHSK-LAQELEQXXXXXXXXXXXXXXLAKQSIEPSC-EEKTEIEEKGS-LEIA 319 F++ ++ +K QE ++ + + ++ + +EK + +K + L + Sbjct: 658 VEFDMEVKQAKETRQEGDKQGFFDQASSLSKELMENKQVQDNLLKEKDGLSKKVTELNVK 717 Query: 320 NMT---ELTKKIELLEHLNCQIRQTNKELENKL--ATMGTESKAVSSPSKKGSPLISRKS 374 + + +KI + +++Q ++L+ + T +S+ + L++ + Sbjct: 718 YLDAEKQNNEKIAQYQKQEAELKQQIQKLQQNVDELTKQIQSQKEQLQQDADAKLVNETN 777 Query: 375 GRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTX 434 + K + L + +++ ++E ++ V+QS N E + + Sbjct: 778 KIKQGHQAKVIYLNAEIAALKEKLNEEKTQSE-QRVSQVLQSQNSS--SSELITKHELRV 834 Query: 435 XXXXXXXXXGKDTLIAQL-QLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEI 493 ++ L ++ L+HQ L +N E + I + K L+++ Sbjct: 835 TELQNNFNLQRNDLETKIVDLQHQLAALEQKLRDEKSNHEAL--INQNIASNKSSLDEQA 892 Query: 494 KDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDS 553 + +K L E+ KS E +IT++N + A++ +V+ N+K ++ ++Q K+ + Sbjct: 893 RGYELK-LAEQQKSYELKITEINSKHQQASQ---EVEINYKKQITELQAQSQLNLKLFEE 948 Query: 554 NKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRL 613 + + E+ H SQ + +++ HL + ++ + S K+ + T+L Sbjct: 949 RETTTKQLEQNH--SQAIQNIKDT------HLSEINNLKNQFSADQAKLQQENKAVITQL 1000 Query: 614 KA-ISLLESQKFDLVQELHI-LQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDAL 671 KA I LE Q +L Q I +Q + + KL + ++Q Q S I+ H Sbjct: 1001 KAQIQNLEIQINELNQNHSIQIQNLNKDHQAKLTQV-EVQYKQTISTIEESHKTYISSIQ 1059 Query: 672 SASKKELALVIENLKLDKEQLYGTIKD-LENDKEDIMNKLQNYIQENMDLTDKLEKMSAE 730 KKE++L E K+QL + + LE + ++ N E+ ++LEK + Sbjct: 1060 ENHKKEISLAEE---ASKKQLNASEQQKLETIENQYKQRINNLESEHKLQIEQLEKQHTQ 1116 Query: 731 KISELLAKINHEEQSKI-QTQFGIDAKIQERDL-YIENIESELSKYKSRICRLEESIAVM 788 K+S L + QSKI +T + KIQE + Y + I +S+ + + + Sbjct: 1117 KVSNL----EKDFQSKIDETIKSYNIKIQEIEKNYSQKIAIVISEKEELSAQNSAASKGQ 1172 Query: 789 EDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDH--------------- 833 +D+ L+++ +L ++ + + I+++E N L + Sbjct: 1173 QDKEAQLQKEISELKLKIETLVNNHQKEIIKQEEKYNLLRQTVQQISQNSQNVSVTSNIQ 1232 Query: 834 -----DRVVEKQLLEIEHENKEL---QKKNQILLEENQNLQISLSD----MQQHYNALV- 880 V L ++H+ +L K+N ++E + L L D ++Q + L Sbjct: 1233 SSSSSSTVNNGDYLVLQHDYNQLIEVNKENLKKIQEERRLYGILQDDYIKLEQQFTTLKN 1292 Query: 881 EKAN---RTDLAESES----TKYQTQLRD---LESNLKRITHEHQTLIVQKKKEIEDLEI 930 EK N ++ AES + T +QL++ E + +R++ E + +++ K+E + Sbjct: 1293 EKKNSDKKSKTAESNTAATTTSGASQLKNKAYFEVD-QRVSKELELTVLKLKEENAIIRD 1351 Query: 931 EFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELID 990 + + E I + +YEK + + Q++ +L+ K+ E + N N Sbjct: 1352 QLKKEYEDKIYSLEKQAIEYEKKMIELEQVKVELKAMKDEKEEADWEKARKNNGN----- 1406 Query: 991 KHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKL 1050 K K++ E+ E+ K +L++K+EEI +K+ N + + ++K Sbjct: 1407 KGASKEEQAKKTGLEKEKEELQK---VLEKKNEEI----RKLKNDYKKLEKQLKNLQAKS 1459 Query: 1051 AQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMN 1105 Q T +E + +++ K + +I DD K K + + +++N Sbjct: 1460 PQVTPAPATVESQPTLNTEEAETKKGKKKGYKI----DDDLQKIFKLSDIIYQIN 1510 Score = 58.8 bits (136), Expect = 1e-06 Identities = 123/662 (18%), Positives = 277/662 (41%), Gaps = 46/662 (6%) Query: 954 IEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELID---KHVQKQQTQSPDYTEQYINE 1010 I Y +++AQ++ + E + +E K L+ + ++ + ++ D+ NE Sbjct: 262 INYRVEVKAQMKYLSHVKEEMLQKQQEYQKDISGLLTGMKREMEAEFEKTLDHVHNSQNE 321 Query: 1011 INKLNALLKQKDE---EIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRV 1067 N+ + +L+++ E E + ++ +IN+ Q + + K+ + KL++ ++ +V Sbjct: 322 SNQKSLVLQKEVETLTEKLFMSTQINDVQQVKIKNLEQALDKVNEENIKLQSSNLDLDQV 381 Query: 1068 SKQLLDSKQHNEEL-QILVREQDDQIKELKETKLTFEMNIPKTEGMI---------ISST 1117 +L K NE L Q + +E+K + + K ++ ++ Sbjct: 382 KTELSVIKTENEALRQSQTSGSESLTQEIKLLEQQYLQEKDKNHHLVAAHSEEILKLNHH 441 Query: 1118 IEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQ 1177 I + D ++ L+ +E+E + E++ + + + T +++ +I+ Sbjct: 442 ISELEDQIVHIQKELNEKSIQVQQLQ-KEKEIILVEKNTISQSLVEKETIIEKEKKEIVH 500 Query: 1178 LETLNTELTGHDVVNQEQINQLKSKLEQLNTE--NDNLLSTVAELRSSISSAVDQRGFEI 1235 + ++N E H + +EQI++L+S++ +LN+E ++ + + L+ I DQ+ ++ Sbjct: 501 ISSVN-ESEVHSL--REQISKLQSEI-RLNSEGQQNDFTALIEALKRDIEEK-DQQLKQL 555 Query: 1236 AELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSL 1295 E + + + E +L + ES+ E+L+ Q K T+ Sbjct: 556 REFVMEVQHAGQIKVLEREQQLLEKDKIIESQKEELMLLSSKLEQVIREKTFTVSGEIGH 615 Query: 1296 QNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTE 1355 + + +N + + +V Q++ + E E+E+ A T Sbjct: 616 VTESVRIDVKSQNKERQETEVKQQVQEIPIEGEEEEEAGVEEVEFDMEVKQAK----ETR 671 Query: 1356 NQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSE 1415 + KQ ++++E + K+ +V + K L+ Q K ++ Sbjct: 672 QEGDKQGFFDQASSLSKELMENKQVQDNLLKEKDGLSKKVTELNVKYLDAEKQNNEKIAQ 731 Query: 1416 IYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYET 1475 YQK Q+ +NV + + + + E L + +++L K+ + + + Sbjct: 732 -YQKQEAELKQQIQKLQ--QNVDELTKQIQSQKEQLQQDADAKLVNETNKI-KQGHQAKV 787 Query: 1476 MQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQ-TALENQ-EIEI 1533 + +EI +K E+LN + T+S QV + + E+ +E++ T L+N ++ Sbjct: 788 IYLNAEIAALK--EKLNEEKTQSEQRVSQVLQSQNSSSSELITKHELRVTELQNNFNLQR 845 Query: 1534 VTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTM--NKELLDAVPRA-ELD 1590 L +I +LQ+ + A K++ D K + ++ + NK LD R EL Sbjct: 846 NDLETKIVDLQHQLAALEQKLR-------DEKSNHEALINQNIASNKSSLDEQARGYELK 898 Query: 1591 LA 1592 LA Sbjct: 899 LA 900 >UniRef50_A4S4A9 Cluster: Predicted protein; n=2; Viridiplantae|Rep: Predicted protein - Ostreococcus lucimarinus CCE9901 Length = 3608 Score = 128 bits (309), Expect = 1e-27 Identities = 293/1493 (19%), Positives = 609/1493 (40%), Gaps = 136/1493 (9%) Query: 150 TIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXX 209 ++ E+ +L +++ E LQ+ N+ ++ EA + Sbjct: 1005 SLLERSISLRAKELQNITSEPQYQRLQKSFNDLKRLSEAAERKLQEKERKIKSLKADSKE 1064 Query: 210 XXEDTK---QQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEAN-KLLEAARF 265 + K ++ ++E+ + K+E+ ++ IES + + S E A EA RF Sbjct: 1065 SAAELKALTSELASVKEDLKYIRDIAKEERDEQIQRIESLMLEVDSFENAKFDGEEAVRF 1124 Query: 266 E---ISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMT 322 L K+ E E LA+ E EE +LE+ ++T Sbjct: 1125 RNEAAKLRGMKIRLEAE-LKLSQDLAETASSELARAREEHDVVITQLSEEIAALEL-DIT 1182 Query: 323 ELTKKIELLEHLNCQIR-QTNKELENKLATMGT-----ESKAVSSPSKKGSPLISRKSGR 376 ++ IE LE I + +LE+ LA + T + K+ S + + + +++ Sbjct: 1183 VKSEAIEKLESKTNNIEVKLGSDLESALAKLNTTLEELDKKSTDFASLESASVEQKRNFE 1242 Query: 377 NTASKMKSPW--SQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTX 434 +++ S+ + L QD D I E EMV + L++ + + + SE+D Sbjct: 1243 KHVDELEKRLGASEAEVQRLIQDRDLAI---EAKDNEMVSKILSQSAIVSD-LESERDAL 1298 Query: 435 XXXXXXXXXGKDTLIAQLQ--LEHQQHMEGPSLIHVGTNTEDVNE-IAKVQEQLKQELND 491 +D+ +A ++ LE Q + V + ++ + ++ L+ EL Sbjct: 1299 RSQLADLSSARDSELASVRADLESQLREREEDIERVRSELDESKAALESERDALQSELER 1358 Query: 492 EIKDVNVKD-----LIEKLKSAEEQI-TQLNDEIDAANKNMIKVKSNHKLKLKQMQKTID 545 + V D ++ L+S + + +QL D A + + V+++ + +L++ ++ I+ Sbjct: 1359 VLSQVPEVDASQSAIVSDLESERDALRSQLADLSSARDSELASVRADLESQLREREEDIE 1418 Query: 546 NFSKVSDSNKEIVR-----LTEELHHL-----------SQKVAELEEEKGNLQLHLVDYD 589 D +K + L EL + S V++LE E+ L+ L D Sbjct: 1419 RVRSELDESKAALESERDALQSELERVLSQVPEVDASQSAAVSDLESERDALRSQLADLS 1478 Query: 590 SGRMIESDVYKKMIEMENLAETRLKAI----SLLESQKFDLVQELHILQQKYDEVEDKLA 645 S R +S++ ++E+ R + I S L+ K L E LQ + + V ++ Sbjct: 1479 SAR--DSELASVRADLESQLREREEDIERVRSELDESKAALESERDALQSELERVLSQVP 1536 Query: 646 DISQLQSDQVCSEIKSVH--LEEQI-DALSASKKELALVIENLKLDKEQLYGTIKDLEND 702 ++ QS + S+++S L Q+ D SA ELA V +L+ QL +D+E Sbjct: 1537 EVDASQS-AIVSDLESERDALRSQLADLSSARDSELASVRADLE---SQLREREEDIERV 1592 Query: 703 KEDIMNKLQNYIQENMDLTDKLEKMSA---EKISELLAKINHEEQSKIQTQFGIDAKIQE 759 + ++ E L +LE++ + E + A ++ E + + + Sbjct: 1593 RSELDESKAALESERDALQSELERVLSQVPEVDASQSAAVSDLESERDALRSQLADLSSA 1652 Query: 760 RDLYIENIESEL-SKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTI 818 RD + ++ ++L S+ + R +E + +++ + +LE + D L S L+ E Sbjct: 1653 RDSELASVRADLESQLREREEDIERVRSELDESKAALESERDALQSELERVLSQVPEVDA 1712 Query: 819 QEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNA 878 + +V+ L D + QL ++ ++ L +L+ L + ++ Sbjct: 1713 SQSAIVSDLESERD---ALRSQLADLS------SARDSELASVRADLESQLREREED--- 1760 Query: 879 LVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIES 938 +E+ R++L ES++ +++ L+S L+R+ + + + + DLE E + + S Sbjct: 1761 -IERV-RSELDESKAA-LESERDALQSELERVLSQVPEVDASQSAAVSDLESERDA-LRS 1816 Query: 939 AIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQT 998 + D + ++ LE+QL+E + +IE + ++E +K LE ++ Sbjct: 1817 QLADLSSARDSELASVR--ADLESQLREREEDIERVRSELDE-SKAALES-----ERDAL 1868 Query: 999 QSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYE--SKLAQFTTK 1056 QS E+ ++++ +++A ++ + + + Q++ +S D E S A ++ Sbjct: 1869 QSE--LERVLSQVPEVDASQSAAVSDLESERDALRS-QLADLSSARDSELASVRADLESQ 1925 Query: 1057 LENMEEEMQRVSKQLLDSKQHNE-ELQILVREQDDQIKELKETKLTFEMNIPKTEGMIIS 1115 L EE+++RV +L +SK E E L E + + ++ E + + E Sbjct: 1926 LREREEDIERVRSELDESKAALESERDALQSELERVLSQVPEVDASQSAAVSDLESE--R 1983 Query: 1116 STIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQE-RSVLQEQSAKLNTELQECYTK 1174 + D ++ +++E EE I+ RS L E A L +E + Sbjct: 1984 DALRSQLADLSSARDSELASVRADLESQLREREEDIERVRSELDESKAALESERDALQS- 2042 Query: 1175 IIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFE 1234 +LE + +++ D ++ L+S E D L S ++ELR S ++ + Sbjct: 2043 --ELERVLSQVPEVDASQSAAMSDLES-------ERDALRSQLSELRQMSSESIAGLQQQ 2093 Query: 1235 IAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQ------LLDSVQSSTQEETNKIVT 1288 + + A A +KT EL+ + E+ + L D + E +K Sbjct: 2094 LVAFSAE--ADSAASLRKTVKELKATIRQRENLLSETVFDPMLNDDLDRMNDELASKSAE 2151 Query: 1289 MEQV-TSLQ---NKLQDKEEHLRNLQEKYADVINQIEILRSEI--EDEKVAFXXXXXXXX 1342 ++ T LQ NKL+++EE + Q + VI++I R+E+ +EK+A Sbjct: 2152 LDSARTKLQSTLNKLKEREEQAESSQAVASAVIDEI---RAELLNANEKLAARESYANAV 2208 Query: 1343 XXXXXXXXDLRTENQSYKQMQEQSIL-NINEENAQLKKSSXXXXXXXXXXXXRVNDAE-A 1400 R + + +++ IL + + L + + D E + Sbjct: 2209 ELALRSELTEREKEIALLRVKVAKILDDSTNKQTSLTTALDSAQSEIERLTRELEDVEQS 2268 Query: 1401 KVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIED------LTYE 1454 K + + E +S+I + + DE + + EK + D T Sbjct: 2269 KQVAMKESFERNESQIASLNAAHRELDQRLRDELDAALKAKASLEKELSDRAESTAATET 2328 Query: 1455 KESELAILRLKMHENANHYETMQKESEIERVK----LIEELNVKITESVSLNKQVAELNK 1510 + L + + T + E E VK L+ EL+ E+ + + A+L + Sbjct: 2329 AKRNAEALSESLQSQLDALSTQRAELEQRLVKREEELVAELDAAKHEATAQAARFAQLGE 2388 Query: 1511 ALEEEV-AKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFAS 1562 A + + +++++ +E E E+ + +E+T+ + +A +++ ++ AS Sbjct: 2389 AASDHAHDEVDKLKSEVERLEFELGAVKNELTSATSTAKADIARLTDELASAS 2441 Score = 105 bits (253), Expect = 8e-21 Identities = 258/1341 (19%), Positives = 561/1341 (41%), Gaps = 123/1341 (9%) Query: 323 ELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKM 382 EL K++ + + + + LE++ T+ T+ K+++ + + + + R + Sbjct: 633 ELLAKLQTAQDQSDTDAEAIRRLEHETETLQTKLKSLTEQLSVANASVEQINSRRFDLE- 691 Query: 383 KSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXX 442 SQL ++ D N+ + + +E + + + K+L + + ++ + Sbjct: 692 ----SQLRAKATELDL-ANANRADTSLVEELRRQV-KNLSTEICWLRDQKSREGSEAEAV 745 Query: 443 XGKDTLIAQLQLEHQQH-MEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEI-KDVNVKD 500 K A+ QLE Q++ +E + + ++ I + E+L E++++ K + + Sbjct: 746 LQKQLAEARTQLEIQRNELEIEAKAEISELKRSMDVIREEMERLTSEMSEKTEKSLEYQR 805 Query: 501 LIEKLKSAEEQITQLND----EIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVS----D 552 ++++ + E +T+ + ID + KN+ + + + K K + + + +S Sbjct: 806 IVQERQKEIESLTKNKELAARAIDESKKNLAQAQEALETKQKALDDRVSQVASLSLDLAA 865 Query: 553 SNKEIVRLTEELHHLSQKVAELEEEKGNLQLH-------LVDYDSGRMIESDVYKKMI-- 603 S ++ + L EL Q+ ELEE +L+ + L D D E+D + M+ Sbjct: 866 SEEKTLTLERELSASCQRSQELEELISSLRSYSESRDALLADIDLLLGNENDEREAMLRG 925 Query: 604 -----EMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLA------DISQLQS 652 ++ + RL+ +LE +K D Q L + +E++ + A D+ Q+ S Sbjct: 926 SKNASDLVERIQKRLRREVVLE-KKLDQAQLLEQVGLTVEELKTREAASLWWKDLVQIGS 984 Query: 653 DQVCSEIKSVHLEEQIDALSAS--KKELALVIENLK-LDKEQLYGTIKDLENDKEDIMNK 709 + I+S ++ ++AS ++ ++L + L+ + E Y ++ ND + + Sbjct: 985 -KALETIQSTAVDLSKGTVTASLLERSISLRAKELQNITSEPQYQRLQKSFNDLKRLSEA 1043 Query: 710 LQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIES 769 + +QE L+ S E +EL A + K ++ D +ERD I+ IES Sbjct: 1044 AERKLQEKERKIKSLKADSKESAAELKALTSELASVKEDLKYIRDIAKEERDEQIQRIES 1103 Query: 770 ---ELSKYKS------RICRLEESIAVMEDRRYSLERK----ADQLGSYLQEKQKAYSEY 816 E+ +++ R A + + LE + D + E +A E+ Sbjct: 1104 LMLEVDSFENAKFDGEEAVRFRNEAAKLRGMKIRLEAELKLSQDLAETASSELARAREEH 1163 Query: 817 TIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHY 876 + +L +A L + D V+ + +E K K N I ++ +L+ +L+ + Sbjct: 1164 DVVITQLSEEIAAL-ELDITVKSEAIE-----KLESKTNNIEVKLGSDLESALAKLNTTL 1217 Query: 877 NALVEKANRTDLAESEST------KYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEI 930 L +K+ TD A ES ++ + +LE L E Q LI + IE + Sbjct: 1218 EELDKKS--TDFASLESASVEQKRNFEKHVDELEKRLGASEAEVQRLIQDRDLAIEAKDN 1275 Query: 931 EFNTQI--ESAI-RDKKVLNEKYEKNI-EYVTQLEAQLQEYKNNIEN-LNMNVEELNKMN 985 E ++I +SAI D + + + + + +++L + ++E+ L E++ ++ Sbjct: 1276 EMVSKILSQSAIVSDLESERDALRSQLADLSSARDSELASVRADLESQLREREEDIERVR 1335 Query: 986 LELIDKH--VQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMV 1043 EL + ++ ++ E+ ++++ +++A ++ + + +Q++ +S Sbjct: 1336 SELDESKAALESERDALQSELERVLSQVPEVDASQSAIVSDLESERDAL-RSQLADLSSA 1394 Query: 1044 SDYE--SKLAQFTTKLENMEEEMQRVSKQLLDSKQHNE-ELQILVREQDDQIKELKETKL 1100 D E S A ++L EE+++RV +L +SK E E L E + + ++ E Sbjct: 1395 RDSELASVRADLESQLREREEDIERVRSELDESKAALESERDALQSELERVLSQVPEVDA 1454 Query: 1101 TFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQE-RSVLQE 1159 + + E + D ++ +++E EE I+ RS L E Sbjct: 1455 SQSAAVSDLESE--RDALRSQLADLSSARDSELASVRADLESQLREREEDIERVRSELDE 1512 Query: 1160 QSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAE 1219 A L +E + +LE + +++ D ++ L+S E D L S +A+ Sbjct: 1513 SKAALESERDALQS---ELERVLSQVPEVDASQSAIVSDLES-------ERDALRSQLAD 1562 Query: 1220 LRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSST 1279 L SSA D + + L +RE D ++ EL +A ES+ D++QS Sbjct: 1563 L----SSARDSELASVRADLESQLREREEDIERVRSELDESKAALESE----RDALQSEL 1614 Query: 1280 QEETNKIVTMEQVTSLQ-NKLQDKEEHLRN-LQEKYADVINQIEILRSEIEDEKVAFXXX 1337 + +++ ++ S + L+ + + LR+ L + + +++ +R+++E + Sbjct: 1615 ERVLSQVPEVDASQSAAVSDLESERDALRSQLADLSSARDSELASVRADLESQLREREED 1674 Query: 1338 XXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVND 1397 L +E + + E+ + + E +A ++ Sbjct: 1675 IERVRSELDESKAALESERDALQSELERVLSQVPEVDA----------SQSAIVSDLESE 1724 Query: 1398 AEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKES 1457 +A +L +DSE+ + L +R ++ E VR +L E + +E +S Sbjct: 1725 RDALRSQLADLSSARDSELASVRADLESQLREREEDIERVRSELDESKAALESERDALQS 1784 Query: 1458 ELAILRLKMHE----NANHYETMQKESEIERVKLIEELNVKITESVS----LNKQVAELN 1509 EL + ++ E + ++ E + R +L + + + +E S L Q+ E Sbjct: 1785 ELERVLSQVPEVDASQSAAVSDLESERDALRSQLADLSSARDSELASVRADLESQLRERE 1844 Query: 1510 KALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRD 1569 + +E ++ +E + ALE++ + + + + + V AS S + D + + Sbjct: 1845 EDIERVRSELDESKAALESERDALQSELERVLSQVPEVDASQSAAVSDLESERDALRSQL 1904 Query: 1570 EQLDNTMNKELLDAVPRAELD 1590 L + + EL A RA+L+ Sbjct: 1905 ADLSSARDSEL--ASVRADLE 1923 Score = 101 bits (242), Expect = 2e-19 Identities = 284/1594 (17%), Positives = 611/1594 (38%), Gaps = 124/1594 (7%) Query: 61 LENAALVSKRIKEHRKATAELLGRPFVPGISESLANTLKQKEILMEKIKQYKELSKRSST 120 LE+A++ KR E K EL R G SE+ L Q L + K + +SK S Sbjct: 1230 LESASVEQKRNFE--KHVDELEKRL---GASEAEVQRLIQDRDLAIEAKDNEMVSKILSQ 1284 Query: 121 TIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKIN 180 + + QL D++ ++ E + + L+ +++ E I ++ +++ Sbjct: 1285 SAI---VSDLESERDALRSQLADLSSARDS--ELASVRADLESQLREREEDIERVRSELD 1339 Query: 181 EKDQIIEAKNKATTXXXXXXXXXX----XXXXXXXEDTKQQMTKMQENFIAMEAEWKDEK 236 E +E++ A D + + ++ + + E Sbjct: 1340 ESKAALESERDALQSELERVLSQVPEVDASQSAIVSDLESERDALRSQLADLSSARDSEL 1399 Query: 237 QRLLKDIESK-DVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXL 295 + D+ES+ R +E L+ ++ + E L ELE+ Sbjct: 1400 ASVRADLESQLREREEDIERVRSELDESKAALESERDALQSELERVLSQVPEVDASQSAA 1459 Query: 296 AKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIEL-LEHLNCQIRQTNKELENKLATMGT 354 ++++ + S + + + +E L I + EL+ A + + Sbjct: 1460 VSDLESERDALRSQLADLSSARDSELASVRADLESQLREREEDIERVRSELDESKAALES 1519 Query: 355 ESKAVSSPSKKGSPLISRKSGRNTA--SKMKSPWSQLSSETLNQDTDKKINKNEIAKLEM 412 E A+ S ++ + +A S ++S L S+ + + + +E+A + Sbjct: 1520 ERDALQSELERVLSQVPEVDASQSAIVSDLESERDALRSQLADLSSARD---SELASVRA 1576 Query: 413 VIQS-LNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQ--LEHQQHMEGPSLIHVG 469 ++S L + D E V SE D +D L ++L+ L ++ V Sbjct: 1577 DLESQLREREEDIERVRSELDESKAALESE---RDALQSELERVLSQVPEVDASQSAAVS 1633 Query: 470 TNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKV 529 + + + L + E+ V DL +L+ EE I ++ E+D ++ + Sbjct: 1634 DLESERDALRSQLADLSSARDSELASVRA-DLESQLREREEDIERVRSELD---ESKAAL 1689 Query: 530 KSNHKLKLKQMQKTIDNFSKVSDSNKEIVR-LTEELHHLSQKVAELEEEKGNLQLHLVDY 588 +S ++++ + +V S IV L E L ++A+L + + +L V Sbjct: 1690 ESERDALQSELERVLSQVPEVDASQSAIVSDLESERDALRSQLADLSSARDS-ELASVRA 1748 Query: 589 DSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVE-DKLADI 647 D +ES + ++ ++E + ++ + LES++ L EL + + EV+ + A + Sbjct: 1749 D----LESQLREREEDIERVRSELDESKAALESERDALQSELERVLSQVPEVDASQSAAV 1804 Query: 648 SQLQSDQVCSEIKSVHLEEQIDA-LSASKKELALVIENLKLDKEQLYGTIKDLENDKEDI 706 S L+S++ + L D+ L++ + +L + + D E++ + + + E Sbjct: 1805 SDLESERDALRSQLADLSSARDSELASVRADLESQLREREEDIERVRSELDESKAALESE 1864 Query: 707 MNKLQNYIQENMDLTDKLEKMSAEKISEL----------LAKINHEEQSKIQT-QFGIDA 755 + LQ+ ++ + +++ + +S+L LA ++ S++ + + +++ Sbjct: 1865 RDALQSELERVLSQVPEVDASQSAAVSDLESERDALRSQLADLSSARDSELASVRADLES 1924 Query: 756 KIQERDLYIENIESELSKYKSRI--------CRLEESIAVMEDRRYS-------LERKAD 800 +++ER+ IE + SEL + K+ + LE ++ + + S LE + D Sbjct: 1925 QLREREEDIERVRSELDESKAALESERDALQSELERVLSQVPEVDASQSAAVSDLESERD 1984 Query: 801 QLGSYLQEKQKAY-SEYTIQEDELVNRLAVLMDHDRVVEKQLLE----IEHENKELQKKN 855 L S L + A SE +L ++L + V +L E +E E LQ + Sbjct: 1985 ALRSQLADLSSARDSELASVRADLESQLREREEDIERVRSELDESKAALESERDALQSEL 2044 Query: 856 QILL----EENQNLQISLSDMQQHYNALVEKANRTDLAESES-TKYQTQL------RDLE 904 + +L E + + ++SD++ +AL + + SES Q QL D Sbjct: 2045 ERVLSQVPEVDASQSAAMSDLESERDALRSQLSELRQMSSESIAGLQQQLVAFSAEADSA 2104 Query: 905 SNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQL 964 ++L++ E + I Q++ + E F+ + D +N++ + +L Sbjct: 2105 ASLRKTVKELKATIRQRENLLS--ETVFDPMLND---DLDRMNDELASKSAELDSARTKL 2159 Query: 965 QEYKNNIENLNMNVEELNKMNLELIDKHVQK--QQTQSPDYTEQYINEIN-KLNALLKQK 1021 Q N ++ E + +ID+ + + E Y N + L + L ++ Sbjct: 2160 QSTLNKLKEREEQAESSQAVASAVIDEIRAELLNANEKLAARESYANAVELALRSELTER 2219 Query: 1022 DEEIIALNQKI-------NNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDS 1074 ++EI L K+ N Q S + + +S++ + T +LE++E+ Q K+ + Sbjct: 2220 EKEIALLRVKVAKILDDSTNKQTSLTTALDSAQSEIERLTRELEDVEQSKQVAMKESFER 2279 Query: 1075 KQHN-EELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXX 1133 + L RE D ++++ + L + ++ K ST N + Sbjct: 2280 NESQIASLNAAHRELDQRLRDELDAALKAKASLEKELSDRAEST-AATETAKRNAEALSE 2338 Query: 1134 XXXXXXXXLKVQEEEEFIQERSVLQEQS--AKLNTELQECYTKIIQLETLNTELTGHDVV 1191 L Q E +++R V +E+ A+L+ E + + L + H Sbjct: 2339 SLQSQLDALSTQRAE--LEQRLVKREEELVAELDAAKHEATAQAARFAQLGEAASDH--- 2393 Query: 1192 NQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQ 1251 +++++LKS++E+L E + + + S+ + + + E+A A R+A Sbjct: 2394 AHDEVDKLKSEVERLEFELGAVKNELTSATSTAKADIARLTDELASA----SAARDA-VA 2448 Query: 1252 KTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQE 1311 +T H S S +E + + E + + ++ S + E +R Sbjct: 2449 ETAHPEEDGSSESASAFEAMRRDMTRLESELAAALAELAELESPRESESSDTEAIREFTT 2508 Query: 1312 KYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNIN 1371 ++IE L E+ED + + L ++ Q + Sbjct: 2509 ALDSAQSEIERLTRELEDVEQSKQVAMKESFERNESQIASLNAAHRELDQRLRDELDAAL 2568 Query: 1372 EENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSE-------IYQKTHEYT 1424 + A L++ S + N AEA L QL+ ++ + ++ E Sbjct: 2569 KAKASLEERSDRAESTAATETAKRN-AEALSESLQSQLDALSTQRAELEQRLVKREEELV 2627 Query: 1425 ITLTQRNDEFENVRQQLVEYEKRIEDLTYEK----ESELAILRLKMHENANHYETMQKES 1480 L E + + + D +++ +SE+ L ++ N + + Sbjct: 2628 AELDAAKHEATAQAARFAQLGEAASDHAHDEVDKLKSEVERLEFELGAVKNELTSATSTA 2687 Query: 1481 EIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEI 1540 + + +L +EL ++ + E + M+ + E E+ E+ Sbjct: 2688 KADIARLTDELASASAARDAVAETAHPEEDGSSESASAFEAMRRDMTRLESELAAALAEL 2747 Query: 1541 TNLQNMVRASSSKIQ--KHVSFASDTKQGRDEQL 1572 L++ + SS + + + A D+ Q E+L Sbjct: 2748 AELESPRESESSDTEAIREFTTALDSAQSEIERL 2781 Score = 97.5 bits (232), Expect = 3e-18 Identities = 308/1658 (18%), Positives = 648/1658 (39%), Gaps = 139/1658 (8%) Query: 11 SEMELSEETTARLPSSEVSSVAGXXXXXXXXXXXXXXXERQIKFERAQKCLEN--AALVS 68 S++E SE R +++SS ER+ ER + L+ AAL S Sbjct: 1977 SDLE-SERDALRSQLADLSSARDSELASVRADLESQLREREEDIERVRSELDESKAALES 2035 Query: 69 KRIKEHRKATAELLGRPFVPGISESLANTLK-QKEILMEKIKQYKELSKRSSTTIVRXXX 127 +R + L P V + + L+ +++ L ++ + +++S S + + Sbjct: 2036 ERDALQSELERVLSQVPEVDASQSAAMSDLESERDALRSQLSELRQMSSESIAGLQQQLV 2095 Query: 128 XXXXXXXXXXXXQLGDVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIE 187 + V L TI++++N LS + + + D +++N+ E Sbjct: 2096 AFSAEADSAASLRK-TVKELKATIRQRENLLSET-----VFDPMLNDDLDRMND-----E 2144 Query: 188 AKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKD 247 +K+ ++ ++Q Q A+ E + E + + +++ Sbjct: 2145 LASKSAELDSARTKLQSTLNKL--KEREEQAESSQAVASAVIDEIRAELLNANEKLAARE 2202 Query: 248 VRISSLEEA--NKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCE 305 +++E A ++L E + EI+L K+A+ L+ A+ IE Sbjct: 2203 SYANAVELALRSELTEREK-EIALLRVKVAKILDDSTNKQTSLTTALDS-AQSEIERLTR 2260 Query: 306 EKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKL-ATMGTESKAVSSPSK 364 E ++E+ S ++A + + LN R+ ++ L ++L A + ++ S Sbjct: 2261 ELEDVEQ--SKQVAMKESFERNESQIASLNAAHRELDQRLRDELDAALKAKASLEKELSD 2318 Query: 365 KG-SPLISRKSGRNTASKMKSPWSQLSS-ETLNQDTDKKINKNE---IAKLEMVIQSLNK 419 + S + + RN + +S SQL + T + ++++ K E +A+L+ Sbjct: 2319 RAESTAATETAKRNAEALSESLQSQLDALSTQRAELEQRLVKREEELVAELDAAKHEATA 2378 Query: 420 DLVD-KEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIH--VGTNTEDVN 476 + + D + L +L + S + T+++ Sbjct: 2379 QAARFAQLGEAASDHAHDEVDKLKSEVERLEFELGAVKNELTSATSTAKADIARLTDELA 2438 Query: 477 EIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLK 536 + ++ + + + E + + ++ +T+L E+ AA + +++S + + Sbjct: 2439 SASAARDAVAETAHPE--EDGSSESASAFEAMRRDMTRLESELAAALAELAELESPRESE 2496 Query: 537 LKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQ--KVAELEEEKGN----LQLHLVDYDS 590 + + + + + EI RLT EL + Q +VA E + N L+ + Sbjct: 2497 SSDTEAIREFTTALDSAQSEIERLTRELEDVEQSKQVAMKESFERNESQIASLNAAHREL 2556 Query: 591 GRMIESDVYKKMIEMENLAET--RLKAISLLESQKFDLVQELHILQQKYDEVEDKLADIS 648 + + ++ + +L E R ++ + E+ K + LQ + D + + A++ Sbjct: 2557 DQRLRDELDAALKAKASLEERSDRAESTAATETAKRNAEALSESLQSQLDALSTQRAELE 2616 Query: 649 QL---QSDQVCSEIKSVHLEEQIDALS-ASKKELALVIENLKLDKEQLYGTIKDLENDKE 704 Q + +++ +E+ + E A A E A + ++DK L ++ LE + Sbjct: 2617 QRLVKREEELVAELDAAKHEATAQAARFAQLGEAASDHAHDEVDK--LKSEVERLEFELG 2674 Query: 705 DIMNKLQNYIQ----ENMDLTDKLEKMSAEKISELLAKINH-EEQSKIQTQFGIDAKIQE 759 + N+L + + LTD+L SA + + +A+ H EE ++ +A Sbjct: 2675 AVKNELTSATSTAKADIARLTDELASASAAR--DAVAETAHPEEDGSSESASAFEA--MR 2730 Query: 760 RDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQ 819 RD+ +ESEL+ + + LE ++ L S E ++ E ++ Sbjct: 2731 RDM--TRLESELAAALAELAELESPRESESSDTEAIREFTTALDSAQSEIERLTRE--LE 2786 Query: 820 EDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQ----ILLEENQNLQISLSDMQQH 875 + E ++A+ +R E Q+ + ++EL ++ + L+ +L+ SD + Sbjct: 2787 DVEQSKQVAMKESFERN-ESQIASLNAAHRELDQRLRDELDAALKAKASLEKERSDRAES 2845 Query: 876 YNALVEKANRTDLAESESTKYQ-----TQLRDLESNLKRITHEHQTLIVQKKKEIEDLEI 930 A E A R A SES + Q TQ +LE L + E + K E Sbjct: 2846 -TAATETAKRNAEALSESLQSQLDALSTQRAELEQRLVKREEELVAELDAAKHEATAQAA 2904 Query: 931 EFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVE-ELNKMNLELI 989 F Q+ A D +++ +K V +LE +L KN + + + ++ ++ EL Sbjct: 2905 RF-AQLGEAASDHA--HDEVDKLKSEVERLEFELGAVKNELTSATSTAKADIARLTDELA 2961 Query: 990 DKHVQKQ---QTQSP--DYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVS 1044 + +T P D + + + + + + + E+ A ++ + S S Sbjct: 2962 SASAARDAVAETAHPEEDGSSESASAFEAMRRDMTRLESELAAALAELAELESPRESESS 3021 Query: 1045 DYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNE-ELQILVREQDDQIKELKETKLTFE 1103 D E+ + +FTT L++ + E++R++++L D +Q + ++ + QI L + Sbjct: 3022 DTEA-IREFTTALDSAQSEIERLTRELEDVEQSKQVAMKESFERNESQIASLNAAHRELD 3080 Query: 1104 MNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAK 1163 + + + + ++ + + E + + S +E AK Sbjct: 3081 QRLRDELDAALKAKASLEKELSDRAESTAATEIAKRNAEALSESLQSQLDASRAEE--AK 3138 Query: 1164 LNTELQECYTKII--QLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELR 1221 L EL + ++ ++ L+ E+T +QE L T +ST+A L Sbjct: 3139 LRDELNH-FQELAREEISALHNEITEIKFTSQESQASLGESPWPSIT-----ISTLAGLN 3192 Query: 1222 SSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQE 1281 +S + G E + W +H A +K+ + +L E++YEQ + +Q S ++ Sbjct: 3193 EMMSRG-SEFGSEGLD-WLEHAAHEVQALEKSVLDATAELELRENEYEQTIAQLQDSVRD 3250 Query: 1282 -ETN-------KIVTMEQVTSLQNKLQDKEEHLRNLQEKYA-----DVINQIEILRSEIE 1328 ET+ + V L +KL +++E L +L+ + A DV ++E+ S + Sbjct: 3251 AETDLNSQKSLASAALSDVEHLNDKLAERDEELASLRLELANLVSDDVTRELELTISNLR 3310 Query: 1329 DEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQ----------EQSILNINEENAQLK 1378 + A D R ++ ++Q + SI I+ N +L Sbjct: 3311 IQLTAKDNELNGAVASLNDLENDKRAIEEAMSELQAAADMQAARVQTSIEQISSLNVELA 3370 Query: 1379 KSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVR 1438 K S + A E L + + K L + + E++R Sbjct: 3371 KRSAALDASWDNLSHAESRARFAEQERDDVRRLFEERLAVKER----ALRETQGDVEHLR 3426 Query: 1439 QQLVEYEKRIEDLTYEK-ESELAILRLK-MHENANHYETMQKESEIERVKLIEELNVKIT 1496 Q + + +++ Y + E+E E+A+ +E M++ + +L EL + Sbjct: 3427 QTVRNLQDKLKAHRYARSETEAGHPEEDGSSESASAFEAMRR----DMTRLESELAAALA 3482 Query: 1497 ESVSLNKQVAELNKALEEEVAKT---NEMQTALENQEIEIVTLNDEITNLQNMVRASSSK 1553 E +AEL E E + T E TAL++ + EI L E+ +++ + + + Sbjct: 3483 E-------LAELESPRESESSDTEAIREFTTALDSAQSEIERLTRELEDVEQSKQVAMKE 3535 Query: 1554 IQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDL 1591 + + +LD + E LDA +A+ L Sbjct: 3536 SFERNESQIASLNAAHRELDQRLRDE-LDAALKAKASL 3572 Score = 66.1 bits (154), Expect = 8e-09 Identities = 185/950 (19%), Positives = 375/950 (39%), Gaps = 96/950 (10%) Query: 714 IQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSK 773 I E D D E S+ +I+EL I E + Q + K Q D I +E L K Sbjct: 525 IVELQDSLDSGEARSSARIAELRGAIESLELKLTRLQ---EEKTQSVDNRIL-LEDRLQK 580 Query: 774 YKSRICRLEESIAVMED----RRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAV 829 I + E V ++ R LE + + LQ + + + EL+ +L Sbjct: 581 LNLEIDSVRERERVAQEDWQRERLRLEVELEASVKELQTATRTVDDALKAKLELLAKLQT 640 Query: 830 LMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLS-------DMQQHYNALVEK 882 D + + +EHE + LQ K + L E+ S+ D++ A + Sbjct: 641 AQDQSDTDAEAIRRLEHETETLQTKLKSLTEQLSVANASVEQINSRRFDLESQLRAKATE 700 Query: 883 -----ANRTDLAESESTKYQTQ--------LRDLES---NLKRITHEHQTLIVQKKKEIE 926 ANR D + E + Q + LRD +S + + Q + + EI+ Sbjct: 701 LDLANANRADTSLVEELRRQVKNLSTEICWLRDQKSREGSEAEAVLQKQLAEARTQLEIQ 760 Query: 927 --DLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKM 984 +LEIE +I R V+ E+ E+ +++ + EY+ ++ +E L K Sbjct: 761 RNELEIEAKAEISELKRSMDVIREEMERLTSEMSEKTEKSLEYQRIVQERQKEIESLTK- 819 Query: 985 NLELIDKHVQKQ-----QTQSPDYTEQ-----YINEINKLNALLKQKDEEIIALNQKIN- 1033 N EL + + + Q Q T+Q ++++ L+ L +E+ + L ++++ Sbjct: 820 NKELAARAIDESKKNLAQAQEALETKQKALDDRVSQVASLSLDLAASEEKTLTLERELSA 879 Query: 1034 NAQVS-----YMSMVSDY-ESK---LAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQIL 1084 + Q S +S + Y ES+ LA L N +E + + + ++ E +Q Sbjct: 880 SCQRSQELEELISSLRSYSESRDALLADIDLLLGNENDEREAMLRGSKNASDLVERIQKR 939 Query: 1085 VREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKV 1144 +R + K+L + +L ++ + E + D L Sbjct: 940 LRREVVLEKKLDQAQLLEQVGLTVEELKTREAASLWWKDLVQIGSKALETIQSTAVDLSK 999 Query: 1145 QEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLE 1204 + ERS+ N + Y + L+ +L + ++ + + K++ Sbjct: 1000 GTVTASLLERSISLRAKELQNITSEPQYQR---LQKSFNDLKRLSEAAERKLQEKERKIK 1056 Query: 1205 QLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAF 1264 L ++ + + L S ++S + + I ++ K+ +R+ Q+ E L +++ +F Sbjct: 1057 SLKADSKESAAELKALTSELASVKEDLKY-IRDIAKE---ERDEQIQRIE-SLMLEVDSF 1111 Query: 1265 E-SKY--EQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQ-- 1319 E +K+ E+ + + + KI ++ Q+ + L +E++ VI Q Sbjct: 1112 ENAKFDGEEAVRFRNEAAKLRGMKIRLEAELKLSQDLAETASSELARAREEHDVVITQLS 1171 Query: 1320 --IEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTE----NQSYKQMQEQSILNINEE 1373 I L +I + A DL + N + +++ ++S + E Sbjct: 1172 EEIAALELDITVKSEAIEKLESKTNNIEVKLGSDLESALAKLNTTLEELDKKSTDFASLE 1231 Query: 1374 NAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQ----LELKDSEIYQKTHEYTITLTQ 1429 +A +++ R+ +EA+V L +E KD+E+ K + ++ Sbjct: 1232 SASVEQ-KRNFEKHVDELEKRLGASEAEVQRLIQDRDLAIEAKDNEMVSKILSQSAIVSD 1290 Query: 1430 RNDEFENVRQQLVEYEKRIEDLTYEKESELAILRL----KMHENANHYETMQKESEIERV 1485 E + +R QL DL+ ++SELA +R ++ E E ++ E + + Sbjct: 1291 LESERDALRSQLA-------DLSSARDSELASVRADLESQLREREEDIERVRSELDESKA 1343 Query: 1486 KLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLND-EI---- 1540 L E + +E + QV E++ + V+ + AL +Q ++ + D E+ Sbjct: 1344 ALESERDALQSELERVLSQVPEVDASQSAIVSDLESERDALRSQLADLSSARDSELASVR 1403 Query: 1541 TNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMN--KELLDAVPRAE 1588 +L++ +R I++ S ++K + + D + + +L VP + Sbjct: 1404 ADLESQLREREEDIERVRSELDESKAALESERDALQSELERVLSQVPEVD 1453 Score = 63.7 bits (148), Expect = 4e-08 Identities = 226/1146 (19%), Positives = 447/1146 (39%), Gaps = 110/1146 (9%) Query: 449 IAQL-QLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELND--EIKDVNVKDLIEK- 504 +A+L +LE + E + T ++ E+L +EL D + K V +K+ E+ Sbjct: 2483 LAELAELESPRESESSDTEAIREFTTALDSAQSEIERLTRELEDVEQSKQVAMKESFERN 2542 Query: 505 ------LKSAEEQITQ-LNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEI 557 L +A ++ Q L DE+DAA +K K++ + + + + T + ++ Sbjct: 2543 ESQIASLNAAHRELDQRLRDELDAA----LKAKASLEERSDRAESTAATETAKRNAEALS 2598 Query: 558 VRLTEELHHLSQKVAELEEEKGNLQLHLV-DYDSGRMIESDVYKKMIEM-ENLAETRLKA 615 L +L LS + AELE+ + LV + D+ + + + ++ E ++ Sbjct: 2599 ESLQSQLDALSTQRAELEQRLVKREEELVAELDAAKHEATAQAARFAQLGEAASDHAHDE 2658 Query: 616 ISLLESQKFDLVQELHILQQKYDEVEDKL-ADISQLQSDQVCSE-------IKSVHLEEQ 667 + L+S+ L EL ++ + ADI++L +D++ S ++ H EE Sbjct: 2659 VDKLKSEVERLEFELGAVKNELTSATSTAKADIARL-TDELASASAARDAVAETAHPEED 2717 Query: 668 IDALSASKKELALVIENLKLDKE--QLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLE 725 + SAS E A+ + +L+ E + +LE+ +E + + I+E T L+ Sbjct: 2718 GSSESASAFE-AMRRDMTRLESELAAALAELAELESPRESESSDTE-AIRE---FTTALD 2772 Query: 726 KMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESI 785 +E I L ++ EQSK Q + + + I ++ + ++ RL + + Sbjct: 2773 SAQSE-IERLTRELEDVEQSK---QVAMKESFERNESQIASLN---AAHRELDQRLRDEL 2825 Query: 786 AVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIE 845 + SLE++ + A + L ++L L +E++L++ E Sbjct: 2826 DAALKAKASLEKERSDRAESTAATETAKRNAEALSESLQSQLDALSTQRAELEQRLVKRE 2885 Query: 846 HE-NKELQ-KKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDL 903 E EL K++ + + Q+ + ++ + + + + E E + +L Sbjct: 2886 EELVAELDAAKHEATAQAARFAQLGEAASDHAHDEVDKLKSEVERLEFELGAVKNELTSA 2945 Query: 904 ESNLK----RITHE------HQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKN 953 S K R+T E + + + ED E + E+ RD L + Sbjct: 2946 TSTAKADIARLTDELASASAARDAVAETAHPEEDGSSESASAFEAMRRDMTRLESELAAA 3005 Query: 954 IEYVTQLEAQLQEYKNNIE-------NLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQ 1006 + + +LE+ + ++ E L+ E+ ++ EL D KQ + E+ Sbjct: 3006 LAELAELESPRESESSDTEAIREFTTALDSAQSEIERLTRELEDVEQSKQVAMKESF-ER 3064 Query: 1007 YINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQR 1066 ++I LNA ++ D+ + A+ S +SD A N E + Sbjct: 3065 NESQIASLNAAHRELDQRLRDELDAALKAKASLEKELSDRAESTAATEIAKRNAEALSES 3124 Query: 1067 VSKQLLDSKQHNEEL-------QILVREQDDQI-KELKETKLTF-EMNIPKTEGMIISST 1117 + QL S+ +L Q L RE+ + E+ E K T E E S T Sbjct: 3125 LQSQLDASRAEEAKLRDELNHFQELAREEISALHNEITEIKFTSQESQASLGESPWPSIT 3184 Query: 1118 IEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQ 1177 I ++ + L+ E E+SVL + +A+L E I Q Sbjct: 3185 ISTLAGLNEMMSRGSEFGSEGLDWLEHAAHEVQALEKSVL-DATAELELRENEYEQTIAQ 3243 Query: 1178 LE----TLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQR-G 1232 L+ T+L + ++ ++ ++L ++ L S EL + +S V + Sbjct: 3244 LQDSVRDAETDLNSQKSLASAALSDVEHLNDKLAERDEELASLRLELANLVSDDVTRELE 3303 Query: 1233 FEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVT-MEQ 1291 I+ L + L ++ + L L + E+ + +Q++ + ++ T +EQ Sbjct: 3304 LTISNL-RIQLTAKDNELNGAVASLN-DLENDKRAIEEAMSELQAAADMQAARVQTSIEQ 3361 Query: 1292 VTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXD 1351 ++SL +L + L + + ++ E +D + F D Sbjct: 3362 ISSLNVELAKRSAALDASWDNLSHAESRARFAEQERDDVRRLFEERLAVKERALRETQGD 3421 Query: 1352 LRTENQSYKQMQE----------QSILNINEENAQLKKSSX--XXXXXXXXXXXRVNDAE 1399 + Q+ + +Q+ ++ EE+ + +S + A Sbjct: 3422 VEHLRQTVRNLQDKLKAHRYARSETEAGHPEEDGSSESASAFEAMRRDMTRLESELAAAL 3481 Query: 1400 AKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQL--VEYEKRI--EDLTYEK 1455 A++ EL E + S+ + E+T L E E + ++L VE K++ ++ Sbjct: 3482 AELAELESPRESESSDT-EAIREFTTALDSAQSEIERLTRELEDVEQSKQVAMKESFERN 3540 Query: 1456 ESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAE-LNKALEE 1514 ES++A L NA H E Q +L +EL+ + SL K++++ Sbjct: 3541 ESQIASL------NAAHRELDQ--------RLRDELDAALKAKASLEKELSDRAESTAAT 3586 Query: 1515 EVAKTN 1520 E AK N Sbjct: 3587 ETAKRN 3592 >UniRef50_UPI0000D57874 Cluster: PREDICTED: similar to GRIP and coiled-coil domain-containing 2; n=1; Tribolium castaneum|Rep: PREDICTED: similar to GRIP and coiled-coil domain-containing 2 - Tribolium castaneum Length = 1323 Score = 128 bits (308), Expect = 2e-27 Identities = 197/1028 (19%), Positives = 442/1028 (42%), Gaps = 86/1028 (8%) Query: 614 KAISLLESQKFDLV---QELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDA 670 K I L K +LV + L IL QK + +D L Q +++++ + +KS E DA Sbjct: 11 KKIVLENLSKEELVKRCERLLILAQKAKQAKDAL----QEENNELKNRLKS----ESGDA 62 Query: 671 LSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAE 730 +A +IENL K Q TI+DL++ ++NK+QN Q+ L ++ +++ +E Sbjct: 63 TTA-------IIENLTQQKLQFVTTIEDLKSQNAALVNKVQNCTQD-ARLCEEKDRLESE 114 Query: 731 KIS--ELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVM 788 IS + ++ E + I ++ +++E +N+ E ++++ LEE+ + Sbjct: 115 NISYKRQIKRLTDENEQLITHLESLEKQLEE----CKNLGLE---QQNQLLMLEEANQKL 167 Query: 789 --EDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEH 846 +D L L+E +K +E +++ L + D+ + E++ Sbjct: 168 RSDDTSDKSAELQTMLSISLEEVKKLQAENNTMREKIDVLKTNLGEKDKNILTIGQELQE 227 Query: 847 ENKELQKKNQILLEENQNLQI--SLSDMQQHYNALVEK-ANRTDLAESESTKYQTQLRDL 903 + K ++ +I E +N+++ L + Y++ V K A + + + LR L Sbjct: 228 KLKLVEDLEKIKNESRENVELVEKLKGRLKFYHSKVVKLAGNVKVLKENKNEV---LRLL 284 Query: 904 ESNLKRITHEHQTLIVQKKK---EIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQL 960 ++ ++ + L V KK EI D++++ N++ I K N KY K +E + Sbjct: 285 KTYSHQVEEWKEQLGVASKKLCQEISDIKVQ-NSEYHKEIEGLKESNAKYLKQLE-AHKT 342 Query: 961 EAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQ 1020 + + + E ++ ++L + N L+ + QQT T + + + L+ L ++ Sbjct: 343 DDEKSKELGEFERISKEHKKLIEENQRLLQLQLDYQQTVE-TLTVEKESLLENLSQLEER 401 Query: 1021 KDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHN-- 1078 EEI + + + + + + E ++ + +EE++ ++L D+KQ N Sbjct: 402 HQEEIKVFDDQSKKDTIEIKNRIEENEKICIEYRKVISKLEEDLDLNLRELNDAKQKNYS 461 Query: 1079 ----------EELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNV 1128 E QI + ++ +K ++E EMN +E ++D+ N Sbjct: 462 LQEALEHSKETERQIADKTSEEILKLVQENAQLVEMNRKLQTTRDNCKQVECQTEDSTNS 521 Query: 1129 DXXXXXXXXXXXXLK-VQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTG 1187 + + + E E Q E +KL + +E K+ ET + Sbjct: 522 ELEEVVSGLKRENSELLAEMNEMNQALKERGETISKLQSHCEEVMKKLQLYETQANKNVD 581 Query: 1188 HDVVNQEQINQLKSKLEQLNTEND--NLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQ 1245 + +E I +L+ ++E+L +D + S +++L++ I + ++ + + Sbjct: 582 NISQKEEIIKKLEDEIERLKATSDLNSNTSEISDLKNEIENLKERLNSNLDSSYADSECM 641 Query: 1246 READFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTM-EQVTSLQNKLQDKEE 1304 + +TE R + E +E+ +++ + K+ + ++ QN+ D ++ Sbjct: 642 STSTISRTEESNR--MKDLEGSWEERYGKLRNLAVKLKGKVRDLSNELVKEQNEKNDIQQ 699 Query: 1305 HLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLR--TENQSYKQM 1362 + + A + Q + L+ E+++ K D + +EN+ + Sbjct: 700 KCASNVKTIATLQAQCDKLQDELDENKKQIKEYSARLDSTLAEVSKDKQKLSENEEIITI 759 Query: 1363 QEQSILNINEENAQLK--KSSXXXXXXXXXXXXRVN-----DAEAKVLELTHQLELKDSE 1415 ++ + +N+E + K N + EAK+ +LT LE K+ Sbjct: 760 LKKELEELNQEKVTTEAWKKQISGKVSTFRKELEANKVLKKEYEAKIAKLTSDLEAKEQA 819 Query: 1416 IYQKT--HEYT-ITLTQRNDEFEN---VRQQLVEYEKRIEDLTY---EKESELAILRLKM 1466 + ++ H+ T +L N E + + ++ +YE+ +++L+ +K+ E+ L+ ++ Sbjct: 820 LKAESEYHQQTKNSLEHSNIERKKNSVLNLEMQDYERSVKELSQKLEKKQEEINKLKSQL 879 Query: 1467 HENANHYETMQKESEI--ERV-KLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQ 1523 + +++++++ ER ++ E+ E ++ KQ+++L + + K +++ Sbjct: 880 ESQKSTTNAVREQNKLLEERAEEMKSEVGATQAEIIACKKQISDLESVMSSKENKIHDLT 939 Query: 1524 TALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDA 1583 LE E N+E++ + V A K+ + + +G+ L T+ +++ DA Sbjct: 940 QILETVRSE----NEELSTELSKVIAEHQKVNTSLKSEKENLKGQILGLQQTL-RDVQDA 994 Query: 1584 VPRAELDL 1591 + E +L Sbjct: 995 LKLKEDEL 1002 Score = 100 bits (240), Expect = 3e-19 Identities = 235/1148 (20%), Positives = 483/1148 (42%), Gaps = 84/1148 (7%) Query: 175 LQEKINE-KDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENF--IAMEAE 231 LQE+ NE K+++ ATT ED K Q + +A Sbjct: 44 LQEENNELKNRLKSESGDATTAIIENLTQQKLQFVTTIEDLKSQNAALVNKVQNCTQDAR 103 Query: 232 WKDEKQRLLKDIESKDVRISSLEEANKLL--EAARFEISLEHSK---LAQELEQXXXXXX 286 +EK RL + S +I L + N+ L E LE K L Q+ + Sbjct: 104 LCEEKDRLESENISYKRQIKRLTDENEQLITHLESLEKQLEECKNLGLEQQNQLLMLEEA 163 Query: 287 XXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLE----HLNCQIRQTN 342 + +S E +EE L+ N T + +KI++L+ + I Sbjct: 164 NQKLRSDDTSDKSAELQTMLSISLEEVKKLQAENNT-MREKIDVLKTNLGEKDKNILTIG 222 Query: 343 KELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKI 402 +EL+ KL + K + + S++ L+ + GR +K S++ N K+ Sbjct: 223 QELQEKLKLVEDLEK-IKNESRENVELVEKLKGR-----LKFYHSKVVKLAGNVKVLKE- 275 Query: 403 NKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGK-DTLIAQLQLEHQQHME 461 NKNE+ +L ++ ++ V S+K + I L+ + ++++ Sbjct: 276 NKNEVLRLLKTYSHQVEEWKEQLGVASKKLCQEISDIKVQNSEYHKEIEGLKESNAKYLK 335 Query: 462 GPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDA 521 L T+ E E+ + E++ +E I++ N + L++ ++ + L E ++ Sbjct: 336 --QLEAHKTDDEKSKELGEF-ERISKEHKKLIEE-NQR-LLQLQLDYQQTVETLTVEKES 390 Query: 522 ANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKV-AELEEEKG- 579 +N+ +++ H+ ++K D K + K + E++ +KV ++LEE+ Sbjct: 391 LLENLSQLEERHQEEIKVFD---DQSKKDTIEIKNRIEENEKICIEYRKVISKLEEDLDL 447 Query: 580 NL-QLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLE--SQKFDLVQELHILQQK 636 NL +L+ + + E+ + K E + +T + + L++ +Q ++ ++L + Sbjct: 448 NLRELNDAKQKNYSLQEALEHSKETERQIADKTSEEILKLVQENAQLVEMNRKLQTTRDN 507 Query: 637 YDEVEDKLADISQLQSDQVCSEIKSVHLE--EQIDALSASKKELALVIENLK------LD 688 +VE + D + + ++V S +K + E +++ ++ + KE I L+ + Sbjct: 508 CKQVECQTEDSTNSELEEVVSGLKRENSELLAEMNEMNQALKERGETISKLQSHCEEVMK 567 Query: 689 KEQLYGTI--KDLEN--DKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQ 744 K QLY T K+++N KE+I+ KL++ I E + T L ++E IS+L +I E Sbjct: 568 KLQLYETQANKNVDNISQKEEIIKKLEDEI-ERLKATSDLNSNTSE-ISDLKNEI---EN 622 Query: 745 SKIQTQFGIDAKIQERDLYIENIES---ELSKYKSRICRLEESIAVMEDRRYSLERKADQ 801 K + +D+ + + + S E ++ K EE + + L+ K Sbjct: 623 LKERLNSNLDSSYADSECMSTSTISRTEESNRMKDLEGSWEERYGKLRNLAVKLKGKVRD 682 Query: 802 LGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEE 861 L + L ++Q ++ + V +A L ++ +L E + + KE + L E Sbjct: 683 LSNELVKEQNEKNDIQQKCASNVKTIATLQAQCDKLQDELDENKKQIKEYSARLDSTLAE 742 Query: 862 NQNLQISLSDMQQHYNAL---VEKANRTDLAESE-----STKYQTQLRDLESNLKRITHE 913 + LS+ ++ L +E+ N+ + S K T ++LE+N K + E Sbjct: 743 VSKDKQKLSENEEIITILKKELEELNQEKVTTEAWKKQISGKVSTFRKELEAN-KVLKKE 801 Query: 914 HQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVL-NEKYEKNIEYVTQLEAQLQEYKNNIE 972 ++ I + ++E E + E + K L + E+ V LE +Q+Y+ +++ Sbjct: 802 YEAKIAKLTSDLEAKEQALKAESEYHQQTKNSLEHSNIERKKNSVLNLE--MQDYERSVK 859 Query: 973 NLNMNVE----ELNKMNLELIDKHVQKQQTQSPDYTEQYINE-INKLNALLKQKDEEIIA 1027 L+ +E E+NK+ +L QK T + + + E ++ + + EIIA Sbjct: 860 ELSQKLEKKQEEINKLKSQL---ESQKSTTNAVREQNKLLEERAEEMKSEVGATQAEIIA 916 Query: 1028 LNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVRE 1087 ++I++ + S++S E+K+ T LE + E + +S +L ++++ ++ Sbjct: 917 CKKQISDLE----SVMSSKENKIHDLTQILETVRSENEELSTELSKVIAEHQKVNTSLKS 972 Query: 1088 QDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEE 1147 + + +K + L + + + ++ + +D N V E Sbjct: 973 EKENLKG-QILGLQQTLRDVQDALKLKEDELKIVQNDYENYKVRAQSVLRQNQSRDVGLE 1031 Query: 1148 EEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLN 1207 E+ +E S L + L EL +C T + L+ N L + + S++E L Sbjct: 1032 EKLSEEVSALGVKCEALTAELNKCKTVVDDLKKENEALVHEKSEVLTKYEDVLSEVEDLK 1091 Query: 1208 TENDNLLS----TVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSA 1263 + D L + T+ E ++ S + +A+ ++Q L+++E + EL+ ++ Sbjct: 1092 SLYDQLTNKHQQTMIEHSETVRS-LKVHAETLAQCYRQQLSEQEVRHNREIIELQSKIEK 1150 Query: 1264 FESKYEQL 1271 S QL Sbjct: 1151 APSPELQL 1158 Score = 95.9 bits (228), Expect = 8e-18 Identities = 236/1144 (20%), Positives = 491/1144 (42%), Gaps = 141/1144 (12%) Query: 498 VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEI 557 VK L + + E+I L + +KN++ + +L++ K +++ K+ + ++E Sbjct: 190 VKKLQAENNTMREKIDVLKTNLGEKDKNILTIGQ----ELQEKLKLVEDLEKIKNESREN 245 Query: 558 VRLTEELH-HLSQKVAELEEEKGNLQLHLVDYDSG-RMIE--SDVYKKMIEMENLAETRL 613 V L E+L L +++ + GN+++ + + R+++ S ++ E +A +L Sbjct: 246 VELVEKLKGRLKFYHSKVVKLAGNVKVLKENKNEVLRLLKTYSHQVEEWKEQLGVASKKL 305 Query: 614 -KAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALS 672 + IS ++ Q + +E+ L+ E + QL++ + E KS L E + +S Sbjct: 306 CQEISDIKVQNSEYHKEIEGLK------ESNAKYLKQLEAHKTDDE-KSKELGE-FERIS 357 Query: 673 ASKKELALVIENLKLDKEQL--YGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAE 730 K+ L+ EN +L + QL T++ L +KE ++ L + + + + S + Sbjct: 358 KEHKK--LIEENQRLLQLQLDYQQTVETLTVEKESLLENLSQLEERHQEEIKVFDDQSKK 415 Query: 731 KISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMED 790 E+ +I E+ I+ + I ++ DL + + K S LE S E Sbjct: 416 DTIEIKNRIEENEKICIEYRKVISKLEEDLDLNLRELNDAKQKNYSLQEALEHS---KET 472 Query: 791 RRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQL-----LEIE 845 R ++ ++++ +QE Q E+ +L D+ + VE Q E+E Sbjct: 473 ERQIADKTSEEILKLVQE--------NAQLVEMNRKLQTTRDNCKQVECQTEDSTNSELE 524 Query: 846 HENKELQKKNQILLEE----NQNLQ---ISLSDMQQHYNALVEKANRTDLAESESTKYQT 898 L+++N LL E NQ L+ ++S +Q H +++K + +++ + Sbjct: 525 EVVSGLKRENSELLAEMNEMNQALKERGETISKLQSHCEEVMKKLQLYETQANKNVDNIS 584 Query: 899 Q----LRDLESNLKRI-----THEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEK 949 Q ++ LE ++R+ + + + I K EIE+L+ N+ ++S+ D + ++ Sbjct: 585 QKEEIIKKLEDEIERLKATSDLNSNTSEISDLKNEIENLKERLNSNLDSSYADSECMSTS 644 Query: 950 YEKNIE---YVTQLEAQLQEYKNNIENLNMNVE-ELNKMNLELIDKHVQKQQTQSPDYTE 1005 E + LE +E + NL + ++ ++ ++ EL+ K+Q + D + Sbjct: 645 TISRTEESNRMKDLEGSWEERYGKLRNLAVKLKGKVRDLSNELV-----KEQNEKNDIQQ 699 Query: 1006 QYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQ 1065 + + + + L Q D K+ + + +Y ++L + L + ++ Q Sbjct: 700 KCASNVKTIATLQAQCD--------KLQDELDENKKQIKEYSARL---DSTLAEVSKDKQ 748 Query: 1066 RVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDA 1125 ++S+ NEE+ ++++ +++EL + K+T E + G + ST +A Sbjct: 749 KLSE--------NEEIITILKK---ELEELNQEKVTTEAWKKQISGKV--STFR-KELEA 794 Query: 1126 NNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTEL 1185 N V ++ +E+ ++ S +Q+ L+ + + LN E+ Sbjct: 795 NKVLKKEYEAKIAKLTSDLEAKEQALKAESEYHQQT---KNSLEHSNIERKKNSVLNLEM 851 Query: 1186 TGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGF--EIAELWKQHL 1243 + + + +L KLE+ E + L S + +S+ ++ +Q E AE K + Sbjct: 852 QDY----ERSVKELSQKLEKKQEEINKLKSQLESQKSTTNAVREQNKLLEERAEEMKSEV 907 Query: 1244 AQREADF---QKTEHELRVQLSAFESKYE---QLLDSVQSSTQE---ETNKIVTMEQV-- 1292 +A+ +K +L +S+ E+K Q+L++V+S +E E +K++ Q Sbjct: 908 GATQAEIIACKKQISDLESVMSSKENKIHDLTQILETVRSENEELSTELSKVIAEHQKVN 967 Query: 1293 TSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDL 1352 TSL+++ ++ + + LQ+ DV + +++ E++ + + L Sbjct: 968 TSLKSEKENLKGQILGLQQTLRDVQDALKLKEDELKIVQNDYENYKVRAQSV-------L 1020 Query: 1353 RTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELK 1412 R +NQS E+ ++EE + L V+D + + L H+ Sbjct: 1021 R-QNQSRDVGLEE---KLSEEVSALGVKCEALTAELNKCKTVVDDLKKENEALVHE---- 1072 Query: 1413 DSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHEN--A 1470 SE+ K Y L++ D +++ QL ++ T + SE + LK+H A Sbjct: 1073 KSEVLTK---YEDVLSEVED-LKSLYDQLTNKHQQ----TMIEHSE-TVRSLKVHAETLA 1123 Query: 1471 NHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEE---EVAKTNEMQTALE 1527 Y E E+ + I EL KI ++ S Q+ L EE + N + A+ Sbjct: 1124 QCYRQQLSEQEVRHNREIIELQSKIEKAPSPELQLPPLPMHREEGEGSESTENTSKNAMH 1183 Query: 1528 NQEIEIVTLND---EITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAV 1584 +E + +D EI L+ + SK+ + +DT+Q D MNK L + + Sbjct: 1184 PVPLERLLGSDNDQEIVFLKKQLSEEESKVVHLTALLADTEQ--DLAKHAQMNKLLKEEI 1241 Query: 1585 PRAE 1588 R + Sbjct: 1242 RRQQ 1245 Score = 75.4 bits (177), Expect = 1e-11 Identities = 160/821 (19%), Positives = 340/821 (41%), Gaps = 58/821 (7%) Query: 213 DTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVR-----ISSLEEANKLLEAARFEI 267 + +++ ++N +E + +D L+++ S R ++ + E N+ L+ I Sbjct: 496 EMNRKLQTTRDNCKQVECQTEDSTNSELEEVVSGLKRENSELLAEMNEMNQALKERGETI 555 Query: 268 SLEHSKLAQELEQXXXXXXXXXXXXXXLA-KQSIEPSCEEKTE-IEEKGSLE--IANMTE 323 S S + +++ ++ K+ I E++ E ++ L + +++ Sbjct: 556 SKLQSHCEEVMKKLQLYETQANKNVDNISQKEEIIKKLEDEIERLKATSDLNSNTSEISD 615 Query: 324 LTKKIE-LLEHLNCQIRQTNKELE-NKLATMGTESKAVSSPSKKGSPLISRKSGRNTASK 381 L +IE L E LN + + + E +T+ ++ +GS RN A K Sbjct: 616 LKNEIENLKERLNSNLDSSYADSECMSTSTISRTEESNRMKDLEGSWEERYGKLRNLAVK 675 Query: 382 MKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXX 441 +K LS+E + + +K + + A I +L DK + E D Sbjct: 676 LKGKVRDLSNELVKEQNEKNDIQQKCASNVKTIATLQAQC-DK--LQDELDENKKQIKEY 732 Query: 442 XXGKDTLIAQLQLEHQQHMEGPSLIHV-GTNTEDVNEIAKVQEQLKQELNDEIKDVNVKD 500 D+ +A++ + Q+ E +I + E++N+ E K++++ ++ + Sbjct: 733 SARLDSTLAEVSKDKQKLSENEEIITILKKELEELNQEKVTTEAWKKQISGKVSTFRKEL 792 Query: 501 LIEKL--KSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIV 558 K+ K E +I +L +++A + + H+ ++ + K S N E+ Sbjct: 793 EANKVLKKEYEAKIAKLTSDLEAKEQALKAESEYHQQTKNSLEHSNIERKKNSVLNLEMQ 852 Query: 559 RLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISL 618 + LSQK+ + +EE L+ L +S + + V ++ +E AE + Sbjct: 853 DYERSVKELSQKLEKKQEEINKLKSQL---ESQKSTTNAVREQNKLLEERAEEMKSEVGA 909 Query: 619 LESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKEL 678 +++ +++ L+ E+K+ D++ Q+ ++S + EE LS E Sbjct: 910 TQAEIIACKKQISDLESVMSSKENKIHDLT-----QILETVRSEN-EELSTELSKVIAEH 963 Query: 679 ALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAK 738 V +LK +KE L G I L+ D+ + L+ ++E+ +L K+ + E Sbjct: 964 QKVNTSLKSEKENLKGQILGLQQTLRDVQDALK--LKED-EL--KIVQNDYENYKVRAQS 1018 Query: 739 INHEEQSK-IQTQFGIDAKIQERDLYIENIESELSKYKSRICRL-EESIAVMEDRRYSLE 796 + + QS+ + + + ++ + E + +EL+K K+ + L +E+ A++ ++ L Sbjct: 1019 VLRQNQSRDVGLEEKLSEEVSALGVKCEALTAELNKCKTVVDDLKKENEALVHEKSEVLT 1078 Query: 797 RKADQLGSYLQEKQKAYSEYT-------IQEDELVNRLAVLMDHDRVVEKQLL---EIEH 846 + D L S +++ + Y + T I+ E V L V + +Q L E+ H Sbjct: 1079 KYEDVL-SEVEDLKSLYDQLTNKHQQTMIEHSETVRSLKVHAETLAQCYRQQLSEQEVRH 1137 Query: 847 ENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQL---RDL 903 + ++ +++I + LQ+ M + E T + L D Sbjct: 1138 NREIIELQSKIEKAPSPELQLPPLPMHREEGEGSESTENTSKNAMHPVPLERLLGSDNDQ 1197 Query: 904 E-SNLKRITHEHQTLIVQKKKEIEDLE------IEFNTQIESAIR--DKKVLNEKYEKNI 954 E LK+ E ++ +V + D E + N ++ IR + V EK+ +N+ Sbjct: 1198 EIVFLKKQLSEEESKVVHLTALLADTEQDLAKHAQMNKLLKEEIRRQQRSVEREKHAENL 1257 Query: 955 EYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQK 995 EY+ + + + E + V LN + L+L + QK Sbjct: 1258 EYLKNVVFKFVTLHSGDERSRL-VPVLNTI-LKLSPEETQK 1296 Score = 46.4 bits (105), Expect = 0.007 Identities = 129/597 (21%), Positives = 244/597 (40%), Gaps = 51/597 (8%) Query: 147 LSNTIKEKDNALSVLQVKMKIMETTIL-DLQEKINEKDQIIEAKNKATTXXXXXXXXXXX 205 L + +E+ L L VK+K + +L ++ NEK+ I + K + Sbjct: 658 LEGSWEERYGKLRNLAVKLKGKVRDLSNELVKEQNEKNDI-QQKCASNVKTIATLQAQCD 716 Query: 206 XXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANK---LLEA 262 ++ K+Q+ + + AE +KQ+L ++ E + LEE N+ EA Sbjct: 717 KLQDELDENKKQIKEYSARLDSTLAEVSKDKQKLSENEEIITILKKELEELNQEKVTTEA 776 Query: 263 ARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAK--QSIEPSCEEKTEIEE--KGSLEI 318 + +IS + S +ELE L ++ E + + ++E + K SLE Sbjct: 777 WKKQISGKVSTFRKELEANKVLKKEYEAKIAKLTSDLEAKEQALKAESEYHQQTKNSLEH 836 Query: 319 ANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNT 378 +N+ KK +L ++ KEL KL K +K S L S+KS N Sbjct: 837 SNIER--KKNSVLNLEMQDYERSVKELSQKL------EKKQEEINKLKSQLESQKSTTNA 888 Query: 379 ASK----MKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVD----KEYVISE 430 + ++ ++ SE + K +I+ LE V+ S + D E V SE Sbjct: 889 VREQNKLLEERAEEMKSEVGATQAEIIACKKQISDLESVMSSKENKIHDLTQILETVRSE 948 Query: 431 KDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQE-QLKQEL 489 + + L+ E +++++G ++ + DV + K++E +LK Sbjct: 949 NEELSTELSKVIAEHQKVNTSLKSE-KENLKG-QILGLQQTLRDVQDALKLKEDELKIVQ 1006 Query: 490 ND-EIKDVNVKDLIEKLKSAEEQITQ-LNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNF 547 ND E V + ++ + +S + + + L++E+ A +K ++ +L + + +D+ Sbjct: 1007 NDYENYKVRAQSVLRQNQSRDVGLEEKLSEEVSALG---VKCEA-LTAELNKCKTVVDDL 1062 Query: 548 SKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIE-SDVYKKM-IEM 605 K N+ +V E+ + V E+ +L L + MIE S+ + + + Sbjct: 1063 KK---ENEALVHEKSEVLTKYEDVLSEVEDLKSLYDQLTNKHQQTMIEHSETVRSLKVHA 1119 Query: 606 ENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSE-----IK 660 E LA+ + +S E + + EL +K E +L + + + SE K Sbjct: 1120 ETLAQCYRQQLSEQEVRHNREIIELQSKIEKAPSPELQLPPLPMHREEGEGSESTENTSK 1179 Query: 661 SVHLEEQIDALSASKKELALVIENLKLDKEQ-----LYGTIKDLEND--KEDIMNKL 710 + ++ L S + +V +L +E+ L + D E D K MNKL Sbjct: 1180 NAMHPVPLERLLGSDNDQEIVFLKKQLSEEESKVVHLTALLADTEQDLAKHAQMNKL 1236 >UniRef50_Q23KF2 Cluster: Putative uncharacterized protein; n=1; Tetrahymena thermophila SB210|Rep: Putative uncharacterized protein - Tetrahymena thermophila SB210 Length = 1325 Score = 128 bits (308), Expect = 2e-27 Identities = 180/918 (19%), Positives = 393/918 (42%), Gaps = 62/918 (6%) Query: 480 KVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQ 539 K QE++++ L D + D K+++E +K ++ Q N+ ++ ++ +K + KL LKQ Sbjct: 401 KQQEEIQKLLQDSMND---KEILENMKQQLKKCKQENEMLE--QRDRMKQEDMQKL-LKQ 454 Query: 540 MQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVY 599 + + + S++ + NK ++ E+ L Q+ E + NLQ + +S + ++ Sbjct: 455 LMELSEENSQMRNENKNLIL---EIQELKQQQHEQSQNGVNLQSN----NSYELDQNQNE 507 Query: 600 KKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEI 659 K +N +L Q + + + L K+ + + L S I Sbjct: 508 KSPYSQDNE--------QILNDQAGEDI--ISFLNHKFCNLFYDIEKYQFLDSIYCLPSI 557 Query: 660 KSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNK----LQNYIQ 715 + +E+ I + + E +N D +QL I L+ ++I K L Sbjct: 558 QDKIIEQSIHETNENNSEQINDYQNNNQDNQQLIQQIAGLQQIIDEINQKNLQQLDTINS 617 Query: 716 ENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYK 775 +N L ++L K S ++++ L K + E +Q + I+ +QE + + + E + K Sbjct: 618 QNQQLQEQLTKNS-DQVASLEQKTS--ENKDLQEK--INQLLQEEKNF-DLLTQENKELK 671 Query: 776 SRICRLEESIAVMEDRRYSLERKADQLGSY---LQEKQKAYSEYTIQEDELVNRLAVLMD 832 +I L++ ++ + K D+LG LQE+ + + + ++ N L + Sbjct: 672 QQIQILQQQQEQIQQEQIKNNEKIDELGQKELNLQEQIRQLQQEINELNQKFNNQKQLNE 731 Query: 833 HDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESE 892 ++++ L + E++ +N L E+NQ Q + +QQ N +E N+ + E Sbjct: 732 ESTILQENLQQSLKNIDEIKLENNNLNEQNQQQQEKIKQIQQELNKNIELINQNEKREQN 791 Query: 893 STKYQTQLRDLESNLKRITH-EHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYE 951 Q ++ L+ +K+IT ++Q + ++ D E + N +E + K++ +K + Sbjct: 792 ---LQDEVDQLQQKIKQITDAQNQQNELHLQQSSSDQE-KINNLLEELEKVKELYEQKSK 847 Query: 952 KNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEI 1011 N E + L+ Q+++ + I L + N+ L+ + ++Q + E + ++ Sbjct: 848 DNEEKIEVLQQQVKQKQLEINQLEQQINNKNQEIEALMQQSKEEQIKKLQAQLEDNLQKV 907 Query: 1012 NKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQL 1071 N L + +K + E Q+IN + + + + K + +++ + L Sbjct: 908 NTLQSEIKGLNLETDEQKQQINQFKQKMIELNEILDKK----QVIINQQQQDFNNLKNNL 963 Query: 1072 LDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMII---SSTIEPMSDDANNV 1128 L+ +Q +L+ ++E++D+I +L + N + E + SS + + + Sbjct: 964 LNQEQQANKLEKEIKEKEDKINDLLNQINQAQQNYQEKEENLKQQNSSNQVQLQEYKQQI 1023 Query: 1129 DXXXXXXXXXXXXLKVQEEE-----EFIQERSVLQEQSAKLNTELQECYTKIIQL-ETLN 1182 L Q +E + I + +L EQ+ K + + E K+ L ++ Sbjct: 1024 GMLNQKLISLEQQLSDQIDENQNKQKQIDSQKLLHEQNLKESKKHTENLAKVQNLLDSQI 1083 Query: 1183 TELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQH 1242 E +N +Q +QLKSK Q ++ L + + + + +Q + L +Q Sbjct: 1084 KECKKLKEMNNQQEDQLKSKQNQYEKVSEQLKESEKK-NLDLQNQNEQLISQTNILAQQI 1142 Query: 1243 LAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDK 1302 A+ Q ++ L+VQ ES+ +QL+ + + + Q+ + NK Q+ Sbjct: 1143 QLLNFAENQNSDLNLKVQ--QLESQIQQLIAENNGLNNQNIEQQNQLSQLNNKLNKFQED 1200 Query: 1303 EEHLRNLQEKYADVINQIEILRSEIED---EKVAFXXXXXXXXXXXXXXXXDLRTENQSY 1359 ++ +N Q Y +I ++ R+ I E ++F + ++ Y Sbjct: 1201 NQYFQN-QYTYGQLIQKLLQNRNGISQAMFENISFFMREIHQHIQHQQNNYVIDLYHKVY 1259 Query: 1360 KQMQEQSILNINEENAQL 1377 + ++ +S L N+++ Q+ Sbjct: 1260 QNLESES-LQFNQKSEQI 1276 Score = 124 bits (298), Expect = 3e-26 Identities = 175/922 (18%), Positives = 420/922 (45%), Gaps = 64/922 (6%) Query: 214 TKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSK 273 +KQ + K E I + E ++ ++D+ +K + +E N +L+ ++ IS + + Sbjct: 346 SKQIILKGCEQKIKYLNKQLQESKKKIQDLNNKLNKQEKDKEINSILDPNQY-ISDKQQE 404 Query: 274 LAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEH 333 Q+L Q KQ ++ +E +E++ ++ +M +L K++ L Sbjct: 405 EIQKLLQDSMNDKEILENM----KQQLKKCKQENEMLEQRDRMKQEDMQKLLKQLMELSE 460 Query: 334 LNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGR-NTASKMKSPWSQLSSE 392 N Q+R NK L ++ + + S+ G L S S + KSP+SQ + + Sbjct: 461 ENSQMRNENKNLILEIQELKQQQ---HEQSQNGVNLQSNNSYELDQNQNEKSPYSQDNEQ 517 Query: 393 TLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQL 452 LN E +I LN + Y I EK +D +I Sbjct: 518 ILNDQAG-----------EDIISFLNHKFCNLFYDI-EKYQFLDSIYCLPSIQDKIIE-- 563 Query: 453 QLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDL---IEKLKSAE 509 Q H+ + I+ N N+ Q Q++ DEI N++ L + + + Sbjct: 564 QSIHETNENNSEQINDYQNNNQDNQQLIQQIAGLQQIIDEINQKNLQQLDTINSQNQQLQ 623 Query: 510 EQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQ 569 EQ+T+ +D++ + + + K + K+ Q+ + NF ++ NKE L +++ L Q Sbjct: 624 EQLTKNSDQVASLEQKTSENKDLQE-KINQLLQEEKNFDLLTQENKE---LKQQIQILQQ 679 Query: 570 KVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQE 629 + ++++E+ + + + + +++ + N + L + L + Sbjct: 680 QQEQIQQEQIKNNEKIDELGQKELNLQEQIRQLQQEINELNQKFNNQKQLNEESTILQEN 739 Query: 630 LHILQQKYDEVEDKLADISQLQSDQVCSEIKSV--HLEEQIDALSASKKELALVIENLKL 687 L + DE++ + ++++ Q+ Q +IK + L + I+ ++ ++K +NL+ Sbjct: 740 LQQSLKNIDEIKLENNNLNE-QNQQQQEKIKQIQQELNKNIELINQNEKR----EQNLQD 794 Query: 688 DKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKM--SAEKISELLAKINHEEQS 745 + +QL IK + D ++ N+L ++Q++ +K+ + EK+ EL + + + + Sbjct: 795 EVDQLQQKIKQI-TDAQNQQNEL--HLQQSSSDQEKINNLLEELEKVKELYEQKSKDNEE 851 Query: 746 KIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKAD-QLGS 804 KI+ + +++++ L I +E +++ I L + + ++ + + + Q + Sbjct: 852 KIEV---LQQQVKQKQLEINQLEQQINNKNQEIEALMQQSKEEQIKKLQAQLEDNLQKVN 908 Query: 805 YLQEKQKAYSEYTIQEDELVNRL-AVLMDHDRVVEKQLLEIEHENKELQK-KNQILLEEN 862 LQ + K + T ++ + +N+ +++ + +++K+ + I + ++ KN +L +E Sbjct: 909 TLQSEIKGLNLETDEQKQQINQFKQKMIELNEILDKKQVIINQQQQDFNNLKNNLLNQEQ 968 Query: 863 Q--NLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQ 920 Q L+ + + + N L+ + N+ A+ + + L+ S+ + E++ I Sbjct: 969 QANKLEKEIKEKEDKINDLLNQINQ---AQQNYQEKEENLKQQNSSNQVQLQEYKQQIGM 1025 Query: 921 KKKEIEDLEIEFNTQI-ESAIRDKKVLNEK--YEKNIEYVTQLEAQLQEYKNNIENLNMN 977 +++ LE + + QI E+ + K++ ++K +E+N++ + L + +N +++ Sbjct: 1026 LNQKLISLEQQLSDQIDENQNKQKQIDSQKLLHEQNLKESKKHTENLAKVQNLLDSQIKE 1085 Query: 978 VEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQV 1037 ++L +MN + D+ ++ +Q Q +EQ + E K N L+ ++E++I+ N Sbjct: 1086 CKKLKEMNNQQEDQ-LKSKQNQYEKVSEQ-LKESEKKNLDLQNQNEQLISQ----TNILA 1139 Query: 1038 SYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKE 1097 + +++ E++ + K++ +E ++Q++ + N E Q + + ++++ + +E Sbjct: 1140 QQIQLLNFAENQNSDLNLKVQQLESQIQQLIAENNGLNNQNIEQQNQLSQLNNKLNKFQE 1199 Query: 1098 TKLTFEMNIPKTEGMIISSTIE 1119 F+ T G +I ++ Sbjct: 1200 DNQYFQNQY--TYGQLIQKLLQ 1219 Score = 111 bits (268), Expect = 1e-22 Identities = 201/1022 (19%), Positives = 443/1022 (43%), Gaps = 106/1022 (10%) Query: 632 ILQQKYDEVEDKLADISQLQSDQ-VCSEIKSVHLEEQIDALSASKKELALVIENLKLDKE 690 +L Q + E++ I+ Q Q ++I+ V +Q L+ +K + + E ++ + Sbjct: 206 VLDQANNSDEEQQNKINYYQGTQNSLNQIEKVRKIDQSYHLAINKSKFGEIQEEMESPMK 265 Query: 691 QLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLE---KMSAEKISELLAKINHEEQSKI 747 + +G+ N ++ I+NK N + + D+ E ++ EK EL+ +N+ + K+ Sbjct: 266 EDFGS-----NIQKAIINKNDNLNTDYFNQNDQQEGQFNINLEKQKELIQDLNNLD--KL 318 Query: 748 QTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQ 807 + Q + L+ +NIE +L K + + +++ E+K L LQ Sbjct: 319 TSD-------QIKKLF-KNIEEQLHCLKFCYQQNQSKQIILK----GCEQKIKYLNKQLQ 366 Query: 808 EKQKAYSEYT--IQEDELVNRLAVLMDHDRVV-EKQLLEIEHENKELQKKNQILLEENQN 864 E +K + + + E + ++D ++ + +KQ EI+ ++ +IL +N Sbjct: 367 ESKKKIQDLNNKLNKQEKDKEINSILDPNQYISDKQQEEIQKLLQDSMNDKEIL----EN 422 Query: 865 LQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQ---- 920 ++ L +Q N ++E+ +R + + + K QL +L ++ +E++ LI++ Sbjct: 423 MKQQLKKCKQE-NEMLEQRDR--MKQEDMQKLLKQLMELSEENSQMRNENKNLILEIQEL 479 Query: 921 KKKEIEDLEIEFNTQIESAIRDKKVLNEK--YEKNIEYVTQLEA--QLQEYKNN-IENLN 975 K+++ E + N Q ++ + NEK Y ++ E + +A + + N+ NL Sbjct: 480 KQQQHEQSQNGVNLQSNNSYELDQNQNEKSPYSQDNEQILNDQAGEDIISFLNHKFCNLF 539 Query: 976 MNVEELNKMNL-----ELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQ 1030 ++E+ ++ + DK +++ ++ + + IN+ N +Q ++I L Q Sbjct: 540 YDIEKYQFLDSIYCLPSIQDKIIEQSIHETNENNSEQINDYQNNNQDNQQLIQQIAGLQQ 599 Query: 1031 KINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQ-- 1088 I+ + + S+ Q +L +++ + ++ ++K E++ L++E+ Sbjct: 600 IIDEINQKNLQQLDTINSQNQQLQEQLTKNSDQVASLEQKTSENKDLQEKINQLLQEEKN 659 Query: 1089 -DDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEE 1147 D +E KE K ++ + E + D ++ E Sbjct: 660 FDLLTQENKELKQQIQILQQQQEQIQQEQIKNNEKIDELGQKELNLQEQIRQLQQEINEL 719 Query: 1148 EEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLE--- 1204 + + L E+S L LQ+ I +++ N L + QE+I Q++ +L Sbjct: 720 NQKFNNQKQLNEESTILQENLQQSLKNIDEIKLENNNLNEQNQQQQEKIKQIQQELNKNI 779 Query: 1205 QLNTEND----NLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEH---EL 1257 +L +N+ NL V +L+ I D + + EL HL Q +D +K + EL Sbjct: 780 ELINQNEKREQNLQDEVDQLQQKIKQITDAQNQQ-NEL---HLQQSSSDQEKINNLLEEL 835 Query: 1258 RVQLSAFESKY---EQLLDSVQSSTQEETNKIVTMEQVTSLQNK------LQDKEEHLRN 1308 +E K E+ ++ +Q +++ +I +EQ + +N+ Q KEE ++ Sbjct: 836 EKVKELYEQKSKDNEEKIEVLQQQVKQKQLEINQLEQQINNKNQEIEALMQQSKEEQIKK 895 Query: 1309 LQEKYADVINQIEILRSEIE------DEKVA----FXXXXXXXXXXXXXXXXDLRTENQS 1358 LQ + D + ++ L+SEI+ DE+ F + + Q Sbjct: 896 LQAQLEDNLQKVNTLQSEIKGLNLETDEQKQQINQFKQKMIELNEILDKKQVIINQQQQD 955 Query: 1359 YKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQ 1418 + ++ ++LN ++ +L+K ++N A+ E L+ ++S Sbjct: 956 FNNLKN-NLLNQEQQANKLEKEIKEKEDKINDLLNQINQAQQNYQEKEENLKQQNSSNQV 1014 Query: 1419 KTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQK 1478 + EY + N + ++ QQL + ++ + +S+ + + E+ H E + K Sbjct: 1015 QLQEYKQQIGMLNQKLISLEQQLSDQIDENQNKQKQIDSQKLLHEQNLKESKKHTENLAK 1074 Query: 1479 -----ESEIERVKLIEELNVKITESV-SLNKQVAELNKALEEEVAKT------NEM---Q 1523 +S+I+ K ++E+N + + + S Q ++++ L+E K NE Q Sbjct: 1075 VQNLLDSQIKECKKLKEMNNQQEDQLKSKQNQYEKVSEQLKESEKKNLDLQNQNEQLISQ 1134 Query: 1524 TALENQEIEIVTL-NDEITNLQNMVRASSSKIQKHVSFASD------TKQGRDEQLDNTM 1576 T + Q+I+++ ++ ++L V+ S+IQ+ ++ + +Q + QL+N + Sbjct: 1135 TNILAQQIQLLNFAENQNSDLNLKVQQLESQIQQLIAENNGLNNQNIEQQNQLSQLNNKL 1194 Query: 1577 NK 1578 NK Sbjct: 1195 NK 1196 Score = 102 bits (245), Expect = 7e-20 Identities = 171/884 (19%), Positives = 389/884 (44%), Gaps = 74/884 (8%) Query: 331 LEHLNCQIRQTNKELENKLATMGTESKAVSSPS-KKGSPLISRKSGRNTASKMKSPWSQL 389 +++LN Q++++ K++++ + + K S + IS K ++ + Sbjct: 358 IKYLNKQLQESKKKIQDLNNKLNKQEKDKEINSILDPNQYISDKQQEEIQKLLQDSMNDK 417 Query: 390 SS-ETLNQDTDKKINKNE-IAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDT 447 E + Q K +NE + + + + Q + L+ + +SE+++ K+ Sbjct: 418 EILENMKQQLKKCKQENEMLEQRDRMKQEDMQKLLKQLMELSEENSQMRNE-----NKNL 472 Query: 448 LIAQLQLEHQQHMEGPSLIHVGTNT-----EDVNEIAKVQEQLKQELNDEIKDVNVKDLI 502 ++ +L+ QQH + + +++ +N ++ NE + + +Q LND+ + + L Sbjct: 473 ILEIQELKQQQHEQSQNGVNLQSNNSYELDQNQNEKSPYSQDNEQILNDQAGEDIISFLN 532 Query: 503 EKLKSAEEQIT--QLNDEIDAANKNMIKV--KSNHKLKLKQMQKTIDNFSKVSDSNKEIV 558 K + I Q D I K+ +S H+ ++ I+++ + N++++ Sbjct: 533 HKFCNLFYDIEKYQFLDSIYCLPSIQDKIIEQSIHETNENNSEQ-INDYQNNNQDNQQLI 591 Query: 559 RLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISL 618 +++ L Q + E+ ++ NLQ + ++ + K ++ +L + + L Sbjct: 592 ---QQIAGLQQIIDEINQK--NLQQLDTINSQNQQLQEQLTKNSDQVASLEQKTSENKDL 646 Query: 619 LE--SQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKK 676 E +Q + +L Q+ E++ ++ I Q Q +Q+ E + E+ID L +K Sbjct: 647 QEKINQLLQEEKNFDLLTQENKELKQQI-QILQQQQEQIQQE--QIKNNEKIDELG--QK 701 Query: 677 ELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDK-LEKMSAEKISEL 735 EL L E ++ ++++ + N K+ +N+ +QEN+ + K ++++ E + Sbjct: 702 ELNLQ-EQIRQLQQEINELNQKFNNQKQ--LNEESTILQENLQQSLKNIDEIKLENNN-- 756 Query: 736 LAKINHEEQSKI-QTQFGIDAKIQ---ERDLYIENIESELSKYKSRICRLEESIAVMEDR 791 L + N ++Q KI Q Q ++ I+ + + +N++ E+ + + +I ++ ++ ++ Sbjct: 757 LNEQNQQQQEKIKQIQQELNKNIELINQNEKREQNLQDEVDQLQQKIKQITDA-QNQQNE 815 Query: 792 RYSLERKADQ--LGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQL------LE 843 + + +DQ + + L+E +K Y + + ++ VL +V +KQL + Sbjct: 816 LHLQQSSSDQEKINNLLEELEKVKELYEQKSKDNEEKIEVLQQ--QVKQKQLEINQLEQQ 873 Query: 844 IEHENKELQKKNQILLEEN-QNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRD 902 I ++N+E++ Q EE + LQ L D Q N L + +L E + Q + Sbjct: 874 INNKNQEIEALMQQSKEEQIKKLQAQLEDNLQKVNTLQSEIKGLNLETDEQKQQINQFKQ 933 Query: 903 LESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEA 962 L I + Q +I Q++++ +L+ Q + A + +K + EK +K + + Q+ Sbjct: 934 KMIELNEILDKKQVIINQQQQDFNNLKNNLLNQEQQANKLEKEIKEKEDKINDLLNQINQ 993 Query: 963 QLQEYKNNIENL----NMNVEELN--KMNLELIDKHVQKQQTQSPDYTEQYINE------ 1010 Q Y+ ENL + N +L K + ++++ + + Q D ++ N+ Sbjct: 994 AQQNYQEKEENLKQQNSSNQVQLQEYKQQIGMLNQKLISLEQQLSDQIDENQNKQKQIDS 1053 Query: 1011 ---INKLNALLKQKDEEIIALNQKINNAQV----SYMSMVSDYESKLAQFTTKLENMEEE 1063 +++ N +K E +A Q + ++Q+ M + E +L + E + E+ Sbjct: 1054 QKLLHEQNLKESKKHTENLAKVQNLLDSQIKECKKLKEMNNQQEDQLKSKQNQYEKVSEQ 1113 Query: 1064 MQRVSKQLLDSKQHNEEL--QILVREQDDQIKELKETKLT-FEMNIPKTEGMIISSTIEP 1120 ++ K+ LD + NE+L Q + Q Q+ E + + + + + E I E Sbjct: 1114 LKESEKKNLDLQNQNEQLISQTNILAQQIQLLNFAENQNSDLNLKVQQLESQIQQLIAEN 1173 Query: 1121 MSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKL 1164 + N++ K QE+ ++ Q + + KL Sbjct: 1174 NGLNNQNIEQQNQLSQLNNKLNKFQEDNQYFQNQYTYGQLIQKL 1217 Score = 99 bits (238), Expect = 5e-19 Identities = 182/952 (19%), Positives = 405/952 (42%), Gaps = 89/952 (9%) Query: 701 NDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISE---LLAKINH---EEQSKIQTQFGID 754 ++K D +NK + + E D D + ++ +E +L + N+ E+Q+KI G Sbjct: 169 SNKNDQLNKSAHQVIEEQDQNDHFSEQEQDEYNENGDVLDQANNSDEEQQNKINYYQGTQ 228 Query: 755 AKIQERDLYIENIES-ELSKYKSRICRLEESI--AVMEDRRYSLER----KADQLGS-YL 806 + + + + +S L+ KS+ ++E + + ED ++++ K D L + Y Sbjct: 229 NSLNQIEKVRKIDQSYHLAINKSKFGEIQEEMESPMKEDFGSNIQKAIINKNDNLNTDYF 288 Query: 807 QEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQ 866 + + ++ I ++ + L + D++ Q+ ++ +E + ++NQ+ Q Sbjct: 289 NQNDQQEGQFNINLEKQKELIQDLNNLDKLTSDQIKKLFKNIEEQLHCLKFCYQQNQSKQ 348 Query: 867 ISLSDMQQHYNALVEKANRT-DLAESESTKYQTQLRDLESNL----KRITHEHQTLIVQK 921 I L +Q L ++ + + + K Q +D E N + + Q +QK Sbjct: 349 IILKGCEQKIKYLNKQLQESKKKIQDLNNKLNKQEKDKEINSILDPNQYISDKQQEEIQK 408 Query: 922 --KKEIEDLEI--EFNTQIESAIRDKKVL-------NEKYEKNIEYVTQLEAQLQEYKNN 970 + + D EI Q++ ++ ++L E +K ++ + +L + + +N Sbjct: 409 LLQDSMNDKEILENMKQQLKKCKQENEMLEQRDRMKQEDMQKLLKQLMELSEENSQMRNE 468 Query: 971 IENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLN-----ALLKQKDEEI 1025 +NL + ++EL + E V Q S + +Q NE + + L Q E+I Sbjct: 469 NKNLILEIQELKQQQHEQSQNGVNLQSNNSYE-LDQNQNEKSPYSQDNEQILNDQAGEDI 527 Query: 1026 IA-LNQKINNAQV---SYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEEL 1081 I+ LN K N Y + S Y Q +++ E + S+Q+ D + +N++ Sbjct: 528 ISFLNHKFCNLFYDIEKYQFLDSIYCLPSIQDKIIEQSIHETNENNSEQINDYQNNNQDN 587 Query: 1082 QILVRE---QDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXX 1138 Q L+++ I E+ + L +++ ++ + + SD +++ Sbjct: 588 QQLIQQIAGLQQIIDEINQKNLQ-QLDTINSQNQQLQEQLTKNSDQVASLEQKTSENKDL 646 Query: 1139 XXXLK--VQEEEEF---IQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQ 1193 + +QEE+ F QE L++Q L + ++ + I+ EL ++ Q Sbjct: 647 QEKINQLLQEEKNFDLLTQENKELKQQIQILQQQQEQIQQEQIKNNEKIDELGQKELNLQ 706 Query: 1194 EQINQLKSKLEQLNTENDNLL-----STVAE--LRSSISSAVDQRGFEIAELWKQHLAQR 1246 EQI QL+ ++ +LN + +N ST+ + L+ S+ + +D+ E L +Q+ Q+ Sbjct: 707 EQIRQLQQEINELNQKFNNQKQLNEESTILQENLQQSLKN-IDEIKLENNNLNEQNQQQQ 765 Query: 1247 EADFQ-KTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKI---------VTMEQVTSLQ 1296 E Q + E ++L K EQ L Q++ +I + ++Q +S Q Sbjct: 766 EKIKQIQQELNKNIELINQNEKREQNLQDEVDQLQQKIKQITDAQNQQNELHLQQSSSDQ 825 Query: 1297 NKLQDKEEHLRNLQEKY----ADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDL 1352 K+ + E L ++E Y D +IE+L+ +++ +++ + Sbjct: 826 EKINNLLEELEKVKELYEQKSKDNEEKIEVLQQQVKQKQLEINQLEQQINNKNQEIEALM 885 Query: 1353 -RTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLEL 1411 +++ + K++Q Q N+ + N L+ ++N + K++EL L+ Sbjct: 886 QQSKEEQIKKLQAQLEDNLQKVNT-LQSEIKGLNLETDEQKQQINQFKQKMIELNEILDK 944 Query: 1412 KDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYE-KESELAILRLKMHENA 1470 K + + Q+ +F N++ L+ E++ L E KE E I L N Sbjct: 945 KQ-----------VIINQQQQDFNNLKNNLLNQEQQANKLEKEIKEKEDKINDLLNQINQ 993 Query: 1471 NHYETMQKESEIERVKLIEELNV-KITESVS-LNKQVAELNKALEEEVAKTNEMQTALEN 1528 +KE +++ ++ + + + + LN+++ L + L +++ + Q +++ Sbjct: 994 AQQNYQEKEENLKQQNSSNQVQLQEYKQQIGMLNQKLISLEQQLSDQIDENQNKQKQIDS 1053 Query: 1529 QE-IEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKE 1579 Q+ + L + + +N+ + + + + K+ ++Q D +K+ Sbjct: 1054 QKLLHEQNLKESKKHTENLAKV-QNLLDSQIKECKKLKEMNNQQEDQLKSKQ 1104 Score = 37.9 bits (84), Expect = 2.3 Identities = 76/424 (17%), Positives = 177/424 (41%), Gaps = 37/424 (8%) Query: 152 KEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXX 211 K+ + + VLQ ++K + I L+++IN K+Q IEA + + Sbjct: 847 KDNEEKIEVLQQQVKQKQLEINQLEQQINNKNQEIEALMQQS------KEEQIKKLQAQL 900 Query: 212 EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISS-LEEANKLLEAARFEIS-- 268 ED Q++ +Q + E ++KQ+ + + K + ++ L++ ++ + + + Sbjct: 901 EDNLQKVNTLQSEIKGLNLETDEQKQQ-INQFKQKMIELNEILDKKQVIINQQQQDFNNL 959 Query: 269 ----LEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTEL 324 L + A +LE+ Q+ + E++ ++++ S + E Sbjct: 960 KNNLLNQEQQANKLEKEIKEKEDKINDLLNQINQAQQNYQEKEENLKQQNSSNQVQLQEY 1019 Query: 325 TKKIELLEH----LNCQIRQTNKELENKLATMGTES---KAVSSPSKKGSPLISR----- 372 ++I +L L Q+ E +NK + ++ + SKK + +++ Sbjct: 1020 KQQIGMLNQKLISLEQQLSDQIDENQNKQKQIDSQKLLHEQNLKESKKHTENLAKVQNLL 1079 Query: 373 KSGRNTASKMKSPWSQLSSETLN-QDTDKKINK--NEIAKLEMVIQSLNKDLVDKEYVIS 429 S K+K +Q + + Q+ +K+++ E K + +Q+ N+ L+ + +++ Sbjct: 1080 DSQIKECKKLKEMNNQQEDQLKSKQNQYEKVSEQLKESEKKNLDLQNQNEQLISQTNILA 1139 Query: 430 EKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLK--Q 487 ++ + + QL+ + QQ + + ++ N E N+++++ +L Q Sbjct: 1140 QQIQLLNFAENQNSDLNLKVQQLESQIQQLIAENNGLN-NQNIEQQNQLSQLNNKLNKFQ 1198 Query: 488 ELNDEIKD-VNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDN 546 E N ++ LI+KL I+Q E N + + + ++ +Q ID Sbjct: 1199 EDNQYFQNQYTYGQLIQKLLQNRNGISQAMFE----NISFFMREIHQHIQHQQNNYVIDL 1254 Query: 547 FSKV 550 + KV Sbjct: 1255 YHKV 1258 >UniRef50_Q16FM5 Cluster: LL5 beta protein, putative; n=2; Aedes aegypti|Rep: LL5 beta protein, putative - Aedes aegypti (Yellowfever mosquito) Length = 2242 Score = 128 bits (308), Expect = 2e-27 Identities = 269/1439 (18%), Positives = 570/1439 (39%), Gaps = 115/1439 (7%) Query: 212 EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271 E KQ + Q A++ + +K+ LLK I KD +L + N L + EH Sbjct: 549 ELVKQTANEYQRKNQALDEDVNRQKRDLLKLISEKD----ALSQQNLTLNVEFNSLKGEH 604 Query: 272 SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEE--KTEIEEKGSLEIANMTELTKKIE 329 L +++ + +E +T E+K L NM +K+ Sbjct: 605 ESLTAKIDYLMLSLNEDYEGSDFSSWFDKMDDLKERVRTLKEDKERLTGMNMKITMEKVG 664 Query: 330 LLEHLNC------QIRQTNKELENKLATMGTE-SKAVSSPSKKGSPLISRKSGRNTASKM 382 L +H++ ++++ + E E KL + + S++ + +KG+ + S + + + Sbjct: 665 LEKHISVSEMRLKEMKELHAESEKKLRRLSEQLSESEKALEEKGNCVTSLE---KLKADL 721 Query: 383 KSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVIS-EKDTXXXXXXXX 441 + LS+E L + + E ++S+ +L ++ +S K+T Sbjct: 722 EENIQGLSAELLESQSKLNEMSEDFQSCEETLRSVRDELESRDQELSCAKNTIEELQTNL 781 Query: 442 XXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDL 501 + L + +QL+ + E L N DV + + ++ QE +++ VN++ Sbjct: 782 EKQQVELQSAMQLQQETASEKEQL---AVNLTDVQQKLSEESEILQETIKKLEQVNLE-- 836 Query: 502 IEKLKSAEEQITQ--------LNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDS 553 +KL + + Q L ++ + KN K N +L+L+ +Q+ + N + S Sbjct: 837 WQKLTEHRDNLQQDKLILEEALAEQCNELGKNS-KTIQNLELQLQNLQQLLANEADQSKE 895 Query: 554 NKEIV--RLTEELHHL--SQKVAELEEEKGNLQLHLVDYDSGRM--IESDVYKKMIEME- 606 ++ + ++ + H L S+K + L ++ G++ +E K+ +E Sbjct: 896 TQQSLNAQIINQQHQLDASRKEQHILSAANRSLLTGLELVQGKITQLEGQYVSKIGTLEA 955 Query: 607 NLAE-----TRLKAISL--------LESQKFDLVQELHILQQKYD---EVEDKLAD-ISQ 649 L E T+L A LE +++E ILQ + D EVE+ L + + Sbjct: 956 KLGEFAALLTKLSAYQFKLRLEKAQLEDNLGKMIREFEILQTENDKLLEVENALQQTVQE 1015 Query: 650 LQSDQVCSEIKSVHLEEQ-------IDALSASKKELALVIENLKLDKEQLYG----TIKD 698 L+ ++ E +SV LEEQ +D KEL L+ ++ +L G K+ Sbjct: 1016 LRLEKTAVEERSVGLEEQLAEMEVRVDLNGNRIKELEGSCAELEAERTRLLGDGSQREKE 1075 Query: 699 LENDKEDI---MNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQ-TQFGID 754 L+ E+ KL+ I++ L+ EK+ + N ++ +++ + +D Sbjct: 1076 LQKQIEEAAAGSEKLEQEIKQMNKAQSDLQAQLIEKLEQFKCVSNERDEMEVKCARLEVD 1135 Query: 755 AKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYS 814 K + DL E S +++ LE + + + LE+ ++ L++ + Sbjct: 1136 MKELQADLE-EQKHMTTSNCEAK-AALEAQLLAVREELSQLEQDKSRVEETLEKNRATLE 1193 Query: 815 EYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQ 874 E T L +L + + + L + +Q+K + E++ L L D+ Sbjct: 1194 ERTETISRLSREKELLSEKVQELATVLATVRQTKSTIQQKLEEQQEKSDELSCQLEDLNS 1253 Query: 875 HYNALVEKANR-TDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFN 933 A+ E+ R T+ E+ + + ++L ++ +T E + + + + + + Sbjct: 1254 KLLAVAEELGRVTEEKEAILIRQNAEKQELVEKVEELT-ESIAMAEEDRDTLREEKCRLQ 1312 Query: 934 TQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHV 993 ++E DK L+E+ K ++ QL + ++ N + + L + ++ Sbjct: 1313 AEVERIEHDKGSLDEQCGKLLK---QLSKEREDAANEKARQEITIAALGE------ERDA 1363 Query: 994 QKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQK--INNAQVSYMSMVSDYESKLA 1051 +++ + D E+ K+ L + K AL+ K + + V ++ + S+ Sbjct: 1364 LQEKLAAID--EERGALAGKVAELEETKTGLECALSDKGAVESKVVELSKLIDELRSEKM 1421 Query: 1052 QFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEG 1111 + + ++ EE+ +K + + K++ L+ + Q+ ET + Sbjct: 1422 KLEGEWSSLSEELHSNNKTIEELKENVRTLEESKKNLQSQVSNGNETNKQLRQEVQDLSK 1481 Query: 1112 MIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQE-EEEFIQERSVLQEQSAKLNTELQE 1170 + +S E +A V+ KV+E E Q S LQE A L T+ +E Sbjct: 1482 ALQASKQE---IEAMEVETKKLATELTQSEAKVEELSAEIKQTSSQLQEVEAILKTKERE 1538 Query: 1171 CYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQ 1230 +L +L ++ I Q +E + TE L + ++ + S+ Sbjct: 1539 SAVVSEKLVERTKDLELVRSQKEDVILQQSRNIESIQTEQQELAKRLQQVLTESSN---- 1594 Query: 1231 RGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTME 1290 R E+ +L + L R + + E E+ + S E L S + + N ++ Sbjct: 1595 REAEVKQLTGE-LNSRSLELKAKEQEVHAKEQEIRSATELLTASEAKAAELSLN----VD 1649 Query: 1291 QVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXX 1350 Q+ + ++ L E +R LQ+ + + + ED A Sbjct: 1650 QLNAAKSSL---EMQIRKLQDDFDHERELCQATERKAED-LAASLSEASESKIRLEHQLH 1705 Query: 1351 DLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLE 1410 L E + + +Q I +++ AQ+ K E KV + LE Sbjct: 1706 QLEIERTNAESANQQLIQQLSDLKAQVAKQQTSIDAKDTEIHHLTEGLE-KVKRIQSHLE 1764 Query: 1411 LKDSE---IYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKE--SELAILRLK 1465 K ++ + + E L + +E E ++ E ++ + EK I +L+ Sbjct: 1765 EKVTDFESVVTEKDEIETQLIRLQNELETIQDDKRRIETELDAVKEEKADVDRRLIQQLQ 1824 Query: 1466 MHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTA 1525 ++ N ++E+ E + LN K+ E+ + N + +++ + ++A E + A Sbjct: 1825 NYDTVNEAYRNEREANKELQAKQQNLNKKLQEATAENALLVHTHESSKAQLA-AKEKRIA 1883 Query: 1526 LENQEIEIVTLNDEITNL--QNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLD 1582 +++++E L E+ NL +N S + H+ + + E+L+ + ++ ++ Sbjct: 1884 EQDKQME--KLKREMENLFGKNQQMDSLASEFMHLKVEKSELEAKKEELNEAIEQKEIE 1940 Score = 127 bits (306), Expect = 3e-27 Identities = 283/1448 (19%), Positives = 591/1448 (40%), Gaps = 126/1448 (8%) Query: 169 ETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAM 228 E + L E+++E ++ +E K T + + +K+ E ++ Sbjct: 687 EKKLRRLSEQLSESEKALEEKGNCVTSLEKLKADLEENIQGLSAELLESQSKLNE--MSE 744 Query: 229 EAEWKDEKQRLLKD-IESKDVRIS----SLEEANKLLEAARFEISLEHSKLAQELEQXXX 283 + + +E R ++D +ES+D +S ++EE LE + E+ + A +L+Q Sbjct: 745 DFQSCEETLRSVRDELESRDQELSCAKNTIEELQTNLEKQQVEL-----QSAMQLQQETA 799 Query: 284 XXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNK 343 +Q + E E +K LE N+ E K E ++L + Sbjct: 800 SEKEQLAVNLTDVQQKLSEESEILQETIKK--LEQVNL-EWQKLTEHRDNLQQDKLILEE 856 Query: 344 ELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKIN 403 L + +G SK + + + L ++ N A + K L+++ +NQ + Sbjct: 857 ALAEQCNELGKNSKTIQNLELQLQNL--QQLLANEADQSKETQQSLNAQIINQQHQLDAS 914 Query: 404 KNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGP 463 + E + ++ + N+ L+ ++ K T G TL A+L E + Sbjct: 915 RKE----QHILSAANRSLLTGLELVQGKITQLEGQYVSKIG--TLEAKLG-EFAALLTKL 967 Query: 464 SLIHVGTNTEDVNEIAKVQEQLKQELND-EIKDVNVKDLIEKLKSAEEQITQLNDEIDAA 522 S E A++++ L + + + EI L+E + ++ + +L E A Sbjct: 968 SAYQFKLRLEK----AQLEDNLGKMIREFEILQTENDKLLEVENALQQTVQELRLEKTAV 1023 Query: 523 NKNMIKVKSNHKLKLKQMQKTID-NFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNL 581 + + ++ +L +M+ +D N +++ + L E L ++ E+E L Sbjct: 1024 EERSVGLEE----QLAEMEVRVDLNGNRIKELEGSCAELEAERTRLLGDGSQREKE---L 1076 Query: 582 QLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVE 641 Q + + +G S+ ++ I+ N KA S L++Q + +++ + + DE+E Sbjct: 1077 QKQIEEAAAG----SEKLEQEIKQMN------KAQSDLQAQLIEKLEQFKCVSNERDEME 1126 Query: 642 DKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLEN 701 K A +L+ D E+++ LEEQ +++ + A + L +E+L LE Sbjct: 1127 VKCA---RLEVDM--KELQA-DLEEQKHMTTSNCEAKAALEAQLLAVREEL----SQLEQ 1176 Query: 702 DKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERD 761 DK + L+ + T+ + ++S EK ELL++ E + + T + IQ++ Sbjct: 1177 DKSRVEETLEKNRATLEERTETISRLSREK--ELLSEKVQELATVLATVRQTKSTIQQK- 1233 Query: 762 LYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQED 821 +E + K C+LE D L A++LG +EK+ ++ Sbjct: 1234 -----LEEQQEKSDELSCQLE-------DLNSKLLAVAEELGRVTEEKEAILIRQNAEKQ 1281 Query: 822 ELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVE 881 ELV ++ L + + E+ + E LQ + + + + +L + + + E Sbjct: 1282 ELVEKVEELTESIAMAEEDRDTLREEKCRLQAEVERIEHDKGSLDEQCGKLLKQLSKERE 1341 Query: 882 KANRTDLAESESTKYQTQLRD-LESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAI 940 A + + + RD L+ L I E L K E+E E T +E A+ Sbjct: 1342 DAANEKARQEITIAALGEERDALQEKLAAIDEERGAL-AGKVAELE----ETKTGLECAL 1396 Query: 941 RDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQS 1000 DK + K + + + +L ++ + + +L+ + NK +E + ++V+ + Sbjct: 1397 SDKGAVESKVVELSKLIDELRSEKMKLEGEWSSLSEELHSNNK-TIEELKENVRTLEESK 1455 Query: 1001 PDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSM-VSDYESKLAQFTTKLEN 1059 + Q N N+ N L+Q+ +++ Q + ++ M + ++L Q K+E Sbjct: 1456 KNLQSQVSNG-NETNKQLRQEVQDLSKALQA-SKQEIEAMEVETKKLATELTQSEAKVEE 1513 Query: 1060 MEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMII--SST 1117 + E+++ S QL ++ L+ RE ++L E E+ + E +I+ S Sbjct: 1514 LSAEIKQTSSQL---QEVEAILKTKERESAVVSEKLVERTKDLELVRSQKEDVILQQSRN 1570 Query: 1118 IEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQ 1177 IE + + + E E Q L +S +L + QE + K + Sbjct: 1571 IESIQTEQQELAKRLQQVLTESS----NREAEVKQLTGELNSRSLELKAKEQEVHAKEQE 1626 Query: 1178 LETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAE 1237 + + LT ++ + +L ++QLN +L + +L+ ++ + E Sbjct: 1627 IRSATELLTA----SEAKAAELSLNVDQLNAAKSSLEMQIRKLQDDFDH--ERELCQATE 1680 Query: 1238 LWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTME-QVTSLQ 1296 + LA ++ +++ L QL E + + +S+ Q+ ++ ++ QV Q Sbjct: 1681 RKAEDLAASLSEASESKIRLEHQLHQLEIERT----NAESANQQLIQQLSDLKAQVAKQQ 1736 Query: 1297 NKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTEN 1356 + K+ + +L E + +++ ++S +E EKV L+ E Sbjct: 1737 TSIDAKDTEIHHLTEG----LEKVKRIQSHLE-EKVTDFESVVTEKDEIETQLIRLQNEL 1791 Query: 1357 QSY---KQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKD 1413 ++ K+ E + + EE A + + VN+A E +L+ K Sbjct: 1792 ETIQDDKRRIETELDAVKEEKADVDRRLIQQLQNYDT----VNEAYRNEREANKELQAKQ 1847 Query: 1414 SEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHY 1473 + +K E T E+ + QL EKRI E++ ++ L+ +M EN Sbjct: 1848 QNLNKKLQEATAENALLVHTHESSKAQLAAKEKRIA----EQDKQMEKLKREM-ENL--- 1899 Query: 1474 ETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEI 1533 K +++ + E +++K+ +S L + ELN+A+E++ + MQ ++E+ + + Sbjct: 1900 --FGKNQQMDSLAS-EFMHLKVEKS-ELEAKKEELNEAIEQKEIEEKAMQESMEHLKESL 1955 Query: 1534 VTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDLAM 1593 E+ +L + V + S K + QL +N EL +A +++ Sbjct: 1956 KVKQQELDSLHSDVTNLKESLHSLKIENSKLKSTHELQLTKMLNLELKNAEQSKKIEKLE 2015 Query: 1594 YMLHQRDV 1601 L++ ++ Sbjct: 2016 ESLNKTEI 2023 Score = 121 bits (292), Expect = 1e-25 Identities = 232/1174 (19%), Positives = 477/1174 (40%), Gaps = 89/1174 (7%) Query: 473 EDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSN 532 E V + A ++ Q L++++ +DL+ KL S ++ ++Q N ++ ++ + Sbjct: 549 ELVKQTANEYQRKNQALDEDVNRQK-RDLL-KLISEKDALSQQNLTLNVEFNSLKGEHES 606 Query: 533 HKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGR 592 K+ + +++ + SD + +++ L ++V L+E+K L +G Sbjct: 607 LTAKIDYLMLSLNEDYEGSDFSSWF----DKMDDLKERVRTLKEDKERL--------TGM 654 Query: 593 MIESDVYKKMIEME-NLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQ 651 ++ + K +E +++E RLK + L ++ ++L L ++ E E L + Sbjct: 655 NMKITMEKVGLEKHISVSEMRLKEMKELHAES---EKKLRRLSEQLSESEKALEEKGNCV 711 Query: 652 SDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQ 711 + ++K+ LEE I LSA E + + D + T++ + ++ E +L Sbjct: 712 TS--LEKLKA-DLEENIQGLSAELLESQSKLNEMSEDFQSCEETLRSVRDELESRDQELS 768 Query: 712 NYIQENMDLTDKLEKMSAEKIS--ELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIES 769 +L LEK E S +L + E++ + K+ E ++ Sbjct: 769 CAKNTIEELQTNLEKQQVELQSAMQLQQETASEKEQLAVNLTDVQQKLSEESEILQETIK 828 Query: 770 ELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAV 829 +L + +L E ++ + LE + + L + K +Q L LA Sbjct: 829 KLEQVNLEWQKLTEHRDNLQQDKLILEEALAEQCNELGKNSKTIQNLELQLQNLQQLLAN 888 Query: 830 LMDHDRVVEK----QLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNAL----VE 881 D + ++ Q++ +H+ +K+ IL N++L L +Q L V Sbjct: 889 EADQSKETQQSLNAQIINQQHQLDASRKEQHILSAANRSLLTGLELVQGKITQLEGQYVS 948 Query: 882 KANRTD--LAE-----SESTKYQTQLR----DLESNLKRITHEHQTLIVQKKKEIEDLEI 930 K + L E ++ + YQ +LR LE NL ++ E + L + K +E +E Sbjct: 949 KIGTLEAKLGEFAALLTKLSAYQFKLRLEKAQLEDNLGKMIREFEILQTENDKLLE-VEN 1007 Query: 931 EFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELI- 989 ++ +K + E+ E + ++E ++ N I+ L + EL L+ Sbjct: 1008 ALQQTVQELRLEKTAVEERSVGLEEQLAEMEVRVDLNGNRIKELEGSCAELEAERTRLLG 1067 Query: 990 -----DKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVS 1044 +K +QKQ ++ +E+ EI ++N ++I +K+ Q +S Sbjct: 1068 DGSQREKELQKQIEEAAAGSEKLEQEIKQMNKAQSDLQAQLI---EKLE--QFKCVSNER 1122 Query: 1045 D-YESKLAQFTTKLENME---EEMQRVSKQLLDSKQHNEELQILVREQDDQIKELK-ETK 1099 D E K A+ ++ ++ EE + ++ ++K E + VRE+ Q+++ K + Sbjct: 1123 DEMEVKCARLEVDMKELQADLEEQKHMTTSNCEAKAALEAQLLAVREELSQLEQDKSRVE 1182 Query: 1100 LTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQE 1159 T E N E + TI +S + + ++ Q + Q+ QE Sbjct: 1183 ETLEKNRATLEER--TETISRLSREKELLSEKVQELATVLATVR-QTKSTIQQKLEEQQE 1239 Query: 1160 QSAKLNTELQECYTKIIQL-ETLN--TELTGHDVVNQ--------EQINQLKSKLEQLNT 1208 +S +L+ +L++ +K++ + E L TE ++ Q E++ +L + Sbjct: 1240 KSDELSCQLEDLNSKLLAVAEELGRVTEEKEAILIRQNAEKQELVEKVEELTESIAMAEE 1299 Query: 1209 ENDNLLSTVAELRSSISSAVDQRGF---EIAELWKQHLAQRE-ADFQKTEHELRV-QLSA 1263 + D L L++ + +G + +L KQ +RE A +K E+ + L Sbjct: 1300 DRDTLREEKCRLQAEVERIEHDKGSLDEQCGKLLKQLSKEREDAANEKARQEITIAALGE 1359 Query: 1264 FESKYEQLLDSVQSSTQEETNKIVTMEQV-TSLQNKLQDKEEHLRNLQEKYADVINQIEI 1322 ++ L ++ K+ +E+ T L+ L DK ++ K ++ I+ Sbjct: 1360 ERDALQEKLAAIDEERGALAGKVAELEETKTGLECALSDKGA----VESKVVELSKLIDE 1415 Query: 1323 LRSE---IEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKK 1379 LRSE +E E + ++RT +S K +Q Q + N NE N QL++ Sbjct: 1416 LRSEKMKLEGEWSSLSEELHSNNKTIEELKENVRTLEESKKNLQSQ-VSNGNETNKQLRQ 1474 Query: 1380 SSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQ 1439 + E + +L +L ++++ + + E T +Q E E + + Sbjct: 1475 EVQDLSKALQASKQEIEAMEVETKKLATELTQSEAKVEELSAEIKQTSSQL-QEVEAILK 1533 Query: 1440 QLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESV 1499 + + E+ +L ++R + + + + E+ +L + L +TES Sbjct: 1534 TKERESAVVSEKLVERTKDLELVRSQKEDVILQQSRNIESIQTEQQELAKRLQQVLTESS 1593 Query: 1500 SLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKI-QKHV 1558 + +V +L L + + + +E EI + + +T + S + Q + Sbjct: 1594 NREAEVKQLTGELNSRSLELKAKEQEVHAKEQEIRSATELLTASEAKAAELSLNVDQLNA 1653 Query: 1559 SFASDTKQGRDEQLDNTMNKELLDAVPRAELDLA 1592 + +S Q R Q D +EL A R DLA Sbjct: 1654 AKSSLEMQIRKLQDDFDHERELCQATERKAEDLA 1687 Score = 121 bits (292), Expect = 1e-25 Identities = 217/1113 (19%), Positives = 468/1113 (42%), Gaps = 83/1113 (7%) Query: 212 EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271 E+ K+++ M D + +L++ +E + S E ++ AR E+ ++ Sbjct: 1081 EEAAAGSEKLEQEIKQMNKAQSDLQAQLIEKLEQ--FKCVSNERDEMEVKCARLEVDMK- 1137 Query: 272 SKLAQELEQXXXXXXXXXXXXXXL------AKQSIEPSCEEKTEIEEKGSLEIANMTELT 325 +L +LE+ L ++ + ++K+ +EE A + E T Sbjct: 1138 -ELQADLEEQKHMTTSNCEAKAALEAQLLAVREELSQLEQDKSRVEETLEKNRATLEERT 1196 Query: 326 KKIELLEHLNCQIRQTNKELENKLATM----GTESKAVSSPSKKGSPLISRKSGRNTASK 381 + I L + + +EL LAT+ T + + +K L + N SK Sbjct: 1197 ETISRLSREKELLSEKVQELATVLATVRQTKSTIQQKLEEQQEKSDELSCQLEDLN--SK 1254 Query: 382 MKSPWSQLSSETLNQDT---DKKINKNEIA-KLEMVIQSLNKDLVDKEYVISEKDTXXXX 437 + + +L T ++ + K E+ K+E + +S+ D++ + EK Sbjct: 1255 LLAVAEELGRVTEEKEAILIRQNAEKQELVEKVEELTESIAMAEEDRDTLREEKCRLQAE 1314 Query: 438 XXXXXXGKDTLIAQL-QLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDV 496 K +L Q +L Q E + E IA + E+ + L +++ + Sbjct: 1315 VERIEHDKGSLDEQCGKLLKQLSKEREDAANEKARQEIT--IAALGEE-RDALQEKLAAI 1371 Query: 497 NVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNF-SKVSDSNK 555 + + K AE + T+ E ++K ++ K + ++ K ID S+ Sbjct: 1372 DEERGALAGKVAELEETKTGLECALSDKGAVESK------VVELSKLIDELRSEKMKLEG 1425 Query: 556 EIVRLTEELH-------HLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENL 608 E L+EELH L + V LEE K NLQ + +G + +++ ++ Sbjct: 1426 EWSSLSEELHSNNKTIEELKENVRTLEESKKNLQSQV---SNGNETNKQLRQEVQDLSKA 1482 Query: 609 AETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADIS-QLQSDQVCSEIKSVHLEEQ 667 + + I +E + L EL + K +E+ ++ S QLQ + + K Sbjct: 1483 LQASKQEIEAMEVETKKLATELTQSEAKVEELSAEIKQTSSQLQEVEAILKTKERESAVV 1542 Query: 668 IDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKM 727 + L K+L LV + Q I+ ++ +++++ +LQ + E+ + +++++ Sbjct: 1543 SEKLVERTKDLELVRSQKEDVILQQSRNIESIQTEQQELAKRLQQVLTESSNREAEVKQL 1602 Query: 728 SAEKIS---ELLAKIN--HEEQSKIQTQFGI----DAKIQERDLYIENIESELSKYKSRI 778 + E S EL AK H ++ +I++ + +AK E L ++ + + S + +I Sbjct: 1603 TGELNSRSLELKAKEQEVHAKEQEIRSATELLTASEAKAAELSLNVDQLNAAKSSLEMQI 1662 Query: 779 CRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVE 838 +L++ + + ERKA+ L + L E SE I+ + +++L + + Sbjct: 1663 RKLQDDFDHERELCQATERKAEDLAASLSEA----SESKIRLEHQLHQLEIERTNAESAN 1718 Query: 839 KQLLEIEHENKELQKKNQILLE----ENQNLQISLSDMQQHYNALVEKANRTDLAESEST 894 +QL++ + K K Q ++ E +L L +++ + L EK + +E Sbjct: 1719 QQLIQQLSDLKAQVAKQQTSIDAKDTEIHHLTEGLEKVKRIQSHLEEKVTDFESVVTEKD 1778 Query: 895 KYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNI 954 + +TQL L++ L+ I + + I + +++ + + + ++ +++ +NE Y Sbjct: 1779 EIETQLIRLQNELETIQDDKRR-IETELDAVKEEKADVDRRLIQQLQNYDTVNEAYRNER 1837 Query: 955 EYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKL 1014 E +L+A+ Q NLN ++E N L+ H + + E+ I E +K Sbjct: 1838 EANKELQAKQQ-------NLNKKLQEATAENALLVHTHESSKAQLAAK--EKRIAEQDKQ 1888 Query: 1015 NALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDS 1074 LK++ E + NQ++++ +M + + +S+L +L E+ + K + +S Sbjct: 1889 MEKLKREMENLFGKNQQMDSLASEFMHLKVE-KSELEAKKEELNEAIEQKEIEEKAMQES 1947 Query: 1075 KQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXX 1134 +H +E + V++Q+ T L ++ K E + ST E N++ Sbjct: 1948 MEHLKE-SLKVKQQELDSLHSDVTNLKESLHSLKIENSKLKSTHELQLTKMLNLELKNAE 2006 Query: 1135 XXXXXXXLKVQEEEEFIQERSVLQ-EQSAKLNTELQEC------YTKIIQLETLNTELTG 1187 K+++ EE + + + E ++K +T L++ K+ +LE L+ + Sbjct: 2007 QSK-----KIEKLEESLNKTEISHLEDNSKASTLLKQLEKYKGYMVKVQELEELHQKERE 2061 Query: 1188 HDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQRE 1247 + + I+ LK+KL + + + + RS++ + E + + + E Sbjct: 2062 LNKMLSGDIDVLKAKLSKHREKTEEKEQQWKQERSTLQQKITNEIKENEIKLRDYRIEYE 2121 Query: 1248 ADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQ 1280 + +K + ++ VQ + S + + + SS++ Sbjct: 2122 SKLEKMKEKMMVQSTIVSSTCDGAPEGIASSSE 2154 Score = 112 bits (270), Expect = 7e-23 Identities = 209/1102 (18%), Positives = 467/1102 (42%), Gaps = 85/1102 (7%) Query: 473 EDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSN 532 + + E A E+L+QE+ K + DL +L EQ +++E D +++ Sbjct: 1078 KQIEEAAAGSEKLEQEIKQMNKAQS--DLQAQLIEKLEQFKCVSNERDEMEVKCARLE-- 1133 Query: 533 HKLKLKQMQKTIDNFSKVSDSNKEI-VRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSG 591 + +K++Q ++ ++ SN E L +L + +++++LE++K ++ L + Sbjct: 1134 --VDMKELQADLEEQKHMTTSNCEAKAALEAQLLAVREELSQLEQDKSRVEETLEKNRAT 1191 Query: 592 RMIESDVYKKMIEMENLAETRLK----AISLLESQKFDLVQELHILQQKYDEVEDKLADI 647 ++ ++ + L +++ ++ + K + Q+L Q+K DE+ +L D+ Sbjct: 1192 LEERTETISRLSREKELLSEKVQELATVLATVRQTKSTIQQKLEEQQEKSDELSCQLEDL 1251 Query: 648 SQLQSDQVCSEIKSVHLEEQIDAL--SASKKELALVIENLKLDKEQLYGTIKDLENDKED 705 + + V E+ V E++ + +A K+EL +E L E + +D + +E+ Sbjct: 1252 NS-KLLAVAEELGRVTEEKEAILIRQNAEKQELVEKVEELT---ESIAMAEEDRDTLREE 1307 Query: 706 IMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIE 765 +LQ ++ L++ + + +L + K + + I A +ERD E Sbjct: 1308 KC-RLQAEVERIEHDKGSLDEQCGKLLKQLSKEREDAANEKARQEITIAALGEERDALQE 1366 Query: 766 N---IESELSKYKSRICRLEESIAVME---DRRYSLERKADQLGSYLQE----KQKAYSE 815 I+ E ++ LEE+ +E + ++E K +L + E K K E Sbjct: 1367 KLAAIDEERGALAGKVAELEETKTGLECALSDKGAVESKVVELSKLIDELRSEKMKLEGE 1426 Query: 816 YTIQEDELVNR---LAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDM 872 ++ +EL + + L ++ R +E+ ++ + + N+ L +E Q+L +L Sbjct: 1427 WSSLSEELHSNNKTIEELKENVRTLEESKKNLQSQVSNGNETNKQLRQEVQDLSKALQAS 1486 Query: 873 QQHYNAL-VE-KANRTDLAESEST---------KYQTQLRDLESNLKRITHEHQTLIVQK 921 +Q A+ VE K T+L +SE+ + +QL+++E+ LK T E ++ +V + Sbjct: 1487 KQEIEAMEVETKKLATELTQSEAKVEELSAEIKQTSSQLQEVEAILK--TKERESAVVSE 1544 Query: 922 K--KEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVE 979 K + +DLE+ + + + ++ + + + E +L+ L E N + Sbjct: 1545 KLVERTKDLELVRSQKEDVILQQSRNIESIQTEQQELAKRLQQVLTESSNREAEVKQLTG 1604 Query: 980 ELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSY 1039 ELN +LEL K + Q EQ I +L + K E+ ++N A+ S Sbjct: 1605 ELNSRSLEL------KAKEQEVHAKEQEIRSATELLTASEAKAAELSLNVDQLNAAKSSL 1658 Query: 1040 MSMVS------DYESKLAQFT-TKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQI 1092 + D+E +L Q T K E++ + S+ + + +L+I + Sbjct: 1659 EMQIRKLQDDFDHERELCQATERKAEDLAASLSEASESKIRLEHQLHQLEIERTNAESAN 1718 Query: 1093 KELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXL--KVQEEEEF 1150 ++L + + + K + ++I+ + +++ L KV + E Sbjct: 1719 QQLIQQLSDLKAQVAKQQ-----TSIDAKDTEIHHLTEGLEKVKRIQSHLEEKVTDFESV 1773 Query: 1151 IQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTEN 1210 + E+ ++ Q +L EL+ ++E TEL D V +E+ + + ++QL +N Sbjct: 1774 VTEKDEIETQLIRLQNELETIQDDKRRIE---TEL---DAVKEEKADVDRRLIQQL--QN 1825 Query: 1211 DNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQ 1270 + ++ + + + + + ++ A+ A T + QL+A E + + Sbjct: 1826 YDTVNEAYRNEREANKELQAKQQNLNKKLQEATAE-NALLVHTHESSKAQLAAKEKRIAE 1884 Query: 1271 LLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDE 1330 ++ +E N +Q+ SL ++ + L+ K ++ IE + EIE++ Sbjct: 1885 QDKQMEKLKREMENLFGKNQQMDSLASEFMHLKVEKSELEAKKEELNEAIE--QKEIEEK 1942 Query: 1331 KVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXX 1390 A +L + + ++E S+ ++ EN++LK + Sbjct: 1943 --AMQESMEHLKESLKVKQQELDSLHSDVTNLKE-SLHSLKIENSKLKSTHELQLTKMLN 1999 Query: 1391 XXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVR---QQLVEYEKR 1447 + + K+ +L L K + + + TL ++ ++++ Q+L E ++ Sbjct: 2000 LELKNAEQSKKIEKLEESLN-KTEISHLEDNSKASTLLKQLEKYKGYMVKVQELEELHQK 2058 Query: 1448 IEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITES-VSLNKQVA 1506 +L ++ +L+ K+ ++ E +++ + ER L +++ +I E+ + L Sbjct: 2059 ERELNKMLSGDIDVLKAKLSKHREKTEEKEQQWKQERSTLQQKITNEIKENEIKLRDYRI 2118 Query: 1507 ELNKALEEEVAKTNEMQTALEN 1528 E LE+ K T + + Sbjct: 2119 EYESKLEKMKEKMMVQSTIVSS 2140 Score = 103 bits (246), Expect = 5e-20 Identities = 175/947 (18%), Positives = 397/947 (41%), Gaps = 66/947 (6%) Query: 91 SESLANTLKQKEILMEKIKQYKEL--SKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLS 148 +E+++ ++KE+L EK+++ + + R + + ++ QL D+ S Sbjct: 1196 TETISRLSREKELLSEKVQELATVLATVRQTKSTIQQKLEEQQEKSDELSCQLEDLN--S 1253 Query: 149 NTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXX 208 + + V + K I+ + QE + + +++ E+ A Sbjct: 1254 KLLAVAEELGRVTEEKEAILIRQNAEKQELVEKVEELTESIAMA-EEDRDTLREEKCRLQ 1312 Query: 209 XXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEIS 268 E + + E + + E++ + +++ I++L E L+ I Sbjct: 1313 AEVERIEHDKGSLDEQCGKLLKQLSKEREDAANEKARQEITIAALGEERDALQEKLAAID 1372 Query: 269 LEHSKLA---QELEQXXXXXXXXXXXXXXLAKQSIEPS------CEEKTEIEEKGSLEIA 319 E LA ELE+ + + +E S EK ++E + S Sbjct: 1373 EERGALAGKVAELEETKTGLECALSDKGAVESKVVELSKLIDELRSEKMKLEGEWSSLSE 1432 Query: 320 NMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTA 379 + K IE L+ + ++ K L+++++ +K + + S + ++ + Sbjct: 1433 ELHSNNKTIEELKENVRTLEESKKNLQSQVSNGNETNKQLRQEVQDLSKAL--QASKQEI 1490 Query: 380 SKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKE---YVISEK--DTX 434 M+ +L++E + + EI + +Q + L KE V+SEK + Sbjct: 1491 EAMEVETKKLATELTQSEAKVEELSAEIKQTSSQLQEVEAILKTKERESAVVSEKLVERT 1550 Query: 435 XXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIH--VGTNTEDVNEIAKVQEQLKQELND- 491 +D ++ Q + E L TE N A+V +QL ELN Sbjct: 1551 KDLELVRSQKEDVILQQSRNIESIQTEQQELAKRLQQVLTESSNREAEV-KQLTGELNSR 1609 Query: 492 ----EIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNF 547 + K+ V ++++SA E +T + + N+ ++ + Q++K D+F Sbjct: 1610 SLELKAKEQEVHAKEQEIRSATELLTASEAKAAELSLNVDQLNAAKSSLEMQIRKLQDDF 1669 Query: 548 SKVSDSNKEIVRLTE-ELHHLSQKVAELEEEKGNL--QLHLVDYD--SGRMIESDVYKKM 602 D +E+ + TE + L+ ++E E K L QLH ++ + + + +++ Sbjct: 1670 ----DHERELCQATERKAEDLAASLSEASESKIRLEHQLHQLEIERTNAESANQQLIQQL 1725 Query: 603 IEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSV 662 +++ + +I +++ L + L +++ +E+K+ D + +++ E + + Sbjct: 1726 SDLKAQVAKQQTSIDAKDTEIHHLTEGLEKVKRIQSHLEEKVTDFESVVTEKDEIETQLI 1785 Query: 663 HLEEQIDALSASKKELALVIENLKLDKEQL-YGTIKDLENDKEDIMNKLQNYIQENMDLT 721 L+ +++ + K+ + ++ +K +K + I+ L+N + + +N + N +L Sbjct: 1786 RLQNELETIQDDKRRIETELDAVKEEKADVDRRLIQQLQN-YDTVNEAYRNEREANKELQ 1844 Query: 722 DK---LEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKY---K 775 K L K E +E ++ E SK Q + +I E+D +E ++ E+ Sbjct: 1845 AKQQNLNKKLQEATAENALLVHTHESSKAQLA-AKEKRIAEQDKQMEKLKREMENLFGKN 1903 Query: 776 SRICRLEESIAVMEDRRYSLERKADQLGSYLQEK---QKAYSEYT--IQEDELVNRLAVL 830 ++ L ++ + LE K ++L +++K +KA E ++E V + + Sbjct: 1904 QQMDSLASEFMHLKVEKSELEAKKEELNEAIEQKEIEEKAMQESMEHLKESLKVKQQELD 1963 Query: 831 MDHDRV--VEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDL 888 H V +++ L ++ EN +L+ +++ L + NL++ ++ + L E N+T++ Sbjct: 1964 SLHSDVTNLKESLHSLKIENSKLKSTHELQLTKMLNLELKNAEQSKKIEKLEESLNKTEI 2023 Query: 889 AESE-STKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLN 947 + E ++K T L+ LE ++ + VQ+ +E+ E E N + D VL Sbjct: 2024 SHLEDNSKASTLLKQLEK------YKGYMVKVQELEELHQKERELNKMLSG---DIDVLK 2074 Query: 948 EKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQ 994 K K+ E + E Q ++ ++ ++ N E+ + ++L D ++ Sbjct: 2075 AKLSKHREKTEEKEQQWKQERSTLQQKITN--EIKENEIKLRDYRIE 2119 Score = 79.0 bits (186), Expect = 1e-12 Identities = 181/993 (18%), Positives = 413/993 (41%), Gaps = 68/993 (6%) Query: 622 QKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALV 681 Q V++++I + Y+ + ++L + S ++ E KS LE+ + AL V Sbjct: 477 QDVGFVEKMNIFKSCYESLFEELGKFKE--SKEMLEE-KSDALEKDVRALKTELLARTEV 533 Query: 682 IENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQE-NMDLTDKLEKMS-AEKISELLAKI 739 +ENL+ + ++ ++ + K Q ++ N D L+ +S + +S+ + Sbjct: 534 LENLERHSADIERQLELVKQTANEYQRKNQALDEDVNRQKRDLLKLISEKDALSQQNLTL 593 Query: 740 NHEEQSKIQTQFGIDAKIQERDLYI-ENIE-SELSKYKSRICRLEESIAVM-EDRR---- 792 N E S + AKI L + E+ E S+ S + ++ L+E + + ED+ Sbjct: 594 NVEFNSLKGEHESLTAKIDYLMLSLNEDYEGSDFSSWFDKMDDLKERVRTLKEDKERLTG 653 Query: 793 YSLERKADQLG-----SYLQEKQKAYSEYTIQEDELVNRLA-VLMDHDRVVEKQ---LLE 843 +++ +++G S + + K E + ++ + RL+ L + ++ +E++ + Sbjct: 654 MNMKITMEKVGLEKHISVSEMRLKEMKELHAESEKKLRRLSEQLSESEKALEEKGNCVTS 713 Query: 844 IEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVE--KANRTDL--AESESTKYQTQ 899 +E +L++ Q L E Q L++M + + + E ++ R +L + E + + Sbjct: 714 LEKLKADLEENIQGLSAELLESQSKLNEMSEDFQSCEETLRSVRDELESRDQELSCAKNT 773 Query: 900 LRDLESNLKRITHEHQTLI-VQKKKEIEDLEIEFN-TQIESAIRDKKVLNEKYEKNIEYV 957 + +L++NL++ E Q+ + +Q++ E ++ N T ++ + ++ + ++ K +E V Sbjct: 774 IEELQTNLEKQQVELQSAMQLQQETASEKEQLAVNLTDVQQKLSEESEILQETIKKLEQV 833 Query: 958 TQLEAQLQEYKNNIENLNMNVEE-LNKMNLEL--IDKHVQKQQTQSPDYTEQYINEINKL 1014 +L E+++N++ + +EE L + EL K +Q + Q + + NE ++ Sbjct: 834 NLEWQKLTEHRDNLQQDKLILEEALAEQCNELGKNSKTIQNLELQLQNLQQLLANEADQS 893 Query: 1015 NALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEE-EMQRVSKQLLD 1073 + + +II +++ ++ + + S L + + E Q VSK Sbjct: 894 KETQQSLNAQIINQQHQLDASRKEQHILSAANRSLLTGLELVQGKITQLEGQYVSKIGTL 953 Query: 1074 SKQHNEELQILVREQDDQIKELKETKLTFEMNIPK--TEGMIISSTIEPMSDDANNVDXX 1131 + E +L + Q K L+ K E N+ K E I+ + + + + N + Sbjct: 954 EAKLGEFAALLTKLSAYQFK-LRLEKAQLEDNLGKMIREFEILQTENDKLLEVENALQQT 1012 Query: 1132 XXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLN-TELQECYTKIIQLETLNTELTG--- 1187 V+E ++E+ E LN ++E +LE T L G Sbjct: 1013 VQELRLEKTA--VEERSVGLEEQLAEMEVRVDLNGNRIKELEGSCAELEAERTRLLGDGS 1070 Query: 1188 -HDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQR 1246 + Q+QI + + E+L E + ++L++ + ++Q F+ + + + Sbjct: 1071 QREKELQKQIEEAAAGSEKLEQEIKQMNKAQSDLQAQLIEKLEQ--FKCVSNERDEMEVK 1128 Query: 1247 EADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHL 1306 A + EL+ L E + + ++ E + E+++ L+ QDK Sbjct: 1129 CARLEVDMKELQADL---EEQKHMTTSNCEAKAALEAQLLAVREELSQLE---QDKSRVE 1182 Query: 1307 RNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQS 1366 L++ A + + E + S + EK T Q ++ QE+S Sbjct: 1183 ETLEKNRATLEERTETI-SRLSREKELLSEKVQELATVLATVRQTKSTIQQKLEEQQEKS 1241 Query: 1367 ILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTIT 1426 +E + QL+ + + EA ++ + + E+ +K E T + Sbjct: 1242 ----DELSCQLEDLNSKLLAVAEELGRVTEEKEAILI----RQNAEKQELVEKVEELTES 1293 Query: 1427 LTQRNDEFENVRQQLVEYEKRIEDLTYEK---ESELAILRLKMHENANHYETMQKESEIE 1483 + ++ + +R++ + +E + ++K + + L ++ + + EI Sbjct: 1294 IAMAEEDRDTLREEKCRLQAEVERIEHDKGSLDEQCGKLLKQLSKEREDAANEKARQEIT 1353 Query: 1484 RVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNL 1543 L EE + + E ++ + E AL +VA+ E +T LE + + ++ L Sbjct: 1354 IAALGEERDA-LQEKLA---AIDEERGALAGKVAELEETKTGLECALSDKGAVESKVVEL 1409 Query: 1544 QNMV---RASSSKIQKHVSFASDTKQGRDEQLD 1573 ++ R+ K++ S S+ ++ ++ Sbjct: 1410 SKLIDELRSEKMKLEGEWSSLSEELHSNNKTIE 1442 Score = 65.3 bits (152), Expect = 1e-08 Identities = 138/741 (18%), Positives = 283/741 (38%), Gaps = 36/741 (4%) Query: 863 QNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKK 922 + + I S + + L + ++ E +S + +R L++ L T + L Sbjct: 483 EKMNIFKSCYESLFEELGKFKESKEMLEEKSDALEKDVRALKTELLARTEVLENLERHSA 542 Query: 923 KEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELN 982 LE+ T E R + L+E + + +L ++ LN+ L Sbjct: 543 DIERQLELVKQTANEYQ-RKNQALDEDVNRQKRDLLKLISEKDALSQQNLTLNVEFNSLK 601 Query: 983 KMNLELIDKHVQKQQTQSPDYT-EQYINEINKLNAL------LKQKDEEIIALNQKINNA 1035 + L K + + DY + + +K++ L LK+ E + +N KI Sbjct: 602 GEHESLTAKIDYLMLSLNEDYEGSDFSSWFDKMDDLKERVRTLKEDKERLTGMNMKITME 661 Query: 1036 QVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEE-------LQILVREQ 1088 +V +S E +L + E++++R+S+QL +S++ EE L+ L + Sbjct: 662 KVGLEKHISVSEMRLKEMKELHAESEKKLRRLSEQLSESEKALEEKGNCVTSLEKLKADL 721 Query: 1089 DDQIKELKETKLTFE--MNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQE 1146 ++ I+ L L + +N + T+ + D+ + D L+ Sbjct: 722 EENIQGLSAELLESQSKLNEMSEDFQSCEETLRSVRDELESRDQELSCAKNTIEELQTNL 781 Query: 1147 EEEFIQERSV--LQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLE 1204 E++ ++ +S LQ+++A +L T + Q + +E+ + EQ+N KL Sbjct: 782 EKQQVELQSAMQLQQETASEKEQLAVNLTDVQQKLSEESEILQETIKKLEQVNLEWQKLT 841 Query: 1205 QL--NTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLS 1262 + N + D L+ A + + + EL Q+L Q A+ E + L+ Sbjct: 842 EHRDNLQQDKLILEEALAEQCNELGKNSKTIQNLELQLQNLQQLLANEADQSKETQQSLN 901 Query: 1263 AFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEI 1322 A + LD+ S ++ +T L+ +Q K + L+ +Y I +E Sbjct: 902 AQIINQQHQLDA--SRKEQHILSAANRSLLTGLE-LVQGK---ITQLEGQYVSKIGTLEA 955 Query: 1323 LRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSX 1382 E +L + ++ +Q ++ + ENA L+++ Sbjct: 956 KLGEFAALLTKLSAYQFKLRLEKAQLEDNLGKMIREFEILQTENDKLLEVENA-LQQTVQ 1014 Query: 1383 XXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLV 1442 R E ++ E+ +++L + I + +R + Q+ Sbjct: 1015 ELRLEKTAVEERSVGLEEQLAEMEVRVDLNGNRIKELEGSCAELEAERTRLLGDGSQREK 1074 Query: 1443 EYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLI-EELNVKITESVSL 1501 E +K+IE+ SE +K A Q ++E+ K + E + + L Sbjct: 1075 ELQKQIEEAA--AGSEKLEQEIKQMNKAQSDLQAQLIEKLEQFKCVSNERDEMEVKCARL 1132 Query: 1502 NKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFA 1561 + EL LEE+ T A E +++ + +E++ L+ S++++ + Sbjct: 1133 EVDMKELQADLEEQKHMTTSNCEAKAALEAQLLAVREELSQLEQ----DKSRVEETLEKN 1188 Query: 1562 SDTKQGRDEQLDN-TMNKELL 1581 T + R E + + KELL Sbjct: 1189 RATLEERTETISRLSREKELL 1209 Score = 54.4 bits (125), Expect = 2e-05 Identities = 140/737 (18%), Positives = 300/737 (40%), Gaps = 59/737 (8%) Query: 838 EKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQ 897 EK LE++ K+LQ KN+ LE+ + + +++ A NR E+ES Q Sbjct: 231 EKGYLEVQL--KQLQDKNEKFLEDKRKYVKEIRELRTELQA----CNR----ENESPNKQ 280 Query: 898 TQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYV 957 R + + RI + L+ +K++ ++ L IE T E+ +++N +N++ + Sbjct: 281 ---RGADHKVARI----ERLLAEKEEALDRLRIELETVAENNRNSTEMIN---YRNVQ-I 329 Query: 958 TQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNAL 1017 +L+ Q+QE +N++ +L+ + E +++ L + + + Q+ +Q I LN Sbjct: 330 VKLKDQIQELENSLGSLSECIAEKDEVIKCLRENNEELQRFIEESRFKQNIPLPENLNTS 389 Query: 1018 LKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQH 1077 E + N SY + + K + E + + S ++++ ++ Sbjct: 390 FDGMMELSSGGSSNGNGTGRSYNITPENMAHAVVDVQLKEKEAENCLLKRSLEIIEQEKV 449 Query: 1078 NEE--LQILVREQDDQIKELKETKLTFEMNIPKTEGM-IISSTIEPMSDDANNVDXXXXX 1134 + R D + + ++ E M I S E + ++ Sbjct: 450 RVSGLVGSFFRLYGDLVGAMPYGSAN-PQDVGFVEKMNIFKSCYESLFEELGKFKESKEM 508 Query: 1135 XXXXXXXLK--VQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVN 1192 L+ V+ + + R+ + E + + +++ QLE + + N Sbjct: 509 LEEKSDALEKDVRALKTELLARTEVLENLERHSADIER------QLELVKQTANEYQRKN 562 Query: 1193 Q---EQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREAD 1249 Q E +N+ K L +L +E D L L +S + A++ L+ E D Sbjct: 563 QALDEDVNRQKRDLLKLISEKDALSQQNLTLNVEFNSLKGEHESLTAKIDYLMLSLNE-D 621 Query: 1250 FQKTEHELRVQLSAFESKYEQLLDSVQSSTQEE-----TNKIVTMEQVTSLQNKLQDKEE 1304 ++ ++ S++ K + L + V++ +++ N +TME+V L+ + E Sbjct: 622 YEGSD------FSSWFDKMDDLKERVRTLKEDKERLTGMNMKITMEKV-GLEKHISVSEM 674 Query: 1305 HLRNLQEKYADVINQIEILRSEI-EDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQ 1363 L+ ++E +A+ ++ L ++ E EK + + S + ++ Sbjct: 675 RLKEMKELHAESEKKLRRLSEQLSESEKALEEKGNCVTSLEKLKADLEENIQGLSAELLE 734 Query: 1364 EQSILN-INEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHE 1422 QS LN ++E+ +++ ++ A+ + EL LE + E+ Sbjct: 735 SQSKLNEMSEDFQSCEETLRSVRDELESRDQELSCAKNTIEELQTNLEKQQVELQSAMQL 794 Query: 1423 YTITLTQRNDEFENVR--QQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKES 1480 T +++ N+ QQ + E I T +K L + L+ + H + +Q++ Sbjct: 795 QQETASEKEQLAVNLTDVQQKLSEESEILQETIKK---LEQVNLEWQKLTEHRDNLQQDK 851 Query: 1481 EIERVKLIEELNV--KITESV-SLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLN 1537 I L E+ N K ++++ +L Q+ L + L E ++ E Q +L Q I Sbjct: 852 LILEEALAEQCNELGKNSKTIQNLELQLQNLQQLLANEADQSKETQQSLNAQIINQQHQL 911 Query: 1538 DEITNLQNMVRASSSKI 1554 D Q+++ A++ + Sbjct: 912 DASRKEQHILSAANRSL 928 >UniRef50_A0BIX7 Cluster: Chromosome undetermined scaffold_11, whole genome shotgun sequence; n=2; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_11, whole genome shotgun sequence - Paramecium tetraurelia Length = 1014 Score = 128 bits (308), Expect = 2e-27 Identities = 198/976 (20%), Positives = 437/976 (44%), Gaps = 80/976 (8%) Query: 395 NQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQL 454 NQ + + +EI++L++ + + ++ + ++ D K+T +++ L Sbjct: 3 NQSPEPEKQSDEISRLKLSLMMKDNEIRALKLKVNPSDEIERLQQEAEKMKETYESEINL 62 Query: 455 EHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQ 514 +++ E L+ T+D E K K + E+K N D I K +S ++ Q Sbjct: 63 LKEENYEYSELLK---ETQDQAEFLKSVVIGKDKEIAELKSQNANDEIVKSRSRNGEL-Q 118 Query: 515 LNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAEL 574 L +A KN +++ KL + K + + S V L+ +Q ++ L Sbjct: 119 LALAENANLKNELQILQT-KLDDAYLSKQVMDEQLQSLGQMLEVEQRNTLNQANQ-ISTL 176 Query: 575 EEEKGNLQLHLVDYDSGRMIESDVYK-KMIEMENLAETRLKAISLLESQKFDLVQELHIL 633 ++E L+ + D + + + + K K E+ E ++ L + D + Sbjct: 177 QKEAQYLRNSVNDRERFIVGKEKIIKLKDGEINRQQEIINDTLAKLAEMQHDNQVIVTQN 236 Query: 634 QQKYDEVEDKLADISQLQSDQV---CSEIKSV-HLEEQIDALSASKKELALVIENLKLDK 689 Q Y +++K A+I L+ DQ+ +++ V + E Q + A K+LA I+ L+ Sbjct: 237 DQYYKLLQEKQAEIDSLK-DQLQFFAEDLQRVQNYEGQYNDAQAKIKQLAQYIQELE--- 292 Query: 690 EQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQT 749 +QL + E ++++N + E D+LEK ++ K ++L A+ +++ S++Q Sbjct: 293 KQLQDQMNQYEKQIKELLNNAKATEDEKDHNIDQLEKDNSNKANQLEAQ--NKQISQLQK 350 Query: 750 QFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEK 809 + DA +RD +++++ +L + L+++ ++D+ + +A Q+ + +E Sbjct: 351 ELK-DAD-NKRDREVKDVQRKLDAELKKTATLDKNNKTLKDKN---DEQAKQINAANEEL 405 Query: 810 QKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISL 869 D+L ++A L + + Q+ ++E E K+L K+ Q L+++N NL Sbjct: 406 -----------DQLDQKIADLEQKVKDQQNQIKDLEKEIKDLNKEKQNLIQDNNNLH--- 451 Query: 870 SDMQQHYNALVEKA--NRTDL--AESESTKYQTQLRDLESNLKRITHEHQTL---IVQKK 922 Q +N EKA + DL A+ E L +L E++ L I Sbjct: 452 ----QKFNQAEEKALQQQKDLVKAQKELNDKHNNAEQLNKDLDEYEQENKELQKEINSLN 507 Query: 923 KEIEDLEIEFN---TQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVE 979 +I L E N QI+ +D + L E EK + + + ++ + N +LN + Sbjct: 508 DQINQLNKEINQKQKQIDQQAKDIQKLQENLEKQKQDNQSKQQENKQLQQNNNDLNKQLN 567 Query: 980 ELNKMNLELIDK--HVQKQQTQSPDYTEQYI----NEINKLNALLKQKDEEIIALNQKIN 1033 E K N +L D+ + +++Q ++ D + + NEI +L +K++++E L ++N Sbjct: 568 ESKKQNQKLQDQINNTEQKQNKTQDQLKNQLQDAQNEIKQLKDQIKEQEKEKKNLQNEVN 627 Query: 1034 NAQVSYMSMVSDYESKL--AQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQ 1091 N + + + K+ Q +++ + +E+ + +QL KQ ++L V+ + ++ Sbjct: 628 NLNKECDDLDAKLQQKIKEQQENSEINRLNDELNKAQQQL---KQKEDQL-TKVQNELNK 683 Query: 1092 IKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLK--VQEEEE 1149 +KE K+ K E + + ++ + + +++D LK +Q + Sbjct: 684 LKEQKQ-KEQKEQKDKDQQRKDLEKQVKDLDAECDHLDQQRQAAINEAEKLKQELQNLND 742 Query: 1150 FIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVV---NQ--EQINQLKSKLE 1204 ++ Q + A+ ++ + + ++ + E + + NQ + +++ S+L+ Sbjct: 743 LKKQLKDTQNKLAQAEKQIAQLDPEAVKNKLQKAEQDAKNAIQAQNQAKKDLDKANSQLK 802 Query: 1205 QLNTENDNLLSTVAELRSSISSAVD---QRGFEIAELWKQ--HLAQREADFQKTEHELRV 1259 Q EN +L L + + + + Q+ EI E KQ L + +K + + + Sbjct: 803 QKEKENKDLDDECNALDTQVQNLKEQAKQQEDEIKEKQKQIDQLQKENQQLKKDDIKGEI 862 Query: 1260 -QLSAFESKYEQLLDSVQ-SSTQEETNKIVTMEQVTSLQ---NKLQDKEEHLRNLQEKYA 1314 +L F + + +LD+++ STQ + + +Q+ Q NKL+ K+ + ++ Sbjct: 863 DKLRKFIQEQKPILDNLEKESTQSDKRRSDLEKQIAKSQDDLNKLKKKKGGNGDDDQQIQ 922 Query: 1315 DVINQIEILRSEIEDE 1330 ++ +++ L ++++ E Sbjct: 923 GLVQKLDELDNKLQQE 938 Score = 126 bits (304), Expect = 5e-27 Identities = 184/853 (21%), Positives = 388/853 (45%), Gaps = 78/853 (9%) Query: 527 IKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLV 586 +K+K N +++++Q+ + + +S EI L EE + S+ + E +++ L+ ++ Sbjct: 32 LKLKVNPSDEIERLQQEAEKMKETYES--EINLLKEENYEYSELLKETQDQAEFLKSVVI 89 Query: 587 DYDSGRMIESDVYKKMIEMENLAETRLK--AISLLESQKFDLVQELHILQQKYDEVE-DK 643 D E K + + ++R + + L ++ +L EL ILQ K D+ K Sbjct: 90 GKDK----EIAELKSQNANDEIVKSRSRNGELQLALAENANLKNELQILQTKLDDAYLSK 145 Query: 644 LADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQ-LYGT-----IK 697 QLQS E++ + Q + +S +KE A + N D+E+ + G +K Sbjct: 146 QVMDEQLQSLGQMLEVEQRNTLNQANQISTLQKE-AQYLRNSVNDRERFIVGKEKIIKLK 204 Query: 698 DLE-NDKEDIMN----KLQNYIQENMDLT---DKLEKMSAEKISELLAKINH-----EEQ 744 D E N +++I+N KL +N + D+ K+ EK +E+ + + E+ Sbjct: 205 DGEINRQQEIINDTLAKLAEMQHDNQVIVTQNDQYYKLLQEKQAEIDSLKDQLQFFAEDL 264 Query: 745 SKIQTQFG----IDAKIQERDLYIENIESEL----SKYKSRICRLEESIAVMEDRRYSLE 796 ++Q G AKI++ YI+ +E +L ++Y+ +I L + ED + + Sbjct: 265 QRVQNYEGQYNDAQAKIKQLAQYIQELEKQLQDQMNQYEKQIKELLNNAKATEDEK---D 321 Query: 797 RKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQ 856 DQL KA ++ Q ++ L D D ++++ +++ + KK Sbjct: 322 HNIDQLEK--DNSNKA-NQLEAQNKQISQLQKELKDADNKRDREVKDVQRKLDAELKKTA 378 Query: 857 ILLEENQNLQISLSDMQQHYNALVEKANRTD--LAESEST--KYQTQLRDLESNLKRITH 912 L + N+ L+ + + NA E+ ++ D +A+ E Q Q++DLE +K + Sbjct: 379 TLDKNNKTLKDKNDEQAKQINAANEELDQLDQKIADLEQKVKDQQNQIKDLEKEIKDLNK 438 Query: 913 EHQTLIVQKK---KEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKN 969 E Q LI ++ E + Q + ++ +K LN+K+ + L+ QE K Sbjct: 439 EKQNLIQDNNNLHQKFNQAEEKALQQQKDLVKAQKELNDKHNNAEQLNKDLDEYEQENKE 498 Query: 970 NIENLNMNVEELNKMNLELIDKHVQ-KQQTQSPDYTEQYINEINKLNALLKQKDEEIIA- 1027 + +N +++N++N E+ K Q QQ + ++ + + + N +Q+++++ Sbjct: 499 LQKEINSLNDQINQLNKEINQKQKQIDQQAKDIQKLQENLEKQKQDNQSKQQENKQLQQN 558 Query: 1028 ---LNQKINNAQVSYMSM---VSDYESKLAQFTTKLENMEEEMQRVSKQLLDS-KQHNEE 1080 LN+++N ++ + +++ E K + +L+N ++ Q KQL D K+ +E Sbjct: 559 NNDLNKQLNESKKQNQKLQDQINNTEQKQNKTQDQLKNQLQDAQNEIKQLKDQIKEQEKE 618 Query: 1081 LQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXX 1140 + L E ++ KE + + I + + +S I ++D+ N Sbjct: 619 KKNLQNEVNNLNKECDDLDAKLQQKIKEQQE---NSEINRLNDELNKAQQQLKQKEDQLT 675 Query: 1141 XLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLK 1200 KVQ E ++E+ +++ K + ++ K Q++ L+ E D Q IN+ + Sbjct: 676 --KVQNELNKLKEQKQKEQKEQKDKDQQRKDLEK--QVKDLDAECDHLDQQRQAAINEAE 731 Query: 1201 SKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQ 1260 ++L ND L + + ++ ++ A Q IA+L + + + QK E + + Sbjct: 732 KLKQELQNLND-LKKQLKDTQNKLAQAEKQ----IAQLDPEAVKNK---LQKAEQDAKNA 783 Query: 1261 LSAFESKYEQLLDSVQSSTQ--EETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVIN 1318 + A +++ ++ LD S + E+ NK + ++ +L ++Q+ +E + +++ + Sbjct: 784 IQA-QNQAKKDLDKANSQLKQKEKENKDLD-DECNALDTQVQNLKEQAKQQEDEIKEKQK 841 Query: 1319 QIEILRSEIEDEK 1331 QI+ L+ E + K Sbjct: 842 QIDQLQKENQQLK 854 Score = 115 bits (277), Expect = 9e-24 Identities = 179/955 (18%), Positives = 408/955 (42%), Gaps = 57/955 (5%) Query: 101 KEILMEKIKQYKEL-SKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNALS 159 K +++ K K+ EL S+ ++ IV+ L + +L N ++ L Sbjct: 85 KSVVIGKDKEIAELKSQNANDEIVKSRSRNGELQLA-----LAENANLKNELQILQTKLD 139 Query: 160 VLQVKMKIMETTILDLQE--KINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQ 217 + ++M+ + L + ++ +++ + +A +T K++ Sbjct: 140 DAYLSKQVMDEQLQSLGQMLEVEQRNTLNQANQISTLQKEAQYLRNSVNDRERFIVGKEK 199 Query: 218 MTKMQENFIAMEAEWKDEKQRLLKDIE-SKDVRISSLEEANKLLEAARFEISLEHSKL-- 274 + K+++ I + E ++ L +++ V ++ ++ KLL+ + EI +L Sbjct: 200 IIKLKDGEINRQQEIINDTLAKLAEMQHDNQVIVTQNDQYYKLLQEKQAEIDSLKDQLQF 259 Query: 275 -AQELEQXXXXXXXXXXXXXXLAK-----QSIEPSCEEKTEIEEKGSLEIANMTELTKKI 328 A++L++ + + Q +E +++ EK E+ N + T+ Sbjct: 260 FAEDLQRVQNYEGQYNDAQAKIKQLAQYIQELEKQLQDQMNQYEKQIKELLNNAKATEDE 319 Query: 329 ELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQ 388 + +H I Q K+ NK + ++K +S K+ K R + ++ Sbjct: 320 K--DH---NIDQLEKDNSNKANQLEAQNKQISQLQKELKDA-DNKRDREVKDVQRKLDAE 373 Query: 389 LSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTL 448 L +T D + K K++ + I + N++L + I++ + + Sbjct: 374 LK-KTATLDKNNKTLKDKNDEQAKQINAANEELDQLDQKIADLEQKVKDQQNQIKDLEKE 432 Query: 449 IAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLK--QELNDEIKDVNV--KDLIE- 503 I L E Q ++ + +H N + + + ++ +K +ELND+ + KDL E Sbjct: 433 IKDLNKEKQNLIQDNNNLHQKFNQAEEKALQQQKDLVKAQKELNDKHNNAEQLNKDLDEY 492 Query: 504 --KLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNK----EI 557 + K +++I LND+I+ NK + + + + K +QK +N K N+ E Sbjct: 493 EQENKELQKEINSLNDQINQLNKEINQKQKQIDQQAKDIQKLQENLEKQKQDNQSKQQEN 552 Query: 558 VRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLK-AI 616 +L + + L++++ E +++ LQ + + + + D K ++ +LK I Sbjct: 553 KQLQQNNNDLNKQLNESKKQNQKLQDQINNTEQKQNKTQDQLKNQLQDAQNEIKQLKDQI 612 Query: 617 SLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVH--LEEQIDALSAS 674 E +K +L E++ L ++ D+++ KL +++ Q SEI ++ L + L Sbjct: 613 KEQEKEKKNLQNEVNNLNKECDDLDAKLQQ--KIKEQQENSEINRLNDELNKAQQQLKQK 670 Query: 675 KKELALV---IENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQE--NMDLTDKLEKMSA 729 + +L V + LK K++ KD + ++D+ ++++ E ++D + A Sbjct: 671 EDQLTKVQNELNKLKEQKQKEQKEQKDKDQQRKDLEKQVKDLDAECDHLDQQRQAAINEA 730 Query: 730 EKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVME 789 EK+ + L +N ++ TQ K+ + + I ++ E K K + + A+ Sbjct: 731 EKLKQELQNLNDLKKQLKDTQ----NKLAQAEKQIAQLDPEAVKNKLQKAEQDAKNAIQA 786 Query: 790 DRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENK 849 + ++ D+ S L++K+K + + + L ++ L + + E ++ E + + Sbjct: 787 QNQ--AKKDLDKANSQLKQKEKENKDLDDECNALDTQVQNLKEQAKQQEDEIKEKQKQID 844 Query: 850 ELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKR 909 +LQK+NQ L +++ +I D + + + E+ D E EST+ + DLE + + Sbjct: 845 QLQKENQQLKKDDIKGEI---DKLRKF--IQEQKPILDNLEKESTQSDKRRSDLEKQIAK 899 Query: 910 ITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKN 969 + + + +KK D + + ++ L ++ +K IE V+ +E L + Sbjct: 900 -SQDDLNKLKKKKGGNGDDDQQIQGLVQKLDELDNKLQQEVDKYIESVSNIEKLLTDITE 958 Query: 970 NIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEE 1024 + L + + E+ + + + + Q + DY + + LLKQ +++ Sbjct: 959 KLLKLKLQINEVQEEDGQQFNDVFQLVKNLCNDYKQGLATHNQAMEDLLKQINKQ 1013 Score = 102 bits (245), Expect = 7e-20 Identities = 141/645 (21%), Positives = 295/645 (45%), Gaps = 75/645 (11%) Query: 480 KVQEQLKQ--ELNDEIK--DVNVKDLIEKLKSAEEQITQLNDEIDAANK---NMIKVKSN 532 K EQ KQ N+E+ D + DL +K+K + QI L EI NK N+I+ +N Sbjct: 390 KNDEQAKQINAANEELDQLDQKIADLEQKVKDQQNQIKDLEKEIKDLNKEKQNLIQDNNN 449 Query: 533 HKLKLKQMQ-KTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDY-DS 590 K Q + K + + + KE+ L++ + E E+E LQ + D Sbjct: 450 LHQKFNQAEEKALQQQKDLVKAQKELNDKHNNAEQLNKDLDEYEQENKELQKEINSLNDQ 509 Query: 591 GRMIESDVYKKMIEMENLAETRLKAISLLESQKFD---LVQELHILQQKYDEVEDKLADI 647 + ++ +K +++ A+ K LE QK D QE LQQ +++ +L + Sbjct: 510 INQLNKEINQKQKQIDQQAKDIQKLQENLEKQKQDNQSKQQENKQLQQNNNDLNKQLNE- 568 Query: 648 SQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIM 707 S+ Q+ ++ +I + ++ + ++ +L +++ + + +QL IK+ E +K+++ Sbjct: 569 SKKQNQKLQDQINNTEQKQ-----NKTQDQLKNQLQDAQNEIKQLKDQIKEQEKEKKNLQ 623 Query: 708 NKLQNYIQENMDLTDKLE-KMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIEN 766 N++ N +E DL KL+ K+ ++ + + ++N +E +K Q Q +++++ + Sbjct: 624 NEVNNLNKECDDLDAKLQQKIKEQQENSEINRLN-DELNKAQQQ------LKQKEDQLTK 676 Query: 767 IESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYL----QEKQKAYSEYTIQEDE 822 +++EL+K K + + ++ + +R LE++ L + Q++Q A +E + E Sbjct: 677 VQNELNKLKEQKQKEQKEQKDKDQQRKDLEKQVKDLDAECDHLDQQRQAAINEAEKLKQE 736 Query: 823 LVN------RLAVLMDHDRVVEKQLLEIEHE--NKELQKKNQILLEENQNLQISLSDMQQ 874 L N +L + EKQ+ +++ E +LQK Q Q + D+ + Sbjct: 737 LQNLNDLKKQLKDTQNKLAQAEKQIAQLDPEAVKNKLQKAEQDAKNAIQAQNQAKKDLDK 796 Query: 875 HYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNT 934 + L +K + E TQ+++L+ K+ E I +K+K+I+ L+ E N Sbjct: 797 ANSQLKQKEKENKDLDDECNALDTQVQNLKEQAKQQEDE----IKEKQKQIDQLQKE-NQ 851 Query: 935 Q-----IESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIEN-LNMNVEELNKMNLEL 988 Q I+ I + ++ + ++ + + Q + ++++E + + ++LNK+ + Sbjct: 852 QLKKDDIKGEIDKLRKFIQEQKPILDNLEKESTQSDKRRSDLEKQIAKSQDDLNKLKKKK 911 Query: 989 IDKHVQKQQTQS------------PDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQ 1036 QQ Q ++YI ++ + LL E+++ L +IN Q Sbjct: 912 GGNGDDDQQIQGLVQKLDELDNKLQQEVDKYIESVSNIEKLLTDITEKLLKLKLQINEVQ 971 Query: 1037 VS-----------YMSMVSDYESKLAQFTTKLENMEEEMQRVSKQ 1070 ++ +DY+ LA T + ME+ +++++KQ Sbjct: 972 EEDGQQFNDVFQLVKNLCNDYKQGLA---THNQAMEDLLKQINKQ 1013 Score = 89.8 bits (213), Expect = 5e-16 Identities = 195/959 (20%), Positives = 405/959 (42%), Gaps = 114/959 (11%) Query: 665 EEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKL 724 E+Q D +S K L + ++ K +K +D+ + + + ++E + L Sbjct: 9 EKQSDEISRLKLSLMMKDNEIRALK------LKVNPSDEIERLQQEAEKMKETYESEINL 62 Query: 725 EKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEES 784 K + SELL + + + G D +I E L +N E+ K +SR L+ + Sbjct: 63 LKEENYEYSELLKETQDQAEFLKSVVIGKDKEIAE--LKSQNANDEIVKSRSRNGELQLA 120 Query: 785 IAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEI 844 +A +L+ + L + L + AY + +++L + Q+LE+ Sbjct: 121 LA----ENANLKNELQILQTKLDD---AYLSKQVMDEQLQSL------------GQMLEV 161 Query: 845 EHENKELQKKNQI--LLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRD 902 E N L + NQI L +E Q L+ S++D ++ +V K L + E + Q + D Sbjct: 162 EQRNT-LNQANQISTLQKEAQYLRNSVNDRERF---IVGKEKIIKLKDGEINRQQEIIND 217 Query: 903 LESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEA 962 + L + H++Q ++ Q + + L+ E +I+S ++D+ + + ++++ V E Sbjct: 218 TLAKLAEMQHDNQVIVTQNDQYYKLLQ-EKQAEIDS-LKDQL---QFFAEDLQRVQNYEG 272 Query: 963 QLQEYKNNIENLNMNVEELNKM---NLELIDKHVQKQQTQSPDYTEQYINEINKLNALLK 1019 Q + + I+ L ++EL K + +K +++ + ++ + I++L Sbjct: 273 QYNDAQAKIKQLAQYIQELEKQLQDQMNQYEKQIKELLNNAKATEDEKDHNIDQLEKDNS 332 Query: 1020 QKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNE 1079 K ++ A N++I+ Q + + ++ KL+ ++ + K K N+ Sbjct: 333 NKANQLEAQNKQISQLQKELKDADNKRDREVKDVQRKLDAELKKTATLDKNNKTLKDKND 392 Query: 1080 ELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXX 1139 E + ++++ +L + E + + I +E D N Sbjct: 393 EQAKQINAANEELDQLDQKIADLEQKVKDQQNQI--KDLEKEIKDLNKEKQNLIQDNNNL 450 Query: 1140 XXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQL 1199 Q EE+ +Q++ L + +LN + E LN +L ++ N+E ++ Sbjct: 451 HQKFNQAEEKALQQQKDLVKAQKELNDKHNNA-------EQLNKDLDEYEQENKELQKEI 503 Query: 1200 KSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRV 1259 S +Q+N N + + +DQ+ +I +L +++L +++ D Q + E + Sbjct: 504 NSLNDQINQLNKEI--------NQKQKQIDQQAKDIQKL-QENLEKQKQDNQSKQQENK- 553 Query: 1260 QLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQ 1319 QL + + L+ + Q+ ++I EQ QNK QD+ L+ + D N+ Sbjct: 554 QLQQNNNDLNKQLNESKKQNQKLQDQINNTEQK---QNKTQDQ------LKNQLQDAQNE 604 Query: 1320 IEILRSEI-EDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLK 1378 I+ L+ +I E EK D + + Q K+ QE S IN N +L Sbjct: 605 IKQLKDQIKEQEKEKKNLQNEVNNLNKECDDLDAKLQ-QKIKEQQENS--EINRLNDELN 661 Query: 1379 KSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVR 1438 K+ ++ E ++ ++ ++L K E QK + E ++ Sbjct: 662 KAQQ-----------QLKQKEDQLTKVQNELN-KLKEQKQKEQK----------EQKDKD 699 Query: 1439 QQLVEYEKRIEDLTYE-----KESELAI---LRLKMH-ENANHYETMQKESE---IERVK 1486 QQ + EK+++DL E ++ + AI +LK +N N + K+++ + K Sbjct: 700 QQRKDLEKQVKDLDAECDHLDQQRQAAINEAEKLKQELQNLNDLKKQLKDTQNKLAQAEK 759 Query: 1487 LIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTA---LENQEIEIVTLNDEITNL 1543 I +L+ + ++ L K + A++ + ++ A L+ +E E L+DE L Sbjct: 760 QIAQLDPEAVKN-KLQKAEQDAKNAIQAQNQAKKDLDKANSQLKQKEKENKDLDDECNAL 818 Query: 1544 QNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELD-LAMYMLHQRDV 1601 V+ + ++ + KQ + +QL N++L + E+D L ++ Q+ + Sbjct: 819 DTQVQNLKEQAKQQEDEIKE-KQKQIDQLQKE-NQQLKKDDIKGEIDKLRKFIQEQKPI 875 Score = 89.4 bits (212), Expect = 7e-16 Identities = 128/620 (20%), Positives = 267/620 (43%), Gaps = 75/620 (12%) Query: 999 QSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLE 1058 QSP+ E+ +EI++L L KD EI AL K+N + + + E + +++ Sbjct: 4 QSPE-PEKQSDEISRLKLSLMMKDNEIRALKLKVNPSD-EIERLQQEAEKMKETYESEIN 61 Query: 1059 NMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFE----------MNIPK 1108 ++EE S+ L +++ E L+ +V +D +I ELK E + + Sbjct: 62 LLKEENYEYSELLKETQDQAEFLKSVVIGKDKEIAELKSQNANDEIVKSRSRNGELQLAL 121 Query: 1109 TEGMIISSTIEPMS---DDAN-NVDXXXXXXXXXXXXLKVQEEEEFIQER--SVLQEQSA 1162 E + + ++ + DDA + L+V++ Q S LQ+++ Sbjct: 122 AENANLKNELQILQTKLDDAYLSKQVMDEQLQSLGQMLEVEQRNTLNQANQISTLQKEAQ 181 Query: 1163 KLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLN-------TENDNLLS 1215 L + + I+ E + G QE IN +KL ++ T+ND Sbjct: 182 YLRNSVNDRERFIVGKEKIIKLKDGEINRQQEIINDTLAKLAEMQHDNQVIVTQNDQYYK 241 Query: 1216 TVAELRSSISSAVDQRGFEIAELWKQH------------LAQREADFQKTEHELRVQLSA 1263 + E ++ I S DQ F +L + + Q Q+ E +L+ Q++ Sbjct: 242 LLQEKQAEIDSLKDQLQFFAEDLQRVQNYEGQYNDAQAKIKQLAQYIQELEKQLQDQMNQ 301 Query: 1264 FESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQ-NKLQDKEEHLRNLQEKYADVINQIEI 1322 +E + ++LL++ +++ E+ + I +E+ S + N+L+ + + + LQ++ D N+ + Sbjct: 302 YEKQIKELLNNAKATEDEKDHNIDQLEKDNSNKANQLEAQNKQISQLQKELKDADNKRD- 360 Query: 1323 LRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSX 1382 E++D + L N++ K ++ IN N +L + Sbjct: 361 --REVKDVQRKLDAELKKTAT--------LDKNNKTLKDKNDEQAKQINAANEELDQLDQ 410 Query: 1383 XXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLV 1442 ++ D E KV + +Q++ + EI E L Q N+ N+ Q+ Sbjct: 411 -----------KIADLEQKVKDQQNQIKDLEKEIKDLNKEKQ-NLIQDNN---NLHQKFN 455 Query: 1443 EYEKRIEDLTYEKESELAILRLKMHENANHYETMQK---ESEIERVKLIEELNVKITESV 1499 + E++ +++ +L + ++++ N+ E + K E E E +L +E+N + Sbjct: 456 QAEEK----ALQQQKDLVKAQKELNDKHNNAEQLNKDLDEYEQENKELQKEINSLNDQIN 511 Query: 1500 SLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVS 1559 LNK++ + K ++++ ++Q LE Q+ + + E LQ +++ + K ++ Sbjct: 512 QLNKEINQKQKQIDQQAKDIQKLQENLEKQKQDNQSKQQENKQLQQ----NNNDLNKQLN 567 Query: 1560 FASDTKQGRDEQLDNTMNKE 1579 + Q +Q++NT K+ Sbjct: 568 ESKKQNQKLQDQINNTEQKQ 587 >UniRef50_A0NCN7 Cluster: ENSANGP00000031886; n=1; Anopheles gambiae str. PEST|Rep: ENSANGP00000031886 - Anopheles gambiae str. PEST Length = 1029 Score = 127 bits (307), Expect = 2e-27 Identities = 197/905 (21%), Positives = 395/905 (43%), Gaps = 99/905 (10%) Query: 472 TEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIK--- 528 T + AK+ L+ +E + D +E+ + +T N E+D K + + Sbjct: 146 TSKASTDAKIAALLQSLDANEQNKAQLADNLEREMAKTRNLTSRNTELDVVKKQLTEELE 205 Query: 529 -VKSNHKLKLKQMQKTIDNF----SKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQL 583 VK++ +Q+++D ++++D+ ++ + T +L+ L++ ELE EK L Sbjct: 206 LVKTSMHESNAGLQRSLDALEHTKTQLADNLEQEMAKTADLNRLTE---ELEAEKKQLMQ 262 Query: 584 HLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDK 643 L M E +V K + EN AE + +++ +E K L D +E + Sbjct: 263 ELEIQKKQLMQELEVAKTSMS-ENNAELQ-RSLKAIEQTKMQLA----------DNLEKE 310 Query: 644 LADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDK 703 +A + L E++ L ++++ SK EN+ +L +++ +E K Sbjct: 311 IAKTADLNRRTEELEVEKKQLTQELEVAKTSKS------ENI----AELQRSLEAIEQTK 360 Query: 704 EDIMNKLQNYIQENMDLTDKLEKMSAEK---ISELLAKINHEEQSKIQTQFGIDAKIQER 760 + + L+ I + DL + EK+ EK + EL ++ + Q ++A Q + Sbjct: 361 LQLADNLEKEIAKTADLNRRTEKLEVEKKQLMQELEVAKTSMSENIAELQRSLEAIEQTK 420 Query: 761 DLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGS----YLQEKQKAYSEY 816 + +N+E E++K R EE + LE A GS LQ+ KA + Sbjct: 421 LQFADNLEKEIAKTADLNRRTEELEVEKKQLTQELE-VAKSSGSENIAELQQSLKAIEQT 479 Query: 817 TIQ-EDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQH 875 +Q D L +A D +R EK +E + +EL+ + E LQ SL ++Q Sbjct: 480 KLQLADNLEKEIAKTTDLNRRTEKLEVEKKQLMQELEVAKTSMSENIAELQQSLKAIEQT 539 Query: 876 Y-----NALVEKANRTDLAESESTKYQTQLRDLESNL---KRITHEHQTLIVQKKKEIED 927 N E A TDL + K + + + L L K E+ + + K IE Sbjct: 540 KLQLADNLEKEIAKTTDL-NRRTEKLEVEKKQLMQELEVAKTSMSENNAELQRSLKAIEL 598 Query: 928 LEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLE 987 +++ +E I LN + E E + + LQE + +++ N+ EL + Sbjct: 599 TKLQLADNLEKEIAKTADLNRRTE---ELEVEKKQLLQELEVAKTSMSENIAELQRSL-- 653 Query: 988 LIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIA-LNQKINNAQVSYMSMVSDY 1046 K +++ + Q D E+ I + +LN + K + E IA L + + + + + + + Sbjct: 654 ---KAIEQTKLQLADNLEKEIAKTAELNQVAKSSESENIAELQRSLEAIEQTKLQLADNL 710 Query: 1047 ESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNI 1106 E ++A+ T L EE++ KQLL +EL++ + + I EL+++ E Sbjct: 711 EKEIAK-TADLNRRTEELEVEKKQLL------QELEVAKTSKSESIAELQQSLEAIEQT- 762 Query: 1107 PKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNT 1166 + +++ +E + A D ++ +E E ++ + E +A+L Sbjct: 763 ----KLQLANNLE--KEIAKTADLNRRTEELEAEKKQLMQELEV--AKTSMSENNAELQR 814 Query: 1167 ELQEC-YTKIIQLETLNTELTGHDVVNQ--EQINQLKSKL-EQLNTENDNLLSTVAELRS 1222 L+ TK+ + L E+ +N+ E++ K +L ++L + +AEL+ Sbjct: 815 SLKAIEQTKLQLADNLEKEIAKTAELNRRTEELEVEKKQLTQELEVAKSSGSENIAELQQ 874 Query: 1223 SISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQ----------LSAFESKYEQLL 1272 S+ A++Q ++A+ ++ + + AD + EL V+ + + Q L Sbjct: 875 SL-KAIEQTKLQLADNLEKEIT-KTADLNRRTEELEVEKKQLTQELDDMKTTNASLRQSL 932 Query: 1273 DSVQSSTQEETNKI-VTMEQVTSLQNKLQDKEEHLRNLQEKYAD-----VINQIEILRSE 1326 + ++ + + TN + + + ++ LQ++L+ +E + L EK D ++ +I +L+ Sbjct: 933 EVLELTKTQITNSLELELVKIGDLQHQLKAMDE-AKTLAEKLGDSERSEMLAKISLLQQN 991 Query: 1327 IEDEK 1331 +E+E+ Sbjct: 992 LEEER 996 Score = 122 bits (293), Expect = 1e-25 Identities = 182/839 (21%), Positives = 358/839 (42%), Gaps = 49/839 (5%) Query: 298 QSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESK 357 +SIE EE + +E S E+ + K+ LE N ++ T + L +LA ++ Sbjct: 75 RSIEALEEELSRAKETASTEMERYRAMKKQYATLEEDNQLMKLTAEALREELAAKDGANQ 134 Query: 358 AVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSL 417 ++ K+ S +T +K+ + L + N+ + E+AK + S Sbjct: 135 NLAEALKEEF----ETSKASTDAKIAALLQSLDANEQNKAQLADNLEREMAKTRN-LTSR 189 Query: 418 NKDL-VDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVN 476 N +L V K+ + E + G + L EH + +L T D+N Sbjct: 190 NTELDVVKKQLTEELELVKTSMHESNAGLQRSLDAL--EHTKTQLADNLEQEMAKTADLN 247 Query: 477 EIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLK 536 + + E K++L E+ ++ K L+++L+ A+ +++ N E+ + K + + K Sbjct: 248 RLTEELEAEKKQLMQEL-EIQKKQLMQELEVAKTSMSENNAELQRSLKAIEQTKMQLADN 306 Query: 537 L-KQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIE 595 L K++ KT D + + E +LT+EL K ++ E LQ L + ++ Sbjct: 307 LEKEIAKTADLNRRTEELEVEKKQLTQELE--VAKTSK-SENIAELQRSLEAIEQTKLQL 363 Query: 596 SDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHI----LQQKYDEVEDKLADISQLQ 651 +D +K E+ A+ + LE +K L+QEL + + + E++ L I Q + Sbjct: 364 ADNLEK--EIAKTADLN-RRTEKLEVEKKQLMQELEVAKTSMSENIAELQRSLEAIEQTK 420 Query: 652 ---SDQVCSEI-KSVHLEEQIDALSASKKELALVIENLKLDKE----QLYGTIKDLENDK 703 +D + EI K+ L + + L KK+L +E K +L ++K +E K Sbjct: 421 LQFADNLEKEIAKTADLNRRTEELEVEKKQLTQELEVAKSSGSENIAELQQSLKAIEQTK 480 Query: 704 EDIMNKLQNYIQENMDLTDKLEKMSAEK---ISELLAKINHEEQSKIQTQFGIDAKIQER 760 + + L+ I + DL + EK+ EK + EL ++ + Q + A Q + Sbjct: 481 LQLADNLEKEIAKTTDLNRRTEKLEVEKKQLMQELEVAKTSMSENIAELQQSLKAIEQTK 540 Query: 761 DLYIENIESELSK---YKSRICRLE-ESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEY 816 +N+E E++K R +LE E +M++ + + + + LQ KA Sbjct: 541 LQLADNLEKEIAKTTDLNRRTEKLEVEKKQLMQELEVA-KTSMSENNAELQRSLKAIELT 599 Query: 817 TIQ-EDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQH 875 +Q D L +A D +R E+ +E + +EL+ + E LQ SL ++Q Sbjct: 600 KLQLADNLEKEIAKTADLNRRTEELEVEKKQLLQELEVAKTSMSENIAELQRSLKAIEQT 659 Query: 876 Y-----NALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEI 930 N E A +L + + + +L+ +L+ I L +KEI Sbjct: 660 KLQLADNLEKEIAKTAELNQVAKSSESENIAELQRSLEAIEQTKLQLADNLEKEIAK-TA 718 Query: 931 EFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNV-EELNKMNLELI 989 + N + E +KK L ++ E ++ A+LQ+ IE + + L K + Sbjct: 719 DLNRRTEELEVEKKQLLQELEVAKTSKSESIAELQQSLEAIEQTKLQLANNLEKEIAKTA 778 Query: 990 DKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESK 1049 D + + ++ ++ +Q + E+ + + + E+ + I ++ + +K Sbjct: 779 DLNRRTEELEAE--KKQLMQELEVAKTSMSENNAELQRSLKAIEQTKLQLADNLEKEIAK 836 Query: 1050 LAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPK 1108 A+ + E +E E ++++++L +K E + E +K +++TKL N+ K Sbjct: 837 TAELNRRTEELEVEKKQLTQELEVAKSSGSE---NIAELQQSLKAIEQTKLQLADNLEK 892 Score = 107 bits (256), Expect = 3e-21 Identities = 178/911 (19%), Positives = 385/911 (42%), Gaps = 75/911 (8%) Query: 237 QRLLKDIESKDVRISSL-EEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXL 295 ++L K +ESK+ I +L EE ++ E A E+ + Q Sbjct: 64 EQLQKQLESKNRSIEALEEELSRAKETASTEMERYRAMKKQYATLEEDNQLMKLTAEALR 123 Query: 296 AKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTE 355 + + + + K E + + K LL+ L+ Q +L + L + Sbjct: 124 EELAAKDGANQNLAEALKEEFETSKASTDAKIAALLQSLDAN-EQNKAQLADNLEREMAK 182 Query: 356 SKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQ 415 ++ ++S + + + +K +K+ S N + ++ E K ++ Sbjct: 183 TRNLTSRNTELD--VVKKQLTEELELVKT-----SMHESNAGLQRSLDALEHTKTQLA-- 233 Query: 416 SLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSL--IHVGTNTE 473 D +++E +++ K L+ +L+++ +Q M+ + + N Sbjct: 234 ----DNLEQE--MAKTADLNRLTEELEAEKKQLMQELEIQKKQLMQELEVAKTSMSENNA 287 Query: 474 DVNEIAKVQEQLKQELNDEI-KDV-NVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKS 531 ++ K EQ K +L D + K++ DL + + E + QL E++ A + + + Sbjct: 288 ELQRSLKAIEQTKMQLADNLEKEIAKTADLNRRTEELEVEKKQLTQELEVAKTSKSENIA 347 Query: 532 NHKLKLKQMQKT----IDNFSKVSDSNKEIVRLTEELH-HLSQKVAELEEEKGNLQLHLV 586 + L+ +++T DN K ++ R TE+L Q + ELE K ++ ++ Sbjct: 348 ELQRSLEAIEQTKLQLADNLEKEIAKTADLNRRTEKLEVEKKQLMQELEVAKTSMSENIA 407 Query: 587 DYDSGRMIESDVYKKMIEMENLAETRLKAISL------LESQKFDLVQELHILQ----QK 636 + R +E+ K+ +NL + K L LE +K L QEL + + + Sbjct: 408 ELQ--RSLEAIEQTKLQFADNLEKEIAKTADLNRRTEELEVEKKQLTQELEVAKSSGSEN 465 Query: 637 YDEVEDKLADISQLQ---SDQVCSEI-KSVHLEEQIDALSASKKELALVIENLKLDKE-- 690 E++ L I Q + +D + EI K+ L + + L KK+L +E K Sbjct: 466 IAELQQSLKAIEQTKLQLADNLEKEIAKTTDLNRRTEKLEVEKKQLMQELEVAKTSMSEN 525 Query: 691 --QLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQ 748 +L ++K +E K + + L+ I + DL + EK+ EK +L+ ++ + S + Sbjct: 526 IAELQQSLKAIEQTKLQLADNLEKEIAKTTDLNRRTEKLEVEK-KQLMQELEVAKTSMSE 584 Query: 749 TQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQE 808 +A++Q IE + +L+ LE+ IA D L R+ ++L E Sbjct: 585 N----NAELQRSLKAIELTKLQLAD------NLEKEIAKTAD----LNRRTEELE---VE 627 Query: 809 KQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEI-EHENKELQKKNQILLEENQNLQI 867 K++ E + + + +A L + +E+ L++ ++ KE+ K ++ + Sbjct: 628 KKQLLQELEVAKTSMSENIAELQRSLKAIEQTKLQLADNLEKEIAKTAELNQVAKSSESE 687 Query: 868 SLSDMQQHYNALVE-KANRTDLAESESTK---YQTQLRDLESNLKRITHEHQTLIVQKKK 923 +++++Q+ A+ + K D E E K + +LE K++ E + K + Sbjct: 688 NIAELQRSLEAIEQTKLQLADNLEKEIAKTADLNRRTEELEVEKKQLLQELEVAKTSKSE 747 Query: 924 EIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEY---VTQLEAQLQEYKNNIENLNMNVEE 980 I +L+ ++ ++ L ++ K + +LEA+ ++ +E ++ E Sbjct: 748 SIAELQQSLEAIEQTKLQLANNLEKEIAKTADLNRRTEELEAEKKQLMQELEVAKTSMSE 807 Query: 981 LNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYM 1040 N L+ K +++ + Q D E+ I + +LN ++ + E L Q++ A+ S Sbjct: 808 -NNAELQRSLKAIEQTKLQLADNLEKEIAKTAELNRRTEELEVEKKQLTQELEVAKSSGS 866 Query: 1041 SMVSDYESKL-AQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETK 1099 +++ + L A TKL+ + + +++ + D + EEL++ ++ ++ ++K T Sbjct: 867 ENIAELQQSLKAIEQTKLQ-LADNLEKEITKTADLNRRTEELEVEKKQLTQELDDMKTTN 925 Query: 1100 LTFEMNIPKTE 1110 + ++ E Sbjct: 926 ASLRQSLEVLE 936 Score = 105 bits (252), Expect = 1e-20 Identities = 202/965 (20%), Positives = 389/965 (40%), Gaps = 93/965 (9%) Query: 621 SQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELAL 680 SQ+ + Q L +Q+ +E LA IS L+ + C V + + +D L+ L Sbjct: 10 SQERQIEQLLQSVQELQEEKRRNLAKISALELKEAC-----VCMSDAVDYLA---HPLGR 61 Query: 681 VIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSA--EKISELLAK 738 E L+ E +I+ LE + +++ + M+ ++K A E+ ++L+ Sbjct: 62 ATEQLQKQLESKNRSIEALEEE----LSRAKETASTEMERYRAMKKQYATLEEDNQLMKL 117 Query: 739 INHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERK 798 + ++ + G + + E E E+ + ++I L +S+ E + K Sbjct: 118 TAEALREELAAKDGANQNLAEA--LKEEFETSKASTDAKIAALLQSLDANE------QNK 169 Query: 799 ADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQIL 858 A QL L+ + T + EL VV+KQL E EL+ + Sbjct: 170 A-QLADNLEREMAKTRNLTSRNTEL-----------DVVKKQLTE------ELELVKTSM 211 Query: 859 LEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLI 918 E N LQ SL ++ L + + ++A++ T+ +LE+ K++ E L Sbjct: 212 HESNAGLQRSLDALEHTKTQLADNLEQ-EMAKTADLNRLTE--ELEAEKKQLMQE---LE 265 Query: 919 VQKKKEIEDLEI------EFNTQIESAIR----DKKVLNEKYEKNIEYVTQLEAQLQEYK 968 +QKK+ +++LE+ E N +++ +++ K L + EK I L + +E + Sbjct: 266 IQKKQLMQELEVAKTSMSENNAELQRSLKAIEQTKMQLADNLEKEIAKTADLNRRTEELE 325 Query: 969 NNIENLNMNVEELNKMNLELIDK------HVQKQQTQSPDYTEQYINEINKLNALLKQKD 1022 + L +E E I + +++ + Q D E+ I + LN ++ + Sbjct: 326 VEKKQLTQELEVAKTSKSENIAELQRSLEAIEQTKLQLADNLEKEIAKTADLNRRTEKLE 385 Query: 1023 EEIIALNQKINNAQVSYMSMVSDYESKLAQFT-TKLENMEEEMQRVSKQLLDSKQHNEEL 1081 E L Q++ A+ S +++ + L TKL+ + + ++K D + EEL Sbjct: 386 VEKKQLMQELEVAKTSMSENIAELQRSLEAIEQTKLQFADNLEKEIAKTA-DLNRRTEEL 444 Query: 1082 QILVREQDDQIKELKETKLTFEMNIPKTEGMI--ISSTIEPMSDDANNVDXXXXXXXXXX 1139 ++ E+ +EL+ K + NI + + + I T ++D+ Sbjct: 445 EV---EKKQLTQELEVAKSSGSENIAELQQSLKAIEQTKLQLADNLEKEIAKTTDLNRRT 501 Query: 1140 XXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQL 1199 L+V E+++ +QE V + ++ ELQ+ I Q + + ++ +N+ Sbjct: 502 EKLEV-EKKQLMQELEVAKTSMSENIAELQQSLKAIEQTKLQLADNLEKEIAKTTDLNRR 560 Query: 1200 KSKLEQLNTENDNLLSTVAELRSSIS--SAVDQRGFEIAELWKQHLAQ-------READF 1250 KLE E L+ + ++S+S +A QR + EL K LA + AD Sbjct: 561 TEKLE---VEKKQLMQELEVAKTSMSENNAELQRSLKAIELTKLQLADNLEKEIAKTADL 617 Query: 1251 QKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVT-SLQNKLQDKEEHLRNL 1309 + EL V+ + E S+ + E + +EQ L + L+ + L Sbjct: 618 NRRTEELEVEKKQLLQELEVAKTSMSENIAELQRSLKAIEQTKLQLADNLEKEIAKTAEL 677 Query: 1310 QE--KYADVINQIEILRS--EIEDEKVAFXXXXXXXXXXXXXX---XXDLRTENQSYKQM 1362 + K ++ N E+ RS IE K+ +L E + Q Sbjct: 678 NQVAKSSESENIAELQRSLEAIEQTKLQLADNLEKEIAKTADLNRRTEELEVEKKQLLQE 737 Query: 1363 QEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHE 1422 E + + +E A+L++S + AK +L + E ++E Q E Sbjct: 738 LEVAKTSKSESIAELQQSLEAIEQTKLQLANNLEKEIAKTADLNRRTEELEAEKKQLMQE 797 Query: 1423 YTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELA-ILRLKMHENANHYETMQKESE 1481 + T ++ +++ L E+ L E E+A L E Q E Sbjct: 798 LEVAKTSMSENNAELQRSLKAIEQTKLQLADNLEKEIAKTAELNRRTEELEVEKKQLTQE 857 Query: 1482 IERVKLIEELNV-KITESVSLNKQVA-ELNKALEEEVAKTNEMQTALENQEIEIVTLNDE 1539 +E K N+ ++ +S+ +Q +L LE+E+ KT ++ E E+E L E Sbjct: 858 LEVAKSSGSENIAELQQSLKAIEQTKLQLADNLEKEITKTADLNRRTEELEVEKKQLTQE 917 Query: 1540 ITNLQ 1544 + +++ Sbjct: 918 LDDMK 922 Score = 99.1 bits (236), Expect = 9e-19 Identities = 164/848 (19%), Positives = 351/848 (41%), Gaps = 66/848 (7%) Query: 764 IENIESELSKYKSRICRLE--ESIAVMEDR----RYSLERKADQLGSYLQEKQKAYSEYT 817 ++ ++ E + ++I LE E+ M D + L R +QL L+ K ++ Sbjct: 22 VQELQEEKRRNLAKISALELKEACVCMSDAVDYLAHPLGRATEQLQKQLESKNRSIEALE 81 Query: 818 IQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEE-------NQNLQISLS 870 + + M+ R ++KQ +E +N+ ++ + L EE NQNL +L Sbjct: 82 EELSRAKETASTEMERYRAMKKQYATLEEDNQLMKLTAEALREELAAKDGANQNLAEALK 141 Query: 871 DMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEI 930 + + A + A L +S Q + + L NL+R + + L + E++ ++ Sbjct: 142 EEFETSKASTD-AKIAALLQSLDANEQNKAQ-LADNLEREMAKTRNL-TSRNTELDVVKK 198 Query: 931 EFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELID 990 + ++E N +++++ + + QL + N+E +LN++ EL Sbjct: 199 QLTEELELVKTSMHESNAGLQRSLDALEHTKTQLAD---NLEQEMAKTADLNRLTEELEA 255 Query: 991 KHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKL 1050 + Q Q + +Q + E+ + + + E L + + + + M + + E ++ Sbjct: 256 EKKQLMQ-ELEIQKKQLMQELEVAKTSMSENNAE---LQRSLKAIEQTKMQLADNLEKEI 311 Query: 1051 AQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTE 1110 A+ T L EE++ ++ KQ +EL++ + + I EL+ + E Sbjct: 312 AK-TADLNRRTEELE------VEKKQLTQELEVAKTSKSENIAELQRSLEAIEQT----- 359 Query: 1111 GMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQE 1170 + ++ +E + A D ++ +E E ++ + E A+L L+ Sbjct: 360 KLQLADNLE--KEIAKTADLNRRTEKLEVEKKQLMQELEVA--KTSMSENIAELQRSLEA 415 Query: 1171 C-YTKIIQLETLNTELTGHDVVNQ--EQINQLKSKLEQ-LNTENDNLLSTVAELRSSISS 1226 TK+ + L E+ +N+ E++ K +L Q L + +AEL+ S+ Sbjct: 416 IEQTKLQFADNLEKEIAKTADLNRRTEELEVEKKQLTQELEVAKSSGSENIAELQQSLK- 474 Query: 1227 AVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKI 1286 A++Q ++A+ ++ +A + D + +L V+ + E S+ + E + Sbjct: 475 AIEQTKLQLADNLEKEIA-KTTDLNRRTEKLEVEKKQLMQELEVAKTSMSENIAELQQSL 533 Query: 1287 VTMEQVT-SLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXX 1345 +EQ L + L+ + +L + + + + L E+E K + Sbjct: 534 KAIEQTKLQLADNLEKEIAKTTDLNRRTEKLEVEKKQLMQELEVAKTSMSENNAELQRSL 593 Query: 1346 XXXX-XDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEA-KVL 1403 L+ + K++ + + LN E +++K N AE + L Sbjct: 594 KAIELTKLQLADNLEKEIAKTADLNRRTEELEVEKKQLLQELEVAKTSMSENIAELQRSL 653 Query: 1404 ELTHQLELKDSEIYQKTHEYTITLTQ--RNDEFENVRQQLVEYEKRIEDLTYEKESELAI 1461 + Q +L+ ++ +K T L Q ++ E EN+ E ++ +E + K Sbjct: 654 KAIEQTKLQLADNLEKEIAKTAELNQVAKSSESENI----AELQRSLEAIEQTKLQLADN 709 Query: 1462 LRLKMHENANHYETMQKESEIERVKLIEELNVKIT---ESVSLNKQVAE--------LNK 1510 L ++ + A+ +E E+E+ +L++EL V T ES++ +Q E L Sbjct: 710 LEKEIAKTAD-LNRRTEELEVEKKQLLQELEVAKTSKSESIAELQQSLEAIEQTKLQLAN 768 Query: 1511 ALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDE 1570 LE+E+AKT ++ E E E L E+ + + +++++Q+ + TK + Sbjct: 769 NLEKEIAKTADLNRRTEELEAEKKQLMQELEVAKTSMSENNAELQRSLKAIEQTKLQLAD 828 Query: 1571 QLDNTMNK 1578 L+ + K Sbjct: 829 NLEKEIAK 836 Score = 81.8 bits (193), Expect = 1e-13 Identities = 158/747 (21%), Positives = 315/747 (42%), Gaps = 65/747 (8%) Query: 212 EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRIS-SLE-EANKLLEAARF--EI 267 E K+Q+T+ E ++E E QR L+ IE ++++ +LE E K + R ++ Sbjct: 325 EVEKKQLTQELEVAKTSKSENIAELQRSLEAIEQTKLQLADNLEKEIAKTADLNRRTEKL 384 Query: 268 SLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKK 327 +E +L QELE ++S+E + K + + EIA +L ++ Sbjct: 385 EVEKKQLMQELEVAKTSMSENIAEL----QRSLEAIEQTKLQFADNLEKEIAKTADLNRR 440 Query: 328 IELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWS 387 E LE + +Q +ELE ++ G+E+ A S K + N ++ + Sbjct: 441 TEELE---VEKKQLTQELEVAKSS-GSENIAELQQSLKAIEQTKLQLADNLEKEIAKT-T 495 Query: 388 QLSSETLNQDTDKK--INKNEIAKLEMV--IQSLNKDLVDKEYVISEKDTXXXXXXXXXX 443 L+ T + +KK + + E+AK M I L + L E + Sbjct: 496 DLNRRTEKLEVEKKQLMQELEVAKTSMSENIAELQQSLKAIEQTKLQLADNLEKEIAKTT 555 Query: 444 GKDTLIAQLQLEHQQHMEGPSLIH--VGTNTEDVNEIAKVQEQLKQELNDEIKDVNVK-- 499 + +L++E +Q M+ + + N ++ K E K +L D ++ K Sbjct: 556 DLNRRTEKLEVEKKQLMQELEVAKTSMSENNAELQRSLKAIELTKLQLADNLEKEIAKTA 615 Query: 500 DLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVR 559 DL + + E + QL E++ A +M + + + LK +++T + KEI + Sbjct: 616 DLNRRTEELEVEKKQLLQELEVAKTSMSENIAELQRSLKAIEQT--KLQLADNLEKEIAK 673 Query: 560 LTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLL 619 T EL+ ++ K +E E LQ L + ++ +D +K E+ A+ + L Sbjct: 674 -TAELNQVA-KSSE-SENIAELQRSLEAIEQTKLQLADNLEK--EIAKTADLNRRTEEL- 727 Query: 620 ESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELA 679 E +K L+QEL + + E I++LQ E + L ++ A +L Sbjct: 728 EVEKKQLLQELEVAKTSKSE------SIAELQQSLEAIEQTKLQLANNLEKEIAKTADLN 781 Query: 680 LVIENLKLDKEQLYGTIK----DLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISEL 735 E L+ +K+QL ++ + + ++ L+ Q + L D LEK A+ Sbjct: 782 RRTEELEAEKKQLMQELEVAKTSMSENNAELQRSLKAIEQTKLQLADNLEKEIAK----- 836 Query: 736 LAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSL 795 A++N + + +++++ L + +E S I L++S+ +E + L Sbjct: 837 TAELNRRTE---------ELEVEKKQL-TQELEVAKSSGSENIAELQQSLKAIEQTKLQL 886 Query: 796 ERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKN 855 ++ + + + E +++ +L L + + + +Q LE+ E + Q N Sbjct: 887 ADNLEKEITKTADLNRRTEELEVEKKQLTQELDDMKTTNASL-RQSLEV-LELTKTQITN 944 Query: 856 QILLEENQNLQISLSDMQQHYNALVE-KANRTDLAESESTKYQTQLRDLESNLKRITHEH 914 + LE + + D+Q A+ E K L +SE ++ ++ L+ NL+ + Sbjct: 945 SLELE-----LVKIGDLQHQLKAMDEAKTLAEKLGDSERSEMLAKISLLQQNLEEEREKS 999 Query: 915 QTLIVQ---KKKEIEDLEIEFNTQIES 938 + Q K++ +DL+ + ++S Sbjct: 1000 DEINCQYLAMKRQADDLDAQCTKLMKS 1026 Score = 71.7 bits (168), Expect = 2e-10 Identities = 127/637 (19%), Positives = 243/637 (38%), Gaps = 36/637 (5%) Query: 947 NEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQ 1006 N E+ IE + Q +LQE K N+ +++ + L K + + DY Sbjct: 8 NTSQERQIEQLLQSVQELQEEKRR------NLAKISALEL----KEACVCMSDAVDYLAH 57 Query: 1007 YINEINK-LNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQ 1065 + + L L+ K+ I AL ++++ A+ + + + Y + Q+ T +EE+ Q Sbjct: 58 PLGRATEQLQKQLESKNRSIEALEEELSRAKETASTEMERYRAMKKQYAT----LEEDNQ 113 Query: 1066 RVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDA 1125 + L ++ EEL + + LKE FE + T+ I + S DA Sbjct: 114 LMK---LTAEALREELAAKDGANQNLAEALKEE---FETSKASTDAKIAALL---QSLDA 164 Query: 1126 NNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTEL 1185 N + K + E V+++Q L EL+ T + N L Sbjct: 165 NEQNKAQLADNLEREMAKTRNLTSRNTELDVVKKQ---LTEELELVKTS---MHESNAGL 218 Query: 1186 TGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQ 1245 + QL LEQ + +L EL + + + + +L Q L Sbjct: 219 QRSLDALEHTKTQLADNLEQEMAKTADLNRLTEELEAEKKQLMQELEIQKKQLM-QELEV 277 Query: 1246 READFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKL-QDKEE 1304 + + EL+ L A E QL D+++ + + E++ + +L Q+ E Sbjct: 278 AKTSMSENNAELQRSLKAIEQTKMQLADNLEKEIAKTADLNRRTEELEVEKKQLTQELEV 337 Query: 1305 HLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQE 1364 + E A++ +E + + + + L E + Q E Sbjct: 338 AKTSKSENIAELQRSLEAIE-QTKLQLADNLEKEIAKTADLNRRTEKLEVEKKQLMQELE 396 Query: 1365 QSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYT 1424 + +++E A+L++S + AK +L + E + E Q T E Sbjct: 397 VAKTSMSENIAELQRSLEAIEQTKLQFADNLEKEIAKTADLNRRTEELEVEKKQLTQELE 456 Query: 1425 ITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELA-ILRLKMHENANHYETMQKESEIE 1483 + + ++ ++Q L E+ L E E+A L E Q E+E Sbjct: 457 VAKSSGSENIAELQQSLKAIEQTKLQLADNLEKEIAKTTDLNRRTEKLEVEKKQLMQELE 516 Query: 1484 RVKLIEELNV-KITESVSLNKQVA-ELNKALEEEVAKTNEMQTALENQEIEIVTLNDEIT 1541 K N+ ++ +S+ +Q +L LE+E+AKT ++ E E+E L E+ Sbjct: 517 VAKTSMSENIAELQQSLKAIEQTKLQLADNLEKEIAKTTDLNRRTEKLEVEKKQLMQELE 576 Query: 1542 NLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNK 1578 + + +++++Q+ + TK + L+ + K Sbjct: 577 VAKTSMSENNAELQRSLKAIELTKLQLADNLEKEIAK 613 >UniRef50_A2DGV9 Cluster: Viral A-type inclusion protein, putative; n=1; Trichomonas vaginalis G3|Rep: Viral A-type inclusion protein, putative - Trichomonas vaginalis G3 Length = 1150 Score = 127 bits (306), Expect = 3e-27 Identities = 216/1079 (20%), Positives = 471/1079 (43%), Gaps = 78/1079 (7%) Query: 473 EDVNEIAKVQEQLKQELNDE-IKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKS 531 + + E+ K Q Q+ EL + I D N + + S T + E N+ V Sbjct: 49 QSLYELFKQQIQMYNELKEAYINDTNSYSVT--ITSINNLYTYIQQEFGQKVDNIDSVLK 106 Query: 532 NHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSG 591 K K+K +++D +I +L E HL K+ E ++ G+L+ + Sbjct: 107 IFKEKVKSSNESVDLQKNEKSLKHQIKKLQRENSHLQDKLNE-RDKSGDLRRKI------ 159 Query: 592 RMIESDVYKKMIEMENLAETRLKAISLLESQKFD---LVQELHILQQK-YDEVEDKLADI 647 + +++D+ K E++ L T + E QK D L + H LQ+ V+ K +I Sbjct: 160 QSLKNDMDSKETEIKQLNSTLKEIKQKFEKQKQDNEKLRNDYHELQETVVTSVDTKTEEI 219 Query: 648 SQLQSDQVCSEIKSVHLE-EQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDI 706 D S++ + E EQ+ + ++ A ++L++ +E + T K LE ++ + Sbjct: 220 R--PDDIRMSQLSQLQRENEQLQHKISILEDEAQ--KSLEISQEDMKKT-KGLEKSQQIL 274 Query: 707 MNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIEN 766 ++L + ++ +L ++L +++ +K + + ++ + + +D K E + I Sbjct: 275 QSQLDDANEDIKNLNEEL-RLANQKTQSIEKSMRSLQRENSELKAKLDEKDAEHETTISE 333 Query: 767 IESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDEL--V 824 ++ E++K S I ++ + +ED + + R D+L +E + SE + ++ Sbjct: 334 MKGEIAKSDSNIRKIASLNSKIEDYQEEITRINDELAQTHEELRTVTSENARLKTKVGEF 393 Query: 825 NRLAVLMDHDRVVEKQLLEIEHENKELQKK-NQILLEENQNLQISLSDMQQHYNALVEKA 883 R A L+ +R ++Q +E EN L+ K N+ L+ Q+++ + ++ ++ + E Sbjct: 394 ERRASLLS-ERPSKEQFTVLEEENARLKSKINENQLKYQQSIETAQNENKELKQTISEIQ 452 Query: 884 NRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEI---EFNTQIESAI 940 N+T E T ++ + D LKRI E +L Q K +D +I + T E A Sbjct: 453 NQTVQITKEKTSFEQENND----LKRIAGEVDSLKQQIKSLKQDNDILKDKLQTAEEKAS 508 Query: 941 RDKKVLN--EKYEKNIEYVTQ-LEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQ 997 +K + E+ + + + Q + +++KN+I L +L + +L D+ KQ Sbjct: 509 NTQKAQSSFERLQNDYRNLKQEVNENTEKHKNSISQLKKENSQLKETIEDLEDQIHAKQN 568 Query: 998 T--QSPDYTEQYINEINKLNA-------LLKQKDEEIIALNQKINNAQVSYMSMVSDYES 1048 + + N I +L++ LL++K E L Q +AQ S + S + Sbjct: 569 SLDREKSNNNNLRNTIEELHSKSLENSRLLEKKKAENEDLKQSYEDAQ-SKSIISSSQQR 627 Query: 1049 KLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPK 1108 + + + + E ++ + QL ++ + +Q L + +++++K E+K + + Sbjct: 628 SIDRLRNENNELRETIEDLQNQLGNNGSQTKTIQKL-KAENEELKAEMESKQNRSLERLR 686 Query: 1109 TEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTEL 1168 E + I + D + V+E QE L++QS + Sbjct: 687 NENRQLKQEIADL-DSKYQLSQSQLQST-------VKENAGLKQEIEDLEDQS------M 732 Query: 1169 QECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAV 1228 Q +I +L+ N +L + +++ Q N+ ++L+ EN++L T+ EL+S +S ++ Sbjct: 733 QNVSKEIDRLKNENLDL--KEKIDRLQNNRSSARLK---AENEDLKQTIEELKSQMSKSI 787 Query: 1229 DQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVT 1288 D E EL +++ EA K + + + ++L + S ++ + K Sbjct: 788 DNLKSENRELRRKNSDLVEATQIKPTDVDQDTIEQLTRENDELRRKL-SLSKNDNEKSNL 846 Query: 1289 MEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXX 1348 +EQVT+L+ K + +R++ E A+ N + ++ ++ D + Sbjct: 847 IEQVTTLKEKNIELLMKMRDMMED-AENGNNNDQMKRQVSDLQRQNADLQRQLSESQRIL 905 Query: 1349 XXDLRTENQSYKQMQEQSILNINE------ENAQLKKSSXXXXXXXXXXXXRVNDAEAKV 1402 + + ++ + + +++I I+E E LK+S + D Sbjct: 906 DNERQKKSVNDDTIDQKTIKLISENREMKLEIESLKRSISDYEKLIDFERQKRYDNSDDK 965 Query: 1403 LELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAIL 1462 +++ ++ +++++ + + L+++ + ++VR+++ E ++ + E S Sbjct: 966 SKISRLID-ENNDLRSVIKDLNLKLSEKKEFADSVRRRIESIEAKVGYVANEFSSYKQRK 1024 Query: 1463 RLKMHENANHYET---MQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAK 1518 + + N N+ E +QKE++ V L+ +L +I ++ Q K+L E K Sbjct: 1025 SSQYNGNENNSEEVRYLQKENQ-RLVSLVSKLKCEIIGIRNIAAQQISSKKSLSPEEIK 1082 Score = 110 bits (265), Expect = 3e-22 Identities = 196/1040 (18%), Positives = 441/1040 (42%), Gaps = 124/1040 (11%) Query: 589 DSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADIS 648 +S + +E+ + K+ ++E T K S F ++Q L+ L ++ ++ ++L + Sbjct: 12 ESFKQLEAQISKQTQDIEEFISTHSKYHK--PSHTFQVLQSLYELFKQQIQMYNELKEAY 69 Query: 649 QLQSDQVCSEIKSVHLEEQIDALSASKKELALVIEN----LKLDKEQLYGTIK--DLEND 702 ++ I S++ + + ++E ++N LK+ KE++ + + DL+ + Sbjct: 70 INDTNSYSVTITSIN-----NLYTYIQQEFGQKVDNIDSVLKIFKEKVKSSNESVDLQKN 124 Query: 703 KEDIMNKLQNYIQENMDLTDKL-EKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERD 761 ++ + ++++ +EN L DKL E+ + + + + ++ SK +++ ++E Sbjct: 125 EKSLKHQIKKLQRENSHLQDKLNERDKSGDLRRKIQSLKNDMDSKETEIKQLNSTLKEIK 184 Query: 762 LYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQED 821 E + + K ++ L+E++ D + R D S L + Q+ + + Sbjct: 185 QKFEKQKQDNEKLRNDYHELQETVVTSVDTKTEEIRPDDIRMSQLSQLQR-------ENE 237 Query: 822 ELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVE 881 +L +++++L D ++ LEI E+ KK + L + Q LQ L D + L E Sbjct: 238 QLQHKISILEDE----AQKSLEISQED---MKKTKGLEKSQQILQSQLDDANEDIKNLNE 290 Query: 882 K---AN-RTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIE 937 + AN +T E Q + +L++ L EH+T I + K EI + + Sbjct: 291 ELRLANQKTQSIEKSMRSLQRENSELKAKLDEKDAEHETTISEMKGEI--------AKSD 342 Query: 938 SAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQ 997 S IR LN K E E +T++ +L + + + L + + ++ Sbjct: 343 SNIRKIASLNSKIEDYQEEITRINDELAQTHEELRTVTSENARLKTK----VGEFERRAS 398 Query: 998 TQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKL 1057 S +++ + + NA LK K IN Q+ Y + +++ + + Sbjct: 399 LLSERPSKEQFTVLEEENARLKSK----------INENQLKYQQSIETAQNENKELKQTI 448 Query: 1058 ENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISST 1117 ++ + +++K+ +Q N +L+ + E D +++K K + I+ Sbjct: 449 SEIQNQTVQITKEKTSFEQENNDLKRIAGEVDSLKQQIKSL---------KQDNDILKDK 499 Query: 1118 IEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQ 1177 ++ + A+N K Q E +Q +Q NTE + I Q Sbjct: 500 LQTAEEKASNTQ-------------KAQSSFERLQNDYRNLKQEVNENTEKHK--NSISQ 544 Query: 1178 LETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSI---SSAVDQRGFE 1234 L+ N++L ++QI+ ++ L++ + N+NL +T+ EL S S ++++ E Sbjct: 545 LKKENSQLKETIEDLEDQIHAKQNSLDREKSNNNNLRNTIEELHSKSLENSRLLEKKKAE 604 Query: 1235 IAELWKQHL-AQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVT 1293 +L + + AQ ++ ++ +L ++ + ++ +Q+ ++ T++++ Sbjct: 605 NEDLKQSYEDAQSKSIISSSQQRSIDRLRNENNELRETIEDLQNQLGNNGSQTKTIQKLK 664 Query: 1294 S----LQNKLQDKE----EHLRN----LQEKYADVINQIEILRSEIEDE-------KVAF 1334 + L+ +++ K+ E LRN L+++ AD+ ++ ++ +S+++ K Sbjct: 665 AENEELKAEMESKQNRSLERLRNENRQLKQEIADLDSKYQLSQSQLQSTVKENAGLKQEI 724 Query: 1335 XXXXXXXXXXXXXXXXDLRTENQSYKQ-----MQEQSILNINEENAQLKKSSXXXXXXXX 1389 L+ EN K+ +S + EN LK++ Sbjct: 725 EDLEDQSMQNVSKEIDRLKNENLDLKEKIDRLQNNRSSARLKAENEDLKQTIEELKSQMS 784 Query: 1390 XXXXRV----NDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFE---NVRQQLV 1442 + + K +L ++K +++ Q T E LT+ NDE ++ + Sbjct: 785 KSIDNLKSENRELRRKNSDLVEATQIKPTDVDQDTIE---QLTRENDELRRKLSLSKNDN 841 Query: 1443 EYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLN 1502 E IE +T KE + +L +KM + E +++R + +L ++ L Sbjct: 842 EKSNLIEQVTTLKEKNIELL-MKMRDMMEDAENGNNNDQMKR--QVSDLQ---RQNADLQ 895 Query: 1503 KQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFAS 1562 +Q++E + L+ E K + ++ + I++++ N E+ ++ S S +K + F Sbjct: 896 RQLSESQRILDNERQKKSVNDDTIDQKTIKLISENREMKLEIESLKRSISDYEKLIDF-- 953 Query: 1563 DTKQGRDEQLDNTMNKELLD 1582 + ++ D D + L+D Sbjct: 954 ERQKRYDNSDDKSKISRLID 973 Score = 110 bits (264), Expect = 4e-22 Identities = 178/981 (18%), Positives = 430/981 (43%), Gaps = 94/981 (9%) Query: 161 LQVKMKIMETTILDLQEKINEKDQI--IEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQM 218 L+ ++K ++ LQ+K+NE+D+ + K ++ ++ KQ+ Sbjct: 128 LKHQIKKLQRENSHLQDKLNERDKSGDLRRKIQSLKNDMDSKETEIKQLNSTLKEIKQKF 187 Query: 219 TKMQENFIAMEAEWKDEKQRLLKDIESK-------DVRISSLEEANKLLEAARFEISL-- 269 K +++ + ++ + ++ ++ +++K D+R+S L + + E + +IS+ Sbjct: 188 EKQKQDNEKLRNDYHELQETVVTSVDTKTEEIRPDDIRMSQLSQLQRENEQLQHKISILE 247 Query: 270 EHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIE 329 + ++ + E+ Q + + ++ + E+ + E+ L + K + Sbjct: 248 DEAQKSLEISQEDMKKTKGLEKSQQILQSQLDDANEDIKNLNEELRLANQKTQSIEKSMR 307 Query: 330 LLEHLNCQIR----QTNKELENKLATMGTESKAVSSPSKKGSPLISR-KSGRNTASKMKS 384 L+ N +++ + + E E ++ M E S +K + L S+ + + +++ Sbjct: 308 SLQRENSELKAKLDEKDAEHETTISEMKGEIAKSDSNIRKIASLNSKIEDYQEEITRIND 367 Query: 385 PWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXG 444 +Q E ++ K ++ + E L++ +++ + E++ Sbjct: 368 ELAQTHEELRTVTSENARLKTKVGEFERRASLLSERPSKEQFTVLEEENARL-------- 419 Query: 445 KDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQ----LKQELNDEIKDVNVKD 500 + I + QL++QQ +E N E I+++Q Q K++ + E ++ ++K Sbjct: 420 -KSKINENQLKYQQSIETAQ----NENKELKQTISEIQNQTVQITKEKTSFEQENNDLKR 474 Query: 501 LIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVR- 559 + ++ S ++QI L + D + + K QK +F ++ + + + + Sbjct: 475 IAGEVDSLKQQIKSLKQDNDILKDKLQTAEE----KASNTQKAQSSFERLQNDYRNLKQE 530 Query: 560 LTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLL 619 + E +++L++E L+ + D +E ++ K ++ + + Sbjct: 531 VNENTEKHKNSISQLKKENSQLKETIED------LEDQIHAKQNSLDREKSNNNNLRNTI 584 Query: 620 ESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELA 679 E ++ +L++K E E D+ Q D I S + ID L EL Sbjct: 585 EELHSKSLENSRLLEKKKAENE----DLKQSYEDAQSKSIISSSQQRSIDRLRNENNELR 640 Query: 680 LVIENLKL---DKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELL 736 IE+L+ + TI+ L+ + E++ ++++ +++ + ++I++L Sbjct: 641 ETIEDLQNQLGNNGSQTKTIQKLKAENEELKAEMESKQNRSLERLRNENRQLKQEIADLD 700 Query: 737 AKINHEE---QSKIQTQFGIDAKIQE-RDLYIENIESELSKYKSRICRLEESIAVMEDRR 792 +K + QS ++ G+ +I++ D ++N+ E+ + K+ L+E I +++ R Sbjct: 701 SKYQLSQSQLQSTVKENAGLKQEIEDLEDQSMQNVSKEIDRLKNENLDLKEKIDRLQNNR 760 Query: 793 YSLERKA--DQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKE 850 S KA + L ++E + S+ +I + NR + D V Q+ + + Sbjct: 761 SSARLKAENEDLKQTIEELKSQMSK-SIDNLKSENRELRRKNSDLVEATQIKPTDVDQDT 819 Query: 851 LQKKNQILLEENQNL--QISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLK 908 +++ L EN L ++SLS + L+E+ T L E ++ + ++RD+ + + Sbjct: 820 IEQ----LTRENDELRRKLSLSKNDNEKSNLIEQV--TTLKE-KNIELLMKMRDMMEDAE 872 Query: 909 RITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRD-KKVL-NEKYEKNI------EYVTQL 960 + Q K+++ DL+ + N ++ + + +++L NE+ +K++ + +L Sbjct: 873 NGNNND-----QMKRQVSDLQRQ-NADLQRQLSESQRILDNERQKKSVNDDTIDQKTIKL 926 Query: 961 EAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTE--QYINEINKLNALL 1018 ++ +E K IE+L ++ + K LID QK+ S D ++ + I+E N L +++ Sbjct: 927 ISENREMKLEIESLKRSISDYEK----LIDFERQKRYDNSDDKSKISRLIDENNDLRSVI 982 Query: 1019 KQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHN 1078 K + + L++K A S + E+K+ + + + QR S Q ++ ++ Sbjct: 983 KDLN---LKLSEKKEFAD-SVRRRIESIEAKVGYVANEFSSYK---QRKSSQYNGNENNS 1035 Query: 1079 EELQILVREQDDQIKELKETK 1099 EE++ L +E + + + K Sbjct: 1036 EEVRYLQKENQRLVSLVSKLK 1056 Score = 108 bits (260), Expect = 1e-21 Identities = 197/985 (20%), Positives = 420/985 (42%), Gaps = 87/985 (8%) Query: 390 SSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLI 449 S+E+++ ++K K++I KL+ L L +++ + K+T I Sbjct: 115 SNESVDLQKNEKSLKHQIKKLQRENSHLQDKLNERDKS-GDLRRKIQSLKNDMDSKETEI 173 Query: 450 AQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDL-IEKLKSA 508 QL ++ ++ N + N+ ++QE + ++ + +++ D+ + +L Sbjct: 174 KQLNSTLKE-IKQKFEKQKQDNEKLRNDYHELQETVVTSVDTKTEEIRPDDIRMSQLSQL 232 Query: 509 EEQITQLNDEI----DAANKNMIKVKSNHKLKLKQMQKTIDNF-SKVSDSNKEIVRLTEE 563 + + QL +I D A K++ ++ K K ++K+ S++ D+N++I L EE Sbjct: 233 QRENEQLQHKISILEDEAQKSL-EISQEDMKKTKGLEKSQQILQSQLDDANEDIKNLNEE 291 Query: 564 LHHLSQKVAELEE-------EKGNLQLHLVDYDS----------GRMIESDV-YKKMIEM 605 L +QK +E+ E L+ L + D+ G + +SD +K+ + Sbjct: 292 LRLANQKTQSIEKSMRSLQRENSELKAKLDEKDAEHETTISEMKGEIAKSDSNIRKIASL 351 Query: 606 ENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADI---SQLQSDQVCSEIKSV 662 + E + I+ + + +EL + + ++ K+ + + L S++ E +V Sbjct: 352 NSKIEDYQEEITRINDELAQTHEELRTVTSENARLKTKVGEFERRASLLSERPSKEQFTV 411 Query: 663 HLEEQIDALSASKKELAL----VIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENM 718 LEE+ L + E L IE + + ++L TI +++N I + ++ QEN Sbjct: 412 -LEEENARLKSKINENQLKYQQSIETAQNENKELKQTISEIQNQTVQITKEKTSFEQENN 470 Query: 719 DLTDKL-EKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSR 777 DL E S ++ + L + N + K+QT + Q+ E ++++ K Sbjct: 471 DLKRIAGEVDSLKQQIKSLKQDNDILKDKLQTAEEKASNTQKAQSSFERLQNDYRNLKQE 530 Query: 778 ICRLEE----SIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDH 833 + E SI+ ++ L+ + L + KQ + + L N + L H Sbjct: 531 VNENTEKHKNSISQLKKENSQLKETIEDLEDQIHAKQNSLDREKSNNNNLRNTIEEL--H 588 Query: 834 DRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESES 893 + +E L L+KK EN++L+ S D Q + D +E+ Sbjct: 589 SKSLENSRL--------LEKKK----AENEDLKQSYEDAQSKSIISSSQQRSIDRLRNEN 636 Query: 894 TKYQTQLRDLESNLKRITHEHQTLIVQK-KKEIEDLEIEFNTQIESAIRDKKVLNEKYEK 952 + + + DL++ L + QT +QK K E E+L+ E ++ ++ + N + ++ Sbjct: 637 NELRETIEDLQNQLG--NNGSQTKTIQKLKAENEELKAEMESKQNRSLERLRNENRQLKQ 694 Query: 953 NI---EYVTQL-EAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYI 1008 I + QL ++QLQ L +E+L +++ + K + + + ++ D E+ Sbjct: 695 EIADLDSKYQLSQSQLQSTVKENAGLKQEIEDLEDQSMQNVSKEIDRLKNENLDLKEKID 754 Query: 1009 N-EINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRV 1067 + N+ +A LK ++E+ L Q I + + + +S+ + K ++ E Sbjct: 755 RLQNNRSSARLKAENED---LKQTIEELKSQMSKSIDNLKSENRELRRKNSDLVE----- 806 Query: 1068 SKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANN 1127 + Q+ + + ++ L RE D EL+ KL+ N + +I T + N Sbjct: 807 ATQIKPTDVDQDTIEQLTREND----ELRR-KLSLSKNDNEKSNLIEQVT----TLKEKN 857 Query: 1128 VDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTG 1187 ++ ++ ++ S LQ Q+A L +L E +I+ E + Sbjct: 858 IELLMKMRDMMEDAENGNNNDQMKRQVSDLQRQNADLQRQLSES-QRILDNER-QKKSVN 915 Query: 1188 HDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWK-QHLAQR 1246 D ++Q+ I +L S+ ++ E ++L ++++ I +R + K L Sbjct: 916 DDTIDQKTI-KLISENREMKLEIESLKRSISDYEKLIDFERQKRYDNSDDKSKISRLIDE 974 Query: 1247 EADFQKTEHELRVQLS---AFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQ-NKLQDK 1302 D + +L ++LS F + ++S+++ N+ + +Q S Q N ++ Sbjct: 975 NNDLRSVIKDLNLKLSEKKEFADSVRRRIESIEAKVGYVANEFSSYKQRKSSQYNGNENN 1034 Query: 1303 EEHLRNLQEKYADVINQIEILRSEI 1327 E +R LQ++ +++ + L+ EI Sbjct: 1035 SEEVRYLQKENQRLVSLVSKLKCEI 1059 Score = 92.7 bits (220), Expect = 8e-17 Identities = 186/922 (20%), Positives = 381/922 (41%), Gaps = 63/922 (6%) Query: 215 KQQMTKMQ-EN-FIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHS 272 K Q+ K+Q EN + + +D+ L + I+S + S E K L + EI + Sbjct: 129 KHQIKKLQRENSHLQDKLNERDKSGDLRRKIQSLKNDMDSKETEIKQLNSTLKEIKQKFE 188 Query: 273 KLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLE 332 K Q+ E+ ++++ S + KTE + ++ +++L ++ E L+ Sbjct: 189 KQKQDNEKLRNDYHEL--------QETVVTSVDTKTEEIRPDDIRMSQLSQLQRENEQLQ 240 Query: 333 HLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSE 392 H +I E + L + K K L S+ N K + +L+++ Sbjct: 241 H---KISILEDEAQKSLEISQEDMKKTKGLEKSQQILQSQLDDANEDIKNLNEELRLANQ 297 Query: 393 TLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQL 452 Q +K + + E+ + KD + E ISE IA L Sbjct: 298 K-TQSIEKSMRSLQRENSELKAKLDEKD-AEHETTISE----MKGEIAKSDSNIRKIASL 351 Query: 453 QLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQI 512 + + + E + + +E + L ++ + + + + ++EQ Sbjct: 352 NSKIEDYQE--EITRINDELAQTHEELRTVTSENARLKTKVGEFERRASLLSERPSKEQF 409 Query: 513 TQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSK-----VSDSNKEIVRLTEELHHL 567 T L +E +A K+ I + ++LK +Q +T N +K +S+ + V++T+E Sbjct: 410 TVLEEE-NARLKSKI---NENQLKYQQSIETAQNENKELKQTISEIQNQTVQITKEKTSF 465 Query: 568 SQKVAELEEEKGNLQLHLVDYDSGRMIESDVYK-KMIEMENLAETRLKAISLLESQKFDL 626 Q+ +L+ G + L ++D+ K K+ E A KA S E + D Sbjct: 466 EQENNDLKRIAGEVD-SLKQQIKSLKQDNDILKDKLQTAEEKASNTQKAQSSFERLQNDY 524 Query: 627 VQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSV--HLEEQIDALSASKKELALVIEN 684 ++ Q+ + E ISQL+ + S++K LE+QI A S N Sbjct: 525 ---RNLKQEVNENTEKHKNSISQLKKEN--SQLKETIEDLEDQIHAKQNSLDREKSNNNN 579 Query: 685 LKLDKEQLYGTIKDLENDKEDIMNKLQN--YIQENMDLTDK-LEKMSAEKISELLAKINH 741 L+ E+L+ K LEN + K +N Q D K + S ++ + L N+ Sbjct: 580 LRNTIEELHS--KSLENSRLLEKKKAENEDLKQSYEDAQSKSIISSSQQRSIDRLRNENN 637 Query: 742 EEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRI-CRLEESIAVMEDRRYSLERKAD 800 E + I+ + I+ +++E + K+ + + S+ + + L+++ Sbjct: 638 ELRETIEDLQNQLGNNGSQTKTIQKLKAENEELKAEMESKQNRSLERLRNENRQLKQEIA 697 Query: 801 QLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHD-RVVEKQLLEIEHENKELQKKNQILL 859 L S Q Q + L + L D + V K++ +++EN +L++K L Sbjct: 698 DLDSKYQLSQSQLQSTVKENAGLKQEIEDLEDQSMQNVSKEIDRLKNENLDLKEKIDRLQ 757 Query: 860 EENQN--LQISLSDMQQHYNALVEKANRT-DLAESESTKYQTQLRDL-ESNLKRITHEHQ 915 + L+ D++Q L + +++ D +SE+ + + + DL E+ + T Q Sbjct: 758 NNRSSARLKAENEDLKQTIEELKSQMSKSIDNLKSENRELRRKNSDLVEATQIKPTDVDQ 817 Query: 916 TLIVQKKKEIEDLEIEFNTQIESAIRDKKV--LNEKYEKNIEYVTQLEAQLQ--EYKNNI 971 I Q +E ++L + + + + + EKNIE + ++ ++ E NN Sbjct: 818 DTIEQLTRENDELRRKLSLSKNDNEKSNLIEQVTTLKEKNIELLMKMRDMMEDAENGNNN 877 Query: 972 ENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQK 1031 + + V +L + N +L Q+Q ++S + + + + + QK ++I+ N++ Sbjct: 878 DQMKRQVSDLQRQNADL-----QRQLSESQRILDNERQKKSVNDDTIDQKTIKLISENRE 932 Query: 1032 INNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQ 1091 + S +SDYE + K + ++ ++S+ L+D N +L+ ++++ + + Sbjct: 933 MKLEIESLKRSISDYEKLIDFERQKRYDNSDDKSKISR-LID---ENNDLRSVIKDLNLK 988 Query: 1092 IKELKETKLTFEMNIPKTEGMI 1113 + E KE + I E + Sbjct: 989 LSEKKEFADSVRRRIESIEAKV 1010 Score = 72.9 bits (171), Expect = 7e-11 Identities = 121/617 (19%), Positives = 270/617 (43%), Gaps = 58/617 (9%) Query: 212 EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271 E+ K Q +F ++ ++++ KQ + ++ E IS L++ N L+ ++ + Sbjct: 504 EEKASNTQKAQSSFERLQNDYRNLKQEVNENTEKHKNSISQLKKENSQLKETIEDLEDQI 563 Query: 272 SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSC---EEKTEIEE-KGSLEIANMTELT-- 325 L++ L +S+E S ++K E E+ K S E A + Sbjct: 564 HAKQNSLDREKSNNNNLRNTIEELHSKSLENSRLLEKKKAENEDLKQSYEDAQSKSIISS 623 Query: 326 ---KKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTAS-- 380 + I+ L + N ++R+T ++L+N+L G+++K + + L + + S Sbjct: 624 SQQRSIDRLRNENNELRETIEDLQNQLGNNGSQTKTIQKLKAENEELKAEMESKQNRSLE 683 Query: 381 KMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXX 440 ++++ QL E + D+ +++++++ L +++ D E ++ Sbjct: 684 RLRNENRQLKQEIADLDSKYQLSQSQLQSTVKENAGLKQEIEDLE----DQSMQNVSKEI 739 Query: 441 XXXGKDTLIAQLQLEHQQHMEGPSLIHV------GTNTEDVNEIAKVQEQLKQELNDEIK 494 + L + +++ Q+ + + T E ++++K + LK E N E++ Sbjct: 740 DRLKNENLDLKEKIDRLQNNRSSARLKAENEDLKQTIEELKSQMSKSIDNLKSE-NRELR 798 Query: 495 DVNVKDLIE--KLKSAE------EQITQLNDEIDAANKNMIKVKSNHKLKLKQM-----Q 541 N DL+E ++K + EQ+T+ NDE+ K + N K L + + Sbjct: 799 RKN-SDLVEATQIKPTDVDQDTIEQLTRENDEL--RRKLSLSKNDNEKSNLIEQVTTLKE 855 Query: 542 KTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKK 601 K I+ K+ D ++ + ++V++L+ + +LQ L +S R+++++ KK Sbjct: 856 KNIELLMKMRDMMEDAENGNNN-DQMKRQVSDLQRQNADLQRQL--SESQRILDNERQKK 912 Query: 602 MIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADIS-QLQSDQVCSEIK 660 + + + + +K IS E+++ L E+ L++ + E KL D Q + D + K Sbjct: 913 SVNDDTIDQKTIKLIS--ENREMKL--EIESLKRSISDYE-KLIDFERQKRYDNSDDKSK 967 Query: 661 SVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDL 720 L ++ + L + K+L L + K + + I+ +E + N+ +Y Q Sbjct: 968 ISRLIDENNDLRSVIKDLNLKLSEKKEFADSVRRRIESIEAKVGYVANEFSSYKQRKSSQ 1027 Query: 721 TDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRIC- 779 + E ++E++ L Q + Q + +K++ + I NI ++ K + Sbjct: 1028 YNGNEN-NSEEVRYL--------QKENQRLVSLVSKLKCEIIGIRNIAAQQISSKKSLSP 1078 Query: 780 -RLEESIAVMEDRRYSL 795 ++E I E+ RY++ Sbjct: 1079 EEIKEIIRAFEELRYAV 1095 >UniRef50_A0DR44 Cluster: Chromosome undetermined scaffold_6, whole genome shotgun sequence; n=3; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_6, whole genome shotgun sequence - Paramecium tetraurelia Length = 1947 Score = 127 bits (306), Expect = 3e-27 Identities = 217/1148 (18%), Positives = 479/1148 (41%), Gaps = 100/1148 (8%) Query: 483 EQLKQELN-DEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANK----NMIKVKS-NHKLK 536 ++LK+E+ E+K ++ + + + + +++ DE NK N++ ++ N+K K Sbjct: 504 QKLKKEVQLSEVKFIDQTKITHQFEKEVNEKSRIIDEYKKKNKELQENLVSAQTENNKYK 563 Query: 537 LKQMQ-KTID------NFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYD 589 ++ ++ K ++ N K + +E+ R+ +E L +K+AELE + D + Sbjct: 564 IQLLEVKALEGGSANGNGQKSNSYQREVERIQDENARLQKKIAELENQVLEQNSKSSDQN 623 Query: 590 SGRMIESDV----YKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLA 645 R ++ + K + L++ R I+ L+ Q L+ E + ++ + D+V + Sbjct: 624 ESRKLQIQITQLEQSKFLINAQLSQ-REATITQLQRQIQGLLDE-NNMKSEGDQVIQERR 681 Query: 646 DISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKED 705 ++LQ + + ++ + KE L+ + LK +I +++ + Sbjct: 682 KNAELQLQLSNYQTSEKVWKSKLSDIEHKLKEQTLINQELKTKVNSSNPSITITKDENDR 741 Query: 706 IMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIE 765 +++ + ++ L K + I EL K+N E Q D +++ + Sbjct: 742 NYERIREQLSLELEAKTSLTKQLFQSIDELTIKLNQERSKSQNLQIEYDQLLEQTNF--- 798 Query: 766 NIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVN 825 R S + + + +R D + +++ Q S+ Q+ +L + Sbjct: 799 --------------RQNRSQTIQQQNQQKDQRIQD-FQAQIEQLQLELSKAKSQQSQLAS 843 Query: 826 RLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANR 885 L ++ + E +++E+EH+ + + Q +E+ + + + ++ N L E+ Sbjct: 844 MHQNLQENFKAAEMKIVELEHQKRMYDRTIQEKVEQVTSHETKIKELNTQKNQLDEQLTE 903 Query: 886 TDLAES------ESTKYQTQLRDLE-SNLKRITHEHQTLIVQKKKEI----EDLEIEFNT 934 + +S ES ++Q + E NLK+ E + +I+ + ++I E E E N Sbjct: 904 SLKKQSEQRVLLESLQFQVGNKGKEYENLKKKIEEQELIILGQNEKIHKVKESNEAEQNE 963 Query: 935 QIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQ 994 + + + + Y K E + + Q+ + I NLN V L + L +K V+ Sbjct: 964 KSILGTEQENLKKQLYMKE-EQIRSRQEQINSLNDQIRNLNEKVSSLEQQR-TLQNKQVK 1021 Query: 995 KQQTQSPDYTEQYINEINKLNA---LLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLA 1051 + Q +Y+ E +K+++ L KQ+ E A K+ + Y + +S+ +L Sbjct: 1022 HLEDQINSREREYMTEHSKVSSERDLQKQRVIEAEAQILKLQQSDKKYKTEISNLNEELQ 1081 Query: 1052 QFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEG 1111 Q LE++ ++++ Q S++ N E + Q ++++L++ + I + + Sbjct: 1082 QQLLTLEHLNKQIKDYEIQQNQSRESNLENS---KVQSIRLEKLEQQNQNMNIKI-EAQS 1137 Query: 1112 MIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQEC 1171 I + + + KVQEEE R ++Q ++ + Sbjct: 1138 QEIKQYTAKIEEQLTTI---------TELKYKVQEEESL---RKAKEKQVNDKTQQIGQL 1185 Query: 1172 YTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQR 1231 ++I+++ + Q Q + LK K + +L S E +S+ S ++ Sbjct: 1186 ENQLIKIQEKYNQSNRSSQDIQNQYDDLKKKFDVELNNMQSLQSRSIEY-NSLQSRYMEQ 1244 Query: 1232 GFEIAELWKQHLAQREA--DFQKTEHELRVQLSAFESK------YEQLLDSVQSSTQEET 1283 G +++ L KQ L E +QK + EL+ +SK +E + + + +E Sbjct: 1245 GQKLSSLEKQLLDYNEISDQYQKQKKELQSLTDLLDSKLATIVSHETKIIDLTNQLKESN 1304 Query: 1284 NKI--VTMEQVTSLQNKLQDKE--EHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXX 1339 +++ V E +Q + QD + L+ ++ + D+ Q+ + I++++ A Sbjct: 1305 SQLQQVRKENHEIMQKRAQDMQAMAQLKQIEVENGDLKQQVYSHEATIQNQE-ALLSVLK 1363 Query: 1340 XXXXXXXXXXXDLRTENQSYKQMQEQSILNINEE-----NAQLKKSSXXXXXXXXXXXXR 1394 L+ + Q + + +++++E+ N Q K S R Sbjct: 1364 GNQLNLEQSQMKLKIDYQHLDEKYNEKLIDLDEKSKTLFNLQNKFDSLSFRAQQSEENLR 1423 Query: 1395 VNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYE 1454 + + + + ++L L++ +IY K + I L N + E +++Q+ +K+ + L E Sbjct: 1424 LVEDQRDDYQSRYELALQELDIY-KGKDKEINLMAAN-KIE-LQEQMHSVQKKNKVLERE 1480 Query: 1455 KESELAILRLKMHENANHYETMQ-KESEIERVK-LIEELNVKITESVS----LNKQVAEL 1508 + L+ K + T+Q KE +I ++ I +L +T S + L ++ E+ Sbjct: 1481 LQVSQNALQSKESDILQLQHTIQKKEQQITTLEGTIVKLKADLTNSKNSYEQLQLELTEM 1540 Query: 1509 NK---ALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTK 1565 N + E ++ ++ N+ +I L +I LQ+ R + K S A Sbjct: 1541 NSEQTSSGELFSQVKKLTNDNLNKNTQIDQLKLQINELQDKNRNLEKQYNKLRSDALVGN 1600 Query: 1566 QGRDEQLD 1573 QG E + Sbjct: 1601 QGNSESFE 1608 Score = 124 bits (299), Expect = 2e-26 Identities = 232/1176 (19%), Positives = 511/1176 (43%), Gaps = 86/1176 (7%) Query: 456 HQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKL---KSAEEQI 512 + Q GP L T + +Q LKQ ++++ N++ L + +E + Sbjct: 402 NSQLNNGPELNRKKTVQMKQKDQTNIQGDLKQVEDEDLVFSNLRRKTMHLLNQEEVDEDV 461 Query: 513 TQLNDEIDAANKNMI---KVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQ 569 L D I+ + +I +V + LK+ +MQ+ + + K+ V+L+E Sbjct: 462 AVLTDYINKLEEVLILKHRVVKDQNLKILEMQEKNEKIFEEIQKLKKEVQLSEVKFIDQT 521 Query: 570 KVAELEEEKGNLQLHLVD--YDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFD-L 626 K+ E++ N + ++D + ++ ++ E N + +L + LE + Sbjct: 522 KITHQFEKEVNEKSRIIDEYKKKNKELQENLVSAQTE-NNKYKIQLLEVKALEGGSANGN 580 Query: 627 VQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASK-KELALVIENL 685 Q+ + Q++ + ++D+ A +LQ + +E+++ LE+ + ++ ++L + I L Sbjct: 581 GQKSNSYQREVERIQDENA---RLQ--KKIAELENQVLEQNSKSSDQNESRKLQIQITQL 635 Query: 686 KLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAE--KISELLAKI-NHE 742 + K + + E + ++Q + EN ++ + +++ E K +EL ++ N++ Sbjct: 636 EQSKFLINAQLSQREATITQLQRQIQGLLDEN-NMKSEGDQVIQERRKNAELQLQLSNYQ 694 Query: 743 EQSKI--QTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKAD 800 K+ I+ K++E+ L + ++++++ I ++ DR Y ER + Sbjct: 695 TSEKVWKSKLSDIEHKLKEQTLINQELKTKVNSSNPSITITKDE----NDRNY--ERIRE 748 Query: 801 QLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLE 860 QL L+ K + DEL +L + ++ + ++ + Q ++Q + + Sbjct: 749 QLSLELEAKTSLTKQLFQSIDELTIKLNQERSKSQNLQIEYDQLLEQTNFRQNRSQTIQQ 808 Query: 861 ENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQ 920 +NQ + D Q L + ++ A+S+ ++ + ++L+ N K E + + ++ Sbjct: 809 QNQQKDQRIQDFQAQIEQLQLELSK---AKSQQSQLASMHQNLQENFK--AAEMKIVELE 863 Query: 921 KKKEIEDLEIEFNT-QIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVE 979 +K + D I+ Q+ S K LN + + E +T+ + E + +E+L V Sbjct: 864 HQKRMYDRTIQEKVEQVTSHETKIKELNTQKNQLDEQLTESLKKQSEQRVLLESLQFQVG 923 Query: 980 ELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSY 1039 K E + K +++Q+ E+ I+++ + N +Q ++ I+ Q+ N + Y Sbjct: 924 NKGK-EYENLKKKIEEQELIILGQNEK-IHKVKESNE-AEQNEKSILGTEQE-NLKKQLY 979 Query: 1040 M--SMVSDYESKLAQFTTKLENMEEEMQRVSKQ-LLDSKQ--HNEELQILVREQDDQIKE 1094 M + + ++ ++ N+ E++ + +Q L +KQ H E+ QI RE++ Sbjct: 980 MKEEQIRSRQEQINSLNDQIRNLNEKVSSLEQQRTLQNKQVKHLED-QINSREREYM--- 1035 Query: 1095 LKETKLTFEMNIPKTEGMIISSTIEPM--SDDANNVDXXXXXXXXXXXXLKVQEEEEFIQ 1152 + +K++ E ++ K + + I + SD + L ++ + I+ Sbjct: 1036 TEHSKVSSERDLQKQRVIEAEAQILKLQQSDKKYKTEISNLNEELQQQLLTLEHLNKQIK 1095 Query: 1153 ERSVLQEQSAKLNTELQECYT-KIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTEND 1211 + + Q QS + N E + + ++ +LE N + ++I Q +K+E+ T Sbjct: 1096 DYEIQQNQSRESNLENSKVQSIRLEKLEQQNQNMNIKIEAQSQEIKQYTAKIEEQLTTIT 1155 Query: 1212 NLLSTVAE---LRSSISSAVDQRGFEIAELWKQHLAQREADFQ--KTEHELRVQLSAFES 1266 L V E LR + V+ + +I +L Q + +E Q ++ +++ Q + Sbjct: 1156 ELKYKVQEEESLRKAKEKQVNDKTQQIGQLENQLIKIQEKYNQSNRSSQDIQNQYDDLKK 1215 Query: 1267 KYEQLLDSVQS--STQEETNKIVT--MEQ---VTSLQNKLQDKEEHLRNLQEKYADVINQ 1319 K++ L+++QS S E N + + MEQ ++SL+ +L D E Q++ ++ + Sbjct: 1216 KFDVELNNMQSLQSRSIEYNSLQSRYMEQGQKLSSLEKQLLDYNEISDQYQKQKKELQSL 1275 Query: 1320 IEILRSEIED--EKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQ------SILNIN 1371 ++L S++ +R EN Q + Q + I Sbjct: 1276 TDLLDSKLATIVSHETKIIDLTNQLKESNSQLQQVRKENHEIMQKRAQDMQAMAQLKQIE 1335 Query: 1372 EENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTH-QLELK--DSEIYQKTHEYTITLT 1428 EN LK+ ++ + L L Q++LK + +K +E I L Sbjct: 1336 VENGDLKQQVYSHEATIQNQEALLSVLKGNQLNLEQSQMKLKIDYQHLDEKYNEKLIDLD 1395 Query: 1429 QRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLI 1488 +++ N++ + R + + E L ++ + + + YE +E +I + K Sbjct: 1396 EKSKTLFNLQNKFDSLSFRAQ----QSEENLRLVEDQRDDYQSRYELALQELDIYKGK-D 1450 Query: 1489 EELNVKITESVSLNKQ---VAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQN 1545 +E+N+ + L +Q V + NK LE E+ + Q AL+++E +I+ L I + Sbjct: 1451 KEINLMAANKIELQEQMHSVQKKNKVLERELQVS---QNALQSKESDILQLQHTIQKKEQ 1507 Query: 1546 MVRASSSKIQKHVSFASDTKQGRDE-QLDNT-MNKE 1579 + I K + +++K ++ QL+ T MN E Sbjct: 1508 QITTLEGTIVKLKADLTNSKNSYEQLQLELTEMNSE 1543 Score = 116 bits (280), Expect = 4e-24 Identities = 235/1231 (19%), Positives = 534/1231 (43%), Gaps = 85/1231 (6%) Query: 154 KDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXED 213 KD L +L+++ K I + +K+ ++ Q+ E K T ++ Sbjct: 483 KDQNLKILEMQEK--NEKIFEEIQKLKKEVQLSEVKFIDQTKITHQFEKEVNEKSRIIDE 540 Query: 214 TKQQMTKMQENFIAMEAEWKDEKQRLL--KDIESKDVRISSLEEANKLLEAARFEI-SLE 270 K++ ++QEN ++ + E K +LL K +E + + + E R + + Sbjct: 541 YKKKNKELQENLVSAQTENNKYKIQLLEVKALEGGSANGNGQKSNSYQREVERIQDENAR 600 Query: 271 HSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTE--IEEKGSLEIANMTELTKKI 328 K ELE K I+ + E+++ I + S A +T+L ++I Sbjct: 601 LQKKIAELENQVLEQNSKSSDQNESRKLQIQITQLEQSKFLINAQLSQREATITQLQRQI 660 Query: 329 E-LLEHLNC--------QIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTA 379 + LL+ N Q R+ N EL+ +L+ T K S + ++ N Sbjct: 661 QGLLDENNMKSEGDQVIQERRKNAELQLQLSNYQTSEKVWKSKLSDIEHKLKEQTLINQE 720 Query: 380 SKMKSPWSQLSSETLNQDTDKKINK-NEIAKLEMVIQ-SLNKDLVDKEYVISEK-DTXXX 436 K K S S + D+ + E LE+ + SL K L ++ K + Sbjct: 721 LKTKVNSSNPSITITKDENDRNYERIREQLSLELEAKTSLTKQLFQSIDELTIKLNQERS 780 Query: 437 XXXXXXXGKDTLIAQLQL-EHQQHMEGPSLIHVGTNTEDVN-EIAKVQEQLKQELNDEIK 494 D L+ Q +++ +D +I ++Q +L + + + + Sbjct: 781 KSQNLQIEYDQLLEQTNFRQNRSQTIQQQNQQKDQRIQDFQAQIEQLQLELSKAKSQQSQ 840 Query: 495 DVNV-KDLIEKLKSAEEQITQLNDE---IDAANKNMIKVKSNHKLKLKQMQKTIDNFSK- 549 ++ ++L E K+AE +I +L + D + ++ ++H+ K+K++ + + Sbjct: 841 LASMHQNLQENFKAAEMKIVELEHQKRMYDRTIQEKVEQVTSHETKIKELNTQKNQLDEQ 900 Query: 550 VSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLA 609 +++S K+ L L +V +E NL+ + + + + +++ K+ E N A Sbjct: 901 LTESLKKQSEQRVLLESLQFQVGNKGKEYENLKKKIEEQELIILGQNEKIHKVKE-SNEA 959 Query: 610 ETRLKAI-----SLLESQKFDLVQELHILQQKYDEVEDKLAD----ISQLQSDQVCSEIK 660 E K+I L+ Q + +++ Q++ + + D++ + +S L+ + + Sbjct: 960 EQNEKSILGTEQENLKKQLYMKEEQIRSRQEQINSLNDQIRNLNEKVSSLEQQRTLQNKQ 1019 Query: 661 SVHLEEQIDALSAS-KKELALVIENLKLDKEQLYGT----IKDLENDKE---DIMNKLQN 712 HLE+QI++ E + V L K+++ +K ++DK+ +I N + Sbjct: 1020 VKHLEDQINSREREYMTEHSKVSSERDLQKQRVIEAEAQILKLQQSDKKYKTEISNLNEE 1079 Query: 713 YIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELS 772 Q+ + L +++ +I + ++ ++ E SK+Q+ + Q +++ I+ IE++ Sbjct: 1080 LQQQLLTLEHLNKQIKDYEIQQNQSRESNLENSKVQSIRLEKLEQQNQNMNIK-IEAQSQ 1138 Query: 773 KYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMD 832 + K ++EE + + + +Y ++ + S + K+K ++ T Q +L N+L + + Sbjct: 1139 EIKQYTAKIEEQLTTITELKYKVQEEE----SLRKAKEKQVNDKTQQIGQLENQLIKIQE 1194 Query: 833 HDRVVEKQLLEIEHENKELQKKNQILLEENQNLQ---ISLSDMQQHYNALVEKANRTD-- 887 + +I+++ +L+KK + L Q+LQ I + +Q Y +K + + Sbjct: 1195 KYNQSNRSSQDIQNQYDDLKKKFDVELNNMQSLQSRSIEYNSLQSRYMEQGQKLSSLEKQ 1254 Query: 888 -LAESE-STKYQTQLRDLESNLKRITHEHQTLIVQKKKEIE--DLEIEFNTQIESAIRDK 943 L +E S +YQ Q ++L+S + + T++ + K I+ + E N+Q++ ++ Sbjct: 1255 LLDYNEISDQYQKQKKELQSLTDLLDSKLATIVSHETKIIDLTNQLKESNSQLQQVRKEN 1314 Query: 944 KVLNEKYEKNIEYVTQL---EAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQS 1000 + +K ++++ + QL E + + K + + ++ + L + +Q+Q Sbjct: 1315 HEIMQKRAQDMQAMAQLKQIEVENGDLKQQVYSHEATIQNQEALLSVLKGNQLNLEQSQM 1374 Query: 1001 P---DYTEQYINE-INKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTK 1056 DY Q+++E N+ L +K + + L K ++ +S+ + S+ +L + + Sbjct: 1375 KLKIDY--QHLDEKYNEKLIDLDEKSKTLFNLQNKFDS--LSFRAQQSEENLRLVE--DQ 1428 Query: 1057 LENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISS 1116 ++ + + ++L K ++E+ ++ + + +++ + + + + E + + Sbjct: 1429 RDDYQSRYELALQELDIYKGKDKEINLMAANKIELQEQMHSVQK--KNKVLERELQVSQN 1486 Query: 1117 TIEPMSDDANNVDXXXXXXXXXXXXLK---VQEEEEFIQERSVLQEQSAKLNTELQECYT 1173 ++ D + L+ V+ + + ++ ++ +L TE+ T Sbjct: 1487 ALQSKESDILQLQHTIQKKEQQITTLEGTIVKLKADLTNSKNSYEQLQLEL-TEMNSEQT 1545 Query: 1174 KIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGF 1233 +L + +LT ++ QI+QLK ++ +L +N NL +LRS + +Q Sbjct: 1546 SSGELFSQVKKLTNDNLNKNTQIDQLKLQINELQDKNRNLEKQYNKLRSD-ALVGNQGNS 1604 Query: 1234 EIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLD--SVQS--STQEETNKIVTM 1289 E EL + + + E F+++++ +R Q + +QLLD S QS S Q E + Sbjct: 1605 ESFEL-RSRVDELEGQFKQSQNSIR-QKDQQIQELKQLLDNQSYQSNQSNQREKEREREK 1662 Query: 1290 EQVTSLQNK-LQDKEEHLRNLQEKYADVINQ 1319 E+ NK + + +H ++Y +I Q Sbjct: 1663 EKEKQTYNKPINNSNDHENMKIQEYQFIIEQ 1693 Score = 110 bits (265), Expect = 3e-22 Identities = 223/1221 (18%), Positives = 523/1221 (42%), Gaps = 110/1221 (9%) Query: 305 EEKTEIEEKGSLEIANMT-ELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPS 363 +++ ++ E ++ +T + K++ + + ++ NKEL+ L + TE+ Sbjct: 507 KKEVQLSEVKFIDQTKITHQFEKEVNEKSRIIDEYKKKNKELQENLVSAQTENNKYKIQL 566 Query: 364 KKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVD 423 + L + G + KS Q E + QD + ++ K +IA+LE + N D Sbjct: 567 LEVKAL---EGGSANGNGQKSNSYQREVERI-QDENARLQK-KIAELENQVLEQNSKSSD 621 Query: 424 K------EYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNT-EDVN 476 + + I++ + ++ I QLQ + Q ++ ++ G ++ Sbjct: 622 QNESRKLQIQITQLEQSKFLINAQLSQREATITQLQRQIQGLLDENNMKSEGDQVIQERR 681 Query: 477 EIAKVQEQLKQ-ELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKL 535 + A++Q QL + ++++ + D+ KLK +L +++++N ++ K + Sbjct: 682 KNAELQLQLSNYQTSEKVWKSKLSDIEHKLKEQTLINQELKTKVNSSNPSITITKDENDR 741 Query: 536 KLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLH---LVDYDSGR 592 +++++ + + S + +L + + L+ K+ + + NLQ+ L++ + R Sbjct: 742 NYERIREQLSLELEAKTSLTK--QLFQSIDELTIKLNQERSKSQNLQIEYDQLLEQTNFR 799 Query: 593 MIESDVYKKMIEMENLAETRLKA--------ISLLESQKFDLVQELHILQQKYDEVEDKL 644 S ++ + ++ +A +S +SQ+ L LQ+ + E K+ Sbjct: 800 QNRSQTIQQQNQQKDQRIQDFQAQIEQLQLELSKAKSQQSQLASMHQNLQENFKAAEMKI 859 Query: 645 ADISQLQS--DQVCSE-IKSVHLEE-QIDALSASKKEL-ALVIENLKLDKEQ--LYGTIK 697 ++ + D+ E ++ V E +I L+ K +L + E+LK EQ L +++ Sbjct: 860 VELEHQKRMYDRTIQEKVEQVTSHETKIKELNTQKNQLDEQLTESLKKQSEQRVLLESLQ 919 Query: 698 DLENDKEDIMNKLQNYIQEN----MDLTDKLEKMSAEKISELLAK-INHEEQSKIQTQFG 752 +K L+ I+E + +K+ K+ +E K I EQ ++ Q Sbjct: 920 FQVGNKGKEYENLKKKIEEQELIILGQNEKIHKVKESNEAEQNEKSILGTEQENLKKQLY 979 Query: 753 I-DAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGS----YLQ 807 + + +I+ R I ++ ++ ++ LE+ + + LE DQ+ S Y+ Sbjct: 980 MKEEQIRSRQEQINSLNDQIRNLNEKVSSLEQQRTLQNKQVKHLE---DQINSREREYMT 1036 Query: 808 EKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQI 867 E K SE +Q+ ++ A ++ + +K EI + N+ELQ+ Q+L E+ N QI Sbjct: 1037 EHSKVSSERDLQKQRVIEAEAQILKLQQSDKKYKTEISNLNEELQQ--QLLTLEHLNKQI 1094 Query: 868 SLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIED 927 ++QQ+ + N + + K + Q +++ ++ + E + + ++++ Sbjct: 1095 KDYEIQQNQSRESNLEN-SKVQSIRLEKLEQQNQNMNIKIEAQSQEIKQYTAKIEEQLTT 1153 Query: 928 L-EIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNL 986 + E+++ Q E ++R K ++ + + QLE QL + + N + +++ Sbjct: 1154 ITELKYKVQEEESLRKAK--EKQVNDKTQQIGQLENQLIKIQEKYNQSNRSSQDIQNQYD 1211 Query: 987 ELIDK------HVQKQQTQSPDYTE---QYINEINKLNALLKQKDE--EIIALNQK---- 1031 +L K ++Q Q++S +Y +Y+ + KL++L KQ + EI QK Sbjct: 1212 DLKKKFDVELNNMQSLQSRSIEYNSLQSRYMEQGQKLSSLEKQLLDYNEISDQYQKQKKE 1271 Query: 1032 ---INNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHN-EELQILVRE 1087 + + S ++ + +E+K+ T +L+ ++Q+V K+ + Q +++Q + + Sbjct: 1272 LQSLTDLLDSKLATIVSHETKIIDLTNQLKESNSQLQQVRKENHEIMQKRAQDMQAMAQL 1331 Query: 1088 QDDQIK--ELKETKLTFEMNIPKTEGMI---------ISSTIEPMSDDANNVDXXXXXXX 1136 + +++ +LK+ + E I E ++ + + + D ++D Sbjct: 1332 KQIEVENGDLKQQVYSHEATIQNQEALLSVLKGNQLNLEQSQMKLKIDYQHLDEKYNEKL 1391 Query: 1137 X-----XXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTEL-TGHDV 1190 +Q + + + R+ E++ +L + ++ Y +L ++ G D Sbjct: 1392 IDLDEKSKTLFNLQNKFDSLSFRAQQSEENLRLVEDQRDDYQSRYELALQELDIYKGKDK 1451 Query: 1191 -VNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREAD 1249 +N N+++ + EQ+++ EL+ S +A+ + +I +L QH Q++ Sbjct: 1452 EINLMAANKIELQ-EQMHSVQKKNKVLERELQVS-QNALQSKESDILQL--QHTIQKKEQ 1507 Query: 1250 ----FQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEH 1305 + T +L+ L+ ++ YEQL + E+T+ QV L N +K Sbjct: 1508 QITTLEGTIVKLKADLTNSKNSYEQLQLELTEMNSEQTSSGELFSQVKKLTNDNLNKNTQ 1567 Query: 1306 LRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQ 1365 + L+ + IN+++ +E + +LR+ + +Q Sbjct: 1568 IDQLKLQ----INELQDKNRNLEKQYNKLRSDALVGNQGNSESF-ELRSRVDELEGQFKQ 1622 Query: 1366 SILNINEENAQLKK-----SSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQ-- 1418 S +I +++ Q+++ + + + E + + T+ + +S ++ Sbjct: 1623 SQNSIRQKDQQIQELKQLLDNQSYQSNQSNQREKEREREKEKEKQTYNKPINNSNDHENM 1682 Query: 1419 KTHEYTITLTQRNDEFENVRQ 1439 K EY + Q+ +E EN+++ Sbjct: 1683 KIQEYQFIIEQQTEEIENMKR 1703 Score = 101 bits (242), Expect = 2e-19 Identities = 178/948 (18%), Positives = 398/948 (41%), Gaps = 86/948 (9%) Query: 606 ENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLE 665 +N+A+ + +++ E ++ + + Q KY ++D + +S Q +K++ + Sbjct: 311 QNIADVKANQLNIEE------IEVILLRQVKYSMIQD---GYFKTKSVQFSPYVKTMSIS 361 Query: 666 EQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLE 725 + S+ ++ N+ D+ + I +EN KE+I KL + + +L K Sbjct: 362 QITSRFSSVIQDTTS--SNMDFDRVSILNKI--VENQKEEIA-KLNSQLNNGPELNRKKT 416 Query: 726 KMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYI---ENIESELSKYKSRICRLE 782 +K + + +++ + + + ++ + +++ E ++ +++ I +LE Sbjct: 417 VQMKQKDQTNI----QGDLKQVEDEDLVFSNLRRKTMHLLNQEEVDEDVAVLTDYINKLE 472 Query: 783 ESIA----VMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVV- 837 E + V++D+ + ++ +E QK E + E + +++ + ++ V Sbjct: 473 EVLILKHRVVKDQNLKILEMQEKNEKIFEEIQKLKKEVQLSEVKFIDQTKITHQFEKEVN 532 Query: 838 EKQLL--EIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVE-KANRTDLAESEST 894 EK + E + +NKELQ+ EN +I L +++ +++ + E Sbjct: 533 EKSRIIDEYKKKNKELQENLVSAQTENNKYKIQLLEVKALEGGSANGNGQKSNSYQREVE 592 Query: 895 KYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNI 954 + Q + L+ + + E+Q L K ++ + QI + K ++N + + Sbjct: 593 RIQDENARLQKKIAEL--ENQVLEQNSKSSDQNESRKLQIQITQLEQSKFLINAQLSQRE 650 Query: 955 EYVTQLEAQLQEY--KNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEIN 1012 +TQL+ Q+Q +NN+++ V + + N EL Q Q + + + ++++ Sbjct: 651 ATITQLQRQIQGLLDENNMKSEGDQVIQERRKNAEL-----QLQLSNYQTSEKVWKSKLS 705 Query: 1013 KLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLL 1072 + LK++ L K+N++ S + + + +L E ++KQL Sbjct: 706 DIEHKLKEQTLINQELKTKVNSSNPSITITKDENDRNYERIREQLSLELEAKTSLTKQLF 765 Query: 1073 DSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXX 1132 S +EL I + ++ + + L+ + ++ + +T + + + D Sbjct: 766 QSI---DELTIKLNQERSKSQNLQ---IEYDQLLEQTN--FRQNRSQTIQQQNQQKDQRI 817 Query: 1133 XXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVN 1192 L+++ + Q+ S L L + KI++LE Sbjct: 818 QDFQAQIEQLQLELSKAKSQQ-SQLASMHQNLQENFKAAEMKIVELEHQKRMYDRTIQEK 876 Query: 1193 QEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQK 1252 EQ+ ++K+++LNT+ + L + E S+ +QR + E + + + +++ Sbjct: 877 VEQVTSHETKIKELNTQKNQLDEQLTE---SLKKQSEQR--VLLESLQFQVGNKGKEYEN 931 Query: 1253 TEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEK 1312 + ++ Q + E++ +S+ E+ K + + +L+ +L KEE +R+ QE+ Sbjct: 932 LKKKIEEQELIILGQNEKIHKVKESNEAEQNEKSILGTEQENLKKQLYMKEEQIRSRQEQ 991 Query: 1313 YADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRT-ENQSYKQMQEQSILNIN 1371 + +QI L +EKV+ RT +N+ K +++Q IN Sbjct: 992 INSLNDQIRNL-----NEKVS--------------SLEQQRTLQNKQVKHLEDQ----IN 1028 Query: 1372 EENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRN 1431 + RV +AEA++L+L + +EI E L Q+ Sbjct: 1029 SREREYMTEHSKVSSERDLQKQRVIEAEAQILKLQQSDKKYKTEISNLNEE----LQQQL 1084 Query: 1432 DEFENVRQQLVEYEKRIEDLTYE--KESELAILRLKMHENANHYETMQKESEIERVKL-- 1487 E++ +Q+ +YE + + S++ +RL+ E N ++ E++ + +K Sbjct: 1085 LTLEHLNKQIKDYEIQQNQSRESNLENSKVQSIRLEKLEQQNQNMNIKIEAQSQEIKQYT 1144 Query: 1488 --IEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEI 1533 IEE ITE ++ L KA E++V + LENQ I+I Sbjct: 1145 AKIEEQLTTITELKYKVQEEESLRKAKEKQVNDKTQQIGQLENQLIKI 1192 Score = 95.1 bits (226), Expect = 1e-17 Identities = 187/997 (18%), Positives = 408/997 (40%), Gaps = 76/997 (7%) Query: 235 EKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXX 294 E++ L K + K+ +I S +E L ++ + S L Q+ Sbjct: 970 EQENLKKQLYMKEEQIRSRQEQINSLNDQIRNLNEKVSSLEQQRTLQNKQVKHLEDQINS 1029 Query: 295 LAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGT 354 ++ + + +E + + I ++ K + + +I N+EL+ +L T+ Sbjct: 1030 REREYMTEHSKVSSERDLQKQRVIEAEAQILKLQQSDKKYKTEISNLNEELQQQLLTLEH 1089 Query: 355 ESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVI 414 +K + + + SR+S + +L + N + + EI + I Sbjct: 1090 LNKQIKDYEIQQNQ--SRESNLENSKVQSIRLEKLEQQNQNMNIKIEAQSQEIKQYTAKI 1147 Query: 415 QSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQ-----LEHQQHMEGPSLIHVG 469 + + + +Y + E+++ K I QL+ ++ + + S + Sbjct: 1148 EEQLTTITELKYKVQEEESLRKAKEKQVNDKTQQIGQLENQLIKIQEKYNQSNRSSQDIQ 1207 Query: 470 TNTEDVNEIAKVQEQLKQELNDEIKDVN-----VKDLIEKLKSAEEQITQLNDEIDAANK 524 +D+ + V+ Q L + N + +KL S E+Q+ N+ D K Sbjct: 1208 NQYDDLKKKFDVELNNMQSLQSRSIEYNSLQSRYMEQGQKLSSLEKQLLDYNEISDQYQK 1267 Query: 525 NMIKVKS-----NHKLK--LKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEE 577 +++S + KL + K ID +++ +SN ++ ++ +E H + QK A ++ Sbjct: 1268 QKKELQSLTDLLDSKLATIVSHETKIIDLTNQLKESNSQLQQVRKENHEIMQKRA--QDM 1325 Query: 578 KGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKY 637 + QL ++ ++G D+ +++ E + + +S+L+ + +L Q L+ Y Sbjct: 1326 QAMAQLKQIEVENG-----DLKQQVYSHEATIQNQEALLSVLKGNQLNLEQSQMKLKIDY 1380 Query: 638 DEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIK 697 +++K + + D+ + +L+ + D+LS ++ ENL+L ++Q Sbjct: 1381 QHLDEKYNE-KLIDLDEKSKTL--FNLQNKFDSLSFRAQQSE---ENLRLVEDQR----D 1430 Query: 698 DLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKI 757 D ++ E + +L Y ++ + + M+A KI L + H Q K + ++ ++ Sbjct: 1431 DYQSRYELALQELDIYKGKDKE----INLMAANKIE--LQEQMHSVQKKNKV---LEREL 1481 Query: 758 QERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERK-ADQLGSYLQ---EKQKAY 813 Q +++ ES++ + + I + E+ I +E L+ + SY Q E + Sbjct: 1482 QVSQNALQSKESDILQLQHTIQKKEQQITTLEGTIVKLKADLTNSKNSYEQLQLELTEMN 1541 Query: 814 SEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQ 873 SE T EL +++ L + + Q+ +++ + ELQ KN+ L ++ L+ Sbjct: 1542 SEQT-SSGELFSQVKKLTNDNLNKNTQIDQLKLQINELQDKNRNLEKQYNKLRSDALVGN 1600 Query: 874 QHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIE-DLEIEF 932 Q + E +R D E + + Q +R + ++ + Q + + + E E Sbjct: 1601 QGNSESFELRSRVDELEGQFKQSQNSIRQKDQQIQELKQLLDNQSYQSNQSNQREKERER 1660 Query: 933 NTQIESAIRDKKVLNEKYEKNI---EYVTQLEAQLQEYKN---NIENLNMNVEELNKMNL 986 + E +K + N +N+ EY +E Q +E +N N + L + EL + + Sbjct: 1661 EKEKEKQTYNKPINNSNDHENMKIQEYQFIIEQQTEEIENMKRNSQGLGEELTELLTLVV 1720 Query: 987 EL-IDKHVQKQQTQSPDYTEQ--YINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMV 1043 + + K ++K Q +Q + NK + ++ DE+++ QK+ + Y++ Sbjct: 1721 NVFLKKKIKKDQLNIATVLDQIKLFQKENKTLTIREEDDEQLVL--QKLQQYRGDYINFR 1778 Query: 1044 SDYESKLAQFTT----KLENMEEEMQRVSKQLLDSKQHNEEL----QILVREQ------D 1089 E L + T L+ + E + K+ +D E L ++L+ Q Sbjct: 1779 FRVEQNLTRITVLKQQMLQIISEAKIQGKKKDVDKNMDVENLVMYFKLLLDSQAVQYSNQ 1838 Query: 1090 DQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEE 1149 Q+ + E +L N +G II E +S +K++++++ Sbjct: 1839 LQLCQQYEAELRSYQNNTSPQGQIIQQVKELLSKAPFLTQQQIYQFTEPKVSIKLRKDQD 1898 Query: 1150 FIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELT 1186 R +L+ ++ ++ K QL +NT LT Sbjct: 1899 QEDARLLLEARNQQIQWLKNLINEKQDQLAVMNTYLT 1935 Score = 79.0 bits (186), Expect = 1e-12 Identities = 165/879 (18%), Positives = 354/879 (40%), Gaps = 89/879 (10%) Query: 732 ISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDR 791 IS++ ++ + Q + D ++ + +EN + E++K S+ L + + Sbjct: 360 ISQITSRFSSVIQDTTSSNMDFD-RVSILNKIVENQKEEIAKLNSQ---LNNGPELNRKK 415 Query: 792 RYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENK-- 849 +++K DQ +Q K + + L + L++ + V E + ++ NK Sbjct: 416 TVQMKQK-DQTN--IQGDLKQVEDEDLVFSNLRRKTMHLLNQEEVDEDVAVLTDYINKLE 472 Query: 850 -ELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLES-NL 907 L K++++ ++QNL+I +MQ+ + E E + K + QL +++ + Sbjct: 473 EVLILKHRVV--KDQNLKIL--EMQEKNEKIFE--------EIQKLKKEVQLSEVKFIDQ 520 Query: 908 KRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEA----- 962 +ITH+ + + +K + I++ + + N +++ + + N KY+ + V LE Sbjct: 521 TKITHQFEKEVNEKSRIIDEYKKK-NKELQENLVSAQTENNKYKIQLLEVKALEGGSANG 579 Query: 963 ---QLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLK 1019 + Y+ +E + L K EL + V +Q ++S D NE KL + Sbjct: 580 NGQKSNSYQREVERIQDENARLQKKIAEL-ENQVLEQNSKSSDQ-----NESRKLQIQIT 633 Query: 1020 QKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLEN---MEEEMQRVSKQLLDSKQ 1076 Q ++ +N +++ + + + + L + K E ++E + QL S Sbjct: 634 QLEQSKFLINAQLSQREATITQLQRQIQGLLDENNMKSEGDQVIQERRKNAELQLQLSNY 693 Query: 1077 HNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXX 1136 E ++ + D +LKE L + K S TI +D N Sbjct: 694 QTSE-KVWKSKLSDIEHKLKEQTLINQELKTKVNSSNPSITITKDENDRNYERIREQLSL 752 Query: 1137 XXXXXLKVQEEE-EFIQERSVLQEQSAKLNTELQECYTKIIQL----ETLNTELTGHDVV 1191 + ++ + I E ++ Q + LQ Y ++++ + + + + Sbjct: 753 ELEAKTSLTKQLFQSIDELTIKLNQERSKSQNLQIEYDQLLEQTNFRQNRSQTIQQQNQQ 812 Query: 1192 NQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQ 1251 ++I ++++EQL E S ++L S + Q F+ AE+ L ++ + Sbjct: 813 KDQRIQDFQAQIEQLQLELSKAKSQQSQLASMHQNL--QENFKAAEMKIVELEHQKRMYD 870 Query: 1252 KTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQE 1311 +T E Q+++ E+K ++L T K EQ+T K ++ L +LQ Sbjct: 871 RTIQEKVEQVTSHETKIKEL----------NTQKNQLDEQLTESLKKQSEQRVLLESLQF 920 Query: 1312 KYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNIN 1371 + + + E L+ +IE++++ + + + + E+SIL Sbjct: 921 QVGNKGKEYENLKKKIEEQELIILGQNEKIH----------KVKESNEAEQNEKSILGTE 970 Query: 1372 EENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRN 1431 +EN LKK ++N ++ L ++ + + + + Q N Sbjct: 971 QEN--LKKQLYMKEEQIRSRQEQINSLNDQIRNLNEKVSSLEQQRTLQNKQVKHLEDQIN 1028 Query: 1432 DEFENVRQQLVEYEK--RIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIE 1489 R+ + E+ K DL ++ E LK+ ++ Y+T E L E Sbjct: 1029 ---SREREYMTEHSKVSSERDLQKQRVIEAEAQILKLQQSDKKYKT-------EISNLNE 1078 Query: 1490 ELNVKITESVSLNKQVAEL----NKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQN 1545 EL ++ LNKQ+ + N++ E + + LE E + +N +I Sbjct: 1079 ELQQQLLTLEHLNKQIKDYEIQQNQSRESNLENSKVQSIRLEKLEQQNQNMNIKIEAQSQ 1138 Query: 1546 MVRASSSKIQKHVSFASDTKQ--GRDEQLDNTMNKELLD 1582 ++ ++KI++ ++ ++ K +E L K++ D Sbjct: 1139 EIKQYTAKIEEQLTTITELKYKVQEEESLRKAKEKQVND 1177 Score = 65.7 bits (153), Expect = 1e-08 Identities = 109/607 (17%), Positives = 254/607 (41%), Gaps = 46/607 (7%) Query: 956 YVTQLEAQLQEYKNNIENLNMNVEEL--NKMNLELIDKHVQKQQTQSPDYTEQYINEINK 1013 Y +AQ + K L+ N+ ++ N++N+E I+ + +Q S + + + Sbjct: 291 YSLHQQAQDEFIKFIASALSQNIADVKANQLNIEEIEVILLRQVKYSMIQDGYFKTKSVQ 350 Query: 1014 LNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLD 1073 + +K I + + ++ S D++ +++ +EN +EE+ +++ QL + Sbjct: 351 FSPYVKTMS--ISQITSRFSSVIQDTTSSNMDFD-RVSILNKIVENQKEEIAKLNSQLNN 407 Query: 1074 SKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXX 1133 + N R++ Q+K+ +T + ++ + E ++ S+ N + Sbjct: 408 GPELN-------RKKTVQMKQKDQTNIQGDLKQVEDEDLVFSNLRRKTMHLLNQEEVDED 460 Query: 1134 XXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQ-LETLNTELTGHDV-- 1190 K+ EE I + V+++Q+ K+ E+QE KI + ++ L E+ +V Sbjct: 461 VAVLTDYINKL--EEVLILKHRVVKDQNLKI-LEMQEKNEKIFEEIQKLKKEVQLSEVKF 517 Query: 1191 VNQEQI-NQLKSKLEQLNTENDNLLSTVAELRSSISSA-VDQRGFEIAELWKQHLAQREA 1248 ++Q +I +Q + ++ + + D EL+ ++ SA + ++I L + L A Sbjct: 518 IDQTKITHQFEKEVNEKSRIIDEYKKKNKELQENLVSAQTENNKYKIQLLEVKALEGGSA 577 Query: 1249 DFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRN 1308 + + + Y++ ++ +Q KI +E QN + R Sbjct: 578 NGNGQK----------SNSYQREVERIQDENARLQKKIAELENQVLEQNSKSSDQNESRK 627 Query: 1309 LQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSIL 1368 LQ + + ++ +++ + L EN + + ++ Sbjct: 628 LQIQITQLEQSKFLINAQLSQREATITQLQRQIQG--------LLDENNM--KSEGDQVI 677 Query: 1369 NINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLT 1428 +NA+L+ +++D E K+ E T + +++ TIT Sbjct: 678 QERRKNAELQLQLSNYQTSEKVWKSKLSDIEHKLKEQTLINQELKTKVNSSNPSITITKD 737 Query: 1429 QRNDEFENVRQQL-VEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKL 1487 + + +E +R+QL +E E + LT + + L +K+++ + + +Q IE +L Sbjct: 738 ENDRNYERIREQLSLELEAK-TSLTKQLFQSIDELTIKLNQERSKSQNLQ----IEYDQL 792 Query: 1488 IEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMV 1547 +E+ N + S ++ +Q + ++ +++ A+ ++Q L + + L NLQ Sbjct: 793 LEQTNFRQNRSQTIQQQNQQKDQRIQDFQAQIEQLQLELSKAKSQQSQLASMHQNLQENF 852 Query: 1548 RASSSKI 1554 +A+ KI Sbjct: 853 KAAEMKI 859 >UniRef50_UPI00006CB6DE Cluster: hypothetical protein TTHERM_00494050; n=1; Tetrahymena thermophila SB210|Rep: hypothetical protein TTHERM_00494050 - Tetrahymena thermophila SB210 Length = 1181 Score = 126 bits (305), Expect = 4e-27 Identities = 227/1129 (20%), Positives = 489/1129 (43%), Gaps = 96/1129 (8%) Query: 476 NEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDE---IDAANKNMIK---- 528 + + + ++LK + + ++ +EK++ E ++ QL E ID + ++ Sbjct: 45 SSLFNMSQELKYSTPSILNNQEKEEKLEKIRQMESRMKQLQQEKMQIDLSVSETVERTQL 104 Query: 529 VKSNHKLK--LKQMQKTIDNFSKVSDSNKEIVRLTEELH---HLSQKVAELEEEKGNL-- 581 V+ N+ LK L M+ I + + + V L+ E KV +L +E NL Sbjct: 105 VQENNDLKNQLYAMELQIKQYQQHQQQDLTEVSLSLEKQKQIEFENKVNQLVKENANLIE 164 Query: 582 QLHLVDYDSGRMIESD----VYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKY 637 Q ++ D +I+ + +++E + LA R+ LE + L E+ +Q Sbjct: 165 QFNMAKQDLELLIKQKEVDRAHIQVLEEKLLAFERMN--EKLEEKNIQLRDEMIKIQYHS 222 Query: 638 DEVEDKLADIS---QLQSDQVCSEIKSVHLEE----QIDALSASKKELALVIENLKLDKE 690 + E+ + D+ + +D + E+K+ + E Q S K+L L +L+ + E Sbjct: 223 NTDENYVQDLKNQYKRVNDLLDLELKNKKVYEMQLIQAKQSQQSLKQLELEYTSLQQNLE 282 Query: 691 QLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQ 750 +L ++L + I Q Y EN LEK S KI +L +++ +Q+ Q Sbjct: 283 KLKKLNQELTIENNTIK---QQYYSENQK-NIILEKNSL-KIYQLQKELDISQQNTQDIQ 337 Query: 751 FGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQ 810 + A+ Q++ ++N + EL + + +++E I + + ++KA QL E+Q Sbjct: 338 MQL-AQAQKQIQELKN-QCELKMLEEK--QMKEQIIKESEIKVDSQQKAFQL-----EQQ 388 Query: 811 KAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLS 870 K+ E I+ EL + L + + ++++++ + +NK+L+ L ++ Q L+ L Sbjct: 389 KSEKEQQIR--ELKRDIEQLKEDLQDQKEKVIQEQQKNKDLKNNEYSLTKDIQTLEEQLQ 446 Query: 871 DMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEI 930 ++Q ++ L EK R A+ +S Q ++ + + + I + + I+Q K+ + LE Sbjct: 447 NIQNDHDKLQEKYAR---AQKQS---QKEIEESQMIIDEIKSQTEGEILQLTKKCQKLE- 499 Query: 931 EFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVE-ELNKMNLELI 989 +NE E+N++ V ++L+E+K + + E E K+N +L Sbjct: 500 --------------SINEDLEQNLKIV---RSELEEFKKKHGSTKLKYEDEFVKVN-QLQ 541 Query: 990 DKHVQKQQT--QSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYE 1047 K +++ T Q + E + + KL L + E+ ++Q+ N Q+ M VSD + Sbjct: 542 RKLDEREDTIKQQKEQIETHKLKEQKLTEQLGKIQEQTKIISQEKEN-QLREMIKVSDMK 600 Query: 1048 SKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIP 1107 KLA+ ++E E EM+ + ++++ + ++ +++E D Q E++ LT + + Sbjct: 601 VKLAE--RQMEQKENEMKLLREEMVYLSEQLDQGSEVMKEYDRQCIEIE--MLTQQKDQL 656 Query: 1108 KTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLK--VQEEEEFIQERSVLQEQSAKLN 1165 + MI+ I+ + + + L+ V ++E IQE + + Sbjct: 657 QQTIMILEKQIDEKNLEFMQLQQAYRDIEIDREKLQETVIKQESIIQEAKQTENHIREEK 716 Query: 1166 TELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSIS 1225 ++ E + ++ + ++ E V ++Q +L KL+ E LL + + + + Sbjct: 717 RKVIEQFKQVSYEKRISDEKALVTEVVEKQNEELLQKLDSTRNEMKQLLEQLRQEKLQVE 776 Query: 1226 SAVDQ---RGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEE 1282 ++ + I EL + R +K + E R+++ + K+E + V + Q E Sbjct: 777 KLTEENEKQNQRIKELEESQSVMRAIQSEKEKEESRLEVEMLKMKHESM---VSLNKQYE 833 Query: 1283 TNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXX 1342 + + + L+ L++ + + LQ++ + QI LR E++ Sbjct: 834 DEILQLSKDIQELEKSLKNSYKRINALQQEIEEKEQQISDLRKELDLVDRQVILKINHEK 893 Query: 1343 XXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKV 1402 DL+ E + + +Q+Q L + +A+ ++ D + K+ Sbjct: 894 SQYQTQVTDLQLEVEQMRNLQQQIAL-LKSNDAKYIETIASLQKEINKLEIDNQDLQFKI 952 Query: 1403 LELTHQLELKDSEIYQKTH----EYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESE 1458 + QL+ + Q H ++ I L + + + R Q++E + + YE++++ Sbjct: 953 KQQDLQLQKTEIAFNQNIHYQASQHVIDLETQIHQ-QQARNQILEQQLKAMTEKYEQKAK 1011 Query: 1459 LAILRLKMHENANHYETMQKESEI-ERVKLIEELNVKITESVSLNKQVAELNKALEEEVA 1517 L R ++ + H Q +I + ++ ++ ++ N L Sbjct: 1012 L-FERYGVNFDPQHPNYNQTVKKIPQPTNMLTSPPFSPRKNQVSTASISNNNNPLFLSPP 1070 Query: 1518 KTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQ 1566 + + Q L NQ+ + + QN++ + SS+ Q+ +F+S Q Sbjct: 1071 QKLQSQNLLFNQQ----AIPNSSQQTQNLIYSPSSQNQEQFNFSSRQNQ 1115 Score = 119 bits (286), Expect = 8e-25 Identities = 179/915 (19%), Positives = 392/915 (42%), Gaps = 89/915 (9%) Query: 672 SASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEK 731 SA K++ N D Y L N +++ + I N + +KLEK Sbjct: 21 SAQKRQYTFTFNNESKDLSS-YQAGSSLFNMSQELKYSTPS-ILNNQEKEEKLEK----- 73 Query: 732 ISELLAKINHEEQSKIQTQFGIDAKIQERDLYIEN---------IESELSKYKSRICR-- 780 I ++ +++ +Q K+Q + ++ L EN +E ++ +Y+ + Sbjct: 74 IRQMESRMKQLQQEKMQIDLSVSETVERTQLVQENNDLKNQLYAMELQIKQYQQHQQQDL 133 Query: 781 LEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDE---LVNRLAVLMDHDRVV 837 E S+++ + ++ E K +QL ++E ++ + + + L+ + V H +V+ Sbjct: 134 TEVSLSLEKQKQIEFENKVNQL---VKENANLIEQFNMAKQDLELLIKQKEVDRAHIQVL 190 Query: 838 EKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQ 897 E++LL E N++L++KN L +E +Q Y++ ++ DL K Sbjct: 191 EEKLLAFERMNEKLEEKNIQLRDEMIKIQ---------YHSNTDENYVQDL--KNQYKRV 239 Query: 898 TQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYV 957 L DLE K++ Q ++ ++ LE+E+ T ++ + K LN+ E IE Sbjct: 240 NDLLDLELKNKKVYEMQLIQAKQSQQSLKQLELEY-TSLQQNLEKLKKLNQ--ELTIENN 296 Query: 958 TQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNAL 1017 T + Q Y N +N+ + E N + + + K + Q + D Q ++ L Sbjct: 297 T---IKQQYYSENQKNI---ILEKNSLKIYQLQKELDISQQNTQDIQMQLAQAQKQIQEL 350 Query: 1018 LKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQH 1077 Q E+ L +K Q+ S + +S+ F + + E+E Q++ + D +Q Sbjct: 351 KNQC--ELKMLEEKQMKEQIIKESEIK-VDSQQKAFQLEQQKSEKE-QQIRELKRDIEQL 406 Query: 1078 NEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXX 1137 E+L QD + K ++E + ++ K ++ I+ + + N+ Sbjct: 407 KEDL------QDQKEKVIQEQQKNKDL---KNNEYSLTKDIQTLEEQLQNIQNDHDKLQE 457 Query: 1138 XXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQIN 1197 + Q ++E + + ++ E ++ E+ + K +LE++N +L + + + ++ Sbjct: 458 KYARAQKQSQKEIEESQMIIDEIKSQTEGEILQLTKKCQKLESINEDLEQNLKIVRSELE 517 Query: 1198 QLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHEL 1257 + K K + ++ V +L+ + D + ++ L +++ Q + + Sbjct: 518 EFKKKHGSTKLKYEDEFVKVNQLQRKLDEREDTIKQQKEQIETHKLKEQKLTEQLGKIQE 577 Query: 1258 RVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVI 1317 + ++ + + K QL + ++ S + MEQ + L+++ +L ++ ++V+ Sbjct: 578 QTKIIS-QEKENQLREMIKVSDMKVKLAERQMEQKENEMKLLREEMVYLSEQLDQGSEVM 636 Query: 1318 NQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQL 1377 + + R IE E + D +N + Q+Q Q+ +I + +L Sbjct: 637 KEYD--RQCIEIEMLTQQKDQLQQTIMILEKQID--EKNLEFMQLQ-QAYRDIEIDREKL 691 Query: 1378 KKS---SXXXXXXXXXXXXRVNDAEAKVLE----LTHQLELKD-----SEIYQKTHEYTI 1425 +++ + + + KV+E ++++ + D +E+ +K +E + Sbjct: 692 QETVIKQESIIQEAKQTENHIREEKRKVIEQFKQVSYEKRISDEKALVTEVVEKQNEELL 751 Query: 1426 -TLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIER 1484 L +E + + +QL + + ++E LT E E + ++ ++ E+ + +Q E E E Sbjct: 752 QKLDSTRNEMKQLLEQLRQEKLQVEKLTEENEKQNQRIK-ELEESQSVMRAIQSEKEKEE 810 Query: 1485 VKL-IEELNVKITESVSLNKQ-----------VAELNKALEEEVAKTNEMQTALENQEIE 1532 +L +E L +K VSLNKQ + EL K+L+ + N +Q +E +E + Sbjct: 811 SRLEVEMLKMKHESMVSLNKQYEDEILQLSKDIQELEKSLKNSYKRINALQQEIEEKEQQ 870 Query: 1533 IVTLNDEITNLQNMV 1547 I L E+ + V Sbjct: 871 ISDLRKELDLVDRQV 885 Score = 116 bits (280), Expect = 4e-24 Identities = 192/984 (19%), Positives = 437/984 (44%), Gaps = 95/984 (9%) Query: 337 QIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQ 396 Q+ Q N +L+N+L M + K ++ +S + + ++ +QL E N Sbjct: 103 QLVQENNDLKNQLYAMELQIKQYQQHQQQDLTEVSLSLEKQKQIEFENKVNQLVKENANL 162 Query: 397 DTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEH 456 + K + LE++I+ D + V+ EK K+ + ++ Sbjct: 163 IEQFNMAKQD---LELLIKQKEVDRAHIQ-VLEEKLLAFERMNEKLEEKNIQLRDEMIKI 218 Query: 457 QQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDL-IEKLKSAEEQITQL 515 Q H T+ V ++ +++ L+ E+K+ V ++ + + K +++ + QL Sbjct: 219 QYHSN--------TDENYVQDLKNQYKRVNDLLDLELKNKKVYEMQLIQAKQSQQSLKQL 270 Query: 516 NDEIDAANKNMIKVKS-NHKLKLKQMQKTIDNFSKVSDSNKEIV--RLTEELHHLSQKVA 572 E + +N+ K+K N +L ++ TI S++ K I+ + + +++ L +++ Sbjct: 271 ELEYTSLQQNLEKLKKLNQELTIEN--NTIKQ-QYYSENQKNIILEKNSLKIYQLQKELD 327 Query: 573 ELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQ-KFDLVQELH 631 ++ ++Q+ L + + I+ K E++ L E ++K + ES+ K D Q+ Sbjct: 328 ISQQNTQDIQMQLAQ--AQKQIQE--LKNQCELKMLEEKQMKEQIIKESEIKVDSQQKAF 383 Query: 632 ILQQKYDEVEDKLA----DISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKL 687 L+Q+ E E ++ DI QL+ D + K + +++ L ++ L I+ L+ Sbjct: 384 QLEQQKSEKEQQIRELKRDIEQLKEDLQDQKEKVIQEQQKNKDLKNNEYSLTKDIQTLEE 443 Query: 688 DKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKI 747 + + L+ + Q I+E+ + D+++ + +I +L K ++ I Sbjct: 444 QLQNIQNDHDKLQEKYARAQKQSQKEIEESQMIIDEIKSQTEGEILQLTKKC--QKLESI 501 Query: 748 QTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQ 807 + KI +L E K+ S + E+ + L+RK D+ ++ Sbjct: 502 NEDLEQNLKIVRSEL-----EEFKKKHGSTKLKYEDEFVKVN----QLQRKLDEREDTIK 552 Query: 808 EKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKN--QILLEENQNL 865 ++++ + ++E +L +L + + +++ + E E++ +E+ K + ++ L E Q + Sbjct: 553 QQKEQIETHKLKEQKLTEQLGKIQEQTKIISQ---EKENQLREMIKVSDMKVKLAERQ-M 608 Query: 866 QISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEI 925 + ++M+ +V + + D +Y Q ++E ++ QT+++ +K+I Sbjct: 609 EQKENEMKLLREEMVYLSEQLDQGSEVMKEYDRQCIEIEMLTQQKDQLQQTIMI-LEKQI 667 Query: 926 EDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMN 985 ++ +EF Q++ A RD ++ EK + E V + E+ +QE K EN ++ E Sbjct: 668 DEKNLEF-MQLQQAYRDIEIDREKLQ---ETVIKQESIIQEAKQT-EN---HIRE----- 714 Query: 986 LELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSD 1045 +K +Q + Y ++ +E + ++++++EE++ QK+++ + ++ Sbjct: 715 ----EKRKVIEQFKQVSYEKRISDEKALVTEVVEKQNEELL---QKLDSTRNEMKQLLEQ 767 Query: 1046 YESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMN 1105 + Q E E++ QR+ K+L EE Q ++R + KE +E++L EM Sbjct: 768 LRQEKLQVEKLTEENEKQNQRI-KEL-------EESQSVMRAIQSE-KEKEESRLEVEML 818 Query: 1106 IPKTEGMI-----ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQ 1160 K E M+ I +S D ++ L+ QE EE Q+ S L+++ Sbjct: 819 KMKHESMVSLNKQYEDEILQLSKDIQELEKSLKNSYKRINALQ-QEIEEKEQQISDLRKE 877 Query: 1161 SAKLNTE-LQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAE 1219 ++ + + + + Q +T T+L + EQ+ L+ ++ L + + + T+A Sbjct: 878 LDLVDRQVILKINHEKSQYQTQVTDLQ----LEVEQMRNLQQQIALLKSNDAKYIETIAS 933 Query: 1220 LRSSISS-AVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSS 1278 L+ I+ +D + + + Q++ QKTE + S++ ++D Sbjct: 934 LQKEINKLEIDNQDLQF------KIKQQDLQLQKTEIAFNQNIHYQASQH--VIDLETQI 985 Query: 1279 TQEETNKIVTMEQVTSLQNKLQDK 1302 Q++ + +Q+ ++ K + K Sbjct: 986 HQQQARNQILEQQLKAMTEKYEQK 1009 Score = 95.5 bits (227), Expect = 1e-17 Identities = 171/885 (19%), Positives = 376/885 (42%), Gaps = 54/885 (6%) Query: 212 EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271 E+ Q+ K N I K + + L+K E I LEE KLL R LE Sbjct: 149 ENKVNQLVKENANLIEQFNMAKQDLELLIKQKEVDRAHIQVLEE--KLLAFERMNEKLEE 206 Query: 272 S--KLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIE 329 +L E+ + L Q + E++ K E+ + + + + Sbjct: 207 KNIQLRDEMIKIQYHSNTDENYVQDLKNQYKRVNDLLDLELKNKKVYEM-QLIQAKQSQQ 265 Query: 330 LLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQL 389 L+ L + + LE KL + E ++ K+ S K QL Sbjct: 266 SLKQLELEYTSLQQNLE-KLKKLNQELTIENNTIKQ--QYYSENQKNIILEKNSLKIYQL 322 Query: 390 SSE-TLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTL 448 E ++Q + I + ++A+ + IQ L K ++ EK D+ Sbjct: 323 QKELDISQQNTQDI-QMQLAQAQKQIQELKNQCELK--MLEEKQMKEQIIKESEIKVDSQ 379 Query: 449 IAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQ---LKQELNDEIKDVNVKDLIEKL 505 QLE Q+ + + + + E + E + Q++ +Q+ N ++K+ N L + + Sbjct: 380 QKAFQLEQQKSEKEQQIRELKRDIEQLKEDLQDQKEKVIQEQQKNKDLKN-NEYSLTKDI 438 Query: 506 KSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELH 565 ++ EEQ+ + ++ D + + + + ++++ Q ID S + EI++LT++ Sbjct: 439 QTLEEQLQNIQNDHDKLQEKYARAQKQSQKEIEESQMIIDEIK--SQTEGEILQLTKKCQ 496 Query: 566 HLSQKVAELEEE----KGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLES 621 L +LE+ + L+ + S ++ D + K+ +++ + R I + Sbjct: 497 KLESINEDLEQNLKIVRSELEEFKKKHGSTKLKYEDEFVKVNQLQRKLDEREDTIKQQKE 556 Query: 622 QKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKK--ELA 679 Q + L ++ +++++ ISQ + +Q+ IK ++ ++ +K E+ Sbjct: 557 QIETHKLKEQKLTEQLGKIQEQTKIISQEKENQLREMIKVSDMKVKLAERQMEQKENEMK 616 Query: 680 LVIENLKLDKEQL-YGTIKDLENDKEDIMNKLQNYIQENMDLTDK-LEKMSAEKISELLA 737 L+ E + EQL G+ E D++ I ++ ++ + T LEK EK E + Sbjct: 617 LLREEMVYLSEQLDQGSEVMKEYDRQCIEIEMLTQQKDQLQQTIMILEKQIDEKNLEFMQ 676 Query: 738 KINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLER 797 +I + K+QE + E+I E + ++ I R E+ + + ++ S E+ Sbjct: 677 LQQAYRDIEIDRE-----KLQETVIKQESIIQEAKQTENHI-REEKRKVIEQFKQVSYEK 730 Query: 798 KADQLGSYLQEKQKAYSEYTIQE-DELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQ 856 + + + E + +E +Q+ D N + L++ + ++ L++E +E +K+NQ Sbjct: 731 RISDEKALVTEVVEKQNEELLQKLDSTRNEMKQLLEQ---LRQEKLQVEKLTEENEKQNQ 787 Query: 857 IL--LEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEH 914 + LEE+Q++ ++ ++ + +E + Q D L + E Sbjct: 788 RIKELEESQSVMRAIQSEKEKEESRLE-VEMLKMKHESMVSLNKQYEDEILQLSKDIQEL 846 Query: 915 QTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENL 974 + + K I L+ E + E I D + + ++ + + ++ + +Y+ + +L Sbjct: 847 EKSLKNSYKRINALQQEIEEK-EQQISDLRKELDLVDRQV--ILKINHEKSQYQTQVTDL 903 Query: 975 NMNVEELNKMNLEL-IDKHVQKQQTQSPDYTEQYINEI----NKLNALLKQKDEEI---- 1025 + VE++ + ++ + K + ++ ++ IN++ L +KQ+D ++ Sbjct: 904 QLEVEQMRNLQQQIALLKSNDAKYIETIASLQKEINKLEIDNQDLQFKIKQQDLQLQKTE 963 Query: 1026 IALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQ 1070 IA NQ I + Q S V D E+++ Q + + +E++++ ++++ Sbjct: 964 IAFNQNI-HYQAS--QHVIDLETQIHQQQARNQILEQQLKAMTEK 1005 Score = 81.4 bits (192), Expect = 2e-13 Identities = 136/742 (18%), Positives = 313/742 (42%), Gaps = 65/742 (8%) Query: 847 ENKELQKKN-QILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLES 905 EN+E +N Q L Q Q + + + + +A + S+ KY T L + Sbjct: 6 ENEEFGDENSQNLHNSAQKRQYTFTFNNESKDLSSYQAGSSLFNMSQELKYSTP-SILNN 64 Query: 906 NLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYE-KNIEYVTQLEAQL 964 K E + + K+++ +++ + + + +++ E + KN Y +E Q+ Sbjct: 65 QEKEEKLEKIRQMESRMKQLQQEKMQIDLSVSETVERTQLVQENNDLKNQLYA--MELQI 122 Query: 965 QEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEE 1024 ++Y+ + + ++L +++L L + + + + ++ N I + N + ++D E Sbjct: 123 KQYQQHQQ------QDLTEVSLSLEKQKQIEFENKVNQLVKENANLIEQFN--MAKQDLE 174 Query: 1025 IIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQIL 1084 ++ ++++ A + + E KL F E +EE+ ++ +++ + H+ + Sbjct: 175 LLIKQKEVDRAHIQVL------EEKLLAFERMNEKLEEKNIQLRDEMIKIQYHSNTDENY 228 Query: 1085 VREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKV 1144 V++ +Q K + + L E+ K M + + ++ LK Sbjct: 229 VQDLKNQYKRVNDL-LDLELKNKKVYEMQLIQA-KQSQQSLKQLELEYTSLQQNLEKLKK 286 Query: 1145 QEEEEFIQERSVLQEQSAK--LNTELQECYTKIIQLET------LNTELTGHDVVN-QEQ 1195 +E I+ ++ Q+ ++ N L++ KI QL+ NT+ + Q+Q Sbjct: 287 LNQELTIENNTIKQQYYSENQKNIILEKNSLKIYQLQKELDISQQNTQDIQMQLAQAQKQ 346 Query: 1196 INQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEH 1255 I +LK++ E E + + + S I Q+ F++ +Q +++E ++ + Sbjct: 347 IQELKNQCELKMLEEKQMKEQIIK-ESEIKVDSQQKAFQL----EQQKSEKEQQIRELKR 401 Query: 1256 ELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYAD 1315 ++ + + E+++ Q + + N+ + + +L+ +LQ+ + LQEKYA Sbjct: 402 DIEQLKEDLQDQKEKVIQEQQKNKDLKNNEYSLTKDIQTLEEQLQNIQNDHDKLQEKYAR 461 Query: 1316 VINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENA 1375 Q + EIE+ ++ + + +S + EQ++ + E Sbjct: 462 AQKQSQ---KEIEESQMIIDEIKSQTEGEILQLTKKCQ-KLESINEDLEQNLKIVRSELE 517 Query: 1376 QLKKSSXXXXXXXXXXXXRVNDAEAKVLEL------------THQL-ELKDSEIYQKTHE 1422 + KK +VN + K+ E TH+L E K +E K E Sbjct: 518 EFKKKHGSTKLKYEDEFVKVNQLQRKLDEREDTIKQQKEQIETHKLKEQKLTEQLGKIQE 577 Query: 1423 YTITLTQRNDEFENVRQQLVEYE----KRIEDLTYEKESELAILRLKMHENANHYETMQK 1478 T ++Q E EN +++++ K E +KE+E+ +LR E E + + Sbjct: 578 QTKIISQ---EKENQLREMIKVSDMKVKLAERQMEQKENEMKLLR---EEMVYLSEQLDQ 631 Query: 1479 ESEI--ERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTL 1536 SE+ E + E+ + + L + + L K ++E+ + ++Q A + EI+ L Sbjct: 632 GSEVMKEYDRQCIEIEMLTQQKDQLQQTIMILEKQIDEKNLEFMQLQQAYRDIEIDREKL 691 Query: 1537 NDEITNLQNMVRASSSKIQKHV 1558 + + +++++ + + + H+ Sbjct: 692 QETVIKQESIIQ-EAKQTENHI 712 Score = 81.0 bits (191), Expect = 2e-13 Identities = 151/809 (18%), Positives = 355/809 (43%), Gaps = 56/809 (6%) Query: 149 NTIKEKDNALSV--LQVKMKIMETTILDLQEKINE-KDQIIEAKNKATTXXXXXXXXXXX 205 N I EK N+L + LQ ++ I + D+Q ++ + + QI E KN+ Sbjct: 309 NIILEK-NSLKIYQLQKELDISQQNTQDIQMQLAQAQKQIQELKNQCELKMLEEKQMKEQ 367 Query: 206 XXXXXX--EDTKQQMTKMQENFIAMEAEWKDEK---QRLLKDIESKDVRISSLEEANKLL 260 D++Q+ ++++ E + ++ K ++L +D++ + ++ ++ NK L Sbjct: 368 IIKESEIKVDSQQKAFQLEQQKSEKEQQIRELKRDIEQLKEDLQDQKEKVIQEQQKNKDL 427 Query: 261 EAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIAN 320 + + ++ + L ++L+ KQS + E + I+E S Sbjct: 428 KNNEYSLTKDIQTLEEQLQNIQNDHDKLQEKYARAQKQSQKEIEESQMIIDEIKSQTEGE 487 Query: 321 MTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTAS 380 + +LTKK + LE +N + Q K + ++L E K K GS + + + Sbjct: 488 ILQLTKKCQKLESINEDLEQNLKIVRSEL----EEFK-----KKHGSTKLKYEDEFVKVN 538 Query: 381 KMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXX 440 +++ + +T+ Q + +I +++ K + + + L K + ++ +IS++ Sbjct: 539 QLQRKLDE-REDTIKQQKE-QIETHKL-KEQKLTEQLGK-IQEQTKIISQEKENQLREMI 594 Query: 441 XXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKD 500 +A+ Q+E +++ + +E +++ ++V ++ ++ + ++ Sbjct: 595 KVSDMKVKLAERQMEQKENEMKLLREEMVYLSEQLDQGSEVMKEYDRQC------IEIEM 648 Query: 501 LIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHK---LKLKQMQKTIDNFSKVSDSNKEI 557 L ++ ++ I L +ID N ++++ ++ + +++Q+T+ + K+ Sbjct: 649 LTQQKDQLQQTIMILEKQIDEKNLEFMQLQQAYRDIEIDREKLQETVIKQESIIQEAKQ- 707 Query: 558 VRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIE-MENLAETRLKAI 616 TE +H+ ++ ++ E+ + D ++ V K+ E ++ L TR + Sbjct: 708 ---TE--NHIREEKRKVIEQFKQVSYEKRISDEKALVTEVVEKQNEELLQKLDSTRNEMK 762 Query: 617 SLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKK 676 LLE + + +Q + L ++ ++ ++ ++ + QS + + E +++ K Sbjct: 763 QLLEQLRQEKLQ-VEKLTEENEKQNQRIKELEESQSVMRAIQSEKEKEESRLEVEMLKMK 821 Query: 677 ELALVIENLKLDKE--QLYGTIKDLENDKEDI---MNKLQNYIQENMDLTDKLEKMSAEK 731 ++V N + + E QL I++LE ++ +N LQ I+E L K Sbjct: 822 HESMVSLNKQYEDEILQLSKDIQELEKSLKNSYKRINALQQEIEEKEQQISDLRKELDLV 881 Query: 732 ISELLAKINHEEQSKIQTQF-GIDAKIQE-RDL--YIENIESELSKYKSRICRLEESIAV 787 +++ KINH E+S+ QTQ + ++++ R+L I ++S +KY I L++ I Sbjct: 882 DRQVILKINH-EKSQYQTQVTDLQLEVEQMRNLQQQIALLKSNDAKYIETIASLQKEINK 940 Query: 788 MEDRRYSLERKADQLGSYLQEKQKAYSE-YTIQEDELVNRLAVLMDHDRVVEKQLLEIEH 846 +E L+ K Q LQ+ + A+++ Q + V L + H + Q+L E Sbjct: 941 LEIDNQDLQFKIKQQDLQLQKTEIAFNQNIHYQASQHVIDLETQI-HQQQARNQIL--EQ 997 Query: 847 ENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESN 906 + K + +K + + + ++ +YN V+K + + T R + + Sbjct: 998 QLKAMTEKYEQKAKLFERYGVNFDPQHPNYNQTVKKIPQ---PTNMLTSPPFSPRKNQVS 1054 Query: 907 LKRITHEHQTLIVQKKKEIEDLEIEFNTQ 935 I++ + L + ++++ + FN Q Sbjct: 1055 TASISNNNNPLFLSPPQKLQSQNLLFNQQ 1083 >UniRef50_Q52L24 Cluster: LOC733209 protein; n=1; Xenopus laevis|Rep: LOC733209 protein - Xenopus laevis (African clawed frog) Length = 1713 Score = 126 bits (305), Expect = 4e-27 Identities = 246/1317 (18%), Positives = 553/1317 (41%), Gaps = 129/1317 (9%) Query: 309 EIEEKGSLEIANMTELTKKIE-LLEHLNCQIRQTNKELE-NKLATMGTESKAVSSPSKKG 366 EI+EK LEI ++++ L++L + +T + ++A + + + + Sbjct: 414 EIQEKHELEIQEKCLTVQQLQHQLQNLGNNVGETAQPTNITEMAVVKLQDEVKLKTEESQ 473 Query: 367 SPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEY 426 + N +++ +L ++ + IN+ +AKL + + K D E Sbjct: 474 GKNQDLRGLSNRIVELEEEKHELETKLKTLTELQAINEQLLAKLVLYEEQQRKLQADLEQ 533 Query: 427 VISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLK 486 V D+ + L+ ++ + E P ++E+ + +A Q++ Sbjct: 534 VAKRADSQTSESGSVDELHNQLLEWNEMSPEME-EAPE-----NSSEEKSVLALRMAQIE 587 Query: 487 QELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLK---QMQKT 543 +E E D ++L E+L SA + ++ +K K++ K T Sbjct: 588 EER--EAMDSGQQELEEEL-SAARGLGKMRPARRKGSKAATKMQEEDDYSRKGFDDQNVT 644 Query: 544 IDNFSKVSDSNKEIVR-LTEEL----HHLSQKVAELE------EEKGNLQLHLVDYDS-G 591 +D+ N +R + EEL + L +++ LE E++ LQL + Sbjct: 645 LDSIDSAEGENMGGLRTVVEELELERNQLQEQIMSLEDRCQELEDRLQLQLRIESLQGEN 704 Query: 592 RMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVED-------KL 644 +++ + + + E + S L Q L+ E E KL Sbjct: 705 ERLQAQLGQLRQQQNRETEKQHSFTSTLSEQLKGFTDRNAFLENVIAEKEQIILEAAGKL 764 Query: 645 ADISQLQSDQVCSEIKSVHLEEQIDA----LSASKKELALV---IENLKLDKEQLY---G 694 ++++L+ E + + E++D L + K+LA++ + LKL +L Sbjct: 765 EELARLKKILKEKEDLNKAIAEKLDQSELQLEETSKKLAVLETESQALKLSNNELTEKAA 824 Query: 695 TIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGID 754 T+K+ ++ + K+Q +++ + D+L E+ S+L+ + E+ + Sbjct: 825 TLKEKLLKQDAALEKMQLDLEQTNEELDRLNTSHLEERSQLIYDLQRCEREMDVLR---- 880 Query: 755 AKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYS 814 +QE+D + ++ S L++Y ++ L+E I + ++ + +D L +E Q Sbjct: 881 EVLQEKDKELASLSSSLTEYNEQVVILKEQIDLKNEQ---MREMSDALVKAERESQLLRE 937 Query: 815 EYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQ 874 T E+ ++++ L D ++ +L + ++ ++ K+ + L+ + I++ +++ Sbjct: 938 AQTSDTREMSDKISSLTDQLSEMDMELNKAKYLSETKAKEAEELIRQINENGITIKNLRS 997 Query: 875 HYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNT 934 A + A + A ST+ + + + +++ ++ E +T + +KEIE L+++ + Sbjct: 998 EIQA--QSATHNNHAIECSTQITSLKQQINASVAKLD-ETET---KYRKEIESLKLQLES 1051 Query: 935 QIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDK--- 991 + + +L EK + + +L+ ++Y N + ++ EE+ K+ E+ ++ Sbjct: 1052 DVSEREKIAGLLAEKSSQERSFENELKVAKEQYNNLVSGISKKDEEIEKLLTEVAEQKKF 1111 Query: 992 --HVQKQ-QTQSPDYT---EQYINEINKLNALLKQKDEEIIALN-------QKINNAQVS 1038 H++K+ Q + D + E+ + +I L+ E AL IN + + Sbjct: 1112 CDHLRKELQIKEKDASSLQEKLLADIKDREEKLRGFQESTQALQAQLSEKLDNINKSDAT 1171 Query: 1039 YMSMVSDYESKLAQFTTKLENMEEEM---QRVSKQLLDSKQHNEELQILVREQDDQIKEL 1095 +V + + K +N+E + + K +L+ +QHN++ L+ E++ KEL Sbjct: 1172 KNELVEQNKILKTALSEKDKNLEVHLTATEECRKSILELEQHNQQ---LLNEKEHLAKEL 1228 Query: 1096 KETK-----LTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQ--EEE 1148 E K L E+NI + + + +E D NN D L+ Q EE Sbjct: 1229 SEQKQFYDDLKKELNIKEENSLCLQQKLEM---DINNRDEKLTVLEERVLELQKQLDEEL 1285 Query: 1149 EFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNT 1208 E I + +++ K N L+ + + + L+ L + ++ I L+ + +QL + Sbjct: 1286 ENIHNLNTAKDELDKRNKILEVALAE--REKNLSVHLNKTEEC-RKHILDLEQQKQQLYS 1342 Query: 1209 ENDNLLSTVAELRSSIS------SAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLS 1262 E ++L+ +A+ + A +Q+ + + + HL R+ + + + Sbjct: 1343 EKEHLVEELAKQKQCCDHLTAELQATEQKASTLQQKHEAHLKDRDELLRVLQESTQKLQK 1402 Query: 1263 AFESKYEQL--LDSVQSSTQEETNKIVTM-----EQVTSLQNKLQDKEEHLRNLQEKYAD 1315 E K E + LD+ ++ E+ K+ + E + QN ++ ++ +L+++ Sbjct: 1403 QLEEKVEHINTLDAAKNGLCEQNKKLESSLAEKNENLGVYQNSAEELRRNIVDLEQQKQQ 1462 Query: 1316 VINQIEILRSEI---EDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQM---QEQSILN 1369 + ++ E +R E+ E ++ L E + Q+ +E+ L Sbjct: 1463 LHSEKEHIRQELSARESALLSLNQVLHDLQGKMSEMELLLMEEKKWVSQLTLDKEELQLK 1522 Query: 1370 IN-------EENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQL-----ELKDSE-- 1415 I+ E + + K ++++ + L +Q+ +LK+S+ Sbjct: 1523 ISHMSEQSLERDTVISKQLEDKALESFSLKDQLSEEKQNAKNLLNQIHVQENQLKESQKR 1582 Query: 1416 IYQKTHEYTITLTQRNDEFENVRQ---QLVEYEKRIEDLTYEKESELAILRLKMHENANH 1472 + Q E + + N FE+++Q + VE +K +E+LT E L+ ++ + Sbjct: 1583 VQQSVEELELMKVEYNTIFESLKQNEERNVELQKHVEELTTALGRENQALKAELEQWKAS 1642 Query: 1473 YETMQKESEIERVKLIEELNVKITE-SVSLNKQVAELNKALEEEVAKTNEMQTALEN 1528 + +Q E I R + + ++++ITE S L K + ++ +E V KT E + L++ Sbjct: 1643 FAALQNEENILREE-HKRVSLQITELSAELLKLNVDQDRLQQEAVQKTEENASLLKS 1698 Score = 120 bits (290), Expect = 3e-25 Identities = 257/1331 (19%), Positives = 547/1331 (41%), Gaps = 118/1331 (8%) Query: 320 NMTELTKKIELLEHLNCQIRQTNKELENKLATM---------GTESKAVSSPSKKGSPLI 370 ++ +LT+++ E L Q+++ +E +N+L ESK + + + ++ Sbjct: 38 SVADLTEQLAQTEQLVVQLKELIREKDNELRKKDQQLKEKRESAESKISKAKLQNKAKIV 97 Query: 371 SRKSGRNTASKMKS---PWSQLS-SETLNQDTD---KKINKNEIAKLEMVIQSLNKDLVD 423 S S K ++ P + S ++ + D D N+ +I L+ ++ L L Sbjct: 98 SLTSQLEELKKQQASSRPHEKKSENKKASGDGDYENSSANRGKILLLKRRVEELESQLAH 157 Query: 424 KEYVISEKDTXXXXXXXXXXGKDTLIAQLQ--LEHQQHMEGPSLIHVGTNTED--VNEIA 479 K + +K+ D ++++ + L ++ + G+NT + Sbjct: 158 KNEELQKKEADLEQQRLRGSQMDAMLSEKEQKLAAKEAYIIDLQMAAGSNTSKNVPSSQD 217 Query: 480 KVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQ 539 QE K + N E++ V +++L K+ ++E+ + L ++ ++ + K K + K + Sbjct: 218 NTQETNKDKANQELQ-VLIQNLTRKVGESDEKCSLLQEQAESLKTLLNKEKDHFKAREAM 276 Query: 540 MQKTIDNFSK-VSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLH-LVDYDSGRMIESD 597 + I F V + KE+ +++ H L + N LH L+ ++ E + Sbjct: 277 YTENIRVFQNLVQEKEKELKEQSQK--HEQDIFKLLAKSDANADLHQLLKALKQKLHEEE 334 Query: 598 VYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCS 657 + ++ + + K + E Q ++ ++ LQ + + ++ KL + Q+ Sbjct: 335 --EVLLGKNQVIDVLQKELDNKEQQNMEITEKCKRLQSEKENLQSKLEAEKHVMRAQL-R 391 Query: 658 EIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQEN 717 ++ H E ++ + E +L+ ++ T++ L++ + L N + E Sbjct: 392 DMMDKHETELRGLHDKHVAQIQEIQEKHELEIQEKCLTVQQLQHQ----LQNLGNNVGET 447 Query: 718 MDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSR 777 T+ + +M+ K+ + + E Q K Q G+ +I E +E E + +++ Sbjct: 448 AQPTN-ITEMAVVKLQDEVKLKTEESQGKNQDLRGLSNRIVE-------LEEEKHELETK 499 Query: 778 ICRLEESIAVMEDRRYSL---ERKADQLGSYLQEKQKAYSEYTIQE---DELVNRLAVLM 831 + L E A+ E L E + +L + L++ K T + DEL N+L Sbjct: 500 LKTLTELQAINEQLLAKLVLYEEQQRKLQADLEQVAKRADSQTSESGSVDELHNQLLEWN 559 Query: 832 DHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAES 891 + +E+ E L + + EE + + ++++ +A + A Sbjct: 560 EMSPEMEEAPENSSEEKSVLALRMAQIEEEREAMDSGQQELEEELSA-ARGLGKMRPARR 618 Query: 892 ESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYE 951 + +K T++++ E + R + Q + + I+ E E + + + + ++ + + Sbjct: 619 KGSKAATKMQE-EDDYSRKGFDDQNVTLD---SIDSAEGENMGGLRTVVEELELERNQLQ 674 Query: 952 KNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEI 1011 E + LE + QE ++ ++ L + +E L N L + Q +Q Q+ + TE+ + Sbjct: 675 ---EQIMSLEDRCQELEDRLQ-LQLRIESLQGENERLQAQLGQLRQQQNRE-TEKQHSFT 729 Query: 1012 NKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQL 1071 + L+ LK + L I + + E +LA+ L+ E+ + ++++L Sbjct: 730 STLSEQLKGFTDRNAFLENVIAEKEQIILEAAGKLE-ELARLKKILKEKEDLNKAIAEKL 788 Query: 1072 LDSKQHNEEL--QILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVD 1129 S+ EE ++ V E + Q +L +LT + K + + + +E M D + Sbjct: 789 DQSELQLEETSKKLAVLETESQALKLSNNELTEKAATLKEKLLKQDAALEKMQLDLEQTN 848 Query: 1130 XXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHD 1189 ++E + I + + + L LQE ++ L + TE Sbjct: 849 EELDRLNTS----HLEERSQLIYDLQRCEREMDVLREVLQEKDKELASLSSSLTEYNEQV 904 Query: 1190 VVNQEQINQLKSKLEQLN-----TENDNLL------STVAELRSSISSAVDQRGFEIAEL 1238 V+ +EQI+ ++ +++ E ++ L S E+ ISS DQ EL Sbjct: 905 VILKEQIDLKNEQMREMSDALVKAERESQLLREAQTSDTREMSDKISSLTDQLSEMDMEL 964 Query: 1239 WK-QHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTME-QVTSLQ 1296 K ++L++ +A K EL Q++ + L +Q+ + N + Q+TSL+ Sbjct: 965 NKAKYLSETKA---KEAEELIRQINENGITIKNLRSEIQAQSATHNNHAIECSTQITSLK 1021 Query: 1297 NKLQDKEEHLRNLQEKYADVINQIEI-LRSEI-EDEKVAFXXXXXXXXXXXXXXXXDLRT 1354 ++ L + KY I +++ L S++ E EK+A +L+ Sbjct: 1022 QQINASVAKLDETETKYRKEIESLKLQLESDVSEREKIA--GLLAEKSSQERSFENELKV 1079 Query: 1355 ENQSYKQM------QEQSILNINEENAQLKK-----------SSXXXXXXXXXXXXRVND 1397 + Y + +++ I + E A+ KK + D Sbjct: 1080 AKEQYNNLVSGISKKDEEIEKLLTEVAEQKKFCDHLRKELQIKEKDASSLQEKLLADIKD 1139 Query: 1398 AEAKV---LELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIE-DLTY 1453 E K+ E T L+ + SE ++ T + ++ + ++ L E +K +E LT Sbjct: 1140 REEKLRGFQESTQALQAQLSEKLDNINKSDATKNELVEQNKILKTALSEKDKNLEVHLTA 1199 Query: 1454 EKESELAILRLKMHEN--ANHYETMQKE-SEIERV--KLIEELNVKITESVSLNKQVAEL 1508 +E +IL L+ H N E + KE SE ++ L +ELN+K S+ L ++ Sbjct: 1200 TEECRKSILELEQHNQQLLNEKEHLAKELSEQKQFYDDLKKELNIKEENSLCLQQK---- 1255 Query: 1509 NKALEEEVAKTNEMQTALENQEIEI-VTLNDEITNLQNMVRASSSKIQKHVSFASDTKQG 1567 LE ++ +E T LE + +E+ L++E+ N+ N+ + ++ K Sbjct: 1256 ---LEMDINNRDEKLTVLEERVLELQKQLDEELENIHNL-NTAKDELDKRNKILEVALAE 1311 Query: 1568 RDEQLDNTMNK 1578 R++ L +NK Sbjct: 1312 REKNLSVHLNK 1322 Score = 119 bits (287), Expect = 6e-25 Identities = 223/1140 (19%), Positives = 478/1140 (41%), Gaps = 123/1140 (10%) Query: 469 GTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIK 528 G + + V +I ++QE K EL + K + V+ L +L++ + + + ++K Sbjct: 403 GLHDKHVAQIQEIQE--KHELEIQEKCLTVQQLQHQLQNLGNNVGETAQPTNITEMAVVK 460 Query: 529 VKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDY 588 ++ KLK ++ Q ++L LS ++ ELEEEK L+ L Sbjct: 461 LQDEVKLKTEESQGK-----------------NQDLRGLSNRIVELEEEKHELETKL--- 500 Query: 589 DSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADIS 648 K + E++ + E L + L E Q+ L +L + ++ D + + Sbjct: 501 -----------KTLTELQAINEQLLAKLVLYEEQQRKLQADLEQVAKRADSQTSESGSVD 549 Query: 649 QLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDI-- 706 +L + + S +EE + S K LAL + ++ ++E + ++LE + Sbjct: 550 ELHNQLLEWNEMSPEMEEAPENSSEEKSVLALRMAQIEEEREAMDSGQQELEEELSAARG 609 Query: 707 MNKLQNYIQENMDLTDKLEK---MSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLY 763 + K++ ++ K+++ S + + ++ + ++ + G+ ++E +L Sbjct: 610 LGKMRPARRKGSKAATKMQEEDDYSRKGFDDQNVTLDSIDSAEGENMGGLRTVVEELELE 669 Query: 764 IENIESELSKYKSRICRLEESIAV---MEDRRYSLERKADQLGSYLQEKQKAYSEYTIQE 820 ++ ++ + R LE+ + + +E + ER QLG Q++ + + Sbjct: 670 RNQLQEQIMSLEDRCQELEDRLQLQLRIESLQGENERLQAQLGQLRQQQNRETEKQHSFT 729 Query: 821 DELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALV 880 L +L D + +E + E E E K LEE L+ L + + A+ Sbjct: 730 STLSEQLKGFTDRNAFLENVIAEKEQIILEAAGK----LEELARLKKILKEKEDLNKAIA 785 Query: 881 EKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAI 940 EK ++++L E++K L LK +E + +K +++ ++ + +E Sbjct: 786 EKLDQSELQLEETSKKLAVLETESQALKLSNNE----LTEKAATLKEKLLKQDAALEKMQ 841 Query: 941 RDKKVLNEKYEK----NIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQ 996 D + NE+ ++ ++E +QL LQ + ++ L ++E DK + Sbjct: 842 LDLEQTNEELDRLNTSHLEERSQLIYDLQRCEREMDVLREVLQEK--------DKELASL 893 Query: 997 QTQSPDYTEQYI---NEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQF 1053 + +Y EQ + +I+ N +++ + ++ ++ + + S + K++ Sbjct: 894 SSSLTEYNEQVVILKEQIDLKNEQMREMSDALVKAERESQLLREAQTSDTREMSDKISSL 953 Query: 1054 TTKLENMEEEMQRVSKQLLDSK-QHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGM 1112 T +L M+ E+ + +K L ++K + EEL + E IK L+ +++ + + Sbjct: 954 TDQLSEMDMELNK-AKYLSETKAKEAEELIRQINENGITIKNLR-SEIQAQSATHNNHAI 1011 Query: 1113 IISSTIEPMSDDAN----NVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTEL 1168 S+ I + N +D LK+Q E + + ER E+ A L E Sbjct: 1012 ECSTQITSLKQQINASVAKLDETETKYRKEIESLKLQLESD-VSER----EKIAGLLAE- 1065 Query: 1169 QECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAV 1228 K Q + EL V +EQ N L S + + + E + LL+ VAE + Sbjct: 1066 -----KSSQERSFENELK----VAKEQYNNLVSGISKKDEEIEKLLTEVAEQKKFCDHL- 1115 Query: 1229 DQRGFEIAELWKQHLAQR-EADFQKTEHELR---VQLSAFESKYEQLLDSVQSSTQEETN 1284 ++ +I E L ++ AD + E +LR A +++ + LD++ S + N Sbjct: 1116 -RKELQIKEKDASSLQEKLLADIKDREEKLRGFQESTQALQAQLSEKLDNINKSDATK-N 1173 Query: 1285 KIVTMEQV--TSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXX 1342 ++V ++ T+L K ++ E HL +E ++ ++E ++ +EK Sbjct: 1174 ELVEQNKILKTALSEKDKNLEVHLTATEECRKSIL-ELEQHNQQLLNEKEHLAKELSEQK 1232 Query: 1343 XXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKV 1402 +L + ++ +Q++ ++IN + +L + D E Sbjct: 1233 QFYDDLKKELNIKEENSLCLQQKLEMDINNRDEKL-----TVLEERVLELQKQLDEE--- 1284 Query: 1403 LELTHQLELKDSEIYQKTHEYTITLTQRN-------DEFENVRQQLVEYEKRIEDLTYEK 1455 LE H L E+ ++ + L +R ++ E R+ +++ E++ + L EK Sbjct: 1285 LENIHNLNTAKDELDKRNKILEVALAEREKNLSVHLNKTEECRKHILDLEQQKQQLYSEK 1344 Query: 1456 ESELAILRLKMHENANHY--ETMQKESEIERVKLIEELNVKITESV--SLNKQVAELNKA 1511 E + L K + +H E E + ++ E ++K + + L + +L K Sbjct: 1345 EHLVEEL-AKQKQCCDHLTAELQATEQKASTLQQKHEAHLKDRDELLRVLQESTQKLQKQ 1403 Query: 1512 LEEEVAKTNEMQTAL-----ENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQ 1566 LEE+V N + A +N+++E +L ++ NL + + S+ ++++++ KQ Sbjct: 1404 LEEKVEHINTLDAAKNGLCEQNKKLE-SSLAEKNENL-GVYQNSAEELRRNIVDLEQQKQ 1461 Score = 105 bits (252), Expect = 1e-20 Identities = 184/956 (19%), Positives = 415/956 (43%), Gaps = 82/956 (8%) Query: 310 IEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPL 369 I EK + E +KK+ +LE + ++ +N EL K AT+ + K + + Sbjct: 784 IAEKLDQSELQLEETSKKLAVLETESQALKLSNNELTEKAATL--KEKLLKQDAALEKMQ 841 Query: 370 ISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVIS 429 + + ++ + + S+ + D + + E+ L V+Q +K+L ++ Sbjct: 842 LDLEQTNEELDRLNTSHLEERSQLI---YDLQRCEREMDVLREVLQEKDKELASLSSSLT 898 Query: 430 EKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQEL 489 E + K+ + ++ + E S + T D E++ L +L Sbjct: 899 EYNEQVVILKEQIDLKNEQMREMS-DALVKAERESQLLREAQTSDTREMSDKISSLTDQL 957 Query: 490 NDEIKDVN-VKDLIE-KLKSAEEQITQLNDE-IDAAN-KNMIKVKS----NHKL----KL 537 ++ ++N K L E K K AEE I Q+N+ I N ++ I+ +S NH + ++ Sbjct: 958 SEMDMELNKAKYLSETKAKEAEELIRQINENGITIKNLRSEIQAQSATHNNHAIECSTQI 1017 Query: 538 KQMQKTID-NFSKVSDSNKEIVRLTEELH-HLSQKVAELEEEKGNL---QLHLVDYDSGR 592 +++ I+ + +K+ ++ + + E L L V+E E+ G L +++ Sbjct: 1018 TSLKQQINASVAKLDETETKYRKEIESLKLQLESDVSEREKIAGLLAEKSSQERSFENEL 1077 Query: 593 MIESDVYKKMIEMENLAETRLKAI--SLLESQKF--DLVQELHILQQKYDEVEDK-LADI 647 + + Y ++ + + ++ + + E +KF L +EL I ++ +++K LADI Sbjct: 1078 KVAKEQYNNLVSGISKKDEEIEKLLTEVAEQKKFCDHLRKELQIKEKDASSLQEKLLADI 1137 Query: 648 ----SQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLE--- 700 +L+ Q ++ L E++D ++ S ++E K+ K L K+LE Sbjct: 1138 KDREEKLRGFQESTQALQAQLSEKLDNINKSDATKNELVEQNKILKTALSEKDKNLEVHL 1197 Query: 701 NDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQER 760 E+ + Q N L ++ E ++ E + + +++ I+ + + + Q+ Sbjct: 1198 TATEECRKSILELEQHNQQLLNEKEHLAKELSEQKQFYDDLKKELNIKEENSLCLQ-QKL 1256 Query: 761 DLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQE 820 ++ I N + +L+ + R+ L++ + + ++L D+L +K+ E + E Sbjct: 1257 EMDINNRDEKLTVLEERVLELQKQLDEELENIHNLNTAKDEL-----DKRNKILEVALAE 1311 Query: 821 DELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALV 880 E L+V ++ K +L++E + ++L + + L+EE L+ +Q + L Sbjct: 1312 RE--KNLSVHLNKTEECRKHILDLEQQKQQLYSEKEHLVEE-------LAKQKQCCDHLT 1362 Query: 881 EKANRTD-LAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESA 939 + T+ A + K++ L+D + L+ + Q L +K++E+ ++E +++A Sbjct: 1363 AELQATEQKASTLQQKHEAHLKDRDELLRVLQESTQKL----QKQLEE-KVEHINTLDAA 1417 Query: 940 IRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLEL-IDKHVQKQQT 998 K L E+ +K + + L Y+N+ E L N+ +L + +L +K +Q+ Sbjct: 1418 ---KNGLCEQNKKLESSLAEKNENLGVYQNSAEELRRNIVDLEQQKQQLHSEKEHIRQEL 1474 Query: 999 QSPDYTEQYINEI--------NKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKL 1050 + + +N++ +++ LL ++ + + L Q+ M + Sbjct: 1475 SARESALLSLNQVLHDLQGKMSEMELLLMEEKKWVSQLTLDKEELQLKISHMSEQSLERD 1534 Query: 1051 AQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKE--TKLTFEMNIPK 1108 + +LE+ E + QL + KQ+ + L + Q++Q+KE ++ + E+ + K Sbjct: 1535 TVISKQLEDKALESFSLKDQLSEEKQNAKNLLNQIHVQENQLKESQKRVQQSVEELELMK 1594 Query: 1109 TEGMIISSTIEPMSDDAN-----NVDXXXXXXXXXXXXLKVQEEE------EFIQERSVL 1157 E I +++ +++ N +V+ LK + E+ E ++L Sbjct: 1595 VEYNTIFESLK-QNEERNVELQKHVEELTTALGRENQALKAELEQWKASFAALQNEENIL 1653 Query: 1158 QEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNL 1213 +E+ +++ ++ E ++++L L V E+ L L+ +N D L Sbjct: 1654 REEHKRVSLQITELSAELLKLNVDQDRLQQEAVQKTEENASLLKSLDSINVVADTL 1709 Score = 77.0 bits (181), Expect = 4e-12 Identities = 160/850 (18%), Positives = 345/850 (40%), Gaps = 66/850 (7%) Query: 90 ISESLANTLKQKEILMEKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSN 149 +S SL +Q IL E+I E + S +V+ Q D +S+ Sbjct: 893 LSSSLTEYNEQVVILKEQIDLKNEQMREMSDALVKAERESQLLREA----QTSDTREMSD 948 Query: 150 TIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXX 209 I + LS ++ M++ + L + K E +++I N+ Sbjct: 949 KISSLTDQLS--EMDMELNKAKYLS-ETKAKEAEELIRQINENGITIKNLRSEIQAQSAT 1005 Query: 210 XXE---DTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFE 266 + Q+T +++ A A+ + + + K+IES +++ S + + E Sbjct: 1006 HNNHAIECSTQITSLKQQINASVAKLDETETKYRKEIESLKLQLESDVSEREKIAGLLAE 1065 Query: 267 ISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTK 326 S + EL+ ++K+ E + TE+ E+ EL Sbjct: 1066 KSSQERSFENELK---VAKEQYNNLVSGISKKDEEIE-KLLTEVAEQKKFCDHLRKELQI 1121 Query: 327 KIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPW 386 K + L ++ K+ E KL ++A+ + + I++ T +++ Sbjct: 1122 KEKDASSLQEKLLADIKDREEKLRGFQESTQALQAQLSEKLDNINKSDA--TKNELVEQN 1179 Query: 387 SQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKD 446 L + +D + +++ + I L + + +++EK+ D Sbjct: 1180 KILKTALSEKDKNLEVHLTATEECRKSILELEQ---HNQQLLNEKEHLAKELSEQKQFYD 1236 Query: 447 TLIAQLQLEHQQHMEGPSLIHVGTNTED------VNEIAKVQEQLKQELNDEIKDVN-VK 499 L +L ++ + + + + N D + ++Q+QL +EL + I ++N K Sbjct: 1237 DLKKELNIKEENSLCLQQKLEMDINNRDEKLTVLEERVLELQKQLDEEL-ENIHNLNTAK 1295 Query: 500 DLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVR 559 D ++K E ++ + + N + H L L+Q ++ + +S+ +E+ + Sbjct: 1296 DELDKRNKILEVALAEREKNLSVHLNKTEECRKHILDLEQQKQQL--YSEKEHLVEELAK 1353 Query: 560 LTEELHHLSQKVAELEEEKGNLQ----LHLVDYDS-GRMIESDVYKKMIEMENLAETRLK 614 + HL+ ++ E++ LQ HL D D R+++ K ++ E +++ Sbjct: 1354 QKQCCDHLTAELQATEQKASTLQQKHEAHLKDRDELLRVLQESTQK----LQKQLEEKVE 1409 Query: 615 AISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSAS 674 I+ L++ K L ++ L+ E + L + Q ++++ I V LE+Q L + Sbjct: 1410 HINTLDAAKNGLCEQNKKLESSLAEKNENLG-VYQNSAEELRRNI--VDLEQQKQQLHSE 1466 Query: 675 KKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISE 734 K+ + + +E ++ + +D + M++++ + E +L + +K E Sbjct: 1467 KEHIRQELS----ARESALLSLNQVLHDLQGKMSEMELLLMEEKKWVSQL---TLDK-EE 1518 Query: 735 LLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYS 794 L KI+H + ++ I +++++ L +++ +LS+ K L I V E++ Sbjct: 1519 LQLKISHMSEQSLERDTVISKQLEDKALESFSLKDQLSEEKQNAKNLLNQIHVQENQLKE 1578 Query: 795 LERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKK 854 +++ Q L+ + Y+ TI E ++ + +R VE Q +E L ++ Sbjct: 1579 SQKRVQQSVEELELMKVEYN--TIFE-------SLKQNEERNVELQ-KHVEELTTALGRE 1628 Query: 855 NQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEH 914 NQ L E + + S + +Q N L E+ R L + T+ +L L + R+ E Sbjct: 1629 NQALKAELEQWKASFAALQNEENILREEHKRVSL---QITELSAELLKLNVDQDRLQQE- 1684 Query: 915 QTLIVQKKKE 924 VQK +E Sbjct: 1685 ---AVQKTEE 1691 >UniRef50_Q7NBF8 Cluster: Putative uncharacterized protein; n=1; Mycoplasma gallisepticum|Rep: Putative uncharacterized protein - Mycoplasma gallisepticum Length = 1931 Score = 126 bits (305), Expect = 4e-27 Identities = 231/1182 (19%), Positives = 500/1182 (42%), Gaps = 115/1182 (9%) Query: 233 KDEKQRLLKDIESKDVRI-SSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXX 291 K+E ++ ++ + ++I S A++ + E+ + K + + Sbjct: 319 KNEVEKAKQNFNDQQLKILQSKANADQYFALRKIELENSYKKAKNAILEANKAHAKNVQE 378 Query: 292 XXXLAKQSIEPSCEEKTEIEEKGSLEIANMT-ELTKKIEL--LEHLNCQIRQTNKELENK 348 LA ++ + E+ L+IA+++ E +K L L +L +++Q + LE K Sbjct: 379 EQALANKNNKTQRLLNKLKEDYDRLKIASLSFESMRKQSLAALNNLQDELKQKHNLLERK 438 Query: 349 LATM-GTESKAVSSPSKKGSPLISRK-----SGRNTASKMKSPWSQLSSETLNQDT---D 399 G ++ +S S L+ +K N + K+ + L+ + D + Sbjct: 439 KHEQDGIVNEKISELEGYRSDLVDQKLKIEREKENQERRYKAAEASLNKKRQEIDELFLE 498 Query: 400 KKINKNEIAKLEMVIQSLNKDLVDK----EYVISEKDTXXXXXXXXXXGKDTLIAQLQLE 455 NE + E + + ++++ K E++ SE D I ++QL+ Sbjct: 499 ANTKLNEASLKENDLNNQKREILAKLRNLEHLKSEIDQRRRDLDQRELIDQQTIRKIQLD 558 Query: 456 HQQH---MEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVN--VKDLIEK---LKS 507 + ++ LI N E E+ + + +K++ D VN K L ++ LK Sbjct: 559 VESERADLQRILLIERKKNDERQQELLQYERDIKRQQTDFENTVNWEQKKLSQREKELKD 618 Query: 508 AEEQI----TQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEE 563 EQ+ +++ ++ID N+ + + + + + L QK + ++ S + + EE Sbjct: 619 GYEQLQLKQSEVQEKIDELNEEINRAQKSKQNSLVLEQKLKSDLEHLNLSKNYLDKQQEE 678 Query: 564 LHHLSQKVAELEEEKGNLQLHLVDYDSGRMIES-DVYKKMIEMENLAETRLKA-ISLLES 621 L+ S K+ E L + + D R E +Y+K ++ + + + +++ ++ Sbjct: 679 LNQKSDKMIE--------DLKVFERDLKRQKEDLSIYEKSLQQKEASLINFQNDVTVQKN 730 Query: 622 QKFDLVQELHI-LQQKYDEVEDKL----ADISQLQSDQVCSEIKSVHLEEQIDALSASKK 676 + + Q +H L+ K +E++L A+ + +D+ + ++E+I +L+ +K Sbjct: 731 EAYHKAQAIHQELELKKAAIENELRKLTAERKAVDADKEENTKLKKFIDEEIRSLANERK 790 Query: 677 ELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISEL- 735 EL + N++ K + LE+D N+L+ +E ++L ++ EL Sbjct: 791 ELEIYQNNIENFKNNAVDRLNVLESDLVKKRNELEQLKKEQQTHYNELNSNLTNELQELE 850 Query: 736 --LAKINHEEQSK----IQTQFGIDAKIQERDLYIENIESELSKYK----SRICRLEESI 785 K H++Q K +Q + + K E LY + + ++ K S + E Sbjct: 851 EQKKKFAHQKQQKFEELLQAKNNLSIKENELVLYAQKVNDRYNELKAIEKSNTAKSEMIN 910 Query: 786 AVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIE 845 A +E+ +++ + QE+ K ++ I E + R +L+ + ++++ E + Sbjct: 911 AKLEEFKHAEIDYLNYQNKIKQEQIKFDNQVKILESQYNQRNEILLIREEQIKQKKAEQQ 970 Query: 846 HENKELQKKNQILLEENQNL----QISLSDMQQHYNALVEKANRTDLAES--ESTKYQTQ 899 + K++QK + L EE N + + + Y + ++ + DLA+ E K + Sbjct: 971 AQEKQIQKDFKRLQEEKNNFDDQKRNKFNKISNLYLEIKKQRDEVDLAQRQIEDQKEELL 1030 Query: 900 LRDLESNLKRITHEHQTLIVQK-------------KKEIEDLE------IEFNTQIESAI 940 ++ E L++ E + +++K KK I+ +E + N + E Sbjct: 1031 IKAREGRLQKQEIEDRLAVLEKSEKRFRQEDELLAKKRIDLIERIGVLKADINKKHEILS 1090 Query: 941 RDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVE-ELNKMNLELIDKHVQKQQTQ 999 L EK +K E L+ + ++ +E N + E K+ +E DK +++ Sbjct: 1091 LRSVQLTEKAKKQQEKDADLQRKFDLLESEVERFNEEKKSEFQKLKVER-DKLAHREKNV 1149 Query: 1000 SPDYTEQYINEINKLNALLKQKDEEIIALNQKIN--NAQVSYMSMVSDY-ESKLAQFTTK 1056 S + E + + KL+ + K + +N+K+ N Q + +D ++K + T+ Sbjct: 1150 SKNMNEINL-ALAKLDLIRKNNKVDKAKINEKLALLNDQKEKIDRENDLLDAKKTEVITR 1208 Query: 1057 LENMEEEMQRVSKQLLDSKQHNEEL----QILVREQDDQIKELKETKLTFEMNIPKTEGM 1112 L ME +++ +++L + + E + Q L RE + + + L+ K +F Sbjct: 1209 LRKMENDLEFEKQKVLLDRSNIERISSDQQALARELETKYQTLEREKRSFSQRK------ 1262 Query: 1113 IISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECY 1172 + ++ + D V LK+ E+ Q R +L+++S +N ++ Sbjct: 1263 --ENELKEIDDFYQQVQHKERTLN-----LKI---EDLKQLRYLLEKESYNVNVNKKDLK 1312 Query: 1173 TKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAV--DQ 1230 +I + L + Q N +K+E LN + + S +A LRS I + Q Sbjct: 1313 VRIEHYQRLERAIKNEQHKLNNQKNNFFNKVELLNDQLNKKSSKIALLRSKIYNTYKQQQ 1372 Query: 1231 RGFEIAELWKQHLAQREADFQKTEHEL---RVQLSAFESKYEQLLDSVQSSTQEETNKIV 1287 + +I K +Q KT+ EL + Q S + + E+ L + + Q ++++ Sbjct: 1373 QQKQILLEEKHKNSQLRKSLLKTQEELHQQKAQFSIAKKQEEKKLKNQKDLIQNTLSEVI 1432 Query: 1288 TM-EQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIE 1328 +Q+T+++ ++ K+ L NL++ +I Q L+ E+E Sbjct: 1433 KQKDQITNIKQEVDLKQTQLNNLEKL---IIKQRADLQKELE 1471 Score = 123 bits (296), Expect = 5e-26 Identities = 229/1151 (19%), Positives = 491/1151 (42%), Gaps = 107/1151 (9%) Query: 494 KDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDS 553 K+ + L+ KLK +++ + ++ K + +N + +LKQ ++ D Sbjct: 385 KNNKTQRLLNKLKEDYDRLKIASLSFESMRKQSLAALNNLQDELKQKHNLLERKKHEQDG 444 Query: 554 --NKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENL--- 608 N++I L L + ++E EK N + + E+ + KK E++ L Sbjct: 445 IVNEKISELEGYRSDLVDQKLKIEREKENQERRY------KAAEASLNKKRQEIDELFLE 498 Query: 609 AETRLKAISL----LESQKFDLVQELHILQQKYDEVEDKLADISQLQS-DQVCSEIKSVH 663 A T+L SL L +QK +++ +L L+ E++ + D+ Q + DQ I+ + Sbjct: 499 ANTKLNEASLKENDLNNQKREILAKLRNLEHLKSEIDQRRRDLDQRELIDQ--QTIRKIQ 556 Query: 664 LEEQIDALSASKKELALVIENLKLDKEQ-----LYGTIKDLENDKEDIMNKLQNYI-QEN 717 L+ + + + L+IE K D+ Q IK + D E+ +N Q + Q Sbjct: 557 LDVESERADLQR---ILLIERKKNDERQQELLQYERDIKRQQTDFENTVNWEQKKLSQRE 613 Query: 718 MDLTDKLEKMSA------EKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESEL 771 +L D E++ EKI EL +IN ++SK Q ++ K++ ++ ++ L Sbjct: 614 KELKDGYEQLQLKQSEVQEKIDELNEEINRAQKSK-QNSLVLEQKLKSDLEHLNLSKNYL 672 Query: 772 SKYKSRICRLEESIAVMEDRRY---SLERKADQLGSY---LQEKQKAY----SEYTIQED 821 K + + ++S ++ED + L+R+ + L Y LQ+K+ + ++ T+Q++ Sbjct: 673 DKQQEELN--QKSDKMIEDLKVFERDLKRQKEDLSIYEKSLQQKEASLINFQNDVTVQKN 730 Query: 822 ELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQIL-LEENQNLQISLSDMQQHYNALV 880 E ++ + H + E + IE+E ++L + + + ++ +N ++ + + +L Sbjct: 731 EAYHKAQAI--HQEL-ELKKAAIENELRKLTAERKAVDADKEENTKLK-KFIDEEIRSLA 786 Query: 881 EKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAI 940 + ++ YQ + + ++N + ++ +V+K+ E+E L+ E T Sbjct: 787 NERKELEI-------YQNNIENFKNNAVDRLNVLESDLVKKRNELEQLKKEQQTHYNELN 839 Query: 941 RD-KKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQ 999 + L E E+ ++ Q + + +E NL++ EL ++ D++ + + + Sbjct: 840 SNLTNELQELEEQKKKFAHQKQQKFEELLQAKNNLSIKENELVLYAQKVNDRYNELKAIE 899 Query: 1000 SPDYTEQYINEINKLNALLKQ-KDEEIIALN--QKINNAQVSYMSMVSDYESKLAQFTTK 1056 + + + +NA L++ K EI LN KI Q+ + + V ES+ Q Sbjct: 900 KSNTAKSEM-----INAKLEEFKHAEIDYLNYQNKIKQEQIKFDNQVKILESQYNQRNEI 954 Query: 1057 LENMEEEM-QRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIIS 1115 L EE++ Q+ ++Q KQ ++ + L +E+ + + K K N+ + I Sbjct: 955 LLIREEQIKQKKAEQQAQEKQIQKDFKRL-QEEKNNFDDQKRNKFNKISNLY----LEIK 1009 Query: 1116 STIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTK- 1174 + + ++ ++Q++E I++R + E+S K + E K Sbjct: 1010 KQRDEVDLAQRQIEDQKEELLIKAREGRLQKQE--IEDRLAVLEKSEKRFRQEDELLAKK 1067 Query: 1175 ----IIQLETLNTELTG-HDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVD 1229 I ++ L ++ H++++ + QL K ++ ++ +L L S + + Sbjct: 1068 RIDLIERIGVLKADINKKHEILSLRSV-QLTEKAKKQQEKDADLQRKFDLLESEVERFNE 1126 Query: 1230 QRGFEIAELW--KQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIV 1287 ++ E +L + LA RE + K +E+ + L+ LD ++ + + + KI Sbjct: 1127 EKKSEFQKLKVERDKLAHREKNVSKNMNEINLALAK--------LDLIRKNNKVDKAKIN 1178 Query: 1288 TMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXX 1347 + + Q + D+E L L K +VI ++ + +++E EK Sbjct: 1179 EKLALLNDQKEKIDRENDL--LDAKKTEVITRLRKMENDLEFEKQKVLLDRSNIERISSD 1236 Query: 1348 XXXDLRTENQSYKQMQ-EQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELT 1406 R Y+ ++ E+ + +EN + + + K L Sbjct: 1237 QQALARELETKYQTLEREKRSFSQRKENELKEIDDFYQQVQHKERTLNLKIEDLKQLRYL 1296 Query: 1407 HQLELKDSEIYQKTHEYTITLTQR-----NDEFENVRQQLVEYEKRIE---DLTYEKESE 1458 + E + + +K + I QR +E + Q + ++E D +K S+ Sbjct: 1297 LEKESYNVNVNKKDLKVRIEHYQRLERAIKNEQHKLNNQKNNFFNKVELLNDQLNKKSSK 1356 Query: 1459 LAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVS-LNKQVAELNKALEEEVA 1517 +A+LR K++ N + QK+ +E +L + ++ L++Q A+ + A ++E Sbjct: 1357 IALLRSKIY-NTYKQQQQQKQILLEEKHKNSQLRKSLLKTQEELHQQKAQFSIAKKQEEK 1415 Query: 1518 KTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMN 1577 K + ++N E++ D+ITN++ V +++ KQ D Q + N Sbjct: 1416 KLKNQKDLIQNTLSEVIKQKDQITNIKQEVDLKQTQLNNLEKLI--IKQRADLQKELEKN 1473 Query: 1578 KELLDAVPRAE 1588 E + +AE Sbjct: 1474 SENTYRLQKAE 1484 Score = 116 bits (280), Expect = 4e-24 Identities = 243/1276 (19%), Positives = 526/1276 (41%), Gaps = 96/1276 (7%) Query: 147 LSNTIKEKDNALSVLQVKMKIMETTILDLQEKIN------EKDQIIEAKNKATTXXXXXX 200 LS KE + LQ+K ++ I +L E+IN + ++E K K+ Sbjct: 609 LSQREKELKDGYEQLQLKQSEVQEKIDELNEEINRAQKSKQNSLVLEQKLKS---DLEHL 665 Query: 201 XXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLL 260 E+ Q+ KM E+ E + K +K+ L +S + +SL + Sbjct: 666 NLSKNYLDKQQEELNQKSDKMIEDLKVFERDLKRQKEDLSIYEKSLQQKEASLINFQNDV 725 Query: 261 EAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIAN 320 + E + + QELE +++++ EE T++++ EI + Sbjct: 726 TVQKNEAYHKAQAIHQELE-LKKAAIENELRKLTAERKAVDADKEENTKLKKFIDEEIRS 784 Query: 321 MTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTAS 380 + K++E+ ++ I ++L + ES V KK + L K + T Sbjct: 785 LANERKELEIYQN---NIENFKNNAVDRLNVL--ESDLV----KKRNELEQLKKEQQTHY 835 Query: 381 KMKSPWSQLSSETLN-QDTDKKINKNEIAKLEMVIQSLNK-DLVDKEYV-----ISEKDT 433 + S L++E ++ KK + K E ++Q+ N + + E V ++++ Sbjct: 836 NELN--SNLTNELQELEEQKKKFAHQKQQKFEELLQAKNNLSIKENELVLYAQKVNDRYN 893 Query: 434 XXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEI 493 K +I +LE +H E L + N+I QEQ+K + +I Sbjct: 894 ELKAIEKSNTAKSEMI-NAKLEEFKHAEIDYLNY-------QNKIK--QEQIKFDNQVKI 943 Query: 494 KDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIK-VKSNHKLKLKQMQKTIDNFSKVSD 552 + E L EEQI Q E A K + K K + K + + F+K+S+ Sbjct: 944 LESQYNQRNEILLIREEQIKQKKAEQQAQEKQIQKDFKRLQEEKNNFDDQKRNKFNKISN 1003 Query: 553 SNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETR 612 EI + +E+ L+Q+ ++E++K L L+ GR+ + ++ ++ +E + Sbjct: 1004 LYLEIKKQRDEV-DLAQR--QIEDQKEEL---LIKAREGRLQKQEIEDRLAVLEKSEKRF 1057 Query: 613 LKAISLLESQKFDLVQELHILQQKYDEVEDKLADIS-QLQSDQVCSEIKSVHLEEQIDAL 671 + LL ++ DL++ + +L+ ++ + L+ S QL + K L+ + D L Sbjct: 1058 RQEDELLAKKRIDLIERIGVLKADINKKHEILSLRSVQLTEKAKKQQEKDADLQRKFDLL 1117 Query: 672 SAS----KKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKM 727 + +E + LK+++++L K++ + +I N +DL K K+ Sbjct: 1118 ESEVERFNEEKKSEFQKLKVERDKLAHREKNVSKNMNEI-----NLALAKLDLIRKNNKV 1172 Query: 728 SAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAV 787 KI+E LA +N +++ + +DAK E + +E++L K ++ +I Sbjct: 1173 DKAKINEKLALLNDQKEKIDRENDLLDAKKTEVITRLRKMENDLEFEKQKVLLDRSNIER 1232 Query: 788 MEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDH-DRVVE-------- 838 + + +L R+ + L+ +++++S+ E + ++ + H +R + Sbjct: 1233 ISSDQQALARELETKYQTLEREKRSFSQRKENELKEIDDFYQQVQHKERTLNLKIEDLKQ 1292 Query: 839 -KQLLEIEHENKELQKKN-QILLEENQNLQISLSDMQQHYNALVEK-ANRTDLAESESTK 895 + LLE E N + KK+ ++ +E Q L+ ++ + Q N N+ +L + K Sbjct: 1293 LRYLLEKESYNVNVNKKDLKVRIEHYQRLERAIKNEQHKLNNQKNNFFNKVELLNDQLNK 1352 Query: 896 YQTQLRDLESNL----KRITHEHQTLIVQK------KKEIEDLEIEFNTQIESAIRDKKV 945 +++ L S + K+ + Q L+ +K +K + + E + Q KK Sbjct: 1353 KSSKIALLRSKIYNTYKQQQQQKQILLEEKHKNSQLRKSLLKTQEELHQQKAQFSIAKKQ 1412 Query: 946 LNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTE 1005 +K + + + +++ + K+ I N+ V +L + L ++K + KQ+ E Sbjct: 1413 EEKKLKNQKDLIQNTLSEVIKQKDQITNIKQEV-DLKQTQLNNLEKLIIKQRADLQKELE 1471 Query: 1006 QYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQ 1065 + +L + +E+ L + + A+ +S + L K+++ +++ Sbjct: 1472 KNSENTYRLQKAERLLEEKKTKLRLEYDKAK-KVLSTAKATDQALKTKQAKVQDQFKKLV 1530 Query: 1066 RVSKQLLDSKQH-NEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDD 1124 ++K++++++ + ++ I+ +E +++ + +N+ ++ + TI P+ Sbjct: 1531 LINKKIIEARNNLLKQRNIIQKEINNRNMANFQNPYPNFLNLAPNTQVVPAQTIMPV-QT 1589 Query: 1125 ANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTE 1184 V + + ++ I ++ +L Q + L+E K +L + Sbjct: 1590 PQLVGVNYPNQPAFDFNNPLMQMQQLINQQQMLMMQK-EHQWALEEANKKNSRLAKQLKQ 1648 Query: 1185 LTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLA 1244 L H E ++ + LN +N ++++ L S ++ +R I +L + +L Sbjct: 1649 LKHHKQALTESTSEHLNYHNLLNADNSYKINSLQNLLSKVAYNTKRR---INQL-EHNLD 1704 Query: 1245 QREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEE 1304 AD + HEL QLLD +++ T + S +L+ + Sbjct: 1705 PETADLNQL-HELNAN--------SQLLDEIRTVLSNTTTNTNAVVPANSYSKELRMLFD 1755 Query: 1305 HLRNLQEKYADVIN-QIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQ 1363 ++ +K A + N Q E+ ++I A + +++ Sbjct: 1756 EIKADFKKQAVLFNTQKEVFTNQINQLAQAVEQGPIEVRKTLESQDQKYQQMFDNFRDAY 1815 Query: 1364 EQSILNINEENAQLKK 1379 EQ+I + EN +++K Sbjct: 1816 EQNISLLRNENNEVQK 1831 Score = 105 bits (252), Expect = 1e-20 Identities = 236/1186 (19%), Positives = 503/1186 (42%), Gaps = 127/1186 (10%) Query: 453 QLEHQQHMEGPSLIHVGTNTEDVNEI-AKVQEQLKQELND----EIKDVNVKDL-IEKLK 506 Q E Q++ + + ++ V+ + + +E+LK+E++D K + K L + L Sbjct: 218 QSERLQNLIDERIAKLNNDSYGVSSLDSSTRERLKKEIHDLSEQRKKLQSAKKLHLYNLN 277 Query: 507 SAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHH 566 +E I + +++ +++ ++++ H KLK + +DN + K+ + Sbjct: 278 LKKESIRRYRSQLEQYLESLKQMRNEHNKKLKGYAQNLDNIKNEVEKAKQ---------N 328 Query: 567 LSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDL 626 + + ++ + K N + + IE+EN + AI Sbjct: 329 FNDQQLKILQSKANADQYFA-------------LRKIELENSYKKAKNAILEANKAHAKN 375 Query: 627 VQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLK 686 VQE L K ++ + L ++L+ D +I S+ E S K+ LA + NL+ Sbjct: 376 VQEEQALANKNNKTQRLL---NKLKEDYDRLKIASLSFE------SMRKQSLA-ALNNLQ 425 Query: 687 LDKEQLYGTIKDLENDKEDIMN-KLQNYIQENMDLTDKLEKMSAEKISE------LLAKI 739 + +Q + ++ +++++ I+N K+ DL D+ K+ EK ++ A + Sbjct: 426 DELKQKHNLLERKKHEQDGIVNEKISELEGYRSDLVDQKLKIEREKENQERRYKAAEASL 485 Query: 740 NHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKA 799 N + Q + + K+ E L ++ ++ + +++ LE + ++ RR L+++ Sbjct: 486 NKKRQEIDELFLEANTKLNEASLKENDLNNQKREILAKLRNLEHLKSEIDQRRRDLDQRE 545 Query: 800 ---DQLGSYLQ---EKQKAYSE--YTIQEDELVNRLAVLMDHDRVVEKQLLEIEH----E 847 Q +Q E ++A + I+ + R L+ ++R +++Q + E+ E Sbjct: 546 LIDQQTIRKIQLDVESERADLQRILLIERKKNDERQQELLQYERDIKRQQTDFENTVNWE 605 Query: 848 NKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLR-DLES- 905 K+L ++ + L + + LQ+ S++Q+ + L E+ NR ++ S + +L+ DLE Sbjct: 606 QKKLSQREKELKDGYEQLQLKQSEVQEKIDELNEEINRAQKSKQNSLVLEQKLKSDLEHL 665 Query: 906 NLKR--ITHEHQTLIVQKKKEIEDLEI---EFNTQIESAIRDKKVLNEKYEKNIEYVTQL 960 NL + + + + L + K IEDL++ + Q E +K L +K I + + Sbjct: 666 NLSKNYLDKQQEELNQKSDKMIEDLKVFERDLKRQKEDLSIYEKSLQQKEASLINFQNDV 725 Query: 961 EAQLQEYKNNIENLNMNVE--------ELNKMNLELIDKHVQKQQTQSPDYTEQYINEIN 1012 Q E + + ++ +E EL K+ E K++ +++I+E Sbjct: 726 TVQKNEAYHKAQAIHQELELKKAAIENELRKLTAERKAVDADKEENTK---LKKFIDE-- 780 Query: 1013 KLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLL 1072 ++ +L ++ E I N I N + + + ++ ES L + +LE +++E Q + L Sbjct: 781 EIRSLANERKELEIYQN-NIENFKNNAVDRLNVLESDLVKKRNELEQLKKEQQTHYNE-L 838 Query: 1073 DSKQHNE--ELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDX 1130 +S NE EL+ ++ Q ++ E L + N+ E ++ + ++D N + Sbjct: 839 NSNLTNELQELEEQKKKFAHQKQQKFEELLQAKNNLSIKENELVLYA-QKVNDRYNELKA 897 Query: 1131 XXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDV 1190 + + EE E L Q+ K+ E + ++ LE+ + + Sbjct: 898 IEKSNTAKSEMINAKLEEFKHAEIDYLNYQN-KIKQEQIKFDNQVKILESQYNQRNEILL 956 Query: 1191 VNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELW----KQH---- 1242 + +EQI Q K++ + + + E +++ + +I+ L+ KQ Sbjct: 957 IREEQIKQKKAEQQAQEKQIQKDFKRLQEEKNNFDDQKRNKFNKISNLYLEIKKQRDEVD 1016 Query: 1243 LAQREADFQKTE-----HELRVQLSAFESKYEQLLDSVQSSTQEE----TNKIVTMEQVT 1293 LAQR+ + QK E E R+Q E + L S + QE+ +I +E++ Sbjct: 1017 LAQRQIEDQKEELLIKAREGRLQKQEIEDRLAVLEKSEKRFRQEDELLAKKRIDLIERIG 1076 Query: 1294 SLQNKLQDKEEHL-----------RNLQEKYADVINQIEILRSEI----EDEKVAFXXXX 1338 L+ + K E L + QEK AD+ + ++L SE+ E++K F Sbjct: 1077 VLKADINKKHEILSLRSVQLTEKAKKQQEKDADLQRKFDLLESEVERFNEEKKSEFQKLK 1136 Query: 1339 XXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLK-KSSXXXXXXXXXXXXRVND 1397 + N+ + + ++ N + + K R ND Sbjct: 1137 VERDKLAHREKNVSKNMNEINLALAKLDLIRKNNKVDKAKINEKLALLNDQKEKIDREND 1196 Query: 1398 -AEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLV--EYEKRIEDLTYE 1454 +AK E+ +L ++++ + + + L + N E + QQ + E E + + L E Sbjct: 1197 LLDAKKTEVITRLRKMENDL--EFEKQKVLLDRSNIERISSDQQALARELETKYQTLERE 1254 Query: 1455 KESELAILRLKMHENANHYETMQKESEIERVKLIEELNVK-ITESVSLNKQVAELNKALE 1513 K S ++ E + Y+ +Q + +K+ + ++ + E S N V + K L+ Sbjct: 1255 KRSFSQRKENELKEIDDFYQQVQHKERTLNLKIEDLKQLRYLLEKESYNVNVNK--KDLK 1312 Query: 1514 EEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVS 1559 + ++ A++N++ + LN++ N N V + ++ K S Sbjct: 1313 VRIEHYQRLERAIKNEQHK---LNNQKNNFFNKVELLNDQLNKKSS 1355 Score = 97.9 bits (233), Expect = 2e-18 Identities = 168/933 (18%), Positives = 381/933 (40%), Gaps = 63/933 (6%) Query: 669 DALSASKKELALVIENLKLDKEQLY-GTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKM 727 D + +E + + KLDK G D+ + + K + +++D + + Sbjct: 37 DGYIKANQENLIANQYKKLDKNSYQNGNNSFYTKDELEKLKKQSFQVNQDIDYYQQAQTE 96 Query: 728 SAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEE---- 783 + + LL I+ E + Q QF + ER I +EL + S + +E+ Sbjct: 97 ISSERQRLLQAIDDLEAN--QDQFHPEDFQAERQYLI----NELDRLDSELYHIEQYKND 150 Query: 784 SIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAV-LMDHDRVVEKQLL 842 SI + + L + ++ SY K + IQ D+L N+LA +++ ++ + Sbjct: 151 SIDFVNELNQRLSAEQAKIDSYNSSLDKNIRKDYIQIDQLKNKLAEETTEYNDLLNRSTD 210 Query: 843 EIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRD 902 EI +++ ++ ++ E L Y + L S + + ++ D Sbjct: 211 EISEIDRQSERLQNLIDERIAKLN------NDSYGV-------SSLDSSTRERLKKEIHD 257 Query: 903 LESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEA 962 L K++ + + + E + + +Q+E + K + ++ K ++ Q Sbjct: 258 LSEQRKKLQSAKKLHLYNLNLKKESIR-RYRSQLEQYLESLKQMRNEHNKKLKGYAQ--- 313 Query: 963 QLQEYKNNIENL--NMNVEELNKMNLEL-IDKHVQKQQTQSPDYTEQYINEINKLNALLK 1019 L KN +E N N ++L + + D++ ++ + + ++ N I + N Sbjct: 314 NLDNIKNEVEKAKQNFNDQQLKILQSKANADQYFALRKIELENSYKKAKNAILEANKAHA 373 Query: 1020 QKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDS-KQHN 1078 + +E AL K N Q + DY+ +L + E+M ++ L D KQ + Sbjct: 374 KNVQEEQALANKNNKTQRLLNKLKEDYD-RLKIASLSFESMRKQSLAALNNLQDELKQKH 432 Query: 1079 EELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXX 1138 L+ EQD + E K++ E+ +++ ++ ++ + + N + Sbjct: 433 NLLERKKHEQDGIVNE----KIS-ELEGYRSD--LVDQKLK-IEREKENQERRYKAAEAS 484 Query: 1139 XXXLKVQEEEEFIQERSVLQEQSAK---LNTELQECYTKIIQLETLNTELTGH--DVVNQ 1193 + + +E F++ + L E S K LN + +E K+ LE L +E+ D+ + Sbjct: 485 LNKKRQEIDELFLEANTKLNEASLKENDLNNQKREILAKLRNLEHLKSEIDQRRRDLDQR 544 Query: 1194 EQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKT 1253 E I+Q + QL+ E++ + + + D+R E+ + +++ + +++ DF+ T Sbjct: 545 ELIDQQTIRKIQLDVESER--ADLQRILLIERKKNDERQQELLQ-YERDIKRQQTDFENT 601 Query: 1254 EHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKY 1313 + + +LS E + + + +Q E KI +++ N+ Q +++ L++K Sbjct: 602 VNWEQKKLSQREKELKDGYEQLQLKQSEVQEKI---DELNEEINRAQKSKQNSLVLEQKL 658 Query: 1314 ADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYK------QMQEQSI 1367 + + + ++ ++ ++ DL+ + + Q +E S+ Sbjct: 659 KSDLEHLNLSKNYLDKQQEELNQKSDKMIEDLKVFERDLKRQKEDLSIYEKSLQQKEASL 718 Query: 1368 LNI-NEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTIT 1426 +N N+ Q ++ + E ++ +LT + + D++ + T + Sbjct: 719 INFQNDVTVQKNEAYHKAQAIHQELELKKAAIENELRKLTAERKAVDADKEENT-KLKKF 777 Query: 1427 LTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVK 1486 + + N R++L Y+ IE+ L +L + + N E ++KE + + Sbjct: 778 IDEEIRSLANERKELEIYQNNIENFKNNAVDRLNVLESDLVKKRNELEQLKKEQQTHYNE 837 Query: 1487 LIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIV-TLNDEITNLQN 1545 L L ++ E K+ A + EE+ + + EN+ + +ND L+ Sbjct: 838 LNSNLTNELQELEEQKKKFAHQKQQKFEELLQAKNNLSIKENELVLYAQKVNDRYNELKA 897 Query: 1546 MVRASSSKIQKHVSFASDTKQGRDEQLDNTMNK 1578 + +++++K + + + K + L N NK Sbjct: 898 IEKSNTAKSEMINAKLEEFKHAEIDYL-NYQNK 929 Score = 36.3 bits (80), Expect = 7.0 Identities = 56/256 (21%), Positives = 124/256 (48%), Gaps = 34/256 (13%) Query: 484 QLKQELNDEIKDVN-VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQK 542 QL+ L+ E D+N + +L + +E T L++ N N + +++ +L+ + Sbjct: 1698 QLEHNLDPETADLNQLHELNANSQLLDEIRTVLSNT--TTNTNAVVPANSYSKELRMLFD 1755 Query: 543 TID-NFSKVS---DSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDV 598 I +F K + ++ KE+ T +++ L+Q V E+G +++ + +ES Sbjct: 1756 EIKADFKKQAVLFNTQKEV--FTNQINQLAQAV-----EQGPIEVR-------KTLESQD 1801 Query: 599 YKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSE 658 K +N + + ISLL ++ ++ ++L L YDE+ + +++ + E Sbjct: 1802 QKYQQMFDNFRDAYEQNISLLRNENNEVQKKLTDL---YDEIAAIKTNTEKIKKTTLRPE 1858 Query: 659 IKSVHLE--EQIDALSASKKELA----LVIENLKLDKEQLYGTIKDLENDKEDIMNKLQN 712 +++ E ++++ KK+ V +NL++D Q +DL + K++ +N+L N Sbjct: 1859 VRNNANEGLASFNSVNRDKKDYLDQTLPVHQNLRIDLNQN----RDLSHAKKERINQLAN 1914 Query: 713 YIQENMDLTDKLEKMS 728 I+ +L +K ++ S Sbjct: 1915 EIKTIKELIEKRKQTS 1930 >UniRef50_Q16IF0 Cluster: Condensin, SMC5-subunit, putative; n=1; Aedes aegypti|Rep: Condensin, SMC5-subunit, putative - Aedes aegypti (Yellowfever mosquito) Length = 1237 Score = 126 bits (305), Expect = 4e-27 Identities = 249/1165 (21%), Positives = 497/1165 (42%), Gaps = 137/1165 (11%) Query: 498 VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEI 557 + DL +KL AE I Q + ++ + + +K + + ++ ++ + + K D + Sbjct: 10 IADLEKKLLKAE--ILQRDQKLHLSEE----LKHSLEDEISKLHERVAEAEKNLDFKESS 63 Query: 558 VRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAIS 617 ++E+ L +K+A LE+ L + L D+ ++ K+ ++++N A Sbjct: 64 FNISEQC--LKEKIAYLEDRIEVLGVELTAKDA------ELEKQYLDLKN-------AEG 108 Query: 618 LLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSE--IKSVHLEEQIDALSASK 675 L+ ++ +V++ +++ E++ L DI Q + E +K+V LEE+ A+ K Sbjct: 109 QLDEEESLVVEKERQIEKLTGEIQGLLNDIRQRDVKLLEGETGLKAV-LEEKDGAIGKLK 167 Query: 676 KELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKM--SAEKIS 733 KEL E L++ +E + K D+E + +L I N ++ KLE A+K+ Sbjct: 168 KEL----EELRMKEE----SAKVAVEDRERKLGELNVRIVSNEEIIKKLEDSLKDAKKVE 219 Query: 734 ELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESE--LSKYKSRICRLEESIAVMEDR 791 + L + ++ ++ + + AKIQ+ DL + SE + +S+ LE+ +E + Sbjct: 220 QTLEEAIKAKEKSLEEKESLLAKIQD-DLKNSSAGSEQQMVLLRSKESELEQKQHEVEAK 278 Query: 792 RYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKEL 851 ++ + + + ++ ++A + +E L + A L + E L ++ + E Sbjct: 279 QFQISNLESTITNLTKKLEEAVKD---REARLAEQRASLEFETKSKEDLLNKLANYETEQ 335 Query: 852 QKKNQILLEENQ----NLQISLSDMQQHYNALVEKANRTD--LAESEST--KYQTQLRDL 903 K++ LLE+N +LQ L D++ ++V++ T A+ +S K + L Sbjct: 336 LAKDK-LLEDNDVLISSLQTKLKDLEVAKASVVQELEDTTKRFADRDSALRKLNEERMHL 394 Query: 904 ESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQ 963 L++ E + I ++ +++ + + A K+ + V++LEA Sbjct: 395 SEQLEKTRKESASAIALLEERLKNAQKLHEEDVRKA---KEAQKDTLASKDAIVSELEAS 451 Query: 964 LQEYKNNIENLNMNVEELNKMNLEL-IDKHVQKQQTQSPDYTEQY--INE-INKLNALLK 1019 L + + L ++ E +K+N ++K ++ Q TE +N+ + N L+ Sbjct: 452 LDKLRQEKTELLLHDELTSKLNENRELNKQIESLTAQLATKTENLDKLNQSLTGTNGKLE 511 Query: 1020 QKDEEIIALNQKINNAQVSYMSM---VSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQ 1076 + ++I L + ++ Y + + E K Q + +++E+E+ + LDS Sbjct: 512 ATEAKLIELQEAFGKLEIEYADLKRKLEAQEQKSTQLQQQKQDLEKEIDTLRSSTLDS-- 569 Query: 1077 HNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXX 1136 N EL + E + K+L+E + F N K + +E D+AN + Sbjct: 570 -NSELSKVTDELKTKQKQLEELQDAF--NGSKID-------MERRLDEANQTNQGLNEQI 619 Query: 1137 XXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECY-TKIIQLETLNTELTGHDVVNQEQ 1195 +V+ E + + + + +E +LN EL + T I+ E L E+ G +E+ Sbjct: 620 D-----RVRNEMQQVSSQKIDREN--ELNVELAKIKETAEIERENLVQEIAGLKASFEEE 672 Query: 1196 INQLK----SKLEQLNTENDNLLSTVAELRSSISS-----------AVDQRGFEIAELWK 1240 NQL +K E+ T + L V L S+S AV +R E AE Sbjct: 673 RNQLVKGGVAKSEEFETVKEELSGKVKSLEKSLSELERELAKNRECAVKER--EEAEGRL 730 Query: 1241 QHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTME-QVTSLQNKL 1299 + ++E QK EL+ + S+ + E L S++ + + ++++ +++ L+ +L Sbjct: 731 KEQMEKETTLQKEFDELKKEESSLRAALEDLRQSMEKGSHDASSQLDAKNTKISELEKEL 790 Query: 1300 QDKEEHLRNLQEKYADVINQIEILRSEIED------EKVAFXXXXXXXXXXXXXXXXDLR 1353 + +E L QE+ D Q+E D + + ++ Sbjct: 791 RSVQEELSRKQEQVDDSTKQLERNAETHSDLLKQLEQNLNQIQELSGDKAKAEGSLKEIS 850 Query: 1354 TENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXR--VNDAEAKVLELTHQLEL 1411 E S+K ++ + EE LK+ + V + ++ V EL +LE Sbjct: 851 DELASFKAKYDE----MEEEQVDLKQLNEIERLHKEVKEKESYVFEKDSSVAELRKKLEQ 906 Query: 1412 KDSEIYQ--KTHEYTIT-LTQRNDEFENVRQQLVEYEKRIE----------DLTYEKESE 1458 K E Q K EYT LT+++ + E E ++ +E D E+ Sbjct: 907 KQEETQQLMKKLEYTEKCLTEKSQQEEKTAATSSELKEALEKSKAAVKEQDDKIKEQGRT 966 Query: 1459 LAILRLKMHENANHYETM---QKESEIE--------RVKLIEELNVKITESVSLNKQVAE 1507 + L K+ + +E + +K SE E KL+E NVK E L+ ++AE Sbjct: 967 INELETKLSAQSTQFEELLNKKKASETESSHKLHEMNQKLLELENVKQQEISDLSAKLAE 1026 Query: 1508 LNKALE---EEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDT 1564 E E AKT ++E ++ E+ E+ + ++ ++ K+QK V Sbjct: 1027 TMNRFETQMAESAKTVGSMRSVEKRQYELECEKKEMELRETEMQITTRKLQKEVDLLRSQ 1086 Query: 1565 KQGRDEQLDNTMNKELLDAVPRAEL 1589 +D ++ + +EL +A A L Sbjct: 1087 LLLKDSEV-RKLTQELANAPTSAPL 1110 Score = 124 bits (299), Expect = 2e-26 Identities = 213/1012 (21%), Positives = 426/1012 (42%), Gaps = 76/1012 (7%) Query: 483 EQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQK 542 E+L E+ + D+ +D+ KL E + + +E D A + K ++K + + Sbjct: 125 EKLTGEIQGLLNDIRQRDV--KLLEGETGLKAVLEEKDGAIGKLKKELEELRMKEESAKV 182 Query: 543 TI-DNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSG-RMIESDVYK 600 + D K+ + N IV E + L + + ++ + L+ + + ES + K Sbjct: 183 AVEDRERKLGELNVRIVSNEEIIKKLEDSLKDAKKVEQTLEEAIKAKEKSLEEKESLLAK 242 Query: 601 KMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIK 660 +++N + + + LL S++ +L Q+ H EVE K IS L+S + + K Sbjct: 243 IQDDLKNSSAGSEQQMVLLRSKESELEQKQH-------EVEAKQFQISNLEST-ITNLTK 294 Query: 661 SVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDL 720 LEE + +E L + L+ E KED++NKL NY E + Sbjct: 295 K--LEEAV-----KDREARLAEQRASLEFET---------KSKEDLLNKLANYETEQL-A 337 Query: 721 TDKLEKMSAEKISELLAKINHEEQSK---IQTQFGIDAKIQERDLYIENIESELSKYKSR 777 DKL + + IS L K+ E +K +Q + +RD + + E + Sbjct: 338 KDKLLEDNDVLISSLQTKLKDLEVAKASVVQELEDTTKRFADRDSALRKLNEERMHLSEQ 397 Query: 778 ICRLEE----SIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDH 833 + + + +IA++E+R + ++ ++ +E QK + +D +V+ L +D Sbjct: 398 LEKTRKESASAIALLEERLKNAQKLHEEDVRKAKEAQK---DTLASKDAIVSELEASLDK 454 Query: 834 DRVVEKQLL---EIE---HENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTD 887 R + +LL E+ +EN+EL K+ + L + +L + Q K T+ Sbjct: 455 LRQEKTELLLHDELTSKLNENRELNKQIESLTAQLATKTENLDKLNQSLTGTNGKLEATE 514 Query: 888 LAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLN 947 E + +L ++LKR + Q +++ +DLE E +T S + L+ Sbjct: 515 AKLIELQEAFGKLEIEYADLKRKLEAQEQKSTQLQQQKQDLEKEIDTLRSSTLDSNSELS 574 Query: 948 EKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQY 1007 + ++ QLE + + ++ ++E N+ N + +++ + + + + + Q Sbjct: 575 KVTDELKTKQKQLEELQDAFNGSKIDMERRLDEANQTN-QGLNEQIDRVRNEMQQVSSQK 633 Query: 1008 INEINKLN---ALLKQKDE-EIIALNQKINNAQVSY----MSMVSDYESKLAQFTTKLEN 1059 I+ N+LN A +K+ E E L Q+I + S+ +V +K +F T E Sbjct: 634 IDRENELNVELAKIKETAEIERENLVQEIAGLKASFEEERNQLVKGGVAKSEEFETVKEE 693 Query: 1060 MEEEMQRVSKQLLDSKQH---NEELQILVREQ-DDQIKEL--KETKLTFEMNIPKTEGMI 1113 + +++ + K L + ++ N E + RE+ + ++KE KET L E + K E Sbjct: 694 LSGKVKSLEKSLSELERELAKNRECAVKEREEAEGRLKEQMEKETTLQKEFDELKKEESS 753 Query: 1114 ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYT 1173 + + +E + K+ E E+ + RSV QE+ ++ ++ + Sbjct: 754 LRAALEDLRQSMEK-GSHDASSQLDAKNTKISELEK--ELRSV-QEELSRKQEQVDDSTK 809 Query: 1174 KIIQLETLNTELTGHDVVNQEQINQL---KSKLE-QLNTENDNLLSTVAELRSSISSAVD 1229 ++ + +++L N QI +L K+K E L +D L S A+ VD Sbjct: 810 QLERNAETHSDLLKQLEQNLNQIQELSGDKAKAEGSLKEISDELASFKAKYDEMEEEQVD 869 Query: 1230 QRGF-EIAELWKQHLAQREADFQKTEH--ELRVQLSAFESKYEQLLDSVQSSTQEETNKI 1286 + EI L K+ + F+K ELR +L + + +QL+ ++ + + T K Sbjct: 870 LKQLNEIERLHKEVKEKESYVFEKDSSVAELRKKLEQKQEETQQLMKKLEYTEKCLTEKS 929 Query: 1287 VTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQ----IEILRSEIEDEKVAFXXXXXXXX 1342 E+ + ++L++ E + ++ D I + I L +++ + F Sbjct: 930 QQEEKTAATSSELKEALEKSKAAVKEQDDKIKEQGRTINELETKLSAQSTQFEELLNKKK 989 Query: 1343 XXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKV 1402 L NQ +++ I++ +A+L ++ V + V Sbjct: 990 ASETESSHKLHEMNQKLLELENVKQQEISDLSAKLAETMNRFETQMAESAKTVGSMRS-V 1048 Query: 1403 LELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYE 1454 + ++LE + E+ + E IT + E + +R QL+ + + LT E Sbjct: 1049 EKRQYELECEKKEMELRETEMQITTRKLQKEVDLLRSQLLLKDSEVRKLTQE 1100 Score = 108 bits (259), Expect = 1e-21 Identities = 203/1003 (20%), Positives = 436/1003 (43%), Gaps = 112/1003 (11%) Query: 90 ISESLANTLKQKEILMEKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSN 149 + +SL + K ++ L E IK KE S +++ Q+ + + Sbjct: 208 LEDSLKDAKKVEQTLEEAIKA-KEKSLEEKESLLAKIQDDLKNSSAGSEQQMVLLRSKES 266 Query: 150 TIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXX 209 +++K + + Q ++ +E+TI +L +K+ E + EA+ Sbjct: 267 ELEQKQHEVEAKQFQISNLESTITNLTKKLEEAVKDREAR------------------LA 308 Query: 210 XXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISL 269 + + TK +E+ + A ++ E+ K +E DV ISSL+ K LE A+ Sbjct: 309 EQRASLEFETKSKEDLLNKLANYETEQLAKDKLLEDNDVLISSLQTKLKDLEVAK----- 363 Query: 270 EHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIE 329 + + QELE L ++ + S E+ + ++ + IA + E K + Sbjct: 364 --ASVVQELEDTTKRFADRDSALRKLNEERMHLS-EQLEKTRKESASAIALLEERLKNAQ 420 Query: 330 LLEHLNC-QIRQTNKE-LENKLATMGTESKAVSSPSKKGSPLI-------SRKSGRNTAS 380 L + + ++ K+ L +K A + ++ ++ + L+ R Sbjct: 421 KLHEEDVRKAKEAQKDTLASKDAIVSELEASLDKLRQEKTELLLHDELTSKLNENRELNK 480 Query: 381 KMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXX 440 +++S +QL+++T N D K+N++ + +++ L++ + + + Sbjct: 481 QIESLTAQLATKTENLD---KLNQS-LTGTNGKLEATEAKLIELQEAFGKLEIEYADLKR 536 Query: 441 XXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVN-EIAKVQEQL--KQELNDEIKDV- 496 ++ QLQ + +Q +E + + ++T D N E++KV ++L KQ+ +E++D Sbjct: 537 KLEAQEQKSTQLQ-QQKQDLE-KEIDTLRSSTLDSNSELSKVTDELKTKQKQLEELQDAF 594 Query: 497 --NVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSN 554 + D+ +L A + LN++ID M +V S + ++ + + ++ Sbjct: 595 NGSKIDMERRLDEANQTNQGLNEQIDRVRNEMQQVSSQKIDRENELNVELAKIKETAEIE 654 Query: 555 KEIVRLTEELHHLSQKVAELEEEKGNL---------QLHLVDYDSGRMIESDVYKKMIEM 605 +E L +E+ L A EEE+ L + V + ++S + K + E+ Sbjct: 655 RE--NLVQEIAGLK---ASFEEERNQLVKGGVAKSEEFETVKEELSGKVKS-LEKSLSEL 708 Query: 606 E-NLAETRLKAISLLESQKFDLVQELH---ILQQKYDEVEDKLADISQLQSDQVCSEIKS 661 E LA+ R A+ E + L +++ LQ+++DE++ + + + D S K Sbjct: 709 ERELAKNRECAVKEREEAEGRLKEQMEKETTLQKEFDELKKEESSLRAALEDLRQSMEKG 768 Query: 662 VH-LEEQIDA----LSASKKELALVIENLKLDKEQLYGTIKDLENDKE---DIMNKLQNY 713 H Q+DA +S +KEL V E L +EQ+ + K LE + E D++ +L+ Sbjct: 769 SHDASSQLDAKNTKISELEKELRSVQEELSRKQEQVDDSTKQLERNAETHSDLLKQLEQN 828 Query: 714 IQENMDLT-DKLE-KMSAEKISELLA--KINHEEQSKIQTQFGIDAKIQERDLYIENIES 769 + + +L+ DK + + S ++IS+ LA K ++E + Q +D K IE + Sbjct: 829 LNQIQELSGDKAKAEGSLKEISDELASFKAKYDEMEEEQ----VDLKQLNE---IERLHK 881 Query: 770 ELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAV 829 E+ + +S + + S+A + + + + QL L+ +K +E + QE++ A Sbjct: 882 EVKEKESYVFEKDSSVAELRKKLEQKQEETQQLMKKLEYTEKCLTEKSQQEEKTA---AT 938 Query: 830 LMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTD-- 887 + +EK ++ ++ +++++ + + E L + ++ N +KA+ T+ Sbjct: 939 SSELKEALEKSKAAVKEQDDKIKEQGRTINELETKLSAQSTQFEELLNK--KKASETESS 996 Query: 888 ---------LAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIES 938 L E E+ K Q ++ DL + L + +T + + K + + Q E Sbjct: 997 HKLHEMNQKLLELENVK-QQEISDLSAKLAETMNRFETQMAESAKTVGSMRSVEKRQYEL 1055 Query: 939 AIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIEN-LNMNVEELNKMNLELIDKHVQKQQ 997 K++ E E ++ T+ +LQ+ + + + L + E+ K+ EL + Sbjct: 1056 ECEKKEM--ELRETEMQITTR---KLQKEVDLLRSQLLLKDSEVRKLTQELANAPTSAPL 1110 Query: 998 TQSPDY---TEQYINEINKLNALLKQKDEEIIALNQKINNAQV 1037 S + TE I+ +N + A +++K++++ Q + + Sbjct: 1111 ISSAEANGDTEAQISFLNSIIADMQRKNDKLTLRIQALEQTSI 1153 Score = 70.1 bits (164), Expect = 5e-10 Identities = 130/677 (19%), Positives = 284/677 (41%), Gaps = 78/677 (11%) Query: 922 KKEIEDLEIEFNTQIESAIRDKKV-LNEKYEKNIE-YVTQLEAQLQEYKNNIE--NLNMN 977 K+ I DLE + + E RD+K+ L+E+ + ++E +++L ++ E + N++ + N Sbjct: 7 KERIADLEKKL-LKAEILQRDQKLHLSEELKHSLEDEISKLHERVAEAEKNLDFKESSFN 65 Query: 978 V-EELNKMNLELIDKHVQ----KQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKI 1032 + E+ K + ++ ++ + + + +QY+ ++ L +++ ++ ++I Sbjct: 66 ISEQCLKEKIAYLEDRIEVLGVELTAKDAELEKQYL-DLKNAEGQLDEEESLVVEKERQI 124 Query: 1033 NNAQVSYMSMVSDYES---KLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQD 1089 +++D KL + T L+ + EE +L K+ EEL++ +E+ Sbjct: 125 EKLTGEIQGLLNDIRQRDVKLLEGETGLKAVLEEKDGAIGKL---KKELEELRM--KEES 179 Query: 1090 DQIK-ELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEE 1148 ++ E +E KL E+N+ I +E DA V+ ++ +E Sbjct: 180 AKVAVEDRERKLG-ELNVRIVSNEEIIKKLEDSLKDAKKVEQTLEEA--------IKAKE 230 Query: 1149 EFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNT 1208 + ++E+ L AK+ +L+ Q L + ++ Q + ++E Sbjct: 231 KSLEEKESLL---AKIQDDLKNSSAGSEQQMVLLRS-------KESELEQKQHEVEAKQF 280 Query: 1209 ENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQ-KTEHELRVQLSAFESK 1267 + NL ST+ L + AV R +AE + +F+ K++ +L +L+ +E+ Sbjct: 281 QISNLESTITNLTKKLEEAVKDREARLAE------QRASLEFETKSKEDLLNKLANYET- 333 Query: 1268 YEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRS-- 1325 EQL E N ++ ++SLQ KL+D E ++ ++ D + S Sbjct: 334 -EQLA----KDKLLEDNDVL----ISSLQTKLKDLEVAKASVVQELEDTTKRFADRDSAL 384 Query: 1326 -EIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXX 1384 ++ +E++ L ++ +++ E+ + E S Sbjct: 385 RKLNEERMHLSEQLEKTRKESASAIALLEERLKNAQKLHEEDVRKAKEAQKDTLASKDAI 444 Query: 1385 XXXXXXXXXRVNDAEAKVL---ELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQL 1441 ++ + ++L ELT +L ++ E+ ++ T L + + + + Q L Sbjct: 445 VSELEASLDKLRQEKTELLLHDELTSKLN-ENRELNKQIESLTAQLATKTENLDKLNQSL 503 Query: 1442 VEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSL 1501 ++E +E ++ L+ E K EIE L +L + +S L Sbjct: 504 TGTNGKLE------ATEAKLIELQ--------EAFGK-LEIEYADLKRKLEAQEQKSTQL 548 Query: 1502 NKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFA 1561 +Q +L K ++ + T + + L E+ T ++ LQ+ S +++ + A Sbjct: 549 QQQKQDLEKEIDTLRSSTLDSNSELSKVTDELKTKQKQLEELQDAFNGSKIDMERRLDEA 608 Query: 1562 SDTKQGRDEQLDNTMNK 1578 + T QG +EQ+D N+ Sbjct: 609 NQTNQGLNEQIDRVRNE 625 >UniRef50_A0E6F4 Cluster: Chromosome undetermined scaffold_8, whole genome shotgun sequence; n=2; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_8, whole genome shotgun sequence - Paramecium tetraurelia Length = 1391 Score = 126 bits (305), Expect = 4e-27 Identities = 221/1146 (19%), Positives = 489/1146 (42%), Gaps = 112/1146 (9%) Query: 474 DVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNH 533 D+ + Q + KQ+L E+K + +++ + +Q +I ++ + S++ Sbjct: 130 DLQQQINEQNKYKQKLEAELKFYKDNRFTQTIETQDMNFSQNQRKIKEMEDDIQILISDY 189 Query: 534 KLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRM 593 ++++K ++ + S +I ++ ++ LS ++ ++ NL++ ++ ++ Sbjct: 190 SRNQEKLEKALNE--QKQQSKYDIDQMKSQIQSLSSQIQGWQQRYQNLEIMKIELEN--- 244 Query: 594 IESDVYKKMIEMENLAETRLKAISLLESQ-KFDLVQELHI-LQQKYDEVEDKLADISQLQ 651 K+I +E + + S ESQ D V +L + Q++ ++ D A+I Q Q Sbjct: 245 -------KLIILEKENQQLIGKSSYRESQANLDTVSQLKDQIYQQFKQINDLKAEIQQKQ 297 Query: 652 SDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKE--QLYGTIKDLENDKEDIMNK 709 + + +L+++++ S S+ + +EN + E +L I+ L+ + E+ + Sbjct: 298 QSEYQLIKEQQNLKQKLEQ-SQSQTYNSQQVENTQYVNEIFKLKQYIEQLQYENENYRTQ 356 Query: 710 LQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQS--KIQTQFGIDAKIQERDLYIENI 767 N Q +++ K E ++I+ L +I + + +QTQ+ QE IE + Sbjct: 357 KSNLYQNQTNISSK-EVQQNQQINAYLEEIERLKGNIFSLQTQYEKQLNDQENRFQIE-L 414 Query: 768 ESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEK---QKAYSEYTIQEDELV 824 +S K+ S+ L + E+ R++ + + + +Q K K Y + T+ ED L+ Sbjct: 415 KSVSDKFVSQQKELNCKTQIFEESRFTFQNQQQIQENDIQTKIWQDKFYEQQTLNED-LM 473 Query: 825 NRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEK-- 882 + L + + E++ K +Q + L+EE QN+ SL + HY + + Sbjct: 474 YKHQELRNQLTQYLNYKTQNEYDQKTIQNL-EALVEEQQNIMHSLYQKELHYKDTINQYM 532 Query: 883 --------------ANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDL 928 N+ + + + Q +LRD ES L + ++++ E+E L Sbjct: 533 LIIEEHQQRNNGVFENQIQQLQLQLDQLQIKLRDQESQLN--IKSSKCFDLERQIEVEKL 590 Query: 929 EI-EFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVE-ELNKMNL 986 E + ++ +K+ ++ E ++ + + A + +N + + VE + ++ + Sbjct: 591 RFSERESLFSQQLKQEKIRIQQLELQVDNLQKDMALQNQKRNEVIKEYIYVENQQDQERI 650 Query: 987 ELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDE---------EIIALNQKINNAQV 1037 L+++ +Q Q + EQYI N+ NA + Q ++ +I L +++ + Sbjct: 651 ILLEQSLQNLQQEYLLMKEQYICVQNQYNAQIIQIEQLQGLQEDKSKIRQLEEQLRMLKD 710 Query: 1038 SYMSMVSDYESKLAQFTTK------------LENMEEEMQRVSKQ--LLDSKQHNEELQI 1083 Y + + + L + + ++ + +E+Q++ + +L++++ N ++I Sbjct: 711 QYFELNTLKQQVLKEVVKEVIEVPSQSDQILIKELRQELQQLQSEYRILNAQKQNY-VEI 769 Query: 1084 LVREQDDQIKELKETKLT----FEMNIPKTEGMIISSTIEPMSDDANNV---DXXXXXXX 1136 ++IKEL++ +T +E K + I D + + Sbjct: 770 QSEVDKNRIKELEKQLITLRRDYEEVCNKKQSQITEFVEVSSKQDLQRIQQLEKIVQQLQ 829 Query: 1137 XXXXXLKVQEEEEFI------QERSVLQEQSAKLNTELQECYTKIIQLETLNTEL---TG 1187 L++Q E+ Q+R +QE S +L T QE QL N L Sbjct: 830 EENFKLQIQSNEQIKKSVIVNQDREQVQELSVQLATLKQENKALHQQLNQQNESLRKSQN 889 Query: 1188 HDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQRE 1247 D + +Q+ Q LEQ N E N S + ++ ++ + D+ F+I +L Q L + Sbjct: 890 SDFLKIQQLEQKIRILEQSNFEVQNQQSQIKIVKETVEVSKDEDVFKIQQLELQ-LQVKT 948 Query: 1248 ADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLR 1307 D Q E +L +Q + E+L+ + + E T + ++ S ++LQ K + Sbjct: 949 DDIQYLEKQLNLQ----KKNVEELISANEKMKYENTKMRQQLYELQSSIDELQLKIKENN 1004 Query: 1308 NLQE---KYADVINQI---EILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQ 1361 QE +Y +I+Q E L+++ ++ + Q Y+ Sbjct: 1005 QFQEETKQYKQMISQYEQREKLKNDSQELVTELKRKLNESENQIKRQWGEFELSKQDYEF 1064 Query: 1362 MQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTH 1421 + N++ QL++ ++ K Q+++++ E+ ++ + Sbjct: 1065 KLKSQETKYNQQIQQLQQ-EFQMKQQSKEDEYYISKNSFK------QMQMQNDELQREIN 1117 Query: 1422 EYTITLTQRNDEFENVRQQLVEYEKRIEDLTYE-KESELAILRLKMHENANHYETMQKES 1480 + + Q++DE + + ++ Y +++ KE+++ I + + + MQK + Sbjct: 1118 RLSDLIRQKSDEIKKLNDKISAYAVKLDQQQSNLKENQIQIQDYSLQQE-KMSQLMQKNN 1176 Query: 1481 EIER-VKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDE 1539 ++E +K EE K E++ L+KQ ++E + K + L N IVTL ++ Sbjct: 1177 KLENALKQFEE--EKKIENLELHKQFNIKVMEIQEIIQKKDNEIQQLSNY---IVTLKEQ 1231 Query: 1540 ITNLQN 1545 I N +N Sbjct: 1232 IKNQEN 1237 Score = 114 bits (275), Expect = 2e-23 Identities = 162/781 (20%), Positives = 348/781 (44%), Gaps = 81/781 (10%) Query: 445 KDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEK 504 KDT I Q L ++H + + G + ++ +QL+ +L D+ +N+K K Sbjct: 525 KDT-INQYMLIIEEHQQRNN----GVFENQIQQLQLQLDQLQIKLRDQESQLNIKS--SK 577 Query: 505 LKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSK----VSDSNKEIVR- 559 E QI + K++++Q++ +DN K + E+++ Sbjct: 578 CFDLERQIEVEKLRFSERESLFSQQLKQEKIRIQQLELQVDNLQKDMALQNQKRNEVIKE 637 Query: 560 -LTEELHHLSQKVAELEEEKGNLQL-HLVDYDSGRMIESDVYKKMIEMENLA---ETRLK 614 + E +++ LE+ NLQ +L+ + +++ ++I++E L E + K Sbjct: 638 YIYVENQQDQERIILLEQSLQNLQQEYLLMKEQYICVQNQYNAQIIQIEQLQGLQEDKSK 697 Query: 615 AISLLESQKF--DLVQELHIL-QQKYDEVEDKLADISQLQSDQVC-SEIKSV--HLEEQI 668 L E + D EL+ L QQ EV ++ ++ QSDQ+ E++ L+ + Sbjct: 698 IRQLEEQLRMLKDQYFELNTLKQQVLKEVVKEVIEVPS-QSDQILIKELRQELQQLQSEY 756 Query: 669 DALSASKKELALVIENLKLDK-EQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKM 727 L+A K+ + + ++ ++L + L D E++ NK Q+ I E ++++ K + Sbjct: 757 RILNAQKQNYVEIQSEVDKNRIKELEKQLITLRRDYEEVCNKKQSQITEFVEVSSKQDLQ 816 Query: 728 SAEKISELLAKINHEEQSKIQTQFGIDAK-----------IQERDLYIENIESE------ 770 +++ +++ ++ EE K+Q Q K +QE + + ++ E Sbjct: 817 RIQQLEKIVQQLQ-EENFKLQIQSNEQIKKSVIVNQDREQVQELSVQLATLKQENKALHQ 875 Query: 771 --------LSKYKS----RICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTI 818 L K ++ +I +LE+ I ++E + ++ + Q+ + + + E Sbjct: 876 QLNQQNESLRKSQNSDFLKIQQLEQKIRILEQSNFEVQNQQSQIKIVKETVEVSKDEDVF 935 Query: 819 QEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNA 878 + +L +L V D + +EKQL + +EL N+ + EN ++ L ++Q + Sbjct: 936 KIQQLELQLQVKTDDIQYLEKQLNLQKKNVEELISANEKMKYENTKMRQQLYELQSSIDE 995 Query: 879 LVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIES 938 L K + + E+ +Y+ + E +++ ++ Q L+ + K+++ + E QI+ Sbjct: 996 LQLKIKENNQFQEETKQYKQMISQYEQR-EKLKNDSQELVTELKRKLNESE----NQIKR 1050 Query: 939 AIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMN--VEELNKMNLELIDKHVQKQ 996 + ++ + YE +L++Q +Y I+ L +++ +K + I K+ KQ Sbjct: 1051 QWGEFELSKQDYE------FKLKSQETKYNQQIQQLQQEFQMKQQSKEDEYYISKNSFKQ 1104 Query: 997 QTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQV---SYMSMVSDYESKLAQF 1053 D ++ EIN+L+ L++QK +EI LN KI+ V S + + + ++ + Sbjct: 1105 MQMQNDELQR---EINRLSDLIRQKSDEIKKLNDKISAYAVKLDQQQSNLKENQIQIQDY 1161 Query: 1054 TTKLENMEEEMQRVSKQLLDSKQHNEELQI----LVREQDDQIKELKETKLTFEMNIPKT 1109 + + E M + MQ+ +K KQ EE +I L ++ + ++ E++E + I + Sbjct: 1162 SLQQEKMSQLMQKNNKLENALKQFEEEKKIENLELHKQFNIKVMEIQEIIQKKDNEIQQL 1221 Query: 1110 EGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEE--EEFIQERSVLQEQSAKLNTE 1167 I++ E + + NN L+ Q ++ + ++ L+E+ N E Sbjct: 1222 SNYIVTLK-EQIKNQENNKSQKQNDNQQFLIDLQNQLSIVKQDLMRQTTLKEEYQNKNNE 1280 Query: 1168 L 1168 L Sbjct: 1281 L 1281 Score = 99.5 bits (237), Expect = 7e-19 Identities = 224/1084 (20%), Positives = 467/1084 (43%), Gaps = 143/1084 (13%) Query: 504 KLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEE 563 K + ++ I+ D + NK + +KS + QK + ++S + +E+ R+ + Sbjct: 51 KREEQKQGISYYRDLCEQLNKENLLLKSFQIENNELKQKLLLINVELSAAQQELSRIRNQ 110 Query: 564 LHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQK 623 L SQ+ + +K +Q VD ++ E + YK+ +E E + +E+Q Sbjct: 111 LG--SQQPTDRYIQK--IQQDNVDLQQ-QINEQNKYKQKLEAELKFYKDNRFTQTIETQD 165 Query: 624 FDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIE 683 + Q Q+K E+ED DI L SD ++ K LE+ AL+ K++ Sbjct: 166 MNFSQN----QRKIKEMED---DIQILISDYSRNQEK---LEK---ALNEQKQQS----- 207 Query: 684 NLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEE 743 K D +Q+ I+ L + + + QN ++L +KL + E +L+ K ++ E Sbjct: 208 --KYDIDQMKSQIQSLSSQIQGWQQRYQNLEIMKIELENKLIILEKEN-QQLIGKSSYRE 264 Query: 744 QSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLG 803 +Q +D Q +D + + +++ K+ I + ++S + + +L++K +Q Sbjct: 265 -----SQANLDTVSQLKDQIYQQFK-QINDLKAEIQQKQQSEYQLIKEQQNLKQKLEQ-- 316 Query: 804 SYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQ 863 + + Y+ ++ + VN + L + +E+ L+ E+EN QK N L + Sbjct: 317 ----SQSQTYNSQQVENTQYVNEIFKLKQY---IEQ--LQYENENYRTQKSN--LYQNQT 365 Query: 864 NLQISLSDMQQHYNALVEKANRTD-LAESESTKYQTQLRDLESNLKRITHEHQTLIVQKK 922 N+ Q NA +E+ R S T+Y+ QL D E+ + V ++ Sbjct: 366 NISSKEVQQNQQINAYLEEIERLKGNIFSLQTQYEKQLNDQENRFQIELKSVSDKFVSQQ 425 Query: 923 KEI-------EDLEIEFNTQIESAIRD--KKVLNEKYEKNIEYVTQLEAQLQEYKNNI-E 972 KE+ E+ F Q + D K+ +K+ + L + QE +N + + Sbjct: 426 KELNCKTQIFEESRFTFQNQQQIQENDIQTKIWQDKFYEQQTLNEDLMYKHQELRNQLTQ 485 Query: 973 NLNMNVE-ELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQK 1031 LN + E ++ ++ ++ V++QQ ++ ++ + +N + II +Q+ Sbjct: 486 YLNYKTQNEYDQKTIQNLEALVEEQQNIMHSLYQKELHYKDTINQYML-----IIEEHQQ 540 Query: 1032 INNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQ 1091 NN + + + + +L Q KL + E ++ S + D ++ E ++ E++ Sbjct: 541 RNNGV--FENQIQQLQLQLDQLQIKLRDQESQLNIKSSKCFDLERQIEVEKLRFSERESL 598 Query: 1092 I-KELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEF 1150 ++LK+ K+ + + + + ++ + N V + V+ +++ Sbjct: 599 FSQQLKQEKIRIQQLELQVDNLQKDMALQ--NQKRNEV---------IKEYIYVENQQD- 646 Query: 1151 IQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQL---KSKLEQLN 1207 QER +L EQS + LQ+ Y + + ++ EQ+ L KSK+ QL Sbjct: 647 -QERIILLEQSLQ---NLQQEYLLMKEQYICVQNQYNAQIIQIEQLQGLQEDKSKIRQLE 702 Query: 1208 TENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESK 1267 + L EL + + + E+ E+ Q +D Q ELR +L +S+ Sbjct: 703 EQLRMLKDQYFELNTLKQQVLKEVVKEVIEVPSQ------SD-QILIKELRQELQQLQSE 755 Query: 1268 YEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEI 1327 Y L ++ N + +V +N++++ E+ L L+ Y +V N+ + +E Sbjct: 756 YRIL-------NAQKQNYVEIQSEVD--KNRIKELEKQLITLRRDYEEVCNKKQSQITEF 806 Query: 1328 EDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXX 1387 + ++ + +Q+QE++ + N Q+KKS Sbjct: 807 VE-------------VSSKQDLQRIQQLEKIVQQLQEENFKLQIQSNEQIKKSVI----- 848 Query: 1388 XXXXXXRVNDAEAKVLELTHQLELKDSE---IYQKTHEYTITLTQ-RNDEFENVRQQLVE 1443 VN +V EL+ QL E ++Q+ ++ +L + +N +F + QQL + Sbjct: 849 -------VNQDREQVQELSVQLATLKQENKALHQQLNQQNESLRKSQNSDFLKI-QQLEQ 900 Query: 1444 YEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIE-ELNVKITESVSLN 1502 + +E +E +++ + +++ + E + K+ ++ +++ +E +L VK + L Sbjct: 901 KIRILEQSNFEVQNQQSQIKI-VKETVE----VSKDEDVFKIQQLELQLQVKTDDIQYLE 955 Query: 1503 KQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFAS 1562 KQ+ K +EE ++ A E + E + ++ LQ+ + KI+++ F Sbjct: 956 KQLNLQKKNVEELIS-------ANEKMKYENTKMRQQLYELQSSIDELQLKIKENNQFQE 1008 Query: 1563 DTKQ 1566 +TKQ Sbjct: 1009 ETKQ 1012 Score = 96.3 bits (229), Expect = 6e-18 Identities = 114/636 (17%), Positives = 296/636 (46%), Gaps = 37/636 (5%) Query: 477 EIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDE---IDAANKNMIKVKSN- 532 E+ +++Q+ +E+ E+ +V + +K +++ QL E ++A +N ++++S Sbjct: 714 ELNTLKQQVLKEVVKEVIEVPSQSDQILIKELRQELQQLQSEYRILNAQKQNYVEIQSEV 773 Query: 533 HKLKLKQMQKTIDNFSKVSDS--NKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDS 590 K ++K+++K + + + NK+ ++TE + S++ + ++ + L + + Sbjct: 774 DKNRIKELEKQLITLRRDYEEVCNKKQSQITEFVEVSSKQDLQRIQQLEKIVQQLQEENF 833 Query: 591 GRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQL 650 I+S+ K + N +++ +S+ Q L QE L Q+ ++ + L Sbjct: 834 KLQIQSNEQIKKSVIVNQDREQVQELSV---QLATLKQENKALHQQLNQQNESLRKSQNS 890 Query: 651 QSDQVCSEIKSVHLEEQID-ALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNK 709 ++ + + + EQ + + + ++ +V E +++ K++ I+ LE + + Sbjct: 891 DFLKIQQLEQKIRILEQSNFEVQNQQSQIKIVKETVEVSKDEDVFKIQQLELQLQVKTDD 950 Query: 710 LQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYI-EN-- 766 +Q Y+++ ++L +K + E++ K+ +E Q + + + I E L I EN Sbjct: 951 IQ-YLEKQLNL----QKKNVEELISANEKMKYENTKMRQQLYELQSSIDELQLKIKENNQ 1005 Query: 767 IESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNR 826 + E +YK I + E+ + D + + +L + ++ + E+ + + + + Sbjct: 1006 FQEETKQYKQMISQYEQREKLKNDSQELVTELKRKLNESENQIKRQWGEFELSKQDYEFK 1065 Query: 827 LAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEEN--QNLQISLSDMQQHYNALVE--- 881 L + + Q L+ E + K+ K+++ + +N + +Q+ ++Q+ N L + Sbjct: 1066 LKS-QETKYNQQIQQLQQEFQMKQQSKEDEYYISKNSFKQMQMQNDELQREINRLSDLIR 1124 Query: 882 -KANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAI 940 K++ + + Y +L +SNLK + Q +Q++K + L ++ N ++E+A+ Sbjct: 1125 QKSDEIKKLNDKISAYAVKLDQQQSNLKENQIQIQDYSLQQEK-MSQL-MQKNNKLENAL 1182 Query: 941 RDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELID--KHVQKQQT 998 K+ EK +N+E Q ++ E + I+ + +++L+ + L + K+ + ++ Sbjct: 1183 --KQFEEEKKIENLELHKQFNIKVMEIQEIIQKKDNEIQQLSNYIVTLKEQIKNQENNKS 1240 Query: 999 QSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYES------KLAQ 1052 Q + +Q++ ++ +++KQ L ++ N + +++YE K Sbjct: 1241 QKQNDNQQFLIDLQNQLSIVKQDLMRQTTLKEEYQNKNNELLLKIAEYEKGNRISVKSDY 1300 Query: 1053 FTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQ 1088 F T++ + + +D Q++ + QI +++ Sbjct: 1301 FVTEMYQGTGSFRNLGNASVDFNQNDSQFQIASQQR 1336 Score = 69.3 bits (162), Expect = 8e-10 Identities = 114/559 (20%), Positives = 248/559 (44%), Gaps = 48/559 (8%) Query: 216 QQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLA 275 Q T QEN A+ + + + L K S ++I LE+ ++LE + FE+ + S++ Sbjct: 862 QLATLKQENK-ALHQQLNQQNESLRKSQNSDFLKIQQLEQKIRILEQSNFEVQNQQSQIK 920 Query: 276 QELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLN 335 E L Q ++ ++ +E++ +L+ N+ EL E +++ N Sbjct: 921 IVKETVEVSKDEDVFKIQQLELQ-LQVKTDDIQYLEKQLNLQKKNVEELISANEKMKYEN 979 Query: 336 CQIRQTNKELENKLATMG---TESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSE 392 ++RQ EL++ + + E+ +K+ +IS+ R K+K+ S+ Sbjct: 980 TKMRQQLYELQSSIDELQLKIKENNQFQEETKQYKQMISQYEQR---EKLKN-----DSQ 1031 Query: 393 TLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQL 452 L + +K+N++E +++ D E+ + ++T + I QL Sbjct: 1032 ELVTELKRKLNESE-NQIKRQWGEFELSKQDYEFKLKSQETKY----------NQQIQQL 1080 Query: 453 QLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQI 512 Q E Q + + ED I+K + Q NDE++ + L + ++ ++I Sbjct: 1081 QQEFQMKQQ---------SKEDEYYISKNSFKQMQMQNDELQR-EINRLSDLIRQKSDEI 1130 Query: 513 TQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVA 572 +LND+I A + + +SN LK+ Q I ++S + ++++ +L + + K Sbjct: 1131 KKLNDKISAYAVKLDQQQSN----LKENQIQIQDYSLQQEKMSQLMQKNNKLEN-ALKQF 1185 Query: 573 ELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHI 632 E E++ NL+LH I+ + KK E++ L+ + +++Q+ + Q+ + Sbjct: 1186 EEEKKIENLELHKQFNIKVMEIQEIIQKKDNEIQQLSNYIVTLKEQIKNQENNKSQKQND 1245 Query: 633 LQQKYDEVEDKLADISQ--LQSDQVCSEIKSVHLEEQIDALSASK-KELALVIENLKLDK 689 QQ +++++L+ + Q ++ + E ++ + E + K +++ + + Sbjct: 1246 NQQFLIDLQNQLSIVKQDLMRQTTLKEEYQNKNNELLLKIAEYEKGNRISVKSDYFVTEM 1305 Query: 690 EQLYGTIKDLENDKEDI-MNKLQNYIQENMDLTD--KLEKMSAEKISELLAKINHEEQSK 746 Q G+ ++L N D N Q I + D +++ A + L + +N +Q + Sbjct: 1306 YQGTGSFRNLGNASVDFNQNDSQFQIASQQRIRDSTRMQNPKANNFNPLNSFVNIFKQFR 1365 Query: 747 IQTQFGIDAKIQERDLYIE 765 Q ++ +++R YIE Sbjct: 1366 ---QLNNNSLLRKRVEYIE 1381 Score = 66.9 bits (156), Expect = 4e-09 Identities = 110/595 (18%), Positives = 242/595 (40%), Gaps = 43/595 (7%) Query: 990 DKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESK 1049 ++ +++Q Q Y ++NK N LLK E L QK+ V +S S+ Sbjct: 48 EQRKREEQKQGISYYRDLCEQLNKENLLLKSFQIENNELKQKLLLINVE-LSAAQQELSR 106 Query: 1050 LAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKT 1109 + + + +Q++ + +D +Q E ++ + ++K K+ + T + Sbjct: 107 IRNQLGSQQPTDRYIQKIQQDNVDLQQQINEQNKYKQKLEAELKFYKDNRFTQTIETQDM 166 Query: 1110 EGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQ 1169 I+ M DD + +++++ + ++ Q L++++Q Sbjct: 167 NFSQNQRKIKEMEDDIQILISDYSRNQEKLEKALNEQKQQSKYDIDQMKSQIQSLSSQIQ 226 Query: 1170 ECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVD 1229 + LE + EL ++ +++ QL K E+ L TV++L+ I Sbjct: 227 GWQQRYQNLEIMKIELENKLIILEKENQQLIGKSSY--RESQANLDTVSQLKDQIYQQFK 284 Query: 1230 QRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTM 1289 Q AE+ Q Q E K + L+ +L E Q +S Q + N+I + Sbjct: 285 QINDLKAEI--QQKQQSEYQLIKEQQNLKQKL---EQSQSQTYNSQQVENTQYVNEIFKL 339 Query: 1290 EQ-VTSLQNKLQDKEEHLRNLQEKYADV----INQIEILRSEIED-EKVAFXXXXXXXXX 1343 +Q + LQ + ++ NL + ++ + Q + + + +E+ E++ Sbjct: 340 KQYIEQLQYENENYRTQKSNLYQNQTNISSKEVQQNQQINAYLEEIERLKGNIFSLQTQY 399 Query: 1344 XXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVL 1403 + R + + K + ++ + E N + + + ND + K+ Sbjct: 400 EKQLNDQENRFQIE-LKSVSDKFVSQQKELNCKTQIFEESRFTFQNQQQIQENDIQTKIW 458 Query: 1404 E--------LTHQLELKDSEIYQKTHEYTITLTQRNDEFENVR--QQLVEYEKRIEDLTY 1453 + L L K E+ + +Y TQ + + ++ + LVE ++ I Y Sbjct: 459 QDKFYEQQTLNEDLMYKHQELRNQLTQYLNYKTQNEYDQKTIQNLEALVEEQQNIMHSLY 518 Query: 1454 EKESELA------ILRLKMHENANHYETMQKESEIERVKL-IEELNVKITESVS-LN--- 1502 +KE +L ++ H+ N+ E++I++++L +++L +K+ + S LN Sbjct: 519 QKELHYKDTINQYMLIIEEHQQRNNGVF---ENQIQQLQLQLDQLQIKLRDQESQLNIKS 575 Query: 1503 KQVAELNKALEEEVAKTNEMQT----ALENQEIEIVTLNDEITNLQNMVRASSSK 1553 + +L + +E E + +E ++ L+ ++I I L ++ NLQ + + K Sbjct: 576 SKCFDLERQIEVEKLRFSERESLFSQQLKQEKIRIQQLELQVDNLQKDMALQNQK 630 >UniRef50_A7DN60 Cluster: Chromosome segregation ATPase-like protein; n=1; Candidatus Nitrosopumilus maritimus SCM1|Rep: Chromosome segregation ATPase-like protein - Candidatus Nitrosopumilus maritimus SCM1 Length = 1206 Score = 126 bits (305), Expect = 4e-27 Identities = 222/1107 (20%), Positives = 479/1107 (43%), Gaps = 107/1107 (9%) Query: 474 DVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMI----KV 529 +++ + K E + EL + + K L EK+ S + ++ +L E D A K KV Sbjct: 142 ELDALKKTYESSQTELQE-----SKKQLEEKIYSQQSELERLRGERDLAKKEAEFESKKV 196 Query: 530 KSNHKL--KLKQMQKTIDNFSK-----VSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQ 582 +L K+KQ Q+ + S+ ++ E +L E++H ++ L +++ + Sbjct: 197 VEQAELEEKIKQQQEELSQLSRDYSVATRKASLEKAKLEEQIHVQQAELERLAQDREETE 256 Query: 583 LHLVDYDSGRM----IESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQ-KY 637 H + + ++ +E + + ++E LA+ R E + DL +++ + +Q + Sbjct: 257 -HKMSLEKAKLEKMKLEEKIATQQTQLEKLAKDRELLAKKSEQETNDL-EKISLTEQIRA 314 Query: 638 DEVE-DKLA-DISQLQ----SDQVCSEIKSVHLEEQIDALSASKK--ELALVIENLKLDK 689 E E +K+A D ++ +D+ E K L+ ++ A+S + E L E L+ Sbjct: 315 QEAELEKMAHDYESVKRKATADKAMLEEKIQTLQVELKAISEERSTFEKKLASEKAALE- 373 Query: 690 EQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQT 749 EQLY LEN + N + N Q+ DL + L++ AE + IN + QSKI+ Sbjct: 374 EQLYIQQVQLENLSKS--NSINNE-QQITDLENNLQEKQAE-----IDTINKQHQSKIE- 424 Query: 750 QFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEK 809 Q + + + + E + +K KS ++E + D ++K QL ++E Sbjct: 425 QIQSEKIALQNKIQSQQAELDATKSKSSSAKMESQLQSQVD---DYKKKHAQLDDIMKEY 481 Query: 810 QKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISL 869 Q S+ ++ L ++ L + + + E E+K +K Q L+E Q SL Sbjct: 482 QAVMSKSQSEKTALHEKIQTLQAELDATKSKSISPELESKLTLQKEQ--LQEKQAEIYSL 539 Query: 870 SDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLE 929 + +QH + L + + + + Q +L +++S I+ E ++ + +K+++E + Sbjct: 540 T--RQHQSKLEQVQSEKTALQKQLDSKQAELEEIKSK-PTISPELESQLALQKEQLESKQ 596 Query: 930 IEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELN-KMNLEL 988 E +T + K+ + EK T L+ L+ K +E L + L L Sbjct: 597 AEIDTITKQ--HQSKLEQVQSEK-----TTLQKLLEVQKAELEELKSKSPSPELESQLAL 649 Query: 989 IDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYES 1048 + ++ +Q + T+Q+ ++ L+Q E IAL KI Q + + +S Sbjct: 650 QKEQLESKQAEIDTITKQHQSK-------LEQVQSEKIALQNKIEFQQTK----LEEIKS 698 Query: 1049 KLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPK 1108 K T +E ++ + K+ L+SKQ E+ L ++ ++++++ K + + Sbjct: 699 K----PTSYPKLESQLA-LQKEQLESKQ--AEIDALTKQHQSKLEQVQSEKTALQKQLES 751 Query: 1109 TEGMI--ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNT 1166 + + I S P + ++ ++ + +++ +Q + L Sbjct: 752 KQAELDTIQSKSSPKLESQLTLERQELQKKQAEIDALTKQHQSKLEQ---VQSEKTALQN 808 Query: 1167 ELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISS 1226 +++ +K+ +L++ + + E+ QL+SK +++T S + +++S ++ Sbjct: 809 KVKFQQSKLEELKSKSPSSKIESQLTLER-EQLESKQAEIDTITKQYQSKLEQVQSEKTA 867 Query: 1227 AVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKI 1286 ++ F+ ++L + + + + + E +L +Q ESK ++ D++ Q + +I Sbjct: 868 LQNKVKFQQSQL--EEIKSKPTSYPELESKLTLQKEQLESKQAEI-DTITKQHQSKLEQI 924 Query: 1287 VTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXX 1346 + T+LQ ++ + L+ L + + L ++ ++ + Sbjct: 925 --QSEKTALQKQVNSQHADLKKLTAERKE-------LEKKLSSKQTSLVQSGQEESVDKK 975 Query: 1347 XXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELT 1406 +S + + LN AQ+K++ ++ E +++ Sbjct: 976 PSWLSKILGKKSKARPVDPVSLNEKLLQAQIKEAEAGATVTNDLRTQQIKLVE--LMKKR 1033 Query: 1407 HQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKM 1466 + E K S++ E I Q DE E Q V E+R E++++ LR K Sbjct: 1034 DEAE-KKSQVISPALEKQIQKLQ--DELEKFEQISVLAEQRALKKKESLEAQISSLREKE 1090 Query: 1467 HENANHYETMQKES-EIERV-KLIEELNVKITESV-----SLNKQVAELNKALEEEV-AK 1518 EN E++++E ++E+ + E+ +K+ E + ++ A++ + L+ +V K Sbjct: 1091 FENKMRMESLEQEKIDLEKSHQDHEDQMIKLAEDEMQIIDQIKREKAQIRRLLQTQVKLK 1150 Query: 1519 TNEMQTALENQEIEIVTLNDEITNLQN 1545 + +T+ E QE E+ + D+I L N Sbjct: 1151 EHMSKTSAEVQE-ELKEIEDQILFLIN 1176 Score = 120 bits (290), Expect = 3e-25 Identities = 207/1088 (19%), Positives = 457/1088 (42%), Gaps = 66/1088 (6%) Query: 498 VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEI 557 ++DLI + K ++ + + I NK + K + + + + T D S I Sbjct: 13 LEDLIAQNKGDVGRLRHILNSIKN-NKVLAKSDKQYLEEKVEQEYTADETQPPEQSIDFI 71 Query: 558 VRLTEELHHLSQKVAE-LEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAI 616 +L E S ++ L K +H D + + Y ++ + ++ T + Sbjct: 72 SKLVSEGFGDSNRLRYILHSLKQGKTIHASDKNYLDSVTQSYYAEVAQKKSSESTTVS-- 129 Query: 617 SLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKK 676 S ++ + EL L++ Y+ + +L + + +++ S+ LE +KK Sbjct: 130 STIDEEHKQKQSELDALKKTYESSQTELQESKKQLEEKIYSQ--QSELERLRGERDLAKK 187 Query: 677 ELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELL 736 E E+ K+ ++ +LE E I + + Q + D + K S EK ++L Sbjct: 188 EAEF--ESKKVVEQA------ELE---EKIKQQQEELSQLSRDYSVATRKASLEK-AKLE 235 Query: 737 AKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLE 796 +I H +Q++++ + D + E + +E + E K + +I + + + R L Sbjct: 236 EQI-HVQQAELE-RLAQDREETEHKMSLEKAKLEKMKLEEKIATQQTQLEKLAKDRELLA 293 Query: 797 RKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLE---IEHENKELQK 853 +K++Q + L EK + QE EL ++A D++ V K + +E + + LQ Sbjct: 294 KKSEQETNDL-EKISLTEQIRAQEAEL-EKMA--HDYESVKRKATADKAMLEEKIQTLQV 349 Query: 854 KNQILLEENQNLQISLSDMQQ--HYNALVEKANRTDLAESESTKYQTQLRDLESNLKRIT 911 + + + EE + L+ + +++ +L++S S + Q+ DLE+NL+ Sbjct: 350 ELKAISEERSTFEKKLASEKAALEEQLYIQQVQLENLSKSNSINNEQQITDLENNLQEKQ 409 Query: 912 HEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNI 971 E T+ Q + +IE ++ E +++ I+ ++ + K+ ++E+QLQ ++ Sbjct: 410 AEIDTINKQHQSKIEQIQSE-KIALQNKIQSQQAELDA-TKSKSSSAKMESQLQSQVDDY 467 Query: 972 ENLNMNVEELNKMNLELIDK-HVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQ 1030 + + ++++ K ++ K +K T Q + K ++ + + ++ + Sbjct: 468 KKKHAQLDDIMKEYQAVMSKSQSEKTALHEKIQTLQAELDATKSKSISPELESKLTLQKE 527 Query: 1031 KINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQH---NEELQILVRE 1087 ++ Q S+ ++SKL Q ++ +++++ +L + K + EL+ + Sbjct: 528 QLQEKQAEIYSLTRQHQSKLEQVQSEKTALQKQLDSKQAELEEIKSKPTISPELESQLAL 587 Query: 1088 QDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEE 1147 Q +Q+ E K+ ++ I K S +E + + + LK + Sbjct: 588 QKEQL-ESKQAEID---TITKQH----QSKLEQVQSEKTTLQKLLEVQKAELEELKSKSP 639 Query: 1148 EEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLN 1207 ++ + LQ++ +L ++ E T Q ++ ++ + Q +I ++KLE++ Sbjct: 640 SPELESQLALQKE--QLESKQAEIDTITKQHQSKLEQVQSEKIALQNKIEFQQTKLEEIK 697 Query: 1208 TENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQRE------ADFQKTEHELRVQL 1261 ++ + ++L ++ + EI L KQH ++ E QK + +L Sbjct: 698 SKPTSYPKLESQLALQ-KEQLESKQAEIDALTKQHQSKLEQVQSEKTALQKQLESKQAEL 756 Query: 1262 SAFESKYEQLLDS-VQSSTQEETNKIVTMEQVTSL-QNKLQDKEEHLRNLQEKYADVINQ 1319 +SK L+S + QE K ++ +T Q+KL+ + LQ K ++ Sbjct: 757 DTIQSKSSPKLESQLTLERQELQKKQAEIDALTKQHQSKLEQVQSEKTALQNKVKFQQSK 816 Query: 1320 IEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKK 1379 +E L+S+ K+ D T+ K Q QS + + ++ Sbjct: 817 LEELKSKSPSSKIESQLTLEREQLESKQAEIDTITKQYQSKLEQVQSEKTALQNKVKFQQ 876 Query: 1380 SSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQ 1439 S + E+K+ QLE K +EI T ++ L Q E +++ Sbjct: 877 SQLEEIKSKPTSYPEL---ESKLTLQKEQLESKQAEIDTITKQHQSKLEQIQSEKTALQK 933 Query: 1440 QLVEYEKRIEDLTYEK---ESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKIT 1496 Q+ ++ LT E+ E +L+ + + ++ +K S + ++ L ++ + Sbjct: 934 QVNSQHADLKKLTAERKELEKKLSSKQTSLVQSGQEESVDKKPSWLSKI-LGKKSKARPV 992 Query: 1497 ESVSLNKQVAELN-KALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQ 1555 + VSLN+++ + K E TN+++T Q+I++V L + + + S ++ Sbjct: 993 DPVSLNEKLLQAQIKEAEAGATVTNDLRT----QQIKLVELMKKRDEAEKKSQVISPALE 1048 Query: 1556 KHVSFASD 1563 K + D Sbjct: 1049 KQIQKLQD 1056 Score = 100 bits (239), Expect = 4e-19 Identities = 165/853 (19%), Positives = 371/853 (43%), Gaps = 80/853 (9%) Query: 763 YIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDE 822 Y E + + S+ + ++E + +L++ + + LQE +K E + Sbjct: 114 YAEVAQKKSSESTTVSSTIDEEHKQKQSELDALKKTYESSQTELQESKKQLEEKIYSQQS 173 Query: 823 LVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEK 882 + RL +R + K+ E E E+K++ ++ + L E+ + Q LS + + Y+ K Sbjct: 174 ELERLR----GERDLAKK--EAEFESKKVVEQAE-LEEKIKQQQEELSQLSRDYSVATRK 226 Query: 883 ANRTDLAESESTKYQTQLRDLESNLKRITH-----EHQTLIVQKKKEIEDLEIEF---NT 934 A+ E K + Q+ ++ L+R+ EH+ + + K E LE + T Sbjct: 227 ASL------EKAKLEEQIHVQQAELERLAQDREETEHKMSLEKAKLEKMKLEEKIATQQT 280 Query: 935 QIESAIRDKKVLNEKYEKNIEYVTQ--LEAQLQEYKNNIENLNMNVEELNKMNLELIDKH 992 Q+E +D+++L +K E+ + + L Q++ + +E + + E + + DK Sbjct: 281 QLEKLAKDRELLAKKSEQETNDLEKISLTEQIRAQEAELEKMAHDYESVKRK--ATADKA 338 Query: 993 VQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQ 1052 + +++ Q+ + I+E + + K+ E AL +++ QV ++ Q Sbjct: 339 MLEEKIQTLQVELKAISE--ERSTFEKKLASEKAALEEQLYIQQVQLENLSKSNSINNEQ 396 Query: 1053 FTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGM 1112 T LEN +E Q + +KQH +++ + E+ +++ + + K+ Sbjct: 397 QITDLENNLQEKQAEIDTI--NKQHQSKIEQIQSEKIALQNKIQSQQAELDATKSKSSSA 454 Query: 1113 IISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECY 1172 + S ++ DD + + + E ++ L E+ L EL Sbjct: 455 KMESQLQSQVDDYKKKHAQLDDIMKEYQAVMSKSQSE----KTALHEKIQTLQAELDATK 510 Query: 1173 TKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRG 1232 +K I E L ++LT + +EQ+ + ++++ L ++ + L V ++++ +D + Sbjct: 511 SKSISPE-LESKLT----LQKEQLQEKQAEIYSLTRQHQSKLEQVQSEKTALQKQLDSKQ 565 Query: 1233 FEIAELWKQHLAQREAD----FQKTEHELR-VQLSAFESKYEQLLDSVQS--STQEETNK 1285 E+ E+ + E + QK + E + ++ +++ L+ VQS +T ++ + Sbjct: 566 AELEEIKSKPTISPELESQLALQKEQLESKQAEIDTITKQHQSKLEQVQSEKTTLQKLLE 625 Query: 1286 I--VTMEQVTS------LQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXX 1337 + +E++ S L+++L ++E L + Q + + Q + +++ EK+A Sbjct: 626 VQKAELEELKSKSPSPELESQLALQKEQLESKQAEIDTITKQHQSKLEQVQSEKIALQNK 685 Query: 1338 XXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVND 1397 +++++ SY +++ Q L + QL+ ++ Sbjct: 686 IEFQQTKLE----EIKSKPTSYPKLESQLAL----QKEQLESKQAEIDALTKQHQSKLEQ 737 Query: 1398 AEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKES 1457 +++ L QLE K +E+ + + L + RQ+L + + I+ LT + +S Sbjct: 738 VQSEKTALQKQLESKQAELDTIQSKSSPKL---ESQLTLERQELQKKQAEIDALTKQHQS 794 Query: 1458 ELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVA 1517 K+ + + +Q + + ++ KL EEL K S K ++L E+ + Sbjct: 795 -------KLEQVQSEKTALQNKVKFQQSKL-EELKSKSPSS----KIESQLTLEREQLES 842 Query: 1518 KTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMN 1577 K E+ T + + ++ + E T LQN V+ S++++ S + + + +L T+ Sbjct: 843 KQAEIDTITKQYQSKLEQVQSEKTALQNKVKFQQSQLEEIKSKPTSYPE-LESKL--TLQ 899 Query: 1578 KELLDAVPRAELD 1590 KE L++ +AE+D Sbjct: 900 KEQLES-KQAEID 911 Score = 98.7 bits (235), Expect = 1e-18 Identities = 187/1035 (18%), Positives = 428/1035 (41%), Gaps = 78/1035 (7%) Query: 215 KQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKL 274 +++++++ ++ + EK +L + I V+ + LE + E ++SLE +KL Sbjct: 210 QEELSQLSRDYSVATRKASLEKAKLEEQIH---VQQAELERLAQDREETEHKMSLEKAKL 266 Query: 275 AQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSL--EI-ANMTELTKKIELL 331 + + ++ + E++T EK SL +I A EL K Sbjct: 267 EKMKLEEKIATQQTQLEKLAKDRELLAKKSEQETNDLEKISLTEQIRAQEAELEKMAHDY 326 Query: 332 EHLNCQIRQTNKELENKLATMGTESKAVSSP-SKKGSPLISRKSGRNTASKMKSPWSQLS 390 E + + LE K+ T+ E KA+S S L S K+ ++ + Sbjct: 327 ESVKRKATADKAMLEEKIQTLQVELKAISEERSTFEKKLASEKAALEEQLYIQQVQLENL 386 Query: 391 SETLNQDTDKKIN--KNEIAKLEMVIQSLNKDLVDK-EYVISEKDTXXXXXXXXXXGKDT 447 S++ + + +++I +N + + + I ++NK K E + SEK D Sbjct: 387 SKSNSINNEQQITDLENNLQEKQAEIDTINKQHQSKIEQIQSEKIALQNKIQSQQAELDA 446 Query: 448 L-----IAQLQLEHQQHMEGPSLIHVGTNT--EDVNEIAKVQEQLKQELNDEIKDVNVKD 500 A+++ + Q ++ H + ++ + + K L+++I+ + + Sbjct: 447 TKSKSSSAKMESQLQSQVDDYKKKHAQLDDIMKEYQAVMSKSQSEKTALHEKIQTLQAEL 506 Query: 501 LIEKLKSA----EEQITQLNDEIDAANKNMIKVKSNHKLKLKQ-------MQKTIDNFSK 549 K KS E ++T +++ + + H+ KL+Q +QK +D+ Sbjct: 507 DATKSKSISPELESKLTLQKEQLQEKQAEIYSLTRQHQSKLEQVQSEKTALQKQLDSKQA 566 Query: 550 VSDSNKEIVRLTEELH-HLSQKVAELEEEKGNLQLHLVDYDSG-RMIESD--VYKKMIEM 605 + K ++ EL L+ + +LE ++ + + S ++S+ +K++E+ Sbjct: 567 ELEEIKSKPTISPELESQLALQKEQLESKQAEIDTITKQHQSKLEQVQSEKTTLQKLLEV 626 Query: 606 ENLAETRLKAISL---LESQKFDLVQELHILQQKYDEV-EDKLADISQLQSDQVCSEIKS 661 + LK+ S LESQ ++L Q + D + + + + Q+QS+++ + K Sbjct: 627 QKAELEELKSKSPSPELESQLALQKEQLESKQAEIDTITKQHQSKLEQVQSEKIALQNKI 686 Query: 662 VHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLT 721 + +++ + + + L L KEQL +++ + +KL+ E L Sbjct: 687 EFQQTKLEEIKSKPTSYPKLESQLALQKEQLESKQAEIDALTKQHQSKLEQVQSEKTALQ 746 Query: 722 DKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRL 781 +LE AE L I + K+++Q ++ QE I++ +++S++ ++ Sbjct: 747 KQLESKQAE-----LDTIQSKSSPKLESQLTLER--QELQKKQAEIDALTKQHQSKLEQV 799 Query: 782 EESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQL 841 + ++++ + K ++L S K S+ T++ ++L ++ A Sbjct: 800 QSEKTALQNKVKFQQSKLEELKSK-SPSSKIESQLTLEREQLESKQA------------- 845 Query: 842 LEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLR 901 EI+ K+ Q K + + E LQ + Q + K ES+ T + QL Sbjct: 846 -EIDTITKQYQSKLEQVQSEKTALQNKVKFQQSQLEEIKSKPTSYPELESKLTLQKEQLE 904 Query: 902 DLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQ---IESAIRDKKVLNEKYEKNIEYVT 958 ++ + IT +HQ+ + Q + E L+ + N+Q ++ ++K L +K + Sbjct: 905 SKQAEIDTITKQHQSKLEQIQSEKTALQKQVNSQHADLKKLTAERKELEKKLSSKQTSLV 964 Query: 959 Q--LEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNA 1016 Q E + + + + + + ++ +++ + + Q + + N+ Sbjct: 965 QSGQEESVDKKPSWLSKILGKKSKARPVDPVSLNEKLLQAQIKEAEAGATVTND------ 1018 Query: 1017 LLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQ 1076 L+ + +++ L +K + A+ + E ++ + +LE E+ ++ L K+ Sbjct: 1019 -LRTQQIKLVELMKKRDEAEKKSQVISPALEKQIQKLQDELEKFEQISVLAEQRALKKKE 1077 Query: 1077 HNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXX 1136 E +RE++ + K E+ ++++ K+ I+ D+ +D Sbjct: 1078 SLEAQISSLREKEFENKMRMESLEQEKIDLEKSHQDHEDQMIKLAEDEMQIIDQIKREKA 1137 Query: 1137 XXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTEL-TGHDVVNQEQ 1195 L+ Q ++ + + + SA++ EL+E +I+ L E DV+ + Sbjct: 1138 QIRRLLQTQ-----VKLKEHMSKTSAEVQEELKEIEDQILFLINRQAEKPLSTDVI--KS 1190 Query: 1196 INQLKSKLEQLNTEN 1210 + L KL ++ ++N Sbjct: 1191 LESLNDKLNEVLSKN 1205 Score = 85.8 bits (203), Expect = 9e-15 Identities = 123/675 (18%), Positives = 293/675 (43%), Gaps = 59/675 (8%) Query: 951 EKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQS--PDYTEQYI 1008 E++I+++++L ++ N + + ++++ ++ DK+ TQS + ++ Sbjct: 65 EQSIDFISKLVSEGFGDSNRLRYILHSLKQGKTIHAS--DKNYLDSVTQSYYAEVAQKKS 122 Query: 1009 NEINKLNALL----KQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEM 1064 +E +++ + KQK E+ AL + ++Q E K+ ++LE + E Sbjct: 123 SESTTVSSTIDEEHKQKQSELDALKKTYESSQTELQESKKQLEEKIYSQQSELERLRGER 182 Query: 1065 QRVSKQL-LDSKQHNE--ELQILVREQDDQIKELKE--TKLTFEMNIPKTEGMIISSTIE 1119 K+ +SK+ E EL+ +++Q +++ +L + T + ++ K + + I Sbjct: 183 DLAKKEAEFESKKVVEQAELEEKIKQQQEELSQLSRDYSVATRKASLEKAK---LEEQIH 239 Query: 1120 PMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLE 1179 + + K + E+ ++E+ Q+ + + +E K + E Sbjct: 240 VQQAELERLAQDREETEHKMSLEKAKLEKMKLEEKIATQQTQLEKLAKDRELLAKKSEQE 299 Query: 1180 TLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELW 1239 T + E + EQI +++LE++ + +++ + +++ A+ + + ++ Sbjct: 300 TNDLE----KISLTEQIRAQEAELEKMAHDYESV-----KRKATADKAMLEEKIQTLQVE 350 Query: 1240 KQHLAQREADFQKTEHELRVQLSAFESKYEQL-LDSVQSSTQEETNKIVTMEQVTSLQNK 1298 + +++ + F+K +L + +A E EQL + VQ ++N I +Q+T L+N Sbjct: 351 LKAISEERSTFEK---KLASEKAALE---EQLYIQQVQLENLSKSNSINNEQQITDLENN 404 Query: 1299 LQDKEEHLRNLQEKYADVINQIE----ILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRT 1354 LQ+K+ + + +++ I QI+ L+++I+ ++ + Sbjct: 405 LQEKQAEIDTINKQHQSKIEQIQSEKIALQNKIQSQQAELDATKSKSSSAKMESQLQSQV 464 Query: 1355 ENQSYKQMQEQSIL---------NINEENAQLKKSSXXXXXXXXXXXXRVN-DAEAKVLE 1404 ++ K Q I+ + +E+ A +K ++ + E+K+ Sbjct: 465 DDYKKKHAQLDDIMKEYQAVMSKSQSEKTALHEKIQTLQAELDATKSKSISPELESKLTL 524 Query: 1405 LTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIED------LTYEKESE 1458 QL+ K +EIY T ++ L Q E +++QL + +E+ ++ E ES+ Sbjct: 525 QKEQLQEKQAEIYSLTRQHQSKLEQVQSEKTALQKQLDSKQAELEEIKSKPTISPELESQ 584 Query: 1459 LAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAK 1518 LA+ + ++ +T+ K+ + KL + + K T L Q AEL + + + Sbjct: 585 LALQKEQLESKQAEIDTITKQ---HQSKLEQVQSEKTTLQKLLEVQKAELEELKSKSPSP 641 Query: 1519 TNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNK 1578 E Q AL+ +++E + EI + ++ ++Q + + + +L+ +K Sbjct: 642 ELESQLALQKEQLE--SKQAEIDTITKQHQSKLEQVQSEKIALQNKIEFQQTKLEEIKSK 699 Query: 1579 ELLDAVPRAELDLAM 1593 + P+ E LA+ Sbjct: 700 P--TSYPKLESQLAL 712 >UniRef50_A0DA04 Cluster: Chromosome undetermined scaffold_42, whole genome shotgun sequence; n=2; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_42, whole genome shotgun sequence - Paramecium tetraurelia Length = 1357 Score = 126 bits (304), Expect = 5e-27 Identities = 238/1186 (20%), Positives = 500/1186 (42%), Gaps = 120/1186 (10%) Query: 474 DVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAA---NKNMIKVK 530 + ++ + +Q+K+ L D++ +K+ E+++ ++ I +LN ++D + N+ +++ Sbjct: 97 EFQQLLRDNQQMKKTL-DQMNQ-QIKEYEEEIQRQKQVIDRLNFDLDKSKRDNEQLLQAL 154 Query: 531 SNHKLK-LKQMQKTI-DNF---SKVSDSNKEIVRLTEELHHL---SQKVAELEEEKGNLQ 582 ++ K + L Q Q + DN S + N ++ L +E++ L + K +++E Q Sbjct: 155 NDIKQRGLSQEQSLLQDNQRMKSTIDSLNNDLRSLQQEIYRLKSINDKSRYVQDESNRYQ 214 Query: 583 L-HLVDYDSGRMIESDVYKKMIEMENLAETRLKAIS-------LLESQKFDLVQELHILQ 634 + + R +E + M + E+ +A LL+ Q L Q+LH++Q Sbjct: 215 QENQANLARIRQLEMQIRDLMSKEESYQLQITRAAQGTNTENQLLKDQIAQLNQQLHMMQ 274 Query: 635 QKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKK---ELALVIENLKLDKEQ 691 ++Y + +L D+ Q Q + + +++++ + +K E ++ ++L K+Q Sbjct: 275 KQYQK---QLDDVRQDQDRMISEQRNTINIQIKDQLQRDQQKWMDEREALLHEIQLLKQQ 331 Query: 692 LYGTIKDLENDK---EDIMNKLQNYI----QENMDLTDKLEKMSAEKISELLAKINHEEQ 744 L + + ED NK Q +I Q N L +KL + + K+ +++ Sbjct: 332 LAQNELQVTRKRQLLEDEANKNQQFIVEMEQANGQLQNKLRDLQMQLQQSEKDKMRNDQY 391 Query: 745 SKIQTQFGIDAKIQERDLY-----IENIESELSKYKSRICRLEESIAVMEDRR----YSL 795 + + + + +R LY N+ S+ + K +I +L + V +D +L Sbjct: 392 VRKIDELQLQVEQLQRQLYDLTSKYNNLLSQYEQKKYQIDQLNGQLNVSQDNEKQKIMNL 451 Query: 796 ERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKN 855 ER+ +L L + Q+ + Q +E + L + + +KQL E + +EL Sbjct: 452 ERQIRELQDQLADTQRLRQQLH-QMNENYSALQITFKNS---QKQLSEADELRQELDALF 507 Query: 856 QILLEENQNLQISLSDMQQHYNALV---EKANRTDLAESESTKYQTQ-----LRDLESNL 907 Q L Q S D+ ++ L+ K ++ E E + Q Q L + ++ Sbjct: 508 QELEYYKQQDMKSKQDLDRYKQQLIIIENKHSQQSNYEIEKLRQQNQQLIDELNEWKNRN 567 Query: 908 KRITHEHQTLIVQKKKEIEDLEIE--FNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQ 965 K++ + Q IV + DL+ N + + A+ + L K ++ ++ + LE +L Sbjct: 568 KQLEGKLQQQIVMLNQAQNDLQAHQALNEKQQYALNESNQLRVKIKELLDQIQYLEMELN 627 Query: 966 EYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEI 1025 + N I++L +++++ +K LI +K+ D+ E I ++ K A L + Sbjct: 628 KKDNLIQDLQISLDQFSKQRDSLIIIEKEKK-----DF-EYRIIQLEKQLAELTMYKTQF 681 Query: 1026 IALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILV 1085 L K NN Y S+ DYE L ++ K + + + + KQ+ + Q N E++ L Sbjct: 682 QDLQFKYNNLGQEYESLRKDYE--LLRY--KYDEINNQYIQSKKQI--NIQINSEVEALK 735 Query: 1086 REQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQ 1145 E I + K T+E I + STI + + Sbjct: 736 SEIQTWIIKCK----TYESEIS-----FLRSTINDYQEIEQESEMLKQELETWQIKF-AD 785 Query: 1146 EEEEFIQERSVLQEQSAKLNTELQECYTKIIQLE-TLNTELTGHDVVNQEQ--INQLKSK 1202 + E IQ R +QE K + E +I + L + D Q+ + Q + + Sbjct: 786 ADRERIQLRQSIQEYE-KFKFRISELEREISNYKYKLESTEKERDGARQQLTILQQQRVQ 844 Query: 1203 LEQLNTENDNLLSTVAEL-RSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQL 1261 EQ+ E D+L+ E R ++S + + Q L Q+ ++ + +L ++ Sbjct: 845 FEQIKKEYDSLVYKFQEQERDNLSLRNEIENLRQQLISLQQLKQQLILIEQEKSQLLYKI 904 Query: 1262 SAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQ-I 1320 F+ + + L + S+ + + L+ KL+ + + ++++ NQ I Sbjct: 905 EEFDRERQLLKQQISSANNIKMESESLKREYEMLRMKLESSDREISTMRQQLTLASNQKI 964 Query: 1321 EI--LRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLK 1378 E LRSE + +++F + +N+ + +E ++ + E ++ + Sbjct: 965 EFDRLRSEYQQLRMSFEDSEREKQGLKQQLQIGINVKNELEQFRKEYDLIRLKFEESEKE 1024 Query: 1379 KSSXXXXXXXXXXXXRVNDAEAKVLELTHQL-ELKDSEIYQKTHEYTITLTQRNDEFENV 1437 K+ VN + ++ +L+ Q+ + + E+ K E E + Sbjct: 1025 KNQLRIQYQSSQS--NVNGYKIQIEQLSSQINQFQSQELVMKR------------EIEML 1070 Query: 1438 RQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQ-KESEIERVKLIEELNVKIT 1496 QQ+ Y+K K+ ++ + K E YE +Q K+ I+ ++ L +I Sbjct: 1071 IQQIDVYKKD----QINKQQQIQEYQFKYQEIMKEYENLQGKQKNID----VDALMYEIY 1122 Query: 1497 ESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQK 1556 E L KQ+A+ +K E E + NE + +E + ++I L EI L + +++++ Sbjct: 1123 E---LKKQLAQKDKQYEYERQEINEQKFQME-KSVKI-RLEQEIRILNEKFNSELNELRR 1177 Query: 1557 HVSFASDTKQGRDEQLDNTMNKELL----DAVPRAELDLAMYMLHQ 1598 + K + +L ++++ P ++D MY + + Sbjct: 1178 QIQIEKQEKLKLESELRIKYEQQIMQLQQQIKPSVDVDALMYEIFE 1223 Score = 111 bits (267), Expect = 2e-22 Identities = 195/975 (20%), Positives = 421/975 (43%), Gaps = 102/975 (10%) Query: 685 LKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQ 744 ++ + E L G I L+ + + Q +++N + L++M+ ++I E +I ++Q Sbjct: 73 IERENEILKGEIAKLQQFANSKVPEFQQLLRDNQQMKKTLDQMN-QQIKEYEEEIQRQKQ 131 Query: 745 SKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGS 804 + F +D ++ E + L+ K R E+S+ ++D + ++ D L + Sbjct: 132 VIDRLNFDLDKSKRDN----EQLLQALNDIKQRGLSQEQSL--LQDNQ-RMKSTIDSLNN 184 Query: 805 YLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENK---------ELQKKN 855 L+ Q QE + RL + D R V+ + + EN+ E+Q ++ Sbjct: 185 DLRSLQ--------QE---IYRLKSINDKSRYVQDESNRYQQENQANLARIRQLEMQIRD 233 Query: 856 QILLEENQNLQISLSDMQQHY-NALVEK--ANRTDLAESESTKYQTQLRDLESNLKR-IT 911 + EE+ LQI+ + + N L++ A +YQ QL D+ + R I+ Sbjct: 234 LMSKEESYQLQITRAAQGTNTENQLLKDQIAQLNQQLHMMQKQYQKQLDDVRQDQDRMIS 293 Query: 912 HEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNI 971 + T+ +Q K +++ + ++ + E+ + + ++L ++ +N VT+ L++ N Sbjct: 294 EQRNTINIQIKDQLQRDQQKWMDEREALLHEIQLLKQQLAQNELQVTRKRQLLEDEANKN 353 Query: 972 ENLNMNVEELN-KMNLELIDKHVQKQQTQSPDY-TEQYINEINKLNALLKQKDEEIIALN 1029 + + +E+ N ++ +L D +Q QQ++ +QY+ +I++L ++Q ++ L Sbjct: 354 QQFIVEMEQANGQLQNKLRDLQMQLQQSEKDKMRNDQYVRKIDELQLQVEQLQRQLYDLT 413 Query: 1030 QKINNAQVSYMSMVSDYESKLAQFTT-------KLENMEEEMQRVSKQLLDSK------- 1075 K NN Y + Q K+ N+E +++ + QL D++ Sbjct: 414 SKYNNLLSQYEQKKYQIDQLNGQLNVSQDNEKQKIMNLERQIRELQDQLADTQRLRQQLH 473 Query: 1076 QHNEE---LQILVREQDDQIKELKETK-----LTFEMNIPKTEGMIISSTIEPMSDDANN 1127 Q NE LQI + Q+ E E + L E+ K + M ++ Sbjct: 474 QMNENYSALQITFKNSQKQLSEADELRQELDALFQELEYYKQQDMKSKQDLDRYKQQLII 533 Query: 1128 VDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTG 1187 ++ Q+ ++ I E + + ++ +L +LQ+ +I+ L +L Sbjct: 534 IENKHSQQSNYEIEKLRQQNQQLIDELNEWKNRNKQLEGKLQQ---QIVMLNQAQNDLQA 590 Query: 1188 HDVVNQEQ------INQLKSKLEQLNTENDNL---LSTVAELRSSISSAVDQRGFEIAEL 1238 H +N++Q NQL+ K+++L + L L+ L + ++DQ + L Sbjct: 591 HQALNEKQQYALNESNQLRVKIKELLDQIQYLEMELNKKDNLIQDLQISLDQFSKQRDSL 650 Query: 1239 WKQHLAQREADFQKTEHELRV-QLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQN 1297 +++ +++ + E ++ +L+ ++++++ L + QE + E + + Sbjct: 651 IIIEKEKKDFEYRIIQLEKQLAELTMYKTQFQDLQFKYNNLGQEYESLRKDYELLRYKYD 710 Query: 1298 KLQDKEEHLRNLQEKYADVINQIEILRSEIED--EKVAFXXXXXXXXXXXXXXXXDLRTE 1355 ++ + +++++ ++ + +++E L+SEI+ K ++ E Sbjct: 711 EINN--QYIQSKKQINIQINSEVEALKSEIQTWIIKCKTYESEISFLRSTINDYQEIEQE 768 Query: 1356 NQSYKQMQEQ---SILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELK 1412 ++ KQ E + + E QL++S R+++ E ++ ++LE Sbjct: 769 SEMLKQELETWQIKFADADRERIQLRQS----IQEYEKFKFRISELEREISNYKYKLEST 824 Query: 1413 DSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANH 1472 + E + TI L Q+ +FE +++ EY+ + E+E + LR ++ Sbjct: 825 EKERDGARQQLTI-LQQQRVQFEQIKK---EYDSLVYKF-QEQERDNLSLRNEIENLRQQ 879 Query: 1473 YETMQKES------EIERVKLIEELNVKITESVSLNKQVAELN--KALEEEVAKTNEM-Q 1523 ++Q+ E E+ +L+ ++ E L +Q++ N K E + + EM + Sbjct: 880 LISLQQLKQQLILIEQEKSQLLYKIEEFDRERQLLKQQISSANNIKMESESLKREYEMLR 939 Query: 1524 TALENQEIEIVTLNDEITNLQNMV----RASSSKIQKHVSF--ASDTKQGRDEQLDNTMN 1577 LE+ + EI T+ ++T N R S Q +SF + KQG +QL +N Sbjct: 940 MKLESSDREISTMRQQLTLASNQKIEFDRLRSEYQQLRMSFEDSEREKQGLKQQLQIGIN 999 Query: 1578 -KELLDAVPRAELDL 1591 K L+ R E DL Sbjct: 1000 VKNELEQF-RKEYDL 1013 Score = 107 bits (256), Expect = 3e-21 Identities = 171/902 (18%), Positives = 381/902 (42%), Gaps = 76/902 (8%) Query: 476 NEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKL 535 N++ +Q QL+Q D++++ I++L+ EQ+ + ++ + N++ K Sbjct: 369 NKLRDLQMQLQQSEKDKMRNDQYVRKIDELQLQVEQLQRQLYDLTSKYNNLLSQYEQKKY 428 Query: 536 KLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIE 595 ++ Q+ + N S+ ++ K I+ L ++ L ++A+ + + L +Y + ++ Sbjct: 429 QIDQLNGQL-NVSQDNEKQK-IMNLERQIRELQDQLADTQRLRQQLHQMNENYSALQITF 486 Query: 596 SDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQV 655 + K++ E + L R + +L + ++ Q++ +Q D + +L I S Q Sbjct: 487 KNSQKQLSEADEL---RQELDALFQELEYYKQQDMKS-KQDLDRYKQQLIIIENKHSQQS 542 Query: 656 CSEIKSVHLEEQ--IDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNY 713 EI+ + + Q ID L+ K + L+ L DL+ +N+ Q Y Sbjct: 543 NYEIEKLRQQNQQLIDELNEWKNRNKQLEGKLQQQIVMLNQAQNDLQ--AHQALNEKQQY 600 Query: 714 -IQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELS 772 + E+ L K++++ ++I L ++N ++ Q +D ++RD I IE E Sbjct: 601 ALNESNQLRVKIKEL-LDQIQYLEMELNKKDNLIQDLQISLDQFSKQRDSLII-IEKEKK 658 Query: 773 KYKSRICRLEESIAVM---EDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLA- 828 ++ RI +LE+ +A + + + L+ K + LG + +K Y + DE+ N+ Sbjct: 659 DFEYRIIQLEKQLAELTMYKTQFQDLQFKYNNLGQEYESLRKDYELLRYKYDEINNQYIQ 718 Query: 829 ----VLMDHDRVVEKQLLEIE--------------------HENKELQKKNQILLEENQN 864 + + + VE EI+ ++ +E+++++++L +E + Sbjct: 719 SKKQINIQINSEVEALKSEIQTWIIKCKTYESEISFLRSTINDYQEIEQESEMLKQELET 778 Query: 865 LQISLSDMQQHYNALVEKAN-------RTDLAESESTKYQTQLRDLESNLKRITHEHQTL 917 QI +D + L + R E E + Y+ +L E + + T+ Sbjct: 779 WQIKFADADRERIQLRQSIQEYEKFKFRISELEREISNYKYKLESTEKE-RDGARQQLTI 837 Query: 918 IVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMN 977 + Q++ + E ++ E+++ + ++++ N IE + Q LQ+ K + + Sbjct: 838 LQQQRVQFEQIKKEYDSLVYK-FQEQERDNLSLRNEIENLRQQLISLQQLKQQLILIEQE 896 Query: 978 VEELNKMNLELIDKHVQ--KQQTQSPDY----TEQYINEINKLNALLKQKDEEIIALNQK 1031 +L +E D+ Q KQQ S + +E E L L+ D EI + Q+ Sbjct: 897 KSQL-LYKIEEFDRERQLLKQQISSANNIKMESESLKREYEMLRMKLESSDREISTMRQQ 955 Query: 1032 I---NNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLL-------DSKQHNEEL 1081 + +N ++ + + S+Y+ Q E+ E E Q + +QL + +Q +E Sbjct: 956 LTLASNQKIEFDRLRSEYQ----QLRMSFEDSEREKQGLKQQLQIGINVKNELEQFRKEY 1011 Query: 1082 QILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXX 1141 ++ + ++ KE + ++ ++ + G I IE +S N Sbjct: 1012 DLIRLKFEESEKEKNQLRIQYQSSQSNVNGYKIQ--IEQLSSQINQFQSQELVMKREIEM 1069 Query: 1142 LKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQ--EQINQL 1199 L +Q+ + + +++ Q+Q + + QE + L+ + ++ + E QL Sbjct: 1070 L-IQQIDVYKKDQINKQQQIQEYQFKYQEIMKEYENLQGKQKNIDVDALMYEIYELKKQL 1128 Query: 1200 KSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRV 1259 K +Q E + ++ S+ ++Q + E + L + Q + E Sbjct: 1129 AQKDKQYEYERQEINEQKFQMEKSVKIRLEQEIRILNEKFNSELNELRRQIQIEKQEKLK 1188 Query: 1260 QLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQ 1319 S KYEQ + +Q + + M ++ L+ + KE+ + ++++ + Q Sbjct: 1189 LESELRIKYEQQIMQLQQQIKPSVDVDALMYEIFELKKQAVTKEQVIEQMKKEQYQLRVQ 1248 Query: 1320 IE 1321 +E Sbjct: 1249 ME 1250 Score = 104 bits (249), Expect = 2e-20 Identities = 244/1285 (18%), Positives = 550/1285 (42%), Gaps = 125/1285 (9%) Query: 99 KQKEILMEKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNAL 158 +QK+++ +++ + SKR + +++ L D + +TI +N L Sbjct: 128 RQKQVI-DRLNFDLDKSKRDNEQLLQALNDIKQRGLSQEQSLLQDNQRMKSTIDSLNNDL 186 Query: 159 SVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQM 218 LQ ++ +++ I D + ++ + +N+A E + Q+ Sbjct: 187 RSLQQEIYRLKS-INDKSRYVQDESNRYQQENQANLARIRQLEMQIRDLMSKEESYQLQI 245 Query: 219 TKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSL-----EEANKLLEAARFEISLEHSK 273 T+ + KD+ +L + + + ++ ++++ R I+++ Sbjct: 246 TRAAQGTNTENQLLKDQIAQLNQQLHMMQKQYQKQLDDVRQDQDRMISEQRNTINIQIKD 305 Query: 274 LAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEH 333 Q +Q L KQ + + + ++ K L L + + Sbjct: 306 QLQRDQQKWMDEREALLHEIQLLKQQL---AQNELQVTRKRQL-------LEDEANKNQQ 355 Query: 334 LNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSET 393 ++ Q N +L+NKL + + + S K + RK +++ QL + Sbjct: 356 FIVEMEQANGQLQNKLRDLQMQLQQ-SEKDKMRNDQYVRK-----IDELQLQVEQLQRQL 409 Query: 394 LNQDTDKKINKNEIAKLEMVIQSLNKDL-VDKEYVISEKDTXXXXXXXXXXGKDTLIAQL 452 + + ++ + + I LN L V ++ +EK +D L Sbjct: 410 YDLTSKYNNLLSQYEQKKYQIDQLNGQLNVSQD---NEKQKIMNLERQIRELQDQLADTQ 466 Query: 453 QLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQI 512 +L Q H + + ++ + ++L+QEL+ +++ + +KS ++ Sbjct: 467 RLRQQLHQMNENYSALQITFKNSQKQLSEADELRQELDALFQELEYYKQ-QDMKSKQDLD 525 Query: 513 TQLNDEIDAANKNMIKVKSNHKL-KLKQM-QKTIDNFSKVSDSNKEIVRLTEELHHLSQK 570 I NK+ +SN+++ KL+Q Q+ ID ++ + NK++ L Q+ Sbjct: 526 RYKQQLIIIENKH--SQQSNYEIEKLRQQNQQLIDELNEWKNRNKQLEG------KLQQQ 577 Query: 571 VAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQEL 630 + L + + +LQ H + + ++ + ++++ L + +++ + + ++K +L+Q+L Sbjct: 578 IVMLNQAQNDLQAHQALNEKQQYALNESNQLRVKIKELLD-QIQYLEMELNKKDNLIQDL 636 Query: 631 HILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASK---KELALVIENLKL 687 I ++ + D L I + + D E + + LE+Q+ L+ K ++L NL Sbjct: 637 QISLDQFSKQRDSLIIIEKEKKD---FEYRIIQLEKQLAELTMYKTQFQDLQFKYNNLGQ 693 Query: 688 DKEQLYGTIKDLENDKEDIMNK-LQNYIQENMDLTDKLEKMSAEKISELL-AKINHEEQS 745 + E L + L ++I N+ +Q+ Q N+ + ++E + +E + ++ K E S Sbjct: 694 EYESLRKDYELLRYKYDEINNQYIQSKKQINIQINSEVEALKSEIQTWIIKCKTYESEIS 753 Query: 746 KIQTQFGIDAKI-QERDLYIENIESELSKY----KSRICRLEESIAVMEDRRYSLERKAD 800 +++ +I QE ++ + +E+ K+ + RI +L +SI E ++ + Sbjct: 754 FLRSTINDYQEIEQESEMLKQELETWQIKFADADRERI-QLRQSIQEYEKFKFRISELER 812 Query: 801 QLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLE 860 ++ +Y K E T +E + + ++ RV Q +I+ E L K Q Sbjct: 813 EISNY-----KYKLESTEKERDGARQQLTILQQQRV---QFEQIKKEYDSLVYKFQEQER 864 Query: 861 ENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQ 920 +N +L+ + +++Q +L + + L E E ++ ++ + + E Q L+ Q Sbjct: 865 DNLSLRNEIENLRQQLISLQQLKQQLILIEQEKSQLLYKIEEFD-------RERQ-LLKQ 916 Query: 921 KKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQL---QEYKNNIENLNMN 977 + ++++E ES R+ ++L K E + ++ + QL K + L Sbjct: 917 QISSANNIKMES----ESLKREYEMLRMKLESSDREISTMRQQLTLASNQKIEFDRLRSE 972 Query: 978 VEELNKMNLELIDKHVQ--KQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNA 1035 ++L +M+ E ++ Q KQQ Q + + + K L++ K EE ++ Sbjct: 973 YQQL-RMSFEDSEREKQGLKQQLQIGINVKNELEQFRKEYDLIRLKFEESEKEKNQLRIQ 1031 Query: 1036 QVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKEL 1095 S S V+ Y+ ++ Q ++++ N + + V K+ ++ +++ + ++Q ++ +++ Sbjct: 1032 YQSSQSNVNGYKIQIEQLSSQI-NQFQSQELVMKREIEMLI--QQIDVYKKDQINKQQQI 1088 Query: 1096 KETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERS 1155 +E + ++ + + E + + + DA + + + E + I E+ Sbjct: 1089 QEYQFKYQEIMKEYENL--QGKQKNIDVDALMYEIYELKKQLAQKDKQYEYERQEINEQK 1146 Query: 1156 VLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQIN-QLKSKLE-QLNTENDN- 1212 E+S K+ E QE +I+ E N+EL +++ Q QI Q K KLE +L + + Sbjct: 1147 FQMEKSVKIRLE-QEI--RILN-EKFNSEL--NELRRQIQIEKQEKLKLESELRIKYEQQ 1200 Query: 1213 LLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREA--DFQKTEHELRVQLSA------- 1263 ++ +++ S+ VD +EI EL KQ + + + +K +++LRVQ+ Sbjct: 1201 IMQLQQQIKPSVD--VDALMYEIFELKKQAVTKEQVIEQMKKEQYQLRVQMEQRYNEQKL 1258 Query: 1264 -FESKYEQLLD-----SVQSSTQEETNKIVTME--------QVTSLQNKLQDKEE---HL 1306 FES+ L+ S++S + + E Q+ ++ Q ++E HL Sbjct: 1259 QFESEIRMKLERELRISIESDLRYQIENEYNFESNIQDYVLQIEKWKSVCQMRDEEIAHL 1318 Query: 1307 RNLQEKYADVINQ----IEILRSEI 1327 R LQ+ + +NQ IE LR+++ Sbjct: 1319 RGLQQALKEKLNQYTSEIESLRTQL 1343 Score = 41.5 bits (93), Expect = 0.19 Identities = 95/501 (18%), Positives = 206/501 (41%), Gaps = 39/501 (7%) Query: 212 EDTKQQMTKMQE---NFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEIS 268 E+ +QQ+ +Q+ I +E EK +LL IE D L++ + +A I Sbjct: 874 ENLRQQLISLQQLKQQLILIE----QEKSQLLYKIEEFDRERQLLKQQ---ISSAN-NIK 925 Query: 269 LEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIE----EKGSLEIANMTEL 324 +E L +E E + +Q + + +K E + E L ++ Sbjct: 926 MESESLKREYEMLRMKLESSDREISTM-RQQLTLASNQKIEFDRLRSEYQQLRMSFEDSE 984 Query: 325 TKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKS 384 +K L + L I N+ + + K S +K I +S ++ + K Sbjct: 985 REKQGLKQQLQIGINVKNELEQFRKEYDLIRLKFEESEKEKNQLRIQYQSSQSNVNGYKI 1044 Query: 385 PWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISE---KDTXXXXXXXX 441 QLSS+ + + + K EI L I KD ++K+ I E K Sbjct: 1045 QIEQLSSQINQFQSQELVMKREIEMLIQQIDVYKKDQINKQQQIQEYQFKYQEIMKEYEN 1104 Query: 442 XXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTE-DVNEIAKVQEQLKQELNDEIKDVNVKD 500 GK I L ++ + L E + EI + + Q+++ + ++ ++ Sbjct: 1105 LQGKQKNIDVDALMYEIYELKKQLAQKDKQYEYERQEINEQKFQMEKSVKIRLEQ-EIRI 1163 Query: 501 LIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLK----LKQMQKTIDNFSKVSDSNKE 556 L EK S ++ +L +I + +K++S ++K + Q+Q+ I V E Sbjct: 1164 LNEKFNS---ELNELRRQIQIEKQEKLKLESELRIKYEQQIMQLQQQIKPSVDVDALMYE 1220 Query: 557 IVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAI 616 I L ++ Q + ++++E+ L++ + + + ++ ++ I M+ E R I Sbjct: 1221 IFELKKQAVTKEQVIEQMKKEQYQLRVQMEQRYNEQKLQ---FESEIRMKLERELR---I 1274 Query: 617 SLLESQKFDLVQELHILQQKYDEV--EDKLADISQLQSDQVCSEIKSVH--LEEQIDALS 672 S+ ++ + E + D V +K + Q++ +++ + ++ + L+E+++ + Sbjct: 1275 SIESDLRYQIENEYNFESNIQDYVLQIEKWKSVCQMRDEEI-AHLRGLQQALKEKLNQYT 1333 Query: 673 ASKKELALVIENLKLDKEQLY 693 + + L + ++ D+ +Y Sbjct: 1334 SEIESLRTQLALMQGDRRTVY 1354 >UniRef50_A0CJD5 Cluster: Chromosome undetermined scaffold_2, whole genome shotgun sequence; n=2; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_2, whole genome shotgun sequence - Paramecium tetraurelia Length = 986 Score = 126 bits (304), Expect = 5e-27 Identities = 172/862 (19%), Positives = 375/862 (43%), Gaps = 63/862 (7%) Query: 451 QLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEE 510 QLQL+++ G + + E++ + AK+ + L++++ + D +K+L E LK + Sbjct: 150 QLQLQNKL-FGGKAPEEISKELEELRKKAKILDDLQKKIGAKGPDELLKEL-ENLKKKAQ 207 Query: 511 QITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQK 570 Q +N +++ N S+ + +L+++++ D F ++S + +EL L +K Sbjct: 208 QFDDINKKLNGKNF------SDLEKELEKLRQKADKFDEISKQFSNPSDIQKELDQLKKK 261 Query: 571 VAELEEEKGNLQLHLVDYDSGRMIES-DVYKKMIEMENLAETRLK-AISLLESQKFDLVQ 628 AEL++ L+ L + + ++++S D KK ++ ++ LK +S L+ + Sbjct: 262 AAELDK----LKTQLNNQNPDQLLKSLDENKKQLQSKDREIGDLKRLLSELQQNQGSYDD 317 Query: 629 ELHILQQKYDEVEDKLADISQ-LQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKL 687 ++ +LQQK DE+E+K+ ++Q L ++ + K L + S+ LA + L+ Sbjct: 318 QIRLLQQKIDELEEKVVGLAQELSRYKMLLKAKDDELNKLQLLFRDSETRLAQMNNELQR 377 Query: 688 DKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLT-DKLEKMSAEKISELLAKINHEEQSK 746 K L DL+ + D+ + + DL+ + E + ++ S+ L + N E Sbjct: 378 SKNDLQRAQGDLQRAQGDLQKAQGDLRKAQTDLSRSQQENQNLKQQSDDLRRQNQE---- 433 Query: 747 IQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYL 806 QE + +++E++ ++ ++ +++ + ++D + L K L + L Sbjct: 434 ---------LAQENNNLQQDLENQ-TQNLGQLDEIKDQLNELQDEKNQLNDKVSDLQNNL 483 Query: 807 QEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQ 866 +EKQ+ + + ++ EL + L + D +E +LLE++H L+ Q ++NQ L Sbjct: 484 KEKQRLFDQ---KQKELEDALKRVKD----LEAKLLEMDHYIDTLEDDLQKFEKDNQQLN 536 Query: 867 ISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIE 926 Q L D +++ + Q +L L++NL ++ + Q + Q K E+ Sbjct: 537 REAGQKQLADRELERLRGLLDQMKNQYDQQQKELGKLKNNLDQM-RDLQDELAQAKSEL- 594 Query: 927 DLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNL 986 D Q + + K+ + + ++ + + QLQ+ NN++ + + N Sbjct: 595 DRANSVIAQQQDELAQKENEISQLVREVQNLEESNNQLQDQNNNLQQTLQEQQAVTNGNQ 654 Query: 987 ELIDK--HVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVS 1044 E + K + + + E NE + + LKQ D I L M+ + Sbjct: 655 EELTKLRRIAEDYKEKIRQLELKFNEYSNMEERLKQSDHRIAVL-----------MTEIE 703 Query: 1045 DYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFE- 1103 S + Q T++ E+ +++ R+ LL+ +Q + + V + I E++ K E Sbjct: 704 RLNSLVKQITSETEDWKQKHSRIELALLEYRQIEKTNRDAVNKNQQFINEIERLKKLLEA 763 Query: 1104 MNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQ------EEEEFIQERSVL 1157 +I + + +E N + +Q E E + Sbjct: 764 KHIELLQTIERCELLESQQQTLMNQVQDALKKADTGDEILLQYLLIAAENERLSGILQPM 823 Query: 1158 QEQSAKLNTELQECYTKIIQLE--TLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLS 1215 QE+ +L T+++E K +L+ TL +L ++ + ++ I + ++K+ L+ E L + Sbjct: 824 QEKFNQLTTQVKEMTVKYTELQNKTLGIDLDEYERL-KKLIIEYENKIAMLSLEIQRLKA 882 Query: 1216 TVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSV 1275 L + S I + + Q D +L ++ ++ + L + Sbjct: 883 KTNILDKNGQSGNFGSNNNINIQYNSSMFQSNEDLSNKITDLLCLVAMMSAELDVLRSNN 942 Query: 1276 QSSTQEE-TNKIVTMEQVTSLQ 1296 + Q++ N+ +VT++Q Sbjct: 943 EKQVQQQLVNQYRQNTEVTNIQ 964 Score = 111 bits (267), Expect = 2e-22 Identities = 193/888 (21%), Positives = 392/888 (44%), Gaps = 101/888 (11%) Query: 474 DVNEIAKVQEQLKQELNDEIK--------DVNVKDLIEKLKSAEEQITQLNDEIDAANKN 525 +V + + QLKQE+ + I ++ ++DL+EKLK+ ++ ++E + Sbjct: 59 EVERLVRENTQLKQEIQNFIDSGLDRVNYEMQIRDLMEKLKNQTFEVNSYSEERERL-VI 117 Query: 526 MIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEI-VRLTEELH--HLSQKVA-ELEEEKGNL 581 +I+ + +L++ K D + S + E+ ++L +L ++++ ELEE + Sbjct: 118 IIRELEDEIRRLEEQLKDYDPNWRKSQRDLELQLQLQNKLFGGKAPEEISKELEELRKKA 177 Query: 582 QLHLVDYDS--GRMIESDVYKKMIEMENLAETRLKAISLLESQKF-DLVQELHILQQK-- 636 ++ L D G ++ K++ ++ A+ L + F DL +EL L+QK Sbjct: 178 KI-LDDLQKKIGAKGPDELLKELENLKKKAQQFDDINKKLNGKNFSDLEKELEKLRQKAD 236 Query: 637 -YDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGT 695 +DE+ + ++ S +Q + + K+ L++ L+ + L ++L +K+QL Sbjct: 237 KFDEISKQFSNPSDIQKELDQLKKKAAELDKLKTQLNNQNPDQLL--KSLDENKKQLQSK 294 Query: 696 IKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDA 755 +++ + + +L + +Q+N D ++ +KI EL K+ G+ Sbjct: 295 DREIGD-----LKRLLSELQQNQGSYDDQIRLLQQKIDELEEKV-----------VGLAQ 338 Query: 756 KIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSE 815 ++ + ++ + EL+K + E +A M + L+R + L + Q+A + Sbjct: 339 ELSRYKMLLKAKDDELNKLQLLFRDSETRLAQMNNE---LQRSKNDLQRAQGDLQRAQGD 395 Query: 816 YTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQH 875 + +L L + E Q ++ ++ +L+++NQ L +EN NLQ L + Q+ Sbjct: 396 LQKAQGDLRKAQTDLSRSQQ--ENQ--NLKQQSDDLRRQNQELAQENNNLQQDLENQTQN 451 Query: 876 YNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQ 935 L E ++ + + E + ++ DL++NLK E Q L QK+KE+ED Sbjct: 452 LGQLDEIKDQLNELQDEKNQLNDKVSDLQNNLK----EKQRLFDQKQKELED-------- 499 Query: 936 IESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQK 995 A++ K L K + Y+ LE LQ+++ + + LN + + EL + ++ Sbjct: 500 ---ALKRVKDLEAKLLEMDHYIDTLEDDLQKFEKDNQQLNREAGQKQLADREL--ERLRG 554 Query: 996 QQTQSPDYTEQYINEINKL-NALLKQKD--EEIIALNQKINNAQVSYMSMVSDYESKLAQ 1052 Q + +Q E+ KL N L + +D +E+ +++ A S+++ + +LAQ Sbjct: 555 LLDQMKNQYDQQQKELGKLKNNLDQMRDLQDELAQAKSELDRAN----SVIAQQQDELAQ 610 Query: 1053 FTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGM 1112 ++ + E+Q + + + N LQ ++EQ + + +LT I + Sbjct: 611 KENEISQLVREVQNLEESNNQLQDQNNNLQQTLQEQ-QAVTNGNQEELTKLRRIAEDYKE 669 Query: 1113 IISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECY 1172 I +E ++ +N++ L + E V Q S + + + Sbjct: 670 KIRQ-LELKFNEYSNMEERLKQSDHRIAVLMTEIER---LNSLVKQITSETEDWKQKHSR 725 Query: 1173 TKIIQLETLNTELTGHDVVNQEQ--INQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQ 1230 ++ LE E T D VN+ Q IN+++ + L ++ LL T+ Sbjct: 726 IELALLEYRQIEKTNRDAVNKNQQFINEIERLKKLLEAKHIELLQTIERC---------- 775 Query: 1231 RGFEIAELWKQHLAQREADFQK---TEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIV 1287 E+ E +Q L + D K T E+ +Q ++ E+ L + QE+ N++ Sbjct: 776 ---ELLESQQQTLMNQVQDALKKADTGDEILLQYLLIAAENER-LSGILQPMQEKFNQLT 831 Query: 1288 TM-----EQVTSLQNKLQ--DKEEHLRNLQEKYADVINQIEILRSEIE 1328 T + T LQNK D +E+ R L++ + N+I +L EI+ Sbjct: 832 TQVKEMTVKYTELQNKTLGIDLDEYER-LKKLIIEYENKIAMLSLEIQ 878 Score = 89.8 bits (213), Expect = 5e-16 Identities = 193/999 (19%), Positives = 427/999 (42%), Gaps = 104/999 (10%) Query: 575 EEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELH--- 631 + ++ ++ L+ + R++ + K E++N ++ L ++ E Q DL+++L Sbjct: 45 QNQELDIACFLMAVEVERLVRENTQLKQ-EIQNFIDSGLDRVNY-EMQIRDLMEKLKNQT 102 Query: 632 ILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQ 691 Y E ++L I + D++ LEEQ+ + ++ +E + + Sbjct: 103 FEVNSYSEERERLVIIIRELEDEIR------RLEEQLKDYDPNWRKSQRDLELQLQLQNK 156 Query: 692 LYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQF 751 L+G E+I +L+ ++ L D +K+ A+ ELL ++ + ++ K Q Sbjct: 157 LFGG-----KAPEEISKELEELRKKAKILDDLQKKIGAKGPDELLKELENLKK-KAQQFD 210 Query: 752 GIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQK 811 I+ K+ ++ ++E EL K + + + +E I+ ++++ DQL E K Sbjct: 211 DINKKLNGKNF--SDLEKELEKLRQKADKFDE-ISKQFSNPSDIQKELDQLKKKAAELDK 267 Query: 812 AYSEYTIQE-DELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLS 870 ++ Q D+L+ L + ++++ +++ ELQ+ ++ + LQ + Sbjct: 268 LKTQLNNQNPDQLLKSLDENKKQLQSKDREIGDLKRLLSELQQNQGSYDDQIRLLQQKID 327 Query: 871 DMQQHYNALVEKANRTDLA----ESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIE 926 ++++ L ++ +R + + E K Q RD E+ L ++ +E Q ++ Sbjct: 328 ELEEKVVGLAQELSRYKMLLKAKDDELNKLQLLFRDSETRLAQMNNELQRSKNDLQRAQG 387 Query: 927 DLEIEFNTQIESAIRDKKV----LNEKYEKNIEYVTQ---LEAQLQEYKNNIENLNMNVE 979 DL+ ++ A D + L+ ++N Q L Q QE NL ++E Sbjct: 388 DLQ-RAQGDLQKAQGDLRKAQTDLSRSQQENQNLKQQSDDLRRQNQELAQENNNLQQDLE 446 Query: 980 ELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSY 1039 + NL +D+ ++ Q + D Q ++++ L LK+K +++ +A Sbjct: 447 NQTQ-NLGQLDE-IKDQLNELQDEKNQLNDKVSDLQNNLKEKQRLFDQKQKELEDA---- 500 Query: 1040 MSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETK 1099 + V D E+KL + ++ +E+++Q+ K + + Q+ RE + L + K Sbjct: 501 LKRVKDLEAKLLEMDHYIDTLEDDLQKFEKDNQQLNREAGQKQLADRELERLRGLLDQMK 560 Query: 1100 LTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVL-- 1157 ++ K G + + ++ M D + + Q + E + SV+ Sbjct: 561 NQYDQQ-QKELGKL-KNNLDQMRDLQDEL---------------AQAKSELDRANSVIAQ 603 Query: 1158 -QEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLST 1216 Q++ A+ E+ + ++ LE N +L Q+Q N L+ L++ + Sbjct: 604 QQDELAQKENEISQLVREVQNLEESNNQL-------QDQNNNLQQTLQEQQAVTNGNQEE 656 Query: 1217 VAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQ 1276 + +LR I+ ++ ++ EL + E ++++H + V ++ E + L+ + Sbjct: 657 LTKLRR-IAEDYKEKIRQL-ELKFNEYSNMEERLKQSDHRIAVLMTEIE-RLNSLVKQIT 713 Query: 1277 SSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXX 1336 S T++ K +E + L+ + +K R+ K IN+IE L+ +E + + Sbjct: 714 SETEDWKQKHSRIE-LALLEYRQIEKTN--RDAVNKNQQFINEIERLKKLLEAKHIELLQ 770 Query: 1337 XXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVN 1396 E + Q+Q+++N ++A K + N Sbjct: 771 TI----------------ERCELLESQQQTLMN-QVQDALKKADTGDEILLQYLLIAAEN 813 Query: 1397 DAEAKVLE-LTHQLELKDSEIYQKTHEYTI----TLTQRNDEFENVRQQLVEYEKRIEDL 1451 + + +L+ + + +++ + T +YT TL DE+E +++ ++EYE +I L Sbjct: 814 ERLSGILQPMQEKFNQLTTQVKEMTVKYTELQNKTLGIDLDEYERLKKLIIEYENKIAML 873 Query: 1452 TYEKESELAILRL--KMHENAN--HYETMQKESEIERVKLIEELNVKITESVSLNKQVAE 1507 + E + A + K ++ N + + + E+L+ KIT+ + L VA Sbjct: 874 SLEIQRLKAKTNILDKNGQSGNFGSNNNINIQYNSSMFQSNEDLSNKITDLLCL---VAM 930 Query: 1508 LNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNM 1546 ++ L + + NE Q ++ Q + N E+TN+Q + Sbjct: 931 MSAEL-DVLRSNNEKQ--VQQQLVNQYRQNTEVTNIQTV 966 Score = 89.8 bits (213), Expect = 5e-16 Identities = 153/771 (19%), Positives = 337/771 (43%), Gaps = 76/771 (9%) Query: 321 MTELTKKIELLEHLNCQIRQTNK-ELENKLATMGTESKAVSSPSKK--GSPLISRKSGRN 377 + EL KK ++L+ L +I EL +L + +++ +KK G + Sbjct: 170 LEELRKKAKILDDLQKKIGAKGPDELLKELENLKKKAQQFDDINKKLNGKNFSDLEKELE 229 Query: 378 TASKMKSPWSQLSSETLN-QDTDKKIN--KNEIAKLEMVIQSLNKDLVDKEYVISEKDTX 434 + + ++S + N D K+++ K + A+L+ + LN D+ +++ Sbjct: 230 KLRQKADKFDEISKQFSNPSDIQKELDQLKKKAAELDKLKTQLNNQNPDQLLKSLDENKK 289 Query: 435 XXXXXXXXXGK-DTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEI 493 G L+++LQ + + L+ + + + QE + ++ + Sbjct: 290 QLQSKDREIGDLKRLLSELQQNQGSYDDQIRLLQQKIDELEEKVVGLAQELSRYKMLLKA 349 Query: 494 KDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSK---- 549 KD + L + +E ++ Q+N+E+ + ++ + + + + +QK + K Sbjct: 350 KDDELNKLQLLFRDSETRLAQMNNELQRSKNDLQRAQGDLQRAQGDLQKAQGDLRKAQTD 409 Query: 550 VSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLA 609 +S S +E L ++ L ++ EL +E NLQ L + ++ ++ E+++ Sbjct: 410 LSRSQQENQNLKQQSDDLRRQNQELAQENNNLQQDLENQTQNLGQLDEIKDQLNELQDEK 469 Query: 610 ETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQID 669 +S L++ +L ++ + QK E+ED L + L++ + + LE+ + Sbjct: 470 NQLNDKVSDLQN---NLKEKQRLFDQKQKELEDALKRVKDLEAKLLEMDHYIDTLEDDLQ 526 Query: 670 ALSASKKELALVIENLKL---DKEQLYGTIKDLEN---DKEDIMNKLQNYIQENMDLTDK 723 ++L +L + E+L G + ++N ++ + KL+N + + DL D+ Sbjct: 527 KFEKDNQQLNREAGQKQLADRELERLRGLLDQMKNQYDQQQKELGKLKNNLDQMRDLQDE 586 Query: 724 LEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICR-LE 782 L + +E + + I ++ Q + I ++E +E ++L + + + L+ Sbjct: 587 LAQAKSE-LDRANSVIAQQQDELAQKENEISQLVREVQ-NLEESNNQLQDQNNNLQQTLQ 644 Query: 783 ESIAVM---EDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELV---NRLAVLM----- 831 E AV ++ L R A+ +++ + ++EY+ E+ L +R+AVLM Sbjct: 645 EQQAVTNGNQEELTKLRRIAEDYKEKIRQLELKFNEYSNMEERLKQSDHRIAVLMTEIER 704 Query: 832 -----------------DHDRVVEKQLLE---IEHENKELQKKNQILLEENQNLQISLSD 871 H R +E LLE IE N++ KNQ + E + L+ L Sbjct: 705 LNSLVKQITSETEDWKQKHSR-IELALLEYRQIEKTNRDAVNKNQQFINEIERLKKLL-- 761 Query: 872 MQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRI-THEH---QTLIVQKKKE--- 924 + + L++ R +L ES+ QT + ++ LK+ T + Q L++ + E Sbjct: 762 -EAKHIELLQTIERCELLESQQ---QTLMNQVQDALKKADTGDEILLQYLLIAAENERLS 817 Query: 925 --IEDLEIEFN---TQI-ESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNV 978 ++ ++ +FN TQ+ E ++ ++ N+ +++ +L+ + EY+N I L++ + Sbjct: 818 GILQPMQEKFNQLTTQVKEMTVKYTELQNKTLGIDLDEYERLKKLIIEYENKIAMLSLEI 877 Query: 979 EELNKMNLELIDKHVQKQQTQSPDYTE-QYINEINKLNALLKQKDEEIIAL 1028 + L K ++DK+ Q S + QY + + + N L K +++ L Sbjct: 878 QRL-KAKTNILDKNGQSGNFGSNNNINIQYNSSMFQSNEDLSNKITDLLCL 927 Score = 43.6 bits (98), Expect = 0.046 Identities = 100/527 (18%), Positives = 203/527 (38%), Gaps = 33/527 (6%) Query: 140 QLGD-VTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXX 198 QL D V+ L N +KEK Q +++ + DL+ K+ E D I+ T Sbjct: 471 QLNDKVSDLQNNLKEKQRLFDQKQKELEDALKRVKDLEAKLLEMDHYID-----TLEDDL 525 Query: 199 XXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANK 258 KQ + E + + K++ + K++ + + + Sbjct: 526 QKFEKDNQQLNREAGQKQLADRELERLRGLLDQMKNQYDQQQKELGKLKNNLDQMRDLQD 585 Query: 259 LLEAARFEISLEHSKLAQ---ELEQXXXXXXXXXXXXXXLAK---QSIEPSCEEKTEIEE 312 L A+ E+ +S +AQ EL Q L + Q + + + ++E Sbjct: 586 ELAQAKSELDRANSVIAQQQDELAQKENEISQLVREVQNLEESNNQLQDQNNNLQQTLQE 645 Query: 313 KGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISR 372 + ++ N ELTK + E +IRQ LE K + + + + L++ Sbjct: 646 QQAVTNGNQEELTKLRRIAEDYKEKIRQ----LELKFNEYSNMEERLKQSDHRIAVLMTE 701 Query: 373 KSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLE-MVIQSLNKDLVDK-EYVISE 430 N+ K Q++SET +D +K ++ E+A LE I+ N+D V+K + I+E Sbjct: 702 IERLNSLVK------QITSET--EDWKQKHSRIELALLEYRQIEKTNRDAVNKNQQFINE 753 Query: 431 KDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELN 490 + I + +L Q + + D + +Q L N Sbjct: 754 IERLKKLLEAKHIELLQTIERCELLESQQQTLMNQVQDALKKADTGDEILLQYLLIAAEN 813 Query: 491 DEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKV 550 + + + ++ + EK Q+ ++ + + + + +LK++ I+ +K+ Sbjct: 814 ERLSGI-LQPMQEKFNQLTTQVKEMTVKYTELQNKTLGIDLDEYERLKKL--IIEYENKI 870 Query: 551 SDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAE 610 + + EI RL + + L K + N +++ S D+ K+ ++ L Sbjct: 871 AMLSLEIQRLKAKTNIL-DKNGQSGNFGSNNNINIQYNSSMFQSNEDLSNKITDLLCLVA 929 Query: 611 TRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCS 657 + +L S VQ+ + Q + + ++ +I +QS + S Sbjct: 930 MMSAELDVLRSNNEKQVQQQLVNQYRQN---TEVTNIQTVQSVETTS 973 >UniRef50_O61308 Cluster: 227 kDa spindle- and centromere-associated protein; n=1; Parascaris univalens|Rep: 227 kDa spindle- and centromere-associated protein - Parascaris univalens Length = 1955 Score = 126 bits (304), Expect = 5e-27 Identities = 253/1333 (18%), Positives = 563/1333 (42%), Gaps = 116/1333 (8%) Query: 212 EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271 EDTK + K EN +E L E+ I+ LE K + R EIS E Sbjct: 570 EDTKLDLLKDLENQRTRYDAVTNELDTLQTTFETSTKNIAQLEANIKEINLMRDEISKEK 629 Query: 272 SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELL 331 LAQ+L + ++ I+ SC +E EK L+I E +++ L Sbjct: 630 DSLAQKL-----ADVTHKLEIETVRREDIQRSCVGHSEDVEKQRLQI---IEYEREVMAL 681 Query: 332 EHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPL---ISRKSGRNTASKMKSPWS- 387 LN ++ K + K+ ++ +V + K + L + ++ +SK K+ Sbjct: 682 RRLNDELDTNVKTGQAKVTSLENSIISVQTEVTKLTTLNDKLQKEKQSIMSSKQKADTDV 741 Query: 388 QLSSE---TLNQDTDKKINKNE-IAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXX 443 L E L Q+ DK +N+ + + E + + + K+ + +++ E+D Sbjct: 742 DLLKEKLRKLEQECDKLKEENKALHEDEQIARQMCKEEASRIHLL-ERDLKDAMTEVEEL 800 Query: 444 GKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIE 503 K + ++ E+ + +E + ++T D +EIA E +V VK+L E Sbjct: 801 KKQ--LQKMDEENSERLESVLRTKISSDTVDTSEIA------------EYTEVKVKELRE 846 Query: 504 KLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEE 563 K K+ E++ D+++ +++ + + ++ + Q+T N K+ + E RL E Sbjct: 847 KYKADLERLQSNKDDLE-RRVQILEDELAERQRIVERQRTEMNDLKL-EYQLESDRLRAE 904 Query: 564 LHHLSQKV-AELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQ 622 + + K +E+E+E+ D DS ++ ++ K+ ME + E E++ Sbjct: 905 MATVELKYQSEVEDERDQRSR---DADSWKVTSEELRSKISFMEKMLE---------EAK 952 Query: 623 KFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVI 682 + V L+++ E E+K DI +S ++ +EI+ + + + D + KK++ + Sbjct: 953 HRETV-----LREEATEWEEK-HDIISNESLKLRNEIERIRSDAEED-IQKWKKDVHMAQ 1005 Query: 683 ENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSA--EKISELLAKIN 740 LK + E++ T++ D + L I E T K+ ++++ ++ E LA + Sbjct: 1006 NELK-NLERVCETLRSQLTAANDRVASLNTTINEQ---TSKIRELNSHEHRLEEDLAD-S 1060 Query: 741 HEEQSKIQTQFG-IDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKA 799 S I+ G +++ + + ++SE K K+ I L+ I + + + S E + Sbjct: 1061 RATSSAIENDLGNATGRLRSSEEHNAILQSENRKSKTEIEALKHQIDTIMNTKESCESEV 1120 Query: 800 DQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDH-DRVVEKQLLEIEHENKELQKKNQIL 858 ++ L++K + T +++E + +L + DH +R ++ E++ KE++K + Sbjct: 1121 ER----LKKKIVQTTTITKEQNEKIEKLRIEHDHLERDYREKTKEVD-RLKEVEKTFE-- 1173 Query: 859 LEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHE-HQTL 917 L+ N+ Q ++ + L+ + E+ K +++ ++ L+ + E H+ L Sbjct: 1174 LKVNRARQ----ELDEFSKKLIVTETERNAISGEAQKLDKEVQLVKEQLQYKSDEFHKAL 1229 Query: 918 --IVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLN 975 + + E+ + Q+E+ + L + E + + + L+ QEY N + Sbjct: 1230 DELANAHRISEEGRVNAIHQLEARRFEIDDLKSRLENSEQRLATLQ---QEYVNADKERG 1286 Query: 976 MNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNA 1035 + + + + V ++ Q ++++ A+ ++++E +LN+ N Sbjct: 1287 ALNDAMRRFQATISRSVVAEEHVDVSTIETQMQKLMSRIEAIERERNEYRDSLNRLKNRC 1346 Query: 1036 QVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKEL 1095 SY S V E+ F ++ + E+E ++V +L K+ + + ++++D++ + L Sbjct: 1347 STSY-SSVDRQETVYRTFEERVISAEDERRKVELKLSSMKEMLKSQEEKLKQRDEERRNL 1405 Query: 1096 KETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERS 1155 K +TFE+ E + I ++D V L+ + +E++ R Sbjct: 1406 KSNIVTFEL-----EARAKDAQIRHLNDLLKRVQAELENSQNDNRALR-ERQEQYETNRI 1459 Query: 1156 VLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLS 1215 L++ +L T+ E K + + TE + + +L S+L+ T+N +L Sbjct: 1460 HLEQ---RLPTDEGEPRVKAL-MAAFATERQS----LSDSLKKLASQLQISETKNADLRD 1511 Query: 1216 TVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSV 1275 L+ + A + E +++L + + + + +LR QL +S D Sbjct: 1512 DAERLKRDLLKAE-----RVEEDLRRNLVE-QTEIMRENQQLRSQLGVAQS------DLA 1559 Query: 1276 QSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIE---ILRSEIEDEKV 1332 +S +++ + ++ +++ +L+D ++HL + + A++ Q++ +S + D + Sbjct: 1560 NASGRKQQLE----GELAAVRAELRDHKQHLHDAISRIAELQRQLQDANAEKSRLTDRII 1615 Query: 1333 AFXXXXXXXXXXXXXXXXDLRTENQSYKQM-QEQSILNINEENAQLKKSSXXXXXXXXXX 1391 L T K + E + + +K Sbjct: 1616 GLEKTIGTLRNTETELRAQLSTAADERKALNSELEEMRRRIVQMESEKKDVDNQLEEVNK 1675 Query: 1392 XXRVNDAEAKVLEL-THQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIED 1450 + + ++LE H EL SE + +L E + + + + +++I Sbjct: 1676 ARIIMTKKIEILETEKHSAELVISETASQREAIERSLNALERENKELYKNCAQLQQQIAQ 1735 Query: 1451 LTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELN-VKITESVSLNKQVAELN 1509 L + L L K E+ + K +++ +++E + + + L Q++ + Sbjct: 1736 LEMDNGERLIALTTKQKEDHEKFVAAVKAEKVQVERIVENRDRAQKSRIRQLENQLSMMR 1795 Query: 1510 KALEEEVAKTNEM 1522 + L+ E A++++M Sbjct: 1796 EQLDNERARSHQM 1808 Score = 98.7 bits (235), Expect = 1e-18 Identities = 206/1170 (17%), Positives = 478/1170 (40%), Gaps = 110/1170 (9%) Query: 495 DVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSN 554 D ++ + KLK+++ Q+ +L ++ + + +S+ +L + + I + V D+N Sbjct: 393 DSEMQHIQRKLKNSDTQVCELTTRLEGTEE--ARRRSDKQLVDAKREINIQQRA-VDDAN 449 Query: 555 KEIVRLTEELHHL-SQKVA------ELEEE--KGNLQLHLVDYDSGRMI--ESDVYKKMI 603 +E+ R+ + LH + S+K+ +LEEE + LQ+ D R + E ++ K+++ Sbjct: 450 RELRRVEDRLHIMESEKIVAENARQQLEEEVRRLTLQVDQSKADGERRVVEEGEIQKRIV 509 Query: 604 EME--NLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKL-ADISQLQSDQVC-SEI 659 E E ++ + ++ + + L +L +++ VE + + + +L+ + + Sbjct: 510 EDEYRSMISELTRRMNAFQDENKRLKNDLGCTKERLKNVEFEYNSTVRKLEDKDIALKHL 569 Query: 660 KSVHLE---------EQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKL 710 + L+ + DA++ L E + QL IK++ +++I + Sbjct: 570 EDTKLDLLKDLENQRTRYDAVTNELDTLQTTFETSTKNIAQLEANIKEINLMRDEISKEK 629 Query: 711 QNYIQENMDLTDKLEKMSAEKISELLAKINH-EEQSKIQTQF---------------GID 754 + Q+ D+T KLE + + + + H E+ K + Q +D Sbjct: 630 DSLAQKLADVTHKLEIETVRREDIQRSCVGHSEDVEKQRLQIIEYEREVMALRRLNDELD 689 Query: 755 AKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSL---ERKADQLGSYLQEKQK 811 ++ + ++E+ + ++ + +L ++ + S+ ++KAD L+EK + Sbjct: 690 TNVKTGQAKVTSLENSIISVQTEVTKLTTLNDKLQKEKQSIMSSKQKADTDVDLLKEKLR 749 Query: 812 AYSE---------YTIQEDELVNRLAVLMDHDRV--VEKQLLEIEHENKELQKKNQILLE 860 + + EDE + R + R+ +E+ L + E +EL+K+ Q + E Sbjct: 750 KLEQECDKLKEENKALHEDEQIARQMCKEEASRIHLLERDLKDAMTEVEELKKQLQKMDE 809 Query: 861 EN-QNLQISL-SDMQQHYNALVEKANRTDLAESE-STKYQTQLRDLESNLKRITHEHQTL 917 EN + L+ L + + E A T++ E KY+ L L+SN + Q L Sbjct: 810 ENSERLESVLRTKISSDTVDTSEIAEYTEVKVKELREKYKADLERLQSNKDDLERRVQIL 869 Query: 918 ---IVQKKKEIEDLEIEFN-TQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIEN 973 + ++++ +E E N ++E + ++ E ++Y +++E + + + ++ Sbjct: 870 EDELAERQRIVERQRTEMNDLKLEYQLESDRLRAEMATVELKYQSEVEDERDQRSRDADS 929 Query: 974 LNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKIN 1033 + EEL + + ++K +++ + + E+ K + + E + L +I Sbjct: 930 WKVTSEEL-RSKISFMEKMLEEAKHRETVLREEATEWEEKHDII----SNESLKLRNEIE 984 Query: 1034 NAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIK 1093 + + ++ + +L+N+E + + QL + L + EQ +I+ Sbjct: 985 RIRSDAEEDIQKWKKDVHMAQNELKNLERVCETLRSQLTAANDRVASLNTTINEQTSKIR 1044 Query: 1094 ELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQE 1153 EL + E ++ + SS IE +D N L+ + + + Sbjct: 1045 ELNSHEHRLEEDL--ADSRATSSAIE---NDLGNATGRLRSSEEHNAILQSENRKSKTEI 1099 Query: 1154 RSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLK---SKLEQLNTEN 1210 ++ + +NT+ + C +++ +L+ + T E+I +L+ LE+ E Sbjct: 1100 EALKHQIDTIMNTK-ESCESEVERLKKKIVQTTTITKEQNEKIEKLRIEHDHLERDYREK 1158 Query: 1211 DNLLSTVAELRSSISSAVDQRGFEIAELWKQHL------------AQR-EADFQKTEHEL 1257 + + E+ + V++ E+ E K+ + AQ+ + + Q + +L Sbjct: 1159 TKEVDRLKEVEKTFELKVNRARQELDEFSKKLIVTETERNAISGEAQKLDKEVQLVKEQL 1218 Query: 1258 RVQLSAFESKYEQLLDSVQSSTQEETNKIVTME----QVTSLQNKLQDKEEHLRNLQEKY 1313 + + F ++L ++ + S + N I +E ++ L+++L++ E+ L LQ++Y Sbjct: 1219 QYKSDEFHKALDELANAHRISEEGRVNAIHQLEARRFEIDDLKSRLENSEQRLATLQQEY 1278 Query: 1314 ADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEE 1373 + + L + + + S + E+ + Sbjct: 1279 VNADKERGALNDAMRRFQATISRSVVAEEHVDVSTIETQMQKLMSRIEAIERERNEYRDS 1338 Query: 1374 NAQLKKSSXXXXXXXXXXXXRVNDAEAKVL---ELTHQLELKDSEIYQKTHEYTITLTQR 1430 +LK E +V+ + ++ELK S + + L QR Sbjct: 1339 LNRLKNRCSTSYSSVDRQETVYRTFEERVISAEDERRKVELKLSSMKEMLKSQEEKLKQR 1398 Query: 1431 NDEFENVRQQLV--EYEKRIEDLTYEKESEL---AILRLKMHENANH-YETMQKESEIER 1484 ++E N++ +V E E R +D ++L L+ +N N Q++ E R Sbjct: 1399 DEERRNLKSNIVTFELEARAKDAQIRHLNDLLKRVQAELENSQNDNRALRERQEQYETNR 1458 Query: 1485 VKLIEELNVKITES--VSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITN 1542 + L + L E +L A ++L + + K + + L+ E + L D+ Sbjct: 1459 IHLEQRLPTDEGEPRVKALMAAFATERQSLSDSLKK---LASQLQISETKNADLRDDAER 1515 Query: 1543 L-QNMVRASSSKIQKHVSFASDTKQGRDEQ 1571 L +++++A + + T+ R+ Q Sbjct: 1516 LKRDLLKAERVEEDLRRNLVEQTEIMRENQ 1545 Score = 86.2 bits (204), Expect = 7e-15 Identities = 199/987 (20%), Positives = 403/987 (40%), Gaps = 106/987 (10%) Query: 633 LQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIE-NLKLDKEQ 691 LQ+K +E ++ D + S Q ++ S ++E D K A E +LD+E+ Sbjct: 102 LQRKIEEYRRRIVDAEKQVSIQKANDDVSFSIKETADTWLPDMKSDAADYEWASRLDEER 161 Query: 692 LYGTIKDLENDKEDI-MNKLQNYIQENMDLTDKLEKMSAEKISELLAKINH------EEQ 744 ++ ++ + + +LQ Y + NM +K+ + + ++ L EE Sbjct: 162 RRNDELHMQITQQQVDLQRLQKYFEANMQEKEKIYQTREKNLAYYLNAEQRKMLDLWEEL 221 Query: 745 SKIQTQFGIDAKIQERDLYIENIESELSKYKSRI--------------CRLEESIAVMED 790 +++ QF + ERDL EN ++E++K + L + + ++E Sbjct: 222 QRVRRQFADYKEQTERDL--ENQKNEVAKVTQSVGGMAGRLNTSSHGDSGLVQDVVLLEA 279 Query: 791 RRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKE 850 R E +A +G+ + +Y +E V R+ L H ++L +E E Sbjct: 280 MRRFRELQAVPVGASADDYNALMKKY----EETVERVIELESHGDGSTAKMLSLE---AE 332 Query: 851 LQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRI 910 L++ +E ++ L+ L D+ E+ ++ +++ N+ R Sbjct: 333 LRRTKDKFIECSEFLR-KLGDLAAGSYRGDERTSKIVSLSPGGMSLPSEIYRSVRNILR- 390 Query: 911 THEHQTLIVQKKKEIEDLEI-EFNTQIESAIR-----DKKVLNEKYEKNIEY--VTQLEA 962 H+ + +Q+K + D ++ E T++E DK++++ K E NI+ V Sbjct: 391 NHDSEMQHIQRKLKNSDTQVCELTTRLEGTEEARRRSDKQLVDAKREINIQQRAVDDANR 450 Query: 963 QLQEYKNNIENLNMN--VEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQ 1020 +L+ ++ + + V E + LE + + Q QS E+ + E ++ + + Sbjct: 451 ELRRVEDRLHIMESEKIVAENARQQLEEEVRRLTLQVDQSKADGERRVVEEGEIQKRIVE 510 Query: 1021 KDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSK---QH 1077 +E ++ ++ ++ ++ L +L+N+E E ++L D +H Sbjct: 511 --DEYRSMISELTRRMNAFQDENKRLKNDLGCTKERLKNVEFEYNSTVRKLEDKDIALKH 568 Query: 1078 NEELQI-LVREQDDQ-------IKELKETKLTFEM---NIPKTEGMIISSTIEPMSDD-A 1125 E+ ++ L+++ ++Q EL + TFE NI + E I I M D+ + Sbjct: 569 LEDTKLDLLKDLENQRTRYDAVTNELDTLQTTFETSTKNIAQLEANI--KEINLMRDEIS 626 Query: 1126 NNVDXXXXXXXXXXXXLKVQE-EEEFIQERSV-LQEQSAKLNTELQECYTKIIQLETLNT 1183 D L+++ E IQ V E K ++ E +++ L LN Sbjct: 627 KEKDSLAQKLADVTHKLEIETVRREDIQRSCVGHSEDVEKQRLQIIEYEREVMALRRLND 686 Query: 1184 ELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVD--QRGFEIAELWKQ 1241 EL + Q ++ L++ + + TE L + +L+ S + Q+ +L K+ Sbjct: 687 ELDTNVKTGQAKVTSLENSIISVQTEVTKLTTLNDKLQKEKQSIMSSKQKADTDVDLLKE 746 Query: 1242 HLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQD 1301 L + E + K + E + + EQ+ + +EE ++I +E+ L++ + + Sbjct: 747 KLRKLEQECDKLKEENKAL-----HEDEQI---ARQMCKEEASRIHLLER--DLKDAMTE 796 Query: 1302 KEEHLRNLQEKYADVINQIE-ILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYK 1360 EE + LQ+ + ++E +LR++I + V +LR + YK Sbjct: 797 VEELKKQLQKMDEENSERLESVLRTKISSDTV----DTSEIAEYTEVKVKELR---EKYK 849 Query: 1361 QMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKT 1420 E+ L N+++ + + E L+L +QLE T Sbjct: 850 ADLER--LQSNKDDLERRVQILEDELAERQRIVERQRTEMNDLKLEYQLESDRLRAEMAT 907 Query: 1421 HEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKES 1480 E + E E+ R Q + + E S+++ + KM E A H ET+ +E Sbjct: 908 VEL-----KYQSEVEDERDQRSRDADSWKVTSEELRSKISFME-KMLEEAKHRETVLRE- 960 Query: 1481 EIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNE----MQTALENQEIEIVTL 1536 E + E+ ++ ES+ L ++ + EE++ K + Q L+N E TL Sbjct: 961 --EATEWEEKHDIISNESLKLRNEIERIRSDAEEDIQKWKKDVHMAQNELKNLERVCETL 1018 Query: 1537 -------NDEITNLQNMVRASSSKIQK 1556 ND + +L + +SKI++ Sbjct: 1019 RSQLTAANDRVASLNTTINEQTSKIRE 1045 Score = 72.1 bits (169), Expect = 1e-10 Identities = 160/879 (18%), Positives = 353/879 (40%), Gaps = 80/879 (9%) Query: 695 TIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKI-NHEEQSKIQ-TQFG 752 ++ L+ D ++ +E + D + + KI E +I + E+Q IQ Sbjct: 70 SVSGLDRDLNSFKKRIDANTEEQREHADMMVGLQ-RKIEEYRRRIVDAEKQVSIQKANDD 128 Query: 753 IDAKIQER-DLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQK 811 + I+E D ++ +++S+ + Y+ RL+E R L + Q LQ QK Sbjct: 129 VSFSIKETADTWLPDMKSDAADYEWA-SRLDEE----RRRNDELHMQITQQQVDLQRLQK 183 Query: 812 AYSEYTIQEDELV--NRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQ-NLQIS 868 Y E +QE E + R L + ++++L++ E + ++++ E+ + +L+ Sbjct: 184 -YFEANMQEKEKIYQTREKNLAYYLNAEQRKMLDLWEELQRVRRQFADYKEQTERDLENQ 242 Query: 869 LSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDL 928 +++ + ++ A R + + + + LE+ ++R + + L Sbjct: 243 KNEVAKVTQSVGGMAGRLNTSSHGDSGLVQDVVLLEA-MRRFRELQAVPVGASADDYNAL 301 Query: 929 EIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLEL 988 ++ +E I L + + + LEA+L+ K+ + + +L + Sbjct: 302 MKKYEETVERVIE----LESHGDGSTAKMLSLEAELRRTKDKFIECSEFLRKLGDLAAGS 357 Query: 989 I--DKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDY 1046 D+ K + SP + +L+ D E+ + +K+ N+ Sbjct: 358 YRGDERTSKIVSLSPGGMSLPSEIYRSVRNILRNHDSEMQHIQRKLKNS----------- 406 Query: 1047 ESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNI 1106 ++++ + TT+LE EE +R KQL+D+K+ E+ I R DD +EL+ ++ ++I Sbjct: 407 DTQVCELTTRLEGTEEARRRSDKQLVDAKR---EINIQQRAVDDANRELR--RVEDRLHI 461 Query: 1107 PKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNT 1166 ++E ++ + + + ++ + V+E E IQ+R V E Sbjct: 462 MESEKIVAENARQQLEEEVRRLTLQVDQSKADGERRVVEEGE--IQKRIVEDE------- 512 Query: 1167 ELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISS 1226 Y +I +ELT Q++ +LK+ L + L + E S++ Sbjct: 513 -----YRSMI------SELTRRMNAFQDENKRLKN---DLGCTKERLKNVEFEYNSTV-- 556 Query: 1227 AVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKI 1286 R E ++ +HL + D K R + A ++ + L + ++ST+ Sbjct: 557 ----RKLEDKDIALKHLEDTKLDLLKDLENQRTRYDAVTNELDTLQTTFETSTKNIAQLE 612 Query: 1287 VTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXX 1346 ++++ +++++ +++ +L +K ADV +++EI ED + + Sbjct: 613 ANIKEINLMRDEISKEKD---SLAQKLADVTHKLEIETVRREDIQRS-CVGHSEDVEKQR 668 Query: 1347 XXXXDLRTENQSYKQMQEQSILNINEENAQLK--KSSXXXXXXXXXXXXRVNDAEAKVLE 1404 + E + +++ ++ N+ A++ ++S +ND K + Sbjct: 669 LQIIEYEREVMALRRLNDELDTNVKTGQAKVTSLENSIISVQTEVTKLTTLNDKLQKEKQ 728 Query: 1405 LTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRL 1464 + K E L Q D+ + + L E E+ + E+ S + +L Sbjct: 729 SIMSSKQKADTDVDLLKEKLRKLEQECDKLKEENKALHEDEQIARQMCKEEASRIHLLER 788 Query: 1465 KMHENANHYE----TMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEV---- 1516 + + E +QK E +L L KI+ ++AE + +E+ Sbjct: 789 DLKDAMTEVEELKKQLQKMDEENSERLESVLRTKISSDTVDTSEIAEYTEVKVKELREKY 848 Query: 1517 -AKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKI 1554 A +Q+ ++ E + L DE+ Q +V +++ Sbjct: 849 KADLERLQSNKDDLERRVQILEDELAERQRIVERQRTEM 887 >UniRef50_Q8IWJ2 Cluster: GRIP and coiled-coil domain-containing protein 2; n=25; Euteleostomi|Rep: GRIP and coiled-coil domain-containing protein 2 - Homo sapiens (Human) Length = 1583 Score = 126 bits (304), Expect = 5e-27 Identities = 243/1171 (20%), Positives = 499/1171 (42%), Gaps = 127/1171 (10%) Query: 473 EDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSA-EEQITQLNDEIDAAN-------- 523 E +N ++ EQLK + N E +++ IEK++ EEQI L ++DA Sbjct: 57 EAMNTQLELSEQLKFQNNSEDNVKKLQEEIEKIRPGFEEQILYLQKQLDATTDEKKETVT 116 Query: 524 --KNMIKVKSNHKLK-LKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGN 580 +N+I+ S H K + +Q+ + + +E+ L ++ S K E E K N Sbjct: 117 QLQNIIEANSQHYQKNINSLQEELLQLKAIHQ--EEVKELMCQIE-ASAKEHEAEINKLN 173 Query: 581 -LQLHLVDYDSGRMIESDVYKKM-IEMENLAETRLKA-----ISLLESQKFDLVQELHIL 633 L+ +LV E ++ KK E+ENL + A I + Q+ V++ ++ Sbjct: 174 ELKENLVKQCEAS--EKNIQKKYECELENLRKATSNANQDNQICSILLQENTFVEQ--VV 229 Query: 634 QQKYDEVEDKLADISQLQS---DQVCSEIKSVHLEEQIDALSAS------KKELALVIEN 684 +K +ED L ++ S D+V + + ++ L+ ++DA +++L I Sbjct: 230 NEKVKHLEDTLKELESQHSILKDEV-TYMNNLKLKLEMDAQHIKDEFFHEREDLEFKINE 288 Query: 685 LKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAK-INHEE 743 L L KE+ I+ L+++ + + ++++ L++ ++ISEL ++ E Sbjct: 289 LLLAKEEQGCVIEKLKSELAGLNKQFCYTVEQHNREVQSLKEQHQKEISELNETFLSDSE 348 Query: 744 QSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLG 803 + K+ F I ++E+ EN++ E + I E +ME + L A G Sbjct: 349 KEKLTLMFEIQG-LKEQ---CENLQQEKQE---AILNYESLREIMEILQTELGESA---G 398 Query: 804 SYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQ 863 QE + + EL +L + + + ++ EN++L + +++ E Sbjct: 399 KISQEFESMKQQQASDVHELQQKLRTAFTEKDALLETVNRLQGENEKLLSQQELVPE--- 455 Query: 864 NLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKK 923 L+ ++ ++Q+ + ++ D T L++LE + +T E I + K Sbjct: 456 -LENTIKNLQEKNGVYLLSLSQRD----------TMLKELEGKINSLTEEKDDFINKLKN 504 Query: 924 EIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENL----NMNVE 979 E+++ F+ + E R L +K E+ I+Y ++LE ++ E +E + N + Sbjct: 505 SHEEMD-NFHKKCEREERLILELGKKVEQTIQYNSELEQKVNELTGGLEETLKEKDQNDQ 563 Query: 980 ELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEI-IALNQKINNAQVS 1038 +L K+ +++ K + + + + E NKL++ KQ ++ + L+QK V Sbjct: 564 KLEKLMVQM--KVLSEDKEVLSAEVKSLYEENNKLSSEKKQLSRDLEVFLSQK---EDVI 618 Query: 1039 YMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKET 1098 ++ E KL + +N+ + ++ Q L K +L ++E ++ E E Sbjct: 619 LKEHITQLEKKLQLMVEEQDNLNKLLENEQVQKLFVKT---QLYGFLKEMGSEVSEDSEE 675 Query: 1099 KLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQ 1158 K +N+ + G ++ E + A D L++++E + +QE SV+Q Sbjct: 676 KDV--VNVLQAVGESLAKINEEKCNLAFQRDEKV---------LELEKEIKCLQEESVVQ 724 Query: 1159 EQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVA 1218 + +L + L++ + + L E+ Q + ++K+ E+ EN NLL V Sbjct: 725 CE--ELKSLLRDYEQEKVLLRKELEEIQSEKEALQSDLLEMKNANEKTRLENQNLLIQVE 782 Query: 1219 ELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSS 1278 E+ + S + E + K+H + QK + R +L + + SV++ Sbjct: 783 EVSQTCSKSEIHNEKEKCFI-KEHENLKPLLEQKELRDRRAELILLKDSLAKS-PSVKND 840 Query: 1279 TQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXX 1338 ++ E++ +L+ + ++KEE + ++ +++ R E + K Sbjct: 841 PLSSVKELE--EKIENLEKECKEKEEKINKIKLVAVKAKKELDSSRKETQTVKEELESLR 898 Query: 1339 XXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDA 1398 DL +SYK + +L +++ QL R N+ Sbjct: 899 SEKDQLSASMR-DLIQGAESYKNL----LLEYEKQSEQLDVEKE-----------RANNF 942 Query: 1399 EAKVLELTHQLE---LKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEK 1455 E ++ +LT QL L+ I + + + + Q++E ++ + E Sbjct: 943 EHRIEDLTRQLRNSTLQCETINSDNEDLLARIETLQSNAKLLEVQILEVQRAKAMVDKEL 1002 Query: 1456 ESELAILRLKMHENA---NHYETMQKESEIERVKL---IEELNV---KITESVSLNKQVA 1506 E+E K+ E+A N E +Q + + ++ +L ++EL + ++ +N ++A Sbjct: 1003 EAEKLQKEQKIKEHATTVNELEELQVQLQKQKKQLQKTMQELELVKKDAQQTTLMNMEIA 1062 Query: 1507 ELNKALEEEVAKTNEMQTALEN--QEIEIV-----TLNDEITNLQNMVRASSSKIQKHVS 1559 + + ++E K +E+ QEI+I TL +EIT+LQ+ V+ K K Sbjct: 1063 DYERLMKELNQKLTNKNNKIEDLEQEIKIQKQKQETLQEEITSLQSSVQQYEEKNTKIKQ 1122 Query: 1560 FASDTKQGRDEQLDNTMNKELLDAVPRAELD 1590 TK+ + + +L A + EL+ Sbjct: 1123 LLVKTKKELADSKQAETDHLILQASLKGELE 1153 Score = 98.3 bits (234), Expect = 2e-18 Identities = 191/963 (19%), Positives = 380/963 (39%), Gaps = 81/963 (8%) Query: 144 VTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKIN----EKDQII-EAKNKATTXXXX 198 V L NTIK V + + +T + +L+ KIN EKD I + KN Sbjct: 453 VPELENTIKNLQEKNGVYLLSLSQRDTMLKELEGKINSLTEEKDDFINKLKNSHEEMDNF 512 Query: 199 XXXXXXXXXXXXXEDTKQQMTKMQENFIAMEA-EWKDEKQRLLKDIESKDVRISSLEEAN 257 K + T + + + E + LK+ + D ++ L Sbjct: 513 HKKCEREERLILELGKKVEQTIQYNSELEQKVNELTGGLEETLKEKDQNDQKLEKLMVQM 572 Query: 258 KLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEK-TEIEEKGSL 316 K+L + +S E L +E + Q + +E T++E+K L Sbjct: 573 KVLSEDKEVLSAEVKSLYEENNKLSSEKKQLSRDLEVFLSQKEDVILKEHITQLEKKLQL 632 Query: 317 EIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPL-ISRKSG 375 + L K LLE+ Q +L L MG+E VS S++ + + + G Sbjct: 633 MVEEQDNLNK---LLENEQVQKLFVKTQLYGFLKEMGSE---VSEDSEEKDVVNVLQAVG 686 Query: 376 RNTASKMKSPWS---QLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKD 432 + A + + Q + L + + K + E ++SL +D ++E V+ K+ Sbjct: 687 ESLAKINEEKCNLAFQRDEKVLELEKEIKCLQEESVVQCEELKSLLRD-YEQEKVLLRKE 745 Query: 433 TXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDE 492 D L+ + +E +L+ E+V++ E ++ Sbjct: 746 LEEIQSEKEALQSD-LLEMKNANEKTRLENQNLL---IQVEEVSQTCSKSEIHNEKEKCF 801 Query: 493 IKD-VNVKDLIE--KLKSAEEQITQLNDEI----DAANKNMIKVK------SNHKLKLKQ 539 IK+ N+K L+E +L+ ++ L D + N + VK N + + K+ Sbjct: 802 IKEHENLKPLLEQKELRDRRAELILLKDSLAKSPSVKNDPLSSVKELEEKIENLEKECKE 861 Query: 540 MQKTIDNFSKVS-DSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDV 598 ++ I+ V+ + KE+ +E + +++ L EK L + D G ++ Sbjct: 862 KEEKINKIKLVAVKAKKELDSSRKETQTVKEELESLRSEKDQLSASMRDLIQGAESYKNL 921 Query: 599 YKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEV----EDKLADISQLQSDQ 654 + + + + + E + DL ++L + + + ED LA I LQS+ Sbjct: 922 LLEYEKQSEQLDVEKERANNFEHRIEDLTRQLRNSTLQCETINSDNEDLLARIETLQSNA 981 Query: 655 VCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYI 714 E++ + ++ A + KEL E KL KEQ N+ E++ +LQ Sbjct: 982 KLLEVQILEVQR---AKAMVDKEL----EAEKLQKEQKIKEHATTVNELEELQVQLQKQK 1034 Query: 715 QENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKY 774 ++ +LE + + L + + ++ + ++ K+ ++ IE++E E+ Sbjct: 1035 KQLQKTMQELELVKKDAQQTTLMNMEIADYERLMKE--LNQKLTNKNNKIEDLEQEIKIQ 1092 Query: 775 KSR-------ICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRL 827 K + I L+ S+ E++ +++ + L + ++A +++ I + L L Sbjct: 1093 KQKQETLQEEITSLQSSVQQYEEKNTKIKQLLVKTKKELADSKQAETDHLILQASLKGEL 1152 Query: 828 AVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTD 887 V + QL EI E ++ + + E++Q +LS QQ AL E+ Sbjct: 1153 EASQQQVEVYKIQLAEITSEKHKIHEHLKTSAEQHQR---TLSAYQQRVTALQEECR--- 1206 Query: 888 LAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQ----IESAIRDK 943 A++E T + ES R+ H L QK K + E E Q +E I Sbjct: 1207 AAKAEQA---TVTSEFESYKVRV---HNVLKQQKNKSMSQAETEGAKQEREHLEMLIDQL 1260 Query: 944 KVLNEKYEKNIEY-VTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDK--HVQKQQTQS 1000 K+ + + N++ V++L+ E+ +E N ++E EL +K +Q + Sbjct: 1261 KIKLQDSQNNLQINVSELQTLQSEHDTLLERHNKMLQETVSKEAELREKLCSIQSENMMM 1320 Query: 1001 PDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENM 1060 Q ++++ N +L+ + ++ + Q + V + +L++ +L + Sbjct: 1321 KSEHTQTVSQLTSQNEVLRN------SFRDQVRHLQEEHRKTVETLQQQLSKMEAQLFQL 1374 Query: 1061 EEE 1063 + E Sbjct: 1375 KNE 1377 Score = 80.2 bits (189), Expect = 4e-13 Identities = 141/689 (20%), Positives = 293/689 (42%), Gaps = 85/689 (12%) Query: 907 LKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQE 966 +K+ + T + KE+E I + +IE+ + + KY E L+ QL+E Sbjct: 1 MKQEVEDSVTKMGDAHKELEQSHINYVKEIENLKNELMAVRSKYS---EDKANLQKQLEE 57 Query: 967 YKNNIENLNMNVEELNKM--NLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEE 1024 N L+ ++ N N++ + + ++K + P + EQ + +L+A +K E Sbjct: 58 AMNTQLELSEQLKFQNNSEDNVKKLQEEIEKIR---PGFEEQILYLQKQLDATTDEKKET 114 Query: 1025 IIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQIL 1084 + L I Y ++ + +L Q K + EE + + + +K+H E+ L Sbjct: 115 VTQLQNIIEANSQHYQKNINSLQEELLQL--KAIHQEEVKELMCQIEASAKEHEAEINKL 172 Query: 1085 VREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKV 1144 +++ +K+ + + E NI K + + + + +AN + + Sbjct: 173 NELKENLVKQCEAS----EKNIQKKYECELEN-LRKATSNANQDNQICSI---------L 218 Query: 1145 QEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLE 1204 +E F+++ V+ E+ L L+E + Q L E+T +N LK KLE Sbjct: 219 LQENTFVEQ--VVNEKVKHLEDTLKELES---QHSILKDEVT--------YMNNLKLKLE 265 Query: 1205 -QLNTENDNLLSTVAELRSSISS---AVDQRGFEIAELWKQHLAQREADFQKTEHELRVQ 1260 D +L I+ A +++G I +L K LA F T + + Sbjct: 266 MDAQHIKDEFFHEREDLEFKINELLLAKEEQGCVIEKL-KSELAGLNKQFCYTVEQHNRE 324 Query: 1261 LSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQI 1320 + + + ++++ + + + ++ K E++T L ++Q +E NLQ++ + I Sbjct: 325 VQSLKEQHQKEISELNETFLSDSEK----EKLT-LMFEIQGLKEQCENLQQEKQEAILNY 379 Query: 1321 EILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKS 1380 E LR +E + +Q ++ M++Q +++E +L ++ Sbjct: 380 ESLREIMEILQTELGESAGKI--------------SQEFESMKQQQASDVHELQQKL-RT 424 Query: 1381 SXXXXXXXXXXXXRVNDAEAKVL---ELTHQLELKDSEIYQKTHEYTITLTQRNDEFENV 1437 + R+ K+L EL +LE + +K Y ++L+QR+ Sbjct: 425 AFTEKDALLETVNRLQGENEKLLSQQELVPELENTIKNLQEKNGVYLLSLSQRD------ 478 Query: 1438 RQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITE 1497 L E E +I LT EK+ + L+ E N ++ ++E +LI EL K+ + Sbjct: 479 -TMLKELEGKINSLTEEKDDFINKLKNSHEEMDNFHKKCEREE-----RLILELGKKVEQ 532 Query: 1498 SVSLN----KQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSK 1553 ++ N ++V EL LEE + + ++ LE +++ L+++ L V+ S Sbjct: 533 TIQYNSELEQKVNELTGGLEETLKEKDQNDQKLEKLMVQMKVLSEDKEVLSAEVK---SL 589 Query: 1554 IQKHVSFASDTKQ-GRDEQLDNTMNKELL 1581 +++ +S+ KQ RD ++ + ++++ Sbjct: 590 YEENNKLSSEKKQLSRDLEVFLSQKEDVI 618 Score = 76.6 bits (180), Expect = 5e-12 Identities = 152/707 (21%), Positives = 290/707 (41%), Gaps = 72/707 (10%) Query: 837 VEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKY 896 VE + ++ +KEL++ + ++E +NL+ L ++ Y+ +KAN L + Sbjct: 5 VEDSVTKMGDAHKELEQSHINYVKEIENLKNELMAVRSKYSE--DKAN---LQKQLEEAM 59 Query: 897 QTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEY 956 TQL +L LK + + + + ++EIE + F QI + +K L+ ++ E Sbjct: 60 NTQL-ELSEQLK-FQNNSEDNVKKLQEEIEKIRPGFEEQI---LYLQKQLDATTDEKKET 114 Query: 957 VTQL----EAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEIN 1012 VTQL EA Q Y+ NI +L + +L ++ E V++ Q +++ EIN Sbjct: 115 VTQLQNIIEANSQHYQKNINSLQEELLQLKAIHQE----EVKELMCQIEASAKEHEAEIN 170 Query: 1013 KLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLL 1072 KLN L + + + S ++ YE +L N ++ Q S L Sbjct: 171 KLNELKE----------NLVKQCEASEKNIQKKYECELENLRKATSNANQDNQICSILLQ 220 Query: 1073 DSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXX 1132 ++ + + V+ +D +KEL+ + + + + ++ Sbjct: 221 ENTFVEQVVNEKVKHLEDTLKELESQHSILKDEVTYMNNLKLKLEMDAQHIKDEFFHERE 280 Query: 1133 XXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVN 1192 L +EE+ + E+ L+ + A LN Q CYT +E N E+ + Sbjct: 281 DLEFKINELLLAKEEQGCVIEK--LKSELAGLNK--QFCYT----VEQHNREVQSLKEQH 332 Query: 1193 QEQINQL-KSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQ 1251 Q++I++L ++ L E L+ + L+ + ++ + A L + L + Q Sbjct: 333 QKEISELNETFLSDSEKEKLTLMFEIQGLKEQCENLQQEK--QEAILNYESLREIMEILQ 390 Query: 1252 KTEHELRVQLS-AFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQ 1310 E ++S FES +Q V Q+ + + N+LQ + E L + Q Sbjct: 391 TELGESAGKISQEFESMKQQQASDVHELQQKLRTAFTEKDALLETVNRLQGENEKLLSQQ 450 Query: 1311 EKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNI 1370 E ++ N I+ L+ + L + K++ E I ++ Sbjct: 451 ELVPELENTIKNLQEK------------------NGVYLLSLSQRDTMLKEL-EGKINSL 491 Query: 1371 NEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELK---DSEIYQKTHEYTITL 1427 EE + E +LEL ++E +SE+ QK +E T L Sbjct: 492 TEEKDDFINKLKNSHEEMDNFHKKCEREERLILELGKKVEQTIQYNSELEQKVNELTGGL 551 Query: 1428 TQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKL 1487 + E + Q+L + +++ L+ +KE A E + YE K S E+ +L Sbjct: 552 EETLKEKDQNDQKLEKLMVQMKVLSEDKEVLSA-------EVKSLYEENNKLSS-EKKQL 603 Query: 1488 IEELNVKIT--ESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIE 1532 +L V ++ E V L + + +L K L+ V + + + LEN++++ Sbjct: 604 SRDLEVFLSQKEDVILKEHITQLEKKLQLMVEEQDNLNKLLENEQVQ 650 >UniRef50_Q245H6 Cluster: Putative uncharacterized protein; n=1; Tetrahymena thermophila SB210|Rep: Putative uncharacterized protein - Tetrahymena thermophila SB210 Length = 1610 Score = 126 bits (303), Expect = 7e-27 Identities = 188/911 (20%), Positives = 378/911 (41%), Gaps = 83/911 (9%) Query: 449 IAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSA 508 IA LQ E +Q +E + T++V + K+Q++ L ++I + N K L + L+ + Sbjct: 324 IADLQAEMKQILEKLQM-----QTDEVERLKKLQQETIDTLQNKI-EFNEKSLRDNLEES 377 Query: 509 EEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVR--LTEELHH 566 + I +I N+ + ++ + K + +K +D+ ++ ++ L + Sbjct: 378 QRIIANQQVDIQYKNRQIAELSQKLTQSITDHAKQLQLLAKEADAQRDDIQQELIANSNA 437 Query: 567 LSQKVAELEEEKGNLQL-HLVDYDSGRMIESDVYKK---MIEMENLAETRLKAISLLESQ 622 L + +L+ + +Q + V +D + + D + K + E+E + I+ L+ + Sbjct: 438 LENDIQDLKSQLTRIQNENTVLHDENKKLFYDSHSKENRIKELEGQIKQNQSKINDLQQK 497 Query: 623 KFDLVQELHILQQKYDEVE--------DKLADISQLQSD----QVCSEIKSVH--LEEQI 668 DL + + L ++ ++ D A I+Q + Q +++++H L+E++ Sbjct: 498 LEDLNKLSNHLDEQNRSLDAQNQQFFNDNKALIAQTEEQEKAIQNLKDLETLHIQLQEKL 557 Query: 669 DALSASKKELALV----IENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKL 724 + + K LA IE + K QL+ + E +K ++ + + L ++ Sbjct: 558 KLIESEKASLAQTAQQHIEESEKYKNQLFELQQGQEKEKRYALDGQMRLKENEVSLKIEV 617 Query: 725 EKMSAE-KISELL--AKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRL 781 E+ +E K ++LL K++ +++ Q +++ E+ +E + KY+ + Sbjct: 618 ERQQSEIKHNQLLFEEKLSTKQKEIEFIQIQLNSTTSEKVKCLETLSELTKKYEQQ---- 673 Query: 782 EESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQL 841 +E + +++++ LE K + L + LQEK A+ + +IQ D L + + +Q+ Sbjct: 674 KEKLKDLQEQKIQLEAKINNLEALLQEKNNAFEKTSIQIDLLTQESQTIKEQYNQKVRQI 733 Query: 842 LEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAE--SESTKYQTQ 899 ++ EN K +NQ L L D+ Q N VEK DL + SE + Q Q Sbjct: 734 -SLQEENISQYAK------DNQKLNNELKDLLQEKNN-VEKKLLLDLQQKTSEVAQLQQQ 785 Query: 900 LRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQ 959 ++ + L+ +H + ++K +E F + + ++ E+ E+ IE +T+ Sbjct: 786 IKATQKQLQFEAQQHNLQVEREKLYMEQQLKTFEQKCQELQQNLIQKEEEQEEFIEQLTE 845 Query: 960 LEAQLQEYKNNIENLNMNVEE----LNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLN 1015 E L E +N IE L + ++ LN L+L D QK++ +Q +KL Sbjct: 846 KETMLNEQRNQIEELKLQFQKEEDSLNSEILQLQDSLKQKEKQYHIYQKQQKEYTQDKLK 905 Query: 1016 ALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSK 1075 +L E Q + Q S ++D S+ Q+ + E + K D++ Sbjct: 906 GVLSSLAEA----RQDLTIFQSKCNSEINDTHSRTLQYFQDIMQFSREQKSKLKVQYDNE 961 Query: 1076 QHNEELQILVREQDDQIKE---LKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXX 1132 + I + + KE ++E + F I E ++ ++ Sbjct: 962 MEKYQENISTKFETQLDKERLIMRERESHFNKQISLLEQKVLEQNTR-FQEEKQKYQQEI 1020 Query: 1133 XXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVN 1192 K+Q E IQ ++ L + ++ +++ QLE +N V+ Sbjct: 1021 NSLEERNITEKIQLNNEIIQLKNQLLKVESRSARSVEKNQK---QLEMVNQNAQKSQVMY 1077 Query: 1193 QEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQK 1252 I+ +K+KLE+ + L + E RS I + K HL Q E + Sbjct: 1078 ANMISDIKNKLEESEKKE---LQVLNETRSKIHN------------MKAHLQQIELEDSN 1122 Query: 1253 TEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNK--LQDKEEHLRNLQ 1310 + ++ +K D S+ TN I + SLQN LQ + LQ Sbjct: 1123 EQLAHSTSSTSSMNKQNSNNDGRSSNNLNNTNNI----NIDSLQNNTLLQTQRTARLALQ 1178 Query: 1311 EKYADVINQIE 1321 ++Y + + Sbjct: 1179 KEYEKTMKNFQ 1189 Score = 123 bits (297), Expect = 4e-26 Identities = 213/1074 (19%), Positives = 475/1074 (44%), Gaps = 101/1074 (9%) Query: 509 EEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLS 568 +E IT L++ ++ ++K + +L Q ++ + SK++ N+ E+L + Sbjct: 60 DELITTLSESQTSSEFIEERIKEIIENQLFQEKEQV--ISKLASDNQAFQLKIEQLEIDN 117 Query: 569 QKVAELEEEKGNLQLHLVDYDSGRMIES--DVYKKMIEMENLAETRLKAISLLESQKFDL 626 Q +A + N Q++ ++Y+ ++ ++ ++ +K +E L + + L+ +K +L Sbjct: 118 QTLASSIQSVHN-QVNNLNYEGDKLKKNTLELNEKDARIEQLLDKITRQEGQLQ-EKENL 175 Query: 627 VQELHILQQKYD---EVE-DKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVI 682 +Q+ I +Q+ + + E +KL + QLQ + E++ +L+++ D L + +L Sbjct: 176 IQQKDIDKQRVELQLQTERNKLTHVDQLQGVE---EVEKKNLQQKYDELLSKYDKLNEEF 232 Query: 683 ENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHE 742 ++L EQ+ G + N++E + + D T L K+ ++ ++ E Sbjct: 233 NGIRLRYEQI-GV--ERINEQEQYKLLIDQIKVKCKDKTHNL-KIKYKQYKDMSRNFQ-E 287 Query: 743 EQSKIQTQFGI-DAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQ 801 + + +T+F + ++ E + ++ + +Y+ +I L+ A M+ L+ + D+ Sbjct: 288 KLIQNETEFSNKNLQVNEMKIKVQESSRAIIEYQRQIADLQ---AEMKQILEKLQMQTDE 344 Query: 802 LGSYLQEKQKAYSEYTIQEDELVNRLAVLMD--HDRVVEKQLLEIEHENKELQKKNQILL 859 + E+ K + TI D L N++ D + E Q + I ++ ++Q KN+ + Sbjct: 345 V-----ERLKKLQQETI--DTLQNKIEFNEKSLRDNLEESQRI-IANQQVDIQYKNRQIA 396 Query: 860 EENQNLQISLSDMQQHYNALVEKAN--RTDLAE---SESTKYQTQLRDLESNLKRITHEH 914 E +Q L S++D + L ++A+ R D+ + + S + ++DL+S L RI +E+ Sbjct: 397 ELSQKLTQSITDHAKQLQLLAKEADAQRDDIQQELIANSNALENDIQDLKSQLTRIQNEN 456 Query: 915 QTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENL 974 L + KK D + N + +LE Q+++ ++ I +L Sbjct: 457 TVLHDENKKLFYDSHSKENR----------------------IKELEGQIKQNQSKINDL 494 Query: 975 NMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINN 1034 +E+LNK++ H+ +Q +Q+ N+ L A +++++ I L + Sbjct: 495 QQKLEDLNKLS-----NHLDEQNRSLDAQNQQFFNDNKALIAQTEEQEKAIQNLKD-LET 548 Query: 1035 AQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKE 1094 + + ES+ A + EE ++ QL + +Q E+ + D Q++ Sbjct: 549 LHIQLQEKLKLIESEKASLAQTAQQHIEESEKYKNQLFELQQGQEKEKRYAL--DGQMR- 605 Query: 1095 LKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQ-E 1153 LKE +++ ++ + + + I + + + ++ + Q+E EFIQ + Sbjct: 606 LKENEVSLKIEVERQQSEIKHNQL--LFEEKLSTK---------------QKEIEFIQIQ 648 Query: 1154 RSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNT--END 1211 + + K L E K Q + +L + + +IN L++ L++ N E Sbjct: 649 LNSTTSEKVKCLETLSELTKKYEQQKEKLKDLQEQKIQLEAKINNLEALLQEKNNAFEKT 708 Query: 1212 NL-LSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQ 1270 ++ + + + +I +Q+ +I+ L +++++Q D QK +EL+ L + ++ Sbjct: 709 SIQIDLLTQESQTIKEQYNQKVRQIS-LQEENISQYAKDNQKLNNELKDLLQEKNNVEKK 767 Query: 1271 LLDSVQSSTQEETNKIVTMEQVTSLQNKLQ-DKEEHLRNLQEKYADVINQIEILRSEIED 1329 LL +Q T E +Q+ + Q +LQ + ++H ++ + + Q++ + ++ Sbjct: 768 LLLDLQQKTSEVAQ---LQQQIKATQKQLQFEAQQHNLQVEREKLYMEQQLKTFEQKCQE 824 Query: 1330 EKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXX 1389 + N+ Q++E L +E L Sbjct: 825 LQQNLIQKEEEQEEFIEQLTEKETMLNEQRNQIEELK-LQFQKEEDSLNSEILQLQDSLK 883 Query: 1390 XXXXRVNDAEAKVLELTHQLELKD--SEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKR 1447 + + + + E T Q +LK S + + + TI ++ N E + + ++Y + Sbjct: 884 QKEKQYHIYQKQQKEYT-QDKLKGVLSSLAEARQDLTIFQSKCNSEINDTHSRTLQYFQD 942 Query: 1448 IEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLI-EELNVKITESVSLNKQ-V 1505 I + E++S+L + E + + E+++++ +LI E + +SL +Q V Sbjct: 943 IMQFSREQKSKLKVQYDNEMEKYQENISTKFETQLDKERLIMRERESHFNKQISLLEQKV 1002 Query: 1506 AELNKALEEEVAKTNEMQTALENQEI-EIVTLNDEITNLQNMVRASSSKIQKHV 1558 E N +EE K + +LE + I E + LN+EI L+N + S+ + V Sbjct: 1003 LEQNTRFQEEKQKYQQEINSLEERNITEKIQLNNEIIQLKNQLLKVESRSARSV 1056 Score = 105 bits (252), Expect = 1e-20 Identities = 174/912 (19%), Positives = 398/912 (43%), Gaps = 82/912 (8%) Query: 458 QHMEGPSLIHVGTNTEDVNEIAKVQ---EQLKQELNDEIKDVNVKDLIEKLKSAEEQITQ 514 + G L + E +NE + + +Q+K + D+ ++ +K K S Q Sbjct: 230 EEFNGIRLRYEQIGVERINEQEQYKLLIDQIKVKCKDKTHNLKIKYKQYKDMSRNFQEKL 289 Query: 515 LNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSK-VSDSNKEIVRLTEELHHLSQKVAE 573 + +E + +NKN+ + K+K+++ + I + + ++D E+ ++ E+L + +V Sbjct: 290 IQNETEFSNKNL--QVNEMKIKVQESSRAIIEYQRQIADLQAEMKQILEKLQMQTDEVER 347 Query: 574 LEEEKGNLQLHLVDYDSGRM--IESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELH 631 L++ LQ +D ++ E + + E + + + I Q +L Q+L Sbjct: 348 LKK----LQQETIDTLQNKIEFNEKSLRDNLEESQRIIANQQVDIQYKNRQIAELSQKLT 403 Query: 632 ILQQKYDEVEDKLADISQLQSDQVCSEI--KSVHLEEQIDALSASKKELALVIENLKLDK 689 + + LA + Q D + E+ S LE I L + + L + Sbjct: 404 QSITDHAKQLQLLAKEADAQRDDIQQELIANSNALENDIQDLKSQLTRIQNENTVLHDEN 463 Query: 690 EQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMS--AEKISELLAKINHEEQSKI 747 ++L+ EN +++ +++ + DL KLE ++ + + E ++ + Q Sbjct: 464 KKLFYDSHSKENRIKELEGQIKQNQSKINDLQQKLEDLNKLSNHLDEQNRSLDAQNQQFF 523 Query: 748 QTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQ 807 + A+ +E++ I+N L ++ +L+E + ++E + SL + A Q +++ Sbjct: 524 NDNKALIAQTEEQEKAIQN----LKDLETLHIQLQEKLKLIESEKASLAQTAQQ---HIE 576 Query: 808 EKQKAYSE-YTIQEDELVNRLAVLMDHDRVVEKQL---LEIEHENKELQKKNQILLEENQ 863 E +K ++ + +Q+ + + L R+ E ++ +E+E + E+ K NQ+L EE Sbjct: 577 ESEKYKNQLFELQQGQEKEKRYALDGQMRLKENEVSLKIEVERQQSEI-KHNQLLFEE-- 633 Query: 864 NLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKK 923 LS Q+ + + N T SE K LE+ L +T +++ Q+K+ Sbjct: 634 ----KLSTKQKEIEFIQIQLNST---TSEKVKC------LET-LSELTKKYE----QQKE 675 Query: 924 EIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVT-QLEAQLQEYKNNIENLNMNVEE-- 980 +++DL+ E Q+E+ I + + L ++ E + Q++ QE + E N V + Sbjct: 676 KLKDLQ-EQKIQLEAKINNLEALLQEKNNAFEKTSIQIDLLTQESQTIKEQYNQKVRQIS 734 Query: 981 LNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYM 1040 L + N+ K QK + D ++ N KL L+QK E+ L Q+I Q Sbjct: 735 LQEENISQYAKDNQKLNNELKDLLQEKNNVEKKLLLDLQQKTSEVAQLQQQIKATQKQLQ 794 Query: 1041 SMVSDY----ESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEEL-------QILVREQD 1089 + E + +L+ E++ Q + + L+ ++ EE + ++ EQ Sbjct: 795 FEAQQHNLQVEREKLYMEQQLKTFEQKCQELQQNLIQKEEEQEEFIEQLTEKETMLNEQR 854 Query: 1090 DQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEE 1149 +QI+ELK + E + +E + + +++ + + E Sbjct: 855 NQIEELK-LQFQKEEDSLNSEILQLQDSLKQKEKQYHIYQKQQKEYTQDKLKGVLSSLAE 913 Query: 1150 FIQERSVLQEQSAKLNTELQECYTKIIQL--ETLNTELTGHDVVNQEQINQLKSKLEQLN 1207 Q+ ++ Q +K N+E+ + +++ +Q + + + + N+++ E ++ Sbjct: 914 ARQDLTIFQ---SKCNSEINDTHSRTLQYFQDIMQFSREQKSKLKVQYDNEMEKYQENIS 970 Query: 1208 TENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESK 1267 T+ + L + S +++ L +Q + ++ FQ+ + + + ++++ E + Sbjct: 971 TKFETQLDKERLIMRERESHFNKQ----ISLLEQKVLEQNTRFQEEKQKYQQEINSLEER 1026 Query: 1268 YEQLLDSVQSSTQ--EETNKIVTME-----QVTSLQNKLQDKEEHLRNLQEKYADVINQI 1320 + + +Q + + + N+++ +E V Q +L+ ++ + Q YA++I+ I Sbjct: 1027 --NITEKIQLNNEIIQLKNQLLKVESRSARSVEKNQKQLEMVNQNAQKSQVMYANMISDI 1084 Query: 1321 EILRSEIEDEKV 1332 + E E +++ Sbjct: 1085 KNKLEESEKKEL 1096 Score = 103 bits (247), Expect = 4e-20 Identities = 185/911 (20%), Positives = 372/911 (40%), Gaps = 61/911 (6%) Query: 719 DLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSR- 777 DL E+ + ++S L KI ++E ++ ++ E + E IE++L + K + Sbjct: 37 DLYSFYEQRLSAQMSLLYQKIINDELITTLSESQTSSEFIEERIK-EIIENQLFQEKEQV 95 Query: 778 ICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVV 837 I +L + + LE L S +Q + + D+L L + D + Sbjct: 96 ISKLASDNQAFQLKIEQLEIDNQTLASSIQSVHNQVNNLNYEGDKLKKNTLELNEKDARI 155 Query: 838 EKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQ 897 E+ L +I + +LQ+K ++ +++ + Q +Q N L + E E Q Sbjct: 156 EQLLDKITRQEGQLQEKENLIQQKDIDKQRVELQLQTERNKLTHVDQLQGVEEVEKKNLQ 215 Query: 898 TQLRDLESNLKRITHE-------HQTLIVQKKKEIEDLEIEFNTQIESAIRDK-KVLNEK 949 + +L S ++ E ++ + V++ E E ++ + QI+ +DK L K Sbjct: 216 QKYDELLSKYDKLNEEFNGIRLRYEQIGVERINEQEQYKLLID-QIKVKCKDKTHNLKIK 274 Query: 950 YEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYIN 1009 Y++ + + +L + + N N+ V E+ K+ ++ + + + Q Q D + Sbjct: 275 YKQYKDMSRNFQEKLIQNETEFSNKNLQVNEM-KIKVQESSRAIIEYQRQIADLQAEMKQ 333 Query: 1010 EINKL-------NALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEE 1062 + KL L K + E I L KI + S + + + +A ++ Sbjct: 334 ILEKLQMQTDEVERLKKLQQETIDTLQNKIEFNEKSLRDNLEESQRIIANQQVDIQYKNR 393 Query: 1063 EMQRVSKQLLDS-KQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPM 1121 ++ +S++L S H ++LQ+L +E D Q ++++ +L N + + + S + + Sbjct: 394 QIAELSQKLTQSITDHAKQLQLLAKEADAQRDDIQQ-ELIANSNALENDIQDLKSQLTRI 452 Query: 1122 SDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETL 1181 ++ N V K +E E + Q QS K+N +LQ+ +LE L Sbjct: 453 QNE-NTVLHDENKKLFYDSHSKENRIKEL--EGQIKQNQS-KIN-DLQQ------KLEDL 501 Query: 1182 NTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQ 1241 N +L+ H EQ L ++ +Q +N L++ E +I + D I K Sbjct: 502 N-KLSNH---LDEQNRSLDAQNQQFFNDNKALIAQTEEQEKAIQNLKDLETLHIQLQEKL 557 Query: 1242 HLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQD 1301 L + E + ++ S KY+ L +Q QE+ + Q+ +N++ Sbjct: 558 KLIESEKASLAQTAQQHIEES---EKYKNQLFELQQG-QEKEKRYALDGQMRLKENEVSL 613 Query: 1302 KEEHLRNLQE-KYADVI--NQIEILRSEIEDEKVAFXXXXXXX---XXXXXXXXXDLRTE 1355 K E R E K+ ++ ++ + EIE ++ + Sbjct: 614 KIEVERQQSEIKHNQLLFEEKLSTKQKEIEFIQIQLNSTTSEKVKCLETLSELTKKYEQQ 673 Query: 1356 NQSYKQMQEQSI---LNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELK 1412 + K +QEQ I IN A L++ + +++ + E +Q + Sbjct: 674 KEKLKDLQEQKIQLEAKINNLEALLQEKNNAFEKTSIQIDLLTQESQT-IKEQYNQKVRQ 732 Query: 1413 DSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAIL--RLKMHENA 1470 S + +Y + N+E +++ Q+ EK++ +K SE+A L ++K + Sbjct: 733 ISLQEENISQYAKDNQKLNNELKDLLQEKNNVEKKLLLDLQQKTSEVAQLQQQIKATQKQ 792 Query: 1471 NHYETMQKESEIERVKLIEELNVKITES--VSLNKQVAELNKALEEEVAKTNEMQTALEN 1528 +E Q ++ER KL E +K E L + + + + EE + + E +T L Sbjct: 793 LQFEAQQHNLQVEREKLYMEQQLKTFEQKCQELQQNLIQKEEEQEEFIEQLTEKETMLNE 852 Query: 1529 Q-----EIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDA 1583 Q E+++ +E + +++ S QK + KQ ++ D K +L + Sbjct: 853 QRNQIEELKLQFQKEEDSLNSEILQLQDSLKQKEKQYHIYQKQQKEYTQDKL--KGVLSS 910 Query: 1584 VPRAELDLAMY 1594 + A DL ++ Sbjct: 911 LAEARQDLTIF 921 Score = 103 bits (247), Expect = 4e-20 Identities = 164/842 (19%), Positives = 373/842 (44%), Gaps = 70/842 (8%) Query: 297 KQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEH-LNCQIRQTNKELENKLATMGTE 355 KQ +E + E+E L+ + L KIE E L + ++ + + N+ + + Sbjct: 332 KQILEKLQMQTDEVERLKKLQQETIDTLQNKIEFNEKSLRDNLEESQRIIANQQVDIQYK 391 Query: 356 SKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQ 415 ++ ++ S+K + I+ + A +++ + ++ D +++ N A LE IQ Sbjct: 392 NRQIAELSQKLTQSIT-----DHAKQLQLLAKEADAQ--RDDIQQELIANSNA-LENDIQ 443 Query: 416 SLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDV 475 L L + + K+ I +L+ + +Q+ + + ED+ Sbjct: 444 DLKSQLTRIQNENTVLHDENKKLFYDSHSKENRIKELEGQIKQNQS--KINDLQQKLEDL 501 Query: 476 NEIAKVQEQLKQELNDEIKDV--NVKDLIEKLKSAEEQITQLND--EIDAANKNMIKVKS 531 N+++ ++ + L+ + + + K LI + + E+ I L D + + +K+ Sbjct: 502 NKLSNHLDEQNRSLDAQNQQFFNDNKALIAQTEEQEKAIQNLKDLETLHIQLQEKLKLIE 561 Query: 532 NHKLKLKQM-QKTIDNFSKVSDSNKEIVRLTE-ELHHLSQKVAELEEEKGNLQLHLVDYD 589 + K L Q Q+ I+ K + E+ + E E + L+E + +L++ + Sbjct: 562 SEKASLAQTAQQHIEESEKYKNQLFELQQGQEKEKRYALDGQMRLKENEVSLKIEV---- 617 Query: 590 SGRMIESDVYKKMIEMENLAETRLKAISLLE-------SQKFDLVQELHILQQKYDEVED 642 +S++ + E T+ K I ++ S+K ++ L L +KY++ ++ Sbjct: 618 --ERQQSEIKHNQLLFEEKLSTKQKEIEFIQIQLNSTTSEKVKCLETLSELTKKYEQQKE 675 Query: 643 KLADISQLQSDQVCSEIKSVH--LEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLE 700 KL D+ + Q Q+ ++I ++ L+E+ +A + ++ L+ + + KEQ ++ + Sbjct: 676 KLKDLQE-QKIQLEAKINNLEALLQEKNNAFEKTSIQIDLLTQESQTIKEQYNQKVRQIS 734 Query: 701 NDKEDIMNKLQNYIQENMDLTDKL-EKMSAEK--ISELLAKINHEEQSKIQ---TQFGID 754 +E+I ++ + N +L D L EK + EK + +L K + Q + Q TQ + Sbjct: 735 LQEENISQYAKDNQKLNNELKDLLQEKNNVEKKLLLDLQQKTSEVAQLQQQIKATQKQLQ 794 Query: 755 AKIQERDLYIEN----IESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQ 810 + Q+ +L +E +E +L ++ + L++++ E+ + + + + L E++ Sbjct: 795 FEAQQHNLQVEREKLYMEQQLKTFEQKCQELQQNLIQKEEEQEEFIEQLTEKETMLNEQR 854 Query: 811 KAYSEYTIQ----EDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQ 866 E +Q ED L + + L D + EKQ + + KE + ++ + + Sbjct: 855 NQIEELKLQFQKEEDSLNSEILQLQDSLKQKEKQYHIYQKQQKEYTQ------DKLKGVL 908 Query: 867 ISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIE 926 SL++ +Q K N +E T +T L+ + ++ + L VQ E+E Sbjct: 909 SSLAEARQDLTIFQSKCN----SEINDTHSRT-LQYFQDIMQFSREQKSKLKVQYDNEME 963 Query: 927 DLEIEFNTQIESAI-RDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVE-ELNKM 984 + +T+ E+ + +++ ++ E+ + ++ LE ++ E + + E+N + Sbjct: 964 KYQENISTKFETQLDKERLIMRERESHFNKQISLLEQKVLEQNTRFQEEKQKYQQEINSL 1023 Query: 985 NLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVS 1044 I + +Q + Q + ++ +++ +++ +NQ +QV Y +M+S Sbjct: 1024 EERNITEKIQLNN-EIIQLKNQLLKVESRSARSVEKNQKQLEMVNQNAQKSQVMYANMIS 1082 Query: 1045 DYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKEL-KETKLTFE 1103 D ++KL E+ ++E+Q +++ SK HN + + E +D ++L T T Sbjct: 1083 DIKNKLE------ESEKKELQVLNE--TRSKIHNMKAHLQQIELEDSNEQLAHSTSSTSS 1134 Query: 1104 MN 1105 MN Sbjct: 1135 MN 1136 Score = 70.1 bits (164), Expect = 5e-10 Identities = 158/851 (18%), Positives = 350/851 (41%), Gaps = 93/851 (10%) Query: 154 KDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXED 213 K+N + L+ ++K ++ I DLQ+K +E NK + D Sbjct: 473 KENRIKELEGQIKQNQSKINDLQQK-------LEDLNKLSNHLDEQNRSLDAQNQQFFND 525 Query: 214 TKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSK 273 K + + +E A++ LKD+E+ ++ L+E KL+E+ E + Sbjct: 526 NKALIAQTEEQEKAIQN---------LKDLETLHIQ---LQEKLKLIES-------EKAS 566 Query: 274 LAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEH 333 LAQ +Q L + E++ G + + E++ KIE +E Sbjct: 567 LAQTAQQHIEESEKYKNQLFEL-----QQGQEKEKRYALDGQMRLKE-NEVSLKIE-VER 619 Query: 334 LNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSET 393 +I+ E KL+T +K I + T+ K+K ET Sbjct: 620 QQSEIKHNQLLFEEKLST-----------KQKEIEFIQIQLNSTTSEKVK------CLET 662 Query: 394 LNQDTDK-KINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQL 452 L++ T K + K ++ L+ L + + E ++ EK+ D L + Sbjct: 663 LSELTKKYEQQKEKLKDLQEQKIQLEAKINNLEALLQEKNNAFEKTSIQI---DLLTQES 719 Query: 453 QLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVN--VKDLIEKLKSAEE 510 Q +Q+ + + + E++++ AK ++L EL D +++ N K L+ L+ Sbjct: 720 QTIKEQYNQ--KVRQISLQEENISQYAKDNQKLNNELKDLLQEKNNVEKKLLLDLQQKTS 777 Query: 511 QITQLNDEIDAANKNMIKVKSNHKLKLKQ----MQKTIDNF-SKVSDSNKEIVRLTEE-- 563 ++ QL +I A K + H L++++ M++ + F K + + +++ EE Sbjct: 778 EVAQLQQQIKATQKQLQFEAQQHNLQVEREKLYMEQQLKTFEQKCQELQQNLIQKEEEQE 837 Query: 564 --LHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLES 621 + L++K L E++ ++ + + E + +++++++ + + K + + Sbjct: 838 EFIEQLTEKETMLNEQRNQIEELKLQFQKE---EDSLNSEILQLQDSLKQKEKQYHIYQK 894 Query: 622 QKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVH---LEEQIDALSAS---K 675 Q+ + Q+ L+ + + D++ QS + SEI H L+ D + S K Sbjct: 895 QQKEYTQDK--LKGVLSSLAEARQDLTIFQS-KCNSEINDTHSRTLQYFQDIMQFSREQK 951 Query: 676 KELALVIENLKLDKEQLYGTIKDLENDKED-IMNKLQNYIQENMDLTDKLEKMSAEKISE 734 +L + +N ++ T + + DKE IM + +++ + + L + +K+ + Sbjct: 952 SKLKVQYDNEMEKYQENISTKFETQLDKERLIMRERESHFNKQISLLE--QKVLEQNTRF 1009 Query: 735 LLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICR-LEESIAVMEDRRY 793 K ++++ + I KIQ + I+ ++++L K +SR R +E++ +E Sbjct: 1010 QEEKQKYQQEINSLEERNITEKIQLNNEIIQ-LKNQLLKVESRSARSVEKNQKQLEMVNQ 1068 Query: 794 SLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKEL-- 851 + ++ + + + + E +E +++N + H+ Q +E+E N++L Sbjct: 1069 NAQKSQVMYANMISDIKNKLEESEKKELQVLNETRSKI-HNMKAHLQQIELEDSNEQLAH 1127 Query: 852 --QKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKR 909 + + + + N S +++ N ++ L +++ T ++ E +K Sbjct: 1128 STSSTSSMNKQNSNNDGRSSNNLNNTNNINIDSLQNNTLLQTQRTARLALQKEYEKTMKN 1187 Query: 910 ITHEHQTLI-VQKKKEIEDLEIEFNTQIESAIR--DKKVLNEKYEKNIEYVTQLEAQLQE 966 + + K L++ N+Q +IR K + + I Y ++ Q+ Sbjct: 1188 FQKQEIPVSGNSSNKSNNSLQLS-NSQNNISIRGQSKSMQTNNFVDGINYTLGSTSKYQK 1246 Query: 967 YKNNIENLNMN 977 I N M+ Sbjct: 1247 SPQQITNSKMS 1257 Score = 35.9 bits (79), Expect = 9.2 Identities = 77/452 (17%), Positives = 188/452 (41%), Gaps = 29/452 (6%) Query: 144 VTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXX 203 + +L ++EK+NA +++ ++ ++E+ N+K + I + + Sbjct: 691 INNLEALLQEKNNAFEKTSIQIDLLTQESQTIKEQYNQKVRQISLQEE----NISQYAKD 746 Query: 204 XXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAA 263 +D Q+ +++ + + E +L + I++ ++ E L+ Sbjct: 747 NQKLNNELKDLLQEKNNVEKKLLLDLQQKTSEVAQLQQQIKATQKQL-QFEAQQHNLQVE 805 Query: 264 RFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEI-EEKGSLEIANMT 322 R ++ +E + EQ ++ IE E++T + E++ +E + Sbjct: 806 REKLYMEQQ--LKTFEQKCQELQQNLIQKEEEQEEFIEQLTEKETMLNEQRNQIEELKL- 862 Query: 323 ELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKG---SPLISRKSGRNTA 379 + K+ + L Q++ + K+ E + + K + KG S +R+ Sbjct: 863 QFQKEEDSLNSEILQLQDSLKQKEKQYHIYQKQQKEYTQDKLKGVLSSLAEARQDLTIFQ 922 Query: 380 SKMKSPWSQLSSETLNQDTD-KKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXX 438 SK S + S TL D + ++ + +KL+ +Q N+ +E + ++ +T Sbjct: 923 SKCNSEINDTHSRTLQYFQDIMQFSREQKSKLK--VQYDNEMEKYQENISTKFETQLDKE 980 Query: 439 XXXXXGKDT-LIAQLQLEHQQHMEGPSLIHVGTN--TEDVNEIAKVQEQLKQELNDEIKD 495 +++ Q+ L Q+ +E + +++N + + K +LN+EI Sbjct: 981 RLIMRERESHFNKQISLLEQKVLEQNTRFQEEKQKYQQEINSLEERNITEKIQLNNEI-- 1038 Query: 496 VNVKDLIEKLKSAEEQITQLND-EIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSN 554 + +K+ + K++S + + N +++ N+N K + + + ++ ++ K Sbjct: 1039 IQLKNQLLKVESRSARSVEKNQKQLEMVNQNAQKSQVMYANMISDIKNKLEESEK----- 1093 Query: 555 KEIVRLTE---ELHHLSQKVAELEEEKGNLQL 583 KE+ L E ++H++ + ++E E N QL Sbjct: 1094 KELQVLNETRSKIHNMKAHLQQIELEDSNEQL 1125 >UniRef50_Q22TK4 Cluster: Putative uncharacterized protein; n=1; Tetrahymena thermophila SB210|Rep: Putative uncharacterized protein - Tetrahymena thermophila SB210 Length = 2536 Score = 126 bits (303), Expect = 7e-27 Identities = 294/1482 (19%), Positives = 627/1482 (42%), Gaps = 141/1482 (9%) Query: 159 SVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXE-DTKQQ 217 + L K++I + + D ++ +E Q+ E K K + D K + Sbjct: 305 NALDKKIQIKKAILKDENDQQHEA-QLKEIKEKYRQLVLKSKQQKLAFQKAFKQIDLKGK 363 Query: 218 MTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSL-EEANKLLEAARFEISLEHSKLAQ 276 + +M+E +M + K+E + D+ K ++ SL + K + R + + K+ Sbjct: 364 LNEMREEIHSMIEQEKEESIQNFNDLAQKLLKEKSLNNQFQKEIRKLRSDNQEKDIKIQS 423 Query: 277 ELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKI-ELLEHLN 335 E KQ + + + +++ S TEL K+ EL + ++ Sbjct: 424 INEHTSTVERNQKEFYEKQLKQLQDKINSQTKKYQDEQSKSKQEQTELANKVKELQKQID 483 Query: 336 CQIRQT---NKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSE 392 Q+ + E+E K M T+ + S +K+ I K + K++ + + Sbjct: 484 QQVAEIELFKSEIEEKDLLMKTQEDTIESRNKEIE--IKGKDLKTIQKKLQQ--KEQENN 539 Query: 393 TLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQL 452 +LNQ K +N + + + Q ++L ++ +I EK + K+ L QL Sbjct: 540 SLNQQI--KEAQNSLQQKQEETQKNIENL--QQTIIKEKKSFQIE-------KEKLSQQL 588 Query: 453 QLEHQQHMEGPSLIHVGTN---TEDVNEIAKVQEQLKQELNDEIKDV--NVKDLIEKL-K 506 Q E ++E +L N TE N++ ++Q + + ++IK + + IEK+ K Sbjct: 589 Q-EQLNNVENKTLTIQKLNQTVTELQNKLKQIQLESNNQSGNQIKQIRQEYEQKIEKIQK 647 Query: 507 SAEEQITQLNDE----IDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTE 562 +EQI + E I + K++S K Q QK + K +++ + I L + Sbjct: 648 EQQEQINLIKQENLKAISLLTQKDQKIESLQKQFNLQQQKLAEQIKKQNENQQLIQSLQQ 707 Query: 563 ELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQ 622 L + ++ ++ E+ +LQ + + +E + + + + ++ LK IS E+Q Sbjct: 708 NLKNQNKFNNQIVNEQQDLQ-----ETNNQQLEDEYF--LSTQQKQSQDVLK-IS-KENQ 758 Query: 623 KFDLVQELH-ILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALV 681 D Q+ H I+QQ ++++++ + Q + +++ + S Q + + L Sbjct: 759 FLDQNQDSHFIIQQNNEDIQNEEVN-HQFEQEEIFQNLSSNIQNNQEERDKCANNNNNLG 817 Query: 682 IENLKLDKEQLYGT-----IKDLENDKEDIMNKL--QNYIQENMDLTD------KLEKMS 728 +E+L+++ E ++G IK E + ++ +N+L N+IQ + ++ +++ Sbjct: 818 LEDLEIE-ENVWGNQNNSQIKQEEEEHDEKINQLNQDNFIQAKHERSEFQKEENEIQNKD 876 Query: 729 AEKISE-LLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAV 787 EK E L + N EQS Q Q+ +DL+ ++ E I ++ Sbjct: 877 QEKKYETLFEQNNFVEQSNNQQQY--------QDLFYNTVKQE------EISPIKMQQQN 922 Query: 788 MEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEH- 846 D + +++ + + S Q+ Q ++ +D+ N+ ++ + D++ ++Q + E Sbjct: 923 NFDAVFGNQKQQENIFSNFQQNQNG----SLNKDQNANQ-QLVSNIDQIQQQQHQQNEDI 977 Query: 847 --ENKELQKKNQILLEENQNLQ---ISLSDMQQHYNALVEKANRTD-LAESESTKYQTQL 900 + ++++ +QI ++ +QN Q S +++QQ+ L E + + + ++E + Q Q Sbjct: 978 AINHSQIEELSQIKVQNDQNNQQTSSSQNELQQNNPGLSESSLKDQTIQQNEEFQVQKQQ 1037 Query: 901 RD------LESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQI-ESAIRDKKVLNEKYEKN 953 D L+ + T +Q +KKK+ + E + + +NE + Sbjct: 1038 HDENKLDALDLLMNNNTQTNQPSKKKKKKKKGKTNSNAPVNLFEESTPQNEFINESSQNE 1097 Query: 954 IEYVTQLEAQLQEYKNNIE--NLNMNVEELNKMNLEL-IDKHVQKQQTQSPDYTEQYINE 1010 ++ L++ +Q K+N + L +E ++ N + D + + ++ ++ Q+ N Sbjct: 1098 LKI---LDSSMQSNKSNKDQKQLEKQQDEQSQNNKQAQKDNFYNQFEVKNENWENQFFNT 1154 Query: 1011 INKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQ 1070 K N KD I+ NQ+ NNA + +S ++SK Q K+ N + K Sbjct: 1155 A-KQNIQDAFKD---ISKNQQQNNASKNQNQQIS-FDSKADQSFDKVLN-----NSIDKN 1204 Query: 1071 LLDSKQHNEELQILVR-EQDDQIKELKET--KLTF----EMNIPKTE-GMIISSTIE-PM 1121 L K NE Q +R Q+D ++E KLTF E+N+ + G+ + S E Sbjct: 1205 NLQKKNLNEREQTQIRNNQEDLFSNIQENKQKLTFQNIEELNVEEDAWGIQVESPKEIEQ 1264 Query: 1122 SDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETL 1181 N V +K + ++ +S Q + N +Q+ + IQ + Sbjct: 1265 QGKQNEVPKESIQRDNEHAEIKNDTFQSKLESQSFFQVEQ---NNNVQKIFE--IQNDFF 1319 Query: 1182 NTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQ 1241 + + Q++ + +SK+ + T+N +L + +L + ++ Q L Q Sbjct: 1320 SQINQQNQQDKQQKDEKQESKINKNETQNVQILISDVDLDDNWGTSQPQNDSNDNNLKTQ 1379 Query: 1242 HLAQ---READFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNK 1298 + + +D + ++H+ + S+ + ++ L +++ Q + +K+ ++ + S N+ Sbjct: 1380 AIIESKLNNSDLKSSKHKEELDQSSKQDEFS--LKEQKNAQQIQEHKLDILDLLMSNNNQ 1437 Query: 1299 LQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQS 1358 + + +K +V NQ L E + ++ + Sbjct: 1438 QTGQTVKKKKKSKKAKNVNNQSLNLFEENTPQSTQQNETSQNDIKNLDNSIQSIKQNKEQ 1497 Query: 1359 YKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQ 1418 KQ ++I N ++ N QL S+ + N + ++ Q E K +I Sbjct: 1498 KKQASSENIENNSDLNQQLNTSTQKGSLEKLNEDKQDNCQKEQI--AFEQSENKIIDI-N 1554 Query: 1419 KTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQK 1478 K + I T +E + Q++ + E+ E++ E ++E I +K ++ E Q Sbjct: 1555 KNDQSEIQ-TDNKEELQQENQRIHQIEE--ENVHQESQAE-NIQEIKF----DNIEVNQT 1606 Query: 1479 ESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAK-TNEMQTALENQEIEIVTLN 1537 E+E ++++LIEE+ + I + +Q K L++E + +E NQEI+ T Sbjct: 1607 ENEQKQLELIEEIQIDIEINQQQQRQEEMQIKDLKQENNQIVSEENQINVNQEID--TQV 1664 Query: 1538 DEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKE 1579 ++ N +N +S Q ++ + ++ Q N N++ Sbjct: 1665 EQAINQENDDINQNSNNQIQFTYQEQDNKEQNNQEINEANQQ 1706 Score = 121 bits (292), Expect = 1e-25 Identities = 265/1348 (19%), Positives = 563/1348 (41%), Gaps = 126/1348 (9%) Query: 220 KMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELE 279 K QEN + + ++ L KD + +S++++ + +I++ HS++ +EL Sbjct: 932 KQQENIFSNFQQ--NQNGSLNKDQNANQQLVSNIDQIQQQQHQQNEDIAINHSQI-EELS 988 Query: 280 QXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKG-SLEIANMTELTKKIELLEHLNCQI 338 Q Q+ + + + E+++ L +++ + T I+ E Q Sbjct: 989 QIKVQND-----------QNNQQTSSSQNELQQNNPGLSESSLKDQT--IQQNEEFQVQK 1035 Query: 339 RQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDT 398 +Q ++ + L + + + PSKK +K G+ ++ +P + T + Sbjct: 1036 QQHDENKLDALDLLMNNNTQTNQPSKKKK---KKKKGKTNSN---APVNLFEESTPQNEF 1089 Query: 399 DKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQ 458 + ++NE+ L+ +QS NK D++ + EK KD Q +++++ Sbjct: 1090 INESSQNELKILDSSMQS-NKSNKDQKQL--EKQQDEQSQNNKQAQKDNFYNQFEVKNE- 1145 Query: 459 HMEGPSLIHVGTNTEDV-NEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLND 517 + E N +D +I+K Q+Q N+ K+ N + + K+ + LN+ Sbjct: 1146 NWENQFFNTAKQNIQDAFKDISKNQQQ-----NNASKNQNQQISFDS-KADQSFDKVLNN 1199 Query: 518 EIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIV-RLTEELHHLSQKVAELEE 576 ID N + + +++ Q+ D FS + ++ +++ + EEL+ +EE Sbjct: 1200 SIDKNNLQKKNLNEREQTQIRNNQE--DLFSNIQENKQKLTFQNIEELN--------VEE 1249 Query: 577 EKGNLQLHLVDYDSGRMIESDVYKKMIEMENL-AETRLKAI-SLLESQKFDLVQELHILQ 634 + +Q+ + +++V K+ I+ +N AE + S LESQ F V++ + +Q Sbjct: 1250 DAWGIQVESPKEIEQQGKQNEVPKESIQRDNEHAEIKNDTFQSKLESQSFFQVEQNNNVQ 1309 Query: 635 QKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYG 694 + ++ D + I+Q +Q + K E +I+ + + ++I ++ LD +G Sbjct: 1310 KIFEIQNDFFSQINQ--QNQQDKQQKDEKQESKIN--KNETQNVQILISDVDLDDN--WG 1363 Query: 695 TIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGID 754 T + +ND D K Q I+ ++ +D E++ + + + + Q + Sbjct: 1364 TSQP-QNDSNDNNLKTQAIIESKLNNSDLKSSKHKEELDQSSKQDEFSLKEQKNAQQIQE 1422 Query: 755 AKIQERDLYIENIESELS-----KYKSRICRL--EESIAVMEDRRYSLERKADQLGSYLQ 807 K+ DL + N + K KS+ + +S+ + E+ ++ + + ++ Sbjct: 1423 HKLDILDLLMSNNNQQTGQTVKKKKKSKKAKNVNNQSLNLFEENTPQSTQQNETSQNDIK 1482 Query: 808 EKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQI 867 + +++ + ++++ + +QL + L+K N+ + Q QI Sbjct: 1483 NLDNSIQSIKQNKEQKKQASSENIENNSDLNQQL-NTSTQKGSLEKLNEDKQDNCQKEQI 1541 Query: 868 SLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHE--HQTLIVQKKKEI 925 + +Q N +++ N+ D +E + T + +L+ + +I E HQ + +EI Sbjct: 1542 AF---EQSENKIID-INKNDQSEIQ-TDNKEELQQENQRIHQIEEENVHQESQAENIQEI 1596 Query: 926 EDLEIEFNTQIESAIRDKKVLNE---KYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELN 982 + IE N Q E+ + +++ E E N + Q E Q+++ K EN N V E N Sbjct: 1597 KFDNIEVN-QTENEQKQLELIEEIQIDIEINQQQQRQEEMQIKDLKQ--EN-NQIVSEEN 1652 Query: 983 KMNL-ELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMS 1041 ++N+ + ID V++ Q D Q N N++ +++D + NQ+IN A + Sbjct: 1653 QINVNQEIDTQVEQAINQENDDINQ--NSNNQIQFTYQEQDNKE-QNNQEINEANQQQDT 1709 Query: 1042 MVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLT 1101 + E EN+E++ Q ++ Q + V+ Q+D + L++ + Sbjct: 1710 EEGNIEQTALINQGLAENIEDQSQEQKQEEFKLSQDD------VQGQEDLGENLQDNQKV 1763 Query: 1102 FEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQS 1161 E + + E N++ ++ +EEE V Q QS Sbjct: 1764 QEFKQSEDDETDDKKDQEIQQKSNENIEIIQDNLEDQQEVNQINQEEEL----DVKQNQS 1819 Query: 1162 AKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELR 1221 L+ EL E E N+E+ H V + QINQ++ K EN + L + Sbjct: 1820 -NLDQELNE-------REIQNSEVQNHQDVQENQINQIEKKNSNEQLENQSELQAAQGNK 1871 Query: 1222 SSISSAVDQRGFEIAELWKQHLAQREAD-----FQKTEHELRVQLSAFESKYEQLLDSVQ 1276 S D++ ++ + Q+E D Q ++++V L+ +Q +S++ Sbjct: 1872 HQEFS--DEQNDNQDQINDDQILQQEQDEKIDLSQANNNDIQVDLN--NQIEDQKRNSLK 1927 Query: 1277 SSTQEETNKIVTMEQVTSLQNKLQDKEEH--LRNLQEKYADVINQIEILRSEIEDEKVAF 1334 + E+ + + E +N ++DKEE +++ +E+ ++I Q IE ++ Sbjct: 1928 ENLVEDKQEEILFEDKQE-ENLVEDKEEENLVQDKEEENVEIIQQENENNQNIEQQQ--- 1983 Query: 1335 XXXXXXXXXXXXXXXXDLRTENQSYKQMQE---QSILNINEENAQLKKSSXXXXXXXXXX 1391 + + E Q +KQ QE S NE Q ++ + Sbjct: 1984 DQNVNQFENNQEQNTFEDQNEQQQFKQEQEVLDNSEQIKNEIQQQQQQQTESIDSNQDNQ 2043 Query: 1392 XXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDL 1451 ++ E K LE Q E D +I ++ + + Q + + ++ Q + +++E+ Sbjct: 2044 QLQIKSEEQKELEYELQNE-DDQKIEEQQNNQQVDKAQ-SQQIQHEEQNMNAQLEQLEEN 2101 Query: 1452 TYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKA 1511 E ++ + EN +HY + + ++ K + E E K + N+ Sbjct: 2102 PVELQTNQLESNGQNEENIDHYNLETENLDNQKEKELHE------EQTQEEKPIE--NQQ 2153 Query: 1512 LEEEVAKTNEMQTALENQEIEIVTLNDE 1539 E+E + N+ + ++ ++IEI + E Sbjct: 2154 NEDENQQLNQKENNIQKEDIEITSQTKE 2181 Score = 101 bits (242), Expect = 2e-19 Identities = 179/870 (20%), Positives = 392/870 (45%), Gaps = 96/870 (11%) Query: 475 VNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQ--ITQLN-DEIDAANKNMIKVKS 531 + I + +EQ KQ ++ I+ N DL ++L ++ ++ + +LN D+ D K I + Sbjct: 1488 IQSIKQNKEQKKQASSENIE--NNSDLNQQLNTSTQKGSLEKLNEDKQDNCQKEQIAFEQ 1545 Query: 532 NHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSG 591 + K+ + K ++ S++ NKE EL +Q++ ++EEE V +S Sbjct: 1546 SEN-KIIDINK--NDQSEIQTDNKE------ELQQENQRIHQIEEEN-------VHQESQ 1589 Query: 592 RMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQ 651 ++ IE+ N E K + L+E + D+ E++ QQ+ +E++ K D+ Q + Sbjct: 1590 AENIQEIKFDNIEV-NQTENEQKQLELIEEIQIDI--EINQQQQRQEEMQIK--DLKQ-E 1643 Query: 652 SDQVCSEIKSVHLEEQIDAL--SASKKELALVIENLKLDKEQLYGTIKDLENDKEDI--M 707 ++Q+ SE +++ ++ID A +E + +N + Y + E + ++I Sbjct: 1644 NNQIVSEENQINVNQEIDTQVEQAINQENDDINQNSNNQIQFTYQEQDNKEQNNQEINEA 1703 Query: 708 NKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEE----QSKIQTQFGIDAKIQERDLY 763 N+ Q+ + N++ T + + AE I + + EE Q +Q Q + +Q+ Sbjct: 1704 NQQQDTEEGNIEQTALINQGLAENIEDQSQEQKQEEFKLSQDDVQGQEDLGENLQDNQKV 1763 Query: 764 -----IENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSY--LQEKQKAYS-E 815 E+ E++ K + + E+I +++D +++ +Q+ L KQ + + Sbjct: 1764 QEFKQSEDDETDDKKDQEIQQKSNENIEIIQDNLED-QQEVNQINQEEELDVKQNQSNLD 1822 Query: 816 YTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQ-NLQISLSDMQQ 874 + E E+ N + + +H V E Q+ +IE +N Q +NQ L+ Q N SD Q Sbjct: 1823 QELNEREIQN--SEVQNHQDVQENQINQIEKKNSNEQLENQSELQAAQGNKHQEFSDEQN 1880 Query: 875 HYNALV--------EKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIE 926 + E+ + DL+++ + Q L + + KR + + + L+ K++EI Sbjct: 1881 DNQDQINDDQILQQEQDEKIDLSQANNNDIQVDLNNQIEDQKRNSLK-ENLVEDKQEEIL 1939 Query: 927 DLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNL 986 + + +E ++ ++ +K E+N+E + Q Q + ++ N+N E N+ Sbjct: 1940 FEDKQEENLVEDK-EEENLVQDKEEENVEIIQQENENNQNIEQQ-QDQNVNQFENNQEQN 1997 Query: 987 ELIDKHVQ---KQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMV 1043 D++ Q KQ+ + D +EQ NEI + +Q+ E I NQ +N Q+ + Sbjct: 1998 TFEDQNEQQQFKQEQEVLDNSEQIKNEIQQQ----QQQQTESIDSNQ--DNQQLQ----I 2047 Query: 1044 SDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFE 1103 E K ++ + E+ ++ ++ + Q +D Q ++++Q + + Q+++L+E + + Sbjct: 2048 KSEEQKELEYELQNEDDQKIEEQQNNQQVDKAQ-SQQIQHEEQNMNAQLEQLEENPVELQ 2106 Query: 1104 MNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAK 1163 N ++ G I+ + + N+D K EE+ +E+ + +Q+ Sbjct: 2107 TNQLESNGQN-EENIDHYNLETENLDNQKE---------KELHEEQTQEEKPIENQQNED 2156 Query: 1164 LNTELQECYTKIIQLETLNTELTGHDVVNQ-EQINQLKSKLEQLNTENDNLLSTVAELRS 1222 N +L + I + + T T + + ++ + L N +D+L+ + Sbjct: 2157 ENQQLNQKENNIQKEDIEITSQTKEEKPKELDEDDLLNEDAGWGNQNDDSLIQEDQNWKV 2216 Query: 1223 SISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEE 1282 + ++ ++ ++++ Q++ QK +S +++ S+ QE+ Sbjct: 2217 EENEPQIEKDIQVNDIFENLTEQKD---QKLN----------DSNQDEINCDQHSNNQEQ 2263 Query: 1283 TNKIVTMEQVTSLQNKLQDKEEHLRNLQEK 1312 ++ S N ++KE+ + N+ E+ Sbjct: 2264 QQISENPQKECSNNNLQEEKEDKITNVNEE 2293 Score = 98.3 bits (234), Expect = 2e-18 Identities = 291/1578 (18%), Positives = 657/1578 (41%), Gaps = 142/1578 (8%) Query: 57 AQKCLENAALVSKRIKEHRKATAELLGRPF-VPGISESLANTLKQKEILMEKIKQYKELS 115 AQK L+ +L ++ KE RK ++ + + I+E + + ++ EK Q K+L Sbjct: 390 AQKLLKEKSLNNQFQKEIRKLRSDNQEKDIKIQSINEHTSTVERNQKEFYEK--QLKQLQ 447 Query: 116 KRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNALSVLQVKMKIMETTILDL 175 + ++ + + T L+N +KE + ++++ ++ I + Sbjct: 448 DKINSQTKKYQDEQSKSKQ--------EQTELANKVKELQKQIDQQVAEIELFKSEIEEK 499 Query: 176 QEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDE 235 + ++ IE++NK K+ K QEN ++ + K+ Sbjct: 500 DLLMKTQEDTIESRNKEIEIKGKDLKTIQ----------KKLQQKEQENN-SLNQQIKEA 548 Query: 236 KQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXL 295 + L + E I +L++ + E F+I E KL+Q+L++ L Sbjct: 549 QNSLQQKQEETQKNIENLQQTI-IKEKKSFQI--EKEKLSQQLQEQLNNVENKTLTIQKL 605 Query: 296 AKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTE 355 Q++ + +I+ + + + N + ++ + +I + KE + ++ + E Sbjct: 606 -NQTVTELQNKLKQIQLESNNQSGNQIK-----QIRQEYEQKIEKIQKEQQEQINLIKQE 659 Query: 356 S-KAVSSPSKKGSPLISRKSGRNTASKM------KSPWSQLSSETLNQDTDKKINK--NE 406 + KA+S ++K + S + N + K +Q ++L Q+ K NK N+ Sbjct: 660 NLKAISLLTQKDQKIESLQKQFNLQQQKLAEQIKKQNENQQLIQSLQQNL-KNQNKFNNQ 718 Query: 407 IAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLI 466 I + +Q N ++ EY +S + ++ + Q Q H + I Sbjct: 719 IVNEQQDLQETNNQQLEDEYFLSTQQKQSQDVLKISK-ENQFLDQNQDSHFIIQQNNEDI 777 Query: 467 HVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDA---AN 523 E+VN + QE++ Q L+ I+ N ++ +K + + + EI+ N Sbjct: 778 Q----NEEVNHQFE-QEEIFQNLSSNIQ--NNQEERDKCANNNNNLGLEDLEIEENVWGN 830 Query: 524 KNMIKVKSN---HKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGN 580 +N ++K H K+ Q+ + DNF + E + E+ + Q E + E Sbjct: 831 QNNSQIKQEEEEHDEKINQLNQ--DNFIQAKHERSEFQKEENEIQNKDQ---EKKYETLF 885 Query: 581 LQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEV 640 Q + V+ + + D++ ++ E ++ +++ + ++ + Q+ +I + + Sbjct: 886 EQNNFVEQSNNQQQYQDLFYNTVKQEEISPIKMQQQNNFDAVFGNQKQQENIFSN-FQQN 944 Query: 641 EDKLADISQLQSDQVCSEIKSV----HLEEQIDALSASK-KELALVIENLKLDKEQLYGT 695 ++ + Q + Q+ S I + H + + A++ S+ +EL+ + + +Q + Sbjct: 945 QNGSLNKDQNANQQLVSNIDQIQQQQHQQNEDIAINHSQIEELSQIKVQNDQNNQQTSSS 1004 Query: 696 IKDLENDKEDIM-NKLQNY-IQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGI 753 +L+ + + + L++ IQ+N + + ++ K+ L +N+ Q+ ++ Sbjct: 1005 QNELQQNNPGLSESSLKDQTIQQNEEFQVQKQQHDENKLDALDLLMNNNTQTNQPSKKKK 1064 Query: 754 DAKIQERDLYIE-NIESELSKYKSRICRLEES-IAVMEDRRYSLERKADQLGSYLQEKQK 811 K + + N+ E + I ++ + +++ S + DQ Q+ ++ Sbjct: 1065 KKKKGKTNSNAPVNLFEESTPQNEFINESSQNELKILDSSMQSNKSNKDQKQLEKQQDEQ 1124 Query: 812 AYSEYTIQEDELVNRLAVLMDH--DRVVEKQLLEIEHENKELQK-KNQILLEENQNLQIS 868 + + Q+D N+ V ++ ++ I+ K++ K + Q +NQN QIS Sbjct: 1125 SQNNKQAQKDNFYNQFEVKNENWENQFFNTAKQNIQDAFKDISKNQQQNNASKNQNQQIS 1184 Query: 869 L-SDMQQHYNALVEKA-NRTDLAESE-STKYQTQLRDLESNL-KRITHEHQTLIVQKKKE 924 S Q ++ ++ + ++ +L + + + QTQ+R+ + +L I Q L Q +E Sbjct: 1185 FDSKADQSFDKVLNNSIDKNNLQKKNLNEREQTQIRNNQEDLFSNIQENKQKLTFQNIEE 1244 Query: 925 IEDLEIEFNTQIESA--IRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELN 982 + E + Q+ES I + NE +++I Q + + E KN + +E + Sbjct: 1245 LNVEEDAWGIQVESPKEIEQQGKQNEVPKESI----QRDNEHAEIKN--DTFQSKLESQS 1298 Query: 983 KMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKIN-NAQVSYMS 1041 +E + +VQK D+ Q IN+ N+ + +QKDE+ KIN N + Sbjct: 1299 FFQVEQ-NNNVQKIFEIQNDFFSQ-INQQNQQDK--QQKDEK---QESKINKNETQNVQI 1351 Query: 1042 MVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQD-DQIKELKETKL 1100 ++SD + T++ +N + ++ +++SK +N +L+ +++ DQ + E L Sbjct: 1352 LISDVDLDDNWGTSQPQNDSNDNNLKTQAIIESKLNNSDLKSSKHKEELDQSSKQDEFSL 1411 Query: 1101 TFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQ 1160 + N + + + MS+ NN Q+ + ++++ ++ Sbjct: 1412 KEQKNAQQIQEHKLDILDLLMSN--NN-----------------QQTGQTVKKKKK-SKK 1451 Query: 1161 SAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQ-INQLKSKLEQLNTENDNLLSTVAE 1219 + +N + + + T E + +D+ N + I +K EQ + + ++ Sbjct: 1452 AKNVNNQSLNLFEENTPQSTQQNETSQNDIKNLDNSIQSIKQNKEQKKQASSENIENNSD 1511 Query: 1220 LRSSISSAVDQRGFEIAELWKQHLAQREA-DFQKTEHELRVQLSAFESKYEQLLDSVQSS 1278 L ++++ + E KQ Q+E F+++E+++ + ++ K +Q +Q+ Sbjct: 1512 LNQQLNTSTQKGSLEKLNEDKQDNCQKEQIAFEQSENKI-IDIN----KNDQ--SEIQTD 1564 Query: 1279 TQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQE-KYADV-INQIEILRSEIE--DEKVAF 1334 +EE + +++ ++ + +E N+QE K+ ++ +NQ E + ++E +E Sbjct: 1565 NKEELQQ--ENQRIHQIEEENVHQESQAENIQEIKFDNIEVNQTENEQKQLELIEEIQID 1622 Query: 1335 XXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEE-NAQLKKS---SXXXXXXXXX 1390 DL+ EN + E++ +N+N+E + Q++++ Sbjct: 1623 IEINQQQQRQEEMQIKDLKQENNQI--VSEENQINVNQEIDTQVEQAINQENDDINQNSN 1680 Query: 1391 XXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDE--FENVRQQLVEYEKRI 1448 + E E +Q E+ ++ Q T E I T ++ EN+ Q E ++ Sbjct: 1681 NQIQFTYQEQDNKEQNNQ-EINEANQQQDTEEGNIEQTALINQGLAENIEDQSQEQKQEE 1739 Query: 1449 EDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQ---- 1504 L+ + L + +N E Q E + K +E+ K E++ + + Sbjct: 1740 FKLSQDDVQGQEDLGENLQDNQKVQEFKQSEDDETDDKKDQEIQQKSNENIEIIQDNLED 1799 Query: 1505 VAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDT 1564 E+N+ +EE + Q+ L+ + E N E+ N Q++ ++I+K S Sbjct: 1800 QQEVNQINQEEELDVKQNQSNLDQELNEREIQNSEVQNHQDVQENQINQIEKKNSNEQLE 1859 Query: 1565 KQGRDEQLDNTMNKELLD 1582 Q + ++E D Sbjct: 1860 NQSELQAAQGNKHQEFSD 1877 Score = 93.5 bits (222), Expect = 4e-17 Identities = 227/1173 (19%), Positives = 477/1173 (40%), Gaps = 124/1173 (10%) Query: 473 EDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSN 532 + + K +Q K EL+ ++ N D + E + D+ N I Sbjct: 134 QQIQHANKGGQQKKDELDVVEEESNNCDESQIQNQIREYQNNSKNNYDSLN---INDGFQ 190 Query: 533 HKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGR 592 + + KQ+ + + F S + E+ E +E+K N Q + Sbjct: 191 QQFQQKQVNEKMQGFGGAKQSQSQNAFNQEKKVQKDNLFQEQQEKKQNDQKKQKQKNIEF 250 Query: 593 MIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQ----ELHILQQKYD-EVEDKLADI 647 +E +++ EM+NL L + + +Q +L + Q+ D ++++K A Sbjct: 251 SLE--YVRQISEMQNLLNQEKLEFQLSLQARQNHIQMWEEDLKLRQEALDRQLDEKNALD 308 Query: 648 SQLQSDQ-VCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDI 706 ++Q + + + E Q+ + ++L L + KL ++ + I DL+ ++ Sbjct: 309 KKIQIKKAILKDENDQQHEAQLKEIKEKYRQLVLKSKQQKLAFQKAFKQI-DLKGKLNEM 367 Query: 707 MNKLQNYI-QENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIE 765 ++ + I QE + ++ + + E +N++ Q +I+ + + QE+D+ I+ Sbjct: 368 REEIHSMIEQEKEESIQNFNDLAQKLLKE--KSLNNQFQKEIRK---LRSDNQEKDIKIQ 422 Query: 766 NIESELSKYKSRICRL-EESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELV 824 +I S + E+ + ++D+ S +K Y E+ K+ E T EL Sbjct: 423 SINEHTSTVERNQKEFYEKQLKQLQDKINSQTKK------YQDEQSKSKQEQT----ELA 472 Query: 825 NRLAVLMDH--DRVVEKQLLEIEHENKELQKKNQ--ILLEENQNLQISLSDMQQHYNALV 880 N++ L +V E +L + E E K+L K Q + N+ ++I D++ L Sbjct: 473 NKVKELQKQIDQQVAEIELFKSEIEEKDLLMKTQEDTIESRNKEIEIKGKDLKTIQKKLQ 532 Query: 881 EKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAI 940 +K + + + Q L+ + ++ Q I+++KK + + + + Q++ + Sbjct: 533 QKEQENNSLNQQIKEAQNSLQQKQEETQKNIENLQQTIIKEKKSFQIEKEKLSQQLQEQL 592 Query: 941 RDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMN-VEELNKMNLELIDKHVQKQQTQ 999 + + +K + VT+L+ +L++ + N + N ++++ + + I+K +QK+Q + Sbjct: 593 NNVENKTLTIQKLNQTVTELQNKLKQIQLESNNQSGNQIKQIRQEYEQKIEK-IQKEQQE 651 Query: 1000 SPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLEN 1059 + +Q E K +LL QKD++I +L ++ N Q KLA+ K Sbjct: 652 QINLIKQ---ENLKAISLLTQKDQKIESLQKQFNLQQ-----------QKLAEQIKKQNE 697 Query: 1060 MEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIE 1119 ++ +Q + + L + + N + +V EQ D L+ET N + E ST + Sbjct: 698 NQQLIQSLQQNLKNQNKFNNQ---IVNEQQD----LQET------NNQQLEDEYFLSTQQ 744 Query: 1120 PMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQ-ECYTKIIQL 1178 S D LK+ +E +F+ + + N ++Q E + Sbjct: 745 KQSQDV----------------LKISKENQFLDQNQDSHFIIQQNNEDIQNEEVNHQFEQ 788 Query: 1179 ETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTV--AELRSSISSAVDQRGFEIA 1236 E + L+ + NQE+ ++ + L E+ + V + S I ++ +I Sbjct: 789 EEIFQNLSSNIQNNQEERDKCANNNNNLGLEDLEIEENVWGNQNNSQIKQEEEEHDEKIN 848 Query: 1237 ELWKQHLAQ---READFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQV- 1292 +L + + Q ++FQK E+E +Q E KYE L + Q++ E++N + + Sbjct: 849 QLNQDNFIQAKHERSEFQKEENE--IQNKDQEKKYETLFE--QNNFVEQSNNQQQYQDLF 904 Query: 1293 --TSLQNKLQD-KEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXX 1349 T Q ++ K + N + + Q I + +++ + Sbjct: 905 YNTVKQEEISPIKMQQQNNFDAVFGNQKQQENIFSNFQQNQNGSLNKDQNANQQLVSNID 964 Query: 1350 XDLRTENQSYKQMQEQSILNIN-EENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQ 1408 + + Q ++Q ++ +I + EE +Q+K + + + E + Sbjct: 965 ---QIQQQQHQQNEDIAINHSQIEELSQIKVQNDQNNQQTSSSQNELQQNNPGLSESS-- 1019 Query: 1409 LELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHE 1468 LKD I Q+ E+ + Q ++ + L+ + + +K+ + + K + Sbjct: 1020 --LKDQTI-QQNEEFQVQKQQHDENKLDALDLLMNNNTQTNQPSKKKKKK---KKGKTNS 1073 Query: 1469 NA--NHYETMQKESEIERVKLIEELNV--KITESVSLNKQVAELNKALEEEVAKTNEMQT 1524 NA N +E ++E EL + +S NK +L K +E+ + Q Sbjct: 1074 NAPVNLFEESTPQNEFINESSQNELKILDSSMQSNKSNKDQKQLEKQQDEQSQNNKQAQK 1133 Query: 1525 -------ALENQEIEIVTLNDEITNLQ--------NMVRASSSKIQ-KHVSFASDTKQGR 1568 ++N+ E N N+Q N + ++SK Q + +SF S Q Sbjct: 1134 DNFYNQFEVKNENWENQFFNTAKQNIQDAFKDISKNQQQNNASKNQNQQISFDSKADQSF 1193 Query: 1569 DEQLDNTMNKELLDAVPRAELDLAMYMLHQRDV 1601 D+ L+N+++K L E + +Q D+ Sbjct: 1194 DKVLNNSIDKNNLQKKNLNEREQTQIRNNQEDL 1226 Score = 91.5 bits (217), Expect = 2e-16 Identities = 303/1554 (19%), Positives = 637/1554 (40%), Gaps = 175/1554 (11%) Query: 153 EKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXE 212 EK+ LQ ++ +E L +Q K+N+ + E +NK + Sbjct: 580 EKEKLSQQLQEQLNNVENKTLTIQ-KLNQT--VTELQNKLKQIQLESNNQSGNQIKQIRQ 636 Query: 213 DTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLE---AARFEISL 269 + +Q++ K+Q+ K E + + + KD +I SL++ L + A + + Sbjct: 637 EYEQKIEKIQKEQQEQINLIKQENLKAISLLTQKDQKIESLQKQFNLQQQKLAEQIKKQN 696 Query: 270 EHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIE------EKGSLEIANMTE 323 E+ +L Q L+Q +Q ++ + ++ E E +K S ++ +++ Sbjct: 697 ENQQLIQSLQQNLKNQNKFNNQIVN-EQQDLQETNNQQLEDEYFLSTQQKQSQDVLKISK 755 Query: 324 LTKKIELLEHLNCQIRQTNKELENKLATMGTESKAV----SSPSKKGSPLISRKSGRNTA 379 + ++ + + I+Q N++++N+ E + + SS + + + N Sbjct: 756 ENQFLDQNQDSHFIIQQNNEDIQNEEVNHQFEQEEIFQNLSSNIQNNQEERDKCANNNNN 815 Query: 380 SKMK------SPWSQLSSETLNQDT---DKKIN-------------KNEIAKLEMVIQSL 417 ++ + W ++ + Q+ D+KIN ++E K E IQ Sbjct: 816 LGLEDLEIEENVWGNQNNSQIKQEEEEHDEKINQLNQDNFIQAKHERSEFQKEENEIQ-- 873 Query: 418 NKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEH----QQHMEGPSLIHVGTNTE 473 NKD K + E++ +D ++ E + + G + Sbjct: 874 NKDQEKKYETLFEQNNFVEQSNNQQQYQDLFYNTVKQEEISPIKMQQQNNFDAVFGNQKQ 933 Query: 474 DVNEIAKVQEQLKQELNDEIKDVNV-KDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSN 532 N + Q+ LN KD N + L+ + ++Q Q N++I A N + I+ S Sbjct: 934 QENIFSNFQQNQNGSLN---KDQNANQQLVSNIDQIQQQQHQQNEDI-AINHSQIEELSQ 989 Query: 533 HKLKLKQM-QKTIDNFSKVSDSNKEIVR--LTEELHHLSQKVAELEEEKGNLQLHLVDYD 589 K++ Q Q+T + +++ +N + L ++ +++ +++ +L +D Sbjct: 990 IKVQNDQNNQQTSSSQNELQQNNPGLSESSLKDQTIQQNEEFQVQKQQHDENKLDALDLL 1049 Query: 590 SGRMIESDVYKKMIEMENLAETRLKA-ISLLESQKFDLVQELHILQQKYDEVEDKLADIS 648 +++ K + + +T A ++L E Q I + +E+ K+ D S Sbjct: 1050 MNNNTQTNQPSKKKKKKKKGKTNSNAPVNLFEEST---PQNEFINESSQNEL--KILD-S 1103 Query: 649 QLQSDQVCSEIKSVHLEEQIDALSASKKELA-------LVIENLKLD-------KEQLYG 694 +QS++ + K LE+Q D S + K+ ++N + K+ + Sbjct: 1104 SMQSNKSNKDQKQ--LEKQQDEQSQNNKQAQKDNFYNQFEVKNENWENQFFNTAKQNIQD 1161 Query: 695 TIKDL-ENDKEDIMNKLQNY---IQENMDLT-DKLEKMSAEKISELLAKINHEEQSKIQT 749 KD+ +N +++ +K QN D + DK+ S +K + +N EQ++I+ Sbjct: 1162 AFKDISKNQQQNNASKNQNQQISFDSKADQSFDKVLNNSIDKNNLQKKNLNEREQTQIRN 1221 Query: 750 -QFGIDAKIQE--RDLYIENIES---ELSKYKSRI---CRLEESIAVMEDRRYSLERK-- 798 Q + + IQE + L +NIE E + ++ +E+ E + S++R Sbjct: 1222 NQEDLFSNIQENKQKLTFQNIEELNVEEDAWGIQVESPKEIEQQGKQNEVPKESIQRDNE 1281 Query: 799 -ADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQI 857 A+ Q K ++ S + ++++ V ++ + + Q + + + K+ +++++I Sbjct: 1282 HAEIKNDTFQSKLESQSFFQVEQNNNVQKIFEIQNDFFSQINQQNQQDKQQKDEKQESKI 1341 Query: 858 LLEENQNLQISLSDMQQHYN------------------ALVE-KANRTDLAESESTKYQT 898 E QN+QI +SD+ N A++E K N +DL S+ + Sbjct: 1342 NKNETQNVQILISDVDLDDNWGTSQPQNDSNDNNLKTQAIIESKLNNSDLKSSKHKEELD 1401 Query: 899 QL-RDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNI--- 954 Q + E +LK + Q I + K +I DL + N Q ++ KK K KN+ Sbjct: 1402 QSSKQDEFSLKEQKNAQQ--IQEHKLDILDLLMSNNNQ-QTGQTVKKKKKSKKAKNVNNQ 1458 Query: 955 ------EYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYI 1008 E Q Q + +N+I+NL+ +++ + K N E K + ++ Q + Sbjct: 1459 SLNLFEENTPQSTQQNETSQNDIKNLDNSIQSI-KQNKEQ-KKQASSENIENNSDLNQQL 1516 Query: 1009 NEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVS 1068 N + +L K ++ K +N Q ++ E+K+ +N + E+Q + Sbjct: 1517 NTSTQKGSLEKLNED-------KQDNCQKEQIAFEQS-ENKIIDIN---KNDQSEIQTDN 1565 Query: 1069 KQLLDSKQHNEELQILVRE---QDDQIKELKETKL-TFEMNIPKTEGMIISSTIEPMSDD 1124 K+ L +Q N+ + + E Q+ Q + ++E K E+N + E + IE + D Sbjct: 1566 KEEL--QQENQRIHQIEEENVHQESQAENIQEIKFDNIEVNQTENEQKQLE-LIEEIQID 1622 Query: 1125 ANNVDXXXXXXXXXXXXLKVQEEEEFIQERS---VLQEQSAKLNTELQECYTKIIQLETL 1181 LK QE + + E + V QE ++ + + I Q Sbjct: 1623 IEINQQQQRQEEMQIKDLK-QENNQIVSEENQINVNQEIDTQVEQAINQENDDINQNSNN 1681 Query: 1182 NTELTGHDVVNQEQINQ-LKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWK 1240 + T + N+EQ NQ + +Q +TE N+ T + + DQ + E +K Sbjct: 1682 QIQFTYQEQDNKEQNNQEINEANQQQDTEEGNIEQTALINQGLAENIEDQSQEQKQEEFK 1741 Query: 1241 QHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQ 1300 L+Q + Q+ E +Q + +++Q D +++ + + E + +Q+ L+ Sbjct: 1742 --LSQDDVQGQEDLGE-NLQDNQKVQEFKQSEDDETDDKKDQEIQQKSNENIEIIQDNLE 1798 Query: 1301 DKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYK 1360 D++E + QE+ DV L E+ + ++ + +N S + Sbjct: 1799 DQQEVNQINQEEELDVKQNQSNLDQELNEREIQ-NSEVQNHQDVQENQINQIEKKN-SNE 1856 Query: 1361 QMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEA-KVLELTH------QLELKD 1413 Q++ QS L + N + S ++ E + ++L+ Q++L + Sbjct: 1857 QLENQSELQAAQGNKHQEFSDEQNDNQDQINDDQILQQEQDEKIDLSQANNNDIQVDLNN 1916 Query: 1414 SEIYQKTHEYTITLTQRNDE---FENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENA 1470 QK + L + E FE+ +++ + +K E+L +KE E + + +EN Sbjct: 1917 QIEDQKRNSLKENLVEDKQEEILFEDKQEENLVEDKEEENLVQDKEEENVEIIQQENENN 1976 Query: 1471 NHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQE 1530 + E Q++ + + + +E N E + +Q + + L+ NE+Q + Q+ Sbjct: 1977 QNIE-QQQDQNVNQFENNQEQNT--FEDQNEQQQFKQEQEVLDNSEQIKNEIQQQ-QQQQ 2032 Query: 1531 IEIVTLNDEITNLQNMVRASSSK-IQKHVSFASDTK---QGRDEQLDNTMNKEL 1580 E + N + N Q +++ K ++ + D K Q ++Q+D ++++ Sbjct: 2033 TESIDSNQD--NQQLQIKSEEQKELEYELQNEDDQKIEEQQNNQQVDKAQSQQI 2084 Score = 89.4 bits (212), Expect = 7e-16 Identities = 160/801 (19%), Positives = 351/801 (43%), Gaps = 66/801 (8%) Query: 307 KTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAV--SSPSK 364 +T ++K S + N+ + + L E Q Q N+ +N + + +++ + K Sbjct: 1441 QTVKKKKKSKKAKNVNN--QSLNLFEENTPQSTQQNETSQNDIKNLDNSIQSIKQNKEQK 1498 Query: 365 KGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIA--KLEMVIQSLNKDLV 422 K + + ++ + ++ + + S E LN+D K +IA + E I +NK+ Sbjct: 1499 KQASSENIENNSDLNQQLNTSTQKGSLEKLNEDKQDNCQKEQIAFEQSENKIIDINKNDQ 1558 Query: 423 DKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQ 482 + ++++ ++ + + Q E+ Q ++ + I V + ++ ++ Sbjct: 1559 SEIQTDNKEELQQENQRIHQIEEENVHQESQAENIQEIKFDN-IEVNQTENEQKQLELIE 1617 Query: 483 E-QLKQELNDEIK---DVNVKDLIEKLKS--AEEQITQLNDEIDAANKNMIKVKSNHKLK 536 E Q+ E+N + + ++ +KDL ++ +EE +N EID + I +++ Sbjct: 1618 EIQIDIEINQQQQRQEEMQIKDLKQENNQIVSEENQINVNQEIDTQVEQAINQENDD--- 1674 Query: 537 LKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNL-QLHLVDYDSGRMIE 595 + Q F+ NKE + +E++ +Q + + E+GN+ Q L++ IE Sbjct: 1675 INQNSNNQIQFTYQEQDNKE--QNNQEINEANQ---QQDTEEGNIEQTALINQGLAENIE 1729 Query: 596 SDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKL-ADISQLQSDQ 654 ++ E L++ ++ L D + Q + DE +DK +I Q ++ Sbjct: 1730 DQSQEQKQEEFKLSQDDVQGQEDLGENLQDNQKVQEFKQSEDDETDDKKDQEIQQKSNEN 1789 Query: 655 VCSEIKSVHLEEQIDALSASKKELALVIENLK-LDKEQLYGTIKDLE-NDKEDIMNKLQN 712 + EI +LE+Q + +++E V +N LD+E I++ E + +D+ N Sbjct: 1790 I--EIIQDNLEDQQEVNQINQEEELDVKQNQSNLDQELNEREIQNSEVQNHQDVQENQIN 1847 Query: 713 YIQENMDLTDKLEKMSAEKISELLAKINH-EEQSKIQTQFGIDAKIQERDLYIENIESEL 771 I E + ++LE S + ++ +EQ+ Q Q D +Q+ ++ + +L Sbjct: 1848 QI-EKKNSNEQLENQSELQAAQGNKHQEFSDEQNDNQDQINDDQILQQE----QDEKIDL 1902 Query: 772 SKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLM 831 S+ + +++ + + + +R SL+ + +++KQ+ QE+ LV Sbjct: 1903 SQANNNDIQVDLNNQIEDQKRNSLKE------NLVEDKQEEILFEDKQEENLVE------ 1950 Query: 832 DHDRVVEKQLLEIEHENKEL-QKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAE 890 D+ E + + E EN E+ Q++N E NQN++ + E+ D E Sbjct: 1951 --DKEEENLVQDKEEENVEIIQQEN----ENNQNIEQQQDQNVNQFENNQEQNTFEDQNE 2004 Query: 891 SESTKYQTQLRDLESNLK---RITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLN 947 + K + ++ D +K + + QT + ++ + L+I+ Q E + + Sbjct: 2005 QQQFKQEQEVLDNSEQIKNEIQQQQQQQTESIDSNQDNQQLQIKSEEQKELEYELQNEDD 2064 Query: 948 EKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQY 1007 +K E+ +AQ Q+ ++ +N+N +E+L + +EL Q Q +S E+ Sbjct: 2065 QKIEEQQNNQQVDKAQSQQIQHEEQNMNAQLEQLEENPVEL-----QTNQLESNGQNEEN 2119 Query: 1008 INEIN-KLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQR 1066 I+ N + L QK++E L+++ + + ++ E++ Q K N+++E Sbjct: 2120 IDHYNLETENLDNQKEKE---LHEEQTQEEKPIENQQNEDENQ--QLNQKENNIQKEDIE 2174 Query: 1067 VSKQLLDSKQHNEELQILVRE 1087 ++ Q + K + L+ E Sbjct: 2175 ITSQTKEEKPKELDEDDLLNE 2195 Score = 84.6 bits (200), Expect = 2e-14 Identities = 138/758 (18%), Positives = 318/758 (41%), Gaps = 72/758 (9%) Query: 860 EENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIV 919 ++N+N L DM + + AN+ + + ++ +Y+T + + ++ T++ + L Sbjct: 16 QQNENGFSDLLDMMNEVSKKLPTANKNNQVQEQTNQYKTDMTIQQQQQQQETNQQKWLFY 75 Query: 920 QKKKEIEDLEI-----------EFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQ---LQ 965 K+K + D +I F+ E + + +++ L+ Q Q Sbjct: 76 NKQK-VADFDINEDDLNDGWGDNFSDPEEEEDNQNEGNGNQSNNQVDFSDLLKGQNPSRQ 134 Query: 966 EYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLN---ALLKQ-K 1021 + ++ + +EL+ + E + + Q Q +Y N + LN +Q + Sbjct: 135 QIQHANKGGQQKKDELDVVEEESNNCDESQIQNQIREYQNNSKNNYDSLNINDGFQQQFQ 194 Query: 1022 DEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEEL 1081 +++ Q A+ S + E K+ + E E++ KQ KQ N E Sbjct: 195 QKQVNEKMQGFGGAKQSQSQNAFNQEKKVQKDNLFQEQQEKKQNDQKKQ----KQKNIEF 250 Query: 1082 QI-LVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXX 1140 + VR+ + L + KL F++++ + I E + +D Sbjct: 251 SLEYVRQISEMQNLLNQEKLEFQLSLQARQNH-IQMWEEDLKLRQEALDRQLDEKNALDK 309 Query: 1141 XLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQ------- 1193 K+Q ++ +++ + Q+ A+L E++E Y +++ L++ +L Q Sbjct: 310 --KIQIKKAILKDEND-QQHEAQLK-EIKEKYRQLV-LKSKQQKLAFQKAFKQIDLKGKL 364 Query: 1194 -EQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQK 1252 E ++ S +EQ E+ + +A+ S +Q EI +L + +++ Q Sbjct: 365 NEMREEIHSMIEQEKEESIQNFNDLAQKLLKEKSLNNQFQKEIRKL-RSDNQEKDIKIQS 423 Query: 1253 -TEHELRV---QLSAFESKYEQLLDSVQSSTQE-ETNKIVTMEQVTSLQNKLQDKEEHLR 1307 EH V Q +E + +QL D + S T++ + + + ++ T L NK+++ Sbjct: 424 INEHTSTVERNQKEFYEKQLKQLQDKINSQTKKYQDEQSKSKQEQTELANKVKE------ 477 Query: 1308 NLQEKYADVINQIEILRSEIEDEKVAFXX---XXXXXXXXXXXXXXDLRTENQSYKQMQE 1364 LQ++ + +IE+ +SEIE++ + DL+T + +Q ++ Sbjct: 478 -LQKQIDQQVAEIELFKSEIEEKDLLMKTQEDTIESRNKEIEIKGKDLKTIQKKLQQKEQ 536 Query: 1365 QSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYT 1424 ++ N N Q+K++ + + + +++ +++ ++ Q+ E Sbjct: 537 EN----NSLNQQIKEAQNSLQQKQEETQKNIENLQQTIIKEKKSFQIEKEKLSQQLQEQL 592 Query: 1425 ITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELA-ILRLKMHENANHYETMQKESEIE 1483 + + + + Q + E + +++ + E ++ ++ E E +QKE + E Sbjct: 593 NNVENKTLTIQKLNQTVTELQNKLKQIQLESNNQSGNQIKQIRQEYEQKIEKIQKEQQ-E 651 Query: 1484 RVKLIEELNVK----ITES----VSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVT 1535 ++ LI++ N+K +T+ SL KQ + L E++ K NE Q +++ + + Sbjct: 652 QINLIKQENLKAISLLTQKDQKIESLQKQFNLQQQKLAEQIKKQNENQQLIQSLQQNLKN 711 Query: 1536 ---LNDEITN-LQNMVRASSSKIQKHVSFASDTKQGRD 1569 N++I N Q++ ++ +++ ++ KQ +D Sbjct: 712 QNKFNNQIVNEQQDLQETNNQQLEDEYFLSTQQKQSQD 749 >UniRef50_A0CFQ2 Cluster: Chromosome undetermined scaffold_177, whole genome shotgun sequence; n=6; Eukaryota|Rep: Chromosome undetermined scaffold_177, whole genome shotgun sequence - Paramecium tetraurelia Length = 2953 Score = 126 bits (303), Expect = 7e-27 Identities = 230/1144 (20%), Positives = 485/1144 (42%), Gaps = 102/1144 (8%) Query: 476 NEIAKVQEQLKQELNDEI-KDVNVKDLIEKLKSAEE--QITQLNDEIDAANKNMIKVKSN 532 +++ + +++L ++LN +I K ++ + IE + E+ QI+ L E K + V+ Sbjct: 432 DQLIQTKQKLNEQLNQQIQKPLSSEKQIEFQQDPEKVFQISSLQAECVNLKKQIQDVEQQ 491 Query: 533 HKLKLKQMQKTID---NFSKVSD--SNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVD 587 K LK +K + N ++V S+K+ +++ K +L++E+ LQ L+ Sbjct: 492 RKDDLKSFEKMLGEGVNETQVIGLTSDKQQLQIQVTGFEGQNKCDQLQQEQIALQNQLLQ 551 Query: 588 YDSGRMIESDVYKKMIEMENLAETRLKAISLLESQ---KFDLVQELHILQQKYDEVEDKL 644 + ++++ K E E + I LLE Q D QEL LQQ+ L Sbjct: 552 KNK-QIVDLQDETKQSEKEEQIRGKDNEIKLLEQQVQTAKDQYQELLDLQQQ------NL 604 Query: 645 ADISQLQSDQVCSEIKSVHLEEQI--DALSASKKELALVIENLKLDKEQLYGTIKDLE-- 700 Q +++ + K +H +E++ + + E+ + L +E+L KD E Sbjct: 605 TPGGQ--KEKILQQTKEIHDQEEVINELQQKVETEVPQLQGQLSEAQEKLKDAQKDAELW 662 Query: 701 NDK-EDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQE 759 N K +++ Q +Q N+ +++EK+S+E+ L ++N + K Q ++ +Q Sbjct: 663 NKKYHELLESKQTQVQ-NILAPEEIEKLSSEEAKNALTQLNKQYSDKAQENKELEMVVQH 721 Query: 760 RDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTI- 818 ++++S K + + ++ +V+E + L + L + + + S++ Sbjct: 722 LR---QDLDSSQEKVQQQAKEAQQEKSVLEQQTQLLNNQLKDLVAKEEVQPTRESQWLTF 778 Query: 819 --QEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHY 876 ++ + ++ + + + Q ++ + +E++ K +IL EE + L+I L Sbjct: 779 WKKQYQQLSEKQPEISSTQAGDLQEQQVSQQEREVKPK-EILNEEVELLKIKL------- 830 Query: 877 NALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQI 936 EK N E Q ++D K+ +E +QK + D +I+F T Sbjct: 831 ----EKLNDMQKENEELKAQQILIQDELLKTKQQLNEQLQQQIQKPQG-NDQQIQFQTDP 885 Query: 937 ESAIRDKKVLNE--KYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQ 994 E ++ + E +K I+ V Q + + K+ + L V E + L + +Q Sbjct: 886 EKVLQISSLQAECVNLKKQIQDVEQ--QRKDDLKSFEKMLGEGVNETQVIGLTSDKQQLQ 943 Query: 995 KQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLA-QF 1053 Q + +Q E L L QK+++I+ L + ++ D E KL Q Sbjct: 944 SDLRQLQNKCDQLQQEQIALQDQLLQKNKQIVDLQDETKQSEKEEQIRGKDNEIKLLEQQ 1003 Query: 1054 TTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMI 1113 ++ +E+ + +Q L E++ +E DQ + + + + E +P+ + ++ Sbjct: 1004 VQTAKDQYQELLDLQQQNLTPGGQKEKILQQTKEIHDQEEVINQLQHKVETEVPQLQNLL 1063 Query: 1114 ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYT 1173 + E + N D +QE ++ + + V EQ N +L + Sbjct: 1064 CEAE-EKAKEAQNQADLWNKKYKD------LQEAKQQLVDDYVKPEQIE--NYDLDQAKD 1114 Query: 1174 KIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGF 1233 L LN EL +N EQ+ Q+N N L ++ S + +D Sbjct: 1115 A---LNKLNEELKKQKQINNEQL--------QINENLKNQLKDPQQMLSQAQNEIDDLKL 1163 Query: 1234 EIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVT 1293 + +L K L Q + Q+ +L+ Q+ + +Q +Q T E K++ Q++ Sbjct: 1164 DQIKL-KDELIQAK---QQLNEQLQQQIQKPQGNDQQ----IQFQTDPE--KVL---QIS 1210 Query: 1294 SLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLR 1353 SLQ + + ++ +++++++ D + E + E +E DLR Sbjct: 1211 SLQAQCVNLKKQIQDVEQQRKDDLKSFEKMLGEGVNETQVIGLTSDKQQLQS-----DLR 1265 Query: 1354 TENQSYKQMQEQSILN---INEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLE 1410 Q+Q++ I + ++N Q+ R D E K+LE Q Sbjct: 1266 QLQNKCDQLQQEQIAQQDQLLQKNKQIVDLQDETKQSEKEEQIRGKDNEIKLLEQQVQTA 1325 Query: 1411 LKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENA 1470 + + +T + ++ +++ + E+ I +L + E+E+ L+ ++ E Sbjct: 1326 KDQYQELLDLQQQNLTPGGQKEKILQQTKEIHDQEEVINELQQKVETEVPQLQGQLSEAQ 1385 Query: 1471 NHYETMQKESEIERVKLIEELNVKIT--ESVSLNKQVAEL-NKALEEEVAKTNEMQT--A 1525 + QK++E+ K E L K T +++ +++ +L ++ + + + N+ + A Sbjct: 1386 EKLKDAQKDAELWNKKYHELLESKQTQVQNILAPEEIEKLSSEEAKNALTQLNKQYSDKA 1445 Query: 1526 LENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVP 1585 EN+E+E+V + +L+ + +S K+Q+ A K ++Q +N +L D V Sbjct: 1446 QENKELEMV-----VQHLRQDLDSSQEKVQQQAKEAQQEKSVLEQQ-TQLLNNQLKDLVA 1499 Query: 1586 RAEL 1589 + E+ Sbjct: 1500 KEEV 1503 Score = 118 bits (283), Expect = 2e-24 Identities = 230/1242 (18%), Positives = 538/1242 (43%), Gaps = 115/1242 (9%) Query: 399 DKKIN-KNEIAK--LEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLE 455 +KKIN KN I K L+ V Q +DL + +I + Q QL Sbjct: 3 NKKINQKNIILKDQLQEVEQQRQEDLKSFKEIIGNGADQQCIADLVTQKQKLQTDQRQLL 62 Query: 456 HQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQL 515 Q + LI + NE+ K+ QLK + D+I+ +++ E LK + +I L Sbjct: 63 IQINKLQEELIQ---QQNENNEMKKMVNQLKNQQQDQIQ---IQE-NEVLKIRQNEIDDL 115 Query: 516 N-DEIDAANKNM-IKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAE 573 D+I ++ + K K N +L +Q+QK + S+++ + ++ + Q ++ Sbjct: 116 KLDQIKLKDELIQTKQKLNEQLN-QQIQKPL--------SSEKQIEFQQDPEKVFQ-ISS 165 Query: 574 LEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHIL 633 L+ E NL+ + D + R + ++KM+ E + ET++ L S K L +L L Sbjct: 166 LQAECVNLKKQIQDVEQQRKDDLKSFEKMLG-EGVNETQVIG---LTSDKQQLQSDLRQL 221 Query: 634 QQKYDEV-EDKLADISQL--QSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKE 690 Q K D++ ++++A QL ++ Q+ E+ + + E+ L+ + ++ K+ Sbjct: 222 QNKCDQLQQEQIALQDQLLQKNKQIVDLQDETKQSEKEEQIRGKDNEIKLLEQQVQTAKD 281 Query: 691 QLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQ 750 Q Y + DL+ + + +Q+ ++ D+ E++ ++ H+ ++++ Sbjct: 282 Q-YQELLDLQQQNLTPGGQKEKILQQTKEIHDQ---------EEVINQLQHKVETEVPQL 331 Query: 751 FGIDAKIQERDLYIENIESEL--SKYK----SRICRLEESIAVMEDRRYSLERKADQLGS 804 + + +E+ +N +++L KYK ++ +++ + + Y L++ D L Sbjct: 332 QNLLCEAEEKAKEAQN-QADLWNKKYKDLQEAKQQLVDDYVKPEQIENYDLDQAKDALNK 390 Query: 805 YLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQN 864 + E+ K + ++ ++ NR + + + + +L +I+ +++ +Q K ++ + NQ Sbjct: 391 -MNEELKKQKQINNEQLQIHNR-CLHETQNEIDDLKLDQIKLKDQLIQTKQKLNEQLNQQ 448 Query: 865 LQISLSDMQQ-HYNALVEKANRTDLAESESTKYQTQLRDLESNLK-------RITHE--H 914 +Q LS +Q + EK + ++E + Q++D+E K ++ E + Sbjct: 449 IQKPLSSEKQIEFQQDPEKVFQISSLQAECVNLKKQIQDVEQQRKDDLKSFEKMLGEGVN 508 Query: 915 QTLIVQKKKEIEDLEIE---FNTQIE-SAIRDKKVL--NEKYEKNIEYV--------TQL 960 +T ++ + + L+I+ F Q + ++ +++ N+ +KN + V ++ Sbjct: 509 ETQVIGLTSDKQQLQIQVTGFEGQNKCDQLQQEQIALQNQLLQKNKQIVDLQDETKQSEK 568 Query: 961 EAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQK-----------QQTQSPDYTEQYIN 1009 E Q++ N I+ L V+ EL+D Q QQT+ E+ IN Sbjct: 569 EEQIRGKDNEIKLLEQQVQTAKDQYQELLDLQQQNLTPGGQKEKILQQTKEIHDQEEVIN 628 Query: 1010 EI-NKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENM--EEEMQR 1066 E+ K+ + Q ++ +K+ +AQ Y L T+++N+ EE+++ Sbjct: 629 ELQQKVETEVPQLQGQLSEAQEKLKDAQKDAELWNKKYHELLESKQTQVQNILAPEEIEK 688 Query: 1067 VS------------KQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMII 1114 +S KQ D Q N+EL+++V+ + +E K+ + + E ++ Sbjct: 689 LSSEEAKNALTQLNKQYSDKAQENKELEMVVQHLRQDLDSSQE-KVQQQAKEAQQEKSVL 747 Query: 1115 SSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTK 1174 + +++ ++ ++++ Q E S+ +LQE Sbjct: 748 EQQTQLLNNQLKDLVAKEEVQPTRESQWLTFWKKQYQQLSEKQPEISSTQAGDLQE---- 803 Query: 1175 IIQLETLNTELTGHDVVNQEQINQLKSKLEQLN---TENDNLLSTVAELRSSISSAVDQR 1231 Q+ E+ +++N E++ LK KLE+LN EN+ L + ++ + Q Sbjct: 804 -QQVSQQEREVKPKEILN-EEVELLKIKLEKLNDMQKENEELKAQQILIQDELLKTKQQL 861 Query: 1232 GFEI-AELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTME 1290 ++ ++ K ++ FQ T+ E +Q+S+ +++ L +Q Q+ + + + E Sbjct: 862 NEQLQQQIQKPQGNDQQIQFQ-TDPEKVLQISSLQAECVNLKKQIQDVEQQRKDDLKSFE 920 Query: 1291 QVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXX 1350 ++ + + + L + +++ + Q++ +++ E++A Sbjct: 921 KMLG-EGVNETQVIGLTSDKQQLQSDLRQLQNKCDQLQQEQIALQDQLLQKNKQIVDLQD 979 Query: 1351 DLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLE 1410 + + + + + + + + E+ Q K + K+L+ T ++ Sbjct: 980 ETKQSEKEEQIRGKDNEIKLLEQQVQTAKDQYQELLDLQQQNLTPGGQKEKILQQTKEIH 1039 Query: 1411 LKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENA 1470 ++ I Q H+ + Q + ++ E + + DL +K +L + ++ ++ Sbjct: 1040 DQEEVINQLQHKVETEVPQLQNLLCEAEEKAKEAQNQ-ADLWNKKYKDLQEAKQQLVDDY 1098 Query: 1471 NHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQE 1530 E ++ + + +LN ++ + +N + ++N+ L+ ++ +M + +N E Sbjct: 1099 VKPEQIENYDLDQAKDALNKLNEELKKQKQINNEQLQINENLKNQLKDPQQMLSQAQN-E 1157 Query: 1531 IEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQL 1572 I+ + L D+I +++A ++ + + QG D+Q+ Sbjct: 1158 IDDLKL-DQIKLKDELIQA-KQQLNEQLQQQIQKPQGNDQQI 1197 Score = 116 bits (280), Expect = 4e-24 Identities = 270/1464 (18%), Positives = 613/1464 (41%), Gaps = 116/1464 (7%) Query: 143 DVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQE--KINEKDQIIEAKNKATTXXXXXX 200 D+ L N + LQ ++ I+DLQ+ K +EK++ I K+ Sbjct: 217 DLRQLQNKCDQLQQEQIALQDQLLQKNKQIVDLQDETKQSEKEEQIRGKDNEIKLLEQQV 276 Query: 201 XXXXXXXXXXXEDTKQQMTK--MQENFIAMEAEWKDEKQ---RLLKDIESKDVRISSLE- 254 + +Q +T +E + E D+++ +L +E++ ++ +L Sbjct: 277 QTAKDQYQELLDLQQQNLTPGGQKEKILQQTKEIHDQEEVINQLQHKVETEVPQLQNLLC 336 Query: 255 EANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKG 314 EA + + A+ + L + K ++L++ + ++ + + ++ E Sbjct: 337 EAEEKAKEAQNQADLWNKKY-KDLQEAKQQLVDDYVKPEQIENYDLDQAKDALNKMNE-- 393 Query: 315 SLEIANMTELTKKIELLEHLNCQIRQTNKELEN-KLATMGTESKAVSSPSKKGSPLISRK 373 E+ ++ + +L H C + +T E+++ KL + + + + + K L Sbjct: 394 --ELKKQKQINNE-QLQIHNRC-LHETQNEIDDLKLDQIKLKDQLIQTKQKLNEQL---- 445 Query: 374 SGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDT 433 +++ P S QD +K +I+ L+ +L K + D E KD Sbjct: 446 -----NQQIQKPLSSEKQIEFQQDPEKVF---QISSLQAECVNLKKQIQDVEQ--QRKDD 495 Query: 434 XXXXXXXXXXG-KDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDE 492 G +T + L + QQ I V T E N+ ++Q++ N Sbjct: 496 LKSFEKMLGEGVNETQVIGLTSDKQQLQ-----IQV-TGFEGQNKCDQLQQEQIALQNQL 549 Query: 493 I-KDVNVKDLIEKLKSAE--EQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTID---N 546 + K+ + DL ++ K +E EQI ++EI + + K ++ L Q+ + Sbjct: 550 LQKNKQIVDLQDETKQSEKEEQIRGKDNEIKLLEQQVQTAKDQYQELLDLQQQNLTPGGQ 609 Query: 547 FSKVSDSNKEIVRLTEELHHLSQKV-AELEEEKGNL---QLHLVDYDSGRMIESDVYKKM 602 K+ KEI E ++ L QKV E+ + +G L Q L D + + Y ++ Sbjct: 610 KEKILQQTKEIHDQEEVINELQQKVETEVPQLQGQLSEAQEKLKDAQKDAELWNKKYHEL 669 Query: 603 IEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQS--DQVCSEIK 660 +E + + A E +K + + L Q + DK + +L+ + ++ Sbjct: 670 LESKQTQVQNILAPE--EIEKLSSEEAKNALTQLNKQYSDKAQENKELEMVVQHLRQDLD 727 Query: 661 SVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDL 720 S + Q A A ++E +++ + +L QL + E L + ++ L Sbjct: 728 SSQEKVQQQAKEA-QQEKSVLEQQTQLLNNQLKDLVAKEEVQPTRESQWLTFWKKQYQQL 786 Query: 721 TDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICR 780 ++K ++S+ + +L + +++ +++ + ++ +++ + +E + +++ K + Sbjct: 787 SEKQPEISSTQAGDLQEQQVSQQEREVKPKEILNEEVELLKIKLEKL-NDMQKENEEL-- 843 Query: 781 LEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQED-ELVNRLAVLMDHDRVVEK 839 + I + ++ + ++ +QL +Q+ Q + Q D E V +++ L ++K Sbjct: 844 KAQQILIQDELLKTKQQLNEQLQQQIQKPQGNDQQIQFQTDPEKVLQISSLQAECVNLKK 903 Query: 840 QLLEIEHENKELQKKNQILLEE--NQNLQISL-SDMQQHYNALVEKANRTDLAESESTKY 896 Q+ ++E + K+ K + +L E N+ I L SD QQ + L + N+ D + E Sbjct: 904 QIQDVEQQRKDDLKSFEKMLGEGVNETQVIGLTSDKQQLQSDLRQLQNKCDQLQQEQIAL 963 Query: 897 QTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEY 956 Q QL L+ N + + + +T +K+++I + E +E ++ K ++Y++ ++ Sbjct: 964 QDQL--LQKNKQIVDLQDETKQSEKEEQIRGKDNEIKL-LEQQVQTAK---DQYQELLD- 1016 Query: 957 VTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNA 1016 L+ Q E + +E++ E+I++ K +T+ P Q N + + Sbjct: 1017 ---LQQQNLTPGGQKEKILQQTKEIHDQE-EVINQLQHKVETEVP----QLQNLLCEAEE 1068 Query: 1017 LLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQ 1076 K+ + N+K + Q + +V DY L+ ++ + +++++L KQ Sbjct: 1069 KAKEAQNQADLWNKKYKDLQEAKQQLVDDYVKPEQIENYDLDQAKDALNKLNEELKKQKQ 1128 Query: 1077 -HNEELQILVREQDDQIKELKE--TKLTFEMNIPKTEGMIISSTIEPMSDDANN-VDXXX 1132 +NE+LQI +Q+K+ ++ ++ E++ K + + + + N + Sbjct: 1129 INNEQLQIN-ENLKNQLKDPQQMLSQAQNEIDDLKLDQIKLKDELIQAKQQLNEQLQQQI 1187 Query: 1133 XXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVN 1192 ++ Q + E + + S LQ Q L ++Q+ + ++ G V N Sbjct: 1188 QKPQGNDQQIQFQTDPEKVLQISSLQAQCVNLKKQIQDVEQQRKDDLKSFEKMLGEGV-N 1246 Query: 1193 QEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQ---RGFEIAELWKQ-HLAQREA 1248 + Q+ L S +QL ++ L + +L+ + DQ + +I +L + +++E Sbjct: 1247 ETQVIGLTSDKQQLQSDLRQLQNKCDQLQQEQIAQQDQLLQKNKQIVDLQDETKQSEKEE 1306 Query: 1249 DFQKTEHELRV---QLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEH 1305 + ++E+++ Q+ + +Y++LLD Q + K E++ ++ D+EE Sbjct: 1307 QIRGKDNEIKLLEQQVQTAKDQYQELLDLQQQNLTPGGQK----EKILQQTKEIHDQEEV 1362 Query: 1306 LRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQ 1365 + LQ+K + Q++ SE +++ +T+ Q+ +E Sbjct: 1363 INELQQKVETEVPQLQGQLSEAQEKLKDAQKDAELWNKKYHELLESKQTQVQNILAPEEI 1422 Query: 1366 SILNINE-ENA--QLKKSSXXXXXXXXXXXXRV-------NDAEAKVLELTHQLELKDSE 1415 L+ E +NA QL K V + ++ KV + + + + S Sbjct: 1423 EKLSSEEAKNALTQLNKQYSDKAQENKELEMVVQHLRQDLDSSQEKVQQQAKEAQQEKSV 1482 Query: 1416 IYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIE----DLTYEKESELAILRLKMHE--- 1468 + Q+T L + E RQ++++ + +++ D ++ +L+ + ++ Sbjct: 1483 LEQQTQLLNNQLKDLVAKEEVQRQEILDLKNKLDQENADFWKKQYQQLSEKQPEISSTQA 1542 Query: 1469 -NANHYETMQKESEIERVKLIEE----LNVKITESVSLNKQVAELNKA---LEEEVAKTN 1520 + + Q+E E++ +++ E L +K+ + + K+ EL +++E+ KT Sbjct: 1543 GDLQEQQVSQQEREVKPKEILNEEVELLKIKLEKLNDMQKENEELKAQQILIQDELLKTK 1602 Query: 1521 EMQTALENQEIEIVTLNDEITNLQ 1544 + Q+I+ ND+ Q Sbjct: 1603 QQLNEQLQQQIQKPQGNDQQIQFQ 1626 Score = 92.7 bits (220), Expect = 8e-17 Identities = 202/1110 (18%), Positives = 479/1110 (43%), Gaps = 97/1110 (8%) Query: 525 NMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLH 584 N K+ + + Q+Q+ + S KEI+ + Q +A+L +K LQ Sbjct: 2 NNKKINQKNIILKDQLQEVEQQRQEDLKSFKEIIGNGAD----QQCIADLVTQKQKLQ-- 55 Query: 585 LVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQ--ELHILQQKYDEVED 642 D + + + +++I+ +N K ++ L++Q+ D +Q E +L+ + +E++D Sbjct: 56 -TDQRQLLIQINKLQEELIQQQNENNEMKKMVNQLKNQQQDQIQIQENEVLKIRQNEIDD 114 Query: 643 KLADISQLQSDQVCSEIK-SVHLEEQIDALSASKKEL--------ALVIENLKLDKEQLY 693 D +L+ + + ++ K + L +QI +S+K++ I +L+ + L Sbjct: 115 LKLDQIKLKDELIQTKQKLNEQLNQQIQKPLSSEKQIEFQQDPEKVFQISSLQAECVNLK 174 Query: 694 GTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMS-AEKISELLAKINHEEQSKIQTQFG 752 I+D+E ++D + + + E ++ T + S +++ L ++ ++ Q Q Sbjct: 175 KQIQDVEQQRKDDLKSFEKMLGEGVNETQVIGLTSDKQQLQSDLRQLQNKCDQLQQEQIA 234 Query: 753 IDAKIQERDLYIENIESEL--SKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQE-- 808 + ++ +++ I +++ E S+ + +I + I ++E + + + + +L Q+ Sbjct: 235 LQDQLLQKNKQIVDLQDETKQSEKEEQIRGKDNEIKLLEQQVQTAKDQYQELLDLQQQNL 294 Query: 809 -----KQKAYSEYTI--QEDELVNRLAVLMDHD-RVVEKQLLEIEHENKELQKKNQILLE 860 K+K + ++E++N+L ++ + ++ L E E + KE Q + + + Sbjct: 295 TPGGQKEKILQQTKEIHDQEEVINQLQHKVETEVPQLQNLLCEAEEKAKEAQNQADLWNK 354 Query: 861 ENQNLQISLSDMQQHYNALVEKANRT-DLAESESTKYQTQLRDLESNLKRITHEHQTLIV 919 + ++LQ + + Y + N D A+ K +L+ + H + Sbjct: 355 KYKDLQEAKQQLVDDYVKPEQIENYDLDQAKDALNKMNEELKKQKQINNEQLQIHNRCLH 414 Query: 920 QKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVE 979 + + EI+DL+++ + I+ K+ LNE+ + I+ E Q+ E++ + E V Sbjct: 415 ETQNEIDDLKLDQIKLKDQLIQTKQKLNEQLNQQIQKPLSSEKQI-EFQQDPE----KVF 469 Query: 980 ELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSY 1039 +++ + E ++ K+Q Q D +Q +++ +L + E + + Q+ Sbjct: 470 QISSLQAECVN---LKKQIQ--DVEQQRKDDLKSFEKMLGEGVNETQVIGLTSDKQQLQI 524 Query: 1040 MSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLD----SKQHNEELQILVREQDDQIKEL 1095 + ++K Q + ++ ++ + +KQ++D +KQ +E QI R +D++IK L Sbjct: 525 QVTGFEGQNKCDQLQQEQIALQNQLLQKNKQIVDLQDETKQSEKEEQI--RGKDNEIKLL 582 Query: 1096 KETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQE-R 1154 ++ ++ K + E + N+ ++ ++EE I E + Sbjct: 583 EQ-----QVQTAKDQYQ------ELLDLQQQNLTPGGQKEKILQQTKEIHDQEEVINELQ 631 Query: 1155 SVLQEQSAKLNTELQECYTKIIQLETLNTELTG---HDVV--NQEQINQLKSKLEQLNTE 1209 ++ + +L +L E K+ + + EL H+++ Q Q+ + + E Sbjct: 632 QKVETEVPQLQGQLSEAQEKLKDAQK-DAELWNKKYHELLESKQTQVQNILAPEEIEKLS 690 Query: 1210 NDNLLSTVAELRSSIS-SAVDQRGFE-IAELWKQHLAQREADFQKTEHELRVQLSAFESK 1267 ++ + + +L S A + + E + + +Q L + Q+ E + + S E + Sbjct: 691 SEEAKNALTQLNKQYSDKAQENKELEMVVQHLRQDLDSSQEKVQQQAKEAQQEKSVLEQQ 750 Query: 1268 YEQLLDSVQS-STQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSE 1326 + L + ++ +EE + +T + + Q E + A + + ++ + E Sbjct: 751 TQLLNNQLKDLVAKEEVQPTRESQWLTFWKKQYQQLSEKQPEISSTQAGDLQEQQVSQQE 810 Query: 1327 IEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQ---EQSILNINEE-NAQLKKSSX 1382 E + D++ EN+ K Q + +L ++ N QL++ Sbjct: 811 REVKPKEILNEEVELLKIKLEKLNDMQKENEELKAQQILIQDELLKTKQQLNEQLQQQIQ 870 Query: 1383 XXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLV 1442 + D E KVL+++ L+ + + ++ + QR D+ ++ + L Sbjct: 871 KPQGNDQQIQFQ-TDPE-KVLQIS-SLQAECVNLKKQIQDVE---QQRKDDLKSFEKMLG 924 Query: 1443 E--YEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVS 1500 E E ++ LT +K+ L+ + + N + +Q+ E++ L ++L K + V Sbjct: 925 EGVNETQVIGLTSDKQQ----LQSDLRQLQNKCDQLQQ----EQIALQDQLLQKNKQIVD 976 Query: 1501 LNKQVAELNKALEEEV-AKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVS 1559 L + + K EE++ K NE++ LE Q + T D+ L ++ + + + + Sbjct: 977 LQDETKQSEK--EEQIRGKDNEIK-LLEQQ---VQTAKDQYQELLDLQQQNLTPGGQKEK 1030 Query: 1560 FASDTKQGRD-EQLDNTMNKELLDAVPRAE 1588 TK+ D E++ N + ++ VP+ + Sbjct: 1031 ILQQTKEIHDQEEVINQLQHKVETEVPQLQ 1060 Score = 85.0 bits (201), Expect = 2e-14 Identities = 138/748 (18%), Positives = 321/748 (42%), Gaps = 43/748 (5%) Query: 858 LLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTL 917 L+ + Q LQ + N L E+ + +E K QL++ + + +I E++ L Sbjct: 47 LVTQKQKLQTDQRQLLIQINKLQEELIQQQNENNEMKKMVNQLKNQQQDQIQI-QENEVL 105 Query: 918 IVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMN 977 + ++ EI+DL+++ + I+ K+ LNE+ + I+ E Q++ ++ + ++ Sbjct: 106 KI-RQNEIDDLKLDQIKLKDELIQTKQKLNEQLNQQIQKPLSSEKQIEFQQDPEKVFQIS 164 Query: 978 VEELNKMNLELIDKHVQKQQTQSPDYTEQYINE-INKLNALLKQKDEEIIA--LNQKINN 1034 + +NL+ + V++Q+ E+ + E +N+ + D++ + L Q N Sbjct: 165 SLQAECVNLKKQIQDVEQQRKDDLKSFEKMLGEGVNETQVIGLTSDKQQLQSDLRQLQNK 224 Query: 1035 AQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEE--LQILVREQDDQI 1092 ++ + +L Q ++ ++++E ++ K+ + NE L+ V+ DQ Sbjct: 225 CDQLQQEQIA-LQDQLLQKNKQIVDLQDETKQSEKEEQIRGKDNEIKLLEQQVQTAKDQY 283 Query: 1093 KELKETKLTFEMNI-PKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLK--VQEEEE 1149 +EL + + + N+ P + I + + D ++ L+ + E EE Sbjct: 284 QELLDLQ---QQNLTPGGQKEKILQQTKEIHDQEEVINQLQHKVETEVPQLQNLLCEAEE 340 Query: 1150 FIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVN-QEQINQLKSKLEQLNT 1208 +E + K +LQE +++ ++ +D+ ++ +N++ +L++ Sbjct: 341 KAKEAQNQADLWNKKYKDLQEAKQQLVDDYVKPEQIENYDLDQAKDALNKMNEELKKQKQ 400 Query: 1209 ENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKY 1268 N+ L + +D + +L K L Q + QK +L Q+ Sbjct: 401 INNEQLQIHNRCLHETQNEIDDLKLDQIKL-KDQLIQTK---QKLNEQLNQQIQ------ 450 Query: 1269 EQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIE 1328 + L Q Q++ K+ Q++SLQ + + ++ +++++++ D + E + E Sbjct: 451 KPLSSEKQIEFQQDPEKVF---QISSLQAECVNLKKQIQDVEQQRKDDLKSFEKMLGEGV 507 Query: 1329 DEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILN--INEENAQLKKSSXXXXX 1386 +E + +N+ + QEQ L + ++N Q+ Sbjct: 508 NETQVIGLTSDKQQLQIQVTGFE--GQNKCDQLQQEQIALQNQLLQKNKQIVDLQDETKQ 565 Query: 1387 XXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEK 1446 R D E K+LE Q + + +T + ++ +++ + E+ Sbjct: 566 SEKEEQIRGKDNEIKLLEQQVQTAKDQYQELLDLQQQNLTPGGQKEKILQQTKEIHDQEE 625 Query: 1447 RIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKIT--ESVSLNKQ 1504 I +L + E+E+ L+ ++ E + QK++E+ K E L K T +++ ++ Sbjct: 626 VINELQQKVETEVPQLQGQLSEAQEKLKDAQKDAELWNKKYHELLESKQTQVQNILAPEE 685 Query: 1505 VAEL-NKALEEEVAKTNEMQT--ALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFA 1561 + +L ++ + + + N+ + A EN+E+E+V + +L+ + +S K+Q+ A Sbjct: 686 IEKLSSEEAKNALTQLNKQYSDKAQENKELEMV-----VQHLRQDLDSSQEKVQQQAKEA 740 Query: 1562 SDTKQGRDEQLDNTMNKELLDAVPRAEL 1589 K ++Q +N +L D V + E+ Sbjct: 741 QQEKSVLEQQ-TQLLNNQLKDLVAKEEV 767 Score = 76.2 bits (179), Expect = 7e-12 Identities = 112/524 (21%), Positives = 240/524 (45%), Gaps = 42/524 (8%) Query: 596 SDVYKKMIEMENLAET-RLKAISLLESQKFDLVQEL---HILQQKYDEVEDKLADISQLQ 651 S+ +K+ + + AE K LLES++ + L I + +E ++ L +++ Sbjct: 2353 SEAQEKLKDAQKDAELWNKKYHELLESKQTQVQNILAPEEIEKLSSEEAKNALTQLNKQY 2412 Query: 652 SD--QVCSEIKSV--HLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIM 707 SD Q E++ V HL + +D+ S++++ + + +K L + L N +D++ Sbjct: 2413 SDKAQENKELEMVVQHLRQDLDS---SQEKVQQQAKEAQQEKSVLEQQTQLLNNQLKDLV 2469 Query: 708 NKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFG--IDAKIQERDLYIE 765 K + QE +DL +KL++ +A+ + +++ ++ TQ G + ++ +++ ++ Sbjct: 2470 AKEEVQRQEILDLKNKLDQENADFWKKQYQQLSEKQPEISSTQAGDLQEQQVSQQEREVK 2529 Query: 766 NIESELSKYKSRICRLEESIAVMEDRRYSLE--------RKADQLGSYLQEKQKAYSEYT 817 E + IC+ + + + RY + + ++L +Q+ Q + Sbjct: 2530 PKEILNEERNQMICK--KKMKNWKHNRYQFKMNYSKLSNSQMNKLQQQIQKPQGNDQQIQ 2587 Query: 818 IQED-ELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEE--NQNLQISL-SDMQ 873 Q D E V +++ L ++KQ+ ++E + K+ K + +L E N+ I L SD Q Sbjct: 2588 FQTDPEKVLQISSLQAECVNLKKQIQDVEQQRKDDLKSFEKMLGEGVNETQVIGLTSDKQ 2647 Query: 874 QHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFN 933 Q + L + N+ D + E Q QL L+ N + + + +T +K+++I + E Sbjct: 2648 QLQSDLRQLQNKCDQLQQEQIALQNQL--LQKNKQIVDLQDETKQSEKEEQIRGKDNEIK 2705 Query: 934 TQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHV 993 +E ++ K ++Y++ ++ L+ Q E + +E++ E+I++ Sbjct: 2706 L-LEQQVQTAK---DQYQELLD----LQQQNLTPGGQKEKILQQTKEIHDQE-EVINELQ 2756 Query: 994 QKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQF 1053 QK +T+ P Q KL QKD E+ N+K + S + V + + Sbjct: 2757 QKVETEVPQLQGQLSEAQEKLKD--AQKDAEL--WNKKYHELLESKQTQVQNILAPEEIE 2812 Query: 1054 TTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKE 1097 E + + +++KQ D Q N+EL+++V+ + +E Sbjct: 2813 KLSSEEAKNALTQLNKQYSDKAQENKELEMVVQHLRQDLDSSQE 2856 Score = 74.9 bits (176), Expect = 2e-11 Identities = 137/632 (21%), Positives = 277/632 (43%), Gaps = 62/632 (9%) Query: 476 NEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKL 535 N + +L EL ++ + V L +L A+E++ + + NK ++ + + Sbjct: 2324 NTTETFRHKLINELQQKV-ETEVPQLQGQLSEAQEKLKDAQKDAELWNKKYHELLESKQT 2382 Query: 536 KLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIE 595 +++ + + K+S + LT+ S K E +E + +Q D DS + Sbjct: 2383 QVQNILAP-EEIEKLSSEEAKNA-LTQLNKQYSDKAQENKELEMVVQHLRQDLDSSQEKV 2440 Query: 596 SDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQV 655 K+ + +++ E + + LL +Q DLV + + +Q+ ++++KL Q +D Sbjct: 2441 QQQAKEAQQEKSVLEQQTQ---LLNNQLKDLVAKEEVQRQEILDLKNKL---DQENADFW 2494 Query: 656 CSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIM---NKLQN 712 + + + E+Q + S +L + ++ +++ K++ N++ + M K++N Sbjct: 2495 KKQYQQLS-EKQPEISSTQAGDL----QEQQVSQQEREVKPKEILNEERNQMICKKKMKN 2549 Query: 713 YIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELS 772 + K+S ++++L +I + + Q QF D E+ L I ++++E Sbjct: 2550 WKHNRYQFKMNYSKLSNSQMNKLQQQIQKPQGNDQQIQFQTDP---EKVLQISSLQAECV 2606 Query: 773 KYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMD 832 K +I +E+ R+ L+ LG + E Q T + +L + L L + Sbjct: 2607 NLKKQIQDVEQQ------RKDDLKSFEKMLGEGVNETQVI--GLTSDKQQLQSDLRQLQN 2658 Query: 833 HDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESE 892 ++++ +I +N+ LQK QI+ +++ Q S+ ++ K N L E + Sbjct: 2659 KCDQLQQE--QIALQNQLLQKNKQIVDLQDETKQ---SEKEEQIRG---KDNEIKLLEQQ 2710 Query: 893 STKYQTQLRDL-ESNLKRITHEHQT-LIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKY 950 + Q ++L + + +T Q I+Q+ KEI D E +V+NE Sbjct: 2711 VQTAKDQYQELLDLQQQNLTPGGQKEKILQQTKEIHDQE--------------EVINELQ 2756 Query: 951 EKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELID-KHVQKQQTQSPDYTEQYIN 1009 +K V QL+ QL E + +++ + E NK EL++ K Q Q +P+ E+ + Sbjct: 2757 QKVETEVPQLQGQLSEAQEKLKDAQKDAELWNKKYHELLESKQTQVQNILAPEEIEKLSS 2816 Query: 1010 E--INKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRV 1067 E N L L KQ ++ A K V ++ D + Q K E+ + Sbjct: 2817 EEAKNALTQLNKQYSDK--AQENKELEMVVQHLRQDLDSSQEKVQQQAKEAQQEKSVLEQ 2874 Query: 1068 SKQLLDSKQHNEELQILVREQDDQIKELKETK 1099 QLL N +L+ LV +++ Q +E+ + K Sbjct: 2875 QTQLL-----NNQLKDLVAKEEVQRQEILDLK 2901 Score = 74.9 bits (176), Expect = 2e-11 Identities = 116/584 (19%), Positives = 254/584 (43%), Gaps = 51/584 (8%) Query: 1032 INNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSK---QLLDSKQHNEELQILVREQ 1088 IN Q + V + +L++ KL++ +++ + +K +LL+SKQ + IL E+ Sbjct: 2334 INELQQKVETEVPQLQGQLSEAQEKLKDAQKDAELWNKKYHELLESKQTQVQ-NILAPEE 2392 Query: 1089 DDQI--KELKE--TKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKV 1144 +++ +E K T+L + + E + ++ + D ++ KV Sbjct: 2393 IEKLSSEEAKNALTQLNKQYSDKAQENKELEMVVQHLRQDLDSSQE------------KV 2440 Query: 1145 QEE-EEFIQERSVLQEQSAKLNTELQECYTK-IIQLETLNTELTGHDVVNQEQINQLKSK 1202 Q++ +E QE+SVL++Q+ LN +L++ K +Q + + L + ++QE + K + Sbjct: 2441 QQQAKEAQQEKSVLEQQTQLLNNQLKDLVAKEEVQRQEI---LDLKNKLDQENADFWKKQ 2497 Query: 1203 LEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLS 1262 +QL+ + + ST A + +R + E+ + + + +K + Sbjct: 2498 YQQLSEKQPEISSTQAGDLQEQQVSQQEREVKPKEILNEE--RNQMICKKKMKNWKHNRY 2555 Query: 1263 AFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEI 1322 F+ Y +L +S + Q++ K +Q Q +K + +LQ + ++ QI+ Sbjct: 2556 QFKMNYSKLSNSQMNKLQQQIQKPQGNDQQIQFQTD-PEKVLQISSLQAECVNLKKQIQD 2614 Query: 1323 LRSEIEDEKVAF---------XXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNIN-- 1371 + + +D+ +F DLR Q+Q++ I N Sbjct: 2615 VEQQRKDDLKSFEKMLGEGVNETQVIGLTSDKQQLQSDLRQLQNKCDQLQQEQIALQNQL 2674 Query: 1372 -EENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQR 1430 ++N Q+ R D E K+LE Q + + +T + Sbjct: 2675 LQKNKQIVDLQDETKQSEKEEQIRGKDNEIKLLEQQVQTAKDQYQELLDLQQQNLTPGGQ 2734 Query: 1431 NDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEE 1490 ++ +++ + E+ I +L + E+E+ L+ ++ E + QK++E+ K E Sbjct: 2735 KEKILQQTKEIHDQEEVINELQQKVETEVPQLQGQLSEAQEKLKDAQKDAELWNKKYHEL 2794 Query: 1491 LNVKIT--ESVSLNKQVAEL-NKALEEEVAKTNEMQT--ALENQEIEIVTLNDEITNLQN 1545 L K T +++ +++ +L ++ + + + N+ + A EN+E+E+V + +L+ Sbjct: 2795 LESKQTQVQNILAPEEIEKLSSEEAKNALTQLNKQYSDKAQENKELEMV-----VQHLRQ 2849 Query: 1546 MVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAEL 1589 + +S K+Q+ A K ++Q +N +L D V + E+ Sbjct: 2850 DLDSSQEKVQQQAKEAQQEKSVLEQQ-TQLLNNQLKDLVAKEEV 2892 Score = 52.8 bits (121), Expect = 8e-05 Identities = 122/592 (20%), Positives = 255/592 (43%), Gaps = 66/592 (11%) Query: 217 QMTKMQENF--IAMEAE-WKDEKQRLLKDIESKDVRISSLEEANKLL--EA--ARFEISL 269 Q+++ QE +AE W + LL+ +++ I + EE KL EA A +++ Sbjct: 2351 QLSEAQEKLKDAQKDAELWNKKYHELLESKQTQVQNILAPEEIEKLSSEEAKNALTQLNK 2410 Query: 270 EHSKLAQE---LEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTK 326 ++S AQE LE +Q + + +EK+ +E++ L + +L Sbjct: 2411 QYSDKAQENKELEMVVQHLRQDLDSSQEKVQQQAKEAQQEKSVLEQQTQLLNNQLKDLVA 2470 Query: 327 KIELLEH----LNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKM 382 K E+ L ++ Q N + K +E + S ++ G + S + K Sbjct: 2471 KEEVQRQEILDLKNKLDQENADFWKKQYQQLSEKQPEISSTQAGDLQEQQVSQQEREVKP 2530 Query: 383 KSPWSQLSSETLNQDTDK---------KINKNEIAKLEM--VIQSLNKDLVDKEYVISEK 431 K ++ ++ + + K K+N ++++ +M + Q + K + + + + Sbjct: 2531 KEILNEERNQMICKKKMKNWKHNRYQFKMNYSKLSNSQMNKLQQQIQKPQGNDQQIQFQT 2590 Query: 432 DTXXXXXXXXXXGKDT-LIAQLQLEHQQHMEG----PSLIHVGTNTEDVNEIAKVQEQLK 486 D + L Q+Q QQ + ++ G N V + ++QL+ Sbjct: 2591 DPEKVLQISSLQAECVNLKKQIQDVEQQRKDDLKSFEKMLGEGVNETQVIGLTSDKQQLQ 2650 Query: 487 QELN------DEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKN-MIKVKSNH-KLKLK 538 +L D+++ + L +L +QI L DE + K I+ K N KL + Sbjct: 2651 SDLRQLQNKCDQLQQEQIA-LQNQLLQKNKQIVDLQDETKQSEKEEQIRGKDNEIKLLEQ 2709 Query: 539 QMQKTIDNFSKVSD----------SNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDY 588 Q+Q D + ++ D ++I++ T+E+H + + EL+++ L Sbjct: 2710 QVQTAKDQYQELLDLQQQNLTPGGQKEKILQQTKEIHDQEEVINELQQKVETEVPQL--- 2766 Query: 589 DSGRMIESDVYKKMIEMENLAET-RLKAISLLESQKFDLVQEL---HILQQKYDEVEDKL 644 G++ S+ +K+ + + AE K LLES++ + L I + +E ++ L Sbjct: 2767 -QGQL--SEAQEKLKDAQKDAELWNKKYHELLESKQTQVQNILAPEEIEKLSSEEAKNAL 2823 Query: 645 ADISQLQSD--QVCSEIKSV--HLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLE 700 +++ SD Q E++ V HL + +D+ S++++ + + +K L + L Sbjct: 2824 TQLNKQYSDKAQENKELEMVVQHLRQDLDS---SQEKVQQQAKEAQQEKSVLEQQTQLLN 2880 Query: 701 NDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFG 752 N +D++ K + QE +DL +KL++ +A+ + +++ ++ TQ G Sbjct: 2881 NQLKDLVAKEEVQRQEILDLKNKLDQENADFWKKQYQQLSEKQPEISSTQAG 2932 Score = 39.1 bits (87), Expect = 0.99 Identities = 35/149 (23%), Positives = 76/149 (51%), Gaps = 11/149 (7%) Query: 1446 KRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKIT--ESVSLNK 1503 K I +L + E+E+ L+ ++ E + QK++E+ K E L K T +++ + Sbjct: 2332 KLINELQQKVETEVPQLQGQLSEAQEKLKDAQKDAELWNKKYHELLESKQTQVQNILAPE 2391 Query: 1504 QVAEL-NKALEEEVAKTNEMQT--ALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSF 1560 ++ +L ++ + + + N+ + A EN+E+E+V + +L+ + +S K+Q+ Sbjct: 2392 EIEKLSSEEAKNALTQLNKQYSDKAQENKELEMV-----VQHLRQDLDSSQEKVQQQAKE 2446 Query: 1561 ASDTKQGRDEQLDNTMNKELLDAVPRAEL 1589 A K ++Q +N +L D V + E+ Sbjct: 2447 AQQEKSVLEQQ-TQLLNNQLKDLVAKEEV 2474 >UniRef50_A0BYX7 Cluster: Chromosome undetermined scaffold_138, whole genome shotgun sequence; n=2; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_138, whole genome shotgun sequence - Paramecium tetraurelia Length = 929 Score = 126 bits (303), Expect = 7e-27 Identities = 191/889 (21%), Positives = 399/889 (44%), Gaps = 87/889 (9%) Query: 485 LKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTI 544 LK+ +N+ KD + DL +KL+ + ++ + +E++A +N N+ ++ + + I Sbjct: 11 LKKTINE--KDQQIGDLEKKLRLEQFRVKKQQNELNAKIENEKSTAQNNADQINRFELQI 68 Query: 545 DNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIE 604 + K + K I +L+E +K +L EE L+ SG E KK E Sbjct: 69 SDL-KSKVAMKFIFKLSET----EKKNLQLIEEISALKKRRA---SGSTDEDFQPKK--E 118 Query: 605 MENLAETRLKAISLLESQKFDLVQELHILQQKYDEV-EDKLADISQLQSDQVCSEIKSVH 663 + + + + ++++ + + EL + + Y E + K I+ L+ EIK Sbjct: 119 HQGDFPSLQQILGIIQANQGNYQPELTKMYECYTEACQSKDEQINSLKE-----EIKD-- 171 Query: 664 LEEQIDAL-SASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTD 722 L +Q+D S S K+L EQL IK L+ ++ N+L+N +Q+ D +D Sbjct: 172 LTQQLDIKQSDSTKQL-----------EQLEERIKSLKQSLDERENELKNVVQQTSDNSD 220 Query: 723 K----LEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRI 778 + LEK ++SE ++ + F ++ ++ E+ +E+ +++ + + +I Sbjct: 221 QKIQELEKQYQTQLSEKDKQLQETTKKAKFDVFKLNKQLTEQKTVVESEQAKTNLLQQQI 280 Query: 779 CRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVE 838 R E S+ E + LE+K L + KQK + E+ L + D+ Sbjct: 281 DRQESSLREFEIKLSELEQK--NLLLIEEAKQKQQEIERLNEESLTRVQVEEIPQDKPSY 338 Query: 839 KQLLEI--EHENKELQKKNQIL-LEENQNLQISLS-DMQQHYNALVEKANRTDLAESEST 894 ++L+E + + E+ + ++ LEE NL+ + S ++Q+ N +EK D ES Sbjct: 339 EELVEFIQKFQVNEINYQQELKNLEEELNLKNTHSFELQEELNQYIEKVQLQDRKYQESM 398 Query: 895 KYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEF----------NTQIESAIRDKK 944 + L + + + +++ E Q + Q K+E E + EF NT ++ A+ D + Sbjct: 399 RAIKALEEQQISERQVAQELQHYVEQLKQEKEHQQAEFIHKIKELGEHNTNVDDAVNDVE 458 Query: 945 --------VLNEKYEKN----IEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKH 992 + E+Y++ I + Q E +L + + ++ + K + E + Sbjct: 459 QKFQKMMMIQEEQYQRREQELIHQIEQSEEKLSQQEQLLKKQEQKYKNEIKQSEENNSQM 518 Query: 993 VQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALN-QKINNAQVSYMSMVSDYESKLA 1051 +Q++Q Q +Q +E +K+ ++ E+ N +K + + + YE +L+ Sbjct: 519 IQQKQLQVTQLQKQLQDETHKIREDSNKQINELKQENYKKEKSLEQKIQEVTKQYEGELS 578 Query: 1052 QFTTKLENMEEEMQRVSKQLLDSKQHNEE-LQILVREQDDQIKE----LKETKLTFEMNI 1106 + K+E + ++ +R + ++K+ EE LQIL + + I++ +KE ++ ++N Sbjct: 579 KIR-KMEIVLKKKEREIAEEKEAKKFAEEQLQILTEKSNKMIEQYDNKIKEIQIANQVNK 637 Query: 1107 P-KTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLN 1165 + I + S D N L+ + + E E + L E+ L Sbjct: 638 QDQHRNSIFDQRMSISSSDINKT-FEIEVLKAQIEQLQSKGDIELQAEINRLNERERALK 696 Query: 1166 TELQECYTKIIQLETLNTELTGHDVVNQ-----EQINQLK----SKLEQLNTE-NDNLLS 1215 EL + +I E LN + + + ++IN LK S+L+++N E N NL S Sbjct: 697 KELLDLQNEIGN-ERLNFMVVQRQLEKEVESLHQEINNLKQDHQSELDEINKESNKNLSS 755 Query: 1216 TVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSV 1275 + ++ I+ + + ++ K+ E + + +L++++ + E + +L D Sbjct: 756 QKNDFQTKINKLEQKLELQASQFSKKQ-NDIEEEKENIIQQLKIKIKSLEEQIIELKD-- 812 Query: 1276 QSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILR 1324 + + + + ++VT + LQ ++ E R L+++ D+ N+I L+ Sbjct: 813 KKTIKNNSQQVVTQDDTIQLQQEIVSLNEKERVLRKELLDLQNEIGNLK 861 Score = 111 bits (267), Expect = 2e-22 Identities = 169/787 (21%), Positives = 354/787 (44%), Gaps = 86/787 (10%) Query: 534 KLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRM 593 K ++K + + +D K SDS K++ +L E + L Q + E E E N+ D ++ Sbjct: 166 KEEIKDLTQQLD--IKQSDSTKQLEQLEERIKSLKQSLDERENELKNVVQQTSDNSDQKI 223 Query: 594 IESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSD 653 E + K + + L+E + + KFD+ + L ++ VE + A + LQ Sbjct: 224 QELE---KQYQTQ-LSEKDKQLQETTKKAKFDVFKLNKQLTEQKTVVESEQAKTNLLQQ- 278 Query: 654 QVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQ-N 712 Q+ + S+ E +I +K L L+IE K K+Q ++E E+ + ++Q Sbjct: 279 QIDRQESSLR-EFEIKLSELEQKNL-LLIEEAK-QKQQ------EIERLNEESLTRVQVE 329 Query: 713 YIQENM----DLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIE 768 I ++ +L + ++K +I+ N EE+ ++ + + +E + YIE ++ Sbjct: 330 EIPQDKPSYEELVEFIQKFQVNEINYQQELKNLEEELNLKNTHSFELQ-EELNQYIEKVQ 388 Query: 769 SELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLA 828 + KY+ + +I +E+++ S + A +L Y+ E+ K E+ Q+ E ++++ Sbjct: 389 LQDRKYQESM----RAIKALEEQQISERQVAQELQHYV-EQLKQEKEH--QQAEFIHKIK 441 Query: 829 VLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDL 888 L +H+ V+ + ++E ++ QK I E+ Q + L + Q + + + + L Sbjct: 442 ELGEHNTNVDDAVNDVE---QKFQKMMMIQEEQYQRREQEL--IHQIEQSEEKLSQQEQL 496 Query: 889 AESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNE 948 + + KY+ +++ E N ++ + Q + Q +K+++D + I + K N Sbjct: 497 LKKQEQKYKNEIKQSEENNSQMIQQKQLQVTQLQKQLQDETHKIREDSNKQINELKQENY 556 Query: 949 KYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELID----KHVQKQQTQ----- 999 K EK++E +++ ++Y+ + + L K E+ + K ++Q Q Sbjct: 557 KKEKSLE--QKIQEVTKQYEGELSKIRKMEIVLKKKEREIAEEKEAKKFAEEQLQILTEK 614 Query: 1000 SPDYTEQYINEINKL---NALLKQKDEEIIALNQK--INNAQVSYMSMVSDYESKLAQFT 1054 S EQY N+I ++ N + KQ +Q+ I+++ ++ + ++++ Q Sbjct: 615 SNKMIEQYDNKIKEIQIANQVNKQDQHRNSIFDQRMSISSSDINKTFEIEVLKAQIEQLQ 674 Query: 1055 TK--------LENMEEEMQRVSKQLLDSKQH--NEELQILVREQD---------DQIKEL 1095 +K + + E + + K+LLD + NE L +V ++ +I L Sbjct: 675 SKGDIELQAEINRLNERERALKKELLDLQNEIGNERLNFMVVQRQLEKEVESLHQEINNL 734 Query: 1096 KETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERS 1155 K+ + I K +SS N ++ + EEE + + Sbjct: 735 KQDHQSELDEINKESNKNLSSQKNDFQTKINKLEQKLELQASQFSKKQNDIEEE---KEN 791 Query: 1156 VLQEQSAKLNTELQECYTKIIQLETLNT-ELTGHDVVNQEQINQLKSKLEQLNTENDNLL 1214 ++Q+ K+ + L+E +II+L+ T + VV Q+ QL+ ++ LN + L Sbjct: 792 IIQQLKIKIKS-LEE---QIIELKDKKTIKNNSQQVVTQDDTIQLQQEIVSLNEKERVLR 847 Query: 1215 STVAELRSSI-----SSAVDQRGFE-IAELWKQHL--AQREADF-QKTEHELRVQLSAFE 1265 + +L++ I S + R E ++E +KQ AQ+E D+ ++ +L VQ + Sbjct: 848 KELLDLQNEIGNLKLSHTIKIRELETLSEQYKQEANHAQQEQDYAEQMAAKLSVQYAELA 907 Query: 1266 SKYEQLL 1272 +YE ++ Sbjct: 908 MEYENVI 914 Score = 102 bits (244), Expect = 9e-20 Identities = 199/958 (20%), Positives = 404/958 (42%), Gaps = 113/958 (11%) Query: 143 DVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXX 202 D+ L TI EKD + L+ K+++ + + Q ++N K +N+ +T Sbjct: 7 DIQLLKKTINEKDQQIGDLEKKLRLEQFRVKKQQNELNAK-----IENEKSTAQNNADQI 61 Query: 203 XXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIES-KDVRISSLEEANKLLE 261 D K +K+ FI +E + + +L+++I + K R S + + Sbjct: 62 NRFELQIS--DLK---SKVAMKFIFKLSETEKKNLQLIEEISALKKRRASGSTDED---- 112 Query: 262 AARFEISLEHSKLAQELEQXXXXXXXXXXXXX-XLAK--QSIEPSCEEKTEIEEKGSLEI 318 F+ EH L+Q L K + +C+ K E EI Sbjct: 113 ---FQPKKEHQGDFPSLQQILGIIQANQGNYQPELTKMYECYTEACQSKDEQINSLKEEI 169 Query: 319 ANMTEL--------TKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLI 370 ++T+ TK++E LE ++Q+ E EN+L + ++ Sbjct: 170 KDLTQQLDIKQSDSTKQLEQLEERIKSLKQSLDERENELKNVVQQT-------------- 215 Query: 371 SRKSGRNTASKMKSPWSQLSSETLN-QDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVIS 429 S S + K +QLS + Q+T KK AK + + LNK L +++ V+ Sbjct: 216 SDNSDQKIQELEKQYQTQLSEKDKQLQETTKK------AKFD--VFKLNKQLTEQKTVVE 267 Query: 430 EKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQEL 489 + +++ + + +++ + +E +L+ + E AK ++Q + L Sbjct: 268 SEQAKTNLLQQQIDRQESSLREFEIKLSE-LEQKNLLLI--------EEAKQKQQEIERL 318 Query: 490 NDE-IKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFS 548 N+E + V V+++ + S EE L + I N I N++ +LK +++ Sbjct: 319 NEESLTRVQVEEIPQDKPSYEE----LVEFIQKFQVNEI----NYQQELKNLEE------ 364 Query: 549 KVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVD-YDSGRMIESDVYKKMIEMEN 607 +++ N L EEL+ +KV +L++ K + + + ++ E V + E+++ Sbjct: 365 ELNLKNTHSFELQEELNQYIEKV-QLQDRKYQESMRAIKALEEQQISERQVAQ---ELQH 420 Query: 608 LAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQ 667 E +LK E Q+ + + ++ L + V+D + D+ Q + + + EQ Sbjct: 421 YVE-QLKQEK--EHQQAEFIHKIKELGEHNTNVDDAVNDVEQKFQKMMMIQEEQYQRREQ 477 Query: 668 --IDALSASKKELALVIENLKLDKEQLYGTIKDL-ENDKEDIMNKLQNYIQENMDLTDKL 724 I + S+++L+ + LK +++ IK EN+ + I K Q L D+ Sbjct: 478 ELIHQIEQSEEKLSQQEQLLKKQEQKYKNEIKQSEENNSQMIQQKQLQVTQLQKQLQDET 537 Query: 725 EKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEES 784 K+ + + IN +Q + + ++ KIQE + E ELSK + L++ Sbjct: 538 HKIREDSNKQ----INELKQENYKKEKSLEQKIQE---VTKQYEGELSKIRKMEIVLKKK 590 Query: 785 IAVMEDRRYSLERKADQLGSYLQEKQKAYSEY--TIQEDELVNRLAVLMDHDRVVEKQLL 842 + + + + + +QL ++ K +Y I+E ++ N++ H + Q + Sbjct: 591 EREIAEEKEAKKFAEEQLQILTEKSNKMIEQYDNKIKEIQIANQVNKQDQHRNSIFDQRM 650 Query: 843 EIEHENKELQKKNQILLEENQNLQISLS-DMQQHYNAL--VEKANRTDLAE------SES 893 I + + ++L + + LQ ++Q N L E+A + +L + +E Sbjct: 651 SISSSDINKTFEIEVLKAQIEQLQSKGDIELQAEINRLNERERALKKELLDLQNEIGNER 710 Query: 894 TKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKV----LNEK 949 + R LE ++ + E L + E++++ E N + S D + L +K Sbjct: 711 LNFMVVQRQLEKEVESLHQEINNLKQDHQSELDEINKESNKNLSSQKNDFQTKINKLEQK 770 Query: 950 YEKNIEYVTQLEAQLQEYKNN-IENLNMNVEELNKMNLELIDKHVQK---QQTQSPDYTE 1005 E ++ + ++E K N I+ L + ++ L + +EL DK K QQ + D T Sbjct: 771 LELQASQFSKKQNDIEEEKENIIQQLKIKIKSLEEQIIELKDKKTIKNNSQQVVTQDDTI 830 Query: 1006 QYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEE 1063 Q EI LN + +E++ L +I N ++S+ + + E+ Q+ + + ++E Sbjct: 831 QLQQEIVSLNEKERVLRKELLDLQNEIGNLKLSHTIKIRELETLSEQYKQEANHAQQE 888 Score = 75.4 bits (177), Expect = 1e-11 Identities = 133/724 (18%), Positives = 309/724 (42%), Gaps = 43/724 (5%) Query: 907 LKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKY--EKNIEYVTQLEAQL 964 LK+ +E I +K++ LE +F + + + K+ NEK + N + + + E Q+ Sbjct: 11 LKKTINEKDQQIGDLEKKLR-LE-QFRVKKQQNELNAKIENEKSTAQNNADQINRFELQI 68 Query: 965 QEYKNNIE-NLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDE 1023 + K+ + + E K NL+LI++ ++ ++ T++ + + Sbjct: 69 SDLKSKVAMKFIFKLSETEKKNLQLIEEISALKKRRASGSTDEDFQPKKEHQGDFPSLQQ 128 Query: 1024 EIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQI 1083 + + N Q M Y ++ +++EE++ +++QL D KQ + Q+ Sbjct: 129 ILGIIQANQGNYQPELTKMYECYTEACQSKDEQINSLKEEIKDLTQQL-DIKQSDSTKQL 187 Query: 1084 LVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSD-------DANNVDXXXXXXX 1136 + +++IK LK++ E + ++ + + + + D Sbjct: 188 --EQLEERIKSLKQSLDERENELKNVVQQTSDNSDQKIQELEKQYQTQLSEKDKQLQETT 245 Query: 1137 XXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQEC---YTKIIQLETLNTELTGHDVVNQ 1193 + ++ ++++V++ + AK N Q+ + + + E +EL +++ Sbjct: 246 KKAKFDVFKLNKQLTEQKTVVESEQAKTNLLQQQIDRQESSLREFEIKLSELEQKNLLLI 305 Query: 1194 EQINQLKSKLEQLNTENDNLLST--VAELRSSISSAVDQ-RGFEIAEL-WKQHLAQREAD 1249 E+ Q + ++E+LN E+ + + + + S V+ + F++ E+ ++Q L E + Sbjct: 306 EEAKQKQQEIERLNEESLTRVQVEEIPQDKPSYEELVEFIQKFQVNEINYQQELKNLEEE 365 Query: 1250 FQ-KTEH--ELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQ--NKLQDKEE 1304 K H EL+ +L+ + K QL D + K + +Q++ Q +LQ E Sbjct: 366 LNLKNTHSFELQEELNQYIEKV-QLQDRKYQESMRAI-KALEEQQISERQVAQELQHYVE 423 Query: 1305 HLRNLQE-KYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQ 1363 L+ +E + A+ I++I+ L + A + Q Sbjct: 424 QLKQEKEHQQAEFIHKIKELGEHNTNVDDAVNDVEQKFQKMMMIQEEQYQRREQELIHQI 483 Query: 1364 EQSILNINEENAQLKKSSXXXXXXXXXXXXR----VNDAEAKVLELTHQLELKDSEIYQK 1419 EQS ++++ LKK + + +V +L QL+ + +I + Sbjct: 484 EQSEEKLSQQEQLLKKQEQKYKNEIKQSEENNSQMIQQKQLQVTQLQKQLQDETHKIRED 543 Query: 1420 THEYTITLTQRNDEFE-NVRQQLVEYEKRIE-DLTYEKESELAILRLKMHENANHYETMQ 1477 +++ L Q N + E ++ Q++ E K+ E +L+ ++ E+ +L+ K E A E Sbjct: 544 SNKQINELKQENYKKEKSLEQKIQEVTKQYEGELSKIRKMEI-VLKKKEREIAEEKEA-- 600 Query: 1478 KESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLN 1537 K+ E+++++ E + K+ E + ++ E+ + +V K ++ + ++ +Q + I + + Sbjct: 601 KKFAEEQLQILTEKSNKMIE--QYDNKIKEIQ--IANQVNKQDQHRNSIFDQRMSISSSD 656 Query: 1538 DEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDLAMYMLH 1597 T +++A ++Q + R + + + KELLD + +M+ Sbjct: 657 INKTFEIEVLKAQIEQLQSKGDIELQAEINRLNERERALKKELLDLQNEIGNERLNFMVV 716 Query: 1598 QRDV 1601 QR + Sbjct: 717 QRQL 720 Score = 48.0 bits (109), Expect = 0.002 Identities = 101/536 (18%), Positives = 223/536 (41%), Gaps = 57/536 (10%) Query: 220 KMQENFIAMEAEWKDEKQRLLKDIESKDV--RISSLEEANKLLEAARFEISLEHSKLAQE 277 ++ E +A E + E+ + K+ + + +I L E N ++ A ++ + K+ Sbjct: 408 QISERQVAQELQHYVEQLKQEKEHQQAEFIHKIKELGEHNTNVDDAVNDVEQKFQKMMMI 467 Query: 278 LEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQ 337 E+ +++ + + + E+K EI E ++++ Q Sbjct: 468 QEEQYQRREQELIHQIEQSEEKLSQQEQLLKKQEQKYKNEIKQSEE--NNSQMIQQKQLQ 525 Query: 338 IRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQD 397 + Q K+L+++ + +S + K+ + K ++ K++ Q E Sbjct: 526 VTQLQKQLQDETHKIREDSNKQINELKQEN----YKKEKSLEQKIQEVTKQYEGEL---- 577 Query: 398 TDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQ 457 KI K EI L+ + + ++ K++ + D I ++Q+ +Q Sbjct: 578 --SKIRKMEIV-LKKKEREIAEEKEAKKFAEEQLQILTEKSNKMIEQYDNKIKEIQIANQ 634 Query: 458 -----QHMEGPSLIHVGTNTEDVN-----EIAKVQEQLKQELNDEIKDVNVKDLIEKLKS 507 QH + ++ D+N E+ K Q + Q D + L E+ ++ Sbjct: 635 VNKQDQHRNSIFDQRMSISSSDINKTFEIEVLKAQIEQLQSKGDIELQAEINRLNERERA 694 Query: 508 AEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHL 567 ++++ L +EI N + V+ + +++ + + I+N + D E+ +E++ Sbjct: 695 LKKELLDLQNEIGNERLNFMVVQRQLEKEVESLHQEINNLKQ--DHQSEL----DEINKE 748 Query: 568 SQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLV 627 S K L +K + Q + + K ++E A K + +E +K +++ Sbjct: 749 SNK--NLSSQKNDFQ-------------TKINKLEQKLELQASQFSKKQNDIEEEKENII 793 Query: 628 QELHILQQKYDEVEDKLADISQLQ--SDQVCSEIKSVHLEEQIDALSASKKELALVIENL 685 Q+L I + +E +L D ++ S QV ++ ++ L+++I +S ++KE L E L Sbjct: 794 QQLKIKIKSLEEQIIELKDKKTIKNNSQQVVTQDDTIQLQQEI--VSLNEKERVLRKELL 851 Query: 686 KLDKE----QLYGTIK--DLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISEL 735 L E +L TIK +LE E + N+ Q+ D +++ + + +EL Sbjct: 852 DLQNEIGNLKLSHTIKIRELETLSEQYKQE-ANHAQQEQDYAEQMAAKLSVQYAEL 906 >UniRef50_UPI00015B5164 Cluster: PREDICTED: similar to ENSANGP00000005723; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to ENSANGP00000005723 - Nasonia vitripennis Length = 1515 Score = 125 bits (302), Expect = 9e-27 Identities = 250/1229 (20%), Positives = 539/1229 (43%), Gaps = 122/1229 (9%) Query: 147 LSNTIKEKDNALSVLQVKMKI----------METTILDLQEKINEK-DQIIEAKNKATTX 195 L N I+EKD+ ++ L+ K+K+ +ET + K +K D +++ N + Sbjct: 210 LRNDIEEKDHVINSLRTKIKLIQEKSPNIEGLETVEISENHKEGDKVDILVDLSNNSEPD 269 Query: 196 XXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEE 255 + + ++ ++ ++ K++ + + ++E+ +L E Sbjct: 270 QPKKYKDMLKRSKDKMLEMTNEKNTLERDYDILQKSSKEKLESVESELENSKEGFKNLRE 329 Query: 256 ANKLLEAARFE--ISLEHSKLA--QELE------QXXXXXXXXXXXXXXLAKQSIE-PSC 304 +L+ E ISL +KL+ +ELE + K+SIE Sbjct: 330 ELDVLKKREEESVISLAENKLSIHRELEGKEEQIKQLRSELKQTLEHEKALKESIETQKL 389 Query: 305 E-EKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPS 363 E EK ++ + E AN L K E L+ + +++Q +LE TMG + + Sbjct: 390 ELEKVKLVANQNAE-ANQEHLRGKSEALKKVQSEMQQKLIDLEE---TMGAK---YHEEA 442 Query: 364 KKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINK-NEIAKLEMVIQSLNKDLV 422 K L+S+ SK +Q SE L + T K +K N++++L ++ K+ Sbjct: 443 NKNKELLSKIEELEKQSKE----TQHGSEALEKLTKKLQDKENQVSEL-----AIKKE-- 491 Query: 423 DKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQ 482 + E ++ E T + ++Q E E S +++NE+ K Sbjct: 492 EYEKLLEEYKTQNTNLNKEFTEIRNSLEKIQTE----TETSSNALKDKYEKEINELKKTL 547 Query: 483 EQLKQELNDEIKDVNVKDLIEKLK-SAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQ 541 E+ K +++++ ++ +++ E K S EE++ +L DE ++ N ++ + S +LK + Sbjct: 548 EE-KTDISEK-SNLKIQEYTEASKTSDEEKMLRLQDEFESKNTEILGLNS----ELKSYR 601 Query: 542 KTIDNFSK-VSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVD-YDSGRMIESDVY 599 TI + K ++ L + L + V L+++ +L+ + G+ SD Sbjct: 602 TTITDLKKEINILANHRQNLVKNLKSCKKAVKGLKQDCASLKNDVHSRISEGKCAISDAV 661 Query: 600 KKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEI 659 +K + + + + + I+ L+SQ +L ++ L++ D S +Q +++ SE Sbjct: 662 EKTVNVFPMMDEK---INNLQSQIVELTEKTKTLEEFNRNCSD-----SNVQLEKILSE- 712 Query: 660 KSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMD 719 + LE+++ A K+ I+ +D +L L++D E++ K+ Y + + Sbjct: 713 -KMALEKELQA----KQHEVETIQAKLIDFGELKENNGKLQSDIENLNFKISEYEKLCTE 767 Query: 720 LTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRIC 779 + ++++ EK LL I ++Q K+ ++++ + E +K I Sbjct: 768 HSMEIQEAKLEK-DNLLKDITLKKQHNESLIQEFSQKLSDKEVITQEFHEERNKLIHEIQ 826 Query: 780 RLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEK 839 LE +A +++ L +K +L YLQ K E T + L++ + Sbjct: 827 VLEFELASIKE---ELGKKNTEL-QYLQTKTTEEGEQTDKITNECENYKKLLEENNQTLS 882 Query: 840 QLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHY------NALVEKANRTDLAESES 893 QL E +K+ + K +I L+E+++ D + + + L D ++E Sbjct: 883 QLNEELKNSKDERDKIRIELQESKDSLQKAMDTKNGFLQKLKLDELKSSKGELDSLKNEK 942 Query: 894 TKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFN---TQIESAIRDKKVLNEKY 950 +L++++S L + H + + ++ L N +++ +R+ + N+ Sbjct: 943 VIMAEELKEIKS-LHDLLHNENKSLKDNQNDLLRLNEVLNQSQSELTEKLRNLEKKNDDI 1001 Query: 951 EK-NIEYVTQLEA---QLQEYKNNIENLN---MNVEELNKMNLE---LIDKHVQKQQTQS 1000 K N ++T++E QL+ + IENL +E++ K N E L+++ QQ + Sbjct: 1002 AKENNAFLTEIETFKYQLKNAHSEIENLKSQLAELEDMRKKNNELSILLNEANNHQQNSA 1061 Query: 1001 PDYTE-QYINEINK-LNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLE 1058 +TE + + + N+ LN+ L+ + +I+AL +K + A V+ + ++ + L Sbjct: 1062 QLFTEVERLTDTNRSLNSELQNLNNKILAL-EKQHEASVNLEHELQVCRDRIVELENNLS 1120 Query: 1059 NMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTI 1118 + +E+ S +++ HN +++ + ELK TKL E++ + SS + Sbjct: 1121 SKIQELNSFSSN-SENECHNLRIELEEKNGVLNEMELKNTKLLEEID------QLSSSKL 1173 Query: 1119 EPMSDDANNVDXXXXXXXXXXXXLKVQEEE--EFIQER-SVLQEQSAKLNTELQECYTKI 1175 + ++ L +EE + IQ+ S ++ ++L+ L K Sbjct: 1174 DSEEKANQEINKLREASIEFEKNLSDKEENLTKNIQDAISEKRKIESQLDETLVTFQAKE 1233 Query: 1176 IQLETLNTELTGHDVVNQEQ--INQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGF 1233 Q++ LN EL +EQ IN+ + L +L + + + + +A+++R F Sbjct: 1234 TQMQVLNEELRNQAAKLREQLKINEEEQSL-RLKQIVKEFQAQLHDKEKELQAALEKR-F 1291 Query: 1234 EIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLL---DSVQSSTQEETNKIVTME 1290 + + ++ + Q ++++ + +V+L+ + E+L+ ++ + QEE K+ ++ Sbjct: 1292 DRQQNYESDIIQ---EYREQLKDFQVELTKKSEEIERLILNNENTKKEAQEEFEKL--LD 1346 Query: 1291 QVTSLQNKLQDKEEHLRNLQEKYADVINQ 1319 + Q KL+ KEE ++ L+ ++ ++NQ Sbjct: 1347 NIN--QIKLEHKEE-IQELERRWKHIVNQ 1372 Score = 112 bits (270), Expect = 7e-23 Identities = 206/1112 (18%), Positives = 466/1112 (41%), Gaps = 79/1112 (7%) Query: 500 DLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVR 559 DL+ + E T+L + ++ S+ K + + Q+ + + +I Sbjct: 159 DLVTHYREIERAKTKLESLLVETQDKALRRISDLKEQCQLEQQAKAHLEEAL--RNDIEE 216 Query: 560 LTEELHHLSQKVAELEEEKGNLQ-LHLVDYDSGRMIESDVYKKMIEMENLAETRL--KAI 616 ++ L K+ ++E+ N++ L V+ E D ++++ N +E K Sbjct: 217 KDHVINSLRTKIKLIQEKSPNIEGLETVEISENHK-EGDKVDILVDLSNNSEPDQPKKYK 275 Query: 617 SLLESQK---FDLVQELHILQQKYDEVEDKLAD-ISQLQSDQVCSEIKSVHLEEQIDALS 672 +L+ K ++ E + L++ YD ++ + + ++S+ S+ +L E++D L Sbjct: 276 DMLKRSKDKMLEMTNEKNTLERDYDILQKSSKEKLESVESELENSKEGFKNLREELDVLK 335 Query: 673 ASKKELALVIENLKLD-KEQLYGTIKDLENDKEDIMNKLQNY--IQENMDLTDKLEKMSA 729 ++E + + KL +L G + ++ + ++ L++ ++E+++ T KLE Sbjct: 336 KREEESVISLAENKLSIHRELEGKEEQIKQLRSELKQTLEHEKALKESIE-TQKLELEKV 394 Query: 730 EKISELLAKINHEE-QSKIQTQFGIDAKIQERDLYIENI-----ESELSKYKSRICRLEE 783 + ++ A+ N E + K + + +++Q++ + +E E +K K + ++EE Sbjct: 395 KLVANQNAEANQEHLRGKSEALKKVQSEMQQKLIDLEETMGAKYHEEANKNKELLSKIEE 454 Query: 784 SIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLE 843 ++ ++ E ++L LQ+K+ SE I+++E L + + K+ E Sbjct: 455 LEKQSKETQHGSEA-LEKLTKKLQDKENQVSELAIKKEEYEKLLEEYKTQNTNLNKEFTE 513 Query: 844 IEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDL 903 I + +++Q + + N ++ + L EK TD++E + K Q Sbjct: 514 IRNSLEKIQTETET--SSNALKDKYEKEINELKKTLEEK---TDISEKSNLKIQEYTEAS 568 Query: 904 ESNLKRITHEHQTLIVQKKKEIEDLEIE---FNTQIESAIRDKKVLNEKYEKNIEYVTQL 960 +++ + Q K EI L E + T I ++ +L + ++ + Sbjct: 569 KTSDEEKMLRLQDEFESKNTEILGLNSELKSYRTTITDLKKEINILANHRQNLVKNLKSC 628 Query: 961 EAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQ 1020 + ++ K + +L +V I V+K P E+ IN + L + Sbjct: 629 KKAVKGLKQDCASLKNDVHSRISEGKCAISDAVEKTVNVFPMMDEK-INNLQSQIVELTE 687 Query: 1021 KDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDS---KQH 1077 K + + N+ +++ V ++S+ K+A +L+ + E++ + +L+D K++ Sbjct: 688 KTKTLEEFNRNCSDSNVQLEKILSE---KMA-LEKELQAKQHEVETIQAKLIDFGELKEN 743 Query: 1078 NEELQILVREQDDQIKELKE--TKLTFEMNIPKTE--GMIISSTIEPMSDDANNVDXXXX 1133 N +LQ + + +I E ++ T+ + E+ K E ++ T++ +++ + Sbjct: 744 NGKLQSDIENLNFKISEYEKLCTEHSMEIQEAKLEKDNLLKDITLKKQHNESLIQEFSQK 803 Query: 1134 XXXXXXXXLKVQEEE-EFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVN 1192 + EE + I E VL+ + A + EL + T++ L+T TE Sbjct: 804 LSDKEVITQEFHEERNKLIHEIQVLEFELASIKEELGKKNTELQYLQTKTTE-------E 856 Query: 1193 QEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQK 1252 EQ +++ ++ E + T+++L + ++ D+R EL + + ++A K Sbjct: 857 GEQTDKITNECENYKKLLEENNQTLSQLNEELKNSKDERDKIRIELQESKDSLQKAMDTK 916 Query: 1253 TEHELRVQLSAFESKYEQLLDSVQSST---QEETNKIVTMEQVTSLQNK-LQDKEEHLRN 1308 +++L +S +L DS+++ EE +I ++ + +NK L+D + L Sbjct: 917 NGFLQKLKLDELKSSKGEL-DSLKNEKVIMAEELKEIKSLHDLLHNENKSLKDNQNDLLR 975 Query: 1309 LQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSIL 1368 L E V+NQ + SE+ ++ D+ EN ++ + E Sbjct: 976 LNE----VLNQSQ---SELTEK-----------LRNLEKKNDDIAKENNAF--LTEIETF 1015 Query: 1369 NINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLT 1428 +NA + + + N+ + +L + + ++++ + T T Sbjct: 1016 KYQLKNAHSEIENLKSQLAELEDMRKKNNELSILLNEANNHQQNSAQLFTEVERLTDTNR 1075 Query: 1429 QRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLI 1488 N E +N+ +++ EK+ E + E EL + R ++ E N+ + +E Sbjct: 1076 SLNSELQNLNNKILALEKQHE-ASVNLEHELQVCRDRIVELENNLSSKIQELNSFSSNSE 1134 Query: 1489 EE---LNVKITESVS-LNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQ 1544 E L +++ E LN+ + K LEE ++ + E EI L + + Sbjct: 1135 NECHNLRIELEEKNGVLNEMELKNTKLLEEIDQLSSSKLDSEEKANQEINKLREASIEFE 1194 Query: 1545 NMVRASSSKIQKHVSFASDTKQGRDEQLDNTM 1576 + + K++ A K+ + QLD T+ Sbjct: 1195 KNLSDKEENLTKNIQDAISEKRKIESQLDETL 1226 Score = 105 bits (251), Expect = 1e-20 Identities = 205/1054 (19%), Positives = 440/1054 (41%), Gaps = 82/1054 (7%) Query: 573 ELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHI 632 E+E K L+ LV+ + K+ ++E A+ L+ + ++ D V ++ Sbjct: 166 EIERAKTKLESLLVETQDKALRRISDLKEQCQLEQQAKAHLEEALRNDIEEKDHV--INS 223 Query: 633 LQQKYDEVEDKLADISQLQSDQVCSEIKSVH-LEEQIDALSASKKELALVIEN-LKLDKE 690 L+ K +++K +I L++ ++ K ++ +D + S+ + ++ LK K+ Sbjct: 224 LRTKIKLIQEKSPNIEGLETVEISENHKEGDKVDILVDLSNNSEPDQPKKYKDMLKRSKD 283 Query: 691 QLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKIN----HEEQSK 746 ++ + +N E + LQ +E ++ + + S E L +++ EE+S Sbjct: 284 KMLEMTNE-KNTLERDYDILQKSSKEKLESVESELENSKEGFKNLREELDVLKKREEESV 342 Query: 747 I---QTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLG 803 I + + I +++ ++ I+ + SEL + L+ESI + ++ A+Q Sbjct: 343 ISLAENKLSIHRELEGKEEQIKQLRSELKQTLEHEKALKESIETQKLELEKVKLVANQNA 402 Query: 804 SYLQEKQKAYSEYTIQ-EDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEEN 862 QE + SE + + E+ +L +D + + + E ++NKEL K + L +++ Sbjct: 403 EANQEHLRGKSEALKKVQSEMQQKL---IDLEETMGAKYHEEANKNKELLSKIEELEKQS 459 Query: 863 QNLQISLSDMQQHYNALVEKANR-TDLA--ESESTKYQTQLRDLESNLKRITHEHQTLIV 919 + Q +++ L +K N+ ++LA + E K + + +NL + E + + Sbjct: 460 KETQHGSEALEKLTKKLQDKENQVSELAIKKEEYEKLLEEYKTQNTNLNKEFTEIRNSLE 519 Query: 920 QKKKEIEDLEIEFNTQIESAIRD-KKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNV 978 + + E E + E I + KK L EK + + + +++ + K + E + + Sbjct: 520 KIQTETETSSNALKDKYEKEINELKKTLEEKTDISEKSNLKIQEYTEASKTSDEEKMLRL 579 Query: 979 -EELNKMNLEL--IDKHVQKQQTQSPDYTEQ---YINEINKLNALLKQKDEEIIALNQKI 1032 +E N E+ ++ ++ +T D ++ N L LK + + L Q Sbjct: 580 QDEFESKNTEILGLNSELKSYRTTITDLKKEINILANHRQNLVKNLKSCKKAVKGLKQDC 639 Query: 1033 NNAQVSYMSMVSDYESKLAQFTTKLEN----MEEEMQRVSKQLLDSKQHNEELQILVREQ 1088 + + S +S+ + ++ K N M+E++ + Q+++ + + L+ R Sbjct: 640 ASLKNDVHSRISEGKCAISDAVEKTVNVFPMMDEKINNLQSQIVELTEKTKTLEEFNRNC 699 Query: 1089 DD---QIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXL--K 1143 D Q++++ K+ E + + + TI+ D + L K Sbjct: 700 SDSNVQLEKILSEKMALEKELQAKQHEV--ETIQAKLIDFGELKENNGKLQSDIENLNFK 757 Query: 1144 VQEEEEFIQERSV-LQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSK 1202 + E E+ E S+ +QE + + L++ K E+L E + + ++E I Q Sbjct: 758 ISEYEKLCTEHSMEIQEAKLEKDNLLKDITLKKQHNESLIQEFS-QKLSDKEVITQ---- 812 Query: 1203 LEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAEL-WKQHLAQREAD-FQKTEHELRVQ 1260 + + E + L+ + L ++S ++ G + EL + Q E + K +E Sbjct: 813 --EFHEERNKLIHEIQVLEFELASIKEELGKKNTELQYLQTKTTEEGEQTDKITNECENY 870 Query: 1261 LSAFESKYE---QLLDSVQSSTQEETN-KIVTMEQVTSLQNKLQDKE--------EHLRN 1308 E + QL + +++S E +I E SLQ + K + L++ Sbjct: 871 KKLLEENNQTLSQLNEELKNSKDERDKIRIELQESKDSLQKAMDTKNGFLQKLKLDELKS 930 Query: 1309 LQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTE---NQSYKQMQEQ 1365 + + + N+ I+ E+++ K LR NQS ++ E+ Sbjct: 931 SKGELDSLKNEKVIMAEELKEIKSLHDLLHNENKSLKDNQNDLLRLNEVLNQSQSELTEK 990 Query: 1366 SILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQL-ELKDSEIYQKTHEYT 1424 + N+ ++N + K + ++ +A +++ L QL EL+D + +K +E + Sbjct: 991 -LRNLEKKNDDIAKENNAFLTEIETFKYQLKNAHSEIENLKSQLAELED--MRKKNNELS 1047 Query: 1425 ITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIER 1484 I L + N+ +N Q E E R+ D SEL L N ++K+ E Sbjct: 1048 ILLNEANNHQQNSAQLFTEVE-RLTDTNRSLNSELQNLN-------NKILALEKQHEAS- 1098 Query: 1485 VKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQ 1544 V L EL V ++ EL L ++ + N + EN+ + +E + Sbjct: 1099 VNLEHELQV-------CRDRIVELENNLSSKIQELNSFSSNSENECHNLRIELEEKNGVL 1151 Query: 1545 NMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNK 1578 N + ++K+ + + S +K +E+ + +NK Sbjct: 1152 NEMELKNTKLLEEIDQLSSSKLDSEEKANQEINK 1185 Score = 85.4 bits (202), Expect = 1e-14 Identities = 212/1069 (19%), Positives = 430/1069 (40%), Gaps = 111/1069 (10%) Query: 50 RQIKFERAQKCLENAALVSKRIKEHRKATAELLGRPFVPGISESLANTLKQKEILMEKIK 109 ++++ E QK ++ + + E ELL + + + + T E L + K Sbjct: 417 KKVQSEMQQKLIDLEETMGAKYHEEANKNKELLSK--IEELEKQSKETQHGSEALEKLTK 474 Query: 110 QYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNALSVLQVKMKIME 169 + ++ + S ++ T+L+ E N+L +Q + + Sbjct: 475 KLQDKENQVSELAIKKEEYEKLLEEYKTQN-----TNLNKEFTEIRNSLEKIQTETETSS 529 Query: 170 TTILDLQEK-INEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAM 228 + D EK INE + +E K + E+ +M ++Q+ F + Sbjct: 530 NALKDKYEKEINELKKTLEEKTDISEKSNLKIQEYTEASKTSDEE---KMLRLQDEFESK 586 Query: 229 EAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEI--SLEHSKLAQE-LEQXXXXX 285 E L +++S I+ L++ +L R + +L+ K A + L+Q Sbjct: 587 NTEILG----LNSELKSYRTTITDLKKEINILANHRQNLVKNLKSCKKAVKGLKQDCASL 642 Query: 286 XXXXXXXXXLAKQSIEPSCEEKTEI----EEKGSLEIANMTELTKKIELLEHLNCQIRQT 341 K +I + E+ + +EK + + + ELT+K + LE N + Sbjct: 643 KNDVHSRISEGKCAISDAVEKTVNVFPMMDEKINNLQSQIVELTEKTKTLEEFNRNCSDS 702 Query: 342 N--------------KELENKLATMGT-ESKAVSSPSKKGSPLISRKSGRNTASKMKSPW 386 N KEL+ K + T ++K + K + + N K+ S + Sbjct: 703 NVQLEKILSEKMALEKELQAKQHEVETIQAKLIDFGELKENNGKLQSDIENLNFKI-SEY 761 Query: 387 SQLSSETLNQDTDKKINKNEIAK--------LEMVIQSLNKDLVDKEYVISE-------- 430 +L +E + + K+ K+ + K E +IQ ++ L DKE + E Sbjct: 762 EKLCTEHSMEIQEAKLEKDNLLKDITLKKQHNESLIQEFSQKLSDKEVITQEFHEERNKL 821 Query: 431 ------KDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQ 484 + K+T + LQ + + EG + E+ ++ + Q Sbjct: 822 IHEIQVLEFELASIKEELGKKNTELQYLQTKTTE--EGEQTDKITNECENYKKLLEENNQ 879 Query: 485 LKQELNDEIKDVNVKDLIEKLK-SAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKT 543 +LN+E+K N KD +K++ +E L +D N + K+K + K + Sbjct: 880 TLSQLNEELK--NSKDERDKIRIELQESKDSLQKAMDTKNGFLQKLKLDELKSSKGELDS 937 Query: 544 IDNFSKV-SDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKM 602 + N + ++ KEI L + LH+ ++ + + + + L+L+ V S + + Sbjct: 938 LKNEKVIMAEELKEIKSLHDLLHNENKSLKDNQNDL--LRLNEVLNQSQSELTEKLRNLE 995 Query: 603 IEMENLAETRLKAISLLESQKFDLVQ---ELHILQQKYDEVED---KLADISQLQSDQVC 656 + +++A+ ++ +E+ K+ L E+ L+ + E+ED K ++S L ++ Sbjct: 996 KKNDDIAKENNAFLTEIETFKYQLKNAHSEIENLKSQLAELEDMRKKNNELSILLNEANN 1055 Query: 657 SEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQE 716 + S L +++ L+ + + L ++NL I LE E +N L++ +Q Sbjct: 1056 HQQNSAQLFTEVERLTDTNRSLNSELQNLN-------NKILALEKQHEASVN-LEHELQV 1107 Query: 717 NMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAK---IQERDLYIENIESELSK 773 D +LE + KI EL + ++ E + ++ K + E +L + E+ + Sbjct: 1108 CRDRIVELENNLSSKIQELNSFSSNSENECHNLRIELEEKNGVLNEMELKNTKLLEEIDQ 1167 Query: 774 YKSRICRLEESI--AVMEDRRYSLERK---ADQLGSYLQEKQKAYSEYTIQEDELVNRLA 828 S EE + + R S+E + +D+ + + Q A SE E +L L Sbjct: 1168 LSSSKLDSEEKANQEINKLREASIEFEKNLSDKEENLTKNIQDAISEKRKIESQLDETLV 1227 Query: 829 VLMDHDRVVEKQLLEIEHENKELQKKNQILL-EENQNL---------QISLSDMQQHYNA 878 + + Q+L E N+ + + Q+ + EE Q+L Q L D ++ A Sbjct: 1228 TFQAKE--TQMQVLNEELRNQAAKLREQLKINEEEQSLRLKQIVKEFQAQLHDKEKELQA 1285 Query: 879 LVEKA-NRTDLAESESTK-YQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQI 936 +EK +R ES+ + Y+ QL+D + L + + E + LI+ + ++ + EF + Sbjct: 1286 ALEKRFDRQQNYESDIIQEYREQLKDFQVELTKKSEEIERLILNNENTKKEAQEEFEKLL 1345 Query: 937 ESA----IRDKKVLNEKYEKNIEYVTQLEAQLQ-EYKNNIENLN--MNVEELNKMNLELI 989 ++ + K+ + E + V Q +QL+ ++++ I L E N N EL+ Sbjct: 1346 DNINQIKLEHKEEIQELERRWKHIVNQKTSQLETKHEHEIAELTNEWKNERKNDENTELL 1405 Query: 990 DKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVS 1038 DK ++ + + + L L + E+ L + + Q S Sbjct: 1406 DKELESTTRVAMAAVQSNTGSFHTLQQTLLSQKRELAELRKLVKLRQES 1454 Score = 78.6 bits (185), Expect = 1e-12 Identities = 129/719 (17%), Positives = 300/719 (41%), Gaps = 60/719 (8%) Query: 859 LEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLE---SNLKRITHEHQ 915 +++N + Q+ +Q Y+A + + D + T R++E + L+ + E Q Sbjct: 123 IDDNISPQLDRVSKEQLYSAYRKARTKYDKYRGRFSDLVTHYREIERAKTKLESLLVETQ 182 Query: 916 TLIVQKKKEIED---LEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIE 972 +++ ++++ LE + +E A+R+ + EK T+++ +QE NIE Sbjct: 183 DKALRRISDLKEQCQLEQQAKAHLEEALRND--IEEKDHVINSLRTKIKL-IQEKSPNIE 239 Query: 973 NLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKI 1032 L N + +D V PD ++Y +LK+ ++++ + + Sbjct: 240 GLETVEISENHKEGDKVDILVDLSNNSEPDQPKKY-------KDMLKRSKDKMLEMTNEK 292 Query: 1033 NNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQI 1092 N + Y + + KL ++LEN +E K EEL +L + +++ + Sbjct: 293 NTLERDYDILQKSSKEKLESVESELENSKEGF----------KNLREELDVLKKREEESV 342 Query: 1093 KELKETKLTFEMNIPKTEGMI--ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEF 1150 L E KL+ + E I + S ++ + + +K+ + Sbjct: 343 ISLAENKLSIHRELEGKEEQIKQLRSELKQTLEHEKALKESIETQKLELEKVKLVANQNA 402 Query: 1151 IQERSVLQEQSAKLNTELQECYTKIIQL-ETLNTELTGHDVVNQEQINQLKSKLEQLNTE 1209 + L+ +S L E K+I L ET+ + H+ N+ + +L SK+E+L + Sbjct: 403 EANQEHLRGKSEALKKVQSEMQQKLIDLEETMGAKY--HEEANKNK--ELLSKIEELEKQ 458 Query: 1210 NDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYE 1269 + +E ++ + + +++E LA ++ +++K E + Q + ++ Sbjct: 459 SKE-TQHGSEALEKLTKKLQDKENQVSE-----LAIKKEEYEKLLEEYKTQNTNLNKEFT 512 Query: 1270 QLLDSVQS-STQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQ-IEILRSEI 1327 ++ +S++ T+ ET+ ++ N+L+ E ++ EK I + E ++ Sbjct: 513 EIRNSLEKIQTETETSSNALKDKYEKEINELKKTLEEKTDISEKSNLKIQEYTEASKTSD 572 Query: 1328 EDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQ-SILNINEEN--AQLKKSSXXX 1384 E++ + +L++ + ++++ +IL + +N LK Sbjct: 573 EEKMLRLQDEFESKNTEILGLNSELKSYRTTITDLKKEINILANHRQNLVKNLKSCKKAV 632 Query: 1385 XXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEY 1444 ND +++ E + S+ +KT + ++ + ++ +L E Sbjct: 633 KGLKQDCASLKNDVHSRISEGKCAI----SDAVEKTVNVFPMMDEKINNLQSQIVELTEK 688 Query: 1445 EKRIEDLTYE-KESELAILRLKMHENANHYETMQKESEIERV--KLIE-----ELNVKIT 1496 K +E+ +S + + ++ + A E K+ E+E + KLI+ E N K+ Sbjct: 689 TKTLEEFNRNCSDSNVQLEKILSEKMALEKELQAKQHEVETIQAKLIDFGELKENNGKLQ 748 Query: 1497 ESV-SLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKI 1554 + +LN +++E K E + E + +N ++ +TL + + +++++ S K+ Sbjct: 749 SDIENLNFKISEYEKLCTEHSMEIQEAKLEKDNL-LKDITLKKQ--HNESLIQEFSQKL 804 >UniRef50_UPI00006CB7E3 Cluster: Viral A-type inclusion protein repeat containing protein; n=1; Tetrahymena thermophila SB210|Rep: Viral A-type inclusion protein repeat containing protein - Tetrahymena thermophila SB210 Length = 2645 Score = 125 bits (302), Expect = 9e-27 Identities = 267/1421 (18%), Positives = 622/1421 (43%), Gaps = 133/1421 (9%) Query: 235 EKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXX 294 EK + +E + +R ++LE N+ L+ ++ + +L +ELE Sbjct: 1277 EKTNKIIQLEQR-LRDNTLEYQNQALQQKVNLLTEQIERLVRELENARNELIQVSRKC-- 1333 Query: 295 LAKQSIEPSCEEKTEIEEKGSLE--IANMTELTKKIELLEHLNCQIRQTNKELENKLATM 352 QS+E E++T ++ E IA + +++ +++++ + +N++A + Sbjct: 1334 ---QSLE--IEKQTWDAQRAQYEQTIAQLHAEIQRLREQADEGEKVKRSKQNQDNRVAQL 1388 Query: 353 GTESKAVSSPSKK----GSPLISRKSGRN-TASKMKSPWSQLSSETLNQDTDKKINKNEI 407 E+K + +K + L+ + S T ++++ + + + NQ+ ++N + Sbjct: 1389 EAENKYLQDQLEKLRNDNNQLLQQVSQLTLTLQQLQAKLNDNTLQIQNQELQNRLNA-KT 1447 Query: 408 AKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIH 467 A+LE V Q L + +I+E G + L+ Q+ ++ Sbjct: 1448 AELERVAQELQR----LSQLINELTLEVNRLKSENAGFEVTKRALEGRIQELASRLEML- 1502 Query: 468 VGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMI 527 T ++N + ++ +L +L+ + + +L A L++ + ++I Sbjct: 1503 ----TGEINRLNQLNGELSYKLSSS---ATINERYARLSDAYVLQCALSESLSKKVSDLI 1555 Query: 528 KVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHL-SQKVAELEEEK---GNLQL 583 ++ K+ Q+ S N+ +++ +L L ++K EL+ K N+ + Sbjct: 1556 GFQNEADEHRKRAQRQ-------SQDNEALIQRINQLEQLLAEKDRELQNLKVASQNVSI 1608 Query: 584 HLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDK 643 + + ++ K++ E+EN+ R K I+ L + ++++LQ + + E++ Sbjct: 1609 LQMQLQQSNQDKENLIKRIRELENILGERDKEIAGLRNAN----SQVNLLQIQIQQYENQ 1664 Query: 644 LADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDK 703 + D+ + +D E+++V + + S +E+ + + ++L I+ ++ Sbjct: 1665 INDLKRRHAD----ELENVKRQYEGLRQSTVNREINELTVKFNIRIQELEREIQKYKSLS 1720 Query: 704 EDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLY 763 E N+L+ Q+N +L +L + AE + + +EQ K +++ G ++ + Sbjct: 1721 EQYENELRAQRQQNSELLQRL--VDAENRAR-----DSDEQVK-RSRAG-QQQVNNLEEN 1771 Query: 764 IENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDEL 823 + + +EL K K+ + + A +E ++ L + ++L + L+EK ++ +E E Sbjct: 1772 LRFVTAELEKQKNLLAEEKNKNAQLESQKSILAMEIERLNTILKEKLILIEDFQRREAEY 1831 Query: 824 VNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLE---ENQNLQISLSDMQQHYNALV 880 N+L L V + +++ N ++Q N L + E Q L L ++QQ L Sbjct: 1832 ENQLRELQARLASVAELESKLQFFNNQIQTLNFSLEQKEKEKQALGQHLVELQQTIEQL- 1890 Query: 881 EKANRTDLAESESTKYQTQ--LRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIES 938 +A T +A + KYQ + R+ E+ +R+ + QT+ + + + ++F Q E+ Sbjct: 1891 -RAENTQVA---AFKYQVENLSRENEALKQRLVEQQQTIDKLRAEASQFASLKF--QAEN 1944 Query: 939 AIRDKKVLNEKYEKNIEYVTQLEAQLQEY---KNNIENLNMNVEELNKMNLELIDKHVQK 995 R+ + L ++ + + V +L A+ ++ + +ENL E L K L + + + Sbjct: 1945 LQRENEALKQRLVELQQTVDKLRAEAAQFGSLQYQVENLTRENEAL-KQRLAQTAETLSQ 2003 Query: 996 QQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTT 1055 Q Q+ + + ++L L Q + E + K+ ++ + D + + Q Sbjct: 2004 QVAQNSELQRRVQQLESELQLLKMQLEGE--REDNKVKRSRNDKNN--EDLQKVIQQLQQ 2059 Query: 1056 KLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKE-----TKLTFEMNIPKTE 1110 ++EN+ E+Q +++ + + +QIL E++D I++L K ++ + Sbjct: 2060 EIENLRREIQARDQKIAELSNASYTIQILQHEKEDLIRKLDAISQVYAKSQTDLQNSLQK 2119 Query: 1111 GMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQE-----------EEEFIQERSVLQE 1159 +++S+ +E SD+AN K QE + +F QE+ + Sbjct: 2120 VVVLSARVE-SSDEANKNLTAQVQILSQSLQNKDQELRNLMIAYQELQVKFGQEQENSRR 2178 Query: 1160 QSAKLNTE-LQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLE-QLNTE-NDNLLST 1216 S+ +++ +QE ++ L EL + + I ++K ++E QL+ E L + Sbjct: 2179 SSSMASSKFIQERVQLEAEINRLKNELAIIEHKHNLTIEEIKRQMEVQLSEELRKQLAAA 2238 Query: 1217 VAELRSSISSAVD--QRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDS 1274 AE ++ A++ Q+ +E + + Q+E D K + +L +Q+ + EQ L Sbjct: 2239 KAEYERRLNDALNAQQQQYEDDRVKRSKQQQKENDDLKNQLQLTIQM-----QLEQQLAE 2293 Query: 1275 VQSSTQEETNKIVTMEQVTSLQ-NKLQDKEEH-LRNLQE--KYADVINQIEILR----SE 1326 V++ + E ++ + + +L+D+ +H L N +E K+ D+I Q+++ + SE Sbjct: 2294 VKARMEAERRRLEEENAMLRARVQQLEDQLQHALVNEEEILKFKDLIQQLQMQKLKDISE 2353 Query: 1327 IEDEKVAF-XXXXXXXXXXXXXXXXDLRTENQSYKQMQEQ--SILNI-NEENAQLKKSSX 1382 ++ + + +TE Q + +Q IL + ++EN +L+ ++ Sbjct: 2354 LQQKLEEYRSLHVNAGGSLQDAIKTSFQTEIQQLRDKVQQLNQILEVKSKENNELQSANL 2413 Query: 1383 XXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLV 1442 + + + + + T ++E ++ Q +++ T R +E +L Sbjct: 2414 NLMRERSEIKKSMTSSNSNI-QFTMEIESLKRQLIQ-SNDRTQEYEARIKSYEG---KLN 2468 Query: 1443 EYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLN 1502 +YE ++ + E + IL +K E N + M + + + + + + L+ + + V L Sbjct: 2469 QYELQLSQVVNELKQTQDILNIKKMERDNAFNQMD-QLKSQTLSMSQALS-QGSNDVDL- 2525 Query: 1503 KQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFAS 1562 + + L K + E + + L N+ + LN + T + M ++ S K ++ + Sbjct: 2526 QNIVFLKKEI-ENLQNLKHLFIFLNNK----LNLNQKRTVEKEMYKSQSEKNYAELNRKN 2580 Query: 1563 DTKQGRDEQLDNT-----MNKELLDAVPRAELDLAMYMLHQ 1598 + + E+L+N N + A+ + ++L ++L++ Sbjct: 2581 EELVRKIEELNNVKLQYQQNNNKIYALEKEVINLLFFILNK 2621 Score = 125 bits (301), Expect = 1e-26 Identities = 253/1329 (19%), Positives = 541/1329 (40%), Gaps = 82/1329 (6%) Query: 305 EEKTEIEEKGSLEIANMTELTKKIELL-EHLNCQIRQTN-------KELENKLATMGTES 356 EE+ +EEK + L K++E+ +H N +I+Q++ +EL+NK+A ++ Sbjct: 306 EERARMEEKIVQAQTEIMRLEKQVEIWKDHCN-KIQQSHPNQDQRIQELQNKIADYESKI 364 Query: 357 KAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKIN-KNEIAKLEMVIQ 415 ++ +++ + LI K K S S + T + ++ KN+++ E++I Sbjct: 365 NQLAIDNQRLNQLIQIKDEEADKIKRASRQSNVDQRTYDSLQNENYQLKNDLSSKELLIV 424 Query: 416 SLNKDLVDKEYVISEKDTXXXXXXXXXXGK-DTLIAQLQLEHQQHMEGPSLIHV---GTN 471 LN+ + D E + + D + + L+ +Q++ + + TN Sbjct: 425 QLNQRIRDFEGNGQKTTQELTQKIFILTNELDNVTSHLKARNQEYEDLSKRYNQLLQQTN 484 Query: 472 TEDVNEIAKVQEQLKQ--ELNDEIKDVNV--KDLIEKLKSAEEQITQLNDEIDAANKNMI 527 + K QEQL + +L E++ + + +++K + L + +I Sbjct: 485 QMTQSGEFKYQEQLSKSIQLGQEVEKLAALTRAQADEIKDWRNKYADLESRYNQ-QIILI 543 Query: 528 KVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVD 587 ++N ++ +Q+Q D + + E + L +QK EL+ L+ + Sbjct: 544 SQQTNQEVYRRQIQDLEDQLRRKTAEANEWQQSFTNLQ--AQKERELKNLMETLKDEIRK 601 Query: 588 YDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELH-------ILQQKYDEV 640 S +++D Y K+ + L +++ ++ + +K + ++ L + ++K + Sbjct: 602 SSSSLNLQND-YNKLKDQVQLLTHQIEQLNKISIEKDNEIRLLRNQAGNDALYREKIINM 660 Query: 641 EDKLADI-SQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDL 699 E+KL + S+LQ+ ++IK + L ++ + IE + T++ L Sbjct: 661 ENKLVQLTSELQNQINLNQIKESEIVSLKRQLEEARGRYSADIETQLIQLRSQVTTLQQL 720 Query: 700 ENDKEDIMNKLQNYIQENMDLTDKLEK-MSAEKISELLAKINHEEQ--SKIQTQFGIDAK 756 K++I+N LQ + E+ D + +K +++ + ++ + Q +K+ + + Sbjct: 721 LQQKDEIINDLQRKLAEHEDPVKRSKKDNETQRLLNQIQELTFDNQRLTKLNNEQAVTID 780 Query: 757 IQERDLY-IENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSE 815 RDL ++ + + +I L I V+E + ++ + D L L E + + Sbjct: 781 QLRRDLINLQQQSQNVVEQNRKIEALLYQIEVLEKQLRAVAEERDNLKRQLLETETLRQK 840 Query: 816 YTIQEDELVNRLAVLMDHDRVVEKQLLEIEHEN-KELQKKNQILLEENQNLQIS-LSDMQ 873 QE R L + R + QL + EN K K++QI Q ++I+ L ++ Sbjct: 841 LKEQE----ARELYLQEQIRNLVAQLENAQTENVKRAGKESQI---NQQQVRINELENLI 893 Query: 874 QHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFN 933 Q +EK N + + + + +S + + + I+ EI+ L Sbjct: 894 QVLRGEIEKLNNIIRMKDQDLDSLKRESNRKSVVDAEKQQLENKILLLASEIDRLSRSLQ 953 Query: 934 TQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNL-ELIDKH 992 + E R K ++ EK + ++ + QL++++ ++ LN ++ L + N+ +L D++ Sbjct: 954 DKHEEVNRLKSIIIEK-DSQLQSLPQLQSRIALLQDENNRLNAQIKLLTEENIRKLTDEN 1012 Query: 993 VQKQQ--TQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDY---E 1047 +Q +Q + D+ Q NK+ L+ ++ E + + + ++S + ++DY + Sbjct: 1013 IQLRQRLNEMADFERQKNELENKIQLLISER-ERLNGIITTMTQEKLSLQAQLNDYAQGD 1071 Query: 1048 SKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIP 1107 + ++E+++ + QR+ + L + N EL+ +++ D + E L ++N+ Sbjct: 1072 RIRKELEYQIESLKRDKQRLEEGLTNLANENNELRSRLQQLGDMDRVRGE--LENKINLL 1129 Query: 1108 KTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTE 1167 E + + + +++ N L+ E + E++ +LN Sbjct: 1130 IQENDRLRAALAAKNEE-NTKLILKINDLSNLEKLRADLEGRI----KIYGEENQRLNDI 1184 Query: 1168 LQECYTKIIQLETLNTELTGHDVVNQEQIN-QLKSKLEQLNTENDNLLSTVAELRSSISS 1226 ++ L+T +L+ N EQ+ L+ ++ L EN L V + Sbjct: 1185 IRRLTEDNTSLQTRIAQLS-----NIEQVRITLEGQINLLVAENKRLNDLVRAKDEELVQ 1239 Query: 1227 AVD-QRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNK 1285 D + FE+ +L R + Q +K QL ++ +T E N+ Sbjct: 1240 IRDIKTRFELFQLRNIDALARLTITMAELERVSAQSVEKTNKIIQLEQRLRDNTLEYQNQ 1299 Query: 1286 IVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIE--DEKVAFXXXXXXXXX 1343 + ++V L +++ L N + + V + + L E + D + A Sbjct: 1300 AL-QQKVNLLTEQIERLVRELENARNELIQVSRKCQSLEIEKQTWDAQRAQYEQTIAQLH 1358 Query: 1344 XXXXXXXDLRTENQSY---KQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEA 1400 + E + KQ Q+ + + EN L+ +V+ Sbjct: 1359 AEIQRLREQADEGEKVKRSKQNQDNRVAQLEAENKYLQDQLEKLRNDNNQLLQQVSQLTL 1418 Query: 1401 KVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELA 1460 + +L Q +L D+ + + E L + E E V Q+L + I +LT E Sbjct: 1419 TLQQL--QAKLNDNTLQIQNQELQNRLNAKTAELERVAQELQRLSQLINELTLE------ 1470 Query: 1461 ILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTN 1520 + RLK ENA +E ++ E +L L + E LN+ EL+ L A N Sbjct: 1471 VNRLK-SENAG-FEVTKRALEGRIQELASRLEMLTGEINRLNQLNGELSYKLSSS-ATIN 1527 Query: 1521 EMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKEL 1580 E L + + L++ ++ + + ++ +H A Q + + E Sbjct: 1528 ERYARLSDAYVLQCALSESLSKKVSDLIGFQNEADEHRKRAQRQSQDNEALIQRINQLEQ 1587 Query: 1581 LDAVPRAEL 1589 L A EL Sbjct: 1588 LLAEKDREL 1596 Score = 118 bits (283), Expect = 2e-24 Identities = 235/1202 (19%), Positives = 515/1202 (42%), Gaps = 118/1202 (9%) Query: 476 NEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNH-- 533 N +A+++ + + K+ + ++ E I L EI+ N N+I++K Sbjct: 857 NLVAQLENAQTENVKRAGKESQINQQQVRINELENLIQVLRGEIEKLN-NIIRMKDQDLD 915 Query: 534 KLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSG-- 591 LK + +K++ + K NK I+ L E+ LS+ + + EE L+ +++ DS Sbjct: 916 SLKRESNRKSVVDAEKQQLENK-ILLLASEIDRLSRSLQDKHEEVNRLKSIIIEKDSQLQ 974 Query: 592 ---------RMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVED 642 +++ + + +++ L E ++ ++ Q + E+ +++ +E+E+ Sbjct: 975 SLPQLQSRIALLQDENNRLNAQIKLLTEENIRKLTDENIQLRQRLNEMADFERQKNELEN 1034 Query: 643 KL----ADISQLQSDQVCSEIKSVHLEEQIDALSAS---KKELALVIENLKLDKEQLYGT 695 K+ ++ +L + + L+ Q++ + +KEL IE+LK DK++L Sbjct: 1035 KIQLLISERERLNGIITTMTQEKLSLQAQLNDYAQGDRIRKELEYQIESLKRDKQRLEEG 1094 Query: 696 IKDLENDKEDIMNKLQ---NYIQENMDLTDKLEKMSAE--KISELLAKINHEEQSKIQTQ 750 + +L N+ ++ ++LQ + + +L +K+ + E ++ LA N EE +K+ + Sbjct: 1095 LTNLANENNELRSRLQQLGDMDRVRGELENKINLLIQENDRLRAALAAKN-EENTKLILK 1153 Query: 751 FGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEK- 809 + + ++E + Y RL + I + + SL+ + QL + Q + Sbjct: 1154 IN---DLSNLEKLRADLEGRIKIYGEENQRLNDIIRRLTEDNTSLQTRIAQLSNIEQVRI 1210 Query: 810 -QKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQIS 868 + + E++ +N L D + V Q+ +I+ + Q +N ++ L I+ Sbjct: 1211 TLEGQINLLVAENKRLNDLVRAKDEELV---QIRDIKTRFELFQLRN---IDALARLTIT 1264 Query: 869 LSDMQQHYNALVEKANRTDLAE----SESTKYQTQLRDLESNLKRITHEHQTLIVQKKKE 924 ++++++ VEK N+ E + +YQ Q L+ + +T + + L+ + + Sbjct: 1265 MAELERVSAQSVEKTNKIIQLEQRLRDNTLEYQNQA--LQQKVNLLTEQIERLVRELENA 1322 Query: 925 IEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNI-ENLNMNVEELNK 983 +L I+ + + +S +K+ + + + + + QL A++Q + E + + N+ Sbjct: 1323 RNEL-IQVSRKCQSLEIEKQTWDAQRAQYEQTIAQLHAEIQRLREQADEGEKVKRSKQNQ 1381 Query: 984 MN----LELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSY 1039 N LE +K++Q Q + + Q + ++++L L+Q L K+N+ + Sbjct: 1382 DNRVAQLEAENKYLQDQLEKLRNDNNQLLQQVSQLTLTLQQ-------LQAKLNDNTLQI 1434 Query: 1040 MSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDS--------KQHNEELQILVREQDDQ 1091 + + +++L T +LE + +E+QR+S QL++ K N ++ R + + Sbjct: 1435 QN--QELQNRLNAKTAELERVAQELQRLS-QLINELTLEVNRLKSENAGFEVTKRALEGR 1491 Query: 1092 IKEL--KETKLTFEMN-IPKTEGMI---ISSTIEPMSDDANNVDXXXXX-XXXXXXXLKV 1144 I+EL + LT E+N + + G + +SS+ A D KV Sbjct: 1492 IQELASRLEMLTGEINRLNQLNGELSYKLSSSATINERYARLSDAYVLQCALSESLSKKV 1551 Query: 1145 QEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETL----NTELTGHDVVNQEQINQLK 1200 + F E ++++ + + + + +I QLE L + EL V +Q ++ L+ Sbjct: 1552 SDLIGFQNEADEHRKRAQRQSQDNEALIQRINQLEQLLAEKDRELQNLKVASQ-NVSILQ 1610 Query: 1201 SKLEQLNTENDNLLSTVAELRS-------------SISSAVDQRGFEIAELWKQ--HLAQ 1245 +L+Q N + +NL+ + EL + + +S V+ +I + Q L + Sbjct: 1611 MQLQQSNQDKENLIKRIRELENILGERDKEIAGLRNANSQVNLLQIQIQQYENQINDLKR 1670 Query: 1246 READ-FQKTEHELR-VQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVT-SLQNKLQDK 1302 R AD + + + ++ S + +L QE +I + ++ +N+L+ + Sbjct: 1671 RHADELENVKRQYEGLRQSTVNREINELTVKFNIRIQELEREIQKYKSLSEQYENELRAQ 1730 Query: 1303 EEHLRNLQEKYADVINQI-----EILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTE-- 1355 + L ++ D N+ ++ RS ++V +L E Sbjct: 1731 RQQNSELLQRLVDAENRARDSDEQVKRSRAGQQQVNNLEENLRFVTAELEKQKNLLAEEK 1790 Query: 1356 NQSYKQMQEQSIL--NINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKD 1413 N++ + ++SIL I N LK+ N L EL+ Sbjct: 1791 NKNAQLESQKSILAMEIERLNTILKEKLILIEDFQRREAEYENQLRELQARLASVAELES 1850 Query: 1414 SEIYQKTHEYTI--TLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENAN 1471 + T+ +L Q+ E + + Q LVE ++ IE L E +++A + ++ EN + Sbjct: 1851 KLQFFNNQIQTLNFSLEQKEKEKQALGQHLVELQQTIEQLRAE-NTQVAAFKYQV-ENLS 1908 Query: 1472 HYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEI 1531 K+ +E+ + I++L + ++ SL Q L + E + E+Q ++ Sbjct: 1909 RENEALKQRLVEQQQTIDKLRAEASQFASLKFQAENLQRENEALKQRLVELQQTVDKLRA 1968 Query: 1532 EIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDL 1591 E ++N+ R + + Q+ + T + +Q+ N EL V + E +L Sbjct: 1969 EAAQFGSLQYQVENLTRENEALKQR----LAQTAETLSQQV--AQNSELQRRVQQLESEL 2022 Query: 1592 AM 1593 + Sbjct: 2023 QL 2024 Score = 99 bits (238), Expect = 5e-19 Identities = 187/1071 (17%), Positives = 429/1071 (40%), Gaps = 86/1071 (8%) Query: 144 VTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXX 203 + L + EKD L L+V + + + LQ+ +K+ +I+ + Sbjct: 1582 INQLEQLLAEKDRELQNLKVASQNVSILQMQLQQSNQDKENLIKRIRELEN-----ILGE 1636 Query: 204 XXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEA--NKLLE 261 + Q+ +Q E + D K+R ++E+ + L ++ N+ + Sbjct: 1637 RDKEIAGLRNANSQVNLLQIQIQQYENQINDLKRRHADELENVKRQYEGLRQSTVNREIN 1696 Query: 262 AARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANM 321 + ++ +L +E+++ +Q+ E + + E + + Sbjct: 1697 ELTVKFNIRIQELEREIQKYKSLSEQYENELRAQRQQNSE-LLQRLVDAENRARDSDEQV 1755 Query: 322 TELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASK 381 + + +L +R ELE + + E + + S L NT K Sbjct: 1756 KRSRAGQQQVNNLEENLRFVTAELEKQKNLLAEEKNKNAQLESQKSILAMEIERLNTILK 1815 Query: 382 MK----SPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXX 437 K + + +E NQ + + +A+LE +Q N + + + +K+ Sbjct: 1816 EKLILIEDFQRREAEYENQLRELQARLASVAELESKLQFFNNQIQTLNFSLEQKEKEKQA 1875 Query: 438 XXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVN 497 I QL+ E+ Q V V +++ E LKQ L V Sbjct: 1876 LGQHLVELQQTIEQLRAENTQ---------VAAFKYQVENLSRENEALKQRL------VE 1920 Query: 498 VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNF----SKVSDS 553 + I+KL++ Q L + + N+ + K +L ++Q+T+D ++ Sbjct: 1921 QQQTIDKLRAEASQFASLKFQAE----NLQRENEALKQRLVELQQTVDKLRAEAAQFGSL 1976 Query: 554 NKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSG-RMIESDVYKKMIEMENLAETR 612 ++ LT E L Q++A+ E + + +ES++ +++E E Sbjct: 1977 QYQVENLTRENEALKQRLAQTAETLSQQVAQNSELQRRVQQLESELQLLKMQLEGEREDN 2036 Query: 613 LKAISLLESQKFDLVQELHILQQKYDEV-------EDKLADISQLQSDQVCSEIKSVHLE 665 S + DL + + LQQ+ + + + K+A++S + + L Sbjct: 2037 KVKRSRNDKNNEDLQKVIQQLQQEIENLRREIQARDQKIAELSNASYTIQILQHEKEDLI 2096 Query: 666 EQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLE 725 ++DA+S + ++N L ++ + +++ ++Q Q + +L Sbjct: 2097 RKLDAISQVYAKSQTDLQNSLQKVVVLSARVESSDEANKNLTAQVQILSQSLQNKDQELR 2156 Query: 726 KMSAEKISELLAKINHEEQSKIQTQFGIDAK-IQERDLYIENIESELSKYKSRICRLE-- 782 + EL K E+++ ++ +K IQER +E+E+++ K+ + +E Sbjct: 2157 NLMI-AYQELQVKFGQEQENSRRSSSMASSKFIQER----VQLEAEINRLKNELAIIEHK 2211 Query: 783 ESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLL 842 ++ + E +R + +++L L A +EY + ++ +N + DRV K+ Sbjct: 2212 HNLTIEEIKRQMEVQLSEELRKQL---AAAKAEYERRLNDALNAQQQQYEDDRV--KRSK 2266 Query: 843 EIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRD 902 + + EN +L KNQ+ L +Q+ L A +E R E E+ + +++ Sbjct: 2267 QQQKENDDL--KNQLQL----TIQMQLEQQLAEVKARMEAERRR--LEEENAMLRARVQQ 2318 Query: 903 LESNLKRITHEHQTLIVQKK--KEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIE--YVT 958 LE L+ + ++ K ++++ +++ ++++ + + + L+ +++ T Sbjct: 2319 LEDQLQHALVNEEEILKFKDLIQQLQMQKLKDISELQQKLEEYRSLHVNAGGSLQDAIKT 2378 Query: 959 QLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALL 1018 + ++Q+ ++ ++ LN +E +K N EL ++ + +S + + N+ + Sbjct: 2379 SFQTEIQQLRDKVQQLNQILEVKSKENNELQSANLNLMRERS-----EIKKSMTSSNSNI 2433 Query: 1019 KQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHN 1078 Q EI +L +++ + +YE+++ + KL E ++ +V +L KQ Sbjct: 2434 -QFTMEIESLKRQL----IQSNDRTQEYEARIKSYEGKLNQYELQLSQVVNEL---KQTQ 2485 Query: 1079 EELQILVREQD---DQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXX 1135 + L I E+D +Q+ +LK L+ + + + I + + N+ Sbjct: 2486 DILNIKKMERDNAFNQMDQLKSQTLSMSQALSQGSNDVDLQNIVFLKKEIENLQNLKHLF 2545 Query: 1136 XXXXXXLKVQEEEEFIQE--RSVLQEQSAKLNTELQECYTKIIQLETLNTE 1184 L + ++ +E +S ++ A+LN + +E KI +L + + Sbjct: 2546 IFLNNKLNLNQKRTVEKEMYKSQSEKNYAELNRKNEELVRKIEELNNVKLQ 2596 Score = 97.1 bits (231), Expect = 4e-18 Identities = 199/1033 (19%), Positives = 447/1033 (43%), Gaps = 102/1033 (9%) Query: 547 FSKVSDSNKEIVRLTEELH-HLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEM 605 F V + ++ R+ +E + + Q +L + + N++ + G E+DV + + ++ Sbjct: 92 FRDVDEITEQFNRILKEKNDQIDQLKRQLNDPEENVKRAA---NRGGPSENDVSELIQQL 148 Query: 606 ENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEI--KSVH 663 +NL + L +S++ ++ L + Q Y+ +KL+D + L+ Q E+ ++ + Sbjct: 149 QNLN------VELTKSRQNEI--RLSAMVQNYENQINKLSD-ANLKLSQELKEVGEQNQY 199 Query: 664 LEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQ-ENMDLTD 722 L Q+ + + + I++ + + +L+ +++ + + E N N ++ +N +L + Sbjct: 200 LVSQLQGQNPESRIREIQIKHAE-ELNKLHAQLREAQLNAERNQNDQINQLRKQNQELVN 258 Query: 723 KLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLE 782 ++E++++ L+ + E +K T ++ IQ+R+ ++N +++ + R+E Sbjct: 259 EIERLTS-----LIKTLQQELSAKGDTT-QLNIIIQQRNQELDNWKNKYNLLAEERARME 312 Query: 783 ESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLL 842 E I + LE++ + + + Q+++ + EL N++A D+ E ++ Sbjct: 313 EKIVQAQTEIMRLEKQVEIWKDHCNKIQQSHPNQDQRIQELQNKIA---DY----ESKIN 365 Query: 843 EIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRD 902 ++ +N+ L + QI EE +K R + + L++ Sbjct: 366 QLAIDNQRLNQLIQIKDEE------------------ADKIKRASRQSNVDQRTYDSLQN 407 Query: 903 LESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEA 962 LK + LIVQ + I D E + + +L + + N+ + L+A Sbjct: 408 ENYQLKNDLSSKELLIVQLNQRIRDFEGNGQKTTQELTQKIFILTNELD-NV--TSHLKA 464 Query: 963 QLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKD 1022 + QEY++ + N +++ N+M K+ Q+Q ++S Q E+ KL AL + + Sbjct: 465 RNQEYEDLSKRYNQLLQQTNQMTQSGEFKY-QEQLSKS----IQLGQEVEKLAALTRAQA 519 Query: 1023 EEIIALNQKINNAQVSYMSMVSDYESKLAQ--FTTKLENMEEEMQRVSKQLLDSKQHNEE 1080 +EI K + + Y + + Q + +++++E++++R + + NE Sbjct: 520 DEIKDWRNKYADLESRYNQQIILISQQTNQEVYRRQIQDLEDQLRR------KTAEANEW 573 Query: 1081 LQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXX 1140 Q Q + +ELK T + I K+ SS++ +D D Sbjct: 574 QQSFTNLQAQKERELKNLMETLKDEIRKS-----SSSLNLQNDYNKLKDQVQLLTHQIEQ 628 Query: 1141 XLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLK 1200 K+ E++ E +L+ Q+ N L KII +E +LT ++ NQ +NQ+K Sbjct: 629 LNKISIEKD--NEIRLLRNQAG--NDALYR--EKIINMENKLVQLTS-ELQNQINLNQIK 681 Query: 1201 SKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREA---DFQK--TEH 1255 ++ + L + I + + Q ++ L +Q L Q++ D Q+ EH Sbjct: 682 E--SEIVSLKRQLEEARGRYSADIETQLIQLRSQVTTL-QQLLQQKDEIINDLQRKLAEH 738 Query: 1256 ELRVQLSAFESKYEQLLDSVQSSTQE-------ETNKIVTMEQVTSLQNKLQDKEEHLRN 1308 E V+ S +++ ++LL+ +Q T + + VT++Q+ LQ + +++ Sbjct: 739 EDPVKRSKKDNETQRLLNQIQELTFDNQRLTKLNNEQAVTIDQLRRDLINLQQQSQNVVE 798 Query: 1309 LQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSIL 1368 K ++ QIE+L ++ VA E ++ + ++ I Sbjct: 799 QNRKIEALLYQIEVLEKQL--RAVAEERDNLKRQLLETETLRQKLKEQEARELYLQEQIR 856 Query: 1369 NI--NEENAQLKK-SSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTI 1425 N+ ENAQ + R+N+ E + L ++E ++ I K + Sbjct: 857 NLVAQLENAQTENVKRAGKESQINQQQVRINELENLIQVLRGEIEKLNNIIRMKDQDLD- 915 Query: 1426 TLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYET--MQKESEIE 1483 +L + ++ V + + E +I L E + L+ K HE N ++ ++K+S+++ Sbjct: 916 SLKRESNRKSVVDAEKQQLENKILLLASEIDRLSRSLQDK-HEEVNRLKSIIIEKDSQLQ 974 Query: 1484 RVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNL 1543 + ++ + + + + N+ A++ EE + K + L + E+ + L Sbjct: 975 SLPQLQS-RIALLQDEN-NRLNAQIKLLTEENIRKLTDENIQLRQRLNEMADFERQKNEL 1032 Query: 1544 QNMVRASSSKIQK 1556 +N ++ S+ ++ Sbjct: 1033 ENKIQLLISERER 1045 Score = 61.3 bits (142), Expect = 2e-07 Identities = 102/518 (19%), Positives = 212/518 (40%), Gaps = 35/518 (6%) Query: 1052 QFTTKL-ENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTE 1110 +FTTK +N+ QR + +D + E+ +++E++DQI +LK E N+ + Sbjct: 74 RFTTKKKQNLSVSPQRGGFRDVD--EITEQFNRILKEKNDQIDQLKRQLNDPEENVKRAA 131 Query: 1111 ---GMIISSTIEPMSDDAN-NVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNT 1166 G + E + N NV+ VQ E I + L + + KL+ Sbjct: 132 NRGGPSENDVSELIQQLQNLNVELTKSRQNEIRLSAMVQNYENQINK---LSDANLKLSQ 188 Query: 1167 ELQECYTK----IIQLETLNTE--LTGHDVVNQEQINQLKSKLE--QLNTENDNLLSTVA 1218 EL+E + + QL+ N E + + + E++N+L ++L QLN E N + Sbjct: 189 ELKEVGEQNQYLVSQLQGQNPESRIREIQIKHAEELNKLHAQLREAQLNAER-NQNDQIN 247 Query: 1219 ELRSSISSAVDQ--RGFEIAELWKQHLAQREADFQKTE--HELRVQLSAFESKYEQLLDS 1274 +LR V++ R + + +Q L+ + Q + +L +++KY L + Sbjct: 248 QLRKQNQELVNEIERLTSLIKTLQQELSAKGDTTQLNIIIQQRNQELDNWKNKYNLLAE- 306 Query: 1275 VQSSTQEETNKIVTME-QVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIED---- 1329 + + EE KIV + ++ L+ +++ ++H +Q+ + + +I+ L+++I D Sbjct: 307 -ERARMEE--KIVQAQTEIMRLEKQVEIWKDHCNKIQQSHPNQDQRIQELQNKIADYESK 363 Query: 1330 -EKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXX 1388 ++A D + +++ ++ EN QLK Sbjct: 364 INQLAIDNQRLNQLIQIKDEEADKIKRASRQSNVDQRTYDSLQNENYQLKNDLSSKELLI 423 Query: 1389 XXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRI 1448 R+ D E + T +L K + + T L RN E+E++ ++ + ++ Sbjct: 424 VQLNQRIRDFEGNGQKTTQELTQKIFILTNELDNVTSHLKARNQEYEDLSKRYNQLLQQT 483 Query: 1449 EDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAEL 1508 +T E + K + E + + + ++ + N N+Q+ + Sbjct: 484 NQMTQSGEFKYQEQLSKSIQLGQEVEKLAALTRAQADEIKDWRNKYADLESRYNQQIILI 543 Query: 1509 NKALEEEV--AKTNEMQTALENQEIEIVTLNDEITNLQ 1544 ++ +EV + +++ L + E TNLQ Sbjct: 544 SQQTNQEVYRRQIQDLEDQLRRKTAEANEWQQSFTNLQ 581 Score = 37.9 bits (84), Expect = 2.3 Identities = 58/245 (23%), Positives = 103/245 (42%), Gaps = 21/245 (8%) Query: 140 QLGDVTHLSNTIKEKD----NALSVLQVKMKI-METTILDLQEKINEKDQIIEAKNKATT 194 +L D++ L ++E NA LQ +K +T I L++K+ + +QI+E K+K Sbjct: 2347 KLKDISELQQKLEEYRSLHVNAGGSLQDAIKTSFQTEIQQLRDKVQQLNQILEVKSKENN 2406 Query: 195 XXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLE 254 + K+ MT N I E + K++L I+S D R E Sbjct: 2407 ----ELQSANLNLMRERSEIKKSMTSSNSN-IQFTMEIESLKRQL---IQSND-RTQEYE 2457 Query: 255 EANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQ--SIEPSCEEKTEIEE 312 K E + L+ S++ EL+Q Q ++ ++ Sbjct: 2458 ARIKSYEGKLNQYELQLSQVVNELKQTQDILNIKKMERDNAFNQMDQLKSQTLSMSQALS 2517 Query: 313 KGS--LEIANMTELTKKIELLEHLNCQIRQTNKELE-NKLATMGTESKAVSSPSKKGSPL 369 +GS +++ N+ L K+IE L++L N +L N+ T+ E + S S+K Sbjct: 2518 QGSNDVDLQNIVFLKKEIENLQNLKHLFIFLNNKLNLNQKRTV--EKEMYKSQSEKNYAE 2575 Query: 370 ISRKS 374 ++RK+ Sbjct: 2576 LNRKN 2580 >UniRef50_O42263 Cluster: Kinesin-related protein; n=2; Xenopus|Rep: Kinesin-related protein - Xenopus laevis (African clawed frog) Length = 2954 Score = 125 bits (302), Expect = 9e-27 Identities = 234/1120 (20%), Positives = 482/1120 (43%), Gaps = 136/1120 (12%) Query: 500 DLIEKLKSA-EEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIV 558 D+ E K++ E++IT L ++ + + ++ + +LK+ ++++ + V N E+V Sbjct: 542 DMAECRKASFEKEITSLQQQLQSKEEEKKELVQSFELKIAELEEQL----SVKAKNLEMV 597 Query: 559 RLTEELHHLSQKV-AELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAI- 616 + E H ++ +V ++E+E ++ ++ SD+ ++ + L+ + + I Sbjct: 598 TNSRE-HSINAEVQTDVEKEVVRKEMSVLGDSGYNASNSDLQDSSVDGKRLSSSHDECIE 656 Query: 617 --SLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSAS 674 +LE + DL + + L +K + + K ++ ++S Q+C I + E+ +AL Sbjct: 657 HRKMLEQKIVDLEEFIENLNKKSENDKQKSSEQDFMESIQLCEAI----MAEKANAL--- 709 Query: 675 KKELALV---IENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEK 731 +ELAL+ +N+ L+ E L I DLE ++EN + T++ E + E Sbjct: 710 -EELALMRDNFDNIILENETLKREIADLERS-----------LKENQE-TNEFEILEKET 756 Query: 732 ISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDR 791 E A++ HE S + ++ ++Y +N+E +L + K+++ + E+ I + E Sbjct: 757 QKEHEAQLIHEIGS-------LKKLVENAEMYNQNLEEDL-ETKTKLLK-EQEIQLAE-- 805 Query: 792 RYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKEL 851 L ++AD LQ+K + + D L + +++ L + E ++ Sbjct: 806 ---LRKRADN----LQKKVRNFDLSVSMGDS-----EKLCEEIFQLKQSLSDAEAVTRDA 853 Query: 852 QKKNQILLEENQNLQISLSDMQQHYNALVEKANRTD-LAESESTKYQTQLRDLESNLKRI 910 QK+ L EN L+ + D YN + A+ + E+E + Y+ DL+ L+ Sbjct: 854 QKECSFLRSENLELKEKMEDTSNWYNQKEKAASLFEKQLETEKSNYKKMEADLQKELQSA 913 Query: 911 THEHQTL----------IVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQL 960 +E L + + E+E EF+ Q+E A+ +K L + EY L Sbjct: 914 FNEINYLNGLLAGKVPRDLLSRVELEKKVSEFSKQLEKALEEKNALENEVTCLSEY-KFL 972 Query: 961 EAQLQEYKNNIENLN---MNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNAL 1017 +++ KN I + M +++ + + +I K Q QS + Q +E+ + Sbjct: 973 PNEVECLKNQISKASEEIMLLKQEGEHSASIISKQEIIMQEQS-EQILQLTDEVTHTQSK 1031 Query: 1018 LKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQH 1077 ++Q +E+ + + + ++ Y+ S+ E L + +EN++ M+ V ++ D+K Sbjct: 1032 VQQTEEQYLEMKKMHDDLFEKYIRNKSEAEDLLRE----MENLKGTMESVEVKIADTK-- 1085 Query: 1078 NEELQILVREQDDQIKELK---ETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXX 1134 EL+ +R+++ + E K + T P ++ + S +E S D ++ Sbjct: 1086 -HELEETIRDKEQLLHEKKYFFQAMQTIFPITPLSDSLPPSKLVEGNSQDPIEINDYHNL 1144 Query: 1135 XXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTE---------- 1184 + E ER+ L+EQ LNT+LQ + I+ L Sbjct: 1145 IALATERNNIMVCLE--TERNSLKEQVIDLNTQLQSLQAQSIEKSDLQKPKQDLEEGEVK 1202 Query: 1185 -------LTGHDVVNQEQINQLK-------SKLEQLNTENDNLLSTVAELRSS---ISSA 1227 L GH +Q I +L+ KL+ L E N+ EL+++ + + Sbjct: 1203 LLLEMELLKGHLTDSQLSIEKLQLENLEVTEKLQTLQEEMKNITIERNELQTNFEDLKAE 1262 Query: 1228 VDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLD-SVQSSTQEE---- 1282 D +++E +Q + + + + + + ELR Q +S +QLLD SV S+ Sbjct: 1263 HDSLKQDLSENIEQSI-ETQDELRAAQEELREQKQLVDSFRQQLLDCSVGISSPNHDAVA 1321 Query: 1283 TNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRS---EIEDEKVAFXXXXX 1339 + V++ +V SLQ+++ E LQ +++++E+LR+ +E E + Sbjct: 1322 NQEKVSLGEVNSLQSEMLRGERD--ELQTSCKALVSELELLRAHVKSVEGENLEITKKLN 1379 Query: 1340 XXXXXXXXXXXDLRTENQSYKQMQE-QSILNINEENAQLKKSSXXXXXXXXXXXXRVNDA 1398 + + ++E + L E K++ V++ Sbjct: 1380 GLEKEILGKSEESEVLKSMLENLKEDNNKLKEQAEEYSSKENQFSLEEVFSGSQKLVDEI 1439 Query: 1399 E---AKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEK 1455 E A++ +LE+KD + ++ L + + E Q ++E+ D E Sbjct: 1440 EVLKAQLKAAEERLEIKDRDYFELVQTANTNLVE--GKLETPLQ--ADHEEDSIDRRSE- 1494 Query: 1456 ESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAE-LNKALEE 1514 E E+ +L K+ N E +Q+E ++E +E L ++ SV L + + L L E Sbjct: 1495 EMEIKVLGEKLERNQYLLERLQEE-KLELSNKLEILQKEMETSVLLKDDLQQKLESLLSE 1553 Query: 1515 EVAKTNEMQTALENQ---EIEIVTLNDEITNLQNMVRASS 1551 + + T L++ + ++ E+ +N+ A+S Sbjct: 1554 NIILKENIDTTLKHHSDTQAQLQKTQQELQLAKNLAIAAS 1593 Score = 112 bits (270), Expect = 7e-23 Identities = 254/1355 (18%), Positives = 560/1355 (41%), Gaps = 126/1355 (9%) Query: 213 DTKQQMTKMQEN--FIAMEAEW-KDEKQRLLKDIESKDVRISSLEEANKLLEA---ARFE 266 D ++ + + QE F +E E K+ + +L+ +I S + + E N+ LE + + Sbjct: 735 DLERSLKENQETNEFEILEKETQKEHEAQLIHEIGSLKKLVENAEMYNQNLEEDLETKTK 794 Query: 267 ISLEHS-KLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELT 325 + E +LA+ ++ ++ E CEE ++++ S A + Sbjct: 795 LLKEQEIQLAELRKRADNLQKKVRNFDLSVSMGDSEKLCEEIFQLKQSLSDAEAVTRDAQ 854 Query: 326 KKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLIS--RKSGRNTASKMK 383 K+ L N ++++ ++ N + KA S K+ S +K + +++ Sbjct: 855 KECSFLRSENLELKEKMEDTSN---WYNQKEKAASLFEKQLETEKSNYKKMEADLQKELQ 911 Query: 384 SPWSQLSSETLNQDTDKKINKNEIAKLEMV--IQSLNKDLVDKEYVISEKDTXXXXXXXX 441 S +++++ LN K+ ++ ++++E+ + +K L E + EK+ Sbjct: 912 SAFNEINY--LNGLLAGKVPRDLLSRVELEKKVSEFSKQL---EKALEEKNALENEVTCL 966 Query: 442 XXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVN--VK 499 K L++Q ++ + E I QE + QE +++I + V Sbjct: 967 SEYKFLPNEVECLKNQISKASEEIMLLKQEGEHSASIISKQEIIMQEQSEQILQLTDEVT 1026 Query: 500 DLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQK---TIDNFS-KVSDSNK 555 K++ EEQ ++ D + I+ KS + L++M+ T+++ K++D+ Sbjct: 1027 HTQSKVQQTEEQYLEMKKMHDDLFEKYIRNKSEAEDLLREMENLKGTMESVEVKIADTKH 1086 Query: 556 EI---VRLTEELHH-------LSQKVAELEEEKGNLQ-LHLVDYDSGRMIESDVYKKMIE 604 E+ +R E+L H Q + + +L LV+ +S IE + Y +I Sbjct: 1087 ELEETIRDKEQLLHEKKYFFQAMQTIFPITPLSDSLPPSKLVEGNSQDPIEINDYHNLIA 1146 Query: 605 MENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHL 664 LA R + LE+++ L +++ L + ++ + + S LQ + E V L Sbjct: 1147 ---LATERNNIMVCLETERNSLKEQVIDLNTQLQSLQAQSIEKSDLQKPKQDLEEGEVKL 1203 Query: 665 EEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKL 724 +++ L + L IE L+L+ ++ ++ L+ + ++I I+ N +L Sbjct: 1204 LLEMELLKGHLTDSQLSIEKLQLENLEVTEKLQTLQEEMKNIT------IERN-ELQTNF 1256 Query: 725 EKMSAEKISELLAKINHEEQSKIQTQFGIDA---KIQERDLYIENIESELSKYKSRICRL 781 E + AE S L ++ + I+TQ + A +++E+ +++ +L I Sbjct: 1257 EDLKAEHDS-LKQDLSENIEQSIETQDELRAAQEELREQKQLVDSFRQQLLDCSVGISSP 1315 Query: 782 EESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQL 841 AV + SL + + L S + ++ E LV+ L +L H + VE + Sbjct: 1316 NHD-AVANQEKVSLG-EVNSLQSEMLRGER--DELQTSCKALVSELELLRAHVKSVEGEN 1371 Query: 842 LEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLR 901 LEI + L+K+ EE++ L+ L ++++ N L E+A E S + Q L Sbjct: 1372 LEITKKLNGLEKEILGKSEESEVLKSMLENLKEDNNKLKEQAE-----EYSSKENQFSLE 1426 Query: 902 DLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLE 961 ++ S +++ E + L Q K E LEI+ E + E +E T L+ Sbjct: 1427 EVFSGSQKLVDEIEVLKAQLKAAEERLEIKDRDYFELV---QTANTNLVEGKLE--TPLQ 1481 Query: 962 AQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQK 1021 A +E ++++ EE M ++++ + +++ Q E+ + NKL L K+ Sbjct: 1482 ADHEE-----DSIDRRSEE---MEIKVLGEKLERNQYLLERLQEEKLELSNKLEILQKEM 1533 Query: 1022 DEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSK-QHNEE 1080 + ++ + D + KL + EN+ + K+ +D+ +H+ + Sbjct: 1534 ETSVL---------------LKDDLQQKLESLLS--ENI------ILKENIDTTLKHHSD 1570 Query: 1081 LQILVREQDDQIKELKETKLTFEMNIPKTEGMIISS-TIEPMSDDANNVDXXXXXXXXXX 1139 Q +++ +++ K + N P T+ S+ + P+ + Sbjct: 1571 TQAQLQKTQQELQLAKNLAIAASDNCPITQEKETSADCVHPLEE--------KILLLTEE 1622 Query: 1140 XXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQ----LETLNTELTGHDVVNQ-- 1193 K E+E+ + E++ L++ +L E++ +I+ LE+L E HD Q Sbjct: 1623 LHQKTNEQEKLLHEKNELEQAQVELKCEVEHLMKSMIESKSSLESLQHE--KHDTEQQLL 1680 Query: 1194 ---EQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWK-QHLAQREAD 1249 +Q+ + + ++L +++L + V L+ +I ++ + + K Q L + Sbjct: 1681 ALKQQMQVVTQEKKELQQTHEHLTAEVDHLKENIELGLNFKNEAQQKTTKEQCLLNENKE 1740 Query: 1250 FQKTEHELRVQLSAFESKY---EQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHL 1306 ++++H L+ ++ E L++++ S Q+ N ME V +L++ + + Sbjct: 1741 LEQSQHRLQCEIEELMKSLKDKESALETLKESEQKVINLNQEMEMVMLEMEELKNSQRTV 1800 Query: 1307 RNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQS 1366 +++ D + + + E +D+ + + ++ Q Sbjct: 1801 IAERDQLQDDLRESVEMSIETQDDLRKAQEALQQQKDKVQELTSQISVLQEKISLLENQM 1860 Query: 1367 ILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTIT 1426 + N+ L + + + E LE + + + TI Sbjct: 1861 LYNVATVKETLSERD-DLNQSKQHLFSEIETLSLSLKEKEFALEQAEKDKADAARK-TID 1918 Query: 1427 LTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVK 1486 +T++ N+ +QL++ +++ YE+ES L + ++ N H K ++ K Sbjct: 1919 ITEK---ISNIEEQLLQQATNLKETLYERES-LIQCKEQLALNTEHLRETLKSKDLALGK 1974 Query: 1487 LIEELNVKITESVSLNKQVAELNKALEEEVAKTNE 1521 + +E + + ++L ++++ L + + E V E Sbjct: 1975 MEQERDEAANKVIALTEKMSSLEEQINENVTTLKE 2009 Score = 111 bits (267), Expect = 2e-22 Identities = 281/1464 (19%), Positives = 613/1464 (41%), Gaps = 168/1464 (11%) Query: 217 QMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQ 276 + ++Q NF ++AE KQ L ++IE I + +E E R + L S Q Sbjct: 1248 ERNELQTNFEDLKAEHDSLKQDLSENIEQS---IETQDELRAAQEELREQKQLVDSFRQQ 1304 Query: 277 ELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEI--EEKGSLEIANMTELTKKIELLEHL 334 L+ K S+ ++E+ E+ L+ + L ++ELL Sbjct: 1305 LLDCSVGISSPNHDAVANQEKVSLGEVNSLQSEMLRGERDELQ-TSCKALVSELELLRAH 1363 Query: 335 NCQIRQTNKELENKLATMGTESKAVSSPSKK-GSPLISRKSGRNT----ASKMKSPWSQL 389 + N E+ KL + E S S+ S L + K N A + S +Q Sbjct: 1364 VKSVEGENLEITKKLNGLEKEILGKSEESEVLKSMLENLKEDNNKLKEQAEEYSSKENQF 1423 Query: 390 SSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLI 449 S E + + K +++ E+ K ++ ++ D++Y + GK L Sbjct: 1424 SLEEVFSGSQKLVDEIEVLKAQLKAAEERLEIKDRDYF----ELVQTANTNLVEGK--LE 1477 Query: 450 AQLQLEHQQ-----HMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIK--------DV 496 LQ +H++ E + +G E + + ++ K EL+++++ V Sbjct: 1478 TPLQADHEEDSIDRRSEEMEIKVLGEKLERNQYLLERLQEEKLELSNKLEILQKEMETSV 1537 Query: 497 NVKD-LIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNK 555 +KD L +KL+S + L + ID K+ ++ + K +Q + N + + N Sbjct: 1538 LLKDDLQQKLESLLSENIILKENIDTTLKHHSDTQAQLQ-KTQQELQLAKNLAIAASDNC 1596 Query: 556 EIVRLTEE----LHHLSQKVAELEEE---KGNLQLHLVDYDSGRMIESDVYKKMIEMENL 608 I + E +H L +K+ L EE K N Q L+ ++ + ++ V K E+E+L Sbjct: 1597 PITQEKETSADCVHPLEEKILLLTEELHQKTNEQEKLL-HEKNELEQAQVELKC-EVEHL 1654 Query: 609 AETRLKAISLLES---QKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLE 665 ++ +++ S LES +K D Q+L L+Q+ V + ++ Q + + +E+ HL+ Sbjct: 1655 MKSMIESKSSLESLQHEKHDTEQQLLALKQQMQVVTQEKKELQQTH-EHLTAEVD--HLK 1711 Query: 666 EQID--------ALSASKKELALVIENLKLDK---------EQLYGTIKDLENDKEDIMN 708 E I+ A + KE L+ EN +L++ E+L ++KD E+ E + Sbjct: 1712 ENIELGLNFKNEAQQKTTKEQCLLNENKELEQSQHRLQCEIEELMKSLKDKESALETLKE 1771 Query: 709 KLQNYIQENMDLTDKLEKMSAEKISE---------LLAKINHEEQSKIQTQFGI----DA 755 Q I N ++ + +M K S+ L + + I+TQ + +A Sbjct: 1772 SEQKVINLNQEMEMVMLEMEELKNSQRTVIAERDQLQDDLRESVEMSIETQDDLRKAQEA 1831 Query: 756 KIQERDLYIENIESELSKYKSRICRLE-----------ESIAVMEDRRYSLER---KADQ 801 Q++D ++ + S++S + +I LE E+++ +D S + + + Sbjct: 1832 LQQQKDK-VQELTSQISVLQEKISLLENQMLYNVATVKETLSERDDLNQSKQHLFSEIET 1890 Query: 802 LGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEE 861 L L+EK+ A + + + + + + +E+QLL+ KE + + L++ Sbjct: 1891 LSLSLKEKEFALEQAEKDKADAARKTIDITEKISNIEEQLLQQATNLKETLYERESLIQC 1950 Query: 862 NQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQK 921 + L ++ +++ + + + E+ L + S+L+ +E+ T + + Sbjct: 1951 KEQLALNTEHLRETLKSKDLALGKMEQERDEAANKVIALTEKMSSLEEQINENVTTLKEG 2010 Query: 922 KKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEEL 981 + E E ++ ++ +S+ + +++ K+++ + + E ++ E N I+NL + L Sbjct: 2011 EGEKETFYLQRPSKQQSSSQMEELRESLKTKDLQ-LEEAEKEISEATNEIKNLTAKISSL 2069 Query: 982 NK---MNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVS 1038 + N ++++ V +++ +Q ++E+ +L+ LK +D ++ + A Sbjct: 2070 EEEILQNASILNEAVSERENLRHS-KQQLVSELEQLSLTLKSRDHAFAQSKREKDEAVNK 2128 Query: 1039 YMSMVSDYE---SKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKEL 1095 S+ + + ++ +F E+++E+ +S++L K ELQ+L ++++D +L Sbjct: 2129 IASLAEEIKILTKEMDEFRDSKESLQEQSSHLSEELCTYKT---ELQMLKQQKEDINNKL 2185 Query: 1096 KE-TKLTFEM--NIPKTEGMIISSTIEPMSDDANNVDX--XXXXXXXXXXXLKVQEEEEF 1150 E K E+ ++ + + +E ++ N + L++ + E Sbjct: 2186 AEKVKEVDELLQHLSSLKEQLDQIQMELRNEKLRNYELCEKMDIMEKEISVLRLMQNEPQ 2245 Query: 1151 IQERSVLQEQSA--KLNTELQECYTKIIQ--------LETLNTELTGHDVVNQEQINQLK 1200 +E V + N E+QE KI L +L++EL ++ + +K Sbjct: 2246 QEEDDVAERMDILESRNQEIQELMEKISAVYSEQHTLLSSLSSELQKETEAHKHCMLNIK 2305 Query: 1201 SKLEQLNTENDNLLSTV-AELRSSISSAVDQRG--FEIAELWKQH--LAQREADF---QK 1252 L + + L T +L + + + +++ + A + + H + E D QK Sbjct: 2306 ESLSSTLSRSFGSLQTEHVKLNTQLQTLLNKFKVVYRTAAVKEDHSLIKDYEKDLAAEQK 2365 Query: 1253 TEHELRVQLSAFESKYEQLLDSVQS----------------------STQEETNKI-VTM 1289 ELR+QL E + DS S Q++ +++ V + Sbjct: 2366 RHDELRLQLQCLEQHGRKWSDSASEELKFCEIEFLNELLFKKANIIQSVQDDFSEVQVFL 2425 Query: 1290 EQVTS-LQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXX 1348 QV S LQ +L+ K+ ++ L+E + D+ + L ++ E Sbjct: 2426 NQVGSTLQEELEHKKGFMQWLEE-FGDLHVDAKKLSEGMQQENRRIASTIQLLTKRLKAV 2484 Query: 1349 XXD-LRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTH 1407 ++ E Y E + E+N +L + + + A++L + Sbjct: 2485 VQSKIQREITVYLNQFEAKLQEKKEQNKELMRRMEHHGPSASV----MEEENARLLGILK 2540 Query: 1408 QLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMH 1467 ++ + ++ + L D+ + +++ + ++ L+ E+EL +++K+ Sbjct: 2541 TVQDESKKLQSRIKMLENELNLVKDDAMHKGEKVAILQDKL--LSRNAEAELNAMQVKLT 2598 Query: 1468 ENANHYETMQKESE-IER------VKLIEELNVKITESVSLNKQVAELNKALEEEVAKTN 1520 + ++ + KE E +++ V EE++ T+ V + + + +KA ++E+A Sbjct: 2599 KKQDNLQAAMKEIENLQKMVAKGAVPYKEEIDNLKTKVVKIEMEKIKYSKATDQEIA--- 2655 Query: 1521 EMQTALENQEIEIVTLNDEITNLQ 1544 +++ LE++E + L +E+ Q Sbjct: 2656 YLKSCLEDKEEGLRRLKEELRRAQ 2679 Score = 109 bits (263), Expect = 5e-22 Identities = 275/1375 (20%), Positives = 579/1375 (42%), Gaps = 118/1375 (8%) Query: 297 KQSIEPSCEEKTEIEEKGSLEIANMTE-LTKKIELLEHL-NCQIRQTNKELENKLATMGT 354 +Q ++ EEK E+ + L+IA + E L+ K + LE + N + N E++ + Sbjct: 559 QQQLQSKEEEKKELVQSFELKIAELEEQLSVKAKNLEMVTNSREHSINAEVQTDV----- 613 Query: 355 ESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTD-----KKINKNEIAK 409 E + V K+ S L SG N AS S + + L+ D +K+ + +I Sbjct: 614 EKEVVR---KEMSVL--GDSGYN-ASNSDLQDSSVDGKRLSSSHDECIEHRKMLEQKIVD 667 Query: 410 LEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVG 469 LE I++LNK + + SE+D + A LE M + Sbjct: 668 LEEFIENLNKKSENDKQKSSEQDFMESIQLCEAIMAEKANA---LEELALMRDNFDNIIL 724 Query: 470 TNTEDVNEIAKVQEQLK--QELND------EIKDVNVKDLIEK---LKSAEEQITQLNDE 518 N EIA ++ LK QE N+ E + + LI + LK E N Sbjct: 725 ENETLKREIADLERSLKENQETNEFEILEKETQKEHEAQLIHEIGSLKKLVENAEMYNQN 784 Query: 519 IDAANKNMIKVKSNHKLKLKQMQKTIDNFSK------VSDSNKEIVRLTEELHHLSQKVA 572 ++ + K+ +++L +++K DN K +S S + +L EE+ L Q ++ Sbjct: 785 LEEDLETKTKLLKEQEIQLAELRKRADNLQKKVRNFDLSVSMGDSEKLCEEIFQLKQSLS 844 Query: 573 ELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISL----LESQKFDLVQ 628 + E + Q S + ++ +KM + N + KA SL LE++K + + Sbjct: 845 DAEAVTRDAQKECSFLRSENL---ELKEKMEDTSNWYNQKEKAASLFEKQLETEKSNYKK 901 Query: 629 ELHILQQKYDEVEDKLADISQLQSDQVCSEIKS-VHLEEQIDALSASKKELALVIENLKL 687 LQ++ +++ ++ L + +V ++ S V LE+++ S + E AL +N Sbjct: 902 MEADLQKELQSAFNEINYLNGLLAGKVPRDLLSRVELEKKVSEFS-KQLEKALEEKNALE 960 Query: 688 DKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKI 747 ++ K L N+ E + N++ +E M L + E SA IS+ +I +EQS+ Sbjct: 961 NEVTCLSEYKFLPNEVECLKNQISKASEEIMLLKQEGEH-SASIISK--QEIIMQEQSEQ 1017 Query: 748 QTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQ 807 Q + ++ ++ E + + K L E + L R+ + L ++ Sbjct: 1018 ILQ--LTDEVTHTQSKVQQTEEQYLEMKKMHDDLFEKYIRNKSEAEDLLREMENLKGTME 1075 Query: 808 EKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKK--NQILLEENQNL 865 + ++ + +E + L+ H++ Q ++ L L+E N Sbjct: 1076 SVEVKIADTKHELEETIRDKEQLL-HEKKYFFQAMQTIFPITPLSDSLPPSKLVEGNSQD 1134 Query: 866 QISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHE--HQTLIVQKKK 923 I ++D E+ N E+E + Q+ DL + L+ + + ++ + + K+ Sbjct: 1135 PIEINDYHNLIALATERNNIMVCLETERNSLKEQVIDLNTQLQSLQAQSIEKSDLQKPKQ 1194 Query: 924 EIEDLEIEFNTQIE---SAIRDKKVLNEKYE-KNIEYVTQLEAQLQEYKNNIENLNMNVE 979 ++E+ E++ ++E + D ++ EK + +N+E +L+ LQE NI + N Sbjct: 1195 DLEEGEVKLLLEMELLKGHLTDSQLSIEKLQLENLEVTEKLQT-LQEEMKNI-TIERNEL 1252 Query: 980 ELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSY 1039 + N +L+ +++ +++ + + + +E+ L+++ + + + Q++ + V Sbjct: 1253 QTNFEDLKAEHDSLKQDLSENIEQSIETQDELRAAQEELREQKQLVDSFRQQLLDCSVGI 1312 Query: 1040 MSMVSDYESKLAQFTT-KLENMEEEMQRVSKQLLDS--KQHNEELQIL---VREQDDQIK 1093 S D + + + ++ +++ EM R + L + K EL++L V+ + + Sbjct: 1313 SSPNHDAVANQEKVSLGEVNSLQSEMLRGERDELQTSCKALVSELELLRAHVKSVEGENL 1372 Query: 1094 ELKETKLTFEMNI--PKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQE----E 1147 E+ + E I E ++ S +E + +D N + ++E Sbjct: 1373 EITKKLNGLEKEILGKSEESEVLKSMLENLKEDNNKLKEQAEEYSSKENQFSLEEVFSGS 1432 Query: 1148 EEFIQERSVLQEQ--SAKLNTELQE-CYTKIIQLETLNTELTGHDVVNQEQINQLKSKLE 1204 ++ + E VL+ Q +A+ E+++ Y +++Q T NT L + Q + + ++ Sbjct: 1433 QKLVDEIEVLKAQLKAAEERLEIKDRDYFELVQ--TANTNLVEGKLETPLQADHEEDSID 1490 Query: 1205 QLNTEND-NLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQ-KTEHELRVQLS 1262 + + E + +L E + + + E++ K + Q+E + + +L+ +L Sbjct: 1491 RRSEEMEIKVLGEKLERNQYLLERLQEEKLELSN--KLEILQKEMETSVLLKDDLQQKLE 1548 Query: 1263 AFESKYEQLLDSV------QSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEK--YA 1314 + S+ L +++ S TQ + K T +++ +N ++ QEK A Sbjct: 1549 SLLSENIILKENIDTTLKHHSDTQAQLQK--TQQELQLAKNLAIAASDNCPITQEKETSA 1606 Query: 1315 DVINQIE---ILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNIN 1371 D ++ +E +L +E +K +L+ E + + +S ++ Sbjct: 1607 DCVHPLEEKILLLTEELHQKTNEQEKLLHEKNELEQAQVELKCEVEHLMKSMIESKSSL- 1665 Query: 1372 EENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRN 1431 E+ Q +K +V E K L+ TH+ + + ++ E + Sbjct: 1666 -ESLQHEKHDTEQQLLALKQQMQVVTQEKKELQQTHEHLTAEVDHLKENIELGLNFKNEA 1724 Query: 1432 DEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEEL 1491 + Q L+ K +E + + E+ L + + + ET+ KESE + + L +E+ Sbjct: 1725 QQKTTKEQCLLNENKELEQSQHRLQCEIEELMKSLKDKESALETL-KESEQKVINLNQEM 1783 Query: 1492 NVKITESVSL-NKQ---VAELNKALEEEVAKTNEM-----------QTALENQEIEIVTL 1536 + + E L N Q +AE ++ L++++ ++ EM Q AL+ Q+ ++ L Sbjct: 1784 EMVMLEMEELKNSQRTVIAERDQ-LQDDLRESVEMSIETQDDLRKAQEALQQQKDKVQEL 1842 Query: 1537 NDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDL 1591 +I+ LQ + +++ +V+ +T RD+ N + L + L L Sbjct: 1843 TSQISVLQEKISLLENQMLYNVATVKETLSERDDL--NQSKQHLFSEIETLSLSL 1895 Score = 66.9 bits (156), Expect = 4e-09 Identities = 177/862 (20%), Positives = 366/862 (42%), Gaps = 102/862 (11%) Query: 141 LGDVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXX 200 L +V + T+ E+D+ Q +ET L L+ EK+ +E K Sbjct: 1861 LYNVATVKETLSERDDLNQSKQHLFSEIETLSLSLK----EKEFALEQAEKDKADAARKT 1916 Query: 201 XXXXXXXXXXXEDTKQQMTKMQENFIAMEA--EWKDE----KQRLLKDIESKDVRISSLE 254 E QQ T ++E E+ + K++ + L + ++SKD+ + +E Sbjct: 1917 IDITEKISNIEEQLLQQATNLKETLYERESLIQCKEQLALNTEHLRETLKSKDLALGKME 1976 Query: 255 EANKLLEAARFEISL--EHSKLAQELEQ--XXXXXXXXXXXXXXLAKQSIEPSCEEKTEI 310 + EAA I+L + S L +++ + L + S + S + E+ Sbjct: 1977 QERD--EAANKVIALTEKMSSLEEQINENVTTLKEGEGEKETFYLQRPSKQQSSSQMEEL 2034 Query: 311 EEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGT-ESKAVSSPSKKGSPL 369 E SL+ TK ++ LE +I + E++N A + + E + + + S + Sbjct: 2035 RE--SLK-------TKDLQ-LEEAEKEISEATNEIKNLTAKISSLEEEILQNASILNEAV 2084 Query: 370 ISRKSGRNTASKMKSPWSQLSSETLNQD-------TDKKINKNEIAKLEMVIQSLNKDLV 422 R++ R++ ++ S QLS ++D +K N+IA L I+ L K++ Sbjct: 2085 SERENLRHSKQQLVSELEQLSLTLKSRDHAFAQSKREKDEAVNKIASLAEEIKILTKEM- 2143 Query: 423 DKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQ 482 + K++ T +LQ+ QQ + + + ++V+E+ + Sbjct: 2144 --DEFRDSKESLQEQSSHLSEELCTYKTELQMLKQQKEDINN--KLAEKVKEVDELLQHL 2199 Query: 483 EQLKQELND---EIKDVNVK--DLIEKLKSAEEQITQL--------NDEIDAANKNMIKV 529 LK++L+ E+++ ++ +L EK+ E++I+ L +E D A + I Sbjct: 2200 SSLKEQLDQIQMELRNEKLRNYELCEKMDIMEKEISVLRLMQNEPQQEEDDVAERMDILE 2259 Query: 530 KSNHKLKLKQMQKTIDNFSK----VSDSNKEIVRLTEELHHLSQKVAE-----LEEEKGN 580 N +++ + M+K +S+ +S + E+ + TE H + E L G+ Sbjct: 2260 SRNQEIQ-ELMEKISAVYSEQHTLLSSLSSELQKETEAHKHCMLNIKESLSSTLSRSFGS 2318 Query: 581 LQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEV 640 LQ V ++ + +K + + E SL++ + DL E Q+++DE+ Sbjct: 2319 LQTEHVKLNTQLQTLLNKFKVVYRTAAVKEDH----SLIKDYEKDLAAE----QKRHDEL 2370 Query: 641 EDKLADISQ---LQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIK 697 +L + Q SD E+K +E + L KK A +I++++ D ++ + Sbjct: 2371 RLQLQCLEQHGRKWSDSASEELKFCEIEFLNELL--FKK--ANIIQSVQDDFSEVQVFLN 2426 Query: 698 DLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQ-----TQFG 752 + + ++ + + ++Q + D + A+K+SE + + N S IQ + Sbjct: 2427 QVGSTLQEELEHKKGFMQWLEEFGDL--HVDAKKLSEGMQQENRRIASTIQLLTKRLKAV 2484 Query: 753 IDAKIQ-ERDLYIENIESELSKYKSR----ICRLEE---SIAVMED---RRYSLERKADQ 801 + +KIQ E +Y+ E++L + K + + R+E S +VME+ R + + Sbjct: 2485 VQSKIQREITVYLNQFEAKLQEKKEQNKELMRRMEHHGPSASVMEEENARLLGILKTVQD 2544 Query: 802 LGSYLQEKQKAY-SEYTIQEDELVN---RLAVLMDH--DRVVEKQLLEIEHENKELQKKN 855 LQ + K +E + +D+ ++ ++A+L D R E +L ++ + + Q Sbjct: 2545 ESKKLQSRIKMLENELNLVKDDAMHKGEKVAILQDKLLSRNAEAELNAMQVKLTKKQDNL 2604 Query: 856 QILLEENQNLQISLSDMQQHYNALVEK-ANRTDLAESESTKYQTQLRDLESNLKRITHEH 914 Q ++E +NLQ ++ Y ++ + E E KY + LK + Sbjct: 2605 QAAMKEIENLQKMVAKGAVPYKEEIDNLKTKVVKIEMEKIKYSKATDQEIAYLKSCLEDK 2664 Query: 915 QTLIVQKKKEIEDLEIEFNTQI 936 + + + K+E+ + + +T + Sbjct: 2665 EEGLRRLKEELRRAQADNDTTV 2686 Score = 58.4 bits (135), Expect = 2e-06 Identities = 178/931 (19%), Positives = 359/931 (38%), Gaps = 89/931 (9%) Query: 664 LEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDK 723 L++Q++ L +S + A + K + QL IK L ++ED + L N + + + + Sbjct: 356 LKKQLENLESSSETKAQAMA--KEEHTQLLAEIKQLHKEREDRIWHLTNIVVASSQESQQ 413 Query: 724 LEKMSAEK-ISELLAKINH----------EEQSKIQTQFGIDAKIQERDLYIENIESELS 772 +++ ++ ++ KI + + S++ F AK + + E +S + Sbjct: 414 DQRVKRKRRVTWAPGKIQNSLHASGVSDFDMLSRLPGNFSKKAKFSDMPSFPEIDDSVCT 473 Query: 773 KYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMD 832 ++ ++++++M+ E L S + ++K ++ + ++ Sbjct: 474 EFSD----FDDALSMMDSNGIDAEWN---LASKVTHREKTSLHQSMIDFGQISDSVQF-- 524 Query: 833 HDRVVEKQLLEIEHENKELQKKNQILLE-ENQNLQISLSDMQQHYNALVE--KANRTDLA 889 HD E QL + ++ ++ + + E E +LQ L ++ LV+ + +L Sbjct: 525 HDSSKENQLQYLPKDSGDMAECRKASFEKEITSLQQQLQSKEEEKKELVQSFELKIAELE 584 Query: 890 ESESTKYQTQLRDLESNLKRITHEHQTLIVQK--KKEIEDLEIE----FNTQIESAIRDK 943 E S K + S I E QT + ++ +KE+ L N+ ++ + D Sbjct: 585 EQLSVKAKNLEMVTNSREHSINAEVQTDVEKEVVRKEMSVLGDSGYNASNSDLQDSSVDG 644 Query: 944 KVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDY 1003 K L+ +++ IE+ LE ++ + + IENLN E + + E ++ Q Sbjct: 645 KRLSSSHDECIEHRKMLEQKIVDLEEFIENLNKKSENDKQKSSE--QDFMESIQLCEAIM 702 Query: 1004 TEQYINEINKLNALLKQKDEEIIALNQKINNAQVSY-MSMVSDYESKLAQFTTKLENMEE 1062 E+ N + +L AL++ + II N+ + S+ + E+ + K E Sbjct: 703 AEK-ANALEEL-ALMRDNFDNIILENETLKREIADLERSLKENQETNEFEILEKETQKEH 760 Query: 1063 EMQRVSK-QLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPM 1121 E Q + + L N E+ E+D + K TKL E I E + + + Sbjct: 761 EAQLIHEIGSLKKLVENAEMYNQNLEEDLETK----TKLLKEQEIQLAE---LRKRADNL 813 Query: 1122 SDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETL 1181 N D EE Q + L + A +EC ++ E L Sbjct: 814 QKKVRNFDLSVSMGDSEKLC------EEIFQLKQSLSDAEAVTRDAQKEC--SFLRSENL 865 Query: 1182 NTELTGHDVVNQEQINQLKSKL--EQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELW 1239 + D N + + L +QL TE N A+L+ + SA ++ + Sbjct: 866 ELKEKMEDTSNWYNQKEKAASLFEKQLETEKSNYKKMEADLQKELQSAFNEINY-----L 920 Query: 1240 KQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEET---NKIVTMEQVTSLQ 1296 LA + + EL ++S F + E+ L+ + E T +V L+ Sbjct: 921 NGLLAGKVPRDLLSRVELEKKVSEFSKQLEKALEEKNALENEVTCLSEYKFLPNEVECLK 980 Query: 1297 NKLQDKEEHLRNLQ---EKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLR 1353 N++ E + L+ E A +I++ EI+ E ++ + Sbjct: 981 NQISKASEEIMLLKQEGEHSASIISKQEIIMQEQSEQILQLTDEVTHTQSKVQQTEEQYL 1040 Query: 1354 TENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLE--L 1411 + + + E+ I N +E L++ + E K+ + H+LE + Sbjct: 1041 EMKKMHDDLFEKYIRNKSEAEDLLREMENLKGT--------MESVEVKIADTKHELEETI 1092 Query: 1412 KDSE--IYQKTHEY----TI-TLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRL 1464 +D E +++K + + TI +T +D + + IE Y LA R Sbjct: 1093 RDKEQLLHEKKYFFQAMQTIFPITPLSDSLPPSKLVEGNSQDPIEINDYHNLIALATERN 1152 Query: 1465 KMHENANHYETMQKESEIERVKLIEELNVKITESVSLNK-----QVAELNKALEEEVAK- 1518 + KE I+ ++ L + E L K + E+ LE E+ K Sbjct: 1153 NIMVCLETERNSLKEQVIDLNTQLQSLQAQSIEKSDLQKPKQDLEEGEVKLLLEMELLKG 1212 Query: 1519 -TNEMQTALENQEIEIVTLNDEITNLQNMVR 1548 + Q ++E ++E + + +++ LQ ++ Sbjct: 1213 HLTDSQLSIEKLQLENLEVTEKLQTLQEEMK 1243 Score = 45.2 bits (102), Expect = 0.015 Identities = 78/357 (21%), Positives = 160/357 (44%), Gaps = 36/357 (10%) Query: 465 LIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANK 524 L VG+ ++ E K Q +E D V+ K L E ++ +I + K Sbjct: 2425 LNQVGSTLQEELEHKKGFMQWLEEFGD--LHVDAKKLSEGMQQENRRIASTIQLLTKRLK 2482 Query: 525 NMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLH 584 +++ K ++ + + + + + NKE++R E H S V E EE L + Sbjct: 2483 AVVQSKIQREITV-YLNQFEAKLQEKKEQNKELMRRMEH-HGPSASVME-EENARLLGIL 2539 Query: 585 LVDYDSGRMIESDVYKKMIEME-NLAET----RLKAISLLESQKF--DLVQELHILQQKY 637 D + ++S + KM+E E NL + + + +++L+ + + EL+ +Q K Sbjct: 2540 KTVQDESKKLQSRI--KMLENELNLVKDDAMHKGEKVAILQDKLLSRNAEAELNAMQVKL 2597 Query: 638 DEVEDKL-ADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDK--EQLYG 694 + +D L A + ++++ Q +V +E+ID L K + + +E +K K +Q Sbjct: 2598 TKKQDNLQAAMKEIENLQKMVAKGAVPYKEEIDNLKT--KVVKIEMEKIKYSKATDQEIA 2655 Query: 695 TIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGID 754 +K DKE+ + +L+ ++L + A+ + + ++++ S G Sbjct: 2656 YLKSCLEDKEEGLRRLK----------EELRRAQADNDTTVCVPKDYQKASTFPVTCGGG 2705 Query: 755 AKIQERD--LYIEN----IESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSY 805 + I + L +++ +E ELS YK + L +++ EDR+ + K+D S+ Sbjct: 2706 SGIVQSTAMLVLQSEKAALERELSHYKKKYHHLSRTMSSSEDRK-KTKAKSDAHSSH 2761 >UniRef50_A2D7K4 Cluster: Putative uncharacterized protein; n=1; Trichomonas vaginalis G3|Rep: Putative uncharacterized protein - Trichomonas vaginalis G3 Length = 994 Score = 125 bits (302), Expect = 9e-27 Identities = 192/1000 (19%), Positives = 424/1000 (42%), Gaps = 58/1000 (5%) Query: 596 SDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQV 655 +D K + E+ K + L ++ D E+ ++ +Y+E D+ SQ + +Q Sbjct: 2 NDNEKWLYEINKKIAALTKIVFQLHTEATDRKDEVARMKVRYEEELDQAFKASQDRIEQA 61 Query: 656 CSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQ 715 E+++ + A + E + + +QL K + ++ +N+L+ ++ Sbjct: 62 QKEVQNYKQSIEKTVRQAYESEFNKIKKLYDQANDQLNSKSKSIIDNSNKRLNQLKKEVE 121 Query: 716 ENMDLTDKLEKMSA--EKISELLAKINHEEQSKIQTQFGID--AKIQERDLYIENIESEL 771 DL K + SA + S+ L KI + +KI+ + D ++ E + + Sbjct: 122 ---DLKKKADSQSALFDNASKELEKIAADTVAKIEDKHKKDLAKRVTEANKKYNQLVVAT 178 Query: 772 SKYKSRI-CRLEESIAVMEDRRYSLER-KADQLGSYLQEKQKAYSEYTIQEDEL---VNR 826 SK + + R E+ + ++++ + ++ +++ L S ++ I D + V+ Sbjct: 179 SKKEEELKARFEKELQDLKNQLAAGQKNQSEMLSSKQKDIDSKIKRLEITRDLVQRGVDE 238 Query: 827 LAVLMD-HDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANR 885 L L++ + VE +L +I+ + + L +++I L E L+ + + Q +++ E A Sbjct: 239 LKQLLETQKKQVEDKLKQIQEQRQRLANQSEIELHE---LKHKMKESQNNHDQ--EMAKI 293 Query: 886 TDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRD-KK 944 + + ++ + DL+S +++ EH+ + + +K+ ++ + + + ++ K+ Sbjct: 294 QSMIDQAQADHEKAVNDLKSQVEKAKLEHEQKLQELQKQSKNSAEDGEQKKKKLLQQHKQ 353 Query: 945 VLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYT 1004 +++ K+ ++V++ E + QE + +E+L E K I+K + Sbjct: 354 AMDDLKAKHAQFVSESEKREQELQKQLEDLQRKHESSMKKIRGDIEKEKKSHADNMAMLD 413 Query: 1005 EQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEM 1064 Q+ E+ + L ++ ++E++ L ++ NA ++ S L ++E + EE+ Sbjct: 414 TQHQQELQR---LAEEHEKEMMKLKKEYENAS-------NNSNSSLKDILDEIERVREEI 463 Query: 1065 QRVSKQLLDS--KQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMS 1122 ++ K+ D ++ E ++ + + D K + E K E + K + + E Sbjct: 464 KKKIKEGEDEIIRKQKERQEMEEKLKSDHEKRMSEIKQNHEERMKKLDEETQAKIDEMNR 523 Query: 1123 DDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSV-LQEQSAKLNTELQECYTKIIQLETL 1181 N+ + E +R + L E A ++ E KI E+ Sbjct: 524 KHQENMKRIETEAQEKLSRDSAALKNELESQRQIQLSELKATWKKKINEIKQKI---ESR 580 Query: 1182 NTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQ 1241 + QE+ + ++K+EQL E + L AE + I+ ++ + +L K+ Sbjct: 581 QKAKADAEHFLQEETAKRQAKIEQLRQELETLKKNWAEEKEKINKEYSEK---LEKLKKE 637 Query: 1242 HLAQREADFQKTEHELRVQLSAFESKYEQLLDSV--QSSTQEETNKIVTMEQVTSLQNKL 1299 + EA+ +K E + R++ +++Y++ +D + Q + +EE K + + +Q K Sbjct: 638 N---EEAE-RKAEEQRRLK----DAEYQKAIDDLKKQLNDEEEKKKKIISDLEQKIQQKE 689 Query: 1300 QDKEEHLRNLQEKYADVI--NQIEI--LRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTE 1355 ++ EE L+ E+ + Q EI L +I D K L+ E Sbjct: 690 KENEEELKRQNEEIEKLTQKRQTEIHELELKINDLKAETNKKVQEIDEEKKKELSKLQQE 749 Query: 1356 NQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXR-VNDAEAKVLELTHQLELKDS 1414 K+ EQ I + ++ Q+KK + DA ++ + + E S Sbjct: 750 YDEIKKKGEQEIERLQKQLDQIKKEHEQQLNEIKAKIAKEEEDARQRLDAMKQENERILS 809 Query: 1415 EIYQKTHEYTITLTQRNDEFENVRQQLV-EYEKRIEDLTYEKESELAILRLKMHENANHY 1473 EI QK + L + + ++ +L ++ +R+ + E++L IL+ K Sbjct: 810 EIKQKHKKEMDVLNEELRKLQDEECELERKHNERLAQQQRDYENKLDILKKKYDAEKEKI 869 Query: 1474 ETMQKESEIERVKLIEEL--NVKITESVSLNKQV-AELNKALEEEVAKTNEMQTALENQE 1530 T + E E+ + I EL + E N++ E + +++ A E A+E + Sbjct: 870 TTEIAKIEQEKKQRIAELEEETRTWEDRYNNREARPEDLEKIQKLEALIAERSAAIEKVQ 929 Query: 1531 IEIVTLNDEITNLQNMV-RASSSKIQKHVSFASDTKQGRD 1569 E+ E+ N + + ++K Q +V A + K RD Sbjct: 930 SELKRYQAELLNRETTYNKVFNNKPQVNVLSALERKARRD 969 Score = 121 bits (291), Expect = 2e-25 Identities = 202/952 (21%), Positives = 438/952 (46%), Gaps = 111/952 (11%) Query: 401 KINKNEIAKLEMVIQSLNKDLVD-KEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQH 459 +INK +IA L ++ L+ + D K+ V K I Q Q E Q + Sbjct: 10 EINK-KIAALTKIVFQLHTEATDRKDEVARMKVRYEEELDQAFKASQDRIEQAQKEVQNY 68 Query: 460 MEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDV--NVKDLIEKLKSAEEQITQLND 517 + + N+I K+ +Q +LN + K + N + +LK E + + D Sbjct: 69 KQSIEKTVRQAYESEFNKIKKLYDQANDQLNSKSKSIIDNSNKRLNQLKKEVEDLKKKAD 128 Query: 518 E----IDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKV-A 572 D A+K + K+ ++ K++ K D +V+++NK+ +L +++ A Sbjct: 129 SQSALFDNASKELEKIAADTVAKIEDKHKK-DLAKRVTEANKKYNQLVVATSKKEEELKA 187 Query: 573 ELEEEKGNL--QLHLVDYDSGRMIES---DVYKKMIEMENLAETRLKAIS----LLESQK 623 E+E +L QL + M+ S D+ K+ +E + + + LLE+QK Sbjct: 188 RFEKELQDLKNQLAAGQKNQSEMLSSKQKDIDSKIKRLEITRDLVQRGVDELKQLLETQK 247 Query: 624 FDLVQELHILQQKYDEV----EDKLADI------SQLQSDQVCSEIKSVHLEEQIDALSA 673 + +L +Q++ + E +L ++ SQ DQ ++I+S+ + Q D A Sbjct: 248 KQVEDKLKQIQEQRQRLANQSEIELHELKHKMKESQNNHDQEMAKIQSMIDQAQADHEKA 307 Query: 674 SKKELALVIENLKLDKEQ-LYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKI 732 +L +E KL+ EQ L K +N ED K + +Q++ D L+ A+ + Sbjct: 308 VN-DLKSQVEKAKLEHEQKLQELQKQSKNSAEDGEQKKKKLLQQHKQAMDDLKAKHAQFV 366 Query: 733 SELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDR- 791 SE + + + ++Q Q ++ ++ + ++ I ++ K K +++A+++ + Sbjct: 367 SE-----SEKREQELQKQ--LEDLQRKHESSMKKIRGDIEKEKKSHA---DNMAMLDTQH 416 Query: 792 RYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDH-DRV---VEKQLLEIEHE 847 + L+R A++ + +E K EY + + L ++D +RV ++K++ E E E Sbjct: 417 QQELQRLAEE---HEKEMMKLKKEYENASNNSNSSLKDILDEIERVREEIKKKIKEGEDE 473 Query: 848 NKELQKKNQILLEE-NQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESN 906 QK+ Q + E+ + + +S+++Q++ ++K L E K R + N Sbjct: 474 IIRKQKERQEMEEKLKSDHEKRMSEIKQNHEERMKK-----LDEETQAKIDEMNRKHQEN 528 Query: 907 LKRITHEHQTLIVQKKKEIEDLEIEFNTQIE-SAIRD--KKVLNEKYEKNIEYVTQLEAQ 963 +KRI E Q + + +++ E+E QI+ S ++ KK +NE +K IE + +A Sbjct: 529 MKRIETEAQEKLSRDSAALKN-ELESQRQIQLSELKATWKKKINEIKQK-IESRQKAKAD 586 Query: 964 LQEY-KNNIENLNMNVEELNKMNLELIDKH-VQKQQTQSPDYTEQYINEINKLNALLKQK 1021 + + + +E+L + LE + K+ ++++ + +Y+E+ + ++ K N ++K Sbjct: 587 AEHFLQEETAKRQAKIEQL-RQELETLKKNWAEEKEKINKEYSEK-LEKLKKENEEAERK 644 Query: 1022 DEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEEL 1081 EE +++ +A+ Y + D + +L K + + ++++ +Q K++ EEL Sbjct: 645 AEE----QRRLKDAE--YQKAIDDLKKQLNDEEEKKKKIISDLEQKIQQ--KEKENEEEL 696 Query: 1082 QILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXX 1141 + Q+++I++L + + +TE + I + + N Sbjct: 697 ----KRQNEEIEKLTQKR--------QTEIHELELKINDLKAETNK-------------- 730 Query: 1142 LKVQE-EEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLK 1200 KVQE +EE +E S LQ++ ++ + ++ ++E L +L +++Q+N++K Sbjct: 731 -KVQEIDEEKKKELSKLQQEYDEIKKKGEQ------EIERLQKQLDQIKKEHEQQLNEIK 783 Query: 1201 SKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQ 1260 +K+ + + L + + I S + Q+ + ++ + L + + + + E + + Sbjct: 784 AKIAKEEEDARQRLDAMKQENERILSEIKQKHKKEMDVLNEELRKLQDEECELERKHNER 843 Query: 1261 LSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEK 1312 L+ + YE LD ++ E KI T ++ ++ Q+K++ + L+E+ Sbjct: 844 LAQQQRDYENKLDILKKKYDAEKEKITT--EIAKIE---QEKKQRIAELEEE 890 Score = 50.0 bits (114), Expect = 5e-04 Identities = 90/459 (19%), Positives = 185/459 (40%), Gaps = 34/459 (7%) Query: 154 KDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXED 213 K+ S Q+++ ++ T ++KINE Q IE++ KA E Sbjct: 548 KNELESQRQIQLSELKAT---WKKKINEIKQKIESRQKAKADAEHFLQEETAKRQAKIEQ 604 Query: 214 TKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRI-SSLEEANKLLEAARFEISLEHS 272 +Q++ +++N W +EK+++ K+ K ++ EEA + E R E+ Sbjct: 605 LRQELETLKKN-------WAEEKEKINKEYSEKLEKLKKENEEAERKAEEQRRLKDAEYQ 657 Query: 273 KLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLE 332 K +L++ +Q I+ +E E ++ + EI +T+ K+ + Sbjct: 658 KAIDDLKKQLNDEEEKKKKIISDLEQKIQQKEKENEEELKRQNEEIEKLTQ--KRQTEIH 715 Query: 333 HLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSE 392 L +I E K+ + E K S ++ I +K G +++ Q+ E Sbjct: 716 ELELKINDLKAETNKKVQEIDEEKKKELSKLQQEYDEI-KKKGEQEIERLQKQLDQIKKE 774 Query: 393 ---TLNQDTDKKINKNEIAKL---------EMVIQSLNKDLVDKEYVISEKDTXXXXXXX 440 LN+ K + E A+ E ++ + + + V++E+ Sbjct: 775 HEQQLNEIKAKIAKEEEDARQRLDAMKQENERILSEIKQKHKKEMDVLNEELRKLQDEEC 834 Query: 441 XXXGK-DTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQ---ELNDEIKDV 496 K + +AQ Q +++ ++ + + EIAK++++ KQ EL +E + Sbjct: 835 ELERKHNERLAQQQRDYENKLDILKKKYDAEKEKITTEIAKIEQEKKQRIAELEEETRTW 894 Query: 497 NVKDLIEKLKSAE-EQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNK 555 + + + + E+I +L I + + KV+S K ++ ++KV +NK Sbjct: 895 EDRYNNREARPEDLEKIQKLEALIAERSAAIEKVQSELKRYQAELLNRETTYNKVF-NNK 953 Query: 556 EIVRLTEELHHLSQKVAELEEEKGNLQLHLV--DYDSGR 592 V + L +++ A + +L V +DS R Sbjct: 954 PQVNVLSALERKARRDAIIAAANSTSKLPPVKDSHDSAR 992 >UniRef50_Q4D6G7 Cluster: Putative uncharacterized protein; n=4; Trypanosoma cruzi|Rep: Putative uncharacterized protein - Trypanosoma cruzi Length = 2493 Score = 125 bits (301), Expect = 1e-26 Identities = 249/1481 (16%), Positives = 586/1481 (39%), Gaps = 105/1481 (7%) Query: 144 VTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXX 203 V L ++E+D+AL+ L +++ L+ + +E + A + Sbjct: 699 VVTLRRQLQERDDALAALNDRLEEHSREKSALESRTSESVDALAAMERQLQERDDALAAL 758 Query: 204 XXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAA 263 +D ++ ++ + + +E D + + ++ +D +++L++ +L E Sbjct: 759 --------KDRLEEHSREKSALESRTSESVDALAAMERQLQERDDALAALKD--RLEEYG 808 Query: 264 RFEISLEHSKLAQELEQXXXXXXXXXXXXXXLA--KQSIEPSCEEKTEIEEKGSLEIANM 321 R + +LE S+ ++ ++ LA K +E EK+ +E + S + + Sbjct: 809 REKSALE-SRTSESVDAVVTLSRQLQERDDALAALKDRLEEHSREKSALESRTSESVDAL 867 Query: 322 TELTKKIELLEHLNCQIRQTNKEL-ENKLATMGTESKAVSSP-------SKKGSPLISRK 373 + ++++ + ++ +E K A S++V + ++ L + Sbjct: 868 AAMERQLQERDDALAALKDRLEEYGREKSALESRTSESVDAVVTLRRQLQERDDALAALN 927 Query: 374 SGRNTASKMKSPWSQLSSETLN----QDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVIS 429 S+ KS +SE+++ + + + +A L+ ++ +++ E S Sbjct: 928 DRLEEHSREKSALESRTSESVDALAAMERQPQERDDALAALKDRLEEYSREKSALESRTS 987 Query: 430 EKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQE- 488 E +D +A L+ +++ S + T+ E V+ +A ++ QL++ Sbjct: 988 ESVDAVVTLRRQLQERDDALAALKDRLEEYSREKSALESRTS-ESVDALAAMERQLQERD 1046 Query: 489 -----LNDEIKDVN-VKDLIEKLKS-------AEEQITQLNDEIDAANKNMIKVKSNHKL 535 LND +++ + K +E S A E+ Q D+ AA K+ ++ S K Sbjct: 1047 DALAALNDRLEEYSREKSALESRTSESVDALAAMERRLQERDDALAALKDRLEEYSREKS 1106 Query: 536 KLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVD-YDSGRMI 594 L+ +T ++ ++ +++ + L L+ ++ E EK L+ + D+ + Sbjct: 1107 ALES--RTSESVGALAAMERQLQERDDALAALNDRLEEYGREKSALESRTSESVDAVVTL 1164 Query: 595 ESDVYKK---MIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADIS-QL 650 + ++ + +++ E + S LES+ + V L ++++ E +D LA ++ +L Sbjct: 1165 RRQLQERDDALAALKDRLEEHSREKSALESRTSESVDALAAMERQLQERDDALAALNDRL 1224 Query: 651 QSDQVCSEIKSVHLEEQIDALSASKKEL-----ALVIENLKLDK-EQLYGTIKDLENDKE 704 + E +DAL+A +++ AL N +L++ + ++ ++ Sbjct: 1225 EEHSREKSALESRTSESVDALAAMERQPQERDDALAALNDRLEEYSREKSALESRTSESV 1284 Query: 705 DIMNKLQNYIQENMD----LTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQER 760 D + L+ +QE D L D+LE+ S EK + + + + ++QER Sbjct: 1285 DAVVTLRRQLQERDDALAALKDRLEEHSREK-----SALESRTSESVDAVVTLRRQLQER 1339 Query: 761 DLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQE 820 D + ++ L +Y LE + ++ER+ + L EY ++ Sbjct: 1340 DDALAALKDRLEEYSREKSALESRTSESVGALAAMERQLQERDDALAALNDRLEEYGREK 1399 Query: 821 DELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALV 880 L +R + +D + +QL E + L+ + + E L+ S+ A+ Sbjct: 1400 SALESRTSESVDAVVTLRRQLQERDDALAALKDRLEEYGREKSALESRTSESVDALAAME 1459 Query: 881 EKAN-RTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKK--EIEDLEIEFNTQIE 937 + R D + + + R+ + R + L +++ E +D N ++E Sbjct: 1460 RQLQERDDALAALKDRLEEHSREKSALESRTSESVDALAAMERQLQERDDALAALNDRLE 1519 Query: 938 SAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQ 997 R+K L + ++++ + +E QLQE + + L +EE ++ +K Sbjct: 1520 EHSREKSALESRTSESVDALAAMERQLQERDDALAALKDRLEEYSR----------EKSA 1569 Query: 998 TQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKL 1057 +S T + ++ + L L+++D+ + AL ++ Y S ES+ ++ L Sbjct: 1570 LESR--TSESVDAVVTLRRQLQERDDALAALKDRLEE----YSREKSALESRTSESVGAL 1623 Query: 1058 ENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISST 1117 ME ++Q L EE + + E + +T + + + + + Sbjct: 1624 AAMERQLQERDDALAALNDRLEEYDREKSALESRTSESVDAVVTLRRQLQERDDALAALN 1683 Query: 1118 IEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQ 1177 + + + L E + +QER + A L L+E + Sbjct: 1684 -DRLEEYGREKSALESRTSGSVDALAAMERQ--LQERD---DALAALKDRLEEYGREKSA 1737 Query: 1178 LETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAE 1237 LE+ +E V + Q+ + L LN + + L S S +VD + Sbjct: 1738 LESRTSESVDAVVTLRRQLQERDDALAALNDRLEEYGREKSALESRTSESVDALAAMERQ 1797 Query: 1238 LWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQN 1297 L ++ A + EH + S ES+ + +D++ + ++ + + + +L++ Sbjct: 1798 LQERDDALAALKDRLEEHSR--EKSVLESRTSESVDALAAMERQLQERD---DALAALKD 1852 Query: 1298 KLQDKEEHLRNLQEKYADVINQIEILRSEIE--DEKVAFXXXXXXXXXXXXXXXXDLRTE 1355 +L++ L+ + ++ ++ + LR +++ D+ +A +E Sbjct: 1853 RLEEHSREKSALESRTSESVDAVVTLRRQLQERDDALAALKDRLEEYGREKSALESRTSE 1912 Query: 1356 NQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKD-- 1413 + + + ++ A LK R +++ + + QL+ +D Sbjct: 1913 SVDAVVTLRRQLQERDDALAALKDRLEEYSREKSALESRTSESVDALAAMERQLQERDDA 1972 Query: 1414 -SEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANH 1472 + + K EY + E+ + V+ + E++ LA L ++ E++ Sbjct: 1973 LAALKDKLEEYG----REKSALESRTSESVDAVVTLRRQLQERDDALAALNDRLEEHSRE 2028 Query: 1473 YETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIE 1532 ++ + E V + + ++ E + +A LN LEE + + +++ Sbjct: 2029 KSALESRTS-ESVDALAAMERQLQER---DDALAALNDKLEEYGREKSALESRTSESVDA 2084 Query: 1533 IVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLD 1573 +VTL ++ + + A + ++++H S + E +D Sbjct: 2085 VVTLRRQLQERDDALAALNDRLEEHSREKSALESRTSESVD 2125 Score = 115 bits (276), Expect = 1e-23 Identities = 274/1508 (18%), Positives = 599/1508 (39%), Gaps = 123/1508 (8%) Query: 147 LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXX 206 L++ ++E SVL+ + ++ L+ ++ E+D + A Sbjct: 576 LNDKLEEYGREKSVLESRTSESVDVVVTLERQLQERDDALAALKDRLEEHSREKSVLESR 635 Query: 207 XXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFE 266 + ++QE+ A+ A + + ++ +D +++L++ +L E R + Sbjct: 636 TSESVDVVVTLERQLQESVDALAA--------MERQLQERDDALAALKD--RLEEYGREK 685 Query: 267 ISLEHSKLAQELEQXXXXXXXXXXXXXXLA--KQSIEPSCEEKTEIEEKGSLEI----AN 320 +LE S+ ++ ++ LA +E EK+ +E + S + A Sbjct: 686 SALE-SRTSESVDAVVTLRRQLQERDDALAALNDRLEEHSREKSALESRTSESVDALAAM 744 Query: 321 MTELTKKIELLEHLNCQIRQTNKE---LENKLATMGTESKAVSSP-SKKGSPLISRKSGR 376 +L ++ + L L ++ + ++E LE++ + A+ ++ L + K Sbjct: 745 ERQLQERDDALAALKDRLEEHSREKSALESRTSESVDALAAMERQLQERDDALAALKDRL 804 Query: 377 NTASKMKSPWSQLSSETLNQ--DTDKKINKNE--IAKLEMVIQSLNKDLVDKEYVISEKD 432 + KS +SE+++ +++ + + +A L+ ++ +++ E SE Sbjct: 805 EEYGREKSALESRTSESVDAVVTLSRQLQERDDALAALKDRLEEHSREKSALESRTSESV 864 Query: 433 TXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQE---- 488 +D +A L+ +++ S + T +E V+ + ++ QL++ Sbjct: 865 DALAAMERQLQERDDALAALKDRLEEYGREKSALESRT-SESVDAVVTLRRQLQERDDAL 923 Query: 489 --LNDEIKD-VNVKDLIEKLKS-------AEEQITQLNDEIDAANKNMIKVKSNHKLKLK 538 LND +++ K +E S A E+ Q D+ AA K+ ++ S K L+ Sbjct: 924 AALNDRLEEHSREKSALESRTSESVDALAAMERQPQERDDALAALKDRLEEYSREKSALE 983 Query: 539 QMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVD-YDSGRMIESD 597 +T ++ V +++ + L L ++ E EK L+ + D+ +E Sbjct: 984 --SRTSESVDAVVTLRRQLQERDDALAALKDRLEEYSREKSALESRTSESVDALAAMERQ 1041 Query: 598 VYKK---MIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADI-SQLQSD 653 + ++ + + + E + S LES+ + V L ++++ E +D LA + +L+ Sbjct: 1042 LQERDDALAALNDRLEEYSREKSALESRTSESVDALAAMERRLQERDDALAALKDRLEEY 1101 Query: 654 QVCSEIKSVHLEEQIDALSASKKELALVIENLKL--DKEQLYGTIKD-LE---NDKEDIM 707 E + AL+A +++L + L D+ + YG K LE ++ D + Sbjct: 1102 SREKSALESRTSESVGALAAMERQLQERDDALAALNDRLEEYGREKSALESRTSESVDAV 1161 Query: 708 NKLQNYIQENMD----LTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLY 763 L+ +QE D L D+LE+ S EK + + + ++ ++QERD Sbjct: 1162 VTLRRQLQERDDALAALKDRLEEHSREK-----SALESRTSESVDALAAMERQLQERDDA 1216 Query: 764 IENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDEL 823 + + L ++ LE + D ++ER+ + L EY+ ++ L Sbjct: 1217 LAALNDRLEEHSREKSALESRTSESVDALAAMERQPQERDDALAALNDRLEEYSREKSAL 1276 Query: 824 VNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEK- 882 +R + +D + +QL E + L+ + + E L+ S+ L + Sbjct: 1277 ESRTSESVDAVVTLRRQLQERDDALAALKDRLEEHSREKSALESRTSESVDAVVTLRRQL 1336 Query: 883 ANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKK--KEIEDLEIEFNTQIESAI 940 R D + + + R+ + R + L ++ +E +D N ++E Sbjct: 1337 QERDDALAALKDRLEEYSREKSALESRTSESVGALAAMERQLQERDDALAALNDRLEEYG 1396 Query: 941 RDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQS 1000 R+K L + ++++ V L QLQE + + L +EE + L + + + Sbjct: 1397 REKSALESRTSESVDAVVTLRRQLQERDDALAALKDRLEEYGREKSALESR--TSESVDA 1454 Query: 1001 PDYTEQYINEINKLNALLKQKDE----EIIALNQKINNAQVSYMSM---VSDYESKLAQF 1053 E+ + E + A LK + E E AL + + + + +M + + + LA Sbjct: 1455 LAAMERQLQERDDALAALKDRLEEHSREKSALESRTSESVDALAAMERQLQERDDALAAL 1514 Query: 1054 TTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMI 1113 +LE E + + +S ++ ++E+DD + LK+ + + + + Sbjct: 1515 NDRLEEHSREKSALESRTSESVDALAAMERQLQERDDALAALKDRLEEYS----REKSAL 1570 Query: 1114 ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQS-------AKLNT 1166 S T E + D + LK EE+ +E+S L+ ++ A + Sbjct: 1571 ESRTSESV-DAVVTLRRQLQERDDALAALK-DRLEEYSREKSALESRTSESVGALAAMER 1628 Query: 1167 ELQECYTKII----QLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNL--LSTVAEL 1220 +LQE + +LE + E + + E ++ + + QL +D L L+ E Sbjct: 1629 QLQERDDALAALNDRLEEYDREKSALESRTSESVDAVVTLRRQLQERDDALAALNDRLEE 1688 Query: 1221 RSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQ 1280 SA++ R + LA E Q+ + L E +Y + +++S T Sbjct: 1689 YGREKSALESRTSGSVDA----LAAMERQLQERDDALAALKDRLE-EYGREKSALESRTS 1743 Query: 1281 EETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIED--EKVAFXXXX 1338 E + +VT L+ +LQ++++ L L ++ + + L S + + +A Sbjct: 1744 ESVDAVVT------LRRQLQERDDALAALNDRLEEYGREKSALESRTSESVDALAAMERQ 1797 Query: 1339 XXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDA 1398 D E+ K + E + A +++ R+ + Sbjct: 1798 LQERDDALAALKDRLEEHSREKSVLESRTSESVDALAAMERQLQERDDALAALKDRLEEH 1857 Query: 1399 EAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEY---EKRIEDLTYEK 1455 + LE + SE L +R+D ++ +L EY + +E T E Sbjct: 1858 SRE----KSALESRTSESVDAVVTLRRQLQERDDALAALKDRLEEYGREKSALESRTSES 1913 Query: 1456 ESELAILRLKMHENANHYETMQ---KESEIERVKLIEELNVKITESVSLNKQVAELN--- 1509 + LR ++ E + ++ +E E+ L + + ++ +Q+ E + Sbjct: 1914 VDAVVTLRRQLQERDDALAALKDRLEEYSREKSALESRTSESVDALAAMERQLQERDDAL 1973 Query: 1510 KALEEEVAKTNEMQTALENQEIE----IVTLNDEITNLQNMVRASSSKIQKHVSFASDTK 1565 AL++++ + ++ALE++ E +VTL ++ + + A + ++++H S + Sbjct: 1974 AALKDKLEEYGREKSALESRTSESVDAVVTLRRQLQERDDALAALNDRLEEHSREKSALE 2033 Query: 1566 QGRDEQLD 1573 E +D Sbjct: 2034 SRTSESVD 2041 Score = 114 bits (274), Expect = 2e-23 Identities = 236/1332 (17%), Positives = 527/1332 (39%), Gaps = 104/1332 (7%) Query: 298 QSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESK 357 Q I + EEK +++++ + I ++ + +L + L+ +I +E N+ A T K Sbjct: 464 QQIRKNAEEKLQLQQR--ILINTRSKNMGETQLRQKLSQEIDTKEREDNNRNAKTFTRIK 521 Query: 358 AVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNE--IAKLEMVIQ 415 + +P + R+ + K + + ++++ + + +A L ++ Sbjct: 522 HFYTQDSPRTPPVQRRLDFSGKEKHLLKDCPIKGFDVLATLERQLQERDDALAALNDKLE 581 Query: 416 SLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDV 475 ++ E SE +D +A L+ ++H S++ T+ E V Sbjct: 582 EYGREKSVLESRTSESVDVVVTLERQLQERDDALAALKDRLEEHSREKSVLESRTS-ESV 640 Query: 476 NEIAKVQEQLKQELN---------DEIKDV--NVKDLIEKL---KSAEEQIT-------- 513 + + ++ QL++ ++ E D +KD +E+ KSA E T Sbjct: 641 DVVVTLERQLQESVDALAAMERQLQERDDALAALKDRLEEYGREKSALESRTSESVDAVV 700 Query: 514 ----QLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQ 569 QL + DA +++ + + K +T ++ ++ +++ + L L Sbjct: 701 TLRRQLQERDDALAALNDRLEEHSREKSALESRTSESVDALAAMERQLQERDDALAALKD 760 Query: 570 KVAELEEEKGNLQLHLVD-YDSGRMIESDVYKK---MIEMENLAETRLKAISLLESQKFD 625 ++ E EK L+ + D+ +E + ++ + +++ E + S LES+ + Sbjct: 761 RLEEHSREKSALESRTSESVDALAAMERQLQERDDALAALKDRLEEYGREKSALESRTSE 820 Query: 626 LVQELHILQQKYDEVEDKLADIS-QLQSDQVCSEIKSVHLEEQIDALSASKKELALVIEN 684 V + L ++ E +D LA + +L+ E +DAL+A +++L + Sbjct: 821 SVDAVVTLSRQLQERDDALAALKDRLEEHSREKSALESRTSESVDALAAMERQLQERDDA 880 Query: 685 LKLDKEQL--YGTIKD-LEN---DKEDIMNKLQNYIQENMD----LTDKLEKMSAEKISE 734 L K++L YG K LE+ + D + L+ +QE D L D+LE+ S EK Sbjct: 881 LAALKDRLEEYGREKSALESRTSESVDAVVTLRRQLQERDDALAALNDRLEEHSREK--- 937 Query: 735 LLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYS 794 + + + ++ + QERD + ++ L +Y LE + D + Sbjct: 938 --SALESRTSESVDALAAMERQPQERDDALAALKDRLEEYSREKSALESRTSESVDAVVT 995 Query: 795 LERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKK 854 L R+ + L + EY+ ++ L +R + +D +E+QL E + L + Sbjct: 996 LRRQLQERDDALAALKDRLEEYSREKSALESRTSESVDALAAMERQLQERDDALAALNDR 1055 Query: 855 NQILLEENQNLQISLSDMQQHYNALVEK-ANRTDLAESESTKYQTQLRDLESNLKRITHE 913 + E L+ S+ A+ + R D + + + R+ + R + Sbjct: 1056 LEEYSREKSALESRTSESVDALAAMERRLQERDDALAALKDRLEEYSREKSALESRTSES 1115 Query: 914 HQTLIVQKK--KEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNI 971 L ++ +E +D N ++E R+K L + ++++ V L QLQE + + Sbjct: 1116 VGALAAMERQLQERDDALAALNDRLEEYGREKSALESRTSESVDAVVTLRRQLQERDDAL 1175 Query: 972 ENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQK 1031 L +EE ++ +K +S T + ++ + + L+++D+ + ALN + Sbjct: 1176 AALKDRLEEHSR----------EKSALES--RTSESVDALAAMERQLQERDDALAALNDR 1223 Query: 1032 INNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQ 1091 + + S ES+ ++ L ME + Q L EE + + Sbjct: 1224 LE----EHSREKSALESRTSESVDALAAMERQPQERDDALAALNDRLEEYSREKSALESR 1279 Query: 1092 IKELKETKLTFEMNIPKTEGMI--ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEE 1149 E + +T + + + + + +E S + + ++ L+ Q Sbjct: 1280 TSESVDAVVTLRRQLQERDDALAALKDRLEEHSREKSALESRTSESVDAVVTLRRQ---- 1335 Query: 1150 FIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTE 1209 +QER + A L L+E + LE+ +E G + Q+ + L LN Sbjct: 1336 -LQER---DDALAALKDRLEEYSREKSALESRTSESVGALAAMERQLQERDDALAALNDR 1391 Query: 1210 NDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQRE---ADFQKTEHELRVQLSAFES 1266 + + L S S +VD + L +Q L +R+ A + E + SA ES Sbjct: 1392 LEEYGREKSALESRTSESVD----AVVTLRRQ-LQERDDALAALKDRLEEYGREKSALES 1446 Query: 1267 KYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSE 1326 + + +D++ + ++ + + + +L+++L++ L+ + ++ ++ + + + Sbjct: 1447 RTSESVDALAAMERQLQER---DDALAALKDRLEEHSREKSALESRTSESVDALAAMERQ 1503 Query: 1327 IE--DEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXX 1384 ++ D+ +A +E+ E+ + ++ A LK Sbjct: 1504 LQERDDALAALNDRLEEHSREKSALESRTSESVDALAAMERQLQERDDALAALKDRLEEY 1563 Query: 1385 XXXXXXXXXRVNDAEAKVLELTHQLELKD---SEIYQKTHEYTITLTQRNDEFENVRQQL 1441 R +++ V+ L QL+ +D + + + EY ++ E+ + Sbjct: 1564 SREKSALESRTSESVDAVVTLRRQLQERDDALAALKDRLEEY----SREKSALESRTSES 1619 Query: 1442 VEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSL 1501 V +E E++ LA L ++ E ++ + E V + L ++ E Sbjct: 1620 VGALAAMERQLQERDDALAALNDRLEEYDREKSALESRTS-ESVDAVVTLRRQLQER--- 1675 Query: 1502 NKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFA 1561 + +A LN LEE + + +++ + + ++ + + A +++++ Sbjct: 1676 DDALAALNDRLEEYGREKSALESRTSGSVDALAAMERQLQERDDALAALKDRLEEYGREK 1735 Query: 1562 SDTKQGRDEQLD 1573 S + E +D Sbjct: 1736 SALESRTSESVD 1747 Score = 97.5 bits (232), Expect = 3e-18 Identities = 183/989 (18%), Positives = 418/989 (42%), Gaps = 85/989 (8%) Query: 147 LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXX 206 L + E +AL+ ++ +++ + + L +++ E + A T+ Sbjct: 1192 LESRTSESVDALAAMERQLQERDDALAALNDRLEEHSREKSALESRTSESVDALAAMERQ 1251 Query: 207 ------XXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLL 260 D ++ ++ + + +E D L + ++ +D +++L++ +L Sbjct: 1252 PQERDDALAALNDRLEEYSREKSALESRTSESVDAVVTLRRQLQERDDALAALKD--RLE 1309 Query: 261 EAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLA--KQSIEPSCEEKTEIEEKGSLEI 318 E +R + +LE S+ ++ ++ LA K +E EK+ +E + S + Sbjct: 1310 EHSREKSALE-SRTSESVDAVVTLRRQLQERDDALAALKDRLEEYSREKSALESRTSESV 1368 Query: 319 ANMTELTKKIE----LLEHLNCQIRQTNKELENKLATMGTES-KAVSSPSK----KGSPL 369 + + ++++ L LN ++ + +E ++ L + +ES AV + + + L Sbjct: 1369 GALAAMERQLQERDDALAALNDRLEEYGRE-KSALESRTSESVDAVVTLRRQLQERDDAL 1427 Query: 370 ISRKSGRNTASKMKSPWSQLSSETLNQ--DTDKKINKNE--IAKLEMVIQSLNKDLVDKE 425 + K + KS +SE+++ ++++ + + +A L+ ++ +++ E Sbjct: 1428 AALKDRLEEYGREKSALESRTSESVDALAAMERQLQERDDALAALKDRLEEHSREKSALE 1487 Query: 426 YVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQL 485 SE +D +A L ++H S + T+ E V+ +A ++ QL Sbjct: 1488 SRTSESVDALAAMERQLQERDDALAALNDRLEEHSREKSALESRTS-ESVDALAAMERQL 1546 Query: 486 KQE------LNDEIKDVN-VKDLIEKL--KSAEEQIT-----QLNDEIDAANKNMIKVKS 531 ++ L D +++ + K +E +S + +T Q D+ AA K+ ++ S Sbjct: 1547 QERDDALAALKDRLEEYSREKSALESRTSESVDAVVTLRRQLQERDDALAALKDRLEEYS 1606 Query: 532 NHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVD-YDS 590 K L+ +T ++ ++ +++ + L L+ ++ E + EK L+ + D+ Sbjct: 1607 REKSALES--RTSESVGALAAMERQLQERDDALAALNDRLEEYDREKSALESRTSESVDA 1664 Query: 591 GRMIESDVYKK---MIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADI 647 + + ++ + + + E + S LES+ V L ++++ E +D LA + Sbjct: 1665 VVTLRRQLQERDDALAALNDRLEEYGREKSALESRTSGSVDALAAMERQLQERDDALAAL 1724 Query: 648 SQLQSD--QVCSEIKSVHLEEQIDALSASKKELALVIENLKL--DKEQLYGTIKD-LEN- 701 + + S ++S E +DA+ +++L + L D+ + YG K LE+ Sbjct: 1725 KDRLEEYGREKSALES-RTSESVDAVVTLRRQLQERDDALAALNDRLEEYGREKSALESR 1783 Query: 702 --DKEDIMNKLQNYIQENMD----LTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDA 755 + D + ++ +QE D L D+LE+ S EK + + + ++ Sbjct: 1784 TSESVDALAAMERQLQERDDALAALKDRLEEHSREK-----SVLESRTSESVDALAAMER 1838 Query: 756 KIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSE 815 ++QERD + ++ L ++ LE + D +L R+ + L + E Sbjct: 1839 QLQERDDALAALKDRLEEHSREKSALESRTSESVDAVVTLRRQLQERDDALAALKDRLEE 1898 Query: 816 YTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQH 875 Y ++ L +R + +D + +QL E + L+ + + E L+ S+ Sbjct: 1899 YGREKSALESRTSESVDAVVTLRRQLQERDDALAALKDRLEEYSREKSALESRTSESVDA 1958 Query: 876 YNALVEKAN-RTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLE---IE 931 A+ + R D + K + R+ +S L+ T E +V ++++++ + Sbjct: 1959 LAAMERQLQERDDALAALKDKLEEYGRE-KSALESRTSESVDAVVTLRRQLQERDDALAA 2017 Query: 932 FNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDK 991 N ++E R+K L + ++++ + +E QLQE + + LN +EE + Sbjct: 2018 LNDRLEEHSREKSALESRTSESVDALAAMERQLQERDDALAALNDKLEEYGR-------- 2069 Query: 992 HVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLA 1051 +K +S T + ++ + L L+++D+ + ALN ++ + S ES+ + Sbjct: 2070 --EKSALES--RTSESVDAVVTLRRQLQERDDALAALNDRLE----EHSREKSALESRTS 2121 Query: 1052 QFTTKLENMEEEMQRVSKQLLDSKQHNEE 1080 + L ME ++Q L K EE Sbjct: 2122 ESVDALAAMERQLQERDDALAALKDRLEE 2150 Score = 92.7 bits (220), Expect = 8e-17 Identities = 182/1007 (18%), Positives = 413/1007 (41%), Gaps = 74/1007 (7%) Query: 144 VTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXX 203 V L ++E+D+AL+ L+ +++ L+ + +E + A + Sbjct: 1161 VVTLRRQLQERDDALAALKDRLEEHSREKSALESRTSESVDALAAMERQLQERDDALAAL 1220 Query: 204 XXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAA 263 + ++ E+ A+ A + ++R D +++L + +L E + Sbjct: 1221 NDRLEEHSREKSALESRTSESVDALAAMERQPQER--------DDALAALND--RLEEYS 1270 Query: 264 RFEISLEHSKLAQELEQXXXXXXXXXXXXXXLA--KQSIEPSCEEKTEIEEKGSLEIANM 321 R + +LE S+ ++ ++ LA K +E EK+ +E + S + + Sbjct: 1271 REKSALE-SRTSESVDAVVTLRRQLQERDDALAALKDRLEEHSREKSALESRTSESVDAV 1329 Query: 322 TELTKKIE----LLEHLNCQIRQTNKE---LENKLA-TMGTESKAVSSPSKKGSPLISRK 373 L ++++ L L ++ + ++E LE++ + ++G + ++ L + Sbjct: 1330 VTLRRQLQERDDALAALKDRLEEYSREKSALESRTSESVGALAAMERQLQERDDALAALN 1389 Query: 374 SGRNTASKMKSPWSQLSSETLNQDTDKKINKNE----IAKLEMVIQSLNKDLVDKEYVIS 429 + KS +SE+++ + E +A L+ ++ ++ E S Sbjct: 1390 DRLEEYGREKSALESRTSESVDAVVTLRRQLQERDDALAALKDRLEEYGREKSALESRTS 1449 Query: 430 EKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQE- 488 E +D +A L+ ++H S + T+ E V+ +A ++ QL++ Sbjct: 1450 ESVDALAAMERQLQERDDALAALKDRLEEHSREKSALESRTS-ESVDALAAMERQLQERD 1508 Query: 489 -----LNDEIKDVN---------VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHK 534 LND +++ + + ++ L + E Q+ + +D + AA K+ ++ S K Sbjct: 1509 DALAALNDRLEEHSREKSALESRTSESVDALAAMERQLQERDDAL-AALKDRLEEYSREK 1567 Query: 535 LKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSG-RM 593 L+ +T ++ V +++ + L L ++ E EK L+ + Sbjct: 1568 SALES--RTSESVDAVVTLRRQLQERDDALAALKDRLEEYSREKSALESRTSESVGALAA 1625 Query: 594 IESDVYKK---MIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQL 650 +E + ++ + + + E + S LES+ + V + L+++ E +D LA ++ Sbjct: 1626 MERQLQERDDALAALNDRLEEYDREKSALESRTSESVDAVVTLRRQLQERDDALAALNDR 1685 Query: 651 QSD--QVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQL--YGTIKD-LEN---D 702 + + S ++S +DAL+A +++L + L K++L YG K LE+ + Sbjct: 1686 LEEYGREKSALES-RTSGSVDALAAMERQLQERDDALAALKDRLEEYGREKSALESRTSE 1744 Query: 703 KEDIMNKLQNYIQENMD----LTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQ 758 D + L+ +QE D L D+LE+ EK + + + ++ ++Q Sbjct: 1745 SVDAVVTLRRQLQERDDALAALNDRLEEYGREK-----SALESRTSESVDALAAMERQLQ 1799 Query: 759 ERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTI 818 ERD + ++ L ++ LE + D ++ER+ + L + E++ Sbjct: 1800 ERDDALAALKDRLEEHSREKSVLESRTSESVDALAAMERQLQERDDALAALKDRLEEHSR 1859 Query: 819 QEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNA 878 ++ L +R + +D + +QL E + L+ + + E L+ S+ Sbjct: 1860 EKSALESRTSESVDAVVTLRRQLQERDDALAALKDRLEEYGREKSALESRTSESVDAVVT 1919 Query: 879 LVEKAN-RTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKK--EIEDLEIEFNTQ 935 L + R D + + + R+ + R + L +++ E +D + Sbjct: 1920 LRRQLQERDDALAALKDRLEEYSREKSALESRTSESVDALAAMERQLQERDDALAALKDK 1979 Query: 936 IESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQK 995 +E R+K L + ++++ V L QLQE + + LN +EE ++ L + + Sbjct: 1980 LEEYGREKSALESRTSESVDAVVTLRRQLQERDDALAALNDRLEEHSREKSALESRTSES 2039 Query: 996 QQTQSP--DYTEQYINEINKLNALLKQKDEEIIALNQKIN---NAQVSYMSMVSDYESKL 1050 + ++ + + LN L++ E AL + + +A V+ + + + L Sbjct: 2040 VDALAAMERQLQERDDALAALNDKLEEYGREKSALESRTSESVDAVVTLRRQLQERDDAL 2099 Query: 1051 AQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKE 1097 A +LE E + + +S ++ ++E+DD + LK+ Sbjct: 2100 AALNDRLEEHSREKSALESRTSESVDALAAMERQLQERDDALAALKD 2146 Score = 88.6 bits (210), Expect = 1e-15 Identities = 164/885 (18%), Positives = 363/885 (41%), Gaps = 67/885 (7%) Query: 144 VTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXX 203 V L ++E+D+AL+ L+ +++ L+ + +E + A + Sbjct: 1329 VVTLRRQLQERDDALAALKDRLEEYSREKSALESRTSESVGALAAMERQLQERDDALAAL 1388 Query: 204 XXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAA 263 D ++ + + + +E D L + ++ +D +++L++ +L E Sbjct: 1389 --------NDRLEEYGREKSALESRTSESVDAVVTLRRQLQERDDALAALKD--RLEEYG 1438 Query: 264 RFEISLEHSKLAQELEQXXXXXXXXXXXXXXLA--KQSIEPSCEEKTEIEEKGSLEI--- 318 R + +LE S+ ++ ++ LA K +E EK+ +E + S + Sbjct: 1439 REKSALE-SRTSESVDALAAMERQLQERDDALAALKDRLEEHSREKSALESRTSESVDAL 1497 Query: 319 -ANMTELTKKIELLEHLNCQIRQTNKE---LENKLATMGTESKAVSSP-SKKGSPLISRK 373 A +L ++ + L LN ++ + ++E LE++ + A+ ++ L + K Sbjct: 1498 AAMERQLQERDDALAALNDRLEEHSREKSALESRTSESVDALAAMERQLQERDDALAALK 1557 Query: 374 SGRNTASKMKSPWSQLSSETLNQDTDKKINKNE----IAKLEMVIQSLNKDLVDKEYVIS 429 S+ KS +SE+++ + E +A L+ ++ +++ E S Sbjct: 1558 DRLEEYSREKSALESRTSESVDAVVTLRRQLQERDDALAALKDRLEEYSREKSALESRTS 1617 Query: 430 EKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQE- 488 E +D +A L +++ S + T+ E V+ + ++ QL++ Sbjct: 1618 ESVGALAAMERQLQERDDALAALNDRLEEYDREKSALESRTS-ESVDAVVTLRRQLQERD 1676 Query: 489 -----LNDEIKDVN---------VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHK 534 LND +++ ++ L + E Q+ + +D + AA K+ ++ K Sbjct: 1677 DALAALNDRLEEYGREKSALESRTSGSVDALAAMERQLQERDDAL-AALKDRLEEYGREK 1735 Query: 535 LKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVD-YDSGRM 593 L+ +T ++ V +++ + L L+ ++ E EK L+ + D+ Sbjct: 1736 SALES--RTSESVDAVVTLRRQLQERDDALAALNDRLEEYGREKSALESRTSESVDALAA 1793 Query: 594 IESDVYKK---MIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADIS-Q 649 +E + ++ + +++ E + S+LES+ + V L ++++ E +D LA + + Sbjct: 1794 MERQLQERDDALAALKDRLEEHSREKSVLESRTSESVDALAAMERQLQERDDALAALKDR 1853 Query: 650 LQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQL--YGTIKD-LEN---DK 703 L+ E +DA+ +++L + L K++L YG K LE+ + Sbjct: 1854 LEEHSREKSALESRTSESVDAVVTLRRQLQERDDALAALKDRLEEYGREKSALESRTSES 1913 Query: 704 EDIMNKLQNYIQENMD----LTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQE 759 D + L+ +QE D L D+LE+ S EK + + + ++ ++QE Sbjct: 1914 VDAVVTLRRQLQERDDALAALKDRLEEYSREK-----SALESRTSESVDALAAMERQLQE 1968 Query: 760 RDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQ 819 RD + ++ +L +Y LE + D +L R+ + L E++ + Sbjct: 1969 RDDALAALKDKLEEYGREKSALESRTSESVDAVVTLRRQLQERDDALAALNDRLEEHSRE 2028 Query: 820 EDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNAL 879 + L +R + +D +E+QL E + L K + E L+ S+ L Sbjct: 2029 KSALESRTSESVDALAAMERQLQERDDALAALNDKLEEYGREKSALESRTSESVDAVVTL 2088 Query: 880 VEKAN-RTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKK--EIEDLEIEFNTQI 936 + R D + + + + R+ + R + L +++ E +D ++ Sbjct: 2089 RRQLQERDDALAALNDRLEEHSREKSALESRTSESVDALAAMERQLQERDDALAALKDRL 2148 Query: 937 ESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEEL 981 E R+K L + ++++ + +E QLQE N + V E+ Sbjct: 2149 EEYGREKSALESRTSESVDALAAMERQLQERGNAFNIFDGRVNEI 2193 Score = 84.6 bits (200), Expect = 2e-14 Identities = 183/1086 (16%), Positives = 417/1086 (38%), Gaps = 76/1086 (6%) Query: 497 NVKDLIEKLKSAEEQITQLNDEIDA-ANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNK 555 N + +K K + ITQL + A I+ + KL+L+Q + I+ SK + Sbjct: 435 NTHGVQQKRKPQRKTITQLQCAQNIKALVQQIRKNAEEKLQLQQ-RILINTRSKNMGETQ 493 Query: 556 EIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKA 615 +L++E+ ++ + H DS R + ++ ++ + LK Sbjct: 494 LRQKLSQEIDTKEREDNNRNAKTFTRIKHFYTQDSPR---TPPVQRRLDFSGKEKHLLKD 550 Query: 616 ISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASK 675 + + FD+ L L+++ E +D LA ++ + KSV +++ ++ Sbjct: 551 CPI---KGFDV---LATLERQLQERDDALAALNDKLEEY--GREKSV-----LESRTSES 597 Query: 676 KELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISEL 735 ++ + +E +++ +KD + + L++ E++D+ LE+ E + L Sbjct: 598 VDVVVTLERQLQERDDALAALKDRLEEHSREKSVLESRTSESVDVVVTLERQLQESVDAL 657 Query: 736 LAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSL 795 A ++ ++QERD + ++ L +Y LE + D +L Sbjct: 658 AA---------------MERQLQERDDALAALKDRLEEYGREKSALESRTSESVDAVVTL 702 Query: 796 ERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKN 855 R+ + L E++ ++ L +R + +D +E+QL E + L+ + Sbjct: 703 RRQLQERDDALAALNDRLEEHSREKSALESRTSESVDALAAMERQLQERDDALAALKDRL 762 Query: 856 QILLEENQNLQISLSDMQQHYNALVEKANRTDLA----ESESTKYQTQLRDLESNLKRIT 911 + E L+ S+ A+ + D A + +Y + LES Sbjct: 763 EEHSREKSALESRTSESVDALAAMERQLQERDDALAALKDRLEEYGREKSALESRTSESV 822 Query: 912 HEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNI 971 TL ++ +E +D ++E R+K L + ++++ + +E QLQE + + Sbjct: 823 DAVVTL-SRQLQERDDALAALKDRLEEHSREKSALESRTSESVDALAAMERQLQERDDAL 881 Query: 972 ENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQK 1031 L +EE + +K +S T + ++ + L L+++D+ + ALN + Sbjct: 882 AALKDRLEEYGR----------EKSALES--RTSESVDAVVTLRRQLQERDDALAALNDR 929 Query: 1032 INNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQ 1091 + + S ES+ ++ L ME + Q L K EE + + Sbjct: 930 LE----EHSREKSALESRTSESVDALAAMERQPQERDDALAALKDRLEEYSREKSALESR 985 Query: 1092 IKELKETKLTFEMNIPKTEGMI--ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEE 1149 E + +T + + + + + +E S + + ++ ++ Q Sbjct: 986 TSESVDAVVTLRRQLQERDDALAALKDRLEEYSREKSALESRTSESVDALAAMERQ---- 1041 Query: 1150 FIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTE 1209 +QER + A LN L+E + LE+ +E + ++ + L L Sbjct: 1042 -LQER---DDALAALNDRLEEYSREKSALESRTSESVDALAAMERRLQERDDALAALKDR 1097 Query: 1210 NDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYE 1269 + + L S S +V E Q A E + SA ES+ Sbjct: 1098 LEEYSREKSALESRTSESVG--ALAAMERQLQERDDALAALNDRLEEYGREKSALESRTS 1155 Query: 1270 QLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIE- 1328 + +D+V + ++ + + + +L+++L++ L+ + ++ ++ + + +++ Sbjct: 1156 ESVDAVVTLRRQLQER---DDALAALKDRLEEHSREKSALESRTSESVDALAAMERQLQE 1212 Query: 1329 -DEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXX 1387 D+ +A +E+ E+ ++ A L Sbjct: 1213 RDDALAALNDRLEEHSREKSALESRTSESVDALAAMERQPQERDDALAALNDRLEEYSRE 1272 Query: 1388 XXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKR 1447 R +++ V+ L QL+ +D + + ++ E+ + V+ Sbjct: 1273 KSALESRTSESVDAVVTLRRQLQERDDAL-AALKDRLEEHSREKSALESRTSESVDAVVT 1331 Query: 1448 IEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAE 1507 + E++ LA L+ ++ E + ++ + E V + + ++ E + +A Sbjct: 1332 LRRQLQERDDALAALKDRLEEYSREKSALESRTS-ESVGALAAMERQLQER---DDALAA 1387 Query: 1508 LNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQG 1567 LN LEE + + +++ +VTL ++ + + A +++++ S + Sbjct: 1388 LNDRLEEYGREKSALESRTSESVDAVVTLRRQLQERDDALAALKDRLEEYGREKSALESR 1447 Query: 1568 RDEQLD 1573 E +D Sbjct: 1448 TSESVD 1453 Score = 82.2 bits (194), Expect = 1e-13 Identities = 155/885 (17%), Positives = 359/885 (40%), Gaps = 55/885 (6%) Query: 147 LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQ---IIEAKNKATTXXXXXXXXX 203 L + E +A+ L+ +++ + + L++++ E + +E++ + Sbjct: 1276 LESRTSESVDAVVTLRRQLQERDDALAALKDRLEEHSREKSALESRTSESVDAVVTLRRQ 1335 Query: 204 XXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAA 263 K ++ + A+E+ + L R +L N LE Sbjct: 1336 LQERDDALAALKDRLEEYSREKSALESRTSESVGALAAMERQLQERDDALAALNDRLEEY 1395 Query: 264 RFEISLEHSKLAQELEQXXXXXXXXXXXXXXLA--KQSIEPSCEEKTEIEEKGSLEI--- 318 E S S+ ++ ++ LA K +E EK+ +E + S + Sbjct: 1396 GREKSALESRTSESVDAVVTLRRQLQERDDALAALKDRLEEYGREKSALESRTSESVDAL 1455 Query: 319 -ANMTELTKKIELLEHLNCQIRQTNKE---LENKLATMGTESKAVSSPSKKGSPLISRKS 374 A +L ++ + L L ++ + ++E LE++ + A+ ++ ++ + Sbjct: 1456 AAMERQLQERDDALAALKDRLEEHSREKSALESRTSESVDALAAMERQLQERDDALAALN 1515 Query: 375 GR-NTASKMKSPWSQLSSETLNQ--DTDKKINKNE--IAKLEMVIQSLNKDLVDKEYVIS 429 R S+ KS +SE+++ ++++ + + +A L+ ++ +++ E S Sbjct: 1516 DRLEEHSREKSALESRTSESVDALAAMERQLQERDDALAALKDRLEEYSREKSALESRTS 1575 Query: 430 EKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQE- 488 E +D +A L+ +++ S + T+ E V +A ++ QL++ Sbjct: 1576 ESVDAVVTLRRQLQERDDALAALKDRLEEYSREKSALESRTS-ESVGALAAMERQLQERD 1634 Query: 489 -----LNDEIKDVN-VKDLIEKL--KSAEEQIT---QLNDEIDAANKNMIKVKSNHKLKL 537 LND +++ + K +E +S + +T QL + DA +++ + K Sbjct: 1635 DALAALNDRLEEYDREKSALESRTSESVDAVVTLRRQLQERDDALAALNDRLEEYGREKS 1694 Query: 538 KQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVD-YDSGRMIES 596 +T + ++ +++ + L L ++ E EK L+ + D+ + Sbjct: 1695 ALESRTSGSVDALAAMERQLQERDDALAALKDRLEEYGREKSALESRTSESVDAVVTLRR 1754 Query: 597 DVYKK---MIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADIS-QLQS 652 + ++ + + + E + S LES+ + V L ++++ E +D LA + +L+ Sbjct: 1755 QLQERDDALAALNDRLEEYGREKSALESRTSESVDALAAMERQLQERDDALAALKDRLEE 1814 Query: 653 DQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLY------GTIKDLENDKEDI 706 + E +DAL+A +++L + L K++L ++ ++ D Sbjct: 1815 HSREKSVLESRTSESVDALAAMERQLQERDDALAALKDRLEEHSREKSALESRTSESVDA 1874 Query: 707 MNKLQNYIQENMD----LTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDL 762 + L+ +QE D L D+LE+ EK + + + + ++QERD Sbjct: 1875 VVTLRRQLQERDDALAALKDRLEEYGREK-----SALESRTSESVDAVVTLRRQLQERDD 1929 Query: 763 YIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDE 822 + ++ L +Y LE + D ++ER+ + L + EY ++ Sbjct: 1930 ALAALKDRLEEYSREKSALESRTSESVDALAAMERQLQERDDALAALKDKLEEYGREKSA 1989 Query: 823 LVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEK 882 L +R + +D + +QL E + L + + E L+ S+ A+ + Sbjct: 1990 LESRTSESVDAVVTLRRQLQERDDALAALNDRLEEHSREKSALESRTSESVDALAAMERQ 2049 Query: 883 AN-RTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLE---IEFNTQIES 938 R D + + K + R+ +S L+ T E +V ++++++ + N ++E Sbjct: 2050 LQERDDALAALNDKLEEYGRE-KSALESRTSESVDAVVTLRRQLQERDDALAALNDRLEE 2108 Query: 939 AIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNK 983 R+K L + ++++ + +E QLQE + + L +EE + Sbjct: 2109 HSREKSALESRTSESVDALAAMERQLQERDDALAALKDRLEEYGR 2153 Score = 63.7 bits (148), Expect = 4e-08 Identities = 136/730 (18%), Positives = 302/730 (41%), Gaps = 60/730 (8%) Query: 147 LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQ---IIEAKNKATTXXXXXXXXX 203 L + E +AL+ ++ +++ + + L +++ E + +E++ + Sbjct: 1486 LESRTSESVDALAAMERQLQERDDALAALNDRLEEHSREKSALESRTSESVDALAAMERQ 1545 Query: 204 XXXXXXXXEDTKQQMTKMQENFIAMEA---EWKDEKQRLLKDIESKDVRISSLEEANKLL 260 K ++ + A+E+ E D L + ++ +D +++L++ +L Sbjct: 1546 LQERDDALAALKDRLEEYSREKSALESRTSESVDAVVTLRRQLQERDDALAALKD--RLE 1603 Query: 261 EAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLA--KQSIEPSCEEKTEIEEKGSLEI 318 E +R + +LE S+ ++ + LA +E EK+ +E + S + Sbjct: 1604 EYSREKSALE-SRTSESVGALAAMERQLQERDDALAALNDRLEEYDREKSALESRTSESV 1662 Query: 319 ANMTELTKKIE----LLEHLNCQIRQTNKE---LENKLATMGTESKAVSSP-SKKGSPLI 370 + L ++++ L LN ++ + +E LE++ + A+ ++ L Sbjct: 1663 DAVVTLRRQLQERDDALAALNDRLEEYGREKSALESRTSGSVDALAAMERQLQERDDALA 1722 Query: 371 SRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNE----IAKLEMVIQSLNKDLVDKEY 426 + K + KS +SE+++ + E +A L ++ ++ E Sbjct: 1723 ALKDRLEEYGREKSALESRTSESVDAVVTLRRQLQERDDALAALNDRLEEYGREKSALES 1782 Query: 427 VISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLK 486 SE +D +A L+ ++H S++ T+ E V+ +A ++ QL+ Sbjct: 1783 RTSESVDALAAMERQLQERDDALAALKDRLEEHSREKSVLESRTS-ESVDALAAMERQLQ 1841 Query: 487 QE------LNDEIKDVN-VKDLIEKL--KSAEEQIT-----QLNDEIDAANKNMIKVKSN 532 + L D +++ + K +E +S + +T Q D+ AA K+ ++ Sbjct: 1842 ERDDALAALKDRLEEHSREKSALESRTSESVDAVVTLRRQLQERDDALAALKDRLEEYGR 1901 Query: 533 HKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVD-YDSG 591 K L+ +T ++ V +++ + L L ++ E EK L+ + D+ Sbjct: 1902 EKSALES--RTSESVDAVVTLRRQLQERDDALAALKDRLEEYSREKSALESRTSESVDAL 1959 Query: 592 RMIESDVYKK---MIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADIS 648 +E + ++ + +++ E + S LES+ + V + L+++ E +D LA ++ Sbjct: 1960 AAMERQLQERDDALAALKDKLEEYGREKSALESRTSESVDAVVTLRRQLQERDDALAALN 2019 Query: 649 -QLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKL--DKEQLYGTIKD-LEN--- 701 +L+ E +DAL+A +++L + L DK + YG K LE+ Sbjct: 2020 DRLEEHSREKSALESRTSESVDALAAMERQLQERDDALAALNDKLEEYGREKSALESRTS 2079 Query: 702 DKEDIMNKLQNYIQENMD----LTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKI 757 + D + L+ +QE D L D+LE+ S EK + + + ++ ++ Sbjct: 2080 ESVDAVVTLRRQLQERDDALAALNDRLEEHSREK-----SALESRTSESVDALAAMERQL 2134 Query: 758 QERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYT 817 QERD + ++ L +Y LE + D ++ER+ + G+ +E Sbjct: 2135 QERDDALAALKDRLEEYGREKSALESRTSESVDALAAMERQLQERGNAFNIFDGRVNEIC 2194 Query: 818 IQEDELVNRL 827 +++ L RL Sbjct: 2195 MEKSSLGFRL 2204 >UniRef50_Q23Q31 Cluster: Viral A-type inclusion protein repeat containing protein; n=1; Tetrahymena thermophila SB210|Rep: Viral A-type inclusion protein repeat containing protein - Tetrahymena thermophila SB210 Length = 1823 Score = 125 bits (301), Expect = 1e-26 Identities = 221/1176 (18%), Positives = 483/1176 (41%), Gaps = 90/1176 (7%) Query: 446 DTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKL 505 DT ++ QLE H SL +++I + +++L Q L D+I+ + Sbjct: 499 DTNTSRYQLEPDVHKT--SLRSSQLQERALHQILEEKDRLIQRLEDKIQRN------DSY 550 Query: 506 KSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSD-----SNKEIVRL 560 S E I + N + + ++K + ++ +K N K D + ++ L Sbjct: 551 YSKIEHILRNNSNYNEIQTLLNQIKERDQREIDYREKQFQNAIKQKDLLLKQQDGDLQSL 610 Query: 561 TEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLE 620 + L L+Q+ +EL+E LQ D + S+ + IE E L + R K ++ Sbjct: 611 RDNLFILNQQNSELKERLRILQTQ----DIQSQLLSNKQIQNIE-EALDKQRFKYEEKIQ 665 Query: 621 SQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELAL 680 + + ++ I+ + + + L LQ+D+ + EE +K E + Sbjct: 666 NYRSEIESLKGIINAEKKKNQQILLQTELLQNDK---DYIQQQFEESEQRYYQAKNEAEM 722 Query: 681 VIENLKLDK----EQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAE---KIS 733 ++E L K I+ LEN+ E + N E L + +K + + K + Sbjct: 723 LLEKLHQAKLANATNERNRIQSLENEIEQLRQNQLNIYSEEGKLIQQYKKQNEDLTKKYN 782 Query: 734 ELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRY 793 L + E+ K++ +++L E IE E + K L+ + +E RY Sbjct: 783 HLQKLLEENEKQKLE-DLKKQQDAHQKELQ-EKIEKEKLEQKEPEQNLQPVVQDIESNRY 840 Query: 794 SLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQK 853 ++ +A + Q+ + +E +EL +D+++ + +I+H N +LQ+ Sbjct: 841 KMKYEAKK-----QKYKNLKTEMKNMYEELKQMTQENIDNNQKINSLNQQIQHYNHQLQQ 895 Query: 854 KNQILLEENQNLQISLSDMQQHYNALVEKANRT--DLAESESTKYQTQLR---DLESNLK 908 NQ L LQ S D A++EK D + KYQ +L+ D NLK Sbjct: 896 ANQQL----HLLQSSNKDNVNSRIAMIEKIKDRFEDQLKQSQQKYQEELQLQADQIQNLK 951 Query: 909 -------RITHEHQTLIVQKKKEIEDLEIEFNTQIESA------IRDKKVLNEKYEKNIE 955 R + Q I +K ++I L+++ Q E ++ K+ L++K + + Sbjct: 952 AEIERKMRDLQKLQNTIQEKDEDINSLKVQIQEQKEKQKKSSKNLQPKEDLSQKVKSLNQ 1011 Query: 956 YVTQLEAQLQEYKNNIENLNMN---VEELNKMNLELIDKHVQKQQTQSPDYTEQYINEIN 1012 ++Q E++++E + ++++ +E+ K + +K +Q+ +TQ + +Q NE + Sbjct: 1012 ALSQKESKIEELQKELKDIKSEKDEIEKTTKKKQQNFEKKIQEIETQKKQFEDQIFNESD 1071 Query: 1013 KLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLL 1072 K L + +++ N+++ Y + +Y+ +QF K + E+ + +++ Sbjct: 1072 KSTILFESTLKQLRIENKELER---KYFEEIENYKIIQSQFCEKEMLYKNEIDDLQRKIQ 1128 Query: 1073 DSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMI--ISSTIEPMSDDANNVDX 1130 + K H I ++ +++L+E + I + +S + + N + Sbjct: 1129 ELKHHVTYDNINQQKVSRNVQQLQEEVILAREQIRDLSLQLKDVSESAFQLERQLNEIIQ 1188 Query: 1131 XXXXXXXXXXXLK-VQEEEEFIQERSVLQEQ-SAKLNTELQECYTKIIQLETLNTELTGH 1188 K +++E E ++ RS ++Q ++N EL+ + +++ ++ Sbjct: 1189 KYEESQQQIIKYKAIEDEMEQLKRRSQREQQYKEQINEELEALKQYVQEIQRQKDNISVQ 1248 Query: 1189 DVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREA 1248 + E I + K + L L EL + + +++ + Q + Sbjct: 1249 IKLKDEAIQEGKEYQQDLIKFMKELEQKYQELENQTTGQSYDLNSQVS-YYIQQVDLLTF 1307 Query: 1249 DFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRN 1308 + ++ + + S ++ ++ D QEE K T+E S +K K++ L+ Sbjct: 1308 ENKRIHDKNQTINSDLAAQIKESKDLKARLIQEE-QKSKTLEAQLSQYDK--TKKKQLQT 1364 Query: 1309 LQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTE----NQSYKQMQE 1364 L+ ++A+ + EIL E E ++ + NQ YK+ E Sbjct: 1365 LKSQFAEQKDYNEILYQEKEALQIKIEEMHQIMIDSEQIYQTHINIVKSKFNQDYKEFIE 1424 Query: 1365 QSILNI-----NEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQK 1419 Q I ++ +K V++ EAK+ ++++++L ++ +K Sbjct: 1425 QVNAKIKFFIAKKDQVDVKSKVLKMFERYLEEIPTVSEKEAKIKSMSNKIQLLKDQLAEK 1484 Query: 1420 THEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHEN--ANHYETMQ 1477 +E I Q + + V + + ++ + + H + + Sbjct: 1485 QNE--IENQQNKGNYNPNQTNNVNNANNAVNKAVKPSNKYTLETIVEHAKIIVQKQDIEK 1542 Query: 1478 KESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLN 1537 +EI++ K + E K +E SLNKQ E ++ ++++ A + + L+N++ + Sbjct: 1543 LFTEIQQYKQLVE--QKQSEIDSLNKQGHEKDEKIKQQSAFIQKSKEDLQNEKQRADKIQ 1600 Query: 1538 DEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLD 1573 +E +Q +++ +Q + ++T + ++E+L+ Sbjct: 1601 EEKDEIQKQIKS----LQAQLKAKNNTIEQKNEELN 1632 Score = 107 bits (258), Expect = 2e-21 Identities = 166/835 (19%), Positives = 371/835 (44%), Gaps = 71/835 (8%) Query: 299 SIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKA 358 S++ +E+ E ++K S + +L++K++ L Q +EL+ +L + +E Sbjct: 977 SLKVQIQEQKEKQKKSSKNLQPKEDLSQKVKSLNQALSQKESKIEELQKELKDIKSEKDE 1036 Query: 359 VSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLN 418 + +KK +K ++++ Q + N ++DK E ++ I+ N Sbjct: 1037 IEKTTKKKQQNFEKK-----IQEIETQKKQFEDQIFN-ESDKSTILFESTLKQLRIE--N 1088 Query: 419 KDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEI 478 K+L K + ++ + ++ + +++ Q HV + + ++ Sbjct: 1089 KELERKYF----EEIENYKIIQSQFCEKEMLYKNEIDDLQRKIQELKHHVTYDNINQQKV 1144 Query: 479 AKVQEQLKQEL---NDEIKDVN--VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNH 533 ++ +QL++E+ ++I+D++ +KD+ E E Q+ ++ + + + + +IK K+ Sbjct: 1145 SRNVQQLQEEVILAREQIRDLSLQLKDVSESAFQLERQLNEIIQKYEESQQQIIKYKAIE 1204 Query: 534 KLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNL--QLHLVD--YD 589 +++Q+++ S+ KE ++ EEL L Q V E++ +K N+ Q+ L D Sbjct: 1205 D-EMEQLKRR----SQREQQYKE--QINEELEALKQYVQEIQRQKDNISVQIKLKDEAIQ 1257 Query: 590 SGRMIESDVYKKMIEMENL---AETRLKAISL-LESQKFDLVQELHILQQKYDEVEDK-- 643 G+ + D+ K M E+E E + S L SQ +Q++ +L + + DK Sbjct: 1258 EGKEYQQDLIKFMKELEQKYQELENQTTGQSYDLNSQVSYYIQQVDLLTFENKRIHDKNQ 1317 Query: 644 ---------LADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYG 694 + + L++ + E KS LE Q+ +KK+ +++ + +++ Y Sbjct: 1318 TINSDLAAQIKESKDLKARLIQEEQKSKTLEAQLSQYDKTKKKQLQTLKS-QFAEQKDYN 1376 Query: 695 TIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKI-QTQFGI 753 I L +KE + K++ Q +D E++ I+ + +K N + + I Q I Sbjct: 1377 EI--LYQEKEALQIKIEEMHQIMID----SEQIYQTHINIVKSKFNQDYKEFIEQVNAKI 1430 Query: 754 DAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAY 813 I ++D +++S++ K R +++ E + S+ K L L EKQ Sbjct: 1431 KFFIAKKDQV--DVKSKVLKMFERYLEEIPTVSEKEAKIKSMSNKIQLLKDQLAEKQNEI 1488 Query: 814 SEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQ 873 + + N+ + + + V K + E ++ ++ + Q+++ +++Q Sbjct: 1489 ENQQNKGNYNPNQTNNVNNANNAVNKAVKPSNKYTLETIVEHAKIIVQKQDIEKLFTEIQ 1548 Query: 874 QHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFN 933 Q+ + +K + D + + +++ + +++ + Q Q+ +I++ + E Sbjct: 1549 QYKQLVEQKQSEIDSLNKQGHEKDEKIKQQSAFIQKSKEDLQN-EKQRADKIQEEKDEIQ 1607 Query: 934 TQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHV 993 QI+S K N E+ E + ++ A L++Y + ++ N EE N +LI Sbjct: 1608 KQIKSLQAQLKAKNNTIEQKNEELNKI-AFLKQYNDQLKEDNAKKEEQIAQNEKLIKNQR 1666 Query: 994 QK-----QQTQSPDYTEQYINEI-NKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYE 1047 + +Q Q + + Y+ E+ K N K K+E I+ LN Q S+ +D Sbjct: 1667 DQIGKLTKQIQEIERKDDYVKEMQEKYN---KMKEEAILVLNDN-KKYQEQIASLKNDIV 1722 Query: 1048 SK--LAQFTTKLENMEEEMQRVSKQLLDSKQHNEE----LQILVREQDDQIKELK 1096 K L Q +LE ++++V ++L ++ N++ L ++ +D ++LK Sbjct: 1723 RKDLLLQDKIQLEEKHIKLKQVYEKLKENNSKNKDNIKKLTATIKMKDQVNQQLK 1777 Score = 91.1 bits (216), Expect = 2e-16 Identities = 189/1030 (18%), Positives = 442/1030 (42%), Gaps = 108/1030 (10%) Query: 309 EIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSP 368 E+++ I N ++ + ++H N Q++Q N++L + V+S Sbjct: 864 ELKQMTQENIDNNQKINSLNQQIQHYNHQLQQANQQLH---LLQSSNKDNVNSRIAMIEK 920 Query: 369 LISRKSGRNTASKMK-SPWSQLSSETL-NQDTDKKINKNEIAKLEMVIQSLNKDLVDKEY 426 + R + S+ K QL ++ + N + + ++ KL+ IQ ++D+ + Sbjct: 921 IKDRFEDQLKQSQQKYQEELQLQADQIQNLKAEIERKMRDLQKLQNTIQEKDEDINSLKV 980 Query: 427 VISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLI-HVGTNTEDV----NEIAKV 481 I E+ K+ L +++ +Q + S I + +D+ +EI K Sbjct: 981 QIQEQKEKQKKSSKNLQPKEDLSQKVKSLNQALSQKESKIEELQKELKDIKSEKDEIEKT 1040 Query: 482 QEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVK--SNHKLKLKQ 539 ++ +Q +I+++ + K E+QI +D+ ++ +K N +L+ K Sbjct: 1041 TKKKQQNFEKKIQEIETQK-----KQFEDQIFNESDKSTILFESTLKQLRIENKELERKY 1095 Query: 540 MQKTIDNFSKVSDS--NKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESD 597 ++ I+N+ + KE++ E+ L +K+ EL+ H V YD+ + + Sbjct: 1096 FEE-IENYKIIQSQFCEKEML-YKNEIDDLQRKIQELK--------HHVTYDN--INQQK 1143 Query: 598 VYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCS 657 V + + +++ + + L Q DL +L + + ++E +L +I Q + Sbjct: 1144 VSRNVQQLQ-------EEVILAREQIRDLSLQLKDVSESAFQLERQLNEIIQKYEESQQQ 1196 Query: 658 EIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQ---NYI 714 IK +E++++ L + E + + E L +++++ K++I +++ I Sbjct: 1197 IIKYKAIEDEMEQLKRRSQREQQYKEQINEELEALKQYVQEIQRQKDNISVQIKLKDEAI 1256 Query: 715 QENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKY 774 QE + L K + EL K E + +++++ YI+ ++ L+ Sbjct: 1257 QEGKEYQQDLIKF----MKELEQKYQELENQTTGQSYDLNSQV---SYYIQQVDL-LTFE 1308 Query: 775 KSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHD 834 RI +++ + D ++ D +QE+QK+ T++ A L +D Sbjct: 1309 NKRI--HDKNQTINSDLAAQIKESKDLKARLIQEEQKS---KTLE--------AQLSQYD 1355 Query: 835 RVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESEST 894 + +KQL ++ + E + N+IL +E + LQI + +M Q + +SE Sbjct: 1356 KTKKKQLQTLKSQFAEQKDYNEILYQEKEALQIKIEEMHQ------------IMIDSEQI 1403 Query: 895 KYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNI 954 YQT + ++S + +++ I Q +I+ I Q++ + K+ E+Y + I Sbjct: 1404 -YQTHINIVKS---KFNQDYKEFIEQVNAKIK-FFIAKKDQVDVKSKVLKMF-ERYLEEI 1457 Query: 955 EYVTQLEAQLQEYKNNIENL-NMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEI-- 1011 V++ EA+++ N I+ L + E+ N++ + + QT + + +N+ Sbjct: 1458 PTVSEKEAKIKSMSNKIQLLKDQLAEKQNEIENQQNKGNYNPNQTNNVNNANNAVNKAVK 1517 Query: 1012 --NKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSK 1069 NK + +II Q I E K ++ + + E+ +++ + Sbjct: 1518 PSNKYTLETIVEHAKIIVQKQDIEKLFTEIQQYKQLVEQKQSEIDSLNKQGHEKDEKIKQ 1577 Query: 1070 QLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVD 1129 Q ++ E+LQ +++ D+I+E K+ ++ ++ + + ++TIE +++ N + Sbjct: 1578 QSAFIQKSKEDLQ-NEKQRADKIQEEKD-EIQKQIKSLQAQLKAKNNTIEQKNEELNKIA 1635 Query: 1130 XXXXXXXXXXXXLKVQEEEEFIQERSVL---QEQSAKLNTELQECYTKIIQLETLNTELT 1186 ++EE+ Q ++ ++Q KL ++QE K ++ + + Sbjct: 1636 FLKQYNDQLKED-NAKKEEQIAQNEKLIKNQRDQIGKLTKQIQEIERKDDYVKEMQEKYN 1694 Query: 1187 GHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELW---KQHL 1243 +N K EQ+ + ++++ L+ I ++++ ++ +++ K++ Sbjct: 1695 KMKEEAILVLNDNKKYQEQIASLKNDIVRKDLLLQDKIQ--LEEKHIKLKQVYEKLKENN 1752 Query: 1244 AQREADFQKTEHELRVQLSAFESKYEQLLDS---VQSSTQEETNKIVTMEQ--------- 1291 ++ + + +K ++++ + Q+ D Q ++ +TN ++ E Sbjct: 1753 SKNKDNIKKLTATIKMKDQVNQQLKSQVFDDEDISQDQSENKTNNVIKQENWKKSPVRFT 1812 Query: 1292 VTSLQNKLQD 1301 T+ QN+LQD Sbjct: 1813 KTTSQNQLQD 1822 Score = 89.8 bits (213), Expect = 5e-16 Identities = 179/928 (19%), Positives = 390/928 (42%), Gaps = 82/928 (8%) Query: 629 ELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLD 688 E+ Q +D+ ED I ++ E+K +H+E ++ K++ L + L Sbjct: 392 EIEPFQIIFDQYEDNEKRIEKMYIKNSDPELKDMHVEFKL----FDTKKIRLSPQCFVLA 447 Query: 689 KEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQ 748 ++ I +E +I ++L+ +Q+ M +T E + +INH+ + Sbjct: 448 PNEIKEVI--IELIPCEITSRLE--LQDFMFVTAN----QGEFEKRISIQINHKSLQRFD 499 Query: 749 TQFGIDAKIQERDLYIENIESELSKYKSRICRLEESI--AVMEDRRYSLERKADQLGSYL 806 T ++ Q +E ++ K R +L+E ++E++ ++R D+ + Sbjct: 500 TN---TSRYQ--------LEPDVHKTSLRSSQLQERALHQILEEKDRLIQRLEDK----I 544 Query: 807 QEKQKAYS--EYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQ---KKNQILLEE 861 Q YS E+ ++ + N + L+ +++ E+ EI++ K+ Q K+ +LL++ Sbjct: 545 QRNDSYYSKIEHILRNNSNYNEIQTLL--NQIKERDQREIDYREKQFQNAIKQKDLLLKQ 602 Query: 862 NQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNL---KRITHEHQTLI 918 SL D N + ++L E QTQ D++S L K+I + + L Sbjct: 603 QDGDLQSLRD-----NLFILNQQNSELKE-RLRILQTQ--DIQSQLLSNKQIQNIEEALD 654 Query: 919 VQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNV 978 Q+ K E ++ + ++IES K ++N + +KN + + Q E LQ K+ I+ Sbjct: 655 KQRFKYEEKIQ-NYRSEIESL---KGIINAEKKKNQQILLQTEL-LQNDKDYIQ---QQF 706 Query: 979 EELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVS 1038 EE + + ++ + NE N++ +L + EI L Q N Sbjct: 707 EESEQRYYQAKNEAEMLLEKLHQAKLANATNERNRIQSL----ENEIEQLRQNQLNIYSE 762 Query: 1039 YMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLL-DSKQHNEELQILVREQDDQIK-ELK 1096 ++ Y+ + T K ++++ ++ KQ L D K+ + Q ++E+ ++ K E K Sbjct: 763 EGKLIQQYKKQNEDLTKKYNHLQKLLEENEKQKLEDLKKQQDAHQKELQEKIEKEKLEQK 822 Query: 1097 ETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSV 1156 E + + + E E N+ + QE + Q+ + Sbjct: 823 EPEQNLQPVVQDIESNRYKMKYEAKKQKYKNLKTEMKNMYEELKQM-TQENIDNNQKINS 881 Query: 1157 LQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQI-NQLKSKLEQLNTENDNLLS 1215 L +Q N +LQ+ ++ L++ N + + E+I ++ + +L+Q + L Sbjct: 882 LNQQIQHYNHQLQQANQQLHLLQSSNKDNVNSRIAMIEKIKDRFEDQLKQSQQKYQEELQ 941 Query: 1216 TVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSV 1275 A+ ++ + ++++ ++ +L + + +++ D + L+VQ+ E K +Q S Sbjct: 942 LQADQIQNLKAEIERKMRDLQKL-QNTIQEKDEDI----NSLKVQIQ--EQKEKQKKSSK 994 Query: 1276 QSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFX 1335 +E+ + ++V SL L KE + LQ++ D+ ++ + + + ++ F Sbjct: 995 NLQPKEDLS-----QKVKSLNQALSQKESKIEELQKELKDIKSEKDEIEKTTKKKQQNFE 1049 Query: 1336 XXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRV 1395 + E+ + E ++ + EN +L++ + Sbjct: 1050 KKIQEIETQKKQFEDQIFNESDKSTILFESTLKQLRIENKELERKYFEEIENYKIIQSQF 1109 Query: 1396 NDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEK 1455 + E L+ K E+ I + + + ++++++ ++I DL+ + Sbjct: 1110 CEKEMLYKNEIDDLQRKIQELKHHVTYDNINQQKVSRNVQQLQEEVILAREQIRDLSLQL 1169 Query: 1456 E--SELAI-LRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAE-LNKA 1511 + SE A L +++E YE + + +I + K IE+ ++ +Q E +N+ Sbjct: 1170 KDVSESAFQLERQLNEIIQKYE--ESQQQIIKYKAIEDEMEQLKRRSQREQQYKEQINEE 1227 Query: 1512 LEEEVAKTNEMQTALENQEIEIVTLNDE 1539 LE E+Q +N ++I L DE Sbjct: 1228 LEALKQYVQEIQRQKDNISVQI-KLKDE 1254 Score = 76.6 bits (180), Expect = 5e-12 Identities = 161/898 (17%), Positives = 389/898 (43%), Gaps = 68/898 (7%) Query: 140 QLGDVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKD---QIIEAKNKATT-- 194 ++ D+ L NTI+EKD ++ L+V+++ + + + K+ Q +++ N+A + Sbjct: 957 KMRDLQKLQNTIQEKDEDINSLKVQIQEQKEKQKKSSKNLQPKEDLSQKVKSLNQALSQK 1016 Query: 195 -XXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSL 253 ++ ++ K Q+NF E + +K++ I ++ + + L Sbjct: 1017 ESKIEELQKELKDIKSEKDEIEKTTKKKQQNFEKKIQEIETQKKQFEDQIFNESDKSTIL 1076 Query: 254 EEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEK 313 E+ L+ R E K +E+E L K I+ + E++ Sbjct: 1077 FEST--LKQLRIENKELERKYFEEIEN-YKIIQSQFCEKEMLYKNEIDDLQRKIQELKHH 1133 Query: 314 GSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISR- 372 + + N ++++ ++ L+ R+ ++L +L + S++ ++ + +I + Sbjct: 1134 VTYDNINQQKVSRNVQQLQEEVILAREQIRDLSLQLKDV---SESAFQLERQLNEIIQKY 1190 Query: 373 KSGRNTASKMKS---PWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVIS 429 + + K K+ QL + + K+ E+ L+ +Q + + + I Sbjct: 1191 EESQQQIIKYKAIEDEMEQLKRRSQREQQYKEQINEELEALKQYVQEIQRQKDNISVQIK 1250 Query: 430 EKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQL--KQ 487 KD + +L+ ++Q+ + N++ I +V + Sbjct: 1251 LKDEAIQEGKEYQQDLIKFMKELEQKYQELENQTTGQSYDLNSQVSYYIQQVDLLTFENK 1310 Query: 488 ELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNF 547 ++D+ + +N DL ++K +++ +L E + ++ K K KQ+Q F Sbjct: 1311 RIHDKNQTIN-SDLAAQIKESKDLKARLIQEEQKSKTLEAQLSQYDKTKKKQLQTLKSQF 1369 Query: 548 SKVSDSN------KEIVRL-TEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIE--SDV 598 ++ D N KE +++ EE+H + ++ + N+ + D IE + Sbjct: 1370 AEQKDYNEILYQEKEALQIKIEEMHQIMIDSEQIYQTHINIVKSKFNQDYKEFIEQVNAK 1429 Query: 599 YKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSE 658 K I ++ + + K + + E ++E+ + +K +++ +++ QL DQ+ + Sbjct: 1430 IKFFIAKKDQVDVKSKVLKMFER----YLEEIPTVSEKEAKIK-SMSNKIQLLKDQLAEK 1484 Query: 659 IKSVHLEEQIDALSASKKELALVIENL--KLDKEQLYGTIKDLENDKEDIMNKLQNYIQE 716 + ++ + ++ N K K T++ + + I+ K I++ Sbjct: 1485 QNEIENQQNKGNYNPNQTNNVNNANNAVNKAVKPSNKYTLETIVEHAKIIVQKQD--IEK 1542 Query: 717 NMDLTDKLEKMSAEKISEL--LAKINHEEQSKIQTQFGIDAKIQERDLYIENIESE-LSK 773 + +++ +K SE+ L K HE+ KI+ Q K +E DL E ++ + + Sbjct: 1543 LFTEIQQYKQLVEQKQSEIDSLNKQGHEKDEKIKQQSAFIQKSKE-DLQNEKQRADKIQE 1601 Query: 774 YKSRICRLEESI-AVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMD 832 K I + +S+ A ++ + ++E+K ++L KQ Y++ ++ED + + Sbjct: 1602 EKDEIQKQIKSLQAQLKAKNNTIEQKNEELNKIAFLKQ--YND-QLKEDN-AKKEEQIAQ 1657 Query: 833 HDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESE 892 ++++++ Q +I K++Q+ +E + + +MQ+ YN + E+A L ++ Sbjct: 1658 NEKLIKNQRDQIGKLTKQIQE-----IERKDDY---VKEMQEKYNKMKEEA---ILVLND 1706 Query: 893 STKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEK 952 + KYQ Q+ L++++ R + L++Q K ++E+ I+ Q+ +++ N+ K Sbjct: 1707 NKKYQEQIASLKNDIVR-----KDLLLQDKIQLEEKHIKLK-QVYEKLKENNSKNKDNIK 1760 Query: 953 NIEYVTQLEAQL-QEYKNNI---ENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQ 1006 + +++ Q+ Q+ K+ + E+++ + E NK N + ++ +K + T Q Sbjct: 1761 KLTATIKMKDQVNQQLKSQVFDDEDISQDQSE-NKTNNVIKQENWKKSPVRFTKTTSQ 1817 Score = 58.8 bits (136), Expect = 1e-06 Identities = 131/711 (18%), Positives = 283/711 (39%), Gaps = 76/711 (10%) Query: 890 ESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKK---VL 946 + E +Q E N KRI + I E++D+ +EF IR VL Sbjct: 390 DMEIEPFQIIFDQYEDNEKRI---EKMYIKNSDPELKDMHVEFKLFDTKKIRLSPQCFVL 446 Query: 947 --NEKYEKNIEYVT---QLEAQLQEYK----NNIENLNMNVEELNKMNLELIDKHVQKQQ 997 NE E IE + +LQ++ N E ++N +L+ D + + Q Sbjct: 447 APNEIKEVIIELIPCEITSRLELQDFMFVTANQGEFEKRISIQINHKSLQRFDTNTSRYQ 506 Query: 998 TQSPDYTEQYIN----EINKLNALLKQKDEEIIALNQKI--NNAQVSYMSMVSDYESKLA 1051 + PD + + + L+ +L++KD I L KI N++ S + + S Sbjct: 507 LE-PDVHKTSLRSSQLQERALHQILEEKDRLIQRLEDKIQRNDSYYSKIEHILRNNSNYN 565 Query: 1052 QFTTKLENMEEEMQR-VSKQLLDSKQHNEELQILVREQDDQIKELKETKLTF-EMNIPKT 1109 + T L ++E QR + + + ++ +L+++QD ++ L++ + N Sbjct: 566 EIQTLLNQIKERDQREIDYREKQFQNAIKQKDLLLKQQDGDLQSLRDNLFILNQQNSELK 625 Query: 1110 EGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQ 1169 E + I T + S +N K EE+ RS ++ +N E + Sbjct: 626 ERLRILQTQDIQSQLLSNKQIQNIEEALDKQRFKY--EEKIQNYRSEIESLKGIINAEKK 683 Query: 1170 ECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVD 1229 + ++Q E L + D + Q+Q + + + Q E + LL + + + +++A + Sbjct: 684 KNQQILLQTELLQND---KDYI-QQQFEESEQRYYQAKNEAEMLLEKLHQAK--LANATN 737 Query: 1230 QRG-FEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVT 1288 +R + E + L Q + + E +L + ++ + E L + K++ Sbjct: 738 ERNRIQSLENEIEQLRQNQLNIYSEEGKL---IQQYKKQNEDL-----TKKYNHLQKLLE 789 Query: 1289 MEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXX 1348 + L++ + ++ H + LQEK I + ++E ++ Sbjct: 790 ENEKQKLEDLKKQQDAHQKELQEK---------IEKEKLEQKEPEQNLQPVVQDIESNRY 840 Query: 1349 XXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQ 1408 + Q YK ++ + + N+ EE Q+ + + ++N ++ HQ Sbjct: 841 KMKYEAKKQKYKNLKTE-MKNMYEELKQMTQENIDNNQ-------KINSLNQQIQHYNHQ 892 Query: 1409 LELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHE 1468 L+ + +++ + R E ++ + + K+ + Y++E +L Sbjct: 893 LQQANQQLHLLQSSNKDNVNSRIAMIEKIKDRFEDQLKQSQQ-KYQEELQL--------- 942 Query: 1469 NANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALEN 1528 A+ + ++ E E +++ +++L I E ++ + L ++E+ K + L+ Sbjct: 943 QADQIQNLKAEIE-RKMRDLQKLQNTIQEK---DEDINSLKVQIQEQKEKQKKSSKNLQP 998 Query: 1529 QEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKE 1579 +E L+ ++ +L + SKI++ D K +DE T K+ Sbjct: 999 KE----DLSQKVKSLNQALSQKESKIEELQKELKDIKSEKDEIEKTTKKKQ 1045 >UniRef50_P49454 Cluster: Centromere protein F; n=15; Eutheria|Rep: Centromere protein F - Homo sapiens (Human) Length = 3210 Score = 125 bits (301), Expect = 1e-26 Identities = 273/1350 (20%), Positives = 579/1350 (42%), Gaps = 118/1350 (8%) Query: 244 ESKDVRISSLEEANKLLEAARFEISLEHSKLAQELE-QXXXXXXXXXXXXXXLAKQSIEP 302 E+ +EE L E R SLE KL +++E Q L+ + E Sbjct: 1636 ETPSAPAKGVEELESLCEVYRQ--SLE--KLEEKMESQGIMKNKEIQELEQLLSSERQEL 1691 Query: 303 SCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNK-ELENKLATMGTESKAVSS 361 C K + E + +T +T +E+ L + +QT + LE ++A + + +SS Sbjct: 1692 DCLRKQYLSENEQWQ-QKLTSVT--LEMESKLAAEKKQTEQLSLELEVARLQLQGLDLSS 1748 Query: 362 PSKKGSPLISRKSGRNTASKM-KSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKD 420 S G GRN + + K S+ + T D + +K+ L + I+ + + Sbjct: 1749 RSLLGIDTEDAIQGRNESCDISKEHTSETTERTPKHDVHQICDKDAQQDLNLDIEKITET 1808 Query: 421 LVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAK 480 K + G+D + + GP+ + + +I Sbjct: 1809 GAVKPTGECSGEQSPDTNYEPP-GEDKTQGSSECISELSFSGPNALVPMDFLGNQEDIHN 1867 Query: 481 VQEQLKQELNDEIKDVNV-KDLIEKLKSAEEQITQLNDEIDAANKN-MIKVKSNHKLKLK 538 +Q ++K+ N+ ++ ++V +D K++S ++ +L+ ++ M K+++ Sbjct: 1868 LQLRVKETSNENLRLLHVIEDRDRKVESLLNEMKELDSKLHLQEVQLMTKIEA-----CI 1922 Query: 539 QMQKTIDNFSKV-SDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESD 597 +++K + K SD ++++ + + L Q+V E +L++H D S I + Sbjct: 1923 ELEKIVGELKKENSDLSEKLEYFSCDHQELLQRVETSEGLNSDLEMH-ADKSSREDIGDN 1981 Query: 598 VYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVE-DKLADISQLQSDQVC 656 V K + +S + S+K + E L+ + V+ +KL L+ D Sbjct: 1982 VAKVNDSWKERFLDVENELSRIRSEKASIEHEALYLEADLEVVQTEKLC----LEKDNEN 2037 Query: 657 SEIKSVHLEEQIDALSASKKELALVIENLK-----LDK--EQLYGTIKDLENDKEDIMNK 709 + V LEE++ +++ + +L ++ + LD+ E++ ++LE+ + + ++ Sbjct: 2038 KQKVIVCLEEELSVVTSERNQLRGELDTMSKKTTALDQLSEKMKEKTQELESHQSECLHC 2097 Query: 710 LQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIES 769 +Q E + T+ L+ +S++ +SELL H Q K+Q+ + +EN + Sbjct: 2098 IQVAEAEVKEKTELLQTLSSD-VSELLKDKTHL-QEKLQSLEKDSQALSLTKCELENQIA 2155 Query: 770 ELSKYKSRICRLEESI-AVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDEL----- 823 +L+K K + + ES+ A + + Y + L + L EK + + ++E+ Sbjct: 2156 QLNKEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRR 2215 Query: 824 -VNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEK 882 + +L V ++ D EK+ L I + KE +++N L ++ +NL+ L +++ ++ Sbjct: 2216 GIEKLRVRIEAD---EKKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQELVILD 2272 Query: 883 ANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRD 942 A + AE E+ K TQ+ ++ +LK + TL +K+ + ++ E Q+ D Sbjct: 2273 AENSK-AEVETLK--TQIEEMARSLKVFELDLVTLRSEKENLTKQIQ-EKQGQLSEL--D 2326 Query: 943 KKVLNEKYEKNIEYVTQLEAQL-QEYKNNIENLNMNVEELNKMNLELI-DKHVQKQQTQS 1000 K L ++ +E Q E Q+ +E K +E L ++ELN+ L D+ + K QS Sbjct: 2327 K--LLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQS 2384 Query: 1001 PD----YTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTK 1056 D Q N I KL A L+ +++ + + Q++ S++ + L + + Sbjct: 2385 LDPPIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKE---------SEHHADLLK--GR 2433 Query: 1057 LENMEEEMQ--RVSKQ--LLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGM 1112 +EN+E E++ R +++ L+++ E++ L + + + L+ +L ++ ++E Sbjct: 2434 VENLERELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGLEL--DVVTIRSEKE 2491 Query: 1113 IISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECY 1172 +++ ++ + + ++ + ++E+E +Q + L T+L+E Sbjct: 2492 NLTNELQKEQERISELEIINSSFEN----ILQEKEQEKVQMKEKSSTAMEMLQTQLKELN 2547 Query: 1173 TKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRG 1232 ++ L + Q+ L+ + QL D + L+SS++ + + Sbjct: 2548 ERVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQE-- 2605 Query: 1233 FEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQV 1292 E KQ L +++ + + +++++ Q EQL+ + +Q E + EQ Sbjct: 2606 ---VEDGKQKLEKKDEEISRLKNQIQDQ--------EQLVSKL---SQVEGEHQLWKEQN 2651 Query: 1293 TSLQNKLQDKEEHLRNLQEKYADVINQIEILRS---EIEDE-------KVAFXXXXXXXX 1342 L+N + E+ ++ LQ K A + + +E+L+S +E+E K++F Sbjct: 2652 LELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEKVNKMT 2711 Query: 1343 XXXXXXXXDLRTENQSYKQMQEQSILNINE--ENAQLKKSSXXXXXXXXXXXXRVNDAEA 1400 ++ Q ++QE+ N QL N Sbjct: 2712 AKETELQREMHEMAQKTAELQEELSGEKNRLAGELQLLLEEIKSSKDQLKELTLENSELK 2771 Query: 1401 KVLELTHQLEL-KDSEIYQKTHEYTITLTQRNDEFENV-----RQQLVEYEKRIEDLTYE 1454 K L+ H+ ++ K+ ++ ++ EY + L + + + + +Q VE + E LT Sbjct: 2772 KSLDCMHKDQVEKEGKVREEIAEYQLRLHEAEKKHQALLLDTNKQYEVEIQTYREKLT-S 2830 Query: 1455 KESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEE 1514 KE L+ +L++ + E + + +++EEL K T+ +L K V +L K E Sbjct: 2831 KEECLSSQKLEIDLLKSSKEELNNSLK-ATTQILEEL--KKTKMDNL-KYVNQLKKENER 2886 Query: 1515 EVAKTNEMQTALENQEIEIVTLNDEITNLQ 1544 K + + + E E L E++ LQ Sbjct: 2887 AQGKMKLLIKSCKQLEEEKEILQKELSQLQ 2916 Score = 119 bits (287), Expect = 6e-25 Identities = 207/951 (21%), Positives = 423/951 (44%), Gaps = 82/951 (8%) Query: 235 EKQRLLKDIESKDVRISSLEEANKLLEAARFEISLE---HSKLAQELEQXXXXXXXXXXX 291 EK L KD E+K I LEE ++ + R ++ E SK L+Q Sbjct: 2027 EKLCLEKDNENKQKVIVCLEEELSVVTSERNQLRGELDTMSKKTTALDQLSEKMKEKTQE 2086 Query: 292 XXXLAKQSI------EPSCEEKTEIEEKGSLEIANM----TELTKKIELLEHLNCQIRQT 341 + + E +EKTE+ + S +++ + T L +K++ LE + + T Sbjct: 2087 LESHQSECLHCIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLT 2146 Query: 342 NKELENKLATMGTESKAVSSPSKKGSPLISRKSGR--NTASKMKSPWSQLSSETLN-QDT 398 ELEN++A + E + + S+ +S N + +++ + L T Sbjct: 2147 KCELENQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSST 2206 Query: 399 DKKIN--KNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEH 456 ++++ + I KL + I++ K K+ I+EK K + L+ E Sbjct: 2207 QEEVHQLRRGIEKLRVRIEADEK----KQLHIAEKLKERERENDSLKDK---VENLEREL 2259 Query: 457 QQHMEGPSLIHVGT-NTEDVNEIAKVQ-EQLKQELND-EIKDVNVKDLIEKL-KSAEEQI 512 Q E L+ + N++ E K Q E++ + L E+ V ++ E L K +E+ Sbjct: 2260 QMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQ 2319 Query: 513 TQLN--DEIDAANKNMIKVKSNHKLKLKQMQKTIDNF--SKVSDSNKEIVRLT--EELHH 566 QL+ D++ ++ K++++ K ++++K+ KT +++ + N+ + L +E+ Sbjct: 2320 GQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQEIMK 2379 Query: 567 LSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDL 626 +++ + E+ + + ++ R+ E+D K++ ++ L E+ A LL+ + +L Sbjct: 2380 ATEQSLDPPIEEEHQLRNSIEKLRARL-EADEKKQLCVLQQLKESEHHA-DLLKGRVENL 2437 Query: 627 VQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLK 686 +EL I + + + L+++ E+++ L+ +I+ ++ S + L L + ++ Sbjct: 2438 ERELEIARTNQEH--------AALEAENSKGEVET--LKAKIEGMTQSLRGLELDVVTIR 2487 Query: 687 LDKEQLYGTI-KDLENDKE-DIMNK-LQNYIQEN-MDLTDKLEKMSA--EKISELLAKIN 740 +KE L + K+ E E +I+N +N +QE + EK S E + L ++N Sbjct: 2488 SEKENLTNELQKEQERISELEIINSSFENILQEKEQEKVQMKEKSSTAMEMLQTQLKELN 2547 Query: 741 HEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKAD 800 + Q AK Q +E +E E ++ + + + V++ L ++ + Sbjct: 2548 ERVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVE 2607 Query: 801 QLGSYLQEKQKAYSEYTIQ---EDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQI 857 L++K + S Q +++LV++L+ + ++ ++Q LE+ + EL++K Q+ Sbjct: 2608 DGKQKLEKKDEEISRLKNQIQDQEQLVSKLSQVEGEHQLWKEQNLELRNLTVELEQKIQV 2667 Query: 858 LLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTL 917 L +N +LQ +L +Q Y L + T + + + ++ E+ L+R HE Sbjct: 2668 LQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEKVNKMTAKETELQREMHEMAQK 2727 Query: 918 IVQKKKEIED----LEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIEN 973 + ++E+ L E +E K L E +N E L+ +K+ +E Sbjct: 2728 TAELQEELSGEKNRLAGELQLLLEEIKSSKDQLKELTLENSELKKSLDCM---HKDQVEK 2784 Query: 974 LNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDE-------EII 1026 EE+ + L L + +K Q D +QY EI L K+E EI Sbjct: 2785 EGKVREEIAEYQLRLHEAE-KKHQALLLDTNKQYEVEIQTYREKLTSKEECLSSQKLEID 2843 Query: 1027 AL---NQKINNAQVSYMSMVSDY-ESKL--AQFTTKLENMEEEMQRVSKQLLDS-KQHNE 1079 L +++NN+ + ++ + ++K+ ++ +L+ E Q K L+ S KQ E Sbjct: 2844 LLKSSKEELNNSLKATTQILEELKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCKQLEE 2903 Query: 1080 ELQILVRE----QDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDAN 1126 E +IL +E Q Q K+ T + +++ TE + T+E + +A+ Sbjct: 2904 EKEILQKELSQLQAAQEKQKTGTVMDTKVDELTTEIKELKETLEEKTKEAD 2954 Score = 99.1 bits (236), Expect = 9e-19 Identities = 216/1150 (18%), Positives = 475/1150 (41%), Gaps = 117/1150 (10%) Query: 463 PSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAA 522 PS + G+ ED+ E + + ++ L E+K + K + L A +N Sbjct: 155 PSQYYSGSKYEDLKEKYNKEVEERKRLEAEVKALQAKKASQTLPQA-----TMN------ 203 Query: 523 NKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQ 582 ++++ + +++ + Q +KT + S S+S + +R + S + E+ + LQ Sbjct: 204 HRDIARHQASSSVFSWQQEKTPSHLS--SNSQRTPIRRDFSASYFSGE-QEVTPSRSTLQ 260 Query: 583 LHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVED 642 + D +S S + +++ + I+ LE + +E+ K+ E++ Sbjct: 261 IGKRDANSSFFDNSSSPHLLDQLKAQNQELRNKINELELRLQGHEKEMKGQVNKFQELQL 320 Query: 643 KL--ADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLE 700 +L A + ++ ++V ++ + + AS K AL + LK E L ++ E Sbjct: 321 QLEKAKVELIEKEKVLNKCRDELVRTTAQYDQASTKYTALE-QKLKKLTEDLSCQRQNAE 379 Query: 701 NDKEDIMNKL---QNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKI 757 + + + K+ + QE + + + ++ ++ A++ E Q + A++ Sbjct: 380 SARCSLEQKIKEKEKEFQEELSRQQRSFQTLDQECIQMKARLTQELQQAKNMHNVLQAEL 439 Query: 758 QERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQL---GSYLQ--EKQKA 812 + + +E+ L ++K ++CR E++ + + L R +++ + L+ +QKA Sbjct: 440 DKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKA 499 Query: 813 YSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDM 872 E E EL N L E+ ++ ++ ++E ++ L+E N Q + + Sbjct: 500 -REVCHLEAELKNIKQCLNQSQNFAEE--MKAKNTSQETMLRD---LQEKINQQENSLTL 553 Query: 873 QQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQ---KKKEIEDLE 929 ++ A+ + + D ++ K + + L L + E + L+ KKKE E+L+ Sbjct: 554 EKLKLAVADLEKQRDCSQDLLKKREHHIEQLNDKLSKTEKESKALLSALELKKKEYEELK 613 Query: 930 IEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELI 989 +K + + +N + +TQ+E++ + ++ I +L + + I Sbjct: 614 -----------EEKTLFSCWKSENEKLLTQMESEKENLQSKINHLE------TCLKTQQI 656 Query: 990 DKHVQKQQTQSPDYTEQYIN-EINKLNALLKQKDEEI-------IALNQKINNAQVSYMS 1041 H ++ ++ + + ++ EI L+ +L K E+ + L QK + + Sbjct: 657 KSHEYNERVRTLEMDRENLSVEIRNLHNVLDSKSVEVETQKLAYMELQQKAEFSDQKHQK 716 Query: 1042 MVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLT 1101 + + K +Q T ++E++E ++Q +S +++D + ++L D +K K+ L Sbjct: 717 EIENMCLKTSQLTGQVEDLEHKLQLLSNEIMDKDRCYQDLHAEYESLRDLLKS-KDASLV 775 Query: 1102 FEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEE-----FIQER-- 1154 N ++ M N+ +++ ++ +Q R Sbjct: 776 --TNEDHQRSLLAFDQQPAMHHSFANIIGEQGSMPSERSECRLEADQSPKNSAILQNRVD 833 Query: 1155 --SVLQEQSAKLNTELQECYTKIIQLE-TLNTELTGHDVVNQEQINQLKSKLEQLNTEND 1211 E ++N++LQ+ +++Q++ + L + ++Q + + ++ +L + Sbjct: 834 SLEFSLESQKQMNSDLQKQCEELVQIKGEIEENLMKAEQMHQSFVAETSQRISKLQEDTS 893 Query: 1212 NLLSTVAELRSS----------ISSAVDQRGFEIAELWK-QHLAQREADFQKTEHELRVQ 1260 + VAE S+ ++ V+ EI EL K HL + D K L Sbjct: 894 AHQNVVAETLSALENKEKELQLLNDKVETEQAEIQELKKSNHLLE---DSLKELQLLSET 950 Query: 1261 LSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQI 1320 LS + + ++ + +E T + T++++ + L ++ +L E +A+ I++ Sbjct: 951 LSLEKKEMSSIISLNKREIEELTQENGTLKEINA---SLNQEKMNLIQKSESFANYIDER 1007 Query: 1321 EILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQS-----ILNINEENA 1375 E SE+ D+ DL +Q YK QE++ +LN Sbjct: 1008 EKSISELSDQYKQEKLILLQRCEETGNAYEDL---SQKYKAAQEKNSKLECLLNECTSLC 1064 Query: 1376 QLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFE 1435 + +K+ + + E +Q + + E Q+ +T Q N + E Sbjct: 1065 ENRKNELEQLKEAFAKEHQEFLTKLAFAEERNQNLMLELETVQQALRSEMTDNQNNSKSE 1124 Query: 1436 --NVRQQLV-------EYEKRIEDLTYEKESELAILRLKMHENAN-HYETMQ---KESEI 1482 ++Q+++ + +K + DL E E + +++ K HE N E ++ KE E Sbjct: 1125 AGGLKQEIMTLKEEQNKMQKEVNDLLQENEQLMKVMKTK-HECQNLESEPIRNSVKERES 1183 Query: 1483 ER----VKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLND 1538 ER K +L VK S N Q+ +L L + K E + E + E+ T+ Sbjct: 1184 ERNQCNFKPQMDLEVKEISLDSYNAQLVQLEAMLRNKELKLQESEKEKECLQHELQTIRG 1243 Query: 1539 --EITNLQNM 1546 E +NLQ+M Sbjct: 1244 DLETSNLQDM 1253 Score = 89.4 bits (212), Expect = 7e-16 Identities = 204/1121 (18%), Positives = 462/1121 (41%), Gaps = 106/1121 (9%) Query: 483 EQLKQELNDEIKDVNVKDLIEKLKSAE-EQITQLNDEIDAANKNMIKVKSNHKLKLKQMQ 541 E LK++ N E+++ K L ++K+ + ++ +Q + ++++ + +++ + Q + Sbjct: 165 EDLKEKYNKEVEER--KRLEAEVKALQAKKASQTLPQATMNHRDIARHQASSSVFSWQQE 222 Query: 542 KTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKK 601 KT + S S+S + +R + S + E+ + LQ+ D +S S Sbjct: 223 KTPSHLS--SNSQRTPIRRDFSASYFSGE-QEVTPSRSTLQIGKRDANSSFFDNSSSPHL 279 Query: 602 MIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKL--ADISQLQSDQVCSEI 659 + +++ + I+ LE + +E+ K+ E++ +L A + ++ ++V ++ Sbjct: 280 LDQLKAQNQELRNKINELELRLQGHEKEMKGQVNKFQELQLQLEKAKVELIEKEKVLNKC 339 Query: 660 KSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKL---QNYIQE 716 + + AS K AL + LK E L ++ E+ + + K+ + QE Sbjct: 340 RDELVRTTAQYDQASTKYTALE-QKLKKLTEDLSCQRQNAESARCSLEQKIKEKEKEFQE 398 Query: 717 NMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKS 776 + + + ++ ++ A++ E Q + A++ + + +E+ L ++K Sbjct: 399 ELSRQQRSFQTLDQECIQMKARLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQ 458 Query: 777 RICRLEESIAVMEDRRYSLERKADQL---GSYLQE--KQKAYSEYTIQEDELVNRLAVLM 831 ++CR E++ + + L R +++ + L+ +QKA E E EL N L Sbjct: 459 KLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKA-REVCHLEAELKNIKQCLN 517 Query: 832 DHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAES 891 E+ ++ ++ ++E ++ L+E N Q + +++ A+ + + D ++ Sbjct: 518 QSQNFAEE--MKAKNTSQETMLRD---LQEKINQQENSLTLEKLKLAVADLEKQRDCSQD 572 Query: 892 ESTKYQTQLRDLESNLKRITHEHQTLIVQ---KKKEIEDLEIEFNTQIESAIRDKKVLNE 948 K + + L L + E + L+ KKKE E+L+ E K + + Sbjct: 573 LLKKREHHIEQLNDKLSKTEKESKALLSALELKKKEYEELKEE-----------KTLFSC 621 Query: 949 KYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYI 1008 +N + +TQ+E++ + ++ I +L + + I H ++ ++ + + + Sbjct: 622 WKSENEKLLTQMESEKENLQSKINHLE------TCLKTQQIKSHEYNERVRTLEMDRENL 675 Query: 1009 N-EINKLNALLKQKDEEI-------IALNQKINNAQVSYMSMVSDYESKLAQFTTKLENM 1060 + EI L+ +L K E+ + L QK + + + + K +Q T ++E++ Sbjct: 676 SVEIRNLHNVLDSKSVEVETQKLAYMELQQKAEFSDQKHQKEIENMCLKTSQLTGQVEDL 735 Query: 1061 EEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEP 1120 E ++Q +S +++D + ++L D +K + +T N ++ Sbjct: 736 EHKLQLLSNEIMDKDRCYQDLHAEYESLRDLLKSKDASLVT---NEDHQRSLLAFDQQPA 792 Query: 1121 MSDDANNVDXXXXXXXXXXXXLKVQEEEE-----FIQER----SVLQEQSAKLNTELQEC 1171 M N+ +++ ++ +Q R E ++N++LQ+ Sbjct: 793 MHHSFANIIGEQGSMPSERSECRLEADQSPKNSAILQNRVDSLEFSLESQKQMNSDLQKQ 852 Query: 1172 YTKIIQLE-TLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSA--- 1227 +++Q++ + L + ++Q + + ++ +L + + VAE S++ + Sbjct: 853 CEELVQIKGEIEENLMKAEQMHQSFVAETSQRISKLQEDTSAHQNVVAETLSALENKEKE 912 Query: 1228 -------VDQRGFEIAELWKQ-HLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSST 1279 V+ EI EL K HL + D K L LS + + ++ + Sbjct: 913 LQLLNDKVETEQAEIQELKKSNHLLE---DSLKELQLLSETLSLEKKEMSSIISLNKREI 969 Query: 1280 QEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXX 1339 +E T + T++++ + L ++ +L E +A+ I++ E SE+ D+ Sbjct: 970 EELTQENGTLKEINA---SLNQEKMNLIQKSESFANYIDEREKSISELSDQYKQEKLILL 1026 Query: 1340 XXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAE 1399 DL +Q YK QE+ N + L ++ +A Sbjct: 1027 QRCEETGNAYEDL---SQKYKAAQEK-----NSKLECLLNECTSLCENRKNELEQLKEAF 1078 Query: 1400 AKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESEL 1459 AK HQ E + + + L E E V+Q L + D +SE Sbjct: 1079 AK----EHQ-EFLTKLAFAEERNQNLML-----ELETVQQAL---RSEMTDNQNNSKSEA 1125 Query: 1460 AILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKT 1519 L+ ++ MQKE + + + V T+ N + + +++E ++ Sbjct: 1126 GGLKQEIMTLKEEQNKMQKEVNDLLQENEQLMKVMKTKHECQNLESEPIRNSVKERESER 1185 Query: 1520 NEM----QTALENQEIEIVTLNDEITNLQNMVRASSSKIQK 1556 N+ Q LE +EI + + N ++ L+ M+R K+Q+ Sbjct: 1186 NQCNFKPQMDLEVKEISLDSYNAQLVQLEAMLRNKELKLQE 1226 Score = 87.4 bits (207), Expect = 3e-15 Identities = 184/929 (19%), Positives = 377/929 (40%), Gaps = 74/929 (7%) Query: 681 VIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKIN 740 +++ LK ++L I +LE + +++ + + +L +LEK E I E +N Sbjct: 279 LLDQLKAQNQELRNKINELELRLQGHEKEMKGQVNKFQELQLQLEKAKVELI-EKEKVLN 337 Query: 741 HEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRI-CRLEESIAVMEDRRYSLERKA 799 ++T A+ + +E +L K + C+ + + E R SLE+K Sbjct: 338 KCRDELVRT----TAQYDQASTKYTALEQKLKKLTEDLSCQRQNA----ESARCSLEQK- 388 Query: 800 DQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILL 859 ++EK+K + E EL + D+ + + E ++ + + +L Sbjct: 389 ------IKEKEKEFQE------ELSRQQRSFQTLDQECIQMKARLTQELQQAKNMHNVLQ 436 Query: 860 EENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIV 919 E L ++ + +K R + A S + +LR +K+ + ++ Sbjct: 437 AELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSE 496 Query: 920 QKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVE 979 QK +E+ LE E + + + E KN T L LQE N EN ++ +E Sbjct: 497 QKAREVCHLEAELKNIKQCLNQSQNFAEEMKAKNTSQETMLR-DLQEKINQQEN-SLTLE 554 Query: 980 ELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSY 1039 K+ L + D ++KQ+ S D ++ + I +LN L + ++E AL + + Y Sbjct: 555 ---KLKLAVAD--LEKQRDCSQDLLKKREHHIEQLNDKLSKTEKESKALLSALELKKKEY 609 Query: 1040 MSMVSD---YESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELK 1096 + + + ++ L ME E + + ++ + + QI E +++++ L+ Sbjct: 610 EELKEEKTLFSCWKSENEKLLTQMESEKENLQSKINHLETCLKTQQIKSHEYNERVRTLE 669 Query: 1097 ETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSV 1156 + + I ++ S ++E + ++ K E E + S Sbjct: 670 MDRENLSVEIRNLHNVLDSKSVEVETQKLAYMELQQKAEFSDQKHQK--EIENMCLKTSQ 727 Query: 1157 LQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLST 1216 L Q L +LQ +I+ + +L + + LKSK L T D+ S Sbjct: 728 LTGQVEDLEHKLQLLSNEIMDKDRCYQDLHAE---YESLRDLLKSKDASLVTNEDHQRSL 784 Query: 1217 VA-----ELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQL 1271 +A + S ++ + ++G +E + L EAD Q ++ + +++ + L Sbjct: 785 LAFDQQPAMHHSFANIIGEQGSMPSERSECRL---EAD-QSPKNS-----AILQNRVDSL 835 Query: 1272 LDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEK 1331 S++S Q ++ E++ ++ ++ EE+L ++ + + + S+++++ Sbjct: 836 EFSLESQKQMNSDLQKQCEELVQIKGEI---EENLMKAEQMHQSFVAETSQRISKLQEDT 892 Query: 1332 VAFXXXXXXXXXXXXXXXXDLRTENQSYK----QMQEQSILN--INEENAQLKKSSXXXX 1385 A +L+ N + ++QE N + + +L+ S Sbjct: 893 SAHQNVVAETLSALENKEKELQLLNDKVETEQAEIQELKKSNHLLEDSLKELQLLSETLS 952 Query: 1386 XXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYE 1445 ++ + ++ ELT + EI ++ + L Q+++ F N + E E Sbjct: 953 LEKKEMSSIISLNKREIEELTQENGTL-KEINASLNQEKMNLIQKSESFAN---YIDERE 1008 Query: 1446 KRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQV 1505 K I +L+ + + E IL + E N YE + ++ + + K +L + E SL + Sbjct: 1009 KSISELSDQYKQEKLILLQRCEETGNAYEDLSQKYKAAQEK-NSKLECLLNECTSLCENR 1067 Query: 1506 AELNKALEEEVAKTN-EMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKH-VSFASD 1563 + L+E AK + E T L E L E+ +Q +R+ + Q + S A Sbjct: 1068 KNELEQLKEAFAKEHQEFLTKLAFAEERNQNLMLELETVQQALRSEMTDNQNNSKSEAGG 1127 Query: 1564 TKQG----RDEQLDNTMNKELLDAVPRAE 1588 KQ ++EQ N M KE+ D + E Sbjct: 1128 LKQEIMTLKEEQ--NKMQKEVNDLLQENE 1154 Score = 81.4 bits (192), Expect = 2e-13 Identities = 226/1233 (18%), Positives = 519/1233 (42%), Gaps = 133/1233 (10%) Query: 381 KMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXX 440 ++++ ++L + + K N+ +L++ ++ +L++KE V+++ Sbjct: 289 ELRNKINELELRLQGHEKEMKGQVNKFQELQLQLEKAKVELIEKEKVLNKCRDELVRTTA 348 Query: 441 XXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQ---ELNDEIKDVN 497 T L+ + ++ E S + + K++E+ K+ EL+ + + Sbjct: 349 QYDQASTKYTALEQKLKKLTEDLSCQRQNAESARCSLEQKIKEKEKEFQEELSRQQRSFQ 408 Query: 498 VKD---------LIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFS 548 D L ++L+ A+ L E+D ++++N + +++ + F Sbjct: 409 TLDQECIQMKARLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQKLCRAEQAFQ 468 Query: 549 KVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENL 608 E+ R EE+ + + E+K HL ++ + + + +N Sbjct: 469 ASQIKENELRRSMEEMKKENNLLKSHSEQKAREVCHL------EAELKNIKQCLNQSQNF 522 Query: 609 AETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEI----KSVHL 664 AE + E+ DL ++++ + + KLA ++ L+ + CS+ + H+ Sbjct: 523 AEEMKAKNTSQETMLRDLQEKINQQENSLTLEKLKLA-VADLEKQRDCSQDLLKKREHHI 581 Query: 665 EEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKL 724 E+ D LS ++KE ++ L+L K K+ E KE+ + EN L L Sbjct: 582 EQLNDKLSKTEKESKALLSALELKK-------KEYEELKEE-KTLFSCWKSENEKL---L 630 Query: 725 EKMSAEKISELLAKINHEEQSKIQTQ----FGIDAKIQERDLYIENIESELSKYKSRICR 780 +M +EK L +KINH E ++TQ + +++ ++ EN+ E+ + + Sbjct: 631 TQMESEK-ENLQSKINHLETC-LKTQQIKSHEYNERVRTLEMDRENLSVEIRNLHNVLDS 688 Query: 781 LEESIAVMEDRRYSLERKADQLGSYLQEKQKAY----SEYTIQEDELVNRLAVL----MD 832 + + L++KA+ Q++ + S+ T Q ++L ++L +L MD Sbjct: 689 KSVEVETQKLAYMELQQKAEFSDQKHQKEIENMCLKTSQLTGQVEDLEHKLQLLSNEIMD 748 Query: 833 HDRVVEKQLLEIEHEN-KELQKKNQILLEENQNLQISLSDMQQ----HY---NALVEKAN 884 DR + L E+E+ ++L K L N++ Q SL Q H+ N + E+ + Sbjct: 749 KDRCYQD--LHAEYESLRDLLKSKDASLVTNEDHQRSLLAFDQQPAMHHSFANIIGEQGS 806 Query: 885 ----RTD--LAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIES 938 R++ L +S K L++ +L+ + + +K+ E+L ++ +IE Sbjct: 807 MPSERSECRLEADQSPKNSAILQNRVDSLEFSLESQKQMNSDLQKQCEEL-VQIKGEIEE 865 Query: 939 AIRDKKVLNEKY-EKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQ 997 + + +++ + + + +++L+ ++N + +E K L+L++ V+ +Q Sbjct: 866 NLMKAEQMHQSFVAETSQRISKLQEDTSAHQNVVAETLSALENKEK-ELQLLNDKVETEQ 924 Query: 998 TQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKL 1057 + I E+ K N LL+ +E+ L++ ++ + S++S + ++ + T + Sbjct: 925 AE--------IQELKKSNHLLEDSLKELQLLSETLSLEKKEMSSIISLNKREIEELTQEN 976 Query: 1058 ENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKEL----KETKLTFEMNIPKTEGMI 1113 ++E ++++ ++ Q +E + E++ I EL K+ KL +T Sbjct: 977 GTLKEINASLNQEKMNLIQKSESFANYIDEREKSISELSDQYKQEKLILLQRCEETGNAY 1036 Query: 1114 I------------SSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQS 1161 +S +E + ++ ++ +E +EF+ + + +E++ Sbjct: 1037 EDLSQKYKAAQEKNSKLECLLNECTSLCENRKNELEQLKEAFAKEHQEFLTKLAFAEERN 1096 Query: 1162 AKLNTELQECYTKIIQLETLNTELTGHDVVN-QEQINQLKSKLEQLNTENDNLLSTVAEL 1220 L EL+ + T N + + +++I LK + ++ E ++LL +L Sbjct: 1097 QNLMLELETVQQALRSEMTDNQNNSKSEAGGLKQEIMTLKEEQNKMQKEVNDLLQENEQL 1156 Query: 1221 RSSISSAVDQRGFEIAELWKQHLAQREADFQ----KTEHELRVQLSAFESKYEQLLDSVQ 1276 + + + + E +E + + +RE++ K + +L V+ + +S QL+ Sbjct: 1157 MKVMKTKHECQNLE-SEPIRNSVKERESERNQCNFKPQMDLEVKEISLDSYNAQLVQLEA 1215 Query: 1277 SSTQEETNKIVTMEQVTSLQNKLQDKEEHLR--NLQEKYADVINQIEILRSEIEDEKVAF 1334 +E + ++ LQ++LQ L NLQ+ + I+ ++ + E++ ++ Sbjct: 1216 MLRNKELKLQESEKEKECLQHELQTIRGDLETSNLQDMQSQEISGLKDCEIDAEEKYIS- 1274 Query: 1335 XXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXR 1394 +L T +Q +N+ N +L+K Sbjct: 1275 -------------GPHELSTSQNDNAHLQCSLQTTMNKLN-ELEKICEILQAEKYELVTE 1320 Query: 1395 VNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYE 1454 +ND+ ++ + T ++ E+ + +E I ND+ + +LVE E E Sbjct: 1321 LNDSRSECITATRKMA---EEVGKLLNEVKIL----NDDSGLLHGELVEDIPGGE--FGE 1371 Query: 1455 KESELAILRLKMHENANHYETM---QKESEIERVKLIEELNVKITESVSLNKQVAELNKA 1511 + +E + L + +N YE + KE ++ +L E+ +E L+ Q +++ Sbjct: 1372 QPNEQHPVSLAPLDESNSYEHLTLSDKEVQMHFAELQEKFLSLQSEHKILHDQHCQMS-- 1429 Query: 1512 LEEEVAKTNEMQTALENQEIEIVTLNDEITNLQ 1544 +K +E+QT +++ + E + L+ + N Q Sbjct: 1430 -----SKMSELQTYVDSLKAENLVLSTNLRNFQ 1457 Score = 81.0 bits (191), Expect = 2e-13 Identities = 167/797 (20%), Positives = 350/797 (43%), Gaps = 80/797 (10%) Query: 233 KDEKQRLLKDIESKDVRISSLEE-----ANKLLEAARFEISLEHSKLAQELEQXXXXXXX 287 ++E +L + IE VRI + E+ A KL E R SL+ + LE+ Sbjct: 2207 QEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDK--VENLERELQMSEE 2264 Query: 288 XXXXXXXLAKQSIEPSCEEKTEIEEKG-SLEIANMTELTKKIELLEHLNCQIRQTNKELE 346 A+ S KT+IEE SL++ + +T + E E+L QI++ +L Sbjct: 2265 NQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEK-ENLTKQIQEKQGQL- 2322 Query: 347 NKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNE 406 ++L + + K++ ++ I +S + +++ +L+ D++I K Sbjct: 2323 SELDKLLSSFKSLLEEKEQAEIQIKEES-KTAVEMLQNQLKELNEAVAALCGDQEIMKAT 2381 Query: 407 IAKLEMVIQSLN--KDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQL------QLEHQQ 458 L+ I+ + ++ ++K E D + A L LE + Sbjct: 2382 EQSLDPPIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRVENLEREL 2441 Query: 459 HMEGPSLIHVGTNTE----DVNEIAKVQEQLKQELND-EIKDVNVK----DLIEKLKSAE 509 + + H E +V + E + Q L E+ V ++ +L +L+ + Sbjct: 2442 EIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTNELQKEQ 2501 Query: 510 EQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQ 569 E+I++L + I+++ +N+++ K K+++K+ T + KE+ LH+ Q Sbjct: 2502 ERISEL-EIINSSFENILQEKEQEKVQMKEKSSTA--MEMLQTQLKELNERVAALHN-DQ 2557 Query: 570 KVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQE 629 + + +E+ + Q+ ++ + ++++ L E + I +L+S L+QE Sbjct: 2558 EACKAKEQNLSSQVECLELEKAQLLQG-----------LDEAKNNYI-VLQSSVNGLIQE 2605 Query: 630 LHILQQKYDEVEDKLADI-SQLQS-DQVCSEIKSVHLEEQIDALSASKKELALVIENLKL 687 + +QK ++ +++++ + +Q+Q +Q+ S++ V E Q+ KE L + NL + Sbjct: 2606 VEDGKQKLEKKDEEISRLKNQIQDQEQLVSKLSQVEGEHQL------WKEQNLELRNLTV 2659 Query: 688 DKEQLYGTIKDLENDKEDIMNKLQNY---IQENMDLTDKLEKMS-AEKISELLAKINHEE 743 + EQ ++ +D + LQ+ ++ ++LT K++KMS EK++++ AK E Sbjct: 2660 ELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELT-KMDKMSFVEKVNKMTAK-ETEL 2717 Query: 744 QSKIQTQFGIDAKIQERDLYIEN-IESELSKYKSRICRLEESIAVMEDRRYSLERKADQL 802 Q ++ A++QE +N + EL I ++ + + L++ D + Sbjct: 2718 QREMHEMAQKTAELQEELSGEKNRLAGELQLLLEEIKSSKDQLKELTLENSELKKSLDCM 2777 Query: 803 GSYLQEKQ----KAYSEYTIQEDELVNR-LAVLMDHDRVVEKQLLEIEHENKELQKKNQI 857 EK+ + +EY ++ E + A+L+D ++ E +EI+ ++L K + Sbjct: 2778 HKDQVEKEGKVREEIAEYQLRLHEAEKKHQALLLDTNKQYE---VEIQTYREKLTSKEEC 2834 Query: 858 LLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQT--QLRDLESNLKRITHEHQ 915 L + + + S ++ N+L KA L E + TK + L+ +R + + Sbjct: 2835 LSSQKLEIDLLKSSKEELNNSL--KATTQILEELKKTKMDNLKYVNQLKKENERAQGKMK 2892 Query: 916 TLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLN 975 LI K+ E+ EI ++ + + EK + T ++ ++ E I+ L Sbjct: 2893 LLIKSCKQLEEEKEI-----LQKELSQLQAAQEKQKTG----TVMDTKVDELTTEIKELK 2943 Query: 976 MNVEELNKMNLELIDKH 992 +EE K E +DK+ Sbjct: 2944 ETLEEKTKEADEYLDKY 2960 Score = 79.8 bits (188), Expect = 6e-13 Identities = 165/839 (19%), Positives = 363/839 (43%), Gaps = 101/839 (12%) Query: 764 IENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDEL 823 I N++ + + + RL + V+EDR +RK + L L E ++ S+ +QE +L Sbjct: 1865 IHNLQLRVKETSNENLRL---LHVIEDR----DRKVESL---LNEMKELDSKLHLQEVQL 1914 Query: 824 VNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNL--QISLSD-MQQHYNALV 880 + ++ ++ +++V E++ EN +L +K + ++Q L ++ S+ + Sbjct: 1915 MTKIEACIELEKIVG----ELKKENSDLSEKLEYFSCDHQELLQRVETSEGLNSDLEMHA 1970 Query: 881 EKANRTDLAESEST---KYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIE 937 +K++R D+ ++ + ++ + D+E+ L RI E K IE + +E Sbjct: 1971 DKSSREDIGDNVAKVNDSWKERFLDVENELSRIRSE--------KASIEHEALYLEADLE 2022 Query: 938 SAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMN--LELIDKHVQK 995 +K L + E + + LE +L + L ++ ++K L+ + + +++ Sbjct: 2023 VVQTEKLCLEKDNENKQKVIVCLEEELSVVTSERNQLRGELDTMSKKTTALDQLSEKMKE 2082 Query: 996 QQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTT 1055 + + + + ++ I A +K+K E + L+ S VS+ Sbjct: 2083 KTQELESHQSECLHCIQVAEAEVKEKTELLQTLS-----------SDVSELLKDKTHLQE 2131 Query: 1056 KLENMEEEMQRVS--KQLLDSK--QHNEELQILVREQDDQIKELKETKLTFEMNIPKT-E 1110 KL+++E++ Q +S K L+++ Q N+E ++LV+E + L E+ ++N+ K E Sbjct: 2132 KLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLSESDYE-KLNVSKALE 2190 Query: 1111 GMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEE---FIQERSVLQEQSAKLNTE 1167 ++ + + + ++++ +E+ I E+ +E+ + Sbjct: 2191 AALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKD 2250 Query: 1168 LQECYTKIIQLETLNTELTGHDVVNQE-QINQLKSKLEQLNTENDNLLSTVAELRS---S 1223 E + +Q+ N EL D N + ++ LK+++E++ + LRS + Sbjct: 2251 KVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKEN 2310 Query: 1224 ISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEET 1283 ++ + ++ +++EL K + + +K + E++++ ESK ++ +Q+ +E Sbjct: 2311 LTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKE---ESK--TAVEMLQNQLKELN 2365 Query: 1284 NKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIE-DEKVAFXXXXXXXX 1342 + + Q ++ E+ L E+ + N IE LR+ +E DEK Sbjct: 2366 EAVAAL---CGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKE 2422 Query: 1343 XXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKV 1402 R EN +E I N+E+A L+ + V +AK+ Sbjct: 2423 SEHHADLLKGRVENLE----RELEIARTNQEHAALEAENSKG---------EVETLKAKI 2469 Query: 1403 LELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAIL 1462 +T L + ++ +T R+++ EN+ +L + ++RI +L S IL Sbjct: 2470 EGMTQSLRGLELDV----------VTIRSEK-ENLTNELQKEQERISELEIINSSFENIL 2518 Query: 1463 RLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEM 1522 + K E + KE +++++ T+ LN++VA L+ E AK + Sbjct: 2519 QEKEQE-----KVQMKEKSSTAMEMLQ------TQLKELNERVAALHNDQEACKAKEQNL 2567 Query: 1523 QTALENQEIEIVTL---NDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNK 1578 + +E E+E L DE N ++++S + + + V + +DE++ N+ Sbjct: 2568 SSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQ 2626 Score = 71.3 bits (167), Expect = 2e-10 Identities = 200/1146 (17%), Positives = 446/1146 (38%), Gaps = 124/1146 (10%) Query: 58 QKCLENAALVSKRIKE----HRKATAELLGRPFVPGISESLANTLKQKEILMEKIKQYKE 113 Q+C++ A +++ +++ H AEL V E+ KQK E+ Q + Sbjct: 412 QECIQMKARLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQ 471 Query: 114 LSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIK-------EKDNALSVLQVKMK 166 + + + + +V HL +K + N ++ K Sbjct: 472 IKENELRRSMEEMKKENNLLKSHSEQKAREVCHLEAELKNIKQCLNQSQNFAEEMKAKNT 531 Query: 167 IMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFI 226 ET + DLQEKIN+++ N T +D ++ E Sbjct: 532 SQETMLRDLQEKINQQE------NSLTLEKLKLAVADLEKQRDCSQDLLKKREHHIEQLN 585 Query: 227 AMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXX 286 ++ + E + LL +E K L+E L + E+ KL ++E Sbjct: 586 DKLSKTEKESKALLSALELKKKEYEELKEEKTLFSCWK----SENEKLLTQMES------ 635 Query: 287 XXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIEL-LEHLNCQIRQTNKEL 345 K++++ + ++ E + +E+ E+L+ +IR + L Sbjct: 636 ---------EKENLQSKINHLETCLKTQQIKSHEYNERVRTLEMDRENLSVEIRNLHNVL 686 Query: 346 ENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKN 405 ++K + T+ A +K S + + M SQL+ + + + ++ N Sbjct: 687 DSKSVEVETQKLAYMELQQKAE--FSDQKHQKEIENMCLKTSQLTGQVEDLEHKLQLLSN 744 Query: 406 EIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSL 465 EI + Q L+ + ++ KD +D + L + Q M Sbjct: 745 EIMDKDRCYQDLHAEYESLRDLLKSKD------ASLVTNEDHQRSLLAFDQQPAMHHSFA 798 Query: 466 IHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKN 525 +G +E ++ + + Q + +++ ++ L+ + E Q+N ++ + Sbjct: 799 NIIGEQGSMPSERSECRLEADQSPKN---SAILQNRVDSLEFSLESQKQMNSDLQKQCEE 855 Query: 526 MIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHL 585 ++++K + L + ++ +F V+++++ I +L E+ VAE N + L Sbjct: 856 LVQIKGEIEENLMKAEQMHQSF--VAETSQRISKLQEDTSAHQNVVAETLSALENKEKEL 913 Query: 586 VDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLA 645 +++ V + E++ L K+ LLE D ++EL +L + + +++ Sbjct: 914 ------QLLNDKVETEQAEIQELK----KSNHLLE----DSLKELQLLSETLSLEKKEMS 959 Query: 646 DISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKED 705 I L ++ E++ + + KE+ + K++ Q + + +++E Sbjct: 960 SIISLNKREI----------EELTQENGTLKEINASLNQEKMNLIQKSESFANYIDEREK 1009 Query: 706 IMNKLQN-YIQENMDLTDKLEKM--SAEKISELLAKINHEEQSKIQTQFGIDAKIQERDL 762 +++L + Y QE + L + E+ + E +S+ K E+ SK ++ + E Sbjct: 1010 SISELSDQYKQEKLILLQRCEETGNAYEDLSQKY-KAAQEKNSK------LECLLNECTS 1062 Query: 763 YIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDE 822 EN ++EL + K + E + ++ ER + + +Q SE T ++ Sbjct: 1063 LCENRKNELEQLKEAFAK--EHQEFLTKLAFAEERNQNLMLELETVQQALRSEMTDNQNN 1120 Query: 823 LVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEK 882 + L +++++ ++ E ++QK+ LL+EN+ L + + N Sbjct: 1121 SKSEAGGL-------KQEIMTLKEEQNKMQKEVNDLLQENEQLMKVMKTKHECQNL---- 1169 Query: 883 ANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRD 942 ES + +++ ES + + Q + K+ ++ + Q+E+ +R+ Sbjct: 1170 ---------ESEPIRNSVKERESERNQCNFKPQMDLEVKEISLDSYNAQL-VQLEAMLRN 1219 Query: 943 KKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNM-NVEELNKMNLELIDKHVQKQQTQSP 1001 K++ ++ EK E L+ +LQ + ++E N+ +++ L+ + +++ P Sbjct: 1220 KELKLQESEKEKEC---LQHELQTIRGDLETSNLQDMQSQEISGLKDCEIDAEEKYISGP 1276 Query: 1002 DYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENME 1061 N+ L L+ ++ L + Q +V++ ++ T M Sbjct: 1277 HELSTSQNDNAHLQCSLQTTMNKLNELEKICEILQAEKYELVTELNDSRSECITATRKMA 1336 Query: 1062 EEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPM 1121 EE V K L + K N++ +L EL E E E +S + P+ Sbjct: 1337 EE---VGKLLNEVKILNDDSGLL-------HGELVEDIPGGEFGEQPNEQHPVS--LAPL 1384 Query: 1122 SDDANNVDXXXXXXXXXXXXLKVQEEEEFIQ-ERSVLQEQSAKLNTELQECYTKIIQLET 1180 + + ++QE+ +Q E +L +Q ++++++ E T + L+ Sbjct: 1385 DESNSYEHLTLSDKEVQMHFAELQEKFLSLQSEHKILHDQHCQMSSKMSELQTYVDSLKA 1444 Query: 1181 LNTELT 1186 N L+ Sbjct: 1445 ENLVLS 1450 Score = 71.3 bits (167), Expect = 2e-10 Identities = 141/730 (19%), Positives = 305/730 (41%), Gaps = 55/730 (7%) Query: 143 DVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXX 202 +V L I+E +L V ++ + + + +L ++I EK + +K + Sbjct: 2279 EVETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEE 2338 Query: 203 XXXXXXXXXEDTKQQMTKMQENFIAMEAEWKD--EKQRLLKDIE-SKDVRISSLEEANKL 259 E++K + +Q + Q ++K E S D I + Sbjct: 2339 KEQAEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIEEEHQLRNS 2398 Query: 260 LEAARFEISLEHSK---LAQELEQXXXXXXXXXXXXXXLAKQ-SIEPSCEEKTEIE---E 312 +E R + + K + Q+L++ L ++ I + +E +E Sbjct: 2399 IEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRVENLERELEIARTNQEHAALEAENS 2458 Query: 313 KGSLEI--ANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLI 370 KG +E A + +T+ + LE IR + L N+L + + ++ Sbjct: 2459 KGEVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTNELQKEQERISELEIINSSFENIL 2518 Query: 371 SRKSGRNTASKMKSPWSQLSSETLNQDTDKKI----NKNEIAKL-EMVIQSLNKDL-VDK 424 K K KS + +T ++ ++++ N E K E + S + L ++K Sbjct: 2519 QEKEQEKVQMKEKSSTAMEMLQTQLKELNERVAALHNDQEACKAKEQNLSSQVECLELEK 2578 Query: 425 EYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQ-HMEGPSLIHVGTNTED----VNEIA 479 ++ D + LI +++ Q+ + + + +D V++++ Sbjct: 2579 AQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEQLVSKLS 2638 Query: 480 KVQ--EQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKL 537 +V+ QL +E N E++++ V +L +K++ + + L D ++ + +++ +L+L Sbjct: 2639 QVEGEHQLWKEQNLELRNLTV-ELEQKIQVLQSKNASLQDTLEVLQSSYKNLEN--ELEL 2695 Query: 538 KQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESD 597 +M K + KV+ + L E+H ++QK AEL+EE + L + E Sbjct: 2696 TKMDK-MSFVEKVNKMTAKETELQREMHEMAQKTAELQEELSGEKNRLAGELQLLLEEIK 2754 Query: 598 VYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCS 657 K ++ L + LK L+ D V++ ++++ E + +L + + + Sbjct: 2755 SSKDQLKELTLENSELK--KSLDCMHKDQVEKEGKVREEIAEYQLRLHEAEKKHQALLLD 2812 Query: 658 EIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQEN 717 K +E Q + KE L + L++D L++ KE++ N L+ Q Sbjct: 2813 TNKQYEVEIQTYREKLTSKEECLSSQKLEIDL---------LKSSKEELNNSLKATTQIL 2863 Query: 718 MDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSR 777 +L K KM K L K N Q K++ +++E E ++ ELS+ ++ Sbjct: 2864 EEL--KKTKMDNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEK---EILQKELSQLQAA 2918 Query: 778 ICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNR-LAVLMDHDRV 836 + +++ VM+ K D+L + ++E ++ E T + DE +++ ++L+ H+++ Sbjct: 2919 QEK-QKTGTVMDT-------KVDELTTEIKELKETLEEKTKEADEYLDKYCSLLISHEKL 2970 Query: 837 VE-KQLLEIE 845 + K++LE + Sbjct: 2971 EKAKEMLETQ 2980 Score = 37.9 bits (84), Expect = 2.3 Identities = 90/601 (14%), Positives = 229/601 (38%), Gaps = 14/601 (2%) Query: 958 TQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNAL 1017 T+ ++QE + ++ L ++ + L+ ++ +QKQ+ + + + N + + N Sbjct: 14 TRALQKIQELEGQLDKLKKEKQQ-RQFQLDSLEAALQKQKQKVENEKTEGTN-LKRENQR 71 Query: 1018 LKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQH 1077 L + E + QKI++ S V+ E +L ++E +E+E++R +L S+Q Sbjct: 72 LMEICESLEKTKQKISHELQVKESQVNFQEGQLNSGKKQIEKLEQELKRCKSELERSQQA 131 Query: 1078 NEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXX 1137 + + + + +++ T LT ++ + ++ ++ Sbjct: 132 AQSADVSLNPCNTP-QKIFTTPLTPSQYYSGSKYEDLKEKYNKEVEERKRLEAEVKALQA 190 Query: 1138 XXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKI---IQLETLNTELTGHDVVNQE 1194 + + ++ + Q S+ + + ++ + + Q + + + ++ Sbjct: 191 KKASQTLPQATMNHRDIARHQASSSVFSWQQEKTPSHLSSNSQRTPIRRDFSASYFSGEQ 250 Query: 1195 QINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTE 1254 ++ +S L Q+ + N S+ + SS +DQ + EL + + + E Q E Sbjct: 251 EVTPSRSTL-QIGKRDAN--SSFFD-NSSSPHLLDQLKAQNQEL-RNKINELELRLQGHE 305 Query: 1255 HELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYA 1314 E++ Q++ F+ QL + ++E +++ + L++K Sbjct: 306 KEMKGQVNKFQELQLQLEKAKVELIEKEKVLNKCRDELVRTTAQYDQASTKYTALEQKLK 365 Query: 1315 DVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEEN 1374 + + R E + + + Q+ Q Q + +E Sbjct: 366 KLTEDLSCQRQNAESARCSLEQKIKEKEKEFQEELSRQQRSFQTLDQECIQMKARLTQEL 425 Query: 1375 AQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEF 1434 Q K E + E +L + + +Q + L + +E Sbjct: 426 QQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQKL-CRAEQAFQASQIKENELRRSMEEM 484 Query: 1435 ENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVK 1494 + L + ++ E+EL ++ ++++ N E M K + ++ +L K Sbjct: 485 KKENNLLKSHSEQKAREVCHLEAELKNIKQCLNQSQNFAEEM-KAKNTSQETMLRDLQEK 543 Query: 1495 ITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKI 1554 I + + + + +L A+ + + + Q L+ +E I LND+++ + +A S + Sbjct: 544 INQQEN-SLTLEKLKLAVADLEKQRDCSQDLLKKREHHIEQLNDKLSKTEKESKALLSAL 602 Query: 1555 Q 1555 + Sbjct: 603 E 603 >UniRef50_UPI0001509DA0 Cluster: hypothetical protein TTHERM_00535450; n=1; Tetrahymena thermophila SB210|Rep: hypothetical protein TTHERM_00535450 - Tetrahymena thermophila SB210 Length = 1469 Score = 124 bits (300), Expect = 2e-26 Identities = 189/898 (21%), Positives = 401/898 (44%), Gaps = 82/898 (9%) Query: 488 ELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNF 547 +L + +D+ +K ++ E Q+ L +EID + ++ ++ K+K ++ TI+N Sbjct: 118 QLQSQQEDLKIK-YASDIQQYENQMVSLKNEIDRLSNQQGQINQSNNQKVKNLESTIENK 176 Query: 548 SK-VSDSNKEIV---RLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMI 603 + +++ ++I+ + E+ L+Q+ + + + + + I+S + ++ Sbjct: 177 AAIINELQRQIIDKNQYQEQQIILAQQESSFSKNQSQFLDPQILIIKDQEIQS-IKMQLS 235 Query: 604 EMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVH 663 EM++ +++A S E + F+ + +LQ++ ++ ++ I++ S Q+ S +KS Sbjct: 236 EMQSKLNQQIQAFSSQEEENFNQKKANRLLQEENKKLNLQVQQITK-NSSQIESRLKS-- 292 Query: 664 LEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDK 723 E + S K +L V E LK K++ + L+N ++ KLQ QE M LT++ Sbjct: 293 --ELESSQSILKLQLNEVQEKLKQLKKKHKHKKQLLKNKIKEYEIKLQEMEQEAMILTEQ 350 Query: 724 LEKMSAEKISELLAKINHEEQSKIQTQF-------GIDAKIQERDLYI-ENIESELSKY- 774 ++ +H E Q Q ++A ++E+ + + +++ + K Sbjct: 351 HRNDKRNLTEQIQITKDHYEYLLQQQQTDMANTLQNMNANLEEQKIKLRQDLTEQFEKQS 410 Query: 775 KSRICRLEESIAVMEDRRYSLERKAD-QLGSY-LQEKQ--------KAYSEYTIQEDELV 824 K+ + ++ I ++ R Y +++K D Q+ + +Q KQ ++ I+ ++L Sbjct: 411 KANKQQYDQEIQKLKKREYEIQKKFDEQMHDFVIQNKQIQNNFFQNNDFALVKIENEKLK 470 Query: 825 NRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKAN 884 LA + ++ L + + L +KN L E+ NL+ L + Y + ++ Sbjct: 471 QELASVKTENQFA---LNQQNYTVNNLTEKNDALEEQIVNLKKQLGKQEIEYEKMKKQFE 527 Query: 885 RTDL-AESESTKYQTQLRDLES--NLKRITHEHQTLI------VQKKKEIEDLEIEFNTQ 935 + +E+ S ++ RD + N KR ++ L+ +QKK EI+ E + Sbjct: 528 SLKIDSETLSQRFNILQRDKDQAVNEKRQIQKNFDLLEKERNDIQKKLEIKKEEYQNQHI 587 Query: 936 IESAIRDKKVLNEKYEKNIEYVT-QLEAQLQEYKNNIENLNMNVEELN---KMNLELID- 990 + + +K + E+ NI+ T Q++ L N+ + LNM +E+ N K+++EL + Sbjct: 588 LYERVYEKLNITEQELSNIKNETEQIQTSLFSQINDFKILNMKLEKENEQMKISIELFND 647 Query: 991 -KHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESK 1049 K K+Q QS +NE KL L++Q + + I+ Q+ + +Y+ + Sbjct: 648 YKKESKEQIQSLRDENSKVNE--KLVQLIQQNNSNTQEKSSAISQLQIE----LKNYQIQ 701 Query: 1050 LAQFTTKLENMEEEMQ------RVSKQLLDS-KQHNEELQILVREQDDQIK----ELKET 1098 L K+E ++EE+Q V K+ + S ++ + +L+ +R++D+QI +L+ Sbjct: 702 LEDKVQKIEKLKEEVQDFKINEEVRKRQIQSLEEQSTDLKQTIRQKDEQINNAQHDLEVY 761 Query: 1099 KLTFEMNIPKTEGMIISSTIEPMSDDANN-------VDXXXXXXXXXXXXLKVQEEEEFI 1151 K F++ K + I + AN + LK E+ + Sbjct: 762 KQRFQICKQKLKEAFIQILDSIRLEQANKQLLLKLFEESLKIQFTRSICSLKDNYEDSIL 821 Query: 1152 QERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTEND 1211 + Q + L E + Q++ L ++T N + Q ++Q+ E Sbjct: 822 AIQMYTQGVLSDLKATQNEKSNLVEQIKQLKQQITEQTKQNTARQKQESENMQQIQ-EKS 880 Query: 1212 NLLSTVAELRSSISSAVDQRGFEIAELWK--QHLAQREADFQKTEHELRVQLSAFESKYE 1269 N LS ++ IS + + E+ K + + + + D +KT+ E +S E Sbjct: 881 NQLS--KNMKQEISELKKKNNSLLLEIQKSNEKIIEYQLDQKKTKSEKDRMQETIDSLCE 938 Query: 1270 QLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQ--IEILRS 1325 + + +Q E+T KI S+ N+L+ E L+ L ++ ++ + I++ RS Sbjct: 939 E-IKHIQQDNNEKTEKINHWRSQESMSNQLE--MERLQKLCQQELNIYQEKIIQMQRS 993 Score = 122 bits (294), Expect = 8e-26 Identities = 191/969 (19%), Positives = 424/969 (43%), Gaps = 73/969 (7%) Query: 638 DEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIK 697 DE+ D L + D V IK + E D + ++L++ +K D + L Sbjct: 59 DELIDTLKK-DKTSVDYVQVRIKEIIQECMNDDKESVIEKLSIQYSKIKSDYQLLDEAFN 117 Query: 698 DLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKI 757 L++ +ED+ K + IQ+ + L K +++S +IN K++ +++ I Sbjct: 118 QLQSQQEDLKIKYASDIQQYENQMVSL-KNEIDRLSNQQGQINQSNNQKVKN---LESTI 173 Query: 758 QERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYT 817 + + I ++ ++ + +E ++ + S + Q +L + + Sbjct: 174 ENKAAIINELQRQIIDKN----QYQEQQIILAQQESSFSKNQSQ---FLDPQILIIKDQE 226 Query: 818 IQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYN 877 IQ ++ +L+ + + E EN +K N++L EEN+ L + + + ++ + Sbjct: 227 IQSIKM--QLSEMQSKLNQQIQAFSSQEEENFNQKKANRLLQEENKKLNLQVQQITKN-S 283 Query: 878 ALVEKANRTDLAESESTKYQTQLRDLESNLKRIT--HEHQTLIVQKK-KEIE----DLEI 930 + +E +++L S+S + QL +++ LK++ H+H+ +++ K KE E ++E Sbjct: 284 SQIESRLKSELESSQSI-LKLQLNEVQEKLKQLKKKHKHKKQLLKNKIKEYEIKLQEMEQ 342 Query: 931 EFNTQIESAIRDKKVLNEKYEKNIE-YVTQLEAQLQEYKNNIENLNMNVEELNKMNLELI 989 E E DK+ L E+ + + Y L+ Q + N ++N+N N+EE ++L Sbjct: 343 EAMILTEQHRNDKRNLTEQIQITKDHYEYLLQQQQTDMANTLQNMNANLEE---QKIKLR 399 Query: 990 DKHVQKQQTQSPDYTEQYINEINKLN----ALLKQKDEEI---IALNQKINN--AQVSYM 1040 ++ + QS +QY EI KL + K+ DE++ + N++I N Q + Sbjct: 400 QDLTEQFEKQSKANKQQYDQEIQKLKKREYEIQKKFDEQMHDFVIQNKQIQNNFFQNNDF 459 Query: 1041 SMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQI-KELKETK 1099 ++V KL Q +L +++ E Q Q + + E + EQ + K+L + + Sbjct: 460 ALVKIENEKLKQ---ELASVKTENQFALNQQNYTVNNLTEKNDALEEQIVNLKKQLGKQE 516 Query: 1100 LTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQ-ERSVLQ 1158 + +E + E + I S E +S N + ++Q+ + ++ ER+ +Q Sbjct: 517 IEYEKMKKQFESLKIDS--ETLSQRFNILQRDKDQAVNEKR--QIQKNFDLLEKERNDIQ 572 Query: 1159 EQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVA 1218 + KL + +E + I E + +L + +++++ +K++ EQ+ T + ++ Sbjct: 573 K---KLEIKKEEYQNQHILYERVYEKLN----ITEQELSNIKNETEQIQTSLFSQINDFK 625 Query: 1219 ELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSS 1278 L + +Q I EL+ + + + Q LR + S K QL+ S+ Sbjct: 626 ILNMKLEKENEQMKISI-ELFNDYKKESKEQIQ----SLRDENSKVNEKLVQLIQQNNSN 680 Query: 1279 TQEETNKIVTME-QVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEI---EDEKVAF 1334 TQE+++ I ++ ++ + Q +L+DK + + L+E+ D E+ + +I E++ Sbjct: 681 TQEKSSAISQLQIELKNYQIQLEDKVQKIEKLKEEVQDFKINEEVRKRQIQSLEEQSTDL 740 Query: 1335 XXXXXXXXXXXXXXXXDLRTENQSY---KQMQEQSILNINEENAQLKKSSXXXXXXXXXX 1391 DL Q + KQ +++ + I ++ +L++++ Sbjct: 741 KQTIRQKDEQINNAQHDLEVYKQRFQICKQKLKEAFIQI-LDSIRLEQANKQLLLKLFEE 799 Query: 1392 XXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDL 1451 ++ + + L E I T L +E N+ +Q+ + +++I + Sbjct: 800 SLKIQFTRS-ICSLKDNYEDSILAIQMYTQGVLSDLKATQNEKSNLVEQIKQLKQQITEQ 858 Query: 1452 TYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKA 1511 T + + + E+ N + +K +++ + + +E++ ++ SL ++ + N+ Sbjct: 859 TKQNTAR------QKQESENMQQIQEKSNQLSK-NMKQEISELKKKNNSLLLEIQKSNEK 911 Query: 1512 LEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQ 1571 + E + ++ + + I +L +EI ++Q + KI S S + Q E+ Sbjct: 912 IIEYQLDQKKTKSEKDRMQETIDSLCEEIKHIQQDNNEKTEKINHWRSQESMSNQLEMER 971 Query: 1572 LDNTMNKEL 1580 L +EL Sbjct: 972 LQKLCQQEL 980 Score = 52.4 bits (120), Expect = 1e-04 Identities = 130/693 (18%), Positives = 298/693 (43%), Gaps = 80/693 (11%) Query: 153 EKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXE 212 E +++ S+L++++ ++ + L++K K Q+++ K K Sbjct: 293 ELESSQSILKLQLNEVQEKLKQLKKKHKHKKQLLKNKIKEYEIKLQEMEQEAMILTEQHR 352 Query: 213 DTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHS 272 + K+ +T+ + KD + LL+ + D+ ++L+ N LE + ++ + Sbjct: 353 NDKRNLTEQIQIT-------KDHYEYLLQQ-QQTDMA-NTLQNMNANLEEQKIKLRQD-- 401 Query: 273 KLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLE 332 L ++ E+ Q I+ + + EI++K ++ + K+I+ Sbjct: 402 -LTEQFEKQSKANKQQYD-------QEIQKLKKREYEIQKKFDEQMHDFVIQNKQIQNNF 453 Query: 333 HLN---CQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQL 389 N ++ N++L+ +LA++ TE++ + ++ K+ ++ + QL Sbjct: 454 FQNNDFALVKIENEKLKQELASVKTENQFALNQQNYTVNNLTEKNDA-LEEQIVNLKKQL 512 Query: 390 SSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLI 449 + + + KK ++ E + Q N DK+ ++EK ++ + Sbjct: 513 GKQEIEYEKMKKQFESLKIDSETLSQRFNILQRDKDQAVNEKRQIQKNFDLLEKERNDIQ 572 Query: 450 AQLQLEHQQHMEGPSLIH-----VGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDL-IE 503 +L+++ +++ L + ++++ I EQ++ L +I D + ++ +E Sbjct: 573 KKLEIKKEEYQNQHILYERVYEKLNITEQELSNIKNETEQIQTSLFSQINDFKILNMKLE 632 Query: 504 K---------------LKSAEEQITQLNDEIDAANKNMIKV----KSNHKLK---LKQMQ 541 K K ++EQI L DE N+ ++++ SN + K + Q+Q Sbjct: 633 KENEQMKISIELFNDYKKESKEQIQSLRDENSKVNEKLVQLIQQNNSNTQEKSSAISQLQ 692 Query: 542 KTIDNFS-KVSDSNKEIVRLTEELHHL-------SQKVAELEEEKGNLQLHLVDYD---S 590 + N+ ++ D ++I +L EE+ +++ LEE+ +L+ + D + Sbjct: 693 IELKNYQIQLEDKVQKIEKLKEEVQDFKINEEVRKRQIQSLEEQSTDLKQTIRQKDEQIN 752 Query: 591 GRMIESDVYKKMIEMENLAETRLKA--ISLLESQKFDLVQELHILQQKYDEVEDKLADIS 648 + +VYK+ + + + +LK I +L+S + + + +L+ + ++ + Sbjct: 753 NAQHDLEVYKQRFQ---ICKQKLKEAFIQILDSIRLEQANKQLLLKLFEESLKIQFTRSI 809 Query: 649 QLQSDQVCSEIKSVHLEEQ--IDALSASKKELALVIENLKLDKEQL-YGTIKDLENDKED 705 D I ++ + Q + L A++ E + ++E +K K+Q+ T ++ K++ Sbjct: 810 CSLKDNYEDSILAIQMYTQGVLSDLKATQNEKSNLVEQIKQLKQQITEQTKQNTARQKQE 869 Query: 706 IMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIE 765 N Q IQE +++L K ++ISEL K N+ +IQ + KI E L + Sbjct: 870 SENMQQ--IQEK---SNQLSKNMKQEISELKKK-NNSLLLEIQKS---NEKIIEYQLDQK 920 Query: 766 NIESELSKYKSRICRLEESIA-VMEDRRYSLER 797 +SE + + I L E I + +D E+ Sbjct: 921 KTKSEKDRMQETIDSLCEEIKHIQQDNNEKTEK 953 >UniRef50_UPI00006CC401 Cluster: hypothetical protein TTHERM_00133600; n=1; Tetrahymena thermophila SB210|Rep: hypothetical protein TTHERM_00133600 - Tetrahymena thermophila SB210 Length = 1066 Score = 124 bits (300), Expect = 2e-26 Identities = 221/1143 (19%), Positives = 497/1143 (43%), Gaps = 114/1143 (9%) Query: 475 VNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHK 534 +N + K QL +E D ++ V L EK+ S E QL ++ + ++ + Sbjct: 20 LNSLTKSYNQLVKEKKDI--EIFVDTLREKVHSLEST-KQLYEQA----QQQLQTQKQSI 72 Query: 535 LKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMI 594 L++ Q+ I ++ ++ + +++++ +E +++ Q++ +++ L + ++D Sbjct: 73 QDLQKKQEAI--LAQKNEQDNKLIKVMKEKYNIQQELEKIKSSNEELSVTMIDEMEEMKK 130 Query: 595 ESDV-YKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSD 653 + ++ +++ +++ A TR + + L + + L+++ Q +Y+E+ + L +Q S Sbjct: 131 KMNITFQEQSKIQQEA-TRQQILQLQQLSQQKLIEK----QMEYEEICNLLEKTNQELSY 185 Query: 654 Q--VCSEI--KSVHLEEQIDALSASKKELALVIENLK--LD--KEQLYGTIKDLENDKED 705 Q +C E+ K + E+I LS E +E LK LD +E+ + K++ Sbjct: 186 QQEMCKELEKKLEYSAEKIKELSNKLAEEKANVEALKKQLDEYREKYQKNLASQNQLKDE 245 Query: 706 IMN---KLQNYIQENMDLTDKLEKMSAEKIS--ELLAKINHEEQSKIQTQFGIDAKIQER 760 ++N K++ + +TD+ + +S E + L+K+ E ++ ++ Q + + E Sbjct: 246 LLNAQAKIKQLTTQLQQITDQQQLISGESSNYRSQLSKMEEEHRNLVEIQKFLSNENSEL 305 Query: 761 DLYIENIESELSKYKSRICRLEESIAVMED--RRYSLERKADQLGSYLQEKQKAYSEYTI 818 N + ++ + +++ +++I + + +LE+ D + + K S+ Sbjct: 306 SNQSLNFKKQIEQLQNQQQEFKKAIESKDQAIEKLNLEKSQDLVKLETNYRSKIDSQMK- 364 Query: 819 QEDELVNRL-AVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYN 877 D+L NRL V M++ + ++K L E+ ++L ++ Q L E Q+ ++ Q++ N Sbjct: 365 DIDQLTNRLNEVEMNYAKTLDK-LESSENTCRDLLQQIQNLQNELQSQKMIA---QENIN 420 Query: 878 ALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIE 937 L +K L E E Q + E NL I+ + Q Q I+DL E N ++ Sbjct: 421 QLTQK-----LKEKEEKLAAVQ-KKYEQNLFEISQKEQ----QNNSYIQDLNKEVNN-LK 469 Query: 938 SAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQ 997 + + K NE + + + LE +L K +++ L ++ K +E+ + +QK+Q Sbjct: 470 NIVTTKSRENEILQNQNQSIVVLEEKL---KISLQQLQQGAQKEEKYRIEIEEIAMQKEQ 526 Query: 998 TQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKL 1057 + + N IN+++ LKQ EEI +L KI + Y + + + K +++ Sbjct: 527 YEK--LMHETTNRINQMSMQLKQCKEEISSLETKIEQDRKQYNVNLEEEKQKNEFANSQI 584 Query: 1058 ENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISST 1117 + ++ Q++ +++L+++ Q +++ ++Q++ K+ ++ MN E S Sbjct: 585 QELQFLCQKLKEEILENENVLSYTQQQLQQTEEQLQSAKD-QINI-MNQAMFERESYHSE 642 Query: 1118 IEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQ 1177 + ++N LK+ E+E ++ + LQ + ++ + ++ Sbjct: 643 VLNQQQNSN----------LELNTLKL-EKENYLNLVTELQTTNQQIKQDNSYLKSENDN 691 Query: 1178 LETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAE 1237 L+ EL + NQE + Q L+Q N+NL L+ +D E Sbjct: 692 LKKQFEELLQN---NQENLYQKDELLQQ----NENLSQQYKVLKQENHLILDNIQQIKQE 744 Query: 1238 LWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQN 1297 L ++ Q + D + +++ + S F + L V ++E + T Q + +QN Sbjct: 745 LESKNKIQSD-DLRNANNQVNIAFSTFSQLFSHLALVVGQQVRDE-QLLDTFNQSSQIQN 802 Query: 1298 KLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQ 1357 L NL + +N E + ++ L+ + Sbjct: 803 TLDQ-----LNLSSNFESKLN----FMKESMTQFLSTIKNMSDERLQNNQVSLQLKQQVA 853 Query: 1358 SYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIY 1417 +Q+ + + E QL+ ++N AK+ + +Q + S Sbjct: 854 QLQQINQNQLEQSQSERQQLQSQ----IQELEQSNQQLNQEIAKLKQQANQC-ISPSNQN 908 Query: 1418 QKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQ 1477 K + Y + Q ++++ + L++ +++++DL Y+ E ++K ++ N Q Sbjct: 909 SKDNFYNMNYEQLENDYKISQSILLDQKQQLKDLKYDLEQ-----KIKKYQEENQVFAQQ 963 Query: 1478 KESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLN 1537 + ++V L+E + SL+K+ E L N+ ++ QE Sbjct: 964 NKELQDKVSLLE------AQKTSLSKEYGEQQNCL-------NDCFDKIQYQE------- 1003 Query: 1538 DEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDLAMYM-L 1596 EI NLQ ++ S + + + +E+ N MN E++++ ++ ++A + L Sbjct: 1004 QEIQNLQQLLEESDFENVLLKKIQQNNELNVEEESRNKMNSEIIESAKQSISNIARHFNL 1063 Query: 1597 HQR 1599 +Q+ Sbjct: 1064 NQK 1066 Score = 113 bits (271), Expect = 5e-23 Identities = 171/870 (19%), Positives = 373/870 (42%), Gaps = 58/870 (6%) Query: 474 DVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNH 533 + EI + E+ QEL+ + K+L +KL+ + E+I +L++++ N+ +K Sbjct: 168 EYEEICNLLEKTNQELS--YQQEMCKELEKKLEYSAEKIKELSNKLAEEKANVEALKKQL 225 Query: 534 KLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRM 593 ++ QK + + +++ D E++ ++ L+ ++ ++ +++ + +Y S Sbjct: 226 DEYREKYQKNLASQNQLKD---ELLNAQAKIKQLTTQLQQITDQQQLISGESSNYRSQLS 282 Query: 594 IESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDE-VEDKLADISQLQS 652 + ++ ++E++ +S +++L QQ++ + +E K I +L Sbjct: 283 KMEEEHRNLVEIQKFLSNENSELSNQSLNFKKQIEQLQNQQQEFKKAIESKDQAIEKLNL 342 Query: 653 DQVCSEIK-SVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNK-- 709 ++ +K + +ID+ +L + ++++ + ++ EN D++ + Sbjct: 343 EKSQDLVKLETNYRSKIDSQMKDIDQLTNRLNEVEMNYAKTLDKLESSENTCRDLLQQIQ 402 Query: 710 -LQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIE 768 LQN +Q + + +K+ E K+ ++ Q F I K Q+ + YI+++ Sbjct: 403 NLQNELQSQKMIAQENINQLTQKLKEKEEKLAAVQKKYEQNLFEISQKEQQNNSYIQDLN 462 Query: 769 SELSKYKSRICRLEESIAVMEDRRYS---LERKAD------QLGSYLQEKQKA-YSEYTI 818 E++ K+ + +++++ S LE K Q G+ +EK + E + Sbjct: 463 KEVNNLKNIVTTKSRENEILQNQNQSIVVLEEKLKISLQQLQQGAQKEEKYRIEIEEIAM 522 Query: 819 QED-------ELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSD 871 Q++ E NR+ + + ++++ +E + ++ +K+ + LEE + + Sbjct: 523 QKEQYEKLMHETTNRINQMSMQLKQCKEEISSLETKIEQDRKQYNVNLEEEKQKNEFANS 582 Query: 872 MQQHYNALVEKANRTDLAESESTKY-QTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEI 930 Q L +K L Y Q QL+ E L+ + ++ Q E E Sbjct: 583 QIQELQFLCQKLKEEILENENVLSYTQQQLQQTEEQLQS-AKDQINIMNQAMFERESYHS 641 Query: 931 EFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELID 990 E Q +++ + L + E + VT+L+ Q+ K + L + L K EL+ Sbjct: 642 EVLNQQQNSNLELNTLKLEKENYLNLVTELQTTNQQIKQDNSYLKSENDNLKKQFEELLQ 701 Query: 991 KHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVS-DYESK 1049 + Q+ Q + +Q N +++ +LKQ++ I+ Q+I S + S D + Sbjct: 702 NN-QENLYQKDELLQQNEN-LSQQYKVLKQENHLILDNIQQIKQELESKNKIQSDDLRNA 759 Query: 1050 LAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKE-LKETKLT--FE--M 1104 Q + ++ L+ +Q +E + Q QI+ L + L+ FE + Sbjct: 760 NNQVNIAFSTFSQLFSHLA--LVVGQQVRDEQLLDTFNQSSQIQNTLDQLNLSSNFESKL 817 Query: 1105 NIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKL 1164 N K STI+ MSD+ + +Q +++ Q + + Q Q + Sbjct: 818 NFMKESMTQFLSTIKNMSDE-----------RLQNNQVSLQLKQQVAQLQQINQNQLEQS 866 Query: 1165 NTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQL---NTENDNLLSTVAELR 1221 +E Q+ ++I +LE N +L ++Q NQ S Q N N N + + Sbjct: 867 QSERQQLQSQIQELEQSNQQLNQEIAKLKQQANQCISPSNQNSKDNFYNMNYEQLENDYK 926 Query: 1222 SSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQE 1281 S S +DQ+ ++ +L K L Q+ +Q+ Q + K LL++ ++S + Sbjct: 927 ISQSILLDQKQ-QLKDL-KYDLEQKIKKYQEENQVFAQQNKELQDKV-SLLEAQKTSLSK 983 Query: 1282 ETNKIVTMEQVTSLQNKLQDKEEHLRNLQE 1311 E + + +K+Q +E+ ++NLQ+ Sbjct: 984 EYGE--QQNCLNDCFDKIQYQEQEIQNLQQ 1011 Score = 99 bits (238), Expect = 5e-19 Identities = 143/745 (19%), Positives = 323/745 (43%), Gaps = 57/745 (7%) Query: 860 EENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIV 919 E+ + +Q L+ + + YN LV++ + D+ T + ++ LES K++ + Q + Sbjct: 11 EDIKAVQNQLNSLTKSYNQLVKE--KKDIEIFVDT-LREKVHSLEST-KQLYEQAQQQLQ 66 Query: 920 QKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMN-V 978 +K+ I+DL+ + E+ + K + K K ++ ++ +L++ K++ E L++ + Sbjct: 67 TQKQSIQDLQ----KKQEAILAQKNEQDNKLIKVMKEKYNIQQELEKIKSSNEELSVTMI 122 Query: 979 EELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNA---LLKQKD-EEIIALNQKINN 1034 +E+ +M ++ + Q+Q + T Q I ++ +L+ + KQ + EEI L +K N Sbjct: 123 DEMEEMKKKM-NITFQEQSKIQQEATRQQILQLQQLSQQKLIEKQMEYEEICNLLEKTNQ 181 Query: 1035 AQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKE 1094 M + E KL K++ + ++ + K+ +E + ++ + Sbjct: 182 ELSYQQEMCKELEKKLEYSAEKIKELSNKLAEEKANVEALKKQLDEYREKYQKNLASQNQ 241 Query: 1095 LKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQER 1154 LK+ L + I + +++ ++ ++D + ++ +E ++ + Sbjct: 242 LKDELLNAQAKIKQ-----LTTQLQQITDQQQLISGESSNYRSQLSKME-EEHRNLVEIQ 295 Query: 1155 SVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLL 1214 L ++++L+ + +I QL+ E ++ I +E+LN E L Sbjct: 296 KFLSNENSELSNQSLNFKKQIEQLQNQQQEF-------KKAIESKDQAIEKLNLEKSQDL 348 Query: 1215 STVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDS 1274 +L ++ S +D + +I +L + L + E ++ KT +L + E+ LL Sbjct: 349 ---VKLETNYRSKIDSQMKDIDQLTNR-LNEVEMNYAKTLDKLE----SSENTCRDLLQQ 400 Query: 1275 VQSSTQE-ETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVA 1333 +Q+ E ++ K++ E + L KL++KEE L +Q+KY N EI S+ E + + Sbjct: 401 IQNLQNELQSQKMIAQENINQLTQKLKEKEEKLAAVQKKYEQ--NLFEI--SQKEQQNNS 456 Query: 1334 FXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEE---NAQLKKSSXXXXXXXXX 1390 + EN+ Q Q QSI+ + E+ + Q + Sbjct: 457 YIQDLNKEVNNLKNIVTTKSRENE-ILQNQNQSIVVLEEKLKISLQQLQQGAQKEEKYRI 515 Query: 1391 XXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQL---VEYEKR 1447 + + + +L H+ + +++ + + ++ + E R+Q +E EK+ Sbjct: 516 EIEEIAMQKEQYEKLMHETTNRINQMSMQLKQCKEEISSLETKIEQDRKQYNVNLEEEKQ 575 Query: 1448 IEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAE 1507 + + EL L K+ E E ++ E+ + + ++L + S Q+ Sbjct: 576 KNEFANSQIQELQFLCQKLKE-----EILENENVLSYTQ--QQLQQTEEQLQSAKDQINI 628 Query: 1508 LNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMV---RASSSKIQKHVSFASDT 1564 +N+A+ E + +E+ +N +E+ TL E N N+V + ++ +I++ S+ Sbjct: 629 MNQAMFERESYHSEVLNQQQNSNLELNTLKLEKENYLNLVTELQTTNQQIKQDNSYLKSE 688 Query: 1565 KQGRDEQLDNTMNKELLDAVPRAEL 1589 +Q + + + + EL Sbjct: 689 NDNLKKQFEELLQNNQENLYQKDEL 713 Score = 62.9 bits (146), Expect = 7e-08 Identities = 125/692 (18%), Positives = 268/692 (38%), Gaps = 54/692 (7%) Query: 92 ESLANTLKQKEILMEKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTI 151 + L N L + E+ K E S+ + +++ ++ L+ + Sbjct: 367 DQLTNRLNEVEMNYAKTLDKLESSENTCRDLLQQIQNLQNELQSQKMIAQENINQLTQKL 426 Query: 152 KEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXX 211 KEK+ L+ +Q K E + ++ +K + + I+ NK Sbjct: 427 KEKEEKLAAVQKKY---EQNLFEISQKEQQNNSYIQDLNKEVNNLKNIVTTKSRE----- 478 Query: 212 EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKD---VRISSLEEANKLLEAARFEIS 268 + + ++ + +E + K Q+L + + ++ + I + + E E + Sbjct: 479 ---NEILQNQNQSIVVLEEKLKISLQQLQQGAQKEEKYRIEIEEIAMQKEQYEKLMHETT 535 Query: 269 LEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKI 328 ++++ +L+Q KQ + EE+ + E + +I + L +K+ Sbjct: 536 NRINQMSMQLKQCKEEISSLETKIEQDRKQ-YNVNLEEEKQKNEFANSQIQELQFLCQKL 594 Query: 329 --ELLEHLNC------QIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRN--- 377 E+LE+ N Q++QT ++L++ + ++A+ S +++++ N Sbjct: 595 KEEILENENVLSYTQQQLQQTEEQLQSAKDQINIMNQAMFERESYHSEVLNQQQNSNLEL 654 Query: 378 -TASKMKSPWSQLSSE--TLNQDTD------KKINKNEIAKLEMVIQSLNKDLVDKEYVI 428 T K + L +E T NQ K N N + E ++Q+ ++L K+ ++ Sbjct: 655 NTLKLEKENYLNLVTELQTTNQQIKQDNSYLKSENDNLKKQFEELLQNNQENLYQKDELL 714 Query: 429 SEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQE 488 + + ++ +Q + +Q +E + I N++ Q Sbjct: 715 QQNENLSQQYKVLKQENHLILDNIQ-QIKQELESKNKIQSDDLRNANNQVNIAFSTFSQL 773 Query: 489 LNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNF- 547 + V + E+L Q +Q+ + +D N + SN + KL M++++ F Sbjct: 774 FSHLALVVGQQVRDEQLLDTFNQSSQIQNTLDQLN-----LSSNFESKLNFMKESMTQFL 828 Query: 548 SKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRM------IESDVYKK 601 S + + + E ++ + L Q+VA+L++ N QL + ++ +E + Sbjct: 829 STIKNMSDERLQNNQVSLQLKQQVAQLQQINQN-QLEQSQSERQQLQSQIQELEQSNQQL 887 Query: 602 MIEMENLAETRLKAISLLESQKFDLVQELHI--LQQKYDEVEDKLADISQLQSD-QVCSE 658 E+ L + + IS D ++ L+ Y + L D Q D + E Sbjct: 888 NQEIAKLKQQANQCISPSNQNSKDNFYNMNYEQLENDYKISQSILLDQKQQLKDLKYDLE 947 Query: 659 IKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENM 718 K +E+ + KEL + L+ K L + +N D +K+Q QE Sbjct: 948 QKIKKYQEENQVFAQQNKELQDKVSLLEAQKTSLSKEYGEQQNCLNDCFDKIQYQEQEIQ 1007 Query: 719 DLTDKLEKMSAEKISELLAKINHEEQSKIQTQ 750 +L LE+ E + LL KI + ++ + Sbjct: 1008 NLQQLLEESDFENV--LLKKIQQNNELNVEEE 1037 >UniRef50_UPI00006CAB41 Cluster: hypothetical protein TTHERM_00781040; n=1; Tetrahymena thermophila SB210|Rep: hypothetical protein TTHERM_00781040 - Tetrahymena thermophila SB210 Length = 2198 Score = 124 bits (300), Expect = 2e-26 Identities = 272/1421 (19%), Positives = 596/1421 (41%), Gaps = 119/1421 (8%) Query: 234 DEKQRLLKDIESKDVRISS-LEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXX 292 +E++R L +I+ ++ LEE E ++ +E +L +E +Q Sbjct: 451 EERERRLNEIQFVKEQVEKRLEETEIHYENVIHKLEIEIRRLQEENQQIRKEFLETKEQI 510 Query: 293 XX--LAKQSI-EPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKL 349 + + ++ + +E + E+ + A TE K++E + L I Q +ELE ++ Sbjct: 511 DFERINQNTLNDRKLQESQDTWERRLQQCA--TEWQKEVEQRDQL---ISQKQRELEAQI 565 Query: 350 ATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAK 409 + +K L K R + + LN++ +K K + Sbjct: 566 RISQQNERKKIEIQQKYEALEKEKEKREEEFDSILQEQKRKIQILNEEVTQK--KVALKS 623 Query: 410 LEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVG 469 ++ IQ +++L ++ + + + + + E+ Q ++ Sbjct: 624 AQISIQDAHEELAHRKNEGHVWNATEQQIKEKIALQKSRLQDCEEENAQLKRDKLALNEK 683 Query: 470 TNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKV 529 + + +++++ Q+++ + D IK VK +E + E Q +I+ + +V Sbjct: 684 ISILE-SKLSESQKEISKIQEDLIKQQQVK--LEVQLNQESQANNYRKQIETLRAQLHEV 740 Query: 530 KSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYD 589 ++ +K+K+ + N S++++S + I + E S K ++ +E NLQ + ++ Sbjct: 741 QN--AIKIKESAYAVAN-SELNESRELIQEMKLEALRASHKQQQIADENNNLQSSVREWQ 797 Query: 590 ------SGRMIESDVYKKMIE--MENLAETRLKAISLLESQKFDLVQELHILQQKYDEVE 641 ++ ES + +IE + + L I E+Q+ + +EL ++ ++ E Sbjct: 798 RRAEQQQSQLEESRQIRSIIEEQQKKKVDELLMVIKQRETQQSCIEEELKAIKLSWENAE 857 Query: 642 DKLADISQ-LQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLE 700 + + + LQ + E+ + + ++D+ +EL + L+ D Q +L Sbjct: 858 RAIQILEEKLQEKERAQELFADQAQRELDSQHDRIEELMRIQNKLENDLSQA-----NLF 912 Query: 701 NDKE-DIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQE 759 NDK + QN IQ + +L+++ E+ +++ I + +Q IQ Q AK E Sbjct: 913 NDKSIKEIELFQNQIQSLTQMNHELQQLIEEQQAKV---IQNTDQKTIQAQQ--HAKRME 967 Query: 760 RDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQ 819 + N E E + ++ LE + L+R+ + + + Q+ + + Sbjct: 968 LQQQLSNKEEECLNIQKQVIDLETQLEKQIRMFEDLQRENNLINLKYNDTQERLKQLQSE 1027 Query: 820 EDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNAL 879 +E N ++ + + +R + + ENK +Q + + E + + S++++ +A+ Sbjct: 1028 CEEYNNLISQIQEKERKISLANQNLVQENKRIQSVVEQITNELREQKQENSNLKECNDAI 1087 Query: 880 VEK-AN---RTDLAESESTKYQTQLRDLESNLKRITHE---HQTLIVQKKKEIEDLEIEF 932 EK AN D + + +Y LE ++ + E H T + K+E +E Sbjct: 1088 CEKQANIQRENDRIKEQLEQYVNANAKLEEKVENLILENDSHSTENLALKQERIQIEYRL 1147 Query: 933 N-TQIESA-IRDKKVL----NEKYEKNI----EYVTQLEAQL--QEYKNNIEN--LNMNV 978 + +Q +S + ++ +L NE+ + N E++ ++ QL Q++ + + N N V Sbjct: 1148 SLSQNQSEKLNERSILLARENEEMKLNAIQREEFIAAIQQQLIDQQHDSVLRNNLQNQEV 1207 Query: 979 EELNKMNLELIDKHVQ-KQQTQSPDYT--EQYINEINKLNALLKQKDEEIIAL---NQKI 1032 ++LNKM +L D+ KQQ S + +Q IN++N A L+ E+++ + N+++ Sbjct: 1208 DKLNKMIKQLKDELTSLKQQMNSSNQEREQQLINQLNSSQAELQDFQEKLLIIRKENKQL 1267 Query: 1033 NNAQVSYMSMVSDYESKLAQFTTKLEN---------MEEEMQRVSKQLLDSKQHNEELQI 1083 N+ + + + + SK Q T+LEN ++EE + S+Q+ D Q ++L+ Sbjct: 1268 NDIKGELQAQL-EVISKRNQ-ETQLENELLQKESTKLKEEKRNQSEQIRDLNQKCQKLEE 1325 Query: 1084 LVREQDDQIKELKETKLTF----EMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXX 1139 + D+++ LKE+ E + + E + S T + A +D Sbjct: 1326 REKNMIDELQVLKESFKNIHRDKESALLELETSLASGTAKEALKGAE-LDQVQSELKKVT 1384 Query: 1140 XXLKVQ-------------EEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELT 1186 L+++ E EE ++ +E+ KL E +I QL TEL Sbjct: 1385 RRLELESTENKKKIQQLQTENEELKKQTDQEREKLRKLEYEAPNQIERINQLYARVTELN 1444 Query: 1187 GHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHL-AQ 1245 Q + + L S EQL E + L + + + ++ + +I E K++L Sbjct: 1445 EQKSELQFKQDVLSSAHEQLKQEKELLQYQLDQAQKNVQMIQNSHKEQIEERDKKYLNLM 1504 Query: 1246 READFQKTE-HELRVQLSAFESKYEQLLDSVQSSTQE--ETN-KIVTM-EQVTSLQNKLQ 1300 + + + E EL++ S E + L + + QE E N K++ + +Q+ +LQ + Sbjct: 1505 KNLNLKDQEIQELKLLNSQIEKDAQTLKINTELKIQENQELNQKVLNLNDQIQALQEQAA 1564 Query: 1301 DKEEHLRNLQE-KYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSY 1359 +++++ E +Y ++ + SE D ++EN Sbjct: 1565 VTQQNIQQQNEVRYPSKSPSLKKI-SECIDSP-----NQEEYVQDPINKFASQKSENPK- 1617 Query: 1360 KQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDS-EIYQ 1418 KQ+ I N + K S V++ E ++ + + QLE + + + Q Sbjct: 1618 KQVSYSQISNPPSRKSS-KHSKNQINQDNNNDHYDVDNNENQLQDESEQLEFQGNLDNSQ 1676 Query: 1419 KTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKM-HENANHYETMQ 1477 K + + + NV ++ V Y K I +++ K SE L E+ +E ++ Sbjct: 1677 KEKSKRMERDDESQQQANVPKKSVSYSK-ISNISSRKSSENYQQSLNQGQEDDQEFEELE 1735 Query: 1478 KESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLN 1537 + + + + TE ++ + N E E+ ++ +++N++++ + N Sbjct: 1736 YLGNQKNSQREMSMKAEKTEEYNIIPSQEDFN---EFEIDFNSQKNKSIDNRDLQNIASN 1792 Query: 1538 DEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNK 1578 + ++ S ++ K + F S + +++ ++ +K Sbjct: 1793 KSLPKIK-----SQNQSSKQIPFESQVQSQQNQIIEELQDK 1828 Score = 119 bits (287), Expect = 6e-25 Identities = 222/1142 (19%), Positives = 514/1142 (45%), Gaps = 133/1142 (11%) Query: 483 EQLKQELNDEIKDVNVKDLIEKLKSAEEQI---TQLNDEIDAANKNMIKVK---SNHKLK 536 ++L +EL +E + +K + E LKSA E + + DE+D+ K++ + + K Sbjct: 228 QKLFEELREENNQLKMKLVSEPLKSARESVEISRKYEDELDSIQIKYDKIEKQLAKTEKK 287 Query: 537 LKQMQKTIDN-FSKVSDSNKEIVRLTEELHHLS---QKVAELEEEKGNLQLHLVDYDSGR 592 + + TI + + D KE+ L +EL +L Q + +++G +++++ Sbjct: 288 CQDRKATIKKLYFLLEDKEKEVESLMQELENLRVNFQNKFQESDQRGQ-SIYILEKQIAE 346 Query: 593 MIESDVYKKMIEMENLAETRLKAI--SLLESQKFDLVQELHILQQKYDEVEDKLADISQL 650 + + ++M+ N + L+ + S+LE+Q+ +Q ++ + + + Sbjct: 347 IQRQN--QEMVNSRNERKENLEELNRSILEAQQKYKIQ----CREDFPTTLMRWKSVRDF 400 Query: 651 QSDQVCSEIKSVHLEEQIDALSASKKELALVIE-NLKLDKEQLYGTIKDLE--NDKEDIM 707 +D++ +I S+ EE +D + EL +E NL L+ E+L + L+ ++E + Sbjct: 401 FTDRL--KILSMQKEEAVDEQEKLRDELQREVERNLTLE-ERLTNYLNQLKQMEERERRL 457 Query: 708 NKLQNYIQENMDLTDKLEKMSAEKI---SELLAKINHEEQSKIQTQFGIDAKIQERDLYI 764 N++Q +++E ++ + ++ E + E+ + EE +I+ +F ++ K Q + Sbjct: 458 NEIQ-FVKEQVEKRLEETEIHYENVIHKLEIEIRRLQEENQQIRKEF-LETKEQ---IDF 512 Query: 765 ENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELV 824 E I + +L+ES E R L++ A + ++++ + S+ ++ EL Sbjct: 513 ERINQNTLNDR----KLQESQDTWERR---LQQCATEWQKEVEQRDQLISQ---KQRELE 562 Query: 825 NRLAVLMDHDR----VVEK-QLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNAL 879 ++ + ++R + +K + LE E E +E ++ + IL E+ + +QI ++ Q AL Sbjct: 563 AQIRISQQNERKKIEIQQKYEALEKEKEKRE-EEFDSILQEQKRKIQILNEEVTQKKVAL 621 Query: 880 VEKANRTDLAESESTKYQTQLRDLESNLKRITHEH-QTLIVQKKKEIEDLEIEFNTQIES 938 K+ + + ++ + R E ++ T + + I +K ++D E E N Q++ Sbjct: 622 --KSAQISIQDAHE---ELAHRKNEGHVWNATEQQIKEKIALQKSRLQDCE-EENAQLK- 674 Query: 939 AIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQT 998 RDK LNEK ++ LE++L E + I + ++ + ++ LE + + + Q Sbjct: 675 --RDKLALNEK-------ISILESKLSESQKEISKIQEDLIKQQQVKLE-VQLNQESQAN 724 Query: 999 QSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSM------VSDYESKLAQ 1052 E +++++ +K K+ N ++N ++ M S + ++A Sbjct: 725 NYRKQIETLRAQLHEVQNAIKIKESAYAVANSELNESRELIQEMKLEALRASHKQQQIAD 784 Query: 1053 FTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGM 1112 L++ E QR ++Q + + +++ ++ EQ Q K++ E + + +T+ Sbjct: 785 ENNNLQSSVREWQRRAEQQQSQLEESRQIRSIIEEQ--QKKKVDELLMVIKQR--ETQQS 840 Query: 1113 IISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSA-KLNTELQEC 1171 I ++ + N + +Q EE +QE+ QE A + EL Sbjct: 841 CIEEELKAIKLSWENAERA------------IQILEEKLQEKERAQELFADQAQRELDSQ 888 Query: 1172 YTKIIQL----ETLNTELTGHDVVNQEQINQL---KSKLEQLNTENDNLLSTVAELRSSI 1224 + +I +L L +L+ ++ N + I ++ +++++ L N L + E ++ + Sbjct: 889 HDRIEELMRIQNKLENDLSQANLFNDKSIKEIELFQNQIQSLTQMNHELQQLIEEQQAKV 948 Query: 1225 SSAVDQRGFEIAELWK-----QHLAQREAD---FQK----TEHELRVQLSAFE--SKYEQ 1270 DQ+ + + K Q L+ +E + QK E +L Q+ FE + Sbjct: 949 IQNTDQKTIQAQQHAKRMELQQQLSNKEEECLNIQKQVIDLETQLEKQIRMFEDLQRENN 1008 Query: 1271 LLDSVQSSTQEETNKIVT-MEQVTSLQNKLQDKEEHL----RNLQEKYADVINQIEILRS 1325 L++ + TQE ++ + E+ +L +++Q+KE + +NL ++ + + +E + + Sbjct: 1009 LINLKYNDTQERLKQLQSECEEYNNLISQIQEKERKISLANQNLVQENKRIQSVVEQITN 1068 Query: 1326 EIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXX 1385 E+ ++K +++ EN K+ EQ + NA+L++ Sbjct: 1069 ELREQKQE-NSNLKECNDAICEKQANIQRENDRIKEQLEQYV----NANAKLEEKVENLI 1123 Query: 1386 XXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYE 1445 + + +++ ++L L ++ +K +E +I L + N+E + Q E+ Sbjct: 1124 LENDSHSTENLALKQERIQIEYRLSLSQNQ-SEKLNERSILLARENEEMKLNAIQREEFI 1182 Query: 1446 KRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESV-----S 1500 I+ +++ + + ++ + M K+ + E L +++N E Sbjct: 1183 AAIQQQLIDQQHDSVLRNNLQNQEVDKLNKMIKQLKDELTSLKQQMNSSNQEREQQLINQ 1242 Query: 1501 LNKQVAELNKALEE--EVAKTNEMQTALENQ---EIEIVTLNDEITNLQN-MVRASSSKI 1554 LN AEL E+ + K N+ ++ + ++E+++ ++ T L+N +++ S+K+ Sbjct: 1243 LNSSQAELQDFQEKLLIIRKENKQLNDIKGELQAQLEVISKRNQETQLENELLQKESTKL 1302 Query: 1555 QK 1556 ++ Sbjct: 1303 KE 1304 Score = 111 bits (268), Expect = 1e-22 Identities = 174/955 (18%), Positives = 412/955 (43%), Gaps = 68/955 (7%) Query: 677 ELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELL 736 ++ + ++D+E + +++ LE + E+ + ++Q+ + K + +K+ E L Sbjct: 178 DILYALNLFEIDRENMEKSLRHLEQETENFATQTL-FMQQGS--STKGNDLGYQKLFEEL 234 Query: 737 AKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLE 796 + N++ + K+ ++ A+ E E EL + + ++E+ +A E + + Sbjct: 235 REENNQLKMKLVSEPLKSAR--ESVEISRKYEDELDSIQIKYDKIEKQLAKTEKKCQDRK 292 Query: 797 RKADQLGSYLQEKQKAYSEYTIQEDEL-VNRLAVLMDHDR------VVEKQLLEIEHENK 849 +L L++K+K + + L VN + D+ ++EKQ+ EI+ +N+ Sbjct: 293 ATIKKLYFLLEDKEKEVESLMQELENLRVNFQNKFQESDQRGQSIYILEKQIAEIQRQNQ 352 Query: 850 ELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTK--YQTQLRDLESNL 907 E+ E + L S+ + QQ Y + T L +S + + +L+ L Sbjct: 353 EMVNSRNERKENLEELNRSILEAQQKYKIQCREDFPTTLMRWKSVRDFFTDRLKILSMQK 412 Query: 908 KRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEK--NIEYV-TQLEAQL 964 + E + L + ++E+E + ++ + + K + E+ + I++V Q+E +L Sbjct: 413 EEAVDEQEKLRDELQREVE-RNLTLEERLTNYLNQLKQMEERERRLNEIQFVKEQVEKRL 471 Query: 965 QE----YKNNIENLNMNVEELNKMNLELIDKHVQ-KQQTQSPDYTEQYINE--------- 1010 +E Y+N I L + + L + N ++ + ++ K+Q + +N+ Sbjct: 472 EETEIHYENVIHKLEIEIRRLQEENQQIRKEFLETKEQIDFERINQNTLNDRKLQESQDT 531 Query: 1011 -INKLNALLKQKDEEIIALNQKINNAQVSYMSMV---SDYESKLAQFTTKLENMEEEMQR 1066 +L + +E+ +Q I+ Q + + E K + K E +E+E ++ Sbjct: 532 WERRLQQCATEWQKEVEQRDQLISQKQRELEAQIRISQQNERKKIEIQQKYEALEKEKEK 591 Query: 1067 VSKQLLDS--KQHNEELQILVREQDDQIKELKETKLTF-----EMNIPKTEGMIISSTIE 1119 ++ DS ++ ++QIL E + LK +++ E+ K EG + ++T + Sbjct: 592 REEE-FDSILQEQKRKIQILNEEVTQKKVALKSAQISIQDAHEELAHRKNEGHVWNATEQ 650 Query: 1120 PMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKII--Q 1177 + + LK +++ ++ S+L+ + ++ E+ + +I Q Sbjct: 651 QIKEKIALQKSRLQDCEEENAQLK-RDKLALNEKISILESKLSESQKEISKIQEDLIKQQ 709 Query: 1178 LETLNTELTGHDVVN--QEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQ-RGFE 1234 L +L N ++QI L+++L ++ S A S ++ + + + + Sbjct: 710 QVKLEVQLNQESQANNYRKQIETLRAQLHEVQNAIKIKESAYAVANSELNESRELIQEMK 769 Query: 1235 IAELWKQHLAQREADFQKT-EHELRVQLSAFESKYEQLLDS--VQSSTQEETNKIVTMEQ 1291 + L H Q+ AD + +R E + QL +S ++S +E+ K V Sbjct: 770 LEALRASHKQQQIADENNNLQSSVREWQRRAEQQQSQLEESRQIRSIIEEQQKKKVDELL 829 Query: 1292 VTSLQNKLQDK--EEHLRNLQEKYADVINQIEILRSEIEDEKVA---FXXXXXXXXXXXX 1346 + Q + Q EE L+ ++ + + I+IL ++++++ A F Sbjct: 830 MVIKQRETQQSCIEEELKAIKLSWENAERAIQILEEKLQEKERAQELFADQAQRELDSQH 889 Query: 1347 XXXXDL-RTENQSYKQMQEQSILNIN--EENAQLKKSSXXXXXXXXXXXXRVNDAEAKVL 1403 +L R +N+ + + ++ N +E + + + +AKV+ Sbjct: 890 DRIEELMRIQNKLENDLSQANLFNDKSIKEIELFQNQIQSLTQMNHELQQLIEEQQAKVI 949 Query: 1404 ELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIED---LTYEKESELA 1460 + T Q ++ ++ + K E L+ + +E N+++Q+++ E ++E + + + E Sbjct: 950 QNTDQKTIQ-AQQHAKRMELQQQLSNKEEECLNIQKQVIDLETQLEKQIRMFEDLQRENN 1008 Query: 1461 ILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAK-T 1519 ++ LK ++ + +Q E E E LI ++ K + N+ + + NK ++ V + T Sbjct: 1009 LINLKYNDTQERLKQLQSECE-EYNNLISQIQEKERKISLANQNLVQENKRIQSVVEQIT 1067 Query: 1520 NEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDN 1574 NE++ + + + ND I Q ++ + +I++ + + +E+++N Sbjct: 1068 NELREQ-KQENSNLKECNDAICEKQANIQRENDRIKEQLEQYVNANAKLEEKVEN 1121 Score = 108 bits (259), Expect = 1e-21 Identities = 267/1474 (18%), Positives = 620/1474 (42%), Gaps = 131/1474 (8%) Query: 213 DTKQQMTKMQENFIA-----MEAEWKDEKQ--RLLKDIESKDVRISSLEEANKLLEAARF 265 +++++++K+QE+ I +E + E Q K IE+ ++ ++ A K+ E+A Sbjct: 693 ESQKEISKIQEDLIKQQQVKLEVQLNQESQANNYRKQIETLRAQLHEVQNAIKIKESAYA 752 Query: 266 EISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQS--IEPSCEEKTEIEEKGSLEIANMTE 323 + E ++ + +++ +A ++ ++ S E E+ ++ + Sbjct: 753 VANSELNESRELIQEMKLEALRASHKQQQIADENNNLQSSVREWQRRAEQQQSQLEESRQ 812 Query: 324 LTKKIELLEHLNC-QIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKM 382 + IE + ++ K+ E + + + E KA+ + I + + Sbjct: 813 IRSIIEEQQKKKVDELLMVIKQRETQQSCIEEELKAIKLSWENAERAIQILEEK---LQE 869 Query: 383 KSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXX 442 K +L ++ ++ D + ++ I +L + L DL + + ++K Sbjct: 870 KERAQELFADQAQRELDSQHDR--IEELMRIQNKLENDL-SQANLFNDKSIKEIELFQNQ 926 Query: 443 XGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLI 502 T + + + + + + T + AK E +Q N E + +N++ + Sbjct: 927 IQSLTQMNHELQQLIEEQQAKVIQNTDQKTIQAQQHAKRMELQQQLSNKEEECLNIQKQV 986 Query: 503 EKLKSAEEQITQLNDEIDAANKNMIKVKSNH-KLKLKQMQKTIDNFS-----------KV 550 L++ E+ ++ +++ N N+I +K N + +LKQ+Q + ++ K+ Sbjct: 987 IDLETQLEKQIRMFEDLQREN-NLINLKYNDTQERLKQLQSECEEYNNLISQIQEKERKI 1045 Query: 551 SDSNKEIV----RLTEELHHLSQKVAELEEEKGNLQL---HLVDYDSGRMIESDVYKKMI 603 S +N+ +V R+ + ++ ++ E ++E NL+ + + + E+D K+ + Sbjct: 1046 SLANQNLVQENKRIQSVVEQITNELREQKQENSNLKECNDAICEKQANIQRENDRIKEQL 1105 Query: 604 EMENLAETRL--KAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCS-EIK 660 E A +L K +L+ + L + Q++ ++E +L+ +SQ QS+++ I Sbjct: 1106 EQYVNANAKLEEKVENLILENDSHSTENLALKQERI-QIEYRLS-LSQNQSEKLNERSIL 1163 Query: 661 SVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENM-D 719 E++ + ++E I+ +D++ +L+N + D +NK+ +++ + Sbjct: 1164 LARENEEMKLNAIQREEFIAAIQQQLIDQQHDSVLRNNLQNQEVDKLNKMIKQLKDELTS 1223 Query: 720 LTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELS------K 773 L ++ + E+ +L+ ++N Q+++Q I++ + + +I+ EL Sbjct: 1224 LKQQMNSSNQEREQQLINQLN-SSQAELQDFQEKLLIIRKENKQLNDIKGELQAQLEVIS 1282 Query: 774 YKSRICRLEESIAVMEDRRYSLERK--ADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLM 831 +++ +LE + E + E++ ++Q+ Q+ QK DEL Sbjct: 1283 KRNQETQLENELLQKESTKLKEEKRNQSEQIRDLNQKCQKLEEREKNMIDELQVLKESFK 1342 Query: 832 DHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDL--- 888 + R E LLE+E K + E +Q L + + L N+ + Sbjct: 1343 NIHRDKESALLELETSLASGTAKEALKGAELDQVQSELKKVTRRLE-LESTENKKKIQQL 1401 Query: 889 -AESESTKYQT-----QLRDLE----SNLKRIT--HEHQTLIVQKKKEIEDLEIEFNTQI 936 E+E K QT +LR LE + ++RI + T + ++K E++ + ++ Sbjct: 1402 QTENEELKKQTDQEREKLRKLEYEAPNQIERINQLYARVTELNEQKSELQFKQDVLSSAH 1461 Query: 937 ESAIRDKKVLN---EKYEKNIEYV-----TQLEAQLQEYKNNIENLNMNVEELNKMNLEL 988 E ++K++L ++ +KN++ + Q+E + ++Y N ++NLN+ +E+ + L+L Sbjct: 1462 EQLKQEKELLQYQLDQAQKNVQMIQNSHKEQIEERDKKYLNLMKNLNLKDQEIQE--LKL 1519 Query: 989 IDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQK--INNAQVSYMSMVSDY 1046 ++ ++K TE I E +LN + +++I AL ++ + + + V Y Sbjct: 1520 LNSQIEKDAQTLKINTELKIQENQELNQKVLNLNDQIQALQEQAAVTQQNIQQQNEVR-Y 1578 Query: 1047 ESK---LAQFTTKLE--NMEEEMQRVSKQLLDSKQHNEELQILVRE--QDDQIKELKETK 1099 SK L + + ++ N EE +Q + K N + Q+ + K K +K Sbjct: 1579 PSKSPSLKKISECIDSPNQEEYVQDPINKFASQKSENPKKQVSYSQISNPPSRKSSKHSK 1638 Query: 1100 LTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQE 1159 + + + + + D++ ++ K E ++ Q+++ + + Sbjct: 1639 NQINQD-NNNDHYDVDNNENQLQDESEQLEFQGNLDNSQKEKSKRMERDDESQQQANVPK 1697 Query: 1160 QSAKLNTELQECYTKIIQLETLNTELTGHDVVNQ-EQINQLKSKLEQLNTENDNL--LST 1216 +S Y+KI + + + +NQ ++ +Q +LE L + ++ +S Sbjct: 1698 KSVS--------YSKISNISSRKSSENYQQSLNQGQEDDQEFEELEYLGNQKNSQREMSM 1749 Query: 1217 VAELRSS---ISSAVDQRGFEIAELWKQHLAQREADFQK-TEHELRVQLSAFESKYEQLL 1272 AE I S D FEI +++ + D Q ++ ++ + +Q+ Sbjct: 1750 KAEKTEEYNIIPSQEDFNEFEIDFNSQKNKSIDNRDLQNIASNKSLPKIKSQNQSSKQI- 1808 Query: 1273 DSVQSSTQEETNKIV--TMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDE 1330 +S Q + N+I+ +++ LQ +++ + + N Q + ++ +QIE L+S I ++ Sbjct: 1809 -PFESQVQSQQNQIIEELQDKLNELQLEIETLSQQMLNYQSENQELNDQIEKLKS-INEK 1866 Query: 1331 KVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQ-------SILNINEENAQLKKSSXX 1383 L+ + + +K ++ +I N+ + + S Sbjct: 1867 MTTDNLDLTNQVNSHEIKEKKLQQQFEQFKNSSQENEKKLSKNIQNMERQIVDEQNKSNQ 1926 Query: 1384 XXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIY---QKTHEYTITLTQRNDEFENVRQQ 1440 ++N A+ ++LE ++ + EI + + + T+ D+ E+ + Sbjct: 1927 LKQQIQQLQQQINLAKDEILEQNERISAQQQEIVLGENQIDQQSQTILLLQDKIESQAEY 1986 Query: 1441 LVEYEKRI-EDLTY--EKESELAILRLKMHENAN-HYETMQK-ESEIE-RVKLIEELNVK 1494 L E+ + E Y + E+ L R ++ E+ N ET Q+ + E++ + + I +L Sbjct: 1987 LKHVEEELKEQKNYASQLENNLEKKRKQLEESDNLQIETEQRLKQELQLKYEYIAKLEST 2046 Query: 1495 ITESVSLN-KQVAELNKALEEEVAK-TNEMQTALENQEIEIVTLNDEITNLQNMVRASSS 1552 L Q + L+ EV + ++ A ++Q I L +I +LQ +R + Sbjct: 2047 YKNKAELTLAQSQQATAELQSEVNRLKQQLAEAKQDQNIN-EGLKRQIRDLQRQLREVNM 2105 Query: 1553 KIQK----HVSFASDTKQGRDEQLDNTMNKELLD 1582 + +K + D R Q D + E+L+ Sbjct: 2106 EYEKLLIERQQYEDDMNLQRLSQQDLAIKFEVLE 2139 Score = 99.1 bits (236), Expect = 9e-19 Identities = 191/1106 (17%), Positives = 479/1106 (43%), Gaps = 78/1106 (7%) Query: 212 EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271 ++ +++++ +N + + +++ ++ + S+L+E N + + I E+ Sbjct: 1039 QEKERKISLANQNLVQENKRIQSVVEQITNELREQKQENSNLKECNDAICEKQANIQREN 1098 Query: 272 SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCE------EKTEIEEKGSLEIANMTELT 325 ++ ++LEQ L ++ S E E+ +IE + SL +L Sbjct: 1099 DRIKEQLEQYVNANAKLEEKVENLILENDSHSTENLALKQERIQIEYRLSLSQNQSEKLN 1158 Query: 326 KKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSP 385 ++ LL N +++ + E +A + + + + ++ ++ K+ Sbjct: 1159 ERSILLARENEEMKLNAIQREEFIAAI--QQQLI---DQQHDSVLRNNLQNQEVDKLNKM 1213 Query: 386 WSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGK 445 QL E + +++N + + + +I LN + + + K Sbjct: 1214 IKQLKDELTS--LKQQMNSSNQEREQQLINQLNSSQAELQDFQEKLLIIRKENKQLNDIK 1271 Query: 446 DTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNE-IAKVQEQLKQELNDEIKDVNVKDLIEK 504 L AQL++ +++ E T+ NE + K +LK+E ++ + ++DL +K Sbjct: 1272 GELQAQLEVISKRNQE----------TQLENELLQKESTKLKEEKRNQSE--QIRDLNQK 1319 Query: 505 LKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTI-DNFSKVSDSNKEIVRLTEE 563 + EE+ + DE+ ++ + + + L +++ ++ +K + E+ ++ E Sbjct: 1320 CQKLEEREKNMIDELQVLKESFKNIHRDKESALLELETSLASGTAKEALKGAELDQVQSE 1379 Query: 564 LHHLSQKV-AELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQ 622 L +++++ E E K +Q + + + +K+ ++E A +++ I+ L ++ Sbjct: 1380 LKKVTRRLELESTENKKKIQQLQTENEELKKQTDQEREKLRKLEYEAPNQIERINQLYAR 1439 Query: 623 KFDLVQELHILQQKYD---EVEDKL---ADISQLQSDQVCSEIKSVHLEEQIDALSASKK 676 +L ++ LQ K D ++L ++ Q Q DQ ++ + + KK Sbjct: 1440 VTELNEQKSELQFKQDVLSSAHEQLKQEKELLQYQLDQAQKNVQMIQNSHKEQIEERDKK 1499 Query: 677 ELALVIENLKL-DKE--QLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKL----EKMSA 729 L L ++NL L D+E +L +E D + + + IQEN +L K+ +++ A Sbjct: 1500 YLNL-MKNLNLKDQEIQELKLLNSQIEKDAQTLKINTELKIQENQELNQKVLNLNDQIQA 1558 Query: 730 EKISELLAKINHEEQSKIQ--TQFGIDAKIQE------RDLYIENIESELSKYKSRICRL 781 + + + N ++Q++++ ++ KI E ++ Y+++ ++ + KS + Sbjct: 1559 LQEQAAVTQQNIQQQNEVRYPSKSPSLKKISECIDSPNQEEYVQDPINKFASQKSENPKK 1618 Query: 782 EESIAVMED--RRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVL-----MDHD 834 + S + + + R S + +Q+ Q+ + + E++L + L +D+ Sbjct: 1619 QVSYSQISNPPSRKSSKHSKNQIN---QDNNNDHYDVDNNENQLQDESEQLEFQGNLDNS 1675 Query: 835 RVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESEST 894 + + + +E + E+++ + + ++ IS ++Y + + D E E Sbjct: 1676 QKEKSKRMERDDESQQQANVPKKSVSYSKISNISSRKSSENYQQSLNQGQEDD-QEFEEL 1734 Query: 895 KYQTQLRDLESNLK-RITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKN 953 +Y ++ + + + + I+ +++ + EI+FN+Q +I ++ + N K+ Sbjct: 1735 EYLGNQKNSQREMSMKAEKTEEYNIIPSQEDFNEFEIDFNSQKNKSIDNRDLQNIASNKS 1794 Query: 954 IEYV-TQLEAQLQ-EYKNNIEN-LNMNVEEL-NKMN-LELIDKHVQKQQTQSPDYTEQYI 1008 + + +Q ++ Q +++ +++ N +EEL +K+N L+L + + +Q ++ Sbjct: 1795 LPKIKSQNQSSKQIPFESQVQSQQNQIIEELQDKLNELQLEIETLSQQMLNYQSENQELN 1854 Query: 1009 NEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVS 1068 ++I KL ++ ++ + + L ++N+ ++ + +E + + + +Q + Sbjct: 1855 DQIEKLKSINEKMTTDNLDLTNQVNSHEIKEKKLQQQFEQFKNSSQENEKKLSKNIQNME 1914 Query: 1069 KQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNV 1128 +Q++D + + +L+ +++ QI K+ L I + I+ + + + Sbjct: 1915 RQIVDEQNKSNQLKQQIQQLQQQINLAKDEILEQNERISAQQQEIVLGE-NQIDQQSQTI 1973 Query: 1129 DXXXXXXXXXXXXLKVQEEEEFIQER--SVLQEQSAKLNTELQECYTKIIQLETLNTELT 1186 LK EEE Q+ S L+ K +L+E + +Q+ET L Sbjct: 1974 LLLQDKIESQAEYLKHVEEELKEQKNYASQLENNLEKKRKQLEE--SDNLQIET-EQRLK 2030 Query: 1187 GHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQR 1246 + E I +L+S + + + L+ + + + S V++ ++AE KQ Sbjct: 2031 QELQLKYEYIAKLESTYK---NKAELTLAQSQQATAELQSEVNRLKQQLAEA-KQDQNIN 2086 Query: 1247 EADFQKTEHELRVQLSAFESKYEQLL 1272 E ++ +L+ QL +YE+LL Sbjct: 2087 EG-LKRQIRDLQRQLREVNMEYEKLL 2111 Score = 98.3 bits (234), Expect = 2e-18 Identities = 215/1131 (19%), Positives = 472/1131 (41%), Gaps = 113/1131 (9%) Query: 499 KDLIEKLKSAEEQITQLNDE---IDAANKNMIKVKSNHKLKLKQ-MQKTIDNFSKVSDSN 554 K + E + +E + N+ ++ N+++++ + +K++ ++ T+ + V D Sbjct: 342 KQIAEIQRQNQEMVNSRNERKENLEELNRSILEAQQKYKIQCREDFPTTLMRWKSVRDF- 400 Query: 555 KEIVRLTEELHHLSQKVAELEEEKGNLQLHLV-DYDSGRMIESDV--YKKMIEMENLAET 611 T+ L LS + E +E+ L+ L + + +E + Y ++ E Sbjct: 401 -----FTDRLKILSMQKEEAVDEQEKLRDELQREVERNLTLEERLTNYLNQLKQMEERER 455 Query: 612 RLKAISLLESQKFDLVQELHILQQKYDEVEDKLA-DISQLQSDQVCSEIKSVHLEEQIDA 670 RL I ++ Q ++E I Y+ V KL +I +LQ + + + +EQID Sbjct: 456 RLNEIQFVKEQVEKRLEETEI---HYENVIHKLEIEIRRLQEENQQIRKEFLETKEQID- 511 Query: 671 LSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAE 730 + +N D++ L+ ++ +LQ E ++ +++ ++ Sbjct: 512 -------FERINQNTLNDRK--------LQESQDTWERRLQQCATEWQKEVEQRDQLISQ 556 Query: 731 KISELLAKIN---HEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAV 787 K EL A+I E+ KI+ Q +A +E++ E +S L + K +I L E + Sbjct: 557 KQRELEAQIRISQQNERKKIEIQQKYEALEKEKEKREEEFDSILQEQKRKIQILNEEVTQ 616 Query: 788 MEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHE 847 + S + L ++ + E ++ ++A + + +L + E E Sbjct: 617 KKVALKSAQISIQDAHEELAHRKNEGHVWNATEQQIKEKIA-------LQKSRLQDCEEE 669 Query: 848 NKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNL 907 N +L++ L E+ L+ LS+ Q+ + + E DL + + K + QL ES Sbjct: 670 NAQLKRDKLALNEKISILESKLSESQKEISKIQE-----DLIKQQQVKLEVQLNQ-ESQA 723 Query: 908 KRITHEHQTLIVQKKKEIEDLEIEFNTQ--IESAIRDKKVLNEKYEKNIEYVTQLEAQLQ 965 + +TL Q + ++I+ + S + + + L ++ + + + Q+ Sbjct: 724 NNYRKQIETLRAQLHEVQNAIKIKESAYAVANSELNESRELIQEMKLEALRASHKQQQIA 783 Query: 966 EYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEI 1025 + NN+++ +V E + + + + +Q +S EQ ++++L ++KQ++ + Sbjct: 784 DENNNLQS---SVREWQRRAEQQQSQLEESRQIRS-IIEEQQKKKVDELLMVIKQRETQQ 839 Query: 1026 IALNQKINNAQVSYMS---MVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQ 1082 + +++ ++S+ + + E KL + E ++ QR LDS QH + ++ Sbjct: 840 SCIEEELKAIKLSWENAERAIQILEEKLQEKERAQELFADQAQRE----LDS-QH-DRIE 893 Query: 1083 ILVREQDDQIKELKETKLTFEMNIPKTE---GMIISST----------IEPMSDDANNVD 1129 L+R Q+ +L + L + +I + E I S T E + N D Sbjct: 894 ELMRIQNKLENDLSQANLFNDKSIKEIELFQNQIQSLTQMNHELQQLIEEQQAKVIQNTD 953 Query: 1130 XXXXXXXXXXXXLKVQEEEEFIQERSV-LQEQSAKLNTELQECYTKIIQLETLNTELTGH 1188 +++Q++ +E + +Q+Q L T+L++ L+ N + Sbjct: 954 QKTIQAQQHAKRMELQQQLSNKEEECLNIQKQVIDLETQLEKQIRMFEDLQRENNLINLK 1013 Query: 1189 DVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREA 1248 QE++ QL+S+ E+ N NL+S + E IS A + Q + ++ Sbjct: 1014 YNDTQERLKQLQSECEEYN----NLISQIQEKERKISLA--------NQNLVQENKRIQS 1061 Query: 1249 DFQKTEHELRVQLSAFESKYEQLLDSV---QSSTQEETNKI-VTMEQVTSLQNKLQDKEE 1304 ++ +ELR Q S ++ D++ Q++ Q E ++I +EQ + KL++K E Sbjct: 1062 VVEQITNELREQKQE-NSNLKECNDAICEKQANIQRENDRIKEQLEQYVNANAKLEEKVE 1120 Query: 1305 HLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQ- 1363 +L + E + + + + I+ E E +Q Sbjct: 1121 NL--ILENDSHSTENLALKQERIQIEYRLSLSQNQSEKLNERSILLARENEEMKLNAIQR 1178 Query: 1364 EQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVL-ELTHQLELKDSEIYQKTHE 1422 E+ I I ++ + S ++N ++ ELT + +S ++ + Sbjct: 1179 EEFIAAIQQQLIDQQHDSVLRNNLQNQEVDKLNKMIKQLKDELTSLKQQMNSSNQEREQQ 1238 Query: 1423 YTITLTQRNDEFENVRQQLV---EYEKRIEDLTYEKESELAILRLKMHENANHYETMQKE 1479 L E ++ +++L+ + K++ D+ E +++L ++ + E E +QKE Sbjct: 1239 LINQLNSSQAELQDFQEKLLIIRKENKQLNDIKGELQAQLEVISKRNQETQLENELLQKE 1298 Query: 1480 S------EIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTN-EMQTALENQEIE 1532 S + + + I +LN K + K + + + L+E + + ++AL E Sbjct: 1299 STKLKEEKRNQSEQIRDLNQKCQKLEEREKNMIDELQVLKESFKNIHRDKESALLELETS 1358 Query: 1533 IV--TLNDEITNLQ-NMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKEL 1580 + T + + + + V++ K+ + + S + + +QL T N+EL Sbjct: 1359 LASGTAKEALKGAELDQVQSELKKVTRRLELESTENKKKIQQL-QTENEEL 1408 >UniRef50_Q22CJ7 Cluster: Putative uncharacterized protein; n=1; Tetrahymena thermophila SB210|Rep: Putative uncharacterized protein - Tetrahymena thermophila SB210 Length = 1640 Score = 124 bits (300), Expect = 2e-26 Identities = 211/1037 (20%), Positives = 444/1037 (42%), Gaps = 92/1037 (8%) Query: 555 KEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLK 614 +E+ +EL + + K++EL EEKG L + D E V K +IE L E + Sbjct: 582 RELEEQVKELVNENSKLSELLEEKGYLLQQIQD-------EQLVQKLLIENNELKEKLRQ 634 Query: 615 AISLLESQKFDLVQELHILQQKYDEV-EDKLADISQLQSDQVCSEIKSVHLEEQIDALSA 673 A +E+ + LH +++ +K+ +I +L+ +++ +S + ++D L Sbjct: 635 A--QMENDLSIQNRVLHTENTNLNKILSEKVKEIRELK-EKLQQNSQSQESQRKVDQLER 691 Query: 674 SKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNK---LQNYIQENMDLTDKLEKMSAE 730 + K L E+L +Q ++ +D ++ NK LQ+YIQE + + + +S E Sbjct: 692 NIKLLIQENEHLSDVLKQRQSEVQKQRDDNLEMQNKVINLQSYIQELQEQQSRQQSISNE 751 Query: 731 KISEL----------LAKINHEEQSKIQTQFGIDAKIQERDLYI----ENIESELSKY-K 775 K + L LA+ HE Q K Q I+ + +++ + E + +S+Y Sbjct: 752 KFNSLKSEYDKIQNKLAEKEHELQQKEQNAQKINREAEDQITKLVDENEKLNEIISQYIN 811 Query: 776 SRICRLEESIAVMEDR-RYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHD 834 S L S+A+ ++ + ++ + ++ Q +Y E+++ N +A + + Sbjct: 812 SSNTDLLNSMAINKNTSKLNIVKDDEEKLQMFDSLQNCNKDY---EEKIKNLIAQNKNLE 868 Query: 835 RVV---EKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAES 891 V+ EK +E+ + ++ + +++ ++N +LQ+ + + + A E A++ L ES Sbjct: 869 EVILDLEKDKIELAENLQFMEDRQKVIEKQNDDLQMEIEKLSKQETACTEIADKVKLLES 928 Query: 892 ESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYE 951 ++ Q+ + L + + E+Q ++ Q + E +IE R + L E + Sbjct: 929 QNQDLHLQIDQMNQGLTQKSEENQLIVQQNENNKNYFEQIIQEKIEQINRLSQQLQE--Q 986 Query: 952 KNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLE--LIDKHVQKQQTQSPDYTEQYIN 1009 N Q + Q+Q+ E+ + N + L + Q+ S D ++ I Sbjct: 987 SNFIQALQQQQQIQQIHEREEDEQEEEKTKKAANKKQTLPSQRYQRDDQISEDEDQEQIQ 1046 Query: 1010 EINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYES---KLAQFTTKLENMEEEMQR 1066 + N+ N +K D LN+ + S + + +S +L +F +L+ + ++ Sbjct: 1047 QQNQENN-IKSADSTFNQLNEDNYFDKESEQLIETPLDSNTFELTKFQKELKEKNDIIKN 1105 Query: 1067 VSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDAN 1126 + + L K+ EL V++Q I +L+E K+ N +G I + S+D Sbjct: 1106 LCENLDFQKEQVSELNEKVQQQAIFIIDLQE-KIKKSQNEINQQGEKILELLSNASED-- 1162 Query: 1127 NVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQS-AKLNTELQECYTKIIQLETLNTEL 1185 Q ++E +Q++ ++ + + ++E KII L+ L EL Sbjct: 1163 --QSISKSQRKSREIASQQNDQELLQQQLEYKDHAIQEYILVIRELDDKIINLQKLLKEL 1220 Query: 1186 TGH-DVVNQEQINQLKS-KLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHL 1243 + N I +L+S L N N+ + ++ I V Q+ + KQ Sbjct: 1221 KPDLQLDNSFYIERLESLNLLSPNISNNLKERKITQMEERILIQVQQQDNDEDNHQKQ-- 1278 Query: 1244 AQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKE 1303 Q + QK + + ++S F+ KY+Q ++ ++ N+ E++ SL N + Sbjct: 1279 -QNLINPQKIQSLIDREISQFDQKYKQKMEELEKEMSVSINE--RDEKIVSLIN----EN 1331 Query: 1304 EHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQ 1363 + L L E+ + +++IL +IE K D +T K++Q Sbjct: 1332 QKLLQLNEQR---LIELKILNQQIEMRK--------------EQNIRDTKTIEDLQKKIQ 1374 Query: 1364 EQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEY 1423 NI + LK S + N +E +++ + E ++S+ Sbjct: 1375 MMLSKNIQQNKGILKNSQ----------HFQQNTSERSLIDSIREEESEESQDVDSQKNQ 1424 Query: 1424 TITLTQRNDEFENVRQQLVEYEKRIEDLTYEKES-ELAILRLKMHENANHYETMQKESEI 1482 +Q + E + ++++L E +++ D E E+ + +L + E E Q + E+ Sbjct: 1425 QQHASQ-SHEAKRLQRKLEEKRRQLSDAKQELENLKEKLLDFEEIEFRLTSENRQLQEEV 1483 Query: 1483 ERVKLIEELNVKITESVSLNK-QVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEIT 1541 R+ + N ++ E + K + EL K E A+ +E+ L++ + + + ++++ Sbjct: 1484 RRLSQHSDENNRLNEMLKTRKNEYTELKKRFEALRAERDELIQKLKDSQFQDGSPSNQLN 1543 Query: 1542 NLQNMVRASSSKIQKHV 1558 N ++ +S ++ K + Sbjct: 1544 NSKSF-NVNSFELYKEI 1559 Score = 107 bits (258), Expect = 2e-21 Identities = 213/1084 (19%), Positives = 483/1084 (44%), Gaps = 114/1084 (10%) Query: 297 KQSIEPSCEEKTEIEEKGSL-EIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTE 355 K+ + + + +EEKG L + +L +K+ L+E+ + + ++EN L+ + Sbjct: 589 KELVNENSKLSELLEEKGYLLQQIQDEQLVQKL-LIENNELKEKLRQAQMENDLSI---Q 644 Query: 356 SKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQ 415 ++ + + + + ++S K +++ +L + +Q++ +K+++ E ++++IQ Sbjct: 645 NRVLHTENTNLNKILSEK-----VKEIRELKEKLQQNSQSQESQRKVDQLE-RNIKLLIQ 698 Query: 416 SLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDV 475 N+ L D V+ ++ + + LQ Q+ E S +N E Sbjct: 699 E-NEHLSD---VLKQRQSEVQKQRDDNLEMQNKVINLQSYIQELQEQQSRQQSISN-EKF 753 Query: 476 NEIAKVQEQLKQELNDEIKDVNVKDL-IEKL-KSAEEQITQLNDEIDAANKNMIKVKSNH 533 N + ++++ +L ++ ++ K+ +K+ + AE+QIT+L DE + N+ + + ++ Sbjct: 754 NSLKSEYDKIQNKLAEKEHELQQKEQNAQKINREAEDQITKLVDENEKLNEIISQYINSS 813 Query: 534 KLKLKQMQKTIDNFSKVS--DSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSG 591 L N SK++ ++E +++ + L + ++ + EE+ NL + + Sbjct: 814 NTDLLNSMAINKNTSKLNIVKDDEEKLQMFDSLQNCNK---DYEEKIKNL---IAQNKNL 867 Query: 592 RMIESDVYKKMIEM-ENL--AETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADIS 648 + D+ K IE+ ENL E R K I E Q DL E+ L K + ++AD Sbjct: 868 EEVILDLEKDKIELAENLQFMEDRQKVI---EKQNDDLQMEIEKL-SKQETACTEIADKV 923 Query: 649 QLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMN 708 +L Q ++ + +++ L+ +E L+++ + +K I++ + Sbjct: 924 KLLESQ--NQDLHLQIDQMNQGLTQKSEENQLIVQQNENNKNYFEQIIQEKIEQINRLSQ 981 Query: 709 KLQ---NYI---QENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQE--- 759 +LQ N+I Q+ + E+ E+ E K +++Q+ ++ D +I E Sbjct: 982 QLQEQSNFIQALQQQQQIQQIHEREEDEQEEEKTKKAANKKQTLPSQRYQRDDQISEDED 1041 Query: 760 -RDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTI 818 + +N E+ + S +L E ++ +E D L + QK E Sbjct: 1042 QEQIQQQNQENNIKSADSTFNQLNEDNYFDKESEQLIETPLDSNTFELTKFQKELKE--- 1098 Query: 819 QEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNA 878 +++++ L +D + +Q+ E+ N+++Q++ +++ + ++ S +++ Q Sbjct: 1099 -KNDIIKNLCENLDFQK---EQVSEL---NEKVQQQAIFIIDLQEKIKKSQNEINQQGEK 1151 Query: 879 LVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIES 938 ++E + +S S K Q + R++ S ++ ++Q++ E +D I+ + Sbjct: 1152 ILELLSNASEDQSIS-KSQRKSREIAS------QQNDQELLQQQLEYKDHAIQEYILVIR 1204 Query: 939 AIRDKKVLNEKYEKNIE---------YVTQLEAQLQEYKNNIENLNMNVEELNKMNLELI 989 + DK + +K K ++ Y+ +LE+ L NI N N+ ++ +M ++ Sbjct: 1205 ELDDKIINLQKLLKELKPDLQLDNSFYIERLES-LNLLSPNISN-NLKERKITQMEERIL 1262 Query: 990 ----------DKHVQKQQTQSPDYTEQYIN-EINKLNALLKQKDEEI-IALNQKINNAQV 1037 D H ++Q +P + I+ EI++ + KQK EE+ ++ IN Sbjct: 1263 IQVQQQDNDEDNHQKQQNLINPQKIQSLIDREISQFDQKYKQKMEELEKEMSVSINERDE 1322 Query: 1038 SYMSMVSDYESKLAQFT------TKLENMEEEMQRVSKQLLDSK---QHNEELQILVREQ 1088 +S++++ KL Q K+ N + EM R + + D+K +++Q+++ + Sbjct: 1323 KIVSLINE-NQKLLQLNEQRLIELKILNQQIEM-RKEQNIRDTKTIEDLQKKIQMMLSKN 1380 Query: 1089 DDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEE 1148 Q K + + F+ N +E +I S E S+++ +VD + + + Sbjct: 1381 IQQNKGILKNSQHFQQN--TSERSLIDSIREEESEESQDVDSQKNQQQHASQSHEAKRLQ 1438 Query: 1149 EFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNT 1208 ++E+ + Q + EL+ K++ E + LT + QE++ +L ++ Sbjct: 1439 RKLEEK---RRQLSDAKQELENLKEKLLDFEEIEFRLTSENRQLQEEVRRLSQ-----HS 1490 Query: 1209 ENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLS---AFE 1265 + +N L+ + + R + + + +R FE + L Q+ D Q + QL+ +F Sbjct: 1491 DENNRLNEMLKTRKNEYTELKKR-FEALRAERDELIQKLKDSQFQDGSPSNQLNNSKSFN 1549 Query: 1266 SKYEQLLDSVQSSTQE--ETNKI--VTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIE 1321 +L ++S +E E KI + Q+ + ++ +K E L ++ K ++ QI+ Sbjct: 1550 VNSFELYKEIESIKKENHELKKINEQCIVQIKKKEKEIDEKMEELDQVKNKCNELTEQIK 1609 Query: 1322 ILRS 1325 S Sbjct: 1610 TSNS 1613 Score = 95.1 bits (226), Expect = 1e-17 Identities = 180/878 (20%), Positives = 388/878 (44%), Gaps = 102/878 (11%) Query: 389 LSSETLNQDTDK-KINKNEIAKLEMV--IQSLNKDLVDK-EYVISEKDTXXXXXXXXXXG 444 L+S +N++T K I K++ KL+M +Q+ NKD +K + +I++ Sbjct: 818 LNSMAINKNTSKLNIVKDDEEKLQMFDSLQNCNKDYEEKIKNLIAQNKNLEEVILDLEKD 877 Query: 445 KDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEK 504 K L LQ ME + N + EI K+ +Q + ++ +K Sbjct: 878 KIELAENLQF-----MEDRQKVIEKQNDDLQMEIEKLSKQ----------ETACTEIADK 922 Query: 505 LKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSK-VSDSNKEIVRLTEE 563 +K E Q L+ +ID N+ + + ++L ++Q + + F + + + ++I RL+++ Sbjct: 923 VKLLESQNQDLHLQIDQMNQGLTQKSEENQLIVQQNENNKNYFEQIIQEKIEQINRLSQQ 982 Query: 564 LHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQK 623 L S + L++++ Q+H + + E K + + L R + + S+ Sbjct: 983 LQEQSNFIQALQQQQQIQQIH--EREEDEQEEEKTKKAANKKQTLPSQRYQRDDQI-SED 1039 Query: 624 FDLVQELHILQQKYDEVEDKLAD--ISQLQSDQVCSEIKSVHLEEQIDALSASKKELALV 681 D Q +QQ+ E K AD +QL D + +E +D ++ EL Sbjct: 1040 EDQEQ----IQQQNQENNIKSADSTFNQLNEDNYFDKESEQLIETPLD---SNTFELTKF 1092 Query: 682 IENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQEN----MDLTDKLEK------MSAEK 731 + LK + + ++L+ KE + ++L +Q+ +DL +K++K EK Sbjct: 1093 QKELKEKNDIIKNLCENLDFQKEQV-SELNEKVQQQAIFIIDLQEKIKKSQNEINQQGEK 1151 Query: 732 ISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAV---M 788 I ELL+ + ++ + + Q+ D E ++ +L +YK ++E I V + Sbjct: 1152 ILELLSNASEDQSISKSQRKSREIASQQNDQ--ELLQQQL-EYKDH--AIQEYILVIREL 1206 Query: 789 EDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHEN 848 +D+ +L++ +L LQ Y I+ E +N L+ + ++ + E+++ ++E E Sbjct: 1207 DDKIINLQKLLKELKPDLQLDNSFY----IERLESLNLLSPNISNN-LKERKITQME-ER 1260 Query: 849 KELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTD-----LAESESTKYQTQLRDL 903 +Q + Q E+N Q +L + Q+ + + + ++ D E + + + Sbjct: 1261 ILIQVQQQDNDEDNHQKQQNLINPQKIQSLIDREISQFDQKYKQKMEELEKEMSVSINER 1320 Query: 904 ESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQI----ESAIRDKKVLNEKYEKNIEYVTQ 959 + + + +E+Q L+ ++ + +L+I N QI E IRD K + E +K I+ + Sbjct: 1321 DEKIVSLINENQKLLQLNEQRLIELKI-LNQQIEMRKEQNIRDTKTI-EDLQKKIQMM-- 1376 Query: 960 LEAQLQEYK---NNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYI---NEINK 1013 L +Q+ K N ++ N E + ++ ++ + Q S +Q+ +E + Sbjct: 1377 LSKNIQQNKGILKNSQHFQQNTSERSLIDSIREEESEESQDVDSQKNQQQHASQSHEAKR 1436 Query: 1014 LNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLD 1073 L L++K ++ Q++ N + + D+E + T++ ++EE++R+S+ Sbjct: 1437 LQRKLEEKRRQLSDAKQELENLKEKLL----DFEEIEFRLTSENRQLQEEVRRLSQH--- 1489 Query: 1074 SKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXX 1133 N L +++ + ++ ELK+ FE + +I + D + + Sbjct: 1490 -SDENNRLNEMLKTRKNEYTELKK---RFEA-LRAERDELIQKLKDSQFQDGSPSNQLNN 1544 Query: 1134 XXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQ 1193 ++ +E E I++ + + K+N ++C I+Q++ E+ Sbjct: 1545 SKSFNVNSFELYKEIESIKKEN---HELKKIN---EQC---IVQIKKKEKEID----EKM 1591 Query: 1194 EQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQR 1231 E+++Q+K+K +L TE ++ + +I DQ+ Sbjct: 1592 EELDQVKNKCNEL-TEQIKTSNSAPQSICTIQGQEDQK 1628 Score = 81.0 bits (191), Expect = 2e-13 Identities = 159/782 (20%), Positives = 332/782 (42%), Gaps = 72/782 (9%) Query: 839 KQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQT 898 K+L E+E + KEL +N L E + L +Q LV+K L E+ K + Sbjct: 579 KKLRELEEQVKELVNENSKLSELLEEKGYLLQQIQD--EQLVQKL----LIENNELKEKL 632 Query: 899 QLRDLESNL---KRITHEHQT----LIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYE 951 + +E++L R+ H T ++ +K KEI +L+ + +S +KV ++ E Sbjct: 633 RQAQMENDLSIQNRVLHTENTNLNKILSEKVKEIRELKEKLQQNSQSQESQRKV--DQLE 690 Query: 952 KNIEYVTQ----LEAQLQEYKNNIE-NLNMNVEELNK-MNLELIDKHVQKQQTQSPDYTE 1005 +NI+ + Q L L++ ++ ++ + N+E NK +NL+ + +Q+QQ++ + Sbjct: 691 RNIKLLIQENEHLSDVLKQRQSEVQKQRDDNLEMQNKVINLQSYIQELQEQQSRQQSISN 750 Query: 1006 QYIN----EINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKL-ENM 1060 + N E +K+ L +K+ E L QK NAQ D +KL KL E + Sbjct: 751 EKFNSLKSEYDKIQNKLAEKEHE---LQQKEQNAQ-KINREAEDQITKLVDENEKLNEII 806 Query: 1061 EEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEP 1120 + + + LL+S N+ L +DD+ K L N K I + I Sbjct: 807 SQYINSSNTDLLNSMAINKNTSKLNIVKDDEEKLQMFDSL---QNCNKDYEEKIKNLI-- 861 Query: 1121 MSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLET 1180 A N + +++ E +F+++R Q+ K N +LQ K+ + ET Sbjct: 862 ----AQNKNLEEVILDLEKDKIELAENLQFMEDR---QKVIEKQNDDLQMEIEKLSKQET 914 Query: 1181 LNTELTGHDVVNQEQINQLKSKLEQLN------TENDNLLSTVAELRSSISSAVDQRGFE 1234 TE+ + + Q L +++Q+N +E + L+ E + + Q E Sbjct: 915 ACTEIADKVKLLESQNQDLHLQIDQMNQGLTQKSEENQLIVQQNENNKNYFEQIIQEKIE 974 Query: 1235 IAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEE----TNKIVTME 1290 Q L ++ Q + + ++Q + EQ + + + ++ + + + Sbjct: 975 QINRLSQQLQEQSNFIQALQQQQQIQQIHEREEDEQEEEKTKKAANKKQTLPSQRYQRDD 1034 Query: 1291 QVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXX 1350 Q++ +++ Q ++++ N + NQ+ ++ + Sbjct: 1035 QISEDEDQEQIQQQNQENNIKSADSTFNQLNEDNYFDKESEQLIETPLDSNTFELTKFQK 1094 Query: 1351 DLRTENQSYKQM------QEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLE 1404 +L+ +N K + Q++ + +NE+ Q +N K+LE Sbjct: 1095 ELKEKNDIIKNLCENLDFQKEQVSELNEKVQQQAIFIIDLQEKIKKSQNEINQQGEKILE 1154 Query: 1405 LTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIED-LTYEKESELAILR 1463 L +D I + + +Q+ND+ E ++QQL + I++ + +E + I+ Sbjct: 1155 LLSNAS-EDQSISKSQRKSREIASQQNDQ-ELLQQQLEYKDHAIQEYILVIRELDDKIIN 1212 Query: 1464 L-KMHENANHYETMQKESEIERVKLIEELNVKITESVSLNK--QVAE--LNKALEEEVAK 1518 L K+ + + IER++ + L+ I+ ++ K Q+ E L + +++ + Sbjct: 1213 LQKLLKELKPDLQLDNSFYIERLESLNLLSPNISNNLKERKITQMEERILIQVQQQDNDE 1272 Query: 1519 TN--EMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTM 1576 N + Q + Q+I+ + ++ EI+ + +++K +S + + RDE++ + + Sbjct: 1273 DNHQKQQNLINPQKIQSL-IDREISQFDQKYKQKMEELEKEMSVSINE---RDEKIVSLI 1328 Query: 1577 NK 1578 N+ Sbjct: 1329 NE 1330 Score = 39.1 bits (87), Expect = 0.99 Identities = 44/199 (22%), Positives = 95/199 (47%), Gaps = 21/199 (10%) Query: 1395 VNDAEAKVLELTHQL-EL--KDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDL 1451 +N K+ EL Q+ EL ++S++ + E L Q DE + V++ L+E + E L Sbjct: 574 LNSNSKKLRELEEQVKELVNENSKLSELLEEKGYLLQQIQDE-QLVQKLLIENNELKEKL 632 Query: 1452 TY-EKESELAILRLKMH-ENANHYETMQKESEIERVKLIEELNVKI---TESVSLNKQVA 1506 + E++L+I +H EN N + + E+VK I EL K+ ++S ++V Sbjct: 633 RQAQMENDLSIQNRVLHTENTNLNKILS-----EKVKEIRELKEKLQQNSQSQESQRKVD 687 Query: 1507 ELNKALEEEVAKTNEMQTALENQEIEI-------VTLNDEITNLQNMVRASSSKIQKHVS 1559 +L + ++ + + + L+ ++ E+ + + +++ NLQ+ ++ + + S Sbjct: 688 QLERNIKLLIQENEHLSDVLKQRQSEVQKQRDDNLEMQNKVINLQSYIQELQEQQSRQQS 747 Query: 1560 FASDTKQGRDEQLDNTMNK 1578 +++ + D NK Sbjct: 748 ISNEKFNSLKSEYDKIQNK 766 >UniRef50_UPI00006CD102 Cluster: Kinesin motor domain containing protein; n=1; Tetrahymena thermophila SB210|Rep: Kinesin motor domain containing protein - Tetrahymena thermophila SB210 Length = 1593 Score = 124 bits (299), Expect = 2e-26 Identities = 218/1116 (19%), Positives = 478/1116 (42%), Gaps = 108/1116 (9%) Query: 494 KDVNV-KDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNF-SKVS 551 +DV++ K L +K EE I+ L EID I+ + +KL++ ++ +F SK+ Sbjct: 470 QDVDIIKALTQKSDMEEEGISSLLTEIDQTIVEDIQQMTQTCIKLEEFEERRKDFTSKLE 529 Query: 552 DSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAET 611 E+ L + + ++ EK ++L ++ + + + ++ E Sbjct: 530 KIGLMNFGCPEKEKELEEAI--IQREKRIIELQNEQAHQNKLFNQQLEEISNQRDHFKEV 587 Query: 612 RLKAISLLESQKFDLVQELHILQQKYDE----VEDKLADISQLQSDQVCSEIKSVHLEEQ 667 S ++S + + + + ++K + E KLA+ Q S+ +IK++ L ++ Sbjct: 588 NQGLNSEIQSLQQQIAKNVQTHEEKIQQFKNGFESKLAEYDQNSSE---IKIKNMELADE 644 Query: 668 IDALSASKKELALVIENLKLDKEQLY-------GTIKDLENDKEDIMNKLQNYIQENMDL 720 ID L + + L + +++K E Y T ++EN K+ I ++L +EN +L Sbjct: 645 IDELKSHIENLNRIKDDIKQKWENAYENYQKTLQTKNEIENQKDSIQSQLNISREENTNL 704 Query: 721 TDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICR 780 KL + + L + E++ Q I K + + + IE E + ++ I + Sbjct: 705 MFKLSEAENLYNQDRLHMMTLEDELNSQKNI-IQEKDHQINNLVSRIEEENLRLQATIDK 763 Query: 781 LEESIAVMEDR----RYSLE---RKADQLGSYLQEK-------QKAYSEYTIQEDELVNR 826 ++ IA +ED+ + +E + + L L+EK Q+ Y + Q ++ N Sbjct: 764 QKDDIASLEDQITKSKEDIEIACQTLEFLNKQLEEKCQVNIQLQETYKQEFNQREKFENE 823 Query: 827 LAVLMDHDR-----------VVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQH 875 L L +++ + EKQ+ EIE E + K L + LQ L + ++ Sbjct: 824 LKYLYHNEKSQLNVALKQNEIFEKQIQEIEQEITQKMDKITDLEHDILGLQEKLKNNEKR 883 Query: 876 YNAL-VEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNT 934 N+L VEK + E+E Q Q++D +K I +T + Q +++E E+ Sbjct: 884 LNSLEVEKEYYRN--ETEQQIQQIQIKD--DKIKEINQALETAL-QMGEQLEMGVQEYEK 938 Query: 935 QIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQ 994 Q K+L+E+ + + + + QL++ + I M E L + EL + + Sbjct: 939 Q-------NKILSEQLLQKEQEILEKILQLEDAEQKIRVSQMTHELLTQKISEL-ESQLG 990 Query: 995 KQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFT 1054 +Q T + + +Q + + L+ QK+ ++I N + + + E + Sbjct: 991 EQITLNTGFQDQIVLLSEEKKDLI-QKEAQLIESNLEQEKTIIELKENLQQLEQLCKEKE 1049 Query: 1055 TKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMII 1114 T++E ++ + + K D +Q + V+EQ++++ E + FE+ + + + Sbjct: 1050 TQIEQIKSDFYELKKSSEDYQQIQDHELKSVKEQNNKLNE-QVQNYEFEVQNMQQKASQM 1108 Query: 1115 SSTIEPMS---DDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQEC 1171 +E + + + K Q+ EE IQER V +E+ K+ T+ Sbjct: 1109 EEDMEVLKQEIQEKQELYLQSEKSKEEQISQKNQKIEELIQERQVYEEEFDKIQTKYSNQ 1168 Query: 1172 YTKIIQL-ETLNTELTGHDVVNQE-QINQLKSKLEQLNTENDNLLSTVAELRSSIS-SAV 1228 I +L ++ T ++ + ++ + N++ L+Q+ +N+NL+ + + + Sbjct: 1169 MRNISELQQSFQAARTENESIKKQIEDNRVFIYLQQIQ-QNENLMIHFCNKKGQMEIFQL 1227 Query: 1229 DQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVT 1288 +++ FEI KQ L Q+ ++ + + F+ + EQ+ + + ++ + Sbjct: 1228 EKQKFEIE---KQKLETERQTIQQEMYQKDILIQKFKEEQEQI--GCKFEIFKTLHEQIE 1282 Query: 1289 MEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXX 1348 EQ Q+K +K + L N ++KY + +E L +EK+ Sbjct: 1283 -EQKNVYQSKYVNKSKELDNYEQKYNTLEQAMERL-----NEKLTIKQLENNKLTNQILI 1336 Query: 1349 XXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQ 1408 R +NQ ++ ++ + EE +Q+K+ + K L L Q Sbjct: 1337 MQSNREKNQFTQEDLQRDLKKSREECSQIKQ-------------------KYKALILERQ 1377 Query: 1409 LELKDSEIYQ-KTHEYTITLTQRNDEFENVRQQLVEY----EKRIEDLTYEKESELAILR 1463 ++ + + + ++ I + + +E ++ Q +Y EK+I ++ + ++ Sbjct: 1378 VQSQQANRFNGNANDQNIIIKKLEEENNKIKDQFNKYKQISEKKINEICEKLNRGISTAT 1437 Query: 1464 LKMHENANHYETMQKESEIERVKLIEELNVKITE-SVSLNKQVAELNKALEEEVAKTNEM 1522 + + + +N E +K ++ ++I E N+ I E ++ + + + K + K +E Sbjct: 1438 I-VKDISNSTEIAKKLE--KQCEIINEKNMGILEINILVRNYLIDCKKGQIDPTQK-DEY 1493 Query: 1523 QTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHV 1558 +++QE + L + ++++ V K+Q+ + Sbjct: 1494 LEKIQSQE-DTTALKEVLSSVLKSVEERERKVQQEM 1528 Score = 115 bits (276), Expect = 1e-23 Identities = 207/1075 (19%), Positives = 454/1075 (42%), Gaps = 92/1075 (8%) Query: 481 VQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQM 540 ++ Q +Q +++ + ++++ + +E LN EI + + + K H+ K++Q Sbjct: 557 IELQNEQAHQNKLFNQQLEEISNQRDHFKEVNQGLNSEIQSLQQQIAKNVQTHEEKIQQF 616 Query: 541 QKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYK 600 + ++ D N +++ L+ ++ EL+ NL D + Y+ Sbjct: 617 KNGFESKLAEYDQNSSEIKIKN--MELADEIDELKSHIENLNRIKDDIKQKWENAYENYQ 674 Query: 601 KMI----EMENLAETRLKAISLLESQKFDLVQELHILQQKYDE-------VEDKL---AD 646 K + E+EN ++ +++ + +L+ +L + Y++ +ED+L + Sbjct: 675 KTLQTKNEIENQKDSIQSQLNISREENTNLMFKLSEAENLYNQDRLHMMTLEDELNSQKN 734 Query: 647 ISQLQSDQVCSEIKSVHLEE-QIDA-LSASKKELALVIENLKLDKEQLYGTIKDLENDKE 704 I Q + Q+ + + + E ++ A + K ++A + + + KE + + LE + Sbjct: 735 IIQEKDHQINNLVSRIEEENLRLQATIDKQKDDIASLEDQITKSKEDIEIACQTLEFLNK 794 Query: 705 DIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYI 764 + K Q IQ + T K E EK L + H E+S++ + +++ I Sbjct: 795 QLEEKCQVNIQ--LQETYKQEFNQREKFENELKYLYHNEKSQLNVALKQNEIFEKQ---I 849 Query: 765 ENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQL----GSYLQEKQKAYSEYTIQE 820 + IE E+++ +I LE I ++++ + E++ + L Y E ++ + I++ Sbjct: 850 QEIEQEITQKMDKITDLEHDILGLQEKLKNNEKRLNSLEVEKEYYRNETEQQIQQIQIKD 909 Query: 821 DEL--VNR-LAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQ--ISLSDMQQH 875 D++ +N+ L + +E + E E +NK L + Q+L +E + L+ + L D +Q Sbjct: 910 DKIKEINQALETALQMGEQLEMGVQEYEKQNKILSE--QLLQKEQEILEKILQLEDAEQK 967 Query: 876 YNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQ 935 V + +L + ++ ++QL + + L + L+ ++KK++ E + Sbjct: 968 IR--VSQMTH-ELLTQKISELESQLGE-QITLNTGFQDQIVLLSEEKKDLIQKEAQL--- 1020 Query: 936 IESAIRDKKVLNEKYEKNIEYVTQL----EAQLQEYKNNIENLNMNVEELNKMNLELIDK 991 IES + +K + E ++N++ + QL E Q+++ K++ L + E+ ++ + K Sbjct: 1021 IESNLEQEKTIIE-LKENLQQLEQLCKEKETQIEQIKSDFYELKKSSEDYQQIQDHEL-K 1078 Query: 992 HVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLA 1051 V++Q + + + Y E+ + Q +E++ L Q+I Q Y+ E +++ Sbjct: 1079 SVKEQNNKLNEQVQNYEFEVQNMQQKASQMEEDMEVLKQEIQEKQELYLQSEKSKEEQIS 1138 Query: 1052 QFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEG 1111 Q K+E + +E Q + EE + + +Q++ + E + +F+ +TE Sbjct: 1139 QKNQKIEELIQERQ----------VYEEEFDKIQTKYSNQMRNISELQQSFQ--AARTEN 1186 Query: 1112 MIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTE---- 1167 I IE K + E F E+ + + KL TE Sbjct: 1187 ESIKKQIEDNRVFIYLQQIQQNENLMIHFCNKKGQMEIFQLEKQKFEIEKQKLETERQTI 1246 Query: 1168 LQECYTKIIQLETLNTE-----------LTGHDVVNQEQINQLKSKLEQLNTENDNL--- 1213 QE Y K I ++ E T H+ + +EQ N +SK + E DN Sbjct: 1247 QQEMYQKDILIQKFKEEQEQIGCKFEIFKTLHEQI-EEQKNVYQSKYVNKSKELDNYEQK 1305 Query: 1214 LSTVAELRSSISSAVDQRGFEIAELWKQHL---AQREADFQKTEHELRVQLSAFESKYEQ 1270 +T+ + ++ + + E +L Q L + RE + Q T+ +L+ L + Q Sbjct: 1306 YNTLEQAMERLNEKLTIKQLENNKLTNQILIMQSNREKN-QFTQEDLQRDLKKSREECSQ 1364 Query: 1271 LLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDE 1330 + ++ E + V +Q D+ ++ L+E+ + +Q + +I ++ Sbjct: 1365 IKQKYKALILE---RQVQSQQANRFNGNANDQNIIIKKLEEENNKIKDQFNKYK-QISEK 1420 Query: 1331 KVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXX 1390 K+ D+ + K++++Q + INE+N + + + Sbjct: 1421 KINEICEKLNRGISTATIVKDISNSTEIAKKLEKQCEI-INEKNMGILEINILVRNYLID 1479 Query: 1391 XXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIED 1450 D K L +D+ ++ + + + V+Q++ + +++ Sbjct: 1480 CKKGQIDPTQKDEYLEKIQSQEDTTALKEVLSSVLKSVEERE--RKVQQEMYQLKEKKAS 1537 Query: 1451 LTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQV 1505 Y + S+ L + +E N ET +K +R ++E V I + LNK+V Sbjct: 1538 YEYYR-SKCEELEFR-YEKKNS-ETGEKILNRKRKLSVKENEVPILGEIDLNKKV 1589 Score = 102 bits (244), Expect = 9e-20 Identities = 169/839 (20%), Positives = 370/839 (44%), Gaps = 69/839 (8%) Query: 479 AKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLK 538 +K+ E + +IK++ + D I++LKS E + ++ D+I +N + N++ K Sbjct: 622 SKLAEYDQNSSEIKIKNMELADEIDELKSHIENLNRIKDDIKQKWENAYE---NYQ-KTL 677 Query: 539 QMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDV 598 Q + I+N S I R EE +L K++E E +LH++ + E + Sbjct: 678 QTKNEIENQKDSIQSQLNISR--EENTNLMFKLSEAENLYNQDRLHMMTLED----ELNS 731 Query: 599 YKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSE 658 K +I+ ++ L +S +E + LQ D+ +D DI+ L+ DQ+ Sbjct: 732 QKNIIQEKDHQINNL--VSRIEEENLR-------LQATIDKQKD---DIASLE-DQITKS 778 Query: 659 IKSVHLE-EQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQEN 717 + + + + ++ L+ +E V L+ +Q + + EN+ + + + ++ + Sbjct: 779 KEDIEIACQTLEFLNKQLEEKCQVNIQLQETYKQEFNQREKFENELKYLYHNEKSQLNVA 838 Query: 718 MDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSR 777 + + EK E E+ K++ + G+ K++ + + ++E E Y++ Sbjct: 839 LKQNEIFEKQIQEIEQEITQKMDKITDLE-HDILGLQEKLKNNEKRLNSLEVEKEYYRNE 897 Query: 778 ICRLEESIAVMEDRRYSLERKAD---QLGSYLQ------EKQ-KAYSEYTIQ-EDELVNR 826 + + I + +D+ + + + Q+G L+ EKQ K SE +Q E E++ + Sbjct: 898 TEQQIQQIQIKDDKIKEINQALETALQMGEQLEMGVQEYEKQNKILSEQLLQKEQEILEK 957 Query: 827 LAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRT 886 + L D +Q + + EL + LE QI+L+ Q L+ + + Sbjct: 958 ILQLED-----AEQKIRVSQMTHELLTQKISELESQLGEQITLNTGFQDQIVLLSE-EKK 1011 Query: 887 DLAESESTKYQTQLRDLES--NLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKK 944 DL + E+ ++ L ++ LK + + L +K+ +IE ++ +F +++ + D + Sbjct: 1012 DLIQKEAQLIESNLEQEKTIIELKENLQQLEQLCKEKETQIEQIKSDF-YELKKSSEDYQ 1070 Query: 945 VLNEKYEKNI-EYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQ---TQS 1000 + + K++ E +L Q+Q Y+ ++N+ ++ + ++E++ + +Q++Q QS Sbjct: 1071 QIQDHELKSVKEQNNKLNEQVQNYEFEVQNMQQKASQMEE-DMEVLKQEIQEKQELYLQS 1129 Query: 1001 PDYTEQYINEIN-KLNALLKQK---DEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTK 1056 E+ I++ N K+ L++++ +EE + K +N M +S+ + T+ Sbjct: 1130 EKSKEEQISQKNQKIEELIQERQVYEEEFDKIQTKYSN----QMRNISELQQSFQAARTE 1185 Query: 1057 LENMEEEMQRVSKQL-LDSKQHNEELQILVREQDDQIK--ELKETKLTFEMNIPKTEGMI 1113 E+++++++ + L Q NE L I + Q++ +L++ K E +TE Sbjct: 1186 NESIKKQIEDNRVFIYLQQIQQNENLMIHFCNKKGQMEIFQLEKQKFEIEKQKLETERQT 1245 Query: 1114 ISSTI---EPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQE 1170 I + + + L Q EE+ +S +S +L+ Q+ Sbjct: 1246 IQQEMYQKDILIQKFKEEQEQIGCKFEIFKTLHEQIEEQKNVYQSKYVNKSKELDNYEQK 1305 Query: 1171 CYTKIIQLETLNTELTGHDVVNQEQINQ---LKSKLEQLNTENDNLLSTVAELRSSISSA 1227 T +E LN +LT + N + NQ ++S E+ ++L + + R S Sbjct: 1306 YNTLEQAMERLNEKLTIKQLENNKLTNQILIMQSNREKNQFTQEDLQRDLKKSREECSQ- 1364 Query: 1228 VDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKI 1286 + Q+ ++ L +Q +Q+ F ++ + + E + ++ D Q KI Sbjct: 1365 IKQK-YKALILERQVQSQQANRFNGNANDQNIIIKKLEEENNKIKDQFNKYKQISEKKI 1422 Score = 96.7 bits (230), Expect = 5e-18 Identities = 196/1062 (18%), Positives = 428/1062 (40%), Gaps = 76/1062 (7%) Query: 507 SAEEQITQLNDEIDAANKNMIKVKSN--HKLKLKQMQKTIDNFSKVSDSNKEIVRLTEEL 564 S + LN + + MI VK++ H + L ++ + D KE + + L Sbjct: 219 SRSHSVFSLNFQSKIVSNGMIHVKNSKLHFVDLAGSERQ-KSTGAAGDRLKEASNINKSL 277 Query: 565 HHLSQKVAELEEEKGNLQLHLVDYDSG-RMIESDVY---KKMIEMENLAETRLKAISLLE 620 L + L E H+ DS I D + + +E + L Sbjct: 278 TVLGLVINALVESANGKSRHIPYRDSKLTFILKDSLGGNSRTFMIAACSEANTQFQETLS 337 Query: 621 SQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELAL 680 + KF Q +++ K E+ ++ QL+ + + + ++ + + ++K + Sbjct: 338 TLKF--AQRAKMIKNKASVNEESQGNVQQLKKEIQKLKEELQDAKKALQEMEENQKNMTR 395 Query: 681 VIENLKLDKEQLY--GTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAK 738 +I K + I+ + + ++I KL+ Q D D ++ +E L Sbjct: 396 IITPAKYTPTSMNHEAVIQFQQKNFKEINIKLEEVNQLLSDFNDSRSRIEEFFKNEKLGV 455 Query: 739 INHEEQSKIQTQFGIDAKI-----QERDLYIENIESELSKYKSRICRLEESIAVMEDRRY 793 + + Q + G D I Q+ D+ E I S L++ I E I M Sbjct: 456 LRVFQDIVDQKKMGQDVDIIKALTQKSDMEEEGISSLLTEIDQTIV---EDIQQMTQTCI 512 Query: 794 SLERKADQLGSYLQEKQK-AYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQ 852 LE ++ + + +K + E E A++ R++E Q E H+NK Sbjct: 513 KLEEFEERRKDFTSKLEKIGLMNFGCPEKEKELEEAIIQREKRIIELQN-EQAHQNKLFN 571 Query: 853 KKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESEST---KYQTQLRDLESNLKR 909 ++ LEE N + ++ Q N+ ++ + +A++ T K Q ES L Sbjct: 572 QQ----LEEISNQRDHFKEVNQGLNSEIQSLQQ-QIAKNVQTHEEKIQQFKNGFESKLAE 626 Query: 910 ITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYE---KNIEYVTQLEAQLQE 966 + + K E+ D E + IE+ R K + +K+E +N + Q + +++ Sbjct: 627 YDQNSSEIKI-KNMELADEIDELKSHIENLNRIKDDIKQKWENAYENYQKTLQTKNEIEN 685 Query: 967 YKNNIEN-LNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEI 1025 K++I++ LN++ EE + +L + Q + T + +E+N ++++KD +I Sbjct: 686 QKDSIQSQLNISREENTNLMFKLSEAENLYNQDRLHMMTLE--DELNSQKNIIQEKDHQI 743 Query: 1026 IALNQKINNAQVSYMSMVSDYESKLA----QFTTKLENME---EEMQRVSKQLLDSKQHN 1078 L +I + + + + +A Q T E++E + ++ ++KQL + Q N Sbjct: 744 NNLVSRIEEENLRLQATIDKQKDDIASLEDQITKSKEDIEIACQTLEFLNKQLEEKCQVN 803 Query: 1079 EELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXX 1138 +LQ +++ +Q +E E +L + + K++ + E ++ Sbjct: 804 IQLQETYKQEFNQ-REKFENELKYLYHNEKSQLNVALKQNEIFEKQIQEIE--------- 853 Query: 1139 XXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQ 1198 QE + + + + L+ L +L+ ++ LE + E ++ Q Q Q Sbjct: 854 ------QEITQKMDKITDLEHDILGLQEKLKNNEKRLNSLE-VEKEYYRNETEQQIQQIQ 906 Query: 1199 LKS-KLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHEL 1257 +K K++++N + L +L + Q +L ++ E Q + E Sbjct: 907 IKDDKIKEINQALETALQMGEQLEMGVQEYEKQNKILSEQLLQKEQEILEKILQLEDAEQ 966 Query: 1258 RVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVI 1317 ++++S +LL S + + + +T+ T Q+++ E ++L +K A +I Sbjct: 967 KIRVSQMT---HELLTQKISELESQLGEQITLN--TGFQDQIVLLSEEKKDLIQKEAQLI 1021 Query: 1318 -NQIEILRSEIE-----DEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNIN 1371 + +E ++ IE + +L+ ++ Y+Q+Q+ + ++ Sbjct: 1022 ESNLEQEKTIIELKENLQQLEQLCKEKETQIEQIKSDFYELKKSSEDYQQIQDHELKSVK 1081 Query: 1372 EENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRN 1431 E+N +L + + + E + L +++ K Q ++Q+N Sbjct: 1082 EQNNKLNEQVQNYEFEVQNMQQKASQMEEDMEVLKQEIQEKQELYLQSEKSKEEQISQKN 1141 Query: 1432 DEFENVRQQLVEYEKRIEDLTYEKESELA-ILRLKMHENANHYETMQKESEIERVKLIEE 1490 + E + Q+ YE+ + + + +++ I L+ A E + +IE ++ Sbjct: 1142 QKIEELIQERQVYEEEFDKIQTKYSNQMRNISELQQSFQAARTENESIKKQIEDNRVFIY 1201 Query: 1491 LNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIE 1532 L +I ++ +L + NK + E+ + + + +E Q++E Sbjct: 1202 LQ-QIQQNENL--MIHFCNKKGQMEIFQLEKQKFEIEKQKLE 1240 Score = 94.3 bits (224), Expect = 2e-17 Identities = 167/928 (17%), Positives = 404/928 (43%), Gaps = 71/928 (7%) Query: 409 KLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHV 468 K E ++ K L K + ++KD+ L+ +L +++ +H+ Sbjct: 665 KWENAYENYQKTLQTKNEIENQKDSIQSQLNISREENTNLM--FKLSEAENLYNQDRLHM 722 Query: 469 GTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEK--LKSAEEQITQLNDEIDAANKNM 526 T +++N + ++ ++N+ + + ++L + + ++ I L D+I + +++ Sbjct: 723 MTLEDELNSQKNIIQEKDHQINNLVSRIEEENLRLQATIDKQKDDIASLEDQITKSKEDI 782 Query: 527 IKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLV 586 + KQ+++ ++ ++ K+ E+ + + + E+ + N+ L Sbjct: 783 EIACQTLEFLNKQLEEKCQVNIQLQETYKQEFNQREKFENELKYLYHNEKSQLNVALKQN 842 Query: 587 DYDSGRM--IESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKY-DEVEDK 643 + ++ IE ++ +KM ++ +L L L++ + L L + ++ Y +E E + Sbjct: 843 EIFEKQIQEIEQEITQKMDKITDLEHDILGLQEKLKNNEKRL-NSLEVEKEYYRNETEQQ 901 Query: 644 LADISQLQSDQVCSEIK-----SVHLEEQID-ALSASKKELALVIENLKLDKEQLYGTIK 697 + I Q++ D++ EI ++ + EQ++ + +K+ ++ E L ++++ I Sbjct: 902 IQQI-QIKDDKI-KEINQALETALQMGEQLEMGVQEYEKQNKILSEQLLQKEQEILEKIL 959 Query: 698 DLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKI 757 LE+ ++ I ++ E LT K+ ++ ++ ++ ++Q + ++ D Sbjct: 960 QLEDAEQKI--RVSQMTHEL--LTQKISELESQLGEQITLNTGFQDQIVLLSEEKKDLIQ 1015 Query: 758 QERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYT 817 +E L N+E E + I L+E++ +E E + +Q+ S E +K+ +Y Sbjct: 1016 KEAQLIESNLEQEKT-----IIELKENLQQLEQLCKEKETQIEQIKSDFYELKKSSEDYQ 1070 Query: 818 -IQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHY 876 IQ+ EL + + + + + +Q+ E E + +Q+K + E+ + L+ + + Q+ Y Sbjct: 1071 QIQDHELKS----VKEQNNKLNEQVQNYEFEVQNMQQKASQMEEDMEVLKQEIQEKQELY 1126 Query: 877 NALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEF---- 932 L + ++ + ++ K + +++ + + + QT + + I +L+ F Sbjct: 1127 --LQSEKSKEEQISQKNQKIEELIQERQVYEEEFD-KIQTKYSNQMRNISELQQSFQAAR 1183 Query: 933 --NTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVE--ELNKMNLEL 988 N I+ I D +V Y + I+ L K +E + + E+ K LE Sbjct: 1184 TENESIKKQIEDNRVFI--YLQQIQQNENLMIHFCNKKGQMEIFQLEKQKFEIEKQKLET 1241 Query: 989 IDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYES 1048 + +Q++ Q +++ E ++ K E L+++I + Y S + Sbjct: 1242 ERQTIQQEMYQKDILIQKFKEEQEQIGC----KFEIFKTLHEQIEEQKNVYQSKYVNKSK 1297 Query: 1049 KLAQFTTKLENMEEEMQRVSKQLLDSKQHNEEL--QILVRE---------QDDQIKELKE 1097 +L + K +E+ M+R++++L + N +L QIL+ + Q+D ++LK+ Sbjct: 1298 ELDNYEQKYNTLEQAMERLNEKLTIKQLENNKLTNQILIMQSNREKNQFTQEDLQRDLKK 1357 Query: 1098 TKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQER-SV 1156 ++ K + +I+ ++ S AN + K++EE I+++ + Sbjct: 1358 SREECSQIKQKYKALILERQVQ--SQQANRFNGNANDQNIIIK--KLEEENNKIKDQFNK 1413 Query: 1157 LQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLST 1216 ++ S K E+ E + I T+ +++ + E +L+ + E +N +N +L Sbjct: 1414 YKQISEKKINEICEKLNRGISTATIVKDISN----STEIAKKLEKQCEIINEKNMGILEI 1469 Query: 1217 VAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQ 1276 +R+ + +D + +I K ++ Q+ L+ LS+ E+ VQ Sbjct: 1470 NILVRNYL---IDCKKGQIDPTQKDEYLEK-IQSQEDTTALKEVLSSVLKSVEERERKVQ 1525 Query: 1277 SSTQEETNKIVTMEQVTSLQNKLQDKEE 1304 + K + E S +L+ + E Sbjct: 1526 QEMYQLKEKKASYEYYRSKCEELEFRYE 1553 Score = 53.2 bits (122), Expect = 6e-05 Identities = 91/447 (20%), Positives = 186/447 (41%), Gaps = 44/447 (9%) Query: 1143 KVQEEEEFIQE-RSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVV---NQEQINQ 1198 ++Q+ +E +Q+ + LQE E Q+ T+II H+ V Q+ + Sbjct: 368 EIQKLKEELQDAKKALQEME-----ENQKNMTRIITPAKYTPTSMNHEAVIQFQQKNFKE 422 Query: 1199 LKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELR 1258 + KLE++N LLS + RS I + F+ +L + Q D +K ++ Sbjct: 423 INIKLEEVN----QLLSDFNDSRSRI-----EEFFKNEKLGVLRVFQDIVDQKKMGQDVD 473 Query: 1259 VQLSAFESKYEQLLDSVQSSTQEETNKIVT-MEQVTSLQNKLQDKEEHLRNLQEKYADVI 1317 + + A K + + + S E IV ++Q+T KL++ EE ++ K + Sbjct: 474 I-IKALTQKSDMEEEGISSLLTEIDQTIVEDIQQMTQTCIKLEEFEERRKDFTSK----L 528 Query: 1318 NQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQL 1377 +I ++ +++ + +N+ + Q E+ I N + ++ Sbjct: 529 EKIGLMNFGCPEKEKELEEAIIQREKRIIELQNEQAHQNKLFNQQLEE-ISNQRDHFKEV 587 Query: 1378 KKS-SXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFEN 1436 + + V E K+ + + E K +E Q + E I + DE + Sbjct: 588 NQGLNSEIQSLQQQIAKNVQTHEEKIQQFKNGFESKLAEYDQNSSEIKIKNMELADEIDE 647 Query: 1437 VRQQLVEYEKRIEDLTYEKESELAILRLKMHENA--NHYETMQKESEIERVK--LIEELN 1492 ++ +E RI+D +K ENA N+ +T+Q ++EIE K + +LN Sbjct: 648 LKSH-IENLNRIKDDIKQK-----------WENAYENYQKTLQTKNEIENQKDSIQSQLN 695 Query: 1493 VKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSS 1552 + E+ +L +++E ++ ++ L +Q+ I + +I NL + + + Sbjct: 696 ISREENTNLMFKLSEAENLYNQDRLHMMTLEDELNSQKNIIQEKDHQINNLVSRIEEENL 755 Query: 1553 KIQKHVSFASDTKQGRDEQLDNTMNKE 1579 ++Q + D ++Q+ T +KE Sbjct: 756 RLQATIDKQKDDIASLEDQI--TKSKE 780 Score = 53.2 bits (122), Expect = 6e-05 Identities = 145/727 (19%), Positives = 312/727 (42%), Gaps = 71/727 (9%) Query: 151 IKEKDNALSVLQVKMKIMETTILDLQEKI--NEKD-QIIEAKNKATTXXXXXXXXXXXXX 207 I+E + ++ K+ +E IL LQEK+ NEK +E + + Sbjct: 849 IQEIEQEITQKMDKITDLEHDILGLQEKLKNNEKRLNSLEVEKEYYRNETEQQIQQIQIK 908 Query: 208 XXXXEDTKQQMT---KMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAA- 263 ++ Q + +M E E++ + + L + + K+ I LE+ +L +A Sbjct: 909 DDKIKEINQALETALQMGEQLEMGVQEYEKQNKILSEQLLQKEQEI--LEKILQLEDAEQ 966 Query: 264 RFEIS-LEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMT 322 + +S + H L Q++ + Q + S E+K I+++ L +N+ Sbjct: 967 KIRVSQMTHELLTQKISELESQLGEQITLNTGFQDQIVLLSEEKKDLIQKEAQLIESNLE 1026 Query: 323 ELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKM 382 + IEL E+L Q+ Q KE E ++ + ++ + S+ + + + Sbjct: 1027 QEKTIIELKENLQ-QLEQLCKEKETQIEQIKSDFYELKKSSEDYQQIQDHE-----LKSV 1080 Query: 383 KSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKE--YVISEKDTXXXXXXX 440 K ++L+ + N + + + + + +++E ++ L +++ +K+ Y+ SEK Sbjct: 1081 KEQNNKLNEQVQNYEFEVQNMQQKASQMEEDMEVLKQEIQEKQELYLQSEKSKEEQISQ- 1139 Query: 441 XXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQE--QLKQELNDEIKDVNV 498 K+ I +L E Q + E I + + + I+++Q+ Q + N+ IK + Sbjct: 1140 ----KNQKIEELIQERQVYEEEFDKIQTKYSNQ-MRNISELQQSFQAARTENESIKK-QI 1193 Query: 499 KDLIEKLKSAEEQITQL-NDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEI 557 +D ++ +QI Q N I NK K ++ + QK K+ + I Sbjct: 1194 ED--NRVFIYLQQIQQNENLMIHFCNK-----KGQMEIFQLEKQKFEIEKQKLETERQTI 1246 Query: 558 VRLTEELHHLSQKVAELEEEKGNL-----QLHLVDYDSGRMIESDVYKKMIEMENLAETR 612 + + L QK E +E+ G LH + + +S K E++N + Sbjct: 1247 QQEMYQKDILIQKFKEEQEQIGCKFEIFKTLHEQIEEQKNVYQSKYVNKSKELDNYEQK- 1305 Query: 613 LKAISLLESQKFDLVQELHILQQKYDEVEDKLADI-SQLQSDQVCSEIKSVHLEEQIDAL 671 + LE L ++L I Q + +++ +++ + S + +Q E L++ + Sbjct: 1306 ---YNTLEQAMERLNEKLTIKQLENNKLTNQILIMQSNREKNQFTQEDLQRDLKKSREEC 1362 Query: 672 SASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEK 731 S K++ +I ++ +Q ND+ I+ KL+ + D +K +++S +K Sbjct: 1363 SQIKQKYKALILERQVQSQQA-NRFNGNANDQNIIIKKLEEENNKIKDQFNKYKQISEKK 1421 Query: 732 ISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRL--EESIAVME 789 I+E+ K+N GI +D I N +E++K + C + E+++ ++E Sbjct: 1422 INEICEKLNR----------GISTATIVKD--ISN-STEIAKKLEKQCEIINEKNMGILE 1468 Query: 790 ----DRRYSLERKADQL-----GSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQ 840 R Y ++ K Q+ YL EK ++ + T ++ L + L + + +R V+++ Sbjct: 1469 INILVRNYLIDCKKGQIDPTQKDEYL-EKIQSQEDTTALKEVLSSVLKSVEERERKVQQE 1527 Query: 841 LLEIEHE 847 + +++ + Sbjct: 1528 MYQLKEK 1534 Score = 51.6 bits (118), Expect = 2e-04 Identities = 149/712 (20%), Positives = 279/712 (39%), Gaps = 63/712 (8%) Query: 143 DVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXX 202 D+ L +K + L+ L+V+ + ++I KD I+ N+A Sbjct: 869 DILGLQEKLKNNEKRLNSLEVEKEYYRNETEQQIQQIQIKDDKIKEINQA----LETALQ 924 Query: 203 XXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEA 262 ++ ++Q + E + E E EK L+D E K +R+S + + Sbjct: 925 MGEQLEMGVQEYEKQNKILSEQLLQKEQEIL-EKILQLEDAEQK-IRVSQMTHELLTQKI 982 Query: 263 ARFEISL-EHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCE-EKTEIEEKGSLEIAN 320 + E L E L + Q IE + E EKT IE K +L+ Sbjct: 983 SELESQLGEQITLNTGFQDQIVLLSEEKKDLIQKEAQLIESNLEQEKTIIELKENLQ--Q 1040 Query: 321 MTELTKKIEL-LEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTA 379 + +L K+ E +E + + K E+ E K+V + K + + Sbjct: 1041 LEQLCKEKETQIEQIKSDFYELKKSSEDYQQIQDHELKSVKEQNNKLNEQVQNYEFEVQN 1100 Query: 380 SKMKSPWSQLSSETLNQDTDKKIN---KNEIAKLEMVIQSLNK--DLVDKEYVISEKDTX 434 + K+ + E L Q+ +K ++E +K E + Q K +L+ + V E+ Sbjct: 1101 MQQKASQMEEDMEVLKQEIQEKQELYLQSEKSKEEQISQKNQKIEELIQERQVYEEE--- 1157 Query: 435 XXXXXXXXXGKDTLIAQLQLEHQ-QHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEI 493 + I++LQ Q E S + ED N + +Q++Q N I Sbjct: 1158 FDKIQTKYSNQMRNISELQQSFQAARTENES---IKKQIED-NRVFIYLQQIQQNENLMI 1213 Query: 494 KDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDS 553 N K + +I QL + K ++ + ++ + QK I K + Sbjct: 1214 HFCN--------KKGQMEIFQLEKQKFEIEKQKLETE-RQTIQQEMYQKDI-LIQKFKEE 1263 Query: 554 NKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVY-KKMIEMENLAETR 612 ++I E L + ++EE+K Q V+ + E D Y +K +E E Sbjct: 1264 QEQIGCKFEIFKTLHE---QIEEQKNVYQSKYVN----KSKELDNYEQKYNTLEQAMERL 1316 Query: 613 LKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQ--LQSDQVCSEIKSVH----LEE 666 + +++ + + L ++ I+Q ++ + D+ + +S + CS+IK + LE Sbjct: 1317 NEKLTIKQLENNKLTNQILIMQSNREKNQFTQEDLQRDLKKSREECSQIKQKYKALILER 1376 Query: 667 QIDALSASKKELALVIENLKLDK-EQLYGTIKDLENDKEDIMNKLQNYIQE--NMDLTDK 723 Q+ + A++ +N+ + K E+ IKD N + I K N I E N ++ Sbjct: 1377 QVQSQQANRFNGNANDQNIIIKKLEEENNKIKDQFNKYKQISEKKINEICEKLNRGISTA 1436 Query: 724 LEKMSAEKISELLAKINHEEQSKIQTQFGI-DAKIQERDLYIENIESEL-----SKYKSR 777 +E+ K+ + + + GI + I R+ I+ + ++ +Y + Sbjct: 1437 TIVKDISNSTEIAKKLEKQCEIINEKNMGILEINILVRNYLIDCKKGQIDPTQKDEYLEK 1496 Query: 778 ICRLEESIAVMEDRRYSL------ERKADQLGSYLQEKQKAYSEYTIQEDEL 823 I E++ A+ E L ERK Q L+EK+ +Y Y + +EL Sbjct: 1497 IQSQEDTTALKEVLSSVLKSVEERERKVQQEMYQLKEKKASYEYYRSKCEEL 1548 >UniRef50_Q9XZE3 Cluster: Myosin heavy chain; n=1; Amoeba proteus|Rep: Myosin heavy chain - Amoeba proteus (Amoeba) Length = 2138 Score = 124 bits (299), Expect = 2e-26 Identities = 259/1254 (20%), Positives = 502/1254 (40%), Gaps = 80/1254 (6%) Query: 331 LEHLNCQIRQTNKELENKLATMGTE-SKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQL 389 L L Q ++ K+L+ A G + S+ ++ S S +S + T SK + L Sbjct: 942 LRDLKRQCDESEKKLKELEADAGKKKSEKAKQETEIASISASLESEKETNSKYQLQVRNL 1001 Query: 390 SSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLI 449 + D EIA L+ L+ +L D E E D L Sbjct: 1002 LRNLEEEKEDMARLDEEIANLQRFKDRLSLELDDLE---DELDEYTKVKQAAEKNISALN 1058 Query: 450 AQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAE 509 QL+ E ++ +E S + + K+ E LK L EI D + K+ + Sbjct: 1059 DQLK-ETKRELETESAARGASEANNKKYQEKIGE-LKGNLQREIGSNTTMD--KNNKALQ 1114 Query: 510 EQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQ 569 I++LND+ + N N K SN +LK K D S + D + + +RLT E L Sbjct: 1115 GNISELNDQTEDEN-NKKKTLSN-QLK-KVGDDLADVRSHIDDEHNQKLRLTNENTRLEA 1171 Query: 570 KV----AELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFD 625 + +L+E KG + + + DV + + EN K L K D Sbjct: 1172 AIDDLKRQLDETKGKISKLEKEKQQLQKHLEDVTAQFEDAENKFSQLTKTNLKL---KAD 1228 Query: 626 LVQELHILQQKYDEVEDKLAD-ISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIEN 684 L EL ++ D+ KL +++L+SD+ E + + + L A KK ++ Sbjct: 1229 L-DELQDNREGGDQAFQKLKKLVAKLESDKKMKEKEYEDERDLKNKLDAQKKLSQAELDG 1287 Query: 685 LKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQ 744 LK E++ E +++D+ N+L+ +L D+ E A + S L K E Sbjct: 1288 LKNALEEMAKNRSREEKNRKDLENRLR-------ELEDQAEDGQAAR-SNLEKKFRGFED 1339 Query: 745 SKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGS 804 + Q +D ++Q+ D+ + + + K +S + L+ S+ + R E K L + Sbjct: 1340 NLEDHQSQVD-EVQD-DVNV--LSAAKKKLESELEALKRSLDNEAEGRKVAEEKMKVLDT 1395 Query: 805 YLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQN 864 L E Q A S + LV + + D VE + E+ +KEL K L + N+ Sbjct: 1396 ELHELQLALSNAENKNTGLVRNVKKVQDE---VEDLNEQYENASKELSK----LDKGNKK 1448 Query: 865 LQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKK- 923 + L ++++H E + D E + Q +L +L L+ + + +L KK+ Sbjct: 1449 TEAELKELRRHVQ---ESQSSLDAGELKLRHTQDELDELHHQLEDLEAKSSSLERSKKQL 1505 Query: 924 EIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNK 983 +++ ++E + E A R K E+ K++E L A+LQE + E L + L Sbjct: 1506 QLQVDDLEDTHEEELAARTKA---ERLVKDLE--ADL-AELQETRVESEPLMQAEKALKS 1559 Query: 984 MNLELID--KHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMS 1041 + +EL+D K +Q + + + + L Q DE L + A+ + Sbjct: 1560 LEVELVDLKKDADRQSQAFAKVENERRSALREYEDLQAQLDETSKNL-ANADRAKKKLNT 1618 Query: 1042 MVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLT 1101 + + SKL + + +++E+ +++ K L +K + V +++ + + + L Sbjct: 1619 DLDEQLSKLEKASNAQKSLEKRLKKAEKDLAAAKAASARAGGGVSDEELRRAQAELAALR 1678 Query: 1102 FEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQE---EEEFIQERSVLQ 1158 + + ++ + ++ + + ++ L E+E + R L+ Sbjct: 1679 DDADRERSNKLTAEKRVKNLQAEIEDLKEMLEDEKTSKEALNRNNKSLEQELEELREQLE 1738 Query: 1159 EQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVA 1218 + LN + + K +++ L +L +++ QLK++LE+ + + L Sbjct: 1739 AEEEALNYLEEIKHKKDLEINELRKQLDAESEA-RDKFEQLKNELERDVADAKHNLEAEK 1797 Query: 1219 ELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSS 1278 + R+ + + EL K + K E E + L E++ +++++ Sbjct: 1798 KSRTDAEREAKKAEAQYDEL-KHRSEASDRGKDKLEKERKRALKELRLLREKV-EAIEAE 1855 Query: 1279 TQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXX 1338 E+ ++ + D E R EK A + LR ++ED K Sbjct: 1856 KDEQERLAWKFQEEVDALTEALDLEHKARVAHEKIA------KQLRVQLEDFKET-AEDA 1908 Query: 1339 XXXXXXXXXXXXDLRTENQSYK-QMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVND 1397 +L+ E + K Q+ E+ N E A K ++ R Sbjct: 1909 TRGKSRADQLTSELQAEIEDLKDQLDEEE--ERNRELANFKINNKSAIADLKKALDREIS 1966 Query: 1398 AEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKES 1457 A + E QLE ++E+ + E ++ R + R+ E E L S Sbjct: 1967 AREALEEAKRQLERDNNELRDQLDEERVS---RGNSERAARKSFAELEDTNARLNALNAS 2023 Query: 1458 ELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVA 1517 + + K A++ + ++ +++++ + E+ + L +V L L +E Sbjct: 2024 IGKLEKAKRRAEADYRASKKQLADLQKKEATED-----SLRAQLEAEVRRLKSRLVDEQD 2078 Query: 1518 KTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQ 1571 + + ++ E+EI L DE+ L + + + ++ ++ AS+ KQ +E+ Sbjct: 2079 RAADAESDRRRAEVEINKLRDEVRVLSDELERAKAEARQ----ASEDKQELEER 2128 Score = 113 bits (272), Expect = 4e-23 Identities = 241/1245 (19%), Positives = 499/1245 (40%), Gaps = 120/1245 (9%) Query: 145 THLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXX 204 T L N++ +K++ L +L+ + ++ + DL+ + +E E K K Sbjct: 915 TTLRNSMSKKESELDLLRGDISTGDSKLRDLKRQCDES----EKKLKELEADAGKKKSEK 970 Query: 205 XXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAAR 264 + +E ++++ + + LL+++E + ++ L+E L+ + Sbjct: 971 AKQETEIASISASLESEKET----NSKYQLQVRNLLRNLEEEKEDMARLDEEIANLQRFK 1026 Query: 265 FEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTEL 324 +SLE L EL++ L Q E E +TE +G+ E N Sbjct: 1027 DRLSLELDDLEDELDEYTKVKQAAEKNISALNDQLKETKRELETESAARGASEANNKKYQ 1086 Query: 325 TKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKS 384 K EL +L +I +N A G S+ + + +K+ N K+ Sbjct: 1087 EKIGELKGNLQREIGSNTTMDKNNKALQGNISELNDQTEDENN---KKKTLSNQLKKVGD 1143 Query: 385 PWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXG 444 + + S ++ K NE +LE I L + L + + G Sbjct: 1144 DLADVRSHIDDEHNQKLRLTNENTRLEAAIDDLKRQLDETK------------------G 1185 Query: 445 KDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEK 504 K + + + + + Q+H+E + + +++ K +LK +L DE++D Sbjct: 1186 KISKLEKEKQQLQKHLEDVTAQFEDAENK-FSQLTKTNLKLKADL-DELQD--------- 1234 Query: 505 LKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEEL 564 + +Q Q ++ A ++ K+K + ++ +D K+S + E+ L L Sbjct: 1235 NREGGDQAFQKLKKLVAKLESDKKMKEKEYEDERDLKNKLDAQKKLSQA--ELDGLKNAL 1292 Query: 565 HHLSQKVAELEEEKGNLQLHLVDY----DSGRMIESDVYKKMIEMENLAETRLKAISLLE 620 +++ + E+ + +L+ L + + G+ S++ KK E+ E + Sbjct: 1293 EEMAKNRSREEKNRKDLENRLRELEDQAEDGQAARSNLEKKFRGFEDNLEDH-------Q 1345 Query: 621 SQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELAL 680 SQ ++ ++++L ++E +L + + ++ +E + V EE++ L EL L Sbjct: 1346 SQVDEVQDDVNVLSAAKKKLESELEALKRSLDNE--AEGRKV-AEEKMKVLDTELHELQL 1402 Query: 681 VIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKIN 740 + N + L +K ++++ ED+ + +N +E + DK K + ++ EL + Sbjct: 1403 ALSNAENKNTGLVRNVKKVQDEVEDLNEQYENASKE-LSKLDKGNKKTEAELKELRRHVQ 1461 Query: 741 HEEQSKIQTQFGI---DAKIQERDLYIENIESELSKYKSRICRLEESIAVMED------- 790 + S + + ++ E +E++E++ S + +L+ + +ED Sbjct: 1462 ESQSSLDAGELKLRHTQDELDELHHQLEDLEAKSSSLERSKKQLQLQVDDLEDTHEEELA 1521 Query: 791 RRYSLERKADQLGSYLQEKQ--KAYSEYTIQEDELVNRLAV-LMDHDRVVEKQLLEIEHE 847 R ER L + L E Q + SE +Q ++ + L V L+D + ++Q Sbjct: 1522 ARTKAERLVKDLEADLAELQETRVESEPLMQAEKALKSLEVELVDLKKDADRQ----SQA 1577 Query: 848 NKELQKKNQILLEENQNLQISLSDMQQHY-NA-LVEKANRTDLAE--SESTKYQTQLRDL 903 +++ + + L E ++LQ L + ++ NA +K TDL E S+ K + L Sbjct: 1578 FAKVENERRSALREYEDLQAQLDETSKNLANADRAKKKLNTDLDEQLSKLEKASNAQKSL 1637 Query: 904 ESNLKRITHEHQTLIVQKKKE---IEDLEIEFNTQIESAIRDKKVLNEKYEKNIE-YVTQ 959 E LK+ + + + D E+ +A+RD + E V Sbjct: 1638 EKRLKKAEKDLAAAKAASARAGGGVSDEELRRAQAELAALRDDADRERSNKLTAEKRVKN 1697 Query: 960 LEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQ-KQQTQSPDYTEQYINEIN-----K 1013 L+A++++ K +E+ + E LN+ N L + + ++Q ++ + Y+ EI + Sbjct: 1698 LQAEIEDLKEMLEDEKTSKEALNRNNKSLEQELEELREQLEAEEEALNYLEEIKHKKDLE 1757 Query: 1014 LNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLD 1073 +N L KQ D E A K + V+D + L + E E ++ Q + Sbjct: 1758 INELRKQLDAESEA-RDKFEQLKNELERDVADAKHNLEAEKKSRTDAEREAKKAEAQYDE 1816 Query: 1074 SKQHNEE----LQILVREQDDQIKE---LKETKLTFEMNIPKTEGMI--ISSTIEPMSDD 1124 K +E L +E+ +KE L+E E + E + ++ +++ Sbjct: 1817 LKHRSEASDRGKDKLEKERKRALKELRLLREKVEAIEAEKDEQERLAWKFQEEVDALTEA 1876 Query: 1125 ANNVDXXXXXXXXXXXXLKVQEE------EEFIQERSVLQEQSAKLNTELQECYTKIIQL 1178 + L+VQ E E+ + +S + +++L E+++ ++ + Sbjct: 1877 LDLEHKARVAHEKIAKQLRVQLEDFKETAEDATRGKSRADQLTSELQAEIEDLKDQLDEE 1936 Query: 1179 ETLNTELTGHDVVNQEQINQLKSKLE--------------QLNTENDNLLSTVAELRSS- 1223 E N EL + N+ I LK L+ QL +N+ L + E R S Sbjct: 1937 EERNRELANFKINNKSAIADLKKALDREISAREALEEAKRQLERDNNELRDQLDEERVSR 1996 Query: 1224 -ISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEE 1282 S ++ F E L A K E R + + + +QL D + E+ Sbjct: 1997 GNSERAARKSFAELEDTNARLNALNASIGKLEKAKRRAEADYRASKKQLADLQKKEATED 2056 Query: 1283 TNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEI 1327 + + +V L+++L D+++ + + +I LR E+ Sbjct: 2057 SLRAQLEAEVRRLKSRLVDEQDRAADAESDRRRAEVEINKLRDEV 2101 Score = 107 bits (256), Expect = 3e-21 Identities = 183/996 (18%), Positives = 410/996 (41%), Gaps = 95/996 (9%) Query: 654 QVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNY 713 +V +IK V + ++ K + ++ +KE+ +K+LE M L+ Sbjct: 837 KVKKDIKRVDWDAELSKADLDKNAALKELARIQAEKERTEFQLKELEGTIGSFMENLRGA 896 Query: 714 IQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSK 773 ++ ++ DK + E+ + L +++S++ G I D + +++ + + Sbjct: 897 EKQLHEIQDKYHALDEERTT--LRNSMSKKESELDLLRG---DISTGDSKLRDLKRQCDE 951 Query: 774 YKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRL------ 827 + ++ LE + + E + + + L+ +++ S+Y +Q L+ L Sbjct: 952 SEKKLKELEADAGKKKSEKAKQETEIASISASLESEKETNSKYQLQVRNLLRNLEEEKED 1011 Query: 828 AVLMDHD-----RVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEK 882 +D + R ++ LE++ EL + ++ +N+ +++ L + Sbjct: 1012 MARLDEEIANLQRFKDRLSLELDDLEDELDEYTKVKQAAEKNISALNDQLKETKRELETE 1071 Query: 883 ANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRD 942 + +E+ + KYQ ++ +L+ NL+R + T+ + K ++ E N Q E Sbjct: 1072 SAARGASEANNKKYQEKIGELKGNLQREIGSNTTM-DKNNKALQGNISELNDQTEDENNK 1130 Query: 943 KKVLNEKYEK---NIEYV------------------TQLEAQLQEYKNNIENLNMNVEEL 981 KK L+ + +K ++ V T+LEA + + K ++ + +L Sbjct: 1131 KKTLSNQLKKVGDDLADVRSHIDDEHNQKLRLTNENTRLEAAIDDLKRQLDETKGKISKL 1190 Query: 982 NKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLK-----------------QKDEE 1024 K +L KH++ Q D E +++ K N LK QK ++ Sbjct: 1191 EKEKQQL-QKHLEDVTAQFED-AENKFSQLTKTNLKLKADLDELQDNREGGDQAFQKLKK 1248 Query: 1025 IIALNQKINNAQVSYMSMVSDYESKL-AQ---FTTKLENMEEEMQRVSKQLLDSKQHNEE 1080 ++A + + D ++KL AQ +L+ ++ ++ ++K +++ ++ Sbjct: 1249 LVAKLESDKKMKEKEYEDERDLKNKLDAQKKLSQAELDGLKNALEEMAKNRSREEKNRKD 1308 Query: 1081 LQILVREQDDQIKELKETKLTFEMNIPKTEGMI--ISSTIEPMSDDANNVDXXXXXXXXX 1138 L+ +RE +DQ ++ + + E E + S ++ + DD N + Sbjct: 1309 LENRLRELEDQAEDGQAARSNLEKKFRGFEDNLEDHQSQVDEVQDDVNVLSAAKKKLESE 1368 Query: 1139 XXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQ 1198 LK + E + R V +E+ L+TEL E + E NT L + + Sbjct: 1369 LEALKRSLDNE-AEGRKVAEEKMKVLDTELHELQLALSNAENKNTGLV-------RNVKK 1420 Query: 1199 LKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELR 1258 ++ ++E LN + +N ++ S + + E+ EL ++H+ + ++ E +LR Sbjct: 1421 VQDEVEDLNEQYEN----ASKELSKLDKGNKKTEAELKEL-RRHVQESQSSLDAGELKLR 1475 Query: 1259 VQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVIN 1318 + + QL D S+ E +K +Q+ + L+D E + K ++ Sbjct: 1476 HTQDELDELHHQLEDLEAKSSSLERSK----KQLQLQVDDLEDTHEEELAARTKAERLVK 1531 Query: 1319 QIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLK 1378 +E +E+++ +V + + + +Q Q + + NE + L+ Sbjct: 1532 DLEADLAELQETRVESEPLMQAEKALKSLEVELVDLKKDADRQSQAFAKVE-NERRSALR 1590 Query: 1379 KSSXXXXXXXXXXXXRVNDAEAKV---LELTHQL-ELKDSEIYQKTHEYTITLTQRNDEF 1434 + N AK +L QL +L+ + QK+ E + +++ Sbjct: 1591 EYEDLQAQLDETSKNLANADRAKKKLNTDLDEQLSKLEKASNAQKSLEKRLKKAEKDLAA 1650 Query: 1435 ENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVK 1494 E+L ++ELA LR ++ T +K + + + IE+L Sbjct: 1651 AKAASARAGGGVSDEELR-RAQAELAALRDDADRERSNKLTAEKRVKNLQAE-IEDLKEM 1708 Query: 1495 ITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKI 1554 + + + + + NK+LE+E+ E++ LE +E E + +EI + +++ +++ Sbjct: 1709 LEDEKTSKEALNRNNKSLEQEL---EELREQLEAEE-EALNYLEEIKHKKDL---EINEL 1761 Query: 1555 QKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELD 1590 +K + S+ + + EQL N + +++ DA E + Sbjct: 1762 RKQLDAESEARD-KFEQLKNELERDVADAKHNLEAE 1796 >UniRef50_Q24GP7 Cluster: Putative uncharacterized protein; n=2; cellular organisms|Rep: Putative uncharacterized protein - Tetrahymena thermophila SB210 Length = 2929 Score = 124 bits (299), Expect = 2e-26 Identities = 272/1356 (20%), Positives = 579/1356 (42%), Gaps = 141/1356 (10%) Query: 302 PSC---EEKTEIEEK-GSLEIANMTELTKKIELLEHLNCQIRQTNKEL--ENKLATMGTE 355 P C EEK+ ++ K +E+ E K + + +N TNK N +AT Sbjct: 249 PDCIIVEEKSTLKPKQAEVEMCIEIEANPKDLIQQKMN---NSTNKSYFSNNSIAT---- 301 Query: 356 SKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQ-LSSETLNQDTDKKINKNE---IAKLE 411 K + S K S + S S N S K ++ T NQ T K +NE I +LE Sbjct: 302 PKHLESSLKMDSSIKSNTSSINKLSSNKEENKNGPNTITNNQTTSKIFQENEKQGIIQLE 361 Query: 412 MVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTN 471 +Q N + D+ V K I + Q + P I + Sbjct: 362 NNLQKSNCQIKDQTNVNDLIANQSINSENLQSVKSLEIQNQGKQEDQFQDKPKQISDNNS 421 Query: 472 TEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKL-KSAEEQITQLNDEIDAA---NKNMI 527 T N + Q Q+ ND +K +IE + S+E ++Q+N + ++ ++ + Sbjct: 422 TSINNYDLSSKFQQNQKQNDILK------IIENIPSSSESDLSQINSQPNSQQTQDQQLF 475 Query: 528 KVKS------NHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNL 581 K ++ NH+ + Q ++ D+ + + +Q+ + EEK N Sbjct: 476 KQETKAIYDINHQSPILQQKQIQDDIISNKQFKNDQNNQNNGDKYETQEDQFVFEEK-NP 534 Query: 582 QLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKY-DEV 640 Q L + +I D +K+ ++N + ++ +QK++L Q Q K DE Sbjct: 535 QNELNETKQQNIISEDNLQKLNSIQNSDLNLSQNLNKNSAQKYELNQTAVESQLKIIDED 594 Query: 641 EDKLADISQLQ-----SDQVCSEI-KSVHLEEQIDALSASKKELA----LVIENLKLDKE 690 + D+++ Q S + EI K+ H E++ +A +++EL LV EN + K+ Sbjct: 595 QYVNKDLNEQQQIIQTSQNIDEEINKTNHFEQESNAQQNNQEELKNESQLVQEN-NITKQ 653 Query: 691 QLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQ 750 + L++++ +++ YIQ+ +++ +S +K E + +Q+ QTQ Sbjct: 654 IISNQFSQLQSNQVKSTSQISQYIQQ------EIQPLSLQKSEEQ----SSFQQNLTQTQ 703 Query: 751 FGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQ-LGSYLQEK 809 + E++ ++ + +LS+ + R+EE E+ +E + Q + L EK Sbjct: 704 QNQNEISLEKESSKQSAQ-KLSQLLDTLDRMEEE----EENEQKIETETIQNQNNILNEK 758 Query: 810 QKAYSEYTIQEDELVNRLAVLMDH--------DRVVEKQLLEIEHENKELQKKNQILLEE 861 + ++ +++E + A MD+ D ++ Q + N L+ KNQ+ +EE Sbjct: 759 EITNAQMDEEKEEEIRGQANQMDNLFQNNPNQDDLLIDQQISNNQTNISLESKNQVQIEE 818 Query: 862 NQ-----NLQISLSDMQQHYNALVEK---ANRTDLAESES-TKYQTQLRDLESNLKRIT- 911 +Q + D +Q N VEK +N++ L + +S TK Q+ + E K I Sbjct: 819 SQMKPETSQSFKQEDTEQD-NKSVEKLIASNKSSLQKDQSLTKVINQIEECEKLDKIIDE 877 Query: 912 HEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNI 971 ++ + +++I IE N ++++ N+ + + ++ + +Q++E++ + Sbjct: 878 NDEENQSKTNQQQIITESIEKNQNEKNSMEKFNDSNKSSLQKDKSLSSILSQIEEFEK-M 936 Query: 972 ENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNA-LLKQKDEEI--IAL 1028 E+ + EE+ ++ +D Q+ ++ E++K N LL+Q+ + + + Sbjct: 937 EDEDEK-EEIQVSKIDQLDHFKNNNLLQNIQMDQEKEIEMSKNNQQLLEQQSTQNNQLDI 995 Query: 1029 NQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQ 1088 N+K +N ++Y ++ Q L++ +EE+++ +Q Q+N++L V+E Sbjct: 996 NEKTSNQ--------NEYNQQIDQ--NNLQSQKEELKQQDQQTFIENQNNQQLNE-VQES 1044 Query: 1089 DDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEE 1148 + Q ++ EMN+ K +I++ + + + QE+ Sbjct: 1045 NSQ------QEIQIEMNL-KDNNQVINNLQNDIQPKDEQSEIKTCQIQDNDKEINQQEQH 1097 Query: 1149 EFIQE--RSVLQEQSAKLNTELQEC-YTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQ 1205 + + + + S+ + + QE + + + LN + + EQ N + + Sbjct: 1098 QINSQLLKIIDDSSSSSQSNDSQEVNFQQNEHQQILNIQNENQQLDQIEQENLINDSDQL 1157 Query: 1206 LNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFE 1265 + ND + +T + I + + + E Q ++ + +T+++ Q S + Sbjct: 1158 VEVSNDKVQNTFEQQNEQIQNINHNQLNQFEEYAIQDQNNKQIENIETQNQ---QNSLVQ 1214 Query: 1266 SKYEQLLD-SVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILR 1324 EQ+ + +V + + N + EQ+ +NK Q+ E L + Q + Q++IL Sbjct: 1215 ENLEQITELNVNINQINQHNLLKQTEQIE--ENKEQNDIEQL-DFQNDEQQIYTQVDILS 1271 Query: 1325 SEIEDE-KVAFXXXXXXXXXXXXXXXXDLRTE-------------NQSYKQMQEQSILNI 1370 E+ E + +L+ + QS + ++QSIL + Sbjct: 1272 KEVASENQQQSNEKQQIQVEEKEQQITELKDQLPEINKHEIIEVNQQSIHEQEQQSIL-M 1330 Query: 1371 NEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQR 1430 ++ ++ +V DA+ ++ EL Q++++D +I + IT Q+ Sbjct: 1331 QKQQQYVEAKEQQTTQSEVNRYLQV-DAKQQISELKQQIQVEDEQIVDQVSSQ-IT-EQK 1387 Query: 1431 NDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIER--VKLI 1488 N + +++Q + ++I+++ E + ++I + K +N YE Q E EIE+ ++ Sbjct: 1388 NQQQSQIQEQY--HVEQIQNIV-ENDQSISIDQ-KQQQNCV-YEVQQLEQEIEQQGKEID 1442 Query: 1489 EELNVKIT-ESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMV 1547 E+ +++ +S+ LN Q+ E K L++ + + Q + Q +I +E+ Q ++ Sbjct: 1443 EQQQQQVSQQSIQLNTQIQEEEKLLQQSHIEEDLQQKLIVEQNQQIFQCVNEVQQQQKVI 1502 Query: 1548 -RASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLD 1582 +++ + S ++ + E+ ++L+D Sbjct: 1503 DDKQQESVEQSLHEQSAQQREQKEEFSEPSKQQLID 1538 Score = 119 bits (287), Expect = 6e-25 Identities = 244/1314 (18%), Positives = 546/1314 (41%), Gaps = 111/1314 (8%) Query: 297 KQSIEPSCEEKTEIEEKGSLEIA-NMTELTKKIELLEHLNCQIRQTNKELENKLATMGTE 355 ++ +E ++ E+++ +++ + KK E L+ I+ N ++ + T + Sbjct: 39 REKLEQQLKKAKELQKLAQIDLEITKKDSVKKDEPAPTLSTNIQ--NPTAQSSVTTTPSS 96 Query: 356 SKA-----VSSPSKKGSPLISRKSGRNTASKMKSPWSQLSS--ETLNQDTDKKINKNEIA 408 ++ VSS S + S ++ R +N S + +P S S+ TL T+ K + + Sbjct: 97 NQVPSVSMVSSFSSRFSSILQRD--QNKTSLINTPLSTTSTAPSTLPAITENKFSAIS-S 153 Query: 409 KLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXX------GKDTLIAQLQLEHQQHMEG 462 +L + +SLN+ L + E + + K ++ L LE+ + Sbjct: 154 RLSQLRESLNQTLSNSEIKLPSQPVSQNNRETKSEIRDFSDNKQSINKSLLLENNKQTHD 213 Query: 463 PSLIHVGT-------NTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQL 515 S+ + + ++ D N++ +Q + ++ N + V K + K K AE ++ Sbjct: 214 SSITSIISKIKSNIQSSTDTNQVGNLQIKKNEDNNPDCIIVEEKSTL-KPKQAE---VEM 269 Query: 516 NDEIDAANKNMIKVKSNHKLKLKQMQK-TIDNFSKVSDSNKEIVRLTEELHHLSQKVAEL 574 EI+A K++I+ K N+ +I + S K + +++ + Sbjct: 270 CIEIEANPKDLIQQKMNNSTNKSYFSNNSIATPKHLESSLKMDSSIKSNTSSINKLSSNK 329 Query: 575 EEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAE---------TRLKAISLLESQKFD 625 EE K + + ++ + + + +I++EN + T + + +S + Sbjct: 330 EENKNGPNTITNNQTTSKIFQENEKQGIIQLENNLQKSNCQIKDQTNVNDLIANQSINSE 389 Query: 626 LVQELHILQ-QKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIEN 684 +Q + L+ Q + ED+ D + SD + I + L + + + ++ +IEN Sbjct: 390 NLQSVKSLEIQNQGKQEDQFQDKPKQISDNNSTSINNYDLSSKFQQ-NQKQNDILKIIEN 448 Query: 685 LKLDKEQLYGTIKDLENDKEDIMNKL-QNYIQENMDLTDKLEKMSAEKISELLAKINHEE 743 + E I N ++ +L + + D+ + + ++I + + + Sbjct: 449 IPSSSESDLSQINSQPNSQQTQDQQLFKQETKAIYDINHQSPILQQKQIQDDIISNKQFK 508 Query: 744 QSKIQTQFGIDAKIQERDLYIE--NIESELSKYKSRICRLEESIAVMEDRRYSLERKADQ 801 + G + QE E N ++EL++ K + E+++ + S++ Sbjct: 509 NDQNNQNNGDKYETQEDQFVFEEKNPQNELNETKQQNIISEDNLQKLN----SIQNSDLN 564 Query: 802 LGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLE-------IEHENKELQKK 854 L L + +Y + + + ++L ++ D D+ V K L E ++ ++E+ K Sbjct: 565 LSQNLNKNSA--QKYELNQTAVESQLKII-DEDQYVNKDLNEQQQIIQTSQNIDEEINKT 621 Query: 855 NQILLEENQNLQISLSDMQQHYNALVEKANRT-DLAESESTKYQT-QLRDLESNLKRITH 912 N E+ N Q + + ++ + LV++ N T + ++ ++ Q+ Q++ + I Sbjct: 622 NHF--EQESNAQQNNQEELKNESQLVQENNITKQIISNQFSQLQSNQVKSTSQISQYIQQ 679 Query: 913 EHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIE 972 E Q L +QK +E + TQ + + + E +++ + ++QL L + E Sbjct: 680 EIQPLSLQKSEEQSSFQQNL-TQTQQNQNEISLEKESSKQSAQKLSQLLDTLDRMEEEEE 738 Query: 973 N-LNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQK-DEEIIALNQ 1030 N + E + N L +K + Q + E+ + N+++ L + +++ + ++Q Sbjct: 739 NEQKIETETIQNQNNILNEKEITNAQMDE-EKEEEIRGQANQMDNLFQNNPNQDDLLIDQ 797 Query: 1031 KINNAQVSYM----SMVSDYESKLAQFTT---KLENMEEEMQRVSKQLLDSKQHNEELQI 1083 +I+N Q + + V ES++ T+ K E+ E++ + V K + +K ++ Q Sbjct: 798 QISNNQTNISLESKNQVQIEESQMKPETSQSFKQEDTEQDNKSVEKLIASNKSSLQKDQS 857 Query: 1084 LVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLK 1143 L + + QI+E ++ + N + + I S + N + Sbjct: 858 LTKVIN-QIEECEKLDKIIDENDEENQSKTNQQQIITESIEKNQNEKNSMEKFNDSNKSS 916 Query: 1144 VQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKL 1203 +Q+++ S ++E K+ E ++ ++ +++ L+ ++++ Q++Q K Sbjct: 917 LQKDKSLSSILSQIEEFE-KMEDEDEKEEIQVSKIDQLD-HFKNNNLLQNIQMDQEKEI- 973 Query: 1204 EQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSA 1263 +++ N LL + + + ++++ E + Q + Q QK E + + Q + Sbjct: 974 -EMSKNNQQLLEQQSTQNNQLD--INEKTSNQNE-YNQQIDQNNLQSQKEELKQQDQQTF 1029 Query: 1264 FESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEIL 1323 E++ Q L+ VQ S + Q ++ L+D + + NLQ Q EI Sbjct: 1030 IENQNNQQLNEVQESNSQ---------QEIQIEMNLKDNNQVINNLQNDIQPKDEQSEIK 1080 Query: 1324 RSEIED-EKVAFXXXXXXXXXXXXXXXXDLRTENQS-------YKQMQEQSILNINEENA 1375 +I+D +K D + +QS ++Q + Q ILNI EN Sbjct: 1081 TCQIQDNDKEINQQEQHQINSQLLKIIDDSSSSSQSNDSQEVNFQQNEHQQILNIQNENQ 1140 Query: 1376 QLKKSSXXXXXXXXXXXXRV-NDAEAKVLE-LTHQLELKDSEIYQKTHEYTITLTQRNDE 1433 QL + V ND E Q++ + + EY I Q N + Sbjct: 1141 QLDQIEQENLINDSDQLVEVSNDKVQNTFEQQNEQIQNINHNQLNQFEEYAIQ-DQNNKQ 1199 Query: 1434 FENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNV 1493 EN +E + + L E ++ L + +++ N + +++ +IE K E+ ++ Sbjct: 1200 IEN-----IETQNQQNSLVQENLEQITELNVNINQ-INQHNLLKQTEQIEENK--EQNDI 1251 Query: 1494 KITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMV 1547 + + + +Q+ L +EVA N+ Q+ E Q+I++ +IT L++ + Sbjct: 1252 EQLDFQNDEQQIYTQVDILSKEVASENQQQSN-EKQQIQVEEKEQQITELKDQL 1304 Score = 99 bits (238), Expect = 5e-19 Identities = 196/1043 (18%), Positives = 441/1043 (42%), Gaps = 100/1043 (9%) Query: 298 QSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESK 357 Q+I+ + E++ + + N EL + +L++ N + + + + + Sbjct: 612 QNIDEEINKTNHFEQESNAQQNNQEELKNESQLVQENNITKQIISNQFSQLQSNQVKSTS 671 Query: 358 AVSSPSKKG-SPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQS 416 +S ++ PL +KS ++ + +Q + ++ +K+ +K KL ++ + Sbjct: 672 QISQYIQQEIQPLSLQKSEEQSSFQQNLTQTQQNQNEIS--LEKESSKQSAQKLSQLLDT 729 Query: 417 LNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPS--LIHVGTNTED 474 L++ ++E + K+ AQ+ E ++ + G + + ++ N + Sbjct: 730 LDRMEEEEENEQKIETETIQNQNNILNEKEITNAQMDEEKEEEIRGQANQMDNLFQNNPN 789 Query: 475 VNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHK 534 +++ Q+ + N ++ N + E E + ++ + NK++ K+ +++K Sbjct: 790 QDDLLIDQQISNNQTNISLESKNQVQIEESQMKPETSQSFKQEDTEQDNKSVEKLIASNK 849 Query: 535 LKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMI 594 L++ Q + +KV + +E E+L + + E + K N Q + + Sbjct: 850 SSLQKDQ----SLTKVINQIEEC----EKLDKIIDENDEENQSKTNQQQIITESIEKNQN 901 Query: 595 ESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQ 654 E + +K + + + K++S + SQ ++E ++ + ++ E +++ I QL + Sbjct: 902 EKNSMEKFNDSNKSSLQKDKSLSSILSQ----IEEFEKMEDEDEKEEIQVSKIDQLDHFK 957 Query: 655 VCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYI 714 + ++++ ++++ + + SK L +E QL D+ N+K N+ I Sbjct: 958 NNNLLQNIQMDQEKE-IEMSKNNQQL-LEQQSTQNNQL-----DI-NEKTSNQNEYNQQI 1009 Query: 715 QENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKY 774 +N +L + E++ + + N+++ +++Q + +IQ IE L Sbjct: 1010 DQN-NLQSQKEELKQQDQQTFIENQNNQQLNEVQ-ESNSQQEIQ--------IEMNLKDN 1059 Query: 775 KSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHD 834 I L+ I +++ E K Q+ Q+ K ++ QE +N + + D Sbjct: 1060 NQVINNLQNDIQPKDEQS---EIKTCQI----QDNDKEINQ---QEQHQINSQLLKIIDD 1109 Query: 835 RVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESEST 894 Q + + N + + QIL +N+N Q+ + + N + L E + Sbjct: 1110 SSSSSQSNDSQEVNFQQNEHQQILNIQNENQQLDQIEQENLIN------DSDQLVEVSND 1163 Query: 895 KYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNI 954 K Q ++ I H + N E AI+D+ N K +NI Sbjct: 1164 KVQNTFEQQNEQIQNINHN-----------------QLNQFEEYAIQDQ---NNKQIENI 1203 Query: 955 EYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKL 1014 E Q + +QE I LN+N+ ++N+ NL + +++ + Q+ + N+ ++ Sbjct: 1204 ETQNQQNSLVQENLEQITELNVNINQINQHNLLKQTEQIEENKEQNDIEQLDFQNDEQQI 1263 Query: 1015 NALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKL-ENMEEEMQRVSKQLLD 1073 + +E+ + NQ+ +N + V + E ++ + +L E + E+ V++Q + Sbjct: 1264 YTQVDILSKEVASENQQQSNEK--QQIQVEEKEQQITELKDQLPEINKHEIIEVNQQSI- 1320 Query: 1074 SKQHNEELQILVREQDDQIKELKETKLT-FEMN--IPKTEGMIISSTIEPMS-DDANNVD 1129 H +E Q ++ ++ Q E KE + T E+N + IS + + +D VD Sbjct: 1321 ---HEQEQQSILMQKQQQYVEAKEQQTTQSEVNRYLQVDAKQQISELKQQIQVEDEQIVD 1377 Query: 1130 XXXXXXXXXXXXLKVQEEEEFIQER---SVLQEQSAKLNTELQE-CYTKIIQLETLNTEL 1185 + Q +E++ E+ V +QS ++ + Q+ C ++ QLE E Sbjct: 1378 QVSSQITEQKNQQQSQIQEQYHVEQIQNIVENDQSISIDQKQQQNCVYEVQQLEQ-EIEQ 1436 Query: 1186 TGHDVVNQEQINQLKSKLEQLNT---ENDNLL--STVAE-LRSSISSAVDQRGFEIAELW 1239 G ++ Q+Q Q+ + QLNT E + LL S + E L+ + +Q+ F+ Sbjct: 1437 QGKEIDEQQQ-QQVSQQSIQLNTQIQEEEKLLQQSHIEEDLQQKLIVEQNQQIFQCVNEV 1495 Query: 1240 KQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKL 1299 +Q Q+ D ++ E V+ S E +Q + + ++ +++ + +Q + Sbjct: 1496 QQQ--QKVIDDKQQE---SVEQSLHEQSAQQ-REQKEEFSEPSKQQLIDQQASQKIQGEE 1549 Query: 1300 QDKEEHLRNLQEKYADVINQIEI 1322 + ++ + E D NQ+EI Sbjct: 1550 KQQKIEENDKSELVIDTSNQLEI 1572 Score = 91.5 bits (217), Expect = 2e-16 Identities = 194/982 (19%), Positives = 435/982 (44%), Gaps = 111/982 (11%) Query: 389 LSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTL 448 L + ++Q+ + +++KN LE QS + +D I+EK T ++ L Sbjct: 962 LQNIQMDQEKEIEMSKNNQQLLEQ--QSTQNNQLD----INEK-TSNQNEYNQQIDQNNL 1014 Query: 449 IAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVN--VKDLIEKLK 506 Q Q E + + + I N + +NE+ + Q + ++ +KD N + +L ++ Sbjct: 1015 --QSQKEELKQQDQQTFIE-NQNNQQLNEVQESNSQQEIQIEMNLKDNNQVINNLQNDIQ 1071 Query: 507 SAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSN-KEIVRLTEELH 565 +EQ +I +K I + H++ Q+ K ID+ S S SN + V + H Sbjct: 1072 PKDEQSEIKTCQIQDNDKE-INQQEQHQIN-SQLLKIIDDSSSSSQSNDSQEVNFQQNEH 1129 Query: 566 HLSQKVAELEEEKGNLQLHLVDYDSGRMIE--SDVYKKMIE-----MENLAETRLKAIS- 617 + ++ ++ + DS +++E +D + E ++N+ +L Sbjct: 1130 QQILNIQNENQQLDQIEQENLINDSDQLVEVSNDKVQNTFEQQNEQIQNINHNQLNQFEE 1189 Query: 618 -LLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKK 676 ++ Q ++ + Q+ V++ L I++L + ++I +L +Q + + +K+ Sbjct: 1190 YAIQDQNNKQIENIETQNQQNSLVQENLEQITELNVN--INQINQHNLLKQTEQIEENKE 1247 Query: 677 ELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELL 736 + + + + D++Q+Y + D+ + + N+ Q+ ++ + + +K ++++ ++ + L Sbjct: 1248 QNDIEQLDFQNDEQQIYTQV-DILSKEVASENQQQSNEKQQIQVEEKEQQIT--ELKDQL 1304 Query: 737 AKINHEE-----QSKIQTQFGIDAKIQERDLYIE-----NIESELSKY-----KSRICRL 781 +IN E Q I Q +Q++ Y+E +SE+++Y K +I L Sbjct: 1305 PEINKHEIIEVNQQSIHEQEQQSILMQKQQQYVEAKEQQTTQSEVNRYLQVDAKQQISEL 1364 Query: 782 EESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQL 841 ++ I V ED E+ DQ+ S + E QK + IQE V ++ ++++D+ + Sbjct: 1365 KQQIQV-ED-----EQIVDQVSSQITE-QKNQQQSQIQEQYHVEQIQNIVENDQSISIDQ 1417 Query: 842 LEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLR 901 + ++ E+Q+ Q + E Q +I QQ ++ T + E E Q+ + Sbjct: 1418 KQQQNCVYEVQQLEQEI--EQQGKEIDEQQQQQVSQQSIQL--NTQIQEEEKLLQQSHIE 1473 Query: 902 DLESNLKRITHEHQTL------IVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIE 955 + + K I ++Q + + Q++K I+D + E +E ++ ++ + ++ Sbjct: 1474 E-DLQQKLIVEQNQQIFQCVNEVQQQQKVIDDKQQE---SVEQSLHEQSAQQREQKEEFS 1529 Query: 956 YVT--QLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINK 1013 + QL Q K E +EE +K L +ID Q + + T ++ + Sbjct: 1530 EPSKQQLIDQQASQKIQGEEKQQKIEENDKSEL-VIDTSNQLEIQEEKQVTSIIKHDEDC 1588 Query: 1014 LNALLKQKD-EEIIAL-NQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQL 1071 + LL+ ++ ++++ + N+K + ++ + +++ + N E + Q Sbjct: 1589 KHILLQSEEIQQVVDISNEKDDPTHQTFSNNLNNIVIEQQNEQILNSNQIEAKSDQNHQQ 1648 Query: 1072 LDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXX 1131 +DSK + QIL+ ++QIK ++E K++ M S IE +++ N+ D Sbjct: 1649 IDSKFQADGEQILLSNSNNQIK-IQE----------KSDDM---SQIEVENENNNHED-- 1692 Query: 1132 XXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKII-QLETLNTELTGHDV 1190 ++E+ ++ + + EQ LN Q+ + +I+ Q + ++ D Sbjct: 1693 --------------QQEDAMEIETQIDEQPDHLN---QDQFDQILDQNQQKESQYNNDDK 1735 Query: 1191 VNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADF 1250 + Q+ + K Q+ N ++L + + + +I D + +L K+ ++E Sbjct: 1736 IKQQDSPKTKETEWQI-PNNLDILDYINQ-KQTIQKESDYQKISDVDL-KKEFDEKEYSA 1792 Query: 1251 QKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQ 1310 + + L E K Q + + + Q ++I + T++ + + D E+ L+ Q Sbjct: 1793 EFIKKSSPNSLEILEMK--QNISNDKKEEQSYKSEIKLGDANTNIGSVMLDMEKFLK--Q 1848 Query: 1311 EKYADVINQIEILRSEIEDEKV 1332 + +D+ NQ + SEI++E V Sbjct: 1849 KGLSDLKNQSTVPNSEIKNENV 1870 Score = 80.6 bits (190), Expect = 3e-13 Identities = 214/1192 (17%), Positives = 499/1192 (41%), Gaps = 83/1192 (6%) Query: 176 QEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDE 235 QE++ + Q+++ N Q + + + ++E + Sbjct: 635 QEELKNESQLVQENNITKQIISNQFSQLQSNQVKSTSQISQYIQQEIQPLSLQKSEEQSS 694 Query: 236 KQRLLKDIESKDVRISSLEEANKLLEAARFEI--SLEHSKLAQELEQXXXXXXXXXXXXX 293 Q+ L + IS +E++K ++ +L+ + +E EQ Sbjct: 695 FQQNLTQTQQNQNEISLEKESSKQSAQKLSQLLDTLDRMEEEEENEQKIETETIQNQNNI 754 Query: 294 XLAKQSIEPSCEEKTEIEEKGSL-EIANMTELT-KKIELLEHLNCQIRQTNKELENKLAT 351 K+ +E+ E E +G ++ N+ + + +LL QTN LE+K Sbjct: 755 LNEKEITNAQMDEEKEEEIRGQANQMDNLFQNNPNQDDLLIDQQISNNQTNISLESKNQV 814 Query: 352 MGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINK-NEIAKL 410 ES+ S+ + + ++ + S S L + Q K IN+ E KL Sbjct: 815 QIEESQMKPETSQSFKQEDTEQDNKSVEKLIASNKSSLQKD---QSLTKVINQIEECEKL 871 Query: 411 EMVIQSL---NKDLVDKEYVISEK-DTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLI 466 + +I N+ +++ +I+E + D+ + LQ + + S I Sbjct: 872 DKIIDENDEENQSKTNQQQIITESIEKNQNEKNSMEKFNDSNKSSLQKD-KSLSSILSQI 930 Query: 467 HVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEI---DAAN 523 ED +E ++Q +L D K+ N+ I+ + E ++++ N ++ + Sbjct: 931 EEFEKMEDEDEKEEIQVSKIDQL-DHFKNNNLLQNIQMDQEKEIEMSKNNQQLLEQQSTQ 989 Query: 524 KNMIKV--KSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGN- 580 N + + K++++ + Q Q +N + K+ + T + +Q++ E++E Sbjct: 990 NNQLDINEKTSNQNEYNQ-QIDQNNLQSQKEELKQQDQQTFIENQNNQQLNEVQESNSQQ 1048 Query: 581 -LQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDE 639 +Q+ + D+ ++I + + I+ ++ ++ +K + ++ K QE H + + + Sbjct: 1049 EIQIEMNLKDNNQVINN--LQNDIQPKD-EQSEIKTCQIQDNDKEINQQEQHQINSQLLK 1105 Query: 640 VEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVI-ENLKLDKEQLYGTIKD 698 + D + SQ Q + ++ H +QI + ++L + ENL D +QL D Sbjct: 1106 IIDDSSSSSQSNDSQEVNFQQNEH--QQILNIQNENQQLDQIEQENLINDSDQLVEVSND 1163 Query: 699 -LENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKI 757 ++N E ++QN I N L E ++ ++ + I + Q Q ++ +I Sbjct: 1164 KVQNTFEQQNEQIQN-INHNQ-LNQFEEYAIQDQNNKQIENIETQNQQNSLVQENLE-QI 1220 Query: 758 QERDLYIENI-ESELSKYKSRICRLEESIAV----MEDRRYSLERKADQLGSYL--QEKQ 810 E ++ I I + L K +I +E + ++ + + D L + + +Q Sbjct: 1221 TELNVNINQINQHNLLKQTEQIEENKEQNDIEQLDFQNDEQQIYTQVDILSKEVASENQQ 1280 Query: 811 KAYSEYTIQEDELVNRLAVLMDHDRVVEK-QLLEIEHENKELQKKNQILLEENQNLQISL 869 ++ + IQ +E ++ L D + K +++E+ ++ Q++ IL+++ Q Q Sbjct: 1281 QSNEKQQIQVEEKEQQITELKDQLPEINKHEIIEVNQQSIHEQEQQSILMQKQQ--QYVE 1338 Query: 870 SDMQQHYNALVEKANRTDLAESEST-KYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDL 928 + QQ + V + + D + S K Q Q+ D E + +++ + + QK ++ + Sbjct: 1339 AKEQQTTQSEVNRYLQVDAKQQISELKQQIQVED-EQIVDQVSSQ---ITEQKNQQQSQI 1394 Query: 929 EIEFNT-QIESAIR-DKKV-LNEKYEKNIEY-VTQLEAQLQEYKNNIENLNMNVEELNKM 984 + +++ QI++ + D+ + +++K ++N Y V QLE ++++ I+ +++++ Sbjct: 1395 QEQYHVEQIQNIVENDQSISIDQKQQQNCVYEVQQLEQEIEQQGKEIDEQQQ--QQVSQQ 1452 Query: 985 NLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVS 1044 +++L + +Q+++ + +I E + +++Q + +N+ +V Sbjct: 1453 SIQL-NTQIQEEEKL---LQQSHIEEDLQQKLIVEQNQQIFQCVNEVQQQQKVIDDKQQE 1508 Query: 1045 DYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEM 1104 E L + + + +EE SKQ L +Q ++++Q ++Q + + E + Sbjct: 1509 SVEQSLHEQSAQQREQKEEFSEPSKQQLIDQQASQKIQGEEKQQKIEENDKSELVIDTSN 1568 Query: 1105 NIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKL 1164 + E ++S I+ +D ++ ++Q+ + E+ Q+ Sbjct: 1569 QLEIQEEKQVTSIIK-HDEDCKHI---------LLQSEEIQQVVDISNEKDDPTHQT--F 1616 Query: 1165 NTELQECYTKIIQLETLNT-ELTGHDVVNQEQI-NQLKSKLEQLNTENDNLLSTVAELRS 1222 + L + + LN+ ++ N +QI ++ ++ EQ+ N N + E Sbjct: 1617 SNNLNNIVIEQQNEQILNSNQIEAKSDQNHQQIDSKFQADGEQILLSNSNNQIKIQEKSD 1676 Query: 1223 SISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAF-ESKYEQLLDSVQSSTQE 1281 +S E+ H Q+E D + E ++ Q + +++Q+LD Q + Sbjct: 1677 DMSQ------IEVENENNNHEDQQE-DAMEIETQIDEQPDHLNQDQFDQILDQNQQKESQ 1729 Query: 1282 ETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVA 1333 N +Q + K ++ E + N + D INQ + ++ E + +K++ Sbjct: 1730 YNNDDKIKQQDSP---KTKETEWQIPNNLD-ILDYINQKQTIQKESDYQKIS 1777 Score = 56.0 bits (129), Expect = 8e-06 Identities = 197/1083 (18%), Positives = 446/1083 (41%), Gaps = 137/1083 (12%) Query: 160 VLQVKMKIMETTILDLQEKINEKDQIIEAKN-KATTXXXXXXXXXXXXXXXXXEDTKQQM 218 +L ++ + + ++ + IN+ DQ++E N K ++ Sbjct: 1132 ILNIQNENQQLDQIEQENLINDSDQLVEVSNDKVQNTFEQQNEQIQNINHNQLNQFEEYA 1191 Query: 219 TKMQENFIAMEAEWKDEKQRL----LKDIESKDVRISSLEEANKLLEAARFEISLEHSKL 274 + Q N E ++++ L L+ I +V I+ + + N L + + +E +K Sbjct: 1192 IQDQNNKQIENIETQNQQNSLVQENLEQITELNVNINQINQHNLLKQTEQ----IEENKE 1247 Query: 275 AQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHL 334 ++EQ + S E + E + + EK +++ +K + + L Sbjct: 1248 QNDIEQ-LDFQNDEQQIYTQVDILSKEVASENQQQSNEKQQIQV------EEKEQQITEL 1300 Query: 335 NCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETL 394 Q+ + NK +++ + +S ++ S L+ ++ A + ++ S++ + L Sbjct: 1301 KDQLPEINK---HEIIEVNQQS---IHEQEQQSILMQKQQQYVEAKEQQTTQSEV-NRYL 1353 Query: 395 NQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQL 454 D K +I++L+ IQ ++ +VD+ +S + T + + Q+ Sbjct: 1354 QVDA-----KQQISELKQQIQVEDEQIVDQ---VSSQITEQKNQQQSQIQEQYHVEQI-- 1403 Query: 455 EHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQ 514 Q +E I + + N + +VQ QL+QE+ + K+++ + + + + + TQ Sbjct: 1404 --QNIVENDQSISIDQKQQQ-NCVYEVQ-QLEQEIEQQGKEIDEQQQQQVSQQSIQLNTQ 1459 Query: 515 LNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEI-----VRLTEELHHLSQ 569 + +E ++ I+ KL ++Q Q+ ++V K I + + LH S Sbjct: 1460 IQEEEKLLQQSHIEEDLQQKLIVEQNQQIFQCVNEVQQQQKVIDDKQQESVEQSLHEQSA 1519 Query: 570 KVAELEEEKGN-LQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQ 628 + E +EE + L+D + + I+ + ++ IE + +E + + LE Q+ V Sbjct: 1520 QQREQKEEFSEPSKQQLIDQQASQKIQGEEKQQKIEENDKSELVIDTSNQLEIQEEKQVT 1579 Query: 629 EL--------HILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELAL 680 + HIL Q +E++ ++ DIS + D + S +L + + + E L Sbjct: 1580 SIIKHDEDCKHILLQS-EEIQ-QVVDISN-EKDDPTHQTFSNNLN---NIVIEQQNEQIL 1633 Query: 681 VIENLKLDKEQLYGTI-KDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKI 739 ++ +Q + I + D E I+ N + + +K + MS ++ Sbjct: 1634 NSNQIEAKSDQNHQQIDSKFQADGEQILLSNSN---NQIKIQEKSDDMSQIEVEN--ENN 1688 Query: 740 NHEEQS----KIQTQFG--IDAKIQER-DLYIENIESELSKYKSRICRLEESIAVMEDRR 792 NHE+Q +I+TQ D Q++ D ++ + + S+Y + ++ ++ Sbjct: 1689 NHEDQQEDAMEIETQIDEQPDHLNQDQFDQILDQNQQKESQYNNDDKIKQQDSPKTKETE 1748 Query: 793 YSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQ 852 + + D L Y+ +KQ TIQ++ D+ ++ + L + E + KE Sbjct: 1749 WQIPNNLDIL-DYINQKQ------TIQKES---------DYQKISDVDLKK-EFDEKEYS 1791 Query: 853 KKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITH 912 + ++++ + + +M+Q+ + D E +S K + +L D +N+ + Sbjct: 1792 AE---FIKKSSPNSLEILEMKQNIS--------NDKKEEQSYKSEIKLGDANTNIGSVML 1840 Query: 913 EHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIE 972 + + + K+K + DL + +S + + ++ NE N++ V ++L + Sbjct: 1841 DMEKFL--KQKGLSDL------KNQSTVPNSEIKNE----NVDIVLSTNSKLTQ------ 1882 Query: 973 NLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKI 1032 V++ +K N + +Q + QS EQ NE L +L K++ +I+ +N + Sbjct: 1883 -----VQQEDKQN-----QCLQLRSDQSLFQKEQDHNERKNL-SLEKKQIFDIVNINNNV 1931 Query: 1033 NNAQVSYMSMVSDYESKLAQFTTKLENME-EEMQRVSKQLLDSKQHNEELQILVREQDDQ 1091 + ++ S + E E E+++ K + + RE D Sbjct: 1932 LSQMDQFLIQKSSQKDNFLNGDNIQEKQEIEQIESADKNYSFGNNSENIFERIKRESD-- 1989 Query: 1092 IKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFI 1151 K+L+E+ F+++ + +I+++ P + A + + F+ Sbjct: 1990 -KKLQES--GFQISSDQRNSLIVTNIFTPSNAKAISDCGGAQTQFSNESFGITPKRINFL 2046 Query: 1152 QERSVLQEQSAKLNT--ELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTE 1209 Q + ++ ++NT + Q+ Y +++ + + + Q N S QLN+ Sbjct: 2047 QSNKKSEAEATQINTDSQFQQLYQSKLKIADDQKLVEPKEELTQNTSNSNIS--SQLNSS 2104 Query: 1210 NDN 1212 N+N Sbjct: 2105 NEN 2107 >UniRef50_A0CVZ5 Cluster: Chromosome undetermined scaffold_3, whole genome shotgun sequence; n=4; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_3, whole genome shotgun sequence - Paramecium tetraurelia Length = 933 Score = 124 bits (299), Expect = 2e-26 Identities = 144/676 (21%), Positives = 313/676 (46%), Gaps = 68/676 (10%) Query: 468 VGTNTEDVNEIAKVQEQLK----------QELNDEI--KDVNVKDLIEKLKSAEEQITQL 515 + T ED N++ + EQL+ Q+LN + ++ V + I+K AEE+ Q Sbjct: 263 ISTMAEDYNKLKTILEQLQTKMTALVQENQKLNKNLIEQEQKVTEEIKKKLLAEEKANQA 322 Query: 516 NDEIDAANKNM-IKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAEL 574 N E + + + I K N +LK K + + D+F +S V++ +E+++ K +L Sbjct: 323 NKEFNRVFECLQINQKENEELKNKLISQ--DSFKNLSIQTSNRVQM-DEINNYKMKNQQL 379 Query: 575 EEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQ 634 + E L++ + + + ++ K ++++ + K LE + L E L+ Sbjct: 380 QNELEQLEMKYKQLLTEKNNQKEIPKSPSILKSIHSSSTKQSEQLELKLLQLQIENDNLK 439 Query: 635 QK--YDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQL 692 + +++V+ K+ D ++ +IKS+ E+ I S+++ + NL++ EQL Sbjct: 440 AEMAHNQVDSKVIDSKNDMIQKLEDKIKSILKEKSI-----SEEQSIQICHNLEIMNEQL 494 Query: 693 YGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFG 752 +++ E++ ++ + +++ + + L +M K +E ++ ++ K+ +F Sbjct: 495 KNGLQNKESEVSSLLKQKNESERDHRNQINYLNQML--KGTEDKVQVAKQDYQKLLDEFK 552 Query: 753 -IDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQK 811 ID + + + N E +L + + + + DR + + + DQ+ LQ++ + Sbjct: 553 QIDLRKSKLQEDLRNSEKKLDQLNQELAFTKGELKKSSDRNHQFQAQHDQMNQQLQQQSQ 612 Query: 812 AYSEYTIQEDELV-NRLAVLMDHDRVVEKQLLEIEHENK-ELQKKNQILLEENQNLQISL 869 + Q D L + + M+++++ EKQ+ ++ E K ++ + N+++ + + Q Sbjct: 613 LQQQLLQQIDGLKQSEQQIRMEYEKL-EKQMQAVKSEMKYQVTELNEMISLQARKTQ--- 668 Query: 870 SDMQQHYNALVEK-ANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDL 928 + ++ N L+E+ D E + Q + DLE LK + + L+ K++EI DL Sbjct: 669 -EKERQLNELIEEMGGMRDQYEVQKKVCQENVNDLERRLKNQRLQQEELLQVKEQEILDL 727 Query: 929 EIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLEL 988 + + QI+ + + + Y++ + QL+A+L + IE L VE++ N + Sbjct: 728 KQTMDQQIKMLDKRNALSSFDYDQREQ---QLQAELLSKNDQIEGLKSEVEKVRSNNFNI 784 Query: 989 IDKHVQK--QQTQSPDYTEQYINEINK-------LNALLKQKDEEIIALNQKINN----- 1034 ++ +++ Q Q Y NE+ + L+ +LK++ EE L+Q + Sbjct: 785 QEELLRQGMQLNQHQATIANYKNELTQSRQEQQHLSEMLKKRKEETEQLHQNLEEMRREL 844 Query: 1035 -----AQVSYMSMVSDYESKLA---------QFTTKLENMEEEMQRVSKQLLDSKQHNEE 1080 + S S++ + ++A K+ + EM R S++L + NEE Sbjct: 845 QSKKMSDDSRRSVLRQQDLQIALENLSRENLSLQQKINGLSNEMNRKSREL---SERNEE 901 Query: 1081 LQILVREQDDQIKELK 1096 QIL R+ D+ + L+ Sbjct: 902 YQILKRKYDETVANLE 917 Score = 79.4 bits (187), Expect = 8e-13 Identities = 147/739 (19%), Positives = 322/739 (43%), Gaps = 62/739 (8%) Query: 617 SLLESQKFDLVQELHILQQKYDEVEDKLADI-SQLQSDQVCSEIKSVHLEEQIDALSASK 675 S L SQ +L+Q +Q + + L D+ S +Q ++ ++ I+ L+ + Sbjct: 184 SRLSSQNINLMQSKPKIQTEIYRISGALRDLMSSIQKMMGDGKLPDQINDKMIEILANFR 243 Query: 676 K--ELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQN----YIQENMDLTDKLEKMSA 729 K E+A D + T+ + N + I+ +LQ +QEN L L + Sbjct: 244 KLEEIANSEPMPASDNDSKISTMAEDYNKLKTILEQLQTKMTALVQENQKLNKNLIEQEQ 303 Query: 730 EKISELLAKINHEEQ-SKIQTQFG-IDAKIQERDLYIENIESEL-SKYKSRICRLEESIA 786 + E+ K+ EE+ ++ +F + +Q E ++++L S+ + ++ S Sbjct: 304 KVTEEIKKKLLAEEKANQANKEFNRVFECLQINQKENEELKNKLISQDSFKNLSIQTSNR 363 Query: 787 VMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQED---ELVNRLAVLMDHDRVVEKQLLE 843 V D + + K QL + L++ + Y + +++ E+ ++L KQ + Sbjct: 364 VQMDEINNYKMKNQQLQNELEQLEMKYKQLLTEKNNQKEIPKSPSILKSIHSSSTKQSEQ 423 Query: 844 IEHENKELQKKNQILLEENQNLQI------SLSDMQQHYNALVEK-ANRTDLAESESTKY 896 +E + +LQ +N L E + Q+ S +DM Q ++ ++E +S + Sbjct: 424 LELKLLQLQIENDNLKAEMAHNQVDSKVIDSKNDMIQKLEDKIKSILKEKSISEEQSIQI 483 Query: 897 QTQL----RDLESNLKRITHEHQTLIVQKKKEIED--LEIEFNTQIESAIRDK-KVLNEK 949 L L++ L+ E +L+ QK + D +I + Q+ DK +V + Sbjct: 484 CHNLEIMNEQLKNGLQNKESEVSSLLKQKNESERDHRNQINYLNQMLKGTEDKVQVAKQD 543 Query: 950 YEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYIN 1009 Y+K ++ Q++ + + + ++ N + ++L+++N EL + + +S D Q+ Sbjct: 544 YQKLLDEFKQIDLRKSKLQEDLRN---SEKKLDQLNQEL--AFTKGELKKSSDRNHQFQA 598 Query: 1010 EINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSK 1069 + +++N L+Q+ + L Q+I+ + S + +Y E +E++MQ V Sbjct: 599 QHDQMNQQLQQQSQLQQQLLQQIDGLKQSEQQIRMEY-----------EKLEKQMQAVKS 647 Query: 1070 QL-LDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNV 1128 ++ + NE + + R+ ++ ++L E L EM + + + + ++ N++ Sbjct: 648 EMKYQVTELNEMISLQARKTQEKERQLNE--LIEEMGGMRDQYEVQKKVCQ---ENVNDL 702 Query: 1129 DXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGH 1188 + L +E+E + + + +Q L+ + + +L Sbjct: 703 ERRLKNQRLQQEELLQVKEQEILDLKQTMDQQIKMLD---KRNALSSFDYDQREQQLQAE 759 Query: 1189 DVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREA 1248 + +QI LKS++E++ + N N+ + LR + ++Q IA +K L Q Sbjct: 760 LLSKNDQIEGLKSEVEKVRSNNFNIQEEL--LRQGMQ--LNQHQATIAN-YKNELTQSR- 813 Query: 1249 DFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRN 1308 Q+ +H L L + + EQL +++ +E +K ++ + S+ + QD + L N Sbjct: 814 --QEQQH-LSEMLKKRKEETEQLHQNLEEMRRELQSKKMSDDSRRSVLRQ-QDLQIALEN 869 Query: 1309 LQEKYADVINQIEILRSEI 1327 L + + +I L +E+ Sbjct: 870 LSRENLSLQQKINGLSNEM 888 Score = 78.6 bits (185), Expect = 1e-12 Identities = 139/690 (20%), Positives = 295/690 (42%), Gaps = 70/690 (10%) Query: 212 EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271 E + +MT + + + +++Q++ ++I+ K + +ANK FE + Sbjct: 278 EQLQTKMTALVQENQKLNKNLIEQEQKVTEEIKKKLLAEEKANQANKEFNRV-FECLQIN 336 Query: 272 SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELL 331 K +EL+ SI+ S + +++E + ++ N +L ++E L Sbjct: 337 QKENEELKNKLISQDS-------FKNLSIQTS--NRVQMDEINNYKMKNQ-QLQNELEQL 386 Query: 332 EHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSS 391 E Q+ T K + ++ + K++ S S K S + K +++ L + Sbjct: 387 EMKYKQLL-TEKNNQKEIPKSPSILKSIHSSSTKQSEQLELK-----LLQLQIENDNLKA 440 Query: 392 ETLNQDTDKKI--NKNE-IAKLEMVIQSLNKDL-VDKEYVISEKDTXXXXXXXXXXG--- 444 E + D K+ +KN+ I KLE I+S+ K+ + +E I G Sbjct: 441 EMAHNQVDSKVIDSKNDMIQKLEDKIKSILKEKSISEEQSIQICHNLEIMNEQLKNGLQN 500 Query: 445 KDTLIAQL--QLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKD-- 500 K++ ++ L Q + + ++ + + +V +Q Q+L DE K ++++ Sbjct: 501 KESEVSSLLKQKNESERDHRNQINYLNQMLKGTEDKVQVAKQDYQKLLDEFKQIDLRKSK 560 Query: 501 LIEKLKSAEEQITQLNDEIDAANKNMIKVKS--NHKLKLKQMQKTIDNFSKVSDSNKEIV 558 L E L+++E+++ QLN E+ A K +K S NH+ + + Q + S ++++ Sbjct: 561 LQEDLRNSEKKLDQLNQEL-AFTKGELKKSSDRNHQFQAQHDQMN-QQLQQQSQLQQQLL 618 Query: 559 RLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISL 618 + + L Q++ +E EK Q+ V +S++ ++ E+ + + + Sbjct: 619 QQIDGLKQSEQQI-RMEYEKLEKQMQAV--------KSEMKYQVTELNEMISLQARKTQE 669 Query: 619 LESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKEL 678 E Q +L++E+ ++ +Y EV+ K VC E + LE ++ ++EL Sbjct: 670 KERQLNELIEEMGGMRDQY-EVQKK-----------VCQENVN-DLERRLKNQRLQQEEL 716 Query: 679 ALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKIS--ELL 736 V E LD +Q D + D N L ++ D + +++ AE +S + + Sbjct: 717 LQVKEQEILDLKQTM----DQQIKMLDKRNALSSF-----DYDQREQQLQAELLSKNDQI 767 Query: 737 AKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLE 796 + E + F I ++ + + + ++ ++ YK+ + + + + + + Sbjct: 768 EGLKSEVEKVRSNNFNIQEELLRQGMQLNQHQATIANYKNELTQSRQEQQHLSEMLKKRK 827 Query: 797 RKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQ 856 + +QL L+E ++ + +D +R +VL D ++ L + EN LQ+K Sbjct: 828 EETEQLHQNLEEMRRELQSKKMSDD---SRRSVLRQQD--LQIALENLSRENLSLQQKIN 882 Query: 857 ILLEENQNLQISLSDMQQHYNALVEKANRT 886 L E LS+ + Y L K + T Sbjct: 883 GLSNEMNRKSRELSERNEEYQILKRKYDET 912 Score = 72.1 bits (169), Expect = 1e-10 Identities = 110/587 (18%), Positives = 226/587 (38%), Gaps = 34/587 (5%) Query: 1010 EINKLNALLKQKDEEIIAL---NQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQR 1066 + NKL +L+Q ++ AL NQK+N + V++ K K +E R Sbjct: 269 DYNKLKTILEQLQTKMTALVQENQKLNKNLIEQEQKVTEEIKKKLLAEEKANQANKEFNR 328 Query: 1067 VSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDAN 1126 V + L +++ NEEL+ + QD K + + E + + ++ Sbjct: 329 VFECLQINQKENEELKNKLISQDS----FKNLSIQTSNRVQMDEINNYKMKNQQLQNELE 384 Query: 1127 NVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELT 1186 ++ + ++E + S+L+ + + ++ K++QL+ N L Sbjct: 385 QLEMKYKQLLT-----EKNNQKEIPKSPSILKSIHSSSTKQSEQLELKLLQLQIENDNLK 439 Query: 1187 GHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVD-QRGFEIA-ELWKQHLA 1244 NQ + SK + + D + S + E S ++ EI E K L Sbjct: 440 AEMAHNQVDSKVIDSKNDMIQKLEDKIKSILKEKSISEEQSIQICHNLEIMNEQLKNGLQ 499 Query: 1245 QREADF-----QKTEHEL--RVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQN 1297 +E++ QK E E R Q++ + D VQ + Q+ + +Q+ ++ Sbjct: 500 NKESEVSSLLKQKNESERDHRNQINYLNQMLKGTEDKVQVAKQDYQKLLDEFKQIDLRKS 559 Query: 1298 KLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQ 1357 KLQ E LRN ++K + ++ + E++ + + Q Sbjct: 560 KLQ---EDLRNSEKKLDQLNQELAFTKGELKKSSDRNHQFQAQHDQMNQQLQQQSQLQQQ 616 Query: 1358 SYKQMQ--EQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSE 1415 +Q+ +QS I E +L+K +N+ + T + E + +E Sbjct: 617 LLQQIDGLKQSEQQIRMEYEKLEKQMQAVKSEMKYQVTELNEMISLQARKTQEKERQLNE 676 Query: 1416 IYQK----THEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENAN 1471 + ++ +Y + + ++ ++L + E+L KE E+ L+ M + Sbjct: 677 LIEEMGGMRDQYEVQKKVCQENVNDLERRLKNQRLQQEELLQVKEQEILDLKQTMDQQIK 736 Query: 1472 HYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEI 1531 + S + + ++L E +S N Q+ L +E+ + +Q L Q + Sbjct: 737 MLDKRNALSSFDYDQREQQLQ---AELLSKNDQIEGLKSEVEKVRSNNFNIQEELLRQGM 793 Query: 1532 EIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNK 1578 ++ I N +N + S + Q+H+S ++ EQL + + Sbjct: 794 QLNQHQATIANYKNELTQSRQE-QQHLSEMLKKRKEETEQLHQNLEE 839 Score = 68.5 bits (160), Expect = 1e-09 Identities = 131/689 (19%), Positives = 277/689 (40%), Gaps = 60/689 (8%) Query: 849 KELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLK 908 ++LQ K L++ENQ L +L + +Q + E+ + LAE ++ + + + L+ Sbjct: 278 EQLQTKMTALVQENQKLNKNLIEQEQ---KVTEEIKKKLLAEEKANQANKEFNRVFECLQ 334 Query: 909 RITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYK 968 E++ L + K +D + Q + ++ ++ N K KN Q+ + Sbjct: 335 INQKENEEL--KNKLISQDSFKNLSIQTSNRVQMDEINNYKM-KN-----------QQLQ 380 Query: 969 NNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIAL 1028 N +E L M ++L L +K+ QK+ +SP + + K + L E+ L Sbjct: 381 NELEQLEMKYKQL------LTEKNNQKEIPKSPSILKSIHSSSTKQSEQL-----ELKLL 429 Query: 1029 NQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQ 1088 +I N + + +SK+ +M ++++ K +L K +EE I + Sbjct: 430 QLQIENDNLKAEMAHNQVDSKVID---SKNDMIQKLEDKIKSILKEKSISEEQSIQICHN 486 Query: 1089 DDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKV--QE 1146 + + E + L N ++ E D N ++ ++V Q+ Sbjct: 487 LEIMNEQLKNGL---QNKESEVSSLLKQKNESERDHRNQINYLNQMLKGTEDKVQVAKQD 543 Query: 1147 EEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQL 1206 ++ + E + + +KL +L+ K+ QL G + ++ +Q +++ +Q+ Sbjct: 544 YQKLLDEFKQIDLRKSKLQEDLRNSEKKLDQLNQELAFTKGELKKSSDRNHQFQAQHDQM 603 Query: 1207 N---TENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLA-QREADFQKTEHELRVQLS 1262 N + L + + + + Q E +L KQ A + E +Q TE + L Sbjct: 604 NQQLQQQSQLQQQLLQQIDGLKQSEQQIRMEYEKLEKQMQAVKSEMKYQVTELNEMISLQ 663 Query: 1263 A--FESKYEQLLDSVQS----STQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADV 1316 A + K QL + ++ Q E K V E V L+ +L+++ R QE+ V Sbjct: 664 ARKTQEKERQLNELIEEMGGMRDQYEVQKKVCQENVNDLERRLKNQ----RLQQEELLQV 719 Query: 1317 INQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTEN-QSYKQMQEQSILNINEENA 1375 Q + + D+++ D R + Q+ + I + E Sbjct: 720 KEQEILDLKQTMDQQIKM----LDKRNALSSFDYDQREQQLQAELLSKNDQIEGLKSEVE 775 Query: 1376 QLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFE 1435 +++ ++ ++N +A + ++L ++ Q+ + L +R +E E Sbjct: 776 KVRSNNFNIQEELLRQGMQLNQHQATIANYKNEL----TQSRQEQQHLSEMLKKRKEETE 831 Query: 1436 NVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVK-LIEELNVK 1494 + Q L E + ++ +S ++LR + + A + + S +++ L E+N K Sbjct: 832 QLHQNLEEMRRELQSKKMSDDSRRSVLRQQDLQIALENLSRENLSLQQKINGLSNEMNRK 891 Query: 1495 ITESVSLNKQVAELNKALEEEVAKTNEMQ 1523 E N++ L + +E VA ++ Sbjct: 892 SRELSERNEEYQILKRKYDETVANLERLE 920 >UniRef50_P75471 Cluster: Cytadherence high molecular weight protein 2; n=6; Mycoplasma|Rep: Cytadherence high molecular weight protein 2 - Mycoplasma pneumoniae Length = 1818 Score = 124 bits (299), Expect = 2e-26 Identities = 230/1148 (20%), Positives = 490/1148 (42%), Gaps = 106/1148 (9%) Query: 498 VKDLIEKLKSAEEQITQLNDE----IDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDS 553 V +L K + ++++ +L E +++ N +SN++LKL Q Q ID ++ Sbjct: 106 VAELNNKARFFKDELKRLQQENAAFVNSRYANWADFQSNYQLKLDQFQALIDQQNQTIKQ 165 Query: 554 NKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRL 613 E + + L + Q V L++ N L + D+ +Y ++ E+EN + RL Sbjct: 166 LNEQIAANQGL--IDQNVQRLQQ---NHSLDQQERDALLYEVDHLYNELYELEN--QKRL 218 Query: 614 KAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSA 673 I E+ DLV LQ Y+ + A+ Q Q D +++K V E+QI Sbjct: 219 VGIE-YEATYQDLVSADAELQNVYETIAQNQANF-QKQCDAYWAQLKQV--EQQI---QT 271 Query: 674 SKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKL--QNYI--QENMDLTDKLEKMSA 729 +K+EL LK+ I + +D+ +K+ ++++ ++ D+ L ++ Sbjct: 272 TKQELVDEESTLKVRLNDADFYINSRLAELDDLTSKINERDFVSKEQAQDVKASLANLTK 331 Query: 730 EKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVME 789 EK L A+ + E+ + I+ QE L+ +++E + +++ + +ES+ +E Sbjct: 332 EK-ERLSAEKDSFERLRNTALNDINRMEQENALFAKHLEQQQYEFER---KQQESLLKLE 387 Query: 790 DRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHE-- 847 L+++ +G + E + IQE EL+ + + D ++ + LE E + Sbjct: 388 TEHKQLQKR---IGEFKIESEAKSEALLIQERELLEKRREI---DDLLTQASLEYEQQRR 441 Query: 848 -NKELQKKNQILLEENQNLQISLS--DMQQHYNALVEKANRTDLAESESTKYQTQLRDLE 904 N+ L++K++ + + QNL + D ++HY A ++ + + + + K T+ R+LE Sbjct: 442 TNQVLKEKHRQVQQHFQNLVHAKKKLDQKRHYLAEQKRIDEEQIFKLKE-KIATERRELE 500 Query: 905 -----SNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQ 959 K+ E+ LI + K++ + +F +IE + + +K+ + Sbjct: 501 KLYLVKKQKQDQKENDLLIFE--KQLRQYQADFENEIEEKQNELFASQKSLQKSFTQLKN 558 Query: 960 LEAQLQEYKNNIEN--LNMNVEELNKMNLELI----DKHVQKQQTQSPDYTEQYINEINK 1013 EA+L + I ++ + + +LE+ H+Q+++ + + Q+ N ++ Sbjct: 559 KEAELNQKAQKIAEDWAHLKQNKHHHADLEIFLEGEFNHLQQEKHKLLEARTQFDNRVSL 618 Query: 1014 LNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLD 1073 L+A KQK E++ Q + ++ + E+ + +L N+E++ K++L Sbjct: 619 LSARFKQKQAELVKQKQSLEQLTAAFN---KEQEAVERDWKDRLANLEKQ-----KEMLG 670 Query: 1074 SKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXX 1133 K H + L + K+L E +L + + E +++ ++ + Sbjct: 671 DKVHQFDENSL-----NISKKLAERELAIKFKEKELEAAQKQLSLDNNNNAGLKLQLDKL 725 Query: 1134 XXXXXXXXLKVQEEEEFIQE-RSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHD--- 1189 L+++ +E I + + A ++LQ ++ LE E Sbjct: 726 SESLKTERLELEASKERILDFYDESSRRIADYESDLQARLAEVKTLEKNQQETAAKSERE 785 Query: 1190 -VVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREA 1248 V E++NQ K Q+ + L +A ++ ++ + + AEL KQ + EA Sbjct: 786 LKVALEKLNQAKKAFLQIRKQQ---LLEIASVKQQLAQKANLLKNQQAELDKQ-TEELEA 841 Query: 1249 DF--QKTE-HELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEH 1305 F Q T+ EL L + +SK ++LL+ +S ++ + E V + ++ K Sbjct: 842 AFLEQDTDKKELEKALHSVKSK-QELLERERSFLLQKQREFA--EHVAGFKRQVHFKTTQ 898 Query: 1306 LRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQ 1365 ++ L E + Q E ++ E E K+AF + + Q +K+++ Sbjct: 899 MQRLSE--FNKQQQSEQIKRETE-LKIAFADLKKDYQLFELQKNQEFQQIEQKHKELE-- 953 Query: 1366 SILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTI 1425 + ++ A+LK+ A+ + H+LEL+ + Q ++ Sbjct: 954 ---LLAQKQAELKQELEQKATALASQDQDTVQAKLDLARQQHELELRQNAFNQA----SL 1006 Query: 1426 TLTQRNDEFEN-VRQQLVEYEKRIEDLTY------EKESELAILRLKMHENANHYETMQK 1478 +L ++ ++ N V+ E +KR E LT EKE + ++++ +E Sbjct: 1007 SLNKQREQLTNQVKVLHGELKKRHEKLTLKDRLLAEKEKDQHKKDAEINQRFKQFENEYA 1066 Query: 1479 ESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVT-LN 1537 + + + + ++ELN N + + L + A ++Q + +++ T + Sbjct: 1067 DFDQAKKRELQELNQIRRNLEQSNASLLKKRNQLTLDFALLRKVQHNTQTNRVQLNTQIK 1126 Query: 1538 DEITNLQNMVRAS-SSKIQKHV------SFASDTKQGRDEQLDNTMNKELLDAVPRAELD 1590 + + +N +AS + +QK + SFAS + R+ + + D ++E++ Sbjct: 1127 EFLLEKKNFQKASDEAALQKALLIKRLRSFASKLQLQREALAIQKLEFDKRDEQQKSEIN 1186 Query: 1591 LAMYMLHQ 1598 A L Q Sbjct: 1187 NAKLQLEQ 1194 Score = 110 bits (265), Expect = 3e-22 Identities = 269/1546 (17%), Positives = 621/1546 (40%), Gaps = 142/1546 (9%) Query: 90 ISESLANTLKQKEILMEKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXX---XQLGDVTH 146 I+++ AN KQ + ++KQ ++ + + +V +L ++ Sbjct: 244 IAQNQANFQKQCDAYWAQLKQVEQQIQTTKQELVDEESTLKVRLNDADFYINSRLAELDD 303 Query: 147 LSNTIKEKDNALSVLQVKMKIMETTILDLQEKIN-EKDQIIEAKNKATTXXXXXXXXXXX 205 L++ I E+D +K + +E+++ EKD +N A Sbjct: 304 LTSKINERDFVSKEQAQDVKASLANLTKEKERLSAEKDSFERLRNTALNDINRMEQENAL 363 Query: 206 XXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLK-DIESKDVRISSLEEANKLLEAAR 264 + + K QE+ + +E E K ++R+ + IES+ + L + +LLE R Sbjct: 364 FAKHLEQQQYEFERKQQESLLKLETEHKQLQKRIGEFKIESEAKSEALLIQERELLEKRR 423 Query: 265 -FEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSI---EPSCEEKTE-IEEKGSLEIA 319 + L + L E ++ Q++ + ++K + E+ ++ Sbjct: 424 EIDDLLTQASLEYEQQRRTNQVLKEKHRQVQQHFQNLVHAKKKLDQKRHYLAEQKRIDEE 483 Query: 320 NMTELTKKIEL----LEHLNCQIRQTNKELENKLATMGTESKAVSSP------SKKGSPL 369 + +L +KI LE L +Q + EN L + + + K+ Sbjct: 484 QIFKLKEKIATERRELEKLYLVKKQKQDQKENDLLIFEKQLRQYQADFENEIEEKQNELF 543 Query: 370 ISRKSGRNTASKMKSPWSQLS--SETLNQD-TDKKINKNEIAKLEMVIQSLNKDLVDKEY 426 S+KS + + +++K+ ++L+ ++ + +D K NK+ A LE+ ++ L +++ Sbjct: 544 ASQKSLQKSFTQLKNKEAELNQKAQKIAEDWAHLKQNKHHHADLEIFLEGEFNHLQQEKH 603 Query: 427 VISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDV-------NEIA 479 + E T + Q Q E + + + N E + +A Sbjct: 604 KLLEARTQFDNRVSLLSAR---FKQKQAELVKQKQSLEQLTAAFNKEQEAVERDWKDRLA 660 Query: 480 KVQEQLKQELNDEIK--DVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNH---K 534 +++Q K+ L D++ D N ++ +KL E I E++AA K + +N+ K Sbjct: 661 NLEKQ-KEMLGDKVHQFDENSLNISKKLAERELAIKFKEKELEAAQKQLSLDNNNNAGLK 719 Query: 535 LKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMI 594 L+L ++ +++ +++KE R+ + S+++A+ E + LQ L + + Sbjct: 720 LQLDKLSESLKTERLELEASKE--RILDFYDESSRRIADYESD---LQARLAEVKTLEKN 774 Query: 595 ESDVYKKM-----IEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQ 649 + + K + +E L + + + + + Q ++ L QK + ++++ A++ Sbjct: 775 QQETAAKSERELKVALEKLNQAKKAFLQIRKQQLLEIASVKQQLAQKANLLKNQQAEL-- 832 Query: 650 LQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNK 709 D+ E+++ LE+ D KKEL + ++K K++L LE ++ ++ K Sbjct: 833 ---DKQTEELEAAFLEQDTD-----KKELEKALHSVK-SKQEL------LERERSFLLQK 877 Query: 710 LQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIES 769 + + + ++ + + + L++ N ++QS+ Q + + KI DL + Sbjct: 878 QREFAEHVAGFKRQVHFKTTQM--QRLSEFNKQQQSE-QIKRETELKIAFADLKKDYQLF 934 Query: 770 ELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAV 829 EL K + +E + LE A + QE ++ + Q+ + V Sbjct: 935 ELQK--------NQEFQQIEQKHKELELLAQKQAELKQELEQKATALASQDQDTVQAKLD 986 Query: 830 LMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLA 889 L +E + + L K+ + L + +++ ++++ + L K LA Sbjct: 987 LARQQHELELRQNAFNQASLSLNKQREQLTNQ---VKVLHGELKKRHEKLTLKDRL--LA 1041 Query: 890 ESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEK 949 E E +++ ++ K+ +E+ KK+E+++L + +E + + +L ++ Sbjct: 1042 EKEKDQHKKDA-EINQRFKQFENEYADFDQAKKRELQELN-QIRRNLEQS--NASLLKKR 1097 Query: 950 YEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYIN 1009 + +++ + Q N ++ LN ++E L K+ QK ++ I Sbjct: 1098 NQLTLDFALLRKVQHNTQTNRVQ-LNTQIKEFL-----LEKKNFQKASDEAALQKALLIK 1151 Query: 1010 EINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSK 1069 + + L+ + E + + + S +++ + +L QF + +N +E Q K Sbjct: 1152 RLRSFASKLQLQREALAIQKLEFDKRDEQQKSEINNAKLQLEQFKLEKQNFDEAKQ---K 1208 Query: 1070 QLLDSKQHNEELQI---LVREQDDQIKELKETKLTFEMNIPKTEGMIIS--STIEPMSDD 1124 QL++ K + L + L++++ Q+K L ++ LT++ ++ + + + + + Sbjct: 1209 QLIEFKDQCQRLDVEKRLLKQKLVQLKNLSKSYLTYKNRADLSQQQLQHKYANLLELKEK 1268 Query: 1125 ANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTE 1184 Q E QE+ L +++ + + L+ L++E Sbjct: 1269 LQTAKRALDKKHRAIYGKMAQFVSELRQEKKQLLSAQKQVDDKSRLLEQNQRHLQNLSSE 1328 Query: 1185 LTGHDVVNQEQINQL----KSKLEQLNTENDNLLSTVAELR---SSISSAVDQRGFEIAE 1237 + IN+ K + + + L EL+ +S Q E ++ Sbjct: 1329 TKKKRQSLEHDINKFDQRRKEAVSSILNSHKKLKQKEGELQGILQKLSLKKTQIEQEFSK 1388 Query: 1238 LWKQH--LAQREADFQKTEHELRVQLSAFESKYEQLLD-------SVQSSTQE----ETN 1284 L++Q L ++ K EL+ Q A K ++L+ +Q T E + N Sbjct: 1389 LYQQREKLDRQRTTLSKLHRELKAQNEATAHKNREVLEIENYYKKELQRLTTEKSEFDNN 1448 Query: 1285 KIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXX 1344 K E ++N+++ KE H++ + E+ + +E ++ +K + Sbjct: 1449 KNRLFEYFRKIRNEIEKKEAHIKTVLEETQKKRHLVETEAVKLHLQKQSIISKGQELKEI 1508 Query: 1345 XXXXXXDLRTENQSYKQ----MQEQSIL--NINEENAQLKKSSXXXXXXXXXXXXRVNDA 1398 D+ N+ ++ + + +L N+ E ++ ++++ Sbjct: 1509 KERVSRDISHTNKQREELNSLLHQNKLLQKNLAEREREINNKDSLLTQKIQTAKQKLSEK 1568 Query: 1399 EAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVE--YEKRIEDLTYEKE 1456 EA++L+L ++ + + YQ E T T+ D +N + L ++ D+ Y Sbjct: 1569 EARILKLLEKMRAVEQQ-YQA--EITRLKTRNADLEKNDNKHLFPPLFKINGNDMNYPYP 1625 Query: 1457 SELAILRLKMHENANHYETM-QKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEE 1515 + K +++N + +++ + + + EL + L K++ ++ LE + Sbjct: 1626 YPWFYPQQKQEDSSNQIRHLFEQQLQFMQQRYENELTELRRQRALLEKKLDQIQ--LESQ 1683 Query: 1516 V-AKTNE-------MQTALENQEIEIVTLNDEITNLQNMVRASSSK 1553 + AK N+ MQ LE E ++ + +I L + ++ Sbjct: 1684 LSAKKNDFEKVEQMMQKLLEKTEQKLSAFDQKINALAEQINTQKAE 1729 Score = 103 bits (248), Expect = 3e-20 Identities = 207/1124 (18%), Positives = 465/1124 (41%), Gaps = 72/1124 (6%) Query: 498 VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEI 557 V L +L E Q + E +A ++++ + + + + + NF K D+ Sbjct: 202 VDHLYNELYELENQKRLVGIEYEATYQDLVSADAELQNVYETIAQNQANFQKQCDAYWAQ 261 Query: 558 VRLTEELHHLSQKVAELEEEKGNLQLHLVDYD---SGRMIE-SDVYKKMIEMENLAETRL 613 ++ E+ +++ EL +E+ L++ L D D + R+ E D+ K+ E + +++ + Sbjct: 262 LKQVEQQIQTTKQ--ELVDEESTLKVRLNDADFYINSRLAELDDLTSKINERDFVSKEQA 319 Query: 614 KAISLLESQKFDLVQELHILQQKYDEVEDK-LADISQLQSDQVCSEIKSVHLEEQIDALS 672 + + + + L + ++ + + L DI++++ + + + HLE+Q Sbjct: 320 QDVKASLANLTKEKERLSAEKDSFERLRNTALNDINRMEQENA---LFAKHLEQQQYEFE 376 Query: 673 ASKKELALVIENLKLDKEQLYGTIK-DLENDKEDIMNKLQNYIQENMDLTDKLEKMSAE- 730 ++E L +E ++ G K + E E ++ + + +++ ++ D L + S E Sbjct: 377 RKQQESLLKLETEHKQLQKRIGEFKIESEAKSEALLIQERELLEKRREIDDLLTQASLEY 436 Query: 731 ----KISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIA 786 + +++L + + + Q Q K+ ++ Y+ + + + +I +L+E IA Sbjct: 437 EQQRRTNQVLKEKHRQVQQHFQNLVHAKKKLDQKRHYLAE-QKRIDE--EQIFKLKEKIA 493 Query: 787 VME---DRRYSLER-KADQLGSYLQEKQKAYSEYTIQ-EDELVNRLAVLMDHDRVVEKQL 841 ++ Y +++ K DQ + L +K +Y E+E+ + L + ++K Sbjct: 494 TERRELEKLYLVKKQKQDQKENDLLIFEKQLRQYQADFENEIEEKQNELFASQKSLQKSF 553 Query: 842 LEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLR 901 +++++ EL +K Q + E+ +L+ + L + N + + + +TQ Sbjct: 554 TQLKNKEAELNQKAQKIAEDWAHLKQNKHHHADLEIFLEGEFNHLQQEKHKLLEARTQFD 613 Query: 902 DLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLE 961 + S L + Q +V++K+ +E L FN + E+ RD K EK E + Sbjct: 614 NRVSLLSARFKQKQAELVKQKQSLEQLTAAFNKEQEAVERDWKDRLANLEKQKEMLGDKV 673 Query: 962 AQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQK 1021 Q E NI E K + ++ QKQ + + +++KL+ LK + Sbjct: 674 HQFDENSLNISKKLAERELAIKFKEKELEA-AQKQLSLDNNNNAGLKLQLDKLSESLKTE 732 Query: 1022 DEEIIALNQKINNAQVSYMSMVSDYES----KLAQFTTKLENMEEEMQRVSKQL-LDSKQ 1076 E+ A ++I + ++DYES +LA+ T +N +E + ++L + ++ Sbjct: 733 RLELEASKERILDFYDESSRRIADYESDLQARLAEVKTLEKNQQETAAKSERELKVALEK 792 Query: 1077 HNEELQILVREQDDQIKELKETK--LTFEMNIPKTEGMIISSTIEPM-------SDDANN 1127 N+ + ++ + Q+ E+ K L + N+ K + + E + D Sbjct: 793 LNQAKKAFLQIRKQQLLEIASVKQQLAQKANLLKNQQAELDKQTEELEAAFLEQDTDKKE 852 Query: 1128 VDXXXXXXXXXXXXLK------VQEEEEFIQERSVLQEQSAKLNTELQEC--YTKIIQLE 1179 ++ L+ +Q++ EF + + + Q T++Q + K Q E Sbjct: 853 LEKALHSVKSKQELLERERSFLLQKQREFAEHVAGFKRQVHFKTTQMQRLSEFNKQQQSE 912 Query: 1180 TLNTE----LTGHDVVNQEQINQLKSKLE-QLNTENDNLLSTVAELRSSISSAVDQRGFE 1234 + E + D+ Q+ +L+ E Q + L +A+ ++ + ++Q+ Sbjct: 913 QIKRETELKIAFADLKKDYQLFELQKNQEFQQIEQKHKELELLAQKQAELKQELEQKATA 972 Query: 1235 IAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTME-QVT 1293 +A Q Q + D + +HEL ++ +AF Q S+ ++ TN++ + ++ Sbjct: 973 LAS-QDQDTVQAKLDLARQQHELELRQNAF----NQASLSLNKQREQLTNQVKVLHGELK 1027 Query: 1294 SLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLR 1353 KL K+ L ++ +I + E+E F +L Sbjct: 1028 KRHEKLTLKDRLLAEKEKDQHKKDAEINQRFKQFENEYADFDQAKKRELQELNQIRRNLE 1087 Query: 1354 TENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVND--AEAKVLE-LTHQLE 1410 N S + + Q L+ A L+K ++ + E K + + + Sbjct: 1088 QSNASLLKKRNQLTLDF----ALLRKVQHNTQTNRVQLNTQIKEFLLEKKNFQKASDEAA 1143 Query: 1411 LKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYE-KESELAILRLKMHEN 1469 L+ + + ++ + L + E + Q +E++KR E E ++L + + K+ E Sbjct: 1144 LQKALLIKRLRSFASKLQLQR---EALAIQKLEFDKRDEQQKSEINNAKLQLEQFKL-EK 1199 Query: 1470 ANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQ 1529 N E QK+ IE + L+V+ Q+ L+K+ + + Q L+++ Sbjct: 1200 QNFDEAKQKQL-IEFKDQCQRLDVEKRLLKQKLVQLKNLSKSYLTYKNRADLSQQQLQHK 1258 Query: 1530 EIEIVTLNDEITNLQNMVRASSSKIQ-KHVSFASDTKQGRDEQL 1572 ++ L +++ + + I K F S+ +Q + + L Sbjct: 1259 YANLLELKEKLQTAKRALDKKHRAIYGKMAQFVSELRQEKKQLL 1302 >UniRef50_A5DD85 Cluster: Putative uncharacterized protein; n=1; Pichia guilliermondii|Rep: Putative uncharacterized protein - Pichia guilliermondii (Yeast) (Candida guilliermondii) Length = 1375 Score = 124 bits (298), Expect = 3e-26 Identities = 232/1199 (19%), Positives = 485/1199 (40%), Gaps = 97/1199 (8%) Query: 471 NTEDVNEIAKVQEQLK----QELNDEIKDVNVKDLIEKLKSAEEQITQLND---EIDAAN 523 N ED+NE+ +VQ + + Q+L +++V + L K+ E ++Q D E++ Sbjct: 43 NKEDLNELLRVQTEQRAEHIQQLERYVEEV-LSSLTGKVNDLESSLSQKIDKIAELEEKL 101 Query: 524 KNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQL 583 K +V K ++ K ++ + L E + L +++ + +K L Sbjct: 102 KRTEEVLDAELHKGTELPKLSQTAELIAGEGISLSSLYVEFNQLKKQLVFEKSQKAKLAS 161 Query: 584 HLVDYDSGRMIESDVYKKMIEMENLAETRLK----AISLLESQKFDLVQELHILQQKYDE 639 L + + V E E+ LK + ++ +K + +E+ L+ + Sbjct: 162 QLESFVRELEEKKPVIASYQEQIQFYESSLKDMIGKVEVVRLEKAEADKEIRRLKSTLTD 221 Query: 640 VEDKLADISQLQSD---QVCSEIKSVHLEEQIDA-LS-ASKKELALVIENLKLDKEQLYG 694 E+ L +L D Q+C + + + + + LS A +K + ++E +KE Y Sbjct: 222 HENSLVSSKKLCRDLGTQLCYYLIHLRIRDNDEEPLSLAERKAIDNILERSG-NKEAKYE 280 Query: 695 TIKDLENDKE--------DIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSK 746 T D+ ++ K +N ++ +L KLE E +L + E + Sbjct: 281 TDTDMLISSRLVEFGSIVELQQKNENLLKVVRELGKKLEAKDQEHNEQLESAAIEEAKEA 340 Query: 747 IQTQFG--------IDAKIQERDLYIENIE-------SELSKYKSRIC-----RLEESIA 786 I T G ++A +ERD + IE S +Y + +C RL +S Sbjct: 341 IITLEGEIDSLHIKLNAVTKERD-QLRTIERTNPSGSSSEVRYLNEVCDDLRKRLSQSEK 399 Query: 787 VMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEH 846 + + + S ++ ++L + L E+ E I+ + V+ + + ++K L + Sbjct: 400 NLREAQESSAQRINELNTRLNEEATQRGELLIKVNTQVHAVEMAEVRYSNLQKLLKNCKE 459 Query: 847 ENKELQ-----------KKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTK 895 E K+L+ K+ +L+ + L + S++ ++ + D+A S Sbjct: 460 ELKQLKSDIAFWKEQASKQEALLIRKANELSDATSELSKNQAIINGLRTEKDMAISLQGS 519 Query: 896 YQTQ---LRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEK 952 + + LR +SNL Q+L+ +++ ++ N +E+ ++ L+E+ +K Sbjct: 520 LRDEVASLRSDKSNLSLFVSNLQSLLKEREASNAEISSRLNQAVENYQSLQERLSERDDK 579 Query: 953 NIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKH--VQKQQTQSPDYTEQYINE 1010 TQ E +L+ +E ++ ++L + L +K V+K ++Q+ ++ + N Sbjct: 580 ITMLTTQAELELKSQYIKLEQVSDLSQKLAEARSSLAEKTALVEKLRSQTSNHESSFQNA 639 Query: 1011 INKLNALLKQKDEEIIALNQ-KINNAQVS-YMSMVSDYESKLAQFTTKLENMEEEMQRVS 1068 + + D + ++ QV + S+ ++ E L T E + + + Sbjct: 640 LLQAQVASTNGDADESRFEALRLAEQQVQEFSSIANNAEKALMDATASFEQFKTDHEHKV 699 Query: 1069 KQLLDSK-QHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANN 1127 +L D + Q +E++ L E +E + + ++ + ++ S D Sbjct: 700 TELNDMRSQQQKEIERLSNEIQSANEERSKMTSQHMDEVQSLNSKLLEAIVKANSFDTMK 759 Query: 1128 VDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTG 1187 D L+ QE ER + +K + E +E + Q+ +LN EL+ Sbjct: 760 QDYETRLLSLRAD-LETQEARNADLERRLKDTADSKESLE-KEISSLRDQVNSLNEELSN 817 Query: 1188 HDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAEL------WKQ 1241 + ++ N+L + EQ NL + +LRS +SSA +Q + +L K Sbjct: 818 AKIALEDHNNELSNTAEQRAVALRNLQESFDDLRSKLSSAEEQNAILLNQLELNADNSKS 877 Query: 1242 HLAQRE-ADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQ 1300 Q + D LR + + E+K L + V + + + + +E S + Q Sbjct: 878 SPDQADNQDLSSVVRYLRHEKESAEAKVVTLTEQVNTLRLKLEHTNLELEARNSELLRSQ 937 Query: 1301 DKEEHLRNLQEKYADVINQIE---ILR---------SEIEDEKVAFXXXXXXXXXXXXXX 1348 L + +++ V+ Q+E ILR + I+ ++++ Sbjct: 938 KATIELDSTNQEHLKVLEQLEQLNILRESNTTLRNENRIQAKRLSELEQQLNDVSNSLAT 997 Query: 1349 XXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQ 1408 T++ ++Q I + EENA++K + V + + L ++ Sbjct: 998 IQVSLTQDAEKDDEKDQKIRLLEEENARIK--ANMSQTSTADNSEEVEALKKRFTNLKNE 1055 Query: 1409 LELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHE 1468 + K KT E + E ++ ++++E EK+ +K+ K+ Sbjct: 1056 FQNKLLVHRGKTKELEKVVENLRSELKS-NKKMLEDEKKSRQEVVDKQPNNEEGEQKLKA 1114 Query: 1469 NANHYETMQKESEIERVKLIEELNV---KITESVSLNKQVAELNKALEE---EVAKTNEM 1522 + E KE E+E+VKL +L V +VS++ +V ++ LE+ EV K+ Sbjct: 1115 LRDESEKRIKELELEKVKLEAQLQVLQKSGASNVSVSDEVEKVRGQLEKEKAEVEKSFSE 1174 Query: 1523 QTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFA-SDTKQGRDEQLDNTMNKEL 1580 + L ++IE + + +N++ ++ + K K + A KQ ++Q D + E+ Sbjct: 1175 KLKLAEEQIEALKRDSSNSNVEQLLAQEAEKQNKKLEEALQSRKQELEKQFDERLQTEI 1233 Score = 89.4 bits (212), Expect = 7e-16 Identities = 128/632 (20%), Positives = 285/632 (45%), Gaps = 46/632 (7%) Query: 503 EKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTE 562 E L+ AE+Q+ + + + A K ++ ++ + Q D+ KV++ N + + Sbjct: 658 EALRLAEQQVQEFSSIANNAEKALMDATASFE------QFKTDHEHKVTELNDMRSQQQK 711 Query: 563 ELHHLSQKVAELEEEKGNL-QLHLVDYDS--GRMIESDVYKKMIE-MENLAETRLKAISL 618 E+ LS ++ EE+ + H+ + S +++E+ V + M+ ETRL ++ Sbjct: 712 EIERLSNEIQSANEERSKMTSQHMDEVQSLNSKLLEAIVKANSFDTMKQDYETRLLSLRA 771 Query: 619 -LESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCS---EIKS--VHLEEQIDALS 672 LE+Q+ L+ D E +IS L+ DQV S E+ + + LE+ + LS Sbjct: 772 DLETQEARNADLERRLKDTADSKESLEKEISSLR-DQVNSLNEELSNAKIALEDHNNELS 830 Query: 673 ASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKI 732 + ++ A+ + NL+ + L + E ++N+L+ + D+ + + + Sbjct: 831 NTAEQRAVALRNLQESFDDLRSKLSSAEEQNAILLNQLELNADNSKSSPDQADN---QDL 887 Query: 733 SELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMED-- 790 S ++ + HE++S + ++ L +E+ EL S + R +++ ++ Sbjct: 888 SSVVRYLRHEKESAEAKVVTLTEQVNTLRLKLEHTNLELEARNSELLRSQKATIELDSTN 947 Query: 791 -RRYSLERKADQLGSYLQEKQKAYSEYTIQE---DELVNRLAVLMDHDRVVEKQLLEIEH 846 + + +QL + +E IQ EL +L + + ++ L + Sbjct: 948 QEHLKVLEQLEQLNILRESNTTLRNENRIQAKRLSELEQQLNDVSNSLATIQVSLTQDAE 1007 Query: 847 ENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESN 906 ++ E +K ++L EEN ++ ++S N+ +A + ++ ++Q +L Sbjct: 1008 KDDEKDQKIRLLEEENARIKANMSQTSTADNSEEVEALKKRFTNLKN-EFQNKLLVHRGK 1066 Query: 907 LKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVT-QLEAQLQ 965 K + + L + K + LE E ++ E + DK+ NE+ E+ ++ + + E +++ Sbjct: 1067 TKELEKVVENLRSELKSNKKMLEDEKKSRQE--VVDKQPNNEEGEQKLKALRDESEKRIK 1124 Query: 966 EYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINK-LNALLKQKDEE 1024 E + L ++ L K + + ++ + E+ E+ K + LK +E+ Sbjct: 1125 ELELEKVKLEAQLQVLQKSGASNVSVSDEVEKVRGQ--LEKEKAEVEKSFSEKLKLAEEQ 1182 Query: 1025 IIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLL----DSKQHN-- 1078 I AL + +N+ V + + + E + + L++ ++E+++ + L +S+Q N Sbjct: 1183 IEALKRDSSNSNVEQL-LAQEAEKQNKKLEEALQSRKQELEKQFDERLQTEIESRQQNIS 1241 Query: 1079 ---EELQILVREQDDQIKELK---ETKLTFEM 1104 + LV++ + QI+ELK E +LT E+ Sbjct: 1242 GGDSSSEELVKKYESQIEELKQDFEKRLTTEI 1273 Score = 84.6 bits (200), Expect = 2e-14 Identities = 168/909 (18%), Positives = 358/909 (39%), Gaps = 77/909 (8%) Query: 705 DIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYI 764 ++ +L++ + + L K E + +L K + E ++QT+ + IQ+ + Y+ Sbjct: 11 NLQAELESQTSKLLSLDSKFEVEKIKYAKDLKNKEDLNELLRVQTEQRAE-HIQQLERYV 69 Query: 765 ENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELV 824 E + S L+ + D SL +K D++ L+EK K E E Sbjct: 70 EEVLSSLT-------------GKVNDLESSLSQKIDKIAE-LEEKLKRTEEVLDAELHKG 115 Query: 825 NRLAVLMDHDRVVEKQLLEIEHENKEL-QKKNQILLEENQNLQISLSDMQQHYNALVEKA 883 L L ++ + + + E Q K Q++ E++Q +++ S ++ L EK Sbjct: 116 TELPKLSQTAELIAGEGISLSSLYVEFNQLKKQLVFEKSQKAKLA-SQLESFVRELEEK- 173 Query: 884 NRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKK---KEIEDLEIEFNTQIESAI 940 + YQ Q++ ES+LK + + + + ++K KEI L+ S + Sbjct: 174 ------KPVIASYQEQIQFYESSLKDMIGKVEVVRLEKAEADKEIRRLKSTLTDHENSLV 227 Query: 941 RDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQS 1000 KK+ + L QL Y ++ + + E L+ + ID +++ S Sbjct: 228 SSKKLCRD-----------LGTQLCYYLIHLRIRDNDEEPLSLAERKAIDNILER----S 272 Query: 1001 PDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENM 1060 + +Y + + L + + I+ L QK N + E+K + +LE+ Sbjct: 273 GNKEAKYETDTDMLISSRLVEFGSIVELQQKNENLLKVVRELGKKLEAKDQEHNEQLESA 332 Query: 1061 EEEMQRVSKQLLDSKQHNEELQI-LVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIE 1119 E + + L+ + + +++ V ++ DQ++ ++ T + + + + + Sbjct: 333 AIEEAKEAIITLEGEIDSLHIKLNAVTKERDQLRTIERTNPSGSSSEVRYLNEVCDDLRK 392 Query: 1120 PMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLE 1179 +S N+ L + EE Q +L K+NT++ ++ Sbjct: 393 RLSQSEKNLREAQESSAQRINELNTRLNEEATQRGELL----IKVNTQVHAVEMAEVRYS 448 Query: 1180 TLNTELTGHDVVNQEQINQLKSKL----EQLNTENDNLLSTVAELRSSISS-AVDQRGFE 1234 L L +E++ QLKS + EQ + + L+ EL + S + +Q Sbjct: 449 NLQKLLKNC----KEELKQLKSDIAFWKEQASKQEALLIRKANELSDATSELSKNQAIIN 504 Query: 1235 IAELWKQHLAQREADFQKTEHELRVQ---LSAFESKYEQLLDSVQSSTQEETNKI-VTME 1290 K + + LR LS F S + LL ++S E ++++ +E Sbjct: 505 GLRTEKDMAISLQGSLRDEVASLRSDKSNLSLFVSNLQSLLKEREASNAEISSRLNQAVE 564 Query: 1291 QVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXX 1350 SLQ +L ++++ + L + A++ + + ++ E + Sbjct: 565 NYQSLQERLSERDDKITMLTTQ-AELELKSQYIKLEQVSDLSQKLAEARSSLAEKTALVE 623 Query: 1351 DLRTENQSYKQMQEQSILN--INEENAQLKKSSXXXXXXXXXXXXR----VNDAEAKVLE 1404 LR++ +++ + ++L + N +S N+AE +++ Sbjct: 624 KLRSQTSNHESSFQNALLQAQVASTNGDADESRFEALRLAEQQVQEFSSIANNAEKALMD 683 Query: 1405 LTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRL 1464 T E ++ K E +Q+ E E + ++ + +T + E+ L Sbjct: 684 ATASFEQFKTDHEHKVTELNDMRSQQQKEIERLSNEIQSANEERSKMTSQHMDEVQSLNS 743 Query: 1465 KMHE---NANHYETMQKESEIERVKLIEELNVKITESVSLN---KQVAELNKALEEEVA- 1517 K+ E AN ++TM+++ E + L +L + + L K A+ ++LE+E++ Sbjct: 744 KLLEAIVKANSFDTMKQDYETRLLSLRADLETQEARNADLERRLKDTADSKESLEKEISS 803 Query: 1518 ---KTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDN 1574 + N + L N +I + N+E++N + +Q+ +EQ Sbjct: 804 LRDQVNSLNEELSNAKIALEDHNNELSNTAEQRAVALRNLQESFDDLRSKLSSAEEQNAI 863 Query: 1575 TMNKELLDA 1583 +N+ L+A Sbjct: 864 LLNQLELNA 872 Score = 84.6 bits (200), Expect = 2e-14 Identities = 167/868 (19%), Positives = 353/868 (40%), Gaps = 76/868 (8%) Query: 156 NALSVLQVKMKIMETTILDLQEKINE-KDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDT 214 +A+ + +V+ ++ + + +E++ + K I K +A+ E + Sbjct: 438 HAVEMAEVRYSNLQKLLKNCKEELKQLKSDIAFWKEQASKQEALLIRKANELSDATSELS 497 Query: 215 KQQ-----MTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISL 269 K Q + ++ I+++ +DE L D + + +S+L+ K EA+ EIS Sbjct: 498 KNQAIINGLRTEKDMAISLQGSLRDEVASLRSDKSNLSLFVSNLQSLLKEREASNAEIS- 556 Query: 270 EHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTE---IEEKGSL--EIANM-TE 323 S+L Q +E + + + E K++ +E+ L ++A + Sbjct: 557 --SRLNQAVENYQSLQERLSERDDKITMLTTQAELELKSQYIKLEQVSDLSQKLAEARSS 614 Query: 324 LTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPL-ISRKSGRNTASKM 382 L +K L+E L Q +N L S + + L ++ + + +S Sbjct: 615 LAEKTALVEKLRSQTSNHESSFQNALLQAQVASTNGDADESRFEALRLAEQQVQEFSSIA 674 Query: 383 KSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXX 442 + L T + + K +++++ +L + K++ I + Sbjct: 675 NNAEKALMDATASFEQFKTDHEHKVTELNDMRSQQQKEIERLSNEIQSANEERSKMTSQH 734 Query: 443 XGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIA--KVQEQLKQELNDEIKDV-NVK 499 + + LE + T ++ A + QE +L +KD + K Sbjct: 735 MDEVQSLNSKLLEAIVKANSFDTMKQDYETRLLSLRADLETQEARNADLERRLKDTADSK 794 Query: 500 DLIEK-LKSAEEQITQLNDEIDAA-------NKNMIKVKSNHKLKLKQMQKTIDNF-SKV 550 + +EK + S +Q+ LN+E+ A N + + L+ +Q++ D+ SK+ Sbjct: 795 ESLEKEISSLRDQVNSLNEELSNAKIALEDHNNELSNTAEQRAVALRNLQESFDDLRSKL 854 Query: 551 SDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYK--KMIEMENL 608 S + ++ L +L + ++ N L V ES K + E N Sbjct: 855 SSAEEQNAILLNQLELNADNSKSSPDQADNQDLSSVVRYLRHEKESAEAKVVTLTEQVNT 914 Query: 609 AETRLKAISL-LESQKFDLVQ------ELHILQQKYDEVEDKLADISQLQSDQVC----S 657 +L+ +L LE++ +L++ EL Q++ +V ++L ++ L+ + Sbjct: 915 LRLKLEHTNLELEARNSELLRSQKATIELDSTNQEHLKVLEQLEQLNILRESNTTLRNEN 974 Query: 658 EIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNY-IQE 716 I++ L E L+ LA + +L D E KD E D++ + + +N I+ Sbjct: 975 RIQAKRLSELEQQLNDVSNSLATIQVSLTQDAE------KDDEKDQKIRLLEEENARIKA 1028 Query: 717 NMDLTDKLEKMS-AEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYK 775 NM T + E + + + +E Q+K+ G K +E + +EN+ SEL K Sbjct: 1029 NMSQTSTADNSEEVEALKKRFTNLKNEFQNKLLVHRG---KTKELEKVVENLRSELKSNK 1085 Query: 776 SRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDR 835 + ++S + D++ + E +L + E +K E +++ +L +L VL Sbjct: 1086 KMLEDEKKSRQEVVDKQPNNEEGEQKLKALRDESEKRIKELELEKVKLEAQLQVLQKSGA 1145 Query: 836 V-------VEKQLLEIEHENKELQKK--NQILLEE-----------NQNLQISLSDMQQH 875 VEK ++E E E++K ++ L E N N++ L+ + Sbjct: 1146 SNVSVSDEVEKVRGQLEKEKAEVEKSFSEKLKLAEEQIEALKRDSSNSNVEQLLAQEAEK 1205 Query: 876 YNALVEKA---NRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEF 932 N +E+A + +L + + QT++ + N+ + L+ + + +IE+L+ +F Sbjct: 1206 QNKKLEEALQSRKQELEKQFDERLQTEIESRQQNISGGDSSSEELVKKYESQIEELKQDF 1265 Query: 933 NTQIESAIRD-KKVLNEKYEKNIEYVTQ 959 ++ + I D KK +K+E + + + Sbjct: 1266 EKRLTTEIEDIKKKTEKKFEIKVRMLNK 1293 >UniRef50_UPI000051A547 Cluster: PREDICTED: similar to CG6129-PB, isoform B; n=3; Endopterygota|Rep: PREDICTED: similar to CG6129-PB, isoform B - Apis mellifera Length = 2052 Score = 123 bits (297), Expect = 4e-26 Identities = 279/1312 (21%), Positives = 564/1312 (42%), Gaps = 134/1312 (10%) Query: 327 KIELLEHLNCQIR-QTNKE-LENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKS 384 K +L H Q++ QTNKE L+N + V + KK LI ++ Sbjct: 524 KYQLTIH-ELQVKLQTNKEQLQNTRKQCENAEENVKTLEKKAEELIIELDA------VRL 576 Query: 385 PWSQLSSET--LNQDTDK-KINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXX 441 SQL+ E L + D +I KN + K + + ++ ++L + + +K Sbjct: 577 HCSQLNQEKDMLQKGLDTIRIEKNTLEKTRIELNNMMENL-NNDCEKLQKANNKLQKICD 635 Query: 442 XXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQL---KQELNDEIKDVNV 498 + L Q +L + L + +E+ + +K++E+L ++ELN K Sbjct: 636 NLEDEKLYLQSELNRLS--KDVELRELNLRSEE-DRCSKMREELLTLREELN---KTYLS 689 Query: 499 KDLIEKLKSAEE----QITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDS- 553 KD++E+ K + QI + +++ + ++ KS+ + L +++ N + Sbjct: 690 KDMLEQQKLETDGLISQIEKSKGDLELELERVLLEKSDVQEVLMKLETVCSNHEQEKQRL 749 Query: 554 NKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRM-IESD------------VYK 600 +E+ ++TEE + L+ + + + + G+L+ L+ + R+ +ES+ + K Sbjct: 750 QEELKKVTEEKNKLANQCTDQQGDLGSLRKELLQAEQTRLDLESEKVTLNEKVKFLEIEK 809 Query: 601 KMIEMENLAETRLKA-----ISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQV 655 + IE+E TR + +S+L +K L +EL L+Q+ ++ + I++ D V Sbjct: 810 EKIEIELAQVTRERGDFNNQLSVLARKKETLNEELMRLKQRLEQANEMNGRINRNLEDLV 869 Query: 656 C-SEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYI 714 +E K V LE + +++LA +++ +KE L G + D + E++ K Sbjct: 870 KDNEEKQVLLETNEKEVQRLQEQLA----SMRSEKETLEGVLFDTQTSLENMHVKKTQLE 925 Query: 715 QENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKY 774 +E +L K E + + + L+ + + E+ + + + + +++ + I S + K+ Sbjct: 926 KEQKELLIKQESLKGQ-VERLMKDLENSEKRIHEVKQTLTQQSGDQEAEFQQIISNVKKH 984 Query: 775 -KSRICRLEESIAVMEDRRYSLERKADQ-LGSYLQEKQKAYSEYTIQEDELVNRLAVLMD 832 + I +L E E + +LE++ Q L EK ++ + DE+ + L Sbjct: 985 SEENIKKLNEE---KEQIKINLEKRLQQSLLQVTGEKDNEINQLQQRIDEMQQHIENLCQ 1041 Query: 833 HDRVVEKQLLEIEHENKEL----QKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDL 888 E+ LL E++ ++ Q L+E+ L+ L +M++ N VE+ R Sbjct: 1042 QH---EEVLLRAENDKQQALLIAHHDQQALMEK---LETVLHEMEEEKNN-VERVKREAA 1094 Query: 889 AESESTKYQ-TQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIE-FNTQIESAIRDKKVL 946 ++E + QLRD + LK E + ++K ++ DL+IE + E A R+ + L Sbjct: 1095 VKTEQERNNINQLRDELNRLKTKLDETRLKTDEEKIKL-DLKIEELWKERELAQRESEEL 1153 Query: 947 NEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQ 1006 + + V L+ QL E +++ E L K EL+D +++Q S E+ Sbjct: 1154 QVQLHMTEDKVDSLQNQLHETIRKLKDAENLNETLRK---ELVD--IRRQLGDSTYEKEK 1208 Query: 1007 YINEINKLNALLKQKDEEIIALNQKINNA--QVSYMS-MVSDYESKLAQFTTKLENMEEE 1063 Y + +L +K+ + E N+ + + ++S + M + +++ ++ ++ +ME+E Sbjct: 1209 YNSSNKELREHVKRIESEKREQNRILEESYQKISALEDMKVNVDAERSRLQAQIRDMEKE 1268 Query: 1064 MQRVSKQL-LDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMS 1122 M ++ KQL + + Q + Q+D+ KEL + +LT E E + + + Sbjct: 1269 MLQLQKQLHFTQDELQKSHQSNAQAQNDE-KEL-QARLTNETE----ERERLQLQLHQVK 1322 Query: 1123 DDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLN 1182 +VD L+ + +EE ER ++EQ + E C + ++ + N Sbjct: 1323 KQLMDVDNSLKVTRQELGRLRSRADEE--NERWRVREQELVVRLEDSRCRERKLEDQKHN 1380 Query: 1183 TELTGHDVVNQEQINQLKSKL-------EQLNTENDNLLSTVAELRSSISSAVDQRGFEI 1235 E+ D +QI +LK++L L+ + L T E+ +SS V I Sbjct: 1381 LEVCLADA--SQQIQELKARLGGSEGRVRALDAQLSQLEITKKEVEQKLSS-VGSTLRRI 1437 Query: 1236 AELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVT--MEQVT 1293 A + + + D + E K V M+QV Sbjct: 1438 AGIQMDGSVNIPFKLLSPSRRWSPARGTSQDHIDSSRDVILDVDPEIIRKGVRSLMQQVA 1497 Query: 1294 SLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLR 1353 ++ + D + L NL+++ + NQ RS+I+ + Sbjct: 1498 QIERERDDYKTELCNLKKQLDE--NQEIQNRSDIQINTLLTNIRMLQDEKNSLEVKL--- 1552 Query: 1354 TENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKD 1413 ++ QS +MQ ++ +EE QL++ N++E K+ Q E K Sbjct: 1553 SQKQSGYEMQLNALQLKSEECEQLREKIINLELMIS------NNSEEKI-----QFEEKL 1601 Query: 1414 SEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEK---ESELAILRLKMHENA 1470 ++ Q L + +E N++++L + E R L ++ E +L L++ E Sbjct: 1602 DKLKQ-------VLNKVENEKRNLQEELSKSESRATKLELQRMSLEGDLQRLQMMFQEKD 1654 Query: 1471 NHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQE 1530 + +Q+ ++ + + + L + T SL V +LN ALE+ NE++ + + + Sbjct: 1655 ANIHKLQERNDTQN-RTMTTLEERCT---SLKSMVEQLNLALEKASTTENELKNEINSMQ 1710 Query: 1531 IEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLD 1582 I+ L T LQ + ++QK +S A + ++ E+++ +M + L D Sbjct: 1711 HNIMELT---TTLQTS-NEKNKQLQKQISNAENERRILSERIE-SMQQSLND 1757 Score = 118 bits (285), Expect = 1e-24 Identities = 255/1316 (19%), Positives = 546/1316 (41%), Gaps = 108/1316 (8%) Query: 235 EKQRLLKDIESKDVR--ISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXX 292 E +R+L +E DV+ + LE E + + E K+ +E + Sbjct: 717 ELERVL--LEKSDVQEVLMKLETVCSNHEQEKQRLQEELKKVTEEKNKLANQCTDQQGDL 774 Query: 293 XXLAKQSIEPSCEEKTEIE-EKGSL-EIANMTELTKKIELLEHLNCQIRQTNKELENKLA 350 L K+ ++ + + ++E EK +L E E+ K E +E Q+ + + N+L+ Sbjct: 775 GSLRKELLQAE-QTRLDLESEKVTLNEKVKFLEIEK--EKIEIELAQVTRERGDFNNQLS 831 Query: 351 TMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKI----NKNE 406 + + + ++ L+ K A++M ++ + + + +K++ N+ E Sbjct: 832 VLARKKETLNEE------LMRLKQRLEQANEMNGRINRNLEDLVKDNEEKQVLLETNEKE 885 Query: 407 IAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLI 466 + +L+ + S+ + E V+ + T + +L ++ Q+ ++G Sbjct: 886 VQRLQEQLASMRSEKETLEGVLFDTQTSLENMHVKKTQLEKEQKELLIK-QESLKGQVER 944 Query: 467 HVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKS-AEEQITQLNDEIDAANKN 525 + I +V++ L Q+ D+ + + +I +K +EE I +LN+E K Sbjct: 945 LMKDLENSEKRIHEVKQTLTQQSGDQ--EAEFQQIISNVKKHSEENIKKLNEE-----KE 997 Query: 526 MIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAE--LEEEKGNLQL 583 IK+ +L+ +Q T + ++++ + I + + + +L Q+ E L E Q Sbjct: 998 QIKINLEKRLQQSLLQVTGEKDNEINQLQQRIDEMQQHIENLCQQHEEVLLRAENDKQQA 1057 Query: 584 HLVDYDSGRMIESDVYKKMIEME----NLAETRLKAISLLESQKFDLVQ---ELHILQQK 636 L+ + + + + + EME N+ + +A E ++ ++ Q EL+ L+ K Sbjct: 1058 LLIAHHDQQALMEKLETVLHEMEEEKNNVERVKREAAVKTEQERNNINQLRDELNRLKTK 1117 Query: 637 YDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLD--KEQLYG 694 DE K D +++ D +I+ + E ++ + + ++ L + K+D + QL+ Sbjct: 1118 LDETRLK-TDEEKIKLDL---KIEELWKERELAQRESEELQVQLHMTEDKVDSLQNQLHE 1173 Query: 695 TI---KDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQF 751 TI KD EN E + +L + ++ D T + EK ++ EL + E K + Sbjct: 1174 TIRKLKDAENLNETLRKELVDIRRQLGDSTYEKEKYNSSN-KELREHVKRIESEKREQNR 1232 Query: 752 GIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQK 811 ++ Q+ +E+++ + +SR L+ I ME L+++ LQ+ + Sbjct: 1233 ILEESYQKISA-LEDMKVNVDAERSR---LQAQIRDMEKEMLQLQKQLHFTQDELQKSHQ 1288 Query: 812 AYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSD 871 + ++ E EL RL + E++ L+++ Q K Q L++ + +L+++ + Sbjct: 1289 SNAQAQNDEKELQARLT-----NETEERERLQLQLH----QVKKQ-LMDVDNSLKVTRQE 1338 Query: 872 MQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIE 931 + + + E+ R + E E R E L+ H + + ++I++L+ Sbjct: 1339 LGRLRSRADEENERWRVREQELVVRLEDSRCRERKLEDQKHNLEVCLADASQQIQELKAR 1398 Query: 932 FNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDK 991 E +R + E + V Q + + I + M+ +N+ K Sbjct: 1399 LGGS-EGRVRALDAQLSQLEITKKEVEQKLSSVGSTLRRIAGIQMD----GSVNIPF--K 1451 Query: 992 HVQKQQTQSPDY-TEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMV-SDYESK 1049 + + SP T Q + I+ ++ D EII + QV+ + DY+++ Sbjct: 1452 LLSPSRRWSPARGTSQ--DHIDSSRDVILDVDPEIIRKGVRSLMQQVAQIERERDDYKTE 1509 Query: 1050 LAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKT 1109 L +L+ +E+Q S +++ N +++L E++ +L + + +EM + Sbjct: 1510 LCNLKKQLDE-NQEIQNRSDIQINTLLTN--IRMLQDEKNSLEVKLSQKQSGYEMQLNAL 1566 Query: 1110 EGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVL---QEQSAKLNT 1166 + + S E + + N++ K+Q EE+ + + VL + + L Sbjct: 1567 Q--LKSEECEQLREKIINLELMISNNSEE----KIQFEEKLDKLKQVLNKVENEKRNLQE 1620 Query: 1167 ELQECYTKIIQLETLNTELTGHDVVNQEQINQLKS----KLEQLNTENDNLLSTVAELRS 1222 EL + ++ +LE L G D+ + + Q K KL++ N + ++T+ E + Sbjct: 1621 ELSKSESRATKLELQRMSLEG-DLQRLQMMFQEKDANIHKLQERNDTQNRTMTTLEERCT 1679 Query: 1223 SISSAVDQRGF--EIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQ 1280 S+ S V+Q E A + L Q EL L K +QL + ++ Sbjct: 1680 SLKSMVEQLNLALEKASTTENELKNEINSMQHNIMELTTTLQTSNEKNKQLQKQISNA-- 1737 Query: 1281 EETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXX 1340 E + + E++ S+Q L D L++ + D I +++ + E ++ A Sbjct: 1738 -ENERRILSERIESMQQSLND----LKHTNQTLTDQITRLQNELANNEVQRCALESQLRI 1792 Query: 1341 XXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEA 1400 ++ + + +Q+Q I + K + R + + Sbjct: 1793 VAYPTQEE--NINKDEELLRQLQ---IAQRERSEMRGKMEALNDKMKLLEADKRNLERQL 1847 Query: 1401 KVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELA 1460 + + T++ K E Y+K H + + D +E ++L +R+E EKE+EL Sbjct: 1848 SLFKSTNRS--KSYERYEKAHTELLGTSFDIDHYEQENRELRLKVRRLETQLAEKEAELI 1905 Query: 1461 ILRLK-MHENANHYETMQKESEIERVKLIEELNVKITES--VSLNKQVAELNKALE 1513 L+ H ++ + EIER++ + K+ E+ S +QV L ++ Sbjct: 1906 RLKSSYTHTHSVFDFNRDRTGEIERLRAAQLQAEKLLEAREQSHRQQVLRLENQIQ 1961 Score = 97.9 bits (233), Expect = 2e-18 Identities = 178/969 (18%), Positives = 402/969 (41%), Gaps = 81/969 (8%) Query: 625 DLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVH-LEEQIDALSASKKELALVIE 683 DL EL L+Q+YD ++++ +++ +++ I+ VH LEE+ + + Sbjct: 396 DLKTELITLKQQYDVAQNEI----RIKEEKINQLIRDVHSLEERCGEAETEIHRNTRLQD 451 Query: 684 NLKLDKEQLYGTIKDLENDKEDI-MNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHE 742 ++++ + L + D E + Q ++ T + + S ++ + + N Sbjct: 452 DIEILQSALRDIAHAVIQDAESREIESTQAPPHLHLSPTGPIPQKSPKRGT----RSNTI 507 Query: 743 EQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQL 802 T + A + + L I ++ +L K ++ + E+ +LE+KA++L Sbjct: 508 PAFAESTISAVQAALHKYQLTIHELQVKLQTNKEQLQNTRKQCENAEENVKTLEKKAEEL 567 Query: 803 GSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEEN 862 L + S+ ++D L L + +EK +E+ + + L + L + N Sbjct: 568 IIELDAVRLHCSQLNQEKDMLQKGLDTIRIEKNTLEKTRIELNNMMENLNNDCEKLQKAN 627 Query: 863 QNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKK 922 LQ +++ L + NR +LR+L NL+ + + + Sbjct: 628 NKLQKICDNLEDEKLYLQSELNR--------LSKDVELREL--NLR----SEEDRCSKMR 673 Query: 923 KEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELN 982 +E+ L E N S K +L ++ + ++Q+E + + +E + + ++ Sbjct: 674 EELLTLREELNKTYLS----KDMLEQQKLETDGLISQIEKSKGDLELELERVLLEKSDVQ 729 Query: 983 K--MNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYM 1040 + M LE + + ++++ + + ++ E NKL + ++ +L +++ A+ + + Sbjct: 730 EVLMKLETVCSNHEQEKQRLQEELKKVTEEKNKLANQCTDQQGDLGSLRKELLQAEQTRL 789 Query: 1041 SMVSD---YESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKE 1097 + S+ K+ + E +E E+ +V+++ D N +L +L R+++ +EL Sbjct: 790 DLESEKVTLNEKVKFLEIEKEKIEIELAQVTRERGD---FNNQLSVLARKKETLNEELMR 846 Query: 1098 TKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEE-EEFIQERSV 1156 K E + G I+ +E + D N + ++QE+ E+ Sbjct: 847 LKQRLE-QANEMNGR-INRNLEDLVKD--NEEKQVLLETNEKEVQRLQEQLASMRSEKET 902 Query: 1157 LQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLST 1216 L+ T L+ + K QLE EL ++ QE LK ++E+L + +N Sbjct: 903 LEGVLFDTQTSLENMHVKKTQLEKEQKEL----LIKQE---SLKGQVERLMKDLENSEKR 955 Query: 1217 VAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQ 1276 + E++ +++ + E ++ E + +K E E + +Q L V Sbjct: 956 IHEVKQTLTQQSGDQEAEFQQIISNVKKHSEENIKKLNEEKEQIKINLEKRLQQSLLQV- 1014 Query: 1277 SSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXX 1336 T E+ N ++ LQ ++ + ++H+ NL +++ +V+ + E ++ + + Sbjct: 1015 --TGEKDN------EINQLQQRIDEMQQHIENLCQQHEEVLLRAE---NDKQQALLIAHH 1063 Query: 1337 XXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKK-SSXXXXXXXXXXXXRV 1395 ++ E + ++++ ++ + +E + + R+ Sbjct: 1064 DQQALMEKLETVLHEMEEEKNNVERVKREAAVKTEQERNNINQLRDELNRLKTKLDETRL 1123 Query: 1396 NDAEAKV-LELTHQLELKDSEIYQK-THEYTITLTQRNDEFENVRQQLVEYEKRIED--- 1450 E K+ L+L + K+ E+ Q+ + E + L D+ ++++ QL E ++++D Sbjct: 1124 KTDEEKIKLDLKIEELWKERELAQRESEELQVQLHMTEDKVDSLQNQLHETIRKLKDAEN 1183 Query: 1451 LTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNK 1510 L EL +R ++ ++ T +KE K + E +VK ES + E N+ Sbjct: 1184 LNETLRKELVDIRRQLGDS-----TYEKEKYNSSNKELRE-HVKRIES-----EKREQNR 1232 Query: 1511 ALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDE 1570 LEE K + ++ N + E L +I +++ ++QK + F D Q + Sbjct: 1233 ILEESYQKISALEDMKVNVDAERSRLQAQIRDMEK----EMLQLQKQLHFTQDELQKSHQ 1288 Query: 1571 QLDNTMNKE 1579 N E Sbjct: 1289 SNAQAQNDE 1297 Score = 96.7 bits (230), Expect = 5e-18 Identities = 275/1444 (19%), Positives = 573/1444 (39%), Gaps = 124/1444 (8%) Query: 147 LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXX 206 L NT K+ +NA ++ K E I++L Q+ + K+ Sbjct: 543 LQNTRKQCENAEENVKTLEKKAEELIIELDAVRLHCSQLNQEKDMLQKGLDTIRIEKNTL 602 Query: 207 XXXXXEDTKQQMTKMQENF---IAMEAEWKDEKQRLLKDIESKDVRISS-LEEANKLLEA 262 E T+ ++ M EN + ++ Q++ ++E + + + S L +K +E Sbjct: 603 -----EKTRIELNNMMENLNNDCEKLQKANNKLQKICDNLEDEKLYLQSELNRLSKDVEL 657 Query: 263 ARFEISLEH---SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIA 319 + E SK+ +EL L +Q +E + KG LE+ Sbjct: 658 RELNLRSEEDRCSKMREELLTLREELNKTYLSKDMLEQQKLETDGLISQIEKSKGDLELE 717 Query: 320 NMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTA 379 L +K ++ E L ++ E + + E K V+ K + + + G Sbjct: 718 LERVLLEKSDVQEVL-MKLETVCSNHEQEKQRLQEELKKVTEEKNKLANQCTDQQG--DL 774 Query: 380 SKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXX 439 ++ Q L+ +++K ++ LE+ + + +L V E+ Sbjct: 775 GSLRKELLQAEQTRLDLESEKVTLNEKVKFLEIEKEKIEIELAQ---VTRERGDFNNQLS 831 Query: 440 XXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVN-V 498 K+TL +L + +Q +E + ++ G ++ ++ K E+ + L K+V + Sbjct: 832 VLARKKETLNEEL-MRLKQRLEQANEMN-GRINRNLEDLVKDNEEKQVLLETNEKEVQRL 889 Query: 499 KDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIV 558 ++ + ++S +E + + + + +NM VK K +L++ QK + K ++ Sbjct: 890 QEQLASMRSEKETLEGVLFDTQTSLENM-HVK---KTQLEKEQKEL--LIKQESLKGQVE 943 Query: 559 RLTEELHHLSQKVAE----LEEEKGNLQLHLVDYDSG--RMIESDVYKKMIEMENLA--- 609 RL ++L + +++ E L ++ G+ + S + E ++ K E E + Sbjct: 944 RLMKDLENSEKRIHEVKQTLTQQSGDQEAEFQQIISNVKKHSEENIKKLNEEKEQIKINL 1003 Query: 610 ETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQID 669 E RL+ L + + D E++ LQQ+ DE++ + ++ Q Q ++V ++ ++Q Sbjct: 1004 EKRLQQSLLQVTGEKD--NEINQLQQRIDEMQQHIENLCQ-QHEEVLLRAEN---DKQQA 1057 Query: 670 ALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSA 729 L A + AL+ E L+ ++ ++E K + K + L D+L ++ Sbjct: 1058 LLIAHHDQQALM-EKLETVLHEMEEEKNNVERVKREAAVKTEQERNNINQLRDELNRLKT 1116 Query: 730 EKISELLAKINHEEQSKIQTQFGIDAKIQERDLY---IENIESELSKYKSRICRLEESIA 786 K+ E K + E KI+ I+ +ER+L E ++ +L + ++ L+ + Sbjct: 1117 -KLDETRLKTDEE---KIKLDLKIEELWKERELAQRESEELQVQLHMTEDKVDSLQNQLH 1172 Query: 787 VMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEH 846 + E + L L + ++ + T ++++ + L +H + +E + E Sbjct: 1173 ETIRKLKDAENLNETLRKELVDIRRQLGDSTYEKEKYNSSNKELREHVKRIESEKREQNR 1232 Query: 847 ENKELQKKNQILLE-------ENQNLQISLSDMQQHYNALVEKANRT--DLAESESTKYQ 897 +E +K L + E LQ + DM++ L ++ + T +L +S + Q Sbjct: 1233 ILEESYQKISALEDMKVNVDAERSRLQAQIRDMEKEMLQLQKQLHFTQDELQKSHQSNAQ 1292 Query: 898 TQL--RDLESNLKRITHEHQTL---IVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEK 952 Q ++L++ L T E + L + Q KK++ D++ + R + +E+ E+ Sbjct: 1293 AQNDEKELQARLTNETEERERLQLQLHQVKKQLMDVDNSLKVTRQELGRLRSRADEENER 1352 Query: 953 NIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEIN 1012 +L +L++ + L E K NLE+ +Q + + Sbjct: 1353 WRVREQELVVRLEDSRCRERKL-----EDQKHNLEVCLADASQQIQELKARLGGSEGRVR 1407 Query: 1013 KLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLL 1072 L+A L Q + + QK+++ + + KL + +R S Sbjct: 1408 ALDAQLSQLEITKKEVEQKLSSVGSTLRRIAGIQMDGSVNIPFKLLSPS---RRWSPARG 1464 Query: 1073 DSKQHNEELQILVREQDDQI-----KELKE--TKLTFEMNIPKTEGMIISSTIEPMSDDA 1125 S+ H + + ++ + D +I + L + ++ E + KTE + ++ + Sbjct: 1465 TSQDHIDSSRDVILDVDPEIIRKGVRSLMQQVAQIERERDDYKTELCNLKKQLDENQEIQ 1524 Query: 1126 NNVDXXXXXXXXXXXXLKVQE---EEEFIQERSVLQEQSAKLNTELQECYT---KIIQLE 1179 N D L+ ++ E + Q++S + Q L + +EC KII LE Sbjct: 1525 NRSDIQINTLLTNIRMLQDEKNSLEVKLSQKQSGYEMQLNALQLKSEECEQLREKIINLE 1584 Query: 1180 TLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELW 1239 + + + + +E++++LK L ++ E NL +++ S + QR +L Sbjct: 1585 LMISNNSEEKIQFEEKLDKLKQVLNKVENEKRNLQEELSKSESRATKLELQRMSLEGDLQ 1644 Query: 1240 KQ-----------HLAQREADFQ-KTEHELRVQLSAFESKYEQL---LDSVQSSTQEETN 1284 + H Q D Q +T L + ++ +S EQL L+ ++ E N Sbjct: 1645 RLQMMFQEKDANIHKLQERNDTQNRTMTTLEERCTSLKSMVEQLNLALEKASTTENELKN 1704 Query: 1285 KIVTMEQ-VTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXX 1343 +I +M+ + L LQ E + LQ++ ++ N+ IL IE + + Sbjct: 1705 EINSMQHNIMELTTTLQTSNEKNKQLQKQISNAENERRILSERIESMQQSLN-------- 1756 Query: 1344 XXXXXXXDLRTENQSYK-QMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKV 1402 DL+ NQ+ Q+ N E + S +N E Sbjct: 1757 -------DLKHTNQTLTDQITRLQNELANNEVQRCALESQLRIVAYPTQEENINKDE--- 1806 Query: 1403 LELTHQLELKD---SEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESEL 1459 EL QL++ SE+ K + + N+ +QL ++ +YE+ + Sbjct: 1807 -ELLRQLQIAQRERSEMRGKMEALNDKMKLLEADKRNLERQLSLFKSTNRSKSYERYEKA 1865 Query: 1460 AILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKT 1519 L + +HYE +E ++ +L +L K E + L + + +T Sbjct: 1866 HTELLGTSFDIDHYEQENRELRLKVRRLETQLAEKEAELIRLKSSYTHTHSVFDFNRDRT 1925 Query: 1520 NEMQ 1523 E++ Sbjct: 1926 GEIE 1929 Score = 95.5 bits (227), Expect = 1e-17 Identities = 237/1264 (18%), Positives = 533/1264 (42%), Gaps = 136/1264 (10%) Query: 147 LSNTIKEKDNALSVLQVKMKIMETTILDLQ-EKI--NEKDQIIEAKNKATTXXXXXXXXX 203 L+N ++ L L+ ++ E T LDL+ EK+ NEK + +E + + Sbjct: 763 LANQCTDQQGDLGSLRKELLQAEQTRLDLESEKVTLNEKVKFLEIEKEKIEIELAQVTRE 822 Query: 204 XXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAA 263 D Q++ + + E KQRL + E +LE+ K E Sbjct: 823 RG-------DFNNQLSVLARKKETLNEELMRLKQRLEQANEMNGRINRNLEDLVKDNEEK 875 Query: 264 RFEISLEHSKLAQELEQXXXXXXXXXXXXXXL--AKQSIEPSCEEKTEIEEKGSLEIANM 321 + + ++ + EQ L + S+E +KT++E++ + Sbjct: 876 QVLLETNEKEVQRLQEQLASMRSEKETLEGVLFDTQTSLENMHVKKTQLEKEQKELLIKQ 935 Query: 322 TELTKKIELL----EHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRN 377 L ++E L E+ +I + + L + E + + S KK S +K Sbjct: 936 ESLKGQVERLMKDLENSEKRIHEVKQTLTQQSGDQEAEFQQIISNVKKHSEENIKKLNEE 995 Query: 378 TASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVD-----KEYVISEKD 432 ++K + ++L Q T +K NEI +L+ I + + + + +E ++ ++ Sbjct: 996 K-EQIKINLEKRLQQSLLQVTGEK--DNEINQLQQRIDEMQQHIENLCQQHEEVLLRAEN 1052 Query: 433 TXXXXXXXXXXGKDTLIAQLQ-LEHQQHMEGPSLIHV----GTNTE-DVNEIAKVQEQLK 486 + L+ +L+ + H+ E ++ V TE + N I +++++L Sbjct: 1053 DKQQALLIAHHDQQALMEKLETVLHEMEEEKNNVERVKREAAVKTEQERNNINQLRDELN 1112 Query: 487 QELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKL---KLKQMQKT 543 + L ++ + +K EK+K + +I +L E + A + +++ + K+ +Q Sbjct: 1113 R-LKTKLDETRLKTDEEKIK-LDLKIEELWKERELAQRESEELQVQLHMTEDKVDSLQNQ 1170 Query: 544 I-DNFSKVSDSNKEIVRLTEELHHLSQKVAE--LEEEKGN-----LQLHLVDYDSGRMIE 595 + + K+ D+ L +EL + +++ + E+EK N L+ H+ +S + + Sbjct: 1171 LHETIRKLKDAENLNETLRKELVDIRRQLGDSTYEKEKYNSSNKELREHVKRIESEKREQ 1230 Query: 596 SDV----YKKMIEMENL-----AE-TRLKA-ISLLESQKFDLVQELHILQQKYDEVEDKL 644 + + Y+K+ +E++ AE +RL+A I +E + L ++LH Q DE++ Sbjct: 1231 NRILEESYQKISALEDMKVNVDAERSRLQAQIRDMEKEMLQLQKQLHFTQ---DELQKSH 1287 Query: 645 ADISQLQSDQVCSEIKSVHLEEQIDALSAS----KKELALVIENLKLDKEQLYGTIK--- 697 +Q Q+D+ + + + E+ + L KK+L V +LK+ +++L G ++ Sbjct: 1288 QSNAQAQNDEKELQARLTNETEERERLQLQLHQVKKQLMDVDNSLKVTRQEL-GRLRSRA 1346 Query: 698 DLENDK-----EDIMNKLQNYIQENMDLTDKLEKM------SAEKISELLAKINHEEQSK 746 D EN++ ++++ +L++ L D+ + ++++I EL A++ E + Sbjct: 1347 DEENERWRVREQELVVRLEDSRCRERKLEDQKHNLEVCLADASQQIQELKARLGGSE-GR 1405 Query: 747 IQTQFGIDAKIQERDLYIENIESELSKYKSRICRLE----ESIAVMEDRRYSLERKADQL 802 ++ +DA++ + ++ + +E +LS S + R+ + + + S R+ Sbjct: 1406 VRA---LDAQLSQLEITKKEVEQKLSSVGSTLRRIAGIQMDGSVNIPFKLLSPSRRWSPA 1462 Query: 803 GSYLQEKQKAYSEYTIQEDELVNRLAV--LMDHDRVVEKQLLEIEHENKELQKKNQILLE 860 Q+ + + + D + R V LM +E++ + + E L+K+ L+ Sbjct: 1463 RGTSQDHIDSSRDVILDVDPEIIRKGVRSLMQQVAQIERERDDYKTELCNLKKQ----LD 1518 Query: 861 ENQNLQ----ISLSDMQQHYNALVEKANRTDLAESESTK-YQTQLRDLESNLKRITHEHQ 915 ENQ +Q I ++ + + L ++ N ++ S+ Y+ QL L+ + + Sbjct: 1519 ENQEIQNRSDIQINTLLTNIRMLQDEKNSLEVKLSQKQSGYEMQLNALQLKSEECEQLRE 1578 Query: 916 TLI---------VQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQE 966 +I ++K + E+ + + +K+ L E+ K+ T+LE Q Sbjct: 1579 KIINLELMISNNSEEKIQFEEKLDKLKQVLNKVENEKRNLQEELSKSESRATKLELQRMS 1638 Query: 967 YKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEII 1026 + +++ L M +E D ++ K Q ++ D + + + + LK E++ Sbjct: 1639 LEGDLQRLQMMFQEK--------DANIHKLQERN-DTQNRTMTTLEERCTSLKSMVEQLN 1689 Query: 1027 ALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVR 1086 +K + + + ++ + + + TT L+ E+ +++ KQ+ +++ L + Sbjct: 1690 LALEKASTTENELKNEINSMQHNIMELTTTLQTSNEKNKQLQKQISNAENERRILSERIE 1749 Query: 1087 EQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQE 1146 + +LK T T I + + + ++ ++ + ++ + + Sbjct: 1750 SMQQSLNDLKHTNQTLTDQITRLQNELANNEVQRCA-----LESQLRIVAYPTQEENINK 1804 Query: 1147 EEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQL 1206 +EE +++ + Q + +++ +++ K+ LE L + + N+ KS E+ Sbjct: 1805 DEELLRQLQIAQRERSEMRGKMEALNDKMKLLEADKRNLE-RQLSLFKSTNRSKS-YERY 1862 Query: 1207 NTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFES 1266 + LL T S +D E EL L R + Q E E +L +S Sbjct: 1863 EKAHTELLGT--------SFDIDHYEQENREL---RLKVRRLETQLAEKE--AELIRLKS 1909 Query: 1267 KYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSE 1326 Y SV ++ T +I + KL + E ++ +++ + NQI++LR + Sbjct: 1910 SYTH-THSVFDFNRDRTGEIERLRAAQLQAEKLLEARE--QSHRQQVLRLENQIQLLREQ 1966 Query: 1327 IEDE 1330 + E Sbjct: 1967 LNQE 1970 Score = 86.2 bits (204), Expect = 7e-15 Identities = 196/1086 (18%), Positives = 454/1086 (41%), Gaps = 77/1086 (7%) Query: 58 QKCLENAALVSKRIKEHRKATAELLGRPFVPGISESLANTLKQKEILMEKIKQYKELSKR 117 Q LEN + ++++ +K L+ + + G E L L+ E + ++KQ Sbjct: 911 QTSLENMHVKKTQLEKEQKEL--LIKQESLKGQVERLMKDLENSEKRIHEVKQTLTQQSG 968 Query: 118 SSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQE 177 + +L + EK S+LQV + + I LQ+ Sbjct: 969 DQEAEFQQIISNVKKHSEENIKKLNEEKEQIKINLEKRLQQSLLQVTGE-KDNEINQLQQ 1027 Query: 178 KINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQ 237 +I+E Q IE + +Q + + E + E K+ + Sbjct: 1028 RIDEMQQHIENLCQQHEEVLLRAENDKQQALLIAHHDQQALMEKLETVLHEMEEEKNNVE 1087 Query: 238 RLLKDIESKDVRISSLEEANKLL-EAARFEISLEHSKLAQELEQXXXXXXXXXX-XXXXL 295 R+ ++ K + N+L E R + L+ ++L + E+ L Sbjct: 1088 RVKREAAVKTEQ--ERNNINQLRDELNRLKTKLDETRLKTDEEKIKLDLKIEELWKEREL 1145 Query: 296 AKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTE 355 A++ E + E+K + E +K++ E+LN +R+ ++ +L E Sbjct: 1146 AQRESEELQVQLHMTEDKVDSLQNQLHETIRKLKDAENLNETLRKELVDIRRQLGDSTYE 1205 Query: 356 SKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKN-EIAKLEMVI 414 + +S +K+ + R + ++ + S + ++ D K+N + E ++L+ I Sbjct: 1206 KEKYNSSNKELREHVKRIESEK---REQNRILEESYQKISALEDMKVNVDAERSRLQAQI 1262 Query: 415 QSLNKDLVDKE----YVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIH-VG 469 + + K+++ + + E + L A+L E ++ +H V Sbjct: 1263 RDMEKEMLQLQKQLHFTQDELQKSHQSNAQAQNDEKELQARLTNETEERERLQLQLHQVK 1322 Query: 470 TNTEDVNEIAKVQEQ----LKQELNDEIKDVNVKD--LIEKLKSAEEQITQLNDE----- 518 DV+ KV Q L+ ++E + V++ L+ +L+ + + +L D+ Sbjct: 1323 KQLMDVDNSLKVTRQELGRLRSRADEENERWRVREQELVVRLEDSRCRERKLEDQKHNLE 1382 Query: 519 --IDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEE 576 + A++ + ++K+ +++ S++ + KE+ + + +++A ++ Sbjct: 1383 VCLADASQQIQELKARLGGSEGRVRALDAQLSQLEITKKEVEQKLSSVGSTLRRIAGIQM 1442 Query: 577 EKG-NLQLHLVD---------------YDSGRMIESDVYKKMIEMENLAETRLKAISLLE 620 + N+ L+ DS R + DV ++I + ++ ++ +E Sbjct: 1443 DGSVNIPFKLLSPSRRWSPARGTSQDHIDSSRDVILDVDPEIIRKG--VRSLMQQVAQIE 1500 Query: 621 SQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELA- 679 ++ D EL L+++ DE ++ + + S +Q + + + I+ + E+ + S+K+ Sbjct: 1501 RERDDYKTELCNLKKQLDENQE-IQNRSDIQINTLLTNIRMLQDEKNSLEVKLSQKQSGY 1559 Query: 680 -LVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQ--ENMD-LTDKLEKMSAEK--IS 733 + + L+L E+ + + N + I N + IQ E +D L L K+ EK + Sbjct: 1560 EMQLNALQLKSEECEQLREKIINLELMISNNSEEKIQFEEKLDKLKQVLNKVENEKRNLQ 1619 Query: 734 ELLAKINHEEQSKIQTQ-FGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRR 792 E L+K + +K++ Q ++ +Q + + ++ + K + R ++ +E+R Sbjct: 1620 EELSK-SESRATKLELQRMSLEGDLQRLQMMFQEKDANIHKLQERNDTQNRTMTTLEERC 1678 Query: 793 YSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQ 852 SL+ +QL L++ +E + + + + + L + ++ +++ + + Sbjct: 1679 TSLKSMVEQLNLALEKASTTENELKNEINSMQHNIMELTTTLQTSNEKNKQLQKQISNAE 1738 Query: 853 KKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITH 912 + +IL E +++Q SL+D++ L ++ R ++E + Q LES L+ + + Sbjct: 1739 NERRILSERIESMQQSLNDLKHTNQTLTDQITR---LQNELANNEVQRCALESQLRIVAY 1795 Query: 913 EHQTLIVQKKKEIEDLEIEFNTQIESAIRDK-KVLNEKYEKNIEYVTQLEAQLQEYKNNI 971 Q + K +E+ +++ + S +R K + LN+K + LE QL +K+ Sbjct: 1796 PTQEENINKDEELL-RQLQIAQRERSEMRGKMEALNDKMKLLEADKRNLERQLSLFKST- 1853 Query: 972 ENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQK 1031 N + + E K + EL+ + + + ++ +L L +K+ E+I L Sbjct: 1854 -NRSKSYERYEKAHTELLGTSFDIDHYEQEN--RELRLKVRRLETQLAEKEAELIRL--- 1907 Query: 1032 INNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQ 1091 + ++ V D+ T ++E + Q +++LL++++ + Q+L ++Q Sbjct: 1908 --KSSYTHTHSVFDFN---RDRTGEIERL-RAAQLQAEKLLEAREQSHRQQVL--RLENQ 1959 Query: 1092 IKELKE 1097 I+ L+E Sbjct: 1960 IQLLRE 1965 >UniRef50_UPI0000ECA83C Cluster: Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).; n=2; Gallus gallus|Rep: Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1). - Gallus gallus Length = 2424 Score = 123 bits (297), Expect = 4e-26 Identities = 230/1151 (19%), Positives = 485/1151 (42%), Gaps = 88/1151 (7%) Query: 220 KMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELE 279 KM EN E E E++ +L ++ +D +EE L A+ K QEL Sbjct: 944 KMVENMHKEEMENIKEEKNIL--LQQRDDLQKQVEELTSQLAASEESHQAIGHKAQQELS 1001 Query: 280 QXXXXXXXXXXXXXXLAKQSIEPSCEEKT----EIEEKGSLEIANMTELTKKIELLEHLN 335 + ++ + S E+K +EE ++ +++L I+ + L+ Sbjct: 1002 EAQELSRQKALESE---RERLSLSLEQKELSLKTLEENNLVQQNEVSKLHSAIQQAQQLH 1058 Query: 336 CQIRQTNKELENKLATMGTE--SKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSET 393 R+ +EL N++ T+ K S +++ L + R ++ L +E Sbjct: 1059 SDHRREIQELNNQVQTLQEVVLEKEASLAAREKQLLQDLEESRAGERCLRDSLHVLEAEM 1118 Query: 394 LNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQ 453 +N L Q N + + + + K + Sbjct: 1119 AELHLRLCSTENRAKALATECQQANNAHCEAQSQLDKLHLVLHHVLCDSTDKSRDLVAWS 1178 Query: 454 LEHQQHMEGPSLIHV-GTNTE-DVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQ 511 E Q H+ G ++ + E V+ +A + L+Q+L +D+N D +K++ E + Sbjct: 1179 SE-QDHVWGLTVSQAKDLHVELTVDRVAAALQDLRQDLKQTQQDLN--DAGKKVQDLELE 1235 Query: 512 ITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNF-SKVSDSNKEIVRLTEELHHLSQK 570 +++ E D + + +++ +L Q Q+ + ++ + KE + L +E+ L +K Sbjct: 1236 LSKRQAERDHFSAHNQELQK----QLAQSQEVFSGWKAEAAALKKEAITLHQEVASLERK 1291 Query: 571 VAELEEEKGNLQLHLVDYDSGRMIESDVY---KKMIEMENLAETRLK-AISLLESQKFDL 626 + E++K ++ LH + D + +E + K + E +ETR A + S + +L Sbjct: 1292 LESAEKQKKDV-LH--ERDRLQAVEEKLMWEIKILQESVTASETRANTAADMNHSLEQEL 1348 Query: 627 VQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELAL------ 680 L +L+ K EV+ + I LQ + + +L + LS + E+ L Sbjct: 1349 QTTLSVLKTKNKEVDAQWEKIQMLQKEAADVKALQENLIQVNAILSKREGEMKLYQEQMR 1408 Query: 681 VIENLK-LDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKI 739 ++EN K + K L IKD++ KE ++ Q IQE ++ +L++ K+S+ L Sbjct: 1409 MLENQKEMHKTTLDQVIKDIKEKKEKTESQ-QEQIQE-LEKQQELQRTVISKMSKDLEDR 1466 Query: 740 NHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKA 799 + E +S+ + + ++ + + + + + +L+ I +E I +E R L+R A Sbjct: 1467 DKEIRSQQEEIWELEKQQELQRTVVSKMTKDLAHRDQEIQSQQEEIQELEKER-ELQRTA 1525 Query: 800 DQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRV-VEKQLLEIEHENKELQKKNQIL 858 S + + K E + EL+ L + R + K +E ++E++ + +++ Sbjct: 1526 ---ASKMSKDLKERDEKIRSQQELIEELEKQQELQRTALSKMSKNLEERDQEIKSQQELI 1582 Query: 859 LEENQNLQISLSDMQQHYNALVEKAN--RTDLAESESTKYQTQL-RDLESNLKRITHEHQ 915 E + ++ + + + L E+ R+ E + + Q +L R + S + + E Sbjct: 1583 EELKKQQELQRTAVSKMNKDLEERDQEIRSQQEEIQELEKQRELQRTILSKMSKDLEEKD 1642 Query: 916 TLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKY-EKNIEYVT--QLEAQLQEYKNNIE 972 +I ++ ++ LE +Q+ S + D + EKN+E ++ Q +L+ + ++ Sbjct: 1643 QVIKFQEGKVMILEQHGTSQVRSLLVDLDHMKGNLKEKNLELMSLNQQIKELEMEREEVK 1702 Query: 973 NLNMNVEELNKMNLELIDKH-VQKQQT----QSPDYTEQYINE----INKLNALLKQKDE 1023 +L+ ++E+L + + ++ Q+ Q Q ++ E+Y+ E + K+ L +KD+ Sbjct: 1703 SLHTSLEQLRAVLRDRENESDSQRDQLRLFQQYKEHQEEYLQELQDKVEKMTLSLSKKDQ 1762 Query: 1024 EIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQI 1083 E+ + ++I A+ + +L Q L+ E + +Q + ++ E++ + Sbjct: 1763 ELESQQKQIQEAEEVMEKKLKTVCDQLEQTLETLKEKERLLDIQKQQTREYEEKTEQMNV 1822 Query: 1084 LVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLK 1143 L R+ + L+E L E E T + DD+ LK Sbjct: 1823 LCRDLEYTKAILREKDLMIESQKELIE------TFQKQEDDSMQ---QKEILQHLKGALK 1873 Query: 1144 VQEEEEFIQERS--VLQEQSAKLNTELQECYTKIIQ-LETLNTELTGHDVVNQEQINQLK 1200 QE+E + +E+ K T+ T I+Q L+ + L D ++I LK Sbjct: 1874 EQEQETLSLRKQCEAFKEKEEKHKTDQT---TAIVQKLQCAESSLAARD----QEIASLK 1926 Query: 1201 SKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQ 1260 +++L + ++ V L+ ++ ++ KQ +++ F E +V Sbjct: 1927 EHVQELQKQKESEAKQVKSLQQDLNKMSKTMKKNNLQILKQ--SEQINVFHICEESRKVA 1984 Query: 1261 LSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQI 1320 L + +++ L + V+ ++E N+ +L KLQ +EE L+ LQ + + Sbjct: 1985 LLSCQNQVSLLEEVVRK--RDEDNE--------TLLQKLQHQEEELKTLQNLQLMLSEKK 2034 Query: 1321 EILRSEIEDEK 1331 E ++ E+EK Sbjct: 2035 EEIKRHGEEEK 2045 Score = 120 bits (290), Expect = 3e-25 Identities = 224/1154 (19%), Positives = 480/1154 (41%), Gaps = 74/1154 (6%) Query: 456 HQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQL 515 HQQH++ SL+ + D + K++ +L+Q+L E+ + L + + + Sbjct: 409 HQQHLK--SLV-LALKC-DCENLEKIRGELQQKL--ELSEQEASRLRQSNTELQLKEDSA 462 Query: 516 NDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELE 575 E M + +H+L LK + + S + + E+V E+L + L+ Sbjct: 463 QGEKVEQQLAMERAHHDHELVLKDLAALEEKHSLLQN---ELVAAREKLEESHLQRDLLK 519 Query: 576 EEKGNLQLHLVDYDSGRMIESDVYKKM-IEMENLAETRLKAISLLESQKFDLVQELHILQ 634 +EK L + L + + K+ E+ +L K S+ E+ D V EL+ L Sbjct: 520 QEKHELTVALEKAEKSVAALTGAQNKLNSEIADLHTAAAKMSSINEALALDKV-ELNKLV 578 Query: 635 QKYDEVEDKLAD-ISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLY 693 + ++ + L+D +++++ +V + K + + L A K L +++ + +E+L Sbjct: 579 LQLEQENELLSDKVNEMERAKVSEQEKITLYKRTNEELCAEKSHLEKLLKKAEEQQEELQ 638 Query: 694 GTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKM--SAEKISELLAKINHEEQSKIQTQF 751 ++ L +KE+ + KL ++ + LE++ + + + +AK++ E++ + + Sbjct: 639 MQLRILAEEKEETLEKLNQVYRQQESASSGLEQLRQQSSRQEDAVAKVSKEKEFLVHEKA 698 Query: 752 GIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQK 811 ++ ++ + + + +L++ +S LE S+ + + LE QL L Sbjct: 699 ALEVRLAAVERDRQGLSEQLAEARSVKDTLESSLFEAQQQLSHLEITKSQLEIQLHT--- 755 Query: 812 AYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSD 871 +Q E++ + ++ E+ L++ E +N Q+ QI + N L++ +D Sbjct: 756 -----VVQAKEVIQGEVKCLQYELETERCLMKQEQKNM-AQRLIQIEEQHNNTLKLQQTD 809 Query: 872 MQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEI- 930 + N L++ + E + Q +L E +H+ + K+++ ++ Sbjct: 810 HEVEINKLLQ--DLASEREGRQLELQERLELWEKEKAEAEGQHEKKLFHMKEKVATMQAQ 867 Query: 931 --EFNTQIESAIRDKKVLNEKYEKN---IEYVTQLEAQLQEYKNNIENLNMNVEELNKMN 985 E T++ESA ++++L EK + +E + Q + +L E + +E L V+E + Sbjct: 868 QEEERTRVESA--NQEILTEKENEKKALLETLLQTQGELTEACHQLEQLRQEVKEQQEYE 925 Query: 986 LELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKIN-NAQVSYM-SMV 1043 + +K + + Q + + ++K + K+E+ I L Q+ + QV + S + Sbjct: 926 QNITEK--LQAELQETHCKIKMVENMHK-EEMENIKEEKNILLQQRDDLQKQVEELTSQL 982 Query: 1044 SDYESKLAQFTTKLENMEEEMQRVSKQ-LLDSKQHNEELQILVREQDDQIKELKETKLTF 1102 + E K + E Q +S+Q L+S++ E L + + +++ +K L+E L Sbjct: 983 AASEESHQAIGHKAQQELSEAQELSRQKALESER--ERLSLSLEQKELSLKTLEENNLVQ 1040 Query: 1103 EMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSA 1162 + + K I + SD + + +E +E+ +LQ+ Sbjct: 1041 QNEVSKLHS-AIQQAQQLHSDHRREIQELNNQVQTLQEVVLEKEASLAAREKQLLQDLEE 1099 Query: 1163 KLNTELQECYTKIIQ-LETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELR 1221 E C + LE EL + + L ++ +Q N + S + +L Sbjct: 1100 SRAGE--RCLRDSLHVLEAEMAELHLRLCSTENRAKALATECQQANNAHCEAQSQLDKLH 1157 Query: 1222 SSISSAVDQRGFEIAEL--W---KQHLAQREADFQKTEH-ELRV-QLSAFESKYEQLLDS 1274 + + + +L W + H+ K H EL V +++A Q L Sbjct: 1158 LVLHHVLCDSTDKSRDLVAWSSEQDHVWGLTVSQAKDLHVELTVDRVAAALQDLRQDLKQ 1217 Query: 1275 VQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAF 1334 Q + K+ +E S K Q + +H ++ + Q + + S + E A Sbjct: 1218 TQQDLNDAGKKVQDLELELS---KRQAERDHFSAHNQELQKQLAQSQEVFSGWKAEAAAL 1274 Query: 1335 XXXXXXXXXXXXXXXXDLRT-ENQSYKQMQEQSILNINEE----NAQLKKSSXXXXXXXX 1389 L + E Q + E+ L EE ++ + S Sbjct: 1275 KKEAITLHQEVASLERKLESAEKQKKDVLHERDRLQAVEEKLMWEIKILQESVTASETRA 1334 Query: 1390 XXXXRVNDAEAKVLELT-HQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRI 1448 +N + + L+ T L+ K+ E+ + + + L + + + +++ L++ + Sbjct: 1335 NTAADMNHSLEQELQTTLSVLKTKNKEVDAQWEKIQM-LQKEAADVKALQENLIQ----V 1389 Query: 1449 EDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAEL 1508 + ++E E+ + + +M N E M K + + +K I+E K TE S +Q+ EL Sbjct: 1390 NAILSKREGEMKLYQEQMRMLENQKE-MHKTTLDQVIKDIKEKKEK-TE--SQQEQIQEL 1445 Query: 1509 NKALEEEVAKTNEMQTALENQEIEIVTLNDEITNL---QNMVRASSSKIQKHVSFASDTK 1565 K E + ++M LE+++ EI + +EI L Q + R SK+ K ++ Sbjct: 1446 EKQQELQRTVISKMSKDLEDRDKEIRSQQEEIWELEKQQELQRTVVSKMTKDLAHRDQEI 1505 Query: 1566 QGRDEQLDNTMNKE 1579 Q + E++ + KE Sbjct: 1506 QSQQEEIQE-LEKE 1518 Score = 119 bits (287), Expect = 6e-25 Identities = 289/1571 (18%), Positives = 637/1571 (40%), Gaps = 116/1571 (7%) Query: 49 ERQIKFERAQKCLENAALVSKRIKEHRKATAELLGRPFVPGISESLANTLKQKEILMEKI 108 E + E+A+K + AAL + K + + + I+E+LA + L+ ++ Sbjct: 524 ELTVALEKAEKSV--AALTGAQNKLNSEIADLHTAAAKMSSINEALALDKVELNKLVLQL 581 Query: 109 KQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQ---LGDVTHLSNTIKEKDNALSVLQVKM 165 +Q EL + R + +HL +K+ + LQ+++ Sbjct: 582 EQENELLSDKVNEMERAKVSEQEKITLYKRTNEELCAEKSHLEKLLKKAEEQQEELQMQL 641 Query: 166 KIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENF 225 +I+ + EK+N Q+ + A++ ED +++K +E Sbjct: 642 RILAEEKEETLEKLN---QVYRQQESASS-----GLEQLRQQSSRQEDAVAKVSKEKEFL 693 Query: 226 IAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXX 285 + +A + + +D + +++ LE++ FE + S L E+ + Sbjct: 694 VHEKAALEVRLAAVERDRQGLSEQLAEARSVKDTLESSLFEAQQQLSHL--EITKSQLEI 751 Query: 286 XXXXXXXXXLAKQSIEPSCEEKTEIEEKGSL---EIANMTELTKKIELLEHLNCQIRQTN 342 Q E C + E+E + L E NM + +IE + +++QT+ Sbjct: 752 QLHTVVQAKEVIQG-EVKCLQ-YELETERCLMKQEQKNMAQRLIQIEEQHNNTLKLQQTD 809 Query: 343 KELE-NK-LATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSS-ETLNQDTD 399 E+E NK L + +E + ++ L ++ K + T+ + Sbjct: 810 HEVEINKLLQDLASEREGRQLELQERLELWEKEKAEAEGQHEKKLFHMKEKVATMQAQQE 869 Query: 400 KKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQH 459 ++ + E A E++ + N+ E ++ + + + + Q E++Q+ Sbjct: 870 EERTRVESANQEILTEKENEKKALLETLLQTQGELTEACHQLEQLRQEV--KEQQEYEQN 927 Query: 460 MEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEI 519 + + E +I V+ K+E+ + ++ N+ L+++ ++Q+ +L ++ Sbjct: 928 ITEKLQAEL---QETHCKIKMVENMHKEEMENIKEEKNI--LLQQRDDLQKQVEELTSQL 982 Query: 520 DAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAE---LEE 576 A+ ++ + + +L + Q+ + K +S +E + L+ E LS K E L + Sbjct: 983 AASEESHQAIGHKAQQELSEAQEL--SRQKALESERERLSLSLEQKELSLKTLEENNLVQ 1040 Query: 577 EKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQK 636 + +LH + + SD +++ E+ N +T + + LE + +E +LQ Sbjct: 1041 QNEVSKLHSA-IQQAQQLHSDHRREIQELNNQVQTLQEVV--LEKEASLAAREKQLLQ-- 1095 Query: 637 YDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTI 696 ++E+ A L+ E + L ++ + K LA + +Q Sbjct: 1096 --DLEESRAGERCLRDSLHVLEAEMAELHLRLCSTENRAKALA-------TECQQANNAH 1146 Query: 697 KDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQ-TQFGIDA 755 + ++ + + L + + ++ D + L S+E+ ++ + ++ T + A Sbjct: 1147 CEAQSQLDKLHLVLHHVLCDSTDKSRDLVAWSSEQDHVWGLTVSQAKDLHVELTVDRVAA 1206 Query: 756 KIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSE 815 +Q+ ++ + +L+ ++ LE ++ + R +L L + Q+ +S Sbjct: 1207 ALQDLRQDLKQTQQDLNDAGKKVQDLELELSKRQAERDHFSAHNQELQKQLAQSQEVFSG 1266 Query: 816 YTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQH 875 + + L L +E++L E + K++ + L + L + +Q+ Sbjct: 1267 WKAEAAALKKEAITLHQEVASLERKLESAEKQKKDVLHERDRLQAVEEKLMWEIKILQES 1326 Query: 876 YNALVEKAN-RTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNT 934 A +AN D+ S + QT L L++ K + + + + + +K+ + ++ N Sbjct: 1327 VTASETRANTAADMNHSLEQELQTTLSVLKTKNKEVDAQWEKIQMLQKEAADVKALQENL 1386 Query: 935 QIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQ 994 +AI K+ K + E + LE Q + +K ++ + +++E K E + +Q Sbjct: 1387 IQVNAILSKREGEMKLYQ--EQMRMLENQKEMHKTTLDQVIKDIKE-KKEKTESQQEQIQ 1443 Query: 995 KQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKI---NNAQVSYMSMVSDYESKLA 1051 + + Q E I+K++ L+ +D+EI + ++I Q ++VS LA Sbjct: 1444 ELEKQQ----ELQRTVISKMSKDLEDRDKEIRSQQEEIWELEKQQELQRTVVSKMTKDLA 1499 Query: 1052 QFTTKLENMEEEMQRV-----------SKQLLDSKQHNEEL---QILVREQDDQIKELKE 1097 ++++ +EE+Q + SK D K+ +E++ Q L+ E + Q +EL+ Sbjct: 1500 HRDQEIQSQQEEIQELEKERELQRTAASKMSKDLKERDEKIRSQQELIEELEKQ-QELQR 1558 Query: 1098 TKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSV- 1156 T L+ + I S E + + + L+ +++E Q+ + Sbjct: 1559 TALSKMSKNLEERDQEIKSQQELIEELKKQQELQRTAVSKMNKDLEERDQEIRSQQEEIQ 1618 Query: 1157 -LQEQSAKLNTELQECYTKIIQLETLNTELTGH-DVVNQEQINQLKSKLEQLNTENDNLL 1214 L++Q T L + + + + + G ++ Q +Q++S L L+ NL Sbjct: 1619 ELEKQRELQRTILSKMSKDLEEKDQVIKFQEGKVMILEQHGTSQVRSLLVDLDHMKGNLK 1678 Query: 1215 STVAELRSSISSAVDQRGFEIAELWKQH--LAQREADFQKTEHE---LRVQLSAFE---S 1266 EL S++ + + E E+ H L Q A + E+E R QL F+ Sbjct: 1679 EKNLEL-MSLNQQIKELEMEREEVKSLHTSLEQLRAVLRDRENESDSQRDQLRLFQQYKE 1737 Query: 1267 KYEQLLDSVQSSTQEETNKIVTMEQ-VTSLQNKLQDKEEHLRNLQEKYADVINQIE-ILR 1324 E+ L +Q ++ T + +Q + S Q ++Q+ EE +++K V +Q+E L Sbjct: 1738 HQEEYLQELQDKVEKMTLSLSKKDQELESQQKQIQEAEE---VMEKKLKTVCDQLEQTLE 1794 Query: 1325 SEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSY-------KQMQEQSILNINEENAQL 1377 + E E++ ++ + Y K + +S + E + Sbjct: 1795 TLKEKERLLDIQKQQTREYEEKTEQMNVLCRDLEYTKAILREKDLMIESQKELIETFQKQ 1854 Query: 1378 KKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLE-LKDSEIYQKTHEYTITLTQRNDEFEN 1436 + S + + E + L L Q E K+ E KT + T + + + Sbjct: 1855 EDDSMQQKEILQHLKGALKEQEQETLSLRKQCEAFKEKEEKHKTDQTTAIVQKLQCAESS 1914 Query: 1437 VR---QQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNV 1493 + Q++ ++ +++L +KESE ++ + ++ N K++ ++ +K E++NV Sbjct: 1915 LAARDQEIASLKEHVQELQKQKESEAKQVK-SLQQDLNKMSKTMKKNNLQILKQSEQINV 1973 Query: 1494 -KITES------VSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNM 1546 I E +S QV+ L + + + + L++QE E+ TL NLQ M Sbjct: 1974 FHICEESRKVALLSCQNQVSLLEEVVRKRDEDNETLLQKLQHQEEELKTLQ----NLQLM 2029 Query: 1547 VRASSSKIQKH 1557 + +I++H Sbjct: 2030 LSEKKEEIKRH 2040 Score = 110 bits (265), Expect = 3e-22 Identities = 277/1423 (19%), Positives = 584/1423 (41%), Gaps = 119/1423 (8%) Query: 215 KQQMTKMQENFIAMEAEWKDEKQRLL---------KDIESKDVRISSLEEANKLLEAA-R 264 ++++ M+E M+A+ ++E+ R+ K+ E K + + L+ +L EA + Sbjct: 851 EKKLFHMKEKVATMQAQQEEERTRVESANQEILTEKENEKKALLETLLQTQGELTEACHQ 910 Query: 265 FEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTE-IEEKGSLEIANMTE 323 E + K QE EQ + +E +E+ E I+E+ ++ + + Sbjct: 911 LEQLRQEVKEQQEYEQNITEKLQAELQETHCKIKMVENMHKEEMENIKEEKNILLQQRDD 970 Query: 324 LTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMK 383 L K++E L ++++ + +K +E++ +S + L S + + + + K Sbjct: 971 LQKQVEELTSQLAASEESHQAIGHKAQQELSEAQELS----RQKALESERERLSLSLEQK 1026 Query: 384 SPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXX 443 +LS +TL ++ + +NE++KL IQ + D I E + Sbjct: 1027 ----ELSLKTLEENN--LVQQNEVSKLHSAIQQAQQLHSDHRREIQELNNQVQTLQEVVL 1080 Query: 444 GKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIE 503 K+ A L +Q ++ D+ E + L+ L+ + + + +L Sbjct: 1081 EKE---ASLAAREKQLLQ------------DLEESRAGERCLRDSLH--VLEAEMAELHL 1123 Query: 504 KLKSAEEQITQLNDEIDAANKNMIKVKSN-HKLKLKQMQKTIDNFSKVSDSNKEIVRLTE 562 +L S E + L E AN + +S KL L D+ +D ++++V + Sbjct: 1124 RLCSTENRAKALATECQQANNAHCEAQSQLDKLHLVLHHVLCDS----TDKSRDLVAWSS 1179 Query: 563 ELHHL-SQKVAELEEEKGNLQLHLV---------DYDSGRMIESDVYKKMIEMENLAETR 612 E H+ V++ ++ L + V D + +D KK+ ++E R Sbjct: 1180 EQDHVWGLTVSQAKDLHVELTVDRVAAALQDLRQDLKQTQQDLNDAGKKVQDLELELSKR 1239 Query: 613 LKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALS 672 + +L ++L Q+ + + A+ + L+ + + + LE ++++ Sbjct: 1240 QAERDHFSAHNQELQKQLAQSQEVFSGWK---AEAAALKKEAITLHQEVASLERKLESAE 1296 Query: 673 ASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEK-MSAEK 731 KK++ + L+ +E+L IK L+ + N L +L+ +S K Sbjct: 1297 KQKKDVLHERDRLQAVEEKLMWEIKILQESVTASETRANTAADMNHSLEQELQTTLSVLK 1356 Query: 732 ISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDR 791 E+ +Q + D K + +L + + LSK + + +E + ++E++ Sbjct: 1357 TKNKEVDAQWEKIQMLQKE-AADVKALQENLI--QVNAILSKREGEMKLYQEQMRMLENQ 1413 Query: 792 RYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDR-VVEKQLLEIEHENKE 850 + + DQ+ ++EK+ E T + E + L + R V+ K ++E +KE Sbjct: 1414 KEMHKTTLDQVIKDIKEKK----EKTESQQEQIQELEKQQELQRTVISKMSKDLEDRDKE 1469 Query: 851 LQKKNQIL--LEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQL-RDLESNL 907 ++ + + + LE+ Q LQ ++ A ++ ++ E + + + +L R S + Sbjct: 1470 IRSQQEEIWELEKQQELQRTVVSKMTKDLAHRDQEIQSQQEEIQELEKERELQRTAASKM 1529 Query: 908 KRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEY 967 + E I +++ IE+LE + Q + + K L E+ + E +Q E ++E Sbjct: 1530 SKDLKERDEKIRSQQELIEELEKQQELQRTALSKMSKNLEERDQ---EIKSQQEL-IEEL 1585 Query: 968 KNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIA 1027 K E V ++NK +LE D+ ++ QQ + + +Q E+ + +L + +++ Sbjct: 1586 KKQQELQRTAVSKMNK-DLEERDQEIRSQQEEIQELEKQ--RELQR--TILSKMSKDLEE 1640 Query: 1028 LNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVRE 1087 +Q I + M + S++ L++M+ ++ + +L+ Q +EL++ E Sbjct: 1641 KDQVIKFQEGKVMILEQHGTSQVRSLLVDLDHMKGNLKEKNLELMSLNQQIKELEMEREE 1700 Query: 1088 QDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKV-QE 1146 L++ + +++ + + L + ++ Sbjct: 1701 VKSLHTSLEQLRAVLRDRENESDSQRDQLRLFQQYKEHQEEYLQELQDKVEKMTLSLSKK 1760 Query: 1147 EEEFIQERSVLQEQSAKLNTELQECYTKIIQ-LETLNTELTGHDVVNQEQINQLKSKLEQ 1205 ++E ++ +QE + +L+ ++ Q LETL + D+ Q Q + + K EQ Sbjct: 1761 DQELESQQKQIQEAEEVMEKKLKTVCDQLEQTLETLKEKERLLDIQKQ-QTREYEEKTEQ 1819 Query: 1206 LNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFE 1265 +N +L T A LR Q+ E+ E +++ Q + Q+ E ++ + E Sbjct: 1820 MNVLCRDLEYTKAILREKDLMIESQK--ELIETFQK---QEDDSMQQKEILQHLKGALKE 1874 Query: 1266 SKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRS 1325 + E L Q +E + +Q T++ KLQ E L ++ A + ++ L+ Sbjct: 1875 QEQETLSLRKQCEAFKEKEEKHKTDQTTAIVQKLQCAESSLAARDQEIASLKEHVQELQK 1934 Query: 1326 EIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXX 1385 + E E + Q KQ ++ ++ +I EE+ ++ S Sbjct: 1935 QKESEAKQVKSLQQDLNKMSKTMK---KNNLQILKQSEQINVFHICEESRKVALLSCQNQ 1991 Query: 1386 XXXXXXXXRVNDAEAKVL--ELTHQLE-LKDSEIYQKTHEYTITLTQRNDEFENVRQQLV 1442 R D + + L +L HQ E LK + Q +R+ E E ++ + Sbjct: 1992 VSLLEEVVRKRDEDNETLLQKLQHQEEELKTLQNLQLMLSEKKEEIKRHGEEEKFPEEAL 2051 Query: 1443 ---EYEKRIEDLTYEKESELAILRLKMHENANHYETM--QKESEI----ERVKLIE---- 1489 E+E + + +K+SE +R +HE+ + + +K+ EI +RVK +E Sbjct: 2052 HGSEWETKAQG--EQKKSEDEEIR-GLHEDLQYVQQTLTKKDEEIKYQRDRVKYLEKTLA 2108 Query: 1490 ---ELNVKITES-----VSLNKQVAELNKALEEEVA---KTNEMQTALENQEIEIVTLND 1538 EL ++ + L + +A L + E+ K + AL E+ TL + Sbjct: 2109 GQKELAQQLEDERKVKGEELKRVIAILKQTESGEIEWKEKAQALTLALSKSEMTNGTLRE 2168 Query: 1539 EITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELL 1581 EI LQ+MV + K + H+ + + + L N + K L Sbjct: 2169 EIAILQSMV-SERDKDRFHLQSSPELLKELQSLLLNQVQKASL 2210 Score = 109 bits (262), Expect = 6e-22 Identities = 241/1291 (18%), Positives = 531/1291 (41%), Gaps = 91/1291 (7%) Query: 328 IELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKK-GSPLISRKSGRNTASKM---- 382 I L+H + Q + K+L+ +L + E+K +S + S +++ K K+ Sbjct: 375 ISFLQHQHRQQEEKCKKLQQRLEQLEEENKMSNSHQQHLKSLVLALKCDCENLEKIRGEL 434 Query: 383 --KSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXX 440 K S+ + L Q + K + A+ E V Q L + ++ + KD Sbjct: 435 QQKLELSEQEASRLRQSNTELQLKEDSAQGEKVEQQLAMERAHHDHELVLKDLAALEEKH 494 Query: 441 XXXGKDTLIAQLQLEHQQHMEGPSL----IHVGTNTEDVNEIAKVQEQLKQELNDEIKDV 496 + + A+ +LE + H++ L + E + + +LN EI D+ Sbjct: 495 SLLQNELVAAREKLE-ESHLQRDLLKQEKHELTVALEKAEKSVAALTGAQNKLNSEIADL 553 Query: 497 NVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKL---KLKQMQKT-IDNFSKVSD 552 + K+ S E + D+++ NK +++++ ++L K+ +M++ + K++ Sbjct: 554 HT--AAAKMSSINEALAL--DKVE-LNKLVLQLEQENELLSDKVNEMERAKVSEQEKITL 608 Query: 553 SNKEIVRLTEELHHLSQ--KVAELEEEKGNLQLHLVDYDSGRMIE--SDVYKK------- 601 + L E HL + K AE ++E+ +QL ++ + +E + VY++ Sbjct: 609 YKRTNEELCAEKSHLEKLLKKAEEQQEELQMQLRILAEEKEETLEKLNQVYRQQESASSG 668 Query: 602 MIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVE-DKLA---DISQLQSDQVCS 657 + ++ + + A++ + +K LV E L+ + VE D+ +++ +S + Sbjct: 669 LEQLRQQSSRQEDAVAKVSKEKEFLVHEKAALEVRLAAVERDRQGLSEQLAEARSVKDTL 728 Query: 658 EIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIK----DLENDKEDIMNKLQNY 713 E ++Q+ L +K +L + + + KE + G +K +LE ++ + + +N Sbjct: 729 ESSLFEAQQQLSHLEITKSQLEIQLHTVVQAKEVIQGEVKCLQYELETERCLMKQEQKNM 788 Query: 714 IQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQER-DLYIENIESELS 772 Q + + ++ + ++ +IN Q + G ++QER +L+ + Sbjct: 789 AQRLIQIEEQHNNTLKLQQTDHEVEINKLLQDLASEREGRQLELQERLELWEKEKAEAEG 848 Query: 773 KYKSRICRLEESIAVM----EDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLA 828 +++ ++ ++E +A M E+ R +E ++ + + ++KA E +Q + Sbjct: 849 QHEKKLFHMKEKVATMQAQQEEERTRVESANQEILTEKENEKKALLETLLQTQGELTEAC 908 Query: 829 VLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDL 888 ++ R K+ E E + + +K Q L+E + +I + + H + ++ Sbjct: 909 HQLEQLRQEVKEQQEYE---QNITEKLQAELQET-HCKIKMVE-NMHKEEMENIKEEKNI 963 Query: 889 AESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEI-EDLEIEFNTQIESAIRDKKVLN 947 + Q Q+ +L S L HQ + + ++E+ E E+ +ES R++ L+ Sbjct: 964 LLQQRDDLQKQVEELTSQLAASEESHQAIGHKAQQELSEAQELSRQKALESE-RERLSLS 1022 Query: 948 EKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQY 1007 + +K + T E L + +N + L+ +++ +++ + + +Q+ Q E Sbjct: 1023 LE-QKELSLKTLEENNLVQ-QNEVSKLHSAIQQAQQLHSD-HRREIQELNNQVQTLQEVV 1079 Query: 1008 INEINKLNALLKQ--KD-EEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEM 1064 + + L A KQ +D EE A + + ++ + +++ +L + + + E Sbjct: 1080 LEKEASLAAREKQLLQDLEESRAGERCLRDSLHVLEAEMAELHLRLCSTENRAKALATEC 1139 Query: 1065 QRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDD 1124 Q+ + +++ ++L +++ + + + G+ +S + + Sbjct: 1140 QQANNAHCEAQSQLDKLHLVLHHVLCDSTDKSRDLVAWSSEQDHVWGLTVSQAKDLHVE- 1198 Query: 1125 ANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTE 1184 VD LK Q +++ +Q+ L EL + + N E Sbjct: 1199 -LTVDRVAAALQDLRQDLK-QTQQDLNDAGKKVQD----LELELSKRQAERDHFSAHNQE 1252 Query: 1185 LTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLA 1244 L +QE + K++ L E L VA L + SA Q+ + E + L Sbjct: 1253 LQKQLAQSQEVFSGWKAEAAALKKEAITLHQEVASLERKLESAEKQKKDVLHE--RDRLQ 1310 Query: 1245 QREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKE- 1303 E L+ ++A E++ D S QE + T V +NK D + Sbjct: 1311 AVEEKLMWEIKILQESVTASETRANTAADMNHSLEQE----LQTTLSVLKTKNKEVDAQW 1366 Query: 1304 EHLRNLQEKYADV------INQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQ 1357 E ++ LQ++ ADV + Q+ + S+ E E + L + Sbjct: 1367 EKIQMLQKEAADVKALQENLIQVNAILSKREGEMKLYQEQMRMLENQKEMHKTTLDQVIK 1426 Query: 1358 SYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQL-ELKDSEI 1416 K+ +E++ + E+ +L+K + D + ++ ++ EL+ + Sbjct: 1427 DIKEKKEKT-ESQQEQIQELEKQQELQRTVISKMSKDLEDRDKEIRSQQEEIWELEKQQE 1485 Query: 1417 YQKT--HEYTITLTQRNDEFENVRQQLVEYEKRIE---DLTYEKESELAILRLKMHENAN 1471 Q+T + T L R+ E ++ ++++ E EK E + +L K+ Sbjct: 1486 LQRTVVSKMTKDLAHRDQEIQSQQEEIQELEKERELQRTAASKMSKDLKERDEKIRSQQE 1545 Query: 1472 HYETMQKESEIERV---KLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALEN 1528 E ++K+ E++R K+ + L + E S + + EL K E + ++M LE Sbjct: 1546 LIEELEKQQELQRTALSKMSKNLEERDQEIKSQQELIEELKKQQELQRTAVSKMNKDLEE 1605 Query: 1529 QEIEIVTLNDEITNLQ---NMVRASSSKIQK 1556 ++ EI + +EI L+ + R SK+ K Sbjct: 1606 RDQEIRSQQEEIQELEKQRELQRTILSKMSK 1636 Score = 88.2 bits (209), Expect = 2e-15 Identities = 228/1182 (19%), Positives = 492/1182 (41%), Gaps = 129/1182 (10%) Query: 480 KVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQ 539 + Q+Q+++E+N E +V + E L+ E L D + + +++ + ++ K K Sbjct: 215 QAQQQVEREINQEALEVMCLQVDEDLEKKE-----LQDRVMELSALLVQSQKQNEEKEKT 269 Query: 540 MQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVY 599 + KT+++ ++ +++ RL E+ + + +EE LQ + + + +SD Sbjct: 270 V-KTLNDTVEMLEAS----RL--EVEYEASLTKNAKEENLALQKLIKEITEVVLDDSDST 322 Query: 600 KKMIEMENLAETRLKAISLLESQK-FDLVQELHILQQKY-----DEVEDKLADISQLQSD 653 +++ + L +S L+++ F LVQE +QK +E+ + IS LQ Sbjct: 323 VGIVQRPESSNV-LSCLSSLDAEHAFVLVQETLARRQKAIQALKEELSTRQDSISFLQHQ 381 Query: 654 QVCSEIKSVHLEEQIDALSASKK-------ELALVIENLKLDKEQLYGTIKDLENDKEDI 706 E K L+++++ L K L ++ LK D E L +L+ E Sbjct: 382 HRQQEEKCKKLQQRLEQLEEENKMSNSHQQHLKSLVLALKCDCENLEKIRGELQQKLELS 441 Query: 707 MNKLQNYIQENMDLTDKLEKMSAEKISELLA--KINH-------------EEQSKIQTQF 751 + Q N +L K + EK+ + LA + +H E+ S +Q + Sbjct: 442 EQEASRLRQSNTELQLKEDSAQGEKVEQQLAMERAHHDHELVLKDLAALEEKHSLLQNEL 501 Query: 752 -GIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQ 810 K++E L + ++ E + + + E+S+A + + L + L + + Sbjct: 502 VAAREKLEESHLQRDLLKQEKHELTVALEKAEKSVAALTGAQNKLNSEIADLHTAAAKMS 561 Query: 811 KAYSEYTIQEDELVNRLAVLMDH------DRVVEKQLLEI-EHENKELQKK-NQILLEEN 862 + + EL N+L + ++ D+V E + ++ E E L K+ N+ L E Sbjct: 562 SINEALALDKVEL-NKLVLQLEQENELLSDKVNEMERAKVSEQEKITLYKRTNEELCAEK 620 Query: 863 QNLQISL-------SDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQ 915 +L+ L ++Q L E+ T ++ + Q L++ + + Sbjct: 621 SHLEKLLKKAEEQQEELQMQLRILAEEKEETLEKLNQVYRQQESASSGLEQLRQQSSRQE 680 Query: 916 TLIVQKKKEIEDLEIE---FNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIE 972 + + KE E L E ++ + RD++ L+E+ + LE+ L E + + Sbjct: 681 DAVAKVSKEKEFLVHEKAALEVRLAAVERDRQGLSEQLAEARSVKDTLESSLFEAQQQLS 740 Query: 973 NLNMNVEELN-KMNLELIDKHVQKQQTQSPDY---TEQYINEINKLNAL-----LKQKDE 1023 +L + +L +++ + K V + + + Y TE+ + + + N ++++ Sbjct: 741 HLEITKSQLEIQLHTVVQAKEVIQGEVKCLQYELETERCLMKQEQKNMAQRLIQIEEQHN 800 Query: 1024 EIIALNQKINNAQVSYM--SMVSDYESKLAQFTTKLENMEEEMQRV----SKQLLDSKQH 1077 + L Q + +++ + + S+ E + + +LE E+E K+L K+ Sbjct: 801 NTLKLQQTDHEVEINKLLQDLASEREGRQLELQERLELWEKEKAEAEGQHEKKLFHMKEK 860 Query: 1078 NEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXX 1137 +Q E+ +++ + LT + N K + T +++ + ++ Sbjct: 861 VATMQAQQEEERTRVESANQEILTEKENEKKALLETLLQTQGELTEACHQLEQLRQ---- 916 Query: 1138 XXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQIN 1197 +V+E++E+ E+++ + KL ELQE + KI +E + ++E++ Sbjct: 917 -----EVKEQQEY--EQNITE----KLQAELQETHCKIKMVENM----------HKEEME 955 Query: 1198 QLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQ-READFQKTEHE 1256 +K + L + D+L V EL S + +A ++ I +Q L++ +E QK Sbjct: 956 NIKEEKNILLQQRDDLQKQVEELTSQL-AASEESHQAIGHKAQQELSEAQELSRQKALES 1014 Query: 1257 LRVQLSAFESKYEQLLDSVQSST---QEETNKI-VTMEQVTSL----QNKLQDKEEHLRN 1308 R +LS + E L +++ + Q E +K+ ++Q L + ++Q+ ++ Sbjct: 1015 ERERLSLSLEQKELSLKTLEENNLVQQNEVSKLHSAIQQAQQLHSDHRREIQELNNQVQT 1074 Query: 1309 LQ----EKYADVINQIEILRSEIEDEKVAFX-XXXXXXXXXXXXXXXDLR---TENQSYK 1360 LQ EK A + + + L ++E+ + LR TEN++ Sbjct: 1075 LQEVVLEKEASLAAREKQLLQDLEESRAGERCLRDSLHVLEAEMAELHLRLCSTENRAKA 1134 Query: 1361 QMQE-QSILNIN-EENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQ 1418 E Q N + E +QL K + D A E H L S+ Sbjct: 1135 LATECQQANNAHCEAQSQLDKLHLVLHHVLCDSTDKSRDLVAWSSEQDHVWGLTVSQ--A 1192 Query: 1419 KTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQK 1478 K +T+ + +++RQ L + ++ + D +K +L + K +H+ + Sbjct: 1193 KDLHVELTVDRVAAALQDLRQDLKQTQQDLND-AGKKVQDLELELSKRQAERDHFSAHNQ 1251 Query: 1479 ESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLND 1538 E + + + E + E+ +L K+ L +EVA + E Q+ +++ D Sbjct: 1252 ELQKQLAQSQEVFSGWKAEAAALKKEAI----TLHQEVASLERKLESAEKQKKDVLHERD 1307 Query: 1539 EITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKEL 1580 + ++ + +Q+ V+ AS+T+ +++++ +EL Sbjct: 1308 RLQAVEEKLMWEIKILQESVT-ASETRANTAADMNHSLEQEL 1348 Score = 74.1 bits (174), Expect = 3e-11 Identities = 189/974 (19%), Positives = 408/974 (41%), Gaps = 94/974 (9%) Query: 215 KQQMTKMQENFIAMEAEWKDEKQRLL-----KDIESKDVRISSLEEANKLLEAARFEISL 269 K++ T+ Q+ I E E + E QR + KD+E +D I S +E LE + Sbjct: 1431 KKEKTESQQEQI-QELEKQQELQRTVISKMSKDLEDRDKEIRSQQEEIWELEKQQELQRT 1489 Query: 270 EHSKLAQELEQXXXXXXXXXXXXXXLAKQ-SIEPSCEEKTEIEEKGSLE-IANMTELTKK 327 SK+ ++L L K+ ++ + K + K E I + EL ++ Sbjct: 1490 VVSKMTKDLAHRDQEIQSQQEEIQELEKERELQRTAASKMSKDLKERDEKIRSQQELIEE 1549 Query: 328 IELLEHLN-CQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPW 386 +E + L + + +K LE + + ++ + + K+ ++ R SKM Sbjct: 1550 LEKQQELQRTALSKMSKNLEERDQEIKSQQELIEELKKQ------QELQRTAVSKMNKDL 1603 Query: 387 SQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGK- 445 + E +Q + + + + ++ ++KDL +K+ VI ++ + Sbjct: 1604 EERDQEIRSQQEEIQELEKQRELQRTILSKMSKDLEEKDQVIKFQEGKVMILEQHGTSQV 1663 Query: 446 -------DTLIAQLQLEHQQHME-GPSLIHVGTNTEDVNEIAKVQEQLKQELND-EIKDV 496 D + L+ ++ + M + + E+V + EQL+ L D E + Sbjct: 1664 RSLLVDLDHMKGNLKEKNLELMSLNQQIKELEMEREEVKSLHTSLEQLRAVLRDRENESD 1723 Query: 497 NVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKE 556 + +D + + +E + E+ + M S +L+ QK I +V + + Sbjct: 1724 SQRDQLRLFQQYKEHQEEYLQELQDKVEKMTLSLSKKDQELESQQKQIQEAEEVMEKKLK 1783 Query: 557 IV--RLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDV-YKKMI--EMENLAET 611 V +L + L L +K L+ +K + + + ++ D+ Y K I E + + E+ Sbjct: 1784 TVCDQLEQTLETLKEKERLLDIQKQQTREYEEKTEQMNVLCRDLEYTKAILREKDLMIES 1843 Query: 612 RLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDAL 671 + + I + Q+ D +Q+ ILQ ++++ + L+ C K + + D Sbjct: 1844 QKELIETFQKQEDDSMQQKEILQHLKGALKEQEQETLSLRKQ--CEAFKEKEEKHKTDQT 1901 Query: 672 SASKKELALVIENLKL-DKE--QLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMS 728 +A ++L +L D+E L +++L+ KE ++++ +Q++++ K K + Sbjct: 1902 TAIVQKLQCAESSLAARDQEIASLKEHVQELQKQKESEAKQVKS-LQQDLNKMSKTMKKN 1960 Query: 729 AEKISELLAKIN--H--EEQSKI-----QTQFG-IDAKIQERDLYIENIESELSKYKSRI 778 +I + +IN H EE K+ Q Q ++ +++RD E + +L + + Sbjct: 1961 NLQILKQSEQINVFHICEESRKVALLSCQNQVSLLEEVVRKRDEDNETLLQKLQHQEEEL 2020 Query: 779 CRLEESIAVMEDRRYSLERKADQLGSYLQE-------KQKAYSEYTIQEDELVNRL---- 827 L+ ++ +++ ++R ++ + +E + KA E EDE + L Sbjct: 2021 KTLQNLQLMLSEKKEEIKRHGEE-EKFPEEALHGSEWETKAQGEQKKSEDEEIRGLHEDL 2079 Query: 828 ------------AVLMDHDRV--VEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQ 873 + DRV +EK L + ++L+ + ++ EE + + L + Sbjct: 2080 QYVQQTLTKKDEEIKYQRDRVKYLEKTLAGQKELAQQLEDERKVKGEELKRVIAILKQTE 2139 Query: 874 QHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEH--QTLIVQKKKE-IEDLEI 930 EKA LA S+S LR+ + L+ + E +Q E +++L+ Sbjct: 2140 SGEIEWKEKAQALTLALSKSEMTNGTLREEIAILQSMVSERDKDRFHLQSSPELLKELQS 2199 Query: 931 EFNTQIESA-IRD-----KKVLNEKYEK----NIEYVTQ--LEAQLQEYKNNIENLNMNV 978 Q++ A + D KK LN+ + + ++ ++ + L +L+ + + L Sbjct: 2200 LLLNQVQKASLADIMKEGKKGLNDVHAQGWSPSLTFLEKKLLWQRLECLQQAVARLEHEK 2259 Query: 979 EELNKMNLEL-IDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQK-----I 1032 EL ++N+EL I +++ + + + ++ N L + DE+ + ++K + Sbjct: 2260 SELKQLNVELKITLEQVERERRRLKRSCSHQSQPNANRFSLSESDEDKMPASRKEEARAL 2319 Query: 1033 NNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQH-NEELQILVREQDDQ 1091 + + V+ + +LAQ ++ E + S++LLD Q + L+ ++RE Sbjct: 2320 CSQLAELQNQVTLLQQQLAQERKYKQDYIECCAKTSQELLDLHQELSYSLEAVIREPKAA 2379 Query: 1092 IKELKETKLTFEMN 1105 + E + KL +N Sbjct: 2380 VLEAETQKLDLSLN 2393 Score = 71.3 bits (167), Expect = 2e-10 Identities = 167/813 (20%), Positives = 332/813 (40%), Gaps = 89/813 (10%) Query: 818 IQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYN 877 +Q E N L+ L D E + ++ QK Q L EE Q S+S +Q + Sbjct: 326 VQRPESSNVLSCLSSLD--AEHAFVLVQETLARRQKAIQALKEELSTRQDSISFLQHQHR 383 Query: 878 ALVEKAN----RTDLAESE---STKYQTQLRDLE-------SNLKRITHEHQTLIVQKKK 923 EK R + E E S +Q L+ L NL++I E Q + ++ Sbjct: 384 QQEEKCKKLQQRLEQLEEENKMSNSHQQHLKSLVLALKCDCENLEKIRGELQQKLELSEQ 443 Query: 924 EIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNK 983 E L + NT+++ +++ EK E+ + +E +++ +++L E+ + Sbjct: 444 EASRLR-QSNTELQ--LKEDSAQGEKVEQQLA----MERAHHDHELVLKDLAALEEKHSL 496 Query: 984 MNLELIDKHVQKQQTQ-SPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSM 1042 + EL+ + +++ D +Q E ++L L++ ++ + AL AQ S Sbjct: 497 LQNELVAAREKLEESHLQRDLLKQ---EKHELTVALEKAEKSVAALT----GAQNKLNSE 549 Query: 1043 VSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTF 1102 ++D + A+ ++ E + + ++K +L +Q NE L V E + + K ++ K+T Sbjct: 550 IADLHTAAAKMSSINEALALDKVELNKLVLQLEQENELLSDKVNEME-RAKVSEQEKITL 608 Query: 1103 EMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSA 1162 + E S +E + A + +E+EE +++ + + Q Sbjct: 609 YKRTNE-ELCAEKSHLEKLLKKAEEQQEELQMQLR----ILAEEKEETLEKLNQVYRQQE 663 Query: 1163 KLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRS 1222 ++ L++ + + E +++ + L+ +L + + L +AE RS Sbjct: 664 SASSGLEQLRQQSSRQEDAVAKVSKEKEFLVHEKAALEVRLAAVERDRQGLSEQLAEARS 723 Query: 1223 SISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQE- 1281 + ++ FE +Q L+ E T+ +L +QL E + V+ E Sbjct: 724 -VKDTLESSLFEA----QQQLSHLEI----TKSQLEIQLHTVVQAKEVIQGEVKCLQYEL 774 Query: 1282 ETNK-IVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXX 1340 ET + ++ EQ Q +Q +E+H L+ + D +I L ++ E+ Sbjct: 775 ETERCLMKQEQKNMAQRLIQIEEQHNNTLKLQQTDHEVEINKLLQDLASEREGRQLELQE 834 Query: 1341 XXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEA 1400 E + E+ + ++ E+ A ++ RV A Sbjct: 835 RLELW-------EKEKAEAEGQHEKKLFHMKEKVATMQAQQEEERT-------RVESANQ 880 Query: 1401 KVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESEL- 1459 ++L + E + + + + LT+ + E +RQ++ E ++ +++T + ++EL Sbjct: 881 EILT---EKENEKKALLETLLQTQGELTEACHQLEQLRQEVKEQQEYEQNITEKLQAELQ 937 Query: 1460 -AILRLKMHENANHYETMQKESEIERV---------KLIEELNVKITESVSLNKQVA--- 1506 ++KM EN H E M+ E + + K +EEL ++ S ++ + Sbjct: 938 ETHCKIKMVENM-HKEEMENIKEEKNILLQQRDDLQKQVEELTSQLAASEESHQAIGHKA 996 Query: 1507 --ELNKALEEEVAKTNE-----MQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVS 1559 EL++A E K E + +LE +E+ + TL + QN V S IQ+ Sbjct: 997 QQELSEAQELSRQKALESERERLSLSLEQKELSLKTLEENNLVQQNEVSKLHSAIQQAQQ 1056 Query: 1560 FASDTKQGRDEQLDNTMNKELLDAVPRAELDLA 1592 SD + R+ Q N + L + V E LA Sbjct: 1057 LHSDHR--REIQELNNQVQTLQEVVLEKEASLA 1087 >UniRef50_Q57UD0 Cluster: Kinesin K39, putative; n=1; Trypanosoma brucei|Rep: Kinesin K39, putative - Trypanosoma brucei Length = 1803 Score = 123 bits (297), Expect = 4e-26 Identities = 212/1187 (17%), Positives = 494/1187 (41%), Gaps = 82/1187 (6%) Query: 445 KDTLIAQLQLEHQ-QHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELND---EIKDVNVKD 500 ++ LI +LE Q + + + H + +E A+ +++L +++ EI+ + + Sbjct: 489 EELLIKATELERQVEESKRRAEYHEEMSQRLKDEYAQREQELLEKVRQHRAEIEGIRERK 548 Query: 501 LIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRL 560 E L S+++Q++++ E++ + + + + +Q+ + N + S+ + E+ + Sbjct: 549 DAEML-SSQQQLSRVMSELEQERHSREEALHILRERQEQLSAALCNSQQSSEKHTELQQQ 607 Query: 561 TEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKM-IEMENLAETRLKAIS-L 618 EEL H QK+ E E + + L + R ++ + + +++E +K I+ L Sbjct: 608 NEELSHRMQKLLEECEAQQRILSDLEVFRLERNELEEIAQFLDLKLEETEHRHIKTINHL 667 Query: 619 LESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKEL 678 L + + + +L EVE +L +Q DQ + K+ H Q++ +KK L Sbjct: 668 LTTIGMHNLWQAELLTAVGTEVETQLTKCNQHHFDQRAAMEKN-HKLFQMEQHQMTKK-L 725 Query: 679 ALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEK--ISELL 736 I L+ + E+ + + + I NK + + LE + AE+ + + L Sbjct: 726 EQKILMLEKEIEEAKKQLDTTKQSEAAITNKARQAEDARAAVERNLETVEAERDELQQRL 785 Query: 737 AKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICR----LEESIAVMEDRR 792 +++ +S+++ A + ER+L E +E+E ++ + R+ L+ + ED R Sbjct: 786 DATSNDLKSQLRNSEDARAAV-ERNL--ETVEAERNELQQRLDATSNDLKSQLRNSEDAR 842 Query: 793 YSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQ 852 ++ER + + + E+ + ++L ++L D VE+ L +E E ELQ Sbjct: 843 AAVERNLETVEA---ERNELQQRLDATSNDLKSQLRNSEDARAAVERNLETVEAERNELQ 899 Query: 853 KK----NQILLEENQNLQISLSDMQQHYNAL-VEKANRTDLAESESTKYQTQLRDLESNL 907 ++ + L + +N + + + ++++ + E+ ++ S ++QLR+ E Sbjct: 900 QRLDATSNDLKSQLRNSEDARAAVERNLETVEAERNELQQRLDATSNDLKSQLRNSEDAR 959 Query: 908 KRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYV----TQLEAQ 963 + +T+ ++ + + L+ N ++S +R+ + E+N+E V +L+ + Sbjct: 960 AAVERNLETVEAERNELQQRLDATSN-DLKSQLRNSEDARAAVERNLETVEAERNELQQR 1018 Query: 964 LQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDE 1023 L N++++ N E+ ++++++ + + + ++ N L + L+ ++ Sbjct: 1019 LDATSNDLKSQLRNSEDAR----AAVERNLETVEAERNELQQRLDATSNDLKSQLRNSED 1074 Query: 1024 EIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQ- 1082 A+ + + + + ++ ++L N E+ V + L + ELQ Sbjct: 1075 ARAAVERNLETVEAERNELQQRLDATSNDLKSQLRNSEDARAAVERNLETVEAERNELQQ 1134 Query: 1083 ---ILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXX 1139 + Q++ ++ + E N+ E + ++ D +N D Sbjct: 1135 RLDATSNDLKSQLRNSEDARAAVERNLETVEAE--RNELQQRLDATSN-DLKSQLRNSED 1191 Query: 1140 XXLKVQEEEEFIQ-ERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQ 1198 V+ E ++ ER+ LQ+ +L+ + +++ E + + + + N+ Sbjct: 1192 ARAAVERNLETVEAERNELQQ---RLDATSNDLKSQLRNSEDARAAVERNLETVEAERNE 1248 Query: 1199 LKSKLEQLNTENDNLLSTVAELRSSISS-AVDQRGFEIAELWKQHLAQREADFQKTEHEL 1257 L+ +L+ T ND ++LR+S + A +R E E + L QR T ++L Sbjct: 1249 LQQRLDA--TSND----LKSQLRNSEDARAAVERNLETVEAERNELQQR---LDATSNDL 1299 Query: 1258 RVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVI 1317 + QL E + +++ + + E N++ TS D + LRN ++ A V Sbjct: 1300 KSQLRNSEDARAAVERNLE-TVEAERNELQQRLDATS-----NDLKSQLRNSEDARAAVE 1353 Query: 1318 NQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQL 1377 +E + +E + LR ++ + E+++ + E +L Sbjct: 1354 RNLETVEAERNE-------LQQRLDATSNDLKSQLR-NSEDARAAVERNLETVEAERNEL 1405 Query: 1378 KKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENV 1437 ++ DA A V +E + +E+ Q+ T + N Sbjct: 1406 QQRLDATSNDLKSQLRNSEDARAAVERNLETVEAERNELQQR---LDATSNDLKSQLRNS 1462 Query: 1438 RQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITE 1497 E+ +E + E+E L+ ++ +N ++ + SE R + L E Sbjct: 1463 EDARAAVERNLETV----EAERNELQQRLDATSNDLKSQLRNSEDARAAVERNLETVEAE 1518 Query: 1498 SVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKH 1557 L +++ + L+ ++ + + + A+E + T+ E LQ + A+S+ ++ Sbjct: 1519 RNELQQRLDATSNDLKSQLRNSEDARAAVER---NLETVEAERNELQQRLDATSNDLKSQ 1575 Query: 1558 VSFASDTKQGRDEQLD--NTMNKELLDAVPRAELDLAMYMLHQRDVR 1602 + + D + + L+ EL + DL + + D R Sbjct: 1576 LRNSEDARAAVERNLETVEAERNELQQRLDATSNDLKSQLRNSEDAR 1622 Score = 98.7 bits (235), Expect = 1e-18 Identities = 183/1115 (16%), Positives = 467/1115 (41%), Gaps = 85/1115 (7%) Query: 234 DEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXX 293 + +QR+L D+E + + LEE + L+ E H K L Sbjct: 623 EAQQRILSDLEVFRLERNELEEIAQFLDLKLEETEHRHIKTINHLLTTIGMHNLWQAELL 682 Query: 294 XLAKQSIEPSCEE--KTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLAT 351 +E + + +++ ++E + ++ ++ + L +I KE+E Sbjct: 683 TAVGTEVETQLTKCNQHHFDQRAAMEKNHKLFQMEQHQMTKKLEQKILMLEKEIEEAKKQ 742 Query: 352 MGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKIN--KNEIAK 409 + T ++ ++ + K + A + + + L Q D N K+++ Sbjct: 743 LDTTKQSEAAITNKA----RQAEDARAAVERNLETVEAERDELQQRLDATSNDLKSQLRN 798 Query: 410 LEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVG 469 E ++ ++L E V +E++ + QL + + ++ Sbjct: 799 SEDARAAVERNL---ETVEAERNELQQRLDATSND-----LKSQLRNSEDARAAVERNLE 850 Query: 470 TNTEDVNEIAKVQEQLKQELNDEIKD-VNVKDLIEK-LKSAEEQITQLNDEIDAANKNMI 527 T + NE+ + + +L ++++ + + +E+ L++ E + +L +DA + ++ Sbjct: 851 TVEAERNELQQRLDATSNDLKSQLRNSEDARAAVERNLETVEAERNELQQRLDATSNDLK 910 Query: 528 KVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVD 587 N + +++ ++ ++ N+ RL + L ++ E+ + ++ +L Sbjct: 911 SQLRNSEDARAAVERNLETVE--AERNELQQRLDATSNDLKSQLRNSEDARAAVERNLET 968 Query: 588 YDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKL-AD 646 ++ R +++ +++ N +++L+ E + + + L ++ + +E++ +L A Sbjct: 969 VEAER---NELQQRLDATSNDLKSQLRN---SEDARAAVERNLETVEAERNELQQRLDAT 1022 Query: 647 ISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDI 706 + L+S SE +E ++ + A + EL + L L +++ E+ + + Sbjct: 1023 SNDLKSQLRNSEDARAAVERNLETVEAERNELQ---QRLDATSNDLKSQLRNSEDARAAV 1079 Query: 707 MNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIEN 766 L+ E +L +L+ S ++L +++ + E ++ + ++ ER+ + Sbjct: 1080 ERNLETVEAERNELQQRLDATS----NDLKSQLRNSEDARAAVERNLETVEAERNELQQR 1135 Query: 767 IESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNR 826 +++ + KS++ E++ A +E ++E + ++ LQ++ A S ++L ++ Sbjct: 1136 LDATSNDLKSQLRNSEDARAAVERNLETVEAERNE----LQQRLDATS------NDLKSQ 1185 Query: 827 LAVLMDHDRVVEKQLLEIEHENKELQKK----NQILLEENQNLQISLSDMQQHYNAL-VE 881 L D VE+ L +E E ELQ++ + L + +N + + + ++++ + E Sbjct: 1186 LRNSEDARAAVERNLETVEAERNELQQRLDATSNDLKSQLRNSEDARAAVERNLETVEAE 1245 Query: 882 KANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIR 941 + ++ S ++QLR+ E + +T+ ++ + + L+ N ++S +R Sbjct: 1246 RNELQQRLDATSNDLKSQLRNSEDARAAVERNLETVEAERNELQQRLDATSN-DLKSQLR 1304 Query: 942 DKKVLNEKYEKNIEYV----TQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQ 997 + + E+N+E V +L+ +L N++++ N E+ ++++++ + Sbjct: 1305 NSEDARAAVERNLETVEAERNELQQRLDATSNDLKSQLRNSEDAR----AAVERNLETVE 1360 Query: 998 TQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKL 1057 + + ++ N L + L+ ++ A+ + + + + ++ ++L Sbjct: 1361 AERNELQQRLDATSNDLKSQLRNSEDARAAVERNLETVEAERNELQQRLDATSNDLKSQL 1420 Query: 1058 ENMEEEMQRVSKQLLDSKQHNEELQ----ILVREQDDQIKELKETKLTFEMNIPKTEGMI 1113 N E+ V + L + ELQ + Q++ ++ + E N+ E Sbjct: 1421 RNSEDARAAVERNLETVEAERNELQQRLDATSNDLKSQLRNSEDARAAVERNLETVEAE- 1479 Query: 1114 ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQ-ERSVLQEQSAKLNTELQECY 1172 + ++ D +N D V+ E ++ ER+ LQ+ +L+ + Sbjct: 1480 -RNELQQRLDATSN-DLKSQLRNSEDARAAVERNLETVEAERNELQQ---RLDATSNDLK 1534 Query: 1173 TKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISS-AVDQR 1231 +++ E + + + + N+L+ +L+ T ND ++LR+S + A +R Sbjct: 1535 SQLRNSEDARAAVERNLETVEAERNELQQRLDA--TSND----LKSQLRNSEDARAAVER 1588 Query: 1232 GFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQ 1291 E E + L QR T ++L+ QL E + +++ + + E N++ Sbjct: 1589 NLETVEAERNELQQR---LDATSNDLKSQLRNSEDARAAVERNLE-TVEAERNELQQRLD 1644 Query: 1292 VTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSE 1326 TS D + LRN ++ A V +E + +E Sbjct: 1645 ATS-----NDLKSQLRNSEDARAAVERNLETVEAE 1674 Score = 97.5 bits (232), Expect = 3e-18 Identities = 188/1149 (16%), Positives = 481/1149 (41%), Gaps = 85/1149 (7%) Query: 145 THLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXX 204 T L+ + + + ++ K+ + + +K+ +K ++E + + Sbjct: 691 TQLTKCNQHHFDQRAAMEKNHKLFQMEQHQMTKKLEQKILMLEKEIEEAKKQLDTTKQSE 750 Query: 205 XXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVR--ISSLEEANKLLEA 262 + ++ N +EAE + +QRL D S D++ + + E+A +E Sbjct: 751 AAITNKARQAEDARAAVERNLETVEAERDELQQRL--DATSNDLKSQLRNSEDARAAVER 808 Query: 263 ARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCE----EKTEIEEKGSLEI 318 + E ++L Q L+ A+ ++E + E E+ E++++ L+ Sbjct: 809 NLETVEAERNELQQRLDATSNDLKSQLRNSED-ARAAVERNLETVEAERNELQQR--LD- 864 Query: 319 ANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNT 378 A +L ++ E + + + +E + + A S+ K S L + + R Sbjct: 865 ATSNDLKSQLRNSEDARAAVERNLETVEAERNELQQRLDATSNDLK--SQLRNSEDAR-A 921 Query: 379 ASKMKSPWSQLSSETLNQDTDKKIN--KNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXX 436 A + + L Q D N K+++ E ++ ++L E V +E++ Sbjct: 922 AVERNLETVEAERNELQQRLDATSNDLKSQLRNSEDARAAVERNL---ETVEAERNELQQ 978 Query: 437 XXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKD- 495 + QL + + ++ T + NE+ + + +L ++++ Sbjct: 979 RLDATSND-----LKSQLRNSEDARAAVERNLETVEAERNELQQRLDATSNDLKSQLRNS 1033 Query: 496 VNVKDLIEK-LKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSN 554 + + +E+ L++ E + +L +DA + ++ N + +++ ++ ++ N Sbjct: 1034 EDARAAVERNLETVEAERNELQQRLDATSNDLKSQLRNSEDARAAVERNLETVE--AERN 1091 Query: 555 KEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLK 614 + RL + L ++ E+ + ++ +L ++ R +++ +++ N +++L+ Sbjct: 1092 ELQQRLDATSNDLKSQLRNSEDARAAVERNLETVEAER---NELQQRLDATSNDLKSQLR 1148 Query: 615 AISLLESQKFDLVQELHILQQKYDEVEDKL-ADISQLQSDQVCSEIKSVHLEEQIDALSA 673 E + + + L ++ + +E++ +L A + L+S SE +E ++ + A Sbjct: 1149 N---SEDARAAVERNLETVEAERNELQQRLDATSNDLKSQLRNSEDARAAVERNLETVEA 1205 Query: 674 SKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKIS 733 + EL + L L +++ E+ + + L+ E +L +L+ S + Sbjct: 1206 ERNELQ---QRLDATSNDLKSQLRNSEDARAAVERNLETVEAERNELQQRLDATS----N 1258 Query: 734 ELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRY 793 +L +++ + E ++ + ++ ER+ + +++ + KS++ E++ A +E Sbjct: 1259 DLKSQLRNSEDARAAVERNLETVEAERNELQQRLDATSNDLKSQLRNSEDARAAVERNLE 1318 Query: 794 SLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQK 853 ++E + ++ LQ++ A S ++L ++L D VE+ L +E E ELQ+ Sbjct: 1319 TVEAERNE----LQQRLDATS------NDLKSQLRNSEDARAAVERNLETVEAERNELQQ 1368 Query: 854 K----NQILLEENQNLQISLSDMQQHYNAL-VEKANRTDLAESESTKYQTQLRDLESNLK 908 + + L + +N + + + ++++ + E+ ++ S ++QLR+ E Sbjct: 1369 RLDATSNDLKSQLRNSEDARAAVERNLETVEAERNELQQRLDATSNDLKSQLRNSEDARA 1428 Query: 909 RITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYV----TQLEAQL 964 + +T+ ++ + + L+ N ++S +R+ + E+N+E V +L+ +L Sbjct: 1429 AVERNLETVEAERNELQQRLDATSN-DLKSQLRNSEDARAAVERNLETVEAERNELQQRL 1487 Query: 965 QEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEE 1024 N++++ N E+ ++++++ + + + ++ N L + L+ ++ Sbjct: 1488 DATSNDLKSQLRNSEDAR----AAVERNLETVEAERNELQQRLDATSNDLKSQLRNSEDA 1543 Query: 1025 IIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQ-- 1082 A+ + + + + ++ ++L N E+ V + L + ELQ Sbjct: 1544 RAAVERNLETVEAERNELQQRLDATSNDLKSQLRNSEDARAAVERNLETVEAERNELQQR 1603 Query: 1083 --ILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXX 1140 + Q++ ++ + E N+ E + ++ D +N D Sbjct: 1604 LDATSNDLKSQLRNSEDARAAVERNLETVEAE--RNELQQRLDATSN-DLKSQLRNSEDA 1660 Query: 1141 XLKVQEEEEFIQ-ERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQL 1199 V+ E ++ ER+ LQ+ +L+ + +++ E + + + + N+L Sbjct: 1661 RAAVERNLETVEAERNELQQ---RLDATSNDLKSQLRNSEDARAAVERNLETVEAERNEL 1717 Query: 1200 KSKLEQLNTENDNLLSTVAELRSSISS-AVDQRGFEIAELWKQHLAQREADFQKTEHELR 1258 + +L+ T ND ++LR+S + A +R E E + L QR F++ L Sbjct: 1718 QQRLDA--TSND----LKSQLRNSEDARAAVERNLETVEAERNELQQRLDVFERECAVLN 1771 Query: 1259 VQLSAFESK 1267 ++LS K Sbjct: 1772 IRLSYLRRK 1780 Score = 91.9 bits (218), Expect = 1e-16 Identities = 190/1020 (18%), Positives = 429/1020 (42%), Gaps = 81/1020 (7%) Query: 221 MQENFIAMEAEWKDEKQRLLKDIESKDVR--ISSLEEANKLLEAARFEISLEHSKLAQEL 278 ++ N +EAE + +QRL D S D++ + + E+A +E + E ++L Q L Sbjct: 806 VERNLETVEAERNELQQRL--DATSNDLKSQLRNSEDARAAVERNLETVEAERNELQQRL 863 Query: 279 EQXXXXXXXXXXXXXXLAKQSIEPSCE----EKTEIEEK---GSLEIANMTELTKKIELL 331 + A+ ++E + E E+ E++++ S ++ + ++ Sbjct: 864 DATSNDLKSQLRNSED-ARAAVERNLETVEAERNELQQRLDATSNDLKSQLRNSEDARAA 922 Query: 332 EHLNCQ-IRQTNKELENKLATMGTESKAVSSPSKKGSPLISR-----KSGRN-TASKMKS 384 N + + EL+ +L + K+ S+ + R ++ RN ++ + Sbjct: 923 VERNLETVEAERNELQQRLDATSNDLKSQLRNSEDARAAVERNLETVEAERNELQQRLDA 982 Query: 385 PWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDL-VDKEYVISEKDTXXXXXXXXXX 443 + L S+ N + + + + +E L + L + S+ Sbjct: 983 TSNDLKSQLRNSEDARAAVERNLETVEAERNELQQRLDATSNDLKSQLRNSEDARAAVER 1042 Query: 444 GKDTLIAQLQLEHQQHMEGPS--LIHVGTNTEDVN-EIAKVQEQLKQELND--EIKDVNV 498 +T+ A+ + E QQ ++ S L N+ED + + E ++ E N+ + D Sbjct: 1043 NLETVEAE-RNELQQRLDATSNDLKSQLRNSEDARAAVERNLETVEAERNELQQRLDATS 1101 Query: 499 KDLIEKLKSAEE--QITQLNDEIDAANKNMIKVKSNHKLK-LKQMQKTIDNFSKVSDSNK 555 DL +L+++E+ + N E A +N ++ + + LK + ++ + N Sbjct: 1102 NDLKSQLRNSEDARAAVERNLETVEAERNELQQRLDATSNDLKSQLRNSEDARAAVERNL 1161 Query: 556 EIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKA 615 E V E + L Q+ L+ +L+ L + + R + + N + RL A Sbjct: 1162 ETVE--AERNELQQR---LDATSNDLKSQLRNSEDARAAVERNLETVEAERNELQQRLDA 1216 Query: 616 ISL-LESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSAS 674 S L+SQ + +++ + VE + ++ Q + D +++KS L DA +A Sbjct: 1217 TSNDLKSQLRNSEDARAAVERNLETVEAERNELQQ-RLDATSNDLKS-QLRNSEDARAAV 1274 Query: 675 KKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISE 734 ++ L E ++ ++ +L + L+ D+ ++L+N + LE + AE+ +E Sbjct: 1275 ERNL----ETVEAERNELQ---QRLDATSNDLKSQLRNSEDARAAVERNLETVEAER-NE 1326 Query: 735 LLAKINHEEQS-KIQTQFGIDAKIQ-ERDLYIENIESELSKYKSRICR----LEESIAVM 788 L +++ K Q + DA+ ER+L E +E+E ++ + R+ L+ + Sbjct: 1327 LQQRLDATSNDLKSQLRNSEDARAAVERNL--ETVEAERNELQQRLDATSNDLKSQLRNS 1384 Query: 789 EDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHEN 848 ED R ++ER + + + E+ + ++L ++L D VE+ L +E E Sbjct: 1385 EDARAAVERNLETVEA---ERNELQQRLDATSNDLKSQLRNSEDARAAVERNLETVEAER 1441 Query: 849 KELQKK----NQILLEENQNLQISLSDMQQHYNAL-VEKANRTDLAESESTKYQTQLRDL 903 ELQ++ + L + +N + + + ++++ + E+ ++ S ++QLR+ Sbjct: 1442 NELQQRLDATSNDLKSQLRNSEDARAAVERNLETVEAERNELQQRLDATSNDLKSQLRNS 1501 Query: 904 ESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYV----TQ 959 E + +T+ ++ + + L+ N ++S +R+ + E+N+E V + Sbjct: 1502 EDARAAVERNLETVEAERNELQQRLDATSN-DLKSQLRNSEDARAAVERNLETVEAERNE 1560 Query: 960 LEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLK 1019 L+ +L N++++ N E+ ++++++ + + + ++ N L + L+ Sbjct: 1561 LQQRLDATSNDLKSQLRNSEDAR----AAVERNLETVEAERNELQQRLDATSNDLKSQLR 1616 Query: 1020 QKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNE 1079 ++ A+ + + + + ++ ++L N E+ V + L + Sbjct: 1617 NSEDARAAVERNLETVEAERNELQQRLDATSNDLKSQLRNSEDARAAVERNLETVEAERN 1676 Query: 1080 ELQ----ILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXX 1135 ELQ + Q++ ++ + E N+ E + ++ D +N D Sbjct: 1677 ELQQRLDATSNDLKSQLRNSEDARAAVERNLETVEAE--RNELQQRLDATSN-DLKSQLR 1733 Query: 1136 XXXXXXLKVQEEEEFIQ-ERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQE 1194 V+ E ++ ER+ LQ+ +L+ +EC I+L L +L VV +E Sbjct: 1734 NSEDARAAVERNLETVEAERNELQQ---RLDVFERECAVLNIRLSYLRRKLLSGFVVGEE 1790 Score = 83.0 bits (196), Expect = 6e-14 Identities = 194/1042 (18%), Positives = 411/1042 (39%), Gaps = 87/1042 (8%) Query: 590 SGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQ 649 SG++I + + + +LA + A S + Q+F+ + +++ V D LAD+++ Sbjct: 288 SGQVITTAGMSSRMNLVDLAGSERVAQSEVVGQQFNEARYINLSLTTLGRVIDMLADMAK 347 Query: 650 LQSDQVCS----EIKSVHLEEQIDALSASKKELAL-VIENLKLDKEQLYGTIKDLENDKE 704 +S Q + E K ++ + D+L + K + + L+ E+ T++ + Sbjct: 348 NKSSQWSTPPYRESKLTYILK--DSLGGNSKTFMIATVSPSALNYEETLSTLR-YASRAR 404 Query: 705 DIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYI 764 DI+N + +LE+ + ++ K + + ++A+ Q+R + Sbjct: 405 DIVNMTRVNEDPRARRIRELEEQMEQMRQDIKGKDPTYVRELEEKLVLLEAEAQKRAADL 464 Query: 765 ENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQE-KQKA-YSEYTIQ--E 820 +E E K I R E+ + E R L KA +L ++E K++A Y E Q + Sbjct: 465 HALEKEREK---NIIR-EKMLYATEVEREELLIKATELERQVEESKRRAEYHEEMSQRLK 520 Query: 821 DELVNRLAVLMDHDRVVEKQLLEI-EHENKELQKKNQILLEENQNLQISLSDMQQHYNAL 879 DE R L++ R ++ I E ++ E+ Q L L+ ++ + L Sbjct: 521 DEYAQREQELLEKVRQHRAEIEGIRERKDAEMLSSQQQLSRVMSELEQERHSREEALHIL 580 Query: 880 VEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQ---KKKEIEDLEI---EFN 933 E+ + A S + + +L+ + ++H Q L+ + +++ + DLE+ E N Sbjct: 581 RERQEQLSAALCNSQQSSEKHTELQQQNEELSHRMQKLLEECEAQQRILSDLEVFRLERN 640 Query: 934 TQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYK----NNIENLNMNVE-ELNKMNLEL 988 E A L E ++I+ + L + + + + VE +L K N Sbjct: 641 ELEEIAQFLDLKLEETEHRHIKTINHLLTTIGMHNLWQAELLTAVGTEVETQLTKCNQHH 700 Query: 989 IDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYES 1048 D+ ++ EQ+ + K+ +++I+ L ++I A+ + + Sbjct: 701 FDQRAAMEKNHKLFQMEQH--------QMTKKLEQKILMLEKEIEEAK----KQLDTTKQ 748 Query: 1049 KLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQ----ILVREQDDQIKELKETKLTFEM 1104 A T K E+ V + L + +ELQ + Q++ ++ + E Sbjct: 749 SEAAITNKARQAEDARAAVERNLETVEAERDELQQRLDATSNDLKSQLRNSEDARAAVER 808 Query: 1105 NIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQ-ERSVLQEQSAK 1163 N+ E + ++ D +N D V+ E ++ ER+ LQ+ + Sbjct: 809 NLETVEAE--RNELQQRLDATSN-DLKSQLRNSEDARAAVERNLETVEAERNELQQ---R 862 Query: 1164 LNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSS 1223 L+ + +++ E + + + + N+L+ +L+ T ND ++LR+S Sbjct: 863 LDATSNDLKSQLRNSEDARAAVERNLETVEAERNELQQRLDA--TSND----LKSQLRNS 916 Query: 1224 ISS-AVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEE 1282 + A +R E E + L QR T ++L+ QL E + +++ + + E Sbjct: 917 EDARAAVERNLETVEAERNELQQR---LDATSNDLKSQLRNSEDARAAVERNLE-TVEAE 972 Query: 1283 TNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXX 1342 N++ TS D + LRN ++ A V +E + +E + Sbjct: 973 RNELQQRLDATS-----NDLKSQLRNSEDARAAVERNLETVEAERNE-------LQQRLD 1020 Query: 1343 XXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKV 1402 LR ++ + E+++ + E +L++ DA A V Sbjct: 1021 ATSNDLKSQLR-NSEDARAAVERNLETVEAERNELQQRLDATSNDLKSQLRNSEDARAAV 1079 Query: 1403 LELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAIL 1462 +E + +E+ Q+ T + N E+ +E + E+E L Sbjct: 1080 ERNLETVEAERNELQQR---LDATSNDLKSQLRNSEDARAAVERNLETV----EAERNEL 1132 Query: 1463 RLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEM 1522 + ++ +N ++ + SE R + L E L +++ + L+ ++ + + Sbjct: 1133 QQRLDATSNDLKSQLRNSEDARAAVERNLETVEAERNELQQRLDATSNDLKSQLRNSEDA 1192 Query: 1523 QTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLD--NTMNKEL 1580 + A+E + T+ E LQ + A+S+ ++ + + D + + L+ EL Sbjct: 1193 RAAVER---NLETVEAERNELQQRLDATSNDLKSQLRNSEDARAAVERNLETVEAERNEL 1249 Query: 1581 LDAVPRAELDLAMYMLHQRDVR 1602 + DL + + D R Sbjct: 1250 QQRLDATSNDLKSQLRNSEDAR 1271 Score = 82.2 bits (194), Expect = 1e-13 Identities = 167/954 (17%), Positives = 380/954 (39%), Gaps = 75/954 (7%) Query: 676 KELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAE-KISE 734 +EL + L+ + ++ + LE ++E +N I+E M ++E+ K +E Sbjct: 444 RELEEKLVLLEAEAQKRAADLHALEKERE------KNIIREKMLYATEVEREELLIKATE 497 Query: 735 LLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYS 794 L ++ E+SK + ++ + + +D Y + + L K + +E + S Sbjct: 498 LERQV---EESKRRAEYHEEMSQRLKDEYAQREQELLEKVRQHRAEIEGIRERKDAEMLS 554 Query: 795 LERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKK 854 +++ ++ S L++++ + E E +L+ + + + ++ E++ +N+EL + Sbjct: 555 SQQQLSRVMSELEQERHSREEALHILRERQEQLSAALCNSQQSSEKHTELQQQNEELSHR 614 Query: 855 NQILLEENQNLQISLSDMQ---QHYNALVEKANRTDL-AESESTKYQTQLRDLESNLKRI 910 Q LLEE + Q LSD++ N L E A DL E ++ + L + + Sbjct: 615 MQKLLEECEAQQRILSDLEVFRLERNELEEIAQFLDLKLEETEHRHIKTINHLLTTIGMH 674 Query: 911 THEHQTLIVQKKKEIEDLEIEFN----TQIESAIRDKKVLN-EKYE--KNIEY-VTQLEA 962 L+ E+E + N Q + ++ K+ E+++ K +E + LE Sbjct: 675 NLWQAELLTAVGTEVETQLTKCNQHHFDQRAAMEKNHKLFQMEQHQMTKKLEQKILMLEK 734 Query: 963 QLQEYKNNIENLNMNVEEL-NKMN-----LELIDKHVQKQQTQSPDYTEQYINEINKLNA 1016 +++E K ++ + + NK ++++++ + + + ++ N L + Sbjct: 735 EIEEAKKQLDTTKQSEAAITNKARQAEDARAAVERNLETVEAERDELQQRLDATSNDLKS 794 Query: 1017 LLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQ 1076 L+ ++ A+ + + + + ++ ++L N E+ V + L + Sbjct: 795 QLRNSEDARAAVERNLETVEAERNELQQRLDATSNDLKSQLRNSEDARAAVERNLETVEA 854 Query: 1077 HNEELQ----ILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXX 1132 ELQ + Q++ ++ + E N+ E + ++ D +N D Sbjct: 855 ERNELQQRLDATSNDLKSQLRNSEDARAAVERNLETVEAE--RNELQQRLDATSN-DLKS 911 Query: 1133 XXXXXXXXXLKVQEEEEFIQ-ERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVV 1191 V+ E ++ ER+ LQ+ +L+ + +++ E + + Sbjct: 912 QLRNSEDARAAVERNLETVEAERNELQQ---RLDATSNDLKSQLRNSEDARAAVERNLET 968 Query: 1192 NQEQINQLKSKLEQLNTENDNLLSTVAELRSSISS-AVDQRGFEIAELWKQHLAQREADF 1250 + + N+L+ +L+ T ND ++LR+S + A +R E E + L QR Sbjct: 969 VEAERNELQQRLDA--TSND----LKSQLRNSEDARAAVERNLETVEAERNELQQR---L 1019 Query: 1251 QKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQ 1310 T ++L+ QL E + +++ + + E N++ TS D + LRN + Sbjct: 1020 DATSNDLKSQLRNSEDARAAVERNLE-TVEAERNELQQRLDATS-----NDLKSQLRNSE 1073 Query: 1311 EKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNI 1370 + A V +E + +E + LR ++ + E+++ + Sbjct: 1074 DARAAVERNLETVEAERNE-------LQQRLDATSNDLKSQLR-NSEDARAAVERNLETV 1125 Query: 1371 NEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQR 1430 E +L++ DA A V +E + +E+ Q+ T Sbjct: 1126 EAERNELQQRLDATSNDLKSQLRNSEDARAAVERNLETVEAERNELQQR---LDATSNDL 1182 Query: 1431 NDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEE 1490 + N E+ +E + E+E L+ ++ +N ++ + SE R + Sbjct: 1183 KSQLRNSEDARAAVERNLETV----EAERNELQQRLDATSNDLKSQLRNSEDARAAVERN 1238 Query: 1491 LNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRAS 1550 L E L +++ + L+ ++ + + + A+E + T+ E LQ + A+ Sbjct: 1239 LETVEAERNELQQRLDATSNDLKSQLRNSEDARAAVER---NLETVEAERNELQQRLDAT 1295 Query: 1551 SSKIQKHVSFASDTKQGRDEQLD--NTMNKELLDAVPRAELDLAMYMLHQRDVR 1602 S+ ++ + + D + + L+ EL + DL + + D R Sbjct: 1296 SNDLKSQLRNSEDARAAVERNLETVEAERNELQQRLDATSNDLKSQLRNSEDAR 1349 >UniRef50_Q4E572 Cluster: Antigenic protein, putative; n=2; Trypanosoma cruzi|Rep: Antigenic protein, putative - Trypanosoma cruzi Length = 2517 Score = 123 bits (297), Expect = 4e-26 Identities = 207/1069 (19%), Positives = 477/1069 (44%), Gaps = 74/1069 (6%) Query: 295 LAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGT 354 L + S++ + E+T E + + +L + +E L++ + + + ++ T Sbjct: 699 LLQASLDEATSERTFAENR-------IADLQRTVENLQNQLNVLENAETDYKTEMYKQTT 751 Query: 355 ESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVI 414 + + + + +K SP S R K+ + S+ T + E LE Sbjct: 752 KKEPLEARAKNDSP--SEDFLRTQIGKLNPVEKETSAAKQLTGTKNQEKAGEQYDLEKPN 809 Query: 415 QSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTED 474 K YV + T + A+ QL+ + +E S G ++ Sbjct: 810 TPYINYKTTKNYVFTSSGTKQEKSTSRTKNI-SCTAEPQLKQNKKVEDTSAFKKGREEDN 868 Query: 475 VNEIAKVQEQL-----KQELNDEIKDVNVKDL-IEKLKSAEEQITQLNDEIDAANKNMIK 528 V + Q+ L KQ+ +E++ K+ I+K ++ ++ + + ++N K Sbjct: 869 VKKSDNKQQSLQEMFVKQQEEEELQQFQQKNKHIQKTENEQQHVKSKIIPTTSKSENQ-K 927 Query: 529 VKSNHKLKLKQMQKTIDNFS---KVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHL 585 K+ + KL+++ K + S ++++ K+ +++ ++ E ++ + + H Sbjct: 928 EKAIPQNKLQKVIKKTEKHSITRQITEETKQNTIPIKKVPAQNKDFHENTKQNSDERKHT 987 Query: 586 VDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLA 645 + +G +++ + ++ E +L A L+ Q L +L ++ E+KL Sbjct: 988 MKTMAGLQRQNEELQSQLKESRRGEEKLDA---LQRQNEQLQSQL----KESCRGEEKL- 1039 Query: 646 DISQLQSDQVCSEIK-SVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKE 704 D Q Q++++ S++K S EE++DAL +EL ++ + +E+L L+ E Sbjct: 1040 DALQRQNEELQSQLKESRRGEEKLDALQRQNEELQSQLKESRRGEEKLDA----LQRQNE 1095 Query: 705 DIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQ-SKIQTQFG-IDAKIQERDL 762 + ++L+ + + D L++ + + S+L EE+ +Q Q + ++++E Sbjct: 1096 QLQSQLKES-RRGEEKLDALQRQNEQLQSQLRESRRGEEKLDALQRQNEELQSQLKESRR 1154 Query: 763 YIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTI---Q 819 E +++ + + +L+ES E++ +L+R+ +QL S L+E ++ + Q Sbjct: 1155 GEEKLDALQRQNEQLQSQLKESRRG-EEKLDALQRQNEQLQSQLKESRRGEEKLDALQRQ 1213 Query: 820 EDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNAL 879 +EL ++L R E++L ++ +N+ELQ + L+E++ + L +Q+ L Sbjct: 1214 NEELQSQLK----ESRRGEEKLDALQRQNEELQSQ----LKESRRGEEKLDALQRQNEEL 1265 Query: 880 VEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTL-IVQKKKEIEDLEIEFNTQIES 938 + + E + Q Q L+S LK + L +Q++ E +++ + + E Sbjct: 1266 QSQLKESRRGEEKLDALQRQNEQLQSQLKESRRGEEKLDALQRQNEELQSQLKESRRGEE 1325 Query: 939 AIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNK--MNLELIDKHVQKQ 996 + + NE+ + ++ + E +L + E L ++E + L+ + + ++ Sbjct: 1326 KLDALQRQNEELQSQLKESRRGEEKLDALQRQNEELQSQLKESRRGEEKLDALQRQNEEL 1385 Query: 997 QTQSPDYT--EQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDY-ESKLAQF 1053 Q+Q + E+ ++ + + N L+ + +E +K++ Q + S ES+ + Sbjct: 1386 QSQLKESRRGEEKLDALQRQNEQLQSQLKESRRGEEKLDALQRQNEELQSQLKESRRGE- 1444 Query: 1054 TTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFE-MNIPKTEGM 1112 KL+ ++ + +++ QL +S++ E+L L R+ + +LKE++ E ++ + + Sbjct: 1445 -EKLDALQRQNEQLQSQLKESRRGEEKLDALQRQNEQLQSQLKESRRGEEKLDALQRQNE 1503 Query: 1113 IISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECY 1172 + S ++ +D LK E ++ LQ Q+ +L ++L+E Sbjct: 1504 ELQSQLKESRRGEEKLDALQRQNEELRSQLKESRRGE--EKLDALQRQNEQLQSQLKESR 1561 Query: 1173 TKIIQLETLNTELTGHDVVNQ-EQINQLKSKLEQLNTENDNLLSTVAELRSSISS--AVD 1229 +L+ L + + +Q ++ + + KL+ L +N+ L S + E R A+ Sbjct: 1562 RGEEKLDALQRQ--NEQLQSQLKESRRGEEKLDALQRQNEELQSQLKESRHGEEKLDALQ 1619 Query: 1230 QRGFEI-AELWKQHLAQREAD-FQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIV 1287 ++ E+ ++L + + + D Q+ EL+ QL + E+ LD++Q +E +++ Sbjct: 1620 RQNEELRSQLKESRRGEEKLDALQRQNEELQSQLKE-SRRGEEKLDALQRQNEELQSQLK 1678 Query: 1288 TM----EQVTSLQNK---LQDKEEHLRNLQEKYADVINQIEILRSEIED 1329 E++ +LQ + LQ + + R +EK + Q E LRS++ + Sbjct: 1679 ESRRGEEKLDALQRQNEELQSQLKESRRGEEKLDALQRQNEELRSQLRE 1727 Score = 111 bits (267), Expect = 2e-22 Identities = 171/809 (21%), Positives = 365/809 (45%), Gaps = 69/809 (8%) Query: 480 KVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQ 539 ++Q QLK+ E K ++ E+L+S ++ + +++DA + +++S +LK+ Sbjct: 1144 ELQSQLKESRRGEEKLDALQRQNEQLQSQLKESRRGEEKLDALQRQNEQLQS----QLKE 1199 Query: 540 MQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVY 599 ++ + + N+E+ +E +K+ L+ + LQ L + G + Sbjct: 1200 SRRGEEKLDALQRQNEELQSQLKESRRGEEKLDALQRQNEELQSQLKESRRGEEKLDALQ 1259 Query: 600 KKMIEMEN-LAETRL--KAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVC 656 ++ E+++ L E+R + + L+ Q L +L ++ E+KL D Q Q++++ Sbjct: 1260 RQNEELQSQLKESRRGEEKLDALQRQNEQLQSQL----KESRRGEEKL-DALQRQNEELQ 1314 Query: 657 SEIK-SVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQ 715 S++K S EE++DAL +EL ++ + +E+L L+ E++ ++L+ + Sbjct: 1315 SQLKESRRGEEKLDALQRQNEELQSQLKESRRGEEKLDA----LQRQNEELQSQLKES-R 1369 Query: 716 ENMDLTDKLEKMSAEKISELLAKINHEEQ-SKIQTQFG-IDAKIQERDLYIENIESELSK 773 + D L++ + E S+L EE+ +Q Q + ++++E E +++ + Sbjct: 1370 RGEEKLDALQRQNEELQSQLKESRRGEEKLDALQRQNEQLQSQLKESRRGEEKLDALQRQ 1429 Query: 774 YKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDH 833 + +L+ES E++ +L+R+ +QL S L+E ++ + + + +L + Sbjct: 1430 NEELQSQLKESRRG-EEKLDALQRQNEQLQSQLKESRRGEEKLDALQRQN-EQLQSQLKE 1487 Query: 834 DRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESES 893 R E++L ++ +N+ELQ + L+E++ + L +Q+ L + + E + Sbjct: 1488 SRRGEEKLDALQRQNEELQSQ----LKESRRGEEKLDALQRQNEELRSQLKESRRGEEKL 1543 Query: 894 TKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKN 953 Q Q L+S LK + L +++ N Q++S +++ + EK + Sbjct: 1544 DALQRQNEQLQSQLKESRRGEEKLDALQRQ---------NEQLQSQLKESRRGEEKLDAL 1594 Query: 954 IEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINK 1013 +L++QL+E ++ E L + L + N EL + Q + E+ ++ + + Sbjct: 1595 QRQNEELQSQLKESRHGEEKL----DALQRQNEEL------RSQLKESRRGEEKLDALQR 1644 Query: 1014 LNALLKQKDEEIIALNQKINNAQVSYMSMVSDY-ESKLAQFTTKLENMEEEMQRVSKQLL 1072 N L+ + +E +K++ Q + S ES+ + KL+ ++ + + + QL Sbjct: 1645 QNEELQSQLKESRRGEEKLDALQRQNEELQSQLKESRRGE--EKLDALQRQNEELQSQLK 1702 Query: 1073 DSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXX 1132 +S++ E+L L R+ ++ +L+ET E K E S E + D Sbjct: 1703 ESRRGEEKLDALQRQNEELRSQLRETCRGPE----KLE----SEEEEEAAHQLVAEDESE 1754 Query: 1133 XXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVN 1192 E E ++ L+ Q KL +L+E +L+ L H+ Sbjct: 1755 AMTAALGEASGKPEAAELQRQLDALRRQKEKLRLQLREARRGQEKLDILRR----HNEDL 1810 Query: 1193 QEQINQLK---SKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREAD 1249 Q ++N + KL+ L N+ L S + E R + + D R +Q Q E D Sbjct: 1811 QSRLNDARRGQEKLDALQRHNEELQSQLCEARRAEEALEDAR-----RQTRQSQRQVE-D 1864 Query: 1250 FQKTEHELRVQLSAFESKYEQLLDSVQSS 1278 +++E LR A ++ E L+ ++++ Sbjct: 1865 LRRSEKRLREACEATRAREEALMQKLRAA 1893 Score = 83.8 bits (198), Expect = 4e-14 Identities = 152/824 (18%), Positives = 347/824 (42%), Gaps = 42/824 (5%) Query: 305 EEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSK 364 EEK + ++ + E+ + + +++ E E L+ RQ N+EL+++L + + + + Sbjct: 1228 EEKLDALQRQNEELQSQLKESRRGE--EKLDALQRQ-NEELQSQLKESRRGEEKLDALQR 1284 Query: 365 KGSPLISR-KSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVD 423 + L S+ K R K+ + Q + E +Q + + + ++ L+ + L L + Sbjct: 1285 QNEQLQSQLKESRRGEEKLDALQRQ-NEELQSQLKESRRGEEKLDALQRQNEELQSQLKE 1343 Query: 424 KEYVISEKDTXXXXXXXXXXG-KDTLIAQLQLE--HQQHMEGPSLIHVGTNTED-VNEIA 479 + D K++ + +L+ +Q+ E S + E+ ++ + Sbjct: 1344 SRRGEEKLDALQRQNEELQSQLKESRRGEEKLDALQRQNEELQSQLKESRRGEEKLDALQ 1403 Query: 480 KVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLK--L 537 + EQL+ +L + + D +++ EE +QL + K + N +L+ L Sbjct: 1404 RQNEQLQSQLKESRRGEEKLDALQRQN--EELQSQLKESRRGEEKLDALQRQNEQLQSQL 1461 Query: 538 KQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESD 597 K+ ++ + + N+++ +E +K+ L+ + LQ L + G Sbjct: 1462 KESRRGEEKLDALQRQNEQLQSQLKESRRGEEKLDALQRQNEELQSQLKESRRGEEKLDA 1521 Query: 598 VYKKMIEMEN-LAETRL--KAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQ 654 + ++ E+ + L E+R + + L+ Q L +L ++ E+KL D Q Q++Q Sbjct: 1522 LQRQNEELRSQLKESRRGEEKLDALQRQNEQLQSQL----KESRRGEEKL-DALQRQNEQ 1576 Query: 655 VCSEIK-SVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMN----- 708 + S++K S EE++DAL +EL ++ + +E+L + E + + Sbjct: 1577 LQSQLKESRRGEEKLDALQRQNEELQSQLKESRHGEEKLDALQRQNEELRSQLKESRRGE 1636 Query: 709 -KLQNYIQENMDLTDKL-EKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIEN 766 KL ++N +L +L E E+ + L + N E QS+++ + K+ E Sbjct: 1637 EKLDALQRQNEELQSQLKESRRGEEKLDALQRQNEELQSQLKESRRGEEKLDALQRQNEE 1696 Query: 767 IESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNR 826 ++S+L + + +L+ E+ R L E+++ + + EDE Sbjct: 1697 LQSQLKESRRGEEKLDALQRQNEELRSQLRETCRGPEKLESEEEEEAAHQLVAEDESEAM 1756 Query: 827 LAVLMDHDRVVEKQLLEIEHENKELQK-KNQILLEENQNLQISLSDMQQHYNALVEKANR 885 A L + E L+ + + QK K ++ L E + Q L +++H L + N Sbjct: 1757 TAALGEASGKPEAAELQRQLDALRRQKEKLRLQLREARRGQEKLDILRRHNEDLQSRLND 1816 Query: 886 TDLAESESTKYQTQLRDLESNLKRITHEHQTL------IVQKKKEIEDLEIEFNTQIESA 939 + + Q +L+S L + L Q ++++EDL ++ A Sbjct: 1817 ARRGQEKLDALQRHNEELQSQLCEARRAEEALEDARRQTRQSQRQVEDLR-RSEKRLREA 1875 Query: 940 IRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIEN-----LNMNVEELNKMNLELIDKHVQ 994 + E + + A +++++ ++ +N E + L + Sbjct: 1876 CEATRAREEALMQKLRAAENAIAVARKHEDAVKQKARGIINAVKTEYQRQPFVLPEPQET 1935 Query: 995 KQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFT 1054 +Q ++ D ++E L+ ++E L + + ++ + + + A+ Sbjct: 1936 EQLQRANDSPRAPLDEPPLTKEGLESEEEAAHQLMAEDESEAMTAALGEASGKPEAAELQ 1995 Query: 1055 TKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKET 1098 +L+ + + +++ QL ++++ E+L IL R+ ++ +L+ET Sbjct: 1996 RQLDALRRQKEKLRLQLREARRGQEKLDILQRQNEELRSQLRET 2039 Score = 80.2 bits (189), Expect = 4e-13 Identities = 155/839 (18%), Positives = 361/839 (43%), Gaps = 53/839 (6%) Query: 780 RLEESIAVMEDRRYSLERKADQLGSYLQEK-QKAYSEYTIQEDELVNRLAVLMDHDRVVE 838 ++E++ A + R +K+D LQE K E +Q+ + N+ ++++ Sbjct: 853 KVEDTSAFKKGREEDNVKKSDNKQQSLQEMFVKQQEEEELQQFQQKNKHIQKTENEQQHV 912 Query: 839 KQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQT 898 K + E QK+ I + Q + I ++ + E+ + + K Sbjct: 913 KSKIIPTTSKSENQKEKAIPQNKLQKV-IKKTEKHSITRQITEETKQNTIPIK---KVPA 968 Query: 899 QLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVT 958 Q +D N K+ + E + + K + L+ + N +++S +++ + EK + Sbjct: 969 QNKDFHENTKQNSDERKHTM----KTMAGLQRQ-NEELQSQLKESRRGEEKLDALQRQNE 1023 Query: 959 QLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALL 1018 QL++QL+E E L + L + N EL + Q + E+ ++ + + N L Sbjct: 1024 QLQSQLKESCRGEEKL----DALQRQNEEL------QSQLKESRRGEEKLDALQRQNEEL 1073 Query: 1019 KQKDEEIIALNQKINNAQVSYMSMVSDY-ESKLAQFTTKLENMEEEMQRVSKQLLDSKQH 1077 + + +E +K++ Q + S ES+ + KL+ ++ + +++ QL +S++ Sbjct: 1074 QSQLKESRRGEEKLDALQRQNEQLQSQLKESRRGE--EKLDALQRQNEQLQSQLRESRRG 1131 Query: 1078 NEELQILVREQDDQIKELKETKLTFE-MNIPKTEGMIISSTIEPMSDDANNVDXXXXXXX 1136 E+L L R+ ++ +LKE++ E ++ + + + S ++ +D Sbjct: 1132 EEKLDALQRQNEELQSQLKESRRGEEKLDALQRQNEQLQSQLKESRRGEEKLDALQRQNE 1191 Query: 1137 XXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQ-EQ 1195 LK E ++ LQ Q+ +L ++L+E +L+ L + ++ +Q ++ Sbjct: 1192 QLQSQLKESRRGE--EKLDALQRQNEELQSQLKESRRGEEKLDALQRQ--NEELQSQLKE 1247 Query: 1196 INQLKSKLEQLNTENDNLLSTVAELRSSIS--SAVDQRGFEI-AELWKQHLAQREAD-FQ 1251 + + KL+ L +N+ L S + E R A+ ++ ++ ++L + + + D Q Sbjct: 1248 SRRGEEKLDALQRQNEELQSQLKESRRGEEKLDALQRQNEQLQSQLKESRRGEEKLDALQ 1307 Query: 1252 KTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTM----EQVTSLQ---NKLQDKEE 1304 + EL+ QL + E+ LD++Q +E +++ E++ +LQ +LQ + + Sbjct: 1308 RQNEELQSQLKE-SRRGEEKLDALQRQNEELQSQLKESRRGEEKLDALQRQNEELQSQLK 1366 Query: 1305 HLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQE 1364 R +EK + Q E L+S++++ + L+ + +++ Sbjct: 1367 ESRRGEEKLDALQRQNEELQSQLKESRRG-EEKLDALQRQNEQLQSQLKESRRGEEKL-- 1423 Query: 1365 QSILNINEE-NAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEY 1423 ++ NEE +QLK+S R N+ L+ + + E K + ++ + Sbjct: 1424 DALQRQNEELQSQLKES--RRGEEKLDALQRQNEQLQSQLKESRRGEEKLDALQRQNEQL 1481 Query: 1424 TITL--TQRNDE-FENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKES 1480 L ++R +E + +++Q E + ++++ +E A+ R + E+ + E Sbjct: 1482 QSQLKESRRGEEKLDALQRQNEELQSQLKESRRGEEKLDALQRQNEELRSQLKESRRGE- 1540 Query: 1481 EIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEI 1540 E++ ++ N ++ + +++ E AL+ + + E ++ L + Sbjct: 1541 --EKLDALQRQNEQLQSQLKESRRGEEKLDALQRQNEQLQSQLKESRRGEEKLDALQRQN 1598 Query: 1541 TNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDLAMYMLHQR 1599 LQ+ ++ S +K + ++ R + ++ +E LDA+ R +L + R Sbjct: 1599 EELQSQLKESRHGEEKLDALQRQNEELRSQLKESRRGEEKLDALQRQNEELQSQLKESR 1657 Score = 58.8 bits (136), Expect = 1e-06 Identities = 158/857 (18%), Positives = 356/857 (41%), Gaps = 71/857 (8%) Query: 754 DAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAY 813 D K+++ E++++ L + + +++ +A + D+ ER+ + + Q + Sbjct: 645 DRKMEDLIRRNEDLQALLKDSRRSMEKMQSVVATITDKNNEWEREITERQRQIVLLQASL 704 Query: 814 SEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQ 873 E T + NR+A L ++ QL + EN E K ++ + + + + + Sbjct: 705 DEATSERTFAENRIADLQRTVENLQNQLNVL--ENAETDYKTEMYKQTTKKEPL---EAR 759 Query: 874 QHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFN 933 ++ E RT + + + +T S K++T T +K E DLE + N Sbjct: 760 AKNDSPSEDFLRTQIGKLNPVEKET------SAAKQLT---GTKNQEKAGEQYDLE-KPN 809 Query: 934 TQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHV 993 T +N K KN + T + ++ + +N++ E K N ++ D Sbjct: 810 T---------PYINYKTTKNYVF-TSSGTKQEKSTSRTKNISCTAEPQLKQNKKVEDTSA 859 Query: 994 QKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQF 1053 K+ + + + + + +KQ++EE + Q+ N + +SK+ Sbjct: 860 FKKGREEDNVKKSDNKQQSLQEMFVKQQEEEELQQFQQKNKHIQKTENEQQHVKSKIIPT 919 Query: 1054 TTKLENMEEE---MQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTE 1110 T+K EN +E+ ++ K + +++H+ QI +E K+ + + +P + Sbjct: 920 TSKSENQKEKAIPQNKLQKVIKKTEKHSITRQI--------TEETKQNTIPIK-KVP-AQ 969 Query: 1111 GMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSV--LQEQSAKLNTEL 1168 + SD+ + L+ Q +E E + LQ Q+ +L ++L Sbjct: 970 NKDFHENTKQNSDERKHTMKTMAGLQRQNEELQSQLKESRRGEEKLDALQRQNEQLQSQL 1029 Query: 1169 QECYTKIIQLETLNTELTGHDVVNQ-EQINQLKSKLEQLNTENDNLLSTVAELRSSISSA 1227 +E +L+ L + ++ +Q ++ + + KL+ L +N+ L S + E R Sbjct: 1030 KESCRGEEKLDALQRQ--NEELQSQLKESRRGEEKLDALQRQNEELQSQLKESR------ 1081 Query: 1228 VDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIV 1287 RG E + ++ Q ++ +++ +L A + + EQL ++ S + E Sbjct: 1082 ---RGEEKLDALQRQNEQLQSQLKESRRG-EEKLDALQRQNEQLQSQLRESRRGEEKLDA 1137 Query: 1288 TMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXX 1347 Q LQ++L++ R +EK + Q E L+S++++ + Sbjct: 1138 LQRQNEELQSQLKES----RRGEEKLDALQRQNEQLQSQLKESRRG-EEKLDALQRQNEQ 1192 Query: 1348 XXXDLRTENQSYKQMQEQSILNINEE-NAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELT 1406 L+ + +++ ++ NEE +QLK+S R N+ L+ + Sbjct: 1193 LQSQLKESRRGEEKL--DALQRQNEELQSQLKES--RRGEEKLDALQRQNEELQSQLKES 1248 Query: 1407 HQLELKDSEIYQKTHEYTITL--TQRNDE-FENVRQQLVEYEKRIEDLTYEKESELAILR 1463 + E K + ++ E L ++R +E + +++Q + + ++++ +E A+ R Sbjct: 1249 RRGEEKLDALQRQNEELQSQLKESRRGEEKLDALQRQNEQLQSQLKESRRGEEKLDALQR 1308 Query: 1464 LKMHENANHYETMQKESEIERV-KLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEM 1522 + E+ + E +++ + + EEL ++ ES +++ L + EE ++ E Sbjct: 1309 QNEELQSQLKESRRGEEKLDALQRQNEELQSQLKESRRGEEKLDALQRQNEELQSQLKES 1368 Query: 1523 QTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLD 1582 + E ++ L + LQ+ ++ S +K + +Q + + ++ +E LD Sbjct: 1369 RRG----EEKLDALQRQNEELQSQLKESRRGEEKLDALQRQNEQLQSQLKESRRGEEKLD 1424 Query: 1583 AVPRAELDLAMYMLHQR 1599 A+ R +L + R Sbjct: 1425 ALQRQNEELQSQLKESR 1441 >UniRef50_A3LZ88 Cluster: Myosin-1; n=1; Pichia stipitis|Rep: Myosin-1 - Pichia stipitis (Yeast) Length = 1874 Score = 123 bits (297), Expect = 4e-26 Identities = 172/872 (19%), Positives = 355/872 (40%), Gaps = 71/872 (8%) Query: 781 LEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQ-------------EDELVNRL 827 LEES+ V+ED S K + S L+E +K+ S + EDE++ Sbjct: 819 LEESVKVLEDAEMS--EKVKDISSKLEEAEKSKSNLEDENSKLKEQEQINKLEDEIITTT 876 Query: 828 AVLMDHDRVVEKQLLE---IEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKAN 884 ++ D D +EK E I +E + K + +EN L + E +N Sbjct: 877 NLVKDKDLKLEKAKSEEAKISSRIREFESKINQMKQENNKLSEEKKLLDSKLKESSENSN 936 Query: 885 RTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIE---FNTQIESAIR 941 R S TK + + ++L+ + +H+ V+++K IEDL+ E + ES + Sbjct: 937 RNIADLSSLTKERDDFKSKLADLELVVKKHKLEKVEREKHIEDLKKEHASLKSSSESKVE 996 Query: 942 DKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSP 1001 D K L+ K E+ I + + + + + ++ L ++ ++ +LE D+ +Q+ ++ Sbjct: 997 DMKQLSRKLEEEISKNSLILPKHESLLDEVKKLK-DLLSKSESDLESKDREIQETMSKQK 1055 Query: 1002 DYTEQYINEINKLNALLKQKDE----EIIALNQKINNAQVSYMSMVSDYESKLAQFTTKL 1057 + E+ I + N LK++ E EI N ++ Q+ ++ +S E + Q T + Sbjct: 1056 LFEEENIKVLEGTNKALKKEVESHKDEIAQKNAQVEKLQIQ-VAKLSSLEKETEQLNTLV 1114 Query: 1058 ENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISST 1117 N E+Q + +QL DS + N+ L ++V + + K + I I+S Sbjct: 1115 TNQSLEIQNLQEQLSDSVRENKSLSVVVEKLKVDYDAARIAKEEYSDKI-----FILSKK 1169 Query: 1118 IEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQ 1177 + + ++A + + EEF + L E +A L E E + + Sbjct: 1170 LSELEEEAREKEIEKENQPPDPAFV-----EEFAHIKLKLNENTAALRKEKFENKKLVEE 1224 Query: 1178 LETLNTELTGHDVVNQEQI--NQLKSKLEQLNTENDNLLSTVAELRSSISSA--VDQRGF 1233 L L ++ I N+L+S+ E L++ ++ + S +L+ +S++ + Sbjct: 1225 LSMLRDRFHNESQQDRSPIKQNELRSRTETLDSLHEEINSLKLQLQQEMSNSQRAENYAI 1284 Query: 1234 EIAELWKQHLAQRE----ADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTM 1289 +I + + A R D++K E + ++S E K+E+ + S S E + I Sbjct: 1285 DIQKKLNRLSATRGINSWTDYEKKFRESQRRVSELEGKFEEFI-SADESFSEASRSISKS 1343 Query: 1290 EQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAF----XXXXXXXXXXX 1345 + + + + + Y D+ + R E+ K Sbjct: 1344 DSFGRISFSMTSNSD----FAQIYQDITKTLRTTREELTTSKSEILRLKSLLRESEDELY 1399 Query: 1346 XXXXXDLRTENQSYKQMQEQSIL---NINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKV 1402 + +T Y+ Q + + +N+ L + ++ AEA V Sbjct: 1400 SAKTANFKTSISDYEDKLAQLTVRHDTLRTKNSDLASNLELYKRRSEEYYDKLELAEAAV 1459 Query: 1403 LELTHQLELKDSEIYQKTHEYTITLTQRNDE---FENVRQQLVEYEKRIEDLTY---EKE 1456 E +++ + ++ + + + +R + E+ I+D + ++E Sbjct: 1460 QISKRHEESALNDLNETKNQLKLAKEEARTSQIMIKEIRTNNSKLEETIQDKNFAMKQQE 1519 Query: 1457 SELAILRLKMHENANHYETMQKESEI--ERVKLIEELNVKITESVSLNKQVAELNKALEE 1514 +++ L+ K++ + +YE +K + E + L +EL K SL K +L LE+ Sbjct: 1520 AKIKELKEKIYYHKKNYENKEKTDKYREEIITLNKELAFKTDTENSLIKDSKKLQLDLED 1579 Query: 1515 --EVAKTNEMQTALENQEIEIV-TLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQ 1571 + KT E AL+ + + ++ T D ++N + + + + + E Sbjct: 1580 LTKEKKTLEEDYALKIEHVNVLETRVDLLSNKSRQLENAQEINDRKIGNLNKQVSSLREL 1639 Query: 1572 LDNTMNK--ELLDAVPRAELDLAMYMLHQRDV 1601 +++ N+ ELL+ + E D + H+ D+ Sbjct: 1640 VESVTNQRDELLETKAKLE-DQLSELTHKLDL 1670 Score = 119 bits (287), Expect = 6e-25 Identities = 202/1022 (19%), Positives = 429/1022 (41%), Gaps = 81/1022 (7%) Query: 556 EIVRLTEELHHLSQKVAELEEEKGNLQ---LHLVDYDSGRMIESDVYK-------KMIEM 605 E ++E++ +S K+ E E+ K NL+ L + + +E ++ K +++ Sbjct: 827 EDAEMSEKVKDISSKLEEAEKSKSNLEDENSKLKEQEQINKLEDEIITTTNLVKDKDLKL 886 Query: 606 ENLAETRLKAISLL---ESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSV 662 E K S + ES+ + QE + L ++ ++ KL + S+ S++ +++ S Sbjct: 887 EKAKSEEAKISSRIREFESKINQMKQENNKLSEEKKLLDSKLKESSE-NSNRNIADLSS- 944 Query: 663 HLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTD 722 L ++ D + +L LV++ KL+K + I+DL+ + + + ++ +++ L+ Sbjct: 945 -LTKERDDFKSKLADLELVVKKHKLEKVEREKHIEDLKKEHASLKSSSESKVEDMKQLSR 1003 Query: 723 KLEKMSAEKISELLAKINHEE-QSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRL 781 KLE+ K S +L K HE +++ + +K E DL ++ E + + K ++ Sbjct: 1004 KLEE-EISKNSLILPK--HESLLDEVKKLKDLLSK-SESDLESKDREIQETMSKQKLFE- 1058 Query: 782 EESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQL 841 EE+I V+E +L+++ + + +K + IQ +L + + +V Q Sbjct: 1059 EENIKVLEGTNKALKKEVESHKDEIAQKNAQVEKLQIQVAKLSSLEKETEQLNTLVTNQS 1118 Query: 842 LEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNAL-VEKANRTDLAESESTKYQTQL 900 LEI++ LQ++ + EN++L + + ++ Y+A + K +D S K ++L Sbjct: 1119 LEIQN----LQEQLSDSVRENKSLSVVVEKLKVDYDAARIAKEEYSDKIFILSKKL-SEL 1173 Query: 901 RDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYV-TQ 959 + E+ K I E+Q +E ++++ N + +A+R +K N+K + + + + Sbjct: 1174 EE-EAREKEIEKENQPPDPAFVEEFAHIKLKLN-ENTAALRKEKFENKKLVEELSMLRDR 1231 Query: 960 LEAQLQEYKNNIE--NLNMNVEELNKMNLELIDKHVQKQQTQS-PDYTEQYINEI-NKLN 1015 + Q+ ++ I+ L E L+ ++ E+ +Q QQ S E Y +I KLN Sbjct: 1232 FHNESQQDRSPIKQNELRSRTETLDSLHEEINSLKLQLQQEMSNSQRAENYAIDIQKKLN 1291 Query: 1016 ALLKQKD-EEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSK----- 1069 L + +K +Q VS+ E K +F + E+ E + +SK Sbjct: 1292 RLSATRGINSWTDYEKKFRESQ----RRVSELEGKFEEFISADESFSEASRSISKSDSFG 1347 Query: 1070 QLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVD 1129 ++ S N + + ++ ++ +E T + I + + ++ S E S N Sbjct: 1348 RISFSMTSNSDFAQIYQDITKTLRTTREELTTSKSEILRLKSLLRESEDELYSAKTANFK 1407 Query: 1130 XXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHD 1189 L V+ + + S L +E Y K+ E H+ Sbjct: 1408 TSISDYEDKLAQLTVR-HDTLRTKNSDLASNLELYKRRSEEYYDKLELAEAAVQISKRHE 1466 Query: 1190 VVNQEQINQLKSKLEQLNTENDNLLSTVAELR---SSISSAVDQRGFEIAEL-WKQHLAQ 1245 +N+ K++L+ E + E+R S + + + F + + K + Sbjct: 1467 ESALNDLNETKNQLKLAKEEARTSQIMIKEIRTNNSKLEETIQDKNFAMKQQEAKIKELK 1526 Query: 1246 READFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEH 1305 + + K +E + + + + L + T E + I + LQ L+D + Sbjct: 1527 EKIYYHKKNYENKEKTDKYREEIITLNKELAFKTDTENSLI---KDSKKLQLDLEDLTKE 1583 Query: 1306 LRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQ 1365 + L+E YA I + +L + ++ + + ++ +++ ++ Sbjct: 1584 KKTLEEDYALKIEHVNVLETRVD-------------------LLSNKSRQLENAQEINDR 1624 Query: 1366 SILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTI 1425 I N+N++ + L++ E ++ ELTH+L+L ++E+ Q + I Sbjct: 1625 KIGNLNKQVSSLRELVESVTNQRDELLETKAKLEDQLSELTHKLDLSEAELAQTNKDMNI 1684 Query: 1426 TLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILR--LKMHENANHYETMQKESEIE 1483 T EN RQ+ E + + SE+ + K H ++ K+ E Sbjct: 1685 LRT----HLENQRQESSEIKSELSQSRSSISSEMQDYQKLRKEHLVSSEENITLKKINKE 1740 Query: 1484 RVKLIEELNVKITESVSL---NKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEI 1540 + EL K+ + L +V +L K L+ ++ +E ++N E ++ L +I Sbjct: 1741 LSSKVHELEEKLYGNEQLRFWEDKVRDLMKELDNSQSENHEASRTIKNLEKDVKQLEIKI 1800 Query: 1541 TN 1542 N Sbjct: 1801 AN 1802 Score = 93.9 bits (223), Expect = 3e-17 Identities = 197/931 (21%), Positives = 388/931 (41%), Gaps = 94/931 (10%) Query: 666 EQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKE--DIMNKLQNYIQENMDLTDK 723 +Q+D +S + L I N+K E+ ++D E ++ DI +KL+ + +L D+ Sbjct: 797 KQLDESRSSSLWMDLFI-NIKPLLEESVKVLEDAEMSEKVKDISSKLEEAEKSKSNLEDE 855 Query: 724 LEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEE 783 K+ ++ +IN E I T ++++DL +E +SE +K SRI E Sbjct: 856 NSKLKEQE------QINKLEDEIITTT----NLVKDKDLKLEKAKSEEAKISSRIREFES 905 Query: 784 SIAVMEDRRYSLERKADQLGSYLQEKQK-------AYSEYTIQEDELVNRLAVLMDHDRV 836 I M+ L + L S L+E + S T + D+ ++LA D + V Sbjct: 906 KINQMKQENNKLSEEKKLLDSKLKESSENSNRNIADLSSLTKERDDFKSKLA---DLELV 962 Query: 837 VEKQLLE-IEHEN--KELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESES 893 V+K LE +E E ++L+K++ L +++ + DM+Q L E+ ++ L Sbjct: 963 VKKHKLEKVEREKHIEDLKKEHASLKSSSES---KVEDMKQLSRKLEEEISKNSLI---L 1016 Query: 894 TKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKN 953 K+++ L +++ LK + + ++ + K +EI++ + +K+ E+ K Sbjct: 1017 PKHESLLDEVK-KLKDLLSKSESDLESKDREIQE-----------TMSKQKLFEEENIKV 1064 Query: 954 IEYVTQ-LEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEIN 1012 +E + L+ +++ +K+ I N VE+L +L ++K+ Q EI Sbjct: 1065 LEGTNKALKKEVESHKDEIAQKNAQVEKLQIQVAKL--SSLEKETEQLNTLVTNQSLEIQ 1122 Query: 1013 KLNALLKQKDEEIIALNQKINNAQVSYMS---MVSDYESKLAQFTTKLENMEEEMQRVSK 1069 L L E +L+ + +V Y + +Y K+ + KL +EEE + K Sbjct: 1123 NLQEQLSDSVRENKSLSVVVEKLKVDYDAARIAKEEYSDKIFILSKKLSELEEEAR--EK 1180 Query: 1070 QLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVD 1129 ++ ++ N+ E+ IK LK + T + K E + + + D +N Sbjct: 1181 EI---EKENQPPDPAFVEEFAHIK-LKLNENTAALRKEKFENKKLVEELSMLRDRFHNES 1236 Query: 1130 XXXXXXXXXXXXLKVQEEEEFIQER---SVLQEQSAKLNTELQECYTKIIQLETLNTELT 1186 E + + E LQ Q N++ E Y IQ + LN L+ Sbjct: 1237 QQDRSPIKQNELRSRTETLDSLHEEINSLKLQLQQEMSNSQRAENYAIDIQ-KKLN-RLS 1294 Query: 1187 GHDVVN-----QEQINQLKSKLEQLNTENDNLLS---TVAELRSSISSAVDQRGFEIAEL 1238 +N +++ + + ++ +L + + +S + +E SIS + + Sbjct: 1295 ATRGINSWTDYEKKFRESQRRVSELEGKFEEFISADESFSEASRSISKSDSFGRISFSMT 1354 Query: 1239 WKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQE-ETNKIVTME-QVTSLQ 1296 AQ D KT R +L+ +S+ +L ++ S E + K + ++ + Sbjct: 1355 SNSDFAQIYQDITKTLRTTREELTTSKSEILRLKSLLRESEDELYSAKTANFKTSISDYE 1414 Query: 1297 NKLQDKEEHLRNLQEKYADVINQIEIL--RSEIEDEKVAFX-XXXXXXXXXXXXXXXDLR 1353 +KL L+ K +D+ + +E+ RSE +K+ DL Sbjct: 1415 DKLAQLTVRHDTLRTKNSDLASNLELYKRRSEEYYDKLELAEAAVQISKRHEESALNDLN 1474 Query: 1354 TENQSYKQMQEQS------ILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTH 1407 K +E++ I I N++L+++ ++ + + K+ H Sbjct: 1475 ETKNQLKLAKEEARTSQIMIKEIRTNNSKLEETIQDKNFAMKQQEAKIKELKEKI--YYH 1532 Query: 1408 QLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKR----IEDLTYEKESELAILR 1463 + ++ E K E ITL + + L++ K+ +EDLT EK++ Sbjct: 1533 KKNYENKEKTDKYREEIITLNKELAFKTDTENSLIKDSKKLQLDLEDLTKEKKTLEEDYA 1592 Query: 1464 LKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQ 1523 LK+ E+ N ET + +L + + +LNKQV+ L + +E + TN+ Sbjct: 1593 LKI-EHVNVLETRVDLLSNKSRQLENAQEINDRKIGNLNKQVSSLRELVE---SVTNQRD 1648 Query: 1524 TALENQEIEIVTLNDEITNLQNMVRASSSKI 1554 LE + L D+++ L + + S +++ Sbjct: 1649 ELLETK----AKLEDQLSELTHKLDLSEAEL 1675 Score = 72.5 bits (170), Expect = 9e-11 Identities = 144/733 (19%), Positives = 300/733 (40%), Gaps = 49/733 (6%) Query: 164 KMKIMETTILDLQEKINEKDQIIEAKNK----ATTXXXXXXXXXXXXXXXXXEDTKQQMT 219 K+ I+ + +L+E+ EK+ IE +N+ A K + Sbjct: 1162 KIFILSKKLSELEEEAREKE--IEKENQPPDPAFVEEFAHIKLKLNENTAALRKEKFENK 1219 Query: 220 KMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELE 279 K+ E + + +E Q+ I+ ++R S E + L E EI+ +L QE+ Sbjct: 1220 KLVEELSMLRDRFHNESQQDRSPIKQNELR-SRTETLDSLHE----EINSLKLQLQQEMS 1274 Query: 280 QXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIR 339 L + S T+ E+K ++EL K E + Sbjct: 1275 NSQRAENYAIDIQKKLNRLSATRGINSWTDYEKKFRESQRRVSELEGKFEEFISADESFS 1334 Query: 340 QTNKELENKLATMGTESKAVSSPSKKGSPLIS-RKSGRNTASKMKSPWSQ-LSSETLNQD 397 + ++ + +K + G S +++S S K+ R T ++ + S+ L ++L ++ Sbjct: 1335 EASRSI-SKSDSFGRISFSMTSNSDFAQIYQDITKTLRTTREELTTSKSEILRLKSLLRE 1393 Query: 398 TDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQ 457 ++ ++ + A + I D DK ++ + L + E+ Sbjct: 1394 SEDELYSAKTANFKTSIS----DYEDKLAQLTVRHDTLRTKNSDLASNLELYKRRSEEYY 1449 Query: 458 QHME-GPSLIHVGTNTED--VNEIAKVQEQLKQELND-EIKDVNVKDLIEKLKSAEEQIT 513 +E + + + E+ +N++ + + QLK + + +K++ EE I Sbjct: 1450 DKLELAEAAVQISKRHEESALNDLNETKNQLKLAKEEARTSQIMIKEIRTNNSKLEETI- 1508 Query: 514 QLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAE 573 D+ A + K+K K K+ +K +N K +EI+ L +EL + Sbjct: 1509 --QDKNFAMKQQEAKIKEL-KEKIYYHKKNYENKEKTDKYREEIITLNKELAFKTDTENS 1565 Query: 574 LEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELH-- 631 L ++ LQL L D + + Y IE N+ ETR+ +S +S++ + QE++ Sbjct: 1566 LIKDSKKLQLDLEDLTKEKKTLEEDYALKIEHVNVLETRVDLLS-NKSRQLENAQEINDR 1624 Query: 632 ---ILQQKYDEVEDKLADISQLQSDQVCSEIK-SVHLEEQIDALSASKKELALVIENLKL 687 L ++ + + + ++ + + + ++ K L E L S+ ELA +++ + Sbjct: 1625 KIGNLNKQVSSLRELVESVTNQRDELLETKAKLEDQLSELTHKLDLSEAELAQTNKDMNI 1684 Query: 688 ------DKEQLYGTIK-DLENDKEDIMNKLQNYIQENMD-LTDKLEKMSAEKISELLAKI 739 ++ Q IK +L + I +++Q+Y + + L E ++ +KI++ L+ Sbjct: 1685 LRTHLENQRQESSEIKSELSQSRSSISSEMQDYQKLRKEHLVSSEENITLKKINKELSSK 1744 Query: 740 NHEEQSKI----QTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSL 795 HE + K+ Q +F D K+++ ++N +SE + I LE+ + +E + + Sbjct: 1745 VHELEEKLYGNEQLRFWED-KVRDLMKELDNSQSENHEASRTIKNLEKDVKQLEIKIANE 1803 Query: 796 ERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKN 855 + + + Q S Y D L N + R E++ + ++ L+K+ Sbjct: 1804 AQLRKKYNDENFDYQNKVSHYKSSLDILQNEQSEKDLQIRTAERENINLKESKLSLEKE- 1862 Query: 856 QILLEENQNLQIS 868 +LE Q L I+ Sbjct: 1863 --VLELRQRLGIN 1873 Score = 70.9 bits (166), Expect = 3e-10 Identities = 185/994 (18%), Positives = 398/994 (40%), Gaps = 102/994 (10%) Query: 143 DVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXX 202 ++ LS+ KE+D+ S L +++ L EK+ E+++ IE K Sbjct: 938 NIADLSSLTKERDDFKSKLADLELVVKKHKL---EKV-EREKHIEDLKKEHASLKSSSES 993 Query: 203 XXXXXXXXXEDTKQQMTK------MQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEA 256 +++++K E+ + + KD + D+ESKD I Sbjct: 994 KVEDMKQLSRKLEEEISKNSLILPKHESLLDEVKKLKDLLSKSESDLESKDREIQETMSK 1053 Query: 257 NKLLEAARFEISLEHSK-LAQELEQXXXXXXXXXXXXXXLAKQ-----SIEPSCEEKTEI 310 KL E ++ +K L +E+E L Q S+E E+ + Sbjct: 1054 QKLFEEENIKVLEGTNKALKKEVESHKDEIAQKNAQVEKLQIQVAKLSSLEKETEQLNTL 1113 Query: 311 EEKGSLEIANMTE-LTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPL 369 SLEI N+ E L+ + + L+ + + + + S + SKK S L Sbjct: 1114 VTNQSLEIQNLQEQLSDSVRENKSLSVVVEKLKVDYDAARIAKEEYSDKIFILSKKLSEL 1173 Query: 370 ISRKSGRNTASKMKSPWSQLSSE------TLNQDT-----DKKINKNEIAKLEMVIQSLN 418 + + + P E LN++T +K NK + +L M+ + Sbjct: 1174 EEEAREKEIEKENQPPDPAFVEEFAHIKLKLNENTAALRKEKFENKKLVEELSMLRDRFH 1233 Query: 419 KDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEI 478 + I + + ++ +LQL+ + + + + +N + Sbjct: 1234 NESQQDRSPIKQNELRSRTETLDSLHEEINSLKLQLQQEMSNSQRAENYAIDIQKKLNRL 1293 Query: 479 AKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLK 538 + + + + E K + + +L+ E+ ++ A++++ K S ++ Sbjct: 1294 SATR-GINSWTDYEKKFRESQRRVSELEGKFEEFISADESFSEASRSISKSDSFGRISFS 1352 Query: 539 QMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDV 598 + +F+++ + +R T E L+ +E+ K L+ + S + Sbjct: 1353 MTSNS--DFAQIYQDITKTLRTTRE--ELTTSKSEILRLKSLLRESEDELYSAKTANFKT 1408 Query: 599 YKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSE 658 E + LA+ ++ L ++ DL L + +++ +E DK L+ + + Sbjct: 1409 SISDYE-DKLAQLTVRH-DTLRTKNSDLASNLELYKRRSEEYYDK------LELAEAAVQ 1460 Query: 659 IKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENM 718 I H E ++ L+ +K +L L E + + IK++ + +KL+ IQ+ Sbjct: 1461 ISKRHEESALNDLNETKNQLKLAKEEARTSQIM----IKEIRTNN----SKLEETIQDK- 1511 Query: 719 DLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRI 778 + K KI EL KI + +++ EN E + KY+ I Sbjct: 1512 ---NFAMKQQEAKIKELKEKIYYHKKN------------------YENKE-KTDKYREEI 1549 Query: 779 CRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVE 838 L + +A D SL + + +L L++ K + T++ED A+ ++H V+E Sbjct: 1550 ITLNKELAFKTDTENSLIKDSKKLQLDLEDLTK--EKKTLEED-----YALKIEHVNVLE 1602 Query: 839 KQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQT 898 ++ + +++++L+ +I + NL +S +++ ++ + R +L E+++ K + Sbjct: 1603 TRVDLLSNKSRQLENAQEINDRKIGNLNKQVSSLRELVESVTNQ--RDELLETKA-KLED 1659 Query: 899 QLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEK----YEKNI 954 QL +L L E + Q K++ L Q + + K L++ + Sbjct: 1660 QLSELTHKLDLSEAE----LAQTNKDMNILRTHLENQRQESSEIKSELSQSRSSISSEMQ 1715 Query: 955 EYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQS-PDYTEQYINEI-- 1011 +Y + L + NI +N E +K++ EL +K +Q + D + E+ Sbjct: 1716 DYQKLRKEHLVSSEENITLKKINKELSSKVH-ELEEKLYGNEQLRFWEDKVRDLMKELDN 1774 Query: 1012 -----NKLNALLKQKDEEIIALNQKI-NNAQV--SYMSMVSDYESKLAQFTTKLENMEEE 1063 ++ + +K ++++ L KI N AQ+ Y DY++K++ + + L+ ++ E Sbjct: 1775 SQSENHEASRTIKNLEKDVKQLEIKIANEAQLRKKYNDENFDYQNKVSHYKSSLDILQNE 1834 Query: 1064 MQRVSKQLLDSKQHNEELQILVREQDDQIKELKE 1097 Q+ +++ N L+ + ++ EL++ Sbjct: 1835 QSEKDLQIRTAERENINLKESKLSLEKEVLELRQ 1868 >UniRef50_Q54JG6 Cluster: Putative uncharacterized protein; n=1; Dictyostelium discoideum AX4|Rep: Putative uncharacterized protein - Dictyostelium discoideum AX4 Length = 2037 Score = 123 bits (296), Expect = 5e-26 Identities = 242/1391 (17%), Positives = 544/1391 (39%), Gaps = 112/1391 (8%) Query: 212 EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271 E++ +++T +Q A+ K+ ++L K+ E +EEA +LEA ++ E Sbjct: 290 EESSKKVTLLQNRLDAL----KEADKKLRKEHEDA---YHKMEEAYDILEADYQKVIKEF 342 Query: 272 SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKI-EL 330 + Q + Q P + + + + + EL +++ ++ Sbjct: 343 DEFKQHTQANAQNQSFNGVGSSSDLSQMDIPILSDTVKERLSDATTLGSRDELRRELLDM 402 Query: 331 LEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGR-----NTASKMKSP 385 ++ + + E + K S + KK +PLI ++ + K+ + Sbjct: 403 IQRYDDLTKIALNEKKEKRYVQDHLSHILREVEKK-APLIHEQNREYQRLLKSQEKLLNS 461 Query: 386 WSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGK 445 + QL S+ +E KL+ I L K + ++ E K Sbjct: 462 YQQLQSQKETLSLKVTTISSENNKLKQEINDLQKQI---RCLLQEALEKKQLQSQSQLNK 518 Query: 446 DTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKL 505 Q Q + G S+++ T+T + I + + L N E + +DL+ ++ Sbjct: 519 SQFNGQ-----QSTLFGNSVLNNSTSTSSDDSI--IPDSLITFTNIEELQLRNQDLLRQI 571 Query: 506 KSAEEQITQLND---EIDAANKNMIKVKSNHKLKLKQMQKTI---DNFSKVSDSNKEIVR 559 + + I N+ +++ A K + +K+ + + + +Q + D++ VS N Sbjct: 572 RILSQDIQSHNENDKKLEMALKELDHLKTARERQAEMIQSLVKQRDHYKNVSSPN----- 626 Query: 560 LTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLL 619 ++ ++ + G + L + + M+ I N + S Sbjct: 627 -SQPINQVGNNNNNNSSSGGMMTLSDLSSSTNGMLNDSSMNGSINKNNNNNNSMND-SFN 684 Query: 620 ESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELA 679 S K + + + L S L Q +EI + LE+ + +K+ Sbjct: 685 NSIKNNN-------NNNNNNNNNSLLSSSTLIQQQQSNEILTQELEKIKQSYQLLQKDYE 737 Query: 680 LVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKI 739 V+++ + ++L G I+ + + ++ EN ++L+ +S + + + Sbjct: 738 QVMKDRSISDKELLGKIEQMREQNTSLKIQISQIQSENTIFKERLQ-ISTDSVKNQSQDL 796 Query: 740 NHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKA 799 EQ + + Q +DA ++ + IEN+ S+LS+ + + E ++ ++ + Sbjct: 797 ---EQYRKKNQELMDAVVRHQQS-IENLNSQLSRSEEFKSQAELRLSNIKGENQLIRASE 852 Query: 800 DQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILL 859 ++L E K S + + L++++ L K+ E E + +N + L Sbjct: 853 ERL----IEMNKTLSLEKLSIENLLDKVNQLN-----ASKESSETELRRRI---ENDLTL 900 Query: 860 EENQNLQISLS---DMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQT 916 E Q +Q+ + QQH + ++ + + K + +L DL+ ++ ++ QT Sbjct: 901 LETQRIQLKKELDQEKQQHKETSIAMTHQINESRERFEKKEKELSDLKESIIKLKVSEQT 960 Query: 917 LIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNM 976 L+ ++I LE + N +S +R ++ + + L NN N Sbjct: 961 LL----QKITFLENQLN---QSELRYNTIIERTQSNQLTISPTTSSTLSTNNNNNNNQQQ 1013 Query: 977 NVEELNKMNLELIDKHVQKQQTQS-PDYTEQYINEINKLNALLKQKDEEIIALNQKINNA 1035 +++ + + +D + K + +S D Q + I ++ + ++ L ++ Sbjct: 1014 KLQQQQQQQQDNLDLSLAKSEIESLKDLLAQEKDNIVHYKSIAISNENDLSQLKEEYTKT 1073 Query: 1036 QVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKEL 1095 +V + D +++LA+ E ++E+ ++ K S H +++ ++ E+D + E Sbjct: 1074 KVELEERLKDAQAELAK---SQETIKEQQIKLEKLENFSSSHQKDINSIIAEKDSILAEK 1130 Query: 1096 KETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEE--EEFIQE 1153 ++ + + K + + + + +KV + ++ ++ Sbjct: 1131 QQLYEKIQQ-LTKDQQLALDEAKLQHQLCRKATENYEREVVLHAEDIKVLPKLRDDLVEA 1189 Query: 1154 RSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNL 1213 R + + K+++ QE LE + + ++QI +L+ +L+ L N+ L Sbjct: 1190 RKTINQMQIKIDSNSQE-------LEQAKQSWIQQEQLLKQQIQELEERLKDLKHHNNLL 1242 Query: 1214 LSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLL- 1272 S + + + L Q D EL VQ+ A E K ++ Sbjct: 1243 HSQIENINQQTQQIDRYSQLSSSSSVGNGLVQVSEDEINNLKEL-VQVQAREQKITEVKN 1301 Query: 1273 DSVQSSTQEETNKIVTMEQ-VTSLQNKLQDKEEHLRNLQ---EKYADVINQIEILRSEIE 1328 +S+Q + I ++ + ++ KLQ+++E++R L K+ +V+ Q+E + Sbjct: 1302 ESLQQENIRLKSTIAANQKAIETVTKKLQEEQENMRTLTVSTRKHQEVLAQLEQMN---- 1357 Query: 1329 DEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXX 1388 F ++ + KQ Q+ +L + E N +L + Sbjct: 1358 ----LFKESNIMLKDETRKLGAQVQELQEKLKQSQDH-LLPLTESNKKLLAENQILHNEI 1412 Query: 1389 XXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRI 1448 + + KV +L ++ + D E++QK E T + N E + QQL + +K++ Sbjct: 1413 EAQKIEITNWSGKVQKLLNKYQSIDPEVHQKLLETNETTIRENQE---LTQQLEDLKKQL 1469 Query: 1449 EDLTYEKESELAILR-LKMHENANHYETMQ-KESEIE-------RVKLIEELNVKITESV 1499 EDL + E LK H E ++ K+ ++E + +L ++ + Sbjct: 1470 EDLKKQLEDNKKQYEDLKKHTKHWKEEAVKFKKDKLELDQSLTQQKELFSTTKQQLDSNT 1529 Query: 1500 SLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVS 1559 + N+Q + N+ L +++ N + A + Q + N+EI L+ + + + + Sbjct: 1530 ATNEQTLKENQELRKKIQIANANKQANKQQIQQQQANNEEIEALKKQLEDTRKLAEDYKK 1589 Query: 1560 FASDTKQGRDE 1570 A D K+ DE Sbjct: 1590 LADDYKKLTDE 1600 Score = 88.6 bits (210), Expect = 1e-15 Identities = 261/1364 (19%), Positives = 547/1364 (40%), Gaps = 118/1364 (8%) Query: 306 EKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNK---------ELENKLATMGTES 356 EK ++ K +E N +T K +L + L I + +K EL+ + + + + Sbjct: 69 EKDYMDSKKDVEQLNKQNITIKKDL-QSLKLSIERESKSNTLNRFIDELQQEKSNLHSII 127 Query: 357 KAVSSPSKKGSPLISRKSGR-NTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQ 415 + K+ + +S+ + R N K KS L S+ + + + N+ +I +L+ + Sbjct: 128 ERKEKDLKEETETVSKLTERLNEFIKEKS---DLKSKLITVENENSSNEFQIQRLKQEVN 184 Query: 416 SLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDV 475 L K E S+K T K+ L+L+ + + ++ + +++ Sbjct: 185 ELRKQTTFLED--SQKQTTNNLFNEI---KELKSFNLELKLKNENQADEILKLNQINQNL 239 Query: 476 NEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKL 535 + E+ Q+LN+EIK + EK++ T+LN + + A+ + + + K Sbjct: 240 KKQTSELEKKNQQLNEEIKKITT----EKVQMTSSFETELNSQKNLASLYQERSEESSK- 294 Query: 536 KLKQMQKTIDNF----SKVSDSNKEIVRLTEELHHL----SQKV-AELEEEKGNLQLHLV 586 K+ +Q +D K+ +++ EE + + QKV E +E K + Q + Sbjct: 295 KVTLLQNRLDALKEADKKLRKEHEDAYHKMEEAYDILEADYQKVIKEFDEFKQHTQANAQ 354 Query: 587 DYD-SGRMIESDVYKKMIE-MENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKL 644 + +G SD+ + I + + + RL + L S+ +L +EL + Q+YD++ K+ Sbjct: 355 NQSFNGVGSSSDLSQMDIPILSDTVKERLSDATTLGSRD-ELRRELLDMIQRYDDL-TKI 412 Query: 645 ADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKE 704 A + + V + H+ +++ + E + L +E+L + + L++ KE Sbjct: 413 ALNEKKEKRYVQDHLS--HILREVEKKAPLIHEQNREYQRLLKSQEKLLNSYQQLQSQKE 470 Query: 705 DIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFG-IDAKIQERDLY 763 + K+ EN L ++ + ++I LL + ++Q + Q+Q Q+ L+ Sbjct: 471 TLSLKVTTISSENNKLKQEINDLQ-KQIRCLLQEALEKKQLQSQSQLNKSQFNGQQSTLF 529 Query: 764 IENIESELSKYKSRICRLEES------IAVMEDRRYSLERKADQLGSYLQEKQKAYSEYT 817 ++ + + S + +S I ++ R L R+ L +Q + + Sbjct: 530 GNSVLNNSTSTSSDDSIIPDSLITFTNIEELQLRNQDLLRQIRILSQDIQSHNENDKKLE 589 Query: 818 IQEDELVNRLAVLMDHDRVVEKQLLEIEH----ENKELQKKNQILLEENQNL----QISL 869 + EL + +++ + + +H + Q NQ+ N N ++L Sbjct: 590 MALKELDHLKTARERQAEMIQSLVKQRDHYKNVSSPNSQPINQVGNNNNNNSSSGGMMTL 649 Query: 870 SDMQQHYNALVEKA-----------NRTDLAESESTKYQTQLRDLESNLKRITHEHQTLI 918 SD+ N ++ + N + +S + + + +N TLI Sbjct: 650 SDLSSSTNGMLNDSSMNGSINKNNNNNNSMNDSFNNSIKNNNNNNNNNNNNSLLSSSTLI 709 Query: 919 VQKK-KEIEDLEIEFNTQIESAIRD--KKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLN 975 Q++ EI E+E Q ++ ++V+ ++ + E + ++E Q++E +++ Sbjct: 710 QQQQSNEILTQELEKIKQSYQLLQKDYEQVMKDRSISDKELLGKIE-QMREQNTSLKIQI 768 Query: 976 MNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNA 1035 ++ N + E + + QS D EQY + +L + + + I LN +++ + Sbjct: 769 SQIQSENTIFKERLQISTDSVKNQSQD-LEQYRKKNQELMDAVVRHQQSIENLNSQLSRS 827 Query: 1036 QVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKEL 1095 + + S S + + EE + ++K L K E L V Q + KE Sbjct: 828 E-EFKSQAELRLSNIKGENQLIRASEERLIEMNKTLSLEKLSIENLLDKV-NQLNASKES 885 Query: 1096 KETKL--TFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQE 1153 ET+L E ++ E I E + + + + E++E +E Sbjct: 886 SETELRRRIENDLTLLETQRIQLKKELDQEKQQHKETSIAMTHQINESRERFEKKE--KE 943 Query: 1154 RSVLQEQSAKLNTELQECYTKIIQLET-LN-TELTGHDVVNQEQINQL---KSKLEQLNT 1208 S L+E KL Q KI LE LN +EL + ++ + Q NQL + L+T Sbjct: 944 LSDLKESIIKLKVSEQTLLQKITFLENQLNQSELRYNTIIERTQSNQLTISPTTSSTLST 1003 Query: 1209 ENDNLLSTVAELRSSISSAVDQRGFEIA----ELWKQHLAQRE---ADFQKTEHELRVQL 1261 N+N + +L+ D +A E K LAQ + ++ L Sbjct: 1004 NNNNNNNQQQKLQQQQQQQQDNLDLSLAKSEIESLKDLLAQEKDNIVHYKSIAISNENDL 1063 Query: 1262 SAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIE 1321 S + +Y + ++ ++ ++ ++ Q Q K E L N + IN I Sbjct: 1064 SQLKEEYTKTKVELEERLKDAQAELAKSQETIKEQ---QIKLEKLENFSSSHQKDINSII 1120 Query: 1322 ILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQE----QSILNINEENAQL 1377 + I EK + + ++Q ++ E + +L+ + Sbjct: 1121 AEKDSILAEKQQLYEKIQQLTKDQQLALDEAKLQHQLCRKATENYEREVVLHAEDIKVLP 1180 Query: 1378 KKSSXXXXXXXXXXXXRVN-DAEAKVLELTHQLELKDSEI----YQKTHEYTITLTQRND 1432 K ++ D+ ++ LE Q ++ ++ Q+ E L N+ Sbjct: 1181 KLRDDLVEARKTINQMQIKIDSNSQELEQAKQSWIQQEQLLKQQIQELEERLKDLKHHNN 1240 Query: 1433 ----EFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQ---KESEIERV 1485 + EN+ QQ + + R L+ ++++ E N E +Q +E +I V Sbjct: 1241 LLHSQIENINQQTQQID-RYSQLSSSSSVGNGLVQVSEDEINNLKELVQVQAREQKITEV 1299 Query: 1486 K--LIEELNVKITESVSLNKQVAE-LNKALEEEVAKTNEMQTALENQEIEIVTLNDEITN 1542 K +++ N+++ +++ N++ E + K L+EE + + + E++ +++ Sbjct: 1300 KNESLQQENIRLKSTIAANQKAIETVTKKLQEEQENMRTLTVSTRKHQ-EVLAQLEQMNL 1358 Query: 1543 LQN---MVRASSSKIQKHV-SFASDTKQGRDEQLDNT-MNKELL 1581 + M++ + K+ V KQ +D L T NK+LL Sbjct: 1359 FKESNIMLKDETRKLGAQVQELQEKLKQSQDHLLPLTESNKKLL 1402 Score = 87.8 bits (208), Expect = 2e-15 Identities = 211/1135 (18%), Positives = 461/1135 (40%), Gaps = 97/1135 (8%) Query: 491 DEIKDVNVKDLIEKLKSAEEQITQLNDEIDAAN-KNMIKVKSNHKLKLKQMQKT-IDNFS 548 DE + I + AE +I QLN +++ K+ ++V ++ +L +Q++K +D+ Sbjct: 19 DEYNQFIATNPIGIILKAEFKIRQLNQTLESIQAKSQVEVTNSQQL-FQQLEKDYMDSKK 77 Query: 549 KVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENL 608 V NK+ + + ++L L K++ E K N +D + +S+++ + E Sbjct: 78 DVEQLNKQNITIKKDLQSL--KLSIERESKSNTLNRFID--ELQQEKSNLHSIIERKEKD 133 Query: 609 AETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADIS-QLQS-DQVCSEIK--SVHL 664 + + +S L + + ++E L+ K VE++ + Q+Q Q +E++ + L Sbjct: 134 LKEETETVSKLTERLNEFIKEKSDLKSKLITVENENSSNEFQIQRLKQEVNELRKQTTFL 193 Query: 665 EEQ----IDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDL 720 E+ + L KEL LKL E I L +++ + ++N L Sbjct: 194 EDSQKQTTNNLFNEIKELKSFNLELKLKNENQADEILKLNQINQNLKKQTSELEKKNQQL 253 Query: 721 TDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICR 780 ++++K++ EK+ ++ ++++ +Q + + QER E +++ ++R+ Sbjct: 254 NEEIKKITTEKV-----QMTSSFETELNSQKNLASLYQERS---EESSKKVTLLQNRLDA 305 Query: 781 LEESIAVM----EDRRYSLERKADQLGSYLQEKQKAYSEYTIQ-EDELVNRLAVLMDHDR 835 L+E+ + ED + +E D L + Q+ K + E+ + N+ + Sbjct: 306 LKEADKKLRKEHEDAYHKMEEAYDILEADYQKVIKEFDEFKQHTQANAQNQSFNGVGSSS 365 Query: 836 VVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTK 895 + + + I + + + + L L+ L DM Q Y+ L T +A +E + Sbjct: 366 DLSQMDIPILSDTVKERLSDATTLGSRDELRRELLDMIQRYDDL------TKIALNEKKE 419 Query: 896 YQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIE 955 KR +H + I+++ ++ L E N + + ++ ++ L Y++ Sbjct: 420 ------------KRYVQDHLSHILREVEKKAPLIHEQNREYQRLLKSQEKLLNSYQQLQS 467 Query: 956 YVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLN 1015 L ++ + L + +L K L+ + ++K+Q QS ++LN Sbjct: 468 QKETLSLKVTTISSENNKLKQEINDLQKQIRCLLQEALEKKQLQSQ----------SQLN 517 Query: 1016 ALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQL---- 1071 + + N +NN+ S S S L F T +E ++ Q + +Q+ Sbjct: 518 KSQFNGQQSTLFGNSVLNNS-TSTSSDDSIIPDSLITF-TNIEELQLRNQDLLRQIRILS 575 Query: 1072 LDSKQHNE---ELQILVREQDDQIKELKETKLTFEMNIPKTEG---MIISSTIEPMSDDA 1125 D + HNE +L++ ++E D +K +E + ++ K + S +P++ Sbjct: 576 QDIQSHNENDKKLEMALKEL-DHLKTARERQAEMIQSLVKQRDHYKNVSSPNSQPINQVG 634 Query: 1126 NNVDXXXXXXXXXXXXLKVQEEEEFIQERSV--LQEQSAKLNTELQECYTKIIQLETLNT 1183 NN + + + S+ ++ N + + + I+ N Sbjct: 635 NNNNNNSSSGGMMTLSDLSSSTNGMLNDSSMNGSINKNNNNNNSMNDSFNNSIKNNNNNN 694 Query: 1184 ELTGHD-VVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQH 1242 ++ +++ + Q + E L E + + + L+ + R EL + Sbjct: 695 NNNNNNSLLSSSTLIQQQQSNEILTQELEKIKQSYQLLQKDYEQVMKDRSISDKELLGKI 754 Query: 1243 LAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDK 1302 RE Q T L++Q+S +S+ + +Q ST N+ +EQ +L D Sbjct: 755 EQMRE---QNT--SLKIQISQIQSENTIFKERLQISTDSVKNQSQDLEQYRKKNQELMDA 809 Query: 1303 EEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQM 1362 +R+ Q+ ++ +Q+ RSE + + E + Sbjct: 810 V--VRH-QQSIENLNSQLS--RSEEFKSQAELRLSNIKGENQLIRASEERLIEMNKTLSL 864 Query: 1363 QEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHE 1422 ++ SI N+ ++ QL S R + + +LE T +++LK E+ Q+ + Sbjct: 865 EKLSIENLLDKVNQLNASK----ESSETELRRRIENDLTLLE-TQRIQLK-KELDQEKQQ 918 Query: 1423 YTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEI 1482 + T + R++ + EK + DL E +L + + + E +SE+ Sbjct: 919 HKETSIAMTHQINESRERFEKKEKELSDLK-ESIIKLKVSEQTLLQKITFLENQLNQSEL 977 Query: 1483 ERVKLIEEL-NVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEIT 1541 +IE + ++T S + + ++ N + K + Q + +++ EI Sbjct: 978 RYNTIIERTQSNQLTISPTTSSTLSTNNNNNNNQQQKLQQQQQQ-QQDNLDLSLAKSEIE 1036 Query: 1542 NLQNMVRASSSKIQKHVSFA----SDTKQGRDEQLDNTMNKELLDAVPRAELDLA 1592 +L++++ I + S A +D Q ++E + EL + + A+ +LA Sbjct: 1037 SLKDLLAQEKDNIVHYKSIAISNENDLSQLKEEYTKTKV--ELEERLKDAQAELA 1089 Score = 83.8 bits (198), Expect = 4e-14 Identities = 187/930 (20%), Positives = 388/930 (41%), Gaps = 81/930 (8%) Query: 212 EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIE-------SKDVRISSLEEANKLLEAAR 264 E KQ +Q+++ + + + LL IE S ++IS ++ N + + R Sbjct: 723 EKIKQSYQLLQKDYEQVMKDRSISDKELLGKIEQMREQNTSLKIQISQIQSENTIFKE-R 781 Query: 265 FEISLEHSK-LAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTE 323 +IS + K +Q+LEQ +QSIE + + EE S ++ Sbjct: 782 LQISTDSVKNQSQDLEQYRKKNQELMDAVVR-HQQSIENLNSQLSRSEEFKSQAELRLSN 840 Query: 324 LTKKIELLEHLNCQIRQTNKELE-NKLATMGTESKAVS-SPSKKGSPLISRKSGRNTASK 381 + + +L+ ++ + NK L KL+ K + SK+ S R+ N + Sbjct: 841 IKGENQLIRASEERLIEMNKTLSLEKLSIENLLDKVNQLNASKESSETELRRRIENDLTL 900 Query: 382 MKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXX 441 +++ QL E D +K+ +K + I + KE +S+ Sbjct: 901 LETQRIQLKKEL---DQEKQQHKETSIAMTHQINESRERFEKKEKELSD---LKESIIKL 954 Query: 442 XXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDL 501 + TL+ ++ Q + + N++ + L+ + N + Sbjct: 955 KVSEQTLLQKITFLENQLNQSELRYNTIIERTQSNQLT-ISPTTSSTLSTNNNNNNNQQ- 1012 Query: 502 IEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNK-EIVRL 560 +KL+ ++Q Q N ++ A + +K L Q + I ++ ++ SN+ ++ +L Sbjct: 1013 -QKLQQQQQQ-QQDNLDLSLAKSEIESLKD----LLAQEKDNIVHYKSIAISNENDLSQL 1066 Query: 561 TEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLE 620 EE + KV ELEE + Q L + E + K+ ++EN + + K I+ + Sbjct: 1067 KEE--YTKTKV-ELEERLKDAQAELAKSQE-TIKEQQI--KLEKLENFSSSHQKDINSII 1120 Query: 621 SQKFDLVQELHILQQKYDEV--EDKLA-DISQLQSDQVCSEI-----KSVHLE-EQIDAL 671 ++K ++ E L +K ++ + +LA D ++LQ Q+C + + V L E I L Sbjct: 1121 AEKDSILAEKQQLYEKIQQLTKDQQLALDEAKLQH-QLCRKATENYEREVVLHAEDIKVL 1179 Query: 672 SASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEK 731 + +L + + + ++ ++LE K+ + + Q Q+ +L ++L+ + Sbjct: 1180 PKLRDDLVEARKTINQMQIKIDSNSQELEQAKQSWIQQEQLLKQQIQELEERLKDLKHHN 1239 Query: 732 --ISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVME 789 + + IN + Q +I + + + ++ E E++ K + + E Sbjct: 1240 NLLHSQIENINQQTQ-QIDRYSQLSSSSSVGNGLVQVSEDEINNLKELVQVQAREQKITE 1298 Query: 790 DRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENK 849 + SL+++ +L S + QKA T + E + L R ++ L ++E N Sbjct: 1299 VKNESLQQENIRLKSTIAANQKAIETVTKKLQEEQENMRTLTVSTRKHQEVLAQLEQMN- 1357 Query: 850 ELQKKNQILLEEN--------QNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLR 901 L K++ I+L++ Q LQ L Q H L E +N+ LAE++ + + + Sbjct: 1358 -LFKESNIMLKDETRKLGAQVQELQEKLKQSQDHLLPLTE-SNKKLLAENQILHNEIEAQ 1415 Query: 902 DLE-----SNLKRITHEHQTL---IVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKN 953 +E ++++ +++Q++ + QK E + I N ++ + D K E +K Sbjct: 1416 KIEITNWSGKVQKLLNKYQSIDPEVHQKLLETNETTIRENQELTQQLEDLKKQLEDLKKQ 1475 Query: 954 IEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINK 1013 +E + Q ++ K + ++ + K LEL Q+++ S T+Q ++ Sbjct: 1476 LE---DNKKQYEDLKKHTKHWKEEAVKFKKDKLELDQSLTQQKELFST--TKQQLDSNTA 1530 Query: 1014 LNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLD 1073 N ++++E L +KI A + + + + A EE++ + KQL D Sbjct: 1531 TNEQTLKENQE---LRKKIQIANANKQANKQQIQQQQAN--------NEEIEALKKQLED 1579 Query: 1074 SKQHNEELQILVREQDDQIKELKETKLTFE 1103 +++ E+ + L + E K FE Sbjct: 1580 TRKLAEDYKKLADDYKKLTDEAKSKLKVFE 1609 Score = 71.7 bits (168), Expect = 2e-10 Identities = 153/857 (17%), Positives = 354/857 (41%), Gaps = 75/857 (8%) Query: 91 SESLANTLKQKEILMEKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNT 150 S+ L K+ + LM+ + ++++ + ++ + R +L ++ + Sbjct: 793 SQDLEQYRKKNQELMDAVVRHQQSIENLNSQLSRSEEFKSQAEL-----RLSNIKGENQL 847 Query: 151 IKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEA-KNKATTXXXXXXXXXXXXXXX 209 I+ + L + + + + +I +L +K+N+ + E+ + + Sbjct: 848 IRASEERLIEMNKTLSLEKLSIENLLDKVNQLNASKESSETELRRRIENDLTLLETQRIQ 907 Query: 210 XXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISL 269 ++ Q+ + +E IAM + + ++R E K+ +S L+E+ L+ + + Sbjct: 908 LKKELDQEKQQHKETSIAMTHQINESRERF----EKKEKELSDLKESIIKLKVSEQTLLQ 963 Query: 270 EHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIE 329 + + L +L Q + +I P+ + N + ++ + Sbjct: 964 KITFLENQLNQSELRYNTIIERTQS-NQLTISPTTSSTLSTNNNNN---NNQQQKLQQQQ 1019 Query: 330 LLEHLNCQIRQTNKELENKLATMGTESKAV---SSPSKKGSPLISRKSGRNTASK--MKS 384 + N + E+E+ + E + S + +S+ T +K ++ Sbjct: 1020 QQQQDNLDLSLAKSEIESLKDLLAQEKDNIVHYKSIAISNENDLSQLKEEYTKTKVELEE 1079 Query: 385 PWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDL----VDKEYVISEKDTXXXXXXX 440 +E K + ++ KLE S KD+ +K+ +++EK Sbjct: 1080 RLKDAQAELAKSQETIKEQQIKLEKLENFSSSHQKDINSIIAEKDSILAEKQQLYEKIQQ 1139 Query: 441 XXXGKDTLIAQLQLEHQQHMEGPSLIH--VGTNTEDVNEIAKVQEQL---KQELND-EIK 494 + + + +L+HQ + V + ED+ + K+++ L ++ +N +IK Sbjct: 1140 LTKDQQLALDEAKLQHQLCRKATENYEREVVLHAEDIKVLPKLRDDLVEARKTINQMQIK 1199 Query: 495 -DVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKL------KLKQMQKTIDNF 547 D N ++L + +S +Q L +I + + +K ++ L + Q + ID + Sbjct: 1200 IDSNSQELEQAKQSWIQQEQLLKQQIQELEERLKDLKHHNNLLHSQIENINQQTQQIDRY 1259 Query: 548 SKVSDSNKE---IVRLTE-ELHHLS---------QKVAELEEE---KGNLQLHLVDYDSG 591 S++S S+ +V+++E E+++L QK+ E++ E + N++L + Sbjct: 1260 SQLSSSSSVGNGLVQVSEDEINNLKELVQVQAREQKITEVKNESLQQENIRLKSTIAANQ 1319 Query: 592 RMIESDVYKKMIEMENL----AETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADI 647 + IE+ K E EN+ TR L + ++ +L +E +I+ + DE A + Sbjct: 1320 KAIETVTKKLQEEQENMRTLTVSTRKHQEVLAQLEQMNLFKESNIMLK--DETRKLGAQV 1377 Query: 648 SQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIM 707 +LQ S+ + L E L A + L IE K++ G ++ L N + I Sbjct: 1378 QELQEKLKQSQDHLLPLTESNKKLLAENQILHNEIEAQKIEITNWSGKVQKLLNKYQSID 1437 Query: 708 NKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDL--YIE 765 ++ + E + T + + +++ +L ++ E K Q + D K Q DL + + Sbjct: 1438 PEVHQKLLETNETTIRENQELTQQLEDLKKQL---EDLKKQLE---DNKKQYEDLKKHTK 1491 Query: 766 NIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVN 825 + + E K+K L++S+ ++ + +++ D A +E T++E++ + Sbjct: 1492 HWKEEAVKFKKDKLELDQSLTQQKELFSTTKQQLDS--------NTATNEQTLKENQELR 1543 Query: 826 RLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANR 885 + + + ++ KQ ++ + N E + + LE+ + L + Y L ++A + Sbjct: 1544 KKIQIANANKQANKQQIQQQQANNEEIEALKKQLEDTRKLAEDYKKLADDYKKLTDEA-K 1602 Query: 886 TDLAESESTKYQTQLRD 902 + L ES K + L + Sbjct: 1603 SKLKVFESMKKASALNN 1619 >UniRef50_Q22AQ6 Cluster: Putative uncharacterized protein; n=1; Tetrahymena thermophila SB210|Rep: Putative uncharacterized protein - Tetrahymena thermophila SB210 Length = 1845 Score = 123 bits (296), Expect = 5e-26 Identities = 181/872 (20%), Positives = 401/872 (45%), Gaps = 105/872 (12%) Query: 475 VNEIAKVQEQLKQELNDEIKDVNVKD--LIEKLKSAEEQITQLNDEIDAANKNMIKVKSN 532 V E + Q +++L DE+ + + K+ + E+ ++ + ++ LN++I+ M+K+ + Sbjct: 486 VREAREAQLNAEKQLTDELTNRSQKETQISERYETQKTELILLNNKIE-----MLKLDAE 540 Query: 533 HKLKLK-QMQKTIDNFSKVSDSN-KEI-VRLTEELHHLSQKVAELEEEKGNLQLHLVDYD 589 K K ++K +DN + KE+ + + +++ L + LE+E + +L+ + Sbjct: 541 RICKEKYNLEKLVDNLKVEHEEKLKEVKMEMKKKIKELKKTNQNLEKEISMKENNLLQIE 600 Query: 590 SGRMIESD----VYKKMIEMENLAETRLKAIS-----LLESQ-KFDLV-QELHILQQKYD 638 + +I S + K++E+++L E +++ + L E Q K+DL+ QEL +Q ++ Sbjct: 601 NEGVILSKNTNALSDKVLELQSLLEKKIEEVREKDKVLQEEQNKYDLLSQELQTQRQSFE 660 Query: 639 EVEDKLADIS-----QLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLY 693 ++L + + QL + + SV E L K+E I + L Sbjct: 661 VTINQLQNSNKSIQEQLLRKNILLDSASVSFEVNQKCLIKEKEEALEKIIKCNEEISHLK 720 Query: 694 GTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQ--SKIQTQF 751 T+++ + ED+ K+ + +N ++ + EK+ +E + ++ + ++ ++I Sbjct: 721 KTLEEQQFKNEDLQEKINDLRLQNENMLLQAEKLRSENLEQMRIFQDTQKSLNNRIDQLI 780 Query: 752 GIDAKIQERDLYIENIESELSKYKSRICRLE-ESIAVMEDRRYSLERKADQLGSYLQEKQ 810 + K+Q+ +L N+ K+ +L+ E + +++D ++ K L EK Sbjct: 781 SENNKLQQTELL--NLNERCDKFNLMFQQLQQEKLQLIQDNSIIVQDKIT-----LSEKV 833 Query: 811 KAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLS 870 + +Q++ ++ L+ + ++D K+++E+++E +L + L +EN L+ + Sbjct: 834 RE-----LQQNN-IDLLSKIHNYDNQKNKEIVELKYELDQLINQKDKLKQENHLLEQEIQ 887 Query: 871 DMQQHYNALVEKANRTDLAESESTKYQTQLRDL--ESNLK-RITHEHQTLIVQKKKEIED 927 + + + N+ E+ N + E ++Q QL L ES LK H+ + LI+ +K +I+ Sbjct: 888 EYKNNINSYKEQINSFIV---EINQFQLQLDTLKQESRLKTEQIHQQENLILNQKNQIDT 944 Query: 928 LEIEFNTQIESAIRDKKVLNEKYEKNIEY-VTQLEAQL----QEYKNNIENLNMNVEELN 982 L +K L+++ E+ I+Y + +LE + Q+Y+N I+NL +N E+L Sbjct: 945 LV------------EKSYLDQESERLIDYKLKELEDEKIACNQKYENAIQNLRINEEQLR 992 Query: 983 KMNLELIDKHVQKQ--------QTQSPDYTEQYIN----EINKLNALLKQKDEEIIALNQ 1030 ++++L K Q + TQ + IN +INKL+A LK+ ++ + A+ Sbjct: 993 SLSIQLNQKSEQVKILEDYKNVLTQEKEQQLVEINKCHLQINKLSAELKEAEQSLQAVQD 1052 Query: 1031 KINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDD 1090 K + QVS S + Q++ +L ++ + + +QL + E ++ E Sbjct: 1053 KCKDLQVSLNSASDQIFNIKQQYSQELIEKDQMILQCKEQLRYQCMNQIEQSQVLEEMTS 1112 Query: 1091 QIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEF 1150 +I++ K + + N+ K + I+ + D N + +Q++ + Sbjct: 1113 EIEKQKNLEQQVQ-NLRKENEKLELEQIKLLKD--NEI----------LRLHLIQKQPDN 1159 Query: 1151 IQERSVLQEQS---AKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLN 1207 Q +L+E + + + E+Q K+ Q + + + T N+ QI K+ + Sbjct: 1160 CQIELILEEHNQILTEYHEEIQRLKDKLQQKQQILEKFT-----NKIQIQ--SDKIAENE 1212 Query: 1208 TENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESK 1267 E NL S +A + + +++ ++ ++ +Q+ Q++ H L +S Sbjct: 1213 KEISNLQSFIANGKKHYENLIEEYQLKMDQMQQQN-TQQQIVLNNQIHLLMQDKQQMKSH 1271 Query: 1268 YEQLLDSVQSSTQEETNKIVTMEQVTSLQNKL 1299 LD +Q + T + M Q+ + +L Sbjct: 1272 ----LDQIQKEMSDITQLSLKMSQIPQTRTQL 1299 Score = 122 bits (293), Expect = 1e-25 Identities = 219/1040 (21%), Positives = 454/1040 (43%), Gaps = 107/1040 (10%) Query: 297 KQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTES 356 K IE E+ ++ K E+ + + ++LE N QI+Q N + E + Sbjct: 351 KMEIELLKEQNDALKSKVD-ELTLLVNDKEMQKILEEKNFQIKQVNADYEQLAEKYASIE 409 Query: 357 KAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQS 416 KA + L + ++ +SP + L Q+ +KK+ E E IQS Sbjct: 410 KAYDLMHIEYDSLNQKYLELQSS---RSP-RDTENVDLVQELEKKVLYMEEKMREDEIQS 465 Query: 417 LNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVN 476 NK K V+ ++++ ++ AQL E Q E L + ++ Sbjct: 466 -NK---MKMVVLKQEESISILENLVREARE---AQLNAEKQLTDE---LTNRSQKETQIS 515 Query: 477 EIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIK-VKSNHKL 535 E + Q+ LN++I+ + + E++ + + +L D + ++ +K VK K Sbjct: 516 ERYETQKTELILLNNKIEMLKLD--AERICKEKYNLEKLVDNLKVEHEEKLKEVKMEMKK 573 Query: 536 KLKQMQKTIDNFSK-VSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMI 594 K+K+++KT N K +S ++++ E LS+ L ++ LQ L++ + Sbjct: 574 KIKELKKTNQNLEKEISMKENNLLQIENEGVILSKNTNALSDKVLELQ-SLLEKKIEEVR 632 Query: 595 ESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQ 654 E D K+++ E L + Q F++ ++ LQ +++ QL Sbjct: 633 EKD---KVLQEEQNKYDLLSQELQTQRQSFEVT--INQLQNSNKSIQE------QLLRKN 681 Query: 655 VCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYI 714 + + SV E L K+E I + L T+++ + ED+ K+ + Sbjct: 682 ILLDSASVSFEVNQKCLIKEKEEALEKIIKCNEEISHLKKTLEEQQFKNEDLQEKINDLR 741 Query: 715 QENMDLTDKLEKMSAEKISE--LLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELS 772 +N ++ + EK+ +E + + + ++I + K+Q+ +L N+ Sbjct: 742 LQNENMLLQAEKLRSENLEQMRIFQDTQKSLNNRIDQLISENNKLQQTELL--NLNERCD 799 Query: 773 KYKSRICRL-EESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLM 831 K+ +L +E + +++D ++ K L EK + +Q++ ++ L+ + Sbjct: 800 KFNLMFQQLQQEKLQLIQDNSIIVQDKIT-----LSEKVR-----ELQQNN-IDLLSKIH 848 Query: 832 DHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAES 891 ++D K+++E+++E +L + L +EN L+ + + + + N+ E+ N + + E Sbjct: 849 NYDNQKNKEIVELKYELDQLINQKDKLKQENHLLEQEIQEYKNNINSYKEQIN-SFIVEI 907 Query: 892 ESTKYQTQLRDLESNLK-RITHEHQTLIVQKKKEIEDL-EIEFNTQIESAIRDKKVLNEK 949 + Q ES LK H+ + LI+ +K +I+ L E + Q + D K L E Sbjct: 908 NQFQLQLDTLKQESRLKTEQIHQQENLILNQKNQIDTLVEKSYLDQESERLIDYK-LKEL 966 Query: 950 YEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYIN 1009 ++ I A Q+Y+N I+NL +N E+L ++++L Q+++ E Y Sbjct: 967 EDEKI-------ACNQKYENAIQNLRINEEQLRSLSIQL------NQKSEQVKILEDY-- 1011 Query: 1010 EINKLNALLKQKDEEIIALNQKINNAQVSYMSM-VSDYESKLAQFTTKLENMEEEMQRVS 1068 N L ++K+++++ +N+ + Q++ +S + + E L K ++++ + S Sbjct: 1012 ----KNVLTQEKEQQLVEINK--CHLQINKLSAELKEAEQSLQAVQDKCKDLQVSLNSAS 1065 Query: 1069 KQLLDSKQHNEELQILVREQDDQIKELKETKLTFE-MNIPKTEGMIISSTIEPMSDDANN 1127 Q+ + KQ + I E+D I + KE +L ++ MN + ++ T E + N Sbjct: 1066 DQIFNIKQQYSQELI---EKDQMILQCKE-QLRYQCMNQIEQSQVLEEMTSE--IEKQKN 1119 Query: 1128 VDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTG 1187 ++ L++ E+ + +++ +L+ + + C ++I LE N LT Sbjct: 1120 LEQQVQNLRKENEKLEL-EQIKLLKDNEILRLH--LIQKQPDNCQIELI-LEEHNQILTE 1175 Query: 1188 HDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQRE 1247 + E+I +LK KL+Q +L S + + EI+ L + +A + Sbjct: 1176 Y----HEEIQRLKDKLQQ----KQQILEKFTNKIQIQSDKIAENEKEISNL-QSFIANGK 1226 Query: 1248 ADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLR 1307 ++ E ++ K +Q+ Q +TQ++ IV Q+ L Q + HL Sbjct: 1227 KHYENLIEE-------YQLKMDQM---QQQNTQQQ---IVLNNQIHLLMQDKQQMKSHLD 1273 Query: 1308 NLQEKYADVINQIEILRSEI 1327 +Q++ +D I Q+ + S+I Sbjct: 1274 QIQKEMSD-ITQLSLKMSQI 1292 Score = 114 bits (275), Expect = 2e-23 Identities = 207/1038 (19%), Positives = 444/1038 (42%), Gaps = 111/1038 (10%) Query: 557 IVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEME-NLAETRLKA 615 I LT E SQ++ E E + + + +G++ + V KMI + ++ LK Sbjct: 185 ITSLTFEKKPASQQLKENNENCLGVVIQNLKQYAGQLGPTLVSNKMIPQQIPFIQSPLKT 244 Query: 616 ISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQS-DQVCSEI--KSVHLEEQIDALS 672 +K D + + IL Q + +++ + QL + DQ +I K E+ ++ Sbjct: 245 SLQSSGKKTDKIVNVQILSQNQN-IQNAVLQNQQLNAQDQAALKIAEKEAQKEKNLNLFK 303 Query: 673 AS----------KKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTD 722 S + EL + LK DK+ +YG+ L D+E ++ +++ I+ + D Sbjct: 304 ESSIKFITNTDLEAELKDLAHLLKRDKD-MYGSNIMLTTDREQVIPEMKMEIELLKEQND 362 Query: 723 KLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLE 782 L+ K+ EL +N +E KI ++E++ I+ + ++ + + +E Sbjct: 363 ALKS----KVDELTLLVNDKEMQKI---------LEEKNFQIKQVNADYEQLAEKYASIE 409 Query: 783 ESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLA--VLMDHDRVVEKQ 840 ++ +M SL +K YL E Q + S + +LV L VL +++ E + Sbjct: 410 KAYDLMHIEYDSLNQK------YL-ELQSSRSPRDTENVDLVQELEKKVLYMEEKMREDE 462 Query: 841 LLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQL 900 + + + L+++ I + EN + + + E NR+ S +Y+TQ Sbjct: 463 IQSNKMKMVVLKQEESISILENLVREAREAQLNAEKQLTDELTNRSQKETQISERYETQK 522 Query: 901 RDLE--SNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVT 958 +L +N + I ++K +E L + E +++ K+ +K K ++ Sbjct: 523 TELILLNNKIEMLKLDAERICKEKYNLEKLVDNLKVEHEEKLKEVKMEMKKKIKELKKTN 582 Query: 959 Q-LEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNAL 1017 Q LE ++ +NN+ + L+K L DK ++ Q E+ I E+ + + + Sbjct: 583 QNLEKEISMKENNLLQIENEGVILSKNTNALSDKVLELQSL-----LEKKIEEVREKDKV 637 Query: 1018 LKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQH 1077 L+++ + L+Q++ + S+ E + Q ++++E++ R LLDS Sbjct: 638 LQEEQNKYDLLSQELQTQRQSF-------EVTINQLQNSNKSIQEQLLR-KNILLDSASV 689 Query: 1078 NEEL--QILVREQDDQIK-------ELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNV 1128 + E+ + L++E+++ ++ E+ K T E K E + + ++ + Sbjct: 690 SFEVNQKCLIKEKEEALEKIIKCNEEISHLKKTLEEQQFKNEDLQEKINDLRLQNENMLL 749 Query: 1129 DXXXXXXXXXXXXLKVQEEEEFIQER--SVLQEQSAKLNTEL----QECYTKIIQLETLN 1182 Q+ ++ + R ++ E + TEL + C + + L Sbjct: 750 QAEKLRSENLEQMRIFQDTQKSLNNRIDQLISENNKLQQTELLNLNERCDKFNLMFQQLQ 809 Query: 1183 TE----LTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAEL 1238 E + + ++ Q++I L K+ +L N +LLS + + + + + +E+ +L Sbjct: 810 QEKLQLIQDNSIIVQDKIT-LSEKVRELQQNNIDLLSKIHNYDNQKNKEIVELKYELDQL 868 Query: 1239 WKQ--------HLAQREA-DFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTM 1289 Q HL ++E +++ + + Q+++F + Q +Q T ++ +++ T Sbjct: 869 INQKDKLKQENHLLEQEIQEYKNNINSYKEQINSFIVEINQF--QLQLDTLKQESRLKT- 925 Query: 1290 EQVTSLQNKLQDKEEHLRNLQEK-YADVINQ--IEILRSEIEDEKVAFXXXXXXXXXXXX 1346 EQ+ +N + +++ + L EK Y D ++ I+ E+EDEK+A Sbjct: 926 EQIHQQENLILNQKNQIDTLVEKSYLDQESERLIDYKLKELEDEKIACNQKYENAIQNLR 985 Query: 1347 XXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELT 1406 LR+ + Q EQ + + +N L + ++N A++ E Sbjct: 986 INEEQLRSLSIQLNQKSEQVKILEDYKNV-LTQEKEQQLVEINKCHLQINKLSAELKEAE 1044 Query: 1407 HQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKM 1466 L+ + K + ++L +D+ N++QQ Y + + E + IL+ K Sbjct: 1045 QSLQA----VQDKCKDLQVSLNSASDQIFNIKQQ---YSQELI------EKDQMILQCK- 1090 Query: 1467 HENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTAL 1526 Y+ M ++IE+ +++EE+ +I + +L +QV L K E E + +++ Sbjct: 1091 --EQLRYQCM---NQIEQSQVLEEMTSEIEKQKNLEQQVQNLRK--ENEKLELEQIKLLK 1143 Query: 1527 ENQEIEIVTLNDEITNLQ 1544 +N+ + + + + N Q Sbjct: 1144 DNEILRLHLIQKQPDNCQ 1161 Score = 96.7 bits (230), Expect = 5e-18 Identities = 166/776 (21%), Positives = 355/776 (45%), Gaps = 72/776 (9%) Query: 392 ETLNQDTDKKIN--KNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDT-L 448 + L + ++K+ K E+ K ++ N++L +KE + E + K+T Sbjct: 554 DNLKVEHEEKLKEVKMEMKKKIKELKKTNQNL-EKEISMKENNLLQIENEGVILSKNTNA 612 Query: 449 IAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIK--DVNVKDLIEKLK 506 ++ LE Q +E + V + + E + L QEL + + +V + L K Sbjct: 613 LSDKVLELQSLLE-KKIEEVREKDKVLQEEQNKYDLLSQELQTQRQSFEVTINQLQNSNK 671 Query: 507 SAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHH 566 S +EQ+ + N +D+A+ + + N K +K+ ++ ++ K+ N+EI L + L Sbjct: 672 SIQEQLLRKNILLDSAS---VSFEVNQKCLIKEKEEALE---KIIKCNEEISHLKKTLEE 725 Query: 567 LSQKVAELEEEKGNLQLHLVDYD-SGRMIESDVYKKMIEMENLAETRLKAISLLESQKFD 625 K +L+E+ +L+L + + S+ ++M ++ ++ I L S+ Sbjct: 726 QQFKNEDLQEKINDLRLQNENMLLQAEKLRSENLEQMRIFQDTQKSLNNRIDQLISENNK 785 Query: 626 LVQ-ELHILQQKYDEVEDKLADISQ-----LQSDQVCSEIKSVHLEEQIDALSASKKELA 679 L Q EL L ++ D+ + Q +Q + + + K + L E++ L + +L Sbjct: 786 LQQTELLNLNERCDKFNLMFQQLQQEKLQLIQDNSIIVQDK-ITLSEKVRELQQNNIDLL 844 Query: 680 LVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKI 739 I N K + I +L+ + + ++N+ QEN L ++++ I+ +I Sbjct: 845 SKIHNYDNQKNK---EIVELKYELDQLINQKDKLKQENHLLEQEIQEYK-NNINSYKEQI 900 Query: 740 NHEEQSKIQTQFGIDAKIQERDLYIENI---ESELSKYKSRICRL-EESIAVMEDRR--- 792 N Q Q +D QE L E I E+ + K++I L E+S E R Sbjct: 901 NSFIVEINQFQLQLDTLKQESRLKTEQIHQQENLILNQKNQIDTLVEKSYLDQESERLID 960 Query: 793 YSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQ 852 Y L+ D+ + Q+ + A I E++L R + + + + ++LE +++N Q Sbjct: 961 YKLKELEDEKIACNQKYENAIQNLRINEEQL--RSLSIQLNQKSEQVKILE-DYKNVLTQ 1017 Query: 853 KKNQILLEENQ-NLQIS-----LSDMQQHYNALVEKANRTDLAESEST--------KYQT 898 +K Q L+E N+ +LQI+ L + +Q A+ +K ++ + ++ +Y Sbjct: 1018 EKEQQLVEINKCHLQINKLSAELKEAEQSLQAVQDKCKDLQVSLNSASDQIFNIKQQYSQ 1077 Query: 899 QLRDLESNLKRITHE--HQTLI-VQKKKEIEDL--EIEFNTQIESAIRDKKVLNEKYE-K 952 +L + + + + + +Q + +++ + +E++ EIE +E +++ + NEK E + Sbjct: 1078 ELIEKDQMILQCKEQLRYQCMNQIEQSQVLEEMTSEIEKQKNLEQQVQNLRKENEKLELE 1137 Query: 953 NIEYVTQLEAQ----LQEYKNNIENLNMNVEELNKMNLELIDK--HVQKQQTQSPDYTEQ 1006 I+ + E +Q+ +N + + + +EE N++ E ++ ++ + Q E+ Sbjct: 1138 QIKLLKDNEILRLHLIQKQPDNCQ-IELILEEHNQILTEYHEEIQRLKDKLQQKQQILEK 1196 Query: 1007 YINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQR 1066 + N+I + + + ++EI L I N + Y +++ +Y+ K+ Q + + + Sbjct: 1197 FTNKIQIQSDKIAENEKEISNLQSFIANGKKHYENLIEEYQLKMDQMQQQNTQQQIVLNN 1256 Query: 1067 VSKQLLDSKQHNEELQILVREQDDQI-KELKE-TKLTFEMN-IPKTEGMIISSTIE 1119 L+ KQ ++ DQI KE+ + T+L+ +M+ IP+T + S+I+ Sbjct: 1257 QIHLLMQDKQQ-------MKSHLDQIQKEMSDITQLSLKMSQIPQTRTQLCESSIK 1305 Score = 84.2 bits (199), Expect = 3e-14 Identities = 158/867 (18%), Positives = 369/867 (42%), Gaps = 67/867 (7%) Query: 153 EKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXE 212 E + + L+ K+ ME + + + + N+ ++ + ++ + + Sbjct: 439 ENVDLVQELEKKVLYMEEKMREDEIQSNKMKMVVLKQEESISILENLVREAREAQLNAEK 498 Query: 213 DTKQQMTKMQENFIAMEAEWKDEKQRLL---KDIESKDVRISSLEEANKLLEAARFEISL 269 ++T + + ++ +K L+ IE + + + LE + + Sbjct: 499 QLTDELTNRSQKETQISERYETQKTELILLNNKIEMLKLDAERICKEKYNLEKLVDNLKV 558 Query: 270 EHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKI- 328 EH + +E++ ++ I +IE +G + N L+ K+ Sbjct: 559 EHEEKLKEVKMEMKKKIKELKKTNQNLEKEISMKENNLLQIENEGVILSKNTNALSDKVL 618 Query: 329 ---ELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISR--KSGRNTASKMK 383 LLE ++R+ +K L+ + S+ + + + I++ S ++ ++ Sbjct: 619 ELQSLLEKKIEEVREKDKVLQEEQNKYDLLSQELQTQRQSFEVTINQLQNSNKSIQEQLL 678 Query: 384 SPWSQLSSETLNQDTDKK-INKNEIAKLEMVIQSLNKDLVDKEYVISEK----DTXXXXX 438 L S +++ + ++K + K + LE +I+ N+++ + + E+ + Sbjct: 679 RKNILLDSASVSFEVNQKCLIKEKEEALEKIIKC-NEEISHLKKTLEEQQFKNEDLQEKI 737 Query: 439 XXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNV 498 + ++ Q + +++E + T N I ++ + + E+ +N+ Sbjct: 738 NDLRLQNENMLLQAEKLRSENLEQMRIFQ-DTQKSLNNRIDQLISENNKLQQTEL--LNL 794 Query: 499 KDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKT-IDNFSKV----SDS 553 + +K +Q+ Q ++ N +++ K K++++Q+ ID SK+ + Sbjct: 795 NERCDKFNLMFQQLQQEKLQLIQDNSIIVQDKITLSEKVRELQQNNIDLLSKIHNYDNQK 854 Query: 554 NKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSG-RMIESDVYKKMIEMEN--LAE 610 NKEIV L EL L + +L++E L+ + +Y + + + ++E+ L Sbjct: 855 NKEIVELKYELDQLINQKDKLKQENHLLEQEIQEYKNNINSYKEQINSFIVEINQFQLQL 914 Query: 611 TRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDA 670 LK S L++++ + L IL QK +++ D L + S L DQ + L+E D Sbjct: 915 DTLKQESRLKTEQIHQQENL-ILNQK-NQI-DTLVEKSYL--DQESERLIDYKLKELEDE 969 Query: 671 LSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAE 730 A ++ I+NL++++EQL L N K + + L++Y +N+ LT + E+ E Sbjct: 970 KIACNQKYENAIQNLRINEEQLRSLSIQL-NQKSEQVKILEDY--KNV-LTQEKEQQLVE 1025 Query: 731 ------KISELLAKINHEEQSKIQTQF---GIDAKIQERDLYIENIES----ELSKYKSR 777 +I++L A++ EQS Q + + I NI+ EL + Sbjct: 1026 INKCHLQINKLSAELKEAEQSLQAVQDKCKDLQVSLNSASDQIFNIKQQYSQELIEKDQM 1085 Query: 778 ICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTI----QEDELVNRLAVLMDH 833 I + +E + + + +++ S + EKQK + + ++L L+ Sbjct: 1086 ILQCKEQLRYQCMNQIEQSQVLEEMTSEI-EKQKNLEQQVQNLRKENEKLELEQIKLLKD 1144 Query: 834 DRVVEKQLLEIEHENKE----LQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLA 889 + ++ L++ + +N + L++ NQIL E ++ +Q +QQ L + N+ + Sbjct: 1145 NEILRLHLIQKQPDNCQIELILEEHNQILTEYHEEIQRLKDKLQQKQQILEKFTNKIQIQ 1204 Query: 890 ESESTKYQTQLRDLES-------NLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRD 942 + + + ++ +L+S + + + E+Q + Q +++ +I N QI ++D Sbjct: 1205 SDKIAENEKEISNLQSFIANGKKHYENLIEEYQLKMDQMQQQNTQQQIVLNNQIHLLMQD 1264 Query: 943 KKVLN---EKYEKNIEYVTQLEAQLQE 966 K+ + ++ +K + +TQL ++ + Sbjct: 1265 KQQMKSHLDQIQKEMSDITQLSLKMSQ 1291 Score = 57.2 bits (132), Expect = 3e-06 Identities = 129/687 (18%), Positives = 283/687 (41%), Gaps = 54/687 (7%) Query: 151 IKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXX 210 ++EKD L Q K ++ + ++ ++ NK+ Sbjct: 631 VREKDKVLQEEQNKYDLLSQELQTQRQSFEVTINQLQNSNKSIQEQLLRKNILLDSASVS 690 Query: 211 XEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLE 270 E ++ + K +E + + +E L K +E + + L+E L + L+ Sbjct: 691 FEVNQKCLIKEKEEALEKIIKCNEEISHLKKTLEEQQFKNEDLQEKINDLRLQNENMLLQ 750 Query: 271 HSKLAQE-LEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIE 329 KL E LEQ I+ E ++++ E+ N+ E K Sbjct: 751 AEKLRSENLEQMRIFQDTQKS-----LNNRIDQLISENNKLQQ---TELLNLNERCDKFN 802 Query: 330 LLEHLNCQIRQTNKEL--ENKLATMG--TESKAVSSPSKKGSPLISRKSGRNTASKMKSP 385 L+ Q++Q +L +N + T S+ V + L+S+ + + Sbjct: 803 LMFQ---QLQQEKLQLIQDNSIIVQDKITLSEKVRELQQNNIDLLSKIHNYDNQKNKEIV 859 Query: 386 WSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVD-KEYVISEKDTXXXXXXXXXXG 444 + + L DK +N + LE IQ ++ KE + ++ Sbjct: 860 ELKYELDQLINQKDKLKQENHL--LEQEIQEYKNNINSYKEQI----NSFIVEINQFQLQ 913 Query: 445 KDTLIAQLQLEHQQHMEGPSLIHVGTNTEDV--------NEIAKVQEQLKQELNDEIKDV 496 DTL + +L+ +Q + +LI N D E ++ + +EL DE Sbjct: 914 LDTLKQESRLKTEQIHQQENLILNQKNQIDTLVEKSYLDQESERLIDYKLKELEDEKIAC 973 Query: 497 NVK--DLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSN 554 N K + I+ L+ EEQ+ L+ +++ ++ +K+ ++K L Q ++ +++ + Sbjct: 974 NQKYENAIQNLRINEEQLRSLSIQLNQKSE-QVKILEDYKNVLTQEKE--QQLVEINKCH 1030 Query: 555 KEIVRLTEELHHLSQKVAELEEEKGNLQLHLVD-YDSGRMIESDVYKKMIEMENLAETRL 613 +I +L+ EL Q + ++++ +LQ+ L D I+ +++IE + + L Sbjct: 1031 LQINKLSAELKEAEQSLQAVQDKCKDLQVSLNSASDQIFNIKQQYSQELIEKDQMI---L 1087 Query: 614 KAISLLESQKFDLVQELHILQQKYDEVEDKL---ADISQLQSDQVCSEIKSVHLEEQIDA 670 + L Q + +++ +L++ E+E + + L+ + E++ + L + + Sbjct: 1088 QCKEQLRYQCMNQIEQSQVLEEMTSEIEKQKNLEQQVQNLRKENEKLELEQIKLLKDNEI 1147 Query: 671 LSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAE 730 L + ++L E+ + + + + + +KLQ Q T+K++ + ++ Sbjct: 1148 LRLHLIQKQPDNCQIELILEEHNQILTEYHEEIQRLKDKLQQKQQILEKFTNKIQ-IQSD 1206 Query: 731 KISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMED 790 KI+E N +E S +Q+ F + K +L IE + ++ + + + ++ I V+ + Sbjct: 1207 KIAE-----NEKEISNLQS-FIANGKKHYENL-IEEYQLKMDQMQQQ--NTQQQI-VLNN 1256 Query: 791 RRYSLERKADQLGSYLQEKQKAYSEYT 817 + + L + Q+ S+L + QK S+ T Sbjct: 1257 QIHLLMQDKQQMKSHLDQIQKEMSDIT 1283 >UniRef50_A2EJ44 Cluster: Viral A-type inclusion protein, putative; n=1; Trichomonas vaginalis G3|Rep: Viral A-type inclusion protein, putative - Trichomonas vaginalis G3 Length = 676 Score = 123 bits (296), Expect = 5e-26 Identities = 142/705 (20%), Positives = 323/705 (45%), Gaps = 59/705 (8%) Query: 616 ISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASK 675 + L++ + +L Q+L + + D +++ + +S + +++ ++++ + +E+I+ L+ Sbjct: 12 LELMDQENTELKQKLDEITSERDNLKNSNSQLSA-EIEELKKKVETENNDEEINELTEEI 70 Query: 676 KELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISEL 735 + L+ +E K E L K++E K+D NK++ + E+ + E ISEL Sbjct: 71 ESLSAELEQEKTKNENLN---KEIETLKQDYENKIKE-LSESSKSKESGHSDDGEVISEL 126 Query: 736 LAKINH--EEQSKIQTQ-FGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRR 792 +IN EE K ++ ++A +QE + + + E + + +I L E+I +++ Sbjct: 127 EDEINRLKEELDKSKSHNTELEAILQENEEKLNSKSQESTDSEQKIKELTETIQSLQNSN 186 Query: 793 YSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQ 852 ++ D L + +++ +K ++ ++D++ L+ + + ++ ++ + EN+E+Q Sbjct: 187 TEMQNSQDDLKNQIEKLKKIINQ---KDDDISKHLSDI----QALQTEIENSDKENQEIQ 239 Query: 853 KKNQILLEE----NQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLK 908 ++ Q L++E NQ L L + Q++Y L ++N + ++E + +L ES++ Sbjct: 240 QEKQKLIDELNEKNQQLTDQLKESQENYEKLKSESNDEKVGQNELNE---KLLAAESDIN 296 Query: 909 RITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYK 968 + + I ++I E+N+QI +KV +KY+ + + +T +A+L + Sbjct: 297 DLKSQ----IESNNQQIS----EYNSQISEL--QQKV--DKYKVSNDQLTASQAELSQ-- 342 Query: 969 NNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIAL 1028 +E+ +E+L N E + + Q+ + E + +++ L++ + + + +AL Sbjct: 343 -KLEDSTSEIEKLKSENNEK-SQAITDLQSSNNTNNENLLKQLDLLSSKISELENSSLAL 400 Query: 1029 NQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQL--------LDSKQHNEE 1080 + N + + SKL + L N + ++Q+ + ++ L + + Sbjct: 401 KSE-NKTLTEQIGSLDHENSKLKRDFEVLSNEKSKLQKENDKVKADIEQLSLSNSDEIGK 459 Query: 1081 LQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXX 1140 L L++ +D+QI EL++ N K E I+ +++ N + Sbjct: 460 LNDLIQSKDNQISELQKENDENMTNKAKLE-----EEIKRSAEEIENKEKEIESLNSQLE 514 Query: 1141 XLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLK 1200 LK EE ++ L E +N ++ + + I + E + E Q +I+ L Sbjct: 515 NLKKSMEESEEGDKKTLVE----MNQKISDLNSMISENEKIIEEKQSEIDQKQSEIDSLS 570 Query: 1201 SKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELW---KQHLAQREADFQKTEHEL 1257 + + L + D + + +S + S + E+ EL +Q +Q E +K E+ Sbjct: 571 HENQDLQQKLDEMKQNYEDEKSKLISEKESVDHELNELKNKSEQEKSQNEEKIEKLNKEI 630 Query: 1258 RVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDK 1302 E +Q D + QE+ N+I + + TS + K + K Sbjct: 631 EEINKQNEELSKQNNDEFSNLIQEKNNEINKLNEETSRKRKKKKK 675 Score = 120 bits (290), Expect = 3e-25 Identities = 153/702 (21%), Positives = 298/702 (42%), Gaps = 54/702 (7%) Query: 834 DRVVE--KQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAES 891 D + E +QL ++ EN EL++K + E NL+ S S + L +K T+ + Sbjct: 3 DEIAELTEQLELMDQENTELKQKLDEITSERDNLKNSNSQLSAEIEELKKKVE-TENNDE 61 Query: 892 ESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYE 951 E + ++ L + L++ +++ L KEIE L+ ++ +I+ K + Sbjct: 62 EINELTEEIESLSAELEQEKTKNENL----NKEIETLKQDYENKIKELSESSKSKESGHS 117 Query: 952 KNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEI 1011 + E +++LE ++ K ++ + EL + E +K K Q +S D +EQ I E+ Sbjct: 118 DDGEVISELEDEINRLKEELDKSKSHNTELEAILQENEEKLNSKSQ-ESTD-SEQKIKEL 175 Query: 1012 NKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQL 1071 + L+ + E+ + N +++ + +++ + ++ ++ E++ K+ Sbjct: 176 TETIQSLQNSNTEMQNSQDDLKNQIEKLKKIINQKDDDISKHLSDIQALQTEIENSDKEN 235 Query: 1072 LDSKQHNEELQILVREQDDQIKE-LKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDX 1130 + +Q ++L + E++ Q+ + LKE++ +E K+E S E + N ++ Sbjct: 236 QEIQQEKQKLIDELNEKNQQLTDQLKESQENYEKL--KSE-----SNDEKVGQ--NELNE 286 Query: 1131 XXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDV 1190 LK Q E +Q ++ N+++ E K+ + + N +LT Sbjct: 287 KLLAAESDINDLKSQIESN--------NQQISEYNSQISELQQKVDKYKVSNDQLTASQA 338 Query: 1191 VNQEQINQLKSKLEQLNTENDNLLSTVAELRSS-------ISSAVDQRGFEIAELWKQHL 1243 +++ S++E+L +EN+ + +L+SS + +D +I+EL L Sbjct: 339 ELSQKLEDSTSEIEKLKSENNEKSQAITDLQSSNNTNNENLLKQLDLLSSKISELENSSL 398 Query: 1244 AQREADFQKTEH--ELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQD 1301 A + + TE L + S + +E +L + +S Q+E +K+ + SL N Sbjct: 399 ALKSENKTLTEQIGSLDHENSKLKRDFE-VLSNEKSKLQKENDKVKADIEQLSLSN---- 453 Query: 1302 KEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQ 1361 + + L + NQI L+ E DE + + E +S Sbjct: 454 -SDEIGKLNDLIQSKDNQISELQKE-NDENMTNKAKLEEEIKRSAEEIENKEKEIESLNS 511 Query: 1362 MQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTH 1421 E ++ E KK+ +++ E + E +++ K SEI +H Sbjct: 512 QLENLKKSMEESEEGDKKTLVEMNQKISDLNSMISENEKIIEEKQSEIDQKQSEIDSLSH 571 Query: 1422 EYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESE 1481 E L Q+ DE + YE L EKES L +N + E Q E + Sbjct: 572 E-NQDLQQKLDEMKQ------NYEDEKSKLISEKES--VDHELNELKNKSEQEKSQNEEK 622 Query: 1482 IERV-KLIEELNVKITE-SVSLNKQVAELNKALEEEVAKTNE 1521 IE++ K IEE+N + E S N + + L + E+ K NE Sbjct: 623 IEKLNKEIEEINKQNEELSKQNNDEFSNLIQEKNNEINKLNE 664 Score = 118 bits (285), Expect = 1e-24 Identities = 144/662 (21%), Positives = 306/662 (46%), Gaps = 54/662 (8%) Query: 699 LENDKEDIMNKLQNYIQENMDLTDKLEKMSAEK------ISELLAKINHEEQSKIQTQFG 752 ++++ ++ +L+ QEN +L KL+++++E+ S+L A+I E + K++T+ Sbjct: 1 MDDEIAELTEQLELMDQENTELKQKLDEITSERDNLKNSNSQLSAEI-EELKKKVETE-N 58 Query: 753 IDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKA 812 D +I E IE++ +EL + K++ L + I E + E K +L + K+ Sbjct: 59 NDEEINELTEEIESLSAELEQEKTKNENLNKEI---ETLKQDYENKIKELSESSKSKESG 115 Query: 813 YS---EYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKE-LQKKNQILLEENQNLQIS 868 +S E + ++ +NRL +D + +L I EN+E L K+Q + Q ++ Sbjct: 116 HSDDGEVISELEDEINRLKEELDKSKSHNTELEAILQENEEKLNSKSQESTDSEQKIKEL 175 Query: 869 LSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDL 928 +Q N+ E N D +++ K + + + ++ + + Q L + EIE+ Sbjct: 176 TETIQSLQNSNTEMQNSQDDLKNQIEKLKKIINQKDDDISKHLSDIQAL----QTEIENS 231 Query: 929 EIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLEL 988 + E N +I+ +K+++E EKN + QL+ + Y+ N N++N +L Sbjct: 232 DKE-NQEIQQ--EKQKLIDELNEKNQQLTDQLKESQENYEKLKSESNDEKVGQNELNEKL 288 Query: 989 IDKHVQKQQTQSP-DYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYE 1047 + +S + Q I+E N + L+QK ++ N ++ +Q + D Sbjct: 289 LAAESDINDLKSQIESNNQQISEYNSQISELQQKVDKYKVSNDQLTASQAELSQKLEDST 348 Query: 1048 SKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIP 1107 S++ + K EN E+ Q ++ + +NE L + +I EL+ + L Sbjct: 349 SEIEKL--KSEN-NEKSQAITDLQSSNNTNNENLLKQLDLLSSKISELENSSLAL----- 400 Query: 1108 KTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQ---ERSVL--QEQSA 1162 K+E ++ I + D N K+Q+E + ++ E+ L ++ Sbjct: 401 KSENKTLTEQIGSL--DHENSKLKRDFEVLSNEKSKLQKENDKVKADIEQLSLSNSDEIG 458 Query: 1163 KLNTELQECYTKIIQLETLNTE-LTGHDVVNQ------EQINQLKSKLEQLNTENDNLLS 1215 KLN +Q +I +L+ N E +T + + E+I + ++E LN++ +NL Sbjct: 459 KLNDLIQSKDNQISELQKENDENMTNKAKLEEEIKRSAEEIENKEKEIESLNSQLENLKK 518 Query: 1216 TVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFES------KYE 1269 ++ E + + +I++L +++ E ++ + E+ + S +S + Sbjct: 519 SMEESEEGDKKTLVEMNQKISDL-NSMISENEKIIEEKQSEIDQKQSEIDSLSHENQDLQ 577 Query: 1270 QLLDSVQSSTQEETNKIVT-MEQVTSLQNKLQDKEEHLRNLQEKYADVIN-QIEILRSEI 1327 Q LD ++ + ++E +K+++ E V N+L++K E ++ E+ + +N +IE + + Sbjct: 578 QKLDEMKQNYEDEKSKLISEKESVDHELNELKNKSEQEKSQNEEKIEKLNKEIEEINKQN 637 Query: 1328 ED 1329 E+ Sbjct: 638 EE 639 Score = 113 bits (271), Expect = 5e-23 Identities = 159/711 (22%), Positives = 326/711 (45%), Gaps = 62/711 (8%) Query: 556 EIVRLTEELHHLSQKVAELEEEKGNLQL---HLVDYDSGRMIESDVYKKMIEMENLAETR 612 EI LTE+L + Q+ EL+++ + +L + +S E + KK +E EN E Sbjct: 4 EIAELTEQLELMDQENTELKQKLDEITSERDNLKNSNSQLSAEIEELKKKVETENNDEEI 63 Query: 613 LKAISLLESQKFDLVQELHILQQKYDEVEDKLADI-SQLQSDQVCSEIKSVHLEEQIDAL 671 + +ES +L QE + E+E D ++++ S+ K + + + Sbjct: 64 NELTEEIESLSAELEQEKTKNENLNKEIETLKQDYENKIKELSESSKSKESGHSDDGEVI 123 Query: 672 SASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEK 731 S + E+ + E +LDK + + T +LE ++ KL + QE+ D K+++++ E Sbjct: 124 SELEDEINRLKE--ELDKSKSHNT--ELEAILQENEEKLNSKSQESTDSEQKIKELT-ET 178 Query: 732 ISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDR 791 I + L N E Q+ +Q + +I++ I + ++SK+ S I L+ I + Sbjct: 179 I-QSLQNSNTEMQN---SQDDLKNQIEKLKKIINQKDDDISKHLSDIQALQTEIENSDKE 234 Query: 792 RYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLE--IEHENK 849 ++++ +L L EK + ++ + E +L + ++V + +L E + E+ Sbjct: 235 NQEIQQEKQKLIDELNEKNQQLTDQLKESQENYEKLKSESNDEKVGQNELNEKLLAAESD 294 Query: 850 ELQKKNQILLEENQNLQIS-----LSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLE 904 K+QI E+ N QIS +S++QQ + K + L S++ Q +L D Sbjct: 295 INDLKSQI---ESNNQQISEYNSQISELQQKVDKY--KVSNDQLTASQAELSQ-KLEDST 348 Query: 905 SNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQL 964 S ++++ E+ +K + I DL+ NT E+ ++ +L+ K + L+++ Sbjct: 349 SEIEKLKSENN----EKSQAITDLQSSNNTNNENLLKQLDLLSSKISELENSSLALKSEN 404 Query: 965 QEYKNNIENLNMNVEELNKMNLELIDKH---VQKQQTQSPDYTEQY----INEINKLNAL 1017 + I +L+ +L K + E++ +QK+ + EQ +EI KLN L Sbjct: 405 KTLTEQIGSLDHENSKL-KRDFEVLSNEKSKLQKENDKVKADIEQLSLSNSDEIGKLNDL 463 Query: 1018 LKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQH 1077 ++ KD +I L QK N+ M+ + E ++ + ++EN E+E++ ++ QL + K+ Sbjct: 464 IQSKDNQISEL-QKENDEN---MTNKAKLEEEIKRSAEEIENKEKEIESLNSQLENLKKS 519 Query: 1078 NEELQILVREQDDQIKELKETKLTFEMNIPKTEG-MIISSTIEPMSDDANNVDXXXXXXX 1136 EE E+ D+ ++ + ++N +E II + + +D Sbjct: 520 MEE-----SEEGDKKTLVEMNQKISDLNSMISENEKIIEEKQSEIDQKQSEIDSLSHENQ 574 Query: 1137 XXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQI 1196 L + ++ + E+S L + ++ EL E K Q ++ N+E+I Sbjct: 575 DLQQKLD-EMKQNYEDEKSKLISEKESVDHELNELKNKSEQEKS----------QNEEKI 623 Query: 1197 NQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQRE 1247 +L ++E++N +N+ L + S+ + ++ EI +L ++ +R+ Sbjct: 624 EKLNKEIEEINKQNEELSK---QNNDEFSNLIQEKNNEINKLNEETSRKRK 671 Score = 109 bits (262), Expect = 6e-22 Identities = 141/647 (21%), Positives = 293/647 (45%), Gaps = 53/647 (8%) Query: 495 DVNVKDLIEKLKSAEEQITQLN---DEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVS 551 D + +L E+L+ +++ T+L DEI + N+ S ++++++K ++ Sbjct: 2 DDEIAELTEQLELMDQENTELKQKLDEITSERDNLKNSNSQLSAEIEELKKKVET----E 57 Query: 552 DSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAET 611 ++++EI LTEE+ LS AELE+EK + + ++ + + K++ E E+ Sbjct: 58 NNDEEINELTEEIESLS---AELEQEKTKNENLNKEIETLKQDYENKIKELSESSKSKES 114 Query: 612 RL----KAISLLESQKFDLVQELHILQQKYDEVEDKLAD----ISQLQSDQVCSEIKSVH 663 + IS LE + L +EL + E+E L + ++ + SE K Sbjct: 115 GHSDDGEVISELEDEINRLKEELDKSKSHNTELEAILQENEEKLNSKSQESTDSEQKIKE 174 Query: 664 LEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDK 723 L E I +L S E+ ++LK E+L I ++D ++ +Q +Q ++ +DK Sbjct: 175 LTETIQSLQNSNTEMQNSQDDLKNQIEKLKKIINQKDDDISKHLSDIQ-ALQTEIENSDK 233 Query: 724 LEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEE 783 + ++ +L+ ++N + Q + +++E E ++SE + K L E Sbjct: 234 ENQEIQQEKQKLIDELNEKNQQ-------LTDQLKESQENYEKLKSESNDEKVGQNELNE 286 Query: 784 SIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRL-AVLMDHDRVVEKQLL 842 + + E + L S ++ + SEY Q EL ++ + +D++ Q Sbjct: 287 KL-------LAAESDINDLKSQIESNNQQISEYNSQISELQQKVDKYKVSNDQLTASQ-A 338 Query: 843 EIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEK-ANRTDLAESESTKYQTQLR 901 E+ + ++ + + L EN +++D+Q N E + DL S+ ++ + Sbjct: 339 ELSQKLEDSTSEIEKLKSENNEKSQAITDLQSSNNTNNENLLKQLDLLSSKISELENSSL 398 Query: 902 DLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKV---LNEKYEKNIEYVT 958 L+S K +T + +L + K D E+ N + + + KV + + N + + Sbjct: 399 ALKSENKTLTEQIGSLDHENSKLKRDFEVLSNEKSKLQKENDKVKADIEQLSLSNSDEIG 458 Query: 959 QLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALL 1018 +L +Q N I L +E N N +++ + K+ + + E+ I +N L Sbjct: 459 KLNDLIQSKDNQISELQKENDE-NMTNKAKLEEEI-KRSAEEIENKEKEIESLNSQLENL 516 Query: 1019 KQKDEE--------IIALNQKIN--NAQVS-YMSMVSDYESKLAQFTTKLENMEEEMQRV 1067 K+ EE ++ +NQKI+ N+ +S ++ + +S++ Q ++++++ E Q + Sbjct: 517 KKSMEESEEGDKKTLVEMNQKISDLNSMISENEKIIEEKQSEIDQKQSEIDSLSHENQDL 576 Query: 1068 SKQLLDSKQ-HNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMI 1113 ++L + KQ + +E L+ E++ EL E K E + E I Sbjct: 577 QQKLDEMKQNYEDEKSKLISEKESVDHELNELKNKSEQEKSQNEEKI 623 Score = 109 bits (261), Expect = 8e-22 Identities = 144/697 (20%), Positives = 291/697 (41%), Gaps = 59/697 (8%) Query: 879 LVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIES 938 + E + +L + E+T+ + +L ++ S + + + L EIE+L+ ++E+ Sbjct: 5 IAELTEQLELMDQENTELKQKLDEITSERDNLKNSNSQL----SAEIEELK----KKVET 56 Query: 939 AIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEEL-----NKMNLELIDKHV 993 D+++ NE E+ + L A+L++ K ENLN +E L NK+ EL + Sbjct: 57 ENNDEEI-NELTEE----IESLSAELEQEKTKNENLNKEIETLKQDYENKIK-ELSESSK 110 Query: 994 QKQQTQSPD--YTEQYINEINKLNALL---KQKDEEIIALNQKINNAQVSYMSMVSDYES 1048 K+ S D + +EIN+L L K + E+ A+ Q+ S +D E Sbjct: 111 SKESGHSDDGEVISELEDEINRLKEELDKSKSHNTELEAILQENEEKLNSKSQESTDSEQ 170 Query: 1049 KLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQI-KELKETK-LTFEMNI 1106 K+ + T +++++ + D K E+L+ ++ ++DD I K L + + L E+ Sbjct: 171 KIKELTETIQSLQNSNTEMQNSQDDLKNQIEKLKKIINQKDDDISKHLSDIQALQTEIEN 230 Query: 1107 PKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNT 1166 E I + + D+ N + + + E E+ E + KL Sbjct: 231 SDKENQEIQQEKQKLIDELNEKNQQLTDQLKESQENYEKLKSESNDEKVGQNELNEKLLA 290 Query: 1167 ELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISS 1226 + Q+E+ N +++ ++ QI++L+ K+++ ND L ++ AEL + Sbjct: 291 AESDINDLKSQIESNNQQISEYN----SQISELQQKVDKYKVSNDQLTASQAELSQKLED 346 Query: 1227 AVDQRGFEIAELWKQHLAQREADFQKTEH----ELRVQLSAFESKYEQLLDSVQSSTQEE 1282 + + E + +Q D Q + + L QL SK +L +S S + Sbjct: 347 STSE--IEKLKSENNEKSQAITDLQSSNNTNNENLLKQLDLLSSKISELENS--SLALKS 402 Query: 1283 TNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXX 1342 NK +T EQ+ SL ++ + L + + + + + ++++IE ++ Sbjct: 403 ENKTLT-EQIGSLDHENSKLKRDFEVLSNEKSKLQKENDKVKADIEQLSLS--------- 452 Query: 1343 XXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKV 1402 D + Q ++ I + +EN + + + + E ++ Sbjct: 453 ------NSDEIGKLNDLIQSKDNQISELQKENDENMTNKAKLEEEIKRSAEEIENKEKEI 506 Query: 1403 LELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYE---KESEL 1459 L QLE + + TL + N + ++ + E EK IE+ E K+SE+ Sbjct: 507 ESLNSQLENLKKSMEESEEGDKKTLVEMNQKISDLNSMISENEKIIEEKQSEIDQKQSEI 566 Query: 1460 AILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKT 1519 L + + + M++ E E+ KLI E E L + + EE++ K Sbjct: 567 DSLSHENQDLQQKLDEMKQNYEDEKSKLISEKESVDHELNELKNKSEQEKSQNEEKIEKL 626 Query: 1520 NEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQK 1556 N+ + Q E+ N++ N+++ +++I K Sbjct: 627 NKEIEEINKQNEELSKQNND--EFSNLIQEKNNEINK 661 Score = 107 bits (257), Expect = 2e-21 Identities = 151/714 (21%), Positives = 311/714 (43%), Gaps = 62/714 (8%) Query: 321 MTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTAS 380 + ELT+++EL++ N +++Q E+ ++ + + +S+ ++ + ++ + Sbjct: 5 IAELTEQLELMDQENTELKQKLDEITSERDNLKNSNSQLSAEIEELKKKVETENNDEEIN 64 Query: 381 KMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXX 440 ++ LS+E L Q+ K N N+ I++L +D +K I E Sbjct: 65 ELTEEIESLSAE-LEQEKTKNENLNK------EIETLKQDYENK---IKELSESSKSKES 114 Query: 441 XXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVN--V 498 +I++L+ E + E L ++ ++ I + E+ + E D + Sbjct: 115 GHSDDGEVISELEDEINRLKE--ELDKSKSHNTELEAILQENEEKLNSKSQESTDSEQKI 172 Query: 499 KDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIV 558 K+L E ++S + T++ + D + K+K K + K + + + + Sbjct: 173 KELTETIQSLQNSNTEMQNSQDDLKNQIEKLKKIINQKDDDISKHLSDIQALQTEIENSD 232 Query: 559 RLTEELHHLSQK-VAELEEEKGNLQLHLVD-YDSGRMIESDVYKKMIEMENLAETRLKAI 616 + +E+ QK + EL E+ L L + ++ ++S+ + + L E L A Sbjct: 233 KENQEIQQEKQKLIDELNEKNQQLTDQLKESQENYEKLKSESNDEKVGQNELNEKLLAA- 291 Query: 617 SLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKK 676 ES DL ++ Q+ E +++++ Q S D L+AS+ Sbjct: 292 ---ESDINDLKSQIESNNQQISEYNSQISELQQKVDKYKVSN----------DQLTASQA 338 Query: 677 ELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELL 736 EL+ +E+ + E+L K N+K + LQ+ N + K + + KISEL Sbjct: 339 ELSQKLEDSTSEIEKL----KSENNEKSQAITDLQSSNNTNNENLLKQLDLLSSKISELE 394 Query: 737 -AKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESI-AVMEDRRYS 794 + + + ++K T+ I + E + E LS KS++ + + + A +E S Sbjct: 395 NSSLALKSENKTLTE-QIGSLDHENSKLKRDFEV-LSNEKSKLQKENDKVKADIEQLSLS 452 Query: 795 LERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKK 854 + +L +Q K SE + DE + A L + +++ EIE++ KE++ Sbjct: 453 NSDEIGKLNDLIQSKDNQISELQKENDENMTNKAKLEEE---IKRSAEEIENKEKEIESL 509 Query: 855 NQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKY----QTQLRDLESNLKRI 910 N L ++++ S ++ + +K + + SE+ K Q+++ +S + + Sbjct: 510 NSQLENLKKSMEESEEGDKKTLVEMNQKISDLNSMISENEKIIEEKQSEIDQKQSEIDSL 569 Query: 911 THEHQTL---IVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEY 967 +HE+Q L + + K+ ED + + ++ ES + LNE K+ + +Q E ++++ Sbjct: 570 SHENQDLQQKLDEMKQNYEDEKSKLISEKESVDHE---LNELKNKSEQEKSQNEEKIEKL 626 Query: 968 KNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQK 1021 IE +N EEL+K N + +Q++ NEINKLN +K Sbjct: 627 NKEIEEINKQNEELSKQNNDEFSNLIQEKN-----------NEINKLNEETSRK 669 Score = 96.3 bits (229), Expect = 6e-18 Identities = 131/672 (19%), Positives = 287/672 (42%), Gaps = 60/672 (8%) Query: 946 LNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTE 1005 L E+ E + T+L+ +L E + +NL + +L+ +E + K V+ + + Sbjct: 8 LTEQLELMDQENTELKQKLDEITSERDNLKNSNSQLSA-EIEELKKKVETENND--EEIN 64 Query: 1006 QYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDY-------ESKLAQFTTKLE 1058 + EI L+A L+Q+ + LN++I + Y + + + ES + + Sbjct: 65 ELTEEIESLSAELEQEKTKNENLNKEIETLKQDYENKIKELSESSKSKESGHSDDGEVIS 124 Query: 1059 NMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTI 1118 +E+E+ R+ ++L SK HN EL+ +++E ++++ + E I + I S + Sbjct: 125 ELEDEINRLKEELDKSKSHNTELEAILQENEEKLNSKSQESTDSEQKIKELTETIQS--L 182 Query: 1119 EPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQ------EQSAKLNTELQECY 1172 + + + N + Q++++ + S +Q E S K N E+Q+ Sbjct: 183 QNSNTEMQNSQDDLKNQIEKLKKIINQKDDDISKHLSDIQALQTEIENSDKENQEIQQEK 242 Query: 1173 TKII-QLETLNTELTGHDVVNQEQINQLKSKLEQ----LNTENDNLLSTVAELRSSISSA 1227 K+I +L N +LT +QE +LKS+ N N+ LL+ +++ + + S Sbjct: 243 QKLIDELNEKNQQLTDQLKESQENYEKLKSESNDEKVGQNELNEKLLAAESDI-NDLKSQ 301 Query: 1228 VDQRGFEIAELWKQ--HLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNK 1285 ++ +I+E Q L Q+ ++ + +L + K E ++ E K Sbjct: 302 IESNNQQISEYNSQISELQQKVDKYKVSNDQLTASQAELSQKLEDSTSEIEKLKSENNEK 361 Query: 1286 IVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXX 1345 + +T LQ+ E+L + Q+++L S+I + + + Sbjct: 362 ---SQAITDLQSSNNTNNENL----------LKQLDLLSSKISELENS-SLALKSENKTL 407 Query: 1346 XXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLEL 1405 L EN K+ E ++ E ++L+K + +D K+ +L Sbjct: 408 TEQIGSLDHENSKLKRDFEV----LSNEKSKLQKENDKVKADIEQLSLSNSDEIGKLNDL 463 Query: 1406 THQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKES-ELAILRL 1464 + + SE+ ++ E + +E + +++ EK IE L + E+ + ++ Sbjct: 464 IQSKDNQISELQKENDENMTNKAKLEEEIKRSAEEIENKEKEIESLNSQLENLKKSMEES 523 Query: 1465 KMHENANHYETMQKESEI-----ERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKT 1519 + + E QK S++ E K+IEE +I + S ++ N+ L++ K Sbjct: 524 EEGDKKTLVEMNQKISDLNSMISENEKIIEEKQSEIDQKQSEIDSLSHENQDLQQ---KL 580 Query: 1520 NEMQTALENQEIEIVT----LNDEITNLQNMVRASSSKIQKHVSFAS---DTKQGRDEQL 1572 +EM+ E+++ ++++ ++ E+ L+N S+ ++ + + + ++E+L Sbjct: 581 DEMKQNYEDEKSKLISEKESVDHELNELKNKSEQEKSQNEEKIEKLNKEIEEINKQNEEL 640 Query: 1573 DNTMNKELLDAV 1584 N E + + Sbjct: 641 SKQNNDEFSNLI 652 Score = 94.3 bits (224), Expect = 2e-17 Identities = 141/701 (20%), Positives = 293/701 (41%), Gaps = 53/701 (7%) Query: 778 ICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVV 837 I L E + +M+ L++K D++ S + + S+ + + +EL ++ ++D + Sbjct: 5 IAELTEQLELMDQENTELKQKLDEITSERDNLKNSNSQLSAEIEELKKKVET-ENNDEEI 63 Query: 838 EKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQ 897 + EIE + EL+++ +N+NL + ++Q Y ++ +L+ES +K Sbjct: 64 NELTEEIESLSAELEQEKT----KNENLNKEIETLKQDYENKIK-----ELSESSKSKES 114 Query: 898 TQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYV 957 D E + E + I + K+E+ D NT++E+ +++ + EK + Sbjct: 115 GHSDDGE-----VISELEDEINRLKEEL-DKSKSHNTELEAILQENE---EKLNSKSQES 165 Query: 958 TQLEAQLQEYKNNIENL-NMNVEELNKMN-LELIDKHVQKQQTQSPDYTEQYINEINKLN 1015 T E +++E I++L N N E N + L+ + ++K Q D +++++I L Sbjct: 166 TDSEQKIKELTETIQSLQNSNTEMQNSQDDLKNQIEKLKKIINQKDDDISKHLSDIQALQ 225 Query: 1016 ALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSK 1075 ++ D+E NQ+I Q ++ + K Q T +L+ +E +++ + D K Sbjct: 226 TEIENSDKE----NQEI---QQEKQKLIDELNEKNQQLTDQLKESQENYEKLKSESNDEK 278 Query: 1076 QHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMI--ISSTIEP--MSDD---ANNV 1128 EL + + I +LK + I + I + ++ +S+D A+ Sbjct: 279 VGQNELNEKLLAAESDINDLKSQIESNNQQISEYNSQISELQQKVDKYKVSNDQLTASQA 338 Query: 1129 DXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTE-----LQECYTKIIQLETLNT 1183 + K++ E + + S N E L +KI +LE + Sbjct: 339 ELSQKLEDSTSEIEKLKSENNEKSQAITDLQSSNNTNNENLLKQLDLLSSKISELENSSL 398 Query: 1184 ELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSS---ISSAVDQRGFEIA-ELW 1239 L + EQI L + +L + + L + ++L+ + + ++Q + E+ Sbjct: 399 ALKSENKTLTEQIGSLDHENSKLKRDFEVLSNEKSKLQKENDKVKADIEQLSLSNSDEIG 458 Query: 1240 KQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTS-LQNK 1298 K + + D Q +E L+ + + +L + ++ S +E NK +E + S L+N Sbjct: 459 KLNDLIQSKDNQISE--LQKENDENMTNKAKLEEEIKRSAEEIENKEKEIESLNSQLENL 516 Query: 1299 LQDKEEHLRNLQEKYADVINQIEILRSEI-EDEKVAFXXXXXXXXXXXXXXXXDLRTENQ 1357 + EE ++ ++ +I L S I E+EK+ L ENQ Sbjct: 517 KKSMEESEEGDKKTLVEMNQKISDLNSMISENEKII--EEKQSEIDQKQSEIDSLSHENQ 574 Query: 1358 SYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIY 1417 +Q ++ N +E ++L + +++ E +L + EI Sbjct: 575 DLQQKLDEMKQNYEDEKSKLISEKESVDHELNELKNKSEQEKSQNEEKIEKLNKEIEEIN 634 Query: 1418 QKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESE 1458 ++ E + Q NDEF N+ Q+ ++ + T K + Sbjct: 635 KQNEELS---KQNNDEFSNLIQEKNNEINKLNEETSRKRKK 672 Score = 69.3 bits (162), Expect = 8e-10 Identities = 87/398 (21%), Positives = 180/398 (45%), Gaps = 31/398 (7%) Query: 1194 EQINQLKSKLEQLNTENDNLLSTVAEL---RSSISSAVDQRGFEIAELWKQHLAQREADF 1250 ++I +L +LE ++ EN L + E+ R ++ ++ Q EI EL K+ + E + Sbjct: 3 DEIAELTEQLELMDQENTELKQKLDEITSERDNLKNSNSQLSAEIEELKKK--VETENND 60 Query: 1251 QKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNK-IVTMEQVTSLQNKLQDKEEHLRNL 1309 ++ +EL ++ + ++ EQ + + E NK I T++Q +NK+++ E ++ Sbjct: 61 EEI-NELTEEIESLSAELEQ-----EKTKNENLNKEIETLKQ--DYENKIKELSESSKSK 112 Query: 1310 QEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILN 1369 + ++D E++ SE+EDE L+ EN+ + Q + Sbjct: 113 ESGHSD---DGEVI-SELEDEINRLKEELDKSKSHNTELEAILQ-ENEEKLNSKSQESTD 167 Query: 1370 INEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQ 1429 ++ +L ++ +D + ++ +L + KD +I + + T+ Sbjct: 168 SEQKIKELTETIQSLQNSNTEMQNSQDDLKNQIEKLKKIINQKDDDISKHLSDIQALQTE 227 Query: 1430 -RNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLI 1488 N + EN Q++ + ++++ D EK +L ++ E+ +YE ++ ES E+V Sbjct: 228 IENSDKEN--QEIQQEKQKLIDELNEKNQQLTD---QLKESQENYEKLKSESNDEKVGQ- 281 Query: 1489 EELNVKITESVS----LNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQ 1544 ELN K+ + S L Q+ N+ + E ++ +E+Q ++ ++ L L Sbjct: 282 NELNEKLLAAESDINDLKSQIESNNQQISEYNSQISELQQKVDKYKVSNDQLTASQAELS 341 Query: 1545 NMVRASSSKIQKHVSFASDTKQG-RDEQLDNTMNKELL 1581 + S+S+I+K S ++ Q D Q N N E L Sbjct: 342 QKLEDSTSEIEKLKSENNEKSQAITDLQSSNNTNNENL 379 Score = 67.7 bits (158), Expect = 2e-09 Identities = 109/536 (20%), Positives = 231/536 (43%), Gaps = 63/536 (11%) Query: 144 VTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXX 203 + L+ TI+ N+ + +Q ++ I L++ IN+KD I Sbjct: 172 IKELTETIQSLQNSNTEMQNSQDDLKNQIEKLKKIINQKDDDI----------------- 214 Query: 204 XXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRIS-SLEEANKLLEA 262 D + T++ EN E + EKQ+L+ ++ K+ +++ L+E+ + E Sbjct: 215 ----SKHLSDIQALQTEI-ENSDKENQEIQQEKQKLIDELNEKNQQLTDQLKESQENYEK 269 Query: 263 ARFEISLEHSKLAQ-ELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANM 321 + E + E K+ Q EL + K IE + ++ +E + + Sbjct: 270 LKSESNDE--KVGQNELNEKLLAAESDIND----LKSQIESNNQQISEYN-------SQI 316 Query: 322 TELTKKIELLEHLNCQIRQTNKELENKLATMGTE-SKAVSSPSKKGSPLISRKSGRNTAS 380 +EL +K++ + N Q+ + EL KL +E K S ++K + +S NT + Sbjct: 317 SELQQKVDKYKVSNDQLTASQAELSQKLEDSTSEIEKLKSENNEKSQAITDLQSSNNTNN 376 Query: 381 K--------MKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKD 432 + + S S+L + +L ++ K +I L+ L +D E + +EK Sbjct: 377 ENLLKQLDLLSSKISELENSSLALKSENKTLTEQIGSLDHENSKLKRDF---EVLSNEKS 433 Query: 433 TXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDE 492 I QL L + + ++ ++D N+I+++Q++ + + ++ Sbjct: 434 KLQKENDKVKAD----IEQLSLSNSDEI---GKLNDLIQSKD-NQISELQKENDENMTNK 485 Query: 493 IK-DVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQM-QKTIDNFSKV 550 K + +K E++++ E++I LN +++ K+M + + K L +M QK D S + Sbjct: 486 AKLEEEIKRSAEEIENKEKEIESLNSQLENLKKSMEESEEGDKKTLVEMNQKISDLNSMI 545 Query: 551 SDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAE 610 S++ K I E+ ++ L E +LQ L D + D K+I + + Sbjct: 546 SENEKIIEEKQSEIDQKQSEIDSLSHENQDLQQKL---DEMKQNYEDEKSKLISEKESVD 602 Query: 611 TRLKAI-SLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLE 665 L + + E +K +++ L ++ +E+ + ++S+ +D+ + I+ + E Sbjct: 603 HELNELKNKSEQEKSQNEEKIEKLNKEIEEINKQNEELSKQNNDEFSNLIQEKNNE 658 Score = 41.9 bits (94), Expect = 0.14 Identities = 66/312 (21%), Positives = 135/312 (43%), Gaps = 27/312 (8%) Query: 143 DVTHLSNTIKEKDNALSVLQVKMKIMETTILD----LQEKINEKDQ---IIEAKNKATTX 195 ++ L + EK A++ LQ +L L KI+E + ++++NK T Sbjct: 350 EIEKLKSENNEKSQAITDLQSSNNTNNENLLKQLDLLSSKISELENSSLALKSENKTLTE 409 Query: 196 XXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWK-------DEKQRLLKDIESKDV 248 E + +K+Q+ ++A+ + DE +L I+SKD Sbjct: 410 QIGSLDHENSKLKRDFEVLSNEKSKLQKENDKVKADIEQLSLSNSDEIGKLNDLIQSKDN 469 Query: 249 RISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCE--E 306 +IS L++ N + ++ E + A+E+E L K+S+E S E + Sbjct: 470 QISELQKENDENMTNKAKLEEEIKRSAEEIENKEKEIESLNSQLENL-KKSMEESEEGDK 528 Query: 307 KTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKEL-----ENKLATMGTESKAVSS 361 KT +E + N + +++ +++E +I Q E+ EN+ + + Sbjct: 529 KTLVEMNQKISDLN-SMISENEKIIEEKQSEIDQKQSEIDSLSHENQDLQQKLDEMKQNY 587 Query: 362 PSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDL 421 +K + ++S + +++K+ Q S+ N++ +K+NK EI ++ + L+K Sbjct: 588 EDEKSKLISEKESVDHELNELKNKSEQEKSQ--NEEKIEKLNK-EIEEINKQNEELSKQN 644 Query: 422 VDK-EYVISEKD 432 D+ +I EK+ Sbjct: 645 NDEFSNLIQEKN 656 Score = 40.3 bits (90), Expect = 0.43 Identities = 45/225 (20%), Positives = 92/225 (40%), Gaps = 14/225 (6%) Query: 143 DVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXX 202 ++ L++ I+ KDN +S LQ + T L+E+I + IE K K Sbjct: 456 EIGKLNDLIQSKDNQISELQKENDENMTNKAKLEEEIKRSAEEIENKEKEIESLNSQLEN 515 Query: 203 XXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEA 262 E K+ + +M + + + + + K IE K S +++ +++ Sbjct: 516 LKKSMEESEEGDKKTLVEMNQKISDLNSMISENE----KIIEEKQ---SEIDQKQSEIDS 568 Query: 263 ARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEE-KTEIEEKGSLEIANM 321 +S E+ L Q+L++ K+S++ E K + E++ S + Sbjct: 569 ----LSHENQDLQQKLDEMKQNYEDEKSKLIS-EKESVDHELNELKNKSEQEKSQNEEKI 623 Query: 322 TELTKKIELLEHLNCQI-RQTNKELENKLATMGTESKAVSSPSKK 365 +L K+IE + N ++ +Q N E N + E ++ + + Sbjct: 624 EKLNKEIEEINKQNEELSKQNNDEFSNLIQEKNNEINKLNEETSR 668 >UniRef50_A0DV70 Cluster: Chromosome undetermined scaffold_65, whole genome shotgun sequence; n=1; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_65, whole genome shotgun sequence - Paramecium tetraurelia Length = 1653 Score = 123 bits (296), Expect = 5e-26 Identities = 281/1462 (19%), Positives = 589/1462 (40%), Gaps = 149/1462 (10%) Query: 143 DVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXX 202 ++T L + + V + E TI L++KI E D I+ +A Sbjct: 212 EITRLMQELARHQSEAQVRTSDKEFYERTIQTLKDKIKEMDNDIQILIEAHNQNQFKLES 271 Query: 203 XXXXXXXXXEDTKQQMTKMQENFIAMEA-EWKDEKQRLLKDIESKDVRISSLE----EAN 257 + Q+ + + NF + +W+++ Q E + RI +E E Sbjct: 272 AMAESKGNMQYEIDQL-RQEVNFYQTQCKQWQEKCQVFELQKEESERRIIQMEIRVNETK 330 Query: 258 KLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLE 317 K +E + E S ++ K S K ++ L Sbjct: 331 KQIELQQNERIQRDSWQVHTIQNELENWKQKYIQLEIKTKDSETHRLRIKQLEDQNNHLR 390 Query: 318 IANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRN 377 I N + +++++L I++ N + + +SK+ + + + N Sbjct: 391 IEN-ERVKEELDILVTEFKSIQEQNNGYRLSITQLEKQSKSTVELDRYKTQVNQLNQQIN 449 Query: 378 TASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXX 437 K QL + + Q +K+I + + ++ K++ + + Sbjct: 450 N---YKVEIKQLQEQMIVQQQEKRIEIQSYTQYQYEAENHQKEIEKLRREFRQIEQLYNE 506 Query: 438 XXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELND-EIKDV 496 QL+HQ+ + LI V T E I EQ K + E++ + Sbjct: 507 MEVQVKLWKEKFYHEQLQHQEARQ--LLIDVKTQYESHTYILTQTEQDKHRIQQLELQLI 564 Query: 497 NVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNF-SKVSDSNK 555 +++ + L+ EE + +N IK + K++Q++ I+ SK D K Sbjct: 565 ELQEEVRVLQIREETYKEQISTYSVTIEN-IKQNQDQSRKVRQLELDIETLKSKCRDLEK 623 Query: 556 EIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKA 615 +++ E + L +E E +K + D + ++ K++IE + E +LK Sbjct: 624 QLLDKRNEFNLLK---SEWELDKQKITELKASNDVLLKRKPEIVKQIIETPSKQE-KLKI 679 Query: 616 ISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSV-HLEEQIDALSAS 674 L + +Q + K + + + + + Q++S + +IK + +LEE++ Sbjct: 680 QELEQQVSLLKLQSQQVSASKQEVIRETIRETVQVRSQE---DIKLIANLEEELQLWKTK 736 Query: 675 KKEL-----ALVIENLK--LDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLT------ 721 EL +V+E ++ E I++LE+ + K Q I+E + T Sbjct: 737 YYELDRRKNQVVVETIREVQQSESDKLRIQELEHQVKQSSAKKQEIIREFITQTVEVPVE 796 Query: 722 -DKLEKMSAE-KISELLAKI---NHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKS 776 DK+ E +++ L +I N +Q I Q ++ Q I+ +ESE+ K K+ Sbjct: 797 ADKIRIQQLEIQVNNLRQEIYLLNQRKQEVITQQITVEVPSQADRQIIQQLESEIVKLKT 856 Query: 777 RICRLEES----IAVMEDRRYSLERKAD-----QLGSYLQEKQKAYSEYTIQEDELVNRL 827 ++ + +S I + R + ++D QL + LQ QK Y +++ E++ Sbjct: 857 QLEFVSKSKQEVIREIITERVEVPSESDKLKIQQLQTQLQRLQKDYQYLELKKQEIIKET 916 Query: 828 AVL-----MDHDRV--VEKQLLEIEHENKEL-QKKNQILLE---------------ENQN 864 + D R+ +E QLL+I+ E + + QKK +I+ E + Q Sbjct: 917 ITVEVPSQADKSRIQLLESQLLQIKKELQIVSQKKQEIITEYITERVEVPLESDRIKIQQ 976 Query: 865 LQISLSDMQQHYNALVEKANR----TDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQ 920 L+ L +QQ Y L +K T E Q +++ LES + ++ ++ ++I Q Sbjct: 977 LESQLQKIQQEYYLLNQKKQEIIKETITVEVPQQSDQLRIQQLESLVVQLK-QNISIIQQ 1035 Query: 921 KKKEI------EDLEI----------EFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQL 964 +K+E+ E +E+ + +++ +D LN+K ++ I+ +E Sbjct: 1036 QKQEVIRETITETVEVPSQKDKLRIQQLEQELQRLTQDYYQLNQKKQQIIKETVTVEVSS 1095 Query: 965 QEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEE 1024 Q K I+ L V++L EL+ QKQ+ TE+ + ++Q ++ Sbjct: 1096 QADKFRIQQLESQVQQLKS---ELLIIQQQKQEVIREIITERVEVPVESDKIRIRQLQDQ 1152 Query: 1025 IIALNQKINNAQVSYMSMVSD---YESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEEL 1081 L + N + ++ + E +++ +E+ +Q++ + L+ Q+N E Sbjct: 1153 FSQLQRDYNQLNLKKQEVIRETVTVEVSSQADKYRIQQLEQSLQQMKMEYLNL-QNNYE- 1210 Query: 1082 QILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXX 1141 I+ +++ + IKE+ ++ K + S + ++ + + Sbjct: 1211 -IVSKKKQEVIKEVITERVEVSSPADKQRIAQLESQLSNLTMELQIISKKKQETIREVIT 1269 Query: 1142 LKVQEEEEFIQERSVLQEQSA-KLNTE---LQECYTKIIQLETLNTELTGHDVVNQEQIN 1197 +V+ +E + R + EQ KL + L + ++I+ ET E+ ++ +I Sbjct: 1270 ERVEVPKESDKRRIIELEQDLNKLQQDYIALNKTKQEVIK-ETYTIEVPSQ--ADKFKIQ 1326 Query: 1198 QLKSKLEQLNTENDNLLSTVAEL-RSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHE 1256 QL+ +L Q+ +E L S AE+ R + V+ I +L +Q ++ + D+ Sbjct: 1327 QLEMQLSQIRSEYQVLQSRKAEIVREVVEVPVESDRIRIRQL-EQQISSLQQDY------ 1379 Query: 1257 LRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADV 1316 S + K E + ++V E ++ ++ L+ +L ++L +Q++ +V Sbjct: 1380 ----FSLNQKKQEVIKETVTIEVPSEADQY----RIRQLEQQLSTLRDNLTVIQKQKQEV 1431 Query: 1317 INQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQ------EQSILNI 1370 +I++ ++ K +++ + K+ Q EQ I N+ Sbjct: 1432 ----QIIKETVQVSKQEDLFKIQNLERQLLQLQNEVQIYEKQLKEYQNSSFELEQEIKNL 1487 Query: 1371 NEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQR 1430 + +KS+ ++ + + K ++ Q E ++ E ++ L +R Sbjct: 1488 RIQLRTTQKSNQEYQEQLTSIQIKIEEGQ-KSKQIQFQYERREQEFIEQIK----LLERR 1542 Query: 1431 NDEFENVRQQLVEYEKRIEDLTYEK-ESELAILRLKMHENANHYETMQKESEIERVKLIE 1489 N+EF R++ EYE+++ E+ ++E I RLK+ +T +K+ E ER+ I+ Sbjct: 1543 NEEFRQERERYSEYERKLNYYKEEQLQNEKLIERLKL-----EIQTQKKQYE-ERIS-IQ 1595 Query: 1490 ELNVKITESVSLNKQVAELNKA 1511 E K ++ +Q + +N++ Sbjct: 1596 ESQFKKEITIIQTQQQSNVNQS 1617 Score = 110 bits (265), Expect = 3e-22 Identities = 212/1080 (19%), Positives = 488/1080 (45%), Gaps = 115/1080 (10%) Query: 529 VKSNHKLK--LKQMQKTIDNFSKVSDSN---KEIVRLTE-ELHHLSQKVAELEEEKGNLQ 582 ++ N KLK ++Q+ K ++S N K+ + + EL Q++A+L + L Sbjct: 66 LQDNRKLKEVIEQLDKDNQQLKQMSGENYNLKQKYMINQAELEAAQQELAKLRSQL--LM 123 Query: 583 LHLVDYDSGRMI---ESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDE 639 + D +S ++ + D+ M + + ++ + ++ L +++ V+E ++ KY++ Sbjct: 124 RNSSDAESSSLVARYKQDI-SSMTQQQIKSQQEITQLNALLTEQRKQVEEYLRIKSKYEQ 182 Query: 640 VEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASK-----KELALVIENLKL---DKEQ 691 DI ++ E++ ++EQ ++ + S+ +ELA ++ DKE Sbjct: 183 ------DIQTYKNRASTLELEIRSVKEQRNSTTQSEITRLMQELARHQSEAQVRTSDKEF 236 Query: 692 LYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKIN--HEEQSKIQT 749 TI+ L++ +++ N +Q I+ + KLE AE + +I+ +E + QT Sbjct: 237 YERTIQTLKDKIKEMDNDIQILIEAHNQNQFKLESAMAESKGNMQYEIDQLRQEVNFYQT 296 Query: 750 QF-GIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLER-KADQLGSYLQ 807 Q K Q +L E E + + + R+ ++ I + ++ R + + + + L+ Sbjct: 297 QCKQWQEKCQVFELQKEESERRIIQMEIRVNETKKQIELQQNERIQRDSWQVHTIQNELE 356 Query: 808 EKQKAYSEYTIQ-EDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQ 866 ++ Y + I+ +D +RL + + +E Q + EN+ ++++ IL+ E +++Q Sbjct: 357 NWKQKYIQLEIKTKDSETHRLRI-----KQLEDQNNHLRIENERVKEELDILVTEFKSIQ 411 Query: 867 ISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHE-----HQTLIVQK 921 + Y + + + + E +Y+TQ+ L + E Q ++ Q+ Sbjct: 412 ----EQNNGYRLSITQLEKQSKSTVELDRYKTQVNQLNQQINNYKVEIKQLQEQMIVQQQ 467 Query: 922 KKEIE-DLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEE 980 +K IE ++ + E+ ++ + L ++ + + ++E Q++ +K + + +E Sbjct: 468 EKRIEIQSYTQYQYEAENHQKEIEKLRREFRQIEQLYNEMEVQVKLWKEKFYHEQLQHQE 527 Query: 981 LNKMNLELIDKHVQ-KQQTQSPDYTEQYINEINKLNALLKQKDEE--IIALNQKINNAQV 1037 ++ LID Q + T TEQ + I +L L + EE ++ + ++ Q+ Sbjct: 528 ARQL---LIDVKTQYESHTYILTQTEQDKHRIQQLELQLIELQEEVRVLQIREETYKEQI 584 Query: 1038 SYMSMV-------SDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDD 1090 S S+ D K+ Q +E ++ + + + KQLLD + E +L E + Sbjct: 585 STYSVTIENIKQNQDQSRKVRQLELDIETLKSKCRDLEKQLLDKR---NEFNLLKSEWEL 641 Query: 1091 QIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEF 1150 +++ E K + ++ + K + I+ IE S LK+QE E Sbjct: 642 DKQKITELKASNDV-LLKRKPEIVKQIIETPSKQEK---------------LKIQELE-- 683 Query: 1151 IQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHD---VVNQEQINQL-KSKLEQL 1206 Q+ S+L+ QS +++ QE + I+ ET+ + D + N E+ QL K+K +L Sbjct: 684 -QQVSLLKLQSQQVSASKQEVIRETIR-ETVQVR-SQEDIKLIANLEEELQLWKTKYYEL 740 Query: 1207 N-TENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQK-TEHELRVQLSAF 1264 + +N ++ T+ E++ S S + R E+ KQ A+++ ++ + V + A Sbjct: 741 DRRKNQVVVETIREVQQSESDKL--RIQELEHQVKQSSAKKQEIIREFITQTVEVPVEAD 798 Query: 1265 ESKYEQLLDSVQSSTQE-----ETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQ 1319 + + +QL V + QE + + V +Q+T ++ Q + ++ L+ + + Q Sbjct: 799 KIRIQQLEIQVNNLRQEIYLLNQRKQEVITQQIT-VEVPSQADRQIIQQLESEIVKLKTQ 857 Query: 1320 IEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKK 1379 +E + S+ + E + + + Q + ++ L + ++ ++ K Sbjct: 858 LEFV-SKSKQEVIREIITERVEVPSESDKLKIQQLQTQLQRLQKDYQYLELKKQ--EIIK 914 Query: 1380 SSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRND-EFENVR 1438 + R+ E+++L++ +L++ + + EY +T+R + E+ R Sbjct: 915 ETITVEVPSQADKSRIQLLESQLLQIKKELQIVSQKKQEIITEY---ITERVEVPLESDR 971 Query: 1439 QQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQ--KESEIERVKLIEELNVKIT 1496 ++ + E +++ + + E +L K E T++ ++S+ R++ +E L V++ Sbjct: 972 IKIQQLESQLQKI----QQEYYLLNQKKQEIIKETITVEVPQQSDQLRIQQLESLVVQLK 1027 Query: 1497 ESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNL-QNMVRASSSKIQ 1555 +++S+ +Q + + + E + +T E+ + + ++ I L E+ L Q+ + + K Q Sbjct: 1028 QNISIIQQ--QKQEVIRETITETVEVPS--QKDKLRIQQLEQELQRLTQDYYQLNQKKQQ 1083 Score = 70.9 bits (166), Expect = 3e-10 Identities = 140/692 (20%), Positives = 282/692 (40%), Gaps = 65/692 (9%) Query: 895 KYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEI--EFNTQIESAIRDKKVLN---EK 949 KYQT + S KR+ +Q+ +K ED +I + + E ++D + L E+ Sbjct: 21 KYQTTSGVVSSAEKRVIEINQS--TRKSLMFEDKQITHPIHRRYEELLQDNRKLKEVIEQ 78 Query: 950 YEKNIEYVTQLEAQ----LQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTE 1005 +K+ + + Q+ + Q+Y N L +EL K+ +L+ ++ +S Sbjct: 79 LDKDNQQLKQMSGENYNLKQKYMINQAELEAAQQELAKLRSQLLMRN--SSDAESSSLVA 136 Query: 1006 QYINEINKLNALLKQKDEEIIALNQKI--NNAQV-SYMSMVSDYESKLAQFTTKLENMEE 1062 +Y +I+ + + +EI LN + QV Y+ + S YE + + + +E Sbjct: 137 RYKQDISSMTQQQIKSQQEITQLNALLTEQRKQVEEYLRIKSKYEQDIQTYKNRASTLEL 196 Query: 1063 EMQRVSKQLLDSKQH--NEELQILVREQDD-QI----KELKETKLTFEMNIPKTEGMIIS 1115 E++ V +Q + Q +Q L R Q + Q+ KE E + + K I Sbjct: 197 EIRSVKEQRNSTTQSEITRLMQELARHQSEAQVRTSDKEFYERTIQTLKDKIKEMDNDIQ 256 Query: 1116 STIEPMSDDANNVDXXXXXXXXXXXXL--KVQEEEEFIQER-SVLQEQSAKLNTELQECY 1172 IE + + ++ ++++E F Q + QE+ + +E Sbjct: 257 ILIEAHNQNQFKLESAMAESKGNMQYEIDQLRQEVNFYQTQCKQWQEKCQVFELQKEESE 316 Query: 1173 TKIIQLE-TLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQR 1231 +IIQ+E +N ++ E+I + ++ + E +N +L + R Sbjct: 317 RRIIQMEIRVNETKKQIELQQNERIQRDSWQVHTIQNELENWKQKYIQLEIKTKDSETHR 376 Query: 1232 GFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTME- 1290 I +L Q+ R + ++ + EL + ++ F+S EQ S TQ E T+E Sbjct: 377 -LRIKQLEDQNNHLR-IENERVKEELDILVTEFKSIQEQNNGYRLSITQLEKQSKSTVEL 434 Query: 1291 -----QVTSLQNKLQDKEEHLRNL--------QEKYADVIN----QIEILRSEIEDEKVA 1333 QV L ++ + + ++ L QEK ++ + Q E + E EK+ Sbjct: 435 DRYKTQVNQLNQQINNYKVEIKQLQEQMIVQQQEKRIEIQSYTQYQYEAENHQKEIEKLR 494 Query: 1334 FXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXX 1393 L E ++Q+Q Q + + +S Sbjct: 495 REFRQIEQLYNEMEVQVKLWKEKFYHEQLQHQEARQLLIDVKTQYESHTYILTQTEQDKH 554 Query: 1394 RVNDAEAKVLELTHQ---LELKDSEIYQKTHEYTIT---LTQRNDEFENVRQQLVEYEKR 1447 R+ E +++EL + L++++ ++ Y++T + Q D+ VRQ E Sbjct: 555 RIQQLELQLIELQEEVRVLQIREETYKEQISTYSVTIENIKQNQDQSRKVRQ----LELD 610 Query: 1448 IEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAE 1507 IE L +S+ L ++ + N + ++ E E+++ K+ E +K + V L K+ E Sbjct: 611 IETL----KSKCRDLEKQLLDKRNEFNLLKSEWELDKQKITE---LKASNDVLL-KRKPE 662 Query: 1508 LNKALEEEVAKTNEMQTALENQEIEIVTLNDE 1539 + K + E +K +++ Q++ ++ L + Sbjct: 663 IVKQIIETPSKQEKLKIQELEQQVSLLKLQSQ 694 Score = 70.5 bits (165), Expect = 4e-10 Identities = 147/786 (18%), Positives = 336/786 (42%), Gaps = 67/786 (8%) Query: 826 RLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANR 885 R L+ +R +++ + +++ +N++L++ + Q I+ ++++ L + ++ Sbjct: 61 RYEELLQDNRKLKEVIEQLDKDNQQLKQMSGENYNLKQKYMINQAELEAAQQELAKLRSQ 120 Query: 886 TDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKV 945 + S + + + + ++ +T + Q Q+ ++ L E Q+E +R K Sbjct: 121 LLMRNSSDAESSSLVARYKQDISSMTQQ-QIKSQQEITQLNALLTEQRKQVEEYLRIKS- 178 Query: 946 LNEKYEKNIEYVTQLEAQLQ-EYKNNIENLNMNVE-ELNKMNLELIDKHVQKQQTQSPDY 1003 KYE++I+ + L+ E ++ E N + E+ ++ EL +H + Q ++ D Sbjct: 179 ---KYEQDIQTYKNRASTLELEIRSVKEQRNSTTQSEITRLMQELA-RHQSEAQVRTSD- 233 Query: 1004 TEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSD------YE-SKLAQ---- 1052 E Y I L +K+ D +I L + N Q S +++ YE +L Q Sbjct: 234 KEFYERTIQTLKDKIKEMDNDIQILIEAHNQNQFKLESAMAESKGNMQYEIDQLRQEVNF 293 Query: 1053 FTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKL--------TFEM 1104 + T+ + +E+ Q Q +S++ +++I V E QI+ + ++ T + Sbjct: 294 YQTQCKQWQEKCQVFELQKEESERRIIQMEIRVNETKKQIELQQNERIQRDSWQVHTIQN 353 Query: 1105 NIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXL---KVQEEEEF-IQERSVLQEQ 1160 + + I I+ + + + + +V+EE + + E +QEQ Sbjct: 354 ELENWKQKYIQLEIKTKDSETHRLRIKQLEDQNNHLRIENERVKEELDILVTEFKSIQEQ 413 Query: 1161 SA--KLN-TELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTV 1217 + +L+ T+L++ ++L+ T++ + +NQ QIN K +++QL + ++ Sbjct: 414 NNGYRLSITQLEKQSKSTVELDRYKTQV---NQLNQ-QINNYKVEIKQLQ---EQMIVQQ 466 Query: 1218 AELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTE---HELRVQLSAFESKY--EQLL 1272 E R I S Q +E AE ++ + + +F++ E +E+ VQ+ ++ K+ EQL Sbjct: 467 QEKRIEIQSYT-QYQYE-AENHQKEIEKLRREFRQIEQLYNEMEVQVKLWKEKFYHEQLQ 524 Query: 1273 DS------VQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSE 1326 + TQ E++ + + Q ++++Q E L LQE+ + + E + + Sbjct: 525 HQEARQLLIDVKTQYESHTYI-LTQTEQDKHRIQQLELQLIELQEEVRVLQIREETYKEQ 583 Query: 1327 IEDEKVAFXXXXXXXXXXXXXXXX--DLRTENQSYKQMQEQSILNINEENAQLKKSSXXX 1384 I V D+ T + +++Q + NE N L KS Sbjct: 584 ISTYSVTIENIKQNQDQSRKVRQLELDIETLKSKCRDLEKQLLDKRNEFN--LLKSEWEL 641 Query: 1385 XXXXXXXXXRVNDAEAK----VLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQ 1440 ND K +++ + K ++ + E ++L + + + +Q Sbjct: 642 DKQKITELKASNDVLLKRKPEIVKQIIETPSKQEKLKIQELEQQVSLLKLQSQQVSASKQ 701 Query: 1441 LVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVS 1500 V E E + + ++ ++ + E ++T E + + +++ E ++ +S S Sbjct: 702 EVIRETIRETVQVRSQEDIKLIA-NLEEELQLWKTKYYELDRRKNQVVVETIREVQQSES 760 Query: 1501 LNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSF 1560 ++ EL +++ AK E+ Q +E+ D+I Q ++ ++ +++ + Sbjct: 761 DKLRIQELEHQVKQSSAKKQEIIREFITQTVEVPVEADKIRIQQLEIQVNN--LRQEIYL 818 Query: 1561 ASDTKQ 1566 + KQ Sbjct: 819 LNQRKQ 824 Score = 68.9 bits (161), Expect = 1e-09 Identities = 146/845 (17%), Positives = 345/845 (40%), Gaps = 59/845 (6%) Query: 730 EKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVME 789 +++ E L K N + + + + K +E + EL+K +S++ S A Sbjct: 73 KEVIEQLDKDNQQLKQMSGENYNLKQKYMINQAELEAAQQELAKLRSQLLMRNSSDA--- 129 Query: 790 DRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIE-HEN 848 + + R + S Q++ K+ E T L + + ++ R+ K +I+ ++N Sbjct: 130 ESSSLVARYKQDISSMTQQQIKSQQEITQLNALLTEQRKQVEEYLRIKSKYEQDIQTYKN 189 Query: 849 KELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLK 908 + + +I + Q + S++ + L + + S+ Y+ ++ L+ +K Sbjct: 190 RASTLELEIRSVKEQRNSTTQSEITRLMQELARHQSEAQVRTSDKEFYERTIQTLKDKIK 249 Query: 909 RITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYK 968 + ++ Q LI + LE + ES + +++ ++ Y TQ + Q QE K Sbjct: 250 EMDNDIQILIEAHNQNQFKLE---SAMAESKGNMQYEIDQLRQEVNFYQTQCK-QWQE-K 304 Query: 969 NNIENLNMNVEELNKMNLELIDKHVQKQ-QTQSPDYTEQYINEINKLNALLKQKDEEIIA 1027 + L E + +E+ +KQ + Q + ++ +++ + L+ ++ I Sbjct: 305 CQVFELQKEESERRIIQMEIRVNETKKQIELQQNERIQRDSWQVHTIQNELENWKQKYIQ 364 Query: 1028 LNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVRE 1087 L K +++ ++ + E + + E ++EE+ + + ++ N ++ + + Sbjct: 365 LEIKTKDSE-THRLRIKQLEDQNNHLRIENERVKEELDILVTEFKSIQEQNNGYRLSITQ 423 Query: 1088 QDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEE 1147 + K++K T E++ KT+ + ++ NN + VQ++ Sbjct: 424 LE------KQSKSTVELDRYKTQ-------VNQLNQQINNYKVEIKQLQEQ---MIVQQQ 467 Query: 1148 EEFIQERSVLQEQSAKLN--TELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKL-- 1203 E+ I+ +S Q Q N E+++ + Q+E L E+ + Q+ K K Sbjct: 468 EKRIEIQSYTQYQYEAENHQKEIEKLRREFRQIEQLYNEM-------EVQVKLWKEKFYH 520 Query: 1204 EQL-NTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLS 1262 EQL + E LL V S + + Q E K + Q E + + E+RV L Sbjct: 521 EQLQHQEARQLLIDVKTQYESHTYILTQ-----TEQDKHRIQQLELQLIELQEEVRV-LQ 574 Query: 1263 AFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEI 1322 E Y++ + + + + +V L+ ++ + R+L+++ D N+ + Sbjct: 575 IREETYKEQISTYSVTIENIKQNQDQSRKVRQLELDIETLKSKCRDLEKQLLDKRNEFNL 634 Query: 1323 LRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSX 1382 L+SE E +K ++ ++ + ++ I + ++ + LK S Sbjct: 635 LKSEWELDKQKITELKASNDVLLKRKPEIVKQIIETPSKQEKLKIQELEQQVSLLKLQSQ 694 Query: 1383 XXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLV 1442 + + + +++ Q ++K + E + E + + Q+V Sbjct: 695 QVSASKQEV---IRETIRETVQVRSQEDIK---LIANLEEELQLWKTKYYELDRRKNQVV 748 Query: 1443 EYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKI-TESVSL 1501 +E + ++SE LR++ E+ + +K+ EI R + + + V + + + + Sbjct: 749 -----VETIREVQQSESDKLRIQELEHQVKQSSAKKQ-EIIREFITQTVEVPVEADKIRI 802 Query: 1502 NKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFA 1561 + ++N L +E+ N+ + + Q+I + + + + + K++ + F Sbjct: 803 QQLEIQVNN-LRQEIYLLNQRKQEVITQQITVEVPSQADRQIIQQLESEIVKLKTQLEFV 861 Query: 1562 SDTKQ 1566 S +KQ Sbjct: 862 SKSKQ 866 >UniRef50_A0CTT0 Cluster: Chromosome undetermined scaffold_27, whole genome shotgun sequence; n=1; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_27, whole genome shotgun sequence - Paramecium tetraurelia Length = 1028 Score = 123 bits (296), Expect = 5e-26 Identities = 194/941 (20%), Positives = 411/941 (43%), Gaps = 87/941 (9%) Query: 476 NEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVK---SN 532 N++ K +LKQ + N L ++ + A +QI + +ID NK + ++ S+ Sbjct: 73 NDLVKYINELKQSSGGTLDQFN--QLKKQYEEALQQINKQKIDIDELNKRIRSLEQELSD 130 Query: 533 HKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQK----VAELEEEKGNLQLHLVDY 588 K K Q+ +T+ K++D+ K+ ++L K + + + + L +D+ Sbjct: 131 AKSKYGQVDQTLPQ--KLADAEKKWKEFESLYNNLKLKYDTDIRDWQLKYDELNRKALDW 188 Query: 589 DSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADIS 648 + I + ++M +M++ E L++ Q D ++E + Q +D + L Sbjct: 189 ERRYGI---LEQQMKQMQDDHELELRSSGDSAKQYEDQLREWELKQNDWDNKQKAL---- 241 Query: 649 QLQSDQVCSEIKSVHLE-EQIDA-LSASKKELALVIENLKLDKEQLYGTIKDLENDKEDI 706 + + D++ +K+ E E++ A L A+++EL L+ + +Q G+ K E + + Sbjct: 242 RAEQDRLNQLLKNKDDEYERLKAQLLAAQRELDDYKNKLR-ESDQASGS-KFTEYESKIA 299 Query: 707 MNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIEN 766 +LQN Q N DL ++L+K + + + L ++ + QS+ D+K+ E N Sbjct: 300 ELRLQNQ-QLNQDL-ERLKKRYQD-LEDQLNRLQSQNQSQ-------DSKVSELQSKCGN 349 Query: 767 IESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNR 826 +E+E+ K + + E+ I ++ ++ LE++ +L E + ++ ++ Sbjct: 350 LENEVEKLNNDLRDKEQEITKLQGKQMQLEQRNKELTD----------ENNLLRKKVADQ 399 Query: 827 LAVLMDHDRVVEKQLLEIEHENKEL---QKKNQILLEENQNLQISLSDMQQHYNALVEKA 883 A + + + +++ EIE+ N L ++N+ LL + +LQ L D + +Y L E Sbjct: 400 KAEIERLELELRQKISEIEYYNLNLVNQDERNKQLLNQVDDLQFQLQDFKTNYQQLEEDF 459 Query: 884 NRTDLAESESTKYQTQLRDLE-SNLKRITHEHQTLIVQKKKEIEDLEIE---FNTQIESA 939 NR ++E + + L E +K I + + +++I LEIE F QIE Sbjct: 460 NRLQ-KKNEDLENKCALFSAEIDRMKNIIKLKNQDLEKLRRQIGSLEIEKKFFEQQIEDL 518 Query: 940 IRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMN--LELIDKHVQKQQ 997 + K + ++ K E + + QLQ+ N I +LN + E+ + + DK + + Sbjct: 519 LNKMKQMQDEIVKLNELLKERLKQLQQQNNTIISLNHQLGEMKALQTYCDQQDKRINETT 578 Query: 998 TQSPD------YTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYE---- 1047 + + + + + I+ L A +++++++ LN +I Q ++ + + + Sbjct: 579 NKLNEALLQLQFKDIELMNISALQASIQEREKQAELLNNEIVRLQNDIINKLKESDDQKE 638 Query: 1048 --SKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETK----LT 1101 KL +L+ E+ + + ++L ++ + L+ + ++Q+ +++ +T Sbjct: 639 QIKKLNDEIARLKTQEQNLHDIERKLQNAVEEINRLESQKSDLENQVSVNRQSSPKHTIT 698 Query: 1102 FEMNIPKTEGMIISSTIEPMSDDAN----NVDXXXXXXXXXXXXLKVQEEEEFIQERSVL 1157 E+ I KT + ++ I+ + D +D LK E++I +VL Sbjct: 699 KEIRIEKTSVQVDTTEIDKLKQDLRQKQFELDQLNNQLLISQNALK--SAEDYI---AVL 753 Query: 1158 QEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTV 1217 + LN E ++ QLE + + T Q+++ L+ +L Q +N+ +L Sbjct: 754 LNRINILNKENEDMLQGKQQLE-IQVQDTR---TLQDKLQNLEKQLTQFRNDNERILREF 809 Query: 1218 AELRSSISSAVDQRGFEIAELWKQHLAQRE--ADFQKTEHELRVQLSAFESKYEQLLDSV 1275 E S D +I++L Q RE A ++ E++L + E QL + Sbjct: 810 KEK----SKLYDDARQKISKLEAQATEARELQAKLREIENKLVFAQTNQERLTAQLAEKT 865 Query: 1276 QSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFX 1335 + + + N + ++T L +LQ E R L+E+ ++ + L + +V Sbjct: 866 EENNNLKQNLQIANNEITKLSEQLQQLSEQERLLKEQVNHLLQDKDALDNLKRQHEVLIA 925 Query: 1336 XXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQ 1376 +NQ + QE L I +E + Sbjct: 926 DISKANQNIDQLSIERDSLDNQLKQNQQELEKLRILQEKVR 966 Score = 88.2 bits (209), Expect = 2e-15 Identities = 138/738 (18%), Positives = 304/738 (41%), Gaps = 57/738 (7%) Query: 844 IEHENKELQKKNQI----LLEENQNLQISLSDMQQHYNALVEKANRT-DLAESESTKYQT 898 + +E K L K ++ L EN L +D+ ++ N L + + T D +Y+ Sbjct: 43 VSNERKWLGKNPEVVCFLLALENDRLVRENNDLVKYINELKQSSGGTLDQFNQLKKQYEE 102 Query: 899 QLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVT 958 L+ + K E I ++E+ D + ++ Q++ + K EK K E + Sbjct: 103 ALQQINKQ-KIDIDELNKRIRSLEQELSDAKSKYG-QVDQTLPQKLADAEKKWKEFESLY 160 Query: 959 QLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALL 1018 +L+ Y +I + + +ELN+ L+ ++ +Q Q + + E+ Sbjct: 161 N-NLKLK-YDTDIRDWQLKYDELNRKALDWERRYGILEQ-QMKQMQDDHELELRSSGDSA 217 Query: 1019 KQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHN 1078 KQ ++++ K N+ ++ ++ + +L Q L+N ++E +R+ QLL +++ Sbjct: 218 KQYEDQLREWELKQNDWDNKQKALRAE-QDRLNQL---LKNKDDEYERLKAQLLAAQREL 273 Query: 1079 EELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXX 1138 ++ + +RE D Q K T+ ++ + + ++ +E + +++ Sbjct: 274 DDYKNKLRESD-QASGSKFTEYESKIAELRLQNQQLNQDLERLKKRYQDLEDQLNRLQSQ 332 Query: 1139 XXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQ 1198 + + E + L+ + KLN +L++ +I +L+ +L + ++ N Sbjct: 333 NQS-QDSKVSELQSKCGNLENEVEKLNNDLRDKEQEITKLQGKQMQLEQRNKELTDENNL 391 Query: 1199 LKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELR 1258 L+ K+ E + L ELR IS E L + +R +L+ Sbjct: 392 LRKKVADQKAEIERL---ELELRQKISE------IEYYNLNLVNQDERNKQLLNQVDDLQ 442 Query: 1259 VQLSAFESKYEQL---LDSVQSSTQEETNKIVTME-QVTSLQNKLQDKEEHLRNLQEKYA 1314 QL F++ Y+QL + +Q ++ NK ++ ++N ++ K + L L+ + Sbjct: 443 FQLQDFKTNYQQLEEDFNRLQKKNEDLENKCALFSAEIDRMKNIIKLKNQDLEKLRRQIG 502 Query: 1315 DVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEEN 1374 + + + +IED +L E Q Q +I+++N + Sbjct: 503 SLEIEKKFFEQQIED-----LLNKMKQMQDEIVKLNELLKERLKQLQQQNNTIISLNHQL 557 Query: 1375 AQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEF 1434 ++K R+N+ K+ E QL+ KD E+ ++ +R + Sbjct: 558 GEMK----ALQTYCDQQDKRINETTNKLNEALLQLQFKDIEL-MNISALQASIQEREKQA 612 Query: 1435 ENVRQQLVEYEKRIEDLTYEKESELA--------ILRLKMHENANHYETMQKESEIERVK 1486 E + ++V + I + E + + I RLK E H + ++ +E + Sbjct: 613 ELLNNEIVRLQNDIINKLKESDDQKEQIKKLNDEIARLKTQEQNLHDIERKLQNAVEEIN 672 Query: 1487 LIEELNVKITESVSLNKQVAELNKALEE-EVAKT---------NEMQTALENQEIEIVTL 1536 +E + VS+N+Q + + +E + KT ++++ L ++ E+ L Sbjct: 673 RLESQKSDLENQVSVNRQSSPKHTITKEIRIEKTSVQVDTTEIDKLKQDLRQKQFELDQL 732 Query: 1537 NDEITNLQNMVRASSSKI 1554 N+++ QN ++++ I Sbjct: 733 NNQLLISQNALKSAEDYI 750 Score = 85.4 bits (202), Expect = 1e-14 Identities = 166/813 (20%), Positives = 343/813 (42%), Gaps = 71/813 (8%) Query: 147 LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXX 206 L+ +K KD+ L+ ++ + + D + K+ E DQ A+ Sbjct: 248 LNQLLKNKDDEYERLKAQLLAAQRELDDYKNKLRESDQ-------ASGSKFTEYESKIAE 300 Query: 207 XXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFE 266 + Q + ++++ + +E D+ RL +S+D ++S L+ LE + Sbjct: 301 LRLQNQQLNQDLERLKKRYQDLE----DQLNRLQSQNQSQDSKVSELQSKCGNLENEVEK 356 Query: 267 ISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTK 326 ++ + QE+ + L ++ + K ++K +E + EL + Sbjct: 357 LNNDLRDKEQEITKLQGKQMQLEQRNKELTDEN---NLLRKKVADQKAEIERLEL-ELRQ 412 Query: 327 KIELLEHLNCQI---RQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMK 383 KI +E+ N + + NK+L N++ + + + + ++ +R +N + K Sbjct: 413 KISEIEYYNLNLVNQDERNKQLLNQVDDLQFQLQDFKTNYQQLEEDFNRLQKKNEDLENK 472 Query: 384 SPWSQLSSETL-------NQDTDK---KINKNEIAK--LEMVIQSL-NKDLVDKEYVISE 430 + + NQD +K +I EI K E I+ L NK ++ ++ Sbjct: 473 CALFSAEIDRMKNIIKLKNQDLEKLRRQIGSLEIEKKFFEQQIEDLLNKMKQMQDEIVKL 532 Query: 431 KDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIA-KVQEQLKQEL 489 + +T+I+ L HQ + + +NE K+ E L Q Sbjct: 533 NELLKERLKQLQQQNNTIIS---LNHQLGEMKALQTYCDQQDKRINETTNKLNEALLQLQ 589 Query: 490 NDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSK 549 +I+ +N+ L ++ E+Q LN+EI ++I KLK+ + K Sbjct: 590 FKDIELMNISALQASIQEREKQAELLNNEIVRLQNDIIN-------KLKESDDQKEQIKK 642 Query: 550 VSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMI-ESDVYKKMIEMENL 608 ++D + + LH + +K+ EE L+ D ++ + K I E Sbjct: 643 LNDEIARLKTQEQNLHDIERKLQNAVEEINRLESQKSDLENQVSVNRQSSPKHTITKEIR 702 Query: 609 AETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQ--LQS--DQVCSEIKSVH- 663 E + E K L Q+L Q + D++ ++L ISQ L+S D + + ++ Sbjct: 703 IEKTSVQVDTTEIDK--LKQDLRQKQFELDQLNNQLL-ISQNALKSAEDYIAVLLNRINI 759 Query: 664 LEEQIDALSASKKELALVIENLKLDKEQLYGTIKDL---ENDKEDIMNKLQNYIQENMDL 720 L ++ + + K++L + +++ + +++L K L ND E I+ + + + D Sbjct: 760 LNKENEDMLQGKQQLEIQVQDTRTLQDKLQNLEKQLTQFRNDNERILREFKEKSKLYDDA 819 Query: 721 TDKLEKMSAE--KISELLAKINHEEQSKI--QT-QFGIDAKIQERDLYIENIESELSKYK 775 K+ K+ A+ + EL AK+ E + QT Q + A++ E+ N++ L Sbjct: 820 RQKISKLEAQATEARELQAKLREIENKLVFAQTNQERLTAQLAEKTEENNNLKQNLQIAN 879 Query: 776 SRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDR 835 + I +L E + + ++ L+ +Q+ LQ+K A Q + L+ A + ++ Sbjct: 880 NEITKLSEQLQQLSEQERLLK---EQVNHLLQDKD-ALDNLKRQHEVLI---ADISKANQ 932 Query: 836 VVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTK 895 +++ +E + + +L K+NQ LE+ + LQ + + N L +K R AE+E Sbjct: 933 NIDQLSIERDSLDNQL-KQNQQELEKLRILQEKVRFLGGECNKLNDKLGR---AENELDN 988 Query: 896 YQTQLRDLESNLKRITHEHQTLIVQKKKEIEDL 928 ++ + ++ S+L + + I + KE+E+L Sbjct: 989 FRKRGQE-NSDLNKQIIDKNGQIERLNKELENL 1020 Score = 83.0 bits (196), Expect = 6e-14 Identities = 131/686 (19%), Positives = 293/686 (42%), Gaps = 71/686 (10%) Query: 944 KVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDY 1003 K +NE + + + Q ++Y+ ++ +N K++++ ++K ++ + + D Sbjct: 77 KYINELKQSSGGTLDQFNQLKKQYEEALQQINKQ-----KIDIDELNKRIRSLEQELSDA 131 Query: 1004 TEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEE 1063 +Y L L +++ NN ++ Y + + D++ K + K + E Sbjct: 132 KSKYGQVDQTLPQKLADAEKKWKEFESLYNNLKLKYDTDIRDWQLKYDELNRKALDWERR 191 Query: 1064 MQRVSKQLLDSKQHNEELQIL-----VREQDDQIKE--LKETKLTFEMNIPKTEGMIISS 1116 + +Q + Q + EL++ ++ +DQ++E LK+ + + E ++ Sbjct: 192 YG-ILEQQMKQMQDDHELELRSSGDSAKQYEDQLREWELKQNDWDNKQKALRAEQDRLNQ 250 Query: 1117 TIEPMSDDANNVDXXXXXXXXXXXXLK--VQEEEE-----FIQERSVLQE---QSAKLNT 1166 ++ D+ + K ++E ++ F + S + E Q+ +LN Sbjct: 251 LLKNKDDEYERLKAQLLAAQRELDDYKNKLRESDQASGSKFTEYESKIAELRLQNQQLNQ 310 Query: 1167 ELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISS 1226 +L+ + LE L + ++++L+SK L E + L + + + I+ Sbjct: 311 DLERLKKRYQDLEDQLNRLQSQNQSQDSKVSELQSKCGNLENEVEKLNNDLRDKEQEITK 370 Query: 1227 A------VDQRGFEIAE---LWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQS 1277 ++QR E+ + L ++ +A ++A+ ++ E ELR ++S E L++ Sbjct: 371 LQGKQMQLEQRNKELTDENNLLRKKVADQKAEIERLELELRQKISEIEYYNLNLVN---- 426 Query: 1278 STQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXX 1337 Q+E NK + + QV LQ +LQD + + + L+E + N+++ ++E++ F Sbjct: 427 --QDERNKQL-LNQVDDLQFQLQDFKTNYQQLEEDF----NRLQKKNEDLENKCALFSAE 479 Query: 1338 XXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVND 1397 ++ +NQ ++++ Q I ++ E KK ++ D Sbjct: 480 IDRMKNI-------IKLKNQDLEKLRRQ-IGSLEIE----KKFFEQQIEDLLNKMKQMQD 527 Query: 1398 AEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKES 1457 K+ EL + LK Q+ + I+L + E + ++ + +KRI + T + Sbjct: 528 EIVKLNELLKE-RLKQ---LQQQNNTIISLNHQLGEMKALQTYCDQQDKRINETTNKLNE 583 Query: 1458 ELAILRLKMHENAN------HYETMQKESEI---ERVKLIEELNVKITESVSLNKQVAEL 1508 L L+ K E N + +K++E+ E V+L ++ K+ ES +Q+ +L Sbjct: 584 ALLQLQFKDIELMNISALQASIQEREKQAELLNNEIVRLQNDIINKLKESDDQKEQIKKL 643 Query: 1509 NKA---LEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTK 1565 N L+ + ++++ L+N EI L + ++L+N V + KH Sbjct: 644 NDEIARLKTQEQNLHDIERKLQNAVEEINRLESQKSDLENQVSVNRQSSPKHTITKEIRI 703 Query: 1566 QGRDEQLDNTMNKELLDAVPRAELDL 1591 + Q+D T +L + + + +L Sbjct: 704 EKTSVQVDTTEIDKLKQDLRQKQFEL 729 Score = 50.4 bits (115), Expect = 4e-04 Identities = 64/362 (17%), Positives = 146/362 (40%), Gaps = 22/362 (6%) Query: 1238 LWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQN 1297 L L + D K +EL+ ++ QL + + Q+ + + +++ L Sbjct: 63 LENDRLVRENNDLVKYINELKQSSGGTLDQFNQLKKQYEEALQQINKQKIDIDE---LNK 119 Query: 1298 KLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXD--LRTE 1355 +++ E+ L + + KY V + ++ E + F D L+ + Sbjct: 120 RIRSLEQELSDAKSKYGQVDQTLPQKLADAEKKWKEFESLYNNLKLKYDTDIRDWQLKYD 179 Query: 1356 NQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELT-HQLELKDS 1414 + K + + I E+ + + + + + + EL + + K Sbjct: 180 ELNRKALDWERRYGILEQQMKQMQDDHELELRSSGDSAKQYEDQLREWELKQNDWDNKQK 239 Query: 1415 EIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYE-KESELAILRLKMHENANHY 1473 + + L ++DE+E ++ QL+ ++ ++D + +ES+ A Y Sbjct: 240 ALRAEQDRLNQLLKNKDDEYERLKAQLLAAQRELDDYKNKLRESDQA-----SGSKFTEY 294 Query: 1474 ETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEI 1533 E+ E ++ +L ++L L Q+ L + + +K +E+Q+ N E E+ Sbjct: 295 ESKIAELRLQNQQLNQDLERLKKRYQDLEDQLNRLQSQNQSQDSKVSELQSKCGNLENEV 354 Query: 1534 VTLNDEITNLQNMVRASSSKIQ-KHVSFASDTKQGRDEQLDNTMNKELLD---AVPRAEL 1589 LN+++ + + + +K+Q K + K+ DE +N + K++ D + R EL Sbjct: 355 EKLNNDLRDKEQEI----TKLQGKQMQLEQRNKELTDE--NNLLRKKVADQKAEIERLEL 408 Query: 1590 DL 1591 +L Sbjct: 409 EL 410 Score = 40.7 bits (91), Expect = 0.32 Identities = 79/440 (17%), Positives = 180/440 (40%), Gaps = 24/440 (5%) Query: 140 QLGDVTHLSNTIKEKDNALSVLQVKMKIMETTILD-LQEKINEKDQIIEAKNKATTXXXX 198 +L +++ L +I+E++ +L ++ ++ I++ L+E ++K+QI + ++ Sbjct: 594 ELMNISALQASIQEREKQAELLNNEIVRLQNDIINKLKESDDQKEQIKKLNDEIARLKTQ 653 Query: 199 XXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLE---- 254 ++ +++ +++ +E + +Q K +K++RI Sbjct: 654 EQNLHDIERKL--QNAVEEINRLESQKSDLENQVSVNRQSSPKHTITKEIRIEKTSVQVD 711 Query: 255 --EANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEE 312 E +KL + R + E +L +L L + + E + ++ Sbjct: 712 TTEIDKLKQDLR-QKQFELDQLNNQLLISQNALKSAEDYIAVLLNRINILNKENEDMLQG 770 Query: 313 KGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISR 372 K LEI T + + L++L Q+ Q + E L +SK +K S L ++ Sbjct: 771 KQQLEIQVQDTRTLQ-DKLQNLEKQLTQFRNDNERILREFKEKSKLYDDARQKISKLEAQ 829 Query: 373 KS-GRNTASKM-----KSPWSQLSSETLNQDTDKKINKNEIAK--LEMVIQSLNKDLVDK 424 + R +K+ K ++Q + E L +K +N K L++ + K L ++ Sbjct: 830 ATEARELQAKLREIENKLVFAQTNQERLTAQLAEKTEENNNLKQNLQIANNEITK-LSEQ 888 Query: 425 EYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQ 484 +SE++ + L+ +H+ + S + + + E + Q Sbjct: 889 LQQLSEQERLLKEQVNHLLQDKDALDNLKRQHEVLIADISKANQNIDQLSI-ERDSLDNQ 947 Query: 485 LKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTI 544 LKQ E++ + + L EK++ + +LND++ A + + + ++ I Sbjct: 948 LKQN-QQELEKLRI--LQEKVRFLGGECNKLNDKLGRAENELDNFRKRGQENSDLNKQII 1004 Query: 545 DNFSKVSDSNKEIVRLTEEL 564 D ++ NKE+ L ++L Sbjct: 1005 DKNGQIERLNKELENLRKQL 1024 >UniRef50_P08799 Cluster: Myosin-2 heavy chain, non muscle; n=5; Dictyostelium discoideum|Rep: Myosin-2 heavy chain, non muscle - Dictyostelium discoideum (Slime mold) Length = 2116 Score = 123 bits (296), Expect = 5e-26 Identities = 231/1245 (18%), Positives = 508/1245 (40%), Gaps = 79/1245 (6%) Query: 297 KQSIEPSCEEKTEIE-EKGSLEIA--NM-TELTKKIELLEHLNCQIRQTNKELENKLATM 352 K++++ + K +E +K LEI +M +EL +K LE+L Q R +++ + + Sbjct: 876 KETLKAMYDSKDALEAQKRELEIRVEDMESELDEKKLALENLQNQKRSVEEKVRDLEEEL 935 Query: 353 GTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEM 412 E K ++ K +K +MK S + K + E+ +L Sbjct: 936 QEEQKLRNTLEKL------KKKYEEELEEMKRVNDGQSDTISRLEKIKDELQKEVEELTE 989 Query: 413 VIQSLNKD--LVDKEYVI--SEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHV 468 +KD +++K V SE D K L+ Q + ++ + + Sbjct: 990 SFSEESKDKGVLEKTRVRLQSELDDLTVRLDSETKDKSELLRQKKKLEEELKQVQEALAA 1049 Query: 469 GTNTEDVNEIAKVQEQLKQ-ELNDEIK-DVNVKDLIEKLKSA-EEQITQLNDEIDAANKN 525 T + E A + Q + ELN++ +V + +EK K E Q+ +N+E+D KN Sbjct: 1050 ETAAKLAQEAANKKLQGEYTELNEKFNSEVTARSNVEKSKKTLESQLVAVNNELDEEKKN 1109 Query: 526 MIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEI----VRLTEELHHLSQKVAELEEEKGNL 581 ++ K +++ D K + V+ ++ L +++EL+ L Sbjct: 1110 RDALEKKKKALDAMLEEMKDQLESTGGEKKSLYDLKVKQESDMEALRNQISELQSTIAKL 1169 Query: 582 QL--HLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDE 639 + ++ + R+ + ++ + + N+ + + K LE + L +E +Q D+ Sbjct: 1170 EKIKSTLEGEVARL-QGELEAEQLAKSNVEKQKKKVELDLEDKSAQLAEET-AAKQALDK 1227 Query: 640 VEDKLA-DISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKD 698 ++ KL ++S++Q+ + K+V+ + L S L L +E + K+ L Sbjct: 1228 LKKKLEQELSEVQTQLSEANNKNVNSDSTNKHLETSFNNLKLELEAEQKAKQALEKKRLG 1287 Query: 699 LENDKEDIMNKLQNYIQENMDLTDKLEKMSAEK-ISELLAKINHEEQSKIQTQFGIDAKI 757 LE++ + + +L+ ++ +++ K+ EK +SEL +I E SK + K Sbjct: 1288 LESELKHVNEQLEE--EKKQKESNEKRKVDLEKEVSELKDQIEEEVASKKAVTEAKNKKE 1345 Query: 758 QERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYT 817 E D +S + +L+ A E+ R + E QL + K+KA + Sbjct: 1346 SELDEIKRQYADVVSSRDKSVEQLKTLQAKNEELRNTAEEAEGQLDRAERSKKKAEFDLE 1405 Query: 818 IQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYN 877 L A + ++ ++K + EL + E+ ++ ++ + + Sbjct: 1406 EAVKNLEEETAKKVKAEKAMKKAETDYRSTKSELDDAKNVSSEQYVQIKRLNEELSELRS 1465 Query: 878 ALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIE 937 L E R + A ++ L L+ + + + +++ ++LE+ ++E Sbjct: 1466 VLEEADERCNSAIKAKKTAESALESLKDEIDAANNAK----AKAERKSKELEVRV-AELE 1520 Query: 938 SAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQ 997 ++ DK N+E++ + +A++ + + ++ E +++ + K+ +KQ Sbjct: 1521 ESLEDKSGT-----VNVEFIRKKDAEIDDLRARLDR-----ETESRIKSDEDKKNTRKQF 1570 Query: 998 TQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKL 1057 E+ E+ ++ L K+ + +II L+ +++ S + + + KL Q + Sbjct: 1571 ADLEAKVEEAQREVVTIDRLKKKLESDIIDLSTQLDTETKSRIK-IEKSKKKLEQTLAER 1629 Query: 1058 ENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIK-ELKETKLTFEMNIPKTEGMI--I 1114 EE SK +EE++ V ++ D+++ +L + + K + ++ + Sbjct: 1630 RAAEEG---------SSKAADEEIRKQVWQEVDELRAQLDSERAALNASEKKIKSLVAEV 1680 Query: 1115 SSTIEPMSDDANNVDXXXXXXXXXXXXLK-VQEE-EEFIQERSVLQEQSAKLNTELQECY 1172 E + D+ D L+ V+++ EE RS L++ +L TE+++ Sbjct: 1681 DEVKEQLEDEILAKDKLVKAKRALEVELEEVRDQLEEEEDSRSELEDSKRRLTTEVEDIK 1740 Query: 1173 TKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRG 1232 K NT+L + ++ LK +LE + + L S + + Sbjct: 1741 KKYDAEVEQNTKLDEAKKKLTDDVDTLKKQLEDEKKKLNESERAKKRLESENEDFLAKLD 1800 Query: 1233 FEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQV 1292 E+ ++ ++ E D +K E +L+ ++KY+ L D + TQ E +Q+ Sbjct: 1801 AEV-----KNRSRAEKDRKKYEKDLK------DTKYK-LNDEAATKTQTEIGAAKLEDQI 1848 Query: 1293 TSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDE-KVAF-XXXXXXXXXXXXXXXX 1350 L++KL+ ++ + + +I+ LR++IEDE K+ Sbjct: 1849 DELRSKLEQEQAKATQADKSKKTLEGEIDNLRAQIEDEGKIKMRLEKEKRALEGELEELR 1908 Query: 1351 DLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLE 1410 + E + K EQS + E +++ ++ + +++E +LE Sbjct: 1909 ETVEEAEDSKSEAEQSKRLVELELEDARRNLQKEIDAKEIAEDAKSNLQREIVEAKGRLE 1968 Query: 1411 LK-----DSEIYQKTHEYTI-TLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRL 1464 + +S+ +K E I LT + D + + Q ++ K+IE E + Sbjct: 1969 EESIARTNSDRSRKRLEAEIDALTAQVDAEQKAKNQQIKENKKIETELKEYRKKFGESEK 2028 Query: 1465 KMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELN 1509 + E ++ + + + + +E ++T L K ++E++ Sbjct: 2029 TKTKEFLVVEKLETDYKRAKKEAADEQQQRLTVENDLRKHLSEIS 2073 Score = 120 bits (289), Expect = 3e-25 Identities = 238/1114 (21%), Positives = 457/1114 (41%), Gaps = 116/1114 (10%) Query: 530 KSNHKLKLKQMQKTIDNF-SKVSDSNKEIVRLTEELHHLSQKVAELEE----EKGNLQLH 584 + N + ++K+ ++ I S ++DS + +L + L V +L+ EK L+ Sbjct: 823 RRNFEKEIKEKEREILELKSNLTDSTTQKDKLEKSLKDTESNVLDLQRQLKAEKETLKAM 882 Query: 585 LVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKL 644 D+ + ++ ++ +ME+ + + A+ L++QK + +++ L+++ E + Sbjct: 883 YDSKDALEAQKRELEIRVEDMESELDEKKLALENLQNQKRSVEEKVRDLEEELQEEQKLR 942 Query: 645 ADISQLQS--DQVCSEIKSVH--LEEQIDALSASKKELALVIENL-------KLDKEQLY 693 + +L+ ++ E+K V+ + I L K EL +E L DK L Sbjct: 943 NTLEKLKKKYEEELEEMKRVNDGQSDTISRLEKIKDELQKEVEELTESFSEESKDKGVLE 1002 Query: 694 GTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAE--KISELL-----AKINHE-EQS 745 T L+++ +D+ +L + ++ +L + +K+ E ++ E L AK+ E Sbjct: 1003 KTRVRLQSELDDLTVRLDSETKDKSELLRQKKKLEEELKQVQEALAAETAAKLAQEAANK 1062 Query: 746 KIQTQF-GIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGS 804 K+Q ++ ++ K N+E +S++ + + + R +LE+K L + Sbjct: 1063 KLQGEYTELNEKFNSEVTARSNVEKSKKTLESQLVAVNNELDEEKKNRDALEKKKKALDA 1122 Query: 805 YLQEKQKAYSEYTIQEDELVNRLAVLMDHD-RVVEKQLLEIEHENKELQKKNQILLEENQ 863 L+E K E T E + + L V + D + Q+ E++ +L+K L E Sbjct: 1123 MLEE-MKDQLESTGGEKKSLYDLKVKQESDMEALRNQISELQSTIAKLEKIKSTLEGEVA 1181 Query: 864 NLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKK 923 LQ L Q + K+N E + K + L D + L T Q L KKK Sbjct: 1182 RLQGELEAEQ------LAKSN----VEKQKKKVELDLEDKSAQLAEETAAKQALDKLKKK 1231 Query: 924 EIEDLEIEFNTQIESAIRDKKVLNEKYEKNIE-----YVTQLEAQLQEYKNNIENLNMNV 978 ++L E TQ+ A +K V ++ K++E +LEA+ Q+ K +E + + Sbjct: 1232 LEQELS-EVQTQLSEA-NNKNVNSDSTNKHLETSFNNLKLELEAE-QKAKQALEKKRLGL 1288 Query: 979 E-ELNKMNLELIDKHVQKQQTQSPDY-TEQYINEI-NKLNALLKQKDEEIIALNQK---I 1032 E EL +N +L ++ QK+ + E+ ++E+ +++ + K A N+K + Sbjct: 1289 ESELKHVNEQLEEEKKQKESNEKRKVDLEKEVSELKDQIEEEVASKKAVTEAKNKKESEL 1348 Query: 1033 NNAQVSYMSMVSDYESKLAQFTT---KLENMEEEMQRVSKQLLDSKQHNEELQILVREQD 1089 + + Y +VS + + Q T K E + + QL +++ ++ + + E Sbjct: 1349 DEIKRQYADVVSSRDKSVEQLKTLQAKNEELRNTAEEAEGQLDRAERSKKKAEFDLEEAV 1408 Query: 1090 DQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEE 1149 ++E K+ E + K E S+ E DDA NV + EE Sbjct: 1409 KNLEEETAKKVKAEKAMKKAETDYRSTKSE--LDDAKNVSSEQYVQIK-------RLNEE 1459 Query: 1150 FIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTE 1209 + RSVL+E + N+ ++ T LE+L E+ + N K+K E+ + E Sbjct: 1460 LSELRSVLEEADERCNSAIKAKKTAESALESLKDEI--------DAANNAKAKAERKSKE 1511 Query: 1210 NDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYE 1269 L VAEL S+ D+ G E + +++A+ +LR +L Sbjct: 1512 ---LEVRVAELEESLE---DKSGTVNVEF----IRKKDAEID----DLRARLDR------ 1551 Query: 1270 QLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIED 1329 +S + + +K T +Q L+ K+++ + + + + + I L ++++ Sbjct: 1552 ----ETESRIKSDEDKKNTRKQFADLEAKVEEAQREVVTIDRLKKKLESDIIDLSTQLDT 1607 Query: 1330 EKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXX 1389 E + E S K E+ + +E +L+ Sbjct: 1608 ETKSRIKIEKSKKKLEQTLAERRAAEEGSSKAADEEIRKQVWQEVDELRAQLDSERAALN 1667 Query: 1390 XXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIE 1449 ++ A+V E+ QLE EI K + E E VR QL E E Sbjct: 1668 ASEKKIKSLVAEVDEVKEQLE---DEILAK-DKLVKAKRALEVELEEVRDQLEEE----E 1719 Query: 1450 DLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELN 1509 D E E L ++ + Y ++E+E+ ++E K+T+ V L Sbjct: 1720 DSRSELEDSKRRLTTEVEDIKKKY-----DAEVEQNTKLDEAKKKLTDDVD------TLK 1768 Query: 1510 KALEEEVAKTNEMQTALENQEIEIVTLNDEI-TNLQNMVRASSSKIQKHVSFASDTKQGR 1568 K LE+E K NE + A + E E ++ ++N RA + +K+ DTK Sbjct: 1769 KQLEDEKKKLNESERAKKRLESENEDFLAKLDAEVKNRSRAEKDR-KKYEKDLKDTKYKL 1827 Query: 1569 DEQLDNTMNKELLDAVPRAELDLAMYMLHQRDVR 1602 +++ E+ A ++D L Q + Sbjct: 1828 NDEAATKTQTEIGAAKLEDQIDELRSKLEQEQAK 1861 Score = 102 bits (244), Expect = 9e-20 Identities = 181/955 (18%), Positives = 416/955 (43%), Gaps = 89/955 (9%) Query: 659 IKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENM 718 +K + E++I EL + + K++L ++KD E++ D+ +L+ + Sbjct: 821 LKRRNFEKEIKEKEREILELKSNLTDSTTQKDKLEKSLKDTESNVLDLQRQLKAEKETLK 880 Query: 719 DLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRI 778 + D + + A+K EL ++ +++++ E+ L +EN++++ + ++ Sbjct: 881 AMYDSKDALEAQK-RELEIRVE-----------DMESELDEKKLALENLQNQKRSVEEKV 928 Query: 779 CRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVE 838 LEE + + R +LE+ + L+E ++ + + ++RL + D ++ Sbjct: 929 RDLEEELQEEQKLRNTLEKLKKKYEEELEEMKRVND----GQSDTISRLEKIKDE---LQ 981 Query: 839 KQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQT 898 K++ E+ E K +L + LQ L D+ ++ E ++++L + K + Sbjct: 982 KEVEELTESFSEESKDKGVLEKTRVRLQSELDDLTVRLDS--ETKDKSELLR-QKKKLEE 1038 Query: 899 QLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVT 958 +L+ ++ L T KK ++ E N + S + + + EK +K Sbjct: 1039 ELKQVQEALAAETAAKLAQEAANKK-LQGEYTELNEKFNSEVTARSNV-EKSKKT----- 1091 Query: 959 QLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALL 1018 LE+QL N ++ E+ N+ LE K + + D E E L L Sbjct: 1092 -LESQLVAVNNELDE-----EKKNRDALEKKKKALDAMLEEMKDQLESTGGEKKSLYDLK 1145 Query: 1019 KQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHN 1078 +++ ++ AL +I+ Q S ++ + +S L +L+ E E ++++K ++ ++ Sbjct: 1146 VKQESDMEALRNQISELQ-STIAKLEKIKSTLEGEVARLQG-ELEAEQLAKSNVEKQKKK 1203 Query: 1079 EELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDAN----NVDXXXXX 1134 EL + ++ Q+ E K + K E + S ++ +AN N D Sbjct: 1204 VELDL--EDKSAQLAEETAAKQALDKLKKKLEQEL--SEVQTQLSEANNKNVNSDSTNKH 1259 Query: 1135 XXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQE 1194 LK++ E E + + L+++ L +EL+ ++ + + V ++ Sbjct: 1260 LETSFNNLKLELEAE-QKAKQALEKKRLGLESELKHVNEQLEEEKKQKESNEKRKVDLEK 1318 Query: 1195 QINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTE 1254 ++++LK ++E+ VA + +++ A +++ E+ E+ +Q+ AD + Sbjct: 1319 EVSELKDQIEE----------EVAS-KKAVTEAKNKKESELDEIKRQY-----ADVVSSR 1362 Query: 1255 HELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYA 1314 + QL ++K E+L +++ +E ++ E+ S + D EE ++NL+E+ A Sbjct: 1363 DKSVEQLKTLQAKNEEL----RNTAEEAEGQLDRAER--SKKKAEFDLEEAVKNLEEETA 1416 Query: 1315 DVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEEN 1374 + + E + E + + ++ N+ ++ +S+L +E Sbjct: 1417 KKV-KAEKAMKKAETDYRSTKSELDDAKNVSSEQYVQIKRLNEELSEL--RSVLEEADER 1473 Query: 1375 A----QLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTIT---- 1426 + KK++ N+A+AK + +LE++ +E+ + + + T Sbjct: 1474 CNSAIKAKKTAESALESLKDEIDAANNAKAKAERKSKELEVRVAELEESLEDKSGTVNVE 1533 Query: 1427 -LTQRNDEFENVRQQL-VEYEKRIEDLTYEKES--ELAILRLKMHENANHYET---MQKE 1479 + +++ E +++R +L E E RI+ +K + + A L K+ E T ++K+ Sbjct: 1534 FIRKKDAEIDDLRARLDRETESRIKSDEDKKNTRKQFADLEAKVEEAQREVVTIDRLKKK 1593 Query: 1480 SEIERVKLIEELNVKITESVSLNKQVAELNKAL-EEEVAKTNEMQTALENQEIEIVTLND 1538 E + + L +L+ + + + K +L + L E A+ + A E ++ D Sbjct: 1594 LESDIIDLSTQLDTETKSRIKIEKSKKKLEQTLAERRAAEEGSSKAADEEIRKQVWQEVD 1653 Query: 1539 EITNLQNMVRASSSKIQKHV-SFASDTKQGRDEQLDNTMNKELLDAVPRA-ELDL 1591 E+ + RA+ + +K + S ++ + +++ D + K+ L RA E++L Sbjct: 1654 ELRAQLDSERAALNASEKKIKSLVAEVDEVKEQLEDEILAKDKLVKAKRALEVEL 1708 Score = 100 bits (239), Expect = 4e-19 Identities = 202/1093 (18%), Positives = 433/1093 (39%), Gaps = 73/1093 (6%) Query: 69 KRIKEHRKATAELLGRPFVPGISESLANTLKQKEILMEKIKQYKELSKRSSTTIVRXXXX 128 K+++E K E L +++ AN Q E K E++ RS+ V Sbjct: 1034 KKLEEELKQVQEALAAETAAKLAQEAANKKLQGEYTELNEKFNSEVTARSN---VEKSKK 1090 Query: 129 XXXXXXXXXXXQLGDVTHLSNTIKEKDNALSVLQVKMKI-METT------ILDLQEKINE 181 +L + + +++K AL + +MK +E+T + DL K+ + Sbjct: 1091 TLESQLVAVNNELDEEKKNRDALEKKKKALDAMLEEMKDQLESTGGEKKSLYDL--KVKQ 1148 Query: 182 KDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLK 241 + + +N+ + E + Q E E + +K L Sbjct: 1149 ESDMEALRNQISELQSTIAKLEKIKSTLEGEVARLQGELEAEQLAKSNVEKQKKKVEL-- 1206 Query: 242 DIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLA----- 296 D+E K +++ A + L+ + ++ E S++ +L + L Sbjct: 1207 DLEDKSAQLAEETAAKQALDKLKKKLEQELSEVQTQLSEANNKNVNSDSTNKHLETSFNN 1266 Query: 297 -KQSIEPSCEEKTEIEEK-----GSLEIAN--MTELTKKIELLEHLNCQIRQTNKELENK 348 K +E + K +E+K L+ N + E K+ E E + + EL+++ Sbjct: 1267 LKLELEAEQKAKQALEKKRLGLESELKHVNEQLEEEKKQKESNEKRKVDLEKEVSELKDQ 1326 Query: 349 LATMGTESKAVS-SPSKKGSPL--ISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKN 405 + KAV+ + +KK S L I R+ +S+ KS + + N++ + Sbjct: 1327 IEEEVASKKAVTEAKNKKESELDEIKRQYADVVSSRDKSVEQLKTLQAKNEELRNTAEEA 1386 Query: 406 EIAKLEMVIQSLNKDLVDKEYVIS--EKDTXXXXXXXXXXGK---DTLIAQLQLEHQQHM 460 E +L+ +S K D E + E++T K D + +L+ +++ Sbjct: 1387 E-GQLDRAERSKKKAEFDLEEAVKNLEEETAKKVKAEKAMKKAETDYRSTKSELDDAKNV 1445 Query: 461 EGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEID 520 + + E+++E+ V E+ + N IK K+AE + L DEID Sbjct: 1446 SSEQYVQIKRLNEELSELRSVLEEADERCNSAIK---------AKKTAESALESLKDEID 1496 Query: 521 AANKNMIKVKSNHK---LKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEE 577 AAN K + K +++ ++++++++ K N E +R + + A L+ E Sbjct: 1497 AANNAKAKAERKSKELEVRVAELEESLED--KSGTVNVEFIRKKDA--EIDDLRARLDRE 1552 Query: 578 KGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKY 637 + D + R +D+ K+ E + T + LES DL +L + Sbjct: 1553 TESRIKSDEDKKNTRKQFADLEAKVEEAQREVVTIDRLKKKLESDIIDLSTQLDTETKSR 1612 Query: 638 DEVEDKLADISQ-LQSDQVCSEIKSVHLEEQI-DALSASKKELALVIENLKLDKEQLYGT 695 ++E + Q L + E S +E+I + EL +++ + Sbjct: 1613 IKIEKSKKKLEQTLAERRAAEEGSSKAADEEIRKQVWQEVDELRAQLDSERAALNASEKK 1672 Query: 696 IKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDA 755 IK L + +++ +L++ I L + E + E+ ++ EE S+ + + D+ Sbjct: 1673 IKSLVAEVDEVKEQLEDEILAKDKLVKAKRALEVE-LEEVRDQLEEEEDSRSELE---DS 1728 Query: 756 KIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSE 815 K + +E+I+ + + +L+E+ + D +L+++ + L E ++A Sbjct: 1729 K-RRLTTEVEDIKKKYDAEVEQNTKLDEAKKKLTDDVDTLKKQLEDEKKKLNESERAKKR 1787 Query: 816 YTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQH 875 + ++ + +L + + EK + E + K+ + K +I + ++ Sbjct: 1788 LESENEDFLAKLDAEVKNRSRAEKDRKKYEKDLKDTKYKLNDEAATKTQTEIGAAKLEDQ 1847 Query: 876 YNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQ 935 + L K + +++ K + L NL+ + + ++ +KE LE E Sbjct: 1848 IDELRSKLEQEQAKATQADKSKKTLEGEIDNLRAQIEDEGKIKMRLEKEKRALEGELEEL 1907 Query: 936 IESA--IRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHV 993 E+ D K E+ ++ +E +LE + + I+ + + + + E+++ Sbjct: 1908 RETVEEAEDSKSEAEQSKRLVE--LELEDARRNLQKEIDAKEIAEDAKSNLQREIVEAKG 1965 Query: 994 QKQQ-----TQSPDYTEQYINEINKLNALL----KQKDEEIIALNQKINNAQVSYMSMVS 1044 + ++ T S ++ EI+ L A + K K+++ I N+KI Y Sbjct: 1966 RLEEESIARTNSDRSRKRLEAEIDALTAQVDAEQKAKNQQ-IKENKKIETELKEYRKKFG 2024 Query: 1045 DYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEM 1104 + E + +E +E + +R K+ D +Q ++ +R+ +I LK+ + Sbjct: 2025 ESEKTKTKEFLVVEKLETDYKRAKKEAADEQQQRLTVENDLRKHLSEISLLKDAIDKLQR 2084 Query: 1105 NIPKTEGMIISST 1117 + KT+ + + T Sbjct: 2085 DHDKTKRELETET 2097 Score = 99.1 bits (236), Expect = 9e-19 Identities = 234/1203 (19%), Positives = 510/1203 (42%), Gaps = 113/1203 (9%) Query: 150 TIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXX 209 T+K ++ L+ + + +E + D++ +++EK +E Sbjct: 878 TLKAMYDSKDALEAQKRELEIRVEDMESELDEKKLALE--------NLQNQKRSVEEKVR 929 Query: 210 XXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISL 269 E+ Q+ K++ ++ ++++E + + + + + IS LE+ + E+ Sbjct: 930 DLEEELQEEQKLRNTLEKLKKKYEEELEEMKRVNDGQSDTISRLEK-------IKDELQK 982 Query: 270 EHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIE 329 E +L + + L + + + +E ++K L L +K + Sbjct: 983 EVEELTESFSEESKDKGVLEKTRVRLQSELDDLTVRLDSETKDKSEL-------LRQKKK 1035 Query: 330 LLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPW-SQ 388 L E L E KLA K ++ S + R+ K K SQ Sbjct: 1036 LEEELKQVQEALAAETAAKLAQEAANKKLQGEYTELNEKFNSEVTARSNVEKSKKTLESQ 1095 Query: 389 LSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDK-EYVISEKDTXXXXXXXXXXGKDT 447 L + D +KK N++ + K + + ++ +++ D+ E EK + + Sbjct: 1096 LVAVNNELDEEKK-NRDALEKKKKALDAMLEEMKDQLESTGGEKKSLYDLKVKQESDMEA 1154 Query: 448 LIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLK- 506 L Q+ E Q + L + + E E+A++Q +L+ E ++ NV+ +K++ Sbjct: 1155 LRNQIS-ELQSTI--AKLEKIKSTLE--GEVARLQGELEAE---QLAKSNVEKQKKKVEL 1206 Query: 507 SAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHH 566 E++ QL +E AA + + K+K + +L ++Q +++S++N + V H Sbjct: 1207 DLEDKSAQLAEE-TAAKQALDKLKKKLEQELSEVQ------TQLSEANNKNVNSDSTNKH 1259 Query: 567 LSQKVAELEEEKGNLQLHLVDYDSGRM-IESDVYKKMIEMENLAETRLKAISLLESQKFD 625 L L+ E Q + R+ +ES++ K + E L E + K E +K D Sbjct: 1260 LETSFNNLKLELEAEQKAKQALEKKRLGLESEL--KHVN-EQLEEEK-KQKESNEKRKVD 1315 Query: 626 LVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENL 685 L +E+ L+ D++E+++A S + +E K+ E ++D + K++ A V+ + Sbjct: 1316 LEKEVSELK---DQIEEEVA------SKKAVTEAKN-KKESELDEI---KRQYADVVSSR 1362 Query: 686 KLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQS 745 EQL K L+ E++ N + + +D ++ +K + + E + + E Sbjct: 1363 DKSVEQL----KTLQAKNEELRNTAEE-AEGQLDRAERSKKKAEFDLEEAVKNLEEETAK 1417 Query: 746 KIQTQFGI---DAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQL 802 K++ + + + + +++ ++ S+ +I RL E ++ + R LE ++ Sbjct: 1418 KVKAEKAMKKAETDYRSTKSELDDAKNVSSEQYVQIKRLNEELS---ELRSVLEEADERC 1474 Query: 803 GSYLQEKQKAYSEYTIQEDEL---VNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILL 859 S ++ K+ A S +DE+ N A + +E ++ E+E E+ E K + + Sbjct: 1475 NSAIKAKKTAESALESLKDEIDAANNAKAKAERKSKELEVRVAELE-ESLE-DKSGTVNV 1532 Query: 860 EENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIV 919 E + + D++ + E ++D + + K Q DLE+ ++ E T I Sbjct: 1533 EFIRKKDAEIDDLRARLDRETESRIKSDEDKKNTRK---QFADLEAKVEEAQREVVT-ID 1588 Query: 920 QKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNI--ENLNMN 977 + KK++E I+ +TQ+++ + ++ EK +K +E +E + E + Sbjct: 1589 RLKKKLESDIIDLSTQLDTETK-SRIKIEKSKKKLEQTLAERRAAEEGSSKAADEEIRKQ 1647 Query: 978 V-EELNKMNLEL---------IDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIA 1027 V +E++++ +L +K ++ + + EQ +EI + L+K K + Sbjct: 1648 VWQEVDELRAQLDSERAALNASEKKIKSLVAEVDEVKEQLEDEILAKDKLVKAKRALEVE 1707 Query: 1028 LNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEE----EMQRVSKQLLDSKQHNEELQI 1083 L + + + S S+ E + TT++E++++ E+++ +K K+ +++ Sbjct: 1708 LEEVRDQLEEEEDSR-SELEDSKRRLTTEVEDIKKKYDAEVEQNTKLDEAKKKLTDDVDT 1766 Query: 1084 LVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLK 1143 L ++ +D+ K+L E++ + + E + E + D K Sbjct: 1767 LKKQLEDEKKKLNESERAKKRLESENEDFLAKLDAEVKNRSRAEKDRKKYEKDLKDTKYK 1826 Query: 1144 VQEEEEFIQERSV----LQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQI--- 1196 + +E + + L++Q +L ++L++ K Q + L G + QI Sbjct: 1827 LNDEAATKTQTEIGAAKLEDQIDELRSKLEQEQAKATQADKSKKTLEGEIDNLRAQIEDE 1886 Query: 1197 NQLKSKLEQ----LNTENDNLLSTVAELRSSISSAVDQRGFEIAELW-KQHLAQREADFQ 1251 ++K +LE+ L E + L TV E S S A + EL + Q+E D + Sbjct: 1887 GKIKMRLEKEKRALEGELEELRETVEEAEDSKSEAEQSKRLVELELEDARRNLQKEIDAK 1946 Query: 1252 KTEHELR--VQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNL 1309 + + + +Q E+K +S+ + + + K + E + +L ++ D E+ +N Sbjct: 1947 EIAEDAKSNLQREIVEAKGRLEEESIARTNSDRSRKRLEAE-IDALTAQV-DAEQKAKNQ 2004 Query: 1310 QEK 1312 Q K Sbjct: 2005 QIK 2007 Score = 93.9 bits (223), Expect = 3e-17 Identities = 187/932 (20%), Positives = 384/932 (41%), Gaps = 79/932 (8%) Query: 674 SKKELALVIEN-LKLDKEQLYGTIKDLENDKEDIMNKL--QNYIQENMDLTDKLEKMSAE 730 + K+L +E+ + LD+ + G ++ + ++ N++ ++++ L + + + + Sbjct: 659 NNKQLPAKLEDKVVLDQLRCNGVLEGIRITRKGFPNRIIYADFVKRYYLLAPNVPRDAED 718 Query: 731 KISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAV--M 788 A + H Q +FGI KI R + IE + S I + ++ + Sbjct: 719 SQKATDAVLKHLNIDPEQYRFGI-TKIFFRAGQLARIEEAREQRISEIIKAIQAATRGWI 777 Query: 789 EDRRYSLERKADQLGSYLQEKQKAYSEYTIQED-ELVNRLAVLMDHDRVVEKQLLEIEHE 847 + Y R+ +Q+ +AY ++ +L ++ L+ R EK++ E E E Sbjct: 778 ARKVYKQAREHTVAARIIQQNLRAYIDFKSWPWWKLFSKARPLLKR-RNFEKEIKEKERE 836 Query: 848 NKELQKKNQILLEENQNLQISLSDMQQHYNALVE--KANRTDLAESESTK--YQTQLRDL 903 EL+ + L+ SL D + + L KA + L +K + Q R+L Sbjct: 837 ILELKSNLTDSTTQKDKLEKSLKDTESNVLDLQRQLKAEKETLKAMYDSKDALEAQKREL 896 Query: 904 ESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQ 963 E ++ + E + +KK +E+L+ + +E +RD L E+ ++ + LE Sbjct: 897 EIRVEDMESE----LDEKKLALENLQNQ-KRSVEEKVRD---LEEELQEEQKLRNTLEKL 948 Query: 964 LQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDE 1023 ++Y+ +E + V + + ++K + Q + + TE + E L K + Sbjct: 949 KKKYEEELEEMK-RVNDGQSDTISRLEKIKDELQKEVEELTESFSEESKDKGVLEKTR-- 1005 Query: 1024 EIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQI 1083 + L ++++ V S D +S+L + KLE +++Q +K E Sbjct: 1006 --VRLQSELDDLTVRLDSETKD-KSELLRQKKKLEEELKQVQEALAAETAAKLAQEAANK 1062 Query: 1084 LVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLK 1143 ++ + ++ E +++T N+ K++ T+E NN + Sbjct: 1063 KLQGEYTELNEKFNSEVTARSNVEKSK-----KTLESQLVAVNN---------------E 1102 Query: 1144 VQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKL 1203 + EE++ R L+++ L+ L+E QLE+ E + +Q +S + Sbjct: 1103 LDEEKK---NRDALEKKKKALDAMLEEMKD---QLESTGGEKKSLYDLKVKQ----ESDM 1152 Query: 1204 EQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLS- 1262 E L + L ST+A+L S+ + EL + LA+ + QK + EL ++ Sbjct: 1153 EALRNQISELQSTIAKLEKIKSTLEGEVARLQGELEAEQLAKSNVEKQKKKVELDLEDKS 1212 Query: 1263 ---AFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQ 1319 A E+ +Q LD ++ ++E +++ T Q++ NK + + ++L+ + N Sbjct: 1213 AQLAEETAAKQALDKLKKKLEQELSEVQT--QLSEANNKNVNSDSTNKHLETSF----NN 1266 Query: 1320 IEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKK 1379 +++ + K A L E + K+ E+ +++ +E ++LK Sbjct: 1267 LKLELEAEQKAKQALEKKRLGLESELKHVNEQLEEEKKQ-KESNEKRKVDLEKEVSELKD 1325 Query: 1380 SSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQ 1439 N E+++ E+ Q S K+ E TL +N+E N + Sbjct: 1326 QIEEEVASKKAVTEAKNKKESELDEIKRQYADVVSS-RDKSVEQLKTLQAKNEELRNTAE 1384 Query: 1440 ----QLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQK-ESEIERVK--LIEELN 1492 QL E+ + ++ E + L + + + M+K E++ K L + N Sbjct: 1385 EAEGQLDRAERSKKKAEFDLEEAVKNLEEETAKKVKAEKAMKKAETDYRSTKSELDDAKN 1444 Query: 1493 VKITESVS---LNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRA 1549 V + V LN++++EL LEE + N A + E + +L DEI + N +A Sbjct: 1445 VSSEQYVQIKRLNEELSELRSVLEEADERCNSAIKAKKTAESALESLKDEI-DAANNAKA 1503 Query: 1550 SSSKIQKHVSFASDTKQGRDEQLDNTMNKELL 1581 + + K + + E T+N E + Sbjct: 1504 KAERKSKELEVRVAELEESLEDKSGTVNVEFI 1535 >UniRef50_Q0IVY3 Cluster: Os10g0547000 protein; n=4; Oryza sativa|Rep: Os10g0547000 protein - Oryza sativa subsp. japonica (Rice) Length = 1537 Score = 122 bits (295), Expect = 6e-26 Identities = 221/1123 (19%), Positives = 481/1123 (42%), Gaps = 75/1123 (6%) Query: 516 NDEIDAANKNMIKVKSNHKLK--LKQMQKTIDNF-SKVSDSNKEIVRLTEELHHLSQKVA 572 N + A++ + + +H K L+ ++TID + ++ +L + L L + Sbjct: 284 NAQPSASDLSQLSSGVSHASKDVLENAEETIDELRGEAKMWQRKTRKLKQGLETLKKVST 343 Query: 573 ELEEEKGNLQLHLVDYDSGRMIES--DVYKKMIEMENLAETRLKA-ISLLESQKFDLVQE 629 + +++ L + R ++ + KK ++ ++ L+ +S+ S++ L QE Sbjct: 344 DKSKQRSEQDLEKMWQRKTRKLKQGLETLKKECADKSKQQSELELELSISISERDSLRQE 403 Query: 630 LHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDK 689 + L++ +EV + IS+ E++ +E+ + L S LA + + Sbjct: 404 IEELKRSLEEVTARQT-ISRSPRSGDAIELQK-EVEDDVQFLKESNASLATQLNKAQEAN 461 Query: 690 EQLYGTIKDLENDKEDIMNKLQNYIQENMDLTD---KLEKMSAEKISELLAKINHEEQSK 746 +L +++LE E ++ N + DL D + ++ E K++ +E Sbjct: 462 IELVSILQELEETIEVQRAEISN-LSHTSDLIDHEVSPNNLLIQEDVEWARKVSLKEDEI 520 Query: 747 IQTQFGIDAKIQERD--------LYIENIESELSKYKSRICRLEESIAVMEDRRYSLERK 798 + + ID + + +Y+E +E E K +I LE+ + + D L K Sbjct: 521 LMLREKIDRMLHVENPNGEGSGAIYLE-LEKENDFLKVKIQELEKDCSELTDENLELIYK 579 Query: 799 ADQLGSYLQEKQKAY--SEYTIQEDELVNRLAVLMDHDRV----VEKQLLEIEHENKELQ 852 ++ + + + SE E +L +RL + + +E +L+ E+ EL+ Sbjct: 580 LKEVSEVAKGEDPSVPNSEEVSSEGDLSDRLTSKVKYLETKCADLELKLISFRSESSELE 639 Query: 853 KKNQILLEENQNLQISLSDMQQH---YNALVEKANRTDLAESESTKYQTQLRDLESNLKR 909 +K Q EE ++ + LSD++ ++AL + TD A +S K +++ D N Sbjct: 640 EKLQKSQEELKDRILELSDLRDKLSGFHALEMEEGDTDSA--KSYKLKSEKLDENDNKTE 697 Query: 910 ITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKN 969 + T+++ K++EIE L+ ++ES I +++NEK +E + LE L+E Sbjct: 698 LDALRSTVLL-KEQEIESLQ-HSKKEMESFI--SEIMNEK--NKLEEL--LEESLKECSI 749 Query: 970 NIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALN 1029 L+ EEL + ID HV TE ++N L + + + E + L+ Sbjct: 750 TAACLDEMREELLLLT-SSIDSHVSTNNVLETKITELESCKVN-LELHISKLEHENVELS 807 Query: 1030 QKINNAQVSYMSMVSDYESKLAQF---TTKLENMEEEMQRVSKQLLDSKQHNEELQILVR 1086 + I+ + + ++ E + Q + + N+++E+++V Q ++ K +E + L+ Sbjct: 808 EFISGLESQLTYLANEKELSMLQMDESRSLITNLKDELEQVEAQKVELKLQMDESRSLIT 867 Query: 1087 EQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQE 1146 D++++++ K+ ++ + ++ +I + E +A V+ +VQE Sbjct: 868 NLKDELEQVEAQKVELKLQMDESRSLITNLKDELEQVEAQKVELKENQLESHRRLSEVQE 927 Query: 1147 EEEFIQERSV-LQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQ 1205 + E ++ + LQ + E + T L+ E+ G+ ++++ Q K K Sbjct: 928 DSEALRRSNAKLQATVDHVVEECKSLQTLTADLKKQKLEVHGYASHLEQELEQSKRKTMD 987 Query: 1206 LNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREAD------FQKTEHELRV 1259 ++L + ++ L+ IS E+ ++++H E K E E V Sbjct: 988 FCKTLESLEAKLSSLQEDISLKEQSLLSELENIFQEHKEHEERIDRVHLLLNKIEKEKTV 1047 Query: 1260 QLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQ 1319 +LS E + L + S+ +E + + V +++ ++ + NL++ ++ + Sbjct: 1048 ELSNLEREVISLTAQLSSTEEERESSTLDTIHVDNMRRSIEAARSNEDNLRKTLCEL--E 1105 Query: 1320 IEILRSEIEDEKVAFXXXXXXXXXXXXXXXXD----LRT---ENQSYKQMQEQSILNINE 1372 ++ S+ E +++ D L++ E + K E I +++E Sbjct: 1106 LKSKSSDYEKQQIIEEISVLKIQVHKIAGLQDEVLTLQSSLDEAKFEKGKLEGLIQSLSE 1165 Query: 1373 ENAQLKKSSXXXXXXXXXXXXRVNDA-EAKVLELTHQLE---LKDSEIYQKTHEYTITLT 1428 E +LK +N A E K +E++ Q + L D ++T + + Sbjct: 1166 ECEELKAQKGMLTDKVSCMQDTLNAANEGKQIEISAQTKLVMLGDEPPVKETSD--VLEA 1223 Query: 1429 QRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLI 1488 + E +R EY+++I L ++E+E R ++ E +T Q + E ++ Sbjct: 1224 ELKSELSIIRGANSEYQQKIYSL--QEENEDLTRRNQLMEKELDLKTSQNKDENTNKQVS 1281 Query: 1489 EELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVR 1548 + V + +S SL++ E N LE + +E L+ Q+ L D+++ +Q+ + Sbjct: 1282 LQDEVLMLQS-SLDEAKFE-NGKLEGLLQSLSEECEELKAQK---GMLTDKVSCMQDTLN 1336 Query: 1549 ASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDL 1591 A++ Q +S + DE ++L+A ++EL + Sbjct: 1337 AANEGKQIEISAQTKLVMLGDEP-PVKETSDVLEAELKSELSI 1378 Score = 109 bits (261), Expect = 8e-22 Identities = 261/1231 (21%), Positives = 502/1231 (40%), Gaps = 119/1231 (9%) Query: 373 KSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKD 432 K G T K+ + S+ SE QD +K + + KL+ +++L K+ DK SE + Sbjct: 332 KQGLETLKKVSTDKSKQRSE---QDLEKMWQR-KTRKLKQGLETLKKECADKSKQQSELE 387 Query: 433 TXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDE 492 +D+L +++ E ++ +E + + + + ++Q++++ ++ Sbjct: 388 LELSISISE---RDSLRQEIE-ELKRSLEEVTARQTISRSPRSGDAIELQKEVEDDVQF- 442 Query: 493 IKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSD 552 +K+ N L +L A+E +L + + I+V+ L ID+ +VS Sbjct: 443 LKESNAS-LATQLNKAQEANIELVSILQELEET-IEVQRAEISNLSHTSDLIDH--EVSP 498 Query: 553 SNKEIVRLTEELHHLSQKVAELE--EEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAE 610 +N I E +S K E+ EK + LH V+ +G +Y +E+E + Sbjct: 499 NNLLIQEDVEWARKVSLKEDEILMLREKIDRMLH-VENPNGEG-SGAIY---LELEKEND 553 Query: 611 TRLKAISLLESQKFDLVQELHILQQKYDEVED--KLADISQLQSDQVCSEIKSVHLEEQI 668 I LE +L E L K EV + K D S S++V SE + Sbjct: 554 FLKVKIQELEKDCSELTDENLELIYKLKEVSEVAKGEDPSVPNSEEVSSE------GDLS 607 Query: 669 DALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMS 728 D L++ K L +L+L +LE + +L++ I E DL DKL Sbjct: 608 DRLTSKVKYLETKCADLELKLISFRSESSELEEKLQKSQEELKDRILELSDLRDKLSGFH 667 Query: 729 AEKISELLAKINHEEQSKIQTQFGIDAKIQERD--LYIENIESELSKYKSRICRLEESIA 786 A ++ E + + K++++ K+ E D ++ + S + + I L+ S Sbjct: 668 ALEMEE--GDTDSAKSYKLKSE-----KLDENDNKTELDALRSTVLLKEQEIESLQHSKK 720 Query: 787 VMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVL-------MDHDRVVEK 839 ME + + ++L L+E K S DE+ L +L + + V+E Sbjct: 721 EMESFISEIMNEKNKLEELLEESLKECSITAACLDEMREELLLLTSSIDSHVSTNNVLET 780 Query: 840 QLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQ 899 ++ E+E L+ L EN L +S ++ L + + L ES T Sbjct: 781 KITELESCKVNLELHISKLEHENVELSEFISGLESQLTYLANEKELSMLQMDESRSLITN 840 Query: 900 LRD-LES------NLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEK 952 L+D LE LK E ++LI K E+E +E + +++ + + + L + Sbjct: 841 LKDELEQVEAQKVELKLQMDESRSLITNLKDELEQVEAQ-KVELKLQMDESRSLITNLKD 899 Query: 953 NIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEIN 1012 +E Q+EAQ E K N + + E+ + + L + + Q T D+ + + Sbjct: 900 ELE---QVEAQKVELKENQLESHRRLSEVQEDSEALRRSNAKLQATV--DHVVEECKSLQ 954 Query: 1013 KLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLL 1072 L A LK++ E+ + D+ L KL +++E++ + LL Sbjct: 955 TLTADLKKQKLEVHGYASHLEQELEQSKRKTMDFCKTLESLEAKLSSLQEDISLKEQSLL 1014 Query: 1073 --------DSKQHNEE-------LQILVREQDDQIKELKETKLTFEMNIPKTEGMIISST 1117 + K+H E L + +E+ ++ L+ ++ + TE SST Sbjct: 1015 SELENIFQEHKEHEERIDRVHLLLNKIEKEKTVELSNLEREVISLTAQLSSTEEERESST 1074 Query: 1118 IEPMSDD---------ANNVDXXXXXXXXXXXXLKVQ--EEEEFIQERSVLQEQSAKLNT 1166 ++ + D +N D K E+++ I+E SVL+ Q K+ Sbjct: 1075 LDTIHVDNMRRSIEAARSNEDNLRKTLCELELKSKSSDYEKQQIIEEISVLKIQVHKI-A 1133 Query: 1167 ELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISS 1226 LQ+ +++ L++ E + I L + E+L + L V+ ++ ++++ Sbjct: 1134 GLQD---EVLTLQSSLDEAKFEKGKLEGLIQSLSEECEELKAQKGMLTDKVSCMQDTLNA 1190 Query: 1227 AVDQRGFEIAELWKQHLAQREADFQKT----EHELRVQLSAFE---SKYEQLLDSVQSST 1279 A + + EI+ K + E ++T E EL+ +LS S+Y+Q + S+Q Sbjct: 1191 ANEGKQIEISAQTKLVMLGDEPPVKETSDVLEAELKSELSIIRGANSEYQQKIYSLQEEN 1250 Query: 1280 QEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXX 1339 ++ T + ME+ L+ Q+K+E+ K + +++ +L+S +++ K Sbjct: 1251 EDLTRRNQLMEKELDLKTS-QNKDEN----TNKQVSLQDEVLMLQSSLDEAKFE-NGKLE 1304 Query: 1340 XXXXXXXXXXXDLRTEN--QSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVND 1397 +L+ + + K Q LN E Q++ S+ Sbjct: 1305 GLLQSLSEECEELKAQKGMLTDKVSCMQDTLNAANEGKQIEISAQTKLVMLGDEPPVKET 1364 Query: 1398 AEAKVLELTHQLEL---KDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYE 1454 ++ EL +L + +SE QK H +L + N++ R QL+ EK ++ T + Sbjct: 1365 SDVLEAELKSELSIIRGANSEYQQKIH----SLQKENEDLTR-RNQLM--EKELDLKTSQ 1417 Query: 1455 KESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQV-AELNKALE 1513 + E K +AN E I+ L ++ E++ NK +L + Sbjct: 1418 NKDENT---NKQGNDANENGDSPVNEVPELQSKIQLLETRLAEALEENKLYRGQLKSPMP 1474 Query: 1514 EEVAKTNEMQTALENQEIEIVTLNDEITNLQ 1544 E + + + EN + +I L E+ ++Q Sbjct: 1475 EGKSASKD---GKENDDDKISQLESELKDMQ 1502 Score = 92.3 bits (219), Expect = 1e-16 Identities = 179/862 (20%), Positives = 373/862 (43%), Gaps = 54/862 (6%) Query: 504 KLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNF-SKVSDSNKEIVRLTE 562 KLKS + E+DA ++ +K L+ +K +++F S++ + ++ L E Sbjct: 683 KLKSEKLDENDNKTELDALRSTVL-LKEQEIESLQHSKKEMESFISEIMNEKNKLEELLE 741 Query: 563 E-LHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLES 621 E L S A L+E + L L DS + + K+ E+E+ IS LE Sbjct: 742 ESLKECSITAACLDEMREELLLLTSSIDSHVSTNNVLETKITELESCKVNLELHISKLEH 801 Query: 622 QKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALV 681 + +L + + L+ + + ++ ++S LQ D+ S I +L+++++ + A K EL L Sbjct: 802 ENVELSEFISGLESQLTYLANE-KELSMLQMDESRSLI--TNLKDELEQVEAQKVELKLQ 858 Query: 682 IENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINH 741 ++ + L ++ +E K ++ ++ +L D+LE++ A+K+ EL K N Sbjct: 859 MDESRSLITNLKDELEQVEAQKVELKLQMDESRSLITNLKDELEQVEAQKV-EL--KENQ 915 Query: 742 EEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQ 801 E + ++ D++ R +++ + L+ A ++ ++ + A Sbjct: 916 LESHRRLSEVQEDSEALRRSN--AKLQATVDHVVEECKSLQTLTADLKKQKLEVHGYASH 973 Query: 802 LGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLL-EIEH---ENKELQKK--- 854 L L++ ++ ++ + L +L+ L + + E+ LL E+E+ E+KE +++ Sbjct: 974 LEQELEQSKRKTMDFCKTLESLEAKLSSLQEDISLKEQSLLSELENIFQEHKEHEERIDR 1033 Query: 855 -NQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESEST----KYQTQLRDLESNLKR 909 + +L + + + LS++++ +L + + T+ ST R +E+ Sbjct: 1034 VHLLLNKIEKEKTVELSNLEREVISLTAQLSSTEEERESSTLDTIHVDNMRRSIEAARSN 1093 Query: 910 ITHEHQTLI-VQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYK 968 + +TL ++ K + D E + QI I K+ K + V L++ L E K Sbjct: 1094 EDNLRKTLCELELKSKSSDYEKQ---QIIEEISVLKIQVHKIAGLQDEVLTLQSSLDEAK 1150 Query: 969 NN-------IENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQK 1021 I++L+ EEL L DK Q T + + I EI+ L+ Sbjct: 1151 FEKGKLEGLIQSLSEECEELKAQKGMLTDKVSCMQDTLNAANEGKQI-EISAQTKLVMLG 1209 Query: 1022 DEEIIALNQKINNAQV-SYMSMV----SDYESKLAQFTTKLENMEEEMQRVSKQL-LDSK 1075 DE + + A++ S +S++ S+Y+ K+ + E++ Q + K+L L + Sbjct: 1210 DEPPVKETSDVLEAELKSELSIIRGANSEYQQKIYSLQEENEDLTRRNQLMEKELDLKTS 1269 Query: 1076 QHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXX 1135 Q+ +E D++ L+ + + K EG++ S E + Sbjct: 1270 QNKDENTNKQVSLQDEVLMLQSSLDEAKFENGKLEGLL-QSLSEECEELKAQKGMLTDKV 1328 Query: 1136 XXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELT---GHDVVN 1192 L E + I+ + Q + L E T + L +EL+ G + Sbjct: 1329 SCMQDTLNAANEGKQIEISA--QTKLVMLGDEPPVKETSDVLEAELKSELSIIRGANSEY 1386 Query: 1193 QEQINQLKSKLEQLNTENDNLLSTVAELRSSISSA--VDQRGFEIAELWKQ---HLAQRE 1247 Q++I+ L+ + E L T + L+ +L++S + +++G + E + + + Sbjct: 1387 QQKIHSLQKENEDL-TRRNQLMEKELDLKTSQNKDENTNKQGNDANENGDSPVNEVPELQ 1445 Query: 1248 ADFQKTEHELRVQLSAFESKYEQLLDSV-QSSTQEETNKIVTMEQVTSLQNKLQDKEEHL 1306 + Q E L L + QL + + + + K ++++ L+++L+D +E L Sbjct: 1446 SKIQLLETRLAEALEENKLYRGQLKSPMPEGKSASKDGKENDDDKISQLESELKDMQERL 1505 Query: 1307 RNLQEKYADVINQIEILRSEIE 1328 N+ +YA+V Q E L E++ Sbjct: 1506 LNVSLQYAEVEAQREELVMELK 1527 Score = 84.6 bits (200), Expect = 2e-14 Identities = 229/1171 (19%), Positives = 480/1171 (40%), Gaps = 92/1171 (7%) Query: 147 LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXX 206 L +K S L++++ I + L+++I E + +E T Sbjct: 372 LKKECADKSKQQSELELELSISISERDSLRQEIEELKRSLEEVTARQTISRSPRSGDAIE 431 Query: 207 XXXXXEDTKQQMTKMQENFI-----AMEA--EWKDEKQRLLKDIESKDVRISSLEEANKL 259 ED Q + + + A EA E Q L + IE + IS+L + L Sbjct: 432 LQKEVEDDVQFLKESNASLATQLNKAQEANIELVSILQELEETIEVQRAEISNLSHTSDL 491 Query: 260 LEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCE-EKTEIEEKGS--L 316 ++ E+S + + +++E + ++ I+ E E G+ L Sbjct: 492 ID---HEVSPNNLLIQEDVEWARKVSLKEDEIL--MLREKIDRMLHVENPNGEGSGAIYL 546 Query: 317 EIANMTELTK-KIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSG 375 E+ + K KI+ LE ++ N EL KL + +K PS S +S + Sbjct: 547 ELEKENDFLKVKIQELEKDCSELTDENLELIYKLKEVSEVAKG-EDPSVPNSEEVSSEG- 604 Query: 376 RNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISE-KDTX 434 + + ++ S L ++ + + ++E ++LE +Q ++L D+ +S+ +D Sbjct: 605 -DLSDRLTSKVKYLETKCADLELKLISFRSESSELEEKLQKSQEELKDRILELSDLRDKL 663 Query: 435 XXXXXXXXXGKDTLIAQ-LQLEHQQHMEGPSLIHVGTNTEDV----NEIAKVQEQLKQEL 489 DT A+ +L+ ++ E + + V EI +Q K+E+ Sbjct: 664 SGFHALEMEEGDTDSAKSYKLKSEKLDENDNKTELDALRSTVLLKEQEIESLQHS-KKEM 722 Query: 490 NDEIKDV-NVKDLIEKL--KSAEE-QIT-----QLNDEIDAANKNMIK-VKSNHKL--KL 537 I ++ N K+ +E+L +S +E IT ++ +E+ ++ V +N+ L K+ Sbjct: 723 ESFISEIMNEKNKLEELLEESLKECSITAACLDEMREELLLLTSSIDSHVSTNNVLETKI 782 Query: 538 KQMQKTIDNFS-KVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDY-------- 588 +++ N +S E V L+E + L ++ L EK L + + Sbjct: 783 TELESCKVNLELHISKLEHENVELSEFISGLESQLTYLANEKELSMLQMDESRSLITNLK 842 Query: 589 DSGRMIESDVYKKMIEMENLAE--TRLK-AISLLESQKFDLVQELH----ILQQKYDEVE 641 D +E+ + ++M+ T LK + +E+QK +L ++ ++ DE+E Sbjct: 843 DELEQVEAQKVELKLQMDESRSLITNLKDELEQVEAQKVELKLQMDESRSLITNLKDELE 902 Query: 642 DKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLEN 701 A +L+ +Q+ S + ++E +AL S +L ++++ + + L DL+ Sbjct: 903 QVEAQKVELKENQLESHRRLSEVQEDSEALRRSNAKLQATVDHVVEECKSLQTLTADLKK 962 Query: 702 DKEDIMNKLQNYIQE-------NMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGID 754 K ++ + QE MD LE + A K+S L I+ +EQS + I Sbjct: 963 QKLEVHGYASHLEQELEQSKRKTMDFCKTLESLEA-KLSSLQEDISLKEQSLLSELENIF 1021 Query: 755 AKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYS 814 + +E + I+ + L+K + E+++ + R + A QL S +E++ + Sbjct: 1022 QEHKEHEERIDRVHLLLNKIEK-----EKTVELSNLEREVISLTA-QLSSTEEERESSTL 1075 Query: 815 EYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQ 874 + TI D + + ++ + K L E+E ++K + Q ++EE L+I + + Sbjct: 1076 D-TIHVDNMRRSIEAARSNEDNLRKTLCELELKSKSSDYEKQQIIEEISVLKIQVHKIAG 1134 Query: 875 HYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFN- 933 + ++ + D A+ E K + ++ L + + + + ++ K ++D N Sbjct: 1135 LQDEVLTLQSSLDEAKFEKGKLEGLIQSLSEECEELKAQ-KGMLTDKVSCMQDTLNAANE 1193 Query: 934 -TQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQ-----------EYKNNIENLNMNVEEL 981 QIE + + K V+ E LEA+L+ EY+ I +L E+L Sbjct: 1194 GKQIEISAQTKLVMLGDEPPVKETSDVLEAELKSELSIIRGANSEYQQKIYSLQEENEDL 1253 Query: 982 NKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMS 1041 + N +L++K + + +Q+ D + +L+ +E N K+ S Sbjct: 1254 TRRN-QLMEKELDLKTSQNKDENTNKQVSLQDEVLMLQSSLDEAKFENGKLEGLLQSLSE 1312 Query: 1042 MVSDYESKLAQFTTKLENMEEEMQRVS--KQLLDSKQHNEELQILVREQD-DQIKELKET 1098 + +++ T K+ M++ + + KQ+ S Q +L +L E + ++ E Sbjct: 1313 ECEELKAQKGMLTDKVSCMQDTLNAANEGKQIEISAQ--TKLVMLGDEPPVKETSDVLEA 1370 Query: 1099 KLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQER-SVL 1157 +L E++I + I + + ++ Q ++E ++ + Sbjct: 1371 ELKSELSIIRGANSEYQQKIHSLQKENEDLTRRNQLMEKELDLKTSQNKDENTNKQGNDA 1430 Query: 1158 QEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTE-NDNLLST 1216 E E+ E +KI LET E + + + Q+ + + + + +N Sbjct: 1431 NENGDSPVNEVPELQSKIQLLETRLAEALEENKLYRGQLKSPMPEGKSASKDGKENDDDK 1490 Query: 1217 VAELRSSISSAVDQRGFEIAELWKQHLAQRE 1247 +++L S + + +R ++ + + AQRE Sbjct: 1491 ISQLESELKD-MQERLLNVSLQYAEVEAQRE 1520 >UniRef50_A0DSK6 Cluster: Chromosome undetermined scaffold_61, whole genome shotgun sequence; n=1; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_61, whole genome shotgun sequence - Paramecium tetraurelia Length = 1266 Score = 122 bits (295), Expect = 6e-26 Identities = 218/976 (22%), Positives = 419/976 (42%), Gaps = 103/976 (10%) Query: 403 NKNEIA-KLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHME 461 NK E+ L+ LN+ + Y+ +++ KD I L + + Sbjct: 242 NKEELKLHLQQQTSKLNEQINKNNYIEQQRNQEIQNLQFQVQVKDKQIQNLLSQIGEQRN 301 Query: 462 GPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDA 521 +L + E + ++ + QL QE++ + + + L ++ K ++ +TQL E + Sbjct: 302 KTNL----QDQERLQQLENLNNQLVQEIS--VLEGELAKLKQQAKDFQK-VTQLEKENEN 354 Query: 522 ANKNMIKVK-SNH--KLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEK 578 + K NH K +LK +Q+ I+ + + ++L +E+ + ++ ++EL+EE Sbjct: 355 LQMIIQDQKVQNHDTKQQLKLLQEEINQLKGQNQNKSNTIQLEQEIKYYARLLSELQEEN 414 Query: 579 GNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYD 638 G LQ L+D++ I ++ E L + + + L+E Q ++Q L+Q+ + Sbjct: 415 GKLQNQLLDFEE---INEELLLLRRNNEELQQQQTEDSKLVEDQSLKIIQ----LEQELN 467 Query: 639 EVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKD 698 + Q Q + + E L +QI+ L+ KE E L L + Sbjct: 468 HLR------QQNQQESIIKE-----LNKQIEQLNQINKERE--AEILYQQDLLLKQNVNS 514 Query: 699 LENDKEDIMNKLQN--YIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAK 756 E DK K +N Y +N LT++ K S +I E K + E K+QT + Sbjct: 515 KEFDKLITEQKAENKEYQIQNNQLTNQELKKSQLEI-ESYNKKHEENLQKMQTLEKDKQQ 573 Query: 757 IQER-DLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSE 815 IQ D +I+ I+ + ++ S +LE A + +R L+ + +L ++Q S Sbjct: 574 IQNNFDHHIKEIQKKDAEKLSNFTQLENENAKLYQQRNKLQERIGELEEAANQQQIELSN 633 Query: 816 YTIQEDELVNRLAV----LMDHDRVVEK-QLLEIEHEN---------KELQKKNQILLEE 861 +EL+N+L L+D++ V+K L E +N K+L+ +NQ L + Sbjct: 634 LKKDNEELLNQLETQNSHLIDNNEQVQKVNFLNQEQQNIINEKELFIKQLESQNQELELK 693 Query: 862 NQNLQISLSDMQQHYNAL--VEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIV 919 + L I + + Q+ ++ N +L E + + ++LE+ L + + I Sbjct: 694 VEKLSIEIQEQQEQQQNFENQQEGNDQELLLQEIDLLKQKNQELENQLNQQIDDDAEEID 753 Query: 920 QKKKEIEDLEIEFN------TQIESAIRDKKVLNEKYEKNIEYVTQL----EAQLQEYKN 969 + +KE+ + +N ++++ D + E+ ++ IE + Q+ + Q E K Sbjct: 754 KLEKELYHQKQNYNELKINLEELQTGKEDSQKRAEEKDEEIERLKQIVFEYQEQQDESKK 813 Query: 970 NIENLNMNVEEL------NK---MNLE--LIDKHVQKQQTQSPDYTEQYIN-EINKLNAL 1017 IE+L N +EL N+ +LE +++K Q + Q +IN E KL Sbjct: 814 QIEDLYNNQKELAIELSENQKIIQDLESTIVEKEEQIKNLQQQTPQNDFINQETEKLMFQ 873 Query: 1018 LKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQH 1077 +KQ E+I NQ I + + +++ +S+L Q ++ M + Q + +L + Sbjct: 874 VKQMQEQIEDQNQTI----LQLENELNNKDSQLKQKLYEIRQMSLQTQLIEIKL---TRE 926 Query: 1078 NEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDA--NNVDXXXXXX 1135 E+L+ E Q + + L F+ ++E I S IEP + N D Sbjct: 927 IEDLKNKAFEAIQQRVKYENELLKFQQ---ESEKQIELSRIEPNNQQCTYENEDLSHIAL 983 Query: 1136 XXXXXXLKVQEE--EEFIQERSVLQEQSAKLNTELQECYTKIIQLETL-NTELTGHDVVN 1192 QEE + F + + ++ + + ELQE IIQ+E EL D Sbjct: 984 GKAPEAEDNQEEYSQSFEEYQEEIEVKDQEKQEELQEPQINIIQIEEAPQIEL---DKEE 1040 Query: 1193 QEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQK 1252 E++ +L + +Q EN + EL+ I+ + ++ EL ++ Q + QK Sbjct: 1041 NEEVFELCNAQKQ--EENSD-----QELKEPIAEIIQDDEYQQIELDEKPKDQFGIN-QK 1092 Query: 1253 TEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEK 1312 E + ++L E K Q++ Q + E+V L N D+E+ L++ Sbjct: 1093 YETQNLLELEEPEIKIVQMIQQPQIELDSQKK---NQEEVFELGN-AADEEDDEEELKQV 1148 Query: 1313 YADVINQIEILRSEIE 1328 +++ ++ E++ Sbjct: 1149 VCEIVQNPPNIQIELD 1164 Score = 116 bits (279), Expect = 5e-24 Identities = 246/1180 (20%), Positives = 504/1180 (42%), Gaps = 126/1180 (10%) Query: 414 IQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTE 473 + L K + D ++ I +D+ + + I Q LE + I E Sbjct: 74 VSYLKKKIEDLQFRIDSQDSKLKAREKEIVYQQSQIKQFVLEINEIQ-----IIEDNYKE 128 Query: 474 DVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQ---ITQLNDEIDAANKNMIKVK 530 +++ + K Q K++ +K+ + + +S +EQ + + I+ + M ++ Sbjct: 129 EISVLNKEISQWKEKYFANLKEYQFRQAQQSRQSQQEQGLMRKKYEEIIEQQQREMESIE 188 Query: 531 SNHKLKLKQMQKTIDNFSKVSDSNKE----IVRLTE---ELHHLSQKVAELEEEKGNLQL 583 + + + + + ++ +K N E I++L + E H L +K+ LE K L+L Sbjct: 189 IRFENERENLYRALELQNKTQSKNNELNELIIQLEDKESETHKLKEKIQVLETNKEELKL 248 Query: 584 HLVDYDS--GRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYD-EV 640 HL S I + Y + + + + + + + + Q +L+ ++ + K + + Sbjct: 249 HLQQQTSKLNEQINKNNYIEQQRNQEIQNLQFQ-VQVKDKQIQNLLSQIGEQRNKTNLQD 307 Query: 641 EDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLE 700 +++L + L ++Q+ EI SV LE ++ L K+ V + L+ + E L I+D + Sbjct: 308 QERLQQLENL-NNQLVQEI-SV-LEGELAKLKQQAKDFQKVTQ-LEKENENLQMIIQDQK 363 Query: 701 ---NDKEDIMNKLQNYIQ----ENMDLTDKLE-KMSAEKISELLAKINHEEQSKIQTQFG 752 +D + + LQ I +N + ++ ++ + + + LL+++ EE K+Q Q Sbjct: 364 VQNHDTKQQLKLLQEEINQLKGQNQNKSNTIQLEQEIKYYARLLSEL-QEENGKLQNQLL 422 Query: 753 IDAKIQERDLYIENIESELSKYKSRICRL--EESIAVME-DRRYSLERKADQLGSYLQEK 809 +I E L + EL + ++ +L ++S+ +++ ++ + R+ +Q S ++E Sbjct: 423 DFEEINEELLLLRRNNEELQQQQTEDSKLVEDQSLKIIQLEQELNHLRQQNQQESIIKEL 482 Query: 810 QKAYSEYT----IQEDELVNRLAVLMD---HDRVVEKQLLEIEHENKELQKKNQILLEEN 862 K + +E E++ + +L+ + + +K + E + ENKE Q +N L N Sbjct: 483 NKQIEQLNQINKEREAEILYQQDLLLKQNVNSKEFDKLITEQKAENKEYQIQNNQL--TN 540 Query: 863 QNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKK 922 Q L+ S +++ YN E+ N + E K Q Q + + ++K I Q +K Sbjct: 541 QELKKSQLEIES-YNKKHEE-NLQKMQTLEKDKQQIQ-NNFDHHIKEI----QKKDAEKL 593 Query: 923 KEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELN 982 LE E N ++ + + L E+ + E Q + +L K + E L + +L Sbjct: 594 SNFTQLENE-NAKL---YQQRNKLQERIGELEEAANQQQIELSNLKKDNEEL---LNQLE 646 Query: 983 KMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSM 1042 N LID + Q Q+ + +Q N IN+ +KQ + + L K+ + Sbjct: 647 TQNSHLIDNNEQVQKVNFLNQEQQ--NIINEKELFIKQLESQNQELELKVEKLSIE---- 700 Query: 1043 VSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQ-DDQIKELKETKLT 1101 + + + + F + E ++E+ LL KQ N+EL+ + +Q DD +E+ KL Sbjct: 701 IQEQQEQQQNFENQQEGNDQELLLQEIDLL--KQKNQELENQLNQQIDDDAEEI--DKLE 756 Query: 1102 FEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQS 1161 E+ K + +E + + K +E E Q QEQ Sbjct: 757 KELYHQKQNYNELKINLEELQTGKEDSQKRAEE--------KDEEIERLKQIVFEYQEQQ 808 Query: 1162 AKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELR 1221 + ++++ Y Q E L EL+ NQ+ I L+S + + + NL + Sbjct: 809 DESKKQIEDLYNN--QKE-LAIELS----ENQKIIQDLESTIVEKEEQIKNLQQQTPQ-N 860 Query: 1222 SSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQE 1281 I+ ++ F++ ++ +Q Q + Q E+EL + S + K L + Q S Q Sbjct: 861 DFINQETEKLMFQVKQMQEQIEDQNQTILQ-LENELNNKDSQLKQK---LYEIRQMSLQT 916 Query: 1282 ETNKIVTMEQVTSLQNK----LQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXX 1337 + +I ++ L+NK +Q + ++ L + + QIE+ R E +++ + Sbjct: 917 QLIEIKLTREIEDLKNKAFEAIQQRVKYENELLKFQQESEKQIELSRIEPNNQQCTYENE 976 Query: 1338 XXXXXXXXXXXXXDLRTE--NQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRV 1395 + E +QS+++ QE+ + E+ +L++ ++ Sbjct: 977 DLSHIALGKAPEAEDNQEEYSQSFEEYQEEIEVKDQEKQEELQEP-------------QI 1023 Query: 1396 NDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEK 1455 N + +E Q+EL D E ++ E Q + + +++ + E I+D Y+ Sbjct: 1024 NIIQ---IEEAPQIEL-DKEENEEVFELCNAQKQEENSDQELKEPIAEI---IQDDEYQ- 1075 Query: 1456 ESELAILRLKMHENANHYETMQ----KESEIERVKLIEELNVKITESVSLNKQVAELNKA 1511 + EL YET +E EI+ V++I++ +++ ++V EL A Sbjct: 1076 QIELDEKPKDQFGINQKYETQNLLELEEPEIKIVQMIQQPQIELDSQKKNQEEVFELGNA 1135 Query: 1512 LEEEVAKTNEMQTALE------NQEIEIVTLNDEITNLQN 1545 +EE + Q E N +IE+ ++ I + QN Sbjct: 1136 ADEEDDEEELKQVVCEIVQNPPNIQIELDQGDNNIPHQQN 1175 Score = 110 bits (265), Expect = 3e-22 Identities = 193/906 (21%), Positives = 394/906 (43%), Gaps = 85/906 (9%) Query: 743 EQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEE--SIAVMEDRRYSLERKAD 800 ++ K+ + + + Q+ I ++++++ +SR ++ S E S E Sbjct: 2 DRKKLLFENNLKSNCQDLMAGIRETKAKVNEIRSRCDSIKRGSSKQPFEVNNKSYEISTK 61 Query: 801 QLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKK-NQI-L 858 GS++ K S + ++L R+ + EK+++ + + K+ + N+I + Sbjct: 62 TSGSFINLKDNDVSYLKKKIEDLQFRIDSQDSKLKAREKEIVYQQSQIKQFVLEINEIQI 121 Query: 859 LEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLI 918 +E+N +IS+ + + + EK +L E + + Q Q R + + +++ +I Sbjct: 122 IEDNYKEEISV--LNKEISQWKEKYF-ANLKEYQFRQAQ-QSRQSQQEQGLMRKKYEEII 177 Query: 919 VQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNV 978 Q+++E+E +EI F + E+ R ++ N+ KN E + +L QL++ ++ L + Sbjct: 178 EQQQREMESIEIRFENERENLYRALELQNKTQSKNNE-LNELIIQLEDKESETHKLKEKI 236 Query: 979 EELNKMNLELIDKHVQKQ------QTQSPDYTEQYIN-EINKLNALLKQKDEEIIALNQK 1031 + L + N E + H+Q+Q Q +Y EQ N EI L ++ KD++I L + Sbjct: 237 QVL-ETNKEELKLHLQQQTSKLNEQINKNNYIEQQRNQEIQNLQFQVQVKDKQIQNLLSQ 295 Query: 1032 I----NNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQ------HNEEL 1081 I N + + E+ Q ++ +E E+ ++ +Q D ++ NE L Sbjct: 296 IGEQRNKTNLQDQERLQQLENLNNQLVQEISVLEGELAKLKQQAKDFQKVTQLEKENENL 355 Query: 1082 QILVREQDDQIKELKETK--LTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXX 1139 Q+++++Q Q + K+ L E+N K + S+TI+ + + Sbjct: 356 QMIIQDQKVQNHDTKQQLKLLQEEINQLKGQNQNKSNTIQ-LEQEIKYYARLLSELQEEN 414 Query: 1140 XXLKVQ----EE--EEFI---QERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDV 1190 L+ Q EE EE + + LQ+Q + + +++ KIIQLE EL Sbjct: 415 GKLQNQLLDFEEINEELLLLRRNNEELQQQQTEDSKLVEDQSLKIIQLEQ---ELNHLRQ 471 Query: 1191 VNQEQ--INQLKSKLEQLNTENDNLLSTVAELRSSI-SSAVDQRGFE--IAELWKQHLAQ 1245 NQ++ I +L ++EQLN N + + + + V+ + F+ I E ++ Sbjct: 472 QNQQESIIKELNKQIEQLNQINKEREAEILYQQDLLLKQNVNSKEFDKLITEQKAENKEY 531 Query: 1246 READFQKTEHELR---VQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQ-VTSLQNKLQD 1301 + + Q T EL+ +++ ++ K+E+ L +Q+ +++ + + +Q K + Sbjct: 532 QIQNNQLTNQELKKSQLEIESYNKKHEENLQKMQTLEKDKQQIQNNFDHHIKEIQKKDAE 591 Query: 1302 KEEHLRNLQEKYADVINQIEILRS---EIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQ- 1357 K + L+ + A + Q L+ E+E+ L T+N Sbjct: 592 KLSNFTQLENENAKLYQQRNKLQERIGELEEAANQQQIELSNLKKDNEELLNQLETQNSH 651 Query: 1358 ---SYKQMQEQSILNINEENA---------QLKKSSXXXXXXXXXXXXRVNDAEAKVLEL 1405 + +Q+Q+ + LN ++N QL+ + + + + + Sbjct: 652 LIDNNEQVQKVNFLNQEQQNIINEKELFIKQLESQNQELELKVEKLSIEIQEQQEQQQNF 711 Query: 1406 THQLELKDSEIYQKTHEYTITLTQRNDEFEN-VRQQLVEYEKRIEDLT---YEKESELAI 1461 +Q E D E+ + + L Q+N E EN + QQ+ + + I+ L Y ++ Sbjct: 712 ENQQEGNDQELLLQEIDL---LKQKNQELENQLNQQIDDDAEEIDKLEKELYHQKQNYNE 768 Query: 1462 LRLKMHENANHYETMQK-----ESEIERVK-LIEELNVKITESVSLNKQVAELNKALEEE 1515 L++ + E E QK + EIER+K ++ E + ES KQ+ +L +E Sbjct: 769 LKINLEELQTGKEDSQKRAEEKDEEIERLKQIVFEYQEQQDES---KKQIEDLYNNQKEL 825 Query: 1516 VAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNT 1575 + +E Q +++ E IV ++I NLQ + Q+ KQ EQ+++ Sbjct: 826 AIELSENQKIIQDLESTIVEKEEQIKNLQQQTPQNDFINQETEKLMFQVKQ-MQEQIED- 883 Query: 1576 MNKELL 1581 N+ +L Sbjct: 884 QNQTIL 889 Score = 50.8 bits (116), Expect = 3e-04 Identities = 139/709 (19%), Positives = 292/709 (41%), Gaps = 68/709 (9%) Query: 220 KMQENFIAMEAEWKDEKQ------RLLKDIESKDVR----ISSLEEANKLLEAARFEISL 269 K +EN M+ KD++Q +K+I+ KD + LE N L R ++ Sbjct: 556 KHEENLQKMQTLEKDKQQIQNNFDHHIKEIQKKDAEKLSNFTQLENENAKLYQQRNKLQE 615 Query: 270 EHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIE 329 +L + Q L Q + E+ + N E I Sbjct: 616 RIGELEEAANQQQIELSNLKKDNEELLNQLETQNSHLIDNNEQVQKVNFLNQ-EQQNIIN 674 Query: 330 LLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTA------SKMK 383 E Q+ N+ELE K+ + E + ++ +++ G + +K Sbjct: 675 EKELFIKQLESQNQELELKVEKLSIE---IQEQQEQQQNFENQQEGNDQELLLQEIDLLK 731 Query: 384 SPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXX 443 +L ++ LNQ D + EI KLE + ++ + + + E T Sbjct: 732 QKNQELENQ-LNQQIDD--DAEEIDKLEKELYHQKQNYNELKINLEELQTGKEDSQKRAE 788 Query: 444 GKDTLIAQLQ---LEHQQHM-EGPSLIHVGTNTE-----DVNEIAKVQEQLKQ---ELND 491 KD I +L+ E+Q+ E I N + +++E K+ + L+ E + Sbjct: 789 EKDEEIERLKQIVFEYQEQQDESKKQIEDLYNNQKELAIELSENQKIIQDLESTIVEKEE 848 Query: 492 EIKDVNVK----DLI-EKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDN 546 +IK++ + D I ++ + Q+ Q+ ++I+ N+ ++++++ K Q+++ + Sbjct: 849 QIKNLQQQTPQNDFINQETEKLMFQVKQMQEQIEDQNQTILQLENELNNKDSQLKQKLYE 908 Query: 547 FSKVSDSNKEI-VRLTEELHHLSQKVAELEEEKGNLQLHLVDY--DSGRMIESDVYKKMI 603 ++S + I ++LT E+ L K E +++ + L+ + +S + IE + Sbjct: 909 IRQMSLQTQLIEIKLTREIEDLKNKAFEAIQQRVKYENELLKFQQESEKQIELSRIEPNN 968 Query: 604 EMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCS-EIKSV 662 + L I+L ++ + + QE + Q ++E ++++ Q + +++ +I + Sbjct: 969 QQCTYENEDLSHIALGKAPEAEDNQEEY--SQSFEEYQEEIEVKDQEKQEELQEPQINII 1026 Query: 663 HLEE--QIDALSASKKELALVIENLKLDK---EQLYGTIKDLENDKEDIMNKLQNYIQEN 717 +EE QI+ +E+ + K ++ ++L I ++ D E +L ++ Sbjct: 1027 QIEEAPQIELDKEENEEVFELCNAQKQEENSDQELKEPIAEIIQDDEYQQIELDEKPKDQ 1086 Query: 718 MDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENI---ESELSKY 774 + K E + ++ E KI Q Q + K QE + N E + + Sbjct: 1087 FGINQKYETQNLLELEEPEIKIVQMIQQP-QIELDSQKKNQEEVFELGNAADEEDDEEEL 1145 Query: 775 KSRICRLEES---IAVMEDRR-YSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVL 830 K +C + ++ I + D+ ++ + +Q + E K E E +L+N L + Sbjct: 1146 KQVVCEIVQNPPNIQIELDQGDNNIPHQQNQTNNLGVENPK---EKPKVEKDLLNLLDLQ 1202 Query: 831 MDHDRVVEKQL---LEIEHENKELQKKNQILLEENQNLQISLSDMQQHY 876 +V+ + LE++ EN EL++ +Q L EE ++I L Q + Sbjct: 1203 EPVTEIVQVEQYVQLELDQENFELKEPDQQLEEE---VEIQLDKKPQEF 1248 >UniRef50_A4QRL5 Cluster: Putative uncharacterized protein; n=1; Magnaporthe grisea|Rep: Putative uncharacterized protein - Magnaporthe grisea (Rice blast fungus) (Pyricularia grisea) Length = 1645 Score = 122 bits (295), Expect = 6e-26 Identities = 229/1141 (20%), Positives = 469/1141 (41%), Gaps = 125/1141 (10%) Query: 497 NVKDLIEKLK-SAEEQITQLNDEIDAANKNMIK--VKSNHKLKLKQ--MQKTIDNFSK-V 550 NV D IEK + +I L D + A + +K N +LK+ M++ + + K + Sbjct: 180 NVIDRIEKENFGLKLKIHFLEDALRRAGPGFSEAALKENTELKVDSVTMKRELHRYKKHL 239 Query: 551 SDSNKEIVRLTEELHHLSQKVAELEEEKGN------LQLHLVDYDSGRMIESDVYKKMIE 604 + + K++ +++ + K + + +G LQ L + D+G D+ +K+ + Sbjct: 240 TSAEKDLEAYRQQILEMQDKFKKRQANEGQRLEIERLQQALEEKDAGL---EDLQQKLDQ 296 Query: 605 MENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHL 664 E + K + + D + ++ Q DE+ED I + S+ + V L Sbjct: 297 GEKELDRIEKLQDEIGDLEADNRAKDQLIGQHEDEIEDLKLRIQAAEDKAKDSQRRMVEL 356 Query: 665 EEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKL 724 EE+ A S+ E IE+L+ D ++ L+N+ E+ +KLQ+ + D D+ Sbjct: 357 EEKAQA-SSKLAEAKEAIEDLEAD-------VRRLQNELEEYKDKLQDAV----DAKDRA 404 Query: 725 EKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEES 784 E E++ E +A + T+ G+ +++E+ I ++ E+ +S + + Sbjct: 405 EG-DLEELQEEMAN------KSVVTK-GLSRQVEEK---IARLQDEVEDARSNLATVNNR 453 Query: 785 IAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEI 844 E+ L+RK + + ++ + + DEL L DH +++ + + Sbjct: 454 YQDKENEVEDLKRKLKESRQERETFERENRSLSAEVDELQGDLRSANDHKSLLQTRHDAL 513 Query: 845 EHENKELQKKNQILLEENQNLQISLSDMQQH---YNALVEKANRTDL--AESESTKYQTQ 899 E+ LQ+ L + L+ SL +QH V + NRT++ SE + Q + Sbjct: 514 TKESASLQRDVSRLQRDTAALEASLEQEKQHALQIERTVREQNRTEINRLRSEISDLQAR 573 Query: 900 LRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDK-KVLNEKYEKNIEYVT 958 R+ E + + T + Q K E+E L+ + + +++ IR+K + + +EK + Sbjct: 574 AREAEEDRQHATQSDRISRDQLKDEVERLKDDIS-DLQAQIREKDNMYDNDHEKWETEIR 632 Query: 959 QLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQ---TQSPDYTEQYINEINKLN 1015 LEA+ + L +++L L K + Q T++ + ++ ++ Sbjct: 633 NLEAERDRAEERANGLQRTIDKLRATEGALSTKEAKLQHIIDTETERHRKEEAVLSRQVE 692 Query: 1016 ALLKQKDE----------EIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQ 1065 +L K D E+ ++ +++ AQV Y S V E + +EE+ + Sbjct: 693 SLQKTLDSRQTMLEDLRIELSSVREQLRQAQVDYQSEVDKVEGLEDELELLQVELEEQSE 752 Query: 1066 RVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDA 1125 + S+ L +K+ E L R+Q +E T + + S I+ + D Sbjct: 753 KASRDLEQAKRECENL----RQQLQSAQESAATSVRQSNTVSHEVARHNSEHIQRLKDQL 808 Query: 1126 NNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKI----IQLETL 1181 + + +E+ +LQEQ A +NTEL + + E+L Sbjct: 809 AE---------------STTKFSKTTKEKQLLQEQLAGVNTELYSVRASLAESQAERESL 853 Query: 1182 NTEL-----TGHD--VVNQEQIN------QLKSKLEQLNTENDNLLSTVAELRSSISSA- 1227 ++L +G D VVNQE ++ +L S++ +L EN +L + ++ + + A Sbjct: 854 ESDLRLAKQSGQDVHVVNQELVDLRTTKTKLDSEVRRLREENKSLAGRLRQVEAELQDAK 913 Query: 1228 VDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQ-SSTQEETNKI 1286 + + + + + L ++ L Q + S+ ++ ++ Q++ K Sbjct: 914 LHGQDTALLDQERMDLLTAKSKLDGDVRRLGDQNRSLTSRLREVETELRLLKQQDDHTKQ 973 Query: 1287 VTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXX 1346 + +++V + K + E LR ++E+ + ++ ++EIE+E V Sbjct: 974 LELQRVDIISAKSR-LENELRRVKEENVVLTSE----KAEIENELVRVSKNQGEDTLDLN 1028 Query: 1347 XXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELT 1406 LRT K E + + E+N QL++S R E + LT Sbjct: 1029 FERITLRTA----KNKLETELRCLKEKNRQLEESLLELERQLDEENERAAQEEER---LT 1081 Query: 1407 HQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLT----YEKESELAIL 1462 H++ +++ Q T T ++R + + +++ YE R+ T E S+L+IL Sbjct: 1082 HEILELQAKLRQSTDTQAQTASRR--KIRELERRIDNYEARLAITTNIVDVEGNSDLSIL 1139 Query: 1463 RLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKAL----EEEVAK 1518 R + A E E E + +L +I++ + + AE+ + L + Sbjct: 1140 RRDI-TTARQKERDFAEREAAHKSTVRDLKRQISDLERVVHE-AEMQRLLASPADARTPS 1197 Query: 1519 TNEMQTALENQEIEIV-----TLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLD 1573 T + + A ++ + L + + A ++Q + D ++QLD Sbjct: 1198 TRKSELAQLRHQLTLAHQVGQDLKQALREAERDADAVKDELQARIGDLEDQAASLEQQLD 1257 Query: 1574 N 1574 + Sbjct: 1258 D 1258 Score = 100 bits (240), Expect = 3e-19 Identities = 171/880 (19%), Positives = 386/880 (43%), Gaps = 78/880 (8%) Query: 483 EQLKQELNDEIKDVNVKDLIEKLKSAE---EQITQLNDEI---DAANKNMIKVKSNHKLK 536 E+L+Q L + KD ++DL +KL E ++I +L DEI +A N+ ++ H+ + Sbjct: 274 ERLQQALEE--KDAGLEDLQQKLDQGEKELDRIEKLQDEIGDLEADNRAKDQLIGQHEDE 331 Query: 537 LKQMQKTIDNF-SKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIE 595 ++ ++ I K DS + +V L EE S K+AE +E +L+ + + Sbjct: 332 IEDLKLRIQAAEDKAKDSQRRMVEL-EEKAQASSKLAEAKEAIEDLEADVRRLQNELEEY 390 Query: 596 SDVYKKMIEMENLAETRLKAISLLESQKFDLVQEL-HILQQK----YDEVEDKLADISQL 650 D + ++ ++ AE L+ + + K + + L +++K DEVED ++++ + Sbjct: 391 KDKLQDAVDAKDRAEGDLEELQEEMANKSVVTKGLSRQVEEKIARLQDEVEDARSNLATV 450 Query: 651 QSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKL 710 + E + L+ ++ ++ +L + ++L G ++ + K + + Sbjct: 451 NNRYQDKENEVEDLKRKLKESRQERETFERENRSLSAEVDELQGDLRSANDHKSLLQTRH 510 Query: 711 QNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERD-LYIENIES 769 +E+ L + ++ + + L A + E+Q +Q I+ ++E++ I + S Sbjct: 511 DALTKESASLQRDVSRLQRD-TAALEASLEQEKQHALQ----IERTVREQNRTEINRLRS 565 Query: 770 ELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAV 829 E+S ++R E EDR+++ + +D++ + + E +D++ + A Sbjct: 566 EISDLQARAREAE------EDRQHATQ--SDRI-----SRDQLKDEVERLKDDISDLQAQ 612 Query: 830 LMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNAL-VEKANRTDL 888 + + D + + + E E + L+ + E LQ ++ ++ AL ++A + Sbjct: 613 IREKDNMYDNDHEKWETEIRNLEAERDRAEERANGLQRTIDKLRATEGALSTKEAKLQHI 672 Query: 889 AESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNE 948 ++E+ +++ + E+ L R Q + ++ +EDL IE ++ + +R +V Sbjct: 673 IDTETERHRKE----EAVLSRQVESLQKTLDSRQTMLEDLRIELSS-VREQLRQAQV--- 724 Query: 949 KYEKNIEYVTQLEAQLQ----EYKNNIENLNMNVEELNK--MNLELIDKHVQKQQTQSPD 1002 Y+ ++ V LE +L+ E + E + ++E+ + NL + Q+ S Sbjct: 725 DYQSEVDKVEGLEDELELLQVELEEQSEKASRDLEQAKRECENLRQQLQSAQESAATSVR 784 Query: 1003 YTEQYINEINKLNA--LLKQKDE--EIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLE 1058 + +E+ + N+ + + KD+ E K + ++ ++L L Sbjct: 785 QSNTVSHEVARHNSEHIQRLKDQLAESTTKFSKTTKEKQLLQEQLAGVNTELYSVRASLA 844 Query: 1059 NMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTI 1118 + E + + L +KQ +++ ++ +E D ++ K TKL E+ + E ++ + Sbjct: 845 ESQAERESLESDLRLAKQSGQDVHVVNQELVD-LRTTK-TKLDSEVRRLREENKSLAGRL 902 Query: 1119 EPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQ-------EQSAKLNTELQEC 1171 + + + L QE + + +S L +Q+ L + L+E Sbjct: 903 RQVEAELQD-----AKLHGQDTALLDQERMDLLTAKSKLDGDVRRLGDQNRSLTSRLREV 957 Query: 1172 YTKIIQLE-----TLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISS 1226 T++ L+ T EL D+++ + ++L+++L ++ EN L S AE+ + + Sbjct: 958 ETELRLLKQQDDHTKQLELQRVDIISAK--SRLENELRRVKEENVVLTSEKAEIENELVR 1015 Query: 1227 AVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKI 1286 +G + +L + + R A K E ELR L + E+ L ++ EE + Sbjct: 1016 VSKNQGEDTLDLNFERITLRTAK-NKLETELRC-LKEKNRQLEESLLELERQLDEENERA 1073 Query: 1287 VTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSE 1326 E+ L +++ + + LR + A ++ +I E Sbjct: 1074 AQEEE--RLTHEILELQAKLRQSTDTQAQTASRRKIRELE 1111 Score = 64.1 bits (149), Expect = 3e-08 Identities = 187/1167 (16%), Positives = 472/1167 (40%), Gaps = 116/1167 (9%) Query: 213 DTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHS 272 + K+ + ++ + ++ E ++ K +L +++KD LEE Sbjct: 368 EAKEAIEDLEADVRRLQNELEEYKDKLQDAVDAKDRAEGDLEE----------------- 410 Query: 273 KLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEE-KGSLEIANMTELTKKIELL 331 L +E+ L++Q E + E+E+ + +L N K+ E + Sbjct: 411 -LQEEM-------ANKSVVTKGLSRQVEEKIARLQDEVEDARSNLATVNNRYQDKENE-V 461 Query: 332 EHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSS 391 E L +++++ +E E T E++++S+ + +S + S +++ L+ Sbjct: 462 EDLKRKLKESRQERE----TFERENRSLSAEVDELQG--DLRSANDHKSLLQTRHDALTK 515 Query: 392 ETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQ 451 E+ + D + + A LE ++ + + E + E++ A+ Sbjct: 516 ESASLQRDVSRLQRDTAALEASLEQEKQHALQIERTVREQNRTEINRLRSEISDLQARAR 575 Query: 452 LQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQ 511 E +QH T ++ ++ ++QLK E+ + +KD ++ DL +++ + Sbjct: 576 EAEEDRQH---------ATQSDRIS-----RDQLKDEV-ERLKD-DISDLQAQIREKDNM 619 Query: 512 ITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKV 571 +++ + +N+ + + + +Q+TID +R TE LS K Sbjct: 620 YDNDHEKWETEIRNLEAERDRAEERANGLQRTIDK-----------LRATEGA--LSTKE 666 Query: 572 AELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELH 631 A+L+ H++D ++ R + + ++E+L +T ++LE + +L Sbjct: 667 AKLQ--------HIIDTETERHRKEEAVLSR-QVESLQKTLDSRQTMLEDLRIELSSVRE 717 Query: 632 ILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQ 691 L+Q + + ++ + L+ + E+ V LEEQ + S ++ ENL+ + Sbjct: 718 QLRQAQVDYQSEVDKVEGLEDE---LELLQVELEEQSEKASRDLEQAKRECENLRQQLQS 774 Query: 692 LYGTIKDLENDKEDIMNKLQNYIQENMD-LTDKLEKMSAEKISELL--AKINHEEQSKIQ 748 + + +++ + E++ L D+L + S K S+ ++ E+ + + Sbjct: 775 AQESAATSVRQSNTVSHEVARHNSEHIQRLKDQLAE-STTKFSKTTKEKQLLQEQLAGVN 833 Query: 749 TQ-FGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQ 807 T+ + + A + E E++ES+L K + + D R + + K D L+ Sbjct: 834 TELYSVRASLAESQAERESLESDLRLAKQSGQDVHVVNQELVDLR-TTKTKLDSEVRRLR 892 Query: 808 EKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQI 867 E+ K+ + Q + + + +++++ +++ +L + L ++N++L Sbjct: 893 EENKSLAGRLRQVEAELQDAKLHGQDTALLDQERMDLLTAKSKLDGDVRRLGDQNRSLTS 952 Query: 868 SLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIED 927 L +++ L ++ + T E + + LE+ L+R+ E+ ++ +K EIE+ Sbjct: 953 RLREVETELRLLKQQDDHTKQLELQRVDIISAKSRLENELRRVKEEN-VVLTSEKAEIEN 1011 Query: 928 LEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLE 987 E K + + N E +T L + + + L +L + LE Sbjct: 1012 ---------ELVRVSKNQGEDTLDLNFERIT-LRTAKNKLETELRCLKEKNRQLEESLLE 1061 Query: 988 LIDKHVQKQQTQSPDYTEQYINEINKLNALLKQK--DEEIIALNQKINNAQVSYMSMVSD 1045 L ++ + ++ ++ E+ +EI +L A L+Q + A +KI + + + Sbjct: 1062 L-ERQLDEENERAAQEEERLTHEILELQAKLRQSTDTQAQTASRRKIRELE----RRIDN 1116 Query: 1046 YESKLAQFTTKLENME--EEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFE 1103 YE++LA TT + ++E ++ + + + ++Q + +++LK E Sbjct: 1117 YEARLA-ITTNIVDVEGNSDLSILRRDITTARQKERDFAEREAAHKSTVRDLKRQISDLE 1175 Query: 1104 MNIPKTE-GMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQER-----SVL 1157 + + E +++S + + + Q+ ++ ++E +V Sbjct: 1176 RVVHEAEMQRLLASPADARTPSTRKSELAQLRHQLTLAHQVGQDLKQALREAERDADAVK 1235 Query: 1158 QEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTV 1217 E A++ + + QL+ ++ + + + K+E+ E D + + Sbjct: 1236 DELQARIGDLEDQAASLEQQLDDARAAAEEAAAASETALVKYRGKVERYRRERDQYAAAL 1295 Query: 1218 AELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQS 1277 E++ + + +++ + D + +++ +FE + + + Sbjct: 1296 EEMQHTDHGSALTARTDVSN-------EERRDLHGMLRKAQIEADSFEREVREHKALAEE 1348 Query: 1278 STQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXX 1337 ++ + + +E+V + + + E +R ++ A ++ E++R++ E E Sbjct: 1349 LSKAQETLCLKLERVRGERAVYRKEAERMR--RDLRAVELSNAELVRAKDEAEGALVANA 1406 Query: 1338 XXXXXXXXXXXXXDLRTENQSYKQMQE 1364 +EN++ + ++E Sbjct: 1407 LILASRDAAAIAPPANSENKAAETVKE 1433 >UniRef50_UPI00015B5411 Cluster: PREDICTED: similar to SD07366p; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to SD07366p - Nasonia vitripennis Length = 1535 Score = 122 bits (294), Expect = 8e-26 Identities = 159/853 (18%), Positives = 360/853 (42%), Gaps = 53/853 (6%) Query: 492 EIKDVNVKDLIEKLKSAEEQITQLND-EIDAAN-KNMIKVKSNHKLKLKQMQKTIDNFSK 549 ++ + ++ +E+ K +E I + + ++D N + +K+ ++ +L+ + Sbjct: 569 DVLESELRVSLERCKGLDENIELIEELKLDLENARRELKIALSNNKRLENSLTILQETKN 628 Query: 550 VSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLA 609 D++ E++ +E Q A+L+ L D D+ + + K E ++L Sbjct: 629 EVDADNEVLSREKE-----QLEADLKLLSSGSDLKKSDGDALAELREQLKKSKEEKDDLE 683 Query: 610 ETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQL--QSDQVCSEIKSVHLEEQ 667 + + + +L Q L L+ E+E D +L ++ ++ + +E Sbjct: 684 YD-------IRNMRNELDQSLEQLEANRAEIEKLQLDNERLAKENGKLLDQFSETQ-KEN 735 Query: 668 IDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKM 727 +D + E+ L+ + L +K++L T++ L + +E I+ L+N EN L + K+ Sbjct: 736 LDKVDLLNTEMTLLQQELDGNKDELEKTMRYLSDMEEKILT-LKN---ENERLNVEASKI 791 Query: 728 SAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAV 787 +I L K EE+S T+ +DA +++ + +E ++S +S RL++ + Sbjct: 792 KENEIEFLKLKEQLEERSLDHTKEELDAALKK----LSELEEKVSMLESENKRLQDELIR 847 Query: 788 MEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHE 847 D ++ + +L ++EKQK E E+E N L + E + +E E Sbjct: 848 TSD----VDSENKRLVEAIEEKQK---EIAKNEEEAANVTTKL----KCTENYISSLEDE 896 Query: 848 NKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNL 907 ++ L+ K + +EN++ + + +++Q + E+ + + S+ YQT+L L+ Sbjct: 897 SQILESKLAQVDQENESAKKEIEELRQQLES--ERRQKEADGKELSSTYQTELDKLKGEN 954 Query: 908 KRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEY 967 +R+ E L+V+K+ + + Q+ ++ L ++ + + + L+A + + Sbjct: 955 ERLKSELDKLLVEKRDVEVNTRASSDAQVSLTEEERSQLLDQLSEKFKEIENLKATISKD 1014 Query: 968 KNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTE--QYINEINKLNALLKQKDEEI 1025 K++ + VE L+++ ++ ++ T E + + + + + Q EI Sbjct: 1015 KDSAQMARETVENLSQLISSKDNELIKLNATVDMFRNERDEVVKLVQEKHNESLQYHAEI 1074 Query: 1026 IALNQKINNAQVSYMSMVSDYESKLAQFTTKLENM---EEEMQRVSKQLL---DSKQHNE 1079 L Q I++ + +++ ++ LA K + + E+Q V ++L +S H E Sbjct: 1075 QRLTQLISDQTANLQKAIAEKDATLASLQEKESQLLWTQNELQVVKQRLQNIEESNNHGE 1134 Query: 1080 ELQILVREQ-DDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXX 1138 I + L+E E I + + I ++ +A + + Sbjct: 1135 RCGIAEHTLLSKHVSTLEEKSKAMEAAILQDQSNI--RYLQEQLTEAQSKETIALKEVDR 1192 Query: 1139 XXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQ 1198 V+ E + +E +E L L + K L+ +T T V +Q+ Sbjct: 1193 LRNHLVEMEANYTEEALQSEEIQRTLQARLMQAEEK---LKNSSTMYTSASVRANQQVET 1249 Query: 1199 LKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELR 1258 L+ +L + + D+L + ++ + S + + +Q +E D Q +LR Sbjct: 1250 LQQQLALIVQQRDDLQNKISSAEDKVLS-YSASLTNLQLVLEQFQRDKEKDIQAATEKLR 1308 Query: 1259 VQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVIN 1318 V+L K ++L+ + S ++ + + L +L+ K E + L ++ + Sbjct: 1309 VELQQSYKKQDELVSEITSLKEQLAEAKECLRAASRLTEQLEKKSERIELLNQEVNRLTE 1368 Query: 1319 QIEILRSEIEDEK 1331 + IE+ K Sbjct: 1369 LVNTADQRIEEAK 1381 Score = 111 bits (266), Expect = 2e-22 Identities = 245/1241 (19%), Positives = 514/1241 (41%), Gaps = 104/1241 (8%) Query: 338 IRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTA-SKMKSPWSQLSSE--TL 394 IR LEN+ + ++ S + GR+ + +K++ L +E +L Sbjct: 196 IRSALMALENESEQLQGSAEKTDSVGYDAEGKSRNEKGRDESEAKLRRRVEDLEAENQSL 255 Query: 395 NQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQL 454 +Q ++ ++K +E V+ SL ++L K + + GK + Q Q Sbjct: 256 SQSIEE-LDKQNAESIERVL-SLKEELQKKHHSLQGAYEQLYVEYNQALGKIENLQQQQ- 312 Query: 455 EHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQ 514 + QQ + P L N ++ + QLK + EI+ E S E++ + Sbjct: 313 QQQQQQQKPELSKA-PNKSSLDTAVQTLAQLKLDKETEIRPAKEDKQTEISTSKEDKEVE 371 Query: 515 LN----DEIDAAN--KNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIV----RLTEEL 564 ++ D+ D A+ K + + N L+ F V+ E+ L +L Sbjct: 372 VDLKPEDQQDLASELKKVNDILKNAPLEPSNEHLNDSVFVAVARQFVELKWKKETLERKL 431 Query: 565 HHLSQKVAELEEEKGNLQLHLVDYDSG-RMIESDVYKKMIEMENLAETRLKAISLLESQK 623 S+++ E +E + +LQ+ D + + +V + ++ E + ++ LE++ Sbjct: 432 TEQSRQLKETQELRDSLQIDCEDMQTNIESLVMEVQHLKSNLPSIPEASEERVASLETET 491 Query: 624 FDLVQELHILQQKYDEVEDKLADI-SQLQSD------QVCSEIKSVHLEEQIDALSASKK 676 L E+ L++ ++ +L I + ++ D ++ + I+S+ E+ S S K Sbjct: 492 ESLQAEILALRKSKADMSSELKAIKAAIREDGGGGGVELATRIESLLAEQN---KSKSSK 548 Query: 677 ELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELL 736 + A +++ + L I LE++ + + + + EN++L ++L K+ E L Sbjct: 549 DPAELLQATLDENTALRRRIDVLESELRVSLERCKG-LDENIELIEEL-KLDLENARREL 606 Query: 737 AKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLE 796 KI +++ I +QE ++ LS+ K + LE + ++ + Sbjct: 607 -KIALSNNKRLENSLTI---LQETKNEVDADNEVLSREKEQ---LEADLKLLSSGSDLKK 659 Query: 797 RKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQ 856 D L ++ +K+ E E ++ N L +E EIE +LQ N+ Sbjct: 660 SDGDALAELREQLKKSKEEKDDLEYDIRNMRNELDQSLEQLEANRAEIE----KLQLDNE 715 Query: 857 ILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLK---RITHE 913 L +EN L S+ Q+ E ++ DL +E T Q +L + L+ R + Sbjct: 716 RLAKENGKLLDQFSETQK------ENLDKVDLLNTEMTLLQQELDGNKDELEKTMRYLSD 769 Query: 914 HQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQ-LEAQLQEYKNNIE 972 + I+ K E E L +E + E+ I K+ + E+++++ + L+A L++ + Sbjct: 770 MEEKILTLKNENERLNVEASKIKENEIEFLKLKEQLEERSLDHTKEELDAALKK----LS 825 Query: 973 NLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKI 1032 L V L N L D+ ++ S + ++ + I + + + +EE + K+ Sbjct: 826 ELEEKVSMLESENKRLQDELIRTSDVDSEN--KRLVEAIEEKQKEIAKNEEEAANVTTKL 883 Query: 1033 NNAQVSYMSMVSD----YESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNE----ELQIL 1084 + +Y+S + D ESKLAQ + E+ ++E++ + +QL ++ E EL Sbjct: 884 KCTE-NYISSLEDESQILESKLAQVDQENESAKKEIEELRQQLESERRQKEADGKELSST 942 Query: 1085 VREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKV 1144 + + D++K E +L E++ E + SD ++ K Sbjct: 943 YQTELDKLKGENE-RLKSELDKLLVEKRDVEVNTRASSDAQVSLTEEERSQLLDQLSEKF 1001 Query: 1145 QEEEEFIQERSVLQEQSAKLNTELQECYTKII-----QLETLNTELTGHDVVNQEQINQL 1199 +E E ++ + SA++ E E +++I +L LN + E + + Sbjct: 1002 KEIEN-LKATISKDKDSAQMARETVENLSQLISSKDNELIKLNATVDMFRNERDEVVKLV 1060 Query: 1200 KSKLE---QLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHE 1256 + K Q + E L +++ +++ A+ ++ +A L ++E+ T++E Sbjct: 1061 QEKHNESLQYHAEIQRLTQLISDQTANLQKAIAEKDATLASL-----QEKESQLLWTQNE 1115 Query: 1257 LRV---QLSAFESKY---------EQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEE 1304 L+V +L E E L S ST EE +K + + Q+ ++ +E Sbjct: 1116 LQVVKQRLQNIEESNNHGERCGIAEHTLLSKHVSTLEEKSKAMEAA-ILQDQSNIRYLQE 1174 Query: 1305 HLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQ--- 1361 L Q K + +++ LR+ + + + + L + K Sbjct: 1175 QLTEAQSKETIALKEVDRLRNHLVEMEANYTEEALQSEEIQRTLQARLMQAEEKLKNSST 1234 Query: 1362 MQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDS--EIYQK 1419 M + + N++ L++ +++ AE KVL + L E +Q+ Sbjct: 1235 MYTSASVRANQQVETLQQQLALIVQQRDDLQNKISSAEDKVLSYSASLTNLQLVLEQFQR 1294 Query: 1420 THEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKE 1479 E I E ++Q + ++ + ++T KE +LA + + + E ++K+ Sbjct: 1295 DKEKDIQAATEKLRVE-LQQSYKKQDELVSEITSLKE-QLAEAKECLRAASRLTEQLEKK 1352 Query: 1480 SEIERVKLIEELNVKITESV-SLNKQVAELNKALEEEVAKT 1519 S ER++L+ + ++TE V + ++++ E K+ E +V ++ Sbjct: 1353 S--ERIELLNQEVNRLTELVNTADQRIEEAKKSGEGKVDRS 1391 Score = 107 bits (256), Expect = 3e-21 Identities = 210/1131 (18%), Positives = 467/1131 (41%), Gaps = 78/1131 (6%) Query: 461 EGPSLIHVGTNTEDVNEIAKVQ--EQLKQELNDEIKDVNVKDL--IEKLKSAEEQITQLN 516 EG S G + + +V+ E Q L+ I++++ ++ IE++ S +E++ + + Sbjct: 225 EGKSRNEKGRDESEAKLRRRVEDLEAENQSLSQSIEELDKQNAESIERVLSLKEELQKKH 284 Query: 517 DEIDAANKNMIKVKSNHKL-KLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELE 575 + A + + V+ N L K++ +Q+ + L Q +A+L+ Sbjct: 285 HSLQGAYEQLY-VEYNQALGKIENLQQQQQQQQQQQKPELSKAPNKSSLDTAVQTLAQLK 343 Query: 576 EEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQ 635 +K ++ D I + K +E++ E + S E +K + + + L+ Sbjct: 344 LDK-ETEIRPAKEDKQTEISTSKEDKEVEVDLKPEDQQDLAS--ELKKVNDILKNAPLEP 400 Query: 636 KYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGT 695 + + D + Q ++ + K LE ++ S KE + ++L++D E + Sbjct: 401 SNEHLNDSVFVAVARQFVEL--KWKKETLERKLTEQSRQLKETQELRDSLQIDCEDMQTN 458 Query: 696 IKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDA 755 I+ L + + + + L + + + + LE + +E+LA + + + I A Sbjct: 459 IESLVMEVQHLKSNLPSIPEASEERVASLETETESLQAEILALRKSKADMSSELK-AIKA 517 Query: 756 KIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSE 815 I+E D +E +RI ES+ +++ S + A+ L + L E Sbjct: 518 AIRE-DGGGGGVE-----LATRI----ESLLAEQNKSKSSKDPAELLQATLDENTALRRR 567 Query: 816 YTIQEDEL---VNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDM 872 + E EL + R L ++ ++E+ L++E+ +EL+ I L N+ L+ SL+ + Sbjct: 568 IDVLESELRVSLERCKGLDENIELIEELKLDLENARRELK----IALSNNKRLENSLTIL 623 Query: 873 QQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEF 932 Q+ N V+ N E E + +L S+LK+ + + ++ K+ ++ + + Sbjct: 624 QETKNE-VDADNEVLSREKEQLEADLKLLSSGSDLKKSDGDALAELREQLKKSKEEKDDL 682 Query: 933 NTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKH 992 I + + E+ E N + +L+ + L E K NL+ +D Sbjct: 683 EYDIRNMRNELDQSLEQLEANRAEIEKLQLDNERLAKENGKLLDQFSETQKENLDKVDL- 741 Query: 993 VQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQ 1052 + + T + +E+ K L +E+I+ L + V S + + E + + Sbjct: 742 LNTEMTLLQQELDGNKDELEKTMRYLSDMEEKILTLKNENERLNVE-ASKIKENEIEFLK 800 Query: 1053 FTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGM 1112 +LE E + ++L + + EL+ V + + K L++ +L ++ Sbjct: 801 LKEQLE--ERSLDHTKEELDAALKKLSELEEKVSMLESENKRLQD-ELIRTSDVDSENKR 857 Query: 1113 IISSTIEPMSDDANNVDXXXXXXXX---XXXXLKVQEEEEFIQERSVLQ--EQSAKLNTE 1167 ++ + E + A N + + E+E I E + Q +++ E Sbjct: 858 LVEAIEEKQKEIAKNEEEAANVTTKLKCTENYISSLEDESQILESKLAQVDQENESAKKE 917 Query: 1168 LQECYTKIIQLETLNTELTGHDVVN--QEQINQLKSKLEQLNTENDNLLSTVAELRSSIS 1225 ++E ++ + E E G ++ + Q ++++LK + E+L +E D LL ++ + Sbjct: 918 IEELRQQL-ESERRQKEADGKELSSTYQTELDKLKGENERLKSELDKLLVEKRDVEVNTR 976 Query: 1226 SAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQ---EE 1282 ++ D + E Q L Q F++ E+ L+ +S + + ++V++ +Q + Sbjct: 977 ASSDAQVSLTEEERSQLLDQLSEKFKEIEN-LKATISKDKDSAQMARETVENLSQLISSK 1035 Query: 1283 TNKIVTMEQVTSLQNKLQDK------EEHLRNLQEKYADVINQIEILRSEIEDEKVAFXX 1336 N+++ + + +D+ E+H +LQ +A++ +++ + + + A Sbjct: 1036 DNELIKLNATVDMFRNERDEVVKLVQEKHNESLQY-HAEIQRLTQLISDQTANLQKAIAE 1094 Query: 1337 XXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVN 1396 L T+N+ Q+ +Q + NI E N ++ + Sbjct: 1095 KDATLASLQEKESQLLWTQNEL--QVVKQRLQNIEESNNHGERCGIAEHTLLSKHVSTLE 1152 Query: 1397 DA----EAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLT 1452 + EA +L+ + ++ + + TI L E + +R LVE E + Sbjct: 1153 EKSKAMEAAILQDQSNIRYLQEQLTEAQSKETIALK----EVDRLRNHLVEMEANYTEEA 1208 Query: 1453 YEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKAL 1512 + E L+ ++ MQ E KL + + SV N+QV L + L Sbjct: 1209 LQSEEIQRTLQARL---------MQAEE-----KLKNSSTMYTSASVRANQQVETLQQQL 1254 Query: 1513 EEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASD 1563 V + +++Q + + E ++++ + +TNLQ ++ +K + A++ Sbjct: 1255 ALIVQQRDDLQNKISSAEDKVLSYSASLTNLQLVLEQFQRDKEKDIQAATE 1305 Score = 105 bits (251), Expect = 1e-20 Identities = 160/842 (19%), Positives = 356/842 (42%), Gaps = 60/842 (7%) Query: 310 IEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPL 369 +E + + + L + IEL+E L + +EL+ L + +K + + Sbjct: 571 LESELRVSLERCKGLDENIELIEELKLDLENARRELKIAL----SNNKRLENSLTILQET 626 Query: 370 ISRKSGRNTASKMKSPWSQLSSETLNQDTD-KKINKNEIAKLEMVIQSLNKDLVDKEYVI 428 + N + + + L+ +D KK + + +A+L ++ ++ D EY I Sbjct: 627 KNEVDADNEVLSREKEQLEADLKLLSSGSDLKKSDGDALAELREQLKKSKEEKDDLEYDI 686 Query: 429 SEKDTXXXXXXXXXXGKDTLIAQLQLEHQQ-HMEGPSLIHVGTNTEDVN----EIAKVQE 483 I +LQL++++ E L+ + T+ N ++ + Sbjct: 687 RNMRNELDQSLEQLEANRAEIEKLQLDNERLAKENGKLLDQFSETQKENLDKVDLLNTEM 746 Query: 484 QLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKT 543 L Q+ D KD ++ + L EE+I L +E + N K+K N +++ ++++ Sbjct: 747 TLLQQELDGNKD-ELEKTMRYLSDMEEKILTLKNENERLNVEASKIKEN-EIEFLKLKEQ 804 Query: 544 IDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHL-----VDYDSGRMIES-- 596 ++ S + + +E+ ++L L +KV+ LE E LQ L VD ++ R++E+ Sbjct: 805 LEERS-LDHTKEELDAALKKLSELEEKVSMLESENKRLQDELIRTSDVDSENKRLVEAIE 863 Query: 597 DVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVC 656 + K++ + E A + E+ L E IL+ K +V D+ + ++ + +++ Sbjct: 864 EKQKEIAKNEEEAANVTTKLKCTENYISSLEDESQILESKLAQV-DQENESAKKEIEELR 922 Query: 657 SEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQE 716 +++S +++ D S ++ LK + E+L + L +K D+ + Sbjct: 923 QQLESERRQKEADGKELS-STYQTELDKLKGENERLKSELDKLLVEKRDVEVNTRASSDA 981 Query: 717 NMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKS 776 + LT++ +++SE K E K D+ R+ +EN+ +S + Sbjct: 982 QVSLTEEERSQLLDQLSE---KFKEIENLKATISKDKDSAQMARET-VENLSQLISSKDN 1037 Query: 777 RICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRV 836 + +L ++ + + R D++ +QEK +Y + L ++ D Sbjct: 1038 ELIKLNATVDMFRNER-------DEVVKLVQEKHNESLQYHAEIQRLTQ---LISDQTAN 1087 Query: 837 VEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKY 896 ++K + E + LQ+K LL LQ+ +Q +E++N + E Sbjct: 1088 LQKAIAEKDATLASLQEKESQLLWTQNELQVVKQRLQN-----IEESN--NHGERCGIAE 1140 Query: 897 QTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEY 956 T L S L+ + + I+Q + I L+ Q+ A + + ++ ++ + Sbjct: 1141 HTLLSKHVSTLEEKSKAMEAAILQDQSNIRYLQ----EQLTEAQSKETIALKEVDRLRNH 1196 Query: 957 VTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNA 1016 + ++EA E E + + + M E K+ T + Q + + + A Sbjct: 1197 LVEMEANYTEEALQSEEIQRTL-QARLMQAEEKLKNSSTMYTSASVRANQQVETLQQQLA 1255 Query: 1017 LLKQKDEEIIALNQKINNAQ---VSYMSMVSDYESKLAQF-TTKLENMEEEMQRVSKQLL 1072 L+ Q+ ++ L KI++A+ +SY + +++ + L QF K ++++ +++ +L Sbjct: 1256 LIVQQRDD---LQNKISSAEDKVLSYSASLTNLQLVLEQFQRDKEKDIQAATEKLRVELQ 1312 Query: 1073 DSKQHNEELQILVREQDDQIKELKE-----TKLTFEMNIPKTEGMIISSTIEPMSDDANN 1127 S + +EL + +Q+ E KE ++LT ++ +++ + +++ N Sbjct: 1313 QSYKKQDELVSEITSLKEQLAEAKECLRAASRLTEQLEKKSERIELLNQEVNRLTELVNT 1372 Query: 1128 VD 1129 D Sbjct: 1373 AD 1374 Score = 98.3 bits (234), Expect = 2e-18 Identities = 166/790 (21%), Positives = 349/790 (44%), Gaps = 66/790 (8%) Query: 298 QSIEPSCEEKTEIEE-KGSLEIA--NMTELTKKIELLEHLNCQIRQTNKELENKLATMGT 354 ++IE E K ++E + L+IA N L + +L+ ++ N+ L + + Sbjct: 587 ENIELIEELKLDLENARRELKIALSNNKRLENSLTILQETKNEVDADNEVLSREKEQLEA 646 Query: 355 ESKAVSSPSK-KGSPLISRKSGRNTASKMKSPWSQLSSETLNQ--DTDKKI-----NKNE 406 + K +SS S K S + R K K L + N + D+ + N+ E Sbjct: 647 DLKLLSSGSDLKKSDGDALAELREQLKKSKEEKDDLEYDIRNMRNELDQSLEQLEANRAE 706 Query: 407 IAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLI 466 I KL++ + L K+ SE + TL+ Q +L+ + ++ Sbjct: 707 IEKLQLDNERLAKENGKLLDQFSETQKENLDKVDLLNTEMTLLQQ-ELDGNKDELEKTMR 765 Query: 467 HVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNM 526 ++ E + + E+L E + +IK+ ++ L K + E + +E+DAA K + Sbjct: 766 YLSDMEEKILTLKNENERLNVEAS-KIKENEIEFLKLKEQLEERSLDHTKEELDAALKKL 824 Query: 527 IKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHL- 585 +++ + + ++ D + SD + E RL E + +++A+ EEE N+ L Sbjct: 825 SELEEKVSMLESENKRLQDELIRTSDVDSENKRLVEAIEEKQKEIAKNEEEAANVTTKLK 884 Query: 586 --VDYDSGRMIESDVYK-KMIEMENLAETRLKAI----SLLESQKFDLVQELHILQQKYD 638 +Y S ES + + K+ +++ E+ K I LES++ + L Y Sbjct: 885 CTENYISSLEDESQILESKLAQVDQENESAKKEIEELRQQLESERRQKEADGKELSSTYQ 944 Query: 639 EVEDKLADISQLQSDQVCSEIKSVHLEE---QIDALSASKKELALVIENLKLDKEQLYGT 695 DKL +++++ SE+ + +E+ +++ ++S +++L E +QL Sbjct: 945 TELDKLKG----ENERLKSELDKLLVEKRDVEVNTRASSDAQVSLTEEERSQLLDQLSEK 1000 Query: 696 IKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELL---AKINHEEQSKIQTQFG 752 K++EN K I +K ++ Q + + L ++ + K +EL+ A ++ + + Sbjct: 1001 FKEIENLKATI-SKDKDSAQMARETVENLSQLISSKDNELIKLNATVDMFRNERDEVVKL 1059 Query: 753 IDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQL---GSYLQ-- 807 + K E Y I+ + L+++IA + SL+ K QL + LQ Sbjct: 1060 VQEKHNESLQYHAEIQRLTQLISDQTANLQKAIAEKDATLASLQEKESQLLWTQNELQVV 1119 Query: 808 -------EKQKAYSEYT-IQEDELVNR-LAVLMDHDRVVEKQLLEIEHENKELQKKNQIL 858 E+ + E I E L+++ ++ L + + +E +L+ + + LQ++ L Sbjct: 1120 KQRLQNIEESNNHGERCGIAEHTLLSKHVSTLEEKSKAMEAAILQDQSNIRYLQEQ---L 1176 Query: 859 LEENQNLQISLSDMQQHYNALVE-KANRTDLA-ESESTK--YQTQLRDLESNLKRITHEH 914 E I+L ++ + N LVE +AN T+ A +SE + Q +L E LK + + Sbjct: 1177 TEAQSKETIALKEVDRLRNHLVEMEANYTEEALQSEEIQRTLQARLMQAEEKLKNSSTMY 1236 Query: 915 QTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEY---VTQLEAQLQEYKNN- 970 + V+ +++E L+ + ++ + ++ +K + Y +T L+ L++++ + Sbjct: 1237 TSASVRANQQVETLQQQLALIVQQRDDLQNKISSAEDKVLSYSASLTNLQLVLEQFQRDK 1296 Query: 971 -------IENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDE 1023 E L + +++ K EL+ + ++ + ++ + ++L L++K E Sbjct: 1297 EKDIQAATEKLRVELQQSYKKQDELVSEITSLKEQLAE--AKECLRAASRLTEQLEKKSE 1354 Query: 1024 EIIALNQKIN 1033 I LNQ++N Sbjct: 1355 RIELLNQEVN 1364 Score = 79.0 bits (186), Expect = 1e-12 Identities = 158/808 (19%), Positives = 338/808 (41%), Gaps = 95/808 (11%) Query: 250 ISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLA--KQSIEPSCEEK 307 ++ L+E ++A +S E +L +L+ LA ++ ++ S EEK Sbjct: 620 LTILQETKNEVDADNEVLSREKEQLEADLKLLSSGSDLKKSDGDALAELREQLKKSKEEK 679 Query: 308 TEIEEKGSLEIANM-TELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKG 366 ++E +I NM EL + +E LE +I + +L+N+ +K+ Sbjct: 680 DDLE----YDIRNMRNELDQSLEQLEANRAEIEKL--QLDNERL------------AKEN 721 Query: 367 SPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLV---- 422 L+ + S + K L Q+ D NK+E+ K + + + ++ Sbjct: 722 GKLLDQFSETQKENLDKVDLLNTEMTLLQQELDG--NKDELEKTMRYLSDMEEKILTLKN 779 Query: 423 DKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQ 482 + E + E K+ L + L+H + +L + E V+ + Sbjct: 780 ENERLNVEASKIKENEIEFLKLKEQL-EERSLDHTKEELDAALKKLSELEEKVSMLESEN 838 Query: 483 EQLKQEL--NDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQM 540 ++L+ EL ++ N K L+E ++ +++I + N+E A +K N+ L+ Sbjct: 839 KRLQDELIRTSDVDSEN-KRLVEAIEEKQKEIAK-NEEEAANVTTKLKCTENYISSLEDE 896 Query: 541 QKTIDN-FSKVSDSN----KEIVRLTEELH-HLSQKVAELEEEKGNLQLHLVDYDS-GRM 593 + +++ ++V N KEI L ++L QK A+ +E Q L Sbjct: 897 SQILESKLAQVDQENESAKKEIEELRQQLESERRQKEADGKELSSTYQTELDKLKGENER 956 Query: 594 IESDVYKKMIEMENL-AETRLKA---ISLLESQKFDLVQELHILQQKYDEVEDKLADISQ 649 ++S++ K ++E ++ TR + +SL E ++ L+ +L +K+ E+E+ A IS+ Sbjct: 957 LKSELDKLLVEKRDVEVNTRASSDAQVSLTEEERSQLLDQL---SEKFKEIENLKATISK 1013 Query: 650 LQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNK 709 + + +L + I + +L ++ + +++++ +++ N+ + Sbjct: 1014 DKDSAQMARETVENLSQLISSKDNELIKLNATVDMFRNERDEVVKLVQEKHNESLQYHAE 1073 Query: 710 LQNYIQENMDLTDKLEKMSAEKISELLAKINHEE------QSKIQT------------QF 751 +Q Q D T L+K AEK LA + +E Q+++Q Sbjct: 1074 IQRLTQLISDQTANLQKAIAEK-DATLASLQEKESQLLWTQNELQVVKQRLQNIEESNNH 1132 Query: 752 GIDAKIQERDLYIENI----------ESELSKYKSRICRLEESIAVMEDRRYSLERKADQ 801 G I E L +++ E+ + + +S I L+E + + + ++ D+ Sbjct: 1133 GERCGIAEHTLLSKHVSTLEEKSKAMEAAILQDQSNIRYLQEQLTEAQSKETIALKEVDR 1192 Query: 802 LGSYLQEKQKAYSEYTIQEDELVNRL-AVLMDHDRVVEKQL-------LEIEHENKELQK 853 L ++L E + Y+E +Q +E+ L A LM + ++ + + + LQ+ Sbjct: 1193 LRNHLVEMEANYTEEALQSEEIQRTLQARLMQAEEKLKNSSTMYTSASVRANQQVETLQQ 1252 Query: 854 KNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHE 913 + +++++ +LQ +S + L A+ T+L + Q Q RD E +++ T + Sbjct: 1253 QLALIVQQRDDLQNKISSAED--KVLSYSASLTNL---QLVLEQFQ-RDKEKDIQAATEK 1306 Query: 914 HQTLIVQKKKEIEDLEIEFNT------QIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEY 967 + + Q K+ ++L E + + + +R L E+ EK E + L ++ Sbjct: 1307 LRVELQQSYKKQDELVSEITSLKEQLAEAKECLRAASRLTEQLEKKSERIELLNQEVNRL 1366 Query: 968 KNNIENLNMNVEELNKMNLELIDKHVQK 995 + + +EE K +D+ + K Sbjct: 1367 TELVNTADQRIEEAKKSGEGKVDRSLVK 1394 Score = 70.5 bits (165), Expect = 4e-10 Identities = 144/679 (21%), Positives = 300/679 (44%), Gaps = 77/679 (11%) Query: 233 KDEKQRLLKDIESKDVRISSLEEANKLL--EAARF-EISLEHSKLAQELEQXXXXXXXXX 289 KDE ++ ++ + + +I +L+ N+ L EA++ E +E KL ++LE+ Sbjct: 757 KDELEKTMRYLSDMEEKILTLKNENERLNVEASKIKENEIEFLKLKEQLEERSLDH---- 812 Query: 290 XXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENK- 348 K+ ++ + ++ +E+EEK +M E K L + L IR ++ + ENK Sbjct: 813 ------TKEELDAALKKLSELEEK-----VSMLESENK-RLQDEL---IRTSDVDSENKR 857 Query: 349 -LATMGTESKAVSSPSKKGSPLISR-KSGRNTASKMKSPWSQLSSETLNQDTDKKINKNE 406 + + + K ++ ++ + + ++ K N S ++ L S+ D + + K E Sbjct: 858 LVEAIEEKQKEIAKNEEEAANVTTKLKCTENYISSLEDESQILESKLAQVDQENESAKKE 917 Query: 407 IAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLI 466 I +L Q L + KE E + G++ +L+ E + + + Sbjct: 918 IEELR---QQLESERRQKEADGKELSSTYQTELDKLKGEN---ERLKSELDKLLVEKRDV 971 Query: 467 HVGTNTEDVNEIAKVQE---QLKQELNDEIKDV-NVKDLIEKLKSAEEQITQLNDEIDAA 522 V T +++ +E QL +L+++ K++ N+K I K K + + + + + Sbjct: 972 EVNTRASSDAQVSLTEEERSQLLDQLSEKFKEIENLKATISKDKDSAQMARETVENL--- 1028 Query: 523 NKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLS-------QKVAEL- 574 +I K N +KL T+D F D E+V+L +E H+ S Q++ +L Sbjct: 1029 -SQLISSKDNELIKL---NATVDMFRNERD---EVVKLVQEKHNESLQYHAEIQRLTQLI 1081 Query: 575 EEEKGNLQLHLVDYDSGRMIESDVYKKMIEMEN-LAETRLKAISLLESQKFDL---VQEL 630 ++ NLQ + + D+ + +++ +N L + + ++ ES + E Sbjct: 1082 SDQTANLQKAIAEKDATLASLQEKESQLLWTQNELQVVKQRLQNIEESNNHGERCGIAEH 1141 Query: 631 HILQQKYDEVEDK-LADISQLQSDQVCSEIKSVHLEEQIDALSASKKELAL-VIENLKLD 688 +L + +E+K A + + DQ S I+ +L+EQ+ + SK+ +AL ++ L+ Sbjct: 1142 TLLSKHVSTLEEKSKAMEAAILQDQ--SNIR--YLQEQLTE-AQSKETIALKEVDRLRNH 1196 Query: 689 KEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQ 748 ++ + E+I LQ + M +KL K S+ + + N + ++ +Q Sbjct: 1197 LVEMEANYTEEALQSEEIQRTLQARL---MQAEEKL-KNSSTMYTSASVRANQQVET-LQ 1251 Query: 749 TQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQ- 807 Q + +Q+RD I S K S L V+E + E+ L+ Sbjct: 1252 QQLAL--IVQQRDDLQNKISSAEDKVLSYSASLTNLQLVLEQFQRDKEKDIQAATEKLRV 1309 Query: 808 EKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQI 867 E Q++Y ++DELV+ + L + ++ L ++L+KK++ + NQ + Sbjct: 1310 ELQQSYK----KQDELVSEITSLKEQLAEAKECLRAASRLTEQLEKKSERIELLNQEVN- 1364 Query: 868 SLSDMQQHYNALVEKANRT 886 L+++ + +E+A ++ Sbjct: 1365 RLTELVNTADQRIEEAKKS 1383 Score = 65.3 bits (152), Expect = 1e-08 Identities = 175/883 (19%), Positives = 368/883 (41%), Gaps = 97/883 (10%) Query: 742 EEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQ 801 E QSK+ + ++ + + I ++ESEL++ ++ S V +D E A Q Sbjct: 89 ENQSKL-----LQDQLDQATVRIRDLESELNRVQTL-----NSSNVKDDANIK-EEGASQ 137 Query: 802 LGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEE 861 L+ KQ + IQ E V+ + R+ + +L + K + K E+ Sbjct: 138 KAELLRAKQDVMNRI-IQMGEKSRE--VVRNAKRLQQDELTLVGDFRKAISKLASP--EQ 192 Query: 862 NQNLQISLSDMQQHYNALVEKANRTDLA--ESESTKYQTQLRD-LESNLKRITHEHQTLI 918 ++ +L ++ L A +TD ++E + RD E+ L+R + + Sbjct: 193 YDLIRSALMALENESEQLQGSAEKTDSVGYDAEGKSRNEKGRDESEAKLRRRVEDLEAEN 252 Query: 919 VQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNV 978 + IE+L+ + IE + K+ L +K+ QL + + IENL Sbjct: 253 QSLSQSIEELDKQNAESIERVLSLKEELQKKHHSLQGAYEQLYVEYNQALGKIENLQQQQ 312 Query: 979 E--------ELNKM-NLELIDKHVQK-QQTQSPDYTEQYINEINKLNALLKQKDEEIIAL 1028 + EL+K N +D VQ Q + TE + +K + K+++ + + Sbjct: 313 QQQQQQQKPELSKAPNKSSLDTAVQTLAQLKLDKETEIRPAKEDKQTEISTSKEDKEVEV 372 Query: 1029 NQKINNAQ--VSYMSMVSDYESKLAQFTTKLENMEEEM-QRVSKQLLDSKQHNEELQILV 1085 + K + Q S + V+D K A E++ + + V++Q ++ K E L+ + Sbjct: 373 DLKPEDQQDLASELKKVNDI-LKNAPLEPSNEHLNDSVFVAVARQFVELKWKKETLERKL 431 Query: 1086 REQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQ 1145 EQ Q+KE +E + + +++ + I S +E + +N+ L+ Sbjct: 432 TEQSRQLKETQELRDSLQIDCEDMQTNIESLVME-VQHLKSNLPSIPEASEERVASLET- 489 Query: 1146 EEEEFIQERSVLQEQSAKLNTELQECYTKI--------IQLETLNTELTGHDVVNQEQIN 1197 E E E L++ A +++EL+ I ++L T L N+ + + Sbjct: 490 ETESLQAEILALRKSKADMSSELKAIKAAIREDGGGGGVELATRIESLLAEQ--NKSKSS 547 Query: 1198 QLKSKLEQLN-TENDNLLSTVAELRSSISSAVDQ-RGF-EIAELWKQHLAQREADFQKTE 1254 + ++L Q EN L + L S + ++++ +G E EL + + + D + Sbjct: 548 KDPAELLQATLDENTALRRRIDVLESELRVSLERCKGLDENIEL----IEELKLDLENAR 603 Query: 1255 HELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHL----RNLQ 1310 EL++ LS + L++ + QE N++ +V S + + + + L +L+ Sbjct: 604 RELKIALS-----NNKRLENSLTILQETKNEVDADNEVLSREKEQLEADLKLLSSGSDLK 658 Query: 1311 EKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNI 1370 + D + ++ + ++EK DL + ++ + +QS+ + Sbjct: 659 KSDGDALAELREQLKKSKEEK------------------DDLEYDIRNMRNELDQSLEQL 700 Query: 1371 NEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQR 1430 A+++K ++ E +++L ++E+ E L Sbjct: 701 EANRAEIEKLQLDNERLAKENGKLLDQFSETQKENLDKVDLLNTEMTLLQQE----LDGN 756 Query: 1431 NDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERV-KLIE 1489 DE E + L + E++I L E E L + K+ EN + ++++ E + E Sbjct: 757 KDELEKTMRYLSDMEEKILTLKNENE-RLNVEASKIKENEIEFLKLKEQLEERSLDHTKE 815 Query: 1490 ELNVKITESVSLNKQVAEL---NKALEEEVAKTNEMQT-------ALENQEIEIVTLNDE 1539 EL+ + + L ++V+ L NK L++E+ +T+++ + A+E ++ EI +E Sbjct: 816 ELDAALKKLSELEEKVSMLESENKRLQDELIRTSDVDSENKRLVEAIEEKQKEIAKNEEE 875 Query: 1540 ITNLQNMVRASSSKIQ--KHVSFASDTKQGRDEQLDNTMNKEL 1580 N+ ++ + + I + S ++K + +Q + + KE+ Sbjct: 876 AANVTTKLKCTENYISSLEDESQILESKLAQVDQENESAKKEI 918 Score = 54.0 bits (124), Expect = 3e-05 Identities = 129/676 (19%), Positives = 282/676 (41%), Gaps = 67/676 (9%) Query: 141 LGDVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXX 200 L D+ T+K ++ L+V K+K E L L+E++ E+ + K + Sbjct: 767 LSDMEEKILTLKNENERLNVEASKIKENEIEFLKLKEQLEER-SLDHTKEELDAALKKLS 825 Query: 201 XXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLL 260 E+ ++Q+ I ++ E +RL++ IE K I+ EE + Sbjct: 826 ELEEKVSMLESEN-----KRLQDELI-RTSDVDSENKRLVEAIEEKQKEIAKNEEEAANV 879 Query: 261 EAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIAN 320 + + + + ++ Q AK+ IE E + ++E + + A+ Sbjct: 880 -TTKLKCTENYISSLEDESQILESKLAQVDQENESAKKEIE---ELRQQLESERRQKEAD 935 Query: 321 MTELTKKIEL-LEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTA 379 EL+ + L+ L + + EL+ KL + + + S ++ + Sbjct: 936 GKELSSTYQTELDKLKGENERLKSELD-KLLVEKRDVEVNTRASSDAQVSLTEEERSQLL 994 Query: 380 SKMKSPWSQLSS--ETLNQDTDK-KINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXX 436 ++ + ++ + T+++D D ++ + + L +I S + +L+ + Sbjct: 995 DQLSEKFKEIENLKATISKDKDSAQMARETVENLSQLISSKDNELIKLNATVD------- 1047 Query: 437 XXXXXXXGKDTLIAQLQLEH----QQHMEGPSLIH-VGTNTEDVNE-IAKVQEQLKQELN 490 +D ++ +Q +H Q H E L + T ++ + IA+ L Sbjct: 1048 ---MFRNERDEVVKLVQEKHNESLQYHAEIQRLTQLISDQTANLQKAIAEKDATLASLQE 1104 Query: 491 DEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKV 550 E + + ++ ++ +K + I + N+ + + S H L++ K ++ + + Sbjct: 1105 KESQLLWTQNELQVVKQRLQNIEESNNHGERCGIAEHTLLSKHVSTLEEKSKAME--AAI 1162 Query: 551 SDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSG---RMIESDVYKKMIEMEN 607 I L E+L K +E L+ HLV+ ++ ++S+ ++ ++ Sbjct: 1163 LQDQSNIRYLQEQLTEAQSKETIALKEVDRLRNHLVEMEANYTEEALQSEEIQRTLQARL 1222 Query: 608 L-AETRLK-AISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLE 665 + AE +LK + ++ S Q++ LQQ +LA I Q Q D + ++I S E Sbjct: 1223 MQAEEKLKNSSTMYTSASVRANQQVETLQQ-------QLALIVQ-QRDDLQNKISSA--E 1272 Query: 666 EQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLE 725 +++ + SAS L LV+E + DKE KD++ E + +LQ ++ +L ++ Sbjct: 1273 DKVLSYSASLTNLQLVLEQFQRDKE------KDIQAATEKLRVELQQSYKKQDELVSEIT 1326 Query: 726 KMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESI 785 + E+++E AK S++ Q ++++ IE + E+++ + ++ I Sbjct: 1327 SLK-EQLAE--AKECLRAASRLTEQ------LEKKSERIELLNQEVNRLTELVNTADQRI 1377 Query: 786 AVMEDRRYSLERKADQ 801 E+ + S E K D+ Sbjct: 1378 ---EEAKKSGEGKVDR 1390 >UniRef50_Q4S7F6 Cluster: Chromosome 13 SCAF14715, whole genome shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 13 SCAF14715, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1396 Score = 122 bits (294), Expect = 8e-26 Identities = 249/1268 (19%), Positives = 530/1268 (41%), Gaps = 134/1268 (10%) Query: 303 SCEEKTEIEE-KGSL-EIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVS 360 S E K E+++ +G L ++ L +K+ E I+Q E K A + TE + Sbjct: 63 SGELKKELDKVQGHLKQVIPFRSLERKLNEAETEKFNIKQMKDLFEQKAAQLATEIVDLK 122 Query: 361 SPSKKGSPLISRKSGR-----NTASKMKSPWSQLSSETLNQD--TDKKINKNEIAKLEMV 413 S + L + + K +L +E L + D ++ + E+ +++ + Sbjct: 123 SRYDEEKSLRDAADHKLANLNEQLQREKQEKERLLTELLQRPGVEDVEVLQKELVQVQTL 182 Query: 414 IQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNT- 472 + S+ ++ +E + IAQL+ E ++ GP + V T Sbjct: 183 MDSMTRE---REEESERLKNHYEQLQANYTNSEMTIAQLKAELEK---GPQEVAVYTKEI 236 Query: 473 ----EDVNEIAKVQEQLKQELNDEIKD-VNVKDLIEKLKSAEEQITQLNDEIDAANKNMI 527 +N + + + L ++L + KD + +++++ K K ++++ E D + + Sbjct: 237 HELRSSLNSLQQQSQSLSEKLEQKEKDYLQLEEMLAKEKGSKKKAQDGLKERDQEVQELQ 296 Query: 528 KVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNL-QLHLV 586 + + L++ Q +++ + +E+ +L E+ L K AEL+ E+ L QL Sbjct: 297 ARLAGAETSLQKAQ------AELQERTEEVSKLRSEMGELEVKHAELKVERKQLEQLREE 350 Query: 587 DYDSGRMIESDV---YKKMIEMENL---AETRLKAISLLESQKF-DLVQELHILQQKYDE 639 G ++++ + K++E E E RLK L +K D Q+ LQ K Sbjct: 351 KESHGAQQQTEIGQLHAKLLETERQLGEVEGRLKEQRQLSGEKLKDREQQAADLQLKLSR 410 Query: 640 VEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDL 699 E++L + S K+ L+ Q++ +EL ++ +N G +++ Sbjct: 411 TEEQLKE----------SATKNTDLQHQLEKAKQQHQELQVLQQNTN-------GKLREA 453 Query: 700 ENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQE 759 +ND E ++ ++ + Q+ +L L+K S + +S+L A+ + +KIQ G A + + Sbjct: 454 QNDLEQVLRQIGDKDQKIQNLEALLQK-SKDIVSQLEAE-RDDLCAKIQAGEGETAVLNQ 511 Query: 760 RDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEK----QKAYSE 815 + ++ ++++ ++ ES +D + ++ L Q++ + +E Sbjct: 512 LKDKNQALQGQVTQLTDKLKNQSESNKQAQDNLHKQVQEQKTLLRSAQDRAHTMETTVTE 571 Query: 816 YTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQH 875 T Q + +++ L + + LL E K QK N + + Q +L D QQ Sbjct: 572 LTAQLTDSKEKVSQLDAQLKAKTEMLLSAEAA-KAAQKAN--MENSLETAQHALQDKQQE 628 Query: 876 YNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQ 935 N + +K + E + TQL E+N+K E++ ++ ++ E L+ N + Sbjct: 629 LNKVQKKIEEQTQSLKEKREQCTQL---ETNVK----EYKDKLLASEQRTEQLQ-SLNKR 680 Query: 936 IESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQK 995 +ES + + + +E+ ++ ++ + + ++++ +++ ++ E+ K+ L D +QK Sbjct: 681 LESQLGELQTAHEQVQQQVQKLQKESTEMKQKAKELQH-SLETEKAGKLQNLLAD--LQK 737 Query: 996 QQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTT 1055 Q + E + EI L L + + AL + N V D E K Q + Sbjct: 738 AQQEK----EAHKKEIGSLQENLGKTKK---ALKESQN---------VLDAERKSHQ--S 779 Query: 1056 KLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIIS 1115 +E ++ Q+ ++LL + NE L + E DQ+++++E + + ++ + E + Sbjct: 780 AVEERDKSNQKARQELL---KKNEALTKTMNESKDQLEQMREAEKSLKVQLTSVEQQQVK 836 Query: 1116 STIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKI 1175 + E + N ++ L+V E ++ + + LQE K E ++ ++ Sbjct: 837 AQ-EALKQKQNQLEKLQAQLQTVEGSLEV-ETKKLKGQIAELQESGVKKAKEEKQLRAQV 894 Query: 1176 IQL-ETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFE 1234 L E L +E V Q+ + Q + +L ++ + V+ L + + ++ Sbjct: 895 AGLSEELASEKRRTTEV-QKALEQSQESQSKLQSDLYGKETEVSALHQDLRACEEKLKLA 953 Query: 1235 IAELW--KQHLAQREADFQKTE---HELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTM 1289 EL + H EA Q+ + L +L E K +Q +++ S + +T + Sbjct: 954 QEELAGNQTHQTGLEAQIQELQVSRGSLEEELGKLEHKLQQREQTLKDSEKHQTQVKEEL 1013 Query: 1290 EQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSE----IEDEKVAFXXXXXXXXXXX 1345 ++ S +L + L N + A + ++ + +++ K+ Sbjct: 1014 KREKSKAEELNKLKNDLENNSSRLAADLKALKEKSDKELGNLQEAKLLLIQQKLELQTQV 1073 Query: 1346 XXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLEL 1405 DL E + ++ ++ S+ + AQ+K + + +AK E Sbjct: 1074 EAAQGDLEQERKEHQSTKDGSLRRKEQLLAQIKDVQDQLSSEK-----KAREEQAKRGE- 1127 Query: 1406 THQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLK 1465 + E + S +E TL + E++ ++++ E EK+ +DL E+A+L Sbjct: 1128 --EAEARTSAQVTALNENVATLKR---EWQGSQRRVGELEKQTDDL----RGEIAVLEAT 1178 Query: 1466 MHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTA 1525 + N + ER L+E E L +V EL + LE+ A E+ Sbjct: 1179 VQNNQD-----------ERRALLERCVKGEGEIEKLQAKVVELRRKLEDTTAAMQEL--G 1225 Query: 1526 LENQEIEI 1533 ENQ ++I Sbjct: 1226 RENQSLQI 1233 Score = 118 bits (284), Expect = 1e-24 Identities = 186/907 (20%), Positives = 373/907 (41%), Gaps = 87/907 (9%) Query: 715 QENMDLTDKL--EKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELS 772 QE DL L E+ + ++ + L K+ + I + ++ K+ E + NI+ Sbjct: 47 QEVQDLHASLKEERWFSGELKKELDKVQGHLKQVIPFR-SLERKLNEAETEKFNIKQMKD 105 Query: 773 KYKSRICRLEESIAVME---DRRYSLERKAD-QLGSYLQEKQKAYSEYTIQEDELVNRLA 828 ++ + +L I ++ D SL AD +L + ++ Q+ E EL+ R Sbjct: 106 LFEQKAAQLATEIVDLKSRYDEEKSLRDAADHKLANLNEQLQREKQEKERLLTELLQRPG 165 Query: 829 VLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYN----ALVEKAN 884 V + V++K+L++++ + ++ + EE++ L+ +Q +Y + + Sbjct: 166 V--EDVEVLQKELVQVQTLMDSMTRERE---EESERLKNHYEQLQANYTNSEMTIAQLKA 220 Query: 885 RTDLAESESTKYQTQLRDLESNLKRITHEHQTL---IVQKKKEIEDLEIEFNTQIESAIR 941 + E Y ++ +L S+L + + Q+L + QK+K+ LE + S + Sbjct: 221 ELEKGPQEVAVYTKEIHELRSSLNSLQQQSQSLSEKLEQKEKDYLQLEEMLAKEKGSKKK 280 Query: 942 DKKVLNEKYEKNIEYVTQL----------EAQLQEYKNNIENLNMNVEELNKMNLEL-ID 990 + L E+ ++ E +L +A+LQE + L + EL + EL ++ Sbjct: 281 AQDGLKERDQEVQELQARLAGAETSLQKAQAELQERTEEVSKLRSEMGELEVKHAELKVE 340 Query: 991 -KHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESK 1049 K +++ + + + Q EI +L+A L + + ++ + ++ + + D E + Sbjct: 341 RKQLEQLREEKESHGAQQQTEIGQLHAKLLETERQLGEVEGRLKEQRQLSGEKLKDREQQ 400 Query: 1050 LAQFTTKLENMEEEMQR-------VSKQLLDSKQHNEELQIL-------VREQDDQIKEL 1095 A KL EE+++ + QL +KQ ++ELQ+L +RE + ++++ Sbjct: 401 AADLQLKLSRTEEQLKESATKNTDLQHQLEKAKQQHQELQVLQQNTNGKLREAQNDLEQV 460 Query: 1096 KETKLTFEMNIPKTEGMI-----ISSTIEPMSDDA--------------NNVDXXXXXXX 1136 + I E ++ I S +E DD N + Sbjct: 461 LRQIGDKDQKIQNLEALLQKSKDIVSQLEAERDDLCAKIQAGEGETAVLNQLKDKNQALQ 520 Query: 1137 XXXXXL--KVQEEEEFI-QERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQ 1193 L K++ + E Q + L +Q + T L+ + +ET TELT ++ Sbjct: 521 GQVTQLTDKLKNQSESNKQAQDNLHKQVQEQKTLLRSAQDRAHTMETTVTELTAQLTDSK 580 Query: 1194 EQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKT 1253 E+++QL + QL + + LLS AE + A + E A+ L ++ + K Sbjct: 581 EKVSQLDA---QLKAKTEMLLS--AEAAKAAQKANMENSLETAQ---HALQDKQQELNKV 632 Query: 1254 EHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTS-LQNKLQDKEEHLRNLQEK 1312 + ++ Q + + K EQ ++++ +E +K++ EQ T LQ+ + E L LQ Sbjct: 633 QKKIEEQTQSLKEKREQCTQ-LETNVKEYKDKLLASEQRTEQLQSLNKRLESQLGELQTA 691 Query: 1313 YADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINE 1372 + V Q++ L+ E + K +L + Q +Q +E I Sbjct: 692 HEQVQQQVQKLQKESTEMKQKAKELQHSLETEKAGKLQNLLADLQKAQQEKEAHKKEIGS 751 Query: 1373 ENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRND 1432 L K+ ++ V E + E+ +K T T+ + D Sbjct: 752 LQENLGKTKKALKESQNVLDAERKSHQSAVEERDKSNQKARQELLKKNEALTKTMNESKD 811 Query: 1433 EFENVRQ-------QLVEYEK---RIEDLTYEKESELAILRLKMHENANHYETMQKESEI 1482 + E +R+ QL E+ + ++ +K+++L L+ ++ E K+ + Sbjct: 812 QLEQMREAEKSLKVQLTSVEQQQVKAQEALKQKQNQLEKLQAQLQTVEGSLEVETKKLKG 871 Query: 1483 ERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITN 1542 + +L E K E L QVA L++ L E +T E+Q ALE + L ++ Sbjct: 872 QIAELQESGVKKAKEEKQLRAQVAGLSEELASEKRRTTEVQKALEQSQESQSKLQSDLYG 931 Query: 1543 LQNMVRA 1549 + V A Sbjct: 932 KETEVSA 938 Score = 111 bits (266), Expect = 2e-22 Identities = 214/1107 (19%), Positives = 452/1107 (40%), Gaps = 104/1107 (9%) Query: 510 EQITQLNDEIDAANKNMIKVK---SNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHH 566 E +T L E+ + ++ + + K +L ++Q + +++ E + Sbjct: 40 EDLTMLRQEVQDLHASLKEERWFSGELKKELDKVQGHLKQVIPFRSLERKLNEAETEKFN 99 Query: 567 LSQKVAELEEEKGNLQLHLVD----YDSGRMIESDVYKKMIEM-ENLA-ETRLKAISLLE 620 + Q E++ L +VD YD + + K+ + E L E + K L E Sbjct: 100 IKQMKDLFEQKAAQLATEIVDLKSRYDEEKSLRDAADHKLANLNEQLQREKQEKERLLTE 159 Query: 621 SQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELAL 680 + V+++ +LQ++ +V+ + +++ + ++ S L+ + L A+ + Sbjct: 160 LLQRPGVEDVEVLQKELVQVQTLMDSMTREREEE------SERLKNHYEQLQANYTNSEM 213 Query: 681 VIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAE--KISELLAK 738 I LK + E+ + + ++ + L + Q++ L++KLE+ + ++ E+LAK Sbjct: 214 TIAQLKAELEKGPQEVAVYTKEIHELRSSLNSLQQQSQSLSEKLEQKEKDYLQLEEMLAK 273 Query: 739 INHEEQSKIQTQFGI---DAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSL 795 E+ SK + Q G+ D ++QE + E+ L K ++ + E ++ + L Sbjct: 274 ---EKGSKKKAQDGLKERDQEVQELQARLAGAETSLQKAQAELQERTEEVSKLRSEMGEL 330 Query: 796 ERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKN 855 E K +L ++ KQ E +E E + A + +LLE E + E++ + Sbjct: 331 EVKHAELK--VERKQL---EQLREEKE--SHGAQQQTEIGQLHAKLLETERQLGEVEGR- 382 Query: 856 QILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQ 915 L E+ Q L D +Q L K +RT+ ES T DL+ L++ +HQ Sbjct: 383 --LKEQRQLSGEKLKDREQQAADLQLKLSRTEEQLKESATKNT---DLQHQLEKAKQQHQ 437 Query: 916 TLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLN 975 L V ++ L E +E +R + +K +K + LEA LQ+ K+ + L Sbjct: 438 ELQVLQQNTNGKLR-EAQNDLEQVLRQ---IGDKDQK----IQNLEALLQKSKDIVSQLE 489 Query: 976 MNVEEL-NKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINN 1034 ++L K+ + V Q D + ++ +L LK + E N++ Sbjct: 490 AERDDLCAKIQAGEGETAVLNQLK---DKNQALQGQVTQLTDKLKNQSES----NKQ--- 539 Query: 1035 AQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKE 1094 AQ + V + ++ L + ME + ++ QL DSK+ +L ++ + + + Sbjct: 540 AQDNLHKQVQEQKTLLRSAQDRAHTMETTVTELTAQLTDSKEKVSQLDAQLKAKTEMLLS 599 Query: 1095 LKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQER 1154 + K + N+ + ++ + N V K++E+ + ++E+ Sbjct: 600 AEAAKAAQKANMENSLETA-QHALQDKQQELNKVQK------------KIEEQTQSLKEK 646 Query: 1155 SVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLL 1214 +EQ +L T ++E K++ E +L + + Q+ +L++ EQ+ + L Sbjct: 647 ---REQCTQLETNVKEYKDKLLASEQRTEQLQSLNKRLESQLGELQTAHEQVQQQVQKLQ 703 Query: 1215 STVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDS 1274 E++ Q E + K L AD QK + E S E L Sbjct: 704 KESTEMKQKAKEL--QHSLETEKAGK--LQNLLADLQKAQQEKEAHKKEIGSLQENL--G 757 Query: 1275 VQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAF 1334 +E+ ++ E+ S Q+ +++++ ++ Q+ +++ + E L + + K Sbjct: 758 KTKKALKESQNVLDAER-KSHQSAVEERD---KSNQKARQELLKKNEALTKTMNESK--- 810 Query: 1335 XXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXR 1394 L+ + S +Q Q ++ + ++ QL+K Sbjct: 811 -----DQLEQMREAEKSLKVQLTSVEQQQVKAQEALKQKQNQLEKLQAQLQTVEGSLEVE 865 Query: 1395 VNDAEAKVLELTHQLELKDSEIYQKT------HEYTITLTQRNDEFENVRQQLVEYEKRI 1448 + ++ EL K E Q E + +R E + +Q E + ++ Sbjct: 866 TKKLKGQIAELQESGVKKAKEEKQLRAQVAGLSEELASEKRRTTEVQKALEQSQESQSKL 925 Query: 1449 EDLTYEKESELAILRLKMHENANHYETMQKE---SEIERVKLIEELNVKITESVSLNKQV 1505 + Y KE+E++ L + + Q+E ++ + L ++ SL +++ Sbjct: 926 QSDLYGKETEVSALHQDLRACEEKLKLAQEELAGNQTHQTGLEAQIQELQVSRGSLEEEL 985 Query: 1506 AELNKALE--EEVAKTNEM-QTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFAS 1562 +L L+ E+ K +E QT ++ + + +E+ L+N + +SS++ + Sbjct: 986 GKLEHKLQQREQTLKDSEKHQTQVKEELKREKSKAEELNKLKNDLENNSSRLAADL---K 1042 Query: 1563 DTKQGRDEQLDNTMNKELLDAVPRAEL 1589 K+ D++L N +LL + EL Sbjct: 1043 ALKEKSDKELGNLQEAKLLLIQQKLEL 1069 Score = 93.1 bits (221), Expect = 6e-17 Identities = 203/1107 (18%), Positives = 444/1107 (40%), Gaps = 80/1107 (7%) Query: 51 QIKFERAQKCLENAALVSKRIKEHRKATAELLGRPFVPGISESLANTLKQKE---ILMEK 107 Q+K E +K + A+ +K I E R + L + S+SL+ L+QKE + +E+ Sbjct: 217 QLKAE-LEKGPQEVAVYTKEIHELRSSLNSLQQQ------SQSLSEKLEQKEKDYLQLEE 269 Query: 108 IKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNALSVLQVKMKI 167 + ++ SK+ + ++ + ++E+ +S L+ +M Sbjct: 270 MLAKEKGSKKKAQDGLKERDQEVQELQARLAGAETSLQKAQAELQERTEEVSKLRSEMGE 329 Query: 168 METTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIA 227 +E +L+ + + +Q+ E K + +++E Sbjct: 330 LEVKHAELKVERKQLEQLREEKESHGAQQQTEIGQLHAKLLETERQLGEVEGRLKEQRQL 389 Query: 228 MEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHS-KLAQELEQXXXXXX 286 + KD +Q+ D++ K +S EE +L E+A L+H + A++ Q Sbjct: 390 SGEKLKDREQQAA-DLQLK---LSRTEE--QLKESATKNTDLQHQLEKAKQQHQELQVLQ 443 Query: 287 XXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELE 346 A+ +E + + ++K I N+ L +K + + Q+ +L Sbjct: 444 QNTNGKLREAQNDLEQVLRQIGDKDQK----IQNLEALLQKSK---DIVSQLEAERDDLC 496 Query: 347 NKLATMGTESKAVSSPSKKGSPLISRKSG-----RNTASKMKSPWSQLSSETLNQDTDKK 401 K+ E+ ++ K L + + +N + K L + Q T + Sbjct: 497 AKIQAGEGETAVLNQLKDKNQALQGQVTQLTDKLKNQSESNKQAQDNLHKQVQEQKTLLR 556 Query: 402 INKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHME 461 ++ +E + L L D + +S+ D + A + + +E Sbjct: 557 SAQDRAHTMETTVTELTAQLTDSKEKVSQLDAQLKAKTEMLLSAEAAKAAQKANMENSLE 616 Query: 462 GPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIK-----DVNVKDLIEKLKSAEEQITQLN 516 + +++N++ K E+ Q L ++ + + NVK+ +KL ++E++ QL Sbjct: 617 TAQHA-LQDKQQELNKVQKKIEEQTQSLKEKREQCTQLETNVKEYKDKLLASEQRTEQLQ 675 Query: 517 DEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRL--TEELHHLSQKVAEL 574 + ++++ H+ +Q+QK +++ KE+ TE+ L +A+L Sbjct: 676 SLNKRLESQLGELQTAHEQVQQQVQKLQKESTEMKQKAKELQHSLETEKAGKLQNLLADL 735 Query: 575 EEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQ 634 ++ + + H + S + K + E +N+ + K+ ++ Q+ Sbjct: 736 QKAQQEKEAHKKEIGSLQENLGKTKKALKESQNVLDAERKSHQSAVEERDKSNQKARQEL 795 Query: 635 QKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYG 694 K +E K + S+ Q +Q+ KS L+ Q+ ++ + + ++ + E+L Sbjct: 796 LKKNEALTKTMNESKDQLEQMREAEKS--LKVQLTSVEQQQVKAQEALKQKQNQLEKLQA 853 Query: 695 TIKDLENDKEDIMNKLQNYI---QENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQF 751 ++ +E E KL+ I QE+ K EK +++ L ++ E++ + Q Sbjct: 854 QLQTVEGSLEVETKKLKGQIAELQESGVKKAKEEKQLRAQVAGLSEELASEKRRTTEVQK 913 Query: 752 GID------AKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSY 805 ++ +K+Q DLY + E+E+S + EE + + ++ + L + Sbjct: 914 ALEQSQESQSKLQS-DLYGK--ETEVSALHQDLRACEEKLKLAQEELAGNQTHQTGLEAQ 970 Query: 806 LQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNL 865 +QE Q + + +L ++L + EK +++ E K + K + L + +L Sbjct: 971 IQELQVSRGSLEEELGKLEHKLQQREQTLKDSEKHQTQVKEELKREKSKAEELNKLKNDL 1030 Query: 866 QISLSDMQQHYNALVEKANRT--DLAES------ESTKYQTQLRDLESNLKRITHEHQTL 917 + + S + AL EK+++ +L E+ + + QTQ+ + +L++ EHQ+ Sbjct: 1031 ENNSSRLAADLKALKEKSDKELGNLQEAKLLLIQQKLELQTQVEAAQGDLEQERKEHQST 1090 Query: 918 IVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMN 977 + E L + + +KK E+ ++ E + AQ+ N+ L Sbjct: 1091 KDGSLRRKEQLLAQIKDVQDQLSSEKKAREEQAKRGEEAEARTSAQVTALNENVATLKRE 1150 Query: 978 VEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQV 1037 + + EL +KQ T+ EI L A ++ +E AL ++ V Sbjct: 1151 WQGSQRRVGEL-----EKQ-------TDDLRGEIAVLEATVQNNQDERRALLERC----V 1194 Query: 1038 SYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVRE--QDDQIKEL 1095 + ++K+ + KLE+ MQ + ++ + ++ Q L R+ +D +++ Sbjct: 1195 KGEGEIEKLQAKVVELRRKLEDTTAAMQELGRE--NQSLQIKQSQSLTRKWAEDHEVQSC 1252 Query: 1096 KETKLTFEMNIPKTEGMIISSTIEPMS 1122 F + + K G S + P+S Sbjct: 1253 MGCGKGFSVTVRKVGG-APKSPLSPIS 1278 >UniRef50_Q115P0 Cluster: Chromosome segregation ATPase-like protein; n=1; Trichodesmium erythraeum IMS101|Rep: Chromosome segregation ATPase-like protein - Trichodesmium erythraeum (strain IMS101) Length = 1209 Score = 122 bits (294), Expect = 8e-26 Identities = 177/827 (21%), Positives = 358/827 (43%), Gaps = 65/827 (7%) Query: 327 KIELLEHLNCQIRQTNKELENKLATM-GTESKAVSSPSKKGSPLISRKSGRNTASKMKSP 385 ++EL E + Q+ Q ELE + + GTE+K S + + + + +++KS Sbjct: 305 QLELTE-VKSQLIQIQDELEKYITQLDGTEAKLSESQQQLHNKEKVYEKSQLELTEVKSQ 363 Query: 386 WSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGK 445 ++ + + ++N E E Q NK+ V ++ + E Sbjct: 364 LTKTQDDL--EKYVSQLNGTEAKLSESQQQLHNKEKVYEKSQL-ELTEVKSQLTKTQDDL 420 Query: 446 DTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKL 505 + ++QL + E +H N E V E K Q++ ++ + K K+ +L Sbjct: 421 EKYVSQLNGTEAKLSESQQQLH---NKEKVLE--KTQDEFQKVQQIQTKFDQTKN---EL 472 Query: 506 KSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTI-DNFSKVSDSNKEIVRLTEEL 564 +A+ Q+ + E+ + K K K + QK + + SK+ ++ E+V+ +L Sbjct: 473 ATAKSQLNETKTELIQCQSEL-KEKEGELQKYQGTQKELLETQSKLDETQGELVQYQSQL 531 Query: 565 HHLSQKVAELEEEKGNLQ-LHLVDYDSGRMIESDVYK----KMIEMENLAETRLKAISLL 619 H Q + ELE+ LQ L + +E++ K + +N AE SL Sbjct: 532 H---QNLEELEKNICKLQEAELAWKELKFQLETNEELLDKFKFQDKQNQAELGQTKHSLY 588 Query: 620 ESQ-KFDLVQ-ELHILQQKYDEVEDKL-ADISQLQSDQVCSEIKSVHLEEQIDALSASKK 676 E++ K Q +LH Q+ ++ + +L A L+ Q + LE+ L ++ Sbjct: 589 ETKIKLKTSQNQLHKTQEFWESSQSQLVAKEVVLKKYQQDLQDAEKALEDTYSQLQRTQI 648 Query: 677 ELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELL 736 EL + +NL K +L+ L +E+ K Q+ + L ++ + + Sbjct: 649 ELGVTRQNLSESKGELFIYKYQLHQSQEE-WEKYQSQLAGTEVLLEEYHSQLKQATEQ-- 705 Query: 737 AKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLE 796 + QSK+ +A +Q ++ + SEL K K LE S + ++ +E Sbjct: 706 ---KQQTQSKLTET---EAILQAKEAELTESNSELEKIK---LELERSGSDLQKTHQEVE 756 Query: 797 RKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQ 856 + QL ++KQ+ S+ T E L + A L + + +EK LE+E +LQK +Q Sbjct: 757 KNQSQLKQAEEQKQQTQSKLTETEAILQAKEAELTESNSELEKIKLELERSGSDLQKTHQ 816 Query: 857 ILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQ----------TQLRDLESN 906 L + L + +D+ + + L +K R + +E+E + Q ++L + Sbjct: 817 ELQQIQSQLNQTQADLTESNSQLKDKETRWEKSEAELKEIQKSQNKWEISKSELHKTKQE 876 Query: 907 LKRITHEHQTL---IVQKKKEIEDLE---IEFNTQIESAIRDKKVLNEKYEKNIEYVTQL 960 LKR ++Q L +V+ +++ + +E N+Q++ + N + ++ + + Sbjct: 877 LKRSQLQNQELQIELVESNSQLQQTKTELVESNSQLQQTKTELVESNSQLQQTKTELVES 936 Query: 961 EAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQT-----QSPDYTEQYINEINKLN 1015 +QLQ+ K + N +L + EL++ + Q QQT +S +Q E+ + N Sbjct: 937 NSQLQQTKTELVESN---SQLQQTKTELVESNSQLQQTKTELVESNSQLQQTKTELVESN 993 Query: 1016 ALLKQKDEEIIALNQKINNAQVSYM---SMVSDYESKLAQFTTKLENMEEEMQRVSKQLL 1072 + L+Q E++ N ++ + S +S L +F T+L +EE + + QL Sbjct: 994 SQLQQTKTELVESNSQLQQTETLLQKSNSQSQQTKSLLIEFKTQLHQTDEERENMQIQLQ 1053 Query: 1073 DSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIE 1119 +++ +E+Q R+ + +++ + + + + T+ +I + E Sbjct: 1054 ETQAVLQEIQTQWRKTEILLQQSQSQQQNVQKELVGTKSQLIETKSE 1100 Score = 108 bits (259), Expect = 1e-21 Identities = 176/886 (19%), Positives = 376/886 (42%), Gaps = 68/886 (7%) Query: 477 EIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKL- 535 E+ +V+ QL Q + DE++ I +L E ++++ ++ NK + KS +L Sbjct: 307 ELTEVKSQLIQ-IQDELEKY-----ITQLDGTEAKLSESQQQLH--NKEKVYEKSQLELT 358 Query: 536 KLK-QMQKTIDNFSK-VSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRM 593 ++K Q+ KT D+ K VS N +L+E L K E+ QL L + S Sbjct: 359 EVKSQLTKTQDDLEKYVSQLNGTEAKLSESQQQLHNKEKVYEKS----QLELTEVKSQLT 414 Query: 594 IESDVYKKMIEMENLAETRLKAIS--LLESQKF-----DLVQELHILQQKYDEVEDKLA- 645 D +K + N E +L L +K D Q++ +Q K+D+ +++LA Sbjct: 415 KTQDDLEKYVSQLNGTEAKLSESQQQLHNKEKVLEKTQDEFQKVQQIQTKFDQTKNELAT 474 Query: 646 ---DISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLEND 702 +++ +++ + + + E ++ ++KEL + KLD+ Q G + ++ Sbjct: 475 AKSQLNETKTELIQCQSELKEKEGELQKYQGTQKEL--LETQSKLDETQ--GELVQYQSQ 530 Query: 703 KEDIMNKLQNYI--QENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFG-IDAKIQE 759 + +L+ I + +L K K E ELL K +++ Q + G + E Sbjct: 531 LHQNLEELEKNICKLQEAELAWKELKFQLETNEELLDKFKFQDKQN-QAELGQTKHSLYE 589 Query: 760 RDLYIENIESELSK----YKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSE 815 + ++ +++L K ++S +L V++ + L+ L + Q+ E Sbjct: 590 TKIKLKTSQNQLHKTQEFWESSQSQLVAKEVVLKKYQQDLQDAEKALEDTYSQLQRTQIE 649 Query: 816 YTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQH 875 + L L + + + E E +L +L E + L+ + QQ Sbjct: 650 LGVTRQNLSESKGELFIYKYQLHQSQEEWEKYQSQLAGTEVLLEEYHSQLKQATEQKQQT 709 Query: 876 YNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFN-T 934 + L E E+E T+ ++L ++ L+R + +QK + E+E N + Sbjct: 710 QSKLTETEAILQAKEAELTESNSELEKIKLELERSGSD-----LQKTHQ----EVEKNQS 760 Query: 935 QIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVE----ELNKMNLELID 990 Q++ A K+ K + + EA+L E + +E + + +E +L K + EL Sbjct: 761 QLKQAEEQKQQTQSKLTETEAILQAKEAELTESNSELEKIKLELERSGSDLQKTHQELQQ 820 Query: 991 KHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYE--- 1047 Q QTQ+ D TE +++ ++ + E+ + + N ++S + + Sbjct: 821 IQSQLNQTQA-DLTESN-SQLKDKETRWEKSEAELKEIQKSQNKWEISKSELHKTKQELK 878 Query: 1048 -SKLAQFTTKLENMEE--EMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEM 1104 S+L ++E +E ++Q+ +L++S ++ + + E + Q+++ K + Sbjct: 879 RSQLQNQELQIELVESNSQLQQTKTELVESNSQLQQTKTELVESNSQLQQTKTELVESNS 938 Query: 1105 NIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKL 1164 + +T+ ++ S + V+ V+ + Q ++ L E +++L Sbjct: 939 QLQQTKTELVESNSQLQQTKTELVESNSQLQQTKTEL--VESNSQLQQTKTELVESNSQL 996 Query: 1165 N---TELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELR 1221 TEL E +++ Q ETL + + + + K++L Q + E +N+ + E + Sbjct: 997 QQTKTELVESNSQLQQTETLLQKSNSQSQQTKSLLIEFKTQLHQTDEERENMQIQLQETQ 1056 Query: 1222 SSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQE 1281 + + Q + E+ Q ++ + QK + QL +S+ E+ L Q+ ++ Sbjct: 1057 AVLQEI--QTQWRKTEILLQQSQSQQQNVQKELVGTKSQLIETKSELEK-LQYQQAILRD 1113 Query: 1282 ETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEI 1327 ++ T ++ + + +L +QE+ + EI R+E+ Sbjct: 1114 LKSEGKTEYKLLVWEAWYAYQNNNLAEMQERLQKSLKYTEISRTEV 1159 Score = 103 bits (246), Expect = 5e-20 Identities = 144/725 (19%), Positives = 312/725 (43%), Gaps = 56/725 (7%) Query: 851 LQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRI 910 L K+N+ILL E + + + ++ L E ++ + E KY TQL E+ L Sbjct: 283 LGKQNKILLVELEKYK---NQDEKSQLELTEVKSQLIQIQDELEKYITQLDGTEAKLS-- 337 Query: 911 THEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNN 970 E Q + K+K E ++E T+++S + + + EK + + EA+L E + Sbjct: 338 --ESQQQLHNKEKVYEKSQLEL-TEVKSQLTKTQ---DDLEKYVSQLNGTEAKLSESQQQ 391 Query: 971 IENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQ 1030 + N E K LEL + V+ Q T++ D E+Y++++N A L + Q Sbjct: 392 LHNKEKVYE---KSQLELTE--VKSQLTKTQDDLEKYVSQLNGTEAKLSESQ-------Q 439 Query: 1031 KINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDD 1090 +++N + + D K+ Q TK + + E+ QL ++K + Q ++E++ Sbjct: 440 QLHNKE-KVLEKTQDEFQKVQQIQTKFDQTKNELATAKSQLNETKTELIQCQSELKEKEG 498 Query: 1091 QIKELKETK---LTFEMNIPKTEGMIIS--STIEPMSDDANNVDXXXXXXXXXXXXLKVQ 1145 ++++ + T+ L + + +T+G ++ S + ++ LK Q Sbjct: 499 ELQKYQGTQKELLETQSKLDETQGELVQYQSQLHQNLEELEKNICKLQEAELAWKELKFQ 558 Query: 1146 EE--EEFIQERSVLQEQS-AKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSK 1202 E EE + + +Q+ A+L Y I+L+T +L + +QL +K Sbjct: 559 LETNEELLDKFKFQDKQNQAELGQTKHSLYETKIKLKTSQNQLHKTQEFWESSQSQLVAK 618 Query: 1203 LEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLS 1262 L +L L + S + + E+ + +Q+L++ + + +++L Sbjct: 619 EVVLKKYQQDLQDAEKALEDTYSQ-LQRTQIELG-VTRQNLSESKGELFIYKYQLHQSQE 676 Query: 1263 AFESKYEQLLDSVQSSTQEETNKIV-TMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIE 1321 +E KY+ L + +E +++ EQ Q+KL + E L+ + + + +++E Sbjct: 677 EWE-KYQSQLAGTEVLLEEYHSQLKQATEQKQQTQSKLTETEAILQAKEAELTESNSELE 735 Query: 1322 ILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSS 1381 ++ E+E + + ++ Q QS L E Q K++ Sbjct: 736 KIKLELE------RSGSDLQKTHQEVEKNQSQLKQAEEQKQQTQSKLTETEAILQAKEAE 789 Query: 1382 XXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQL 1441 + L+ THQ EL+ +I + ++ LT+ N + ++ + Sbjct: 790 LTESNSELEKIKLELERSGSDLQKTHQ-ELQ--QIQSQLNQTQADLTESNSQLKDKETRW 846 Query: 1442 VEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIE---ELNVKITES 1498 + E ++++ + +++ I + ++H+ + Q +++ +++L+E +L TE Sbjct: 847 EKSEAELKEIQ-KSQNKWEISKSELHKTKQELKRSQLQNQELQIELVESNSQLQQTKTEL 905 Query: 1499 VSLNKQ-------VAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASS 1551 V N Q + E N L++ + E + L+ + E+V N ++ + + S+ Sbjct: 906 VESNSQLQQTKTELVESNSQLQQTKTELVESNSQLQQTKTELVESNSQLQQTKTELVESN 965 Query: 1552 SKIQK 1556 S++Q+ Sbjct: 966 SQLQQ 970 Score = 49.6 bits (113), Expect = 7e-04 Identities = 70/412 (16%), Positives = 172/412 (41%), Gaps = 17/412 (4%) Query: 297 KQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTES 356 KQ+ E + ++++ E ++ A ELT+ LE + ++ ++ +L+ + Sbjct: 700 KQATEQKQQTQSKLTETEAILQAKEAELTESNSELEKIKLELERSGSDLQKTHQEVEKNQ 759 Query: 357 KAVSSPSKKGSPLISRKSGRNTASKMK-SPWSQLSSETLNQDTDKKINKNEIAKLEMVIQ 415 + ++ S+ + + K + ++ +SE + + + +++ K +Q Sbjct: 760 SQLKQAEEQKQQTQSKLTETEAILQAKEAELTESNSELEKIKLELERSGSDLQKTHQELQ 819 Query: 416 SLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDV 475 + L + ++E ++ + + ++Q + S +H + Sbjct: 820 QIQSQLNQTQADLTESNSQLKDKETRWEKSEAELKEIQKSQNKWEISKSELH-----KTK 874 Query: 476 NEIAKVQEQLKQELNDEIKDVN--VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNH 533 E+ + Q Q QEL E+ + N ++ +L + Q+ Q E+ +N + + K+ Sbjct: 875 QELKRSQLQ-NQELQIELVESNSQLQQTKTELVESNSQLQQTKTELVESNSQLQQTKTEL 933 Query: 534 KLKLKQMQKT----IDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYD 589 Q+Q+T +++ S++ + E+V +L ++ E + + LV+ + Sbjct: 934 VESNSQLQQTKTELVESNSQLQQTKTELVESNSQLQQTKTELVESNSQLQQTKTELVESN 993 Query: 590 SG-RMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADIS 648 S + ++++ + +++ ET L+ + Q L+ E + DE + + I Sbjct: 994 SQLQQTKTELVESNSQLQQ-TETLLQKSNSQSQQTKSLLIEFKTQLHQTDEERENM-QIQ 1051 Query: 649 QLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLE 700 ++ V EI++ + +I L S+ + V + L K QL T +LE Sbjct: 1052 LQETQAVLQEIQTQWRKTEI-LLQQSQSQQQNVQKELVGTKSQLIETKSELE 1102 Score = 40.3 bits (90), Expect = 0.43 Identities = 34/147 (23%), Positives = 63/147 (42%), Gaps = 8/147 (5%) Query: 1433 EFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELN 1492 E V+ QL++ + +E + + A K+ E+ +K E +++L E + Sbjct: 307 ELTEVKSQLIQIQDELEKYITQLDGTEA----KLSESQQQLHNKEKVYEKSQLELTEVKS 362 Query: 1493 VKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSS 1552 L K V++LN AK +E Q L N+E E+T +++ + + Sbjct: 363 QLTKTQDDLEKYVSQLNGT----EAKLSESQQQLHNKEKVYEKSQLELTEVKSQLTKTQD 418 Query: 1553 KIQKHVSFASDTKQGRDEQLDNTMNKE 1579 ++K+VS + T+ E NKE Sbjct: 419 DLEKYVSQLNGTEAKLSESQQQLHNKE 445 >UniRef50_Q232U4 Cluster: Putative uncharacterized protein; n=1; Tetrahymena thermophila SB210|Rep: Putative uncharacterized protein - Tetrahymena thermophila SB210 Length = 1038 Score = 122 bits (294), Expect = 8e-26 Identities = 208/1065 (19%), Positives = 443/1065 (41%), Gaps = 115/1065 (10%) Query: 555 KEIVRLTEELHHLSQKVAELEEE-KGNLQLHLVDYDS----GRMIESDVYKKMIEM---- 605 K++ +LT+ + L+ K E E+ K +Q + D G I + YK+ ++ Sbjct: 14 KKVAQLTKVIFFLNTKNDEYEQNLKAVVQAYEQQLDQTVKEGNQIITK-YKEALDKASKN 72 Query: 606 ENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLE 665 E+LA +K ++ +K QE +QK +E E +L + D E + ++ Sbjct: 73 EDLANQVMKMKQQIDQEKQQSQQEFTKYKQKCEEKEGQLIRECAKKIDTYKQECEGFKVK 132 Query: 666 EQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLE 725 I+ L+ + L VI N + +K+ + D ++ + N L +++ +DL D+LE Sbjct: 133 --IEQLTTN---LDKVINNSESNKKNHQKELADYVKEQNEKYNDL---LKKKLDLEDQLE 184 Query: 726 KMSAE------KISELLAKI-----NHEEQSKIQTQ----------FGIDAKIQERDLYI 764 K AE KI EL KI N + QS+ + ++ K +E I Sbjct: 185 KRDAEIAQLKKKIDELNKKIMDDLKNQKGQSQQMLEELKKNYENKIADLEGKNKELLQKI 244 Query: 765 ENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELV 824 +++E+E+ + ++ E + + D R L++ ++ +QE+QK +++ + Sbjct: 245 QSLEAEIQSLRMQLNNRETELKTVSDERNQLKKMTERQALQIQEQQKEIDGLKVEKQQNF 304 Query: 825 NRLAVLMDHDRVVEKQLLEIEHENKELQKKNQI---------------LLEENQNL---Q 866 ++ L ++ +EK++ + + + + K N + L ++N+ + + Sbjct: 305 EKIKQLEAANQALEKKIKDYQDQLDKYGKDNNMKDSEIGTLRKQFEKTLFDKNEEIKGVR 364 Query: 867 ISLSDMQQHYNALVEKANRTDL-AESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEI 925 L ++Q+ Y+ L + T E+E+ + Q+ DL +K + E +L + ++ Sbjct: 365 AQLMELQKQYDLLQIQLKTTQAEREAENREKDAQIADLLKQVKALQEEIASLSNNSEGQL 424 Query: 926 EDLEIEFNTQIESAIRDKKVLNEKYEKNI-----EYVTQLEAQLQEYKNNIENLNMNVEE 980 + L+ + + K+ L E Y + +Y+ Q+E ++Y+ I L + Sbjct: 425 KQLQEKLKQKTLEFEDSKRTLIEDYSNQLSAQEKKYLQQIEDLKRDYEQKIRQLTQENSQ 484 Query: 981 LNKMNLELIDKHVQKQQTQSPDYTEQYINEI----NKLNALLKQKDEEIIALNQKINNAQ 1036 ++ ++ ++K + + + QY N KL ++++ E+I LN++I Q Sbjct: 485 KEASLIQKYEEQLKKLRDEMDEQKRQYENNAGSMEKKLQQTIEKQQEQINGLNKQITELQ 544 Query: 1037 VSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELK 1096 ++ + K + ++ Q +S + +Q N + RE + +I+ LK Sbjct: 545 TRIQNLENTINQKDLDINQRDSMIQSLKQTISDLEIKFQQQNADGSSRQRELEIEIQNLK 604 Query: 1097 ETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSV 1156 ++ E IE + ++AN +++Q E E RS Sbjct: 605 KSLEDQERK--------YRDEIERLKNNANG------ELSDTIARMRIQYEGEMNAMRSQ 650 Query: 1157 LQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLST 1216 Q + +L + E +++ L +L Q + L SKL+Q E ++ + Sbjct: 651 HQSEITRLERQKNE------EIKNLRDQLNLLKEQMQNDSSDLLSKLKQREQEYEDQIKQ 704 Query: 1217 VAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQ 1276 + + + ++++ +Q L Q + ++ +LR QL E + + L +Q Sbjct: 705 INQRHNYELKLIEEKN-------QQMLNQTKTYYEDELKKLREQL---EFEKTKALQKLQ 754 Query: 1277 SSTQEETNKI-VTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFX 1335 + E K+ T E + +K DK+ L E+ + ++++L+ ++EDE+ A Sbjct: 755 DEKEAEIAKLKQTHEDKLTSLSKNFDKQ-----LAERQQEFETKMKLLQKKVEDEEKA-H 808 Query: 1336 XXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRV 1395 D ++N+ KQ ++ I +++ E LK+ Sbjct: 809 FSTKEELKTTQTNLTDQISQNKDLKQKTDKQIFDMSAEIKALKQQMEELIQQQTEALL-A 867 Query: 1396 NDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEK 1455 D + + ++ +Q K+ E+ +K +E + + ++ E + Q +E+ ++E EK Sbjct: 868 RDQQVEGIKRDYQ--RKEEEVLRKANE--LVNRKIAEQLEFIEQMKIEF-NQVESALTEK 922 Query: 1456 ESELAILRLKMHENANHYETMQKESEIERVKLIE-ELNVKITESVSLNKQVAELNKALEE 1514 L + + + + +IE +KL++ E+ K E LN+Q+ L Sbjct: 923 YVRLENDYNDLQQMFE--DRPSRPEDIETIKLLQAEIMRKEQEIGKLNEQMKFFKLELIN 980 Query: 1515 EVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVS 1559 N+M A N + ++ D+ V S+K+ S Sbjct: 981 RENNYNKMFNA--NPNVGVMNPLDQKGQTAMRVLPQSNKLISQTS 1023 Score = 118 bits (285), Expect = 1e-24 Identities = 158/796 (19%), Positives = 341/796 (42%), Gaps = 48/796 (6%) Query: 771 LSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVL 830 LS ++C+ +A + + L K D+ L+ +AY + Q + N+ ++ Sbjct: 5 LSDLHHKMCK---KVAQLTKVIFFLNTKNDEYEQNLKAVVQAYEQQLDQTVKEGNQ--II 59 Query: 831 MDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQ----HYNALVEKANRT 886 + ++K + N+ ++ K QI E+ Q+ Q Q+ + E A + Sbjct: 60 TKYKEALDKASKNEDLANQVMKMKQQIDQEKQQSQQEFTKYKQKCEEKEGQLIRECAKKI 119 Query: 887 DLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVL 946 D + E ++ ++ L +NL ++ + ++ +KE+ D E N + ++ K L Sbjct: 120 DTYKQECEGFKVKIEQLTTNLDKVINNSESNKKNHQKELADYVKEQNEKYNDLLKKKLDL 179 Query: 947 NEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQ 1006 ++ EK + QL+ ++ E I + N + ++ LE + K+ + + ++ Sbjct: 180 EDQLEKRDAEIAQLKKKIDELNKKIMDDLKNQKGQSQQMLEELKKNYENKIADLEGKNKE 239 Query: 1007 YINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQR 1066 + +I L A EI +L ++NN + + VSD ++L + T + +E Q+ Sbjct: 240 LLQKIQSLEA-------EIQSLRMQLNNRETE-LKTVSDERNQLKKMTERQALQIQEQQK 291 Query: 1067 VSKQLLDSKQHN----EELQILVREQDDQIKELKE--TKLTFEMNIPKTEGMIISSTIEP 1120 L KQ N ++L+ + + +IK+ ++ K + N+ +E + E Sbjct: 292 EIDGLKVEKQQNFEKIKQLEAANQALEKKIKDYQDQLDKYGKDNNMKDSEIGTLRKQFEK 351 Query: 1121 MSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLET 1180 D N L+ Q + IQ ++ E+ A+ + + + Q++ Sbjct: 352 TLFDKNE---EIKGVRAQLMELQKQYDLLQIQLKTTQAEREAENREKDAQIADLLKQVKA 408 Query: 1181 LNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWK 1240 L E+ ++ Q+ QL+ KL+Q E ++ T+ E S+ SA +++ + E K Sbjct: 409 LQEEIASLSNNSEGQLKQLQEKLKQKTLEFEDSKRTLIEDYSNQLSAQEKKYLQQIEDLK 468 Query: 1241 QHLAQREADFQKTEHELRVQL-SAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKL 1299 + Q+ + + L +E + ++L D + ++ N +ME+ LQ + Sbjct: 469 RDYEQKIRQLTQENSQKEASLIQKYEEQLKKLRDEMDEQKRQYENNAGSMEK--KLQQTI 526 Query: 1300 QDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAF-XXXXXXXXXXXXXXXXDLRTENQS 1358 + ++E + L ++ ++ +I+ L + I + + +++ + Q+ Sbjct: 527 EKQQEQINGLNKQITELQTRIQNLENTINQKDLDINQRDSMIQSLKQTISDLEIKFQQQN 586 Query: 1359 YKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRV-NDAEAKVLELTHQLELK---DS 1414 Q L I +N LKKS R+ N+A ++ + ++ ++ + Sbjct: 587 ADGSSRQRELEIEIQN--LKKSLEDQERKYRDEIERLKNNANGELSDTIARMRIQYEGEM 644 Query: 1415 EIYQKTHEYTITL--TQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANH 1472 + H+ IT Q+N+E +N+R QL ++++++ + L+ L+ + E + Sbjct: 645 NAMRSQHQSEITRLERQKNEEIKNLRDQLNLLKEQMQN---DSSDLLSKLKQREQEYEDQ 701 Query: 1473 YETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEE-EVAKTNEMQTALENQEI 1531 + + + E +KLIEE N ++ + EL K E+ E KT +Q + +E Sbjct: 702 IKQINQRHNYE-LKLIEEKNQQMLNQTKTYYE-DELKKLREQLEFEKTKALQKLQDEKEA 759 Query: 1532 EIVTL----NDEITNL 1543 EI L D++T+L Sbjct: 760 EIAKLKQTHEDKLTSL 775 Score = 98.3 bits (234), Expect = 2e-18 Identities = 192/963 (19%), Positives = 420/963 (43%), Gaps = 106/963 (11%) Query: 147 LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXX 206 L K +D A V+++K +I + QE K + E + + Sbjct: 66 LDKASKNEDLANQVMKMKQQIDQEKQQSQQEFTKYKQKCEEKEGQLIRECAKKIDTYKQE 125 Query: 207 XXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFE 266 +Q T + + E+ K+ ++ L ++ ++ + + L + LE + Sbjct: 126 CEGFKVKIEQLTTNLDKVINNSESNKKNHQKELADYVKEQNEKYNDLLKKKLDLEDQLEK 185 Query: 267 ISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEK-GSLEIANMTELT 325 E ++L +++++ ++Q +E E K E K LE N EL Sbjct: 186 RDAEIAQLKKKIDELNKKIMDDLKNQKGQSQQMLE---ELKKNYENKIADLEGKNK-ELL 241 Query: 326 KKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSP 385 +KI+ LE +I+ +L N+ TE K VS + + R++ ++ Sbjct: 242 QKIQSLE---AEIQSLRMQLNNR----ETELKTVSDERNQLKKMTERQA-------LQIQ 287 Query: 386 WSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISE--KDTXXXXXXXXXX 443 Q + L +K+ N +I +LE Q+L K + D + + + KD Sbjct: 288 EQQKEIDGLK--VEKQQNFEKIKQLEAANQALEKKIKDYQDQLDKYGKDNNMKDSEIGTL 345 Query: 444 GKDTLIAQLQLEHQQHMEGPSLIHVGTNTE-DVNEIAKVQEQLKQELNDEIKDVNVKDLI 502 K + + + ++G + + D+ +I Q ++E + KD + DL+ Sbjct: 346 RKQ--FEKTLFDKNEEIKGVRAQLMELQKQYDLLQIQLKTTQAEREAENREKDAQIADLL 403 Query: 503 EKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTI--DNFSKVSDSNKEIVRL 560 +++K+ +E+I L++ + K + + L+ + ++T+ D +++S K+ ++ Sbjct: 404 KQVKALQEEIASLSNNSEGQLKQLQEKLKQKTLEFEDSKRTLIEDYSNQLSAQEKKYLQQ 463 Query: 561 TEEL-HHLSQKVAELEEEKGNLQLHLVD-YDSG-RMIESDVYKKMIEMENLA---ETRL- 613 E+L QK+ +L +E + L+ Y+ + + ++ ++ + EN A E +L Sbjct: 464 IEDLKRDYEQKIRQLTQENSQKEASLIQKYEEQLKKLRDEMDEQKRQYENNAGSMEKKLQ 523 Query: 614 KAISLLESQKFDLVQELHILQQKYDEVEDKL--ADISQLQSDQVCSEIK------SVHLE 665 + I + Q L +++ LQ + +E+ + D+ Q D + +K + + Sbjct: 524 QTIEKQQEQINGLNKQITELQTRIQNLENTINQKDLDINQRDSMIQSLKQTISDLEIKFQ 583 Query: 666 EQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLE 725 +Q S+ ++EL + I+NLK +++D E D + +L+N N +L+D + Sbjct: 584 QQNADGSSRQRELEIEIQNLK-------KSLEDQERKYRDEIERLKN--NANGELSDTIA 634 Query: 726 KMSAEKISELLA-KINHE-EQSKIQTQFGIDAK--IQERDLYIENIESE----LSKYKSR 777 +M + E+ A + H+ E ++++ Q + K + +L E ++++ LSK K R Sbjct: 635 RMRIQYEGEMNAMRSQHQSEITRLERQKNEEIKNLRDQLNLLKEQMQNDSSDLLSKLKQR 694 Query: 778 ICRLEESIAVMEDR-RYSL-------ERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAV 829 E+ I + R Y L ++ +Q +Y +++ K E E E L Sbjct: 695 EQEYEDQIKQINQRHNYELKLIEEKNQQMLNQTKTYYEDELKKLREQL--EFEKTKALQK 752 Query: 830 LMDHDRVVEKQLLEIEHENK--ELQKK-NQILLEENQNLQISLSDMQQ--------HYNA 878 L D ++ E L+ HE+K L K ++ L E Q + + +Q+ H++ Sbjct: 753 LQD-EKEAEIAKLKQTHEDKLTSLSKNFDKQLAERQQEFETKMKLLQKKVEDEEKAHFST 811 Query: 879 LVE----KANRTD-LAESESTKYQT--QLRDLESNLKRITHEHQTLIVQ-------KKKE 924 E + N TD +++++ K +T Q+ D+ + +K + + + LI Q + ++ Sbjct: 812 KEELKTTQTNLTDQISQNKDLKQKTDKQIFDMSAEIKALKQQMEELIQQQTEALLARDQQ 871 Query: 925 IEDLEIEFNTQIESAIRD-KKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNK 983 +E ++ ++ + E +R +++N K + +E++ Q++ + + ++ + + +E N Sbjct: 872 VEGIKRDYQRKEEEVLRKANELVNRKIAEQLEFIEQMKIEFNQVESALTEKYVRLE--ND 929 Query: 984 MNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMV 1043 N +Q+ P E I I L A + +K++EI LN+++ ++ ++ Sbjct: 930 YN------DLQQMFEDRPSRPED-IETIKLLQAEIMRKEQEIGKLNEQMKFFKLELINRE 982 Query: 1044 SDY 1046 ++Y Sbjct: 983 NNY 985 >UniRef50_A0D4V9 Cluster: Chromosome undetermined scaffold_38, whole genome shotgun sequence; n=5; Oligohymenophorea|Rep: Chromosome undetermined scaffold_38, whole genome shotgun sequence - Paramecium tetraurelia Length = 1636 Score = 122 bits (294), Expect = 8e-26 Identities = 209/1085 (19%), Positives = 448/1085 (41%), Gaps = 69/1085 (6%) Query: 480 KVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVK--------- 530 K++++LK+ D +KD N +L+ KL E + + L A N+ ++K Sbjct: 495 KLEQELKEARQDSLKDKN--NLLMKLAQVESEKSDLELREQVARDNLEELKIQKEQVERD 552 Query: 531 -----SNHKLKL-KQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLH 584 N K++L +Q+Q+ K + NK++ R T + +K L E+K Sbjct: 553 LKLESENEKIELTRQIQELKGQVLKAEEFNKDMERNTLFGNSEFEKERALLEQKITFFEK 612 Query: 585 LVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKL 644 LV+ + + ++ K + E+ +++ + ++ + L Q+L LQ+K +E+E++L Sbjct: 613 LVNEMNAKEVDYQNEIKNLRKEHSLQSKDQQTKSDQTVR-QLQQKLSDLQEKLNEMENEL 671 Query: 645 AD-ISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIK-DLEND 702 + S ++D E K L +Q + + L I K ++EQ+ +K D N Sbjct: 672 IEKESNFENDFKKFEHKERSLTKQNLEQNEQIQALTREIREYKRNEEQMQQMLKSDANNQ 731 Query: 703 KEDIMNKLQNY--IQENMDLTDKLEKMSAEKISELL-AKINHEEQSKIQTQFGIDAKIQE 759 +++ K+Q + + D K K +EK L+ K+ E + + I+ + Sbjct: 732 VNELLEKVQGLEDLIKTKDDQLKQAKSHSEKDKALMQQKMEFMEVQLDEYKKQIEENKKS 791 Query: 760 RDLYIENIE--SELSKYKSRICRLEE-------SIAVMEDRRYSLERKADQLGSYLQEKQ 810 + ++ E S S YK ++ + + +E+ S++++ Q L E+ Sbjct: 792 HEAIMKAFENSSNESTYKIDAAKMNDLREQHKRDLKNIENEYESVKKRLQQQVDQLNERN 851 Query: 811 KAYS-EYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQ-KKNQILLEENQNLQIS 868 + + +L+N + L + + E+Q ++ +NK L +K IL E+ Q Sbjct: 852 SELELKVKFETGDLINEIENLKEQLQTSEEQKNKLLEQNKTLDGQKLSILKEQELRYQKK 911 Query: 869 LSDMQQHYN-ALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIED 927 + ++Q + A + A + A++++ + TQL+ N I E + ++KE D Sbjct: 912 IKQLEQAMDEADTKTAREVNQAQAKAEESLTQLK----NFYEIERERLERRICEEKEKSD 967 Query: 928 LEIEFNTQIESAIRDKKVLNEKYEKNIEYV-TQLEAQLQEYKNNIENLNMNVEELNKMNL 986 +F E + + YE+ IE + L Q+Q+Y N I+ + + L + + Sbjct: 968 K--KFQAAQEEFYHKLRETEQNYEEEIETLKDDLRDQVQQYTNTIQQYDHEI-ALKQQTI 1024 Query: 987 ELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDY 1046 E+ +KH++ + EQ I+ N N L+Q+ + + + S +++ Sbjct: 1025 EIFEKHIK-------EIKEQLISLQNNNNTTLEQQMNSFTTERKSLISKNDVLSSQLNNL 1077 Query: 1047 ESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNI 1106 + + K + +E E R +Q +Q +E Q RE D+++E K+ +L +MN Sbjct: 1078 QKEHMALQQKKDLLENEKTRKEQQF---EQSRKEWQEEKRELIDRLEETKQ-RLQ-KMND 1132 Query: 1107 PKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNT 1166 E I ++ N + +E I+++ E S +L Sbjct: 1133 EFLEKKIEYGRETALTQQQNEFLQKKIEDLQKQIDTQQSRFDEKIKQQK--NEYSVELEQ 1190 Query: 1167 ELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISS 1226 +L+ + +ET ++ N+ Q N+ S LE+ L + ++ + S Sbjct: 1191 KLERAQEEKTAIETKYEKIKKQLKENEYQYNKQASTLEREKAILTEKLGQLDSRKNELES 1250 Query: 1227 AVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKI 1286 + +A+ Q A+ + + EL + F + EQ + + T E +K Sbjct: 1251 KIKDESASVAQYQTALREQIAAEKKSLQQELE-KYKQFNLQLEQ--EKSEIHTSYERDKA 1307 Query: 1287 VTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXX 1346 + + L+ + + ++ L + +K+ + ++ RS +DE+ Sbjct: 1308 LWEGKFQFLEQQKEQAKQDLMDALKKFEMTLMHLQRARSNEKDEQE--NNLNELLLSVER 1365 Query: 1347 XXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELT 1406 + NQ+++++ + I ++K +E K E+ Sbjct: 1366 KYQSQIEEANQTHQRIVQDYEDKIRRLQKEVKTHRDKILIDQHGKIGNQLLSEKKFAEML 1425 Query: 1407 HQLELKDSEI--YQKTHEYTITLTQR--NDEFENVRQQLVEYEKRIEDLTYEKES---EL 1459 + EI ++ +Y I Q+ E EN++ ++VE E + +++ ++ + E Sbjct: 1426 DNEKRLQQEIENIKQDRDYKIFEYQKMLEQERENLKAKIVELETKYKEVENKRSTLIFEF 1485 Query: 1460 AILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKT 1519 R K + + +H ++ E + KL ++ + E+ L + +++ + Sbjct: 1486 EKERAKWNLDRDHLNNIKTELSDQLEKLSDKKEQLLRENEKLKNEQRATRRSVAAHNMTS 1545 Query: 1520 NEMQT 1524 N ++T Sbjct: 1546 NNIKT 1550 Score = 121 bits (291), Expect = 2e-25 Identities = 219/1099 (19%), Positives = 454/1099 (41%), Gaps = 110/1099 (10%) Query: 508 AEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQ---KTIDNFSKVSDSNKEIVRLTEEL 564 A E +L E+ A ++ +K K+N +KL Q++ ++ +V+ N E +++ +E Sbjct: 489 AFETQKKLEQELKEARQDSLKDKNNLLMKLAQVESEKSDLELREQVARDNLEELKIQKEQ 548 Query: 565 HHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENL-AETRLKAISLLESQK 623 K+ E E EK L + + G++++++ + K +E L + + L QK Sbjct: 549 VERDLKL-ESENEKIELTRQIQEL-KGQVLKAEEFNKDMERNTLFGNSEFEKERALLEQK 606 Query: 624 F----DLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELA 679 LV E++ + Y L LQS + KS Q+ + +E Sbjct: 607 ITFFEKLVNEMNAKEVDYQNEIKNLRKEHSLQSKD--QQTKSDQTVRQLQQKLSDLQEKL 664 Query: 680 LVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKI 739 +EN ++KE + END + +K ++ ++N++ ++++ ++ E I E K Sbjct: 665 NEMENELIEKE------SNFENDFKKFEHKERSLTKQNLEQNEQIQALTRE-IREY--KR 715 Query: 740 NHEE-----QSKIQTQFG-IDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRY 793 N E+ +S Q + K+Q + I+ + +L + KS E+ A+M+ + Sbjct: 716 NEEQMQQMLKSDANNQVNELLEKVQGLEDLIKTKDDQLKQAKS---HSEKDKALMQQKME 772 Query: 794 SLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQK 853 +E + D+ ++E +K++ + N +D ++ + + E ++L+ Sbjct: 773 FMEVQLDEYKKQIEENKKSHEAIMKAFENSSNESTYKIDAAKMNDLR----EQHKRDLKN 828 Query: 854 KNQILLEENQNLQISLSDMQQHYNALVEKAN-RTDLAESESTKYQTQLRDLESNLKRITH 912 + LQ + + + + L K T +E + QL+ E ++ Sbjct: 829 IENEYESVKKRLQQQVDQLNERNSELELKVKFETGDLINEIENLKEQLQTSEEQKNKLLE 888 Query: 913 EHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIE 972 +++TL QK +++ E+ + +I+ ++ ++E K V Q +A+ +E ++ Sbjct: 889 QNKTLDGQKLSILKEQELRYQKKIKQL---EQAMDEADTKTAREVNQAQAKAEESLTQLK 945 Query: 973 NL-NMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQK 1031 N + E L + E +K +K Q ++ +KL + +EEI L Sbjct: 946 NFYEIERERLERRICEEKEKSDKKFQAAQEEF-------YHKLRETEQNYEEEIETLKDD 998 Query: 1032 INNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQ 1091 + + Y + + Y+ ++A +E E+ ++ + +QL+ + +N Sbjct: 999 LRDQVQQYTNTIQQYDHEIALKQQTIEIFEKHIKEIKEQLISLQNNN------------- 1045 Query: 1092 IKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXL---KVQEEE 1148 T L +MN TE + S + +S NN+ L K ++E+ Sbjct: 1046 -----NTTLEQQMNSFTTERKSLISKNDVLSSQLNNLQKEHMALQQKKDLLENEKTRKEQ 1100 Query: 1149 EFIQERSVLQEQSAKLNTELQECYTKIIQL--ETLNTELT-GHDVVNQEQINQ-LKSKLE 1204 +F Q R QE+ +L L+E ++ ++ E L ++ G + +Q N+ L+ K+E Sbjct: 1101 QFEQSRKEWQEEKRELIDRLEETKQRLQKMNDEFLEKKIEYGRETALTQQQNEFLQKKIE 1160 Query: 1205 ----QLNTENDNLLSTVAELRSSISSAVDQR---------GFEIA-ELWKQHLAQREADF 1250 Q++T+ + + ++ S ++Q+ E E K+ L + E + Sbjct: 1161 DLQKQIDTQQSRFDEKIKQQKNEYSVELEQKLERAQEEKTAIETKYEKIKKQLKENEYQY 1220 Query: 1251 QKTEHELRVQLSAFESKYEQL---LDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLR 1307 K L + + K QL + ++S ++E+ + + T+L+ ++ +++ L+ Sbjct: 1221 NKQASTLEREKAILTEKLGQLDSRKNELESKIKDESASVAQYQ--TALREQIAAEKKSLQ 1278 Query: 1308 NLQEKYADVINQIEILRSEI----EDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQ-M 1362 EKY Q+E +SEI E +K + DL + ++ + Sbjct: 1279 QELEKYKQFNLQLEQEKSEIHTSYERDKALWEGKFQFLEQQKEQAKQDLMDALKKFEMTL 1338 Query: 1363 QEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQ--KT 1420 NE++ Q + ++ +A + E K + + KT Sbjct: 1339 MHLQRARSNEKDEQENNLNELLLSVERKYQSQIEEANQTHQRIVQDYEDKIRRLQKEVKT 1398 Query: 1421 HEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKES 1480 H I + D+ + QL+ +K E L EK + I +K + +E QK Sbjct: 1399 HRDKILI----DQHGKIGNQLLSEKKFAEMLDNEKRLQQEIENIKQDRDYKIFE-YQKML 1453 Query: 1481 EIERVKLIEELNVKITESVSLNKQVAELNKAL----EEEVAKTNEMQTALENQEIEIVTL 1536 E ER E L KI E + K+V L E+E AK N + L N + E+ Sbjct: 1454 EQER----ENLKAKIVELETKYKEVENKRSTLIFEFEKERAKWNLDRDHLNNIKTELSDQ 1509 Query: 1537 NDEITNLQNMVRASSSKIQ 1555 +++++ + + + K++ Sbjct: 1510 LEKLSDKKEQLLRENEKLK 1528 Score = 105 bits (253), Expect = 8e-21 Identities = 202/1070 (18%), Positives = 466/1070 (43%), Gaps = 104/1070 (9%) Query: 246 KDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCE 305 K+V + ++ + L+ AR + + + L +L Q +A+ ++E Sbjct: 486 KNVAFETQKKLEQELKEARQDSLKDKNNLLMKLAQVESEKSDLELREQ-VARDNLEELKI 544 Query: 306 EKTEIEEKGSLEIAN-MTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSK 364 +K ++E LE N ELT++I+ L+ + + NK++E +E + + + Sbjct: 545 QKEQVERDLKLESENEKIELTRQIQELKGQVLKAEEFNKDMERNTLFGNSEFEKERALLE 604 Query: 365 KGSPLISRKSGRNTASKM--KSPWSQLSSETLNQDTDKKINKNE-IAKLEMVIQSLNKDL 421 + + A ++ ++ L E Q D++ ++ + +L+ + L + L Sbjct: 605 QKITFFEKLVNEMNAKEVDYQNEIKNLRKEHSLQSKDQQTKSDQTVRQLQQKLSDLQEKL 664 Query: 422 VDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPS--LIHVGTNTEDVNEIA 479 + E + EK++ K+ + + LE + ++ + + N E + ++ Sbjct: 665 NEMENELIEKESNFENDFKKFEHKERSLTKQNLEQNEQIQALTREIREYKRNEEQMQQML 724 Query: 480 K------VQEQLK--QELNDEIKDVN-----VKDLIEKLKSAEEQITQLND-EIDAANKN 525 K V E L+ Q L D IK + K EK K+ +Q + + ++D K Sbjct: 725 KSDANNQVNELLEKVQGLEDLIKTKDDQLKQAKSHSEKDKALMQQKMEFMEVQLDEYKKQ 784 Query: 526 MIKVKSNHKLKLKQMQKTID------NFSKVSDSNKEIVRLTEELHH--------LSQKV 571 + + K +H+ +K + + + + +K++D ++ R + + + L Q+V Sbjct: 785 IEENKKSHEAIMKAFENSSNESTYKIDAAKMNDLREQHKRDLKNIENEYESVKKRLQQQV 844 Query: 572 AELEEEKGNLQLHLVDYDSGRMI-ESDVYKKMIEMENLAETRL---------KAISLLES 621 +L E L+L V +++G +I E + K+ ++ + +L + +S+L+ Sbjct: 845 DQLNERNSELELK-VKFETGDLINEIENLKEQLQTSEEQKNKLLEQNKTLDGQKLSILKE 903 Query: 622 QKFDLVQELHILQQKYDEVEDKLA-DISQLQS--DQVCSEIKSVH-LE-EQIDALSASKK 676 Q+ +++ L+Q DE + K A +++Q Q+ ++ +++K+ + +E E+++ +K Sbjct: 904 QELRYQKKIKQLEQAMDEADTKTAREVNQAQAKAEESLTQLKNFYEIERERLERRICEEK 963 Query: 677 ELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMD-LTDKLEKMSAE-KISE 734 E + + + +E+ Y +++ E + E+ + L++ +++ + T+ +++ E + + Sbjct: 964 EKS--DKKFQAAQEEFYHKLRETEQNYEEEIETLKDDLRDQVQQYTNTIQQYDHEIALKQ 1021 Query: 735 LLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICR---LEESIAVMEDR 791 +I + +I+ Q I + + + S ++ KS I + L + ++ Sbjct: 1022 QTIEIFEKHIKEIKEQL-ISLQNNNNTTLEQQMNSFTTERKSLISKNDVLSSQLNNLQKE 1080 Query: 792 RYSLERKADQLGSYLQEKQKAYS----EYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHE 847 +L++K D L + K++ + E+ ++ EL++RL + + + LE + Sbjct: 1081 HMALQQKKDLLENEKTRKEQQFEQSRKEWQEEKRELIDRLEETKQRLQKMNDEFLE---K 1137 Query: 848 NKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNL 907 E ++ + ++N+ LQ + D+Q+ + +++ + + + +Y +L E L Sbjct: 1138 KIEYGRETALTQQQNEFLQKKIEDLQKQIDT--QQSRFDEKIKQQKNEYSVEL---EQKL 1192 Query: 908 KRITHEHQTLIVQK----KKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQ 963 +R E +T I K KK++++ E ++N Q + R+K +L EK + +LE++ Sbjct: 1193 ER-AQEEKTAIETKYEKIKKQLKENEYQYNKQASTLEREKAILTEKLGQLDSRKNELESK 1251 Query: 964 LQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDE 1023 +++ ++ + E + + + ++K + Q EQ +EI+ K E Sbjct: 1252 IKDESASVAQYQTALREQIAAEKKSLQQELEKYK-QFNLQLEQEKSEIHTSYERDKALWE 1310 Query: 1024 -EIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQ 1082 + L Q+ A+ M + +E L N ++E + +LL S + + Q Sbjct: 1311 GKFQFLEQQKEQAKQDLMDALKKFEMTLMHLQRARSNEKDEQENNLNELLLSVERKYQSQ 1370 Query: 1083 I---------LVREQDDQIKEL-KETKLTFEMNIPKTEGMIISSTIEP-----MSDDANN 1127 I +V++ +D+I+ L KE K + + G I + + M D+ Sbjct: 1371 IEEANQTHQRIVQDYEDKIRRLQKEVKTHRDKILIDQHGKIGNQLLSEKKFAEMLDNEKR 1430 Query: 1128 VDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTK----IIQLETLNT 1183 + + ++ QER L+ + +L T+ +E K I + E Sbjct: 1431 LQQEIENIKQDRDYKIFEYQKMLEQERENLKAKIVELETKYKEVENKRSTLIFEFEKERA 1490 Query: 1184 ELT-GHDVVNQ------EQINQLKSKLEQLNTENDNLLSTVAELRSSISS 1226 + D +N +Q+ +L K EQL EN+ L + R S+++ Sbjct: 1491 KWNLDRDHLNNIKTELSDQLEKLSDKKEQLLRENEKLKNEQRATRRSVAA 1540 Score = 105 bits (253), Expect = 8e-21 Identities = 195/942 (20%), Positives = 399/942 (42%), Gaps = 128/942 (13%) Query: 689 KEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKIS-ELLAKINHEEQSKI 747 K + T K LE +++ Q+ +++ +L KL ++ +EK EL ++ + ++ Sbjct: 486 KNVAFETQKKLE---QELKEARQDSLKDKNNLLMKLAQVESEKSDLELREQVARDNLEEL 542 Query: 748 QTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQ 807 + Q + ERDL +E+ E+E + +I L+ + E+ +ER G+ Sbjct: 543 KIQ----KEQVERDLKLES-ENEKIELTRQIQELKGQVLKAEEFNKDMERNT-LFGNSEF 596 Query: 808 EKQKAYSEYTIQE-DELVNRL-AVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNL 865 EK++A E I ++LVN + A +D+ ++ E ++K+ Q K+ + + L Sbjct: 597 EKERALLEQKITFFEKLVNEMNAKEVDYQNEIKNLRKEHSLQSKDQQTKSDQTVRQ---L 653 Query: 866 QISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEI 925 Q LSD+Q+ N + +L E ES + E++ K+ H+ ++L Q Sbjct: 654 QQKLSDLQEKLNEM-----ENELIEKES--------NFENDFKKFEHKERSLTKQN---- 696 Query: 926 EDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMN 985 +E N QI++ R+ + +Y++N E Q++ L+ NN +N +E++ + Sbjct: 697 ----LEQNEQIQALTREIR----EYKRNEE---QMQQMLKSDANN--QVNELLEKVQGLE 743 Query: 986 LELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSD 1045 + K Q +Q +S ++ + + K+ + Q DE ++I + S+ +++ Sbjct: 744 DLIKTKDDQLKQAKSHSEKDKALMQ-QKMEFMEVQLDE----YKKQIEENKKSHEAIMKA 798 Query: 1046 YESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMN 1105 +E+ + T K++ + R + D K E + + + Q+ +L E E+ Sbjct: 799 FENSSNESTYKIDAAKMNDLR-EQHKRDLKNIENEYESVKKRLQQQVDQLNERNSELELK 857 Query: 1106 IPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLN 1165 + G +I+ IE + + + +++ + +++ L Q + Sbjct: 858 VKFETGDLINE-IENLKEQLQTSE---------------EQKNKLLEQNKTLDGQKLSIL 901 Query: 1166 TELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSIS 1225 E + Y K +++ L + D ++NQ ++K E+ T+ N E Sbjct: 902 KEQELRYQK--KIKQLEQAMDEADTKTAREVNQAQAKAEESLTQLKNFYEIERE------ 953 Query: 1226 SAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNK 1285 +++R E E + + +F H+LR +E + E L D ++ Q+ TN Sbjct: 954 -RLERRICEEKEKSDKKFQAAQEEFY---HKLRETEQNYEEEIETLKDDLRDQVQQYTNT 1009 Query: 1286 IVTMEQVTSL-QNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXX 1344 I + +L Q ++ E+H++ ++E+ + N + +E + +F Sbjct: 1010 IQQYDHEIALKQQTIEIFEKHIKEIKEQLISLQNNNN---TTLEQQMNSFTTERKSLISK 1066 Query: 1345 XXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLE 1404 L + + +Q++ L NE+ + ++ ++ E E Sbjct: 1067 NDVLSSQLNNLQKEHMALQQKKDLLENEKTRKEQQFEQSRKEWQEEKRELIDRLE----E 1122 Query: 1405 LTHQLELKDSEIYQKTHEY--TITLTQRNDEF--------------------ENVRQQLV 1442 +L+ + E +K EY LTQ+ +EF E ++QQ Sbjct: 1123 TKQRLQKMNDEFLEKKIEYGRETALTQQQNEFLQKKIEDLQKQIDTQQSRFDEKIKQQKN 1182 Query: 1443 EY----EKRIEDLTYEKES-ELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITE 1497 EY E+++E EK + E ++K N Y+ ++ S +ER K I +TE Sbjct: 1183 EYSVELEQKLERAQEEKTAIETKYEKIKKQLKENEYQYNKQASTLEREKAI------LTE 1236 Query: 1498 SV-SLNKQVAELNKALEEEVAKTNEMQTALENQ-EIEIVTLNDEITNLQNM-VRASSSKI 1554 + L+ + EL +++E A + QTAL Q E +L E+ + ++ K Sbjct: 1237 KLGQLDSRKNELESKIKDESASVAQYQTALREQIAAEKKSLQQELEKYKQFNLQLEQEKS 1296 Query: 1555 QKHVSFASDTK--QGRD---EQLDNTMNKELLDAVPRAELDL 1591 + H S+ D +G+ EQ ++L+DA+ + E+ L Sbjct: 1297 EIHTSYERDKALWEGKFQFLEQQKEQAKQDLMDALKKFEMTL 1338 Score = 87.8 bits (208), Expect = 2e-15 Identities = 181/976 (18%), Positives = 404/976 (41%), Gaps = 82/976 (8%) Query: 145 THLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXX 204 T N+ EK+ AL L+ K+ E + ++ K E D E KN Sbjct: 589 TLFGNSEFEKERAL--LEQKITFFEKLVNEMNAK--EVDYQNEIKNLRKEHSLQSKDQQT 644 Query: 205 XXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLE----EANKLL 260 + +Q+++ +QE ME E +++ D + + + SL E N+ + Sbjct: 645 KSDQTVRQ-LQQKLSDLQEKLNEMENELIEKESNFENDFKKFEHKERSLTKQNLEQNEQI 703 Query: 261 EAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTE-IEEKGSLEIA 319 +A EI E+ + ++++Q Q +E + K + +++ S Sbjct: 704 QALTREIR-EYKRNEEQMQQMLKSDANNQVNELLEKVQGLEDLIKTKDDQLKQAKSHSEK 762 Query: 320 NMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTA 379 + + +K+E +E Q+ + K++E + KA + S + + I + Sbjct: 763 DKALMQQKMEFME---VQLDEYKKQIEENKKSHEAIMKAFENSSNESTYKIDAAKMNDLR 819 Query: 380 SKMKSPWSQLSSE------TLNQDTDKKINKNEIAKLEMVIQSLNKDLVDK-EYVISEKD 432 + K + +E L Q D+ +N ++LE+ ++ DL+++ E + + Sbjct: 820 EQHKRDLKNIENEYESVKKRLQQQVDQLNERN--SELELKVKFETGDLINEIENLKEQLQ 877 Query: 433 TXXXXXXXXXXGKDTLIAQ-LQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELND 491 T TL Q L + +Q + I D + +E + + Sbjct: 878 TSEEQKNKLLEQNKTLDGQKLSILKEQELRYQKKIKQLEQAMDEADTKTAREVNQAQAKA 937 Query: 492 EIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKV- 550 E +K+ E + E+ ++ +E + ++K + KL++ ++ + + Sbjct: 938 EESLTQLKNFYEIERERLER--RICEEKEKSDKKFQAAQEEFYHKLRETEQNYEEEIETL 995 Query: 551 -SDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEME-NL 608 D ++ + T + ++A ++ + H+ + + + +E + N Sbjct: 996 KDDLRDQVQQYTNTIQQYDHEIALKQQTIEIFEKHIKEIKEQLISLQNNNNTTLEQQMNS 1055 Query: 609 AETRLKAI----SLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHL 664 T K++ +L SQ +L +E LQQK D +E++ Q Q +Q E + Sbjct: 1056 FTTERKSLISKNDVLSSQLNNLQKEHMALQQKKDLLENEKTRKEQ-QFEQSRKEWQE-EK 1113 Query: 665 EEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMD----- 719 E ID L +K+ L + + L+K+ YG L + + + K +Q+ +D Sbjct: 1114 RELIDRLEETKQRLQKMNDEF-LEKKIEYGRETALTQQQNEFLQKKIEDLQKQIDTQQSR 1172 Query: 720 LTDKLEKMSAEKISELLAKINH--EEQSKIQTQFG-IDAKIQERDLYIENIESELSKYKS 776 +K+++ E EL K+ EE++ I+T++ I +++E + S L + K+ Sbjct: 1173 FDEKIKQQKNEYSVELEQKLERAQEEKTAIETKYEKIKKQLKENEYQYNKQASTLEREKA 1232 Query: 777 RICRLEESIAVMEDRRYSLERKA-DQLGSY-----------------LQEKQKAYSEYTI 818 L E + ++ R+ LE K D+ S LQ++ + Y ++ + Sbjct: 1233 I---LTEKLGQLDSRKNELESKIKDESASVAQYQTALREQIAAEKKSLQQELEKYKQFNL 1289 Query: 819 QEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQ-HYN 877 Q ++ + + + D+ + + + + KE K++ L++ + +++L +Q+ N Sbjct: 1290 QLEQEKSEIHTSYERDKALWEGKFQFLEQQKEQAKQD--LMDALKKFEMTLMHLQRARSN 1347 Query: 878 ALVEKANR-TDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQI 936 E+ N +L S KYQ+Q+ + +RI +++ I + +KE++ + Sbjct: 1348 EKDEQENNLNELLLSVERKYQSQIEEANQTHQRIVQDYEDKIRRLQKEVKTHRDKILIDQ 1407 Query: 937 ESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQ 996 I ++ + +K+ + ++ +L+ QE +N ++ + + E KM +++ + Sbjct: 1408 HGKIGNQLLSEKKFAEMLDNEKRLQ---QEIENIKQDRDYKIFEYQKM----LEQERENL 1460 Query: 997 QTQSPDYTEQYINEINKLNALLKQKDEEIIALN---QKINNAQV---SYMSMVSDYESKL 1050 + + + +Y NK + L+ + ++E N +NN + + +SD + +L Sbjct: 1461 KAKIVELETKYKEVENKRSTLIFEFEKERAKWNLDRDHLNNIKTELSDQLEKLSDKKEQL 1520 Query: 1051 AQFTTKLENMEEEMQR 1066 + KL+N + +R Sbjct: 1521 LRENEKLKNEQRATRR 1536 >UniRef50_A0CY92 Cluster: Chromosome undetermined scaffold_31, whole genome shotgun sequence; n=3; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_31, whole genome shotgun sequence - Paramecium tetraurelia Length = 980 Score = 122 bits (294), Expect = 8e-26 Identities = 187/896 (20%), Positives = 415/896 (46%), Gaps = 93/896 (10%) Query: 481 VQEQLKQELNDEIKDVNV-KDLIEK----LKSAEEQITQLN------DEIDAANKNMIKV 529 +QE+LKQ + ++K++ + K IEK L+ +QI Q ++I+ A K +K Sbjct: 38 LQEELKQNESQKLKEIEIIKVEIEKGLHHLQEKNQQIEQQTVTIQELEQINHALKEELKQ 97 Query: 530 KSNHKLKLKQMQKT-IDN-FSKVSDSNKEIVRLT------EELHHL---------SQKVA 572 K KLK ++ K I+ + + N++I + T E+++H SQK+ Sbjct: 98 KEEQKLKEIEIIKVEIEKGLHHLQEKNQQIEQQTATIQELEQINHALQEELKENESQKLK 157 Query: 573 ELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAET----------RLKAISLLESQ 622 E+E K + + R+ +S+ +++ + +N ++ + K + +E Sbjct: 158 EIEINKVENRKRSSSFGKKRINKSNSKQQLFKNQNQKKSCTQRRNQSRKKNKNQNEIEII 217 Query: 623 KFDLVQELHILQQKYDEVEDKLADISQL-QSDQVCSEIKSVHLEEQIDALSASKKELALV 681 K ++ + LH LQ+K ++E + A I +L Q + E E+++ + K E+ Sbjct: 218 KVEIEKGLHHLQEKNQQIEQQSATIQELEQKNHALKEELKQKEEQKLKEIEIIKVEIEKG 277 Query: 682 IENLKLDKEQL---YGTIKDLENDKEDIMNKL-QNYIQENMDLTDKLEKMSAEK-ISELL 736 + +L+ +Q+ TI++LE + +L QN Q+ ++ ++ K+ EK + L Sbjct: 278 LHHLQEKNQQIEQQTATIQELEQKNHALQEELKQNESQKLKEI--EIIKVEIEKGLHHLQ 335 Query: 737 AKINHEEQSKIQTQFGIDAKIQERDLY-IENIESELSKYKSRICRLEESIAVMEDRRYSL 795 K EQ Q + ++++ + ++ IE + + L+E +E + ++ Sbjct: 336 EKNQQIEQQTKQKNHALQEELKQNESQKLKEIEIIKVEIGQGLHHLQEKNQQIEQQSATI 395 Query: 796 ERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKN 855 + + +Q LQE+ K E ++E E +N++ +EK L ++ +N+++++++ Sbjct: 396 Q-ELEQKNHALQEELKQKEEQKLKEIE-INKVE--------IEKGLHHLQEKNQQIEQQS 445 Query: 856 QILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQT-QLRDLESNLKRITHEH 914 + E Q +L ++ +EK +++ + Q+ +++LE + E Sbjct: 446 ATIQELEQKKSCTLRRTKKLIKVEIEKGLHHLQEKNQQIEQQSATIKELEQKNHALQEEL 505 Query: 915 QTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENL 974 + QK KEIE +++E + + I + +K+ TQ +E K N E+ Sbjct: 506 KQKEEQKLKEIEIIKVEIGQESINRIVISNYSRIRIKKSC--TTQ-----EELKEN-ESQ 557 Query: 975 NMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINN 1034 + E+ K+ +E H+Q++ Q T I E+ ++N LK++ +E +QK+ Sbjct: 558 KLKEIEIIKVEIEKGLHHLQEKNQQIEQQTAT-IQELEQINHALKEELKE--NESQKLKE 614 Query: 1035 AQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQ-IK 1093 ++ + ++ Q L+ +++++ S + + +Q N L+ ++++++Q +K Sbjct: 615 IEI--------IKVEIGQGLHHLQEKNQQIEQQSATIQELEQKNHALKEELKQKEEQKLK 666 Query: 1094 ELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQE 1153 E++ K+ E + + + + + LK Q+EE+ ++E Sbjct: 667 EIEIIKVEIEKGLHH-----LQEKNQQIEQQTVTIQELEQKNHALKEELK-QKEEQKLKE 720 Query: 1154 RSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKS-KLEQLNTENDN 1212 +++ Q + LQE +I Q EL + QE++ + +S KL+++ Sbjct: 721 IEIIKVQIGQGLHHLQEKNQQIEQQSATIQELEQKNHALQEELKENESQKLKEIEIIKVE 780 Query: 1213 LLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLL 1272 + V L+ + ++Q+ I EL +++ A +E QK E +L+ ++ + + E+ L Sbjct: 781 IGQGVHHLQEK-NQQIEQQSAIIKELEQKNHALQEELKQKEEQKLK-EIEIIKVEIEKGL 838 Query: 1273 DSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIE 1328 +Q Q+ + VT++++ + LQ++ L++ + + +IEI++ EIE Sbjct: 839 HHLQEKNQQIEQQSVTIQELEQKNHALQEE------LKQNESQKLKEIEIIKVEIE 888 Score = 120 bits (288), Expect = 4e-25 Identities = 202/1015 (19%), Positives = 454/1015 (44%), Gaps = 94/1015 (9%) Query: 595 ESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQ 654 +S+ K E L + + + +E K ++ + LH LQ+K ++E + I +L +Q Sbjct: 29 KSNKQKNHALQEELKQNESQKLKEIEIIKVEIEKGLHHLQEKNQQIEQQTVTIQEL--EQ 86 Query: 655 VCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYI 714 + +K + L +++ IE +K++ E+ +++ E +Q Sbjct: 87 INHALK--------EELKQKEEQKLKEIEIIKVEIEKGLHHLQEKNQQIEQQTATIQELE 138 Query: 715 QENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFG---IDAKIQERDLY-IENIESE 770 Q N L ++L++ ++K+ E+ +IN E K + FG I+ ++ L+ +N + Sbjct: 139 QINHALQEELKENESQKLKEI--EINKVENRKRSSSFGKKRINKSNSKQQLFKNQNQKKS 196 Query: 771 LSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEY--TIQEDELVNRLA 828 ++ +++ + ++ +E + +E+ +LQEK + + TIQE E N A Sbjct: 197 CTQRRNQSRKKNKNQNEIEIIKVEIEKGL----HHLQEKNQQIEQQSATIQELEQKNH-A 251 Query: 829 VLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQ---ISLSDMQQHYNALVEKANR 885 + + + E++L EIE E++K L E+NQ ++ ++ +++Q +AL E+ + Sbjct: 252 LKEELKQKEEQKLKEIEIIKVEIEKGLHHLQEKNQQIEQQTATIQELEQKNHALQEELKQ 311 Query: 886 TDLAESESTKYQTQLR-DLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKK 944 ES+ K ++ ++E L + ++Q + Q K++ L+ E +++ + Sbjct: 312 N---ESQKLKEIEIIKVEIEKGLHHLQEKNQQIEQQTKQKNHALQEELKQNESQKLKEIE 368 Query: 945 VLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYT 1004 ++ + + + + LQE IE + ++EL + N L ++ QK++ + + Sbjct: 369 IIKVEIGQGLHH-------LQEKNQQIEQQSATIQELEQKNHALQEELKQKEEQKLKEIE 421 Query: 1005 EQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKL-AQFTTKLENMEEE 1063 + EI K L++K+++I + I + + + + + L +++E+ Sbjct: 422 INKV-EIEKGLHHLQEKNQQIEQQSATIQELEQKKSCTLRRTKKLIKVEIEKGLHHLQEK 480 Query: 1064 MQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSD 1123 Q++ +Q K+ ++ L +++K+ +E KL E+ I K E I +I + Sbjct: 481 NQQIEQQSATIKELEQKNHAL----QEELKQKEEQKLK-EIEIIKVE--IGQESINRIV- 532 Query: 1124 DANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNT 1183 +N + E + ++E +++ + K LQE +I Q Sbjct: 533 -ISNYSRIRIKKSCTTQEELKENESQKLKEIEIIKVEIEKGLHHLQEKNQQIEQQTATIQ 591 Query: 1184 ELTGHDVVNQEQINQLKS-KLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQH 1242 EL + +E++ + +S KL+++ + + L+ + ++Q+ I EL +++ Sbjct: 592 ELEQINHALKEELKENESQKLKEIEIIKVEIGQGLHHLQEK-NQQIEQQSATIQELEQKN 650 Query: 1243 LAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDK 1302 A +E QK E +L+ ++ + + E+ L +Q Q+ + VT++++ + L K Sbjct: 651 HALKEELKQKEEQKLK-EIEIIKVEIEKGLHHLQEKNQQIEQQTVTIQELEQKNHAL--K 707 Query: 1303 EEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQM 1362 EE L++K + +IEI++ +I L+ +NQ +Q Sbjct: 708 EE----LKQKEEQKLKEIEIIKVQI------------------GQGLHHLQEKNQQIEQ- 744 Query: 1363 QEQSILNINEEN----AQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDS---E 1415 Q +I + ++N +LK++ + + E Q+E + + E Sbjct: 745 QSATIQELEQKNHALQEELKENESQKLKEIEIIKVEIGQGVHHLQEKNQQIEQQSAIIKE 804 Query: 1416 IYQKTHEYTITLTQRNDE-FENVRQQLVEYEKRIEDLTYEKES-ELAILRLKMHENANH- 1472 + QK H L Q+ ++ + + VE EK + L + + E + ++ E NH Sbjct: 805 LEQKNHALQEELKQKEEQKLKEIEIIKVEIEKGLHHLQEKNQQIEQQSVTIQELEQKNHA 864 Query: 1473 YETMQKESEIERVKLIEELNVKITESV----SLNKQVAELNKALEEEVAKTNEMQTAL-- 1526 + K++E +++K IE + V+I + + N+Q+ + ++E K + +Q L Sbjct: 865 LQEELKQNESQKLKEIEIIKVEIEKGLHHLQEKNQQIEQQTVTIQELEQKNHALQEELKQ 924 Query: 1527 -ENQEI-EIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKE 1579 E+Q++ EI + EI + ++ + +I++ + + +Q + NK+ Sbjct: 925 NESQKLKEIEIIKVEIGQGLHHLQEKNQQIEQQSATIQELEQKNHALQEELKNKQ 979 Score = 109 bits (263), Expect = 5e-22 Identities = 162/787 (20%), Positives = 347/787 (44%), Gaps = 48/787 (6%) Query: 477 EIAKVQEQLKQELNDEIKD--VNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKV---KS 531 EI K L QE N +I+ +++L +K + +E++ Q +E +IKV K Sbjct: 220 EIEKGLHHL-QEKNQQIEQQSATIQELEQKNHALKEELKQ-KEEQKLKEIEIIKVEIEKG 277 Query: 532 NHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEEL-HHLSQKVAELEEEKGNLQ--LHLVDY 588 H L+ K Q+ + + + ++ L EEL + SQK+ E+E K ++ LH + Sbjct: 278 LHHLQEKN-QQIEQQTATIQELEQKNHALQEELKQNESQKLKEIEIIKVEIEKGLHHLQE 336 Query: 589 DSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADIS 648 + ++ + K E L + + + +E K ++ Q LH LQ+K ++E + A I Sbjct: 337 KNQQIEQQTKQKNHALQEELKQNESQKLKEIEIIKVEIGQGLHHLQEKNQQIEQQSATIQ 396 Query: 649 QL-QSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQL---YGTIKDLENDKE 704 +L Q + E E+++ + +K E+ + +L+ +Q+ TI++LE K Sbjct: 397 ELEQKNHALQEELKQKEEQKLKEIEINKVEIEKGLHHLQEKNQQIEQQSATIQELEQKKS 456 Query: 705 DIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYI 764 + + + I+ ++ + ++I + A I EQ Q + K +++ I Sbjct: 457 CTLRRTKKLIKVEIEKGLHHLQEKNQQIEQQSATIKELEQKNHALQEELKQKEEQKLKEI 516 Query: 765 ENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELV 824 E I+ E+ + I R I + R +++ + + + E I + E+ Sbjct: 517 EIIKVEIG--QESINR----IVISNYSRIRIKKSCTTQEELKENESQKLKEIEIIKVEIE 570 Query: 825 NRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEE-NQNLQISLSDMQQHYNALVEKA 883 L L + ++ +E+Q I+ EL++ N L EE +N L +++ + + Sbjct: 571 KGLHHLQEKNQQIEQQTATIQ----ELEQINHALKEELKENESQKLKEIEIIKVEIGQGL 626 Query: 884 NRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDK 943 + + + +++LE + E + QK KEIE +++E IE + Sbjct: 627 HHLQEKNQQIEQQSATIQELEQKNHALKEELKQKEEQKLKEIEIIKVE----IEKGLHHL 682 Query: 944 KVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDY 1003 + N++ E+ + +LE + K ++ EE +E+I + Q Q + Sbjct: 683 QEKNQQIEQQTVTIQELEQKNHALKEELK----QKEEQKLKEIEII----KVQIGQGLHH 734 Query: 1004 TEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEE 1063 ++ +I + +A +++ +++ AL +++ + + + + ++ Q L+ ++ Sbjct: 735 LQEKNQQIEQQSATIQELEQKNHALQEELKENESQKLKEIEIIKVEIGQGVHHLQEKNQQ 794 Query: 1064 MQRVSKQLLDSKQHNEELQILVREQDDQ-IKELKETKLTFEMNIPKTEGMIISSTIEPMS 1122 +++ S + + +Q N LQ ++++++Q +KE++ K+ E + + + IE S Sbjct: 795 IEQQSAIIKELEQKNHALQEELKQKEEQKLKEIEIIKVEIEKGLHHLQEK--NQQIEQQS 852 Query: 1123 DDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLN 1182 ++ LK Q E + ++E +++ + K LQE +I Q Sbjct: 853 VTIQELE---QKNHALQEELK-QNESQKLKEIEIIKVEIEKGLHHLQEKNQQIEQQTVTI 908 Query: 1183 TELTGHDVVNQEQINQLKS-KLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAEL-WK 1240 EL + QE++ Q +S KL+++ + + L+ + ++Q+ I EL K Sbjct: 909 QELEQKNHALQEELKQNESQKLKEIEIIKVEIGQGLHHLQEK-NQQIEQQSATIQELEQK 967 Query: 1241 QHLAQRE 1247 H Q E Sbjct: 968 NHALQEE 974 Score = 99 bits (238), Expect = 5e-19 Identities = 151/695 (21%), Positives = 307/695 (44%), Gaps = 90/695 (12%) Query: 216 QQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISS----LEEANKLLEAARFEISLEH 271 +Q TK + + A++ E K + + LK+IE V I L+E N+ +E + Sbjct: 342 EQQTKQKNH--ALQEELKQNESQKLKEIEIIKVEIGQGLHHLQEKNQQIE--------QQ 391 Query: 272 SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELL 331 S QELEQ +++ ++K E + K +EI N E+ K + L Sbjct: 392 SATIQELEQK---------------NHALQEELKQKEEQKLK-EIEI-NKVEIEKGLHHL 434 Query: 332 EHLNCQIRQ---TNKELENKLA-TMGTESKAVSSPSKKGSPLISRKSGR----NTASKMK 383 + N QI Q T +ELE K + T+ K + +KG + K+ + + K Sbjct: 435 QEKNQQIEQQSATIQELEQKKSCTLRRTKKLIKVEIEKGLHHLQEKNQQIEQQSATIKEL 494 Query: 384 SPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXX 443 + E L Q ++K+ + EI K+E+ +S+N+ ++ I K + Sbjct: 495 EQKNHALQEELKQKEEQKLKEIEIIKVEIGQESINRIVISNYSRIRIKKSCTTQEELKEN 554 Query: 444 G----KDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQEL--NDEIKDVN 497 K+ I ++++E H + T + E+ ++ LK+EL N+ K Sbjct: 555 ESQKLKEIEIIKVEIEKGLHHLQEKNQQIEQQTATIQELEQINHALKEELKENESQKLKE 614 Query: 498 VKDLIEKLKSAEEQITQLNDEIDAANKNMIKV-KSNHKLKLKQMQKTIDNFSKVSDSNKE 556 ++ + ++ + + N +I+ + + ++ + NH LK + QK ++ E Sbjct: 615 IEIIKVEIGQGLHHLQEKNQQIEQQSATIQELEQKNHALKEELKQKEEQKLKEIEIIKVE 674 Query: 557 IVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAI 616 I + LHHL +K ++E++ +Q +E + E++ E +LK I Sbjct: 675 I---EKGLHHLQEKNQQIEQQTVTIQ----------ELEQKNHALKEELKQKEEQKLKEI 721 Query: 617 SLLESQKFDLVQELHILQQKYDEVEDKLADISQL-QSDQVCSEIKSVHLEEQIDALSASK 675 ++ K + Q LH LQ+K ++E + A I +L Q + E + +++ + K Sbjct: 722 EII---KVQIGQGLHHLQEKNQQIEQQSATIQELEQKNHALQEELKENESQKLKEIEIIK 778 Query: 676 KELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISEL 735 E+ + +L+ +Q+ + I+ +L+ Q+N L ++L++ +K+ E+ Sbjct: 779 VEIGQGVHHLQEKNQQI--------EQQSAIIKELE---QKNHALQEELKQKEEQKLKEI 827 Query: 736 LAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYS- 794 E K++ + G+ +QE++ IE + + + + L+E + E ++ Sbjct: 828 -------EIIKVEIEKGLH-HLQEKNQQIEQQSVTIQELEQKNHALQEELKQNESQKLKE 879 Query: 795 ---LERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQ-LLEIEHENKE 850 ++ + ++ +LQEK + + T+ EL + L + + E Q L EIE E Sbjct: 880 IEIIKVEIEKGLHHLQEKNQQIEQQTVTIQELEQKNHALQEELKQNESQKLKEIEIIKVE 939 Query: 851 LQKKNQILLEENQNLQ---ISLSDMQQHYNALVEK 882 + + L E+NQ ++ ++ +++Q +AL E+ Sbjct: 940 IGQGLHHLQEKNQQIEQQSATIQELEQKNHALQEE 974 >UniRef50_A0CY31 Cluster: Chromosome undetermined scaffold_30, whole genome shotgun sequence; n=2; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_30, whole genome shotgun sequence - Paramecium tetraurelia Length = 1036 Score = 122 bits (294), Expect = 8e-26 Identities = 215/1020 (21%), Positives = 445/1020 (43%), Gaps = 106/1020 (10%) Query: 598 VYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCS 657 VYK+++ ME+ + R++ LE+Q +++ ++ + ++KY E+E L D + ++ Sbjct: 12 VYKQVV-MEHKEDERVEQ---LEAQIYNMEKDHSMWRKKYFELES-LYDKCRYAAE---- 62 Query: 658 EIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQEN 717 KSV LE++I+ L +++ ++ + E++ + LEN+ ++ N ++ Sbjct: 63 --KSVQLEDRINLLRQDNSQISALLREKATECEKMRVRLTQLENENFEL-----NTVRLQ 115 Query: 718 MDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSR 777 + + L + + I ELL K N E +++ G + I++ + ++ +L +K Sbjct: 116 VTKFNDLLQQKTQDI-ELLRKKNSEIYARVIELEGNELVIRDYKSQVNSLTKDLDVWKKL 174 Query: 778 I-CRLEESIAVMEDRRY---------SLERKADQLGSYLQEKQKAYSEYTIQEDELVNRL 827 + +E + ++E R S++ Q+ ++ + SE T +L + L Sbjct: 175 YEDQQQERVKLLEIIRQFEQNNPLSGSIKSSQQQVSEVIERRVVTTSETTNNTQQLQSSL 234 Query: 828 AVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTD 887 +E +L E + +L+++ + ++ N L+I ++ + ++ N Sbjct: 235 LQNQATISDLEDRLGFSEKQYDKLKQELEARIKMNNELKIKITQQECE----LKNINYLK 290 Query: 888 LAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQ--IESAIRDKKV 945 L ++ K + QL + L + ++ T + + + + L +N + ++ +++ Sbjct: 291 L---DNQKLKDQLDQTKRELDQFRKQYYTTLSKLQIAEQQLNELYNLENRLQLLQQERDT 347 Query: 946 LNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTE 1005 LN+ ++ E + QL+ ++ + IE L +N + N E+I Sbjct: 348 LNKSLKQKNEDIGQLQDKVSSLLSQIEQLRLNDQARNAAENEVI---------------- 391 Query: 1006 QYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQ 1065 Q E++KL A LKQK++ I L+ +IN+ Q + SD++ A+ + L++ + + Sbjct: 392 QLKTELSKLQANLKQKEQTISDLHGRINDLQKQLTNSQSDFKRLQAKDYSGLQDQAKLVN 451 Query: 1066 RVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDA 1125 + ++LL Q N + Q Q L+ + +I + ++ + T E +SD Sbjct: 452 ELQQKLLQLSQDNSKFQ-------SQAFNLESKNNSQVQDIQRLNSLLSTKTQE-LSD-- 501 Query: 1126 NNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTEL 1185 N LK Q + I E + ++ L +LQ +IIQ LNT+L Sbjct: 502 ANKKIYDLENDKTIPDLKFQ-NSQLIAELREQETENKGLQEKLQILENQIIQ---LNTKL 557 Query: 1186 TGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQ 1245 T + +N+ K+K++QL L S + +L S + VDQ ++ +Q Sbjct: 558 TTAEAQANCNLNE-KNKVDQL------LTSYLLQL-SQLEKEVDQLRVIAQQVAQQSAIN 609 Query: 1246 READFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEH 1305 ++ ++ L+ QL S++ +L + + + + Q++ L NK+Q +E Sbjct: 610 KQQ--EQLVQALQKQLKDQTSQFNELSKENEKLYVDNSQLSTRISQLSELPNKIQILDEG 667 Query: 1306 LRNLQEKYADVINQIEILRSEIEDE---KVAFXXXXXXXXXXXXXXXXDLRTENQSYKQM 1362 L+ LQ+ Y + + E L ++ D K L + +Q+ Sbjct: 668 LQKLQQDYNNELQANETLNKQLNDALKVKNDLENKIAMLSTEVERFQYKLNSRQNEAEQL 727 Query: 1363 QEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVL-ELTHQLELKDSEIYQKTH 1421 ++Q I+++ + AQLK+ ++ E +++ E LE +T Sbjct: 728 KKQ-IVDLETQIAQLKQ----LESENQVLADKIAHLEQQIINEANKNLEHLLRVSQDETK 782 Query: 1422 EYTI---TLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQ- 1477 Y + L Q+ D+ E +Q E K++E + +S L + + A + Sbjct: 783 SYVLDNNKLKQQLDQREQENKQKDESYKQLEQKYQQLQSSNKNLEAQNTQIAELQNVIAG 842 Query: 1478 KESEIERVK-LIEELNVK----ITESVSLN-------KQVAELNKALEEEVAKTNEMQT- 1524 +E++I++ + LIEEL K + ES L+ Q+A+L +E+ + N Q Sbjct: 843 QENDIQKFQDLIEELRDKNNDLVAESQKLSIELTQQQVQIADLKNQIEKLNTQVNNNQNY 902 Query: 1525 --ALENQEIEIVTLNDEITNLQNMVRASSSKIQK-HVSF-ASDTKQGRDEQLDNTMNKEL 1580 +E + +I L +E L+N V SS+I++ V + A K E+ + KEL Sbjct: 903 DQLIEELKKKIEKLQEEKYQLENKVALLSSEIERMRVKYDAQGNKLNISEEQKQGLTKEL 962 Score = 109 bits (263), Expect = 5e-22 Identities = 183/965 (18%), Positives = 418/965 (43%), Gaps = 85/965 (8%) Query: 504 KLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEE 563 +L + Q+T+ ND + +++ ++ + ++ + N + D ++ LT++ Sbjct: 108 ELNTVRLQVTKFNDLLQQKTQDIELLRKKNSEIYARVIELEGNELVIRDYKSQVNSLTKD 167 Query: 564 LHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQK 623 L + + ++E+ L + ++ + + ++ + E R+ S + Sbjct: 168 LDVWKKLYEDQQQERVKLLEIIRQFEQNNPLSGSIKSSQQQVSEVIERRVVTTSETTNNT 227 Query: 624 FDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKS-VHLEEQIDALSASKKELALV- 681 L L Q ++ED+L S+ Q D++ E+++ + + ++ + +++E L Sbjct: 228 QQLQSSLLQNQATISDLEDRLG-FSEKQYDKLKQELEARIKMNNEL-KIKITQQECELKN 285 Query: 682 IENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINH 741 I LKLD ++ L++ + +L + ++ KL+ ++ ++++EL + + Sbjct: 286 INYLKLDNQK-------LKDQLDQTKRELDQFRKQYYTTLSKLQ-IAEQQLNELY-NLEN 336 Query: 742 EEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRL---EESIAVMEDRRYSLERK 798 Q Q + ++ +++++ I ++ ++S S+I +L +++ E+ L+ + Sbjct: 337 RLQLLQQERDTLNKSLKQKNEDIGQLQDKVSSLLSQIEQLRLNDQARNAAENEVIQLKTE 396 Query: 799 ADQLGSYLQEKQKAYSEYTIQEDELVNRLA-VLMDHDRVVEKQLLEIEHENK---ELQKK 854 +L + L++K++ S+ + ++L +L D R+ K ++ + K ELQ+K Sbjct: 397 LSKLQANLKQKEQTISDLHGRINDLQKQLTNSQSDFKRLQAKDYSGLQDQAKLVNELQQK 456 Query: 855 NQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEH 914 L ++N Q +++ N+ V+ R L STK Q +L D + + ++ Sbjct: 457 LLQLSQDNSKFQSQAFNLESKNNSQVQDIQR--LNSLLSTKTQ-ELSDANKKIYDLEND- 512 Query: 915 QTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIE-N 973 K I DL+ + N+Q+ + +R+++ N+ ++ ++ + QL E Sbjct: 513 --------KTIPDLKFQ-NSQLIAELREQETENKGLQEKLQILENQIIQLNTKLTTAEAQ 563 Query: 974 LNMNVEELNKMNLELIDKHVQKQQTQSP-DYTEQYINEINKLNALLKQKDEEIIALNQKI 1032 N N+ E NK++ L +Q Q + D ++ + +A+ KQ+++ + AL +++ Sbjct: 564 ANCNLNEKNKVDQLLTSYLLQLSQLEKEVDQLRVIAQQVAQQSAINKQQEQLVQALQKQL 623 Query: 1033 NNAQVSYMSMVSDYESKL----AQFTTKLENMEEEMQRVSKQLLD------SKQHNEELQ 1082 + Q S + +S KL +Q +T++ + E ++ Q+LD + +N ELQ Sbjct: 624 KD-QTSQFNELSKENEKLYVDNSQLSTRISQLSELPNKI--QILDEGLQKLQQDYNNELQ 680 Query: 1083 ILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXL 1142 + Q+ + + K E I ++S+ +E N+ L Sbjct: 681 -ANETLNKQLNDALKVKNDLENKI-----AMLSTEVERFQYKLNSRQNEAEQLKKQIVDL 734 Query: 1143 KVQ--EEEEFIQERSVLQEQSAKLNTE-LQECYTKIIQLETLNTELTGHDVVNQEQINQL 1199 + Q + ++ E VL ++ A L + + E + L ++ + T V++ ++ Q Sbjct: 735 ETQIAQLKQLESENQVLADKIAHLEQQIINEANKNLEHLLRVSQDETKSYVLDNNKLKQQ 794 Query: 1200 KSKLEQLNTENDNLLSTVAELRSSISSA---VDQRGFEIAELWKQHLAQREADFQKTEHE 1256 + EQ N + D + + + S+ ++ + +IAEL + +A +E D QK + Sbjct: 795 LDQREQENKQKDESYKQLEQKYQQLQSSNKNLEAQNTQIAEL-QNVIAGQENDIQKFQD- 852 Query: 1257 LRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADV 1316 + K L+ Q + E T + V Q+ L+N+++ + N + Y + Sbjct: 853 ---LIEELRDKNNDLVAESQKLSIELTQQQV---QIADLKNQIEKLNTQVNN-NQNYDQL 905 Query: 1317 INQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQ 1376 I +++ ++++EK E K + + LNI+EE Q Sbjct: 906 IEELKKKIEKLQEEKYQLENKVALLSS---------EIERMRVKYDAQGNKLNISEEQKQ 956 Query: 1377 LKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFEN 1436 +++ ++ +L QL K E+ QK ++TL +E + Sbjct: 957 ------GLTKELEQVHKLFEESQDEIDKLQEQLS-KQKELEQKEQALSLTLVNAFNEIDA 1009 Query: 1437 VRQQL 1441 +RQQL Sbjct: 1010 LRQQL 1014 Score = 101 bits (243), Expect = 1e-19 Identities = 171/837 (20%), Positives = 377/837 (45%), Gaps = 69/837 (8%) Query: 309 EIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLAT-MGTESKAVSSPSKKGS 367 ++ E E + E+ ++ E L+ I+ + +++ + + T S+ ++ + S Sbjct: 173 KLYEDQQQERVKLLEIIRQFEQNNPLSGSIKSSQQQVSEVIERRVVTTSETTNNTQQLQS 232 Query: 368 PLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKN-----EIAKLEMVIQSLNKDLV 422 L+ ++ + + +S+ + L Q+ + +I N +I + E ++++N + Sbjct: 233 SLLQNQATISDLED-RLGFSEKQYDKLKQELEARIKMNNELKIKITQQECELKNINYLKL 291 Query: 423 DKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQ 482 D + + + D T +++LQ+ QQ E +L + + + + Sbjct: 292 DNQKLKDQLDQTKRELDQFRKQYYTTLSKLQIAEQQLNELYNL------ENRLQLLQQER 345 Query: 483 EQLKQELNDEIKDVN-VKDLIEKLKSAEEQITQLNDEI-DAANKNMIKVKSN-HKLK--L 537 + L + L + +D+ ++D + L S EQ+ +LND+ +AA +I++K+ KL+ L Sbjct: 346 DTLNKSLKQKNEDIGQLQDKVSSLLSQIEQL-RLNDQARNAAENEVIQLKTELSKLQANL 404 Query: 538 KQMQKTI-DNFSKVSDSNKEIVRLTEELHHLSQK-VAELEEEK---GNLQLHLVDYDSGR 592 KQ ++TI D +++D K++ + L K + L+++ LQ L+ Sbjct: 405 KQKEQTISDLHGRINDLQKQLTNSQSDFKRLQAKDYSGLQDQAKLVNELQQKLLQLSQDN 464 Query: 593 MIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQK-YDEVEDKLADISQLQ 651 S + +E+ ++++ I L S QEL +K YD DK + Q Sbjct: 465 ---SKFQSQAFNLESKNNSQVQDIQRLNSLLSTKTQELSDANKKIYDLENDKTIPDLKFQ 521 Query: 652 SDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQ 711 + Q+ +E++ E + E ++ N KL + E +K D + L Sbjct: 522 NSQLIAELREQETENKGLQEKLQILENQIIQLNTKLTTAEAQANCNLNEKNKVDQL--LT 579 Query: 712 NYIQENMDLTDKLEKMS--AEKISELLAKINHEEQSKIQ----------TQFGIDAKIQE 759 +Y+ + L +++++ A+++++ A IN +++ +Q +QF +K E Sbjct: 580 SYLLQLSQLEKEVDQLRVIAQQVAQQSA-INKQQEQLVQALQKQLKDQTSQFNELSKENE 638 Query: 760 RDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQ 819 + LY++N S+LS S++ L I ++++ L++ + + K ++ Sbjct: 639 K-LYVDN--SQLSTRISQLSELPNKIQILDEGLQKLQQDYNNELQANETLNKQLNDALKV 695 Query: 820 EDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKK-----NQI-----LLEENQNLQISL 869 +++L N++A+L + +L ++E ++L+K+ QI L ENQ L + Sbjct: 696 KNDLENKIAMLSTEVERFQYKLNSRQNEAEQLKKQIVDLETQIAQLKQLESENQVLADKI 755 Query: 870 SDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESN-LKRITHEHQTLIVQKKKEIEDL 928 + ++Q ++ +AN+ ++ +T+ L++N LK+ + + QK + + L Sbjct: 756 AHLEQQ---IINEANKNLEHLLRVSQDETKSYVLDNNKLKQQLDQREQENKQKDESYKQL 812 Query: 929 EIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENL----NMNVEELNKM 984 E ++ Q++S+ ++ + N + + + E +Q++++ IE L N V E K+ Sbjct: 813 EQKYQ-QLQSSNKNLEAQNTQIAELQNVIAGQENDIQKFQDLIEELRDKNNDLVAESQKL 871 Query: 985 NLELIDKHVQ----KQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYM 1040 ++EL + VQ K Q + + ++L LK+K E++ ++ N Sbjct: 872 SIELTQQQVQIADLKNQIEKLNTQVNNNQNYDQLIEELKKKIEKLQEEKYQLENKVALLS 931 Query: 1041 SMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKE 1097 S + K KL EE+ Q ++K+L + EE Q + + +Q+ + KE Sbjct: 932 SEIERMRVKYDAQGNKLNISEEQKQGLTKELEQVHKLFEESQDEIDKLQEQLSKQKE 988 >UniRef50_A0C7H6 Cluster: Chromosome undetermined scaffold_155, whole genome shotgun sequence; n=1; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_155, whole genome shotgun sequence - Paramecium tetraurelia Length = 1047 Score = 122 bits (294), Expect = 8e-26 Identities = 205/1023 (20%), Positives = 449/1023 (43%), Gaps = 93/1023 (9%) Query: 620 ESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELA 679 +SQ F L H L++ Y+ + D++ ++ Q DQ + K +++ ID+ A +L+ Sbjct: 58 DSQNFHLRSSQH-LEKSYN-LTDRIFSPARKQ-DQSPNLRKKENIKI-IDSYEARYGKLS 113 Query: 680 ---LVIEN-LKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISEL 735 L ++N ++ D+++ I +LE + KLQ Q N+ L + E+I L Sbjct: 114 TENLQLQNQIQADQQKYNKIINELEIQLSNQTYKLQTE-QHNIKQQQLLLQKKNEEIQLL 172 Query: 736 LAKINHEEQSKIQ-TQFGIDAKIQERDL--YIENIESELSKYKSRICRLE-ESIAVMEDR 791 + ++ E IQ +Q + + + ++L YI+N+E EL K ++ +S +E+ Sbjct: 173 VNELKKNETKFIQISQNNVQSVDENQNLKAYIQNLEYELQNLKQQVQDTHFKSARQIEET 232 Query: 792 RYSLERKAD-----QLGSYLQEKQKAYS---EYTIQEDELVNRLAVLMDHDRVVEK---Q 840 + +E QL Q+ Q+ S + IQE + ++L D+ V EK Q Sbjct: 233 KIKVENDCSHQSQIQLKDIQQQHQQILSKKNDQLIQEQQKYSKLLGQFDN-LVNEKNKMQ 291 Query: 841 LLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQL 900 LL + ++++L + Q+ + + L +M H + D + +Q Q+ Sbjct: 292 LLIDDLQDEKLVIQQQLQQQNQMCEEFRLKNMSLHKEVQLVH----DKQAKQELSHQKQI 347 Query: 901 RDLESNLKRITHEHQTLIVQKK-KEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQ 959 ++L K+ + Q +Q++ E E N Q + IR+ + ++ E N + + Sbjct: 348 QEL----KQYYEQQQINNLQRRLNETELKHSTENQQQDQIIRELQAQLQQSENNYQVMKT 403 Query: 960 LEAQL----QEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLN 1015 A+L QE + I+ L +E +NK D +Q+QQ +Q + + +K Sbjct: 404 ENAKLYAIDQEQEKEIKILQQELERINKFK----DLEIQQQQEDLQKLKQQLLEQSSKYQ 459 Query: 1016 ALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLA-QFTTKLENM----EEEMQRVSKQ 1070 L + ++ + N + ++ ++ + E+ + Q+ T ++ + ++++Q + +Q Sbjct: 460 TKLHELSKQQVIANDIKSELELQ-KNVTKEIEASIREQWETDIQELKGFNQQQLQNLEEQ 518 Query: 1071 LLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSD-DANNVD 1129 + NE+L I R++D+QI E K + + +I + + + + + + + Sbjct: 519 IKFLNLENEKLIIQSRKKDEQINEYKLNQQLLDNSINGLKHQLSDTEKQKQKELEDYQFE 578 Query: 1130 XXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHD 1189 +K+Q+E++ ++++ Q+Q AK E T I+LE +++ + Sbjct: 579 LENFKKELKEQNVKLQQEKQLMEQQLKQQKQRAK------ELETAKIELEFSSSQQIQN- 631 Query: 1190 VVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQ--RGFEIAELWKQHLAQ-- 1245 QEQI Q ++ Q N+E S + + ++ A Q + A+++ + L + Sbjct: 632 --YQEQIKQKDWQISQFNSEKQKFESLLKSNKERLTQAEFQVVELKQSADIYLKELEEST 689 Query: 1246 READFQKTEHELRVQLSAFE-SKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEE 1304 ++ D ++++ + S+Y+Q ++ + + N+I ++ SL + + + ++ Sbjct: 690 QQRDLERSQFNQKFGFQETRISQYKQAINQYEIEIHNQNNQIDKAQK--SLDHAMLESQK 747 Query: 1305 HLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQE 1364 + +++ +++QI L +++ + F L+ ++ K ++ Sbjct: 748 KIEESRKREQKLLDQIANLNLQLQSNEDQFIKYQEEHKESNKQIEQLLQEKDSLIKSLEN 807 Query: 1365 QSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYT 1424 Q E+ ++K + E + + Q+E + + + + Sbjct: 808 Q-----KEKLVEVKNELTEEIEQLNQKIQNYAEGENQRQDWEFQVENEKAVLNNEIEILQ 862 Query: 1425 ITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQ--KESEI 1482 L Q+ + ++QQ E +++D KE LR ++ +N H E + K+ I Sbjct: 863 QKLDQKESKLNQIQQQFSNLEIQLQD----KEVLYDSLRRQIDQNYVHVEDYEQLKQKNI 918 Query: 1483 ERVKLIEELN----VKITESVSLNKQVAELNKAL---EEEVAKTNEM--QTALENQEI-- 1531 + I EL +E SL +QV +L L E+E +T E + +N+++ Sbjct: 919 NLLNEIHELESSQLKSNSEKQSLRRQVEKLKSDLELKEQEFEQTFEQLNKRRGDNEDVAK 978 Query: 1532 ---EIVTLNDEITNLQNMVRASSSKI---QKHVSFASDTKQGRDEQLDNTMNKELLDAVP 1585 EI LN E+++ Q +++A S ++ ++ + QL+ T KEL+ + Sbjct: 979 LTKEIQRLNFELSDAQTLLQAKSEQLNIMRRENDDQLEQLNRMKRQLNQTSEKELIRRID 1038 Query: 1586 RAE 1588 ++E Sbjct: 1039 KSE 1041 Score = 111 bits (268), Expect = 1e-22 Identities = 129/670 (19%), Positives = 313/670 (46%), Gaps = 56/670 (8%) Query: 450 AQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKV--QEQLKQELNDEIKDVNVKDLIEKLKS 507 A+ +L HQ+ ++ + + +N + + + +LK ++ +D +++L +L+ Sbjct: 337 AKQELSHQKQIQELKQYY---EQQQINNLQRRLNETELKHSTENQQQDQIIRELQAQLQQ 393 Query: 508 AEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHL 567 +E + E N + + + ++K +Q+ ++ +K D EI + E+L L Sbjct: 394 SENNYQVMKTE----NAKLYAIDQEQEKEIKILQQELERINKFKDL--EIQQQQEDLQKL 447 Query: 568 SQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLV 627 Q++ E + K +LH + ++I +D+ K +E++ ++A S+ E + D+ Sbjct: 448 KQQLLE-QSSKYQTKLH--ELSKQQVIANDI-KSELELQKNVTKEIEA-SIREQWETDIQ 502 Query: 628 QELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKL 687 + QQ+ +E+++ ++ L+++++ I+S +EQI+ +++ L I LK Sbjct: 503 ELKGFNQQQLQNLEEQIKFLN-LENEKLI--IQSRKKDEQINEYKLNQQLLDNSINGLK- 558 Query: 688 DKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEK---MSAEKISELLAKINHEEQ 744 QL T K + + ED +L+N+ +E + KL++ + +++ + + E Sbjct: 559 --HQLSDTEKQKQKELEDYQFELENFKKELKEQNVKLQQEKQLMEQQLKQQKQRAKELET 616 Query: 745 SKIQTQFGIDAKIQ-------ERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLER 797 +KI+ +F +IQ ++D I SE K++S + +E + E + L++ Sbjct: 617 AKIELEFSSSQQIQNYQEQIKQKDWQISQFNSEKQKFESLLKSNKERLTQAEFQVVELKQ 676 Query: 798 KADQLGSYLQEKQKAYSEYTIQEDELVNRLAV----LMDHDRVVEKQLLEIEHENKELQK 853 AD YL+E +++ + ++ + + + + + + + +EI ++N ++ K Sbjct: 677 SAD---IYLKELEESTQQRDLERSQFNQKFGFQETRISQYKQAINQYEIEIHNQNNQIDK 733 Query: 854 KNQIL----LEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKR 909 + L LE + ++ S Q+ + + + E + KYQ + ++ +++ Sbjct: 734 AQKSLDHAMLESQKKIEESRKREQKLLDQIANLNLQLQSNEDQFIKYQEEHKESNKQIEQ 793 Query: 910 ITHEHQTLIVQ---KKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQE 966 + E +LI +K+++ +++ E +IE + + E + ++ Q+E + Sbjct: 794 LLQEKDSLIKSLENQKEKLVEVKNELTEEIEQLNQKIQNYAEGENQRQDWEFQVENEKAV 853 Query: 967 YKNNIENLNMNVEE----LNKMNLELIDKHVQKQQTQSP-DYTEQYINEINKLNA----L 1017 N IE L +++ LN++ + + +Q Q + D + I++ N ++ Sbjct: 854 LNNEIEILQQKLDQKESKLNQIQQQFSNLEIQLQDKEVLYDSLRRQIDQ-NYVHVEDYEQ 912 Query: 1018 LKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQH 1077 LKQK+ ++ ++ ++Q+ S ++ + + LE E+E ++ +QL + Sbjct: 913 LKQKNINLLNEIHELESSQLKSNSEKQSLRRQVEKLKSDLELKEQEFEQTFEQLNKRRGD 972 Query: 1078 NEELQILVRE 1087 NE++ L +E Sbjct: 973 NEDVAKLTKE 982 Score = 86.2 bits (204), Expect = 7e-15 Identities = 163/842 (19%), Positives = 368/842 (43%), Gaps = 78/842 (9%) Query: 220 KMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISL-EHSKLAQEL 278 +++E I +E + + Q LKDI+ + +I S + + E ++ L + L E Sbjct: 228 QIEETKIKVENDCSHQSQIQLKDIQQQHQQILSKKNDQLIQEQQKYSKLLGQFDNLVNEK 287 Query: 279 EQXXXXXXXXXXXXXXLAKQSIEPS--CEEKTEIEEKGSLEIANMTELTKKIELLEHLNC 336 + + +Q + + CEE E+ + + K EL Sbjct: 288 NKMQLLIDDLQDEKLVIQQQLQQQNQMCEEFRLKNMSLHKEVQLVHDKQAKQELSHQKQI 347 Query: 337 Q-IRQTNKELE-NKLATMGTESKAVSSPSKKGSPLISRK------SGRNTASKMKSPWSQ 388 Q ++Q ++ + N L E++ S + I R+ N MK+ ++ Sbjct: 348 QELKQYYEQQQINNLQRRLNETELKHSTENQQQDQIIRELQAQLQQSENNYQVMKTENAK 407 Query: 389 LSSETLNQDTDKKINKNEIAKL----EMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXG 444 L + Q+ + KI + E+ ++ ++ IQ +DL + + E+ + Sbjct: 408 LYAIDQEQEKEIKILQQELERINKFKDLEIQQQQEDLQKLKQQLLEQSSKYQTKLHELSK 467 Query: 445 KDTLIAQL--QLEHQQHMEGPSLIHVGTNTE-DVNEIAKVQEQLKQELNDEIKDVNVKD- 500 + + + +LE Q+++ + E D+ E+ +Q Q L ++IK +N+++ Sbjct: 468 QQVIANDIKSELELQKNVTKEIEASIREQWETDIQELKGFNQQQLQNLEEQIKFLNLENE 527 Query: 501 -LIEKLKSAEEQITQ-------LNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSD 552 LI + + +EQI + L++ I+ + + + +L+ Q ++NF K + Sbjct: 528 KLIIQSRKKDEQINEYKLNQQLLDNSINGLKHQLSDTEKQKQKELEDYQFELENFKK--E 585 Query: 553 SNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVD--YDSGRMIES---DVYKKMIEMEN 607 ++ V+L +E + Q++ + ++ L+ ++ + S + I++ + +K ++ Sbjct: 586 LKEQNVKLQQEKQLMEQQLKQQKQRAKELETAKIELEFSSSQQIQNYQEQIKQKDWQISQ 645 Query: 608 LAETRLKAISLLESQKFDLVQ-ELHILQQKYD-EVEDKLADISQLQSDQVCSEI--KSVH 663 + K SLL+S K L Q E +++ K ++ K + S Q D S+ K Sbjct: 646 FNSEKQKFESLLKSNKERLTQAEFQVVELKQSADIYLKELEESTQQRDLERSQFNQKFGF 705 Query: 664 LEEQIDAL--SASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLT 721 E +I + ++ E+ + +N ++DK Q K L++ + K++ + L Sbjct: 706 QETRISQYKQAINQYEIEIHNQNNQIDKAQ-----KSLDHAMLESQKKIEESRKREQKLL 760 Query: 722 DKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRL 781 D++ ++ + S I ++E+ K ++ I+ +QE+D I+++E++ K Sbjct: 761 DQIANLNLQLQSNEDQFIKYQEEHK-ESNKQIEQLLQEKDSLIKSLENQKEK-------- 811 Query: 782 EESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQL 841 + + + L + +QL +Q + ++ E ++ N AVL + +++++L Sbjct: 812 ------LVEVKNELTEEIEQLNQKIQNYAEGENQRQDWEFQVENEKAVLNNEIEILQQKL 865 Query: 842 LEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKA--NRTDLAESESTKYQT- 898 + KE K NQI ++ NL+I L D + Y++L + N + + E K + Sbjct: 866 -----DQKE-SKLNQIQ-QQFSNLEIQLQDKEVLYDSLRRQIDQNYVHVEDYEQLKQKNI 918 Query: 899 ----QLRDLESNLKRITHEHQTLIVQKKKEIEDLEI---EFNTQIESAIRDKKVLNEKYE 951 ++ +LES+ + E Q+L Q +K DLE+ EF E + ++ NE Sbjct: 919 NLLNEIHELESSQLKSNSEKQSLRRQVEKLKSDLELKEQEFEQTFEQ-LNKRRGDNEDVA 977 Query: 952 KNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEI 1011 K + + +L +L + + ++ + + + + N + +++ + ++ + ++ I I Sbjct: 978 KLTKEIQRLNFELSDAQTLLQAKSEQLNIMRRENDDQLEQLNRMKRQLNQTSEKELIRRI 1037 Query: 1012 NK 1013 +K Sbjct: 1038 DK 1039 Score = 85.4 bits (202), Expect = 1e-14 Identities = 157/807 (19%), Positives = 344/807 (42%), Gaps = 95/807 (11%) Query: 859 LEENQNLQISLSDMQQHYNAL-VEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQT- 916 L + +N++I + + Y L E + +++ KY + +LE L T++ QT Sbjct: 93 LRKKENIKI-IDSYEARYGKLSTENLQLQNQIQADQQKYNKIINELEIQLSNQTYKLQTE 151 Query: 917 --------LIVQKKKE-----IEDLEIEFNTQIESAIRDKKVLNEK-----YEKNIEYVT 958 L++QKK E + +L+ I+ + + + ++E Y +N+EY Sbjct: 152 QHNIKQQQLLLQKKNEEIQLLVNELKKNETKFIQISQNNVQSVDENQNLKAYIQNLEYEL 211 Query: 959 Q-LEAQLQE--YKN--NIENLNMNVEE--LNKMNLELIDKHVQKQQTQSPDYTEQYINEI 1011 Q L+ Q+Q+ +K+ IE + VE ++ ++L D Q QQ S +Q I E Sbjct: 212 QNLKQQVQDTHFKSARQIEETKIKVENDCSHQSQIQLKDIQQQHQQILSKK-NDQLIQEQ 270 Query: 1012 NKLNALLKQKDEEIIALNQ------KINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQ 1065 K + LL Q D + N+ + + ++ + +F K ++ +E+Q Sbjct: 271 QKYSKLLGQFDNLVNEKNKMQLLIDDLQDEKLVIQQQLQQQNQMCEEFRLKNMSLHKEVQ 330 Query: 1066 RV-SKQLLDSKQHNEELQILVREQDDQ-----IKELKETKLTFEMNIPKTEGMIISSTIE 1119 V KQ H +++Q L + + Q + L ET+L + + II Sbjct: 331 LVHDKQAKQELSHQKQIQELKQYYEQQQINNLQRRLNETELKHSTE-NQQQDQIIRELQA 389 Query: 1120 PMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLE 1179 + NN + +E+E +E +LQ++ ++N K ++++ Sbjct: 390 QLQQSENNYQVMKTENAKLYA---IDQEQE--KEIKILQQELERINK------FKDLEIQ 438 Query: 1180 TLNTELTGHDVVNQEQINQLKSKLEQLNTEN--DNLLSTVAELRSSISSAVDQRGFEIAE 1237 +L EQ ++ ++KL +L+ + N + + EL+ +++ ++ I E Sbjct: 439 QQQEDLQKLKQQLLEQSSKYQTKLHELSKQQVIANDIKSELELQKNVTKEIEA---SIRE 495 Query: 1238 LWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEE------TNKIVTMEQ 1291 W+ + + + Q+ L Q+ + E+L+ +QS ++E N+ + Sbjct: 496 QWETDIQELKGFNQQQLQNLEEQIKFLNLENEKLI--IQSRKKDEQINEYKLNQQLLDNS 553 Query: 1292 VTSLQNKLQD----KEEHLRNLQEKYADVINQIEILRSEIEDEK-VAFXXXXXXXXXXXX 1346 + L+++L D K++ L + Q + + +++ +++ EK + Sbjct: 554 INGLKHQLSDTEKQKQKELEDYQFELENFKKELKEQNVKLQQEKQLMEQQLKQQKQRAKE 613 Query: 1347 XXXXDLRTENQSYKQMQ--EQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLE 1404 + E S +Q+Q ++ I + + +Q R+ AE +V+E Sbjct: 614 LETAKIELEFSSSQQIQNYQEQIKQKDWQISQFNSEKQKFESLLKSNKERLTQAEFQVVE 673 Query: 1405 LTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRL 1464 L ++ E+ + T + + +Q N +F ++ +Y++ I E ++ + Sbjct: 674 LKQSADIYLKELEESTQQRDLERSQFNQKFGFQETRISQYKQAINQYEIEIHNQNNQID- 732 Query: 1465 KMHENANH--YETMQK--ESEIERVKLIEE---LNVKITES----VSLNKQVAELNKALE 1513 K ++ +H E+ +K ES KL+++ LN+++ + + ++ E NK +E Sbjct: 733 KAQKSLDHAMLESQKKIEESRKREQKLLDQIANLNLQLQSNEDQFIKYQEEHKESNKQIE 792 Query: 1514 EEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLD 1573 + + + + + +LENQ+ ++V + +E+T + + KIQ + +G +++ D Sbjct: 793 QLLQEKDSLIKSLENQKEKLVEVKNELT---EEIEQLNQKIQNYA-------EGENQRQD 842 Query: 1574 NTMNKELLDAVPRAELDLAMYMLHQRD 1600 E AV E+++ L Q++ Sbjct: 843 WEFQVENEKAVLNNEIEILQQKLDQKE 869 Score = 39.1 bits (87), Expect = 0.99 Identities = 86/442 (19%), Positives = 179/442 (40%), Gaps = 34/442 (7%) Query: 212 EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRI--SSLEEANKLLEAAR---FE 266 ++ K+Q K+Q+ ME + K +KQR K++E+ + + SS ++ E + ++ Sbjct: 584 KELKEQNVKLQQEKQLMEQQLKQQKQR-AKELETAKIELEFSSSQQIQNYQEQIKQKDWQ 642 Query: 267 ISLEHSKLA--QELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTEL 324 IS +S+ + L + KQS + +E E ++ LE ++ Sbjct: 643 ISQFNSEKQKFESLLKSNKERLTQAEFQVVELKQSADIYLKELEESTQQRDLE---RSQF 699 Query: 325 TKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKS 384 +K E Q +Q + E ++ + + S + L S+K + + + Sbjct: 700 NQKFGFQETRISQYKQAINQYEIEIHNQNNQIDK-AQKSLDHAMLESQKKIEESRKREQ- 757 Query: 385 PWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXG 444 +L + N + + N+++ K + + NK + E ++ EKD+ Sbjct: 758 ---KLLDQIANLNLQLQSNEDQFIKYQEEHKESNKQI---EQLLQEKDSLIKSLENQKEK 811 Query: 445 KDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVK-DLIE 503 + +L E +Q + G N E E K LN+EI+ + K D E Sbjct: 812 LVEVKNELTEEIEQLNQKIQNYAEGENQRQDWEFQVENE--KAVLNNEIEILQQKLDQKE 869 Query: 504 -KLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTE 562 KL ++Q + L EI +K ++ + + ++ Q ++++ ++ N + L Sbjct: 870 SKLNQIQQQFSNL--EIQLQDKEVL--YDSLRRQIDQNYVHVEDYEQLKQKN---INLLN 922 Query: 563 ELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLA----ETRLKAISL 618 E+H L + EK +L+ + S ++ +++ E N E K Sbjct: 923 EIHELESSQLKSNSEKQSLRRQVEKLKSDLELKEQEFEQTFEQLNKRRGDNEDVAKLTKE 982 Query: 619 LESQKFDLVQELHILQQKYDEV 640 ++ F+L +LQ K +++ Sbjct: 983 IQRLNFELSDAQTLLQAKSEQL 1004 >UniRef50_A5E429 Cluster: Putative uncharacterized protein; n=1; Lodderomyces elongisporus NRRL YB-4239|Rep: Putative uncharacterized protein - Lodderomyces elongisporus (Yeast) (Saccharomyces elongisporus) Length = 2032 Score = 122 bits (294), Expect = 8e-26 Identities = 255/1402 (18%), Positives = 596/1402 (42%), Gaps = 137/1402 (9%) Query: 236 KQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXL 295 K+ + K I S RI +E A ++ S S QE+ Sbjct: 198 KEEISKIINSAISRIIPIERATTTTSSSSSSSSSSSSSSTQEVVDSIAETLTNLINSGSQ 257 Query: 296 AKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTE 355 +Q +E +IE + E+ K ++ N ++++ N LE+KL + + Sbjct: 258 NQQYLELDSSSTIKIE---------LEEVKSKFSAADNDNIRLKEENDMLESKLQSSQQQ 308 Query: 356 SK----AVSSPSKKGSPLISRKSGRNTA-SKMKSPWSQLSSETLN---QDTDKKINKNEI 407 SK + K L + N +++K SQ S L+ Q T + +N Sbjct: 309 SKELQHVIEDLQDKIRHLAKSFAELNRKFAELKDTCSQQESHYLSKLEQLTSSNVEQNR- 367 Query: 408 AKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDT--LIAQLQLEHQQHMEG--- 462 KL +++ LN +KE ++ + ++ L +LQ Q++ E Sbjct: 368 -KLASLVEELNTR--EKENFANKLELTKAKSELSFLRNESKWLHEELQSSQQKYSEALKQ 424 Query: 463 PSLIHVGTNTEDVNEIAKVQ--EQLKQELNDEIKDVNVKDLIEKLKSAEEQI------TQ 514 T++ +N +K++ EQL + E+ +N E K+ + ++ TQ Sbjct: 425 SGQTQSSTDSAMLNTQSKLKNAEQLIKSHETELLQLNSSLAAETKKNTDLEVRLKKIETQ 484 Query: 515 LNDEIDAANK--NMIKVKSNHK-LKLKQMQKTIDNFSKVSDSNKEIVRLT-----EELHH 566 +I+A + +++K++S + ++K++++ ++ K SD + + L+ +E+ Sbjct: 485 SLLDINAKQELIDLMKIQSRQRESRIKELEEYVNQILKNSDEAFKHLELSVSEKDDEIAV 544 Query: 567 LSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDL 626 L +K+ +EE + ++ + Y E ++ + ISLL S+ + Sbjct: 545 LQEKLQRVEEALAADMAQTLSGENSEQTFASGYGSSSEFDSGSGPG--QISLLYSEFIHV 602 Query: 627 VQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQI-DALSASKKELALVIENL 685 +EL + + + +++E +L + + D + + + ++Q +++ ++ +++N Sbjct: 603 KKELTLERMQKEKLEGELEEFV-FEMDSLKRALGDFNAQKQYYESVRLDLQDQITILQNE 661 Query: 686 KLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQS 745 KL+ E+ + ++ D + + +L+ +++ L + + + NHE+ Sbjct: 662 KLELEKSQRHFRAVQKDNDLEVQRLKQTLKD-------LGRQLCFSLIHTKIRDNHEDPL 714 Query: 746 KIQTQFGIDAKIQERDLYIENIESELSK--------YKSRI---CRLEESIAVMEDRRYS 794 + + I+ I E ES+ SK +K I R EE ++ + + Sbjct: 715 SLAEKTFIENVIDRTGNDEEFAESDTSKLISERLLEFKDLIELRQRNEELLSAVRELSTR 774 Query: 795 LER-KADQLGSYLQEKQKAYSEYTIQEDEL---VNRLAVLMDHDRVVEKQLLEIEHENKE 850 LE +A Q + + +A + ++EL N++++L+ +EK + E + + Sbjct: 775 LESGEAAQNSAEIAAIDEAQETILMLQNELESTCNKMSLLVKERDALEKIVRERDGGDAG 834 Query: 851 LQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRI 910 K N + + + ++ ++ ++ +EK ++ K + + +++ L ++ Sbjct: 835 NDKSNGLSIANFGHNEVE-NEEKEKIRIKMEKQQEQKQKQTGEEKNEKEREEVDKELSQV 893 Query: 911 THE-HQTLIVQKKKEIE-DLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYK 968 + + + K ++E ++ Q E ++ + N++ +IE+ Q Q+ + Sbjct: 894 ILQLREVKDARDKLKVELAAQVRAIEQAELKVQSLQRTNDRLLSDIEHANQ---QVNFWN 950 Query: 969 NNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIAL 1028 E L + E + L L K +K+ T + E + ++ K + I+ L Sbjct: 951 KQFEKLEGQLNEKALLMLGLEAKLNEKETT-----VKSLCLEKDFALSMQKSLESTIVEL 1005 Query: 1029 NQ--KINNAQVSYMSMVSDYE-SKLAQFTTKLENMEEEMQRVSKQLLDSKQH----NEEL 1081 Q KI N Q + + + ++ + S+LA+ KL+++E E + ++L + + ++ Sbjct: 1006 RQDKKIMNEQFAVLQLTAETKNSELAKLAQKLDDLESERLAIQRKLNERESKILILTDQR 1065 Query: 1082 QILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDAN-NVDXXXXXXXXXXX 1140 + ++ Q +++++ + ++ K + + +E + D A+ +V Sbjct: 1066 DMSMKSQQVKLEQINDLSSQL-LHARKELSQMQAIVLELLPDSASQSVARQQMEDELKEY 1124 Query: 1141 XLKVQEEEEFIQERS-VLQEQSAKLNTELQECYTKIIQLET----LNTELTGHDVVNQEQ 1195 ++ E +++++ + E + K EL K+ ET + E+T + V + Sbjct: 1125 GDRISELTNQLKDKNETILEATTKFEKELSSMSEKLKSKETEKVAADGEITRLNGVISSK 1184 Query: 1196 INQLKSKLEQLNTENDNLLSTV--AELRSSISSAV-DQRGFEIAELWKQH-----LAQRE 1247 I ++++ +Q TE D ++ + AE ++ S +V D+ I +L Q L Q+ Sbjct: 1185 IQEMENMKKQYTTELDETVAKLKAAESKTKSSQSVEDELKKTIEDLQDQRDISKGLEQKI 1244 Query: 1248 ADFQKTEHELRVQLSAFES----------KYEQLLDSVQSSTQEETNKIVTMEQVTSLQN 1297 ++ L Q++A++S + L+ V+++ ++E N+I++ Q LQ Sbjct: 1245 REYHTQVSTLVQQINAYKSDSDSNQELIQSLQDQLEQVRATRKDEENQILS--QKLELQT 1302 Query: 1298 KLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQ 1357 + + + + LQ + ++NQ+E L S E + + ++ Sbjct: 1303 ENAELLKKIEELQGQNTLLLNQLE-LSSSSNQETNPSGEKSQDIAQIISFLRREKESSDE 1361 Query: 1358 SYKQMQEQSI-LNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEI 1416 +++E+++ L I EN Q K ++ VN+ + K + Q++L ++ Sbjct: 1362 KLPKLEEENVALKIKLENLQNKVNNFNAGAPSASINLTVNNEQQKQI----QMQLDQLKL 1417 Query: 1417 YQKTHEYTITLT-QRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYET 1475 +++++ + ++N E N+ ++ + + +E +T ++L+ L + Sbjct: 1418 FKESNSVLVNENLKKNQELVNLNSEVTKIKLELEKITQLYNNQLSHLSV----------- 1466 Query: 1476 MQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIE-IV 1534 E +RVKL + NV++ + +S N + +E K+ E+AK E L+ + + I Sbjct: 1467 -----EQQRVKLFSDENVRLKQILSANSRTSEQTKSPAPEIAKMQEQMDKLKTKANDRIA 1521 Query: 1535 TLNDEITNLQNMVRASSSKIQK 1556 L E+ + +V+A ++I+K Sbjct: 1522 VLRRELDSKDGIVKAKEAEIEK 1543 Score = 57.6 bits (133), Expect = 3e-06 Identities = 160/839 (19%), Positives = 342/839 (40%), Gaps = 81/839 (9%) Query: 141 LGDVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXX 200 L D+ H + + + L+ ++ +L L+ K+NEK+ + K+ Sbjct: 936 LSDIEHANQQVNFWNKQFEKLEGQLNEKALLMLGLEAKLNEKETTV----KSLCLEKDFA 991 Query: 201 XXXXXXXXXXXEDTKQQMTKMQENFIAME--AEWKDEK----QRLLKDIESKDVRISSL- 253 + +Q M E F ++ AE K+ + + L D+ES+ + I Sbjct: 992 LSMQKSLESTIVELRQDKKIMNEQFAVLQLTAETKNSELAKLAQKLDDLESERLAIQRKL 1051 Query: 254 -EEANKLL---EAARFEISLEHSKLAQ--ELEQXXXXXXXXXXXXXXLAKQSIEPSCEE- 306 E +K+L + + + KL Q +L + + + S + Sbjct: 1052 NERESKILILTDQRDMSMKSQQVKLEQINDLSSQLLHARKELSQMQAIVLELLPDSASQS 1111 Query: 307 --KTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSK 364 + ++E++ ++ELT + L+ N I + + E +L++M + K+ + Sbjct: 1112 VARQQMEDELKEYGDRISELTNQ---LKDKNETILEATTKFEKELSSMSEKLKSKETEKV 1168 Query: 365 KGSPLISRKSG--RNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLV 422 I+R +G + +M++ Q ++E K +++ + V L K + Sbjct: 1169 AADGEITRLNGVISSKIQEMENMKKQYTTELDETVAKLKAAESKTKSSQSVEDELKKTIE 1228 Query: 423 DKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIH-VGTNTEDVNEIAKV 481 D + TL+ Q+ LI + E V K Sbjct: 1229 DLQDQRDISKGLEQKIREYHTQVSTLVQQINAYKSDSDSNQELIQSLQDQLEQVRATRKD 1288 Query: 482 QEQ--LKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQ 539 +E L Q+L E++ N +L++K++ + Q T L ++++ ++ + + + + K + Sbjct: 1289 EENQILSQKL--ELQTENA-ELLKKIEELQGQNTLLLNQLELSSSSNQETNPSGE-KSQD 1344 Query: 540 MQKTIDNFSKVSDSNKE-IVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDV 598 + + I + +S+ E + +L EE L K+ L+ + N + ++ Sbjct: 1345 IAQIISFLRREKESSDEKLPKLEEENVALKIKLENLQNKVNNFNAGAPSASINLTVNNE- 1403 Query: 599 YKKMIEMENLAETRL--KAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVC 656 +K I+M+ L + +L ++ S+L ++ QEL L + +++ +L I+QL ++Q Sbjct: 1404 QQKQIQMQ-LDQLKLFKESNSVLVNENLKKNQELVNLNSEVTKIKLELEKITQLYNNQ-- 1460 Query: 657 SEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQE 716 + + +E+Q L + EN++L K+ L + E K + +QE Sbjct: 1461 --LSHLSVEQQRVKLFSD--------ENVRL-KQILSANSRTSEQTKSPAPEIAK--MQE 1507 Query: 717 NMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKS 776 M DKL+ K ++ +A + E SK D ++ ++ IE I+ EL + Sbjct: 1508 QM---DKLK----TKANDRIAVLRRELDSK-------DGIVKAKEAEIEKIKQELQAANA 1553 Query: 777 RICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRV 836 + E++ +V D + +E+K + L+ ++ ++ +++ELV +LA L Sbjct: 1554 K----EQNKSVNGDSK-DVEKKLADVNRELKTVKEESAKLVGEKNELVKQLATLK----- 1603 Query: 837 VEKQLLEIEHENKELQKKNQILLEENQNLQISLSDM-QQHYNALVEKANRTDLAESESTK 895 + + K + + + A A + E K Sbjct: 1604 -AQNMKSGSTAGKSVTTPTAAAVVGGATTAAGATAAGATAAGATAAGATAAAVKNGEVPK 1662 Query: 896 YQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNI 954 + Q+R+L+ +L+++ E Q + ++K + LE+E + + + +KV EKYEK + Sbjct: 1663 LEAQIRELKQSLEKMQQESQKKLDEEKSKTR-LEVEKKFEFKLRLLTRKV--EKYEKEL 1718 >UniRef50_UPI00006A0892 Cluster: Hook-related protein 1; n=1; Xenopus tropicalis|Rep: Hook-related protein 1 - Xenopus tropicalis Length = 1347 Score = 122 bits (293), Expect = 1e-25 Identities = 212/1098 (19%), Positives = 470/1098 (42%), Gaps = 92/1098 (8%) Query: 494 KDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDS 553 + ++V DL KL+ A +++ + +E+ N+ +++ KL Q + + + +S Sbjct: 171 RSLHVADLQSKLRRARQELEEKGEEL-LDNQQHVEMLEAELRKLHQQVRELSAMAALSRG 229 Query: 554 NK-EIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVY--KKMIEMENLAE 610 + E+ L E +V L E+ +++ + + K+++E + AE Sbjct: 230 YRDELDALRERSRRAEAQVNALNEKLRTMEIFQRSLQEEKEFSRALLEDKEVLEHQLAAE 289 Query: 611 T-RLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQI- 668 R + + L E +K L + + L+ + D E + + + E++ + E Q Sbjct: 290 RERSEKLRLCEKEKHSLEERIQRLEMERDS-ECQRVQFLLHDNLTLAEEVRVLREETQRG 348 Query: 669 -DALSASKKELALVIENLK--LD-KEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKL 724 + + S + V E + LD +L + LE + +++ +LQ E D +K Sbjct: 349 WERVYESHGDTVPVWEREQDVLDLNSELSQALLRLEKENQNLRERLQGLSGETPDPKNKG 408 Query: 725 EKMSAEKISELLAKIN----HEEQSKIQTQFGIDAKIQER-DLYIENIESELSKYKSRIC 779 + + E +K+ H E+S ++ Q D+ QE+ E ++ +L + I Sbjct: 409 QHVQTEGEQGRNSKVQIMTVHLEESPLE-QKSCDSYWQEKVSCETEALKRQLEESALEID 467 Query: 780 RLEESIAVMEDRRYSLERKADQLGSY---LQEKQKAYSEYTI----QEDELVNRLAVLMD 832 L+ + +D + + + + + LQ K + +E + Q D+ + +L + Sbjct: 468 SLKRQLKEKQDEAQNQQNQLSESTTEKNALQRKLQGNAEEILSLQKQLDKSIKECHLLKE 527 Query: 833 HDRVVEKQLLEIEHE--NKELQKKNQILLEENQ---NLQISLSDMQQHYNALVEKANRTD 887 + + K+ L+++H N+E+Q + + + E ++ +LQ L D+ + L ++ +D Sbjct: 528 ELQGMVKESLKMQHHDGNEEMQTQKRKVEESSEEILSLQRQLQDIVKKEELLQKQLEISD 587 Query: 888 -LAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQ---IESAIRDK 943 + E++ + ++ L+ IT E Q+L K+++E+ E E Q ++ ++ + Sbjct: 588 KMVETQHRNLAERSEEIRQ-LQEITGEVQSL----KRQLEETEKEKQCQQRHLQESVLEA 642 Query: 944 KVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDY 1003 + L ++ K +E +LE QL+E I++L ++E + E + + +Q+++ QS + Sbjct: 643 EELQKQLLKALES-KELETQLKESAKEIQSLGKQLKE--SRDAEALRRQLQEREEQS--F 697 Query: 1004 TEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEE 1063 +Q + K+ +L Q +E +S+ +++ E +LE + Sbjct: 698 KKQLQDNAEKIQSLKNQLNESTAE--------NISHEMQLTERECLEKSLKGQLEERNVD 749 Query: 1064 MQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSD 1123 + + KQL ++ EE + L R ++ +E + ++ E N+ + + + + IE Sbjct: 750 INSLQKQL---EKKTEEEKSLKRRLEENEREKQVQQIHLESNLKEVQSLKKQNQIEEREK 806 Query: 1124 DANNVDXXXXXXXXXXXXLKVQ--EEEEFIQERSVLQEQSAKLNTELQ-ECYTKIIQLET 1180 + LK Q +++E ++E+ L Q + N ++ + K +E Sbjct: 807 MEQLLKREWQVSAEEVQVLKQQLNDKQENLEEKESLLRQLLQTNDSMKRQLDEKSKHVED 866 Query: 1181 LNTELTGHDVVNQEQINQLKSKLEQLNTENDN---LLSTVAELRSSISSAVDQRGFEIAE 1237 L + + +E+I LK KL N E + +L E S+ + +R EI Sbjct: 867 LTIQFQKNLKDCEEEIQTLKWKLTDSNNELQSQKIMLERNKETEDSLKRKLVERSDEIQS 926 Query: 1238 LWKQHLAQREADFQKTEHELRVQLSAFESKYEQL--LDSVQSSTQEETNKIVTMEQVTSL 1295 L K+HL + + +QK + ++ S + + L L +++ QE T E++ SL Sbjct: 927 L-KRHLEEAKGQYQKKQEYTDMKDSP-QGQANDLGELHTLKRQLQEST------EEMQSL 978 Query: 1296 QNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTE 1355 +L++ ++ ++ ++ + +I++ + ++ED V + T Sbjct: 979 MRQLEESAAEIQTVKRQFQESAEKIQLQKRQLEDS-VGESLSLKRQLGELQESNNKIETL 1037 Query: 1356 NQSYKQMQEQ-----SILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLE 1410 + ++ +++ L + + +L+K R + + + L L+ Sbjct: 1038 QRQLQEREDEIETLERKLQESADEVELQKKQLAEMELQGVRRERA-EIQGRYDSLLKDLQ 1096 Query: 1411 LKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENA 1470 ++ ++ + E L + +RQ+ E ++R L+ + E L+ K+ E Sbjct: 1097 RQEGDLERAQRE----LRRNRSALRILRQEHQELQERFSQLSVQGEQTQQELKRKVQEQ- 1151 Query: 1471 NHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQE 1530 E ES++E L EE + L ++++ L+K LEE EM+ L + Sbjct: 1152 ---EGTIHESQLENQNLQEEQH-------RLKEELSHLDKTLEERSLDLREMKKQLGTEH 1201 Query: 1531 IEIVTLNDEITNLQNMVR 1548 E L E L+ V+ Sbjct: 1202 REKDQLERERGELREQVQ 1219 Score = 117 bits (281), Expect = 3e-24 Identities = 188/940 (20%), Positives = 402/940 (42%), Gaps = 98/940 (10%) Query: 328 IELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISR-KSGRNTASKM---- 382 ++L L+ + + KE +N + S P KG + + + GRN+ ++ Sbjct: 370 LDLNSELSQALLRLEKENQNLRERLQGLSGETPDPKNKGQHVQTEGEQGRNSKVQIMTVH 429 Query: 383 --KSPWSQLSSETLNQDT---DKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXX 437 +SP Q S ++ Q+ + + K ++ + + I SL + L +K+ E Sbjct: 430 LEESPLEQKSCDSYWQEKVSCETEALKRQLEESALEIDSLKRQLKEKQ---DEAQNQQNQ 486 Query: 438 XXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVN 497 K+ L +LQ ++ + + + + E ++E+L+ + + +K + Sbjct: 487 LSESTTEKNALQRKLQGNAEEILSLQKQLD-----KSIKECHLLKEELQGMVKESLK-MQ 540 Query: 498 VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQ---KTID----NFSKV 550 D E++++ + ++ + ++EI + + + + +L KQ++ K ++ N ++ Sbjct: 541 HHDGNEEMQTQKRKVEESSEEILSLQRQLQDIVKKEELLQKQLEISDKMVETQHRNLAER 600 Query: 551 SDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAE 610 S+ +++ +T E+ L +++ E E+EK Q HL + ++E E L + Sbjct: 601 SEEIRQLQEITGEVQSLKRQLEETEKEKQCQQRHL-------------QESVLEAEELQK 647 Query: 611 TRLKAISL--LESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVH----- 663 LKA+ LE+Q + +E+ L ++ E D A QLQ + S K + Sbjct: 648 QLLKALESKELETQLKESAKEIQSLGKQLKESRDAEALRRQLQEREEQSFKKQLQDNAEK 707 Query: 664 ---LEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDL 720 L+ Q++ +A + + + ++ L G +++ D + +L+ +E L Sbjct: 708 IQSLKNQLNESTAENISHEMQLTERECLEKSLKGQLEERNVDINSLQKQLEKKTEEEKSL 767 Query: 721 TDKLEKMSAEK-ISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIE---SELSKYKS 776 +LE+ EK + ++ + N +E ++ Q I+ + + L + E+ K Sbjct: 768 KRRLEENEREKQVQQIHLESNLKEVQSLKKQNQIEEREKMEQLLKREWQVSAEEVQVLKQ 827 Query: 777 RICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQ--------EDELVNRLA 828 ++ +E++ E L + D + L EK K + TIQ E+E+ Sbjct: 828 QLNDKQENLEEKESLLRQLLQTNDSMKRQLDEKSKHVEDLTIQFQKNLKDCEEEIQTLKW 887 Query: 829 VLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDL 888 L D + ++ Q + +E + + L+E + +Q +++ +K TD+ Sbjct: 888 KLTDSNNELQSQKIMLERNKETEDSLKRKLVERSDEIQSLKRHLEEAKGQYQKKQEYTDM 947 Query: 889 AESESTKYQT--QLRDLESNLKRITHEHQTLIVQKKK---EIEDLEIEFNTQIESAIRDK 943 +S + +L L+ L+ T E Q+L+ Q ++ EI+ ++ +F E K Sbjct: 948 KDSPQGQANDLGELHTLKRQLQESTEEMQSLMRQLEESAAEIQTVKRQFQESAEKIQLQK 1007 Query: 944 KVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQ----QTQ 999 + L + +++ QL +LQE N IE L ++E + +E +++ +Q+ + Q Sbjct: 1008 RQLEDSVGESLSLKRQL-GELQESNNKIETLQRQLQE-REDEIETLERKLQESADEVELQ 1065 Query: 1000 SPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLEN 1059 E + + + A ++ + + ++ Q+ + S L + + Sbjct: 1066 KKQLAEMELQGVRRERAEIQGRYDSLLKDLQRQEGDLERAQRELRRNRSALRILRQEHQE 1125 Query: 1060 MEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKE--LKETKLTFEMNIPKTEGMIISST 1117 ++E ++S Q +Q +EL+ V+EQ+ I E L+ L E + K E + T Sbjct: 1126 LQERFSQLSVQ---GEQTQQELKRKVQEQEGTIHESQLENQNLQEEQHRLKEELSHLDKT 1182 Query: 1118 IEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKL---NTELQECYTK 1174 +E S D + + +E+++ +ER L+EQ +L NT L E Sbjct: 1183 LEERSLDLREMKKQLGT--------EHREKDQLERERGELREQVQRLEISNTALTEQCQV 1234 Query: 1175 IIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLL 1214 + Q++ + Q+Q N L S++ L+ +N LL Sbjct: 1235 LSQVK----------LTIQDQNNLLLSQIHSLSRDNRELL 1264 Score = 104 bits (250), Expect = 2e-20 Identities = 190/987 (19%), Positives = 424/987 (42%), Gaps = 62/987 (6%) Query: 625 DLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLE-EQIDALSASKKELALVIE 683 DL +L +Q+ +E ++L D +Q + + +E++ +H + ++ A++A + ++ Sbjct: 177 DLQSKLRRARQELEEKGEELLD-NQQHVEMLEAELRKLHQQVRELSAMAALSRGYRDELD 235 Query: 684 NLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEE 743 L+ + + L N+K M Q +QE + + L + +L A+ E Sbjct: 236 ALRERSRRAEAQVNAL-NEKLRTMEIFQRSLQEEKEFSRALLEDKEVLEHQLAAERERSE 294 Query: 744 QSKI--QTQFGIDAKIQ----ERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLER 797 + ++ + + ++ +IQ ERD + ++ L + EE + E+ + ER Sbjct: 295 KLRLCEKEKHSLEERIQRLEMERDSECQRVQFLLH---DNLTLAEEVRVLREETQRGWER 351 Query: 798 KADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQI 857 + G + ++ + EL L L ++ + ++L + E + + K Q Sbjct: 352 VYESHGDTVPVWEREQDVLDLNS-ELSQALLRLEKENQNLRERLQGLSGETPDPKNKGQH 410 Query: 858 LL---EENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEH 914 + E+ +N ++ + + + L +K+ + E S + + R LE + I Sbjct: 411 VQTEGEQGRNSKVQIMTVHLEESPLEQKSCDSYWQEKVSCETEALKRQLEESALEI---- 466 Query: 915 QTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNI--- 971 +L Q K++ ++ + + N Q+ + +K L K + N E + L+ QL + Sbjct: 467 DSLKRQLKEKQDEAQNQQN-QLSESTTEKNALQRKLQGNAEEILSLQKQLDKSIKECHLL 525 Query: 972 -ENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKD--EEIIAL 1028 E L V+E KM ++ +Q Q+ + + +E+ ++ +L ++K+++ ++ + + Sbjct: 526 KEELQGMVKESLKMQHHDGNEEMQTQKRKVEESSEEILSLQRQLQDIVKKEELLQKQLEI 585 Query: 1029 NQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQ 1088 + K+ Q ++ S+ +L + T ++++++ +++ K+ ++H +E + E Sbjct: 586 SDKMVETQHRNLAERSEEIRQLQEITGEVQSLKRQLEETEKEKQCQQRHLQESVLEAEEL 645 Query: 1089 DDQI-KELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEE 1147 Q+ K L+ +L ++ E + ++ S DA + ++Q+ Sbjct: 646 QKQLLKALESKELETQLKESAKEIQSLGKQLKE-SRDAEALRRQLQEREEQSFKKQLQDN 704 Query: 1148 EEFIQE-RSVLQEQSAK-LNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQ 1205 E IQ ++ L E +A+ ++ E+Q + + E L L G IN L+ +LE+ Sbjct: 705 AEKIQSLKNQLNESTAENISHEMQ-----LTERECLEKSLKGQLEERNVDINSLQKQLEK 759 Query: 1206 LNTENDNLLSTVAE--LRSSISSA-VDQRGFEIAELWKQH-LAQREADFQKTEHELRVQL 1261 E +L + E + ++ E+ L KQ+ + +RE Q + E +V Sbjct: 760 KTEEEKSLKRRLEENEREKQVQQIHLESNLKEVQSLKKQNQIEEREKMEQLLKREWQVSA 819 Query: 1262 SAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIE 1321 + +QL D ++ ++E+ ++ S++ +L +K +H+ +L ++ + E Sbjct: 820 EEVQVLKQQLNDKQENLEEKESLLRQLLQTNDSMKRQLDEKSKHVEDLTIQFQKNLKDCE 879 Query: 1322 ILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSS 1381 EI+ K + TE+ +++ E+S I L+++ Sbjct: 880 ---EEIQTLKWKLTDSNNELQSQKIMLERNKETEDSLKRKLVERSD-EIQSLKRHLEEAK 935 Query: 1382 XXXXXXXXXXXXRVN-DAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQ 1440 + + +A L H L+ + E ++ L + E + V++Q Sbjct: 936 GQYQKKQEYTDMKDSPQGQANDLGELHTLKRQLQESTEEMQSLMRQLEESAAEIQTVKRQ 995 Query: 1441 LVEYEKRIEDLTYEKESELA-ILRLK-----MHENANHYETMQKESEIERVKLIEELNVK 1494 E ++I+ + E + L LK + E+ N ET+Q++ + ER IE L K Sbjct: 996 FQESAEKIQLQKRQLEDSVGESLSLKRQLGELQESNNKIETLQRQLQ-EREDEIETLERK 1054 Query: 1495 ITES---VSL-NKQVAELN-KALEEEVA----KTNEMQTALENQEIEIVTLNDEITNLQN 1545 + ES V L KQ+AE+ + + E A + + + L+ QE ++ E+ ++ Sbjct: 1055 LQESADEVELQKKQLAEMELQGVRRERAEIQGRYDSLLKDLQRQEGDLERAQRELRRNRS 1114 Query: 1546 MVRASSSKIQK-HVSFASDTKQGRDEQ 1571 +R + Q+ F+ + QG Q Sbjct: 1115 ALRILRQEHQELQERFSQLSVQGEQTQ 1141 Score = 97.1 bits (231), Expect = 4e-18 Identities = 152/781 (19%), Positives = 336/781 (43%), Gaps = 71/781 (9%) Query: 147 LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXX 206 L + +K+++ L++ K++ET +L E+ E Q+ E + + Sbjct: 569 LQDIVKKEELLQKQLEISDKMVETQHRNLAERSEEIRQLQEITGEVQSLKRQLEET---- 624 Query: 207 XXXXXEDTKQ-QMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAAR- 264 E KQ Q +QE+ +EAE + +++LLK +ESK++ E A ++ + Sbjct: 625 -----EKEKQCQQRHLQES--VLEAE--ELQKQLLKALESKELETQLKESAKEIQSLGKQ 675 Query: 265 FEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTEL 324 + S + L ++L++ QS++ E T +++ L Sbjct: 676 LKESRDAEALRRQLQEREEQSFKKQLQDNAEKIQSLKNQLNESTAENISHEMQLTERECL 735 Query: 325 TKKIE-LLEHLNCQIRQTNKELENKL-ATMGTESKAVSSPSKKGSPLISRKSGRNTASKM 382 K ++ LE N I K+LE K + + + +K I +S + Sbjct: 736 EKSLKGQLEERNVDINSLQKQLEKKTEEEKSLKRRLEENEREKQVQQIHLESNLKEVQSL 795 Query: 383 KSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXX 442 K ++ ++ +++ K E +Q L + L DK+ + EK++ Sbjct: 796 KK-----QNQIEEREKMEQLLKREWQVSAEEVQVLKQQLNDKQENLEEKESLLRQLLQT- 849 Query: 443 XGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLI 502 D++ QL E +H+E + I N +D E + + + N+E++ + K ++ Sbjct: 850 --NDSMKRQLD-EKSKHVEDLT-IQFQKNLKDCEEEIQTLKWKLTDSNNELQ--SQKIML 903 Query: 503 EKLKSAEE----QITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIV 558 E+ K E+ ++ + +DEI + +++ + K ++ K ++ + DS + Sbjct: 904 ERNKETEDSLKRKLVERSDEIQSLKRHLEEAKGQYQKK--------QEYTDMKDSPQGQA 955 Query: 559 RLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISL 618 ELH L +++ E EE +L L +S I++ V ++ E + + + + Sbjct: 956 NDLGELHTLKRQLQESTEEMQSLMRQL--EESAAEIQT-VKRQFQESAEKIQLQKRQLED 1012 Query: 619 LESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKEL 678 + L ++L LQ+ +++E + Q + D++ E L+E D + KK+L Sbjct: 1013 SVGESLSLKRQLGELQESNNKIETLQRQL-QEREDEI--ETLERKLQESADEVELQKKQL 1069 Query: 679 A-LVIENLKLDKEQLYG----TIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKIS 733 A + ++ ++ ++ ++ G +KDL+ + D + + Q ++ N ++ + +++ Sbjct: 1070 AEMELQGVRRERAEIQGRYDSLLKDLQRQEGD-LERAQRELRRNRSAL-RILRQEHQELQ 1127 Query: 734 ELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIA----VME 789 E ++++ + + QTQ + K+QE++ I + E + RL+E ++ +E Sbjct: 1128 ERFSQLSVQGE---QTQQELKRKVQEQEGTIHESQLENQNLQEEQHRLKEELSHLDKTLE 1184 Query: 790 DRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENK 849 +R L QLG+ +EK + E EL ++ L + + +Q + Sbjct: 1185 ERSLDLREMKKQLGTEHREKDQLERE----RGELREQVQRLEISNTALTEQCQVLSQVKL 1240 Query: 850 ELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKR 909 +Q +N +LL + +L + + L +L + E +Y+ +L +L+ ++ Sbjct: 1241 TIQDQNNLLLSQIHSLS------RDNRELLERSLQSGELRQEEERRYREKLTELKHEKQK 1294 Query: 910 I 910 + Sbjct: 1295 L 1295 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.307 0.124 0.316 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 1,400,727,827 Number of Sequences: 1657284 Number of extensions: 55665598 Number of successful extensions: 564145 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 1450 Number of HSP's successfully gapped in prelim test: 15877 Number of HSP's that attempted gapping in prelim test: 358721 Number of HSP's gapped (non-prelim): 119830 length of query: 1630 length of database: 575,637,011 effective HSP length: 111 effective length of query: 1519 effective length of database: 391,678,487 effective search space: 594959621753 effective search space used: 594959621753 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 42 (21.6 bits) S2: 79 (35.9 bits)
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