SilkBase IMG001 IMG002 IMG003 IMG005 IMG006 IMG007 IMG008 IMG009 kuwako IMG010 IMG011 IMG012

Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA000894-TA|BGIBMGA000894-PA|IPR000308|14-3-3 protein,
IPR010989|t-snare, IPR009054|DNA topoisomerases I, dispensable insert,
eukaryotic-type, IPR009053|Prefoldin
         (1630 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_UPI0000D55C9F Cluster: PREDICTED: similar to Golgin sub...   251   1e-64
UniRef50_Q171W5 Cluster: Lava lamp protein; n=2; Culicidae|Rep: ...   236   3e-60
UniRef50_A2DLG0 Cluster: Viral A-type inclusion protein, putativ...   234   2e-59
UniRef50_A2DGN0 Cluster: Viral A-type inclusion protein, putativ...   232   7e-59
UniRef50_UPI000049A29E Cluster: Viral A-type inclusion protein r...   214   2e-53
UniRef50_A2FD36 Cluster: Viral A-type inclusion protein, putativ...   210   2e-52
UniRef50_A2E8Z5 Cluster: Viral A-type inclusion protein, putativ...   209   6e-52
UniRef50_Q24HK7 Cluster: Viral A-type inclusion protein repeat c...   208   1e-51
UniRef50_A2DD37 Cluster: Viral A-type inclusion protein, putativ...   206   5e-51
UniRef50_A2F531 Cluster: Viral A-type inclusion protein, putativ...   205   7e-51
UniRef50_A2EMR6 Cluster: Viral A-type inclusion protein, putativ...   204   2e-50
UniRef50_A0CPG2 Cluster: Chromosome undetermined scaffold_23, wh...   200   3e-49
UniRef50_UPI00015B5D72 Cluster: PREDICTED: similar to viral A-ty...   197   2e-48
UniRef50_A2EYA1 Cluster: Viral A-type inclusion protein, putativ...   197   2e-48
UniRef50_A7TQ63 Cluster: Putative uncharacterized protein; n=1; ...   197   2e-48
UniRef50_A2FSZ8 Cluster: Viral A-type inclusion protein, putativ...   196   3e-48
UniRef50_A2EN31 Cluster: Viral A-type inclusion protein, putativ...   196   3e-48
UniRef50_A2DDX5 Cluster: Viral A-type inclusion protein, putativ...   196   3e-48
UniRef50_Q23DH8 Cluster: DNA-directed RNA polymerase, omega subu...   196   4e-48
UniRef50_Q54G05 Cluster: Putative uncharacterized protein; n=1; ...   195   1e-47
UniRef50_A2DDP2 Cluster: Viral A-type inclusion protein, putativ...   194   2e-47
UniRef50_UPI0000DB6B83 Cluster: PREDICTED: similar to lava lamp ...   193   3e-47
UniRef50_A0BMM9 Cluster: Chromosome undetermined scaffold_117, w...   192   9e-47
UniRef50_A2E8H6 Cluster: Viral A-type inclusion protein, putativ...   188   1e-45
UniRef50_Q234R7 Cluster: Viral A-type inclusion protein repeat c...   188   1e-45
UniRef50_A2EZ87 Cluster: Viral A-type inclusion protein, putativ...   187   3e-45
UniRef50_UPI00006CDA45 Cluster: hypothetical protein TTHERM_0040...   186   3e-45
UniRef50_A2DKE3 Cluster: Viral A-type inclusion protein, putativ...   186   3e-45
UniRef50_Q22AT3 Cluster: Viral A-type inclusion protein repeat c...   186   6e-45
UniRef50_UPI0000D8E0D3 Cluster: UPI0000D8E0D3 related cluster; n...   185   1e-44
UniRef50_UPI00006CB2DA Cluster: Viral A-type inclusion protein r...   184   1e-44
UniRef50_UPI0000D8E0D4 Cluster: UPI0000D8E0D4 related cluster; n...   184   1e-44
UniRef50_A2FQ07 Cluster: Viral A-type inclusion protein, putativ...   184   2e-44
UniRef50_UPI00006CE95F Cluster: Viral A-type inclusion protein r...   181   1e-43
UniRef50_Q22RF4 Cluster: Viral A-type inclusion protein repeat c...   181   1e-43
UniRef50_A2DA80 Cluster: Viral A-type inclusion protein, putativ...   180   4e-43
UniRef50_A2FQ08 Cluster: Viral A-type inclusion protein, putativ...   179   7e-43
UniRef50_A2DKP8 Cluster: Viral A-type inclusion protein, putativ...   178   9e-43
UniRef50_A2ETW9 Cluster: Viral A-type inclusion protein, putativ...   177   2e-42
UniRef50_Q237L2 Cluster: Kinesin motor domain containing protein...   177   3e-42
UniRef50_A2EVM3 Cluster: Viral A-type inclusion protein, putativ...   175   6e-42
UniRef50_A2ERL6 Cluster: Viral A-type inclusion protein, putativ...   175   8e-42
UniRef50_Q23QC3 Cluster: Viral A-type inclusion protein repeat c...   175   1e-41
UniRef50_A2EZE6 Cluster: Viral A-type inclusion protein, putativ...   175   1e-41
UniRef50_A2FKT9 Cluster: Viral A-type inclusion protein, putativ...   174   1e-41
UniRef50_UPI00006CF26E Cluster: Viral A-type inclusion protein r...   172   6e-41
UniRef50_UPI00006CD2DD Cluster: Viral A-type inclusion protein r...   172   6e-41
UniRef50_A2FX23 Cluster: Formin Homology 2 Domain containing pro...   172   6e-41
UniRef50_A0CWJ6 Cluster: Chromosome undetermined scaffold_3, who...   172   6e-41
UniRef50_UPI00015A55AB Cluster: UPI00015A55AB related cluster; n...   172   8e-41
UniRef50_UPI00006CD140 Cluster: Viral A-type inclusion protein r...   170   2e-40
UniRef50_A2FKU0 Cluster: Viral A-type inclusion protein, putativ...   170   2e-40
UniRef50_UPI00006CD895 Cluster: hypothetical protein TTHERM_0052...   170   3e-40
UniRef50_A0CKK3 Cluster: Chromosome undetermined scaffold_2, who...   170   3e-40
UniRef50_A2FK27 Cluster: Viral A-type inclusion protein, putativ...   169   4e-40
UniRef50_A2F3I9 Cluster: Viral A-type inclusion protein, putativ...   169   4e-40
UniRef50_UPI00006CB352 Cluster: Viral A-type inclusion protein r...   169   5e-40
UniRef50_A2EJ43 Cluster: Viral A-type inclusion protein, putativ...   167   2e-39
UniRef50_A0DJQ4 Cluster: Chromosome undetermined scaffold_53, wh...   166   4e-39
UniRef50_A0BIQ2 Cluster: Chromosome undetermined scaffold_11, wh...   166   5e-39
UniRef50_A0DXX1 Cluster: Chromosome undetermined scaffold_69, wh...   165   7e-39
UniRef50_UPI00006CA483 Cluster: hypothetical protein TTHERM_0049...   165   1e-38
UniRef50_Q4LE75 Cluster: CENPE variant protein; n=9; Euteleostom...   165   1e-38
UniRef50_Q231C5 Cluster: Putative uncharacterized protein; n=1; ...   162   6e-38
UniRef50_Q6FWE0 Cluster: Candida glabrata strain CBS138 chromoso...   162   6e-38
UniRef50_A0CWT0 Cluster: Chromosome undetermined scaffold_3, who...   161   1e-37
UniRef50_A0CZI7 Cluster: Chromosome undetermined scaffold_32, wh...   160   3e-37
UniRef50_Q59K46 Cluster: Likely vesicular transport factor Uso1p...   160   3e-37
UniRef50_A0DBC2 Cluster: Chromosome undetermined scaffold_44, wh...   160   3e-37
UniRef50_A0DWU7 Cluster: Chromosome undetermined scaffold_67, wh...   159   4e-37
UniRef50_UPI0000F1EC3A Cluster: PREDICTED: hypothetical protein;...   158   1e-36
UniRef50_Q9FJ35 Cluster: Myosin heavy chain-like protein; n=2; A...   158   1e-36
UniRef50_A2EUG5 Cluster: Putative uncharacterized protein; n=3; ...   158   1e-36
UniRef50_A2DNX6 Cluster: Viral A-type inclusion protein, putativ...   158   1e-36
UniRef50_A0C3N5 Cluster: Chromosome undetermined scaffold_147, w...   158   1e-36
UniRef50_A2EPG1 Cluster: Viral A-type inclusion protein, putativ...   157   2e-36
UniRef50_UPI00006CC2B2 Cluster: hypothetical protein TTHERM_0066...   157   2e-36
UniRef50_A2F8N3 Cluster: Viral A-type inclusion protein, putativ...   157   2e-36
UniRef50_A0EHN8 Cluster: Chromosome undetermined scaffold_97, wh...   157   2e-36
UniRef50_Q02224 Cluster: Centromeric protein E; n=8; Eutheria|Re...   157   2e-36
UniRef50_Q23D13 Cluster: Viral A-type inclusion protein repeat c...   157   3e-36
UniRef50_UPI000065DFDD Cluster: Homolog of Homo sapiens "Centrom...   155   7e-36
UniRef50_Q22SA1 Cluster: Putative uncharacterized protein; n=1; ...   153   3e-35
UniRef50_A0DZ20 Cluster: Chromosome undetermined scaffold_7, who...   153   4e-35
UniRef50_A0CWC7 Cluster: Chromosome undetermined scaffold_3, who...   153   4e-35
UniRef50_A0DR95 Cluster: Chromosome undetermined scaffold_60, wh...   153   5e-35
UniRef50_Q6C359 Cluster: Similar to DEHA0C09658g Debaryomyces ha...   153   5e-35
UniRef50_UPI0000F2140F Cluster: PREDICTED: similar to nuclear mi...   152   7e-35
UniRef50_UPI0000E7FDD2 Cluster: PREDICTED: similar to trans-Golg...   152   9e-35
UniRef50_A2FU34 Cluster: Putative uncharacterized protein; n=1; ...   151   1e-34
UniRef50_A0BRG1 Cluster: Chromosome undetermined scaffold_122, w...   150   4e-34
UniRef50_Q4RQ56 Cluster: Chromosome 17 SCAF15006, whole genome s...   149   5e-34
UniRef50_UPI0000498399 Cluster: Viral A-type inclusion protein r...   149   6e-34
UniRef50_A2DGH5 Cluster: Viral A-type inclusion protein, putativ...   149   8e-34
UniRef50_UPI0000D565C6 Cluster: PREDICTED: similar to CG3493-PA;...   148   1e-33
UniRef50_UPI00015A607A Cluster: UPI00015A607A related cluster; n...   148   1e-33
UniRef50_O76329 Cluster: Interaptin; n=2; Dictyostelium discoide...   147   2e-33
UniRef50_A0DDW1 Cluster: Chromosome undetermined scaffold_47, wh...   147   2e-33
UniRef50_Q22RB5 Cluster: Putative uncharacterized protein; n=1; ...   147   3e-33
UniRef50_Q13439 Cluster: Golgin subfamily A member 4; n=34; Tetr...   147   3e-33
UniRef50_Q25893 Cluster: Liver stage antigen; n=41; Plasmodium f...   146   4e-33
UniRef50_Q2NJC3 Cluster: Putative uncharacterized protein; n=1; ...   145   8e-33
UniRef50_A0DBE4 Cluster: Chromosome undetermined scaffold_44, wh...   145   8e-33
UniRef50_Q6BUQ9 Cluster: Similar to sp|P25386 Saccharomyces cere...   145   8e-33
UniRef50_UPI000150A61D Cluster: hypothetical protein TTHERM_0037...   144   1e-32
UniRef50_Q1FIV0 Cluster: Putative uncharacterized protein; n=1; ...   144   2e-32
UniRef50_A2FVB6 Cluster: Putative uncharacterized protein; n=2; ...   144   2e-32
UniRef50_A0BUU6 Cluster: Chromosome undetermined scaffold_13, wh...   144   2e-32
UniRef50_UPI0000499259 Cluster: hypothetical protein 388.t00006;...   144   2e-32
UniRef50_Q10411 Cluster: Sporulation-specific protein 15; n=1; S...   144   2e-32
UniRef50_A0CQM3 Cluster: Chromosome undetermined scaffold_24, wh...   143   3e-32
UniRef50_Q86KX8 Cluster: Similar to Dictyostelium discoideum (Sl...   143   4e-32
UniRef50_A0DQ77 Cluster: Chromosome undetermined scaffold_6, who...   143   4e-32
UniRef50_UPI00006CC010 Cluster: hypothetical protein TTHERM_0041...   142   5e-32
UniRef50_UPI00015A6057 Cluster: UPI00015A6057 related cluster; n...   142   5e-32
UniRef50_A2DZ81 Cluster: Viral A-type inclusion protein, putativ...   142   5e-32
UniRef50_Q23PQ6 Cluster: Putative uncharacterized protein; n=1; ...   142   9e-32
UniRef50_A0CPT0 Cluster: Chromosome undetermined scaffold_23, wh...   142   9e-32
UniRef50_A2FP55 Cluster: Viral A-type inclusion protein, putativ...   141   1e-31
UniRef50_A0EEL6 Cluster: Chromosome undetermined scaffold_91, wh...   141   1e-31
UniRef50_Q2NHV1 Cluster: Putative uncharacterized protein; n=1; ...   141   2e-31
UniRef50_A0DKF0 Cluster: Chromosome undetermined scaffold_54, wh...   140   3e-31
UniRef50_Q9VJE5 Cluster: Restin homolog; n=4; Drosophila melanog...   140   3e-31
UniRef50_A0D7Y2 Cluster: Chromosome undetermined scaffold_40, wh...   140   4e-31
UniRef50_Q23DA0 Cluster: Putative uncharacterized protein; n=1; ...   139   5e-31
UniRef50_UPI0000F2D5B2 Cluster: PREDICTED: similar to centromere...   139   7e-31
UniRef50_UPI00004995B4 Cluster: myosin heavy chain; n=1; Entamoe...   139   7e-31
UniRef50_P25386 Cluster: Intracellular protein transport protein...   139   7e-31
UniRef50_A2ESM9 Cluster: Putative uncharacterized protein; n=1; ...   138   9e-31
UniRef50_UPI0000F1FE72 Cluster: PREDICTED: hypothetical protein;...   138   1e-30
UniRef50_UPI00006CFFCF Cluster: hypothetical protein TTHERM_0075...   138   1e-30
UniRef50_Q22W02 Cluster: Putative uncharacterized protein; n=1; ...   138   2e-30
UniRef50_A0EHS3 Cluster: Chromosome undetermined scaffold_97, wh...   138   2e-30
UniRef50_A0D3I1 Cluster: Chromosome undetermined scaffold_36, wh...   137   2e-30
UniRef50_Q4RT41 Cluster: Chromosome 12 SCAF14999, whole genome s...   137   3e-30
UniRef50_A0DQH1 Cluster: Chromosome undetermined scaffold_6, who...   137   3e-30
UniRef50_A0DI28 Cluster: Chromosome undetermined scaffold_51, wh...   136   4e-30
UniRef50_A0CUZ8 Cluster: Chromosome undetermined scaffold_29, wh...   136   4e-30
UniRef50_UPI0000E476CA Cluster: PREDICTED: similar to KIAA0445 p...   136   5e-30
UniRef50_Q23QE6 Cluster: Guanylate-binding protein, N-terminal d...   136   5e-30
UniRef50_UPI00006615CF Cluster: Homolog of Homo sapiens "Golgi a...   136   6e-30
UniRef50_Q4T928 Cluster: Chromosome undetermined SCAF7646, whole...   135   8e-30
UniRef50_A2ERV4 Cluster: Putative uncharacterized protein; n=1; ...   135   8e-30
UniRef50_Q7SHZ4 Cluster: Putative uncharacterized protein NCU006...   135   8e-30
UniRef50_Q8MSS1 Cluster: Protein lava lamp; n=1; Drosophila mela...   135   8e-30
UniRef50_A0CKT9 Cluster: Chromosome undetermined scaffold_20, wh...   135   1e-29
UniRef50_A0CCF8 Cluster: Chromosome undetermined scaffold_167, w...   135   1e-29
UniRef50_UPI00006CD8D3 Cluster: hypothetical protein TTHERM_0052...   134   1e-29
UniRef50_A0EEQ9 Cluster: Chromosome undetermined scaffold_92, wh...   134   1e-29
UniRef50_Q3V6T2 Cluster: Girdin; n=53; Euteleostomi|Rep: Girdin ...   134   1e-29
UniRef50_Q4N897 Cluster: Putative uncharacterized protein; n=2; ...   134   2e-29
UniRef50_A2ESN0 Cluster: Viral A-type inclusion protein, putativ...   134   2e-29
UniRef50_A0CFL4 Cluster: Chromosome undetermined scaffold_176, w...   134   2e-29
UniRef50_Q22NP6 Cluster: Putative uncharacterized protein; n=1; ...   134   3e-29
UniRef50_A0CUE6 Cluster: Chromosome undetermined scaffold_28, wh...   134   3e-29
UniRef50_UPI00006CB2D6 Cluster: Viral A-type inclusion protein r...   133   4e-29
UniRef50_A0DDB5 Cluster: Chromosome undetermined scaffold_46, wh...   133   4e-29
UniRef50_A0CZE8 Cluster: Chromosome undetermined scaffold_32, wh...   133   4e-29
UniRef50_A5DLM2 Cluster: Putative uncharacterized protein; n=1; ...   133   4e-29
UniRef50_A0DAF7 Cluster: Chromosome undetermined scaffold_43, wh...   132   6e-29
UniRef50_Q6CPF6 Cluster: Kluyveromyces lactis strain NRRL Y-1140...   132   6e-29
UniRef50_UPI0000E48979 Cluster: PREDICTED: similar to kinesin-re...   132   8e-29
UniRef50_A2DUI3 Cluster: Viral A-type inclusion protein, putativ...   132   8e-29
UniRef50_A0D2T6 Cluster: Chromosome undetermined scaffold_35, wh...   132   8e-29
UniRef50_UPI0000E47346 Cluster: PREDICTED: similar to Golgi-asso...   132   1e-28
UniRef50_Q8IBY8 Cluster: Putative uncharacterized protein PF07_0...   132   1e-28
UniRef50_Q7RGY2 Cluster: Repeat organellar protein-related; n=3;...   132   1e-28
UniRef50_Q54NP8 Cluster: Kinesin 4; n=3; Dictyostelium discoideu...   132   1e-28
UniRef50_A2DLG1 Cluster: Viral A-type inclusion protein, putativ...   132   1e-28
UniRef50_UPI00006CA4F0 Cluster: Viral A-type inclusion protein r...   131   1e-28
UniRef50_Q4Q3D8 Cluster: Putative uncharacterized protein; n=3; ...   131   1e-28
UniRef50_O96133 Cluster: Putative uncharacterized protein PFB014...   131   1e-28
UniRef50_Q15075 Cluster: Early endosome antigen 1; n=30; Euteleo...   131   1e-28
UniRef50_Q09EF7 Cluster: Putative uncharacterized protein; n=8; ...   131   2e-28
UniRef50_A0CGX1 Cluster: Chromosome undetermined scaffold_18, wh...   131   2e-28
UniRef50_A0BCM0 Cluster: Chromosome undetermined scaffold_10, wh...   131   2e-28
UniRef50_Q22AS4 Cluster: Putative uncharacterized protein; n=1; ...   130   2e-28
UniRef50_A2F8N8 Cluster: Putative uncharacterized protein; n=2; ...   130   2e-28
UniRef50_Q6RT24 Cluster: Centromere associated protein-E; n=13; ...   130   3e-28
UniRef50_Q9BJD3 Cluster: Major plasmodial myosin heavy chain; n=...   130   3e-28
UniRef50_A0ECU5 Cluster: Chromosome undetermined scaffold_9, who...   130   3e-28
UniRef50_A0BTE2 Cluster: Chromosome undetermined scaffold_127, w...   130   4e-28
UniRef50_Q7RIN9 Cluster: Putative uncharacterized protein PY0357...   129   5e-28
UniRef50_UPI00006A154D Cluster: Centrosomal protein 2 (Centrosom...   129   7e-28
UniRef50_A0D4Y2 Cluster: Chromosome undetermined scaffold_38, wh...   129   7e-28
UniRef50_Q23E34 Cluster: Putative uncharacterized protein; n=2; ...   128   9e-28
UniRef50_UPI00006CCC54 Cluster: hypothetical protein TTHERM_0033...   128   1e-27
UniRef50_A4S4A9 Cluster: Predicted protein; n=2; Viridiplantae|R...   128   1e-27
UniRef50_UPI0000D57874 Cluster: PREDICTED: similar to GRIP and c...   128   2e-27
UniRef50_Q23KF2 Cluster: Putative uncharacterized protein; n=1; ...   128   2e-27
UniRef50_Q16FM5 Cluster: LL5 beta protein, putative; n=2; Aedes ...   128   2e-27
UniRef50_A0BIX7 Cluster: Chromosome undetermined scaffold_11, wh...   128   2e-27
UniRef50_A0NCN7 Cluster: ENSANGP00000031886; n=1; Anopheles gamb...   127   2e-27
UniRef50_A2DGV9 Cluster: Viral A-type inclusion protein, putativ...   127   3e-27
UniRef50_A0DR44 Cluster: Chromosome undetermined scaffold_6, who...   127   3e-27
UniRef50_UPI00006CB6DE Cluster: hypothetical protein TTHERM_0049...   126   4e-27
UniRef50_Q52L24 Cluster: LOC733209 protein; n=1; Xenopus laevis|...   126   4e-27
UniRef50_Q7NBF8 Cluster: Putative uncharacterized protein; n=1; ...   126   4e-27
UniRef50_Q16IF0 Cluster: Condensin, SMC5-subunit, putative; n=1;...   126   4e-27
UniRef50_A0E6F4 Cluster: Chromosome undetermined scaffold_8, who...   126   4e-27
UniRef50_A7DN60 Cluster: Chromosome segregation ATPase-like prot...   126   4e-27
UniRef50_A0DA04 Cluster: Chromosome undetermined scaffold_42, wh...   126   5e-27
UniRef50_A0CJD5 Cluster: Chromosome undetermined scaffold_2, who...   126   5e-27
UniRef50_O61308 Cluster: 227 kDa spindle- and centromere-associa...   126   5e-27
UniRef50_Q8IWJ2 Cluster: GRIP and coiled-coil domain-containing ...   126   5e-27
UniRef50_Q245H6 Cluster: Putative uncharacterized protein; n=1; ...   126   7e-27
UniRef50_Q22TK4 Cluster: Putative uncharacterized protein; n=1; ...   126   7e-27
UniRef50_A0CFQ2 Cluster: Chromosome undetermined scaffold_177, w...   126   7e-27
UniRef50_A0BYX7 Cluster: Chromosome undetermined scaffold_138, w...   126   7e-27
UniRef50_UPI00015B5164 Cluster: PREDICTED: similar to ENSANGP000...   125   9e-27
UniRef50_UPI00006CB7E3 Cluster: Viral A-type inclusion protein r...   125   9e-27
UniRef50_O42263 Cluster: Kinesin-related protein; n=2; Xenopus|R...   125   9e-27
UniRef50_A2D7K4 Cluster: Putative uncharacterized protein; n=1; ...   125   9e-27
UniRef50_Q4D6G7 Cluster: Putative uncharacterized protein; n=4; ...   125   1e-26
UniRef50_Q23Q31 Cluster: Viral A-type inclusion protein repeat c...   125   1e-26
UniRef50_P49454 Cluster: Centromere protein F; n=15; Eutheria|Re...   125   1e-26
UniRef50_UPI0001509DA0 Cluster: hypothetical protein TTHERM_0053...   124   2e-26
UniRef50_UPI00006CC401 Cluster: hypothetical protein TTHERM_0013...   124   2e-26
UniRef50_UPI00006CAB41 Cluster: hypothetical protein TTHERM_0078...   124   2e-26
UniRef50_Q22CJ7 Cluster: Putative uncharacterized protein; n=1; ...   124   2e-26
UniRef50_UPI00006CD102 Cluster: Kinesin motor domain containing ...   124   2e-26
UniRef50_Q9XZE3 Cluster: Myosin heavy chain; n=1; Amoeba proteus...   124   2e-26
UniRef50_Q24GP7 Cluster: Putative uncharacterized protein; n=2; ...   124   2e-26
UniRef50_A0CVZ5 Cluster: Chromosome undetermined scaffold_3, who...   124   2e-26
UniRef50_P75471 Cluster: Cytadherence high molecular weight prot...   124   2e-26
UniRef50_A5DD85 Cluster: Putative uncharacterized protein; n=1; ...   124   3e-26
UniRef50_UPI000051A547 Cluster: PREDICTED: similar to CG6129-PB,...   123   4e-26
UniRef50_UPI0000ECA83C Cluster: Centrosome-associated protein CE...   123   4e-26
UniRef50_Q57UD0 Cluster: Kinesin K39, putative; n=1; Trypanosoma...   123   4e-26
UniRef50_Q4E572 Cluster: Antigenic protein, putative; n=2; Trypa...   123   4e-26
UniRef50_A3LZ88 Cluster: Myosin-1; n=1; Pichia stipitis|Rep: Myo...   123   4e-26
UniRef50_Q54JG6 Cluster: Putative uncharacterized protein; n=1; ...   123   5e-26
UniRef50_Q22AQ6 Cluster: Putative uncharacterized protein; n=1; ...   123   5e-26
UniRef50_A2EJ44 Cluster: Viral A-type inclusion protein, putativ...   123   5e-26
UniRef50_A0DV70 Cluster: Chromosome undetermined scaffold_65, wh...   123   5e-26
UniRef50_A0CTT0 Cluster: Chromosome undetermined scaffold_27, wh...   123   5e-26
UniRef50_P08799 Cluster: Myosin-2 heavy chain, non muscle; n=5; ...   123   5e-26
UniRef50_Q0IVY3 Cluster: Os10g0547000 protein; n=4; Oryza sativa...   122   6e-26
UniRef50_A0DSK6 Cluster: Chromosome undetermined scaffold_61, wh...   122   6e-26
UniRef50_A4QRL5 Cluster: Putative uncharacterized protein; n=1; ...   122   6e-26
UniRef50_UPI00015B5411 Cluster: PREDICTED: similar to SD07366p; ...   122   8e-26
UniRef50_Q4S7F6 Cluster: Chromosome 13 SCAF14715, whole genome s...   122   8e-26
UniRef50_Q115P0 Cluster: Chromosome segregation ATPase-like prot...   122   8e-26
UniRef50_Q232U4 Cluster: Putative uncharacterized protein; n=1; ...   122   8e-26
UniRef50_A0D4V9 Cluster: Chromosome undetermined scaffold_38, wh...   122   8e-26
UniRef50_A0CY92 Cluster: Chromosome undetermined scaffold_31, wh...   122   8e-26
UniRef50_A0CY31 Cluster: Chromosome undetermined scaffold_30, wh...   122   8e-26
UniRef50_A0C7H6 Cluster: Chromosome undetermined scaffold_155, w...   122   8e-26
UniRef50_A5E429 Cluster: Putative uncharacterized protein; n=1; ...   122   8e-26
UniRef50_UPI00006A0892 Cluster: Hook-related protein 1; n=1; Xen...   122   1e-25
UniRef50_Q155P7 Cluster: LEK1; n=19; Glires|Rep: LEK1 - Mus musc...   122   1e-25
UniRef50_A0DQA4 Cluster: Chromosome undetermined scaffold_6, who...   122   1e-25
UniRef50_A0CHZ3 Cluster: Chromosome undetermined scaffold_186, w...   122   1e-25
UniRef50_A0CGR6 Cluster: Chromosome undetermined scaffold_18, wh...   122   1e-25
UniRef50_A0C824 Cluster: Chromosome undetermined scaffold_157, w...   122   1e-25
UniRef50_Q10RF6 Cluster: Viral A-type inclusion protein repeat c...   121   1e-25
UniRef50_A7R618 Cluster: Chromosome undetermined scaffold_1129, ...   121   1e-25
UniRef50_A2FMF0 Cluster: Putative uncharacterized protein; n=1; ...   121   1e-25
UniRef50_UPI000150A28F Cluster: hypothetical protein TTHERM_0046...   121   2e-25
UniRef50_UPI00006CD2BD Cluster: Viral A-type inclusion protein r...   121   2e-25
UniRef50_Q612W7 Cluster: Putative uncharacterized protein CBG165...   121   2e-25
UniRef50_Q4QFM2 Cluster: Kinesin K39, putative; n=14; root|Rep: ...   121   2e-25
UniRef50_A2G9D2 Cluster: Putative uncharacterized protein; n=1; ...   121   2e-25
UniRef50_A0BM71 Cluster: Chromosome undetermined scaffold_115, w...   121   2e-25
UniRef50_UPI00006CBB68 Cluster: Kinesin motor domain containing ...   120   3e-25
UniRef50_UPI00015A629B Cluster: UPI00015A629B related cluster; n...   120   3e-25
UniRef50_Q7QII2 Cluster: ENSANGP00000005723; n=1; Anopheles gamb...   120   3e-25
UniRef50_O74424 Cluster: Nucleoporin nup211; n=1; Schizosaccharo...   120   3e-25
UniRef50_UPI0000F20708 Cluster: PREDICTED: similar to Hyperion p...   120   3e-25
UniRef50_Q869R0 Cluster: Similar to Entamoeba histolytica. Myosi...   120   3e-25
UniRef50_A2EET7 Cluster: Viral A-type inclusion protein, putativ...   120   3e-25
UniRef50_A0DXA7 Cluster: Chromosome undetermined scaffold_68, wh...   120   3e-25
UniRef50_Q14789 Cluster: Golgin subfamily B member 1; n=25; Euth...   120   3e-25
UniRef50_UPI0001556340 Cluster: PREDICTED: similar to golgi auto...   120   4e-25
UniRef50_UPI0000E80429 Cluster: PREDICTED: similar to CENPE vari...   120   4e-25
UniRef50_UPI00006CBA9F Cluster: Viral A-type inclusion protein r...   120   4e-25
UniRef50_Q22HK2 Cluster: Viral A-type inclusion protein repeat c...   120   4e-25
UniRef50_A0CQ96 Cluster: Chromosome undetermined scaffold_24, wh...   120   4e-25
UniRef50_A0BI23 Cluster: Chromosome undetermined scaffold_109, w...   120   4e-25
UniRef50_Q02455 Cluster: Protein MLP1; n=2; Saccharomyces cerevi...   120   4e-25
UniRef50_UPI000155D3DD Cluster: PREDICTED: similar to centromere...   119   6e-25
UniRef50_Q63ZU6 Cluster: LOC494731 protein; n=6; Tetrapoda|Rep: ...   119   6e-25
UniRef50_Q585H6 Cluster: Putative uncharacterized protein; n=2; ...   119   6e-25
UniRef50_Q5A0Z6 Cluster: Putative uncharacterized protein; n=3; ...   119   6e-25
UniRef50_P54697 Cluster: Myosin IJ heavy chain; n=3; Dictyosteli...   119   6e-25
UniRef50_UPI00004D936A Cluster: Centrosomal protein 2 (Centrosom...   119   8e-25
UniRef50_Q6BFF0 Cluster: Guanylate nucleotide binding protein, p...   119   8e-25
UniRef50_A5KBH9 Cluster: Putative uncharacterized protein; n=1; ...   119   8e-25
UniRef50_A2FMV8 Cluster: Surface antigen repeat-containing prote...   119   8e-25
UniRef50_A2F8Y3 Cluster: Putative uncharacterized protein; n=8; ...   119   8e-25
UniRef50_A0D367 Cluster: Chromosome undetermined scaffold_36, wh...   119   8e-25
UniRef50_A0CU18 Cluster: Chromosome undetermined scaffold_28, wh...   119   8e-25
UniRef50_Q4PGJ7 Cluster: Putative uncharacterized protein; n=1; ...   119   8e-25
UniRef50_UPI00006CC842 Cluster: hypothetical protein TTHERM_0028...   118   1e-24
UniRef50_Q25662 Cluster: Repeat organellar protein; n=5; Plasmod...   118   1e-24
UniRef50_A2FNC4 Cluster: Variable membrane protein, putative; n=...   118   1e-24
UniRef50_P30622 Cluster: CAP-Gly domain-containing linker protei...   118   1e-24
UniRef50_UPI0000D563E7 Cluster: PREDICTED: similar to Centromeri...   118   1e-24
UniRef50_UPI00006CB656 Cluster: hypothetical protein TTHERM_0044...   118   1e-24
UniRef50_Q233E2 Cluster: Putative uncharacterized protein; n=1; ...   118   1e-24
UniRef50_Q22RB8 Cluster: Putative uncharacterized protein; n=1; ...   118   1e-24
UniRef50_Q22257 Cluster: Putative uncharacterized protein hcp-2;...   118   1e-24
UniRef50_A0DAF8 Cluster: Chromosome undetermined scaffold_43, wh...   118   1e-24
UniRef50_UPI0000F204C0 Cluster: PREDICTED: similar to Viral A-ty...   118   2e-24
UniRef50_UPI0000DB748D Cluster: PREDICTED: similar to Megator CG...   118   2e-24
UniRef50_O97291 Cluster: Putative uncharacterized protein MAL3P7...   118   2e-24
UniRef50_A7TIT7 Cluster: Putative uncharacterized protein; n=1; ...   118   2e-24
UniRef50_UPI00006CD8BD Cluster: hypothetical protein TTHERM_0052...   117   2e-24
UniRef50_Q4T443 Cluster: Chromosome undetermined SCAF9830, whole...   117   2e-24
UniRef50_Q949K0 Cluster: Putative centromere protein; n=1; Solan...   117   2e-24
UniRef50_A2FTZ2 Cluster: Repeated sequence found in lipoprotein ...   117   2e-24
UniRef50_A2F6M0 Cluster: Putative uncharacterized protein; n=1; ...   117   2e-24
UniRef50_A0D7Y1 Cluster: Chromosome undetermined scaffold_40, wh...   117   2e-24
UniRef50_A7TNK0 Cluster: Putative uncharacterized protein; n=1; ...   117   2e-24
UniRef50_P35749 Cluster: Myosin-11; n=123; Eukaryota|Rep: Myosin...   117   2e-24
UniRef50_UPI0000E48EEB Cluster: PREDICTED: similar to Viral A-ty...   117   3e-24
UniRef50_UPI00004999D2 Cluster: conserved hypothetical protein; ...   117   3e-24
UniRef50_A0E680 Cluster: Chromosome undetermined scaffold_8, who...   117   3e-24
UniRef50_Q15643 Cluster: Thyroid receptor-interacting protein 11...   117   3e-24
UniRef50_UPI0000E46F7D Cluster: PREDICTED: similar to Viral A-ty...   116   4e-24
UniRef50_A7QNA8 Cluster: Chromosome chr2 scaffold_132, whole gen...   116   4e-24
UniRef50_Q7QTJ5 Cluster: GLP_375_25300_33276; n=1; Giardia lambl...   116   4e-24
UniRef50_Q4YBL9 Cluster: Putative uncharacterized protein; n=5; ...   116   4e-24
UniRef50_Q22F30 Cluster: Putative uncharacterized protein; n=1; ...   116   4e-24
UniRef50_A4HCH0 Cluster: Putative uncharacterized protein; n=1; ...   116   4e-24
UniRef50_A0CKR1 Cluster: Chromosome undetermined scaffold_2, who...   116   4e-24
UniRef50_UPI0000DB7211 Cluster: PREDICTED: similar to Stretchin-...   116   5e-24
UniRef50_UPI0000D56108 Cluster: PREDICTED: similar to CG18304-PA...   116   5e-24
UniRef50_Q8IIF6 Cluster: Putative uncharacterized protein; n=3; ...   116   5e-24
UniRef50_A2F0Q2 Cluster: Putative uncharacterized protein; n=1; ...   116   5e-24
UniRef50_UPI00006CFF95 Cluster: hypothetical protein TTHERM_0072...   116   7e-24
UniRef50_Q0DUY3 Cluster: Os03g0161100 protein; n=1; Oryza sativa...   116   7e-24
UniRef50_Q6A178 Cluster: Myosin tail 1 protein; n=4; Cryptospori...   116   7e-24
UniRef50_A0BXA6 Cluster: Chromosome undetermined scaffold_134, w...   115   9e-24
UniRef50_A2FHD4 Cluster: Trichohyalin, putative; n=1; Trichomona...   115   1e-23
UniRef50_A0DEE6 Cluster: Chromosome undetermined scaffold_48, wh...   115   1e-23
UniRef50_A0CX58 Cluster: Chromosome undetermined scaffold_3, who...   115   1e-23
UniRef50_Q8I659 Cluster: Putative uncharacterized protein PFB076...   114   2e-23
UniRef50_Q8I525 Cluster: Putative uncharacterized protein; n=1; ...   114   2e-23
UniRef50_Q1RLC7 Cluster: Zinc finger protein; n=1; Ciona intesti...   114   2e-23
UniRef50_O76447 Cluster: Holocentric chromosome binding protein ...   114   2e-23
UniRef50_A0CS47 Cluster: Chromosome undetermined scaffold_26, wh...   114   2e-23
UniRef50_A0C6A2 Cluster: Chromosome undetermined scaffold_151, w...   114   2e-23
UniRef50_Q2SR09 Cluster: Membrane protein, putative; n=1; Mycopl...   113   3e-23
UniRef50_Q7XEH4 Cluster: Expressed protein; n=5; Oryza sativa|Re...   113   3e-23
UniRef50_Q7RC59 Cluster: Putative uncharacterized protein PY0592...   113   3e-23
UniRef50_Q21022 Cluster: Putative uncharacterized protein; n=2; ...   113   3e-23
UniRef50_Q16XH2 Cluster: RHC18, putative; n=1; Aedes aegypti|Rep...   113   3e-23
UniRef50_A0EB09 Cluster: Chromosome undetermined scaffold_87, wh...   113   3e-23
UniRef50_A0DCN4 Cluster: Chromosome undetermined scaffold_45, wh...   113   3e-23
UniRef50_Q9BZF9 Cluster: Uveal autoantigen with coiled-coil doma...   113   3e-23
UniRef50_UPI0000E471AC Cluster: PREDICTED: similar to Hook-relat...   113   4e-23
UniRef50_UPI00006CBC08 Cluster: hypothetical protein TTHERM_0093...   113   4e-23
UniRef50_Q6E502 Cluster: Ninein-like protein; n=3; Euteleostomi|...   113   4e-23
UniRef50_Q4SEM9 Cluster: Chromosome undetermined SCAF14615, whol...   113   4e-23
UniRef50_Q2SR11 Cluster: Membrane protein, putative; n=3; Mycopl...   113   4e-23
UniRef50_A7HKY7 Cluster: S-layer domain protein; n=2; cellular o...   113   4e-23
UniRef50_A2DER5 Cluster: Putative uncharacterized protein; n=2; ...   113   4e-23
UniRef50_Q90339 Cluster: Myosin heavy chain, fast skeletal muscl...   113   4e-23
UniRef50_UPI00015B58F5 Cluster: PREDICTED: similar to kinesin-re...   112   7e-23
UniRef50_A0DSF3 Cluster: Chromosome undetermined scaffold_61, wh...   112   7e-23
UniRef50_UPI0000DB6E46 Cluster: PREDICTED: similar to restin iso...   112   9e-23
UniRef50_UPI0000D55B3E Cluster: PREDICTED: similar to CG33206-PA...   112   9e-23
UniRef50_UPI00006CA722 Cluster: hypothetical protein TTHERM_0084...   112   9e-23
UniRef50_Q57UV7 Cluster: Kinesin, putative; n=1; Trypanosoma bru...   112   9e-23
UniRef50_Q4CT56 Cluster: Putative uncharacterized protein; n=2; ...   112   9e-23
UniRef50_A0E285 Cluster: Chromosome undetermined scaffold_74, wh...   112   9e-23
UniRef50_Q7PVQ7 Cluster: ENSANGP00000023159; n=1; Anopheles gamb...   111   1e-22
UniRef50_Q6LF09 Cluster: Putative uncharacterized protein; n=6; ...   111   1e-22
UniRef50_A2ETQ3 Cluster: Viral A-type inclusion protein, putativ...   111   1e-22
UniRef50_A5DJG0 Cluster: Putative uncharacterized protein; n=1; ...   111   1e-22
UniRef50_UPI00006CB786 Cluster: hypothetical protein TTHERM_0034...   111   2e-22
UniRef50_Q9XIP6 Cluster: F13O11.30 protein; n=3; Arabidopsis tha...   111   2e-22
UniRef50_Q00ZD8 Cluster: Myosin class II heavy chain; n=2; Virid...   111   2e-22
UniRef50_P92021 Cluster: Putative uncharacterized protein eea-1;...   111   2e-22
UniRef50_A0BQG1 Cluster: Chromosome undetermined scaffold_120, w...   111   2e-22
UniRef50_Q6BNV2 Cluster: Debaryomyces hansenii chromosome E of s...   111   2e-22
UniRef50_UPI000155602C Cluster: PREDICTED: similar to pericentri...   111   2e-22
UniRef50_UPI00015A769C Cluster: UPI00015A769C related cluster; n...   111   2e-22
UniRef50_UPI0000ECD074 Cluster: Golgin subfamily B member 1 (Gia...   111   2e-22
UniRef50_Q4RLC8 Cluster: Chromosome 21 SCAF15022, whole genome s...   111   2e-22
UniRef50_A2FRC3 Cluster: Putative uncharacterized protein; n=1; ...   111   2e-22
UniRef50_UPI00004D7618 Cluster: Hook-related protein 1; n=1; Xen...   110   3e-22
UniRef50_Q8RCY8 Cluster: ATPase involved in DNA repair; n=3; The...   110   3e-22
UniRef50_Q4DQS9 Cluster: Putative uncharacterized protein; n=2; ...   110   3e-22
UniRef50_Q4D1D3 Cluster: Myosin heavy chain, putative; n=4; Tryp...   110   3e-22
UniRef50_A2E4S4 Cluster: Viral A-type inclusion protein, putativ...   110   3e-22
UniRef50_A2DXJ2 Cluster: Viral A-type inclusion protein, putativ...   110   3e-22
UniRef50_A0D5W3 Cluster: Chromosome undetermined scaffold_39, wh...   110   3e-22
UniRef50_Q59UF5 Cluster: Potential GRIP domain Golgi protein; n=...   110   3e-22
UniRef50_P32380 Cluster: Protein NUF1; n=2; Saccharomyces cerevi...   110   3e-22
UniRef50_UPI0001509CEA Cluster: hypothetical protein TTHERM_0031...   110   4e-22
UniRef50_A2G463 Cluster: Putative uncharacterized protein; n=1; ...   110   4e-22
UniRef50_A0E891 Cluster: Chromosome undetermined scaffold_82, wh...   110   4e-22
UniRef50_Q6FTH3 Cluster: Similar to sp|Q02455 Saccharomyces cere...   110   4e-22
UniRef50_Q23ZG7 Cluster: Peptidase family M1 containing protein;...   109   5e-22
UniRef50_A0CQS2 Cluster: Chromosome undetermined scaffold_24, wh...   109   5e-22
UniRef50_A0BBG4 Cluster: Chromosome undetermined scaffold_1, who...   109   5e-22
UniRef50_Q6VGS5 Cluster: Protein Daple; n=23; Amniota|Rep: Prote...   109   5e-22
UniRef50_UPI00006CEB8C Cluster: Viral A-type inclusion protein r...   109   6e-22
UniRef50_Q9VXU2 Cluster: CG33206-PA, isoform A; n=2; Drosophila ...   109   6e-22
UniRef50_Q22GJ1 Cluster: Putative uncharacterized protein; n=1; ...   109   6e-22
UniRef50_Q7S6K9 Cluster: Putative uncharacterized protein NCU048...   109   6e-22
UniRef50_UPI0000D5750B Cluster: PREDICTED: similar to CG8274-PA;...   109   8e-22
UniRef50_Q8T8Q5 Cluster: SD05887p; n=3; Sophophora|Rep: SD05887p...   109   8e-22
UniRef50_A0EI89 Cluster: Chromosome undetermined scaffold_98, wh...   109   8e-22
UniRef50_UPI000065E69E Cluster: Homolog of Brachydanio rerio "Ve...   108   1e-21
UniRef50_Q381P0 Cluster: Putative uncharacterized protein; n=1; ...   108   1e-21
UniRef50_Q22SU9 Cluster: Putative uncharacterized protein; n=1; ...   108   1e-21
UniRef50_A4HW55 Cluster: Kinesin K39, putative; n=2; Leishmania|...   108   1e-21
UniRef50_A2F5K7 Cluster: Putative uncharacterized protein; n=1; ...   108   1e-21
UniRef50_A2DDW4 Cluster: Putative uncharacterized protein; n=1; ...   108   1e-21
UniRef50_A0DRJ3 Cluster: Chromosome undetermined scaffold_60, wh...   108   1e-21
UniRef50_A0CJH0 Cluster: Chromosome undetermined scaffold_2, who...   108   1e-21
UniRef50_UPI00006D00EC Cluster: hypothetical protein TTHERM_0082...   108   1e-21
UniRef50_UPI00006CB5F6 Cluster: hypothetical protein TTHERM_0053...   108   1e-21
UniRef50_Q22X39 Cluster: Putative uncharacterized protein; n=1; ...   108   1e-21
UniRef50_A2EC28 Cluster: Viral A-type inclusion protein, putativ...   108   1e-21
UniRef50_A0DLY5 Cluster: Chromosome undetermined scaffold_56, wh...   108   1e-21
UniRef50_A0C8T7 Cluster: Chromosome undetermined scaffold_159, w...   108   1e-21
UniRef50_A0BL16 Cluster: Chromosome undetermined scaffold_113, w...   108   1e-21
UniRef50_UPI00006CC0B5 Cluster: hypothetical protein TTHERM_0021...   107   2e-21
UniRef50_Q4RJ17 Cluster: Chromosome 1 SCAF15039, whole genome sh...   107   2e-21
UniRef50_A2DQ51 Cluster: Putative uncharacterized protein; n=1; ...   107   2e-21
UniRef50_A0EAD2 Cluster: Chromosome undetermined scaffold_86, wh...   107   2e-21
UniRef50_A0CHD4 Cluster: Chromosome undetermined scaffold_180, w...   107   2e-21
UniRef50_UPI000150A032 Cluster: hypothetical protein TTHERM_0034...   107   2e-21
UniRef50_UPI0000D56AC0 Cluster: PREDICTED: similar to CG30337-PB...   107   2e-21
UniRef50_UPI00006CBDCB Cluster: hypothetical protein TTHERM_0031...   107   2e-21
UniRef50_Q4SSK2 Cluster: Chromosome 15 SCAF14367, whole genome s...   107   2e-21
UniRef50_Q5CHP8 Cluster: T10G3.5; n=2; Cryptosporidium|Rep: T10G...   107   2e-21
UniRef50_Q54DR3 Cluster: Calponin homology (CH) domain-containin...   107   2e-21
UniRef50_A2DES2 Cluster: Putative uncharacterized protein; n=1; ...   107   2e-21
UniRef50_Q2SSN4 Cluster: Lipoprotein, putative; n=3; Mycoplasma|...   107   3e-21
UniRef50_A6C0X8 Cluster: Putative uncharacterized protein; n=1; ...   107   3e-21
UniRef50_Q8I5X5 Cluster: Putative uncharacterized protein; n=1; ...   107   3e-21
UniRef50_Q22AV6 Cluster: Putative uncharacterized protein; n=1; ...   107   3e-21
UniRef50_O00905 Cluster: Putative uncharacterized protein; n=1; ...   107   3e-21
UniRef50_A0DAV2 Cluster: Chromosome undetermined scaffold_43, wh...   107   3e-21
UniRef50_A0CTR2 Cluster: Chromosome undetermined scaffold_27, wh...   107   3e-21
UniRef50_A5E4B9 Cluster: Putative uncharacterized protein; n=1; ...   107   3e-21
UniRef50_Q7RI76 Cluster: Putative uncharacterized protein PY0375...   106   4e-21
UniRef50_UPI0000E4801E Cluster: PREDICTED: similar to sarcoma an...   106   6e-21
UniRef50_UPI00004D1979 Cluster: centromere protein F (350/400kD)...   106   6e-21
UniRef50_Q54L07 Cluster: Zipper-like domain-containing protein; ...   106   6e-21
UniRef50_Q22WE5 Cluster: Leucine Rich Repeat family protein; n=1...   106   6e-21
UniRef50_A0BNU4 Cluster: Chromosome undetermined scaffold_119, w...   106   6e-21
UniRef50_P70012 Cluster: Nuclear/mitotic apparatus protein; n=3;...   105   8e-21
UniRef50_Q22MK1 Cluster: Putative uncharacterized protein; n=1; ...   105   8e-21
UniRef50_A2G5Q5 Cluster: Putative uncharacterized protein; n=1; ...   105   8e-21
UniRef50_A2FAD3 Cluster: Putative uncharacterized protein; n=1; ...   105   8e-21
UniRef50_A2E4A2 Cluster: Putative uncharacterized protein; n=1; ...   105   8e-21
UniRef50_A0DU61 Cluster: Chromosome undetermined scaffold_64, wh...   105   8e-21
UniRef50_A0D1B6 Cluster: Chromosome undetermined scaffold_34, wh...   105   8e-21
UniRef50_A2FMP7 Cluster: Putative uncharacterized protein; n=1; ...   105   1e-20
UniRef50_A2F798 Cluster: Putative uncharacterized protein; n=1; ...   105   1e-20
UniRef50_A2ESG7 Cluster: Viral A-type inclusion protein, putativ...   105   1e-20
UniRef50_A7TM73 Cluster: Putative uncharacterized protein; n=1; ...   105   1e-20
UniRef50_P12270 Cluster: Nucleoprotein TPR; n=57; Euteleostomi|R...   105   1e-20
UniRef50_Q11102 Cluster: Putative protein tag-278; n=2; Caenorha...   105   1e-20
UniRef50_P10567 Cluster: Paramyosin; n=23; Bilateria|Rep: Paramy...   105   1e-20
UniRef50_UPI0000E468ED Cluster: PREDICTED: similar to Restin (Re...   105   1e-20
UniRef50_Q702H4 Cluster: FYVE and coiled-coil; n=2; Gallus gallu...   105   1e-20
UniRef50_Q17E94 Cluster: Putative uncharacterized protein; n=2; ...   105   1e-20
UniRef50_A0BRK7 Cluster: Chromosome undetermined scaffold_123, w...   105   1e-20
UniRef50_Q08SC3 Cluster: Adventurous gliding protein Z; n=1; Sti...   104   2e-20
UniRef50_Q9NCG0 Cluster: Kinesin-like kinetochore motor protein ...   104   2e-20
UniRef50_Q22RA5 Cluster: Putative uncharacterized protein; n=1; ...   104   2e-20
UniRef50_A7SQE6 Cluster: Predicted protein; n=1; Nematostella ve...   104   2e-20
UniRef50_A1Z8P9 Cluster: CG8274-PA; n=4; Drosophila melanogaster...   104   2e-20
UniRef50_Q6BI71 Cluster: Similar to CA4409|IPF13151 Candida albi...   104   2e-20
UniRef50_UPI00006CFADD Cluster: hypothetical protein TTHERM_0047...   104   2e-20
UniRef50_O23037 Cluster: YUP8H12.6 protein; n=3; Arabidopsis tha...   104   2e-20
UniRef50_Q382P4 Cluster: Putative uncharacterized protein; n=1; ...   104   2e-20
UniRef50_A0CXR3 Cluster: Chromosome undetermined scaffold_30, wh...   104   2e-20
UniRef50_A0BCU6 Cluster: Chromosome undetermined scaffold_10, wh...   104   2e-20
UniRef50_Q6BY65 Cluster: Debaryomyces hansenii chromosome A of s...   104   2e-20
UniRef50_UPI0000E49858 Cluster: PREDICTED: hypothetical protein;...   103   3e-20
UniRef50_UPI0000DB6FEB Cluster: PREDICTED: similar to CENP-F kin...   103   3e-20
UniRef50_UPI000023F55C Cluster: hypothetical protein FG05337.1; ...   103   3e-20
UniRef50_UPI00005679AE Cluster: UPI00005679AE related cluster; n...   103   3e-20
UniRef50_Q4RZS5 Cluster: Chromosome 18 SCAF14786, whole genome s...   103   3e-20
UniRef50_Q6FPV2 Cluster: Similar to sp|P08964 Saccharomyces cere...   103   3e-20
UniRef50_Q5AMW9 Cluster: Putative uncharacterized protein; n=2; ...   103   3e-20
UniRef50_Q0U4W1 Cluster: Putative uncharacterized protein; n=1; ...   103   3e-20
UniRef50_A0PJP3 Cluster: Putative uncharacterized protein; n=2; ...   103   4e-20
UniRef50_Q4Y6I2 Cluster: Putative uncharacterized protein; n=4; ...   103   4e-20
UniRef50_A2FU10 Cluster: Putative uncharacterized protein; n=1; ...   103   4e-20
UniRef50_A0CFU5 Cluster: Chromosome undetermined scaffold_177, w...   103   4e-20
UniRef50_A0BJN6 Cluster: Chromosome undetermined scaffold_110, w...   103   4e-20
UniRef50_O15078 Cluster: Centrosomal protein Cep290; n=48; Eumet...   103   4e-20
UniRef50_Q00VG0 Cluster: Homology to unknown gene; n=1; Ostreoco...   103   5e-20
UniRef50_Q22869 Cluster: Non-muscle myosin heavy chain II; n=3; ...   103   5e-20
UniRef50_A2DZF5 Cluster: Putative uncharacterized protein; n=1; ...   103   5e-20
UniRef50_A0CUE5 Cluster: Chromosome undetermined scaffold_28, wh...   103   5e-20
UniRef50_UPI00006CD295 Cluster: Protein kinase domain containing...   102   7e-20
UniRef50_A7PHV3 Cluster: Chromosome chr13 scaffold_17, whole gen...   102   7e-20
UniRef50_A0BP42 Cluster: Chromosome undetermined scaffold_12, wh...   102   7e-20
UniRef50_P62134 Cluster: DNA double-strand break repair rad50 AT...   102   7e-20
UniRef50_P40457 Cluster: Protein MLP2; n=2; Saccharomyces cerevi...   102   7e-20

>UniRef50_UPI0000D55C9F Cluster: PREDICTED: similar to Golgin
            subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin)
            (Golgin-245) (Protein 72.1); n=1; Tribolium
            castaneum|Rep: PREDICTED: similar to Golgin subfamily A
            member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245)
            (Protein 72.1) - Tribolium castaneum
          Length = 2217

 Score =  251 bits (615), Expect = 1e-64
 Identities = 244/1047 (23%), Positives = 473/1047 (45%), Gaps = 61/1047 (5%)

Query: 470  TNTEDVNEIAKVQEQLKQELNDEIKDV--NVKDLIEKLKSAEE--QITQLNDEIDAANKN 525
            TN     +I++  E L+ +L  E   +   +++L  KL+ ++E  ++ +L  +++ ANKN
Sbjct: 267  TNANLEKQISEKAEDLELDLKTENSRLLDKIRELEVKLEESQESEEVAKLKKQLEEANKN 326

Query: 526  MIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHL 585
            MIKVK+ HK K+K++ K I++F K+SD+N EIV+L  E   LSQK+AELEEEKG+LQL L
Sbjct: 327  MIKVKAQHKSKVKELTKKIESFKKMSDANAEIVKLEAENSRLSQKIAELEEEKGSLQLKL 386

Query: 586  VDYDSGR----MIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVE 641
            V+ DS +      E+++  K+ + E + E + K IS+LES       E+   + + D + 
Sbjct: 387  VESDSNKGSETERENELENKIQDHERMLEEKDKIISILES-------EISRSKTEIDNLN 439

Query: 642  DKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLEN 701
            +KL       + QV SE+ S+  EEQ++ + + K++L    E +  +KEQL   ++ L+ 
Sbjct: 440  EKL-------NGQVKSEMVSIQFEEQLERVESEKRQLVEENERICKEKEQLGEQLEQLKK 492

Query: 702  DKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERD 761
            +K+++  KL++YIQENM+L DKLEK+SAEK+S     I   E    Q +  ++A  +  D
Sbjct: 493  EKQEVATKLEHYIQENMELIDKLEKLSAEKVSS-AESIEIVENLTQQEKLELEAYHKNLD 551

Query: 762  LYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQED 821
            L   N+++  S+       L ES+  + +    L +K +      +E  +   +   +  
Sbjct: 552  LVGGNLKA--SEENLPQVDLNESVNELTEETSELLQKIELFTVERREVMEKMEQLKQENL 609

Query: 822  ELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQIL--LEENQNLQISLSDMQQHYNAL 879
             L  ++  + ++  V+ +   +++ E ++L  K +    LEEN  L  ++ D+ +    L
Sbjct: 610  NLNMKIKEIENNRDVLAETYEQLQSEKEQLDAKLEKFGDLEENSRLNNAIIDLNRTLADL 669

Query: 880  VEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESA 939
                    +   +  +    L +    +K    E++ L+  K  EI  L I+     ES 
Sbjct: 670  ENDNKSLQMKIEQLEESNNHLTEELEIVKNSESENRQLVESKGNEIVKL-IKEKENTESV 728

Query: 940  IRD-KKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQT 998
            I +  K + EK E+N +++T       ++K    NL   + E N  N E I   ++ +  
Sbjct: 729  IENLHKTIREK-EENFQHIT------SDFKTKYLNLQKQLNE-NSSNFEAITAPLEAKIE 780

Query: 999  QSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLE 1058
            +     +  + ++ K+ A LK+K +    L  K    Q  + + +   + K+ Q     E
Sbjct: 781  ELTAKNKDQLEKMKKIAANLKKKTQACQDLEDKFKETQARHETSLQQLDEKIEQIKILEE 840

Query: 1059 NMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKL-TFEMNIPKTEGMIISS- 1116
               E    +++  + ++   ++  +L RE    ++    TK+   EM +   E  ++ S 
Sbjct: 841  KNVELQNLITEMKVKNEVSLQQELLLTRENLGSVENSLRTKIQELEMIVETQESELVKSK 900

Query: 1117 -TIEPMSDDANNVDXXXXXXXXXXXXLKVQEE------EEFIQERSVLQEQSAKLNTELQ 1169
              +  + +  + V+            L  Q E      EE  +   +L+++   L    +
Sbjct: 901  ERVNKLEEGLSFVEERRLSLERKANELGAQLEEKEITCEEMTRSEDLLEQRLVALAAHDE 960

Query: 1170 ECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNL---LSTVAELRSSISS 1226
                K+ +    N EL G +   +E+  ++K K+E L  +   L     T+ EL      
Sbjct: 961  AIERKLQEAIVENQELLGRNRELEEEGEKMKKKIEDLGEKFRQLEREKETIEELECENEK 1020

Query: 1227 AVDQ-RGFEIAELWKQH--LAQREADFQKTEHELRVQL-SAFESKYEQLLDSVQSSTQEE 1282
               Q   FE  EL + +  L + + DF K   + ++Q    F+ + E ++   + + + +
Sbjct: 1021 LRKQVHDFE-NELKQTNDMLEESKNDFDKVNADWQLQFDEVFKERTELMIQCEKFAEELK 1079

Query: 1283 T---NKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVI---NQIEILRSEIEDEKVAFXX 1336
            T    +     ++   + KL+  E  +R  +E+   +     + E LR+ +++++V    
Sbjct: 1080 TIAEKEFGFNNELIEYKTKLEKSESEIREYEERIGQLTLEKEEFERLRNLLKEKEVELET 1139

Query: 1337 XXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVN 1396
                            +  +    + +  S+ +  +   + K  +            + N
Sbjct: 1140 KQSEIKQLIVEKDELRKLLSDKEPKPEANSLASFFDNVPEKKNEAQVETIPTFVWSGQTN 1199

Query: 1397 DAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKE 1456
            D    V + T + E  + E+ +K       L     E E+   Q  +    +  L YEK+
Sbjct: 1200 DPFDFVAQDT-KTENTNQELLEKIKTLEFMLYNTEKEKEDALHQCAQLTNELTQLVYEKQ 1258

Query: 1457 SELAILRLKMHENANHYETMQKESEIE 1483
              +    L+  +  +  +T ++  +IE
Sbjct: 1259 MPIESQILQESDIKDTPDTCKQLEKIE 1285



 Score =  214 bits (522), Expect = 2e-53
 Identities = 375/1640 (22%), Positives = 698/1640 (42%), Gaps = 169/1640 (10%)

Query: 56   RAQKCLENAALVSKRIKEHRKATAELLGRPFVPGISESLANTLKQKEILMEKIKQYKELS 115
            RA+K  +N A  +  I   +K     L R  V      LA   K ++ + E + Q K   
Sbjct: 70   RAKKSSDNGAKKTLDIPASQKIN---LLRQQVEQNKVRLAERGKSQKGIEEMVTQLKAQL 126

Query: 116  KRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNALSVLQVKMKIMETTILDL 175
              S   I +               +  +   L   +  K+  +S L  K++ +ET +LDL
Sbjct: 127  DDSQHLISQSPLNLSLQDPKIDYSENSNAQELYAVLLTKEKRISDLLAKVQKLETNVLDL 186

Query: 176  QEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDE 235
            QE + EKD +I+A+ KA T                 ++TK+QM KMQENF+A+EAE K  
Sbjct: 187  QENLKEKDSVIDARTKAITLMTENLSRKGKNTLDTLDETKEQMRKMQENFVALEAEMKAR 246

Query: 236  KQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXL 295
            + +LL+D+  K+  I+ L+E N  LE    E   E  +L  + E                
Sbjct: 247  QMKLLEDLRLKNYEIAELQETNANLEKQISE-KAEDLELDLKTENSRLLDKIRELEVKLE 305

Query: 296  AKQSIEPSCEEKTEIEE--KGSLEI-----ANMTELTKKIELLEHLN------CQIRQTN 342
              Q  E   + K ++EE  K  +++     + + ELTKKIE  + ++       ++   N
Sbjct: 306  ESQESEEVAKLKKQLEEANKNMIKVKAQHKSKVKELTKKIESFKKMSDANAEIVKLEAEN 365

Query: 343  KELENKLATMGTES-----KAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQD 397
              L  K+A +  E      K V S S KGS         N              E + ++
Sbjct: 366  SRLSQKIAELEEEKGSLQLKLVESDSNKGSETERENELENKIQ---------DHERMLEE 416

Query: 398  TDKKIN--KNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQ-L 454
             DK I+  ++EI++ +  I +LN+ L  +                    K  L+ + + +
Sbjct: 417  KDKIISILESEISRSKTEIDNLNEKLNGQVKSEMVSIQFEEQLERVESEKRQLVEENERI 476

Query: 455  EHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAE----- 509
              ++   G  L  +    ++  E+A   E   QE N E+ D   K   EK+ SAE     
Sbjct: 477  CKEKEQLGEQLEQL---KKEKQEVATKLEHYIQE-NMELIDKLEKLSAEKVSSAESIEIV 532

Query: 510  EQITQLND-EIDAANKNMIKVKSNHKLKLKQMQKT--IDNFSKVSDSNKEIVR----LTE 562
            E +TQ    E++A +KN+  V  N K   + + +    ++ +++++   E+++     T 
Sbjct: 533  ENLTQQEKLELEAYHKNLDLVGGNLKASEENLPQVDLNESVNELTEETSELLQKIELFTV 592

Query: 563  ELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQ 622
            E   + +K+ +L++E  NL + + + ++ R + ++ Y+++   +   + +L+    LE  
Sbjct: 593  ERREVMEKMEQLKQENLNLNMKIKEIENNRDVLAETYEQLQSEKEQLDAKLEKFGDLEEN 652

Query: 623  K------FDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSV-HLEEQIDALSASK 675
                    DL + L  L+     ++ K+  + +  ++ +  E++ V + E +   L  SK
Sbjct: 653  SRLNNAIIDLNRTLADLENDNKSLQMKIEQLEE-SNNHLTEELEIVKNSESENRQLVESK 711

Query: 676  -KELALVI---ENLKLDKEQLYGTIKDLENDKEDIMN-------KLQNYIQENMDLTDKL 724
              E+  +I   EN +   E L+ TI++ E + + I +        LQ  + EN    + +
Sbjct: 712  GNEIVKLIKEKENTESVIENLHKTIREKEENFQHITSDFKTKYLNLQKQLNENSSNFEAI 771

Query: 725  EKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEES 784
                  KI EL AK N ++  K++    I A ++++    +++E    K+K    R E S
Sbjct: 772  TAPLEAKIEELTAK-NKDQLEKMKK---IAANLKKKTQACQDLE---DKFKETQARHETS 824

Query: 785  IAVMEDRRYS---LERKADQLGSYLQEKQKAYSEYTIQEDELVNR--LAVLMDHDRVVEK 839
            +  ++++      LE K  +L + + E  K  +E ++Q++ L+ R  L  + +  R   +
Sbjct: 825  LQQLDEKIEQIKILEEKNVELQNLITE-MKVKNEVSLQQELLLTRENLGSVENSLRTKIQ 883

Query: 840  QL-LEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANR--TDLAESEST-K 895
            +L + +E +  EL K      E    L+  LS +++   +L  KAN     L E E T +
Sbjct: 884  ELEMIVETQESELVKSK----ERVNKLEEGLSFVEERRLSLERKANELGAQLEEKEITCE 939

Query: 896  YQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIE 955
              T+  DL          H   I +K +E     I  N ++    R+ +   EK +K IE
Sbjct: 940  EMTRSEDLLEQRLVALAAHDEAIERKLQE----AIVENQELLGRNRELEEEGEKMKKKIE 995

Query: 956  YVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLN 1015
             + +   QL+  K  IE L    E+L K   ++ D   + +QT   D  E+  N+ +K+N
Sbjct: 996  DLGEKFRQLEREKETIEELECENEKLRK---QVHDFENELKQTN--DMLEESKNDFDKVN 1050

Query: 1016 ALLK-QKDE------EIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVS 1068
            A  + Q DE      E++   +K      +       + ++L ++ TKLE  E E++   
Sbjct: 1051 ADWQLQFDEVFKERTELMIQCEKFAEELKTIAEKEFGFNNELIEYKTKLEKSESEIREYE 1110

Query: 1069 K---QLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDA 1125
            +   QL   K+  E L+ L++E++ ++ E K++++  ++ + K E   + S  EP   +A
Sbjct: 1111 ERIGQLTLEKEEFERLRNLLKEKEVEL-ETKQSEIK-QLIVEKDELRKLLSDKEP-KPEA 1167

Query: 1126 NNVDXXXXXXXXXXXXLKVQEEEEFIQERSV-----LQEQSAKLNTELQECYTKIIQLET 1180
            N++              +V+    F+             Q  K     QE   KI  LE 
Sbjct: 1168 NSLASFFDNVPEKKNEAQVETIPTFVWSGQTNDPFDFVAQDTKTENTNQELLEKIKTLEF 1227

Query: 1181 L--NTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQ-RGFEIAE 1237
            +  NTE    D ++  Q  QL ++L QL  E    + +     S I    D  +  E  E
Sbjct: 1228 MLYNTEKEKEDALH--QCAQLTNELTQLVYEKQMPIESQILQESDIKDTPDTCKQLEKIE 1285

Query: 1238 L--WKQHLAQREADFQKTEHELRVQ------------LSAFESKYEQLLDSV-QSSTQEE 1282
                K  L          E  ++V+            +S F    +     V + + Q+ 
Sbjct: 1286 FEPTKAPLVSSLEAGPVVEEPIQVKEAYLCYNDDSRNVSIFGENDDGWGCGVEEENVQKS 1345

Query: 1283 TNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXX 1342
            T      E++  L+ + ++  E +R LQ K A     IE+L  + ++ +++         
Sbjct: 1346 TEHESLNERIRVLELERENHLEEIRQLQVKSAKEKQDIELLGWQQQNRELSAKLEQFEWG 1405

Query: 1343 XXXXXXXXD---LRTENQSY-KQMQE--QSILNINEENAQLKKSSXXXXXXXXXXXXRVN 1396
                        + T N+   K++QE  ++I ++  +N +L+                  
Sbjct: 1406 DDSFTTEEKPTVVSTNNEDLAKKIQELNETIKDLTLDNEELQALLEEQRRLRIESEKTTV 1465

Query: 1397 DAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDE----FENVRQQLVEYEKRI--ED 1450
            D E  VL+   Q    + E  ++  E    L ++NDE    FE + QQ  E ++ +  +D
Sbjct: 1466 DPE--VLKHLQQQLTTNCEEKKQLQEQINELIRKNDELSEKFETIEQQKAELDELVSSKD 1523

Query: 1451 LTYEK--------ESELAILRLKMHENANHYETMQK--ESEIERVKLIEELNVKITESVS 1500
             T  K        E E+++L  ++ E  +  E ++   E++ +R KL  E+  K+    +
Sbjct: 1524 ETIVKLNETLRGIEEEVSVLTTELQEKNSQIEALKTSFEAQDDREKLANEIEEKMATLKT 1583

Query: 1501 LNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSF 1560
            +  +   L   L+E+  + N ++ ++++Q   I +L DE   L N ++ + + +++    
Sbjct: 1584 IESEKQLLFNELQEKNIQINTLRESVDSQ---IGSLKDE---LDNQIKIAQNLLEEKTLL 1637

Query: 1561 ASDTKQGRDE--QLDNTMNK 1578
            +   K+   E  +L  TM +
Sbjct: 1638 SETLKEKESEVVRLSATMEQ 1657



 Score =  175 bits (427), Expect = 6e-42
 Identities = 313/1542 (20%), Positives = 649/1542 (42%), Gaps = 146/1542 (9%)

Query: 144  VTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKI-------NEKDQIIEAKNKATTXX 196
            +  L+ T+ + +N    LQ+K++ +E +   L E++       +E  Q++E+K       
Sbjct: 659  IIDLNRTLADLENDNKSLQMKIEQLEESNNHLTEELEIVKNSESENRQLVESKGNEIVKL 718

Query: 197  XXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEA 256
                           E+  + + + +ENF  + +++K +   L K +       S+ E  
Sbjct: 719  IKEKENTESVI----ENLHKTIREKEENFQHITSDFKTKYLNLQKQLNENS---SNFEAI 771

Query: 257  NKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIE----- 311
               LEA   E++ ++    +++++              L  +  E     +T ++     
Sbjct: 772  TAPLEAKIEELTAKNKDQLEKMKKIAANLKKKTQACQDLEDKFKETQARHETSLQQLDEK 831

Query: 312  -------EKGSLEIANM-TELTKKIEL-LEHLNCQIRQTNKELENKLATMGTESKAV--- 359
                   E+ ++E+ N+ TE+  K E+ L+      R+    +EN L T   E + +   
Sbjct: 832  IEQIKILEEKNVELQNLITEMKVKNEVSLQQELLLTRENLGSVENSLRTKIQELEMIVET 891

Query: 360  -SSPSKKGSPLISR-KSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSL 417
              S   K    +++ + G +   + +    + ++E   Q  +K+I   E+ + E +++  
Sbjct: 892  QESELVKSKERVNKLEEGLSFVEERRLSLERKANELGAQLEEKEITCEEMTRSEDLLEQR 951

Query: 418  NKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHME--GPSLIHVGTNTEDV 475
               L   +  I  K            G++  + +   + ++ +E  G     +    E +
Sbjct: 952  LVALAAHDEAIERKLQEAIVENQELLGRNRELEEEGEKMKKKIEDLGEKFRQLEREKETI 1011

Query: 476  NEIAKVQEQLKQELND---EIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSN 532
             E+    E+L+++++D   E+K  N  D++E+ K+  +++   N +       + K ++ 
Sbjct: 1012 EELECENEKLRKQVHDFENELKQTN--DMLEESKNDFDKV---NADWQLQFDEVFKERTE 1066

Query: 533  HKLKLKQMQKTIDNFS-KVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSG 591
              ++ ++  + +   + K    N E++    +L     ++ E EE  G L L   +++  
Sbjct: 1067 LMIQCEKFAEELKTIAEKEFGFNNELIEYKTKLEKSESEIREYEERIGQLTLEKEEFERL 1126

Query: 592  RMI----ESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADI 647
            R +    E ++  K  E++ L   + +   LL  +  +   E + L   +D V +K    
Sbjct: 1127 RNLLKEKEVELETKQSEIKQLIVEKDELRKLLSDK--EPKPEANSLASFFDNVPEKK--- 1181

Query: 648  SQLQSDQVCSEIKSVHLEEQIDALSASKKELAL---VIENLKLDKEQLYGTIKDLENDKE 704
            ++ Q + + + + S    +  D ++   K       ++E +K  +  LY T    E +KE
Sbjct: 1182 NEAQVETIPTFVWSGQTNDPFDFVAQDTKTENTNQELLEKIKTLEFMLYNT----EKEKE 1237

Query: 705  DIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYI 764
            D +++          LT++L ++  EK   + ++I  E   K       D   Q   +  
Sbjct: 1238 DALHQCAQ-------LTNELTQLVYEKQMPIESQILQESDIKDTP----DTCKQLEKIEF 1286

Query: 765  ENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELV 824
            E  ++ L         +EE I V E   Y       +  S   E    +      E+E V
Sbjct: 1287 EPTKAPLVSSLEAGPVVEEPIQVKE--AYLCYNDDSRNVSIFGENDDGWGCGV--EEENV 1342

Query: 825  NRLAVLMDHDRVVEK-QLLEIEHENKELQKKNQILLEENQNLQ-ISLSDMQQHYNALVEK 882
             +     +H+ + E+ ++LE+E EN  L++  Q+ ++  +  Q I L   QQ    L  K
Sbjct: 1343 QKST---EHESLNERIRVLELEREN-HLEEIRQLQVKSAKEKQDIELLGWQQQNRELSAK 1398

Query: 883  ANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRD 942
              + +  +   T  + +   + +N + +  + Q L     + I+DL ++ N ++++ + +
Sbjct: 1399 LEQFEWGDDSFTT-EEKPTVVSTNNEDLAKKIQEL----NETIKDLTLD-NEELQALLEE 1452

Query: 943  KKVLNEKYEKNI---EYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKH--VQKQQ 997
            ++ L  + EK     E +  L+ QL       + L   + EL + N EL +K   +++Q+
Sbjct: 1453 QRRLRIESEKTTVDPEVLKHLQQQLTTNCEEKKQLQEQINELIRKNDELSEKFETIEQQK 1512

Query: 998  TQSPDYTEQYINEINKLNALLKQKDEEIIALNQKIN--NAQVSYMSMVSDYESKLAQFTT 1055
             +  +        I KLN  L+  +EE+  L  ++   N+Q+  +    + +    +   
Sbjct: 1513 AELDELVSSKDETIVKLNETLRGIEEEVSVLTTELQEKNSQIEALKTSFEAQDDREKLAN 1572

Query: 1056 KLENMEEEMQRVS--KQLLDSKQHNEELQI-LVREQ-DDQIKELKETKLTFEMNIPKTEG 1111
            ++E     ++ +   KQLL ++   + +QI  +RE  D QI  LK+     +  I   + 
Sbjct: 1573 EIEEKMATLKTIESEKQLLFNELQEKNIQINTLRESVDSQIGSLKDE---LDNQIKIAQN 1629

Query: 1112 MIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQEC 1171
            ++   T+  +S+     +            +  QE +  I +R     +S KL+ E +E 
Sbjct: 1630 LLEEKTL--LSETLKEKESEVVRLSATMEQM-TQEWDLRIDQRGNDVAESWKLHLESRE- 1685

Query: 1172 YTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTV-AELRSSISSA--- 1227
                       +E T  + + +++IN+L+ K   L  EN+ L   V AE+R+ +      
Sbjct: 1686 -----------SEFTQIEQLLRKEINELEEKCNALVNENNELRKNVDAEIRNEVDRVAAL 1734

Query: 1228 ---VDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETN 1284
               ++ R   I EL K  L +++ + +  + EL     + E   E ++D V     E  +
Sbjct: 1735 QQQINDRQQYINELTKT-LQEKQREVEGIQMELETTKQSLEIDKE-IVDGVLHLVVEFYD 1792

Query: 1285 KIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIED--EKVAFXXXXXXXX 1342
              VT +   SL   L+D+E  +  L+ +   +  + E +  E     E V          
Sbjct: 1793 GGVTRDH--SLIKVLKDRENVIIGLKTELESLKTRFEDIEVEKTKGLEDVQRLRVMLEER 1850

Query: 1343 XXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKV 1402
                       +E Q+ K  + +++ N+ +     ++ +            ++   + ++
Sbjct: 1851 EQTIAGLTSQVSELQNLKDYENENVQNLQQNLHDYQQINNNLSAQVQAQVAQIEAKDREL 1910

Query: 1403 LELTHQLELKDSE----IYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESE 1458
              L H +E K  E    +   T EY +T+ ++  E E ++++L E E R E+L + KES+
Sbjct: 1911 DNLRHLVEEKQRECDYAVENLTQEYRVTINEQVHEIEVLKRRLSENENRYEELLHSKESD 1970

Query: 1459 LAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAK 1518
            L  ++ ++++       + K  EIE   L  +LN KI E  SL +++ E      EE  +
Sbjct: 1971 LEGVQYELNQ-----VMVSKSKEIEG--LASQLNTKIEECESLQRKIEEQ----VEETKQ 2019

Query: 1519 TNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNK 1578
              E++  +E Q ++I  L  ++    N   +  +++    +     +     + + T  +
Sbjct: 2020 LTELRAIIEEQVLKIEELKKDLYEKSNDYDSLIAEMDISRTNVKAPEAAPPPKTEET--E 2077

Query: 1579 ELLDAVPRAELDLAMYMLHQRDVRCXXXXXXXXXXXXXRDTL 1620
            +L + V RAELDLA+YMLHQRDVRC             RDTL
Sbjct: 2078 DLTEPVSRAELDLALYMLHQRDVRCEELTVELTQLLEERDTL 2119



 Score =  107 bits (258), Expect = 2e-21
 Identities = 177/836 (21%), Positives = 371/836 (44%), Gaps = 100/836 (11%)

Query: 311  EEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLI 370
            EEK ++   N  +L KKI+ L      +   N+EL+  L     E + +   S+K +  +
Sbjct: 1412 EEKPTVVSTNNEDLAKKIQELNETIKDLTLDNEELQALL----EEQRRLRIESEKTT--V 1465

Query: 371  SRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISE 430
              +  ++   ++ +   +   + L +  ++ I KN+  +L    +++ +   + + ++S 
Sbjct: 1466 DPEVLKHLQQQLTTNCEE--KKQLQEQINELIRKND--ELSEKFETIEQQKAELDELVSS 1521

Query: 431  KDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTED-----VNEI------A 479
            KD           G +  ++ L  E Q+       +      +D      NEI       
Sbjct: 1522 KDETIVKLNETLRGIEEEVSVLTTELQEKNSQIEALKTSFEAQDDREKLANEIEEKMATL 1581

Query: 480  KVQEQLKQELNDEIKDVNVKDLIEKLK-SAEEQITQLNDEIDAANKNMIKVKSNHKLKLK 538
            K  E  KQ L +E+++ N++  I  L+ S + QI  L DE+D    N IK+  N   +  
Sbjct: 1582 KTIESEKQLLFNELQEKNIQ--INTLRESVDSQIGSLKDELD----NQIKIAQNLLEEKT 1635

Query: 539  QMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDV 598
             + +T+       +   E+VRL+  +  ++Q+     +++GN        D     +  +
Sbjct: 1636 LLSETL------KEKESEVVRLSATMEQMTQEWDLRIDQRGN--------DVAESWKLHL 1681

Query: 599  YKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYD-EVEDKLADISQLQSDQVCS 657
              +  E   + +   K I+ LE +   LV E + L++  D E+ +++  ++ LQ  Q+  
Sbjct: 1682 ESRESEFTQIEQLLRKEINELEEKCNALVNENNELRKNVDAEIRNEVDRVAALQ-QQIND 1740

Query: 658  EIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQEN 717
                   ++ I+ L+ + +E    +E ++++ E    T + LE DKE I++ + + + E 
Sbjct: 1741 R------QQYINELTKTLQEKQREVEGIQMELET---TKQSLEIDKE-IVDGVLHLVVEF 1790

Query: 718  MDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSR 777
             D                L K+  + ++ I    G+  +++      E+IE E +K    
Sbjct: 1791 YD--------GGVTRDHSLIKVLKDRENVI---IGLKTELESLKTRFEDIEVEKTKGLED 1839

Query: 778  ICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQ--EDELVNRLAVLMDHDR 835
            + RL     ++E+R  ++     Q+ S LQ   K Y    +Q  +  L +   +  +   
Sbjct: 1840 VQRLR---VMLEEREQTIAGLTSQV-SELQ-NLKDYENENVQNLQQNLHDYQQINNNLSA 1894

Query: 836  VVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALV-EKANRTD-----LA 889
             V+ Q+ +IE +++EL     ++ E+ +    ++ ++ Q Y   + E+ +  +     L+
Sbjct: 1895 QVQAQVAQIEAKDRELDNLRHLVEEKQRECDYAVENLTQEYRVTINEQVHEIEVLKRRLS 1954

Query: 890  ESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEK 949
            E+E+ +Y+  L   ES+L+ + +E   ++V K KEIE L  + NT+IE     ++ + E+
Sbjct: 1955 ENEN-RYEELLHSKESDLEGVQYELNQVMVSKSKEIEGLASQLNTKIEECESLQRKIEEQ 2013

Query: 950  YEKNIEYVTQLEAQLQEYKNNIENLNMNV-EELNKMNLELIDKHVQKQQTQSPDYTEQYI 1008
             E+  + +T+L A ++E    IE L  ++ E+ N  +  + +  + +   ++P+      
Sbjct: 2014 VEET-KQLTELRAIIEEQVLKIEELKKDLYEKSNDYDSLIAEMDISRTNVKAPE------ 2066

Query: 1009 NEINKLNALLKQKDEEIIALNQKINNAQVSY-MSMVSDYESKLAQFTTKLENMEEEMQRV 1067
                   A    K EE   L + ++ A++   + M+   + +  + T +L  + EE   +
Sbjct: 2067 -------AAPPPKTEETEDLTEPVSRAELDLALYMLHQRDVRCEELTVELTQLLEERDTL 2119

Query: 1068 SKQLLDSKQHNEELQILVREQDDQIKELK-----ETKLTFEMNIPKTEGMIISSTI 1118
              +L +  +  EEL   V  +   ++ L      E+ LT +++  KT G     TI
Sbjct: 2120 QLRLSNVLREKEELGRKVGGEGGSLEVLPKPVEVESSLTDKLSELKTVGYKKDKTI 2175



 Score =   99 bits (238), Expect = 5e-19
 Identities = 181/952 (19%), Positives = 392/952 (41%), Gaps = 65/952 (6%)

Query: 628  QELHILQQKYDEVEDKLADI-SQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLK 686
            ++ ++ Q+K DE  + L+   ++  SD    +   +   ++I+ L    ++  + +    
Sbjct: 50   EQTNVTQEKVDEYMNTLSKRRAKKSSDNGAKKTLDIPASQKINLLRQQVEQNKVRLAERG 109

Query: 687  LDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTD-KLEKMSAEKISELLAKINHEEQS 745
              ++ +   +  L+   +D  + L +    N+ L D K++        EL A +  +E+ 
Sbjct: 110  KSQKGIEEMVTQLKAQLDDSQH-LISQSPLNLSLQDPKIDYSENSNAQELYAVLLTKEK- 167

Query: 746  KIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVM-EDRRYSLERKADQLGS 804
            +I       AK+Q+ +  + +++  L +  S I    ++I +M E+     +   D L  
Sbjct: 168  RISDLL---AKVQKLETNVLDLQENLKEKDSVIDARTKAITLMTENLSRKGKNTLDTLDE 224

Query: 805  YLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQN 864
              ++ +K    +   E E+  R   L++  R+   ++ E++  N  L+K+   + E+ ++
Sbjct: 225  TKEQMRKMQENFVALEAEMKARQMKLLEDLRLKNYEIAELQETNANLEKQ---ISEKAED 281

Query: 865  LQISLSDMQQHYNALVEKANRTDLAESES------TKYQTQLRDLESNLKRITHEHQTLI 918
            L++   D++   + L++K    ++   ES       K + QL +   N+ ++  +H++ +
Sbjct: 282  LEL---DLKTENSRLLDKIRELEVKLEESQESEEVAKLKKQLEEANKNMIKVKAQHKSKV 338

Query: 919  VQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNV 978
             +  K+IE  +   +   E           K E     ++Q  A+L+E K +++ L +  
Sbjct: 339  KELTKKIESFKKMSDANAEIV---------KLEAENSRLSQKIAELEEEKGSLQ-LKLVE 388

Query: 979  EELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVS 1038
             + NK +    +  ++ +        E+    I+ L + + +   EI  LN+K+N    S
Sbjct: 389  SDSNKGSETERENELENKIQDHERMLEEKDKIISILESEISRSKTEIDNLNEKLNGQVKS 448

Query: 1039 YMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKE- 1097
             M  +  +E +L +  ++   + EE +R+ K+    +Q  E+L+ L +E+ +   +L+  
Sbjct: 449  EMVSIQ-FEEQLERVESEKRQLVEENERICKE---KEQLGEQLEQLKKEKQEVATKLEHY 504

Query: 1098 ----TKLTFEMNIPKTEGMIISSTIEPMSD--DANNVDXXXXXXXXXXXXLKVQEEEEFI 1151
                 +L  ++     E +  + +IE + +      ++              ++  EE +
Sbjct: 505  IQENMELIDKLEKLSAEKVSSAESIEIVENLTQQEKLELEAYHKNLDLVGGNLKASEENL 564

Query: 1152 QERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGH-DVVNQEQINQLKSKLEQLNTEN 1210
             +   L E   +L  E  E   KI        E+    + + QE +N L  K++++    
Sbjct: 565  PQVD-LNESVNELTEETSELLQKIELFTVERREVMEKMEQLKQENLN-LNMKIKEIENNR 622

Query: 1211 DNLLSTVAELRSSISSAVDQRGFEIAELWKQ-HLAQREADFQKTEHELRVQLSAFESKYE 1269
            D L  T  +L+S     +D +  +  +L +   L     D  +T  +L     + + K E
Sbjct: 623  DVLAETYEQLQSE-KEQLDAKLEKFGDLEENSRLNNAIIDLNRTLADLENDNKSLQMKIE 681

Query: 1270 QLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIED 1329
            QL +S    T+E   +IV   +  + Q       E ++ ++EK  +  + IE L   I +
Sbjct: 682  QLEESNNHLTEEL--EIVKNSESENRQLVESKGNEIVKLIKEK-ENTESVIENLHKTIRE 738

Query: 1330 EKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQ---EQSILNINEENAQLKKSSXXXXX 1386
            ++  F                 L   + +++ +    E  I  +  +N    +       
Sbjct: 739  KEENFQHITSDFKTKYLNLQKQLNENSSNFEAITAPLEAKIEELTAKNKDQLEKMKKIAA 798

Query: 1387 XXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFEN-VRQQLVEYE 1445
                      D E K  E   + E    ++ +K  +  I L ++N E +N + +  V+ E
Sbjct: 799  NLKKKTQACQDLEDKFKETQARHETSLQQLDEKIEQIKI-LEEKNVELQNLITEMKVKNE 857

Query: 1446 KRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQV 1505
              ++         L  +   +       E + +  E E VK  E +N K+ E +S    V
Sbjct: 858  VSLQQELLLTRENLGSVENSLRTKIQELEMIVETQESELVKSKERVN-KLEEGLSF---V 913

Query: 1506 AELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKH 1557
             E   +LE    K NE+   LE +EI      +E+T  ++++      +  H
Sbjct: 914  EERRLSLER---KANELGAQLEEKEITC----EEMTRSEDLLEQRLVALAAH 958



 Score = 94.3 bits (224), Expect = 2e-17
 Identities = 187/920 (20%), Positives = 402/920 (43%), Gaps = 114/920 (12%)

Query: 715  QENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKY 774
            QE  DL D+ E+     I++L   I   EQ+ +  +     K+ E   Y+  +    +K 
Sbjct: 23   QELSDLKDQFEQQQV-LIAQLKEMIRKNEQTNVTQE-----KVDE---YMNTLSKRRAK- 72

Query: 775  KSRICRLEESIAVMEDRRYSLERK-ADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDH 833
            KS     ++++ +   ++ +L R+  +Q    L E+ K+        +E+V +L   +D 
Sbjct: 73   KSSDNGAKKTLDIPASQKINLLRQQVEQNKVRLAERGKSQKGI----EEMVTQLKAQLDD 128

Query: 834  DRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESES 893
             +     L+     N  LQ   +I   EN N Q       + Y  L+ K  R     ++ 
Sbjct: 129  SQ----HLISQSPLNLSLQDP-KIDYSENSNAQ-------ELYAVLLTKEKRISDLLAKV 176

Query: 894  TKYQTQLRDLESNLKRITHEHQTLIVQKKKEI----EDLEIEFNTQIESAIRDKKVLNEK 949
             K +T + DL+ NLK    E  ++I  + K I    E+L  +    +++    K+ + + 
Sbjct: 177  QKLETNVLDLQENLK----EKDSVIDARTKAITLMTENLSRKGKNTLDTLDETKEQMRKM 232

Query: 950  YEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDY-TE--Q 1006
             E  +    +++A+  +   ++   N  + EL + N  L  +  +K +    D  TE  +
Sbjct: 233  QENFVALEAEMKARQMKLLEDLRLKNYEIAELQETNANLEKQISEKAEDLELDLKTENSR 292

Query: 1007 YINEINKLNALLK--QKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEM 1064
             +++I +L   L+  Q+ EE+  L +++  A  + + + + ++SK+ + T K+E+ ++ M
Sbjct: 293  LLDKIRELEVKLEESQESEEVAKLKKQLEEANKNMIKVKAQHKSKVKELTKKIESFKK-M 351

Query: 1065 QRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDD 1124
               + +++  +  N  L         +I EL+E K + ++ + +++    S T E  ++ 
Sbjct: 352  SDANAEIVKLEAENSRLS-------QKIAELEEEKGSLQLKLVESDSNKGSET-ERENEL 403

Query: 1125 ANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKII---QLETL 1181
             N +             + + E E   + ++ +   + KLN +++     I    QLE +
Sbjct: 404  ENKIQDHERMLEEKDKIISILESE-ISRSKTEIDNLNEKLNGQVKSEMVSIQFEEQLERV 462

Query: 1182 NTELTGHDVVNQ----------EQINQLKSKLEQLNTENDNLLSTVAEL-----RSSISS 1226
             +E       N+          EQ+ QLK + +++ T+ ++ +    EL     + S   
Sbjct: 463  ESEKRQLVEENERICKEKEQLGEQLEQLKKEKQEVATKLEHYIQENMELIDKLEKLSAEK 522

Query: 1227 AVDQRGFEIAE-LWKQHLAQREADFQKTEHELRVQLSAFESKYEQ--LLDSVQSSTQEET 1283
                   EI E L +Q   + EA + K    +   L A E    Q  L +SV   T+E +
Sbjct: 523  VSSAESIEIVENLTQQEKLELEA-YHKNLDLVGGNLKASEENLPQVDLNESVNELTEETS 581

Query: 1284 NKIVTMEQVTSLQNKLQDKEEHLR----NLQEKYADVINQIEILRSEIEDEKVAFXXXXX 1339
              +  +E  T  + ++ +K E L+    NL  K  ++ N  ++L    E  +        
Sbjct: 582  ELLQKIELFTVERREVMEKMEQLKQENLNLNMKIKEIENNRDVLAETYEQLQ-------- 633

Query: 1340 XXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAE 1399
                        L  + + +  ++E S   +N     L ++             ++   E
Sbjct: 634  -------SEKEQLDAKLEKFGDLEENS--RLNNAIIDLNRTLADLENDNKSLQMKIEQLE 684

Query: 1400 AKVLELTHQLEL-KDSE------IYQKTHEYTITLTQR-NDE--FENVRQQLVEYEKRIE 1449
                 LT +LE+ K+SE      +  K +E    + ++ N E   EN+ + + E E+  +
Sbjct: 685  ESNNHLTEELEIVKNSESENRQLVESKGNEIVKLIKEKENTESVIENLHKTIREKEENFQ 744

Query: 1450 DLTYEKESELAILRLKMHENANHYE--TMQKESEIERVKLIEELNVKITESVSLN-KQVA 1506
             +T + +++   L+ +++EN++++E  T   E++IE +    +  ++  + ++ N K+  
Sbjct: 745  HITSDFKTKYLNLQKQLNENSSNFEAITAPLEAKIEELTAKNKDQLEKMKKIAANLKKKT 804

Query: 1507 ELNKALEEEVAKTN-EMQTALE--NQEIE-IVTLNDEITNLQNMVRASSSKIQKHVSFAS 1562
            +  + LE++  +T    +T+L+  +++IE I  L ++   LQN++  +  K++  VS   
Sbjct: 805  QACQDLEDKFKETQARHETSLQQLDEKIEQIKILEEKNVELQNLI--TEMKVKNEVSLQQ 862

Query: 1563 DTKQGRDE--QLDNTMNKEL 1580
            +    R+    ++N++  ++
Sbjct: 863  ELLLTRENLGSVENSLRTKI 882



 Score = 66.5 bits (155), Expect = 6e-09
 Identities = 135/684 (19%), Positives = 290/684 (42%), Gaps = 52/684 (7%)

Query: 297  KQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTES 356
            +Q +  +CEEK +++E+ +  I    EL++K E +E    ++ +     +  +  +    
Sbjct: 1474 QQQLTTNCEEKKQLQEQINELIRKNDELSEKFETIEQQKAELDELVSSKDETIVKLNETL 1533

Query: 357  KAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQS 416
            + +       +  +  K+ +  A K     +Q   E L  + ++K+    +  +E   Q 
Sbjct: 1534 RGIEEEVSVLTTELQEKNSQIEALKTSFE-AQDDREKLANEIEEKMAT--LKTIESEKQL 1590

Query: 417  LNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIH--VGTNTED 474
            L  +L +K   I+               KD L  Q+++  Q  +E  +L+   +     +
Sbjct: 1591 LFNELQEKNIQINTLRESVDSQIGSL--KDELDNQIKIA-QNLLEEKTLLSETLKEKESE 1647

Query: 475  VNEIAKVQEQLKQELNDEIKDVNVKDLIEK----LKSAEEQITQ----LNDEI-DAANKN 525
            V  ++   EQ+ QE +  I D    D+ E     L+S E + TQ    L  EI +   K 
Sbjct: 1648 VVRLSATMEQMTQEWDLRI-DQRGNDVAESWKLHLESRESEFTQIEQLLRKEINELEEKC 1706

Query: 526  MIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHL 585
               V  N++L+     +  +   +V+   ++I    + ++ L++ + E + E   +Q+ L
Sbjct: 1707 NALVNENNELRKNVDAEIRNEVDRVAALQQQINDRQQYINELTKTLQEKQREVEGIQMEL 1766

Query: 586  VDYDSGRMIESD----VYKKMIEMENLAETR----LKAISLLESQKFDLVQELHILQQKY 637
                    I+ +    V   ++E  +   TR    +K +   E+    L  EL  L+ ++
Sbjct: 1767 ETTKQSLEIDKEIVDGVLHLVVEFYDGGVTRDHSLIKVLKDRENVIIGLKTELESLKTRF 1826

Query: 638  DEVE-DKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTI 696
            +++E +K   +  +Q  +V  E +    E+ I  L++   EL    +NLK  + +    +
Sbjct: 1827 EDIEVEKTKGLEDVQRLRVMLEER----EQTIAGLTSQVSEL----QNLKDYENENVQNL 1878

Query: 697  KDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQ--TQFGID 754
            +   +D + I N L   +Q  +   +  ++   + +  L+ +   E    ++  TQ    
Sbjct: 1879 QQNLHDYQQINNNLSAQVQAQVAQIEAKDR-ELDNLRHLVEEKQRECDYAVENLTQ-EYR 1936

Query: 755  AKIQERDLYIENIESELSKYKSRICRLEESI-AVMEDRRYSLE-------RKADQLGSYL 806
              I E+   IE ++  LS+ ++R   L  S  + +E  +Y L        ++ + L S L
Sbjct: 1937 VTINEQVHEIEVLKRRLSENENRYEELLHSKESDLEGVQYELNQVMVSKSKEIEGLASQL 1996

Query: 807  QEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQ 866
              K +       + +E V     L +   ++E+Q+L+IE   K+L +K+         + 
Sbjct: 1997 NTKIEECESLQRKIEEQVEETKQLTELRAIIEEQVLKIEELKKDLYEKSNDYDSLIAEMD 2056

Query: 867  ISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTL-IVQKKKEI 925
            IS ++++    A   K   T+      ++ +  L     + + +  E  T+ + Q  +E 
Sbjct: 2057 ISRTNVKAPEAAPPPKTEETEDLTEPVSRAELDLALYMLHQRDVRCEELTVELTQLLEER 2116

Query: 926  EDLEIEFNTQIESAIRDKKVLNEK 949
            + L++    ++ + +R+K+ L  K
Sbjct: 2117 DTLQL----RLSNVLREKEELGRK 2136


>UniRef50_Q171W5 Cluster: Lava lamp protein; n=2; Culicidae|Rep: Lava
            lamp protein - Aedes aegypti (Yellowfever mosquito)
          Length = 3407

 Score =  236 bits (578), Expect = 3e-60
 Identities = 304/1382 (21%), Positives = 613/1382 (44%), Gaps = 135/1382 (9%)

Query: 221  MQENFIAMEAEWKDEKQRLLKDIESKDVRIS-SLEEANKLLEAARFEISLEHSKLAQELE 279
            +++   A E++   EK  +++ +E K + +  +L+E   ++EA    +SL    L+ + +
Sbjct: 238  LEQELAAKESQRVPEKDEVVQGLERKILDLEEALKEKECVIEARTQAVSLMSENLSLKGK 297

Query: 280  QXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIR 339
                           +    ++     K E++    L++  + E   KI  LE +N  + 
Sbjct: 298  NTVDLLEDTKQEMYRMQSNFVQAESNMKAELDR---LQV-ELDERKSKISNLEEMNNILE 353

Query: 340  QTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTD 399
                +L  + A++  + + V   S K S L   K  ++   ++    ++L S+     TD
Sbjct: 354  TARYDLTVENASLKQKLEDVQDFSTKISEL--NKLNQSLQHRI----TELESQKYEFITD 407

Query: 400  KKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQH 459
             +  + +    +   Q L   + + E  +S K              +  I   + E + +
Sbjct: 408  AEAEQAKFGASDEKYQELLDRIHELEEELSRKAAPQEDLLEKIRSLEATIQAQKEEIETY 467

Query: 460  MEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQI--TQLND 517
             +  + +    N ++      V       L +++K+   K L  K    E ++  ++L  
Sbjct: 468  NQQQAELQ--ENLQEKTVELNVLNANFSVLQEKLKNAGPKPLFPKSAEEEAEVENSKLKQ 525

Query: 518  EIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEE 577
            ++D ANK+MIK     KLK+KQ+QK +D+F K S  ++E+VRLT+E+  L+Q++AE+EEE
Sbjct: 526  QLDEANKSMIK----SKLKIKQLQKQVDSFKKTSAVHEEVVRLTDEVQTLTQRLAEVEEE 581

Query: 578  KGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKY 637
            KGNLQLHLV+YD G + +S++ K++  +E   + +  AI LLE QK D+ ++L+  + + 
Sbjct: 582  KGNLQLHLVNYD-GSLPDSELEKRIKILETTCQNQTTAIQLLEEQKIDMTEDLNSTKTQL 640

Query: 638  DEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIK 697
            + + D++ +  Q Q+DQ  + I         D +S+ + E  L  E    D+++L   + 
Sbjct: 641  ERMRDQVKE-HQDQADQSGTVIS--------DHMSSIETEEQL--EKCVADRDRLVEQVH 689

Query: 698  DLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKIS-----ELLAKINHEEQSKIQT--- 749
             LE ++ ++  KL  Y+ ENM+L DK+EK+S EK+S     E++  +  +E+ +I++   
Sbjct: 690  QLEEERSELQQKLDRYVVENMELLDKIEKLSLEKVSSAESIEIVEGLTAKEKQEIESFEK 749

Query: 750  ----------QFGIDAKIQERDLYIENIESE--LSKYKSRICRLEESIAVMEDRRYSLER 797
                        G+D   ++R    E+ + +  L  +  R        +  ED      +
Sbjct: 750  ACRKQQLAEPPGGVDEVDRDRPSNDEDDDDDGPLQVHSERRDEPTTGDSEGEDPNSCQAK 809

Query: 798  KADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQI 857
            + ++  S L  K +    +T +  E++ +L  L   ++    +L ++  E++EL +K+  
Sbjct: 810  QREEQHSELMHKIEL---FTNERREVLEKLEALTVENQTHIDELDQLREEHQELVQKHVA 866

Query: 858  LLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTL 917
            L +  Q L+ SL+  +Q   +LVE+    + A++   K +++     S+ +    +    
Sbjct: 867  LEKVEQELKASLTKTEQEKASLVEE---LEAAKTLKAKLESEASSTPSSSQSTPSKAAAS 923

Query: 918  IVQK---KKEIEDLEIEFNTQIESAIRDKKV-LNEKYEKNIEYVTQL-EAQLQEYKNNI- 971
            ++ K   ++ +  ++ E     ++  + KK+ +++K   + + + ++  + L+EY  N+ 
Sbjct: 924  VIDKDSFEQALRSVDNEVTNYNKNKDKTKKLQISKKLSSDAKNLQKMANSLLEEYYRNLA 983

Query: 972  --ENLNMNVEELNK--MNLELIDK--HVQKQQTQSPDYTEQYINEINKLNAL---LKQKD 1022
              E + M +E+L      L  +D+   +   + Q  + T   I+++++++ L   L++K+
Sbjct: 984  ECEAMKMEIEQLKDKVQRLPEVDRTEEINGLKAQIMEMTHAQIDKVDQIDQLREDLERKN 1043

Query: 1023 EEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQ 1082
            EEI  L +++  A+ +  S  SD E +L +      N E    +   +LL  K+  E   
Sbjct: 1044 EEIGELKREMEAAREAEKS--SDEEPELLKVELNSRNDEIRELKKELELLGVKKAGE--- 1098

Query: 1083 ILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXL 1142
             +   Q   +   KE ++  E+   + + +     IE   +  N +              
Sbjct: 1099 -IEEAQAKLVAATKEIEILKELVAEQKQQL-----IETYQEHENEIAG------------ 1140

Query: 1143 KVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSK 1202
            K++E +++  +   + +Q   LN +L E   K      +  ++     + Q+Q ++++ K
Sbjct: 1141 KLKEIQDYENQAQKMADQVEDLNRQLVEVGEK--YSNDMKRQVEELKSLTQKQSDEIEHK 1198

Query: 1203 LEQLNTENDNLL---STVAELRSSISSAVDQRGF--EIAELWK---QHLAQREADFQKTE 1254
             E ++T N+ ++    TV +  + I    D+  +  E+ E  K   Q L ++     KT 
Sbjct: 1199 QETIDTLNNQIIELYKTVEDNANKIIEKEDEVQYLQELLESKKDEIQMLYEKLTVANKTA 1258

Query: 1255 HELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYA 1314
             +LR +L    +K   ++D  Q    E+ N  +  +    L  KL+    +L+    +  
Sbjct: 1259 EDLRAKLEEALAKPVPVVDEAQIKDLEQKNHDLDAKN-KELLEKLKKFAANLKKKNVQCQ 1317

Query: 1315 DVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEEN 1374
            ++  ++  L+ E+E+ +                   DL+ EN+   Q       ++N E 
Sbjct: 1318 ELEGKLASLQQELEELR---------KSAAAGMSVDDLKEENEQLSQKMH----HLNNEL 1364

Query: 1375 AQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEF 1434
             +L +                 + + +V      +E    E+ +K  E    L ++  E 
Sbjct: 1365 HKLLQLKYNLETEKQAAQHETLELKERV----QAMEANVKELEEKRQEVESQLAEQQKEL 1420

Query: 1435 ENVRQQLVEYEKRIEDL-TYEKESELAILRLKMHENANHY---ETMQKESEIE----RVK 1486
            E VR        +IE      KE    I RL+ HE    Y   E    +S++E    +  
Sbjct: 1421 ETVRNDDASKNVKIEKCKAIIKEKNKEIQRLQEHERKTSYLQDEIKMAQSKLEDFHNQTM 1480

Query: 1487 LIEELNVKITESVSLNKQVAELNKALEEEVA----KTNEMQTALENQEIEIVTLNDEITN 1542
            L+  L     E  +  K   E  +ALEEEV     K  +++  LE  E E   L  +I  
Sbjct: 1481 LLGRLKADKEELNAEMKIQVERCQALEEEVCQGAEKMRKLEVDLEISEEENKKLKSKIVK 1540

Query: 1543 LQ 1544
            L+
Sbjct: 1541 LE 1542



 Score =  193 bits (471), Expect = 3e-47
 Identities = 278/1360 (20%), Positives = 577/1360 (42%), Gaps = 114/1360 (8%)

Query: 234  DEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXX 293
            D+  +L +D+E K+  I  L+     +EAAR     E  K + E  +             
Sbjct: 1030 DQIDQLREDLERKNEEIGELKRE---MEAAR-----EAEKSSDEEPELLKVELNSRNDEI 1081

Query: 294  XLAKQSIEPSCEEKT-EIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATM 352
               K+ +E    +K  EIEE  +  +A   E+    EL+     Q+ +T +E EN++A  
Sbjct: 1082 RELKKELELLGVKKAGEIEEAQAKLVAATKEIEILKELVAEQKQQLIETYQEHENEIAGK 1141

Query: 353  GTESKAVSSPSKKGSPLISRKS------GRNTASKMKSPWSQLSSETLNQDTDKKINKNE 406
              E +   + ++K +  +   +      G   ++ MK    +L S T  Q  + +  +  
Sbjct: 1142 LKEIQDYENQAQKMADQVEDLNRQLVEVGEKYSNDMKRQVEELKSLTQKQSDEIEHKQET 1201

Query: 407  IAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLI 466
            I  L   I  L K + D    I EK+            K     ++Q+ +++      L 
Sbjct: 1202 IDTLNNQIIELYKTVEDNANKIIEKEDEVQYLQELLESKKD---EIQMLYEK------LT 1252

Query: 467  HVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEID--AANK 524
                  ED+   AK++E L + +   + +  +KDL +K    + +  +L +++   AAN 
Sbjct: 1253 VANKTAEDLR--AKLEEALAKPV-PVVDEAQIKDLEQKNHDLDAKNKELLEKLKKFAANL 1309

Query: 525  NMIKVKSNH-KLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQL 583
                V+    + KL  +Q+ ++   K + +   +  L EE   LSQK+  L  E     L
Sbjct: 1310 KKKNVQCQELEGKLASLQQELEELRKSAAAGMSVDDLKEENEQLSQKMHHLNNE-----L 1364

Query: 584  HLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDK 643
            H                K+++++   ET  +A    + +  +L + +  ++    E+E+K
Sbjct: 1365 H----------------KLLQLKYNLETEKQAA---QHETLELKERVQAMEANVKELEEK 1405

Query: 644  LADI-SQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKD-LEN 701
              ++ SQL   Q   E+++V  ++    +   K +  +  +N ++ + Q +      L++
Sbjct: 1406 RQEVESQLAEQQ--KELETVRNDDASKNVKIEKCKAIIKEKNKEIQRLQEHERKTSYLQD 1463

Query: 702  DKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERD 761
            + +   +KL+++  + M L  +L+    E  +E+  ++   +  + +   G + K+++ +
Sbjct: 1464 EIKMAQSKLEDFHNQTM-LLGRLKADKEELNAEMKIQVERCQALEEEVCQGAE-KMRKLE 1521

Query: 762  LYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQED 821
            + +E  E E  K KS+I +LE+ I+++E+RR SLER+   LG  L EKQ+ + ++   ED
Sbjct: 1522 VDLEISEEENKKLKSKIVKLEQGISLVEERRNSLERQKKLLGDKLDEKQQEFIQH---ED 1578

Query: 822  ELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVE 881
            EL+ RLA L  HD  VE +L E E E  EL  K + +  +   LQ  L+ ++    A  E
Sbjct: 1579 ELMQRLANLSQHDEAVEGKLKEKEEELLELGSKLRDVEYQRDQLQSKLNQLEAQIGAFEE 1638

Query: 882  KANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIR 941
             + R    E+E+     ++  L++ +KR+  E +  +++K  EI+ LE E   Q+     
Sbjct: 1639 SSKRASELENENYNLTQEVAALQAEVKRVLAESEAKVLEKDSEIDQLEYELTNQLSKIED 1698

Query: 942  DKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMN--LELIDKHVQKQQTQ 999
            ++K L E  E+  +  + L+ ++   + N+ +L     +L K    L++ ++ +     +
Sbjct: 1699 ERKQLQENLERTRDSNSDLQDEVVRLQENVNSLEQQRTDLEKETTWLKMQNESLNHDSNE 1758

Query: 1000 SPDYTEQYINEINKLNALLKQKDE-------EIIALNQKINNAQVSYMSMVSDYESKLAQ 1052
              +   Q + +  +L  L  Q D        EI AL Q+I + +     +  +       
Sbjct: 1759 LQELRMQIVQDQTELENLRAQCDTLAQNHQYEINALKQQIADMEAIRTQLSQNQTDDQVS 1818

Query: 1053 FTTKLENMEEEMQRVSKQLLDSKQHNEELQILVR--EQDDQIKELKET--KLTFEMNIPK 1108
               ++  ++E + +   ++   +Q N ++Q+     + +D    L+ T  + T  +   K
Sbjct: 1819 VQNEVTKLKERLDKKEAEVAQLQQKNLQMQMTASGGQVEDPFSSLQATPERSTAALE-EK 1877

Query: 1109 TEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTEL 1168
               +   +T +        ++             ++Q  ++ +Q    L+ Q A+ ++EL
Sbjct: 1878 IRELENDATWKDSRIQELQIEKDLADGSLEELRKQLQMLQQNVQNSEALEAQLAQKSSEL 1937

Query: 1169 QECYTKIIQLETLNTELTGHDVVNQEQINQL------KSKLEQLNTENDNL-LSTVAELR 1221
            ++   ++ Q       +   + +     +Q        S +   +T  +         ++
Sbjct: 1938 EQLSKQLFQTVPAKKPVQEVEAIPTFSTSQFFAAPSESSAVTLFDTAGEGWGWDEPVAVQ 1997

Query: 1222 SSISSAVDQRGFEIAELWK--QHLAQREADFQKTEHELRVQLSAF---ESKYEQLLDSVQ 1276
              ++++  ++  E+  L    + L  R     K   EL+ +L      +S+Y+QL D V 
Sbjct: 1998 QQVATSASEQSNELQMLRDEIEQLKARNEAAAKEVQELQGRLGTVVDRDSEYQQLKDEVD 2057

Query: 1277 SSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXX 1336
                +  +     ++V     KL+   + L   Q K + +  Q+    S +    V+   
Sbjct: 2058 ILRSQNAS---LNQEVDEKAAKLRSVAQSLLEEQVKVSQLEEQLHSNESAVVAPSVS--- 2111

Query: 1337 XXXXXXXXXXXXXXDLRTENQSY----KQMQEQSILNINEENAQLKKSSXXXXXXXXXXX 1392
                          DL    ++Y       +E+   ++ EE A +  S+           
Sbjct: 2112 SFFADSASQGPVFEDLIVPKKAYMCTPSASEEREEWSV-EEPAVV--STAATSQHAVGFM 2168

Query: 1393 XRVNDAEAKVLELTHQLELKD-SEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDL 1451
             +V+D E + L    +L+LK   E  +K  E     T      E ++Q L + ++R  +L
Sbjct: 2169 SKVDDRELENLREQSELQLKQIREQDEKLRESGQQYTTVQSTVERLQQDLSQLQQRYAEL 2228

Query: 1452 TYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKA 1511
                +S +A  + ++            E   E ++L +E+++       L  Q A L+  
Sbjct: 2229 EAHLQSTIASHQTEVEGKM----AALAEQNDEFLQLKDEIDI-------LRAQNASLSYE 2277

Query: 1512 LEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASS 1551
            L+E  AK   +  +L+ +++++  L +++ + ++ V A S
Sbjct: 2278 LDEATAKLKNLAQSLQEEQLKVCQLEEQLHSKESAVAAPS 2317



 Score =  175 bits (426), Expect = 8e-42
 Identities = 296/1499 (19%), Positives = 629/1499 (41%), Gaps = 139/1499 (9%)

Query: 168  METTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIA 227
            +E  ILDL+E + EK+ +IEA+ +A +                 EDTKQ+M +MQ NF+ 
Sbjct: 260  LERKILDLEEALKEKECVIEARTQAVSLMSENLSLKGKNTVDLLEDTKQEMYRMQSNFVQ 319

Query: 228  MEAEWKDEKQRLLKDIESKDVRISSLEEANKLL---------EAARFEISLEHSK-LAQE 277
             E+  K E  RL  +++ +  +IS+LEE N +L         E A  +  LE  +  + +
Sbjct: 320  AESNMKAELDRLQVELDERKSKISNLEEMNNILETARYDLTVENASLKQKLEDVQDFSTK 379

Query: 278  LEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQ 337
            + +              L  Q  E   + + E  + G+ +     EL  +I  LE    +
Sbjct: 380  ISELNKLNQSLQHRITELESQKYEFITDAEAEQAKFGASD-EKYQELLDRIHELEEELSR 438

Query: 338  IRQTNKELENKL----ATMGTESKAVSSPSKKGSPLISRKSGRNTA-SKMKSPWSQLSSE 392
                 ++L  K+    AT+  + + + + +++ + L      +    + + + +S L  +
Sbjct: 439  KAAPQEDLLEKIRSLEATIQAQKEEIETYNQQQAELQENLQEKTVELNVLNANFSVLQEK 498

Query: 393  TLNQDTDKKINKN-------EIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGK 445
              N        K+       E +KL+  +   NK ++  +  I +               
Sbjct: 499  LKNAGPKPLFPKSAEEEAEVENSKLKQQLDEANKSMIKSKLKIKQLQKQVDSFKKTSAVH 558

Query: 446  DTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIK--DVNVKDLIE 503
            + ++ +L  E Q   +  + +        ++ +         EL   IK  +   ++   
Sbjct: 559  EEVV-RLTDEVQTLTQRLAEVEEEKGNLQLHLVNYDGSLPDSELEKRIKILETTCQNQTT 617

Query: 504  KLKSAEEQITQLNDEIDAANKNMIKVKSN---HKLKLKQMQKTIDNFSKVSDSNKEIVRL 560
             ++  EEQ   + +++++    + +++     H+ +  Q    I +     ++ +++ + 
Sbjct: 618  AIQLLEEQKIDMTEDLNSTKTQLERMRDQVKEHQDQADQSGTVISDHMSSIETEEQLEKC 677

Query: 561  TEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLE 620
              +   L ++V +LEEE+  LQ  L  Y         V + M  ++ + +  L+ +S  E
Sbjct: 678  VADRDRLVEQVHQLEEERSELQQKLDRY---------VVENMELLDKIEKLSLEKVSSAE 728

Query: 621  SQKFDLVQELHILQQKYDEVEDKLADISQLQS-----DQVCSEIKSVHLEEQIDA---LS 672
            S   ++V+ L   +++  E  +K     QL       D+V  +  S   ++  D    + 
Sbjct: 729  S--IEIVEGLTAKEKQEIESFEKACRKQQLAEPPGGVDEVDRDRPSNDEDDDDDGPLQVH 786

Query: 673  ASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKI 732
            + +++     ++   D        K  E    ++M+K++ +  E  ++ +KLE ++ E  
Sbjct: 787  SERRDEPTTGDSEGEDPNSCQA--KQREEQHSELMHKIELFTNERREVLEKLEALTVENQ 844

Query: 733  SEL--LAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMED 790
            + +  L ++  E Q  +Q    ++   QE       +++ L+K +     L E +   + 
Sbjct: 845  THIDELDQLREEHQELVQKHVALEKVEQE-------LKASLTKTEQEKASLVEELEAAKT 897

Query: 791  RRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKE 850
             +  LE +A    S  Q      +   I +D     L       R V+ ++    ++NK+
Sbjct: 898  LKAKLESEASSTPSSSQSTPSKAAASVIDKDSFEQAL-------RSVDNEVTNY-NKNKD 949

Query: 851  LQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQT-QLRDLESNLKR 909
              KK QI    ++ L     ++Q+  N+L+E+  R +LAE E+ K +  QL+D    L  
Sbjct: 950  KTKKLQI----SKKLSSDAKNLQKMANSLLEEYYR-NLAECEAMKMEIEQLKDKVQRLPE 1004

Query: 910  I--THEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKY---EKNIEYVTQLEAQL 964
            +  T E   L  Q   E+   +I+   QI+    D +  NE+    ++ +E   + E   
Sbjct: 1005 VDRTEEINGLKAQIM-EMTHAQIDKVDQIDQLREDLERKNEEIGELKREMEAAREAEKSS 1063

Query: 965  QE----YKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQ 1020
             E     K  + + N  + EL K  LEL+      +  ++         EI  L  L+ +
Sbjct: 1064 DEEPELLKVELNSRNDEIRELKK-ELELLGVKKAGEIEEAQAKLVAATKEIEILKELVAE 1122

Query: 1021 KDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLL-DSKQHNE 1079
            + +++I   Q+  N     +  + DYE++  +   ++E++  ++  V ++   D K+  E
Sbjct: 1123 QKQQLIETYQEHENEIAGKLKEIQDYENQAQKMADQVEDLNRQLVEVGEKYSNDMKRQVE 1182

Query: 1080 ELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXX 1139
            EL+ L ++Q D+I+  +ET  T    I +     +  T+E   D+AN +           
Sbjct: 1183 ELKSLTQKQSDEIEHKQETIDTLNNQIIE-----LYKTVE---DNANKIIEKEDEVQYLQ 1234

Query: 1140 XXLKVQEEE-EFIQERSVLQEQSAK-LNTELQECYTKII------QLETLNTELTGHDVV 1191
              L+ +++E + + E+  +  ++A+ L  +L+E   K +      Q++ L  +    D  
Sbjct: 1235 ELLESKKDEIQMLYEKLTVANKTAEDLRAKLEEALAKPVPVVDEAQIKDLEQKNHDLDAK 1294

Query: 1192 NQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQ 1251
            N+E + +LK     L  +N        EL   ++S       E+ EL K   A    D  
Sbjct: 1295 NKELLEKLKKFAANLKKKNVQC----QELEGKLASLQQ----ELEELRKSAAAGMSVDDL 1346

Query: 1252 KTEHE-LRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQ 1310
            K E+E L  ++    ++  +LL   Q     ET K     +   L+ ++Q  E +++ L+
Sbjct: 1347 KEENEQLSQKMHHLNNELHKLL---QLKYNLETEKQAAQHETLELKERVQAMEANVKELE 1403

Query: 1311 EKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQE-QSILN 1369
            EK  +V +Q+   + E+E  +                    ++ +N+  +++QE +   +
Sbjct: 1404 EKRQEVESQLAEQQKELETVR----NDDASKNVKIEKCKAIIKEKNKEIQRLQEHERKTS 1459

Query: 1370 INEENAQLKKSSXXXXXXXXXXXXRVN------DAEAKV-LELTHQLELKDSEIYQKTHE 1422
              ++  ++ +S             R+       +AE K+ +E    LE +  +  +K  +
Sbjct: 1460 YLQDEIKMAQSKLEDFHNQTMLLGRLKADKEELNAEMKIQVERCQALEEEVCQGAEKMRK 1519

Query: 1423 YTITLTQRNDEFENVRQQLVEYEKRI---EDLTYEKESELAILRLKMHENANHY-----E 1474
              + L    +E + ++ ++V+ E+ I   E+     E +  +L  K+ E    +     E
Sbjct: 1520 LEVDLEISEEENKKLKSKIVKLEQGISLVEERRNSLERQKKLLGDKLDEKQQEFIQHEDE 1579

Query: 1475 TMQKESEI-ERVKLIE-ELNVKITESVSLNKQVAELNKALEEEVAKTNEMQT---ALENQ 1529
             MQ+ + + +  + +E +L  K  E + L  ++ ++    ++  +K N+++    A E  
Sbjct: 1580 LMQRLANLSQHDEAVEGKLKEKEEELLELGSKLRDVEYQRDQLQSKLNQLEAQIGAFEES 1639

Query: 1530 EIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAE 1588
                  L +E  NL   V A  +++++ ++ +      +D ++D  +  EL + + + E
Sbjct: 1640 SKRASELENENYNLTQEVAALQAEVKRVLAESEAKVLEKDSEIDQ-LEYELTNQLSKIE 1697



 Score =  130 bits (315), Expect = 2e-28
 Identities = 214/1051 (20%), Positives = 462/1051 (43%), Gaps = 87/1051 (8%)

Query: 306  EKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKK 365
            EK E E K SL     TE  +K  L+E L    +    +LE++ ++  T S + S+PSK 
Sbjct: 868  EKVEQELKASL---TKTE-QEKASLVEELEAA-KTLKAKLESEASS--TPSSSQSTPSKA 920

Query: 366  GSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKIN-KNEIAKLEMVIQSLNKDLVDK 424
             + +I + S       ++S  +++++   N+D  KK+    +++     +Q +   L+++
Sbjct: 921  AASVIDKDSFEQA---LRSVDNEVTNYNKNKDKTKKLQISKKLSSDAKNLQKMANSLLEE 977

Query: 425  EYV-ISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQE 483
             Y  ++E +               L    + E    ++   +       + V++I +++E
Sbjct: 978  YYRNLAECEAMKMEIEQLKDKVQRLPEVDRTEEINGLKAQIMEMTHAQIDKVDQIDQLRE 1037

Query: 484  QLKQELNDEIKDVN--VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQ 541
             L+++ N+EI ++   ++   E  KS++E+   L  E+++ N  + ++K   +L+L  ++
Sbjct: 1038 DLERK-NEEIGELKREMEAAREAEKSSDEEPELLKVELNSRNDEIRELKK--ELELLGVK 1094

Query: 542  KTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKK 601
            K      ++ ++  ++V  T+E+  L + VAE +++       L++  + +  E+++  K
Sbjct: 1095 KA----GEIEEAQAKLVAATKEIEILKELVAEQKQQ-------LIE--TYQEHENEIAGK 1141

Query: 602  MIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKS 661
            + E+++      K    +E     LV+             ++L  ++Q QSD++      
Sbjct: 1142 LKEIQDYENQAQKMADQVEDLNRQLVEVGEKYSNDMKRQVEELKSLTQKQSDEI------ 1195

Query: 662  VHLEEQIDALSASKKELALVIE---NLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENM 718
             H +E ID L+    EL   +E   N  ++KE     +++L   K+D +  L     E +
Sbjct: 1196 EHKQETIDTLNNQIIELYKTVEDNANKIIEKEDEVQYLQELLESKKDEIQMLY----EKL 1251

Query: 719  DLTDKLEKMSAEKISELLAK---INHEEQSKI--QTQFGIDAKIQERDLYIENIESELSK 773
             + +K  +    K+ E LAK   +  E Q K   Q    +DAK +E    ++   + L K
Sbjct: 1252 TVANKTAEDLRAKLEEALAKPVPVVDEAQIKDLEQKNHDLDAKNKELLEKLKKFAANLKK 1311

Query: 774  YKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDH 833
               +   LE  +A ++     L RK+   G  + + ++   + + +   L N L  L+  
Sbjct: 1312 KNVQCQELEGKLASLQQELEEL-RKSAAAGMSVDDLKEENEQLSQKMHHLNNELHKLLQL 1370

Query: 834  DRVVEKQLLEIEHENKELQKKNQIL------LEEN-QNLQISLSDMQQHYNALVEKANRT 886
               +E +    +HE  EL+++ Q +      LEE  Q ++  L++ Q+     +E     
Sbjct: 1371 KYNLETEKQAAQHETLELKERVQAMEANVKELEEKRQEVESQLAEQQKE----LETVRND 1426

Query: 887  DLAES-ESTKYQTQLRDLESNLKRIT-HEHQTLIVQKKKEIEDLEIE-FNTQIESAIR-- 941
            D +++ +  K +  +++    ++R+  HE +T  +Q + ++   ++E F+ Q     R  
Sbjct: 1427 DASKNVKIEKCKAIIKEKNKEIQRLQEHERKTSYLQDEIKMAQSKLEDFHNQTMLLGRLK 1486

Query: 942  -DKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQS 1000
             DK+ LN + +  +E    LE ++ +    +  L +++E   + N +L  K V+ +Q  S
Sbjct: 1487 ADKEELNAEMKIQVERCQALEEEVCQGAEKMRKLEVDLEISEEENKKLKSKIVKLEQGIS 1546

Query: 1001 PDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENM 1060
                E+  N + +   LL  K +E     Q+    +   M  +++          KL+  
Sbjct: 1547 --LVEERRNSLERQKKLLGDKLDE---KQQEFIQHEDELMQRLANLSQHDEAVEGKLKEK 1601

Query: 1061 EEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKET-KLTFEMNIPKTEGMIISSTIE 1119
            EEE+  +  +L D +   ++LQ  + + + QI   +E+ K   E+   + E   ++  + 
Sbjct: 1602 EEELLELGSKLRDVEYQRDQLQSKLNQLEAQIGAFEESSKRASEL---ENENYNLTQEVA 1658

Query: 1120 PMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLE 1179
             +  +   V               ++++ E  Q    L  Q +K+  E ++    + +  
Sbjct: 1659 ALQAEVKRV-------LAESEAKVLEKDSEIDQLEYELTNQLSKIEDERKQLQENLERTR 1711

Query: 1180 TLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELW 1239
              N++L    V  QE +N L+ +   L  E   L      L    +   + R   + +  
Sbjct: 1712 DSNSDLQDEVVRLQENVNSLEQQRTDLEKETTWLKMQNESLNHDSNELQELRMQIVQDQT 1771

Query: 1240 KQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTME-QVTSLQNK 1298
            +    + + D     H+   +++A + +   +       +Q +T+  V+++ +VT L+ +
Sbjct: 1772 ELENLRAQCDTLAQNHQY--EINALKQQIADMEAIRTQLSQNQTDDQVSVQNEVTKLKER 1829

Query: 1299 LQDKEEHLRNLQEKYADVINQIEILRSEIED 1329
            L  KE  +  LQ+K   +  Q+     ++ED
Sbjct: 1830 LDKKEAEVAQLQQKNLQM--QMTASGGQVED 1858



 Score =  128 bits (308), Expect = 2e-27
 Identities = 274/1421 (19%), Positives = 570/1421 (40%), Gaps = 102/1421 (7%)

Query: 212  EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANK-------LLEAAR 264
            E T Q   +  E +   +AE ++  Q    ++   +   S L+E  K         ++A 
Sbjct: 454  EATIQAQKEEIETYNQQQAELQENLQEKTVELNVLNANFSVLQEKLKNAGPKPLFPKSAE 513

Query: 265  FEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSL--EIANMT 322
             E  +E+SKL Q+L++              L KQ ++   +     EE   L  E+  +T
Sbjct: 514  EEAEVENSKLKQQLDEANKSMIKSKLKIKQLQKQ-VDSFKKTSAVHEEVVRLTDEVQTLT 572

Query: 323  ELTKKIELLEHLNCQIRQTN-------KELENKLATMGT--ESKAVSSPSKKGSPLISRK 373
            +   ++E  E  N Q+   N        ELE ++  + T  +++  +    +   +   +
Sbjct: 573  QRLAEVEE-EKGNLQLHLVNYDGSLPDSELEKRIKILETTCQNQTTAIQLLEEQKIDMTE 631

Query: 374  SGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDT 433
               +T ++++    Q+       D    +  + ++ +E   Q L K + D++ ++ +   
Sbjct: 632  DLNSTKTQLERMRDQVKEHQDQADQSGTVISDHMSSIETEEQ-LEKCVADRDRLVEQVHQ 690

Query: 434  XXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEI 493
                        D  + +  +E    +E  SL  V ++ E +  +  +  + KQE+    
Sbjct: 691  LEEERSELQQKLDRYVVE-NMELLDKIEKLSLEKV-SSAESIEIVEGLTAKEKQEIESFE 748

Query: 494  KDVNVKDLIEKLKSAEE--QITQLNDEIDAANKNMIKVKSNHKLK--LKQMQKTIDNFSK 549
            K    + L E     +E  +    NDE D  +   ++V S  + +      +    N  +
Sbjct: 749  KACRKQQLAEPPGGVDEVDRDRPSNDE-DDDDDGPLQVHSERRDEPTTGDSEGEDPNSCQ 807

Query: 550  VSDSNKEIVRLTEELHHLSQKVAELEEEKGNL----QLHLVDYDSGRMIESDVYKKMIEM 605
                 ++   L  ++   + +  E+ E+   L    Q H+ + D  R    ++ +K + +
Sbjct: 808  AKQREEQHSELMHKIELFTNERREVLEKLEALTVENQTHIDELDQLREEHQELVQKHVAL 867

Query: 606  ENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADI-SQLQSDQVCSEIKSVHL 664
            E + +    +++  E +K  LV+EL   +    ++E + +   S  QS    +    +  
Sbjct: 868  EKVEQELKASLTKTEQEKASLVEELEAAKTLKAKLESEASSTPSSSQSTPSKAAASVIDK 927

Query: 665  EEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKL 724
            +    AL +   E+    +N   DK +     K L +D +++     + ++E      + 
Sbjct: 928  DSFEQALRSVDNEVTNYNKNK--DKTKKLQISKKLSSDAKNLQKMANSLLEEYYRNLAEC 985

Query: 725  EKMSAEKISELLAKINH-EEQSKIQTQFGIDAKIQERD-LYIENIESELSKYKSRICRLE 782
            E M  E I +L  K+    E  + +   G+ A+I E     I+ ++ ++ + +  + R  
Sbjct: 986  EAMKME-IEQLKDKVQRLPEVDRTEEINGLKAQIMEMTHAQIDKVD-QIDQLREDLERKN 1043

Query: 783  ESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQE-DELVNRLAVL-MDHDRVVEKQ 840
            E I  ++ R     R+A++      E  K        E  EL   L +L +     +E+ 
Sbjct: 1044 EEIGELK-REMEAAREAEKSSDEEPELLKVELNSRNDEIRELKKELELLGVKKAGEIEEA 1102

Query: 841  LLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQL 900
              ++    KE++   +++ E+ Q L   +   Q+H N +  K       E+++ K   Q+
Sbjct: 1103 QAKLVAATKEIEILKELVAEQKQQL---IETYQEHENEIAGKLKEIQDYENQAQKMADQV 1159

Query: 901  RDLE-----------SNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEK 949
             DL            +++KR   E ++L  ++  EIE  +   +T     I   K + + 
Sbjct: 1160 EDLNRQLVEVGEKYSNDMKRQVEELKSLTQKQSDEIEHKQETIDTLNNQIIELYKTVEDN 1219

Query: 950  YEKNIEY---VTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQ 1006
              K IE    V  L+  L+  K+ I+ L   +   NK   +L  K  +      P   E 
Sbjct: 1220 ANKIIEKEDEVQYLQELLESKKDEIQMLYEKLTVANKTAEDLRAKLEEALAKPVPVVDEA 1279

Query: 1007 YINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQR 1066
             I ++ + N  L  K++E++   +K             + E KLA    +LE + +    
Sbjct: 1280 QIKDLEQKNHDLDAKNKELLEKLKKFAANLKKKNVQCQELEGKLASLQQELEELRKSAA- 1338

Query: 1067 VSKQLLDSKQHNEELQILVREQDDQIKELKETK--LTFEMNIPKTEGMIISSTIEPMSDD 1124
                + D K+ NE+L   +   ++++ +L + K  L  E    + E + +   ++ M  +
Sbjct: 1339 AGMSVDDLKEENEQLSQKMHHLNNELHKLLQLKYNLETEKQAAQHETLELKERVQAMEAN 1398

Query: 1125 ANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTE 1184
               ++             ++ E+++   E   ++   A  N ++++C   I +       
Sbjct: 1399 VKELEEKRQEVES-----QLAEQQK---ELETVRNDDASKNVKIEKCKAIIKEKNKEIQR 1450

Query: 1185 LTGHDVVN---QEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQ 1241
            L  H+      Q++I   +SKLE  + +   LL  +   +  +++ +  +  E  +  ++
Sbjct: 1451 LQEHERKTSYLQDEIKMAQSKLEDFHNQT-MLLGRLKADKEELNAEMKIQ-VERCQALEE 1508

Query: 1242 HLAQREADFQKTEHELRV---QLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTS--LQ 1296
             + Q     +K E +L +   +    +SK  +L   + S  +E  N +   +++    L 
Sbjct: 1509 EVCQGAEKMRKLEVDLEISEEENKKLKSKIVKLEQGI-SLVEERRNSLERQKKLLGDKLD 1567

Query: 1297 NKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTEN 1356
             K Q+  +H   L ++ A++    E +  ++++++                        N
Sbjct: 1568 EKQQEFIQHEDELMQRLANLSQHDEAVEGKLKEKEEELLELGSKLRDVEYQRDQLQSKLN 1627

Query: 1357 QSYKQMQ--EQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDS 1414
            Q   Q+   E+S    +E   +    +             + ++EAKVLE       KDS
Sbjct: 1628 QLEAQIGAFEESSKRASELENENYNLTQEVAALQAEVKRVLAESEAKVLE-------KDS 1680

Query: 1415 EIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYE 1474
            EI Q  +E T  L++  DE    R+QL E  +R  D   + + E  ++RL+ + N+   +
Sbjct: 1681 EIDQLEYELTNQLSKIEDE----RKQLQENLERTRDSNSDLQDE--VVRLQENVNSLEQQ 1734

Query: 1475 TMQKESEIERVKL-IEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEI 1533
                E E   +K+  E LN    E   L  Q+ +    LE   A   +  T  +N + EI
Sbjct: 1735 RTDLEKETTWLKMQNESLNHDSNELQELRMQIVQDQTELENLRA---QCDTLAQNHQYEI 1791

Query: 1534 VTLNDEITNLQNM-VRASSSKIQKHVSFASDTKQGRDEQLD 1573
              L  +I +++ +  + S ++    VS  ++  + + E+LD
Sbjct: 1792 NALKQQIADMEAIRTQLSQNQTDDQVSVQNEVTKLK-ERLD 1831



 Score =  112 bits (269), Expect = 9e-23
 Identities = 234/1151 (20%), Positives = 479/1151 (41%), Gaps = 120/1151 (10%)

Query: 523  NKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQ 582
            ++ +  ++   +L+LKQ+++  +   K+ +S ++   +   +  L Q +++L++    L+
Sbjct: 2173 DRELENLREQSELQLKQIREQDE---KLRESGQQYTTVQSTVERLQQDLSQLQQRYAELE 2229

Query: 583  LHLVDYDSGRMIESDVYKKMIEMENLAETRLK-AISLLESQKFDLVQELHILQQKYDEVE 641
             HL    +    E +     +  +N    +LK  I +L +Q   L  EL       DE  
Sbjct: 2230 AHLQSTIASHQTEVEGKMAALAEQNDEFLQLKDEIDILRAQNASLSYEL-------DEAT 2282

Query: 642  DKLADISQ-LQSDQ--VCSEIKSVHLEEQ------IDALSASKKELALVIENLKLDKEQL 692
             KL +++Q LQ +Q  VC   + +H +E       + +  A+      V E+L + K+  
Sbjct: 2283 AKLKNLAQSLQEEQLKVCQLEEQLHSKESAVAAPSVSSFFANSGAQEPVFEDLVVPKKAY 2342

Query: 693  YGTIKDLENDKEDIMNK--LQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQ 750
              T    E   +  + K  + + +  +      +E +  ++++ L  ++N ++  +++ Q
Sbjct: 2343 LCTPSASEEQDDWSVEKPMVMSTMAPSQRSAGLVESVDLQELANL-RELNEQQMKQLREQ 2401

Query: 751  FGIDAKIQERDLYIENIESELSKYKSRICRLE----ESIAVMEDRRYSLERKADQLGSYL 806
                ++ Q     +E ++ ELS+ + R  +LE     ++A  +    +L     Q  S  
Sbjct: 2402 ADQHSQTQAN---VEQLQQELSQLQQRYAQLEGHLNTTLASHQIELEALRNHQTQQNSQS 2458

Query: 807  QEKQKAYSEYTIQEDELVNRLAVL-MDHDRVVEKQ--LLEIEHENKELQKKNQILLEENQ 863
            QE+QK   +   + + L+ R   L  D D  ++ Q  L  ++ +N  L+++     +  +
Sbjct: 2459 QEEQKKLKD---ELNHLMQRNQALEQDRDAYLQLQDELDILKAQNASLRQEVDEKSDRIK 2515

Query: 864  NLQISLSDMQQHYNALVEK-ANRTDLAESESTKYQTQLRDLESNL--KRITHEHQTLIVQ 920
             +  +L++ +   + L E+ A R     S +  +  Q +   + +  + IT +    +  
Sbjct: 2516 RVCHTLTEQETRVSDLEEQLATREQHPPSTAAFFGGQQQPPAAAVFEEIITPKKAYEVEP 2575

Query: 921  KKKEIEDLEIEFNTQIESAIRDKK------VLNEKYEKNIEYVTQLEAQLQEYKNNIENL 974
                   +E +     E+A+ +K        L  +  +  +Y+ QLE + +     I  L
Sbjct: 2576 TPSSAIQVEDDCWGAEEAALEEKHQQTSSVALERRISEKDDYIRQLEMEKERLLQEIVEL 2635

Query: 975  NMNVEELNKMNLELIDK-HVQKQQTQSPDYTEQYINEINKLNALLKQKD---EEIIALNQ 1030
             +   +L K   E   K    ++++ S + +E  +    +LN  +K  +    E+ A  +
Sbjct: 2636 KVKSGKLLKKLKEYKTKSETLQRRSASMETSELDLAIQEELNTQIKTLEGRLSELQAERE 2695

Query: 1031 KINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDD 1090
            K +  + S +  +    +   +FT   E  + +M+    Q+   K+ N +LQ L    D+
Sbjct: 2696 KESTEKDSLLKRIDVLVAANERFTEMKERQDVQMEI---QVAKIKELNLKLQQLEDWGDE 2752

Query: 1091 QIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANN--VDXXXXXXXXXXXXLKVQEEE 1148
               E KE+K   ++     +   +++ ++ +  +  +  VD              V+  E
Sbjct: 2753 S--EQKESKPVEQVQPEAVDVAPLNARVQELEREVQDLKVDNEELQALLDEEKANVEILE 2810

Query: 1149 EFIQERS-VLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLN 1207
            + +Q++   +Q+   K++   Q+  T    LE+LN +         ++   L ++L+QL 
Sbjct: 2811 KRVQQKDREIQDLIEKIDLLSQDSQTIKTNLESLNQQ-------KSQETEDLSTRLKQLM 2863

Query: 1208 TENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHEL-----RVQLS 1262
            ++N  L   + ++R+    ++ Q   + A+L +Q + Q  A  Q  E E+     R++  
Sbjct: 2864 SKNTELTQQIEKMRTE---SLFQSSEQEAKLQEQ-VQQLSAQLQYKEAEIVHLGERIEQQ 2919

Query: 1263 AFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQD-------KEEHLRNLQEKYAD 1315
            A E + + L+  + +  QE  N    ++Q+ + + +LQ        KE       EK + 
Sbjct: 2920 AREDQTQSLVQEILAKNQEINNLKSRVQQLEAERQELQHNLTLQITKELASSRPDEKQSP 2979

Query: 1316 VINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENA 1375
             ++++E L  E++ EK                    L  E++    + E    NI  E  
Sbjct: 2980 RVSELERLNRELQAEK---HQMEQELQVLNDQVLRSLELEDRMKGTVLELDAKNIEIEAL 3036

Query: 1376 Q-----LKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQR 1430
            +     LK++S                A     +L  Q++    E  +    Y ITL QR
Sbjct: 3037 KTSLELLKQASEASGESASSSEQSTPTAGKSEEDLRKQIKKLSRERSELEANYRITLEQR 3096

Query: 1431 NDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEE 1490
            +  +     Q+VE          E+ +++A           H +  + E  +    L EE
Sbjct: 3097 DAHWS----QVVE----------ERGAQVA------ESWKQHVDMREAEFSVIEKSLREE 3136

Query: 1491 LNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEIT-NLQNMVRA 1549
            ++        L    +E   + E+  A  N M+ ALE QE+EIVTL +++        R 
Sbjct: 3137 ID-------RLQGDGSETPSSSEQSEAVQN-MKAALEAQELEIVTLKEQLAIRSAEYARL 3188

Query: 1550 SSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDLAMYMLHQRDVRCXXXXXX 1609
            ++      V  AS+             +    D VPR+EL+LA+YM++QRD+RC      
Sbjct: 3189 AAQVDPFAVKHASNMVTSEPRPQPAAQDG---DKVPRSELELALYMIYQRDMRCEELELE 3245

Query: 1610 XXXXXXXRDTL 1620
                   RD+L
Sbjct: 3246 LRNLLTERDSL 3256



 Score =  111 bits (268), Expect = 1e-22
 Identities = 262/1299 (20%), Positives = 539/1299 (41%), Gaps = 109/1299 (8%)

Query: 299  SIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKL-ATMGTESK 357
            S+      +T   EK +L    M +   K+   E    ++ +   EL++KL +T  T  +
Sbjct: 121  SVPIRARSETPGSEKINLLRQQMEQNRLKMAARESHKREMEERVIELKHKLESTQQTLER 180

Query: 358  AVSSPSKKG--SPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQ 415
            +V      G  + L   K GR   ++  S  +QL    ++ + D +     +  LE  ++
Sbjct: 181  SVEFGRSTGDLTLLTPLKMGRFEFNRSTSDLTQLVGSGVSSNFDVE----RLNYLEGRVK 236

Query: 416  SLNKDLVDKEYV-ISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHV-----G 469
             L ++L  KE   + EKD             +  + + +   +   +  SL+       G
Sbjct: 237  VLEQELAAKESQRVPEKDEVVQGLERKILDLEEALKEKECVIEARTQAVSLMSENLSLKG 296

Query: 470  TNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKL-------KSAEEQITQLNDEIDAA 522
             NT D+ E  K QE  + + N    + N+K  +++L       KS    + ++N+ ++ A
Sbjct: 297  KNTVDLLEDTK-QEMYRMQSNFVQAESNMKAELDRLQVELDERKSKISNLEEMNNILETA 355

Query: 523  NKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIV-RLTEELHHLSQKVAELEEEKGNL 581
              ++    ++ K KL+ +Q      S+++  N+ +  R+TE      + + + E E+   
Sbjct: 356  RYDLTVENASLKQKLEDVQDFSTKISELNKLNQSLQHRITELESQKYEFITDAEAEQAKF 415

Query: 582  QLHLVDY----DSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKY 637
                  Y    D    +E ++ +K    E+L E      + +++QK ++        +  
Sbjct: 416  GASDEKYQELLDRIHELEEELSRKAAPQEDLLEKIRSLEATIQAQKEEIETYNQQQAELQ 475

Query: 638  DEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIK 697
            + +++K  +++ L ++    + K  +   +   L     E    +EN KL K+QL    K
Sbjct: 476  ENLQEKTVELNVLNANFSVLQEKLKNAGPK--PLFPKSAEEEAEVENSKL-KQQLDEANK 532

Query: 698  DLENDKEDI--MNKLQNYIQENMDLTDKLEKMSAE--KISELLAKINHEEQSKIQTQF-G 752
             +   K  I  + K  +  ++   + +++ +++ E   +++ LA++  EE+  +Q     
Sbjct: 533  SMIKSKLKIKQLQKQVDSFKKTSAVHEEVVRLTDEVQTLTQRLAEVE-EEKGNLQLHLVN 591

Query: 753  IDAKIQERDLY--IENIESELSKYKSRICRLEES-IAVMED---RRYSLERKADQLGSYL 806
             D  + + +L   I+ +E+      + I  LEE  I + ED    +  LER  DQ+  + 
Sbjct: 592  YDGSLPDSELEKRIKILETTCQNQTTAIQLLEEQKIDMTEDLNSTKTQLERMRDQVKEHQ 651

Query: 807  QEKQKA---YSEY--TIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEE 861
             +  ++    S++  +I+ +E + +     D DR+VE Q+ ++E E  ELQ+K    + E
Sbjct: 652  DQADQSGTVISDHMSSIETEEQLEKCVA--DRDRLVE-QVHQLEEERSELQQKLDRYVVE 708

Query: 862  NQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEH-----QT 916
            N  L   L  +++     V  A   ++ E  + K + ++   E   ++            
Sbjct: 709  NMEL---LDKIEKLSLEKVSSAESIEIVEGLTAKEKQEIESFEKACRKQQLAEPPGGVDE 765

Query: 917  LIVQKKKEIEDLEIEFNTQIESAIRDKKVL--NEKYEKNIEYVTQLEAQLQEYKNNIENL 974
            +   +    ED + +   Q+ S  RD+     +E  + N     Q E Q  E  + IE  
Sbjct: 766  VDRDRPSNDEDDDDDGPLQVHSERRDEPTTGDSEGEDPNSCQAKQREEQHSELMHKIELF 825

Query: 975  -NMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKIN 1033
             N   E L K+    ++      +    D   +   E+ + +  L++ ++E+ A   K  
Sbjct: 826  TNERREVLEKLEALTVENQTHIDEL---DQLREEHQELVQKHVALEKVEQELKASLTKTE 882

Query: 1034 NAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIK 1093
              + S +  +   ++  A+  ++  +     Q    +   S    +  +  +R  D+++ 
Sbjct: 883  QEKASLVEELEAAKTLKAKLESEASSTPSSSQSTPSKAAASVIDKDSFEQALRSVDNEV- 941

Query: 1094 ELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQE 1153
                    +  N  KT+ + IS   + +S DA N+               + E E    E
Sbjct: 942  ------TNYNKNKDKTKKLQIS---KKLSSDAKNLQKMANSLLEEYYR-NLAECEAMKME 991

Query: 1154 RSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNL 1213
               L+++  +L  E+     +I  L+    E+T   +   +QI+QL+  LE+ N E    
Sbjct: 992  IEQLKDKVQRL-PEVDRT-EEINGLKAQIMEMTHAQIDKVDQIDQLREDLERKNEE---- 1045

Query: 1214 LSTVAELRSSISSA--VDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQL 1271
               + EL+  + +A   ++   E  EL K  L  R  + ++ + EL +       + E+ 
Sbjct: 1046 ---IGELKREMEAAREAEKSSDEEPELLKVELNSRNDEIRELKKELELLGVKKAGEIEEA 1102

Query: 1272 LDSVQSSTQE-ETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDE 1330
               + ++T+E E  K +  EQ   L    Q+ E  +    ++  D  NQ + +  ++ED 
Sbjct: 1103 QAKLVAATKEIEILKELVAEQKQQLIETYQEHENEIAGKLKEIQDYENQAQKMADQVEDL 1162

Query: 1331 KVAFXXXXXXXXXXXXXXXXDLR--TENQSYK-QMQEQSILNINEENAQLKKSSXXXXXX 1387
                                +L+  T+ QS + + ++++I  +N +  +L K+       
Sbjct: 1163 NRQLVEVGEKYSNDMKRQVEELKSLTQKQSDEIEHKQETIDTLNNQIIELYKT------- 1215

Query: 1388 XXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKR 1447
                  ++ + E +V  L   LE K  EI Q  +E    LT  N   E++R +L   E  
Sbjct: 1216 VEDNANKIIEKEDEVQYLQELLESKKDEI-QMLYE---KLTVANKTAEDLRAKL--EEAL 1269

Query: 1448 IEDLTYEKESELAILRLKMHE-NANHYETMQKESEIERVKLIEELNVKITESVSLNKQVA 1506
             + +    E+++  L  K H+ +A + E ++K       K    L  K  +   L  ++A
Sbjct: 1270 AKPVPVVDEAQIKDLEQKNHDLDAKNKELLEKLK-----KFAANLKKKNVQCQELEGKLA 1324

Query: 1507 ELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQN 1545
             L + L EE+ K+     ++++ + E   L+ ++ +L N
Sbjct: 1325 SLQQEL-EELRKSAAAGMSVDDLKEENEQLSQKMHHLNN 1362



 Score = 99.5 bits (237), Expect = 7e-19
 Identities = 167/864 (19%), Positives = 381/864 (44%), Gaps = 66/864 (7%)

Query: 474  DVNEIAKVQEQLKQELNDEIKDVNVKDLIE-KLKSAEEQITQLNDEIDAANKNMIKVKSN 532
            D+ E+A ++E  +Q++    +  +     +  ++  +++++QL         ++    ++
Sbjct: 2380 DLQELANLRELNEQQMKQLREQADQHSQTQANVEQLQQELSQLQQRYAQLEGHLNTTLAS 2439

Query: 533  HKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVD-YDSG 591
            H+++L+ ++       + S S +E  +L +EL+HL Q+   LE+++ +  L L D  D  
Sbjct: 2440 HQIELEALRN--HQTQQNSQSQEEQKKLKDELNHLMQRNQALEQDR-DAYLQLQDELDIL 2496

Query: 592  RMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQ 651
            +   + + +++ E  +  +     ++  E++  DL ++L   +Q             Q  
Sbjct: 2497 KAQNASLRQEVDEKSDRIKRVCHTLTEQETRVSDLEEQLATREQHPPSTAAFFGGQQQPP 2556

Query: 652  SDQVCSEI---KSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLE---NDKED 705
            +  V  EI   K  +  E   + +   ++     E   L+++    +   LE   ++K+D
Sbjct: 2557 AAAVFEEIITPKKAYEVEPTPSSAIQVEDDCWGAEEAALEEKHQQTSSVALERRISEKDD 2616

Query: 706  IMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIE 765
             + +L+    E   L  ++ ++   K  +LL K+  E ++K +T     A ++  +L + 
Sbjct: 2617 YIRQLE---MEKERLLQEIVELKV-KSGKLLKKLK-EYKTKSETLQRRSASMETSELDLA 2671

Query: 766  NIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVN 825
             I+ EL+   ++I  LE  ++ ++  R     + D L   +     A   +T  ++    
Sbjct: 2672 -IQEELN---TQIKTLEGRLSELQAEREKESTEKDSLLKRIDVLVAANERFTEMKERQDV 2727

Query: 826  RLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANR 885
            ++ + +   + +  +L ++E    E ++K    +E+ Q   + ++ +    NA V++  R
Sbjct: 2728 QMEIQVAKIKELNLKLQQLEDWGDESEQKESKPVEQVQPEAVDVAPL----NARVQELER 2783

Query: 886  T--DLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDK 943
               DL + ++ + Q  L + ++N++ +    Q    QK +EI+DL IE   +I+   +D 
Sbjct: 2784 EVQDL-KVDNEELQALLDEEKANVEILEKRVQ----QKDREIQDL-IE---KIDLLSQDS 2834

Query: 944  KVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQT----Q 999
            + +           T LE+  Q+     E+L+  +++L   N EL  + ++K +T    Q
Sbjct: 2835 QTIK----------TNLESLNQQKSQETEDLSTRLKQLMSKNTELTQQ-IEKMRTESLFQ 2883

Query: 1000 SPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLEN 1059
            S +   +   ++ +L+A L+ K+ EI+ L ++I   Q +          ++     ++ N
Sbjct: 2884 SSEQEAKLQEQVQQLSAQLQYKEAEIVHLGERIE--QQAREDQTQSLVQEILAKNQEINN 2941

Query: 1060 MEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIE 1119
            ++  +Q++  +  +  QHN  LQI  +E      + K++    E+     E       +E
Sbjct: 2942 LKSRVQQLEAERQEL-QHNLTLQI-TKELASSRPDEKQSPRVSELERLNRELQAEKHQME 2999

Query: 1120 PMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLE 1179
                  N+                ++ + + I+  ++  + S +L  +  E   +     
Sbjct: 3000 QELQVLNDQVLRSLELEDRMKGTVLELDAKNIEIEAL--KTSLELLKQASEASGESASSS 3057

Query: 1180 TLNTELTGHDVVNQEQINQLKSKLEQLNTEND-NLLSTVAELRSSISSAVDQRGFEIAEL 1238
              +T   G    ++E + +   KL +  +E + N   T+ +  +  S  V++RG ++AE 
Sbjct: 3058 EQSTPTAGK---SEEDLRKQIKKLSRERSELEANYRITLEQRDAHWSQVVEERGAQVAES 3114

Query: 1239 WKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQN- 1297
            WKQH+  REA+F   E  LR ++   +        S   S+ E++  +  M+     Q  
Sbjct: 3115 WKQHVDMREAEFSVIEKSLREEIDRLQGD-----GSETPSSSEQSEAVQNMKAALEAQEL 3169

Query: 1298 KLQDKEEHLRNLQEKYADVINQIE 1321
            ++   +E L     +YA +  Q++
Sbjct: 3170 EIVTLKEQLAIRSAEYARLAAQVD 3193



 Score = 78.6 bits (185), Expect = 1e-12
 Identities = 249/1393 (17%), Positives = 562/1393 (40%), Gaps = 116/1393 (8%)

Query: 212  EDTKQQMTKMQENFIAMEAEWKDEKQRLLK-DIESKDVRISSLEEANKLLEA-ARFEISL 269
            ++  Q++  + ++  A+E + K++++ LL+   + +DV     +  +KL +  A+     
Sbjct: 1578 DELMQRLANLSQHDEAVEGKLKEKEEELLELGSKLRDVEYQRDQLQSKLNQLEAQIGAFE 1637

Query: 270  EHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIE 329
            E SK A ELE                 K+ +    E + ++ EK S EI  +     + E
Sbjct: 1638 ESSKRASELENENYNLTQEVAALQAEVKRVL---AESEAKVLEKDS-EIDQL-----EYE 1688

Query: 330  LLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQL 389
            L   L+ +I    K+L+  L      +  +     +    ++    + T  + ++ W ++
Sbjct: 1689 LTNQLS-KIEDERKQLQENLERTRDSNSDLQDEVVRLQENVNSLEQQRTDLEKETTWLKM 1747

Query: 390  SSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLI 449
             +E+LN D+      NE+ +L M I    +D  + E + ++ DT               I
Sbjct: 1748 QNESLNHDS------NELQELRMQIV---QDQTELENLRAQCDTLAQNHQYEINALKQQI 1798

Query: 450  AQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAE 509
            A ++    Q  +  +   V       NE+ K++E+L +      K+  V  L +K  + +
Sbjct: 1799 ADMEAIRTQLSQNQTDDQVSVQ----NEVTKLKERLDK------KEAEVAQLQQK--NLQ 1846

Query: 510  EQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQ 569
             Q+T    +++    ++          L++  + ++N +   DS  + +++ ++L   S 
Sbjct: 1847 MQMTASGGQVEDPFSSLQATPERSTAALEEKIRELENDATWKDSRIQELQIEKDLADGS- 1905

Query: 570  KVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLES-QKFDLVQ 628
                LEE +  LQ+   +  +   +E+ + +K  E+E L++   + +   +  Q+ + + 
Sbjct: 1906 ----LEELRKQLQMLQQNVQNSEALEAQLAQKSSELEQLSKQLFQTVPAKKPVQEVEAIP 1961

Query: 629  ELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKK--ELALV---IE 683
                 Q      E     +     +    + + V +++Q+ A SAS++  EL ++   IE
Sbjct: 1962 TFSTSQFFAAPSESSAVTLFDTAGEGWGWD-EPVAVQQQV-ATSASEQSNELQMLRDEIE 2019

Query: 684  NLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSA---EKISELLAKIN 740
             LK   E     +++L+     ++++   Y Q+  D  D L   +A   +++ E  AK+ 
Sbjct: 2020 QLKARNEAAAKEVQELQGRLGTVVDRDSEY-QQLKDEVDILRSQNASLNQEVDEKAAKLR 2078

Query: 741  HEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKAD 800
               QS ++ Q  + ++++E+ L+            S          V ED    + +KA 
Sbjct: 2079 SVAQSLLEEQVKV-SQLEEQ-LHSNESAVVAPSVSSFFADSASQGPVFED--LIVPKKAY 2134

Query: 801  QLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLE 860
                   E+++   E++++E  +V+  A    H      ++ + E EN  L++++++ L+
Sbjct: 2135 MCTPSASEERE---EWSVEEPAVVS-TAATSQHAVGFMSKVDDRELEN--LREQSELQLK 2188

Query: 861  ENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQ 920
            + +     L +  Q Y  +     R    + + ++ Q +  +LE++L+     HQT +  
Sbjct: 2189 QIREQDEKLRESGQQYTTVQSTVER---LQQDLSQLQQRYAELEAHLQSTIASHQTEVEG 2245

Query: 921  KKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVT----QLEAQLQEYKNNIENLNM 976
            K   + +   EF  Q++  I   +  N      ++  T     L   LQE +  +  L  
Sbjct: 2246 KMAALAEQNDEF-LQLKDEIDILRAQNASLSYELDEATAKLKNLAQSLQEEQLKVCQLEE 2304

Query: 977  NV-EELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNA 1035
             +  + + +    +         Q P + +  + +   L      ++++    +  +   
Sbjct: 2305 QLHSKESAVAAPSVSSFFANSGAQEPVFEDLVVPKKAYLCTPSASEEQD----DWSVEKP 2360

Query: 1036 QVSYMSMVSDYESKLAQFT--TKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIK 1093
             V      S   + L +     +L N+ E  ++  KQL +    + + Q  V +   ++ 
Sbjct: 2361 MVMSTMAPSQRSAGLVESVDLQELANLRELNEQQMKQLREQADQHSQTQANVEQLQQELS 2420

Query: 1094 ELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQE 1153
            +L++     E ++  T   + S  IE    +A                 K+++E   + +
Sbjct: 2421 QLQQRYAQLEGHLNTT---LASHQIEL---EALRNHQTQQNSQSQEEQKKLKDELNHLMQ 2474

Query: 1154 RSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNL 1213
            R+   EQ      +LQ+   ++  L+  N  L        ++I ++   L +  T   +L
Sbjct: 2475 RNQALEQDRDAYLQLQD---ELDILKAQNASLRQEVDEKSDRIKRVCHTLTEQETRVSDL 2531

Query: 1214 LSTVAELRSSISSAV----DQRGFEIAELWKQHLAQREA-DFQKT-EHELRVQLSAFESK 1267
               +A       S       Q+    A ++++ +  ++A + + T    ++V+   + ++
Sbjct: 2532 EEQLATREQHPPSTAAFFGGQQQPPAAAVFEEIITPKKAYEVEPTPSSAIQVEDDCWGAE 2591

Query: 1268 YEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQE---KYADVINQIE--I 1322
               L +  Q ++     + ++ E+   ++    +KE  L+ + E   K   ++ +++   
Sbjct: 2592 EAALEEKHQQTSSVALERRIS-EKDDYIRQLEMEKERLLQEIVELKVKSGKLLKKLKEYK 2650

Query: 1323 LRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSX 1382
             +SE    + A                  ++T      ++Q +      E+++ LK+   
Sbjct: 2651 TKSETLQRRSASMETSELDLAIQEELNTQIKTLEGRLSELQAEREKESTEKDSLLKRIDV 2710

Query: 1383 XXXXXXXXXXXRV-NDAE-----AKVLELT---HQLELKDSEIYQKTHEYTITLTQRNDE 1433
                       +   D +     AK+ EL     QLE    E  QK  +    +     +
Sbjct: 2711 LVAANERFTEMKERQDVQMEIQVAKIKELNLKLQQLEDWGDESEQKESKPVEQVQPEAVD 2770

Query: 1434 FENVRQQLVEYEKRIEDLTYEKESELAIL-RLKMHENANHYETMQKESE----IERVKLI 1488
               +  ++ E E+ ++DL  + E   A+L   K +         QK+ E    IE++ L+
Sbjct: 2771 VAPLNARVQELEREVQDLKVDNEELQALLDEEKANVEILEKRVQQKDREIQDLIEKIDLL 2830

Query: 1489 EELNVKI-TESVSLNKQ----VAELNKALEEEVAKTNEMQTALENQEIE-IVTLNDEITN 1542
             + +  I T   SLN+Q      +L+  L++ ++K  E+   +E    E +   +++   
Sbjct: 2831 SQDSQTIKTNLESLNQQKSQETEDLSTRLKQLMSKNTELTQQIEKMRTESLFQSSEQEAK 2890

Query: 1543 LQNMVRASSSKIQ 1555
            LQ  V+  S+++Q
Sbjct: 2891 LQEQVQQLSAQLQ 2903



 Score = 40.7 bits (91), Expect = 0.32
 Identities = 146/741 (19%), Positives = 295/741 (39%), Gaps = 92/741 (12%)

Query: 147  LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEK-DQIIEAKNKATTXXXXXXXXXXX 205
            L   I EKD+ +  L+++ + +   I++L+ K  +   ++ E K K+ T           
Sbjct: 2607 LERRISEKDDYIRQLEMEKERLLQEIVELKVKSGKLLKKLKEYKTKSETLQRRSASMETS 2666

Query: 206  XXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKD--IESKDVRISSLEEANKLLEAA 263
                  ++      K  E  ++ E + + EK+   KD  ++  DV +++ E   ++ E  
Sbjct: 2667 ELDLAIQEELNTQIKTLEGRLS-ELQAEREKESTEKDSLLKRIDVLVAANERFTEMKERQ 2725

Query: 264  RFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTE 323
              ++ ++ +K+ +EL                   + +E    E  ++        A + E
Sbjct: 2726 DVQMEIQVAKI-KELNLKLQQLEDWGDESEQKESKPVEQVQPEAVDVAPLN----ARVQE 2780

Query: 324  LTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISR-----KSGRNT 378
            L ++++ L+  N +++     L+ + A +    K V    ++   LI +     +  +  
Sbjct: 2781 LEREVQDLKVDNEELQAL---LDEEKANVEILEKRVQQKDREIQDLIEKIDLLSQDSQTI 2837

Query: 379  ASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXX 438
             + ++S   Q S ET  +D   ++ K  ++K   + Q + K   +  +  SE++      
Sbjct: 2838 KTNLESLNQQKSQET--EDLSTRL-KQLMSKNTELTQQIEKMRTESLFQSSEQEAKLQEQ 2894

Query: 439  XXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNV 498
                     L AQLQ +  +      ++H+G   E      + +E   Q L  EI   N 
Sbjct: 2895 V------QQLSAQLQYKEAE------IVHLGERIEQ-----QAREDQTQSLVQEILAKNQ 2937

Query: 499  KDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIV 558
            +  I  LKS   ++ QL  E      N+    +      +  +K     S++   N+E  
Sbjct: 2938 E--INNLKS---RVQQLEAERQELQHNLTLQITKELASSRPDEKQSPRVSELERLNRE-- 2990

Query: 559  RLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISL 618
             L  E H + Q++  L ++     L L D   G ++E D   K IE+E L  +       
Sbjct: 2991 -LQAEKHQMEQELQVLNDQVLR-SLELEDRMKGTVLELDA--KNIEIEALKTS------- 3039

Query: 619  LESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKEL 678
                       L +L+Q   E   + A  S+ QS     + +   L +QI  LS  + EL
Sbjct: 3040 -----------LELLKQA-SEASGESASSSE-QSTPTAGKSEE-DLRKQIKKLSRERSEL 3085

Query: 679  ALVIENLKLDKEQLYGTIKDLENDK-EDIMNKLQNYIQENMDLTDKLEKMSAEKISELLA 737
                 N ++  EQ       +  ++   +    + ++         +EK   E+I  L  
Sbjct: 3086 E---ANYRITLEQRDAHWSQVVEERGAQVAESWKQHVDMREAEFSVIEKSLREEIDRLQG 3142

Query: 738  KINHEEQSKIQTQF--GIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSL 795
              +    S  Q++    + A ++ ++L I  ++ +L+   +   RL   +       +++
Sbjct: 3143 DGSETPSSSEQSEAVQNMKAALEAQELEIVTLKEQLAIRSAEYARLAAQV-----DPFAV 3197

Query: 796  ERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKN 855
            +  ++ + S  + +  A     +   EL   LA+ M + R +  + LE+E  N       
Sbjct: 3198 KHASNMVTSEPRPQPAAQDGDKVPRSEL--ELALYMIYQRDMRCEELELELRN------- 3248

Query: 856  QILLEENQNLQISLSD-MQQH 875
              LL E  +LQ+ LS+ ++QH
Sbjct: 3249 --LLTERDSLQLRLSNALRQH 3267


>UniRef50_A2DLG0 Cluster: Viral A-type inclusion protein, putative;
            n=1; Trichomonas vaginalis G3|Rep: Viral A-type inclusion
            protein, putative - Trichomonas vaginalis G3
          Length = 3369

 Score =  234 bits (572), Expect = 2e-59
 Identities = 296/1498 (19%), Positives = 657/1498 (43%), Gaps = 118/1498 (7%)

Query: 143  DVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXX 202
            +++    TI EK + +  L  ++   + ++ ++ EKIN  ++  + KN            
Sbjct: 173  EISEKEKTINEKSSKIEELNQQISEKDNSLKEMTEKINNLEEENKQKN-------SRIEE 225

Query: 203  XXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEA 262
                      D + ++  + E     E++  +  + +++    K+  +S L E  K  ++
Sbjct: 226  LQQQLESLRNDDENRINNLYEELSQKESKINELNELMMQQQTGKETILSQLNEQIKEKDS 285

Query: 263  ARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMT 322
               E+    SKL  E+ Q                K  +    EEK E++++ S + + + 
Sbjct: 286  KIGELEENVSKLESEISQKESNINELSSQVSEKDKM-VNDISEEKNELQKQLSDQNSMID 344

Query: 323  ELTKKI-ELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASK 381
            EL ++I EL ++L+    ++  E ++K   + +E +   S  K+    ++ + G     K
Sbjct: 345  ELNEQIKELTDNLSKSTTEST-EKDSKNQELISEKETEISHLKEEISKLTEQHGEK--DK 401

Query: 382  MKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKE-------YVISEKDTX 434
            +     +L+ +   QD + K   + I++L++++     +L +K+       + + EKD  
Sbjct: 402  L---IQELTEQIQTQDINLKQKDSNISELQVLVSQKETELSEKDNSINEFIHKLEEKDLQ 458

Query: 435  XXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEI- 493
                      K++ I +L  +     +  SL  +      + E  + +E    + N+E+ 
Sbjct: 459  IKELNEQLNNKESQINELNAQISD--KENSLQEITDKVHTLEETVQNKETEINQKNEELS 516

Query: 494  -KDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSD 552
             ++  + +L E +   + +I Q N+EI + N  + ++      K   +Q+  D    +  
Sbjct: 517  ERETKINELNEIISQKDSEIQQKNEEISSNNSKIDELNQQISNKENSLQELTDKVHSLET 576

Query: 553  SNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETR 612
             N E      ++  L++ V+E EEE   LQ  +   ++      D   K+ EM      +
Sbjct: 577  KNSE---QETQIDELTKLVSEKEEENNKLQETIQTKETE---IKDKQSKVDEMNQEISDK 630

Query: 613  LKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCS-EIKSVHLEEQID-- 669
             K+I  +  +   L +E      + DE++++++ I+  +   + +   +  +   +ID  
Sbjct: 631  DKSIEEITERVNKLEEENKTKNSQIDEMKEQISSITTNEETAISTLNTQLNNKNNEIDLL 690

Query: 670  --ALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKM 727
               L + + E    I  L     +LY  I +   +  ++  ++ +  QE +D  +KL+ +
Sbjct: 691  HQQLQSKETENEKAINELNDKLNKLYEEIANKNTNITELNEQISSKNQEIVDRDNKLQSL 750

Query: 728  SA------EKISELLAKIN--HEEQSKIQTQFG-IDAKIQERDLYIENIESELSKYKSRI 778
                    E+I E  +KI   ++  SK  ++   +  +I +    IE + +E++   + I
Sbjct: 751  GTELNQKNEEIKEKDSKIGEFNDLVSKKDSEINQLQEEIADISSKIEELNNEIATKDASI 810

Query: 779  CRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVE 838
              L   IA  + +  SL+ +   L S   EK+   S+  ++ DE  + +         V+
Sbjct: 811  LELNNKIAEKDLKIKSLDEEKSSLQSKPAEKENDISDLLVKYDEKCSEI-------EAVQ 863

Query: 839  KQLLEIEHENKELQK-KNQILLEENQNLQISLSDMQQHYNALVEK------ANRTDLAES 891
             +L + + ENKE ++  +Q + E+++ +  S + +      L EK       N  + AE 
Sbjct: 864  SELAKKDKENKEFEELMSQAISEKDEEISKSKNGISSLQEKLAEKEKEINSKNEANTAEK 923

Query: 892  ESTKYQTQLRDLE-SNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKY 950
            E        RD E SNL +   E +  I  K + I   E + N  IE   + +  +NEK 
Sbjct: 924  EENSKLISQRDEEISNLNKSIDELRKEISTKDETISQFESKINELIEEISKKELTINEKE 983

Query: 951  EKNI---EYVTQLEAQLQEYKNNIENLNMNVEEL------NKMNLELIDKHVQKQQTQSP 1001
             K     E +TQ E ++   K   + +   + E+       + ++  +++ VQ ++T+  
Sbjct: 984  TKIAELNEQITQKENEINGLKEAEKVMETKISEIESQLTEKEKSINELEETVQNKETEIN 1043

Query: 1002 DYTEQYI---NEINKLNALLKQKDEEIIALNQKI--NNAQVSYMS-MVSDYESKLAQFTT 1055
               E+      +IN+LN ++ QKD EI   N++I  NN+++  ++  +S+ E+ L + T 
Sbjct: 1044 QKNEELSERETKINELNEIISQKDSEIQQKNEEISSNNSKIDELNQQISNKENSLQELTD 1103

Query: 1056 KL-----ENMEEEMQ--RVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPK 1108
            K+     +N E+E Q   ++K + + ++ N +LQ  ++ ++ +IK+ K++K+  EMN   
Sbjct: 1104 KVHSLETKNSEQETQIEELTKLVSEKEEENNKLQETIQTKETEIKD-KQSKVD-EMNQEI 1161

Query: 1109 TEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTEL 1168
            ++      +IE +++  N ++            +K Q       E + +   + +LN + 
Sbjct: 1162 SDK---DKSIEEITERVNKLEEENKTKNSQIDEMKEQISSITTNEETAISTLNTQLNNKN 1218

Query: 1169 QECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAV 1228
             E      QL++  TE+   +    E+I++  + L+   TE       + EL   IS   
Sbjct: 1219 NEIDLLHQQLQSKETEIKQLN----EEISERNNALQTKETEIKEKELKINELNDIISKKE 1274

Query: 1229 DQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETN---K 1285
            +++  E   L  +++ +   + +   +EL  +L   E + +Q   S +   Q  T+   K
Sbjct: 1275 EEKA-EKESLLNENINKLNTERESQINELSEKLLKLEEQLKQETLSNEDMKQTNTSLSQK 1333

Query: 1286 IVTME-QVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKV---AFXXXXXXX 1341
            I  M  Q++   ++LQ+  + +  L  + +D    +  L+ EI+++ V            
Sbjct: 1334 IDEMAFQLSDKTSQLQELNQQITVLSSQISDKDKTVNDLQEEIKEKSVQNEENSRIINDL 1393

Query: 1342 XXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAK 1401
                     D++++++  K ++++    INE  A+L+                 N   ++
Sbjct: 1394 KEFIKQYDEDIKSKDEKIKSIEQEKDAKINEIKAELETKETENSQLFGNISELQNMLSSR 1453

Query: 1402 VLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAI 1461
              E    +   ++++ Q+      +L+++ ++F ++   L +Y++ + +  + KE E   
Sbjct: 1454 DSEY-ETVCSDNNKLKQEIEALKSSLSEKENDFASI---LSKYDEEVSN--HNKEVE--- 1504

Query: 1462 LRLKMHENANHYETMQKESEIERVKL-IEELNVKITESVSLNKQVAELNKALEEEVAKTN 1520
              L   +  N  +  +KE+EI  +K  IE L   + E    + ++++ ++A+++      
Sbjct: 1505 -ELTKKDEENKQQVDEKENEISNLKKEIENLKSSLNEK---DNEISQNSQAIDDSSKHVQ 1560

Query: 1521 EMQ----TALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDN 1574
            E+Q      L+ ++ EI   ++E++NL+ ++    S+I   +    +  + ++E++ N
Sbjct: 1561 ELQHQFDEDLKQKQEEISAKDEELSNLKKVLEEEKSEITSSLQEKDELIKQKEEEISN 1618



 Score =  233 bits (571), Expect = 2e-59
 Identities = 258/1153 (22%), Positives = 528/1153 (45%), Gaps = 93/1153 (8%)

Query: 485  LKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTI 544
            + QE++D  KD +++++ E++   EE+    N +ID   + +  + +N +  +  +   +
Sbjct: 1    MNQEISD--KDKSIEEITERVNKLEEENKTKNSQIDEMKEQISSITTNEETAISTLNTQL 58

Query: 545  DNFSKVSDSNKEIVRLTE-ELHHLSQKVAELEEEKGNLQLHLVDY-----DSGRMIESDV 598
            +N +   D   + ++  E E+  L++ V+E E+    LQ  L        ++   I+  +
Sbjct: 59   NNKNNEIDLLHQQLQSKETEISKLTENVSEREKSFTELQEQLEKAKQEHEETISEIKLKL 118

Query: 599  YKKMIEMENLAETRLKAISLLES---QKFDLVQELHILQQKYDEVEDKLADI-SQLQSDQ 654
              K  E+  L  T  +  S LE    Q  +L + L   +   +E+ D L+ +  ++   +
Sbjct: 119  ESKDNEINELNSTLSQIRSELEQTNKQNTELTETLSQKESNINEINDNLSKLREEISEKE 178

Query: 655  VCSEIKSVHLEE---QIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQ 711
                 KS  +EE   QI     S KE+   I NL+ + +Q    I++L+   E + N  +
Sbjct: 179  KTINEKSSKIEELNQQISEKDNSLKEMTEKINNLEEENKQKNSRIEELQQQLESLRNDDE 238

Query: 712  NYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESEL 771
            N I    +L ++L +  + KI+EL   +  ++  K      ++ +I+E+D  I  +E  +
Sbjct: 239  NRIN---NLYEELSQKES-KINELNELMMQQQTGKETILSQLNEQIKEKDSKIGELEENV 294

Query: 772  SKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLM 831
            SK +S I + E +I  +  +    ++  + +     E QK  S+     DEL  ++  L 
Sbjct: 295  SKLESEISQKESNINELSSQVSEKDKMVNDISEEKNELQKQLSDQNSMIDELNEQIKELT 354

Query: 832  DHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTD-LAE 890
            D+       L +   E+ E   KNQ L+ E +     +S +++  + L E+    D L +
Sbjct: 355  DN-------LSKSTTESTEKDSKNQELISEKET---EISHLKEEISKLTEQHGEKDKLIQ 404

Query: 891  SESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLE---IEFNTQIESAIRDKKVLN 947
              + + QTQ  +L+     I+ E Q L+ QK+ E+ + +    EF  ++E      K LN
Sbjct: 405  ELTEQIQTQDINLKQKDSNIS-ELQVLVSQKETELSEKDNSINEFIHKLEEKDLQIKELN 463

Query: 948  EKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQY 1007
            E+       + +L AQ+ + +N+++ +   V       LE   ++ + +  Q  +   + 
Sbjct: 464  EQLNNKESQINELNAQISDKENSLQEITDKVH-----TLEETVQNKETEINQKNEELSER 518

Query: 1008 INEINKLNALLKQKDEEIIALNQKI--NNAQVSYMS-MVSDYESKLAQFTTKL-----EN 1059
              +IN+LN ++ QKD EI   N++I  NN+++  ++  +S+ E+ L + T K+     +N
Sbjct: 519  ETKINELNEIISQKDSEIQQKNEEISSNNSKIDELNQQISNKENSLQELTDKVHSLETKN 578

Query: 1060 MEEEMQ--RVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISST 1117
             E+E Q   ++K + + ++ N +LQ  ++ ++ +IK+ K++K+  EMN   ++      +
Sbjct: 579  SEQETQIDELTKLVSEKEEENNKLQETIQTKETEIKD-KQSKVD-EMNQEISDK---DKS 633

Query: 1118 IEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQ 1177
            IE +++  N ++            +K Q       E + +    + LNT+L     K  +
Sbjct: 634  IEEITERVNKLEEENKTKNSQIDEMKEQISSITTNEETAI----STLNTQLN---NKNNE 686

Query: 1178 LETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISS---AVDQRGFE 1234
            ++ L+ +L   +  N++ IN+L  KL +L  E  N  + + EL   ISS    +  R  +
Sbjct: 687  IDLLHQQLQSKETENEKAINELNDKLNKLYEEIANKNTNITELNEQISSKNQEIVDRDNK 746

Query: 1235 IAELWKQHLAQREADFQKTEH---ELRVQLSAFESKYEQL---LDSVQSSTQEETNKIVT 1288
            +  L  + L Q+  + ++ +    E    +S  +S+  QL   +  + S  +E  N+I T
Sbjct: 747  LQSLGTE-LNQKNEEIKEKDSKIGEFNDLVSKKDSEINQLQEEIADISSKIEELNNEIAT 805

Query: 1289 ME-QVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXX 1347
             +  +  L NK+ +K+  +++L E+ + + ++     ++I D  V +             
Sbjct: 806  KDASILELNNKIAEKDLKIKSLDEEKSSLQSKPAEKENDISDLLVKYDEKCSEIEAVQSE 865

Query: 1348 XXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDA-EAKVLELT 1406
                 + EN+ ++++  Q+I   +EE ++ K                +N   EA   E  
Sbjct: 866  LAKKDK-ENKEFEELMSQAISEKDEEISKSKNGISSLQEKLAEKEKEINSKNEANTAEKE 924

Query: 1407 HQLEL---KDSEI------YQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKES 1457
               +L   +D EI        +  +   T  +   +FE+   +L+E   + E    EKE+
Sbjct: 925  ENSKLISQRDEEISNLNKSIDELRKEISTKDETISQFESKINELIEEISKKELTINEKET 984

Query: 1458 ELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVA 1517
            ++A L  ++ +  N    +++  ++   K I E+  ++TE     K + EL + ++ +  
Sbjct: 985  KIAELNEQITQKENEINGLKEAEKVMETK-ISEIESQLTEK---EKSINELEETVQNKET 1040

Query: 1518 KTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMN 1577
            + N+    L  +E +I  LN+ I+   + ++  + +I  + S   +  Q    Q+ N  N
Sbjct: 1041 EINQKNEELSERETKINELNEIISQKDSEIQQKNEEISSNNSKIDELNQ----QISNKEN 1096

Query: 1578 --KELLDAVPRAE 1588
              +EL D V   E
Sbjct: 1097 SLQELTDKVHSLE 1109



 Score =  228 bits (558), Expect = 8e-58
 Identities = 312/1566 (19%), Positives = 683/1566 (43%), Gaps = 154/1566 (9%)

Query: 144  VTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXX 203
            ++ L+  IKEKD+ +  L+  +  +E+ I   +  INE    +  K+K            
Sbjct: 273  LSQLNEQIKEKDSKIGELEENVSKLESEISQKESNINELSSQVSEKDKMVNDISEEKNEL 332

Query: 204  XXXXX---XXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSL-EEANKL 259
                       ++  +Q+ ++ +N      E  ++  +  + I  K+  IS L EE +KL
Sbjct: 333  QKQLSDQNSMIDELNEQIKELTDNLSKSTTESTEKDSKNQELISEKETEISHLKEEISKL 392

Query: 260  LEAARFEISLEHSKLAQEL-EQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEK-GSLE 317
             E        E  KL QEL EQ              +++  +  S +++TE+ EK  S+ 
Sbjct: 393  TEQHG-----EKDKLIQELTEQIQTQDINLKQKDSNISELQVLVS-QKETELSEKDNSIN 446

Query: 318  --IANMTELTKKI-ELLEHLN---CQIRQTNKEL---ENKLATMGTESKAVSSPSKKGSP 368
              I  + E   +I EL E LN    QI + N ++   EN L  +  +   +    +    
Sbjct: 447  EFIHKLEEKDLQIKELNEQLNNKESQINELNAQISDKENSLQEITDKVHTLEETVQNKET 506

Query: 369  LISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVI 428
             I++K+     S+ ++  ++L+     +D++ +    EI+     I  LN+ + +KE  +
Sbjct: 507  EINQKN--EELSERETKINELNEIISQKDSEIQQKNEEISSNNSKIDELNQQISNKENSL 564

Query: 429  SEKDTXXXXXXXXXXGKDTLIAQL-QLEHQQHMEGPSLIH-VGTNTEDVNEIAKVQEQLK 486
             E              ++T I +L +L  ++  E   L   + T   ++ +     +++ 
Sbjct: 565  QELTDKVHSLETKNSEQETQIDELTKLVSEKEEENNKLQETIQTKETEIKDKQSKVDEMN 624

Query: 487  QELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKL--------- 537
            QE++D  KD +++++ E++   EE+    N +ID   + +  + +N +  +         
Sbjct: 625  QEISD--KDKSIEEITERVNKLEEENKTKNSQIDEMKEQISSITTNEETAISTLNTQLNN 682

Query: 538  ---------KQMQ-KTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVD 587
                     +Q+Q K  +N   +++ N ++ +L EE+ + +  + EL E+  +    +VD
Sbjct: 683  KNNEIDLLHQQLQSKETENEKAINELNDKLNKLYEEIANKNTNITELNEQISSKNQEIVD 742

Query: 588  YDSG-RMIESDVYKKMIEMENLAETRLKAISLLESQKFD----LVQELHILQQKYDEVED 642
             D+  + + +++ +K  E++   ++++   + L S+K      L +E+  +  K +E+ +
Sbjct: 743  RDNKLQSLGTELNQKNEEIKE-KDSKIGEFNDLVSKKDSEINQLQEEIADISSKIEELNN 801

Query: 643  KLA--DISQLQSDQVCSE--IKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTI-- 696
            ++A  D S L+ +   +E  +K   L+E+  +L +   E    I +L +  ++    I  
Sbjct: 802  EIATKDASILELNNKIAEKDLKIKSLDEEKSSLQSKPAEKENDISDLLVKYDEKCSEIEA 861

Query: 697  -------KDLENDK-EDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQ 748
                   KD EN + E++M++  +   E +  +        EK++E   +IN + ++   
Sbjct: 862  VQSELAKKDKENKEFEELMSQAISEKDEEISKSKNGISSLQEKLAEKEKEINSKNEANTA 921

Query: 749  TQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQE 808
             +      I +RD  I N+   + + +  I   +E+I+  E +   L  +  +    + E
Sbjct: 922  EKEENSKLISQRDEEISNLNKSIDELRKEISTKDETISQFESKINELIEEISKKELTINE 981

Query: 809  KQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQIS 868
            K+   +E   Q  +  N +  L + ++V+E ++ EIE +  E +K    L E  QN +  
Sbjct: 982  KETKIAELNEQITQKENEINGLKEAEKVMETKISEIESQLTEKEKSINELEETVQNKETE 1041

Query: 869  LSDMQQHYNALVEKANR-TDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIED 927
            ++   +  +    K N   ++   + ++ Q +  ++ SN  +I   +Q  I  K+  +++
Sbjct: 1042 INQKNEELSERETKINELNEIISQKDSEIQQKNEEISSNNSKIDELNQQ-ISNKENSLQE 1100

Query: 928  LEIEF------NTQIESAIRD-KKVLNEKYEKN---IEYVTQLEAQLQEYKNNIENLNMN 977
            L  +       N++ E+ I +  K+++EK E+N    E +   E ++++ ++ ++ +N  
Sbjct: 1101 LTDKVHSLETKNSEQETQIEELTKLVSEKEEENNKLQETIQTKETEIKDKQSKVDEMNQE 1160

Query: 978  VEELNKMNLELIDKHVQK-------QQTQSPDYTEQY----INE---INKLNALLKQKDE 1023
            + + +K ++E I + V K       + +Q  +  EQ      NE   I+ LN  L  K+ 
Sbjct: 1161 ISDKDK-SIEEITERVNKLEEENKTKNSQIDEMKEQISSITTNEETAISTLNTQLNNKNN 1219

Query: 1024 EIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSK--QLLDSKQH---- 1077
            EI  L+Q++ + +     +  +   +     TK   ++E+  ++++   ++  K+     
Sbjct: 1220 EIDLLHQQLQSKETEIKQLNEEISERNNALQTKETEIKEKELKINELNDIISKKEEEKAE 1279

Query: 1078 -----NEELQILVREQDDQIKELKETKLTFEMNIP---------KTEGMIISSTIEPM-- 1121
                 NE +  L  E++ QI EL E  L  E  +          K     +S  I+ M  
Sbjct: 1280 KESLLNENINKLNTERESQINELSEKLLKLEEQLKQETLSNEDMKQTNTSLSQKIDEMAF 1339

Query: 1122 --SDDANNVDXXXXXXXXXXXXLK-----VQEEEEFIQERSVLQEQSAKLNTELQECYTK 1174
              SD  + +             +      V + +E I+E+SV  E+++++  +L+E   +
Sbjct: 1340 QLSDKTSQLQELNQQITVLSSQISDKDKTVNDLQEEIKEKSVQNEENSRIINDLKEFIKQ 1399

Query: 1175 IIQ-LETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISS------- 1226
              + +++ + ++   +     +IN++K++LE   TEN  L   ++EL++ +SS       
Sbjct: 1400 YDEDIKSKDEKIKSIEQEKDAKINEIKAELETKETENSQLFGNISELQNMLSSRDSEYET 1459

Query: 1227 --AVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQ---E 1281
              + + +  +  E  K  L+++E DF     +   ++S    + E+L    + + Q   E
Sbjct: 1460 VCSDNNKLKQEIEALKSSLSEKENDFASILSKYDEEVSNHNKEVEELTKKDEENKQQVDE 1519

Query: 1282 ETNKIVTM-EQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIED------EKVA- 1333
            + N+I  + +++ +L++ L +K+  +    +   D    ++ L+ + ++      E+++ 
Sbjct: 1520 KENEISNLKKEIENLKSSLNEKDNEISQNSQAIDDSSKHVQELQHQFDEDLKQKQEEISA 1579

Query: 1334 ----FXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXX 1389
                                  L+ +++  KQ +E+ I N+N    + +K          
Sbjct: 1580 KDEELSNLKKVLEEEKSEITSSLQEKDELIKQ-KEEEISNLNSVIQEKEKVIASLQGKVN 1638

Query: 1390 XXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIE 1449
                 VN  EA+++ L    + K+ EI     +   T+ ++  E   ++  + + +K I 
Sbjct: 1639 DENNEVNAKEAEIVSLNEIQKKKEEEISSLQEKLNSTIAEKEKEISELQSSINDKDKEIS 1698

Query: 1450 DLTYEKESELAILRLKMHE-NANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAEL 1508
             L  +   E   +  K  E ++ + +  QK+ EI  +K   E+  K  E   L   V E 
Sbjct: 1699 SLQEKVNIENNDVNTKETEISSLNDQLKQKDEEINNLK--SEIKEKFEELSKLQSLVNEN 1756

Query: 1509 NKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGR 1568
             + +     K N  +    N+E E+    +EI+NL   ++    +I       +++   +
Sbjct: 1757 EQVIVSLQEKVNSDEI---NKENELKMKEEEISNLNGSIQEKEKEISLLKENFNNSLAQK 1813

Query: 1569 DEQLDN 1574
            DE++ N
Sbjct: 1814 DEEISN 1819



 Score =  207 bits (506), Expect = 2e-51
 Identities = 280/1494 (18%), Positives = 637/1494 (42%), Gaps = 103/1494 (6%)

Query: 169  ETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAM 228
            + +I ++ E++N+ ++  + KN                          Q+         +
Sbjct: 9    DKSIEEITERVNKLEEENKTKNSQIDEMKEQISSITTNEETAISTLNTQLNNKNNEIDLL 68

Query: 229  EAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXX 288
              + + ++  + K  E+   R  S  E  + LE A+ E     S++  +LE         
Sbjct: 69   HQQLQSKETEISKLTENVSEREKSFTELQEQLEKAKQEHEETISEIKLKLESKDNEINEL 128

Query: 289  XXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENK 348
                  + +  +E + ++ TE+ E  S + +N+ E+   +  L     +  +T  E  +K
Sbjct: 129  NSTLSQI-RSELEQTNKQNTELTETLSQKESNINEINDNLSKLREEISEKEKTINEKSSK 187

Query: 349  LATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINK--NE 406
            +  +  +     +  K+ +  I+     N     +    Q   E+L  D + +IN    E
Sbjct: 188  IEELNQQISEKDNSLKEMTEKINNLEEENKQKNSRIEELQQQLESLRNDDENRINNLYEE 247

Query: 407  IAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLI 466
            +++ E  I  LN+ ++ ++   + K+T           KD+ I +L+ E+   +E     
Sbjct: 248  LSQKESKINELNELMMQQQ---TGKETILSQLNEQIKEKDSKIGELE-ENVSKLES---- 299

Query: 467  HVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNM 526
             +     ++NE++    +  + +ND  ++ N  +L ++L      I +LN++I     N+
Sbjct: 300  EISQKESNINELSSQVSEKDKMVNDISEEKN--ELQKQLSDQNSMIDELNEQIKELTDNL 357

Query: 527  IKVKSNHKLKLKQMQKTI-DNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHL 585
             K  +    K  + Q+ I +  +++S   +EI +LTE+     + + EL E+     ++L
Sbjct: 358  SKSTTESTEKDSKNQELISEKETEISHLKEEISKLTEQHGEKDKLIQELTEQIQTQDINL 417

Query: 586  VDYDSG----RMIESDVYKKMIEMEN--------LAETRLKAISL------LESQKFDLV 627
               DS     +++ S    ++ E +N        L E  L+   L       ESQ  +L 
Sbjct: 418  KQKDSNISELQVLVSQKETELSEKDNSINEFIHKLEEKDLQIKELNEQLNNKESQINELN 477

Query: 628  QELHILQQKYDEVEDKLADISQ-LQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLK 686
             ++   +    E+ DK+  + + +Q+ +     K+  L E+   ++   + ++     ++
Sbjct: 478  AQISDKENSLQEITDKVHTLEETVQNKETEINQKNEELSERETKINELNEIISQKDSEIQ 537

Query: 687  LDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEK---ISELLAKINHEE 743
               E++      ++   + I NK +N +QE  D    LE  ++E+   I EL   ++ +E
Sbjct: 538  QKNEEISSNNSKIDELNQQISNK-ENSLQELTDKVHSLETKNSEQETQIDELTKLVSEKE 596

Query: 744  QSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLG 803
            +   + Q      IQ ++  I++ +S++ +    I   ++SI  + +R   LE +     
Sbjct: 597  EENNKLQ----ETIQTKETEIKDKQSKVDEMNQEISDKDKSIEEITERVNKLEEENKTKN 652

Query: 804  SYLQEKQKAYSEYTIQEDELVNRLAVLMDHDR----VVEKQLLEIEHENK----ELQKKN 855
            S + E ++  S  T  E+  ++ L   +++      ++ +QL   E EN+    EL  K 
Sbjct: 653  SQIDEMKEQISSITTNEETAISTLNTQLNNKNNEIDLLHQQLQSKETENEKAINELNDKL 712

Query: 856  QILLEENQNLQISLSDMQQHYNA----LVEKANRTDLAESESTKYQTQLRDLESNLKR-- 909
              L EE  N   +++++ +  ++    +V++ N+     +E  +   ++++ +S +    
Sbjct: 713  NKLYEEIANKNTNITELNEQISSKNQEIVDRDNKLQSLGTELNQKNEEIKEKDSKIGEFN 772

Query: 910  -ITHEHQTLIVQKKKEIEDLEIEFNT-QIESAIRDKKVL---NEKYEKNI------EYVT 958
             +  +  + I Q ++EI D+  +      E A +D  +L   N+  EK++      E  +
Sbjct: 773  DLVSKKDSEINQLQEEIADISSKIEELNNEIATKDASILELNNKIAEKDLKIKSLDEEKS 832

Query: 959  QLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALL 1018
             L+++  E +N+I +L +  +E     +E +   + K+  ++ ++ E     I++ +  +
Sbjct: 833  SLQSKPAEKENDISDLLVKYDE-KCSEIEAVQSELAKKDKENKEFEELMSQAISEKDEEI 891

Query: 1019 KQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHN 1078
             +    I +L +K+   +    S      ++  + +  +   +EE+  ++K + + ++  
Sbjct: 892  SKSKNGISSLQEKLAEKEKEINSKNEANTAEKEENSKLISQRDEEISNLNKSIDELRKEI 951

Query: 1079 EELQILVREQDDQIKELKETKLTFEMNIPKTEGMI--ISSTIEPMSDDANNVDXXXXXXX 1136
                  + + + +I EL E     E+ I + E  I  ++  I    ++ N +        
Sbjct: 952  STKDETISQFESKINELIEEISKKELTINEKETKIAELNEQITQKENEINGLKEAEKVME 1011

Query: 1137 XXXXXLKVQ--EEEEFIQE-RSVLQEQSAKLNT---ELQECYTKIIQLETLNTELTGHDV 1190
                 ++ Q  E+E+ I E    +Q +  ++N    EL E  TKI +L  + ++      
Sbjct: 1012 TKISEIESQLTEKEKSINELEETVQNKETEINQKNEELSERETKINELNEIISQKDSEIQ 1071

Query: 1191 VNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADF 1250
               E+I+   SK+++LN +  N  +++ EL   + S   +   +  ++  + L +  ++ 
Sbjct: 1072 QKNEEISSNNSKIDELNQQISNKENSLQELTDKVHSLETKNSEQETQI--EELTKLVSEK 1129

Query: 1251 QKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQD----KEEHL 1306
            ++  ++L+  +   E++ +     V    QE ++K  ++E++T   NKL++    K   +
Sbjct: 1130 EEENNKLQETIQTKETEIKDKQSKVDEMNQEISDKDKSIEEITERVNKLEEENKTKNSQI 1189

Query: 1307 RNLQEKYADVINQ----IEILRSEIEDE--KVAFXXXXXXXXXXXXXXXXDLRTENQSYK 1360
              ++E+ + +       I  L +++ ++  ++                  +  +E  +  
Sbjct: 1190 DEMKEQISSITTNEETAISTLNTQLNNKNNEIDLLHQQLQSKETEIKQLNEEISERNNAL 1249

Query: 1361 QMQEQSI----LNINEENAQLKKSSXXXXXXXXXXXXRVN----DAEAKVLELTHQLELK 1412
            Q +E  I    L INE N  + K               +N    + E+++ EL+ +L   
Sbjct: 1250 QTKETEIKEKELKINELNDIISKKEEEKAEKESLLNENINKLNTERESQINELSEKLLKL 1309

Query: 1413 DSEIYQKT---HEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHEN 1469
            + ++ Q+T    +   T T  + + + +  QL +   ++++L  ++ + L+       + 
Sbjct: 1310 EEQLKQETLSNEDMKQTNTSLSQKIDEMAFQLSDKTSQLQELN-QQITVLSSQISDKDKT 1368

Query: 1470 ANHYETMQKESEI---ERVKLIEELNVKITESVSLNKQVAELNKALEEEV-AKTNEMQTA 1525
             N  +   KE  +   E  ++I +L   I +     K   E  K++E+E  AK NE++  
Sbjct: 1369 VNDLQEEIKEKSVQNEENSRIINDLKEFIKQYDEDIKSKDEKIKSIEQEKDAKINEIKAE 1428

Query: 1526 LENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKE 1579
            LE +E E   L   I+ LQNM+ +  S+ +   S  +  KQ  +    +   KE
Sbjct: 1429 LETKETENSQLFGNISELQNMLSSRDSEYETVCSDNNKLKQEIEALKSSLSEKE 1482



 Score =  200 bits (488), Expect = 3e-49
 Identities = 263/1338 (19%), Positives = 602/1338 (44%), Gaps = 112/1338 (8%)

Query: 298  QSIEPSCEEKTEIEEKGSLEIANMTELTKKIE-LLEHLNCQIRQTNKELENKLATMGTES 356
            +SIE   E   ++EE+   + + + E+ ++I  +  +    I   N +L NK   +    
Sbjct: 10   KSIEEITERVNKLEEENKTKNSQIDEMKEQISSITTNEETAISTLNTQLNNKNNEIDLLH 69

Query: 357  KAVSSPSKKGSPLISRKSGRNTA-SKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQ 415
            + + S   + S L    S R  + ++++    +   E  +++T  +I K ++   +  I 
Sbjct: 70   QQLQSKETEISKLTENVSEREKSFTELQEQLEKAKQE--HEETISEI-KLKLESKDNEIN 126

Query: 416  SLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDV 475
             LN  L      + + +            K++ I ++     +  E      +    + +
Sbjct: 127  ELNSTLSQIRSELEQTNKQNTELTETLSQKESNINEINDNLSKLRE-----EISEKEKTI 181

Query: 476  NEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKL 535
            NE +   E+L Q++++  KD ++K++ EK+ + EE+  Q N  I+   + +  ++++ + 
Sbjct: 182  NEKSSKIEELNQQISE--KDNSLKEMTEKINNLEEENKQKNSRIEELQQQLESLRNDDEN 239

Query: 536  KLKQMQKTIDNF-SKVSDSNKEIVRLTEE----LHHLSQKVAELEEEKGNLQLHLVDYDS 590
            ++  + + +    SK+++ N+ +++        L  L++++ E + + G L+      ++
Sbjct: 240  RINNLYEELSQKESKINELNELMMQQQTGKETILSQLNEQIKEKDSKIGELE------EN 293

Query: 591  GRMIESDVYKK---MIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADI 647
               +ES++ +K   + E+ +    + K ++ +  +K +L ++L       DE+ +++ ++
Sbjct: 294  VSKLESEISQKESNINELSSQVSEKDKMVNDISEEKNELQKQLSDQNSMIDELNEQIKEL 353

Query: 648  SQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIM 707
            +   S       +     +++  +S  + E++ + E +    EQ          +K+ ++
Sbjct: 354  TDNLSKSTTESTEKDSKNQEL--ISEKETEISHLKEEISKLTEQ--------HGEKDKLI 403

Query: 708  NKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENI 767
             +L   IQ   D+  K +  +  ++  L+++   E   K  +      K++E+DL I+ +
Sbjct: 404  QELTEQIQ-TQDINLKQKDSNISELQVLVSQKETELSEKDNSINEFIHKLEEKDLQIKEL 462

Query: 768  ESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRL 827
              +L+  +S+I  L   I+   D+  SL+   D++ +  +  Q   +E   + +EL  R 
Sbjct: 463  NEQLNNKESQINELNAQIS---DKENSLQEITDKVHTLEETVQNKETEINQKNEELSERE 519

Query: 828  AVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTD 887
              + + + ++ ++  EI+ +N+E+   N  + E NQ +    + +Q+    L +K +  +
Sbjct: 520  TKINELNEIISQKDSEIQQKNEEISSNNSKIDELNQQISNKENSLQE----LTDKVHSLE 575

Query: 888  LAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEI---EFNTQIESAIRDKK 944
               SE      +L  L S  +   ++ Q  I  K+ EI+D +    E N +I    +  +
Sbjct: 576  TKNSEQETQIDELTKLVSEKEEENNKLQETIQTKETEIKDKQSKVDEMNQEISDKDKSIE 635

Query: 945  VLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEE-LNKMNLELIDKHVQ----KQQTQ 999
             + E+  K  E      +Q+ E K  I ++  N E  ++ +N +L +K+ +     QQ Q
Sbjct: 636  EITERVNKLEEENKTKNSQIDEMKEQISSITTNEETAISTLNTQLNNKNNEIDLLHQQLQ 695

Query: 1000 SPDY-TEQYINEIN-KLNALLKQ---KDEEIIALNQKINNAQVSYMSMVSDYESKLAQFT 1054
            S +   E+ INE+N KLN L ++   K+  I  LN++I++        + D ++KL    
Sbjct: 696  SKETENEKAINELNDKLNKLYEEIANKNTNITELNEQISSKNQE----IVDRDNKLQSLG 751

Query: 1055 TKLENMEEEMQRVSKQL-----LDSKQHNE--ELQILVREQDDQIKELKETKLTFEMNIP 1107
            T+L    EE++    ++     L SK+ +E  +LQ  + +   +I+EL     T + +I 
Sbjct: 752  TELNQKNEEIKEKDSKIGEFNDLVSKKDSEINQLQEEIADISSKIEELNNEIATKDASIL 811

Query: 1108 KTEGMIISST--IEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQE--QSAK 1163
            +    I      I+ + ++ +++             L V+ +E+  +  +V  E  +  K
Sbjct: 812  ELNNKIAEKDLKIKSLDEEKSSLQSKPAEKENDISDLLVKYDEKCSEIEAVQSELAKKDK 871

Query: 1164 LNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSS 1223
             N E +E  ++ I  +      + + + + ++  +L  K +++N++N+   +  AE   +
Sbjct: 872  ENKEFEELMSQAISEKDEEISKSKNGISSLQE--KLAEKEKEINSKNE---ANTAEKEEN 926

Query: 1224 ISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQS---STQ 1280
             S  + QR  EI+ L K     R+    K E      +S FESK  +L++ +     +  
Sbjct: 927  -SKLISQRDEEISNLNKSIDELRKEISTKDE-----TISQFESKINELIEEISKKELTIN 980

Query: 1281 EETNKIVTM-EQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXX 1339
            E+  KI  + EQ+T  +N++   +E  + ++ K +++ +Q+      I +E         
Sbjct: 981  EKETKIAELNEQITQKENEINGLKEAEKVMETKISEIESQLTEKEKSI-NELEETVQNKE 1039

Query: 1340 XXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAE 1399
                       +  T+     ++  Q    I ++N ++  ++            + N  +
Sbjct: 1040 TEINQKNEELSERETKINELNEIISQKDSEIQQKNEEISSNNSKIDELNQQISNKENSLQ 1099

Query: 1400 AKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESEL 1459
             ++ +  H LE K+SE   +  E T  ++++ +E   +++ +   E  I+D    K+S++
Sbjct: 1100 -ELTDKVHSLETKNSEQETQIEELTKLVSEKEEENNKLQETIQTKETEIKD----KQSKV 1154

Query: 1460 AILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKT 1519
                 +M++     E   K+  IE +   E +N    E+ + N Q+ E+ + +      T
Sbjct: 1155 D----EMNQ-----EISDKDKSIEEIT--ERVNKLEEENKTKNSQIDEMKEQISS--ITT 1201

Query: 1520 NEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQ---KHVSFASDTKQGRDEQLDNTM 1576
            NE +TA+     ++   N+EI  L   +++  ++I+   + +S  ++  Q ++ ++    
Sbjct: 1202 NE-ETAISTLNTQLNNKNNEIDLLHQQLQSKETEIKQLNEEISERNNALQTKETEIKEKE 1260

Query: 1577 NK--ELLDAVPRAELDLA 1592
             K  EL D + + E + A
Sbjct: 1261 LKINELNDIISKKEEEKA 1278



 Score =  193 bits (470), Expect = 4e-47
 Identities = 320/1544 (20%), Positives = 664/1544 (43%), Gaps = 164/1544 (10%)

Query: 151  IKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXX 210
            IK+K+  +S L   ++  E  I  LQ K+N+++  + AK                     
Sbjct: 1609 IKQKEEEISNLNSVIQEKEKVIASLQGKVNDENNEVNAKEAEIVSLNEIQ---------- 1658

Query: 211  XEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEA----NKLLEAARFE 266
             +  +++++ +QE   +  AE + E   L   I  KD  ISSL+E     N  +     E
Sbjct: 1659 -KKKEEEISSLQEKLNSTIAEKEKEISELQSSINDKDKEISSLQEKVNIENNDVNTKETE 1717

Query: 267  ISLEHSKLAQELEQXXXXXXXXXXXXXXLAK-QSIEPSCEEK-TEIEEK-GSLEIANMTE 323
            IS  + +L Q+ E+              L+K QS+    E+    ++EK  S EI    E
Sbjct: 1718 ISSLNDQLKQKDEEINNLKSEIKEKFEELSKLQSLVNENEQVIVSLQEKVNSDEINKENE 1777

Query: 324  LTKKIELLEHLNCQIRQTNKEL----ENKLATMGTESKAVSSPSKKGSPLISRKSGRNTA 379
            L  K E + +LN  I++  KE+    EN   ++  + + +S+  K    L   KSG    
Sbjct: 1778 LKMKEEEISNLNGSIQEKEKEISLLKENFNNSLAQKDEEISNLKKV---LEEEKSG--IT 1832

Query: 380  SKMKSPWSQLSSETLNQDTDKKINKNEIA-----KLEMVIQS------LNKDLVDKEYVI 428
            S ++   S+L SE   +D  +K  + EI      KLE++ Q       LN  L +   ++
Sbjct: 1833 SSLQEQISKLQSEIKERDEIQKKKEEEIQTLSNEKLELLKQKEEEINVLNSKLNESVELL 1892

Query: 429  SEKD---TXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQ- 484
             +K+               K+  I++LQ E         L       E +NE  K +++ 
Sbjct: 1893 KQKEGDNENNDKISEIRQQKEKEISELQSEINSLKN--ELSANKEEMEKLNETIKERDEE 1950

Query: 485  ---LKQELNDEIKDVN-----VKDLIEKLK-------------SAEEQITQLNDEIDAAN 523
               +KQ+ +D+  +VN     + D+ +KL              S E ++      I   +
Sbjct: 1951 ISSIKQKADDDKSEVNSISNILSDIKQKLSNQTQESIKEGRVFSKEREVPDEETNISQLD 2010

Query: 524  KNMIKVKSNHKLKLKQMQKTIDNF--SKVSDSNKEIVRLTEELHHLSQKVAELEEEKG-- 579
             + IK K +  +K +++ + +D    ++ +D    +  L+E +  +   + EL++E    
Sbjct: 2011 YSPIKSKPSEVVKSREVIELVDEDEGNETNDIRSTVEYLSETIDEMQANIEELKKENAKK 2070

Query: 580  ----------NLQLHLVDYDSGRMIESDVYKKMIEMEN----LAETRLKAISLLESQKFD 625
                      N QL ++  DS  +  +   + M+ M N    L E   K +    SQ  D
Sbjct: 2071 SQEKQSLIYQNQQLRIL-LDSAEIEMNKKSQGMMTMMNDKNGLIENLTKELQTTRSQLND 2129

Query: 626  LVQE-LHILQQKYDEVEDKLADISQLQSDQVC-SEIKSVHLEEQIDALSASKKELALVIE 683
            + Q+ ++ +QQ+    + ++  ++ L S ++  +E        Q DA++ + +E   +I 
Sbjct: 2130 IKQQAVYQMQQQKSFDDQEIQRLNGLISQKLSENEQMRQQFNLQADAMNKTIQEKDEMIN 2189

Query: 684  NLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEE 743
             +K    +L        N+K +  + LQN  +EN +   + E    +  S+L   I + +
Sbjct: 2190 QIKTRANKLL-------NEKLNENSNLQNLQKENEEKLSQKENELNQIKSQLNTVIQNAQ 2242

Query: 744  Q--SKIQTQ-FGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKAD 800
               S +Q +   I+ K+++++  I+N++  L+   S     E+S++++E     LE+   
Sbjct: 2243 SQISALQNEKIAIENKMKQQEDLIQNMK--LANESS-----EQSLSLLEGENSKLEQICA 2295

Query: 801  QLGSYLQE---KQKA-YSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQ 856
             L    +E   K KA ++EY ++   + +R  +L  ++++ +     I  +N+    +N 
Sbjct: 2296 NLKKSKEEEIEKMKAMFNEYKVKV--MQDRTEILSQNEQLKQNY---ISLQNELASSRNN 2350

Query: 857  ILLEENQNLQISLSDMQQHYNALVEKANRT-DLAESESTKYQTQLRDLESNLKRITHEHQ 915
              L E  +LQ  ++D+Q   + +  KAN      + +  + QT+  +L++N  ++ +E Q
Sbjct: 2351 --LSEINSLQSKVNDLQNENSNIKSKANSMLSSMQQKINELQTENINLKNNQSQL-NELQ 2407

Query: 916  TLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLN 975
                  + ++ +LE E  T+       ++ LNE    N     +  + L    N ++   
Sbjct: 2408 NSNNSLQTKLNELEKENETKNSEISSLQQKLNELQNDNTTIKNKANSILNSLNNQLKESQ 2467

Query: 976  MNVEELNKMN--LELIDKHVQKQQTQSPDYTEQYINEINKLNAL---LKQKDEEIIALNQ 1030
              + EL   N  ++ ++  +   QT++     Q    IN LN+    L+ + +EI  L  
Sbjct: 2468 TKLNELQNENTSIKTLETQIHSLQTENETIKSQSQETINSLNSRISELQNQIQEISQLQS 2527

Query: 1031 KINNAQVSYMSM-------VSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQH-NEELQ 1082
            ++N+ +    S+        + Y SK+++   + + +    +++S+  L   Q+ N+ L+
Sbjct: 2528 ELNDLKTENQSLHEKISELTNSYNSKISELQIENQEILSSKEQISQSKLSELQNENQSLK 2587

Query: 1083 ILVREQDDQIKEL--KETKLTFEMNIPKTEGMI-ISSTIEPMSDDANNVDXXXXXXXXXX 1139
            + + E++++ ++L    ++L  ++++ K +    IS     +++    +D          
Sbjct: 2588 LQISEKEEENEKLMNSNSELMNQIDLVKEDTKKEISHLQATINEKQTKIDGLNSQISQNE 2647

Query: 1140 XXL--KVQEEEEFIQERS----VLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQ 1193
                 K++  +  I E      +L+++ + L ++L+       ++ET N++        +
Sbjct: 2648 EERIGKLESLQSTIDEDKSQIEILEQKVSDLESKLENLQKHYSEIETKNSQYENFISKAR 2707

Query: 1194 EQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKT 1253
               N+ K+K+ QL TEN++L   V    ++ISS   Q    I+++ +++    E   Q  
Sbjct: 2708 VAFNENKAKISQLETENNSLKEKVVNYENAISSNDSQLKNFISQMKEENSKLEEEKSQLI 2767

Query: 1254 EHELRVQLSAFESKYEQLLDSVQSSTQEETN-KIVTMEQVTSLQNKLQDKEEHLRNLQEK 1312
            +   R+     E + +Q  + +    ++ T     T E+ T L  +  + EE ++ L+++
Sbjct: 2768 KENQRI--PQLEEENKQFANQLSKFNEKLTQIDRETEEEKTKLLTEKSNLEEEIKQLKQQ 2825

Query: 1313 YADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINE 1372
              ++ N+   L  +  + K                   D   + +   +++EQ I     
Sbjct: 2826 NEEINNEKVQLEEQFSNAKSKLAEEINQIKKPNEEINNDQSNKEEEKSKLREQ-INEFLN 2884

Query: 1373 ENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQ------KTHEYTIT 1426
            E   L++               +N+ + +  ++  +++L +++  Q         E    
Sbjct: 2885 ERTHLQEQIHQISNEKSQLQEELNEVKKQNEKINEEIQLLNNDKSQLQEDKSALEEVLKQ 2944

Query: 1427 LTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERV- 1485
            + Q+ND+  +  +    YEK+I DL   K SEL    +   E  +    +  ES IE++ 
Sbjct: 2945 MEQQNDQ-SSTEEMKSNYEKQINDL-QSKVSELENKLISQTEEKSQIANL--ESVIEKLR 3000

Query: 1486 ---KLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQ------EIEIVTL 1536
               K IEE  +K  + V   +  AE N   E+++ +       L+ Q        +I  L
Sbjct: 3001 NENKNIEEEKLKFEKQVKDLQTNAETNDQREDKITELKLRNAELQQQMKDYQNNSQINLL 3060

Query: 1537 NDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKEL 1580
             ++I +LQ+ + A   K ++ ++  S TK   +++    +N+++
Sbjct: 3061 QNQIKDLQSQISAQKQKYEEQIN--SQTKNEEEDEGIEVVNRDI 3102



 Score =  186 bits (454), Expect = 3e-45
 Identities = 288/1479 (19%), Positives = 639/1479 (43%), Gaps = 148/1479 (10%)

Query: 147  LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXX 206
            +S  I EKD  +S    K K     I  LQEK+ EK++ I +KN+A T            
Sbjct: 880  MSQAISEKDEEIS----KSK---NGISSLQEKLAEKEKEINSKNEANTAEKEENSKLISQ 932

Query: 207  XXXXXEDTKQQMTKMQENFIAME---AEWKDEKQRLLKDIESKDVRISSLEEANKLL--E 261
                  +  + + ++++     +   ++++ +   L+++I  K++ I+  E     L  +
Sbjct: 933  RDEEISNLNKSIDELRKEISTKDETISQFESKINELIEEISKKELTINEKETKIAELNEQ 992

Query: 262  AARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEK-TEIEEKGSLEIAN 320
              + E  +   K A+++ +               +   +E + + K TEI +K       
Sbjct: 993  ITQKENEINGLKEAEKVMETKISEIESQLTEKEKSINELEETVQNKETEINQKNEELSER 1052

Query: 321  MTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTAS 380
             T++ +  E++   + +I+Q N+E+ +  + +   ++ +S+       L  +     T  
Sbjct: 1053 ETKINELNEIISQKDSEIQQKNEEISSNNSKIDELNQQISNKENSLQELTDKVHSLET-- 1110

Query: 381  KMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXX 440
              K+   +   E L +   +K  +N   KL+  IQ+   ++ DK+  + E +        
Sbjct: 1111 --KNSEQETQIEELTKLVSEKEEENN--KLQETIQTKETEIKDKQSKVDEMNQEISDKDK 1166

Query: 441  XXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVK- 499
                    + +L+ E++          +    E ++ I   +E     LN ++ + N + 
Sbjct: 1167 SIEEITERVNKLEEENKTKNS-----QIDEMKEQISSITTNEETAISTLNTQLNNKNNEI 1221

Query: 500  DLI-EKLKSAEEQITQLNDEIDAANKNMIKVKSNH----KLKLKQMQKTI-----DNFSK 549
            DL+ ++L+S E +I QLN+EI   N N ++ K       +LK+ ++   I     +   K
Sbjct: 1222 DLLHQQLQSKETEIKQLNEEISERN-NALQTKETEIKEKELKINELNDIISKKEEEKAEK 1280

Query: 550  VSDSNKEIVRLTEE----LHHLSQKVAELEEEK-----GNLQLHLVDYDSGRMIESDVYK 600
             S  N+ I +L  E    ++ LS+K+ +LEE+       N  +   +    + I+   ++
Sbjct: 1281 ESLLNENINKLNTERESQINELSEKLLKLEEQLKQETLSNEDMKQTNTSLSQKIDEMAFQ 1340

Query: 601  KMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSD------Q 654
               +   L E   + I++L SQ  D  + ++ LQ++  E   +  + S++ +D      Q
Sbjct: 1341 LSDKTSQLQELN-QQITVLSSQISDKDKTVNDLQEEIKEKSVQNEENSRIINDLKEFIKQ 1399

Query: 655  VCSEIKSVHLEEQIDALSASK----KELALVIENLKLDKEQLYGTIKDLENDKEDIMNKL 710
               +IKS   +E+I ++   K     E+   +E  + +  QL+G I +L+N      ++ 
Sbjct: 1400 YDEDIKSK--DEKIKSIEQEKDAKINEIKAELETKETENSQLFGNISELQNMLSSRDSEY 1457

Query: 711  QNYIQENMDLTDKLEKMSA---EK---ISELLAKINHEEQSKIQTQFGIDAKIQERDLYI 764
            +    +N  L  ++E + +   EK    + +L+K + E  +  +    +  K +E    +
Sbjct: 1458 ETVCSDNNKLKQEIEALKSSLSEKENDFASILSKYDEEVSNHNKEVEELTKKDEENKQQV 1517

Query: 765  ENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELV 824
            +  E+E+S  K  I  L+ S+   ++      +  D    ++QE Q  + E   Q+ E +
Sbjct: 1518 DEKENEISNLKKEIENLKSSLNEKDNEISQNSQAIDDSSKHVQELQHQFDEDLKQKQEEI 1577

Query: 825  N-RLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKA 883
            + +   L +  +V+E++  EI      LQ+K++++ ++ + +    S +Q+    +    
Sbjct: 1578 SAKDEELSNLKKVLEEEKSEI---TSSLQEKDELIKQKEEEISNLNSVIQEKEKVIASLQ 1634

Query: 884  NRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDK 943
             + +   +E    + ++  L    K+   E  +L  +    I + E E + +++S+I DK
Sbjct: 1635 GKVNDENNEVNAKEAEIVSLNEIQKKKEEEISSLQEKLNSTIAEKEKEIS-ELQSSINDK 1693

Query: 944  KVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVE--ELNKMNLELIDKHVQKQQTQSP 1001
                   +K I       + LQE K NIEN ++N +  E++ +N +L  K  +    +S 
Sbjct: 1694 -------DKEI-------SSLQE-KVNIENNDVNTKETEISSLNDQLKQKDEEINNLKS- 1737

Query: 1002 DYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENME 1061
            +  E++  E++KL +L+ + ++ I++L +K+N+ +++  + +   E +++     ++  E
Sbjct: 1738 EIKEKF-EELSKLQSLVNENEQVIVSLQEKVNSDEINKENELKMKEEEISNLNGSIQEKE 1796

Query: 1062 EEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPM 1121
            +E+  + +   +S          + ++D++I  LK+     +  I  +    +   I  +
Sbjct: 1797 KEISLLKENFNNS----------LAQKDEEISNLKKVLEEEKSGITSS----LQEQISKL 1842

Query: 1122 SDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETL 1181
              +    D            L  ++ E   Q+   +   ++KLN  ++    K    E  
Sbjct: 1843 QSEIKERDEIQKKKEEEIQTLSNEKLELLKQKEEEINVLNSKLNESVELLKQKEGDNEN- 1901

Query: 1182 NTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQ 1241
            N +++      +++I++L+S++  L  E    LS   E    ++  + +R  EI+ +   
Sbjct: 1902 NDKISEIRQQKEKEISELQSEINSLKNE----LSANKEEMEKLNETIKERDEEISSI--- 1954

Query: 1242 HLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQD 1301
               +++AD  K+E           +    +L  ++     +T + +   +V S + ++ D
Sbjct: 1955 ---KQKADDDKSE----------VNSISNILSDIKQKLSNQTQESIKEGRVFSKEREVPD 2001

Query: 1302 KEEHLRNL-----QEKYADVINQIEILRSEIEDEK------VAFXXXXXXXXXXXXXXXX 1350
            +E ++  L     + K ++V+   E++    EDE        +                 
Sbjct: 2002 EETNISQLDYSPIKSKPSEVVKSREVIELVDEDEGNETNDIRSTVEYLSETIDEMQANIE 2061

Query: 1351 DLRTENQSYKQMQEQSILNINEE-NAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQL 1409
            +L+ EN + K  ++QS++  N++    L  +              +ND    +  LT +L
Sbjct: 2062 ELKKEN-AKKSQEKQSLIYQNQQLRILLDSAEIEMNKKSQGMMTMMNDKNGLIENLTKEL 2120

Query: 1410 ELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHEN 1469
            +   S++     +  +   Q+   F++  Q++    +R+  L  +K SE   +R + +  
Sbjct: 2121 QTTRSQL-NDIKQQAVYQMQQQKSFDD--QEI----QRLNGLISQKLSENEQMRQQFNLQ 2173

Query: 1470 ANHY-ETMQKESE-IERVKLIEELNVKITESVSLNKQVAELNKALEEEVA-KTNEMQTAL 1526
            A+   +T+Q++ E I ++K     N  + E ++ N  +  L K  EE+++ K NE+    
Sbjct: 2174 ADAMNKTIQEKDEMINQIK--TRANKLLNEKLNENSNLQNLQKENEEKLSQKENELNQIK 2231

Query: 1527 ENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTK 1565
                  I     +I+ LQN   A  +K+++      + K
Sbjct: 2232 SQLNTVIQNAQSQISALQNEKIAIENKMKQQEDLIQNMK 2270



 Score =  163 bits (395), Expect = 5e-38
 Identities = 228/1155 (19%), Positives = 534/1155 (46%), Gaps = 105/1155 (9%)

Query: 152  KEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXX 211
            +++ N  + ++  ++ +  TI ++Q  I E    ++ +N   +                 
Sbjct: 2033 EDEGNETNDIRSTVEYLSETIDEMQANIEE----LKKENAKKSQEKQSLIYQNQQLRILL 2088

Query: 212  EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271
            +  + +M K  +  + M     ++K  L++++ +K+++ ++  + N + + A +++  + 
Sbjct: 2089 DSAEIEMNKKSQGMMTM----MNDKNGLIENL-TKELQ-TTRSQLNDIKQQAVYQMQQQK 2142

Query: 272  SKLAQELEQXXXXXXXXXXXXXXLAKQ-SIEPSCEEKTEIEEKGSLEIANMTELTKKIEL 330
            S   QE+++              + +Q +++     KT I+EK  +     T   K +  
Sbjct: 2143 SFDDQEIQRLNGLISQKLSENEQMRQQFNLQADAMNKT-IQEKDEMINQIKTRANKLLNE 2201

Query: 331  LEHLNCQIRQTNKELENKLATMGTESKAVSSPS----KKGSPLISRKSGRNTA--SKMKS 384
              + N  ++   KE E KL+    E   + S      +     IS       A  +KMK 
Sbjct: 2202 KLNENSNLQNLQKENEEKLSQKENELNQIKSQLNTVIQNAQSQISALQNEKIAIENKMKQ 2261

Query: 385  PWSQLSSETL-NQDTDKKIN--KNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXX 441
                + +  L N+ +++ ++  + E +KLE +  +L K    +E +   K          
Sbjct: 2262 QEDLIQNMKLANESSEQSLSLLEGENSKLEQICANLKKS--KEEEIEKMKAMFNEYKVKV 2319

Query: 442  XXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDL 501
               +  +++Q +   Q ++   +   + ++  +++EI  +Q ++    N+   + N+K  
Sbjct: 2320 MQDRTEILSQNEQLKQNYISLQN--ELASSRNNLSEINSLQSKVNDLQNE---NSNIKSK 2374

Query: 502  IEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNF-SKVSDSNKEIVRL 560
               + S+ +Q  ++N E+   N N+     N++ +L ++Q + ++  +K+++  KE    
Sbjct: 2375 ANSMLSSMQQ--KIN-ELQTENINL----KNNQSQLNELQNSNNSLQTKLNELEKENETK 2427

Query: 561  TEELHHLSQKVAELEEEKGNLQLH---LVDYDSGRMIESDVYKKMIEMENLA----ETRL 613
              E+  L QK+ EL+ +   ++     +++  + ++ ES      ++ EN +    ET++
Sbjct: 2428 NSEISSLQQKLNELQNDNTTIKNKANSILNSLNNQLKESQTKLNELQNENTSIKTLETQI 2487

Query: 614  KAISLL-ESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALS 672
             ++    E+ K    + ++ L  +  E+++++ +ISQLQS+    + ++  L E+I  L+
Sbjct: 2488 HSLQTENETIKSQSQETINSLNSRISELQNQIQEISQLQSELNDLKTENQSLHEKISELT 2547

Query: 673  AS--KKELALVIENLKL--DKEQL-YGTIKDLEND----------KEDIMNKLQNYIQEN 717
             S   K   L IEN ++   KEQ+    + +L+N+          KE+   KL N   E 
Sbjct: 2548 NSYNSKISELQIENQEILSSKEQISQSKLSELQNENQSLKLQISEKEEENEKLMNSNSEL 2607

Query: 718  MDLTDKLEKMSAEKISELLAKINHEEQSKIQ-TQFGIDAKIQERDLYIENIESELSKYKS 776
            M+  D +++ + ++IS L A IN E+Q+KI      I    +ER   +E+++S + + KS
Sbjct: 2608 MNQIDLVKEDTKKEISHLQATIN-EKQTKIDGLNSQISQNEEERIGKLESLQSTIDEDKS 2666

Query: 777  RICRLEESIAVME------DRRYS-LERKADQLGSYLQEKQKAYSEYTIQ---------- 819
            +I  LE+ ++ +E       + YS +E K  Q  +++ + + A++E   +          
Sbjct: 2667 QIEILEQKVSDLESKLENLQKHYSEIETKNSQYENFISKARVAFNENKAKISQLETENNS 2726

Query: 820  -EDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNA 878
             ++++VN    +  +D  ++  + +++ EN +L+++   L++ENQ +     + +Q  N 
Sbjct: 2727 LKEKVVNYENAISSNDSQLKNFISQMKEENSKLEEEKSQLIKENQRIPQLEEENKQFANQ 2786

Query: 879  LV---EKANRTDL-AESESTKYQTQLRDLESNLKRITHEHQTL---IVQKKKEIEDLEIE 931
            L    EK  + D   E E TK  T+  +LE  +K++  +++ +    VQ +++  + + +
Sbjct: 2787 LSKFNEKLTQIDRETEEEKTKLLTEKSNLEEEIKQLKQQNEEINNEKVQLEEQFSNAKSK 2846

Query: 932  FNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDK 991
               +I    +  + +N       E  ++L  Q+ E+ N   +L   + +++    +L ++
Sbjct: 2847 LAEEINQIKKPNEEINNDQSNKEEEKSKLREQINEFLNERTHLQEQIHQISNEKSQLQEE 2906

Query: 992  --HVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESK 1049
               V+KQ  +  +  +   N+ ++L       +E +  + Q+  N Q S   M S+YE +
Sbjct: 2907 LNEVKKQNEKINEEIQLLNNDKSQLQEDKSALEEVLKQMEQQ--NDQSSTEEMKSNYEKQ 2964

Query: 1050 LAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKT 1109
            +    +K+  +E ++  +S+   + K     L+ ++ +  ++ K ++E KL FE  +   
Sbjct: 2965 INDLQSKVSELENKL--ISQ--TEEKSQIANLESVIEKLRNENKNIEEEKLKFEKQVKDL 3020

Query: 1110 EGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQ 1169
            +    + T +   D    +              +   +   +Q +  +++  ++++ + Q
Sbjct: 3021 Q--TNAETNDQREDKITELKLRNAELQQQMKDYQNNSQINLLQNQ--IKDLQSQISAQKQ 3076

Query: 1170 ECYTKIIQLETLNTEL-TGHDVVNQE-QINQ-LKSKLEQLNTENDNLLSTVAELRSSISS 1226
            + Y + I  +T N E   G +VVN++  +++  K   ++L  EN+ L   +++L + ++S
Sbjct: 3077 K-YEEQINSQTKNEEEDEGIEVVNRDINLDEGEKDDFQKLKEENEQLKKKISDLETKLNS 3135

Query: 1227 AVDQRGF---EIAEL 1238
             V++      +IAEL
Sbjct: 3136 YVNENAILQQKIAEL 3150



 Score =  156 bits (379), Expect = 4e-36
 Identities = 178/858 (20%), Positives = 370/858 (43%), Gaps = 56/858 (6%)

Query: 764  IENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDEL 823
            I + +  + +   R+ +LEE     + +   ++   +Q+ S    ++ A S    Q +  
Sbjct: 5    ISDKDKSIEEITERVNKLEEE---NKTKNSQIDEMKEQISSITTNEETAISTLNTQLNNK 61

Query: 824  VNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKA 883
             N + +L  H ++  K+  EI    + + ++ +   E  + L+ +  + ++  + +  K 
Sbjct: 62   NNEIDLL--HQQLQSKET-EISKLTENVSEREKSFTELQEQLEKAKQEHEETISEIKLKL 118

Query: 884  NRTDLAESESTKYQTQLR-DLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRD 942
               D   +E     +Q+R +LE   K+ T   +TL  QK+  I ++    +   E     
Sbjct: 119  ESKDNEINELNSTLSQIRSELEQTNKQNTELTETLS-QKESNINEINDNLSKLREEISEK 177

Query: 943  KKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPD 1002
            +K +NEK  K  E   Q+  +    K   E +N N+EE NK     I++   +QQ +S  
Sbjct: 178  EKTINEKSSKIEELNQQISEKDNSLKEMTEKIN-NLEEENKQKNSRIEE--LQQQLESLR 234

Query: 1003 YTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEE 1062
              ++  N IN L   L QK+ +I  LN+ +   Q    +++S    ++ +  +K+  +EE
Sbjct: 235  NDDE--NRINNLYEELSQKESKINELNELMMQQQTGKETILSQLNEQIKEKDSKIGELEE 292

Query: 1063 EMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMI--ISSTIEP 1120
             + ++  ++   + +  EL   V E+D  + ++ E K   +  +     MI  ++  I+ 
Sbjct: 293  NVSKLESEISQKESNINELSSQVSEKDKMVNDISEEKNELQKQLSDQNSMIDELNEQIKE 352

Query: 1121 MSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLET 1180
            ++D+ +               L  ++E E     S L+E+ +KL TE      K+IQ   
Sbjct: 353  LTDNLSKSTTESTEKDSKNQELISEKETEI----SHLKEEISKL-TEQHGEKDKLIQ--E 405

Query: 1181 LNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWK 1240
            L  ++   D +N +Q +   S+L+ L ++ +  LS      +     ++++  +I EL  
Sbjct: 406  LTEQIQTQD-INLKQKDSNISELQVLVSQKETELSEKDNSINEFIHKLEEKDLQIKEL-N 463

Query: 1241 QHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQ 1300
            + L  +E+      +EL  Q+S  E+  +++ D V +  +   NK     ++     +L 
Sbjct: 464  EQLNNKESQI----NELNAQISDKENSLQEITDKVHTLEETVQNK---ETEINQKNEELS 516

Query: 1301 DKEEHLRNLQEKYADVINQIEILRSEI--EDEKVAFXXXXXXXXXXXXXXXXDLRTENQS 1358
            ++E  +  L E  +   ++I+    EI   + K+                  D     ++
Sbjct: 517  ERETKINELNEIISQKDSEIQQKNEEISSNNSKIDELNQQISNKENSLQELTDKVHSLET 576

Query: 1359 YKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQ 1418
                QE  I  + +  ++ ++ +             + D ++KV E+  ++  KD  I  
Sbjct: 577  KNSEQETQIDELTKLVSEKEEENNKLQETIQTKETEIKDKQSKVDEMNQEISDKDKSI-- 634

Query: 1419 KTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENAN-----HY 1473
               E T  + +  +E +    Q+ E +++I  +T  +E+ ++ L  +++   N     H 
Sbjct: 635  --EEITERVNKLEEENKTKNSQIDEMKEQISSITTNEETAISTLNTQLNNKNNEIDLLHQ 692

Query: 1474 ETMQKESEIERV---------KLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQT 1524
            +   KE+E E+          KL EE+  K T    LN+Q++  N+ + +   K   + T
Sbjct: 693  QLQSKETENEKAINELNDKLNKLYEEIANKNTNITELNEQISSKNQEIVDRDNKLQSLGT 752

Query: 1525 ALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDN---TMNKELL 1581
             L  +  EI   + +I    ++V    S+I +     +D    + E+L+N   T +  +L
Sbjct: 753  ELNQKNEEIKEKDSKIGEFNDLVSKKDSEINQLQEEIADI-SSKIEELNNEIATKDASIL 811

Query: 1582 DAVPR-AELDLAMYMLHQ 1598
            +   + AE DL +  L +
Sbjct: 812  ELNNKIAEKDLKIKSLDE 829



 Score =  114 bits (274), Expect = 2e-23
 Identities = 194/976 (19%), Positives = 415/976 (42%), Gaps = 73/976 (7%)

Query: 140  QLGDVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINE-KDQIIEAKNKATTXXXX 198
            QL ++ + +N+++ K   L+ L+ + +   + I  LQ+K+NE ++     KNKA +    
Sbjct: 2402 QLNELQNSNNSLQTK---LNELEKENETKNSEISSLQQKLNELQNDNTTIKNKANSILNS 2458

Query: 199  XXXXXXXXXXXXXE--DTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEA 256
                         E  +    +  ++    +++ E +  K +  + I S + RIS L+  
Sbjct: 2459 LNNQLKESQTKLNELQNENTSIKTLETQIHSLQTENETIKSQSQETINSLNSRISELQ-- 2516

Query: 257  NKLLEAARFEISLEHSKLA-QELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGS 315
            N++ E ++ +  L   K   Q L +                +   +     K +I +   
Sbjct: 2517 NQIQEISQLQSELNDLKTENQSLHEKISELTNSYNSKISELQIENQEILSSKEQISQSKL 2576

Query: 316  LEIANMTELTK-KIELLEHLNCQIRQTNKELENKLATMGTESKA-VSSPSKKGSPLISRK 373
             E+ N  +  K +I   E  N ++  +N EL N++  +  ++K  +S      +   ++ 
Sbjct: 2577 SELQNENQSLKLQISEKEEENEKLMNSNSELMNQIDLVKEDTKKEISHLQATINEKQTKI 2636

Query: 374  SGRNT--ASKMKSPWSQLSSETLNQDTDK---KINKNEIAKLEMVIQSLNKDLVDKEYVI 428
             G N+  +   +    +L S     D DK   +I + +++ LE  +++L K   + E   
Sbjct: 2637 DGLNSQISQNEEERIGKLESLQSTIDEDKSQIEILEQKVSDLESKLENLQKHYSEIETKN 2696

Query: 429  SEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQE 488
            S+ +                I+QL+ E+       SL     N E  N I+    QLK  
Sbjct: 2697 SQYENFISKARVAFNENKAKISQLETENN------SLKEKVVNYE--NAISSNDSQLKNF 2748

Query: 489  LNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDN-- 546
            ++ ++K+ N K  +E+ KS   +  Q   +++  NK      S    KL Q+ +  +   
Sbjct: 2749 IS-QMKEENSK--LEEEKSQLIKENQRIPQLEEENKQFANQLSKFNEKLTQIDRETEEEK 2805

Query: 547  ---FSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVD-YDSGRMIESDVYKKM 602
                ++ S+  +EI +L ++   ++ +  +LEE+  N +  L +  +  +    ++    
Sbjct: 2806 TKLLTEKSNLEEEIKQLKQQNEEINNEKVQLEEQFSNAKSKLAEEINQIKKPNEEINNDQ 2865

Query: 603  IEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSV 662
               E       + I+   +++  L +++H +  +  +++++L ++ + Q++++  EI+ +
Sbjct: 2866 SNKEEEKSKLREQINEFLNERTHLQEQIHQISNEKSQLQEELNEVKK-QNEKINEEIQLL 2924

Query: 663  HLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQE--NMDL 720
            + ++    L   K  L  V++ ++   +Q   + ++++++ E  +N LQ+ + E  N  +
Sbjct: 2925 NNDKS--QLQEDKSALEEVLKQMEQQNDQ--SSTEEMKSNYEKQINDLQSKVSELENKLI 2980

Query: 721  TDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICR 780
            +   EK     +  ++ K+ +E ++  + +   + ++++     E  +    K      R
Sbjct: 2981 SQTEEKSQIANLESVIEKLRNENKNIEEEKLKFEKQVKDLQTNAETNDQREDKITELKLR 3040

Query: 781  LEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQ 840
              E    M+D  Y    + + L + +++ Q   S    + +E +N      + D  +E  
Sbjct: 3041 NAELQQQMKD--YQNNSQINLLQNQIKDLQSQISAQKQKYEEQINSQTKNEEEDEGIEVV 3098

Query: 841  LLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKAN--RTDLAE-----SES 893
              +I  +  E +   Q L EEN+ L+  +SD++   N+ V +    +  +AE       S
Sbjct: 3099 NRDINLDEGE-KDDFQKLKEENEQLKKKISDLETKLNSYVNENAILQQKIAELGGDIDVS 3157

Query: 894  TKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKN 953
              Y +    + + L+ +      L  ++ K IEDLE     +I+S      V N  YE  
Sbjct: 3158 IDYGSDKDAIIAKLRILLQRALRLDKKRVKTIEDLE----EKIKSF--GVSVHNSSYE-- 3209

Query: 954  IEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINK 1013
                 QLE Q++E K  IEN N   ++L + N E + K VQK  T      E+    I  
Sbjct: 3210 ----AQLEEQIKELKQKIEN-NEASDDLIQKN-ESLKKMVQKSNTLYGQLMEENQQLIKT 3263

Query: 1014 LNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLD 1073
            L +   + D    +  +K    Q   + +VS  E+++ +  T  +    +   V    +D
Sbjct: 3264 LKSYKAKSDSG--SSPKKPTRVQ---LKIVSTNETEIEEIVTPSQTNRNDQSNV----MD 3314

Query: 1074 SKQHNEELQILVREQD 1089
                   LQ  ++++D
Sbjct: 3315 RYLRRSLLQFFLQDED 3330


>UniRef50_A2DGN0 Cluster: Viral A-type inclusion protein, putative;
            n=1; Trichomonas vaginalis G3|Rep: Viral A-type inclusion
            protein, putative - Trichomonas vaginalis G3
          Length = 4263

 Score =  232 bits (567), Expect = 7e-59
 Identities = 316/1559 (20%), Positives = 667/1559 (42%), Gaps = 112/1559 (7%)

Query: 92   ESLANTLKQKEILMEKIKQYKELSKRSSTTI--VRXXXXXXXXXXXXXXXQLGDVTHLSN 149
            ES     K+   L  +I+ Y++       T+  +R               +  D+     
Sbjct: 1259 ESTEALQKKSRELYRQIRDYEQRLSSLGLTVEQIREMEMTIKNQANIIKAKDDDLKQTKE 1318

Query: 150  TIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXX 209
             ++ ++  +     +   +   I  L+++I+E + ++E K+K                  
Sbjct: 1319 ILEYREEQIEKFIAESVSIRDAIETLKQRISELEMLLEKKDKENNDKIAEIQEENRQTL- 1377

Query: 210  XXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISL 269
              E   +Q+ + +E+   +E   +  +Q    +I  KD +I  +    K LE    E+  
Sbjct: 1378 --EQLAKQLQEAEEDINVLEGNCQVYEQ----EIAEKDKQIEQMTNDIKSLE----EVIN 1427

Query: 270  EHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIE 329
            E S     L+Q                 ++ E   + +T+IE+K +    N  E+ +  +
Sbjct: 1428 EQSNTIDSLKQDVATKEEEIKQLKQTVSENEEVIKQLQTDIEQKDAEIQKNKEEIEQHKQ 1487

Query: 330  LLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQL 389
             +   +  I+Q   E+E    T+  ++  +          IS +    T  ++++   Q 
Sbjct: 1488 TISQRDETIKQLQSEIEQHKQTIADKNNEIEQLKNT----ISERE--ETIKQLQNEIEQH 1541

Query: 390  SSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLI 449
                  +D + + NK EI + +  I + N ++   +  ISE+D            +D  I
Sbjct: 1542 KQTMAERDAEIQKNKEEIEQQKQTISNNNNEIEQLKKTISERDAEIEQLKKTIAERDESI 1601

Query: 450  AQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAE 509
             QLQ E +QH +      +     ++ ++ +  +Q  Q + +  K+  +K L  +++  +
Sbjct: 1602 KQLQNEIEQHKQ-----TISQRDAEIEQLKQTVQQRDQTIAE--KEDLIKQLQSEIEQHK 1654

Query: 510  EQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSK-VSDSNKEIVRLTEELHHLS 568
            + I+  N+EI+   K  +  +      +KQ+Q  I+   + +++ + EI +  EE+    
Sbjct: 1655 QTISDKNNEIEQL-KQTVNARDE---AIKQLQSEIEQHKQTIAERDAEIQKNKEEIEQQK 1710

Query: 569  QKVAELEEEKGNLQLHLVDYD---SGRMIESDVYKKMIEM--ENLAETR--LKAI-SLLE 620
            Q +++ +E    LQ  +  +    S R  E +  K+ ++   + +AE    +K + S +E
Sbjct: 1711 QTISQRDETIKQLQNEIEQHKQTISQRDAEIEQLKQTVQQSDQTIAEKEDLIKQLQSEIE 1770

Query: 621  SQKFDLVQELHILQQKYDEVEDKLADISQLQSD--QVCSEIKS-----VHLEEQIDALSA 673
              K  + +    +Q+  +E+E +   ISQ      Q+ SEI+         E++I+    
Sbjct: 1771 QHKQTIAERDAEIQKNKEEIEQQKQTISQRDESIKQMQSEIEQNKQTIADREKEIEQHKQ 1830

Query: 674  SKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKIS 733
            +  E    I+ L+ + EQ   TI   E D E   NK +  IQ+  +  + L     EK  
Sbjct: 1831 TIAERDNSIKQLQEEIEQHKQTI--AERDAEIQKNKEE--IQQKNEAINALTNEGEEKRL 1886

Query: 734  ELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRY 793
            ++L ++    ++ I     ++  + + +L  EN  S + +    I  L + I  +E +  
Sbjct: 1887 KIL-ELEANNENLINKVKELNDSVSDLNLSTENQNSVVKQMTDEIKDLNKQIHELEVKSE 1945

Query: 794  SLERKADQLGSYLQE--KQKAYSEYTIQE-DELVNRLAVLMDHDRVVEKQLLEIEHENKE 850
            + +++ ++    +Q     KA +E  I++  E V  L    + +    K L E      E
Sbjct: 1946 NQQKQIEEKDKEIQSLTNTKAQNEELIKKLQEEVENLTNTKNQNEETIKNLQEQVQSLTE 2005

Query: 851  LQKKNQILLEENQNLQISLSDMQQHYNALVEKANR--TDLAESESTKYQTQLRDLESNLK 908
             + +N+ L+++ Q    SL++ +      ++        L E+++T  +T ++ L+  ++
Sbjct: 2006 TKNQNEDLIKKQQEQIQSLTNTKNENEETIKNLQEQVQSLTETKATNEET-IKKLQGEVQ 2064

Query: 909  RITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYK 968
             +T    T   Q KK+ E+++   NT+ E+    KK L E+ +      TQ E Q+++ +
Sbjct: 2065 SLTETKATNEEQIKKQQEEIQSLSNTKNENEELIKK-LQEEIQNLTNTKTQNEEQIKKLQ 2123

Query: 969  NNIENL-NMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQ---KDEE 1024
              I+NL   N E+ +K+N    +  +    + S + T ++IN  N++N L KQ   KD  
Sbjct: 2124 EEIQNLQKQNAEKDDKIN--EFNAKLSTLSSSSDELTTKFINAQNEINQLTKQNNEKDNL 2181

Query: 1025 IIALNQKINNAQVSYMSMVSDYESKLAQFTTKLE-----------NMEEEMQRVSKQLLD 1073
            I  LNQKI++ + +  S + + +S+L Q  T LE           N+EEE Q++  +  +
Sbjct: 2182 ISQLNQKISDLE-NAKSQLENEKSQLIQEKTNLEQEKAQLLEQKKNLEEEKQKLETEKTN 2240

Query: 1074 SKQHNEELQILVREQDDQIKELKETKLTFEMNIPK--TEGMIISSTIEPMSDDANNVDXX 1131
             +Q   +L       + +  +L E K   E    K   E   +      + ++  N++  
Sbjct: 2241 LEQEKAKLIEEKTNLEQEKAKLIEEKTNLEQEKAKLIEEKTNLEQEKAKLIEEKTNLEQE 2300

Query: 1132 XXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKL---NTELQECYTKIIQLETLNTELTGH 1188
                      L+ QE+ + I+E++ L+++ AKL    T L++   K+I+ +T   +    
Sbjct: 2301 KAKLIEEKTNLE-QEKAKPIEEKTNLEQEKAKLIEEKTNLEQEKAKLIEEKTNLEQEKAK 2359

Query: 1189 DVVNQEQINQLKSKL--EQLNTEND--NLLSTVAELRSSISSAVDQRGFEIAELWKQHLA 1244
             +  +  + Q K+KL  E+ N E +   L+     L    +  ++++     E  K  L 
Sbjct: 2360 LIEEKTNLEQEKAKLIEEKTNLEQEKAKLIEEKTNLEQEKAKLIEEK--TNLEQEKAKLI 2417

Query: 1245 QREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEE 1304
            + + + ++ + +L  + +  E +  QLLD  + + +EE  ++ T E+   +++K   ++E
Sbjct: 2418 EEKTNLEQEKAKLIEEKTNLEQEKSQLLDQ-KKNLEEEKQRLET-EKAKLIEDKTNLEQE 2475

Query: 1305 HLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQE 1364
              + L++K       +E  ++++E+EK                    +  + +    + E
Sbjct: 2476 KAQLLEQK-----KNLEEEKAKLEEEKAQAQKTIEEKDQEIEDLTSQINVKTKDL-SLLE 2529

Query: 1365 QSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYT 1424
                N++  NA                   +ND + ++ ++T   +    E+  K+ +  
Sbjct: 2530 SDFNNMSFTNADQSTMISNYEKELSDKNKEINDLQNQLKQMTQNRD----ELQSKSDKLN 2585

Query: 1425 ITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIER 1484
              + ++ +  +N+   L +  K  EDL  +       L  ++ +     E + KE    +
Sbjct: 2586 EEIEEKKN-IQNLESSLEQKNKENEDLKQQLNKTQGELSAQLQQKTQELENLTKEFNDLK 2644

Query: 1485 VKLIEELNVKITESVSLNKQVAELNKALEEEVA-KTNEMQTALENQEIEIVTLNDEITNL 1543
             K  + +     E  +L K VAE +K + + +  + NE++  L ++E E  +L + I+  
Sbjct: 2645 QKSEQTIAQNNEEIANLKKNVAERDKKISQLLENEVNELKKKLSDKENENTSLKNTISER 2704

Query: 1544 QNMVRASSSKIQKHVSFASDTKQGRDEQLDN--TMNKELLDAVPRAELDLAMYMLHQRD 1600
            +N +    + ++K+VS     K+    QL N  TM +  L+ +   E+  A  ++ Q+D
Sbjct: 2705 ENEI----NNLKKNVS----DKENEINQLKNNLTMRETELNKMKDEEVKNAKQIIAQKD 2755



 Score =  223 bits (544), Expect = 4e-56
 Identities = 300/1539 (19%), Positives = 651/1539 (42%), Gaps = 108/1539 (7%)

Query: 106  EKIKQYKE-LSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNALSVLQVK 164
            E+I+Q K+ +S+R  T  ++               +  ++  L  T+++ D  ++  +  
Sbjct: 1704 EEIEQQKQTISQRDET--IKQLQNEIEQHKQTISQRDAEIEQLKQTVQQSDQTIAEKEDL 1761

Query: 165  MKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQEN 224
            +K +++ I   ++ I E+D  I+ KNK                    E  KQ  +++++N
Sbjct: 1762 IKQLQSEIEQHKQTIAERDAEIQ-KNKEEIEQQKQTISQRD------ESIKQMQSEIEQN 1814

Query: 225  FIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXX 284
               + A+ + E ++  + I  +D  I  L+E  +  +    E   E  K  +E++Q    
Sbjct: 1815 KQTI-ADREKEIEQHKQTIAERDNSIKQLQEEIEQHKQTIAERDAEIQKNKEEIQQKNEA 1873

Query: 285  XXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLE--IANMTELTK-KIELLEHLNCQIRQT 341
                         + +E     +  I +   L   ++++   T+ +  +++ +  +I+  
Sbjct: 1874 INALTNEGEEKRLKILELEANNENLINKVKELNDSVSDLNLSTENQNSVVKQMTDEIKDL 1933

Query: 342  NKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKK 401
            NK++         + K +    K+   L + K+      K      +L  E  N    K 
Sbjct: 1934 NKQIHELEVKSENQQKQIEEKDKEIQSLTNTKAQNEELIK------KLQEEVENLTNTKN 1987

Query: 402  INKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHME 461
             N+  I  L+  +QSL +     E +I ++              +  I  LQ + Q   E
Sbjct: 1988 QNEETIKNLQEQVQSLTETKNQNEDLIKKQQEQIQSLTNTKNENEETIKNLQEQVQSLTE 2047

Query: 462  GPSLIHVGTNTEDVNEI-AKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEID 520
              +     TN E + ++  +VQ   + +  +E +    ++ I+ L + + +  +L  ++ 
Sbjct: 2048 TKA-----TNEETIKKLQGEVQSLTETKATNEEQIKKQQEEIQSLSNTKNENEELIKKLQ 2102

Query: 521  AANKNMIKVKSNHKLKLKQMQKTIDNFSKVS-DSNKEIVRLTEELHHLSQKVAELEEEKG 579
               +N+   K+ ++ ++K++Q+ I N  K + + + +I     +L  LS    EL  +  
Sbjct: 2103 EEIQNLTNTKTQNEEQIKKLQEEIQNLQKQNAEKDDKINEFNAKLSTLSSSSDELTTKFI 2162

Query: 580  NLQ-----LHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQE-LHIL 633
            N Q     L   + +   +I S + +K+ ++EN         S L  +K +L QE   +L
Sbjct: 2163 NAQNEINQLTKQNNEKDNLI-SQLNQKISDLENAKSQLENEKSQLIQEKTNLEQEKAQLL 2221

Query: 634  QQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLY 693
            +QK +  E+K     +L++++   E +   L E+   L   K +L     NL+ +K +L 
Sbjct: 2222 EQKKNLEEEK----QKLETEKTNLEQEKAKLIEEKTNLEQEKAKLIEEKTNLEQEKAKLI 2277

Query: 694  GTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGI 753
                +LE +K  ++ +  N  QE   L ++   +  EK   +  K N E++     +   
Sbjct: 2278 EEKTNLEQEKAKLIEEKTNLEQEKAKLIEEKTNLEQEKAKPIEEKTNLEQEKAKLIEEKT 2337

Query: 754  DAKIQERDLYIE--NIESELSKYKSRICRLEESIAVMEDRRYSLERKADQL----GSYLQ 807
            + + ++  L  E  N+E E +K       LE+  A + + + +LE++  +L     +  Q
Sbjct: 2338 NLEQEKAKLIEEKTNLEQEKAKLIEEKTNLEQEKAKLIEEKTNLEQEKAKLIEEKTNLEQ 2397

Query: 808  EKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQI 867
            EK K   E T  E E     A L++    +E++  ++  E   L+++   LL++ +NL+ 
Sbjct: 2398 EKAKLIEEKTNLEQEK----AKLIEEKTNLEQEKAKLIEEKTNLEQEKSQLLDQKKNLEE 2453

Query: 868  SLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIED 927
                ++     L+E     +  +++  + +  L + ++ L+    + Q  I +K +EIED
Sbjct: 2454 EKQRLETEKAKLIEDKTNLEQEKAQLLEQKKNLEEEKAKLEEEKAQAQKTIEEKDQEIED 2513

Query: 928  LEIEFNTQ------IESAIR-------DKKVLNEKYEKNI----EYVTQLEAQLQEYKNN 970
            L  + N +      +ES          D+  +   YEK +    + +  L+ QL++   N
Sbjct: 2514 LTSQINVKTKDLSLLESDFNNMSFTNADQSTMISNYEKELSDKNKEINDLQNQLKQMTQN 2573

Query: 971  IENLNMNVEELN-----KMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEI 1025
             + L    ++LN     K N++ ++  ++++  ++ D  +Q      +L+A L+QK +E+
Sbjct: 2574 RDELQSKSDKLNEEIEEKKNIQNLESSLEQKNKENEDLKQQLNKTQGELSAQLQQKTQEL 2633

Query: 1026 IALNQKINN-AQVSYMSM------VSDYESKLAQFTTKLEN-MEEEMQRVSKQLLDSKQH 1077
              L ++ N+  Q S  ++      +++ +  +A+   K+   +E E+  + K+L D +  
Sbjct: 2634 ENLTKEFNDLKQKSEQTIAQNNEEIANLKKNVAERDKKISQLLENEVNELKKKLSDKENE 2693

Query: 1078 NEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXX 1137
            N  L+  + E++++I  LK+     E  I +     + + +     + N +         
Sbjct: 2694 NTSLKNTISERENEINNLKKNVSDKENEINQ-----LKNNLTMRETELNKMKDEEVKNAK 2748

Query: 1138 XXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQIN 1197
                 K ++ EE   + +      +K N EL++   +I  L     ++   + + + +I 
Sbjct: 2749 QIIAQKDKDLEELNGKFNDTNNNLSKANDELKQLKEQIESLNKQIEQMKCSNNLKESEIK 2808

Query: 1198 QLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHEL 1257
            QL S L++        L  + +      S ++Q   E+ EL +Q L Q +   ++T+ +L
Sbjct: 2809 QLTSNLQKYK----QALKELNDQNKQKDSQINQLNNEMKEL-QQTLKQTQEQLKETQDQL 2863

Query: 1258 RVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVI 1317
            +       +K ++   S +    E   K    + +  LQN L+ K+  L + ++K     
Sbjct: 2864 KQTQETLATKEKEFAKSAEDLNNELKKK---QQAIDDLQNNLKQKDAELTDTKQKLEAKT 2920

Query: 1318 NQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLR-TENQSYKQMQEQSILNINEENAQ 1376
            N+   L+ + E+E  +                 +L  ++++S  Q +E   L +N   A+
Sbjct: 2921 NEFNDLKQKAENEIASLRKEIEQLKAKLANTSKELEASKSESDLQKKENDKLKVN--LAK 2978

Query: 1377 LKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFEN 1436
            + +              + ND   ++ E    LE++  ++       T     + +  E 
Sbjct: 2979 IAEMYKTLKSESENNSAKSNDKIKQMQEKIQNLEIQVEKMKLANENLTNENKLQKETIEM 3038

Query: 1437 VRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESE--IERVKLIEELNVK 1494
            + ++L+E  K +     E E+      L+  +       +QK ++   +  K   E++ K
Sbjct: 3039 LNKKLLESNKSLTASIKEYETLKRENNLQKDQITKLTSQVQKLTQDFTQLKKEKAEVDSK 3098

Query: 1495 ITESVSLNKQVAELNKALEEEVAKTNEMQTA----LENQEIEIVTLNDEITNLQNMVRAS 1550
            + E + L  Q  +  + L+ E  K NE+       LE +E  I + N+   +L N+    
Sbjct: 3099 LNELLDLLAQKDKEIERLKSENQKLNELYQQITKDLEEKEFLIQSQNNRCIDLLNLTEKK 3158

Query: 1551 SSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAEL 1589
            + +I        +T Q  ++ L+N++ K  ++   ++ L
Sbjct: 3159 NKEI--------ETLQISNDSLNNSLTKSQMELREKSTL 3189



 Score =  199 bits (486), Expect = 4e-49
 Identities = 310/1467 (21%), Positives = 621/1467 (42%), Gaps = 122/1467 (8%)

Query: 151  IKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNK--ATTXXXXXXXXXXXXXX 208
            + E    +S  + K+KIM   I     KI E +  IE KNK   +T              
Sbjct: 1216 LSEVPQQISYFENKVKIMNGMITQSNAKIKELESQIEKKNKQIESTEALQKKSRELYRQI 1275

Query: 209  XXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEIS 268
               E     +    E    ME   K++       I++KD  +   +E  +  E    +  
Sbjct: 1276 RDYEQRLSSLGLTVEQIREMEMTIKNQ----ANIIKAKDDDLKQTKEILEYREEQIEKFI 1331

Query: 269  LEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKI 328
             E   +   +E                 K++ +   E + E  +        + E  + I
Sbjct: 1332 AESVSIRDAIETLKQRISELEMLLEKKDKENNDKIAEIQEENRQTLEQLAKQLQEAEEDI 1391

Query: 329  ELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQ 388
             +LE  NCQ+       E ++A    + + +++  K    +I+ +S  NT   +K     
Sbjct: 1392 NVLEG-NCQV------YEQEIAEKDKQIEQMTNDIKSLEEVINEQS--NTIDSLK----- 1437

Query: 389  LSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTL 448
               +   ++ + K  K  +++ E VI+ L  D+  K+  I +              +D  
Sbjct: 1438 --QDVATKEEEIKQLKQTVSENEEVIKQLQTDIEQKDAEIQKNKEEIEQHKQTISQRDET 1495

Query: 449  IAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSA 508
            I QLQ E +QH +        T  +  NEI    EQLK  +++       ++ I++L++ 
Sbjct: 1496 IKQLQSEIEQHKQ--------TIADKNNEI----EQLKNTISER------EETIKQLQNE 1537

Query: 509  EEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTI-DNFSKVSDSNKEIVRLTEELHHL 567
             EQ  Q   E DA      +++ N K +++Q ++TI +N +++    K I     E+  L
Sbjct: 1538 IEQHKQTMAERDA------EIQKN-KEEIEQQKQTISNNNNEIEQLKKTISERDAEIEQL 1590

Query: 568  SQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLV 627
             + +AE +E    LQ  +  +      +  + ++  E+E L +T  +    + ++K DL+
Sbjct: 1591 KKTIAERDESIKQLQNEIEQH------KQTISQRDAEIEQLKQTVQQRDQTI-AEKEDLI 1643

Query: 628  QELHI-LQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLK 686
            ++L   ++Q    + DK  +I QL+      +     L+ +I+    +  E    I+  K
Sbjct: 1644 KQLQSEIEQHKQTISDKNNEIEQLKQTVNARDEAIKQLQSEIEQHKQTIAERDAEIQKNK 1703

Query: 687  LDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSK 746
             + EQ   TI   +   + + N+++ + Q       ++E++  + + +    I  +E   
Sbjct: 1704 EEIEQQKQTISQRDETIKQLQNEIEQHKQTISQRDAEIEQLK-QTVQQSDQTIAEKEDLI 1762

Query: 747  IQTQFGID---AKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLG 803
             Q Q  I+     I ERD  I+  + E+ + K  I + +ESI  M+     +E+    + 
Sbjct: 1763 KQLQSEIEQHKQTIAERDAEIQKNKEEIEQQKQTISQRDESIKQMQS---EIEQNKQTIA 1819

Query: 804  SYLQEKQKAYSEYTIQE-DELVNRL-AVLMDHDRVVEKQLLEIEHENKELQKKNQ---IL 858
               +EK+    + TI E D  + +L   +  H + + ++  EI+   +E+Q+KN+    L
Sbjct: 1820 D--REKEIEQHKQTIAERDNSIKQLQEEIEQHKQTIAERDAEIQKNKEEIQQKNEAINAL 1877

Query: 859  LEENQNLQISLSDMQQHYNALVEKANRTDLAESE---STKYQT----QLRDLESNLKRIT 911
              E +  ++ + +++ +   L+ K    + + S+   ST+ Q     Q+ D   +L +  
Sbjct: 1878 TNEGEEKRLKILELEANNENLINKVKELNDSVSDLNLSTENQNSVVKQMTDEIKDLNKQI 1937

Query: 912  HEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNI 971
            HE +     ++K+IE+ + E  +   +  ++++++ +K ++ +E +T  + Q +E   N+
Sbjct: 1938 HELEVKSENQQKQIEEKDKEIQSLTNTKAQNEELI-KKLQEEVENLTNTKNQNEETIKNL 1996

Query: 972  ENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQK 1031
            +    ++ E    N +LI K  Q++Q QS        N  N+    +K   E++ +L + 
Sbjct: 1997 QEQVQSLTETKNQNEDLIKK--QQEQIQS------LTNTKNENEETIKNLQEQVQSLTET 2048

Query: 1032 INNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQ 1091
                + +   +  + +S      T  E ++++ + + + L ++K  NEE   L+++  ++
Sbjct: 2049 KATNEETIKKLQGEVQSLTETKATNEEQIKKQQEEI-QSLSNTKNENEE---LIKKLQEE 2104

Query: 1092 IKELKETKLTFEMNIPKTEGMI--ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEE 1149
            I+ L  TK   E  I K +  I  +        D  N  +            L  +    
Sbjct: 2105 IQNLTNTKTQNEEQIKKLQEEIQNLQKQNAEKDDKINEFNAKLSTLSSSSDELTTKFINA 2164

Query: 1150 FIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTE 1209
               E + L +Q+ + +  + +   KI  LE   ++L        ++   L+ +  QL  +
Sbjct: 2165 -QNEINQLTKQNNEKDNLISQLNQKISDLENAKSQLENEKSQLIQEKTNLEQEKAQLLEQ 2223

Query: 1210 NDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADF--QKTEHEL-RVQLSAFES 1266
              NL     +L +  ++   ++   I E  K +L Q +A    +KT  E  + +L   ++
Sbjct: 2224 KKNLEEEKQKLETEKTNLEQEKAKLIEE--KTNLEQEKAKLIEEKTNLEQEKAKLIEEKT 2281

Query: 1267 KYEQ-LLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRS 1325
              EQ     ++  T  E  K   +E+ T+L+ +     E   NL+++ A +I +    ++
Sbjct: 2282 NLEQEKAKLIEEKTNLEQEKAKLIEEKTNLEQEKAKPIEEKTNLEQEKAKLIEE----KT 2337

Query: 1326 EIEDEKVAFXXXXXXXXXXXXXXXXD-LRTENQSYKQMQEQSILNINEENAQL---KKSS 1381
             +E EK                   +    E +  K ++E++  N+ +E A+L   K + 
Sbjct: 2338 NLEQEKAKLIEEKTNLEQEKAKLIEEKTNLEQEKAKLIEEKT--NLEQEKAKLIEEKTNL 2395

Query: 1382 XXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSE-IYQKTH---EYTITLTQRNDEFENV 1437
                         +   +AK++E    LE + ++ I +KT+   E +  L Q+ +  E  
Sbjct: 2396 EQEKAKLIEEKTNLEQEKAKLIEEKTNLEQEKAKLIEEKTNLEQEKSQLLDQKKNLEEEK 2455

Query: 1438 RQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITE 1497
            ++   E  K IED T   E E A L L+  +N    +   +E + +  K IEE + +I +
Sbjct: 2456 QRLETEKAKLIEDKT-NLEQEKAQL-LEQKKNLEEEKAKLEEEKAQAQKTIEEKDQEIED 2513

Query: 1498 SVS-LNKQVAELNKALEEE---VAKTN-EMQTALENQEIEIVTLNDEITNLQNMVRASSS 1552
              S +N +  +L+  LE +   ++ TN +  T + N E E+   N EI +LQN ++  + 
Sbjct: 2514 LTSQINVKTKDLS-LLESDFNNMSFTNADQSTMISNYEKELSDKNKEINDLQNQLKQMTQ 2572

Query: 1553 KIQKHVSFASDTKQGRDEQLDNTMNKE 1579
              +  +   SD      E+  N  N E
Sbjct: 2573 N-RDELQSKSDKLNEEIEEKKNIQNLE 2598



 Score =  174 bits (424), Expect = 1e-41
 Identities = 279/1496 (18%), Positives = 616/1496 (41%), Gaps = 130/1496 (8%)

Query: 142  GDVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXX 201
            G      N ++EK   ++ ++ ++  M++ I   + +I   +Q +  KNK          
Sbjct: 798  GSGNQFENLLQEKLTKIATMEKRINTMKSDIEKQKIEIATLNQDVSDKNKTIQQLQNKLK 857

Query: 202  XXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLE 261
                       +     +++ E  I  E + K E   L   ++ KDV+I +++E  K  E
Sbjct: 858  NKENSVQRLNGEITDLRSRISEYEILNERQAK-ENALLNNKLKQKDVQIENIKEQPKEEE 916

Query: 262  AARFEISLEHSKL-AQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIAN 320
                ++      L  +E +Q               +  +  P  E    + +    +  N
Sbjct: 917  EKPKQVGFAKPSLPPKESDQREFIKGSRSSGQLKFSPIATPPE-ENNNSLSQLEQFKKLN 975

Query: 321  MT------ELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKK--------G 366
             T       L  K   ++ L  ++  +N +L+  + T   E+K +++  K+         
Sbjct: 976  TTIKEQSQRLLAKDRKIDLLKQRLNDSNNQLKEIMET--PENKRIAAKEKELEDFQQQLR 1033

Query: 367  SPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVI---QSLNKDLVD 423
            S +IS+ S   T         Q+  E   +  +     NEI +L  ++   ++L +D + 
Sbjct: 1034 SQIISQSSSFITYENESDAMKQIKEENYRRVVENTHKDNEIIRLTKLLATDKTLKEDKIL 1093

Query: 424  KEYV------ISEKDTXXXXXXXXXXGKDTLIAQLQ-----LEHQ-QHMEGPSLIHVGTN 471
            +E +      + +              K+     LQ     L+ Q Q        H    
Sbjct: 1094 QEKIMQLEAKVQQMKDFNKETAANLESKNLENYNLQDNINSLKEQIQKQNDEQANHQKEL 1153

Query: 472  TEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKS 531
             E   +IA +Q+++++  N  ++   V    EKL ++  ++ +LN+  +   K+ I VK 
Sbjct: 1154 DERDEQIAVLQKEIEKYENRYLEQQEVISQ-EKLNNSNLKL-KLNEAENEIEKSHI-VKQ 1210

Query: 532  NHKLKLKQMQKTIDNFSK--------VSDSNKEIVRLTEELHHLSQKVAE---LEEEKGN 580
              +L L ++ + I  F          ++ SN +I  L  ++   ++++     L+++   
Sbjct: 1211 PGELYLSEVPQQISYFENKVKIMNGMITQSNAKIKELESQIEKKNKQIESTEALQKKSRE 1270

Query: 581  LQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEV 640
            L   + DY+          +++ EME   + +    ++++++  DL Q   IL+ + +++
Sbjct: 1271 LYRQIRDYEQRLSSLGLTVEQIREMEMTIKNQ---ANIIKAKDDDLKQTKEILEYREEQI 1327

Query: 641  EDKLAD--------------ISQL---------QSDQVCSEIKSVH---LEEQIDALSAS 674
            E  +A+              IS+L         +++   +EI+  +   LE+    L  +
Sbjct: 1328 EKFIAESVSIRDAIETLKQRISELEMLLEKKDKENNDKIAEIQEENRQTLEQLAKQLQEA 1387

Query: 675  KKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSA---EK 731
            ++++ ++  N ++ ++++    K +E    DI   L+  I E  +  D L++  A   E+
Sbjct: 1388 EEDINVLEGNCQVYEQEIAEKDKQIEQMTNDI-KSLEEVINEQSNTIDSLKQDVATKEEE 1446

Query: 732  ISELLAKINHEEQSKIQTQFGI---DAKIQERDLYIENIESELSKYKSRICRLEESIAVM 788
            I +L   ++  E+   Q Q  I   DA+IQ+    IE  +  +S+    I +L+  I   
Sbjct: 1447 IKQLKQTVSENEEVIKQLQTDIEQKDAEIQKNKEEIEQHKQTISQRDETIKQLQSEIEQH 1506

Query: 789  EDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHEN 848
            +        + +QL + + E+++   +    ++E+      + + D  ++K   EIE + 
Sbjct: 1507 KQTIADKNNEIEQLKNTISEREETIKQL---QNEIEQHKQTMAERDAEIQKNKEEIEQQK 1563

Query: 849  KELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQL--RDLE-S 905
            + +   N  + +  + +    ++++Q    + E+       ++E  +++  +  RD E  
Sbjct: 1564 QTISNNNNEIEQLKKTISERDAEIEQLKKTIAERDESIKQLQNEIEQHKQTISQRDAEIE 1623

Query: 906  NLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNI----EYVTQLE 961
             LK+   +    I +K+  I+ L+ E   Q +  I DK    E+ ++ +    E + QL+
Sbjct: 1624 QLKQTVQQRDQTIAEKEDLIKQLQSEIE-QHKQTISDKNNEIEQLKQTVNARDEAIKQLQ 1682

Query: 962  AQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYT-EQYINEINKLNALLKQ 1020
            ++++++K  I   +  +++ NK  +E      QKQ     D T +Q  NEI +    + Q
Sbjct: 1683 SEIEQHKQTIAERDAEIQK-NKEEIE-----QQKQTISQRDETIKQLQNEIEQHKQTISQ 1736

Query: 1021 KDEEIIALNQKINNAQVSYM---SMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQH 1077
            +D EI  L Q +  +  +      ++   +S++ Q    +   + E+Q+  +++   KQ 
Sbjct: 1737 RDAEIEQLKQTVQQSDQTIAEKEDLIKQLQSEIEQHKQTIAERDAEIQKNKEEIEQQKQT 1796

Query: 1078 NEELQILVREQDDQIKELKETKLTFEMNIPKTEGMII--SSTIEPMSDDANNVDXXXXXX 1135
              +    +++   +I++ K+T    E  I + +  I    ++I+ + ++           
Sbjct: 1797 ISQRDESIKQMQSEIEQNKQTIADREKEIEQHKQTIAERDNSIKQLQEEIEQ-----HKQ 1851

Query: 1136 XXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQ 1195
                   ++Q+ +E IQ+++   E    L  E +E   KI++LE  N  L        + 
Sbjct: 1852 TIAERDAEIQKNKEEIQQKN---EAINALTNEGEEKRLKILELEANNENLINKVKELNDS 1908

Query: 1196 INQLKSKLEQLNTENDNLLSTVAELRSSI-----SSAVDQRGFEIAELWKQHLAQREADF 1250
            ++ L    E  N+    +   + +L   I      S   Q+  E  +   Q L   +A  
Sbjct: 1909 VSDLNLSTENQNSVVKQMTDEIKDLNKQIHELEVKSENQQKQIEEKDKEIQSLTNTKAQN 1968

Query: 1251 QKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQ 1310
            ++   +L+ ++    +   Q  +++++  ++  +   T  Q   L  K Q++ + L N +
Sbjct: 1969 EELIKKLQEEVENLTNTKNQNEETIKNLQEQVQSLTETKNQNEDLIKKQQEQIQSLTNTK 2028

Query: 1311 EKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQE--QSIL 1368
             +  + I  ++     + + K                      T  +  K+ QE  QS+ 
Sbjct: 2029 NENEETIKNLQEQVQSLTETKATNEETIKKLQGEVQSLTETKATNEEQIKKQQEEIQSLS 2088

Query: 1369 NINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLT 1428
            N   EN +L K              +  +   K+ E    L+ +++E   K +E+   L+
Sbjct: 2089 NTKNENEELIKKLQEEIQNLTNTKTQNEEQIKKLQEEIQNLQKQNAEKDDKINEFNAKLS 2148

Query: 1429 QRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLI 1488
              +   + +  + +  +  I  LT ++ +E   L  ++++  +  E  + + E E+ +LI
Sbjct: 2149 TLSSSSDELTTKFINAQNEINQLT-KQNNEKDNLISQLNQKISDLENAKSQLENEKSQLI 2207

Query: 1489 EELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQ 1544
            +E     T       Q+ E  K LEEE  K    +T LE ++ +++   +E TNL+
Sbjct: 2208 QEK----TNLEQEKAQLLEQKKNLEEEKQKLETEKTNLEQEKAKLI---EEKTNLE 2256



 Score =  171 bits (415), Expect = 2e-40
 Identities = 306/1526 (20%), Positives = 632/1526 (41%), Gaps = 133/1526 (8%)

Query: 152  KEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKN-KATTXXXXXXXXXXXXXXXX 210
            +EKD A+S LQ +++   T I   +EKI++  + IEAK+ K                   
Sbjct: 500  EEKDKAISKLQKQIERQNTIIQQNEEKIDQLSKDIEAKDQKIDEMIQKSLTAEVPSGDGA 559

Query: 211  XEDTKQQMTKMQENFIAMEAE---WKDEKQRLLKDIESK-DVRISSLEEA---------N 257
              + K Q      ++IA++ E    KD K   L+D   K D +IS L             
Sbjct: 560  ALELKLQNL---NSYIAIQNEKMGQKDAKIEQLEDERQKNDTKISELTSTLTQLKLTNNE 616

Query: 258  KLLEAARFEISLEHSKLAQ--------ELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTE 309
              L+ A  E ++  S + +        E+ Q              + K   E     + E
Sbjct: 617  NTLKIAELENTIAKSNIPKKEGELYLSEVPQEVSFLKNKNNMLNNINKSQAEKIKHLEQE 676

Query: 310  IEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPL 369
            I +K   +I ++ E+ KK   L+    QI+    +L  +    G E+ A     K+ S L
Sbjct: 677  IVKKNK-QIGSIDEMHKKSRELQR---QIQDYENKLNAQQLESGGENSAELLSLKQQSNL 732

Query: 370  ISRKSG--RNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYV 427
            +++     +    ++K        +  +  +D  + K+ ++++   + S NK + D E  
Sbjct: 733  LNQLVADLKKQNIELKKTLETKDKQLSSMMSDSLLVKDNLSEITAELASKNKIIHDYELR 792

Query: 428  ISEKDTXXXXXXXXXXGKDTLIAQLQ--LEHQQHMEGPSLIHVGTNTEDVNE----IAKV 481
            ++               K T IA ++  +   +       I + T  +DV++    I ++
Sbjct: 793  LNALSGSGNQFENLLQEKLTKIATMEKRINTMKSDIEKQKIEIATLNQDVSDKNKTIQQL 852

Query: 482  QEQLK------QELNDEIKDVNVK----DLIEKLKSAEEQITQLNDEI---DAANKNMIK 528
            Q +LK      Q LN EI D+  +    +++ + ++ E  +  LN+++   D   +N+ +
Sbjct: 853  QNKLKNKENSVQRLNGEITDLRSRISEYEILNERQAKENAL--LNNKLKQKDVQIENIKE 910

Query: 529  VKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLS-QKVAELEEEKGNLQLHLVD 587
                 + K KQ+     +        +E ++ +     L    +A   EE  N    L  
Sbjct: 911  QPKEEEEKPKQVGFAKPSLPPKESDQREFIKGSRSSGQLKFSPIATPPEENNNSLSQLEQ 970

Query: 588  YDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADI 647
            +        +  ++++  +   +   + ++   +Q  ++++      ++    E +L D 
Sbjct: 971  FKKLNTTIKEQSQRLLAKDRKIDLLKQRLNDSNNQLKEIMETPE--NKRIAAKEKELEDF 1028

Query: 648  SQLQSDQVCSEIKS-VHLEEQIDALSASKKE-LALVIENLKLDKE-----QLYGTIKDLE 700
             Q    Q+ S+  S +  E + DA+   K+E    V+EN   D E     +L  T K L+
Sbjct: 1029 QQQLRSQIISQSSSFITYENESDAMKQIKEENYRRVVENTHKDNEIIRLTKLLATDKTLK 1088

Query: 701  NDK---EDIMN---KLQNYIQENMDLTDKLEKMSAE--KISELLAKINHEEQSKIQTQFG 752
             DK   E IM    K+Q     N +    LE  + E   + + +  +  + Q +   Q  
Sbjct: 1089 EDKILQEKIMQLEAKVQQMKDFNKETAANLESKNLENYNLQDNINSLKEQIQKQNDEQAN 1148

Query: 753  IDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQE---- 808
               ++ ERD  I  ++ E+ KY++R    +E I+  +    +L+ K ++  + +++    
Sbjct: 1149 HQKELDERDEQIAVLQKEIEKYENRYLEQQEVISQEKLNNSNLKLKLNEAENEIEKSHIV 1208

Query: 809  KQKA---YSEYTIQEDELVNRLAV---LMDHDRVVEKQL-LEIEHENKELQKKNQILLEE 861
            KQ      SE   Q     N++ +   ++       K+L  +IE +NK+++   + L ++
Sbjct: 1209 KQPGELYLSEVPQQISYFENKVKIMNGMITQSNAKIKELESQIEKKNKQIE-STEALQKK 1267

Query: 862  NQNLQISLSDMQQHYNAL---VEKANRTDLA-ESESTKYQTQLRDLESNLKRITHEHQTL 917
            ++ L   + D +Q  ++L   VE+    ++  ++++   + +  DL+   + + +  + +
Sbjct: 1268 SRELYRQIRDYEQRLSSLGLTVEQIREMEMTIKNQANIIKAKDDDLKQTKEILEYREEQI 1327

Query: 918  ------IVQKKKEIEDLEIEFNTQIESAIRDK-KVLNEK----YEKNIEYVTQLEAQLQE 966
                   V  +  IE L+    +++E  +  K K  N+K     E+N + + QL  QLQE
Sbjct: 1328 EKFIAESVSIRDAIETLKQRI-SELEMLLEKKDKENNDKIAEIQEENRQTLEQLAKQLQE 1386

Query: 967  YKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQ----KD 1022
             + +I  L  N  ++ +  +   DK ++ Q T      E+ INE +     LKQ    K+
Sbjct: 1387 AEEDINVLEGNC-QVYEQEIAEKDKQIE-QMTNDIKSLEEVINEQSNTIDSLKQDVATKE 1444

Query: 1023 EEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQ 1082
            EEI  L Q ++  +     + +D E K A+     E +E+  Q +S++    KQ   E++
Sbjct: 1445 EEIKQLKQTVSENEEVIKQLQTDIEQKDAEIQKNKEEIEQHKQTISQRDETIKQLQSEIE 1504

Query: 1083 ---ILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDA----NNVDXXXXXX 1135
                 + +++++I++LK T    E  I + +  I          DA    N  +      
Sbjct: 1505 QHKQTIADKNNEIEQLKNTISEREETIKQLQNEIEQHKQTMAERDAEIQKNKEEIEQQKQ 1564

Query: 1136 XXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKI-IQLETLNTELTGHDVVNQE 1194
                   ++++ ++ I ER    EQ  K   E  E   ++  ++E     ++  D    E
Sbjct: 1565 TISNNNNEIEQLKKTISERDAEIEQLKKTIAERDESIKQLQNEIEQHKQTISQRD-AEIE 1623

Query: 1195 QINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTE 1254
            Q+ Q   + +Q   E ++L+  +          +  +  EI +L KQ +  R+   ++ +
Sbjct: 1624 QLKQTVQQRDQTIAEKEDLIKQLQSEIEQHKQTISDKNNEIEQL-KQTVNARDEAIKQLQ 1682

Query: 1255 HELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYA 1314
             E+         +  ++  + +   Q++       E +  LQN++   E+H + + ++ A
Sbjct: 1683 SEIEQHKQTIAERDAEIQKNKEEIEQQKQTISQRDETIKQLQNEI---EQHKQTISQRDA 1739

Query: 1315 DV--INQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINE 1372
            ++  + Q      +   EK                   +   E Q  K+  EQ    I++
Sbjct: 1740 EIEQLKQTVQQSDQTIAEKEDLIKQLQSEIEQHKQTIAERDAEIQKNKEEIEQQKQTISQ 1799

Query: 1373 ENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRND 1432
             +  +K+              R  + E     +  + +    ++ ++  ++  T+ +R+ 
Sbjct: 1800 RDESIKQMQSEIEQNKQTIADREKEIEQHKQTIAER-DNSIKQLQEEIEQHKQTIAERDA 1858

Query: 1433 EFENVRQQLVEYEKRIEDLTYE-KESELAILRLKMHENANHYETMQKESEIERVKLIEEL 1491
            E +  ++++ +  + I  LT E +E  L IL L+    AN+   + K  E+     + +L
Sbjct: 1859 EIQKNKEEIQQKNEAINALTNEGEEKRLKILELE----ANNENLINKVKELN--DSVSDL 1912

Query: 1492 NVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASS 1551
            N+      S+ KQ+ +  K L +++   +E++   ENQ+ +I   + EI +L N    + 
Sbjct: 1913 NLSTENQNSVVKQMTDEIKDLNKQI---HELEVKSENQQKQIEEKDKEIQSLTNTKAQNE 1969

Query: 1552 ---SKIQKHVSFASDTKQGRDEQLDN 1574
                K+Q+ V   ++TK   +E + N
Sbjct: 1970 ELIKKLQEEVENLTNTKNQNEETIKN 1995



 Score =  157 bits (381), Expect = 2e-36
 Identities = 304/1497 (20%), Positives = 646/1497 (43%), Gaps = 156/1497 (10%)

Query: 147  LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXX 206
            L++  K+KD+ ++ L  +MK ++ T+   QE++ E    ++   +               
Sbjct: 2824 LNDQNKQKDSQINQLNNEMKELQQTLKQTQEQLKETQDQLKQTQETLATKEKEFAKSAED 2883

Query: 207  XXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEE-ANKLLEAARF 265
                 +  +Q +  +Q N    +AE  D KQ+L    E+K    + L++ A   + + R 
Sbjct: 2884 LNNELKKKQQAIDDLQNNLKQKDAELTDTKQKL----EAKTNEFNDLKQKAENEIASLRK 2939

Query: 266  EISLEHSKLA---QELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMT 322
            EI    +KLA   +ELE               L K ++    E    ++ +     A   
Sbjct: 2940 EIEQLKAKLANTSKELEASKSESDLQKKENDKL-KVNLAKIAEMYKTLKSESENNSAKSN 2998

Query: 323  ELTKKI-ELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASK 381
            +  K++ E +++L  Q+ +     EN       + + +   +KK   L+  +S ++  + 
Sbjct: 2999 DKIKQMQEKIQNLEIQVEKMKLANENLTNENKLQKETIEMLNKK---LL--ESNKSLTAS 3053

Query: 382  MKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXX 441
            +K        ETL ++ +  + K++I KL   +Q L +D    +   +E D+        
Sbjct: 3054 IKE------YETLKRENN--LQKDQITKLTSQVQKLTQDFTQLKKEKAEVDSKLNELLDL 3105

Query: 442  XXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDL 501
               KD  I +L+ E+Q+  E    I     T+D+ E    +E L Q  N+    +++ +L
Sbjct: 3106 LAQKDKEIERLKSENQKLNELYQQI-----TKDLEE----KEFLIQSQNNRC--IDLLNL 3154

Query: 502  IEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFS-KVSDSNKEIV-- 558
             EK K+ E +  Q+++  D+ N ++ K     +++L++    ++N   K+++SN+++   
Sbjct: 3155 TEK-KNKEIETLQISN--DSLNNSLTK----SQMELREKSTLLENAKDKITESNRKLALF 3207

Query: 559  -RLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAIS 617
             RL+     L+   +    +K +      D DS   I +   + +I +E   +     + 
Sbjct: 3208 DRLSANSSELNLTSSGRGIKKSSSMNLSTDMDSKNKIINQQEQTIIGLEQSLKVSKNEV- 3266

Query: 618  LLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQ-IDALSASK- 675
              ++ K +L ++L   ++  ++++      ++L++ ++ S +K ++ ++Q ID+L +S  
Sbjct: 3267 --DATKRELQKQLQNNKELQNQIKMTKEQFAKLEA-KLQSVVKKLNDKDQRIDSLMSSDP 3323

Query: 676  -----KELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDL--------TD 722
                  +L   I +L L+ E+L   +  +  + + + + L++   +   L        T+
Sbjct: 3324 NNKQTNQLNKQISDLNLENEKLKTRVDIITRENQSLKDDLESQKSQKSKLDESCNALKTE 3383

Query: 723  KLEKMSA-----EKISELLAKIN--HEEQSKIQTQFGIDAKIQERDLYIENIESE--LSK 773
             + K S      EK+ EL+ +IN  +++ S+++ +F   +  ++R  Y++ IE E  +++
Sbjct: 3384 LINKKSIMDQYKEKLKELMEQINLKNKQISELKAEFN-GSDDEDRKSYVKVIEQEGEITE 3442

Query: 774  YKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQ-EDELVN-RLAVLM 831
             K  I R ++ +   + +   LE+   +     Q+  K       + ED   N    + M
Sbjct: 3443 LKVIIDRQKKFVGQQKMKIADLEKNLKESNDEAQKMTKNLQTTIYELEDRCQNLNQTIEM 3502

Query: 832  DHDRVVEKQLLEIEHENKE---LQKKNQILLEE---------NQNLQISLSDMQQHYNAL 879
             + R+ E +   IE  NKE   L+ K  IL  E           NL   +  +Q+  +  
Sbjct: 3503 KNFRLRENEKT-IEDLNKEIEFLKGKIDILSREISMYSDNSSKDNLISKIVSLQKTVSEK 3561

Query: 880  VEKANRTDLAESESTKYQTQLR-DLESNLKRITH-EHQTLIVQKK------KEIEDLEIE 931
             E+ N   +  + S + + +++ +++    RI H E+Q  ++  K      KE   ++I+
Sbjct: 3562 DEQLNDAKINSNNSLEIEDKMQQEIDQKNSRIHHLENQMRVLLNKASHENAKEESKVKID 3621

Query: 932  F---NTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENL-NMNVEELNKMNLE 987
                N ++ +   D   L E+       V++LE  ++E ++ I  +   N  ++N+++ E
Sbjct: 3622 LKKANVKLSNLENDFSSLQEENAALKSKVSKLELVIKEKQSEINIMAQKNNNDINEIS-E 3680

Query: 988  LIDKHVQKQQ---TQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVS 1044
            L  K ++KQ    TQ     E+  +EI++L   LK K+ E+     +I   +     +  
Sbjct: 3681 LKSK-LRKQNEDFTQEKSSAEKQRSEIDQLTNDLKAKNNELDDSKSEIRILKSKINQLQQ 3739

Query: 1045 DYESK---LAQFTTKLENMEEEMQRVSKQLLDSKQHNEE-----LQILVREQDDQIKELK 1096
            D+++K   L + + KL  +EE+M+    +LL+    N++     ++ L  E  +Q K+LK
Sbjct: 3740 DFDAKNHSLQKESEKLSQLEEKMKEKELELLNKSLDNDKAAKEIIEKLQNENLEQSKQLK 3799

Query: 1097 ETKLTFE-----MNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFI 1151
            + +   E     +N    E   +   I  + +D   +             L  ++ EE +
Sbjct: 3800 KKEKDIEQMKQILNDLNNEQGELKGKIMTLQNDNEQI----TKTSQEKFKLNEKKSEELV 3855

Query: 1152 QERSVLQEQSAKLNTELQ-ECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTEN 1210
               + L ++ A+ N  +      K  ++  L  +L    + N E+I  L+S++ ++   N
Sbjct: 3856 SMINKLNDEIAEKNKTINGTLLQKEKEITKLKNDLEQSQITN-ERITNLESEMMKMKQLN 3914

Query: 1211 DNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQ 1270
            D+L++ +      +     ++  E+ EL ++ L Q   + QK   E        + K  +
Sbjct: 3915 DDLMNDINRYNEELI----EKENELQEL-REKLIQSGNNLQKVTPEQ--SYFDLQMKITE 3967

Query: 1271 LLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADV-INQIEILRSEIED 1329
            L D ++    +  NK     ++T+L +KL +      + + +   + + ++ I  +E+E+
Sbjct: 3968 LEDIIKDKNSQLENKT---NEITNLYSKLYNTSPPSNSKKPRNTKLEVEKMRIKMAELEN 4024

Query: 1330 EKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXX 1389
            +                          +  K  +      IN+ N +L+K          
Sbjct: 4025 KNKDLIDQNTRMNSDLQAQINQNNKLKRHMKDNENNFNSQINQLNLKLQKVVSDYEARLL 4084

Query: 1390 XXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYT------------ITLTQR-NDEFEN 1436
                  N  + +V EL  +++ K+ EI  K  +              I L+++ N++  N
Sbjct: 4085 ILDNSKNQTQ-RVNELRERIKQKNEEILSKEKQINENKLENDKLKNEIELSKKQNEDLSN 4143

Query: 1437 VRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKIT 1496
               Q     K +E      + + A +  +++++ N  E + K S IER  L E+LN  + 
Sbjct: 4144 YLSQKEAKIKELERRIQSLDEQNAKIEDELNKSINKNEEINKSSIIERTDLSEQLNNALK 4203

Query: 1497 ESVSLNKQVAELNKALEEEVAKTNEMQTA--LENQEIEI----VTLNDEITNLQNMV 1547
            E+  L  Q+ E    ++E   K +++     + +Q I++      L D+   L+NM+
Sbjct: 4204 ENSRLKVQIDETVSKIKELCDKDSDIARVKLVSDQLIDLSEYCKLLKDQNEELKNMI 4260



 Score =  155 bits (375), Expect = 1e-35
 Identities = 279/1583 (17%), Positives = 652/1583 (41%), Gaps = 127/1583 (8%)

Query: 94   LANTLKQKEILMEKI-KQYKELSKRSSTTIVRXXXXXXXXXXXXXX-----XQL--GDVT 145
            L+  L+QK   +E + K++ +L ++S  TI +                    QL   +V 
Sbjct: 2622 LSAQLQQKTQELENLTKEFNDLKQKSEQTIAQNNEEIANLKKNVAERDKKISQLLENEVN 2681

Query: 146  HLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKD-QIIEAKNKATTXXXXXXXXXX 204
             L   + +K+N  + L+  +   E  I +L++ +++K+ +I + KN  T           
Sbjct: 2682 ELKKKLSDKENENTSLKNTISERENEINNLKKNVSDKENEINQLKNNLTMRETELNKMKD 2741

Query: 205  XXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAAR 264
                   ++ KQ + +  ++   +  ++ D    L K  +        +E  NK +E  +
Sbjct: 2742 EEV----KNAKQIIAQKDKDLEELNGKFNDTNNNLSKANDELKQLKEQIESLNKQIEQMK 2797

Query: 265  FEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTEL 324
               +L+ S++ Q                    K+  + + ++ ++I +  + E+  + + 
Sbjct: 2798 CSNNLKESEIKQ--------LTSNLQKYKQALKELNDQNKQKDSQINQLNN-EMKELQQT 2848

Query: 325  TKKI-ELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLIS--RKSGRNTASK 381
             K+  E L+    Q++QT + L  K       ++ +++  KK    I   + + +   ++
Sbjct: 2849 LKQTQEQLKETQDQLKQTQETLATKEKEFAKSAEDLNNELKKKQQAIDDLQNNLKQKDAE 2908

Query: 382  MKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXX 441
            +     +L ++T   +  K+  +NEIA L   I+ L   L +     + K+         
Sbjct: 2909 LTDTKQKLEAKTNEFNDLKQKAENEIASLRKEIEQLKAKLAN-----TSKELEASKSESD 2963

Query: 442  XXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDL 501
               K+    ++ L     M      +    +E  N  AK  +++KQ + ++I+++ ++  
Sbjct: 2964 LQKKENDKLKVNLAKIAEM------YKTLKSESENNSAKSNDKIKQ-MQEKIQNLEIQ-- 3014

Query: 502  IEKLKSAEEQITQLN----DEIDAANKNMIKVKSNHKLKLKQMQ--KTIDNFSK--VSDS 553
            +EK+K A E +T  N    + I+  NK +++   +    +K+ +  K  +N  K  ++  
Sbjct: 3015 VEKMKLANENLTNENKLQKETIEMLNKKLLESNKSLTASIKEYETLKRENNLQKDQITKL 3074

Query: 554  NKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSG-RMIESDVYKKMIEMENLAETR 612
              ++ +LT++   L ++ AE++ +   L   L   D     ++S+  K     + + +  
Sbjct: 3075 TSQVQKLTQDFTQLKKEKAEVDSKLNELLDLLAQKDKEIERLKSENQKLNELYQQITKDL 3134

Query: 613  LKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEI----KSVHLEEQI 668
             +   L++SQ    +  L++ ++K  E+E        L +    S++    KS  LE   
Sbjct: 3135 EEKEFLIQSQNNRCIDLLNLTEKKNKEIETLQISNDSLNNSLTKSQMELREKSTLLENAK 3194

Query: 669  DALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMS 728
            D ++ S ++LAL  + L  +  +L  T       K   MN     +  +MD  +K+    
Sbjct: 3195 DKITESNRKLAL-FDRLSANSSELNLTSSGRGIKKSSSMN-----LSTDMDSKNKIINQQ 3248

Query: 729  AEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVM 788
             + I  L   +   +     T+  +  ++Q        I+    ++     +L+  +  +
Sbjct: 3249 EQTIIGLEQSLKVSKNEVDATKRELQKQLQNNKELQNQIKMTKEQFAKLEAKLQSVVKKL 3308

Query: 789  EDRRYSLER--KADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEH 846
             D+   ++    +D       +  K  S+  ++ ++L  R+ ++   ++ ++  L   + 
Sbjct: 3309 NDKDQRIDSLMSSDPNNKQTNQLNKQISDLNLENEKLKTRVDIITRENQSLKDDLESQKS 3368

Query: 847  ENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKAN---------RTDLAESESTKYQ 897
            +  +L +    L  E  N +  +   ++    L+E+ N         + +   S+    +
Sbjct: 3369 QKSKLDESCNALKTELINKKSIMDQYKEKLKELMEQINLKNKQISELKAEFNGSDDEDRK 3428

Query: 898  TQLRDLE-----SNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEK-YE 951
            + ++ +E     + LK I    +  + Q+K +I DLE       + A +  K L    YE
Sbjct: 3429 SYVKVIEQEGEITELKVIIDRQKKFVGQQKMKIADLEKNLKESNDEAQKMTKNLQTTIYE 3488

Query: 952  -----KNIEYVTQLEA-QLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTE 1005
                 +N+    +++  +L+E +  IE+LN  +E L K  ++++ + +      S    +
Sbjct: 3489 LEDRCQNLNQTIEMKNFRLRENEKTIEDLNKEIEFL-KGKIDILSREISMYSDNSSK--D 3545

Query: 1006 QYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQ 1065
              I++I  L   + +KDE++       NN+    + +    + ++ Q  +++ ++E +M+
Sbjct: 3546 NLISKIVSLQKTVSEKDEQLNDAKINSNNS----LEIEDKMQQEIDQKNSRIHHLENQMR 3601

Query: 1066 -RVSKQLLDSKQHNEELQILVREQDDQIKELKE--TKLTFEMNIPKTEGMIISSTIEPMS 1122
              ++K   ++ +   +++I +++ + ++  L+   + L  E    K++   +   I+   
Sbjct: 3602 VLLNKASHENAKEESKVKIDLKKANVKLSNLENDFSSLQEENAALKSKVSKLELVIKEKQ 3661

Query: 1123 DDANNVDXXXXXXXXXXXXLKVQ---EEEEFIQERSVLQEQSAKLNTELQECYTKIIQLE 1179
             + N +             LK +   + E+F QE+S  ++Q ++++    +   K  +L+
Sbjct: 3662 SEINIMAQKNNNDINEISELKSKLRKQNEDFTQEKSSAEKQRSEIDQLTNDLKAKNNELD 3721

Query: 1180 TLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELW 1239
               +E+     + + +INQL+   +  N    + L   +E  S +   + ++  E+    
Sbjct: 3722 DSKSEIR----ILKSKINQLQQDFDAKN----HSLQKESEKLSQLEEKMKEKELELLNKS 3773

Query: 1240 KQHLAQREADFQKTEHELRVQLSAFESK------YEQLLDSVQSSTQEETNKIVTM---- 1289
              +    +   +K ++E   Q    + K       +Q+L+ + +   E   KI+T+    
Sbjct: 3774 LDNDKAAKEIIEKLQNENLEQSKQLKKKEKDIEQMKQILNDLNNEQGELKGKIMTLQNDN 3833

Query: 1290 EQVTSLQN---KLQDKE-EHLRNLQEKYADVINQIE--ILRSEIEDEK-VAFXXXXXXXX 1342
            EQ+T       KL +K+ E L ++  K  D I +    I  + ++ EK +          
Sbjct: 3834 EQITKTSQEKFKLNEKKSEELVSMINKLNDEIAEKNKTINGTLLQKEKEITKLKNDLEQS 3893

Query: 1343 XXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKV 1402
                    +L +E    KQ+ +  + +IN  N +L +                N+ +   
Sbjct: 3894 QITNERITNLESEMMKMKQLNDDLMNDINRYNEELIEKENELQELREKLIQSGNNLQKVT 3953

Query: 1403 LELTH-QLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKES-ELA 1460
             E ++  L++K +E+     +    L  + +E  N+  +L                 E+ 
Sbjct: 3954 PEQSYFDLQMKITELEDIIKDKNSQLENKTNEITNLYSKLYNTSPPSNSKKPRNTKLEVE 4013

Query: 1461 ILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTN 1520
             +R+KM E     E   K+   +  ++  +L  +I ++  L + + +       ++ + N
Sbjct: 4014 KMRIKMAE----LENKNKDLIDQNTRMNSDLQAQINQNNKLKRHMKDNENNFNSQINQLN 4069

Query: 1521 -EMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKE 1579
             ++Q  + + E  ++ L++     Q +        QK+    S  KQ  + +L+N   K 
Sbjct: 4070 LKLQKVVSDYEARLLILDNSKNQTQRVNELRERIKQKNEEILSKEKQINENKLENDKLKN 4129

Query: 1580 LLDAVPRAELDLAMYMLHQRDVR 1602
             ++   +   DL+ Y L Q++ +
Sbjct: 4130 EIELSKKQNEDLSNY-LSQKEAK 4151



 Score =  152 bits (369), Expect = 7e-35
 Identities = 303/1522 (19%), Positives = 646/1522 (42%), Gaps = 164/1522 (10%)

Query: 144  VTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQII-EAKNKATTXXXXXXXX 202
            V  L + I+ KD  +  L+ ++   + TI DL+  ++ K++ I + +NK           
Sbjct: 436  VDELKSIIRNKDKQIIELESEIDNQKATIEDLKIDVDFKERTISDLENKINVSANPDKGI 495

Query: 203  XXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEA 262
                       +K Q    ++N I  + E K +  +L KDIE+KD +I  + + +   E 
Sbjct: 496  ELLKEEKDKAISKLQKQIERQNTIIQQNEEKID--QLSKDIEAKDQKIDEMIQKSLTAEV 553

Query: 263  ARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMT 322
               + +    KL Q L                +A Q+ E   ++  +IE+   LE     
Sbjct: 554  PSGDGAALELKL-QNLN-------------SYIAIQN-EKMGQKDAKIEQ---LEDERQK 595

Query: 323  ELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKM 382
              TK  EL   L  Q++ TN E   K+A +       + P K+G   +S      +  K 
Sbjct: 596  NDTKISELTSTLT-QLKLTNNENTLKIAELENTIAKSNIPKKEGELYLSEVPQEVSFLKN 654

Query: 383  KSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXX 442
            K       +  LN      INK++  K    I+ L +++V K   I   D          
Sbjct: 655  K-------NNMLN-----NINKSQAEK----IKHLEQEIVKKNKQIGSIDEMHKKSR--- 695

Query: 443  XGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLI 502
                 L  Q+Q +++  +    L   G N+ ++  + K Q  L  +L  ++K  N+ +L 
Sbjct: 696  ----ELQRQIQ-DYENKLNAQQLESGGENSAELLSL-KQQSNLLNQLVADLKKQNI-ELK 748

Query: 503  EKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTE 562
            + L++ ++Q++ +  +      N+ ++ +    K K +       + +S S  +   L +
Sbjct: 749  KTLETKDKQLSSMMSDSLLVKDNLSEITAELASKNKIIHDYELRLNALSGSGNQFENLLQ 808

Query: 563  E-LHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLES 621
            E L  ++     +   K +++   ++  +     SD  K + +++N  + +  ++  L  
Sbjct: 809  EKLTKIATMEKRINTMKSDIEKQKIEIATLNQDVSDKNKTIQQLQNKLKNKENSVQRLNG 868

Query: 622  QKFDL---VQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQ---------ID 669
            +  DL   + E  IL ++  + E+ L +    Q D     IK    EE+           
Sbjct: 869  EITDLRSRISEYEILNERQAK-ENALLNNKLKQKDVQIENIKEQPKEEEEKPKQVGFAKP 927

Query: 670  ALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSA 729
            +L   + +    I+  +   +  +  I     +  + +++L+ + + N  + ++ +++ A
Sbjct: 928  SLPPKESDQREFIKGSRSSGQLKFSPIATPPEENNNSLSQLEQFKKLNTTIKEQSQRLLA 987

Query: 730  E--KISELLAKIN-HEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIA 786
            +  KI  L  ++N    Q K   +   + +I  ++  +E+ + +L   +S+I     S  
Sbjct: 988  KDRKIDLLKQRLNDSNNQLKEIMETPENKRIAAKEKELEDFQQQL---RSQIISQSSSF- 1043

Query: 787  VMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVL-----MDHDRVVEKQL 841
                   + E ++D +    +E  +   E T +++E++    +L     +  D+++++++
Sbjct: 1044 ------ITYENESDAMKQIKEENYRRVVENTHKDNEIIRLTKLLATDKTLKEDKILQEKI 1097

Query: 842  LEIE---HENKELQKKNQILLE----ENQNLQISLSDM-QQHYNALVEKANRTDLAESES 893
            +++E    + K+  K+    LE    EN NLQ +++ + +Q      E+AN     +   
Sbjct: 1098 MQLEAKVQQMKDFNKETAANLESKNLENYNLQDNINSLKEQIQKQNDEQANHQKELDERD 1157

Query: 894  TKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYE-- 951
             +     +++E    R   E Q +I Q+K    +L+++ N + E+ I    ++ +  E  
Sbjct: 1158 EQIAVLQKEIEKYENRYL-EQQEVISQEKLNNSNLKLKLN-EAENEIEKSHIVKQPGELY 1215

Query: 952  -----KNIEY-----------VTQLEAQLQEYKNNIENLNMNVEE---LNKMNLELIDK- 991
                 + I Y           +TQ  A+++E ++ IE  N  +E    L K + EL  + 
Sbjct: 1216 LSEVPQQISYFENKVKIMNGMITQSNAKIKELESQIEKKNKQIESTEALQKKSRELYRQI 1275

Query: 992  HVQKQQTQSPDYTEQYINEI-----NKLNALLKQKDE------EIIALN----QKINNAQ 1036
               +Q+  S   T + I E+     N+ N ++K KD+      EI+       +K     
Sbjct: 1276 RDYEQRLSSLGLTVEQIREMEMTIKNQAN-IIKAKDDDLKQTKEILEYREEQIEKFIAES 1334

Query: 1037 VSYMSMVSDYESKLAQFTTKLENMEEE-MQRVSKQLLDSKQHNEELQILVREQDDQIKEL 1095
            VS    +   + ++++    LE  ++E   ++++   +++Q  E+L   ++E ++ I  L
Sbjct: 1335 VSIRDAIETLKQRISELEMLLEKKDKENNDKIAEIQEENRQTLEQLAKQLQEAEEDINVL 1394

Query: 1096 KETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLK---VQEEEEFIQ 1152
            +     +E  I + +       IE M++D  +++            LK     +EEE  Q
Sbjct: 1395 EGNCQVYEQEIAEKD-----KQIEQMTNDIKSLEEVINEQSNTIDSLKQDVATKEEEIKQ 1449

Query: 1153 ERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGH-DVVNQ--EQINQLKSKLEQLNTE 1209
             +  + E    +     +   K  +++    E+  H   ++Q  E I QL+S++EQ    
Sbjct: 1450 LKQTVSENEEVIKQLQTDIEQKDAEIQKNKEEIEQHKQTISQRDETIKQLQSEIEQHKQT 1509

Query: 1210 NDNLLSTVAELRSSIS---SAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQ---LSA 1263
              +  + + +L+++IS     + Q   EI E  KQ +A+R+A+ QK + E+  Q   +S 
Sbjct: 1510 IADKNNEIEQLKNTISEREETIKQLQNEI-EQHKQTMAERDAEIQKNKEEIEQQKQTISN 1568

Query: 1264 FESKYEQLLDSVQSSTQE-ETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADV--INQI 1320
              ++ EQL  ++     E E  K    E+  S++    + E+H + + ++ A++  + Q 
Sbjct: 1569 NNNEIEQLKKTISERDAEIEQLKKTIAERDESIKQLQNEIEQHKQTISQRDAEIEQLKQT 1628

Query: 1321 EILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQ---MQEQSILNINEENAQL 1377
               R +   EK                   D   E +  KQ    ++++I  +  E  Q 
Sbjct: 1629 VQQRDQTIAEKEDLIKQLQSEIEQHKQTISDKNNEIEQLKQTVNARDEAIKQLQSEIEQH 1688

Query: 1378 KKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENV 1437
            K++              +   +  + +    ++   +EI Q  H+ TI  +QR+ E E +
Sbjct: 1689 KQTIAERDAEIQKNKEEIEQQKQTISQRDETIKQLQNEIEQ--HKQTI--SQRDAEIEQL 1744

Query: 1438 RQQLVEYEKRI---EDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIE-ELNV 1493
            +Q + + ++ I   EDL  + +SE+   +  + E     +  ++E E ++  + + + ++
Sbjct: 1745 KQTVQQSDQTIAEKEDLIKQLQSEIEQHKQTIAERDAEIQKNKEEIEQQKQTISQRDESI 1804

Query: 1494 KITES-VSLNKQ-VAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASS 1551
            K  +S +  NKQ +A+  K +E+      E   +++  + EI      I      ++ + 
Sbjct: 1805 KQMQSEIEQNKQTIADREKEIEQHKQTIAERDNSIKQLQEEIEQHKQTIAERDAEIQKNK 1864

Query: 1552 SKI-QKHVSFASDTKQGRDEQL 1572
             +I QK+ +  + T +G +++L
Sbjct: 1865 EEIQQKNEAINALTNEGEEKRL 1886



 Score =  124 bits (299), Expect = 2e-26
 Identities = 231/1150 (20%), Positives = 494/1150 (42%), Gaps = 99/1150 (8%)

Query: 464  SLIHVGTNTEDVNEIAKVQEQL------KQELNDEIKDVNVKDLIEKLKSAEEQ--ITQL 515
            S +H   N +   E+ K++EQ+      K E   +++ V   + + + K +E Q  + QL
Sbjct: 289  SNLHELDNNQLQGELIKLREQILELSKQKSETESKLEWVEQSNKLLQSKPSENQQILDQL 348

Query: 516  ND----EIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNK--EIVRLTEELHHLSQ 569
            N     EID   K++ ++ +  KL   + QK ID+  K+ +S+   E   L +E ++L  
Sbjct: 349  NTLRQKEIDEQQKHVEELTNQEKLAESEYQKQIDHLKKLLESSNAAETENLRKENNNLRD 408

Query: 570  KVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQE 629
            ++A +   K     ++++ +       D+  K+ E++++   + K I  LES+  +    
Sbjct: 409  QLAAIASNK-----NILENEEILTSNFDLSDKVDELKSIIRNKDKQIIELESEIDNQKAT 463

Query: 630  LHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHL--EEQIDALSASKKELALVIENLKL 687
            +  L+   D  E  ++D+   + +   +  K + L  EE+  A+S  +K++      ++ 
Sbjct: 464  IEDLKIDVDFKERTISDLEN-KINVSANPDKGIELLKEEKDKAISKLQKQIERQNTIIQQ 522

Query: 688  DKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKI 747
            ++E++    KD+E   +    K+   IQ++  LT ++       +   L  +N    S I
Sbjct: 523  NEEKIDQLSKDIEAKDQ----KIDEMIQKS--LTAEVPSGDGAALELKLQNLN----SYI 572

Query: 748  QTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQ 807
              Q   + K+ ++D  IE +E E  K  ++I  L  ++  ++        K  +L + + 
Sbjct: 573  AIQ---NEKMGQKDAKIEQLEDERQKNDTKISELTSTLTQLKLTNNENTLKIAELENTIA 629

Query: 808  EKQKAYSEYTIQEDELVNRLAVLMDHDRVV----EKQLLEIEHENKELQKKN-QI----- 857
            +      E  +   E+   ++ L + + ++    + Q  +I+H  +E+ KKN QI     
Sbjct: 630  KSNIPKKEGELYLSEVPQEVSFLKNKNNMLNNINKSQAEKIKHLEQEIVKKNKQIGSIDE 689

Query: 858  LLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQ-LRDLESNLKRITHEHQT 916
            + ++++ LQ  + D +   NA   ++   + AE  S K Q+  L  L ++LK+   E + 
Sbjct: 690  MHKKSRELQRQIQDYENKLNAQQLESGGENSAELLSLKQQSNLLNQLVADLKKQNIELKK 749

Query: 917  LIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNM 976
             +  K K++  +  +     ++       L  K +   +Y  +L A L    N  ENL  
Sbjct: 750  TLETKDKQLSSMMSDSLLVKDNLSEITAELASKNKIIHDYELRLNA-LSGSGNQFENLLQ 808

Query: 977  NVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQ 1036
              E+L K  +  ++K +    T   D  +Q I EI  LN  +  K++ I  L  K+ N +
Sbjct: 809  --EKLTK--IATMEKRI---NTMKSDIEKQKI-EIATLNQDVSDKNKTIQQLQNKLKNKE 860

Query: 1037 VSYMSM---VSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIK 1093
             S   +   ++D  S+++++    E   +E   ++ +L       E ++   +E++++ K
Sbjct: 861  NSVQRLNGEITDLRSRISEYEILNERQAKENALLNNKLKQKDVQIENIKEQPKEEEEKPK 920

Query: 1094 EL---------KETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKV 1144
            ++         KE+     +   ++ G +  S I    ++ NN              +K 
Sbjct: 921  QVGFAKPSLPPKESDQREFIKGSRSSGQLKFSPIATPPEENNNSLSQLEQFKKLNTTIKE 980

Query: 1145 QEEEEFIQERSV--LQEQSAKLNTELQECY--TKIIQLETLNTELTGHDVVNQEQINQLK 1200
            Q +    ++R +  L+++    N +L+E     +  ++     EL       + QI    
Sbjct: 981  QSQRLLAKDRKIDLLKQRLNDSNNQLKEIMETPENKRIAAKEKELEDFQQQLRSQIISQS 1040

Query: 1201 SKLEQLNTENDNLLSTVAE-LRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRV 1259
            S       E+D +     E  R  + +    +  EI  L K     +     K   E  +
Sbjct: 1041 SSFITYENESDAMKQIKEENYRRVVENT--HKDNEIIRLTKLLATDKTLKEDKILQEKIM 1098

Query: 1260 QLSAFESKYEQLLD-SVQSSTQEETNKIVT---MEQVTSLQNKLQDKEEHLRNLQEKYAD 1315
            QL   E+K +Q+ D + +++   E+  +      + + SL+ ++Q + +   N Q++  +
Sbjct: 1099 QL---EAKVQQMKDFNKETAANLESKNLENYNLQDNINSLKEQIQKQNDEQANHQKELDE 1155

Query: 1316 VINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEE-- 1373
               QI +L+ EIE  +  +                     N++  ++++  I+    E  
Sbjct: 1156 RDEQIAVLQKEIEKYENRYLEQQEVISQEKLNNSNLKLKLNEAENEIEKSHIVKQPGELY 1215

Query: 1374 NAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDE 1433
             +++ +               +  + AK+ EL  Q+E K+ +I     E T  L +++ E
Sbjct: 1216 LSEVPQQISYFENKVKIMNGMITQSNAKIKELESQIEKKNKQI-----ESTEALQKKSRE 1270

Query: 1434 FENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNV 1493
               + +Q+ +YE+R+  L    E ++  + + +   AN  +   K+ ++++ K I E   
Sbjct: 1271 ---LYRQIRDYEQRLSSLGLTVE-QIREMEMTIKNQANIIKA--KDDDLKQTKEILEYRE 1324

Query: 1494 KITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSK 1553
            +  E      +   +  A+E    + +E++  LE ++ E    ND+I  +Q   R +  +
Sbjct: 1325 EQIE--KFIAESVSIRDAIETLKQRISELEMLLEKKDKE---NNDKIAEIQEENRQTLEQ 1379

Query: 1554 IQKHVSFASD 1563
            + K +  A +
Sbjct: 1380 LAKQLQEAEE 1389



 Score =  114 bits (274), Expect = 2e-23
 Identities = 151/773 (19%), Positives = 351/773 (45%), Gaps = 60/773 (7%)

Query: 324  LTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKK-GSPLISRKSGRNTASKM 382
            L  KI++L      +   N   +N ++ + +  K VS   ++     I+  +      KM
Sbjct: 3524 LKGKIDILSR-EISMYSDNSSKDNLISKIVSLQKTVSEKDEQLNDAKINSNNSLEIEDKM 3582

Query: 383  KSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNK-DLVDKEYVISEKDTXXXXXXXX 441
            +    Q +S   + +   ++  N+ +      +S  K DL      +S  +         
Sbjct: 3583 QQEIDQKNSRIHHLENQMRVLLNKASHENAKEESKVKIDLKKANVKLSNLENDFSSLQEE 3642

Query: 442  XXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDL 501
                 + +++L+L  ++     +++    N  D+NEI++++ +L+++  D  ++   K  
Sbjct: 3643 NAALKSKVSKLELVIKEKQSEINIM-AQKNNNDINEISELKSKLRKQNEDFTQE---KSS 3698

Query: 502  IEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLT 561
             EK +S   +I QL +++ A N  +   KS  ++ LK         SK++   ++     
Sbjct: 3699 AEKQRS---EIDQLTNDLKAKNNELDDSKSEIRI-LK---------SKINQLQQDFDAKN 3745

Query: 562  EELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLES 621
              L   S+K+++LEE+    +L L++    + +++D   K I +E L    L+    L+ 
Sbjct: 3746 HSLQKESEKLSQLEEKMKEKELELLN----KSLDNDKAAKEI-IEKLQNENLEQSKQLKK 3800

Query: 622  QKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALV 681
            ++ D+ Q   IL    +E  +    I  LQ+D    +I     +E+        +EL  +
Sbjct: 3801 KEKDIEQMKQILNDLNNEQGELKGKIMTLQNDN--EQITKTS-QEKFKLNEKKSEELVSM 3857

Query: 682  IENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKIS------EL 735
            I  L  +  +   TI      KE  + KL+N ++++    +++  + +E +       +L
Sbjct: 3858 INKLNDEIAEKNKTINGTLLQKEKEITKLKNDLEQSQITNERITNLESEMMKMKQLNDDL 3917

Query: 736  LAKINHEEQSKIQTQFGIDA---KIQERDLYIENIESELSKYKSRICRLEESIAVMEDRR 792
            +  IN   +  I+ +  +     K+ +    ++ +  E S +  ++ ++ E   +++D+ 
Sbjct: 3918 MNDINRYNEELIEKENELQELREKLIQSGNNLQKVTPEQSYFDLQM-KITELEDIIKDKN 3976

Query: 793  YSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQ 852
              LE K +++ +      K Y+       +      + ++  R+   ++ E+E++NK+L 
Sbjct: 3977 SQLENKTNEITNLYS---KLYNTSPPSNSKKPRNTKLEVEKMRI---KMAELENKNKDLI 4030

Query: 853  KKN-------QILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLES 905
             +N       Q  + +N  L+  + D + ++N+ + + N          + +  + D   
Sbjct: 4031 DQNTRMNSDLQAQINQNNKLKRHMKDNENNFNSQINQLNLKLQKVVSDYEARLLILDNSK 4090

Query: 906  NLKRITHEHQTLIVQKKKEIEDLEIEFN-TQIES-AIRDKKVLNEKYEKNIE-YVTQLEA 962
            N  +  +E +  I QK +EI   E + N  ++E+  ++++  L++K  +++  Y++Q EA
Sbjct: 4091 NQTQRVNELRERIKQKNEEILSKEKQINENKLENDKLKNEIELSKKQNEDLSNYLSQKEA 4150

Query: 963  QLQEYKNNIENL---NMNVE-ELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALL 1018
            +++E +  I++L   N  +E ELNK ++   ++  +    +  D +EQ  N + + + L 
Sbjct: 4151 KIKELERRIQSLDEQNAKIEDELNK-SINKNEEINKSSIIERTDLSEQLNNALKENSRLK 4209

Query: 1019 KQKDEEIIALNQKIN-NAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQ 1070
             Q DE +  + +  + ++ ++ + +VSD    L+++   L++  EE++ +  Q
Sbjct: 4210 VQIDETVSKIKELCDKDSDIARVKLVSDQLIDLSEYCKLLKDQNEELKNMISQ 4262



 Score = 86.2 bits (204), Expect = 7e-15
 Identities = 181/929 (19%), Positives = 393/929 (42%), Gaps = 87/929 (9%)

Query: 696  IKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDA 755
            ++DL  +K    N   N   +N  + +  +++ A+ + +    I++ E        G D 
Sbjct: 16   VQDLRINKSQ--NSKMNESGQNSQIVED-DEVPAQLVDDSQLNISNIEAPNTNDTSGFDQ 72

Query: 756  KIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSE 815
            +++        + S  S+  ++  ++EESI + + R  S    + ++   L   +  +++
Sbjct: 73   RLKLSQGTRRTVRSA-SQILNQSPQIEESITLADSRDLSAIMSSKEIFDELNAIRNQFTD 131

Query: 816  ----YTIQEDELVNRLAVLMD-HDRVVEKQLL--EI-EHENKELQKKNQI---------L 858
                Y+    +L N +  L    + +  + ++  EI +++   L  +N I         L
Sbjct: 132  IDDFYSSDNQKLRNLVNALESLKNNLTNESIITHEISQNDGDTLISRNVINTNASFAAEL 191

Query: 859  LEENQNLQISLSDMQQHYNALVEKANRTDLAESEST----KYQTQLRDLESN--LKRITH 912
            L EN+ L +    + Q  N L  K  +    E++      KY+ +L +L +N  L  I  
Sbjct: 192  LNENEKLYLENRSLLQLKNELRAKNLKIIQIENDFRNRLRKYKHKLDELSNNEILDNILR 251

Query: 913  EH-QTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNI 971
            E  QT  + +    E   I  N ++  ++      N      ++   QL+ +L + +  I
Sbjct: 252  EKLQTRDMVQSVAQEQYAILHNFEVSKSLTRPNGNNSSNLHELDN-NQLQGELIKLREQI 310

Query: 972  ENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNAL-LKQKDEEIIALNQ 1030
              L+    E  +  LE +++  +  Q++ P   +Q ++++N L    + ++ + +  L  
Sbjct: 311  LELSKQKSE-TESKLEWVEQSNKLLQSK-PSENQQILDQLNTLRQKEIDEQQKHVEELTN 368

Query: 1031 KINNAQVSYMSMVSDYESKLAQFTT--KLENMEEEMQRVSKQLL---DSKQHNEELQILV 1085
            +   A+  Y   + D+  KL + +   + EN+ +E   +  QL     +K   E  +IL 
Sbjct: 369  QEKLAESEYQKQI-DHLKKLLESSNAAETENLRKENNNLRDQLAAIASNKNILENEEILT 427

Query: 1086 REQD--DQIKELKETKLTFEMNIPKTEGMIIS--STIEPMSDDANNVDXXXXXXXXXXXX 1141
               D  D++ ELK      +  I + E  I +  +TIE +  D   VD            
Sbjct: 428  SNFDLSDKVDELKSIIRNKDKQIIELESEIDNQKATIEDLKID---VDFKERTISDLENK 484

Query: 1142 LKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKS 1201
            + V    +  +   +L+E+  K  ++LQ+      Q+E  NT +      N+E+I+QL  
Sbjct: 485  INVSANPD--KGIELLKEEKDKAISKLQK------QIERQNTIIQQ----NEEKIDQLSK 532

Query: 1202 KLEQLNTENDNLL--STVAELRSSISSAVD---QRGFEIAELWKQHLAQREADFQKTEHE 1256
             +E  + + D ++  S  AE+ S   +A++   Q       +  + + Q++A  ++ E E
Sbjct: 533  DIEAKDQKIDEMIQKSLTAEVPSGDGAALELKLQNLNSYIAIQNEKMGQKDAKIEQLEDE 592

Query: 1257 LRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQN-KLQDKEEHLRNLQEKYAD 1315
             R +     S+    L  ++ +  E T KI  +E   +  N   ++ E +L  + ++ + 
Sbjct: 593  -RQKNDTKISELTSTLTQLKLTNNENTLKIAELENTIAKSNIPKKEGELYLSEVPQEVSF 651

Query: 1316 VINQIEILRS--EIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSY-KQMQE-QSILNIN 1371
            + N+  +L +  + + EK+                  ++  +++   +Q+Q+ ++ LN  
Sbjct: 652  LKNKNNMLNNINKSQAEKIKHLEQEIVKKNKQIGSIDEMHKKSRELQRQIQDYENKLNAQ 711

Query: 1372 EENAQLKKSSXXXXXXXXXXXXR--VNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQ 1429
            +  +  + S+               V D + + +EL   LE KD ++     +  +    
Sbjct: 712  QLESGGENSAELLSLKQQSNLLNQLVADLKKQNIELKKTLETKDKQLSSMMSDSLLV--- 768

Query: 1430 RNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLK-MHENANHYETMQKESEIERVKLI 1488
              D    +  +L    K I D  YE       LRL  +  + N +E + +E   +   + 
Sbjct: 769  -KDNLSEITAELASKNKIIHD--YE-------LRLNALSGSGNQFENLLQEKLTKIATME 818

Query: 1489 EELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMV- 1547
            + +N   ++      ++A LN+ + ++     ++Q  L+N+E  +  LN EIT+L++ + 
Sbjct: 819  KRINTMKSDIEKQKIEIATLNQDVSDKNKTIQQLQNKLKNKENSVQRLNGEITDLRSRIS 878

Query: 1548 --RASSSKIQKHVSFASDTKQGRDEQLDN 1574
                 + +  K  +  ++  + +D Q++N
Sbjct: 879  EYEILNERQAKENALLNNKLKQKDVQIEN 907



 Score = 51.6 bits (118), Expect = 2e-04
 Identities = 110/623 (17%), Positives = 251/623 (40%), Gaps = 33/623 (5%)

Query: 99   KQKEILMEKIKQYKELSKRSST-TIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNA 157
            KQ EI +   K   ++++ S   + +R               Q  ++  L+N +K K+N 
Sbjct: 3660 KQSEINIMAQKNNNDINEISELKSKLRKQNEDFTQEKSSAEKQRSEIDQLTNDLKAKNNE 3719

Query: 158  LSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQ 217
            L   + +++I+++ I  LQ+  + K+  ++ +++  +                  D  + 
Sbjct: 3720 LDDSKSEIRILKSKINQLQQDFDAKNHSLQKESEKLSQLEEKMKEKELELLNKSLDNDKA 3779

Query: 218  MTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQE 277
              ++ E       E   + ++  KDIE     ++ L      L+     +  ++ ++ + 
Sbjct: 3780 AKEIIEKLQNENLEQSKQLKKKEKDIEQMKQILNDLNNEQGELKGKIMTLQNDNEQITKT 3839

Query: 278  LEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTK-KIELLEHLNC 336
             ++              +  +  +   E+   I   G+L +    E+TK K +L +    
Sbjct: 3840 SQEKFKLNEKKSEELVSMINKLNDEIAEKNKTI--NGTL-LQKEKEITKLKNDLEQSQIT 3896

Query: 337  QIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSG-RNTASKMKSPWSQLSSETLN 395
              R TN E E  +         ++  ++    LI +++  +    K+    + L   T  
Sbjct: 3897 NERITNLESE-MMKMKQLNDDLMNDINRYNEELIEKENELQELREKLIQSGNNLQKVTPE 3955

Query: 396  QDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLE 455
            Q       + +I +LE +I+  N  L +K   I+   +           K     +L++E
Sbjct: 3956 QSYFDL--QMKITELEDIIKDKNSQLENKTNEITNLYSKLYNTSPPSNSKKPRNTKLEVE 4013

Query: 456  HQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQL 515
             +  ++   L     N + +++  ++   L+ ++N   K      L   +K  E      
Sbjct: 4014 -KMRIKMAEL--ENKNKDLIDQNTRMNSDLQAQINQNNK------LKRHMKDNE---NNF 4061

Query: 516  NDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELE 575
            N +I+  N  + KV S+++ +L  +  + +   +V++  + I +  EE+    +++ E +
Sbjct: 4062 NSQINQLNLKLQKVVSDYEARLLILDNSKNQTQRVNELRERIKQKNEEILSKEKQINENK 4121

Query: 576  EEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQ 635
             E   L+  +   +  +    D+   + + E   +   + I  L+ Q   +  EL+    
Sbjct: 4122 LENDKLKNEI---ELSKKQNEDLSNYLSQKEAKIKELERRIQSLDEQNAKIEDELNKSIN 4178

Query: 636  KYDEV-EDKLADISQLQSDQVCSEIK-SVHLEEQIDALSASKKELA---LVIENLKLDKE 690
            K +E+ +  + + + L S+Q+ + +K +  L+ QID   +  KEL      I  +KL  +
Sbjct: 4179 KNEEINKSSIIERTDL-SEQLNNALKENSRLKVQIDETVSKIKELCDKDSDIARVKLVSD 4237

Query: 691  QLYGT---IKDLENDKEDIMNKL 710
            QL       K L++  E++ N +
Sbjct: 4238 QLIDLSEYCKLLKDQNEELKNMI 4260


>UniRef50_UPI000049A29E Cluster: Viral A-type inclusion protein
            repeat; n=2; Entamoeba histolytica HM-1:IMSS|Rep: Viral
            A-type inclusion protein repeat - Entamoeba histolytica
            HM-1:IMSS
          Length = 1813

 Score =  214 bits (522), Expect = 2e-53
 Identities = 312/1490 (20%), Positives = 644/1490 (43%), Gaps = 145/1490 (9%)

Query: 143  DVTHLSNTIKEKDNALS-VLQVKMKIME--TTILDLQEKI-NEKDQII---EAKNKATTX 195
            ++T L     +K+N L+ V   K +++E   T  +  EKI NE  Q+    E K      
Sbjct: 276  ELTQLKTDNDQKENELNQVRHEKDEVIEKFNTSKEENEKIMNELSQLKQEKEEKENELKE 335

Query: 196  XXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEE 255
                             +    ++K+ E     + E K+E    L  I+ +  RI   EE
Sbjct: 336  QVKKMEEEKSKLITELSNGSDGISKLNEELTQTKQE-KEEINNELNSIKEEKKRIE--EE 392

Query: 256  ANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGS 315
             N+++   + EI  E  K+ +E ++              L  + I        EIEEK  
Sbjct: 393  KNQIINENK-EIKEEKEKIEEEKKELLKEIEKEKEGNNQLQNE-INTIQTRMKEIEEKNQ 450

Query: 316  LEIA-NMTELTKKIELLEHLNCQIRQTNKELE------NKLATMGTESKAVSSPSKKGSP 368
              I  N  E+ K  E  E+L  ++ Q  +E +      N+L  + T+ +   +  K+   
Sbjct: 451  EIICDNNKEIAKFKEEQENLQKELNQIKEEKQKTENEKNELVDVKTQKENELNKLKEEKE 510

Query: 369  LI--SRKSGRNTASKMKSPWSQLSSE--TLNQDTDKKINKNEIAKLEMVIQSLNKDLVDK 424
             I   + +  N+ +++    ++L+ E  ++ Q+ D     N   +LE+   +  K+ +  
Sbjct: 511  QIFNEKTTIENSLNQIVEEKNKLTEEKESIKQELDSIKADNSTKELEINKINEEKNQLQN 570

Query: 425  EY--VISEKDTXXXXXXXXXXGKDTLIAQLQL--EHQQHMEGPS---LIHVGTNTEDVNE 477
            +Y  V  EK+            K     +L    E +Q +E      +  +    + + +
Sbjct: 571  DYDTVQQEKENIQKELNQIKIEKSQKEEELNKIKEEKQQVEDEKAKLITDIANGNDGLTK 630

Query: 478  IAKVQEQLKQE---LNDEIKDV-NVKDLIE-KLKSAEEQITQLNDEIDAANKNMIKVKSN 532
            + +V ++LK E   +++E+  + N +D I  +    +E+I Q  +E    N+    V  N
Sbjct: 631  LNEVIDKLKDEKENISNELNQIKNERDNISNEFNKTKEEIKQKENETIQLNEEK-SVLLN 689

Query: 533  HKLKLKQMQKTIDNFSKVSDSNKE--IVRLTEELHHLSQKVAELEEEKGNLQLHLVDY-D 589
               ++K+ ++ I++   V    KE  I +L E+   +  ++ +++ EK  ++  L    D
Sbjct: 690  ELNQIKEEKQKIEDEKAVIQQEKENEITKLNEDKTVIENELNQIKTEKQEIENELNQTKD 749

Query: 590  SGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQ 649
              + IE +  K + E+ N  +     IS L  +     QE   +  + ++++++ A   +
Sbjct: 750  EKQKIEDEKSKLITELSNGND----GISKLNEELTQTKQEKENVLNELNQIKNEFASFKE 805

Query: 650  LQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNK 709
             Q+ Q  +E+K  + + Q + L     E++ + E       +L  T ++LE  K++I+  
Sbjct: 806  -QNTQKENELKDENNKVQQE-LEQKNNEVSKLEEEKGNISNELSNTKQELEQKKQEIITI 863

Query: 710  LQNYIQENMDLTDKLEKMSAEK---ISEL------LAKINHEEQSKIQTQFGIDAKIQER 760
             Q   ++  +L ++++K+  EK   I+EL      ++K+N E     Q +  I   ++E 
Sbjct: 864  TQEKEEKENELKEQVKKIEEEKSKLITELSNGSDGISKLNEELTQTKQEKEEIQKALEEE 923

Query: 761  DLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTI-- 818
               +E IE+EL + K     LEE      ++  ++E K + L   L E +K   E T   
Sbjct: 924  KEKLERIETELKEIKEAKQELEE------EKNKTIEEKTN-LQQELNENKKIVEELTQTK 976

Query: 819  -QEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEEN-QNLQISLSDMQQHY 876
             +++E+ N L  + +  + +E++  +I +ENKE++++N   +EE  Q +    + +++  
Sbjct: 977  QEKEEINNELNSIKEEKKRIEEEKNQIINENKEIKEENIKSIEEKTQEINSLTTSIEELK 1036

Query: 877  NALVEKANRTDLAESESTKYQTQLRDLE---SNLKRITHEHQTLIVQKKKEIEDLEIEFN 933
              L E        E E  +  ++L D++     +K+   E    + + +K  E  E E  
Sbjct: 1037 GRLEESKGERIEIEKERDRVISELNDIKLQNEGMKKQVEEAHNRMTEMQKSFEGSENEMI 1096

Query: 934  TQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHV 993
              + + I     LNEK ++  E V  L+ QL +        N+N+EE+ K  +E  +K+ 
Sbjct: 1097 NSLNNQITQ---LNEKEKQMNEQVMALQTQLSQS-------NINLEEVKKDLIESQNKYT 1146

Query: 994  QKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQF 1053
            Q  + +  D  EQ   E NK+N   K  +EE+    +++N+ Q  Y + + +      + 
Sbjct: 1147 QINEEK--DCVEQ---ERNKINEEYKTVNEELEKNKKELNDLQTKYDNEILELNKNKDEL 1201

Query: 1054 TTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMI 1113
             + + N++EE   + +Q+   ++   +L   +    D + +L E     E+   K E   
Sbjct: 1202 NSLINNLKEEKTNLEEQVKKMEEEKSKLITELSNGSDGVSKLNE-----ELTQTKQEKEE 1256

Query: 1114 ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQE--QSAKLNTELQEC 1171
            I++ +  + ++   ++            +K ++E+   +++ +L+E  +  + N +LQ  
Sbjct: 1257 INNELNSIKEEKKRIEEEKNQIINENKEIKEEKEKIEEEKKELLKEIEKEKEGNNQLQN- 1315

Query: 1172 YTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQR 1231
                 ++ T+ T +   +  NQE I     ++ +   E +NL   + +++   S  +   
Sbjct: 1316 -----EINTIQTRMKEIEEKNQEIICDNNKEIAKFKEEQENLQKELNQIKEEKSKLITDL 1370

Query: 1232 GFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQ 1291
                  L K  L +      K +  +R +L + + +  ++ D ++   QE  +K+   E+
Sbjct: 1371 SNGNDGLSK--LNEEIETINKEKEGIRKELESLKEENNKIQDELEQKNQE-LSKV--KEE 1425

Query: 1292 VTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXD 1351
               L + L +  + +  L E     +NQI+  + E+ ++ V                  +
Sbjct: 1426 KEKLIHDLTNGNDGINQLNED----LNQIKNDKEELTEKNVQLQNEINKLKSENEELSNN 1481

Query: 1352 LRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLEL 1411
            L  E +  KQ+ E+ +  I EE  +L K              ++ + + KV E   +L  
Sbjct: 1482 LSFEKEGLKQVNEE-VNAIKEERDELVKQ-----------IKKIEEEKRKVEE---ELNF 1526

Query: 1412 KDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENAN 1471
              SE+ ++  +      Q N E   ++Q L E + +IE++  EKES              
Sbjct: 1527 NGSEVNEQIAQINNEKEQLNQECNELKQNLKELQSKIEEIEQEKES-------------- 1572

Query: 1472 HYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEI 1531
                    +EI++ + ++EL  +ITE  +  K + E  + +E+E+ +  E    + N   
Sbjct: 1573 --------NEIKKKEELQELQEEITEKDNDIKNLKEEIERIEKELQEKEEDMEQMSNNTE 1624

Query: 1532 EIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQG---RDEQLDNTMNK 1578
            E+  L +++T  Q ++     + +   +   +TK+      ++++N MNK
Sbjct: 1625 ELEELKNKLTETQRLLEEEKKEKESISNEFEETKEQVLVELQRVNNEMNK 1674



 Score =  202 bits (492), Expect = 8e-50
 Identities = 259/1300 (19%), Positives = 576/1300 (44%), Gaps = 111/1300 (8%)

Query: 319  ANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSS--PSKKGSPLISRKSGR 376
            +++   T   E+   +N QI + NK L+N+   +  +  A  S   +K  S + ++K   
Sbjct: 163  SSLASETTAEEVNRSVNAQIEEENKRLQNENEELKKKCDAQDSLLKTKMKSEMEAKKKVE 222

Query: 377  NTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXX 436
               ++ K    ++++E    D   K+N+ E+ +++   +S+N +L+  +    EK++   
Sbjct: 223  ILENEKKDLIDKMANEN---DGMSKLNE-ELTQIKNEKESINNELIQTK---QEKESINN 275

Query: 437  XXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDV 496
                     D    + +L   +H +   +    T+ E+  +I     QLKQE     K+ 
Sbjct: 276  ELTQLKTDNDQ--KENELNQVRHEKDEVIEKFNTSKEENEKIMNELSQLKQE-----KEE 328

Query: 497  NVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKL-KLKQMQKTIDNFSKVSDSNK 555
               +L E++K  EE+ ++L  E+   +  + K+  N +L + KQ ++ I+N  +++   +
Sbjct: 329  KENELKEQVKKMEEEKSKLITELSNGSDGISKL--NEELTQTKQEKEEINN--ELNSIKE 384

Query: 556  EIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKA 615
            E  R+ EE + +  +  E++EEK  ++    +       E +   ++    N  +TR+K 
Sbjct: 385  EKKRIEEEKNQIINENKEIKEEKEKIEEEKKELLKEIEKEKEGNNQLQNEINTIQTRMKE 444

Query: 616  ISLLESQKFDLVQELHILQQKYDEVEDKLA-DISQLQSDQVCSEIKSVHLEEQIDALSAS 674
            I   E +  +++ + +    K+ E ++ L  +++Q++ ++  +E +     E +D  +  
Sbjct: 445  I---EEKNQEIICDNNKEIAKFKEEQENLQKELNQIKEEKQKTENEK---NELVDVKTQK 498

Query: 675  KKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISE 734
            + EL      LK +KEQ++     +EN    I+ +     +E   +  +L+ + A+  ++
Sbjct: 499  ENEL----NKLKEEKEQIFNEKTTIENSLNQIVEEKNKLTEEKESIKQELDSIKADNSTK 554

Query: 735  LLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYS 794
             L +IN   + K Q Q   D   QE+    ENI+ EL++ K    + EE +  +++ +  
Sbjct: 555  EL-EINKINEEKNQLQNDYDTVQQEK----ENIQKELNQIKIEKSQKEEELNKIKEEKQQ 609

Query: 795  LERKADQL-------GSYLQEKQKAYSEYTIQEDELVNRL-AVLMDHDRV------VEKQ 840
            +E +  +L          L +  +   +   +++ + N L  +  + D +       +++
Sbjct: 610  VEDEKAKLITDIANGNDGLTKLNEVIDKLKDEKENISNELNQIKNERDNISNEFNKTKEE 669

Query: 841  LLEIEHENKELQKKNQILL-------EENQNLQISLSDMQQHYNALVEKANRTD-LAESE 892
            + + E+E  +L ++  +LL       EE Q ++   + +QQ     + K N    + E+E
Sbjct: 670  IKQKENETIQLNEEKSVLLNELNQIKEEKQKIEDEKAVIQQEKENEITKLNEDKTVIENE 729

Query: 893  STKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEK 952
              + +T+ +++E+ L +   E Q +  +K K I +L    N  I     +     ++ E 
Sbjct: 730  LNQIKTEKQEIENELNQTKDEKQKIEDEKSKLITELS-NGNDGISKLNEELTQTKQEKEN 788

Query: 953  NIEYVTQLEAQLQEYKN-NIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEI 1011
             +  + Q++ +   +K  N +  N   +E NK+  EL  K+ +  + +  +      NE+
Sbjct: 789  VLNELNQIKNEFASFKEQNTQKENELKDENNKVQQELEQKNNEVSKLE--EEKGNISNEL 846

Query: 1012 NKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQL 1071
            +     L+QK +EII + Q+    +      V   E + ++  T+L N  + + +++++L
Sbjct: 847  SNTKQELEQKKQEIITITQEKEEKENELKEQVKKIEEEKSKLITELSNGSDGISKLNEEL 906

Query: 1072 LDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXX 1131
              +KQ  EE+Q  + E+ ++++ + ET+L  E+   K E   +        ++  N+   
Sbjct: 907  TQTKQEKEEIQKALEEEKEKLERI-ETELK-EIKEAKQE---LEEEKNKTIEEKTNLQQ- 960

Query: 1132 XXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHD-V 1190
                       ++ E ++ ++E +  +++  ++N EL     +  ++E    ++   +  
Sbjct: 961  -----------ELNENKKIVEELTQTKQEKEEINNELNSIKEEKKRIEEEKNQIINENKE 1009

Query: 1191 VNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADF 1250
            + +E I  ++ K +++N    +L +++ EL+  +  +  +R  EI E  +  +     D 
Sbjct: 1010 IKEENIKSIEEKTQEIN----SLTTSIEELKGRLEESKGER-IEI-EKERDRVISELNDI 1063

Query: 1251 QKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQ 1310
            +     ++ Q+    ++  ++  S + S  E  N +    Q+T L  K +   E +  LQ
Sbjct: 1064 KLQNEGMKKQVEEAHNRMTEMQKSFEGSENEMINSL--NNQITQLNEKEKQMNEQVMALQ 1121

Query: 1311 EKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNI 1370
             +    ++Q  I   E++ + +                  +    N+ YK + E+   N 
Sbjct: 1122 TQ----LSQSNINLEEVKKDLIESQNKYTQINEEKDCVEQERNKINEEYKTVNEELEKNK 1177

Query: 1371 NEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQR 1430
             E N  L+                +N     + E    LE +  ++ ++  +    L+  
Sbjct: 1178 KELN-DLQTKYDNEILELNKNKDELNSLINNLKEEKTNLEEQVKKMEEEKSKLITELSNG 1236

Query: 1431 NDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEE 1490
            +D    + ++L + ++  E++  E  S +   + ++ E  N      KE + E+ K IEE
Sbjct: 1237 SDGVSKLNEELTQTKQEKEEINNELNS-IKEEKKRIEEEKNQIINENKEIKEEKEK-IEE 1294

Query: 1491 LNVKITESVSLNKQVAELNKALEEEV--AKTNEMQTALENQEI------EIVTLNDEITN 1542
               ++ + +   K   E N  L+ E+   +T   +   +NQEI      EI    +E  N
Sbjct: 1295 EKKELLKEIEKEK---EGNNQLQNEINTIQTRMKEIEEKNQEIICDNNKEIAKFKEEQEN 1351

Query: 1543 LQ---NMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKE 1579
            LQ   N ++   SK+   +S  +D     +E+++ T+NKE
Sbjct: 1352 LQKELNQIKEEKSKLITDLSNGNDGLSKLNEEIE-TINKE 1390



 Score =  190 bits (464), Expect = 2e-46
 Identities = 301/1493 (20%), Positives = 639/1493 (42%), Gaps = 132/1493 (8%)

Query: 151  IKEKDNALSVLQVKMKIMETTILDLQEKI-NEKDQIIEAKNKATTXXXXXXXXXXXXXXX 209
            +K K  +    + K++I+E    DL +K+ NE D + +   + T                
Sbjct: 207  LKTKMKSEMEAKKKVEILENEKKDLIDKMANENDGMSKLNEELTQIKNEKESINNELI-- 264

Query: 210  XXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDI--ESKDV--RISSLEEANKLLEAARF 265
                TKQ+   +      ++ +  D+K+  L  +  E  +V  + ++ +E N+ +     
Sbjct: 265  ---QTKQEKESINNELTQLKTD-NDQKENELNQVRHEKDEVIEKFNTSKEENEKIMNELS 320

Query: 266  EISLEHSKLAQEL-EQXXXXXXXXXXXXXXLAKQS--IEPSCEEKTEI-EEKGSL--EIA 319
            ++  E  +   EL EQ              L+  S  I    EE T+  +EK  +  E+ 
Sbjct: 321  QLKQEKEEKENELKEQVKKMEEEKSKLITELSNGSDGISKLNEELTQTKQEKEEINNELN 380

Query: 320  NMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTA 379
            ++ E  K+IE  E  N QI   NKE++ +   +  E K +    +K          +N  
Sbjct: 381  SIKEEKKRIE--EEKN-QIINENKEIKEEKEKIEEEKKELLKEIEKEKE--GNNQLQNEI 435

Query: 380  SKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXX 439
            + +++   ++  E  NQ+     NK EIAK +   ++L K+L   +    + +       
Sbjct: 436  NTIQTRMKEI--EEKNQEIICDNNK-EIAKFKEEQENLQKELNQIKEEKQKTENEKNELV 492

Query: 440  XXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTN--TEDVNEIAKVQEQLKQELNDEIKDVN 497
                 K+  + +L+ E +Q     + I    N   E+ N++ + +E +KQEL+    D +
Sbjct: 493  DVKTQKENELNKLKEEKEQIFNEKTTIENSLNQIVEEKNKLTEEKESIKQELDSIKADNS 552

Query: 498  VKDL-IEKLKSAEEQITQLNDEIDAANKNMIK----VKSNHKLKLKQMQKTIDNFSKVSD 552
             K+L I K+   + Q+    D +    +N+ K    +K     K +++ K  +   +V D
Sbjct: 553  TKELEINKINEEKNQLQNDYDTVQQEKENIQKELNQIKIEKSQKEEELNKIKEEKQQVED 612

Query: 553  SNKEIV----RLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENL 608
               +++       + L  L++ + +L++EK N+   L    + R   S+ + K    E +
Sbjct: 613  EKAKLITDIANGNDGLTKLNEVIDKLKDEKENISNELNQIKNERDNISNEFNKT--KEEI 670

Query: 609  AETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVC--SEIKSVHLEE 666
             +   + I L E +K  L+ EL+ ++++  ++ED+ A I Q + +++   +E K+V +E 
Sbjct: 671  KQKENETIQLNE-EKSVLLNELNQIKEEKQKIEDEKAVIQQEKENEITKLNEDKTV-IEN 728

Query: 667  QIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEK 726
            +++ +   K+E+   +   K +K+++       E++K  ++ +L N       L ++L +
Sbjct: 729  ELNQIKTEKQEIENELNQTKDEKQKI-------EDEKSKLITELSNGNDGISKLNEELTQ 781

Query: 727  MSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIEN--IESELSKYKSRICRLEES 784
               EK   +L ++N  +       F      +E +L  EN  ++ EL +  + + +LEE 
Sbjct: 782  TKQEK-ENVLNELNQIKNEF--ASFKEQNTQKENELKDENNKVQQELEQKNNEVSKLEEE 838

Query: 785  IA----VMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQ----EDE---LVNRLAVLMDH 833
                   + + +  LE+K  ++ +  QEK++  +E   Q    E+E   L+  L+   D 
Sbjct: 839  KGNISNELSNTKQELEQKKQEIITITQEKEEKENELKEQVKKIEEEKSKLITELSNGSDG 898

Query: 834  DRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESES 893
               + ++L + + E +E+QK  +   E+ + ++  L ++++    L E+ N+T     E 
Sbjct: 899  ISKLNEELTQTKQEKEEIQKALEEEKEKLERIETELKEIKEAKQELEEEKNKTI---EEK 955

Query: 894  TKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKN 953
            T  Q +L +     K+I  E    + Q K+E E++  E N+  E   R ++  N+   +N
Sbjct: 956  TNLQQELNEN----KKIVEE----LTQTKQEKEEINNELNSIKEEKKRIEEEKNQIINEN 1007

Query: 954  IEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINK 1013
             E   +    ++E    I +L  ++EEL     E   + ++ ++ +    +E  +N+I  
Sbjct: 1008 KEIKEENIKSIEEKTQEINSLTTSIEELKGRLEESKGERIEIEKERDRVISE--LNDIKL 1065

Query: 1014 LN-ALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLL 1072
             N  + KQ +E    + +   + + S   M++   +++ Q   K + M E++  +  QL 
Sbjct: 1066 QNEGMKKQVEEAHNRMTEMQKSFEGSENEMINSLNNQITQLNEKEKQMNEQVMALQTQLS 1125

Query: 1073 DSKQHNEELQILVREQDDQIKELKETK--LTFEMNIPKTEGMIISSTIEPMSDDANNVDX 1130
             S  + EE++  + E  ++  ++ E K  +  E N    E   ++  +E    + N++  
Sbjct: 1126 QSNINLEEVKKDLIESQNKYTQINEEKDCVEQERNKINEEYKTVNEELEKNKKELNDLQT 1185

Query: 1131 XXXXXXXXXXXLKVQEEE---EFIQERSVLQEQSAKLNTELQECYTKIIQ----LETLNT 1183
                        K +         +E++ L+EQ  K+  E  +  T++      +  LN 
Sbjct: 1186 KYDNEILELNKNKDELNSLINNLKEEKTNLEEQVKKMEEEKSKLITELSNGSDGVSKLNE 1245

Query: 1184 ELTGHDVVNQE---QINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWK 1240
            ELT      +E   ++N +K + +++  E + +++   E++       +++   + E+ K
Sbjct: 1246 ELTQTKQEKEEINNELNSIKEEKKRIEEEKNQIINENKEIKEEKEKIEEEKKELLKEIEK 1305

Query: 1241 QHLAQREADFQKTEHELRVQLSAFESKYEQLL----------DSVQSSTQEETNKIVTME 1290
            +     +   Q   + ++ ++   E K ++++             Q + Q+E N+I   E
Sbjct: 1306 EKEGNNQ--LQNEINTIQTRMKEIEEKNQEIICDNNKEIAKFKEEQENLQKELNQI--KE 1361

Query: 1291 QVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXX 1350
            + + L   L +  + L  L E+   +  + E +R E+E  K                   
Sbjct: 1362 EKSKLITDLSNGNDGLSKLNEEIETINKEKEGIRKELESLKEENNKIQDELEQKNQELSK 1421

Query: 1351 DLRTENQSYKQMQE--QSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQ 1408
                + +    +      I  +NE+  Q+K                +N  +++  EL++ 
Sbjct: 1422 VKEEKEKLIHDLTNGNDGINQLNEDLNQIKNDKEELTEKNVQLQNEINKLKSENEELSNN 1481

Query: 1409 LELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHE 1468
            L  +   + Q   E         +  +  R +LV+  K+IE+   + E EL         
Sbjct: 1482 LSFEKEGLKQVNEEV--------NAIKEERDELVKQIKKIEEEKRKVEEEL--------- 1524

Query: 1469 NANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALEN 1528
            N N  E  ++ ++I   K  E+LN +  E   L + + EL   +EE + +  E     + 
Sbjct: 1525 NFNGSEVNEQIAQINNEK--EQLNQECNE---LKQNLKELQSKIEE-IEQEKESNEIKKK 1578

Query: 1529 QEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELL 1581
            +E++   L +EIT   N ++    +I++      + ++  ++  +NT   E L
Sbjct: 1579 EELQ--ELQEEITEKDNDIKNLKEEIERIEKELQEKEEDMEQMSNNTEELEEL 1629



 Score =  173 bits (422), Expect = 3e-41
 Identities = 258/1282 (20%), Positives = 566/1282 (44%), Gaps = 119/1282 (9%)

Query: 149  NTIKEKDNALSVLQVKMKI-METTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXX 207
            N I E+ N L+  +  +K  +++   D   K  E ++I E KN+                
Sbjct: 524  NQIVEEKNKLTEEKESIKQELDSIKADNSTKELEINKINEEKNQLQNDYDTVQQEKENIQ 583

Query: 208  XXXXEDTKQQMTKMQE-NFIAMEAEW-KDEKQRLLKDIESKDVRISSLEEANKLLEAARF 265
                +   ++  K +E N I  E +  +DEK +L+ DI + +  ++ L E    L+  + 
Sbjct: 584  KELNQIKIEKSQKEEELNKIKEEKQQVEDEKAKLITDIANGNDGLTKLNEVIDKLKDEKE 643

Query: 266  EISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELT 325
             IS E +++  E +                 K+ I+    E  ++ E+ S+ +  + ++ 
Sbjct: 644  NISNELNQIKNERDNISNEFNKT--------KEEIKQKENETIQLNEEKSVLLNELNQIK 695

Query: 326  KKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSP 385
            ++ + +E     I+Q   E EN++  +  +   + +   +      ++   N  ++ K  
Sbjct: 696  EEKQKIEDEKAVIQQ---EKENEITKLNEDKTVIENELNQIKT--EKQEIENELNQTKDE 750

Query: 386  WSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGK 445
              ++  E     T+     + I+KL    + L +   +KE V++E +             
Sbjct: 751  KQKIEDEKSKLITELSNGNDGISKLN---EELTQTKQEKENVLNELNQIKNEFASFKEQN 807

Query: 446  DTLIAQLQLEH---QQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLI 502
                 +L+ E+   QQ +E  +           NE++K++E+ K  +++E+   N K  +
Sbjct: 808  TQKENELKDENNKVQQELEQKN-----------NEVSKLEEE-KGNISNELS--NTKQEL 853

Query: 503  EKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKL-KQMQKTIDNFSKVSDSNKEIVRLT 561
            E+ K     ITQ  +E +   K  +K     K KL  ++    D  SK+   N+E+ +  
Sbjct: 854  EQKKQEIITITQEKEEKENELKEQVKKIEEEKSKLITELSNGSDGISKL---NEELTQTK 910

Query: 562  EELHHLSQKVAELEEEKGNLQLHLVDYDSGRM-IESDVYKKMIEMENLAETRLKAISLLE 620
            +E   + + + E +E+   ++  L +    +  +E +  K + E  NL +       L E
Sbjct: 911  QEKEEIQKALEEEKEKLERIETELKEIKEAKQELEEEKNKTIEEKTNLQQ------ELNE 964

Query: 621  SQKFDLVQELHILQQKYDEVEDKLADISQL------QSDQVCSEIKSVHLEEQIDALSAS 674
            ++K  +V+EL   +Q+ +E+ ++L  I +       + +Q+ +E K +  EE I ++   
Sbjct: 965  NKK--IVEELTQTKQEKEEINNELNSIKEEKKRIEEEKNQIINENKEIK-EENIKSIEEK 1021

Query: 675  KKE---LALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEK 731
             +E   L   IE LK   E+  G   ++E +++ ++++L +   +N  +  ++E+ +  +
Sbjct: 1022 TQEINSLTTSIEELKGRLEESKGERIEIEKERDRVISELNDIKLQNEGMKKQVEE-AHNR 1080

Query: 732  ISELLAKINHEEQSKIQTQFGIDAKIQERDLYIEN----IESELSKYKSRICRLEESIAV 787
            ++E+       E   I +      ++ E++  +      ++++LS+    +  +++ +  
Sbjct: 1081 MTEMQKSFEGSENEMINSLNNQITQLNEKEKQMNEQVMALQTQLSQSNINLEEVKKDLIE 1140

Query: 788  MEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHE 847
             +++   +  + D +    QE+ K   EY    +EL      L D     + ++LE+   
Sbjct: 1141 SQNKYTQINEEKDCVE---QERNKINEEYKTVNEELEKNKKELNDLQTKYDNEILELNKN 1197

Query: 848  NKELQKKNQILLEENQNLQISLSDMQQHYNALV-EKANRTD---LAESESTKYQTQLRDL 903
              EL      L EE  NL+  +  M++  + L+ E +N +D       E T+ + +  ++
Sbjct: 1198 KDELNSLINNLKEEKTNLEEQVKKMEEEKSKLITELSNGSDGVSKLNEELTQTKQEKEEI 1257

Query: 904  ESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQ 963
             + L  I  E +  I ++K +I +   E   + E    +KK L ++ EK  E   QL+ +
Sbjct: 1258 NNELNSIKEEKKR-IEEEKNQIINENKEIKEEKEKIEEEKKELLKEIEKEKEGNNQLQNE 1316

Query: 964  LQEYKNNIENLNMNVEELNKMNLELIDK------HVQKQQTQSPDYTEQYINEINKLNAL 1017
            +   +  ++ +    +E+   N + I K      ++QK+  Q  +   + I +++  N  
Sbjct: 1317 INTIQTRMKEIEEKNQEIICDNNKEIAKFKEEQENLQKELNQIKEEKSKLITDLSNGNDG 1376

Query: 1018 LKQKDEEIIALNQKINNAQVSYMSMVSD---YESKLAQFTTKLENMEEEMQRVSKQLLDS 1074
            L + +EEI  +N++    +    S+  +    + +L Q   +L  ++EE +++   L + 
Sbjct: 1377 LSKLNEEIETINKEKEGIRKELESLKEENNKIQDELEQKNQELSKVKEEKEKLIHDLTNG 1436

Query: 1075 K----QHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDX 1130
                 Q NE+L   ++   +++ E K  +L  E+N  K+E   +S+ +    +    V+ 
Sbjct: 1437 NDGINQLNEDLN-QIKNDKEELTE-KNVQLQNEINKLKSENEELSNNLSFEKEGLKQVNE 1494

Query: 1131 XXXXXXXXXXXL-----KVQEEEEFIQER-----SVLQEQSAKLNTELQECYTKIIQLET 1180
                       L     K++EE+  ++E      S + EQ A++N E ++   +  +L+ 
Sbjct: 1495 EVNAIKEERDELVKQIKKIEEEKRKVEEELNFNGSEVNEQIAQINNEKEQLNQECNELKQ 1554

Query: 1181 LNTELTG--HDVVNQEQINQLKSK--LEQLN---TENDNLLSTVAELRSSISSAVDQRGF 1233
               EL     ++  +++ N++K K  L++L    TE DN +  + E    I   + ++  
Sbjct: 1555 NLKELQSKIEEIEQEKESNEIKKKEELQELQEEITEKDNDIKNLKEEIERIEKELQEKEE 1614

Query: 1234 EIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVT 1293
            ++ ++        E   + TE +   +L   E K ++ + +    T+E+   +V +++V 
Sbjct: 1615 DMEQMSNNTEELEELKNKLTETQ---RLLEEEKKEKESISNEFEETKEQV--LVELQRVN 1669

Query: 1294 SLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLR 1353
            +  NK+ + ++   N +E+  + IN+   L+S+IE E                    +L+
Sbjct: 1670 NEMNKMNEIKQEDENEKEELQEHINK---LKSQIERENEQLKEVSKLKWELS-----ELK 1721

Query: 1354 TENQSYKQ--MQEQSILNINEE 1373
            TEN+S KQ  M ++S+L+  ++
Sbjct: 1722 TENESMKQMIMNKKSLLDNTDD 1743



 Score =  172 bits (418), Expect = 8e-41
 Identities = 220/1029 (21%), Positives = 454/1029 (44%), Gaps = 96/1029 (9%)

Query: 215  KQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKL 274
            K +    +E     E E KDE  ++ +++E K+  +S LEE        +  IS E S  
Sbjct: 797  KNEFASFKEQNTQKENELKDENNKVQQELEQKNNEVSKLEEE-------KGNISNELSNT 849

Query: 275  AQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTE-IEEKGSLEIANMTELTKKIELLEH 333
             QELEQ                K+  E   +E+ + IEE+ S  I   TEL+   + +  
Sbjct: 850  KQELEQKKQEIITITQE-----KEEKENELKEQVKKIEEEKSKLI---TELSNGSDGISK 901

Query: 334  LNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSET 393
            LN ++ QT +E E          KA+    +K   +           ++K    +L  E 
Sbjct: 902  LNEELTQTKQEKEEI-------QKALEEEKEKLERI------ETELKEIKEAKQELEEEK 948

Query: 394  LNQDTDKKIN-KNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQL 452
             N+  ++K N + E+ + + +++ L +   +KE + +E ++           K+ +I + 
Sbjct: 949  -NKTIEEKTNLQQELNENKKIVEELTQTKQEKEEINNELNSIKEEKKRIEEEKNQIINE- 1006

Query: 453  QLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQI 512
                 + ++  ++  +   T+++N +    E+LK  L +E K     + IE  K  +  I
Sbjct: 1007 ----NKEIKEENIKSIEEKTQEINSLTTSIEELKGRL-EESKG----ERIEIEKERDRVI 1057

Query: 513  TQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSK--VSDSNKEIVRLTEELHHLSQK 570
            ++LND I   N+ M K       ++ +MQK+ +      ++  N +I +L E+   ++++
Sbjct: 1058 SELND-IKLQNEGMKKQVEEAHNRMTEMQKSFEGSENEMINSLNNQITQLNEKEKQMNEQ 1116

Query: 571  VAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAIS----LLESQKFDL 626
            V  L+ +     ++L +     +   + Y ++ E ++  E     I+     +  +    
Sbjct: 1117 VMALQTQLSQSNINLEEVKKDLIESQNKYTQINEEKDCVEQERNKINEEYKTVNEELEKN 1176

Query: 627  VQELHILQQKYD-EVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIEN- 684
             +EL+ LQ KYD E+ +   +  +L S     + +  +LEEQ+  +   K +L   + N 
Sbjct: 1177 KKELNDLQTKYDNEILELNKNKDELNSLINNLKEEKTNLEEQVKKMEEEKSKLITELSNG 1236

Query: 685  -------------LKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEK 731
                          K +KE++   +  ++ +K+ I  +    I EN ++ ++ EK+  EK
Sbjct: 1237 SDGVSKLNEELTQTKQEKEEINNELNSIKEEKKRIEEEKNQIINENKEIKEEKEKIEEEK 1296

Query: 732  ISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDR 791
              ELL +I  E++   Q Q  I+  IQ R   IE    E+      IC   + IA  ++ 
Sbjct: 1297 -KELLKEIEKEKEGNNQLQNEINT-IQTRMKEIEEKNQEI------ICDNNKEIAKFKEE 1348

Query: 792  RYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKEL 851
            + +L+++ +Q+    +EK K  ++ +   D L    + L +    + K+   I  E + L
Sbjct: 1349 QENLQKELNQIK---EEKSKLITDLSNGNDGL----SKLNEEIETINKEKEGIRKELESL 1401

Query: 852  QKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRIT 911
            +++N  + +E +     LS +++    L+      +   ++  +   Q+++ +  L    
Sbjct: 1402 KEENNKIQDELEQKNQELSKVKEEKEKLIHDLTNGNDGINQLNEDLNQIKNDKEELTEKN 1461

Query: 912  HEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNI 971
             + Q  I + K E E+L    + + E   +  + +N   E+  E V Q++ +++E K  +
Sbjct: 1462 VQLQNEINKLKSENEELSNNLSFEKEGLKQVNEEVNAIKEERDELVKQIK-KIEEEKRKV 1520

Query: 972  ENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQK 1031
            E      EELN    E     V +Q  Q  +  EQ   E N+L   LK+   +I  + Q+
Sbjct: 1521 E------EELNFNGSE-----VNEQIAQINNEKEQLNQECNELKQNLKELQSKIEEIEQE 1569

Query: 1032 INNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQ 1091
              + ++     + + + ++ +    ++N++EE++R+ K+L + ++  E++     E ++ 
Sbjct: 1570 KESNEIKKKEELQELQEEITEKDNDIKNLKEEIERIEKELQEKEEDMEQMSNNTEELEEL 1629

Query: 1092 IKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFI 1151
              +L ET+   E    K E   IS+  E   +    +              ++++E+E  
Sbjct: 1630 KNKLTETQRLLEEE--KKEKESISNEFEETKEQV--LVELQRVNNEMNKMNEIKQEDE-- 1683

Query: 1152 QERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTEND 1211
             E+  LQE   KL ++++    ++ ++  L  EL+     N+     + +K   L+  +D
Sbjct: 1684 NEKEELQEHINKLKSQIERENEQLKEVSKLKWELSELKTENESMKQMIMNKKSLLDNTDD 1743

Query: 1212 NLLSTVAEL 1220
             +L ++  L
Sbjct: 1744 FILMSLEYL 1752



 Score =  132 bits (319), Expect = 8e-29
 Identities = 188/858 (21%), Positives = 397/858 (46%), Gaps = 84/858 (9%)

Query: 147  LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXX 206
            L+ T +EK+     L+ + + +E    +L+E    K ++ E KNK               
Sbjct: 906  LTQTKQEKEEIQKALEEEKEKLERIETELKEIKEAKQELEEEKNKTIEEKTNLQQELNEN 965

Query: 207  XXXXXE--DTKQQMTKMQENFIAMEAEWK---DEKQRLL-KDIESKDVRISSLEEANKLL 260
                 E   TKQ+  ++     +++ E K   +EK +++ ++ E K+  I S+EE  + +
Sbjct: 966  KKIVEELTQTKQEKEEINNELNSIKEEKKRIEEEKNQIINENKEIKEENIKSIEEKTQEI 1025

Query: 261  EAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIAN 320
             +    I     +L +   +              L    ++    +K ++EE  +     
Sbjct: 1026 NSLTTSIEELKGRLEESKGERIEIEKERDRVISELNDIKLQNEGMKK-QVEEAHN----R 1080

Query: 321  MTELTKKI-----ELLEHLNCQIRQTN---KELENKLATMGTE-SKAVSSPSKKGSPLIS 371
            MTE+ K       E++  LN QI Q N   K++  ++  + T+ S++  +  +    LI 
Sbjct: 1081 MTEMQKSFEGSENEMINSLNNQITQLNEKEKQMNEQVMALQTQLSQSNINLEEVKKDLIE 1140

Query: 372  RKSGRNTASKMKSPWSQ----LSSE--TLNQDTDKKINKNEI----AKLEMVIQSLNKDL 421
             ++     ++ K    Q    ++ E  T+N++ +K  NK E+     K +  I  LNK+ 
Sbjct: 1141 SQNKYTQINEEKDCVEQERNKINEEYKTVNEELEK--NKKELNDLQTKYDNEILELNKNK 1198

Query: 422  VDKEYVIS----EKDTXXXXXXXXXXGKDTLIAQLQLEHQQHME-GPSLIHVGTNTEDV- 475
             +   +I+    EK             K  LI +L        +    L       E++ 
Sbjct: 1199 DELNSLINNLKEEKTNLEEQVKKMEEEKSKLITELSNGSDGVSKLNEELTQTKQEKEEIN 1258

Query: 476  NEIAKVQEQLK--QELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANK--NMIKVKS 531
            NE+  ++E+ K  +E  ++I + N K++ E+ +  EE+  +L  EI+   +  N ++ + 
Sbjct: 1259 NELNSIKEEKKRIEEEKNQIINEN-KEIKEEKEKIEEEKKELLKEIEKEKEGNNQLQNEI 1317

Query: 532  NH-KLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDS 590
            N  + ++K++++   N   + D+NKEI +  EE  +L +++ +++EEK  L   L + + 
Sbjct: 1318 NTIQTRMKEIEE--KNQEIICDNNKEIAKFKEEQENLQKELNQIKEEKSKLITDLSNGND 1375

Query: 591  G-----RMIES-DVYKKMI--EMENLAETRLKAISLLE--SQKFDLVQE-----LHILQQ 635
            G       IE+ +  K+ I  E+E+L E   K    LE  +Q+   V+E     +H L  
Sbjct: 1376 GLSKLNEEIETINKEKEGIRKELESLKEENNKIQDELEQKNQELSKVKEEKEKLIHDLTN 1435

Query: 636  KYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKE---QL 692
              D +     D++Q+++D+     K+V L+ +I+ L +  +EL+    NL  +KE   Q+
Sbjct: 1436 GNDGINQLNEDLNQIKNDKEELTEKNVQLQNEINKLKSENEELS---NNLSFEKEGLKQV 1492

Query: 693  YGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFG 752
               +  ++ ++++++ +++   +E   + ++L   +  +++E +A+IN+E++   Q    
Sbjct: 1493 NEEVNAIKEERDELVKQIKKIEEEKRKVEEEL-NFNGSEVNEQIAQINNEKEQLNQECNE 1551

Query: 753  IDAKIQERDLYIENIESELS----KYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQE 808
            +   ++E    IE IE E      K K  +  L+E I   ++   +L+ + +++   LQE
Sbjct: 1552 LKQNLKELQSKIEEIEQEKESNEIKKKEELQELQEEITEKDNDIKNLKEEIERIEKELQE 1611

Query: 809  KQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQIS 868
            K++   + +   +EL      L +  R++E++  E E  + E ++  + +L E Q +   
Sbjct: 1612 KEEDMEQMSNNTEELEELKNKLTETQRLLEEEKKEKESISNEFEETKEQVLVELQRVNNE 1671

Query: 869  LSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDL 928
            ++ M +     +++ +     E+E  + Q  +  L+S ++R  +E    + + K E+ +L
Sbjct: 1672 MNKMNE-----IKQED-----ENEKEELQEHINKLKSQIER-ENEQLKEVSKLKWELSEL 1720

Query: 929  EIEFNTQIESAIRDKKVL 946
            + E N  ++  I +KK L
Sbjct: 1721 KTE-NESMKQMIMNKKSL 1737



 Score =   99 bits (238), Expect = 5e-19
 Identities = 168/855 (19%), Positives = 359/855 (41%), Gaps = 90/855 (10%)

Query: 804  SYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQ 863
            S+ +      + ++  E    + LA     + V      +IE ENK LQ +N+  L++  
Sbjct: 142  SFSKRNSTENTGHSSSEHSATSSLASETTAEEVNRSVNAQIEEENKRLQNENE-ELKKKC 200

Query: 864  NLQISL------SDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTL 917
            + Q SL      S+M+      + +  + DL +  + +    +  L   L +I +E +++
Sbjct: 201  DAQDSLLKTKMKSEMEAKKKVEILENEKKDLIDKMANE-NDGMSKLNEELTQIKNEKESI 259

Query: 918  ---IVQKKKEIEDLEIEFNTQIESAIRDKK-VLNEKYEKNIEYVTQLEAQLQEYKNNIEN 973
               ++Q K+E E +  E  TQ+++    K+  LN+   +  E + +     +E +  +  
Sbjct: 260  NNELIQTKQEKESINNEL-TQLKTDNDQKENELNQVRHEKDEVIEKFNTSKEENEKIMNE 318

Query: 974  LNMNVEELNKMNLELIDKHVQKQQTQSPDYTE--QYINEINKLNALLKQKDEEIIALNQK 1031
            L+   +E  +   EL ++  + ++ +S   TE     + I+KLN  L Q  +E   +N +
Sbjct: 319  LSQLKQEKEEKENELKEQVKKMEEEKSKLITELSNGSDGISKLNEELTQTKQEKEEINNE 378

Query: 1032 INNAQVSYMSMVSDYE---SKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQ 1088
            +N+ +     +  +     ++  +   + E +EEE + + K++   K+ N +LQ  +   
Sbjct: 379  LNSIKEEKKRIEEEKNQIINENKEIKEEKEKIEEEKKELLKEIEKEKEGNNQLQNEINTI 438

Query: 1089 DDQIKELKE-------------TKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXX 1135
              ++KE++E              K   E    + E   I    +   ++ N +       
Sbjct: 439  QTRMKEIEEKNQEIICDNNKEIAKFKEEQENLQKELNQIKEEKQKTENEKNELVDVKTQK 498

Query: 1136 XXXXXXLKVQEEEEF-------------IQERSVLQEQSAKLNTELQ----ECYTKIIQL 1178
                  LK ++E+ F             ++E++ L E+   +  EL     +  TK +++
Sbjct: 499  ENELNKLKEEKEQIFNEKTTIENSLNQIVEEKNKLTEEKESIKQELDSIKADNSTKELEI 558

Query: 1179 ETLNTE----LTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFE 1234
              +N E       +D V QE+ N ++ +L Q+  E       + +++       D++   
Sbjct: 559  NKINEEKNQLQNDYDTVQQEKEN-IQKELNQIKIEKSQKEEELNKIKEEKQQVEDEKAKL 617

Query: 1235 IAEL--WKQHLAQREADFQKTEHE---LRVQLSAFESKYEQLLDSVQSSTQE----ETNK 1285
            I ++      L +      K + E   +  +L+  +++ + + +    + +E    E   
Sbjct: 618  ITDIANGNDGLTKLNEVIDKLKDEKENISNELNQIKNERDNISNEFNKTKEEIKQKENET 677

Query: 1286 IVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXX 1345
            I   E+ + L N+L   +E  + ++++ A +  + E   +++ ++K              
Sbjct: 678  IQLNEEKSVLLNELNQIKEEKQKIEDEKAVIQQEKENEITKLNEDKTVIENELNQIKTEK 737

Query: 1346 XXXXXDL-RTENQSYKQMQEQSIL-----NINEENAQLKKSSXXXXXXXXXXXXRVNDAE 1399
                 +L +T+++  K   E+S L     N N+  ++L +               +N  +
Sbjct: 738  QEIENELNQTKDEKQKIEDEKSKLITELSNGNDGISKLNEELTQTKQEKENVLNELNQIK 797

Query: 1400 AKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYE---KE 1456
             +      Q   K++E+  + ++    L Q+N+E   + ++       + +   E   K+
Sbjct: 798  NEFASFKEQNTQKENELKDENNKVQQELEQKNNEVSKLEEEKGNISNELSNTKQELEQKK 857

Query: 1457 SELAILRLKMHENANHYETMQKESEIERVKLIEELN------VKITESVSLNKQ-VAELN 1509
             E+  +  +  E  N  +   K+ E E+ KLI EL+       K+ E ++  KQ   E+ 
Sbjct: 858  QEIITITQEKEEKENELKEQVKKIEEEKSKLITELSNGSDGISKLNEELTQTKQEKEEIQ 917

Query: 1510 KALEEEVAKTNEMQTALE-----NQEIEIVTLN--DEITNLQNMVRASSSKIQKHVSFAS 1562
            KALEEE  K   ++T L+      QE+E       +E TNLQ  +  +    +K V   +
Sbjct: 918  KALEEEKEKLERIETELKEIKEAKQELEEEKNKTIEEKTNLQQELNEN----KKIVEELT 973

Query: 1563 DTKQGRDEQLDNTMN 1577
             TKQ + E+++N +N
Sbjct: 974  QTKQEK-EEINNELN 987



 Score = 72.9 bits (171), Expect = 7e-11
 Identities = 113/543 (20%), Positives = 235/543 (43%), Gaps = 35/543 (6%)

Query: 218  MTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQE 277
            ++K+ E     + E K+E    L  I+ +  RI   EE N+++   + EI  E  K+ +E
Sbjct: 1240 VSKLNEELTQTKQE-KEEINNELNSIKEEKKRIE--EEKNQIINENK-EIKEEKEKIEEE 1295

Query: 278  LEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIA-NMTELTKKIELLEHLNC 336
             ++              L  + I        EIEEK    I  N  E+ K  E  E+L  
Sbjct: 1296 KKELLKEIEKEKEGNNQLQNE-INTIQTRMKEIEEKNQEIICDNNKEIAKFKEEQENLQK 1354

Query: 337  QIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSG-RNTASKMKSPWSQLSSETLN 395
            ++ Q  +E    +  +   +  +S  +++   +   K G R     +K   +++  E   
Sbjct: 1355 ELNQIKEEKSKLITDLSNGNDGLSKLNEEIETINKEKEGIRKELESLKEENNKIQDELEQ 1414

Query: 396  QDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLE 455
            ++ +    K E  KL   + + N  +      +++                  I +L+ E
Sbjct: 1415 KNQELSKVKEEKEKLIHDLTNGNDGINQLNEDLNQIKNDKEELTEKNVQLQNEINKLKSE 1474

Query: 456  HQQHMEGPSLIHVGTN--TEDVNEIAKVQEQLKQELN--DEIKDVNVKDLIEKLKSAEEQ 511
            +++     S    G     E+VN I + +++L +++   +E K    ++L        EQ
Sbjct: 1475 NEELSNNLSFEKEGLKQVNEEVNAIKEERDELVKQIKKIEEEKRKVEEELNFNGSEVNEQ 1534

Query: 512  ITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNK-----EIVRLTEELHH 566
            I Q+N+E +  N+   ++K N    LK++Q  I+   +  +SN+     E+  L EE+  
Sbjct: 1535 IAQINNEKEQLNQECNELKQN----LKELQSKIEEIEQEKESNEIKKKEELQELQEEITE 1590

Query: 567  LSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMEN-LAET-RLKAISLLE---- 620
                +  L+EE   ++  L + +      S+  +++ E++N L ET RL      E    
Sbjct: 1591 KDNDIKNLKEEIERIEKELQEKEEDMEQMSNNTEELEELKNKLTETQRLLEEEKKEKESI 1650

Query: 621  SQKFDLVQELHILQ-QKYDEVEDKLADISQLQSDQVCSEIKSVH-LEEQIDALSASKKEL 678
            S +F+  +E  +++ Q+ +   +K+ +I Q   ++     + ++ L+ QI+  +   KE+
Sbjct: 1651 SNEFEETKEQVLVELQRVNNEMNKMNEIKQEDENEKEELQEHINKLKSQIERENEQLKEV 1710

Query: 679  ALV---IENLKLDKEQLYGTIKD----LENDKEDIMNKLQNYIQENMDLTDKLEKMSAEK 731
            + +   +  LK + E +   I +    L+N  + I+  L+    +++ +T K+E +  E 
Sbjct: 1711 SKLKWELSELKTENESMKQMIMNKKSLLDNTDDFILMSLEYLYFDSVWVTLKMELLDEED 1770

Query: 732  ISE 734
            + +
Sbjct: 1771 LDD 1773


>UniRef50_A2FD36 Cluster: Viral A-type inclusion protein, putative;
            n=1; Trichomonas vaginalis G3|Rep: Viral A-type inclusion
            protein, putative - Trichomonas vaginalis G3
          Length = 3977

 Score =  210 bits (514), Expect = 2e-52
 Identities = 304/1481 (20%), Positives = 622/1481 (41%), Gaps = 121/1481 (8%)

Query: 147  LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXX 206
            L NTI++  +A   L  K   ++  +++LQ+   EK+Q+    +K  T            
Sbjct: 245  LENTIEQLKSANKELSDKNVEIQAKLINLQK---EKEQLTSTNDKLLTETENLKKEIDEL 301

Query: 207  XXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDI--ESKDV--RISSLEEANKLLEA 262
                 E   + +   Q    +++ E K   +++++D+  E  D+  +I  LE  NK + +
Sbjct: 302  NNANKELNVKSINLQQ----SLDNE-KQNNKKMIQDLNKEKTDLISKIEKLEMDNKEMNS 356

Query: 263  ARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMT 322
                ++  ++ L  + +                 ++ IE   +E TE+        + + 
Sbjct: 357  KLNNVNTSYNDLDAKNQNNQTKVNNL--------EKIIEKLIKENTELANNNKNNNSKID 408

Query: 323  ELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKM 382
            EL  + + L   +  +   N+ L+ K+  +  E   +    +K   L S   G  +    
Sbjct: 409  ELQNQNKDLISASNDMNTKNQSLQTKIDQLNKEKTELE---EKNKVLKSNLEGLKSDLLS 465

Query: 383  KSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXX 442
            K+  S   +E L +  D+  N+N++    +  Q+   D ++KE    + D          
Sbjct: 466  KNQESTKKNENLQKIIDQLQNENKLLSSNLENQTKLNDDLNKE----KSDLQSKIEELEK 521

Query: 443  XGKDTLIAQLQLEHQQHMEGPSLIH-VGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDL 501
              KD L + L+  H+   E  + I+ +  N +++    + Q +L  +LN E  D      
Sbjct: 522  NNKD-LTSNLENNHKTIEELSNKINDLQNNNKELTSNLEDQNKLNDDLNKEKAD------ 574

Query: 502  IEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLT 561
               L+S  E+++  N+E++++NKN    K N + K+ + +K ID   K  +  +E  +++
Sbjct: 575  ---LQSKIEELSTKNEELESSNKNE---KENLQNKVDEFEKIIDQLRKEKEVLEENEKVS 628

Query: 562  EELHHLSQKVAE-LEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLE 620
            +       KV E L  EK +LQ  +   +       D+   + E+ N  ++ L   SL  
Sbjct: 629  KTNIDDDYKVIEELNNEKSDLQSKIDQLEKNN---KDLTTNL-ELSNKEKSDL---SLEN 681

Query: 621  SQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELAL 680
              K   + EL  L  K +   +KL    QLQ  ++  E  +  L+++ + LS+   +L  
Sbjct: 682  ENKRKEIDELKSLNNKTNNDIEKL----QLQIQEL--EKSNEQLQKEKEVLSSENNQLKS 735

Query: 681  VIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKIN 740
             +EN   +KE     I  L  +K D+ +K++     N +L   LE  +  K++++L   N
Sbjct: 736  NVENS--EKE-----IGILNKEKADLQSKVEELDNNNKELASNLENQN--KLNKVLNNEN 786

Query: 741  HEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKAD 800
             + QSKI+    +  K QE +       +E    ++RI  LE+ I  ++    +LE +++
Sbjct: 787  SDLQSKIEE---LTTKNQELESSNIETNNEKENLQARINELEKIIDELQKENENLETESN 843

Query: 801  QLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLE 860
             L + LQ  +K  ++    +++L +++  L  +++     + +I   NK+LQ KN  L  
Sbjct: 844  HLRTDLQNNEKTIADLNKDKNDLTSKIGELEKNNKEFTTLIDKINASNKDLQTKNDELQS 903

Query: 861  ENQNLQISLSDMQQHYNALVEKAN--RTDLAESEST--KYQTQLRDLESNLKRITHEHQT 916
            +   L+  L  + +  + L+ K    +T + + + T      + +DL++ ++ +  E+  
Sbjct: 904  KVDLLEKILDQLNKDKSDLITKLEELQTSIDQMKQTNENLNKENKDLQNKIEELLEEND- 962

Query: 917  LIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNM 976
               +   E E    E    I+    +K  L  K+E++ +     +  + E     E L  
Sbjct: 963  ---KANNENESKNKELQQIIDQLAEEKLSLQNKFEESEKNAKDNQKIIDELIAENEKLTS 1019

Query: 977  NVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQ 1036
            +  E  K+ LE +   +++ +       E+   EI K    LK ++  I+  +   NN  
Sbjct: 1020 SNNE-EKVELESLKNSLEETKQNDDKLVEELSKEIEK----LKNENNSILENSDSKNNEN 1074

Query: 1037 VSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIK--- 1093
               +  +   +S L     KL    E+ ++V + L++ +   +E    + +Q +++K   
Sbjct: 1075 QQIIDQLKKEKSDLMNQVDKLTKKNEDQEKVIQDLINDQNQKDEENKQMNDQSNELKSQI 1134

Query: 1094 ------------ELKETK-----LTFEMNIPKTEGMIISSTIEPMSDDANN-VDXXXXXX 1135
                        +L++ K     L  E  I ++E   +   +E    + N  +D      
Sbjct: 1135 EKISIENETLKSDLQKNKESNGELMKEREISQSELEELKKLLEETKQNDNKLIDKLRNEN 1194

Query: 1136 XXXXXXLKVQEE------EEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHD 1189
                  L +  +      ++F +E S L  Q  +LN    E    I  LE   + LT  +
Sbjct: 1195 QSLNNQLDMNNKDHQQIIDQFTKEESDLMSQIEELNALNNELNVNIQNLEQDKSNLTKQN 1254

Query: 1190 VVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWK--QHLAQRE 1247
                  +N+ K + + L+ EN+ L S    L+S +    ++   +  +L K  + L   +
Sbjct: 1255 EELNALLNETKLQNQNLSNENETLRSNNERLQSELKQNEEKSKSDFDQLTKDLETLKSEQ 1314

Query: 1248 ADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLR 1307
            ++  K   EL+ + +  E    +L +     T   T++   +EQ+   ++ L     +  
Sbjct: 1315 SNKDKMIDELQNKTNDLEESIGKLNEEKAKITDSLTDRDQKIEQLNKEKSDLISDINNFE 1374

Query: 1308 NLQEKYADVINQIEILRSEI--EDEKVAFXXXXXXXXXXXXXXXXDLR-TENQSYKQMQE 1364
              Q++  D I+ +     ++  E+EK+                  + +  E +S  Q   
Sbjct: 1375 ASQKELNDKIDSLNSANKDLNQENEKLKSQISSLENENSSLQSANNSKDKEIKSINQQLS 1434

Query: 1365 QSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYT 1424
            ++I + +   +Q +  +              + +E ++ EL ++LE   +EI Q   +  
Sbjct: 1435 ETISSFDNYKSQHESEAEALSNKLNNLEANKDKSEKELEELRNELEKLQNEI-QIREQRE 1493

Query: 1425 ITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIER 1484
              L+ +N+E  N+ +++      +     + + E  IL+  + EN  +Y+ +  E   E 
Sbjct: 1494 KELSNQNEELMNILEKMKSELNDVNMNNEQLDQEKEILKKSLEENQQNYDQLIDELSKEI 1553

Query: 1485 VKLIEELNVKITESVSLNKQVAEL-----NKALEEEVAKT--NEMQTALENQEIEIVTLN 1537
              L ++L  K  +S S   ++ EL     N + E E  K+  NE++  L++       +N
Sbjct: 1554 EVLKKQLLTKDADSNSSKHEIDELQSKIQNLSSENENLKSTNNELKQNLDDILKNNEQIN 1613

Query: 1538 DEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNK 1578
             E+T  +   +   S+I+       + KQ  DEQL + ++K
Sbjct: 1614 SELTETKQTNKDLLSQIESLKKVLEENKQ-NDEQLVDELSK 1653



 Score =  203 bits (495), Expect = 4e-50
 Identities = 302/1519 (19%), Positives = 645/1519 (42%), Gaps = 138/1519 (9%)

Query: 93   SLANTLK-QKEILMEKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTI 151
            SL+N LK Q E+L ++ +  K   +R+   I +                  ++ +L   +
Sbjct: 1938 SLSNKLKPQIEVLSKENESLKSEIQRNHENIEKLQQKLDESQQTNENSS-NEIDNLKKLL 1996

Query: 152  KEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXX 211
            +E +N  + L    + ++  I D  + I E ++  +A N   +                 
Sbjct: 1997 EEANNNHNQLMNDFENLKHEISDKDKMIQELEKRNDANNNQNSDLSAKLKESEAKISELD 2056

Query: 212  EDTKQQMTKMQENFIAMEAEWKDEKQRL---LKDIESKDVRIS-----SLEEANKLLEAA 263
               ++   ++ E  + M  E K+  Q +   +++I +++V +      S E +NKL    
Sbjct: 2057 SQIEKYKQEL-EKLMKMNNELKETVQEMENQIQNISNENVNLKTEVDKSKENSNKLQNDL 2115

Query: 264  RFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTE 323
              E    +  L  ++E               +  +  +    ++   +E  +L+ +    
Sbjct: 2116 N-EAKQNNENLLSQIESLKKLLEENDANFEKMKSELNDAKMNKEHSDQENETLKKSLEEN 2174

Query: 324  LTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSG-RNTASKM 382
                 +L++ L+ +I +  K+L  K     +    +     K   L S     ++T +++
Sbjct: 2175 QQNYDQLVDELSKEIEELKKQLLTKAEESNSSKHEIDELQSKIQNLSSENENLKSTNNEL 2234

Query: 383  KSPWSQL--SSETLNQDTD--KKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXX 438
            K     +  ++E +N +    K+ NK+ ++++E + + L ++  + E ++ E        
Sbjct: 2235 KQNLDDILKNNEQINSELTETKQTNKDLLSQIESLKKVLEENKQNDEQLVDELSKAPDEM 2294

Query: 439  XXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELN------DE 492
                  KD  I +L  E ++ +      H   + + + E+ K + +L  +++      D+
Sbjct: 2295 KHEQQKKDNRIDELTKE-KETLYNTLNSHDKDHQQIIEEMNKEKSELGSQIHEYESELDK 2353

Query: 493  IKDVNVKDLIE---KLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNF-S 548
            +K +N K+L E   KL   + ++ + N+++   N ++I  +++    + + +  ID   S
Sbjct: 2354 LKSLN-KELNENNTKLNQDKSELIKQNEDLTRNNNDLINAQNDKDRIINENKAKIDELPS 2412

Query: 549  KVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEM--- 605
             ++D    +  L+ E + L Q+V +L+ E G+ + +    +    IES+  KK +E    
Sbjct: 2413 LLNDLQSHLQNLSNENNSLKQEVEKLQTELGDSKQN----EEKSKIESEQMKKSLEETKQ 2468

Query: 606  --ENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVH 663
              E L +   K I  L++++ +  + +  L  K + +   L D +  + +Q+  ++    
Sbjct: 2469 NDEQLVDELTKEIEKLKNEQLNKDRTIQNLTNKNESINKNL-DSNNKEYEQIIDQLNQDL 2527

Query: 664  LEEQ--IDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLT 721
             E +  ++       EL L+ + L+ D E L     DL N  E++  K +N I  N+  T
Sbjct: 2528 SESKSKLNDYETKMNELNLLNKELQKDNETLKENQSDLINQIEELSKKNENLI--NLQGT 2585

Query: 722  DKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRL 781
            +    +  +++ +L+ K+N E+   IQ          E +   +N      K +S    L
Sbjct: 2586 NSNLVLKNDELQQLIDKLNKEKSDLIQ----------ENERLTKNNGESNEKLQS----L 2631

Query: 782  EESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQL 841
            ++ I  +++     +++  Q+   L  K+K      +++ E  N+L VL       +  L
Sbjct: 2632 DQMIETVKNNSSEKDKENHQIIDQLN-KEKLDLSSKLKDYE--NQLDVL-------KSSL 2681

Query: 842  LEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLR 901
             E+  +NKELQ  N IL +EN+ L   +S ++   N+ ++  N     E E      +L+
Sbjct: 2682 KELNDKNKELQNGNDILKQENETLTPKISSLESE-NSSLKSTNEIKDKEIE------ELK 2734

Query: 902  DLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLE 961
               S + ++  +H++ +  ++K+ E    E   Q+E    + ++  ++ ++      +L 
Sbjct: 2735 QKLSEISQLNSQHESDLDSRRKQFEKELEELRNQLEKLQNEIQIREQRGKELSNQNEELM 2794

Query: 962  AQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQK 1021
              L++ K+ + +  MN E  ++ N E + K +++ Q       ++   EI +L   L  K
Sbjct: 2795 NNLEKMKSELNDAKMNKEHSDQEN-ETLKKSLEENQQNYDQLVDELSKEIEELKKQLLTK 2853

Query: 1022 DEEIIALNQKINNAQVSYMSMVSDYES----------KLAQFTTKLENMEEEMQRVSKQL 1071
             EE  +   +I+  Q    ++ S+ E+          ++      L+N ++ ++ ++K++
Sbjct: 2854 AEESNSSKHEIDELQSKIQNLSSENENLKSTNNELKQQIESLKNDLQNKDQIVEELTKEI 2913

Query: 1072 LDS-KQHNEELQILVREQDDQIKELKE-TKLTFEM--NIPKTEGMIISSTI--EPMSDDA 1125
              S KQ +E  ++L ++Q D +K++++ TK   EM       E +I    I  E ++ + 
Sbjct: 2914 DSSNKQSHENNELLNQKQLDLMKQIEDLTKKQGEMLKQNQNQENIINDLKIKNEELTKEG 2973

Query: 1126 NNVDXXXXXXXXXXXXLK--VQE-EEEFIQERSVLQEQSA-------KLNTELQECYTKI 1175
            NN D             K  +Q    E  + +S LQ           KLN+  Q     +
Sbjct: 2974 NNKDKVINELNKSLNDFKSLIQNLSNENEKLKSALQNSQGNNADLQQKLNSTQQNDQNLL 3033

Query: 1176 IQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEI 1235
             Q+E L   L      N++  + L ++++    EN N    + +LR   +  ++ +  +I
Sbjct: 3034 NQIELLKKSLQ----ENKQNEDNLVNEIQNQKIENQNKDQIIEDLRKK-NEELNLKQQQI 3088

Query: 1236 AELW---KQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQ- 1291
             + +   K  L  +      + +EL       E +   L++ +    ++  N+I+  +Q 
Sbjct: 3089 QDQFNKEKSGLISKLQGLNLSGNELLSNNEKLEQEQSDLMNQINDLRKK--NEILNQQQA 3146

Query: 1292 -----VTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXX 1346
                 +   Q K+Q+ EE    LQ K  + +N  E  +++I+  K               
Sbjct: 3147 NNNQIIKECQEKIQNYEESNNELQRKLNEAMNNNENAKNQIDQLK----KLLEETKQNDD 3202

Query: 1347 XXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELT 1406
                +L  E +  K  Q+    NIN+ +A  K  S            + ND  +K  +  
Sbjct: 3203 KLVEELTKEIEKLKNEQQSKDQNINDLSALNKDKS---------SLIQQNDDLSKKTQEF 3253

Query: 1407 HQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKM 1466
            +  +   +++ +   +   +L Q+N E  N      E ++ I+ LT +K S+LA      
Sbjct: 3254 YNSQQNQAQMIEDLKKQNESL-QKNLEINN-----NETQQNIDQLTKDK-SDLASKLHDY 3306

Query: 1467 HENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTAL 1526
                N   ++ KE   E+  +IE+ N + ++ + +N  +   N  L++ + + N+ +T L
Sbjct: 3307 EAKINDLNSLIKELN-EKNAIIEKKNYEFSQQLEVNNDLISKNNQLQQTIDQLNKDKTVL 3365

Query: 1527 ENQEIEIVTLNDEITNLQN 1545
              Q  ++   N+EITN  N
Sbjct: 3366 SKQIQDLANKNNEITNQLN 3384



 Score =  202 bits (492), Expect = 8e-50
 Identities = 296/1390 (21%), Positives = 596/1390 (42%), Gaps = 121/1390 (8%)

Query: 231  EWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXX 290
            E   EK  L   I   +  +  L+  NK L     +++ + S+L ++ E           
Sbjct: 2332 EMNKEKSELGSQIHEYESELDKLKSLNKELNENNTKLNQDKSELIKQNEDLTRNNNDLIN 2391

Query: 291  XXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKL- 349
                  K  I    E K +I+E  SL    + +L   ++ L + N  ++Q  ++L+ +L 
Sbjct: 2392 AQND--KDRIIN--ENKAKIDELPSL----LNDLQSHLQNLSNENNSLKQEVEKLQTELG 2443

Query: 350  -ATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIA 408
             +    E   + S   K S   ++++      ++     +L +E LN+D   +  +N   
Sbjct: 2444 DSKQNEEKSKIESEQMKKSLEETKQNDEQLVDELTKEIEKLKNEQLNKD---RTIQNLTN 2500

Query: 409  KLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHV 468
            K E + ++L+ +  + E +I + +             +T + +L L +++  +    +  
Sbjct: 2501 KNESINKNLDSNNKEYEQIIDQLNQDLSESKSKLNDYETKMNELNLLNKELQKDNETLKE 2560

Query: 469  GTNT--EDVNEIAKVQEQL--KQELNDEI--KDVNVKDLIEKLKSAEEQITQLNDEIDAA 522
              +     + E++K  E L   Q  N  +  K+  ++ LI+KL   +  + Q N+ +   
Sbjct: 2561 NQSDLINQIEELSKKNENLINLQGTNSNLVLKNDELQQLIDKLNKEKSDLIQENERLTKN 2620

Query: 523  NKNMIKVKSNHKLK-LKQMQKTIDNFSKVSDS-NKEIV-RLTEELHHLSQKVAELEEEKG 579
            N      +SN KL+ L QM +T+ N S   D  N +I+ +L +E   LS K+ + E +  
Sbjct: 2621 NG-----ESNEKLQSLDQMIETVKNNSSEKDKENHQIIDQLNKEKLDLSSKLKDYENQLD 2675

Query: 580  NLQLHLVDY-DSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYD 638
             L+  L +  D  + +++     +++ EN  ET    IS LES+   L     I  ++ +
Sbjct: 2676 VLKSSLKELNDKNKELQNG--NDILKQEN--ETLTPKISSLESENSSLKSTNEIKDKEIE 2731

Query: 639  EVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKD 698
            E++ KL++ISQL S           L+ +        +EL   +E L+ + +      K+
Sbjct: 2732 ELKQKLSEISQLNSQHESD------LDSRRKQFEKELEELRNQLEKLQNEIQIREQRGKE 2785

Query: 699  LENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAK-INHEEQSKIQTQFGIDAKI 757
            L N  E++MN L+    E  D   K+ K  +++ +E L K +   +Q+  Q    +  +I
Sbjct: 2786 LSNQNEELMNNLEKMKSELNDA--KMNKEHSDQENETLKKSLEENQQNYDQLVDELSKEI 2843

Query: 758  QE--RDLYIENIESELSKYK-----SRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQ 810
            +E  + L  +  ES  SK++     S+I  L      ++     L+++ + L + LQ K 
Sbjct: 2844 EELKKQLLTKAEESNSSKHEIDELQSKIQNLSSENENLKSTNNELKQQIESLKNDLQNKD 2903

Query: 811  KAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLS 870
            +   E T +E +  N+ +   +++ ++ ++ L++  + ++L KK   +L++NQN +  ++
Sbjct: 2904 QIVEELT-KEIDSSNKQS--HENNELLNQKQLDLMKQIEDLTKKQGEMLKQNQNQENIIN 2960

Query: 871  DMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEI 930
            D++     L ++ N  D   +E  K     + L  NL     + ++ +   +    DL+ 
Sbjct: 2961 DLKIKNEELTKEGNNKDKVINELNKSLNDFKSLIQNLSNENEKLKSALQNSQGNNADLQQ 3020

Query: 931  EFNT---QIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLE 987
            + N+     ++ +   ++L +  ++N +    L  ++Q  K   +N +  +E+L K N E
Sbjct: 3021 KLNSTQQNDQNLLNQIELLKKSLQENKQNEDNLVNEIQNQKIENQNKDQIIEDLRKKNEE 3080

Query: 988  LIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYE 1047
            L   ++++QQ Q   + ++    I+KL  L      E+++ N+K+   Q   M+ ++D  
Sbjct: 3081 L---NLKQQQIQD-QFNKEKSGLISKLQGL-NLSGNELLSNNEKLEQEQSDLMNQINDLR 3135

Query: 1048 SKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVRE----------QDDQIKEL-K 1096
             K      +  N  + ++   +++ + ++ N ELQ  + E          Q DQ+K+L +
Sbjct: 3136 KKNEILNQQQANNNQIIKECQEKIQNYEESNNELQRKLNEAMNNNENAKNQIDQLKKLLE 3195

Query: 1097 ETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSV 1156
            ETK   +  + +    I     E  S D N  D               +++   IQ+   
Sbjct: 3196 ETKQNDDKLVEELTKEIEKLKNEQQSKDQNINDLSALN----------KDKSSLIQQNDD 3245

Query: 1157 LQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLST 1216
            L +++ +     Q     I  L+  N  L  +  +N    N+ +  ++QL  +  +L S 
Sbjct: 3246 LSKKTQEFYNSQQNQAQMIEDLKKQNESLQKNLEINN---NETQQNIDQLTKDKSDLASK 3302

Query: 1217 VAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQ 1276
            + +  + I+        ++  L K+ L ++ A  +K  +E   QL        +     Q
Sbjct: 3303 LHDYEAKIN--------DLNSLIKE-LNEKNAIIEKKNYEFSQQLEVNNDLISKNNQLQQ 3353

Query: 1277 SSTQEETNKIVTMEQVTSLQNKLQDKEEHLRN-----LQEKY-ADVINQ-IEILRSEIED 1329
            +  Q   +K V  +Q+  L NK  +    L N     L+ K  +D +NQ +  L  E+  
Sbjct: 3354 TIDQLNKDKTVLSKQIQDLANKNNEITNQLNNKDKIILESKQKSDELNQSLSNLMKELHT 3413

Query: 1330 EKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXX 1389
             K A                 +L+ + +  K++ + +  N N+    L K          
Sbjct: 3414 LK-ANNDDLNSQISQSKQNEENLQLQIEKQKKLLQDTKQNDNKLVDDLSKEVETLTSEKL 3472

Query: 1390 XXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIE 1449
                 +    AK   +  QL+ K+ EI ++  ++         + E  +Q+    EK + 
Sbjct: 3473 KNEEIIKQNNAKYSGILKQLQQKNEEINKEKEQF-------KHDLEGEKQK---NEKLVN 3522

Query: 1450 DLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVS-LNKQVAEL 1508
            DL   K+ +L+    + +E   HY    K++  +    I   N +  E++  L KQ+  L
Sbjct: 3523 DLNQTKD-KLS----QENEKLKHYLVAFKQNNEQ----ITADNKQKDENIQQLMKQINSL 3573

Query: 1509 NKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGR 1568
               L+E+    ++     EN +  I  LN E  +L + +   S K  + +S  ++  Q  
Sbjct: 3574 KSQLQEDEKLKSQFAKMKENYDSLINKLNQENKSLTHSLN-ESLKHNEELSKNNEKLQQN 3632

Query: 1569 DEQLDNTMNK 1578
            +E L N +N+
Sbjct: 3633 NELLSNKLNQ 3642



 Score =  201 bits (490), Expect = 1e-49
 Identities = 299/1471 (20%), Positives = 630/1471 (42%), Gaps = 117/1471 (7%)

Query: 150  TIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXX 209
            TI+E  N ++ LQ   K + + + D Q K+N  D + + K    +               
Sbjct: 536  TIEELSNKINDLQNNNKELTSNLED-QNKLN--DDLNKEKADLQSKIEELSTKNEELESS 592

Query: 210  XXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISL 269
               + +    K+ E F  +  + + EK+ L    E++ V  +++++  K++E    E++ 
Sbjct: 593  NKNEKENLQNKVDE-FEKIIDQLRKEKEVLE---ENEKVSKTNIDDDYKVIE----ELNN 644

Query: 270  EHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIE 329
            E S L  +++Q                K+  + S E + + +E   L+  N  +    IE
Sbjct: 645  EKSDLQSKIDQLEKNNKDLTTNLELSNKEKSDLSLENENKRKEIDELKSLN-NKTNNDIE 703

Query: 330  LLEHLNCQIRQTNKELENKLATMGTESKAVSSP---SKKGSPLISRKSG--RNTASKMKS 384
             L+    ++ ++N++L+ +   + +E+  + S    S+K   +++++    ++   ++ +
Sbjct: 704  KLQLQIQELEKSNEQLQKEKEVLSSENNQLKSNVENSEKEIGILNKEKADLQSKVEELDN 763

Query: 385  PWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXG 444
               +L+S   NQ+   K+  NE + L+  I+ L     + E    E +            
Sbjct: 764  NNKELASNLENQNKLNKVLNNENSDLQSKIEELTTKNQELESSNIETNNEKENLQARINE 823

Query: 445  KDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEK 504
             + +I +LQ E++ ++E  S  H+ T+ ++        E+   +LN +  D+  K  I +
Sbjct: 824  LEKIIDELQKENE-NLETESN-HLRTDLQN-------NEKTIADLNKDKNDLTSK--IGE 872

Query: 505  LKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSK-VSDSNKEIVRLTEE 563
            L+   ++ T L D+I+A+NK++       + K+  ++K +D  +K  SD   ++  L   
Sbjct: 873  LEKNNKEFTTLIDKINASNKDLQTKNDELQSKVDLLEKILDQLNKDKSDLITKLEELQTS 932

Query: 564  LHHLSQKVAELEEEKGNLQL---HLVDYDSGRMIESDVYKKMIE--MENLAETRLKAISL 618
            +  + Q    L +E  +LQ     L++ +     E++   K ++  ++ LAE +L   + 
Sbjct: 933  IDQMKQTNENLNKENKDLQNKIEELLEENDKANNENESKNKELQQIIDQLAEEKLSLQNK 992

Query: 619  LESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKEL 678
             E  + +      I+ +   E E KL   S    ++V  E     LEE         +EL
Sbjct: 993  FEESEKNAKDNQKIIDELIAENE-KLT--SSNNEEKVELESLKNSLEETKQNDDKLVEEL 1049

Query: 679  ALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAK 738
            +  IE LK +   +        N+ + I+++L+    + M+  DKL K + ++   +   
Sbjct: 1050 SKEIEKLKNENNSILENSDSKNNENQQIIDQLKKEKSDLMNQVDKLTKKNEDQEKVIQDL 1109

Query: 739  INHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERK 798
            IN + Q K +    ++ +  E    IE I  E    KS + + +ES   +   R   + +
Sbjct: 1110 INDQNQ-KDEENKQMNDQSNELKSQIEKISIENETLKSDLQKNKESNGELMKEREISQSE 1168

Query: 799  ADQLGSYLQE-KQ---KAYSEYTIQEDELVNRLAVL-MDHDRVVEKQLLEIEHENKELQK 853
             ++L   L+E KQ   K   +   +   L N+L +   DH +++++   E      ++++
Sbjct: 1169 LEELKKLLEETKQNDNKLIDKLRNENQSLNNQLDMNNKDHQQIIDQFTKEESDLMSQIEE 1228

Query: 854  KNQILLEENQNLQ------ISLSDMQQHYNALVEK--------ANRTDLAESESTKYQTQ 899
             N +  E N N+Q       +L+   +  NAL+ +        +N  +   S + + Q++
Sbjct: 1229 LNALNNELNVNIQNLEQDKSNLTKQNEELNALLNETKLQNQNLSNENETLRSNNERLQSE 1288

Query: 900  LRDLE----SNLKRITHEHQTLIVQ---KKKEIEDLEIEFNTQIESAIR---DKKVLNEK 949
            L+  E    S+  ++T + +TL  +   K K I++L+ + N   ES  +   +K  + + 
Sbjct: 1289 LKQNEEKSKSDFDQLTKDLETLKSEQSNKDKMIDELQNKTNDLEESIGKLNEEKAKITDS 1348

Query: 950  YEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKM--NLELIDKHVQKQQTQSPDYTEQY 1007
                 + + QL  +  +  ++I N   + +ELN    +L   +K + ++  +        
Sbjct: 1349 LTDRDQKIEQLNKEKSDLISDINNFEASQKELNDKIDSLNSANKDLNQENEKLKSQISSL 1408

Query: 1008 INEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRV 1067
             NE + L +    KD+EI ++NQ+++    S+ +  S +ES+    + KL N+E    + 
Sbjct: 1409 ENENSSLQSANNSKDKEIKSINQQLSETISSFDNYKSQHESEAEALSNKLNNLEANKDKS 1468

Query: 1068 SKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANN 1127
             K+L + +   E+LQ      + QI+E +E +L+        +   + + +E M  + N+
Sbjct: 1469 EKELEELRNELEKLQ-----NEIQIREQREKELS-------NQNEELMNILEKMKSELND 1516

Query: 1128 VDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTG 1187
            V+            LK   EE       ++ E S ++    ++  TK     +       
Sbjct: 1517 VNMNNEQLDQEKEILKKSLEENQQNYDQLIDELSKEIEVLKKQLLTKDADSNS------- 1569

Query: 1188 HDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQRE 1247
                ++ +I++L+SK++ L++EN+NL ST  EL+ ++   +       +EL      Q  
Sbjct: 1570 ----SKHEIDELQSKIQNLSSENENLKSTNNELKQNLDDILKNNEQINSEL--TETKQTN 1623

Query: 1248 ADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTME-QVTSLQNKLQDKEEHL 1306
             D       L+  L   +   EQL+D +  +  E  ++    + ++  L  + +     L
Sbjct: 1624 KDLLSQIESLKKVLEENKQNDEQLVDELSKAPDEMKHEQQKKDNRIDKLTKEKETLHNTL 1683

Query: 1307 RNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXD---LRTENQSYKQMQ 1363
             +  + +  +I ++   +SE+E E                    D   L  +N+      
Sbjct: 1684 NSHDKDHQQIIEEMNKEKSELESELEKLKSLNKELNENNTKLNQDKSELIKQNEDLTNDN 1743

Query: 1364 EQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEY 1423
                  INE   ++ + S              N+ ++   E+  Q E  + ++  +  + 
Sbjct: 1744 NHKDEFINENQVKIDELSSLLNDLKSQLQNLSNENDSLKQEIEKQKETNE-KLQSELEDS 1802

Query: 1424 TITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEI- 1482
               L +   E + +++ L E ++  E L  E   E+  L+          E M K+ +I 
Sbjct: 1803 KENLEKSKSEIDPIQKSLEETKQNDEQLVDELTKEIEKLK---------NEQMTKDQKID 1853

Query: 1483 ERVKLIEELNVKITESVSLNKQVA-ELNKALEEEVAKTNEMQ---TALENQEIEIVTLND 1538
            E  K  + LN  + ++   N Q+  +LNK   +  +K NE++   + L +Q   +   ND
Sbjct: 1854 ELTKENQSLNSSLEDNNKENDQIIDQLNKEKSDYESKLNELKQDHSDLMDQIESLAKKND 1913

Query: 1539 EI----TNLQNMVRASSSKIQKHVSFASDTK 1565
            E+     N   ++  ++ +I++ VS ++  K
Sbjct: 1914 ELIKENNNKDQIINDNNQRIEELVSLSNKLK 1944



 Score =  196 bits (479), Expect = 3e-48
 Identities = 304/1360 (22%), Positives = 604/1360 (44%), Gaps = 132/1360 (9%)

Query: 321  MTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISR-------K 373
            + ELT+  E+L   N ++ + N++L  +  ++ T   +  S + +    I +        
Sbjct: 200  LDELTQNNEILSKDNEKLSKENEQLNQENTSLSTLLGSAKSTNLELENTIEQLKSANKEL 259

Query: 374  SGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEM-VIQSLNKDLVDK-----EYV 427
            S +N   + K    Q   E L    DK + + E  K E+  + + NK+L  K     + +
Sbjct: 260  SDKNVEIQAKLINLQKEKEQLTSTNDKLLTETENLKKEIDELNNANKELNVKSINLQQSL 319

Query: 428  ISEKDTXXXXXXXXXXGKDTLIAQLQ-LEHQQHMEGPSLIHVGTNTED-----------V 475
             +EK             K  LI++++ LE         L +V T+  D           V
Sbjct: 320  DNEKQNNKKMIQDLNKEKTDLISKIEKLEMDNKEMNSKLNNVNTSYNDLDAKNQNNQTKV 379

Query: 476  NEIAKVQEQLKQELN-------------DEIKDVNVKDLIE-------KLKSAEEQITQL 515
            N + K+ E+L +E               DE+++ N KDLI        K +S + +I QL
Sbjct: 380  NNLEKIIEKLIKENTELANNNKNNNSKIDELQNQN-KDLISASNDMNTKNQSLQTKIDQL 438

Query: 516  N---DEIDAANK----NMIKVKSNHKLKLKQMQKTIDNFSKVSDS-NKEIVRLTEELHHL 567
            N    E++  NK    N+  +KS+   K ++  K  +N  K+ D    E   L+  L + 
Sbjct: 439  NKEKTELEEKNKVLKSNLEGLKSDLLSKNQESTKKNENLQKIIDQLQNENKLLSSNLENQ 498

Query: 568  SQKVAELEEEKGNLQLHLVDYD-SGRMIESDV---YKKMIEMEN----LAETRLKAISLL 619
            ++   +L +EK +LQ  + + + + + + S++   +K + E+ N    L     +  S L
Sbjct: 499  TKLNDDLNKEKSDLQSKIEELEKNNKDLTSNLENNHKTIEELSNKINDLQNNNKELTSNL 558

Query: 620  ESQ---KFDLVQELHILQQKYDEVEDKLADI-SQLQSDQVCSEIKSVHLEEQIDALSASK 675
            E Q     DL +E   LQ K +E+  K  ++ S  ++++   + K    E+ ID L   +
Sbjct: 559  EDQNKLNDDLNKEKADLQSKIEELSTKNEELESSNKNEKENLQNKVDEFEKIIDQL---R 615

Query: 676  KELALVIENLKLDKEQL---YGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKI 732
            KE  ++ EN K+ K  +   Y  I++L N+K D+ +K+    + N DLT  LE  + EK 
Sbjct: 616  KEKEVLEENEKVSKTNIDDDYKVIEELNNEKSDLQSKIDQLEKNNKDLTTNLELSNKEK- 674

Query: 733  SELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDR- 791
            S+L  + N  ++ +I     ++ K       ++    EL K   ++ + +E ++   ++ 
Sbjct: 675  SDLSLE-NENKRKEIDELKSLNNKTNNDIEKLQLQIQELEKSNEQLQKEKEVLSSENNQL 733

Query: 792  RYSLERKADQLGSYLQEKQKAYSEYTIQE-DELVNRLAVLMDHDRVVEKQLLEIEHENKE 850
            + ++E    ++G  +  K+KA  +  ++E D     LA  +++   + K L    +EN +
Sbjct: 734  KSNVENSEKEIG--ILNKEKADLQSKVEELDNNNKELASNLENQNKLNKVL---NNENSD 788

Query: 851  LQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRI 910
            LQ K + L  +NQ L+ S  +       L  + N  +    E  K    L    ++L+  
Sbjct: 789  LQSKIEELTTKNQELESSNIETNNEKENLQARINELEKIIDELQKENENLETESNHLRTD 848

Query: 911  THEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNN 970
               ++  I    K+  DL  +   ++E   ++   L +K   + +    L+ +  E ++ 
Sbjct: 849  LQNNEKTIADLNKDKNDLTSKIG-ELEKNNKEFTTLIDKINASNK---DLQTKNDELQSK 904

Query: 971  IENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQ 1030
            ++ L   +++LNK   +LI K +++ QT S D  +Q    +NK N  L+ K EE++  N 
Sbjct: 905  VDLLEKILDQLNKDKSDLITK-LEELQT-SIDQMKQTNENLNKENKDLQNKIEELLEEND 962

Query: 1031 KINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSK---QLLDSK-QHNEELQILVR 1086
            K NN   S    +     +LA+    L+N  EE ++ +K   +++D     NE+L     
Sbjct: 963  KANNENESKNKELQQIIDQLAEEKLSLQNKFEESEKNAKDNQKIIDELIAENEKLTSSNN 1022

Query: 1087 EQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQE 1146
            E+  +++ LK +    + N  K     +S  IE + ++ N++                Q 
Sbjct: 1023 EEKVELESLKNSLEETKQNDDKLVEE-LSKEIEKLKNENNSI----LENSDSKNNENQQI 1077

Query: 1147 EEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQ--EQINQLKSKLE 1204
             ++  +E+S L  Q  KL T+  E   K+IQ + +N +    +   Q  +Q N+LKS++E
Sbjct: 1078 IDQLKKEKSDLMNQVDKL-TKKNEDQEKVIQ-DLINDQNQKDEENKQMNDQSNELKSQIE 1135

Query: 1205 QLNTENDNLLSTVAELRSSISSAVDQRGF---EIAELWKQHLAQREAD---FQKTEHE-- 1256
            +++ EN+ L S + + + S    + +R     E+ EL K     ++ D     K  +E  
Sbjct: 1136 KISIENETLKSDLQKNKESNGELMKEREISQSELEELKKLLEETKQNDNKLIDKLRNENQ 1195

Query: 1257 -LRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYAD 1315
             L  QL      ++Q++D     T+EE++ +  +E++ +L N+L     +++NL++  ++
Sbjct: 1196 SLNNQLDMNNKDHQQIIDQF---TKEESDLMSQIEELNALNNEL---NVNIQNLEQDKSN 1249

Query: 1316 VINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENA 1375
            +  Q E L + + + K+                   L++E +  ++  +     + ++  
Sbjct: 1250 LTKQNEELNALLNETKLQ-NQNLSNENETLRSNNERLQSELKQNEEKSKSDFDQLTKDLE 1308

Query: 1376 QLKKSSXXXXXXXXXXXXRVNDAEAKV-------LELTHQLELKDSEIYQKTHEYTITLT 1428
             LK               + ND E  +        ++T  L  +D +I Q   E +  ++
Sbjct: 1309 TLKSEQSNKDKMIDELQNKTNDLEESIGKLNEEKAKITDSLTDRDQKIEQLNKEKSDLIS 1368

Query: 1429 QRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLI 1488
              N+ FE  +++L +    +     +   E   L+ ++    N   ++Q  +   + K I
Sbjct: 1369 DINN-FEASQKELNDKIDSLNSANKDLNQENEKLKSQISSLENENSSLQSANN-SKDKEI 1426

Query: 1489 EELNVKITESVSLNKQVAELNKALEEEVA-KTNEMQTALENQEIEIVTLNDEITNLQNMV 1547
            + +N +++E++S        +++  E ++ K N ++   +  E E+  L +E+  LQN +
Sbjct: 1427 KSINQQLSETISSFDNYKSQHESEAEALSNKLNNLEANKDKSEKELEELRNELEKLQNEI 1486

Query: 1548 RASSSKIQKHVSFASD-----TKQGRDEQLDNTMNKELLD 1582
            +    + +K +S  ++      ++ + E  D  MN E LD
Sbjct: 1487 QIREQR-EKELSNQNEELMNILEKMKSELNDVNMNNEQLD 1525



 Score =  191 bits (466), Expect = 1e-46
 Identities = 326/1585 (20%), Positives = 680/1585 (42%), Gaps = 163/1585 (10%)

Query: 140  QLGD-VTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXX 198
            +L D +  L++  K+ +     L+ ++  +E     LQ   N KD+ I++ N+  +    
Sbjct: 1379 ELNDKIDSLNSANKDLNQENEKLKSQISSLENENSSLQSANNSKDKEIKSINQQLSETIS 1438

Query: 199  XXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKD---EKQRLLKDIESKDVRISSL-- 253
                         E    ++  ++ N    E E ++   E ++L  +I+ ++ R   L  
Sbjct: 1439 SFDNYKSQHESEAEALSNKLNNLEANKDKSEKELEELRNELEKLQNEIQIREQREKELSN 1498

Query: 254  --EEANKLLEAARFE---ISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQ---SIEPSCE 305
              EE   +LE  + E   +++ + +L QE E               L  +    IE   +
Sbjct: 1499 QNEELMNILEKMKSELNDVNMNNEQLDQEKEILKKSLEENQQNYDQLIDELSKEIEVLKK 1558

Query: 306  EKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSP--- 362
            +    +   +     + EL  KI+ L   N  ++ TN EL+  L  +   ++ ++S    
Sbjct: 1559 QLLTKDADSNSSKHEIDELQSKIQNLSSENENLKSTNNELKQNLDDILKNNEQINSELTE 1618

Query: 363  -SKKGSPLISR-KSGRNTASKMKSPWSQLSSETLNQDTDKKINK----NEIAKL----EM 412
              +    L+S+ +S +    + K    QL  E      + K  +    N I KL    E 
Sbjct: 1619 TKQTNKDLLSQIESLKKVLEENKQNDEQLVDELSKAPDEMKHEQQKKDNRIDKLTKEKET 1678

Query: 413  VIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQ-HMEGPSLIH---- 467
            +  +LN    D + +I E +              +L  +L   + + + +   LI     
Sbjct: 1679 LHNTLNSHDKDHQQIIEEMNKEKSELESELEKLKSLNKELNENNTKLNQDKSELIKQNED 1738

Query: 468  -----------VGTNTEDVNEIAKVQEQLKQEL-NDEIKDVNVKDLIEKLKSAEEQITQL 515
                       +  N   ++E++ +   LK +L N   ++ ++K  IEK K   E+   L
Sbjct: 1739 LTNDNNHKDEFINENQVKIDELSSLLNDLKSQLQNLSNENDSLKQEIEKQKETNEK---L 1795

Query: 516  NDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDS-NKEIVRLTEELHHLSQKVAEL 574
              E++ + +N+ K KS      K +++T  N  ++ D   KEI +L  E     QK+ EL
Sbjct: 1796 QSELEDSKENLEKSKSEIDPIQKSLEETKQNDEQLVDELTKEIEKLKNEQMTKDQKIDEL 1855

Query: 575  EEEKGNLQLHLVDY--DSGRMIE------SDVYKKMIEMENLAETRLKAISLLESQKFDL 626
             +E  +L   L D   ++ ++I+      SD   K+ E++      +  I  L  +  +L
Sbjct: 1856 TKENQSLNSSLEDNNKENDQIIDQLNKEKSDYESKLNELKQDHSDLMDQIESLAKKNDEL 1915

Query: 627  VQELH----ILQQKYDEVEDKLA---------DISQLQSDQVCSEIKSVHLEEQIDALSA 673
            ++E +    I+      +E+ ++         ++   +++ + SEI+  H  E I+ L  
Sbjct: 1916 IKENNNKDQIINDNNQRIEELVSLSNKLKPQIEVLSKENESLKSEIQRNH--ENIEKLQQ 1973

Query: 674  SKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKIS 733
               E     EN   + + L   +++  N+   +MN  +N   E  D    ++++  EK +
Sbjct: 1974 KLDESQQTNENSSNEIDNLKKLLEEANNNHNQLMNDFENLKHEISDKDKMIQEL--EKRN 2031

Query: 734  ELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDR-- 791
            +     N +  +K++     +AKI E D  IE  + EL K       L+E++  ME++  
Sbjct: 2032 DANNNQNSDLSAKLKES---EAKISELDSQIEKYKQELEKLMKMNNELKETVQEMENQIQ 2088

Query: 792  -----RYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLA----VLMDHDRVVEKQLL 842
                   +L+ + D+      + Q   +E     + L++++     +L ++D   EK   
Sbjct: 2089 NISNENVNLKTEVDKSKENSNKLQNDLNEAKQNNENLLSQIESLKKLLEENDANFEKMKS 2148

Query: 843  EIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANR----------TDLAESE 892
            E+       +  +Q    EN+ L+ SL + QQ+Y+ LV++ ++          T   ES 
Sbjct: 2149 ELNDAKMNKEHSDQ----ENETLKKSLEENQQNYDQLVDELSKEIEELKKQLLTKAEESN 2204

Query: 893  STKYQTQLRDLESNLKRITHEHQTLIV---QKKKEIEDLEIEFNTQIESAIRDKKVLNEK 949
            S+K++  + +L+S ++ ++ E++ L     + K+ ++D+ ++ N QI S + + K  N+ 
Sbjct: 2205 SSKHE--IDELQSKIQNLSSENENLKSTNNELKQNLDDI-LKNNEQINSELTETKQTNKD 2261

Query: 950  YEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQ-KQQTQSPDYTEQYI 1008
                IE    L+  L+E K N E L   V+EL+K   E+  KH Q K+  +  + T++  
Sbjct: 2262 LLSQIE---SLKKVLEENKQNDEQL---VDELSKAPDEM--KHEQQKKDNRIDELTKEKE 2313

Query: 1009 NEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVS 1068
               N LN+    KD + I   +++N  +    S + +YES+L +  +  + + E   +++
Sbjct: 2314 TLYNTLNS--HDKDHQQII--EEMNKEKSELGSQIHEYESELDKLKSLNKELNENNTKLN 2369

Query: 1069 KQLLDSKQHNEEL----QILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDD 1124
            +   +  + NE+L      L+  Q+D+ + + E K   +  +P     +  S ++ +S++
Sbjct: 2370 QDKSELIKQNEDLTRNNNDLINAQNDKDRIINENKAKID-ELPSLLNDL-QSHLQNLSNE 2427

Query: 1125 ANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQ--EQSAKLNTELQECYTKIIQL---E 1179
             N++              K  EE+  I+   + +  E++ + + +L +  TK I+    E
Sbjct: 2428 NNSLKQEVEKLQTELGDSKQNEEKSKIESEQMKKSLEETKQNDEQLVDELTKEIEKLKNE 2487

Query: 1180 TLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAEL- 1238
             LN + T  ++ N+ +   +   L+  N E + ++  + +  S   S ++    ++ EL 
Sbjct: 2488 QLNKDRTIQNLTNKNE--SINKNLDSNNKEYEQIIDQLNQDLSESKSKLNDYETKMNELN 2545

Query: 1239 -WKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQN 1297
               + L +     ++ + +L  Q+     K E L++ +Q +      K   ++Q+    N
Sbjct: 2546 LLNKELQKDNETLKENQSDLINQIEELSKKNENLIN-LQGTNSNLVLKNDELQQLIDKLN 2604

Query: 1298 K-----LQDKEEHLRN---LQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXX 1349
            K     +Q+ E   +N     EK   +   IE +++   ++                   
Sbjct: 2605 KEKSDLIQENERLTKNNGESNEKLQSLDQMIETVKNNSSEKDKENHQIIDQLNKEKLDLS 2664

Query: 1350 XDLRT-ENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQ 1408
              L+  ENQ    + + S+  +N++N +L+  +            +++  E++   L   
Sbjct: 2665 SKLKDYENQL--DVLKSSLKELNDKNKELQNGNDILKQENETLTPKISSLESENSSLKST 2722

Query: 1409 LELKDSEIY---QKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKE---SELAIL 1462
             E+KD EI    QK  E +   +Q   + ++ R+Q   +EK +E+L  + E   +E+ I 
Sbjct: 2723 NEIKDKEIEELKQKLSEISQLNSQHESDLDSRRKQ---FEKELEELRNQLEKLQNEIQIR 2779

Query: 1463 RLKMHENANHYETMQK-----ESEIERVKLIEELNVKITESV--SLNKQVAELNKALEEE 1515
              +  E +N  E +       +SE+   K+ +E + +  E++  SL +     ++ ++E 
Sbjct: 2780 EQRGKELSNQNEELMNNLEKMKSELNDAKMNKEHSDQENETLKKSLEENQQNYDQLVDEL 2839

Query: 1516 VAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNT 1575
              +  E++  L  +  E  +   EI  LQ+ ++  SS+ +   S  ++ KQ  +   ++ 
Sbjct: 2840 SKEIEELKKQLLTKAEESNSSKHEIDELQSKIQNLSSENENLKSTNNELKQQIESLKNDL 2899

Query: 1576 MNKELLDAVPRAELDLAMYMLHQRD 1600
             NK+ +      E+D +    H+ +
Sbjct: 2900 QNKDQIVEELTKEIDSSNKQSHENN 2924



 Score =  180 bits (437), Expect = 4e-43
 Identities = 323/1539 (20%), Positives = 641/1539 (41%), Gaps = 146/1539 (9%)

Query: 158  LSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQ 217
            L  L+ +    +  I +LQ K N+ ++ I   N+                    ++ K  
Sbjct: 1307 LETLKSEQSNKDKMIDELQNKTNDLEESIGKLNEEKAKITDSLTDRDQKIEQLNKE-KSD 1365

Query: 218  MTKMQENFIAMEAEWKDEKQRLL---KDIESKDVR----ISSLEEANKLLEAARFEISLE 270
            +     NF A + E  D+   L    KD+  ++ +    ISSLE  N  L++A      E
Sbjct: 1366 LISDINNFEASQKELNDKIDSLNSANKDLNQENEKLKSQISSLENENSSLQSANNSKDKE 1425

Query: 271  HSKLAQELEQXXXXXXXXXXXXXXLAKQSIEP--SCEEKTEIEEKGSLEIANMTE-LTKK 327
               + Q+L +               A+       + E   +  EK   E+ N  E L  +
Sbjct: 1426 IKSINQQLSETISSFDNYKSQHESEAEALSNKLNNLEANKDKSEKELEELRNELEKLQNE 1485

Query: 328  IELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKK--GSPLISRKSGRNTASKMKSP 385
            I++ E    ++   N+EL N L  M +E   V+  +++      I +KS           
Sbjct: 1486 IQIREQREKELSNQNEELMNILEKMKSELNDVNMNNEQLDQEKEILKKSLEENQQNYDQL 1545

Query: 386  WSQLSSET-------LNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXX 438
              +LS E        L +D D   +K+EI +L+  IQ+L+ +    E + S  +      
Sbjct: 1546 IDELSKEIEVLKKQLLTKDADSNSSKHEIDELQSKIQNLSSE---NENLKSTNNELKQNL 1602

Query: 439  XXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELN---DEIKD 495
                   + + ++L    Q + +   L  + +  + + E  +  EQL  EL+   DE+K 
Sbjct: 1603 DDILKNNEQINSELTETKQTNKD--LLSQIESLKKVLEENKQNDEQLVDELSKAPDEMKH 1660

Query: 496  VNVK--DLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKL-------KLKQMQKTI-D 545
               K  + I+KL   +E +    +  D  ++ +I+  +  K        KLK + K + +
Sbjct: 1661 EQQKKDNRIDKLTKEKETLHNTLNSHDKDHQQIIEEMNKEKSELESELEKLKSLNKELNE 1720

Query: 546  NFSKVSDSNKEIVRLTEEL----HHLSQKVAELEEEKGNLQLHLVDYDS---GRMIESDV 598
            N +K++    E+++  E+L    +H  + + E + +   L   L D  S       E+D 
Sbjct: 1721 NNTKLNQDKSELIKQNEDLTNDNNHKDEFINENQVKIDELSSLLNDLKSQLQNLSNENDS 1780

Query: 599  YKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSE 658
             K+ IE +   ET  K  S LE  K +L +    +      +E+   +  QL  D++  E
Sbjct: 1781 LKQEIEKQK--ETNEKLQSELEDSKENLEKSKSEIDPIQKSLEETKQNDEQLV-DELTKE 1837

Query: 659  IKSVHLEE-----QIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNY 713
            I+ +  E+     +ID L+   + L   +E+   + +Q+   I  L  +K D  +KL   
Sbjct: 1838 IEKLKNEQMTKDQKIDELTKENQSLNSSLEDNNKENDQI---IDQLNKEKSDYESKLNEL 1894

Query: 714  IQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSK 773
             Q++ DL D++E + A+K  EL+ + N+++Q            I + +  IE + S  +K
Sbjct: 1895 KQDHSDLMDQIESL-AKKNDELIKENNNKDQI-----------INDNNQRIEELVSLSNK 1942

Query: 774  YKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDH 833
             K +I  L +    ++          ++L   L E Q+     + + D L   L    ++
Sbjct: 1943 LKPQIEVLSKENESLKSEIQRNHENIEKLQQKLDESQQTNENSSNEIDNLKKLLEEANNN 2002

Query: 834  DRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESES 893
               +      ++HE  +  K  Q L + N       SD+      L E   +    +S+ 
Sbjct: 2003 HNQLMNDFENLKHEISDKDKMIQELEKRNDANNNQNSDLSA---KLKESEAKISELDSQI 2059

Query: 894  TKYQTQLRDL---ESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKY 950
             KY+ +L  L    + LK    E +  I     E  +L+ E +   E++ + +  LNE  
Sbjct: 2060 EKYKQELEKLMKMNNELKETVQEMENQIQNISNENVNLKTEVDKSKENSNKLQNDLNEAK 2119

Query: 951  EKNIEYVTQLEAQLQEYKNNIENLNMNVEELN--KMNLELIDKHVQKQQTQSPDYTEQYI 1008
            + N   ++Q+E+  +  + N  N      ELN  KMN E  D+  +  +    +  + Y 
Sbjct: 2120 QNNENLLSQIESLKKLLEENDANFEKMKSELNDAKMNKEHSDQENETLKKSLEENQQNYD 2179

Query: 1009 NEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENME----EEM 1064
              +++L+  +++  ++++   ++ N+++      + + +SK+   +++ EN++    E  
Sbjct: 2180 QLVDELSKEIEELKKQLLTKAEESNSSK----HEIDELQSKIQNLSSENENLKSTNNELK 2235

Query: 1065 QRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMI--ISSTIEPMS 1122
            Q +   L +++Q N EL    +   D + +++  K   E N    E ++  +S   + M 
Sbjct: 2236 QNLDDILKNNEQINSELTETKQTNKDLLSQIESLKKVLEENKQNDEQLVDELSKAPDEMK 2295

Query: 1123 DDA----NNVDXXXXXXXXXXXXLKVQEE------EEFIQERSVLQEQ----------SA 1162
             +     N +D            L   ++      EE  +E+S L  Q            
Sbjct: 2296 HEQQKKDNRIDELTKEKETLYNTLNSHDKDHQQIIEEMNKEKSELGSQIHEYESELDKLK 2355

Query: 1163 KLNTELQECYTKIIQ----LETLNTELT--GHDVVNQEQ-----INQLKSKLEQLNTEND 1211
             LN EL E  TK+ Q    L   N +LT   +D++N +      IN+ K+K+++L +  +
Sbjct: 2356 SLNKELNENNTKLNQDKSELIKQNEDLTRNNNDLINAQNDKDRIINENKAKIDELPSLLN 2415

Query: 1212 NLLSTVAEL---RSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKY 1268
            +L S +  L    +S+   V++   E+ +  KQ+  + + + ++ +  L       E   
Sbjct: 2416 DLQSHLQNLSNENNSLKQEVEKLQTELGDS-KQNEEKSKIESEQMKKSLEETKQNDEQLV 2474

Query: 1269 EQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIE 1328
            ++L   ++    E+ NK  T++ +T   NK +   ++L +  ++Y  +I+Q+    SE +
Sbjct: 2475 DELTKEIEKLKNEQLNKDRTIQNLT---NKNESINKNLDSNNKEYEQIIDQLNQDLSESK 2531

Query: 1329 DEKVAFXXXXXXXXXXXXXXXXDLRT--ENQS--YKQMQEQSILNINEENAQLKKSS-XX 1383
             +   +                D  T  ENQS    Q++E S  N N  N Q   S+   
Sbjct: 2532 SKLNDYETKMNELNLLNKELQKDNETLKENQSDLINQIEELSKKNENLINLQGTNSNLVL 2591

Query: 1384 XXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTH---EYTITLTQRNDEFENVRQQ 1440
                      ++N  ++ +++   +L   + E  +K     +   T+   + E +    Q
Sbjct: 2592 KNDELQQLIDKLNKEKSDLIQENERLTKNNGESNEKLQSLDQMIETVKNNSSEKDKENHQ 2651

Query: 1441 LV-EYEKRIEDLT---YEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKIT 1496
            ++ +  K   DL+    + E++L +L+  + E  +  + +Q  ++I + +  E L  KI+
Sbjct: 2652 IIDQLNKEKLDLSSKLKDYENQLDVLKSSLKELNDKNKELQNGNDILKQE-NETLTPKIS 2710

Query: 1497 ESVSLNKQVAELN----KALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSS 1552
               S N  +   N    K +EE   K +E+       E ++ +   +       +R    
Sbjct: 2711 SLESENSSLKSTNEIKDKEIEELKQKLSEISQLNSQHESDLDSRRKQFEKELEELRNQLE 2770

Query: 1553 KIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDL 1591
            K+Q  +      ++ R ++L N  N+EL++ + + + +L
Sbjct: 2771 KLQNEIQI----REQRGKELSN-QNEELMNNLEKMKSEL 2804



 Score =  174 bits (424), Expect = 1e-41
 Identities = 306/1501 (20%), Positives = 628/1501 (41%), Gaps = 161/1501 (10%)

Query: 147  LSNTIKEKDNALSVLQVKMKIMETTILDLQEKI----NEKDQIIEAKNKATTXXXXXXXX 202
            L N   +KD  ++  + K+  + + + DLQ  +    NE + + +   K  T        
Sbjct: 2389 LINAQNDKDRIINENKAKIDELPSLLNDLQSHLQNLSNENNSLKQEVEKLQTELGDSKQN 2448

Query: 203  XXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSL----EEANK 258
                     E  K+ + + ++N   +  E   E ++L  +  +KD  I +L    E  NK
Sbjct: 2449 EEKSKIES-EQMKKSLEETKQNDEQLVDELTKEIEKLKNEQLNKDRTIQNLTNKNESINK 2507

Query: 259  LLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEI 318
             L++   E      +L Q+L +              L   + E   + +T  E +  L I
Sbjct: 2508 NLDSNNKEYEQIIDQLNQDLSESKSKLNDYETKMNELNLLNKELQKDNETLKENQSDL-I 2566

Query: 319  ANMTELTKKIELLEHL---NCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSG 375
              + EL+KK E L +L   N  +   N EL+  +  +  E   +   +++    +++ +G
Sbjct: 2567 NQIEELSKKNENLINLQGTNSNLVLKNDELQQLIDKLNKEKSDLIQENER----LTKNNG 2622

Query: 376  RNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXX 435
             +   K++S    +  ET+  ++ +K  +N       +I  LNK+ +D    + + +   
Sbjct: 2623 ESN-EKLQSLDQMI--ETVKNNSSEKDKENH-----QIIDQLNKEKLDLSSKLKDYENQL 2674

Query: 436  XXXXXXXXGKDTLIAQLQ-----LEHQQHMEGP---SLIHVGTNTEDVNEIA-KVQEQLK 486
                      +    +LQ     L+ +     P   SL    ++ +  NEI  K  E+LK
Sbjct: 2675 DVLKSSLKELNDKNKELQNGNDILKQENETLTPKISSLESENSSLKSTNEIKDKEIEELK 2734

Query: 487  QELND--EIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLK-QMQKT 543
            Q+L++  ++   +  DL  + K  E+++ +L ++++   +N I+++     +L  Q ++ 
Sbjct: 2735 QKLSEISQLNSQHESDLDSRRKQFEKELEELRNQLEKL-QNEIQIREQRGKELSNQNEEL 2793

Query: 544  IDNFSKV-------------SDSNKEIVR--LTEELHHLSQKVAELEEEKGNLQLHLV-- 586
            ++N  K+             SD   E ++  L E   +  Q V EL +E   L+  L+  
Sbjct: 2794 MNNLEKMKSELNDAKMNKEHSDQENETLKKSLEENQQNYDQLVDELSKEIEELKKQLLTK 2853

Query: 587  --DYDSGRM----IESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEV 640
              + +S +     ++S +     E ENL  T  +    +ES K DL  +  I+++   E+
Sbjct: 2854 AEESNSSKHEIDELQSKIQNLSSENENLKSTNNELKQQIESLKNDLQNKDQIVEELTKEI 2913

Query: 641  EDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELAL-------VIENLKLDKEQLY 693
            +   ++    +++++ ++ K + L +QI+ L+  + E+         +I +LK+  E+L 
Sbjct: 2914 DS--SNKQSHENNELLNQ-KQLDLMKQIEDLTKKQGEMLKQNQNQENIINDLKIKNEELT 2970

Query: 694  --GTIKD-----LENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQS- 745
              G  KD     L     D  + +QN   EN  L   L+       ++L  K+N  +Q+ 
Sbjct: 2971 KEGNNKDKVINELNKSLNDFKSLIQNLSNENEKLKSALQNSQGNN-ADLQQKLNSTQQND 3029

Query: 746  -KIQTQFGIDAK-IQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLG 803
              +  Q  +  K +QE     +N+ +E+   K      ++ I  +  +   L  K  Q+ 
Sbjct: 3030 QNLLNQIELLKKSLQENKQNEDNLVNEIQNQKIENQNKDQIIEDLRKKNEELNLKQQQIQ 3089

Query: 804  SYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQ 863
                 K+K+     +Q   L      L+ ++  +E++  ++ ++  +L+KKN+IL ++  
Sbjct: 3090 DQFN-KEKSGLISKLQGLNLSGN--ELLSNNEKLEQEQSDLMNQINDLRKKNEILNQQQA 3146

Query: 864  NLQISLSDMQQHYNALVEKAN----RTDLAESESTKYQTQLRDLESNLKRITHEHQTLIV 919
            N    + + Q+      E  N    + + A + +   + Q+  L+  L+        L+ 
Sbjct: 3147 NNNQIIKECQEKIQNYEESNNELQRKLNEAMNNNENAKNQIDQLKKLLEETKQNDDKLVE 3206

Query: 920  QKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVE 979
            +  KEIE L+ E  ++ ++ I D   LN+     I+    L  + QE+ N+ +N    +E
Sbjct: 3207 ELTKEIEKLKNEQQSKDQN-INDLSALNKDKSSLIQQNDDLSKKTQEFYNSQQNQAQMIE 3265

Query: 980  ELNKMN------LELIDKHVQ-------KQQTQSPDYTEQYINEINKLNALLKQKDEEII 1026
            +L K N      LE+ +   Q       K ++        Y  +IN LN+L+K+ +E+  
Sbjct: 3266 DLKKQNESLQKNLEINNNETQQNIDQLTKDKSDLASKLHDYEAKINDLNSLIKELNEKN- 3324

Query: 1027 ALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVR 1086
            A+ +K N      + + +D  SK  Q    ++ + ++   +SKQ+ D    N E+   + 
Sbjct: 3325 AIIEKKNYEFSQQLEVNNDLISKNNQLQQTIDQLNKDKTVLSKQIQDLANKNNEITNQLN 3384

Query: 1087 EQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQE 1146
             +D  I E K+   + E+N   +  M    T++  +DD N+              L++++
Sbjct: 3385 NKDKIILESKQK--SDELNQSLSNLMKELHTLKANNDDLNS-QISQSKQNEENLQLQIEK 3441

Query: 1147 EEEFIQE-----RSVLQEQSAKLNTELQEC-------------YTKII-QLETLNTELTG 1187
            +++ +Q+       ++ + S ++ T   E              Y+ I+ QL+  N E+  
Sbjct: 3442 QKKLLQDTKQNDNKLVDDLSKEVETLTSEKLKNEEIIKQNNAKYSGILKQLQQKNEEINK 3501

Query: 1188 ------HDVVNQEQ--------INQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGF 1233
                  HD+  ++Q        +NQ K KL Q N +  + L    +    I++   Q+  
Sbjct: 3502 EKEQFKHDLEGEKQKNEKLVNDLNQTKDKLSQENEKLKHYLVAFKQNNEQITADNKQKDE 3561

Query: 1234 EIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVT 1293
             I +L KQ +   ++  Q+ E +L+ Q +  +  Y+ L++ +    +  T+   ++ +  
Sbjct: 3562 NIQQLMKQ-INSLKSQLQEDE-KLKSQFAKMKENYDSLINKLNQENKSLTH---SLNESL 3616

Query: 1294 SLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLR 1353
                +L    E L+   E  ++ +NQ+    +  + E                     L 
Sbjct: 3617 KHNEELSKNNEKLQQNNELLSNKLNQLGSQDNNKQKEIENMNQKLQKVSNEGKQKEDQLI 3676

Query: 1354 TENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKD 1413
             E  + K     S++ +  +N  + +              + N+ +    EL +  + K+
Sbjct: 3677 EEINNLKF----SLIELQRKNEDMNQMLSETKKQNEVLSEQNNEIQLLKNELENLSKSKE 3732

Query: 1414 SEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHY 1473
             EI     EY   + ++ DE E++ +     +K+ E  +YEK         K  E    Y
Sbjct: 3733 DEINSLKEEYERKIKEKEDEIEHLEENCNNEKKKTE--SYEK---------KFVEEKGEY 3781

Query: 1474 ETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEI 1533
            E+ Q+ +E    +L  E+ + + E+  L+K   + + A++ E  K  E    L+ +    
Sbjct: 3782 ESKQQNTETYIEELETEIELLLKENEQLDKTKYDYD-AIQHEYNKVREDLAKLQKEHDNF 3840

Query: 1534 V 1534
            V
Sbjct: 3841 V 3841



 Score =  173 bits (422), Expect = 3e-41
 Identities = 243/1184 (20%), Positives = 521/1184 (44%), Gaps = 98/1184 (8%)

Query: 472  TEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKS 531
            ++D  +++K  EQL QE      + ++  L+   KS   ++    +++ +ANK +     
Sbjct: 211  SKDNEKLSKENEQLNQE------NTSLSTLLGSAKSTNLELENTIEQLKSANKELSDKNV 264

Query: 532  NHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSG 591
              + KL  +QK  +  +  +D      +L  E  +L +++ EL      L +  ++    
Sbjct: 265  EIQAKLINLQKEKEQLTSTND------KLLTETENLKKEIDELNNANKELNVKSINLQQS 318

Query: 592  RMIESDVYKKMIEMENLAETRL-KAISLLESQKFDLVQELHILQQKYDEVEDKLADISQL 650
               E    KKMI+  N  +T L   I  LE    ++  +L+ +   Y++++ K  + +Q 
Sbjct: 319  LDNEKQNNKKMIQDLNKEKTDLISKIEKLEMDNKEMNSKLNNVNTSYNDLDAKNQN-NQT 377

Query: 651  QSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKL 710
            + + +   I+ + ++E  + L+ + K     I+ L+   + L     D+    + +  K+
Sbjct: 378  KVNNLEKIIEKL-IKENTE-LANNNKNNNSKIDELQNQNKDLISASNDMNTKNQSLQTKI 435

Query: 711  QNYIQENMDLTDKLE--KMSAEKI-SELLAKINHEEQSKIQTQFGIDAKIQERDLYIENI 767
                +E  +L +K +  K + E + S+LL+K     +     Q  ID    E  L   N+
Sbjct: 436  DQLNKEKTELEEKNKVLKSNLEGLKSDLLSKNQESTKKNENLQKIIDQLQNENKLLSSNL 495

Query: 768  ESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNR- 826
            E++          L +  + ++ +   LE+    L S L+   K   E + + ++L N  
Sbjct: 496  ENQTKLNDD----LNKEKSDLQSKIEELEKNNKDLTSNLENNHKTIEELSNKINDLQNNN 551

Query: 827  ---LAVLMDHDRV---VEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALV 880
                + L D +++   + K+  +++ + +EL  KN+ L   N+N + +L +    +  ++
Sbjct: 552  KELTSNLEDQNKLNDDLNKEKADLQSKIEELSTKNEELESSNKNEKENLQNKVDEFEKII 611

Query: 881  EKANRTDLAESESTKY-QTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESA 939
            ++  +      E+ K  +T + D    ++ + +E   L   K  ++E    +  T +E +
Sbjct: 612  DQLRKEKEVLEENEKVSKTNIDDDYKVIEELNNEKSDL-QSKIDQLEKNNKDLTTNLELS 670

Query: 940  IRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELI-DKHV----Q 994
             ++K  L+ + E   + + +L++   +  N+IE L + ++EL K N +L  +K V     
Sbjct: 671  NKEKSDLSLENENKRKEIDELKSLNNKTNNDIEKLQLQIQELEKSNEQLQKEKEVLSSEN 730

Query: 995  KQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFT 1054
             Q   + + +E+ I  +NK  A L+ K EE+   N+++ +   +   +     ++ +   
Sbjct: 731  NQLKSNVENSEKEIGILNKEKADLQSKVEELDNNNKELASNLENQNKLNKVLNNENSDLQ 790

Query: 1055 TKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKEL-KETK-LTFEMNIPKTEGM 1112
            +K+E +  + Q +    +++    E LQ  + E +  I EL KE + L  E N  +T+  
Sbjct: 791  SKIEELTTKNQELESSNIETNNEKENLQARINELEKIIDELQKENENLETESNHLRTDLQ 850

Query: 1113 IISSTIEPMSDDAN------------NVDXXXXXXXXXXXXLKVQEEEEFIQER-SVLQE 1159
                TI  ++ D N            N +              +Q + + +Q +  +L++
Sbjct: 851  NNEKTIADLNKDKNDLTSKIGELEKNNKEFTTLIDKINASNKDLQTKNDELQSKVDLLEK 910

Query: 1160 QSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAE 1219
               +LN +  +  TK+ +L+T   ++   +    ++   L++K+E+L  END   +    
Sbjct: 911  ILDQLNKDKSDLITKLEELQTSIDQMKQTNENLNKENKDLQNKIEELLEENDKANNENES 970

Query: 1220 LRSSISSAVDQRGFEIAELW-KQHLAQREA-DFQKTEHELRVQ---LSAFESKYEQLLDS 1274
                +   +DQ   E   L  K   +++ A D QK   EL  +   L++  ++ +  L+S
Sbjct: 971  KNKELQQIIDQLAEEKLSLQNKFEESEKNAKDNQKIIDELIAENEKLTSSNNEEKVELES 1030

Query: 1275 VQSS---TQEETNKIVT--MEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIED 1329
            +++S   T++  +K+V    +++  L+N+     E+  +   +   +I+Q++  +S++ +
Sbjct: 1031 LKNSLEETKQNDDKLVEELSKEIEKLKNENNSILENSDSKNNENQQIIDQLKKEKSDLMN 1090

Query: 1330 EKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQS------ILNINEENAQLKKSSXX 1383
            +                    D   +++  KQM +QS      I  I+ EN  LK     
Sbjct: 1091 QVDKLTKKNEDQEKVIQDLINDQNQKDEENKQMNDQSNELKSQIEKISIENETLKSDLQK 1150

Query: 1384 XXXXXXXXXXRVNDAEAKVLELTHQLE---LKDSEIYQKTHEYTITLTQRNDEFENVRQQ 1440
                          +++++ EL   LE     D+++  K      +L  + D      QQ
Sbjct: 1151 NKESNGELMKEREISQSELEELKKLLEETKQNDNKLIDKLRNENQSLNNQLDMNNKDHQQ 1210

Query: 1441 LVE-YEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESV 1499
            +++ + K   DL  + E EL  L  +++ N  + E  Q +S +   K  EELN  + E+ 
Sbjct: 1211 IIDQFTKEESDLMSQIE-ELNALNNELNVNIQNLE--QDKSNL--TKQNEELNALLNETK 1265

Query: 1500 SLNKQVAELNKALE-------------EEVAK------TNEMQTALENQEIEIVTLNDEI 1540
              N+ ++  N+ L              EE +K      T +++T L++++     + DE+
Sbjct: 1266 LQNQNLSNENETLRSNNERLQSELKQNEEKSKSDFDQLTKDLET-LKSEQSNKDKMIDEL 1324

Query: 1541 TNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAV 1584
             N  N +  S  K+ +  +  +D+   RD++++  +NKE  D +
Sbjct: 1325 QNKTNDLEESIGKLNEEKAKITDSLTDRDQKIEQ-LNKEKSDLI 1367



 Score =  169 bits (412), Expect = 4e-40
 Identities = 304/1466 (20%), Positives = 620/1466 (42%), Gaps = 129/1466 (8%)

Query: 174  DLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWK 233
            DL    N+KD+II  +NKA                   ++   +   +++    ++ E  
Sbjct: 2388 DLINAQNDKDRIIN-ENKAKIDELPSLLNDLQSHL---QNLSNENNSLKQEVEKLQTELG 2443

Query: 234  DEKQRLLKD-IESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXX 292
            D KQ   K  IES+ ++  SLEE  +  E    E++ E  KL  E               
Sbjct: 2444 DSKQNEEKSKIESEQMK-KSLEETKQNDEQLVDELTKEIEKLKNEQLNKDRTIQNLTNKN 2502

Query: 293  XXLAKQSIEPSCEEKTEIEEKGSLEIAN----MTELTKKIELLEHLNCQIRQTNKELENK 348
              + K +++ + +E  +I ++ + +++     + +   K+  L  LN ++++ N+ L+  
Sbjct: 2503 ESINK-NLDSNNKEYEQIIDQLNQDLSESKSKLNDYETKMNELNLLNKELQKDNETLKEN 2561

Query: 349  LATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIA 408
             + +  +   +   SKK   LI+ + G N+   +K+   Q   + LN++    I +NE  
Sbjct: 2562 QSDLINQ---IEELSKKNENLINLQ-GTNSNLVLKNDELQQLIDKLNKEKSDLIQENE-- 2615

Query: 409  KLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHV 468
            +L       N+ L   + +I   +T              +I QL  E          + +
Sbjct: 2616 RLTKNNGESNEKLQSLDQMI---ETVKNNSSEKDKENHQIIDQLNKEK---------LDL 2663

Query: 469  GTNTEDVNEIAKVQEQLKQELNDEIKDV-NVKDLIEKLKSAEEQITQLNDEIDAANKNMI 527
             +  +D      V +   +ELND+ K++ N  D+   LK   E +T     +++ N ++ 
Sbjct: 2664 SSKLKDYENQLDVLKSSLKELNDKNKELQNGNDI---LKQENETLTPKISSLESENSSL- 2719

Query: 528  KVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVR-LTEELHHLSQKVAELEEEKGNLQLHL- 585
              KS +++K K++++     S++S  N +    L        +++ EL  +   LQ  + 
Sbjct: 2720 --KSTNEIKDKEIEELKQKLSEISQLNSQHESDLDSRRKQFEKELEELRNQLEKLQNEIQ 2777

Query: 586  VDYDSGRMIESDVYKKMIEMENLAETRLKAISLLE---SQKFDLVQELHILQQKYDEVED 642
            +    G+ + +   + M  +E +      A    E    +   L + L   QQ YD++ D
Sbjct: 2778 IREQRGKELSNQNEELMNNLEKMKSELNDAKMNKEHSDQENETLKKSLEENQQNYDQLVD 2837

Query: 643  KLA-DISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLEN 701
            +L+ +I +L+   +    +S   + +ID L +  + L+   ENLK    +L   I+ L+N
Sbjct: 2838 ELSKEIEELKKQLLTKAEESNSSKHEIDELQSKIQNLSSENENLKSTNNELKQQIESLKN 2897

Query: 702  D---KEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQ 758
            D   K+ I+ +L   I  +   + +  ++  +K  +L+ +I  E+ +K Q +     + Q
Sbjct: 2898 DLQNKDQIVEELTKEIDSSNKQSHENNELLNQKQLDLMKQI--EDLTKKQGEMLKQNQNQ 2955

Query: 759  ER---DLYIENIE--SELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAY 813
            E    DL I+N E   E +     I  L +S+   +    +L  + ++L S LQ  Q   
Sbjct: 2956 ENIINDLKIKNEELTKEGNNKDKVINELNKSLNDFKSLIQNLSNENEKLKSALQNSQGNN 3015

Query: 814  SEY------TIQEDE-LVNRLAVL---MDHDRVVEKQLL-EIEHENKELQKKNQI---LL 859
            ++       T Q D+ L+N++ +L   +  ++  E  L+ EI+++  E Q K+QI   L 
Sbjct: 3016 ADLQQKLNSTQQNDQNLLNQIELLKKSLQENKQNEDNLVNEIQNQKIENQNKDQIIEDLR 3075

Query: 860  EENQNLQISLSDMQQHYN----ALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQ 915
            ++N+ L +    +Q  +N     L+ K    +L+ +E      +L   +S+L    ++  
Sbjct: 3076 KKNEELNLKQQQIQDQFNKEKSGLISKLQGLNLSGNELLSNNEKLEQEQSDLMNQIND-- 3133

Query: 916  TLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLN 975
               ++KK EI + +   N QI    ++K    + YE   E   +L+ +L E  NN EN  
Sbjct: 3134 ---LRKKNEILNQQQANNNQIIKECQEKI---QNYE---ESNNELQRKLNEAMNNNENAK 3184

Query: 976  MNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNA 1035
              +++L K+        +++ +       E+   EI KL    + KD+ I  L+  +N  
Sbjct: 3185 NQIDQLKKL--------LEETKQNDDKLVEELTKEIEKLKNEQQSKDQNINDLSA-LNKD 3235

Query: 1036 QVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKEL 1095
            + S +    D   K  +F    +N  + ++ + KQ  +S Q N  L+I   E    I +L
Sbjct: 3236 KSSLIQQNDDLSKKTQEFYNSQQNQAQMIEDLKKQN-ESLQKN--LEINNNETQQNIDQL 3292

Query: 1096 KETKLTFEMNIPKTEGMI--ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQE 1153
             + K      +   E  I  ++S I+ +++    ++             +++   + I +
Sbjct: 3293 TKDKSDLASKLHDYEAKINDLNSLIKELNEKNAIIEKKNYEFSQ-----QLEVNNDLISK 3347

Query: 1154 RSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNL 1213
             + LQ+   +LN +      +I  L   N E+T       + I + K K ++LN    NL
Sbjct: 3348 NNQLQQTIDQLNKDKTVLSKQIQDLANKNNEITNQLNNKDKIILESKQKSDELNQSLSNL 3407

Query: 1214 LSTVA-------ELRSSIS-SAVDQRGFEIA-ELWKQHLAQREADFQKTEHELRVQLSAF 1264
            +  +        +L S IS S  ++   ++  E  K+ L   + +  K   +L  ++   
Sbjct: 3408 MKELHTLKANNDDLNSQISQSKQNEENLQLQIEKQKKLLQDTKQNDNKLVDDLSKEVETL 3467

Query: 1265 ESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEH-LRNLQEKYADVINQIEIL 1323
             S+  +  + ++ +  + +  +  ++Q     NK +++ +H L   ++K   ++N +   
Sbjct: 3468 TSEKLKNEEIIKQNNAKYSGILKQLQQKNEEINKEKEQFKHDLEGEKQKNEKLVNDLNQT 3527

Query: 1324 RSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXX 1383
            + ++  E                    D + ++++ +Q+ +Q I ++  +  + +K    
Sbjct: 3528 KDKLSQENEKLKHYLVAFKQNNEQITADNKQKDENIQQLMKQ-INSLKSQLQEDEKLKSQ 3586

Query: 1384 XXXXXXXXXXRVNDAEAKVLELTHQLE--LKDSEIYQKTHEYTITLTQRNDEFENVRQQL 1441
                       +N    +   LTH L   LK +E   K +E    L Q N+   N   QL
Sbjct: 3587 FAKMKENYDSLINKLNQENKSLTHSLNESLKHNEELSKNNE---KLQQNNELLSNKLNQL 3643

Query: 1442 VEYE----KRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITE 1497
               +    K IE++  + +      + K  +       + K S IE  +  E++N  ++E
Sbjct: 3644 GSQDNNKQKEIENMNQKLQKVSNEGKQKEDQLIEEINNL-KFSLIELQRKNEDMNQMLSE 3702

Query: 1498 SVSLNKQVAELNKALE------EEVAKT--NEMQTALENQEIEIVTLNDEITNLQNMVRA 1549
            +   N+ ++E N  ++      E ++K+  +E+ +  E  E +I    DEI +L+     
Sbjct: 3703 TKKQNEVLSEQNNEIQLLKNELENLSKSKEDEINSLKEEYERKIKEKEDEIEHLEENCNN 3762

Query: 1550 SSSKIQKHVSFASDTKQGRDEQLDNT 1575
               K + +     + K   + +  NT
Sbjct: 3763 EKKKTESYEKKFVEEKGEYESKQQNT 3788



 Score =  161 bits (392), Expect = 1e-37
 Identities = 289/1458 (19%), Positives = 613/1458 (42%), Gaps = 139/1458 (9%)

Query: 144  VTHLSNTIKEKDNALSVLQVKMKIMETTILDLQE-----KINEKDQIIEAKNKATTXXXX 198
            +  L+  + E  + L+  + KM  +     +LQ+     K N+ D I + +  +      
Sbjct: 2520 IDQLNQDLSESKSKLNDYETKMNELNLLNKELQKDNETLKENQSDLINQIEELSKKNENL 2579

Query: 199  XXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANK 258
                          D  QQ+    +     +++   E +RL K+    + ++ SL++  +
Sbjct: 2580 INLQGTNSNLVLKNDELQQLI---DKLNKEKSDLIQENERLTKNNGESNEKLQSLDQMIE 2636

Query: 259  LLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXX---LAKQSIEPSCEEKTEIEEKGS 315
             ++    E   E+ ++  +L +                 + K S++   ++  E++    
Sbjct: 2637 TVKNNSSEKDKENHQIIDQLNKEKLDLSSKLKDYENQLDVLKSSLKELNDKNKELQNGND 2696

Query: 316  LEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSS-PSKKGSPLISR-K 373
            +       LT KI  LE  N  ++ TN+  + ++  +  +   +S   S+  S L SR K
Sbjct: 2697 ILKQENETLTPKISSLESENSSLKSTNEIKDKEIEELKQKLSEISQLNSQHESDLDSRRK 2756

Query: 374  SGRNTASKMKSPWSQLSSET-LNQDTDKKI-NKNE--IAKLEMVIQSLNKDLVDKEYVIS 429
                   ++++   +L +E  + +   K++ N+NE  +  LE +   LN   ++KE+   
Sbjct: 2757 QFEKELEELRNQLEKLQNEIQIREQRGKELSNQNEELMNNLEKMKSELNDAKMNKEHSDQ 2816

Query: 430  EKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQ-- 487
            E +T            D L+ +L  E ++ ++   L     +    +EI ++Q +++   
Sbjct: 2817 ENETLKKSLEENQQNYDQLVDELSKEIEE-LKKQLLTKAEESNSSKHEIDELQSKIQNLS 2875

Query: 488  ELNDEIKDVN--VKDLIEKLKS----AEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQ 541
              N+ +K  N  +K  IE LK+     ++ + +L  EID++NK     ++N  L  KQ+ 
Sbjct: 2876 SENENLKSTNNELKQQIESLKNDLQNKDQIVEELTKEIDSSNKQ--SHENNELLNQKQLD 2933

Query: 542  --KTIDNFSKVS-DSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDV 598
              K I++ +K   +  K+       ++ L  K  EL +E GN +  +++ +  + +    
Sbjct: 2934 LMKQIEDLTKKQGEMLKQNQNQENIINDLKIKNEELTKE-GNNKDKVIN-ELNKSLND-- 2989

Query: 599  YKKMIE-MENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCS 657
            +K +I+ + N  E    A+   +    DL Q+L+  QQ    + +++  + +   +   +
Sbjct: 2990 FKSLIQNLSNENEKLKSALQNSQGNNADLQQKLNSTQQNDQNLLNQIELLKKSLQENKQN 3049

Query: 658  EIKSVHLEEQIDALSASKKELALVIENLKLDKEQL---YGTIKDLEN-DKEDIMNKLQNY 713
            E   V+ E Q   +    K+   +IE+L+   E+L      I+D  N +K  +++KLQ  
Sbjct: 3050 EDNLVN-EIQNQKIENQNKDQ--IIEDLRKKNEELNLKQQQIQDQFNKEKSGLISKLQGL 3106

Query: 714  IQENMDLTDKLEKMSAEKISELLAKINH-EEQSKIQTQFGIDAKIQERDLYIENIESELS 772
                 +L    EK+  E+ S+L+ +IN   ++++I  Q     +    +  I+  + ++ 
Sbjct: 3107 NLSGNELLSNNEKLEQEQ-SDLMNQINDLRKKNEILNQ-----QQANNNQIIKECQEKIQ 3160

Query: 773  KYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMD 832
             Y+     L+  +    +   + + + DQL   L+E ++   +     +EL   +  L +
Sbjct: 3161 NYEESNNELQRKLNEAMNNNENAKNQIDQLKKLLEETKQNDDKLV---EELTKEIEKLKN 3217

Query: 833  HDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESE 892
              +  ++ + ++   NK+       L+++N +L       Q+ YN+   +A   +  + +
Sbjct: 3218 EQQSKDQNINDLSALNKDKSS----LIQQNDDLS---KKTQEFYNSQQNQAQMIEDLKKQ 3270

Query: 893  STKYQTQLR----DLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNE 948
            +   Q  L     + + N+ ++T +   L   K  + E    + N+ I+  + +K  + E
Sbjct: 3271 NESLQKNLEINNNETQQNIDQLTKDKSDL-ASKLHDYEAKINDLNSLIKE-LNEKNAIIE 3328

Query: 949  KYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYI 1008
            K  KN E+  QLE        N   L   +++LNK +  ++ K +Q    ++ + T Q +
Sbjct: 3329 K--KNYEFSQQLEVNNDLISKN-NQLQQTIDQLNK-DKTVLSKQIQDLANKNNEITNQ-L 3383

Query: 1009 NEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVS---DYESKLAQFTTKLENMEEEMQ 1065
            N  +K+    KQK +E   LNQ ++N      ++ +   D  S+++Q     EN++ +++
Sbjct: 3384 NNKDKIILESKQKSDE---LNQSLSNLMKELHTLKANNDDLNSQISQSKQNEENLQLQIE 3440

Query: 1066 RVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDA 1125
            +  K L D+KQ++ +L   V +   +++ L   KL  E  I K      S  ++ +    
Sbjct: 3441 KQKKLLQDTKQNDNKL---VDDLSKEVETLTSEKLKNE-EIIKQNNAKYSGILKQLQQKN 3496

Query: 1126 NNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTEL 1185
              ++             K Q+ E+ + +   L +   KL+ E ++    ++  +  N ++
Sbjct: 3497 EEINKEKEQFKHDLEGEK-QKNEKLVND---LNQTKDKLSQENEKLKHYLVAFKQNNEQI 3552

Query: 1186 TGHDVVNQEQINQLKSKLEQLNT---ENDNLLSTVAELRSSISSAVD---QRGFEIAELW 1239
            T  +    E I QL  ++  L +   E++ L S  A+++ +  S ++   Q    +    
Sbjct: 3553 TADNKQKDENIQQLMKQINSLKSQLQEDEKLKSQFAKMKENYDSLINKLNQENKSLTHSL 3612

Query: 1240 KQHLAQREADFQKTEHELRVQLSAFESKYEQL----------LDSVQSSTQEETNK---- 1285
             + L   E +  K   +L+       +K  QL          ++++    Q+ +N+    
Sbjct: 3613 NESLKHNE-ELSKNNEKLQQNNELLSNKLNQLGSQDNNKQKEIENMNQKLQKVSNEGKQK 3671

Query: 1286 -IVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXX 1344
                +E++ +L+  L + +    ++ +  ++   Q E+L SE  +E              
Sbjct: 3672 EDQLIEEINNLKFSLIELQRKNEDMNQMLSETKKQNEVL-SEQNNEIQLLKNELENLSKS 3730

Query: 1345 XXXXXXDLRTENQSYKQMQEQSILNINEE-NAQLKKSSXXXXXXXXXXX---XRVNDAEA 1400
                   L+ E +   + +E  I ++ E  N + KK+                +  + E 
Sbjct: 3731 KEDEINSLKEEYERKIKEKEDEIEHLEENCNNEKKKTESYEKKFVEEKGEYESKQQNTET 3790

Query: 1401 KVLELTHQLEL--KDSEIYQKT--------HEYT------ITLTQRNDEFENVRQQLVEY 1444
             + EL  ++EL  K++E   KT        HEY         L + +D F    Q +V+ 
Sbjct: 3791 YIEELETEIELLLKENEQLDKTKYDYDAIQHEYNKVREDLAKLQKEHDNFVEEHQLVVDQ 3850

Query: 1445 EKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQ 1504
             K  E+L       +  L+    E A+  E  + E EI + K   E  +KI E  +   Q
Sbjct: 3851 LKNHEEL-------IGFLKQDKEEIASKLEAQEDEIEIMKTK-ANESEMKIEEYENSQDQ 3902

Query: 1505 VAELNKALEEEVAKTNEM 1522
            +       EEE  ++ ++
Sbjct: 3903 I---RSKYEEEANESKKL 3917



 Score =  116 bits (278), Expect = 7e-24
 Identities = 193/1001 (19%), Positives = 428/1001 (42%), Gaps = 82/1001 (8%)

Query: 619  LESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKEL 678
            + S+K    + L  +Q+ Y+ + +K ++ S +    +     +  L      LS  +   
Sbjct: 1    MSSEKGSESKSLDEIQRIYNRLVEKYSESSSILKSPIKGNQNATQLNSSSLILSQERVNP 60

Query: 679  ALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAK 738
            A V +  +   +    T++ + N       K+   +++ +        + A K+++ L +
Sbjct: 61   ANVSKKYRAFFKDYISTLETI-NQSLTANPKITKSVKQQI--------VKARKLAKHLRE 111

Query: 739  INHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVME-DRRYSLER 797
            +N+EE      Q     + + + ++I+N ++ +  Y+  +            D    L  
Sbjct: 112  LNYEEDISESIQDTSLNEDRVKRVFIDN-QNLMKNYEDDLNHTTPKNPHPNLDDSEVLPD 170

Query: 798  KADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQI 857
              D     ++  +    ++  +E    N L  L  ++ ++ K       +N++L K+N+ 
Sbjct: 171  NMDDSSLIIENVRTRDFKFDPEELNQQNTLDELTQNNEILSK-------DNEKLSKENEQ 223

Query: 858  LLEENQNLQISLSDMQ----QHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHE 913
            L +EN +L   L   +    +  N + +  +       ++ + Q +L +L+   +++T  
Sbjct: 224  LNQENTSLSTLLGSAKSTNLELENTIEQLKSANKELSDKNVEIQAKLINLQKEKEQLTST 283

Query: 914  HQTLIVQK---KKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNN 970
            +  L+ +    KKEI++L          +I  ++ L+ + + N + +  L  +  +  + 
Sbjct: 284  NDKLLTETENLKKEIDELNNANKELNVKSINLQQSLDNEKQNNKKMIQDLNKEKTDLISK 343

Query: 971  IENLNMNVEE----LNKMNLELIDKHVQKQQTQSP-DYTEQYINEINKLNALLKQKDEEI 1025
            IE L M+ +E    LN +N    D   + Q  Q+  +  E+ I ++ K N  L   ++  
Sbjct: 344  IEKLEMDNKEMNSKLNNVNTSYNDLDAKNQNNQTKVNNLEKIIEKLIKENTELANNNKNN 403

Query: 1026 IALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSK--QLLDSKQHNEELQI 1083
             +   ++ N     +S  +D  +K     TK++ + +E   + +  ++L S     +  +
Sbjct: 404  NSKIDELQNQNKDLISASNDMNTKNQSLQTKIDQLNKEKTELEEKNKVLKSNLEGLKSDL 463

Query: 1084 LVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIE---PMSDDANNVDXXXXXXXXXXX 1140
            L + Q+   K     K+  ++   + E  ++SS +E    ++DD N              
Sbjct: 464  LSKNQESTKKNENLQKIIDQL---QNENKLLSSNLENQTKLNDDLNKEKSDLQS------ 514

Query: 1141 XLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTG--------HDVVN 1192
              K++E E+  ++ +   E + K    ++E   KI  L+  N ELT         +D +N
Sbjct: 515  --KIEELEKNNKDLTSNLENNHK---TIEELSNKINDLQNNNKELTSNLEDQNKLNDDLN 569

Query: 1193 QEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQ-HLAQREADFQ 1251
            +E+ + L+SK+E+L+T+N+ L S+    + ++ + VD+    I +L K+  + +      
Sbjct: 570  KEKAD-LQSKIEELSTKNEELESSNKNEKENLQNKVDEFEKIIDQLRKEKEVLEENEKVS 628

Query: 1252 KT----EHELRVQLSAFESKYEQLLDSVQSSTQE-ETNKIVTMEQVTSLQNKLQDKEEHL 1306
            KT    ++++  +L+  +S  +  +D ++ + ++  TN  ++ ++ + L  + ++K + +
Sbjct: 629  KTNIDDDYKVIEELNNEKSDLQSKIDQLEKNNKDLTTNLELSNKEKSDLSLENENKRKEI 688

Query: 1307 RNLQEKYADVINQIEILRSEIED-EKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQ 1365
              L+       N IE L+ +I++ EK                       EN      +E 
Sbjct: 689  DELKSLNNKTNNDIEKLQLQIQELEKSNEQLQKEKEVLSSENNQLKSNVENSE----KEI 744

Query: 1366 SILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTH-QLELKDSEIYQKTHEYT 1424
             ILN  + + Q K                  +   KVL   +  L+ K  E+  K  E  
Sbjct: 745  GILNKEKADLQSKVEELDNNNKELASNLENQNKLNKVLNNENSDLQSKIEELTTKNQELE 804

Query: 1425 ITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIER 1484
             +  + N+E EN++ ++ E EK I++L  +KE+E       +   +NH  T  + +E   
Sbjct: 805  SSNIETNNEKENLQARINELEKIIDEL--QKENE------NLETESNHLRTDLQNNEKTI 856

Query: 1485 VKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEI-VTLNDEITNL 1543
              L ++ N   ++   L K   E    +++  A   ++QT  +N E++  V L ++I + 
Sbjct: 857  ADLNKDKNDLTSKIGELEKNNKEFTTLIDKINASNKDLQT--KNDELQSKVDLLEKILDQ 914

Query: 1544 QNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAV 1584
             N  ++      + +  + D  +  +E L N  NK+L + +
Sbjct: 915  LNKDKSDLITKLEELQTSIDQMKQTNENL-NKENKDLQNKI 954



 Score =  109 bits (263), Expect = 5e-22
 Identities = 173/812 (21%), Positives = 343/812 (42%), Gaps = 94/812 (11%)

Query: 804  SYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQ 863
            +Y ++  ++  + ++ ED  V R  V +D+  +++    ++ H   +    N   L++++
Sbjct: 113  NYEEDISESIQDTSLNEDR-VKR--VFIDNQNLMKNYEDDLNHTTPKNPHPN---LDDSE 166

Query: 864  NLQISLSDMQQHYNALVEKANRTDLA-ESESTKYQTQLRDLESNLKRITHEHQTLIVQKK 922
             L  ++ D     + ++E     D   + E    Q  L +L  N + ++ +++ L     
Sbjct: 167  VLPDNMDDS----SLIIENVRTRDFKFDPEELNQQNTLDELTQNNEILSKDNEKL----S 218

Query: 923  KEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELN 982
            KE E L  E NT + + +   K  N + E  IE +     +L +    I+   +N+++  
Sbjct: 219  KENEQLNQE-NTSLSTLLGSAKSTNLELENTIEQLKSANKELSDKNVEIQAKLINLQKEK 277

Query: 983  KMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSM 1042
            +      DK + +        TE    EI++LN   K+ + + I L Q ++N + +   M
Sbjct: 278  EQLTSTNDKLLTE--------TENLKKEIDELNNANKELNVKSINLQQSLDNEKQNNKKM 329

Query: 1043 VSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTF 1102
            + D   +     +K+E +E          +D+K+ N +L  +    +D +    +   T 
Sbjct: 330  IQDLNKEKTDLISKIEKLE----------MDNKEMNSKLNNVNTSYND-LDAKNQNNQTK 378

Query: 1103 EMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSA 1162
              N+ K    +I    E  +++ NN               K+ E +   Q + ++   S 
Sbjct: 379  VNNLEKIIEKLIKENTELANNNKNNNS-------------KIDELQN--QNKDLISA-SN 422

Query: 1163 KLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRS 1222
             +NT+ Q   TKI QL    TEL   + V +  +  LKS L   N E+        +   
Sbjct: 423  DMNTKNQSLQTKIDQLNKEKTELEEKNKVLKSNLEGLKSDLLSKNQES-------TKKNE 475

Query: 1223 SISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEE 1282
            ++   +DQ   E      + L+    +  K   +L  + S  +SK E+L  + +  T   
Sbjct: 476  NLQKIIDQLQNE-----NKLLSSNLENQTKLNDDLNKEKSDLQSKIEELEKNNKDLTSNL 530

Query: 1283 TNKIVTMEQVTSLQNKLQDKEEHLR-NL--QEKYADVINQIEI-LRSEIEDEKVAFXXXX 1338
             N   T+E++++  N LQ+  + L  NL  Q K  D +N+ +  L+S+IE+         
Sbjct: 531  ENNHKTIEELSNKINDLQNNNKELTSNLEDQNKLNDDLNKEKADLQSKIEE--------- 581

Query: 1339 XXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDA 1398
                        +L + N++ K+  +  +    +   QL+K               ++D 
Sbjct: 582  ------LSTKNEELESSNKNEKENLQNKVDEFEKIIDQLRKEKEVLEENEKVSKTNIDDD 635

Query: 1399 EAKVLELTHQ---LELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDL---T 1452
               + EL ++   L+ K  ++ +   + T  L   N E  ++  +     K I++L    
Sbjct: 636  YKVIEELNNEKSDLQSKIDQLEKNNKDLTTNLELSNKEKSDLSLENENKRKEIDELKSLN 695

Query: 1453 YEKESELAILRLKMHENANHYETMQKESEI---ERVKLIEELNVKITESVSLNKQVAELN 1509
             +  +++  L+L++ E     E +QKE E+   E  +L   +     E   LNK+ A+L 
Sbjct: 696  NKTNNDIEKLQLQIQELEKSNEQLQKEKEVLSSENNQLKSNVENSEKEIGILNKEKADLQ 755

Query: 1510 KALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRD 1569
              +EE      E+ + LENQ      LN+E ++LQ+ +   ++K Q+  S   +T   + 
Sbjct: 756  SKVEELDNNNKELASNLENQNKLNKVLNNENSDLQSKIEELTTKNQELESSNIETNNEK- 814

Query: 1570 EQLDNTMN--KELLDAVPRAELDLAMYMLHQR 1599
            E L   +N  ++++D + +   +L     H R
Sbjct: 815  ENLQARINELEKIIDELQKENENLETESNHLR 846


>UniRef50_A2E8Z5 Cluster: Viral A-type inclusion protein, putative;
            n=1; Trichomonas vaginalis G3|Rep: Viral A-type inclusion
            protein, putative - Trichomonas vaginalis G3
          Length = 4057

 Score =  209 bits (510), Expect = 6e-52
 Identities = 282/1336 (21%), Positives = 599/1336 (44%), Gaps = 142/1336 (10%)

Query: 309  EIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSP 368
            E++EK +    N  E  + I  L+  N Q+   NK L++++ ++ T+ + V    KK   
Sbjct: 2294 EMDEKVTTNETNSNEKERLISNLQKQNKQLENENKTLQSEIKSLQTD-EFVKDQMKKQLN 2352

Query: 369  LISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLN---KDLVDKE 425
               +K      SK++    QL +E      D    K  + K E +IQ LN   +DL + +
Sbjct: 2353 DYEQK-----VSKLEDEKRQLQNEMTKYKDDNSTMKKVLTKQEKIIQKLNTKVEDLTETK 2407

Query: 426  YVI--SEKDTXXXXXXXXXXGKDTL--IAQLQLEHQQHMEG--PSLIHVG----TNTEDV 475
              +  ++ +            K+ L  + +  LE ++ ++G   S+  V     +  E++
Sbjct: 2408 QTMKQTQSEELSSLEEENEQKKEELKHLKEEFLEKEKRLKGLEKSIQKVTEKITSQKEEI 2467

Query: 476  NEIAK---VQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNM---IKV 529
              + K   + +    EL   I + N K+L E L+ ++   + + +++ + ++N+   +K 
Sbjct: 2468 ENLRKQKLIDDNTISELKSSISE-NEKEL-ENLRKSDSDKSDIIEQLKSESENLSMSLKS 2525

Query: 530  KSNHKLKLKQMQKTIDNFS-KVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQ-LHLVD 587
            +SN++ +L ++Q  I   + ++SD   ++      L  L +KV E EE+    Q L+   
Sbjct: 2526 RSNYENELTKLQNKIQKLNDQISDKEDDLKSKEILLEKLQKKVQETEEKFSETQKLNKTM 2585

Query: 588  YDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKY----DEVEDK 643
             D    I + +  + ++ME  ++T  K I  L     +L +++ IL+ K     D+ ++K
Sbjct: 2586 KDENANISNQL--RALQMELNSKT--KQIEKLVKDNTNLKEKVTILEFKQSNFDDDNKEK 2641

Query: 644  LADISQLQSDQ-------VCSEIKSVHLEE---QIDALSASKKELALVIEN----LKLDK 689
               I  L++D        + +E     ++E   QI  L+   KE    ++N    LK   
Sbjct: 2642 EEKIENLENDNFNLKKQIILNEEYKKQIDELKFQISQLNYDNKEKVTRLQNENTLLKTKS 2701

Query: 690  EQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQT 749
             Q    +  ++ ++ED+ ++++  ++   DL  K  +   ++  E+  +    +  KI  
Sbjct: 2702 LQNKSELNTVKKEREDLQSEIEE-LKMKFDLEQKENENLKKQNKEIKNQFETTKSEKIYL 2760

Query: 750  QFGI-DAKIQERDLYIEN--IESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYL 806
            +  I +AK +  DL  +N  +ESEL K +  I RL  S   + D +  L +   ++    
Sbjct: 2761 EKDISNAKTELNDLLDKNNKLESELRKKEREITRLSYSENKLNDLQIELNKLKSEMKDKT 2820

Query: 807  QEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQ---LLEIEHENKELQKKNQILLE-EN 862
             E ++  +E +++ +E+ +        ++ ++ +   +  +E+E K++QK+N+ + + EN
Sbjct: 2821 SEIERLSNELSLKSEEIYSFSCSSNSFEKEIQTKSDKIKSLENEIKKVQKENEQIKDLEN 2880

Query: 863  Q---------NLQISLSDMQQHYNALVEKAN------RTDLA-----ESESTKYQTQLRD 902
            Q         NLQ       + +  ++   N      + DL+     + E+ K   Q  +
Sbjct: 2881 QLNEKSLIIENLQKEFKQKDEKHETVLNSMNDKMKGLQNDLSVLSDLQRENEKITKQNEE 2940

Query: 903  LESNLKRITHEHQTLIVQKKKEIEDLE---IEFNTQIESAIRDKKVLNEKYEKNIEYV-T 958
            ++S  K++  E+     + KK    L+   IE NT ++  ++ K+     YE  +E   T
Sbjct: 2941 IKSQNKKLKEENDDKNREIKKLSNTLQKGDIEMNT-LKDLLQTKEEKIRNYEDILEKTKT 2999

Query: 959  QLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKL---N 1015
            Q+E +  E+   +++ N  + +L K  LE  D  +     +S  + ++  ++I  L   N
Sbjct: 3000 QMEDKNYEFSKTVKDQNDKINQLEK-ELEQRDLELDDLTNKSKSFDDEKNDKIQSLTTEN 3058

Query: 1016 ALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKL----ENMEEEMQRVSKQL 1071
              LK+++  +  +   +  +       + + ES+L   ++ L    E  E E+ ++ K++
Sbjct: 3059 KNLKKENRTLKGIINSVKKSSNELEERIRNLESQLKSHSSSLIELQEKKETEISKLQKEI 3118

Query: 1072 LDS----KQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANN 1127
             +     K  NE+L    +E +   +E++E K      + + E   I    E + +   +
Sbjct: 3119 DEREEKIKSQNEKLSNCRKEVEKTKQEIEEMKAKLNSQLTE-EIQTIKGEKEDLLEKIKS 3177

Query: 1128 VDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTG 1187
            ++            LK + ++   + +SV++E+  KL  E+ +      Q+++L  E+  
Sbjct: 3178 INKERDELSQQIKSLKRENDDLQQKLKSVIEERE-KLEKEVNDLTQ---QIKSLKNEIEE 3233

Query: 1188 HDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAE--LWKQHLAQ 1245
                ++++I     KL+  N E   L +   +L+  + S  ++R     E  L  + L  
Sbjct: 3234 QKEKSKKEIENFSEKLKSSNEEKQKLQNQNDDLQQKLESIKEERENLKRENDLINKKLKS 3293

Query: 1246 READFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEH 1305
            +  + QK   E+    S  +S  E  ++   +ST E+ NK +  +Q+  L  K+ D    
Sbjct: 3294 QSEELQKLNKEIDYSKSQIDSLDE--VNKKLNSTNEQENKQLN-DQINKLTTKVNDLNNE 3350

Query: 1306 LRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQ 1365
            ++ L  +  D+I+Q + L  ++  +   F                + +  N+  K+ +E+
Sbjct: 3351 IKKLTSEKNDLIDQNKRLNEDLSKKVNQFDE--------------ETQKLNEQLKRSKEE 3396

Query: 1366 SILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTI 1425
             I +IN +N +L   +            ++N    K+  LT++   +  + +    E  +
Sbjct: 3397 -INDINNQNKKLDSLNNDLKQENN----KLNHEITKLNSLTNEFN-EQKKKFDSVKEENL 3450

Query: 1426 TLTQRNDEF----ENVRQQLVEYEKRIEDLTYEK-ESELAILRLKMHENANHYETMQKES 1480
             L   N+E     E + ++L    ++I+++T E  + ++ +L  K++EN    ET  ++ 
Sbjct: 3451 RLNSLNNELKQENEEISKKLKSLNEQIKEITNENNQDQIDLLNKKLNEN----ETFTRKL 3506

Query: 1481 EIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEI 1540
              ++  L ++L +   E+  LNK+V +L++ LEE  +K  E     EN  I++   N+ +
Sbjct: 3507 NDDKENLAKKLQISNEENKKLNKKVEDLSEELEE--SKQRE-----ENSLIDLQNKNETL 3559

Query: 1541 TNLQNMVRASSSKIQK 1556
             NL+  ++    +IQ+
Sbjct: 3560 ENLKTQIKKQKQQIQE 3575



 Score =  207 bits (505), Expect = 2e-51
 Identities = 280/1420 (19%), Positives = 623/1420 (43%), Gaps = 99/1420 (6%)

Query: 216  QQMTKMQENFIAMEAEWKDEKQRLLK-----DIESKDVRISSLEEANKL---LEAARFEI 267
            Q++    EN   + +  K E   L K     D+++K      L + N L   L+      
Sbjct: 2007 QKIINESENLQFLVSTLKTENNTLKKVTQDNDLQNKKTNEDLLSQINDLQNKLKETEKSS 2066

Query: 268  SLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKK 327
             ++ SK   +L +              L    ++    E   ++EK         +L KK
Sbjct: 2067 QIQKSKYESQLNEIQSKLNQSIKDNSDL----MDKHENELKNLDEKLQESQKQKNDLEKK 2122

Query: 328  IELLEHLNCQIRQTNKELENKL-ATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPW 386
             E+   L   + + NK  + K   T+   +   S   K    +   +  +N  + + +  
Sbjct: 2123 FEMNSKL---LNENNKLRQEKFDKTLEELTNVKSENGKLKEQIDDLEKEKNEMTILLNTT 2179

Query: 387  SQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKD 446
                +E L Q+  KK+N   I +L+M     N      E +  + D             D
Sbjct: 2180 QNNQNEDL-QNLQKKLNAT-IDELKMTTNDYNSLKEKFEKLNGKSDNDNSLISSLKREND 2237

Query: 447  TLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELND-EIKDVNVKDLIEKL 505
             +   LQ   +++     ++ +  N + ++++ K  +++ ++L   E ++  +K  + ++
Sbjct: 2238 KMKNDLQKTQEENKS--LVLKLNENEKTISKLQKTNDEISRKLTFVETENGELKLTVNEM 2295

Query: 506  KSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIV-RLTEEL 564
               +E++T  N+      + +I        +L+   KT+ +  K   +++ +  ++ ++L
Sbjct: 2296 ---DEKVTT-NETNSNEKERLISNLQKQNKQLENENKTLQSEIKSLQTDEFVKDQMKKQL 2351

Query: 565  HHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAIS-LLESQK 623
            +   QKV++LE+EK  LQ  +  Y         V  K  ++     T+++ ++   ++ K
Sbjct: 2352 NDYEQKVSKLEDEKRQLQNEMTKYKDDNSTMKKVLTKQEKIIQKLNTKVEDLTETKQTMK 2411

Query: 624  FDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIE 683
                +EL  L++   E E K  ++  L+ + +  E +   LE+ I  ++         IE
Sbjct: 2412 QTQSEELSSLEE---ENEQKKEELKHLKEEFLEKEKRLKGLEKSIQKVTEKITSQKEEIE 2468

Query: 684  NLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKIS---ELLAKIN 740
            NL+  K     TI +L++   +   +L+N  + + D +D +E++ +E  +    L ++ N
Sbjct: 2469 NLRKQKLIDDNTISELKSSISENEKELENLRKSDSDKSDIIEQLKSESENLSMSLKSRSN 2528

Query: 741  HE-EQSKIQTQFG-IDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERK 798
            +E E +K+Q +   ++ +I +++  +++ E  L K + ++   EE  +  +    +++ +
Sbjct: 2529 YENELTKLQNKIQKLNDQISDKEDDLKSKEILLEKLQKKVQETEEKFSETQKLNKTMKDE 2588

Query: 799  ADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQIL 858
               + + L+  Q   +  T Q ++LV     L +   ++E +    + +NKE ++K + L
Sbjct: 2589 NANISNQLRALQMELNSKTKQIEKLVKDNTNLKEKVTILEFKQSNFDDDNKEKEEKIENL 2648

Query: 859  LEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLI 918
              +N NL+  +   +++   + E   +      ++ +  T+L++  + LK  + ++++ +
Sbjct: 2649 ENDNFNLKKQIILNEEYKKQIDELKFQISQLNYDNKEKVTRLQNENTLLKTKSLQNKSEL 2708

Query: 919  VQKKKEIEDLEIEF-NTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQE---YKNNIENL 974
               KKE EDL+ E    +++  +  K+  N K ++N E   Q E    E    + +I N 
Sbjct: 2709 NTVKKEREDLQSEIEELKMKFDLEQKENENLK-KQNKEIKNQFETTKSEKIYLEKDISNA 2767

Query: 975  NMNVEELNKMNLELIDKHVQKQQTQSP--DYTEQYIN----EINKLNALLKQKDEEIIAL 1028
               + +L   N +L +  ++K++ +     Y+E  +N    E+NKL + +K K  EI  L
Sbjct: 2768 KTELNDLLDKNNKL-ESELRKKEREITRLSYSENKLNDLQIELNKLKSEMKDKTSEIERL 2826

Query: 1029 NQKIN--NAQV-SYMSMVSDYESKLAQFTTKLENMEEEMQRVSK---QLLDSKQHNEELQ 1082
            + +++  + ++ S+    + +E ++   + K++++E E+++V K   Q+ D +    E  
Sbjct: 2827 SNELSLKSEEIYSFSCSSNSFEKEIQTKSDKIKSLENEIKKVQKENEQIKDLENQLNEKS 2886

Query: 1083 ILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSD-DANNVDXXXXXXXXXXXX 1141
            +++     + K+ K+ K    +N    +   + + +  +SD    N              
Sbjct: 2887 LIIENLQKEFKQ-KDEKHETVLNSMNDKMKGLQNDLSVLSDLQRENEKITKQNEEIKSQN 2945

Query: 1142 LKVQEE-----EEFIQERSVLQEQSAKLNT---------ELQECYTKII-----QLETLN 1182
             K++EE      E  +  + LQ+   ++NT         E    Y  I+     Q+E  N
Sbjct: 2946 KKLKEENDDKNREIKKLSNTLQKGDIEMNTLKDLLQTKEEKIRNYEDILEKTKTQMEDKN 3005

Query: 1183 TELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQH 1242
             E +       ++INQL+ +LEQ + E D+L +         +  +     E   L K++
Sbjct: 3006 YEFSKTVKDQNDKINQLEKELEQRDLELDDLTNKSKSFDDEKNDKIQSLTTENKNLKKEN 3065

Query: 1243 LAQREA--DFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQ 1300
               +      +K+ +EL  ++   ES+    L S  SS  E   K  T  +++ LQ ++ 
Sbjct: 3066 RTLKGIINSVKKSSNELEERIRNLESQ----LKSHSSSLIELQEKKET--EISKLQKEID 3119

Query: 1301 DKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYK 1360
            ++EE +++  EK ++   ++E  + EIE+ K                   DL  + +S  
Sbjct: 3120 EREEKIKSQNEKLSNCRKEVEKTKQEIEEMKAKLNSQLTEEIQTIKGEKEDLLEKIKSIN 3179

Query: 1361 QMQE---QSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIY 1417
            + ++   Q I ++  EN  L++               VND   ++  L +++E +  +  
Sbjct: 3180 KERDELSQQIKSLKRENDDLQQKLKSVIEEREKLEKEVNDLTQQIKSLKNEIEEQKEKSK 3239

Query: 1418 QKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKES---ELAILRLKMHENANHYE 1474
            ++   ++  L   N+E + ++ Q  + ++++E +  E+E+   E  ++  K+   +   +
Sbjct: 3240 KEIENFSEKLKSSNEEKQKLQNQNDDLQQKLESIKEERENLKRENDLINKKLKSQSEELQ 3299

Query: 1475 TMQKESEIERVKL--IEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIE 1532
             + KE +  + ++  ++E+N K+    S N+Q    NK L +++   N++ T + +   E
Sbjct: 3300 KLNKEIDYSKSQIDSLDEVNKKLN---STNEQE---NKQLNDQI---NKLTTKVNDLNNE 3350

Query: 1533 IVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQL 1572
            I  L  E  +L +  +  +  + K V+   +  Q  +EQL
Sbjct: 3351 IKKLTSEKNDLIDQNKRLNEDLSKKVNQFDEETQKLNEQL 3390



 Score =  200 bits (489), Expect = 2e-49
 Identities = 296/1501 (19%), Positives = 645/1501 (42%), Gaps = 117/1501 (7%)

Query: 148  SNTIKEKDNA-LSVLQVKMKIMETTILDLQEKINEKDQI---IEAKNKATTXXXXXXXXX 203
            +N+I ++ NA + +L+ ++     TI DLQ+ INE + +   +                 
Sbjct: 1978 NNSIVKQQNAKIEMLKQQLIDQNKTIEDLQKIINESENLQFLVSTLKTENNTLKKVTQDN 2037

Query: 204  XXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRIS-SLEEANKLLEA 262
                    ED   Q+  +Q      E   + +K +    +     +++ S+++ + L++ 
Sbjct: 2038 DLQNKKTNEDLLSQINDLQNKLKETEKSSQIQKSKYESQLNEIQSKLNQSIKDNSDLMDK 2097

Query: 263  ARFEIS------LEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIE-EKGS 315
               E+        E  K   +LE+              L ++  + + EE T ++ E G 
Sbjct: 2098 HENELKNLDEKLQESQKQKNDLEKKFEMNSKLLNENNKLRQEKFDKTLEELTNVKSENGK 2157

Query: 316  LEIANMTELTK-KIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKS 374
            L+   + +L K K E+   LN      N++L+N    +      +   +   + L  +  
Sbjct: 2158 LK-EQIDDLEKEKNEMTILLNTTQNNQNEDLQNLQKKLNATIDELKMTTNDYNSLKEKFE 2216

Query: 375  GRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTX 434
              N   K  +  S +SS  L ++ DK   KN++ K +   +SL   L + E  IS+    
Sbjct: 2217 KLN--GKSDNDNSLISS--LKRENDKM--KNDLQKTQEENKSLVLKLNENEKTISKLQKT 2270

Query: 435  XXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTED--VNEIAKVQEQLKQE---L 489
                       +T   +L+L   +  E  +     +N ++  ++ + K  +QL+ E   L
Sbjct: 2271 NDEISRKLTFVETENGELKLTVNEMDEKVTTNETNSNEKERLISNLQKQNKQLENENKTL 2330

Query: 490  NDEIKDVN----VKDLIEK-LKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTI 544
              EIK +     VKD ++K L   E+++++L DE       M K K ++    K + K  
Sbjct: 2331 QSEIKSLQTDEFVKDQMKKQLNDYEQKVSKLEDEKRQLQNEMTKYKDDNSTMKKVLTKQE 2390

Query: 545  DNFSKVSDSNKEIVRLTEELHHL-SQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMI 603
                K++   +++    + +    S++++ LEEE    +  L      + ++ +  +K  
Sbjct: 2391 KIIQKLNTKVEDLTETKQTMKQTQSEELSSLEEENEQKKEEL------KHLKEEFLEKEK 2444

Query: 604  EMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSV- 662
             ++ L ++  K    + SQK    +E+  L+++      KL D      D   SE+KS  
Sbjct: 2445 RLKGLEKSIQKVTEKITSQK----EEIENLRKQ------KLID------DNTISELKSSI 2488

Query: 663  -HLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQE-NMDL 720
               E++++ L  S  + + +IE LK + E L  ++K   N  E+ + KLQN IQ+ N  +
Sbjct: 2489 SENEKELENLRKSDSDKSDIIEQLKSESENLSMSLKSRSN-YENELTKLQNKIQKLNDQI 2547

Query: 721  TDKLEKMSAEKI--SELLAKINHEEQSKIQTQFGIDAKIQERDLYIEN----IESELSKY 774
            +DK + + +++I   +L  K+   E+   +TQ  ++  +++ +  I N    ++ EL+  
Sbjct: 2548 SDKEDDLKSKEILLEKLQKKVQETEEKFSETQ-KLNKTMKDENANISNQLRALQMELNSK 2606

Query: 775  KSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHD 834
              +I +L +    ++++   LE K        +EK++           L  ++ +  ++ 
Sbjct: 2607 TKQIEKLVKDNTNLKEKVTILEFKQSNFDDDNKEKEEKIENLENDNFNLKKQIILNEEYK 2666

Query: 835  RVVEK---QLLEIEHENKE----LQKKNQIL----LEENQNLQISLSDMQQHYNALVEKA 883
            + +++   Q+ ++ ++NKE    LQ +N +L    L+    L     + +   + + E  
Sbjct: 2667 KQIDELKFQISQLNYDNKEKVTRLQNENTLLKTKSLQNKSELNTVKKEREDLQSEIEELK 2726

Query: 884  NRTDLAESESTKYQTQLRDLESNLKRITHEHQTL---IVQKKKEIEDLEIEFNTQIESAI 940
             + DL + E+   + Q +++++  +    E   L   I   K E+ DL ++ N ++ES +
Sbjct: 2727 MKFDLEQKENENLKKQNKEIKNQFETTKSEKIYLEKDISNAKTELNDL-LDKNNKLESEL 2785

Query: 941  RDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQS 1000
            R K+    +   +   +  L+ +L + K+ +++    +E L+   L L  + +      S
Sbjct: 2786 RKKEREITRLSYSENKLNDLQIELNKLKSEMKDKTSEIERLSN-ELSLKSEEIYSFSCSS 2844

Query: 1001 PDYTEQYINEINKLNAL------LKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFT 1054
              + ++   + +K+ +L      +++++E+I  L  ++N   +   ++  +++ K  +  
Sbjct: 2845 NSFEKEIQTKSDKIKSLENEIKKVQKENEQIKDLENQLNEKSLIIENLQKEFKQKDEKHE 2904

Query: 1055 TKLENMEEEMQRVSKQLL---DSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEG 1111
            T L +M ++M+ +   L    D ++ NE++     E   Q K+LKE        I K   
Sbjct: 2905 TVLNSMNDKMKGLQNDLSVLSDLQRENEKITKQNEEIKSQNKKLKEENDDKNREIKKLSN 2964

Query: 1112 MIISSTIE--PMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQ 1169
             +    IE   + D     +             K Q E++  +    +++Q+ K+N   +
Sbjct: 2965 TLQKGDIEMNTLKDLLQTKEEKIRNYEDILEKTKTQMEDKNYEFSKTVKDQNDKINQLEK 3024

Query: 1170 ECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVD 1229
            E   + ++L+ L  +    D    ++I  L ++ + L  EN  L   +  ++ S S+ ++
Sbjct: 3025 ELEQRDLELDDLTNKSKSFDDEKNDKIQSLTTENKNLKKENRTLKGIINSVKKS-SNELE 3083

Query: 1230 QRGFEIAELWKQHLA-------QREADFQKTEHELRVQLSAFESKYEQLLD---SVQSST 1279
            +R   +    K H +       ++E +  K + E+  +    +S+ E+L +    V+ + 
Sbjct: 3084 ERIRNLESQLKSHSSSLIELQEKKETEISKLQKEIDEREEKIKSQNEKLSNCRKEVEKTK 3143

Query: 1280 QE------ETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVA 1333
            QE      + N  +T E++ +++ + +D  E ++++ ++  ++  QI+ L+ E +D +  
Sbjct: 3144 QEIEEMKAKLNSQLT-EEIQTIKGEKEDLLEKIKSINKERDELSQQIKSLKRENDDLQQK 3202

Query: 1334 FXXXXXXXXXXXXXXXXDLRTENQSYK-QMQEQSILNINE-ENAQLK-KSSXXXXXXXXX 1390
                             DL  + +S K +++EQ   +  E EN   K KSS         
Sbjct: 3203 LKSVIEEREKLEKEVN-DLTQQIKSLKNEIEEQKEKSKKEIENFSEKLKSSNEEKQKLQN 3261

Query: 1391 XXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIED 1450
                +      + E    L+ ++  I +K    +  L + N E +  + Q+   ++  + 
Sbjct: 3262 QNDDLQQKLESIKEERENLKRENDLINKKLKSQSEELQKLNKEIDYSKSQIDSLDEVNKK 3321

Query: 1451 LTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNK 1510
            L    E E      ++++  N   T   +   E  KL  E N  I ++  LN+ +++   
Sbjct: 3322 LNSTNEQE----NKQLNDQINKLTTKVNDLNNEIKKLTSEKNDLIDQNKRLNEDLSKKVN 3377

Query: 1511 ALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDE 1570
              +EE  K NE     + +  +I   N ++ +L N ++  ++K+   ++  +      +E
Sbjct: 3378 QFDEETQKLNEQLKRSKEEINDINNQNKKLDSLNNDLKQENNKLNHEITKLNSLTNEFNE 3437

Query: 1571 Q 1571
            Q
Sbjct: 3438 Q 3438



 Score =  198 bits (484), Expect = 8e-49
 Identities = 316/1501 (21%), Positives = 664/1501 (44%), Gaps = 134/1501 (8%)

Query: 140  QLGDVTHLSNTIKEK--DNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXX 197
            ++ D+T     +K K  DN L V++ +++  +    DL+EKI EKD  I+   +      
Sbjct: 719  KMKDLTDEMENLKRKLLDNELDVVKDQLQKEKQKSQDLEEKIEEKDSTIQILKEKIN--- 775

Query: 198  XXXXXXXXXXXXXXEDTKQQMTKM---QENFIAMEAEWKDEKQRLLKDI-ESKDVRISSL 253
                          E++K+   K+   ++  IA+  +  +E Q L+K+  ES   +ISSL
Sbjct: 776  -----------ENLEESKKSYDKLMNDKQEEIALLQKQINELQELIKNNGESSKTKISSL 824

Query: 254  EEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAK--QSIEPSC-EEKTEI 310
             + N  L     +++    +   ++                L K  Q+++    + K++I
Sbjct: 825  LQENTNLNTKIQQLNSLLKQKDDKINDLQNEINDLTQNKIDLEKQIQNLQTIIFDSKSQI 884

Query: 311  EEKGSLEIANMTELTKKI-ELLEHLNCQIRQTNKELE------NKLAT-MGTESKAVSSP 362
            E     +I+ + +L K   E ++ LN +I+QT  EL+       KL   +  E K     
Sbjct: 885  ESLNE-KISGLQQLLKSSQETIDSLNDKIKQTQIELQESKDFAEKLQNDINEEKKKTEDY 943

Query: 363  SKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLV 422
              K   +      RN   + +   +  ++E + Q  DK   K+EI +L   I  LN  + 
Sbjct: 944  QLKLDDIDRLTKERNLLKETEKSLTLTNAENM-QTIDKL--KDEIEQLNDKISQLNTTID 1000

Query: 423  DKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQ 482
                VIS+KD             + +      ++Q+ +E      +    E++ +I+K  
Sbjct: 1001 QLNDVISKKDEEIKQDLQKFELSEKVHQAAINDYQKQLEHHE-EQITLLEEEIEKISKEN 1059

Query: 483  EQLKQE-LNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKV---KSNHKLKLK 538
              LK + L +E K  +  D+ ++    + +I QL +E+     N+ K+     N +++++
Sbjct: 1060 SDLKAKILENEAKLDDFDDVSKQNSEYKAKIEQLEEELADYESNLQKLSEENGNLEIQIE 1119

Query: 539  QMQ-KTIDN--FSKVSDSNKEIVRLTEELHHL-------SQKVAELEEEKGNLQLHLVDY 588
            +++ KT+ N  F+++   N ++     EL  L        Q +A+ ++E  +L   ++D 
Sbjct: 1120 EIKLKTVPNTDFNELRTKNTDLEAQIRELKRLLANDDGNKQVIAQKDKEILSLNQTIIDL 1179

Query: 589  DSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADIS 648
                 + +D  K  IEM    +T     S    +    +++ ++    +D +++KL +++
Sbjct: 1180 QHNNQLLNDKIKD-IEM---TKTNYPERSFNNDELHQTIEDNNV--SMFD-MQNKL-NLA 1231

Query: 649  QLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMN 708
             L+  Q   EI+  +L+ ++ +L +  +E+   I  LK         I +L ND   + N
Sbjct: 1232 NLKLKQSEKEIQ--NLKNELLSLQSENEEMNSTINMLKQSLTSKENEINEL-NDSVTVKN 1288

Query: 709  -KLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENI 767
             +++  +++N    DK      +++  L + + H     IQ +      I  ++  I+N+
Sbjct: 1289 SQIEEILKKNQVKFDKTGN-KEQQLQVLNSSLKHSNDI-IQEK---GKTIDSQNKLIKNL 1343

Query: 768  ESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRL 827
            E    K + +   L+ +++ + +    LE+   +L S LQ  +    +   QE EL+  L
Sbjct: 1344 EDTKQKLQKQNFDLQNNVSNLTN---DLEKTKRELLS-LQNSKNDNIKQLEQEKELI--L 1397

Query: 828  AVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTD 887
                + +++ E+++  +  +   LQ  N I  ++N+ +Q +L ++Q+  N L    N T 
Sbjct: 1398 KQKENENKISEEKIKNLTLQISNLQ--NTISQKDNE-IQNNLQNLQKVSNELDFIKNSTK 1454

Query: 888  LAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFN---TQIESAI---- 940
              E++ T+ +    D+ +NL+++  +      +K KE +D   E +   +Q+E+      
Sbjct: 1455 DHENDLTEKE----DVINNLRKLFDDKMKENEKKTKEFQDSLREKDLMISQLENKTMFFD 1510

Query: 941  RDKKVLNEKYEK-NIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQ 999
            +  K  ++K +   I+ VT  + +L+E +N + N    ++EL K N E   K +Q +   
Sbjct: 1511 QQMKSKDDKIDSLQIQNVT-FQGELKEIQNKLINSLKQIDELQKEN-ESFQKELQTRDQN 1568

Query: 1000 SPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLEN 1059
              D  +Q    I +L A + Q +EEI + ++ +NN Q    + +++YE++      K++ 
Sbjct: 1569 LDDSHKQ----IEELQAKIDQYEEEIKSKDENLNNLQ----NKINNYENESKTNNEKIKE 1620

Query: 1060 MEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELK-ETK-LTFEMNIPKTEGMIISST 1117
            ME + +    Q+ D + +  + +   ++   ++++L+ E K  + ++N  + E    S  
Sbjct: 1621 MEGKQKSNELQINDLQNNVSQTENENKQLKSELEKLQTEIKSKSDQLNEIQNESKSQSEQ 1680

Query: 1118 IEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQ 1177
            I     +   +             L+ +E E F +E     +     + +++E   KI Q
Sbjct: 1681 IVTFQGELKELQNKLTSSLKQIDELQ-KENESFQKELQTRDQNLDDSHKQIEELQAKIDQ 1739

Query: 1178 LETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAE 1237
             E    E+   D    E +N L++K+     E+      + E+     S       +I +
Sbjct: 1740 YE---EEIKSKD----ENLNNLQNKINNYENESKTNNEKIKEMEGKQKS----NELQIND 1788

Query: 1238 LWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVT-MEQVTSLQ 1296
            L + +++Q E + ++ + EL    +  +SK +Q L+ +Q+ ++ ++ +IVT  ++V S  
Sbjct: 1789 L-QNNVSQTENENKQLKSELEKLQTEIKSKSDQ-LNEIQNESKSQSEQIVTFQDEVKSKD 1846

Query: 1297 NKLQDKEEHLRNLQEKYADVINQIE---ILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLR 1353
             KLQ +EE ++ L+ K  ++ N +     L+ ++ D +                      
Sbjct: 1847 EKLQTQEEQIKELENKLNELENSLRNKGDLQVQLNDREKELNNLKKVNENLVKQVEDLQV 1906

Query: 1354 TENQSYKQMQE--QSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLEL 1411
             + QS K++ E  + + N+   NA LKK +             +   + ++ ELT+    
Sbjct: 1907 NKEQSDKKLSENDEELTNLRRNNADLKKQNEKLRENKEKNESEIISLQNRLSELTNSHND 1966

Query: 1412 KDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDL-TYEKESE-LAILRLKMHEN 1469
            +   + +K  E    + Q+N + E ++QQL++  K IEDL     ESE L  L   +   
Sbjct: 1967 ELFTVKRKLEENNSIVKQQNAKIEMLKQQLIDQNKTIEDLQKIINESENLQFLVSTLKTE 2026

Query: 1470 ANHYETMQKESEIERVKLIEEL---------NVKITE---SVSLNKQVAELNKALEEEVA 1517
             N  + + ++++++  K  E+L          +K TE    +  +K  ++LN+   +   
Sbjct: 2027 NNTLKKVTQDNDLQNKKTNEDLLSQINDLQNKLKETEKSSQIQKSKYESQLNEIQSKLNQ 2086

Query: 1518 KTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMN 1577
               +    ++  E E+  L++++   Q        K + +    ++  + R E+ D T+ 
Sbjct: 2087 SIKDNSDLMDKHENELKNLDEKLQESQKQKNDLEKKFEMNSKLLNENNKLRQEKFDKTLE 2146

Query: 1578 K 1578
            +
Sbjct: 2147 E 2147



 Score =  180 bits (438), Expect = 3e-43
 Identities = 282/1537 (18%), Positives = 638/1537 (41%), Gaps = 93/1537 (6%)

Query: 94   LANTLKQKEILMEKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKE 153
            L N + Q E   +++K   EL K    T ++               Q   +      +KE
Sbjct: 1635 LQNNVSQTENENKQLKS--ELEKLQ--TEIKSKSDQLNEIQNESKSQSEQIVTFQGELKE 1690

Query: 154  KDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXED 213
              N L+    ++  ++      Q+++  +DQ ++  +K                    E+
Sbjct: 1691 LQNKLTSSLKQIDELQKENESFQKELQTRDQNLDDSHKQIEELQAKIDQYEEEIKSKDEN 1750

Query: 214  TKQQMTKMQENFIAMEAEWKDEKQRLLKDIE-SKDVRISSLEEANKLLEAARFEISLEHS 272
                  K+  N    E++  +EK + ++  + S +++I+ L+      E    ++  E  
Sbjct: 1751 LNNLQNKI--NNYENESKTNNEKIKEMEGKQKSNELQINDLQNNVSQTENENKQLKSELE 1808

Query: 273  KLAQELEQXXXXXXXXXXXXXXLAKQSIE-----PSCEEKTEIEEKGSLEIAN-MTELTK 326
            KL  E++                ++Q +       S +EK + +E+   E+ N + EL  
Sbjct: 1809 KLQTEIKSKSDQLNEIQNESKSQSEQIVTFQDEVKSKDEKLQTQEEQIKELENKLNELEN 1868

Query: 327  KIELLEHLNCQIRQTNKELENKLATMGTESKAVSS---PSKKGSPLISRKSGRNTASKMK 383
             +     L  Q+    KEL N         K V       ++    +S      T  +  
Sbjct: 1869 SLRNKGDLQVQLNDREKELNNLKKVNENLVKQVEDLQVNKEQSDKKLSENDEELTNLRRN 1928

Query: 384  SPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXX 443
            +   +  +E L ++ +K  N++EI  L+  +  L     D+ + +  K            
Sbjct: 1929 NADLKKQNEKLRENKEK--NESEIISLQNRLSELTNSHNDELFTVKRKLEENNSIVKQQN 1986

Query: 444  GKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIE 503
             K  ++ Q  ++  + +E   L  +   +E++  +      LK E N+ +K V   + ++
Sbjct: 1987 AKIEMLKQQLIDQNKTIE--DLQKIINESENLQFLVST---LKTE-NNTLKKVTQDNDLQ 2040

Query: 504  KLKSAEEQITQLND---EIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRL 560
              K+ E+ ++Q+ND   ++    K+    KS ++ +L ++Q  ++    + D++  + + 
Sbjct: 2041 NKKTNEDLLSQINDLQNKLKETEKSSQIQKSKYESQLNEIQSKLNQ--SIKDNSDLMDKH 2098

Query: 561  TEELHHLSQKVAELEEEKGNLQLHL-----VDYDSGRMIESDVYKKMIEMENLAET--RL 613
              EL +L +K+ E +++K +L+        +  ++ ++ +    K + E+ N+     +L
Sbjct: 2099 ENELKNLDEKLQESQKQKNDLEKKFEMNSKLLNENNKLRQEKFDKTLEELTNVKSENGKL 2158

Query: 614  KA-ISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVH-LEEQIDAL 671
            K  I  LE +K ++   L+  Q   +E    L        D++       + L+E+ + L
Sbjct: 2159 KEQIDDLEKEKNEMTILLNTTQNNQNEDLQNLQKKLNATIDELKMTTNDYNSLKEKFEKL 2218

Query: 672  SASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEK 731
            +        +I +LK + +++   ++  + + + ++ KL     EN     KL+K + E 
Sbjct: 2219 NGKSDNDNSLISSLKRENDKMKNDLQKTQEENKSLVLKLN----ENEKTISKLQKTNDE- 2273

Query: 732  ISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDR 791
            IS  L  +  E      T   +D K+   +      E  +S  + +  +LE     ++  
Sbjct: 2274 ISRKLTFVETENGELKLTVNEMDEKVTTNETNSNEKERLISNLQKQNKQLENENKTLQSE 2333

Query: 792  RYSLERKA---DQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHEN 848
              SL+      DQ+   L + ++  S+   ++ +L N +    D +  ++K L + E   
Sbjct: 2334 IKSLQTDEFVKDQMKKQLNDYEQKVSKLEDEKRQLQNEMTKYKDDNSTMKKVLTKQEKII 2393

Query: 849  KELQKKNQILLEENQNL-QISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNL 907
            ++L  K + L E  Q + Q    ++        +K       + E  + + +L+ LE ++
Sbjct: 2394 QKLNTKVEDLTETKQTMKQTQSEELSSLEEENEQKKEELKHLKEEFLEKEKRLKGLEKSI 2453

Query: 908  KRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQ---- 963
            +++T +    I  +K+EIE+L  +     ++ I + K    + EK +E + + ++     
Sbjct: 2454 QKVTEK----ITSQKEEIENLRKQKLID-DNTISELKSSISENEKELENLRKSDSDKSDI 2508

Query: 964  LQEYKNNIENLNMNVEELNKMNLEL--IDKHVQKQQTQSPDYTEQYINEINKLNALLK-- 1019
            +++ K+  ENL+M+++  +    EL  +   +QK   Q  D  +   ++   L  L K  
Sbjct: 2509 IEQLKSESENLSMSLKSRSNYENELTKLQNKIQKLNDQISDKEDDLKSKEILLEKLQKKV 2568

Query: 1020 QKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNE 1079
            Q+ EE  +  QK+N       + +S+   +L     +L +  ++++++ K   + K+   
Sbjct: 2569 QETEEKFSETQKLNKTMKDENANISN---QLRALQMELNSKTKQIEKLVKDNTNLKEKVT 2625

Query: 1080 ELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXX 1139
             L+      DD  KE +E     E +    +  II +       D               
Sbjct: 2626 ILEFKQSNFDDDNKEKEEKIENLENDNFNLKKQIILNEEYKKQIDELKFQISQLNYDNKE 2685

Query: 1140 XXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQ---EQI 1196
               ++Q E   ++ +S LQ +S +LNT  +E      ++E L  +       N+   +Q 
Sbjct: 2686 KVTRLQNENTLLKTKS-LQNKS-ELNTVKKEREDLQSEIEELKMKFDLEQKENENLKKQN 2743

Query: 1197 NQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTE-H 1255
             ++K++ E   +E   L   ++  ++ ++  +D+     +EL K+        + + + +
Sbjct: 2744 KEIKNQFETTKSEKIYLEKDISNAKTELNDLLDKNNKLESELRKKEREITRLSYSENKLN 2803

Query: 1256 ELRVQLSAFESKYEQLLDSVQSSTQE---ETNKIVTME-QVTSLQNKLQDKEEHLRNLQE 1311
            +L+++L+  +S+ +     ++  + E   ++ +I +      S + ++Q K + +++L+ 
Sbjct: 2804 DLQIELNKLKSEMKDKTSEIERLSNELSLKSEEIYSFSCSSNSFEKEIQTKSDKIKSLEN 2863

Query: 1312 KYADVIN---QIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQ-SI 1367
            +   V     QI+ L +++ ++ +                   L + N   K +Q   S+
Sbjct: 2864 EIKKVQKENEQIKDLENQLNEKSLIIENLQKEFKQKDEKHETVLNSMNDKMKGLQNDLSV 2923

Query: 1368 LN-INEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTIT 1426
            L+ +  EN ++ K +              +D   ++ +L++ L+  D E+    +     
Sbjct: 2924 LSDLQRENEKITKQNEEIKSQNKKLKEENDDKNREIKKLSNTLQKGDIEM----NTLKDL 2979

Query: 1427 LTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERV- 1485
            L  + ++  N    L + + ++ED  YE    +     K+++     E  Q++ E++ + 
Sbjct: 2980 LQTKEEKIRNYEDILEKTKTQMEDKNYEFSKTVKDQNDKINQLEKELE--QRDLELDDLT 3037

Query: 1486 ----KLIEELNVKITESVSLNKQVAELNKALE---EEVAKT-NEMQTALENQEIEIVTLN 1537
                   +E N KI    + NK + + N+ L+     V K+ NE++  + N E ++ + +
Sbjct: 3038 NKSKSFDDEKNDKIQSLTTENKNLKKENRTLKGIINSVKKSSNELEERIRNLESQLKSHS 3097

Query: 1538 DEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDN 1574
              +  LQ       SK+QK +    +  + ++E+L N
Sbjct: 3098 SSLIELQEKKETEISKLQKEIDEREEKIKSQNEKLSN 3134



 Score =  178 bits (434), Expect = 9e-43
 Identities = 293/1516 (19%), Positives = 664/1516 (43%), Gaps = 127/1516 (8%)

Query: 143  DVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXX 202
            D + +   + +++  +  L  K++ +  T   +++  +E+   +E +N+           
Sbjct: 2378 DNSTMKKVLTKQEKIIQKLNTKVEDLTETKQTMKQTQSEELSSLEEENEQKKEELKHLKE 2437

Query: 203  XXXXXXXXXEDTKQQMTKMQENFIAMEAEWKD-EKQRLLKDIESKDVRISSLEEANKLLE 261
                     +  ++ + K+ E   + + E ++  KQ+L+ D    +++ SS+ E  K LE
Sbjct: 2438 EFLEKEKRLKGLEKSIQKVTEKITSQKEEIENLRKQKLIDDNTISELK-SSISENEKELE 2496

Query: 262  AARFEISLEHS---KLAQELEQXXXXXXXXXXXXXXLAK--QSIEPSCEEKTEIEEKGSL 316
              R   S +     +L  E E               L K    I+   ++ ++ E+    
Sbjct: 2497 NLRKSDSDKSDIIEQLKSESENLSMSLKSRSNYENELTKLQNKIQKLNDQISDKEDDLKS 2556

Query: 317  EIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGR 376
            +   + +L KK++  E    + ++ NK ++++ A +  + +A+       +  I +    
Sbjct: 2557 KEILLEKLQKKVQETEEKFSETQKLNKTMKDENANISNQLRALQMELNSKTKQIEKLVKD 2616

Query: 377  NTASKMKSP---WSQLSSETLNQDTDKKI----NKNEIAKLEMVIQSLNKDLVDK-EYVI 428
            NT  K K     + Q + +  N++ ++KI    N N   K ++++    K  +D+ ++ I
Sbjct: 2617 NTNLKEKVTILEFKQSNFDDDNKEKEEKIENLENDNFNLKKQIILNEEYKKQIDELKFQI 2676

Query: 429  SEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQE 488
            S+ +            ++TL+    L+++  +           +E + E+ K++  L+Q+
Sbjct: 2677 SQLNYDNKEKVTRLQNENTLLKTKSLQNKSELNTVKKEREDLQSE-IEEL-KMKFDLEQK 2734

Query: 489  LNDEIKDVN--VKDLIEKLKSA----EEQI----TQLNDEIDAANKNMIKVKSNHKL--- 535
             N+ +K  N  +K+  E  KS     E+ I    T+LND +D  NK   +++   +    
Sbjct: 2735 ENENLKKQNKEIKNQFETTKSEKIYLEKDISNAKTELNDLLDKNNKLESELRKKEREITR 2794

Query: 536  ------KLKQMQKTIDNF-SKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHL-VD 587
                  KL  +Q  ++   S++ D   EI RL+ EL   S+++        + +  +   
Sbjct: 2795 LSYSENKLNDLQIELNKLKSEMKDKTSEIERLSNELSLKSEEIYSFSCSSNSFEKEIQTK 2854

Query: 588  YDSGRMIESDVYKKMIEMENLA--ETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLA 645
             D  + +E+++ K   E E +   E +L   SL+     +L +E     +K++ V + + 
Sbjct: 2855 SDKIKSLENEIKKVQKENEQIKDLENQLNEKSLIIE---NLQKEFKQKDEKHETVLNSMN 2911

Query: 646  D-ISQLQSD-QVCSEIKSVH--LEEQIDALSASKKELALVIENLKLDKEQLYGTIK--DL 699
            D +  LQ+D  V S+++  +  + +Q + + +  K+L    ++   + ++L  T++  D+
Sbjct: 2912 DKMKGLQNDLSVLSDLQRENEKITKQNEEIKSQNKKLKEENDDKNREIKKLSNTLQKGDI 2971

Query: 700  E-NDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQ 758
            E N  +D++   +  I+   D+ +K +    +K  E  +K   ++  KI     ++ +++
Sbjct: 2972 EMNTLKDLLQTKEEKIRNYEDILEKTKTQMEDKNYEF-SKTVKDQNDKINQ---LEKELE 3027

Query: 759  ERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTI 818
            +RDL ++++ +   K KS      + I  +     +L+++   L   +   +K+ +E   
Sbjct: 3028 QRDLELDDLTN---KSKSFDDEKNDKIQSLTTENKNLKKENRTLKGIINSVKKSSNEL-- 3082

Query: 819  QEDELVNRLAVLMDHD----RVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQ 874
             E+ + N  + L  H      + EK+  EI    KE+ ++ + +  +N+ L     ++++
Sbjct: 3083 -EERIRNLESQLKSHSSSLIELQEKKETEISKLQKEIDEREEKIKSQNEKLSNCRKEVEK 3141

Query: 875  HYNALVE-KANRTDLAESESTKYQTQLRDLESNLKRITHEHQTL---IVQKKKEIEDLEI 930
                + E KA        E    + +  DL   +K I  E   L   I   K+E +DL+ 
Sbjct: 3142 TKQEIEEMKAKLNSQLTEEIQTIKGEKEDLLEKIKSINKERDELSQQIKSLKRENDDLQQ 3201

Query: 931  EFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELN--KMNLEL 988
            +  + IE   + +K +N+  ++      ++E Q ++ K  IEN +  ++  N  K  L+ 
Sbjct: 3202 KLKSVIEEREKLEKEVNDLTQQIKSLKNEIEEQKEKSKKEIENFSEKLKSSNEEKQKLQN 3261

Query: 989  IDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKIN--NAQVSYMSMVS-- 1044
             +  +Q++     +  E    E + +N  LK + EE+  LN++I+   +Q+  +  V+  
Sbjct: 3262 QNDDLQQKLESIKEERENLKRENDLINKKLKSQSEELQKLNKEIDYSKSQIDSLDEVNKK 3321

Query: 1045 -----DYESK-----LAQFTTKLENMEEEMQRVSKQ---LLD-SKQHNEELQILVREQDD 1090
                 + E+K     + + TTK+ ++  E+++++ +   L+D +K+ NE+L   V + D+
Sbjct: 3322 LNSTNEQENKQLNDQINKLTTKVNDLNNEIKKLTSEKNDLIDQNKRLNEDLSKKVNQFDE 3381

Query: 1091 QIKELKET--KLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEE 1148
            + ++L E   +   E+N    +   + S    +  + N ++               Q+++
Sbjct: 3382 ETQKLNEQLKRSKEEINDINNQNKKLDSLNNDLKQENNKLNHEITKLNSLTNEFNEQKKK 3441

Query: 1149 -EFIQERSV-LQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQ- 1205
             + ++E ++ L   + +L  E +E   K+  L     E+T  +  NQ+QI+ L  KL + 
Sbjct: 3442 FDSVKEENLRLNSLNNELKQENEEISKKLKSLNEQIKEITNEN--NQDQIDLLNKKLNEN 3499

Query: 1206 ------LNTENDNL---LSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQ---KT 1253
                  LN + +NL   L    E    ++  V+    E+ E  KQ       D Q   +T
Sbjct: 3500 ETFTRKLNDDKENLAKKLQISNEENKKLNKKVEDLSEELEES-KQREENSLIDLQNKNET 3558

Query: 1254 EHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKY 1313
               L+ Q+   + + +++     +  QE  N  +   ++   QN++++++  + NLQ+  
Sbjct: 3559 LENLKTQIKKQKQQIQEINRENNNLKQELENSQI---EIDDFQNQIENQKLKIDNLQKV- 3614

Query: 1314 ADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDL-RTENQSYKQMQE--QSILNI 1370
               IN  +I++ E+++E +                  +  + E Q+ + +++  ++  +I
Sbjct: 3615 --TINNEKIIK-ELKNENLELKSLTSDLQLSLHSSQSEKEKIEKQNDENLRDLQKAKSDI 3671

Query: 1371 NEENAQLKKSS--XXXXXXXXXXXXRVNDAEAKVLELTHQLELKD---SEIYQKTHEYTI 1425
            ++    LK +S              + N  +   +  T  + ++D    EI Q   E   
Sbjct: 3672 SDLTKLLKNNSPQASIDNRRKFQISQTNTTDIAAVSGTFSV-MEDPISEEIEQLKDENNK 3730

Query: 1426 TLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERV 1485
                 + +  N+++     +  +E    EKE+ L   +L + E +N  +    +   + V
Sbjct: 3731 MKKDLSQKIRNLQKDNEFLKSELEKTKSEKENGLLGTKLSISEISNDNDVYLMKINNDLV 3790

Query: 1486 KLIEELNVKITESVSLNKQVAELNKALEE---EVAKTNEMQTALENQEIEIVTLNDEITN 1542
            K   EL ++I+     N+++ ++NK  ++   E+ +  +M+  +E +  ++   + E  N
Sbjct: 3791 KENSELKIRISLLEKENEEMKQINKEKKDRTSEMLREKDMRKRMEEELQKLRRSDKEKNN 3850

Query: 1543 LQNMVRASSSKIQKHV 1558
            L   ++      Q+ V
Sbjct: 3851 LIQRIKRKEETAQEEV 3866



 Score =  172 bits (418), Expect = 8e-41
 Identities = 265/1302 (20%), Positives = 572/1302 (43%), Gaps = 115/1302 (8%)

Query: 334  LNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLIS-RKSGRNTASKMKSPWSQLSSE 392
            LN ++ + +K+L++K     T  +  +   ++   +   +K+  +    +KS    L S+
Sbjct: 304  LNTKLMEADKKLKSKTKDFETLEQKYNVLLEQFHTINQEKKAAADQVEALKSQIKDLQSK 363

Query: 393  TLNQDTDKKINKNEIAKLEMVIQSLN---KDLVDKEYVISEKDTXXXXXXXXXXGKDTLI 449
            + N  +D K  +NEI KL+ + ++     +D+  K   +S+ +            ++   
Sbjct: 364  SANSSSDFKAKQNEIDKLKQINEAQKNFIEDIQRKYDELSQSNLNSPKERTNPFQQELEN 423

Query: 450  AQLQLEHQ---------QHMEGPSLIH-VGTNTEDVNEIAKVQEQLKQELNDEIKDVNVK 499
             + +L+ Q         Q+M   + I+ + +  ++  +     + +++E +  + + +++
Sbjct: 424  LRRRLQDQDKENKALTDQNMALNNQINFLKSQLQNSRQPLPSTQYMEEENSSNLDESDIQ 483

Query: 500  DLIEK---LKSAEEQITQLNDEI----DAANKN---MIKVKSNHKLKLKQMQKTIDNFSK 549
            +++E    +   E +I +LN+ I    +AA K      K+K  + L   + ++ +   S+
Sbjct: 484  NMLETNQVISDYENKIKELNETILSLRNAAPKTPDTSAKMKRENSLLKSENEELV---SR 540

Query: 550  VSDSNKEIVRLTEELHHLSQKVAELEEE-KGNLQ--LHLVDYDSGRMIESDVYKKMIEME 606
            V+   KE  +L  ++  L+ ++   +++  G++Q  L+++     ++     Y+     +
Sbjct: 541  VNQIKKENTQLKSDIQDLNNQLRNKKKDFAGSVQNQLNIIKLFLNKLFADFNYEIQKTKQ 600

Query: 607  NLAETRLKAISLLESQKFD-------LVQELHILQQKYDEVEDKLADI-SQLQSDQVCSE 658
             +++  L  +  L+ QK +       L ++++ L+Q+  +++DK+ D+ + LQ     +E
Sbjct: 601  KISDEFLTILRKLQQQKENETNKTKLLERQINDLKQENMKLKDKINDLQNNLQKILQENE 660

Query: 659  IKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLEND-KEDIMNKLQNYIQEN 717
              S  +   ID LS S KE    I   K   E L   IK  E D  ++  N ++   Q+ 
Sbjct: 661  NHSKQISTHIDGLSQSIKERDDQILKDKEKIENLQNKIKGKEIDFDQEKSNLIKQNEQKM 720

Query: 718  MDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSR 777
             DLTD++E +  + +   L  +  + Q + Q    ++ KI+E+D  I+ ++ ++++    
Sbjct: 721  KDLTDEMENLKRKLLDNELDVVKDQLQKEKQKSQDLEEKIEEKDSTIQILKEKINE---- 776

Query: 778  ICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVV 837
               LEES           ++  D+L   + +KQ+  +    Q +EL   +    +  +  
Sbjct: 777  --NLEES-----------KKSYDKL---MNDKQEEIALLQKQINELQELIKNNGESSKTK 820

Query: 838  EKQLL-EIEHENKELQKKNQILLEENQ---NLQISLSDMQQHYNALVEKANRTDLAESES 893
               LL E  + N ++Q+ N +L +++    +LQ  ++D+ Q+   L ++         +S
Sbjct: 821  ISSLLQENTNLNTKIQQLNSLLKQKDDKINDLQNEINDLTQNKIDLEKQIQNLQTIIFDS 880

Query: 894  TKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKN 953
                  L +  S L+++    Q  I     +I+  +IE     + A + +  +NE+ +K 
Sbjct: 881  KSQIESLNEKISGLQQLLKSSQETIDSLNDKIKQTQIELQESKDFAEKLQNDINEEKKKT 940

Query: 954  IEYVTQLEA--QLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEI 1011
             +Y  +L+   +L + +N ++    ++   N  N++ IDK ++ +  Q  D   Q    I
Sbjct: 941  EDYQLKLDDIDRLTKERNLLKETEKSLTLTNAENMQTIDK-LKDEIEQLNDKISQLNTTI 999

Query: 1012 NKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQL 1071
            ++LN ++ +KDEEI    QK   ++  + + ++DY+ +L     ++  +EEE++++SK+ 
Sbjct: 1000 DQLNDVISKKDEEIKQDLQKFELSEKVHQAAINDYQKQLEHHEEQITLLEEEIEKISKEN 1059

Query: 1072 LDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXX 1131
             D K    E +  + + DD  K+  E K   E    + E     S ++ +S++  N    
Sbjct: 1060 SDLKAKILENEAKLDDFDDVSKQNSEYKAKIEQ--LEEELADYESNLQKLSEENGN---- 1113

Query: 1132 XXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVV 1191
                      L++Q EE  I+ ++V      +L T+  +   +I +L+ L     G+  V
Sbjct: 1114 ----------LEIQIEE--IKLKTVPNTDFNELRTKNTDLEAQIRELKRLLANDDGNKQV 1161

Query: 1192 ---NQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREA 1248
                 ++I  L   +  L   N  L   + ++  +  +   +R F   EL  Q +     
Sbjct: 1162 IAQKDKEILSLNQTIIDLQHNNQLLNDKIKDIEMT-KTNYPERSFNNDEL-HQTIEDNNV 1219

Query: 1249 ---DFQKTEHELRVQLSAFESKYEQLLDSVQS--STQEETNKIVTMEQVTSLQNKLQDKE 1303
               D Q   +   ++L   E + + L + + S  S  EE N  + M     L+  L  KE
Sbjct: 1220 SMFDMQNKLNLANLKLKQSEKEIQNLKNELLSLQSENEEMNSTINM-----LKQSLTSKE 1274

Query: 1304 EHLRNLQEKYADVINQIE--ILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQ 1361
              +  L +      +QIE  + +++++ +K                   D+  E      
Sbjct: 1275 NEINELNDSVTVKNSQIEEILKKNQVKFDKTGNKEQQLQVLNSSLKHSNDIIQEKGKTID 1334

Query: 1362 MQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTH 1421
             Q + I N+ +   +L+K +              ND E    EL      K+  I Q   
Sbjct: 1335 SQNKLIKNLEDTKQKLQKQNFDLQNNVSNL---TNDLEKTKRELLSLQNSKNDNIKQLEQ 1391

Query: 1422 EYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKES- 1480
            E  + L Q+ +E +         E++I++LT +  +    +  K +E  N+ + +QK S 
Sbjct: 1392 EKELILKQKENENK-------ISEEKIKNLTLQISNLQNTISQKDNEIQNNLQNLQKVSN 1444

Query: 1481 EIERVK-LIEELNVKITESVSLNKQVAEL-NKALEEEVAKTNEMQTALENQEIEIVTLND 1538
            E++ +K   ++    +TE   +   + +L +  ++E   KT E Q +L  +++ I  L +
Sbjct: 1445 ELDFIKNSTKDHENDLTEKEDVINNLRKLFDDKMKENEKKTKEFQDSLREKDLMISQLEN 1504

Query: 1539 EITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKEL 1580
            +       +++   KI   +   + T QG  +++ N +   L
Sbjct: 1505 KTMFFDQQMKSKDDKIDS-LQIQNVTFQGELKEIQNKLINSL 1545



 Score =  165 bits (402), Expect = 7e-39
 Identities = 283/1467 (19%), Positives = 632/1467 (43%), Gaps = 113/1467 (7%)

Query: 148  SNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXX 207
            S+  K K N +  L+   +  +  I D+Q K    D++ ++   +               
Sbjct: 368  SSDFKAKQNEIDKLKQINEAQKNFIEDIQRKY---DELSQSNLNSPKERTNPFQQELENL 424

Query: 208  XXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEI 267
                +D  ++   + +  +A+  +    K +L    +         EE +  L+ +  + 
Sbjct: 425  RRRLQDQDKENKALTDQNMALNNQINFLKSQLQNSRQPLPSTQYMEEENSSNLDESDIQN 484

Query: 268  SLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKK 327
             LE +++  + E                A ++ + S + K E     SL  +   EL  +
Sbjct: 485  MLETNQVISDYENKIKELNETILSLRNAAPKTPDTSAKMKRE----NSLLKSENEELVSR 540

Query: 328  IELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWS 387
            +  ++  N Q++   ++L N+L     +             L   K   +   +++    
Sbjct: 541  VNQIKKENTQLKSDIQDLNNQLRNKKKDFAGSVQNQLNIIKLFLNKLFADFNYEIQKTKQ 600

Query: 388  QLSSETLNQDTDKKINK-NEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKD 446
            ++S E L      +  K NE  K +++ + +N DL  +   + +K             ++
Sbjct: 601  KISDEFLTILRKLQQQKENETNKTKLLERQIN-DLKQENMKLKDKINDL---------QN 650

Query: 447  TLIAQLQLEHQQHMEGPSLIHVGTNTEDVNE----IAKVQEQLKQELNDEIKDVNVKDLI 502
             L   LQ E++ H +  S  H+   ++ + E    I K +E++ + L ++IK   +    
Sbjct: 651  NLQKILQ-ENENHSKQIS-THIDGLSQSIKERDDQILKDKEKI-ENLQNKIKGKEIDFDQ 707

Query: 503  EK---LKSAEEQITQLNDEIDAANKNMIKVKSN-HKLKL-KQMQKTIDNFSKVSDSNKEI 557
            EK   +K  E+++  L DE++   + ++  + +  K +L K+ QK+ D   K+ + +  I
Sbjct: 708  EKSNLIKQNEQKMKDLTDEMENLKRKLLDNELDVVKDQLQKEKQKSQDLEEKIEEKDSTI 767

Query: 558  VRLTEELHHLSQKVAELEEEKGNLQLHLVD-YDSGRMIESDVYKKMIEMENLAETRLKAI 616
              L E+++        LEE K +    + D  +   +++  + +    ++N  E+    I
Sbjct: 768  QILKEKINE------NLEESKKSYDKLMNDKQEEIALLQKQINELQELIKNNGESSKTKI 821

Query: 617  SLLESQKFDL---VQELH-ILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALS 672
            S L  +  +L   +Q+L+ +L+QK D++ D   +I+ L  +++  E +  +L+     + 
Sbjct: 822  SSLLQENTNLNTKIQQLNSLLKQKDDKINDLQNEINDLTQNKIDLEKQIQNLQ---TIIF 878

Query: 673  ASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEK-MSAEK 731
             SK ++  + E +    +QL  + ++  +   D + + Q  +QE+ D  +KL+  ++ EK
Sbjct: 879  DSKSQIESLNEKIS-GLQQLLKSSQETIDSLNDKIKQTQIELQESKDFAEKLQNDINEEK 937

Query: 732  ISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDR 791
                  ++  ++  ++  +  +  K  E+ L + N E+        I +L++ I  + D+
Sbjct: 938  KKTEDYQLKLDDIDRLTKERNL-LKETEKSLTLTNAEN-----MQTIDKLKDEIEQLNDK 991

Query: 792  RYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKEL 851
               L    DQL   + +K +   +  +Q+ EL  ++     +D   +KQL   E +   L
Sbjct: 992  ISQLNTTIDQLNDVISKKDEEIKQ-DLQKFELSEKVHQAAIND--YQKQLEHHEEQITLL 1048

Query: 852  QKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRIT 911
            +++ + + +EN +L+  + + +   +   + + +    +++  + + +L D ESNL++++
Sbjct: 1049 EEEIEKISKENSDLKAKILENEAKLDDFDDVSKQNSEYKAKIEQLEEELADYESNLQKLS 1108

Query: 912  HEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNI 971
             E+  L +Q    IE+++++     +         NE   KN    T LEAQ++E K  +
Sbjct: 1109 EENGNLEIQ----IEEIKLKTVPNTD--------FNELRTKN----TDLEAQIRELKRLL 1152

Query: 972  ENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQK 1031
             N + N + + + + E++  +   Q      +  Q +N+  K   + K    E    N +
Sbjct: 1153 ANDDGNKQVIAQKDKEILSLN---QTIIDLQHNNQLLNDKIKDIEMTKTNYPERSFNNDE 1209

Query: 1032 INNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQ--ILVREQD 1089
            ++         + D ++KL     KL+  E+E+Q +  +LL  +  NEE+   I + +Q 
Sbjct: 1210 LHQTIEDNNVSMFDMQNKLNLANLKLKQSEKEIQNLKNELLSLQSENEEMNSTINMLKQS 1269

Query: 1090 DQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEE 1149
               KE +  +L   + +  ++   I    +   D   N +              ++   +
Sbjct: 1270 LTSKENEINELNDSVTVKNSQIEEILKKNQVKFDKTGNKEQQLQVLNS-----SLKHSND 1324

Query: 1150 FIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQL-NT 1208
             IQE+    +   KL   L++   K   L+  N +L  +       + + K +L  L N+
Sbjct: 1325 IIQEKGKTIDSQNKLIKNLEDTKQK---LQKQNFDLQNNVSNLTNDLEKTKRELLSLQNS 1381

Query: 1209 ENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKT----EHELRVQLSAF 1264
            +NDN+     E    +    ++   +I+E   ++L  + ++ Q T    ++E++  L   
Sbjct: 1382 KNDNIKQLEQEKELILKQKENEN--KISEEKIKNLTLQISNLQNTISQKDNEIQNNLQNL 1439

Query: 1265 ESKYEQLLDSVQSSTQEETNKIVTMEQV-TSLQNKLQDKEEHLRNLQEKYADVINQIEIL 1323
            + K    LD +++ST++  N +   E V  +L+    DK +      +++ D + + +++
Sbjct: 1440 Q-KVSNELDFIKNSTKDHENDLTEKEDVINNLRKLFDDKMKENEKKTKEFQDSLREKDLM 1498

Query: 1324 RSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXX 1383
             S++E++ + F                   T     K++Q + ++N  ++  +L+K +  
Sbjct: 1499 ISQLENKTMFFDQQMKSKDDKIDSLQIQNVTFQGELKEIQNK-LINSLKQIDELQKENES 1557

Query: 1384 XXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVE 1443
                       ++D+  ++ EL  +++  + EI  K  E    L  + + +EN  +   E
Sbjct: 1558 FQKELQTRDQNLDDSHKQIEELQAKIDQYEEEIKSK-DENLNNLQNKINNYENESKTNNE 1616

Query: 1444 YEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKL-----IEELNVKITES 1498
              K +E    +K +EL I  L+ + +    E  Q +SE+E+++       ++LN    ES
Sbjct: 1617 KIKEMEG--KQKSNELQINDLQNNVSQTENENKQLKSELEKLQTEIKSKSDQLNEIQNES 1674

Query: 1499 VSLNKQVA-------ELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASS 1551
             S ++Q+        EL   L   + + +E+Q   E+ + E+ T +  + +    +    
Sbjct: 1675 KSQSEQIVTFQGELKELQNKLTSSLKQIDELQKENESFQKELQTRDQNLDDSHKQIEELQ 1734

Query: 1552 SKIQKHVSFASDTKQGRDEQLDNTMNK 1578
            +KI ++     +  + +DE L+N  NK
Sbjct: 1735 AKIDQY----EEEIKSKDENLNNLQNK 1757



 Score =  163 bits (397), Expect = 3e-38
 Identities = 301/1473 (20%), Positives = 613/1473 (41%), Gaps = 135/1473 (9%)

Query: 175  LQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQ----ENF----- 225
            LQ ++N K + IE   K  T                 +D K++  K++    +NF     
Sbjct: 2599 LQMELNSKTKQIEKLVKDNTNLKEKVTILEFKQSNFDDDNKEKEEKIENLENDNFNLKKQ 2658

Query: 226  IAMEAEWKDEKQRLLKDIESKDV----RISSLEEANKLLEAARFE-------ISLEHSKL 274
            I +  E+K +   L   I   +     +++ L+  N LL+    +       +  E   L
Sbjct: 2659 IILNEEYKKQIDELKFQISQLNYDNKEKVTRLQNENTLLKTKSLQNKSELNTVKKEREDL 2718

Query: 275  AQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLE--IANM-TELTKKIELL 331
              E+E+              L KQ+ E   + +T   EK  LE  I+N  TEL   ++  
Sbjct: 2719 QSEIEELKMKFDLEQKENENLKKQNKEIKNQFETTKSEKIYLEKDISNAKTELNDLLDKN 2778

Query: 332  EHLNCQIRQTNKEL------ENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSP 385
              L  ++R+  +E+      ENKL  +  E   + S  K  +  I R S   +    +  
Sbjct: 2779 NKLESELRKKEREITRLSYSENKLNDLQIELNKLKSEMKDKTSEIERLSNELSLKSEEIY 2838

Query: 386  WSQLSSETLNQDTDKKINKNEIAKLEMV-IQSLNKDLVDKEYVISEKDTXXXXXXXXXXG 444
                SS +  ++   K +K +  + E+  +Q  N+ + D E  ++EK             
Sbjct: 2839 SFSCSSNSFEKEIQTKSDKIKSLENEIKKVQKENEQIKDLENQLNEKSLIIENLQKEFKQ 2898

Query: 445  KDTLIAQLQLEHQQHMEG-PSLIHVGTNTEDVNE-IAKVQEQLKQE---LNDEIKDVN-- 497
            KD     +       M+G  + + V ++ +  NE I K  E++K +   L +E  D N  
Sbjct: 2899 KDEKHETVLNSMNDKMKGLQNDLSVLSDLQRENEKITKQNEEIKSQNKKLKEENDDKNRE 2958

Query: 498  VKDLIEKLKSAEEQITQLNDEIDAANKN-------MIKVKSNHKLKLKQMQKTI-DNFSK 549
            +K L   L+  + ++  L D +    +        + K K+  + K  +  KT+ D   K
Sbjct: 2959 IKKLSNTLQKGDIEMNTLKDLLQTKEEKIRNYEDILEKTKTQMEDKNYEFSKTVKDQNDK 3018

Query: 550  VSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMI----EM 605
            ++   KE+ +   EL  L+ K    ++EK +    L   +     E+   K +I    + 
Sbjct: 3019 INQLEKELEQRDLELDDLTNKSKSFDDEKNDKIQSLTTENKNLKKENRTLKGIINSVKKS 3078

Query: 606  ENLAETRLKAI-SLLESQKFDLVQ-------ELHILQQKYDEVEDKLADISQLQSD---- 653
             N  E R++ + S L+S    L++       E+  LQ++ DE E+K+   ++  S+    
Sbjct: 3079 SNELEERIRNLESQLKSHSSSLIELQEKKETEISKLQKEIDEREEKIKSQNEKLSNCRKE 3138

Query: 654  -----QVCSEIKSV---HLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKED 705
                 Q   E+K+     L E+I  +   K++L   I+++  ++++L   IK L+ + +D
Sbjct: 3139 VEKTKQEIEEMKAKLNSQLTEEIQTIKGEKEDLLEKIKSINKERDELSQQIKSLKRENDD 3198

Query: 706  IMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIE 765
            +  KL++ I+E     +KLEK   +   ++ +  N  E+ K +++  I+    E+   ++
Sbjct: 3199 LQQKLKSVIEER----EKLEKEVNDLTQQIKSLKNEIEEQKEKSKKEIE-NFSEK---LK 3250

Query: 766  NIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVN 825
            +   E  K +++   L++ +  +++ R +L+R+ D +   L+ + +   +   + D   +
Sbjct: 3251 SSNEEKQKLQNQNDDLQQKLESIKEERENLKRENDLINKKLKSQSEELQKLNKEIDYSKS 3310

Query: 826  RLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANR 885
            ++  L   D V +K     E ENK+L  +   L  +  +L   +  +    N L+++  R
Sbjct: 3311 QIDSL---DEVNKKLNSTNEQENKQLNDQINKLTTKVNDLNNEIKKLTSEKNDLIDQNKR 3367

Query: 886  TDLAESEST-KYQTQLRDLESNLKRITHEHQTLIVQKKKEIE---DLEIEFN------TQ 935
             +   S+   ++  + + L   LKR   E   +  Q KK      DL+ E N      T+
Sbjct: 3368 LNEDLSKKVNQFDEETQKLNEQLKRSKEEINDINNQNKKLDSLNNDLKQENNKLNHEITK 3427

Query: 936  IESAIRD----KKVLNEKYEKNIEYVT---QLEAQLQEYKNNIENLNMNVEEL-NKMNLE 987
            + S   +    KK  +   E+N+   +   +L+ + +E    +++LN  ++E+ N+ N +
Sbjct: 3428 LNSLTNEFNEQKKKFDSVKEENLRLNSLNNELKQENEEISKKLKSLNEQIKEITNENNQD 3487

Query: 988  LIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYE 1047
             ID  + K+  ++  +T +  ++   L   L+  +EE   LN+K+ +            E
Sbjct: 3488 QIDL-LNKKLNENETFTRKLNDDKENLAKKLQISNEENKKLNKKVEDLSEELEESKQREE 3546

Query: 1048 SKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIP 1107
            + L     K E +E    ++ KQ    ++ N E   L +E ++   E+ + +   E    
Sbjct: 3547 NSLIDLQNKNETLENLKTQIKKQKQQIQEINRENNNLKQELENSQIEIDDFQNQIENQKL 3606

Query: 1108 KTEGM-IISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNT 1166
            K + +  ++   E +  +  N +            L +   +    E+  +++Q+ +   
Sbjct: 3607 KIDNLQKVTINNEKIIKELKN-ENLELKSLTSDLQLSLHSSQ---SEKEKIEKQNDENLR 3662

Query: 1167 ELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLS-TVAELRSSIS 1225
            +LQ+  + I  L    T+L  ++       N+ K ++ Q NT +   +S T + +   IS
Sbjct: 3663 DLQKAKSDISDL----TKLLKNNSPQASIDNRRKFQISQTNTTDIAAVSGTFSVMEDPIS 3718

Query: 1226 SAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEET-- 1283
              ++Q   E  ++ K+ L+Q+  + QK    L+ +L   +S+ E  L   + S  E +  
Sbjct: 3719 EEIEQLKDENNKM-KKDLSQKIRNLQKDNEFLKSELEKTKSEKENGLLGTKLSISEISND 3777

Query: 1284 ---------NKIVTMEQVTSLQNKLQDKE-EHLRNLQEKYADVINQI---EILRSEIEDE 1330
                     N +V       ++  L +KE E ++ + ++  D  +++   + +R  +E+E
Sbjct: 3778 NDVYLMKINNDLVKENSELKIRISLLEKENEEMKQINKEKKDRTSEMLREKDMRKRMEEE 3837

Query: 1331 KVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSIL---NINEENAQLKKSSXXXXXX 1387
                                   T  +  ++++E+ I+     +E+NA  +K S      
Sbjct: 3838 LQKLRRSDKEKNNLIQRIKRKEETAQEEVRKVKEEMIILKKVCDEKNAAFEKLSEEHKMI 3897

Query: 1388 XXXXXXRVNDAEAKVLE-LTHQLELKDSE-----IYQK-THEYTITLTQRNDEFENVRQQ 1440
                  R N++  +  E L  +LE   +E      Y K   E    L    +  +N + +
Sbjct: 3898 LNSLKGRNNESILEENERLKEELENARNESVSNDSYLKINEEVEKNLQTALESLQNAKDE 3957

Query: 1441 LVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVS 1500
                 K+++    E +S   I++      ++ +E      + E  KL +E       +  
Sbjct: 3958 NERLTKKLQKTERENKSLKQIIKSSEDLKSSEFEEEIDNLKTEVKKLRKEKKSFTNVASK 4017

Query: 1501 LNKQVAELNKALEEEVAKTNEMQTALENQEIEI 1533
            + K++ +L K +   V   N+   + EN   EI
Sbjct: 4018 MEKKIDKLTKTVTGVVEIVNKYSDSSENPTQEI 4050



 Score =  159 bits (386), Expect = 6e-37
 Identities = 249/1348 (18%), Positives = 577/1348 (42%), Gaps = 109/1348 (8%)

Query: 295  LAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIEL----LEHLNCQIRQTNKELENKLA 350
            + KQS+     E  E+ +  +++ + + E+ KK ++      +   Q++  N  L++   
Sbjct: 1265 MLKQSLTSKENEINELNDSVTVKNSQIEEILKKNQVKFDKTGNKEQQLQVLNSSLKHSND 1324

Query: 351  TMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKL 410
             +  + K + S +K    LI  K+  +T  K++     L +   N   D +  K E+  L
Sbjct: 1325 IIQEKGKTIDSQNK----LI--KNLEDTKQKLQKQNFDLQNNVSNLTNDLEKTKRELLSL 1378

Query: 411  EMVIQSLNKDLV-DKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVG 469
            +       K L  +KE ++ +K+                I+ LQ    Q  +   + +  
Sbjct: 1379 QNSKNDNIKQLEQEKELILKQKENENKISEEKIKNLTLQISNLQNTISQ--KDNEIQNNL 1436

Query: 470  TNTEDV-NEIAKVQEQLKQELND--EIKDV--NVKDLIE-KLKSAEEQITQLNDEIDAAN 523
             N + V NE+  ++   K   ND  E +DV  N++ L + K+K  E++  +  D +   +
Sbjct: 1437 QNLQKVSNELDFIKNSTKDHENDLTEKEDVINNLRKLFDDKMKENEKKTKEFQDSLREKD 1496

Query: 524  KNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNK----EIVRLTEELHHLSQKVAELEEEKG 579
              + ++++      +QM+   D    +   N     E+  +  +L +  +++ EL++E  
Sbjct: 1497 LMISQLENKTMFFDQQMKSKDDKIDSLQIQNVTFQGELKEIQNKLINSLKQIDELQKENE 1556

Query: 580  NLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDE 639
            + Q  L   D       D +K++ E++   +   + I   +    +L  +++  + +   
Sbjct: 1557 SFQKELQTRDQNL---DDSHKQIEELQAKIDQYEEEIKSKDENLNNLQNKINNYENESKT 1613

Query: 640  VEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDL 699
              +K   I +++  Q  +E++   L+  +       K+L   +E L+ + +     + ++
Sbjct: 1614 NNEK---IKEMEGKQKSNELQINDLQNNVSQTENENKQLKSELEKLQTEIKSKSDQLNEI 1670

Query: 700  ENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQE 759
            +N+ +    ++  +  E  +L +KL   S ++I EL  K N   Q ++QT+   D  + +
Sbjct: 1671 QNESKSQSEQIVTFQGELKELQNKLTS-SLKQIDEL-QKENESFQKELQTR---DQNLDD 1725

Query: 760  RDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQ 819
                IE +++++ +Y+  I   +E++  ++++  + E ++      ++E +       +Q
Sbjct: 1726 SHKQIEELQAKIDQYEEEIKSKDENLNNLQNKINNYENESKTNNEKIKEMEGKQKSNELQ 1785

Query: 820  EDELVNRLAVLMDHDRVVEK--------------QLLEIEHENKELQKKNQILLEENQNL 865
             ++L N ++   + ++ ++               QL EI++E+K   ++     +E ++ 
Sbjct: 1786 INDLQNNVSQTENENKQLKSELEKLQTEIKSKSDQLNEIQNESKSQSEQIVTFQDEVKSK 1845

Query: 866  QISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEI 925
               L   ++    L  K N  + +       Q QL D E  L  +   ++ L+    K++
Sbjct: 1846 DEKLQTQEEQIKELENKLNELENSLRNKGDLQVQLNDREKELNNLKKVNENLV----KQV 1901

Query: 926  EDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMN 985
            EDL++           +K+  ++K  +N E +T L     + K   E L  N +E N+  
Sbjct: 1902 EDLQV-----------NKEQSDKKLSENDEELTNLRRNNADLKKQNEKLREN-KEKNESE 1949

Query: 986  LELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKI--NNAQVSYMSMV 1043
            +  +   + +      D       ++ + N+++KQ++ +I  L Q++   N  +  +  +
Sbjct: 1950 IISLQNRLSELTNSHNDELFTVKRKLEENNSIVKQQNAKIEMLKQQLIDQNKTIEDLQKI 2009

Query: 1044 SDYESKLAQFTTKLENMEEEMQRVSKQL-LDSKQHNEELQILVREQDDQIKELKETKLTF 1102
             +    L    + L+     +++V++   L +K+ NE+L   + +  +++KE +++    
Sbjct: 2010 INESENLQFLVSTLKTENNTLKKVTQDNDLQNKKTNEDLLSQINDLQNKLKETEKSSQIQ 2069

Query: 1103 EMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXL-KVQEEEEFIQERSVLQEQS 1161
            +         I S   + + D+++ +D            L + Q+++  ++++  +  + 
Sbjct: 2070 KSKYESQLNEIQSKLNQSIKDNSDLMDKHENELKNLDEKLQESQKQKNDLEKKFEMNSKL 2129

Query: 1162 AKLNTEL-QECYTKIIQLETLNTELTGHDVVNQEQINQL-KSKLEQ---LNTENDNLLST 1216
               N +L QE + K   LE L T +   +   +EQI+ L K K E    LNT  +N    
Sbjct: 2130 LNENNKLRQEKFDK--TLEEL-TNVKSENGKLKEQIDDLEKEKNEMTILLNTTQNNQNED 2186

Query: 1217 VAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQ 1276
            +  L+  +++ +D+            L     D+   + +   +L+        L+ S++
Sbjct: 2187 LQNLQKKLNATIDE------------LKMTTNDYNSLKEKFE-KLNGKSDNDNSLISSLK 2233

Query: 1277 SSTQEETNKI-VTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFX 1335
                +  N +  T E+  SL  KL + E+ +  LQ+   ++  ++  +  E E+ ++   
Sbjct: 2234 RENDKMKNDLQKTQEENKSLVLKLNENEKTISKLQKTNDEISRKLTFV--ETENGELKLT 2291

Query: 1336 XXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRV 1395
                           + +    S  Q Q + + N N+      KS             ++
Sbjct: 2292 VNEMDEKVTTNETNSNEKERLISNLQKQNKQLENENKTLQSEIKSLQTDEFVKDQMKKQL 2351

Query: 1396 NDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEK 1455
            ND E KV +L  +     +E+  K  +   T+ +   + E + Q+L     ++EDLT  K
Sbjct: 2352 NDYEQKVSKLEDEKRQLQNEM-TKYKDDNSTMKKVLTKQEKIIQKL---NTKVEDLTETK 2407

Query: 1456 ES-------ELAILRLKMHENANHYETMQKE--SEIERVKLIEELNVKITESVSLNK-QV 1505
            ++       EL+ L  +  +     + +++E   + +R+K +E+   K+TE ++  K ++
Sbjct: 2408 QTMKQTQSEELSSLEEENEQKKEELKHLKEEFLEKEKRLKGLEKSIQKVTEKITSQKEEI 2467

Query: 1506 AELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTK 1565
              L K    +    +E+++++   E E+  L    ++  +++    S+  +++S +  ++
Sbjct: 2468 ENLRKQKLIDDNTISELKSSISENEKELENLRKSDSDKSDIIEQLKSE-SENLSMSLKSR 2526

Query: 1566 QGRDEQLDNTMNK--ELLDAVPRAELDL 1591
               + +L    NK  +L D +   E DL
Sbjct: 2527 SNYENELTKLQNKIQKLNDQISDKEDDL 2554



 Score =  139 bits (336), Expect = 7e-31
 Identities = 272/1292 (21%), Positives = 545/1292 (42%), Gaps = 128/1292 (9%)

Query: 313  KGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISR 372
            K +L I N  +  K+IE L HLN +++Q N+E E+ +      S+  S  +   + +   
Sbjct: 227  KSNLNIQNNADNLKEIEDLRHLNQELQQKNREQESLI------SQRTSELADARNEIFKL 280

Query: 373  KSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKD 432
               +NT S +KS         + QDT+ K     +A+L   +   +K L  K      KD
Sbjct: 281  SQNQNTESPIKS---------ILQDTESK-----VAELNTKLMEADKKLKSK-----TKD 321

Query: 433  TXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIH-VGTNTEDV-NEIAKVQEQLKQELN 490
                         + L+ Q    +Q+       +  + +  +D+ ++ A      K + N
Sbjct: 322  FETLEQKY-----NVLLEQFHTINQEKKAAADQVEALKSQIKDLQSKSANSSSDFKAKQN 376

Query: 491  DEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNF-SK 549
            +  K   +K + E  K+  E I +  DE+  +N N  K ++N        Q+ ++N   +
Sbjct: 377  EIDK---LKQINEAQKNFIEDIQRKYDELSQSNLNSPKERTN------PFQQELENLRRR 427

Query: 550  VSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIE--MEN 607
            + D +KE   LT++   L+ ++  L   K  LQ       S + +E +    + E  ++N
Sbjct: 428  LQDQDKENKALTDQNMALNNQINFL---KSQLQNSRQPLPSTQYMEEENSSNLDESDIQN 484

Query: 608  LAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQ 667
            + ET  + IS  E++  +L + +  L+    +  D  A + +       S +KS + EE 
Sbjct: 485  MLETN-QVISDYENKIKELNETILSLRNAAPKTPDTSAKMKREN-----SLLKSEN-EEL 537

Query: 668  IDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENM-DLTDKLEK 726
            +  ++  KKE   +  +++    QL    KD     ++ +N ++ ++ +   D   +++K
Sbjct: 538  VSRVNQIKKENTQLKSDIQDLNNQLRNKKKDFAGSVQNQLNIIKLFLNKLFADFNYEIQK 597

Query: 727  MSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESI- 785
             + +KIS+    I  + Q + + +     K+ ER   I +++ E  K K +I  L+ ++ 
Sbjct: 598  -TKQKISDEFLTILRKLQQQKENETN-KTKLLERQ--INDLKQENMKLKDKINDLQNNLQ 653

Query: 786  -AVMEDRRYS--LERKADQLGSYLQEKQKAYSEYTIQEDELVNRL-AVLMDHDRVVEKQL 841
              + E+  +S  +    D L   ++E+     +   + + L N++    +D D+     +
Sbjct: 654  KILQENENHSKQISTHIDGLSQSIKERDDQILKDKEKIENLQNKIKGKEIDFDQEKSNLI 713

Query: 842  LEIEHENKEL-----QKKNQILLEENQNLQISLSDMQQHYNALVEKANRTD-LAESESTK 895
             + E + K+L       K ++L  E   ++  L   +Q    L EK    D   +    K
Sbjct: 714  KQNEQKMKDLTDEMENLKRKLLDNELDVVKDQLQKEKQKSQDLEEKIEEKDSTIQILKEK 773

Query: 896  YQTQLRDLESNLKRITHEHQTLIVQKKKEIEDL-EIEFNTQIESAIRDKKVLNEKYEKNI 954
                L + + +  ++ ++ Q  I   +K+I +L E+  N    S  +   +L E    N 
Sbjct: 774  INENLEESKKSYDKLMNDKQEEIALLQKQINELQELIKNNGESSKTKISSLLQENTNLNT 833

Query: 955  EYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQT---QSPDYTEQYINEI 1011
            + + QL + L++  + I +L   + +L +  ++L +K +Q  QT    S    E    +I
Sbjct: 834  K-IQQLNSLLKQKDDKINDLQNEINDLTQNKIDL-EKQIQNLQTIIFDSKSQIESLNEKI 891

Query: 1012 NKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLA----QFTTKLENME---EEM 1064
            + L  LLK   E I +LN KI   Q+  +    D+  KL     +   K E+ +   +++
Sbjct: 892  SGLQQLLKSSQETIDSLNDKIKQTQIE-LQESKDFAEKLQNDINEEKKKTEDYQLKLDDI 950

Query: 1065 QRVSKQ--LLDSKQH-----NEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISST 1117
             R++K+  LL   +      N E    + +  D+I++L +        I +    +IS  
Sbjct: 951  DRLTKERNLLKETEKSLTLTNAENMQTIDKLKDEIEQLNDKISQLNTTIDQLND-VISKK 1009

Query: 1118 IEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQ 1177
             E +  D    +             + Q E    ++ ++L+E+  K++ E  +   KI++
Sbjct: 1010 DEEIKQDLQKFELSEKVHQAAINDYQKQLEHH-EEQITLLEEEIEKISKENSDLKAKILE 1068

Query: 1178 LETLNTELTGHDVVNQEQINQLKSKLEQLNTE---NDNLLSTVAELRSSISSAVDQRGFE 1234
             E    +L   D V+ +Q ++ K+K+EQL  E    ++ L  ++E   ++   +++   +
Sbjct: 1069 NE---AKLDDFDDVS-KQNSEYKAKIEQLEEELADYESNLQKLSEENGNLEIQIEEIKLK 1124

Query: 1235 -IAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVT 1293
             +       L  +  D +    EL+ +L A +   +Q++             I+ ++   
Sbjct: 1125 TVPNTDFNELRTKNTDLEAQIRELK-RLLANDDGNKQVIAQKDKEILSLNQTIIDLQHNN 1183

Query: 1294 SLQN-KLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDL 1352
             L N K++D E    N  E+     N  E L   IED  V+                  L
Sbjct: 1184 QLLNDKIKDIEMTKTNYPER---SFNNDE-LHQTIEDNNVSM-----------FDMQNKL 1228

Query: 1353 RTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELK 1412
               N   KQ  E+ I N+  E   L+  +             +   E ++ EL   + +K
Sbjct: 1229 NLANLKLKQ-SEKEIQNLKNELLSLQSENEEMNSTINMLKQSLTSKENEINELNDSVTVK 1287

Query: 1413 DSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANH 1472
            +S+I +   +  +   +  ++ E   Q L    K   D+  EK   +      +    + 
Sbjct: 1288 NSQIEEILKKNQVKFDKTGNK-EQQLQVLNSSLKHSNDIIQEKGKTIDSQNKLIKNLEDT 1346

Query: 1473 YETMQKES-EIER--VKLIEELNVKITESVSLNKQVAELNKALEEE---VAKTNEMQTAL 1526
             + +QK++ +++     L  +L     E +SL     +  K LE+E   + K  E +  +
Sbjct: 1347 KQKLQKQNFDLQNNVSNLTNDLEKTKRELLSLQNSKNDNIKQLEQEKELILKQKENENKI 1406

Query: 1527 ENQEIEIVTLNDEITNLQNMVRASSSKIQKHV 1558
              ++I+ +TL  +I+NLQN +    ++IQ ++
Sbjct: 1407 SEEKIKNLTL--QISNLQNTISQKDNEIQNNL 1436



 Score =  105 bits (253), Expect = 8e-21
 Identities = 151/788 (19%), Positives = 334/788 (42%), Gaps = 77/788 (9%)

Query: 806  LQEKQKAYSEY-TIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQIL--LEEN 862
            ++ ++ A   Y  +Q++ELV   + L+D    ++ +L      N  +Q     L  +E+ 
Sbjct: 186  IEMRRTASERYGRLQQEELVQENSQLLDRIEALQNELNNSNKSNLNIQNNADNLKEIEDL 245

Query: 863  QNLQISLSDMQQHYNALVEKANRTDLAESESTKYQ-TQLRDLESNLKRITHEHQTLIVQK 921
            ++L   L    +   +L+ +   ++LA++ +  ++ +Q ++ ES +K I  + ++    K
Sbjct: 246  RHLNQELQQKNREQESLISQ-RTSELADARNEIFKLSQNQNTESPIKSILQDTES----K 300

Query: 922  KKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEEL 981
              E+    +E + +++S  +D + L +KY   +E    +  + +   + +E L   +++L
Sbjct: 301  VAELNTKLMEADKKLKSKTKDFETLEQKYNVLLEQFHTINQEKKAAADQVEALKSQIKDL 360

Query: 982  NKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMS 1041
                         K    S D+  +  NEI+K    LKQ +E   A    I + Q  Y  
Sbjct: 361  Q-----------SKSANSSSDFKAKQ-NEIDK----LKQINE---AQKNFIEDIQRKYDE 401

Query: 1042 MVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLT 1101
            +    +S L     +    ++E++ + ++L D  + N+ L       ++QI  LK     
Sbjct: 402  L---SQSNLNSPKERTNPFQQELENLRRRLQDQDKENKALTDQNMALNNQINFLKSQLQN 458

Query: 1102 FEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQS 1161
                +P T+ M          ++++N+D            + + + E  I+E   L E  
Sbjct: 459  SRQPLPSTQYM--------EEENSSNLDESDIQNMLETNQV-ISDYENKIKE---LNETI 506

Query: 1162 AKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELR 1221
              L     +      +++  N+ L   +     ++NQ+K +  QL ++  +L + +   +
Sbjct: 507  LSLRNAAPKTPDTSAKMKRENSLLKSENEELVSRVNQIKKENTQLKSDIQDLNNQLRNKK 566

Query: 1222 SSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQE 1281
               + +V Q    I +L+   L    ADF    +E++        ++  +L  +Q   + 
Sbjct: 567  KDFAGSV-QNQLNIIKLFLNKLF---ADF---NYEIQKTKQKISDEFLTILRKLQQQKEN 619

Query: 1282 ETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXX 1341
            ETNK   +E+      ++ D ++    L++K  D+ N ++ +  E E+            
Sbjct: 620  ETNKTKLLER------QINDLKQENMKLKDKINDLQNNLQKILQENENHSKQISTHIDGL 673

Query: 1342 XXXXXXXXXDLRTENQSYKQMQEQ---SILNINEENAQLKKSSXXXXXXXXXXXXRVN-- 1396
                      +  + +  + +Q +     ++ ++E + L K +             +   
Sbjct: 674  SQSIKERDDQILKDKEKIENLQNKIKGKEIDFDQEKSNLIKQNEQKMKDLTDEMENLKRK 733

Query: 1397 --DAEAKVLELTHQLE-LKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTY 1453
              D E  V++   Q E  K  ++ +K  E   T+       E + + L E +K  + L  
Sbjct: 734  LLDNELDVVKDQLQKEKQKSQDLEEKIEEKDSTIQILK---EKINENLEESKKSYDKLMN 790

Query: 1454 EKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALE 1513
            +K+ E+A+L+ +++E     E ++   E  + K+   L     E+ +LN ++ +LN  L+
Sbjct: 791  DKQEEIALLQKQINE---LQELIKNNGESSKTKISSLLQ----ENTNLNTKIQQLNSLLK 843

Query: 1514 EEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQ---KHVSFASDTKQGRDE 1570
            ++  K N++Q  + +     + L  +I NLQ ++  S S+I+   + +S      +   E
Sbjct: 844  QKDDKINDLQNEINDLTQNKIDLEKQIQNLQTIIFDSKSQIESLNEKISGLQQLLKSSQE 903

Query: 1571 QLDNTMNK 1578
             +D+  +K
Sbjct: 904  TIDSLNDK 911



 Score = 64.5 bits (150), Expect = 2e-08
 Identities = 122/613 (19%), Positives = 251/613 (40%), Gaps = 72/613 (11%)

Query: 1008 INEINKLNALLKQKDEEIIALN-QKINNAQVSYMSMVSDYESKLAQFTT-KLENMEEEMQ 1065
            I++I++L+ L + K+  ++ +    I+  Q S + ++      L Q T   ++N+  EM+
Sbjct: 134  ISDISELHKLTECKNLTLLDIEGTPISRDQSSELYLIYI----LPQLTVINMKNITIEMR 189

Query: 1066 RVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSD-- 1123
            R + +     Q  E    LV+E    +  ++   L  E+N      + I +  + + +  
Sbjct: 190  RTASERYGRLQQEE----LVQENSQLLDRIEA--LQNELNNSNKSNLNIQNNADNLKEIE 243

Query: 1124 DANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTE------LQECYTKIIQ 1177
            D  +++            L  Q   E    R+ + + S   NTE      LQ+  +K+ +
Sbjct: 244  DLRHLNQELQQKNREQESLISQRTSELADARNEIFKLSQNQNTESPIKSILQDTESKVAE 303

Query: 1178 LETLNTELTGHDVVNQEQINQLKSK----LEQLNTENDNLLSTVAELRSSISSAVDQRGF 1233
            L T   E         +    L+ K    LEQ +T N    +   ++ +  S   D +  
Sbjct: 304  LNTKLMEADKKLKSKTKDFETLEQKYNVLLEQFHTINQEKKAAADQVEALKSQIKDLQSK 363

Query: 1234 EIAELWKQHLAQREADFQKTEHELRVQ-LSAFESKYEQLLDSVQSSTQEETNKIVTMEQV 1292
                       Q E D  K  +E +   +   + KY++L  S  +S +E TN     +++
Sbjct: 364  SANSSSDFKAKQNEIDKLKQINEAQKNFIEDIQRKYDELSQSNLNSPKERTNPF--QQEL 421

Query: 1293 TSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDL 1352
             +L+ +LQD+++  + L ++   + NQI  L+S++++ +                    +
Sbjct: 422  ENLRRRLQDQDKENKALTDQNMALNNQINFLKSQLQNSRQPLPSTQY------------M 469

Query: 1353 RTENQSYKQMQEQSILNINEENAQLK------KSSXXXXXXXXXXXXRVNDAEAKVLELT 1406
              EN S   + E  I N+ E N  +       K              +  D  AK+    
Sbjct: 470  EEENSS--NLDESDIQNMLETNQVISDYENKIKELNETILSLRNAAPKTPDTSAKMKREN 527

Query: 1407 HQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKM 1466
              L+ ++ E+  + ++     TQ   + +++  QL   +K   D     +++L I++L +
Sbjct: 528  SLLKSENEELVSRVNQIKKENTQLKSDIQDLNNQLRNKKK---DFAGSVQNQLNIIKLFL 584

Query: 1467 HENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTAL 1526
            ++    +       EI++ K       KI++       + +L +  E E  KT  ++  +
Sbjct: 585  NKLFADFNY-----EIQKTKQ------KISDEFLTI--LRKLQQQKENETNKTKLLERQI 631

Query: 1527 ENQEIEIVTLNDEITNLQNMVRA-------SSSKIQKHVSFASDTKQGRDEQL--DNTMN 1577
             + + E + L D+I +LQN ++         S +I  H+   S + + RD+Q+  D    
Sbjct: 632  NDLKQENMKLKDKINDLQNNLQKILQENENHSKQISTHIDGLSQSIKERDDQILKDKEKI 691

Query: 1578 KELLDAVPRAELD 1590
            + L + +   E+D
Sbjct: 692  ENLQNKIKGKEID 704


>UniRef50_Q24HK7 Cluster: Viral A-type inclusion protein repeat
            containing protein; n=1; Tetrahymena thermophila
            SB210|Rep: Viral A-type inclusion protein repeat
            containing protein - Tetrahymena thermophila SB210
          Length = 1608

 Score =  208 bits (508), Expect = 1e-51
 Identities = 289/1402 (20%), Positives = 602/1402 (42%), Gaps = 135/1402 (9%)

Query: 212  EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271
            E  K Q+ K   N +  E     E+Q     +E K+++    +   KL+++ + E+    
Sbjct: 200  ETLKVQLEK--SNSLYAEVRKIIEEQEAYIVVEKKELQ-EKQQSQEKLIQSLQQEVKRNE 256

Query: 272  SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTE-LTKKIEL 330
              L Q+  +                 Q+I+ S  +  ++ ++    + N+ + L  K E 
Sbjct: 257  ENLIQKTNELLKTVEDNNEWQERF--QNIKKSVSDSDKLLKEQENIVKNLEQQLLNKSEQ 314

Query: 331  LEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKM-KSPWSQL 389
            +  L  Q  Q ++ L+   A    E++ +   +KK   L S    + T  ++ K    QL
Sbjct: 315  INQLTQQNDQLSEALKKLKAQASNENQNIDHLNKKIEELNSLMQQKETEKEVAKEEKQQL 374

Query: 390  SSETLNQDTDKKINKNEIAKLEMVIQSLNKDL-VDK---EYVISEKDTXXXXXXXXXXGK 445
              +T  Q      NK +IA++++ I++LN +L V K   E  +  K             K
Sbjct: 375  QLKTEEQ------NK-QIAEMQVQIENLNSELKVSKQNYEESMQNKQNSQEIEDKLESEK 427

Query: 446  DTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEI-KDVNVKDLIEK 504
            + L  QL+ ++ + + G     +    E++ + +   +QLK++L  +I K+ ++ D I +
Sbjct: 428  NALKEQLENKYNE-ICGQKDAQISQLQEEIQKYSLEIQQLKEQLQQQINKEASLNDQISQ 486

Query: 505  LKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFS-KVSDSNKEIVRLTEE 563
            L+   E+I  L  ++D       ++ +  + ++  +Q  +   + ++++  K+++    +
Sbjct: 487  LQKESEEIANLKQQLDQVQNKQNEILAQKQQEVTDLQNQLQEMTAQINEGTKKLLDQENK 546

Query: 564  LHHLSQKVAEL---EEEKGNLQLHLVDYDSGRMIESDVYKKMIEME----NLAETRLKAI 616
             H LSQ++ EL   +++   LQ  +V        +      +I+      N    + + I
Sbjct: 547  NHSLSQQIQELVNVQQKNIELQNQIVQLQENEQKQGQEKHSLIQKNEHQVNEINQQKEQI 606

Query: 617  SLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVH--LEEQIDALSAS 674
            + L++++ +L +++  L+   +E ED +  + Q + + + ++  S+   LEE+I+ L   
Sbjct: 607  TKLQAEQRELEEKVQKLKDTIEENEDMINKLKQKEQN-ITNDSSSLKQKLEEEIEELKRH 665

Query: 675  KKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISE 734
              E   V E   +++ ++      +E  K+DI    ++  +E   ++D++ K++ E+   
Sbjct: 666  AHE---VKEQFNVERGEI------IEKHKQDIQKLQESLSKEGQGISDEIAKLNEERTK- 715

Query: 735  LLAKINHEEQSKIQT-QFGIDAKIQERDLYIENIESELSKY---KSRICRLEE----SIA 786
             L+  N E +  I+  Q  I AK +E    ++N+E ++ ++   K    +LEE    S  
Sbjct: 716  -LSDENFELKQNIKDHQKDIQAKEEEIKKIMKNLEEQIQQFNNLKDSYNKLEEESNKSKK 774

Query: 787  VMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEH 846
              E R   L  K  +    L+   K  +    Q+DE + +L           +QL +   
Sbjct: 775  DFEKRMEKLSSKKKEALEKLENNIKELNIQVQQKDEAIQKLETEKTETEKKYQQLKKDSS 834

Query: 847  ENKELQKK-----NQILLEE---NQNLQISLSDMQQHYNALVEKANRTDLAESESTK--Y 896
                +Q++     NQI  E    +Q LQ   ++++Q++ A ++K N   + E ++ K  +
Sbjct: 835  TQSSIQEELNAQINQIKQEYELISQKLQSENNELKQNHEAQIKKLNADQIEEVQNLKDQF 894

Query: 897  QTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKY------ 950
            Q Q   L+ NL +   + Q L  Q K + E+  ++   +    + + ++L  +Y      
Sbjct: 895  QQQTEQLKQNLSQ---QEQELTQQIKIKEEEYNVKLEDEKYITVDNNRILVREYIQQLQC 951

Query: 951  --EKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYI 1008
              E+  + + QLE QLQE K+ I NL   +  L K  +E ++  +    T+  +  E   
Sbjct: 952  ESEQKRDQIKQLEQQLQEKKDQISNLETQIPLL-KQKIEQLECELNSHLTEKQNQQESQ- 1009

Query: 1009 NEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVS 1068
                  N+ L QKDE I  L  +I+  +     ++   E  L   + K   +     ++S
Sbjct: 1010 ------NSSLSQKDEAIKLLQTQISQQEEQLKELIQHKEDNLQSHSEKDSQINSLTSQIS 1063

Query: 1069 KQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNV 1128
             Q+L  ++  ++   L RE+D+  KE KE++     N    E  ++    + +SD    +
Sbjct: 1064 DQVLKLEELQKQKDELQREKDELQKE-KESQQQESQNQLIQEITLLK---QQLSDSQKQI 1119

Query: 1129 DXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAK-LNTELQECYTKIIQLETLNTELTG 1187
            +             K   +   +QE    +E+ AK L  +L     +  + +    + + 
Sbjct: 1120 EENEKQIAQISQEHKTVVDG--LQESYNRKEKEAKQLEDQLIRIQQQHQEEQAELQKKSQ 1177

Query: 1188 HDVVNQEQINQLKSK-LEQLNTENDNLLSTVAELRSSISSAVDQRGFE-----IAELWKQ 1241
             D  N  ++N+   K +E L   N  L++ + +  S++S+ +D    +     I E  K 
Sbjct: 1178 LDSSNMVKLNEKNQKNIEALKRGNRELINMIIDSYSALSNQLDNANIQSQVNAITECIKN 1237

Query: 1242 HLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIV-----TMEQVTSLQ 1296
                   +FQK   E R  +S     Y+  +++V++  ++  NK++     + + +  L 
Sbjct: 1238 TSPDIMKEFQKFLLESRNLIS---EHYQNQINNVKNQEKQRYNKLLEQFNKSQDDIKQLN 1294

Query: 1297 NKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTEN 1356
            +K++  E+  R +QE Y+D+I    + +  I+ ++ AF                D RTE 
Sbjct: 1295 SKIKAAEKLERQVQE-YSDII---ALQKQTIQKKEAAFKDLQIEISSSDA----DKRTE- 1345

Query: 1357 QSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEI 1416
                 +QE+  L + ++N QL   +             + D E    +L  +   + S++
Sbjct: 1346 --LANLQEKVQL-LKQKNEQLISENTAQKELNAKILHDIQDLEQSKAQLEEKAN-QGSDL 1401

Query: 1417 YQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETM 1476
                 E    +    +   +++    +++KR E L  + + EL  +R ++ ++       
Sbjct: 1402 IMLIQEKDSQIQALEESLSSLQTIHEDFQKRNEQLAKKYDFELKKIRTELAQSK------ 1455

Query: 1477 QKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTL 1536
                  E++ L++EL            Q+A+L  A  E+  K N +Q      E E   +
Sbjct: 1456 ------EKIALVDELTA----------QIAQLESAFNEKNQKYNTLQEKYAESEKERALI 1499

Query: 1537 NDEITNLQNMVRASSSKIQKHV 1558
             +E   L N +++ + K +  +
Sbjct: 1500 KNETNQLLNKLKSDAVKSEYQI 1521



 Score =  186 bits (452), Expect = 6e-45
 Identities = 250/1216 (20%), Positives = 538/1216 (44%), Gaps = 97/1216 (7%)

Query: 396  QDTDKKINKNEIAKLEMVIQSLNKDLVDKE-YVISEKDTXXXXXXXXXXGKDTLIAQLQL 454
            Q  D +  K ++ K   +   + K + ++E Y++ EK             ++ LI  LQ 
Sbjct: 195  QKEDYETLKVQLEKSNSLYAEVRKIIEEQEAYIVVEKKELQEKQQS----QEKLIQSLQQ 250

Query: 455  EHQQHMEG--PSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVN-----VKDLIEKLKS 507
            E +++ E        +    ED NE  +  + +K+ ++D  K +      VK+L ++L +
Sbjct: 251  EVKRNEENLIQKTNELLKTVEDNNEWQERFQNIKKSVSDSDKLLKEQENIVKNLEQQLLN 310

Query: 508  AEEQITQL---NDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKV---SDSNKEIVRLT 561
              EQI QL   ND++  A K +    SN    +  + K I+  + +    ++ KE+ +  
Sbjct: 311  KSEQINQLTQQNDQLSEALKKLKAQASNENQNIDHLNKKIEELNSLMQQKETEKEVAK-- 368

Query: 562  EELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIE-MENLAETRLKAISLLE 620
            EE   L  K  E  ++   +Q+ + + +S   +    Y++ ++  +N  E   K    LE
Sbjct: 369  EEKQQLQLKTEEQNKQIAEMQVQIENLNSELKVSKQNYEESMQNKQNSQEIEDK----LE 424

Query: 621  SQKFDLVQELHILQQKYDEV-EDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELA 679
            S+K  L ++L   + KY+E+   K A ISQLQ +     ++   L+EQ+      +  L 
Sbjct: 425  SEKNALKEQL---ENKYNEICGQKDAQISQLQEEIQKYSLEIQQLKEQLQQQINKEASLN 481

Query: 680  LVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKI 739
              I  L+ + E++    + L+  +      L    QE  DL ++L++M+A+ I+E   K+
Sbjct: 482  DQISQLQKESEEIANLKQQLDQVQNKQNEILAQKQQEVTDLQNQLQEMTAQ-INEGTKKL 540

Query: 740  NHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKA 799
              +E         +  +IQE    + N++ +  + +++I +L+E+       ++SL +K 
Sbjct: 541  LDQENKN----HSLSQQIQE----LVNVQQKNIELQNQIVQLQENEQKQGQEKHSLIQKN 592

Query: 800  DQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILL 859
            +   + + ++++  ++   ++ EL  ++  L D     E  + +++ + + +   +  L 
Sbjct: 593  EHQVNEINQQKEQITKLQAEQRELEEKVQKLKDTIEENEDMINKLKQKEQNITNDSSSL- 651

Query: 860  EENQNLQISLSDMQQHYNALVEKAN--RTDLAESESTKYQTQLRDLESNLKRITHEHQTL 917
               Q L+  + ++++H + + E+ N  R ++ E    K++  ++ L+ +L +        
Sbjct: 652  --KQKLEEEIEELKRHAHEVKEQFNVERGEIIE----KHKQDIQKLQESLSKEGQGISDE 705

Query: 918  IVQKKKEIEDLEIEFNTQIESAIRD-KKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNM 976
            I +  +E   L  E N +++  I+D +K +  K E+  + +  LE Q+Q++ N  ++ N 
Sbjct: 706  IAKLNEERTKLSDE-NFELKQNIKDHQKDIQAKEEEIKKIMKNLEEQIQQFNNLKDSYNK 764

Query: 977  NVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQ 1036
              EE NK   +  +K ++K  ++  +  E+  N I +LN  ++QKDE I  L  +    +
Sbjct: 765  LEEESNKSKKDF-EKRMEKLSSKKKEALEKLENNIKELNIQVQQKDEAIQKLETEKTETE 823

Query: 1037 VSYMSMVSDYESKLA---QFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIK 1093
              Y  +  D  ++ +   +   ++  +++E + +S++L   +  N EL+   +  + QIK
Sbjct: 824  KKYQQLKKDSSTQSSIQEELNAQINQIKQEYELISQKL---QSENNELK---QNHEAQIK 877

Query: 1094 ELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQE 1153
            +L   ++    N+            + +S     +             +K+++E+    +
Sbjct: 878  KLNADQIEEVQNLKDQFQQQTEQLKQNLSQQEQEL-TQQIKIKEEEYNVKLEDEKYITVD 936

Query: 1154 --RSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTEND 1211
              R +++E   +L  E ++   +I QLE    E        + QI  LK K+EQL  E +
Sbjct: 937  NNRILVREYIQQLQCESEQKRDQIKQLEQQLQEKKDQISNLETQIPLLKQKIEQLECELN 996

Query: 1212 NLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQL 1271
            + L+     + S +S++ Q+  E  +L +  ++Q+E   ++        L +   K  Q 
Sbjct: 997  SHLTEKQNQQESQNSSLSQKD-EAIKLLQTQISQQEEQLKELIQHKEDNLQSHSEKDSQ- 1054

Query: 1272 LDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRN-----LQEKYADVINQIEILRSE 1326
               + S T + +++++ +E++   +++LQ +++ L+       QE    +I +I +L+ +
Sbjct: 1055 ---INSLTSQISDQVLKLEELQKQKDELQREKDELQKEKESQQQESQNQLIQEITLLKQQ 1111

Query: 1327 IEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSY-------KQMQEQSIL---NINEENAQ 1376
            + D +                    +    +SY       KQ+++Q I       EE A+
Sbjct: 1112 LSDSQKQIEENEKQIAQISQEHKTVVDGLQESYNRKEKEAKQLEDQLIRIQQQHQEEQAE 1171

Query: 1377 LKKSSXXXXXXXXXXXXRVNDAEAKVL-----ELTHQLELKDSEIYQKTHEYTITLTQRN 1431
            L+K S            + N    + L     EL + +    S +  +     I  +Q N
Sbjct: 1172 LQKKSQLDSSNMVKLNEK-NQKNIEALKRGNRELINMIIDSYSALSNQLDNANIQ-SQVN 1229

Query: 1432 DEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKL---- 1487
               E ++    +  K  +    E  + ++        N  + E  +    +E+       
Sbjct: 1230 AITECIKNTSPDIMKEFQKFLLESRNLISEHYQNQINNVKNQEKQRYNKLLEQFNKSQDD 1289

Query: 1488 IEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLN----DEITNL 1543
            I++LN KI  +  L +QV E +  +  +     + + A ++ +IEI + +     E+ NL
Sbjct: 1290 IKQLNSKIKAAEKLERQVQEYSDIIALQKQTIQKKEAAFKDLQIEISSSDADKRTELANL 1349

Query: 1544 QNMVRASSSKIQKHVS 1559
            Q  V+    K ++ +S
Sbjct: 1350 QEKVQLLKQKNEQLIS 1365



 Score =  156 bits (379), Expect = 4e-36
 Identities = 213/1102 (19%), Positives = 476/1102 (43%), Gaps = 65/1102 (5%)

Query: 479  AKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQ-LNDEIDAANKNMIKVKSNHKLKL 537
            ++  +  +++  D+ K+  + D I++LK  E+ +++ L +      K  I    N  LK 
Sbjct: 64   SQTNKNKQEDFKDQQKEKLLLDHIQQLKQIEKSLSEPLQNSTPEDQKKKITSMVNTILK- 122

Query: 538  KQMQKTIDNFSK--VSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQ-LHLVDYDSGRMI 594
            + M K I+   +  V   ++ +V+L +E  +L   + +  ++K  L+ +  VDYD   ++
Sbjct: 123  ENMMKFIEKVKQQIVIKIHERVVKLIDE--NLGDDIPK--DQKDQLKTIFNVDYDEKDLM 178

Query: 595  ESDV---YKKMIEMENLAET--RLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQ 649
            + +    Y  ++++    E    LK      +  +  V+++   Q+ Y  VE K     Q
Sbjct: 179  QQNEEFNYDNILQLFVQKEDYETLKVQLEKSNSLYAEVRKIIEEQEAYIVVEKKELQEKQ 238

Query: 650  LQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNK 709
               +++   ++   ++   + L     EL   +E+   + ++ +  IK   +D + ++ +
Sbjct: 239  QSQEKLIQSLQQ-EVKRNEENLIQKTNELLKTVEDNN-EWQERFQNIKKSVSDSDKLLKE 296

Query: 710  LQNYIQE-NMDLTDKLEKMSA-----EKISELLAKINHEEQSKIQTQFGIDAKIQERDLY 763
             +N ++     L +K E+++      +++SE L K+  +  ++ Q    ++ KI+E +  
Sbjct: 297  QENIVKNLEQQLLNKSEQINQLTQQNDQLSEALKKLKAQASNENQNIDHLNKKIEELNSL 356

Query: 764  IENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDEL 823
            ++  E+E    K    +L+        +   ++ + + L S L+  ++ Y E ++Q  + 
Sbjct: 357  MQQKETEKEVAKEEKQQLQLKTEEQNKQIAEMQVQIENLNSELKVSKQNYEE-SMQNKQN 415

Query: 824  VNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQI--LLEENQNLQISLSDMQQHYNALVE 881
               +   ++ ++   K+ LE ++     QK  QI  L EE Q   + +  +++     + 
Sbjct: 416  SQEIEDKLESEKNALKEQLENKYNEICGQKDAQISQLQEEIQKYSLEIQQLKEQLQQQIN 475

Query: 882  KANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIR 941
            K    +   S+  K   ++ +L+  L ++ ++   ++ QK++E+ DL+ +          
Sbjct: 476  KEASLNDQISQLQKESEEIANLKQQLDQVQNKQNEILAQKQQEVTDLQNQLQEMTAQINE 535

Query: 942  DKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKH--VQKQQTQ 999
              K L ++  KN     Q++  +   + NIE  N  V+       +  +KH  +QK + Q
Sbjct: 536  GTKKLLDQENKNHSLSQQIQELVNVQQKNIELQNQIVQLQENEQKQGQEKHSLIQKNEHQ 595

Query: 1000 SPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKL-E 1058
              +  +Q   +I KL A  ++ +E++  L   I   +   ++ +   E  +   ++ L +
Sbjct: 596  VNEINQQK-EQITKLQAEQRELEEKVQKLKDTIEENE-DMINKLKQKEQNITNDSSSLKQ 653

Query: 1059 NMEEEMQRVSKQLLDSK-QHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISST 1117
             +EEE++ + +   + K Q N E   ++ +    I++L+E+           EG  IS  
Sbjct: 654  KLEEEIEELKRHAHEVKEQFNVERGEIIEKHKQDIQKLQESL--------SKEGQGISDE 705

Query: 1118 IEPMSDDANNV-DXXXXXXXXXXXXLK-VQEEEEFIQE-RSVLQEQSAKLNTELQECYTK 1174
            I  ++++   + D             K +Q +EE I++    L+EQ  + N  L++ Y K
Sbjct: 706  IAKLNEERTKLSDENFELKQNIKDHQKDIQAKEEEIKKIMKNLEEQIQQFN-NLKDSYNK 764

Query: 1175 IIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFE 1234
            +   E  N      +   ++  ++ K  LE+L      L   V +   +I     ++   
Sbjct: 765  L--EEESNKSKKDFEKRMEKLSSKKKEALEKLENNIKELNIQVQQKDEAIQKLETEK--T 820

Query: 1235 IAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTS 1294
              E   Q L +  +     + EL  Q++  + +YE +   +QS   E     +       
Sbjct: 821  ETEKKYQQLKKDSSTQSSIQEELNAQINQIKQEYELISQKLQSENNE-----LKQNHEAQ 875

Query: 1295 LQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRT 1354
            ++    D+ E ++NL++++     Q++   S+ E E                    +++ 
Sbjct: 876  IKKLNADQIEEVQNLKDQFQQQTEQLKQNLSQQEQE--------LTQQIKIKEEEYNVKL 927

Query: 1355 ENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDS 1414
            E++ Y  +    IL + E   QL+  S            ++ + + ++  L  Q+ L   
Sbjct: 928  EDEKYITVDNNRIL-VREYIQQLQCESEQKRDQIKQLEQQLQEKKDQISNLETQIPLLKQ 986

Query: 1415 EIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDL-TYEKESELAILRLKMHENANHY 1473
            +I Q   E    LT++ ++ E+    L + ++ I+ L T   + E  +  L  H+  N  
Sbjct: 987  KIEQLECELNSHLTEKQNQQESQNSSLSQKDEAIKLLQTQISQQEEQLKELIQHKEDNLQ 1046

Query: 1474 ETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEI-E 1532
               +K+S+I    L  +++ ++ +   L KQ  EL +  +E   +    Q   +NQ I E
Sbjct: 1047 SHSEKDSQIN--SLTSQISDQVLKLEELQKQKDELQREKDELQKEKESQQQESQNQLIQE 1104

Query: 1533 IVTLNDEITNLQNMVRASSSKI 1554
            I  L  ++++ Q  +  +  +I
Sbjct: 1105 ITLLKQQLSDSQKQIEENEKQI 1126



 Score =  151 bits (365), Expect = 2e-34
 Identities = 266/1248 (21%), Positives = 537/1248 (43%), Gaps = 151/1248 (12%)

Query: 143  DVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXX 202
            ++ HL+  I+E ++ +   + + ++ +     LQ K  E+++ I A+ +           
Sbjct: 342  NIDHLNKKIEELNSLMQQKETEKEVAKEEKQQLQLKTEEQNKQI-AEMQVQIENLNSELK 400

Query: 203  XXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDI-ESKDVRISSLEEANKLLE 261
                        KQ   ++++   + +   K++ +    +I   KD +IS L+E     E
Sbjct: 401  VSKQNYEESMQNKQNSQEIEDKLESEKNALKEQLENKYNEICGQKDAQISQLQE-----E 455

Query: 262  AARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSC--EEKTEIEEKGSLEIA 319
              ++  SLE  +L ++L+Q              L K+S E +   ++  +++ K +  +A
Sbjct: 456  IQKY--SLEIQQLKEQLQQQINKEASLNDQISQLQKESEEIANLKQQLDQVQNKQNEILA 513

Query: 320  N-MTELTKKIELLEHLNCQIRQTNKEL---ENKLATMGTESKAVSSPSKKG----SPLIS 371
                E+T     L+ +  QI +  K+L   ENK  ++  + + + +  +K     + ++ 
Sbjct: 514  QKQQEVTDLQNQLQEMTAQINEGTKKLLDQENKNHSLSQQIQELVNVQQKNIELQNQIVQ 573

Query: 372  RKSGRNTASKMKSPWSQLSSETLNQDTDKK--INK--NEIAKLEMVIQSLNKDLVDKEYV 427
             +       + K    Q +   +N+   +K  I K   E  +LE  +Q L   + + E +
Sbjct: 574  LQENEQKQGQEKHSLIQKNEHQVNEINQQKEQITKLQAEQRELEEKVQKLKDTIEENEDM 633

Query: 428  ISE-KDTXXXXXXXXXXGKDTLIAQLQ--LEHQQHMEGPSLIHVGTNTED-VNEIAKVQE 483
            I++ K             K  L  +++    H   ++    +  G   E    +I K+QE
Sbjct: 634  INKLKQKEQNITNDSSSLKQKLEEEIEELKRHAHEVKEQFNVERGEIIEKHKQDIQKLQE 693

Query: 484  QLKQE---LNDEIKDVNVK--DLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLK 538
             L +E   ++DEI  +N +   L ++    ++ I     +I A  + + K+  N + +++
Sbjct: 694  SLSKEGQGISDEIAKLNEERTKLSDENFELKQNIKDHQKDIQAKEEEIKKIMKNLEEQIQ 753

Query: 539  QMQKTIDNFSKVSD-SNKEIVRLTEELHHLSQKVAE-LEEEKGNL-QLHLVDYDSGRMIE 595
            Q     D+++K+ + SNK      + +  LS K  E LE+ + N+ +L++        I+
Sbjct: 754  QFNNLKDSYNKLEEESNKSKKDFEKRMEKLSSKKKEALEKLENNIKELNIQVQQKDEAIQ 813

Query: 596  ------SDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKL----- 644
                  ++  KK  +++  + T+      L +Q   + QE  ++ QK     ++L     
Sbjct: 814  KLETEKTETEKKYQQLKKDSSTQSSIQEELNAQINQIKQEYELISQKLQSENNELKQNHE 873

Query: 645  ADISQLQSDQVCSEIKSV--HLEEQIDAL----SASKKELALVIE------NLKLDKEQL 692
            A I +L +DQ+  E++++    ++Q + L    S  ++EL   I+      N+KL+ E+ 
Sbjct: 874  AQIKKLNADQI-EEVQNLKDQFQQQTEQLKQNLSQQEQELTQQIKIKEEEYNVKLEDEK- 931

Query: 693  YGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEK---ISELLAKINHEEQSKIQT 749
            Y T+ +      + + +LQ   ++  D   +LE+   EK   IS L  +I   +Q   Q 
Sbjct: 932  YITVDNNRILVREYIQQLQCESEQKRDQIKQLEQQLQEKKDQISNLETQIPLLKQKIEQL 991

Query: 750  QFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSL-ERKADQLGSYLQE 808
            +  +++ + E+    E+  S LS+    I  L+  I+  E++   L + K D L S+  E
Sbjct: 992  ECELNSHLTEKQNQQESQNSSLSQKDEAIKLLQTQISQQEEQLKELIQHKEDNLQSH-SE 1050

Query: 809  KQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQIS 868
            K    +  T Q  + V +L  L       +KQ  E++ E  ELQK+ +            
Sbjct: 1051 KDSQINSLTSQISDQVLKLEEL-------QKQKDELQREKDELQKEKE------------ 1091

Query: 869  LSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDL 928
             S  Q+  N L+++     L + + +  Q Q+ + E  + +I+ EH+T++   ++     
Sbjct: 1092 -SQQQESQNQLIQEIT---LLKQQLSDSQKQIEENEKQIAQISQEHKTVVDGLQESYNRK 1147

Query: 929  EIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLEL 988
            E E     +  IR ++   E+ +  ++  +QL++     K N +N   N+E L + N EL
Sbjct: 1148 EKEAKQLEDQLIRIQQQHQEE-QAELQKKSQLDSS-NMVKLNEKN-QKNIEALKRGNREL 1204

Query: 989  IDKHVQKQQTQSPDYTEQYI-NEINKLNALLKQKDEEIIALNQKI-----NNAQVSYMSM 1042
            I+  +      S       I +++N +   +K    +I+   QK      N     Y + 
Sbjct: 1205 INMIIDSYSALSNQLDNANIQSQVNAITECIKNTSPDIMKEFQKFLLESRNLISEHYQNQ 1264

Query: 1043 VSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTF 1102
            +++ +++  Q   KL     + Q   KQL    +  E+L+  V+E  D I   K+T    
Sbjct: 1265 INNVKNQEKQRYNKLLEQFNKSQDDIKQLNSKIKAAEKLERQVQEYSDIIALQKQT---- 1320

Query: 1103 EMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSA 1162
               I K E       IE  S DA+                 +QE+ + +++++   EQ  
Sbjct: 1321 ---IQKKEAAFKDLQIEISSSDADK----------RTELANLQEKVQLLKQKN---EQLI 1364

Query: 1163 KLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRS 1222
              NT  +E   KI+           HD+   + + Q K++LE+   +  +L+  + E  S
Sbjct: 1365 SENTAQKELNAKIL-----------HDI---QDLEQSKAQLEEKANQGSDLIMLIQEKDS 1410

Query: 1223 SISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEE 1282
             I +  +     ++ L   H      DFQK   +L         KY+  L  +++   + 
Sbjct: 1411 QIQALEES----LSSLQTIH-----EDFQKRNEQLA-------KKYDFELKKIRTELAQS 1454

Query: 1283 TNKIVTMEQVTS----LQNKLQDKEEHLRNLQEKYADVINQIEILRSE 1326
              KI  ++++T+    L++   +K +    LQEKYA+   +  ++++E
Sbjct: 1455 KEKIALVDELTAQIAQLESAFNEKNQKYNTLQEKYAESEKERALIKNE 1502



 Score =  102 bits (244), Expect = 9e-20
 Identities = 200/1091 (18%), Positives = 465/1091 (42%), Gaps = 80/1091 (7%)

Query: 54   FERAQKCLENAALVSKRIKEHRKATAELLGRPFVPGISESLANTLKQKEILMEKIKQYKE 113
            +E + +  +N+  +  +++  + A  E L   +     +  A   + +E + +   + ++
Sbjct: 406  YEESMQNKQNSQEIEDKLESEKNALKEQLENKYNEICGQKDAQISQLQEEIQKYSLEIQQ 465

Query: 114  LSKRSSTTIVRXXXXXXXXXXXXXXXQ-LGDVTHLSNTIKEKDNA-LSVLQVKMKIMETT 171
            L ++    I +               + + ++    + ++ K N  L+  Q ++  ++  
Sbjct: 466  LKEQLQQQINKEASLNDQISQLQKESEEIANLKQQLDQVQNKQNEILAQKQQEVTDLQNQ 525

Query: 172  ILDLQEKINE-KDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEA 230
            + ++  +INE   ++++ +NK  +                  + + Q+ ++QEN    E 
Sbjct: 526  LQEMTAQINEGTKKLLDQENKNHSLSQQIQELVNVQQKNI--ELQNQIVQLQEN----EQ 579

Query: 231  EWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXX 290
            +   EK  L++  E +   I+  +E    L+A + E+  +  KL   +E+          
Sbjct: 580  KQGQEKHSLIQKNEHQVNEINQQKEQITKLQAEQRELEEKVQKLKDTIEENEDMINKLKQ 639

Query: 291  XXXXLAKQS--IEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENK 348
                +   S  ++   EE+ E  ++ + E+     + +  E++E    + +Q  ++L+  
Sbjct: 640  KEQNITNDSSSLKQKLEEEIEELKRHAHEVKEQFNVERG-EIIE----KHKQDIQKLQES 694

Query: 349  LATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKN--- 405
            L+    E + +S    K +   ++ S  N   K      Q   +   ++  KKI KN   
Sbjct: 695  LSK---EGQGISDEIAKLNEERTKLSDENFELKQNIKDHQKDIQAKEEEI-KKIMKNLEE 750

Query: 406  EIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTL------IAQLQLEHQQH 459
            +I +   +  S NK  +++E   S+KD            K+ L      I +L ++ QQ 
Sbjct: 751  QIQQFNNLKDSYNK--LEEESNKSKKDFEKRMEKLSSKKKEALEKLENNIKELNIQVQQK 808

Query: 460  MEGPSLIHVG-TNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDE 518
             E    +    T TE   +  K     +  + +E+ +  +  + ++ +   +++   N+E
Sbjct: 809  DEAIQKLETEKTETEKKYQQLKKDSSTQSSIQEEL-NAQINQIKQEYELISQKLQSENNE 867

Query: 519  IDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEK 578
            +   ++  IK K N   +++++Q   D F + ++  K+   L+++   L+Q++ +++EE+
Sbjct: 868  LKQNHEAQIK-KLNAD-QIEEVQNLKDQFQQQTEQLKQ--NLSQQEQELTQQI-KIKEEE 922

Query: 579  GNLQLHLVDY---DSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELH---- 631
             N++L    Y   D+ R++  +  +++         ++K +     +K D +  L     
Sbjct: 923  YNVKLEDEKYITVDNNRILVREYIQQLQCESEQKRDQIKQLEQQLQEKKDQISNLETQIP 982

Query: 632  ILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQ 691
            +L+QK +++E +L   S L   Q   E ++  L ++ +A+   + +++   E LK   + 
Sbjct: 983  LLKQKIEQLECELN--SHLTEKQNQQESQNSSLSQKDEAIKLLQTQISQQEEQLKELIQH 1040

Query: 692  LYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAE--KISELLAKINHEEQSKIQT 749
                ++   ++K+  +N L + I + +   ++L+K   E  +  + L K    +Q + Q 
Sbjct: 1041 KEDNLQS-HSEKDSQINSLTSQISDQVLKLEELQKQKDELQREKDELQKEKESQQQESQN 1099

Query: 750  QFGIDAKIQERDLYIENIESELSKYKSRICRL-EESIAVMEDRRYSLERKADQLGSYLQE 808
            Q   +  + ++ L   + + ++ + + +I ++ +E   V++  + S  RK  +      +
Sbjct: 1100 QLIQEITLLKQQL--SDSQKQIEENEKQIAQISQEHKTVVDGLQESYNRKEKEAKQLEDQ 1157

Query: 809  KQKAYSEYTIQEDELVNRLAVLMDHDRVV---EKQLLEIEHENKELQKKNQILLEENQNL 865
              +   ++  ++ EL  +    +D   +V   EK    IE   +  ++   ++++    L
Sbjct: 1158 LIRIQQQHQEEQAELQKKSQ--LDSSNMVKLNEKNQKNIEALKRGNRELINMIIDSYSAL 1215

Query: 866  --QISLSDMQQHYNALVEKANRT--DLAESESTKYQTQLRDLESNLKRITHEHQTLIVQK 921
              Q+  +++Q   NA+ E    T  D+ + E  K+  + R+L S  +   ++   +  Q+
Sbjct: 1216 SNQLDNANIQSQVNAITECIKNTSPDIMK-EFQKFLLESRNLIS--EHYQNQINNVKNQE 1272

Query: 922  KKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEEL 981
            K+    L  +FN   +    D K LN K    I+   +LE Q+QEY + I    +  + +
Sbjct: 1273 KQRYNKLLEQFNKSQD----DIKQLNSK----IKAAEKLERQVQEYSDIIA---LQKQTI 1321

Query: 982  NKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMS 1041
             K      D  ++   + +   TE  +  + +   LLKQK+E++I+ N          + 
Sbjct: 1322 QKKEAAFKDLQIEISSSDADKRTE--LANLQEKVQLLKQKNEQLISENTAQKELNAKILH 1379

Query: 1042 MVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQIL--VREQDDQIKELKETK 1099
             + D E   AQ   K     + +  + ++    +   E L  L  + E   +  E    K
Sbjct: 1380 DIQDLEQSKAQLEEKANQGSDLIMLIQEKDSQIQALEESLSSLQTIHEDFQKRNEQLAKK 1439

Query: 1100 LTFEMNIPKTE 1110
              FE+   +TE
Sbjct: 1440 YDFELKKIRTE 1450



 Score = 89.0 bits (211), Expect = 9e-16
 Identities = 147/759 (19%), Positives = 322/759 (42%), Gaps = 80/759 (10%)

Query: 858  LLEENQNLQISLSDMQQHYNALVEK--------------ANRTDLAESESTKYQTQLRDL 903
            LLE+ +NL     D+ Q   + +++              AN T   +  S + Q Q +  
Sbjct: 5    LLEKGKNLTNKAKDLVQQIGSEIDQQNQAQLKGLTGQSPANSTPQNQQRSQQQQQQQQQS 64

Query: 904  ESNLKR----ITHEHQTLIVQKKKEIEDLEIEFNTQIE-SAIRDKK---------VLNEK 949
            ++N  +       + + L++   ++++ +E   +  ++ S   D+K         +L E 
Sbjct: 65   QTNKNKQEDFKDQQKEKLLLDHIQQLKQIEKSLSEPLQNSTPEDQKKKITSMVNTILKEN 124

Query: 950  YEKNIEYVTQ---LEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQ 1006
              K IE V Q   ++   +  K   ENL  ++ +  K  L+ I  +V   +       E+
Sbjct: 125  MMKFIEKVKQQIVIKIHERVVKLIDENLGDDIPKDQKDQLKTI-FNVDYDEKDLMQQNEE 183

Query: 1007 YINEINKLNALLKQKDEEIIALN-QKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQ 1065
            + N  N L   ++++D E + +  +K N+       ++ + E+ +     +L+  ++  +
Sbjct: 184  F-NYDNILQLFVQKEDYETLKVQLEKSNSLYAEVRKIIEEQEAYIVVEKKELQEKQQSQE 242

Query: 1066 RVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFE--MNIPKTEGMIISSTIEPMSD 1123
            ++ + L    + NEE   L+++ ++ +K +++     E   NI K+    +S + + + +
Sbjct: 243  KLIQSLQQEVKRNEE--NLIQKTNELLKTVEDNNEWQERFQNIKKS----VSDSDKLLKE 296

Query: 1124 DANNVDXXXXXXXXXXXXLK--VQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETL 1181
              N V             +    Q+ ++  +    L+ Q++  N  +     KI +L +L
Sbjct: 297  QENIVKNLEQQLLNKSEQINQLTQQNDQLSEALKKLKAQASNENQNIDHLNKKIEELNSL 356

Query: 1182 NTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQ 1241
              +      V +E+  QL+ K E+ N +   +   +  L S +   V ++ +E +   KQ
Sbjct: 357  MQQKETEKEVAKEEKQQLQLKTEEQNKQIAEMQVQIENLNSELK--VSKQNYEESMQNKQ 414

Query: 1242 HLAQREADFQKTEHELRVQLSAFESKYEQLL---DSVQSSTQEETNKI-----VTMEQVT 1293
            +  + E   +  ++ L+ QL   E+KY ++    D+  S  QEE  K         EQ+ 
Sbjct: 415  NSQEIEDKLESEKNALKEQL---ENKYNEICGQKDAQISQLQEEIQKYSLEIQQLKEQLQ 471

Query: 1294 SLQNK----------LQDKEEHLRNLQEKYADVIN-QIEILRSEIEDEKVAFXXXXXXXX 1342
               NK          LQ + E + NL+++   V N Q EIL  + ++             
Sbjct: 472  QQINKEASLNDQISQLQKESEEIANLKQQLDQVQNKQNEILAQKQQEVTDLQNQLQEMTA 531

Query: 1343 XXXXXXXXDLRTENQSYKQMQE-QSILNINEENAQLKKS----SXXXXXXXXXXXXRVND 1397
                     L  EN+++   Q+ Q ++N+ ++N +L+                    +  
Sbjct: 532  QINEGTKKLLDQENKNHSLSQQIQELVNVQQKNIELQNQIVQLQENEQKQGQEKHSLIQK 591

Query: 1398 AEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKES 1457
             E +V E+  Q E + +++  +  E    + +  D  E     + + +++ +++T +  S
Sbjct: 592  NEHQVNEINQQKE-QITKLQAEQRELEEKVQKLKDTIEENEDMINKLKQKEQNITNDSSS 650

Query: 1458 ELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVA 1517
                L  ++ E   H   ++++  +ER ++IE+    I +   L + +++  + + +E+A
Sbjct: 651  LKQKLEEEIEELKRHAHEVKEQFNVERGEIIEKHKQDIQK---LQESLSKEGQGISDEIA 707

Query: 1518 KTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQK 1556
            K NE +T L ++  E   L   I + Q  ++A   +I+K
Sbjct: 708  KLNEERTKLSDENFE---LKQNIKDHQKDIQAKEEEIKK 743


>UniRef50_A2DD37 Cluster: Viral A-type inclusion protein, putative;
            n=1; Trichomonas vaginalis G3|Rep: Viral A-type inclusion
            protein, putative - Trichomonas vaginalis G3
          Length = 1553

 Score =  206 bits (502), Expect = 5e-51
 Identities = 309/1431 (21%), Positives = 609/1431 (42%), Gaps = 120/1431 (8%)

Query: 216  QQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLA 275
            + + K   N  A   E +D+   L  + +  +  I   +   K L+A R +++ + ++L 
Sbjct: 117  ESLKKENANLKARIKELEDQLALLNTERDGYNSIIKDKDNQFKALQAERDDLAAKINQLT 176

Query: 276  QELEQXXXXXXXXXXXXXXLAKQSIEPSCEE----KTEIEEKGSLEIANMTELTKKIELL 331
            Q+  Q               ++ S+  S  +    K ++++K S      T+L++  + +
Sbjct: 177  QKC-QLNDAEKNALQAKLDSSENSLNESRNQCNFIKQQLDDKTSQCNDLGTKLSQADQTI 235

Query: 332  EHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSS 391
                  I Q N E++NK   +      ++  SK+ S  + +K    T  K+K     L +
Sbjct: 236  AEKIEAINQLNNEIDNKSKIIKQYEDELAK-SKEDSEELMKKYQEET-DKLKKDSENLQN 293

Query: 392  ETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQ 451
            E  NQ +  ++N ++   L+  ++ L  D  + E  I                 +  + +
Sbjct: 294  ELQNQKSLAELNASDKGNLQSAVKQLQDDNSNLEKQIKVLQDDKSNLEIQREKLEQEVEE 353

Query: 452  LQLEHQQH-----MEGPSLIH-VGTNTEDVNEIAKVQEQLKQELNDEIKDVN--VKDLIE 503
            L+   Q++      E   L   V     +++ + K  E L     +EI ++N  ++DL  
Sbjct: 354  LKKSQQENDEKYQKEKEDLTQTVNNQNNEISNLKKQNEDLSNSTTNEINNLNKQIQDLQN 413

Query: 504  KLKSAEEQITQLNDEIDAANKNMIKVKS-NHKLKLKQ--MQKTIDNFSK-VSDSNKEIVR 559
            +    E+Q    N+ +   N  +  +K  N +L+ ++  +QK  +N S  V+D N EI  
Sbjct: 414  QKSDLEKQNADYNNTVSNNNDELANLKKLNQELQNEKSNLQKETENLSNTVNDKNNEIEE 473

Query: 560  LTEELHHLSQKVAELEEEKGNLQLHLVDYDSG----RMIESDVYKKMIEMENLAETRLKA 615
            L ++   L  +   L++ K +L   +   D      +    D+  +  ++E   E     
Sbjct: 474  LKKQNEDLQNEKQNLQKVKEDLTNTITTKDDEIKDLKKQNEDLQNQNNDLEKQKEDLNNT 533

Query: 616  ISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASK 675
            ++  +S+  +L  +   LQ+   +  D   DI+ L+      E K   LE +ID ++A  
Sbjct: 534  VANKDSELNNLKNDNQQLQEANKKQND---DINNLKKSNQDLEDKVTDLEGKIDEMTAEN 590

Query: 676  KELALVIENLKLDKEQLYG----TIKDLENDKEDIMNKLQNYIQENMDLT---DKLEKMS 728
            + L   ++   L  + L G    T+ +L  +   +  ++ +   +  DL    D LEK  
Sbjct: 591  EGLMENVKTRDLQLDNLQGEHSQTVDELNQNNLSLQMQIDSLNSDVNDLKSQKDSLEKDK 650

Query: 729  AE---KISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESI 785
            ++   K+ EL   +  E+ S +      + + Q+    ++ I +EL+K         ++I
Sbjct: 651  SDLEKKVKELEEALEDEKNSSLLNSSNFNEESQK---LMDKI-NELTKQNRE---KNQNI 703

Query: 786  AVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIE 845
              +E+ + +L++  D L   L   +K Y +    + ELV +   L++      +   E+ 
Sbjct: 704  KKLENEKANLQQNNDNLNQRLDNVKKQYEDLQASKSELVGKYNDLVEKFNKERQTNNELS 763

Query: 846  HENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKAN--RTDLAESESTKYQTQLRDL 903
             +N+  +++ Q L+ +  +L+   SD+ Q YN LV K N  R + A+++S   Q Q++ L
Sbjct: 764  QQNQAQKQQIQQLMNDLASLRDGKSDIVQKYNDLVAKFNDERQEAAKTKS-DLQNQIQQL 822

Query: 904  ESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQ 963
            +  L +   E      Q K +I + ++E         +DK   ++  E+ +  +     Q
Sbjct: 823  KDALAKA--ESNQKETQNKLDISNSDLEKE-------KDK---SKSLEEELAALKSKLQQ 870

Query: 964  LQEYKNNIENLNMNVEELN-KMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKD 1022
            +QE K N+E+   N  + N   N EL DK + K Q ++ D     +N+IN+L   LKQK+
Sbjct: 871  VQEEKANLESDLENERQNNSSSNAELSDK-LSKLQQENRD----LVNQINQLQNDLKQKE 925

Query: 1023 EEIIALN---QKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNE 1079
             EI  ++     +NN      S ++D + K  + + KL N+ ++ +R  K L+D    N 
Sbjct: 926  SEIQKVSSDLDNLNNVIQDLESQMNDMQGKNDELSKKLSNLVDDNERKDK-LIDDL--NS 982

Query: 1080 ELQILVREQDDQIKELKETKLTFEMNIPKTEGM--IISSTIEPMSD--DANNVDXXXXXX 1135
            +L  L  E+D    +L ET+        + E +  +I      +S+  D NN        
Sbjct: 983  QLSNLNNEKDSLTNKLSETESEKLDLANQNEKLLKVIEDLQRSLSEEKDKNNSSLLSLGD 1042

Query: 1136 XXXXXXL---KVQEEEEFI----QERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGH 1188
                  L   KV + E+ +    QE     E+ +KLN +L+E    I +++    +L   
Sbjct: 1043 FGKENALLKEKVADLEKQVSNLKQENETQNEEISKLNNDLREAADYIEKIKQQYLKLKKE 1102

Query: 1189 DVVNQEQINQLK-------SKLEQLNTENDNLLSTVAEL------RSSISSAVDQRGFE- 1234
            +   +E+I++LK       S ++QLN +  +L   + EL        S S ++++   E 
Sbjct: 1103 NQALKEEISKLKAENDEHNSTIDQLNDDKRDLEEQLKELNITLDEEKSKSFSLNENASEE 1162

Query: 1235 ------IAELWKQHL---AQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNK 1285
                  I +  K  L    Q+  + +   H LR Q+  ++S  ++L   + S+ QEE + 
Sbjct: 1163 LKNKDDINDGLKSQLKSQVQQNKEIEAENHNLRSQVDQYKSSNDELETQI-SNYQEENSN 1221

Query: 1286 IVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXX 1345
            +   + ++S +NK +D  E  + L++K    + Q+E    E E++               
Sbjct: 1222 L--QDLLSSSENKNKDINEQNKQLKQK----LQQLENSLRESENKYNNLVKSNCDEITKL 1275

Query: 1346 XXXXXDLRTENQSYKQMQEQSILNINE--ENAQLKKSSXXXXXXXXXXXXRVND-AEAKV 1402
                 D   +N  Y   ++  I  + E   N  ++KS             R N   ++++
Sbjct: 1276 SQQLQDAMQDNAKYSSEKDNLIKKLKELNNNLNVQKSQNKQIENQRSFLERENQRLKSQI 1335

Query: 1403 LELT-HQLELKDSE-IYQKTHEYTIT---LTQRNDEFENVRQQLVEYEKRIEDLTYEKES 1457
             EL+ +Q+   D E +  +    TI    L + NDE     + L     ++     + E 
Sbjct: 1336 SELSKNQIPSVDIEDLKYQMRTLTIENEHLKKNNDEIRQRMRHLESTNAQLSIQNNQNEL 1395

Query: 1458 ELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVA 1517
            +L  L  +    +  ++ ++KE+  +    I+ +N K       N  ++E +K+ EE   
Sbjct: 1396 KLCTLEQRCVWLSGAHDKLRKEN-FDLSSTIDTMNSKSQYETKPNVYISEGSKSQEEYEI 1454

Query: 1518 KTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGR 1568
            K  E+   +E    E+   N+   ++  M + +    + + S A +  + R
Sbjct: 1455 KIRELILQIERLHKELEDKNENNNDVIRMKQTNQQLSKVNQSLALENSRLR 1505



 Score =  165 bits (401), Expect = 9e-39
 Identities = 252/1293 (19%), Positives = 562/1293 (43%), Gaps = 105/1293 (8%)

Query: 309  EIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSK-KGS 367
            E+E+   +  +   E  K+ E L+  N  ++   KELE++LA + TE    +S  K K +
Sbjct: 97   ELEKTYGISASKFGEWMKQFESLKKENANLKARIKELEDQLALLNTERDGYNSIIKDKDN 156

Query: 368  PLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYV 427
               + ++ R+    + +  +QL+ +    D +K   +   AKL+    SLN+      ++
Sbjct: 157  QFKALQAERD---DLAAKINQLTQKCQLNDAEKNALQ---AKLDSSENSLNESRNQCNFI 210

Query: 428  ---ISEKDTXXXXXXXXXXGKDTLIAQ-LQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQE 483
               + +K +            D  IA+ ++  +Q + E  +   +    ED  E+AK +E
Sbjct: 211  KQQLDDKTSQCNDLGTKLSQADQTIAEKIEAINQLNNEIDNKSKIIKQYED--ELAKSKE 268

Query: 484  QLKQELNDEIKDVNVKDLIEKLKSAEEQI-TQLNDEIDAANKNMIKVKSNHKLKLKQMQK 542
               +EL  + ++       +KLK   E +  +L ++   A  N    K N +  +KQ+Q 
Sbjct: 269  D-SEELMKKYQEET-----DKLKKDSENLQNELQNQKSLAELN-ASDKGNLQSAVKQLQD 321

Query: 543  TIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKM 602
              DN    S+  K+I  L ++  +L  +  +LE+E   L+    + D     E +   + 
Sbjct: 322  --DN----SNLEKQIKVLQDDKSNLEIQREKLEQEVEELKKSQQENDEKYQKEKEDLTQT 375

Query: 603  IEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSV 662
            +  +N   + LK  +  E        E++ L ++  +++++ +D+ +  +D   +   + 
Sbjct: 376  VNNQNNEISNLKKQN--EDLSNSTTNEINNLNKQIQDLQNQKSDLEKQNADYNNTVSNN- 432

Query: 663  HLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTD 722
               +++  L    +EL     NL+ + E L  T+ D  N+ E++        ++N DL +
Sbjct: 433  --NDELANLKKLNQELQNEKSNLQKETENLSNTVNDKNNEIEELK-------KQNEDLQN 483

Query: 723  KLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLE 782
              EK + +K+ E L      +  +I+     D K Q  DL  +N  ++L K K       
Sbjct: 484  --EKQNLQKVKEDLTNTITTKDDEIK-----DLKKQNEDL--QNQNNDLEKQK------- 527

Query: 783  ESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLL 842
                  ED   ++  K  +L +   + Q+       Q D++ N    L   ++ +E ++ 
Sbjct: 528  ------EDLNNTVANKDSELNNLKNDNQQLQEANKKQNDDINN----LKKSNQDLEDKVT 577

Query: 843  EIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLA-ESESTKYQTQLR 901
            ++E +  E+  +N+ L+E  +   + L ++Q  ++  V++ N+ +L+ + +     + + 
Sbjct: 578  DLEGKIDEMTAENEGLMENVKTRDLQLDNLQGEHSQTVDELNQNNLSLQMQIDSLNSDVN 637

Query: 902  DLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLE 961
            DL+S    +  +   L    +K++++LE     +  S++ +    NE+ +K ++ + +L 
Sbjct: 638  DLKSQKDSLEKDKSDL----EKKVKELEEALEDEKNSSLLNSSNFNEESQKLMDKINELT 693

Query: 962  AQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQK 1021
             Q +E   NI+ L      L + N + +++ +   + Q  D        + K N L+++ 
Sbjct: 694  KQNREKNQNIKKLENEKANLQQNN-DNLNQRLDNVKKQYEDLQASKSELVGKYNDLVEKF 752

Query: 1022 DEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEEL 1081
            ++E    N +++    +    +    + LA       ++ ++   +  +  D +Q   + 
Sbjct: 753  NKE-RQTNNELSQQNQAQKQQIQQLMNDLASLRDGKSDIVQKYNDLVAKFNDERQEAAKT 811

Query: 1082 QILVREQDDQIKELKETKLTFEMNIPKTEGM--IISSTIEPMSDDANNVDXXXXXXXXXX 1139
            +    +  +QI++LK+     E N  +T+    I +S +E   D + +++          
Sbjct: 812  K---SDLQNQIQQLKDALAKAESNQKETQNKLDISNSDLEKEKDKSKSLEEELAALKSKL 868

Query: 1140 XXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQL 1199
               +VQEE+  ++  S L+ +    ++   E   K+ +L+  N +L       Q  + Q 
Sbjct: 869  Q--QVQEEKANLE--SDLENERQNNSSSNAELSDKLSKLQQENRDLVNQINQLQNDLKQK 924

Query: 1200 KSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRV 1259
            +S++++++++ DNL + + +L S ++  +  +  E+++     +   E    K   +L  
Sbjct: 925  ESEIQKVSSDLDNLNNVIQDLESQMND-MQGKNDELSKKLSNLVDDNERK-DKLIDDLNS 982

Query: 1260 QLSAFESKYEQLLDSVQSSTQEETNKIVTMEQ----VTSLQNKLQDKEEHLRNLQEKYAD 1315
            QLS   ++ + L + +  +  E+ +     E+    +  LQ  L ++++   +      D
Sbjct: 983  QLSNLNNEKDSLTNKLSETESEKLDLANQNEKLLKVIEDLQRSLSEEKDKNNSSLLSLGD 1042

Query: 1316 VINQIEILRSEIED-EKVA--FXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINE 1372
               +  +L+ ++ D EK                     DLR E   Y +  +Q  L + +
Sbjct: 1043 FGKENALLKEKVADLEKQVSNLKQENETQNEEISKLNNDLR-EAADYIEKIKQQYLKLKK 1101

Query: 1373 ENAQLKKSSXXXXXXXXXXXXRVN-------DAEAKVLELTHQLELKDSEIYQKTHEYTI 1425
            EN  LK+               ++       D E ++ EL   L+ + S+ +      + 
Sbjct: 1102 ENQALKEEISKLKAENDEHNSTIDQLNDDKRDLEEQLKELNITLDEEKSKSFSLNENASE 1161

Query: 1426 TLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERV 1485
             L  ++D  + ++ QL    ++ +++  E E+     ++  ++++N     Q  +  E  
Sbjct: 1162 ELKNKDDINDGLKSQLKSQVQQNKEI--EAENHNLRSQVDQYKSSNDELETQISNYQEEN 1219

Query: 1486 KLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLN-DEITNLQ 1544
              +++L   ++ S + NK + E NK L++++ +        EN+   +V  N DEIT L 
Sbjct: 1220 SNLQDL---LSSSENKNKDINEQNKQLKQKLQQLENSLRESENKYNNLVKSNCDEITKLS 1276

Query: 1545 NMVRASSSKIQKHVSFASDTKQGRDEQLDNTMN 1577
              ++ +     K+ S   D    + ++L+N +N
Sbjct: 1277 QQLQDAMQDNAKY-SSEKDNLIKKLKELNNNLN 1308



 Score =  153 bits (371), Expect = 4e-35
 Identities = 282/1420 (19%), Positives = 590/1420 (41%), Gaps = 134/1420 (9%)

Query: 147  LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXX 206
            +   + +K +  + L  K+   + TI +  E IN+ +  I+ K+K               
Sbjct: 210  IKQQLDDKTSQCNDLGTKLSQADQTIAEKIEAINQLNNEIDNKSKIIKQYEDELAKSKED 269

Query: 207  XXXXXEDTKQQMTKMQENFIAMEAEWKDEKQ----------RLLKDIESKDVRISSLEEA 256
                 +  +++  K++++   ++ E +++K            L   ++      S+LE+ 
Sbjct: 270  SEELMKKYQEETDKLKKDSENLQNELQNQKSLAELNASDKGNLQSAVKQLQDDNSNLEKQ 329

Query: 257  NKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIE--EKG 314
             K+L+  +  + ++  KL QE+E+                +   +    +  EI   +K 
Sbjct: 330  IKVLQDDKSNLEIQREKLEQEVEELKKSQQENDEKYQKEKEDLTQTVNNQNNEISNLKKQ 389

Query: 315  SLEIANMT-----ELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPL 369
            + +++N T      L K+I+ L++    + + N +  N   T+   +  +++  K    L
Sbjct: 390  NEDLSNSTTNEINNLNKQIQDLQNQKSDLEKQNADYNN---TVSNNNDELANLKKLNQEL 446

Query: 370  ISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVIS 429
                  +N  S ++     LS+   +++ + +  K +   L+   Q+L K   D    I+
Sbjct: 447  ------QNEKSNLQKETENLSNTVNDKNNEIEELKKQNEDLQNEKQNLQKVKEDLTNTIT 500

Query: 430  EKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQEL 489
             KD            +D       LE Q+     +   V     ++N +    +QL QE 
Sbjct: 501  TKD--DEIKDLKKQNEDLQNQNNDLEKQKEDLNNT---VANKDSELNNLKNDNQQL-QEA 554

Query: 490  NDEIKDVNVKDLIEKLKSAEEQITQLN---DEIDAANKNMIKVKSNHKLKLKQMQKTIDN 546
            N +  D ++ +L +  +  E+++T L    DE+ A N+ +++      L+L  +Q   ++
Sbjct: 555  NKKQND-DINNLKKSNQDLEDKVTDLEGKIDEMTAENEGLMENVKTRDLQLDNLQG--EH 611

Query: 547  FSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEME 606
               V + N+  + L  ++  L+  V +L+ +K +L+            +SD+ KK+ E+E
Sbjct: 612  SQTVDELNQNNLSLQMQIDSLNSDVNDLKSQKDSLEKD----------KSDLEKKVKELE 661

Query: 607  NLAETRLKAISLLESQKFDLVQELHILQQKYDEV----EDKLADISQLQSDQVCSEIKSV 662
               E   K  SLL S  F+  +E   L  K +E+     +K  +I +L++++   +  + 
Sbjct: 662  EALEDE-KNSSLLNSSNFN--EESQKLMDKINELTKQNREKNQNIKKLENEKANLQQNND 718

Query: 663  HLEEQID-------ALSASKKELALVIENL--KLDKEQLYGTIKDLENDKEDIMNKLQNY 713
            +L +++D        L ASK EL     +L  K +KE+   T  +L    +    ++Q  
Sbjct: 719  NLNQRLDNVKKQYEDLQASKSELVGKYNDLVEKFNKER--QTNNELSQQNQAQKQQIQQL 776

Query: 714  IQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSK 773
            + +   L D    +  +K ++L+AK N E Q   +T+  +  +IQ+    +   ES   +
Sbjct: 777  MNDLASLRDGKSDI-VQKYNDLVAKFNDERQEAAKTKSDLQNQIQQLKDALAKAESNQKE 835

Query: 774  YKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDH 833
             ++++      +   +D+  SLE +   L S LQ+ Q+   E    E +L N        
Sbjct: 836  TQNKLDISNSDLEKEKDKSKSLEEELAALKSKLQQVQE---EKANLESDLENERQNNSSS 892

Query: 834  DRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESES 893
            +  +  +L +++ EN++L   NQI   +N +L+   S++Q+  + L    N     ES+ 
Sbjct: 893  NAELSDKLSKLQQENRDL--VNQINQLQN-DLKQKESEIQKVSSDLDNLNNVIQDLESQM 949

Query: 894  TKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKN 953
               Q +  +L   L  +  +++    +K K I+DL    N+Q+ +   +K  L  K  + 
Sbjct: 950  NDMQGKNDELSKKLSNLVDDNE----RKDKLIDDL----NSQLSNLNNEKDSLTNKLSET 1001

Query: 954  IEYVTQLEAQLQEYKNNIENLNMNV-EELNKMNLELID-KHVQKQQTQSPDYTEQYINEI 1011
                  L  Q ++    IE+L  ++ EE +K N  L+      K+     +       ++
Sbjct: 1002 ESEKLDLANQNEKLLKVIEDLQRSLSEEKDKNNSSLLSLGDFGKENALLKEKVADLEKQV 1061

Query: 1012 NKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEM-QRVSKQ 1070
            + L    + ++EEI  LN  +  A        +DY  K+ Q   KL+   + + + +SK 
Sbjct: 1062 SNLKQENETQNEEISKLNNDLREA--------ADYIEKIKQQYLKLKKENQALKEEISKL 1113

Query: 1071 LLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDX 1130
              ++ +HN  +  L  ++ D  ++LKE  +T +    K+      S  E  S++  N D 
Sbjct: 1114 KAENDEHNSTIDQLNDDKRDLEEQLKELNITLDEEKSKS-----FSLNENASEELKNKDD 1168

Query: 1131 XXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDV 1190
                        +VQ+ +E   E   L+ Q  +  +   E  T+I   +  N+ L     
Sbjct: 1169 INDGLKSQLKS-QVQQNKEIEAENHNLRSQVDQYKSSNDELETQISNYQEENSNL----- 1222

Query: 1191 VNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREAD- 1249
              Q+ ++  ++K + +N +N  L   + +L +S+  + ++           +L +   D 
Sbjct: 1223 --QDLLSSSENKNKDINEQNKQLKQKLQQLENSLRESENK---------YNNLVKSNCDE 1271

Query: 1250 FQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKI-VTMEQVTSLQNKLQDKEEHLRN 1308
              K   +L+  +    +KY    D++    +E  N + V   Q   ++N+    E   + 
Sbjct: 1272 ITKLSQQLQDAMQD-NAKYSSEKDNLIKKLKELNNNLNVQKSQNKQIENQRSFLERENQR 1330

Query: 1309 LQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSIL 1368
            L+ + ++ +++ +I   +IED K                   ++R   +  +    Q  L
Sbjct: 1331 LKSQISE-LSKNQIPSVDIEDLKYQM-RTLTIENEHLKKNNDEIRQRMRHLESTNAQ--L 1386

Query: 1369 NINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLT 1428
            +I     +LK  +                 E   L  T       S+   K + Y    +
Sbjct: 1387 SIQNNQNELKLCTLEQRCVWLSGAHDKLRKENFDLSSTIDTMNSKSQYETKPNVYISEGS 1446

Query: 1429 QRNDEFE-NVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKL 1487
            +  +E+E  +R+ +++ E+  ++L  + E+   ++R+K        +T Q+ S++ +   
Sbjct: 1447 KSQEEYEIKIRELILQIERLHKELEDKNENNNDVIRMK--------QTNQQLSKVNQSLA 1498

Query: 1488 IEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALE 1527
            +E   ++       NK     ++  +  VA  NE Q   E
Sbjct: 1499 LENSRLRFWLECEKNKS----HRLSDSYVAVKNENQRLFE 1534



 Score =  144 bits (350), Expect = 1e-32
 Identities = 231/1105 (20%), Positives = 472/1105 (42%), Gaps = 90/1105 (8%)

Query: 143  DVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXX 202
            +  +LSNT+ +K+N +  L+ + + ++    +LQ+   +    I  K+            
Sbjct: 456  ETENLSNTVNDKNNEIEELKKQNEDLQNEKQNLQKVKEDLTNTITTKDD-EIKDLKKQNE 514

Query: 203  XXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEA 262
                     E  K+ +     N  +     K++ Q+L +  + ++  I++L+++N+ LE 
Sbjct: 515  DLQNQNNDLEKQKEDLNNTVANKDSELNNLKNDNQQLQEANKKQNDDINNLKKSNQDLED 574

Query: 263  ARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLA---KQSIEPSCEEKTEIEEKGSLEIA 319
               ++  +  ++  E E               L     Q+++   +    ++ +     +
Sbjct: 575  KVTDLEGKIDEMTAENEGLMENVKTRDLQLDNLQGEHSQTVDELNQNNLSLQMQIDSLNS 634

Query: 320  NMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTA 379
            ++ +L  + + LE     + +  KELE  L              +K S L++  +    +
Sbjct: 635  DVNDLKSQKDSLEKDKSDLEKKVKELEEAL------------EDEKNSSLLNSSNFNEES 682

Query: 380  SKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNK--DLVDKEYVISEKDTXXXX 437
             K+    ++L+ +   ++ + K  +NE A L+    +LN+  D V K+Y    +D     
Sbjct: 683  QKLMDKINELTKQNREKNQNIKKLENEKANLQQNNDNLNQRLDNVKKQY----EDLQASK 738

Query: 438  XXXXXXGKDTLIAQLQLEHQQHME--GPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKD 495
                    D L+ +   E Q + E    +        + +N++A +++  K ++  +  D
Sbjct: 739  SELVGKYND-LVEKFNKERQTNNELSQQNQAQKQQIQQLMNDLASLRDG-KSDIVQKYND 796

Query: 496  VNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNK 555
            +  K   E+ ++A+ + + L ++I      + K +SN K    ++  +  +  K  D +K
Sbjct: 797  LVAKFNDERQEAAKTK-SDLQNQIQQLKDALAKAESNQKETQNKLDISNSDLEKEKDKSK 855

Query: 556  EIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKA 615
                L EEL  L  K+ +++EEK NL+    D ++ R   S    ++ +           
Sbjct: 856  S---LEEELAALKSKLQQVQEEKANLE---SDLENERQNNSSSNAELSD----------K 899

Query: 616  ISLLESQKFDLVQELHILQ----QKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDAL 671
            +S L+ +  DLV +++ LQ    QK  E++   +D+  L  + V  +++S   + Q    
Sbjct: 900  LSKLQQENRDLVNQINQLQNDLKQKESEIQKVSSDLDNL--NNVIQDLESQMNDMQGKND 957

Query: 672  SASKKELALVIENLKLDK--EQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSA 729
              SKK   LV +N + DK  + L   + +L N+K+ + NKL     E +DL ++ EK+  
Sbjct: 958  ELSKKLSNLVDDNERKDKLIDDLNSQLSNLNNEKDSLTNKLSETESEKLDLANQNEKL-L 1016

Query: 730  EKISELLAKINHEEQSKIQTQFGIDAKIQERDLY---IENIESELSKYKSRICRLEESIA 786
            + I +L   ++ E+     +   +    +E  L    + ++E ++S  K       E I+
Sbjct: 1017 KVIEDLQRSLSEEKDKNNSSLLSLGDFGKENALLKEKVADLEKQVSNLKQENETQNEEIS 1076

Query: 787  VMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEH 846
             + +    L   AD +    Q+  K   E    ++E+    A   +H+  ++ QL + + 
Sbjct: 1077 KLNN---DLREAADYIEKIKQQYLKLKKENQALKEEISKLKAENDEHNSTID-QLNDDKR 1132

Query: 847  ENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESN 906
            + +E  K+  I L+E ++   SL++     NA  E  N+ D+ +   ++ ++Q++     
Sbjct: 1133 DLEEQLKELNITLDEEKSKSFSLNE-----NASEELKNKDDINDGLKSQLKSQVQQ-NKE 1186

Query: 907  LKRITHEHQTLIVQKKKEIEDLEIEFNTQIE--SAIRDKKVLNEKYEKNI-EYVTQLEAQ 963
            ++   H  ++ + Q K   ++LE + +   E  S ++D    +E   K+I E   QL+ +
Sbjct: 1187 IEAENHNLRSQVDQYKSSNDELETQISNYQEENSNLQDLLSSSENKNKDINEQNKQLKQK 1246

Query: 964  LQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPD---YTEQYINEINKL----NA 1016
            LQ+ +N++         L K N + I K  Q+ Q    D   Y+ +  N I KL    N 
Sbjct: 1247 LQQLENSLRESENKYNNLVKSNCDEITKLSQQLQDAMQDNAKYSSEKDNLIKKLKELNNN 1306

Query: 1017 LLKQKDEEIIALNQK--INNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDS 1074
            L  QK +     NQ+  +        S +S+  SK    +  +E+++ +M+ ++ +    
Sbjct: 1307 LNVQKSQNKQIENQRSFLERENQRLKSQISEL-SKNQIPSVDIEDLKYQMRTLTIENEHL 1365

Query: 1075 KQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXX 1134
            K++N+E++  +R  +    +L       E+ +   E   +  +         N D     
Sbjct: 1366 KKNNDEIRQRMRHLESTNAQLSIQNNQNELKLCTLEQRCVWLSGAHDKLRKENFDLSSTI 1425

Query: 1135 XXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTEL-----TGHD 1189
                       +   +I E S  QE+      EL      I+Q+E L+ EL       +D
Sbjct: 1426 DTMNSKSQYETKPNVYISEGSKSQEEYEIKIREL------ILQIERLHKELEDKNENNND 1479

Query: 1190 VVNQEQINQLKSKLEQ-LNTENDNL 1213
            V+  +Q NQ  SK+ Q L  EN  L
Sbjct: 1480 VIRMKQTNQQLSKVNQSLALENSRL 1504



 Score =  130 bits (315), Expect = 2e-28
 Identities = 197/956 (20%), Positives = 403/956 (42%), Gaps = 115/956 (12%)

Query: 699  LENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDA-KI 757
            LEN   ++ N+ + + ++N  LTD+   M  +K+ EL            +  +GI A K 
Sbjct: 63   LENKNTNLSNESKMFARQNKALTDE-NNMLKKKLGEL------------EKTYGISASKF 109

Query: 758  QERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYT 817
             E     E+++ E +  K+RI  LE+ +A++   R       D   S +++K   +    
Sbjct: 110  GEWMKQFESLKKENANLKARIKELEDQLALLNTER-------DGYNSIIKDKDNQFKALQ 162

Query: 818  IQEDELVNRLAVLMDHDRV--VEKQLLEIE---HENKELQKKNQILLEENQ--------- 863
             + D+L  ++  L    ++   EK  L+ +    EN   + +NQ    + Q         
Sbjct: 163  AERDDLAAKINQLTQKCQLNDAEKNALQAKLDSSENSLNESRNQCNFIKQQLDDKTSQCN 222

Query: 864  NLQISLSDMQQHYNALVEKANRTDLAESESTK----YQTQLRDLESNLKRITHEHQTLIV 919
            +L   LS   Q     +E  N+ +      +K    Y+ +L   + + + +  ++Q    
Sbjct: 223  DLGTKLSQADQTIAEKIEAINQLNNEIDNKSKIIKQYEDELAKSKEDSEELMKKYQEETD 282

Query: 920  QKKKEIEDLEIEFNTQ---IESAIRDKKVLNEKYEKNIEYVTQLEAQ---LQEYKNNI-- 971
            + KK+ E+L+ E   Q    E    DK  L    ++  +  + LE Q   LQ+ K+N+  
Sbjct: 283  KLKKDSENLQNELQNQKSLAELNASDKGNLQSAVKQLQDDNSNLEKQIKVLQDDKSNLEI 342

Query: 972  --ENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALN 1029
              E L   VEEL K   E    + +K Q +  D T+   N+ N+++ L KQ ++   +  
Sbjct: 343  QREKLEQEVEELKKSQQE----NDEKYQKEKEDLTQTVNNQNNEISNLKKQNEDLSNSTT 398

Query: 1030 QKIN--NAQV-SYMSMVSDYESKLAQFTTKLENMEEEMQRVSK--QLLDSKQHN-----E 1079
             +IN  N Q+    +  SD E + A +   + N  +E+  + K  Q L +++ N     E
Sbjct: 399  NEINNLNKQIQDLQNQKSDLEKQNADYNNTVSNNNDELANLKKLNQELQNEKSNLQKETE 458

Query: 1080 ELQILVREQDDQIKELK---ETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXX 1136
             L   V +++++I+ELK   E     + N+ K +   +++TI    D+  ++        
Sbjct: 459  NLSNTVNDKNNEIEELKKQNEDLQNEKQNLQKVK-EDLTNTITTKDDEIKDLKKQNEDLQ 517

Query: 1137 XXXXXLKVQEEE-------------EFIQERSVLQEQSAKLNTEL-------QECYTKII 1176
                 L+ Q+E+                 +   LQE + K N ++       Q+   K+ 
Sbjct: 518  NQNNDLEKQKEDLNNTVANKDSELNNLKNDNQQLQEANKKQNDDINNLKKSNQDLEDKVT 577

Query: 1177 QLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIA 1236
             LE    E+T  +    E +     +L+ L  E+   +  + +   S+   +D    ++ 
Sbjct: 578  DLEGKIDEMTAENEGLMENVKTRDLQLDNLQGEHSQTVDELNQNNLSLQMQIDSLNSDVN 637

Query: 1237 EL--WKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTS 1294
            +L   K  L + ++D +K   EL   L   + K   LL+S  S+  EE+ K+  M+++  
Sbjct: 638  DLKSQKDSLEKDKSDLEKKVKELEEALE--DEKNSSLLNS--SNFNEESQKL--MDKINE 691

Query: 1295 LQNKLQDKEEHLRNLQEKYA------DVINQ-IEILRSEIEDEKVAFXXXXXXXXXXXXX 1347
            L  + ++K ++++ L+ + A      D +NQ ++ ++ + ED + +              
Sbjct: 692  LTKQNREKNQNIKKLENEKANLQQNNDNLNQRLDNVKKQYEDLQASKSELVGKYNDLVEK 751

Query: 1348 XXXDLRTENQ--SYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLEL 1405
               + +T N+     Q Q+Q I  +  + A L+               + ND   +  + 
Sbjct: 752  FNKERQTNNELSQQNQAQKQQIQQLMNDLASLRDGKSDIVQKYNDLVAKFNDERQEAAKT 811

Query: 1406 THQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLK 1465
               L+ +  ++     +      +  ++ + +    +E EK   D +   E ELA L+ K
Sbjct: 812  KSDLQNQIQQLKDALAKAESNQKETQNKLD-ISNSDLEKEK---DKSKSLEEELAALKSK 867

Query: 1466 MHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTA 1525
            + +       ++ + E ER           + +  L+ ++++L +   + V + N++Q  
Sbjct: 868  LQQVQEEKANLESDLENERQN-------NSSSNAELSDKLSKLQQENRDLVNQINQLQND 920

Query: 1526 LENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELL 1581
            L+ +E EI  ++ ++ NL N+++   S++        +  +     +D+   K+ L
Sbjct: 921  LKQKESEIQKVSSDLDNLNNVIQDLESQMNDMQGKNDELSKKLSNLVDDNERKDKL 976



 Score =  111 bits (267), Expect = 2e-22
 Identities = 165/834 (19%), Positives = 357/834 (42%), Gaps = 83/834 (9%)

Query: 771  LSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVL 830
            +S    ++  L++ +  +     +L  +  +L S + E +K  +       EL +    L
Sbjct: 1    MSASDPKVQELQQKVNKLTTANETLNNENLKLKSQVVEYEKGNTPMVAVRKELDD----L 56

Query: 831  MDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEK----ANRT 886
             +    +E +   + +E+K   ++N+ L +EN  L+  L ++++ Y     K      + 
Sbjct: 57   KNKYSFLENKNTNLSNESKMFARQNKALTDENNMLKKKLGELEKTYGISASKFGEWMKQF 116

Query: 887  DLAESESTKYQTQLRDLESNLKRITHE---HQTLIVQKKKEIEDLEIEFNTQIESAIRDK 943
            +  + E+   + ++++LE  L  +  E   + ++I  K  + + L+ E    + + I   
Sbjct: 117  ESLKKENANLKARIKELEDQLALLNTERDGYNSIIKDKDNQFKALQAE-RDDLAAKINQ- 174

Query: 944  KVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDY 1003
              L +K + N      L+A+L   +N   +LN +  + N +  +L DK      +Q  D 
Sbjct: 175  --LTQKCQLNDAEKNALQAKLDSSEN---SLNESRNQCNFIKQQLDDK-----TSQCNDL 224

Query: 1004 TEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEE 1063
                  ++++ +  + +K E I  LN +I+N       ++  YE +LA+     E+ EE 
Sbjct: 225  G----TKLSQADQTIAEKIEAINQLNNEIDNKS----KIIKQYEDELAK---SKEDSEEL 273

Query: 1064 MQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSD 1123
            M          K++ EE   L ++ ++   EL+  K   E+N   ++   + S ++ + D
Sbjct: 274  M----------KKYQEETDKLKKDSENLQNELQNQKSLAELN--ASDKGNLQSAVKQLQD 321

Query: 1124 DANNVDXXXXXXXXXXXXLKVQEE--EEFIQERSVLQEQSAKLNTELQECYTKIIQLETL 1181
            D +N++            L++Q E  E+ ++E    Q+++ +   + +E  T+ +  +  
Sbjct: 322  DNSNLEKQIKVLQDDKSNLEIQREKLEQEVEELKKSQQENDEKYQKEKEDLTQTVNNQ-- 379

Query: 1182 NTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAEL---RSSISSAVDQRGFEIAEL 1238
            N E++     N++  N   +++  LN +  +L +  ++L    +  ++ V     E+A L
Sbjct: 380  NNEISNLKKQNEDLSNSTTNEINNLNKQIQDLQNQKSDLEKQNADYNNTVSNNNDELANL 439

Query: 1239 WK--QHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQ 1296
             K  Q L   +++ QK    L   ++   ++ E+L    +    E+ N     E +T   
Sbjct: 440  KKLNQELQNEKSNLQKETENLSNTVNDKNNEIEELKKQNEDLQNEKQNLQKVKEDLT--- 496

Query: 1297 NKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTEN 1356
            N +  K++ +++L+++  D+ NQ   L  + ED                     +L+ +N
Sbjct: 497  NTITTKDDEIKDLKKQNEDLQNQNNDLEKQKED--------LNNTVANKDSELNNLKNDN 548

Query: 1357 QSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEI 1416
            Q   Q+QE +    N++   LKKS+            ++++  A+   L   ++ +D ++
Sbjct: 549  Q---QLQEAN-KKQNDDINNLKKSNQDLEDKVTDLEGKIDEMTAENEGLMENVKTRDLQL 604

Query: 1417 YQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKES---ELAILRLKMHENANHY 1473
                 E++ T+ + N    +++ Q+      + DL  +K+S   + + L  K+ E     
Sbjct: 605  DNLQGEHSQTVDELNQNNLSLQMQIDSLNSDVNDLKSQKDSLEKDKSDLEKKVKELEEAL 664

Query: 1474 ETMQKESEIERVKLIEE---LNVKITESVSLNKQVAELNKALEEEVA----KTNEMQTAL 1526
            E  +  S +      EE   L  KI E    N++  +  K LE E A      + +   L
Sbjct: 665  EDEKNSSLLNSSNFNEESQKLMDKINELTKQNREKNQNIKKLENEKANLQQNNDNLNQRL 724

Query: 1527 EN---QEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMN 1577
            +N   Q  ++     E+    N +    +K ++  +  S   Q + +Q+   MN
Sbjct: 725  DNVKKQYEDLQASKSELVGKYNDLVEKFNKERQTNNELSQQNQAQKQQIQQLMN 778



 Score = 61.3 bits (142), Expect = 2e-07
 Identities = 106/592 (17%), Positives = 238/592 (40%), Gaps = 38/592 (6%)

Query: 141  LGDVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXX 200
            +  +  L N +K+K++ +  +   +  +   I DL+ ++N+    ++ KN   +      
Sbjct: 911  VNQINQLQNDLKQKESEIQKVSSDLDNLNNVIQDLESQMND----MQGKNDELSKKLSNL 966

Query: 201  XXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSL-EEANKL 259
                       +D   Q++ +           KD     L + ES+ + +++  E+  K+
Sbjct: 967  VDDNERKDKLIDDLNSQLSNLNNE--------KDSLTNKLSETESEKLDLANQNEKLLKV 1018

Query: 260  LEAARFEISLEHSK---LAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSL 316
            +E  +  +S E  K       L                L KQ      E +T+ EE   L
Sbjct: 1019 IEDLQRSLSEEKDKNNSSLLSLGDFGKENALLKEKVADLEKQVSNLKQENETQNEEISKL 1078

Query: 317  EIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGR 376
               ++ E    IE ++    ++++ N+ L+ +++ +  E+   +S   + +        +
Sbjct: 1079 N-NDLREAADYIEKIKQQYLKLKKENQALKEEISKLKAENDEHNSTIDQLNDDKRDLEEQ 1137

Query: 377  NTASKMKSPWSQLSSETLNQDTDKKI-NKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXX 435
                 +     +  S +LN++  +++ NK++I   + +   L   +   + + +E     
Sbjct: 1138 LKELNITLDEEKSKSFSLNENASEELKNKDDIN--DGLKSQLKSQVQQNKEIEAENHNLR 1195

Query: 436  XXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTN-TEDVNEIAKVQEQLKQELNDEIK 494
                      D L  Q+    +++     L+    N  +D+NE  K  +Q  Q+L + ++
Sbjct: 1196 SQVDQYKSSNDELETQISNYQEENSNLQDLLSSSENKNKDINEQNKQLKQKLQQLENSLR 1255

Query: 495  DVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSN 554
            +   K     +KS  ++IT+L+ ++  A ++  K  S     +K++++  +N +     N
Sbjct: 1256 ESENK-YNNLVKSNCDEITKLSQQLQDAMQDNAKYSSEKDNLIKKLKELNNNLNVQKSQN 1314

Query: 555  KEIVR----LTEELHHLSQKVAELEEEK-GNLQLHLVDYDSGRM-IESDVYKKMIE---- 604
            K+I      L  E   L  +++EL + +  ++ +  + Y    + IE++  KK  +    
Sbjct: 1315 KQIENQRSFLERENQRLKSQISELSKNQIPSVDIEDLKYQMRTLTIENEHLKKNNDEIRQ 1374

Query: 605  -MENLAETRLKAISLLESQK----FDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEI 659
             M +L  T  + +S+  +Q       L Q    L   +D++  +  D+S           
Sbjct: 1375 RMRHLESTNAQ-LSIQNNQNELKLCTLEQRCVWLSGAHDKLRKENFDLSSTIDTMNSKSQ 1433

Query: 660  KSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQ 711
                    I   S S++E  + I  L L  E+L+  ++D   +  D++   Q
Sbjct: 1434 YETKPNVYISEGSKSQEEYEIKIRELILQIERLHKELEDKNENNNDVIRMKQ 1485


>UniRef50_A2F531 Cluster: Viral A-type inclusion protein, putative;
            n=1; Trichomonas vaginalis G3|Rep: Viral A-type inclusion
            protein, putative - Trichomonas vaginalis G3
          Length = 3748

 Score =  205 bits (501), Expect = 7e-51
 Identities = 298/1502 (19%), Positives = 650/1502 (43%), Gaps = 129/1502 (8%)

Query: 152  KEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKA--TTXXXXXXXXXXXXXXX 209
            K K     V   K KI E  I  LQE  +E+ QI + K++   TT               
Sbjct: 309  KLKKQIAKVESEKTKI-EDEIKHLQE--DEEPQIKKLKDRLDETTTKTQIAEKKLGEMRK 365

Query: 210  XXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISL 269
              ED++Q++ + ++N I    E  ++ +    +++S + +I  ++     L     ++  
Sbjct: 366  TIEDSRQKLAQRRQNLIERRKELTNDAENTNTELQSINNQIQEIDSEFNKLNGLVNKVQS 425

Query: 270  EHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIE 329
            +HSK    L++              LA++  + +  ++ + EEK S E A + ++  +++
Sbjct: 426  DHSKKKSALQEQ-------------LAQKQKDLNDLKRKQAEEKASRE-AEIAKINDQLQ 471

Query: 330  -LLEHLNCQIRQTNKELENKLATMGTESKAVSSP-SKKGSPLISRKSGR-----NTASKM 382
              ++  N   +  N +L+N++     + K + S  +KK   L  + + R         ++
Sbjct: 472  KTMKEYNDLNQPQNVDLKNEIDQATKDLKELESRVNKKREELFGKNNQRVAELNKLNEQL 531

Query: 383  KSPWSQL---SSETLNQDTDKKINKNEI-AKLEMVIQSLNK--------------DLVDK 424
            KS   ++     E  +   + +  KNE+ A++E V   ++K              DL D+
Sbjct: 532  KSKMDEMVKADQELQSAKDEHEAKKNELKAEIESVSDEISKLKDELEVIPDFEVDDLKDQ 591

Query: 425  -EYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDV---NEIAK 480
               ++ EK+             ++ I  L+ E Q+       I    N  D    +E +K
Sbjct: 592  LNELLKEKEELEKEKIKNNDELNSSIIMLKDEIQKEKANKDKISEEKNKRDKELNDEKSK 651

Query: 481  VQEQLKQELNDEIKDVN------VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHK 534
            +Q++L     DEI++ N      V+DL  K+  A+     + D+ID   +   KV+  +K
Sbjct: 652  LQDELDSLQLDEIENENDQLFEEVEDLKSKVDDAKILYNDMVDKIDDLKQQRSKVEQKYK 711

Query: 535  LKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLV-DYDSGRM 593
               KQ ++  D   KVS    E+    + L+       EL ++   +   +V        
Sbjct: 712  DLEKQNKEKSDEIEKVSKEISELKEKLDNLNQFKDNTPELHQKVDAMNEQIVKKSQENEK 771

Query: 594  IESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSD 653
            I+ ++ K   E+++L E  ++ I ++  ++  + +++  ++Q+ +E +    +I  + + 
Sbjct: 772  IQEEMNKLNEELQHL-ENEMEEIEVVNDERETIQEKIDNIKQQIEEKKKSNEEIQDIMNL 830

Query: 654  QVCSEIKSVHLEEQIDALSASKKELALVIENLK---LDKEQLYGTIKDLENDKEDIMNKL 710
             + +E  +    + I+ + A  +E+   I+ L+    D+++L   + +  N  +  +  L
Sbjct: 831  LIEAENDAQKELDDIEIVEAQSEEIRQRIQTLQDNLQDRKKLNNELTEQNNKLQKELKDL 890

Query: 711  QNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLY------I 764
            QN + +   + D  E ++ +K+ E+  +IN  +          +  I+E + +      I
Sbjct: 891  QNELDQTELVNDDSESLN-KKLDEIKEQINERKSQNENNTEQNEKLIEEIEKFAKELDEI 949

Query: 765  ENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQ-EKQKA--------YSE 815
            E IE +  K +++I  L++ I   +      ++  + L   LQ  KQK          S+
Sbjct: 950  EIIEDKSDKLQAQISELQKQIDEKQKNNEQTDKSNNDLEHELQITKQKLDSMSSVKNNSD 1009

Query: 816  YTIQEDELVNR-LAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQ 874
            Y   E E VN+ +  + D +  +++   E++ +NKEL++   I  + ++ L+  +  + +
Sbjct: 1010 YLKSEIENVNKEIEKIRDTNNKLKQ---ELQDKNKELEEMTDI-ADNSEELKEKIDSVNE 1065

Query: 875  HYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITH-EHQTLIVQKKKEIEDLEIEFN 933
                 V  AN T + E     ++  L++ E+ L+ I H +  T  +QK  +    +I   
Sbjct: 1066 EITKRV--ANNTTIDELIRHLHE-DLKNAEAKLQSIPHVDDNTDSLQKSLDEVLAQISQK 1122

Query: 934  TQIESAIRDK--KVLNEKYEKNIEY--VTQLEAQLQEYKNNIENLNMNVEELNKMNLELI 989
             +    + D+  +++ EK EK  E   +  +  + +E  + IE +   +EE  K N ++ 
Sbjct: 1123 QRENDELNDEISRLIQEKEEKTDELNNMETIPDKREEISSEIETVKSQIEEKKKNNEKIA 1182

Query: 990  DKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESK 1049
            +++  K+  +  +   Q ++++   +  L+   +EI    Q+I+  Q     +  + E  
Sbjct: 1183 EEN--KKLAEELENLRQTLSKMETSDQPLENIQKEIETTKQEISEKQKELDELKQELEQI 1240

Query: 1050 LAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKE-LKETKLTFEMNIPK 1108
              +  +K + + EE++ +  Q+ +  + NEE+     E+  ++ E LKE +   ++   K
Sbjct: 1241 KDEDQSKADEISEEIENIKTQIDEKNKKNEEIAKNNEEKQSELDEKLKELQ---DLEEIK 1297

Query: 1109 TEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXL-KVQEEEEFIQERSVLQEQSAKLNTE 1167
             E   I+  IE    +                 L K++++ E I+    +++   KL  E
Sbjct: 1298 DETEEINQQIEETQKEIETKKQQKENNNKLNEELDKLKQDLEQIEN---VEDNVEKLTEE 1354

Query: 1168 LQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQL---NTENDNLLSTVAELRSSI 1224
            +++  + I     LN ++   + V +E++N LK +LE++     ++D +   + +++  I
Sbjct: 1355 IEKVKSDIDSKHQLNNDIKEANEVVEEELNSLKEELEKIEPVEDKSDEIRKEIVKIQKEI 1414

Query: 1225 SS--AVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEE 1282
             +  A +    E  EL  + L   +   ++   E +      +++ E L  S++   +  
Sbjct: 1415 ETKKATNCGISESNELLNKELNDLKNQLEEIAEE-KDDSEEIKAEIENLHKSIEEKKEHN 1473

Query: 1283 TNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXX 1342
             N     E +    +KLQ++ + +  +++K  ++ ++IE L+S+IE++            
Sbjct: 1474 ANTQQNNENMKEELSKLQEEFDQIEVVEDKAEEIHSEIEKLKSQIEEKN----TTNNDIK 1529

Query: 1343 XXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKV 1402
                    +L    + Y ++  +   + +EE +Q                  +      +
Sbjct: 1530 EANDILNEELNNLQKQYDEIDVEE--DKSEELSQKVTDLQKLLEEKKSQNETIKSGNENI 1587

Query: 1403 LELTHQL--ELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELA 1460
            L+    L  EL + E+   + E      +   + E ++Q + + +K+ E+ T  K +E  
Sbjct: 1588 LKELQSLQNELDNIEVVSSSSE------EGEKKIEKLKQMISDKQKQNEETT--KHNEEL 1639

Query: 1461 ILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTN 1520
              ++K  EN  +     K+   +  + IEE+  KIT+    N++ ++LN AL+EE    +
Sbjct: 1640 DNQIKDLENELNEIIPVKDKSNDLQQQIEEIKDKITDKQKKNEECSQLNTALKEEY---D 1696

Query: 1521 EMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRD--EQLDNTMNK 1578
            ++++  +N    I  +  +   +Q  +    S+I +      D K+G D  E+      K
Sbjct: 1697 QLKSEFDN----IAVIESKAEEIQQKIDEIKSEIDQKRKEYQDIKEGNDLLEEAYTEKQK 1752

Query: 1579 EL 1580
            EL
Sbjct: 1753 EL 1754



 Score =  201 bits (490), Expect = 1e-49
 Identities = 317/1509 (21%), Positives = 672/1509 (44%), Gaps = 186/1509 (12%)

Query: 230  AEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEIS--LEHSKLAQELE-----QXX 282
            A  K +   L K ++ KD  I +L+ A  L  +   E+S  +E      EL+        
Sbjct: 181  ARSKVQMDSLRKQLQDKDEEIKNLKAATDLSNSRISELSGIIEGESKLSELKTPPSSPSY 240

Query: 283  XXXXXXXXXXXXLAKQSIEPSCEEKTEIE-EKGSLEIANMTELTKKIEL-------LEHL 334
                          KQ  +   + +TEIE E+G  E  N + L + I+L       L+ L
Sbjct: 241  RNFIDRGNYKDRRMKQLKDQLDQTETEIENEEGKTENLNYS-LNEMIDLVAERRRALQEL 299

Query: 335  NCQIRQTNKELENKLATMGTESKAVSSPSK----KGSPLISRKSGR--NTASKMKSPWSQ 388
                 +  ++L+ ++A + +E   +    K       P I +   R   T +K +    +
Sbjct: 300  RNSQGKDEEKLKKQIAKVESEKTKIEDEIKHLQEDEEPQIKKLKDRLDETTTKTQIAEKK 359

Query: 389  L---------SSETLNQDTDKKINK-----NEIAKLEMVIQSLNKDLVDKEYVISEKDTX 434
            L         S + L Q     I +     N+       +QS+N  + + +   ++ +  
Sbjct: 360  LGEMRKTIEDSRQKLAQRRQNLIERRKELTNDAENTNTELQSINNQIQEIDSEFNKLNGL 419

Query: 435  XXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLK---QELND 491
                      K + + +   + Q+ +                EIAK+ +QL+   +E ND
Sbjct: 420  VNKVQSDHSKKKSALQEQLAQKQKDLNDLKRKQAEEKASREAEIAKINDQLQKTMKEYND 479

Query: 492  --EIKDVNVKDLIEK----LKSAEEQITQLNDEIDAANKNMI----KVKSNHKLKLKQMQ 541
              + ++V++K+ I++    LK  E ++ +  +E+   N   +    K+    K K+ +M 
Sbjct: 480  LNQPQNVDLKNEIDQATKDLKELESRVNKKREELFGKNNQRVAELNKLNEQLKSKMDEMV 539

Query: 542  KTIDNFSKVSDSNK-EIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYK 600
            K         D ++ +   L  E+  +S ++++L++E   L++ + D++    ++  + +
Sbjct: 540  KADQELQSAKDEHEAKKNELKAEIESVSDEISKLKDE---LEV-IPDFEVDD-LKDQLNE 594

Query: 601  KMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEV-EDKLADISQL--QSDQVCS 657
             + E E L + ++K    L S    L  E+   +   D++ E+K     +L  +  ++  
Sbjct: 595  LLKEKEELEKEKIKNNDELNSSIIMLKDEIQKEKANKDKISEEKNKRDKELNDEKSKLQD 654

Query: 658  EIKSVHLEE---QIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYI 714
            E+ S+ L+E   + D L    ++L   +++ K+    +   I DL+  +  +  K ++  
Sbjct: 655  ELDSLQLDEIENENDQLFEEVEDLKSKVDDAKILYNDMVDKIDDLKQQRSKVEQKYKDLE 714

Query: 715  QENMDLTDKLEKMSAEKISELLAKINHEEQSKIQT---QFGIDA---KIQERDLYIENIE 768
            ++N + +D++EK+S E ISEL  K+++  Q K  T      +DA   +I ++    E I+
Sbjct: 715  KQNKEKSDEIEKVSKE-ISELKEKLDNLNQFKDNTPELHQKVDAMNEQIVKKSQENEKIQ 773

Query: 769  SELSKYKSRICRLE---ESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELV- 824
             E++K    +  LE   E I V+ D R +++ K D +   ++EK+K+  E     + L+ 
Sbjct: 774  EEMNKLNEELQHLENEMEEIEVVNDERETIQEKIDNIKQQIEEKKKSNEEIQDIMNLLIE 833

Query: 825  --NRLAVLMDHDRVVEKQLLEIEHENKELQ-------KKNQILLEENQNLQISLSDMQQH 875
              N     +D   +VE Q  EI    + LQ       K N  L E+N  LQ  L D+Q  
Sbjct: 834  AENDAQKELDDIEIVEAQSEEIRQRIQTLQDNLQDRKKLNNELTEQNNKLQKELKDLQNE 893

Query: 876  YNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLI--VQK-KKEIEDLEI-- 930
             +      + ++    +  + + Q+ + +S  +  T +++ LI  ++K  KE++++EI  
Sbjct: 894  LDQTELVNDDSESLNKKLDEIKEQINERKSQNENNTEQNEKLIEEIEKFAKELDEIEIIE 953

Query: 931  ----EFNTQI---ESAIRDKKVLNEKYEK---NIEYVTQLEAQ----LQEYKNN------ 970
                +   QI   +  I +K+  NE+ +K   ++E+  Q+  Q    +   KNN      
Sbjct: 954  DKSDKLQAQISELQKQIDEKQKNNEQTDKSNNDLEHELQITKQKLDSMSSVKNNSDYLKS 1013

Query: 971  -IENLNMNVEEL----NKMNLELIDKHVQ-KQQTQSPDYTEQYINEINKLNALLKQK--- 1021
             IEN+N  +E++    NK+  EL DK+ + ++ T   D +E+   +I+ +N  + ++   
Sbjct: 1014 EIENVNKEIEKIRDTNNKLKQELQDKNKELEEMTDIADNSEELKEKIDSVNEEITKRVAN 1073

Query: 1022 ----DEEIIALNQKINNAQVSYMSM--VSDYESKLAQFTTKLENMEEEMQRVSKQLLDSK 1075
                DE I  L++ + NA+    S+  V D    L       ++++E + ++S++  ++ 
Sbjct: 1074 NTTIDELIRHLHEDLKNAEAKLQSIPHVDDNTDSLQ------KSLDEVLAQISQKQREND 1127

Query: 1076 QHNEELQILVREQDDQIKELKETKLTFEMNIP-KTEGMIISSTIEPMSDDANNVDXXXXX 1134
            + N+E+  L++E++++  EL   +      IP K E   ISS IE +             
Sbjct: 1128 ELNDEISRLIQEKEEKTDELNNME-----TIPDKREE--ISSEIETVKSQIEE------- 1173

Query: 1135 XXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTEL--TGHDV-V 1191
                    K +  E+  +E   L E+   L   L +  T    LE +  E+  T  ++  
Sbjct: 1174 --------KKKNNEKIAEENKKLAEELENLRQTLSKMETSDQPLENIQKEIETTKQEISE 1225

Query: 1192 NQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQ 1251
             Q+++++LK +LEQ+  E+ +    ++E   +I + +D++  +  E+ K +  +++++  
Sbjct: 1226 KQKELDELKQELEQIKDEDQSKADEISEEIENIKTQIDEKNKKNEEIAKNN-EEKQSELD 1284

Query: 1252 KTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQ---NKLQDKEEHLRN 1308
            +   EL+  L   + + E++   ++ + +E   K    E    L    +KL+   E + N
Sbjct: 1285 EKLKELQ-DLEEIKDETEEINQQIEETQKEIETKKQQKENNNKLNEELDKLKQDLEQIEN 1343

Query: 1309 LQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQS-- 1366
            +++    +  +IE ++S+I D K                    L+ E +  + ++++S  
Sbjct: 1344 VEDNVEKLTEEIEKVKSDI-DSKHQLNNDIKEANEVVEEELNSLKEELEKIEPVEDKSDE 1402

Query: 1367 ----ILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLEL------THQLELKDSEI 1416
                I+ I +E    K ++             +ND + ++ E+      + +++ +   +
Sbjct: 1403 IRKEIVKIQKEIETKKATNCGISESNELLNKELNDLKNQLEEIAEEKDDSEEIKAEIENL 1462

Query: 1417 YQKTHEYTITLTQRNDEFENVRQQLVEYEKR------IEDLTYEKESELAILRLKMHENA 1470
            ++   E            EN++++L + ++       +ED   E  SE+  L+ ++ E  
Sbjct: 1463 HKSIEEKKEHNANTQQNNENMKEELSKLQEEFDQIEVVEDKAEEIHSEIEKLKSQIEEKN 1522

Query: 1471 NHYETMQKESEI--ERV----KLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQT 1524
                 +++ ++I  E +    K  +E++V+  +S  L+++V +L K LEE+ ++   +++
Sbjct: 1523 TTNNDIKEANDILNEELNNLQKQYDEIDVEEDKSEELSQKVTDLQKLLEEKKSQNETIKS 1582

Query: 1525 ALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTM--NKELLD 1582
              EN   E+ +L +E+ N++ +V +SS + +K +         + +Q + T   N+EL +
Sbjct: 1583 GNENILKELQSLQNELDNIE-VVSSSSEEGEKKIEKLKQMISDKQKQNEETTKHNEELDN 1641

Query: 1583 AVPRAELDL 1591
             +   E +L
Sbjct: 1642 QIKDLENEL 1650



 Score =  192 bits (469), Expect = 5e-47
 Identities = 300/1516 (19%), Positives = 672/1516 (44%), Gaps = 130/1516 (8%)

Query: 140  QLGDVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXX 199
            ++ D+   S  +KEK ++++    K     TTI +L   ++E  +  EAK ++       
Sbjct: 1045 EMTDIADNSEELKEKIDSVNEEITKRVANNTTIDELIRHLHEDLKNAEAKLQSIPHVDDN 1104

Query: 200  XXXXXXXXXXXXEDTKQQMTKMQE-----NFIAMEAEWKDEKQRLLKDIESKDVRISS-L 253
                            Q+  +  E     + +  E E K ++   ++ I  K   ISS +
Sbjct: 1105 TDSLQKSLDEVLAQISQKQRENDELNDEISRLIQEKEEKTDELNNMETIPDKREEISSEI 1164

Query: 254  EEANKLLEAAR---FEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCE-EKTE 309
            E     +E  +    +I+ E+ KLA+ELE               L  ++I+   E  K E
Sbjct: 1165 ETVKSQIEEKKKNNEKIAEENKKLAEELENLRQTLSKMETSDQPL--ENIQKEIETTKQE 1222

Query: 310  IEEKGSLEIANMTELTKKIE-LLEHLNCQIRQTNKELENKLATMGTESK----AVSSPSK 364
            I EK       + EL +++E + +    +  + ++E+EN    +  ++K       +  +
Sbjct: 1223 ISEKQK----ELDELKQELEQIKDEDQSKADEISEEIENIKTQIDEKNKKNEEIAKNNEE 1278

Query: 365  KGSPLISRKSGRNTASKMKSPWSQLS---SETLNQDTDKKINKNEIAKLEMVIQSLNKDL 421
            K S L  +        ++K    +++    ET  +   KK  K    KL   +  L +DL
Sbjct: 1279 KQSELDEKLKELQDLEEIKDETEEINQQIEETQKEIETKKQQKENNNKLNEELDKLKQDL 1338

Query: 422  VDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNT--EDVNEIA 479
               E + + +D            K  + ++ QL +    E   ++    N+  E++ +I 
Sbjct: 1339 ---EQIENVEDNVEKLTEEIEKVKSDIDSKHQL-NNDIKEANEVVEEELNSLKEELEKIE 1394

Query: 480  KVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAA---NKNMIKVKSNHKLK 536
             V+++   E+  EI  V ++  IE  K+    I++ N+ ++      KN ++  +  K  
Sbjct: 1395 PVEDK-SDEIRKEI--VKIQKEIETKKATNCGISESNELLNKELNDLKNQLEEIAEEKDD 1451

Query: 537  LKQMQKTIDNFSKVSDSNKEIVRLTEELH-HLSQKVAELEEEKGNLQLHLVDYDSGRMIE 595
             ++++  I+N  K  +  KE    T++ + ++ +++++L+EE    Q+ +V+ D    I 
Sbjct: 1452 SEEIKAEIENLHKSIEEKKEHNANTQQNNENMKEELSKLQEEFD--QIEVVE-DKAEEIH 1508

Query: 596  SDV--YKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEV---EDKLADISQL 650
            S++   K  IE +N     +K  + +      L +EL+ LQ++YDE+   EDK  ++SQ 
Sbjct: 1509 SEIEKLKSQIEEKNTTNNDIKEANDI------LNEELNNLQKQYDEIDVEEDKSEELSQK 1562

Query: 651  QSD--QVCSEIKSVH--LEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDI 706
             +D  ++  E KS +  ++   + +    + L   ++N+++         K +E  K+ I
Sbjct: 1563 VTDLQKLLEEKKSQNETIKSGNENILKELQSLQNELDNIEVVSSSSEEGEKKIEKLKQMI 1622

Query: 707  MNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSK-IQTQF-GIDAKIQERDLYI 764
             +K Q   +E     ++L+    +  +EL   I  +++S  +Q Q   I  KI ++    
Sbjct: 1623 SDK-QKQNEETTKHNEELDNQIKDLENELNEIIPVKDKSNDLQQQIEEIKDKITDKQKKN 1681

Query: 765  ENIESELSKYKSRICRLE---ESIAVMEDRRYSLERKADQLGSYLQEKQKAYSE------ 815
            E      +  K    +L+   ++IAV+E +   +++K D++ S + +K+K Y +      
Sbjct: 1682 EECSQLNTALKEEYDQLKSEFDNIAVIESKAEEIQQKIDEIKSEIDQKRKEYQDIKEGND 1741

Query: 816  -----YTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLS 870
                 YT ++ EL  ++ V+ D    ++  + EI  +    +  N      N+  +  L 
Sbjct: 1742 LLEEAYTEKQKEL-EQIEVVEDKTEDLQNLIDEITEQINSRKSNNLERQVSNETFEKQLG 1800

Query: 871  DMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTL---IVQKKKEIED 927
             ++Q  N L +  + ++  + E  + + +L  ++   +R++ E ++L   +++ + E+ D
Sbjct: 1801 QLKQELNDLPQTDDNSESLKEEIEETKKKLAMMKDEYQRMSDEDKSLTDELIRVESELND 1860

Query: 928  LEIEFNT-QIESAIR-DKKVLNEKYEKNI-EYVTQLEAQLQEYKNNIENLNMNVEELNKM 984
            LE + N  + E+ ++ +KK+ N+    ++   +  L+AQLQ+ +   E++    +E  ++
Sbjct: 1861 LENQKNVLENETIVKAEKKMQNDNTIMDLRNKIDTLKAQLQQQEKPQEDIEKLKKEYQEL 1920

Query: 985  NLELIDKHVQKQQTQSPDYTEQYINEINKL-NALLKQKDEEIIALNQKINN--AQVSYMS 1041
              +   K  Q ++  S  ++E  ++ + ++ + + K + +++ +L  +I +  AQ+   +
Sbjct: 1921 KFQFDAKVSQNKEEVS--HSENELHSLKEMYDKIEKVEQQQVDSLKSQILSVKAQIDDQN 1978

Query: 1042 MVS-DYESKLAQFTTKLENMEEEMQRVSKQLLDSK--QHNEELQILVREQDDQIKELKET 1098
              + + + ++ + T++  + + E+++   ++   +  + +EE++ L  E D++ K+ +E 
Sbjct: 1979 KKNEEMKKQIEKLTSEKSDAQNELEKAENKVDPDELVRLSEEIEELKLEADEKKKQNEEV 2038

Query: 1099 KLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKV--QEEEEFIQERSV 1156
            + + E  + K + ++ +   +  SD  N +D             +   Q+ +E I     
Sbjct: 2039 RSSLEEELSKYKEILENLKSDNQSDIHNQIDQIKDRINEKQQENEADNQKLQEIINNHKK 2098

Query: 1157 LQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLST 1216
            L E   K + E+Q+   +  +++  N E+       Q++IN++K KL+Q   EN++    
Sbjct: 2099 LLENMNKEHEEIQKQIEQ--EVDKNNKEID----QKQKEINEVKEKLQQAKKENED---D 2149

Query: 1217 VAELRSSISSA------VDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQ 1270
              EL+  I +       +   G    +L KQ + ++E + Q+   + + ++  +++K + 
Sbjct: 2150 KVELQRQIDNCGREIEKLQNAGDSEIDLLKQEIDKKEKERQQATEQKQHEIEMYKAKLQ- 2208

Query: 1271 LLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDE 1330
                     +   N      ++ +L+ K+  +E   +N  E    +++++++   E+E+E
Sbjct: 2209 -----HKEQENAVNAEKLHNEIENLKKKIDSQEMEYKNYNESLTKILDKLKVKLEEVEEE 2263

Query: 1331 KVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXX 1390
                                  R +N +  +   Q I  + EE   L++++         
Sbjct: 2264 N-RNEDERAEEVENLKAQIASKRKQNDAENEKLSQEINKLKEELQNLQENTEIEEMKQTV 2322

Query: 1391 XXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIED 1450
               +    +  V     Q ++K  +   +  E T  L + +DE + +R+Q       IE+
Sbjct: 2323 EDLK---TQISVFGDPEQEKIKLQKEIDELTEKTEKLAEADDENDKLREQ-------IEN 2372

Query: 1451 LTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNK 1510
            L   K  ++ I+ L   E+    E  Q   E+ ++K   E      +   L ++V +L+K
Sbjct: 2373 LKNVKSRDVEIIDLGEEEDG---ERQQLVEELNKLKEEYEQLQNTDDINDLKQEVIDLSK 2429

Query: 1511 ALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFAS---DTKQG 1567
             ++E  A   + QT  +  + E+  LN +I N+         +I+ H+       D KQ 
Sbjct: 2430 QIDEIKASNKDAQTKSDLLK-ELSQLNSQIENI-IQEEEDKEEIRSHIEEIKSLLDNKQS 2487

Query: 1568 RDEQLD-NTMNKELLD 1582
             +++ + + + K+L D
Sbjct: 2488 EEDEKELDDLKKQLED 2503



 Score =  188 bits (458), Expect = 1e-45
 Identities = 286/1440 (19%), Positives = 642/1440 (44%), Gaps = 138/1440 (9%)

Query: 212  EDTKQQMTKMQENFIAMEA------EWKDEKQRLLKDIESKDVRISSLEEANKLL----- 260
            E+ K++++K+QE F  +E       E   E ++L   IE K+   + ++EAN +L     
Sbjct: 1481 ENMKEELSKLQEEFDQIEVVEDKAEEIHSEIEKLKSQIEEKNTTNNDIKEANDILNEELN 1540

Query: 261  --EAARFEISLEHSKLAQELEQXXXXXXXXXXXXXX---LAKQSIEPSCEEKTEIE-EKG 314
              +    EI +E  K ++EL Q                   K   E   +E   ++ E  
Sbjct: 1541 NLQKQYDEIDVEEDK-SEELSQKVTDLQKLLEEKKSQNETIKSGNENILKELQSLQNELD 1599

Query: 315  SLEIANMT--ELTKKIELLEHL-------NCQIRQTNKELENKLATMGTESKAVSSPSKK 365
            ++E+ + +  E  KKIE L+ +       N +  + N+EL+N++  +  E   +     K
Sbjct: 1600 NIEVVSSSSEEGEKKIEKLKQMISDKQKQNEETTKHNEELDNQIKDLENELNEIIPVKDK 1659

Query: 366  GSPLISR----KSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDL 421
             + L  +    K       K     SQL++    +    K   + IA +E   + + + +
Sbjct: 1660 SNDLQQQIEEIKDKITDKQKKNEECSQLNTALKEEYDQLKSEFDNIAVIESKAEEIQQKI 1719

Query: 422  VDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDV-NEIAK 480
               + + SE D           G D L+ +   E Q+ +E   ++     TED+ N I +
Sbjct: 1720 ---DEIKSEIDQKRKEYQDIKEGND-LLEEAYTEKQKELEQIEVVE--DKTEDLQNLIDE 1773

Query: 481  VQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQM 540
            + EQ+    ++ ++     +  EK     +Q  +LND +   + N   +K   +   K++
Sbjct: 1774 ITEQINSRKSNNLERQVSNETFEKQLGQLKQ--ELND-LPQTDDNSESLKEEIEETKKKL 1830

Query: 541  QKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYK 600
                D + ++SD +K    LT+EL  +  ++ +LE +K  L+   +   + + +++D   
Sbjct: 1831 AMMKDEYQRMSDEDKS---LTDELIRVESELNDLENQKNVLENETI-VKAEKKMQND--N 1884

Query: 601  KMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKL-ADISQLQSDQVCSEI 659
             ++++ N  +T LKA  L + +K    +++  L+++Y E++ +  A +SQ + +   SE 
Sbjct: 1885 TIMDLRNKIDT-LKA-QLQQQEKPQ--EDIEKLKKEYQELKFQFDAKVSQNKEEVSHSEN 1940

Query: 660  KSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMD 719
            +   L+E  D +   +++    +++LK     +   I D     E++  +++    E  D
Sbjct: 1941 ELHSLKEMYDKIEKVEQQQ---VDSLKSQILSVKAQIDDQNKKNEEMKKQIEKLTSEKSD 1997

Query: 720  LTDKLEKMSAEKISELLAKINHE-EQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRI 778
              ++LEK   +   + L +++ E E+ K++     D K ++ +    ++E ELSKYK  +
Sbjct: 1998 AQNELEKAENKVDPDELVRLSEEIEELKLEA----DEKKKQNEEVRSSLEEELSKYKEIL 2053

Query: 779  CRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMD-----H 833
              L+       D +  +  + DQ+   + EKQ+       +  E++N    L++     H
Sbjct: 2054 ENLKS------DNQSDIHNQIDQIKDRINEKQQENEADNQKLQEIINNHKKLLENMNKEH 2107

Query: 834  DRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESES 893
            + + ++   E++  NKE+ +K + + E  + LQ +    +++ +  VE   + D    E 
Sbjct: 2108 EEIQKQIEQEVDKNNKEIDQKQKEINEVKEKLQQA---KKENEDDKVELQRQIDNCGREI 2164

Query: 894  TKYQ----TQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEF-NTQIESAIRDKKVLNE 948
             K Q    +++  L+  + +   E Q    QK+ EIE  + +  + + E+A+  +K+ NE
Sbjct: 2165 EKLQNAGDSEIDLLKQEIDKKEKERQQATEQKQHEIEMYKAKLQHKEQENAVNAEKLHNE 2224

Query: 949  KYEKNIEYVTQLEAQLQEYKNN-------IENLNMNVEELNKMN---------LELIDKH 992
               +N++   ++++Q  EYKN        ++ L + +EE+ + N         +E +   
Sbjct: 2225 I--ENLK--KKIDSQEMEYKNYNESLTKILDKLKVKLEEVEEENRNEDERAEEVENLKAQ 2280

Query: 993  VQKQQTQSPDYTEQYINEINKLNALLK--QKDEEIIALNQKINNAQVSYMSMVSDYESKL 1050
            +  ++ Q+    E+   EINKL   L+  Q++ EI  + Q + + +   +S+  D E + 
Sbjct: 2281 IASKRKQNDAENEKLSQEINKLKEELQNLQENTEIEEMKQTVEDLKTQ-ISVFGDPEQEK 2339

Query: 1051 AQFTTKLENMEEEMQRVSKQLLDSKQHNEELQIL--VREQDDQIKELKETK------LTF 1102
             +   +++ + E+ +++++   ++ +  E+++ L  V+ +D +I +L E +      L  
Sbjct: 2340 IKLQKEIDELTEKTEKLAEADDENDKLREQIENLKNVKSRDVEIIDLGEEEDGERQQLVE 2399

Query: 1103 EMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSA 1162
            E+N  K E   + +T     DD N++             +K   ++   Q +S L ++ +
Sbjct: 2400 ELNKLKEEYEQLQNT-----DDINDLKQEVIDLSKQIDEIKASNKDA--QTKSDLLKELS 2452

Query: 1163 KLNTELQECYTKIIQLETLNTELTGH-----DVVNQEQINQLKSKLEQLNTENDNLLSTV 1217
            +LN++++     IIQ E    E+  H      +++ +Q  + + +L+ L  + ++  S +
Sbjct: 2453 QLNSQIEN----IIQEEEDKEEIRSHIEEIKSLLDNKQSEEDEKELDDLKKQLEDKQSLI 2508

Query: 1218 AELRSSI--SSAVDQRGFEIAELWKQHLAQREADFQKTEH--ELRVQLSAFESKYEQLLD 1273
             +L+  I  +   +++  +  +  +Q       ++++     E R  L     + +QL+ 
Sbjct: 2509 NKLKEDIKLTKEENEKAQKNIDDLEQEFDDLNNEYEEESQFDEERKLLETEIERLKQLIS 2568

Query: 1274 SVQSSTQEETNKIVT-MEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKV 1332
              ++  +E+T+K+   +  +T   N L+D  E+ + LQ +  ++  QI  ++ E   ++ 
Sbjct: 2569 EKKTQNKEKTDKLFKEINDLTEELNSLEDDSEN-KELQSQIDELNEQINSVKEESNPQQT 2627

Query: 1333 AFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXX 1392
                               +  E ++ K  +E   L    ++ + ++ +           
Sbjct: 2628 KENLQKELDDLNNKLQQM-IEDEEENEKLKEEIDALKEELKDNKSQEENQQLKSQISELQ 2686

Query: 1393 XRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLT 1452
             ++   + ++ E  + L+   S+I Q  +E     ++R D+  ++ +++   +++I +  
Sbjct: 2687 EQIKQKQNEISETENSLK---SQISQLQNELKEKESERGDKSNSLYKEIDSLKEKINNQE 2743

Query: 1453 YEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKAL 1512
             E +++ + L   + +     + + +E+E  + K+ EE     +E   L ++   LNK L
Sbjct: 2744 IENKADSSQLSDLLKDLKKKLQELTEENETIKSKISEEKEKSKSEMAKLEEEKKSLNKEL 2803

Query: 1513 EE-EVAKTNEMQTALENQEIEIVTLNDEITNLQNM-VRASSSKIQKHVSFASDTKQGRDE 1570
            E     +  EM     +   E + L  +I   Q   +     K+ + +S  +D +  + E
Sbjct: 2804 ENVNDDEDKEMLEGEVSSLKETLNLKKQINEEQKQKLSQEKEKLTEELSQLNDNEDLKKE 2863



 Score =  169 bits (410), Expect = 7e-40
 Identities = 318/1582 (20%), Positives = 686/1582 (43%), Gaps = 155/1582 (9%)

Query: 57   AQKCLENAAL---VSKRIKEHRKATAELLGRPFVPGISESLANTLKQKEILMEKIKQYKE 113
            +QK  EN  L   +S+ I+E  + T EL     +P   E +++ +       E +K   E
Sbjct: 1120 SQKQRENDELNDEISRLIQEKEEKTDELNNMETIPDKREEISSEI-------ETVKSQIE 1172

Query: 114  LSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNALSVLQVKMKIMETTIL 173
              K+++  I                 +L ++    + ++  D  L  +Q +++  +  I 
Sbjct: 1173 EKKKNNEKIAEENKKLAE--------ELENLRQTLSKMETSDQPLENIQKEIETTKQEIS 1224

Query: 174  DLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWK 233
            + Q++++E  Q +E                        ++  ++  ++ +N    ++E  
Sbjct: 1225 EKQKELDELKQELEQIKDEDQSKADEISEEIENIKTQIDEKNKKNEEIAKNNEEKQSEL- 1283

Query: 234  DEKQRLLKDIES-KDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXX 292
            DEK + L+D+E  KD      EE N+ +E  + EI  +     Q+ E             
Sbjct: 1284 DEKLKELQDLEEIKD----ETEEINQQIEETQKEIETKK----QQKENNNKLNEELDKLK 1335

Query: 293  XXLAK-QSIEPSCEEKTEIEEKGSLEIANMTELTKKI-ELLEHLNCQIRQTNKELENKLA 350
              L + +++E + E+ TE  EK   +I +  +L   I E  E +  ++    +ELE K+ 
Sbjct: 1336 QDLEQIENVEDNVEKLTEEIEKVKSDIDSKHQLNNDIKEANEVVEEELNSLKEELE-KIE 1394

Query: 351  TMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQD-TDKKINKNEIAK 409
             +  +S  +     K    I  K   N            S+E LN++  D K    EIA+
Sbjct: 1395 PVEDKSDEIRKEIVKIQKEIETKKATNCGISE-------SNELLNKELNDLKNQLEEIAE 1447

Query: 410  LEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVG 469
             +   + +  ++ +    I EK                 +++LQ E  Q      +  V 
Sbjct: 1448 EKDDSEEIKAEIENLHKSIEEKKEHNANTQQNNENMKEELSKLQEEFDQ------IEVVE 1501

Query: 470  TNTEDVN-EIAKVQEQLKQE--LNDEIKDVNVKDLI-EKLKSAEEQITQLNDEIDAANKN 525
               E+++ EI K++ Q++++   N++IK+ N  D++ E+L + ++Q  +++ E D + + 
Sbjct: 1502 DKAEEIHSEIEKLKSQIEEKNTTNNDIKEAN--DILNEELNNLQKQYDEIDVEEDKSEEL 1559

Query: 526  MIKVKSNHKLKLKQMQKTIDNFSKVSDSN--KEIVRLTEELHHLSQKVAELEEEKGNLQL 583
              KV    KL   + +K+ +   K  + N  KE+  L  EL ++  +V     E+G  ++
Sbjct: 1560 SQKVTDLQKLL--EEKKSQNETIKSGNENILKELQSLQNELDNI--EVVSSSSEEGEKKI 1615

Query: 584  HLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLV---QELHILQQKYDEV 640
              +     +MI SD  K+  E     E     I  LE++  +++    + + LQQ+ +E+
Sbjct: 1616 EKLK----QMI-SDKQKQNEETTKHNEELDNQIKDLENELNEIIPVKDKSNDLQQQIEEI 1670

Query: 641  EDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLE 700
            +DK+ D  + + ++ CS++ +  L+E+ D L +    +A VIE+     E++   I ++ 
Sbjct: 1671 KDKITD--KQKKNEECSQLNTA-LKEEYDQLKSEFDNIA-VIES---KAEEIQQKIDEI- 1722

Query: 701  NDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQE- 759
              K +I  K + Y Q+  +  D LE+   EK  EL  +I   E      Q  ID   ++ 
Sbjct: 1723 --KSEIDQKRKEY-QDIKEGNDLLEEAYTEKQKEL-EQIEVVEDKTEDLQNLIDEITEQI 1778

Query: 760  RDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQ 819
                  N+E ++S         E+ +  ++     L +  D   S  +E ++   +  + 
Sbjct: 1779 NSRKSNNLERQVSNET-----FEKQLGQLKQELNDLPQTDDNSESLKEEIEETKKKLAMM 1833

Query: 820  EDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNAL 879
            +DE       + D D+ +  +L+ +E E  +L+ +  +L  EN+ + +      Q+ N +
Sbjct: 1834 KDEYQR----MSDEDKSLTDELIRVESELNDLENQKNVL--ENETI-VKAEKKMQNDNTI 1886

Query: 880  VEKANRTDLAESE---STKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQI 936
            ++  N+ D  +++     K Q  +  L+   + +  +    + Q K+E+   E E ++  
Sbjct: 1887 MDLRNKIDTLKAQLQQQEKPQEDIEKLKKEYQELKFQFDAKVSQNKEEVSHSENELHSLK 1946

Query: 937  ESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQ 996
            E   + +KV  ++ +     +  ++AQ+ +     E +   +E+L     +  ++  + +
Sbjct: 1947 EMYDKIEKVEQQQVDSLKSQILSVKAQIDDQNKKNEEMKKQIEKLTSEKSDAQNELEKAE 2006

Query: 997  QTQSPDYTEQYINEIN--KLNALLKQKDEEII--ALNQKINNAQVSYMSMVSDYES---- 1048
                PD   +   EI   KL A  K+K  E +  +L ++++  +    ++ SD +S    
Sbjct: 2007 NKVDPDELVRLSEEIEELKLEADEKKKQNEEVRSSLEEELSKYKEILENLKSDNQSDIHN 2066

Query: 1049 KLAQFTTKLENMEEEMQRVSKQLLD-SKQHNEELQILVREQDDQIKELKE--TKLTFEMN 1105
            ++ Q   ++   ++E +  +++L +    H + L+ + +E ++  K++++   K   E++
Sbjct: 2067 QIDQIKDRINEKQQENEADNQKLQEIINNHKKLLENMNKEHEEIQKQIEQEVDKNNKEID 2126

Query: 1106 IPKTEGMIISSTIE--PMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAK 1163
              + E   +   ++     ++ + V+             K+Q   +   E  +L+++  K
Sbjct: 2127 QKQKEINEVKEKLQQAKKENEDDKVELQRQIDNCGREIEKLQNAGD--SEIDLLKQEIDK 2184

Query: 1164 LNTELQEC-YTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRS 1222
               E Q+    K  ++E    +L   +  N     +L +++E L  + D+          
Sbjct: 2185 KEKERQQATEQKQHEIEMYKAKLQHKEQENAVNAEKLHNEIENLKKKIDSQEMEYKNYNE 2244

Query: 1223 SISSAVDQRGFEIAELWKQHL--AQREADFQKTEHEL---RVQLSAFESKYEQLLDSVQS 1277
            S++  +D+   ++ E+ +++    +R  + +  + ++   R Q  A   K  Q ++ ++ 
Sbjct: 2245 SLTKILDKLKVKLEEVEEENRNEDERAEEVENLKAQIASKRKQNDAENEKLSQEINKLKE 2304

Query: 1278 STQ--EETNKIVTMEQ-VTSLQNKLQ---DKEEHLRNLQEKYADVINQIE-ILRSEIEDE 1330
              Q  +E  +I  M+Q V  L+ ++    D E+    LQ++  ++  + E +  ++ E++
Sbjct: 2305 ELQNLQENTEIEEMKQTVEDLKTQISVFGDPEQEKIKLQKEIDELTEKTEKLAEADDEND 2364

Query: 1331 KVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXX 1390
            K+                  DL  E    +Q   + +  + EE  QL+ +          
Sbjct: 2365 KLREQIENLKNVKSRDVEIIDLGEEEDGERQQLVEELNKLKEEYEQLQNTDD-------- 2416

Query: 1391 XXXRVNDAEAKVLELTHQL-ELKDSEIYQKTHEYTI-TLTQRNDEFENVRQQLVEYEKRI 1448
                +ND + +V++L+ Q+ E+K S    +T    +  L+Q N + EN+ Q   E E + 
Sbjct: 2417 ----INDLKQEVIDLSKQIDEIKASNKDAQTKSDLLKELSQLNSQIENIIQ---EEEDKE 2469

Query: 1449 EDLTYEKESELAILRLKMHENANHYETMQKESE---------IERVKLIEELNVKITESV 1499
            E  ++ +E +  +   +  E+    + ++K+ E          E +KL +E N K  +++
Sbjct: 2470 EIRSHIEEIKSLLDNKQSEEDEKELDDLKKQLEDKQSLINKLKEDIKLTKEENEKAQKNI 2529

Query: 1500 -SLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHV 1558
              L ++  +LN   EEE ++ +E +  LE    EI  L   I+  +   +  + K+ K +
Sbjct: 2530 DDLEQEFDDLNNEYEEE-SQFDEERKLLET---EIERLKQLISEKKTQNKEKTDKLFKEI 2585

Query: 1559 SFASDTKQGRDEQLDNTMNKEL 1580
               +D  +  +   D++ NKEL
Sbjct: 2586 ---NDLTEELNSLEDDSENKEL 2604



 Score =  168 bits (409), Expect = 1e-39
 Identities = 302/1491 (20%), Positives = 645/1491 (43%), Gaps = 139/1491 (9%)

Query: 149  NTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQI---IEAK---NKATTXXXXXXXX 202
            NTI +  N +  L+ +++  E    D+++   E  ++    +AK   NK           
Sbjct: 1884 NTIMDLRNKIDTLKAQLQQQEKPQEDIEKLKKEYQELKFQFDAKVSQNKEEVSHSENELH 1943

Query: 203  XXXXXXXXXEDTKQQMT-KMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLE 261
                     E  +QQ    ++   ++++A+  D+ ++  +  +  +   S   +A   LE
Sbjct: 1944 SLKEMYDKIEKVEQQQVDSLKSQILSVKAQIDDQNKKNEEMKKQIEKLTSEKSDAQNELE 2003

Query: 262  AARFEISLEHS-KLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIAN 320
             A  ++  +   +L++E+E+              + + S+E    +  EI E  +L+  N
Sbjct: 2004 KAENKVDPDELVRLSEEIEELKLEADEKKKQNEEV-RSSLEEELSKYKEILE--NLKSDN 2060

Query: 321  MTELTKKIELLEHLNCQIRQTNKELENKLATM-GTESKAVSSPSKKGSPL---ISRKSGR 376
             +++  +I+ ++    + +Q N+    KL  +     K + + +K+   +   I ++  +
Sbjct: 2061 QSDIHNQIDQIKDRINEKQQENEADNQKLQEIINNHKKLLENMNKEHEEIQKQIEQEVDK 2120

Query: 377  NTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXX 436
            N   ++     +++         KK N+++  +L+  I +  ++ ++K     + +    
Sbjct: 2121 NN-KEIDQKQKEINEVKEKLQQAKKENEDDKVELQRQIDNCGRE-IEKLQNAGDSEIDLL 2178

Query: 437  XXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHV----GTNTEDV-NEIAKVQEQL-KQELN 490
                    K+   A  Q +H+  M    L H       N E + NEI  +++++  QE+ 
Sbjct: 2179 KQEIDKKEKERQQATEQKQHEIEMYKAKLQHKEQENAVNAEKLHNEIENLKKKIDSQEME 2238

Query: 491  DEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSK- 549
             +  + ++  +++KLK   E++ + N   D   + +  +K+    K KQ     +  S+ 
Sbjct: 2239 YKNYNESLTKILDKLKVKLEEVEEENRNEDERAEEVENLKAQIASKRKQNDAENEKLSQE 2298

Query: 550  VSDSNKEIVRLTE--ELHHLSQKVAEL----------EEEKGNLQLHLVDYD--SGRMIE 595
            ++   +E+  L E  E+  + Q V +L          E+EK  LQ  + +    + ++ E
Sbjct: 2299 INKLKEELQNLQENTEIEEMKQTVEDLKTQISVFGDPEQEKIKLQKEIDELTEKTEKLAE 2358

Query: 596  SDVYKKMI--EMENLAETRLKAISLLE------SQKFDLVQELHILQQKYDEVEDKLADI 647
            +D     +  ++ENL   + + + +++       ++  LV+EL+ L+++Y+++++   DI
Sbjct: 2359 ADDENDKLREQIENLKNVKSRDVEIIDLGEEEDGERQQLVEELNKLKEEYEQLQNT-DDI 2417

Query: 648  SQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIM 707
            + L+ + +        L +QID + AS K+     + LK +  QL   I+++  ++ED  
Sbjct: 2418 NDLKQEVI-------DLSKQIDEIKASNKDAQTKSDLLK-ELSQLNSQIENIIQEEED-K 2468

Query: 708  NKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKI--QERDLYIE 765
             +++++I+E   L D  +    EK  + L K   ++QS I  +   D K+  +E +   +
Sbjct: 2469 EEIRSHIEEIKSLLDNKQSEEDEKELDDLKKQLEDKQSLIN-KLKEDIKLTKEENEKAQK 2527

Query: 766  NIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVN 825
            NI+    ++       EE     E+R+  LE + ++L   + EK+    E T   D+L  
Sbjct: 2528 NIDDLEQEFDDLNNEYEEESQFDEERKL-LETEIERLKQLISEKKTQNKEKT---DKLFK 2583

Query: 826  RLAVLMDHDRVVEKQLLEIEHENKELQKK--------NQILLEEN-----QNLQISLSDM 872
             +     +D   E   LE + ENKELQ +        N +  E N     +NLQ  L D+
Sbjct: 2584 EI-----NDLTEELNSLEDDSENKELQSQIDELNEQINSVKEESNPQQTKENLQKELDDL 2638

Query: 873  QQHYNALVEKANRTDLAESESTKYQTQLRDLESN-----LKRITHEHQTLIVQKKKEIED 927
                  ++E     +  + E    + +L+D +S      LK    E Q  I QK+ EI +
Sbjct: 2639 NNKLQQMIEDEEENEKLKEEIDALKEELKDNKSQEENQQLKSQISELQEQIKQKQNEISE 2698

Query: 928  LEIEFNTQIESAIRD-KKVLNEKYEKNIEYVTQLEAQLQEYKNN-IENLNMNVEELNKMN 985
             E    +QI     + K+  +E+ +K+     ++++  ++  N  IEN   +  +L+ + 
Sbjct: 2699 TENSLKSQISQLQNELKEKESERGDKSNSLYKEIDSLKEKINNQEIEN-KADSSQLSDL- 2756

Query: 986  LELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSD 1045
            L+ + K +Q+   ++     +   E  K  + + + +EE  +LN+++ N        + +
Sbjct: 2757 LKDLKKKLQELTEENETIKSKISEEKEKSKSEMAKLEEEKKSLNKELENVNDDEDKEMLE 2816

Query: 1046 YESKLAQFTTKLENM--EEEMQRVSKQL------LDSKQHNEELQILVREQDDQIKELK- 1096
             E    + T  L+    EE+ Q++S++       L     NE+L+  + ++ +++++LK 
Sbjct: 2817 GEVSSLKETLNLKKQINEEQKQKLSQEKEKLTEELSQLNDNEDLKKEIEQKKEELEKLKN 2876

Query: 1097 ETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSV 1156
            ++ L  E+   K +    S    P                     L   E+    Q+ + 
Sbjct: 2877 DSSLLQELQDLKKQIEEKSEKQNPELLKQIEDLKKEISEKESENDLITGEKNTVEQQYNK 2936

Query: 1157 LQEQSAKLNTELQECYTKIIQLETLNTELTGHD----VVNQEQINQLKSKLEQLNTENDN 1212
            L EQ   L + ++    K+  L     EL+  +    + N+++  ++K  +E++  + + 
Sbjct: 2937 LVEQRKYLESTMEAAKKKVSDLRQQCDELSMKNNQFRIDNEKEFQEIKKSIEEIKGQREQ 2996

Query: 1213 LLSTVAELRSSISSAVDQRGFEIAELWKQHL--AQREADFQKTEHELRVQLSAFESKYEQ 1270
            L     E +        +R  E   L +Q L  AQ++ D +K ++E  +++ + + K   
Sbjct: 2997 LAKKHNEDK--------RRAREYNTLARQKLTDAQQKLDAEKAKNENLLKMMSEQEKTVS 3048

Query: 1271 LLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDE 1330
             L+  +S   E+ NK +  +Q+TS  +  QDK E LR  +E       +++ L  E+  +
Sbjct: 3049 NLEK-ESEDLEQKNKELE-QQMTSTGDFSQDKIEELRKKKE-------ELQKLNDELSQK 3099

Query: 1331 KVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXX 1390
            +                    L  E +S K   E     + +E+ +++K           
Sbjct: 3100 Q----KQNIEQSNSLQNEKVTLSNEIESLKSSTEA----MEKESTEMEKKLEEDKGIISE 3151

Query: 1391 XXXRVNDAEAKVLEL---THQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKR 1447
                  D E K  E    + +L+ + +E+ +K  + T   T  ND+  ++   +   E+R
Sbjct: 3152 KSKEKEDLEKKSKEQQEKSDKLKQEVAELQEKAKKITTENTDLNDKITDLEISISNAERR 3211

Query: 1448 IEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITE-SVSLNKQVA 1506
             +DL  E E   A   L+  E        +K+ E+  +K   + N++  E S+SL +Q  
Sbjct: 3212 KKDLEEEIEKSSA-KSLQEKEKELEEIAEKKKKEVREMKKQHKQNIRSLESSISLLEQDI 3270

Query: 1507 ELNKALEE-EVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQK 1556
               K+LEE + +     Q  L+  + ++  L  +   L++++    S+++K
Sbjct: 3271 ---KSLEEIQNSSKKSEQEGLQLLDEKVADLKIKKFELEDIIADRDSELKK 3318



 Score =  158 bits (384), Expect = 1e-36
 Identities = 333/1645 (20%), Positives = 695/1645 (42%), Gaps = 189/1645 (11%)

Query: 53   KFERAQKCLENAALVSKRIKEHRKATAELLGRPFVPGISESLANTLKQKEILMEKIKQYK 112
            + +  Q  L+N  +VS   +E  K   +L  +  +    +    T K  E L  +IK  +
Sbjct: 1590 ELQSLQNELDNIEVVSSSSEEGEKKIEKL--KQMISDKQKQNEETTKHNEELDNQIKDLE 1647

Query: 113  -ELSK----RSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNALSVLQVKMKI 167
             EL++    +  +  ++               +  + + L+  +KE+ + L      + +
Sbjct: 1648 NELNEIIPVKDKSNDLQQQIEEIKDKITDKQKKNEECSQLNTALKEEYDQLKSEFDNIAV 1707

Query: 168  METTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIA 227
            +E+   ++Q+KI+E    I+ K K                    E+   +  K  E    
Sbjct: 1708 IESKAEEIQQKIDEIKSEIDQKRKE--------YQDIKEGNDLLEEAYTEKQKELEQIEV 1759

Query: 228  MEAEWKDEKQ---RLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXX 284
            +E + +D +     + + I S+       + +N+  E    ++  E + L Q  +     
Sbjct: 1760 VEDKTEDLQNLIDEITEQINSRKSNNLERQVSNETFEKQLGQLKQELNDLPQTDDNSESL 1819

Query: 285  XXXXXXXXXXLAKQSIE---PSCEEKTEIEEKGSLEIANMTELTKKIELLEH-------L 334
                      LA    E    S E+K+  +E   +E + + +L  +  +LE+        
Sbjct: 1820 KEEIEETKKKLAMMKDEYQRMSDEDKSLTDELIRVE-SELNDLENQKNVLENETIVKAEK 1878

Query: 335  NCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETL 394
              Q   T  +L NK+ T+  + +    P +    L  +K  +    +  +  SQ   E  
Sbjct: 1879 KMQNDNTIMDLRNKIDTLKAQLQQQEKPQEDIEKL--KKEYQELKFQFDAKVSQNKEEVS 1936

Query: 395  NQDTDKKINKNEIAKLEMV----IQSLNKDLVDKEYVISE--KDTXXXXXXXXXXGKDTL 448
            + + +    K    K+E V    + SL   ++  +  I +  K              +  
Sbjct: 1937 HSENELHSLKEMYDKIEKVEQQQVDSLKSQILSVKAQIDDQNKKNEEMKKQIEKLTSEKS 1996

Query: 449  IAQLQLEHQQHMEGPS-LIHVGTNTEDV----NEIAKVQEQLKQELNDEIKDVNVKDLIE 503
             AQ +LE  ++   P  L+ +    E++    +E  K  E+++  L +E+     K+++E
Sbjct: 1997 DAQNELEKAENKVDPDELVRLSEEIEELKLEADEKKKQNEEVRSSLEEELS--KYKEILE 2054

Query: 504  KLKSAEE-----QITQLNDEI-------DAANKNMIKVKSNHKLKLKQMQKTIDNFSK-- 549
             LKS  +     QI Q+ D I       +A N+ + ++ +NHK  L+ M K  +   K  
Sbjct: 2055 NLKSDNQSDIHNQIDQIKDRINEKQQENEADNQKLQEIINNHKKLLENMNKEHEEIQKQI 2114

Query: 550  ---VSDSNKEIVRLTEELHHLSQKV--AELEEEKGNLQLHLVDYDSGRMIES-------- 596
               V  +NKEI +  +E++ + +K+  A+ E E   ++L     + GR IE         
Sbjct: 2115 EQEVDKNNKEIDQKQKEINEVKEKLQQAKKENEDDKVELQRQIDNCGREIEKLQNAGDSE 2174

Query: 597  ------DVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQK-YDEVED--KLADI 647
                  ++ KK  E +   E +   I + +++     QE  +  +K ++E+E+  K  D 
Sbjct: 2175 IDLLKQEIDKKEKERQQATEQKQHEIEMYKAKLQHKEQENAVNAEKLHNEIENLKKKIDS 2234

Query: 648  SQLQ----SDQVCSEIKSVHLE-EQIDALSASKKELALVIENLKLDKEQLYGTIKDLEND 702
             +++    ++ +   +  + ++ E+++  + ++ E A  +ENLK           D EN+
Sbjct: 2235 QEMEYKNYNESLTKILDKLKVKLEEVEEENRNEDERAEEVENLKAQIASKRKQ-NDAENE 2293

Query: 703  K-EDIMNKLQNYIQENMDLTDKLE-KMSAEKISELLAKINHEEQSKIQTQFGIDAKIQER 760
            K    +NKL+  +Q   + T+  E K + E +   ++     EQ KI+ Q  ID ++ E+
Sbjct: 2294 KLSQEINKLKEELQNLQENTEIEEMKQTVEDLKTQISVFGDPEQEKIKLQKEID-ELTEK 2352

Query: 761  DLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKAD-QLGSYLQEKQKAYSEYT-I 818
               +   + E  K + +I  L+ ++   +     L  + D +    ++E  K   EY  +
Sbjct: 2353 TEKLAEADDENDKLREQIENLK-NVKSRDVEIIDLGEEEDGERQQLVEELNKLKEEYEQL 2411

Query: 819  QEDELVNRLAV-LMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYN 877
            Q  + +N L   ++D    + KQ+ EI+  NK+ Q K+ +L E +Q             N
Sbjct: 2412 QNTDDINDLKQEVID----LSKQIDEIKASNKDAQTKSDLLKELSQ------------LN 2455

Query: 878  ALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIE 937
            + +E   + +  + E   +  +++ L  N +  + E +  +   KK++ED +   N +++
Sbjct: 2456 SQIENIIQEEEDKEEIRSHIEEIKSLLDNKQ--SEEDEKELDDLKKQLEDKQSLIN-KLK 2512

Query: 938  SAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEE--LNKMNLELIDKHVQK 995
              I+  K  NEK +KNI+    LE +  +  N  E  +   EE  L +  +E + + + +
Sbjct: 2513 EDIKLTKEENEKAQKNID---DLEQEFDDLNNEYEEESQFDEERKLLETEIERLKQLISE 2569

Query: 996  QQTQSPDYTEQYINEIN----KLNALL-----KQKDEEIIALNQKIN------NAQVSYM 1040
            ++TQ+ + T++   EIN    +LN+L      K+   +I  LN++IN      N Q +  
Sbjct: 2570 KKTQNKEKTDKLFKEINDLTEELNSLEDDSENKELQSQIDELNEQINSVKEESNPQQTKE 2629

Query: 1041 SM---VSDYESKLAQFTT---KLENMEEEMQRVSKQLLDSK--QHNEELQILVREQDDQI 1092
            ++   + D  +KL Q      + E ++EE+  + ++L D+K  + N++L+  + E  +QI
Sbjct: 2630 NLQKELDDLNNKLQQMIEDEEENEKLKEEIDALKEELKDNKSQEENQQLKSQISELQEQI 2689

Query: 1093 K----ELKETKLTFEMNIPKTEGMI-------------ISSTIEPMSDDANNVDXXXXXX 1135
            K    E+ ET+ + +  I + +  +             +   I+ + +  NN +      
Sbjct: 2690 KQKQNEISETENSLKSQISQLQNELKEKESERGDKSNSLYKEIDSLKEKINNQEIENKAD 2749

Query: 1136 XXXXXXLKVQEEEEFIQERSVLQEQ-SAKLNTELQECYTKIIQLE----TLNTELTGHDV 1190
                  L +++ ++ +QE +   E   +K++ E ++  +++ +LE    +LN EL   +V
Sbjct: 2750 SSQLSDL-LKDLKKKLQELTEENETIKSKISEEKEKSKSEMAKLEEEKKSLNKEL--ENV 2806

Query: 1191 VNQEQINQLKSKLEQLNTENDNLLSTV-AELRSSISSAVDQRGFEIAELWKQHLAQREAD 1249
             + E    L+ ++  L  E  NL   +  E +  +S   ++   E+++L      ++E +
Sbjct: 2807 NDDEDKEMLEGEVSSLK-ETLNLKKQINEEQKQKLSQEKEKLTEELSQLNDNEDLKKEIE 2865

Query: 1250 FQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEH---- 1305
             +K E E     S+   + + L   ++  ++++  ++  ++Q+  L+ ++ +KE      
Sbjct: 2866 QKKEELEKLKNDSSLLQELQDLKKQIEEKSEKQNPEL--LKQIEDLKKEISEKESENDLI 2923

Query: 1306 ---LRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQM 1362
                  ++++Y  ++ Q + L S +E  K                     R +N+   Q 
Sbjct: 2924 TGEKNTVEQQYNKLVEQRKYLESTMEAAKKKVSDLRQQCDELSMKNN-QFRIDNEKEFQE 2982

Query: 1363 QEQSILNINEENAQLKKS----SXXXXXXXXXXXXRVNDAEAKV--LELTHQLELKDSEI 1416
             ++SI  I  +  QL K                  ++ DA+ K+   +  ++  LK    
Sbjct: 2983 IKKSIEEIKGQREQLAKKHNEDKRRAREYNTLARQKLTDAQQKLDAEKAKNENLLKMMSE 3042

Query: 1417 YQKT----HEYTITLTQRNDEFENVRQQLVEYEK-RIEDLTYEKESELAILRLKMHENAN 1471
             +KT     + +  L Q+N E E       ++ + +IE+L  +KE EL  L  ++ +   
Sbjct: 3043 QEKTVSNLEKESEDLEQKNKELEQQMTSTGDFSQDKIEELRKKKE-ELQKLNDELSQKQK 3101

Query: 1472 HYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEI 1531
                     + E+V L  E+    + + ++ K+  E+ K LEE+    +E     E+ E 
Sbjct: 3102 QNIEQSNSLQNEKVTLSNEIESLKSSTEAMEKESTEMEKKLEEDKGIISEKSKEKEDLEK 3161

Query: 1532 EIVTLNDEITNLQNMVRASSSKIQK 1556
            +     ++   L+  V     K +K
Sbjct: 3162 KSKEQQEKSDKLKQEVAELQEKAKK 3186



 Score =  153 bits (371), Expect = 4e-35
 Identities = 249/1290 (19%), Positives = 534/1290 (41%), Gaps = 95/1290 (7%)

Query: 321  MTELTKKIELLEHLNCQIRQTNKELENKLATMGTE---SKAVSSPSKKGSPLISRKSGRN 377
            + E ++++  LEH N  +   NKEL+ K  +   E   +  ++         I  +    
Sbjct: 65   LKEQSQRMIELEHQNESLEYENKELKAKTISFVGEFPNTSGINQADDSNETEIKIRKLMR 124

Query: 378  TASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXX 437
            T +K +   + L  E  N++  +      + KL         D      +I +       
Sbjct: 125  TINKQRRDIADL--EQKNKELQEAATNGPLMKLPASEGGPGLDETKSALLIKQ---LYRE 179

Query: 438  XXXXXXGKDTLIAQLQLEHQQHMEGPSLIHV-GTNTEDVNEIAKVQEQLKQELNDEIKDV 496
                    D+L  QLQ + ++     +   +  +   +++ I + + +L  EL       
Sbjct: 180  NARSKVQMDSLRKQLQDKDEEIKNLKAATDLSNSRISELSGIIEGESKL-SELKTPPSSP 238

Query: 497  NVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKE 556
            + ++ I++    + ++ QL D++D     +     N + K + +  ++   +++ D   E
Sbjct: 239  SYRNFIDRGNYKDRRMKQLKDQLDQTETEI----ENEEGKTENLNYSL---NEMIDLVAE 291

Query: 557  IVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAI 616
              R  +EL +   K    +EEK   Q+          +ES+  K   E+++L E     I
Sbjct: 292  RRRALQELRNSQGK----DEEKLKKQI--------AKVESEKTKIEDEIKHLQEDEEPQI 339

Query: 617  SLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEI-KSVHLEEQIDALSASK 675
              L+ +  +   +  I ++K  E+   + D  Q  + +  + I +   L    +  +   
Sbjct: 340  KKLKDRLDETTTKTQIAEKKLGEMRKTIEDSRQKLAQRRQNLIERRKELTNDAENTNTEL 399

Query: 676  KELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYI-QENMDLTDKLEKMSAEKISE 734
            + +   I+ +  +  +L G +  +++D     + LQ  + Q+  DL D   K + EK S 
Sbjct: 400  QSINNQIQEIDSEFNKLNGLVNKVQSDHSKKKSALQEQLAQKQKDLNDLKRKQAEEKASR 459

Query: 735  --LLAKINHE------EQSKIQTQFGIDAK--IQERDLYIENIESELSKYKSRIC-RLEE 783
               +AKIN +      E + +     +D K  I +    ++ +ES ++K +  +  +  +
Sbjct: 460  EAEIAKINDQLQKTMKEYNDLNQPQNVDLKNEIDQATKDLKELESRVNKKREELFGKNNQ 519

Query: 784  SIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLE 843
             +A +      L+ K D++    QE Q A  E+  +++EL   +  + D    ++ +L  
Sbjct: 520  RVAELNKLNEQLKSKMDEMVKADQELQSAKDEHEAKKNELKAEIESVSDEISKLKDELEV 579

Query: 844  I-EHENKELQKKNQILLEENQNLQISLSDMQQHYNALV---------EKANRTDLAESES 893
            I + E  +L+ +   LL+E + L+          N+ +         EKAN+  ++E E 
Sbjct: 580  IPDFEVDDLKDQLNELLKEKEELEKEKIKNNDELNSSIIMLKDEIQKEKANKDKISE-EK 638

Query: 894  TKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKN 953
             K   +L D +S L+    E  +L + + +   D   E    ++S + D K+L       
Sbjct: 639  NKRDKELNDEKSKLQ---DELDSLQLDEIENENDQLFEEVEDLKSKVDDAKILYNDMVDK 695

Query: 954  IEYVTQLEAQLQEYKNNIENLNM-NVEELNKMNLELID-KHVQKQQTQSPDYTEQYINEI 1011
            I+ + Q  +++++   ++E  N    +E+ K++ E+ + K       Q  D T +   ++
Sbjct: 696  IDDLKQQRSKVEQKYKDLEKQNKEKSDEIEKVSKEISELKEKLDNLNQFKDNTPELHQKV 755

Query: 1012 NKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQL 1071
            + +N  + +K +E   + +++N        + ++ E ++     + E ++E++  + +Q+
Sbjct: 756  DAMNEQIVKKSQENEKIQEEMNKLNEELQHLENEME-EIEVVNDERETIQEKIDNIKQQI 814

Query: 1072 LDSKQHNEELQ----ILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANN 1127
             + K+ NEE+Q    +L+  ++D  KEL       ++ I + +   I   I+ + D  N 
Sbjct: 815  EEKKKSNEEIQDIMNLLIEAENDAQKELD------DIEIVEAQSEEIRQRIQTLQD--NL 866

Query: 1128 VDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTG 1187
             D             K+Q+E + +Q      +Q+  +N + +    K+ +++    E   
Sbjct: 867  QDRKKLNNELTEQNNKLQKELKDLQNE---LDQTELVNDDSESLNKKLDEIKEQINERKS 923

Query: 1188 HDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQRE 1247
             +  N EQ  +L  ++E+   E D  +  + +    + + + +   +I E  K +  Q +
Sbjct: 924  QNENNTEQNEKLIEEIEKFAKELDE-IEIIEDKSDKLQAQISELQKQIDEKQKNN-EQTD 981

Query: 1248 ADFQKTEHELRVQLSAFESKYEQLLDS-VQSSTQEETNKIVTMEQVTSLQNKLQDKEEHL 1306
                  EHEL++     +S      +S    S  E  NK   +E++    NKL+ + +  
Sbjct: 982  KSNNDLEHELQITKQKLDSMSSVKNNSDYLKSEIENVNK--EIEKIRDTNNKLKQELQDK 1039

Query: 1307 RNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQS 1366
                E+  D+ +  E L+ +I+                          E+    + + QS
Sbjct: 1040 NKELEEMTDIADNSEELKEKIDSVNEEITKRVANNTTIDELIRH--LHEDLKNAEAKLQS 1097

Query: 1367 ILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTIT 1426
            I ++++    L+KS               ++   ++  L  + E K  E+          
Sbjct: 1098 IPHVDDNTDSLQKSLDEVLAQISQKQRENDELNDEISRLIQEKEEKTDEL-NNMETIPDK 1156

Query: 1427 LTQRNDEFENVRQQLVEYEKRIEDLTYEKE---SELAILR---LKMHENANHYETMQKES 1480
              + + E E V+ Q+ E +K  E +  E +    EL  LR    KM  +    E +QK  
Sbjct: 1157 REEISSEIETVKSQIEEKKKNNEKIAEENKKLAEELENLRQTLSKMETSDQPLENIQK-- 1214

Query: 1481 EIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEI 1540
            EIE  K  +E++ K  E   L++   EL +  +E+ +K +E+   +EN + +I   N + 
Sbjct: 1215 EIETTK--QEISEKQKE---LDELKQELEQIKDEDQSKADEISEEIENIKTQIDEKNKKN 1269

Query: 1541 TNLQNMVRASSSKIQKHVSFASDTKQGRDE 1570
              +        S++ + +    D ++ +DE
Sbjct: 1270 EEIAKNNEEKQSELDEKLKELQDLEEIKDE 1299



 Score =  147 bits (355), Expect = 3e-33
 Identities = 242/1223 (19%), Positives = 522/1223 (42%), Gaps = 116/1223 (9%)

Query: 174  DLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWK 233
            ++ +K  E+ Q  E K                      E    ++  +++   + E E+K
Sbjct: 2181 EIDKKEKERQQATEQKQHEIEMYKAKLQHKEQENAVNAEKLHNEIENLKKKIDSQEMEYK 2240

Query: 234  DEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXX 293
            +  + L K ++   V++  +EE N+  +    E+    +++A + +Q             
Sbjct: 2241 NYNESLTKILDKLKVKLEEVEEENRNEDERAEEVENLKAQIASKRKQNDAENEKLSQEIN 2300

Query: 294  XLAKQSIEPSCEEKTEIEEKGSLEIANMTELT-------KKIELLEHLNCQIRQTNKELE 346
             L K+ ++ + +E TEIEE         T+++       +KI+L + ++    +T K  E
Sbjct: 2301 KL-KEELQ-NLQENTEIEEMKQTVEDLKTQISVFGDPEQEKIKLQKEIDELTEKTEKLAE 2358

Query: 347  -----NKLATMGTESKAVSSPSKKGSPLISRKSGRNTA-----SKMKSPWSQLSSETLNQ 396
                 +KL       K V S   +   L   + G         +K+K  + QL  +  + 
Sbjct: 2359 ADDENDKLREQIENLKNVKSRDVEIIDLGEEEDGERQQLVEELNKLKEEYEQL--QNTDD 2416

Query: 397  DTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEH 456
              D K    +++K    I++ NKD   K  ++ E              ++      + E 
Sbjct: 2417 INDLKQEVIDLSKQIDEIKASNKDAQTKSDLLKELSQLNSQIENIIQEEED-----KEEI 2471

Query: 457  QQHMEG-PSLIHVGTNTEDVNEIAKVQEQL--KQELNDEIKDVNVKDLIEKLKSAEEQIT 513
            + H+E   SL+    + ED  E+  +++QL  KQ L +++K+ ++K   E+ + A++ I 
Sbjct: 2472 RSHIEEIKSLLDNKQSEEDEKELDDLKKQLEDKQSLINKLKE-DIKLTKEENEKAQKNID 2530

Query: 514  QLNDEIDAANKNM---IKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIV-RLTEELHHLSQ 569
             L  E D  N       +     KL   ++++     S+    NKE   +L +E++ L++
Sbjct: 2531 DLEQEFDDLNNEYEEESQFDEERKLLETEIERLKQLISEKKTQNKEKTDKLFKEINDLTE 2590

Query: 570  KVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQ- 628
            ++  LE++  N +L     +    I S   K+    +   E   K +  L ++   +++ 
Sbjct: 2591 ELNSLEDDSENKELQSQIDELNEQINS--VKEESNPQQTKENLQKELDDLNNKLQQMIED 2648

Query: 629  --ELHILQQKYDEVEDKLADI-SQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENL 685
              E   L+++ D ++++L D  SQ ++ Q+ S+I    L+EQI      + E++    +L
Sbjct: 2649 EEENEKLKEEIDALKEELKDNKSQEENQQLKSQISE--LQEQI---KQKQNEISETENSL 2703

Query: 686  KLDKEQLYGTIKDLENDKEDIMNKLQNYI---QENMDLTDKLEKMSAEKISELLAKINH- 741
            K    QL   +K+ E+++ D  N L   I   +E ++  +   K  + ++S+LL  +   
Sbjct: 2704 KSQISQLQNELKEKESERGDKSNSLYKEIDSLKEKINNQEIENKADSSQLSDLLKDLKKK 2763

Query: 742  -----EEQSKIQTQFGID--------AKIQER----DLYIENIESELSK--YKSRICRLE 782
                 EE   I+++   +        AK++E     +  +EN+  +  K   +  +  L+
Sbjct: 2764 LQELTEENETIKSKISEEKEKSKSEMAKLEEEKKSLNKELENVNDDEDKEMLEGEVSSLK 2823

Query: 783  ESI----AVMEDRRYSLERKADQLG---SYLQEKQKAYSEYTIQEDEL--VNRLAVLMDH 833
            E++     + E+++  L ++ ++L    S L + +    E   +++EL  +   + L+  
Sbjct: 2824 ETLNLKKQINEEQKQKLSQEKEKLTEELSQLNDNEDLKKEIEQKKEELEKLKNDSSLLQE 2883

Query: 834  DRVVEKQLLE-IEHENKELQK-----KNQILLEENQNLQIS--LSDMQQHYNALVEKANR 885
             + ++KQ+ E  E +N EL K     K +I  +E++N  I+   + ++Q YN LVE+   
Sbjct: 2884 LQDLKKQIEEKSEKQNPELLKQIEDLKKEISEKESENDLITGEKNTVEQQYNKLVEQRKY 2943

Query: 886  TDLAESESTKYQTQLRD------LESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESA 939
             +     + K  + LR       +++N  RI +E +    + KK IE+++ +     +  
Sbjct: 2944 LESTMEAAKKKVSDLRQQCDELSMKNNQFRIDNEKE--FQEIKKSIEEIKGQREQLAKKH 3001

Query: 940  IRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKM---------NLELID 990
              DK+   E      + +T  + +L   K   ENL   + E  K          +LE  +
Sbjct: 3002 NEDKRRAREYNTLARQKLTDAQQKLDAEKAKNENLLKMMSEQEKTVSNLEKESEDLEQKN 3061

Query: 991  KHVQKQQTQSPDYTEQYINEINK-------LNALLKQKDEEIIALNQKINNAQVSYMSMV 1043
            K +++Q T + D+++  I E+ K       LN  L QK ++ I  +  + N +V+  + +
Sbjct: 3062 KELEQQMTSTGDFSQDKIEELRKKKEELQKLNDELSQKQKQNIEQSNSLQNEKVTLSNEI 3121

Query: 1044 SDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFE 1103
               +S       +   ME++++     + +  +  E+L+   +EQ ++  +LK+     +
Sbjct: 3122 ESLKSSTEAMEKESTEMEKKLEEDKGIISEKSKEKEDLEKKSKEQQEKSDKLKQEVAELQ 3181

Query: 1104 MNIPK--TEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQS 1161
                K  TE   ++  I  +    +N +               +  +E  +E   + E+ 
Sbjct: 3182 EKAKKITTENTDLNDKITDLEISISNAERRKKDLEEEIEKSSAKSLQEKEKELEEIAEKK 3241

Query: 1162 AKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTE-NDNLLSTVAEL 1220
             K   E+++ + + I+    +  L   D+ + E+I     K EQ   +  D  ++ +   
Sbjct: 3242 KKEVREMKKQHKQNIRSLESSISLLEQDIKSLEEIQNSSKKSEQEGLQLLDEKVADLKIK 3301

Query: 1221 RSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQ 1280
            +  +   +  R  E+ + W++ L ++  +  +   ++R        K +Q+ + ++   +
Sbjct: 3302 KFELEDIIADRDSELKK-WEKELLEKNKELSEVNRQIRALKG---DKIDQIKEDIKDIDE 3357

Query: 1281 EETNKIVTMEQVTSLQNKLQDKE 1303
            E  +K   +   T   N  +++E
Sbjct: 3358 EIESKKKKLNLNTVEDNDEEEEE 3380



 Score =  120 bits (289), Expect = 3e-25
 Identities = 181/928 (19%), Positives = 421/928 (45%), Gaps = 70/928 (7%)

Query: 217  QMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEE--ANKLLEAARFEISLEHSKL 274
            ++ ++++     + + K++  +L K+I      ++SLE+   NK L++   E++ + + +
Sbjct: 2559 EIERLKQLISEKKTQNKEKTDKLFKEINDLTEELNSLEDDSENKELQSQIDELNEQINSV 2618

Query: 275  AQEL--EQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLE 332
             +E   +Q                +Q IE   E +   EE  +L+     +  K  E  +
Sbjct: 2619 KEESNPQQTKENLQKELDDLNNKLQQMIEDEEENEKLKEEIDALK--EELKDNKSQEENQ 2676

Query: 333  HLNCQIRQTNKELENKLATMG-TESKAVSSPSKKGSPLISRKSGRNTASK-MKSPWSQLS 390
             L  QI +  ++++ K   +  TE+   S  S+  + L  ++S R   S  +      L 
Sbjct: 2677 QLKSQISELQEQIKQKQNEISETENSLKSQISQLQNELKEKESERGDKSNSLYKEIDSLK 2736

Query: 391  SETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIA 450
             +  NQ+ + K + ++++ L   ++ L K L +   +  E +T             + +A
Sbjct: 2737 EKINNQEIENKADSSQLSDL---LKDLKKKLQE---LTEENETIKSKISEEKEKSKSEMA 2790

Query: 451  QLQLEHQQHMEGPSLIHVGTNTEDVN-EIAKVQE--QLKQELNDEIKDVNVKDLIEKLKS 507
            +L+ E +   +    ++   + E +  E++ ++E   LK+++N+E K    + L ++ + 
Sbjct: 2791 KLEEEKKSLNKELENVNDDEDKEMLEGEVSSLKETLNLKKQINEEQK----QKLSQEKEK 2846

Query: 508  AEEQITQLNDEIDAANKNMIKVKSNHKLKLKQ--MQKTIDNFSKVSD-SNKEIVRLTEEL 564
              E+++QLND  D   +   K +   KLK     +Q+  D   ++ + S K+   L +++
Sbjct: 2847 LTEELSQLNDNEDLKKEIEQKKEELEKLKNDSSLLQELQDLKKQIEEKSEKQNPELLKQI 2906

Query: 565  HHLSQKVAELEEEKGNL--QLHLVDYDSGRMIESDVY-KKMIEM--ENLAETRLKA--IS 617
              L ++++E E E   +  + + V+    +++E   Y +  +E   + +++ R +   +S
Sbjct: 2907 EDLKKEISEKESENDLITGEKNTVEQQYNKLVEQRKYLESTMEAAKKKVSDLRQQCDELS 2966

Query: 618  LLESQ-KFDLVQELHILQQKYDEVEDKLADISQLQSDQV--CSEIKSVHLEEQIDALSAS 674
            +  +Q + D  +E   +++  +E++ +   +++  ++      E  ++  ++  DA    
Sbjct: 2967 MKNNQFRIDNEKEFQEIKKSIEEIKGQREQLAKKHNEDKRRAREYNTLARQKLTDAQQKL 3026

Query: 675  KKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISE 734
              E A     LK+  EQ   T+ +LE + ED+  K +   Q+     D     S +KI E
Sbjct: 3027 DAEKAKNENLLKMMSEQ-EKTVSNLEKESEDLEQKNKELEQQMTSTGD----FSQDKIEE 3081

Query: 735  LLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYS 794
            L  K   EE  K+  +     K        +NIE   S    ++  L   I  ++    +
Sbjct: 3082 LRKK--KEELQKLNDELSQKQK--------QNIEQSNSLQNEKVT-LSNEIESLKSSTEA 3130

Query: 795  LERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKK 854
            +E+++ ++   L+E +   SE + ++++L  +     +    +++++ E++ + K++  +
Sbjct: 3131 MEKESTEMEKKLEEDKGIISEKSKEKEDLEKKSKEQQEKSDKLKQEVAELQEKAKKITTE 3190

Query: 855  NQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEH 914
            N  L ++  +L+IS+S+ ++    L E     ++ +S +   Q + ++LE   ++   E 
Sbjct: 3191 NTDLNDKITDLEISISNAERRKKDLEE-----EIEKSSAKSLQEKEKELEEIAEKKKKEV 3245

Query: 915  QTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKN----IEYVTQLEAQLQEYKNN 970
            + +  Q K+ I  LE   +  +E  I+  + +    +K+    ++ + +  A L+  K  
Sbjct: 3246 REMKKQHKQNIRSLESSISL-LEQDIKSLEEIQNSSKKSEQEGLQLLDEKVADLKIKKFE 3304

Query: 971  IENLNMNVE-ELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALN 1029
            +E++  + + EL K   EL++K+ +  +        +  ++I+++   +K  DEEI +  
Sbjct: 3305 LEDIIADRDSELKKWEKELLEKNKELSEVNRQIRALKG-DKIDQIKEDIKDIDEEIESKK 3363

Query: 1030 QKINNAQVSYMSMVSDYESKLAQFTTKLENMEEE--------MQRVSKQLLDSKQHNEEL 1081
            +K+N   V       +  SK   FT  +    E+        +  + KQ  ++K+ N + 
Sbjct: 3364 KKLNLNTVEDNDEEEEESSKPKIFTPTISKPSEQEDNKPKIFVPTIPKQNEENKEENNKP 3423

Query: 1082 QILVREQDDQIKELKETKLTFEMNIPKT 1109
            ++ V     Q +E K+ +   +  +P T
Sbjct: 3424 KVFVPVVPKQTEEQKKEEEKPKFFVPTT 3451



 Score =  102 bits (245), Expect = 7e-20
 Identities = 177/890 (19%), Positives = 365/890 (41%), Gaps = 82/890 (9%)

Query: 722  DKLEKMS-AEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICR 780
            D ++ +S  +K+ E+  ++     + I     +  ++       +   +EL +   R+  
Sbjct: 15   DSIKNISNTKKLQEICLQLYKNRHNLIDVNKQLAQQLARAQQRSQEAYNELKEQSQRMIE 74

Query: 781  LEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQ 840
            LE     +E     L+ K                     E E+  ++  LM       + 
Sbjct: 75   LEHQNESLEYENKELKAKTISFVGEFPNTSGINQADDSNETEI--KIRKLMRTINKQRRD 132

Query: 841  LLEIEHENKELQKKNQILLEENQNLQISLSD----MQQHYNALVEKA----NRTDLAESE 892
            + ++E +NKELQ+           +++  S+    + +  +AL+ K     N     + +
Sbjct: 133  IADLEQKNKELQEA----ATNGPLMKLPASEGGPGLDETKSALLIKQLYRENARSKVQMD 188

Query: 893  STKYQTQLRDLE-SNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYE 951
            S + Q Q +D E  NLK  T    + I +    IE        +   +    +   ++  
Sbjct: 189  SLRKQLQDKDEEIKNLKAATDLSNSRISELSGIIEGESKLSELKTPPSSPSYRNFIDRGN 248

Query: 952  KNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEI 1011
                 + QL+ QL + +  IEN     E LN    E+ID   ++++        Q  +E 
Sbjct: 249  YKDRRMKQLKDQLDQTETEIENEEGKTENLNYSLNEMIDLVAERRRALQELRNSQGKDE- 307

Query: 1012 NKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQL 1071
             KL   + + + E   +  +I + Q      +   + +L + TTK +  E+++  + K +
Sbjct: 308  EKLKKQIAKVESEKTKIEDEIKHLQEDEEPQIKKLKDRLDETTTKTQIAEKKLGEMRKTI 367

Query: 1072 LDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXX 1131
             DS+Q       L + + + I+  KE  LT +     TE   I++ I+ +  + N ++  
Sbjct: 368  EDSRQK------LAQRRQNLIERRKE--LTNDAENTNTELQSINNQIQEIDSEFNKLNGL 419

Query: 1132 XXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQL-ETLNTELTGHDV 1190
                       K   +E+  Q++  L +   K   E      +I ++ + L   +  ++ 
Sbjct: 420  VNKVQSDHSKKKSALQEQLAQKQKDLNDLKRKQAEEKASREAEIAKINDQLQKTMKEYND 479

Query: 1191 VNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADF 1250
            +NQ Q   LK++++Q   +   L S V + R  +    +QR  E+ +L +Q L  +  + 
Sbjct: 480  LNQPQNVDLKNEIDQATKDLKELESRVNKKREELFGKNNQRVAELNKLNEQ-LKSKMDEM 538

Query: 1251 QKTEHELRVQLSAFESKYEQLLDSVQSSTQEETN-----KIVTMEQVTSLQNKLQD---K 1302
             K + EL+      E+K  +L   ++S + E +      +++   +V  L+++L +   +
Sbjct: 539  VKADQELQSAKDEHEAKKNELKAEIESVSDEISKLKDELEVIPDFEVDDLKDQLNELLKE 598

Query: 1303 EEHLRNLQEKYADVINQ-IEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQ 1361
            +E L   + K  D +N  I +L+ EI+ EK A                 D +++ Q   +
Sbjct: 599  KEELEKEKIKNNDELNSSIIMLKDEIQKEK-ANKDKISEEKNKRDKELNDEKSKLQD--E 655

Query: 1362 MQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTH 1421
            +    +  I  EN QL +                ND   K+ +L  Q     S++ QK  
Sbjct: 656  LDSLQLDEIENENDQLFEEVEDLKSKVDDAKILYNDMVDKIDDLKQQR----SKVEQKYK 711

Query: 1422 EYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESE 1481
            +      +++DE E V +++ E +++++                   N N +    K++ 
Sbjct: 712  DLEKQNKEKSDEIEKVSKEISELKEKLD-------------------NLNQF----KDNT 748

Query: 1482 IERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEIT 1541
             E  + ++ +N +I +        ++ N+ ++EE+ K NE    LEN+  EI  +NDE  
Sbjct: 749  PELHQKVDAMNEQIVKK-------SQENEKIQEEMNKLNEELQHLENEMEEIEVVNDERE 801

Query: 1542 NLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDL 1591
             +Q  +     +I++        K+  +E++ + MN  L++A   A+ +L
Sbjct: 802  TIQEKIDNIKQQIEE--------KKKSNEEIQDIMNL-LIEAENDAQKEL 842



 Score = 93.9 bits (223), Expect = 3e-17
 Identities = 191/933 (20%), Positives = 379/933 (40%), Gaps = 77/933 (8%)

Query: 101  KEILMEKIKQYKE----LSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDN 156
            K+++ EK  Q KE    L K  +                    Q+ ++    N++KE+ N
Sbjct: 2564 KQLISEKKTQNKEKTDKLFKEINDLTEELNSLEDDSENKELQSQIDELNEQINSVKEESN 2623

Query: 157  ALSVLQVKMKIMETTILDLQ---------EKINE---------KDQIIEAKNKATTXXXX 198
                 +   K ++     LQ         EK+ E         KD   + +N+       
Sbjct: 2624 PQQTKENLQKELDDLNNKLQQMIEDEEENEKLKEEIDALKEELKDNKSQEENQQLKSQIS 2683

Query: 199  XXXXXXXXXXXXXEDT----KQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLE 254
                          +T    K Q++++Q      E+E  D+   L K+I+S   +I++ E
Sbjct: 2684 ELQEQIKQKQNEISETENSLKSQISQLQNELKEKESERGDKSNSLYKEIDSLKEKINNQE 2743

Query: 255  EANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKG 314
              NK   +   ++  +  K  QEL +               +K  +    EEK  + ++ 
Sbjct: 2744 IENKADSSQLSDLLKDLKKKLQELTEENETIKSKISEEKEKSKSEMAKLEEEKKSLNKE- 2802

Query: 315  SLEIANMTELTKKIE-----LLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPL 369
             LE  N  E  + +E     L E LN + +Q N+E + KL+    +     S       L
Sbjct: 2803 -LENVNDDEDKEMLEGEVSSLKETLNLK-KQINEEQKQKLSQEKEKLTEELSQLNDNEDL 2860

Query: 370  ISR-KSGRNTASKMKSPWSQLSS-ETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYV 427
                +  +    K+K+  S L   + L +  ++K  K     L+  I+ L K++ +KE  
Sbjct: 2861 KKEIEQKKEELEKLKNDSSLLQELQDLKKQIEEKSEKQNPELLKQ-IEDLKKEISEKE-- 2917

Query: 428  ISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQ 487
             SE D             + L+ Q +   +  ME      V    +  +E++    Q + 
Sbjct: 2918 -SENDLITGEKNTVEQQYNKLVEQRKY-LESTMEAAKK-KVSDLRQQCDELSMKNNQFRI 2974

Query: 488  ELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKL-----KLKQMQK 542
            +   E ++  +K  IE++K   EQ+ + ++E D          +  KL     KL   + 
Sbjct: 2975 DNEKEFQE--IKKSIEEIKGQREQLAKKHNE-DKRRAREYNTLARQKLTDAQQKLDAEKA 3031

Query: 543  TIDNFSK-VSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVD-YDSGRMIESDVYK 600
              +N  K +S+  K +  L +E   L QK  ELE++  +      D  +  R  + ++ K
Sbjct: 3032 KNENLLKMMSEQEKTVSNLEKESEDLEQKNKELEQQMTSTGDFSQDKIEELRKKKEELQK 3091

Query: 601  KMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADI-SQLQSDQVCSEI 659
               E+    +  ++  + L+++K  L  E+  L+   + +E +  ++  +L+ D+     
Sbjct: 3092 LNDELSQKQKQNIEQSNSLQNEKVTLSNEIESLKSSTEAMEKESTEMEKKLEEDKGIISE 3151

Query: 660  KSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMD 719
            KS   E+    L    KE     + LK +  +L    K +  +  D+ +K+ + ++ ++ 
Sbjct: 3152 KSKEKED----LEKKSKEQQEKSDKLKQEVAELQEKAKKITTENTDLNDKITD-LEISIS 3206

Query: 720  LTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRIC 779
              ++ +K   E+I +  AK   E++ +++ +     K + R++  ++ +  +   +S I 
Sbjct: 3207 NAERRKKDLEEEIEKSSAKSLQEKEKELE-EIAEKKKKEVREMKKQH-KQNIRSLESSIS 3264

Query: 780  RLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEK 839
             LE+ I  +E+ + S  +K++Q G  L +++ A  +  I++ EL +   ++ D D  ++K
Sbjct: 3265 LLEQDIKSLEEIQNS-SKKSEQEGLQLLDEKVA--DLKIKKFELED---IIADRDSELKK 3318

Query: 840  QLLEIEHENKELQKKN-QILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQT 898
               E+  +NKEL + N QI   +   +     D++     +  K  + +L   E    + 
Sbjct: 3319 WEKELLEKNKELSEVNRQIRALKGDKIDQIKEDIKDIDEEIESKKKKLNLNTVEDNDEEE 3378

Query: 899  QLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVT 958
            +    ES+  +I     T  + K  E ED + +    + +  +  +   E+  K   +V 
Sbjct: 3379 E----ESSKPKIF----TPTISKPSEQEDNKPKI--FVPTIPKQNEENKEENNKPKVFVP 3428

Query: 959  QLEAQLQEYKNNIENLNMNVEELNKMNLELIDK 991
             +  Q +E K   E     V    K N E  D+
Sbjct: 3429 VVPKQTEEQKKEEEKPKFFVPTTPKQNEENKDE 3461


>UniRef50_A2EMR6 Cluster: Viral A-type inclusion protein, putative;
            n=4; cellular organisms|Rep: Viral A-type inclusion
            protein, putative - Trichomonas vaginalis G3
          Length = 2416

 Score =  204 bits (498), Expect = 2e-50
 Identities = 309/1532 (20%), Positives = 663/1532 (43%), Gaps = 142/1532 (9%)

Query: 152  KEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXX 211
            ++ +N   V   K++ +E T   LQE+IN      + K +                    
Sbjct: 653  EDYENYKKVTNEKIQQLENTKRQLQEQINN-----QPKPEGNLAMLQKENEEYQRQINEL 707

Query: 212  EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDI---ESKDVRISSLEEANKLLEAARFEI- 267
            +D K +  K+ E     + ++  E + L   I   E  D  +  L + N  L     E+ 
Sbjct: 708  KDLKTEYLKLIEEKRETDEKYNKEIEELKDRINRGEGGDEVVEELAKENDELSKENEELK 767

Query: 268  -SLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTK 326
              L+  K ++E+E+                +Q  +   E   +IEE   +E     EL K
Sbjct: 768  EKLKDIKSSEEIEELTNQIEELEKELNEKKEQLEQTENELTQQIEE---IEEEKSEELKK 824

Query: 327  KIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPL-----ISRKSGRNTASK 381
            K E +E L  +I + NKE+++    +    + + +  K+   L      S+++ + T  +
Sbjct: 825  KNEEIERLQNEIEELNKEIKSLTEEIDDLQEKLENAKKEIQELQEYAEKSQENDKQTIDE 884

Query: 382  MKSPWSQLSSETLNQDTDKKI-------NKNEIAKLEMVIQSLNKDLVDKEYVISEKDTX 434
            +K    +L++ET   D+D K+        + ++  LE  I  L  ++ D + VI E++  
Sbjct: 885  LKEK-LRLANETKVTDSDTKVLVESKEAAEQKVLLLEKEISDLKIEIEDLKSVIDEENEQ 943

Query: 435  XXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIK 494
                       +  I +L+ E  +  +     +   N E + ++ K  E LK  +++E +
Sbjct: 944  KVSNTEA----ENRIHELESEISELKKELDQNNNQQNDEKIEKLQKEIEDLKSVIDEENE 999

Query: 495  D-VNVKDLIEKLKSAEEQITQLNDEIDAAN--KNMIKVKSNHK----LKLKQMQKTIDNF 547
              V+  +   ++   E +I++L  E+D  N  +N  K++   K    LK +      +N 
Sbjct: 1000 QKVSNTEAENRIHELESEISELKKELDQNNNQQNDEKIEKLQKEIEDLKNELESSKAENE 1059

Query: 548  SKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDV-YKKMIEME 606
               ++  KEI ++++E  +L  ++  L +EKG+ +  ++D  +  + E     + M   E
Sbjct: 1060 ELQNEFEKEIDQISQEKQNLESQIKYL-QEKGD-KSEIIDKLNQTIEELRAKVEHMFTQE 1117

Query: 607  NLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADI-SQLQSDQV-CSEIKSVHL 664
            ++ E +   I  L+ +  ++ +   I ++K  + E+ + ++ ++L++ +   S++KS   
Sbjct: 1118 DIDEYK-SEIENLKQELSNIEKSKQISEEKSQDYEEIVHELENKLEAKETELSKLKS-DF 1175

Query: 665  EEQIDALSASKKELALVIENLKLDKEQLYGT----IKDLENDKEDIMNKLQNYIQENMDL 720
            E+Q   +   K+ +  +   ++++K+         I  LE    D+ NKLQ+ I+   ++
Sbjct: 1176 EQQTREIETLKENITNLENEMEIEKKNRNSADNEKISHLEKQISDLQNKLQDKIKSQNEM 1235

Query: 721  TDKLEKMSAE---KISELLAKINHEEQSKIQTQFG-IDAKIQERDLYIENIESELSKYKS 776
             +K ++   E   K  ++  + +H  Q+KI++    +    +E D    N E +L+K   
Sbjct: 1236 VEKFKRDFQEMQAKDQKIREEESHASQAKIESLNALLKQSKEENDALKMNHEIKLNKISE 1295

Query: 777  RICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRV 836
                LE+ +   E     L ++       + +  K  SE     DE       L   + V
Sbjct: 1296 FTKDLEQKVKSKEQEIELLTQQNSVCSKEINDLHKNNSELKKLSDE-------LQSENNV 1348

Query: 837  VEKQLLEIEHENKELQKKNQILLEENQ--NLQISLSDMQQHYNALVEKANRTDLAESEST 894
            +E++L  +  E K LQ +  +   +NQ  NL   +S++ +  N L EK       E + T
Sbjct: 1349 LEEKLKRLMSELKFLQ-ETSVKNTDNQITNLNSKISELSEEINILKEK-------EIKLT 1400

Query: 895  KYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDL---EIEFNTQIESAIRDKKVLNEKYE 951
            K   ++  + S   +I  +++ ++ Q   ++EDL    I  +  +E+  ++      KYE
Sbjct: 1401 K---EIEKVTSEKNKIIQDNEEVVNQLMSDLEDLRRKNINLDELVENLRKEISEEKSKYE 1457

Query: 952  KNI----EYVTQLEAQLQEYKNNIENLNMNVEEL---NKMNLELIDKHV---QKQQTQSP 1001
            ++     E + QL   + E K   E LN+ + +L   N +N E + + +    ++ +++ 
Sbjct: 1458 RDTTKLNETILQLNNTVFEIKKQNEQLNLTISDLSTSNNLNSEKVTQEILELNEKISKAK 1517

Query: 1002 DYTEQYINEINKLNALLKQKDEEIIALNQKIN-------NAQVSYMSMVSDYESKLAQFT 1054
            +  +     I +LN  L+  +EE   L++ I        N+     S+  + E    +  
Sbjct: 1518 EENDNLSRHIEELNQQLESANEENSKLSKTIEEEKTKNLNSSEKSFSLEKEVEKLQEEKE 1577

Query: 1055 TKLENMEEEMQRVS-------------KQLLD-SKQHNEELQILVREQDDQIKELKET-- 1098
              +E  EEE  ++              KQ ++ SK+ NE+L+ ++ E +   +ELK T  
Sbjct: 1578 IFVEKSEEEKNKLKSEVTTLTEISANLKQEIEISKEQNEKLKSMLSEVESNNEELKHTIE 1637

Query: 1099 KLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQE---EEEFIQERS 1155
            +L+ ++N  +T+   +   IE ++      D             + ++   +E F ++ +
Sbjct: 1638 ELSSQINDLQTQNDKVEKQIENLNKTIEEKDETINKMIANSDDSEKRDNEMKELFNKQNN 1697

Query: 1156 VLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVV---NQEQINQLKSKLEQLNTENDN 1212
             + E S  + ++  E    + +++ LN E     V+    +++ + L+ ++++ ++EN  
Sbjct: 1698 KINELSKLIESKTSENDKLLSEIKDLNKENEELAVLVDEKEDENHTLQVRIDEKDSENSQ 1757

Query: 1213 LLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLL 1272
            L + ++++ + ++S  +     I EL K  +  +  +  K    +       E+K  ++ 
Sbjct: 1758 LKTDLSDIENKLNSGKELLNHTIDELTKS-IESKSNENSKLMSAIDQLNKDLENK-NKIT 1815

Query: 1273 DSVQSSTQEETNKIVTMEQVT-----SLQNKLQDKEEHLRNLQEKYADVINQIEILRSEI 1327
            + + +  +E  +K++ + +V       L++ L D E   +   +    +  +IEI   EI
Sbjct: 1816 EEIANKNEENESKLLDLNKVVEELKKQLEHVLIDNESEKQEKSDTEQKLREEIEIKEKEI 1875

Query: 1328 EDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNI-NEENAQLKKSSXXXXX 1386
            +  K                   D   E     +  +  I  I ++   ++ K       
Sbjct: 1876 DKLKKQNDQQIDHFTTQISQINDDHNNEIDQINEDYQTQIDQIKHDHEREMNKLKENHQH 1935

Query: 1387 XXXXXXXRVNDAEAKVLE-----------LTHQLELKDSEIYQKTH-EYTITLTQRNDEF 1434
                    + D E +  E           L  Q+  K+ E  +K + ++T  +++ N+  
Sbjct: 1936 EIESYKQNIEDLEHQFKEIGCKNDEYFNNLIDQINTKNKEEIEKLNVQFTSQISEINENH 1995

Query: 1435 ENVRQQL-VEYEKRIEDLTYEKESELAIL-RLKMHENANHYETMQKESEIERVKLIEELN 1492
            +N  +Q+ ++ ++ I  + Y+  S+++ L  LK  +N   YE  Q  S  E+ K I+ LN
Sbjct: 1996 KNEIEQINIKNQEEIMKINYQFTSQISELNELKEEDNKKIYELCQDNS--EKKKEIDRLN 2053

Query: 1493 VKITESVSLNKQVAELN-KALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASS 1551
             +I E  ++N Q    N K L E+     ++   +++++ EI  LND++T  ++     +
Sbjct: 2054 KEIEEYHNMNHQRENDNEKNLIEKDEIIQKLNKTIKDKQREIDCLNDQLTE-KDESSEEN 2112

Query: 1552 SKIQKHVSFASDTKQGRDEQLDN--TMNKELL 1581
             K+ K +S   ++   +++++ N    N+E+L
Sbjct: 2113 DKLVKFISTLKESLSSKEKEIQNLKKQNEEIL 2144



 Score =  194 bits (473), Expect = 2e-47
 Identities = 286/1348 (21%), Positives = 593/1348 (43%), Gaps = 130/1348 (9%)

Query: 315  SLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKS 374
            S++ A + EL KK E  +    QI   NKEL++ L  +  E  A     +     ++ K+
Sbjct: 563  SIQKARIDELEKKFEQTQ----QIIDENKELKDTLNLLQEEFHAYEMTIQSYETTLNEKN 618

Query: 375  GRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTX 434
              N   + K      S    NQ+TDKK ++NEI   ++     N   V  E +   ++T 
Sbjct: 619  QENDKLRQKLE----SKGIFNQETDKK-DENEIKLKQLNEDYENYKKVTNEKIQQLENTK 673

Query: 435  XXXXXXXXX--GKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDE 492
                         +  +A LQ E++++    + +     TE +  I + +E   ++ N E
Sbjct: 674  RQLQEQINNQPKPEGNLAMLQKENEEYQRQINELK-DLKTEYLKLIEEKRE-TDEKYNKE 731

Query: 493  IKDVNVKDLIEKLKSAEEQITQL---NDEIDAANKNM-IKVKS-NHKLKLKQMQKTIDNF 547
            I++  +KD I + +  +E + +L   NDE+   N+ +  K+K      +++++   I+  
Sbjct: 732  IEE--LKDRINRGEGGDEVVEELAKENDELSKENEELKEKLKDIKSSEEIEELTNQIEEL 789

Query: 548  SKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMEN 607
             K  +  KE +  TE  + L+Q++ E+EEEK   +L   + +  R +++++ +   E+++
Sbjct: 790  EKELNEKKEQLEQTE--NELTQQIEEIEEEKSE-ELKKKNEEIER-LQNEIEELNKEIKS 845

Query: 608  LAETRLKAISLLESQKFDLVQELHILQQK--------YDEVEDKL----------ADISQ 649
            L E        LE+ K + +QEL    +K         DE+++KL          +D   
Sbjct: 846  LTEEIDDLQEKLENAKKE-IQELQEYAEKSQENDKQTIDELKEKLRLANETKVTDSDTKV 904

Query: 650  LQSDQVCSEIKSVHLEEQIDALSASKKELALVIE---NLKLDKEQLYGTIKDLENDKEDI 706
            L   +  +E K + LE++I  L    ++L  VI+     K+   +    I +LE++  ++
Sbjct: 905  LVESKEAAEQKVLLLEKEISDLKIEIEDLKSVIDEENEQKVSNTEAENRIHELESEISEL 964

Query: 707  MNKL-QNYIQENMDLTDKLEK-----------MSAEKISELLAKIN-HEEQSKI-QTQFG 752
              +L QN  Q+N +  +KL+K            + +K+S   A+   HE +S+I + +  
Sbjct: 965  KKELDQNNNQQNDEKIEKLQKEIEDLKSVIDEENEQKVSNTEAENRIHELESEISELKKE 1024

Query: 753  IDA-KIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQ--EK 809
            +D    Q+ D  IE ++ E+   K+    LE S A  E+ +   E++ DQ+    Q  E 
Sbjct: 1025 LDQNNNQQNDEKIEKLQKEIEDLKN---ELESSKAENEELQNEFEKEIDQISQEKQNLES 1081

Query: 810  QKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLL---EIEHENKELQKKNQILLEENQNLQ 866
            Q  Y +    + E++++L   ++  R   + +    +I+    E++   Q L    ++ Q
Sbjct: 1082 QIKYLQEKGDKSEIIDKLNQTIEELRAKVEHMFTQEDIDEYKSEIENLKQELSNIEKSKQ 1141

Query: 867  ISLSDMQQHYNALVEKANRTDLAESESTK----YQTQLRDLESNLKRITHEHQTLIVQKK 922
            IS    Q +   + E  N+ +  E+E +K    ++ Q R++E+  + IT+    + ++KK
Sbjct: 1142 ISEEKSQDYEEIVHELENKLEAKETELSKLKSDFEQQTREIETLKENITNLENEMEIEKK 1201

Query: 923  KEIEDLEIEFNTQIESAIRD-KKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEEL 981
                  + E  + +E  I D +  L +K +   E V + +   QE +   + +       
Sbjct: 1202 NR-NSADNEKISHLEKQISDLQNKLQDKIKSQNEMVEKFKRDFQEMQAKDQKIREEESHA 1260

Query: 982  NKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMS 1041
            ++  +E ++  +++ + ++      +  ++NK++   K  ++++ +  Q+I        S
Sbjct: 1261 SQAKIESLNALLKQSKEENDALKMNHEIKLNKISEFTKDLEQKVKSKEQEI-ELLTQQNS 1319

Query: 1042 MVSDYESKLAQFTTKLENMEEEMQRVSKQLLDS-KQHNEELQIL----VREQDDQIKEL- 1095
            + S   + L +  ++L+ + +E+Q  +  L +  K+   EL+ L    V+  D+QI  L 
Sbjct: 1320 VCSKEINDLHKNNSELKKLSDELQSENNVLEEKLKRLMSELKFLQETSVKNTDNQITNLN 1379

Query: 1096 -KETKLTFEMNIPKTEGMIISSTIEPMSDDANNV---------DXXXXXXXXXXXXLKVQ 1145
             K ++L+ E+NI K + + ++  IE ++ + N +                      + + 
Sbjct: 1380 SKISELSEEINILKEKEIKLTKEIEKVTSEKNKIIQDNEEVVNQLMSDLEDLRRKNINLD 1439

Query: 1146 E-----EEEFIQERSVLQEQSAKLNTELQECYTKIIQL----ETLN---TELTGHDVVNQ 1193
            E      +E  +E+S  +  + KLN  + +    + ++    E LN   ++L+  + +N 
Sbjct: 1440 ELVENLRKEISEEKSKYERDTTKLNETILQLNNTVFEIKKQNEQLNLTISDLSTSNNLNS 1499

Query: 1194 EQINQ----LKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREAD 1249
            E++ Q    L  K+ +   ENDNL   + EL   + SA +    E ++L K    ++  +
Sbjct: 1500 EKVTQEILELNEKISKAKEENDNLSRHIEELNQQLESANE----ENSKLSKTIEEEKTKN 1555

Query: 1250 FQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVT-MEQVTSLQNKLQDKEEHLRN 1308
               +E    ++      K ++  +     ++EE NK+ + +  +T +   L+ + E  + 
Sbjct: 1556 LNSSEKSFSLEKEV--EKLQEEKEIFVEKSEEEKNKLKSEVTTLTEISANLKQEIEISKE 1613

Query: 1309 LQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSIL 1368
              EK   +++++E    E++                      DL+T+N   ++  E    
Sbjct: 1614 QNEKLKSMLSEVESNNEELK-----------HTIEELSSQINDLQTQNDKVEKQIENLNK 1662

Query: 1369 NINEENAQLKK---SSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTI 1425
             I E++  + K   +S              N    K+ EL+  +E K SE  +   E   
Sbjct: 1663 TIEEKDETINKMIANSDDSEKRDNEMKELFNKQNNKINELSKLIESKTSENDKLLSEIK- 1721

Query: 1426 TLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERV 1485
             L + N+E   +  +  +    ++    EK+SE + L+  + +  N   + ++       
Sbjct: 1722 DLNKENEELAVLVDEKEDENHTLQVRIDEKDSENSQLKTDLSDIENKLNSGKELLNHTID 1781

Query: 1486 KLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQN 1545
            +L + +  K  E+  L   + +LNK LE +   T E+    E  E +++ LN  +  L+ 
Sbjct: 1782 ELTKSIESKSNENSKLMSAIDQLNKDLENKNKITEEIANKNEENESKLLDLNKVVEELKK 1841

Query: 1546 MVRASSSKIQKHVSFASDTKQGRDEQLD 1573
             +       +      SDT+Q   E+++
Sbjct: 1842 QLEHVLIDNESEKQEKSDTEQKLREEIE 1869



 Score =  172 bits (418), Expect = 8e-41
 Identities = 295/1473 (20%), Positives = 628/1473 (42%), Gaps = 129/1473 (8%)

Query: 212  EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIES-KDVRISSLEEANKLLEAARFEI--- 267
            E+   Q+ ++++     + + +  +  L + IE  ++ +   L++ N+ +E  + EI   
Sbjct: 780  EELTNQIEELEKELNEKKEQLEQTENELTQQIEEIEEEKSEELKKKNEEIERLQNEIEEL 839

Query: 268  SLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEE-KGSLEIANMTELTK 326
            + E   L +E++               L + + +    +K  I+E K  L +AN T++T 
Sbjct: 840  NKEIKSLTEEIDDLQEKLENAKKEIQELQEYAEKSQENDKQTIDELKEKLRLANETKVTD 899

Query: 327  K-IELLEHLNCQIRQTNKELENKLATMGTESKAVSSP-SKKGSPLISRKSGRNTASKMKS 384
               ++L        Q    LE +++ +  E + + S   ++    +S     N   +++S
Sbjct: 900  SDTKVLVESKEAAEQKVLLLEKEISDLKIEIEDLKSVIDEENEQKVSNTEAENRIHELES 959

Query: 385  PWSQLSSE---TLNQDTDKKINK--NEIAKLEMVIQSLNKDLV---DKEYVISEKDTXXX 436
              S+L  E     NQ  D+KI K   EI  L+ VI   N+  V   + E  I E ++   
Sbjct: 960  EISELKKELDQNNNQQNDEKIEKLQKEIEDLKSVIDEENEQKVSNTEAENRIHELESEIS 1019

Query: 437  XXXXXXXGK-----DTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELND 491
                          D  I +LQ E +  ++         N E  NE  K  +Q+ QE  +
Sbjct: 1020 ELKKELDQNNNQQNDEKIEKLQKEIED-LKNELESSKAENEELQNEFEKEIDQISQEKQN 1078

Query: 492  EIKDVNVKDLIEKLKSAE--EQITQLNDEIDAANKNMIKVKS--NHKLKLKQMQKTIDNF 547
               +  +K L EK   +E  +++ Q  +E+ A  ++M   +    +K +++ +++ + N 
Sbjct: 1079 --LESQIKYLQEKGDKSEIIDKLNQTIEELRAKVEHMFTQEDIDEYKSEIENLKQELSNI 1136

Query: 548  SKVSDSNKEIVRLTEELHH-----LSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKM 602
             K    ++E  +  EE+ H     L  K  EL + K + +    + ++ +   +++  +M
Sbjct: 1137 EKSKQISEEKSQDYEEIVHELENKLEAKETELSKLKSDFEQQTREIETLKENITNLENEM 1196

Query: 603  -IEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLA-DISQLQS-DQVCSEI 659
             IE +N      + IS LE Q  DL  +L    +  +E+ +K   D  ++Q+ DQ   E 
Sbjct: 1197 EIEKKNRNSADNEKISHLEKQISDLQNKLQDKIKSQNEMVEKFKRDFQEMQAKDQKIREE 1256

Query: 660  KSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTI----KDLENDKEDIMNKLQNYIQ 715
            +S   + +I++L+A  K+     + LK++ E     I    KDLE   +    +++   Q
Sbjct: 1257 ESHASQAKIESLNALLKQSKEENDALKMNHEIKLNKISEFTKDLEQKVKSKEQEIELLTQ 1316

Query: 716  ENMDLTDK---LEKMSAE--KISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESE 770
            +N   + +   L K ++E  K+S+ L   N+  + K++        +QE    ++N +++
Sbjct: 1317 QNSVCSKEINDLHKNNSELKKLSDELQSENNVLEEKLKRLMSELKFLQETS--VKNTDNQ 1374

Query: 771  LSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVL 830
            ++   S+I  L E I +++++   L ++ +++ S   EK K   +     ++L++ L  L
Sbjct: 1375 ITNLNSKISELSEEINILKEKEIKLTKEIEKVTS---EKNKIIQDNEEVVNQLMSDLEDL 1431

Query: 831  ----MDHDRVVEKQLLEIEHENKELQ----KKNQILLE----------ENQNLQISLSDM 872
                ++ D +VE    EI  E  + +    K N+ +L+          +N+ L +++SD+
Sbjct: 1432 RRKNINLDELVENLRKEISEEKSKYERDTTKLNETILQLNNTVFEIKKQNEQLNLTISDL 1491

Query: 873  QQHYNALVEKANRTDL--------AESESTKYQTQLRDLESNLKRITHEH----QTLIVQ 920
                N   EK  +  L        A+ E+      + +L   L+    E+    +T+  +
Sbjct: 1492 STSNNLNSEKVTQEILELNEKISKAKEENDNLSRHIEELNQQLESANEENSKLSKTIEEE 1551

Query: 921  KKKEIEDLEIEFNTQ--IESAIRDKKVLNEKYE--KN-----IEYVTQLEAQLQEY---- 967
            K K +   E  F+ +  +E    +K++  EK E  KN     +  +T++ A L++     
Sbjct: 1552 KTKNLNSSEKSFSLEKEVEKLQEEKEIFVEKSEEEKNKLKSEVTTLTEISANLKQEIEIS 1611

Query: 968  KNNIENLNMNVEELNKMNLELIDKH-VQKQQTQSPDYTEQ---YINEINKLNALLKQKDE 1023
            K   E L   + E+   N EL  KH +++  +Q  D   Q      +I  LN  +++KDE
Sbjct: 1612 KEQNEKLKSMLSEVESNNEEL--KHTIEELSSQINDLQTQNDKVEKQIENLNKTIEEKDE 1669

Query: 1024 EI---IALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEE 1080
             I   IA +            + +   +K+ + +  +E+   E  ++  ++ D  + NEE
Sbjct: 1670 TINKMIANSDDSEKRDNEMKELFNKQNNKINELSKLIESKTSENDKLLSEIKDLNKENEE 1729

Query: 1081 LQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXX 1140
            L +LV E++D+         T ++ I + +    S     +SD  N ++           
Sbjct: 1730 LAVLVDEKEDE-------NHTLQVRIDEKDSEN-SQLKTDLSDIENKLNSGKELLNHTID 1781

Query: 1141 XLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLK 1200
             L    E +   E S L     +LN +L+       ++   N E     +   + + +LK
Sbjct: 1782 ELTKSIESKS-NENSKLMSAIDQLNKDLENKNKITEEIANKNEENESKLLDLNKVVEELK 1840

Query: 1201 SKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQRE---ADFQKTEHEL 1257
             +LE +  +N++     ++    +   ++ +  EI +L KQ+  Q +       +   + 
Sbjct: 1841 KQLEHVLIDNESEKQEKSDTEQKLREEIEIKEKEIDKLKKQNDQQIDHFTTQISQINDDH 1900

Query: 1258 RVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQ--VTSLQNKLQDKEEHLRNL----QE 1311
              ++      Y+  +D ++   + E NK+    Q  + S +  ++D E   + +     E
Sbjct: 1901 NNEIDQINEDYQTQIDQIKHDHEREMNKLKENHQHEIESYKQNIEDLEHQFKEIGCKNDE 1960

Query: 1312 KYADVINQIEIL-RSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQS-YKQMQEQSILN 1369
             + ++I+QI    + EIE   V F                 +  +NQ    ++  Q    
Sbjct: 1961 YFNNLIDQINTKNKEEIEKLNVQFTSQISEINENHKNEIEQINIKNQEEIMKINYQFTSQ 2020

Query: 1370 INEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQ 1429
            I+E N +LK+                ++ + ++  L  ++E   +  +Q+ ++    L +
Sbjct: 2021 ISELN-ELKEEDNKKIYELCQDN---SEKKKEIDRLNKEIEEYHNMNHQRENDNEKNLIE 2076

Query: 1430 RNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIE 1489
            +++  + + + + + ++ I+ L  ++ +E      +  +      T+ KES   + K I+
Sbjct: 2077 KDEIIQKLNKTIKDKQREIDCLN-DQLTEKDESSEENDKLVKFISTL-KESLSSKEKEIQ 2134

Query: 1490 ELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEI-EIVTLNDEITNLQNMVR 1548
             L  +  E +  N  +  LN+   ++  + NE    +  +EI ++ T N ++ N  +   
Sbjct: 2135 NLKKQNEEILKQNNDLKSLNEQQNDD-KQNNENDIEIMKKEIMKLRTENKDLKNQVSQQH 2193

Query: 1549 ASSSKIQKHVSFASDTKQGRDEQLDNTMNKELL 1581
             +  K+ K +   +  ++   ++L N   + ++
Sbjct: 2194 KALVKLAKSLENKNKAEEKLKQELQNISKQNIV 2226



 Score =  165 bits (401), Expect = 9e-39
 Identities = 303/1471 (20%), Positives = 647/1471 (43%), Gaps = 123/1471 (8%)

Query: 169  ETTILDLQEKINE-KDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIA 227
            E  I +L+ +I+E K ++ +  N+                    E +K +  ++Q  F  
Sbjct: 1008 ENRIHELESEISELKKELDQNNNQQNDEKIEKLQKEIEDLKNELESSKAENEELQNEFEK 1067

Query: 228  MEAEWKDEKQRL---LKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXX 284
               +   EKQ L   +K ++ K  +   +++ N+ +E  R ++  EH    +++++    
Sbjct: 1068 EIDQISQEKQNLESQIKYLQEKGDKSEIIDKLNQTIEELRAKV--EHMFTQEDIDEYKSE 1125

Query: 285  XXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKE 344
                      + K   +   EEK++  E+   E+ N  E  K+ EL + L     Q  +E
Sbjct: 1126 IENLKQELSNIEKS--KQISEEKSQDYEEIVHELENKLE-AKETELSK-LKSDFEQQTRE 1181

Query: 345  LENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMK-SPWSQLSSETLNQDTDKKIN 403
            +E       T  + +++   +   +   K  RN+A   K S   +  S+  N+  DK  +
Sbjct: 1182 IE-------TLKENITNLENE---MEIEKKNRNSADNEKISHLEKQISDLQNKLQDKIKS 1231

Query: 404  KNE-IAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQ--QHM 460
            +NE + K +   Q +      K+  I E+++            + L+ Q + E+   +  
Sbjct: 1232 QNEMVEKFKRDFQEMQA----KDQKIREEESHASQAKIESL--NALLKQSKEENDALKMN 1285

Query: 461  EGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEID 520
                L  +   T+D+ +  K +EQ + EL  +   V  K+ I  L     ++ +L+DE+ 
Sbjct: 1286 HEIKLNKISEFTKDLEQKVKSKEQ-EIELLTQQNSVCSKE-INDLHKNNSELKKLSDELQ 1343

Query: 521  AANKNMIKVKSNHKL-KLKQMQKT-IDNF-SKVSDSNKEIVRLTEELHHLSQKVAELEEE 577
            + N N+++ K    + +LK +Q+T + N  +++++ N +I  L+EE++ L +K  +L +E
Sbjct: 1344 SEN-NVLEEKLKRLMSELKFLQETSVKNTDNQITNLNSKISELSEEINILKEKEIKLTKE 1402

Query: 578  KGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKY 637
                 +  V  +  ++I+ +       M +L + R K I+L E  + +L +E+   + KY
Sbjct: 1403 -----IEKVTSEKNKIIQDNEEVVNQLMSDLEDLRRKNINLDELVE-NLRKEISEEKSKY 1456

Query: 638  DEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKE--QLYGT 695
            +    KL + + LQ +    EIK  +  EQ++ L+ S    +  + + K+ +E  +L   
Sbjct: 1457 ERDTTKLNE-TILQLNNTVFEIKKQN--EQLN-LTISDLSTSNNLNSEKVTQEILELNEK 1512

Query: 696  IKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDA 755
            I   + + +++   ++   Q+     ++  K+S     E    +N  E+S    +  ++ 
Sbjct: 1513 ISKAKEENDNLSRHIEELNQQLESANEENSKLSKTIEEEKTKNLNSSEKS-FSLEKEVEK 1571

Query: 756  KIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSE 815
              +E+++++E  E E +K KS +  L E  A ++      + + ++L S L E +    E
Sbjct: 1572 LQEEKEIFVEKSEEEKNKLKSEVTTLTEISANLKQEIEISKEQNEKLKSMLSEVESNNEE 1631

Query: 816  YTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQI---LLEENQNLQISLSDM 872
                 +EL +++  L   +  VEKQ   IE+ NK +++K++    ++  + + +   ++M
Sbjct: 1632 LKHTIEELSSQINDLQTQNDKVEKQ---IENLNKTIEEKDETINKMIANSDDSEKRDNEM 1688

Query: 873  QQHYNALVEKANR-TDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIE 931
            ++ +N    K N  + L ES++++    L +++ +L +   E   L+ +K+ E   L++ 
Sbjct: 1689 KELFNKQNNKINELSKLIESKTSENDKLLSEIK-DLNKENEELAVLVDEKEDENHTLQVR 1747

Query: 932  F------NTQIESAIRD-KKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKM 984
                   N+Q+++ + D +  LN   E     + +L   ++   N    L   +++LNK 
Sbjct: 1748 IDEKDSENSQLKTDLSDIENKLNSGKELLNHTIDELTKSIESKSNENSKLMSAIDQLNK- 1806

Query: 985  NLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVS 1044
            +LE  +K + ++     +  E  + ++NK+   LK++ E ++  N+       S     S
Sbjct: 1807 DLENKNK-ITEEIANKNEENESKLLDLNKVVEELKKQLEHVLIDNE-------SEKQEKS 1858

Query: 1045 DYESKLAQFTTKLENMEEEMQRVSKQLLDSKQH-NEELQILVREQDDQIKELKETKLTFE 1103
            D E KL +   ++E  E+E+ ++ KQ      H   ++  +  + +++I ++ E   T  
Sbjct: 1859 DTEQKLRE---EIEIKEKEIDKLKKQNDQQIDHFTTQISQINDDHNNEIDQINEDYQTQI 1915

Query: 1104 MNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEF----IQERSVLQE 1159
              I       ++   E    +  +              +  + +E F     Q  +  +E
Sbjct: 1916 DQIKHDHEREMNKLKENHQHEIESYKQNIEDLEHQFKEIGCKNDEYFNNLIDQINTKNKE 1975

Query: 1160 QSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLK-------SKLEQLNTENDN 1212
            +  KLN +     ++I   E    E+   ++ NQE+I ++        S+L +L  E++ 
Sbjct: 1976 EIEKLNVQFTSQISEI--NENHKNEIEQINIKNQEEIMKINYQFTSQISELNELKEEDNK 2033

Query: 1213 LLSTVAELRSSISSAVDQRGFEIAELW----------KQHLAQREADFQKTEHELRVQLS 1262
             +  + +  S     +D+   EI E            +++L +++   QK    ++ +  
Sbjct: 2034 KIYELCQDNSEKKKEIDRLNKEIEEYHNMNHQRENDNEKNLIEKDEIIQKLNKTIKDKQR 2093

Query: 1263 AFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEI 1322
              +   +QL +  +SS  EE +K+V    +++L+  L  KE+ ++NL+++  +++ Q   
Sbjct: 2094 EIDCLNDQLTEKDESS--EENDKLVKF--ISTLKESLSSKEKEIQNLKKQNEEILKQNND 2149

Query: 1323 LRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQM--QEQSILNINEENAQLKKS 1380
            L+S + +++                    LRTEN+  K    Q+   L    ++ + K  
Sbjct: 2150 LKS-LNEQQNDDKQNNENDIEIMKKEIMKLRTENKDLKNQVSQQHKALVKLAKSLENKNK 2208

Query: 1381 SXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQR---NDEFENV 1437
            +            + N  + +  +LT  ++ KD+++ +   E T  L +         + 
Sbjct: 2209 AEEKLKQELQNISKQNIVKNEEDKLTLLVKDKDNQLQRCRKELTNALQKAALYRAGLRSS 2268

Query: 1438 RQQLVEYEKRIEDLTYEKESE------LAILRLKMHENANHYETMQKESEIERVKLIEEL 1491
            ++Q++E +K IED      SE         LR +    A   ET  ++ EIE V+L  EL
Sbjct: 2269 QKQIIEIKKEIEDFKSSVSSEDILHERCLFLRARPALLAALTETETQKGEIEAVEL--EL 2326

Query: 1492 NVKITESVSLNKQVAELNKALEEEVAKTNEM--QTALENQEIEIVTLNDEITNLQNMVRA 1549
            N          K   +L+  +  E+ KT ++  +TA+  +E ++   +     ++  V+ 
Sbjct: 2327 NDTKDSLAKALKDNRDLSSHI-VEMRKTIKLLKKTAITLEE-KVKEKDSGREQIEEKVKE 2384

Query: 1550 SSSKIQKHVSFASDTKQGRDEQLDNTMNKEL 1580
               K    +    +  Q R++ L N M K+L
Sbjct: 2385 LEKKNSSALRLIGELWQ-RNQTLINAMPKDL 2414



 Score =  163 bits (395), Expect = 5e-38
 Identities = 252/1242 (20%), Positives = 543/1242 (43%), Gaps = 121/1242 (9%)

Query: 392  ETLNQDTDKKINKNEIAKLEMV-IQSLNKDLVDKEYVISE----KDTXXX------XXXX 440
            + L  DT+ ++N + +  ++   I  L K     + +I E    KDT             
Sbjct: 546  DNLLNDTEIQVNDSALVSIQKARIDELEKKFEQTQQIIDENKELKDTLNLLQEEFHAYEM 605

Query: 441  XXXGKDTLIAQLQLEH---QQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVN 497
                 +T + +   E+   +Q +E   + +  T+ +D NEI     +LKQ LN++ ++  
Sbjct: 606  TIQSYETTLNEKNQENDKLRQKLESKGIFNQETDKKDENEI-----KLKQ-LNEDYENYK 659

Query: 498  VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEI 557
             K   EK++  E    QL ++I+    N  K + N  +  K+ ++     +++ D   E 
Sbjct: 660  -KVTNEKIQQLENTKRQLQEQIN----NQPKPEGNLAMLQKENEEYQRQINELKDLKTEY 714

Query: 558  VRLTEELHHLSQKV-AELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAI 616
            ++L EE     +K   E+EE K  +       + G  +  ++ K+  E+    E   + +
Sbjct: 715  LKLIEEKRETDEKYNKEIEELKDRINRG----EGGDEVVEELAKENDELSKENEELKEKL 770

Query: 617  SLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKK 676
              ++S + ++ +  + +++   E+ +K   + Q +++ +  +I+ +  EE+ + L    +
Sbjct: 771  KDIKSSE-EIEELTNQIEELEKELNEKKEQLEQTENE-LTQQIEEIE-EEKSEELKKKNE 827

Query: 677  ELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQN---YIQENMDLTDKLEKMSAEKIS 733
            E    IE L+ + E+L   IK L  + +D+  KL+N    IQE  +  +K ++   + I 
Sbjct: 828  E----IERLQNEIEELNKEIKSLTEEIDDLQEKLENAKKEIQELQEYAEKSQENDKQTID 883

Query: 734  ELLAKINHEEQSKI---QTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMED 790
            EL  K+    ++K+    T+  +++K +  +  +  +E E+S  K  I  L+  I    +
Sbjct: 884  ELKEKLRLANETKVTDSDTKVLVESK-EAAEQKVLLLEKEISDLKIEIEDLKSVIDEENE 942

Query: 791  RRYS---LERKADQLGSYLQEKQKAYSEYTIQE-DELVNRLAVLMDHDRVVEKQLLEIEH 846
            ++ S    E +  +L S + E +K   +   Q+ DE + +L   ++      K +++ E+
Sbjct: 943  QKVSNTEAENRIHELESEISELKKELDQNNNQQNDEKIEKLQKEIED----LKSVIDEEN 998

Query: 847  ENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESN 906
            E K    + +  + E   L+  +S++++  +      N     + +  K Q ++ DL++ 
Sbjct: 999  EQKVSNTEAENRIHE---LESEISELKKELD-----QNNNQQNDEKIEKLQKEIEDLKNE 1050

Query: 907  LKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIR------DKKVLNEKYEKNIEYVTQ- 959
            L+    E++ L  + +KEI+ +  E    +ES I+      DK  + +K  + IE +   
Sbjct: 1051 LESSKAENEELQNEFEKEIDQISQE-KQNLESQIKYLQEKGDKSEIIDKLNQTIEELRAK 1109

Query: 960  -----LEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQT--QSPDYTEQYINEIN 1012
                  +  + EYK+ IENL   +  + K      +K    ++   +  +  E    E++
Sbjct: 1110 VEHMFTQEDIDEYKSEIENLKQELSNIEKSKQISEEKSQDYEEIVHELENKLEAKETELS 1169

Query: 1013 KLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLL 1072
            KL +  +Q+  EI  L + I N +     M  + +++ +    K+ ++E+++  +  +L 
Sbjct: 1170 KLKSDFEQQTREIETLKENITNLE---NEMEIEKKNRNSADNEKISHLEKQISDLQNKLQ 1226

Query: 1073 DS-KQHNEELQILVRE-QDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDX 1130
            D  K  NE ++   R+ Q+ Q K+ K  +     +  K E +          +DA  ++ 
Sbjct: 1227 DKIKSQNEMVEKFKRDFQEMQAKDQKIREEESHASQAKIESLNALLKQSKEENDALKMNH 1286

Query: 1131 XXXXXXXXXXXLKVQEE-EEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHD 1189
                         ++++ +   QE  +L +Q++  + E+ + +    +L+ L+ EL   +
Sbjct: 1287 EIKLNKISEFTKDLEQKVKSKEQEIELLTQQNSVCSKEINDLHKNNSELKKLSDELQSEN 1346

Query: 1190 VVNQEQINQLKSKLEQL------NTEND--NLLSTVAELRSSISSAVDQRGFEIAELWKQ 1241
             V +E++ +L S+L+ L      NT+N   NL S ++EL   I + + ++  ++ +  ++
Sbjct: 1347 NVLEEKLKRLMSELKFLQETSVKNTDNQITNLNSKISELSEEI-NILKEKEIKLTKEIEK 1405

Query: 1242 HLAQREADFQKTEHELRVQLSAFES------KYEQLLDSVQSSTQEETNKIVTMEQVTSL 1295
              +++    Q  E  +   +S  E         ++L+++++    EE +K    E+ T+ 
Sbjct: 1406 VTSEKNKIIQDNEEVVNQLMSDLEDLRRKNINLDELVENLRKEISEEKSK---YERDTT- 1461

Query: 1296 QNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTE 1355
              KL +    L N   +      Q+ +  S++                         + E
Sbjct: 1462 --KLNETILQLNNTVFEIKKQNEQLNLTISDLSTSNNLNSEKVTQEILELNEKISKAKEE 1519

Query: 1356 NQSYKQMQE---QSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLEL- 1411
            N +  +  E   Q + + NEEN++L K+             +    E +V +L  + E+ 
Sbjct: 1520 NDNLSRHIEELNQQLESANEENSKLSKTIEEEKTKNLNSSEKSFSLEKEVEKLQEEKEIF 1579

Query: 1412 --KDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHEN 1469
              K  E   K      TLT+ +   +   +   E  ++++ +  E ES    L+  + E 
Sbjct: 1580 VEKSEEEKNKLKSEVTTLTEISANLKQEIEISKEQNEKLKSMLSEVESNNEELKHTIEEL 1639

Query: 1470 ANHYETMQKESEIERVKLIEELNVKITE-SVSLNKQVAELNKALEEEVAKTNEMQTALEN 1528
            ++    +Q +++ +  K IE LN  I E   ++NK +A      ++   + NEM+     
Sbjct: 1640 SSQINDLQTQND-KVEKQIENLNKTIEEKDETINKMIAN----SDDSEKRDNEMKELFNK 1694

Query: 1529 QEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDE 1570
            Q       N++I  L  ++ + +S+  K +S   D  +  +E
Sbjct: 1695 Q-------NNKINELSKLIESKTSENDKLLSEIKDLNKENEE 1729



 Score =  151 bits (365), Expect = 2e-34
 Identities = 268/1308 (20%), Positives = 551/1308 (42%), Gaps = 126/1308 (9%)

Query: 87   VPGISESLANTLKQKEILMEKIKQYKEL------SKRSSTTIVRXXXXXXXXXXXXXXXQ 140
            +  + + L+N  K K+I  EK + Y+E+         +  T +                 
Sbjct: 1126 IENLKQELSNIEKSKQISEEKSQDYEEIVHELENKLEAKETELSKLKSDFEQQTREIETL 1185

Query: 141  LGDVTHLSNTIK-EKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXX 199
              ++T+L N ++ EK N  S    K+  +E  I DLQ K+ +K   I+++N+        
Sbjct: 1186 KENITNLENEMEIEKKNRNSADNEKISHLEKQISDLQNKLQDK---IKSQNEMVEKFKRD 1242

Query: 200  XXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSL-EEANK 258
                        E+         E+  A+  + K+E   L  + E K  +IS   ++  +
Sbjct: 1243 FQEMQAKDQKIREEESHASQAKIESLNALLKQSKEENDALKMNHEIKLNKISEFTKDLEQ 1302

Query: 259  LLEAARFEISL---EHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEK-----TEI 310
             +++   EI L   ++S  ++E+                L  QS     EEK     +E+
Sbjct: 1303 KVKSKEQEIELLTQQNSVCSKEINDLHKNNSELKKLSDEL--QSENNVLEEKLKRLMSEL 1360

Query: 311  EEKGSLEIAN----MTELTKKI-ELLEHLNCQIRQTNKELENKLATMGTE-SKAVSSPSK 364
            +      + N    +T L  KI EL E +N  +++   +L  ++  + +E +K +    +
Sbjct: 1361 KFLQETSVKNTDNQITNLNSKISELSEEINI-LKEKEIKLTKEIEKVTSEKNKIIQDNEE 1419

Query: 365  KGSPLIS-----RKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNK 419
              + L+S     R+   N    +++   ++S E    + D       I +L   +  + K
Sbjct: 1420 VVNQLMSDLEDLRRKNINLDELVENLRKEISEEKSKYERDTTKLNETILQLNNTVFEIKK 1479

Query: 420  DLVDKEYVISEKDTXXXXXXXXXXGK----DTLIAQLQLEH---QQHMEGPSLIHVGTNT 472
                    IS+  T           +    +  I++ + E+    +H+E  +      N 
Sbjct: 1480 QNEQLNLTISDLSTSNNLNSEKVTQEILELNEKISKAKEENDNLSRHIEELNQQLESANE 1539

Query: 473  EDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKL--------KSAEEQITQLNDEIDAANK 524
            E+      ++E+  + LN   K  +++  +EKL        + +EE+  +L  E+    +
Sbjct: 1540 ENSKLSKTIEEEKTKNLNSSEKSFSLEKEVEKLQEEKEIFVEKSEEEKNKLKSEVTTLTE 1599

Query: 525  NMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLH 584
                +K   ++  +Q +K     S+V  +N+E+    EE   LS ++ +L+ +   ++  
Sbjct: 1600 ISANLKQEIEISKEQNEKLKSMLSEVESNNEELKHTIEE---LSSQINDLQTQNDKVEKQ 1656

Query: 585  LVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQEL-HILQQKYDEVEDK 643
            + + +     + +   KMI   + +E R   +  L +++ + + EL  +++ K  E +  
Sbjct: 1657 IENLNKTIEEKDETINKMIANSDDSEKRDNEMKELFNKQNNKINELSKLIESKTSENDKL 1716

Query: 644  LADISQLQSDQ----VCSEIK-------SVHLEEQIDALSASKKELALVIENLKLDKEQL 692
            L++I  L  +     V  + K        V ++E+    S  K +L+ +   L   KE L
Sbjct: 1717 LSEIKDLNKENEELAVLVDEKEDENHTLQVRIDEKDSENSQLKTDLSDIENKLNSGKELL 1776

Query: 693  YGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFG 752
              TI +L    E   N+    +     L   LE  +  KI+E +A  N E +SK+     
Sbjct: 1777 NHTIDELTKSIESKSNENSKLMSAIDQLNKDLE--NKNKITEEIANKNEENESKLLDLNK 1834

Query: 753  I--DAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKAD-QLGSYLQEK 809
            +  + K Q   + I+N ESE  +      +L E I + E     L+++ D Q+  +  + 
Sbjct: 1835 VVEELKKQLEHVLIDN-ESEKQEKSDTEQKLREEIEIKEKEIDKLKKQNDQQIDHFTTQI 1893

Query: 810  QKAYSEYTIQEDELVNRLAVLMD---HDRVVEKQLLEIEHENKELQKKNQILLEENQNLQ 866
             +   ++  + D++       +D   HD   E   L+  H+++    K  I   E+Q  +
Sbjct: 1894 SQINDDHNNEIDQINEDYQTQIDQIKHDHEREMNKLKENHQHEIESYKQNIEDLEHQFKE 1953

Query: 867  ISLSDMQQHYNALVEKANRTDLAESE--STKYQTQLRDLESNLKRITHEHQTLIVQKKKE 924
            I   +  +++N L+++ N  +  E E  + ++ +Q+ ++  N K   +E + + ++ ++E
Sbjct: 1954 IGCKN-DEYFNNLIDQINTKNKEEIEKLNVQFTSQISEINENHK---NEIEQINIKNQEE 2009

Query: 925  IEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKM 984
            I  +  +F +QI         LNE  E++ + + +L     E K  I+ LN  +EE + M
Sbjct: 2010 IMKINYQFTSQISE-------LNELKEEDNKKIYELCQDNSEKKKEIDRLNKEIEEYHNM 2062

Query: 985  NLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVS 1044
            N      H Q++     +  E+    I KLN  +K K  EI  LN ++     S     S
Sbjct: 2063 N------H-QRENDNEKNLIEK-DEIIQKLNKTIKDKQREIDCLNDQLTEKDES-----S 2109

Query: 1045 DYESKLAQFTT----KLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKL 1100
            +   KL +F +     L + E+E+Q + KQ  +  + N +L+ L  +Q+D  K+  E   
Sbjct: 2110 EENDKLVKFISTLKESLSSKEKEIQNLKKQNEEILKQNNDLKSLNEQQNDD-KQNNEN-- 2166

Query: 1101 TFEMNIPKTEGMIISSTIEPMSDDANN-----VDXXXXXXXXXXXXLKVQEEEEFIQERS 1155
              ++ I K E M + +  + + +  +      V              K+++E + I +++
Sbjct: 2167 --DIEIMKKEIMKLRTENKDLKNQVSQQHKALVKLAKSLENKNKAEEKLKQELQNISKQN 2224

Query: 1156 VLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLS 1215
            +++ +  KL   +++   K  QL+    ELT       ++    ++ L     +   +  
Sbjct: 2225 IVKNEEDKLTLLVKD---KDNQLQRCRKELTN----ALQKAALYRAGLRSSQKQIIEIKK 2277

Query: 1216 TVAELRSSISS--AVDQRGFEIAELWKQHLAQREADFQKTEHE-LRVQLSAFESKYEQLL 1272
             + + +SS+SS   + +R   +        A  E + QK E E + ++L+  +    + L
Sbjct: 2278 EIEDFKSSVSSEDILHERCLFLRARPALLAALTETETQKGEIEAVELELNDTKDSLAKAL 2337

Query: 1273 DSVQ--SSTQEETNKIVTMEQVT--SLQNKLQDKEEHLRNLQEKYADV 1316
               +  SS   E  K + + + T  +L+ K+++K+     ++EK  ++
Sbjct: 2338 KDNRDLSSHIVEMRKTIKLLKKTAITLEEKVKEKDSGREQIEEKVKEL 2385



 Score =  145 bits (352), Expect = 8e-33
 Identities = 205/925 (22%), Positives = 410/925 (44%), Gaps = 100/925 (10%)

Query: 695  TIKDLENDK-EDIMNKLQNYIQENMD--LTD-KLEKMSAEKISELLAKINHEEQSKIQTQ 750
            TI D E       + K+   + EN D  L D +++   +  +S   A+I+  E+   QTQ
Sbjct: 521  TIIDSEESTWNKFVQKIMFILDENFDNLLNDTEIQVNDSALVSIQKARIDELEKKFEQTQ 580

Query: 751  FGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQ 810
              ID   + +D  +  ++ E   Y+  I   E ++         L +K +  G + QE  
Sbjct: 581  QIIDENKELKDT-LNLLQEEFHAYEMTIQSYETTLNEKNQENDKLRQKLESKGIFNQETD 639

Query: 811  KAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKK--NQ--------ILLE 860
            K   E  I+  +L        ++ +V  +++ ++E+  ++LQ++  NQ        +L +
Sbjct: 640  KK-DENEIKLKQLNEDYE---NYKKVTNEKIQQLENTKRQLQEQINNQPKPEGNLAMLQK 695

Query: 861  ENQNLQIS---LSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTL 917
            EN+  Q     L D++  Y  L+E+   TD       KY  ++ +L+  + R       +
Sbjct: 696  ENEEYQRQINELKDLKTEYLKLIEEKRETD------EKYNKEIEELKDRINR-GEGGDEV 748

Query: 918  IVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMN 977
            + +  KE ++L  E N +++  ++D K  +E+ E+    + +LE +L E K   E L   
Sbjct: 749  VEELAKENDELSKE-NEELKEKLKDIKS-SEEIEELTNQIEELEKELNEKK---EQLEQT 803

Query: 978  VEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQV 1037
              EL +  +E I++   ++  +  +  E+  NEI +LN  +K   EEI  L +K+ NA+ 
Sbjct: 804  ENELTQQ-IEEIEEEKSEELKKKNEEIERLQNEIEELNKEIKSLTEEIDDLQEKLENAKK 862

Query: 1038 SYMSMVSDYESKLAQFTTKLENMEEEMQRV---------SKQLLDSKQHNEELQILVREQ 1088
                +    E         ++ ++E+++           +K L++SK+  E+  +L+ ++
Sbjct: 863  EIQELQEYAEKSQENDKQTIDELKEKLRLANETKVTDSDTKVLVESKEAAEQKVLLLEKE 922

Query: 1089 DDQIK-ELKETKLTF-EMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQE 1146
               +K E+++ K    E N  K       + I  +  + + +              K+++
Sbjct: 923  ISDLKIEIEDLKSVIDEENEQKVSNTEAENRIHELESEISELKKELDQNNNQQNDEKIEK 982

Query: 1147 EEEFIQE-RSVLQEQSAK--LNTELQECYTKI-IQLETLNTEL-TGHDVVNQEQINQLKS 1201
             ++ I++ +SV+ E++ +   NTE +    ++  ++  L  EL   ++  N E+I +L+ 
Sbjct: 983  LQKEIEDLKSVIDEENEQKVSNTEAENRIHELESEISELKKELDQNNNQQNDEKIEKLQK 1042

Query: 1202 KLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQ-HLAQREAD-------FQKT 1253
            ++E L  E ++  +   EL++     +DQ   E   L  Q    Q + D         +T
Sbjct: 1043 EIEDLKNELESSKAENEELQNEFEKEIDQISQEKQNLESQIKYLQEKGDKSEIIDKLNQT 1102

Query: 1254 EHELRVQ---------LSAFESKYEQL---LDSVQSSTQEETNKIVTMEQVT-SLQNKLQ 1300
              ELR +         +  ++S+ E L   L +++ S Q    K    E++   L+NKL+
Sbjct: 1103 IEELRAKVEHMFTQEDIDEYKSEIENLKQELSNIEKSKQISEEKSQDYEEIVHELENKLE 1162

Query: 1301 DKEEHLRNLQEKYADVINQIEILR-------SEIEDEKVAFXXXXXXXXXXXXXXXXDLR 1353
             KE  L  L+  +     +IE L+       +E+E EK                   DL+
Sbjct: 1163 AKETELSKLKSDFEQQTREIETLKENITNLENEMEIEKKNRNSADNEKISHLEKQISDLQ 1222

Query: 1354 TENQ----SYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVN------DAEAKVL 1403
             + Q    S  +M E+   +  E  A+ +K               +N        E   L
Sbjct: 1223 NKLQDKIKSQNEMVEKFKRDFQEMQAKDQKIREEESHASQAKIESLNALLKQSKEENDAL 1282

Query: 1404 ELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILR 1463
            ++ H+++L  ++I + T +    +  +  E E + QQ     K I DL ++  SEL  L 
Sbjct: 1283 KMNHEIKL--NKISEFTKDLEQKVKSKEQEIELLTQQNSVCSKEINDL-HKNNSELKKLS 1339

Query: 1464 LKMHENANHYETMQKESEIERVKLIEELNVKITES--VSLNKQVAELNKAL----EEEVA 1517
             ++    N  E   K   +  +K ++E +VK T++   +LN +++EL++ +    E+E+ 
Sbjct: 1340 DELQSENNVLEEKLKRL-MSELKFLQETSVKNTDNQITNLNSKISELSEEINILKEKEIK 1398

Query: 1518 KTNEMQTALENQEIEIVTLNDEITN 1542
             T E++  + +++ +I+  N+E+ N
Sbjct: 1399 LTKEIE-KVTSEKNKIIQDNEEVVN 1422



 Score = 59.7 bits (138), Expect = 7e-07
 Identities = 86/384 (22%), Positives = 160/384 (41%), Gaps = 33/384 (8%)

Query: 1197 NQLKSKLEQLNTEN-DNLLSTVAELRSSISSAVDQRGFEIAELWK-----QHLAQREADF 1250
            N+   K+  +  EN DNLL+   E++ + S+ V  +   I EL K     Q +     + 
Sbjct: 531  NKFVQKIMFILDENFDNLLNDT-EIQVNDSALVSIQKARIDELEKKFEQTQQIIDENKEL 589

Query: 1251 QKTEHELRVQLSAFE---SKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLR 1307
            + T + L+ +  A+E     YE  L+       +   K+ +        +K  + E  L+
Sbjct: 590  KDTLNLLQEEFHAYEMTIQSYETTLNEKNQENDKLRQKLESKGIFNQETDKKDENEIKLK 649

Query: 1308 NLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSI 1367
             L E Y +          ++E+ K                    L+ EN+ Y Q Q   +
Sbjct: 650  QLNEDYENYKKVTNEKIQQLENTKRQLQEQINNQPKPEGNLAM-LQKENEEY-QRQINEL 707

Query: 1368 LNINEENAQL----KKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEY 1423
             ++  E  +L    +++             R+N  E    E+  +L  ++ E+ ++  E 
Sbjct: 708  KDLKTEYLKLIEEKRETDEKYNKEIEELKDRINRGEGGD-EVVEELAKENDELSKENEEL 766

Query: 1424 TITLT--QRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESE 1481
               L   + ++E E +  Q+ E EK + +   +KE      +L+  EN    E  Q+  E
Sbjct: 767  KEKLKDIKSSEEIEELTNQIEELEKELNE---KKE------QLEQTEN----ELTQQIEE 813

Query: 1482 IERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEIT 1541
            IE  K  EEL  K  E   L  ++ ELNK ++    + +++Q  LEN + EI  L +   
Sbjct: 814  IEEEKS-EELKKKNEEIERLQNEIEELNKEIKSLTEEIDDLQEKLENAKKEIQELQEYAE 872

Query: 1542 NLQNMVRASSSKIQKHVSFASDTK 1565
              Q   + +  ++++ +  A++TK
Sbjct: 873  KSQENDKQTIDELKEKLRLANETK 896


>UniRef50_A0CPG2 Cluster: Chromosome undetermined scaffold_23, whole
            genome shotgun sequence; n=2; Paramecium tetraurelia|Rep:
            Chromosome undetermined scaffold_23, whole genome shotgun
            sequence - Paramecium tetraurelia
          Length = 2189

 Score =  200 bits (487), Expect = 3e-49
 Identities = 298/1479 (20%), Positives = 627/1479 (42%), Gaps = 125/1479 (8%)

Query: 151  IKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXX 210
            +KEK+  L + Q+K+K  E  I  L+E+I   + I + + +                   
Sbjct: 612  LKEKNRDLQLYQLKLKDYEENINSLKEEIERLNSIDKQQQENIYKLEQSHKTKEYQLSKY 671

Query: 211  XEDTKQQMTKMQE----------NFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLL 260
             E TK+   K++E           FI    E +++ +    +++     I   +   +  
Sbjct: 672  SEQTKEMTNKVKELNEEKTSEIRKFIIQNEELQEQVRIFEIEVKKLQSNIQGNQRTPERT 731

Query: 261  EAARFEISLEHSKLAQELEQXX--XXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEI 318
               + E+   + KL Q++ +                L +Q I+   E + EI++  + E 
Sbjct: 732  TKLQQELDDLYDKLNQQIGENADLKIQIQNLSTQIKLKEQEIKKLLEIQLEIQQNSNKE- 790

Query: 319  ANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNT 378
                +LTK+I+ L     +  Q+ K+L++++  +    K      KK    + + S ++ 
Sbjct: 791  ---NDLTKEIQELHQQINKYEQSIKQLQDQINKLENLIKYKDQQLKKHE--LQQDSWKDN 845

Query: 379  ASKMKSPWSQLSSETLNQ-DTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXX 437
             SK+++   +L ++ L +     K NK  I KLE  ++S       KE+ I +       
Sbjct: 846  LSKLENQIEELETQQLRELKQQDKQNKETIKKLENQLKS-------KEHEIKKLQDEIKL 898

Query: 438  XXXXXXGKDTLIAQLQLE---HQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIK 494
                    + +I Q+  +    QQ +    L    T  E   EI K++++L  + + EI+
Sbjct: 899  QQEKIQSLEQMIEQINDQFHTSQQQLNEVQLKFQLTIREKDFEINKLKQKLGSQKSPEIQ 958

Query: 495  DVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSN 554
               +  L +++   E +I ++ ++    ++   K++ N++L  K+ Q+TI  + K  +  
Sbjct: 959  S-EIDSLHQQIIEKETEIIKVREDTSELSQ---KIR-NYELDFKKFQETIKEYQKKLERT 1013

Query: 555  KEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLK 614
             ++  L  EL  +  +  +++ +  N  ++  + D+    +    KK+ E +   E   K
Sbjct: 1014 TQLEILISEL-KIKDETNQVKIDDQNSTIN--NQDAIIQSKDQTIKKLQEQQR--EFTKK 1068

Query: 615  AISLLESQK--FDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALS 672
               L+  QK   +  Q+LH   Q     +DK   I+ L+      +++   L++QI  + 
Sbjct: 1069 GDQLINVQKKLIETEQQLHEALQNASISQDK---INTLEQQLALKDLELKKLKDQIKEIQ 1125

Query: 673  ASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKI 732
               + L    ++   +KEQL     + +N  E++ N+++   QEN       +K S E  
Sbjct: 1126 REVERL----QSKLYEKEQLQQKTIEQQNKIEELENQIEKLKQEN-------KKKSQE-- 1172

Query: 733  SELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRR 792
                   N   + K+Q    ++ K +++   IE  +  L   + +I  LEE I + ED +
Sbjct: 1173 -------NQVLEDKVQQLKKLEEKYKKQQNLIEEHKQTLESLERKIKSLEEQIQINEDEK 1225

Query: 793  YSLERKADQLGSYLQEKQKAYSEYTIQE----DELVNRLAVLMDHDRVVEKQLLEIEHEN 848
            YSLER+ D L   L++++K +     Q+    D+++ +L   +     +E Q  E   E 
Sbjct: 1226 YSLEREVDLLKKKLEDERKQFENKINQQARAKDDIIAKLKEKIAELEKLEAQHFEFTQEV 1285

Query: 849  KEL--QKKNQILLE-----ENQNLQISLSDMQQHYNALVEKANRTDLAESESTK-YQTQL 900
            ++L  +KK++  +E     +N   Q  +  ++Q   +L EK      +E ES K    ++
Sbjct: 1286 EDLKEEKKSRKNIESKLQSDNSIYQKQIKQLEQQIKSLQEKLK----SEEESNKILHNEI 1341

Query: 901  RDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQL 960
              +  N+K +  E   LI + +++++ LEI    + E   + K+ ++E+    I  +  +
Sbjct: 1342 EQINVNIK-VKDE---LIYKLQQQVKKLEISIKEKKEQIKQFKQDISER-SSQISQIDLI 1396

Query: 961  EAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQK------QQTQSPDYTEQYINEINKL 1014
            + + +E  + I  L    EE  K  +  +   + K      Q  Q     +Q I+ +  +
Sbjct: 1397 DREKEELNDQI-RLKEKSEESLKQTISTLQSQISKLTKQVQQLIQDKMELQQQIDRLIDI 1455

Query: 1015 NALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDS 1074
               +K K+ EI+ L Q I N        V   +  +   T K++  +E  ++  + + + 
Sbjct: 1456 ENSIKLKEIEILRLVQ-IENDYQRQKEKVKTLDKTITDQTQKIKIYQEYEKQTKESIKNY 1514

Query: 1075 KQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXX 1134
            +Q  +E Q  ++  + +I +LK+    ++  I K     IS   E ++    + +     
Sbjct: 1515 EQELDEKQETIQHLEQEIIKLKQQIDDYQRQITK-----ISKEKETVNQKVKSSETNQQK 1569

Query: 1135 XXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQE 1194
                      ++++E + +   L  +   L ++L+E   +  Q + ++ E       +  
Sbjct: 1570 KIDQLE----EQKQELLNDLQTLNIRVEDLQSQLKELQERRDQFQKIDKEKEDIKRTSDT 1625

Query: 1195 QINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQH--LAQREADFQK 1252
               + K  +++L  E   L + + +   + S  ++Q+  +  +L +Q+  L Q   + Q 
Sbjct: 1626 SERKYKESIKELEKEIQRLKAEMIKKEHNNSKEIEQQIDKAQKLKQQNTQLEQTIKNLQN 1685

Query: 1253 TEHELRV---QLSAFESKYEQLLDSVQSSTQEETNKIVTM-EQVTSLQNKL----QDKEE 1304
             E +L++   Q +    + ++ L+       +   +I  + EQ+  L  KL    +D+E+
Sbjct: 1686 NEKKLKLLEEQCNQISERSQEKLNKKDQIIDDLNKQIKNLNEQINKLNQKLKSVNKDEED 1745

Query: 1305 HLRNLQEKYADVINQIEILRS-EIEDEK-VAFXXXXXXXXXXXXXXXXDLRTENQSYKQM 1362
             + +  E  ADV +  +  +  E E +K                    D   + Q  KQ+
Sbjct: 1746 DIADFGED-ADVDDNNKTKKKYEKESKKDKNEQKTNRQLEKDIEKLTQDNINKTQQIKQL 1804

Query: 1363 QEQSILN---INEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTH-QLELKDSEIYQ 1418
            +EQ   N   I +E  + ++ +            +  + + K  ++   Q E++ +E   
Sbjct: 1805 EEQLKKNQELIQKETIEKQQKTQKEKDENQTIKKQETEIKKKDEQIKKLQEEIQKTEKNS 1864

Query: 1419 KTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHE-NANHYETMQ 1477
            K  +    +     E +   QQ+ + +++I+ L    + +++  + K  + N +  E  +
Sbjct: 1865 KEKDNLEQIKVLKQEIDQKTQQITKLQEQIQKL----QKDISASKQKDEKNNKSEQELKK 1920

Query: 1478 KESEIERVK-LIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTL 1536
            KE EI ++K  IE+ + +  E     K   EL K  +EE+ K  E     ++Q  E   L
Sbjct: 1921 KEEEISKLKEKIEKDSKETNEKKQNEKNQNELIKKQQEEIKKKEEENKKFKDQTNENNKL 1980

Query: 1537 NDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNT 1575
             D+++ L+     +  KI+K      + ++  D+Q   T
Sbjct: 1981 KDQVSKLEKEKSTTDEKIKKQEDKIKELQKQIDDQKQKT 2019



 Score =  174 bits (424), Expect = 1e-41
 Identities = 268/1292 (20%), Positives = 566/1292 (43%), Gaps = 129/1292 (9%)

Query: 397  DTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQ--- 453
            + D  +N+ +   + + +++L   L+  +  I    T           KD LI  LQ   
Sbjct: 238  EKDDHLNQGQNQSVLIEMETLQVQLIQYKIEIEGYKTRMQYIQNELSEKDHLIEDLQNII 297

Query: 454  LEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQIT 513
             +  + ++      +       N          Q  N+  K  N ++  +  K+A +   
Sbjct: 298  KDLTKKIQNRQSNDIQNPISPKNPNKSPSNSFNQNSNNPNK--NQRNPGDATKNAADVFQ 355

Query: 514  QLNDEIDAANKNMIKVKSNHKL---KLKQMQKTIDNFSKVSDSNK-EIVRLTEELHHLSQ 569
            Q  D  D  + N  K K  H L   K K+ + +I ++ K+  + K E  RL +EL+    
Sbjct: 356  QEEDNYDQKDPNEEKKKKKHGLEGAKKKEDEDSIKDYQKIIANLKAENQRLQQELNQAIF 415

Query: 570  KVAELE---EEKGNLQLHLVDYDSGRMIE-SDVYKKMIEMENLAETRLKAISLLESQKFD 625
            K+ + E    EK N QL L++     + +  D   K  ++E   +   K +  +E +  D
Sbjct: 416  KINQQEALINEKDN-QLSLLELREKEIRQLKDQLNKQYKLEQENKQLEKKLGEMEQKIQD 474

Query: 626  LVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENL 685
            L+ E+    + YD+ ++KL +  + QS +     K+  L++Q D L A++K++  + + +
Sbjct: 475  LMLEI----ENYDQ-DNKLNE--KKQSKKEADYQKA--LQKQKDELLANQKKIEQINKQM 525

Query: 686  KLDKEQLYGTIKDLEND---KEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHE 742
            + +       +KDL++    K+  + KLQ  ++E   L   LEK + +  S+ + K++ E
Sbjct: 526  QDEINFFEDQMKDLQDSLRVKDQEVKKLQEQMKE---LNKTLEKSNIQ--SDQIEKLHQE 580

Query: 743  EQSKIQTQFGIDAKIQERDLYIENIESELS--KYKSRICRLEE-SIAVMEDRRYSLERKA 799
              S+ Q    ++ KIQ+++  I+  E E+   K K+R  +L +  +   E+   SL+ + 
Sbjct: 581  AHSQTQLLEELEQKIQQQEYEIKTKEQEIKRLKEKNRDLQLYQLKLKDYEENINSLKEEI 640

Query: 800  DQLGSYLQEKQ------------KAY--SEYTIQEDELVNRLAVLMDHDRV-VEKQLLEI 844
            ++L S  +++Q            K Y  S+Y+ Q  E+ N++  L +     + K +++ 
Sbjct: 641  ERLNSIDKQQQENIYKLEQSHKTKEYQLSKYSEQTKEMTNKVKELNEEKTSEIRKFIIQN 700

Query: 845  EHENKELQ------KKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQ- 897
            E   ++++      KK Q  ++ NQ      + +QQ  + L +K N+  + E+   K Q 
Sbjct: 701  EELQEQVRIFEIEVKKLQSNIQGNQRTPERTTKLQQELDDLYDKLNQ-QIGENADLKIQI 759

Query: 898  ----TQLRDLESNLKRITHEHQTLIVQKK-------KEIEDLEIEFNTQIESAIRDKKVL 946
                TQ++  E  +K++  E Q  I Q         KEI++L  + N + E +I+  +  
Sbjct: 760  QNLSTQIKLKEQEIKKLL-EIQLEIQQNSNKENDLTKEIQELHQQIN-KYEQSIKQLQDQ 817

Query: 947  NEKYEKNIEYVTQL----EAQLQEYKNNIENLNMNVEELNKMNL-ELIDKHVQKQQT--Q 999
              K E  I+Y  Q     E Q   +K+N+  L   +EEL    L EL  +  Q ++T  +
Sbjct: 818  INKLENLIKYKDQQLKKHELQQDSWKDNLSKLENQIEELETQQLRELKQQDKQNKETIKK 877

Query: 1000 SPDYTEQYINEINKLNALLKQKDEEIIALNQKI--------------NNAQVSYMSMV-- 1043
              +  +   +EI KL   +K + E+I +L Q I              N  Q+ +   +  
Sbjct: 878  LENQLKSKEHEIKKLQDEIKLQQEKIQSLEQMIEQINDQFHTSQQQLNEVQLKFQLTIRE 937

Query: 1044 SDYE-SKLAQF--TTKLENMEEEMQRVSKQLLDS-------KQHNEELQILVREQDDQIK 1093
             D+E +KL Q   + K   ++ E+  + +Q+++        ++   EL   +R  +   K
Sbjct: 938  KDFEINKLKQKLGSQKSPEIQSEIDSLHQQIIEKETEIIKVREDTSELSQKIRNYELDFK 997

Query: 1094 ELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQE 1153
            + +ET   ++  + +T  + I  +   + D+ N V               +Q +++ I++
Sbjct: 998  KFQETIKEYQKKLERTTQLEILISELKIKDETNQVKIDDQNSTINNQDAIIQSKDQTIKK 1057

Query: 1154 RSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNL 1213
                Q +  K   +L     K+I+ E    E   +  ++Q++IN L+ +L   + E   L
Sbjct: 1058 LQEQQREFTKKGDQLINVQKKLIETEQQLHEALQNASISQDKINTLEQQLALKDLELKKL 1117

Query: 1214 LSTVAELRSSISSAVDQRGFEIAELWKQHLAQR------EADFQKTEHELR---VQLSAF 1264
               + E++  +   +  + +E  +L ++ + Q+      E   +K + E +    +    
Sbjct: 1118 KDQIKEIQREV-ERLQSKLYEKEQLQQKTIEQQNKIEELENQIEKLKQENKKKSQENQVL 1176

Query: 1265 ESKYEQLLDSVQSSTQEETNKIVTMEQ-VTSLQNKLQDKEEHLR-NLQEKYADVINQIEI 1322
            E K +Q L  ++   +++ N I   +Q + SL+ K++  EE ++ N  EKY+ +  ++++
Sbjct: 1177 EDKVQQ-LKKLEEKYKKQQNLIEEHKQTLESLERKIKSLEEQIQINEDEKYS-LEREVDL 1234

Query: 1323 LRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSX 1382
            L+ ++EDE+  F                 L+ +    ++++ Q      +E   LK+   
Sbjct: 1235 LKKKLEDERKQFENKINQQARAKDDIIAKLKEKIAELEKLEAQH-FEFTQEVEDLKEEKK 1293

Query: 1383 XXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLV 1442
                         +  + ++ +L  Q++    ++  +     I     ++E E +   + 
Sbjct: 1294 SRKNIESKLQSDNSIYQKQIKQLEQQIKSLQEKLKSEEESNKIL----HNEIEQINVNIK 1349

Query: 1443 EYEKRIEDLTYE-KESELAILRLKMHENANHYETMQKESEIERVKLI----EELNVKITE 1497
              ++ I  L  + K+ E++I   K        +  ++ S+I ++ LI    EELN +I  
Sbjct: 1350 VKDELIYKLQQQVKKLEISIKEKKEQIKQFKQDISERSSQISQIDLIDREKEELNDQIRL 1409

Query: 1498 SVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKH 1557
                 + + +    L+ +++K  +    L   ++E+    D + +++N ++    +I + 
Sbjct: 1410 KEKSEESLKQTISTLQSQISKLTKQVQQLIQDKMELQQQIDRLIDIENSIKLKEIEILRL 1469

Query: 1558 VSFASDTKQGRDEQLDNTMNKELLDAVPRAEL 1589
            V   +D +  R ++   T++K + D   + ++
Sbjct: 1470 VQIENDYQ--RQKEKVKTLDKTITDQTQKIKI 1499



 Score =  168 bits (408), Expect = 1e-39
 Identities = 235/1214 (19%), Positives = 532/1214 (43%), Gaps = 120/1214 (9%)

Query: 149  NTIKEKDNALSVLQVKMKI--METTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXX 206
            N+ KE D    + ++  +I   E +I  LQ++IN+ + +I+ K++               
Sbjct: 786  NSNKENDLTKEIQELHQQINKYEQSIKQLQDQINKLENLIKYKDQQLKKHELQQDSWKDN 845

Query: 207  XXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFE 266
                    ++  T+        + + K+  ++L   ++SK+  I  L++          E
Sbjct: 846  LSKLENQIEELETQQLRELKQQDKQNKETIKKLENQLKSKEHEIKKLQD----------E 895

Query: 267  ISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMT-ELT 325
            I L+  K+ Q LEQ                      S ++  E++ K  L I     E+ 
Sbjct: 896  IKLQQEKI-QSLEQMIEQ-----------INDQFHTSQQQLNEVQLKFQLTIREKDFEIN 943

Query: 326  K-KIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKS 384
            K K +L    + +I+     L  ++    TE   V   + + S  I     RN     K 
Sbjct: 944  KLKQKLGSQKSPEIQSEIDSLHQQIIEKETEIIKVREDTSELSQKI-----RNYELDFKK 998

Query: 385  PWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXG 444
                   ET+ ++  KK+ +    +LE++I  L       +  I ++++           
Sbjct: 999  -----FQETI-KEYQKKLERT--TQLEILISELKIKDETNQVKIDDQNSTINNQDAIIQS 1050

Query: 445  KDTLIAQLQLEHQQH-MEGPSLIHVGTNTEDVNEIAKVQEQLKQEL-NDEIKDVNVKDLI 502
            KD  I +LQ + ++   +G  LI+V        ++ + ++QL + L N  I    +  L 
Sbjct: 1051 KDQTIKKLQEQQREFTKKGDQLINV------QKKLIETEQQLHEALQNASISQDKINTLE 1104

Query: 503  EKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTE 562
            ++L   + ++ +L D+I    + + +++S    K +  QKTI+  +K+ +   +I +L +
Sbjct: 1105 QQLALKDLELKKLKDQIKEIQREVERLQSKLYEKEQLQQKTIEQQNKIEELENQIEKLKQ 1164

Query: 563  ELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQ 622
            E    SQ+   LE++   L+     Y   + +  +  + +  +E   ++  + I + E +
Sbjct: 1165 ENKKKSQENQVLEDKVQQLKKLEEKYKKQQNLIEEHKQTLESLERKIKSLEEQIQINEDE 1224

Query: 623  KFDLVQELHILQQKYDEVEDKLADISQLQS---DQVCSEIKSVHLEEQIDALSASKKELA 679
            K+ L +E+ +L++K ++   +  +    Q+   D + +++K    E  ++ L A   E  
Sbjct: 1225 KYSLEREVDLLKKKLEDERKQFENKINQQARAKDDIIAKLKEKIAE--LEKLEAQHFEFT 1282

Query: 680  LVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKL--EKMSAEKISELLA 737
              +E+LK +K+        L++D      +++   Q+   L +KL  E+ S + +   + 
Sbjct: 1283 QEVEDLKEEKKSRKNIESKLQSDNSIYQKQIKQLEQQIKSLQEKLKSEEESNKILHNEIE 1342

Query: 738  KINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLER 797
            +IN   + K +  + +  ++++ ++ I+  + ++ ++K  I      I+ ++     ++R
Sbjct: 1343 QINVNIKVKDELIYKLQQQVKKLEISIKEKKEQIKQFKQDISERSSQISQID----LIDR 1398

Query: 798  KADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQI 857
            + ++L   ++ K+K+       E+ L   ++ L      + KQ+ ++  +  ELQ++   
Sbjct: 1399 EKEELNDQIRLKEKS-------EESLKQTISTLQSQISKLTKQVQQLIQDKMELQQQIDR 1451

Query: 858  LLEENQNLQIS------LSDMQQHYNALVEKANRTDLAESEST-------KYQTQLRDLE 904
            L++   ++++       L  ++  Y    EK    D   ++ T       +Y+ Q ++  
Sbjct: 1452 LIDIENSIKLKEIEILRLVQIENDYQRQKEKVKTLDKTITDQTQKIKIYQEYEKQTKESI 1511

Query: 905  SNLKRITHEHQTLIVQKKKEIEDLE---IEFNTQIESAIRDKKVLNEKYEKN----IEYV 957
             N ++   E Q  I   ++EI  L+    ++  QI    ++K+ +N+K + +     + +
Sbjct: 1512 KNYEQELDEKQETIQHLEQEIIKLKQQIDDYQRQITKISKEKETVNQKVKSSETNQQKKI 1571

Query: 958  TQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNAL 1017
             QLE Q QE  N+++ LN+ VE+L     EL ++   + Q Q  D  ++ I   +  +  
Sbjct: 1572 DQLEEQKQELLNDLQTLNIRVEDLQSQLKELQER---RDQFQKIDKEKEDIKRTSDTSE- 1627

Query: 1018 LKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQH 1077
             ++  E I  L ++I   +   +    +   ++ Q   K + ++++  ++ +Q + + Q+
Sbjct: 1628 -RKYKESIKELEKEIQRLKAEMIKKEHNNSKEIEQQIDKAQKLKQQNTQL-EQTIKNLQN 1685

Query: 1078 NEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXX 1137
            NE+   L+ EQ +QI E  + KL  +  I       ++  I+ +++  N ++        
Sbjct: 1686 NEKKLKLLEEQCNQISERSQEKLNKKDQIIDD----LNKQIKNLNEQINKLNQKLKSVN- 1740

Query: 1138 XXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQIN 1197
                   ++EE+ I +    ++     N + ++ Y K           +  D   Q+   
Sbjct: 1741 -------KDEEDDIADFG--EDADVDDNNKTKKKYEK----------ESKKDKNEQKTNR 1781

Query: 1198 QLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHEL 1257
            QL+  +E+L  +N N    + +L   +    +Q   +   + KQ   Q+E D  +T  + 
Sbjct: 1782 QLEKDIEKLTQDNINKTQQIKQLEEQLKK--NQELIQKETIEKQQKTQKEKDENQTIKKQ 1839

Query: 1258 RVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVI 1317
              ++   + + ++L + +Q  T++ + +   +EQ+  L+ ++  K + +  LQE+   + 
Sbjct: 1840 ETEIKKKDEQIKKLQEEIQ-KTEKNSKEKDNLEQIKVLKQEIDQKTQQITKLQEQIQKL- 1897

Query: 1318 NQIEILRSEIEDEK 1331
             Q +I  S+ +DEK
Sbjct: 1898 -QKDISASKQKDEK 1910



 Score =  162 bits (394), Expect = 6e-38
 Identities = 255/1148 (22%), Positives = 512/1148 (44%), Gaps = 123/1148 (10%)

Query: 477  EIAKVQEQLKQELN---DEIKDVN----VKDLIEKLKSAEEQITQLNDEIDAANKNMIKV 529
            +I ++ +Q++ E+N   D++KD+     VKD  +++K  +EQ+ +LN  ++ +N    ++
Sbjct: 517  KIEQINKQMQDEINFFEDQMKDLQDSLRVKD--QEVKKLQEQMKELNKTLEKSNIQSDQI 574

Query: 530  KSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYD 589
            +  H+    Q Q   +   K+     EI    +E+  L +K  +L+      QL L DY+
Sbjct: 575  EKLHQEAHSQTQLLEELEQKIQQQEYEIKTKEQEIKRLKEKNRDLQL----YQLKLKDYE 630

Query: 590  SGRMIESDVYKKMIE-MENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADIS 648
                I S   K+ IE + ++ + + + I  LE        +L    ++  E+ +K+ +++
Sbjct: 631  EN--INS--LKEEIERLNSIDKQQQENIYKLEQSHKTKEYQLSKYSEQTKEMTNKVKELN 686

Query: 649  QLQSDQVCSEI-KSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIM 707
            + ++ ++   I ++  L+EQ+       K+L   I+  +   E+   T K L+ + +D+ 
Sbjct: 687  EEKTSEIRKFIIQNEELQEQVRIFEIEVKKLQSNIQGNQRTPER---TTK-LQQELDDLY 742

Query: 708  NKLQNYIQENMDLTDKLEKMSAE-KISEL----LAKINHEEQSKIQTQFGIDAKIQERDL 762
            +KL   I EN DL  +++ +S + K+ E     L +I  E Q     +  +  +IQE   
Sbjct: 743  DKLNQQIGENADLKIQIQNLSTQIKLKEQEIKKLLEIQLEIQQNSNKENDLTKEIQELHQ 802

Query: 763  YIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQE-D 821
             I   E  + + + +I +LE  I   + +    E + D     L + +    E   Q+  
Sbjct: 803  QINKYEQSIKQLQDQINKLENLIKYKDQQLKKHELQQDSWKDNLSKLENQIEELETQQLR 862

Query: 822  ELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVE 881
            EL  +     +  + +E QL   EHE K+LQ + ++  E+ Q+L+  +  +   ++   +
Sbjct: 863  ELKQQDKQNKETIKKLENQLKSKEHEIKKLQDEIKLQQEKIQSLEQMIEQINDQFHTSQQ 922

Query: 882  KANRTDLA--------ESESTKYQTQLRDLESN--LKRITHEHQTLIVQKKKEI----ED 927
            + N   L         + E  K + +L   +S      I   HQ  I++K+ EI    ED
Sbjct: 923  QLNEVQLKFQLTIREKDFEINKLKQKLGSQKSPEIQSEIDSLHQQ-IIEKETEIIKVRED 981

Query: 928  LEIEFNTQIESAIRDKKVLNE---KYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKM 984
               E + +I +   D K   E   +Y+K +E  TQLE  + E K   E   + +++ N  
Sbjct: 982  TS-ELSQKIRNYELDFKKFQETIKEYQKKLERTTQLEILISELKIKDETNQVKIDDQNST 1040

Query: 985  --NLELI----DKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVS 1038
              N + I    D+ ++K Q Q  ++T++    IN    L++ + +    L++ + NA +S
Sbjct: 1041 INNQDAIIQSKDQTIKKLQEQQREFTKKGDQLINVQKKLIETEQQ----LHEALQNASIS 1096

Query: 1039 YMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKET 1098
                ++  E +LA    +L+ ++++++ + +++       E LQ  + E++    +L++ 
Sbjct: 1097 -QDKINTLEQQLALKDLELKKLKDQIKEIQREV-------ERLQSKLYEKE----QLQQK 1144

Query: 1099 KLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQ 1158
             +  +  I + E  I     E +  +                 LK + EE++ +++++++
Sbjct: 1145 TIEQQNKIEELENQI-----EKLKQENKKKSQENQVLEDKVQQLK-KLEEKYKKQQNLIE 1198

Query: 1159 EQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVA 1218
            E    L  E  E   K ++ +    E   + +  + +++ LK KLE    + +N ++  A
Sbjct: 1199 EHKQTL--ESLERKIKSLEEQIQINEDEKYSL--EREVDLLKKKLEDERKQFENKINQQA 1254

Query: 1219 ELRSSISSAVDQRGFEIAELWKQHLA-QREADFQKTEHELRVQLSAFESKYEQLLDSVQS 1277
              +  I + + ++  E+ +L  QH    +E +  K E + R  +   ESK    L S  S
Sbjct: 1255 RAKDDIIAKLKEKIAELEKLEAQHFEFTQEVEDLKEEKKSRKNI---ESK----LQSDNS 1307

Query: 1278 STQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXX 1337
              Q++  ++   +Q+ SLQ KL+ +EE  + L  +    I QI +   +++DE +     
Sbjct: 1308 IYQKQIKQLE--QQIKSLQEKLKSEEESNKILHNE----IEQINV-NIKVKDELI----- 1355

Query: 1338 XXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVND 1397
                          ++ + +  KQ ++    +I+E ++Q+ +              ++  
Sbjct: 1356 -YKLQQQVKKLEISIKEKKEQIKQFKQ----DISERSSQISQIDLIDREKEELND-QIRL 1409

Query: 1398 AEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKES 1457
             E     L   +    S+I + T +    L Q   E +    +L++ E  I      K  
Sbjct: 1410 KEKSEESLKQTISTLQSQISKLTKQVQ-QLIQDKMELQQQIDRLIDIENSI------KLK 1462

Query: 1458 ELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVA 1517
            E+ ILRL   EN   Y+  QKE      K I +   KI       KQ  E  K  E+E+ 
Sbjct: 1463 EIEILRLVQIEN--DYQR-QKEKVKTLDKTITDQTQKIKIYQEYEKQTKESIKNYEQEL- 1518

Query: 1518 KTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSK---IQKHVSFASDTKQGRDEQLDN 1574
              +E Q  +++ E EI+ L  +I + Q  +   S +   + + V  +   +Q + +QL+ 
Sbjct: 1519 --DEKQETIQHLEQEIIKLKQQIDDYQRQITKISKEKETVNQKVKSSETNQQKKIDQLEE 1576

Query: 1575 TMNKELLD 1582
               +ELL+
Sbjct: 1577 -QKQELLN 1583



 Score =  153 bits (370), Expect = 5e-35
 Identities = 211/1075 (19%), Positives = 472/1075 (43%), Gaps = 74/1075 (6%)

Query: 158  LSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQ 217
            +S L++K +  +  I D    IN +D II++K++                       K+ 
Sbjct: 1020 ISELKIKDETNQVKIDDQNSTINNQDAIIQSKDQTIKKLQEQQREFTKKGDQLINVQKKL 1079

Query: 218  MTKMQENFIAME--AEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLA 275
            +   Q+   A++  +  +D+   L + +  KD+ +  L++  K ++    E+    SKL 
Sbjct: 1080 IETEQQLHEALQNASISQDKINTLEQQLALKDLELKKLKDQIKEIQR---EVERLQSKL- 1135

Query: 276  QELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLE--IANMTELTKKIELLEH 333
             E EQ              L  Q  +   E K + +E   LE  +  + +L +K +  ++
Sbjct: 1136 YEKEQLQQKTIEQQNKIEELENQIEKLKQENKKKSQENQVLEDKVQQLKKLEEKYKKQQN 1195

Query: 334  LNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSET 393
            L  + +QT + LE K+ ++  E   ++   K           +    + K   ++++ + 
Sbjct: 1196 LIEEHKQTLESLERKIKSL-EEQIQINEDEKYSLEREVDLLKKKLEDERKQFENKINQQA 1254

Query: 394  LNQDTDKKINKNEIAKLEMV----------IQSLNKDLVDKEYVISEKDTXXXXXXXXXX 443
              +D      K +IA+LE +          ++ L ++   ++ + S+  +          
Sbjct: 1255 RAKDDIIAKLKEKIAELEKLEAQHFEFTQEVEDLKEEKKSRKNIESKLQSDNSIYQKQIK 1314

Query: 444  GKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIK--DVNVKDL 501
              +  I  LQ + +   E   ++H     E +N   KV+++L  +L  ++K  ++++K+ 
Sbjct: 1315 QLEQQIKSLQEKLKSEEESNKILH--NEIEQINVNIKVKDELIYKLQQQVKKLEISIKEK 1372

Query: 502  IEKLKSAEEQITQLNDEIDAANK-NMIKVKSNHKLKLKQMQKTIDNFSK-VSDSNKEIVR 559
             E++K  ++ I++ + +I   +  +  K + N +++LK+  K+ ++  + +S    +I +
Sbjct: 1373 KEQIKQFKQDISERSSQISQIDLIDREKEELNDQIRLKE--KSEESLKQTISTLQSQISK 1430

Query: 560  LTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLL 619
            LT+++  L Q   EL+++   L    +D ++   ++     +++++EN  + + + +  L
Sbjct: 1431 LTKQVQQLIQDKMELQQQIDRL----IDIENSIKLKEIEILRLVQIENDYQRQKEKVKTL 1486

Query: 620  ESQKFDLVQELHILQQKYDEVEDKLADISQ-LQSDQVCS---EIKSVHLEEQID----AL 671
            +    D  Q++ I Q+   + ++ + +  Q L   Q      E + + L++QID     +
Sbjct: 1487 DKTITDQTQKIKIYQEYEKQTKESIKNYEQELDEKQETIQHLEQEIIKLKQQIDDYQRQI 1546

Query: 672  SASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEK 731
            +   KE   V + +K  +      I  LE  K++++N LQ       DL  +L+++   +
Sbjct: 1547 TKISKEKETVNQKVKSSETNQQKKIDQLEEQKQELLNDLQTLNIRVEDLQSQLKELQERR 1606

Query: 732  ISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEES----IAV 787
              +   KI+ E++   +T    + K +E    I+ +E E+ + K+ + + E +    I  
Sbjct: 1607 --DQFQKIDKEKEDIKRTSDTSERKYKES---IKELEKEIQRLKAEMIKKEHNNSKEIEQ 1661

Query: 788  MEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAV-----LMDHDRVVEKQLL 842
              D+   L+++  QL   ++  Q    +  + E++  N+++      L   D++++    
Sbjct: 1662 QIDKAQKLKQQNTQLEQTIKNLQNNEKKLKLLEEQC-NQISERSQEKLNKKDQIIDDLNK 1720

Query: 843  EIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLA-ESESTKYQTQL- 900
            +I++ N+++ K NQ L   N++ +  ++D  +  +A V+  N+T    E ES K + +  
Sbjct: 1721 QIKNLNEQINKLNQKLKSVNKDEEDDIADFGE--DADVDDNNKTKKKYEKESKKDKNEQK 1778

Query: 901  --RDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNT-QIESAIRDKKVLNEKYE-----K 952
              R LE +++++T ++     Q K+  E L+      Q E+  + +K   EK E     K
Sbjct: 1779 TNRQLEKDIEKLTQDNINKTQQIKQLEEQLKKNQELIQKETIEKQQKTQKEKDENQTIKK 1838

Query: 953  NIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEIN 1012
                + + + Q+++ +  I+    N +E + +    + K    Q+TQ     ++ I ++ 
Sbjct: 1839 QETEIKKKDEQIKKLQEEIQKTEKNSKEKDNLEQIKVLKQEIDQKTQQITKLQEQIQKLQ 1898

Query: 1013 KLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLL 1072
            K  +  KQKDE+     Q++   +     +    E    +   K +N + + + + KQ  
Sbjct: 1899 KDISASKQKDEKNNKSEQELKKKEEEISKLKEKIEKDSKETNEKKQNEKNQNELIKKQQE 1958

Query: 1073 DSKQHNEELQILVREQD------DQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDAN 1126
            + K+  EE +    + +      DQ+ +L++ K T +  I K E  I    ++   DD  
Sbjct: 1959 EIKKKEEENKKFKDQTNENNKLKDQVSKLEKEKSTTDEKIKKQEDKI--KELQKQIDDQK 2016

Query: 1127 NVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETL 1181
                            +  ++    Q  +  +E   KL  ++ E    II LE+L
Sbjct: 2017 QKTPTNNRDDPNDKQGQSDKKPGPYQNDTKYKELVIKLEKQIDELKIHIIYLESL 2071



 Score =  151 bits (365), Expect = 2e-34
 Identities = 237/1148 (20%), Positives = 493/1148 (42%), Gaps = 103/1148 (8%)

Query: 471  NTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVK 530
            N+  + ++ +  +QL QEL+   K +  +D  +     EE + + + EI+   + +I++ 
Sbjct: 135  NSNKLKQLEEQNQQLIQELDLITKRLLDRDNAQGTVDYEELLRERDQEIEILTQQIIQIS 194

Query: 531  SNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDS 590
            +N         K +  F   SD      ++TE   +  Q + EL+E+   L++ +++ D 
Sbjct: 195  NN---------KQVKQFDPSSDKR----QITETEEYYGQIIKELQEKIEQLRIIIIEKDD 241

Query: 591  GRMIESDVYKKMIEMENLAETRLKAISLLESQKF-------DLVQELHILQQKYDEVEDK 643
              + +      +IEME L    ++    +E  K        +L ++ H+++   + ++D 
Sbjct: 242  -HLNQGQNQSVLIEMETLQVQLIQYKIEIEGYKTRMQYIQNELSEKDHLIEDLQNIIKDL 300

Query: 644  LADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDK 703
               I   QS+ + + I   +  +                +    D  +    +   E D 
Sbjct: 301  TKKIQNRQSNDIQNPISPKNPNKSPSNSFNQNSNNPNKNQRNPGDATKNAADVFQQEEDN 360

Query: 704  EDIMNKLQNYIQENMDLTDKLEKMSAEKISE---LLAKINHEEQSKIQTQFGIDAKIQER 760
             D  +  +   ++   L    +K   + I +   ++A +  E Q   Q       KI ++
Sbjct: 361  YDQKDPNEEKKKKKHGLEGAKKKEDEDSIKDYQKIIANLKAENQRLQQELNQAIFKINQQ 420

Query: 761  DLYIENIESELSKYKSRICRLEESIAVMED---RRYSLERKADQLGSYLQEKQKAYSEYT 817
            +  I   +++LS  + R    E+ I  ++D   ++Y LE++  QL   L E ++   +  
Sbjct: 421  EALINEKDNQLSLLELR----EKEIRQLKDQLNKQYKLEQENKQLEKKLGEMEQKIQDLM 476

Query: 818  IQ-----EDELVN---RLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISL 869
            ++     +D  +N   +     D+ + ++KQ  E+    K++++ N+ + +E    +  +
Sbjct: 477  LEIENYDQDNKLNEKKQSKKEADYQKALQKQKDELLANQKKIEQINKQMQDEINFFEDQM 536

Query: 870  SDMQQHYNALVEKANR--TDLAESESTKYQTQLR-DLESNLKRITHEHQTLIVQKKKEIE 926
             D+Q       ++  +    + E   T  ++ ++ D    L +  H    L+ + +++I+
Sbjct: 537  KDLQDSLRVKDQEVKKLQEQMKELNKTLEKSNIQSDQIEKLHQEAHSQTQLLEELEQKIQ 596

Query: 927  DLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNL 986
              E E  T+ E  I+  K  N   +     +   E  +   K  IE LN ++++  + N+
Sbjct: 597  QQEYEIKTK-EQEIKRLKEKNRDLQLYQLKLKDYEENINSLKEEIERLN-SIDKQQQENI 654

Query: 987  ELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEI---IALNQKINNA----QVSY 1039
              +++  + ++ Q   Y+EQ     NK+  L ++K  EI   I  N+++       ++  
Sbjct: 655  YKLEQSHKTKEYQLSKYSEQTKEMTNKVKELNEEKTSEIRKFIIQNEELQEQVRIFEIEV 714

Query: 1040 MSMVSDYE--SKLAQFTTKL-ENMEEEMQRVSKQL---LDSKQHNEELQILVREQDDQIK 1093
              + S+ +   +  + TTKL + +++   ++++Q+    D K   + L   ++ ++ +IK
Sbjct: 715  KKLQSNIQGNQRTPERTTKLQQELDDLYDKLNQQIGENADLKIQIQNLSTQIKLKEQEIK 774

Query: 1094 ELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLK--VQEEEEFI 1151
            +L E +L  + N  K     ++  I+ +    N  +            L+  ++ +++ +
Sbjct: 775  KLLEIQLEIQQNSNKEND--LTKEIQELHQQINKYEQSIKQLQDQINKLENLIKYKDQQL 832

Query: 1152 QERSVLQEQSAKLNTELQECYTKIIQLETLN-TELTGHDVVNQEQI----NQLKSKLEQL 1206
            ++   LQ+ S K N  L +   +I +LET    EL   D  N+E I    NQLKSK  ++
Sbjct: 833  KKHE-LQQDSWKDN--LSKLENQIEELETQQLRELKQQDKQNKETIKKLENQLKSKEHEI 889

Query: 1207 NTENDNL---LSTVAELRSSISSAVDQRGFEIAEL----WKQHLAQREADFQKTEHELRV 1259
                D +      +  L   I    DQ      +L     K  L  RE DF+   ++L+ 
Sbjct: 890  KKLQDEIKLQQEKIQSLEQMIEQINDQFHTSQQQLNEVQLKFQLTIREKDFE--INKLKQ 947

Query: 1260 QLSAFES-KYEQLLDSV-QSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQE------ 1311
            +L + +S + +  +DS+ Q   ++ET  I   E  + L  K+++ E   +  QE      
Sbjct: 948  KLGSQKSPEIQSEIDSLHQQIIEKETEIIKVREDTSELSQKIRNYELDFKKFQETIKEYQ 1007

Query: 1312 KYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQ--SILN 1369
            K  +   Q+EIL SE++ +                     +++++Q+ K++QEQ      
Sbjct: 1008 KKLERTTQLEILISELKIKDETNQVKIDDQNSTINNQDAIIQSKDQTIKKLQEQQREFTK 1067

Query: 1370 INEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQ 1429
              ++   ++K                + ++ K+  L  QL LKD E+  K  +  I   Q
Sbjct: 1068 KGDQLINVQKKLIETEQQLHEALQNASISQDKINTLEQQLALKDLEL--KKLKDQIKEIQ 1125

Query: 1430 RNDEFENVRQQLVEYE----KRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERV 1485
            R  E E ++ +L E E    K IE     +E E  I +LK        E    E +++++
Sbjct: 1126 R--EVERLQSKLYEKEQLQQKTIEQQNKIEELENQIEKLKQENKKKSQENQVLEDKVQQL 1183

Query: 1486 KLIEELNVKITESVSLNKQVAE----LNKALEEEVAKTNEMQTALENQEIEIV--TLNDE 1539
            K +EE   K    +  +KQ  E      K+LEE++    + + +LE +E++++   L DE
Sbjct: 1184 KKLEEKYKKQQNLIEEHKQTLESLERKIKSLEEQIQINEDEKYSLE-REVDLLKKKLEDE 1242

Query: 1540 ITNLQNMV 1547
                +N +
Sbjct: 1243 RKQFENKI 1250



 Score = 85.8 bits (203), Expect = 9e-15
 Identities = 178/937 (18%), Positives = 393/937 (41%), Gaps = 51/937 (5%)

Query: 658  EIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQEN 717
            EIK   L    D L+A  +E     E LK + + LY   KDL     ++ ++L+  I+ N
Sbjct: 22   EIKIKQLLRANDKLNAVVRETLAENEQLKGNIDVLYKENKDLNRLNIELCDQLER-IKRN 80

Query: 718  M---DLTDKLEKMSAEKISE--LLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELS 772
                   DK      ++I++  LL +   +E +  + ++  D +I+   +      ++L 
Sbjct: 81   TRQHSTHDKTIIDYEQEITQLKLLLQEKQKEVNSFKIRYNEDLQIKLDIVDKSGNSNKLK 140

Query: 773  KYKSRICRLEESIAVMEDRRYSLERKADQLG--SYLQEKQKAYSEYTIQEDELVNRLAVL 830
            + + +  +L + + ++  R    +     +     L+E+ +     T Q  ++ N   V 
Sbjct: 141  QLEEQNQQLIQELDLITKRLLDRDNAQGTVDYEELLRERDQEIEILTQQIIQISNNKQVK 200

Query: 831  MDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAE 890
                   ++Q+ E E    ++ K+   L E+ + L+I + +   H N   +  N++ L E
Sbjct: 201  QFDPSSDKRQITETEEYYGQIIKE---LQEKIEQLRIIIIEKDDHLN---QGQNQSVLIE 254

Query: 891  SESTKYQTQLRDLE-SNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEK 949
             E+ + Q     +E    K      Q  + +K   IEDL+      +   I++++  +  
Sbjct: 255  METLQVQLIQYKIEIEGYKTRMQYIQNELSEKDHLIEDLQ-NIIKDLTKKIQNRQ--SND 311

Query: 950  YEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQT-QSPDYTEQYI 1008
             +  I      ++    +  N  N N N            D   Q++      D  E+  
Sbjct: 312  IQNPISPKNPNKSPSNSFNQNSNNPNKNQRNPGDATKNAADVFQQEEDNYDQKDPNEEKK 371

Query: 1009 NEINKLNALLKQKDEEIIALNQK-INNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRV 1067
             + + L    K++DE+ I   QK I N +     +    + +L Q   K+   E  +   
Sbjct: 372  KKKHGLEGAKKKEDEDSIKDYQKIIANLKAENQRL----QQELNQAIFKINQQEALINEK 427

Query: 1068 SKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANN 1127
              QL   +   +E++ L  + + Q K  +E K   E  + + E  I    +E  + D +N
Sbjct: 428  DNQLSLLELREKEIRQLKDQLNKQYKLEQENK-QLEKKLGEMEQKIQDLMLEIENYDQDN 486

Query: 1128 VDXXXXXXXXXXXXLKV--QEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTEL 1185
                           K   ++++E +  +  +++ + ++  E+     ++  L+  +  +
Sbjct: 487  KLNEKKQSKKEADYQKALQKQKDELLANQKKIEQINKQMQDEINFFEDQMKDLQD-SLRV 545

Query: 1186 TGHDVVN-QEQINQLKSKLEQLNTENDNL--LSTVAELRSSISSAVDQRGFEIAELWKQH 1242
               +V   QEQ+ +L   LE+ N ++D +  L   A  ++ +   ++Q+     +  +  
Sbjct: 546  KDQEVKKLQEQMKELNKTLEKSNIQSDQIEKLHQEAHSQTQLLEELEQK----IQQQEYE 601

Query: 1243 LAQREADFQKTEHELR-VQLSAFESK-YEQLLDSVQSSTQEETNKIVTMEQ--VTSLQNK 1298
            +  +E + ++ + + R +QL   + K YE+ ++S++    E  N I   +Q  +  L+  
Sbjct: 602  IKTKEQEIKRLKEKNRDLQLYQLKLKDYEENINSLKEEI-ERLNSIDKQQQENIYKLEQS 660

Query: 1299 LQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQS 1358
             + KE  L    E+  ++ N+++ L  E   E   F                +++ + QS
Sbjct: 661  HKTKEYQLSKYSEQTKEMTNKVKELNEEKTSEIRKFIIQNEELQEQVRIFEIEVK-KLQS 719

Query: 1359 YKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQ 1418
              Q  +++     E   +L++                 D + ++  L+ Q++LK+ EI +
Sbjct: 720  NIQGNQRT----PERTTKLQQELDDLYDKLNQQIGENADLKIQIQNLSTQIKLKEQEI-K 774

Query: 1419 KTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQ- 1477
            K  E  + + Q +++  ++ +++ E  ++I    YE+  +    ++   EN   Y+  Q 
Sbjct: 775  KLLEIQLEIQQNSNKENDLTKEIQELHQQIN--KYEQSIKQLQDQINKLENLIKYKDQQL 832

Query: 1478 KESEIERVKLIEELNVKITESVSL-NKQVAELNKALEEEVAKTNEMQTALENQEIEIVTL 1536
            K+ E+++    + L+    +   L  +Q+ EL +  ++      +++  L+++E EI  L
Sbjct: 833  KKHELQQDSWKDNLSKLENQIEELETQQLRELKQQDKQNKETIKKLENQLKSKEHEIKKL 892

Query: 1537 NDEITNLQNMVRASSSKIQK-HVSFASDTKQGRDEQL 1572
             DEI   Q  +++    I++ +  F +  +Q  + QL
Sbjct: 893  QDEIKLQQEKIQSLEQMIEQINDQFHTSQQQLNEVQL 929



 Score = 79.0 bits (186), Expect = 1e-12
 Identities = 121/636 (19%), Positives = 268/636 (42%), Gaps = 48/636 (7%)

Query: 930  IEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELI 989
            +   +Q +  I+ K++L    + N   V +  A+ ++ K NI+ L    ++LN++N+EL 
Sbjct: 13   LSHQSQDDYEIKIKQLLRANDKLNA-VVRETLAENEQLKGNIDVLYKENKDLNRLNIELC 71

Query: 990  D--KHVQKQQTQSPDYTE---QYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMV- 1043
            D  + +++   Q   + +    Y  EI +L  LL++K +E+ +   + N      + +V 
Sbjct: 72   DQLERIKRNTRQHSTHDKTIIDYEQEITQLKLLLQEKQKEVNSFKIRYNEDLQIKLDIVD 131

Query: 1044 -SDYESKLAQFTTKLENMEEEMQRVSKQLL--DSKQHNEELQILVREQDDQIKELKETKL 1100
             S   +KL Q   + + + +E+  ++K+LL  D+ Q   + + L+RE+D +I+ L +  +
Sbjct: 132  KSGNSNKLKQLEEQNQQLIQELDLITKRLLDRDNAQGTVDYEELLRERDQEIEILTQQII 191

Query: 1101 TFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQ 1160
                N    +        +P SD     +             ++QE+ E  Q R ++ E+
Sbjct: 192  QISNNKQVKQ-------FDPSSDKRQITETEEYYGQIIK---ELQEKIE--QLRIIIIEK 239

Query: 1161 SAKLN-----TELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLS 1215
               LN     + L E  T  +QL     E+ G+    Q   N+L  K + L  +  N++ 
Sbjct: 240  DDHLNQGQNQSVLIEMETLQVQLIQYKIEIEGYKTRMQYIQNELSEK-DHLIEDLQNIIK 298

Query: 1216 TVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSV 1275
             + +   +  S   Q         K        +        R    A ++  +      
Sbjct: 299  DLTKKIQNRQSNDIQNPISPKNPNKSPSNSFNQNSNNPNKNQRNPGDATKNAADVFQQEE 358

Query: 1276 QSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFX 1335
             +  Q++ N+    ++      K ++ E+ +++ Q+  A++  + + L+ E+ ++ +   
Sbjct: 359  DNYDQKDPNEEKKKKKHGLEGAKKKEDEDSIKDYQKIIANLKAENQRLQQEL-NQAIFKI 417

Query: 1336 XXXXXXXXXXXXXXXDLRTENQSYKQMQEQ--SILNINEENAQLKKSSXXXXXXXXXXXX 1393
                            L    +  +Q+++Q      + +EN QL+K              
Sbjct: 418  NQQEALINEKDNQLSLLELREKEIRQLKDQLNKQYKLEQENKQLEKK-------LGEMEQ 470

Query: 1394 RVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTY 1453
            ++ D   ++       +L + +  +K  +Y   L ++ DE       L+  +K+IE +  
Sbjct: 471  KIQDLMLEIENYDQDNKLNEKKQSKKEADYQKALQKQKDE-------LLANQKKIEQINK 523

Query: 1454 EKESELAILRLKMHENANHYETMQKESEIERV-KLIEELNVKITESVSLNKQVAELNKAL 1512
            + + E+     +M +  +      K+ E++++ + ++ELN  + +S   + Q+ +L++  
Sbjct: 524  QMQDEINFFEDQMKDLQDSLRV--KDQEVKKLQEQMKELNKTLEKSNIQSDQIEKLHQEA 581

Query: 1513 EEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVR 1548
              +     E++  ++ QE EI T   EI  L+   R
Sbjct: 582  HSQTQLLEELEQKIQQQEYEIKTKEQEIKRLKEKNR 617


>UniRef50_UPI00015B5D72 Cluster: PREDICTED: similar to viral A-type
            inclusion protein, putative; n=1; Nasonia
            vitripennis|Rep: PREDICTED: similar to viral A-type
            inclusion protein, putative - Nasonia vitripennis
          Length = 3263

 Score =  197 bits (481), Expect = 2e-48
 Identities = 302/1431 (21%), Positives = 609/1431 (42%), Gaps = 162/1431 (11%)

Query: 212  EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271
            +D   ++T++      +EA   D    L ++++ KD  I S  +A  L+ A   ++S++ 
Sbjct: 186  QDKDNKITELSNKIFELEAVIID----LQENLKEKDSVIDSKTKAITLMSA---DLSMKG 238

Query: 272  SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELL 331
                  LE               L + S++   E+   +EE     +    E  K+ E +
Sbjct: 239  KTTLDTLEDTKDEMRSMQENFV-LVESSLKKKAEQIATLEENVQ-SLTEKLEAQKQAETV 296

Query: 332  E-HLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLS 390
                +     T  + ++ + +M      + +  K  +  + ++         +S    L+
Sbjct: 297  SADFSRSTMDTLADTKDAMKSMQENFVLIETSLKSKNEHLLKQLEEREIKLAESEARILN 356

Query: 391  SETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVIS-------EKDTXXXXXXXXXX 443
             ET     +++ N  EI      ++ +N+ L D++Y +        +K            
Sbjct: 357  LET-GLGIERQPNVEEITYKVDKLEEMNRKLQDEKYELQKNIAELQDKIISTESRTDESI 415

Query: 444  GKDTLIAQLQL------EHQQHMEGPSLIHVGTNTEDVNE--------IAKVQEQLKQEL 489
             +D  IA+L+       +  QH+E      +     ++NE        I ++++Q+    
Sbjct: 416  MEDNRIAELESLIEELKKSNQHLEEEYKAALHNQVAEMNERNETLSNKIVELEKQVNDVT 475

Query: 490  NDEIKDVNVKDLIE-KLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFS 548
            ND+I+  +    IE +    +EQ+ +L  E++  NK+MIK+K+ HK KLK +QK ++NF 
Sbjct: 476  NDKIELESKLSAIETEAPKEDEQVQKLTKELEELNKSMIKLKAQHKNKLKNLQKQLENFK 535

Query: 549  KVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENL 608
            KVSD N E+V+       L  +VA LEEEKGNLQL LVD+D  +    D  +++ ++E  
Sbjct: 536  KVSDKNAELVK-------LGNQVALLEEEKGNLQLSLVDFDELKASAGDWKERIADLEGK 588

Query: 609  A-------ETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKS 661
                    ET ++AI++LE+QK DL+QELH ++Q+   +E + A+   L   +V +E+K 
Sbjct: 589  VASQAKEIETHIEAIAILENQKLDLMQELHAVKQEVSSLEAENAESENL---RVTAEMKV 645

Query: 662  VHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLT 721
            V LEE+I++                L K+Q    + D E  + +   +++N  QEN  L+
Sbjct: 646  VDLEEEIES----------------LHKQQQAEPLTDAE--RIEFQRQIENLTQENERLS 687

Query: 722  DKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRL 781
             K+ K+   K S  +       +S ++T   +D+         +  +++L +    + R 
Sbjct: 688  QKVSKLEELKSSSEVG----STESFVKTGSNVDSTESFEAFAADADKADLLRKIDGLTR- 742

Query: 782  EESIAVMEDRRYSLERKADQLGSYLQ-EKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQ 840
             E+ A++E      E+ +   GS    E+   + E T + + L        +++ VV+  
Sbjct: 743  -ENGALLEKLTRFEEKGSSDTGSTESFERIPEHGESTSRLENLTRE-----NYELVVKLT 796

Query: 841  LLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQL 900
             LE +    E   K Q +L+EN+ L   L  +++  NA+VE+  R    E  S + +   
Sbjct: 797  KLEEKLAASEADTKLQEVLQENERLVAKLKQLEE--NAVVEEVVR----EKRSVEVEEVP 850

Query: 901  RDLESNLKRITHEHQT-LIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQ 959
            R  E  ++  + E  T ++V+  +    +  E   +IE      + +  + E       +
Sbjct: 851  RTQEPEIEETSSEAPTEVLVESTESPPHIVDELVAKIEELKSSLEAIGREKE-------E 903

Query: 960  LEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLK 1019
            L A+L+E +   + L +  E +      ++    Q    Q P   E       K +A+  
Sbjct: 904  LAAKLKEKEPVAQELQVE-ETIVPAEASVVKSSAQ----QDPSEAEL------KSDAV-- 950

Query: 1020 QKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNE 1079
             + E I AL ++I        +++++ ++ +    TKL + EEE++R S QL  S+ H++
Sbjct: 951  -QSEAIAALEREIERC----TALIAEQKAVIEDLKTKLADKEEELERKSAQLASSESHDQ 1005

Query: 1080 ---ELQILVREQDDQIKELKETK-----LTFEMNIPKTEGMIISSTIEPMSDDANNVDXX 1131
               +  +L RE ++   E+ E K     +  +M + +     I    + +  +  N+   
Sbjct: 1006 DQLDAHVLRRELEESASEIAEWKHKCAEMEEKMKVLEKGRQHIEEGFQALQTENKNLLEQ 1065

Query: 1132 XXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVV 1191
                      LK +E +  I +     E  ++   E+     +++  E L   +   D+ 
Sbjct: 1066 SEHKDVMLSQLK-EELDHTISD----FEAKSRAQGEVIASQEQLV--EELRKNVEEKDLE 1118

Query: 1192 NQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQ 1251
             Q + +QL++ L +++   D L        + + + V QR   IA L  + +     +  
Sbjct: 1119 LQGKYSQLQNDLIKMDELQDKL--------ARLEAQVQQRDATIASL-TEEVETLRTNAS 1169

Query: 1252 KTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQ-------VTSLQNKLQDKEE 1304
              E +L +        +E+L D   S + EE N++  MEQ       V  L+ KL  K  
Sbjct: 1170 VVEEDLFMARHQLTDLHEKLKD---SKSLEEYNQL--MEQLNDKTMLVEELETKLSQKLA 1224

Query: 1305 HLRNLQEKYADVINQIEILRS--EIEDEKVA----FXXXXXXXXXXXXXXXXDLRTENQS 1358
             +  L+ +   ++++   LR   ++++ ++A                     D+      
Sbjct: 1225 EVNALKAQVESLVSENHQLREQFQVDERRIADLLDDNHNQEEALRSSERAKADVENRLLD 1284

Query: 1359 YKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEI-- 1416
             + + E+++ +      +L+ S              ++    ++ ++  +LELK  EI  
Sbjct: 1285 LQDVHEENLRHAKNVTTELQNSYKMIEQLKIKHTEDMDMLNRRLEDVIEELELKSQEITS 1344

Query: 1417 YQKTHEYTITLTQRNDEFE---NVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHY 1473
             Q   E    L  ++   E    +  QL E   ++ +   E ++   + ++K +      
Sbjct: 1345 MQNELEEKTALVSKSMSEEVKLGLETQLAELSTKLTEA--EDKAHAQLEKMKKYAAVAKK 1402

Query: 1474 ETMQ-KESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIE 1532
            +T Q +E E +  +L E LN++  E    N+++ E     +E+  +  EM   L   ++E
Sbjct: 1403 KTAQCEELETKLRELEESLNLEKIEKELRNRELHEAIAGHQEKDNRIVEMDEELRRIQVE 1462

Query: 1533 IVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDA 1583
                   +  ++  +R ++ K+        +  + +D   +  +  ++++A
Sbjct: 1463 RDEAVQNVEAIKQELRQATDKLSTMNEEMQELSEAKDNARELGVRMQVIEA 1513



 Score =  171 bits (415), Expect = 2e-40
 Identities = 297/1476 (20%), Positives = 628/1476 (42%), Gaps = 106/1476 (7%)

Query: 144  VTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXX 203
            V  LS+ +++KDN ++ L  K+  +E  I+DLQE + EKD +I++K KA T         
Sbjct: 179  VMELSH-VQDKDNKITELSNKIFELEAVIIDLQENLKEKDSVIDSKTKAITLMSADLSMK 237

Query: 204  XXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAA 263
                    EDTK +M  MQENF+ +E+  K +K   +  +E     ++   EA K  E  
Sbjct: 238  GKTTLDTLEDTKDEMRSMQENFVLVESSLK-KKAEQIATLEENVQSLTEKLEAQKQAETV 296

Query: 264  RFEIS------LEHSKLAQE--LEQXXXXXXXXXXXXXXLAKQ----SIEPSCEEKTEIE 311
              + S      L  +K A +   E               L KQ     I+ +  E   + 
Sbjct: 297  SADFSRSTMDTLADTKDAMKSMQENFVLIETSLKSKNEHLLKQLEEREIKLAESEARILN 356

Query: 312  EKGSLEI---ANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSP 368
             +  L I    N+ E+T K++ LE +N +++    EL+  +A +  + K +S+ S+    
Sbjct: 357  LETGLGIERQPNVEEITYKVDKLEEMNRKLQDEKYELQKNIAEL--QDKIISTESRTDES 414

Query: 369  LISRKSGRNTASKMKSPWSQLSSETLNQDTD-KKINKNEIAKLEMVIQSLNKDLVDKEYV 427
            ++      N  ++++S   +L     + + + K    N++A++    ++L+  +V+ E  
Sbjct: 415  IME----DNRIAELESLIEELKKSNQHLEEEYKAALHNQVAEMNERNETLSNKIVELEKQ 470

Query: 428  ISEKDTXXXXXXXXXXGKDTLIAQLQLEHQ---QHMEGPSLIHVGTNTEDVNEIAKVQEQ 484
            +++               +T   +   + Q   + +E  +   +    +  N++  +Q+Q
Sbjct: 471  VNDVTNDKIELESKLSAIETEAPKEDEQVQKLTKELEELNKSMIKLKAQHKNKLKNLQKQ 530

Query: 485  LKQELNDEIKDVNVKDLIEKLKSAEEQITQLN------DEIDAANKNMIKVKSNHKLKLK 538
            L+       K+  +  L  ++   EE+   L       DE+ A+  +  +  ++ + K+ 
Sbjct: 531  LENFKKVSDKNAELVKLGNQVALLEEEKGNLQLSLVDFDELKASAGDWKERIADLEGKVA 590

Query: 539  QMQKTID-NFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESD 597
               K I+ +   ++    + + L +ELH + Q+V+ LE E    +   V  +  ++++ +
Sbjct: 591  SQAKEIETHIEAIAILENQKLDLMQELHAVKQEVSSLEAENAESENLRVTAEM-KVVDLE 649

Query: 598  VYKKMIEMENLAETRLKAISL-LESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVC 656
               + +  +  AE    A  +  + Q  +L QE   L QK  ++E+  +      ++   
Sbjct: 650  EEIESLHKQQQAEPLTDAERIEFQRQIENLTQENERLSQKVSKLEELKSSSEVGSTESFV 709

Query: 657  SEIKSVHLEEQIDALS--ASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNY- 713
                +V   E  +A +  A K +L   I+ L  +   L   +   E          +++ 
Sbjct: 710  KTGSNVDSTESFEAFAADADKADLLRKIDGLTRENGALLEKLTRFEEKGSSDTGSTESFE 769

Query: 714  -IQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELS 772
             I E+ + T +LE ++ E   EL+ K+   E+    ++   D K+QE     E + ++L 
Sbjct: 770  RIPEHGESTSRLENLTRENY-ELVVKLTKLEEKLAASE--ADTKLQEVLQENERLVAKLK 826

Query: 773  KYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQE-KQKAYSEYTIQEDELVNRLA-VL 830
            + +     +EE   V E R   +E         ++E   +A +E  ++  E    +   L
Sbjct: 827  QLEENAV-VEE--VVREKRSVEVEEVPRTQEPEIEETSSEAPTEVLVESTESPPHIVDEL 883

Query: 831  MDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANR-TDLA 889
            +     ++  L  I  E +EL  K +      Q LQ+  + +    + +   A +    A
Sbjct: 884  VAKIEELKSSLEAIGREKEELAAKLKEKEPVAQELQVEETIVPAEASVVKSSAQQDPSEA 943

Query: 890  ESESTKYQTQ-LRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVL-- 946
            E +S   Q++ +  LE  ++R T     LI ++K  IEDL+ +   + E   R    L  
Sbjct: 944  ELKSDAVQSEAIAALEREIERCT----ALIAEQKAVIEDLKTKLADKEEELERKSAQLAS 999

Query: 947  NEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEEL-NKMNL-----ELIDKHVQKQQTQS 1000
            +E ++++      L  +L+E  + I        E+  KM +     + I++  Q  QT++
Sbjct: 1000 SESHDQDQLDAHVLRRELEESASEIAEWKHKCAEMEEKMKVLEKGRQHIEEGFQALQTEN 1059

Query: 1001 PDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENM 1060
             +  EQ  ++   L+ L ++ D  I     K + AQ     +++  E  + +    +E  
Sbjct: 1060 KNLLEQSEHKDVMLSQLKEELDHTISDFEAK-SRAQ---GEVIASQEQLVEELRKNVEEK 1115

Query: 1061 EEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKET--KLTFEMNIPKTEGMIISSTI 1118
            + E+Q    QL +     +ELQ  +   + Q+++   T   LT E+   +T   ++   +
Sbjct: 1116 DLELQGKYSQLQNDLIKMDELQDKLARLEAQVQQRDATIASLTEEVETLRTNASVVEEDL 1175

Query: 1119 EPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVL-QEQSAKLNTELQECYTKIIQ 1177
                    ++              ++ E+   + ++++L +E   KL+ +L E      Q
Sbjct: 1176 FMARHQLTDLHEKLKDSKSLEEYNQLMEQ---LNDKTMLVEELETKLSQKLAEVNALKAQ 1232

Query: 1178 LETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSS--ISSAVDQRGFEI 1235
            +E+L +E   H +  Q Q+++   ++  L  +N N       LRSS    + V+ R  ++
Sbjct: 1233 VESLVSE--NHQLREQFQVDE--RRIADLLDDNHN---QEEALRSSERAKADVENRLLDL 1285

Query: 1236 AELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKI-VTMEQVTS 1294
             ++ +++L   +    + ++  ++ +   + K+ + +D +    ++   ++ +  +++TS
Sbjct: 1286 QDVHEENLRHAKNVTTELQNSYKM-IEQLKIKHTEDMDMLNRRLEDVIEELELKSQEITS 1344

Query: 1295 LQNKLQDKEEHL-RNLQEKY-ADVINQIEILRSEI-EDEKVAFXXXXXXXXXXXXXXXXD 1351
            +QN+L++K   + +++ E+    +  Q+  L +++ E E  A                  
Sbjct: 1345 MQNELEEKTALVSKSMSEEVKLGLETQLAELSTKLTEAEDKAHAQLEKMKKYAAVAKKKT 1404

Query: 1352 LRTENQSYKQMQEQSILNINEENAQLK-KSSXXXXXXXXXXXXRV--NDAEAKVLELTHQ 1408
             + E    K  + +  LN+ +   +L+ +              R+   D E + +++   
Sbjct: 1405 AQCEELETKLRELEESLNLEKIEKELRNRELHEAIAGHQEKDNRIVEMDEELRRIQVERD 1464

Query: 1409 LELKDSE-IYQKTHEYTITLTQRNDEFE------------NVRQQLVEYEKRIEDLTY-- 1453
              +++ E I Q+  + T  L+  N+E +             VR Q++E E  I+ L    
Sbjct: 1465 EAVQNVEAIKQELRQATDKLSTMNEEMQELSEAKDNARELGVRMQVIEAE-YIDQLAQIN 1523

Query: 1454 EKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALE 1513
               +E  IL  K  +     E ++KESE  R +L +    K  E     +   +  +   
Sbjct: 1524 SLRAENGILLSKQTQINERLENVEKESEERRAQLEKYEKQKEIEETQRAEAAVQQAQTCG 1583

Query: 1514 EEVAKTNEMQTALENQEIEIVTLNDEITN-LQNMVR 1548
            E  +K   ++  L+ ++ EI  L++E+ N + N+V+
Sbjct: 1584 ECASKVQALEAKLQERDAEIENLDNELHNSIGNLVQ 1619



 Score =  137 bits (331), Expect = 3e-30
 Identities = 254/1255 (20%), Positives = 534/1255 (42%), Gaps = 134/1255 (10%)

Query: 476  NEIAKVQEQLKQELNDEIKDVNVK--DLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNH 533
            NEI + +  + Q L +++  +N +  DL       E ++  L+D+  A+N+ +++ +S +
Sbjct: 1888 NEIQETRATIDQ-LTEQLTSLNAQREDLARLASDREAELKALHDQFAASNQAILQSRSEY 1946

Query: 534  KL---KLKQMQKTIDNFSKVSDSNKEIVR-LTEELHHLSQ--KVAELEEEKGNLQ----- 582
            +    KL+Q+Q      S   +  K  V  L  EL       ++AELE     +      
Sbjct: 1947 EQLVGKLEQLQSANHELSAAEEVYKNRVHELETELRTSGDNARIAELENRLARITSERDI 2006

Query: 583  LHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQ-QKYDEVE 641
            L L   DS R  E     K   M+ L + + +  +L++ +K  L QEL  L+  K + V 
Sbjct: 2007 LQLQVNDSTRAFED---LKEESMQGLKQLQARIETLIQ-EKNQLTQELETLRVAKPEAVS 2062

Query: 642  DKL--ADISQLQSDQVCSEIKSVHL-----EEQIDALSASKKELALVIENLKLDKEQLYG 694
            ++   A  + +       ++++  +     E+  D    S K +   +E   +D   +  
Sbjct: 2063 EQFVQAATAPVAETVPAPKLEAAAMGDSMWEDDEDPWGLSDKTIPHSVEQ-HVDIPMVLS 2121

Query: 695  TIKDLENDKEDIMNKLQNYIQENMDLTD--KLEKMS----AEKISELLAKINH-EEQSKI 747
                L+   +++  KL+   +EN  L +  K+ ++      +K+ E   + +  + Q K 
Sbjct: 2122 AETQLKLQVDELEEKLRELTEENAKLIEEGKVAQVKNVKYVKKLKEYKVQFDSLQRQLKS 2181

Query: 748  QTQFG----IDAKIQER-DLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQL 802
            Q   G    +D+ I+E     ++ +E  L++ K+   ++      + +R   L    ++ 
Sbjct: 2182 QKSMGGFGDLDSAIEEELKSQVDALEKALTESKAETKKIAAEKEKLLNRIDVLTAATERF 2241

Query: 803  GSYLQEKQKAYSEYTIQEDELVNRLAVL------MDHDRVVEKQLLE----IEHENKELQ 852
                +++      + ++  EL  +L  L       D      ++  E     E E KEL+
Sbjct: 2242 TEAKEKQDTEVHIWQMRYKELEMKLQQLDFGPETKDSTTSPPQERAERDPKYEEELKELK 2301

Query: 853  KKNQILLEENQNLQISLSDMQQHYNALVEKANR-TDLAESESTKYQTQLRDLESNLKRIT 911
               + L  EN+ LQ  L + +      VE++++ T+  E+++ +  +    L+ + + + 
Sbjct: 2302 DSVEALAAENEELQQLLEENRTKRQTSVEESSKKTNELEAKNVELLSNNEKLKGDYETLR 2361

Query: 912  HEHQTLIVQKKKEIEDLE-----IEFNTQIESAIRDKKV--LNEKYEKNIEYVTQLEAQL 964
             +++  ++    +++ +      I+     +++  DK V  LNE+ +  +E  TQLE ++
Sbjct: 2362 KQYEQSLMDANDQVQSMRQNCELIKAEYVEKTSEHDKTVAELNERLQTVLEEKTQLEGKV 2421

Query: 965  QEYKNNIENLNMNVEELNKMNLELIDKHVQ-----KQQTQSPDYTEQYINEINKLNALLK 1019
            Q  ++ +E +N      ++++ EL++  VQ     K++ Q     +  + E  +  A ++
Sbjct: 2422 QGLESEVERINNATTYTDELS-ELLNARVQEVAGLKEELQRLLQDKTQLEENTR--ATIQ 2478

Query: 1020 QKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNE 1079
            Q  EE+     K +    +    +++ + ++ +   +LE +   + +V+   L  + +  
Sbjct: 2479 QLTEELHDKQDKFDALNTA----IAEKDGEILRQAAELEELRGLVDKVNGLELSIEGYTT 2534

Query: 1080 ELQILVREQDDQIKELKETKLTFEMNIPKTEGMIIS--STIEPMSDDANNVDXXXXXXXX 1137
            ++Q    EQ+++++ L++    +E+ + + E  + S  S ++    +    +        
Sbjct: 2535 QVQ----EQNEELETLRDKLRQYEVALTEKEQQVSSQQSQLQQSLSETQQCNTQVQEQHE 2590

Query: 1138 XXXXLKVQEEE--EFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQ 1195
                L V E    E  Q  S  +     LN+ L E    + Q    +  L     V + +
Sbjct: 2591 LAQRLAVAETHVAELTQRLSEAENHIQNLNSALSEKEAHLAQDGEESRRLQDELQVKEAE 2650

Query: 1196 INQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEH 1255
            + ++KSKLE      +   S V   R  ISS   Q   ++ +         + D ++ ++
Sbjct: 2651 LAEVKSKLEAAVQAQEQAASQV---RKEISSIQQQPSVKVIDELPVFTFGSDNDDKELQN 2707

Query: 1256 ELRVQLSAFESKYEQLLDSVQSSTQEETNKIVT--MEQVTSLQNKLQDKEEHLRNLQEKY 1313
             LR +L A   + E L  ++  S   +T +I+    + + +L N+  + E  + +  ++ 
Sbjct: 2708 -LRAELRAKNEEIEHLQYAINES---QTTRIIQELQDNINALYNEKAELESQVISKNQEI 2763

Query: 1314 ADVINQIEILRSE--------IEDEKVAFXXXXXXXXXXXXXXXXD-LRTENQSY-KQMQ 1363
              +  Q++ LRS          ED++  F                  + TE +S  ++  
Sbjct: 2764 NGLKFQLDELRSHQHQPVKRSAEDQEELFKLQNELHIRDQELNELRYVVTEKESQLREAL 2823

Query: 1364 EQSILNINEENA--QLKKSSXXXXXXXXXXXXRVNDAEAKVLELT-------------HQ 1408
            EQ+  N  +  +  +LK                V+D +++V  L               +
Sbjct: 2824 EQASGNAEQHESVEKLKSDLYEKQQELENLKFTVSDLQSEVANLRGLERLAGEDRATIER 2883

Query: 1409 LELKDSEIYQKTHEYTI-TLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMH 1467
            L  +  E+ ++  E     L ++  E +N++QQL    + + +    +E ++  L+L++ 
Sbjct: 2884 LSSEKEEVRREAQEAVERVLREKEQEIDNLKQQLAAENQSLMEALGLRERDIENLKLQIE 2943

Query: 1468 ENANHYETM---------QKESEI-ERVKLIEELNV-KITESVSLNKQVAELNKALEEEV 1516
            +     ++            E+E+ ER + + EL++ K TE  ++  Q++E N   EE V
Sbjct: 2944 QTGLDRDSQLDQRADQVAHLEAELSERDRRLAELSITKDTEIHNIRVQLSEKNARFEELV 3003

Query: 1517 AKT-------NEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRD 1569
            A T       +EM+  LE +E +I  L  ++             +Q+HV+ +  + +   
Sbjct: 3004 ALTEEEERQLSEMRKLLEVKEQQINGLTQQLDEKSKEYELMQHALQRHVTKSDQSTEITQ 3063

Query: 1570 EQLDNTMNKEL-LDAVPRA---ELDLAMYMLHQRDVRCXXXXXXXXXXXXXRDTL 1620
            +QL+ + +    +DA   +   ELDLA+YMLHQRDVRC             RDTL
Sbjct: 3064 QQLEQSASSAAAMDAASSSSANELDLALYMLHQRDVRCEELTHELMQLLEERDTL 3118



 Score =  113 bits (273), Expect = 3e-23
 Identities = 271/1426 (19%), Positives = 573/1426 (40%), Gaps = 136/1426 (9%)

Query: 223  ENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXX 282
            E  I   A  +++K  L++++ +    +SSLE  N   E  R    ++   L +E+E   
Sbjct: 597  ETHIEAIAILENQKLDLMQELHAVKQEVSSLEAENAESENLRVTAEMKVVDLEEEIESLH 656

Query: 283  XXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTN 342
                          +   +   E  T+  E+ S +++ + EL    E+    +     +N
Sbjct: 657  KQQQAEPLTDA--ERIEFQRQIENLTQENERLSQKVSKLEELKSSSEVGSTESFVKTGSN 714

Query: 343  KELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKI 402
             +          ++       K     ++R++G     K+     + SS+T + ++ ++I
Sbjct: 715  VDSTESFEAFAADADKADLLRKIDG--LTRENGA-LLEKLTRFEEKGSSDTGSTESFERI 771

Query: 403  NKN--EIAKLEMVIQSLNKDLVDKEYVISEK---DTXXXXXXXXXXGKDTLIAQL-QLEH 456
             ++    ++LE + +  N +LV K   + EK                 + L+A+L QLE 
Sbjct: 772  PEHGESTSRLENLTRE-NYELVVKLTKLEEKLAASEADTKLQEVLQENERLVAKLKQLEE 830

Query: 457  QQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEI-KDVNVKDL-------------I 502
               +E   ++    + E V E+ + QE   +E + E   +V V+               I
Sbjct: 831  NAVVE--EVVREKRSVE-VEEVPRTQEPEIEETSSEAPTEVLVESTESPPHIVDELVAKI 887

Query: 503  EKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTE 562
            E+LKS+ E I +  +E+ A  K    V    +++   +          +  +     L  
Sbjct: 888  EELKSSLEAIGREKEELAAKLKEKEPVAQELQVEETIVPAEASVVKSSAQQDPSEAELKS 947

Query: 563  ELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQ 622
            +    S+ +A LE E       + +    + +  D+  K+ + E   E   K+  L  S+
Sbjct: 948  DAVQ-SEAIAALEREIERCTALIAEQ---KAVIEDLKTKLADKEE--ELERKSAQLASSE 1001

Query: 623  KFDLVQ-ELHILQQKYDEVEDKLAD----ISQLQSDQVCSEIKSVHLEEQIDALSASKKE 677
              D  Q + H+L+++ +E   ++A+     ++++      E    H+EE   AL    K 
Sbjct: 1002 SHDQDQLDAHVLRRELEESASEIAEWKHKCAEMEEKMKVLEKGRQHIEEGFQALQTENKN 1061

Query: 678  LALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLA 737
            L    E+  +   QL   +    +D E         I     L ++L K   EK  EL  
Sbjct: 1062 LLEQSEHKDVMLSQLKEELDHTISDFEAKSRAQGEVIASQEQLVEELRKNVEEKDLELQG 1121

Query: 738  KINHEE-----QSKIQTQFG-IDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDR 791
            K +  +       ++Q +   ++A++Q+RD  I ++  E+   ++    +EE + +   +
Sbjct: 1122 KYSQLQNDLIKMDELQDKLARLEAQVQQRDATIASLTEEVETLRTNASVVEEDLFMARHQ 1181

Query: 792  RYSLERKADQLGSYLQEKQ--KAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENK 849
               L  K     S  +  Q  +  ++ T+  +EL  +L+  +     ++ Q+  +  EN 
Sbjct: 1182 LTDLHEKLKDSKSLEEYNQLMEQLNDKTMLVEELETKLSQKLAEVNALKAQVESLVSENH 1241

Query: 850  ELQKKNQI-------LLEENQNLQISLSDMQQH----YNAL--VEKANRTDL--AESEST 894
            +L+++ Q+       LL++N N + +L   ++      N L  ++  +  +L  A++ +T
Sbjct: 1242 QLREQFQVDERRIADLLDDNHNQEEALRSSERAKADVENRLLDLQDVHEENLRHAKNVTT 1301

Query: 895  KYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFN--TQIESAIRDKKVLNEKYEK 952
            + Q   + +E    + T +   L  + +  IE+LE++    T +++ + +K  L  K   
Sbjct: 1302 ELQNSYKMIEQLKIKHTEDMDMLNRRLEDVIEELELKSQEITSMQNELEEKTALVSK-SM 1360

Query: 953  NIEYVTQLEAQLQEYKNNI----ENLNMNVEELNKMNLELIDKHVQKQQTQSP-DYTEQY 1007
            + E    LE QL E    +    +  +  +E++ K       K  Q ++ ++     E+ 
Sbjct: 1361 SEEVKLGLETQLAELSTKLTEAEDKAHAQLEKMKKYAAVAKKKTAQCEELETKLRELEES 1420

Query: 1008 IN-----------EINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYES---KLAQF 1053
            +N           E+++  A  ++KD  I+ +++++   QV     V + E+   +L Q 
Sbjct: 1421 LNLEKIEKELRNRELHEAIAGHQEKDNRIVEMDEELRRIQVERDEAVQNVEAIKQELRQA 1480

Query: 1054 TTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMI 1113
            T KL  M EEMQ +S+   ++++    +Q++  E  DQ+ ++         N  + E  I
Sbjct: 1481 TDKLSTMNEEMQELSEAKDNARELGVRMQVIEAEYIDQLAQI---------NSLRAENGI 1531

Query: 1114 ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYT 1173
            + S    +++   NV+             + Q+E E  Q      +Q+        EC +
Sbjct: 1532 LLSKQTQINERLENVEKESEERRAQLEKYEKQKEIEETQRAEAAVQQAQTCG----ECAS 1587

Query: 1174 KIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNL-LSTV-AELRSSISSAVDQR 1231
            K+   + L  +L   D   +   N+L + +  L    +NL LST+ A   +S+  + ++ 
Sbjct: 1588 KV---QALEAKLQERDAEIENLDNELHNSIGNLVQMQENLRLSTIPAAPDASMQESYNEL 1644

Query: 1232 GFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQ 1291
              +   L   +  + +A ++ T HE   +L    ++ ++L  ++Q   +    ++   ++
Sbjct: 1645 MLQYNVLTATN-EEMKAKYEATLHE-NEELLERVARLQELNVTMQERIESVERELARDKE 1702

Query: 1292 VTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIED---EKVAFXXXXXXXXXXXXXX 1348
            V +      +  +  + L+EKY    +++E  +S++ +      A               
Sbjct: 1703 VAA---SFDETHQQYQELREKYEQQRSELETAQSKLREAIASSEASERNLQSTIELLQHE 1759

Query: 1349 XXDLRTENQSYKQMQEQSIL------------NINEENAQLKKSSXXXXXXXXXXXXRVN 1396
               L  EN++ K +++ +IL             IN E AQ +                V+
Sbjct: 1760 KEQLEEENKNLKIVKDNNILLDDSWGDDASSSMINVE-AQPQIRPEPVTETMERHKREVD 1818

Query: 1397 DAEAKVLELTHQLELKDSEIY---------QKTHEYTITLTQRNDEFENVRQQLVEYEKR 1447
             A   V E + Q  L D+ I+          K  +    +    DE   +R QL +    
Sbjct: 1819 QAAVPVSEESSQPPLFDASIFGASPPQPSSSKNAQLEFEMGLLRDEVSVLRNQLDQARSA 1878

Query: 1448 IEDLTYEKESELAILRLKMHENANHYETMQKESE-IERVKLIEELNVKI--TESVSLNKQ 1504
             E++     +E+   R  + +      ++  + E + R+    E  +K    +  + N+ 
Sbjct: 1879 TEEVQARMGNEIQETRATIDQLTEQLTSLNAQREDLARLASDREAELKALHDQFAASNQA 1938

Query: 1505 VAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRAS 1550
            + +     E+ V K  ++Q+A            + +  L+  +R S
Sbjct: 1939 ILQSRSEYEQLVGKLEQLQSANHELSAAEEVYKNRVHELETELRTS 1984



 Score =  104 bits (249), Expect = 2e-20
 Identities = 291/1593 (18%), Positives = 653/1593 (40%), Gaps = 159/1593 (9%)

Query: 73   EHRKATAELLGRPFVPGISESLANTLKQKEILMEKIKQYKELSKRSSTTIVRXXXXXXXX 132
            E  K++ E +GR       E LA  LK+KE + +++ Q +E    +  ++V+        
Sbjct: 888  EELKSSLEAIGRE-----KEELAAKLKEKEPVAQEL-QVEETIVPAEASVVKSSAQQDPS 941

Query: 133  XXXXXXXQLGDVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNK- 191
                   +L      S  I   +  +      +   +  I DL+ K+ +K++ +E K+  
Sbjct: 942  EA-----ELKSDAVQSEAIAALEREIERCTALIAEQKAVIEDLKTKLADKEEELERKSAQ 996

Query: 192  -ATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWK---DEKQRLLKDIESKD 247
             A++                 E++  ++ + +     ME + K     +Q + +  ++  
Sbjct: 997  LASSESHDQDQLDAHVLRRELEESASEIAEWKHKCAEMEEKMKVLEKGRQHIEEGFQALQ 1056

Query: 248  VRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEK 307
                +L E ++  +    ++  E      + E               L ++ +  + EEK
Sbjct: 1057 TENKNLLEQSEHKDVMLSQLKEELDHTISDFEAKSRAQGEVIASQEQLVEE-LRKNVEEK 1115

Query: 308  T-EIEEKGSL---EIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPS 363
              E++ K S    ++  M EL  K+  LE    Q   T   L  ++ T+ T +  V    
Sbjct: 1116 DLELQGKYSQLQNDLIKMDELQDKLARLEAQVQQRDATIASLTEEVETLRTNASVVEEDL 1175

Query: 364  KKGSPLISRKSGRNTASKMKSPWSQLSSET-----LNQDTDKKINKN--EIAKLEMVIQS 416
                  ++    +   SK    ++QL  +      L ++ + K+++   E+  L+  ++S
Sbjct: 1176 FMARHQLTDLHEKLKDSKSLEEYNQLMEQLNDKTMLVEELETKLSQKLAEVNALKAQVES 1235

Query: 417  LNKD--LVDKEYVISEK---DTXXXXXXXXXXGKDTLIAQLQLEHQ----QHMEGPSLIH 467
            L  +   + +++ + E+   D            + +  A+  +E++    Q +   +L H
Sbjct: 1236 LVSENHQLREQFQVDERRIADLLDDNHNQEEALRSSERAKADVENRLLDLQDVHEENLRH 1295

Query: 468  VGTNTEDVNEIAKVQEQLKQELNDEIKDVN--VKDLIEKLKSAEEQITQLNDEIDAANKN 525
                T ++    K+ EQLK +  +++  +N  ++D+IE+L+   ++IT + +E++     
Sbjct: 1296 AKNVTTELQNSYKMIEQLKIKHTEDMDMLNRRLEDVIEELELKSQEITSMQNELEEKTAL 1355

Query: 526  MIKVKSNH-KLKLK-QMQKTIDNFSKVSD-SNKEIVRLTEELHHLSQKVAELEEEKGNLQ 582
            + K  S   KL L+ Q+ +     ++  D ++ ++ ++ +      +K A+ EE +  L+
Sbjct: 1356 VSKSMSEEVKLGLETQLAELSTKLTEAEDKAHAQLEKMKKYAAVAKKKTAQCEELETKLR 1415

Query: 583  LHLVDYDSGRMIESDVYKKMI--------EMENLAETRLKAISLLESQKFDLVQELHILQ 634
              L +  +   IE ++  + +        E +N      + +  ++ ++ + VQ +  ++
Sbjct: 1416 -ELEESLNLEKIEKELRNRELHEAIAGHQEKDNRIVEMDEELRRIQVERDEAVQNVEAIK 1474

Query: 635  QKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLK------LD 688
            Q+  +  DKL+ +++   +   ++  +  L  ++  + A   +    I +L+      L 
Sbjct: 1475 QELRQATDKLSTMNEEMQELSEAKDNARELGVRMQVIEAEYIDQLAQINSLRAENGILLS 1534

Query: 689  KE-QLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKI 747
            K+ Q+   ++++E + E+   +L+ Y ++      ++E+    + +   A+   E  SK+
Sbjct: 1535 KQTQINERLENVEKESEERRAQLEKYEKQK-----EIEETQRAEAAVQQAQTCGECASKV 1589

Query: 748  QTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESI----------AVMEDRRYSLER 797
            Q    ++AK+QERD  IEN+++EL      + +++E++          A M++    L  
Sbjct: 1590 QA---LEAKLQERDAEIENLDNELHNSIGNLVQMQENLRLSTIPAAPDASMQESYNELML 1646

Query: 798  KADQLGSYLQEKQKAYSEYTIQE-DELVNRLAVLMDHDRVVEKQLLEIEHE---NKELQK 853
            + + L +   E+ KA  E T+ E +EL+ R+A L + +  +++++  +E E   +KE+  
Sbjct: 1647 QYNVL-TATNEEMKAKYEATLHENEELLERVARLQELNVTMQERIESVERELARDKEVAA 1705

Query: 854  KNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHE 913
                  ++ Q L+      +        K  R  +A SE+++     R+L+S ++ + HE
Sbjct: 1706 SFDETHQQYQELREKYEQQRSELETAQSKL-REAIASSEASE-----RNLQSTIELLQHE 1759

Query: 914  HQTLIVQKK--KEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNI 971
             + L  + K  K ++D  I  +           ++N + +  I      E  ++ +K  +
Sbjct: 1760 KEQLEEENKNLKIVKDNNILLDDSWGDD-ASSSMINVEAQPQIRPEPVTET-MERHKREV 1817

Query: 972  ENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQK 1031
            +   + V E       L D  +       P  ++    E      LL+   +E+  L  +
Sbjct: 1818 DQAAVPVSE-ESSQPPLFDASIFGASPPQPSSSKNAQLEFEM--GLLR---DEVSVLRNQ 1871

Query: 1032 INNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQ 1091
            ++ A+ +   + +   +++ +    ++ + E++  ++ Q  D  +   + +  ++   DQ
Sbjct: 1872 LDQARSATEEVQARMGNEIQETRATIDQLTEQLTSLNAQREDLARLASDREAELKALHDQ 1931

Query: 1092 I----KELKETKLTFEMNIPKTEGMIISSTIEPMSDDA--NNVDXXXXXXXXXXXXLKVQ 1145
                 + + +++  +E  + K E +  ++     +++   N V              ++ 
Sbjct: 1932 FAASNQAILQSRSEYEQLVGKLEQLQSANHELSAAEEVYKNRVHELETELRTSGDNARIA 1991

Query: 1146 EEE----EFIQERSVLQEQSAKLNTELQECYTKIIQ-LETLNTELTGHDVVNQEQINQLK 1200
            E E        ER +LQ Q        ++   + +Q L+ L   +   + + QE+ NQL 
Sbjct: 1992 ELENRLARITSERDILQLQVNDSTRAFEDLKEESMQGLKQLQARI---ETLIQEK-NQLT 2047

Query: 1201 SKLEQLNTENDNLLST--VAELRSSISSAVDQRGFEIA----ELWKQ------------- 1241
             +LE L       +S   V    + ++  V     E A     +W+              
Sbjct: 2048 QELETLRVAKPEAVSEQFVQAATAPVAETVPAPKLEAAAMGDSMWEDDEDPWGLSDKTIP 2107

Query: 1242 HLAQREADFQ---KTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNK 1298
            H  ++  D       E +L++Q+   E K  +L +  +++   E  K+  ++ V  ++ K
Sbjct: 2108 HSVEQHVDIPMVLSAETQLKLQVDELEEKLRELTE--ENAKLIEEGKVAQVKNVKYVK-K 2164

Query: 1299 LQDKEEHLRNLQE--KYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTEN 1356
            L++ +    +LQ   K    +     L S IE+E  +                  +  E 
Sbjct: 2165 LKEYKVQFDSLQRQLKSQKSMGGFGDLDSAIEEELKSQVDALEKALTESKAETKKIAAEK 2224

Query: 1357 QSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDS-- 1414
            +  K +    +L    E  +  ++             R  + E K+ +L    E KDS  
Sbjct: 2225 E--KLLNRIDVLTAATE--RFTEAKEKQDTEVHIWQMRYKELEMKLQQLDFGPETKDSTT 2280

Query: 1415 ----EIYQKTHEYTITLTQRNDEFENVR------QQLVEYEKRIEDLTYEKESELA-ILR 1463
                E  ++  +Y   L +  D  E +       QQL+E  +     + E+ S+    L 
Sbjct: 2281 SPPQERAERDPKYEEELKELKDSVEALAAENEELQQLLEENRTKRQTSVEESSKKTNELE 2340

Query: 1464 LKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQ 1523
             K  E  ++ E ++ + E  R K  E+  +   + V   +Q  EL KA  E V KT+E  
Sbjct: 2341 AKNVELLSNNEKLKGDYETLR-KQYEQSLMDANDQVQSMRQNCELIKA--EYVEKTSEHD 2397

Query: 1524 TALENQEIEIVTLNDEITNLQNMVRASSSKIQK 1556
              +      + T+ +E T L+  V+   S++++
Sbjct: 2398 KTVAELNERLQTVLEEKTQLEGKVQGLESEVER 2430



 Score =  103 bits (246), Expect = 5e-20
 Identities = 232/1188 (19%), Positives = 479/1188 (40%), Gaps = 110/1188 (9%)

Query: 461  EGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEID 520
            E P  +  G   E V  + +  EQ K +L + +KD+ +++  + LK  EE++ +  +++ 
Sbjct: 7    EPPGTMEAGP-PESVANLKETCEQSKNQL-ESVKDIMLRNK-QSLKKKEEELEEYANKLS 63

Query: 521  AAN---------KNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKV 571
                        K+     S    K K    T +    V D   +      +   L +K+
Sbjct: 64   KFKTRAKASRTPKDDAASSSESTPKSKSDTSTAEPSDDVVDDISQAKTPKAKSSLLQKKL 123

Query: 572  AELEEEKGNLQLHLVDYDSGRMIESDV--YKKMIEMENLAETRLKAISLLESQKFDLVQE 629
            AE  +        L +  S R +E  V   ++ +E   +A   + +  L+ SQ    V E
Sbjct: 124  AEDRKIFEQRSKELTE--SKRAVEEKVEALRQQLEERYVAPVSVVSPVLVTSQGAHPVME 181

Query: 630  LHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDK 689
            L  +Q K +++ +    I +L++  V  +++  +L+E+   + +  K + L+  +L +  
Sbjct: 182  LSHVQDKDNKITELSNKIFELEA--VIIDLQE-NLKEKDSVIDSKTKAITLMSADLSMKG 238

Query: 690  EQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSA--EKISELLAKINHEEQSKI 747
            +    T+  LE+ K+++ +  +N++     L  K E+++   E +  L  K+  ++Q++ 
Sbjct: 239  KT---TLDTLEDTKDEMRSMQENFVLVESSLKKKAEQIATLEENVQSLTEKLEAQKQAET 295

Query: 748  QTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQ 807
                 + A      +        L+  K  +  ++E+  ++E    SL+ K + L   L+
Sbjct: 296  -----VSADFSRSTM------DTLADTKDAMKSMQENFVLIET---SLKSKNEHLLKQLE 341

Query: 808  EKQKAYSEYTIQEDELVNRLAVLMDHD-RVVEKQLLEIEHENKELQKKNQILLEENQNLQ 866
            E++   +E   +   L   L +    +   +  ++ ++E  N++LQ +   L +    LQ
Sbjct: 342  EREIKLAESEARILNLETGLGIERQPNVEEITYKVDKLEEMNRKLQDEKYELQKNIAELQ 401

Query: 867  ISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIE 926
              +   +   +  + + NR    ES   + +   + LE   K   H     + ++ + + 
Sbjct: 402  DKIISTESRTDESIMEDNRIAELESLIEELKKSNQHLEEEYKAALHNQVAEMNERNETLS 461

Query: 927  DLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNL 986
            +  +E   Q+     DK  L  K       ++ +E +  +    ++ L   +EELNK  +
Sbjct: 462  NKIVELEKQVNDVTNDKIELESK-------LSAIETEAPKEDEQVQKLTKELEELNKSMI 514

Query: 987  ELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVS-------- 1038
            +L  +H  K + ++     +   +++  NA L +   ++  L ++  N Q+S        
Sbjct: 515  KLKAQH--KNKLKNLQKQLENFKKVSDKNAELVKLGNQVALLEEEKGNLQLSLVDFDELK 572

Query: 1039 -----YMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIK 1093
                 +   ++D E K+A    ++E   E +  +  Q LD  Q    ++  V   + +  
Sbjct: 573  ASAGDWKERIADLEGKVASQAKEIETHIEAIAILENQKLDLMQELHAVKQEVSSLEAENA 632

Query: 1094 ELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQE 1153
            E +  ++T EM +   E  I S   +  ++   + +               QE E   Q+
Sbjct: 633  ESENLRVTAEMKVVDLEEEIESLHKQQQAEPLTDAERIEFQRQIENL---TQENERLSQK 689

Query: 1154 RSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNL 1213
             S L+E  +       E + K       +TE       + ++ + L+ K++ L  EN  L
Sbjct: 690  VSKLEELKSSSEVGSTESFVK-TGSNVDSTESFEAFAADADKADLLR-KIDGLTRENGAL 747

Query: 1214 LSTVAELRSSISSAVDQRGFEIAELWKQH--LAQREADFQKTEHELRVQLSAFESKY--- 1268
            L  +       SS  D    E  E   +H     R  +  +  +EL V+L+  E K    
Sbjct: 748  LEKLTRFEEKGSS--DTGSTESFERIPEHGESTSRLENLTRENYELVVKLTKLEEKLAAS 805

Query: 1269 --EQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDK-----EEHLR----NLQEKYADVI 1317
              +  L  V    +    K+  +E+   ++  +++K     EE  R     ++E  ++  
Sbjct: 806  EADTKLQEVLQENERLVAKLKQLEENAVVEEVVREKRSVEVEEVPRTQEPEIEETSSEAP 865

Query: 1318 NQIEILRSE----IEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQM-QEQSI-LNIN 1371
             ++ +  +E    I DE VA                 +L  + +  + + QE  +   I 
Sbjct: 866  TEVLVESTESPPHIVDELVAKIEELKSSLEAIGREKEELAAKLKEKEPVAQELQVEETIV 925

Query: 1372 EENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQK---THEYTITLT 1428
               A + KSS                +EA +  L  ++E   + I ++     +    L 
Sbjct: 926  PAEASVVKSSAQQDPSEAELKSDAVQSEA-IAALEREIERCTALIAEQKAVIEDLKTKLA 984

Query: 1429 QRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHY-ETMQKESEI-ERVK 1486
             + +E E    QL   E   +D     + +  +LR ++ E+A+   E   K +E+ E++K
Sbjct: 985  DKEEELERKSAQLASSESHDQD-----QLDAHVLRRELEESASEIAEWKHKCAEMEEKMK 1039

Query: 1487 LIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNM 1546
            ++E+    I E     + +   NK L E+    + M + L+ +    ++  +  +  Q  
Sbjct: 1040 VLEKGRQHIEEGF---QALQTENKNLLEQSEHKDVMLSQLKEELDHTISDFEAKSRAQGE 1096

Query: 1547 VRASS----SKIQKHVSFASDTKQGRDEQLDNTMNK--ELLDAVPRAE 1588
            V AS      +++K+V       QG+  QL N + K  EL D + R E
Sbjct: 1097 VIASQEQLVEELRKNVEEKDLELQGKYSQLQNDLIKMDELQDKLARLE 1144



 Score = 97.9 bits (233), Expect = 2e-18
 Identities = 167/851 (19%), Positives = 375/851 (44%), Gaps = 91/851 (10%)

Query: 481  VQEQLKQELNDEIKDVNVKDLIEKLKSA--------EEQITQLNDEIDAANKNMIKVKSN 532
            V+E  K+    E K+V +    EKLK          E+ +   ND++ +  +N   +K+ 
Sbjct: 2329 VEESSKKTNELEAKNVELLSNNEKLKGDYETLRKQYEQSLMDANDQVQSMRQNCELIKAE 2388

Query: 533  HKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDS-G 591
            +      ++KT ++   V++ N+ +  + EE   L  KV  LE E   +       D   
Sbjct: 2389 Y------VEKTSEHDKTVAELNERLQTVLEEKTQLEGKVQGLESEVERINNATTYTDELS 2442

Query: 592  RMIES---DVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLA--D 646
             ++ +   +V     E++ L + + +      +    L +ELH  Q K+D +   +A  D
Sbjct: 2443 ELLNARVQEVAGLKEELQRLLQDKTQLEENTRATIQQLTEELHDKQDKFDALNTAIAEKD 2502

Query: 647  ISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLE---NDK 703
               L+      E++   L ++++ L  S +     ++    + E L   ++  E    +K
Sbjct: 2503 GEILRQAAELEELRG--LVDKVNGLELSIEGYTTQVQEQNEELETLRDKLRQYEVALTEK 2560

Query: 704  EDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLY 763
            E  ++  Q+ +Q+++  T +      E+  EL  ++   E    +    +  ++ E + +
Sbjct: 2561 EQQVSSQQSQLQQSLSETQQCNTQVQEQ-HELAQRLAVAETHVAE----LTQRLSEAENH 2615

Query: 764  IENIESELSKYKSRICRLEESIAVMED----RRYSLERKADQLGSYLQEKQKAYSEY--- 816
            I+N+ S LS+ ++ + +  E    ++D    +   L     +L + +Q +++A S+    
Sbjct: 2616 IQNLNSALSEKEAHLAQDGEESRRLQDELQVKEAELAEVKSKLEAAVQAQEQAASQVRKE 2675

Query: 817  --TIQED---ELVNRLAVLM----DHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQI 867
              +IQ+    ++++ L V      + D+ ++    E+  +N+E++   Q  + E+Q  +I
Sbjct: 2676 ISSIQQQPSVKVIDELPVFTFGSDNDDKELQNLRAELRAKNEEIEHL-QYAINESQTTRI 2734

Query: 868  SLSDMQQHYNALV-EKANRTDLAESESTKYQTQLRDLESNLKRI-THEHQTLIVQKKKEI 925
             + ++Q + NAL  EKA      ES+      ++  L+  L  + +H+HQ +    K+  
Sbjct: 2735 -IQELQDNINALYNEKAE----LESQVISKNQEINGLKFQLDELRSHQHQPV----KRSA 2785

Query: 926  EDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMN 985
            ED E  F  Q E  IRD+++   +Y      VT+ E+QL+E    +E  + N E+   + 
Sbjct: 2786 EDQEELFKLQNELHIRDQELNELRY-----VVTEKESQLRE---ALEQASGNAEQHESVE 2837

Query: 986  LELIDKHVQKQQTQSPDYTEQYI-NEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVS 1044
                D + ++Q+ ++  +T   + +E+  L  L +   E+   + +  +  +        
Sbjct: 2838 KLKSDLYEKQQELENLKFTVSDLQSEVANLRGLERLAGEDRATIERLSSEKEEVRREAQE 2897

Query: 1045 DYESKLAQFTTKLENMEEEMQRVSKQLLDS----KQHNEELQILVR----EQDDQIKELK 1096
              E  L +   +++N+++++   ++ L+++    ++  E L++ +     ++D Q+ +  
Sbjct: 2898 AVERVLREKEQEIDNLKQQLAAENQSLMEALGLRERDIENLKLQIEQTGLDRDSQLDQRA 2957

Query: 1097 ETKLTFEMNIPKTEGMIISSTIEPMSDDAN-NVDXXXXXXXXXXXXLKVQEEEEFIQE-R 1154
            +     E  + + +  +   +I   ++  N  V                +EEE  + E R
Sbjct: 2958 DQVAHLEAELSERDRRLAELSITKDTEIHNIRVQLSEKNARFEELVALTEEEERQLSEMR 3017

Query: 1155 SVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLL 1214
             +L+ +  ++N   Q+   K  + E +   L  H   + +     + +LEQ         
Sbjct: 3018 KLLEVKEQQINGLTQQLDEKSKEYELMQHALQRHVTKSDQSTEITQQQLEQ-------SA 3070

Query: 1215 STVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDS 1274
            S+ A + ++ SS+ ++   ++A L+  H  QR+   ++  HEL   L   ++   +L ++
Sbjct: 3071 SSAAAMDAASSSSANE--LDLA-LYMLH--QRDVRCEELTHELMQLLEERDTLQLRLSNA 3125

Query: 1275 VQSSTQEETNK 1285
            ++    EE  K
Sbjct: 3126 IR--VNEELRK 3134



 Score = 90.6 bits (215), Expect = 3e-16
 Identities = 283/1586 (17%), Positives = 623/1586 (39%), Gaps = 119/1586 (7%)

Query: 62   ENAALVSKRIKEHRKATAELLGRPFVPGISESLANTLKQKEILMEKIKQYKELSKRSST- 120
            E  ALVSK + E  K   E      +  +S  L     +    +EK+K+Y  ++K+ +  
Sbjct: 1351 EKTALVSKSMSEEVKLGLETQ----LAELSTKLTEAEDKAHAQLEKMKKYAAVAKKKTAQ 1406

Query: 121  -----TIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNALSVLQVKMKIMETTILDL 175
                 T +R               +  ++       +EKDN +  +  +++ ++   ++ 
Sbjct: 1407 CEELETKLRELEESLNLEKIEKELRNRELHEAIAGHQEKDNRIVEMDEELRRIQ---VER 1463

Query: 176  QEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDE 235
             E +   + I +   +AT                  ++ ++   +MQ     +EAE+ D+
Sbjct: 1464 DEAVQNVEAIKQELRQATDKLSTMNEEMQELSEAK-DNARELGVRMQ----VIEAEYIDQ 1518

Query: 236  KQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXL 295
              ++        + +S   + N+ LE     +  E  +   +LE+               
Sbjct: 1519 LAQINSLRAENGILLSKQTQINERLE----NVEKESEERRAQLEKYEKQKEIEETQRAEA 1574

Query: 296  AKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEH-LNCQIRQTNKELEN-KLATMG 353
            A Q  +   E  ++++   +LE A + E   +IE L++ L+  I    +  EN +L+T+ 
Sbjct: 1575 AVQQAQTCGECASKVQ---ALE-AKLQERDAEIENLDNELHNSIGNLVQMQENLRLSTIP 1630

Query: 354  TESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMV 413
                A S        ++       T  +MK+ +     E  N++  +++ + +   + M 
Sbjct: 1631 AAPDA-SMQESYNELMLQYNVLTATNEEMKAKYEATLHE--NEELLERVARLQELNVTMQ 1687

Query: 414  --IQSLNKDLV-DKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGT 470
              I+S+ ++L  DKE   S  +T           +     + +LE  Q     ++     
Sbjct: 1688 ERIESVERELARDKEVAASFDETHQQYQELREKYEQQ---RSELETAQSKLREAIASSEA 1744

Query: 471  NTEDVNEIAKVQEQLKQELNDEIKDVN-VKD---LIEKLKSAEEQITQLNDEIDAANKN- 525
            +  ++    ++ +  K++L +E K++  VKD   L++     +   + +N E     +  
Sbjct: 1745 SERNLQSTIELLQHEKEQLEEENKNLKIVKDNNILLDDSWGDDASSSMINVEAQPQIRPE 1804

Query: 526  -MIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLH 584
             + +    HK ++ Q    +   S         +         S K A+LE E G L+  
Sbjct: 1805 PVTETMERHKREVDQAAVPVSEESSQPPLFDASIFGASPPQPSSSKNAQLEFEMGLLRDE 1864

Query: 585  LV----DYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYD-E 639
            +       D  R    +V  +M     + ETR     L E       Q   + +   D E
Sbjct: 1865 VSVLRNQLDQARSATEEVQARM--GNEIQETRATIDQLTEQLTSLNAQREDLARLASDRE 1922

Query: 640  VEDKLADISQLQSDQVCSEIKSVH--LEEQIDALSASKKELALVIENLKLDKEQLYGTIK 697
             E K        S+Q   + +S +  L  +++ L ++  EL+   E  K    +L   ++
Sbjct: 1923 AELKALHDQFAASNQAILQSRSEYEQLVGKLEQLQSANHELSAAEEVYKNRVHELETELR 1982

Query: 698  DLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKI-QTQFGIDAK 756
                D   I  +L+N +       D L+ +     +     +  E    + Q Q  I+  
Sbjct: 1983 T-SGDNARIA-ELENRLARITSERDILQ-LQVNDSTRAFEDLKEESMQGLKQLQARIETL 2039

Query: 757  IQERDLYIENIESELSKYKSRICR--LEESIAVMEDRRYSLERKADQLGSYLQEKQK--- 811
            IQE++   + +E+        +    ++ + A + +   + + +A  +G  + E  +   
Sbjct: 2040 IQEKNQLTQELETLRVAKPEAVSEQFVQAATAPVAETVPAPKLEAAAMGDSMWEDDEDPW 2099

Query: 812  AYSEYTIQED-ELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQI--- 867
              S+ TI    E    + +++  +  ++ Q+ E+E + +EL ++N  L+EE +  Q+   
Sbjct: 2100 GLSDKTIPHSVEQHVDIPMVLSAETQLKLQVDELEEKLRELTEENAKLIEEGKVAQVKNV 2159

Query: 868  ----SLSDMQQHYNALVE--KANRT-----DLAESESTKYQTQLRDLESNLKRITHEHQT 916
                 L + +  +++L    K+ ++     DL  +   + ++Q+  LE  L     E + 
Sbjct: 2160 KYVKKLKEYKVQFDSLQRQLKSQKSMGGFGDLDSAIEEELKSQVDALEKALTESKAETKK 2219

Query: 917  LIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNM 976
            +  +K+K +  +++            +K   E +   + Y  +LE +LQ+     E  + 
Sbjct: 2220 IAAEKEKLLNRIDVLTAATERFTEAKEKQDTEVHIWQMRY-KELEMKLQQLDFGPETKDS 2278

Query: 977  NVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQ----KDEEIIALNQKI 1032
                  +      D   +++  +  D  E    E  +L  LL++    +   +   ++K 
Sbjct: 2279 TTSPPQERAER--DPKYEEELKELKDSVEALAAENEELQQLLEENRTKRQTSVEESSKKT 2336

Query: 1033 NNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNE----ELQILVREQ 1088
            N  +   + ++S+ E     + T  +  E+ +   + Q+   +Q+ E    E      E 
Sbjct: 2337 NELEAKNVELLSNNEKLKGDYETLRKQYEQSLMDANDQVQSMRQNCELIKAEYVEKTSEH 2396

Query: 1089 DDQIKELKETKLTFEMNIPKTEGMI--ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQE 1146
            D  + EL E   T      + EG +  + S +E +++     D            +   +
Sbjct: 2397 DKTVAELNERLQTVLEEKTQLEGKVQGLESEVERINNATTYTDELSELLNARVQEVAGLK 2456

Query: 1147 EE--EFIQERSVLQEQS-AKLNTELQECYTKIIQLETLNTELTGHD--VVNQ----EQIN 1197
            EE    +Q+++ L+E + A +    +E + K  + + LNT +   D  ++ Q    E++ 
Sbjct: 2457 EELQRLLQDKTQLEENTRATIQQLTEELHDKQDKFDALNTAIAEKDGEILRQAAELEELR 2516

Query: 1198 QLKSKLEQLNTENDNLLSTVAELRSSISSAVDQ-RGFEIAELWK-QHLAQREADFQKTEH 1255
             L  K+  L    +   + V E    + +  D+ R +E+A   K Q ++ +++  Q++  
Sbjct: 2517 GLVDKVNGLELSIEGYTTQVQEQNEELETLRDKLRQYEVALTEKEQQVSSQQSQLQQSLS 2576

Query: 1256 ELRVQLSAFESKYE--QLLDSVQSSTQEETNKIVTME-QVTSLQNKLQDKEEHLRNLQEK 1312
            E +   +  + ++E  Q L   ++   E T ++   E  + +L + L +KE HL    E+
Sbjct: 2577 ETQQCNTQVQEQHELAQRLAVAETHVAELTQRLSEAENHIQNLNSALSEKEAHLAQDGEE 2636

Query: 1313 YADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQ--SYKQMQEQSILNI 1370
               + +++++  +E+ + K                   ++ +  Q  S K + E  +   
Sbjct: 2637 SRRLQDELQVKEAELAEVKSKLEAAVQAQEQAASQVRKEISSIQQQPSVKVIDELPVFTF 2696

Query: 1371 NEEN-----AQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTI 1425
              +N       L+                +N  E++   +  +L+   + +Y +  E   
Sbjct: 2697 GSDNDDKELQNLRAELRAKNEEIEHLQYAIN--ESQTTRIIQELQDNINALYNEKAELES 2754

Query: 1426 TLTQRNDEFENVRQQLVEYEK-RIEDLTYEKESELAILRLKMHENANHYETMQKESEIER 1484
             +  +N E   ++ QL E    + + +    E +  + +L   +N  H    Q+ +E+  
Sbjct: 2755 QVISKNQEINGLKFQLDELRSHQHQPVKRSAEDQEELFKL---QNELHIRD-QELNELRY 2810

Query: 1485 VKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQ 1544
            V  + E   ++ E++      AE ++++E+  +   E Q  LEN +  +  L  E+ NL+
Sbjct: 2811 V--VTEKESQLREALEQASGNAEQHESVEKLKSDLYEKQQELENLKFTVSDLQSEVANLR 2868

Query: 1545 NMVRASSSKIQKHVSFASDTKQGRDE 1570
             + R +          +S+ ++ R E
Sbjct: 2869 GLERLAGEDRATIERLSSEKEEVRRE 2894



 Score = 48.0 bits (109), Expect = 0.002
 Identities = 142/746 (19%), Positives = 309/746 (41%), Gaps = 65/746 (8%)

Query: 143  DVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXX 202
            +V  ++N     D    +L  +++ +     +LQ  + +K Q+ E   +AT         
Sbjct: 2427 EVERINNATTYTDELSELLNARVQEVAGLKEELQRLLQDKTQL-EENTRATIQQLTEELH 2485

Query: 203  XXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRI----SSLEEANK 258
                      D        ++  I  +A   +E + L+  +   ++ I    + ++E N+
Sbjct: 2486 DKQDKF----DALNTAIAEKDGEILRQAAELEELRGLVDKVNGLELSIEGYTTQVQEQNE 2541

Query: 259  LLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEI 318
             LE  R ++      L ++ +Q                 Q      +E+ E+ ++ ++  
Sbjct: 2542 ELETLRDKLRQYEVALTEKEQQVSSQQSQLQQSLSET--QQCNTQVQEQHELAQRLAVAE 2599

Query: 319  ANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSK-KGSPLISRKSGRN 377
             ++ ELT+++   E+    +     E E  LA  G ES+ +    + K + L   KS   
Sbjct: 2600 THVAELTQRLSEAENHIQNLNSALSEKEAHLAQDGEESRRLQDELQVKEAELAEVKSKLE 2659

Query: 378  TA-SKMKSPWSQLSSE--TLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTX 434
             A    +   SQ+  E  ++ Q    K+  +E+        + +K+L +    +  K+  
Sbjct: 2660 AAVQAQEQAASQVRKEISSIQQQPSVKV-IDELPVFTFGSDNDDKELQNLRAELRAKNEE 2718

Query: 435  XXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQE--QLKQELNDE 492
                        T   ++  E Q ++   +L +     E    I+K QE   LK +L DE
Sbjct: 2719 IEHLQYAINESQT--TRIIQELQDNIN--ALYNEKAELES-QVISKNQEINGLKFQL-DE 2772

Query: 493  IKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSD 552
            ++  +    +++    +E++ +L +E+   ++ + +++     K  Q+++ ++  S  ++
Sbjct: 2773 LRS-HQHQPVKRSAEDQEELFKLQNELHIRDQELNELRYVVTEKESQLREALEQASGNAE 2831

Query: 553  SNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETR 612
             ++ + +L  +L+   +K  ELE    NL+  + D      ++S+V   +  +E LA   
Sbjct: 2832 QHESVEKLKSDLY---EKQQELE----NLKFTVSD------LQSEV-ANLRGLERLAGED 2877

Query: 613  LKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALS 672
               I  L S+K ++ +E     ++   + +K  +I  L+  Q+ +E +S  L E +    
Sbjct: 2878 RATIERLSSEKEEVRREAQEAVERV--LREKEQEIDNLK-QQLAAENQS--LMEALGLRE 2932

Query: 673  ASKKELALVIENLKLDK----EQLYGTIKDLENDKEDIMNKLQNY-IQENMDLTDKLEKM 727
               + L L IE   LD+    +Q    +  LE +  +   +L    I ++ ++ +   ++
Sbjct: 2933 RDIENLKLQIEQTGLDRDSQLDQRADQVAHLEAELSERDRRLAELSITKDTEIHNIRVQL 2992

Query: 728  SAE--KISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESI 785
            S +  +  EL+A    EE+   + +  ++ K Q+ +   + ++ +  +Y+     L+  +
Sbjct: 2993 SEKNARFEELVALTEEEERQLSEMRKLLEVKEQQINGLTQQLDEKSKEYELMQHALQRHV 3052

Query: 786  AVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIE 845
               +      +++ +Q  S       A S    + D     LA+ M H R V  +  E+ 
Sbjct: 3053 TKSDQSTEITQQQLEQSASSAAAMDAASSSSANELD-----LALYMLHQRDVRCE--ELT 3105

Query: 846  HENKELQKKNQILLEENQNLQISLSD 871
            HE  +       LLEE   LQ+ LS+
Sbjct: 3106 HELMQ-------LLEERDTLQLRLSN 3124


>UniRef50_A2EYA1 Cluster: Viral A-type inclusion protein, putative;
            n=1; Trichomonas vaginalis G3|Rep: Viral A-type inclusion
            protein, putative - Trichomonas vaginalis G3
          Length = 1662

 Score =  197 bits (481), Expect = 2e-48
 Identities = 283/1371 (20%), Positives = 634/1371 (46%), Gaps = 92/1371 (6%)

Query: 213  DTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHS 272
            + +++  ++QE     E  +K + +   K IE    +IS+ +E +K  +A + +++ E  
Sbjct: 196  ELEEKDAEIQELKEQNEGAYKMKYETATKTIELLQKQISASQEISKENDALKSKLA-EKD 254

Query: 273  KLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLE 332
            K  Q                  L+K +I+ S  +  E E+K   EI N+ +  ++++  +
Sbjct: 255  KQLQNYNDMNSLIKEQREQIEKLSK-NIDDS-SDFAENEKKYQNEIQNLKKQIEELQEND 312

Query: 333  HLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSE 392
            +    I  T+ E++ +   +  E + + + +K+   L  +        K K    +  +E
Sbjct: 313  NAWGDIDDTD-EIKQENENLKKEIENLKNQNKEIGNLQLQIEKLKDIIKEK----ESDNE 367

Query: 393  TLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTL---- 448
            +L Q+ +K  N  EI K++   Q+L   + + +  I E ++           K  L    
Sbjct: 368  SLLQELEKSENNFEIEKIKKENQNLQTKVKEMQETIDELESNAWNDDGNDEIKQNLDKLK 427

Query: 449  --IAQLQLEHQ----QHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVK--- 499
              I  L+ E++    Q  E         N +++ EI +  E+L++E N+ +K +N +   
Sbjct: 428  QEINNLKKENENLQKQVEENEENAWNDGNNDEIEEIKQNLEKLQKE-NENLKKINEEKSN 486

Query: 500  -DLIEKLKSAEEQITQLNDEI------DAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSD 552
             D I KLK    ++ + N+E+      +  N++  +  SN K + +++++ I    K  +
Sbjct: 487  DDEINKLKQEISELKKENEELQENLWNENENEDNQEEISNLKKENEKLKQNIKELQKQIE 546

Query: 553  SNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETR 612
            +N+E +   E  + L QKV ELE E  N    L + ++    E++  KK  E+++L E  
Sbjct: 547  TNEENL-WNENENDLKQKVTELESEVKNSD-KLKEENNKLKKENEELKK--EIDDLTENV 602

Query: 613  LKAISLLESQKFD-LVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDAL 671
             K     ++Q+ + L QE++ L+++ +E++ ++ ++ +   ++  +E +S  L++++  L
Sbjct: 603  WKDDE--DNQETEKLKQEINNLKKENEELKKEMDELQESTWNESYTE-ESDELKQKLKEL 659

Query: 672  SASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLE-KMSAE 730
                K+     E+LK   EQ    + +L+ + E I   L+  I+EN + +D  E ++  +
Sbjct: 660  EQKYKDTEKSNEDLKKLLEQ----VDNLQKESEKINQDLEKQIEENQENSDVDENEILKQ 715

Query: 731  KISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMED 790
            K++EL +++  +E+   + +   +   +E +   EN  +E    + +  +LE+   +++ 
Sbjct: 716  KVTELESEVKEKEKLNEELKKENEDLKKEVENLQENAWNETENEEIKE-KLEKENEILQK 774

Query: 791  RRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEK------QLLEI 844
            +     +  + L   L E +   S    + D+L  ++  +    ++  +      Q L++
Sbjct: 775  QVEENNKTLNDLKQKLSESENEKSVKNSENDKLKQKVTEIESDFKISNEKSSNLQQKLDV 834

Query: 845  EHENKE-LQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRD- 902
              +N E L+K+ +I  E+NQ LQ   SD+Q  + +L ++ +   L  +   K +++L + 
Sbjct: 835  LSQNLEKLEKEMKISSEKNQKLQKENSDLQNQFTSLQKQNSDNQLKITSLLKEKSELENQ 894

Query: 903  LESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIE--YVTQL 960
            L  N  +    + +     +KEI DL+ +   Q E      K L E+ +K  +  +    
Sbjct: 895  LNENSTQNLESNSS-----EKEIRDLKEKITKQNEKI----KELEEEVKKGYQDLWGADS 945

Query: 961  EAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQ 1020
            +   +E    I+NL + +E++NK +LE I   V+K++    +  E   N+I K+   L++
Sbjct: 946  DDDSKEKDEEIKNLKLEIEKINKNHLEKIGI-VEKEKKNEIEKRE---NKIKKMRIDLQK 1001

Query: 1021 KDEEIIALNQKIN-NAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNE 1079
            KDEEI  LN++I+ N +  + ++    + +++    + E +++E+    K++ + +Q   
Sbjct: 1002 KDEEINKLNKEISQNKKDEWSTVTFGDDEEISSLKKENERIKQEITEKQKEIEEIQQ--- 1058

Query: 1080 ELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXX 1139
            +L    +E +++  E+   K   E  +   E    +  ++   ++ N+            
Sbjct: 1059 KLSKFTKENEEKSSEISLLKKENEEKLSVLEKE--NEELKQRIEEFNSFKKENEENKQKI 1116

Query: 1140 XXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQ-LETLNTELTGHDVVNQEQINQ 1198
              L  +E ++ + E SVL++++ +L  +L E   ++ Q +   N + +     N+E+++ 
Sbjct: 1117 YNLG-EETKKKLNEISVLKKENEELKQKLNEINEEMKQKIVDFNEKFSNSKKENEEKLSV 1175

Query: 1199 LKSK---LEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQH--LAQREADFQKT 1253
            LK +   L+Q   E ++ +    E +  ++   ++   +++ L K++  + Q  +D  K 
Sbjct: 1176 LKKENDNLKQKLNEFNSFMKESEENKQRLNDLGEETKKKLSILKKENEEMKQNISDLMKE 1235

Query: 1254 EHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKY 1313
              EL  +LS    + E+   + +   + E N    +E+ + L+ + ++ ++ L  + ++ 
Sbjct: 1236 NKELNERLSKSIKENEE---NKKKLNENELNFKQEIEENSLLKKENEENKQKLNEINQEM 1292

Query: 1314 ADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEE 1373
               +N+I  L+ E ED K +                 +   + ++ K+M++  I  + +E
Sbjct: 1293 KKKLNEISNLKRENEDLKRSLNGNEEIIEEMNEINKENDSIKKEN-KEMKQNLIPKLQKE 1351

Query: 1374 NAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDE 1433
            N +L                ++ + +    E++ QL+ +++E  +++      + + ND+
Sbjct: 1352 NEKLNNEISQIQIENEKLKKQIEEMKQISNEIS-QLK-QENEDLKRSLNGNQEINKENDD 1409

Query: 1434 FENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENAN-HYETMQKESEIERVKLIEELN 1492
             +   ++L +  + ++    +K +   +L+    EN        QK+ E E++   EEL 
Sbjct: 1410 LKKENEKLNQKMEEMKKSLVDKSNLNELLKKLQKENEELSISLSQKQKENEKIN--EELT 1467

Query: 1493 VKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNL 1543
             K    + + KQ  +L   L    A  +EM   L+N+  E    N+E++ L
Sbjct: 1468 KK---QIEIEKQ-KDLETNLNNSDANKDEMIELLQNENEETKRNNEELSLL 1514



 Score =  184 bits (449), Expect = 1e-44
 Identities = 273/1379 (19%), Positives = 599/1379 (43%), Gaps = 126/1379 (9%)

Query: 213  DTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHS 272
            +T  +  ++ +  I+   E   E   L   +  KD ++ +  + N L++  R +I  + S
Sbjct: 220  ETATKTIELLQKQISASQEISKENDALKSKLAEKDKQLQNYNDMNSLIKEQREQIE-KLS 278

Query: 273  KLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKT--EIEEKGSLEIANMTELTKKIEL 330
            K   +                 L KQ  E    +    +I++   ++  N   L K+IE 
Sbjct: 279  KNIDDSSDFAENEKKYQNEIQNLKKQIEELQENDNAWGDIDDTDEIKQEN-ENLKKEIEN 337

Query: 331  LEHLNCQIRQTNKELENK---LATMGTESKAVSSPSKKGSPLIS----RKSGRNTASKMK 383
            L++ N +I     ++E     +    ++++++    +K          +K  +N  +K+K
Sbjct: 338  LKNQNKEIGNLQLQIEKLKDIIKEKESDNESLLQELEKSENNFEIEKIKKENQNLQTKVK 397

Query: 384  SPWS---QLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXX 440
                   +L S   N D + +I +N + KL+  I +L K+  + +  + E +        
Sbjct: 398  EMQETIDELESNAWNDDGNDEIKQN-LDKLKQEINNLKKENENLQKQVEENEENAWNDGN 456

Query: 441  XXXGKDTL--IAQLQLEHQQ----HMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIK 494
                ++    + +LQ E++     + E  +   +    ++++E+ K  E+L++ L +E +
Sbjct: 457  NDEIEEIKQNLEKLQKENENLKKINEEKSNDDEINKLKQEISELKKENEELQENLWNENE 516

Query: 495  DVNVKDLIEKLKSAEEQITQ----LNDEIDAANKNMIKVKSNH-KLKLKQMQKTIDNFSK 549
            + + ++ I  LK   E++ Q    L  +I+   +N+     N  K K+ +++  + N  K
Sbjct: 517  NEDNQEEISNLKKENEKLKQNIKELQKQIETNEENLWNENENDLKQKVTELESEVKNSDK 576

Query: 550  VSDSNKEIVRLTEELHHLSQKVAE--LEEEKGNLQLHLVDYDSGRMI-ESDVYKKMIEME 606
            + + N ++ +  EEL      + E   ++++ N +   +  +   +  E++  KK  EM+
Sbjct: 577  LKEENNKLKKENEELKKEIDDLTENVWKDDEDNQETEKLKQEINNLKKENEELKK--EMD 634

Query: 607  NLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQL--QSDQVCSEIKSVH- 663
             L E+        ES   +L Q+L  L+QKY + E    D+ +L  Q D +  E + ++ 
Sbjct: 635  ELQESTWNESYTEESD--ELKQKLKELEQKYKDTEKSNEDLKKLLEQVDNLQKESEKINQ 692

Query: 664  -LEEQIDALSASK--------KELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYI 714
             LE+QI+    +         K+    +E+   +KE+L    ++L+ + ED+  +++N  
Sbjct: 693  DLEKQIEENQENSDVDENEILKQKVTELESEVKEKEKLN---EELKKENEDLKKEVENLQ 749

Query: 715  QENMDLTDKLE-KMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSK 773
            +   + T+  E K   EK +E+L K   EE +K            E +  ++N E++  K
Sbjct: 750  ENAWNETENEEIKEKLEKENEILQK-QVEENNKTLNDLKQKLSESENEKSVKNSEND--K 806

Query: 774  YKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDH 833
             K ++  +E    +  ++  +L++K D L   L++ +K   E  I  ++  N+       
Sbjct: 807  LKQKVTEIESDFKISNEKSSNLQQKLDVLSQNLEKLEK---EMKISSEK--NQ------- 854

Query: 834  DRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESES 893
                     +++ EN +LQ +   L ++N + Q+ ++ + +  + L  + N       ES
Sbjct: 855  ---------KLQKENSDLQNQFTSLQKQNSDNQLKITSLLKEKSELENQLNENSTQNLES 905

Query: 894  TKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDL----EIEFNTQIESAIRDKKVLNEK 949
               + ++RDL+  + +   + + L  + KK  +DL      + + + +  I++ K+  EK
Sbjct: 906  NSSEKEIRDLKEKITKQNEKIKELEEEVKKGYQDLWGADSDDDSKEKDEEIKNLKLEIEK 965

Query: 950  YEKN-IEYVTQLEA----QLQEYKNNIENLNMNV----EELNKMNLELIDKHVQKQQTQS 1000
              KN +E +  +E     ++++ +N I+ + +++    EE+NK+N E+      +  T +
Sbjct: 966  INKNHLEKIGIVEKEKKNEIEKRENKIKKMRIDLQKKDEEINKLNKEISQNKKDEWSTVT 1025

Query: 1001 PDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENM 1060
                E+ I+ + K N  +KQ   EI    ++I   Q        + E K ++ +   +  
Sbjct: 1026 FGDDEE-ISSLKKENERIKQ---EITEKQKEIEEIQQKLSKFTKENEEKSSEISLLKKEN 1081

Query: 1061 EEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEP 1120
            EE++  + K+  + KQ  EE     +E ++   + K   L  E      E  ++    E 
Sbjct: 1082 EEKLSVLEKENEELKQRIEEFNSFKKENEE--NKQKIYNLGEETKKKLNEISVLKKENEE 1139

Query: 1121 MSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLET 1180
            +    N ++                 ++E  ++ SVL++++  L  +L E  + + + E 
Sbjct: 1140 LKQKLNEINEEMKQKIVDFNEKFSNSKKENEEKLSVLKKENDNLKQKLNEFNSFMKESEE 1199

Query: 1181 LNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWK 1240
                L       +++++ LK + E++     +L+    EL   +S ++ +      E  K
Sbjct: 1200 NKQRLNDLGEETKKKLSILKKENEEMKQNISDLMKENKELNERLSKSIKEN-----EENK 1254

Query: 1241 QHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVT-SLQNKL 1299
            + L + E +F K E E    L     + +Q L+ +    +++ N+I  +++    L+  L
Sbjct: 1255 KKLNENELNF-KQEIEENSLLKKENEENKQKLNEINQEMKKKLNEISNLKRENEDLKRSL 1313

Query: 1300 QDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSY 1359
               EE +  + E    +  + + ++ E ++ K                    ++ EN+  
Sbjct: 1314 NGNEEIIEEMNE----INKENDSIKKENKEMKQNLIPKLQKENEKLNNEISQIQIENEKL 1369

Query: 1360 KQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQK 1419
            K+ Q + +  I+ E +QLK+ +            R  +   ++ +    L+ ++ ++ QK
Sbjct: 1370 KK-QIEEMKQISNEISQLKQEN--------EDLKRSLNGNQEINKENDDLKKENEKLNQK 1420

Query: 1420 THEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKE 1479
              E   +L  ++    N+ + L + +K  E+L+          + K +E  N  E  +K+
Sbjct: 1421 MEEMKKSLVDKS----NLNELLKKLQKENEELSISLSQ-----KQKENEKINE-ELTKKQ 1470

Query: 1480 SEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTN-EMQTALENQEIEIVTLN 1537
             EIE+ K   +L   +  S +   ++ EL +   EE  + N E+   LE  + ++ +LN
Sbjct: 1471 IEIEKQK---DLETNLNNSDANKDEMIELLQNENEETKRNNEELSLLLEKYKHDVDSLN 1526



 Score =  172 bits (419), Expect = 6e-41
 Identities = 261/1388 (18%), Positives = 611/1388 (44%), Gaps = 127/1388 (9%)

Query: 235  EKQRLLKDIESKDVRISSLEEANKLL--EAARFEISLEHSKLA-QELEQXXXXXXXXXXX 291
            E  +  K+  + ++ I  L   N  L  E    +  LE      QEL++           
Sbjct: 161  EMTQKTKEFSNLEIIIKELRAENDQLNDELMNDQAELEEKDAEIQELKEQNEGAYKMKYE 220

Query: 292  XXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLAT 351
                  + ++       EI ++     + + E  K+++    +N  I++  +++E     
Sbjct: 221  TATKTIELLQKQISASQEISKENDALKSKLAEKDKQLQNYNDMNSLIKEQREQIEKLSKN 280

Query: 352  MGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLS--------SETLNQDTDKKIN 403
            +   S    +  K  + + + K       +  + W  +         +E L ++ +   N
Sbjct: 281  IDDSSDFAENEKKYQNEIQNLKKQIEELQENDNAWGDIDDTDEIKQENENLKKEIENLKN 340

Query: 404  KN-EIAKLEMVIQSLNKDLV-----DKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQ 457
            +N EI  L++ I+ L KD++     D E ++ E +            K+    Q +++  
Sbjct: 341  QNKEIGNLQLQIEKL-KDIIKEKESDNESLLQELEKSENNFEIEKIKKENQNLQTKVKEM 399

Query: 458  QHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLND 517
            Q      L     N +  +EI +  ++LKQE+N      N+K   E L+   E+  + N 
Sbjct: 400  QETID-ELESNAWNDDGNDEIKQNLDKLKQEIN------NLKKENENLQKQVEE-NEENA 451

Query: 518  EIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEE 577
              D  N  + ++K N    L+++QK  +N  K+++         +E++ L Q+++EL++E
Sbjct: 452  WNDGNNDEIEEIKQN----LEKLQKENENLKKINEEKSN----DDEINKLKQEISELKKE 503

Query: 578  KGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQEL-HILQQK 636
               LQ +L + +     + ++     E E L +   +    +E+ + +L  E  + L+QK
Sbjct: 504  NEELQENLWNENENEDNQEEISNLKKENEKLKQNIKELQKQIETNEENLWNENENDLKQK 563

Query: 637  YDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTI 696
              E+E ++ +  +L+ +    + ++  L+++ID L+    E     +    + E+L   I
Sbjct: 564  VTELESEVKNSDKLKEENNKLKKENEELKKEIDDLT----ENVWKDDEDNQETEKLKQEI 619

Query: 697  KDLENDKEDIMNKLQNYIQE---NMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGI 753
             +L+ + E++  ++   +QE   N   T++ +++  +K+ EL  K    E+S    +   
Sbjct: 620  NNLKKENEELKKEMDE-LQESTWNESYTEESDELK-QKLKELEQKYKDTEKSNEDLK--- 674

Query: 754  DAKIQERDLYIENIESELSKYKSRICR-LEESIAVME-DRRYSLERKADQLGSYLQEKQK 811
              K+ E+   ++N++ E  K    + + +EE+    + D    L++K  +L S ++EK+K
Sbjct: 675  --KLLEQ---VDNLQKESEKINQDLEKQIEENQENSDVDENEILKQKVTELESEVKEKEK 729

Query: 812  AYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSD 871
               E   + ++L   +  L ++         E E   ++L+K+N+IL ++ +    +L+D
Sbjct: 730  LNEELKKENEDLKKEVENLQEN----AWNETENEEIKEKLEKENEILQKQVEENNKTLND 785

Query: 872  MQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIE 931
            ++Q    L E  N   +  SE+ K + ++ ++ES+ K I++E  + + QK      L++ 
Sbjct: 786  LKQK---LSESENEKSVKNSENDKLKQKVTEIESDFK-ISNEKSSNLQQK------LDV- 834

Query: 932  FNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDK 991
             +  +E   ++ K+ +EK +K  +  + L+ Q    +    +  + +  L K   EL + 
Sbjct: 835  LSQNLEKLEKEMKISSEKNQKLQKENSDLQNQFTSLQKQNSDNQLKITSLLKEKSEL-EN 893

Query: 992  HVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLA 1051
             + +  TQ+ +       EI  L   + +++E+I  L +++           SD +SK  
Sbjct: 894  QLNENSTQNLESNSSE-KEIRDLKEKITKQNEKIKELEEEVKKGYQDLWGADSDDDSK-- 950

Query: 1052 QFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEG 1111
            +   +++N++ E+++++K       H E++ I+ +E+ ++I E +E K+  +M I     
Sbjct: 951  EKDEEIKNLKLEIEKINKN------HLEKIGIVEKEKKNEI-EKRENKIK-KMRID---- 998

Query: 1112 MIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQEC 1171
                  ++   ++ N ++                 ++E   E S L++++ ++  E+ E 
Sbjct: 999  ------LQKKDEEINKLNKEISQNKKDEWSTVTFGDDE---EISSLKKENERIKQEITE- 1048

Query: 1172 YTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQR 1231
              K  ++E +  +L+     N+E+     S++  L  EN+  LS + +    +   +++ 
Sbjct: 1049 --KQKEIEEIQQKLSKFTKENEEK----SSEISLLKKENEEKLSVLEKENEELKQRIEE- 1101

Query: 1232 GFEIAELWKQHLAQREADF-QKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTM- 1289
             F   +   +   Q+  +  ++T+ +L  ++S  + + E+L   +    +E   KIV   
Sbjct: 1102 -FNSFKKENEENKQKIYNLGEETKKKLN-EISVLKKENEELKQKLNEINEEMKQKIVDFN 1159

Query: 1290 EQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXX 1349
            E+ ++ + + ++K   L+   +     +N+      E E+ K                  
Sbjct: 1160 EKFSNSKKENEEKLSVLKKENDNLKQKLNEFNSFMKESEENKQRLNDLGEETKKKLSI-- 1217

Query: 1350 XDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQL 1409
              L+ EN+  KQ    +I ++ +EN +L +              ++N+ E     L  + 
Sbjct: 1218 --LKKENEEMKQ----NISDLMKENKELNERLSKSIKENEENKKKLNENE-----LNFKQ 1266

Query: 1410 ELKDSEIYQKTHEYTIT-LTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHE 1468
            E++++ + +K +E     L + N E +    ++   ++  EDL         I+  +M+E
Sbjct: 1267 EIEENSLLKKENEENKQKLNEINQEMKKKLNEISNLKRENEDLKRSLNGNEEIIE-EMNE 1325

Query: 1469 NANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAEL---NKALEEEVAKTNEMQTA 1525
                 ++++KE++  +  LI +L     E+  LN +++++   N+ L++++ +  ++   
Sbjct: 1326 INKENDSIKKENKEMKQNLIPKLQ---KENEKLNNEISQIQIENEKLKKQIEEMKQISNE 1382

Query: 1526 LENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVP 1585
            +   + E   L   +   Q + + +    +++       ++ +   +D +   ELL  + 
Sbjct: 1383 ISQLKQENEDLKRSLNGNQEINKENDDLKKENEKLNQKMEEMKKSLVDKSNLNELLKKLQ 1442

Query: 1586 RAELDLAM 1593
            +   +L++
Sbjct: 1443 KENEELSI 1450



 Score =  149 bits (362), Expect = 5e-34
 Identities = 266/1255 (21%), Positives = 544/1255 (43%), Gaps = 125/1255 (9%)

Query: 305  EEKTEIEEKGSLEIANMTELTKKIE-LLEHLNCQIRQTNKELENKLATMGTESKAVSSPS 363
            +EK    +K  + +   T   + +E +L  +N      + ++E +L     +SKA+ S  
Sbjct: 3    DEKNMDPQKMKVLLKQKTARIRDLEKMLSQMNAPSVDNSSKIE-ELEQQLEDSKALISAL 61

Query: 364  KKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVD 423
            ++    +S+K   N      S  SQ ++   N D    + K +IA+ +  I+SLN +L +
Sbjct: 62   QES---VSQK---NAEISRLSLISQSNARNQNSDLIASLQK-KIAEQQQEIESLNNELWN 114

Query: 424  KEYVISEKD---TXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAK 480
             +   SEKD                   ++      +       L  +   T++ + +  
Sbjct: 115  DDPNESEKDIEIQNLKSQIQKLTKNQPQVSPASNNAELDTLRSQLAEMTQKTKEFSNLEI 174

Query: 481  VQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQM 540
            + ++L+ E ND++ D  + D  E L+  + +I +L ++ + A          +K+K +  
Sbjct: 175  IIKELRAE-NDQLNDELMNDQAE-LEEKDAEIQELKEQNEGA----------YKMKYETA 222

Query: 541  QKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNL-QLHLVDYDSGRMIESDVY 599
             KTI+   K   +++EI   ++E   L  K+AE +++  N   ++ +  +    IE  + 
Sbjct: 223  TKTIELLQKQISASQEI---SKENDALKSKLAEKDKQLQNYNDMNSLIKEQREQIEK-LS 278

Query: 600  KKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEI 659
            K + +  + AE   K  + +++ K   ++EL      + +++D         +D++  E 
Sbjct: 279  KNIDDSSDFAENEKKYQNEIQNLK-KQIEELQENDNAWGDIDD---------TDEIKQE- 327

Query: 660  KSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMD 719
             + +L+++I+ L    KE    I NL+L  E+L   IK+ E+D E ++ +L+    EN  
Sbjct: 328  -NENLKKEIENLKNQNKE----IGNLQLQIEKLKDIIKEKESDNESLLQELEK--SENNF 380

Query: 720  LTDKLEKMSAE---KISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKS 776
              +K++K +     K+ E+   I+ E +S      G D +I++    ++ ++ E++  K 
Sbjct: 381  EIEKIKKENQNLQTKVKEMQETID-ELESNAWNDDGND-EIKQN---LDKLKQEINNLKK 435

Query: 777  RICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRV 836
                L++ +   E+  ++ +   D++    Q  +K   E   +  + +N      D    
Sbjct: 436  ENENLQKQVEENEENAWN-DGNNDEIEEIKQNLEKLQKEN--ENLKKINEEKSNDDEINK 492

Query: 837  VEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKY 896
            +++++ E++ EN+ELQ+    L  EN+N      D Q+  + L +K N     E      
Sbjct: 493  LKQEISELKKENEELQEN---LWNENEN-----EDNQEEISNL-KKEN-----EKLKQNI 538

Query: 897  QTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEY 956
            +   + +E+N + + +E++  + QK  E+E  E++ + +++      K  NE+ +K I+ 
Sbjct: 539  KELQKQIETNEENLWNENENDLKQKVTELES-EVKNSDKLKEENNKLKKENEELKKEIDD 597

Query: 957  VTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNA 1016
            +T+   +  E     E L   +  L K N EL     +  + Q   + E Y  E ++L  
Sbjct: 598  LTENVWKDDEDNQETEKLKQEINNLKKENEEL---KKEMDELQESTWNESYTEESDELKQ 654

Query: 1017 LLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQ 1076
             LK+ +++     +K N      +  V + + +  +    LE   EE Q  S        
Sbjct: 655  KLKELEQK-YKDTEKSNEDLKKLLEQVDNLQKESEKINQDLEKQIEENQENS-----DVD 708

Query: 1077 HNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXX 1136
             NE L+  V E + ++KE KE KL  E+   K E   +   +E + ++A N         
Sbjct: 709  ENEILKQKVTELESEVKE-KE-KLNEEL---KKENEDLKKEVENLQENAWN--------- 754

Query: 1137 XXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQI 1196
                  +++E+ E  +E  +LQ+Q  + N  L +   K+ + E   +     +   ++++
Sbjct: 755  -ETENEEIKEKLE--KENEILQKQVEENNKTLNDLKQKLSESENEKSVKNSENDKLKQKV 811

Query: 1197 NQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHE 1256
             +++S  +  N ++ NL   +  L  ++     ++  +I+    Q L +  +D Q     
Sbjct: 812  TEIESDFKISNEKSSNLQQKLDVLSQNLEKL--EKEMKISSEKNQKLQKENSDLQNQFTS 869

Query: 1257 LRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADV 1316
            L+ Q S  + K   LL   +S  + + N+  T     +L++   +KE  +R+L+EK    
Sbjct: 870  LQKQNSDNQLKITSLLKE-KSELENQLNENSTQ----NLESNSSEKE--IRDLKEKITKQ 922

Query: 1317 INQIEILRSEI-EDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENA 1375
              +I+ L  E+ +  +  +                +L+ E +   +   + I  I E+  
Sbjct: 923  NEKIKELEEEVKKGYQDLWGADSDDDSKEKDEEIKNLKLEIEKINKNHLEKI-GIVEKEK 981

Query: 1376 QLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFE 1435
            + +               +  D E   L        KD E    T      ++    E E
Sbjct: 982  KNEIEKRENKIKKMRIDLQKKDEEINKLNKEISQNKKD-EWSTVTFGDDEEISSLKKENE 1040

Query: 1436 NVRQQLVEYEKRIEDL-------TYEKESELAILRLKMHENANHYETMQKESEIERVKLI 1488
             ++Q++ E +K IE++       T E E + + + L   EN      ++KE+E E  + I
Sbjct: 1041 RIKQEITEKQKEIEEIQQKLSKFTKENEEKSSEISLLKKENEEKLSVLEKENE-ELKQRI 1099

Query: 1489 EELNVKITESVSLNKQVAELNKALEEEVAKTNEMQT-ALENQEI--EIVTLNDEI 1540
            EE N    E+    +++  L    EE   K NE+     EN+E+  ++  +N+E+
Sbjct: 1100 EEFNSFKKENEENKQKIYNLG---EETKKKLNEISVLKKENEELKQKLNEINEEM 1151



 Score =  142 bits (345), Expect = 5e-32
 Identities = 260/1181 (22%), Positives = 504/1181 (42%), Gaps = 107/1181 (9%)

Query: 471  NTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVK 530
            N   V+  +K++E L+Q+L D    ++        K+AE     L  + +A N+N   + 
Sbjct: 34   NAPSVDNSSKIEE-LEQQLEDSKALISALQESVSQKNAEISRLSLISQSNARNQNSDLIA 92

Query: 531  SNHKLKLKQMQKTIDNFS--------KVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQ 582
            S  K K+ + Q+ I++ +          S+ + EI  L  ++  L++   ++     N +
Sbjct: 93   SLQK-KIAEQQQEIESLNNELWNDDPNESEKDIEIQNLKSQIQKLTKNQPQVSPASNNAE 151

Query: 583  LHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFD-LVQELHILQQKYDEVE 641
            L     D+ R   +++ +K  E  NL E  +K +     Q  D L+ +   L++K  E++
Sbjct: 152  L-----DTLRSQLAEMTQKTKEFSNL-EIIIKELRAENDQLNDELMNDQAELEEKDAEIQ 205

Query: 642  DKLADISQLQSDQVCSEIKSVH-LEEQIDA-LSASKKELALVIENLKLDKE-QLYGTIKD 698
            +           +  +  K++  L++QI A    SK+  AL  +  + DK+ Q Y  +  
Sbjct: 206  ELKEQNEGAYKMKYETATKTIELLQKQISASQEISKENDALKSKLAEKDKQLQNYNDMNS 265

Query: 699  LENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQ 758
            L  ++ + + KL   I ++ D  +  EK    +I  L  +I  EE  +    +G      
Sbjct: 266  LIKEQREQIEKLSKNIDDSSDFAEN-EKKYQNEIQNLKKQI--EELQENDNAWGDIDDTD 322

Query: 759  ERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTI 818
            E     EN++ E+   K++   +      +E  +  ++ K     S LQE +K+ + + I
Sbjct: 323  EIKQENENLKKEIENLKNQNKEIGNLQLQIEKLKDIIKEKESDNESLLQELEKSENNFEI 382

Query: 819  QEDELVNRLAVLMDHDRVVEKQLLEIEHE------NKELQKKNQILLEENQNLQISLSDM 872
            ++ +  N+   L    + +++ + E+E        N E+++    L +E  NL+    ++
Sbjct: 383  EKIKKENQ--NLQTKVKEMQETIDELESNAWNDDGNDEIKQNLDKLKQEINNLKKENENL 440

Query: 873  QQHYNALVEKA-NRTDLAESESTKYQTQ-LRDLESNLKRITHEH---------QTLIVQK 921
            Q+      E A N  +  E E  K   + L+    NLK+I  E          +  I + 
Sbjct: 441  QKQVEENEENAWNDGNNDEIEEIKQNLEKLQKENENLKKINEEKSNDDEINKLKQEISEL 500

Query: 922  KKEIEDLEIEF-----NTQIESAIRDKKVLNEKYEKNI-EYVTQLEAQLQEYKNNIEN-L 974
            KKE E+L+        N   +  I + K  NEK ++NI E   Q+E   +   N  EN L
Sbjct: 501  KKENEELQENLWNENENEDNQEEISNLKKENEKLKQNIKELQKQIETNEENLWNENENDL 560

Query: 975  NMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDE---EIIALNQK 1031
               V EL +  ++  DK ++++  +     E+   EI+ L   + + DE   E   L Q+
Sbjct: 561  KQKVTEL-ESEVKNSDK-LKEENNKLKKENEELKKEIDDLTENVWKDDEDNQETEKLKQE 618

Query: 1032 INNAQVSYMSMVSDYESKL-----AQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVR 1086
            INN +     +  + +          +T + + ++++++ + ++  D+++ NE+L+ L+ 
Sbjct: 619  INNLKKENEELKKEMDELQESTWNESYTEESDELKQKLKELEQKYKDTEKSNEDLKKLLE 678

Query: 1087 EQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQE 1146
            + D+  KE ++     E  I + +        E +      ++            LK +E
Sbjct: 679  QVDNLQKESEKINQDLEKQIEENQENSDVDENEILKQKVTELESEVKEKEKLNEELK-KE 737

Query: 1147 EEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQ- 1205
             E+  +E   LQE +A   TE +E   K   LE  N  L      N + +N LK KL + 
Sbjct: 738  NEDLKKEVENLQE-NAWNETENEEIKEK---LEKENEILQKQVEENNKTLNDLKQKLSES 793

Query: 1206 ------LNTENDNLLSTVAELRS--SISSAVDQRGFEIAELWKQHLAQREADFQKTEHEL 1257
                   N+END L   V E+ S   IS+       +  ++  Q+L + E +  K   E 
Sbjct: 794  ENEKSVKNSENDKLKQKVTEIESDFKISNEKSSNLQQKLDVLSQNLEKLEKE-MKISSEK 852

Query: 1258 RVQLSAFESKYEQLLDSVQSSTQEETNKIVT-MEQVTSLQNKLQDKEEHLRNLQEKYADV 1316
              +L    S  +    S+Q    +   KI + +++ + L+N+L   E   +NL+   ++ 
Sbjct: 853  NQKLQKENSDLQNQFTSLQKQNSDNQLKITSLLKEKSELENQL--NENSTQNLESNSSE- 909

Query: 1317 INQIEILRSEI--EDEKVAFXXXXXXXXXXXXXXXXDL-RTENQSYKQMQEQSILNINEE 1373
              +I  L+ +I  ++EK+                  DL   ++    + +++ I N+  E
Sbjct: 910  -KEIRDLKEKITKQNEKI------KELEEEVKKGYQDLWGADSDDDSKEKDEEIKNLKLE 962

Query: 1374 NAQLKKSS-XXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRND 1432
              ++ K+               +   E K+ ++   L+ KD EI +   E +     + D
Sbjct: 963  IEKINKNHLEKIGIVEKEKKNEIEKRENKIKKMRIDLQKKDEEINKLNKEIS---QNKKD 1019

Query: 1433 EFENVR-------QQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERV 1485
            E+  V          L +  +RI+    EK+ E+  ++ K+ +     E    E  + + 
Sbjct: 1020 EWSTVTFGDDEEISSLKKENERIKQEITEKQKEIEEIQQKLSKFTKENEEKSSEISLLKK 1079

Query: 1486 KLIEELNVKITESVSLNKQVAELN---KALEEEVAKTNEMQTALENQEIEIVTLNDEITN 1542
            +  E+L+V   E+  L +++ E N   K  EE   K   +    + +  EI  L  E   
Sbjct: 1080 ENEEKLSVLEKENEELKQRIEEFNSFKKENEENKQKIYNLGEETKKKLNEISVLKKENEE 1139

Query: 1543 LQNMVRASSSKI-QKHVSF---ASDTKQGRDEQLDNTMNKE 1579
            L+  +   + ++ QK V F    S++K+  +E+L + + KE
Sbjct: 1140 LKQKLNEINEEMKQKIVDFNEKFSNSKKENEEKL-SVLKKE 1179



 Score =  136 bits (330), Expect = 4e-30
 Identities = 212/975 (21%), Positives = 429/975 (44%), Gaps = 104/975 (10%)

Query: 144  VTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXX 203
            VT L + +KEK+     L+ + + ++  + +LQE    + +  E K K            
Sbjct: 717  VTELESEVKEKEKLNEELKKENEDLKKEVENLQENAWNETENEEIKEK-LEKENEILQKQ 775

Query: 204  XXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAA 263
                     D KQ++++  EN  +++    D+ ++ + +IES D +IS+ + +N      
Sbjct: 776  VEENNKTLNDLKQKLSE-SENEKSVKNSENDKLKQKVTEIES-DFKISNEKSSN------ 827

Query: 264  RFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTE 323
               +  +   L+Q LE+              L K++ +    + T ++++ S     +T 
Sbjct: 828  ---LQQKLDVLSQNLEKLEKEMKISSEKNQKLQKENSDLQ-NQFTSLQKQNSDNQLKITS 883

Query: 324  LTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMK 383
            L K+                ELEN+L    T++   +S  K+   L  + + +N   K  
Sbjct: 884  LLKE--------------KSELENQLNENSTQNLESNSSEKEIRDLKEKITKQNEKIKEL 929

Query: 384  SPWSQLSSETL---NQDTDKKINKNEIAKLEMVIQSLNKD------LVDKE--YVISEKD 432
                +   + L   + D D K    EI  L++ I+ +NK+      +V+KE    I +++
Sbjct: 930  EEEVKKGYQDLWGADSDDDSKEKDEEIKNLKLEIEKINKNHLEKIGIVEKEKKNEIEKRE 989

Query: 433  TXXXXXXXXXXGKDTLIAQLQLEHQQHMEGP-SLIHVGTNTEDVNEIAKVQEQLKQELND 491
                        KD  I +L  E  Q+ +   S +  G + E+++ + K  E++KQE+ +
Sbjct: 990  NKIKKMRIDLQKKDEEINKLNKEISQNKKDEWSTVTFG-DDEEISSLKKENERIKQEITE 1048

Query: 492  EIKDV-NVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKV 550
            + K++  ++  + K     E+ +     +   N+  + V      +LKQ  +  ++F K 
Sbjct: 1049 KQKEIEEIQQKLSKFTKENEEKSSEISLLKKENEEKLSVLEKENEELKQRIEEFNSFKKE 1108

Query: 551  SDSNKE-IVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLA 609
            ++ NK+ I  L EE      +++ L++E   L+  L +      I  ++ +K+++     
Sbjct: 1109 NEENKQKIYNLGEETKKKLNEISVLKKENEELKQKLNE------INEEMKQKIVDFN--- 1159

Query: 610  ETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQID 669
                       + K +  ++L +L+++ D ++ KL + +    +   SE     L    D
Sbjct: 1160 -------EKFSNSKKENEEKLSVLKKENDNLKQKLNEFNSFMKE---SEENKQRLN---D 1206

Query: 670  ALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKL---EK 726
                +KK+L++    LK + E++   I DL  + +++  +L   I+EN +   KL   E 
Sbjct: 1207 LGEETKKKLSI----LKKENEEMKQNISDLMKENKELNERLSKSIKENEENKKKLNENEL 1262

Query: 727  MSAEKISE--LLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEES 784
               ++I E  LL K N E + K+     I+ +++++   I N++ E    K  +   EE 
Sbjct: 1263 NFKQEIEENSLLKKENEENKQKLNE---INQEMKKKLNEISNLKRENEDLKRSLNGNEEI 1319

Query: 785  IAVMEDRRYSLERKADQLGSYLQE-KQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLE 843
            I  M +    + ++ D +    +E KQ    +   + ++L N ++ +   +  ++KQ+ E
Sbjct: 1320 IEEMNE----INKENDSIKKENKEMKQNLIPKLQKENEKLNNEISQIQIENEKLKKQIEE 1375

Query: 844  IEHENKELQKKNQILLEENQNLQISLSDMQQ--HYNALVEKAN-RTDLAESESTKYQTQL 900
            ++  + E+ +    L +EN++L+ SL+  Q+    N  ++K N + +    E  K     
Sbjct: 1376 MKQISNEISQ----LKQENEDLKRSLNGNQEINKENDDLKKENEKLNQKMEEMKKSLVDK 1431

Query: 901  RDLESNLKRITHEHQTLIV---QKKKEIEDLEIEF-NTQIE-SAIRDKKV-LNEKYEKNI 954
             +L   LK++  E++ L +   QK+KE E +  E    QIE    +D +  LN       
Sbjct: 1432 SNLNELLKKLQKENEELSISLSQKQKENEKINEELTKKQIEIEKQKDLETNLNNSDANKD 1491

Query: 955  EYVTQLEAQLQEYKNNIENLNM-------NVEELNKMNLELIDKHVQKQQTQSPDYTEQY 1007
            E +  L+ + +E K N E L++       +V+ LN  NL LI ++ QK+ T +   TE+ 
Sbjct: 1492 EMIELLQNENEETKRNNEELSLLLEKYKHDVDSLNAKNLHLIKENEQKEITINNLNTEK- 1550

Query: 1008 INEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRV 1067
              E+ K+N  L+Q  + I+   ++    +V  +       +   +   K+ +    MQ +
Sbjct: 1551 -KELGKINKQLEQ-SKSILESQKEYEEMKVKQVEKPKQINANDIKEKEKMNDCMMRMQYL 1608

Query: 1068 SKQLLDSKQHNEELQ 1082
               L+     N   Q
Sbjct: 1609 QSALIQFFHQNTSTQ 1623



 Score =  120 bits (288), Expect = 4e-25
 Identities = 211/1029 (20%), Positives = 460/1029 (44%), Gaps = 110/1029 (10%)

Query: 632  ILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSA--SKKELALVIENLKLDK 689
            +L+QK   + D    +SQ+ +  V +  K   LE+Q++   A  S  + ++  +N ++ +
Sbjct: 15   LLKQKTARIRDLEKMLSQMNAPSVDNSSKIEELEQQLEDSKALISALQESVSQKNAEISR 74

Query: 690  EQLYGTIKDLENDKEDIMNKLQNYI----QENMDLTDKLEKMSAEKISELLAKINHEEQS 745
              L     +  N   D++  LQ  I    QE   L ++L      +  + +   N + Q 
Sbjct: 75   LSLISQ-SNARNQNSDLIASLQKKIAEQQQEIESLNNELWNDDPNESEKDIEIQNLKSQI 133

Query: 746  KIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSY 805
            +  T+          +  ++ + S+L++   +         ++++ R   ++  D+L + 
Sbjct: 134  QKLTKNQPQVSPASNNAELDTLRSQLAEMTQKTKEFSNLEIIIKELRAENDQLNDELMND 193

Query: 806  LQEKQKAYSEYTIQEDELVNRLAVLMDHD------RVVEKQLLEIEHENKELQKKNQILL 859
              E ++  +E  IQE +  N  A  M ++       +++KQ+   +  +KE       L 
Sbjct: 194  QAELEEKDAE--IQELKEQNEGAYKMKYETATKTIELLQKQISASQEISKENDALKSKLA 251

Query: 860  EENQNLQ--ISLSDMQQHYNALVEKANR-----TDLAESESTKYQTQLRDLESNLKRI-- 910
            E+++ LQ    ++ + +     +EK ++     +D AE+E  KYQ ++++L+  ++ +  
Sbjct: 252  EKDKQLQNYNDMNSLIKEQREQIEKLSKNIDDSSDFAENEK-KYQNEIQNLKKQIEELQE 310

Query: 911  ----------THEHQTLIVQKKKEIEDLEIE----FNTQIESAIRDKKVLNEKYEKNIEY 956
                      T E +      KKEIE+L+ +     N Q++   + K ++ EK   N   
Sbjct: 311  NDNAWGDIDDTDEIKQENENLKKEIENLKNQNKEIGNLQLQIE-KLKDIIKEKESDNESL 369

Query: 957  VTQLEA-----QLQEYKNNIENLNMNVEELNKMNLEL----IDKHVQKQQTQSPDYTEQY 1007
            + +LE      ++++ K   +NL   V+E+ +   EL     +     +  Q+ D  +Q 
Sbjct: 370  LQELEKSENNFEIEKIKKENQNLQTKVKEMQETIDELESNAWNDDGNDEIKQNLDKLKQE 429

Query: 1008 INEINKLNA-LLKQKDE-EIIALNQKINNAQVSYMSMVSDYESKLAQFTTKL---ENMEE 1062
            IN + K N  L KQ +E E  A N   NN ++  +    +   K  +   K+   ++ ++
Sbjct: 430  INNLKKENENLQKQVEENEENAWNDG-NNDEIEEIKQNLEKLQKENENLKKINEEKSNDD 488

Query: 1063 EMQRVSKQLLDSKQHNEELQILV------REQDDQIKELKETKLTFEMNIPKTEGMIISS 1116
            E+ ++ +++ + K+ NEELQ  +       +  ++I  LK+     + NI + +  I ++
Sbjct: 489  EINKLKQEISELKKENEELQENLWNENENEDNQEEISNLKKENEKLKQNIKELQKQIETN 548

Query: 1117 TIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKII 1176
                 +++ N++              KV E E  ++    L+E++ KL  E +E   +I 
Sbjct: 549  EENLWNENENDLKQ------------KVTELESEVKNSDKLKEENNKLKKENEELKKEID 596

Query: 1177 QLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSI-SSAVDQRGFEI 1235
             L    TE    D  + ++  +LK ++  L  EN+ L   + EL+ S  + +  +   E+
Sbjct: 597  DL----TENVWKDDEDNQETEKLKQEINNLKKENEELKKEMDELQESTWNESYTEESDEL 652

Query: 1236 AELWKQHLAQREADFQKTEHELRVQLSAFES------KYEQLLDSVQSSTQEETN---KI 1286
             +  K+ L Q+  D +K+  +L+  L   ++      K  Q L+      QE ++     
Sbjct: 653  KQKLKE-LEQKYKDTEKSNEDLKKLLEQVDNLQKESEKINQDLEKQIEENQENSDVDENE 711

Query: 1287 VTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILR----SEIEDEKVAFXXXXXXXX 1342
            +  ++VT L++++++KE+    L+++  D+  ++E L+    +E E+E++          
Sbjct: 712  ILKQKVTELESEVKEKEKLNEELKKENEDLKKEVENLQENAWNETENEEIKEKLEKENEI 771

Query: 1343 XXXXXXXXDLRTENQSYKQMQEQSILNI-NEENAQLKKSSXXXXXXXXXXXXRVNDAEAK 1401
                    +    +   K  + ++  ++ N EN +LK+              + ++ + K
Sbjct: 772  LQKQVEENNKTLNDLKQKLSESENEKSVKNSENDKLKQKVTEIESDFKISNEKSSNLQQK 831

Query: 1402 VLELTHQLELKDSEI---YQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESE 1458
            +  L+  LE  + E+    +K  +     +   ++F ++++Q  + + +I  L  EK   
Sbjct: 832  LDVLSQNLEKLEKEMKISSEKNQKLQKENSDLQNQFTSLQKQNSDNQLKITSLLKEKSE- 890

Query: 1459 LAILRLKMHENA-NHYETMQKESEIERVK-LIEELNVKITE-SVSLNKQVAELNKALEEE 1515
               L  +++EN+  + E+   E EI  +K  I + N KI E    + K   +L  A  ++
Sbjct: 891  ---LENQLNENSTQNLESNSSEKEIRDLKEKITKQNEKIKELEEEVKKGYQDLWGADSDD 947

Query: 1516 VAKTNEMQTALENQEIEIVTLN-DEITNLQNMVRASSSKIQKHVSFASDTK---QGRDEQ 1571
             +K  E    ++N ++EI  +N + +  +  + +   ++I+K  +     +   Q +DE+
Sbjct: 948  DSK--EKDEEIKNLKLEIEKINKNHLEKIGIVEKEKKNEIEKRENKIKKMRIDLQKKDEE 1005

Query: 1572 LDNTMNKEL 1580
            + N +NKE+
Sbjct: 1006 I-NKLNKEI 1013


>UniRef50_A7TQ63 Cluster: Putative uncharacterized protein; n=1;
            Vanderwaltozyma polyspora DSM 70294|Rep: Putative
            uncharacterized protein - Vanderwaltozyma polyspora DSM
            70294
          Length = 2546

 Score =  197 bits (481), Expect = 2e-48
 Identities = 296/1474 (20%), Positives = 637/1474 (43%), Gaps = 139/1474 (9%)

Query: 164  KMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXX---XXXXXXXXXXEDTKQQMTK 220
            +++  E  I DLQ  +  K+  ++  NK  +                        +++  
Sbjct: 878  ELESTEKQITDLQSNLESKNTELDNLNKEKSGLMKELTEWKAKFKSHDALVPKLTEKLKS 937

Query: 221  MQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQ 280
            +  ++  ++ E  +   +L++  ++K   +SSL E+   L+  + +I  E SKL  ++ +
Sbjct: 938  LANSYKELQTERDNYSSQLIEINKNKTSELSSLSESISNLKIEKDKILDEKSKLINKVSE 997

Query: 281  XXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKI-ELLEHLNCQIR 339
                            +  I  +C+   E +EK  L    + EL   + E L+ L  Q  
Sbjct: 998  ---------------LESQITENCKIFEEEKEKLILSKDELEELVIDLNEQLKELETQKE 1042

Query: 340  QTNK---ELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQ 396
             T+K   EL   +A + T+ K   S   +   L+  +  +N  +  +S  S L ++    
Sbjct: 1043 TTSKNADELNKSIANLNTQLKQKDSKLIELEELV--EVTKNNLNDSESQVSNLIAKISEL 1100

Query: 397  DTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEH 456
            D + K  K E+ KLE  I  +       +       T               I  L+ E+
Sbjct: 1101 DEENKSVKLEVEKLENEITEIKNSHKSAQKETDTLQTKLDETELLLQSSKEEILSLKNEY 1160

Query: 457  QQHMEGPSLIHVG--TNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQ 514
               +     +      ++E + E+ K    L QE  + I   N K L E+    EE+   
Sbjct: 1161 SSTLSDKENLENSEKKSSEKIEELEKNFSNL-QEQFENITAEN-KSLKEECSGTEEKFKD 1218

Query: 515  LNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSK-VSDSNKEIVRLTEELHHLSQKVAE 573
            +N+++D   +  I   S+ K KL  +   ID+  K +S+ N+++  ++E++  + +    
Sbjct: 1219 VNEKLDQYGET-ISSLSDEKDKLNGI---IDDKEKIISNLNEKLESISEDIDIIEKAKNL 1274

Query: 574  LEEEKGNLQLHLVDYDSGRMIESDVYKKM-IEMENLAETRL-KAISL--LESQKFDLVQE 629
            LEE+   +   L D ++G      +Y  + IE E L +T   K+ +L  LE++   L + 
Sbjct: 1275 LEEKLATMTSELNDSENGSSELRSLYDSLKIEFEELQKTNSDKSANLKELENKHTSLTET 1334

Query: 630  LHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDK 689
              IL +   ++E  + D  +++ D    E +   L  + + L   K +L +++E      
Sbjct: 1335 QEILLEDKKKMESSINDYVKIKDD---LEKEKEDLLNKYNVLEDKKDKLEIILEENNSSI 1391

Query: 690  EQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQT 749
            + L  +I  L+ + E   N++ + ++  M+ ++   K  A +  + ++++  EE +K++ 
Sbjct: 1392 KVLEHSIDALKKENEIYKNEIHD-MKLQMESSNSEYKNKAGEQEKKISRLK-EECNKLKN 1449

Query: 750  QFGIDAKIQERDLYIENI----ESELSKYKSRICRLEESIAVMEDRRYSLER-KADQLGS 804
             +  + KI++ ++  +N+    ++E  +++ +I  L++ I  +E  +   E+   +Q  +
Sbjct: 1450 SY--EEKIEKLEVESKNLSLGHDTEKKQFEDKITSLKQEIISIEKSKKQDEKVLKNQKNT 1507

Query: 805  YLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQN 864
              +E ++   ++T  E+E + +L    +    V K+ L+IE           +L  + + 
Sbjct: 1508 LQKELEELKDQFTNSENEYIKKLDNFQNEINSVRKEKLDIE----------AVLNSKIET 1557

Query: 865  LQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKE 924
            L+  LS  ++  + ++EK+N+  L + E    Q  L      L  + +E  TL +    E
Sbjct: 1558 LKADLSKSEEK-SLILEKSNKEHLIKME--VIQKSLEKQNKELDILGNEKDTLTMNLNNE 1614

Query: 925  IEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKM 984
            I+ L+ E N++++                   +  L+ +L     N+E++ +  ++L + 
Sbjct: 1615 IKGLKEEINSKVDQ------------------IGNLKTELNTVSENMEDIQVRYDQLKEE 1656

Query: 985  NLELIDKHVQKQQTQSPDYTEQYINEIN----KLNALLKQKDEEIIALNQKINNAQVSYM 1040
              E+ DK ++ ++    +++   I+++N     L A +  KDEE   L ++    ++S  
Sbjct: 1657 KSEISDKLIESEEKLKENFSS--ISDLNSSVISLEASIISKDEEYTLLKKEFEEVKISKQ 1714

Query: 1041 SMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSK--QHNEELQILVREQDDQIKELKET 1098
             + +  +  L +++      E +++ +  + LDSK  + ++E ++L    D+  +E  E 
Sbjct: 1715 ELDNQKDKLLEEYSIMKRTNESKLKDLRNE-LDSKIIKFDKERKLLNEGSDNIAQEYSEK 1773

Query: 1099 KLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQ 1158
              + E  +   +  I S   + +S+   N+             L+ +  EE  +  S L 
Sbjct: 1774 VTSLEEELRNQK--IYSD--DKISELEENIKSKNNALTEKSNLLQ-KRLEEIKELESTLS 1828

Query: 1159 EQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVA 1218
            +  A L   ++    K  + E +  EL+  +       N++K K+E++ +  ++L++ + 
Sbjct: 1829 KYKADLEATMKNSDLKNDEFENVCKELSVKE-------NEIK-KIEEILSSKEDLIAEIE 1880

Query: 1219 ELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSS 1278
              + ++   ++++           L ++E+  +  + ++ VQ    + K  +  D++Q  
Sbjct: 1881 SQKDNLKDELNEKSL--------LLDKKESQLEAFQEDVEVQKENLQKKITE-YDNLQKL 1931

Query: 1279 TQEETNKIVTME-QVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXX 1337
               +  K+V  E Q+  L+ KL+    HL+  + KY       E L  E  + K      
Sbjct: 1932 MSLDNKKLVKCEKQIEDLELKLESSSNHLKEQEGKY-------EKLEFESGENK----KL 1980

Query: 1338 XXXXXXXXXXXXXDLRTENQSYKQMQEQ-SILNINEENAQLKKSSXXXXXXXXXXXXRVN 1396
                         D+       +++ ++ S L  N EN +L                +  
Sbjct: 1981 ISEKDELIQTLQLDISNNKDEIQKLSDKISTLQNNSENTELTLEEKEKMVDELNSKLQEK 2040

Query: 1397 DAEAKVLEL-THQL-ELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYE 1454
            +A+ + LEL  ++L E  D E+ + + E  I      DE    +Q++ E + +I+D   E
Sbjct: 2041 EAQVETLELDLNKLKETLDKEL-ESSSELQIAHDNLRDENIIQKQKITELKVKIDD--SE 2097

Query: 1455 KESELAILRLK-MHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALE 1513
            K+S++ I  +K M EN            I+  K+ E+L+ K +E   LNK++AE  K  E
Sbjct: 2098 KDSQVIIDNMKEMEENIMDLRNDLSSKTIQIEKVNEDLSSKNSEIEQLNKKLAE--KCAE 2155

Query: 1514 EEVAKTNEMQTA--LENQEIEIVTLNDEITNLQNMVRASSSKIQKHVS---FASDTKQGR 1568
             +  K+  + ++   E+++ ++  L+DEI  L+  +   +  ++K  S    A++T    
Sbjct: 2156 YDSIKSELVASSKLSESEKNDMKQLSDEINELKEQLELKNENLKKVTSDLQIANNTSDKY 2215

Query: 1569 DEQLD--NTMNKELLDAVPRAELDLAMYMLHQRD 1600
            +++L   N   +E+   +P  +  L +  +   D
Sbjct: 2216 NDELKVANNTIREIESKIPNLQKQLDLKEIEYND 2249



 Score =  173 bits (422), Expect = 3e-41
 Identities = 281/1434 (19%), Positives = 610/1434 (42%), Gaps = 120/1434 (8%)

Query: 224  NFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLL--EAARFEISLEHSKLAQELEQX 281
            N IA  +E  +E + +  ++E  +  I+ ++ ++K    E    +  L+ ++L  +  + 
Sbjct: 1092 NLIAKISELDEENKSVKLEVEKLENEITEIKNSHKSAQKETDTLQTKLDETELLLQSSKE 1151

Query: 282  XXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTE----LTKKIELLEHLNCQ 337
                           K+++E S ++ +E  E+     +N+ E    +T + + L+     
Sbjct: 1152 EILSLKNEYSSTLSDKENLENSEKKSSEKIEELEKNFSNLQEQFENITAENKSLKEECSG 1211

Query: 338  IRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQD 397
              +  K++  KL   G    ++S    K + +I  K      S +      +S +    +
Sbjct: 1212 TEEKFKDVNEKLDQYGETISSLSDEKDKLNGIIDDKE--KIISNLNEKLESISEDIDIIE 1269

Query: 398  TDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQ 457
              K + + ++A +   +        +   +                 K   + +L+ +H 
Sbjct: 1270 KAKNLLEEKLATMTSELNDSENGSSELRSLYDSLKIEFEELQKTNSDKSANLKELENKHT 1329

Query: 458  QHMEGPSLIHVGTNTED--VNEIAKVQEQLKQELNDEIKDVNV----KDLIEK-LKSAEE 510
               E   ++       +  +N+  K+++ L++E  D +   NV    KD +E  L+    
Sbjct: 1330 SLTETQEILLEDKKKMESSINDYVKIKDDLEKEKEDLLNKYNVLEDKKDKLEIILEENNS 1389

Query: 511  QITQLNDEIDAANK-NMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLS- 568
             I  L   IDA  K N I     H +KL+      +  +K  +  K+I RL EE + L  
Sbjct: 1390 SIKVLEHSIDALKKENEIYKNEIHDMKLQMESSNSEYKNKAGEQEKKISRLKEECNKLKN 1449

Query: 569  ---QKVAELEEEKGNLQLHLVDYDSGR-MIESDVYKKMIEMENLAETRLKAISLLESQKF 624
               +K+ +LE E  NL L    +D+ +   E  +     E+ ++ +++ +   +L++QK 
Sbjct: 1450 SYEEKIEKLEVESKNLSL---GHDTEKKQFEDKITSLKQEIISIEKSKKQDEKVLKNQKN 1506

Query: 625  DLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEE-QIDALSASKKELALVIE 683
             L +EL  L+ ++   E++   I +L + Q  +EI SV  E+  I+A+  SK      IE
Sbjct: 1507 TLQKELEELKDQFTNSENEY--IKKLDNFQ--NEINSVRKEKLDIEAVLNSK------IE 1556

Query: 684  NLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDK-LEKMSAEKISELLAKINHE 742
             LK D  +       LE   ++ + K++  IQ++++  +K L+ +  EK   L   +N+E
Sbjct: 1557 TLKADLSKSEEKSLILEKSNKEHLIKME-VIQKSLEKQNKELDILGNEK-DTLTMNLNNE 1614

Query: 743  EQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQL 802
             +       G+  +I  +   I N+++EL+     +  ++     +++ +  +  K  + 
Sbjct: 1615 IK-------GLKEEINSKVDQIGNLKTELNTVSENMEDIQVRYDQLKEEKSEISDKLIES 1667

Query: 803  GSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEEN 862
               L+E   + S+       L   +    +   +++K+  E++   +EL  +   LLEE 
Sbjct: 1668 EEKLKENFSSISDLNSSVISLEASIISKDEEYTLLKKEFEEVKISKQELDNQKDKLLEEY 1727

Query: 863  QNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKK 922
              ++      + + + L +  N  D   S+  K+  + + L      I  E+   +   +
Sbjct: 1728 SIMK------RTNESKLKDLRNELD---SKIIKFDKERKLLNEGSDNIAQEYSEKVTSLE 1778

Query: 923  KEIEDLEIEFN---TQIESAIRDKK-VLNEK---YEKNIEYVTQLEAQLQEYKNNIE--- 972
            +E+ + +I  +   +++E  I+ K   L EK    +K +E + +LE+ L +YK ++E   
Sbjct: 1779 EELRNQKIYSDDKISELEENIKSKNNALTEKSNLLQKRLEEIKELESTLSKYKADLEATM 1838

Query: 973  -NLNMNVEELNKMNLELIDKHVQ-KQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQ 1030
             N ++  +E   +  EL  K  + K+  +     E  I EI      LK +  E   L  
Sbjct: 1839 KNSDLKNDEFENVCKELSVKENEIKKIEEILSSKEDLIAEIESQKDNLKDELNEKSLLLD 1898

Query: 1031 KINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDD 1090
            K  +   ++   V   +  L +  T+ +N+++ M   +K+L+  ++  E+L++ +    +
Sbjct: 1899 KKESQLEAFQEDVEVQKENLQKKITEYDNLQKLMSLDNKKLVKCEKQIEDLELKLESSSN 1958

Query: 1091 QIKEL--KETKLTFEMNIPKTEGMIISSTIEPMS-DDANNVDX--------XXXXXXXXX 1139
             +KE   K  KL FE    K         I+ +  D +NN D                  
Sbjct: 1959 HLKEQEGKYEKLEFESGENKKLISEKDELIQTLQLDISNNKDEIQKLSDKISTLQNNSEN 2018

Query: 1140 XXLKVQEEEEFIQE-RSVLQEQSAKLNT------ELQECYTKIIQ----LETLNTELTGH 1188
              L ++E+E+ + E  S LQE+ A++ T      +L+E   K ++    L+  +  L   
Sbjct: 2019 TELTLEEKEKMVDELNSKLQEKEAQVETLELDLNKLKETLDKELESSSELQIAHDNLRDE 2078

Query: 1189 DVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWK--QHLAQR 1246
            +++ +++I +LK K++    ++  ++  + E+  +I    +    +  ++ K  + L+ +
Sbjct: 2079 NIIQKQKITELKVKIDDSEKDSQVIIDNMKEMEENIMDLRNDLSSKTIQIEKVNEDLSSK 2138

Query: 1247 EADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHL 1306
             ++ ++   +L  + + ++S   +L+ S + S  E+ +     +++  L+ +L+ K E+L
Sbjct: 2139 NSEIEQLNKKLAEKCAEYDSIKSELVASSKLSESEKNDMKQLSDEINELKEQLELKNENL 2198

Query: 1307 R----------NLQEKYADVI----NQIEILRSEIED-EKVAFXXXXXXXXXXXXXXXXD 1351
            +          N  +KY D +    N I  + S+I + +K                   D
Sbjct: 2199 KKVTSDLQIANNTSDKYNDELKVANNTIREIESKIPNLQKQLDLKEIEYNDTLSSKKDLD 2258

Query: 1352 LRTENQSYK-QMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLE 1410
             + +N S + ++  + + ++ +E   L+K               + D    + E      
Sbjct: 2259 KKLDNFSKESEILSKEVKSLKKEKLDLEKEKNDLIVELDKYKNDIIDLNNTLKENEKNGS 2318

Query: 1411 LKDSEIY---QKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMH 1467
              ++EI     K   Y + ++Q N+E   +   +       +D     +SE+  L  K+ 
Sbjct: 2319 EVETEIIGLKDKIEFYKLNVSQLNEEKGKLESDIKTLVGERDDKLKSSQSEIIELTNKL- 2377

Query: 1468 ENANHYETMQKESEIERVKLIEELNVKITESVS-LNKQVAELNKALEEEVAKTNEMQTAL 1526
            E+        +ES++E   L  +L+ +I +S+   N+ V   NK    E++    M   L
Sbjct: 2378 ESFKDISVAYEESKVESDGLKNKLS-EIEKSLEESNENVDSANK----EISDLKVMNDKL 2432

Query: 1527 ENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKEL 1580
            ++  +E   L D+   L+N    ++ KIQ  ++   + +  + E+   ++ +E+
Sbjct: 2433 QSHNLE---LEDKFQQLKNDTTETNRKIQ-DINKLKEEESSKAEEKIRSLTEEI 2482



 Score =  171 bits (417), Expect = 1e-40
 Identities = 279/1336 (20%), Positives = 565/1336 (42%), Gaps = 125/1336 (9%)

Query: 305  EEKTEIEEKGSLEIANMTELTKKI-ELLEHLNCQIRQTNKELENKLATMGTESKAVSSPS 363
            + K+++E K  L I  +    K++ E  ++    + + NKEL N    +  E + +    
Sbjct: 800  QNKSDLE-KCKLNIEKLENELKEVKERKDNAENGVNKMNKELSN----LSKEKEQLRIEQ 854

Query: 364  KKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKIN---KN-EIAKLEMVIQSLNK 419
             K    I  +      SK+K  ++Q    T  Q TD + N   KN E+  L      L K
Sbjct: 855  GKLEKKIQEQISVYEDSKIK--FNQELESTEKQITDLQSNLESKNTELDNLNKEKSGLMK 912

Query: 420  DLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTN-TEDVNEI 478
            +L + +      D                  +LQ E   +     LI +  N T +++ +
Sbjct: 913  ELTEWKAKFKSHDALVPKLTEKLKSLANSYKELQTERDNYSS--QLIEINKNKTSELSSL 970

Query: 479  AKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLK 538
            ++    LK E  D+I D   K LI K+   E QIT+             K+    K KL 
Sbjct: 971  SESISNLKIE-KDKILDEKSK-LINKVSELESQITE-----------NCKIFEEEKEKLI 1017

Query: 539  QMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDV 598
              +  ++    V D N+++  L  +    S+   EL +   NL   L   DS        
Sbjct: 1018 LSKDELEEL--VIDLNEQLKELETQKETTSKNADELNKSIANLNTQLKQKDS-------- 1067

Query: 599  YKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSE 658
              K+IE+E L E     ++  ESQ  +L+ ++  L ++   V+    ++ +L+++   +E
Sbjct: 1068 --KLIELEELVEVTKNNLNDSESQVSNLIAKISELDEENKSVK---LEVEKLENE--ITE 1120

Query: 659  IKSVH--LEEQIDALSASKKELALVIENLKLD----KEQLYGTIKD---LENDKEDIMNK 709
            IK+ H   +++ D L     E  L++++ K +    K +   T+ D   LEN ++    K
Sbjct: 1121 IKNSHKSAQKETDTLQTKLDETELLLQSSKEEILSLKNEYSSTLSDKENLENSEKKSSEK 1180

Query: 710  LQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQT----QFG--IDAKIQERDLY 763
            ++   +   +L ++ E ++AE  S        EE+ K       Q+G  I +   E+D  
Sbjct: 1181 IEELEKNFSNLQEQFENITAENKSLKEECSGTEEKFKDVNEKLDQYGETISSLSDEKDKL 1240

Query: 764  ---IENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQE 820
               I++ E  +S    ++  + E I ++E  +  LE K   + S L + +   SE     
Sbjct: 1241 NGIIDDKEKIISNLNEKLESISEDIDIIEKAKNLLEEKLATMTSELNDSENGSSELRSLY 1300

Query: 821  DELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALV 880
            D L      L   +      L E+E+++  L +  +ILLE+ + ++ S++D  +  + L 
Sbjct: 1301 DSLKIEFEELQKTNSDKSANLKELENKHTSLTETQEILLEDKKKMESSINDYVKIKDDLE 1360

Query: 881  EK----ANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEI-EFNTQ 935
            ++     N+ ++ E +  K +  L +  S++K +  EH    ++K+ EI   EI +   Q
Sbjct: 1361 KEKEDLLNKYNVLEDKKDKLEIILEENNSSIKVL--EHSIDALKKENEIYKNEIHDMKLQ 1418

Query: 936  IESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQK 995
            +ES+  + K    + EK I   ++L+ +  + KN+ E   +   E+   NL L     +K
Sbjct: 1419 MESSNSEYKNKAGEQEKKI---SRLKEECNKLKNSYEE-KIEKLEVESKNLSLGHDTEKK 1474

Query: 996  QQTQSPDYTEQYINEINKL-----NALLKQKD---EEIIALNQKINNAQVSYMSMVSDYE 1047
            Q        +Q I  I K        L  QK+   +E+  L  +  N++  Y+  + +++
Sbjct: 1475 QFEDKITSLKQEIISIEKSKKQDEKVLKNQKNTLQKELEELKDQFTNSENEYIKKLDNFQ 1534

Query: 1048 SKL-----------AQFTTKLENMEEEMQRVSKQLL----DSKQHNEELQILVREQDDQI 1092
            +++           A   +K+E ++ ++ +  ++ L     +K+H  +++++ +  + Q 
Sbjct: 1535 NEINSVRKEKLDIEAVLNSKIETLKADLSKSEEKSLILEKSNKEHLIKMEVIQKSLEKQN 1594

Query: 1093 KELK---ETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEE 1149
            KEL      K T  MN+   E   +   I    D   N+             ++V+  ++
Sbjct: 1595 KELDILGNEKDTLTMNL-NNEIKGLKEEINSKVDQIGNLKTELNTVSENMEDIQVR-YDQ 1652

Query: 1150 FIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTE 1209
              +E+S + ++  +   +L+E ++ I  L +    L    +   E+   LK + E++   
Sbjct: 1653 LKEEKSEISDKLIESEEKLKENFSSISDLNSSVISLEASIISKDEEYTLLKKEFEEVKIS 1712

Query: 1210 NDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYE 1269
               L +   +L    S        ++ +L +  L  +   F K    L         +Y 
Sbjct: 1713 KQELDNQKDKLLEEYSIMKRTNESKLKDL-RNELDSKIIKFDKERKLLNEGSDNIAQEYS 1771

Query: 1270 QLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHL---RNLQEKYADVINQIEILRSE 1326
            + + S++   + +  KI + ++++ L+  ++ K   L    NL +K  + I ++E   S+
Sbjct: 1772 EKVTSLEEELRNQ--KIYSDDKISELEENIKSKNNALTEKSNLLQKRLEEIKELESTLSK 1829

Query: 1327 IEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEE-NAQLKKSSXXXX 1385
             + +  A                 +L  +    K+++E  IL+  E+  A+++       
Sbjct: 1830 YKADLEATMKNSDLKNDEFENVCKELSVKENEIKKIEE--ILSSKEDLIAEIESQKDNLK 1887

Query: 1386 XXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYE 1445
                     ++  E+++      +E++   + +K  EY     Q+    +N  ++LV+ E
Sbjct: 1888 DELNEKSLLLDKKESQLEAFQEDVEVQKENLQKKITEY--DNLQKLMSLDN--KKLVKCE 1943

Query: 1446 KRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKI-TESVSLNKQ 1504
            K+IEDL  + ES    L+    E    YE ++ ES  E  KLI E +  I T  + ++  
Sbjct: 1944 KQIEDLELKLESSSNHLK----EQEGKYEKLEFESG-ENKKLISEKDELIQTLQLDISNN 1998

Query: 1505 VAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDT 1564
              E+ K  +    K + +Q   EN E+ +      +  L + ++   ++++      +  
Sbjct: 1999 KDEIQKLSD----KISTLQNNSENTELTLEEKEKMVDELNSKLQEKEAQVETLELDLNKL 2054

Query: 1565 KQGRDEQLDNTMNKEL 1580
            K+  D++L+++   ++
Sbjct: 2055 KETLDKELESSSELQI 2070



 Score =  169 bits (411), Expect = 5e-40
 Identities = 327/1541 (21%), Positives = 666/1541 (43%), Gaps = 173/1541 (11%)

Query: 90   ISESLANT---LKQKEILMEKIKQYKELSKRS---STTIVRXXXXXXXXXXXXXXXQLGD 143
            +++S+AN    LKQK+  + ++++  E++K +   S + V                   +
Sbjct: 1051 LNKSIANLNTQLKQKDSKLIELEELVEVTKNNLNDSESQVSNLIAKISELDEENKSVKLE 1110

Query: 144  VTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKI-NEKDQIIEAKNK--ATTXXXXXX 200
            V  L N I E  N+    Q +   ++T + + +  + + K++I+  KN+  +T       
Sbjct: 1111 VEKLENEITEIKNSHKSAQKETDTLQTKLDETELLLQSSKEEILSLKNEYSSTLSDKENL 1170

Query: 201  XXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRL------LKDIESK----DVRI 250
                       E+ ++  + +QE F  + AE K  K+         KD+  K       I
Sbjct: 1171 ENSEKKSSEKIEELEKNFSNLQEQFENITAENKSLKEECSGTEEKFKDVNEKLDQYGETI 1230

Query: 251  SSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEI 310
            SSL +    L     +     S L ++LE               L ++ +     E  + 
Sbjct: 1231 SSLSDEKDKLNGIIDDKEKIISNLNEKLESISEDIDIIEKAKNLL-EEKLATMTSELND- 1288

Query: 311  EEKGSLEIANMTELTK-KIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPL 369
             E GS E+ ++ +  K + E L+  N       KELENK  ++ TE++ +    KK    
Sbjct: 1289 SENGSSELRSLYDSLKIEFEELQKTNSDKSANLKELENKHTSL-TETQEILLEDKK---- 1343

Query: 370  ISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVIS 429
               +S  N   K+K    +   + LN+    +  K+   KLE++++  N  +   E+ I 
Sbjct: 1344 -KMESSINDYVKIKDDLEKEKEDLLNKYNVLEDKKD---KLEIILEENNSSIKVLEHSID 1399

Query: 430  EKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQEL 489
                               +     E++ +  G     +    E+ N++    E+  ++L
Sbjct: 1400 ALKKENEIYKNEIHDMKLQMESSNSEYK-NKAGEQEKKISRLKEECNKLKNSYEEKIEKL 1458

Query: 490  NDEIKDVNVKDLIEKLKSAEEQITQLNDEI---DAANKNMIKVKSNHKLKL-KQMQKTID 545
              E K++++    EK K  E++IT L  EI   + + K   KV  N K  L K++++  D
Sbjct: 1459 EVESKNLSLGHDTEK-KQFEDKITSLKQEIISIEKSKKQDEKVLKNQKNTLQKELEELKD 1517

Query: 546  NFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEM 605
             F+   +S  E ++   +L +   ++  + +EK  L +  V       +++D        
Sbjct: 1518 QFT---NSENEYIK---KLDNFQNEINSVRKEK--LDIEAVLNSKIETLKAD-------- 1561

Query: 606  ENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVC----SEIKS 661
              L+++  K++ L +S K  L++ + ++Q+  ++ ++K  DI   + D +     +EIK 
Sbjct: 1562 --LSKSEEKSLILEKSNKEHLIK-MEVIQKSLEK-QNKELDILGNEKDTLTMNLNNEIKG 1617

Query: 662  V--HLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMD 719
            +   +  ++D +   K EL  V EN++ D +  Y  +K+ +++  D + + +  ++EN  
Sbjct: 1618 LKEEINSKVDQIGNLKTELNTVSENME-DIQVRYDQLKEEKSEISDKLIESEEKLKENFS 1676

Query: 720  LTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRIC 779
                L        + +++K   EE + ++ +F  + KI +++L  +N + +L +  S + 
Sbjct: 1677 SISDLNSSVISLEASIISK--DEEYTLLKKEFE-EVKISKQEL--DNQKDKLLEEYSIMK 1731

Query: 780  RLEESIAVMEDRRYSLERKA---DQLGSYLQEKQ----KAYSE-YTIQEDELVNRLAVLM 831
            R  ES   ++D R  L+ K    D+    L E      + YSE  T  E+EL N+   + 
Sbjct: 1732 RTNES--KLKDLRNELDSKIIKFDKERKLLNEGSDNIAQEYSEKVTSLEEELRNQK--IY 1787

Query: 832  DHDRVVEKQLLEIEHENKELQKKNQIL---LEENQNLQISLSDMQQHYNALVEKANRTDL 888
              D++ E +   I+ +N  L +K+ +L   LEE + L+ +LS  +    A ++ +   DL
Sbjct: 1788 SDDKISELEE-NIKSKNNALTEKSNLLQKRLEEIKELESTLSKYKADLEATMKNS---DL 1843

Query: 889  AESESTKYQTQLRDLESNLKRITH---EHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKV 945
               E      +L   E+ +K+I       + LI + + + ++L+ E N +  S + DKK 
Sbjct: 1844 KNDEFENVCKELSVKENEIKKIEEILSSKEDLIAEIESQKDNLKDELNEK--SLLLDKKE 1901

Query: 946  LN-EKYEKNIEYVTQ-LEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQT----- 998
               E +++++E   + L+ ++ EY N  + ++++ ++L K   ++ D  ++ + +     
Sbjct: 1902 SQLEAFQEDVEVQKENLQKKITEYDNLQKLMSLDNKKLVKCEKQIEDLELKLESSSNHLK 1961

Query: 999  -QSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKL 1057
             Q   Y E+   E  +   L+ +KDE I  L   I+N +   +  +SD  S L   +   
Sbjct: 1962 EQEGKY-EKLEFESGENKKLISEKDELIQTLQLDISNNK-DEIQKLSDKISTLQNNSENT 2019

Query: 1058 ENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISST 1117
            E   EE +++  +L +SK   +E Q+   E D  + +LKET L  E+    +E  I    
Sbjct: 2020 ELTLEEKEKMVDEL-NSKLQEKEAQVETLELD--LNKLKET-LDKELE-SSSELQIAHDN 2074

Query: 1118 IEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQ 1177
            +     D N +                ++ +  I     ++E    L  +L    +K IQ
Sbjct: 2075 LR----DENIIQKQKITELKVKIDDSEKDSQVIIDNMKEMEENIMDLRNDLS---SKTIQ 2127

Query: 1178 LETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTV---AELRSSISSAVDQRGFE 1234
            +E +N +L+  +     +I QL  KL +   E D++ S +   ++L  S  + + Q   E
Sbjct: 2128 IEKVNEDLSSKN----SEIEQLNKKLAEKCAEYDSIKSELVASSKLSESEKNDMKQLSDE 2183

Query: 1235 IAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTS 1294
            I EL K+ L  +  + +K   +L++  +  + KY   L    ++ +E  +KI  +++   
Sbjct: 2184 INEL-KEQLELKNENLKKVTSDLQIANNTSD-KYNDELKVANNTIREIESKIPNLQKQLD 2241

Query: 1295 LQN-KLQDKEEHLRNLQEKYADVINQIEILRSEIED---EKVAFXXXXXXXXXXXXXXXX 1350
            L+  +  D     ++L +K  +   + EIL  E++    EK+                  
Sbjct: 2242 LKEIEYNDTLSSKKDLDKKLDNFSKESEILSKEVKSLKKEKLDLEKEKNDLIVELDKYKN 2301

Query: 1351 DLRTENQSYKQMQEQSI-----------------LNINEENAQLKKSSXXXXXXXXXXXX 1393
            D+   N + K+ ++                    LN+++ N +  K              
Sbjct: 2302 DIIDLNNTLKENEKNGSEVETEIIGLKDKIEFYKLNVSQLNEEKGKLESDIKTLVGERDD 2361

Query: 1394 RVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTY 1453
            ++  ++++++ELT++LE           + ++   +   E + ++ +L E EK +E+   
Sbjct: 2362 KLKSSQSEIIELTNKLE--------SFKDISVAYEESKVESDGLKNKLSEIEKSLEESNE 2413

Query: 1454 EKES-ELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKAL 1512
              +S    I  LK+  +      ++ E + +++K          ++   N+++ ++NK  
Sbjct: 2414 NVDSANKEISDLKVMNDKLQSHNLELEDKFQQLK---------NDTTETNRKIQDINKLK 2464

Query: 1513 EEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSK 1553
            EEE +K  E          +I +L +EI  L+N  + + SK
Sbjct: 2465 EEESSKAEE----------KIRSLTEEIEKLKNDFKKNESK 2495



 Score =  144 bits (348), Expect = 2e-32
 Identities = 217/987 (21%), Positives = 431/987 (43%), Gaps = 99/987 (10%)

Query: 637  YDEVEDKLADISQLQSDQV---CSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLY 693
            +D  ++ +A IS    D++   CS++K   L +   +      EL L +E L    +   
Sbjct: 688  HDPEQESIAKISFETFDELQRECSKLKG-ELNDMFVSKGDVINELELKVEELSNKSKNSI 746

Query: 694  GTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGI 753
               + ++N+ + + N  +    E   ++ KL+++  E+  E L  +  E+  K++     
Sbjct: 747  SDYESIKNEYDILKNNYEEKEGEFESVSKKLDELLTER--EKLNSVTSEQLKKLEQN--- 801

Query: 754  DAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAY 813
             + +++  L IE +E+EL + K R    E  +  M     +L ++ +QL     + +K  
Sbjct: 802  KSDLEKCKLNIEKLENELKEVKERKDNAENGVNKMNKELSNLSKEKEQLRIEQGKLEKKI 861

Query: 814  SE-YTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDM 872
             E  ++ ED  +     L   ++ +      +E +N EL   N    +E   L   L++ 
Sbjct: 862  QEQISVYEDSKIKFNQELESTEKQITDLQSNLESKNTELDNLN----KEKSGLMKELTEW 917

Query: 873  Q---QHYNALVEKANRTDLAESESTK-YQTQLRDLESNLKRITHEHQTLIVQKKKEIEDL 928
            +   + ++ALV K      + + S K  QT+  +  S L  I     + +    + I +L
Sbjct: 918  KAKFKSHDALVPKLTEKLKSLANSYKELQTERDNYSSQLIEINKNKTSELSSLSESISNL 977

Query: 929  EIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQE----YKNNIENLNMNVEELNKM 984
            +IE         +D K+L+EK  K I  V++LE+Q+ E    ++   E L ++ +EL ++
Sbjct: 978  KIE---------KD-KILDEK-SKLINKVSELESQITENCKIFEEEKEKLILSKDELEEL 1026

Query: 985  NLELIDKHVQKQQTQSPDYTEQYINEINK----LNALLKQKDEEIIALNQKI----NNAQ 1036
             ++L ++ +++ +TQ  + T +  +E+NK    LN  LKQKD ++I L + +    NN  
Sbjct: 1027 VIDL-NEQLKELETQK-ETTSKNADELNKSIANLNTQLKQKDSKLIELEELVEVTKNNLN 1084

Query: 1037 VSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELK 1096
             S  S VS+  +K+++   + ++++ E++++  ++ + K  ++  Q   +E D    +L 
Sbjct: 1085 DS-ESQVSNLIAKISELDEENKSVKLEVEKLENEITEIKNSHKSAQ---KETDTLQTKLD 1140

Query: 1097 ETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLK-----VQEE-EEF 1150
            ET+L  + +  K E + + +       D  N++            L+     +QE+ E  
Sbjct: 1141 ETELLLQSS--KEEILSLKNEYSSTLSDKENLENSEKKSSEKIEELEKNFSNLQEQFENI 1198

Query: 1151 IQERSVLQEQSAKLNTELQECYTKIIQL-ETLNTELTGHDVVN------QEQINQLKSKL 1203
              E   L+E+ +    + ++   K+ Q  ET+++     D +N      ++ I+ L  KL
Sbjct: 1199 TAENKSLKEECSGTEEKFKDVNEKLDQYGETISSLSDEKDKLNGIIDDKEKIISNLNEKL 1258

Query: 1204 EQLNTEND------NLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHEL 1257
            E ++ + D      NLL       +S  +  +    E+  L+     + E + QKT  + 
Sbjct: 1259 ESISEDIDIIEKAKNLLEEKLATMTSELNDSENGSSELRSLYDSLKIEFE-ELQKTNSDK 1317

Query: 1258 RVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVI 1317
               L   E+K+  L ++ +   +++     ++     +++ L+ ++E L N      D  
Sbjct: 1318 SANLKELENKHTSLTETQEILLEDKKKMESSINDYVKIKDDLEKEKEDLLNKYNVLEDKK 1377

Query: 1318 NQIEILRSE-------IEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQM---QEQSI 1367
            +++EI+  E       +E    A                  + + N  YK     QE+ I
Sbjct: 1378 DKLEIILEENNSSIKVLEHSIDALKKENEIYKNEIHDMKLQMESSNSEYKNKAGEQEKKI 1437

Query: 1368 LNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELK---DSEIYQKTHEYT 1424
              + EE  +LK S                + E+K L L H  E K   D     K    +
Sbjct: 1438 SRLKEECNKLKNSYEEKIEKL--------EVESKNLSLGHDTEKKQFEDKITSLKQEIIS 1489

Query: 1425 ITLTQRNDEFENVRQQLVEYEKRIEDLTYE-KESELAILRLKMHENANHYETMQKES-EI 1482
            I  +++ DE + ++ Q    +K +E+L  +   SE   ++ K+    N   +++KE  +I
Sbjct: 1490 IEKSKKQDE-KVLKNQKNTLQKELEELKDQFTNSENEYIK-KLDNFQNEINSVRKEKLDI 1547

Query: 1483 ERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDE--- 1539
            E V   +   +K   S S  K +  L K+ +E + K   +Q +LE Q  E+  L +E   
Sbjct: 1548 EAVLNSKIETLKADLSKSEEKSLI-LEKSNKEHLIKMEVIQKSLEKQNKELDILGNEKDT 1606

Query: 1540 -ITNLQNMVRASSSKIQKHVSFASDTK 1565
               NL N ++    +I   V    + K
Sbjct: 1607 LTMNLNNEIKGLKEEINSKVDQIGNLK 1633



 Score =  109 bits (263), Expect = 5e-22
 Identities = 232/1087 (21%), Positives = 464/1087 (42%), Gaps = 117/1087 (10%)

Query: 92   ESLANTLKQKEILMEKIKQYKE-LSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNT 150
            E    +LKQ+ I +EK K+  E + K    T+ +                +  + +  N 
Sbjct: 1477 EDKITSLKQEIISIEKSKKQDEKVLKNQKNTLQKELEELKDQFTNSENEYIKKLDNFQNE 1536

Query: 151  IKE-KDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXX 209
            I   +   L +  V    +ET   DL  K  EK  I+E  NK                  
Sbjct: 1537 INSVRKEKLDIEAVLNSKIETLKADLS-KSEEKSLILEKSNKEHLIKMEVIQKSLEKQNK 1595

Query: 210  XXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISL 269
              +    +   +  N        K+E    +  I +    ++++ E  + ++    ++  
Sbjct: 1596 ELDILGNEKDTLTMNLNNEIKGLKEEINSKVDQIGNLKTELNTVSENMEDIQVRYDQLKE 1655

Query: 270  EHSKLAQELEQXXXXXXXXXXXXXXLAKQ--SIEPSCEEKTEI-----EEKGSLEIANMT 322
            E S+++ +L +              L     S+E S   K E      +E   ++I+   
Sbjct: 1656 EKSEISDKLIESEEKLKENFSSISDLNSSVISLEASIISKDEEYTLLKKEFEEVKISKQE 1715

Query: 323  ELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKM 382
               +K +LLE  +  +++TN   E+KL  +  E  +      K   L++  S  N A + 
Sbjct: 1716 LDNQKDKLLEEYSI-MKRTN---ESKLKDLRNELDSKIIKFDKERKLLNEGSD-NIAQEY 1770

Query: 383  KSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEK-DTXXXXXXXX 441
                + L  E  NQ   K  + ++I++LE  I+S N  L +K  ++ ++ +         
Sbjct: 1771 SEKVTSLEEELRNQ---KIYSDDKISELEENIKSKNNALTEKSNLLQKRLEEIKELESTL 1827

Query: 442  XXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQL--KQELNDEIKDV--N 497
               K  L A ++    ++ E  ++    +  E  NEI K++E L  K++L  EI+    N
Sbjct: 1828 SKYKADLEATMKNSDLKNDEFENVCKELSVKE--NEIKKIEEILSSKEDLIAEIESQKDN 1885

Query: 498  VKD-LIEK---LKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDS 553
            +KD L EK   L   E Q+    ++++   +N+ K  + +    K M  ++DN  K+   
Sbjct: 1886 LKDELNEKSLLLDKKESQLEAFQEDVEVQKENLQKKITEYDNLQKLM--SLDN-KKLVKC 1942

Query: 554  NKEI----VRLTEELHHLSQ---KVAELEEEKGNLQLHLVDYDSG-RMIESDVYKKMIEM 605
             K+I    ++L    +HL +   K  +LE E G  +  + + D   + ++ D+     E+
Sbjct: 1943 EKQIEDLELKLESSSNHLKEQEGKYEKLEFESGENKKLISEKDELIQTLQLDISNNKDEI 2002

Query: 606  ENLAE------TRLKAISLLESQKFDLVQELHI-LQQKYDEVEDKLADISQLQSD----- 653
            + L++         +   L   +K  +V EL+  LQ+K  +VE    D+++L+       
Sbjct: 2003 QKLSDKISTLQNNSENTELTLEEKEKMVDELNSKLQEKEAQVETLELDLNKLKETLDKEL 2062

Query: 654  QVCSEIKSVHLEEQIDALSASKK--ELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQ 711
            +  SE++  H   + + +   +K  EL + I++ + D + +   +K++E +  D+ N L 
Sbjct: 2063 ESSSELQIAHDNLRDENIIQKQKITELKVKIDDSEKDSQVIIDNMKEMEENIMDLRNDLS 2122

Query: 712  N---YIQE-NMDLTDK------LEKMSAEKI-------SELLA--KINHEEQSKI-QTQF 751
            +    I++ N DL+ K      L K  AEK        SEL+A  K++  E++ + Q   
Sbjct: 2123 SKTIQIEKVNEDLSSKNSEIEQLNKKLAEKCAEYDSIKSELVASSKLSESEKNDMKQLSD 2182

Query: 752  GIDAKIQERDLYIENIE---SELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQE 808
             I+   ++ +L  EN++   S+L    +   +  + + V  +    +E K   L   L  
Sbjct: 2183 EINELKEQLELKNENLKKVTSDLQIANNTSDKYNDELKVANNTIREIESKIPNLQKQLDL 2242

Query: 809  KQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQK-KNQILLE----ENQ 863
            K+  Y++    + +L  +L        ++ K++  ++ E  +L+K KN +++E    +N 
Sbjct: 2243 KEIEYNDTLSSKKDLDKKLDNFSKESEILSKEVKSLKKEKLDLEKEKNDLIVELDKYKND 2302

Query: 864  NLQISLSDMQQHYNA------LVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTL 917
             + ++ +  +   N       ++   ++ +  +   ++   +   LES++K +  E    
Sbjct: 2303 IIDLNNTLKENEKNGSEVETEIIGLKDKIEFYKLNVSQLNEEKGKLESDIKTLVGERDDK 2362

Query: 918  IVQKKKEIEDL--EIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLN 975
            +   + EI +L  ++E    I  A  + KV ++  +  +   +++E  L+E   N+++ N
Sbjct: 2363 LKSSQSEIIELTNKLESFKDISVAYEESKVESDGLKNKL---SEIEKSLEESNENVDSAN 2419

Query: 976  MNVEELNKMNLELIDKHVQ---KQQTQSPDYTE--QYINEINKLNALLKQKDEEII-ALN 1029
              + +L  MN +L   +++   K Q    D TE  + I +INKL      K EE I +L 
Sbjct: 2420 KEISDLKVMNDKLQSHNLELEDKFQQLKNDTTETNRKIQDINKLKEEESSKAEEKIRSLT 2479

Query: 1030 QKINNAQVSY----------------MSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLD 1073
            ++I   +  +                M +VSD + K +++  KLE +  E+   S +  +
Sbjct: 2480 EEIEKLKNDFKKNESKAPDTSEIDDLMLLVSDLDEKNSKYKAKLEELGVELS--SDEETE 2537

Query: 1074 SKQHNEE 1080
            S   +EE
Sbjct: 2538 SDDTDEE 2544



 Score = 41.1 bits (92), Expect = 0.25
 Identities = 36/139 (25%), Positives = 68/139 (48%), Gaps = 11/139 (7%)

Query: 1431 NDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHEN---ANHYETMQKESEIERVKL 1487
            ND F +    + E E ++E+L+ + ++ ++      +E     N+YE  +KE E E V  
Sbjct: 718  NDMFVSKGDVINELELKVEELSNKSKNSISDYESIKNEYDILKNNYE--EKEGEFESVS- 774

Query: 1488 IEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMV 1547
             ++L+  +TE   LN   +E  K LE+  +   + +  +E  E E+  + +   N +N V
Sbjct: 775  -KKLDELLTEREKLNSVTSEQLKKLEQNKSDLEKCKLNIEKLENELKEVKERKDNAENGV 833

Query: 1548 RASSSKIQKHVSFASDTKQ 1566
                +K+ K +S  S  K+
Sbjct: 834  ----NKMNKELSNLSKEKE 848


>UniRef50_A2FSZ8 Cluster: Viral A-type inclusion protein, putative;
            n=1; Trichomonas vaginalis G3|Rep: Viral A-type inclusion
            protein, putative - Trichomonas vaginalis G3
          Length = 4045

 Score =  196 bits (479), Expect = 3e-48
 Identities = 289/1490 (19%), Positives = 632/1490 (42%), Gaps = 124/1490 (8%)

Query: 147  LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXX 206
            L N I+   NAL+  Q + K ++    +  +KI + +QI++ +NK               
Sbjct: 844  LQNDIESITNALNQSQNENKELK----EENQKIEKSNQILQYENKEVKEQKEKLQNQIDD 899

Query: 207  XXXXXEDTKQQMTKMQENFIAMEAEWKDEK---QRLLKDIESK--DVRISSLEEANKLLE 261
                  + + ++ ++ E   ++  E  +++   Q +LKD+E+K  ++    LE   ++ E
Sbjct: 900  LKNQNSNLQNKVDELNEEISSINEEKSNQEKEYQEMLKDLETKLKNLEAERLESNKEITE 959

Query: 262  AARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANM 321
                + + + S ++  L +              L +Q+   + E +    +   L + N 
Sbjct: 960  ILELDTTFDDSTISDHLRKQCEQLKS-------LIEQNKNQNEEIQNLKSQNEDLTVKN- 1011

Query: 322  TELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASK 381
             E+ K++   +   C + +T+++ + ++  +  + + + S         S+K    T ++
Sbjct: 1012 EEMKKELMNNQTTICDLIKTSEDKDKEIDDLKQKIEKLKSEIDN-----SKKQLDTTLTE 1066

Query: 382  MK-SPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXX 440
             K S + +L S+    + DKK       KLE  +Q+L K+  + +  +  K+        
Sbjct: 1067 FKVSNFDELQSQISRNNDDKK-------KLEQKVQNLQKENEEMKIKLENKENERKSLSS 1119

Query: 441  XXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKD 500
                   L  +LQ   + H      I +G   ++++ + + + +L +E+ D+I + N+  
Sbjct: 1120 LESENILLKQKLQNNDKLHQ-----IQIGELQKEIDVLNQTKSKLSKEV-DDITNENIT- 1172

Query: 501  LIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQM---QKTIDNFSKVSDSNKEI 557
            L  ++ +        N+E+      +IK  ++++L+L Q    +  ID  +K+SD   E+
Sbjct: 1173 LKNQINTTFSMSIDENNELKKKLNQLIKENNSYQLQLNQSVPKEDFIDLQNKISDLENEL 1232

Query: 558  ---VRL---TEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAET 611
               V L    E   +L + ++ ++  K ++++   +  + +   ++   KM  ++N  + 
Sbjct: 1233 QNSVSLKDYNESQAYLEKTMSTVDNLKSSVKVAQKELQNMKQTMNNQNTKMTSLQNTLQD 1292

Query: 612  RLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDAL 671
            +   IS L+ +   L  ++  L+ +  +  +K+ +   LQ   + S I++  ++ Q++  
Sbjct: 1293 KDSEISDLKEKNSQLELKIEDLEGEKSKDNEKMKN-KDLQIKLMESTIEN--MKSQLNES 1349

Query: 672  SASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEK 731
             +   E AL+   L+  KE  +  +++ EN     MN  QN   EN  + +   +   + 
Sbjct: 1350 QSLNNEYALLQSTLQ-SKENQFSKLQN-ENVMLQTMN--QNLTNENASMKENHNREIQKL 1405

Query: 732  ISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENI-----ESELSKYKSRICRLEESIA 786
             ++L  K   E+    + Q  +   + ++DL I N+     E+EL     +I  L     
Sbjct: 1406 QNDLQNKEFQEKMINSELQ-KLKESLTQKDLQISNLSRYSNENELKNKNIQIEYLTNENK 1464

Query: 787  VMEDRRYSLE---RKADQ----LGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEK 839
             +++    LE   RK D     + S L+ K+    E       L N +    + +  +E 
Sbjct: 1465 KLKETNLDLESQIRKKDNEINDINSNLKRKENQLQETENTNRNLQNDIKRKQNENNDLEN 1524

Query: 840  QLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLA----ESESTK 895
            ++ +++    + Q  N ++  + +   +   D++     L +K++   L+    ES++ +
Sbjct: 1525 EINKLKDLLSKSQHDNDLVNNDLKRKDLQNRDLENKLKNLKDKSSELQLSLSRMESDNKR 1584

Query: 896  YQTQLRDLESNLKRITHEHQTL---IVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEK 952
               Q+ +LE++LK+    + +L   + +K+ +I +L+ + NT +     +   L  + + 
Sbjct: 1585 KDNQIIELENDLKKSKEINNSLSNDLKRKENQISELQNQQNTDLIKKQNENNDLMNENKS 1644

Query: 953  NIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEIN 1012
              E + + E++     + ++   + + +L K   +L  K V +    S        N+I 
Sbjct: 1645 LKELIAKKESENDSINSELKRRTLQINDLEKEIKDLASKRVDENNDLS--------NQIK 1696

Query: 1013 KLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLL 1072
             +  L+ +K+ E    N  INN      S  +D +  LA+  +++  +  E++R+S +  
Sbjct: 1697 NMKDLISKKETE----NNSINNELRRVNSQNNDLKELLAKKESEINAINNELKRISSENN 1752

Query: 1073 DSKQHNEELQILVREQ----DDQIKELKET--KL----TFEMNIPKTEGMIISSTIEPMS 1122
            D K  N + +   ++Q     +Q+ +LK    KL    T E N  K + +I    I+  S
Sbjct: 1753 DLKDINSKSENNYQDQLKNLKNQLTQLKNENQKLMKSSTEEKN--KLKDLINEKNIQIQS 1810

Query: 1123 DDANNVDXXXXXXXXXXXXLKVQEE-EEFIQERSVLQEQSAKLNTELQECYTKIIQLETL 1181
              + N D              +Q++ +E   + SVL  ++ KL  EL    T+I  L+  
Sbjct: 1811 LQSKNEDLVNNQSKINNKLESIQKDLDEKENQNSVLISENEKLQNELMSSKTEIQTLDQK 1870

Query: 1182 NTELTG-------HDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSS--ISSAVDQRG 1232
             TE          ++     QIN LK KL  L   N+ +     +L+    I SA +Q+ 
Sbjct: 1871 ETEFNDKLREMERNNRSLSSQINDLKEKLNNLTETNEKISDENTKLKQQMKIESANNQKQ 1930

Query: 1233 FEIAELWKQHLAQREADFQKTEHELR-VQLSAFESKYEQLLDSVQSS--TQEETNKIVTM 1289
             +  E  K +  Q E +  K++   +   L   + + EQ ++ ++ S   +EE+  I+  
Sbjct: 1931 LKQLETEKLNRLQEENNKLKSQISKKDSDLQKLKQESEQTINDLKESLLNKEESLSILEK 1990

Query: 1290 ------EQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXX 1343
                  +Q+      + +  + +  +QEK     N    L+++I+  +            
Sbjct: 1991 SADFITKQIDGKSKSINENSQIIEQMQEKIIQKDNATTDLQNKIKQLESQLQQNEKDNDK 2050

Query: 1344 XXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVL 1403
                   +L+      K ++E+ +   NE N+  K  +             +N+ EAK  
Sbjct: 2051 VKQLQT-ELKEHQLKIKNLEEKIVKLNNENNSLQKLINSKDDEKVKQLQNNINENEAKTK 2109

Query: 1404 ELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILR 1463
                Q++   SE     +     + + + + ++ ++++        DL   K SE  I  
Sbjct: 2110 TFEDQIQKLTSE----NNSLRKNINENDSKVKSYQEEIQNLTNEKNDLI--KSSETKIKE 2163

Query: 1464 LKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQ 1523
            L         E  Q+  ++ R K   +L  K  E    NK +++L++ L E   K NE++
Sbjct: 2164 LTESSKNQISELNQRLQDVTR-KSDLDLQKKEMEIQIANKNISDLHQQLLESNQKLNEIK 2222

Query: 1524 TALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLD 1573
                NQ++++    +++T   +++    ++I+  ++ +S   Q    + D
Sbjct: 2223 LQANNQQLQLKQKENDLTTANSIIETLKNEIENTMNKSSILVQNEMNKKD 2272



 Score =  184 bits (447), Expect = 2e-44
 Identities = 311/1531 (20%), Positives = 669/1531 (43%), Gaps = 140/1531 (9%)

Query: 144  VTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKN---KATTXXXXXX 200
            + ++ + I +K+   + +  +++ + +   DL+E + +K+  I A N   K  +      
Sbjct: 1695 IKNMKDLISKKETENNSINNELRRVNSQNNDLKELLAKKESEINAINNELKRISSENNDL 1754

Query: 201  XXXXXXXXXXXEDT----KQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEA 256
                       +D     K Q+T+++     +     +EK +L   I  K+++I SL+  
Sbjct: 1755 KDINSKSENNYQDQLKNLKNQLTQLKNENQKLMKSSTEEKNKLKDLINEKNIQIQSLQSK 1814

Query: 257  NKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXL------AKQSIEPSCEEKTEI 310
            N+ L   + +I+ +   + ++L++              L      +K  I+   +++TE 
Sbjct: 1815 NEDLVNNQSKINNKLESIQKDLDEKENQNSVLISENEKLQNELMSSKTEIQTLDQKETEF 1874

Query: 311  EEKGSLEIANMTELTKKI-ELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPL 369
             +K      N   L+ +I +L E LN  + +TN+++ ++   +  + K  S+ ++K    
Sbjct: 1875 NDKLREMERNNRSLSSQINDLKEKLN-NLTETNEKISDENTKLKQQMKIESANNQKQLKQ 1933

Query: 370  ISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVIS 429
            +  +      ++++   ++L S+   +D+D +  K E    E  I  L + L++KE  +S
Sbjct: 1934 LETEK----LNRLQEENNKLKSQISKKDSDLQKLKQES---EQTINDLKESLLNKEESLS 1986

Query: 430  EKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDV-NEIAKVQEQLKQE 488
              +           GK   I +     +Q  E   +I     T D+ N+I +++ QL+Q 
Sbjct: 1987 ILEKSADFITKQIDGKSKSINENSQIIEQMQE--KIIQKDNATTDLQNKIKQLESQLQQN 2044

Query: 489  L--NDEIKDVN--VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTI 544
               ND++K +   +K+   K+K+ EE+I +LN+E ++  K +I  K + K+K  Q+Q  I
Sbjct: 2045 EKDNDKVKQLQTELKEHQLKIKNLEEKIVKLNNENNSLQK-LINSKDDEKVK--QLQNNI 2101

Query: 545  -DNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKM- 602
             +N +K      +I +LT E + L + + E + +  + Q  + +  + +   +D+ K   
Sbjct: 2102 NENEAKTKTFEDQIQKLTSENNSLRKNINENDSKVKSYQEEIQNLTNEK---NDLIKSSE 2158

Query: 603  IEMENLAETRLKAISLLESQKFDLVQELHI-LQQKYDEVE---DKLADISQ--LQSDQVC 656
             +++ L E+    IS L  +  D+ ++  + LQ+K  E++     ++D+ Q  L+S+Q  
Sbjct: 2159 TKIKELTESSKNQISELNQRLQDVTRKSDLDLQKKEMEIQIANKNISDLHQQLLESNQKL 2218

Query: 657  SEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQE 716
            +EIK   L+     L   +KE  L   N           I+ L+N+ E+ MNK    +Q 
Sbjct: 2219 NEIK---LQANNQQLQLKQKENDLTTAN---------SIIETLKNEIENTMNKSSILVQN 2266

Query: 717  NMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKS 776
             M+  D++ +   E++S L  + N EE SK+Q       ++      I++   E++  K 
Sbjct: 2267 EMNKKDEIIQNLQEQLSNLKQETN-EEISKLQNDKNNQTELLN---LIKSKNDEINNLKE 2322

Query: 777  RICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRV 836
             I R ++   +M+ +RY    + + L     + Q   S        L+  L  + +  ++
Sbjct: 2323 -INRQKDQ-QIMDLKRYE---QTELLNLSNNDDQNRSSSIVYNSSTLMKSLRQVKEDSQI 2377

Query: 837  VEK----QL----LEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDL 888
             EK    QL    ++ + E K LQ KN    E+ ++L+  ++++  + N + E++   ++
Sbjct: 2378 REKFIDDQLKSLSMQKDEEIKNLQNKNSEKDEKIRDLEKQINNLSDNSNHIKEESMINEV 2437

Query: 889  A-ESESTKYQTQLRDLESNLKRITHEHQTL---IVQKKKEIEDLEIEFNTQIESAIRD-K 943
              +S       ++  ++++  ++  E+Q L   I +  K+I+D E E N  ++  I+   
Sbjct: 2438 KLKSNIDSMNDKILQMQNDSNQLFKENQNLRNSIDKLNKQIKDFEQE-NESLKQTIQSFT 2496

Query: 944  KVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDY 1003
            K+ NE  E+N +   +    +     N  NL +  ++ NK  +++++     + ++  D 
Sbjct: 2497 KLNNELTEENEKIYKKYNDLINNNAVNENNLQVMKDQNNKNQIKILELTRNLEMSKFND- 2555

Query: 1004 TEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEE 1063
             +Q  ++IN+L   L +K E++I L Q     Q++  S   D +  L Q   ++  + E 
Sbjct: 2556 -DQNKDKINELETDLAEK-EKLIKLLQN----QLTVSSSDKDMKQILQQKDEEIRKLNEN 2609

Query: 1064 MQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSD 1123
              ++       ++  EE      E  +Q+KE +  +++ E    K E  I +  I     
Sbjct: 2610 NGKIKVLQNQIEKMKEENNSKTNELLNQLKESENKRISLEAEKKKLEIEISNLNI----- 2664

Query: 1124 DANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNT 1183
            D NN+             +   + +E  ++R+++ +   K   +L    TK   L+  NT
Sbjct: 2665 DDNNLKLMEQKMKEMSNVINKLQSQESDKDRTIMNQ--TKQIKKLGSIMTKAKSLKAENT 2722

Query: 1184 ELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELR-SSISSAVDQRGFEIAELWKQ- 1241
             L     ++  + ++ +     LN+ +  + S   + + S +   V +   E  +L  + 
Sbjct: 2723 LLRSQ--ISDLESSKTEISSASLNSSSPQMSSLSQKKKISRLEKQVTELLQENEDLKMEI 2780

Query: 1242 -HLAQREADFQKTEHE-LRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQ----VTSL 1295
             H +  + +    E+E L++++ + E++  ++ + +++  +    K+  ME+    ++S 
Sbjct: 2781 IHKSTSDENLDSLENEKLQLRIKSLETQLNKMKE-IENENKNLKTKVSFMEENSKKLSSE 2839

Query: 1296 QNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTE 1355
               L  K   ++        +    EIL    ++ +  +                 L T 
Sbjct: 2840 IESLIKKNGEMKINLVSLKSIKENFEILEKSSKEREAEYSKYRASQEKKVNDLQTKLSTL 2899

Query: 1356 NQSYKQMQEQSILNINE-----ENAQLKKS----SXXXXXXXXXXXXRVNDAEAKVLELT 1406
               Y  ++ ++ +N+ E      N +LK++    S             +N   ++  +L+
Sbjct: 2900 ENDYSDLKNENEMNVLEIQKITNNLKLKENQLQRSLDNDKTMDSLQATLNTKTSENQKLS 2959

Query: 1407 HQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKM 1466
             +L L+++EI     E       + +  + +       +K  +DL  ++ +++  L  ++
Sbjct: 2960 TELVLRNNEIKDLKDEIGKVNNDKEELMKIINVNNTLVQKLQKDLL-DRNNQIEFLNKEI 3018

Query: 1467 HENANHYETMQKESEIERVKLIEELNVKITESV-SLNKQVAELNKALE---EEV------ 1516
             EN   ++    ES   ++  +  +  ++ E++ SL+     L   +E   +E+      
Sbjct: 3019 QENKEEFDQKINESNT-KIDELNNIIKQMKETIKSLSNDKDNLKSTIEGNEDEIHRIANK 3077

Query: 1517 --AKTNEMQTAL-ENQEI--EIVTLNDEITNLQ-----------NMVRASSSKIQKHVSF 1560
               K+N++   L EN+++  EI   N EI NL+           N  + S S IQ H+  
Sbjct: 3078 LQKKSNKINFILAENEKLQNEIEKNNKEIENLRKKLKSNEEKLNNQQKESKSSIQNHLQI 3137

Query: 1561 ASDTKQGRDEQLDNTMNKELLDAVPRAELDL 1591
             +D K+  +E  +    KE        E DL
Sbjct: 3138 NNDLKKENEELSNQLKLKEDEKQKQNEEFDL 3168



 Score =  181 bits (440), Expect = 2e-43
 Identities = 326/1504 (21%), Positives = 648/1504 (43%), Gaps = 164/1504 (10%)

Query: 144  VTHLSNTIKEKDNALSVLQVKMKIMETTILDLQ-EKINEKDQIIEAKNKATTXXXXXXXX 202
            +T L NT+++KD+ +S L+ K   +E  I DL+ EK  + +++   KNK           
Sbjct: 1283 MTSLQNTLQDKDSEISDLKEKNSQLELKIEDLEGEKSKDNEKM---KNK---------DL 1330

Query: 203  XXXXXXXXXEDTKQQMTKMQ--ENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLL 260
                     E+ K Q+ + Q   N  A+       K+     +++++V + ++   N+ L
Sbjct: 1331 QIKLMESTIENMKSQLNESQSLNNEYALLQSTLQSKENQFSKLQNENVMLQTM---NQNL 1387

Query: 261  EAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIAN 320
                  +   H++  Q+L Q                 Q ++ S  +K +++       +N
Sbjct: 1388 TNENASMKENHNREIQKL-QNDLQNKEFQEKMINSELQKLKESLTQK-DLQISNLSRYSN 1445

Query: 321  MTELTKK---IELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRN 377
              EL  K   IE L + N ++++TN +LE+++     E   ++S  K+    +  +   N
Sbjct: 1446 ENELKNKNIQIEYLTNENKKLKETNLDLESQIRKKDNEINDINSNLKRKENQL--QETEN 1503

Query: 378  TASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXX 437
            T   +++   +  +E  N D + +INK  +  L    Q  N DLV+ +  +  KD     
Sbjct: 1504 TNRNLQNDIKRKQNE--NNDLENEINK--LKDLLSKSQHDN-DLVNND--LKRKDLQNRD 1556

Query: 438  XXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVN 497
                        ++LQL     ME         N    N+I +++  LK+      K++N
Sbjct: 1557 LENKLKNLKDKSSELQLS-LSRME-------SDNKRKDNQIIELENDLKKS-----KEIN 1603

Query: 498  VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEI 557
               L   LK  E QI++L ++    N ++IK K N    L    K++       +S  + 
Sbjct: 1604 -NSLSNDLKRKENQISELQNQ---QNTDLIK-KQNENNDLMNENKSLKELIAKKESEND- 1657

Query: 558  VRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAIS 617
              +  EL   + ++ +LE+E  +L    VD +      +D+  ++  M++L       IS
Sbjct: 1658 -SINSELKRRTLQINDLEKEIKDLASKRVDEN------NDLSNQIKNMKDL-------IS 1703

Query: 618  LLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLE--EQIDALSASK 675
              E++   +  EL  +  + +++++ LA   + + + + +E+K +  E  +  D  S S+
Sbjct: 1704 KKETENNSINNELRRVNSQNNDLKELLAK-KESEINAINNELKRISSENNDLKDINSKSE 1762

Query: 676  KELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISEL 735
                  ++NLK    QL    + L     +  NKL++ I E       L+  + + ++  
Sbjct: 1763 NNYQDQLKNLKNQLTQLKNENQKLMKSSTEEKNKLKDLINEKNIQIQSLQSKNEDLVNN- 1821

Query: 736  LAKINHEEQSKIQTQFGIDAKIQERDLYI---ENIESELSKYKSRICRLEESIAVMEDRR 792
             +KIN++ +S    Q  +D K  +  + I   E +++EL   K+ I  L++      D+ 
Sbjct: 1822 QSKINNKLES---IQKDLDEKENQNSVLISENEKLQNELMSSKTEIQTLDQKETEFNDKL 1878

Query: 793  YSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQ 852
              +ER    L S + + ++  +  T + +E ++     +     +E    + + +  E +
Sbjct: 1879 REMERNNRSLSSQINDLKEKLNNLT-ETNEKISDENTKLKQQMKIESANNQKQLKQLETE 1937

Query: 853  KKNQILLEENQNLQISLSDMQQHYNALVEKANRT--DLAESESTKYQTQLRDLESNLKRI 910
            K N+ L EEN  L+  +S        L +++ +T  DL ES   K +  L  LE +   I
Sbjct: 1938 KLNR-LQEENNKLKSQISKKDSDLQKLKQESEQTINDLKESLLNK-EESLSILEKSADFI 1995

Query: 911  T----------HEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQL 960
            T          +E+  +I Q +++I   +    T +++ I+  +   ++ EK+ + V QL
Sbjct: 1996 TKQIDGKSKSINENSQIIEQMQEKIIQKD-NATTDLQNKIKQLESQLQQNEKDNDKVKQL 2054

Query: 961  EAQLQEYKNNIENLNMNVEELNKMN---LELID-------KHVQKQQTQSPDYTEQYINE 1010
            + +L+E++  I+NL   + +LN  N    +LI+       K +Q    ++   T+ + ++
Sbjct: 2055 QTELKEHQLKIKNLEEKIVKLNNENNSLQKLINSKDDEKVKQLQNNINENEAKTKTFEDQ 2114

Query: 1011 INKL----NALLK---QKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEE 1063
            I KL    N+L K   + D ++ +  ++I N       ++   E+K+ + T   +N   E
Sbjct: 2115 IQKLTSENNSLRKNINENDSKVKSYQEEIQNLTNEKNDLIKSSETKIKELTESSKNQISE 2174

Query: 1064 M-QRVS----KQLLDSKQHNEELQIL----------VREQDDQIKELKETKLTFEMNIPK 1108
            + QR+     K  LD ++   E+QI           + E + ++ E+K      ++ + +
Sbjct: 2175 LNQRLQDVTRKSDLDLQKKEMEIQIANKNISDLHQQLLESNQKLNEIKLQANNQQLQLKQ 2234

Query: 1109 TEGMI--ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNT 1166
             E  +   +S IE + ++  N               ++ +++E IQ    LQEQ + L  
Sbjct: 2235 KENDLTTANSIIETLKNEIEN----TMNKSSILVQNEMNKKDEIIQN---LQEQLSNLKQ 2287

Query: 1167 ELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISS 1226
            E  E  +K+   +   TEL        ++IN LK    Q + +  +L         ++S+
Sbjct: 2288 ETNEEISKLQNDKNNQTELLNLIKSKNDEINNLKEINRQKDQQIMDLKRYEQTELLNLSN 2347

Query: 1227 AVDQ-RGFEI---AELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEE 1282
              DQ R   I   +    + L Q + D Q  E  +  QL +   + ++ + ++Q+   E+
Sbjct: 2348 NDDQNRSSSIVYNSSTLMKSLRQVKEDSQIREKFIDDQLKSLSMQKDEEIKNLQNKNSEK 2407

Query: 1283 TNKIVTME-QVTSL-QNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAF--XXXX 1338
              KI  +E Q+ +L  N    KEE + N  +  +++ +  + +     D    F      
Sbjct: 2408 DEKIRDLEKQINNLSDNSNHIKEESMINEVKLKSNIDSMNDKILQMQNDSNQLFKENQNL 2467

Query: 1339 XXXXXXXXXXXXDLRTENQSYKQ-MQEQSILN--INEENAQLKK-------SSXXXXXXX 1388
                        D   EN+S KQ +Q  + LN  + EEN ++ K       ++       
Sbjct: 2468 RNSIDKLNKQIKDFEQENESLKQTIQSFTKLNNELTEENEKIYKKYNDLINNNAVNENNL 2527

Query: 1389 XXXXXRVNDAEAKVLELTHQLEL---KDSEIYQKTHEYTITLTQRNDEFENVRQQLV--E 1443
                 + N  + K+LELT  LE+    D +   K +E    L ++    + ++ QL    
Sbjct: 2528 QVMKDQNNKNQIKILELTRNLEMSKFNDDQNKDKINELETDLAEKEKLIKLLQNQLTVSS 2587

Query: 1444 YEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNK 1503
             +K ++ +  +K+ E+     K++EN    + +Q  ++IE++K  EE N K  E ++  K
Sbjct: 2588 SDKDMKQILQQKDEEIR----KLNENNGKIKVLQ--NQIEKMK--EENNSKTNELLNQLK 2639

Query: 1504 QVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMV-RASSSKIQKHVSFAS 1562
            +      +LE E  K     + L   +  +  +  ++  + N++ +  S +  K  +  +
Sbjct: 2640 ESENKRISLEAEKKKLEIEISNLNIDDNNLKLMEQKMKEMSNVINKLQSQESDKDRTIMN 2699

Query: 1563 DTKQ 1566
             TKQ
Sbjct: 2700 QTKQ 2703



 Score =  173 bits (421), Expect = 3e-41
 Identities = 265/1303 (20%), Positives = 579/1303 (44%), Gaps = 114/1303 (8%)

Query: 337  QIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSET--- 393
            ++ Q N  L   +  +  E +++ +  K+     +    +    +MK  +  L  E    
Sbjct: 203  ELTQENDNLRENIENLNKEIESLQNKIKENQ---NTPQTQQQYEEMKKKYENLKIENNSQ 259

Query: 394  ---LNQDTDKKIN-KNEIAKL--EMVIQSLNKDLVDKE-YVISEKDTXXXXXXXXXXGKD 446
               ++Q TD+    + EI KL  E++   L  D   K+ Y  S++             KD
Sbjct: 260  KILIDQRTDELTKARQEIGKLQQELMGDDLPNDKAFKDIYKESQEKIVNLQTENNQLKKD 319

Query: 447  TLIAQLQLEH--------QQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNV 498
               A+ + E+          ++   SL++   N + +N++    ++++  +  +  D+  
Sbjct: 320  LENAKTEQENLNQKLNNLNNNLNDNSLLNKSLN-DQINQLKVELQKMQNTIYKKDGDLQE 378

Query: 499  KD-LIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFS----KVSDS 553
            KD  IE+LK         ++E++  NK + ++ + +          + +F+    +++D+
Sbjct: 379  KDDEIEQLKQTLNAQKTFSNELEETNKKLKEMLNQNSKSDLTNSSFLSSFNLTKQRLNDT 438

Query: 554  NKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRL 613
             +E  +L  +L  L Q++  L++E  NL+     Y       S++    I   +  +   
Sbjct: 439  KQENEQLQNQLMQLQQQLLILKQENENLKEKQNSYSDSLNNSSNMSALDISGSDFVQIDQ 498

Query: 614  KAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSA 673
              I   E +   L   +  L++K  + E+     S+  +D   S ++ + L++ +D   A
Sbjct: 499  AIIDQYEQRIKSLTDNISELREKISQKEN-----SEKSNDSQRS-LELIQLKKSLD--KA 550

Query: 674  SKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKIS 733
             K+  ++  EN KL+  QL    K   ++   ++N L    +E   L   L+K    K  
Sbjct: 551  KKENYSIKEENFKLN--QLLNNYKRKIDNLNQLLNDLNP--KEIKLLLSSLKKDFLLKRD 606

Query: 734  ELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRY 793
            + +  I    ++K + +   +A  +  DL IEN+++EL   K +   L+ S A  E+++ 
Sbjct: 607  DFIKYIR---KAKNEVR---NALSENSDL-IENLQNELLNMKEK---LQNSKA--ENKQI 654

Query: 794  -SLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQ 852
             SL+ K + L   + + QK          E  N +  L D +  +     +++ ENKEL+
Sbjct: 655  LSLQPKINDLNKIMTQIQKENERLQKTNKEKNNEIEKLKDENENLVSNNKKLQTENKELK 714

Query: 853  K-------KNQILLEENQNLQISLSDMQQHYNALVE-KANRTDLAESESTKYQTQLRDLE 904
            +       +N  LL EN +L   L++++     L + K  +  L +   +     L D  
Sbjct: 715  ENLEKETSQNSDLLNENSDLNDKLNELRNQIKTLNDDKTKQNQLLQKNLSNQLKDLLDEN 774

Query: 905  SNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRD-KKVLNEKYEKN---IEYVTQL 960
            ++LK    + Q+   Q +K+I+DL      Q ES  ++ +  +NEK  +N    E +  L
Sbjct: 775  NSLKDQLAQLQSSNNQLQKDIKDL----TRQNESKTKELQSKINEKENENQNLTEKLNSL 830

Query: 961  EAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQ 1020
            ++Q+Q  +N  E+L  ++E +           + + Q ++ +  E+   +I K N +L+ 
Sbjct: 831  QSQIQILQNGNEDLQNDIESITNA--------LNQSQNENKELKEEN-QKIEKSNQILQY 881

Query: 1021 KDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEE 1080
            +++E+    +K+ N        + D +++ +    K++ + EE+  ++++        +E
Sbjct: 882  ENKEVKEQKEKLQN-------QIDDLKNQNSNLQNKVDELNEEISSINEE---KSNQEKE 931

Query: 1081 LQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXX 1140
             Q ++++ + ++K L+  +L  E N   TE + + +T     DD+   D           
Sbjct: 932  YQEMLKDLETKLKNLEAERL--ESNKEITEILELDTTF----DDSTISDHLRKQCEQLKS 985

Query: 1141 XLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLK 1200
             ++  + +   +E   L+ Q+  L  + +E   +++  +T   +L        ++I+ LK
Sbjct: 986  LIEQNKNQN--EEIQNLKSQNEDLTVKNEEMKKELMNNQTTICDLIKTSEDKDKEIDDLK 1043

Query: 1201 SKLEQLNTENDN----LLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHE 1256
             K+E+L +E DN    L +T+ E + S    + Q         K+ L Q+  + QK   E
Sbjct: 1044 QKIEKLKSEIDNSKKQLDTTLTEFKVSNFDEL-QSQISRNNDDKKKLEQKVQNLQKENEE 1102

Query: 1257 LRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQ-NKLQDKEEHLRNLQEKYAD 1315
            ++++L   E++ + L  S++S       K+   +++  +Q  +LQ + + L   + K + 
Sbjct: 1103 MKIKLENKENERKSL-SSLESENILLKQKLQNNDKLHQIQIGELQKEIDVLNQTKSKLSK 1161

Query: 1316 VINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENA 1375
             ++ I      ++++                     L  EN SY+    QS+   +  + 
Sbjct: 1162 EVDDITNENITLKNQINTTFSMSIDENNELKKKLNQLIKENNSYQLQLNQSVPKEDFIDL 1221

Query: 1376 QLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLE-LKDS-EIYQKT-HEYTITLTQRND 1432
            Q K S               N+++A + +    ++ LK S ++ QK       T+  +N 
Sbjct: 1222 QNKISDLENELQNSVSLKDYNESQAYLEKTMSTVDNLKSSVKVAQKELQNMKQTMNNQNT 1281

Query: 1433 EFENVRQQLVEYEKRIEDLTYEKES--ELAILRLKMHENANHYETMQKESEIERVK-LIE 1489
            +  +++  L + +  I DL  EK S  EL I  L+  ++ ++ +   K+ +I+ ++  IE
Sbjct: 1282 KMTSLQNTLQDKDSEISDLK-EKNSQLELKIEDLEGEKSKDNEKMKNKDLQIKLMESTIE 1340

Query: 1490 ELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRA 1549
             +  ++ ES SLN + A L   L+   +K N+  + L+N+ + + T+N  +TN    ++ 
Sbjct: 1341 NMKSQLNESQSLNNEYALLQSTLQ---SKENQF-SKLQNENVMLQTMNQNLTNENASMKE 1396

Query: 1550 SSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDLA 1592
            + ++  + +      K+ +++ +++ + K L +++ + +L ++
Sbjct: 1397 NHNREIQKLQNDLQNKEFQEKMINSELQK-LKESLTQKDLQIS 1438



 Score =  173 bits (420), Expect = 4e-41
 Identities = 321/1619 (19%), Positives = 694/1619 (42%), Gaps = 152/1619 (9%)

Query: 57   AQKCLENAAL-VSKRIKE--HRKATAELLGRPFVPGIS---ESLANTLKQKEILMEKIKQ 110
            AQK   N     +K++KE  ++ + ++L    F+   +   + L +T ++ E L  ++ Q
Sbjct: 392  AQKTFSNELEETNKKLKEMLNQNSKSDLTNSSFLSSFNLTKQRLNDTKQENEQLQNQLMQ 451

Query: 111  YKE---LSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNALSVLQVKMKI 167
             ++   + K+ +  +                    D++  S+ ++     +   + ++K 
Sbjct: 452  LQQQLLILKQENENLKEKQNSYSDSLNNSSNMSALDISG-SDFVQIDQAIIDQYEQRIKS 510

Query: 168  METTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIA 227
            +   I +L+EKI++K+   ++ +   +                    K++  K+ +    
Sbjct: 511  LTDNISELREKISQKENSEKSNDSQRSLELIQLKKSLDKAKKENYSIKEENFKLNQLLNN 570

Query: 228  MEAEWKDEKQRLLKDIESKDVRI--SSLEEANKLLEAARFEISLEHSKLAQELEQXXXXX 285
             + +  D   +LL D+  K++++  SSL++ + LL+   F   +  +K   E+       
Sbjct: 571  YKRKI-DNLNQLLNDLNPKEIKLLLSSLKK-DFLLKRDDFIKYIRKAK--NEVRNALSEN 626

Query: 286  XXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKEL 345
                           E     K E ++  SL+   + +L K +  ++  N ++++TNKE 
Sbjct: 627  SDLIENLQNELLNMKEKLQNSKAENKQILSLQ-PKINDLNKIMTQIQKENERLQKTNKEK 685

Query: 346  ENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKN 405
             N++  +  E++ + S +KK      +   +     ++   SQ +S+ LN+++D     N
Sbjct: 686  NNEIEKLKDENENLVSNNKK-----LQTENKELKENLEKETSQ-NSDLLNENSDLNDKLN 739

Query: 406  EIAKLEMVIQSLNKDLVDKEYVISE--KDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGP 463
            E   L   I++LN D   +  ++ +   +            KD L AQLQ  + Q     
Sbjct: 740  E---LRNQIKTLNDDKTKQNQLLQKNLSNQLKDLLDENNSLKDQL-AQLQSSNNQLQ--- 792

Query: 464  SLIHVGTNTEDVNEIAKVQEQLKQELNDEI--KDVNVKDLIEKLKSAEEQITQL-NDEID 520
                     +D+ ++ +  E   +EL  +I  K+   ++L EKL S + QI  L N   D
Sbjct: 793  ---------KDIKDLTRQNESKTKELQSKINEKENENQNLTEKLNSLQSQIQILQNGNED 843

Query: 521  AAN-----KNMIKVKSNHKLKLKQMQKTIDNFSKVSD-SNKEIVRLTEELHHLSQKVAEL 574
              N      N +    N   +LK+  + I+  +++    NKE+    E+   L  ++ +L
Sbjct: 844  LQNDIESITNALNQSQNENKELKEENQKIEKSNQILQYENKEV---KEQKEKLQNQIDDL 900

Query: 575  EEEKGNLQLHL----VDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQEL 630
            + +  NLQ  +     +  S    +S+  K+  EM    ET+LK +     +    + E+
Sbjct: 901  KNQNSNLQNKVDELNEEISSINEEKSNQEKEYQEMLKDLETKLKNLEAERLESNKEITEI 960

Query: 631  HILQQKYDEVEDKLADISQLQSDQVCSEI-KSVHLEEQIDALSASKKELALVIENLKLDK 689
              L   +D  +  ++D  + Q +Q+ S I ++ +  E+I  L +  ++L +  E +K + 
Sbjct: 961  LELDTTFD--DSTISDHLRKQCEQLKSLIEQNKNQNEEIQNLKSQNEDLTVKNEEMKKEL 1018

Query: 690  EQLYGTIKDL-----ENDKE--DIMNKLQNYIQE----NMDLTDKLEKMSAEKISELLAK 738
                 TI DL     + DKE  D+  K++    E       L   L +       EL ++
Sbjct: 1019 MNNQTTICDLIKTSEDKDKEIDDLKQKIEKLKSEIDNSKKQLDTTLTEFKVSNFDELQSQ 1078

Query: 739  I--NHEEQSKIQTQF-GIDAKIQERDLYIENIESE---LSKYKSRICRLEESI----AVM 788
            I  N++++ K++ +   +  + +E  + +EN E+E   LS  +S    L++ +     + 
Sbjct: 1079 ISRNNDDKKKLEQKVQNLQKENEEMKIKLENKENERKSLSSLESENILLKQKLQNNDKLH 1138

Query: 789  EDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRL----AVLMDHDRVVEKQLLEI 844
            + +   L+++ D L     +  K   + T +   L N++    ++ +D +  ++K+L ++
Sbjct: 1139 QIQIGELQKEIDVLNQTKSKLSKEVDDITNENITLKNQINTTFSMSIDENNELKKKLNQL 1198

Query: 845  EHENK--ELQKKNQILLEENQNLQISLSDMQ---------QHYN---ALVEKANRT-DLA 889
              EN   +LQ    +  E+  +LQ  +SD++         + YN   A +EK   T D  
Sbjct: 1199 IKENNSYQLQLNQSVPKEDFIDLQNKISDLENELQNSVSLKDYNESQAYLEKTMSTVDNL 1258

Query: 890  ESESTKYQTQLRDLESNLKRITHEH---QTLIVQKKKEIEDLEIEFNTQIESAIRDKKVL 946
            +S     Q +L++++  +     +    Q  +  K  EI DL+ E N+Q+E  I D   L
Sbjct: 1259 KSSVKVAQKELQNMKQTMNNQNTKMTSLQNTLQDKDSEISDLK-EKNSQLELKIED---L 1314

Query: 947  NEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLE-------LIDKHVQKQQTQ 999
              +  K+ E +   + Q++  ++ IEN+   + E   +N E       L  K  Q  + Q
Sbjct: 1315 EGEKSKDNEKMKNKDLQIKLMESTIENMKSQLNESQSLNNEYALLQSTLQSKENQFSKLQ 1374

Query: 1000 SPDYTEQYINE-INKLNALLKQK-DEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKL 1057
            + +   Q +N+ +   NA +K+  + EI  L   + N +     M++    KL +  T+ 
Sbjct: 1375 NENVMLQTMNQNLTNENASMKENHNREIQKLQNDLQNKEFQ-EKMINSELQKLKESLTQK 1433

Query: 1058 ENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMI--IS 1115
            +     + R S +  + K  N +++ L  E     K+LKET L  E  I K +  I  I+
Sbjct: 1434 DLQISNLSRYSNE-NELKNKNIQIEYLTNEN----KKLKETNLDLESQIRKKDNEINDIN 1488

Query: 1116 STIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKI 1175
            S ++   +     +             K  E  +   E + L++  +K   +       +
Sbjct: 1489 SNLKRKENQLQETENTNRNLQNDIKR-KQNENNDLENEINKLKDLLSKSQHDNDLVNNDL 1547

Query: 1176 IQLETLNTELTGHDVVNQEQINQLKSKLEQLNTEN----------DNLLSTVAELRSSIS 1225
             + +  N +L       +++ ++L+  L ++ ++N          +N L    E+ +S+S
Sbjct: 1548 KRKDLQNRDLENKLKNLKDKSSELQLSLSRMESDNKRKDNQIIELENDLKKSKEINNSLS 1607

Query: 1226 SAVDQRGFEIAELWKQH---LAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEE 1282
            + + ++  +I+EL  Q    L +++ +     +E +  L    +K E   DS+ S  +  
Sbjct: 1608 NDLKRKENQISELQNQQNTDLIKKQNENNDLMNENK-SLKELIAKKESENDSINSELKRR 1666

Query: 1283 TNKIVTME-QVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXX 1341
            T +I  +E ++  L +K  D+   L N  +   D+I++ E   + I +E           
Sbjct: 1667 TLQINDLEKEIKDLASKRVDENNDLSNQIKNMKDLISKKETENNSINNELRRVNSQNNDL 1726

Query: 1342 XXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAK 1401
                     ++   N   K++  ++  ++ + N++ + +             ++ +   K
Sbjct: 1727 KELLAKKESEINAINNELKRISSEN-NDLKDINSKSENNYQDQLKNLKNQLTQLKNENQK 1785

Query: 1402 VLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAI 1461
            +++ + + + K  ++  + +    +L  +N++  N + ++    + I+    EKE++ ++
Sbjct: 1786 LMKSSTEEKNKLKDLINEKNIQIQSLQSKNEDLVNNQSKINNKLESIQKDLDEKENQNSV 1845

Query: 1462 LRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNE 1521
            L   + EN    E +Q E    + + I+ L+ K TE     +++   N++L  ++   N+
Sbjct: 1846 L---ISEN----EKLQNELMSSKTE-IQTLDQKETEFNDKLREMERNNRSLSSQI---ND 1894

Query: 1522 MQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKEL 1580
            ++  L N       ++DE T L+  ++  S+  QK +      K  R ++ +N +  ++
Sbjct: 1895 LKEKLNNLTETNEKISDENTKLKQQMKIESANNQKQLKQLETEKLNRLQEENNKLKSQI 1953



 Score =  172 bits (419), Expect = 6e-41
 Identities = 298/1465 (20%), Positives = 632/1465 (43%), Gaps = 139/1465 (9%)

Query: 147  LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINE-KDQIIEAKNKATTXXXXXXXXXXX 205
            L N  K     +  LQ ++ ++  T   L +++++  ++ I  KN+  T           
Sbjct: 1131 LQNNDKLHQIQIGELQKEIDVLNQTKSKLSKEVDDITNENITLKNQINTTFSMSIDENNE 1190

Query: 206  XXXXXXEDTKQQMT-KMQENFIAMEAEWKDEKQRLLKDIESK---DVRISSLEEANKLLE 261
                  +  K+  + ++Q N    + ++ D  Q  + D+E++    V +    E+   LE
Sbjct: 1191 LKKKLNQLIKENNSYQLQLNQSVPKEDFID-LQNKISDLENELQNSVSLKDYNESQAYLE 1249

Query: 262  AARFEI-SLEHS-KLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGS---L 316
                 + +L+ S K+AQ+  Q                + +++    E ++++EK S   L
Sbjct: 1250 KTMSTVDNLKSSVKVAQKELQNMKQTMNNQNTKMTSLQNTLQDKDSEISDLKEKNSQLEL 1309

Query: 317  EIANMT-ELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSG 375
            +I ++  E +K  E +++ + QI+     +EN  + +       +  +   S L S++  
Sbjct: 1310 KIEDLEGEKSKDNEKMKNKDLQIKLMESTIENMKSQLNESQSLNNEYALLQSTLQSKE-- 1367

Query: 376  RNTASKMKSPWSQLSSETLNQD-TDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTX 434
             N  SK+++    +  +T+NQ+ T++  +  E    E  IQ L  DL +KE+     ++ 
Sbjct: 1368 -NQFSKLQN--ENVMLQTMNQNLTNENASMKENHNRE--IQKLQNDLQNKEFQEKMINSE 1422

Query: 435  XXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIK 494
                      KD  I+ L     ++      I +   T +  ++ +    L+ ++    K
Sbjct: 1423 LQKLKESLTQKDLQISNLSRYSNENELKNKNIQIEYLTNENKKLKETNLDLESQIRK--K 1480

Query: 495  DVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLK-QMQKTIDNFSKVSDS 553
            D  + D+   LK  E Q+ Q  +  +   +N IK K N    L+ ++ K  D  SK    
Sbjct: 1481 DNEINDINSNLKRKENQL-QETENTNRNLQNDIKRKQNENNDLENEINKLKDLLSKSQHD 1539

Query: 554  N----KEIVRLTEELHHLSQKVAELEEEKGNLQLHL--VDYDSGRM------IESDVYKK 601
            N     ++ R   +   L  K+  L+++   LQL L  ++ D+ R       +E+D+ KK
Sbjct: 1540 NDLVNNDLKRKDLQNRDLENKLKNLKDKSSELQLSLSRMESDNKRKDNQIIELENDL-KK 1598

Query: 602  MIEMENLAETRLKA----ISLLESQK-FDLVQ---ELHILQQKYDEVEDKLADISQLQSD 653
              E+ N     LK     IS L++Q+  DL++   E + L  +   +++ +A   + ++D
Sbjct: 1599 SKEINNSLSNDLKRKENQISELQNQQNTDLIKKQNENNDLMNENKSLKELIAK-KESEND 1657

Query: 654  QVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNY 713
             + SE+K   L  QI+ L    K+LA    +   D       +KDL + KE   N + N 
Sbjct: 1658 SINSELKRRTL--QINDLEKEIKDLASKRVDENNDLSNQIKNMKDLISKKETENNSINNE 1715

Query: 714  IQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSK 773
            ++      + L+++ A+K SE+ A IN+E + +I ++          DL   N +SE + 
Sbjct: 1716 LRRVNSQNNDLKELLAKKESEINA-INNELK-RISSE--------NNDLKDINSKSE-NN 1764

Query: 774  YKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDH 833
            Y+ ++  L+  +  +++    L + + +  + L++     +E  IQ   L ++   L+++
Sbjct: 1765 YQDQLKNLKNQLTQLKNENQKLMKSSTEEKNKLKD---LINEKNIQIQSLQSKNEDLVNN 1821

Query: 834  DRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESES 893
               +  +L  I+ +  E + +N +L+ EN+ LQ          N L+         + + 
Sbjct: 1822 QSKINNKLESIQKDLDEKENQNSVLISENEKLQ----------NELMSSKTEIQTLDQKE 1871

Query: 894  TKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLE--IEFNTQIESAIRDKKVLNEKYE 951
            T++  +LR++E N + ++ +   L  +     E  E   + NT+++  ++ +   N+K  
Sbjct: 1872 TEFNDKLREMERNNRSLSSQINDLKEKLNNLTETNEKISDENTKLKQQMKIESANNQKQL 1931

Query: 952  KNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEI 1011
            K +E  T+   +LQE  N +++      +++K + +L     + +QT + D  E  +N+ 
Sbjct: 1932 KQLE--TEKLNRLQEENNKLKS------QISKKDSDLQKLKQESEQTIN-DLKESLLNKE 1982

Query: 1012 NKLNALLKQKD---EEIIALNQKIN-NAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRV 1067
              L+ L K  D   ++I   ++ IN N+Q+     +   + K+ Q     +N   ++Q  
Sbjct: 1983 ESLSILEKSADFITKQIDGKSKSINENSQI-----IEQMQEKIIQ----KDNATTDLQNK 2033

Query: 1068 SKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANN 1127
             KQL    Q NE+        +D++K+L+      ++ I   E  I+      ++++ N+
Sbjct: 2034 IKQLESQLQQNEK-------DNDKVKQLQTELKEHQLKIKNLEEKIVK-----LNNENNS 2081

Query: 1128 VDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTG 1187
            +             +  +++E+  Q ++ + E  AK  T   +    I +L + N  L  
Sbjct: 2082 LQKL----------INSKDDEKVKQLQNNINENEAKTKTFEDQ----IQKLTSENNSLRK 2127

Query: 1188 HDVVNQEQINQLKSKLEQL-NTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQR 1246
            +   N  ++   + +++ L N +ND + S+  +++    S+ +Q   E+ +  +    + 
Sbjct: 2128 NINENDSKVKSYQEEIQNLTNEKNDLIKSSETKIKELTESSKNQIS-ELNQRLQDVTRKS 2186

Query: 1247 EADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHL 1306
            + D QK E E+++        ++QLL+S Q   + +        Q+   +N L      +
Sbjct: 2187 DLDLQKKEMEIQIANKNISDLHQQLLESNQKLNEIKLQANNQQLQLKQKENDLTTANSII 2246

Query: 1307 RNLQEKYADVINQIEIL-------RSEI---EDEKVAFXXXXXXXXXXXXXXXXDLRTEN 1356
              L+ +  + +N+  IL       + EI     E+++                 + +TE 
Sbjct: 2247 ETLKNEIENTMNKSSILVQNEMNKKDEIIQNLQEQLSNLKQETNEEISKLQNDKNNQTEL 2306

Query: 1357 QSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRV--NDAEAKVLELTHQLELKDS 1414
             +  + +   I N+ E N Q  +               +  ND + +   + +       
Sbjct: 2307 LNLIKSKNDEINNLKEINRQKDQQIMDLKRYEQTELLNLSNNDDQNRSSSIVYNSSTLMK 2366

Query: 1415 EIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYE 1474
             + Q   +  I     +D+ +++  Q  E  K +++   EK+ ++  L  +++  +++  
Sbjct: 2367 SLRQVKEDSQIREKFIDDQLKSLSMQKDEEIKNLQNKNSEKDEKIRDLEKQINNLSDNSN 2426

Query: 1475 TMQKESEIERVKL---IEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEI 1531
             +++ES I  VKL   I+ +N KI +  + + Q+ + N+ L   + K N+     E +  
Sbjct: 2427 HIKEESMINEVKLKSNIDSMNDKILQMQNDSNQLFKENQNLRNSIDKLNKQIKDFEQENE 2486

Query: 1532 EIVTLNDEITNLQNMVRASSSKIQK 1556
             +       T L N +   + KI K
Sbjct: 2487 SLKQTIQSFTKLNNELTEENEKIYK 2511



 Score =  169 bits (412), Expect = 4e-40
 Identities = 318/1546 (20%), Positives = 663/1546 (42%), Gaps = 176/1546 (11%)

Query: 168  METTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIA 227
            +E+   DL EK N+   +I    K                    E    ++ +M+ N  +
Sbjct: 1829 LESIQKDLDEKENQNSVLISENEKLQNELMSSKTEIQTLDQKETE-FNDKLREMERNNRS 1887

Query: 228  MEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXX 287
            + ++  D K++L    E+ + +IS  +E  KL +    ++ +E +   ++L+Q       
Sbjct: 1888 LSSQINDLKEKLNNLTETNE-KIS--DENTKLKQ----QMKIESANNQKQLKQLETEKLN 1940

Query: 288  XXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTE-LTKKIELLEHLNCQIRQTNKELE 346
                     K  I     +  +++++    I ++ E L  K E L  L        K+++
Sbjct: 1941 RLQEENNKLKSQISKKDSDLQKLKQESEQTINDLKESLLNKEESLSILEKSADFITKQID 2000

Query: 347  NKLATMGTESKAVSSPSKKGSPLISRKSGRNT--ASKMKSPWSQLSSETLNQD------T 398
             K  ++   S+ +    +K    I +K    T   +K+K   SQL     + D      T
Sbjct: 2001 GKSKSINENSQIIEQMQEK----IIQKDNATTDLQNKIKQLESQLQQNEKDNDKVKQLQT 2056

Query: 399  DKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQ 458
            + K ++ +I  LE  I  LN +    + +I+ KD            ++    +   +  Q
Sbjct: 2057 ELKEHQLKIKNLEEKIVKLNNENNSLQKLINSKDDEKVKQLQNNINENEAKTKTFEDQIQ 2116

Query: 459  HM--EGPSLI-HVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQL 515
             +  E  SL  ++  N   V    +  + L  E ND IK    K + E  +S++ QI++L
Sbjct: 2117 KLTSENNSLRKNINENDSKVKSYQEEIQNLTNEKNDLIKSSETK-IKELTESSKNQISEL 2175

Query: 516  NDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHL----SQKV 571
            N  +    +     KS+  L+ K+M+  I N   +SD +++++   ++L+ +    + + 
Sbjct: 2176 NQRLQDVTR-----KSDLDLQKKEMEIQIAN-KNISDLHQQLLESNQKLNEIKLQANNQQ 2229

Query: 572  AELEEEKGNL------------QLHLVDYDSGRMIESDVYKKMIEMENLAE--TRLKA-- 615
             +L++++ +L            ++      S  ++++++ KK   ++NL E  + LK   
Sbjct: 2230 LQLKQKENDLTTANSIIETLKNEIENTMNKSSILVQNEMNKKDEIIQNLQEQLSNLKQET 2289

Query: 616  ---ISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDAL- 671
               IS L++ K +  + L++++ K DE+ + L +I++ Q DQ   ++K     E ++   
Sbjct: 2290 NEEISKLQNDKNNQTELLNLIKSKNDEINN-LKEINR-QKDQQIMDLKRYEQTELLNLSN 2347

Query: 672  --------------SASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQEN 717
                          S   K L  V E+ ++ ++ +   +K L   K++ +  LQN   E 
Sbjct: 2348 NDDQNRSSSIVYNSSTLMKSLRQVKEDSQIREKFIDDQLKSLSMQKDEEIKNLQNKNSEK 2407

Query: 718  MDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSR 777
             +    LEK    +I+ L    NH ++  +  +  + + I   +  I  ++++ ++    
Sbjct: 2408 DEKIRDLEK----QINNLSDNSNHIKEESMINEVKLKSNIDSMNDKILQMQNDSNQLFKE 2463

Query: 778  ICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVV 837
               L  SI  +  +    E++ + L   +Q   K  +E T + +++  +   L++++ V 
Sbjct: 2464 NQNLRNSIDKLNKQIKDFEQENESLKQTIQSFTKLNNELTEENEKIYKKYNDLINNNAVN 2523

Query: 838  EKQLLEIEHENKELQKKNQI-LLEENQNLQISLSDMQQHYNALVEKANRTDLAESEST-- 894
            E  L  ++ +N     KNQI +LE  +NL++S  +  Q+ + + E    TDLAE E    
Sbjct: 2524 ENNLQVMKDQNN----KNQIKILELTRNLEMSKFNDDQNKDKINEL--ETDLAEKEKLIK 2577

Query: 895  --KYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNT----QIESAIRDKKVLNE 948
              + Q  +   + ++K+I  +    I +  +    +++  N     + E+  +  ++LN+
Sbjct: 2578 LLQNQLTVSSSDKDMKQILQQKDEEIRKLNENNGKIKVLQNQIEKMKEENNSKTNELLNQ 2637

Query: 949  KYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLEL--IDKHVQKQQTQSPDYTEQ 1006
              E   + ++ LEA+ ++ +  I NLN++   L  M  ++  +   + K Q+Q  D    
Sbjct: 2638 LKESENKRIS-LEAEKKKLEIEISNLNIDDNNLKLMEQKMKEMSNVINKLQSQESDKDRT 2696

Query: 1007 YINE---INKL-------------NALLKQKDEEIIALNQKINNAQVS----YMSMVSDY 1046
             +N+   I KL             N LL+ +  ++ +   +I++A ++     MS +S  
Sbjct: 2697 IMNQTKQIKKLGSIMTKAKSLKAENTLLRSQISDLESSKTEISSASLNSSSPQMSSLSQK 2756

Query: 1047 E--SKLAQFTTKL--ENMEEEMQRVSKQLLDSKQ---HNEELQILVREQDDQIKELKETK 1099
            +  S+L +  T+L  EN + +M+ + K   D       NE+LQ+ ++  + Q+ ++KE +
Sbjct: 2757 KKISRLEKQVTELLQENEDLKMEIIHKSTSDENLDSLENEKLQLRIKSLETQLNKMKEIE 2816

Query: 1100 LTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLK-VQEEEEFIQERSVLQ 1158
                 N+ KT+   +    + +S +  ++             LK ++E  E +++ S  +
Sbjct: 2817 -NENKNL-KTKVSFMEENSKKLSSEIESLIKKNGEMKINLVSLKSIKENFEILEKSSKER 2874

Query: 1159 EQS-----AKLNTELQECYTKIIQLETLNTELTGHDVVN----QEQINQLKSKLEQLNTE 1209
            E       A    ++ +  TK+  LE   ++L   + +N    Q+  N LK K  QL   
Sbjct: 2875 EAEYSKYRASQEKKVNDLQTKLSTLENDYSDLKNENEMNVLEIQKITNNLKLKENQLQRS 2934

Query: 1210 NDN---------LLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQ 1260
             DN          L+T       +S+ +  R  EI +L K  + +   D ++    + V 
Sbjct: 2935 LDNDKTMDSLQATLNTKTSENQKLSTELVLRNNEIKDL-KDEIGKVNNDKEELMKIINVN 2993

Query: 1261 LSAFESKYEQLLD---SVQSSTQE-ETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADV 1316
             +  +   + LLD    ++   +E + NK    +++     K+ +    ++ ++E    +
Sbjct: 2994 NTLVQKLQKDLLDRNNQIEFLNKEIQENKEEFDQKINESNTKIDELNNIIKQMKETIKSL 3053

Query: 1317 INQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQ 1376
             N  + L+S IE  +                    L  EN+  +   E++   I     +
Sbjct: 3054 SNDKDNLKSTIEGNEDEIHRIANKLQKKSNKINFIL-AENEKLQNEIEKNNKEIENLRKK 3112

Query: 1377 LKKSSXXXXXXXXXXXXRV-------NDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQ 1429
            LK +              +       ND + +  EL++QL+LK+ E  ++  E+ + + Q
Sbjct: 3113 LKSNEEKLNNQQKESKSSIQNHLQINNDLKKENEELSNQLKLKEDEKQKQNEEFDLKIKQ 3172

Query: 1430 RNDEFENVRQQLVEYEKRIED----LTYEKE---SELAILRLKMHENANHYETMQKE--- 1479
            + +E   ++ ++   + + E+    +  EKE    E   L  K+ E   + E + K+   
Sbjct: 3173 KEEEISKLKDEISNLQNKKEEANQNIINEKEELIKENGDLHHKIDELQTNIEDLNKKLIS 3232

Query: 1480 SEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQ---TALENQ--EIEIV 1534
            S+ E  K+I +L   + ES+   K  A+L    + ++ K NE +     LEN+  + +I 
Sbjct: 3233 SQRENEKIINKLKKDLEESIKSQKVQAKLINHRDNKL-KENEKEVHSVLLENEILKSDIK 3291

Query: 1535 TLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKEL 1580
              ++EI  L      S+S     ++ A+D+    D Q +N + K++
Sbjct: 3292 KKSNEIDRLNKQYLTSTS-----ITLANDSNL-FDRQANNDLQKQI 3331



 Score =  164 bits (399), Expect = 2e-38
 Identities = 278/1437 (19%), Positives = 609/1437 (42%), Gaps = 113/1437 (7%)

Query: 164  KMKIMETTILDLQEKINE---KDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTK 220
            ++KI+E T      K N+   KD+I E +                      +   +Q+ +
Sbjct: 2538 QIKILELTRNLEMSKFNDDQNKDKINELETDLAEKEKLIKLLQNQLTVSSSDKDMKQILQ 2597

Query: 221  MQENFIAMEAEWKDEKQRLLKDIES-KDVRISSLEEA-NKLLEAARFEISLEHSKLAQEL 278
             ++  I    E   + + L   IE  K+   S   E  N+L E+    ISLE  K   E+
Sbjct: 2598 QKDEEIRKLNENNGKIKVLQNQIEKMKEENNSKTNELLNQLKESENKRISLEAEKKKLEI 2657

Query: 279  EQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQI 338
            E                  + +     +    E      I N T+  KK+  +      +
Sbjct: 2658 EISNLNIDDNNLKLMEQKMKEMSNVINKLQSQESDKDRTIMNQTKQIKKLGSIMTKAKSL 2717

Query: 339  RQTNKELENKLATMGTESKAVSSPS-KKGSPLISRKSGRNTASKMKSPWSQLSSET---- 393
            +  N  L ++++ + +    +SS S    SP +S  S +   S+++   ++L  E     
Sbjct: 2718 KAENTLLRSQISDLESSKTEISSASLNSSSPQMSSLSQKKKISRLEKQVTELLQENEDLK 2777

Query: 394  ---LNQDT-DKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLI 449
               +++ T D+ ++  E  KL++ I+SL   L   + + +E                 L 
Sbjct: 2778 MEIIHKSTSDENLDSLENEKLQLRIKSLETQLNKMKEIENENKNLKTKVSFMEENSKKLS 2837

Query: 450  AQLQLEHQQHMEGP-SLIHVGTNTEDVNEIAKVQEQLKQELND--EIKDVNVKDLIEKLK 506
            ++++   +++ E   +L+ + +  E+   + K  ++ + E +     ++  V DL  KL 
Sbjct: 2838 SEIESLIKKNGEMKINLVSLKSIKENFEILEKSSKEREAEYSKYRASQEKKVNDLQTKLS 2897

Query: 507  SAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHH 566
            + E   + L +E +     + K+ +N KLK  Q+Q+++DN   +      +   T E   
Sbjct: 2898 TLENDYSDLKNENEMNVLEIQKITNNLKLKENQLQRSLDNDKTMDSLQATLNTKTSENQK 2957

Query: 567  LSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDL 626
            LS ++     E  +L+  +   ++    + +   K+I + N    +L+   L  + + + 
Sbjct: 2958 LSTELVLRNNEIKDLKDEIGKVNN----DKEELMKIINVNNTLVQKLQKDLLDRNNQIEF 3013

Query: 627  VQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLK 686
            + +   +Q+  +E + K+ + S  + D++ + IK   ++E I +LS  K  L   IE  +
Sbjct: 3014 LNKE--IQENKEEFDQKINE-SNTKIDELNNIIKQ--MKETIKSLSNDKDNLKSTIEGNE 3068

Query: 687  LDKEQLYGTIKDLENDKEDIM---NKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEE 743
             +  ++   ++   N    I+    KLQN I++N    + L K   +   E L     E 
Sbjct: 3069 DEIHRIANKLQKKSNKINFILAENEKLQNEIEKNNKEIENLRK-KLKSNEEKLNNQQKES 3127

Query: 744  QSKIQTQFGIDAKIQERDLYIENIESELS-KYKSRICRLEESIAVMEDRRYSLERKADQL 802
            +S IQ    I+  +++ +   E + ++L  K   +  + EE    ++ +   + +  D++
Sbjct: 3128 KSSIQNHLQINNDLKKEN---EELSNQLKLKEDEKQKQNEEFDLKIKQKEEEISKLKDEI 3184

Query: 803  GSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKEL---QKKNQILL 859
             +   +K++A      +++EL+     L  H ++ E Q   IE  NK+L   Q++N+ ++
Sbjct: 3185 SNLQNKKEEANQNIINEKEELIKENGDL--HHKIDELQT-NIEDLNKKLISSQRENEKII 3241

Query: 860  EE-NQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLI 918
             +  ++L+ S+   +     +  + N+    E E      +   L+S++K+         
Sbjct: 3242 NKLKKDLEESIKSQKVQAKLINHRDNKLKENEKEVHSVLLENEILKSDIKK--------- 3292

Query: 919  VQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNV 978
              K  EI+ L  ++ T     + +   L ++   N +   Q+E+   + +   +NL    
Sbjct: 3293 --KSNEIDRLNKQYLTSTSITLANDSNLFDRQANN-DLQKQIESLQNQNQMLTQNLTRMR 3349

Query: 979  EELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDE------EIIALNQKI 1032
            EE+++ N E+I+   ++ +TQ  D ++   N +NK   +L+ K+E      EI     ++
Sbjct: 3350 EEIDQRNTEIIEIKRERTETQINDNSQLKENLLNKEKEILRLKNENQELIKEITDKTLRL 3409

Query: 1033 NNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQI 1092
            +  + +++      +        KL  +E E + + ++L  ++  NE++   ++ +DD+I
Sbjct: 3410 SEVEKNFLKQTISSKDYEMSMKPKLLELEAENKSLKEELNANEVDNEKI---LKLKDDEI 3466

Query: 1093 KELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQ 1152
              L++ K    + I   E     +  + + +    +             L    +E    
Sbjct: 3467 NNLQKAKGDLNLKIVAMENSQKINEKKKVKEIILKLQKMEVENKDLTNRLNDLMKENEDL 3526

Query: 1153 ERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKS---KLEQLNTE 1209
            +R++      K  TE  E   K+ +++  N  ++    + ++++N+ +S   KL +   E
Sbjct: 3527 KRNISDLMKGKSLTE--ELNKKLDEIKRSNIAISTELEITKQKLNKEESSKRKLMKKIEE 3584

Query: 1210 NDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYE 1269
              +L+  + E   S+  + + +  +I E     + + E   QK E +L  + +  E K  
Sbjct: 3585 QKSLIKKLNEENDSLKKSEEDKIGKIKENENNLILETEKSKQK-EEDLLKKNNDLEKKLL 3643

Query: 1270 QLLDSVQSSTQEETNKIVTME-QVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIE 1328
            +   ++    ++  ++I  ++ ++  L    +D+ + + NL +  + + N I  L  +I+
Sbjct: 3644 EYQKNIAELNEKHKHEIDLLQSKINDLTKFKEDQTKEITNLNQIISQLKNDILKLNQQID 3703

Query: 1329 DEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXX 1388
            D    F                DL+ +    K   E   L    E  +L +         
Sbjct: 3704 DLNQKFNEKQKECEQIET----DLKQKEVKNKSQTE---LQFEAEKKKLVE--------- 3747

Query: 1389 XXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRI 1448
                 +++    +++ LT+  + K  E  QK  +    L + N+E+++ R    +YE +I
Sbjct: 3748 -----QISSLNNEIMSLTND-KAKLEEDQQKLIK---KLKKLNEEYQSKRS---DYEFQI 3795

Query: 1449 EDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAEL 1508
            + +T   E E+  L++ + +  N  E ++ E+  E++  I +   K  E   L K +++L
Sbjct: 3796 KTITNNYEDEIQKLKVTIKKLENELELLKIEN--EKINGILQAREKTNE--KLRKSISDL 3851

Query: 1509 NKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSS----KIQKHVSFA 1561
              +  ++ +K NEM       ++ I  L  E+ +L+N  + +SS    K++K+   A
Sbjct: 3852 RDSSNDD-SKYNEM-------KLTIAKLKSELNSLRNQSKENSSISDDKLEKYKQIA 3900



 Score =  160 bits (388), Expect = 3e-37
 Identities = 285/1490 (19%), Positives = 638/1490 (42%), Gaps = 118/1490 (7%)

Query: 145  THLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXX 204
            T L N IK K++ ++ L+   +  +  I+DL  K  E+ +++   N              
Sbjct: 2304 TELLNLIKSKNDEINNLKEINRQKDQQIMDL--KRYEQTELLNLSNNDDQNRSSSIVYNS 2361

Query: 205  XXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAAR 264
                      K+  ++++E FI  + +       + KD E K+++  + E+  K+ +  +
Sbjct: 2362 STLMKSLRQVKED-SQIREKFIDDQLK----SLSMQKDEEIKNLQNKNSEKDEKIRDLEK 2416

Query: 265  FEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTEL 324
             +I+          E+              +  + ++   +     +E  +L   ++ +L
Sbjct: 2417 -QINNLSDNSNHIKEESMINEVKLKSNIDSMNDKILQMQNDSNQLFKENQNLR-NSIDKL 2474

Query: 325  TKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKS-GRNTASKMK 383
             K+I+  E  N  ++QT +        +  E++ +    KK + LI+  +   N    MK
Sbjct: 2475 NKQIKDFEQENESLKQTIQSFTKLNNELTEENEKIY---KKYNDLINNNAVNENNLQVMK 2531

Query: 384  SPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXX 443
               ++   + L    + +++K    + +  I  L  DL +KE +I               
Sbjct: 2532 DQNNKNQIKILELTRNLEMSKFNDDQNKDKINELETDLAEKEKLIKLLQNQLTVSSSDKD 2591

Query: 444  GKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIE 503
             K  ++ Q   E ++  E    I V  N     +I K++E+   + N+ +  +  K+   
Sbjct: 2592 MKQ-ILQQKDEEIRKLNENNGKIKVLQN-----QIEKMKEENNSKTNELLNQL--KESEN 2643

Query: 504  KLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNF-SKVSDSNKEIVRLTE 562
            K  S E +  +L  EI   N +   +K   + K+K+M   I+   S+ SD ++ I+  T+
Sbjct: 2644 KRISLEAEKKKLEIEISNLNIDDNNLKLMEQ-KMKEMSNVINKLQSQESDKDRTIMNQTK 2702

Query: 563  ELHHLSQ---KVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLL 619
            ++  L     K   L+ E   L+  + D +S +   S         +  + ++ K IS L
Sbjct: 2703 QIKKLGSIMTKAKSLKAENTLLRSQISDLESSKTEISSASLNSSSPQMSSLSQKKKISRL 2762

Query: 620  ESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLE-EQIDALSASKKEL 678
            E Q  +L+QE   L+ +         ++  L+++++   IKS+  +  ++  +    K L
Sbjct: 2763 EKQVTELLQENEDLKMEIIHKSTSDENLDSLENEKLQLRIKSLETQLNKMKEIENENKNL 2822

Query: 679  ALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNY--IQENMDLTDKLEKMSAEKISELL 736
               +  ++ + ++L   I+ L     ++   L +   I+EN ++ +K  K    + S+  
Sbjct: 2823 KTKVSFMEENSKKLSSEIESLIKKNGEMKINLVSLKSIKENFEILEKSSKEREAEYSKYR 2882

Query: 737  AKINHEEQSKIQTQFGIDAKIQERDLYIENIES--ELSKYKSRICRLEESIAVMEDRRYS 794
            A    ++ + +QT+     +    DL  EN  +  E+ K  + +   E  +    D   +
Sbjct: 2883 AS-QEKKVNDLQTKLST-LENDYSDLKNENEMNVLEIQKITNNLKLKENQLQRSLDNDKT 2940

Query: 795  LERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKK 854
            ++     L +   E QK  +E  ++ +E+ +    +   +   E+ +  I   N  +QK 
Sbjct: 2941 MDSLQATLNTKTSENQKLSTELVLRNNEIKDLKDEIGKVNNDKEELMKIINVNNTLVQKL 3000

Query: 855  NQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEH 914
             + LL+ N  ++    ++Q++     +K N ++    E      Q+++   +L       
Sbjct: 3001 QKDLLDRNNQIEFLNKEIQENKEEFDQKINESNTKIDELNNIIKQMKETIKSLSNDKDNL 3060

Query: 915  QTLIVQKKKEIEDLEIEF---NTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNI 971
            ++ I   + EI  +  +    + +I   + + + L  + EKN + +  L  +L   K+N 
Sbjct: 3061 KSTIEGNEDEIHRIANKLQKKSNKINFILAENEKLQNEIEKNNKEIENLRKKL---KSNE 3117

Query: 972  ENLNMNVEELNKMNLE---LIDKHVQKQQTQSPDYTEQYINEINKLNA----LLKQKDEE 1024
            E LN N ++ +K +++    I+  ++K+  +  +  +   +E  K N      +KQK+EE
Sbjct: 3118 EKLN-NQQKESKSSIQNHLQINNDLKKENEELSNQLKLKEDEKQKQNEEFDLKIKQKEEE 3176

Query: 1025 IIALNQKINNAQ----VSYMSMVSDYESKLAQ---FTTKLENMEEEMQRVSKQLLDSKQH 1077
            I  L  +I+N Q     +  +++++ E  + +      K++ ++  ++ ++K+L+ S++ 
Sbjct: 3177 ISKLKDEISNLQNKKEEANQNIINEKEELIKENGDLHHKIDELQTNIEDLNKKLISSQRE 3236

Query: 1078 NEEL-QILVREQDDQIKELK---------ETKLTF---EMNIPKTEGMIISSTIEPMSDD 1124
            NE++   L ++ ++ IK  K         + KL     E++    E  I+ S I+  S++
Sbjct: 3237 NEKIINKLKKDLEESIKSQKVQAKLINHRDNKLKENEKEVHSVLLENEILKSDIKKKSNE 3296

Query: 1125 ANNVDXXXXXXXXXXXXLK-----------VQEEEEFIQERS-VLQEQSAKLNTELQECY 1172
             + ++                         +Q++ E +Q ++ +L +   ++  E+ +  
Sbjct: 3297 IDRLNKQYLTSTSITLANDSNLFDRQANNDLQKQIESLQNQNQMLTQNLTRMREEIDQRN 3356

Query: 1173 TKIIQL--ETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAE--LRSS----- 1223
            T+II++  E   T++  +  + +  +N+ K  L +L  EN  L+  + +  LR S     
Sbjct: 3357 TEIIEIKRERTETQINDNSQLKENLLNKEKEIL-RLKNENQELIKEITDKTLRLSEVEKN 3415

Query: 1224 -ISSAVDQRGFEIAELWKQHLAQREADFQKTEHELR---VQLSAFESKYEQLLDSVQSST 1279
             +   +  + +E++   K  L + EA+ +  + EL    V         +  ++++Q + 
Sbjct: 3416 FLKQTISSKDYEMS--MKPKLLELEAENKSLKEELNANEVDNEKILKLKDDEINNLQKAK 3473

Query: 1280 QEETNKIVTMEQVTSLQNKLQDKEE--HLRNLQEKYADVINQIEILRSEIEDEK--VAFX 1335
             +   KIV ME    +  K + KE    L+ ++ +  D+ N++  L  E ED K  ++  
Sbjct: 3474 GDLNLKIVAMENSQKINEKKKVKEIILKLQKMEVENKDLTNRLNDLMKENEDLKRNISDL 3533

Query: 1336 XXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKK--SSXXXXXXXXXXXX 1393
                           +++  N +     E +   +N+E +  +K                
Sbjct: 3534 MKGKSLTEELNKKLDEIKRSNIAISTELEITKQKLNKEESSKRKLMKKIEEQKSLIKKLN 3593

Query: 1394 RVNDAEAKVLE-LTHQLELKDSEIY---QKTHEYTITLTQRNDEFENVRQQLVEYEKRIE 1449
              ND+  K  E    +++  ++ +    +K+ +    L ++N++ E   ++L+EY+K I 
Sbjct: 3594 EENDSLKKSEEDKIGKIKENENNLILETEKSKQKEEDLLKKNNDLE---KKLLEYQKNIA 3650

Query: 1450 DLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELN 1509
            +L  + + E+ +L+ K+++     E   KE      ++I +L   I   + LN+Q+ +LN
Sbjct: 3651 ELNEKHKHEIDLLQSKINDLTKFKEDQTKEIT-NLNQIISQLKNDI---LKLNQQIDDLN 3706

Query: 1510 KALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVS 1559
            +   E+  +  +++T L+ +E++    N   T LQ    A   K+ + +S
Sbjct: 3707 QKFNEKQKECEQIETDLKQKEVK----NKSQTELQ--FEAEKKKLVEQIS 3750



 Score =  147 bits (355), Expect = 3e-33
 Identities = 291/1514 (19%), Positives = 632/1514 (41%), Gaps = 152/1514 (10%)

Query: 102  EILMEKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNALSVL 161
            ++L  +I++ KE +   +  ++                +      +SN +   DN L ++
Sbjct: 2614 KVLQNQIEKMKEENNSKTNELLNQLKESENKRISLEAEKKKLEIEISN-LNIDDNNLKLM 2672

Query: 162  QVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKM 221
            + KMK M   I  LQ + ++KD+ I  + K                    +  K + T +
Sbjct: 2673 EQKMKEMSNVINKLQSQESDKDRTIMNQTKQIKKLGSIMTKA--------KSLKAENTLL 2724

Query: 222  QENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKL--LEAARFEISLEHSKLAQELE 279
            +     +E+  K E       + S   ++SSL +  K+  LE    E+  E+  L  E+ 
Sbjct: 2725 RSQISDLESS-KTEISSA--SLNSSSPQMSSLSQKKKISRLEKQVTELLQENEDLKMEII 2781

Query: 280  QXXXXXXXXXXXXXX---LAKQSIEPSCEEKTEIEEKGS---LEIANMTELTKKIELLEH 333
                              L  +S+E    +  EIE +      +++ M E +KK+     
Sbjct: 2782 HKSTSDENLDSLENEKLQLRIKSLETQLNKMKEIENENKNLKTKVSFMEENSKKLS--SE 2839

Query: 334  LNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSET 393
            +   I++ N E++  L ++ +  +      K      +  S    + + K    Q    T
Sbjct: 2840 IESLIKK-NGEMKINLVSLKSIKENFEILEKSSKEREAEYSKYRASQEKKVNDLQTKLST 2898

Query: 394  LNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEK-------DTXXXXXXXXXXGKD 446
            L  D     N+NE+  LE  IQ +  +L  KE  +          D+             
Sbjct: 2899 LENDYSDLKNENEMNVLE--IQKITNNLKLKENQLQRSLDNDKTMDSLQATLNTKTSENQ 2956

Query: 447  TLIAQLQLEHQQHMEGPSLI-HVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKL 505
             L  +L L + +  +    I  V  + E++ +I  V   L Q+L  ++ D N      ++
Sbjct: 2957 KLSTELVLRNNEIKDLKDEIGKVNNDKEELMKIINVNNTLVQKLQKDLLDRN-----NQI 3011

Query: 506  KSAEEQITQLNDEIDAA-NKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTE-E 563
            +   ++I +  +E D   N++  K+   + + +KQM++TI + S   D+ K  +   E E
Sbjct: 3012 EFLNKEIQENKEEFDQKINESNTKIDELNNI-IKQMKETIKSLSNDKDNLKSTIEGNEDE 3070

Query: 564  LHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQK 623
            +H ++ K   L+++   +   L + +    +++++ K   E+ENL +        L +Q+
Sbjct: 3071 IHRIANK---LQKKSNKINFILAENEK---LQNEIEKNNKEIENLRKKLKSNEEKLNNQQ 3124

Query: 624  FDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIE 683
             +    +    Q + ++ + L    + +++++ +++K   L+E  D      +E  L I+
Sbjct: 3125 KESKSSI----QNHLQINNDL----KKENEELSNQLK---LKE--DEKQKQNEEFDLKIK 3171

Query: 684  NLKLDKEQLYGTIKDLENDKED----IMNKLQNYIQENMDLTDKLEKMSAEKISELLAKI 739
              + +  +L   I +L+N KE+    I+N+ +  I+EN DL  K++++    I +L  K+
Sbjct: 3172 QKEEEISKLKDEISNLQNKKEEANQNIINEKEELIKENGDLHHKIDELQTN-IEDLNKKL 3230

Query: 740  --NHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLER 797
              +  E  KI  +   D    E  +  + ++++L  ++    +L+E+    E   +S+  
Sbjct: 3231 ISSQRENEKIINKLKKDL---EESIKSQKVQAKLINHRDN--KLKEN----EKEVHSVLL 3281

Query: 798  KADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLL-EIEHENKELQKKNQ 856
            + + L S +++K        + +  L +    L +   + ++Q   +++ + + LQ +NQ
Sbjct: 3282 ENEILKSDIKKKSNEIDR--LNKQYLTSTSITLANDSNLFDRQANNDLQKQIESLQNQNQ 3339

Query: 857  ILLEENQNLQISLSDMQQHYNALVE-KANRTDLAESESTKYQTQLRDLESNLKRITHEHQ 915
            +L    QNL     ++ Q    ++E K  RT+   +++++ +  L + E  + R+ +E+Q
Sbjct: 3340 ML---TQNLTRMREEIDQRNTEIIEIKRERTETQINDNSQLKENLLNKEKEILRLKNENQ 3396

Query: 916  TLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIE-YVTQLEAQLQEYKNNIENL 974
             LI    KEI D  +  + ++E     + + ++ YE +++  + +LEA+ +  K   E L
Sbjct: 3397 ELI----KEITDKTLRLS-EVEKNFLKQTISSKDYEMSMKPKLLELEAENKSLK---EEL 3448

Query: 975  NMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINN 1034
            N N E  N+  L+L D  +   Q    D   + +   N      K+K +EII   QK+  
Sbjct: 3449 NAN-EVDNEKILKLKDDEINNLQKAKGDLNLKIVAMENSQKINEKKKVKEIILKLQKMEV 3507

Query: 1035 AQVSYMSMVSDYESKLAQFTTKLENM---EEEMQRVSKQLLDSKQHNEELQILVREQDDQ 1091
                  + ++D   +       + ++   +   + ++K+L + K+ N  +   +     +
Sbjct: 3508 ENKDLTNRLNDLMKENEDLKRNISDLMKGKSLTEELNKKLDEIKRSNIAISTELEITKQK 3567

Query: 1092 IKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFI 1151
            + + + +K      I + + +I    +   +D     +              + E E+  
Sbjct: 3568 LNKEESSKRKLMKKIEEQKSLI--KKLNEENDSLKKSEEDKIGKIKENENNLILETEKSK 3625

Query: 1152 QERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDV-VNQEQINQLKSKLEQLNTEN 1210
            Q+   L +++  L  +L E    I +L     E   H++ + Q +IN L    E    E 
Sbjct: 3626 QKEEDLLKKNNDLEKKLLEYQKNIAELN----EKHKHEIDLLQSKINDLTKFKEDQTKEI 3681

Query: 1211 DNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQ 1270
             NL   +++L++ I     Q    I +L  Q   +++ + ++ E +L         K ++
Sbjct: 3682 TNLNQIISQLKNDILKLNQQ----IDDL-NQKFNEKQKECEQIETDL---------KQKE 3727

Query: 1271 LLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDE 1330
            + +  Q+  Q E  K   +EQ++SL N++         L+E    +I +++ L  E + +
Sbjct: 3728 VKNKSQTELQFEAEKKKLVEQISSLNNEIMSLTNDKAKLEEDQQKLIKKLKKLNEEYQSK 3787

Query: 1331 KVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNIN--EENAQLKKSSXXXXXXX 1388
            +  +                 ++T   +Y+   ++  + I   E   +L K         
Sbjct: 3788 RSDY--------------EFQIKTITNNYEDEIQKLKVTIKKLENELELLKIENEKINGI 3833

Query: 1389 XXXXXRVNDAEAKVLELTHQLELKD-SEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKR 1447
                 + N+   K +      +L+D S    K +E  +T+ +   E  ++R Q  E    
Sbjct: 3834 LQAREKTNEKLRKSIS-----DLRDSSNDDSKYNEMKLTIAKLKSELNSLRNQSKE-NSS 3887

Query: 1448 IEDLTYEKESELAILRLKM--HENANHYETMQKESEIERVKLIEEL--NVKITESVSLNK 1503
            I D   EK  ++A    K+  +  +   + ++ +S  E ++++  +  + K+   V  +K
Sbjct: 3888 ISDDKLEKYKQIAKRAQKVLSYAASLREKVIETQSITECLEILNSIFVSAKLERVVLKSK 3947

Query: 1504 QVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASD 1563
             +    K+L+  +++   +   +      +V  ++ I +L + V+     + +  S   D
Sbjct: 3948 SIESPKKSLQSAISEIQRIFPCVS----AVVEPSENIHSLDDQVQV----LHQQFSLLRD 3999

Query: 1564 TKQGRDEQLDNTMN 1577
                R++ +DN  N
Sbjct: 4000 VFDNREKTVDNLGN 4013



 Score =  141 bits (342), Expect = 1e-31
 Identities = 270/1464 (18%), Positives = 618/1464 (42%), Gaps = 116/1464 (7%)

Query: 151  IKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXX 210
            +K+K+N L+       I+ET   +++  +N+   +++ +                     
Sbjct: 2232 LKQKENDLTTAN---SIIETLKNEIENTMNKSSILVQNE---MNKKDEIIQNLQEQLSNL 2285

Query: 211  XEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEIS-L 269
             ++T ++++K+Q +        K+ +  LL  I+SK+  I++L+E N+  +    ++   
Sbjct: 2286 KQETNEEISKLQND--------KNNQTELLNLIKSKNDEINNLKEINRQKDQQIMDLKRY 2337

Query: 270  EHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEK---GSLEIANMTELTK 326
            E ++L                       +S+    +E ++I EK     L+  +M +  +
Sbjct: 2338 EQTELLNLSNNDDQNRSSSIVYNSSTLMKSLR-QVKEDSQIREKFIDDQLKSLSMQK-DE 2395

Query: 327  KIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRK--SGRNTASKMKS 384
            +I+ L++ N +  +  ++LE ++  +   S  +   S      +     S  +   +M++
Sbjct: 2396 EIKNLQNKNSEKDEKIRDLEKQINNLSDNSNHIKEESMINEVKLKSNIDSMNDKILQMQN 2455

Query: 385  PWSQLSSETLN-QDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISE--KDTXXXXXXXX 441
              +QL  E  N +++  K+NK +I   E   +SL + +     + +E  ++         
Sbjct: 2456 DSNQLFKENQNLRNSIDKLNK-QIKDFEQENESLKQTIQSFTKLNNELTEENEKIYKKYN 2514

Query: 442  XXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDL 501
                +  + +  L+  +     + I +   T ++       +Q K ++N+   D+  K+ 
Sbjct: 2515 DLINNNAVNENNLQVMKDQNNKNQIKILELTRNLEMSKFNDDQNKDKINELETDLAEKEK 2574

Query: 502  IEKLKSAEEQITQLNDE----IDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEI 557
            + KL   +  ++  + +    +   ++ + K+  N+  K+K +Q  I+   +  ++N + 
Sbjct: 2575 LIKLLQNQLTVSSSDKDMKQILQQKDEEIRKLNENNG-KIKVLQNQIEKMKE--ENNSKT 2631

Query: 558  VRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAIS 617
              L  +L     K   LE EK  L++ + + +        + +KM EM N+        S
Sbjct: 2632 NELLNQLKESENKRISLEAEKKKLEIEISNLNIDDNNLKLMEQKMKEMSNVINKLQSQES 2691

Query: 618  LLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKE 677
              +    +  +++  L     + +   A+ + L+S    S+++S   E    +L++S  +
Sbjct: 2692 DKDRTIMNQTKQIKKLGSIMTKAKSLKAENTLLRSQ--ISDLESSKTEISSASLNSSSPQ 2749

Query: 678  LALVIENLKLDK--EQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISEL 735
            ++ + +  K+ +  +Q+   +++ E+ K +I++K  +   EN+D  +  EK+   +I  L
Sbjct: 2750 MSSLSQKKKISRLEKQVTELLQENEDLKMEIIHKSTS--DENLDSLEN-EKLQL-RIKSL 2805

Query: 736  LAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSL 795
              ++N  ++ + + +  +  K+   +   + + SE+     +   ++ ++  ++    S+
Sbjct: 2806 ETQLNKMKEIENENK-NLKTKVSFMEENSKKLSSEIESLIKKNGEMKINLVSLK----SI 2860

Query: 796  ERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENK----EL 851
            +   + L    +E++  YS+Y   +++ VN L   +     +E    ++++EN+    E+
Sbjct: 2861 KENFEILEKSSKEREAEYSKYRASQEKKVNDLQTKLS---TLENDYSDLKNENEMNVLEI 2917

Query: 852  QK-KNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRI 910
            QK  N + L+ENQ LQ SL D  +  ++L    N      SE+ K  T+L    + +K +
Sbjct: 2918 QKITNNLKLKENQ-LQRSL-DNDKTMDSLQATLNTKT---SENQKLSTELVLRNNEIKDL 2972

Query: 911  THEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVT-QLEAQLQEYKN 969
              E   +   K++ ++ + +  NT ++   +D    N +    IE++  +++   +E+  
Sbjct: 2973 KDEIGKVNNDKEELMKIINVN-NTLVQKLQKDLLDRNNQ----IEFLNKEIQENKEEFDQ 3027

Query: 970  NIENLNMNVEELNKMNLELID--KHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEI-- 1025
             I   N  ++ELN +  ++ +  K +   +       E   +EI+++   L++K  +I  
Sbjct: 3028 KINESNTKIDELNNIIKQMKETIKSLSNDKDNLKSTIEGNEDEIHRIANKLQKKSNKINF 3087

Query: 1026 -IALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLL----DSKQHNEE 1080
             +A N+K+ N        + +   KL     KL N ++E +   +  L    D K+ NEE
Sbjct: 3088 ILAENEKLQNEIEKNNKEIENLRKKLKSNEEKLNNQQKESKSSIQNHLQINNDLKKENEE 3147

Query: 1081 LQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXX 1140
            L   ++ ++D+ ++  E    F++ I + E       I  + D+ +N+            
Sbjct: 3148 LSNQLKLKEDEKQKQNEE---FDLKIKQKE-----EEISKLKDEISNLQNK--------- 3190

Query: 1141 XLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLK 1200
              K +  +  I E+  L +++  L+ ++ E  T I   E LN +L      N++ IN+LK
Sbjct: 3191 --KEEANQNIINEKEELIKENGDLHHKIDELQTNI---EDLNKKLISSQRENEKIINKLK 3245

Query: 1201 SKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHEL-RV 1259
              LE    E+       A+L +   + + +   E+  +  ++   + +D +K  +E+ R+
Sbjct: 3246 KDLE----ESIKSQKVQAKLINHRDNKLKENEKEVHSVLLENEILK-SDIKKKSNEIDRL 3300

Query: 1260 QLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQ 1319
                  S    L +      ++  N +   +Q+ SLQN+ Q   ++L  ++E+      +
Sbjct: 3301 NKQYLTSTSITLANDSNLFDRQANNDL--QKQIESLQNQNQMLTQNLTRMREEIDQRNTE 3358

Query: 1320 IEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKK 1379
            I  ++ E  + ++                   L+ ENQ   +      L ++E      K
Sbjct: 3359 IIEIKRERTETQINDNSQLKENLLNKEKEILRLKNENQELIKEITDKTLRLSEVEKNFLK 3418

Query: 1380 SSXXXXXXXXXXXXRVNDAEAKVLELTHQLELK--DSEIYQKTHEYTITLTQRNDEFENV 1437
             +            ++ + EA+   L  +L     D+E   K  +  I   Q+     N+
Sbjct: 3419 QTISSKDYEMSMKPKLLELEAENKSLKEELNANEVDNEKILKLKDDEINNLQKAKGDLNL 3478

Query: 1438 RQQLVEYEKRIEDLTYEKESELAILRLKMHEN--ANHYETMQKESEIERVKLIEELNVKI 1495
            +   +E  ++I +    KE  L + ++++      N    + KE+E        +L   I
Sbjct: 3479 KIVAMENSQKINEKKKVKEIILKLQKMEVENKDLTNRLNDLMKENE--------DLKRNI 3530

Query: 1496 TESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQ 1555
            ++ +       ELNK L+E       + T LE  + ++         L   +    S I+
Sbjct: 3531 SDLMKGKSLTEELNKKLDEIKRSNIAISTELEITKQKLNKEESSKRKLMKKIEEQKSLIK 3590

Query: 1556 KHVSFASDTKQGRDEQLDNTMNKE 1579
            K        K+  ++++      E
Sbjct: 3591 KLNEENDSLKKSEEDKIGKIKENE 3614



 Score =  140 bits (340), Expect = 2e-31
 Identities = 209/1065 (19%), Positives = 474/1065 (44%), Gaps = 101/1065 (9%)

Query: 569  QKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISL---LESQKFD 625
            Q+  EL +E  NL+ ++ + +  + IES +  K+ E +N  +T+ +   +    E+ K +
Sbjct: 199  QEAEELTQENDNLRENIENLN--KEIES-LQNKIKENQNTPQTQQQYEEMKKKYENLKIE 255

Query: 626  LVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENL 685
               +  ++ Q+ DE+     +I +LQ + +  ++ +    + I   S  K      I NL
Sbjct: 256  NNSQKILIDQRTDELTKARQEIGKLQQELMGDDLPNDKAFKDIYKESQEK------IVNL 309

Query: 686  KLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQS 745
            + +  QL   +++ + ++E++  KL N +  N++    L K   ++I++L  ++    Q 
Sbjct: 310  QTENNQLKKDLENAKTEQENLNQKLNN-LNNNLNDNSLLNKSLNDQINQLKVEL----QK 364

Query: 746  KIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQ---- 801
               T +  D  +QE+D  IE ++  L+  K+    LEE+   +++   +   K+D     
Sbjct: 365  MQNTIYKKDGDLQEKDDEIEQLKQTLNAQKTFSNELEETNKKLKEM-LNQNSKSDLTNSS 423

Query: 802  -LGSYLQEKQKAYSEYTIQEDE-LVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILL 859
             L S+   KQ+     T QE+E L N+L  L       ++QLL ++ EN+ L++K     
Sbjct: 424  FLSSFNLTKQRLND--TKQENEQLQNQLMQL-------QQQLLILKQENENLKEKQNSYS 474

Query: 860  EENQN------LQISLSDMQQHYNALVEK-ANRTDLAESESTKYQTQLRDLESNLKRITH 912
            +   N      L IS SD  Q   A++++   R        ++ + ++   E++ K    
Sbjct: 475  DSLNNSSNMSALDISGSDFVQIDQAIIDQYEQRIKSLTDNISELREKISQKENSEKSNDS 534

Query: 913  EHQTLIVQKKKEI-----EDLEI-EFNTQIESAIRDKK--------VLNEKYEKNIEYV- 957
            +    ++Q KK +     E+  I E N ++   + + K        +LN+   K I+ + 
Sbjct: 535  QRSLELIQLKKSLDKAKKENYSIKEENFKLNQLLNNYKRKIDNLNQLLNDLNPKEIKLLL 594

Query: 958  TQLEAQ-----------LQEYKNNIEN-LNMNVEELNKMNLELIDKHVQKQQTQSPDYT- 1004
            + L+             +++ KN + N L+ N + +  +  EL++   + Q +++ +   
Sbjct: 595  SSLKKDFLLKRDDFIKYIRKAKNEVRNALSENSDLIENLQNELLNMKEKLQNSKAENKQI 654

Query: 1005 ---EQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENME 1061
               +  IN++NK+   +++++E +   N++ NN          +  S   +  T+ + ++
Sbjct: 655  LSLQPKINDLNKIMTQIQKENERLQKTNKEKNNEIEKLKDENENLVSNNKKLQTENKELK 714

Query: 1062 EEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPM 1121
            E +++ + Q  D    N +L   + E  +QIK L + K      + K     +S+ ++ +
Sbjct: 715  ENLEKETSQNSDLLNENSDLNDKLNELRNQIKTLNDDKTKQNQLLQKN----LSNQLKDL 770

Query: 1122 SDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETL 1181
             D+ N++             L+   ++   Q  S  +E  +K+N +  E      +L +L
Sbjct: 771  LDENNSLKDQLAQLQSSNNQLQKDIKDLTRQNESKTKELQSKINEKENENQNLTEKLNSL 830

Query: 1182 NTELTGHDVVNQEQINQLKSKLEQLN-TENDNLLSTVAELRSSISSAVDQRGFEIAELWK 1240
             +++      N++  N ++S    LN ++N+N      EL+        ++  +I +   
Sbjct: 831  QSQIQILQNGNEDLQNDIESITNALNQSQNEN-----KELKEENQKI--EKSNQILQYEN 883

Query: 1241 QHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQ 1300
            + + +++   Q    +L+ Q S  ++K ++L + + S  +E++N      Q    Q  L+
Sbjct: 884  KEVKEQKEKLQNQIDDLKNQNSNLQNKVDELNEEISSINEEKSN------QEKEYQEMLK 937

Query: 1301 DKEEHLRNLQEKYADVINQI-EILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSY 1359
            D E  L+NL+ +  +   +I EIL  +   +                      + +N+  
Sbjct: 938  DLETKLKNLEAERLESNKEITEILELDTTFDDSTISDHLRKQCEQLKSLIEQNKNQNEEI 997

Query: 1360 KQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQK 1419
            + ++ Q+  ++  +N ++KK                 D + ++ +L  ++E   SEI   
Sbjct: 998  QNLKSQN-EDLTVKNEEMKKELMNNQTTICDLIKTSEDKDKEIDDLKQKIEKLKSEIDNS 1056

Query: 1420 THEYTITLTQ-RNDEFENVRQQLV---EYEKRIEDLTYEKESELAILRLKMHENANHYET 1475
              +   TLT+ +   F+ ++ Q+    + +K++E      + E   +++K+    N  ++
Sbjct: 1057 KKQLDTTLTEFKVSNFDELQSQISRNNDDKKKLEQKVQNLQKENEEMKIKLENKENERKS 1116

Query: 1476 MQKESEIERVKLIEELNVKITESVSLNK-QVAELNKALEEEVAKTNEMQTALENQEIEIV 1534
            +   S +E   ++  L  K+  +  L++ Q+ EL K ++      +++   +++   E +
Sbjct: 1117 L---SSLESENIL--LKQKLQNNDKLHQIQIGELQKEIDVLNQTKSKLSKEVDDITNENI 1171

Query: 1535 TLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKE 1579
            TL ++I    +M    +++++K ++           QL+ ++ KE
Sbjct: 1172 TLKNQINTTFSMSIDENNELKKKLNQLIKENNSYQLQLNQSVPKE 1216


>UniRef50_A2EN31 Cluster: Viral A-type inclusion protein, putative;
            n=1; Trichomonas vaginalis G3|Rep: Viral A-type inclusion
            protein, putative - Trichomonas vaginalis G3
          Length = 5296

 Score =  196 bits (479), Expect = 3e-48
 Identities = 274/1470 (18%), Positives = 610/1470 (41%), Gaps = 75/1470 (5%)

Query: 149  NTIKEKDNALSVLQVKMKIMETTILDLQEKI-NEKDQIIEAKNKATTXXXXXXXXXXXXX 207
            ++  ++ N L   + K++I  T + D +  + NEK Q+ +  N                 
Sbjct: 3360 DSANDEKNKLEQDKHKLEIDNTKLNDAKSHLENEKSQLAQQINDLNNKLQKLEEEKNKL- 3418

Query: 208  XXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEI 267
                E+ K Q  K  EN      +   + Q LLK +E    ++   E+    LE  + EI
Sbjct: 3419 ----EEEKAQNEKKLENSQQDGDKLGQQNQDLLKQLEEIKQKLQQTEQEKSALEQQKNEI 3474

Query: 268  SLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKK 327
              + +++ Q+++                 KQ ++   +EK+E ++K         E+  K
Sbjct: 3475 QNKLNEIEQQMKDSEKEKEDI--------KQKLQQVEQEKSETQKKLEEAEQQKNEIQNK 3526

Query: 328  IELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWS 387
            +E  E     +     E E +L       K +++   +    +         ++ K   +
Sbjct: 3527 LEQTEQEKKNLENEKAETEKRLQETEEAKKNLANEKSEAERKLEEVQNEKAETERKLNEA 3586

Query: 388  QLSSETLNQD---TDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXG 444
            + +++ L  +   T KK+ + E  K E   + L +    K+ + +EK             
Sbjct: 3587 EEANKNLENEKNETQKKLEEAEQQKAETQ-KLLEQTEEAKKNLANEKSEAERKLQETEEA 3645

Query: 445  KDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEK 504
            K  L A  + E ++ +E        T  + +NE  +  + L+ E N+  K       +E+
Sbjct: 3646 KKNL-ANEKSEAERKLEEVQNEKAETERK-LNEAEEANKNLENEKNETQKK------LEE 3697

Query: 505  LKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFS-KVSDSNKEIVRLTEE 563
             +  + +  +L ++ + A KN+   KS  + KL++ ++   N + + S++ +++  +  E
Sbjct: 3698 AEQQKAETQKLLEQTEEAKKNLANEKSEAERKLQETEEAKKNLANEKSEAERKLEEVQNE 3757

Query: 564  LHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQK 623
                 +K+ E EE   NL+      ++ + +E    +K  E + L E   +A   LE++K
Sbjct: 3758 KAETERKLNEAEEANKNLENE--KNETQKKLEEAEQQKA-ETQKLLEQTEEAKKNLENEK 3814

Query: 624  FDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIE 683
             +  ++L   ++    +E + +DI +   +    ++   + + +   L    +E    +E
Sbjct: 3815 SETEKKLQETEEAKKNLEQEKSDIQKKLDETKQQKVNLENEKAETQKLLEETEEAKKNLE 3874

Query: 684  NLKLDKEQ-LYGTI---KDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKI 739
            N K + E+ L  T    K+L N+K +   KL+    E  +   KL +  AE+ ++ L   
Sbjct: 3875 NEKAETEKRLQETEEAKKNLANEKSEAERKLEEVQNEKAETERKLNE--AEEANKNLENE 3932

Query: 740  NHEEQSKI----QTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSL 795
             +E Q K+    Q +      +++ +   +N+E+E S+ + ++   EE+   +E  +  +
Sbjct: 3933 KNETQKKLEEAEQQKAETQKLLEQTEEAKKNLENEKSETEKKLQETEEAKKNLEQEKSDI 3992

Query: 796  ERKADQLGSYLQ--EKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQK 853
            ++K D+        E +KA ++  ++E E   +   L +     +K+L E E   K L++
Sbjct: 3993 QKKLDETKQQKVNLENEKAETQKLLEETEEAKKN--LENEKAETQKKLDEAEEAKKNLEQ 4050

Query: 854  KN---QILLEENQNLQISLSDMQQHYNALVEKANRT-DLAESESTKYQTQLRDLESNLKR 909
            +    +  LEE QN + +L + +      +E+A +  D    E +  + QL + + +   
Sbjct: 4051 EKSDAEKKLEEVQNEKSALENEKNETQKKLEEAEKAKDQIVEEKSAVERQLVESQKDSSE 4110

Query: 910  ITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKN 969
               +      + ++++ DL+ + N  +E  + DK+  NEK ++  +    L+ QL + + 
Sbjct: 4111 NQKQQDEEKSKLQQQLSDLQNKLN-DLEKKLADKE--NEKEQEKTQK-DDLQKQLDQLQK 4166

Query: 970  NIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYT-EQYINEINKLNALLKQKDEEIIAL 1028
            + +NL    ++L   N  + +    K        T + ++N+ N  N  L+ ++ ++   
Sbjct: 4167 DFDNLEREKQKLQDKNDSMKETIDSKNMLLDSFGTIKDHLNDANNNNKKLQDENNKLRDD 4226

Query: 1029 NQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQ 1088
             QK  +      S++ D   KLA    + +  EE+++    +L  ++   +  +  +RE 
Sbjct: 4227 AQKATSKNNELQSIIDDLNRKLANLDAEKKATEEKLKNTEDKLKQAEAEKKATEDKLRET 4286

Query: 1089 DDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEE 1148
            ++  KE +E     E    + E  + ++       +                   V+ E+
Sbjct: 4287 ENAKKETEEKLAKTEEEKKQVEDKLAATEAAKKETEDKLKQTEDEKKATEDKLANVEAEK 4346

Query: 1149 EFIQERSVLQEQSAKLNTELQ---ECYTKIIQLETLNTELTGHDVVNQ-EQINQLKSKLE 1204
              I++     E   K   E +   E   K  + +   TE    +  ++ +Q    K+ +E
Sbjct: 4347 SDIEQAKKETEDKLKQTEEEKAAVEAEKKATEDKLHETEEAKKETEDKLKQTEDEKAAVE 4406

Query: 1205 QLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAF 1264
            Q   E ++ L    E + +  + +++   E  EL ++  + R +  +K   +L   LS  
Sbjct: 4407 QAKKETEDKLKQTEEEKKATENKLEESEAEKKELGERFESSRGST-EKQVSDLENLLSKL 4465

Query: 1265 ESKYEQLLDS---VQSST-QEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQ- 1319
            + + + + +    ++S   Q E  K  T +++   + +    E+  +  ++K A+V N+ 
Sbjct: 4466 KDELKNIKEDKSQLESKLKQAEAEKKATEDKLAKTEVEKAALEQAKKETEDKLANVENEK 4525

Query: 1320 --IEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQ-EQSILNINEENAQ 1376
               E  ++++  EK                   + +   +    ++ E+        NA+
Sbjct: 4526 KATETQKNDLAKEKTDLQKALAKLLKRQEQLDAEKKALEEKANALESEKKATEEKLANAE 4585

Query: 1377 LKKSSXXXXXXXXXXXXRVNDAEAKVLE-LTHQLELKDSEIYQKTHEYTITLTQRNDEFE 1435
             +K                +++E K  E    Q E + ++I     E    L    +E +
Sbjct: 4586 KEKKETQDKLKQTEDNLAKSESEKKATEDKLKQTESEKAQIEAAKKETEDKLQNAENEKK 4645

Query: 1436 NVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKI 1495
               ++L + E++ +  T EK  E    +    E   + E  +++      K + +L+ +I
Sbjct: 4646 AAEEKLKQSEEQ-KKATEEKLQEAEAEKKAEQEKLANIEAEKQQLGNASEKQVSDLSGEI 4704

Query: 1496 TESVSLNKQVAELNKALEEEVAKTNEMQTALENQ----EIEIVTLNDEITNLQNMVRASS 1551
            ++   L KQ+AE  K  +EE+AK+ + +   +N     + ++  L  ++ +L+   + S 
Sbjct: 4705 SKLKQLLKQLAEAKKKADEELAKSKQDKEQSDNDKSKLQEDLNNLKKQLEDLEKAKKESD 4764

Query: 1552 SK---IQKHVSFASDTKQGRDEQLDNTMNK 1578
            S    +   V+   +  + +D+++ N  +K
Sbjct: 4765 SNNKLLADSVNKLKEQNKQKDDEIKNLTDK 4794



 Score =  188 bits (457), Expect = 1e-45
 Identities = 266/1383 (19%), Positives = 594/1383 (42%), Gaps = 108/1383 (7%)

Query: 233  KDEKQRLLKDIES--KDVRISSLE-EANKLLEAARFEISLEHSKLAQELEQXXXXXXXXX 289
            K E QRL  ++E    +  +SS + E  K +E    E+  + + L+ E +Q         
Sbjct: 2957 KLENQRLNSELEKLKSNQPVSSNDPELQKQIE----ELKKQLNNLSNEKKQIETEKNGLQ 3012

Query: 290  XXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKL 349
                 L  Q+ E   E K +++E+     A M E+ ++   L     Q+ +TN  LENK+
Sbjct: 3013 GQIGRLESQN-ESLIESKKDMKEQNDKLQAQMDEMRRENNSLRQNQTQLERTNNGLENKV 3071

Query: 350  ATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAK 409
              +  +   V +        +  K   N   K+++   +L++E  + +   K    EI K
Sbjct: 3072 GNLTDQLNQVKNQLSALQDQLKSKENEN--EKLRNEREKLANEKNSVELQSKDKDAEIIK 3129

Query: 410  LEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVG 469
            L+   + LN    DK   ++++              D L  Q++   QQ     +L +  
Sbjct: 3130 LKSDAEHLN----DKINSLNDEKNKLQQA------NDKLNDQIEQMKQQIN---NLTNEN 3176

Query: 470  TNTEDVNEIAKVQEQLKQELNDEIKDVNV-KDLIEKLKSAEE-QITQLNDEIDAANKNMI 527
             N E   E AK QE++ Q +  ++K +   K  +E   S  E +I +L D I   +  + 
Sbjct: 3177 KNMEQ--EKAKNQEKI-QNIEPKLKQLEEEKSKLEDENSQNENEIQRLKDTIKELSDKLA 3233

Query: 528  KVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVD 587
            K + ++KL  +    T D   +V D  + + +L ++L +L+ +  +L+++K  L      
Sbjct: 3234 KSEEDNKLLKQSSSGTTDK--QVEDLQEMLNKLRDDLKNLNSENEQLKQQKDQL------ 3285

Query: 588  YDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADI 647
              S ++  S+  K   E +N  E   K +  L ++K  +  +     Q   +VE     +
Sbjct: 3286 --SEKLNNSNNDKTKAETQN--EQLSKQLEQLNNEKNQMFNKYKNAIQDKAKVEIAKETL 3341

Query: 648  SQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIM 707
            ++  ++++ SE +S  L++++D+ +  K +L      L++D  +L      LEN+K  + 
Sbjct: 3342 AK-DNEKLASEKES--LQQKLDSANDEKNKLEQDKHKLEIDNTKLNDAKSHLENEKSQLA 3398

Query: 708  NKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENI 767
             ++        DL +KL+K+  EK      K  +E++ +   Q G     Q +DL     
Sbjct: 3399 QQIN-------DLNNKLQKLEEEKNKLEEEKAQNEKKLENSQQDGDKLGQQNQDLL---- 3447

Query: 768  ESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRL 827
              +L + K ++ + E+  + +E ++  ++ K +++   +++ +K       +++++  +L
Sbjct: 3448 -KQLEEIKQKLQQTEQEKSALEQQKNEIQNKLNEIEQQMKDSEK-------EKEDIKQKL 3499

Query: 828  AVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSD----MQQHYNALVEKA 883
              +       +K+L E E +  E+Q K +   +E +NL+   ++    +Q+   A    A
Sbjct: 3500 QQVEQEKSETQKKLEEAEQQKNEIQNKLEQTEQEKKNLENEKAETEKRLQETEEAKKNLA 3559

Query: 884  NRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDK 943
            N    AE +  + Q +  + E  L      ++ L  +K +  + LE     + E+    +
Sbjct: 3560 NEKSEAERKLEEVQNEKAETERKLNEAEEANKNLENEKNETQKKLEEAEQQKAET----Q 3615

Query: 944  KVL--NEKYEKNI-EYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDK--HVQKQQT 998
            K+L   E+ +KN+    ++ E +LQE +   +NL     E  +   E+ ++    +++  
Sbjct: 3616 KLLEQTEEAKKNLANEKSEAERKLQETEEAKKNLANEKSEAERKLEEVQNEKAETERKLN 3675

Query: 999  QSPDYTEQYINEINKLNALLKQKDE---EIIALNQKINNAQVSYMSMVSDYESKLAQFTT 1055
            ++ +  +   NE N+    L++ ++   E   L ++   A+ +  +  S+ E KL +   
Sbjct: 3676 EAEEANKNLENEKNETQKKLEEAEQQKAETQKLLEQTEEAKKNLANEKSEAERKLQETEE 3735

Query: 1056 KLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIIS 1115
              +N+  E     ++L + +    E +  + E ++  K L+  K   +  + + E     
Sbjct: 3736 AKKNLANEKSEAERKLEEVQNEKAETERKLNEAEEANKNLENEKNETQKKLEEAEQQKAE 3795

Query: 1116 S--TIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYT 1173
            +   +E   +   N++             K+QE EE    +  L+++ + +  +L E   
Sbjct: 3796 TQKLLEQTEEAKKNLENEKSETEK-----KLQETEE---AKKNLEQEKSDIQKKLDETKQ 3847

Query: 1174 KIIQLETLNTE---LTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQ 1230
            + + LE    E   L       ++ +   K++ E+   E +     +A  +S     +++
Sbjct: 3848 QKVNLENEKAETQKLLEETEEAKKNLENEKAETEKRLQETEEAKKNLANEKSEAERKLEE 3907

Query: 1231 RGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTME 1290
               E AE  ++ L + E   +  E+E        E   +Q  ++ +   Q E  K     
Sbjct: 3908 VQNEKAET-ERKLNEAEEANKNLENEKNETQKKLEEAEQQKAETQKLLEQTEEAKKNLEN 3966

Query: 1291 QVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSE---IEDEKVAFXXXXXXXXXXXXX 1347
            + +  + KLQ+ EE  +NL+++ +D+  +++  + +   +E+EK A              
Sbjct: 3967 EKSETEKKLQETEEAKKNLEQEKSDIQKKLDETKQQKVNLENEK-AETQKLLEETEEAKK 4025

Query: 1348 XXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLE--- 1404
               + + E Q      E++  N+ +E +  +K                N+ + K+ E   
Sbjct: 4026 NLENEKAETQKKLDEAEEAKKNLEQEKSDAEKKLEEVQNEKSALENEKNETQKKLEEAEK 4085

Query: 1405 ----LTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDL---TYEKES 1457
                +  +    + ++ +   + +    Q+++E   ++QQL + + ++ DL     +KE+
Sbjct: 4086 AKDQIVEEKSAVERQLVESQKDSSENQKQQDEEKSKLQQQLSDLQNKLNDLEKKLADKEN 4145

Query: 1458 ELAILRLKMHENANHYETMQKE-SEIERVK-LIEELNVKITESVSLNKQVAELNKALEEE 1515
            E    + +  +     + +QK+   +ER K  +++ N  + E++     + +    +++ 
Sbjct: 4146 EKEQEKTQKDDLQKQLDQLQKDFDNLEREKQKLQDKNDSMKETIDSKNMLLDSFGTIKDH 4205

Query: 1516 VAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNT 1575
            +   N     L+++  ++     + T+  N +++    + + ++     K+  +E+L NT
Sbjct: 4206 LNDANNNNKKLQDENNKLRDDAQKATSKNNELQSIIDDLNRKLANLDAEKKATEEKLKNT 4265

Query: 1576 MNK 1578
             +K
Sbjct: 4266 EDK 4268



 Score =  176 bits (428), Expect = 5e-42
 Identities = 287/1465 (19%), Positives = 609/1465 (41%), Gaps = 99/1465 (6%)

Query: 149  NTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXX 208
            N  KEK      ++   K ++ TI  L+ +++ + +   +K  +                
Sbjct: 2608 NYEKEKAEREKEVEENNKKLKDTINALENRLDSQGEQTRSKINSAEQTARKAKEDADSAV 2667

Query: 209  XXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLL------EA 262
               +  + ++  +++ +  +E + K EK+   +  E++ ++  + E+A  ++      E 
Sbjct: 2668 IAQKSLQAELNNLKQKYAVLEDQLKTEKENHQQ--EAQQLKELAEEDATPMVCIHVVGEK 2725

Query: 263  ARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMT 322
             + ++  ++ KL++  +               L KQ  + + E      + G+L+    T
Sbjct: 2726 LK-KLQNDNEKLSENNDNLQKNINELKDKINGLEKQYKQDAAELSNVHHQLGALQ-EKAT 2783

Query: 323  ELTKKIELLEHLNCQIRQTNKELEN-KLATMGTESKAVSSPSKKGSPLISRKSGRNTASK 381
             L  + + L+  N  +   NK+LE  K   +   S    + + +   L++RK   +   K
Sbjct: 2784 NLENENKSLKEENEDLMNQNKQLEKEKQQLLAQNSNLEENKNNQEQSLMNRKKKNDDLLK 2843

Query: 382  MKSPWSQLSSETLNQDTDKKINK--NEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXX 439
                  +L  E L ++  +   K  N   ++EM+   +N D   KE + S +D       
Sbjct: 2844 QIDDL-KLELEELKRNNSQNETKLQNANQQIEMMKDQINND---KEQIKSAQDKLNDLQN 2899

Query: 440  XXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVK 499
                  +    Q+ LE+Q+ M       + ++ + +N+     E  K+   D+I D+  +
Sbjct: 2900 K---NNELNSNQIVLENQKKMYEGLYNDMKSSNDKLND-----ENRKK--TDQIIDLTKQ 2949

Query: 500  DLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVR 559
            +        E Q  +LN E++    N   V SN     KQ+++     + +S+  K+I  
Sbjct: 2950 NAEVSALKLENQ--RLNSELEKLKSNQ-PVSSNDPELQKQIEELKKQLNNLSNEKKQI-- 3004

Query: 560  LTEELHHLSQKVAELEEEKGNLQLHLVDY-DSGRMIESDVYKKMIEMENLAE--TRLKAI 616
               E + L  ++  LE +  +L     D  +    +++ + +   E  +L +  T+L+  
Sbjct: 3005 -ETEKNGLQGQIGRLESQNESLIESKKDMKEQNDKLQAQMDEMRRENNSLRQNQTQLERT 3063

Query: 617  SL-LESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASK 675
            +  LE++  +L  +L+ ++ +   ++D+L    + +++++ +E + +  E+    L +  
Sbjct: 3064 NNGLENKVGNLTDQLNQVKNQLSALQDQLKS-KENENEKLRNEREKLANEKNSVELQSKD 3122

Query: 676  KELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISEL 735
            K+  ++   LK D E L   I  L ++K    NKLQ   Q N  L D++E+M  ++I+ L
Sbjct: 3123 KDAEII--KLKSDAEHLNDKINSLNDEK----NKLQ---QANDKLNDQIEQMK-QQINNL 3172

Query: 736  LAKINHEEQSKIQTQF---GIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRR 792
              +  + EQ K + Q     I+ K+++ +     +E E S+ ++ I RL+++I  + D+ 
Sbjct: 3173 TNENKNMEQEKAKNQEKIQNIEPKLKQLEEEKSKLEDENSQNENEIQRLKDTIKELSDKL 3232

Query: 793  YSLERKADQLGSYLQEKQKAYSEYTIQE-DELVNRLAVLMDHDRVVEKQLLEIEHENKEL 851
                 K+++    L++     ++  +++  E++N+L   + +     +QL + + +  E 
Sbjct: 3233 ----AKSEEDNKLLKQSSSGTTDKQVEDLQEMLNKLRDDLKNLNSENEQLKQQKDQLSEK 3288

Query: 852  --QKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKR 909
                 N     E QN Q+S   ++Q  N   +  N+   A  +  K +     L  + ++
Sbjct: 3289 LNNSNNDKTKAETQNEQLS-KQLEQLNNEKNQMFNKYKNAIQDKAKVEIAKETLAKDNEK 3347

Query: 910  ITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKN 969
            +  E ++L  QK     D + +          D   LN+         +QL  Q+ +  N
Sbjct: 3348 LASEKESL-QQKLDSANDEKNKLEQDKHKLEIDNTKLNDAKSHLENEKSQLAQQINDLNN 3406

Query: 970  NIENLNMNVEELNKMNLELI--DKHVQKQQTQSPDYTEQ---YINEINKLNALLKQKDEE 1024
             ++ L    EE NK+  E    +K ++  Q       +Q    + ++ ++   L+Q ++E
Sbjct: 3407 KLQKLE---EEKNKLEEEKAQNEKKLENSQQDGDKLGQQNQDLLKQLEEIKQKLQQTEQE 3463

Query: 1025 IIALNQKINNAQVSYMSM---VSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEEL 1081
              AL Q+ N  Q     +   + D E +      KL+ +E+E     K+L +++Q   E+
Sbjct: 3464 KSALEQQKNEIQNKLNEIEQQMKDSEKEKEDIKQKLQQVEQEKSETQKKLEEAEQQKNEI 3523

Query: 1082 QILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXX 1141
            Q  + + + + K L+  K   E  + +TE    +   E  S+    ++            
Sbjct: 3524 QNKLEQTEQEKKNLENEKAETEKRLQETEEAKKNLANEK-SEAERKLEEVQNEKAETERK 3582

Query: 1142 LKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKS 1201
            L   EE     E    + Q      E Q+  T+ + LE   TE    ++ N++  ++ + 
Sbjct: 3583 LNEAEEANKNLENEKNETQKKLEEAEQQKAETQKL-LE--QTEEAKKNLANEK--SEAER 3637

Query: 1202 KLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQL 1261
            KL++      NL +  +E    +    +++     +L +   A +  + +K E + +++ 
Sbjct: 3638 KLQETEEAKKNLANEKSEAERKLEEVQNEKAETERKLNEAEEANKNLENEKNETQKKLEE 3697

Query: 1262 SAFE-SKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQI 1320
            +  + ++ ++LL+       EE  K +  E+ +  + KLQ+ EE  +NL  + ++   ++
Sbjct: 3698 AEQQKAETQKLLEQT-----EEAKKNLANEK-SEAERKLQETEEAKKNLANEKSEAERKL 3751

Query: 1321 EILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKS 1380
            E    E+++EK A                 + + E Q   +  EQ      +   Q +++
Sbjct: 3752 E----EVQNEK-AETERKLNEAEEANKNLENEKNETQKKLEEAEQQKAETQKLLEQTEEA 3806

Query: 1381 SXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQK---THEYTITLTQRNDEFENV 1437
                         ++ + E    E    LE + S+I +K   T +  + L     E + +
Sbjct: 3807 KKNLENEKSETEKKLQETE----EAKKNLEQEKSDIQKKLDETKQQKVNLENEKAETQKL 3862

Query: 1438 RQQLVEYEKRIEDLTYEKESELAILRLKMHENANHY-ETMQKESEIERVKLIEELNVKIT 1496
             ++  E +K +E+   E E  L          AN   E  +K  E++  K   E  +   
Sbjct: 3863 LEETEEAKKNLENEKAETEKRLQETEEAKKNLANEKSEAERKLEEVQNEKAETERKLNEA 3922

Query: 1497 ESVSLN--KQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKI 1554
            E  + N   +  E  K LEE   +  E Q  LE  E     L +E +  +  ++ +    
Sbjct: 3923 EEANKNLENEKNETQKKLEEAEQQKAETQKLLEQTEEAKKNLENEKSETEKKLQETEEAK 3982

Query: 1555 QKHVSFASDTKQGRDEQLDNTMNKE 1579
            +      SD ++  DE     +N E
Sbjct: 3983 KNLEQEKSDIQKKLDETKQQKVNLE 4007



 Score =  173 bits (421), Expect = 3e-41
 Identities = 328/1571 (20%), Positives = 654/1571 (41%), Gaps = 160/1571 (10%)

Query: 143  DVTHLSNTIKE-KDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXX 201
            +V   +N +KE  DN +  LQ  +      I DLQ+K++++++ IE   KA         
Sbjct: 1935 NVDEENNEMKEGADNLIDALQQSVDEKNKQIDDLQQKLDDQNREIELL-KAKV-----EQ 1988

Query: 202  XXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLE 261
                      ED     T+  E     E   ++ K+RL + I     +++  ++ +  ++
Sbjct: 1989 IENINEEEDNEDIVVASTRDVELENVEEESPEEAKERLAEQISQLQDKLTEKKKNSLQMK 2048

Query: 262  AARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANM 321
             A      E SKL +E+EQ              L  +  E + E+    ++K S E  N 
Sbjct: 2049 QALASKDAEISKLNEEIEQIKSEKEDQDKELEKLNNELTE-ALEKLENGKKKSSQEQNNE 2107

Query: 322  TE--LTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPL-ISRKSGRNT 378
             E      IE L+     ++  N+ L+N+        K++ +  K    L  S +   N 
Sbjct: 2108 NEEDFVDDIEKLKEERENLKSENESLKNQAPENEGLKKSLENLKKSNDDLNKSNEDKENK 2167

Query: 379  ASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXX 438
              +++S  S+L SE    + + K    EI  L   + S+    +D      ++D      
Sbjct: 2168 IKELESEISKLKSEINELEQNNKDKDREIEILSSKVSSIENVNLD-----DDEDDITVVG 2222

Query: 439  XXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQ--EQLKQELNDEIKDV 496
                   +T+    + E +   E  +  +  TN  +   ++  +   + K +  ++ K +
Sbjct: 2223 TRDISVDETIPTDNETETKTEPETNTNTNENTNETNEENVSSQEGNNEEKNQSKEDKKKL 2282

Query: 497  NVKDLIEKLKSAEEQITQL---NDEIDAANKNMIKVKSNHKL--KLKQMQKTIDNFS--- 548
             ++ L + L S + ++  L   ND++ + N+ +   KSNH+L  K K++++ I+N +   
Sbjct: 2283 RIQQLKQLLASKQGEVDALKSQNDDLKSENETL--SKSNHELGTKTKELEEEIENINNNK 2340

Query: 549  --KVSD----SNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDS----GRMIESDV 598
              +V D    S+ E+V  T ++    +   + E  K  L+  L + ++     +  E ++
Sbjct: 2341 EGEVIDEKEASDVEVVCSTRDVDFEYENENDPETLKSLLKSKLSELENLQKENKAKEDEI 2400

Query: 599  YKKMIEM--------ENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDK------- 643
             K   E+          LAET  +  + + +   +L  E +  Q+  ++++         
Sbjct: 2401 TKLNEELAKSEDAKRRELAETAERLNNEINTLHDELQNEQNARQKLIEDLQSNNKEPEKD 2460

Query: 644  ----LADISQLQSDQVCSEIKSV-HLE-EQIDALSASKKEL-ALVIENLKLDKEQLYGTI 696
                  ++ + +SD++   ++ + H + E+I AL   + E     +++L+     L   +
Sbjct: 2461 DNGDFMNVLEKKSDEINKALEEILHRQNEEIKALRDREAEKNKQTVDDLQKQIAMLNNKL 2520

Query: 697  KDLENDKEDIMNK---LQNYIQEN-MDLTDKLEKMSAEKISELLAKI------NHEEQSK 746
            K  +    D + K    Q    E+  D   +  K   +K +E++AK+       +EE  K
Sbjct: 2521 KPSDQTDNDQLQKELMFQEIEGESPEDRNKRYLKAIEDKFNEIIAKLQESINNQNEELKK 2580

Query: 747  IQTQF-GIDA---KIQERDLYIENIESELSKYKS-RICRLEESIAVMEDRRYSLERKADQ 801
            ++ +  G+DA   ++ ++   +  I+    K K+ R   +EE+   ++D   +LE + D 
Sbjct: 2581 LRQKCDGVDAIELQLAQKKAELNEIKDNYEKEKAEREKEVEENNKKLKDTINALENRLDS 2640

Query: 802  LGSYLQEK--------QKAYSE---YTIQEDELVNRLAVLMDHDRVVEKQL-LEIEHENK 849
             G   + K        +KA  +     I +  L   L  L     V+E QL  E E+  +
Sbjct: 2641 QGEQTRSKINSAEQTARKAKEDADSAVIAQKSLQAELNNLKQKYAVLEDQLKTEKENHQQ 2700

Query: 850  ELQKKNQILLEENQNLQISL----SDMQQHYNALVEKANRTDLAESESTKYQTQLRDLES 905
            E Q+  + L EE+    + +      +++  N   + +   D  +    + + ++  LE 
Sbjct: 2701 EAQQLKE-LAEEDATPMVCIHVVGEKLKKLQNDNEKLSENNDNLQKNINELKDKINGLEK 2759

Query: 906  NLKRITHE-----HQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQL 960
              K+   E     HQ   +Q+K    +LE E N  ++    D    N++ EK  + +   
Sbjct: 2760 QYKQDAAELSNVHHQLGALQEK--ATNLENE-NKSLKEENEDLMNQNKQLEKEKQQLLAQ 2816

Query: 961  EAQLQEYKNNIENLNMNVEELN----------KMNLELIDKHVQKQQTQSPDYTEQ---Y 1007
             + L+E KNN E   MN ++ N          K+ LE + ++  + +T+  +  +Q    
Sbjct: 2817 NSNLEENKNNQEQSLMNRKKKNDDLLKQIDDLKLELEELKRNNSQNETKLQNANQQIEMM 2876

Query: 1008 INEINKLNALLKQKDEEIIALNQK---INNAQVSYMSMVSDYESKLAQFTTKLENMEEEM 1064
             ++IN     +K   +++  L  K   +N+ Q+   +    YE       +  + + +E 
Sbjct: 2877 KDQINNDKEQIKSAQDKLNDLQNKNNELNSNQIVLENQKKMYEGLYNDMKSSNDKLNDEN 2936

Query: 1065 QRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLT--FEMNIPKTEGMI--ISSTIEP 1120
            ++ + Q++D  + N E+  L  E      EL++ K       N P+ +  I  +   +  
Sbjct: 2937 RKKTDQIIDLTKQNAEVSALKLENQRLNSELEKLKSNQPVSSNDPELQKQIEELKKQLNN 2996

Query: 1121 MSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLET 1180
            +S++   ++            L+ Q  E  I+ +  ++EQ+ KL  ++ E   +   L  
Sbjct: 2997 LSNEKKQIETEKNGLQGQIGRLESQ-NESLIESKKDMKEQNDKLQAQMDEMRRENNSLRQ 3055

Query: 1181 LNTEL--TGHDVVNQ-----EQINQLKSKLEQL-------NTENDNLLSTVAELRSSISS 1226
              T+L  T + + N+     +Q+NQ+K++L  L         EN+ L +   +L +  +S
Sbjct: 3056 NQTQLERTNNGLENKVGNLTDQLNQVKNQLSALQDQLKSKENENEKLRNEREKLANEKNS 3115

Query: 1227 AVDQRGFEIAELWK-----QHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQE 1281
               Q   + AE+ K     +HL  +       +++L+        + EQ+   + + T E
Sbjct: 3116 VELQSKDKDAEIIKLKSDAEHLNDKINSLNDEKNKLQQANDKLNDQIEQMKQQINNLTNE 3175

Query: 1282 ETN----KIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIED--EKVAFX 1335
              N    K    E++ +++ KL+  EE    L+++ +   N+I+ L+  I++  +K+A  
Sbjct: 3176 NKNMEQEKAKNQEKIQNIEPKLKQLEEEKSKLEDENSQNENEIQRLKDTIKELSDKLAKS 3235

Query: 1336 XXXXXXXXXXXXXXXDLRTEN-QSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXR 1394
                           D + E+ Q         + N+N EN QLK+               
Sbjct: 3236 EEDNKLLKQSSSGTTDKQVEDLQEMLNKLRDDLKNLNSENEQLKQQKDQLSEKLNNSNND 3295

Query: 1395 VNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYE 1454
               AE +  +L+ QLE  ++E  Q  ++Y   + Q   + E  ++ L    K  E L  E
Sbjct: 3296 KTKAETQNEQLSKQLEQLNNEKNQMFNKYKNAI-QDKAKVEIAKETLA---KDNEKLASE 3351

Query: 1455 KESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELN---KA 1511
            KES    L    ++  N  E  + + EI+  KL +  +    E   L +Q+ +LN   + 
Sbjct: 3352 KESLQQKLD-SANDEKNKLEQDKHKLEIDNTKLNDAKSHLENEKSQLAQQINDLNNKLQK 3410

Query: 1512 LEEEVAKTNE----MQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQG 1567
            LEEE  K  E     +  LEN + +   L  +  +L   +     K+Q+     S  +Q 
Sbjct: 3411 LEEEKNKLEEEKAQNEKKLENSQQDGDKLGQQNQDLLKQLEEIKQKLQQTEQEKSALEQQ 3470

Query: 1568 RDEQLDNTMNK 1578
            ++E + N +N+
Sbjct: 3471 KNE-IQNKLNE 3480



 Score =  149 bits (361), Expect = 6e-34
 Identities = 303/1552 (19%), Positives = 631/1552 (40%), Gaps = 148/1552 (9%)

Query: 147  LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINE-KDQIIEAKNKATTXXXXXXXXXXX 205
            +   +  KD  +S L  +++ +++   D  +++ +  +++ EA  K              
Sbjct: 2047 MKQALASKDAEISKLNEEIEQIKSEKEDQDKELEKLNNELTEALEKLENGKKKSSQEQNN 2106

Query: 206  XXXXXXEDTKQQMTKMQENFIAMEAEWKD---EKQRLLKDIESKDVRISSLEEANKLLEA 262
                   D  +++ + +EN  +     K+   E + L K +E+       L ++N+  E 
Sbjct: 2107 ENEEDFVDDIEKLKEERENLKSENESLKNQAPENEGLKKSLENLKKSNDDLNKSNEDKEN 2166

Query: 263  ARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQ--SIEPSC--EEKTEIEEKGSLEI 318
               E+  E SKL  E+ +              L+ +  SIE     +++ +I   G+ +I
Sbjct: 2167 KIKELESEISKLKSEINELEQNNKDKDREIEILSSKVSSIENVNLDDDEDDITVVGTRDI 2226

Query: 319  A--------NMTELTKKIELLEHLNCQIRQTNKELENKLATMGT-ESKAVSSPSKKG--- 366
            +        N TE   + E   + N    +TN+E  N  +  G  E K  S   KK    
Sbjct: 2227 SVDETIPTDNETETKTEPETNTNTNENTNETNEE--NVSSQEGNNEEKNQSKEDKKKLRI 2284

Query: 367  ---SPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVD 423
                 L++ K G   A K ++   +  +ETL++   +   K +  +LE  I+++N +   
Sbjct: 2285 QQLKQLLASKQGEVDALKSQNDDLKSENETLSKSNHELGTKTK--ELEEEIENINNNKEG 2342

Query: 424  KEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQE 483
            +  VI EK+             D    + + E+        L    +  E++ +  K +E
Sbjct: 2343 E--VIDEKEASDVEVVCSTRDVDF---EYENENDPETLKSLLKSKLSELENLQKENKAKE 2397

Query: 484  QLKQELNDEI---KDVNVKDLIEKLKSAEEQITQLNDEI----DAANKNMIKVKSNHKLK 536
                +LN+E+   +D   ++L E  +    +I  L+DE+    +A  K +  ++SN+K  
Sbjct: 2398 DEITKLNEELAKSEDAKRRELAETAERLNNEINTLHDELQNEQNARQKLIEDLQSNNKEP 2457

Query: 537  LKQMQKTIDN-FSKVSDSNKEIVRLTEE-LHHLSQKVAELEEEKGNLQLHLVDYDSGRMI 594
             K       N   K SD   EI +  EE LH  ++++  L + +       VD D  + I
Sbjct: 2458 EKDDNGDFMNVLEKKSD---EINKALEEILHRQNEEIKALRDREAEKNKQTVD-DLQKQI 2513

Query: 595  ESDVYKKMIEMENLAETRLKAISLLESQKFDLVQE-----LHILQQKYDEVEDKLADISQ 649
               +  K+   +     +L+   + +  + +  ++     L  ++ K++E+  KL +   
Sbjct: 2514 AM-LNNKLKPSDQTDNDQLQKELMFQEIEGESPEDRNKRYLKAIEDKFNEIIAKLQESIN 2572

Query: 650  LQSDQVCSEIKSVHLEEQIDALSASKK-ELALVIENLKLDKEQLYGTIKDLENDKEDIMN 708
             Q++++    +     + I+   A KK EL  + +N + +K +    +++     +D +N
Sbjct: 2573 NQNEELKKLRQKCDGVDAIELQLAQKKAELNEIKDNYEKEKAEREKEVEENNKKLKDTIN 2632

Query: 709  KLQNYIQENMDLT-DKLE--KMSAEKISE-----------LLAKINH--------EEQSK 746
             L+N +    + T  K+   + +A K  E           L A++N+        E+Q K
Sbjct: 2633 ALENRLDSQGEQTRSKINSAEQTARKAKEDADSAVIAQKSLQAELNNLKQKYAVLEDQLK 2692

Query: 747  IQTQFGIDAKIQERDLYIENIESELSKYK--SRICRLEESIAVMEDRRYSLERKADQLGS 804
             + +       Q ++L  E+    +  +    ++ +L+     + +   +L++  ++L  
Sbjct: 2693 TEKENHQQEAQQLKELAEEDATPMVCIHVVGEKLKKLQNDNEKLSENNDNLQKNINELKD 2752

Query: 805  YLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQN 864
             +   +K Y +   +   + ++L  L +    +E +   ++ EN++L  +N+ L +E Q 
Sbjct: 2753 KINGLEKQYKQDAAELSNVHHQLGALQEKATNLENENKSLKEENEDLMNQNKQLEKEKQQ 2812

Query: 865  LQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKE 924
            L    S+++++ N   +          +  K    L+     LKR   +++T +    ++
Sbjct: 2813 LLAQNSNLEENKNNQEQSLMNRKKKNDDLLKQIDDLKLELEELKRNNSQNETKLQNANQQ 2872

Query: 925  IEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQ---LEAQLQEYKNNIENLNMNVEEL 981
            IE ++ + N   E     +  LN+   KN E  +    LE Q + Y+    ++  + ++L
Sbjct: 2873 IEMMKDQINNDKEQIKSAQDKLNDLQNKNNELNSNQIVLENQKKMYEGLYNDMKSSNDKL 2932

Query: 982  NKMNL----ELIDKHVQKQQTQSPDYTEQYIN-EINKL--NALLKQKDEE----IIALNQ 1030
            N  N     ++ID   Q  +  +     Q +N E+ KL  N  +   D E    I  L +
Sbjct: 2933 NDENRKKTDQIIDLTKQNAEVSALKLENQRLNSELEKLKSNQPVSSNDPELQKQIEELKK 2992

Query: 1031 KINN----------------AQVSYMSMVSD--YESK--LAQFTTKLENMEEEMQRVSKQ 1070
            ++NN                 Q+  +   ++   ESK  + +   KL+   +EM+R +  
Sbjct: 2993 QLNNLSNEKKQIETEKNGLQGQIGRLESQNESLIESKKDMKEQNDKLQAQMDEMRRENNS 3052

Query: 1071 LLDS----KQHNEELQILVREQDDQIKELKE--TKLTFEMNIPKTEGMIISSTIEPMSDD 1124
            L  +    ++ N  L+  V    DQ+ ++K   + L  ++   + E   + +  E ++++
Sbjct: 3053 LRQNQTQLERTNNGLENKVGNLTDQLNQVKNQLSALQDQLKSKENENEKLRNEREKLANE 3112

Query: 1125 ANNVDXXXXXXXXXXXXLKVQEE------EEFIQERSVLQEQSAKLNTELQECYTKIIQL 1178
             N+V+            LK   E           E++ LQ+ + KLN ++++   +I  L
Sbjct: 3113 KNSVELQSKDKDAEIIKLKSDAEHLNDKINSLNDEKNKLQQANDKLNDQIEQMKQQINNL 3172

Query: 1179 ETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNL-------LSTVAELRSSISSAVDQ- 1230
               N  +      NQE+I  ++ KL+QL  E   L        + +  L+ +I    D+ 
Sbjct: 3173 TNENKNMEQEKAKNQEKIQNIEPKLKQLEEEKSKLEDENSQNENEIQRLKDTIKELSDKL 3232

Query: 1231 -RGFEIAELWKQHLA----QREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNK 1285
             +  E  +L KQ  +    ++  D Q+  ++LR  L    S+ EQL       +++  N 
Sbjct: 3233 AKSEEDNKLLKQSSSGTTDKQVEDLQEMLNKLRDDLKNLNSENEQLKQQKDQLSEKLNNS 3292

Query: 1286 IVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXX 1345
                 +  +   +L  + E L N + +  +        ++++E  K              
Sbjct: 3293 NNDKTKAETQNEQLSKQLEQLNNEKNQMFNKYKNAIQDKAKVEIAKETLAKDNEKLASEK 3352

Query: 1346 XXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLEL 1405
                  L + N   K   EQ    +  +N +L  +             ++ND   K+ +L
Sbjct: 3353 ESLQQKLDSANDE-KNKLEQDKHKLEIDNTKLNDAKSHLENEKSQLAQQINDLNNKLQKL 3411

Query: 1406 THQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLK 1465
              +    + E  Q   +      Q  D+     Q L++  + I+    + E E + L  +
Sbjct: 3412 EEEKNKLEEEKAQNEKKLE-NSQQDGDKLGQQNQDLLKQLEEIKQKLQQTEQEKSALEQQ 3470

Query: 1466 MHE---NANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEM 1522
             +E     N  E   K+SE E+    E++  K+ +   + ++ +E  K LEE   + NE+
Sbjct: 3471 KNEIQNKLNEIEQQMKDSEKEK----EDIKQKLQQ---VEQEKSETQKKLEEAEQQKNEI 3523

Query: 1523 QTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDN 1574
            Q  LE  E E   L +E    +  ++  + + +K+++      + + E++ N
Sbjct: 3524 QNKLEQTEQEKKNLENEKAETEKRLQ-ETEEAKKNLANEKSEAERKLEEVQN 3574



 Score =  135 bits (327), Expect = 8e-30
 Identities = 260/1383 (18%), Positives = 584/1383 (42%), Gaps = 135/1383 (9%)

Query: 244  ESKDVRISSLEEANKLLEAARFEIS-LEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEP 302
            ES+D +  S EE  + +E  + ++  L++S   + +++                +QS++ 
Sbjct: 1903 ESEDNK--SPEELKREIENLKKQLEDLKNSGSQENVDEENNEMKEGADNLIDALQQSVDE 1960

Query: 303  SCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSP 362
              ++  ++++K       + +  ++IELL+    QI   N+E +N       E   V+S 
Sbjct: 1961 KNKQIDDLQQK-------LDDQNREIELLKAKVEQIENINEEEDN-------EDIVVAST 2006

Query: 363  SKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLV 422
                   +  +S      ++    SQL  +   +  +    K  +A  +  I  LN+++ 
Sbjct: 2007 RDVELENVEEESPEEAKERLAEQISQLQDKLTEKKKNSLQMKQALASKDAEISKLNEEI- 2065

Query: 423  DKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQ 482
              E + SEK+                + +L+   ++  +  +  +     +D+ ++ + +
Sbjct: 2066 --EQIKSEKEDQDKELEKLNNELTEALEKLENGKKKSSQEQNNENEEDFVDDIEKLKEER 2123

Query: 483  EQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQK 542
            E LK E N+ +K+   ++  E LK + E + + ND+++ +N++    K N   K+K+++ 
Sbjct: 2124 ENLKSE-NESLKNQAPEN--EGLKKSLENLKKSNDDLNKSNED----KEN---KIKELES 2173

Query: 543  TIDNF-SKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDV-YK 600
             I    S++++  +       E+  LS KV+ +E    N+ L   + D   +   D+   
Sbjct: 2174 EISKLKSEINELEQNNKDKDREIEILSSKVSSIE----NVNLDDDEDDITVVGTRDISVD 2229

Query: 601  KMIEMENLAETRLK-AISLLESQKFDLVQELHILQQK--YDEVEDKLADISQLQSDQVCS 657
            + I  +N  ET+ +   +   ++  +   E ++  Q+   +E      D  +L+  Q+  
Sbjct: 2230 ETIPTDNETETKTEPETNTNTNENTNETNEENVSSQEGNNEEKNQSKEDKKKLRIQQLKQ 2289

Query: 658  EIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQEN 717
             + S   + ++DAL +   +L    E L     +L    K+LE + E+I N  +  + + 
Sbjct: 2290 LLAS--KQGEVDALKSQNDDLKSENETLSKSNHELGTKTKELEEEIENINNNKEGEVIDE 2347

Query: 718  MDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSR 777
             + +D     S   +        +E ++  +T   + + ++ +   +EN++ E    +  
Sbjct: 2348 KEASDVEVVCSTRDVD-----FEYENENDPET---LKSLLKSKLSELENLQKENKAKEDE 2399

Query: 778  ICRLEESIAVMED-RRYSLERKADQLGS-------YLQEKQKAYSEY---------TIQE 820
            I +L E +A  ED +R  L   A++L +        LQ +Q A  +            ++
Sbjct: 2400 ITKLNEELAKSEDAKRRELAETAERLNNEINTLHDELQNEQNARQKLIEDLQSNNKEPEK 2459

Query: 821  DELVNRLAVLMDHDRVVEKQLLEIEH-ENKELQKKNQILLEENQNLQISLSDMQQHYNAL 879
            D+  + + VL      + K L EI H +N+E++       E+N+    ++ D+Q+    L
Sbjct: 2460 DDNGDFMNVLEKKSDEINKALEEILHRQNEEIKALRDREAEKNKQ---TVDDLQKQIAML 2516

Query: 880  VEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESA 939
              K   +D  +++  + +   +++E       ++     ++ K    ++  +    I + 
Sbjct: 2517 NNKLKPSDQTDNDQLQKELMFQEIEGESPEDRNKRYLKAIEDK--FNEIIAKLQESINNQ 2574

Query: 940  IRDKKVLNEKYE--KNIE-YVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQ 996
              + K L +K +    IE  + Q +A+L E K+N E      E+  + N + +   +   
Sbjct: 2575 NEELKKLRQKCDGVDAIELQLAQKKAELNEIKDNYEKEKAEREKEVEENNKKLKDTINAL 2634

Query: 997  QTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTK 1056
            + +     EQ  ++IN      ++  E+  A +  I  AQ S  + +++ + K A    +
Sbjct: 2635 ENRLDSQGEQTRSKINSAEQTARKAKED--ADSAVI--AQKSLQAELNNLKQKYAVLEDQ 2690

Query: 1057 LENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELK-------ETKLTFEMNIPKT 1109
            L+  +E  Q+ ++QL +  + +    + +    +++K+L+       E     + NI + 
Sbjct: 2691 LKTEKENHQQEAQQLKELAEEDATPMVCIHVVGEKLKKLQNDNEKLSENNDNLQKNINEL 2750

Query: 1110 EGMI--ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTE 1167
            +  I  +    +  + + +NV             L+  E +   +E   L  Q+ +L  E
Sbjct: 2751 KDKINGLEKQYKQDAAELSNVHHQLGALQEKATNLE-NENKSLKEENEDLMNQNKQLEKE 2809

Query: 1168 LQECYTKIIQLE---------TLNTELTGHDVVNQEQINQLKSKLEQL---NTENDNLLS 1215
             Q+   +   LE          +N +    D++  +QI+ LK +LE+L   N++N+  L 
Sbjct: 2810 KQQLLAQNSNLEENKNNQEQSLMNRKKKNDDLL--KQIDDLKLELEELKRNNSQNETKLQ 2867

Query: 1216 TVAELRSSISSAV--DQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLL- 1272
               +    +   +  D+   + A+     L  +  +    +  L  Q   +E  Y  +  
Sbjct: 2868 NANQQIEMMKDQINNDKEQIKSAQDKLNDLQNKNNELNSNQIVLENQKKMYEGLYNDMKS 2927

Query: 1273 --DSVQSSTQEETNKIVTM----EQVTSLQ---NKLQDKEEHLRNLQ---EKYADVINQI 1320
              D +    +++T++I+ +     +V++L+    +L  + E L++ Q       ++  QI
Sbjct: 2928 SNDKLNDENRKKTDQIIDLTKQNAEVSALKLENQRLNSELEKLKSNQPVSSNDPELQKQI 2987

Query: 1321 EILRSE---IEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQL 1377
            E L+ +   + +EK                      +  +S K M+EQ+   +  +  ++
Sbjct: 2988 EELKKQLNNLSNEKKQIETEKNGLQGQIGRLESQNESLIESKKDMKEQND-KLQAQMDEM 3046

Query: 1378 KKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENV 1437
            ++ +              N  E KV  LT QL    +++     +   +    N++  N 
Sbjct: 3047 RRENNSLRQNQTQLERTNNGLENKVGNLTDQLNQVKNQL-SALQDQLKSKENENEKLRNE 3105

Query: 1438 RQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITE 1497
            R++L   +  +E  + +K++E+    +K+  +A H          E+ KL ++ N K+ +
Sbjct: 3106 REKLANEKNSVELQSKDKDAEI----IKLKSDAEHLNDKINSLNDEKNKL-QQANDKLND 3160

Query: 1498 SVSLNKQ----VAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSK 1553
             +   KQ    +   NK +E+E AK  E    ++N E ++  L +E + L++    + ++
Sbjct: 3161 QIEQMKQQINNLTNENKNMEQEKAKNQE---KIQNIEPKLKQLEEEKSKLEDENSQNENE 3217

Query: 1554 IQK 1556
            IQ+
Sbjct: 3218 IQR 3220



 Score =  132 bits (319), Expect = 8e-29
 Identities = 248/1267 (19%), Positives = 508/1267 (40%), Gaps = 107/1267 (8%)

Query: 146  HLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXX 205
            +L N   E    L   +   K +E    + ++++ E +   EAK                
Sbjct: 3851 NLENEKAETQKLLEETEEAKKNLENEKAETEKRLQETE---EAKKNLANEKSEAERKLEE 3907

Query: 206  XXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSL----EEANKLLE 261
                  E T++++ + +E    +E E K+E Q+ L++ E +      L    EEA K LE
Sbjct: 3908 VQNEKAE-TERKLNEAEEANKNLENE-KNETQKKLEEAEQQKAETQKLLEQTEEAKKNLE 3965

Query: 262  AARFEIS-----LEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSL 316
              + E        E +K   E E+              +  ++ +   ++  E  E+   
Sbjct: 3966 NEKSETEKKLQETEEAKKNLEQEKSDIQKKLDETKQQKVNLENEKAETQKLLEETEEAKK 4025

Query: 317  EIAN-MTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLI--SRK 373
             + N   E  KK++  E     + Q   + E KL  +  E  A+ +   +    +  + K
Sbjct: 4026 NLENEKAETQKKLDEAEEAKKNLEQEKSDAEKKLEEVQNEKSALENEKNETQKKLEEAEK 4085

Query: 374  SGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDT 433
            +      +  +   QL     +   ++K    E +KL+  +  L   L D E  +++K+ 
Sbjct: 4086 AKDQIVEEKSAVERQLVESQKDSSENQKQQDEEKSKLQQQLSDLQNKLNDLEKKLADKEN 4145

Query: 434  XXXXXXXXXXGKDTLIAQLQ-----LEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQE 488
                           + QLQ     LE ++         +    +  N +      +K  
Sbjct: 4146 EKEQEKTQKDDLQKQLDQLQKDFDNLEREKQKLQDKNDSMKETIDSKNMLLDSFGTIKDH 4205

Query: 489  LND-EIKDVNVKDLIEKLKSAEEQITQLNDE----IDAANKNMIKVKSNHKLKLKQMQKT 543
            LND    +  ++D   KL+   ++ T  N+E    ID  N+ +  + +  K   ++++ T
Sbjct: 4206 LNDANNNNKKLQDENNKLRDDAQKATSKNNELQSIIDDLNRKLANLDAEKKATEEKLKNT 4265

Query: 544  IDNFSKVSDSNK---EIVRLTEELH-HLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVY 599
             D   +     K   + +R TE       +K+A+ EEEK  ++  L   ++ +    D  
Sbjct: 4266 EDKLKQAEAEKKATEDKLRETENAKKETEEKLAKTEEEKKQVEDKLAATEAAKKETEDKL 4325

Query: 600  KKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADIS--QLQSDQVCS 657
            K+  + +   E +L  +   E++K D+ Q     + K  + E++ A +   +  ++    
Sbjct: 4326 KQTEDEKKATEDKLANV---EAEKSDIEQAKKETEDKLKQTEEEKAAVEAEKKATEDKLH 4382

Query: 658  EIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQEN 717
            E +    E + D L  ++ E A V E  K + E     +K  E +K+   NKL+    E 
Sbjct: 4383 ETEEAKKETE-DKLKQTEDEKAAV-EQAKKETED---KLKQTEEEKKATENKLEESEAEK 4437

Query: 718  MDLTDKLEKM--SAEK----ISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESEL 771
             +L ++ E    S EK    +  LL+K+  E ++  + +  +++K+++ +   +  E +L
Sbjct: 4438 KELGERFESSRGSTEKQVSDLENLLSKLKDELKNIKEDKSQLESKLKQAEAEKKATEDKL 4497

Query: 772  SKYKSRICRLEES-------IAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDEL- 823
            +K +     LE++       +A +E+ + + E + + L     + QKA ++   ++++L 
Sbjct: 4498 AKTEVEKAALEQAKKETEDKLANVENEKKATETQKNDLAKEKTDLQKALAKLLKRQEQLD 4557

Query: 824  ------VNRLAVLMDHDRVVEKQLLEIEHENKELQKK-----NQILLEENQN------LQ 866
                    +   L    +  E++L   E E KE Q K     + +   E++       L+
Sbjct: 4558 AEKKALEEKANALESEKKATEEKLANAEKEKKETQDKLKQTEDNLAKSESEKKATEDKLK 4617

Query: 867  ISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIE 926
             + S+  Q   A  E  ++   AE+E    + +L+  E   K    + Q    +KK E E
Sbjct: 4618 QTESEKAQIEAAKKETEDKLQNAENEKKAAEEKLKQSEEQKKATEEKLQEAEAEKKAEQE 4677

Query: 927  DL-EIEFNTQ-----IESAIRD--------KKVLNEKYEKNIEYVTQLEAQLQEYKNNIE 972
             L  IE   Q      E  + D        K++L +  E   +   +L    Q+ + +  
Sbjct: 4678 KLANIEAEKQQLGNASEKQVSDLSGEISKLKQLLKQLAEAKKKADEELAKSKQDKEQSDN 4737

Query: 973  NLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKI 1032
            + +   E+LN +  +L D  ++K + +S    +   + +NKL    KQKD+EI  L  K 
Sbjct: 4738 DKSKLQEDLNNLKKQLED--LEKAKKESDSNNKLLADSVNKLKEQNKQKDDEIKNLTDKA 4795

Query: 1033 NNAQVSYMS----MVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQ 1088
            N  Q    +     V     +L++   KLEN ++ ++     +  + + ++   +   E+
Sbjct: 4796 NQPQDINNNPDFVKVKKAFLQLSKTNEKLENEKKALEGAVNSIYSTMKKDDSAPL--DEK 4853

Query: 1089 DDQIKELKETKLTFEMNI-PKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEE 1147
               +++ +  K   + N   K +          M+D  N++             +K +E+
Sbjct: 4854 ATPMQQAERAKELIQNNSGKKVDPEFFEKLTNEMNDLFNSICKVFRTNSPITFDIKKEED 4913

Query: 1148 EEFIQERS-VLQEQSAKLNTELQECYTK-IIQLETLNTELTGHDVVNQEQINQLKSKLEQ 1205
               I + S VL++      T+L     K   Q+  L  +     + N+E      + +  
Sbjct: 4914 IATIGQNSIVLRKVMKSYLTQLSNDIIKDKQQISDLKHDKNSLQMENEEIKATASANMSS 4973

Query: 1206 LNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFE 1265
             +  ND L+ +  ++ + +   + +   E  E+      Q  ++    E  L   +  F 
Sbjct: 4974 KDINNDKLIKSYKKVYARMKQ-LQEAEREAKEILLLACPQLRSEI-NIEEGLVTFVKNFV 5031

Query: 1266 SKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRS 1325
            +K+  L+ S+ ++ Q E   I   ++++ LQ+ + DK      + +KY  ++N+  +  +
Sbjct: 5032 TKFPVLIASL-AADQIERPFISLDQRISKLQSSV-DK------IIQKYEALVNRYSLAST 5083

Query: 1326 EIEDEKV 1332
                E V
Sbjct: 5084 ATNPEAV 5090



 Score =  125 bits (301), Expect = 1e-26
 Identities = 233/1129 (20%), Positives = 488/1129 (43%), Gaps = 126/1129 (11%)

Query: 469  GTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQ--LNDEIDAANKNM 526
            G   +  +E+ K  E+LK+E N  +K  N  +L ++L    +QI +  +N+   +     
Sbjct: 1849 GKEHKSPSELLKENEELKKE-NQRLKKENA-ELKKRLGIPVDQIIEGIMNESTASDESED 1906

Query: 527  IKVKSNHKLKLKQMQKTIDNFSK------VSDSNKEIVRLTEEL-HHLSQKVAELEEEKG 579
             K     K +++ ++K +++         V + N E+    + L   L Q V E  ++  
Sbjct: 1907 NKSPEELKREIENLKKQLEDLKNSGSQENVDEENNEMKEGADNLIDALQQSVDEKNKQID 1966

Query: 580  NLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDE 639
            +LQ  L D +  R IE  +  K+ ++EN+ E       ++ S + D+  E ++ ++  +E
Sbjct: 1967 DLQQKLDDQN--REIEL-LKAKVEQIENINEEEDNEDIVVASTR-DVELE-NVEEESPEE 2021

Query: 640  VEDKLAD-ISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKD 698
             +++LA+ ISQLQ      +  S+ +++ + +  A   +L   IE +K +KE     ++ 
Sbjct: 2022 AKERLAEQISQLQDKLTEKKKNSLQMKQALASKDAEISKLNEEIEQIKSEKEDQDKELEK 2081

Query: 699  LENDKEDIMNKLQN------YIQEN---MDLTDKLEKMSAEKISELLAKINHEEQSKIQT 749
            L N+  + + KL+N        Q N    D  D +EK+  E+  E L   N   +++   
Sbjct: 2082 LNNELTEALEKLENGKKKSSQEQNNENEEDFVDDIEKLKEER--ENLKSENESLKNQAPE 2139

Query: 750  QFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLE---RKADQLGSYL 806
              G+   ++      +++       +++I  LE  I+ ++     LE   +  D+    L
Sbjct: 2140 NEGLKKSLENLKKSNDDLNKSNEDKENKIKELESEISKLKSEINELEQNNKDKDREIEIL 2199

Query: 807  QEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQ 866
              K  +     + +DE  + + V+   D  V++ +      + E + K +   E N N  
Sbjct: 2200 SSKVSSIENVNLDDDE--DDITVVGTRDISVDETI----PTDNETETKTE--PETNTNTN 2251

Query: 867  ISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIE 926
             + ++  +  N   ++ N  +  +S+  K + +++ L+            L+  K+ E++
Sbjct: 2252 ENTNETNEE-NVSSQEGNNEEKNQSKEDKKKLRIQQLKQ-----------LLASKQGEVD 2299

Query: 927  DLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNL 986
             L        +S   D K  NE   K+     +L  + +E +  IEN+N N E       
Sbjct: 2300 AL--------KSQNDDLKSENETLSKSNH---ELGTKTKELEEEIENINNNKEGEVIDEK 2348

Query: 987  ELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDY 1046
            E  D  V    T+  D+  +  N+   L +LLK K  E+  L QK N A+   ++ +++ 
Sbjct: 2349 EASDVEV-VCSTRDVDFEYENENDPETLKSLLKSKLSELENL-QKENKAKEDEITKLNEE 2406

Query: 1047 ESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNI 1106
             +K      K   + E  +R++ ++  +  H+E    L  EQ+ + K +++ + +     
Sbjct: 2407 LAKSED--AKRRELAETAERLNNEI--NTLHDE----LQNEQNARQKLIEDLQ-SNNKEP 2457

Query: 1107 PKTEGMIISSTIEPMSDDANN-VDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLN 1165
             K +     + +E  SD+ N  ++            L+ +E E+  Q    LQ+Q A LN
Sbjct: 2458 EKDDNGDFMNVLEKKSDEINKALEEILHRQNEEIKALRDREAEKNKQTVDDLQKQIAMLN 2517

Query: 1166 TELQ---ECYTKIIQLETLNTELTGHDVVN---------QEQINQLKSKL-EQLNTENDN 1212
             +L+   +     +Q E +  E+ G    +         +++ N++ +KL E +N +N+ 
Sbjct: 2518 NKLKPSDQTDNDQLQKELMFQEIEGESPEDRNKRYLKAIEDKFNEIIAKLQESINNQNEE 2577

Query: 1213 L--LSTVAELRSSISSAVDQRGFEIAEL---WKQHLAQREADFQKTEHELRVQLSAFESK 1267
            L  L    +   +I   + Q+  E+ E+   +++  A+RE + ++   +L+  ++A E++
Sbjct: 2578 LKKLRQKCDGVDAIELQLAQKKAELNEIKDNYEKEKAEREKEVEENNKKLKDTINALENR 2637

Query: 1268 YEQLLDSVQS--STQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRS 1325
             +   +  +S  ++ E+T +    E   S     +  +  L NL++KYA + +Q++  + 
Sbjct: 2638 LDSQGEQTRSKINSAEQTAR-KAKEDADSAVIAQKSLQAELNNLKQKYAVLEDQLKTEKE 2696

Query: 1326 EIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXX 1385
              + E                     +    +  K++Q  +   ++E N  L+K+     
Sbjct: 2697 NHQQE----AQQLKELAEEDATPMVCIHVVGEKLKKLQNDN-EKLSENNDNLQKN----- 2746

Query: 1386 XXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYE 1445
                     +N+ + K+  L  Q + +D+      H     L ++    EN  + L E  
Sbjct: 2747 ---------INELKDKINGLEKQYK-QDAAELSNVHHQLGALQEKATNLENENKSLKEEN 2796

Query: 1446 KRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQV 1505
            + + +   + E E   L L  + N    +  Q++S + R K          ++  L KQ+
Sbjct: 2797 EDLMNQNKQLEKEKQQL-LAQNSNLEENKNNQEQSLMNRKK----------KNDDLLKQI 2845

Query: 1506 AELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKI 1554
             +L   LEE     ++ +T L+N   +I  + D+I N +  ++++  K+
Sbjct: 2846 DDLKLELEELKRNNSQNETKLQNANQQIEMMKDQINNDKEQIKSAQDKL 2894



 Score =  120 bits (289), Expect = 3e-25
 Identities = 283/1336 (21%), Positives = 555/1336 (41%), Gaps = 144/1336 (10%)

Query: 261  EAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIAN 320
            E  RF+I    S+  QEL +              +     +     + +IEEK    +  
Sbjct: 32   EIDRFDIDSISSRPLQELAELAYDKNEKISSK--VVNSMADQFAVYERQIEEKTETILQQ 89

Query: 321  MTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTAS 380
              E+       ++ + + +    ELE + A     S+ ++S      PL  R  G +   
Sbjct: 90   NNEIDSL--RAKYNDARAKSAAYELELQKAKQSLISRTINSNIH---PL--RSIGHDLED 142

Query: 381  KMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXX 440
            + +S    +SS     D + +   +E+++L+    S N +LV     + +  T       
Sbjct: 143  EKESLSDSISSTISIYDENLESLNDELSRLKQ--NSQNSELVK----VLDNLTRTTDYVV 196

Query: 441  XXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKD 500
                 + L      + Q      + + + T    +N  A++QE    +   +I     K+
Sbjct: 197  NLENNENLERYTTYDAQLRAISQAALRLSTKVNSLN--AELQELKHSQSEMQIIVSQYKE 254

Query: 501  LIEKLK---SAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEI 557
            ++ K+       E++  +ND  D  +KN +      K    ++Q+  DN  K   +NKE+
Sbjct: 255  VVPKISFHIETIEKLVSINDT-DEDDKNPLIFPQRLKRIRSEVQRLFDNNEK---TNKEL 310

Query: 558  VRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAIS 617
             +L E+L        EL E   N Q         R  E +  +  +E +N    +LKA  
Sbjct: 311  QKLKEQL--------ELYENMKNGQSM-----KERQAELESLRLELEKKNAELEQLKA-R 356

Query: 618  LLESQKFDLVQELHILQQKYDEVEDKLADI-SQLQSDQVCS---EIKSVHLEEQIDALSA 673
                Q   L+ E+  ++ +   +++K+AD  SQ+++  +     +      +E I+ L  
Sbjct: 357  YQSKQDPQLLAEIERIENEVQNLKNKIADRESQIKALNLLIAQYQTDDEDKKEIIENLEK 416

Query: 674  SKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNK-LQNYIQENMDLTD----KLEKMS 728
              K+L   IE+   + E L   I  +E   ED  ++ +      ++DL D    + E++S
Sbjct: 417  EIKDLKKQIEDKDKEIEVLKAKIAKIEEIPEDEEDEDIVVAGTRDVDLGDFNEEEAEQVS 476

Query: 729  AE-KISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAV 787
             E ++ +L  K++ ++++ +Q +  + +K    D  IE +  ++ + K R  + E++I  
Sbjct: 477  LEDQVKQLKEKLDDKKKNGVQMKQALASK----DAEIEKLNEQIQELKDRNDKQEQNIEE 532

Query: 788  MEDRRYSLERKADQLGSYLQEKQ---KAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEI 844
            +  +   L+   D+    + E Q   K  ++   +  +L N      D ++  E +  E 
Sbjct: 533  LNTKNSDLQNSNDEYKKLIDELQNQLKDLAKNKAESSDLNNSENTKQDSEKA-EDENAET 591

Query: 845  EHENKELQKKNQILLEENQNLQISLSDMQQHYNAL----VEKANRTDLAESESTKYQTQL 900
            +  NKELQ+++  L  EN+ L+ SL ++++  + L     +K N+    ESE +K ++++
Sbjct: 592  K-SNKELQEESDKLKSENEGLKKSLENLKKSNDDLNKSNEDKENKIKELESEISKLKSEI 650

Query: 901  RDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQL 960
             +LE N K    E + ++  K   IE++ ++ +    + +  + +     ++ I    + 
Sbjct: 651  NELEQNNKDKDREIE-ILSSKVSSIENVNLDDDEDDITVVGTRDI---SVDETIPTDNET 706

Query: 961  EAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQ 1020
            E + +   N   N N N  E N+ N+   + +  +++ QS +  ++    I +L  LL  
Sbjct: 707  ETKTEPETNT--NTNENTNETNEENVSSQEGN-NEEKNQSKEDKKKL--RIQQLKQLLAS 761

Query: 1021 KDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSK----QLLDSKQ 1076
            K  E+ AL  + N+   S    +S    +L    TK + +EEE++ ++     +++D K+
Sbjct: 762  KQGEVDALKSQ-NDDLKSENETLSKSNHELE---TKNKELEEEIENINNNKEGEVIDEKE 817

Query: 1077 HNE-ELQILVREQD---------DQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDAN 1126
             ++ E+    R+ D         + +K L ++KL+   N+ K E   +   IE + ++  
Sbjct: 818  ASDVEVVCSTRDVDFEYENENDPETLKSLLKSKLSELENLQK-ENTDLMKQIEELKNENE 876

Query: 1127 NVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELT 1186
            N+             LK   E E +Q  +    QS     EL     +I QLE+L  EL 
Sbjct: 877  NLKRELENLKLENESLK--RENERLQLTADQSPQSKDKMIELLA--NQINQLESLVPELQ 932

Query: 1187 GHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQR 1246
                    +I +LK + +Q+  EN+ L     +L+ S S+              + + Q 
Sbjct: 933  Q----KTNEIEELKKENKQIKEENEKLKKENEDLKKSGSNKS-----------SEEINQE 977

Query: 1247 EADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHL 1306
            E D +K   +L+  L   +   E    S      EE  K V  E +        D +EH 
Sbjct: 978  EEDLKKQIEDLKKALGYPQDGKEHKTPSELIEENEELKKKV--EDLEKESGYPSDNKEH- 1034

Query: 1307 RNLQEKYADVINQIEILRSEIEDEKVAF----XXXXXXXXXXXXXXXXDLRTENQSYKQ- 1361
                +  ++++ + E L+ +++D + A                     +L+ +N + K+ 
Sbjct: 1035 ----KSPSELLKENEELKKKVDDLEKALGYPEDGKDHKSPSELIKENEELKKQNDALKRA 1090

Query: 1362 -------MQEQSILNINEENAQLKKS-SXXXXXXXXXXXXRVNDAEAKVLELTHQLELKD 1413
                      +S   + +EN +LKK  +            + +   +++L    +L+ K 
Sbjct: 1091 LGYPEDGKDHKSPSELIQENEELKKKVADLEKALGYPADGQEHKTPSELLRENEELK-KK 1149

Query: 1414 SEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYE-------KESELAILRLKM 1466
              I   T   T +  + N   E +R +  + +K+IEDL          KE +     +K 
Sbjct: 1150 LGISDST---TPSDNEDNKSPEELRSENKDLKKQIEDLKRALGYPEDGKEHKTPSELIKE 1206

Query: 1467 HENANHYETMQKES--EIERVKLIEELNVKITESVSLNKQVAELNKALE-EEVAKTNEMQ 1523
            +E         K++    E  K  +  +  I E+  L K+V +L KAL   E  K ++  
Sbjct: 1207 NEELKKQNDSLKKALGYSEDGKDHKSPSELIKENEDLKKKVEDLEKALGFPEDGKEHKTP 1266

Query: 1524 TAL--ENQEIEIVTLN 1537
            + L  EN+E++  T N
Sbjct: 1267 SELIKENEELKEETEN 1282



 Score =  100 bits (240), Expect = 3e-19
 Identities = 178/898 (19%), Positives = 380/898 (42%), Gaps = 74/898 (8%)

Query: 696  IKDLENDKEDIMNKLQNYIQENMDLT-DKLEKMSAEKISELL-------AKINHEEQSKI 747
            + + E D+ DI +     +QE  +L  DK EK+S++ ++ +         +I  + ++ +
Sbjct: 28   LNEEEIDRFDIDSISSRPLQELAELAYDKNEKISSKVVNSMADQFAVYERQIEEKTETIL 87

Query: 748  QTQFGID---AKIQERDLYIENIESELSKYK-SRICR-LEESIAVMEDRRYSLERKADQL 802
            Q    ID   AK  +        E EL K K S I R +  +I  +    + LE + + L
Sbjct: 88   QQNNEIDSLRAKYNDARAKSAAYELELQKAKQSLISRTINSNIHPLRSIGHDLEDEKESL 147

Query: 803  GSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEEN 862
               +      Y E     ++ ++RL     +  +V+         +  +  +N   LE  
Sbjct: 148  SDSISSTISIYDENLESLNDELSRLKQNSQNSELVKVLDNLTRTTDYVVNLENNENLERY 207

Query: 863  QNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLI--VQ 920
                  L  + Q    L  K N  +    E    Q++++ + S  K +  +    I  ++
Sbjct: 208  TTYDAQLRAISQAALRLSTKVNSLNAELQELKHSQSEMQIIVSQYKEVVPKISFHIETIE 267

Query: 921  KKKEIEDLEIEFNTQIESAIRDKKVLNE------KYEKNIEYVTQLEAQLQEYKN--NIE 972
            K   I D + +    +    R K++ +E        EK  + + +L+ QL+ Y+N  N +
Sbjct: 268  KLVSINDTDEDDKNPLIFPQRLKRIRSEVQRLFDNNEKTNKELQKLKEQLELYENMKNGQ 327

Query: 973  NLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKI 1032
            ++     EL  + LEL  K+ + +Q ++   ++Q      +L A +++ + E+  L  KI
Sbjct: 328  SMKERQAELESLRLELEKKNAELEQLKARYQSKQD----PQLLAEIERIENEVQNLKNKI 383

Query: 1033 NNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQI 1092
             + +    S +      +AQ+ T  E+ +E ++ + K++ D K+  E+     ++++ ++
Sbjct: 384  ADRE----SQIKALNLLIAQYQTDDEDKKEIIENLEKEIKDLKKQIED-----KDKEIEV 434

Query: 1093 KELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQ---EEEE 1149
             + K  K+       + E ++++ T +    D N  +            LK +   +++ 
Sbjct: 435  LKAKIAKIEEIPEDEEDEDIVVAGTRDVDLGDFNEEEAEQVSLEDQVKQLKEKLDDKKKN 494

Query: 1150 FIQERSVLQEQSA---KLNTELQECYTK-------IIQLETLNTELTGHDVVNQEQINQL 1199
             +Q +  L  + A   KLN ++QE   +       I +L T N++L   +   ++ I++L
Sbjct: 495  GVQMKQALASKDAEIEKLNEQIQELKDRNDKQEQNIEELNTKNSDLQNSNDEYKKLIDEL 554

Query: 1200 KSKLEQL--NTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHEL 1257
            +++L+ L  N    + L+     +     A D+     AE       Q E+D  K+E+E 
Sbjct: 555  QNQLKDLAKNKAESSDLNNSENTKQDSEKAEDEN----AETKSNKELQEESDKLKSENE- 609

Query: 1258 RVQLSAFESKYEQLLDSVQSSTQEETNKIVTME-QVTSLQNKLQDKEEHLRNLQEKYADV 1316
               L       ++  D +  S +++ NKI  +E +++ L++++ + E++ ++   +   +
Sbjct: 610  --GLKKSLENLKKSNDDLNKSNEDKENKIKELESEISKLKSEINELEQNNKDKDREIEIL 667

Query: 1317 INQIEILRS-EIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENA 1375
             +++  + +  ++D++                   D  TE ++  +    +  N NE N 
Sbjct: 668  SSKVSSIENVNLDDDEDDITVVGTRDISVDETIPTDNETETKTEPETNTNTNENTNETNE 727

Query: 1376 QLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQ-KTHEYTI-----TLTQ 1429
            +    S            + +  + ++ +L   L  K  E+   K+    +     TL++
Sbjct: 728  E--NVSSQEGNNEEKNQSKEDKKKLRIQQLKQLLASKQGEVDALKSQNDDLKSENETLSK 785

Query: 1430 RNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHEN---ANHYETMQKESEIERVK 1486
             N E E   ++L   E+ IE++   KE E+   +         +      + E+E +   
Sbjct: 786  SNHELETKNKEL---EEEIENINNNKEGEVIDEKEASDVEVVCSTRDVDFEYENENDPET 842

Query: 1487 LIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQ 1544
            L   L  K++E  +L K+  +L K +EE   +   ++  LEN ++E  +L  E   LQ
Sbjct: 843  LKSLLKSKLSELENLQKENTDLMKQIEELKNENENLKRELENLKLENESLKRENERLQ 900



 Score = 92.7 bits (220), Expect = 8e-17
 Identities = 237/1200 (19%), Positives = 480/1200 (40%), Gaps = 103/1200 (8%)

Query: 168  METTILDLQEKINEKD---QIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQEN 224
            +E  I DL+++I +KD   ++++AK                      +       + +  
Sbjct: 414  LEKEIKDLKKQIEDKDKEIEVLKAKIAKIEEIPEDEEDEDIVVAGTRDVDLGDFNEEEAE 473

Query: 225  FIAMEAEWKDEKQRL----LKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQ 280
             +++E + K  K++L       ++ K    S   E  KL E  + E+   + K  Q +E+
Sbjct: 474  QVSLEDQVKQLKEKLDDKKKNGVQMKQALASKDAEIEKLNEQIQ-ELKDRNDKQEQNIEE 532

Query: 281  XXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKK-IELLEHLNCQIR 339
                            K   E   + K   + K      N +E TK+  E  E  N + +
Sbjct: 533  LNTKNSDLQNSNDEYKKLIDELQNQLKDLAKNKAESSDLNNSENTKQDSEKAEDENAETK 592

Query: 340  QTNKELENKLATMGTES----KAVSSPSKKGSPL-ISRKSGRNTASKMKSPWSQLSSETL 394
             +NKEL+ +   + +E+    K++ +  K    L  S +   N   +++S  S+L SE  
Sbjct: 593  -SNKELQEESDKLKSENEGLKKSLENLKKSNDDLNKSNEDKENKIKELESEISKLKSEIN 651

Query: 395  NQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQL 454
              + + K    EI  L   + S+    +D      ++D             +T+    + 
Sbjct: 652  ELEQNNKDKDREIEILSSKVSSIENVNLD-----DDEDDITVVGTRDISVDETIPTDNET 706

Query: 455  EHQQHMEGPSLIHVGTNTEDVNEIAKVQ--EQLKQELNDEIKDVNVKDLIEKLKSAEEQI 512
            E +   E  +  +  TN  +   ++  +   + K +  ++ K + ++ L + L S + ++
Sbjct: 707  ETKTEPETNTNTNENTNETNEENVSSQEGNNEEKNQSKEDKKKLRIQQLKQLLASKQGEV 766

Query: 513  TQL---NDEIDAANKNMIKVKSNHKL--KLKQMQKTIDNFSKVSDSNKEIVRLTEELHHL 567
              L   ND++ + N+ +   KSNH+L  K K++++ I+N     ++NKE     E +   
Sbjct: 767  DALKSQNDDLKSENETL--SKSNHELETKNKELEEEIENI----NNNKE----GEVIDEK 816

Query: 568  SQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETR---LKAISLLESQKF 624
                 E+     ++     + +    ++S +  K+ E+ENL +     +K I  L+++  
Sbjct: 817  EASDVEVVCSTRDVDFEYENENDPETLKSLLKSKLSELENLQKENTDLMKQIEELKNENE 876

Query: 625  DLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIEN 684
            +L +EL  L+ + + ++ +   + QL +DQ          ++ I+ L+    +L    E+
Sbjct: 877  NLKRELENLKLENESLKRENERL-QLTADQ-----SPQSKDKMIELLANQINQL----ES 926

Query: 685  LKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQ 744
            L  + +Q    I++L+ + + I  + +   +EN DL       S+E+I++    +  + +
Sbjct: 927  LVPELQQKTNEIEELKKENKQIKEENEKLKKENEDLKKSGSNKSSEEINQEEEDLKKQIE 986

Query: 745  SKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGS 804
              ++   G     +E     E IE E  + K ++  LE+      D +   E K+     
Sbjct: 987  D-LKKALGYPQDGKEHKTPSELIE-ENEELKKKVEDLEKESGYPSDNK---EHKSP---- 1037

Query: 805  YLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQIL-----L 859
               E  K   E   + D+L   L      D    K   E+  EN+EL+K+N  L      
Sbjct: 1038 --SELLKENEELKKKVDDLEKALG--YPEDGKDHKSPSELIKENEELKKQNDALKRALGY 1093

Query: 860  EENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIV 919
             E+     S S++ Q    L +K    DL ++       Q     S L R   E     +
Sbjct: 1094 PEDGKDHKSPSELIQENEELKKKV--ADLEKALGYPADGQEHKTPSELLRENEE-----L 1146

Query: 920  QKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQ---LEAQLQEYKNNIENLNM 976
            +KK  I D     + +   +  + +  N+  +K IE + +        +E+K   E +  
Sbjct: 1147 KKKLGISDSTTPSDNEDNKSPEELRSENKDLKKQIEDLKRALGYPEDGKEHKTPSELIKE 1206

Query: 977  NVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEI-IALNQKINNA 1035
            N EEL K N  L  K          D+     +E+ K N  LK+K E++  AL    +  
Sbjct: 1207 N-EELKKQNDSL--KKALGYSEDGKDHKSP--SELIKENEDLKKKVEDLEKALGFPEDGK 1261

Query: 1036 QVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQIL-----VREQDD 1090
            +    S +     +L + T  ++   E+++R      D K+H    +++     +++Q++
Sbjct: 1262 EHKTPSELIKENEELKEETENIKKQIEDLKRALGYPEDGKEHKTPSELINENEELKKQNE 1321

Query: 1091 QIKELKETKLTFEMNIPKTEGMIISSTIEPMSDD-ANNVDXXXXXXXXXXXXLKVQEEEE 1149
             +K  K+  ++ E +  K++       I+  + +    ++             + +   E
Sbjct: 1322 NLK--KKLGISGESSTDKSDSNKTPEEIKQENGELKKQIEDLKKALGYPEDGKEHKSPSE 1379

Query: 1150 FIQERSVLQEQSAKLNTEL-----QECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLE 1204
             I+E   L++Q+  L   L      + +    +L   N EL     ++ E   +     E
Sbjct: 1380 LIKENEELKKQNDDLKRALGYPEDGKDHKTPSELIKENEELKKKLGISGESSTEESKSYE 1439

Query: 1205 QLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAF 1264
            +L    ++L   V +L  ++    D +  +        L +   + +K   +L+  L   
Sbjct: 1440 ELKDLINDLKKKVEDLEKALGYPSDGKDHKS----PSELLKENDELKKQNDDLKKALGYP 1495

Query: 1265 ESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILR 1324
            E   E    S      EE  K + + + +S  +K  +K      L+ +  ++  QIE L+
Sbjct: 1496 EDGKEHKSPSELIKENEELKKKLGLSEESSTDSKADNKSP--EELKNENNELKKQIEALK 1553



 Score = 91.1 bits (216), Expect = 2e-16
 Identities = 284/1387 (20%), Positives = 562/1387 (40%), Gaps = 137/1387 (9%)

Query: 223  ENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXX 282
            E  +++    +D+K  L+     K +R     E  +L +    + + E  KL ++LE   
Sbjct: 267  EKLVSINDTDEDDKNPLIFPQRLKRIR----SEVQRLFDNNE-KTNKELQKLKEQLELYE 321

Query: 283  XXXXXXXXXXXXLAKQSIEPSCEEKT-EIEE-KGSLEIANMTELTKKIELLEHLNCQIRQ 340
                           +S+    E+K  E+E+ K   +     +L  +IE +E+       
Sbjct: 322  NMKNGQSMKERQAELESLRLELEKKNAELEQLKARYQSKQDPQLLAEIERIEN------- 374

Query: 341  TNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDK 400
              + L+NK+A   ++ KA++    +       +  +     ++     L  +  ++D + 
Sbjct: 375  EVQNLKNKIADRESQIKALNLLIAQYQT--DDEDKKEIIENLEKEIKDLKKQIEDKDKEI 432

Query: 401  KINKNEIAKLEMVIQSLNKDLVDKEYVIS-EKDTXXXXXXXXXXGKDTL---IAQLQLEH 456
            ++ K +IAK+E     + +D  D++ V++  +D            + +L   + QL+ + 
Sbjct: 433  EVLKAKIAKIE----EIPEDEEDEDIVVAGTRDVDLGDFNEEEAEQVSLEDQVKQLKEKL 488

Query: 457  QQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELND--EIKDVNVKDLIEK---LKSAEEQ 511
                +    +     ++D  EI K+ EQ+ QEL D  + ++ N+++L  K   L+++ ++
Sbjct: 489  DDKKKNGVQMKQALASKDA-EIEKLNEQI-QELKDRNDKQEQNIEELNTKNSDLQNSNDE 546

Query: 512  ITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKV 571
              +L DE+    K++ K K+     L   + T  +  K  D N E  +  +EL   S K+
Sbjct: 547  YKKLIDELQNQLKDLAKNKAESS-DLNNSENTKQDSEKAEDENAE-TKSNKELQEESDKL 604

Query: 572  -AELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQEL 630
             +E E  K +L+      D       D   K+ E+E+        I+ LE    D  +E+
Sbjct: 605  KSENEGLKKSLENLKKSNDDLNKSNEDKENKIKELESEISKLKSEINELEQNNKDKDREI 664

Query: 631  HILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKE 690
             IL  K   +E+   ++   + D      + + ++E I   + ++          K + E
Sbjct: 665  EILSSKVSSIEN--VNLDDDEDDITVVGTRDISVDETIPTDNETET---------KTEPE 713

Query: 691  QLYGTIKDL-ENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQT 749
                T ++  E ++E++ ++  N  ++N    DK +K+  +++ +LLA     E   +++
Sbjct: 714  TNTNTNENTNETNEENVSSQEGNNEEKNQSKEDK-KKLRIQQLKQLLAS-KQGEVDALKS 771

Query: 750  QFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSL---ERKADQLGSYL 806
            Q   D K +   L   N E E +K K     LEE I  + + +      E++A  +    
Sbjct: 772  Q-NDDLKSENETLSKSNHELE-TKNKE----LEEEIENINNNKEGEVIDEKEASDVEVVC 825

Query: 807  QEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQ 866
              +   + EY  + D     L  L+        +L  ++ EN +L K+ + L  EN+NL+
Sbjct: 826  STRDVDF-EYENENDP--ETLKSLLKSKL---SELENLQKENTDLMKQIEELKNENENLK 879

Query: 867  ISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIE 926
              L +++    +L  +  R  L   +S + + ++ +L +N           + QK  EIE
Sbjct: 880  RELENLKLENESLKRENERLQLTADQSPQSKDKMIELLANQINQLESLVPELQQKTNEIE 939

Query: 927  DLEIEFNTQIESAIRDKKVLNEKYEK--NIEYVTQLEAQLQEYKNNIENLNMNV-----E 979
            +L+ E N QI+      K  NE  +K  + +   ++  + ++ K  IE+L   +      
Sbjct: 940  ELKKE-NKQIKEENEKLKKENEDLKKSGSNKSSEEINQEEEDLKKQIEDLKKALGYPQDG 998

Query: 980  ELNKMNLELIDKHVQ-KQQTQSPDYTEQY--INEINKLNALLKQKDEEIIALNQKINNAQ 1036
            + +K   ELI+++ + K++ +  +    Y   N+ +K  + L +++EE   L +K+++ +
Sbjct: 999  KEHKTPSELIEENEELKKKVEDLEKESGYPSDNKEHKSPSELLKENEE---LKKKVDDLE 1055

Query: 1037 --VSYMSMVSDYE--SKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQI 1092
              + Y     D++  S+L +   +L+   + ++R      D K H    + L++E ++  
Sbjct: 1056 KALGYPEDGKDHKSPSELIKENEELKKQNDALKRALGYPEDGKDHKSPSE-LIQENEELK 1114

Query: 1093 KELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQ 1152
            K++ + +          E    S  +    +    +              K    EE   
Sbjct: 1115 KKVADLEKALGYPADGQEHKTPSELLRENEELKKKLGISDSTTPSDNEDNK--SPEELRS 1172

Query: 1153 ERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKL--------- 1203
            E   L++Q   L   L   Y +  +     +EL   +   ++Q + LK  L         
Sbjct: 1173 ENKDLKKQIEDLKRALG--YPEDGKEHKTPSELIKENEELKKQNDSLKKALGYSEDGKDH 1230

Query: 1204 ---EQLNTENDNLLSTVAELRSSISSAVDQRGFEI-AELWKQH--LAQREADFQKTEHEL 1257
                +L  EN++L   V +L  ++    D +  +  +EL K++  L +   + +K   +L
Sbjct: 1231 KSPSELIKENEDLKKKVEDLEKALGFPEDGKEHKTPSELIKENEELKEETENIKKQIEDL 1290

Query: 1258 RVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQE--KYAD 1315
            +  L   E   E    S   +  EE  K     Q  +L+ KL    E   +  +  K  +
Sbjct: 1291 KRALGYPEDGKEHKTPSELINENEELKK-----QNENLKKKLGISGESSTDKSDSNKTPE 1345

Query: 1316 VINQIE-ILRSEIEDEKVAF----XXXXXXXXXXXXXXXXDLRTENQSYKQ--------M 1362
             I Q    L+ +IED K A                     +L+ +N   K+         
Sbjct: 1346 EIKQENGELKKQIEDLKKALGYPEDGKEHKSPSELIKENEELKKQNDDLKRALGYPEDGK 1405

Query: 1363 QEQSILNINEENAQLKK-------SSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSE 1415
              ++   + +EN +LKK       SS             +ND + KV +L   L      
Sbjct: 1406 DHKTPSELIKENEELKKKLGISGESSTEESKSYEELKDLINDLKKKVEDLEKALGYPSD- 1464

Query: 1416 IYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIED-LTYEKESELAILRLKMHENANHYE 1474
               K H+    L + NDE +     L +     ED   ++  SEL     ++ +     E
Sbjct: 1465 --GKDHKSPSELLKENDELKKQNDDLKKALGYPEDGKEHKSPSELIKENEELKKKLGLSE 1522

Query: 1475 TMQKESEIERVKLIEELNVKITESVSLNKQVAELNKAL-EEEVAKTNEMQTALENQEIEI 1533
                +S+ +  K  EEL     E+  L KQ+  L + L   E    ++  + L  +  E+
Sbjct: 1523 ESSTDSKADN-KSPEELK---NENNELKKQIEALKRVLGYPEDGNEHKTPSELIKENEEL 1578

Query: 1534 VTLNDEI 1540
               ND +
Sbjct: 1579 KKQNDNL 1585



 Score = 91.1 bits (216), Expect = 2e-16
 Identities = 267/1338 (19%), Positives = 551/1338 (41%), Gaps = 118/1338 (8%)

Query: 297  KQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATM--GT 354
            K+ +E   E+     E G  E    +EL K+ E L+     I++  ++L+  L     G 
Sbjct: 1244 KKKVE-DLEKALGFPEDGK-EHKTPSELIKENEELKEETENIKKQIEDLKRALGYPEDGK 1301

Query: 355  ESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVI 414
            E K  S    +   L  +K   N   K+       + ++ +  T ++I K E  +L+  I
Sbjct: 1302 EHKTPSELINENEEL--KKQNENLKKKLGISGESSTDKSDSNKTPEEI-KQENGELKKQI 1358

Query: 415  QSLNKDLVDKEYVISEKDTXXXXXXXXXXGK--DTLIAQLQL--EHQQHMEGPSLIHVGT 470
            + L K L   E     K             K  D L   L    + + H     LI    
Sbjct: 1359 EDLKKALGYPEDGKEHKSPSELIKENEELKKQNDDLKRALGYPEDGKDHKTPSELIKENE 1418

Query: 471  NTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVK 530
              +    I+      + +  +E+KD+ + DL +K++  E+ +   +D  D  + + + +K
Sbjct: 1419 ELKKKLGISGESSTEESKSYEELKDL-INDLKKKVEDLEKALGYPSDGKDHKSPSEL-LK 1476

Query: 531  SNHKLKLKQ--MQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDY 588
             N +LK +   ++K +  + +    +K    L +E   L +K+   EE   + +    D 
Sbjct: 1477 ENDELKKQNDDLKKAL-GYPEDGKEHKSPSELIKENEELKKKLGLSEESSTDSK---ADN 1532

Query: 589  DSGRMIESDVYKKMIEMENLAETRLKAISLLESQK-FDLVQELHILQQKYDEVEDKLADI 647
             S   ++++  +   ++E L           E +   +L++E   L+++ D ++  L   
Sbjct: 1533 KSPEELKNENNELKKQIEALKRVLGYPEDGNEHKTPSELIKENEELKKQNDNLKRALGYP 1592

Query: 648  SQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKE-----QLYGTIKDLEND 702
               +  +  SE+ +     +I+ L     +L   +   + DK+     +L    ++L+ +
Sbjct: 1593 EDGKDHKSPSELIA-----EIEELKKENDDLKRALGYPEDDKDHKSPSELIKENEELKKE 1647

Query: 703  KEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKI-QTQFGIDAKIQERD 761
             +D+  +L    + + + ++  E++  ++I +L   + + E  K  +T   +  + +E  
Sbjct: 1648 NDDLKKRLGISGESSAEESNSPEELK-KQIEDLKKALGYPEDGKEHKTPSELIKENEELK 1706

Query: 762  LYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQ-----KAYSEY 816
               + ++  L   +        S  + E+    L++K + L   L   Q     K+ SE 
Sbjct: 1707 KQNDALKRALGYPEDGKDHKSPSELIQENEE--LKKKVEDLEKALGYPQDGKDHKSPSEL 1764

Query: 817  TIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQK-----KNQILLEENQNLQISLSD 871
              + +EL  +L +  +      K   E+++ENK L+K     K  +   E+     S S+
Sbjct: 1765 LKENEELKKKLGISDESSTEDNKSPEELKNENKYLKKQIEGLKKALGYPEDGKEHKSPSE 1824

Query: 872  MQQHYNALVEKANRTD--LAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLE 929
            + Q    L +K +  +  L   E  K      +L    + +  E+Q L  +  +  + L 
Sbjct: 1825 LIQENEDLKKKVSDLEKALGYPEDGKEHKSPSELLKENEELKKENQRLKKENAELKKRLG 1884

Query: 930  IEFNTQI-----ESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKN--NIENLNMNVEELN 982
            I  +  I     ES   D+   N+  E+    +  L+ QL++ KN  + EN++    E+ 
Sbjct: 1885 IPVDQIIEGIMNESTASDESEDNKSPEELKREIENLKKQLEDLKNSGSQENVDEENNEMK 1944

Query: 983  KMNLELIDKHVQK--QQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYM 1040
            +    LID   Q   ++ +  D  +Q +++ N+   LLK K E+I  +N++ +N  +  +
Sbjct: 1945 EGADNLIDALQQSVDEKNKQIDDLQQKLDDQNREIELLKAKVEQIENINEEEDNEDI-VV 2003

Query: 1041 SMVSDYESKLAQFTTKLENMEEEMQRVSKQL--LDSKQHNEELQILVREQDDQIKELKET 1098
            +   D E +      + E+ EE  +R+++Q+  L  K   ++   L  +Q    K+ + +
Sbjct: 2004 ASTRDVELE----NVEEESPEEAKERLAEQISQLQDKLTEKKKNSLQMKQALASKDAEIS 2059

Query: 1099 KLTFEMNIPKTEGMIISSTIEPMSDDANN-VDXXXXXXXXXXXXLKVQEEEEFIQERSVL 1157
            KL  E+   K+E       +E ++++    ++               + EE+F+ +   L
Sbjct: 2060 KLNEEIEQIKSEKEDQDKELEKLNNELTEALEKLENGKKKSSQEQNNENEEDFVDDIEKL 2119

Query: 1158 QEQSAKLNTELQECYTKIIQLETLNTEL----TGHDVVNQEQINQLKSKLEQLNTENDNL 1213
            +E+   L +E +    +  + E L   L      +D +N+   ++ ++K+++L +E   L
Sbjct: 2120 KEERENLKSENESLKNQAPENEGLKKSLENLKKSNDDLNKSNEDK-ENKIKELESEISKL 2178

Query: 1214 LSTVAELRSSISS---AVDQRGFEIAELWKQHLAQREADFQKT-EHELRVQL-----SAF 1264
             S + EL  +       ++    +++ +   +L   E D       ++ V       +  
Sbjct: 2179 KSEINELEQNNKDKDREIEILSSKVSSIENVNLDDDEDDITVVGTRDISVDETIPTDNET 2238

Query: 1265 ESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEE----HLRNLQEKYADVINQI 1320
            E+K E   ++  +    ETN+     Q  + + K Q KE+     ++ L++  A    ++
Sbjct: 2239 ETKTEPETNTNTNENTNETNEENVSSQEGNNEEKNQSKEDKKKLRIQQLKQLLASKQGEV 2298

Query: 1321 EILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKS 1380
            + L+S+ +D K +                 +L  E ++    +E  +  I+E+ A     
Sbjct: 2299 DALKSQNDDLK-SENETLSKSNHELGTKTKELEEEIENINNNKEGEV--IDEKEA---SD 2352

Query: 1381 SXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQ 1440
                           N+ + + L+   + +L + E  QK ++       + DE   + ++
Sbjct: 2353 VEVVCSTRDVDFEYENENDPETLKSLLKSKLSELENLQKENK------AKEDEITKLNEE 2406

Query: 1441 LVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEEL--NVKITES 1498
            L + E         K  ELA    +++   N      +  +  R KLIE+L  N K  E 
Sbjct: 2407 LAKSED-------AKRRELAETAERLNNEINTLHDELQNEQNARQKLIEDLQSNNKEPEK 2459

Query: 1499 VS-------LNKQVAELNKALEEEVAKTNEMQTALENQEIE-----IVTLNDEITNLQNM 1546
                     L K+  E+NKALEE + + NE   AL ++E E     +  L  +I  L N 
Sbjct: 2460 DDNGDFMNVLEKKSDEINKALEEILHRQNEEIKALRDREAEKNKQTVDDLQKQIAMLNNK 2519

Query: 1547 VRAS----SSKIQKHVSF 1560
            ++ S    + ++QK + F
Sbjct: 2520 LKPSDQTDNDQLQKELMF 2537



 Score = 63.7 bits (148), Expect = 4e-08
 Identities = 88/426 (20%), Positives = 185/426 (43%), Gaps = 31/426 (7%)

Query: 1192 NQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQ 1251
            N E +N   S+L+Q N++N  L+  +  L  +    V+    E  E +  + AQ  A   
Sbjct: 161  NLESLNDELSRLKQ-NSQNSELVKVLDNLTRTTDYVVNLENNENLERYTTYDAQLRA-IS 218

Query: 1252 KTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQE 1311
            +    L  ++++  ++ ++L  S QS  Q   ++   +    S   +  +K   + +  E
Sbjct: 219  QAALRLSTKVNSLNAELQELKHS-QSEMQIIVSQYKEVVPKISFHIETIEKLVSINDTDE 277

Query: 1312 KYADVI---NQIEILRSEIE---DEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQ 1365
               + +    +++ +RSE++   D                         ++   +Q + +
Sbjct: 278  DDKNPLIFPQRLKRIRSEVQRLFDNNEKTNKELQKLKEQLELYENMKNGQSMKERQAELE 337

Query: 1366 SI-LNINEENAQLKK-SSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEY 1423
            S+ L + ++NA+L++  +             +   E +V  L +++  ++S+I  K    
Sbjct: 338  SLRLELEKKNAELEQLKARYQSKQDPQLLAEIERIENEVQNLKNKIADRESQI--KALNL 395

Query: 1424 TITLTQRNDE-----FENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQK 1478
             I   Q +DE      EN+ +++ + +K+IED    K+ E+ +L+ K+ +     E  + 
Sbjct: 396  LIAQYQTDDEDKKEIIENLEKEIKDLKKQIED----KDKEIEVLKAKIAKIEEIPEDEED 451

Query: 1479 ESEI---ERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVT 1535
            E  +    R   + + N +  E VSL  QV +L + L+++     +M+ AL +++ EI  
Sbjct: 452  EDIVVAGTRDVDLGDFNEEEAEQVSLEDQVKQLKEKLDDKKKNGVQMKQALASKDAEIEK 511

Query: 1536 LNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDLAMYM 1595
            LN++I  L++        I++  +  SD +   DE       K+L+D +     DLA   
Sbjct: 512  LNEQIQELKDRNDKQEQNIEELNTKNSDLQNSNDEY------KKLIDELQNQLKDLAKNK 565

Query: 1596 LHQRDV 1601
                D+
Sbjct: 566  AESSDL 571



 Score = 63.3 bits (147), Expect = 5e-08
 Identities = 282/1447 (19%), Positives = 589/1447 (40%), Gaps = 120/1447 (8%)

Query: 212  EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271
            ED K+   +  +  +A +    D  +    D++S++    +L ++N  LE    E+  E 
Sbjct: 745  EDKKKLRIQQLKQLLASKQGEVDALKSQNDDLKSEN---ETLSKSNHELETKNKELEEEI 801

Query: 272  SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELT----KK 327
              +    E                + + ++   E + + E   SL  + ++EL     + 
Sbjct: 802  ENINNNKEGEVIDEKEASDVEVVCSTRDVDFEYENENDPETLKSLLKSKLSELENLQKEN 861

Query: 328  IELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWS 387
             +L++ +  +++  N+ L+ +L  +  E++++   +++   L + +S ++    ++   +
Sbjct: 862  TDLMKQIE-ELKNENENLKRELENLKLENESLKRENER-LQLTADQSPQSKDKMIELLAN 919

Query: 388  QLSS-ETLNQDTDKKINK-NEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGK 445
            Q++  E+L  +  +K N+  E+ K    I+  N+ L  +   + +  +           +
Sbjct: 920  QINQLESLVPELQQKTNEIEELKKENKQIKEENEKLKKENEDLKKSGSNKSSEEINQEEE 979

Query: 446  DTL--IAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIE 503
            D    I  L+       +G          E+  E+ K  E L++E      +   K   E
Sbjct: 980  DLKKQIEDLKKALGYPQDGKEHKTPSELIEENEELKKKVEDLEKESGYPSDNKEHKSPSE 1039

Query: 504  KLKSAEEQITQLND--------EIDAANKNMIK-VKSNHKLKLKQ-MQKTIDNFSKVSDS 553
             LK  EE   +++D        E    +K+  + +K N +LK +    K    + +    
Sbjct: 1040 LLKENEELKKKVDDLEKALGYPEDGKDHKSPSELIKENEELKKQNDALKRALGYPEDGKD 1099

Query: 554  NKEIVRLTEELHHLSQKVAELEEEKG---NLQLHLVDYDSGRMIESDVYKKMIEMENLAE 610
            +K    L +E   L +KVA+LE+  G   + Q H    +  R  E++  KK + + +   
Sbjct: 1100 HKSPSELIQENEELKKKVADLEKALGYPADGQEHKTPSELLR--ENEELKKKLGISDSTT 1157

Query: 611  TR----LKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVH--L 664
                   K+   L S+  DL +++  L++     ED     +  +  +   E+K  +  L
Sbjct: 1158 PSDNEDNKSPEELRSENKDLKKQIEDLKRALGYPEDGKEHKTPSELIKENEELKKQNDSL 1217

Query: 665  EEQIDALSASK-----KELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMD 719
            ++ +      K      EL    E+LK   E L   +   E+ KE         I+EN +
Sbjct: 1218 KKALGYSEDGKDHKSPSELIKENEDLKKKVEDLEKALGFPEDGKEH--KTPSELIKENEE 1275

Query: 720  LTDKLEKMSAEKISELLAKINHEEQSKI-QTQFGIDAKIQERDLYIENIESEL------S 772
            L ++ E +  ++I +L   + + E  K  +T   +  + +E     EN++ +L      S
Sbjct: 1276 LKEETENIK-KQIEDLKRALGYPEDGKEHKTPSELINENEELKKQNENLKKKLGISGESS 1334

Query: 773  KYKSRICRLEESIAVME-DRRYSLERKADQLGSYLQEKQ-KAYSEYTIQEDELVN----- 825
              KS   +  E I     + +  +E     LG     K+ K+ SE   + +EL       
Sbjct: 1335 TDKSDSNKTPEEIKQENGELKKQIEDLKKALGYPEDGKEHKSPSELIKENEELKKQNDDL 1394

Query: 826  RLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANR 885
            + A+    D    K   E+  EN+EL+KK  I  E +     S  +++   N L +K   
Sbjct: 1395 KRALGYPEDGKDHKTPSELIKENEELKKKLGISGESSTEESKSYEELKDLINDLKKKVE- 1453

Query: 886  TDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKV 945
             DL   ++  Y +  +D +S    +  E+  L    KK+ +DL+       +   ++ K 
Sbjct: 1454 -DL--EKALGYPSDGKDHKSP-SELLKENDEL----KKQNDDLKKALGYPEDG--KEHKS 1503

Query: 946  LNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTE 1005
             +E  ++N E   +L    +E   + +  N + EEL   N EL  K ++  + +   Y E
Sbjct: 1504 PSELIKENEELKKKLGLS-EESSTDSKADNKSPEELKNENNEL-KKQIEALK-RVLGYPE 1560

Query: 1006 QYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQ 1065
               NE    + L+K+ +EE+   N  +  A + Y     D++S  ++   ++E +++E  
Sbjct: 1561 DG-NEHKTPSELIKE-NEELKKQNDNLKRA-LGYPEDGKDHKSP-SELIAEIEELKKEND 1616

Query: 1066 RVSKQL---LDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMS 1122
             + + L    D K H    + L++E ++  KE  + K    + I        S++ E + 
Sbjct: 1617 DLKRALGYPEDDKDHKSPSE-LIKENEELKKENDDLKK--RLGISGESSAEESNSPEELK 1673

Query: 1123 DDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLN 1182
                 ++             + +   E I+E   L++Q+  L   L   Y +  +     
Sbjct: 1674 ---KQIEDLKKALGYPEDGKEHKTPSELIKENEELKKQNDALKRALG--YPEDGKDHKSP 1728

Query: 1183 TELTGHDVVNQEQINQLKSKLEQLNTENDN-----LLSTVAELRSSISSAVDQRGFEIAE 1237
            +EL   +   ++++  L+  L       D+     LL    EL+  +  + D+   E  +
Sbjct: 1729 SELIQENEELKKKVEDLEKALGYPQDGKDHKSPSELLKENEELKKKLGIS-DESSTEDNK 1787

Query: 1238 LWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQN 1297
               + L       +K    L+  L   E   E    S      E+  K V+   +     
Sbjct: 1788 S-PEELKNENKYLKKQIEGLKKALGYPEDGKEHKSPSELIQENEDLKKKVS--DLEKALG 1844

Query: 1298 KLQDKEEHL--RNLQEKYADVINQIEILRSEIED--EKVAFXXXXXXXXXXXXXXXXDLR 1353
              +D +EH     L ++  ++  + + L+ E  +  +++                  D  
Sbjct: 1845 YPEDGKEHKSPSELLKENEELKKENQRLKKENAELKKRLGIPVDQIIEGIMNESTASDES 1904

Query: 1354 TENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKD 1413
             +N+S ++++ + I N+ ++   LK S               N+ +     L   L+   
Sbjct: 1905 EDNKSPEELKRE-IENLKKQLEDLKNSGSQENVDEEN-----NEMKEGADNLIDALQQSV 1958

Query: 1414 SEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESE-LAILRLKMHENANH 1472
             E  ++  +    L  +N E E ++ ++    ++IE++  E+++E + +   +  E  N 
Sbjct: 1959 DEKNKQIDDLQQKLDDQNREIELLKAKV----EQIENINEEEDNEDIVVASTRDVELENV 2014

Query: 1473 YETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNE----MQTALEN 1528
             E   +E++    + I +L  K+TE    + Q+ +   + + E++K NE    +++  E+
Sbjct: 2015 EEESPEEAKERLAEQISQLQDKLTEKKKNSLQMKQALASKDAEISKLNEEIEQIKSEKED 2074

Query: 1529 QEIEIVTLNDEIT----NLQNMVRASSSK--IQKHVSFASDTKQGRDEQLD-NTMNKELL 1581
            Q+ E+  LN+E+T     L+N  + SS +   +    F  D ++ ++E+ +  + N+ L 
Sbjct: 2075 QDKELEKLNNELTEALEKLENGKKKSSQEQNNENEEDFVDDIEKLKEERENLKSENESLK 2134

Query: 1582 DAVPRAE 1588
            +  P  E
Sbjct: 2135 NQAPENE 2141



 Score = 55.6 bits (128), Expect = 1e-05
 Identities = 108/533 (20%), Positives = 219/533 (41%), Gaps = 51/533 (9%)

Query: 1076 QHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNV-DXXXXX 1134
            Q N E+  L  + +D   +    +L  +          I+S I P+    +++ D     
Sbjct: 88   QQNNEIDSLRAKYNDARAKSAAYELELQKAKQSLISRTINSNIHPLRSIGHDLEDEKESL 147

Query: 1135 XXXXXXXLKVQEE--EEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVN 1192
                   + + +E  E    E S L++ S   N+EL     K++   T  T+     VVN
Sbjct: 148  SDSISSTISIYDENLESLNDELSRLKQNSQ--NSEL----VKVLDNLTRTTDY----VVN 197

Query: 1193 QEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQK 1252
             E        LE+  T  D  L  +++    +S+ V+    E+ EL  +H +Q E     
Sbjct: 198  LEN----NENLERYTTY-DAQLRAISQAALRLSTKVNSLNAELQEL--KH-SQSEMQIIV 249

Query: 1253 TEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQ---DKEE----H 1305
            ++++  V   +F  +  + L S+  + +++ N ++  +++  +++++Q   D  E     
Sbjct: 250  SQYKEVVPKISFHIETIEKLVSINDTDEDDKNPLIFPQRLKRIRSEVQRLFDNNEKTNKE 309

Query: 1306 LRNLQEK---YADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQM 1362
            L+ L+E+   Y ++ N   +   + E E +                    + + Q   ++
Sbjct: 310  LQKLKEQLELYENMKNGQSMKERQAELESLRLELEKKNAELEQLKARYQSKQDPQLLAEI 369

Query: 1363 QE-----QSILN-INEENAQLKKSSXXXXXXXXXXXXR---VNDAEAKVLELTHQLELKD 1413
            +      Q++ N I +  +Q+K  +            +   + + E ++ +L  Q+E KD
Sbjct: 370  ERIENEVQNLKNKIADRESQIKALNLLIAQYQTDDEDKKEIIENLEKEIKDLKKQIEDKD 429

Query: 1414 SEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHY 1473
             EI  +  +  I   +   E E   + +V    R  DL    E E    ++ + +     
Sbjct: 430  KEI--EVLKAKIAKIEEIPEDEE-DEDIVVAGTRDVDLGDFNEEEAE--QVSLEDQVKQL 484

Query: 1474 ETMQKESEIERVKLIEELNVKITESVSLNKQVAEL---NKALEEEVAKTNEMQTALENQE 1530
            +    + +   V++ + L  K  E   LN+Q+ EL   N   E+ + + N   + L+N  
Sbjct: 485  KEKLDDKKKNGVQMKQALASKDAEIEKLNEQIQELKDRNDKQEQNIEELNTKNSDLQNSN 544

Query: 1531 IEIVTLNDEITN-LQNMVR--ASSSKIQKHVSFASDTKQGRDEQLDNTMNKEL 1580
             E   L DE+ N L+++ +  A SS +    +   D+++  DE  +   NKEL
Sbjct: 545  DEYKKLIDELQNQLKDLAKNKAESSDLNNSENTKQDSEKAEDENAETKSNKEL 597


>UniRef50_A2DDX5 Cluster: Viral A-type inclusion protein, putative;
            n=1; Trichomonas vaginalis G3|Rep: Viral A-type inclusion
            protein, putative - Trichomonas vaginalis G3
          Length = 1794

 Score =  196 bits (479), Expect = 3e-48
 Identities = 288/1391 (20%), Positives = 596/1391 (42%), Gaps = 121/1391 (8%)

Query: 234  DEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXX 293
            D+  +L K++  KD +I+ L  AN + E  + + + ++  L Q  E              
Sbjct: 258  DKISQLEKELAEKDDQINEL--ANLIEENDKKQGTQQNQNLNQNDEDAIQSLVTKYEEEI 315

Query: 294  XLAKQSIEPSCEEK-TEIEE-KGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLAT 351
               K++ +   E    +I E K SL+     E++ + +L E +   I QT+K+ E K+  
Sbjct: 316  DDIKKNNQNEKENLINQINELKNSLK---NKEISSENDLNE-MKIIIEQTSKDYETKIQD 371

Query: 352  MGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINK--NEIAK 409
            + T  +  S    + S  +     +N      S   Q S++   +   K+I+    E  K
Sbjct: 372  LMTNLEENSQKLNEMSQKLKESEEKNQKLNEMS-MLQASNDAEKEKFIKEISNLTKENEK 430

Query: 410  LEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQ-----LEHQQHMEGPS 464
            L+ V+    K+  + E +++E                 L  +++     ++ +Q+ +   
Sbjct: 431  LQTVLNENEKNRTENERLVAENQKLNSDLHEIGEVNKNLQTEIEKLTEIMKSEQNNKENE 490

Query: 465  LIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDE----ID 520
            ++ + +  E+  ++  +Q +L Q  N E K+   +DL +KLK  E +  +LND+    I+
Sbjct: 491  MMSLLSQKEE--QVQALQVKLNQT-NQE-KEKQFEDLSQKLKQLEAEKQKLNDDYESKIN 546

Query: 521  AANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGN 580
               +N  +  +N++ ++K+M    +N    + S +E + L E+  +  +KV  LEE+   
Sbjct: 547  EIQQNDNETFTNYQNQIKEMMINNENLQNENKSLQEKISLNEKSDN--EKVLSLEEQLKE 604

Query: 581  LQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEV 640
             +      +S   ++  +      +ENL +   +       +   L  EL  +Q   + +
Sbjct: 605  SK------NSISSLQEQLKSSQQTIENLEKNISEKSETYNEKIKSLTDELSTIQNTNENL 658

Query: 641  EDKLADISQ-LQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDL 699
            ++++  + + L +++     K ++LEEQ   L  S+ E+ +  E  KL K          
Sbjct: 659  QNEIKSLQEKLSNNEKNDNEKILNLEEQ---LKNSQNEVRIGQE--KLSK---------F 704

Query: 700  ENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQE 759
            EN+ + + +KL + +++ +  + K+++   ++   L  KI+  E+S  +    ++ ++  
Sbjct: 705  ENEYDQMRSKL-SLMEKELSTSQKMKESLQKEKESLQEKISLSEKSDNEKVLSLEEQLNN 763

Query: 760  RDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQ 819
                I N E    + +S++  L E ++  +    +LE K         EK K+Y E    
Sbjct: 764  SKNMITNYEQNEKELQSQLSTLNEELSTSKKMIETLEEKISNNEKNGDEKVKSYEEQLNS 823

Query: 820  EDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNAL 879
                +N L  +   +   E+++  +E +NK+LQ+K  I L E      S SD ++ Y A 
Sbjct: 824  YRNTINELQQITQSN---EEKIKSLESQNKDLQEK--ISLSEK-----SESDKEKSYEAQ 873

Query: 880  VEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEF-NTQIE- 937
            +   N    A++  +    Q+  L+  +  I           + +I+++ I   N Q E 
Sbjct: 874  LN--NLKQQAQNHISSLNQQIESLKQEISSIQQNDNETFTNYQNQIKEMMINNENLQNEV 931

Query: 938  SAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEEL-------------NKM 984
             ++++K  LNEK +   E V  LE QL   KN I N   N +EL             +K 
Sbjct: 932  QSLQEKISLNEKSDN--EKVLSLEEQLNNSKNMITNYEQNEKELQSQLSTLNEELSTSKK 989

Query: 985  NLELIDKHV---QKQQTQSPDYTEQYI----NEINKLNALLKQKDEEIIALNQKINNAQV 1037
             +E +++ +   +K   +     E+ +    N I+ L   LK   + I  L + I+    
Sbjct: 990  MIETLEEKISNNEKSDNEKVLSLEEQLKESKNSISSLQEQLKSSQQTIENLEKNISEKSE 1049

Query: 1038 SYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKE 1097
            +Y   +     +L+    K EN++ E++ + ++L ++++++ E   L  EQ + +K+  +
Sbjct: 1050 TYNEKIKSLTDELSTIQNKNENLQNEIKSLQEKLSNNEKNDNEKVKLYEEQLNSLKKEND 1109

Query: 1098 TKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVL 1157
                   +I K++     +    + +   N++            + + E+ +  +  S  
Sbjct: 1110 NLKQEMSDIQKSDNETFENYQNQIKEMMQNLEEAENKVSTLQEQISMNEKSDSEKVTSY- 1168

Query: 1158 QEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTV 1217
            + + A+++ E +E   K    + + +         +E+IN L  ++   + E       +
Sbjct: 1169 EAKIAQMHQEKKELEKKFTAAKQIVSNNRQEKKEMEEKINSLTKQVSDKDEELQKSKEEI 1228

Query: 1218 AELRSSISSAVDQRGFEIAELWKQHLAQREADFQK-TEHELRVQLSAFESK-YEQLLDSV 1275
              L   ++S   ++  ++AE  +Q L++ E+  QK TE E  VQ    ++K  E L   +
Sbjct: 1229 ESLNHKVTSNEAEKQ-KVAEDLQQKLSEIESLKQKLTEKENDVQKVTEQNKSIEDLKQQI 1287

Query: 1276 QSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFX 1335
                +  T+   T+E ++    +L+ K++      EK  ++I     L  ++E  K    
Sbjct: 1288 SEKEKVITDNQKTIENLSFELTELKQKKDD----SEKDKEIIQN---LTKDLEKMKADLD 1340

Query: 1336 XXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRV 1395
                           ++    Q+  +  E + + ++EEN +L K              +V
Sbjct: 1341 SKQKENDEIRSRLNREIEDNKQALAKAVETAKI-LSEENEKLTKQME-----------QV 1388

Query: 1396 NDAEAKVLE-LTHQLELKDSEIYQKTHEYTITLTQRN---DEFENVRQQLVEYEKRIEDL 1451
            + +E +  + L+ ++   +S +       T  L  RN    E      +L E +   + +
Sbjct: 1389 SSSETEKCQVLSSKISTLESRLQSSETRATSVLEDRNRLSSELLRTMSELKESKNEKDKI 1448

Query: 1452 TYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAEL--- 1508
            T E   ++  L     E   +YE   K  E E+  L  ++N    +  +L K V  L   
Sbjct: 1449 TQEFNDKIKELESNSREQTANYEGKIKLLESEKSSLETKINEDQLKISNLEKNVQNLSNK 1508

Query: 1509 NKALEEEVAKTNEMQTALENQ----EIEIVTL---NDEITNLQNMVRASSSKIQKHVSFA 1561
            N   + EV+K  E  + L+NQ    E+EI+ +   ND +T+    +R S +K+Q++V+  
Sbjct: 1509 NSVSDNEVSKLKEDNSKLKNQISNFEVEIMQIKESNDLLTSQNEKLRESKNKLQQNVNDL 1568

Query: 1562 SDTKQGRDEQL 1572
              TK+   +++
Sbjct: 1569 EATKKDLTQKM 1579



 Score =  193 bits (470), Expect = 4e-47
 Identities = 280/1426 (19%), Positives = 599/1426 (42%), Gaps = 102/1426 (7%)

Query: 149  NTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXX 208
            N   EK+N ++ +      ++   +  +  +NE   IIE  +K                 
Sbjct: 321  NNQNEKENLINQINELKNSLKNKEISSENDLNEMKIIIEQTSKDYETKIQDLMTNLEENS 380

Query: 209  XXXEDTKQQMTKMQE-----NFIAM-EAEWKDEKQRLLKDIES---KDVRISSLEEANKL 259
                +  Q++ + +E     N ++M +A    EK++ +K+I +   ++ ++ ++   N+ 
Sbjct: 381  QKLNEMSQKLKESEEKNQKLNEMSMLQASNDAEKEKFIKEISNLTKENEKLQTVLNENEK 440

Query: 260  LEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEI--EEKGSLE 317
                   +  E+ KL  +L +                 ++++   E+ TEI   E+ + E
Sbjct: 441  NRTENERLVAENQKLNSDLHEIGE------------VNKNLQTEIEKLTEIMKSEQNNKE 488

Query: 318  IANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSG-- 375
               M+ L++K E ++ L  ++ QTN+E E +   +  + K + +  +K +     K    
Sbjct: 489  NEMMSLLSQKEEQVQALQVKLNQTNQEKEKQFEDLSQKLKQLEAEKQKLNDDYESKINEI 548

Query: 376  -RNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTX 434
             +N      +  +Q+    +N +  +  NK+   K+ +  +S N+ ++  E  + E    
Sbjct: 549  QQNDNETFTNYQNQIKEMMINNENLQNENKSLQEKISLNEKSDNEKVLSLEEQLKESKNS 608

Query: 435  XXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELND--E 492
                          I  L+    +  E  +   + + T++++ I    E L+ E+    E
Sbjct: 609  ISSLQEQLKSSQQTIENLEKNISEKSETYNE-KIKSLTDELSTIQNTNENLQNEIKSLQE 667

Query: 493  IKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNH---KLKLKQMQKTIDNFSK 549
                N K+  EK+ + EEQ+    +E+    + + K ++ +   + KL  M+K +    K
Sbjct: 668  KLSNNEKNDNEKILNLEEQLKNSQNEVRIGQEKLSKFENEYDQMRSKLSLMEKELSTSQK 727

Query: 550  VSDS-NKEIVRLTEELHHL----SQKVAELEEEKGNLQLHLVDYDSG-RMIESDVY---K 600
            + +S  KE   L E++       ++KV  LEE+  N +  + +Y+   + ++S +    +
Sbjct: 728  MKESLQKEKESLQEKISLSEKSDNEKVLSLEEQLNNSKNMITNYEQNEKELQSQLSTLNE 787

Query: 601  KMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCS-EI 659
            ++   + + ET  + IS  E    + V+        Y    ++L  I+Q   +++ S E 
Sbjct: 788  ELSTSKKMIETLEEKISNNEKNGDEKVKSYEEQLNSYRNTINELQQITQSNEEKIKSLES 847

Query: 660  KSVHLEEQIDALSASK----KELALVIENLKLDKEQLYGTI-KDLENDKEDIMNKLQNYI 714
            ++  L+E+I     S+    K     + NLK   +    ++ + +E+ K++I +  QN  
Sbjct: 848  QNKDLQEKISLSEKSESDKEKSYEAQLNNLKQQAQNHISSLNQQIESLKQEISSIQQNDN 907

Query: 715  QENMDLTDKLEKMSAE------KISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIE 768
            +   +  +++++M         ++  L  KI+  E+S  +    ++ ++      I N E
Sbjct: 908  ETFTNYQNQIKEMMINNENLQNEVQSLQEKISLNEKSDNEKVLSLEEQLNNSKNMITNYE 967

Query: 769  SELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLA 828
                + +S++  L E ++  +    +LE K         EK  +  E   +    ++ L 
Sbjct: 968  QNEKELQSQLSTLNEELSTSKKMIETLEEKISNNEKSDNEKVLSLEEQLKESKNSISSLQ 1027

Query: 829  V-LMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTD 887
              L    + +E     I  +++   +K + L +E   +Q    ++Q    +L EK +  +
Sbjct: 1028 EQLKSSQQTIENLEKNISEKSETYNEKIKSLTDELSTIQNKNENLQNEIKSLQEKLSNNE 1087

Query: 888  LAESESTK-YQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVL 946
              ++E  K Y+ QL  L+     +  E   +   +K + E  E  +  QI+  +++ +  
Sbjct: 1088 KNDNEKVKLYEEQLNSLKKENDNLKQEMSDI---QKSDNETFE-NYQNQIKEMMQNLEEA 1143

Query: 947  NEKYEKNIEYVTQLEAQLQE----YKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPD 1002
              K     E ++  E    E    Y+  I  ++   +EL K       K +     Q   
Sbjct: 1144 ENKVSTLQEQISMNEKSDSEKVTSYEAKIAQMHQEKKELEKKFTAA--KQIVSNNRQEKK 1201

Query: 1003 YTEQYINEINKL----NALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTT--- 1055
              E+ IN + K     +  L++  EEI +LN K+ + +     +  D + KL++  +   
Sbjct: 1202 EMEEKINSLTKQVSDKDEELQKSKEEIESLNHKVTSNEAEKQKVAEDLQQKLSEIESLKQ 1261

Query: 1056 KLENMEEEMQRVSKQ---LLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGM 1112
            KL   E ++Q+V++Q   + D KQ   E + ++ +    I+ L   +LT E+   K +  
Sbjct: 1262 KLTEKENDVQKVTEQNKSIEDLKQQISEKEKVITDNQKTIENLS-FELT-ELKQKKDDSE 1319

Query: 1113 IISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQE--QSAKLNTELQE 1170
                 I+ ++ D   +             ++ +   E    +  L +  ++AK+ +E  E
Sbjct: 1320 KDKEIIQNLTKDLEKMKADLDSKQKENDEIRSRLNREIEDNKQALAKAVETAKILSEENE 1379

Query: 1171 CYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQ 1230
              TK  Q+E +++  T    V   +I+ L+S+L+   T   ++L     L S +   + +
Sbjct: 1380 KLTK--QMEQVSSSETEKCQVLSSKISTLESRLQSSETRATSVLEDRNRLSSELLRTMSE 1437

Query: 1231 RGFEIAELWKQHLAQREAD-FQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETN----K 1285
               + ++  K  + Q   D  ++ E   R Q + +E K + LL+S +SS + + N    K
Sbjct: 1438 --LKESKNEKDKITQEFNDKIKELESNSREQTANYEGKIK-LLESEKSSLETKINEDQLK 1494

Query: 1286 IVTMEQ-VTSLQNKLQDKEEHLRNLQEKYADVINQI-----EILR-SEIEDEKVAFXXXX 1338
            I  +E+ V +L NK    +  +  L+E  + + NQI     EI++  E  D   +     
Sbjct: 1495 ISNLEKNVQNLSNKNSVSDNEVSKLKEDNSKLKNQISNFEVEIMQIKESNDLLTSQNEKL 1554

Query: 1339 XXXXXXXXXXXXDLRTENQSYKQMQEQSILNINE-ENAQLKKSSXXXXXXXXXXXXRVND 1397
                        DL    +   Q   Q   +  E E   L ++             ++  
Sbjct: 1555 RESKNKLQQNVNDLEATKKDLTQKMAQMKCDSRENEINSLLETKKSLEEKISVLQNQIAT 1614

Query: 1398 AEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKES 1457
                  +L  Q+ELK+ +I  +  +Y   ++Q ++    +R++ +E E +I+++ Y+ E 
Sbjct: 1615 ILKDKSDLAEQIELKEIDIKDQMLKYKEQMSQNDNVVFEMRKEKIELENQIKEIKYQNEL 1674

Query: 1458 ELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNK 1503
             ++ +  +  E    YE    E  +   K +++L+ K+ + VS N+
Sbjct: 1675 NVSKMNQEKEELTKSYE----EKILLYAKKVQQLSRKL-QKVSENQ 1715



 Score =  180 bits (438), Expect = 3e-43
 Identities = 248/1280 (19%), Positives = 568/1280 (44%), Gaps = 113/1280 (8%)

Query: 337  QIRQTNKELENKLATMGTESKAVS--SPSKKGSPLISRKSGRNTASKMKSP-WSQLSSET 393
            ++ + N+ L+ +LA+   +S+ +   S ++  S      + +N+   M    + +     
Sbjct: 187  ELMRENESLKEQLASKPAQSQDLLDFSSNQNNSNFNQSSNQQNSQQNMLLDLFGEQQPAN 246

Query: 394  LNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGK--DTLIAQ 451
             +Q+TD +   ++I++LE  +   +  + +   +I E D            +  +  I  
Sbjct: 247  QSQNTDIQRLNDKISQLEKELAEKDDQINELANLIEENDKKQGTQQNQNLNQNDEDAIQS 306

Query: 452  LQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVN-VKDLIEKL-KSAE 509
            L  ++++ ++     +       +N+I +++  LK +      D+N +K +IE+  K  E
Sbjct: 307  LVTKYEEEIDDIKKNNQNEKENLINQINELKNSLKNKEISSENDLNEMKIIIEQTSKDYE 366

Query: 510  EQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSN--------KEIVRLT 561
             +I  L   ++  ++ + ++    K   ++ QK ++  S +  SN        KEI  LT
Sbjct: 367  TKIQDLMTNLEENSQKLNEMSQKLKESEEKNQK-LNEMSMLQASNDAEKEKFIKEISNLT 425

Query: 562  EELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLES 621
            +E   L   + E E+ +   +  + +    + + SD+++     +NL     K   +++S
Sbjct: 426  KENEKLQTVLNENEKNRTENERLVAE---NQKLNSDLHEIGEVNKNLQTEIEKLTEIMKS 482

Query: 622  QKFDLVQEL-HILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELAL 680
            ++ +   E+  +L QK ++V+     ++Q   ++   E +   L +++  L A K++L  
Sbjct: 483  EQNNKENEMMSLLSQKEEQVQALQVKLNQTNQEK---EKQFEDLSQKLKQLEAEKQKLND 539

Query: 681  VIENLKLDKEQLYG--TIKDLENDKEDIMNKLQNYIQENMDLTDKL---EKMSAEKISEL 735
              E+ K+++ Q     T  + +N  +++M   +N   EN  L +K+   EK   EK+  L
Sbjct: 540  DYES-KINEIQQNDNETFTNYQNQIKEMMINNENLQNENKSLQEKISLNEKSDNEKVLSL 598

Query: 736  LAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSL 795
              ++   + S    Q  + +  Q  +   +NI  +   Y  +I  L + ++ +++   +L
Sbjct: 599  EEQLKESKNSISSLQEQLKSSQQTIENLEKNISEKSETYNEKIKSLTDELSTIQNTNENL 658

Query: 796  ERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKN 855
            + +   L   L   +K  +E  +  +E   +L    +  R+ +++L + E+E  +++ K 
Sbjct: 659  QNEIKSLQEKLSNNEKNDNEKILNLEE---QLKNSQNEVRIGQEKLSKFENEYDQMRSKL 715

Query: 856  QILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQ 915
             ++ +E    Q     +Q+   +L EK + ++ +++E       L +  +N K +   ++
Sbjct: 716  SLMEKELSTSQKMKESLQKEKESLQEKISLSEKSDNEKV---LSLEEQLNNSKNMITNYE 772

Query: 916  TLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKY---EKN-IEYVTQLEAQLQEYKNNI 971
                Q +KE++      N ++ ++ +  + L EK    EKN  E V   E QL  Y+N I
Sbjct: 773  ----QNEKELQSQLSTLNEELSTSKKMIETLEEKISNNEKNGDEKVKSYEEQLNSYRNTI 828

Query: 972  ENLNM-------NVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNAL----LKQ 1020
              L          ++ L   N +L +K    ++++S D  + Y  ++N L       +  
Sbjct: 829  NELQQITQSNEEKIKSLESQNKDLQEKISLSEKSES-DKEKSYEAQLNNLKQQAQNHISS 887

Query: 1021 KDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQL-LDSKQHNE 1079
             +++I +L Q+I++ Q +     ++Y++++ +     EN++ E+Q + +++ L+ K  NE
Sbjct: 888  LNQQIESLKQEISSIQQNDNETFTNYQNQIKEMMINNENLQNEVQSLQEKISLNEKSDNE 947

Query: 1080 ELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXX 1139
            ++  L    ++Q+   K     +E N  + +   +S+  E +S     ++          
Sbjct: 948  KVLSL----EEQLNNSKNMITNYEQNEKELQSQ-LSTLNEELSTSKKMIETLEEKISNN- 1001

Query: 1140 XXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQL 1199
               +  + E+ +     L+E    +++  ++  +    +E L   ++       E+I  L
Sbjct: 1002 ---EKSDNEKVLSLEEQLKESKNSISSLQEQLKSSQQTIENLEKNISEKSETYNEKIKSL 1058

Query: 1200 KSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELR- 1258
              +L  +  +N+NL + +  L+  +S+  ++   E  +L+++ L   + +    + E+  
Sbjct: 1059 TDELSTIQNKNENLQNEIKSLQEKLSNN-EKNDNEKVKLYEEQLNSLKKENDNLKQEMSD 1117

Query: 1259 VQLSAFES--KYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADV 1316
            +Q S  E+   Y+  +  +  + +E  NK+ T+++  S+ N+  D E+        Y   
Sbjct: 1118 IQKSDNETFENYQNQIKEMMQNLEEAENKVSTLQEQISM-NEKSDSEK-----VTSYEAK 1171

Query: 1317 INQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQ 1376
            I Q+   + E+E +  A                  + + N+  K+  E+ I ++ ++ + 
Sbjct: 1172 IAQMHQEKKELEKKFTA---------------AKQIVSNNRQEKKEMEEKINSLTKQVSD 1216

Query: 1377 LKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYT------ITLTQR 1430
              +              +V   EA+  ++   L+ K SEI     + T        +T++
Sbjct: 1217 KDEELQKSKEEIESLNHKVTSNEAEKQKVAEDLQQKLSEIESLKQKLTEKENDVQKVTEQ 1276

Query: 1431 NDEFENVRQQLVEYEKRIED--LTYEKES-ELAILRLKMHENANHYETMQK-ESEIERVK 1486
            N   E+++QQ+ E EK I D   T E  S EL  L+ K  ++    E +Q    ++E++K
Sbjct: 1277 NKSIEDLKQQISEKEKVITDNQKTIENLSFELTELKQKKDDSEKDKEIIQNLTKDLEKMK 1336

Query: 1487 L--------IEELNVKITESVSLNKQ----VAELNKALEEEVAK-TNEMQTALENQEIEI 1533
                      +E+  ++   +  NKQ      E  K L EE  K T +M+    ++  + 
Sbjct: 1337 ADLDSKQKENDEIRSRLNREIEDNKQALAKAVETAKILSEENEKLTKQMEQVSSSETEKC 1396

Query: 1534 VTLNDEITNLQNMVRASSSK 1553
              L+ +I+ L++ +++S ++
Sbjct: 1397 QVLSSKISTLESRLQSSETR 1416



 Score =  171 bits (417), Expect = 1e-40
 Identities = 254/1248 (20%), Positives = 550/1248 (44%), Gaps = 114/1248 (9%)

Query: 387  SQLSSETLNQDTDKKIN--KN-----EIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXX 439
            S+L+ +TL+Q+   +I   KN     EI KL   ++  NK+  + E  IS+ +       
Sbjct: 83   SELAEKTLSQEKSLEIEYAKNKRFAQEILKLRSQLEKQNKE--NDEAKISDNEAINELIA 140

Query: 440  XXXXGKDTLIAQLQ-LEHQQHMEGPSLIHVGTNTEDV--------NEIAKVQEQLKQELN 490
                 +  L+++++ LE QQ M  P    +    +D+        +E+ +  E LK++L 
Sbjct: 141  EFNKERRELLSKIEELEKQQRMNSPDAEQISKPKDDIVDDFLQRIDELMRENESLKEQLA 200

Query: 491  DEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKT-IDNFS- 548
               K    +DL++   +        +     + +NM+      +    Q Q T I   + 
Sbjct: 201  S--KPAQSQDLLDFSSNQNNSNFNQSSNQQNSQQNMLLDLFGEQQPANQSQNTDIQRLND 258

Query: 549  KVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENL 608
            K+S   KE+    ++++ L+  + E ++++G  Q   ++ +    I+S V K   E++++
Sbjct: 259  KISQLEKELAEKDDQINELANLIEENDKKQGTQQNQNLNQNDEDAIQSLVTKYEEEIDDI 318

Query: 609  AETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSV--HLEE 666
             +        L +Q  +L   L   +   +   +++  I +  S    ++I+ +  +LEE
Sbjct: 319  KKNNQNEKENLINQINELKNSLKNKEISSENDLNEMKIIIEQTSKDYETKIQDLMTNLEE 378

Query: 667  QIDALSASKKELALVIE-NLKLDKEQLYGTIKDLENDK--EDIMN------KLQNYIQEN 717
                L+   ++L    E N KL++  +     D E +K  ++I N      KLQ  + EN
Sbjct: 379  NSQKLNEMSQKLKESEEKNQKLNEMSMLQASNDAEKEKFIKEISNLTKENEKLQTVLNEN 438

Query: 718  MDLTDKLEKMSAE--KISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIE--SELSK 773
                 + E++ AE  K++  L +I  E    +QT+     +I + +   +  E  S LS+
Sbjct: 439  EKNRTENERLVAENQKLNSDLHEIG-EVNKNLQTEIEKLTEIMKSEQNNKENEMMSLLSQ 497

Query: 774  YKSRICRLEESI-AVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELV-NRLAVLM 831
             + ++  L+  +    +++    E  + +L     EKQK   +Y  + +E+  N      
Sbjct: 498  KEEQVQALQVKLNQTNQEKEKQFEDLSQKLKQLEAEKQKLNDDYESKINEIQQNDNETFT 557

Query: 832  DHDRVVEKQLLE---IEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDL 888
            ++   +++ ++    +++ENK LQ+K  I L E  + +  LS  +Q    L E  N    
Sbjct: 558  NYQNQIKEMMINNENLQNENKSLQEK--ISLNEKSDNEKVLSLEEQ----LKESKNSISS 611

Query: 889  AESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNE 948
             + +    Q  + +LE N+   +  +   I     E+  ++   N  +++ I+  +    
Sbjct: 612  LQEQLKSSQQTIENLEKNISEKSETYNEKIKSLTDELSTIQ-NTNENLQNEIKSLQEKLS 670

Query: 949  KYEKNI-EYVTQLEAQLQEYKNNI----ENLNMNVEELNKMN--LELIDKHVQKQQTQSP 1001
              EKN  E +  LE QL+  +N +    E L+    E ++M   L L++K +   Q    
Sbjct: 671  NNEKNDNEKILNLEEQLKNSQNEVRIGQEKLSKFENEYDQMRSKLSLMEKELSTSQKMKE 730

Query: 1002 DYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENME 1061
               ++  +   K++   K  +E++++L +++NN++    +M+++YE    +  ++L  + 
Sbjct: 731  SLQKEKESLQEKISLSEKSDNEKVLSLEEQLNNSK----NMITNYEQNEKELQSQLSTLN 786

Query: 1062 EEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPM 1121
            EE+   SK+++++ +  E++    +  D+++K  +E   ++   I + + +  S+  +  
Sbjct: 787  EELS-TSKKMIETLE--EKISNNEKNGDEKVKSYEEQLNSYRNTINELQQITQSNEEKIK 843

Query: 1122 SDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQ-LET 1180
            S ++ N D            + + E+ E  +E+S  + Q   L  + Q   + + Q +E+
Sbjct: 844  SLESQNKDLQEK--------ISLSEKSESDKEKSY-EAQLNNLKQQAQNHISSLNQQIES 894

Query: 1181 LNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWK 1240
            L  E++     + E     +++++++   N+NL + V  L+  IS        ++  L +
Sbjct: 895  LKQEISSIQQNDNETFTNYQNQIKEMMINNENLQNEVQSLQEKISLNEKSDNEKVLSLEE 954

Query: 1241 QHLAQRE--ADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQE-ETNKIVTMEQVTSLQN 1297
            Q    +    ++++ E EL+ QLS    +       +++  ++   N+    E+V SL+ 
Sbjct: 955  QLNNSKNMITNYEQNEKELQSQLSTLNEELSTSKKMIETLEEKISNNEKSDNEKVLSLEE 1014

Query: 1298 KLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQ 1357
            +L++ +  + +LQE+       IE L   I ++                       T N+
Sbjct: 1015 QLKESKNSISSLQEQLKSSQQTIENLEKNISEKS---------------------ETYNE 1053

Query: 1358 SYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIY 1417
              K + ++ +  I  +N  L+                 ND E KV     QL     E  
Sbjct: 1054 KIKSLTDE-LSTIQNKNENLQNE--IKSLQEKLSNNEKNDNE-KVKLYEEQLNSLKKEND 1109

Query: 1418 QKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILR--LKMHENANHYET 1475
                E +      N+ FEN + Q+ E  + +E    E E++++ L+  + M+E ++  + 
Sbjct: 1110 NLKQEMSDIQKSDNETFENYQNQIKEMMQNLE----EAENKVSTLQEQISMNEKSDSEKV 1165

Query: 1476 MQKESEIERV-KLIEELNVKITESVSLNKQVAELNKALEEEV----AKTNEMQTALENQE 1530
               E++I ++ +  +EL  K T +  +     +  K +EE++     + ++    L+  +
Sbjct: 1166 TSYEAKIAQMHQEKKELEKKFTAAKQIVSNNRQEKKEMEEKINSLTKQVSDKDEELQKSK 1225

Query: 1531 IEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNK 1578
             EI +LN ++T+ +   +  +  +Q+ +S     KQ   E+ +N + K
Sbjct: 1226 EEIESLNHKVTSNEAEKQKVAEDLQQKLSEIESLKQKLTEK-ENDVQK 1272



 Score =  157 bits (380), Expect = 3e-36
 Identities = 235/1195 (19%), Positives = 524/1195 (43%), Gaps = 103/1195 (8%)

Query: 144  VTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXX 203
            V  L   +KE  N++S LQ ++K  + TI +L++ I+EK +    K K+ T         
Sbjct: 595  VLSLEEQLKESKNSISSLQEQLKSSQQTIENLEKNISEKSETYNEKIKSLT-------DE 647

Query: 204  XXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAA 263
                    E+ + ++  +QE     E   K++ +++L ++E + ++ S  E      + +
Sbjct: 648  LSTIQNTNENLQNEIKSLQEKLSNNE---KNDNEKIL-NLE-EQLKNSQNEVRIGQEKLS 702

Query: 264  RFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTE 323
            +FE   E+ ++  +L                L K+  + S +EK  + EK   E   +  
Sbjct: 703  KFE--NEYDQMRSKLSLMEKELSTSQKMKESLQKE--KESLQEKISLSEKSDNE--KVLS 756

Query: 324  LTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRK---SGRNTAS 380
            L +++   +++     Q  KEL+++L+T+  E     S SKK    +  K   + +N   
Sbjct: 757  LEEQLNNSKNMITNYEQNEKELQSQLSTLNEE----LSTSKKMIETLEEKISNNEKNGDE 812

Query: 381  KMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXX 440
            K+KS   QL+S     +  ++I ++   K++  ++S NKDL +K  +  + ++       
Sbjct: 813  KVKSYEEQLNSYRNTINELQQITQSNEEKIKS-LESQNKDLQEKISLSEKSESDKEKSYE 871

Query: 441  XXXGKDTLIAQLQLEH-QQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQ-ELNDEIKDVNV 498
                     AQ  +    Q +E            D       Q Q+K+  +N+E     V
Sbjct: 872  AQLNNLKQQAQNHISSLNQQIESLKQEISSIQQNDNETFTNYQNQIKEMMINNENLQNEV 931

Query: 499  KDLIEKL----KSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSN 554
            + L EK+    KS  E++  L ++++  +KNMI   +N++   K++Q  +   ++   ++
Sbjct: 932  QSLQEKISLNEKSDNEKVLSLEEQLN-NSKNMI---TNYEQNEKELQSQLSTLNEELSTS 987

Query: 555  KEIVRLTEELHHLSQKVAELEEEKGNLQLHLVD-YDSGRMIESDVYKKMIEMENLAETRL 613
            K+++   EE   +S       E+  +L+  L +  +S   ++  +      +ENL +   
Sbjct: 988  KKMIETLEE--KISNNEKSDNEKVLSLEEQLKESKNSISSLQEQLKSSQQTIENLEKNIS 1045

Query: 614  KAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHL-EEQIDALS 672
            +       +   L  EL  +Q K + +++++  + +  S+   ++ + V L EEQ+++L 
Sbjct: 1046 EKSETYNEKIKSLTDELSTIQNKNENLQNEIKSLQEKLSNNEKNDNEKVKLYEEQLNSLK 1105

Query: 673  ASKKELALVIENL-KLDK---EQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMS 728
                 L   + ++ K D    E     IK++  + E+  NK+   +QE + +    EK  
Sbjct: 1106 KENDNLKQEMSDIQKSDNETFENYQNQIKEMMQNLEEAENKVST-LQEQISMN---EKSD 1161

Query: 729  AEKISELLAKI--NHEEQSKIQTQFGIDAKIQERDLY-IENIESELSKYKSRICRLEESI 785
            +EK++   AKI   H+E+ +++ +F    +I   +    + +E +++    ++   +E +
Sbjct: 1162 SEKVTSYEAKIAQMHQEKKELEKKFTAAKQIVSNNRQEKKEMEEKINSLTKQVSDKDEEL 1221

Query: 786  AVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIE 845
               ++   SL  K   + S   EKQK   +   +  E+ +    L + +  V+K    + 
Sbjct: 1222 QKSKEEIESLNHK---VTSNEAEKQKVAEDLQQKLSEIESLKQKLTEKENDVQK----VT 1274

Query: 846  HENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLE- 904
             +NK ++   Q + E+ + +  +   ++     L E   + D +E +    Q   +DLE 
Sbjct: 1275 EQNKSIEDLKQQISEKEKVITDNQKTIENLSFELTELKQKKDDSEKDKEIIQNLTKDLEK 1334

Query: 905  --SNLKRITHEHQTLIVQKKKEIEDLEIEFNTQ-IESAIRDKKVLNEKYEKNIEYVTQLE 961
              ++L     E+  +  +  +EIED     N Q +  A+   K+L+E+ EK  + + Q+ 
Sbjct: 1335 MKADLDSKQKENDEIRSRLNREIED-----NKQALAKAVETAKILSEENEKLTKQMEQVS 1389

Query: 962  AQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQK 1021
            +   E K  + +  ++  E    + E     V + + +    + + +  +++L     +K
Sbjct: 1390 SSETE-KCQVLSSKISTLESRLQSSETRATSVLEDRNR---LSSELLRTMSELKESKNEK 1445

Query: 1022 DEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEEL 1081
            D+     N KI   + +     ++YE K+    ++  ++E ++     ++ + +++ + L
Sbjct: 1446 DKITQEFNDKIKELESNSREQTANYEGKIKLLESEKSSLETKINEDQLKISNLEKNVQNL 1505

Query: 1082 QILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXX 1141
                   D+++ +LKE          K +  I +  +E M    +N              
Sbjct: 1506 SNKNSVSDNEVSKLKEDN-------SKLKNQISNFEVEIMQIKESN-------------D 1545

Query: 1142 LKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKS 1201
            L   + E+  + ++ LQ+    L    ++   K+ Q++  + E    + +N   + + K 
Sbjct: 1546 LLTSQNEKLRESKNKLQQNVNDLEATKKDLTQKMAQMKCDSRE----NEIN--SLLETKK 1599

Query: 1202 KLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAE---LWKQHLAQRE-ADFQKTEHEL 1257
             LE+  +   N ++T+ + +S ++  ++ +  +I +    +K+ ++Q +   F+  + ++
Sbjct: 1600 SLEEKISVLQNQIATILKDKSDLAEQIELKEIDIKDQMLKYKEQMSQNDNVVFEMRKEKI 1659

Query: 1258 RVQLSAFESKYEQLLD-SVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQE 1311
             ++    E KY+  L+ S  +  +EE  K    E++     K+Q     L+ + E
Sbjct: 1660 ELENQIKEIKYQNELNVSKMNQEKEELTKSYE-EKILLYAKKVQQLSRKLQKVSE 1713



 Score =  135 bits (326), Expect = 1e-29
 Identities = 227/1044 (21%), Positives = 439/1044 (42%), Gaps = 91/1044 (8%)

Query: 97   TLKQKEI-LMEKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGD----VTHLSNTI 151
            +L +KE+   +K+K+  +  K S    +                QL +    +T+     
Sbjct: 716  SLMEKELSTSQKMKESLQKEKESLQEKISLSEKSDNEKVLSLEEQLNNSKNMITNYEQNE 775

Query: 152  KEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXX 211
            KE  + LS L  ++   +  I  L+EKI+  ++  + K K+                   
Sbjct: 776  KELQSQLSTLNEELSTSKKMIETLEEKISNNEKNGDEKVKSYEEQLNSYRNTI------- 828

Query: 212  EDTKQQMTKMQENFI-AMEAEWKDEKQRLLKDIESKDVRISSLE-EANKLLEAARFEISL 269
             +  QQ+T+  E  I ++E++ KD ++++    +S+  +  S E + N L + A+  IS 
Sbjct: 829  -NELQQITQSNEEKIKSLESQNKDLQEKISLSEKSESDKEKSYEAQLNNLKQQAQNHISS 887

Query: 270  EHSK---LAQELEQXXXXXXXXXXXXXXLAKQSI---EPSCEEKTEIEEKGSLEIANMTE 323
             + +   L QE+                  K+ +   E    E   ++EK SL   +  E
Sbjct: 888  LNQQIESLKQEISSIQQNDNETFTNYQNQIKEMMINNENLQNEVQSLQEKISLNEKSDNE 947

Query: 324  LTKKIELLEHLN------CQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRN 377
              K + L E LN          Q  KEL+++L+T+  E     S SKK    +  K   N
Sbjct: 948  --KVLSLEEQLNNSKNMITNYEQNEKELQSQLSTLNEEL----STSKKMIETLEEKISNN 1001

Query: 378  TASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXX 437
              S  +   S L  +           + ++   +  I++L K++ +K    +EK      
Sbjct: 1002 EKSDNEKVLS-LEEQLKESKNSISSLQEQLKSSQQTIENLEKNISEKSETYNEKIKSLTD 1060

Query: 438  XXXXXXGKD----TLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEI 493
                   K+      I  LQ E   + E      V    E +N + K  + LKQE++D  
Sbjct: 1061 ELSTIQNKNENLQNEIKSLQ-EKLSNNEKNDNEKVKLYEEQLNSLKKENDNLKQEMSDIQ 1119

Query: 494  KDVN---------VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTI 544
            K  N         +K++++ L+ AE +++ L ++I    K+  +  ++++ K+ QM +  
Sbjct: 1120 KSDNETFENYQNQIKEMMQNLEEAENKVSTLQEQISMNEKSDSEKVTSYEAKIAQMHQEK 1179

Query: 545  DNFSK--------VSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIES 596
                K        VS++ +E   + E+++ L+++V++ +EE   LQ    + +S   +  
Sbjct: 1180 KELEKKFTAAKQIVSNNRQEKKEMEEKINSLTKQVSDKDEE---LQKSKEEIES---LNH 1233

Query: 597  DVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVC 656
             V     E + +AE   + +S +ES K  L ++ + +Q K  E    + D+ Q  S++  
Sbjct: 1234 KVTSNEAEKQKVAEDLQQKLSEIESLKQKLTEKENDVQ-KVTEQNKSIEDLKQQISEK-- 1290

Query: 657  SEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQE 716
             E      ++ I+ LS    EL    ++ + DKE +    KDLE  K D+ +K +   + 
Sbjct: 1291 -EKVITDNQKTIENLSFELTELKQKKDDSEKDKEIIQNLTKDLEKMKADLDSKQKENDEI 1349

Query: 717  NMDLTDKLE--KMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKY 774
               L  ++E  K +  K  E  AKI  EE  K+  Q    +  +     +  + S++S  
Sbjct: 1350 RSRLNREIEDNKQALAKAVET-AKILSEENEKLTKQMEQVSSSETEKCQV--LSSKISTL 1406

Query: 775  KSRICRLE-ESIAVMEDR-RYSLE--RKADQLGSYLQEKQKAYSEYTIQEDELVN----R 826
            +SR+   E  + +V+EDR R S E  R   +L     EK K   E+  +  EL +    +
Sbjct: 1407 ESRLQSSETRATSVLEDRNRLSSELLRTMSELKESKNEKDKITQEFNDKIKELESNSREQ 1466

Query: 827  LAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRT 886
             A      +++E +   +E +  E Q K   L +  QNL    S      + L E  ++ 
Sbjct: 1467 TANYEGKIKLLESEKSSLETKINEDQLKISNLEKNVQNLSNKNSVSDNEVSKLKEDNSKL 1526

Query: 887  DLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKK---EIEDLEIEFNTQIESAIRDK 943
               +++ + ++ ++  ++ +   +T +++ L   K K    + DLE      +   +   
Sbjct: 1527 ---KNQISNFEVEIMQIKESNDLLTSQNEKLRESKNKLQQNVNDLEAT-KKDLTQKMAQM 1582

Query: 944  KVLNEKYEKN--IEYVTQLEAQLQEYKNNIENLNMNVEEL-NKMNLELID-KHVQKQQTQ 999
            K  + + E N  +E    LE ++   +N I  +  +  +L  ++ L+ ID K    +  +
Sbjct: 1583 KCDSRENEINSLLETKKSLEEKISVLQNQIATILKDKSDLAEQIELKEIDIKDQMLKYKE 1642

Query: 1000 SPDYTEQYINEINKLNALLKQKDEEIIALNQ-KINNAQVSYMSMVSDYESKLAQFTTKLE 1058
                 +  + E+ K    L+ + +EI   N+  ++        +   YE K+  +  K++
Sbjct: 1643 QMSQNDNVVFEMRKEKIELENQIKEIKYQNELNVSKMNQEKEELTKSYEEKILLYAKKVQ 1702

Query: 1059 NMEEEMQRVSKQLLDSKQHNEELQ 1082
             +  ++Q+VS+     K    E Q
Sbjct: 1703 QLSRKLQKVSENQSPQKPKPAETQ 1726



 Score =  123 bits (296), Expect = 5e-26
 Identities = 178/874 (20%), Positives = 383/874 (43%), Gaps = 66/874 (7%)

Query: 730  EKISELLAKINHEEQSKIQTQFGIDAKIQERDLY--IENIESELSKYKSRICRLEESIAV 787
            +KI E   K   E   + + +F  +A  + +D+Y   +N E ++S+   +    E+S+ +
Sbjct: 40   QKILEDAVKQRDEIIGQAEQKFK-EAASKYQDVYQKYQNNEKQISELAEKTLSQEKSLEI 98

Query: 788  MEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHE 847
               +     ++  +L S L+++ K   E  I ++E +N L    + +R   ++LL    E
Sbjct: 99   EYAKNKRFAQEILKLRSQLEKQNKENDEAKISDNEAINELIAEFNKER---RELLSKIEE 155

Query: 848  NKELQKKNQILLEENQNLQISL-SDMQQHYNALVEKANRTDLAESESTKYQTQ-LRDLES 905
             ++ Q+ N    E+    +  +  D  Q  + L+ + N +   +  S   Q+Q L D  S
Sbjct: 156  LEKQQRMNSPDAEQISKPKDDIVDDFLQRIDELMRE-NESLKEQLASKPAQSQDLLDFSS 214

Query: 906  NLKRITHEHQTLIVQKKKE--IEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQ 963
            N    ++ +Q+   Q  ++  + DL  E     +S   D + LN+K  +  + + + + Q
Sbjct: 215  NQNN-SNFNQSSNQQNSQQNMLLDLFGEQQPANQSQNTDIQRLNDKISQLEKELAEKDDQ 273

Query: 964  LQEYKNNIE------------NLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEI 1011
            + E  N IE            NLN N E+  +  +   ++ +   +  + +  E  IN+I
Sbjct: 274  INELANLIEENDKKQGTQQNQNLNQNDEDAIQSLVTKYEEEIDDIKKNNQNEKENLINQI 333

Query: 1012 NKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQL 1071
            N+L   LK K+   I+    +N  ++       DYE+K+    T LE   +++  +S++L
Sbjct: 334  NELKNSLKNKE---ISSENDLNEMKIIIEQTSKDYETKIQDLMTNLEENSQKLNEMSQKL 390

Query: 1072 LDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXX 1131
             +S++ N++L  +   Q     E KE  +    N+ K E   + + +    ++ N  +  
Sbjct: 391  KESEEKNQKLNEMSMLQASNDAE-KEKFIKEISNLTK-ENEKLQTVLN--ENEKNRTENE 446

Query: 1132 XXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVV 1191
                        V E ++   +   + E +  L TE+++  T+I++ E  N E     ++
Sbjct: 447  RL----------VAENQKLNSDLHEIGEVNKNLQTEIEKL-TEIMKSEQNNKENEMMSLL 495

Query: 1192 NQ--EQINQLKSKLEQLNTEND----NLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQ 1245
            +Q  EQ+  L+ KL Q N E +    +L   + +L +      D    +I E+ +Q+  +
Sbjct: 496  SQKEEQVQALQVKLNQTNQEKEKQFEDLSQKLKQLEAEKQKLNDDYESKINEI-QQNDNE 554

Query: 1246 READFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTME-QVTSLQNKLQDKEE 1304
               ++Q    E+ +     +++ + L + +  + + +  K++++E Q+   +N +   +E
Sbjct: 555  TFTNYQNQIKEMMINNENLQNENKSLQEKISLNEKSDNEKVLSLEEQLKESKNSISSLQE 614

Query: 1305 HLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQE 1364
             L++ Q+   ++   I   +SE  +EK+                  +L+ E +S ++   
Sbjct: 615  QLKSSQQTIENLEKNISE-KSETYNEKIK---SLTDELSTIQNTNENLQNEIKSLQEKLS 670

Query: 1365 QSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYT 1424
             +  N NE+   L++              +++  E +  ++  +L L + E+   T +  
Sbjct: 671  NNEKNDNEKILNLEEQLKNSQNEVRIGQEKLSKFENEYDQMRSKLSLMEKEL--STSQKM 728

Query: 1425 ITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIER 1484
                Q+  E E++++++   EK   +     E +L            +YE  +KE + + 
Sbjct: 729  KESLQK--EKESLQEKISLSEKSDNEKVLSLEEQLN----NSKNMITNYEQNEKELQSQL 782

Query: 1485 VKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALEN--QEIEIVTLNDE--I 1540
              L EEL+       +L ++++   K  +E+V    E   +  N   E++ +T ++E  I
Sbjct: 783  STLNEELSTSKKMIETLEEKISNNEKNGDEKVKSYEEQLNSYRNTINELQQITQSNEEKI 842

Query: 1541 TNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDN 1574
             +L++  +    KI       SD ++  + QL+N
Sbjct: 843  KSLESQNKDLQEKISLSEKSESDKEKSYEAQLNN 876



 Score =  104 bits (249), Expect = 2e-20
 Identities = 165/856 (19%), Positives = 359/856 (41%), Gaps = 67/856 (7%)

Query: 749  TQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQE 808
            T   +  K  +  +  +  + ++ KY      LE+++   ++     E+K  +  S  Q+
Sbjct: 11   TSSELKEKYNQLAIKYKKAKEDIDKYSHNQKILEDAVKQRDEIIGQAEQKFKEAASKYQD 70

Query: 809  KQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQK-KNQILLEENQNLQI 867
                Y +Y   E ++       +  ++ +E +  + +   +E+ K ++Q+  +  +N + 
Sbjct: 71   ---VYQKYQNNEKQISELAEKTLSQEKSLEIEYAKNKRFAQEILKLRSQLEKQNKENDEA 127

Query: 868  SLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIED 927
             +SD  +  N L+ + N+      E  +  +++ +LE   +R+       I + K +I D
Sbjct: 128  KISD-NEAINELIAEFNK------ERRELLSKIEELEKQ-QRMNSPDAEQISKPKDDIVD 179

Query: 928  LEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLE 987
               +F  +I+  +R+ + L E+          L       +NN  N N +  + N     
Sbjct: 180  ---DFLQRIDELMRENESLKEQLASKPAQSQDL-LDFSSNQNN-SNFNQSSNQQNSQQNM 234

Query: 988  LIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYE 1047
            L+D   ++Q       T     +I +LN  + Q ++E+   + +IN  +++ +   +D +
Sbjct: 235  LLDLFGEQQPANQSQNT-----DIQRLNDKISQLEKELAEKDDQIN--ELANLIEENDKK 287

Query: 1048 SKLAQFTTKLENMEEEMQ----RVSKQLLDSKQHNE-ELQILVREQDDQIKELKETKLTF 1102
                Q     +N E+ +Q    +  +++ D K++N+ E + L+ + ++    LK  +++ 
Sbjct: 288  QGTQQNQNLNQNDEDAIQSLVTKYEEEIDDIKKNNQNEKENLINQINELKNSLKNKEISS 347

Query: 1103 EMNIPKTEGMIISSTIE----PMSDDANNVDXXXXXXXXXXXXLKVQEEE-EFIQERSVL 1157
            E ++ + + +II  T +     + D   N++            LK  EE+ + + E S+L
Sbjct: 348  ENDLNEMK-IIIEQTSKDYETKIQDLMTNLEENSQKLNEMSQKLKESEEKNQKLNEMSML 406

Query: 1158 Q----EQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQI--NQ-LKSKLEQLNTEN 1210
            Q     +  K   E+     +  +L+T+  E   +   N+  +  NQ L S L ++   N
Sbjct: 407  QASNDAEKEKFIKEISNLTKENEKLQTVLNENEKNRTENERLVAENQKLNSDLHEIGEVN 466

Query: 1211 DNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREA---DFQKTEHELRVQLSAFESK 1267
             NL + + +L   + S  + +  E+  L  Q   Q +A      +T  E   Q      K
Sbjct: 467  KNLQTEIEKLTEIMKSEQNNKENEMMSLLSQKEEQVQALQVKLNQTNQEKEKQFEDLSQK 526

Query: 1268 YEQLLDSVQSSTQEETNKIVTMEQ-----VTSLQNKLQDKEEHLRNLQEKYADVINQIEI 1322
             +QL    Q    +  +KI  ++Q      T+ QN++++   +  NLQ +   +  +I  
Sbjct: 527  LKQLEAEKQKLNDDYESKINEIQQNDNETFTNYQNQIKEMMINNENLQNENKSLQEKIS- 585

Query: 1323 LRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSX 1382
            L  + ++EKV                   L+ + +S +Q  E    NI+E++    +   
Sbjct: 586  LNEKSDNEKV---LSLEEQLKESKNSISSLQEQLKSSQQTIENLEKNISEKSETYNEKIK 642

Query: 1383 XXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLV 1442
                          + + ++  L  +L   +    +K       L    +E    +++L 
Sbjct: 643  SLTDELSTIQNTNENLQNEIKSLQEKLSNNEKNDNEKILNLEEQLKNSQNEVRIGQEKLS 702

Query: 1443 EYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLN 1502
            ++E   + +     S+L+++  ++  +    E++QKE E  + K      + ++E  S N
Sbjct: 703  KFENEYDQM----RSKLSLMEKELSTSQKMKESLQKEKESLQEK------ISLSEK-SDN 751

Query: 1503 KQVAELNKALEEEVAK-TNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFA 1561
            ++V  L + L       TN  Q   E Q  ++ TLN+E++  + M+     KI  +    
Sbjct: 752  EKVLSLEEQLNNSKNMITNYEQNEKELQS-QLSTLNEELSTSKKMIETLEEKISNNEKNG 810

Query: 1562 SDTKQGRDEQLDNTMN 1577
             +  +  +EQL++  N
Sbjct: 811  DEKVKSYEEQLNSYRN 826


>UniRef50_Q23DH8 Cluster: DNA-directed RNA polymerase, omega subunit
            family protein; n=1; Tetrahymena thermophila SB210|Rep:
            DNA-directed RNA polymerase, omega subunit family protein
            - Tetrahymena thermophila SB210
          Length = 4331

 Score =  196 bits (478), Expect = 4e-48
 Identities = 300/1466 (20%), Positives = 636/1466 (43%), Gaps = 125/1466 (8%)

Query: 143  DVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXX 202
            ++  L+  IK K+  ++ L  ++K +E  +  L  +I +KD  +E KN+           
Sbjct: 1896 EINELNEQIKLKNEQINKLDEQIKQLEEVLNQLNSQIKQKDLDLEYKNQLFDNLKLQYEE 1955

Query: 203  XXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEA 262
                     E  K    K+ E    +E     E Q+L+  + ++ +  S  E ++ L E 
Sbjct: 1956 QGQLLHNHQEKLKSNTIKLDEQNSMIE-----ENQQLISQLRTQ-LENSLKENSHSLNEQ 2009

Query: 263  ARF--EISLEHSKLAQELEQXXXXXXXXXXXXXXL---AKQSIEPSCEEKTEIEEKGSLE 317
                 +++ E  ++ Q+ +Q              L    KQ +    E +  I+EK  + 
Sbjct: 2010 ENSINQLNCELLQMGQDKQQLQGLIHQLKEENSNLNEDLKQKLNIISESQQLIKEKSDIA 2069

Query: 318  IANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRN 377
                  LT +++  +     I+Q  +EL+        ES+ ++         +  +  +N
Sbjct: 2070 EELKQNLTNQLQKQQEYIQSIQQLQEELK--------ESQELNEKHINKIKQLEEQLQQN 2121

Query: 378  T--ASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDL---VDKEYVISEKD 432
            T     ++    +L S+    + + K  +++I + + +I+S  +     +D E  +  + 
Sbjct: 2122 TEKIDNLEENIQKLISDKEQFEINNKQLQDQINQQDQLIESFEEQFQKQLDSESKLKLQA 2181

Query: 433  TXXXXXXXXXXGKDTLIAQ--LQLEHQQHMEGPSLIH-VGTNTEDVNEIAKVQEQLKQEL 489
            T           K+ L+ Q   Q    ++ E  SL+  +  N E++  +    EQ+K+  
Sbjct: 2182 TNLEESLKEAQQKEILLEQNLTQQLESKNSEIDSLVQKIKQNEEEIVVLNNNLEQIKESH 2241

Query: 490  NDEIKDV-NVKDLIEK----LKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTI 544
            N+  + + N + L+++    L S+++ + QL   ++  N         ++ K+KQ+   +
Sbjct: 2242 NEITQKLENTEQLLKQSEQDLNSSQKLVEQLEQNLEKINSENTHAIQEYEEKIKQLNSQV 2301

Query: 545  DNFSKVSDS-----------NKEIVRLTEELHHLSQKVAELEEEKGNL---QLHLVD-YD 589
            ++ +   DS           N++I    + L    +   E E+++  L   + +L+D  +
Sbjct: 2302 ESLNNEKDSLASQFMDSDAQNQDIQLKLQSLQTELESKIEKEKQQAALIKEKQNLIDEKE 2361

Query: 590  SGRMIESDVYKKMIEMENLAETRLK-AISLLESQKFDLVQELHILQQKYDEVEDKLADIS 648
                + S  Y++  E       +L+  +  LE +    ++EL I  ++  E+++KL D+ 
Sbjct: 2362 QAIQLLSTEYEQREEQSQQVNKQLQHKLEALEERLTSKIEELKIQNEQNQELQNKLEDLI 2421

Query: 649  QLQSDQVCSEIKSVH---LEEQ----IDALSASKKELALVIENLKLDKEQLYGTIKDLEN 701
            Q ++ Q   +I   H   L+E+     + L   ++E   ++ +   +K++    +K ++ 
Sbjct: 2422 Q-ETQQKIEKINDQHQLGLQEKDNYYQELLKQKEQEQMNLLNDQLSEKQKQEEFMKCMQQ 2480

Query: 702  DKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERD 761
             ++    +LQ   Q   DL  + E    E IS     +   +Q +I  +  I  +++E+ 
Sbjct: 2481 QEQRFQEQLQITQQNAQDLVQQKEIHYKEIISMKDEDLMKRKQ-EIHEKEEIKQQLEEK- 2538

Query: 762  LYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTI--- 818
              I N+++EL   K  I +    I   ED + SL ++ D+L   LQE  +   E  +   
Sbjct: 2539 --IFNLQNELQNLKEEILQKNNDIHRQEDIQISLNKQIDELKKNLQESLQKQEESALILL 2596

Query: 819  -QEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYN 877
             +E+ +  +    +  ++ ++ QL     EN++ Q +  ++L++ +++     +     N
Sbjct: 2597 ERENNIKQQEQAQVSQNKEID-QLKNKLQENEQKQNEMALILQDKEHVMKEQEEKLISLN 2655

Query: 878  ALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIE 937
              +   N T L E+     +  L  LE   K I+ E Q  IVQ + +I   E++  TQ++
Sbjct: 2656 NEINNLNNT-LKENLQKVSERDLVLLEKE-KDIS-ELQEQIVQLQDKISSSELQI-TQLQ 2711

Query: 938  S-AIRDKKVLNEKY-------EKNIEYVTQLEAQLQEYKNNIENL-NMNVEEL--NKMNL 986
            S +I  ++ LN K        +  ++ +  L+ Q+QE + +I++L  + + EL   K N 
Sbjct: 2712 SNSINKEEELNSKLAQQASDNQNQLKLIEDLKNQIQELEKSIDSLEQLKINELQDQKNNY 2771

Query: 987  ELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDY 1046
            EL  K+ +++  +     + Y  +I + + ++++ + +I +  Q++   ++     +SD+
Sbjct: 2772 ELSIKNFEEEIKK---IKQDYETKIQENSQIIEELNVQIKSFEQQLELQKIQNKQQLSDH 2828

Query: 1047 ESKLAQFTTKLENMEEEMQ-----RVSKQLLDSKQ-HNEELQILVREQDDQIKELKETKL 1100
            E  + Q   +  N + E+Q     +      + +Q HN+++  +  E +++ K +K+   
Sbjct: 2829 EEYVKQLQEEFNNKKLELQKEYETKAGASFSEIEQLHNQKINKMQEEFEEKHKNMKD--- 2885

Query: 1101 TFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQ 1160
            + +  I K     +   +E    +   ++             K +++++  QE     ++
Sbjct: 2886 SLQSEIKK-----LQEDLEAQIQENKKLNLQIQELDSELLNAK-EQKQKISQEVDETLQK 2939

Query: 1161 SAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAEL 1220
            + +LN ++Q+   +I Q+  L ++       +Q++IN L+ K E+   E         +L
Sbjct: 2940 NVELNDKIQQ---QIEQINNLLSKQNEERQSHQDEINLLQEKFEKQLEEVQK--QNQVKL 2994

Query: 1221 RSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQ 1280
              S S        EI +L +    Q+EA   K ++EL  QLS  + + + L   +++   
Sbjct: 2995 EQSHSEVEQSHQSEIQQLLQN---QQEA-ILKLKNELTEQLSKVQQENDLLEKQLRAKES 3050

Query: 1281 EETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQI---EILRSEIEDEKVAFXXX 1337
            EE       ++++   +++Q+KE  L +L+E+   +I ++   E +++E+ +E       
Sbjct: 3051 EEEQ---LNDKLSQQYDQIQEKESDLVSLKEENNKLIQKVQNFEKIKNELVEENNQLKQN 3107

Query: 1338 XXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVND 1397
                         +L    Q   Q +EQ I + N +N Q K+S                 
Sbjct: 3108 IVELENSSAEISANLEKLIQE-NQDKEQQIYDFN-DNLQQKESQIQELNSKILQIEEKYQ 3165

Query: 1398 AEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKES 1457
             + + LE  HQ+++KD        E T+ L ++  +F+     L E +  +E   YE   
Sbjct: 3166 TQIQELEKNHQVKIKDLADKFTVCEDTLVLQEK--QFQEKLSNLQE-KYNLEQTNYE--- 3219

Query: 1458 ELAILRLKMHENAN-HYETMQKESEIERV---KLIEELNVKITESVSLNKQVAELNKALE 1513
             L I    +    N   E +QK+ E   +   K  EE ++    S +L +Q  +L+K  E
Sbjct: 3220 SLQIDHQNIQSQLNLLQEELQKQIEGNHILSQKQQEEKDLVSENSQNLQQQNLDLHKENE 3279

Query: 1514 EEVAKTNEMQTALENQEIEIVTLNDE 1539
            E  AK  +M+  L   E +I  +ND+
Sbjct: 3280 ESKAKIQQMKEKLSQLEEQIEKVNDD 3305



 Score =  196 bits (477), Expect = 6e-48
 Identities = 305/1505 (20%), Positives = 656/1505 (43%), Gaps = 126/1505 (8%)

Query: 154  KDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXED 213
            K N  + LQ + + +++ I  LQE++ E  ++ E K+                     E+
Sbjct: 2073 KQNLTNQLQKQQEYIQS-IQQLQEELKESQELNE-KHINKIKQLEEQLQQNTEKIDNLEE 2130

Query: 214  TKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISS-LEEANKL-LEAARFEISLEH 271
              Q++   +E F     + +D+  +  + IES + +    L+  +KL L+A   E SL+ 
Sbjct: 2131 NIQKLISDKEQFEINNKQLQDQINQQDQLIESFEEQFQKQLDSESKLKLQATNLEESLKE 2190

Query: 272  SKLAQEL-EQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIEL 330
            ++  + L EQ                 Q I+ + EE   +         +  E+T+K+E 
Sbjct: 2191 AQQKEILLEQNLTQQLESKNSEIDSLVQKIKQNEEEIVVLNNNLEQIKESHNEITQKLEN 2250

Query: 331  LEHLNCQIRQTN-------KELENKLATMGTESK-AVSSPSKKGSPLISR-KSGRNTASK 381
             E L  Q  Q         ++LE  L  + +E+  A+    +K   L S+ +S  N    
Sbjct: 2251 TEQLLKQSEQDLNSSQKLVEQLEQNLEKINSENTHAIQEYEEKIKQLNSQVESLNNEKDS 2310

Query: 382  MKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKD---LVDKEYVISEKDTXXXXX 438
            + S +  + S+  NQD   K+   +  +LE  I+   +    + +K+ +I EK+      
Sbjct: 2311 LASQF--MDSDAQNQDIQLKLQSLQ-TELESKIEKEKQQAALIKEKQNLIDEKEQAIQLL 2367

Query: 439  XXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNV 498
                  ++    Q+  + Q  +E          T  + E+ K+Q +  QEL ++++D+ +
Sbjct: 2368 STEYEQREEQSQQVNKQLQHKLEALE----ERLTSKIEEL-KIQNEQNQELQNKLEDL-I 2421

Query: 499  KDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKL-----KLKQMQKTIDNFSKVSDS 553
            ++  +K++   +Q      E D   + ++K K   ++     +L + QK  + F K    
Sbjct: 2422 QETQQKIEKINDQHQLGLQEKDNYYQELLKQKEQEQMNLLNDQLSEKQKQ-EEFMKCMQQ 2480

Query: 554  NKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRL 613
             ++  R  E+L    Q   +L ++K   ++H  +  S  M + D+ K+  E+    E + 
Sbjct: 2481 QEQ--RFQEQLQITQQNAQDLVQQK---EIHYKEIIS--MKDEDLMKRKQEIHEKEEIKQ 2533

Query: 614  KAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSA 673
            +    LE + F+L  EL  L++   E+  K  DI + +  Q+    +   L++ +     
Sbjct: 2534 Q----LEEKIFNLQNELQNLKE---EILQKNNDIHRQEDIQISLNKQIDELKKNLQESLQ 2586

Query: 674  SKKELALVI----ENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSA 729
             ++E AL++     N+K  ++      K+++  K  +    Q   +  + L DK   M  
Sbjct: 2587 KQEESALILLERENNIKQQEQAQVSQNKEIDQLKNKLQENEQKQNEMALILQDKEHVMKE 2646

Query: 730  EKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVME 789
            ++  E L  +N+E  +   T      K+ ERDL +   E ++S+       L+E I  ++
Sbjct: 2647 QE--EKLISLNNEINNLNNTLKENLQKVSERDLVLLEKEKDISE-------LQEQIVQLQ 2697

Query: 790  DRRYSLERKADQLGSY-LQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHEN 848
            D+  S E +  QL S  + ++++  S+   Q  +  N+L ++ D    ++ Q+ E+E   
Sbjct: 2698 DKISSSELQITQLQSNSINKEEELNSKLAQQASDNQNQLKLIED----LKNQIQELEKSI 2753

Query: 849  KELQK-KNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNL 907
              L++ K   L ++  N ++S+ + ++     +++   T + E+        + +L   +
Sbjct: 2754 DSLEQLKINELQDQKNNYELSIKNFEEEIKK-IKQDYETKIQENSQI-----IEELNVQI 2807

Query: 908  KRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEY 967
            K    + +   +Q K+++ D E E+  Q++    +KK+  +K     EY T+  A   E 
Sbjct: 2808 KSFEQQLELQKIQNKQQLSDHE-EYVKQLQEEFNNKKLELQK-----EYETKAGASFSE- 2860

Query: 968  KNNIENLNMNVEELNKMNLELIDKH------VQKQQTQSPDYTEQYINEINKLNALLKQK 1021
               IE L+   +++NKM  E  +KH      +Q +  +  +  E  I E  KLN  +++ 
Sbjct: 2861 ---IEQLHN--QKINKMQEEFEEKHKNMKDSLQSEIKKLQEDLEAQIQENKKLNLQIQEL 2915

Query: 1022 DEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRV-SKQLLDSKQHNEE 1080
            D E+  LN K    ++S    V +   K  +   K++   E++  + SKQ  + + H +E
Sbjct: 2916 DSEL--LNAKEQKQKIS--QEVDETLQKNVELNDKIQQQIEQINNLLSKQNEERQSHQDE 2971

Query: 1081 LQILVREQDDQIKEL-KETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXX 1139
            + +L  + + Q++E+ K+ ++  E +  + E    S   + + +    +           
Sbjct: 2972 INLLQEKFEKQLEEVQKQNQVKLEQSHSEVEQSHQSEIQQLLQNQQEAI--LKLKNELTE 3029

Query: 1140 XXLKVQEEEEFIQERSVLQE-QSAKLNTELQECYTKI-------IQLETLNTELTGHDVV 1191
               KVQ+E + ++++   +E +  +LN +L + Y +I       + L+  N +L    V 
Sbjct: 3030 QLSKVQQENDLLEKQLRAKESEEEQLNDKLSQQYDQIQEKESDLVSLKEENNKLI-QKVQ 3088

Query: 1192 NQEQI-NQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELW--KQHLAQREA 1248
            N E+I N+L  +  QL      L ++ AE+ +++   + +   +  +++    +L Q+E+
Sbjct: 3089 NFEKIKNELVEENNQLKQNIVELENSSAEISANLEKLIQENQDKEQQIYDFNDNLQQKES 3148

Query: 1249 DFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRN 1308
              Q+   ++      ++++ ++L  + Q   ++  +K    E    LQ K    +E L N
Sbjct: 3149 QIQELNSKILQIEEKYQTQIQELEKNHQVKIKDLADKFTVCEDTLVLQEK--QFQEKLSN 3206

Query: 1309 LQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSY-KQMQEQSI 1367
            LQEKY   + Q      +I+ + +                   + ++ Q   K +  ++ 
Sbjct: 3207 LQEKYN--LEQTNYESLQIDHQNIQSQLNLLQEELQKQIEGNHILSQKQQEEKDLVSENS 3264

Query: 1368 LNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITL 1427
             N+ ++N  L K +            +++  E ++ ++    +    E  +   E    +
Sbjct: 3265 QNLQQQNLDLHKENEESKAKIQQMKEKLSQLEEQIEKVNDDKQKSQEENEKMRIEKETEI 3324

Query: 1428 TQRNDEFENVRQQLVEYEKRIEDLTYE-KESELAILRLKMHENANHYETMQKESEIERVK 1486
             ++  E + ++ Q+ + E  +E+ T + + + + + + K   +  + +    E  +++++
Sbjct: 3325 EEKEKEIQKLKVQIQDLEGVMEEQTQQIQTANVEVEKFKKDLDERYNQIAFLEDILKQLE 3384

Query: 1487 LIEELNVKITESVSLNKQVAELNK--ALEEEVAKTNEMQTALE---NQEIEIVT-LNDEI 1540
              E+ N++ T +   N  + E N+   +EE +   N+  T L+      +EI+  L  ++
Sbjct: 3385 E-EKNNLQNTLNECDNALIQERNERATVEETINLLNDKITNLQIEREDNLEIIEKLKADL 3443

Query: 1541 TNLQNMVRASSS-KIQ-KHVSFASDTKQGRDEQLDNTM--NKELLDAVPRAELDLAMYML 1596
               Q   + SS  K+     S  + +   + +Q+D     N ELLD +   EL++  Y  
Sbjct: 3444 LQSQPQKQNSSPIKLSLPQTSSQAGSSSAQKQQIDQLTFANAELLDQINELELEIKEYQR 3503

Query: 1597 HQRDV 1601
             + ++
Sbjct: 3504 EKEEI 3508



 Score =  193 bits (471), Expect = 3e-47
 Identities = 294/1456 (20%), Positives = 641/1456 (44%), Gaps = 141/1456 (9%)

Query: 166  KIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENF 225
            KI +   L LQEK N   ++++ K +                    +  +QQ  + QE  
Sbjct: 2430 KINDQHQLGLQEKDNYYQELLKQKEQEQMNLLNDQLSEKQKQEEFMKCMQQQEQRFQEQL 2489

Query: 226  IAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXX 285
               +   +D  Q+  K+I  K++ IS  +E    L   + EI  E  ++ Q+LE+     
Sbjct: 2490 QITQQNAQDLVQQ--KEIHYKEI-ISMKDED---LMKRKQEIH-EKEEIKQQLEEKIFNL 2542

Query: 286  XXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKEL 345
                       K+ I    ++  +I  +  ++I+    L K+I+ L+  N Q     K+ 
Sbjct: 2543 QNELQNL----KEEI---LQKNNDIHRQEDIQIS----LNKQIDELKK-NLQ-ESLQKQE 2589

Query: 346  ENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKN 405
            E+ L  +  E+        + S        +N   + +   ++++    +++   K  + 
Sbjct: 2590 ESALILLERENNIKQQEQAQVSQNKEIDQLKNKLQENEQKQNEMALILQDKEHVMKEQEE 2649

Query: 406  EIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSL 465
            ++  L   I +LN  L +    +SE+D                I QLQ      +    L
Sbjct: 2650 KLISLNNEINNLNNTLKENLQKVSERDLVLLEKEKDISELQEQIVQLQ----DKISSSEL 2705

Query: 466  IHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKN 525
                  +  +N+  ++  +L Q+ +D   + N   LIE LK+  +++ +  D ++    N
Sbjct: 2706 QITQLQSNSINKEEELNSKLAQQASD---NQNQLKLIEDLKNQIQELEKSIDSLEQLKIN 2762

Query: 526  MIK-VKSNHKLKLKQMQKTIDNFSKVSDSN-KEIVRLTEELH-HLSQKVAELEEEKGNLQ 582
             ++  K+N++L +K  ++ I    +  ++  +E  ++ EEL+  +     +LE +K   +
Sbjct: 2763 ELQDQKNNYELSIKNFEEEIKKIKQDYETKIQENSQIIEELNVQIKSFEQQLELQKIQNK 2822

Query: 583  LHLVDYDSG-RMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVE 641
              L D++   + ++ +   K +E++   ET+  A        F  +++LH   QK ++++
Sbjct: 2823 QQLSDHEEYVKQLQEEFNNKKLELQKEYETKAGA-------SFSEIEQLH--NQKINKMQ 2873

Query: 642  DKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLEN 701
            ++  +  +   D + SEIK   L+E ++A     K+L L I+  +LD E L     + + 
Sbjct: 2874 EEFEEKHKNMKDSLQSEIKK--LQEDLEAQIQENKKLNLQIQ--ELDSELL-----NAKE 2924

Query: 702  DKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSK------IQTQFG--I 753
             K+ I  ++   +Q+N++L DK+++   E+I+ LL+K N E QS       +Q +F   +
Sbjct: 2925 QKQKISQEVDETLQKNVELNDKIQQQ-IEQINNLLSKQNEERQSHQDEINLLQEKFEKQL 2983

Query: 754  DAKIQERDLYIENIESELSK-YKSRICRL----EESIAVMEDRRYSLERKADQLGSYLQE 808
            +   ++  + +E   SE+ + ++S I +L    +E+I  +++       K  Q    L++
Sbjct: 2984 EEVQKQNQVKLEQSHSEVEQSHQSEIQQLLQNQQEAILKLKNELTEQLSKVQQENDLLEK 3043

Query: 809  KQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQI-------LLEE 861
            + +A      +E++L ++L+   D  +  E  L+ ++ EN +L +K Q        L+EE
Sbjct: 3044 QLRAKES---EEEQLNDKLSQQYDQIQEKESDLVSLKEENNKLIQKVQNFEKIKNELVEE 3100

Query: 862  NQNLQISLSDMQQHYNALVE-KANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQ 920
            N  L+ ++ +++   N+  E  AN   L +    K Q Q+ D   NL+    + ++ I +
Sbjct: 3101 NNQLKQNIVELE---NSSAEISANLEKLIQENQDKEQ-QIYDFNDNLQ----QKESQIQE 3152

Query: 921  KKKEIEDLEIEFNTQIESAIRDKKV----LNEKYEKNIEYVTQLEAQLQEYKNNIENLNM 976
               +I  +E ++ TQI+   ++ +V    L +K+    + +   E Q QE  +N++    
Sbjct: 3153 LNSKILQIEEKYQTQIQELEKNHQVKIKDLADKFTVCEDTLVLQEKQFQEKLSNLQE-KY 3211

Query: 977  NVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALN-QKINNA 1035
            N+E+ N  +L++  +++Q Q     +  ++ I E N + +  +Q+++++++ N Q +   
Sbjct: 3212 NLEQTNYESLQIDHQNIQSQLNLLQEELQKQI-EGNHILSQKQQEEKDLVSENSQNLQQQ 3270

Query: 1036 QVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKEL 1095
             +       + ++K+ Q   KL  +EE++++V+     S++ NE+++I   E++ +I+E 
Sbjct: 3271 NLDLHKENEESKAKIQQMKEKLSQLEEQIEKVNDDKQKSQEENEKMRI---EKETEIEEK 3327

Query: 1096 KETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERS 1155
            ++     ++ I   EG++   T +  +    NV+             ++   E+ +++  
Sbjct: 3328 EKEIQKLKVQIQDLEGVMEEQTQQIQTA---NVEVEKFKKDLDERYNQIAFLEDILKQ-- 3382

Query: 1156 VLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLS 1215
             L+E+   L   L EC   +IQ       +       +E IN L  K+  L  E ++ L 
Sbjct: 3383 -LEEEKNNLQNTLNECDNALIQERNERATV-------EETINLLNDKITNLQIEREDNLE 3434

Query: 1216 TVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSV 1275
             + +L++ +  +  Q+  + +   K  L Q  +    +  + + Q+        +LLD +
Sbjct: 3435 IIEKLKADLLQSQPQK--QNSSPIKLSLPQTSSQAGSSSAQ-KQQIDQLTFANAELLDQI 3491

Query: 1276 QSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFX 1335
                 E        E++    +KL  + E L+ LQ +   V  ++E+    IED ++   
Sbjct: 3492 NELELEIKEYQREKEEILDENDKLTKEIELLKGLQGEQP-VNRKVEL----IEDREIM-- 3544

Query: 1336 XXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRV 1395
                           +L+  NQ  +Q+Q+Q   ++  E + LK                +
Sbjct: 3545 -------------EQELQQLNQE-QQVQKQKRASLQNEMSDLKSILEQNIVVIQTLEEEI 3590

Query: 1396 NDAEAKVLELTHQLELKDSEIYQKTHEYTIT---LTQRNDEFENVRQQLVEYEKRIEDLT 1452
             + + K+ E    L+LK     Q +  ++     L     E +N++ Q+ + E+++ +  
Sbjct: 3591 VNYKKKLAEKEESLQLKQVANDQNSERFSKIEEELDISKHENQNLKNQITQLEQQLSEKD 3650

Query: 1453 YEKES------ELAILRLKMHENANHYETMQ--KESEIERVK-LIEELNVKITESVSLNK 1503
            Y  E       EL+ +  K     +  E ++  K+   +++K L++E N  +       K
Sbjct: 3651 YHLEQQHNSICELSAMIEKFENQKSDAEVIENLKQMHTDKMKKLVKEHNEALASKDKEIK 3710

Query: 1504 QVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASD 1563
            Q+  L K + E   + N+  ++ E +   ++    E+ N    ++ S  + ++ +     
Sbjct: 3711 QLTSLIKNINEVNEEQNKTISSFEQKHKSLIAERFELQNTIQELKDSLQQKEEQIQLFEK 3770

Query: 1564 TKQGRDEQLDNTMNKE 1579
                   +  +T+ ++
Sbjct: 3771 KNDEMQAETQDTLKQQ 3786



 Score =  192 bits (469), Expect = 5e-47
 Identities = 323/1532 (21%), Positives = 644/1532 (42%), Gaps = 147/1532 (9%)

Query: 90   ISESLANTLKQKEILMEKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSN 149
            I +S  N +K+ E    +I + KE  +   + +                 Q      L N
Sbjct: 1759 IQQSYENKIKELEQNCLQIFEQKEELQIRISQLDEEIADLKSVEKKSFEEQTESTKSLEN 1818

Query: 150  TIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXX 209
            TIKE +N ++ L  + K     ++   + I ++D+ I  + +  T               
Sbjct: 1819 TIKELENQINQLNEQNKKQNEQLVQQNQIIAQQDEQINEQTEQITQLNLQNNQQNEQIIE 1878

Query: 210  XXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISL 269
              +    Q  K+ +          +E   L + I+ K+ +I+ L+E  K LE    +++ 
Sbjct: 1879 QNQQIISQNDKIDQQ--------NEEINELNEQIKLKNEQINKLDEQIKQLEEVLNQLNS 1930

Query: 270  EHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIE 329
            +  +   +LE                 K  +  +   K + EE+G L   +  +L     
Sbjct: 1931 QIKQKDLDLEY----------------KNQLFDNL--KLQYEEQGQLLHNHQEKLKSNTI 1972

Query: 330  LLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQL 389
             L+  N  I + N++L ++L T   E+              S K   ++ ++ ++  +QL
Sbjct: 1973 KLDEQNSMIEE-NQQLISQLRTQ-LEN--------------SLKENSHSLNEQENSINQL 2016

Query: 390  SSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXG-KDTL 448
            + E L    DK+  +  I +L+    +LN+DL  K  +ISE               K  L
Sbjct: 2017 NCELLQMGQDKQQLQGLIHQLKEENSNLNEDLKQKLNIISESQQLIKEKSDIAEELKQNL 2076

Query: 449  IAQLQLEHQ-----QHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIE 503
              QLQ + +     Q ++         N + +N+I +++EQL+Q  N E  D N+++ I+
Sbjct: 2077 TNQLQKQQEYIQSIQQLQEELKESQELNEKHINKIKQLEEQLQQ--NTEKID-NLEENIQ 2133

Query: 504  KLKSAEEQITQLNDEI-DAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTE 562
            KL S +EQ    N ++ D  N+    ++S      +Q QK +D+ SK+     +   L E
Sbjct: 2134 KLISDKEQFEINNKQLQDQINQQDQLIESFE----EQFQKQLDSESKL---KLQATNLEE 2186

Query: 563  ELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQ 622
             L    QK   LE+   NL   L   +S   I+S V K     E +         + ES 
Sbjct: 2187 SLKEAQQKEILLEQ---NLTQQLESKNS--EIDSLVQKIKQNEEEIVVLNNNLEQIKESH 2241

Query: 623  KFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLE--EQIDALSASKKELAL 680
              ++ Q+L   +Q   + E  L + SQ   +Q+   ++ ++ E    I       K+L  
Sbjct: 2242 N-EITQKLENTEQLLKQSEQDL-NSSQKLVEQLEQNLEKINSENTHAIQEYEEKIKQLNS 2299

Query: 681  VIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKIN 740
             +E+L  +K+ L     D +   +DI  KLQ+ +Q  ++   + EK  A  I E    I+
Sbjct: 2300 QVESLNNEKDSLASQFMDSDAQNQDIQLKLQS-LQTELESKIEKEKQQAALIKEKQNLID 2358

Query: 741  HEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKAD 800
             +EQ+        + + ++     + ++ +L   + R+    E + +  ++   L+ K +
Sbjct: 2359 EKEQAIQLLSTEYEQREEQSQQVNKQLQHKLEALEERLTSKIEELKIQNEQNQELQNKLE 2418

Query: 801  QLGSYLQEK-QKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKE--------L 851
             L    Q+K +K   ++ +   E  N    L+      +  LL  +   K+        +
Sbjct: 2419 DLIQETQQKIEKINDQHQLGLQEKDNYYQELLKQKEQEQMNLLNDQLSEKQKQEEFMKCM 2478

Query: 852  QKKNQILLEENQNLQISLSDMQQ----HYNALVEKANRTDLAESESTKYQTQLR-DLESN 906
            Q++ Q   E+ Q  Q +  D+ Q    HY  ++   +   +   +    + +++  LE  
Sbjct: 2479 QQQEQRFQEQLQITQQNAQDLVQQKEIHYKEIISMKDEDLMKRKQEIHEKEEIKQQLEEK 2538

Query: 907  LKRITHEHQTL---IVQKKKEI---EDLEIEFNTQIESAIRDKKVLNEKYEK-------- 952
            +  + +E Q L   I+QK  +I   ED++I  N QI+   ++ +   +K E+        
Sbjct: 2539 IFNLQNELQNLKEEILQKNNDIHRQEDIQISLNKQIDELKKNLQESLQKQEESALILLER 2598

Query: 953  --NIEYVTQLEAQLQEYKNNIEN-LNMNVEELNKMNLELIDK-HVQKQQTQSPDYTEQYI 1008
              NI+   Q +    +  + ++N L  N ++ N+M L L DK HV K+Q +         
Sbjct: 2599 ENNIKQQEQAQVSQNKEIDQLKNKLQENEQKQNEMALILQDKEHVMKEQEEK---LISLN 2655

Query: 1009 NEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVS 1068
            NEIN LN  LK+  +++   +  +   +      +S+ + ++ Q   K+ + E ++ ++ 
Sbjct: 2656 NEINNLNNTLKENLQKVSERDLVLLEKEKD----ISELQEQIVQLQDKISSSELQITQLQ 2711

Query: 1069 KQLLDSKQH-NEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANN 1127
               ++ ++  N +L     +  +Q+K +++ K   +  + K+   +    I  + D  NN
Sbjct: 2712 SNSINKEEELNSKLAQQASDNQNQLKLIEDLKNQIQ-ELEKSIDSLEQLKINELQDQKNN 2770

Query: 1128 VDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNT--EL 1185
             +            +K Q+ E  IQE S + E+   LN +++  + + ++L+ +    +L
Sbjct: 2771 YELSIKNFEEEIKKIK-QDYETKIQENSQIIEE---LNVQIKS-FEQQLELQKIQNKQQL 2825

Query: 1186 TGH-DVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLA 1244
            + H + V Q Q      KLE          ++ +E+    +  +++   E  E  K    
Sbjct: 2826 SDHEEYVKQLQEEFNNKKLELQKEYETKAGASFSEIEQLHNQKINKMQEEFEEKHKNMKD 2885

Query: 1245 QREADFQKTEHELRVQLSAFESKYEQL--LDSVQSSTQEETNKI-----VTMEQVTSLQN 1297
              +++ +K + +L  Q+   +    Q+  LDS   + +E+  KI      T+++   L +
Sbjct: 2886 SLQSEIKKLQEDLEAQIQENKKLNLQIQELDSELLNAKEQKQKISQEVDETLQKNVELND 2945

Query: 1298 KLQDKEEHLRNL----QEKYADVINQIEILRSEIEDE-KVAFXXXXXXXXXXXXXXXXDL 1352
            K+Q + E + NL     E+     ++I +L+ + E + +                     
Sbjct: 2946 KIQQQIEQINNLLSKQNEERQSHQDEINLLQEKFEKQLEEVQKQNQVKLEQSHSEVEQSH 3005

Query: 1353 RTENQSYKQMQEQSILNI-NEENAQLKKSSXXXXXXXXXXXXRVNDAEA---KVLELTHQ 1408
            ++E Q   Q Q+++IL + NE   QL K              + ++ E    K+ +   Q
Sbjct: 3006 QSEIQQLLQNQQEAILKLKNELTEQLSKVQQENDLLEKQLRAKESEEEQLNDKLSQQYDQ 3065

Query: 1409 LELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHE 1468
            ++ K+S++     E    L Q+   FE ++ +LVE   +++    E E+  A +      
Sbjct: 3066 IQEKESDLVSLKEENN-KLIQKVQNFEKIKNELVEENNQLKQNIVELENSSAEI------ 3118

Query: 1469 NANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELN-KALEEEVAKTNEMQTALE 1527
            +AN  + +Q+  + E  + I + N  + +  S   Q+ ELN K L+ E     ++Q   +
Sbjct: 3119 SANLEKLIQENQDKE--QQIYDFNDNLQQKES---QIQELNSKILQIEEKYQTQIQELEK 3173

Query: 1528 NQEIEIVTLNDEITNLQNMVRASSSKIQKHVS 1559
            N +++I  L D+ T  ++ +     + Q+ +S
Sbjct: 3174 NHQVKIKDLADKFTVCEDTLVLQEKQFQEKLS 3205



 Score =  189 bits (460), Expect = 6e-46
 Identities = 279/1369 (20%), Positives = 596/1369 (43%), Gaps = 129/1369 (9%)

Query: 235  EKQRLLKDIESKDVR--ISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXX 292
            +KQ  L + ++++V+  I +LE+  K L      +  E   +++ L+Q            
Sbjct: 1121 KKQNQLLETQNQNVQKNIQTLEQTIKTLNEQNKSLQKEKESISKNLQQKTQNLAKSEDQV 1180

Query: 293  XXLAKQS---------IEPSCEEKTEIEEKGSLEIA------------------NMTELT 325
                 ++         +E   +E  E ++K S   A                   + +  
Sbjct: 1181 AQFKNENKLYQEKCGILEKRIKELEETKKKSSTPSAGTSPNSKGKNQNTQQQQQQLQQYI 1240

Query: 326  KKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSP 385
            K  E L+ L  +  Q   E E   + +  E + + S  ++   +I ++   N   K  + 
Sbjct: 1241 KDCEQLKQLLIEYEQKFLEKEEDKSKLLAEIEDLKSKLEEAVTIIKQQEEENGKIKQNNQ 1300

Query: 386  WS-QLSSETLNQDTDKKINK-NEIAKLEMVIQSLNKDLVD-KEYVISEKDTXXXXXXXXX 442
             S     E L ++ ++ + +  ++ K +  I +  +D ++  +  +SEK           
Sbjct: 1301 NSTSFLKEKLKEEIEQNLKRVKDLEKEKEDIANEQQDKIELYQNSLSEKQQEIDELISKN 1360

Query: 443  XGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQL--KQELNDEIKDVNVKD 500
               + LI Q Q E ++  E    I       ++++   +Q+QL  K +L + +K+ ++ D
Sbjct: 1361 NNLNELIDQYQREIKKCKEKMEEIKKMQEKVNLDQQKNMQDQLAQKNKLIEMMKNDSLDD 1420

Query: 501  LIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSK-VSDSNKEIVR 559
              E+++  +++I +L  ++ A     +   S  + + K+ Q+  + F K +   N++I +
Sbjct: 1421 K-EEIELLKQEIEELKQQLQATQSKPLS-SSRQESQYKEFQQKEEEFKKLIKQQNEKIAK 1478

Query: 560  LTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIE-MENLAETRLKAISL 618
            + ++     QK+ E EEE   LQ  L    S     +D  KK  + ++ +     + I  
Sbjct: 1479 MEQD---CLQKM-EFEEEIARLQQEL---QSALDSHNDSGKKQNQSIDQIIND--QDIDG 1529

Query: 619  LESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVC--SEIKSV--HLEEQIDALSAS 674
            L++++ +       LQ++  E+E++  D+ ++Q+++ C   +I+ +    +E+ D L ++
Sbjct: 1530 LQNKR-NQQNSFEDLQERVKELEEENNDLREIQNERDCLQQQIQEIIDKNKEETDQLQST 1588

Query: 675  KKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLE----KMSAE 730
             + L   I+  ++D E++   +++        + + +  IQ+     D+ E    ++  E
Sbjct: 1589 VRLLTQQIQKNQIDSEKIIQNLQNEIGSMTQFIKQQEQLIQQQNAEHDQKEIEFRQIIKE 1648

Query: 731  K----------ISELLAKINHEEQSKIQTQFGIDAKIQ--ERDLYIENIESELSKYKSRI 778
            K          I ++  +I  +    IQ Q  I+   Q  E+ L I N +   S    +I
Sbjct: 1649 KDNYIFTQRDQIEQITDQIKEKNNQLIQMQENIEELKQNYEQQLQINNDQISNSNQNFQI 1708

Query: 779  CRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVE 838
             ++E    + E+           L + +QE  +A S+   +  E+  + +V+        
Sbjct: 1709 -QIENLQKLREEEEKYQNSNLSDLNNQIQELNQALSQKEEELQEINMKQSVIQQ------ 1761

Query: 839  KQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTK-YQ 897
                  E++ KEL++    + E+ + LQI +S + +    L     ++   ++ESTK  +
Sbjct: 1762 ----SYENKIKELEQNCLQIFEQKEELQIRISQLDEEIADLKSVEKKSFEEQTESTKSLE 1817

Query: 898  TQLRDLESNLKRITHEHQ---TLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNI 954
              +++LE+ + ++  +++     +VQ+ + I   + + N Q E   +     N++ E+ I
Sbjct: 1818 NTIKELENQINQLNEQNKKQNEQLVQQNQIIAQQDEQINEQTEQITQLNLQNNQQNEQII 1877

Query: 955  EYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKL 1014
            E   Q+ +Q     + I+  N  + ELN+  ++L ++ + K   Q     +Q    +N+L
Sbjct: 1878 EQNQQIISQ----NDKIDQQNEEINELNE-QIKLKNEQINKLDEQ----IKQLEEVLNQL 1928

Query: 1015 NALLKQKDEEIIALNQKINNAQVSYM---SMVSDYESKLAQFTTKLE---NMEEEMQRVS 1068
            N+ +KQKD ++   NQ  +N ++ Y     ++ +++ KL   T KL+   +M EE Q++ 
Sbjct: 1929 NSQIKQKDLDLEYKNQLFDNLKLQYEEQGQLLHNHQEKLKSNTIKLDEQNSMIEENQQLI 1988

Query: 1069 KQLLDSKQHN-EELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANN 1127
             QL    +++ +E    + EQ++ I +L    L    +  + +G+     I  + ++ +N
Sbjct: 1989 SQLRTQLENSLKENSHSLNEQENSINQLNCELLQMGQDKQQLQGL-----IHQLKEENSN 2043

Query: 1128 VDXXXXXXXXXXXXLKVQEEEEFIQERS-VLQEQSAKLNTELQECYTKIIQLETLNTELT 1186
            ++              + E ++ I+E+S + +E    L  +LQ+    I  ++ L  EL 
Sbjct: 2044 LNEDLKQKLNI-----ISESQQLIKEKSDIAEELKQNLTNQLQKQQEYIQSIQQLQEELK 2098

Query: 1187 GHDVVNQEQINQLKSKLEQL--NTEN-DNLLSTVAELRSSISSAVDQRGFEIAELWKQ-H 1242
                +N++ IN++K   EQL  NTE  DNL   + +L S      D+  FEI     Q  
Sbjct: 2099 ESQELNEKHINKIKQLEEQLQQNTEKIDNLEENIQKLIS------DKEQFEINNKQLQDQ 2152

Query: 1243 LAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDK 1302
            + Q++   +  E + + QL + ESK +    +++ S +E   K + +EQ  +L  +L+ K
Sbjct: 2153 INQQDQLIESFEEQFQKQLDS-ESKLKLQATNLEESLKEAQQKEILLEQ--NLTQQLESK 2209

Query: 1303 EEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQM 1362
               + +L +K      +I +L + +E  K +                   +  N S K +
Sbjct: 2210 NSEIDSLVQKIKQNEEEIVVLNNNLEQIKESHNEITQKLENTEQLLKQSEQDLNSSQKLV 2269

Query: 1363 Q--EQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKT 1420
            +  EQ++  IN EN    +               +N+ +  +       + ++ +I  K 
Sbjct: 2270 EQLEQNLEKINSENTHAIQEYEEKIKQLNSQVESLNNEKDSLASQFMDSDAQNQDIQLKL 2329

Query: 1421 HEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKES 1480
                   T+   + E  +QQ    +++ ++L  EKE  + +L  +  +     + + K+ 
Sbjct: 2330 QSLQ---TELESKIEKEKQQAALIKEK-QNLIDEKEQAIQLLSTEYEQREEQSQQVNKQL 2385

Query: 1481 EIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQ 1529
            + +   L E L  KI E    N+Q  EL   LE+ + +T +    + +Q
Sbjct: 2386 QHKLEALEERLTSKIEELKIQNEQNQELQNKLEDLIQETQQKIEKINDQ 2434



 Score =  187 bits (456), Expect = 2e-45
 Identities = 310/1476 (21%), Positives = 623/1476 (42%), Gaps = 159/1476 (10%)

Query: 212  EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271
            E    Q+ +     I M+   ++ KQ   + ++  + +IS+  +         F+I +E+
Sbjct: 1661 EQITDQIKEKNNQLIQMQENIEELKQNYEQQLQINNDQISNSNQ--------NFQIQIEN 1712

Query: 272  -SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIEL 330
              KL +E E+                 Q++    EE  EI  K S+ I    E   KI+ 
Sbjct: 1713 LQKLREEEEKYQNSNLSDLNNQIQELNQALSQKEEELQEINMKQSV-IQQSYE--NKIKE 1769

Query: 331  LEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKG--SPLISRKSGRNTASKMKSPWSQ 388
            LE    QI +  +EL+ +++ +  E   + S  KK       S KS  NT  ++++  +Q
Sbjct: 1770 LEQNCLQIFEQKEELQIRISQLDEEIADLKSVEKKSFEEQTESTKSLENTIKELENQINQ 1829

Query: 389  LSSETLNQDTDKKINKNEI-AKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDT 447
            L+ +   Q+ ++ + +N+I A+ +  I    + +       ++++            ++ 
Sbjct: 1830 LNEQNKKQN-EQLVQQNQIIAQQDEQINEQTEQITQLNLQNNQQNEQIIEQNQQIISQND 1888

Query: 448  LIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKS 507
             I Q   E  +  E      +    E +N++ +  +QL++ LN     +  KDL  + K+
Sbjct: 1889 KIDQQNEEINELNE-----QIKLKNEQINKLDEQIKQLEEVLNQLNSQIKQKDLDLEYKN 1943

Query: 508  AEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIV-----RLTE 562
                  QL D +    +   ++  NH+ KLK     +D  + + + N++++     +L  
Sbjct: 1944 ------QLFDNLKLQYEEQGQLLHNHQEKLKSNTIKLDEQNSMIEENQQLISQLRTQLEN 1997

Query: 563  ELHHLSQKVAELEEEKGNLQLHLVDYDSGRM-IESDVYKKMIEMENLAETRLKAISLL-E 620
             L   S  + E E     L   L+     +  ++  +++   E  NL E   + ++++ E
Sbjct: 1998 SLKENSHSLNEQENSINQLNCELLQMGQDKQQLQGLIHQLKEENSNLNEDLKQKLNIISE 2057

Query: 621  SQ-----KFDLVQEL-HILQQKYDEVEDKLADISQLQSD-QVCSEIKSVH------LEEQ 667
            SQ     K D+ +EL   L  +  + ++ +  I QLQ + +   E+   H      LEEQ
Sbjct: 2058 SQQLIKEKSDIAEELKQNLTNQLQKQQEYIQSIQQLQEELKESQELNEKHINKIKQLEEQ 2117

Query: 668  IDALSASKKELALVIENLKLDKEQLYGTIKDLE---NDKEDIMNKLQNYIQENMDLTDKL 724
            +   +     L   I+ L  DKEQ     K L+   N ++ ++   +   Q+ +D   KL
Sbjct: 2118 LQQNTEKIDNLEENIQKLISDKEQFEINNKQLQDQINQQDQLIESFEEQFQKQLDSESKL 2177

Query: 725  EKMSAEKISELLAKINHEE---QSKIQTQFG-----IDAKIQ-----ERDLYI-----EN 766
             K+ A  + E L +   +E   +  +  Q       ID+ +Q     E ++ +     E 
Sbjct: 2178 -KLQATNLEESLKEAQQKEILLEQNLTQQLESKNSEIDSLVQKIKQNEEEIVVLNNNLEQ 2236

Query: 767  IESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQ----EKQKAYSEYTIQEDE 822
            I+   ++   ++   E+ +   E    S ++  +QL   L+    E   A  EY  +  +
Sbjct: 2237 IKESHNEITQKLENTEQLLKQSEQDLNSSQKLVEQLEQNLEKINSENTHAIQEYEEKIKQ 2296

Query: 823  LVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEK 882
            L +++  L +    +  Q ++ + +N+++Q K Q L  E   L+  +   +Q    + EK
Sbjct: 2297 LNSQVESLNNEKDSLASQFMDSDAQNQDIQLKLQSLQTE---LESKIEKEKQQAALIKEK 2353

Query: 883  ANRTDLAESE----STKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEI--EFNTQI 936
             N  D  E      ST+Y+ +    +   K++ H+ + L  +   +IE+L+I  E N ++
Sbjct: 2354 QNLIDEKEQAIQLLSTEYEQREEQSQQVNKQLQHKLEALEERLTSKIEELKIQNEQNQEL 2413

Query: 937  ESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENL--NMNVEELNKMNLELIDKHVQ 994
            ++ + D  ++ E  +K  +   Q +  LQE  N  + L      E++N +N +L +K  Q
Sbjct: 2414 QNKLED--LIQETQQKIEKINDQHQLGLQEKDNYYQELLKQKEQEQMNLLNDQLSEKQKQ 2471

Query: 995  KQQTQSPDYTEQYINE---INKLNA--LLKQKDEEIIALNQKINNAQVSYMSMVSDYESK 1049
            ++  +     EQ   E   I + NA  L++QK+     +    +   +     + + E  
Sbjct: 2472 EEFMKCMQQQEQRFQEQLQITQQNAQDLVQQKEIHYKEIISMKDEDLMKRKQEIHEKEEI 2531

Query: 1050 LAQFTTKLENMEEEMQRVSKQLLDSKQ---HNEELQILVREQDDQIKE-LKETK------ 1099
              Q   K+ N++ E+Q + +++L         E++QI + +Q D++K+ L+E+       
Sbjct: 2532 KQQLEEKIFNLQNELQNLKEEILQKNNDIHRQEDIQISLNKQIDELKKNLQESLQKQEES 2591

Query: 1100 ----LTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERS 1155
                L  E NI + E   +S   E +    N +             L+ +E     QE  
Sbjct: 2592 ALILLERENNIKQQEQAQVSQNKE-IDQLKNKLQENEQKQNEMALILQDKEHVMKEQEEK 2650

Query: 1156 V--LQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLE----QLNTE 1209
            +  L  +   LN  L+E   K+ + + +  E        QEQI QL+ K+     Q+   
Sbjct: 2651 LISLNNEINNLNNTLKENLQKVSERDLVLLEKEKDISELQEQIVQLQDKISSSELQITQL 2710

Query: 1210 NDNLLSTVAELRSSISSAV--DQRGFEIAELWKQHLAQREADFQKTE----HELRVQLSA 1263
              N ++   EL S ++     +Q   ++ E  K  + + E      E    +EL+ Q + 
Sbjct: 2711 QSNSINKEEELNSKLAQQASDNQNQLKLIEDLKNQIQELEKSIDSLEQLKINELQDQKNN 2770

Query: 1264 FESKYEQLLDSVQSSTQEETNKIVTMEQVT---SLQNKLQDKEEHLRNLQEKY--ADVIN 1318
            +E   +   + ++   Q+   KI    Q+    ++Q K  +++  L+ +Q K   +D   
Sbjct: 2771 YELSIKNFEEEIKKIKQDYETKIQENSQIIEELNVQIKSFEQQLELQKIQNKQQLSDHEE 2830

Query: 1319 QIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLK 1378
             ++ L+ E  ++K+                   L   NQ   +MQE+      E++  +K
Sbjct: 2831 YVKQLQEEFNNKKLELQKEYETKAGASFSEIEQLH--NQKINKMQEE----FEEKHKNMK 2884

Query: 1379 KSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVR 1438
             S                  ++++ +L   LE +     Q+  +  + + + + E  N +
Sbjct: 2885 DS-----------------LQSEIKKLQEDLEAQ----IQENKKLNLQIQELDSELLNAK 2923

Query: 1439 QQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKE---SEIERVKLIEELNVKI 1495
            +Q  +  + +++ T +K  EL     +  E  N+  + Q E   S  + + L++E   K 
Sbjct: 2924 EQKQKISQEVDE-TLQKNVELNDKIQQQIEQINNLLSKQNEERQSHQDEINLLQEKFEKQ 2982

Query: 1496 TESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQ 1555
             E V    QV       E E +  +E+Q  L+NQ+  I+ L +E+T   + V+  +  ++
Sbjct: 2983 LEEVQKQNQVKLEQSHSEVEQSHQSEIQQLLQNQQEAILKLKNELTEQLSKVQQENDLLE 3042

Query: 1556 KHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDL 1591
            K +      K+  +EQL++ ++++  D +   E DL
Sbjct: 3043 KQLR----AKESEEEQLNDKLSQQ-YDQIQEKESDL 3073



 Score =  173 bits (421), Expect = 3e-41
 Identities = 265/1337 (19%), Positives = 589/1337 (44%), Gaps = 110/1337 (8%)

Query: 317  EIANMTELTKKIEL-LEHLNCQI--RQTNK--ELENKLATMGTESKAVSSPSKKGSPLIS 371
            E+ N+ +  ++I++ L+H   ++   Q NK  ELE KL     E+  + S  K+   L+ 
Sbjct: 987  ELDNIDDGFERIQIKLQHARQELDQEQANKIIELEKKLLIKQDETGRLESQIKELQQLVK 1046

Query: 372  RKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDL--VDKEYVIS 429
            +++ +N++ K+++      + T++   + + ++  I  L+  IQ L +++   + ++ I 
Sbjct: 1047 KQNKQNSSPKIQNQQQDSRNYTVSAAVETEEDQKLINSLQNQIQKLKQEIQKANTDFNII 1106

Query: 430  EKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQEL 489
            + D            K   + + Q ++ Q         + T  E    + K +E + + L
Sbjct: 1107 KDDNKSFVSQIEILKKQNQLLETQNQNVQKNIQTLEQTIKTLNEQNKSLQKEKESISKNL 1166

Query: 490  NDEIKDV-NVKDLIEKLKSA-----------EEQITQLNDEIDAANKNMIKVKSNHKLKL 537
              + +++   +D + + K+            E++I +L +    ++        N K K 
Sbjct: 1167 QQKTQNLAKSEDQVAQFKNENKLYQEKCGILEKRIKELEETKKKSSTPSAGTSPNSKGK- 1225

Query: 538  KQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESD 597
               Q T     ++    K+  +L + L    QK  E EE+K  L   + D  S ++ E+ 
Sbjct: 1226 --NQNTQQQQQQLQQYIKDCEQLKQLLIEYEQKFLEKEEDKSKLLAEIEDLKS-KLEEAV 1282

Query: 598  VYKKMIEMEN--LAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQV 655
               K  E EN  + +    + S L+ +   L +E+    ++  ++E +  DI+  Q D++
Sbjct: 1283 TIIKQQEEENGKIKQNNQNSTSFLKEK---LKEEIEQNLKRVKDLEKEKEDIANEQQDKI 1339

Query: 656  CSEIKSVHLEEQ-IDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYI 714
                 S+  ++Q ID L +    L  +I+  + + ++    +++++  +E +    Q  +
Sbjct: 1340 ELYQNSLSEKQQEIDELISKNNNLNELIDQYQREIKKCKEKMEEIKKMQEKVNLDQQKNM 1399

Query: 715  QENMDLTDKL-EKMSAEKIS-----ELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIE 768
            Q+ +   +KL E M  + +      ELL +   E + ++Q           ++   +  +
Sbjct: 1400 QDQLAQKNKLIEMMKNDSLDDKEEIELLKQEIEELKQQLQATQSKPLSSSRQESQYKEFQ 1459

Query: 769  SELSKYKSRICRLEESIAVMED---RRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVN 825
             +  ++K  I +  E IA ME    ++   E +  +L   LQ    ++++   ++++ ++
Sbjct: 1460 QKEEEFKKLIKQQNEKIAKMEQDCLQKMEFEEEIARLQQELQSALDSHNDSGKKQNQSID 1519

Query: 826  RLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSD---MQQHYNALVEK 882
            ++    D D +  K+  +   E  +LQ++ + L EEN +L+   ++   +QQ    +++K
Sbjct: 1520 QIINDQDIDGLQNKRNQQNSFE--DLQERVKELEEENNDLREIQNERDCLQQQIQEIIDK 1577

Query: 883  ANRTDLAESEST-KYQTQ------------LRDLESNLKRITH---EHQTLIVQKKKEIE 926
             N+ +  + +ST +  TQ            +++L++ +  +T    + + LI Q+  E +
Sbjct: 1578 -NKEETDQLQSTVRLLTQQIQKNQIDSEKIIQNLQNEIGSMTQFIKQQEQLIQQQNAEHD 1636

Query: 927  DLEIEFNTQIES------AIRDK--KVLNEKYEKNIEYVTQLEAQLQEYKNNIEN-LNMN 977
              EIEF   I+         RD+  ++ ++  EKN + + Q++  ++E K N E  L +N
Sbjct: 1637 QKEIEFRQIIKEKDNYIFTQRDQIEQITDQIKEKNNQLI-QMQENIEELKQNYEQQLQIN 1695

Query: 978  VEELNK--MNLELIDKHVQKQQTQSPDYTEQYI----NEINKLNALLKQKDEEIIALNQK 1031
             ++++    N ++  +++QK + +   Y    +    N+I +LN  L QK+EE+  +N K
Sbjct: 1696 NDQISNSNQNFQIQIENLQKLREEEEKYQNSNLSDLNNQIQELNQALSQKEEELQEINMK 1755

Query: 1032 INNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLD----SKQHNEELQILVRE 1087
             +  Q SY + + + E    Q   + E ++  + ++ +++ D     K+  EE     + 
Sbjct: 1756 QSVIQQSYENKIKELEQNCLQIFEQKEELQIRISQLDEEIADLKSVEKKSFEEQTESTKS 1815

Query: 1088 QDDQIKELK-ETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQE 1146
             ++ IKEL+ +     E N  + E ++  + I    D+  N                 Q+
Sbjct: 1816 LENTIKELENQINQLNEQNKKQNEQLVQQNQIIAQQDEQINEQTEQITQLNLQNN---QQ 1872

Query: 1147 EEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQL 1206
             E+ I++   +  Q+ K++ + +E      Q++  N ++   D    EQI QL+  L QL
Sbjct: 1873 NEQIIEQNQQIISQNDKIDQQNEEINELNEQIKLKNEQINKLD----EQIKQLEEVLNQL 1928

Query: 1207 NTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFES 1266
            N++         E ++ +   +  +  E  +L   H  + +++  K + E    +   + 
Sbjct: 1929 NSQIKQ-KDLDLEYKNQLFDNLKLQYEEQGQLLHNHQEKLKSNTIKLD-EQNSMIEENQQ 1986

Query: 1267 KYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSE 1326
               QL   +++S +E ++ +   EQ  S+ N+L  +   +   +++   +I+Q++   S 
Sbjct: 1987 LISQLRTQLENSLKENSHSL--NEQENSI-NQLNCELLQMGQDKQQLQGLIHQLKEENSN 2043

Query: 1327 IED---EKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXX 1383
            + +   +K+                  +L+    +  Q Q++ I +I +   +LK+S   
Sbjct: 2044 LNEDLKQKLNIISESQQLIKEKSDIAEELKQNLTNQLQKQQEYIQSIQQLQEELKESQ-E 2102

Query: 1384 XXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVE 1443
                      ++ +   +  E    LE    ++     ++ I   Q  D+  N + QL+E
Sbjct: 2103 LNEKHINKIKQLEEQLQQNTEKIDNLEENIQKLISDKEQFEINNKQLQDQI-NQQDQLIE 2161

Query: 1444 -YEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSL- 1501
             +E++ +    + ES+L +    + E+    E  QKE  +E+  L ++L  K +E  SL 
Sbjct: 2162 SFEEQFQK-QLDSESKLKLQATNLEESLK--EAQQKEILLEQ-NLTQQLESKNSEIDSLV 2217

Query: 1502 ------NKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQ 1555
                   +++  LN  LE+     NE+   LEN E  +     ++ + Q +V      ++
Sbjct: 2218 QKIKQNEEEIVVLNNNLEQIKESHNEITQKLENTEQLLKQSEQDLNSSQKLVEQLEQNLE 2277

Query: 1556 KHVSFASDTKQGRDEQL 1572
            K  S  +   Q  +E++
Sbjct: 2278 KINSENTHAIQEYEEKI 2294



 Score =  167 bits (407), Expect = 2e-39
 Identities = 302/1452 (20%), Positives = 637/1452 (43%), Gaps = 162/1452 (11%)

Query: 149  NTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXX 208
            + +KE++  L  L  ++  +  T+ +  +K++E+D ++  K K  +              
Sbjct: 2642 HVMKEQEEKLISLNNEINNLNNTLKENLQKVSERDLVLLEKEKDISELQEQIVQLQDKIS 2701

Query: 209  XXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEIS 268
                 ++ Q+T++Q N I  E E   +  +   D +++   I  L+  N++ E  +   S
Sbjct: 2702 S----SELQITQLQSNSINKEEELNSKLAQQASDNQNQLKLIEDLK--NQIQELEKSIDS 2755

Query: 269  LEHSKLAQELEQXXXXXXXXXXXXXXLAK--QSIEPSCEEKTEIEEKGSLEIANMT---E 323
            LE  K+ +  +Q              + K  Q  E   +E ++I E+ +++I +     E
Sbjct: 2756 LEQLKINELQDQKNNYELSIKNFEEEIKKIKQDYETKIQENSQIIEELNVQIKSFEQQLE 2815

Query: 324  LTK---KIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPS-KKGSPLISRKSGR--- 376
            L K   K +L +H    ++Q  +E  NK   +  E +  +  S  +   L ++K  +   
Sbjct: 2816 LQKIQNKQQLSDHEE-YVKQLQEEFNNKKLELQKEYETKAGASFSEIEQLHNQKINKMQE 2874

Query: 377  NTASKMKSPWSQLSSET--LNQDTDKKINKNEIAKLEMVIQSLNKDLV---DKEYVISEK 431
                K K+    L SE   L +D + +I +N+  KL + IQ L+ +L+   +++  IS++
Sbjct: 2875 EFEEKHKNMKDSLQSEIKKLQEDLEAQIQENK--KLNLQIQELDSELLNAKEQKQKISQE 2932

Query: 432  DTXXXXXXXXXXGK--------DTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQE 483
                         K        + L+++   E Q H +  +L+      + + E+ K  +
Sbjct: 2933 VDETLQKNVELNDKIQQQIEQINNLLSKQNEERQSHQDEINLLQEKFEKQ-LEEVQKQNQ 2991

Query: 484  QLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQ-- 541
               ++ + E++  +  ++ + L++ +E I +L +E+    + + KV+  + L  KQ++  
Sbjct: 2992 VKLEQSHSEVEQSHQSEIQQLLQNQQEAILKLKNEL---TEQLSKVQQENDLLEKQLRAK 3048

Query: 542  ---------KTIDNFSKVSDSNKEIVRLTEELHHLSQKVA-------ELEEEKGNLQLHL 585
                     K    + ++ +   ++V L EE + L QKV        EL EE   L+ ++
Sbjct: 3049 ESEEEQLNDKLSQQYDQIQEKESDLVSLKEENNKLIQKVQNFEKIKNELVEENNQLKQNI 3108

Query: 586  VDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLA 645
            V+ ++     S   +K+I+     E ++   +    QK   +QEL+    K  ++E+K  
Sbjct: 3109 VELENSSAEISANLEKLIQENQDKEQQIYDFNDNLQQKESQIQELN---SKILQIEEKYQ 3165

Query: 646  DISQLQSDQVCSEIKSVHLEEQI----DALSASKKELALVIENLKLDKEQLYGT-IKDLE 700
              +Q+Q  +   ++K   L ++     D L   +K+    + NL+ +K  L  T  + L+
Sbjct: 3166 --TQIQELEKNHQVKIKDLADKFTVCEDTLVLQEKQFQEKLSNLQ-EKYNLEQTNYESLQ 3222

Query: 701  NDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQER 760
             D ++I ++L N +QE  +L  ++E       + +L++   EE+  + ++   + + Q  
Sbjct: 3223 IDHQNIQSQL-NLLQE--ELQKQIEG------NHILSQKQQEEKDLV-SENSQNLQQQNL 3272

Query: 761  DLYIENIESE--LSKYKSRICRLEESIAVMEDRRYSLERKADQLG----SYLQEKQKAYS 814
            DL+ EN ES+  + + K ++ +LEE I  + D +   + + +++     + ++EK+K   
Sbjct: 3273 DLHKENEESKAKIQQMKEKLSQLEEQIEKVNDDKQKSQEENEKMRIEKETEIEEKEKEIQ 3332

Query: 815  EYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKK-NQI---------LLEENQN 864
            +  +Q  +L     V+ +  + ++   +E+E   K+L ++ NQI         L EE  N
Sbjct: 3333 KLKVQIQDLEG---VMEEQTQQIQTANVEVEKFKKDLDERYNQIAFLEDILKQLEEEKNN 3389

Query: 865  LQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDL----ESNLKRITHEHQTLIVQ 920
            LQ +L++     NAL+++ N     E        ++ +L    E NL+ I      L+  
Sbjct: 3390 LQNTLNECD---NALIQERNERATVEETINLLNDKITNLQIEREDNLEIIEKLKADLLQS 3446

Query: 921  KKKEIEDLEIEFN-----TQIESAIRDKKVLNEKYEKNIEYVTQ---LEAQLQEYKNNIE 972
            + ++     I+ +     +Q  S+   K+ +++    N E + Q   LE +++EY+   E
Sbjct: 3447 QPQKQNSSPIKLSLPQTSSQAGSSSAQKQQIDQLTFANAELLDQINELELEIKEYQREKE 3506

Query: 973  NLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKI 1032
             +    ++L K  +EL+ K +Q +Q  +     + I +   +   L+Q ++E     QK 
Sbjct: 3507 EILDENDKLTK-EIELL-KGLQGEQPVNRKV--ELIEDREIMEQELQQLNQEQQVQKQK- 3561

Query: 1033 NNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQI 1092
               + S  + +SD +S L Q    ++ +EEE+    K+L + K+ + +L+ +  +Q+ + 
Sbjct: 3562 ---RASLQNEMSDLKSILEQNIVVIQTLEEEIVNYKKKLAE-KEESLQLKQVANDQNSE- 3616

Query: 1093 KELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEE---- 1148
               + +K+  E++I K E   + + I  +    +  D            L    E+    
Sbjct: 3617 ---RFSKIEEELDISKHENQNLKNQITQLEQQLSEKDYHLEQQHNSICELSAMIEKFENQ 3673

Query: 1149 ----EFIQE-RSVLQEQSAKLNTELQECY-TKIIQLETLNTELTGHDVVNQEQ---INQL 1199
                E I+  + +  ++  KL  E  E   +K  +++ L + +   + VN+EQ   I+  
Sbjct: 3674 KSDAEVIENLKQMHTDKMKKLVKEHNEALASKDKEIKQLTSLIKNINEVNEEQNKTISSF 3733

Query: 1200 KSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRV 1259
            + K + L  E   L +T+ EL+ S+    +Q   ++ E     +     D  K + EL  
Sbjct: 3734 EQKHKSLIAERFELQNTIQELKDSLQQKEEQ--IQLFEKKNDEMQAETQDTLKQQKELNQ 3791

Query: 1260 QLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQ 1319
            QL   + K    L   Q++    + K+ + E     Q+  +  E+ +R LQE+      +
Sbjct: 3792 QLETLKEK----LSHFQTNMTNPSEKLSSEEDAIGYQS-AKRYEDQIRELQEEIQKRTRE 3846

Query: 1320 IEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQE---QSILNIN---EE 1373
             E LR+E E E +                     ++ Q  + +++    +I  +N   E+
Sbjct: 3847 KEQLRTEKEIECIGLKQEMDRLQKLCDRLTEQEESQKQLKEVLEDHKNDAIQKLNKEKEK 3906

Query: 1374 NAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDE 1433
            N ++KK                ++   K  +  H      S+  ++   Y     Q+  E
Sbjct: 3907 NKEMKKYLEEAHQEIEQLRKNRHEKHEKDGDNDHHQRKLSSKEDEEDAVY-----QKYKE 3961

Query: 1434 FENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQK----ESEIE-RVKLI 1488
             E    +++  +K++ED     +SEL      +++N + YE   K    + E+E +++L 
Sbjct: 3962 LEEKLTKILTEKKQLEDQNKSLQSELQ--NKSIYDNESFYEFQNKLLKSKQELEDKIELE 4019

Query: 1489 EELNVKITESVS 1500
            ++L + +   V+
Sbjct: 4020 QQLEICLERLVN 4031



 Score =  136 bits (328), Expect = 6e-30
 Identities = 272/1438 (18%), Positives = 594/1438 (41%), Gaps = 118/1438 (8%)

Query: 212  EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271
            ED      K+ E  +      ++E ++L   I + +++    ++  + L     E   E+
Sbjct: 720  EDNDAYYKKLFEEKVEGIQVLREENKQLQLQIHNLELKSYDKKKNLQKLYRIITEKDDEN 779

Query: 272  SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTE--IEEKGSLE--IANMTELTKK 327
             KL  +L+Q               A QSIE    +K +  IE+    E  I N+      
Sbjct: 780  KKLKYQLQQKEQIDRESLNQ----AIQSIEEQLNQKMQLFIEDLAYKERIIENLQVNLFY 835

Query: 328  IELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWS 387
              ++++   +  Q N   +N+  T    S  +    +K   L+S     N   +    + 
Sbjct: 836  DNIIQNEKMRGEQINNVFQNQQETEQPISDKLIELRQKREDLLSILQNNNNYDQ----YG 891

Query: 388  QLSSETLNQDTDKKINKNEIAKLEMVIQSLNK-DLVDKEYVISEKDTXXXXXXXXXXGKD 446
              + +  N +  K++      ++E  IQ LN  +   K+ V ++ D            K+
Sbjct: 892  NENEQQQNLNDIKELLGFIDQEIENEIQFLNNINQQQKQEVDNQNDQQVFAQDIPTSLKE 951

Query: 447  TLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLK 506
                QLQ E QQ ++  S++ +    +  NE  +V +QLK  LN+E  D N+ D  E+++
Sbjct: 952  ----QLQKEIQQ-LKDQSILEL----QQYNE--EVIQQLKNILNEEELD-NIDDGFERIQ 999

Query: 507  SAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELH- 565
               +   Q   E+D    N I ++   KL +KQ     D   ++    KE+ +L ++ + 
Sbjct: 1000 IKLQHARQ---ELDQEQANKI-IELEKKLLIKQ-----DETGRLESQIKELQQLVKKQNK 1050

Query: 566  -HLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKF 624
             + S K+   +++  N       Y     +E++  +K+I        +LK      +  F
Sbjct: 1051 QNSSPKIQNQQQDSRN-------YTVSAAVETEEDQKLINSLQNQIQKLKQEIQKANTDF 1103

Query: 625  DLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIEN 684
            +++++ +       E+  K   + + Q+  V   I++  LE+ I  L+   K L    E+
Sbjct: 1104 NIIKDDNKSFVSQIEILKKQNQLLETQNQNVQKNIQT--LEQTIKTLNEQNKSLQKEKES 1161

Query: 685  LKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAE---KISELLAKINH 741
            +  + +Q    +   E+      N+ + Y QE   + +K  K   E   K S   A  + 
Sbjct: 1162 ISKNLQQKTQNLAKSEDQVAQFKNENKLY-QEKCGILEKRIKELEETKKKSSTPSAGTSP 1220

Query: 742  EEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEES----IAVMEDRRYSLER 797
              + K Q       ++Q+     E ++  L +Y+ +    EE     +A +ED +  LE 
Sbjct: 1221 NSKGKNQNTQQQQQQLQQYIKDCEQLKQLLIEYEQKFLEKEEDKSKLLAEIEDLKSKLEE 1280

Query: 798  KADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQI 857
                +    +E  K           L  +L   ++ +    K++ ++E E +++  + Q 
Sbjct: 1281 AVTIIKQQEEENGKIKQNNQNSTSFLKEKLKEEIEQNL---KRVKDLEKEKEDIANEQQD 1337

Query: 858  LLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTL 917
             +E  QN   SLS+ QQ  + L+ K N  +       +YQ +++  +  ++ I    + +
Sbjct: 1338 KIELYQN---SLSEKQQEIDELISKNNNLN---ELIDQYQREIKKCKEKMEEIKKMQEKV 1391

Query: 918  IVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQ----------EY 967
             + ++K ++D   + N  IE    D     E+ E   + + +L+ QLQ            
Sbjct: 1392 NLDQQKNMQDQLAQKNKLIEMMKNDSLDDKEEIELLKQEIEELKQQLQATQSKPLSSSRQ 1451

Query: 968  KNNIENLNMNVEELNKMNLELIDKHVQKQQ--TQSPDYTEQYINEINKLNALLKQKDE-- 1023
            ++  +      EE  K+  +  +K  + +Q   Q  ++ E+      +L + L   ++  
Sbjct: 1452 ESQYKEFQQKEEEFKKLIKQQNEKIAKMEQDCLQKMEFEEEIARLQQELQSALDSHNDSG 1511

Query: 1024 --EIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEEL 1081
              +  +++Q IN+  +  +    + ++       +++ +EEE   + +   +     +++
Sbjct: 1512 KKQNQSIDQIINDQDIDGLQNKRNQQNSFEDLQERVKELEEENNDLREIQNERDCLQQQI 1571

Query: 1082 QILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXX 1141
            Q ++ +  ++  +L+ T       I K + +     I+ + ++  ++             
Sbjct: 1572 QEIIDKNKEETDQLQSTVRLLTQQIQKNQ-IDSEKIIQNLQNEIGSMTQFIKQQEQLIQQ 1630

Query: 1142 LKVQEEEEFIQERSVLQE----------QSAKLNTELQECYTKIIQLETLNTELTGHDVV 1191
               + +++ I+ R +++E          Q  ++  +++E   ++IQ++  N E    +  
Sbjct: 1631 QNAEHDQKEIEFRQIIKEKDNYIFTQRDQIEQITDQIKEKNNQLIQMQE-NIEELKQNYE 1689

Query: 1192 NQEQIN--QLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREAD 1249
             Q QIN  Q+ +  +    + +NL     E     +S +     +I EL  Q L+Q+E +
Sbjct: 1690 QQLQINNDQISNSNQNFQIQIENLQKLREEEEKYQNSNLSDLNNQIQEL-NQALSQKEEE 1748

Query: 1250 FQKTEHELRVQLSAFESKYEQL-LDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRN 1308
             Q+   +  V   ++E+K ++L  + +Q   Q+E  +I    +++ L  ++ D +   + 
Sbjct: 1749 LQEINMKQSVIQQSYENKIKELEQNCLQIFEQKEELQI----RISQLDEEIADLKSVEKK 1804

Query: 1309 LQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSIL 1368
              E+  +    +E    E+E++                     +  +++   +  EQ I 
Sbjct: 1805 SFEEQTESTKSLENTIKELENQINQLNEQNKKQNEQLVQQNQIIAQQDEQINEQTEQ-IT 1863

Query: 1369 NINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIY---QKTHEYTI 1425
             +N +N Q  +              +++    ++ EL  Q++LK+ +I    ++  +   
Sbjct: 1864 QLNLQNNQQNEQIIEQNQQIISQNDKIDQQNEEINELNEQIKLKNEQINKLDEQIKQLEE 1923

Query: 1426 TLTQRNDEFENVRQQLVEYEKRIED---LTYEKESELAILRLKMHENANHYETMQKESEI 1482
             L Q N + +     L EY+ ++ D   L YE++ +L +   +    +N  +  ++ S I
Sbjct: 1924 VLNQLNSQIKQKDLDL-EYKNQLFDNLKLQYEEQGQL-LHNHQEKLKSNTIKLDEQNSMI 1981

Query: 1483 -ERVKLIEELNVKITESV-----SLNKQ---VAELNKALEEEVAKTNEMQTALENQEIEI 1533
             E  +LI +L  ++  S+     SLN+Q   + +LN  L +      ++Q  +   + E 
Sbjct: 1982 EENQQLISQLRTQLENSLKENSHSLNEQENSINQLNCELLQMGQDKQQLQGLIHQLKEEN 2041

Query: 1534 VTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDL 1591
              LN+++    N++  S   I++    A + KQ    QL     +E + ++ + + +L
Sbjct: 2042 SNLNEDLKQKLNIISESQQLIKEKSDIAEELKQNLTNQLQK--QQEYIQSIQQLQEEL 2097



 Score =  135 bits (326), Expect = 1e-29
 Identities = 254/1167 (21%), Positives = 511/1167 (43%), Gaps = 148/1167 (12%)

Query: 523  NKN-MIKVKSNH-KLKLKQMQKTIDNFSK-VSDSNKEIVRLTEELHHLSQKVAELEEEKG 579
            N+N M+K ++ + KLK+++ +K I    + V D++    +L EE     Q + E E ++ 
Sbjct: 689  NENRMLKQENEYLKLKIERCEKEIKEKKRIVEDNDAYYKKLFEEKVEGIQVLRE-ENKQL 747

Query: 580  NLQLH---LVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQK 636
             LQ+H   L  YD  + ++  +Y+ + E ++  E +     L + ++ D       L Q 
Sbjct: 748  QLQIHNLELKSYDKKKNLQK-LYRIITEKDD--ENKKLKYQLQQKEQIDRES----LNQA 800

Query: 637  YDEVEDKLADISQLQSDQVCSE---IKSVHLEEQIDALSASKKELALVIENLKLDKEQLY 693
               +E++L    QL  + +  +   I+++ +    D +  ++K     I N+  ++++  
Sbjct: 801  IQSIEEQLNQKMQLFIEDLAYKERIIENLQVNLFYDNIIQNEKMRGEQINNVFQNQQETE 860

Query: 694  GTIKD----LENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQT 749
              I D    L   +ED+++ LQN    +    +  ++ +   I ELL  I+ E +++IQ 
Sbjct: 861  QPISDKLIELRQKREDLLSILQNNNNYDQYGNENEQQQNLNDIKELLGFIDQEIENEIQF 920

Query: 750  QFGIDAKIQ-------ERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQL 802
               I+ + +       ++ ++ ++I + L +   +  +  +  +++E ++Y+ E    QL
Sbjct: 921  LNNINQQQKQEVDNQNDQQVFAQDIPTSLKEQLQKEIQQLKDQSILELQQYN-EEVIQQL 979

Query: 803  GSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENK--ELQKKNQILLE 860
             + L E      E     D+   R+ + + H R    Q L+ E  NK  EL+KK  I  +
Sbjct: 980  KNILNE------EELDNIDDGFERIQIKLQHAR----QELDQEQANKIIELEKKLLIKQD 1029

Query: 861  ENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLES---NLKRITHEHQTL 917
            E   L+  + ++QQ    LV+K N+    ++ S K Q Q +D  +   +    T E Q L
Sbjct: 1030 ETGRLESQIKELQQ----LVKKQNK----QNSSPKIQNQQQDSRNYTVSAAVETEEDQKL 1081

Query: 918  IVQKKKEIEDLEIEF---NTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENL 974
            I   + +I+ L+ E    NT       D K    + E   +    LE Q Q  + NI+ L
Sbjct: 1082 INSLQNQIQKLKQEIQKANTDFNIIKDDNKSFVSQIEILKKQNQLLETQNQNVQKNIQTL 1141

Query: 975  NMNVEELNKMNLEL------IDKHVQKQQTQ----SPDYTEQYINEINKLN----ALLKQ 1020
               ++ LN+ N  L      I K++Q Q+TQ    S D   Q+ NE NKL      +L++
Sbjct: 1142 EQTIKTLNEQNKSLQKEKESISKNLQ-QKTQNLAKSEDQVAQFKNE-NKLYQEKCGILEK 1199

Query: 1021 KDEEI------------------IALNQKINNAQVSYMSMVSDYE---SKLAQFTTKLEN 1059
            + +E+                     NQ     Q      + D E     L ++  K   
Sbjct: 1200 RIKELEETKKKSSTPSAGTSPNSKGKNQNTQQQQQQLQQYIKDCEQLKQLLIEYEQKFLE 1259

Query: 1060 MEEEMQRVSKQLLDSKQHNEELQILVREQDDQ---IKELKETKLTFEMNIPKTE---GMI 1113
             EE+  ++  ++ D K   EE   ++++Q+++   IK+  +   +F     K E    + 
Sbjct: 1260 KEEDKSKLLAEIEDLKSKLEEAVTIIKQQEEENGKIKQNNQNSTSFLKEKLKEEIEQNLK 1319

Query: 1114 ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYT 1173
                +E   +D  N               K QE +E I + + L E   +   E+++C  
Sbjct: 1320 RVKDLEKEKEDIANEQQDKIELYQNSLSEKQQEIDELISKNNNLNELIDQYQREIKKCKE 1379

Query: 1174 KIIQLETLNTELTGHDVVN-QEQINQLKSKLEQLNTEN-------DNLLSTVAELRSSIS 1225
            K+ +++ +  ++      N Q+Q+ Q    +E +  ++       + L   + EL+  + 
Sbjct: 1380 KMEEIKKMQEKVNLDQQKNMQDQLAQKNKLIEMMKNDSLDDKEEIELLKQEIEELKQQLQ 1439

Query: 1226 SA----------------VDQRGFEIAELWKQH---LAQREAD-FQKTEHELRVQLSAFE 1265
            +                   Q+  E  +L KQ    +A+ E D  QK E E   +++  +
Sbjct: 1440 ATQSKPLSSSRQESQYKEFQQKEEEFKKLIKQQNEKIAKMEQDCLQKMEFE--EEIARLQ 1497

Query: 1266 SKYEQLLDSVQSSTQEET---NKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEI 1322
             + +  LDS   S +++    ++I+  + +  LQNK ++++    +LQE+  ++  +   
Sbjct: 1498 QELQSALDSHNDSGKKQNQSIDQIINDQDIDGLQNK-RNQQNSFEDLQERVKELEEENND 1556

Query: 1323 LRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINE--ENAQLKKS 1380
            LR EI++E+                    L++  +   Q  +++ ++  +  +N Q +  
Sbjct: 1557 LR-EIQNERDCLQQQIQEIIDKNKEETDQLQSTVRLLTQQIQKNQIDSEKIIQNLQNEIG 1615

Query: 1381 SXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQ 1440
            S            +  +AE    E+  +  +K+ + Y  T    I   Q  D+ +    Q
Sbjct: 1616 SMTQFIKQQEQLIQQQNAEHDQKEIEFRQIIKEKDNYIFTQRDQI--EQITDQIKEKNNQ 1673

Query: 1441 LVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVS 1500
            L++ ++ IE+L    E +L I   ++  N+N    +Q E+ +++++  EE   + +    
Sbjct: 1674 LIQMQENIEELKQNYEQQLQINNDQI-SNSNQNFQIQIEN-LQKLR-EEEEKYQNSNLSD 1730

Query: 1501 LNKQVAELNKAL---EEEVAKTNEMQTAL-ENQEIEIVTLND---EITNLQNMVRASSSK 1553
            LN Q+ ELN+AL   EEE+ + N  Q+ + ++ E +I  L     +I   +  ++   S+
Sbjct: 1731 LNNQIQELNQALSQKEEELQEINMKQSVIQQSYENKIKELEQNCLQIFEQKEELQIRISQ 1790

Query: 1554 IQKHVS-FASDTKQGRDEQLDNTMNKE 1579
            + + ++   S  K+  +EQ ++T + E
Sbjct: 1791 LDEEIADLKSVEKKSFEEQTESTKSLE 1817



 Score =  109 bits (263), Expect = 5e-22
 Identities = 206/970 (21%), Positives = 415/970 (42%), Gaps = 82/970 (8%)

Query: 146  HLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXX 205
            +L NT+ E DNAL   + +   +E TI  L +KI    QI    N               
Sbjct: 3389 NLQNTLNECDNALIQERNERATVEETINLLNDKITNL-QIEREDNLEIIEKLKADLLQSQ 3447

Query: 206  XXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARF 265
                     K  + +      +  A+ +   Q    + E  D +I+ LE   K  +  + 
Sbjct: 3448 PQKQNSSPIKLSLPQTSSQAGSSSAQKQQIDQLTFANAELLD-QINELELEIKEYQREKE 3506

Query: 266  EISLEHSKLAQELE--------QXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSL- 316
            EI  E+ KL +E+E        Q              + ++  + + E++ + +++ SL 
Sbjct: 3507 EILDENDKLTKEIELLKGLQGEQPVNRKVELIEDREIMEQELQQLNQEQQVQKQKRASLQ 3566

Query: 317  -EIANMTE-LTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKS 374
             E++++   L + I +++ L  +I    K+L  K  ++  +  A    S++ S +     
Sbjct: 3567 NEMSDLKSILEQNIVVIQTLEEEIVNYKKKLAEKEESLQLKQVANDQNSERFSKIEEELD 3626

Query: 375  -GRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDT 433
              ++    +K+  +QL  +   +D   +   N I +L  +I+       D E + + K  
Sbjct: 3627 ISKHENQNLKNQITQLEQQLSEKDYHLEQQHNSICELSAMIEKFENQKSDAEVIENLKQM 3686

Query: 434  XXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEI 493
                        +  +A    E +Q       I+   N E    I+  +++ K  + +  
Sbjct: 3687 HTDKMKKLVKEHNEALASKDKEIKQLTSLIKNINE-VNEEQNKTISSFEQKHKSLIAERF 3745

Query: 494  KDVN-VKDLIEKLKSAEEQIT---QLNDEIDAANKNMIKVKS--NHKL-----KLKQMQK 542
            +  N +++L + L+  EEQI    + NDE+ A  ++ +K +   N +L     KL   Q 
Sbjct: 3746 ELQNTIQELKDSLQQKEEQIQLFEKKNDEMQAETQDTLKQQKELNQQLETLKEKLSHFQT 3805

Query: 543  TIDNFSKVSDSNKEIV------RLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIES 596
             + N S+   S ++ +      R  +++  L +++ +   EK  L+        G   E 
Sbjct: 3806 NMTNPSEKLSSEEDAIGYQSAKRYEDQIRELQEEIQKRTREKEQLRTEKEIECIGLKQEM 3865

Query: 597  DVYKKMIE-MENLAETRLKAISLLESQKFDLVQELHILQQKYDEV----EDKLADISQLQ 651
            D  +K+ + +    E++ +   +LE  K D +Q+L+  ++K  E+    E+   +I QL+
Sbjct: 3866 DRLQKLCDRLTEQEESQKQLKEVLEDHKNDAIQKLNKEKEKNKEMKKYLEEAHQEIEQLR 3925

Query: 652  SDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTI---KDLENDKEDIMN 708
             ++     K    +     LS+ + E   V +  K  +E+L   +   K LE+  + + +
Sbjct: 3926 KNRHEKHEKDGDNDHHQRKLSSKEDEEDAVYQKYKELEEKLTKILTEKKQLEDQNKSLQS 3985

Query: 709  KLQNY-IQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENI 767
            +LQN  I +N    +   K+   K  EL  KI  E+Q +I     ++  + E +L + ++
Sbjct: 3986 ELQNKSIYDNESFYEFQNKLLKSK-QELEDKIELEQQLEIC----LERLVNEGELDLMDL 4040

Query: 768  ESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRL 827
             +      SRIC              +L +       + Q K+K  S++   +DEL    
Sbjct: 4041 NN------SRICN-------------NLVKIQQNFKEFYQFKEKFGSKH---QDELKKIA 4078

Query: 828  AVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQ--ISLSDMQQHYNALVEKANR 885
                    V EKQ+ E++ + KE+  K  +  EEN++      +   Q+  ++  +   +
Sbjct: 4079 QTYQSQLIVKEKQIKELQ-KYKEMYLKPVLNSEENRDPFNCTKIKIQQKELHSRPDTGRK 4137

Query: 886  TDLAESESTKY-QTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKK 944
            ++++  +  +  + Q+ ++ES LK      ++ I Q K+E+ED E   N  +    R  K
Sbjct: 4138 SEMSNGQKDEQLEYQMLEIES-LKNENILLKSEIDQLKQELEDNEQIQNNFMAEQRRKNK 4196

Query: 945  VLNEKYEKNIEYVTQLEAQLQEYKN--NIENLNMNVEELNKMNLELIDKHVQKQQTQSPD 1002
             L EK +K  E ++Q   Q  +  N  N+ + N+N  E+ KM  ++  K    QQ QS  
Sbjct: 4197 ELQEKEQKIQELISQQNQQKIQSSNRLNMSSSNLN-SEVTKMRQQMEHKDKLIQQLQSQI 4255

Query: 1003 YTEQYINEINKLNALLKQKDEEII-ALNQKINNAQVSYMSMVSDYESKLAQFTTKLEN-M 1060
               Q  +  + L AL     + ++ + ++KI+    SY++++ +    + +++ K +N +
Sbjct: 4256 NVTQDSSIKHSLKALFPTYIDSLLNSKDKKISQENDSYLTLILN----MLEYSEKEKNEI 4311

Query: 1061 EEEMQRVSKQ 1070
            +++M +   Q
Sbjct: 4312 KQKMDKAKNQ 4321



 Score = 94.7 bits (225), Expect = 2e-17
 Identities = 137/692 (19%), Positives = 288/692 (41%), Gaps = 54/692 (7%)

Query: 918  IVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMN 977
            I +KK+ +ED +  +    E  +   +VL E+ ++    +  LE +  + K N++ L   
Sbjct: 712  IKEKKRIVEDNDAYYKKLFEEKVEGIQVLREENKQLQLQIHNLELKSYDKKKNLQKLYRI 771

Query: 978  VEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQV 1037
            + E +  N +L  +  QK+Q       +   +   +LN  ++   E++    + I N QV
Sbjct: 772  ITEKDDENKKLKYQLQQKEQIDRESLNQAIQSIEEQLNQKMQLFIEDLAYKERIIENLQV 831

Query: 1038 S--YMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKEL 1095
            +  Y +++ + + +  Q     +N +E  Q +S +L++ +Q  E+L  +++  ++  +  
Sbjct: 832  NLFYDNIIQNEKMRGEQINNVFQNQQETEQPISDKLIELRQKREDLLSILQNNNNYDQYG 891

Query: 1096 KETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERS 1155
             E +    +N  K     I   IE      NN++               Q++++ +  ++
Sbjct: 892  NENEQQQNLNDIKELLGFIDQEIENEIQFLNNIN---------------QQQKQEVDNQN 936

Query: 1156 VLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKL--EQLNTENDNL 1213
              Q  +  + T L+E   K IQ +  +  +      N+E I QLK+ L  E+L+  +D  
Sbjct: 937  DQQVFAQDIPTSLKEQLQKEIQ-QLKDQSILELQQYNEEVIQQLKNILNEEELDNIDDGF 995

Query: 1214 LSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLD 1273
                 +L+ +      ++  +I EL K+ L +++   +       +Q    +   +    
Sbjct: 996  ERIQIKLQHARQELDQEQANKIIELEKKLLIKQDETGRLESQIKELQQLVKKQNKQNSSP 1055

Query: 1274 SVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVA 1333
             +Q+  Q+  N  V+    T    KL +    L+N  +K    I +     + I+D+  +
Sbjct: 1056 KIQNQQQDSRNYTVSAAVETEEDQKLINS---LQNQIQKLKQEIQKANTDFNIIKDDNKS 1112

Query: 1334 FXXXXXXXXXXXXXXXXDLRTENQSYK---QMQEQSILNINEENAQLKKSSXXXXXXXXX 1390
            F                 L T+NQ+ +   Q  EQ+I  +NE+N  L+K           
Sbjct: 1113 FVSQIEILKKQNQL----LETQNQNVQKNIQTLEQTIKTLNEQNKSLQKEKESISKNLQQ 1168

Query: 1391 XXXRVNDAEAKVLELTHQ----------LELKDSEIYQKTHEYTITLTQRNDEFENVRQQ 1440
                +  +E +V +  ++          LE +  E+ +   + +      +   +   Q 
Sbjct: 1169 KTQNLAKSEDQVAQFKNENKLYQEKCGILEKRIKELEETKKKSSTPSAGTSPNSKGKNQN 1228

Query: 1441 LVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKL---IEELNVKITE 1497
              + +++++   Y K+ E      ++ +    YE    E E ++ KL   IE+L  K+ E
Sbjct: 1229 TQQQQQQLQQ--YIKDCE------QLKQLLIEYEQKFLEKEEDKSKLLAEIEDLKSKLEE 1280

Query: 1498 SVSLNKQVAELNKALEEEVAKTNEMQTALENQEIE--IVTLNDEITNLQNMVRASSSKIQ 1555
            +V++ KQ  E N  +++    +         +EIE  +  + D     +++      KI+
Sbjct: 1281 AVTIIKQQEEENGKIKQNNQNSTSFLKEKLKEEIEQNLKRVKDLEKEKEDIANEQQDKIE 1340

Query: 1556 KHVSFASDTKQGRDEQLDNTMN-KELLDAVPR 1586
             + +  S+ +Q  DE +    N  EL+D   R
Sbjct: 1341 LYQNSLSEKQQEIDELISKNNNLNELIDQYQR 1372



 Score = 76.6 bits (180), Expect = 5e-12
 Identities = 186/1005 (18%), Positives = 404/1005 (40%), Gaps = 84/1005 (8%)

Query: 147  LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXX 206
            L   ++++     +L  K +  +  + +  + + +++  +  +N+ +             
Sbjct: 3235 LQEELQKQIEGNHILSQKQQEEKDLVSENSQNLQQQNLDLHKENEESKAKIQQMKEKLSQ 3294

Query: 207  XXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFE 266
                 E       K QE    M  E + E +   K+I+   V+I  LE   +        
Sbjct: 3295 LEEQIEKVNDDKQKSQEENEKMRIEKETEIEEKEKEIQKLKVQIQDLEGVMEEQTQQIQT 3354

Query: 267  ISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTK 326
             ++E  K  ++L++              + KQ  E     +  + E  +  I    E   
Sbjct: 3355 ANVEVEKFKKDLDERYNQIAFLED----ILKQLEEEKNNLQNTLNECDNALIQERNERAT 3410

Query: 327  KIELLEHLNCQI------RQTNKELENKLATMGTES---KAVSSPSKKGSPLISRKSGRN 377
              E +  LN +I      R+ N E+  KL     +S   K  SSP K   P  S ++G +
Sbjct: 3411 VEETINLLNDKITNLQIEREDNLEIIEKLKADLLQSQPQKQNSSPIKLSLPQTSSQAGSS 3470

Query: 378  TASKMK-SPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVIS--EKDTX 434
            +A K +    +  ++E L+Q  + ++   E  + +  I   N  L  +  ++   + +  
Sbjct: 3471 SAQKQQIDQLTFANAELLDQINELELEIKEYQREKEEILDENDKLTKEIELLKGLQGEQP 3530

Query: 435  XXXXXXXXXGKDTLIAQLQ-LEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEI 493
                      ++ +  +LQ L  +Q ++      +     D+  I +    + Q L +EI
Sbjct: 3531 VNRKVELIEDREIMEQELQQLNQEQQVQKQKRASLQNEMSDLKSILEQNIVVIQTLEEEI 3590

Query: 494  KDVNVKDLIEKLKSAE----------EQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKT 543
             +   K L EK +S +          E+ +++ +E+D +      +K+      +Q+ + 
Sbjct: 3591 VNYK-KKLAEKEESLQLKQVANDQNSERFSKIEEELDISKHENQNLKNQITQLEQQLSEK 3649

Query: 544  IDNFSKVSDSNKEIVRLTEELHHL---SQKVAELEEEKGNLQLHLVDYDSGRMIESDVYK 600
              +  +  +S  E+  + E+  +    ++ +  L++   +    LV   +  +   D   
Sbjct: 3650 DYHLEQQHNSICELSAMIEKFENQKSDAEVIENLKQMHTDKMKKLVKEHNEALASKDKEI 3709

Query: 601  KMI-----EMENLAETRLKAISLLE-------SQKFDL---VQELH-ILQQKYDEVE--D 642
            K +      +  + E + K IS  E       +++F+L   +QEL   LQQK ++++  +
Sbjct: 3710 KQLTSLIKNINEVNEEQNKTISSFEQKHKSLIAERFELQNTIQELKDSLQQKEEQIQLFE 3769

Query: 643  KLADISQLQSDQVCSEIKSVH--LEEQIDALSASKKELALVIENLKLDKEQL-YGTIKDL 699
            K  D  Q ++     + K ++  LE   + LS  +  +    E L  +++ + Y + K  
Sbjct: 3770 KKNDEMQAETQDTLKQQKELNQQLETLKEKLSHFQTNMTNPSEKLSSEEDAIGYQSAKRY 3829

Query: 700  ENDKEDIMNKLQNYIQENMDLTDKLE------KMSAEKISELLAKINHEEQSKIQTQFGI 753
            E+   ++  ++Q   +E   L  + E      K   +++ +L  ++  +E+S+ Q +  +
Sbjct: 3830 EDQIRELQEEIQKRTREKEQLRTEKEIECIGLKQEMDRLQKLCDRLTEQEESQKQLKEVL 3889

Query: 754  DAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAY 813
            +     ++  I+ +  E  K K     LEE+   +E  R +   K ++ G     ++K  
Sbjct: 3890 E---DHKNDAIQKLNKEKEKNKEMKKYLEEAHQEIEQLRKNRHEKHEKDGDNDHHQRKLS 3946

Query: 814  SEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENK----ELQKKNQILLEENQNLQISL 869
            S+   +ED +  +   L +    +  +  ++E +NK    ELQ K+    E     Q  L
Sbjct: 3947 SKED-EEDAVYQKYKELEEKLTKILTEKKQLEDQNKSLQSELQNKSIYDNESFYEFQNKL 4005

Query: 870  SDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLE 929
               +Q     +E   + ++   E    + +L  ++ N  RI + +   I Q  KE    +
Sbjct: 4006 LKSKQELEDKIELEQQLEIC-LERLVNEGELDLMDLNNSRICN-NLVKIQQNFKEFYQFK 4063

Query: 930  IEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELI 989
             +F ++ +  +   K + + Y+  +    +   +LQ+YK       +N EE N+      
Sbjct: 4064 EKFGSKHQDEL---KKIAQTYQSQLIVKEKQIKELQKYKEMYLKPVLNSEE-NRDPFNCT 4119

Query: 990  DKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEI---IALNQKINNAQVSYMSMVSDY 1046
               +Q+++  S   T +     N       QKDE++   +   + + N  +   S +   
Sbjct: 4120 KIKIQQKELHSRPDTGRKSEMSNG------QKDEQLEYQMLEIESLKNENILLKSEIDQL 4173

Query: 1047 ESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQ 1091
            + +L        N   E +R +K+L + +Q   ++Q L+ +Q+ Q
Sbjct: 4174 KQELEDNEQIQNNFMAEQRRKNKELQEKEQ---KIQELISQQNQQ 4215


>UniRef50_Q54G05 Cluster: Putative uncharacterized protein; n=1;
            Dictyostelium discoideum AX4|Rep: Putative
            uncharacterized protein - Dictyostelium discoideum AX4
          Length = 1492

 Score =  195 bits (475), Expect = 1e-47
 Identities = 273/1356 (20%), Positives = 592/1356 (43%), Gaps = 99/1356 (7%)

Query: 147  LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKN----KATTXXXXXXXX 202
            L   IK KDN +  L+ K+K +     + +++  EK++  E +     + TT        
Sbjct: 123  LDGLIKTKDNDIIKLREKIKHLNEKHQESEKRYQEKEKKFEEQRTIEIQETTKKEQEIKS 182

Query: 203  XXXXXXXXXEDTK---QQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKL 259
                     E  K   +Q+ K+ +     E E   +   +LK +  K   I  +E  N  
Sbjct: 183  LTLQLSSKDESMKSLEKQVEKLVDIEHRSEIEQTKKDNEILK-LTEKIKEIQLIENLNST 241

Query: 260  LEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEE-KTEIEEKGSLEI 318
             ++   ++  ++ K  QE                   KQ  E    + + EI++K + E+
Sbjct: 242  NDSKVNQLLEDNIKRLQESLNEIKDENNDLQSLIDTQKQQFEKRINQYQLEIQDKEN-EL 300

Query: 319  ANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNT 378
              M +  + +  ++     ++Q+  +LEN      T+ + V++  +    ++  K     
Sbjct: 301  NEMNQ--QSLSQVKSFQQSLQQSQLDLENDKNQFSTKLQLVNNEIQSLKSIVDDK----- 353

Query: 379  ASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXX 438
              +++   +QL+      + D   N   I +L   I  ++  L +K+  I E        
Sbjct: 354  LKEIQLKDNQLTQLNQQHEIDNNKNNQMILELNDNISKISNQLNEKDNKIQELSKQSIDK 413

Query: 439  XXXXXGKDTLIAQLQLE----HQQHMEGPSLIHVGTN--TEDVNEIAKVQEQLKQELNDE 492
                    +   QLQL+      + +E  + I+  +N   +  N+I ++  +L ++ N  
Sbjct: 414  QKEIENSTSSSDQLQLKLNDISNELLEKLNDINQLSNKLQDKENQILEINNKLNEKENQL 473

Query: 493  I-KDVNVKDLIEKLKSAEEQ----ITQLNDEIDAANKNMI---KVKSNHKLKLKQMQKTI 544
            I KD  +  LIE  +S+ ++    + QL+DE+   ++ ++    V +  +  L + Q  I
Sbjct: 474  ISKDNQLNQLIENNESSSDELKLKLNQLSDELQEKDEKLLNNQSVINELQSNLNENQNKI 533

Query: 545  DNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSG-RMIESDVYKKMI 603
            +   + + S+ + ++L  +L+ LS K+ E +E+  +L+  +++ D     ++ ++ +K  
Sbjct: 534  NELIENNQSSSDELKL--KLNQLSDKLQEKDEKLKSLESSIIERDEKIDQLQDNLNEKQD 591

Query: 604  EMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVH 663
            ++  L E    +   L+S+   L+Q    LQ+K +++ +  + I++LQS+   ++ K   
Sbjct: 592  KINELVENNESSSDELQSK---LIQLSDQLQEKDEKLLNNQSIINELQSNLNENQNK--- 645

Query: 664  LEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDK 723
            + E I+   +S  EL   +  L  + +     ++ LE    +  +KL   IQ N    ++
Sbjct: 646  INELIENNQSSSDELNSKLIKLSDELKDKNENVRSLETSIIENQDKLDQLIQSNQVTVNE 705

Query: 724  LEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEE 783
            L+    EK   +   I + + S  + Q  ++ K  E +  IEN +S   + +S++    +
Sbjct: 706  LQSKLNEKEININQLIENNQSSLDELQSKLNEKQNEINQLIENNQSSSDELQSKLNEKHQ 765

Query: 784  SIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRL--AVLMDHDRVV---- 837
             I+ ++ +   L    +     LQ K    S+   ++DE +  L   ++ + +++V    
Sbjct: 766  EISELQSKLNELIENNESSSDELQSKLIQLSDELKEKDEKLKSLDSIIIENQEKLVQLTK 825

Query: 838  --EKQLLEIEHENKELQKKNQILLEENQN----LQISLSDMQQHYNALVE-KANRTDLAE 890
              +  L E++ +  E Q +   L+E NQ+    LQ  L++ Q   N L+E   + +D  +
Sbjct: 826  SNQDSLDELQSKLNEKQNEINELIENNQSSSNELQSKLNEKQNEINLLIENNQSSSDELQ 885

Query: 891  SESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKY 950
            S+  +   ++ +L+S L    ++   L+   +   ++L+ +   Q+   +++K+   + +
Sbjct: 886  SKLNEKHQEINELQSKLNEKQNKINELVENNESSSDELQSKL-IQLSDQLQEKENQLKSF 944

Query: 951  EKNI----EYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQ 1006
            E +I    E + QL+++L E +N I+ +  N    N+ +L+ +  ++ ++Q +     E 
Sbjct: 945  ESSIIERDEKLNQLQSKLNEKQNEIDQITEN----NQSSLDELQSNLNEKQNEINQLIEN 1000

Query: 1007 YINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQR 1066
              + +++L + L +K  EI   + KIN    +  S+  D +SK      +LE    ++  
Sbjct: 1001 NQSSLDELQSKLNEKLNEINEKDNKINELIQTNESLSKDQQSKFENLEQELEEKNNKILD 1060

Query: 1067 VSKQLLD-----SKQHNE--ELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIE 1119
            ++ Q++D     S++ NE  +LQ+ + E+D +I+      +     + + E       I 
Sbjct: 1061 LNSQIIDVNHQFSEKENELNQLQLKLIEKDQEIENQNNKIIDINNQLNEKE-----KEIN 1115

Query: 1120 PMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLE 1179
              +D+ NN +            L+   E E   E+  + E++  +N EL+E      +++
Sbjct: 1116 INNDNDNNNEENIQLIEELKEKLQ-DLENELNLEKDTVNEKNDDIN-ELKE------EIK 1167

Query: 1180 TLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELW 1239
             ++ +L+  +    E IN     L ++N + D L+ ++ E  ++    ++++  EI  L 
Sbjct: 1168 LISEKLSEKEQELNEMINDYDESLNEINDQKD-LVKSLNERLTNAHLKINEKDNEIHSLS 1226

Query: 1240 KQHLAQREADF-----QKTEHE-LRVQLSAFESKYE-QLLDSVQ----SSTQEETNKIVT 1288
            K+   + ++       Q +E + L ++ S   S  E QL +S +    SS+  +  ++++
Sbjct: 1227 KEGFNEIQSQLNLITNQLSEKDNLLIEKSQIISDLELQLRESYKERSSSSSLHQQQQMIS 1286

Query: 1289 MEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXX 1348
             +   S    + +KEE +  L+EK   +  Q++ L  +    K                 
Sbjct: 1287 PDLSNSNDELIVEKEEIINELKEKNQQLEQQLQDLCQQFNKNKQENELKCQQLEEENDGW 1346

Query: 1349 XXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQ 1408
              ++ T NQ  K     +  + +E   QL   S             + D   K+  L +Q
Sbjct: 1347 KNEIDTLNQRLKTQSLNTSPDSSELQQQLDIIS-NQELNIKQLEKELQDKSGKIDNLEYQ 1405

Query: 1409 LELKDS----EIYQKTHEYTITLTQRNDEFENVRQQ 1440
            +E  +     +I QKT+E +  L     E + +R++
Sbjct: 1406 VEEMNKQYHIDINQKTNESSEKLQSIQLEIDTIREK 1441



 Score =  182 bits (443), Expect = 7e-44
 Identities = 254/1282 (19%), Positives = 550/1282 (42%), Gaps = 81/1282 (6%)

Query: 305  EEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATM-GTESKAVSSPS 363
            E++ + EE+ ++EI   T+  ++I+ L        ++ K LE ++  +   E ++    +
Sbjct: 157  EKEKKFEEQRTIEIQETTKKEQEIKSLTLQLSSKDESMKSLEKQVEKLVDIEHRSEIEQT 216

Query: 364  KKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVD 423
            KK + ++          K+K    QL  E LN   D K+N+     ++ + +SLN+   +
Sbjct: 217  KKDNEILK------LTEKIKE--IQLI-ENLNSTNDSKVNQLLEDNIKRLQESLNEIKDE 267

Query: 424  KEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQE 483
               + S  DT            +  I Q QLE Q      + +    N + ++++   Q+
Sbjct: 268  NNDLQSLIDTQKQQF-------EKRINQYQLEIQDKENELNEM----NQQSLSQVKSFQQ 316

Query: 484  QLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKT 543
             L+Q   D   D N      KL+    +I  L   +D   K  I++K N   +L Q Q  
Sbjct: 317  SLQQSQLDLENDKN--QFSTKLQLVNNEIQSLKSIVDDKLKE-IQLKDNQLTQLNQ-QHE 372

Query: 544  IDNFSK---VSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYK 600
            IDN      + + N  I +++ +L+    K+ EL ++  + Q  + +  S       +  
Sbjct: 373  IDNNKNNQMILELNDNISKISNQLNEKDNKIQELSKQSIDKQKEIENSTSS---SDQLQL 429

Query: 601  KMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLAD----ISQL-QSDQV 655
            K+ ++ N    +L  I+ L ++  D   ++  +  K +E E++L      ++QL ++++ 
Sbjct: 430  KLNDISNELLEKLNDINQLSNKLQDKENQILEINNKLNEKENQLISKDNQLNQLIENNES 489

Query: 656  CSEIKSVHLEEQIDALSASKKELA---LVIENLKLDKEQLYGTIKDLENDKEDIMNKLQN 712
             S+   + L +  D L    ++L     VI  L+ +  +    I +L  + +   ++L+ 
Sbjct: 490  SSDELKLKLNQLSDELQEKDEKLLNNQSVINELQSNLNENQNKINELIENNQSSSDELKL 549

Query: 713  YIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELS 772
             + +   L+DKL++   EK+  L + I   ++   Q Q  ++ K  + +  +EN ES   
Sbjct: 550  KLNQ---LSDKLQEKD-EKLKSLESSIIERDEKIDQLQDNLNEKQDKINELVENNESSSD 605

Query: 773  KYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYT----IQEDELVNRLA 828
            + +S++ +L + +   +++  + +   ++L S L E Q   +E         DEL ++L 
Sbjct: 606  ELQSKLIQLSDQLQEKDEKLLNNQSIINELQSNLNENQNKINELIENNQSSSDELNSKLI 665

Query: 829  VLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQ----NLQISLSDMQQHYNALVEKAN 884
             L D  +   + +  +E    E Q K   L++ NQ     LQ  L++ + + N L+E  N
Sbjct: 666  KLSDELKDKNENVRSLETSIIENQDKLDQLIQSNQVTVNELQSKLNEKEININQLIEN-N 724

Query: 885  RTDLAESES--TKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRD 942
            ++ L E +S   + Q ++  L  N +  + E Q+ + +K +EI +L+ + N  IE+    
Sbjct: 725  QSSLDELQSKLNEKQNEINQLIENNQSSSDELQSKLNEKHQEISELQSKLNELIENNESS 784

Query: 943  KKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPD 1002
               L  K  +  + + + + +L+   + I      + +L K N + +D+   K   +  +
Sbjct: 785  SDELQSKLIQLSDELKEKDEKLKSLDSIIIENQEKLVQLTKSNQDSLDELQSKLNEKQNE 844

Query: 1003 YTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEE 1062
              E   N  +  N L  + +E+   +N  I N Q S   + S    K  +       + E
Sbjct: 845  INELIENNQSSSNELQSKLNEKQNEINLLIENNQSSSDELQSKLNEKHQEINELQSKLNE 904

Query: 1063 EMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMS 1122
            +  ++++ + +++  ++ELQ  + +  DQ++E +    +FE +I + +   ++     ++
Sbjct: 905  KQNKINELVENNESSSDELQSKLIQLSDQLQEKENQLKSFESSIIERDEK-LNQLQSKLN 963

Query: 1123 DDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLN 1182
            +  N +D            L+    E+  +   +++   + L+    +   K+ ++   +
Sbjct: 964  EKQNEIDQITENNQSSLDELQSNLNEKQNEINQLIENNQSSLDELQSKLNEKLNEINEKD 1023

Query: 1183 TELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQH 1242
             ++      N+      +SK E L  E +   + + +L S I     Q   +  EL +  
Sbjct: 1024 NKINELIQTNESLSKDQQSKFENLEQELEEKNNKILDLNSQIIDVNHQFSEKENELNQLQ 1083

Query: 1243 LAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDK 1302
            L   E D Q+ E++   ++    ++  +    +  +   + N    ++ +  L+ KLQD 
Sbjct: 1084 LKLIEKD-QEIENQ-NNKIIDINNQLNEKEKEININNDNDNNNEENIQLIEELKEKLQDL 1141

Query: 1303 EEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQM 1362
            E  L NL++   D +N+     +E+++E                     L  + Q   +M
Sbjct: 1142 ENEL-NLEK---DTVNEKNDDINELKEE--------------IKLISEKLSEKEQELNEM 1183

Query: 1363 QEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHE 1422
                  ++NE N Q K               ++N+ + ++  L+ +     +EI  + + 
Sbjct: 1184 INDYDESLNEINDQ-KDLVKSLNERLTNAHLKINEKDNEIHSLSKE---GFNEIQSQLNL 1239

Query: 1423 YTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEI 1482
             T  L+++++      Q + + E ++ + +Y++ S  + L  +    +        E  +
Sbjct: 1240 ITNQLSEKDNLLIEKSQIISDLELQLRE-SYKERSSSSSLHQQQQMISPDLSNSNDELIV 1298

Query: 1483 ERVKLIEELNVKITE-SVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEIT 1541
            E+ ++I EL  K  +    L     + NK  +E   K  +++   +  + EI TLN  + 
Sbjct: 1299 EKEEIINELKEKNQQLEQQLQDLCQQFNKNKQENELKCQQLEEENDGWKNEIDTLNQRLK 1358

Query: 1542 NLQNMVRASSSKIQKHVSFASD 1563
                     SS++Q+ +   S+
Sbjct: 1359 TQSLNTSPDSSELQQQLDIISN 1380



 Score =  179 bits (436), Expect = 5e-43
 Identities = 256/1187 (21%), Positives = 520/1187 (43%), Gaps = 93/1187 (7%)

Query: 459  HMEGPSLIHVGTNTEDVNEIAKVQEQLKQELN-DEIKDVNVKDLIEKLKSAEEQITQLND 517
            H+E P  +++     D  EI    E +K  +   EI    V+ L   +K+ +  I +L +
Sbjct: 81   HVEVPGRVYILRAKNDT-EINYWIEGIKDAIKYHEINSSQVQVLDGLIKTKDNDIIKLRE 139

Query: 518  EIDAANKNMIKVKSNHKLKLKQM--QKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELE 575
            +I   N+   + +  ++ K K+   Q+TI+   + +   +EI  LT +L    + +  LE
Sbjct: 140  KIKHLNEKHQESEKRYQEKEKKFEEQRTIE-IQETTKKEQEIKSLTLQLSSKDESMKSLE 198

Query: 576  EEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLES------QKFDLVQE 629
            ++   L    VD +    IE    KK  E+  L E ++K I L+E+       K + + E
Sbjct: 199  KQVEKL----VDIEHRSEIEQT--KKDNEILKLTE-KIKEIQLIENLNSTNDSKVNQLLE 251

Query: 630  LHI--LQQKYDEVEDKLADISQL---QSDQVCSEIKSVHLEEQIDALSASKKELALVIEN 684
             +I  LQ+  +E++D+  D+  L   Q  Q    I    LE Q D  +   +     +  
Sbjct: 252  DNIKRLQESLNEIKDENNDLQSLIDTQKQQFEKRINQYQLEIQ-DKENELNEMNQQSLSQ 310

Query: 685  LKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQ 744
            +K  ++ L  +  DLENDK     KLQ    E       L+ +  +K+ E+  K N  + 
Sbjct: 311  VKSFQQSLQQSQLDLENDKNQFSTKLQLVNNE----IQSLKSIVDDKLKEIQLKDN--QL 364

Query: 745  SKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGS 804
            +++  Q  ID    + +  I  +   +SK  +++   +  I  +  +    +++ +   S
Sbjct: 365  TQLNQQHEIDNN--KNNQMILELNDNISKISNQLNEKDNKIQELSKQSIDKQKEIENSTS 422

Query: 805  YLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQN 864
               + Q   ++ + +  E +N +  L +  +  E Q+LEI   NK  +K+NQ++ ++NQ 
Sbjct: 423  SSDQLQLKLNDISNELLEKLNDINQLSNKLQDKENQILEIN--NKLNEKENQLISKDNQL 480

Query: 865  LQISLSDMQQHYNALVEKANR-TDLAESESTKY---QTQLRDLESNLKRITHEHQTLIVQ 920
             Q+ + + +   + L  K N+ +D  + +  K    Q+ + +L+SNL    ++   LI  
Sbjct: 481  NQL-IENNESSSDELKLKLNQLSDELQEKDEKLLNNQSVINELQSNLNENQNKINELIEN 539

Query: 921  KKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNI----EYVTQLEAQLQEYKNNIENLNM 976
             +   ++L+++ N Q+   +++K    +  E +I    E + QL+  L E ++ I  L  
Sbjct: 540  NQSSSDELKLKLN-QLSDKLQEKDEKLKSLESSIIERDEKIDQLQDNLNEKQDKINEL-- 596

Query: 977  NVEELNKMNLELIDKHVQ-KQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNA 1035
             VE     + EL  K +Q   Q Q  D  E+ +N  + +N L    +E    +N+ I N 
Sbjct: 597  -VENNESSSDELQSKLIQLSDQLQEKD--EKLLNNQSIINELQSNLNENQNKINELIENN 653

Query: 1036 QVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEEL----QILVREQDDQ 1091
            Q    S   +  SKL + + +L++  E ++ +   +++++   ++L    Q+ V E   +
Sbjct: 654  Q----SSSDELNSKLIKLSDELKDKNENVRSLETSIIENQDKLDQLIQSNQVTVNELQSK 709

Query: 1092 IKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFI 1151
            + E KE  +   +   ++    + S +    ++ N +                ++ +E  
Sbjct: 710  LNE-KEININQLIENNQSSLDELQSKLNEKQNEINQLIENNQSSSDELQSKLNEKHQEIS 768

Query: 1152 QERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTEND 1211
            + +S L E      +   E  +K+IQL   + EL       +E+  +LKS L+ +  EN 
Sbjct: 769  ELQSKLNELIENNESSSDELQSKLIQL---SDEL-------KEKDEKLKS-LDSIIIENQ 817

Query: 1212 NLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQL 1271
              L    +L  S   ++D+   ++ E  +  + +   + Q + +EL+ +L+  +++   L
Sbjct: 818  EKL---VQLTKSNQDSLDELQSKLNEK-QNEINELIENNQSSSNELQSKLNEKQNEINLL 873

Query: 1272 LDSVQSSTQEETNKIVTMEQ-VTSLQNKLQDKEEHLRNL---QEKYADVIN----QIEIL 1323
            +++ QSS+ E  +K+    Q +  LQ+KL +K+  +  L    E  +D +     Q+   
Sbjct: 874  IENNQSSSDELQSKLNEKHQEINELQSKLNEKQNKINELVENNESSSDELQSKLIQLSDQ 933

Query: 1324 RSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXX 1383
              E E++  +F                 L  +     Q+ E +  +++E  + L +    
Sbjct: 934  LQEKENQLKSFESSIIERDEKLNQLQSKLNEKQNEIDQITENNQSSLDELQSNLNEKQNE 993

Query: 1384 XXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVE 1443
                       +++ ++K+ E  +++  KD++I +           +  +FEN+ Q+L E
Sbjct: 994  INQLIENNQSSLDELQSKLNEKLNEINEKDNKINELIQTNESLSKDQQSKFENLEQELEE 1053

Query: 1444 YEKRIEDLTY----------EKESELAILRLKMHENANHYETMQKESEIERVKLIEELNV 1493
               +I DL            EKE+EL  L+LK+ E     E  Q    I+    + E   
Sbjct: 1054 KNNKILDLNSQIIDVNHQFSEKENELNQLQLKLIEKDQEIEN-QNNKIIDINNQLNEKEK 1112

Query: 1494 KITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSK 1553
            +I  +   +    E  + +EE   K  +++  L  ++  +   ND+I  L+  ++  S K
Sbjct: 1113 EININNDNDNNNEENIQLIEELKEKLQDLENELNLEKDTVNEKNDDINELKEEIKLISEK 1172

Query: 1554 IQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDLAMYMLHQRD 1600
            + +     ++     DE L+   +++ L       L  A   ++++D
Sbjct: 1173 LSEKEQELNEMINDYDESLNEINDQKDLVKSLNERLTNAHLKINEKD 1219



 Score =  130 bits (313), Expect = 4e-28
 Identities = 202/1050 (19%), Positives = 471/1050 (44%), Gaps = 95/1050 (9%)

Query: 96   NTLKQKEILMEKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKD 155
            N  K    L EK  + +ELSK+S     +               +L D+   SN + EK 
Sbjct: 388  NISKISNQLNEKDNKIQELSKQSIDK--QKEIENSTSSSDQLQLKLNDI---SNELLEKL 442

Query: 156  NALSVLQVKMKIMETTILDLQEKINEKD-QIIEAKNKATTXXXXXXXXXXXXXXXXXEDT 214
            N ++ L  K++  E  IL++  K+NEK+ Q+I   N+                     ++
Sbjct: 443  NDINQLSNKLQDKENQILEINNKLNEKENQLISKDNQLN-------------QLIENNES 489

Query: 215  KQQMTKMQENFIAMEAEWKDEK----QRLLKDIESK-DVRISSLEEANKLLEAARFEISL 269
                 K++ N ++ E + KDEK    Q ++ +++S  +   + + E  +  +++  E+ L
Sbjct: 490  SSDELKLKLNQLSDELQEKDEKLLNNQSVINELQSNLNENQNKINELIENNQSSSDELKL 549

Query: 270  EHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIE 329
            + ++L+ +L++                 + I+   +   E ++K +  + N    + +++
Sbjct: 550  KLNQLSDKLQEKDEKLKSLESSIIE-RDEKIDQLQDNLNEKQDKINELVENNESSSDELQ 608

Query: 330  -LLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQ 388
              L  L+ Q+++ +++L N  + +      ++    K + LI  ++ ++++ ++ S   +
Sbjct: 609  SKLIQLSDQLQEKDEKLLNNQSIINELQSNLNENQNKINELI--ENNQSSSDELNSKLIK 666

Query: 389  LSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTL 448
            LS E   +D ++ +   E + +E      N+D +D+  +I                K+  
Sbjct: 667  LSDEL--KDKNENVRSLETSIIE------NQDKLDQ--LIQSNQVTVNELQSKLNEKEIN 716

Query: 449  IAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEI--KDVNVKDLIEKLK 506
            I QL +E+ Q         +     ++N++ +  +    EL  ++  K   + +L  KL 
Sbjct: 717  INQL-IENNQSSLDELQSKLNEKQNEINQLIENNQSSSDELQSKLNEKHQEISELQSKLN 775

Query: 507  SAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTE-ELH 565
               E     +DE+ +    +I++    K K +++ K++D  S + ++ +++V+LT+    
Sbjct: 776  ELIENNESSSDELQS---KLIQLSDELKEKDEKL-KSLD--SIIIENQEKLVQLTKSNQD 829

Query: 566  HLSQKVAELEEEKGNL-QLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKF 624
             L +  ++L E++  + +L   +  S   ++S + +K  E+  L E    +   L+S+  
Sbjct: 830  SLDELQSKLNEKQNEINELIENNQSSSNELQSKLNEKQNEINLLIENNQSSSDELQSKLN 889

Query: 625  DLVQELHILQQKYDEVEDKLADI---SQLQSDQVCSEIKSV-----HLEEQIDALSASKK 676
            +  QE++ LQ K +E ++K+ ++   ++  SD++ S++  +       E Q+ +  +S  
Sbjct: 890  EKHQEINELQSKLNEKQNKINELVENNESSSDELQSKLIQLSDQLQEKENQLKSFESSII 949

Query: 677  ELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELL 736
            E    +  L+    +    I  +  + +  +++LQ+ + E  +  ++L + +   + EL 
Sbjct: 950  ERDEKLNQLQSKLNEKQNEIDQITENNQSSLDELQSNLNEKQNEINQLIENNQSSLDELQ 1009

Query: 737  AKIN------HEEQSKIQTQFGIDAKI-QERDLYIENIESELSKYKSRICRLEESIAVME 789
            +K+N      +E+ +KI      +  + +++    EN+E EL +  ++I  L   I  + 
Sbjct: 1010 SKLNEKLNEINEKDNKINELIQTNESLSKDQQSKFENLEQELEEKNNKILDLNSQIIDVN 1069

Query: 790  DRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENK 849
             +    E + +QL   L EK         QE E  N   + +++    +++ + I ++N 
Sbjct: 1070 HQFSEKENELNQLQLKLIEKD--------QEIENQNNKIIDINNQLNEKEKEININNDND 1121

Query: 850  ELQKKNQILLEE-NQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLK 908
               ++N  L+EE  + LQ   +++    + + EK +  +  + E      +L + E  L 
Sbjct: 1122 NNNEENIQLIEELKEKLQDLENELNLEKDTVNEKNDDINELKEEIKLISEKLSEKEQELN 1181

Query: 909  RITHEHQTLIVQKKKEIEDLEIEFNTQIESA-IRDKKVLNEKYEKNIEYVTQLEAQLQEY 967
             + +++   +  +  + +DL    N ++ +A ++  +  NE +  + E   ++++QL   
Sbjct: 1182 EMINDYDESL-NEINDQKDLVKSLNERLTNAHLKINEKDNEIHSLSKEGFNEIQSQLNLI 1240

Query: 968  KNNI-ENLNMNVEE---LNKMNLELIDKHVQKQQTQSPDYTEQYINE--INKLNALLKQK 1021
             N + E  N+ +E+   ++ + L+L + + ++  + S    +Q I+    N  + L+ +K
Sbjct: 1241 TNQLSEKDNLLIEKSQIISDLELQLRESYKERSSSSSLHQQQQMISPDLSNSNDELIVEK 1300

Query: 1022 DEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEE-----------MQRVSKQ 1070
            +E I  L +K    +     +   +     +   K + +EEE            QR+  Q
Sbjct: 1301 EEIINELKEKNQQLEQQLQDLCQQFNKNKQENELKCQQLEEENDGWKNEIDTLNQRLKTQ 1360

Query: 1071 LLDSKQHNEELQ---ILVREQDDQIKELKE 1097
             L++   + ELQ    ++  Q+  IK+L++
Sbjct: 1361 SLNTSPDSSELQQQLDIISNQELNIKQLEK 1390



 Score =  105 bits (253), Expect = 8e-21
 Identities = 172/869 (19%), Positives = 379/869 (43%), Gaps = 65/869 (7%)

Query: 144  VTHLSNTIKEKDNALSVL----QVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXX 199
            +  L + + EK + ++ L    +     +++ ++ L +++ EKD+ +             
Sbjct: 579  IDQLQDNLNEKQDKINELVENNESSSDELQSKLIQLSDQLQEKDEKLLNNQSIINELQSN 638

Query: 200  XXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQ--RLLKD--IESKDVRISSLEE 255
                        E+ +    ++    I +  E KD+ +  R L+   IE++D ++  L +
Sbjct: 639  LNENQNKINELIENNQSSSDELNSKLIKLSDELKDKNENVRSLETSIIENQD-KLDQLIQ 697

Query: 256  ANKL----LEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIE 311
            +N++    L++   E  +  ++L +  +                  Q IE +     E++
Sbjct: 698  SNQVTVNELQSKLNEKEININQLIENNQSSLDELQSKLNEKQNEINQLIENNQSSSDELQ 757

Query: 312  EKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLIS 371
             K + +   ++EL  K+  L   N     ++ EL++KL  +  E K      K    +I 
Sbjct: 758  SKLNEKHQEISELQSKLNELIENN---ESSSDELQSKLIQLSDELKEKDEKLKSLDSIII 814

Query: 372  RKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEK 431
                +      KS  +Q S + L    ++K  +NEI +L    QS + +L  K   ++EK
Sbjct: 815  ENQEK-LVQLTKS--NQDSLDELQSKLNEK--QNEINELIENNQSSSNELQSK---LNEK 866

Query: 432  DTXXXXXXXXX-XGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELN 490
                           D L ++L  +HQ+  E  S ++   N   +NE+ +  E    EL 
Sbjct: 867  QNEINLLIENNQSSSDELQSKLNEKHQEINELQSKLNEKQNK--INELVENNESSSDELQ 924

Query: 491  DEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKV 550
             ++  ++     ++L+  E Q+      I   ++ + +++S    KL + Q  ID  ++ 
Sbjct: 925  SKLIQLS-----DQLQEKENQLKSFESSIIERDEKLNQLQS----KLNEKQNEIDQITEN 975

Query: 551  SDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIE--SDVYKKMIEMENL 608
            + S+     L E   +L++K  E+ +   N Q  L +  S ++ E  +++ +K  ++  L
Sbjct: 976  NQSS-----LDELQSNLNEKQNEINQLIENNQSSLDELQS-KLNEKLNEINEKDNKINEL 1029

Query: 609  AETRLKAISLLESQKFD-LVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEE- 666
             +T  +++S  +  KF+ L QEL     K  ++  ++ D++   S++  +E+  + L+  
Sbjct: 1030 IQTN-ESLSKDQQSKFENLEQELEEKNNKILDLNSQIIDVNHQFSEKE-NELNQLQLKLI 1087

Query: 667  QIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEK 726
            + D    ++    + I N   +KE+      D +N+ E+ +  ++   ++  DL ++L  
Sbjct: 1088 EKDQEIENQNNKIIDINNQLNEKEKEININNDNDNNNEENIQLIEELKEKLQDLENELN- 1146

Query: 727  MSAEKISELLAKINH-EEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESI 785
            +  + ++E    IN  +E+ K+ ++  +  K QE +  I + +  L++   +   ++   
Sbjct: 1147 LEKDTVNEKNDDINELKEEIKLISE-KLSEKEQELNEMINDYDESLNEINDQKDLVKSLN 1205

Query: 786  AVMEDRRYSLERKADQLGSYLQEK-QKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEI 844
              + +    +  K +++ S  +E   +  S+  +  ++L  +  +L++  +++    L++
Sbjct: 1206 ERLTNAHLKINEKDNEIHSLSKEGFNEIQSQLNLITNQLSEKDNLLIEKSQIISDLELQL 1265

Query: 845  EHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLE 904
                KE +  +  L ++ Q +   LS+       +VEK    +  + ++ + + QL+DL 
Sbjct: 1266 RESYKE-RSSSSSLHQQQQMISPDLSNSNDEL--IVEKEEIINELKEKNQQLEQQLQDLC 1322

Query: 905  SNLKRITHEHQTLIVQK-------KKEIEDLEIEFNTQIESAIRDKKVLNEKYE--KNIE 955
                +   E++    Q        K EI+ L     TQ  +   D   L ++ +   N E
Sbjct: 1323 QQFNKNKQENELKCQQLEEENDGWKNEIDTLNQRLKTQSLNTSPDSSELQQQLDIISNQE 1382

Query: 956  Y-VTQLEAQLQEYKNNIENLNMNVEELNK 983
              + QLE +LQ+    I+NL   VEE+NK
Sbjct: 1383 LNIKQLEKELQDKSGKIDNLEYQVEEMNK 1411


>UniRef50_A2DDP2 Cluster: Viral A-type inclusion protein, putative;
            n=1; Trichomonas vaginalis G3|Rep: Viral A-type inclusion
            protein, putative - Trichomonas vaginalis G3
          Length = 2120

 Score =  194 bits (473), Expect = 2e-47
 Identities = 300/1496 (20%), Positives = 632/1496 (42%), Gaps = 111/1496 (7%)

Query: 147  LSNTIKEKDNALSVLQVKMKIMETTILDLQEKI----NEKDQIIEAKNKATTXXXXXXXX 202
            L + +KE  +  S L+  MK+++    DL+E+I    N  DQI+E K K           
Sbjct: 506  LRSQLKENKDYQSQLE-NMKLIQEENDDLKERIGDMSNLSDQILELKKKLNDSENEKEIL 564

Query: 203  XXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEA 262
                     +D ++ +      F  + ++ K E Q L K I   + +IS   E  K    
Sbjct: 565  RKQIDNLCKDDEEEDVP----TFSKVISDLKVENQILKKKISDSE-QISKENEDLKKQIN 619

Query: 263  ARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLE--IAN 320
               +I  E+ +L  E+                + KQ+ +          +  +LE  + N
Sbjct: 620  EYIDIENENDELKDEISTLQNNIQKITERNEEIEKQNDDLKKNNDDLHVKIHNLEQKVDN 679

Query: 321  MTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTAS 380
            +T L  ++ + +     I++ N  L+NK A+    S    +   K   L  R     T  
Sbjct: 680  LTNLNNELTINQMKYEDIKEENDLLKNKSAS--PVSATPRTQQNKIQQLQMRNDELKTEI 737

Query: 381  KMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDK--EYVISEKDTXXXXX 438
            ++        +    +D D K   NEI  L+   + LN  L D   + ++ +++      
Sbjct: 738  EILHQTIDKLTSARIKDNDSKTVDNEIDLLKKENERLNAMLDDSSMQIIMLQQEIDENKS 797

Query: 439  XXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELN--DEIKDV 496
                   + L  Q++ E Q+H   P  +    N+    E  K+QE++++  N  D++++ 
Sbjct: 798  NSLKQENEKLQEQIE-ELQKHSPSPKKLQQENNSLK-QENEKLQEEIEELQNTVDKLQNE 855

Query: 497  N-VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNK 555
            N ++ L E+    +++I +L   ++   +   ++K+N  +     +K  +  + +   N+
Sbjct: 856  NNLQSLQEENDKLQDEIEELQSTVEKLQQENEELKNNKPIYSPSPKKLQNENNSLKQENE 915

Query: 556  EIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKA 615
            ++    EEL +   K+    +    LQ      ++    E +  K+ IE  N  +++  +
Sbjct: 916  KLQEQIEELQNTIDKLQNSNKSPNKLQQE----NNSLKQEIENLKEEIEQNN--KSKSYS 969

Query: 616  ISLLESQKFDLVQELHILQQKYDEVEDKLADISQ----LQSDQ-VCSEIKSVHLEEQI-- 668
             + L+++   L QE   LQ++ +E+++ +  + Q    L++++ V    K +  E  +  
Sbjct: 970  PNKLQNENESLKQENEKLQEQIEELQNTVEKLQQENDLLKNNKSVSPSPKKLQQENDLLK 1029

Query: 669  --DALSASKKELALVIENLKLDKEQLYGTIKDLEN--DKEDIMNKLQNYIQ-ENMDLTDK 723
               ++S S K+L     +LK + E+L   I++L+N  DK    NK    +Q EN  + + 
Sbjct: 1030 NNKSVSPSPKKLQNENNSLKQENEKLQEEIEELQNTIDKLQNSNKSPKKLQQENKSMLNS 1089

Query: 724  LEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEE 783
              K+  E   E L + N + Q +I+       K+Q+ +  ++N +S+      +  RL++
Sbjct: 1090 PNKLQNEY--ETLQEENEKLQDEIEELQSTVEKLQQENDLLKNSKSKSVSPSPK--RLQQ 1145

Query: 784  SIAVMEDRRYSLERKADQLGSYLQEKQKAYSE-YTIQEDELVNRLAVLMDHDRVVEKQLL 842
                ++     L+ + +QL + +++ Q   S+ Y+    +L N    L   +  +++Q+ 
Sbjct: 1146 ENNSLKQENEKLQEEINQLQNTIEKLQNNKSKLYSPSPKKLQNENESLKQENEKLQEQIE 1205

Query: 843  EIEHEN----------KELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESE 892
            +++ EN          ++LQ++N  L +EN+ LQ  +  +Q     L ++ N++    + 
Sbjct: 1206 KLQQENDSKPKYSPSPRKLQQENNSLKQENEKLQEEIDQLQNTIEKLQQENNKSKSLLNT 1265

Query: 893  STKYQTQLRDLESNLKRITHEHQTL-IVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYE 951
              K Q +   L+    ++  E + L    +K + E+ E++ N  I S    KK+ NE   
Sbjct: 1266 PNKLQNEYETLQEENDKLQDEIEELQSTVEKLQQENEELKNNKPIYSP-SPKKLQNENNS 1324

Query: 952  KNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLE--LIDKHVQ--KQQTQSPDYTEQY 1007
               E   +L+ +++E +N I+ L  + +  NK+  E   + + ++  K++ +  + ++ Y
Sbjct: 1325 LKQEN-EKLQEEIEELQNTIDKLQNSNKSPNKLQQENNSLKQEIENLKEEIEQNNKSKSY 1383

Query: 1008 I-NEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQR 1066
              N++   N  LKQ++E+   L ++I   Q +   +    E+ L +    +    +++Q 
Sbjct: 1384 SPNKLQNENESLKQENEK---LQEEIEELQNTVEKL--QQENDLLKNNKSVSPSPKKLQN 1438

Query: 1067 VSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDAN 1126
             +  L   KQ NE+LQ  + E  + I +L+ +  +     PK     +    + M +  N
Sbjct: 1439 ENNSL---KQENEKLQEEIEELQNTIDKLQNSNKS-----PKK----LQQENKSMLNSPN 1486

Query: 1127 NVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELT 1186
             +             L+ + EE       + QE     N++ +       +L+  N  L 
Sbjct: 1487 KLQNEYETLQEENEKLQDEIEELQSTVEKLQQENDLLKNSKSKSVSPSPKRLQQENNSLK 1546

Query: 1187 GHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQR 1246
              +   QE+INQL++ +E+L      L S   +   + + ++ Q   ++ E  ++   + 
Sbjct: 1547 QENEKLQEEINQLQNTIEKLQNNKSKLYSPSPKKLQNENESLKQENEKLQEQIEKLQQEN 1606

Query: 1247 EAD---------FQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQN 1297
            ++           Q+  + L+ +    + + +QL ++++   QE       +     LQN
Sbjct: 1607 DSKPKYSPSPRKLQQENNSLKQENEKLQEEIDQLQNTIEKLQQENNKSKSLLNTPNKLQN 1666

Query: 1298 KLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQ 1357
            + +  +E    LQ+K  ++ + IE L+ E E+ K                    L+ EN+
Sbjct: 1667 EYETLQEENDKLQDKIEELQSTIEKLQQENEELK-NNKPIYSPSPKKLQNENNSLKQENE 1725

Query: 1358 SYK-------------QMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLE 1404
              +             Q++ +S   + +EN  LK+                + +  K+ +
Sbjct: 1726 KLQEEIEELQNTIDKLQIENKSPNKLQQENNSLKQEIENLKEEIEQNNKSKSYSPKKLQQ 1785

Query: 1405 LTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRL 1464
              + L+ ++ ++ ++  E   T+ +  +  EN  Q L E   +++D   E +S +  L+ 
Sbjct: 1786 ENNSLKQENEKLQEEIDELQNTVDKLQN--ENNLQSLQEENDKLQDEIEELQSTVEKLQQ 1843

Query: 1465 KMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEE---EVAKTNE 1521
            +  E  N+        +    KL  E N    E+  L +++ EL   +++   E    N+
Sbjct: 1844 ENEELKNNKPIYSPSPK----KLQNENNSLKQENEKLQEEIEELQNTIDKLQIENKSPNK 1899

Query: 1522 MQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMN 1577
            +Q    + + EI  L +EI         S  K+Q+  +      +   E++D   N
Sbjct: 1900 LQQENNSLKQEIENLKEEIEQNNKSKSYSPKKLQQENNSLKQENEKLQEEIDELQN 1955



 Score =  176 bits (429), Expect = 4e-42
 Identities = 307/1387 (22%), Positives = 599/1387 (43%), Gaps = 148/1387 (10%)

Query: 240  LKDIESKDV--RISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAK 297
            +KD +SK V   I  L++ N+ L A   + S++   L QE+++                 
Sbjct: 752  IKDNDSKTVDNEIDLLKKENERLNAMLDDSSMQIIMLQQEIDENKSNSLKQENEKLQEQI 811

Query: 298  QSIEPSCEEKTEIE-EKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTES 356
            + ++       +++ E  SL+  N  +L ++IE L++   +++      EN L ++  E+
Sbjct: 812  EELQKHSPSPKKLQQENNSLKQEN-EKLQEEIEELQNTVDKLQN-----ENNLQSLQEEN 865

Query: 357  KAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQS 416
              +    ++    + +    N   K   P    S + L  + +    +NE  KL+  I+ 
Sbjct: 866  DKLQDEIEELQSTVEKLQQENEELKNNKPIYSPSPKKLQNENNSLKQENE--KLQEQIEE 923

Query: 417  LNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVN 476
            L ++ +DK   +   +                I  L+ E +Q+ +  S           N
Sbjct: 924  L-QNTIDK---LQNSNKSPNKLQQENNSLKQEIENLKEEIEQNNKSKSY--------SPN 971

Query: 477  EIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLK 536
            ++    E LKQE N+++++      IE+L++  E++ Q ND +    KN   V  + K K
Sbjct: 972  KLQNENESLKQE-NEKLQEQ-----IEELQNTVEKLQQENDLL----KNNKSVSPSPK-K 1020

Query: 537  LKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIES 596
            L+Q    + N   VS S K   +L  E + L Q+  +L+EE   LQ + +D    ++  S
Sbjct: 1021 LQQENDLLKNNKSVSPSPK---KLQNENNSLKQENEKLQEEIEELQ-NTID----KLQNS 1072

Query: 597  DVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQ-V 655
            +   K ++ EN  ++ L + + L+++   L +E   LQ   DE+E+  + + +LQ +  +
Sbjct: 1073 NKSPKKLQQEN--KSMLNSPNKLQNEYETLQEENEKLQ---DEIEELQSTVEKLQQENDL 1127

Query: 656  CSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQ 715
                KS  +      L      L    E L+ +  QL  TI+ L+N+K  + +     +Q
Sbjct: 1128 LKNSKSKSVSPSPKRLQQENNSLKQENEKLQEEINQLQNTIEKLQNNKSKLYSPSPKKLQ 1187

Query: 716  -ENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKY 774
             EN  L     K   EK+ E + K+  E  SK +       K+Q+ +    +++ E  K 
Sbjct: 1188 NENESL-----KQENEKLQEQIEKLQQENDSKPKYSPS-PRKLQQEN---NSLKQENEKL 1238

Query: 775  KSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEY-TIQEDELVNRLAVLMDH 833
            +  I +L+ +I         L+++ ++  S L    K  +EY T+QE+        L D 
Sbjct: 1239 QEEIDQLQNTIE-------KLQQENNKSKSLLNTPNKLQNEYETLQEEN-----DKLQDE 1286

Query: 834  DRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESES 893
               ++  + +++ EN+EL+    I     + LQ   + ++Q    L E     ++ E ++
Sbjct: 1287 IEELQSTVEKLQQENEELKNNKPIYSPSPKKLQNENNSLKQENEKLQE-----EIEELQN 1341

Query: 894  TKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKN 953
            T  + Q  +   N  ++  E+ +L    K+EIE+L+ E    IE   + K     K +  
Sbjct: 1342 TIDKLQNSNKSPN--KLQQENNSL----KQEIENLKEE----IEQNNKSKSYSPNKLQNE 1391

Query: 954  IEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINK 1013
             E + Q   +LQE    IE L   VE+L + N +L+  +  K  + SP   +   N + +
Sbjct: 1392 NESLKQENEKLQE---EIEELQNTVEKLQQEN-DLLKNN--KSVSPSPKKLQNENNSLKQ 1445

Query: 1014 LNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLD 1073
             N  L+++ EE+     K+ N+  S   +  + +S L     KL+N  E +Q  +++L D
Sbjct: 1446 ENEKLQEEIEELQNTIDKLQNSNKSPKKLQQENKSMLNS-PNKLQNEYETLQEENEKLQD 1504

Query: 1074 SKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXX 1133
              +  +     +++++D +K  K   ++      + E   +    E + ++ N +     
Sbjct: 1505 EIEELQSTVEKLQQENDLLKNSKSKSVSPSPKRLQQENNSLKQENEKLQEEINQLQNTIE 1564

Query: 1134 XXXXXXXXL------KVQEEEEFI-QERSVLQEQSAKLNTE--LQECYTKIIQ-LETLNT 1183
                    L      K+Q E E + QE   LQEQ  KL  E   +  Y+   + L+  N 
Sbjct: 1565 KLQNNKSKLYSPSPKKLQNENESLKQENEKLQEQIEKLQQENDSKPKYSPSPRKLQQENN 1624

Query: 1184 ELTGHDVVNQEQINQLKSKLEQLNTEND---NLLSTVAELRSSISSAVDQRGFEIAELWK 1240
             L   +   QE+I+QL++ +E+L  EN+   +LL+T  +L++   +  ++      ++  
Sbjct: 1625 SLKQENEKLQEEIDQLQNTIEKLQQENNKSKSLLNTPNKLQNEYETLQEENDKLQDKI-- 1682

Query: 1241 QHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQ 1300
            + L       Q+   EL+     +    ++L +   S  QE       +E++ +  +KLQ
Sbjct: 1683 EELQSTIEKLQQENEELKNNKPIYSPSPKKLQNENNSLKQENEKLQEEIEELQNTIDKLQ 1742

Query: 1301 DKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYK 1360
             + +    LQ++   +  +IE L+ EIE    +                  L+ EN S K
Sbjct: 1743 IENKSPNKLQQENNSLKQEIENLKEEIEQNNKS-----------KSYSPKKLQQENNSLK 1791

Query: 1361 QMQEQSILNINE-ENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQK 1419
            Q  E+    I+E +N   K  +            ++ D   ++     +L+ ++ E+   
Sbjct: 1792 QENEKLQEEIDELQNTVDKLQNENNLQSLQEENDKLQDEIEELQSTVEKLQQENEELKNN 1851

Query: 1420 THEYTITLTQRNDEFENVRQQLVEYEKRIEDL--TYEKES--ELAILRLKMHENANHYET 1475
               Y+ +  +  +E  +++Q+  + ++ IE+L  T +K      +  +L+   N+   E 
Sbjct: 1852 KPIYSPSPKKLQNENNSLKQENEKLQEEIEELQNTIDKLQIENKSPNKLQQENNSLKQEI 1911

Query: 1476 MQKESEIER---------VKLIEELNVKITESVSLNKQVAELN------------KALEE 1514
               + EIE+          KL +E N    E+  L +++ EL             ++L+E
Sbjct: 1912 ENLKEEIEQNNKSKSYSPKKLQQENNSLKQENEKLQEEIDELQNTVDKLQNENNLQSLQE 1971

Query: 1515 EVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKH---VSFASDTKQGRDEQ 1571
            E  K  +    L++   ++   N+E+ N + +   S  K+Q     +   ++  Q   E+
Sbjct: 1972 ENDKLQDEIEELQSTVEKLQQENEELKNNKPIYSPSPKKLQNENNSLKQENEKLQEEIEE 2031

Query: 1572 LDNTMNK 1578
            L NT++K
Sbjct: 2032 LQNTIDK 2038



 Score =  174 bits (424), Expect = 1e-41
 Identities = 302/1446 (20%), Positives = 630/1446 (43%), Gaps = 139/1446 (9%)

Query: 212  EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSL-EEANKLLEAARFEISLE 270
            +D  +   ++QE    +   + D   +  K  E  ++ I+ L +  N+ L+    EI   
Sbjct: 164  DDLSRLNVQLQEKIKLLSTSYTDLSAKFDKQNEDHEIEIAKLIDRQNERLK----EIEES 219

Query: 271  HSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIEL 330
            H    Q+++                 K+ ++ S +E  ++EE   L+     E TK I L
Sbjct: 220  HKSNIQQIQTNKDGLTNQIQQEFTKTKEDLDKSRKEYKQLEE---LQRKAQEENTKTISL 276

Query: 331  LEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLS 390
            L   N QI Q   +LE   +    +  AV    KK    + R +        K    Q  
Sbjct: 277  L---NIQINQLQNQLEKAYSGKQADDVAV----KKNIADLERSNAE------KDVVIQSL 323

Query: 391  SETLNQDTDKKIN-KNEIAKLEMVIQSLNKDLVDKEYVI---SEK-DTXXXXXXXXXXGK 445
            S  + +  +K  N + +I++ E  I+ LN    D +  I   S K D             
Sbjct: 324  STKVGRFEEKVSNLEAKISEYEKTIKQLNNSKEDLQKQINNFSNKIDIERAEKQIYIENN 383

Query: 446  DTLIAQLQ----------LEHQQHMEGPSL--IHVGTNTEDVNEIAKVQEQ---LKQELN 490
            + L  Q+Q           E QQ +E   +  + +  NTE  N I  +QE+   L+Q+L+
Sbjct: 384  NDLKEQIQNDEIKFQKERKEFQQELENLRIKFVQLSNNTEKDNLIQHLQEEINALRQKLS 443

Query: 491  DEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKV 550
            +  K V         +S E  IT L  +I     NM+K+++      ++++K I+N+  +
Sbjct: 444  EYSKIVENSKSTPGKESYESTITNLRTQI-----NMLKLEN------QEIKKDIENYDTM 492

Query: 551  SDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAE 610
               N+E+ +  ++L    ++  + + +  N++L   + D       D+ +++ +M NL++
Sbjct: 493  EKQNEEMKKQMDDLRSQLKENKDYQSQLENMKLIQEEND-------DLKERIGDMSNLSD 545

Query: 611  TRLKAISLLESQKFDLVQELHILQQKYDEV--EDKLADISQLQSDQVCSEIKSVHLEEQI 668
              L+    L+ +  D   E  IL+++ D +  +D+  D+      +V S++K   +E QI
Sbjct: 546  QILE----LKKKLNDSENEKEILRKQIDNLCKDDEEEDVPTF--SKVISDLK---VENQI 596

Query: 669  DALSASKKELALVIENLKLDKE-QLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKM 727
                 S  E  +  EN  L K+   Y  I++  ++ +D ++ LQN IQ+  +  +++EK 
Sbjct: 597  LKKKISDSE-QISKENEDLKKQINEYIDIENENDELKDEISTLQNNIQKITERNEEIEKQ 655

Query: 728  S---AEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENI--ESELSKYKSRICRLE 782
            +    +   +L  KI++ EQ K+     ++ ++    +  E+I  E++L K KS    + 
Sbjct: 656  NDDLKKNNDDLHVKIHNLEQ-KVDNLTNLNNELTINQMKYEDIKEENDLLKNKS-ASPVS 713

Query: 783  ESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYT---IQEDE---LVNRLAVL-MDHDR 835
             +    +++   L+ + D+L + ++   +   + T   I++++   + N + +L  +++R
Sbjct: 714  ATPRTQQNKIQQLQMRNDELKTEIEILHQTIDKLTSARIKDNDSKTVDNEIDLLKKENER 773

Query: 836  ---VVEKQLLEIEHENKEL-QKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAES 891
               +++   ++I    +E+ + K+  L +EN+ LQ  + ++Q+H  +  +     +  + 
Sbjct: 774  LNAMLDDSSMQIIMLQQEIDENKSNSLKQENEKLQEQIEELQKHSPSPKKLQQENNSLKQ 833

Query: 892  ESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYE 951
            E+ K Q ++ +L++ + ++ +E+    +Q++ +    EIE   +++S +   +  NE+ +
Sbjct: 834  ENEKLQEEIEELQNTVDKLQNENNLQSLQEENDKLQDEIE---ELQSTVEKLQQENEELK 890

Query: 952  KNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEI 1011
             N    +    +LQ   N+++  N  ++E  +     IDK   +   +SP+  +Q  N +
Sbjct: 891  NNKPIYSPSPKKLQNENNSLKQENEKLQEQIEELQNTIDK--LQNSNKSPNKLQQENNSL 948

Query: 1012 NKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQL 1071
             +    LK++ E+         N   +    +     KL +   +L+N  E++Q+ +  L
Sbjct: 949  KQEIENLKEEIEQNNKSKSYSPNKLQNENESLKQENEKLQEQIEELQNTVEKLQQENDLL 1008

Query: 1072 LDSKQHNEELQILVREQDDQIKELKET-----KLTFEMNIPKTEGMIISSTIEPMSDDAN 1126
             ++K  +   + L ++++D +K  K       KL  E N  K E   +   IE + +  +
Sbjct: 1009 KNNKSVSPSPKKL-QQENDLLKNNKSVSPSPKKLQNENNSLKQENEKLQEEIEELQNTID 1067

Query: 1127 NVDXXXXXXXXXXXXLK--VQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTE 1184
             +              K  +    +   E   LQE++ KL  E++E  + + +L+  N  
Sbjct: 1068 KLQNSNKSPKKLQQENKSMLNSPNKLQNEYETLQEENEKLQDEIEELQSTVEKLQQENDL 1127

Query: 1185 LTGHDVVN--------QEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIA 1236
            L      +        Q++ N LK + E+L  E + L +T+ +L+++ S        ++ 
Sbjct: 1128 LKNSKSKSVSPSPKRLQQENNSLKQENEKLQEEINQLQNTIEKLQNNKSKLYSPSPKKL- 1186

Query: 1237 ELWKQHLAQREADFQKTEHELRVQLSAFESKYE---QLLDSVQSSTQEETNKIVTMEQVT 1293
            +   + L Q     Q+   +L+ Q +  + KY    + L    +S ++E  K+   E++ 
Sbjct: 1187 QNENESLKQENEKLQEQIEKLQ-QENDSKPKYSPSPRKLQQENNSLKQENEKL--QEEID 1243

Query: 1294 SLQN---KLQDKEEHLRNLQEKYADVINQIEILRSE---IEDEKVAFXXXXXXXXXXXXX 1347
             LQN   KLQ +    ++L      + N+ E L+ E   ++DE                 
Sbjct: 1244 QLQNTIEKLQQENNKSKSLLNTPNKLQNEYETLQEENDKLQDEIEELQSTVEKLQQENEE 1303

Query: 1348 XXXDLRTENQSYKQMQEQSILNINEENAQLK---KSSXXXXXXXXXXXXRVNDAEAKVLE 1404
               +    + S K++Q ++  ++ +EN +L+   +                N  + +   
Sbjct: 1304 LKNNKPIYSPSPKKLQNEN-NSLKQENEKLQEEIEELQNTIDKLQNSNKSPNKLQQENNS 1362

Query: 1405 LTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDL--TYEK---ESEL 1459
            L  ++E    EI Q     + +  +  +E E+++Q+  + ++ IE+L  T EK   E++L
Sbjct: 1363 LKQEIENLKEEIEQNNKSKSYSPNKLQNENESLKQENEKLQEEIEELQNTVEKLQQENDL 1422

Query: 1460 AILRLKMHENANHYETMQKESEIERVKL---IEELNVKITESVSLNKQVAELNKALEEEV 1516
                  +  +    +      + E  KL   IEEL   I +  + NK   +L +  +  +
Sbjct: 1423 LKNNKSVSPSPKKLQNENNSLKQENEKLQEEIEELQNTIDKLQNSNKSPKKLQQENKSML 1482

Query: 1517 AKTNEMQTALENQEIEIVTLNDEITNLQNMV---RASSSKIQKHVSFASDTKQGRDEQLD 1573
               N++Q   E  + E   L DEI  LQ+ V   +  +  ++   S +      R +Q +
Sbjct: 1483 NSPNKLQNEYETLQEENEKLQDEIEELQSTVEKLQQENDLLKNSKSKSVSPSPKRLQQEN 1542

Query: 1574 NTMNKE 1579
            N++ +E
Sbjct: 1543 NSLKQE 1548



 Score =  163 bits (397), Expect = 3e-38
 Identities = 264/1217 (21%), Positives = 529/1217 (43%), Gaps = 100/1217 (8%)

Query: 147  LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXX 206
            L   I+E  N +  LQ   K        LQ++ N   Q IE   +               
Sbjct: 917  LQEQIEELQNTIDKLQNSNKSPNK----LQQENNSLKQEIENLKEEIEQNNKSKSYSPNK 972

Query: 207  XXXXXEDTKQQMTKMQENFIAME--AEWKDEKQRLLKDIESKDVRISSLEEANKLLEAAR 264
                 E  KQ+  K+QE    ++   E   ++  LLK+ +S       L++ N LL+  +
Sbjct: 973  LQNENESLKQENEKLQEQIEELQNTVEKLQQENDLLKNNKSVSPSPKKLQQENDLLKNNK 1032

Query: 265  F------EISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEI 318
                   ++  E++ L QE E+              L   +  P   +K + E K  L  
Sbjct: 1033 SVSPSPKKLQNENNSLKQENEKLQEEIEELQNTIDKLQNSNKSP---KKLQQENKSMLNS 1089

Query: 319  ANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAV-SSPSKKGSPLISRKSGRN 377
             N  +L  + E L+  N +++   +EL++ +  +  E+  + +S SK  SP   R    N
Sbjct: 1090 PN--KLQNEYETLQEENEKLQDEIEELQSTVEKLQQENDLLKNSKSKSVSPSPKRLQQEN 1147

Query: 378  TASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXX 437
             + K ++   Q     L Q+T +K+  N   K ++   S  K   + E +  E +     
Sbjct: 1148 NSLKQENEKLQEEINQL-QNTIEKLQNN---KSKLYSPSPKKLQNENESLKQENEKLQEQ 1203

Query: 438  XXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNT-EDVNEIAKVQEQLKQELNDEIKDV 496
                    D+         +   E  SL        E+++++    E+L+QE N     +
Sbjct: 1204 IEKLQQENDSKPKYSPSPRKLQQENNSLKQENEKLQEEIDQLQNTIEKLQQENNKSKSLL 1263

Query: 497  NVKDLIE-KLKSAEEQITQLNDEIDAANKNMIKVKS-NHKLKLKQMQKTIDNFSKVSDSN 554
            N  + ++ + ++ +E+  +L DEI+     + K++  N +LK  +   +       +++N
Sbjct: 1264 NTPNKLQNEYETLQEENDKLQDEIEELQSTVEKLQQENEELKNNKPIYSPSPKKLQNENN 1323

Query: 555  ---KEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAET 611
               +E  +L EE+  L   + +L+    +    L   ++    E +  K+ IE  N  ++
Sbjct: 1324 SLKQENEKLQEEIEELQNTIDKLQNSNKSPN-KLQQENNSLKQEIENLKEEIEQNN--KS 1380

Query: 612  RLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDAL 671
            +  + + L+++   L QE   LQ++ +E+++ +  + Q   + +    KSV         
Sbjct: 1381 KSYSPNKLQNENESLKQENEKLQEEIEELQNTVEKLQQ--ENDLLKNNKSV--------- 1429

Query: 672  SASKKELALVIENLKLDKEQLYGTIKDLEN--DKEDIMNKLQNYIQ-ENMDLTDKLEKMS 728
            S S K+L     +LK + E+L   I++L+N  DK    NK    +Q EN  + +   K+ 
Sbjct: 1430 SPSPKKLQNENNSLKQENEKLQEEIEELQNTIDKLQNSNKSPKKLQQENKSMLNSPNKLQ 1489

Query: 729  AEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVM 788
             E   E L + N + Q +I+       K+Q+ +  ++N +S+      +  RL++    +
Sbjct: 1490 NEY--ETLQEENEKLQDEIEELQSTVEKLQQENDLLKNSKSKSVSPSPK--RLQQENNSL 1545

Query: 789  EDRRYSLERKADQLGSYLQEKQKAYSE-YTIQEDELVNRLAVLMDHDRVVEKQLLEIEHE 847
            +     L+ + +QL + +++ Q   S+ Y+    +L N    L   +  +++Q+ +++ E
Sbjct: 1546 KQENEKLQEEINQLQNTIEKLQNNKSKLYSPSPKKLQNENESLKQENEKLQEQIEKLQQE 1605

Query: 848  N----------KELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQ 897
            N          ++LQ++N  L +EN+ LQ  +  +Q     L ++ N++    +   K Q
Sbjct: 1606 NDSKPKYSPSPRKLQQENNSLKQENEKLQEEIDQLQNTIEKLQQENNKSKSLLNTPNKLQ 1665

Query: 898  TQLRDLESNLKRITHEHQTL-IVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEY 956
             +   L+    ++  + + L    +K + E+ E++ N  I S    KK+ NE      E 
Sbjct: 1666 NEYETLQEENDKLQDKIEELQSTIEKLQQENEELKNNKPIYSP-SPKKLQNENNSLKQEN 1724

Query: 957  VTQLEAQLQEYKNNIENLNMNVEELNKMNLE--LIDKHVQ--KQQTQSPDYTEQYI-NEI 1011
              +L+ +++E +N I+ L +  +  NK+  E   + + ++  K++ +  + ++ Y   ++
Sbjct: 1725 -EKLQEEIEELQNTIDKLQIENKSPNKLQQENNSLKQEIENLKEEIEQNNKSKSYSPKKL 1783

Query: 1012 NKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQL 1071
             + N  LKQ++E++     ++ N  V  +   ++ +S L +   KL++  EE+Q   ++L
Sbjct: 1784 QQENNSLKQENEKLQEEIDELQNT-VDKLQNENNLQS-LQEENDKLQDEIEELQSTVEKL 1841

Query: 1072 LDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXX 1131
               +Q NEEL+      +  I      KL  E N  K E   +   IE +    N +D  
Sbjct: 1842 ---QQENEELK-----NNKPIYSPSPKKLQNENNSLKQENEKLQEEIEELQ---NTIDKL 1890

Query: 1132 XXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVV 1191
                       K+Q+E   +++     ++  + N + +    K +Q E  N  L   +  
Sbjct: 1891 QIENKSPN---KLQQENNSLKQEIENLKEEIEQNNKSKSYSPKKLQQE--NNSLKQENEK 1945

Query: 1192 NQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQ 1251
             QE+I++L++ +++L  EN NL         S+    D+   EI EL  Q   ++    Q
Sbjct: 1946 LQEEIDELQNTVDKLQNEN-NL--------QSLQEENDKLQDEIEEL--QSTVEK---LQ 1991

Query: 1252 KTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQE 1311
            +   EL+     +    ++L +   S  QE       +E++ +  +KLQ + +    LQ+
Sbjct: 1992 QENEELKNNKPIYSPSPKKLQNENNSLKQENEKLQEEIEELQNTIDKLQIENKSPNKLQQ 2051

Query: 1312 KYADVINQIEILRSEIE 1328
            +   +  +IE L+ EIE
Sbjct: 2052 ENNSLKQEIENLKEEIE 2068



 Score =  155 bits (375), Expect = 1e-35
 Identities = 241/1193 (20%), Positives = 505/1193 (42%), Gaps = 75/1193 (6%)

Query: 233  KDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXX 292
            K E ++L + IE     I  L+ +NK    +  ++  E++ L QE+E             
Sbjct: 911  KQENEKLQEQIEELQNTIDKLQNSNK----SPNKLQQENNSLKQEIENLKEEIEQNNKSK 966

Query: 293  XXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATM 352
               +   ++   E   +  EK   +I    EL   +E L+  N  + + NK +      +
Sbjct: 967  SY-SPNKLQNENESLKQENEKLQEQIE---ELQNTVEKLQQEN-DLLKNNKSVSPSPKKL 1021

Query: 353  GTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEM 412
              E+  + + +K  SP   +    N + K ++   Q   E L    DK  N N+  K   
Sbjct: 1022 QQENDLLKN-NKSVSPSPKKLQNENNSLKQENEKLQEEIEELQNTIDKLQNSNKSPKK-- 1078

Query: 413  VIQSLNKDLVDKEYVI-SEKDTXXXXXXXXXXGKDTLIAQLQLEHQQH--MEGPSLIHVG 469
             +Q  NK +++    + +E +T            + L + ++   Q++  ++      V 
Sbjct: 1079 -LQQENKSMLNSPNKLQNEYETLQEENEKLQDEIEELQSTVEKLQQENDLLKNSKSKSVS 1137

Query: 470  TNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKV 529
             + + + +     +Q  ++L +EI  +  ++ IEKL++ + ++   + +    N+N    
Sbjct: 1138 PSPKRLQQENNSLKQENEKLQEEINQL--QNTIEKLQNNKSKLYSPSPK-KLQNENESLK 1194

Query: 530  KSNHKLK--LKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVD 587
            + N KL+  ++++Q+  D+  K S S +   +L +E + L Q+  +L+EE   LQ  +  
Sbjct: 1195 QENEKLQEQIEKLQQENDSKPKYSPSPR---KLQQENNSLKQENEKLQEEIDQLQNTIEK 1251

Query: 588  YDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADI 647
                      +     +++N  ET  +    L+ +  +L   +  LQQ+ +E+++     
Sbjct: 1252 LQQENNKSKSLLNTPNKLQNEYETLQEENDKLQDEIEELQSTVEKLQQENEELKNNKPIY 1311

Query: 648  S----QLQSDQVCSEIKSVHLEEQIDAL--------SASKKELALVIEN--LKLDKEQLY 693
            S    +LQ++    + ++  L+E+I+ L        +++K    L  EN  LK + E L 
Sbjct: 1312 SPSPKKLQNENNSLKQENEKLQEEIEELQNTIDKLQNSNKSPNKLQQENNSLKQEIENLK 1371

Query: 694  GTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGI 753
              I+     K    NKLQN   EN  L  + EK+  E+I EL   +   +Q     +   
Sbjct: 1372 EEIEQNNKSKSYSPNKLQN---ENESLKQENEKLQ-EEIEELQNTVEKLQQENDLLKNNK 1427

Query: 754  DAKIQERDLYIEN--IESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQK 811
                  + L  EN  ++ E  K +  I  L+ +I  +++   S ++   +  S L    K
Sbjct: 1428 SVSPSPKKLQNENNSLKQENEKLQEEIEELQNTIDKLQNSNKSPKKLQQENKSMLNSPNK 1487

Query: 812  AYSEY-TIQED---------ELVNRLAVLM-DHDRVVEKQLLEIEHENKELQKKNQILLE 860
              +EY T+QE+         EL + +  L  ++D +   +   +    K LQ++N  L +
Sbjct: 1488 LQNEYETLQEENEKLQDEIEELQSTVEKLQQENDLLKNSKSKSVSPSPKRLQQENNSLKQ 1547

Query: 861  ENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQ 920
            EN+ LQ  ++ +Q     L  + N++ L      K Q +   L+   +++  + + L  Q
Sbjct: 1548 ENEKLQEEINQLQNTIEKL--QNNKSKLYSPSPKKLQNENESLKQENEKLQEQIEKL--Q 1603

Query: 921  KKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEE 980
            ++ + +        +++      K  NEK ++ I+ +     +LQ+  N  ++L +N   
Sbjct: 1604 QENDSKPKYSPSPRKLQQENNSLKQENEKLQEEIDQLQNTIEKLQQENNKSKSL-LNTPN 1662

Query: 981  LNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYM 1040
              +   E + +   K Q +  +  +  I ++ + N  LK          +K+ N   S  
Sbjct: 1663 KLQNEYETLQEENDKLQDKIEEL-QSTIEKLQQENEELKNNKPIYSPSPKKLQNENNSLK 1721

Query: 1041 SMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVRE--QDDQIKELKET 1098
                  + ++ +    ++ ++ E +  +K   ++    +E++ L  E  Q+++ K     
Sbjct: 1722 QENEKLQEEIEELQNTIDKLQIENKSPNKLQQENNSLKQEIENLKEEIEQNNKSKSYSPK 1781

Query: 1099 KLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQER-SVL 1157
            KL  E N  K E   +   I+ + +  + +              K+Q+E E +Q     L
Sbjct: 1782 KLQQENNSLKQENEKLQEEIDELQNTVDKLQNENNLQSLQEENDKLQDEIEELQSTVEKL 1841

Query: 1158 QEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTV 1217
            Q+++ +L            +L+  N  L   +   QE+I +L++ +++L  EN +  + +
Sbjct: 1842 QQENEELKNNKPIYSPSPKKLQNENNSLKQENEKLQEEIEELQNTIDKLQIENKSP-NKL 1900

Query: 1218 AELRSSISSAVDQRGFEI-----AELWKQHLAQREADFQKTEHE-LRVQLSAFESKYEQL 1271
             +  +S+   ++    EI     ++ +     Q+E +  K E+E L+ ++   ++  ++L
Sbjct: 1901 QQENNSLKQEIENLKEEIEQNNKSKSYSPKKLQQENNSLKQENEKLQEEIDELQNTVDKL 1960

Query: 1272 LDSVQ-SSTQEETNKIVT-MEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIED 1329
             +     S QEE +K+   +E++ S   KLQ + E L+N +  Y+    +++   + ++ 
Sbjct: 1961 QNENNLQSLQEENDKLQDEIEELQSTVEKLQQENEELKNNKPIYSPSPKKLQNENNSLKQ 2020

Query: 1330 EKVAFXXXXXXXXXXXXXXXXDLRTEN--QSYKQMQEQSILNINEENAQLKKS 1380
            E                    + ++ N  Q      +Q I N+ EE  Q  KS
Sbjct: 2021 ENEKLQEEIEELQNTIDKLQIENKSPNKLQQENNSLKQEIENLKEEIEQNNKS 2073



 Score =  116 bits (280), Expect = 4e-24
 Identities = 181/1000 (18%), Positives = 438/1000 (43%), Gaps = 62/1000 (6%)

Query: 149  NTIKEKDNALSVLQVKMKIMETTILDLQ---EKINEKDQIIE-AKNKATTXXXXXXXXXX 204
            N+  +  N    LQ + + ++  I +LQ   EK+ +++ +++ +K+K+ +          
Sbjct: 1088 NSPNKLQNEYETLQEENEKLQDEIEELQSTVEKLQQENDLLKNSKSKSVSPSPKRLQQEN 1147

Query: 205  XXXXXXXEDTKQQMTKMQENFIAMEAE----WKDEKQRLLKDIESKDVRISSLEEANKLL 260
                   E  ++++ ++Q     ++      +    ++L  + ES       L+E  + L
Sbjct: 1148 NSLKQENEKLQEEINQLQNTIEKLQNNKSKLYSPSPKKLQNENESLKQENEKLQEQIEKL 1207

Query: 261  EAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIAN 320
            +    +   ++S   ++L+Q                 Q ++ + E+  +   K    +  
Sbjct: 1208 QQEN-DSKPKYSPSPRKLQQENNSLKQENEKLQEEIDQ-LQNTIEKLQQENNKSKSLLNT 1265

Query: 321  MTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTAS 380
              +L  + E L+  N +++   +EL++ +  +  E++ + +     SP   +    N + 
Sbjct: 1266 PNKLQNEYETLQEENDKLQDEIEELQSTVEKLQQENEELKNNKPIYSPSPKKLQNENNSL 1325

Query: 381  KMKSPWSQLSSETLNQDTDKKINKNEIA-KLEMVIQSLNKDLVDKEYVISEKDTXXXXXX 439
            K ++   Q   E L    DK  N N+   KL+    SL +++ + +  I + +       
Sbjct: 1326 KQENEKLQEEIEELQNTIDKLQNSNKSPNKLQQENNSLKQEIENLKEEIEQNNKSKSYSP 1385

Query: 440  XXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVN-V 498
                 ++  + Q   + Q+ +E   L +     +  N++ K  + +         + N +
Sbjct: 1386 NKLQNENESLKQENEKLQEEIE--ELQNTVEKLQQENDLLKNNKSVSPSPKKLQNENNSL 1443

Query: 499  KDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIV 558
            K   EKL+   E++    D++  +NK+  K++  +K  L    K  + +  + + N+++ 
Sbjct: 1444 KQENEKLQEEIEELQNTIDKLQNSNKSPKKLQQENKSMLNSPNKLQNEYETLQEENEKLQ 1503

Query: 559  RLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAE--TRLK-A 615
               EEL    +K+ +  +   N +   V     R+ + +   K  E E L E   +L+  
Sbjct: 1504 DEIEELQSTVEKLQQENDLLKNSKSKSVSPSPKRLQQENNSLKQ-ENEKLQEEINQLQNT 1562

Query: 616  ISLLESQKFDLVQ--------ELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQ 667
            I  L++ K  L          E   L+Q+ +++++++  + Q    +         L+++
Sbjct: 1563 IEKLQNNKSKLYSPSPKKLQNENESLKQENEKLQEQIEKLQQENDSKPKYSPSPRKLQQE 1622

Query: 668  IDALSASKKELALVIENLKLDKEQLY---GTIKDLENDKEDIMNKLQNYIQENMDLTDKL 724
             ++L    ++L   I+ L+   E+L       K L N    + N+ +   +EN  L DK+
Sbjct: 1623 NNSLKQENEKLQEEIDQLQNTIEKLQQENNKSKSLLNTPNKLQNEYETLQEENDKLQDKI 1682

Query: 725  EKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYI----ENIESELSKYKSRICR 780
            E++  +   E L + N E ++          K+Q  +  +    E ++ E+ + ++ I +
Sbjct: 1683 EEL--QSTIEKLQQENEELKNNKPIYSPSPKKLQNENNSLKQENEKLQEEIEELQNTIDK 1740

Query: 781  LE---ESIAVMEDRRYSLERKADQLGSYLQE--KQKAYSEYTIQEDELVNRLAVLMDHDR 835
            L+   +S   ++    SL+++ + L   +++  K K+YS   +Q++        L   + 
Sbjct: 1741 LQIENKSPNKLQQENNSLKQEIENLKEEIEQNNKSKSYSPKKLQQEN-----NSLKQENE 1795

Query: 836  VVEKQLLEIEHENKELQKKN--QILLEENQNLQISLSDMQQHYNALVEKANRTDLAESES 893
             +++++ E+++   +LQ +N  Q L EEN  LQ  + ++Q     L ++       +   
Sbjct: 1796 KLQEEIDELQNTVDKLQNENNLQSLQEENDKLQDEIEELQSTVEKLQQENEELKNNKPIY 1855

Query: 894  TKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNT-----QIESAIRDK-KVLN 947
            +    +L++  ++LK+   + Q  I + +  I+ L+IE  +     Q  ++++ + + L 
Sbjct: 1856 SPSPKKLQNENNSLKQENEKLQEEIEELQNTIDKLQIENKSPNKLQQENNSLKQEIENLK 1915

Query: 948  EKYEKNIEYVTQLEAQLQEYKNNIENLNMNV-EELNKMNLELIDKHVQKQQTQS-PDYTE 1005
            E+ E+N +  +    +LQ+  N+++  N  + EE++++    +DK   +   QS  +  +
Sbjct: 1916 EEIEQNNKSKSYSPKKLQQENNSLKQENEKLQEEIDELQ-NTVDKLQNENNLQSLQEEND 1974

Query: 1006 QYINEINKLNALLK--QKDEEIIALNQKINNAQVSYM----SMVSDYESKLAQFTTKLEN 1059
            +  +EI +L + ++  Q++ E +  N+ I +     +    + +     KL +   +L+N
Sbjct: 1975 KLQDEIEELQSTVEKLQQENEELKNNKPIYSPSPKKLQNENNSLKQENEKLQEEIEELQN 2034

Query: 1060 MEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETK 1099
              +++Q  +K     +Q N  L+  +    ++I++  ++K
Sbjct: 2035 TIDKLQIENKSPNKLQQENNSLKQEIENLKEEIEQNNKSK 2074



 Score =  103 bits (246), Expect = 5e-20
 Identities = 198/1007 (19%), Positives = 410/1007 (40%), Gaps = 106/1007 (10%)

Query: 639  EVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKD 698
            EV +   ++  LQ +    ++K   L++Q+  +    + +   IE     + Q   + +D
Sbjct: 33   EVGEYNQNVQDLQEENFSLKMKINALQQQLATVQEQYRTVTTRIEETTY-QYQSNDSSQD 91

Query: 699  LENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQ 758
              +          +      +  +KLE+ + E       K  ++E + +  Q  +D ++ 
Sbjct: 92   QNSTDPKTKGGSSSDFGSVAEWMEKLERATKENDDLKREKETYQELA-VTLQNQLDTQVS 150

Query: 759  ERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTI 818
              +  IE ++ E         +L+E I ++      L  K D          K   ++ I
Sbjct: 151  NFEFQIEKLQREKDDLSRLNVQLQEKIKLLSTSYTDLSAKFD----------KQNEDHEI 200

Query: 819  QEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNA 878
            +  +L++R    +       K  ++    NK+    NQI  E  +  +  L   ++ Y  
Sbjct: 201  EIAKLIDRQNERLKEIEESHKSNIQQIQTNKD-GLTNQIQQEFTKTKE-DLDKSRKEYKQ 258

Query: 879  LVEKANRTDLAESESTK----YQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNT 934
            L E   +   A+ E+TK       Q+  L++ L++     Q   V  KK I DLE   N 
Sbjct: 259  LEELQRK---AQEENTKTISLLNIQINQLQNQLEKAYSGKQADDVAVKKNIADLE-RSNA 314

Query: 935  QIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEEL--------NKMNL 986
            + +  I+    L+ K  +  E V+ LEA++ EY+  I+ LN + E+L        NK+++
Sbjct: 315  EKDVVIQS---LSTKVGRFEEKVSNLEAKISEYEKTIKQLNNSKEDLQKQINNFSNKIDI 371

Query: 987  ELIDKHVQ-------KQQTQSPDY-----TEQYINEINKL-------------NALLKQK 1021
            E  +K +        K+Q Q+ +       +++  E+  L             + L++  
Sbjct: 372  ERAEKQIYIENNNDLKEQIQNDEIKFQKERKEFQQELENLRIKFVQLSNNTEKDNLIQHL 431

Query: 1022 DEEIIALNQKINNAQVSYMSMVS-----DYESKLAQFTTKLENMEEEMQRVSKQLLDSKQ 1076
             EEI AL QK++       +  S      YES +    T++  ++ E Q + K + +   
Sbjct: 432  QEEINALRQKLSEYSKIVENSKSTPGKESYESTITNLRTQINMLKLENQEIKKDIENYDT 491

Query: 1077 HNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXX 1136
              ++ + + ++ DD   +LKE K  ++  +   E M     I+  +DD            
Sbjct: 492  MEKQNEEMKKQMDDLRSQLKENK-DYQSQL---ENM---KLIQEENDDLKERIGDMSNLS 544

Query: 1137 XXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQE----CYTKIIQLETLNTELTGHDVVN 1192
                 LK ++  +   E+ +L++Q   L  + +E     ++K+I    +  ++    + +
Sbjct: 545  DQILELK-KKLNDSENEKEILRKQIDNLCKDDEEEDVPTFSKVISDLKVENQILKKKISD 603

Query: 1193 QEQINQ----LKSKLEQ---LNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQ 1245
             EQI++    LK ++ +   +  END L   ++ L+++I   + +R  EI E     L +
Sbjct: 604  SEQISKENEDLKKQINEYIDIENENDELKDEISTLQNNIQK-ITERNEEI-EKQNDDLKK 661

Query: 1246 READFQKTEHELRVQLSAFESKYEQL-LDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEE 1304
               D     H L  ++    +   +L ++ ++    +E N ++  +  + +    + ++ 
Sbjct: 662  NNDDLHVKIHNLEQKVDNLTNLNNELTINQMKYEDIKEENDLLKNKSASPVSATPRTQQN 721

Query: 1305 HLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQE 1364
             ++ LQ +  ++  +IEIL   I  +K+                   L+ EN+    M +
Sbjct: 722  KIQQLQMRNDELKTEIEILHQTI--DKLTSARIKDNDSKTVDNEIDLLKKENERLNAMLD 779

Query: 1365 QSIL-------NINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIY 1417
             S +        I+E  +   K              + + +  K+ +  + L+ ++ ++ 
Sbjct: 780  DSSMQIIMLQQEIDENKSNSLKQENEKLQEQIEELQKHSPSPKKLQQENNSLKQENEKLQ 839

Query: 1418 QKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQ 1477
            ++  E   T+ +  +  EN  Q L E   +++D   E +S +  L+ +  E  N+     
Sbjct: 840  EEIEELQNTVDKLQN--ENNLQSLQEENDKLQDEIEELQSTVEKLQQENEELKNNKPIYS 897

Query: 1478 KESEIERVKLIEELNVKITESVSLNKQVAELNKA---LEEEVAKTNEMQTALENQEIEIV 1534
               +    KL  E N    E+  L +Q+ EL      L+      N++Q    + + EI 
Sbjct: 898  PSPK----KLQNENNSLKQENEKLQEQIEELQNTIDKLQNSNKSPNKLQQENNSLKQEIE 953

Query: 1535 TLNDEITNLQNMVRASSSKIQ---KHVSFASDTKQGRDEQLDNTMNK 1578
             L +EI         S +K+Q   + +   ++  Q + E+L NT+ K
Sbjct: 954  NLKEEIEQNNKSKSYSPNKLQNENESLKQENEKLQEQIEELQNTVEK 1000


>UniRef50_UPI0000DB6B83 Cluster: PREDICTED: similar to lava lamp
            CG6450-PC; n=1; Apis mellifera|Rep: PREDICTED: similar to
            lava lamp CG6450-PC - Apis mellifera
          Length = 3357

 Score =  193 bits (471), Expect = 3e-47
 Identities = 261/1195 (21%), Positives = 530/1195 (44%), Gaps = 129/1195 (10%)

Query: 445  KDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQ---EQLKQE---LNDEIKDVNV 498
            +D  + +   E Q  +   S+   G   E  N I +++   E+LKQ    L +E K    
Sbjct: 334  RDPTVDEFVAELQDKIVNISMHGNGAIVEKDNRIIELENLVEELKQSNKFLEEESKAELQ 393

Query: 499  KDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIV 558
            K + +     EE   ++ D  +  +K + + K+    KL + +  I    K+SD+N E+V
Sbjct: 394  KQVADLTLKNEEYSNKITDLENFVHK-LEEEKNEITAKLPE-EGIIKEDEKISDTNAELV 451

Query: 559  RLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLA-------ET 611
            RL         +VA LEEEKGNLQL LVD+D  +    D  ++++++E+         E 
Sbjct: 452  RL-------GNQVALLEEEKGNLQLSLVDFDELKASAGDWQERVVDLESKVSAQTKEIEM 504

Query: 612  RLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDAL 671
            +++AI+ LE+QK DL+QELH+ +Q+   +E + A+   L   +V +EIK V LEEQ++A+
Sbjct: 505  QIEAIATLENQKLDLLQELHMAKQEISSLEAENAESENL---RVTAEIKVVDLEEQLEAI 561

Query: 672  -------------SASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNY--IQE 716
                           +  EL   +E L  +  +LY  I   E          +++  IQE
Sbjct: 562  HRMQNESKLESSSEVNSAELIKQVETLTQENTELYNRISKFEEKGTSDTGSTESFEAIQE 621

Query: 717  NMDLTDKLEKMSAEKI--SELLAKI--NHEEQSKIQ--TQFGID-----AKIQERDLYIE 765
             +D TD +E+  +     +E   +I  N+E  +KI+  TQ   +      K++E+  YIE
Sbjct: 622  -LDKTDLVEEKGSSDTGSTESFERIPENNESMTKIELLTQENSELVIKLTKLEEQLEYIE 680

Query: 766  NIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVN 825
            +      K K     L + I ++      L  +  +L   ++ KQ   SE + ++ +   
Sbjct: 681  SKSDIDLKLKIDTLELHKEIEMLSINNTDLTIEPHKL--EIETKQSEESEISKRDVDFKT 738

Query: 826  RLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANR 885
            ++ +LM+   +++K++ E+ +  ++  +KNQ L  +  +L+  + ++ +    +V K + 
Sbjct: 739  QVNILMEEKDLLQKEVKELRNSLEQWHEKNQDL--QINDLRTKIEELLRENEEVVTKMSE 796

Query: 886  TDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEI-EDLEIEFNTQIESAIRDKK 944
                ++ + K +     L   L ++  E Q   +Q+KK++ E ++I      +  ++  +
Sbjct: 797  ---LKTSNQKLEENTLKLTEKLDKLNLEKQN--IQEKKQLDEQIDIPLEKSDQELLKTPQ 851

Query: 945  VLNEKYEKNIE--YVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPD 1002
             L+E   +  E   V  LE ++++ KN I      +EE+ K+ L   +K ++++  Q  D
Sbjct: 852  -LDEPLSQQTESTIVASLEQEIEKCKNLIAEQTGLIEEM-KIKLVNKEKELEEKSQQIVD 909

Query: 1003 ------YTEQYINEINKLNALLKQ---KDEEIIALNQKINNAQVSY-------MSMVSDY 1046
                    E   NE+ ++ + +++   K  E+    +K+ +  V++       +S++S+ 
Sbjct: 910  CERSGKKVETLENELREMFSTIEEWRYKCNEMEEKMEKLEDTTVTFESKLERQISIISEK 969

Query: 1047 ESKLAQFTTKLENMEEEMQRVSKQL------LDSKQHN-EELQILVREQDDQIKELKETK 1099
            E+++ +    +E  ++E+Q    +L      +DS Q      ++L++E+D  I  +    
Sbjct: 970  ENEIIRLKETIEEKDQELQAKYTELQNKMITIDSLQDEFNNCKMLIQEKDTSITSMTNEV 1029

Query: 1100 LTFEMNIPKTEGMIIS--STIEPMSD---------DANNVDXXXXXXXXXXXXLK----- 1143
                  +   E  I S    I  +SD         D N++             L+     
Sbjct: 1030 ANLNNLVKSKEEEIYSLRKNITELSDKLEQSIPVKDYNDLMEKLKDKNMIVDELECRINA 1089

Query: 1144 -VQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSK 1202
              +E     ++   L +Q+  +  +L E   +++ L T    L    V  +++  +++ +
Sbjct: 1090 TTKENSNLSEKVKNLSQQNNDIQNQLTEKQRELVDLITTKDHLEAEIVETKDEKGEVERR 1149

Query: 1203 LEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLS 1262
            + +L T  DN    V +L++ + S   Q    + +L  +H    +   Q+ E  +  +L+
Sbjct: 1150 VWELQTIIDNNTKFVNDLQTELRSNYKQ----MEQLKSKHAEDTQLQNQRLETVIE-ELT 1204

Query: 1263 AFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEI 1322
            A   + E L + ++   +    + VT E   +L++K+ D E+ L++ +EK    + +++ 
Sbjct: 1205 AKMRECEILKEELEQK-ERLIGRNVTEEAKVALESKVADLEKRLKDSEEKVQLQLEKMKK 1263

Query: 1323 LRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQ---------EQSILNINEE 1373
            + + ++ +                    +   +    KQ+Q         +  I ++ E+
Sbjct: 1264 IAANLKKKTAVCQELETRVAELEEKWTTEKDEKEAKNKQIQDVEITIREKDNRIADLEEK 1323

Query: 1374 NAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQ---KTHEYTITLTQR 1430
             AQ +  S              ++ + K+  LT Q+   + EI +        T  LT  
Sbjct: 1324 LAQSRNESSQASKNIERLTTDSSNLKEKMASLTQQIAEMEEEIVKLRVDLESSTTDLTLE 1383

Query: 1431 NDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEE 1490
             +  + V  +   Y +++      ++ EL  ++ K  E +   + M+ E  +E + LI +
Sbjct: 1384 KESRQLVSSEYESYRRQVVQENERRQLELDEMKEKARELSVRMQVMEAE-YVEHLTLIND 1442

Query: 1491 LNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALEN-QEIEIVTLNDEITNLQ 1544
            L  K    + L+KQ A +N+ LE    ++ E +  LE  ++  +V    E T  Q
Sbjct: 1443 L--KAENGLLLSKQ-AHINEKLETVEKESEERRLLLEQLEKAAVVNTRAEATQTQ 1494



 Score =  164 bits (399), Expect = 2e-38
 Identities = 261/1253 (20%), Positives = 553/1253 (44%), Gaps = 130/1253 (10%)

Query: 168  METTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIA 227
            +ETTI+DLQE + EKD +IE+K KA T                 EDTK +M  MQE+F+ 
Sbjct: 160  IETTIMDLQENLKEKDSVIESKTKAVTLMSADLSKRGKTTLDTLEDTKDEMRTMQEHFVL 219

Query: 228  MEAEWKDEKQRLLKDIESKDVRISSLEEA----NKLLEAARFE--ISLEHSKLAQELEQX 281
            +E   K++ + LL  ++ +D +I  LE++     K +   +     S++ S+   +    
Sbjct: 220  LETSLKNKNENLLMQLQERDDKIVELEDSVDRFRKQINEQKLSETASVDFSRSTMDTLVE 279

Query: 282  XXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHL--NCQIR 339
                         L + S++   +   E  +   L++A   E   K+E    +  +  + 
Sbjct: 280  TKEAMKSMQENFVLMESSLKAKNDNLLEQLKDYELKLAEANERVFKLESGIGIVRDPTVD 339

Query: 340  QTNKELENKLATMGTESK-AVSSPSKKGSPLIS-----RKSGRNTASKMKSP-WSQLSSE 392
            +   EL++K+  +      A+     +   L +     ++S +    + K+    Q++  
Sbjct: 340  EFVAELQDKIVNISMHGNGAIVEKDNRIIELENLVEELKQSNKFLEEESKAELQKQVADL 399

Query: 393  TL-NQDTDKKIN--KNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLI 449
            TL N++   KI   +N + KLE     +   L ++  +  ++            G    +
Sbjct: 400  TLKNEEYSNKITDLENFVHKLEEEKNEITAKLPEEGIIKEDEKISDTNAELVRLGNQVAL 459

Query: 450  AQLQLEHQQ--HMEGPSL-IHVGTNTEDVNEI-AKVQEQLKQELNDEIKDV----NVK-D 500
             + +  + Q   ++   L    G   E V ++ +KV  Q K E+  +I+ +    N K D
Sbjct: 460  LEEEKGNLQLSLVDFDELKASAGDWQERVVDLESKVSAQTK-EIEMQIEAIATLENQKLD 518

Query: 501  LIEKLKSAEEQITQLNDEIDAANKNM-----IKV----KSNHKLKLKQMQKTIDNFSKVS 551
            L+++L  A+++I+ L  E +A ++N+     IKV    +    +   Q +  +++ S+V+
Sbjct: 519  LLQELHMAKQEISSLEAE-NAESENLRVTAEIKVVDLEEQLEAIHRMQNESKLESSSEVN 577

Query: 552  DSN--KEIVRLTEELHHLSQKVAELEE----EKGNLQLH--LVDYDSGRMIE---SDVYK 600
             +   K++  LT+E   L  ++++ EE    + G+ +    + + D   ++E   S    
Sbjct: 578  SAELIKQVETLTQENTELYNRISKFEEKGTSDTGSTESFEAIQELDKTDLVEEKGSSDTG 637

Query: 601  KMIEMENLAETR--LKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSE 658
                 E + E    +  I LL  +  +LV +L  L+++ + +E K +DI       +  +
Sbjct: 638  STESFERIPENNESMTKIELLTQENSELVIKLTKLEEQLEYIESK-SDI------DLKLK 690

Query: 659  IKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQ-NYIQEN 717
            I ++ L ++I+ LS +  +L +    L+++ +Q     ++ E  K D+  K Q N + E 
Sbjct: 691  IDTLELHKEIEMLSINNTDLTIEPHKLEIETKQ----SEESEISKRDVDFKTQVNILMEE 746

Query: 718  MDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSR 777
             DL  K  K     + +      HE+   +Q    +  KI+E     E + +++S+ K+ 
Sbjct: 747  KDLLQKEVKELRNSLEQW-----HEKNQDLQIN-DLRTKIEELLRENEEVVTKMSELKTS 800

Query: 778  ICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVV 837
              +LEE+   + ++   L  +       +QEK++   +  I  ++    L      D  +
Sbjct: 801  NQKLEENTLKLTEKLDKLNLEKQN----IQEKKQLDEQIDIPLEKSDQELLKTPQLDEPL 856

Query: 838  EKQLLE--IEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTK 895
             +Q     +    +E++K   ++ E+   ++     +      L EK+ +    E    K
Sbjct: 857  SQQTESTIVASLEQEIEKCKNLIAEQTGLIEEMKIKLVNKEKELEEKSQQIVDCERSGKK 916

Query: 896  YQT---QLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIE---SAIRDKKVLNEK 949
             +T   +LR++ S ++   ++   +  +K +++ED  + F +++E   S I +K+    +
Sbjct: 917  VETLENELREMFSTIEEWRYKCNEM-EEKMEKLEDTTVTFESKLERQISIISEKENEIIR 975

Query: 950  YEKNIEYVTQ-LEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYI 1008
             ++ IE   Q L+A+  E +N +  ++   +E N  N +++   +Q++ T     T    
Sbjct: 976  LKETIEEKDQELQAKYTELQNKMITIDSLQDEFN--NCKML---IQEKDTSITSMT---- 1026

Query: 1009 NEINKLNALLKQKDEEIIALNQKIN--NAQVSYMSMVSDYESKLAQFTTK---LENME-- 1061
            NE+  LN L+K K+EEI +L + I   + ++     V DY   + +   K   ++ +E  
Sbjct: 1027 NEVANLNNLVKSKEEEIYSLRKNITELSDKLEQSIPVKDYNDLMEKLKDKNMIVDELECR 1086

Query: 1062 -----EEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKT---EGMI 1113
                 +E   +S+++ +  Q N ++Q  + E+  ++ +L  TK   E  I +T   +G +
Sbjct: 1087 INATTKENSNLSEKVKNLSQQNNDIQNQLTEKQRELVDLITTKDHLEAEIVETKDEKGEV 1146

Query: 1114 ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYT 1173
                 E  +   NN               K Q E+   +     Q Q+ +L T ++E   
Sbjct: 1147 ERRVWELQTIIDNNTKFVNDLQTELRSNYK-QMEQLKSKHAEDTQLQNQRLETVIEELTA 1205

Query: 1174 KIIQLETLNTE------LTGHDVVNQEQI----------NQLKSKLEQLNTENDNLLSTV 1217
            K+ + E L  E      L G +V  + ++           +LK   E++  + + +    
Sbjct: 1206 KMRECEILKEELEQKERLIGRNVTEEAKVALESKVADLEKRLKDSEEKVQLQLEKMKKIA 1265

Query: 1218 AEL--RSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSV 1275
            A L  ++++   ++ R  E+ E W     ++EA   K   ++ + +   +++   L + +
Sbjct: 1266 ANLKKKTAVCQELETRVAELEEKWTTEKDEKEAK-NKQIQDVEITIREKDNRIADLEEKL 1324

Query: 1276 QSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIE 1328
              S  E +     +E++T+  + L++K   + +L ++ A++  +I  LR ++E
Sbjct: 1325 AQSRNESSQASKNIERLTTDSSNLKEK---MASLTQQIAEMEEEIVKLRVDLE 1374



 Score =  144 bits (349), Expect = 2e-32
 Identities = 279/1430 (19%), Positives = 596/1430 (41%), Gaps = 119/1430 (8%)

Query: 212  EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271
            E      TK  E  I   A  +++K  LL+++      ISSLE  N   E  R    ++ 
Sbjct: 492  ESKVSAQTKEIEMQIEAIATLENQKLDLLQELHMAKQEISSLEAENAESENLRVTAEIKV 551

Query: 272  SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELL 331
              L ++LE               + +   E   E  +E+         N  EL K++E L
Sbjct: 552  VDLEEQLE--------------AIHRMQNESKLESSSEV---------NSAELIKQVETL 588

Query: 332  EHLNCQIRQTNKELENK--LATMGTES-KAVSSPSKKGSPLISRKSGRNTASKMKSPWSQ 388
               N ++     + E K    T  TES +A+    K  + L+  K   +T S        
Sbjct: 589  TQENTELYNRISKFEEKGTSDTGSTESFEAIQELDK--TDLVEEKGSSDTGSTESFERIP 646

Query: 389  LSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTL 448
             ++E++   T  ++   E ++L + +  L + L   EY+ S+ D                
Sbjct: 647  ENNESM---TKIELLTQENSELVIKLTKLEEQL---EYIESKSDIDLKLKIDTLE-LHKE 699

Query: 449  IAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEK-LKS 507
            I  L + +      P  + + T   + +EI+K     K ++N  +++   KDL++K +K 
Sbjct: 700  IEMLSINNTDLTIEPHKLEIETKQSEESEISKRDVDFKTQVNILMEE---KDLLQKEVKE 756

Query: 508  AEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEI----VRLTEE 563
                + Q +++      N ++ K      L++ ++ +   S++  SN+++    ++LTE+
Sbjct: 757  LRNSLEQWHEKNQDLQINDLRTKIEE--LLRENEEVVTKMSELKTSNQKLEENTLKLTEK 814

Query: 564  LHHLSQKVAELEEEKGNLQL-HLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQ 622
            L  L+ +   ++E+K   QL   +D    +  +  +    ++     +T    ++ LE Q
Sbjct: 815  LDKLNLEKQNIQEKK---QLDEQIDIPLEKSDQELLKTPQLDEPLSQQTESTIVASLE-Q 870

Query: 623  KFDLVQELHILQQK--YDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELAL 680
            + +  + L I +Q    +E++ KL +  +   ++    +      ++++ L    +E+  
Sbjct: 871  EIEKCKNL-IAEQTGLIEEMKIKLVNKEKELEEKSQQIVDCERSGKKVETLENELREMFS 929

Query: 681  VIENLKLDKEQLYGTIKDLENDKEDIMNKLQ---NYIQENMDLTDKLEKMSAEKISELLA 737
             IE  +    ++   ++ LE+      +KL+   + I E  +   +L++   EK  EL A
Sbjct: 930  TIEEWRYKCNEMEEKMEKLEDTTVTFESKLERQISIISEKENEIIRLKETIEEKDQELQA 989

Query: 738  KINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLER 797
            K   E Q+K+ T   +  +     + I+  ++ ++   + +  L   +   E+  YSL +
Sbjct: 990  KYT-ELQNKMITIDSLQDEFNNCKMLIQEKDTSITSMTNEVANLNNLVKSKEEEIYSLRK 1048

Query: 798  KADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQI 857
               +L   L E+     +Y    ++L ++  ++ +    +E ++     EN  L +K + 
Sbjct: 1049 NITELSDKL-EQSIPVKDYNDLMEKLKDKNMIVDE----LECRINATTKENSNLSEKVKN 1103

Query: 858  LLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTL 917
            L ++N ++Q  L++ Q+    LV+     D  E+E      + +D +  ++R   E QT+
Sbjct: 1104 LSQQNNDIQNQLTEKQRE---LVDLITTKDHLEAEI----VETKDEKGEVERRVWELQTI 1156

Query: 918  IVQKKKEIEDLEIEFNT------QIESA-IRDKKVLNEKYEKNIEYVTQLEAQLQEYKNN 970
            I    K + DL+ E  +      Q++S    D ++ N++ E  IE +T    + +  K  
Sbjct: 1157 IDNNTKFVNDLQTELRSNYKQMEQLKSKHAEDTQLQNQRLETVIEELTAKMRECEILKEE 1216

Query: 971  IEN----LNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEII 1026
            +E     +  NV E  K+ LE     ++K+   S +  +  + ++ K+ A LK+K     
Sbjct: 1217 LEQKERLIGRNVTEEAKVALESKVADLEKRLKDSEEKVQLQLEKMKKIAANLKKKTAVCQ 1276

Query: 1027 ALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVS---KQLLDSKQHNEELQI 1083
             L  ++   +  + +   + E+K  Q       + E+  R++   ++L  S+  + +   
Sbjct: 1277 ELETRVAELEEKWTTEKDEKEAKNKQIQDVEITIREKDNRIADLEEKLAQSRNESSQASK 1336

Query: 1084 LVREQDDQIKELKETKLTFEMNIPKTEGMIISSTI--EPMSDDANNVDXXXXXXXXXXXX 1141
             +         LKE   +    I + E  I+   +  E  + D                 
Sbjct: 1337 NIERLTTDSSNLKEKMASLTQQIAEMEEEIVKLRVDLESSTTDLTLEKESRQLVSSEYES 1396

Query: 1142 LK---VQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHD---VVNQEQ 1195
             +   VQE E    E   ++E++ +L+  +Q    + ++  TL  +L   +   +  Q  
Sbjct: 1397 YRRQVVQENERRQLELDEMKEKARELSVRMQVMEAEYVEHLTLINDLKAENGLLLSKQAH 1456

Query: 1196 INQLKSKLEQLNTENDNLLSTV--AELRSSISSAVDQRGFEIAELWKQHLAQREADFQKT 1253
            IN+    +E+ + E   LL  +  A + ++ + A   +G E  E+  +   +     Q  
Sbjct: 1457 INEKLETVEKESEERRLLLEQLEKAAVVNTRAEATQTQGEE--EMANEDEGKTSGALQHC 1514

Query: 1254 EH--ELRVQLSAFESKYEQLLDSVQSSTQEETNKI---VTMEQVTSLQNKLQDKEEHLRN 1308
             H  + +  + A E+K ++    +++   E  N I   V M +     + +       R 
Sbjct: 1515 THCEQCQTLVQALEAKLQEREAEIENLDNELANSIGNFVQMRESLRFNDLMNQTGMRNRT 1574

Query: 1309 LQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSIL 1368
            L++ Y D++ Q   L S  E+ KV+                  LR  N ++ Q +  ++ 
Sbjct: 1575 LEDPYNDLLFQYNSLASSHEEVKVSL-EKASRENEELRGTVDQLRVTNDTF-QERITTLE 1632

Query: 1369 NINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQL-----ELKDSEIYQKTHEY 1423
            N++  N+ L K               +   + +  EL  +L      LK  E  ++  E 
Sbjct: 1633 NVDALNSDLVKKWEERERELLNARQELEIVQRRGDELERRLNAQAESLKSVEARREAAEK 1692

Query: 1424 TITLTQRN--DEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESE 1481
            ++  T+ +   E E++R      E++++DL    E+EL   R +   +A   +   +  +
Sbjct: 1693 SLRDTKESLEREIESLRMDKDSSERKMKDL----ETELDAWRSRESFDAPPRDNAPQLFD 1748

Query: 1482 IERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEIT 1541
              R+      +   +E ++  ++V  L   LEE  A+ + +   +   +    TL++E  
Sbjct: 1749 ASRI-FGSAPSPLDSEPLADREEVKRLRSLLEEREAQCSNLTQEVYQLQ---GTLSEERR 1804

Query: 1542 NLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDL 1591
             ++ + +AS  ++  ++  A  +   +++Q++ +++ EL ++  R E +L
Sbjct: 1805 LIEGL-KASQKELSTNLERAERSVAEKEKQVE-SLDAELRNSTIRMEDEL 1852



 Score =  141 bits (342), Expect = 1e-31
 Identities = 226/1131 (19%), Positives = 505/1131 (44%), Gaps = 108/1131 (9%)

Query: 473  EDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSN 532
            + +NE  K+ E    + +    D  V+   E +KS +E    +   + A N N+++   +
Sbjct: 254  KQINE-QKLSETASVDFSRSTMDTLVETK-EAMKSMQENFVLMESSLKAKNDNLLEQLKD 311

Query: 533  HKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGR 592
            ++LKL +  + +       +S   IVR       + + VAEL+++  N+ +H     +G 
Sbjct: 312  YELKLAEANERVFKL----ESGIGIVRDPT----VDEFVAELQDKIVNISMH----GNGA 359

Query: 593  MIESDVYKKMIEMENLAETRLKAISLLESQ-KFDLVQELHILQQKYDEVEDKLADISQLQ 651
            ++E D   ++IE+ENL E   ++   LE + K +L +++  L  K +E  +K+ D+    
Sbjct: 360  IVEKD--NRIIELENLVEELKQSNKFLEEESKAELQKQVADLTLKNEEYSNKITDLENF- 416

Query: 652  SDQVCSEIKSVH-LEEQIDALSASKKELALVIENLKL-----DKEQLYGTIKDLENDKED 705
                      VH LEE+ + ++A   E  ++ E+ K+     +  +L   +  LE +K +
Sbjct: 417  ----------VHKLEEEKNEITAKLPEEGIIKEDEKISDTNAELVRLGNQVALLEEEKGN 466

Query: 706  IMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIE 765
            +   L ++ +      D       E++ +L +K++  +  +I+ Q    A ++ + L   
Sbjct: 467  LQLSLVDFDELKASAGD-----WQERVVDLESKVS-AQTKEIEMQIEAIATLENQKL--- 517

Query: 766  NIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVN 825
            ++  EL   K  I  LE   A  E+ R + E K   L   L+   +  +E  ++    VN
Sbjct: 518  DLLQELHMAKQEISSLEAENAESENLRVTAEIKVVDLEEQLEAIHRMQNESKLESSSEVN 577

Query: 826  RLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANR 885
              A L+     + ++  E+ +   + ++K        ++ + ++ ++ +    LVE+   
Sbjct: 578  S-AELIKQVETLTQENTELYNRISKFEEKGTSDTGSTESFE-AIQELDK--TDLVEEKGS 633

Query: 886  TDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLE-IEFNTQIESAIR-DK 943
            +D   +ES +   +  +  + ++ +T E+  L+++  K  E LE IE  + I+  ++ D 
Sbjct: 634  SDTGSTESFERIPENNESMTKIELLTQENSELVIKLTKLEEQLEYIESKSDIDLKLKIDT 693

Query: 944  KVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNK--------MNLELIDKH-VQ 994
              L+++ E  +  +   +  ++ +K  IE       E++K        +N+ + +K  +Q
Sbjct: 694  LELHKEIE--MLSINNTDLTIEPHKLEIETKQSEESEISKRDVDFKTQVNILMEEKDLLQ 751

Query: 995  KQQTQSPDYTEQYINEINKLNAL-LKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQF 1053
            K+  +  +  EQ+  +   L    L+ K EE++  N+++    V+ MS +     KL + 
Sbjct: 752  KEVKELRNSLEQWHEKNQDLQINDLRTKIEELLRENEEV----VTKMSELKTSNQKLEEN 807

Query: 1054 TTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMI 1113
            T KL    +++    + + + KQ +E++ I + + D   +EL +T    E    +TE  I
Sbjct: 808  TLKLTEKLDKLNLEKQNIQEKKQLDEQIDIPLEKSD---QELLKTPQLDEPLSQQTESTI 864

Query: 1114 ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYT 1173
            ++S +E   +   N+             +K+  +E+ ++E+S           ++ +C  
Sbjct: 865  VAS-LEQEIEKCKNL-IAEQTGLIEEMKIKLVNKEKELEEKS----------QQIVDCER 912

Query: 1174 KIIQLETLNTELTGHDVVNQE---QINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQ 1230
               ++ETL  EL       +E   + N+++ K+E+L    D  ++  ++L   I S + +
Sbjct: 913  SGKKVETLENELREMFSTIEEWRYKCNEMEEKMEKL---EDTTVTFESKLERQI-SIISE 968

Query: 1231 RGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTM- 1289
            +  EI  L K+ + +++ + Q    EL+ ++   +S  ++  ++ +   QE+   I +M 
Sbjct: 969  KENEIIRL-KETIEEKDQELQAKYTELQNKMITIDSLQDE-FNNCKMLIQEKDTSITSMT 1026

Query: 1290 EQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXX 1349
             +V +L N ++ KEE + +L++   ++ +++E      +   +                 
Sbjct: 1027 NEVANLNNLVKSKEEEIYSLRKNITELSDKLEQSIPVKDYNDLMEKLKDKNMIVDELECR 1086

Query: 1350 XDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQL 1409
             +  T+  S   + E+ + N++++N  ++                 +  EA+++E   + 
Sbjct: 1087 INATTKENS--NLSEK-VKNLSQQNNDIQNQLTEKQRELVDLITTKDHLEAEIVETKDE- 1142

Query: 1410 ELKDSEIYQKTHEYTITLTQRNDEFEN-VRQQLVEYEKRIEDLTYEKESELAILRLKMHE 1468
                 E+ ++  E   T+   N +F N ++ +L    K++E L  +   +  +   ++  
Sbjct: 1143 ---KGEVERRVWELQ-TIIDNNTKFVNDLQTELRSNYKQMEQLKSKHAEDTQLQNQRLET 1198

Query: 1469 NANHYETMQKESEI--ERVKLIEEL---NVKITESVSLNKQVAELNKALEEEVAKTNEMQ 1523
                     +E EI  E ++  E L   NV     V+L  +VA+L K L++   K   +Q
Sbjct: 1199 VIEELTAKMRECEILKEELEQKERLIGRNVTEEAKVALESKVADLEKRLKDSEEK---VQ 1255

Query: 1524 TALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDN 1574
              LE  +     L  +    Q +     +++++  +   D K+ +++Q+ +
Sbjct: 1256 LQLEKMKKIAANLKKKTAVCQEL-ETRVAELEEKWTTEKDEKEAKNKQIQD 1305



 Score =  135 bits (327), Expect = 8e-30
 Identities = 294/1479 (19%), Positives = 602/1479 (40%), Gaps = 151/1479 (10%)

Query: 212  EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISS-LEEANKLLEAARFEISLE 270
            E+ + Q + + +    ++    +E+ RL++ +++    +S+ LE A +    A  E  +E
Sbjct: 1779 EEREAQCSNLTQEVYQLQGTLSEER-RLIEGLKASQKELSTNLERAER--SVAEKEKQVE 1835

Query: 271  HSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIEL 330
               L  EL                   + ++        ++E  +LE A + E  ++  L
Sbjct: 1836 --SLDAELRNSTIRMEDELRESLSAKDEQLKELNARLDSVKE--TLEEA-LVERDRQHSL 1890

Query: 331  LEHLNCQIRQTNKELENKL---ATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWS 387
            L     QI     EL N     A    E + +S   ++    +       +  ++K   +
Sbjct: 1891 LRSYESQINDLEMELRNSTDLDALQDLEKRVLSLTKERDLLQLQVNDLTRSMEELKDSIN 1950

Query: 388  Q-LSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKD 446
            +  +SE      ++   +  IA L   ++   +   DK  V  +  T           ++
Sbjct: 1951 RGRNSEMEKVGRERDEARETIASLSRALEEARERQSDKATVTDDTSTKESLERRASKIEE 2010

Query: 447  TLIAQLQLEHQQHMEGPSLIHVGTNTEDV---NEIAKVQEQLKQELNDEIKDVNVKDLIE 503
              ++ L +   + +     I  G NTED    +E A     L      +++   V DL +
Sbjct: 2011 RSVS-LDVGEMEKINVDEEIW-GWNTEDAQLDSEQAMASTILIPSTEIQLR-AKVDDLQD 2067

Query: 504  KLKSAEEQITQLNDEIDAA---NKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRL 560
            ++K  E +  ++ +E  AA   N  M+K    +K + + +Q+ +    K+  +  +   L
Sbjct: 2068 QVKDLERERARMGEENKAAQLRNAKMLKKLKEYKAQAESLQQQL----KIQKTAADFYGL 2123

Query: 561  TEELHHLSQKVAELEEEKGNLQLHLVDYDSGR---MIESDVYKKMIEMENLAETRLKAIS 617
               +        EL+ + G L+ +L +    R   + E +   K +++   A  R   + 
Sbjct: 2124 DSAIEE------ELKSQIGKLEKNLNEVKEERRNTVAEKEALMKRLDVVVSANERY--ME 2175

Query: 618  LLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKE 677
            + E Q  D+     +L+ +  E+ DK+  + +   D   S  + V  +   +   A++++
Sbjct: 2176 MKERQDMDM----EVLRIRNKELSDKVEILDKRLQD---STFRLVEDDTSSEQKVATQEQ 2228

Query: 678  LALVIENLKLDKE-QLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELL 736
             +   E   L KE  L    K  + + +D+ ++++    EN  L   LE+    K+S L 
Sbjct: 2229 ASSSREKRSLPKEADLESLSKRYKEEMDDLKDEMEALATENEQLQHFLEEQKI-KLSALE 2287

Query: 737  AKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLE 796
            +K + EE   IQ    ++ KI E    +     E    + +    E+S+    D+  ++ 
Sbjct: 2288 SKRSAEEDESIQIVDDLNGKISELQAVLSKSREEYDLLRKQY---EQSLMDANDQVTAMR 2344

Query: 797  RKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQ 856
            + AD L      K++A+      E E+V+           + +QL   E    EL+K  +
Sbjct: 2345 QNADYL------KEEAFERTAKLEMEIVD-----------LRQQLEASELNVTELRKGLE 2387

Query: 857  ILLEENQNLQISLSDMQQHYNALVEKANRTDLAESE--STKYQTQLRDLESNLKRITHEH 914
              L E  +++  L+D+       V   N + L  ++  +T+ Q ++ DL   L++   EH
Sbjct: 2388 DALREKSSVEERLTDLTASTEKQVSSLNASMLEVTDLLNTRIQ-EVADLRQELQKQYVEH 2446

Query: 915  QTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKY-EKNIEYVTQLEAQLQEYKNNIEN 973
            +    + K  ++    E N +++   ++ + L   + E+  E+V +    ++     +  
Sbjct: 2447 E----EAKTRLQSTVKESNRELDEKRQEMEDLRRSFAEREKEFVER--QSVETVSALVSQ 2500

Query: 974  LNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINE--INKLNAL--LKQKDEEIIALN 1029
                + + + + +E  DKHV +   +     E   NE  + K N +  L  + +E+  L 
Sbjct: 2501 ATQELMQRHAIEIEERDKHV-RNLNERLSALEATANECLLEKRNNVVQLDARIQELELLR 2559

Query: 1030 QKINNAQVSYMSMVSDY---ESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVR 1086
            + +   + S  S+   +   E +LAQ   +L   EE ++++S +     +  EEL+  + 
Sbjct: 2560 RDLMEKESSLASVREGFASMEKQLAQRELELSEREETIRKLSLENQRCVETVEELRKRLN 2619

Query: 1087 EQDDQIKELKETKL---TFEMNIPKTEGM------IISSTIEPMSDDANNVDXXXXXXXX 1137
            E       + E  L   T E  +     +      I+   +E  ++    ++        
Sbjct: 2620 ESATISANVNEYTLRVQTLEREVENMRSLLDEKEAILRKNVEEATEYREIIEKSRIELSE 2679

Query: 1138 XXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQL-ETLNTELTGHDVVN---- 1192
                ++VQ+ E+   E    +E+   LN+EL+     + +  + LN +++  D  N    
Sbjct: 2680 LR--MEVQKVEDLKNELLEKEERVNSLNSELEATRKALEETRQNLNEKMSLLDHSNRLLN 2737

Query: 1193 --QEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQ-H-LAQREA 1248
              Q +I++L S L+Q    + N++  +   R        Q   +  ++ ++ H L   +A
Sbjct: 2738 ERQMEIDRLSS-LQQDRRSSANMIDGLPVFRMGNGEQNLQHTIDNMQMQQRIHCLYNEKA 2796

Query: 1249 DFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNK----------IVTMEQVTSLQNK 1298
            + + +   +  +    E +   L   +++ +QE  +K          I   EQ+  LQN+
Sbjct: 2797 ELESSLLVINARAEEKEKQIHALEQRIETQSQEFVSKEELHSRDRRSIQEQEQIVRLQNE 2856

Query: 1299 LQDKEEHLRNLQEKYADVINQIEILRS-----------EIEDEKVAFXXXXXXXXXXXXX 1347
            L  KE+ +  L+   A+  +Q+ +  S           E+     A              
Sbjct: 2857 LYAKEQEINELKYIVAEKESQLSVQASMEPQSDEFELREMVQRLTAELYGKEEEVKHTKL 2916

Query: 1348 XXXDLRTEN---QSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLE 1404
               +L+ E    Q +++  EQ+   + + NA+ ++              R+ + E ++ E
Sbjct: 2917 TIVELQREVSRLQEFERFSEQTREAVQKLNAEKEQ---IRLEGEEFLERRLKEKEMEIDE 2973

Query: 1405 LTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEY---EKRIEDLTYEKESELAI 1461
            +   L +++ +I  +       L+  N + E+++ QL E    E+R +D    +E +L  
Sbjct: 2974 IKRNLAMENQKILDE-------LSFNNRDIESLKSQLTELSTTEQRTKDELRRREEDL-- 3024

Query: 1462 LRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNE 1521
            LR+    N++  E  ++ +E+   K  E  N+KI  S   + ++ EL    EE   +  E
Sbjct: 3025 LRV----NSDLAEKKRRLAELSITKDAELHNLKIQISEK-DARIEELVSLYEEGEKRFTE 3079

Query: 1522 MQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELL 1581
            ++  L  +EIEI +L   + +     +   + ++K VS    +    +   + + +K   
Sbjct: 3080 LKNTLSAREIEINSLKTLLEDKVKEYQLIQNVLKKDVSVLDTSTSTTNPNTETSDDKSKT 3139

Query: 1582 DAVPRAELDLAMYMLHQRDVRCXXXXXXXXXXXXXRDTL 1620
                  ELDLA+YMLHQRDVRC             RDTL
Sbjct: 3140 ST--SQELDLALYMLHQRDVRCEELTHELMQLLEERDTL 3176



 Score =  112 bits (270), Expect = 7e-23
 Identities = 290/1524 (19%), Positives = 611/1524 (40%), Gaps = 151/1524 (9%)

Query: 143  DVTHLSNTIKEKDNAL-----SVLQVKMKIMETTIL----DLQEKINEKDQII---EAKN 190
            +V +L+N +K K+  +     ++ ++  K+ ++  +    DL EK+ +K+ I+   E + 
Sbjct: 1028 EVANLNNLVKSKEEEIYSLRKNITELSDKLEQSIPVKDYNDLMEKLKDKNMIVDELECRI 1087

Query: 191  KATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAM-------EAE---WKDEKQRLL 240
             ATT                  D + Q+T+ Q   + +       EAE    KDEK  + 
Sbjct: 1088 NATTKENSNLSEKVKNLSQQNNDIQNQLTEKQRELVDLITTKDHLEAEIVETKDEKGEVE 1147

Query: 241  KDI-ESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQS 299
            + + E + +  ++ +  N L    R          ++  E               L  + 
Sbjct: 1148 RRVWELQTIIDNNTKFVNDLQTELRSNYKQMEQLKSKHAEDTQLQNQRLETVIEELTAKM 1207

Query: 300  IEPSCEE-KTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKA 358
             E  CE  K E+E+K  L   N+TE  K    LE     + +  K+ E K+     + K 
Sbjct: 1208 RE--CEILKEELEQKERLIGRNVTEEAKVA--LESKVADLEKRLKDSEEKVQLQLEKMKK 1263

Query: 359  VSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLN 418
            +++  KK + +      R   ++++  W      T  +D +K+    +I  +E+ I+  +
Sbjct: 1264 IAANLKKKTAVCQELETR--VAELEEKW------TTEKD-EKEAKNKQIQDVEITIREKD 1314

Query: 419  KDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEI 478
              + D E  +++                T  + L+    + M   SL       E+  EI
Sbjct: 1315 NRIADLEEKLAQSRNESSQASKNIERLTTDSSNLK----EKMA--SLTQQIAEMEE--EI 1366

Query: 479  AKVQEQLKQELNDEIKDVNVKDLIE-KLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKL 537
             K++  L+    D   +   + L+  + +S   Q+ Q N+        M +      +++
Sbjct: 1367 VKLRVDLESSTTDLTLEKESRQLVSSEYESYRRQVVQENERRQLELDEMKEKARELSVRM 1426

Query: 538  KQMQ-KTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIES 596
            + M+ + +++ + ++D   E   L  +  H+++K+  +E+E    +L L   +   ++ +
Sbjct: 1427 QVMEAEYVEHLTLINDLKAENGLLLSKQAHINEKLETVEKESEERRLLLEQLEKAAVVNT 1486

Query: 597  --DVYKKMIEMENLAETRLKAISLLE-----SQKFDLVQELHI-LQQKYDEVED------ 642
              +  +   E E   E   K    L+      Q   LVQ L   LQ++  E+E+      
Sbjct: 1487 RAEATQTQGEEEMANEDEGKTSGALQHCTHCEQCQTLVQALEAKLQEREAEIENLDNELA 1546

Query: 643  -KLADISQLQSDQVCSEI------KSVHLEE-------QIDALSASKKELALVIENLKLD 688
              + +  Q++     +++      ++  LE+       Q ++L++S +E+ + +E    +
Sbjct: 1547 NSIGNFVQMRESLRFNDLMNQTGMRNRTLEDPYNDLLFQYNSLASSHEEVKVSLEKASRE 1606

Query: 689  KEQLYGTIKDLE--NDK-EDIMNKLQNYIQENMDLTDKLEKMSAEKIS-----ELLAKIN 740
             E+L GT+  L   ND  ++ +  L+N    N DL  K E+   E ++     E++ +  
Sbjct: 1607 NEELRGTVDQLRVTNDTFQERITTLENVDALNSDLVKKWEERERELLNARQELEIVQRRG 1666

Query: 741  HEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKAD 800
             E + ++  Q      ++ R    E  E  L   K  + R  ES+ + +D   S ERK  
Sbjct: 1667 DELERRLNAQAESLKSVEARR---EAAEKSLRDTKESLEREIESLRMDKD---SSERKMK 1720

Query: 801  QLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHE---NKELQKKNQI 857
             L + L   +   S      D        L D  R+       ++ E   ++E  K+ + 
Sbjct: 1721 DLETELDAWRSRESFDAPPRDNAPQ----LFDASRIFGSAPSPLDSEPLADREEVKRLRS 1776

Query: 858  LLEENQNLQISLS-DMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQT 916
            LLEE +    +L+ ++ Q    L E+    +  ++   +  T L   E ++     + ++
Sbjct: 1777 LLEEREAQCSNLTQEVYQLQGTLSEERRLIEGLKASQKELSTNLERAERSVAEKEKQVES 1836

Query: 917  LIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQ-------LQEYKN 969
            L  + +     +E E    + +     K LN + +   E + +   +       L+ Y++
Sbjct: 1837 LDAELRNSTIRMEDELRESLSAKDEQLKELNARLDSVKETLEEALVERDRQHSLLRSYES 1896

Query: 970  NIENLNMNVEELNKMN-LELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQ-----KDE 1023
             I +L M +     ++ L+ ++K V    T+  D  +  +N++ +    LK      ++ 
Sbjct: 1897 QINDLEMELRNSTDLDALQDLEKRVLSL-TKERDLLQLQVNDLTRSMEELKDSINRGRNS 1955

Query: 1024 EIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQI 1083
            E+  + ++ + A+ +  S+    E    + + K    ++   + S +   SK     + +
Sbjct: 1956 EMEKVGRERDEARETIASLSRALEEARERQSDKATVTDDTSTKESLERRASKIEERSVSL 2015

Query: 1084 LVREQ-----DDQIK--ELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXX 1136
             V E      D++I     ++ +L  E  +  T  ++I ST   +    +  D       
Sbjct: 2016 DVGEMEKINVDEEIWGWNTEDAQLDSEQAMAST--ILIPSTEIQLRAKVD--DLQDQVKD 2071

Query: 1137 XXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQI 1196
                  ++ EE +  Q R+    +  K      E   + ++++    +  G D   +E++
Sbjct: 2072 LERERARMGEENKAAQLRNAKMLKKLKEYKAQAESLQQQLKIQKTAADFYGLDSAIEEEL 2131

Query: 1197 NQLKSKLEQ-LNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEH 1255
                 KLE+ LN   +   +TVAE       A+ +R   +    ++++  +E      E 
Sbjct: 2132 KSQIGKLEKNLNEVKEERRNTVAE-----KEALMKRLDVVVSANERYMEMKERQDMDME- 2185

Query: 1256 ELRVQLSAFESKYEQLLDSVQSST----QEETN---KIVTMEQVTSLQNKLQ-DKEEHLR 1307
             LR++      K E L   +Q ST    +++T+   K+ T EQ +S + K    KE  L 
Sbjct: 2186 VLRIRNKELSDKVEILDKRLQDSTFRLVEDDTSSEQKVATQEQASSSREKRSLPKEADLE 2245

Query: 1308 NLQEKYA----DVINQIEILRSE-------IEDEKV---AFXXXXXXXXXXXXXXXXDLR 1353
            +L ++Y     D+ +++E L +E       +E++K+   A                 DL 
Sbjct: 2246 SLSKRYKEEMDDLKDEMEALATENEQLQHFLEEQKIKLSALESKRSAEEDESIQIVDDLN 2305

Query: 1354 TENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKD 1413
             +    + +  +S    +    Q ++S               +  + +  E T +LE++ 
Sbjct: 2306 GKISELQAVLSKSREEYDLLRKQYEQSLMDANDQVTAMRQNADYLKEEAFERTAKLEMEI 2365

Query: 1414 SEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHY 1473
             ++ Q+     + +T+     E+  ++    E+R+ DLT   E +++ L   M E  +  
Sbjct: 2366 VDLRQQLEASELNVTELRKGLEDALREKSSVEERLTDLTASTEKQVSSLNASMLEVTDLL 2425

Query: 1474 ETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEI 1533
             T  +E    R +L ++          L   V E N+ L+E+  +  +++ +   +E E 
Sbjct: 2426 NTRIQEVADLRQELQKQYVEHEEAKTRLQSTVKESNRELDEKRQEMEDLRRSFAEREKEF 2485

Query: 1534 VTLNDEITNLQNMVRASSSKIQKH 1557
            V      T    + +A+   +Q+H
Sbjct: 2486 VERQSVETVSALVSQATQELMQRH 2509



 Score =  111 bits (268), Expect = 1e-22
 Identities = 275/1454 (18%), Positives = 600/1454 (41%), Gaps = 153/1454 (10%)

Query: 143  DVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXX 202
            ++  L  TI+EKD  L     +++    TI  LQ++ N    +I+ K+ + T        
Sbjct: 972  EIIRLKETIEEKDQELQAKYTELQNKMITIDSLQDEFNNCKMLIQEKDTSITSMTNEVAN 1031

Query: 203  XXXXXXXXXED---TKQQMTKMQENF-IAMEAEWKDEKQRLLKD----IESKDVRISSLE 254
                     E+    ++ +T++ +    ++  +  ++    LKD    ++  + RI++  
Sbjct: 1032 LNNLVKSKEEEIYSLRKNITELSDKLEQSIPVKDYNDLMEKLKDKNMIVDELECRINATT 1091

Query: 255  EANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKG 314
            + N  L      +S +++ +  +L +              L  + +E   +EK E+E + 
Sbjct: 1092 KENSNLSEKVKNLSQQNNDIQNQLTEKQRELVDLITTKDHLEAEIVETK-DEKGEVERR- 1149

Query: 315  SLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKS 374
              E+   T +    + +  L  ++R   K++E +L +   E   +   +++   +I    
Sbjct: 1150 VWEL--QTIIDNNTKFVNDLQTELRSNYKQME-QLKSKHAEDTQLQ--NQRLETVI---- 1200

Query: 375  GRNTASKMKSPWSQLSSETLNQDTDKKINKN--EIAK--LEMVIQSLNKDLVDKEYVISE 430
                 +KM+    ++  E L Q  ++ I +N  E AK  LE  +  L K L D E  + +
Sbjct: 1201 -EELTAKMRE--CEILKEELEQ-KERLIGRNVTEEAKVALESKVADLEKRLKDSEEKV-Q 1255

Query: 431  KDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELN 490
                          K T + Q +LE              T   ++ E    ++  K+  N
Sbjct: 1256 LQLEKMKKIAANLKKKTAVCQ-ELE--------------TRVAELEEKWTTEKDEKEAKN 1300

Query: 491  DEIKDV--NVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFS 548
             +I+DV   +++   ++   EE++ Q  +E   A+KN+ ++ ++    LK+   ++    
Sbjct: 1301 KQIQDVEITIREKDNRIADLEEKLAQSRNESSQASKNIERLTTDSS-NLKEKMASLT--Q 1357

Query: 549  KVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENL 608
            ++++  +EIV+L  +   L     +L  EK + QL   +Y+S        Y++ +  EN 
Sbjct: 1358 QIAEMEEEIVKLRVD---LESSTTDLTLEKESRQLVSSEYES--------YRRQVVQEN- 1405

Query: 609  AETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQI 668
             E R   +  ++ +  +L   + +++ +Y E    L  I+ L+++      K  H+ E++
Sbjct: 1406 -ERRQLELDEMKEKARELSVRMQVMEAEYVE---HLTLINDLKAENGLLLSKQAHINEKL 1461

Query: 669  DALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMS 728
            + +    +E  L++E L                +K  ++N      Q   +  +++    
Sbjct: 1462 ETVEKESEERRLLLEQL----------------EKAAVVNTRAEATQTQGE--EEMANED 1503

Query: 729  AEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVM 788
              K S  L    H EQ +   Q  ++AK+QER+  IEN+++EL+       ++ ES+   
Sbjct: 1504 EGKTSGALQHCTHCEQCQTLVQ-ALEAKLQEREAEIENLDNELANSIGNFVQMRESL--- 1559

Query: 789  EDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHEN 848
               R++     +Q G   +  +  Y++   Q + L +       H+  V+  L +   EN
Sbjct: 1560 ---RFN--DLMNQTGMRNRTLEDPYNDLLFQYNSLAS------SHEE-VKVSLEKASREN 1607

Query: 849  KELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLE---S 905
            +EL+     L   N   Q  ++ ++       +   + +  E E    + +L  ++    
Sbjct: 1608 EELRGTVDQLRVTNDTFQERITTLENVDALNSDLVKKWEERERELLNARQELEIVQRRGD 1667

Query: 906  NLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQ 965
             L+R  +     +   +   E  E       ES  R+ + L    + +   +  LE +L 
Sbjct: 1668 ELERRLNAQAESLKSVEARREAAEKSLRDTKESLEREIESLRMDKDSSERKMKDLETELD 1727

Query: 966  EYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYIN--EINKLNALLKQKDE 1023
             +++  E+ +    +      +L D         SP  +E   +  E+ +L +LL++++ 
Sbjct: 1728 AWRSR-ESFDAPPRDNAP---QLFDASRIFGSAPSPLDSEPLADREEVKRLRSLLEEREA 1783

Query: 1024 EIIALNQKINNAQVSYMS---MVSDYESKLAQFTTKLENMEEEMQRVSKQL--LDSKQHN 1078
            +   L Q++   Q +      ++   ++   + +T LE  E  +    KQ+  LD++  N
Sbjct: 1784 QCSNLTQEVYQLQGTLSEERRLIEGLKASQKELSTNLERAERSVAEKEKQVESLDAELRN 1843

Query: 1079 ------EELQILVREQDDQIKELK----ETKLTFEMNIPKTEGMIISSTIEPMSDDANNV 1128
                  +EL+  +  +D+Q+KEL       K T E  + + +     S +       N++
Sbjct: 1844 STIRMEDELRESLSAKDEQLKELNARLDSVKETLEEALVERDRQ--HSLLRSYESQINDL 1901

Query: 1129 DXXXXXXXXXXXXLKVQEEE-EFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTG 1187
            +              +++      +ER +LQ Q   L   ++E    I +      E  G
Sbjct: 1902 EMELRNSTDLDALQDLEKRVLSLTKERDLLQLQVNDLTRSMEELKDSINRGRNSEMEKVG 1961

Query: 1188 HDVVN-QEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQR 1246
             +    +E I  L   LE+   E  +  +TV +  +S   ++++R  +I E   + ++  
Sbjct: 1962 RERDEARETIASLSRALEEAR-ERQSDKATVTD-DTSTKESLERRASKIEE---RSVSLD 2016

Query: 1247 EADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKE-EH 1305
              + +K   +  +     E        ++ S+    + +I    +V  LQ++++D E E 
Sbjct: 2017 VGEMEKINVDEEIWGWNTEDAQLDSEQAMASTILIPSTEIQLRAKVDDLQDQVKDLERER 2076

Query: 1306 LRNLQEKYADVINQIEILR--SEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQ 1363
             R  +E  A  +   ++L+   E + +  +                 D   E +   Q+ 
Sbjct: 2077 ARMGEENKAAQLRNAKMLKKLKEYKAQAESLQQQLKIQKTAADFYGLDSAIEEELKSQIG 2136

Query: 1364 EQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEY 1423
            +    N+NE   + ++++             V  A  + +E+  + ++ D E+ +     
Sbjct: 2137 KLE-KNLNEVKEE-RRNTVAEKEALMKRLDVVVSANERYMEMKERQDM-DMEVLR----- 2188

Query: 1424 TITLTQRNDEFENVRQQLVEYEKR-IEDLTYEKESELAILRLKMHENANHYETMQKESEI 1482
             I   + +D+ E + ++L +   R +ED   +  SE  +   +   ++    ++ KE+++
Sbjct: 2189 -IRNKELSDKVEILDKRLQDSTFRLVED---DTSSEQKVATQEQASSSREKRSLPKEADL 2244

Query: 1483 ERV--KLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQ---TALENQEIEIV-TL 1536
            E +  +  EE++    E  +L  +  +L   LEE+  K + ++   +A E++ I+IV  L
Sbjct: 2245 ESLSKRYKEEMDDLKDEMEALATENEQLQHFLEEQKIKLSALESKRSAEEDESIQIVDDL 2304

Query: 1537 NDEITNLQNMVRAS 1550
            N +I+ LQ ++  S
Sbjct: 2305 NGKISELQAVLSKS 2318



 Score =  101 bits (243), Expect = 1e-19
 Identities = 186/978 (19%), Positives = 386/978 (39%), Gaps = 83/978 (8%)

Query: 638  DEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELA----LVIENLKLDKEQLY 693
            D  E+ + DISQ ++ +  S +    L E   A     KE++     V E ++  ++QL 
Sbjct: 67   DTPEENIDDISQAKTAKAKSTLLQKKLAENRKAFEQRNKEISETKRAVEEKVEAIRQQLE 126

Query: 694  G---TIKDLENDK------------EDIMNKLQ-----NYIQENMDLTDKLEKMSAEKIS 733
                T+   + D+             DIM+ +Q       +QEN+   D + +   + ++
Sbjct: 127  EKDVTVMAFQKDQISITAVKPVMITSDIMSPIQIETTIMDLQENLKEKDSVIESKTKAVT 186

Query: 734  ELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESEL-SKYKSRICRLEESIAVMEDRR 792
             + A ++   ++ + T      +++    +   +E+ L +K ++ + +L+E     +D+ 
Sbjct: 187  LMSADLSKRGKTTLDTLEDTKDEMRTMQEHFVLLETSLKNKNENLLMQLQE----RDDKI 242

Query: 793  YSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQ 852
              LE   D+    + E++   SE T   D   + +  L++    ++            L+
Sbjct: 243  VELEDSVDRFRKQINEQK--LSE-TASVDFSRSTMDTLVETKEAMKSMQENFVLMESSLK 299

Query: 853  KKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITH 912
             KN  LLE+ ++ ++ L++  +    L      + +           + +L+  +  I+ 
Sbjct: 300  AKNDNLLEQLKDYELKLAEANERVFKL-----ESGIGIVRDPTVDEFVAELQDKIVNISM 354

Query: 913  EHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIE-YVTQLEAQLQEYKNNI 971
                 IV+K   I    IE    +E   +  K L E+ +  ++  V  L  + +EY N I
Sbjct: 355  HGNGAIVEKDNRI----IELENLVEELKQSNKFLEEESKAELQKQVADLTLKNEEYSNKI 410

Query: 972  ENLNMNV----EELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIA 1027
             +L   V    EE N++  +L ++ + K+  +  D   + +   N++  L ++K    ++
Sbjct: 411  TDLENFVHKLEEEKNEITAKLPEEGIIKEDEKISDTNAELVRLGNQVALLEEEKGNLQLS 470

Query: 1028 L--NQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILV 1085
            L    ++  +   +   V D ESK++  T ++E   E +  +  Q LD  Q     +  +
Sbjct: 471  LVDFDELKASAGDWQERVVDLESKVSAQTKEIEMQIEAIATLENQKLDLLQELHMAKQEI 530

Query: 1086 REQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLK-- 1143
               + +  E +  ++T E+ +   E  +    I  M +++                ++  
Sbjct: 531  SSLEAENAESENLRVTAEIKVVDLEEQL--EAIHRMQNESKLESSSEVNSAELIKQVETL 588

Query: 1144 VQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLE--TLNTELTGHDVVNQEQI----- 1196
             QE  E     S  +E+    +T   E +  I +L+   L  E    D  + E       
Sbjct: 589  TQENTELYNRISKFEEKGTS-DTGSTESFEAIQELDKTDLVEEKGSSDTGSTESFERIPE 647

Query: 1197 -NQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEI---AELWKQHLAQREADFQK 1252
             N+  +K+E L  EN  L+  + +L   +     +   ++    +  + H          
Sbjct: 648  NNESMTKIELLTQENSELVIKLTKLEEQLEYIESKSDIDLKLKIDTLELHKEIEMLSINN 707

Query: 1253 TEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEK 1312
            T+  +       E+K  +  +  +     +T   + ME+   LQ ++++    L    EK
Sbjct: 708  TDLTIEPHKLEIETKQSEESEISKRDVDFKTQVNILMEEKDLLQKEVKELRNSLEQWHEK 767

Query: 1313 YADVINQIEILRSEIED-----EKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSI 1367
              D+  QI  LR++IE+     E+V                     TE      +++Q+I
Sbjct: 768  NQDL--QINDLRTKIEELLRENEEVVTKMSELKTSNQKLEENTLKLTEKLDKLNLEKQNI 825

Query: 1368 LNINEENAQ----LKKSSXXXXXXXXXXXXRVNDAEAKVL-ELTHQLELKDSEIYQKT-- 1420
                + + Q    L+KS                  E+ ++  L  ++E   + I ++T  
Sbjct: 826  QEKKQLDEQIDIPLEKSDQELLKTPQLDEPLSQQTESTIVASLEQEIEKCKNLIAEQTGL 885

Query: 1421 -HEYTITLTQRNDEFENVRQQLVEYE---KRIEDLTYEKESELAILRLKMHENANHYETM 1476
              E  I L  +  E E   QQ+V+ E   K++E L  E     + +  +     N  E  
Sbjct: 886  IEEMKIKLVNKEKELEEKSQQIVDCERSGKKVETLENELREMFSTIE-EWRYKCNEMEEK 944

Query: 1477 QKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTL 1536
             ++ E   V    +L  +I+       ++  L + +EE+  +     T L+N+ I I +L
Sbjct: 945  MEKLEDTTVTFESKLERQISIISEKENEIIRLKETIEEKDQELQAKYTELQNKMITIDSL 1004

Query: 1537 NDEITNLQNMVRASSSKI 1554
             DE  N + +++   + I
Sbjct: 1005 QDEFNNCKMLIQEKDTSI 1022



 Score = 88.2 bits (209), Expect = 2e-15
 Identities = 185/1025 (18%), Positives = 413/1025 (40%), Gaps = 90/1025 (8%)

Query: 606  ENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQL--QSDQVCSEIKSVH 663
            +++A     A++    +  D + +    + K   ++ KLA+  +   Q ++  SE K   
Sbjct: 55   KDIARISETALTDTPEENIDDISQAKTAKAKSTLLQKKLAENRKAFEQRNKEISETKRA- 113

Query: 664  LEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNY-----IQENM 718
            +EE+++A+    +E  + +  +   K+Q+  T         DIM+ +Q       +QEN+
Sbjct: 114  VEEKVEAIRQQLEEKDVTV--MAFQKDQISITAVKPVMITSDIMSPIQIETTIMDLQENL 171

Query: 719  DLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESEL-SKYKSR 777
               D + +   + ++ + A ++   ++ + T      +++    +   +E+ L +K ++ 
Sbjct: 172  KEKDSVIESKTKAVTLMSADLSKRGKTTLDTLEDTKDEMRTMQEHFVLLETSLKNKNENL 231

Query: 778  ICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVV 837
            + +L+E     +D+   LE   D+    + E++   SE T   D   + +  L++    +
Sbjct: 232  LMQLQER----DDKIVELEDSVDRFRKQINEQK--LSE-TASVDFSRSTMDTLVETKEAM 284

Query: 838  EKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQ 897
            +            L+ KN  LLE+ ++ ++ L++  +    L      + +         
Sbjct: 285  KSMQENFVLMESSLKAKNDNLLEQLKDYELKLAEANERVFKL-----ESGIGIVRDPTVD 339

Query: 898  TQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIE-Y 956
              + +L+  +  I+      IV+K   I    IE    +E   +  K L E+ +  ++  
Sbjct: 340  EFVAELQDKIVNISMHGNGAIVEKDNRI----IELENLVEELKQSNKFLEEESKAELQKQ 395

Query: 957  VTQLEAQLQEYKNNIENLNMNV----EELNKMNLELIDKHVQKQQTQSPDYTEQYINEIN 1012
            V  L  + +EY N I +L   V    EE N++  +L ++ + K+  +  D   + +   N
Sbjct: 396  VADLTLKNEEYSNKITDLENFVHKLEEEKNEITAKLPEEGIIKEDEKISDTNAELVRLGN 455

Query: 1013 KLNALLKQKDEEIIALNQ--KINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQ 1070
            ++  L ++K    ++L    ++  +   +   V D ESK++  T ++E   E +  +  Q
Sbjct: 456  QVALLEEEKGNLQLSLVDFDELKASAGDWQERVVDLESKVSAQTKEIEMQIEAIATLENQ 515

Query: 1071 LLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDX 1130
             LD  Q     +  +   + +  E +  ++T E+ +   E  +    I  M +++     
Sbjct: 516  KLDLLQELHMAKQEISSLEAENAESENLRVTAEIKVVDLEEQL--EAIHRMQNESKLESS 573

Query: 1131 XXXXXXXXXXXLKV--QEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLET--LNTELT 1186
                       ++   QE  E     S  +E+    +T   E +  I +L+   L  E  
Sbjct: 574  SEVNSAELIKQVETLTQENTELYNRISKFEEKGTS-DTGSTESFEAIQELDKTDLVEEKG 632

Query: 1187 GHDVVNQEQI------NQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIA---E 1237
              D  + E        N+  +K+E L  EN  L+  + +L   +     +   ++    +
Sbjct: 633  SSDTGSTESFERIPENNESMTKIELLTQENSELVIKLTKLEEQLEYIESKSDIDLKLKID 692

Query: 1238 LWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQN 1297
              + H          T+  +       E+K  +  +  +     +T   + ME+   LQ 
Sbjct: 693  TLELHKEIEMLSINNTDLTIEPHKLEIETKQSEESEISKRDVDFKTQVNILMEEKDLLQK 752

Query: 1298 KLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQ 1357
            ++++    L    EK  D+  QI  LR++IE+                     +L+T NQ
Sbjct: 753  EVKELRNSLEQWHEKNQDL--QINDLRTKIEE--------LLRENEEVVTKMSELKTSNQ 802

Query: 1358 SYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLE--LTHQLELKDSE 1415
                  E++ L + E+  +L                + N  E K L+  +   LE  D E
Sbjct: 803  KL----EENTLKLTEKLDKLNLE-------------KQNIQEKKQLDEQIDIPLEKSDQE 845

Query: 1416 IYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYET 1475
            +  KT +    L+Q+ +    +   L +  ++ ++L  E+   +  +++K+    N  + 
Sbjct: 846  LL-KTPQLDEPLSQQTES--TIVASLEQEIEKCKNLIAEQTGLIEEMKIKL---VNKEKE 899

Query: 1476 MQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVT 1535
            ++++S+  ++   E    K+    +L  ++ E+   +EE   K NEM+  +E  E   VT
Sbjct: 900  LEEKSQ--QIVDCERSGKKVE---TLENELREMFSTIEEWRYKCNEMEEKMEKLEDTTVT 954

Query: 1536 LNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDLAMYM 1595
               ++    +++    ++I +      +  Q    +     NK +     + E +    +
Sbjct: 955  FESKLERQISIISEKENEIIRLKETIEEKDQELQAKYTELQNKMITIDSLQDEFNNCKML 1014

Query: 1596 LHQRD 1600
            + ++D
Sbjct: 1015 IQEKD 1019



 Score = 79.4 bits (187), Expect = 8e-13
 Identities = 188/1000 (18%), Positives = 413/1000 (41%), Gaps = 80/1000 (8%)

Query: 147  LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXX 206
            L + ++E+   LS L+ K    E   + + + +N K   ++A     +            
Sbjct: 2272 LQHFLEEQKIKLSALESKRSAEEDESIQIVDDLNGKISELQA---VLSKSREEYDLLRKQ 2328

Query: 207  XXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFE 266
                  D   Q+T M++N   ++ E  +   +L  ++E  D+R        + LEA+   
Sbjct: 2329 YEQSLMDANDQVTAMRQNADYLKEEAFERTAKL--EMEIVDLR--------QQLEASELN 2378

Query: 267  ISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQ--SIEPSCEEKTEIEEKGSLEIANMTEL 324
            ++     L   L +                KQ  S+  S  E T++      E+A++ + 
Sbjct: 2379 VTELRKGLEDALREKSSVEERLTDLTASTEKQVSSLNASMLEVTDLLNTRIQEVADLRQE 2438

Query: 325  TKKIELLEH------LNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNT 378
             +K + +EH      L   ++++N+EL+ K   M    ++ +   K+    + R+S    
Sbjct: 2439 LQK-QYVEHEEAKTRLQSTVKESNRELDEKRQEMEDLRRSFAEREKE---FVERQSVETV 2494

Query: 379  ASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXX 438
            ++ +    SQ + E + +      +  EI + +  +++LN+ L   E   +E        
Sbjct: 2495 SALV----SQATQELMQR------HAIEIEERDKHVRNLNERLSALEATANE---CLLEK 2541

Query: 439  XXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNE-IAKVQEQLKQ-ELNDEIKDV 496
                   D  I +L+L  +  ME  S +        V E  A +++QL Q EL    ++ 
Sbjct: 2542 RNNVVQLDARIQELELLRRDLMEKESSL------ASVREGFASMEKQLAQRELELSEREE 2595

Query: 497  NVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKE 556
             ++ L  + +   E + +L   ++ +      V + + L+++ +++ ++N   + D  + 
Sbjct: 2596 TIRKLSLENQRCVETVEELRKRLNESATISANV-NEYTLRVQTLEREVENMRSLLDEKEA 2654

Query: 557  IVRLT-EELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKA 615
            I+R   EE     + + +   E   L++ +   +    +++++ +K  E  N   + L+A
Sbjct: 2655 ILRKNVEEATEYREIIEKSRIELSELRMEVQKVED---LKNELLEKE-ERVNSLNSELEA 2710

Query: 616  I-SLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEE-QIDALSA 673
                LE  + +L +++ +L      + ++  +I +L S Q      +  ++   +  +  
Sbjct: 2711 TRKALEETRQNLNEKMSLLDHSNRLLNERQMEIDRLSSLQQDRRSSANMIDGLPVFRMGN 2770

Query: 674  SKKELALVIENLKLDKEQ--LYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEK 731
             ++ L   I+N+++ +    LY    +LE+    I  + +   ++   L  ++E  S E 
Sbjct: 2771 GEQNLQHTIDNMQMQQRIHCLYNEKAELESSLLVINARAEEKEKQIHALEQRIETQSQEF 2830

Query: 732  ISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAV---M 788
            +S+   +++  ++  IQ Q  I  ++Q  +LY +  E E+++ K  +   E  ++V   M
Sbjct: 2831 VSK--EELHSRDRRSIQEQEQI-VRLQN-ELYAK--EQEINELKYIVAEKESQLSVQASM 2884

Query: 789  EDR--RYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEH 846
            E +   + L     +L + L  K++      +   EL   ++ L + +R  E+    ++ 
Sbjct: 2885 EPQSDEFELREMVQRLTAELYGKEEEVKHTKLTIVELQREVSRLQEFERFSEQTREAVQK 2944

Query: 847  ENKELQKKNQILLEENQNLQISLSDMQQHYNALVEK-ANRTDLAESESTKYQTQLRDLES 905
             N E   K QI LE  + L+  L + +   + +    A        E +     +  L+S
Sbjct: 2945 LNAE---KEQIRLEGEEFLERRLKEKEMEIDEIKRNLAMENQKILDELSFNNRDIESLKS 3001

Query: 906  NLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQ 965
             L  ++   Q    + ++  EDL +  N+ +  A + +++      K+ E +  L+ Q+ 
Sbjct: 3002 QLTELSTTEQRTKDELRRREEDL-LRVNSDL--AEKKRRLAELSITKDAE-LHNLKIQIS 3057

Query: 966  EYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYT--EQYINEINKLNALLKQKDE 1023
            E    IE L    EE  K   EL +    ++   +   T  E  + E   +  +LK KD 
Sbjct: 3058 EKDARIEELVSLYEEGEKRFTELKNTLSAREIEINSLKTLLEDKVKEYQLIQNVLK-KDV 3116

Query: 1024 EIIALNQKINN--AQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEEL 1081
             ++  +    N   + S     +    +L      L   +   + ++ +L+   +  + L
Sbjct: 3117 SVLDTSTSTTNPNTETSDDKSKTSTSQELDLALYMLHQRDVRCEELTHELMQLLEERDTL 3176

Query: 1082 QILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPM 1121
            Q+ +       ++L++  LT     PK E      T+EP+
Sbjct: 3177 QLRLSNAIRVNEDLRKGTLTNVDLSPKMEPSTSGGTVEPI 3216


>UniRef50_A0BMM9 Cluster: Chromosome undetermined scaffold_117, whole
            genome shotgun sequence; n=1; Paramecium tetraurelia|Rep:
            Chromosome undetermined scaffold_117, whole genome
            shotgun sequence - Paramecium tetraurelia
          Length = 2732

 Score =  192 bits (467), Expect = 9e-47
 Identities = 282/1393 (20%), Positives = 596/1393 (42%), Gaps = 132/1393 (9%)

Query: 216  QQMTKMQENFIAMEAEWKDEKQRLLKDI--ESKDVRISSLEEANKLLEAARFEISLEHSK 273
            Q++  +QEN + M  + K  + ++ +++  E+K+      E    + E  + ++ L+ S+
Sbjct: 100  QKIQDLQENLVIMSDQMKFRESKIREEVQQETKETSEFGNERVKLITELRKCQVDLQESQ 159

Query: 274  L--AQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELL 331
               A +  Q              L+K  I+   ++  E+EEK       + +L +KIE L
Sbjct: 160  KQNANKFSQIQQLTNKATQIQN-LSKLEIDKLKQQNQELEEKLLQSQQKVDQLAQKIEEL 218

Query: 332  EHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWS---Q 388
            + LN Q+   ++E+E+    +  E +       +   + +R+   +   ++K   +   Q
Sbjct: 219  KELNSQLNLQSQEVEDVKQKLEKEFQQ-RYDEVEFEIINNRQIIEDLQIQLKELKALNLQ 277

Query: 389  LSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTL 448
            L S  +N   D K   + +      +Q+ N++L  K   +  K             +   
Sbjct: 278  LESAAINGTFDMKQQISLLQDQTNELQNQNQELQQK---LHAKQIEFDQMNKAKSREIEK 334

Query: 449  IAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSA 508
            + Q ++E QQ +E          T+ ++E    Q Q + E N + + + ++D   K + +
Sbjct: 335  LKQDKIELQQELE---------QTKQISE----QTQAETESNYKNQMLILQD---KFQKS 378

Query: 509  EEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLS 568
            EEQ ++LN +I   + ++I+ +  +K    Q+             N  I +  +EL   S
Sbjct: 379  EEQTSKLNQKIQELSADLIQERMLYKNNESQL-------------NGVITQQKDELSQKS 425

Query: 569  QKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRL-KAISLLESQKFDLV 627
              V +L E+   LQ H +  ++      D YK +++  N   T+L + I  L+ Q+    
Sbjct: 426  SLVLQLTEKIRILQDHSMQQETNISKNIDDYKVLLDQNNQQITQLSEQIKSLKKQQRQQE 485

Query: 628  QE-LHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLK 686
            QE   ++ Q   +++  LA+I+Q +          +   E  +    S+ +L+ +IE  K
Sbjct: 486  QENKQVISQYEQQIKQYLAEITQTK----------IQKNESDNQRQNSESQLSQIIEKQK 535

Query: 687  LDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSK 746
            +  +Q    I+DL N  E     +Q+  ++ M +    + +  EK S+    IN  E   
Sbjct: 536  VQLQQANAIIQDLNNQIEQFQQNIQDQEEQRMSVISVKQSLLIEKESQ----INMLESQV 591

Query: 747  IQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLG--- 803
            I+ Q  +  K  +  +  +  E + S +   I   E++  +   +   L+ K   L    
Sbjct: 592  IKYQNELTQKQDQIIILQQQYEKQKSDFNLAISEKEKNAKLTNQQHQELQNKVSDLTFEV 651

Query: 804  ---SYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLE 860
                 L +K +   E  IQ+    N+   L D        + E++   KE   K Q+ L+
Sbjct: 652  NQLRSLVDKAEVDKESNIQQYNEANQ--QLKDQLNTQNSLIQELQEYLKESNSKEQLALQ 709

Query: 861  ENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQ 920
            ++    + ++ +Q     L     + DL++ E  + QT L +    LK    +++TL   
Sbjct: 710  KSTQQSLEINQLQLEIGKL-----KNDLSQQEQKQSQTNLEN-SYKLKEQQTQNETLKND 763

Query: 921  KK--KEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNV 978
             K  + ++D   + N Q+   I D ++  ++ ++N++  TQ+    +  K  ++ LN  +
Sbjct: 764  FKQIQLVQDKLKQENFQLNEQINDLQIKLQESQENLKQTTQIN---ENQKEQLQKLNDQL 820

Query: 979  -EELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKL-NALLKQKDEEIIALNQKINNAQ 1036
             +E  K ++   +K   +Q  Q        ++E NKL  ++ + KD++I AL ++  +AQ
Sbjct: 821  YQEQQKESVNQTEKFYLQQLIQQHKDQVNEVHEKNKLITSISESKDKQIEALKKQGEDAQ 880

Query: 1037 VSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQ--LLDSKQHNEELQILVREQDDQIKE 1094
              Y            Q  T+ E M +  Q+  +Q  +LD     +E + L+ E  ++I  
Sbjct: 881  KHYEQ----------QKQTQYEEMVQLKQKYEQQFHILD-----DEKKSLIAEYTNRIAN 925

Query: 1095 LKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQER 1154
            L+E    ++ N    +        E ++     +D             ++Q + E  Q++
Sbjct: 926  LEEINNDYQKNSSIEQSQF---NQEKLNLKQQLLDQQVKIEKQLKEIEQMQGQLE--QKQ 980

Query: 1155 SVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLL 1214
              + + + K   E+ +   +++QL+ LNT+    + +N+  +  +     Q+N ++D   
Sbjct: 981  QEIIQINLKNECEVLQLSEELVQLKQLNTKQV--EEINERDL-MITLHQTQINLQDDQFR 1037

Query: 1215 STVAELRSSISSAVDQRGFEIAELWKQH---LAQREADFQKTEHELR---VQLSAFESKY 1268
              ++ L   I + + +   +I ++   H   L Q++ + Q  E++++    QL  ++++ 
Sbjct: 1038 LEISNLNVKIDNILKENQIQIEDIHSNHQKQLLQKQNEIQDKEYQIKKLDQQLFDYQAQM 1097

Query: 1269 EQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILR--SE 1326
            EQ L+ +Q   ++E  K+     V  L+N  Q KE+ +  L+    ++  ++E  +  S+
Sbjct: 1098 EQRLEYIQQK-EQEVEKLSQHNDV--LENDAQQKEQEIIQLKNHSQNLSVELEKFKQYSQ 1154

Query: 1327 IEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXX 1386
            +E EK                   +L+   Q +KQ  +    ++ ++   L++       
Sbjct: 1155 LEQEK---------QQQVILELTENLKQSEQLFKQQNK----SMEDQIKSLEQQITNQNQ 1201

Query: 1387 XXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEK 1446
                    +N    K  EL ++ +LK++E  ++  E       +N+  ++  Q  VE   
Sbjct: 1202 KIVQLQDSINQLNQKYQELKNEKQLKEAEYEKQLQELQNQSDIQNEAIDSQIQTNVEQSD 1261

Query: 1447 RIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVA 1506
            +I  L   K   L  L+  + E     E   K++ IE +K +++   +I E    N+ + 
Sbjct: 1262 QISKLEQNKSQLLEELQ-NVVEEKKQVELTYKQA-IEDLKTVQD--QRIAEINKKNQDLV 1317

Query: 1507 EL-NKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTK 1565
            +L N  L ++  +  E++  L+  + + +   +   +LQ   R   +K  +++      +
Sbjct: 1318 QLKNMILIQKDEELEELRQQLQQSQEDFIKQQNLNDSLQIHSRELKNKFDEYIETKFSEE 1377

Query: 1566 QGRDEQLDNTMNK 1578
            +  + +LD T  K
Sbjct: 1378 KRLNNELDLTEQK 1390



 Score =  173 bits (422), Expect = 3e-41
 Identities = 285/1491 (19%), Positives = 645/1491 (43%), Gaps = 113/1491 (7%)

Query: 146  HLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXX 205
            H  N   E +      Q++ +  +  IL+L E + + +Q+ + +NK+             
Sbjct: 1138 HSQNLSVELEKFKQYSQLEQEKQQQVILELTENLKQSEQLFKQQNKSMEDQIKSLEQQIT 1197

Query: 206  XXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARF 265
                     +  + ++ + +     E K+EKQ    + E +   + +  +       ++ 
Sbjct: 1198 NQNQKIVQLQDSINQLNQKY----QELKNEKQLKEAEYEKQLQELQNQSDIQNEAIDSQI 1253

Query: 266  EISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELT 325
            + ++E S    +LEQ                KQ +E +   K  IE+  +++   + E+ 
Sbjct: 1254 QTNVEQSDQISKLEQNKSQLLEELQNVVEEKKQ-VELTY--KQAIEDLKTVQDQRIAEIN 1310

Query: 326  KKIELLEHL-NCQIRQTNKELEN-KLATMGTESKAVSSPSKKGSPLISRKSGRNTASK-M 382
            KK + L  L N  + Q ++ELE  +     ++   +   +   S  I  +  +N   + +
Sbjct: 1311 KKNQDLVQLKNMILIQKDEELEELRQQLQQSQEDFIKQQNLNDSLQIHSRELKNKFDEYI 1370

Query: 383  KSPWSQLSSETLNQD---TDKKINK--NEIAKLEMVIQSLNKDLV--DKEYVI--SEKDT 433
            ++ +S+   + LN +   T++KIN+   ++ +    IQ+L  D+   D EY+   S+  T
Sbjct: 1371 ETKFSE--EKRLNNELDLTEQKINELQEQVDQHAETIQNLQGDIQRKDLEYLQLQSQLQT 1428

Query: 434  XXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVN-EIAKVQEQLKQELNDE 492
                           + + QL+HQ  +             D+N +I + +E++++  N  
Sbjct: 1429 KIQQHTLELSDLGGKMNEEQLKHQIEINQKQ-----QEISDLNFQIQEGKEKIEELSNII 1483

Query: 493  I-KDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVS 551
            I K+  +K L E ++    Q+ Q + +I    K++  +   ++ K KQ++++      + 
Sbjct: 1484 IDKETMIKSLEETIEGNTNQVQQQSIKIQEHQKSIEGLTLENQNKQKQLEQSA---KIIK 1540

Query: 552  DSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAET 611
            D+  E+  LT +L    +K  ++E     LQ         + +E ++Y   ++   L ET
Sbjct: 1541 DTQIELEELTTQLTDQIEKFNQIEGSYLKLQ------QQNKSLE-ELYNNTLK---LLET 1590

Query: 612  RLKAISLLESQKFDLVQELHI-LQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEE-QID 669
            + + ++    QK + +  +H+ L++   E E +   +     +Q+  ++  +  ++ +ID
Sbjct: 1591 KEEDLTTTVIQKNEEIASIHLSLEKLKQESEKEYKQLEDYSYEQLLKKMDDIAQKDWEID 1650

Query: 670  ALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSA 729
             L+   ++L    + L+   E +    K+ +N  ++I        Q++ ++ +  E +  
Sbjct: 1651 QLNQVVQDLN---QKLQAGMECVEQYDKEFDNQIKEIDELKSKIKQKDKEIKECNEIIEK 1707

Query: 730  EKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVME 789
            +K+          E+ ++ TQ  +       DL ++   + L+K +++I  L+  IA  +
Sbjct: 1708 QKLEIEAVNKQMNEELQLVTQ-SLQENQSNYDLELQAKLAILNKKEAQILNLDFQIAEFQ 1766

Query: 790  DRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENK 849
                +L ++ DQ+   +QE+        + EDE            + +++ L E E    
Sbjct: 1767 Q---NLNQQKDQIEELVQERNVLIERQKLIEDEKNQSDKEFKQQIQSLKESLSEFEENYN 1823

Query: 850  ELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRT--DLA---ESESTKYQTQLRDLE 904
             L+++++ +  +  + +   +D+QQ Y    E + +   DL    + ++ ++Q  +++ +
Sbjct: 1824 YLKQQHEEVQNQFASQKELYNDLQQKYEEDQESSQQLIQDLQSQKDKQNIEFQKYIKESD 1883

Query: 905  SNLKRITH----------EHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNI 954
             N+++  +          + Q LI   +  +ED   + + Q +     +  LN+   +  
Sbjct: 1884 LNIQKANNKINQKEEKIAQQQHLIETLQSNLEDKNQQHDEQGQRLFEKQNELNQVILEKQ 1943

Query: 955  EYVTQLEAQLQEYKNNIENLNMNVEELNKM-NLELIDK-HVQKQQTQSPDYTEQYINE-- 1010
                +L  Q+QE  N I + N+ V +L+++  L+  +K  + KQ  Q+ D  +Q + +  
Sbjct: 1944 TNEKKLSQQIQECNNKIASYNLEVAQLSQLITLKESEKSQLSKQFEQTSDQLKQQLFQQT 2003

Query: 1011 --INKLNALLKQKDEEIIALNQKIN--NAQVSYMSM-VSDYESKLAQFTTKLENMEEEMQ 1065
              I +L   + +  E      QKIN  N Q+S +   +S+   ++ +    ++  +EE  
Sbjct: 2004 QFIQELQDYINESQENESKAGQKINTLNLQISTLEFEISNLNCEILKLQNTIKQSKEEKL 2063

Query: 1066 RVSKQ-LLDSKQHNEELQILVREQDDQIKELKETKLTF---EMNI-PKTEGMIISSTIEP 1120
            R+ +    D  Q  ++LQ  +        E ++ ++     E N+  K E  +    I  
Sbjct: 2064 RLEEDHQQDIIQIQQQLQAAISANQLLKNEAQKKQINLFENEQNLNSKIEQQVYEIKILK 2123

Query: 1121 MSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQ--- 1177
                   ++                E  + ++++ +  + SA    E+++   + +Q   
Sbjct: 2124 EEIQRLQLEMQRQVKESDSNLNNKNEMIDLLKKQLIDIQNSAANAEEMKDLIQRQLQDQS 2183

Query: 1178 ---LETLNTELTGHD--VVN-QEQINQL---KSKLEQLNTENDNLLSTVAELRSSISSAV 1228
                + LN ++   D  + N ++QI QL   K + EQL TE  ++L+     ++   + +
Sbjct: 2184 QSQAQQLNQQIKTRDDQITNLKQQIQQLSQSKQQQEQLLTEQISVLNQQIRSKNESMNQL 2243

Query: 1229 DQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFES-KYEQLLDSVQSSTQEETNKIV 1287
            D    E  + +K  + Q      + + E++   S  +S K +Q  + +    +E  NKI 
Sbjct: 2244 D----ESIKYFKSQIDQSNLTITQLQQEIQSLNSKLQSSKNDQ--NQINEENKELQNKIE 2297

Query: 1288 TMEQVTSL-QNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVA-FXXXXXXXXXXX 1345
             ++Q+++  Q++L+  ++ +  L+E+      QI+ L S+I D+                
Sbjct: 2298 IVQQISNTAQSELEKLKQQILKLEEEKQRQSEQIKQLSSQINDQNSQNLQITQKLLSQKE 2357

Query: 1346 XXXXXDLRTEN--QSYKQMQEQS---ILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEA 1400
                 DL+ +N  + Y+Q +EQS   I  +    +QL+++             + +++E 
Sbjct: 2358 EKELIDLQQKNIQEQYQQHREQSEKQIYQLTNNVSQLEQTLSEIQNNLLLVNKQKSESEE 2417

Query: 1401 KVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELA 1460
            K+ +L  QL+  +S++     +Y     Q+  +  N+ Q+  E ++ + +   E+ S+L 
Sbjct: 2418 KLNKLGQQLQNVNSQLSDSRDKYESENQQQLQQINNLSQENSELQQTLNE-KLEELSKLQ 2476

Query: 1461 ILRLKMHENANHYETMQKESEIERVKLIEELNVKITES--VSLNKQVAELNKALEEEVAK 1518
            +   K+ +N    + +  ES+++ +  ++E N K  E   + L  Q  EL +  E    +
Sbjct: 2477 LDNTKLVQNQKKVDKL--ESQVQELSALKEQNGKQIEQQELRLKSQQQELEQLRENYNLQ 2534

Query: 1519 TNEMQTA---LENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQ 1566
             N++ +    +   EI+   L+ EI  LQ+  +   S++QK+  + +  +Q
Sbjct: 2535 KNQLNSLNQQIAQYEIDKDKLSKEIKQLQSQNQNYLSQVQKYQDYINQQQQ 2585



 Score =  165 bits (400), Expect = 1e-38
 Identities = 300/1452 (20%), Positives = 625/1452 (43%), Gaps = 161/1452 (11%)

Query: 158  LSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQ 217
            +S+LQ +   ++    +LQ+K++ K    +  NKA +                     ++
Sbjct: 293  ISLLQDQTNELQNQNQELQQKLHAKQIEFDQMNKAKS---------------------RE 331

Query: 218  MTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH-SKLAQ 276
            + K++++ I ++ E +  KQ      E       S  +   L+   +F+ S E  SKL Q
Sbjct: 332  IEKLKQDKIELQQELEQTKQ----ISEQTQAETESNYKNQMLILQDKFQKSEEQTSKLNQ 387

Query: 277  ELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELL-EHLN 335
            ++++                 Q      ++K E+ +K SL    + +LT+KI +L +H  
Sbjct: 388  KIQELSADLIQERMLYKNNESQLNGVITQQKDELSQKSSL----VLQLTEKIRILQDHSM 443

Query: 336  CQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASK-MKSPWSQLSSETL 394
             Q    +K +++    +   ++ ++  S++   L  ++  +   +K + S + Q   + L
Sbjct: 444  QQETNISKNIDDYKVLLDQNNQQITQLSEQIKSLKKQQRQQEQENKQVISQYEQQIKQYL 503

Query: 395  NQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQL 454
             + T  KI KNE        +S    +++K+ V  ++              + +I  L  
Sbjct: 504  AEITQTKIQKNESDNQRQNSESQLSQIIEKQKVQLQQ-------------ANAIIQDLNN 550

Query: 455  EHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQ 514
            + +Q  +         N +D  E       +KQ L  E K+  +  L  ++   + ++TQ
Sbjct: 551  QIEQFQQ---------NIQDQEEQRMSVISVKQSLLIE-KESQINMLESQVIKYQNELTQ 600

Query: 515  LNDEIDAANKNMIKVKSNHKLKLKQMQKT--IDNFSKVSDSNKEIVRLTEELHHLSQKVA 572
              D+I    +   K KS+  L + + +K   + N       NK +  LT E++ L   V 
Sbjct: 601  KQDQIIILQQQYEKQKSDFNLAISEKEKNAKLTNQQHQELQNK-VSDLTFEVNQLRSLVD 659

Query: 573  ELEEEK-GNLQLHLVDYDSGRMIESDVYKKMIE--MENLAETRLK-AISLLESQKFDLVQ 628
            + E +K  N+Q +  + +     + +    +I+   E L E+  K  ++L +S +  L  
Sbjct: 660  KAEVDKESNIQQY-NEANQQLKDQLNTQNSLIQELQEYLKESNSKEQLALQKSTQQSL-- 716

Query: 629  ELHILQQKYDEVEDKLADISQLQSD-QVCSEIKSVHLEEQIDALSASKKELALVIENLKL 687
            E++ LQ +  ++++ L+   Q QS   + +  K    + Q + L    K++ LV + LK 
Sbjct: 717  EINQLQLEIGKLKNDLSQQEQKQSQTNLENSYKLKEQQTQNETLKNDFKQIQLVQDKLKQ 776

Query: 688  DKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKI 747
            +  QL   I DL+   ++    L+   Q N +  ++L+K++ +   E       +++S  
Sbjct: 777  ENFQLNEQINDLQIKLQESQENLKQTTQINENQKEQLQKLNDQLYQE------QQKESVN 830

Query: 748  QTQ-FGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERK--ADQLGS 804
            QT+ F +   IQ+    +  +  +         +L  SI+  +D++    +K   D    
Sbjct: 831  QTEKFYLQQLIQQHKDQVNEVHEK--------NKLITSISESKDKQIEALKKQGEDAQKH 882

Query: 805  YLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQN 864
            Y Q+KQ  Y E    + +   +  +L D     EK+ L  E+ N+        L E N +
Sbjct: 883  YEQQKQTQYEEMVQLKQKYEQQFHILDD-----EKKSLIAEYTNRIAN-----LEEINND 932

Query: 865  LQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLI-VQKKK 923
             Q + S  Q  +N   EK N       +  K + QL+++E    ++  + Q +I +  K 
Sbjct: 933  YQKNSSIEQSQFNQ--EKLNLKQQLLDQQVKIEKQLKEIEQMQGQLEQKQQEIIQINLKN 990

Query: 924  EIEDLEIEFNTQIESAIRDKKV--LNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEEL 981
            E E L++         +  K+V  +NE+      + TQ+  Q  +++  I NLN+ ++ +
Sbjct: 991  ECEVLQLSEELVQLKQLNTKQVEEINERDLMITLHQTQINLQDDQFRLEISNLNVKIDNI 1050

Query: 982  ---NKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVS 1038
               N++ +E I  + QKQ  Q         NEI      +K+ D+++     ++   ++ 
Sbjct: 1051 LKENQIQIEDIHSNHQKQLLQKQ-------NEIQDKEYQIKKLDQQLFDYQAQMEQ-RLE 1102

Query: 1039 YMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVR--EQDDQIKELK 1096
            Y+        KL+Q    LEN   + Q+  ++++  K H++ L + +   +Q  Q+++ K
Sbjct: 1103 YIQQKEQEVEKLSQHNDVLEN---DAQQKEQEIIQLKNHSQNLSVELEKFKQYSQLEQEK 1159

Query: 1097 ETKLTFEM--NIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLK---VQEEEEFI 1151
            + ++  E+  N+ ++E  +     + M D   +++            L+    Q  +++ 
Sbjct: 1160 QQQVILELTENLKQSE-QLFKQQNKSMEDQIKSLEQQITNQNQKIVQLQDSINQLNQKYQ 1218

Query: 1152 QERSVLQEQSAKLNTELQECYTKI-IQLETLNTELTGHDVVNQEQINQLKSKLEQLNTEN 1210
            + ++  Q + A+   +LQE   +  IQ E +++++   +V   +QI++L+    QL  E 
Sbjct: 1219 ELKNEKQLKEAEYEKQLQELQNQSDIQNEAIDSQIQ-TNVEQSDQISKLEQNKSQLLEEL 1277

Query: 1211 DNLLSTVAELRSSISSAVDQ----RGFEIAELWK--QHLAQRE--ADFQKTE--HELRVQ 1260
             N++    ++  +   A++     +   IAE+ K  Q L Q +     QK E   ELR Q
Sbjct: 1278 QNVVEEKKQVELTYKQAIEDLKTVQDQRIAEINKKNQDLVQLKNMILIQKDEELEELRQQ 1337

Query: 1261 LSAFES---KYEQLLDSVQSSTQEETNKI-----VTMEQVTSLQNKLQDKEEHLRNLQEK 1312
            L   +    K + L DS+Q  ++E  NK          +   L N+L   E+ +  LQE+
Sbjct: 1338 LQQSQEDFIKQQNLNDSLQIHSRELKNKFDEYIETKFSEEKRLNNELDLTEQKINELQEQ 1397

Query: 1313 YADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINE 1372
                   I+ L+ +I+ + + +                +L        + Q +  + IN+
Sbjct: 1398 VDQHAETIQNLQGDIQRKDLEYLQLQSQLQTKIQQHTLELSDLGGKMNEEQLKHQIEINQ 1457

Query: 1373 ENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRND 1432
            +  ++   +            ++ + + K+ EL++   + D E   K+ E TI       
Sbjct: 1458 KQQEISDLN-----------FQIQEGKEKIEELSN--IIIDKETMIKSLEETIEGNTNQV 1504

Query: 1433 EFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELN 1492
            + ++++ Q  E++K IE LT E +++    + ++ ++A   +  Q E E    +L +++ 
Sbjct: 1505 QQQSIKIQ--EHQKSIEGLTLENQNK----QKQLEQSAKIIKDTQIELEELTTQLTDQIE 1558

Query: 1493 VKITESVSLNKQVAELNKALEEEVAKTNE-MQTALENQEIEIVTLNDEITNLQNMVRASS 1551
             K  +      ++ + NK+LEE    T + ++T  E+    ++  N+EI ++   +    
Sbjct: 1559 -KFNQIEGSYLKLQQQNKSLEELYNNTLKLLETKEEDLTTTVIQKNEEIASIHLSLEKLK 1617

Query: 1552 SKIQKHVSFASD 1563
             + +K      D
Sbjct: 1618 QESEKEYKQLED 1629



 Score =  163 bits (396), Expect = 4e-38
 Identities = 295/1582 (18%), Positives = 683/1582 (43%), Gaps = 124/1582 (7%)

Query: 91   SESLANTLKQKEILMEKIKQYK-ELSKRSSTTIVRXXXXXXXXXXXXXXX--QLGDVTHL 147
            +E+L N  KQ +++ +K+KQ   +L+++ +   ++                 Q   +  L
Sbjct: 757  NETLKNDFKQIQLVQDKLKQENFQLNEQINDLQIKLQESQENLKQTTQINENQKEQLQKL 816

Query: 148  SNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXX 207
            ++ + ++    SV Q +   ++  I   ++++NE    +  KNK  T             
Sbjct: 817  NDQLYQEQQKESVNQTEKFYLQQLIQQHKDQVNE----VHEKNKLITSISESKDKQIEAL 872

Query: 208  XXXXEDTKQ--QMTKMQENFIAMEAEWKDEKQRLLKDIESKDV------RISSLEEAN-- 257
                ED ++  +  K  +    ++ + K E+Q  + D E K +      RI++LEE N  
Sbjct: 873  KKQGEDAQKHYEQQKQTQYEEMVQLKQKYEQQFHILDDEKKSLIAEYTNRIANLEEINND 932

Query: 258  --KLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGS 315
              K     + + + E   L Q+L                +  Q +E   +E  +I  K  
Sbjct: 933  YQKNSSIEQSQFNQEKLNLKQQLLDQQVKIEKQLKEIEQMQGQ-LEQKQQEIIQINLKNE 991

Query: 316  LEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSG 375
             E+  ++E     EL++      +Q  +E+  +   +      ++    +    IS  + 
Sbjct: 992  CEVLQLSE-----ELVQLKQLNTKQV-EEINERDLMITLHQTQINLQDDQFRLEISNLNV 1045

Query: 376  RNTASKMKSPWSQLSSETLNQDTDKKI--NKNEIAKLEMVIQSLNKDLVDKEYVISEKDT 433
            +   + +K   +Q+  E ++ +  K++   +NEI   E  I+ L++ L D +  + ++  
Sbjct: 1046 K-IDNILKE--NQIQIEDIHSNHQKQLLQKQNEIQDKEYQIKKLDQQLFDYQAQMEQRLE 1102

Query: 434  XXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVN-EIAKVQE--QLKQELN 490
                              L+ + QQ  +   +I +  ++++++ E+ K ++  QL+QE  
Sbjct: 1103 YIQQKEQEVEKLSQHNDVLENDAQQKEQ--EIIQLKNHSQNLSVELEKFKQYSQLEQEKQ 1160

Query: 491  DEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKV 550
             ++    + +L E LK +E+   Q N  ++   K++ +  +N   K+ Q+Q +I+  ++ 
Sbjct: 1161 QQV----ILELTENLKQSEQLFKQQNKSMEDQIKSLEQQITNQNQKIVQLQDSINQLNQK 1216

Query: 551  SDSNKEIVRLTE-----ELHHLSQKVAELEEEK--GNLQLHLVDYDSGRMIESDVYKKMI 603
                K   +L E     +L  L Q  ++++ E     +Q ++   D    +E +  + + 
Sbjct: 1217 YQELKNEKQLKEAEYEKQLQEL-QNQSDIQNEAIDSQIQTNVEQSDQISKLEQNKSQLLE 1275

Query: 604  EMENLAETRLKAISLLESQKFDLVQELHILQ-QKYDEVEDKLADISQL------QSDQVC 656
            E++N+ E + K + L   Q    +++L  +Q Q+  E+  K  D+ QL      Q D+  
Sbjct: 1276 ELQNVVEEK-KQVELTYKQA---IEDLKTVQDQRIAEINKKNQDLVQLKNMILIQKDEEL 1331

Query: 657  SEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQE 716
             E++    + Q D +       +L I + +L K +    I+   ++++ + N+L    Q+
Sbjct: 1332 EELRQQLQQSQEDFIKQQNLNDSLQIHSREL-KNKFDEYIETKFSEEKRLNNELDLTEQK 1390

Query: 717  NMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELS---- 772
              +L +++++  AE I  L   I  ++   +Q Q  +  KIQ+  L + ++  +++    
Sbjct: 1391 INELQEQVDQ-HAETIQNLQGDIQRKDLEYLQLQSQLQTKIQQHTLELSDLGGKMNEEQL 1449

Query: 773  KYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYS--EYTIQ--EDELVNRLA 828
            K++  I + ++ I+ +  +    + K ++L + + +K+      E TI+   +++  +  
Sbjct: 1450 KHQIEINQKQQEISDLNFQIQEGKEKIEELSNIIIDKETMIKSLEETIEGNTNQVQQQSI 1509

Query: 829  VLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDL 888
             + +H + +E   LE +++ K+L++  +I+    ++ QI L ++       +EK N+ + 
Sbjct: 1510 KIQEHQKSIEGLTLENQNKQKQLEQSAKII----KDTQIELEELTTQLTDQIEKFNQIEG 1565

Query: 889  AESESTKYQTQLRDLESNLKRI--THEHQ--TLIVQKKKEIEDLEIEFNTQIESAIRDKK 944
            +  +  +    L +L +N  ++  T E    T ++QK +EI  + +      + + ++ K
Sbjct: 1566 SYLKLQQQNKSLEELYNNTLKLLETKEEDLTTTVIQKNEEIASIHLSLEKLKQESEKEYK 1625

Query: 945  VLNE-KYE---KNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQS 1000
             L +  YE   K ++ + Q + ++ +    +++LN  ++   +  +E  DK    Q  + 
Sbjct: 1626 QLEDYSYEQLLKKMDDIAQKDWEIDQLNQVVQDLNQKLQAGMEC-VEQYDKEFDNQIKEI 1684

Query: 1001 PDYT---EQYINEINKLNALLKQKDEEIIALNQKINNA-QVSYMSMV---SDYESKLAQF 1053
             +     +Q   EI + N +++++  EI A+N+++N   Q+   S+    S+Y+ +L   
Sbjct: 1685 DELKSKIKQKDKEIKECNEIIEKQKLEIEAVNKQMNEELQLVTQSLQENQSNYDLELQAK 1744

Query: 1054 TTKLENMEEEMQRVSKQLLDSKQH----NEELQILVREQDDQIKELK-------ETKLTF 1102
               L   E ++  +  Q+ + +Q+     ++++ LV+E++  I+  K       ++   F
Sbjct: 1745 LAILNKKEAQILNLDFQIAEFQQNLNQQKDQIEELVQERNVLIERQKLIEDEKNQSDKEF 1804

Query: 1103 EMNIPKTEGMI--ISSTIEPMSDDANNVDXXXXXXXXXXXXL--KVQEEEEFIQER-SVL 1157
            +  I   +  +         +      V             L  K +E++E  Q+    L
Sbjct: 1805 KQQIQSLKESLSEFEENYNYLKQQHEEVQNQFASQKELYNDLQQKYEEDQESSQQLIQDL 1864

Query: 1158 QEQSAKLNTELQECYTKI-IQLETLNTELTG-HDVVNQEQ--INQLKSKLEQLNTENDNL 1213
            Q Q  K N E Q+   +  + ++  N ++    + + Q+Q  I  L+S LE  N ++D  
Sbjct: 1865 QSQKDKQNIEFQKYIKESDLNIQKANNKINQKEEKIAQQQHLIETLQSNLEDKNQQHDEQ 1924

Query: 1214 LSTVAELRSSISSAVDQRGFEIAELWKQ--HLAQREADFQKTEHELRVQLSAFESKYEQL 1271
               + E ++ ++  + ++     +L +Q      + A +     +L   ++  ES+  QL
Sbjct: 1925 GQRLFEKQNELNQVILEKQTNEKKLSQQIQECNNKIASYNLEVAQLSQLITLKESEKSQL 1984

Query: 1272 LDSVQSSTQEETNKIVTMEQ-VTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDE 1330
                + ++ +   ++    Q +  LQ+ + + +E+     +K   +  QI  L  EI + 
Sbjct: 1985 SKQFEQTSDQLKQQLFQQTQFIQELQDYINESQENESKAGQKINTLNLQISTLEFEISNL 2044

Query: 1331 KVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXX 1390
                                      Q   Q+Q+Q    I+  N  LK  +         
Sbjct: 2045 NCEILKLQNTIKQSKEEKLRLEEDHQQDIIQIQQQLQAAISA-NQLLKNEAQKKQINLFE 2103

Query: 1391 XXXRVNDA-EAKVLE---LTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEK 1446
                +N   E +V E   L  +++    E+ ++  E    L  +N+  + +++QL++ + 
Sbjct: 2104 NEQNLNSKIEQQVYEIKILKEEIQRLQLEMQRQVKESDSNLNNKNEMIDLLKKQLIDIQN 2163

Query: 1447 RIEDLTYEKESELAILRLKMHENAN--HYETMQKESEIERVKL-IEELNV-KITESVSLN 1502
               +    K+     L+ +    A   + +   ++ +I  +K  I++L+  K  +   L 
Sbjct: 2164 SAANAEEMKDLIQRQLQDQSQSQAQQLNQQIKTRDDQITNLKQQIQQLSQSKQQQEQLLT 2223

Query: 1503 KQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFAS 1562
            +Q++ LN+ +  +    N++  +++  + +I   N  IT LQ  +++ +SK+Q   S  +
Sbjct: 2224 EQISVLNQQIRSKNESMNQLDESIKYFKSQIDQSNLTITQLQQEIQSLNSKLQ---SSKN 2280

Query: 1563 DTKQGRDEQLDNTMNKELLDAV 1584
            D  Q  +E  +     E++  +
Sbjct: 2281 DQNQINEENKELQNKIEIVQQI 2302



 Score =  161 bits (392), Expect = 1e-37
 Identities = 293/1469 (19%), Positives = 627/1469 (42%), Gaps = 131/1469 (8%)

Query: 143  DVTHLSNTIK-EKDNALSVLQVKMKIMETTILDLQEKINEKDQII--EAKNKATTXXXXX 199
            D+  L N I  +KD  L  L+ +++  +   +  Q+ +N+  QI   E KNK        
Sbjct: 1315 DLVQLKNMILIQKDEELEELRQQLQQSQEDFIK-QQNLNDSLQIHSRELKNKFDEYIETK 1373

Query: 200  XXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKL 259
                        + T+Q++ ++QE  +   AE     Q L  DI+ KD+    L+     
Sbjct: 1374 FSEEKRLNNEL-DLTEQKINELQEQ-VDQHAE---TIQNLQGDIQRKDLEYLQLQSQ--- 1425

Query: 260  LEAARFEISLEHSKLAQEL-EQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEI 318
            L+    + +LE S L  ++ E+              ++  + +   E K +IEE  ++ I
Sbjct: 1426 LQTKIQQHTLELSDLGGKMNEEQLKHQIEINQKQQEISDLNFQIQ-EGKEKIEELSNIII 1484

Query: 319  ANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNT 378
               T +    E +E    Q++Q + +++    ++  E   + + +K+     S K  ++T
Sbjct: 1485 DKETMIKSLEETIEGNTNQVQQQSIKIQEHQKSI--EGLTLENQNKQKQLEQSAKIIKDT 1542

Query: 379  ASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDK-EYVISEKDTXXXX 437
              +++   +QL+      D  +K N+ E + L++  Q  NK L +     +   +T    
Sbjct: 1543 QIELEELTTQLT------DQIEKFNQIEGSYLKL--QQQNKSLEELYNNTLKLLETKEED 1594

Query: 438  XXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVN 497
                   K+  IA + L  ++  +     +         ++ K  + + Q+ + EI  +N
Sbjct: 1595 LTTTVIQKNEEIASIHLSLEKLKQESEKEYKQLEDYSYEQLLKKMDDIAQK-DWEIDQLN 1653

Query: 498  --VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNK 555
              V+DL +KL++  E + Q + E D    N IK     K K+KQ  K I   +++ +  K
Sbjct: 1654 QVVQDLNQKLQAGMECVEQYDKEFD----NQIKEIDELKSKIKQKDKEIKECNEIIEKQK 1709

Query: 556  -EIVRLTEELHHLSQKVAE-LEEEKGNLQLHLVDYDSGRMIESDVYKKMIEME-NLAETR 612
             EI  + ++++   Q V + L+E + N  L L    +   I +    +++ ++  +AE +
Sbjct: 1710 LEIEAVNKQMNEELQLVTQSLQENQSNYDLEL---QAKLAILNKKEAQILNLDFQIAEFQ 1766

Query: 613  LKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSV-HLEEQIDAL 671
             + ++  + Q  +LVQE ++L ++   +ED+     +    Q+ S  +S+   EE  + L
Sbjct: 1767 -QNLNQQKDQIEELVQERNVLIERQKLIEDEKNQSDKEFKQQIQSLKESLSEFEENYNYL 1825

Query: 672  SASKKELALVIENLKLDKEQLYGTIKD-LENDKEDIMNKLQNYIQENMDLTD----KLEK 726
                +E    ++N    +++LY  ++   E D+E     +Q+ +Q   D  +    K  K
Sbjct: 1826 KQQHEE----VQNQFASQKELYNDLQQKYEEDQESSQQLIQD-LQSQKDKQNIEFQKYIK 1880

Query: 727  MSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIA 786
             S   I +   KIN +E+   Q Q  I+  +Q       N+E +  ++  +  RL E   
Sbjct: 1881 ESDLNIQKANNKINQKEEKIAQQQHLIET-LQS------NLEDKNQQHDEQGQRLFEKQN 1933

Query: 787  VMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEH 846
             +       +    +L   +QE     + Y ++  +L ++L  L +     EK  L  + 
Sbjct: 1934 ELNQVILEKQTNEKKLSQQIQECNNKIASYNLEVAQL-SQLITLKES----EKSQLSKQF 1988

Query: 847  ENKELQKKNQILLEEN--QNLQISLSDMQQHYNALVEKANRTDLA----ESESTKYQTQL 900
            E    Q K Q+  +    Q LQ  +++ Q++ +   +K N  +L     E E +    ++
Sbjct: 1989 EQTSDQLKQQLFQQTQFIQELQDYINESQENESKAGQKINTLNLQISTLEFEISNLNCEI 2048

Query: 901  RDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQL 960
              L++ +K+   E   L    +++I    I+   Q+++AI   ++L  + +K        
Sbjct: 2049 LKLQNTIKQSKEEKLRLEEDHQQDI----IQIQQQLQAAISANQLLKNEAQKK------- 2097

Query: 961  EAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQ 1020
              Q+  ++N  +NLN  +E+     ++++ + +Q+ Q +     ++  + +N  N ++  
Sbjct: 2098 --QINLFENE-QNLNSKIEQ-QVYEIKILKEEIQRLQLEMQRQVKESDSNLNNKNEMIDL 2153

Query: 1021 KDEEIIALNQKINNAQ----VSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQ 1076
              +++I +     NA+    +    +    +S+  Q   +++  ++++  + +Q+    Q
Sbjct: 2154 LKKQLIDIQNSAANAEEMKDLIQRQLQDQSQSQAQQLNQQIKTRDDQITNLKQQIQQLSQ 2213

Query: 1077 HNEELQILVREQ----DDQIKELKETKLTFEMNIPKTEGMIISS--TIEPMSDDANNVDX 1130
              ++ + L+ EQ    + QI+   E+    + +I   +  I  S  TI  +  +  +++ 
Sbjct: 2214 SKQQQEQLLTEQISVLNQQIRSKNESMNQLDESIKYFKSQIDQSNLTITQLQQEIQSLNS 2273

Query: 1131 XXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDV 1190
                       +  +E +E   +  ++Q+ S    +EL++   +I++LE           
Sbjct: 2274 KLQSSKNDQNQIN-EENKELQNKIEIVQQISNTAQSELEKLKQQILKLEEEKQR------ 2326

Query: 1191 VNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREAD- 1249
               EQI QL S++   N++N  +   +   +      +D +   I E ++QH  Q E   
Sbjct: 2327 -QSEQIKQLSSQINDQNSQNLQITQKLLSQKEE-KELIDLQQKNIQEQYQQHREQSEKQI 2384

Query: 1250 FQKTEHELRVQLSAFESKYEQLLDSVQSSTQEET-NKIVTMEQVTSLQNKLQDKEEHLRN 1308
            +Q T +  +++ +  E +   LL + Q S  EE  NK+   +Q+ ++ ++L D  +   +
Sbjct: 2385 YQLTNNVSQLEQTLSEIQNNLLLVNKQKSESEEKLNKLG--QQLQNVNSQLSDSRDKYES 2442

Query: 1309 LQEKYADVINQIEILRSEIED------EKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQM 1362
              ++    IN +    SE++       E+++                  L ++ Q    +
Sbjct: 2443 ENQQQLQQINNLSQENSELQQTLNEKLEELSKLQLDNTKLVQNQKKVDKLESQVQELSAL 2502

Query: 1363 QEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDS---EIYQK 1419
            +EQ+   I ++  +LK               + N   +   ++      KD    EI Q 
Sbjct: 2503 KEQNGKQIEQQELRLKSQQQELEQLRENYNLQKNQLNSLNQQIAQYEIDKDKLSKEIKQL 2562

Query: 1420 THEYTITLTQRNDEFENVRQQLVEYEKR--------IEDLTYEK-ESELAILRLKMHENA 1470
              +    L+Q     + + QQ  E EK         I D   ++ E+EL IL++K+ +  
Sbjct: 2563 QSQNQNYLSQVQKYQDYINQQQQELEKNTISNRSIVINDAQGQQLEAELKILQVKLVQQL 2622

Query: 1471 NHYETM--QKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALEN 1528
            N+Y+ +   K+++  + K+ E+L+    + V   +++    + + E++ K N      +N
Sbjct: 2623 NNYKQLIQDKKNQEIKAKINEDLDQIKKDYVMALEKIGIFIRGI-EDLEKVN----GPKN 2677

Query: 1529 QEIEIVTLNDEITNLQNMVRASSSKIQKH 1557
            Q+  +      I  + +  +    K+ KH
Sbjct: 2678 QQYHVFNFQKRIKQINSRTQRFYFKVCKH 2706



 Score =  155 bits (376), Expect = 1e-35
 Identities = 262/1429 (18%), Positives = 633/1429 (44%), Gaps = 122/1429 (8%)

Query: 221  MQENFIAMEAEWKDEKQRLLK---DIESKDVRISSLEEANKLLE-AARFEISLEH-SKLA 275
            ++EN I +E    + +++LL+   +I+ K+ +I  L++  +L +  A+ E  LE+  +  
Sbjct: 1051 LKENQIQIEDIHSNHQKQLLQKQNEIQDKEYQIKKLDQ--QLFDYQAQMEQRLEYIQQKE 1108

Query: 276  QELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLN 335
            QE+E+                ++ I+     +    E    +  +  E  K+ +++  L 
Sbjct: 1109 QEVEKLSQHNDVLENDAQQKEQEIIQLKNHSQNLSVELEKFKQYSQLEQEKQQQVILELT 1168

Query: 336  CQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLN 395
              ++Q+ +  + +  +M  + K++       +  I +   +++ +++   + +L +E   
Sbjct: 1169 ENLKQSEQLFKQQNKSMEDQIKSLEQQITNQNQKIVQL--QDSINQLNQKYQELKNE--- 1223

Query: 396  QDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLE 455
                K++ + E  K    +Q  N+  +  E + S+  T           +    +QL  E
Sbjct: 1224 ----KQLKEAEYEKQLQELQ--NQSDIQNEAIDSQIQTNVEQSDQISKLEQNK-SQLLEE 1276

Query: 456  HQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKD-VNVKDLIEKLKSAEEQITQ 514
             Q  +E    + + T  + + ++  VQ+Q   E+N + +D V +K++I  L   +E++ +
Sbjct: 1277 LQNVVEEKKQVEL-TYKQAIEDLKTVQDQRIAEINKKNQDLVQLKNMI--LIQKDEELEE 1333

Query: 515  LNDEIDAANKNMIKVKS-NHKLKL--KQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKV 571
            L  ++  + ++ IK ++ N  L++  ++++   D + +   S ++  RL  EL    QK+
Sbjct: 1334 LRQQLQQSQEDFIKQQNLNDSLQIHSRELKNKFDEYIETKFSEEK--RLNNELDLTEQKI 1391

Query: 572  AELEEE-----------KGNLQLHLVDY-DSGRMIESDVYKKMIEMENLA----ETRLK- 614
             EL+E+           +G++Q   ++Y      +++ + +  +E+ +L     E +LK 
Sbjct: 1392 NELQEQVDQHAETIQNLQGDIQRKDLEYLQLQSQLQTKIQQHTLELSDLGGKMNEEQLKH 1451

Query: 615  --AISLLESQKFDLVQELHILQQKYDEVEDKLADI-SQLQSDQVCSEIKSVHLEEQIDAL 671
               I+  + +  DL  ++   ++K +E+ + + D  + ++S +   E  +  +++Q   +
Sbjct: 1452 QIEINQKQQEISDLNFQIQEGKEKIEELSNIIIDKETMIKSLEETIEGNTNQVQQQSIKI 1511

Query: 672  SASKKEL-ALVIENLKLDK--EQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMS 728
               +K +  L +EN    K  EQ    IKD + + E++  +L + I++   +     K+ 
Sbjct: 1512 QEHQKSIEGLTLENQNKQKQLEQSAKIIKDTQIELEELTTQLTDQIEKFNQIEGSYLKLQ 1571

Query: 729  AEK--ISEL----LAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSK-YKS----- 776
             +   + EL    L  +  +E+    T    + +I    L +E ++ E  K YK      
Sbjct: 1572 QQNKSLEELYNNTLKLLETKEEDLTTTVIQKNEEIASIHLSLEKLKQESEKEYKQLEDYS 1631

Query: 777  --RICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYT------IQE-DELVNRL 827
              ++ +  + IA  +     L +    L   LQ   +   +Y       I+E DEL +++
Sbjct: 1632 YEQLLKKMDDIAQKDWEIDQLNQVVQDLNQKLQAGMECVEQYDKEFDNQIKEIDELKSKI 1691

Query: 828  AV----LMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKA 883
                  + + + ++EKQ LEIE  NK++ ++ Q++ +  Q  Q +     Q   A++ K 
Sbjct: 1692 KQKDKEIKECNEIIEKQKLEIEAVNKQMNEELQLVTQSLQENQSNYDLELQAKLAILNKK 1751

Query: 884  NRTDL-AESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRD 942
                L  + +  ++Q  L   +  ++ +  E   LI +++K IED + + + + +  I+ 
Sbjct: 1752 EAQILNLDFQIAEFQQNLNQQKDQIEELVQERNVLI-ERQKLIEDEKNQSDKEFKQQIQS 1810

Query: 943  KKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPD 1002
             K    ++E+N  Y+ Q   ++Q    + + L  ++++  + + E   + +Q  Q+Q   
Sbjct: 1811 LKESLSEFEENYNYLKQQHEEVQNQFASQKELYNDLQQKYEEDQESSQQLIQDLQSQKDK 1870

Query: 1003 YTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEE 1062
               ++   I + +  +++ + +I    +KI   Q    ++ S+ E K  Q   + + + E
Sbjct: 1871 QNIEFQKYIKESDLNIQKANNKINQKEEKIAQQQHLIETLQSNLEDKNQQHDEQGQRLFE 1930

Query: 1063 EMQRVSKQLLDSKQHNEELQILVREQDDQIK--ELKETKLTFEMNIPKTEGMIISSTIEP 1120
            +   +++ +L+ + + ++L   ++E +++I    L+  +L+  + + ++E   +S   E 
Sbjct: 1931 KQNELNQVILEKQTNEKKLSQQIQECNNKIASYNLEVAQLSQLITLKESEKSQLSKQFEQ 1990

Query: 1121 MSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLET 1180
             SD                    +QE +++I E    QE  +K     Q+  T  +Q+ T
Sbjct: 1991 TSDQLKQ--------QLFQQTQFIQELQDYINES---QENESKAG---QKINTLNLQIST 2036

Query: 1181 LNTELTGHDVVNQEQINQLK-SKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELW 1239
            L  E++  +    +  N +K SK E+L  E D+    + +++  + +A+        +L 
Sbjct: 2037 LEFEISNLNCEILKLQNTIKQSKEEKLRLEEDH-QQDIIQIQQQLQAAISAN-----QLL 2090

Query: 1240 KQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKL 1299
            K    +++ +  + E  L  ++     + + L + +Q    E   ++   +   + +N++
Sbjct: 2091 KNEAQKKQINLFENEQNLNSKIEQQVYEIKILKEEIQRLQLEMQRQVKESDSNLNNKNEM 2150

Query: 1300 QD-KEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQS 1358
             D  ++ L ++Q   A+     ++++ +++D+  +                 +L+ + Q 
Sbjct: 2151 IDLLKKQLIDIQNSAANAEEMKDLIQRQLQDQSQSQAQQLNQQIKTRDDQITNLKQQIQQ 2210

Query: 1359 Y---KQMQEQ----SILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLEL 1411
                KQ QEQ     I  +N++     +S             +++ +   + +L  +++ 
Sbjct: 2211 LSQSKQQQEQLLTEQISVLNQQIRSKNESMNQLDESIKYFKSQIDQSNLTITQLQQEIQS 2270

Query: 1412 KDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENAN 1471
             +S++    ++    + + N E +N + ++V+          EK  +  IL+L+  +   
Sbjct: 2271 LNSKLQSSKNDQN-QINEENKELQN-KIEIVQQISNTAQSELEKLKQ-QILKLEEEKQRQ 2327

Query: 1472 HYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEI 1531
              +  Q  S+I         N++IT+ +   K+  EL    ++ + +  + Q   E  E 
Sbjct: 2328 SEQIKQLSSQINDQ---NSQNLQITQKLLSQKEEKELIDLQQKNIQE--QYQQHREQSEK 2382

Query: 1532 EIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKEL 1580
            +I  L + ++ L+  +    S+IQ ++   +  K   +E+L N + ++L
Sbjct: 2383 QIYQLTNNVSQLEQTL----SEIQNNLLLVNKQKSESEEKL-NKLGQQL 2426



 Score =  113 bits (272), Expect = 4e-23
 Identities = 166/884 (18%), Positives = 386/884 (43%), Gaps = 82/884 (9%)

Query: 730  EKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVME 789
            E+ +++L+K+   E  +   Q   +  ++     IEN++ + +K   +I  L+E++ +M 
Sbjct: 55   EETNKVLSKLEVVENDEDSNQRSSET-VESLQKVIENLQKDCNKKDQKIQDLQENLVIMS 113

Query: 790  DRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRL----AVLMDHDRVVEKQLLEIE 845
            D+   ++ +  ++   +Q++ K  SE+  +  +L+  L      L +  +    +  +I+
Sbjct: 114  DQ---MKFRESKIREEVQQETKETSEFGNERVKLITELRKCQVDLQESQKQNANKFSQIQ 170

Query: 846  H-ENKELQKKNQILLE------ENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQT 898
               NK  Q +N   LE      +NQ L+  L   QQ  + L +K        S+      
Sbjct: 171  QLTNKATQIQNLSKLEIDKLKQQNQELEEKLLQSQQKVDQLAQKIEELKELNSQLNLQSQ 230

Query: 899  QLRD----LESNLKRITHEHQTLIVQKKKEIEDLEIE------FNTQIES-AIRDKKVLN 947
            ++ D    LE   ++   E +  I+  ++ IEDL+I+       N Q+ES AI     + 
Sbjct: 231  EVEDVKQKLEKEFQQRYDEVEFEIINNRQIIEDLQIQLKELKALNLQLESAAINGTFDMK 290

Query: 948  EKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDK------HVQKQQTQSP 1001
            ++     +   +L+ Q QE +  +    +  +++NK     I+K       +Q++  Q+ 
Sbjct: 291  QQISLLQDQTNELQNQNQELQQKLHAKQIEFDQMNKAKSREIEKLKQDKIELQQELEQTK 350

Query: 1002 DYTEQ--------YINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQF 1053
              +EQ        Y N++  L    ++ +E+   LNQKI       +     Y++  +Q 
Sbjct: 351  QISEQTQAETESNYKNQMLILQDKFQKSEEQTSKLNQKIQELSADLIQERMLYKNNESQL 410

Query: 1054 TTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMI 1113
               +   ++E+ + S  +L   Q  E+++IL   QD  +++  ET ++   NI   + ++
Sbjct: 411  NGVITQQKDELSQKSSLVL---QLTEKIRIL---QDHSMQQ--ETNIS--KNIDDYKVLL 460

Query: 1114 ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQE-CY 1172
                      D NN              LK Q+ ++  + + V+ +   ++   L E   
Sbjct: 461  ----------DQNN--QQITQLSEQIKSLKKQQRQQEQENKQVISQYEQQIKQYLAEITQ 508

Query: 1173 TKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRG 1232
            TKI + E+ N        ++Q  I + K +L+Q N    +L + + + + +I    +QR 
Sbjct: 509  TKIQKNESDNQRQNSESQLSQ-IIEKQKVQLQQANAIIQDLNNQIEQFQQNIQDQEEQR- 566

Query: 1233 FEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQV 1292
              +  + +  L ++E+     E ++    +    K +Q++   Q   +++++  + + + 
Sbjct: 567  MSVISVKQSLLIEKESQINMLESQVIKYQNELTQKQDQIIILQQQYEKQKSDFNLAISE- 625

Query: 1293 TSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDL 1352
               +N     ++H + LQ K +D+  ++  LRS ++  +V                   L
Sbjct: 626  -KEKNAKLTNQQH-QELQNKVSDLTFEVNQLRSLVDKAEVDKESNIQQYNEANQQLKDQL 683

Query: 1353 RTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELK 1412
             T+N   +++QE    + ++E   L+KS+             +N  + ++ +L + L  +
Sbjct: 684  NTQNSLIQELQEYLKESNSKEQLALQKST--------QQSLEINQLQLEIGKLKNDLSQQ 735

Query: 1413 DSEIYQKTHEYTITLTQ---RNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHEN 1469
            + +  Q   E +  L +   +N+  +N  +Q+   + +++   ++   ++  L++K+ E+
Sbjct: 736  EQKQSQTNLENSYKLKEQQTQNETLKNDFKQIQLVQDKLKQENFQLNEQINDLQIKLQES 795

Query: 1470 ANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQ 1529
              + +   + +E ++ +L ++LN ++ +     + V +  K   +++ + ++ Q    ++
Sbjct: 796  QENLKQTTQINENQKEQL-QKLNDQLYQE-QQKESVNQTEKFYLQQLIQQHKDQVNEVHE 853

Query: 1530 EIEIVTLNDEITNLQ-NMVRASSSKIQKHVSFASDTKQGRDEQL 1572
            + +++T   E  + Q   ++      QKH      T+     QL
Sbjct: 854  KNKLITSISESKDKQIEALKKQGEDAQKHYEQQKQTQYEEMVQL 897



 Score = 58.4 bits (135), Expect = 2e-06
 Identities = 115/656 (17%), Positives = 272/656 (41%), Gaps = 69/656 (10%)

Query: 980  ELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSY 1039
            E N+++++ +    Q     +P   +Q      K   + +   +++   N +  N  +S 
Sbjct: 7    EANRLSVKQLAGRFQSMMKAAPVQQQQQPPP-RKSEVIARNPQQQL--QNMEETNKVLSK 63

Query: 1040 MSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETK 1099
            + +V + E    + +  +E++++ ++ + K      Q  ++LQ  +    DQ+K  +E+K
Sbjct: 64   LEVVENDEDSNQRSSETVESLQKVIENLQKDCNKKDQKIQDLQENLVIMSDQMK-FRESK 122

Query: 1100 LTFEMNIPKTEGMIISSTIEPMSDDAN--NVDXXXXXXXXXXXXLKVQE-EEEFIQERSV 1156
            +  E+     E     +    +  +     VD             ++Q+   +  Q +++
Sbjct: 123  IREEVQQETKETSEFGNERVKLITELRKCQVDLQESQKQNANKFSQIQQLTNKATQIQNL 182

Query: 1157 LQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLST 1216
             + +  KL  + QE   K++Q +    +L        ++I +LK    QLN ++  +   
Sbjct: 183  SKLEIDKLKQQNQELEEKLLQSQQKVDQLA-------QKIEELKELNSQLNLQSQEVEDV 235

Query: 1217 VAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEH-ELRVQLSAFESKYEQLLDSV 1275
              +L        D+  FEI    +Q +   +   ++ +   L+++ +A    ++  +   
Sbjct: 236  KQKLEKEFQQRYDEVEFEIINN-RQIIEDLQIQLKELKALNLQLESAAINGTFD--MKQQ 292

Query: 1276 QSSTQEETNKIVTMEQVTSLQNKLQDKE---EHLRNLQEKYADVINQIEI-LRSEIEDEK 1331
             S  Q++TN++    Q   LQ KL  K+   + +   + +  + + Q +I L+ E+E  K
Sbjct: 293  ISLLQDQTNELQNQNQ--ELQQKLHAKQIEFDQMNKAKSREIEKLKQDKIELQQELEQTK 350

Query: 1332 VAFXXXXXXXXXXXXXXXXDL-----RTENQSYKQMQEQSILNIN--EENAQLKKSSXXX 1384
                                L     ++E Q+ K  Q+   L+ +  +E    K +    
Sbjct: 351  QISEQTQAETESNYKNQMLILQDKFQKSEEQTSKLNQKIQELSADLIQERMLYKNNESQL 410

Query: 1385 XXXXXXXXXRVNDAEAKVLELTHQLE-LKDSEIYQKTH------EYTITLTQRNDEFENV 1437
                      ++   + VL+LT ++  L+D  + Q+T+      +Y + L Q N +   +
Sbjct: 411  NGVITQQKDELSQKSSLVLQLTEKIRILQDHSMQQETNISKNIDDYKVLLDQNNQQITQL 470

Query: 1438 RQQLVEYEKRIEDLTYEKESELA------------ILRLKMHENANHYETMQKESEIERV 1485
             +Q+   +K+      E +  ++            I + K+ +N +  +    ES++ ++
Sbjct: 471  SEQIKSLKKQQRQQEQENKQVISQYEQQIKQYLAEITQTKIQKNESDNQRQNSESQLSQI 530

Query: 1486 KLIEELNVKITES----VSLNKQVAELNKAL----EEEVAKTNEMQTALENQEIEIVTLN 1537
              IE+  V++ ++      LN Q+ +  + +    E+ ++  +  Q+ L  +E +I  L 
Sbjct: 531  --IEKQKVQLQQANAIIQDLNNQIEQFQQNIQDQEEQRMSVISVKQSLLIEKESQINMLE 588

Query: 1538 DEITNLQNMVRASSSKI----QKHVSFASD-----TKQGRDEQLDNTMNKELLDAV 1584
             ++   QN +     +I    Q++    SD     +++ ++ +L N  ++EL + V
Sbjct: 589  SQVIKYQNELTQKQDQIIILQQQYEKQKSDFNLAISEKEKNAKLTNQQHQELQNKV 644


>UniRef50_A2E8H6 Cluster: Viral A-type inclusion protein, putative;
            n=1; Trichomonas vaginalis G3|Rep: Viral A-type inclusion
            protein, putative - Trichomonas vaginalis G3
          Length = 2458

 Score =  188 bits (458), Expect = 1e-45
 Identities = 313/1486 (21%), Positives = 651/1486 (43%), Gaps = 118/1486 (7%)

Query: 154  KDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXED 213
            ++N    L+ + + ++  I +L+E++N+K+   + +N                      +
Sbjct: 660  EENESEELKSENENLKKQIEELKEQLNQKEDQGQEENGWCNENETEDLKSEIEQLKKENE 719

Query: 214  TKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEIS-LEHS 272
            T +Q  + +    +++ + ++ K++L K  E +    +   E N+  E  + +IS LE+ 
Sbjct: 720  TLKQNNETE----SLKKQIEELKEQL-KQKEDQGQEENGWGEENET-EDYKSQISALENE 773

Query: 273  K--LAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIEL 330
            K  L ++++               L +Q  E +     +  +  S+E  N TE  +KI  
Sbjct: 774  KRTLNKKIKDLANGLKTLKSKNEKLEQQLKENANNGNNDNSKDISVEF-NETE--EKITE 830

Query: 331  LEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLIS--RKSGRNTASKMKSPWSQ 388
            LE  N ++R+ N+ L  +  T+  ++  + S +K  S  +S  R+       +  S  ++
Sbjct: 831  LEFENEELRRNNESLSEEKKTLHKQNNKLVSENKTLSDEVSTLREQVEELEEETISTSNE 890

Query: 389  LSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTL 448
            L SE  +  ++  + + E+ + +    ++N +  +   V S++              + L
Sbjct: 891  LRSEIEHLRSELVVREQELEQTKNNNNNVNNNENNNSNVHSDQSIYEEKISLLKQQLEEL 950

Query: 449  I-AQLQLEHQQHMEGPSLIHVGTNTEDVN-EIAKVQEQLKQ--ELNDEIKDVNVKDLIEK 504
              +Q    + + +E  + I +    ED+  E   +Q QL +  E N+   +   +D I K
Sbjct: 951  KQSQSSNNNNEELEKEN-ISLKKEIEDLKQENEGLQNQLFEGGETNEN-NNQEKEDEIHK 1008

Query: 505  LKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQ-KTIDNF-SKVSDSNKEIVRLTE 562
            LKS   +I +L  +++++ +N  K + N+    +  + + IDN  S++ + NK++    +
Sbjct: 1009 LKS---EIEELKKKLESSEQN--KEEENNGWGDENTETENIDNLKSEIEELNKKLDESIK 1063

Query: 563  ELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIE--MENLAETRLKAISLLE 620
                  +K+ E+++E   LQ  L + +S   I    +K  +E   + L E+  K   L +
Sbjct: 1064 SNDEKQKKIEEMKQENEELQTQLFENNSEEEINK--FKSQVEELTQKLQESNQKNEEL-Q 1120

Query: 621  SQKFDLVQELHILQQKYDEVEDKLA-DISQLQSDQVCSEIKSVHLEEQIDALSASKKELA 679
            SQ      E+  L+++ +E  +KL  +IS L++     EI  +  +E+ +     K+   
Sbjct: 1121 SQTEKQNNEIDDLKKQKEEENEKLQKEISDLKN-----EISQLQQKEEENGSDLQKQIEV 1175

Query: 680  LVIENLKLDK--EQLYGTIKDLENDKE---DIMNKLQNYIQENMDLTDKLEKMSAEKISE 734
            L   N K D+  EQL   I +L+ +KE   + +N L++ +Q   ++  + EK   E I +
Sbjct: 1176 LKQTNEKNDEDIEQLAKQIDELQTEKEKQNEEINDLKSQLQNVSEIKSENEKQKNE-IDD 1234

Query: 735  LLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRI-----CRLEESIAVME 789
            L      +E  ++QTQ       QE++  I  ++SE+ + K ++      + EE+I  ++
Sbjct: 1235 L-----KKENEELQTQLFEIGNNQEKEEEIHKLKSEIEELKKKLEESEQNKEEENIDNLK 1289

Query: 790  DRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENK 849
                +L+ +  +L S  ++ +K  SE   QE++ +++        +  E+     E+E++
Sbjct: 1290 SENETLKEEIKRLESDNEQLKKQNSELQ-QENKSLHQ-----QQSKEEEENGWGEENESE 1343

Query: 850  ELQKKNQILLEENQNLQISLS---DMQQHYNALVEKANRTDLAESESTKYQTQLRDLESN 906
            EL+ +N+ L ++ + L+  L    D  Q  N   ++ N T+  +S+ +  + + R L   
Sbjct: 1344 ELKSENESLKKQIEELKEQLKQKEDQGQEENGWGDE-NETEDYKSQISALENEKRTLNKK 1402

Query: 907  LKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQE 966
            +K + +  +TL   K +++E    + N+   S   + K ++ ++ +  E +T+LE + +E
Sbjct: 1403 IKDLANGLKTL-KSKNEKLEQQLKDINSN-NSTNDNSKDISVEFNETEEKITELEFENEE 1460

Query: 967  YKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEII 1026
             + N E+L+   + L K N    +K V + +T S        +E++ L   +++ +EE I
Sbjct: 1461 LRRNNESLSEEKKTLQKQN----NKLVSENKTLS--------DEVSTLREQVEELEEETI 1508

Query: 1027 ALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVR 1086
            + + ++ +      S +   E +L Q      N+       S    D   + E++ +L +
Sbjct: 1509 STSNELRSEIEHLRSELVLREQELEQTKNNNNNVNNNENNNSNVHSDQSIYEEKISLL-K 1567

Query: 1087 EQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQE 1146
            +Q +++K+ ++     E N    E   +   IE +  +   +                ++
Sbjct: 1568 QQLEELKQQQQKPFDHEDNNDSDEINKLKKEIEDLKQENEELQNQLFEGGETNENNNQEK 1627

Query: 1147 EEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQL 1206
            E+E  + +S ++E   KL +  Q    +       NTE    + +  E I +L  KL +L
Sbjct: 1628 EDEIHKLKSEIEELKKKLESSEQNKEEENNGWGDENTETENIENLKSE-IEELNKKLNEL 1686

Query: 1207 NTENDNLLSTVAELRSSISSAVDQRGFEIAEL--WKQHLAQREADF-------QKTEHEL 1257
            +  ND     + EL   +  + + +  E   +   K+ L Q   D        Q+    L
Sbjct: 1687 SKSNDEKQKKIEELEQKLQESQNNKDEEEENIEDLKEQLEQLRRDAITKSKQDQEEIENL 1746

Query: 1258 RVQLSAFESKYEQLLDSVQSSTQEETNKIVT-MEQVTSLQNKLQDKEEHLRNLQEKYADV 1316
            + Q+   E+  E++ + ++   ++   K     E++  LQN++Q ++E + NL  +  D 
Sbjct: 1747 KKQIEEKEADIEEITEELEQLRKDSITKAKQDQEEIEKLQNEIQKQKEIIDNLNAEI-DE 1805

Query: 1317 INQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQ 1376
            + + E    +++DE                     L  E  + K   E    NI  ++  
Sbjct: 1806 LGEKEAEHEDLKDELQQLRKDSLQKAKIDQAEIDRLNAEVSNLKFELENGKENIWGDDDD 1865

Query: 1377 LKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQL-ELKD-SEIYQKTHEYTITLTQR---- 1430
             +K               + D  +++ +L  ++ + +D +E+ Q+  +    L Q     
Sbjct: 1866 NEKHKETLTEIIEKLKSEIEDKNSEIEKLEEEISQFEDPTEVKQENKKLKEELDQALRQN 1925

Query: 1431 ------NDEFENVRQQLVEYEKRIEDLTYEKE-SELAILRLKMHENAN--HYETMQKESE 1481
                  N+E   +R+QL +     E  T EK+  E      K+H++ N   +E     + 
Sbjct: 1926 AELGNVNEENNKLREQLKQSIDTNELKTLEKKLKEKEEENQKLHDDLNTLQFELNNSIAG 1985

Query: 1482 IERVKLIEELNVK--ITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDE 1539
            + ++   E + ++  +    + NK+++EL K LEEE    N + + LEN    +V  ND 
Sbjct: 1986 LPKINQSESMEIRDEVERLANENKKLSELTKKLEEE---KNFLVSQLEN----VVQRNDY 2038

Query: 1540 ITNLQNMVRASSSKIQKHVSFASDTKQGRDE--QLDNTMNKELLDA 1583
               LQN V     K++K      +  Q  DE  + + T N E  DA
Sbjct: 2039 EKELQN-VEELKLKLKKAEKDNEELLQQIDELVEQNETENHEKSDA 2083



 Score =  176 bits (429), Expect = 4e-42
 Identities = 311/1489 (20%), Positives = 627/1489 (42%), Gaps = 141/1489 (9%)

Query: 153  EKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXE 212
            +KD +       +  ++  ++ L+++I +KDQ I   N   T                 E
Sbjct: 265  QKDASSDDKNSDLSRLKKAVVQLKKQIAQKDQEI---NDLKTSNMQLQNFNNETQNVEIE 321

Query: 213  DTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLE--AARFEISLE 270
              K Q+ + Q+   +++AE    +      ++     I  L++ N  L+      E    
Sbjct: 322  KYKSQIIEFQKIIESLKAENAKLQTENTNTVDKLQSEIEKLKQENSELQNQIQENEDGWN 381

Query: 271  HSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIEL 330
             +   +EL+                 K+S     E+  +I +  S +I ++ +   + + 
Sbjct: 382  DNNNEEELQNQITELQKQLEEN----KKSYSEETEQLKQIIDDDSKQIEDLKQKLAEAQD 437

Query: 331  LE-HLNCQIR--QTNKE-LENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPW 386
             E + + Q+   QT K+ L+ KL  +    + + + +      IS+ +  N  S ++   
Sbjct: 438  HEGNSDSQLAKLQTEKQQLDKKLVDVANALRKLKTKNDNDQATISKLNEEN--SSLQKQI 495

Query: 387  SQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKD 446
             +L  +T N  + +     EI  L+  +Q L    +  + + +E +            ++
Sbjct: 496  EELKQQTANNASYEA----EIQNLKKQLQDLQ---IQNDDIKTENEHLQQEMFENNKSEE 548

Query: 447  TLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLK---QELNDEIKDVNVKDLI- 502
                + Q+   Q         +    +++  + K  EQ+K   QELN+E+   N  +   
Sbjct: 549  IEQQKKQISELQKEISSKSSEIQAKNDEIENLNKEIEQIKKENQELNEELFQNNENNSND 608

Query: 503  EKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSN-----KEI 557
            E+++  + QI  L  EI     ++ +  +N+K +++++++ ++      D N      E 
Sbjct: 609  EEIEKLKTQIQSLQKEIS----DLSQQNNNYKSQVEELKEELEKHQSEQDENGWGEENES 664

Query: 558  VRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETR--LKA 615
              L  E  +L +++ EL+E+  N +      ++G   E++      E+E L +    LK 
Sbjct: 665  EELKSENENLKKQIEELKEQL-NQKEDQGQEENGWCNENETEDLKSEIEQLKKENETLKQ 723

Query: 616  ISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASK 675
             +  ES K  + +    L+QK D+ +++     + +++   S+I +  LE +   L+   
Sbjct: 724  NNETESLKKQIEELKEQLKQKEDQGQEENGWGEENETEDYKSQISA--LENEKRTLNKKI 781

Query: 676  KELALVIENLKLDKEQLYGTIKDLEND-----KEDI---MNKLQNYIQE----NMDLTDK 723
            K+LA  ++ LK   E+L   +K+  N+      +DI    N+ +  I E    N +L   
Sbjct: 782  KDLANGLKTLKSKNEKLEQQLKENANNGNNDNSKDISVEFNETEEKITELEFENEELRRN 841

Query: 724  LEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESEL----SKYKSRIC 779
             E +S EK  + L K N++  S+ +T     + ++E+   +E +E E     ++ +S I 
Sbjct: 842  NESLSEEK--KTLHKQNNKLVSENKTLSDEVSTLREQ---VEELEEETISTSNELRSEIE 896

Query: 780  RLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDE--LVNRLAVLMDHDRVV 837
             L   + V E      +   + + +        +S+ +I E++  L+ +    +   +  
Sbjct: 897  HLRSELVVREQELEQTKNNNNNVNNNENNNSNVHSDQSIYEEKISLLKQQLEELKQSQSS 956

Query: 838  EKQLLEIEHENKELQKKNQILLEENQNLQISLSDM-QQHYNALVEKANRTDLAESESTKY 896
                 E+E EN  L+K+ + L +EN+ LQ  L +  + + N   EK +     +SE  + 
Sbjct: 957  NNNNEELEKENISLKKEIEDLKQENEGLQNQLFEGGETNENNNQEKEDEIHKLKSEIEEL 1016

Query: 897  QTQLRDLESNLKRITH---EHQTL---IVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKY 950
            + +L   E N +   +   +  T    I   K EIE+L  + +  I+S    +K + E  
Sbjct: 1017 KKKLESSEQNKEEENNGWGDENTETENIDNLKSEIEELNKKLDESIKSNDEKQKKIEEMK 1076

Query: 951  EKNIEYVTQL-----EAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTE 1005
            ++N E  TQL     E ++ ++K+ +E L   ++E N+ N EL        Q+Q    TE
Sbjct: 1077 QENEELQTQLFENNSEEEINKFKSQVEELTQKLQESNQKNEEL--------QSQ----TE 1124

Query: 1006 QYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQ 1065
            +  NEI+ L    KQK+EE    N+K+          +SD +++++Q   K E    ++Q
Sbjct: 1125 KQNNEIDDLK---KQKEEE----NEKLQKE-------ISDLKNEISQLQQKEEENGSDLQ 1170

Query: 1066 RVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDA 1125
            +  + L  + + N+E    + +Q D+++  KE K   E+N  K++   +S          
Sbjct: 1171 KQIEVLKQTNEKNDEDIEQLAKQIDELQTEKE-KQNEEINDLKSQLQNVSEIKSENEKQK 1229

Query: 1126 NNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTEL 1185
            N +D            L+ Q  E  I      +E+  KL +E++E   K+ + E  N E 
Sbjct: 1230 NEIDDLKKENEE----LQTQLFE--IGNNQEKEEEIHKLKSEIEELKKKLEESEQ-NKEE 1282

Query: 1186 TGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAEL-WKQHLA 1244
               D +  E    LK ++++L ++N+ L    +EL+    S   Q+  E  E  W +   
Sbjct: 1283 ENIDNLKSEN-ETLKEEIKRLESDNEQLKKQNSELQQENKSLHQQQSKEEEENGWGE--- 1338

Query: 1245 QREADFQKTEHE-LRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKE 1303
            + E++  K+E+E L+ Q+   + + +Q  D  Q     E N      +    ++++   E
Sbjct: 1339 ENESEELKSENESLKKQIEELKEQLKQKEDQGQ-----EENGWGDENETEDYKSQISALE 1393

Query: 1304 EHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQ 1363
               R L +K  D+ N ++ L+S+  +EK+                  D+  E        
Sbjct: 1394 NEKRTLNKKIKDLANGLKTLKSK--NEKLEQQLKDINSNNSTNDNSKDISVEFNE----T 1447

Query: 1364 EQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEY 1423
            E+ I  +  EN +L++++            + N   ++   L+ ++     ++ +   E 
Sbjct: 1448 EEKITELEFENEELRRNNESLSEEKKTLQKQNNKLVSENKTLSDEVSTLREQVEELEEET 1507

Query: 1424 TITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENAN-HYETMQKESEI 1482
              T  +   E E++R +LV  E+ +E       +    +    + N+N H +    E +I
Sbjct: 1508 ISTSNELRSEIEHLRSELVLREQELEQTKNNNNN----VNNNENNNSNVHSDQSIYEEKI 1563

Query: 1483 ERVKL-IEELNVKIT-----ESVSLNKQVAELNKALEEEVAKTNEMQTAL----ENQEIE 1532
              +K  +EEL  +       E  + + ++ +L K +E+   +  E+Q  L    E  E  
Sbjct: 1564 SLLKQQLEELKQQQQKPFDHEDNNDSDEINKLKKEIEDLKQENEELQNQLFEGGETNENN 1623

Query: 1533 IVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELL 1581
                 DEI  L++ +     K++       +   G  ++   T N E L
Sbjct: 1624 NQEKEDEIHKLKSEIEELKKKLESSEQNKEEENNGWGDENTETENIENL 1672



 Score =  169 bits (410), Expect = 7e-40
 Identities = 258/1233 (20%), Positives = 541/1233 (43%), Gaps = 104/1233 (8%)

Query: 405  NEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPS 464
            NE+A+ +  I+   K + D    I               G + ++ + + +  + +E  +
Sbjct: 66   NELAECDKKIEEKEKLIEDLAKEIENMKNTTSTASQNDSGLEEVVQEFE-QKIETLESEN 124

Query: 465  LIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVK--DLIEKLKSAEEQITQLNDEIDAA 522
                  N+E   +I + +E L  +L+ E  ++  K  ++  + KSAEE + Q   + D  
Sbjct: 125  KTMKDQNSELQQQIQQYKE-LTDKLSTESTELQQKMENIKSEDKSAEETLLQTISDQDIQ 183

Query: 523  NKNMIKVKSNHKLKLKQMQKTIDNFS-KVSDSNKEIVRLTEEL---HHLSQKVAELEEEK 578
               + +     KL     ++  + F+ K  + N +I  L  +L     LS ++A L+ + 
Sbjct: 184  INKLKEELEQAKLAANSSEQNTNAFAQKEQELNAQITDLKNQLAAKDSLSDEIASLKAQI 243

Query: 579  GNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYD 638
              L  +    +S    E++  K   + +  ++ +   +S L+     L +++    QK  
Sbjct: 244  AELNQN----NSKSSEENEQLKAESQKDASSDDKNSDLSRLKKAVVQLKKQI---AQKDQ 296

Query: 639  EVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKEL-ALVIENLKLDKEQLYGTIK 697
            E+ D      QLQ+    +E ++V +E+    +   +K + +L  EN KL  E    T+ 
Sbjct: 297  EINDLKTSNMQLQNFN--NETQNVEIEKYKSQIIEFQKIIESLKAENAKLQTENT-NTVD 353

Query: 698  DLENDKEDIM---NKLQNYIQENMD--LTDKLEKMSAEKISELLAKINHEEQSKIQTQFG 752
             L+++ E +    ++LQN IQEN D    +  E+    +I+EL  ++   ++S  +    
Sbjct: 354  KLQSEIEKLKQENSELQNQIQENEDGWNDNNNEEELQNQITELQKQLEENKKSYSEETEQ 413

Query: 753  IDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKA 812
            +   I +    IE+++ +L++ +      +  +A ++  +  L++K   + + L+ K K 
Sbjct: 414  LKQIIDDDSKQIEDLKQKLAEAQDHEGNSDSQLAKLQTEKQQLDKKLVDVANALR-KLKT 472

Query: 813  YSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHE---NKELQKKNQILLEENQNLQISL 869
             ++     D+    ++ L + +  ++KQ+ E++ +   N   + + Q L ++ Q+LQI  
Sbjct: 473  KND----NDQAT--ISKLNEENSSLQKQIEELKQQTANNASYEAEIQNLKKQLQDLQIQN 526

Query: 870  SDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDL- 928
             D++     L ++    + +E E  + + Q+ +L+  +   + E Q     K  EIE+L 
Sbjct: 527  DDIKTENEHLQQEMFENNKSE-EIEQQKKQISELQKEISSKSSEIQA----KNDEIENLN 581

Query: 929  -EIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENL---NMNVEELNKM 984
             EIE   +    + ++   N +   N E + +L+ Q+Q  +  I +L   N N +   + 
Sbjct: 582  KEIEQIKKENQELNEELFQNNENNSNDEEIEKLKTQIQSLQKEISDLSQQNNNYKSQVEE 641

Query: 985  NLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIA-LNQKINNAQVSYMSMV 1043
              E ++KH Q +Q ++    E    E+   N  LK++ EE+   LNQK +  Q       
Sbjct: 642  LKEELEKH-QSEQDENGWGEENESEELKSENENLKKQIEELKEQLNQKEDQGQEEN-GWC 699

Query: 1044 SDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNE--ELQILVREQDDQIKELKETKLT 1101
            ++ E+         E+++ E++++ K+    KQ+NE   L+  + E  +Q+K+ ++    
Sbjct: 700  NENET---------EDLKSEIEQLKKENETLKQNNETESLKKQIEELKEQLKQKEDQGQE 750

Query: 1102 FEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEE--EEFIQERSVL-- 1157
                  + E     S I  + ++   ++            LK + E  E+ ++E +    
Sbjct: 751  ENGWGEENETEDYKSQISALENEKRTLNKKIKDLANGLKTLKSKNEKLEQQLKENANNGN 810

Query: 1158 QEQSAKLNTELQECYTKIIQLETLNTELT-GHDVVNQE------QINQLKSKLEQLNTEN 1210
             + S  ++ E  E   KI +LE  N EL   ++ +++E      Q N+L S+ + L+ E 
Sbjct: 811  NDNSKDISVEFNETEEKITELEFENEELRRNNESLSEEKKTLHKQNNKLVSENKTLSDEV 870

Query: 1211 DNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHE-------------L 1257
              L   V EL     S  ++   EI  L +  L  RE + ++T++              +
Sbjct: 871  STLREQVEELEEETISTSNELRSEIEHL-RSELVVREQELEQTKNNNNNVNNNENNNSNV 929

Query: 1258 RVQLSAFESKY----EQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKY 1313
                S +E K     +QL +  QS +    N+ +  E + SL+ +++D ++    LQ + 
Sbjct: 930  HSDQSIYEEKISLLKQQLEELKQSQSSNNNNEELEKENI-SLKKEIEDLKQENEGLQNQL 988

Query: 1314 ADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSY--KQMQEQSILNIN 1371
             +     E    E EDE                    +   EN  +  +  + ++I N+ 
Sbjct: 989  FEGGETNENNNQEKEDEIHKLKSEIEELKKKLESSEQNKEEENNGWGDENTETENIDNLK 1048

Query: 1372 EENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSE-----IYQKTHEYTIT 1426
             E  +L K              ++ + + +  EL  QL   +SE        +  E T  
Sbjct: 1049 SEIEELNKKLDESIKSNDEKQKKIEEMKQENEELQTQLFENNSEEEINKFKSQVEELTQK 1108

Query: 1427 LTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESE----- 1481
            L + N + E ++ Q  +    I+DL  +KE E   L+ ++ +  N    +Q++ E     
Sbjct: 1109 LQESNQKNEELQSQTEKQNNEIDDLKKQKEEENEKLQKEISDLKNEISQLQQKEEENGSD 1168

Query: 1482 -IERVKLIEELNVKITESV-SLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDE 1539
              ++++++++ N K  E +  L KQ+ EL    E++  + N++++ L+N   EI + N++
Sbjct: 1169 LQKQIEVLKQTNEKNDEDIEQLAKQIDELQTEKEKQNEEINDLKSQLQNVS-EIKSENEK 1227

Query: 1540 ITNLQNMVRASSSKIQKHVSFASDTKQGRDEQL 1572
              N  + ++  + ++Q  + F     Q ++E++
Sbjct: 1228 QKNEIDDLKKENEELQTQL-FEIGNNQEKEEEI 1259



 Score =  165 bits (400), Expect = 1e-38
 Identities = 267/1359 (19%), Positives = 585/1359 (43%), Gaps = 118/1359 (8%)

Query: 212  EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271
            E+ + Q  K       ++ + ++E ++L K+I      IS L++  +             
Sbjct: 1117 EELQSQTEKQNNEIDDLKKQKEEENEKLQKEISDLKNEISQLQQKEEE----------NG 1166

Query: 272  SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSL--EIANMTELTKKIE 329
            S L +++E               LAKQ  E   E++ + EE   L  ++ N++E+  + E
Sbjct: 1167 SDLQKQIEVLKQTNEKNDEDIEQLAKQIDELQTEKEKQNEEINDLKSQLQNVSEIKSENE 1226

Query: 330  LLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPL--ISRKSGRNTASKMKSPWS 387
              ++    +++ N+EL+ +L  +G   +      K  S +  + +K   +  +K +    
Sbjct: 1227 KQKNEIDDLKKENEELQTQLFEIGNNQEKEEEIHKLKSEIEELKKKLEESEQNKEEENID 1286

Query: 388  QLSSE--TLNQDTDKKINKNE-IAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXG 444
             L SE  TL ++  +  + NE + K    +Q  NK L  ++    E++            
Sbjct: 1287 NLKSENETLKEEIKRLESDNEQLKKQNSELQQENKSLHQQQSKEEEENGWGEENESEELK 1346

Query: 445  KDTLIAQLQLEH------QQHMEGPSLIHVG--TNTEDVNEIAKVQEQLKQELNDEIKDV 496
             +    + Q+E       Q+  +G      G    TED        E  K+ LN +IKD+
Sbjct: 1347 SENESLKKQIEELKEQLKQKEDQGQEENGWGDENETEDYKSQISALENEKRTLNKKIKDL 1406

Query: 497  NVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKE 556
               + ++ LKS  E++ Q   +I++ N        N K    +  +T +  +++   N+E
Sbjct: 1407 --ANGLKTLKSKNEKLEQQLKDINSNNST----NDNSKDISVEFNETEEKITELEFENEE 1460

Query: 557  IVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAI 616
            + R  E L   S++   L+++   L          + +  +V     ++E L E  +   
Sbjct: 1461 LRRNNESL---SEEKKTLQKQNNKL------VSENKTLSDEVSTLREQVEELEEETISTS 1511

Query: 617  SLLESQKFDLVQELHILQQKYDEVEDKLADI-------SQLQSDQVCSEIKSVHLEEQID 669
            + L S+   L  EL + +Q+ ++ ++   ++       S + SDQ   E K   L++Q++
Sbjct: 1512 NELRSEIEHLRSELVLREQELEQTKNNNNNVNNNENNNSNVHSDQSIYEEKISLLKQQLE 1571

Query: 670  ALSASKKELALVIENLKLDK-EQLYGTIKDLENDKEDIMNKL----QNYIQENMDLTDKL 724
             L   +++     +N   D+  +L   I+DL+ + E++ N+L    +     N +  D++
Sbjct: 1572 ELKQQQQKPFDHEDNNDSDEINKLKKEIEDLKQENEELQNQLFEGGETNENNNQEKEDEI 1631

Query: 725  EKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEES 784
             K+ +E I EL  K+   EQ+K +   G   +  E +  IEN++SE+ +   ++  L +S
Sbjct: 1632 HKLKSE-IEELKKKLESSEQNKEEENNGWGDENTETE-NIENLKSEIEELNKKLNELSKS 1689

Query: 785  IAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVL---MDHDRV----- 836
                + +   LE+K  +  +   E+++   +   Q ++L  R A+     D + +     
Sbjct: 1690 NDEKQKKIEELEQKLQESQNNKDEEEENIEDLKEQLEQL-RRDAITKSKQDQEEIENLKK 1748

Query: 837  -VEKQLLEIEHENKELQ--KKNQILL-----EENQNLQISLSDMQQHYNALVEKANRTDL 888
             +E++  +IE   +EL+  +K+ I       EE + LQ  +   ++  + L  + +    
Sbjct: 1749 QIEEKEADIEEITEELEQLRKDSITKAKQDQEEIEKLQNEIQKQKEIIDNLNAEIDELGE 1808

Query: 889  AESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNE 948
             E+E    + +L+ L  +  +     Q  I +   E+ +L+ E     E+   D    NE
Sbjct: 1809 KEAEHEDLKDELQQLRKDSLQKAKIDQAEIDRLNAEVSNLKFELENGKENIWGDDDD-NE 1867

Query: 949  KYEKNI-EYVTQLEAQLQEYKNNIENLNMNVEEL-NKMNLELIDKHVQKQQTQSPDYTEQ 1006
            K+++ + E + +L++++++  + IE L   + +  +   ++  +K ++++  Q+     +
Sbjct: 1868 KHKETLTEIIEKLKSEIEDKNSEIEKLEEEISQFEDPTEVKQENKKLKEELDQALRQNAE 1927

Query: 1007 YIN---EINKLNALLKQKDE--EIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENME 1061
              N   E NKL   LKQ  +  E+  L +K+   +     +  D  +   QF  +L N  
Sbjct: 1928 LGNVNEENNKLREQLKQSIDTNELKTLEKKLKEKEEENQKLHDDLNT--LQF--ELNNSI 1983

Query: 1062 EEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMN--IPKTEGMIISSTIE 1119
              + ++++   +S +  +E++ L  E + ++ EL + KL  E N  + + E ++  +  E
Sbjct: 1984 AGLPKINQS--ESMEIRDEVERLANE-NKKLSELTK-KLEEEKNFLVSQLENVVQRNDYE 2039

Query: 1120 PMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLE 1179
                +   +             L +Q+ +E +++      + +   +EL+    ++ +L+
Sbjct: 2040 KELQNVEELKLKLKKAEKDNEEL-LQQIDELVEQNETENHEKSDAESELKSLKAELAKLK 2098

Query: 1180 TLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELW 1239
                E      V +E++++L  K+E+  T N  L + + +  +S +  + +  F+  +  
Sbjct: 2099 DSEKEYQ----VLREEVDELTQKIEESETINKELKTIIDQNDTSAAENMYKAQFDELKAL 2154

Query: 1240 KQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKL 1299
               L  +  D +K     + +++    +  +L  +++  TQ+ +N    +E++T+  + L
Sbjct: 2155 VSDLKSQNEDLKKDSENSKQEITKLTEEKTELNANIEKLTQDNSNLSSNVEKLTNEISNL 2214

Query: 1300 QDKEEHLRNLQEKYADVINQI-----------EILRSEIEDEKVAFXXXXXXXXXXXXXX 1348
            + +     N+      V N++           E  ++++E EK                 
Sbjct: 2215 KFQPTAQENVVPAETPVANEVKPSEEAVSTPNEDEKAKLESEKEELVKKNDEMMKQIVLM 2274

Query: 1349 XXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQ 1408
              ++  +N+ + QMQE+  +  NEEN  L+               +++   A VL L   
Sbjct: 2275 KNEIEKQNKEFAQMQER-FIKANEENMSLRN----VASKNKELETQLDQKTANVLSLRKD 2329

Query: 1409 LELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHE 1468
            ++    E +QK  +    L +   EF ++R++    E++   L  + E +    + +  E
Sbjct: 2330 IDNLKIE-FQK--DLDAKLAKAAKEFNDLRKKFRVVEQQRNQLAAQIEYDEQ--QKQTAE 2384

Query: 1469 NANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAE 1507
              N  ET  K+ +I+  + IE L   + +  S +++  E
Sbjct: 2385 AQNQSET--KKLQIDTFR-IEYLRATLLQFFSQDQKTQE 2420



 Score =  163 bits (397), Expect = 3e-38
 Identities = 304/1498 (20%), Positives = 611/1498 (40%), Gaps = 138/1498 (9%)

Query: 147  LSNTIKEKDNALSVLQVKMKIMETTILDLQEK---INEKDQIIEA-KNKATTXXXXXXXX 202
            L+  IK+  N L  L+ K + +E  + +        N KD  +E  + +           
Sbjct: 777  LNKKIKDLANGLKTLKSKNEKLEQQLKENANNGNNDNSKDISVEFNETEEKITELEFENE 836

Query: 203  XXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIES-KDVRISSLEEANKLLE 261
                      + K+ + K     ++      DE   L + +E  ++  IS+  E    +E
Sbjct: 837  ELRRNNESLSEEKKTLHKQNNKLVSENKTLSDEVSTLREQVEELEEETISTSNELRSEIE 896

Query: 262  AARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSI--EPSCEEKTEIEEKGSLEIA 319
              R E+ +   +L Q                   + QSI  E     K ++EE    + +
Sbjct: 897  HLRSELVVREQELEQTKNNNNNVNNNENNNSNVHSDQSIYEEKISLLKQQLEELKQSQSS 956

Query: 320  NMT--ELTKK-IELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGR 376
            N    EL K+ I L + +   ++Q N+ L+N+L   G  ++  ++  +K   +   KS  
Sbjct: 957  NNNNEELEKENISLKKEIE-DLKQENEGLQNQLFEGGETNE--NNNQEKEDEIHKLKSEI 1013

Query: 377  NTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXX 436
                K      Q   E  N   D+      I  L+  I+ LNK L +    I   D    
Sbjct: 1014 EELKKKLESSEQNKEEENNGWGDENTETENIDNLKSEIEELNKKLDES---IKSNDEKQK 1070

Query: 437  XXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDV 496
                     + L  QL  E+    E   +    +  E++ +  +   Q  +EL  + +  
Sbjct: 1071 KIEEMKQENEELQTQL-FENNSEEE---INKFKSQVEELTQKLQESNQKNEELQSQTEKQ 1126

Query: 497  NVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKE 556
            N  ++ +  K  EE+  +L  EI      + +++   +     +QK I+   + ++ N E
Sbjct: 1127 N-NEIDDLKKQKEEENEKLQKEISDLKNEISQLQQKEEENGSDLQKQIEVLKQTNEKNDE 1185

Query: 557  IVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAI 616
                  ++  L++++ EL+ EK      + D  S     S++  +  + +N  +   K  
Sbjct: 1186 ------DIEQLAKQIDELQTEKEKQNEEINDLKSQLQNVSEIKSENEKQKNEIDDLKKEN 1239

Query: 617  SLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKK 676
              L++Q F++       Q+K +E+    ++I +L+     SE      EE ID L +  +
Sbjct: 1240 EELQTQLFEIGNN----QEKEEEIHKLKSEIEELKKKLEESEQNKE--EENIDNLKSENE 1293

Query: 677  ELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQEN-MDLTDKLEKMSAE----- 730
             L   I+ L+ D EQL     +L+ + + +  +     +EN     ++ E++ +E     
Sbjct: 1294 TLKEEIKRLESDNEQLKKQNSELQQENKSLHQQQSKEEEENGWGEENESEELKSENESLK 1353

Query: 731  -KISELLAKINH-EEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVM 788
             +I EL  ++   E+Q + +  +G + + ++    I  +E+E      +I  L   +  +
Sbjct: 1354 KQIEELKEQLKQKEDQGQEENGWGDENETEDYKSQISALENEKRTLNKKIKDLANGLKTL 1413

Query: 789  EDRRYSLERKADQLGSY-------------LQEKQKAYSEYTIQEDELVNRLAVLMDHDR 835
            + +   LE++   + S                E ++  +E   + +EL      L +  +
Sbjct: 1414 KSKNEKLEQQLKDINSNNSTNDNSKDISVEFNETEEKITELEFENEELRRNNESLSEEKK 1473

Query: 836  VVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLA----ES 891
             ++KQ  ++  ENK L  +   L E+ + L+           + +E   R++L     E 
Sbjct: 1474 TLQKQNNKLVSENKTLSDEVSTLREQVEELEEETISTSNELRSEIEHL-RSELVLREQEL 1532

Query: 892  ESTKYQTQLRDLESNLKRITHEHQTLIVQK----KKEIEDL--------EIEFNTQIESA 939
            E TK      +   N     H  Q++  +K    K+++E+L        + E N   +  
Sbjct: 1533 EQTKNNNNNVNNNENNNSNVHSDQSIYEEKISLLKQQLEELKQQQQKPFDHEDNNDSDEI 1592

Query: 940  IRDKKVLNEKYEKNIEYVTQL-------EAQLQEYKNNIENLNMNVEELNKMNLELIDKH 992
             + KK + +  ++N E   QL       E   QE ++ I  L   +EEL K  LE  +++
Sbjct: 1593 NKLKKEIEDLKQENEELQNQLFEGGETNENNNQEKEDEIHKLKSEIEELKK-KLESSEQN 1651

Query: 993  VQKQ---------QTQSPDYTEQYINEINK-LNALLKQKDEE---IIALNQKINNAQVSY 1039
             +++         +T++ +  +  I E+NK LN L K  DE+   I  L QK+  +Q + 
Sbjct: 1652 KEEENNGWGDENTETENIENLKSEIEELNKKLNELSKSNDEKQKKIEELEQKLQESQNNK 1711

Query: 1040 ---MSMVSDYESKLAQFT----TKLENMEEEMQRVSKQLLDSKQHNEEL-QILVREQDDQ 1091
                  + D + +L Q      TK +  +EE++ + KQ+ + +   EE+ + L + + D 
Sbjct: 1712 DEEEENIEDLKEQLEQLRRDAITKSKQDQEEIENLKKQIEEKEADIEEITEELEQLRKDS 1771

Query: 1092 IKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFI 1151
            I + K+ +   E    + E       I+ ++ + + +             L+ Q  ++ +
Sbjct: 1772 ITKAKQDQEEIEKL--QNEIQKQKEIIDNLNAEIDELGEKEAEHEDLKDELQ-QLRKDSL 1828

Query: 1152 QERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTEND 1211
            Q+  + Q +  +LN E+        +LE     + G D  N++    L   +E+L +E +
Sbjct: 1829 QKAKIDQAEIDRLNAEVSNLK---FELENGKENIWGDDDDNEKHKETLTEIIEKLKSEIE 1885

Query: 1212 NLLSTVAELRSSIS-----SAVDQRGFEIAELWKQHLAQRE--ADFQKTEHELRVQLS-A 1263
            +  S + +L   IS     + V Q   ++ E   Q L Q     +  +  ++LR QL  +
Sbjct: 1886 DKNSEIEKLEEEISQFEDPTEVKQENKKLKEELDQALRQNAELGNVNEENNKLREQLKQS 1945

Query: 1264 FESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEIL 1323
             ++   + L+      +EE  K+   + + +LQ +L +    L  + +  +  I   E+ 
Sbjct: 1946 IDTNELKTLEKKLKEKEEENQKL--HDDLNTLQFELNNSIAGLPKINQSESMEIRD-EVE 2002

Query: 1324 RSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSY-KQMQEQSILNIN-----EENAQL 1377
            R   E++K++                 +   +   Y K++Q    L +      ++N +L
Sbjct: 2003 RLANENKKLSELTKKLEEEKNFLVSQLENVVQRNDYEKELQNVEELKLKLKKAEKDNEEL 2062

Query: 1378 KKSSXXXXXXXXXXXXRVNDAEAKVLELTHQL-ELKDSEI-YQKTHEYTITLTQRNDEFE 1435
             +                +DAE+++  L  +L +LKDSE  YQ   E    LTQ+ +E E
Sbjct: 2063 LQQIDELVEQNETENHEKSDAESELKSLKAELAKLKDSEKEYQVLREEVDELTQKIEESE 2122

Query: 1436 NVRQQLVEYEKRIEDLTYEK--ESELAILRLKMHENANHYETMQKESEIERVKLIEELNV 1493
             + ++L     + +    E   +++   L+  + +  +  E ++K+SE  + ++      
Sbjct: 2123 TINKELKTIIDQNDTSAAENMYKAQFDELKALVSDLKSQNEDLKKDSENSKQEI-----T 2177

Query: 1494 KITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASS 1551
            K+TE      +  ELN  +E+     + + + +E    EI  L  + T  +N+V A +
Sbjct: 2178 KLTE------EKTELNANIEKLTQDNSNLSSNVEKLTNEISNLKFQPTAQENVVPAET 2229



 Score =  163 bits (395), Expect = 5e-38
 Identities = 283/1372 (20%), Positives = 579/1372 (42%), Gaps = 122/1372 (8%)

Query: 295  LAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGT 354
            LAK+         T  +    LE   + E  +KIE LE  N  ++  N EL+ ++     
Sbjct: 85   LAKEIENMKNTTSTASQNDSGLEEV-VQEFEQKIETLESENKTMKDQNSELQQQI----Q 139

Query: 355  ESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVI 414
            + K ++      S  + +K   N  S+ KS    L     +QD      K E+ + ++  
Sbjct: 140  QYKELTDKLSTESTELQQKM-ENIKSEDKSAEETLLQTISDQDIQINKLKEELEQAKLAA 198

Query: 415  QSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTED 474
             S  ++         E +            KD+L  ++     Q  E   L    + + +
Sbjct: 199  NSSEQNTNAFAQKEQELNAQITDLKNQLAAKDSLSDEIASLKAQIAE---LNQNNSKSSE 255

Query: 475  VNEIAKVQEQLKQELNDEIKDVN-VKDLIEKLKSAEEQITQLNDEI-DAANKNMIKVKSN 532
             NE  K + Q     +D+  D++ +K  + +LK   +QI Q + EI D    NM     N
Sbjct: 256  ENEQLKAESQKDASSDDKNSDLSRLKKAVVQLK---KQIAQKDQEINDLKTSNMQLQNFN 312

Query: 533  HK---LKLKQMQKTIDNFSKVSDSNK-EIVRL----TEELHHLSQKVAELEEEKGNLQLH 584
            ++   +++++ +  I  F K+ +S K E  +L    T  +  L  ++ +L++E   LQ  
Sbjct: 313  NETQNVEIEKYKSQIIEFQKIIESLKAENAKLQTENTNTVDKLQSEIEKLKQENSELQNQ 372

Query: 585  LVDYDSG---RMIESDVYKKMIEMENLAETRLKAISLLESQKFDLV----QELHILQQKY 637
            + + + G      E ++  ++ E++   E   K+ S    Q   ++    +++  L+QK 
Sbjct: 373  IQENEDGWNDNNNEEELQNQITELQKQLEENKKSYSEETEQLKQIIDDDSKQIEDLKQKL 432

Query: 638  DEVED----KLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLY 693
             E +D      + +++LQ+++   + K V +   +  L          I  L  +   L 
Sbjct: 433  AEAQDHEGNSDSQLAKLQTEKQQLDKKLVDVANALRKLKTKNDNDQATISKLNEENSSLQ 492

Query: 694  GTIKDL----------ENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEE 743
              I++L          E + +++  +LQ+   +N D+  + E +  E      ++   ++
Sbjct: 493  KQIEELKQQTANNASYEAEIQNLKKQLQDLQIQNDDIKTENEHLQQEMFENNKSEEIEQQ 552

Query: 744  QSKI-QTQFGIDAK---IQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKA 799
            + +I + Q  I +K   IQ ++  IEN+  E+ + K     L E +    +   S + + 
Sbjct: 553  KKQISELQKEISSKSSEIQAKNDEIENLNKEIEQIKKENQELNEEL-FQNNENNSNDEEI 611

Query: 800  DQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILL 859
            ++L + +Q  QK  S+ + Q +   +++  L +    +EK   E +      + +++ L 
Sbjct: 612  EKLKTQIQSLQKEISDLSQQNNNYKSQVEELKEE---LEKHQSEQDENGWGEENESEELK 668

Query: 860  EENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTL-- 917
             EN+NL+  + ++++  N   ++       E      + +  DL+S ++++  E++TL  
Sbjct: 669  SENENLKKQIEELKEQLNQKEDQGQ-----EENGWCNENETEDLKSEIEQLKKENETLKQ 723

Query: 918  ---IVQKKKEIEDLEIEFNTQIESAIRD----KKVLNEKYEKNIEYVTQ----LEAQLQE 966
                   KK+IE+L+ +   + +    +    ++   E Y+  I  +      L  ++++
Sbjct: 724  NNETESLKKQIEELKEQLKQKEDQGQEENGWGEENETEDYKSQISALENEKRTLNKKIKD 783

Query: 967  YKNNIENL---NMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDE 1023
              N ++ L   N  +E+  K N    +    K  +   + TE+ I E+   N  L++ +E
Sbjct: 784  LANGLKTLKSKNEKLEQQLKENANNGNNDNSKDISVEFNETEEKITELEFENEELRRNNE 843

Query: 1024 EIIALNQ---KINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEE 1080
             +    +   K NN  VS    +SD  S L +   ++E +EEE    S +L    +H   
Sbjct: 844  SLSEEKKTLHKQNNKLVSENKTLSDEVSTLRE---QVEELEEETISTSNELRSEIEHLRS 900

Query: 1081 LQILVREQD-DQIK---------ELKETKLTFEMNIPKTEGMIISSTIEPM----SDDAN 1126
             +++VREQ+ +Q K         E   + +  + +I + +  ++   +E +    S + N
Sbjct: 901  -ELVVREQELEQTKNNNNNVNNNENNNSNVHSDQSIYEEKISLLKQQLEELKQSQSSNNN 959

Query: 1127 NVDXXXXXXXXXXXXLKVQEEEEFIQERSVL-QEQSAKLNTELQECYTKI-IQLETLNTE 1184
            N +              +++E E +Q +     E +   N E ++   K+  ++E L  +
Sbjct: 960  NEELEKENISLKKEIEDLKQENEGLQNQLFEGGETNENNNQEKEDEIHKLKSEIEELKKK 1019

Query: 1185 LTGHDVVNQEQINQLKSKLEQLNTEN-DNLLSTVAELRSSISSAVDQRGFEIAELWKQHL 1243
            L   +   +E+ N      E   TEN DNL S + EL   +  ++     +  ++ +   
Sbjct: 1020 LESSEQNKEEENNGWGD--ENTETENIDNLKSEIEELNKKLDESIKSNDEKQKKIEEMKQ 1077

Query: 1244 AQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQE-ETNKIVTMEQVTSLQNKLQDK 1302
               E   Q  E+    +++ F+S+ E+L   +Q S Q+ E  +  T +Q   + +  + K
Sbjct: 1078 ENEELQTQLFENNSEEEINKFKSQVEELTQKLQESNQKNEELQSQTEKQNNEIDDLKKQK 1137

Query: 1303 EEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQM 1362
            EE    LQ++ +D+ N+I  L+ + E+                     D+    +   ++
Sbjct: 1138 EEENEKLQKEISDLKNEISQLQQKEEENGSDLQKQIEVLKQTNEKNDEDIEQLAKQIDEL 1197

Query: 1363 Q---EQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQL------ELKD 1413
            Q   E+    IN+  +QL+  S             ++D + +  EL  QL      + K+
Sbjct: 1198 QTEKEKQNEEINDLKSQLQNVS-EIKSENEKQKNEIDDLKKENEELQTQLFEIGNNQEKE 1256

Query: 1414 SEIYQKTHEY-----TITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLK--- 1465
             EI++   E       +  +++N E EN+     E E   E++    ES+   L+ +   
Sbjct: 1257 EEIHKLKSEIEELKKKLEESEQNKEEENIDNLKSENETLKEEIK-RLESDNEQLKKQNSE 1315

Query: 1466 -MHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQT 1524
               EN + ++   KE E        E     +E+ SL KQ+ EL + L+++  +  E   
Sbjct: 1316 LQQENKSLHQQQSKEEEENGWGEENESEELKSENESLKKQIEELKEQLKQKEDQGQEENG 1375

Query: 1525 ALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTM 1576
              +  E E      +I+ L+N  R  + KI K ++    T + ++E+L+  +
Sbjct: 1376 WGDENETE--DYKSQISALENEKRTLNKKI-KDLANGLKTLKSKNEKLEQQL 1424



 Score =  161 bits (392), Expect = 1e-37
 Identities = 296/1481 (19%), Positives = 623/1481 (42%), Gaps = 139/1481 (9%)

Query: 174  DLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQE---NFIAMEA 230
            +LQ +I E  + +E   K+ +                 ED KQ++ + Q+   N  +  A
Sbjct: 388  ELQNQITELQKQLEENKKSYSEETEQLKQIIDDDSKQIEDLKQKLAEAQDHEGNSDSQLA 447

Query: 231  EWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXX 290
            + + EKQ+L K +      +  L+  N   +A   +++ E+S L +++E+          
Sbjct: 448  KLQTEKQQLDKKLVDVANALRKLKTKNDNDQATISKLNEENSSLQKQIEELKQQTANNAS 507

Query: 291  XXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNK--ELENK 348
                +  Q+++   ++         L+I N    T+     EHL  ++ + NK  E+E +
Sbjct: 508  YEAEI--QNLKKQLQD---------LQIQNDDIKTEN----EHLQQEMFENNKSEEIEQQ 552

Query: 349  LATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIA 408
               +    K +SS S +           N   +     +Q  +E L Q+ +   N  EI 
Sbjct: 553  KKQISELQKEISSKSSEIQAKNDEIENLNKEIEQIKKENQELNEELFQNNENNSNDEEIE 612

Query: 409  KLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHV 468
            KL+  IQSL K++ D    +S+++            K+ L  + Q E  ++  G      
Sbjct: 613  KLKTQIQSLQKEISD----LSQQNNNYKSQVEEL--KEEL-EKHQSEQDENGWGEENESE 665

Query: 469  GTNTEDVNEIAKVQEQLKQELN---DEIKDVNV---KDLIEKLKSAEEQITQLNDEIDAA 522
               +E+ N + K  E+LK++LN   D+ ++ N    ++  E LKS  EQ+ + N+ +   
Sbjct: 666  ELKSENEN-LKKQIEELKEQLNQKEDQGQEENGWCNENETEDLKSEIEQLKKENETLKQN 724

Query: 523  NKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQ 582
            N+     K   +LK +Q+++  D   + +   +E      E      +++ LE EK  L 
Sbjct: 725  NETESLKKQIEELK-EQLKQKEDQGQEENGWGEE-----NETEDYKSQISALENEKRTLN 778

Query: 583  LHLVDYDSG-RMIESDVYKKMIEMENLAET----RLKAISLLESQKFDLVQELHILQQKY 637
              + D  +G + ++S   K   +++  A        K IS+  ++  + + EL    ++ 
Sbjct: 779  KKIKDLANGLKTLKSKNEKLEQQLKENANNGNNDNSKDISVEFNETEEKITELEFENEEL 838

Query: 638  DEVEDKLADISQL---QSDQVCSEIKSVH-----LEEQIDALS----ASKKELALVIENL 685
                + L++  +    Q++++ SE K++      L EQ++ L     ++  EL   IE+L
Sbjct: 839  RRNNESLSEEKKTLHKQNNKLVSENKTLSDEVSTLREQVEELEEETISTSNELRSEIEHL 898

Query: 686  KLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQS 745
            + +       ++  +N+  ++ N   N    + D     + +  EKIS  L K   EE  
Sbjct: 899  RSELVVREQELEQTKNNNNNVNNNENNNSNVHSD-----QSIYEEKIS--LLKQQLEELK 951

Query: 746  KIQTQFGIDAKIQERDLYIENIESELSKYKSRIC-RLEESIAVMEDRRYSLERKADQLGS 804
            + Q+    + ++++ ++ ++    +L +    +  +L E     E+     E +  +L S
Sbjct: 952  QSQSSNNNNEELEKENISLKKEIEDLKQENEGLQNQLFEGGETNENNNQEKEDEIHKLKS 1011

Query: 805  YLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQN 864
             ++E +K        ++E  N           ++    EIE  NK+L +     ++ N  
Sbjct: 1012 EIEELKKKLESSEQNKEEENNGWGDENTETENIDNLKSEIEELNKKLDES----IKSNDE 1067

Query: 865  LQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKK- 923
             Q  + +M+Q    L  +    + +E E  K+++Q+ +L   L+    +++ L  Q +K 
Sbjct: 1068 KQKKIEEMKQENEELQTQLFENN-SEEEINKFKSQVEELTQKLQESNQKNEELQSQTEKQ 1126

Query: 924  --EIEDLEI---EFNTQIESAIRD-KKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMN 977
              EI+DL+    E N +++  I D K  +++  +K  E  + L+ Q++  K   E  + +
Sbjct: 1127 NNEIDDLKKQKEEENEKLQKEISDLKNEISQLQQKEEENGSDLQKQIEVLKQTNEKNDED 1186

Query: 978  VEELNKMNLEL-IDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQ 1036
            +E+L K   EL  +K  Q ++        Q ++EI   N   KQK+E I  L ++    Q
Sbjct: 1187 IEQLAKQIDELQTEKEKQNEEINDLKSQLQNVSEIKSENE--KQKNE-IDDLKKENEELQ 1243

Query: 1037 VSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELK 1096
                 + ++ E +      ++  ++ E++ + K+L +S+Q+ EE      E  D +K   
Sbjct: 1244 TQLFEIGNNQEKE-----EEIHKLKSEIEELKKKLEESEQNKEE------ENIDNLKSEN 1292

Query: 1097 ETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSV 1156
            ET L  E+   +++   +      +  +  ++              +  E EE   E   
Sbjct: 1293 ET-LKEEIKRLESDNEQLKKQNSELQQENKSLHQQQSKEEEENGWGEENESEELKSENES 1351

Query: 1157 LQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLST 1216
            L++Q  +L  +L++   +  +      E    D   + QI+ L+++   LN +  +L + 
Sbjct: 1352 LKKQIEELKEQLKQKEDQGQEENGWGDENETEDY--KSQISALENEKRTLNKKIKDLANG 1409

Query: 1217 VAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFES----KYEQLL 1272
            +  L+S  +  ++Q+  +I      +   ++   +  E E ++    FE+    +  + L
Sbjct: 1410 LKTLKSK-NEKLEQQLKDINSNNSTNDNSKDISVEFNETEEKITELEFENEELRRNNESL 1468

Query: 1273 DSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKV 1332
               + + Q++ NK+V+  +  +L +++    E +  L+E+     N+   LRSEIE  + 
Sbjct: 1469 SEEKKTLQKQNNKLVSENK--TLSDEVSTLREQVEELEEETISTSNE---LRSEIEHLRS 1523

Query: 1333 AFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILN-----INEENAQLKKSSXX-XXX 1386
                                  EN +     +QSI       + ++  +LK+        
Sbjct: 1524 ELVLREQELEQTKNNNNNVNNNENNNSNVHSDQSIYEEKISLLKQQLEELKQQQQKPFDH 1583

Query: 1387 XXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEK 1446
                    +N  + ++ +L  + E   +++++          ++ DE   ++ ++ E +K
Sbjct: 1584 EDNNDSDEINKLKKEIEDLKQENEELQNQLFEGGETNENNNQEKEDEIHKLKSEIEELKK 1643

Query: 1447 RIEDLTYEKE--------------------SELAILRLKMHENANHYETMQKESEIERVK 1486
            ++E     KE                    SE+  L  K++E +   +  QK+ E    K
Sbjct: 1644 KLESSEQNKEEENNGWGDENTETENIENLKSEIEELNKKLNELSKSNDEKQKKIEELEQK 1703

Query: 1487 LIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALEN-------QEIEIVTLNDE 1539
            L E  N K  E  ++     +L +   + + K+ + Q  +EN       +E +I  + +E
Sbjct: 1704 LQESQNNKDEEEENIEDLKEQLEQLRRDAITKSKQDQEEIENLKKQIEEKEADIEEITEE 1763

Query: 1540 ITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKEL 1580
            +  L+      + + Q+ +    +  Q + E +DN +N E+
Sbjct: 1764 LEQLRKDSITKAKQDQEEIEKLQNEIQKQKEIIDN-LNAEI 1803



 Score =  161 bits (392), Expect = 1e-37
 Identities = 282/1405 (20%), Positives = 586/1405 (41%), Gaps = 142/1405 (10%)

Query: 212  EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271
            E+ K+++   ++N       W DE      + E+ D   S +EE NK L+ +  + + E 
Sbjct: 1014 EELKKKLESSEQNKEEENNGWGDENT----ETENIDNLKSEIEELNKKLDES-IKSNDEK 1068

Query: 272  SKLAQELEQXXXXXXXXXXXXXXLAK-QSIEPSCEEKTE-IEEKGSLEIANMTELTKKIE 329
             K  +E++Q                +    +   EE T+ ++E         ++  K+  
Sbjct: 1069 QKKIEEMKQENEELQTQLFENNSEEEINKFKSQVEELTQKLQESNQKNEELQSQTEKQNN 1128

Query: 330  LLEHLNCQIRQTNKELENKLATMGTE-SKAVSSPSKKGSPLISR-KSGRNTASKMKSPWS 387
             ++ L  Q  + N++L+ +++ +  E S+      + GS L  + +  + T  K      
Sbjct: 1129 EIDDLKKQKEEENEKLQKEISDLKNEISQLQQKEEENGSDLQKQIEVLKQTNEKNDEDIE 1188

Query: 388  QLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDT 447
            QL+ +     T+K+    EI  L+  +Q++++       + SE +             + 
Sbjct: 1189 QLAKQIDELQTEKEKQNEEINDLKSQLQNVSE-------IKSENEKQKNEIDDLKKENEE 1241

Query: 448  LIAQLQLEHQQHMEGPSLIH-VGTNTEDVNEIAKVQEQLKQELN-DEIKDVN--VKDLIE 503
            L  QL  E   + E    IH + +  E++ +  +  EQ K+E N D +K  N  +K+ I+
Sbjct: 1242 LQTQL-FEIGNNQEKEEEIHKLKSEIEELKKKLEESEQNKEEENIDNLKSENETLKEEIK 1300

Query: 504  KLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEE 563
            +L+S  EQ+ + N E+   NK++ + +S  + +    ++  +   ++   N+ + +  EE
Sbjct: 1301 RLESDNEQLKKQNSELQQENKSLHQQQSKEEEENGWGEE--NESEELKSENESLKKQIEE 1358

Query: 564  L-HHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIE-MENLAETRLKAISLLES 621
            L   L QK  + +EE G           G   E++ YK  I  +EN   T  K I     
Sbjct: 1359 LKEQLKQKEDQGQEENG----------WGDENETEDYKSQISALENEKRTLNKKIK---- 1404

Query: 622  QKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALV 681
               DL   L  L+ K +++E +L DI+   S    S+  SV   E  + ++    EL   
Sbjct: 1405 ---DLANGLKTLKSKNEKLEQQLKDINSNNSTNDNSKDISVEFNETEEKIT----ELEFE 1457

Query: 682  IENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKIS---ELLAK 738
             E L+ + E L    K L+     ++++ +    E   L +++E++  E IS   EL ++
Sbjct: 1458 NEELRRNNESLSEEKKTLQKQNNKLVSENKTLSDEVSTLREQVEELEEETISTSNELRSE 1517

Query: 739  INH-------EEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDR 791
            I H        EQ   QT+   +  +   +    N+ S+ S Y+ +I  L++ +  ++ +
Sbjct: 1518 IEHLRSELVLREQELEQTKNN-NNNVNNNENNNSNVHSDQSIYEEKISLLKQQLEELKQQ 1576

Query: 792  RYS-LERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAV--------LMDHDRVVEKQLL 842
            +    + + +     + + +K   +   + +EL N+L            + +  + K   
Sbjct: 1577 QQKPFDHEDNNDSDEINKLKKEIEDLKQENEELQNQLFEGGETNENNNQEKEDEIHKLKS 1636

Query: 843  EIEHENKELQKKNQILLEENQNLQISLSDMQ--QHYNALVEKANR--TDLAESESTKYQT 898
            EIE   K+L+   Q   EEN       ++ +  ++  + +E+ N+   +L++S   K Q 
Sbjct: 1637 EIEELKKKLESSEQNKEEENNGWGDENTETENIENLKSEIEELNKKLNELSKSNDEK-QK 1695

Query: 899  QLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVT 958
            ++ +LE  L+    E Q    ++++ IEDL+ +       AI   K   E+ E   + + 
Sbjct: 1696 KIEELEQKLQ----ESQNNKDEEEENIEDLKEQLEQLRRDAITKSKQDQEEIENLKKQIE 1751

Query: 959  QLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALL 1018
            + EA ++E    +E L  +     K + E I+K   + Q Q     ++ I+ +N     L
Sbjct: 1752 EKEADIEEITEELEQLRKDSITKAKQDQEEIEKLQNEIQKQ-----KEIIDNLNAEIDEL 1806

Query: 1019 KQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLL----DS 1074
             +K+ E   L  ++   +   +      ++++ +   ++ N++ E++   + +     D+
Sbjct: 1807 GEKEAEHEDLKDELQQLRKDSLQKAKIDQAEIDRLNAEVSNLKFELENGKENIWGDDDDN 1866

Query: 1075 KQHNEELQILVR----EQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDX 1130
            ++H E L  ++     E +D+  E+++ +         TE    +  ++   D A   + 
Sbjct: 1867 EKHKETLTEIIEKLKSEIEDKNSEIEKLEEEISQFEDPTEVKQENKKLKEELDQALRQNA 1926

Query: 1131 XXXXXXXXXXXLKVQEEEEF-IQERSVLQEQSAKLNTELQECYTKIIQLE-TLNTELTGH 1188
                       L+ Q ++     E   L+++  +   E Q+ +  +  L+  LN  + G 
Sbjct: 1927 ELGNVNEENNKLREQLKQSIDTNELKTLEKKLKEKEEENQKLHDDLNTLQFELNNSIAGL 1986

Query: 1189 DVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQR-- 1246
              +NQ +  +++ ++E+L  EN  L    +EL   +    +++ F +++L  +++ QR  
Sbjct: 1987 PKINQSESMEIRDEVERLANENKKL----SELTKKLE---EEKNFLVSQL--ENVVQRND 2037

Query: 1247 -EADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEH 1305
             E + Q  E EL+++L   E   E+LL  +             +EQ  +  ++  D E  
Sbjct: 2038 YEKELQNVE-ELKLKLKKAEKDNEELLQQIDE----------LVEQNETENHEKSDAESE 2086

Query: 1306 LRNLQEKYA---DVINQIEILRSEIED--EKVAFXXXXXXXXXXXXXXXXDLRTENQSYK 1360
            L++L+ + A   D   + ++LR E+++  +K+                      EN    
Sbjct: 2087 LKSLKAELAKLKDSEKEYQVLREEVDELTQKIEESETINKELKTIIDQNDTSAAENMYKA 2146

Query: 1361 QMQEQSIL--NINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQ 1418
            Q  E   L  ++  +N  LKK S               +  A + +LT       S + +
Sbjct: 2147 QFDELKALVSDLKSQNEDLKKDSENSKQEITKLTEEKTELNANIEKLTQDNSNLSSNVEK 2206

Query: 1419 KTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQK 1478
             T+E +      N +F+   Q+ V             E+ +A      +E     E +  
Sbjct: 2207 LTNEIS------NLKFQPTAQENV----------VPAETPVA------NEVKPSEEAVST 2244

Query: 1479 ESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLND 1538
             +E E+ KL  E    + ++  + KQ+  +   +E++  +  +MQ        E ++L +
Sbjct: 2245 PNEDEKAKLESEKEELVKKNDEMMKQIVLMKNEIEKQNKEFAQMQERFIKANEENMSLRN 2304

Query: 1539 EITNLQNMVRASSSKIQKHVSFASD 1563
              +  + +      K    +S   D
Sbjct: 2305 VASKNKELETQLDQKTANVLSLRKD 2329



 Score = 98.3 bits (234), Expect = 2e-18
 Identities = 183/921 (19%), Positives = 395/921 (42%), Gaps = 105/921 (11%)

Query: 728  SAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAV 787
            S  K +++L +   E Q++IQ     DA I+ER+     + +EL++   +I   EE   +
Sbjct: 28   SLSKENDILKRTQAEYQAQIQKCS--DALIEERET-TATLTNELAECDKKI---EEKEKL 81

Query: 788  MEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHE 847
            +ED    +E   +   +  Q       E  +QE E   ++  L   ++ ++ Q       
Sbjct: 82   IEDLAKEIENMKNTTSTASQNDSGL--EEVVQEFE--QKIETLESENKTMKDQ------- 130

Query: 848  NKELQKKNQILLEENQNLQISLSDMQQHY-NALVEKANRTDLAESESTKYQTQLRDLESN 906
            N ELQ++ Q   E    L    +++QQ   N   E  +  +      +    Q+  L+  
Sbjct: 131  NSELQQQIQQYKELTDKLSTESTELQQKMENIKSEDKSAEETLLQTISDQDIQINKLKEE 190

Query: 907  LKRI------THEHQTLIVQKKKE----IEDLEIE------FNTQIESAIRDKKVLNEKY 950
            L++       + ++     QK++E    I DL+ +       + +I S       LN+  
Sbjct: 191  LEQAKLAANSSEQNTNAFAQKEQELNAQITDLKNQLAAKDSLSDEIASLKAQIAELNQNN 250

Query: 951  EKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTE--QYI 1008
             K+ E   QL+A+ Q+  ++ ++ N ++  L K  ++L  +  QK Q  +   T   Q  
Sbjct: 251  SKSSEENEQLKAESQKDASS-DDKNSDLSRLKKAVVQLKKQIAQKDQEINDLKTSNMQLQ 309

Query: 1009 NEINKL-NALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRV 1067
            N  N+  N  +++   +II   + I + +     + ++  + + +  +++E +++E   +
Sbjct: 310  NFNNETQNVEIEKYKSQIIEFQKIIESLKAENAKLQTENTNTVDKLQSEIEKLKQENSEL 369

Query: 1068 SKQLLDSK------QHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPM 1121
              Q+ +++       + EELQ  + E     K+L+E K ++     + +  II    + +
Sbjct: 370  QNQIQENEDGWNDNNNEEELQNQITELQ---KQLEENKKSYSEETEQLK-QIIDDDSKQI 425

Query: 1122 SDDANNVDXXXXXXXXXXXXL-KVQEEEEFIQERSV-LQEQSAKLNTELQECYTKIIQLE 1179
             D    +             L K+Q E++ + ++ V +     KL T+       I +L 
Sbjct: 426  EDLKQKLAEAQDHEGNSDSQLAKLQTEKQQLDKKLVDVANALRKLKTKNDNDQATISKLN 485

Query: 1180 TLNTEL----------TGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSI----- 1224
              N+ L          T ++   + +I  LK +L+ L  +ND++ +    L+  +     
Sbjct: 486  EENSSLQKQIEELKQQTANNASYEAEIQNLKKQLQDLQIQNDDIKTENEHLQQEMFENNK 545

Query: 1225 SSAVDQRGFEIAELWKQHLAQREADFQKTEHE---LRVQLSAFESKYEQLLDSV-----Q 1276
            S  ++Q+  +I+EL K+ ++ + ++ Q    E   L  ++   + + ++L + +      
Sbjct: 546  SEEIEQQKKQISELQKE-ISSKSSEIQAKNDEIENLNKEIEQIKKENQELNEELFQNNEN 604

Query: 1277 SSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDE---KVA 1333
            +S  EE  K+ T  Q+ SLQ ++ D  +   N + +  ++  ++E  +SE ++    +  
Sbjct: 605  NSNDEEIEKLKT--QIQSLQKEISDLSQQNNNYKSQVEELKEELEKHQSEQDENGWGEEN 662

Query: 1334 FXXXXXXXXXXXXXXXXDLRTE-NQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXX 1392
                             +L+ + NQ   Q QE++    NE   +  KS            
Sbjct: 663  ESEELKSENENLKKQIEELKEQLNQKEDQGQEENGW-CNENETEDLKSEIEQLKKENETL 721

Query: 1393 XRVNDAEA---KVLELTHQLELKDSEIYQ--------KTHEYTITLTQRNDEFENVRQQL 1441
             + N+ E+   ++ EL  QL+ K+ +  +        +T +Y   ++   +E   + +++
Sbjct: 722  KQNNETESLKKQIEELKEQLKQKEDQGQEENGWGEENETEDYKSQISALENEKRTLNKKI 781

Query: 1442 VEYEKRIEDLTYEKESELAILRLKMHENANH-YETMQKESEIERVKLIEELNVKITESVS 1500
             +    ++ L  + E     L  ++ ENAN+      K+  +E      E   KITE   
Sbjct: 782  KDLANGLKTLKSKNEK----LEQQLKENANNGNNDNSKDISVE----FNETEEKITELEF 833

Query: 1501 LNKQVAELNKALEEEVAKTNEMQTAL--ENQEI--EIVTLNDEITNLQNMVRASSSKIQK 1556
             N+++   N++L EE    ++    L  EN+ +  E+ TL +++  L+    ++S++++ 
Sbjct: 834  ENEELRRNNESLSEEKKTLHKQNNKLVSENKTLSDEVSTLREQVEELEEETISTSNELRS 893

Query: 1557 HVSFASDTKQGRDEQLDNTMN 1577
             +         R+++L+ T N
Sbjct: 894  EIEHLRSELVVREQELEQTKN 914



 Score = 85.8 bits (203), Expect = 9e-15
 Identities = 113/577 (19%), Positives = 232/577 (40%), Gaps = 28/577 (4%)

Query: 1011 INKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQ 1070
            ++K N +LK+   E  A  QK ++A +      +   ++LA+   K+E  E+ ++ ++K+
Sbjct: 29   LSKENDILKRTQAEYQAQIQKCSDALIEERETTATLTNELAECDKKIEEKEKLIEDLAKE 88

Query: 1071 LLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDX 1130
            + + K            Q+D    L+E    FE  I   E     S  + M D  + +  
Sbjct: 89   IENMKNTTS-----TASQND--SGLEEVVQEFEQKIETLE-----SENKTMKDQNSELQQ 136

Query: 1131 XXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDV 1190
                       L  +  E   +  ++  E  +   T LQ    + IQ+  L  EL    +
Sbjct: 137  QIQQYKELTDKLSTESTELQQKMENIKSEDKSAEETLLQTISDQDIQINKLKEELEQAKL 196

Query: 1191 V---NQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQRE 1247
                +++  N    K ++LN +  +L + +A  + S+S  +     +IAEL + +    E
Sbjct: 197  AANSSEQNTNAFAQKEQELNAQITDLKNQLA-AKDSLSDEIASLKAQIAELNQNNSKSSE 255

Query: 1248 ADFQ-KTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHL 1306
             + Q K E +         S   +L  +V    ++   K   +  + +   +LQ+     
Sbjct: 256  ENEQLKAESQKDASSDDKNSDLSRLKKAVVQLKKQIAQKDQEINDLKTSNMQLQNFNNET 315

Query: 1307 RNLQ-EKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQ 1365
            +N++ EKY   I + + +   ++ E                     L+ EN    ++Q Q
Sbjct: 316  QNVEIEKYKSQIIEFQKIIESLKAENAKLQTENTNTVDKLQSEIEKLKQEN---SELQNQ 372

Query: 1366 SILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTI 1425
              +  NE+      +             ++ + +    E T QL+    +  ++  +   
Sbjct: 373  --IQENEDGWNDNNNEEELQNQITELQKQLEENKKSYSEETEQLKQIIDDDSKQIEDLKQ 430

Query: 1426 TLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQK--ESEIE 1483
             L +  D   N   QL + +   + L  +       LR    +N N   T+ K  E    
Sbjct: 431  KLAEAQDHEGNSDSQLAKLQTEKQQLDKKLVDVANALRKLKTKNDNDQATISKLNEENSS 490

Query: 1484 RVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNL 1543
              K IEEL  +   + S   ++  L K L++   + ++++T  E+ + E+   N++   +
Sbjct: 491  LQKQIEELKQQTANNASYEAEIQNLKKQLQDLQIQNDDIKTENEHLQQEMFE-NNKSEEI 549

Query: 1544 QNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKEL 1580
            +   +   S++QK +S  S   Q ++++++N +NKE+
Sbjct: 550  EQQ-KKQISELQKEISSKSSEIQAKNDEIEN-LNKEI 584


>UniRef50_Q234R7 Cluster: Viral A-type inclusion protein repeat
            containing protein; n=2; Eukaryota|Rep: Viral A-type
            inclusion protein repeat containing protein - Tetrahymena
            thermophila SB210
          Length = 4039

 Score =  188 bits (457), Expect = 1e-45
 Identities = 289/1459 (19%), Positives = 637/1459 (43%), Gaps = 127/1459 (8%)

Query: 144  VTHLSNTIKEKDNALSVLQVKMKIMETTILDLQE--KI--NEKDQII-EAKNKATTXXXX 198
            +  L+  I EK+  +S L  K + +   I  ++E  K+  ++KD +I + KN+       
Sbjct: 2533 IISLNQKISEKEAQISQLNFKCESLNCQIEQIKELKKLVESQKDDVIADLKNRLQEQLTD 2592

Query: 199  XXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESK-DVRISSLEEAN 257
                         E+ K     +Q+N   ++++  + K ++  ++E++    +  L E  
Sbjct: 2593 LTSQNKNDKALKNEEEKN--IALQQNIEDLKSQVDNYKIKV-SELETQIKYELQMLNEKK 2649

Query: 258  KLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLE 317
            + LE A      E+ +L +++E+              + K   E + ++  EI+     +
Sbjct: 2650 QDLENANKRFREENKQLKEQIEKLNSNYQENKVANDSVTKLQTELN-QKINEIDHLKE-Q 2707

Query: 318  IANMTEL--TKKIELLEHLNCQIRQTNKELENKLATMGTESKA----VSSPSKKGSPLIS 371
            I N  +   T+K+EL    N Q+++T  + E K+  +  +S+     + +  +K S +I 
Sbjct: 2708 IINQDKQFKTEKMELENRFN-QMKETLTKNEQKMKQLEEKSEIELQKLQAKKQKISTIIE 2766

Query: 372  R---KSGRNTASKMKSPWSQLSSETLNQDTDKKIN-KNEIAKLEMVIQSLNKDLVDKEYV 427
                KS      K +    Q   + ++   +K IN KNE+++    +      L ++   
Sbjct: 2767 EAKAKSDEIILLKNEQIKIQAQYDNISNQLEKSINEKNELSQKIQNMSQQRDSLEEQRNQ 2826

Query: 428  ISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQH----MEGPSLIHVGT-NTEDVNEIAKVQ 482
            I E+             K  L+ Q +LE  +     ++  S   + + N   VNE +  Q
Sbjct: 2827 IKEQFNTLKETLKHTESKLELV-QKELEQAKQEKTSIQAQSSEKIKSLNDSMVNEFSS-Q 2884

Query: 483  EQLKQELNDEIKDVNV--KDLIEKLKSAEE--QITQLNDEIDAANKNMIKVKSNHKLKLK 538
             Q+ ++L D+I  ++   +   EK++  E   +I + +D+I++ N ++ +     + + +
Sbjct: 2885 NQIIEQLKDQISRLSQIQQKQQEKIQEVENISEIKKKSDQIESNNNSLQQQIFRMQEEKE 2944

Query: 539  QMQ-KTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLV-DYDSGRMIES 596
            Q+  +T D   K+ +  K  + L EE     + +  LEE+  + QL L  + D    ++S
Sbjct: 2945 QITLQTSDLNLKLEEQRKLYLNLVEENGKNKETIRSLEEKLSSEQLRLQKEVDQHEQLKS 3004

Query: 597  DVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVC 656
               +  + +EN A+ + K + +L   K +  +EL   Q++Y+    K     Q Q++Q  
Sbjct: 3005 RYEQIQLNLEN-AKIQNKELEILNQSKENRTKEL---QEQYENSMRKYE--KQKQNNQEL 3058

Query: 657  SEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQE 716
             ++K+V  E+ ++      K+    +  ++L+K          E DK  I+NK    ++E
Sbjct: 3059 -KLKTVEQEKYLNQAQIQIKDFEEQLRQMQLNKRS--------EEDKILILNKQIEELKE 3109

Query: 717  NMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKS 776
             +    K   +  E +++ +  +++ E S    + G   +I + D YI   E E+     
Sbjct: 3110 EI----KQLILKNEVLNQKITSVSNLENSDHSQKIGELQQILKND-YISKQEYEV----- 3159

Query: 777  RICR-LEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDR 835
             IC+ LE+      D     ER++    +Y Q  +K   ++  Q+     + + + D++ 
Sbjct: 3160 -ICKKLEQKNKDCLDLEQRFERESQ---NYEQNLKKIEEKFQKQQQLTEQKYSEMQDNNE 3215

Query: 836  VVEKQLLE-IEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESEST 894
            +  K+ LE ++ ++++L ++ Q+  EE +        +Q+ +N L EK            
Sbjct: 3216 IQHKKSLEQLKEKHEKLMQQQQVSFEEEKE------GLQKKFNLLKEK------------ 3257

Query: 895  KYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNI 954
                 L + E  + ++  E Q +I Q K +I+    E+N Q  +  +  K L E  ++N+
Sbjct: 3258 -----LTNSEDQISQVEQEKQKIISQNKSKIQ----EYNEQQLAQEQIIKNLQESIKQNL 3308

Query: 955  EYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKL 1014
            + +T+ E  +++ +  ++N    +++  K  ++ + K +++ Q ++    ++ IN +N+ 
Sbjct: 3309 QKMTEQEELIKKQQKQVKNSEEIIDQ-QKQQIDELQKSLKQTQAENEKQMQEQINNLNQK 3367

Query: 1015 NALLKQK----DEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQ 1070
             ++ + +     +++I + QK+        S+V+DYE ++     +L+ +  E+    +Q
Sbjct: 3368 ISIKESECTNLQQQLIQIEQKMKEEN---QSLVADYEKQIKTLKDELDLITREVTAQKEQ 3424

Query: 1071 LLDSKQH----NEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDAN 1126
                ++       +L  L +E  ++I ++++ K   ++ I +T    I      +S++  
Sbjct: 3425 EKSQQEQINKLESQLNELTKENQEKIAQIEQIK-DEDLKIIQTLKNEIQELESSISNNKQ 3483

Query: 1127 NVDXXXXXXXXXXXXLKVQEEEEF---IQERSVLQEQSAKLNTELQECYTKIIQLETLNT 1183
             ++            LK   E++      E   LQE  A L  +++E   +  + E +N 
Sbjct: 3484 QIETSTNQYQSELTKLKEDSEQKLELKSAEIQKLQENIAILTKQIEEEQKQ--KTELINQ 3541

Query: 1184 ELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAEL--RSSISSAVDQRGFEIAELWKQ 1241
              +      +E  N   S   Q+    + L+ +  EL  +  I S +++R  E +EL  +
Sbjct: 3542 HQSEIQNKEKELANFQNSNSIQIKNLEEQLIQSQKELDEKKQILSQLEERQKE-SELSIK 3600

Query: 1242 HLAQREADFQK-TEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQN-KL 1299
             L ++ +  Q+   H    Q +  E K   LL  +Q   ++ ++    M+    L    L
Sbjct: 3601 QLQEKLSQKQEEVVHLQTTQNATKEEKISILLSQIQELEKQLSDSKSEMKNKNQLSEASL 3660

Query: 1300 QDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSY 1359
             + +E +  L++KY+++     +L SE++                       ++ E  + 
Sbjct: 3661 NEAKEKITILEQKYSNLQKNYSLLESELKQALEKSKKEKDELIQTHQQELSQVQKEFITL 3720

Query: 1360 KQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQK 1419
                E++ +++ E+++Q+K+ S            ++   + K  +   QL+LK+SEI Q 
Sbjct: 3721 NSQIEKNKIDMIEKDSQIKRISIEHDETQK----QLESLKQKYQQSLEQLQLKESEITQL 3776

Query: 1420 THEYTITLTQRNDEFENVRQ----QLVEYEKRIEDLTYEKESELAILR---LKMHENANH 1472
              +  +   +   + E +++    Q+ +  K  ++   + +SEL        K+ +    
Sbjct: 3777 KKQMQLDKYEALSQIEQLKREQNNQIDQINKEYQEKIQKLQSELQKGNDEAQKLRQQIES 3836

Query: 1473 YETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIE 1532
             + + + S  E   LI+++  +  E+V  N+ +AEL   L +   + NE+   +   E +
Sbjct: 3837 LQAISQGSSNEMQNLIQKMKEQQEENVKSNQSIAELQSQLVKSNLQANELNQKISKLESK 3896

Query: 1533 IVTLNDEITNLQNMVRASS 1551
            + +  + I  L+     SS
Sbjct: 3897 LQSTENFIDALKKQENQSS 3915



 Score =  163 bits (395), Expect = 5e-38
 Identities = 264/1450 (18%), Positives = 647/1450 (44%), Gaps = 141/1450 (9%)

Query: 162  QVKMKIMETTILDL-QEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXE------DT 214
            Q +++ + + IL + QEK +   QI ++KN+                    +      + 
Sbjct: 2122 QTQIESLNSKILQIEQEKTDAIKQIEQSKNQEIASNLLMTNQKISNLEEQFKQKLADFEN 2181

Query: 215  KQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEA-NKLLEAARFEISLEHSK 273
             Q   K Q+  I  E  + +++     D+E ++ +I  LE+A  KL+E      + +  +
Sbjct: 2182 IQNSQKKQKKKIQKEESYLNQESG--NDLEDQERQIKQLEDAYQKLMEQHERNQTEQQQE 2239

Query: 274  LAQELEQXXXXXXXXXXXXXXLAKQSIEPSC---EEKTEIEEKGSLEIANMTELTKKIEL 330
            + ++ +               L ++  E S    E + + E+    E+    E+   I+ 
Sbjct: 2240 MKRQYDNIEEQIRENLQKQMQLMQEKYERSMVIYENQIKEEQSKYRELRQSHEIA--IKN 2297

Query: 331  LEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLS 390
            L  L+   ++T  +  N+   +      +     K   L  +          +   S++ 
Sbjct: 2298 LNDLHFSQQKTVLDQSNEKVDL------LKQQLSKYEELFQKSVEEQKQQFERISQSEIQ 2351

Query: 391  SETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIA 450
               +N +++ K+   +I  L+  +    + + D E ++ +K+            K   + 
Sbjct: 2352 KGIINVESEYKL---QIQSLQDKLSHAMEKMQDCEQLLKKKEEQEKNLIEEYDKKIVQVL 2408

Query: 451  QLQLEH-QQHMEGPSLIHVGTNTEDVN---EIAKVQEQLKQELNDEIKDVNVKDLIEK-L 505
            Q  +   Q+ +   S  ++   ++  N   EI ++QE +KQ+   +I++ N+KDLI++  
Sbjct: 2409 QNDIACLQESLINQSKQNMKELSQIQNAQKEIGEIQETIKQQ---KIQENNLKDLIQQHF 2465

Query: 506  KSAEEQITQLNDEIDAANKNMIKVKSN--HK--LKLKQMQKTIDN----FSKVSDSNKEI 557
             + +  +  + DE      + ++ K N  H+  L L + +  ++N     S+ ++ N+++
Sbjct: 2466 SNIQTSLQAVKDESIKNQSHQLQEKCNEIHQKILSLLESKHLLENKHAVASEEAEENQKL 2525

Query: 558  VRLTEELH-HLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAI 616
             + ++E+   L+QK++E E +   L       +              ++E + E +    
Sbjct: 2526 AKESKEMIISLNQKISEKEAQISQLNFKCESLNC-------------QIEQIKELK---- 2568

Query: 617  SLLESQKFDLVQELHILQQKYDEVEDKLADI-SQLQSDQVCS--EIKSVHLEEQIDALSA 673
             L+ESQK D++ +L       + ++++L D+ SQ ++D+     E K++ L++ I+ L +
Sbjct: 2569 KLVESQKDDVIADLK------NRLQEQLTDLTSQNKNDKALKNEEEKNIALQQNIEDLKS 2622

Query: 674  SKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKIS 733
                  + +  L+    Q+   ++ L   K+D+ N  + + +EN  L +++EK+++    
Sbjct: 2623 QVDNYKIKVSELET---QIKYELQMLNEKKQDLENANKRFREENKQLKEQIEKLNSNYQE 2679

Query: 734  ELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKS-------RICRLEESIA 786
                K+ ++  +K+QT+  ++ KI E D   E I ++  ++K+       R  +++E++ 
Sbjct: 2680 N---KVANDSVTKLQTE--LNQKINEIDHLKEQIINQDKQFKTEKMELENRFNQMKETLT 2734

Query: 787  VMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRV-VEKQLLEIE 845
              E +   LE K++     LQ K++  S   I+E +  +   +L+ ++++ ++ Q   I 
Sbjct: 2735 KNEQKMKQLEEKSEIELQKLQAKKQKISTI-IEEAKAKSDEIILLKNEQIKIQAQYDNIS 2793

Query: 846  HE-NKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKY-QTQLRDL 903
            ++  K + +KN+ L ++ QN+      +++  N + E+ N       E+ K+ +++L  +
Sbjct: 2794 NQLEKSINEKNE-LSQKIQNMSQQRDSLEEQRNQIKEQFNTL----KETLKHTESKLELV 2848

Query: 904  ESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQ 963
            +  L++   E  ++  Q  ++I+ L    N  + +    +  + E+ +  I  ++Q++ +
Sbjct: 2849 QKELEQAKQEKTSIQAQSSEKIKSL----NDSMVNEFSSQNQIIEQLKDQISRLSQIQQK 2904

Query: 964  LQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDE 1023
             QE    +EN++   ++ ++  +E  +  +Q+Q  +  +  EQ   + + LN  L+++ +
Sbjct: 2905 QQEKIQEVENISEIKKKSDQ--IESNNNSLQQQIFRMQEEKEQITLQTSDLNLKLEEQRK 2962

Query: 1024 ---EIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEE 1080
                ++  N K      S    +S  + +L +   + E ++   +++   L ++K  N+E
Sbjct: 2963 LYLNLVEENGKNKETIRSLEEKLSSEQLRLQKEVDQHEQLKSRYEQIQLNLENAKIQNKE 3022

Query: 1081 LQILVREQDDQIKELKE----TKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXX 1136
            L+IL + ++++ KEL+E    +   +E      + + + +  +    +   +        
Sbjct: 3023 LEILNQSKENRTKELQEQYENSMRKYEKQKQNNQELKLKTVEQEKYLNQAQIQIKDFEEQ 3082

Query: 1137 XXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQI 1196
                 L  + EE+ I    +L +Q  +L  E+++    I++ E LN ++T    +     
Sbjct: 3083 LRQMQLNKRSEEDKIL---ILNKQIEELKEEIKQL---ILKNEVLNQKITSVSNLENSDH 3136

Query: 1197 NQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHE 1256
            +Q   +L+Q+  +ND +     E+        ++   ++ + +++     E + +K E +
Sbjct: 3137 SQKIGELQQI-LKNDYISKQEYEVICKKLEQKNKDCLDLEQRFERESQNYEQNLKKIEEK 3195

Query: 1257 LRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKY--- 1313
             + Q    E KY ++ D+ +   ++   ++    +    Q ++  +EE    LQ+K+   
Sbjct: 3196 FQKQQQLTEQKYSEMQDNNEIQHKKSLEQLKEKHEKLMQQQQVSFEEEK-EGLQKKFNLL 3254

Query: 1314 ADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQE---QSILNI 1370
             + +   E   S++E EK                       + Q  K +QE   Q++  +
Sbjct: 3255 KEKLTNSEDQISQVEQEKQKIISQNKSKIQEYNEQQL---AQEQIIKNLQESIKQNLQKM 3311

Query: 1371 NEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQR 1430
             E+   +KK               ++  + ++ EL   L+   +E  ++  E    L Q+
Sbjct: 3312 TEQEELIKKQQKQVKNSEEI----IDQQKQQIDELQKSLKQTQAENEKQMQEQINNLNQK 3367

Query: 1431 ----NDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVK 1486
                  E  N++QQL++ E+++++   E +S +A       +     +T++ E ++   +
Sbjct: 3368 ISIKESECTNLQQQLIQIEQKMKE---ENQSLVA-------DYEKQIKTLKDELDLITRE 3417

Query: 1487 LIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIV-TLNDEITNLQN 1545
            +  +   + ++   +NK  ++LN+  +E   K  +++  +++++++I+ TL +EI  L++
Sbjct: 3418 VTAQKEQEKSQQEQINKLESQLNELTKENQEKIAQIEQ-IKDEDLKIIQTLKNEIQELES 3476

Query: 1546 MVRASSSKIQ 1555
             +  +  +I+
Sbjct: 3477 SISNNKQQIE 3486



 Score =  160 bits (389), Expect = 3e-37
 Identities = 293/1460 (20%), Positives = 632/1460 (43%), Gaps = 137/1460 (9%)

Query: 149  NTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXX 208
            N IKE+ +    L+   +I    + DL    +++  +++  N+                 
Sbjct: 2275 NQIKEEQSKYRELRQSHEIAIKNLNDLH--FSQQKTVLDQSNEKVDLLKQQLSKYEELFQ 2332

Query: 209  XXXEDTKQQM-----TKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAA 263
               E+ KQQ      +++Q+  I +E+E+K + Q L   +     ++   E+  K  E  
Sbjct: 2333 KSVEEQKQQFERISQSEIQKGIINVESEYKLQIQSLQDKLSHAMEKMQDCEQLLKKKEEQ 2392

Query: 264  RFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTE 323
               +  E+ K   ++ Q              L  QS + + +E ++I+     EI  + E
Sbjct: 2393 EKNLIEEYDKKIVQVLQNDIACLQES-----LINQS-KQNMKELSQIQN-AQKEIGEIQE 2445

Query: 324  LTKKIELLEH-LNCQIRQTNKELENKLATMGTES-KAVSSPSKKGSPLISRKSGRNTASK 381
              K+ ++ E+ L   I+Q    ++  L  +  ES K  S   ++    I +K      SK
Sbjct: 2446 TIKQQKIQENNLKDLIQQHFSNIQTSLQAVKDESIKNQSHQLQEKCNEIHQKILSLLESK 2505

Query: 382  --MKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXX 439
              +++  +  S E    + ++K+ K      EM+I SLN+ + +KE  IS+ +       
Sbjct: 2506 HLLENKHAVASEEA---EENQKLAKES---KEMII-SLNQKISEKEAQISQLNFKC---- 2554

Query: 440  XXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVK 499
                  ++L  Q++    Q  E   L+   +  +DV  IA ++ +L+++L D +   N  
Sbjct: 2555 ------ESLNCQIE----QIKELKKLVE--SQKDDV--IADLKNRLQEQLTD-LTSQNKN 2599

Query: 500  DLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTID-NFSKVSDSNKEIV 558
            D  + LK+ EE+   L   I+     +     N+K+K+ +++  I      +++  +++ 
Sbjct: 2600 D--KALKNEEEKNIALQQNIEDLKSQV----DNYKIKVSELETQIKYELQMLNEKKQDLE 2653

Query: 559  RLTEELHHLSQKVAE-LEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAIS 617
               +     ++++ E +E+   N Q + V  DS   +++++ +K+ E+++L E  +    
Sbjct: 2654 NANKRFREENKQLKEQIEKLNSNYQENKVANDSVTKLQTELNQKINEIDHLKEQIINQDK 2713

Query: 618  LLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKE 677
              +++K +L    + +++   + E K+  + +       SEI       ++  L A K++
Sbjct: 2714 QFKTEKMELENRFNQMKETLTKNEQKMKQLEEK------SEI-------ELQKLQAKKQK 2760

Query: 678  LALVIENLKLDKEQLYGTIKD---LENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISE 734
            ++ +IE  K   +++     +   ++   ++I N+L+  I E  +L+ K++ MS ++ S 
Sbjct: 2761 ISTIIEEAKAKSDEIILLKNEQIKIQAQYDNISNQLEKSINEKNELSQKIQNMSQQRDSL 2820

Query: 735  LLAKINHEEQSKIQTQFG-IDAKIQERDLYIENIESELSKYKSRICRLE----ESIAVME 789
                   E++++I+ QF  +   ++  +  +E ++ EL + K     ++    E I  + 
Sbjct: 2821 ------EEQRNQIKEQFNTLKETLKHTESKLELVQKELEQAKQEKTSIQAQSSEKIKSLN 2874

Query: 790  DRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENK 849
            D   +     +Q+   L+++    S+   ++ E +  +  + +    ++K+  +IE  N 
Sbjct: 2875 DSMVNEFSSQNQIIEQLKDQISRLSQIQQKQQEKIQEVENISE----IKKKSDQIESNNN 2930

Query: 850  ELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDL-AESESTKYQTQLRDLESNLK 908
             LQ++   + EE + + +  SD+    N  +E+  +  L    E+ K +  +R LE  L 
Sbjct: 2931 SLQQQIFRMQEEKEQITLQTSDL----NLKLEEQRKLYLNLVEENGKNKETIRSLEEKLS 2986

Query: 909  RITHEHQTLIVQK---KKEIEDLEIEF-NTQIESAIRDKKVLNEKYEKNI-EYVTQLEAQ 963
                  Q  + Q    K   E +++   N +I++  ++ ++LN+  E    E   Q E  
Sbjct: 2987 SEQLRLQKEVDQHEQLKSRYEQIQLNLENAKIQN--KELEILNQSKENRTKELQEQYENS 3044

Query: 964  LQEY---KNNIENLNMNVEE----LNKMNLELIDKHVQKQQTQSPDYTEQ-YINEINKLN 1015
            +++Y   K N + L +   E    LN+  +++ D   Q +Q Q    +E+  I  +NK  
Sbjct: 3045 MRKYEKQKQNNQELKLKTVEQEKYLNQAQIQIKDFEEQLRQMQLNKRSEEDKILILNKQI 3104

Query: 1016 ALLKQKDEEIIALNQKINNAQVSYMSMV-SDYESKLAQFTTKLEN---MEEEMQRVSKQL 1071
              LK++ +++I  N+ +N    S  ++  SD+  K+ +    L+N    ++E + + K+L
Sbjct: 3105 EELKEEIKQLILKNEVLNQKITSVSNLENSDHSQKIGELQQILKNDYISKQEYEVICKKL 3164

Query: 1072 LDSKQHNEEL-QILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDX 1130
                +   +L Q   RE  +  + LK+ +  F+     TE          M D+ N +  
Sbjct: 3165 EQKNKDCLDLEQRFERESQNYEQNLKKIEEKFQKQQQLTE-----QKYSEMQDN-NEIQH 3218

Query: 1131 XXXXXXXXXXXLKVQEEEE--FIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGH 1188
                        K+ ++++  F +E+  LQ++   L  +L     +I Q+E    ++   
Sbjct: 3219 KKSLEQLKEKHEKLMQQQQVSFEEEKEGLQKKFNLLKEKLTNSEDQISQVEQEKQKIISQ 3278

Query: 1189 DVVNQEQINQLKSKLEQL--NTEND--NLLSTVAELRSSISSAVDQ--RGFEIAELWKQH 1242
            +    ++ N+ +   EQ+  N +      L  + E    I     Q     EI +  KQ 
Sbjct: 3279 NKSKIQEYNEQQLAQEQIIKNLQESIKQNLQKMTEQEELIKKQQKQVKNSEEIIDQQKQQ 3338

Query: 1243 LAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNK--LQ 1300
            + + +   ++T+ E   Q+    +   Q +   +S       +++ +EQ    +N+  + 
Sbjct: 3339 IDELQKSLKQTQAENEKQMQEQINNLNQKISIKESECTNLQQQLIQIEQKMKEENQSLVA 3398

Query: 1301 DKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYK 1360
            D E+ ++ L+++  D+I +    + E E  +                   +   + +  K
Sbjct: 3399 DYEKQIKTLKDEL-DLITREVTAQKEQEKSQQEQINKLESQLNELTKENQEKIAQIEQIK 3457

Query: 1361 QMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQ-LELKDSEIYQK 1419
                + I  +  E  +L+ S             +      K+ E + Q LELK +EI QK
Sbjct: 3458 DEDLKIIQTLKNEIQELESSISNNKQQIETSTNQYQSELTKLKEDSEQKLELKSAEI-QK 3516

Query: 1420 THEYTITLTQRNDEFENVRQQLV-EYEKRIEDLTYEKESELAILRLKMHENANHYET--M 1476
              E    LT++ +E +  + +L+ +++  I++    KE ELA  +        + E   +
Sbjct: 3517 LQENIAILTKQIEEEQKQKTELINQHQSEIQN----KEKELANFQNSNSIQIKNLEEQLI 3572

Query: 1477 QKESEI-ERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVT 1535
            Q + E+ E+ +++ +L  +  ES    KQ+ E     +EEV      Q A + ++I I  
Sbjct: 3573 QSQKELDEKKQILSQLEERQKESELSIKQLQEKLSQKQEEVVHLQTTQNATKEEKISI-- 3630

Query: 1536 LNDEITNLQNMVRASSSKIQ 1555
            L  +I  L+  +  S S+++
Sbjct: 3631 LLSQIQELEKQLSDSKSEMK 3650



 Score =  145 bits (351), Expect = 1e-32
 Identities = 271/1435 (18%), Positives = 619/1435 (43%), Gaps = 118/1435 (8%)

Query: 176  QEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDE 235
            Q +++EK +++++ +                        +++  K+ E  +  + E+K++
Sbjct: 1535 QNELSEKQKLLDSLSDQLKIDQELLMKERQKLQEETVQFEEKQNKLTEEILKQQQEYKEK 1594

Query: 236  KQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXL 295
              + L+D +     +  L       E  + ++SL  S + ++ EQ              L
Sbjct: 1595 YDKYLQDFQEYQNLMKQLSIQKVAQEELQNQLSLRSSLIKEQQEQLEKHLLNLTEQQQQL 1654

Query: 296  AKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTE 355
             K  I    ++K   E+K  L      +  K+ E ++    QI+Q  +E++     +  E
Sbjct: 1655 -KDIIVQFDKKK---EDKNQLIEYFQAQCEKQEEEIK----QIKQKYEEIQKLSQDINLE 1706

Query: 356  SKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQ 415
             + V     +       ++ +N    ++S +    SET N       NK E+  L + +Q
Sbjct: 1707 KEIVKREHAQ------CQNSQNQIDIVRSDYQNKISETNNS------NKKELEALNLALQ 1754

Query: 416  SLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDV 475
              N+ + +++ +I   +              ++ +    E +Q +E  +   +    +  
Sbjct: 1755 EKNERIAEQKEMIKSLNQTIKSLESKIENL-SIKSDNYDETKQKLEQKNEELILLKQQVA 1813

Query: 476  NEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKL 535
             E  + Q  L Q LND +K ++ K+        EEQ  Q  +E+    +N IK +S    
Sbjct: 1814 QEQKEKQIFLNQ-LND-LKSIDEKNQ-NNFTKKEEQYQQKINELQLQFQNEIKTESAQIN 1870

Query: 536  KLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIE 595
            KL+   +T     K+ +  ++    ++++    Q     EE+   LQ+ L    + R  E
Sbjct: 1871 KLRDEYQT-----KIDEMKEKYFESSQKMKEAEQISQFKEEQIKQLQISLESEQNNRKEE 1925

Query: 596  SDVYKKMIEMENLA-ETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQ 654
                +K  E +  A  + LK     +++K   + E H + Q    + +K  D  QL+++ 
Sbjct: 1926 KQTLQKYFEEQFAAIISHLKE----DNEKLKQLHENHSVVQ----LNEKEQDFIQLKTNY 1977

Query: 655  VCSEIKSVHLEEQI-DALSASKKELALVIENLKLDKEQLYGTIKDLE-NDKEDIMNKLQN 712
               E ++  L+  + + ++  K +  L + NL +   QL+ T   L  ++K+++  ++Q 
Sbjct: 1978 ALIEQQADILKSLMQNEIAQKKNQSQLNLSNLTV--LQLFETFIQLNASEKQNLEEEIQK 2035

Query: 713  YIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELS 772
                 +  T+K  K     ++E  AK   +  ++I        K   +   I  +E + +
Sbjct: 2036 L---KISHTEKDSKYLL--LTEDFAKYKDQIATEISNLKEKSHKNDYQTELINQLEQKNA 2090

Query: 773  KYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQ-EDELVNRL-AVL 830
            K K +  +L+E +   E++   L+ +  +L    Q + ++ +   +Q E E  + +  + 
Sbjct: 2091 KVKQKCSQLQEKLQETENQ---LKSQIFELEKQHQTQIESLNSKILQIEQEKTDAIKQIE 2147

Query: 831  MDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAE 890
               ++ +   LL    +   L+++ +  L + +N+Q   S  +Q      E++     + 
Sbjct: 2148 QSKNQEIASNLLMTNQKISNLEEQFKQKLADFENIQ--NSQKKQKKKIQKEESYLNQESG 2205

Query: 891  SESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQI-ESAIRDKKVLNEK 949
            ++    + Q++ LE   +++  +H+    ++++E++        QI E+  +  +++ EK
Sbjct: 2206 NDLEDQERQIKQLEDAYQKLMEQHERNQTEQQQEMKRQYDNIEEQIRENLQKQMQLMQEK 2265

Query: 950  YEKN-IEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYI 1008
            YE++ + Y  Q++ +  +Y+   ++  + ++ LN ++     K V  Q  +  D  +Q  
Sbjct: 2266 YERSMVIYENQIKEEQSKYRELRQSHEIAIKNLNDLHFSQ-QKTVLDQSNEKVDLLKQ-- 2322

Query: 1009 NEINKLNALLKQKDEEIIALNQKINNAQV--SYMSMVSDYESKLAQFTTKLENMEEEMQR 1066
             +++K   L ++  EE     ++I+ +++    +++ S+Y+ ++     KL +  E+MQ 
Sbjct: 2323 -QLSKYEELFQKSVEEQKQQFERISQSEIQKGIINVESEYKLQIQSLQDKLSHAMEKMQD 2381

Query: 1067 VSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDAN 1126
              +QLL  K+  E  + L+ E D +I ++       + +I   +  +I+ + + M  + +
Sbjct: 2382 -CEQLLKKKEEQE--KNLIEEYDKKIVQV------LQNDIACLQESLINQSKQNMK-ELS 2431

Query: 1127 NVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELT 1186
             +             +K Q+ +E    + ++Q+  + + T LQ      ++ E++  +  
Sbjct: 2432 QIQNAQKEIGEIQETIKQQKIQE-NNLKDLIQQHFSNIQTSLQ-----AVKDESIKNQ-- 2483

Query: 1187 GHDVVNQEQINQLKSKLEQLNTENDNLLS---TVAELRSSISSAVDQRGFEIAELWKQHL 1243
             H +  QE+ N++  K+  L  E+ +LL     VA   +  +  + +   E+     Q +
Sbjct: 2484 SHQL--QEKCNEIHQKILSL-LESKHLLENKHAVASEEAEENQKLAKESKEMIISLNQKI 2540

Query: 1244 AQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVT--MEQVTSLQNKLQD 1301
            +++EA   +   +    L+    + ++L   V+S   +    +     EQ+T L ++   
Sbjct: 2541 SEKEAQISQLNFKCE-SLNCQIEQIKELKKLVESQKDDVIADLKNRLQEQLTDLTSQ-NK 2598

Query: 1302 KEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQ 1361
             ++ L+N +EK   +   IE L+S++++ K+                  +L+  N+  KQ
Sbjct: 2599 NDKALKNEEEKNIALQQNIEDLKSQVDNYKI-------KVSELETQIKYELQMLNEK-KQ 2650

Query: 1362 MQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKV-LELTHQLELKD---SEIY 1417
              E +     EEN QLK+                ND+  K+  EL  ++   D    +I 
Sbjct: 2651 DLENANKRFREENKQLKEQIEKLNSNYQENKV-ANDSVTKLQTELNQKINEIDHLKEQII 2709

Query: 1418 QKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQ 1477
             +  ++     +  + F  +++ L + E++++ L  + E EL  L+ K  + +   E  +
Sbjct: 2710 NQDKQFKTEKMELENRFNQMKETLTKNEQKMKQLEEKSEIELQKLQAKKQKISTIIEEAK 2769

Query: 1478 KESEIERVKLIEELNVKIT---ESVS--LNKQVAELNKALEEEVAKTNEMQTALENQEIE 1532
             +S  + + L++   +KI    +++S  L K + E N+ L +++   ++ + +LE Q  +
Sbjct: 2770 AKS--DEIILLKNEQIKIQAQYDNISNQLEKSINEKNE-LSQKIQNMSQQRDSLEEQRNQ 2826

Query: 1533 IVTLNDEITNLQNMVRASSSK---IQKHVSFASDTKQGRDEQLDNTMNKELLDAV 1584
            I    ++   L+  ++ + SK   +QK +  A   K     Q    + K L D++
Sbjct: 2827 I---KEQFNTLKETLKHTESKLELVQKELEQAKQEKTSIQAQSSEKI-KSLNDSM 2877



 Score =  141 bits (342), Expect = 1e-31
 Identities = 279/1389 (20%), Positives = 593/1389 (42%), Gaps = 122/1389 (8%)

Query: 230  AEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXX 289
            A++KD+    + +++ K  +     E    LE    ++  + S+L ++L++         
Sbjct: 2055 AKYKDQIATEISNLKEKSHKNDYQTELINQLEQKNAKVKQKCSQLQEKLQETENQ----- 2109

Query: 290  XXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKL 349
                 L  Q  E   + +T+IE   S  +    E T  I+ +E      +  N+E+ + L
Sbjct: 2110 -----LKSQIFELEKQHQTQIESLNSKILQIEQEKTDAIKQIE------QSKNQEIASNL 2158

Query: 350  ATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDT--DKKINKNEI 407
              + T  K  +   +    L   ++ +N+  K K    Q     LNQ++  D +  + +I
Sbjct: 2159 --LMTNQKISNLEEQFKQKLADFENIQNSQKKQKKK-IQKEESYLNQESGNDLEDQERQI 2215

Query: 408  AKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIH 467
             +LE   Q L +   ++     +++            ++ L  Q+QL  +++ E   +I+
Sbjct: 2216 KQLEDAYQKLMEQH-ERNQTEQQQEMKRQYDNIEEQIRENLQKQMQLMQEKY-ERSMVIY 2273

Query: 468  VGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEI----DAAN 523
                 E+ ++  ++++  +  + + + D++       L  + E++  L  ++    +   
Sbjct: 2274 ENQIKEEQSKYRELRQSHEIAIKN-LNDLHFSQQKTVLDQSNEKVDLLKQQLSKYEELFQ 2332

Query: 524  KNMIKVKSN-HKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEE---EKG 579
            K++ + K    ++   ++QK I N    S+   +I  L ++L H  +K+ + E+   +K 
Sbjct: 2333 KSVEEQKQQFERISQSEIQKGIINVE--SEYKLQIQSLQDKLSHAMEKMQDCEQLLKKKE 2390

Query: 580  NLQLHLVD-YDSG--RMIESDVYKKMIEMENLAETRLKAISLLESQKFDL--VQELHILQ 634
              + +L++ YD    +++++D+      + N ++  +K +S +++ + ++  +QE  I Q
Sbjct: 2391 EQEKNLIEEYDKKIVQVLQNDIACLQESLINQSKQNMKELSQIQNAQKEIGEIQET-IKQ 2449

Query: 635  QKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYG 694
            QK  E  + L D+ Q     + + +++V  +E I   S   +E             +++ 
Sbjct: 2450 QKIQE--NNLKDLIQQHFSNIQTSLQAVK-DESIKNQSHQLQEKC----------NEIHQ 2496

Query: 695  TIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGID 754
             I  L   K  + NK      E  +   KL K S E I  L  KI+ +E    Q  F   
Sbjct: 2497 KILSLLESKHLLENK-HAVASEEAEENQKLAKESKEMIISLNQKISEKEAQISQLNF--- 2552

Query: 755  AKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQ-KAY 813
             K +  +  IE I+ EL K      + ++ IA +++R    E+  D       +K  K  
Sbjct: 2553 -KCESLNCQIEQIK-ELKKLVES--QKDDVIADLKNRLQ--EQLTDLTSQNKNDKALKNE 2606

Query: 814  SEYTIQEDELVNRLAVLMDHDRVVEKQL-LEIEHENKELQKKNQILLEENQNLQISLSDM 872
             E  I   + +  L   +D+ ++   +L  +I++E + L +K Q L   N+  +     +
Sbjct: 2607 EEKNIALQQNIEDLKSQVDNYKIKVSELETQIKYELQMLNEKKQDLENANKRFREENKQL 2666

Query: 873  QQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKK-EIEDLEIE 931
            ++    L        +A    TK QT   +L   +  I H  + +I Q K+ + E +E+E
Sbjct: 2667 KEQIEKLNSNYQENKVANDSVTKLQT---ELNQKINEIDHLKEQIINQDKQFKTEKMELE 2723

Query: 932  --FNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELI 989
              FN   E+  ++++ + +  EK+   + +L+A+ Q+    IE      +E+  +  E I
Sbjct: 2724 NRFNQMKETLTKNEQKMKQLEEKSEIELQKLQAKKQKISTIIEEAKAKSDEIILLKNEQI 2783

Query: 990  DKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSM---VSDY 1046
               +Q Q     +  E+ INE N+L+  ++   ++  +L ++ N  +  + ++   +   
Sbjct: 2784 --KIQAQYDNISNQLEKSINEKNELSQKIQNMSQQRDSLEEQRNQIKEQFNTLKETLKHT 2841

Query: 1047 ESKLAQFTTKLENMEEEMQRVSKQLLDS-KQHNEELQILVREQDDQIKELKETKLTFEMN 1105
            ESKL     +LE  ++E   +  Q  +  K  N+ +      Q+  I++LK+        
Sbjct: 2842 ESKLELVQKELEQAKQEKTSIQAQSSEKIKSLNDSMVNEFSSQNQIIEQLKDQISRLSQI 2901

Query: 1106 IPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXL-KVQEEEEFI----QERSVLQEQ 1160
              K +  I    +E +S+     D            + ++QEE+E I     + ++  E+
Sbjct: 2902 QQKQQEKI--QEVENISEIKKKSDQIESNNNSLQQQIFRMQEEKEQITLQTSDLNLKLEE 2959

Query: 1161 SAKLNTELQECYTKIIQ-LETLNTELTGHDVVNQEQIN---QLKSKLE--QLNTENDNLL 1214
              KL   L E   K  + + +L  +L+   +  Q++++   QLKS+ E  QLN EN  + 
Sbjct: 2960 QRKLYLNLVEENGKNKETIRSLEEKLSSEQLRLQKEVDQHEQLKSRYEQIQLNLENAKIQ 3019

Query: 1215 STVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDS 1274
            +   E+   ++ + + R  E+ E ++  + + E   Q  + EL+++ +  + KY   L+ 
Sbjct: 3020 NKELEI---LNQSKENRTKELQEQYENSMRKYEKQKQNNQ-ELKLK-TVEQEKY---LNQ 3071

Query: 1275 VQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIE--ILRSEIEDEKV 1332
             Q   ++        EQ+  +Q   + +E+ +  L ++  ++  +I+  IL++E+ ++K+
Sbjct: 3072 AQIQIKD------FEEQLRQMQLNKRSEEDKILILNKQIEELKEEIKQLILKNEVLNQKI 3125

Query: 1333 AFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSIL--NINEENAQLKKSSXXXXXXXXX 1390
                                  +N  Y   QE  ++   + ++N                
Sbjct: 3126 TSVSNLENSDHSQKIGELQQILKN-DYISKQEYEVICKKLEQKNKDCLDLEQRFERESQN 3184

Query: 1391 XXXRVNDAEAKVLELTHQLELKDSEIYQKTH-EYTITLTQRNDEFEN-VRQQLVEYEKRI 1448
                +   E K  +     E K SE+      ++  +L Q  ++ E  ++QQ V +E+  
Sbjct: 3185 YEQNLKKIEEKFQKQQQLTEQKYSEMQDNNEIQHKKSLEQLKEKHEKLMQQQQVSFEEEK 3244

Query: 1449 EDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAEL 1508
            E L  +K+  L      + E   + E    + E E+ K+I +   KI E         ++
Sbjct: 3245 EGL--QKKFNL------LKEKLTNSEDQISQVEQEKQKIISQNKSKIQEYNEQQLAQEQI 3296

Query: 1509 NKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGR 1568
             K L+E + K N +Q   E +E+ I     ++ N + ++     +I +       T+   
Sbjct: 3297 IKNLQESI-KQN-LQKMTEQEEL-IKKQQKQVKNSEEIIDQQKQQIDELQKSLKQTQAEN 3353

Query: 1569 DEQLDNTMN 1577
            ++Q+   +N
Sbjct: 3354 EKQMQEQIN 3362



 Score =  137 bits (331), Expect = 3e-30
 Identities = 247/1264 (19%), Positives = 538/1264 (42%), Gaps = 101/1264 (7%)

Query: 337  QIRQTNKELENKLATMGTESKAVSSPSKKGSPLI--SRKSGRNTASKMKSPWSQLSSETL 394
            Q ++  K  +N+L+       ++S   K    L+   R+  +    + +   ++L+ E L
Sbjct: 1526 QCQENIKLAQNELSEKQKLLDSLSDQLKIDQELLMKERQKLQEETVQFEEKQNKLTEEIL 1585

Query: 395  NQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQ--L 452
             Q  + K   ++  +     Q+L K L  ++    E              +   + +  L
Sbjct: 1586 KQQQEYKEKYDKYLQDFQEYQNLMKQLSIQKVAQEELQNQLSLRSSLIKEQQEQLEKHLL 1645

Query: 453  QLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQI 512
             L  QQ      ++      ED N++ +  +   ++  +EIK +         K   E+I
Sbjct: 1646 NLTEQQQQLKDIIVQFDKKKEDKNQLIEYFQAQCEKQEEEIKQI---------KQKYEEI 1696

Query: 513  TQLNDEIDAANKNMIKVKSNHKLKLKQMQKTI---DNFSKVSDSN----KEIVRLTEELH 565
             +L+ +I+   K ++K + + + +  Q Q  I   D  +K+S++N    KE+  L   L 
Sbjct: 1697 QKLSQDINL-EKEIVK-REHAQCQNSQNQIDIVRSDYQNKISETNNSNKKELEALNLALQ 1754

Query: 566  HLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFD 625
              ++++AE +E   +L   +      + +ES +    I+ +N  ET+ K    LE +  +
Sbjct: 1755 EKNERIAEQKEMIKSLNQTI------KSLESKIENLSIKSDNYDETKQK----LEQKNEE 1804

Query: 626  LVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIEN- 684
            L+    + QQ   E ++K   ++QL   +   E    +  ++ +       EL L  +N 
Sbjct: 1805 LIL---LKQQVAQEQKEKQIFLNQLNDLKSIDEKNQNNFTKKEEQYQQKINELQLQFQNE 1861

Query: 685  LKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQ 744
            +K +  Q+   ++D    K D M +      + M   +++ +   E+I +L   +  E+ 
Sbjct: 1862 IKTESAQI-NKLRDEYQTKIDEMKEKYFESSQKMKEAEQISQFKEEQIKQLQISLESEQN 1920

Query: 745  SKIQTQFGIDAKIQER-DLYIENIESELSKYKS--------RICRLEESIAVMEDRRYSL 795
            ++ + +  +    +E+    I +++ +  K K         ++   E+    ++     +
Sbjct: 1921 NRKEEKQTLQKYFEEQFAAIISHLKEDNEKLKQLHENHSVVQLNEKEQDFIQLKTNYALI 1980

Query: 796  ERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKN 855
            E++AD L S +Q +    ++   Q    ++ L VL   +  ++    E ++  +E+QK  
Sbjct: 1981 EQQADILKSLMQNE---IAQKKNQSQLNLSNLTVLQLFETFIQLNASEKQNLEEEIQKLK 2037

Query: 856  QILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQL-RDLES-NLK----- 908
                E++    +   D  ++ + +  + +     +S    YQT+L   LE  N K     
Sbjct: 2038 ISHTEKDSKYLLLTEDFAKYKDQIATEISNLK-EKSHKNDYQTELINQLEQKNAKVKQKC 2096

Query: 909  -RITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLE-AQLQE 966
             ++  + Q    Q K +I +LE +  TQIES   + K+L  + EK  + + Q+E ++ QE
Sbjct: 2097 SQLQEKLQETENQLKSQIFELEKQHQTQIESL--NSKILQIEQEKT-DAIKQIEQSKNQE 2153

Query: 967  YKNNIENLNM---NVEELNKMNLELID--KHVQKQQTQSPDYTEQYINEINKLNALLKQK 1021
              +N+   N    N+EE  K  L   +  ++ QK+Q +     E Y+N+ +  +  L+ +
Sbjct: 2154 IASNLLMTNQKISNLEEQFKQKLADFENIQNSQKKQKKKIQKEESYLNQESGND--LEDQ 2211

Query: 1022 DEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEEL 1081
            + +I  L          +    ++ + ++ +   + +N+EE+++   ++ +   Q   E 
Sbjct: 2212 ERQIKQLEDAYQKLMEQHERNQTEQQQEMKR---QYDNIEEQIRENLQKQMQLMQEKYER 2268

Query: 1082 QILVREQDDQIKE----LKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXX 1137
             +++ E  +QIKE     +E + + E+ I     +  S     +      VD        
Sbjct: 2269 SMVIYE--NQIKEEQSKYRELRQSHEIAIKNLNDLHFSQQKTVLDQSNEKVDLLKQQLSK 2326

Query: 1138 XXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQIN 1197
                 +   EE+  Q   + Q +  K    ++  Y   +Q+++L  +L+ H +   +   
Sbjct: 2327 YEELFQKSVEEQKQQFERISQSEIQKGIINVESEYK--LQIQSLQDKLS-HAMEKMQDCE 2383

Query: 1198 QLKSKLEQ----LNTENDNLLSTVAE--LRSSISSAVDQRGFEIAELWKQHLAQRE-ADF 1250
            QL  K E+    L  E D  +  V +  +     S ++Q    + EL +   AQ+E  + 
Sbjct: 2384 QLLKKKEEQEKNLIEEYDKKIVQVLQNDIACLQESLINQSKQNMKELSQIQNAQKEIGEI 2443

Query: 1251 QKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQ 1310
            Q+T  + ++Q +  +   +Q   ++Q+S Q   ++ +   Q   LQ K  +  + + +L 
Sbjct: 2444 QETIKQQKIQENNLKDLIQQHFSNIQTSLQAVKDESIK-NQSHQLQEKCNEIHQKILSLL 2502

Query: 1311 EKYADVINQIEILRSEIED-EKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILN 1369
            E    + N+  +   E E+ +K+A                 + +    ++K    +S+  
Sbjct: 2503 ESKHLLENKHAVASEEAEENQKLAKESKEMIISLNQKISEKEAQISQLNFKC---ESLNC 2559

Query: 1370 INEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQ 1429
              E+  +LKK                N  + ++ +LT Q   K+ +  +   E  I L Q
Sbjct: 2560 QIEQIKELKKLVESQKDDVIADLK--NRLQEQLTDLTSQN--KNDKALKNEEEKNIALQQ 2615

Query: 1430 RNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIE 1489
                 E+++ Q+  Y+ ++ +L  + + EL +L  K  +  N  +  ++E++ +  + IE
Sbjct: 2616 N---IEDLKSQVDNYKIKVSELETQIKYELQMLNEKKQDLENANKRFREENK-QLKEQIE 2671

Query: 1490 ELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRA 1549
            +LN    E+   N  V +L   L +++ + + ++  + NQ+ +  T   E+ N  N ++ 
Sbjct: 2672 KLNSNYQENKVANDSVTKLQTELNQKINEIDHLKEQIINQDKQFKTEKMELENRFNQMKE 2731

Query: 1550 SSSK 1553
            + +K
Sbjct: 2732 TLTK 2735



 Score =  118 bits (283), Expect = 2e-24
 Identities = 215/1166 (18%), Positives = 475/1166 (40%), Gaps = 99/1166 (8%)

Query: 476  NEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLN-DEIDAANKNMIKVKSNHK 534
            N   K +E+ + E N    ++N+K   ++  S   Q+TQ N  E D  + N  K  SN K
Sbjct: 1310 NTFVKEEEENQAE-NGNQHNLNIKCFDDEFSSNNNQMTQNNYTENDENSSNCKKFSSNQK 1368

Query: 535  LKLKQMQKTIDNFSK----VSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDS 590
                 M +     S     +S+ + EIV + +   +    +   + E    + +      
Sbjct: 1369 EIESDMDQPQAGSSGGKNGISNEDHEIVMMMQNCPYHQNLINNNQFENHVCKENTEQISQ 1428

Query: 591  GRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKY-----DEVEDKLA 645
               + +   ++ I++  L     K++ L+       + E   LQQ       +  ++ + 
Sbjct: 1429 YTDLVAASQQQQIQINTLMVQLQKSLKLICDLNDRNIIEKKKLQQSISSDVQNNTDNNID 1488

Query: 646  DISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVI---ENLKL------DKEQLYGTI 696
            D       QV   I  + +EE +    A   ++  ++   EN+KL      +K++L  ++
Sbjct: 1489 DDESTFYIQVRENIIEMKVEEALKKKYAEFDQIRDIVQCQENIKLAQNELSEKQKLLDSL 1548

Query: 697  KD-LENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDA 755
             D L+ D+E +M + Q   +E +   +K  K++ E     + K   E + K       D 
Sbjct: 1549 SDQLKIDQELLMKERQKLQEETVQFEEKQNKLTEE-----ILKQQQEYKEK------YDK 1597

Query: 756  KIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSE 815
             +Q+   Y +N+  +LS  K     L+  +++        + + ++    L E+Q+   +
Sbjct: 1598 YLQDFQEY-QNLMKQLSIQKVAQEELQNQLSLRSSLIKEQQEQLEKHLLNLTEQQQQLKD 1656

Query: 816  YTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQH 875
              +Q D+       L+++    + Q  + E E K++++K + + + +Q++ +    +++ 
Sbjct: 1657 IIVQFDKKKEDKNQLIEY---FQAQCEKQEEEIKQIKQKYEEIQKLSQDINLEKEIVKRE 1713

Query: 876  YNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQ 935
            +       N+ D+  S+   YQ ++ +  ++               KKE+E L +    +
Sbjct: 1714 HAQCQNSQNQIDIVRSD---YQNKISETNNS--------------NKKELEALNLALQEK 1756

Query: 936  IESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQK 995
             E     K+++    +     +  LE++++      +N +   ++L + N ELI   +++
Sbjct: 1757 NERIAEQKEMIKSLNQT----IKSLESKIENLSIKSDNYDETKQKLEQKNEELI--LLKQ 1810

Query: 996  QQTQSPDYTEQYINEINKLNALLKQKDEEII----ALNQKINNAQVSYMSMVSDYESKLA 1051
            Q  Q     + ++N++N L ++ ++             QKIN  Q+ +    ++ +++ A
Sbjct: 1811 QVAQEQKEKQIFLNQLNDLKSIDEKNQNNFTKKEEQYQQKINELQLQFQ---NEIKTESA 1867

Query: 1052 QFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEG 1111
            Q     +  + ++  + ++  +S Q  +E + + + +++QIK+L +  L  E N  K E 
Sbjct: 1868 QINKLRDEYQTKIDEMKEKYFESSQKMKEAEQISQFKEEQIKQL-QISLESEQNNRKEEK 1926

Query: 1112 MIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQEC 1171
              +    E                      LK   E   + + +  ++   +L T     
Sbjct: 1927 QTLQKYFE------EQFAAIISHLKEDNEKLKQLHENHSVVQLNEKEQDFIQLKTN---- 1976

Query: 1172 YTKIIQLETLNTELTGHDVVNQEQINQLK-SKLEQLNTENDNLLSTVAELRSSISSAVDQ 1230
            Y  I Q   +   L  +++  ++  +QL  S L  L    +  +   A  + ++   + +
Sbjct: 1977 YALIEQQADILKSLMQNEIAQKKNQSQLNLSNLTVLQL-FETFIQLNASEKQNLEEEIQK 2035

Query: 1231 RGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTME 1290
                  E   ++L   E DF K + ++  ++S  + K  +     +   Q E       +
Sbjct: 2036 LKISHTEKDSKYLLLTE-DFAKYKDQIATEISNLKEKSHKNDYQTELINQLEQKNAKVKQ 2094

Query: 1291 QVTSLQNKLQDKEEHLRN-LQEKYADVINQIEILRSEI-EDEKVAFXXXXXXXXXXXXXX 1348
            + + LQ KLQ+ E  L++ + E       QIE L S+I + E+                 
Sbjct: 2095 KCSQLQEKLQETENQLKSQIFELEKQHQTQIESLNSKILQIEQEKTDAIKQIEQSKNQEI 2154

Query: 1349 XXDLRTENQSYKQMQEQSILNI----NEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLE 1404
              +L   NQ    ++EQ    +    N +N+Q K+                ND E +  +
Sbjct: 2155 ASNLLMTNQKISNLEEQFKQKLADFENIQNSQKKQKKKIQKEESYLNQESGNDLEDQERQ 2214

Query: 1405 LTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEK-ESELAILR 1463
            +    +     + Q     T    +   +++N+ +Q+ E  ++   L  EK E  + I  
Sbjct: 2215 IKQLEDAYQKLMEQHERNQTEQQQEMKRQYDNIEEQIRENLQKQMQLMQEKYERSMVIYE 2274

Query: 1464 LKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEM- 1522
             ++ E  + Y  +++  EI  +K + +L+   ++  ++  Q  E    L+++++K  E+ 
Sbjct: 2275 NQIKEEQSKYRELRQSHEI-AIKNLNDLH--FSQQKTVLDQSNEKVDLLKQQLSKYEELF 2331

Query: 1523 QTALENQEIEIVTLNDE-----ITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMN 1577
            Q ++E Q+ +   ++       I N+++  +     +Q  +S A +  Q  ++ L     
Sbjct: 2332 QKSVEEQKQQFERISQSEIQKGIINVESEYKLQIQSLQDKLSHAMEKMQDCEQLL---KK 2388

Query: 1578 KELLDAVPRAELDLAMYMLHQRDVRC 1603
            KE  +     E D  +  + Q D+ C
Sbjct: 2389 KEEQEKNLIEEYDKKIVQVLQNDIAC 2414



 Score = 51.2 bits (117), Expect = 2e-04
 Identities = 85/436 (19%), Positives = 182/436 (41%), Gaps = 49/436 (11%)

Query: 509 EEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHH-L 567
           +  I Q    I    K +   +S  + KL+ +Q  +   +   D  K  V    ++H+  
Sbjct: 377 QNNIQQSQTNIQNYAKQLKIDRSKEEQKLRDLQNELSKINTAQDQYKSEVN---DIHYKC 433

Query: 568 SQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLV 627
           ++++ E E +   L L  ++Y   R  +  ++ K   ++ L +   +    L  Q+F   
Sbjct: 434 NERINEFERDFEKLHLAFINYK--RECDQTMFDKDQLIQQLRQELSQKNDKLLQQQFQYR 491

Query: 628 QELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKL 687
           Q  +  Q + +  +  + D +   ++ +   +  V        ++A+      +I N ++
Sbjct: 492 QSFYYNQYQMNLQDMAVGDNTNTNNNSISQLVSGV-------IINANNPNNPNLIHNNQI 544

Query: 688 DKEQLYGTIKDLE---NDKED----------IMNKLQNYIQENMDLTDKLEKMSAEKISE 734
                 G I  +    NDK+           I+NK  N   E     +  E M A     
Sbjct: 545 SSSNDGGDISPIAIIPNDKQPNSIFNSKEPIIINKRLNLDTEGGGDEEDQEIMQAFAEQG 604

Query: 735 LLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESI-AVMEDRRY 793
           LL  +N   Q K Q        +Q R  Y++ I  EL +Y+ +IC +E+    +M D + 
Sbjct: 605 LLKNLNW--QGKGQLVGAQQKALQIRQNYLKQILGEL-EYQ-QICEMEKIFDEIMRDNKS 660

Query: 794 SLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQK 853
                       +Q+ +  YS      +EL+ +L    D   V+++QL E++    +L++
Sbjct: 661 ------------VQDLRMKYSNIL---EELIKKLHQFKDKHEVLQQQLNELQQNCVKLRE 705

Query: 854 KNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHE 913
           +NQ +  E +     L+++++    ++ + ++T L      +Y+ +       L+   H+
Sbjct: 706 ENQKISNEYKKQMQKLNELKERLEKVITERDQTCLL---LNRYEKKEIITIKELQMEYHK 762

Query: 914 HQTLIVQKKKEIEDLE 929
            +  ++Q ++E++ L+
Sbjct: 763 KEEDLIQCQEEVDSLK 778



 Score = 45.2 bits (102), Expect = 0.015
 Identities = 84/412 (20%), Positives = 173/412 (41%), Gaps = 39/412 (9%)

Query: 145  THLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXX 204
            + + N  KE  N  +   +++K +E  ++  Q++++EK QI+    +             
Sbjct: 3544 SEIQNKEKELANFQNSNSIQIKNLEEQLIQSQKELDEKKQILSQLEERQKESELSIKQLQ 3603

Query: 205  XXXXXXXED-----TKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKL 259
                   E+     T Q  TK ++  I +    + EKQ  L D +S+    + L EA+  
Sbjct: 3604 EKLSQKQEEVVHLQTTQNATKEEKISILLSQIQELEKQ--LSDSKSEMKNKNQLSEAS-- 3659

Query: 260  LEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIA 319
            L  A+ +I++        LEQ                KQ++E S +EK E+ +    E++
Sbjct: 3660 LNEAKEKITI--------LEQKYSNLQKNYSLLESELKQALEKSKKEKDELIQTHQQELS 3711

Query: 320  NMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTA 379
             + +     E +  LN QI +   ++  K + +   S       K+   L  ++  + + 
Sbjct: 3712 QVQK-----EFIT-LNSQIEKNKIDMIEKDSQIKRISIEHDETQKQLESL--KQKYQQSL 3763

Query: 380  SKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXX 439
             +++   S+++        DK    ++I +L+   Q+   D ++KEY    ++       
Sbjct: 3764 EQLQLKESEITQLKKQMQLDKYEALSQIEQLKRE-QNNQIDQINKEY----QEKIQKLQS 3818

Query: 440  XXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVK 499
                G D   AQ   + +Q +E    I  G++ E  N I K++EQ ++ +     + ++ 
Sbjct: 3819 ELQKGNDE--AQ---KLRQQIESLQAISQGSSNEMQNLIQKMKEQQEENVK---SNQSIA 3870

Query: 500  DLIEKLKSAEEQITQLNDEIDAANKNMIKVKS-NHKLKLKQMQKTIDNFSKV 550
            +L  +L  +  Q  +LN +I      +   ++    LK ++ Q +  NF ++
Sbjct: 3871 ELQSQLVKSNLQANELNQKISKLESKLQSTENFIDALKKQENQSSKSNFGRI 3922



 Score = 42.7 bits (96), Expect = 0.080
 Identities = 98/491 (19%), Positives = 200/491 (40%), Gaps = 33/491 (6%)

Query: 560  LTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLL 619
            L ++LH    K   L+++   LQ + V         S+ YKK ++  N  + RL+ +   
Sbjct: 675  LIKKLHQFKDKHEVLQQQLNELQQNCVKLREENQKISNEYKKQMQKLNELKERLEKVITE 734

Query: 620  ESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELA 679
              Q         +L  +Y++ E  +  I +LQ +    E   +  +E++D+L     +L 
Sbjct: 735  RDQTC-------LLLNRYEKKE--IITIKELQMEYHKKEEDLIQCQEEVDSLKNQIDQLL 785

Query: 680  LVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKI 739
             ++     +KE       +       ++NK  ++I          E    + IS LL++I
Sbjct: 786  GIVGMFDSEKELAKQMHNESIQQFSIVLNKYDDFIIRLFQDYCHFEDNITQNISSLLSEI 845

Query: 740  NHEEQSK-IQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERK 798
                 SK I  ++     I+     I N      +  +    L      M +  Y++   
Sbjct: 846  IINVHSKDILDRY---ESIKRSIAQIYNKGRNNIQNVNNPSSLPPLNTQMPN-SYNIPGN 901

Query: 799  ADQLGSY--LQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIE-HENKELQKKN 855
             D + SY  L    +  ++    +  +  + + L +   +V  Q +    +++ + Q   
Sbjct: 902  RDSIRSYSPLLITNQLLNQNIPPQQNINMQSSFLQNTSGLVNGQFITNNVNKSSDYQYSC 961

Query: 856  QILLEENQNLQI---SLSDMQQHYN-ALVEKANRTDLAESESTKYQTQLRDLESNLKRIT 911
              L +   + QI      D+ +  N  + ++  R    E E +  + QL +LE    ++ 
Sbjct: 962  SSLDKNPTHPQIEDEEEEDVNEVNNLEISQRRQRRRDLEDEISNLKGQLAELEKKNNQLV 1021

Query: 912  HEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQ-EYKNN 970
             E      Q K+  + +E+ F +++E  I     L EK ++ I+ V Q+  ++  + K+ 
Sbjct: 1022 TERMHDYDQMKEHEQRVEL-FKSKLEQKITQ---LKEKEKQFIQMVRQITPEIDLKDKDE 1077

Query: 971  IENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEII-ALN 1029
            I+   +  + + K+  +LI   +Q+QQ+      +Q  N+ N+   L     ++ +  LN
Sbjct: 1078 IDYFEIKNQIVKKIQQDLI---MQQQQSSLSSILQQ--NQDNQSETLSGAGVQKYLQELN 1132

Query: 1030 QKINN-AQVSY 1039
              I    Q+SY
Sbjct: 1133 NSIQQIKQISY 1143



 Score = 41.9 bits (94), Expect = 0.14
 Identities = 89/444 (20%), Positives = 183/444 (41%), Gaps = 72/444 (16%)

Query: 918  IVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMN 977
            I++  K ++DL ++++  +E  I+      +K+E        L+ QL E + N   L   
Sbjct: 654  IMRDNKSVQDLRMKYSNILEELIKKLHQFKDKHE-------VLQQQLNELQQNCVKLR-- 704

Query: 978  VEELNKMNLELIDKHVQKQQTQSPDYTEQYINEI-NKLNALLKQKDEEIIALNQKINNAQ 1036
             EE  K++ E   K +QK            +NE+  +L  ++ ++D+  + LN+      
Sbjct: 705  -EENQKISNE-YKKQMQK------------LNELKERLEKVITERDQTCLLLNRYEKKEI 750

Query: 1037 VSYMSMVSDYESK---LAQFTTKLENMEEEMQRV--------SKQLLDSKQHNEELQ--- 1082
            ++   +  +Y  K   L Q   ++++++ ++ ++        S++ L  + HNE +Q   
Sbjct: 751  ITIKELQMEYHKKEEDLIQCQEEVDSLKNQIDQLLGIVGMFDSEKELAKQMHNESIQQFS 810

Query: 1083 ILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXL 1142
            I++ + DD I  L +    FE NI +     ISS +  +  + ++ D             
Sbjct: 811  IVLNKYDDFIIRLFQDYCHFEDNITQN----ISSLLSEIIINVHSKDILDRYESIKRSIA 866

Query: 1143 KVQEEEEFIQERSVLQEQSAKLNTELQECYT--------KIIQLETLNTELTGHDVVNQE 1194
            ++  +     +          LNT++   Y         +      +  +L   ++  Q+
Sbjct: 867  QIYNKGRNNIQNVNNPSSLPPLNTQMPNSYNIPGNRDSIRSYSPLLITNQLLNQNIPPQQ 926

Query: 1195 QINQLKSKLE--------QLNTENDNLLSTVAELRSSIS------SAVDQRGFEIAELWK 1240
             IN   S L+        Q  T N N  S      SS+          D+   ++ E+  
Sbjct: 927  NINMQSSFLQNTSGLVNGQFITNNVNKSSDYQYSCSSLDKNPTHPQIEDEEEEDVNEVNN 986

Query: 1241 QHLAQREADFQKTEHE---LRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQ-VTSLQ 1296
              ++QR    +  E E   L+ QL+  E K  QL+    +    + +++   EQ V   +
Sbjct: 987  LEISQRRQRRRDLEDEISNLKGQLAELEKKNNQLV----TERMHDYDQMKEHEQRVELFK 1042

Query: 1297 NKLQDKEEHLRNLQEKYADVINQI 1320
            +KL+ K   L+  ++++  ++ QI
Sbjct: 1043 SKLEQKITQLKEKEKQFIQMVRQI 1066



 Score = 38.7 bits (86), Expect = 1.3
 Identities = 30/111 (27%), Positives = 60/111 (54%), Gaps = 6/111 (5%)

Query: 1433 EFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKE-SEIER--VKLIE 1489
            E E +  +++   K ++DL  +  + L  L  K+H+  + +E +Q++ +E+++  VKL E
Sbjct: 646  EMEKIFDEIMRDNKSVQDLRMKYSNILEELIKKLHQFKDKHEVLQQQLNELQQNCVKLRE 705

Query: 1490 ELNVKITESVSLNKQ-VAELNKALEEEVAKTNEMQTALENQE-IEIVTLND 1538
            E N KI+       Q + EL + LE+ + + ++    L   E  EI+T+ +
Sbjct: 706  E-NQKISNEYKKQMQKLNELKERLEKVITERDQTCLLLNRYEKKEIITIKE 755


>UniRef50_A2EZ87 Cluster: Viral A-type inclusion protein, putative;
            n=2; cellular organisms|Rep: Viral A-type inclusion
            protein, putative - Trichomonas vaginalis G3
          Length = 2271

 Score =  187 bits (455), Expect = 3e-45
 Identities = 273/1313 (20%), Positives = 572/1313 (43%), Gaps = 127/1313 (9%)

Query: 296  AKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTE 355
            A+ +IE   EE   + ++  L    +  +T+K + ++  +  +    K   NK   M   
Sbjct: 112  AQSAIEKLREENETMRKENKLLATKLQAITEKYKSIKEKDRTLLDNYKVASNKFREM--R 169

Query: 356  SKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQ 415
            +K  S+  + G  + S+     T  K+     Q     LNQ  + +   NE+      + 
Sbjct: 170  NKYESNIRQYGQVVDSK---METDQKLVDLMQQ-QQNLLNQKNELEAKLNEVTTNNESLA 225

Query: 416  SLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDV 475
            + NK L +K+Y   +               +   A+            +   +  N + +
Sbjct: 226  AKNKSL-EKQYRDLQNQVEDLNNQNIDLQNEAESAKNSAVKVTRALKKAERKLAKNEQQI 284

Query: 476  NEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKL 535
             E  ++ ++  QE ++E  +  +++  + L+SA+E++ +L  E      N +K K+N+KL
Sbjct: 285  EEHERIHKE-HQEAHEE-SNKQLQECTKLLQSAQEKLKELQLE-----NNDLK-KANNKL 336

Query: 536  KLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIE 595
                   T DN +K+ ++  +  +    +  ++Q +  +E EK  LQ  L  Y      +
Sbjct: 337  -------TRDN-TKLQNNVAKHEKSVSMMESMNQSIQNIESEKSELQNQLQQY------Q 382

Query: 596  SDVYKKMIEMENL---AETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQS 652
             ++ K++ E+E L    ET     + L+++   L + L  LQ   D +     +   L+ 
Sbjct: 383  QEIAKRLKEIEGLQKQTETLFNKNNTLQNENSALTENLSQLQ---DNLSKSKKEAKSLRK 439

Query: 653  DQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQN 712
              + +  ++++ ++ I AL  S  +    I++L+ D E     I+  E+  +++ ++ Q 
Sbjct: 440  QGITAAKEALNFQQNIVALQKSLLDAHHEIDDLRRDVEDKNSKIQANESRVKELEDQNQL 499

Query: 713  YIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELS 772
               EN DL ++ ++  + K  E+  K ++E + K+QT   ID   Q+ D     ++ + +
Sbjct: 500  LEDENKDLEEEAQQYISNKEEEMNKKKSNEVK-KLQTL--IDQLKQQND----QLQQQNN 552

Query: 773  KYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMD 832
            +    I + EE +A +ED +  + ++  Q     Q K K  +  +   DEL N++  L  
Sbjct: 553  ELHDEIEQKEEDLAKLEDEKQQIFQQNQQ----RQLKIKELTNKSQNNDELQNQIKQLKS 608

Query: 833  HDRVVEKQLLEIEHE----NKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDL 888
                 + QL ++ +E    +KE++++N+ L  + +     +S +Q     + E A +  +
Sbjct: 609  ELENTQNQLQKVTNEKGDKSKEIEEQNKKLKSQIEERDQMISKLQDENQKIAETAEQAAI 668

Query: 889  AESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNE 948
              SE+ K       L    K++  E+ +L  + +K+++DL  + + + E  ++ KK  +E
Sbjct: 669  KSSETNK------KLREQFKKVYAENTSLKAKNEKQVQDLMQQLDEK-EKQLQSKK--DE 719

Query: 949  KYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYI 1008
             Y++  + + +    L +    IEN  + +EE +  N+    + ++++  +  +  +   
Sbjct: 720  NYKQENDQLKKENQDLMDKLKEIENERVELEE-DVKNVTTEKEDLEEEIEKLKEKVDVLE 778

Query: 1009 NEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVS 1068
            +++  L    K++ E      Q+IN +    M M+ D   K+    T+L+N        +
Sbjct: 779  DQLETLTDEHKKQQEN---HEQQINKSNDENM-MLRDQMKKIFAENTQLKNTN------T 828

Query: 1069 KQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNV 1128
             Q L+  Q N +LQ  + E+D QIK+ ++     E++  KT+ ++ S   +  ++D   V
Sbjct: 829  NQELELAQKNHDLQRKLDEKDQQIKQKQD-----EIDELKTK-VLASEEFQKTTNDLQRV 882

Query: 1129 DXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQL-ETLNTELTG 1187
                         LK   E      +++  +   K N E+Q    +I+ L E +   +  
Sbjct: 883  AEELKEKTKQIDDLKNINE----NLQNIKNDDLKKANEEIQNKQKQIVDLQEKIKETIKE 938

Query: 1188 HDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAEL--WKQHLAQ 1245
            ++ +NQ+ + +L+ +LE L  E+     T  +    I+ AVD+    I ++   K     
Sbjct: 939  NEELNQKNL-ELEEELEALTEEHKKQQETHEQ---QINKAVDENTKLIDQMKKLKNTNTN 994

Query: 1246 READFQKTEHELRVQLSAFESKYEQLLDSVQS--------STQEETNKIVTMEQVTSLQN 1297
            +E +  +  H+L+ Q++  +   E LL+ +QS          Q++ N +    +    Q 
Sbjct: 995  QELELAQKNHDLQKQVNDLKKSNEDLLNQIQSDDSKKTIEDLQKQVNDLKISNEYLLKQI 1054

Query: 1298 KLQDKEEHLRNLQEKYADVINQIE----ILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLR 1353
            +  D +  +  L++   D+  + +    IL+  +++                       R
Sbjct: 1055 QNNDSQAQIEELKKSNDDLQKKYDENEKILKDLLQENNALEEQFKEISRMNDHLKGETER 1114

Query: 1354 TE--NQSYK---QMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQ 1408
             E  N  YK   Q +++ I  ++ EN  L K +             + D + K+ +L   
Sbjct: 1115 QENINNRYKQSSQKKDEVISELHNENDDLSKEN-------DDLTKEIEDLKTKISKLNED 1167

Query: 1409 LELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHE 1468
             + +  ++  +  +    LTQ+ND +EN+ ++  + +K  EDLT E E  +A       E
Sbjct: 1168 HKKEIKQLLDQIEQKNDLLTQQND-YENLMKENDDLDKENEDLTKENEQLVAEKETLCQE 1226

Query: 1469 NANHYETMQKESEIERVKLIEELNVKITESV-SLNKQVAELNKALEEEVAKTNEMQTALE 1527
            N    E ++K   ++  K+ +E+  ++ + + +L K+   L K  E+  +  N ++ A  
Sbjct: 1227 N----ERLKK--ALDDSKIFDEIQKELQDKIDNLEKENDNLKKENEKIQSLKNALELAKS 1280

Query: 1528 NQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQL--DNTMNK 1578
              + E  ++ DEI  L+         IQK + F     +  +E L  +N M K
Sbjct: 1281 TFDKE-KSIEDEIRKLEK----EHKDIQKQI-FGDKQNEEEEEDLSDENEMTK 1327



 Score =  170 bits (413), Expect = 3e-40
 Identities = 264/1351 (19%), Positives = 586/1351 (43%), Gaps = 105/1351 (7%)

Query: 306  EKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKK 365
            +K E+E K +    N   L  K + LE     ++   ++L N+   +  E+++  + + K
Sbjct: 206  QKNELEAKLNEVTTNNESLAAKNKSLEKQYRDLQNQVEDLNNQNIDLQNEAESAKNSAVK 265

Query: 366  GSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKE 425
             +  + +K+ R  A   +           +Q+  ++ NK ++ +   ++QS  + L  KE
Sbjct: 266  VTRAL-KKAERKLAKNEQQIEEHERIHKEHQEAHEESNK-QLQECTKLLQSAQEKL--KE 321

Query: 426  YVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIH-VGTNTEDV-NEIAKVQE 483
              +   D            +D    +LQ    +H +  S++  +  + +++ +E +++Q 
Sbjct: 322  LQLENNDLKKANNKLT---RDN--TKLQNNVAKHEKSVSMMESMNQSIQNIESEKSELQN 376

Query: 484  QLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKT 543
            QL+Q   +  K   +K+ IE L+   E +   N+ +   N  + +  S  +  L + +K 
Sbjct: 377  QLQQYQQEIAK--RLKE-IEGLQKQTETLFNKNNTLQNENSALTENLSQLQDNLSKSKKE 433

Query: 544  IDNFSKVS-DSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKM 602
              +  K    + KE +   + +  L + + +   E  +L+  + D +S         K++
Sbjct: 434  AKSLRKQGITAAKEALNFQQNIVALQKSLLDAHHEIDDLRRDVEDKNSKIQANESRVKEL 493

Query: 603  IEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQL--QSDQVCSEIK 660
             +   L E   K +   E+Q++   +E  + ++K +EV+     I QL  Q+DQ+  +  
Sbjct: 494  EDQNQLLEDENKDLEE-EAQQYISNKEEEMNKKKSNEVKKLQTLIDQLKQQNDQLQQQNN 552

Query: 661  SVH-----LEEQIDALSASKKEL-------ALVIENL---KLDKEQLYGTIKDLENDKED 705
             +H      EE +  L   K+++        L I+ L     + ++L   IK L+++ E+
Sbjct: 553  ELHDEIEQKEEDLAKLEDEKQQIFQQNQQRQLKIKELTNKSQNNDELQNQIKQLKSELEN 612

Query: 706  IMNKLQNYIQENMDLTDKLE------KMSAEKISELLAKINHEEQSKIQT--QFGIDAKI 757
              N+LQ    E  D + ++E      K   E+  ++++K+  E Q   +T  Q  I +  
Sbjct: 613  TQNQLQKVTNEKGDKSKEIEEQNKKLKSQIEERDQMISKLQDENQKIAETAEQAAIKSSE 672

Query: 758  QERDL--YIENIESELSKYKSRICR-LEESIAVMEDRRYSLERKADQLGSYLQEKQKAYS 814
              + L    + + +E +  K++  + +++ +  ++++   L+ K D+  +Y QE  +   
Sbjct: 673  TNKKLREQFKKVYAENTSLKAKNEKQVQDLMQQLDEKEKQLQSKKDE--NYKQENDQLKK 730

Query: 815  EYTIQED---ELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSD 871
            E     D   E+ N    L +  + V  +  ++E E ++L++K  +L ++ + L      
Sbjct: 731  ENQDLMDKLKEIENERVELEEDVKNVTTEKEDLEEEIEKLKEKVDVLEDQLETLTDEHKK 790

Query: 872  MQQHYNALVEKANRTDLAESESTKY----QTQLRDLESNLKRITHEHQTLIVQKKKEIED 927
             Q+++   + K+N  ++   +  K      TQL++  +N + +    +   +Q+K + +D
Sbjct: 791  QQENHEQQINKSNDENMMLRDQMKKIFAENTQLKNTNTN-QELELAQKNHDLQRKLDEKD 849

Query: 928  LEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIE---NLNMNVEELNKM 984
             +I+        ++ K + +E+++K    + ++  +L+E    I+   N+N N++ +   
Sbjct: 850  QQIKQKQDEIDELKTKVLASEEFQKTTNDLQRVAEELKEKTKQIDDLKNINENLQNIKND 909

Query: 985  NLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQK----DEEIIALNQKINNAQVSYM 1040
            +L+  ++ +Q +Q Q  D  E+ I E  K N  L QK    +EE+ AL ++    Q ++ 
Sbjct: 910  DLKKANEEIQNKQKQIVDLQEK-IKETIKENEELNQKNLELEEELEALTEEHKKQQETHE 968

Query: 1041 SMVS---DYESKLAQFTTKLEN--------MEEEMQRVSKQLLDSKQHNEELQILVREQD 1089
              ++   D  +KL     KL+N        + ++   + KQ+ D K+ NE+L   + + D
Sbjct: 969  QQINKAVDENTKLIDQMKKLKNTNTNQELELAQKNHDLQKQVNDLKKSNEDLLNQI-QSD 1027

Query: 1090 DQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEE-- 1147
            D  K +++  L  ++N  K     +   I+  +D    ++                E+  
Sbjct: 1028 DSKKTIED--LQKQVNDLKISNEYLLKQIQN-NDSQAQIEELKKSNDDLQKKYDENEKIL 1084

Query: 1148 EEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLN 1207
            ++ +QE + L+EQ  +++        +  + E +N           E I++L ++ + L+
Sbjct: 1085 KDLLQENNALEEQFKEISRMNDHLKGETERQENINNRYKQSSQKKDEVISELHNENDDLS 1144

Query: 1208 TENDNLLSTVAELRSSISSAVDQRGFEIAEL-----WKQHLAQREADFQ---KTEHELRV 1259
             END+L   + +L++ IS   +    EI +L      K  L  ++ D++   K   +L  
Sbjct: 1145 KENDDLTKEIEDLKTKISKLNEDHKKEIKQLLDQIEQKNDLLTQQNDYENLMKENDDLDK 1204

Query: 1260 QLSAFESKYEQLLDSVQSSTQEETNKIVTMEQ---VTSLQNKLQDKEEHLRNLQEKYADV 1316
            +      + EQL+   ++  QE       ++       +Q +LQDK ++L    +     
Sbjct: 1205 ENEDLTKENEQLVAEKETLCQENERLKKALDDSKIFDEIQKELQDKIDNLEKENDNLKKE 1264

Query: 1317 INQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQ-EQSILNINEENA 1375
              +I+ L++ +E  K  F                    + Q +   Q E+   ++++EN 
Sbjct: 1265 NEKIQSLKNALELAKSTFDKEKSIEDEIRKLEKEHKDIQKQIFGDKQNEEEEEDLSDENE 1324

Query: 1376 QLK-KSSXXXXXXXXXXXXRVNDAEAKVLELTHQL-ELKDSEI-YQKTHEYTITLTQRND 1432
              K +              +VN+    +  L H+L + +D+ +   +       L Q  +
Sbjct: 1325 MTKIRREVEDLKKDALIQIKVNE----IQRLEHELSQAQDNSVPLVQFQSMADNLEQTVE 1380

Query: 1433 EFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELN 1492
            E + +++++   +  + +    + SEL I      +  +       + E E +KL ++L 
Sbjct: 1381 ENKQLKEKMKLIDNELTNKLEFENSELKIDLDNYSKQLDDANAKISKLEKENIKLKDKLE 1440

Query: 1493 VKITE--SVSLNKQVAELNKALEEEVAKTNEM----QTALENQEIEIVTLNDEITNLQNM 1546
             + +E   + +  +  ++  A+  ++ K  +     +T +   E E  TL  +++ L+N 
Sbjct: 1441 KEESEKSDMIIKYENLKMENAVSGDIDKIKDQLKDKETDIVGLEAERNTLMKKLSELENK 1500

Query: 1547 VRASSSKIQKHVSFASDTKQGRDEQLDNTMN 1577
            V+ +  KI K +       +   EQL+N  N
Sbjct: 1501 VQENDEKI-KEIEDLKKENEELKEQLENNNN 1530



 Score =  149 bits (361), Expect = 6e-34
 Identities = 295/1395 (21%), Positives = 600/1395 (43%), Gaps = 156/1395 (11%)

Query: 216  QQMTKMQENFIAMEAEWKD---EKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHS 272
            ++    Q+N +A++    D   E   L +D+E K+ +I + E   K LE     +  E+ 
Sbjct: 446  KEALNFQQNIVALQKSLLDAHHEIDDLRRDVEDKNSKIQANESRVKELEDQNQLLEDENK 505

Query: 273  KLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLE 332
             L +E +Q                         ++ E+ +K S E+  +  L   I+ L+
Sbjct: 506  DLEEEAQQYIS---------------------NKEEEMNKKKSNEVKKLQTL---IDQLK 541

Query: 333  HLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSE 392
              N Q++Q N EL +++     +   +    ++   +  +   R    K  +  SQ + E
Sbjct: 542  QQNDQLQQQNNELHDEIEQKEEDLAKLEDEKQQ---IFQQNQQRQLKIKELTNKSQNNDE 598

Query: 393  TLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQL 452
              NQ    K  K+E+   +  +Q +  +  DK   I E++            +D +I++L
Sbjct: 599  LQNQI---KQLKSELENTQNQLQKVTNEKGDKSKEIEEQNKKLKSQIEE---RDQMISKL 652

Query: 453  QLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQEL--NDEIKDVN---VKDLIEKLKS 507
            Q E+Q+  E          + + N+  K++EQ K+    N  +K  N   V+DL+++L  
Sbjct: 653  QDENQKIAETAE--QAAIKSSETNK--KLREQFKKVYAENTSLKAKNEKQVQDLMQQLDE 708

Query: 508  AEEQITQLNDEIDAANKNMIKVKSNHKL--KLKQMQ-KTIDNFSKVSDSNKEIVRLTEEL 564
             E+Q+    DE      + +K K N  L  KLK+++ + ++    V +   E   L EE+
Sbjct: 709  KEKQLQSKKDENYKQENDQLK-KENQDLMDKLKEIENERVELEEDVKNVTTEKEDLEEEI 767

Query: 565  HHLSQKVAELEEEKGNL-QLHLVDYDSG--RMIESDVYKKMI--EMENLAETRLKAISLL 619
              L +KV  LE++   L   H    ++   ++ +S+    M+  +M+ +     +  +  
Sbjct: 768  EKLKEKVDVLEDQLETLTDEHKKQQENHEQQINKSNDENMMLRDQMKKIFAENTQLKNTN 827

Query: 620  ESQKFDLVQELHILQQKYDE----VEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASK 675
             +Q+ +L Q+ H LQ+K DE    ++ K  +I +L++  + SE +       +  ++   
Sbjct: 828  TNQELELAQKNHDLQRKLDEKDQQIKQKQDEIDELKTKVLASE-EFQKTTNDLQRVAEEL 886

Query: 676  KELALVIENLKLDKEQLYGTIKD-LENDKEDIMNK------LQNYIQENMDLTDKLEKMS 728
            KE    I++LK   E L     D L+   E+I NK      LQ  I+E +   ++L + +
Sbjct: 887  KEKTKQIDDLKNINENLQNIKNDDLKKANEEIQNKQKQIVDLQEKIKETIKENEELNQKN 946

Query: 729  AEKISELLAKIN-HEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAV 787
             E   EL A    H++Q +   Q  I+  + E    I+ ++   +   ++   L +    
Sbjct: 947  LELEEELEALTEEHKKQQETHEQ-QINKAVDENTKLIDQMKKLKNTNTNQELELAQKNHD 1005

Query: 788  MEDRRYSLERKADQLGSYLQ--EKQKAYSEYTIQEDELV--NRLAVLMDHDRVVEKQLLE 843
            ++ +   L++  + L + +Q  + +K   +   Q ++L   N   +    +   + Q+ E
Sbjct: 1006 LQKQVNDLKKSNEDLLNQIQSDDSKKTIEDLQKQVNDLKISNEYLLKQIQNNDSQAQIEE 1065

Query: 844  IEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDL 903
            ++  N +LQKK     +EN+ +   L D+ Q  NAL E+                +  ++
Sbjct: 1066 LKKSNDDLQKK----YDENEKI---LKDLLQENNALEEQFKEISRMNDHLKGETERQENI 1118

Query: 904  ESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKV----LNEKYEKNI-EYVT 958
             +  K+ + +   +I +   E +DL  E N  +   I D K     LNE ++K I + + 
Sbjct: 1119 NNRYKQSSQKKDEVISELHNENDDLSKE-NDDLTKEIEDLKTKISKLNEDHKKEIKQLLD 1177

Query: 959  QLEAQ--LQEYKNNIENLNMNVEELNKMNLELIDKHVQ---KQQT--QSPDYTEQYINEI 1011
            Q+E +  L   +N+ ENL    ++L+K N +L  ++ Q   +++T  Q  +  ++ +++ 
Sbjct: 1178 QIEQKNDLLTQQNDYENLMKENDDLDKENEDLTKENEQLVAEKETLCQENERLKKALDDS 1237

Query: 1012 NKLNALLKQKDEEIIAL-----NQKINNAQV----SYMSMVSDYESKLAQFTTKLENMEE 1062
               + + K+  ++I  L     N K  N ++    + + +      K      ++  +E+
Sbjct: 1238 KIFDEIQKELQDKIDNLEKENDNLKKENEKIQSLKNALELAKSTFDKEKSIEDEIRKLEK 1297

Query: 1063 EMQRVSKQLLDSKQHNEELQILVREQD-DQIK-ELKETKLTFEMNIPKTEGMIISSTIEP 1120
            E + + KQ+   KQ+ EE + L  E +  +I+ E+++ K    + I   E   +   +  
Sbjct: 1298 EHKDIQKQIFGDKQNEEEEEDLSDENEMTKIRREVEDLKKDALIQIKVNEIQRLEHELSQ 1357

Query: 1121 MSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQ-EQSAKL---NTELQ---ECYT 1173
              D  N+V               V+E ++  ++  ++  E + KL   N+EL+   + Y+
Sbjct: 1358 AQD--NSVPLVQFQSMADNLEQTVEENKQLKEKMKLIDNELTNKLEFENSELKIDLDNYS 1415

Query: 1174 KIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGF 1233
            K  QL+  N +++    + +E I +LK KLE+  +E  +++     L+  + +AV     
Sbjct: 1416 K--QLDDANAKISK---LEKENI-KLKDKLEKEESEKSDMIIKYENLK--MENAVSG--- 1464

Query: 1234 EIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVT 1293
            +I ++ K  L  +E D    E E    +        ++ ++ +   + E  K    E   
Sbjct: 1465 DIDKI-KDQLKDKETDIVGLEAERNTLMKKLSELENKVQENDEKIKEIEDLKKENEELKE 1523

Query: 1294 SLQNKLQDKEEHLRN----LQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXX 1349
             L+N   D EE L+N    L+ +   + N++E+  SE++ +K                  
Sbjct: 1524 QLENNNNDVEERLQNDNNMLKREITKLKNKLEL--SEVDKKK------ADEGVKTMMEKY 1575

Query: 1350 XDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQL 1409
              +  EN   K   E+  L+ N+E    K++              V   ++   E     
Sbjct: 1576 NKISEENMLLKHHIEE--LSQNKEEKSDKENLNESKPLSSGLATPVKSKDSFFGE----- 1628

Query: 1410 ELKDSEIYQKTHEYTITLTQR-----NDEFENVRQQLVEYEKRIEDLTYEK---ESELAI 1461
            +     ++  T  ++ T + R      DEF++      E E+ I+++  EK      L  
Sbjct: 1629 DSSSDNLFNITQPHSSTSSPRRQYMVEDEFDS-NNSHKEEEEEIDEVKPEKGLINLSLDA 1687

Query: 1462 LRLKMHENANHYETMQKESEIERVKLIEEL--NVKITESVSLNKQ-VAELN-KALEEEVA 1517
            ++ K     +     +K  E E+ K  EE+   +++ +++   K  + E++ K L+E   
Sbjct: 1688 IKQKYERRRSSAAQPKKSDEEEQTKEEEEIVSGIEVIDNLEPPKSPLREISEKDLDENFP 1747

Query: 1518 KTNEMQTALENQEIE 1532
              +   + LEN++++
Sbjct: 1748 DVSSSNSPLENEDMK 1762



 Score =  128 bits (309), Expect = 1e-27
 Identities = 212/1011 (20%), Positives = 414/1011 (40%), Gaps = 103/1011 (10%)

Query: 665  EEQIDALSASKKELALVIENLKLDKEQLYGT---IKDLENDKEDIMNKLQNYI----QEN 717
            ++ I    A  +EL   + +L+   +Q Y T   + D + + + I   LQ  I    Q N
Sbjct: 26   QKTIQTYQAQVQELTDQVRDLESRLDQSYNTQTQMFDSDTENQSIQQTLQERIRQLSQRN 85

Query: 718  MDLTDKLEKMSAEKISELLAKI-NHEEQSKIQT-QFGIDAKIQERDLYIENIESELSKYK 775
             +L +      A   ++  A I N E QS I+  +   +   +E  L    +++   KYK
Sbjct: 86   SELKNSRINSPAVSSTKRSASIANPEAQSAIEKLREENETMRKENKLLATKLQAITEKYK 145

Query: 776  SRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDR 835
            S    ++E    + D       K  ++ +  +   + Y +    + E   +L  LM   +
Sbjct: 146  S----IKEKDRTLLDNYKVASNKFREMRNKYESNIRQYGQVVDSKMETDQKLVDLMQQQQ 201

Query: 836  VVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHY----NALVEKANRTDLAES 891
             +  Q  E+E +  E+   N+ L  +N++L+    D+Q       N  ++  N  + A++
Sbjct: 202  NLLNQKNELEAKLNEVTTNNESLAAKNKSLEKQYRDLQNQVEDLNNQNIDLQNEAESAKN 261

Query: 892  ESTKYQTQLRDLESNL----------KRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIR 941
             + K    L+  E  L          +RI  EHQ    +  K++++   +     +  ++
Sbjct: 262  SAVKVTRALKKAERKLAKNEQQIEEHERIHKEHQEAHEESNKQLQEC-TKLLQSAQEKLK 320

Query: 942  DKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMN--LELIDKHVQKQQTQ 999
            + ++ N   +K    +T+   +LQ   NN+     +V  +  MN  ++ I+    + Q Q
Sbjct: 321  ELQLENNDLKKANNKLTRDNTKLQ---NNVAKHEKSVSMMESMNQSIQNIESEKSELQNQ 377

Query: 1000 SPDYTEQYINEINKLNALLKQKDEEIIALN--QKINNAQVSYMSMVSDYESKLAQFTTKL 1057
               Y ++    + ++  L KQ +      N  Q  N+A    +S + D  SK  +    L
Sbjct: 378  LQQYQQEIAKRLKEIEGLQKQTETLFNKNNTLQNENSALTENLSQLQDNLSKSKKEAKSL 437

Query: 1058 E-----------NMEEEMQRVSKQLLDSKQHNEELQILVREQ-------DDQIKELKETK 1099
                        N ++ +  + K LLD+    ++L+  V ++       + ++KEL++  
Sbjct: 438  RKQGITAAKEALNFQQNIVALQKSLLDAHHEIDDLRRDVEDKNSKIQANESRVKELEDQN 497

Query: 1100 LTFE---MNIPKTEGMIISSTIEPM----SDDANNVDXXXXXXXXXXXXLKVQEEEEFIQ 1152
               E    ++ +     IS+  E M    S++   +             L+ Q+  E   
Sbjct: 498  QLLEDENKDLEEEAQQYISNKEEEMNKKKSNEVKKLQTLIDQLKQQNDQLQ-QQNNELHD 556

Query: 1153 ERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVN---QEQINQLKSKLE----- 1204
            E    +E  AKL  E Q+ + +  Q +    ELT     N   Q QI QLKS+LE     
Sbjct: 557  EIEQKEEDLAKLEDEKQQIFQQNQQRQLKIKELTNKSQNNDELQNQIKQLKSELENTQNQ 616

Query: 1205 --QLNTENDNLLSTVAELRSSISSAVDQRGFEIAELW--KQHLA----QREADFQKTEHE 1256
              ++  E  +    + E    + S +++R   I++L    Q +A    Q      +T  +
Sbjct: 617  LQKVTNEKGDKSKEIEEQNKKLKSQIEERDQMISKLQDENQKIAETAEQAAIKSSETNKK 676

Query: 1257 LRVQL-------SAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNL 1309
            LR Q        ++ ++K E+ +  +     E+  ++ + +     Q   Q K+E+ ++L
Sbjct: 677  LREQFKKVYAENTSLKAKNEKQVQDLMQQLDEKEKQLQSKKDENYKQENDQLKKEN-QDL 735

Query: 1310 QEKYADVINQIEILRSEIED---EKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQ--- 1363
             +K  ++ N+   L  ++++   EK                    L T    +K+ Q   
Sbjct: 736  MDKLKEIENERVELEEDVKNVTTEKEDLEEEIEKLKEKVDVLEDQLETLTDEHKKQQENH 795

Query: 1364 EQSILNINEENA----QLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQK 1419
            EQ I   N+EN     Q+KK              +  +   K  +L  +L+ KD +I QK
Sbjct: 796  EQQINKSNDENMMLRDQMKKIFAENTQLKNTNTNQELELAQKNHDLQRKLDEKDQQIKQK 855

Query: 1420 THEYTITLTQ--RNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQ 1477
              E     T+   ++EF+     L    + +++ T ++  +L  +   + +N  + +  +
Sbjct: 856  QDEIDELKTKVLASEEFQKTTNDLQRVAEELKEKT-KQIDDLKNINENL-QNIKNDDLKK 913

Query: 1478 KESEIE-RVKLIEELNVKITESVSLNKQVAELNKALEEEV-AKTNEMQTALENQEIEIVT 1535
               EI+ + K I +L  KI E++  N+++ + N  LEEE+ A T E +   E  E +I  
Sbjct: 914  ANEEIQNKQKQIVDLQEKIKETIKENEELNQKNLELEEELEALTEEHKKQQETHEQQINK 973

Query: 1536 LNDEITNL-QNMVRASSSKIQKHVSFASDTKQGRDEQLD-NTMNKELLDAV 1584
              DE T L   M +  ++   + +  A      + +  D    N++LL+ +
Sbjct: 974  AVDENTKLIDQMKKLKNTNTNQELELAQKNHDLQKQVNDLKKSNEDLLNQI 1024



 Score =  124 bits (300), Expect = 2e-26
 Identities = 209/1036 (20%), Positives = 449/1036 (43%), Gaps = 99/1036 (9%)

Query: 147  LSNTIKEKDNALSVLQVK-MKIMETT------ILDLQEKINEKDQIIEAKNKATTXXXXX 199
            L + I+E+D  +S LQ +  KI ET         +  +K+ E+ + + A+N  T+     
Sbjct: 638  LKSQIEERDQMISKLQDENQKIAETAEQAAIKSSETNKKLREQFKKVYAEN--TSLKAKN 695

Query: 200  XXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKL 259
                        E  KQ  +K  EN+     + K E Q L+  ++  +     LEE  K 
Sbjct: 696  EKQVQDLMQQLDEKEKQLQSKKDENYKQENDQLKKENQDLMDKLKEIENERVELEEDVKN 755

Query: 260  LEAARFEISLEHSKLAQE---LEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSL 316
            +   + ++  E  KL ++   LE                 +Q I  S +E   + ++   
Sbjct: 756  VTTEKEDLEEEIEKLKEKVDVLEDQLETLTDEHKKQQENHEQQINKSNDENMMLRDQMKK 815

Query: 317  EIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSP-SKKGSPLISRKSG 375
              A  T+L K     + L  ++ Q N +L+ KL     + K       +  + +++ +  
Sbjct: 816  IFAENTQL-KNTNTNQEL--ELAQKNHDLQRKLDEKDQQIKQKQDEIDELKTKVLASEEF 872

Query: 376  RNTASKMKSPWSQLSSETLNQDTDKKINKN-------EIAKLEMVIQSLNKDLVDKEYVI 428
            + T + ++    +L  +T   D  K IN+N       ++ K    IQ+  K +VD +  I
Sbjct: 873  QKTTNDLQRVAEELKEKTKQIDDLKNINENLQNIKNDDLKKANEEIQNKQKQIVDLQEKI 932

Query: 429  SEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQE 488
             E               +  +  L  EH++  E     H     + V+E  K+ +Q+K  
Sbjct: 933  KETIKENEELNQKNLELEEELEALTEEHKKQQE----THEQQINKAVDENTKLIDQMK-- 986

Query: 489  LNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMI-KVKSNHKLK-LKQMQKTIDN 546
               ++K+ N    +E  +   +   Q+ND +  +N++++ +++S+   K ++ +QK +++
Sbjct: 987  ---KLKNTNTNQELELAQKNHDLQKQVND-LKKSNEDLLNQIQSDDSKKTIEDLQKQVND 1042

Query: 547  FSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEME 606
              K+  SN+ +++  +     +Q + EL++   +LQ     YD    I     K +++  
Sbjct: 1043 L-KI--SNEYLLKQIQNNDSQAQ-IEELKKSNDDLQ---KKYDENEKI----LKDLLQEN 1091

Query: 607  NLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLAD-ISQLQSDQVCSEIKSVHLE 665
            N  E + K IS +        +    +  +Y +   K  + IS+L ++      ++  L 
Sbjct: 1092 NALEEQFKEISRMNDHLKGETERQENINNRYKQSSQKKDEVISELHNENDDLSKENDDLT 1151

Query: 666  EQIDALSASKKELALVIENLKLDKEQLYGTIK---DL---ENDKEDIMNKLQNYIQENMD 719
            ++I+ L   K +++ + E+ K + +QL   I+   DL   +ND E++M +  +  +EN D
Sbjct: 1152 KEIEDL---KTKISKLNEDHKKEIKQLLDQIEQKNDLLTQQNDYENLMKENDDLDKENED 1208

Query: 720  LTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRIC 779
            LT + E++ AEK  E L + N   +  +      D   +E    I+N+E E    K    
Sbjct: 1209 LTKENEQLVAEK--ETLCQENERLKKALDDSKIFDEIQKELQDKIDNLEKENDNLKKENE 1266

Query: 780  RLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEK 839
            +++     +E  + + + K   +   +++ +K + +  IQ+    ++     + D   E 
Sbjct: 1267 KIQSLKNALELAKSTFD-KEKSIEDEIRKLEKEHKD--IQKQIFGDKQNEEEEEDLSDEN 1323

Query: 840  QLLEIEHENKELQKKN--QILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQ 897
            ++ +I  E ++L+K    QI + E Q L+  LS  Q +   LV                 
Sbjct: 1324 EMTKIRREVEDLKKDALIQIKVNEIQRLEHELSQAQDNSVPLV----------------- 1366

Query: 898  TQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYV 957
             Q + +  NL++   E++    Q K++++ ++ E   ++E    + K+  + Y K ++  
Sbjct: 1367 -QFQSMADNLEQTVEENK----QLKEKMKLIDNELTNKLEFENSELKIDLDNYSKQLD-- 1419

Query: 958  TQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNAL 1017
               +A  +  K   EN+ +  ++L K   E  D  ++ +  +  +       +I+K+   
Sbjct: 1420 ---DANAKISKLEKENIKLK-DKLEKEESEKSDMIIKYENLKMENAVS---GDIDKIKDQ 1472

Query: 1018 LKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQH 1077
            LK K+ +I+ L  + N    + M  +S+ E+K+ +   K++ + E++++ +++L +  ++
Sbjct: 1473 LKDKETDIVGLEAERN----TLMKKLSELENKVQENDEKIKEI-EDLKKENEELKEQLEN 1527

Query: 1078 NEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXX 1137
            N        + D+ + + + TKL  ++ + + +       ++ M +  N +         
Sbjct: 1528 NNNDVEERLQNDNNMLKREITKLKNKLELSEVDKKKADEGVKTMMEKYNKISEENMLLKH 1587

Query: 1138 XXXXLKVQEEEEFIQE 1153
                L   +EE+  +E
Sbjct: 1588 HIEELSQNKEEKSDKE 1603



 Score = 67.3 bits (157), Expect = 3e-09
 Identities = 194/1052 (18%), Positives = 419/1052 (39%), Gaps = 94/1052 (8%)

Query: 109  KQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNALSVLQVKMKIM 168
            KQ  +L K +   + +               Q+ D+  +SN    K    +  Q +++ +
Sbjct: 1008 KQVNDLKKSNEDLLNQIQSDDSKKTIEDLQKQVNDLK-ISNEYLLKQIQNNDSQAQIEEL 1066

Query: 169  ETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAM 228
            + +  DLQ+K +E ++I++   +                     D  +  T+ QEN    
Sbjct: 1067 KKSNDDLQKKYDENEKILKDLLQENNALEEQFKEISRM-----NDHLKGETERQENINNR 1121

Query: 229  EAEWKDEKQRLLKDIESKDVRISSL-EEANKLLEAARFEISL---EHSK----LAQELEQ 280
              +   +K  ++ ++ +++  +S   ++  K +E  + +IS    +H K    L  ++EQ
Sbjct: 1122 YKQSSQKKDEVISELHNENDDLSKENDDLTKEIEDLKTKISKLNEDHKKEIKQLLDQIEQ 1181

Query: 281  XXXXXXXXXXXXXXLAKQS-IEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIR 339
                          + +   ++   E+ T+  E+   E   + +  ++++     +    
Sbjct: 1182 KNDLLTQQNDYENLMKENDDLDKENEDLTKENEQLVAEKETLCQENERLKKALDDSKIFD 1241

Query: 340  QTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTD 399
            +  KEL++K+  +  E+  +   ++K   L      +N     KS + +   E   +D  
Sbjct: 1242 EIQKELQDKIDNLEKENDNLKKENEKIQSL------KNALELAKSTFDK---EKSIEDEI 1292

Query: 400  KKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQH 459
            +K+ K E   ++  I    ++  ++E +  E +            KD LI Q+++   Q 
Sbjct: 1293 RKLEK-EHKDIQKQIFGDKQNEEEEEDLSDENEMTKIRREVEDLKKDALI-QIKVNEIQR 1350

Query: 460  MEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQL---- 515
            +E     H  +  +D N +  VQ Q   +  ++  + N K L EK+K  + ++T      
Sbjct: 1351 LE-----HELSQAQD-NSVPLVQFQSMADNLEQTVEEN-KQLKEKMKLIDNELTNKLEFE 1403

Query: 516  NDEIDAANKNMIKVKSNHKLKLKQMQKTI----DNFSKVSDSNKEIVRLTEELHHLSQKV 571
            N E+     N  K   +   K+ +++K      D   K      +++   E L   +   
Sbjct: 1404 NSELKIDLDNYSKQLDDANAKISKLEKENIKLKDKLEKEESEKSDMIIKYENLKMENAVS 1463

Query: 572  AELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELH 631
             ++++ K  L+    D        + + KK+ E+EN  +   + I  +E  K +  +   
Sbjct: 1464 GDIDKIKDQLKDKETDIVGLEAERNTLMKKLSELENKVQENDEKIKEIEDLKKENEELKE 1523

Query: 632  ILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQ 691
             L+   ++VE++L + + +   ++      + L E +D   A +    ++ +  K+ +E 
Sbjct: 1524 QLENNNNDVEERLQNDNNMLKREITKLKNKLELSE-VDKKKADEGVKTMMEKYNKISEEN 1582

Query: 692  --LYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEK--------MSAEKISELLAKIN- 740
              L   I++L  +KE+  +K +N + E+  L+  L             +  S+ L  I  
Sbjct: 1583 MLLKHHIEELSQNKEEKSDK-EN-LNESKPLSSGLATPVKSKDSFFGEDSSSDNLFNITQ 1640

Query: 741  -HEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKA 799
             H   S  + Q+ ++ +    + + E  E E+ + K     +  S+  ++ ++Y   R  
Sbjct: 1641 PHSSTSSPRRQYMVEDEFDSNNSHKEE-EEEIDEVKPEKGLINLSLDAIK-QKYERRR-- 1696

Query: 800  DQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILL 859
                S  Q K+    E T +E+E+V+ + V+ D+    +  L EI    K+L +    + 
Sbjct: 1697 ---SSAAQPKKSDEEEQTKEEEEIVSGIEVI-DNLEPPKSPLREI--SEKDLDENFPDVS 1750

Query: 860  EENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIV 919
              N  L+    DM+Q  +  +E A   D   S  + Y        S    I +E Q+  +
Sbjct: 1751 SSNSPLE--NEDMKQ-MSPKIEAAKYPDPKMSPKSIYAVPSSPKRS---MIENEIQSDDL 1804

Query: 920  QKKKEIEDLE-IEFNTQIESAIRDKKVLNEKY----EKNIEYVTQLEAQLQEYKNNIENL 974
            ++    +  E  EFN    S   D  VL        E NIE  + + +      NN EN 
Sbjct: 1805 EQIDSFQSPESSEFNVVPHS--HDSYVLQNNSDTIPEINIEDTSSMHSNSSLVSNNQENK 1862

Query: 975  NMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINN 1034
              N  E  +   E  +  V++++ +  D  EQ        + L+++++ E+I   ++++ 
Sbjct: 1863 EENQNEFPEE--ENQNDLVEEEEQEQHDKEEQ-----ENHDDLVEEEEHEVINEEEEVHG 1915

Query: 1035 AQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKE 1094
             +        + E K    +   E+ EE++    +   + ++      IL+ +  +  +E
Sbjct: 1916 EE--------EEEKKPVDISVSSEHSEEDVAEEEENQFEEEEEGMYQYILINDGSELDEE 1967

Query: 1095 LKETKLTFEMNIPKTEGMIISSTIEPMSDDAN 1126
                 +  E  +   +     + +    D+ N
Sbjct: 1968 KPRRNIVIEEGVESEDAEEDENDVLDQYDNLN 1999



 Score = 60.1 bits (139), Expect = 5e-07
 Identities = 126/635 (19%), Positives = 251/635 (39%), Gaps = 73/635 (11%)

Query: 950  YEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYIN 1009
            Y+K I+     +AQ+QE  + + +L   +++      ++ D   + Q  Q     ++ I 
Sbjct: 25   YQKTIQ---TYQAQVQELTDQVRDLESRLDQSYNTQTQMFDSDTENQSIQQT--LQERIR 79

Query: 1010 EINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSK 1069
            ++++ N+ LK         N +IN+  VS     +   +  AQ   +    E E  R   
Sbjct: 80   QLSQRNSELK---------NSRINSPAVSSTKRSASIANPEAQSAIEKLREENETMRKEN 130

Query: 1070 QLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVD 1129
            +LL +K     LQ +     ++ K +KE   T   N       + S+    M     N  
Sbjct: 131  KLLATK-----LQAIT----EKYKSIKEKDRTLLDNYK-----VASNKFREM----RNKY 172

Query: 1130 XXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHD 1189
                         K++ +++ +    ++Q+Q   LN +  E   K+ ++ T N  L   +
Sbjct: 173  ESNIRQYGQVVDSKMETDQKLVD---LMQQQQNLLNQK-NELEAKLNEVTTNNESLAAKN 228

Query: 1190 VVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVD-QRGFEIAELWKQHLAQREA 1248
               ++Q   L++++E LN +N +L +   E  S+ +SAV   R  + AE   + LA+ E 
Sbjct: 229  KSLEKQYRDLQNQVEDLNNQNIDLQN---EAESAKNSAVKVTRALKKAE---RKLAKNEQ 282

Query: 1249 DFQKTEHELRVQLSAFESKYEQLLDSVQ--SSTQEETNKI-VTMEQVTSLQNKLQDKEEH 1305
              ++ E   +    A E   +QL +  +   S QE+  ++ +    +    NKL      
Sbjct: 283  QIEEHERIHKEHQEAHEESNKQLQECTKLLQSAQEKLKELQLENNDLKKANNKLTRDNTK 342

Query: 1306 LRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQ 1365
            L+N   K+   ++ +E +   I++ +                     ++E Q+  Q  +Q
Sbjct: 343  LQNNVAKHEKSVSMMESMNQSIQNIESE-------------------KSELQNQLQQYQQ 383

Query: 1366 SILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTI 1425
             I    +E   L+K +              +     + +L   L     E  +   +  I
Sbjct: 384  EIAKRLKEIEGLQKQTETLFNKNNTLQNENSALTENLSQLQDNLSKSKKEA-KSLRKQGI 442

Query: 1426 TLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERV 1485
            T  +   E  N +Q +V  +K + D  +E +     +  K +      E+  KE E ++ 
Sbjct: 443  TAAK---EALNFQQNIVALQKSLLDAHHEIDDLRRDVEDK-NSKIQANESRVKELE-DQN 497

Query: 1486 KLIEELNVKITESVS--LNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNL 1543
            +L+E+ N  + E     ++ +  E+NK    EV K   +   L+ Q  ++   N+E+ + 
Sbjct: 498  QLLEDENKDLEEEAQQYISNKEEEMNKKKSNEVKKLQTLIDQLKQQNDQLQQQNNELHDE 557

Query: 1544 QNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNK 1578
                    +K++          Q R  ++    NK
Sbjct: 558  IEQKEEDLAKLEDEKQQIFQQNQQRQLKIKELTNK 592


>UniRef50_UPI00006CDA45 Cluster: hypothetical protein TTHERM_00402150;
            n=1; Tetrahymena thermophila SB210|Rep: hypothetical
            protein TTHERM_00402150 - Tetrahymena thermophila SB210
          Length = 1762

 Score =  186 bits (454), Expect = 3e-45
 Identities = 222/1125 (19%), Positives = 484/1125 (43%), Gaps = 105/1125 (9%)

Query: 505  LKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEEL 564
            ++ A++QI  L +E+   +KN           LK M + I+ F + S   +++  L EE+
Sbjct: 1    MEEAQQQIEDLKNELQKKDKN-----------LKDMTQKIEKFQQDSQEMEQM--LEEEI 47

Query: 565  HHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLE---S 621
                +++ +L++E    +  +    SG+    D   K+ E+E   E   + IS L    S
Sbjct: 48   KIKEEEIEKLQQELEEKEEEIQQLKSGQQDTGDQNVKLEELEKQIEQNNEVISSLNDLIS 107

Query: 622  QKFDLVQELHILQQKY-DEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELAL 680
            ++  LVQ     +Q+Y D++++   +I  LQ  Q+    K+V +E++++ L    K+   
Sbjct: 108  KQIFLVQHTQQKEQEYKDQIDNSSREIKNLQQ-QLKEASKNVGVEQELEKLKNELKDSQS 166

Query: 681  VIENLKLDKEQLYGTIKDLE---NDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLA 737
            +++  K +  Q    I  ++   N KE     L   I+E +  + K EK    KI +L +
Sbjct: 167  LLQKQKEENNQANQAISAMKEEINSKEKATESLSLQIKEQIQNSQKQEKELQIKIQQLES 226

Query: 738  KINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLER 797
            +I +    K + +      ++  +L I+N +SEL K +  I              +SL+ 
Sbjct: 227  EIINSNAKKQEFK----TLLESNNLQIQNNKSELQKKEEHI--------------HSLQE 268

Query: 798  KADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQI 857
            K DQL S LQ  Q      T + D+L     +L +    + K    I+ + K+L+ K + 
Sbjct: 269  KYDQLLSQLQILQND----TSKSDQLKKMQNLLEEKQNEINK----IQQDKKDLETKVEN 320

Query: 858  LLEENQNLQISLSDMQQHYNALVEKANRTDLA----ESESTKYQTQLRD---LESNLKRI 910
            L +   N+ I L++++  + A  E+  ++ ++    E++  K   Q ++   +E + K+I
Sbjct: 321  LNKNIDNISIQLNELKNEF-AQREQGYQSQISSQSQEAQKNKEIIQKKEEQIIELSQKQI 379

Query: 911  THEHQTLIVQKK-------KEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQ 963
              ++Q  ++Q         K+++    E   Q+  A+  +K L  K +   + +  ++ +
Sbjct: 380  QIQNQLQVLQNDTSKSDQLKQVQSTLFEKENQLNQALEVQKELQAKIQDEKKLIENIQKE 439

Query: 964  LQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDE 1023
              + K  + +   N    +K +LEL D+ +Q +Q +     +Q  + +NK N +  Q  +
Sbjct: 440  ADQLKKTLNDKEFN----HKNSLELKDQEIQLKQAEIQKKEQQIEDLLNKQNQIQAQLLK 495

Query: 1024 EIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQI 1083
            ++  L Q+  +          D E ++     K+   E++ + +  Q+    Q N++ Q+
Sbjct: 496  QLQHLLQERQDQIDQIQQSKRDLELQITNLNNKINQFEQKCKDLDLQINSLNQENQKKQV 555

Query: 1084 LVREQDDQIKELK-----ETKL-TFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXX 1137
             + E   +++  +     +T+L   E+   K E       I+ + +    +         
Sbjct: 556  QIEENKKELENKQQIFKSQTELQQKEIKESKAEIQKKQEIIQELQNKEKQLQSQLQIMLQ 615

Query: 1138 XXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQIN 1197
                L  + + E  Q +   ++   +L T  ++  TK ++ +    +L+  +  N+++I 
Sbjct: 616  QLHKLLEERQNEISQVQENKKDIEQRLATLTKDYETKQVEFDETKKQLSDKEQQNKQEIQ 675

Query: 1198 QLKSKLEQLNTENDNLLSTV-AELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHE 1256
            +L  K+     +  NL S   +    +    +  + +E   L  Q+++Q +    K E E
Sbjct: 676  KLSIKVIGYEKDLTNLQSKCQSYYEENQQKTLKLKEYEKKVLDSQNISQEK--ILKME-E 732

Query: 1257 LRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADV 1316
            ++      + +YE+ + + Q    ++  K    +Q+  ++       E ++N   ++   
Sbjct: 733  IQKHCQQLQKQYEEQVQNEQKKLSQQKEKFEEQQQMLEIER--DQLREQIKNFTVQHEQS 790

Query: 1317 INQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILN---INEE 1373
            I Q+     E++  K+                   ++       Q +++ I     I + 
Sbjct: 791  ILQLNEKEEEVDQFKLLLKQLTEEKEREAAKIKTQIQGMQNKIDQGRDELIKKENLIQDL 850

Query: 1374 NAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDE 1433
              ++                  N+AE K   + + L+    ++ +K  E  I     N +
Sbjct: 851  RQEIYSKQSTIDSLQTTIGENQNEAEQKNQLIINSLK---QDLERKQKEVQIL----NTQ 903

Query: 1434 FENVRQQLVEYEKRIEDLTYEKESELAILRLKMHE-NANHYETMQKESEIERV-----KL 1487
            FE  +Q   + E++++D+   KE E+  L  ++++ N     +  KE+E++++     ++
Sbjct: 904  FEQFKQDSEDLEQQLQDMVKSKEDEITELNEQINKLNHQAITSQHKENELQKIQQEKDRI 963

Query: 1488 IEEL---NVKITESVSLNK---QVAELNKALEEEVAKTN-----EMQTALENQEIEIVTL 1536
             ++L   N KI E + + K   +  ++N  L+  +   +      +Q   +  + EI +L
Sbjct: 964  QDQLDLANKKIQEQIQIIKSFFKFYQINNRLKNNMQINSSYYDRNIQDVKDQHQKEISSL 1023

Query: 1537 NDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELL 1581
            N++I+  Q M++    KI  +    +   +   EQLD  + K +L
Sbjct: 1024 NNQISEFQKMIKELQDKINSNEGQQNQENKQNQEQLDLEIEKNIL 1068



 Score =  158 bits (384), Expect = 1e-36
 Identities = 246/1273 (19%), Positives = 546/1273 (42%), Gaps = 79/1273 (6%)

Query: 212  EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271
            +D  Q++ K Q++   ME   ++E +   ++IE     +   EE  + L++ + +   ++
Sbjct: 23   KDMTQKIEKFQQDSQEMEQMLEEEIKIKEEEIEKLQQELEEKEEEIQQLKSGQQDTGDQN 82

Query: 272  SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELL 331
             KL +  +Q              ++KQ       ++ E E K  ++ ++      + +L 
Sbjct: 83   VKLEELEKQIEQNNEVISSLNDLISKQIFLVQHTQQKEQEYKDQIDNSSREIKNLQQQLK 142

Query: 332  E-HLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISR-KSGRNTASKMKSPWS-Q 388
            E   N  + Q  ++L+N+L    +  +     + + +  IS  K   N+  K     S Q
Sbjct: 143  EASKNVGVEQELEKLKNELKDSQSLLQKQKEENNQANQAISAMKEEINSKEKATESLSLQ 202

Query: 389  LSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTL 448
            +  +  N    +K  + +I +LE  I + N    + + ++   +            K+  
Sbjct: 203  IKEQIQNSQKQEKELQIKIQQLESEIINSNAKKQEFKTLLESNNLQIQNNKSELQKKEEH 262

Query: 449  IAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSA 508
            I  LQ ++ Q +    ++   T+  D  ++ K+Q  L+++ N+      +  + +  K  
Sbjct: 263  IHSLQEKYDQLLSQLQILQNDTSKSD--QLKKMQNLLEEKQNE------INKIQQDKKDL 314

Query: 509  EEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEE-LHHL 567
            E ++  LN  ID  +  + ++K+    + +  Q  I + S+ +  NKEI++  EE +  L
Sbjct: 315  ETKVENLNKNIDNISIQLNELKNEFAQREQGYQSQISSQSQEAQKNKEIIQKKEEQIIEL 374

Query: 568  SQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQK---F 624
            SQK  +++ +   LQ      D  + ++S +++K  ++    E + +  + ++ +K    
Sbjct: 375  SQKQIQIQNQLQVLQNDTSKSDQLKQVQSTLFEKENQLNQALEVQKELQAKIQDEKKLIE 434

Query: 625  DLVQELHILQQKYDEVEDKLADISQLQSDQV---CSEI--KSVHLEEQIDALSASKKELA 679
            ++ +E   L++  ++ E    +  +L+  ++    +EI  K   +E+ ++  +  + +L 
Sbjct: 435  NIQKEADQLKKTLNDKEFNHKNSLELKDQEIQLKQAEIQKKEQQIEDLLNKQNQIQAQLL 494

Query: 680  LVIENLKLDK----EQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAE-KISE 734
              +++L  ++    +Q+  + +DLE    ++ NK+  + Q+  DL  ++  ++ E +  +
Sbjct: 495  KQLQHLLQERQDQIDQIQQSKRDLELQITNLNNKINQFEQKCKDLDLQINSLNQENQKKQ 554

Query: 735  LLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYS 794
            +  + N +E    Q  F    ++Q+++  I+  ++E+ K +  I  L+     ++ +   
Sbjct: 555  VQIEENKKELENKQQIFKSQTELQQKE--IKESKAEIQKKQEIIQELQNKEKQLQSQ--- 609

Query: 795  LERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKK 854
            L+    QL   L+E+Q   S+    + ++  RLA L    +  E + +E +   K+L  K
Sbjct: 610  LQIMLQQLHKLLEERQNEISQVQENKKDIEQRLATL---TKDYETKQVEFDETKKQLSDK 666

Query: 855  NQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEH 914
             Q   +E Q L I +   ++    L  K         + T    +      + + I+ E 
Sbjct: 667  EQQNKQEIQKLSIKVIGYEKDLTNLQSKCQSYYEENQQKTLKLKEYEKKVLDSQNISQEK 726

Query: 915  QTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENL 974
               + + +K  + L+ ++  Q+++   ++K L+++ EK  E    LE +  + +  I+N 
Sbjct: 727  ILKMEEIQKHCQQLQKQYEEQVQN---EQKKLSQQKEKFEEQQQMLEIERDQLREQIKNF 783

Query: 975  NMNVE----ELNKMNLELID-KHVQKQQTQSPDYTEQYI-NEINKLNALLKQKDEEIIAL 1028
             +  E    +LN+   E+   K + KQ T+  +     I  +I  +   + Q  +E+I  
Sbjct: 784  TVQHEQSILQLNEKEEEVDQFKLLLKQLTEEKEREAAKIKTQIQGMQNKIDQGRDELIKK 843

Query: 1029 NQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQ 1088
               I + +    S  S  +S     TT  EN  E  Q+    +   KQ  E  Q  V+  
Sbjct: 844  ENLIQDLRQEIYSKQSTIDSLQ---TTIGENQNEAEQKNQLIINSLKQDLERKQKEVQIL 900

Query: 1089 DDQIKELKETKLTFEMNIPKTEGMIIS--STIEPMSDDANNVDXXXXXXXXXXXXL-KVQ 1145
            + Q ++ K+     E  +   + M+ S    I  +++  N ++            L K+Q
Sbjct: 901  NTQFEQFKQDSEDLEQQL---QDMVKSKEDEITELNEQINKLNHQAITSQHKENELQKIQ 957

Query: 1146 EEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETL---NTELTG--HDVVNQEQINQLK 1200
            +E++ IQ++  L  +  +   ++ + + K  Q+      N ++    +D   Q+  +Q +
Sbjct: 958  QEKDRIQDQLDLANKKIQEQIQIIKSFFKFYQINNRLKNNMQINSSYYDRNIQDVKDQHQ 1017

Query: 1201 SKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQ 1260
             ++  LN +       + EL+  I+S   Q+  E     KQ+  Q + + +K        
Sbjct: 1018 KEISSLNNQISEFQKMIKELQDKINSNEGQQNQEN----KQNQEQLDLEIEKN------- 1066

Query: 1261 LSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQI 1320
                E + E+L +++++  +E  NKI   +   S    +Q +++ L N   K  D +  +
Sbjct: 1067 -ILLECQIEELQNNIKNLQREANNKIEQFDNELSTV-LIQSQKQLLENSNLK--DKVQSL 1122

Query: 1321 E-ILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQ-SILNINEENAQLK 1378
            E  +  + +D K                    +R ++Q   ++++Q   L    +N + K
Sbjct: 1123 EKRIGEQSKDYKNQNDRGKKISSDIQEKQSAQIREKDQEILKLKKQVHSLEDQVKNLEFK 1182

Query: 1379 -KSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDS-EIYQKTHEYTITLTQ--RNDEF 1434
             K               V  A  K LEL  +  ++++  + QK    T  L +  ++  F
Sbjct: 1183 IKKEQTNGSNSHQKQIEVYQANQKDLELKVEFLIEENRNLQQKLDAITEDLFEQLKDTRF 1242

Query: 1435 ENVRQ--QLVEYE 1445
             N++Q  Q++E E
Sbjct: 1243 ANIQQLKQVIELE 1255



 Score =  151 bits (365), Expect = 2e-34
 Identities = 252/1264 (19%), Positives = 554/1264 (43%), Gaps = 113/1264 (8%)

Query: 141  LGDVTHLSNTIKEKDNALS-VLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXX 199
            L D+T      ++    +  +L+ ++KI E  I  LQ+++ EK++ I+ + K+       
Sbjct: 22   LKDMTQKIEKFQQDSQEMEQMLEEEIKIKEEEIEKLQQELEEKEEEIQ-QLKSGQQDTGD 80

Query: 200  XXXXXXXXXXXXEDTKQQMTKM-----QENFIAMEAEWKDEKQRLLKDIESKDVR--ISS 252
                        E   + ++ +     ++ F+    + K+++ +   D  S++++     
Sbjct: 81   QNVKLEELEKQIEQNNEVISSLNDLISKQIFLVQHTQQKEQEYKDQIDNSSREIKNLQQQ 140

Query: 253  LEEANK------LLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXL-----AKQSIE 301
            L+EA+K       LE  + E+    S L ++ E+              +     A +S+ 
Sbjct: 141  LKEASKNVGVEQELEKLKNELKDSQSLLQKQKEENNQANQAISAMKEEINSKEKATESLS 200

Query: 302  PSCEEKTEIEEKGSLEI-ANMTELTKKI----ELLEHLNCQIRQTNKELENKLATMGTES 356
               +E+ +  +K   E+   + +L  +I       +     +   N +++N  + +  + 
Sbjct: 201  LQIKEQIQNSQKQEKELQIKIQQLESEIINSNAKKQEFKTLLESNNLQIQNNKSELQKKE 260

Query: 357  KAVSSPSKKGSPLISR-KSGRNTASKMKSPWSQLSS-ETLNQDTDKKINKNEIAK--LEM 412
            + + S  +K   L+S+ +  +N  SK      QL   + L ++   +INK +  K  LE 
Sbjct: 261  EHIHSLQEKYDQLLSQLQILQNDTSKS----DQLKKMQNLLEEKQNEINKIQQDKKDLET 316

Query: 413  VIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNT 472
             +++LNK++ +    ++E             G  + I+    E Q++ E      +    
Sbjct: 317  KVENLNKNIDNISIQLNE---LKNEFAQREQGYQSQISSQSQEAQKNKE-----IIQKKE 368

Query: 473  EDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSA-EEQITQLNDEIDAANKNMIKVKS 531
            E + E+++ Q Q++ +L     D +  D +++++S   E+  QLN  ++   +   K++ 
Sbjct: 369  EQIIELSQKQIQIQNQLQVLQNDTSKSDQLKQVQSTLFEKENQLNQALEVQKELQAKIQD 428

Query: 532  NHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSG 591
              KL ++ +QK  D   K  +  +   + + EL     ++ + E +K   Q+  +  +  
Sbjct: 429  EKKL-IENIQKEADQLKKTLNDKEFNHKNSLELKDQEIQLKQAEIQKKEQQIEDL-LNKQ 486

Query: 592  RMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADIS-QL 650
              I++ + K   ++++L + R   I  ++  K DL  ++  L  K ++ E K  D+  Q+
Sbjct: 487  NQIQAQLLK---QLQHLLQERQDQIDQIQQSKRDLELQITNLNNKINQFEQKCKDLDLQI 543

Query: 651  QSDQVCSEIKSVHLEEQIDALSAS----KKELALVIENLKLDKEQL---YGTIKDLENDK 703
             S    ++ K V +EE    L       K +  L  + +K  K ++      I++L+N +
Sbjct: 544  NSLNQENQKKQVQIEENKKELENKQQIFKSQTELQQKEIKESKAEIQKKQEIIQELQNKE 603

Query: 704  EDIMNKLQNYIQENMDLTDKLE------KMSAEKISELLAKINHEEQSKIQTQFGIDAKI 757
            + + ++LQ  +Q+   L ++ +      + + + I + LA +  + ++K Q +F  + K 
Sbjct: 604  KQLQSQLQIMLQQLHKLLEERQNEISQVQENKKDIEQRLATLTKDYETK-QVEFD-ETKK 661

Query: 758  QERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYT 817
            Q  D   +N + E+ K   ++   E+ +  ++ +  S   +  Q    L+E +K   +  
Sbjct: 662  QLSDKEQQN-KQEIQKLSIKVIGYEKDLTNLQSKCQSYYEENQQKTLKLKEYEKKVLDSQ 720

Query: 818  IQEDELVNRLAVLMDHDRVVEKQLLE-IEHENKELQKKNQILLEENQNLQISLSDMQQHY 876
                E + ++  +  H + ++KQ  E +++E K+L ++ +   E+ Q L+I    +++  
Sbjct: 721  NISQEKILKMEEIQKHCQQLQKQYEEQVQNEQKKLSQQKEKFEEQQQMLEIERDQLREQI 780

Query: 877  NALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQI 936
                 +  ++ L  +E  +   Q + L   LK++T E +    + K +I+ ++ + +   
Sbjct: 781  KNFTVQHEQSILQLNEKEEEVDQFKLL---LKQLTEEKEREAAKIKTQIQGMQNKIDQGR 837

Query: 937  ESAIRDKKVL----NEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKH 992
            +  I+ + ++     E Y K    +  L+  + E +N  E  N  +    K +LE   K 
Sbjct: 838  DELIKKENLIQDLRQEIYSKQ-STIDSLQTTIGENQNEAEQKNQLIINSLKQDLERKQKE 896

Query: 993  VQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQ 1052
            VQ   TQ   + +   +   +L  ++K K++EI  LN++IN  ++++ ++ S ++     
Sbjct: 897  VQILNTQFEQFKQDSEDLEQQLQDMVKSKEDEITELNEQIN--KLNHQAITSQHKE---- 950

Query: 1053 FTTKLENMEEEMQRVSKQL-LDSKQHNEELQIL-----VREQDDQIK-ELKETKLTFEMN 1105
               +L+ +++E  R+  QL L +K+  E++QI+       + ++++K  ++     ++ N
Sbjct: 951  --NELQKIQQEKDRIQDQLDLANKKIQEQIQIIKSFFKFYQINNRLKNNMQINSSYYDRN 1008

Query: 1106 IPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLN 1165
            I   +       I  +++  +                + Q+ +E  Q +  L  +  K  
Sbjct: 1009 IQDVKDQ-HQKEISSLNNQISEFQKMIKELQDKINSNEGQQNQENKQNQEQLDLEIEK-- 1065

Query: 1166 TELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLN---TENDNLLSTVAELRS 1222
              L EC  + +Q    N +   ++ + Q   N+L + L Q      EN NL   V  L  
Sbjct: 1066 NILLECQIEELQNNIKNLQREANNKIEQFD-NELSTVLIQSQKQLLENSNLKDKVQSLEK 1124

Query: 1223 SISSA------VDQRGFEI-AELWKQHLAQ-READ-----FQKTEHELRVQLSAFESKYE 1269
             I          + RG +I +++ ++  AQ RE D      +K  H L  Q+   E K +
Sbjct: 1125 RIGEQSKDYKNQNDRGKKISSDIQEKQSAQIREKDQEILKLKKQVHSLEDQVKNLEFKIK 1184

Query: 1270 QLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIED 1329
            +   +  +S Q++    V       L+ K++   E  RNLQ+K  D I   E L  +++D
Sbjct: 1185 KEQTNGSNSHQKQIE--VYQANQKDLELKVEFLIEENRNLQQK-LDAIT--EDLFEQLKD 1239

Query: 1330 EKVA 1333
             + A
Sbjct: 1240 TRFA 1243



 Score = 85.4 bits (202), Expect = 1e-14
 Identities = 212/1035 (20%), Positives = 430/1035 (41%), Gaps = 110/1035 (10%)

Query: 51   QIKFERAQKCLENAALVSKRIKEHRKATAELLGRPFVPGISESLANTLKQKEILMEKIKQ 110
            + K E   K ++N ++    +K +  A  E   + +   IS       K KEI+ +K +Q
Sbjct: 315  ETKVENLNKNIDNISIQLNELK-NEFAQRE---QGYQSQISSQSQEAQKNKEIIQKKEEQ 370

Query: 111  YKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNALS-VLQVKMKIME 169
              ELS++    I                 QL  V    +T+ EK+N L+  L+V+     
Sbjct: 371  IIELSQKQ---IQIQNQLQVLQNDTSKSDQLKQV---QSTLFEKENQLNQALEVQK---- 420

Query: 170  TTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAME 229
                +LQ KI ++ ++IE   K                    E   +   ++++  I ++
Sbjct: 421  ----ELQAKIQDEKKLIENIQK--------EADQLKKTLNDKEFNHKNSLELKDQEIQLK 468

Query: 230  AEWKDEKQRLLKDIESKDVRISS--LEEANKLLEAARFEI-SLEHSKLAQELEQXXXXXX 286
                 +K++ ++D+ +K  +I +  L++   LL+  + +I  ++ SK   EL+       
Sbjct: 469  QAEIQKKEQQIEDLLNKQNQIQAQLLKQLQHLLQERQDQIDQIQQSKRDLELQITNLNNK 528

Query: 287  XXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELE 346
                          E  C++         L+I ++ +  +K ++      QI +  KELE
Sbjct: 529  I----------NQFEQKCKDL-------DLQINSLNQENQKKQV------QIEENKKELE 565

Query: 347  NKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKI--NK 404
            NK     ++++      K+    I +K       + K    Q   + + Q   K +   +
Sbjct: 566  NKQQIFKSQTELQQKEIKESKAEIQKKQEIIQELQNKEKQLQSQLQIMLQQLHKLLEERQ 625

Query: 405  NEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPS 464
            NEI++++      NK  +++      KD            K   ++  + +++Q ++  S
Sbjct: 626  NEISQVQE-----NKKDIEQRLATLTKDYETKQVEFDETKKQ--LSDKEQQNKQEIQKLS 678

Query: 465  LIHVGTNTEDVNEIAKVQE----------QLKQELNDEIKDVNV-KDLIEKLKSAEEQIT 513
            +  +G   +  N  +K Q           +LK+     +   N+ ++ I K++  ++   
Sbjct: 679  IKVIGYEKDLTNLQSKCQSYYEENQQKTLKLKEYEKKVLDSQNISQEKILKMEEIQKHCQ 738

Query: 514  QLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAE 573
            QL  + +   +N  K  S  K K ++ Q+ ++   +     ++I   T +      ++ E
Sbjct: 739  QLQKQYEEQVQNEQKKLSQQKEKFEEQQQMLE--IERDQLREQIKNFTVQHEQSILQLNE 796

Query: 574  LEEEKGNLQLHLVDYDSGRMIESDVYKKMIE-MENLAETRLKAISLLESQKFDLVQELHI 632
             EEE    +L L      +  E+   K  I+ M+N  +     +   E+   DL QE++ 
Sbjct: 797  KEEEVDQFKLLLKQLTEEKEREAAKIKTQIQGMQNKIDQGRDELIKKENLIQDLRQEIYS 856

Query: 633  LQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQL 692
             Q   D ++  + + +Q +++Q  +++    L++ ++      + L    E  K D E L
Sbjct: 857  KQSTIDSLQTTIGE-NQNEAEQK-NQLIINSLKQDLERKQKEVQILNTQFEQFKQDSEDL 914

Query: 693  YGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFG 752
               ++D+   KED + +L     E ++  +     S  K +E L KI  +E+ +IQ Q  
Sbjct: 915  EQQLQDMVKSKEDEITEL----NEQINKLNHQAITSQHKENE-LQKI-QQEKDRIQDQLD 968

Query: 753  I-DAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQK 811
            + + KIQE+   I+ I+S    Y+    RL+ ++ +  +  Y  +R    +     + QK
Sbjct: 969  LANKKIQEQ---IQIIKSFFKFYQIN-NRLKNNMQI--NSSY-YDRNIQDV---KDQHQK 1018

Query: 812  AYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSD 871
              S    Q  E    +  L D     E Q      ENK+ Q++  + +E+N  L+  + +
Sbjct: 1019 EISSLNNQISEFQKMIKELQDKINSNEGQQ---NQENKQNQEQLDLEIEKNILLECQIEE 1075

Query: 872  MQQHYNALVEKA-NRTDLAESE--STKYQTQLRDLE-SNLKRITHEHQTLIVQKKKEIED 927
            +Q +   L  +A N+ +  ++E  +   Q+Q + LE SNLK      +  I ++ K+ ++
Sbjct: 1076 LQNNIKNLQREANNKIEQFDNELSTVLIQSQKQLLENSNLKDKVQSLEKRIGEQSKDYKN 1135

Query: 928  LEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLE 987
             + +   +I S I++K+    + EK+ E + +L+ Q+   ++ ++NL   +++       
Sbjct: 1136 -QNDRGKKISSDIQEKQSAQIR-EKDQE-ILKLKKQVHSLEDQVKNLEFKIKKEQTNGSN 1192

Query: 988  LIDKHVQKQQTQSPDY---TEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVS 1044
               K ++  Q    D     E  I E   L   L    E++    +    A +  +  V 
Sbjct: 1193 SHQKQIEVYQANQKDLELKVEFLIEENRNLQQKLDAITEDLFEQLKDTRFANIQQLKQVI 1252

Query: 1045 DYE--SKLAQFTTKL 1057
            + E   K   F  KL
Sbjct: 1253 ELEIVKKTGSFGFKL 1267


>UniRef50_A2DKE3 Cluster: Viral A-type inclusion protein, putative;
            n=1; Trichomonas vaginalis G3|Rep: Viral A-type inclusion
            protein, putative - Trichomonas vaginalis G3
          Length = 2870

 Score =  186 bits (454), Expect = 3e-45
 Identities = 295/1503 (19%), Positives = 645/1503 (42%), Gaps = 132/1503 (8%)

Query: 143  DVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXX 202
            +VT+L++ + + D   S L  ++         L++K++E   IIE K             
Sbjct: 1230 EVTYLNDILNQLDIKNSDLAQQIAEHRQGYEILKQKLDEASHIIEEKESNVFEEKQQTNE 1289

Query: 203  XXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEA 262
                        ++++T+   +   ++++  DE ++ L++    +++I    E  ++   
Sbjct: 1290 VISQAKAKISRLERKLTESNSSNKDLQSK-VDELKKKLQESSENEIKIKQNTEQMRIEME 1348

Query: 263  ARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMT 322
             R     E  +L ++L +              L   +++ S +++TE++ K   +  +  
Sbjct: 1349 KRIT---EQEQLKKQLTELQTNNINNQKQINDL-NNTLKISEKQRTELQVKFDEQTKSNK 1404

Query: 323  ELT-KKIELLEHLNCQIRQTNKELENKLAT---MGTESKAVSSPSKKGSPLISRKSGRNT 378
            E+  +K + +  LN +I +   ++E + A    + TE  +++    K    I   + + T
Sbjct: 1405 EIVDQKQQQIYSLNNEISKMKADIEKQNALNNDLNTEKSSLNVKIVKFESEIKSLNEKLT 1464

Query: 379  ASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEK--DTXXX 436
              K     SQL  + L ++   ++   E++ L+     L     +KE  + ++  +    
Sbjct: 1465 NMKEIIANSQLEKKKLEEEIKSRVK--ELSNLQEENAKLLTSSHEKEITMQKEKFENETQ 1522

Query: 437  XXXXXXXGKDTLIAQLQ--LEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIK 494
                    K   I++L+  L  ++      L  +      + +  ++ E+  +E + ++K
Sbjct: 1523 KMKKEIEEKTANISELEKALSDKERNHKNLLSKIQKKYSQLEDKLEIAEEKLEESDKKVK 1582

Query: 495  DVNVKDLIEKLKSAEEQI-TQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDS 553
            D+  K++I   K  + Q+  + N  I+  NK   + K+N  L+LK ++  I+N  +  +S
Sbjct: 1583 DL--KNIITLHKQNQVQMENEHNQLINDMNKQHDQEKNNLSLQLKSLENQIENLIQEKES 1640

Query: 554  NK-EIVRLTEELHHLSQKVAELEE--EKGNLQLHLVDYDSGRM---IESDVYKKMIEMEN 607
             + EI  +  +   + Q + +     +K ++++  +     ++   IES + +++ E EN
Sbjct: 1641 YETEISTVYGDRDSMKQALEKASAFIQKKSIKIEKMKKQMSQVKVTIES-MNEELSEKEN 1699

Query: 608  LAETRLKAISLLESQKFDLVQE---LHILQQKYDEVEDKLADISQLQS--DQVCSEIKSV 662
              E   K  + L  QK  + +    +  L  +  E + KL ++  L+    Q+   I+ +
Sbjct: 1700 QIEELQKLTNRLGKQKVQITETNDAISKLNAEIAEKDQKLFEMEVLKKKISQLTETIEKL 1759

Query: 663  --HLEEQIDALSASKKELAL---VIENLKLDKEQLYGTIKDLEND-KEDIMNKLQNYIQE 716
               LE   +     K EL     +IE+LK  KE +   + DLE    E+I   LQ+ I E
Sbjct: 1760 TKDLENSQNETINFKNELNYTKKLIEDLKQQKEDIQNEL-DLEKQHSEEISKTLQSKIDE 1818

Query: 717  NMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKS 776
            N     K+++++ + IS  L K +   + K+     +++ I+ ++  IE++++ L   K 
Sbjct: 1819 NTSQNVKIQELNEKTIS--LQKESDSYKLKVDE---LNSDIKRKNAMIEDMKNHLISQKV 1873

Query: 777  RICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRV 836
                + +S   M+ +  SL  +  +  + + E Q+  ++  ++  +   +L +     +V
Sbjct: 1874 ENETIYKSNNQMKAKIESLYNEIKENKAKIDEYQRESAKVDVERTQF--QLTIKDYEMKV 1931

Query: 837  VEKQLLEIEHENK--ELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESEST 894
             ++  L +  E K    QK+N +L +E +  +     + Q  ++ ++   +      E  
Sbjct: 1932 KDENNLRLTTEEKLSNAQKENDLLKKEIEKKENDNQLLSQSKDSSLQTVTQLKSLVEEKE 1991

Query: 895  KYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQ---IESAIRDKKVLNEKYE 951
            K    L    ++ +   HE +    + K EIED+    +T    +++   DK  L ++  
Sbjct: 1992 KQIASLNKKVADYESTIHESEIYQTKTKLEIEDITKSKSTLQQLLDTISNDKSNLEKQIL 2051

Query: 952  KNIEYVTQLEAQLQEYKNNIENLNM----NVEELNKMNLELIDKHVQKQQTQSPDYTEQY 1007
                 V+ L AQ+   + + + L +    N  ++N +N + I +  +  QT+S +  + +
Sbjct: 2052 DQKSTVSLLTAQISNLQESEQKLKLTQIQNNTQINDLNNK-ISEMTKTDQTKS-EIIQNH 2109

Query: 1008 INEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVS----DYESK---LAQFTTKLENM 1060
             N+I++L   L  K+ E+   N++I N +    S++     + ++K   L  + TK ENM
Sbjct: 2110 QNKIHELELQLLDKNNELNNANKEIENIKSQTESIIQKTAFEIQNKTEILNNYETKFENM 2169

Query: 1061 EEEMQRVSKQLLDSKQHNEELQILVREQDDQI--KELKETKLTFEMNIPKTEGMIISSTI 1118
            +++  + +  + D  + + +L+  V   ++Q+   ++K   LT E+N  + +       I
Sbjct: 2170 KKQNAKAAVTINDMTKSSSDLRKHVNLLENQLFDSKMKIENLTKELNESQNK-------I 2222

Query: 1119 EPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQL 1178
            + M+   N                + +++E   +E +  Q +  K+ TE  E  +KI+  
Sbjct: 2223 QSMTKQINE-SRAFSSTLQTKLDRESKQKESLQRELNFTQTELTKIQTEASEYKSKILHT 2281

Query: 1179 ETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAEL 1238
              + + +      N   + + K K E+    N   L T   L   ++S+  ++  E    
Sbjct: 2282 SEMESAMQ-----NSYSLIEEKLKSEENKRRNLERLITDMRLTRDVNSSPKKQEIE---- 2332

Query: 1239 WKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNK 1298
                              L++ L   E++ ++L++ ++  T  E N ++  ++++ L + 
Sbjct: 2333 -----------------SLKINLQNLENENDKLINEIK--TLNEKN-VLLQQEISKLSSD 2372

Query: 1299 LQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXX--------- 1349
            LQ+KE+  ++L +K  D+I++I  L+++I+D K+                          
Sbjct: 2373 LQEKEKSEKSLLQKQNDLISEISKLKNDIKDHKINLSQSTSSLKKDISTKAKQIEQSKDE 2432

Query: 1350 -XDLRTENQSYK----------QMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDA 1398
              +L+TEN S K          Q  E S+   N+   Q+K S              +N  
Sbjct: 2433 LNNLQTENNSLKKKIQNLEAVLQDTEDSLAQSNQSQRQIKASYDLLNNKFEENQVLLNSK 2492

Query: 1399 EAKVLELTHQLELKDSEIYQKTHEYTITLTQR-NDEFENVRQQLVEYEKRIEDLTYEKES 1457
            + ++  LT+++  K+ E+ +KT    I + +R   +   + Q + E + ++E L  E E 
Sbjct: 2493 QKEIERLTNEVSDKEKEL-EKTKSELINIQERIRSDSSKLNQDINEKQTKLESLNIELEK 2551

Query: 1458 ELAI---LRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEE 1514
               I   L  K++   +  +++   ++ +    I + N + +    L K    L K LEE
Sbjct: 2552 MRNINRELTSKVNSLTSQLQSIADSNQKDINTYISQYNEEKSTRKELEKSNETLKKKLEE 2611

Query: 1515 EVAKTNEMQTALENQEIEIVTLNDEITNLQNMV--RASSSKIQKHVSFAS----DTKQGR 1568
            +V +   +   + + +  I  L  E+T  Q  +  +     +QK V+  S    D +Q  
Sbjct: 2612 KVKENKNLSVKITSLKTNIEELQIEVTRTQRTLVPKNQLESLQKSVNEMSRKLDDAQQNL 2671

Query: 1569 DEQ 1571
             EQ
Sbjct: 2672 AEQ 2674



 Score =  166 bits (404), Expect = 4e-39
 Identities = 281/1485 (18%), Positives = 637/1485 (42%), Gaps = 123/1485 (8%)

Query: 147  LSNTIKEKDNALSVLQVKMK-IMETTILD--LQEKINEKDQIIEAKNKATTXXXXXXXXX 203
            L N  +  ++ +S LQ ++K I + T L   ++E+  E DQ+ +   K  T         
Sbjct: 658  LKNDNESANHTISALQEEIKKISDNTDLTRKIEEQEKEVDQLRKYNEKLETTISSSKQQK 717

Query: 204  XXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAA 263
                    +  KQ + K+ +  I+  A       ++  +    ++   +  E  KL EAA
Sbjct: 718  EEMLHNQNKALKQMIFKLAKE-ISPNAVHSTSFNKMADEF---NMMSQTFNETMKLKEAA 773

Query: 264  RFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTE 323
              ++    SK+     +               A   ++     + +  +K   ++AN TE
Sbjct: 774  TNQLKRIDSKVYGITSRYNIETVDDTVK----ALTELDNLLNIEKQRTQKNLDDLANKTE 829

Query: 324  -LTKKIELLEHLNCQIRQTNKELENKLATM-GTES--KAVSSPSKKGSPLISRKSGRNTA 379
             L  +I+ L+ +N  +   NK+ + ++  + G E   + ++        LI++    N  
Sbjct: 830  DLMDEIDSLQSVNVSLTDQNKKQQIEIIRLQGIERSVEGLNEDLNSAYQLINQYELANQN 889

Query: 380  SKMKSPWSQLSSETLNQDTDKKINK-----NEIAKLEMVIQSLNKDLVDKEYVISEKDTX 434
            S+       +  +   +D  K+I K     NE+  ++    SL K + D    I E +  
Sbjct: 890  SEYAQQMKFIKKKL--KDKQKQIQKYKSSVNELLDVQSENNSLKKQISDLNENIREMNGA 947

Query: 435  XXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTE-DVNEIAKVQEQLKQELNDEI 493
                       D L  Q +LE +  +   SL+      + D   + K  ++LK+  N+E 
Sbjct: 948  LKAANKKLQSLDKL-HQRKLEMEDQIS--SLMTACRQLQMDKESLQKKVDELKKS-NEE- 1002

Query: 494  KDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKS----------NHKLKLKQMQKT 543
            KD  ++   +KL S  + + Q    I+ AN    K  +          N   ++++M+K 
Sbjct: 1003 KDDALESYRDKLNSQIDILGQSQSIIENANDKSRKDSNAIQELKEKLINSDKEIEKMKKE 1062

Query: 544  IDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMI 603
            ++++   + SNKE       L  L QK+ E+       + H+   D+   + +D+   + 
Sbjct: 1063 MNDYENTNKSNKE------NLLKLQQKIIEVTRTVNPTENHVRVSDNVSQLLNDLDLIVK 1116

Query: 604  EMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVH 663
               +  +T  +   +++    + +     L         KL  +S+  ++++ + + +  
Sbjct: 1117 AFSDKDKTINEIKGVIDKNNNEFISFKSNLSNIISSFSQKL--VSETDNNKLLN-LTNDF 1173

Query: 664  LEEQIDALSASKKELALVIEN-------LKLDKEQLYGTIKDLENDKEDIMNKLQNYIQE 716
            ++ Q+D ++  K ++  +I+N       L   + +L   ++++ ++ E   NKL + +  
Sbjct: 1174 VKSQVDQINEIKSQIVQIIKNSSTYKPTLSSPQNELLDILREIISEHEVTENKLGSEVTY 1233

Query: 717  NMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAK--IQERDLYI----ENIESE 770
              D+ ++L+  +++ +++ +A+  H +  +I  Q   +A   I+E++  +    +     
Sbjct: 1234 LNDILNQLDIKNSD-LAQQIAE--HRQGYEILKQKLDEASHIIEEKESNVFEEKQQTNEV 1290

Query: 771  LSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVL 830
            +S+ K++I RLE  +         L+ K D+L   LQE  +   +     +++   +   
Sbjct: 1291 ISQAKAKISRLERKLTESNSSNKDLQSKVDELKKKLQESSENEIKIKQNTEQMRIEMEKR 1350

Query: 831  MDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQIS---LSDMQQHYNALVEKANRTD 887
            +     ++KQL E++  N   QK+   L   N  L+IS    +++Q  ++    K+N+  
Sbjct: 1351 ITEQEQLKKQLTELQTNNINNQKQINDL---NNTLKISEKQRTELQVKFDEQT-KSNKEI 1406

Query: 888  LAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLN 947
            + + +   Y   L +  S +K    +   L      E   L ++   + ES I   K LN
Sbjct: 1407 VDQKQQQIYS--LNNEISKMKADIEKQNALNNDLNTEKSSLNVKI-VKFESEI---KSLN 1460

Query: 948  EKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQY 1007
            EK     E +   + + ++ +  I++    +  L + N +L+    +K+ T      E++
Sbjct: 1461 EKLTNMKEIIANSQLEKKKLEEEIKSRVKELSNLQEENAKLLTSSHEKEITMQK---EKF 1517

Query: 1008 INEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRV 1067
             NE  K+   +++K   I  L + +++ + ++ +++S  + K +Q   KLE  EE+++  
Sbjct: 1518 ENETQKMKKEIEEKTANISELEKALSDKERNHKNLLSKIQKKYSQLEDKLEIAEEKLEES 1577

Query: 1068 SKQLLDSKQ---HNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDD 1124
             K++ D K     +++ Q+ +  + +Q+      +   E N    +   + + IE +  +
Sbjct: 1578 DKKVKDLKNIITLHKQNQVQMENEHNQLINDMNKQHDQEKNNLSLQLKSLENQIENLIQE 1637

Query: 1125 ANNVDXXXXXXXXXXXXLK--VQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLN 1182
              + +            +K  +++   FIQ++S+  E+  K  ++++      + +E++N
Sbjct: 1638 KESYETEISTVYGDRDSMKQALEKASAFIQKKSIKIEKMKKQMSQVK------VTIESMN 1691

Query: 1183 TELTGHDVVNQ-EQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQ 1241
             EL+  +  NQ E++ +L ++L +   +       +++L + I+   DQ+ FE+ E+ K+
Sbjct: 1692 EELSEKE--NQIEELQKLTNRLGKQKVQITETNDAISKLNAEIAEK-DQKLFEM-EVLKK 1747

Query: 1242 HLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIV--TMEQVTSLQNKL 1299
             ++Q     +K   +L       E+   + ++    +    T K++    +Q   +QN+L
Sbjct: 1748 KISQLTETIEKLTKDL-------ENSQNETINF--KNELNYTKKLIEDLKQQKEDIQNEL 1798

Query: 1300 ----QDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTE 1355
                Q  EE  + LQ K  +  +Q  +   E+ ++ ++                 D++ +
Sbjct: 1799 DLEKQHSEEISKTLQSKIDENTSQ-NVKIQELNEKTISLQKESDSYKLKVDELNSDIKRK 1857

Query: 1356 NQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSE 1415
            N   + M+   +++   EN  + KS+             + + +AK+ E  +Q E    +
Sbjct: 1858 NAMIEDMKNH-LISQKVENETIYKSNNQMKAKIESLYNEIKENKAKIDE--YQRESAKVD 1914

Query: 1416 IYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYET 1475
            + ++T ++ +T+     + ++     +  E+++ +   +KE++L    ++  EN N   +
Sbjct: 1915 V-ERT-QFQLTIKDYEMKVKDENNLRLTTEEKLSNA--QKENDLLKKEIEKKENDNQLLS 1970

Query: 1476 MQKESEIERVKLIEEL-NVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIV 1534
              K+S ++ V  ++ L   K  +  SLNK+VA+    + E  ++  + +T LE +  +I 
Sbjct: 1971 QSKDSSLQTVTQLKSLVEEKEKQIASLNKKVADYESTIHE--SEIYQTKTKLEIE--DIT 2026

Query: 1535 TLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKE 1579
                 +  L + +    S ++K +     T      Q+ N    E
Sbjct: 2027 KSKSTLQQLLDTISNDKSNLEKQILDQKSTVSLLTAQISNLQESE 2071



 Score =  165 bits (400), Expect = 1e-38
 Identities = 300/1576 (19%), Positives = 661/1576 (41%), Gaps = 138/1576 (8%)

Query: 90   ISESLANTLKQKEILMEKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSN 149
            + E L N+ K+ E + +++  Y+  +K +   +++                   V    N
Sbjct: 1045 LKEKLINSDKEIEKMKKEMNDYENTNKSNKENLLKLQQKIIEVTRT--------VNPTEN 1096

Query: 150  TIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKA--TTXXXXXXXXXXXXX 207
             ++  DN   +L   + ++     D  + INE   +I+  N    +              
Sbjct: 1097 HVRVSDNVSQLLN-DLDLIVKAFSDKDKTINEIKGVIDKNNNEFISFKSNLSNIISSFSQ 1155

Query: 208  XXXXEDTKQQMTKMQENFIAMEAEWKDE-KQRLLKDIESKDVRISSLEEA-NKLLEAARF 265
                E    ++  +  +F+  + +  +E K ++++ I++      +L    N+LL+  R 
Sbjct: 1156 KLVSETDNNKLLNLTNDFVKSQVDQINEIKSQIVQIIKNSSTYKPTLSSPQNELLDILR- 1214

Query: 266  EISLEH----SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEE---KTEIEEKGSLEI 318
            EI  EH    +KL  E+                LA+Q  E        K +++E   +  
Sbjct: 1215 EIISEHEVTENKLGSEVTYLNDILNQLDIKNSDLAQQIAEHRQGYEILKQKLDEASHIIE 1274

Query: 319  ANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNT 378
               + + ++ +    +  Q +     LE KL    + +K + S   +    +   S    
Sbjct: 1275 EKESNVFEEKQQTNEVISQAKAKISRLERKLTESNSSNKDLQSKVDELKKKLQESSENEI 1334

Query: 379  ASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYV--ISEKDTXXX 436
              K+K    Q+  E   + T+++  K ++ +L+    +  K + D      ISEK     
Sbjct: 1335 --KIKQNTEQMRIEMEKRITEQEQLKKQLTELQTNNINNQKQINDLNNTLKISEKQRTEL 1392

Query: 437  XXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQ--LKQELNDEIK 494
                    K    +  ++  Q+  +  SL     N E     A +++Q  L  +LN E  
Sbjct: 1393 QVKFDEQTK----SNKEIVDQKQQQIYSL-----NNEISKMKADIEKQNALNNDLNTEKS 1443

Query: 495  DVNVK--DLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKV-- 550
             +NVK      ++KS  E++T + + I  +     K++   K ++K++    +  +K+  
Sbjct: 1444 SLNVKIVKFESEIKSLNEKLTNMKEIIANSQLEKKKLEEEIKSRVKELSNLQEENAKLLT 1503

Query: 551  SDSNKEIVRLTEELHHLSQKVA-ELEEEKGN---LQLHLVDYDSG-RMIESDVYKKMIEM 605
            S   KEI    E+  + +QK+  E+EE+  N   L+  L D +   + + S + KK  ++
Sbjct: 1504 SSHEKEITMQKEKFENETQKMKKEIEEKTANISELEKALSDKERNHKNLLSKIQKKYSQL 1563

Query: 606  ENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLE 665
            E+  E   + +   + +  DL   + + +Q   ++E+        + +Q+ +++   H +
Sbjct: 1564 EDKLEIAEEKLEESDKKVKDLKNIITLHKQNQVQMEN--------EHNQLINDMNKQHDQ 1615

Query: 666  EQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQN---YIQENMDLTD 722
            E+ + LS   K L   IENL  +KE     I  +  D++ +   L+    +IQ+     +
Sbjct: 1616 EK-NNLSLQLKSLENQIENLIQEKESYETEISTVYGDRDSMKQALEKASAFIQKKSIKIE 1674

Query: 723  KLEK-MSAEKIS-ELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICR 780
            K++K MS  K++ E + +   E++++I+    +  ++ ++ + I      +SK  + I  
Sbjct: 1675 KMKKQMSQVKVTIESMNEELSEKENQIEELQKLTNRLGKQKVQITETNDAISKLNAEIAE 1734

Query: 781  LEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQ 840
             ++ +  ME     L++K  QL   +++  K        ++E +N    L    +++E  
Sbjct: 1735 KDQKLFEME----VLKKKISQLTETIEKLTKDLEN---SQNETINFKNELNYTKKLIEDL 1787

Query: 841  LLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQL 900
              + E    EL  + Q   E ++ LQ  + +       + E   +T   + ES  Y+ ++
Sbjct: 1788 KQQKEDIQNELDLEKQHSEEISKTLQSKIDENTSQNVKIQELNEKTISLQKESDSYKLKV 1847

Query: 901  RDLESNLKR---ITHEHQTLIVQKKKEIEDL---EIEFNTQIESA---IRDKKVLNEKYE 951
             +L S++KR   +  + +  ++ +K E E +     +   +IES    I++ K   ++Y+
Sbjct: 1848 DELNSDIKRKNAMIEDMKNHLISQKVENETIYKSNNQMKAKIESLYNEIKENKAKIDEYQ 1907

Query: 952  KNIEYV----TQLEAQLQEYKNNIE---NLNMNVEE-LNKMNLE--LIDKHVQKQQTQSP 1001
            +    V    TQ +  +++Y+  ++   NL +  EE L+    E  L+ K ++K++  + 
Sbjct: 1908 RESAKVDVERTQFQLTIKDYEMKVKDENNLRLTTEEKLSNAQKENDLLKKEIEKKENDNQ 1967

Query: 1002 ---DYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLE 1058
                  +  +  + +L +L+++K+++I +LN+K+      Y S +  +ES++ Q  TKLE
Sbjct: 1968 LLSQSKDSSLQTVTQLKSLVEEKEKQIASLNKKV----ADYESTI--HESEIYQTKTKLE 2021

Query: 1059 NME-EEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETK--LTFEM-NIPKTEGMII 1114
              +  + +   +QLLD+  +++         + QI + K T   LT ++ N+ ++E  + 
Sbjct: 2022 IEDITKSKSTLQQLLDTISNDKS------NLEKQILDQKSTVSLLTAQISNLQESEQKLK 2075

Query: 1115 SSTIEPMS--DDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSV-LQEQSAKLNTELQEC 1171
             + I+  +  +D NN              + +Q  +  I E  + L +++ +LN   +E 
Sbjct: 2076 LTQIQNNTQINDLNNKISEMTKTDQTKSEI-IQNHQNKIHELELQLLDKNNELNNANKEI 2134

Query: 1172 YTKIIQLETLNTELTGHDVVNQEQI-NQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQ 1230
                 Q E++  + T  ++ N+ +I N  ++K E +  +N     T+ ++  S S   D 
Sbjct: 2135 ENIKSQTESI-IQKTAFEIQNKTEILNNYETKFENMKKQNAKAAVTINDMTKSSS---DL 2190

Query: 1231 RGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTME 1290
            R  +   L +  L   +   +    EL    +  +S  +Q+ +S   S+  +T      +
Sbjct: 2191 R--KHVNLLENQLFDSKMKIENLTKELNESQNKIQSMTKQINESRAFSSTLQTKLDRESK 2248

Query: 1291 QVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXX 1350
            Q  SLQ +L   +  L  +Q + ++  ++I +  SE+E                      
Sbjct: 2249 QKESLQRELNFTQTELTKIQTEASEYKSKI-LHTSEMESAMQNSYSLIEEKLKSEENKRR 2307

Query: 1351 DLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLE 1410
            +L       +  ++ +     +E   LK +              +     K + L  ++ 
Sbjct: 2308 NLERLITDMRLTRDVNSSPKKQEIESLKINLQNLENENDKLINEIKTLNEKNVLLQQEIS 2367

Query: 1411 LKDSEIYQKTHEYTITLTQRND---EFENVRQQLVEYEKRIEDLTYEKESELAILRLKMH 1467
               S++ +K       L ++ND   E   ++  + +++  +   T   + +++    ++ 
Sbjct: 2368 KLSSDLQEKEKSEKSLLQKQNDLISEISKLKNDIKDHKINLSQSTSSLKKDISTKAKQIE 2427

Query: 1468 ENANHYETMQKESEIERVKL------IEELNVKITESVSLNKQVAE----LNKALEEEVA 1517
            ++ +    +Q E+   + K+      +++    + +S    +Q+      LN   EE   
Sbjct: 2428 QSKDELNNLQTENNSLKKKIQNLEAVLQDTEDSLAQSNQSQRQIKASYDLLNNKFEENQV 2487

Query: 1518 KTNEMQTALE-------NQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDE 1570
              N  Q  +E       ++E E+     E+ N+Q  +R+ SSK+ + ++      +  + 
Sbjct: 2488 LLNSKQKEIERLTNEVSDKEKELEKTKSELINIQERIRSDSSKLNQDINEKQTKLESLNI 2547

Query: 1571 QLD--NTMNKELLDAV 1584
            +L+    +N+EL   V
Sbjct: 2548 ELEKMRNINRELTSKV 2563



 Score =  156 bits (379), Expect = 4e-36
 Identities = 284/1453 (19%), Positives = 599/1453 (41%), Gaps = 115/1453 (7%)

Query: 149  NTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXX 208
            N+ KE      +  ++  +   TIL LQ+  N+KDQ  + K                   
Sbjct: 525  NSFKENQEKFRISLME-NVTNQTILPLQQSNNDKDQ--QIKELMNQIKLIKDKQDEVESK 581

Query: 209  XXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEIS 268
               +D  QQM K+ +    +E E K  K   L    ++D +          ++A   ++ 
Sbjct: 582  NKAKD--QQMKKLIKE---LEKEQKKNKDLTLTIANAEDPK-----HIQTQMQARIDDLQ 631

Query: 269  LEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKI 328
             E S L QE++Q              L K   E +    + ++E+   +I++ T+LT+KI
Sbjct: 632  SEISNLKQEIQQNEQKYQNLKKENKSL-KNDNESANHTISALQEE-IKKISDNTDLTRKI 689

Query: 329  ELLEHLNCQIRQTNKELENKLATMGTE-SKAVSSPSKKGSPLISRKSGRNTASKMKSPWS 387
            E  E    Q+R+ N++LE  +++   +  + + + +K    +I + +   + + + S   
Sbjct: 690  EEQEKEVDQLRKYNEKLETTISSSKQQKEEMLHNQNKALKQMIFKLAKEISPNAVHSTSF 749

Query: 388  QLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDT 447
               ++  N  +      NE  KL+    +  K +  K Y I+ +              + 
Sbjct: 750  NKMADEFNMMSQ---TFNETMKLKEAATNQLKRIDSKVYGITSRYNIETVDDTVKALTE- 805

Query: 448  LIAQLQLEHQQHMEGPSLIHVGTNTED-VNEIAKVQEQLKQELNDEIKDVNVKDLIE--K 504
            L   L +E Q+  +  +L  +   TED ++EI  +     Q +N  + D N K  IE  +
Sbjct: 806  LDNLLNIEKQRTQK--NLDDLANKTEDLMDEIDSL-----QSVNVSLTDQNKKQQIEIIR 858

Query: 505  LKSAEEQITQLNDEIDAANK--NMIKVKSNH----------KLKLKQMQKTIDNFSKVSD 552
            L+  E  +  LN+++++A +  N  ++ + +          K KLK  QK I    K   
Sbjct: 859  LQGIERSVEGLNEDLNSAYQLINQYELANQNSEYAQQMKFIKKKLKDKQKQI---QKYKS 915

Query: 553  SNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETR 612
            S  E++ +  E + L +++++L E    +   L   +        ++++ +EME+   + 
Sbjct: 916  SVNELLDVQSENNSLKKQISDLNENIREMNGALKAANKKLQSLDKLHQRKLEMEDQISSL 975

Query: 613  LKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALS 672
            + A   L+  K  L +++  L++  +E +D L       + Q+    +S  + E  +A  
Sbjct: 976  MTACRQLQMDKESLQKKVDELKKSNEEKDDALESYRDKLNSQIDILGQSQSIIE--NAND 1033

Query: 673  ASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKI 732
             S+K+ +  I+ L   KE+L  + K++E  K++ MN  +N  + N +   KL++   E  
Sbjct: 1034 KSRKD-SNAIQEL---KEKLINSDKEIEKMKKE-MNDYENTNKSNKENLLKLQQKIIEVT 1088

Query: 733  SELLAKINH----EEQSKIQTQFGIDAK-IQERDLYIENIESELSKYKSRICRLEESIA- 786
              +    NH    +  S++     +  K   ++D  I  I+  + K  +     + +++ 
Sbjct: 1089 RTVNPTENHVRVSDNVSQLLNDLDLIVKAFSDKDKTINEIKGVIDKNNNEFISFKSNLSN 1148

Query: 787  VMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEH 846
            ++      L  + D     L            Q +E+ +++  ++ +    +  L   ++
Sbjct: 1149 IISSFSQKLVSETDN-NKLLNLTNDFVKSQVDQINEIKSQIVQIIKNSSTYKPTLSSPQN 1207

Query: 847  ENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKAN--RTDLAE--SESTKYQTQLRD 902
            E  ++ ++   ++ E++  +  L     + N ++ + +   +DLA+  +E  +    L+ 
Sbjct: 1208 ELLDILRE---IISEHEVTENKLGSEVTYLNDILNQLDIKNSDLAQQIAEHRQGYEILKQ 1264

Query: 903  LESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEA 962
                   I  E ++ + ++K++  ++  +   +I    R     N   +     V +L+ 
Sbjct: 1265 KLDEASHIIEEKESNVFEEKQQTNEVISQAKAKISRLERKLTESNSSNKDLQSKVDELKK 1324

Query: 963  QLQEYKNNIENLNMNVEELN-KMNLELID-KHVQKQQTQSPDYTEQYINEINKLNALLKQ 1020
            +LQE   N   +  N E++  +M   + + + ++KQ T+          +IN LN  LK 
Sbjct: 1325 KLQESSENEIKIKQNTEQMRIEMEKRITEQEQLKKQLTELQTNNINNQKQINDLNNTLKI 1384

Query: 1021 KDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEE 1080
             +++   L  K +    S   +V   + ++     ++  M+ ++++ +    D       
Sbjct: 1385 SEKQRTELQVKFDEQTKSNKEIVDQKQQQIYSLNNEISKMKADIEKQNALNNDLNTEKSS 1444

Query: 1081 LQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXX 1140
            L + + + + +IK L E KLT  M        +    +E   +  + V            
Sbjct: 1445 LNVKIVKFESEIKSLNE-KLT-NMKEIIANSQLEKKKLE--EEIKSRVKELSNLQEENAK 1500

Query: 1141 XLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLK 1200
             L    E+E   ++   + ++ K+  E++E   K   +  L   L+  +  ++  +++++
Sbjct: 1501 LLTSSHEKEITMQKEKFENETQKMKKEIEE---KTANISELEKALSDKERNHKNLLSKIQ 1557

Query: 1201 SKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQ 1260
             K  QL    D L     +L  S     D +   I  L KQ+  Q E      EH     
Sbjct: 1558 KKYSQL---EDKLEIAEEKLEESDKKVKDLK--NIITLHKQNQVQME-----NEHN---- 1603

Query: 1261 LSAFESKYEQLLDSVQSSTQEETNKIVTMEQV-TSLQNKLQDKEEHLRNLQEKYADVINQ 1319
                    + + D  +   QE+ N  + ++ +   ++N +Q+KE +   +   Y D  + 
Sbjct: 1604 --------QLINDMNKQHDQEKNNLSLQLKSLENQIENLIQEKESYETEISTVYGDRDSM 1655

Query: 1320 IEIL-RSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLK 1378
             + L ++    +K +                 +   E  S K+ Q + +  +     + K
Sbjct: 1656 KQALEKASAFIQKKSIKIEKMKKQMSQVKVTIESMNEELSEKENQIEELQKLTNRLGKQK 1715

Query: 1379 KSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVR 1438
                            + + + K+ E+   L+ K S++ +   + T  L    +E  N +
Sbjct: 1716 VQITETNDAISKLNAEIAEKDQKLFEM-EVLKKKISQLTETIEKLTKDLENSQNETINFK 1774

Query: 1439 QQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQK---ESEIERVKLIEELNVKI 1495
             +L   +K IEDL  +KE     L L+   +    +T+Q    E+  + VK I+ELN K 
Sbjct: 1775 NELNYTKKLIEDLKQQKEDIQNELDLEKQHSEEISKTLQSKIDENTSQNVK-IQELNEKT 1833

Query: 1496 ----TESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTL---NDE----ITNLQ 1544
                 ES S   +V ELN  ++ + A   +M+  L +Q++E  T+   N++    I +L 
Sbjct: 1834 ISLQKESDSYKLKVDELNSDIKRKNAMIEDMKNHLISQKVENETIYKSNNQMKAKIESLY 1893

Query: 1545 NMVRASSSKIQKH 1557
            N ++ + +KI ++
Sbjct: 1894 NEIKENKAKIDEY 1906



 Score =  151 bits (366), Expect = 2e-34
 Identities = 238/1220 (19%), Positives = 530/1220 (43%), Gaps = 99/1220 (8%)

Query: 415  QSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTED 474
            Q  N+ +   +  IS  +              + + +L+ + Q+  E    I +  NTE 
Sbjct: 1285 QQTNEVISQAKAKISRLERKLTESNSSNKDLQSKVDELKKKLQESSENE--IKIKQNTEQ 1342

Query: 475  VN-EIAK---VQEQLKQELND-EIKDVN----VKDLIEKLKSAEEQITQLN---DEIDAA 522
            +  E+ K    QEQLK++L + +  ++N    + DL   LK +E+Q T+L    DE   +
Sbjct: 1343 MRIEMEKRITEQEQLKKQLTELQTNNINNQKQINDLNNTLKISEKQRTELQVKFDEQTKS 1402

Query: 523  NKNMIKVK-------SNHKLKLK---QMQKTIDNF--SKVSDSNKEIVRLTEELHHLSQK 570
            NK ++  K       +N   K+K   + Q  ++N   ++ S  N +IV+   E+  L++K
Sbjct: 1403 NKEIVDQKQQQIYSLNNEISKMKADIEKQNALNNDLNTEKSSLNVKIVKFESEIKSLNEK 1462

Query: 571  VAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQEL 630
            +  ++E   N QL        + +E ++  ++ E+ NL E   K ++    ++  + +E 
Sbjct: 1463 LTNMKEIIANSQLEK------KKLEEEIKSRVKELSNLQEENAKLLTSSHEKEITMQKEK 1516

Query: 631  --HILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLD 688
              +  Q+   E+E+K A+IS+L+  +  S+ +  H     + LS  +K+ + + + L++ 
Sbjct: 1517 FENETQKMKKEIEEKTANISELE--KALSDKERNHK----NLLSKIQKKYSQLEDKLEIA 1570

Query: 689  KEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQ 748
            +E+L  + K +++ K  I    QN +Q   +    +  M+ +   E   K N   Q K  
Sbjct: 1571 EEKLEESDKKVKDLKNIITLHKQNQVQMENEHNQLINDMNKQHDQE---KNNLSLQLK-S 1626

Query: 749  TQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQE 808
             +  I+  IQE++ Y   I +      S    LE++ A ++ +   +E+   Q+ S ++ 
Sbjct: 1627 LENQIENLIQEKESYETEISTVYGDRDSMKQALEKASAFIQKKSIKIEKMKKQM-SQVKV 1685

Query: 809  KQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQIS 868
              ++ +E   +++  +  L  L +    + KQ ++I   N  + K N  + E++Q L   
Sbjct: 1686 TIESMNEELSEKENQIEELQKLTNR---LGKQKVQITETNDAISKLNAEIAEKDQKL-FE 1741

Query: 869  LSDMQQHYNALVEKANRT--DL--AESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKE 924
            +  +++  + L E   +   DL  +++E+  ++ +L   +  ++ +  + + +  +   E
Sbjct: 1742 MEVLKKKISQLTETIEKLTKDLENSQNETINFKNELNYTKKLIEDLKQQKEDIQNELDLE 1801

Query: 925  IEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKM 984
             +  E E +  ++S I +    N K ++  E    L+ +   YK  ++ LN +++  N M
Sbjct: 1802 KQHSE-EISKTLQSKIDENTSQNVKIQELNEKTISLQKESDSYKLKVDELNSDIKRKNAM 1860

Query: 985  NLELIDKHVQKQQTQSPDYTEQYINEINKLNALL------KQKDEEIIALNQKINNAQVS 1038
             +E +  H+  Q+ ++    +       K+ +L       K K +E    + K++  +  
Sbjct: 1861 -IEDMKNHLISQKVENETIYKSNNQMKAKIESLYNEIKENKAKIDEYQRESAKVDVERTQ 1919

Query: 1039 YMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKET 1098
            +   + DYE K+          EE++    K+    K+  E+     +E D+Q+  L ++
Sbjct: 1920 FQLTIKDYEMKVKDENNLRLTTEEKLSNAQKENDLLKKEIEK-----KENDNQL--LSQS 1972

Query: 1099 KLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEE-EEFIQERSVL 1157
            K +    + + + ++     +  S +    D             K + E E+  + +S L
Sbjct: 1973 KDSSLQTVTQLKSLVEEKEKQIASLNKKVADYESTIHESEIYQTKTKLEIEDITKSKSTL 2032

Query: 1158 QEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTV 1217
            Q+    ++ +      +I+  ++  + LT      QE   +LK    Q NT+ ++L + +
Sbjct: 2033 QQLLDTISNDKSNLEKQILDQKSTVSLLTAQISNLQESEQKLKLTQIQNNTQINDLNNKI 2092

Query: 1218 AELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQS 1277
            +E+  +     DQ   EI +  +  + + E       +EL       E+   Q    +Q 
Sbjct: 2093 SEMTKT-----DQTKSEIIQNHQNKIHELELQLLDKNNELNNANKEIENIKSQTESIIQK 2147

Query: 1278 STQEETNKIVTMEQV-TSLQN-KLQDKEEH--LRNLQEKYADVINQIEILRSEIEDEKVA 1333
            +  E  NK   +    T  +N K Q+ +    + ++ +  +D+   + +L +++ D K+ 
Sbjct: 2148 TAFEIQNKTEILNNYETKFENMKKQNAKAAVTINDMTKSSSDLRKHVNLLENQLFDSKMK 2207

Query: 1334 FXXXXXXXXXXXXXXXXDLRTENQS--YKQMQEQSILNINEENAQLKKSSXXXXXXXXXX 1391
                               +  N+S  +    +  +   +++   L++            
Sbjct: 2208 IENLTKELNESQNKIQSMTKQINESRAFSSTLQTKLDRESKQKESLQRELNFTQTELTKI 2267

Query: 1392 XXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDL 1451
                ++ ++K+L   H  E++ +      + Y++   +   E EN R+ L   E+ I D+
Sbjct: 2268 QTEASEYKSKIL---HTSEMESA----MQNSYSLIEEKLKSE-ENKRRNL---ERLITDM 2316

Query: 1452 TYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKA 1511
               ++   +  + ++     + + ++ E++    KLI E+     ++V L +++++L+  
Sbjct: 2317 RLTRDVNSSPKKQEIESLKINLQNLENEND----KLINEIKTLNEKNVLLQQEISKLSSD 2372

Query: 1512 LEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSF-ASDTKQGRDE 1570
            L+E+      +     +   EI  L ++I + +  +  S+S ++K +S  A   +Q +DE
Sbjct: 2373 LQEKEKSEKSLLQKQNDLISEISKLKNDIKDHKINLSQSTSSLKKDISTKAKQIEQSKDE 2432

Query: 1571 QLDN--TMNKELLDAVPRAE 1588
             L+N  T N  L   +   E
Sbjct: 2433 -LNNLQTENNSLKKKIQNLE 2451



 Score =  134 bits (325), Expect = 1e-29
 Identities = 203/998 (20%), Positives = 417/998 (41%), Gaps = 71/998 (7%)

Query: 144  VTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXX 203
            ++ L+  I EKD  L     +M++++  I  L E I +  + +E     T          
Sbjct: 1725 ISKLNAEIAEKDQKL----FEMEVLKKKISQLTETIEKLTKDLENSQNETINFKNELNYT 1780

Query: 204  XXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLK----DIESKDVRISSLEEANKL 259
                    ED KQQ   +Q N + +E +  +E  + L+    +  S++V+I  L E    
Sbjct: 1781 KKLI----EDLKQQKEDIQ-NELDLEKQHSEEISKTLQSKIDENTSQNVKIQELNEKTIS 1835

Query: 260  LEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIA 319
            L+       L+  +L  ++++              L  Q +E     K+  + K  +E  
Sbjct: 1836 LQKESDSYKLKVDELNSDIKRKNAMIEDMKNH---LISQKVENETIYKSNNQMKAKIESL 1892

Query: 320  --NMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRN 377
               + E   KI+  +  + ++     + +  +     + K  ++        +S     N
Sbjct: 1893 YNEIKENKAKIDEYQRESAKVDVERTQFQLTIKDYEMKVKDENNLRLTTEEKLSNAQKEN 1952

Query: 378  TASKMKSPWSQLSSETLNQDTDKKIN-----KNEIAKLEMVIQSLNKDLVDKEYVISEKD 432
               K +    +  ++ L+Q  D  +      K+ + + E  I SLNK + D E  I E +
Sbjct: 1953 DLLKKEIEKKENDNQLLSQSKDSSLQTVTQLKSLVEEKEKQIASLNKKVADYESTIHESE 2012

Query: 433  TXXXXXXXX----XXGKDTLIAQLQL--EHQQHMEGPSLIHVGTNTEDVNEIAKVQE-QL 485
                            K TL   L      + ++E   L    T +    +I+ +QE + 
Sbjct: 2013 IYQTKTKLEIEDITKSKSTLQQLLDTISNDKSNLEKQILDQKSTVSLLTAQISNLQESEQ 2072

Query: 486  KQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTID 545
            K +L     +  + DL  K+ S   +  Q   EI   ++N I     H+L+L+ + K   
Sbjct: 2073 KLKLTQIQNNTQINDLNNKI-SEMTKTDQTKSEIIQNHQNKI-----HELELQLLDKN-- 2124

Query: 546  NFSKVSDSNKEIVRLTEELHHLSQKVA-ELEEEKGNLQLHLVDYDSGRMIESDVYKKMIE 604
              ++++++NKEI  +  +   + QK A E++ +   L  +   +++ +   +     + +
Sbjct: 2125 --NELNNANKEIENIKSQTESIIQKTAFEIQNKTEILNNYETKFENMKKQNAKAAVTIND 2182

Query: 605  MENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADIS-QLQSDQVCSEIKSVH 663
            M   +    K ++LLE+Q FD   ++  L ++ +E ++K+  ++ Q+   +  S      
Sbjct: 2183 MTKSSSDLRKHVNLLENQLFDSKMKIENLTKELNESQNKIQSMTKQINESRAFSSTLQTK 2242

Query: 664  LEEQIDALSASKKELALVIENL-KLDKEQLYGTIKDLE-NDKEDIMNKLQNYIQENMDLT 721
            L+ +     + ++EL      L K+  E      K L  ++ E  M    + I+E +   
Sbjct: 2243 LDRESKQKESLQRELNFTQTELTKIQTEASEYKSKILHTSEMESAMQNSYSLIEEKLKSE 2302

Query: 722  DKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRL 781
            +   +     I+++  ++  +  S  + Q     +I+   + ++N+E+E  K       L
Sbjct: 2303 ENKRRNLERLITDM--RLTRDVNSSPKKQ-----EIESLKINLQNLENENDK-------L 2348

Query: 782  EESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLM----DHDRVV 837
               I  + ++   L+++  +L S LQEK+K+      ++++L++ ++ L     DH   +
Sbjct: 2349 INEIKTLNEKNVLLQQEISKLSSDLQEKEKSEKSLLQKQNDLISEISKLKNDIKDHKINL 2408

Query: 838  EKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQ 897
             +    ++ +     K+ +   +E  NLQ   + +++    L      T+ + ++S + Q
Sbjct: 2409 SQSTSSLKKDISTKAKQIEQSKDELNNLQTENNSLKKKIQNLEAVLQDTEDSLAQSNQSQ 2468

Query: 898  TQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYV 957
             Q++     L     E+Q L+  K+KEIE L  E + + +   + K  L    E+     
Sbjct: 2469 RQIKASYDLLNNKFEENQVLLNSKQKEIERLTNEVSDKEKELEKTKSELINIQERIRSDS 2528

Query: 958  TQLEAQLQEYKNNIENLNMNVEELNKMNLELIDK-HVQKQQTQS-PDYTEQYINE-INKL 1014
            ++L   + E +  +E+LN+ +E++  +N EL  K +    Q QS  D  ++ IN  I++ 
Sbjct: 2529 SKLNQDINEKQTKLESLNIELEKMRNINRELTSKVNSLTSQLQSIADSNQKDINTYISQY 2588

Query: 1015 NALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDS 1074
            N   K   +E+   N+ +       +    +   K+    T +E ++ E+ R  + L+  
Sbjct: 2589 NE-EKSTRKELEKSNETLKKKLEEKVKENKNLSVKITSLKTNIEELQIEVTRTQRTLV-P 2646

Query: 1075 KQHNEELQILVREQ----DDQIKELKETKLTFEMNIPK 1108
            K   E LQ  V E     DD  + L E K  +   I K
Sbjct: 2647 KNQLESLQKSVNEMSRKLDDAQQNLAEQKSRYSSIIEK 2684



 Score =  126 bits (305), Expect = 4e-27
 Identities = 281/1526 (18%), Positives = 637/1526 (41%), Gaps = 147/1526 (9%)

Query: 168  METTILDLQEKINEKDQIIEA--KNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENF 225
            +E    DLQ++I++    +EA  +N   +                 +   QQ T+    +
Sbjct: 203  LEQKNADLQDEISQLQSKLEAASRNAVDSEEMQNQNSQVQQEILILKQKLQQQTETLNQY 262

Query: 226  IAMEAEWKDEKQRLLKDIESKDVR-ISSLEEANKLLEAARFEISLEHSKLAQELEQXXXX 284
            +      +++   L + ++      +++ ++  + L+  R  +  E++KL + + Q    
Sbjct: 263  VVDITNERNKNNELEQQLQELHFNGVANPQQYAQDLDELR-NVKSENTKLNERISQLQMI 321

Query: 285  XXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKE 344
                      L KQ I+   E+  ++ +       N+ E+++ I  L+  N  + +    
Sbjct: 322  NDENESKIQNLVKQ-IQEKDEKYGDVAQSLEERQNNLKEMSENIIKLQSENSALTKERNS 380

Query: 345  LENKLA--TMGT-ESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDK- 400
            L ++L   TM   E ++     ++ S  + R   ++T    +    Q     +N + ++ 
Sbjct: 381  LSSELQQKTMFIDELQSNLKQVEEKSRTVYRSGNKSTIVDDRVKTLQERFNAVNSEKEEL 440

Query: 401  KINKNEIAKL----EMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEH 456
            K+  +++ +L    +  I  L K+  + +  I+EK               T+I ++Q E+
Sbjct: 441  KLTLDQVKQLVTDQQRQILQLKKENSELKQNINEK-----TDEDDSFNLSTMINKMQKEN 495

Query: 457  QQHMEG--PSLIHVGTNTE--------DVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLK 506
             + ++    S+  +    +          N   + QE+ +  L + + +  +  L +   
Sbjct: 496  SEDIDKLHKSITELQNQVQYWKEKCLSQENSFKENQEKFRISLMENVTNQTILPLQQSNN 555

Query: 507  SAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEI---VRLTEE 563
              ++QI +L ++I        +V+S +K K +QM+K I    K    NK++   +   E+
Sbjct: 556  DKDQQIKELMNQIKLIKDKQDEVESKNKAKDQQMKKLIKELEKEQKKNKDLTLTIANAED 615

Query: 564  LHHL-SQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQ 622
              H+ +Q  A +++ +  +     +         ++ K+   ++N  E+    IS L+ +
Sbjct: 616  PKHIQTQMQARIDDLQSEISNLKQEIQQNEQKYQNLKKENKSLKNDNESANHTISALQ-E 674

Query: 623  KFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVI 682
            +   + +   L +K +E ++K  D  +  ++++ + I S   +++ + L    K L  +I
Sbjct: 675  EIKKISDNTDLTRKIEE-QEKEVDQLRKYNEKLETTISSSKQQKE-EMLHNQNKALKQMI 732

Query: 683  ENLKLDKEQLYGTIKDLE-NDKEDIMNKLQNYIQENMDL----TDKLEKMSAEKISELLA 737
               KL KE     +     N   D  N +     E M L    T++L+++ + K+  + +
Sbjct: 733  --FKLAKEISPNAVHSTSFNKMADEFNMMSQTFNETMKLKEAATNQLKRIDS-KVYGITS 789

Query: 738  KINHE---EQSKIQTQFG--IDAKIQERDLYIENIESELSKYKSRICRLEESIAVMED-- 790
            + N E   +  K  T+    ++ + Q     ++++ ++       I  L+     + D  
Sbjct: 790  RYNIETVDDTVKALTELDNLLNIEKQRTQKNLDDLANKTEDLMDEIDSLQSVNVSLTDQN 849

Query: 791  --------RRYSLERKADQLGSYLQEKQKAYSEYTI--QEDELVNRLAV----LMDHDRV 836
                    R   +ER  + L   L    +  ++Y +  Q  E   ++      L D  + 
Sbjct: 850  KKQQIEIIRLQGIERSVEGLNEDLNSAYQLINQYELANQNSEYAQQMKFIKKKLKDKQKQ 909

Query: 837  VEK------QLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAE 890
            ++K      +LL+++ EN  L+K+   L E  + +  +L    +   +L +   R    E
Sbjct: 910  IQKYKSSVNELLDVQSENNSLKKQISDLNENIREMNGALKAANKKLQSLDKLHQRKLEME 969

Query: 891  SESTKYQTQLRDLE---SNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVL- 946
             + +   T  R L+    +L++   E +    +K   +E    + N+QI+   + + ++ 
Sbjct: 970  DQISSLMTACRQLQMDKESLQKKVDELKKSNEEKDDALESYRDKLNSQIDILGQSQSIIE 1029

Query: 947  --NEKYEKNIEYVTQLEAQLQEYKNNIENL--NMN-VEELNKMNLELIDKHVQK--QQTQ 999
              N+K  K+   + +L+ +L      IE +   MN  E  NK N E + K  QK  + T+
Sbjct: 1030 NANDKSRKDSNAIQELKEKLINSDKEIEKMKKEMNDYENTNKSNKENLLKLQQKIIEVTR 1089

Query: 1000 SPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLEN 1059
            + + TE ++   + ++ LL   D  + A + K  +  ++ +  V D  +   +F +   N
Sbjct: 1090 TVNPTENHVRVSDNVSQLLNDLDLIVKAFSDK--DKTINEIKGVIDKNNN--EFISFKSN 1145

Query: 1060 MEEEMQRVSKQLLDSKQHNEELQI---LVREQDDQIKELK-------ETKLTFE--MNIP 1107
            +   +   S++L+    +N+ L +    V+ Q DQI E+K       +   T++  ++ P
Sbjct: 1146 LSNIISSFSQKLVSETDNNKLLNLTNDFVKSQVDQINEIKSQIVQIIKNSSTYKPTLSSP 1205

Query: 1108 KTEGM-IISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNT 1166
            + E + I+   I       N +             L + +  +  Q+ +  ++    L  
Sbjct: 1206 QNELLDILREIISEHEVTENKLGSEVTYLNDILNQLDI-KNSDLAQQIAEHRQGYEILKQ 1264

Query: 1167 ELQECYTKIIQLET--LNTELTGHDVVNQ--EQINQLKSKLEQLNTENDNLLSTVAELRS 1222
            +L E    I + E+     +   ++V++Q   +I++L+ KL + N+ N +L S V EL+ 
Sbjct: 1265 KLDEASHIIEEKESNVFEEKQQTNEVISQAKAKISRLERKLTESNSSNKDLQSKVDELKK 1324

Query: 1223 SISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEE 1282
             +                Q  ++ E   ++   ++R+++    ++ EQL   +   T+ +
Sbjct: 1325 KL----------------QESSENEIKIKQNTEQMRIEMEKRITEQEQLKKQL---TELQ 1365

Query: 1283 TNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAF---XXXXX 1339
            TN I   +Q+  L N L+  E+    LQ K+ +     + +  + + +  +         
Sbjct: 1366 TNNINNQKQINDLNNTLKISEKQRTELQVKFDEQTKSNKEIVDQKQQQIYSLNNEISKMK 1425

Query: 1340 XXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAE 1399
                       DL TE  S      +    I   N +L                   + +
Sbjct: 1426 ADIEKQNALNNDLNTEKSSLNVKIVKFESEIKSLNEKLTNMKEIIANSQLEKKKLEEEIK 1485

Query: 1400 AKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESEL 1459
            ++V EL++ L+ +++++   +HE  IT+  + ++FEN  Q++   +K IE+ T       
Sbjct: 1486 SRVKELSN-LQEENAKLLTSSHEKEITM--QKEKFENETQKM---KKEIEEKTANISELE 1539

Query: 1460 AILRLKMHENANHYETMQKE-SEIE-RVKLIEELNVKITESVSLNKQVAELNKALEEEVA 1517
              L  K   + N    +QK+ S++E ++++ EE   K+ ES   +K+V +L   +   + 
Sbjct: 1540 KALSDKERNHKNLLSKIQKKYSQLEDKLEIAEE---KLEES---DKKVKDLKNII--TLH 1591

Query: 1518 KTNEMQTALENQEIEIVT-LNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTM 1576
            K N++Q  +EN+  +++  +N +    +N +      ++  +      K+  + ++    
Sbjct: 1592 KQNQVQ--MENEHNQLINDMNKQHDQEKNNLSLQLKSLENQIENLIQEKESYETEISTVY 1649

Query: 1577 NKELLDAVPRAELDLAMYMLHQRDVR 1602
                 D++ +A L+ A   + ++ ++
Sbjct: 1650 GDR--DSMKQA-LEKASAFIQKKSIK 1672



 Score =  111 bits (267), Expect = 2e-22
 Identities = 184/936 (19%), Positives = 397/936 (42%), Gaps = 76/936 (8%)

Query: 660  KSVHLEEQIDALSASKKELALVIENLKLDKE----QLYGTIKDLEN---DKEDIMNKLQN 712
            KS+ LEE+  A     + L + +E    D +    QL   ++       D E++ N+   
Sbjct: 181  KSILLEERRQASERFGRSLFIELEQKNADLQDEISQLQSKLEAASRNAVDSEEMQNQNSQ 240

Query: 713  YIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAK----IQERDLYIENIE 768
              QE + L  KL++ + E +++ +  I +E     + +  +       +     Y ++++
Sbjct: 241  VQQEILILKQKLQQQT-ETLNQYVVDITNERNKNNELEQQLQELHFNGVANPQQYAQDLD 299

Query: 769  SELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLA 828
             EL   KS   +L E I+ ++      E K   L   +QEK + Y +     +E  N L 
Sbjct: 300  -ELRNVKSENTKLNERISQLQMINDENESKIQNLVKQIQEKDEKYGDVAQSLEERQNNL- 357

Query: 829  VLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDL 888
                  + + + +++++ EN  L K+   L  E Q   + + ++Q +   + EK+     
Sbjct: 358  ------KEMSENIIKLQSENSALTKERNSLSSELQQKTMFIDELQSNLKQVEEKSRTVYR 411

Query: 889  AESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNE 948
            + ++ST    +++ L+     +  E + L    K  ++ ++ +  T  +  I   K  N 
Sbjct: 412  SGNKSTIVDDRVKTLQERFNAVNSEKEEL----KLTLDQVK-QLVTDQQRQILQLKKENS 466

Query: 949  KYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYI 1008
            + ++NI   T         +++  NL+  + ++ K N E IDK + K  T+  +   QY 
Sbjct: 467  ELKQNINEKTD--------EDDSFNLSTMINKMQKENSEDIDK-LHKSITELQNQV-QYW 516

Query: 1009 NE--INKLNALLKQKDEEIIALNQKINNAQVSYMSMV-SDYESKLAQFTTKLENMEEEMQ 1065
             E  +++ N+  + +++  I+L + + N  +  +    +D + ++ +   +++ ++++  
Sbjct: 517  KEKCLSQENSFKENQEKFRISLMENVTNQTILPLQQSNNDKDQQIKELMNQIKLIKDKQD 576

Query: 1066 RVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTF-EMNIPKTEGMIISSTIEPMSDD 1124
             V  +   +K  +++++ L++E + + K+ K+  LT      PK     + + I+ +  +
Sbjct: 577  EVESK---NKAKDQQMKKLIKELEKEQKKNKDLTLTIANAEDPKHIQTQMQARIDDLQSE 633

Query: 1125 ANNVDXXXXXXXXXXXXLKVQ------EEEEFIQERSVLQEQSAKL--NTELQECYTKII 1176
             +N+             LK +      + E      S LQE+  K+  NT+L     KI 
Sbjct: 634  ISNLKQEIQQNEQKYQNLKKENKSLKNDNESANHTISALQEEIKKISDNTDLTR---KIE 690

Query: 1177 QLETLNTELTGHDVVNQEQINQLK-SKLEQLNTENDNLLSTVAELRSSIS-SAVDQRGF- 1233
            + E    +L  ++   +  I+  K  K E L+ +N  L   + +L   IS +AV    F 
Sbjct: 691  EQEKEVDQLRKYNEKLETTISSSKQQKEEMLHNQNKALKQMIFKLAKEISPNAVHSTSFN 750

Query: 1234 EIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVT 1293
            ++A+ +   ++Q   +  K +     QL   +SK   +       T ++T K +T E   
Sbjct: 751  KMADEFNM-MSQTFNETMKLKEAATNQLKRIDSKVYGITSRYNIETVDDTVKALT-ELDN 808

Query: 1294 SLQNKLQDKEEHLRNLQEKYADVINQIEILRS---EIEDEKVAFXXXXXXXXXXXXXXXX 1350
             L  + Q  +++L +L  K  D++++I+ L+S    + D+                    
Sbjct: 809  LLNIEKQRTQKNLDDLANKTEDLMDEIDSLQSVNVSLTDQNKKQQIEIIRLQGIERSVEG 868

Query: 1351 DLRTENQSYKQMQEQSILNINEENAQ----LKKSSXXXXXXXXXXXXRVNDAEAKVLELT 1406
                 N +Y+ + +  + N N E AQ    +KK               VN+    V    
Sbjct: 869  LNEDLNSAYQLINQYELANQNSEYAQQMKFIKKKLKDKQKQIQKYKSSVNEL-LDVQSEN 927

Query: 1407 HQLELKDSEIYQKTHEYTITLTQRNDEFEN---VRQQLVEYEKRIEDL---TYEKESELA 1460
            + L+ + S++ +   E    L   N + ++   + Q+ +E E +I  L     + + +  
Sbjct: 928  NSLKKQISDLNENIREMNGALKAANKKLQSLDKLHQRKLEMEDQISSLMTACRQLQMDKE 987

Query: 1461 ILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTN 1520
             L+ K+ E     E      E  R KL  ++++ + +S S+   +   N    ++     
Sbjct: 988  SLQKKVDELKKSNEEKDDALESYRDKLNSQIDI-LGQSQSI---IENANDKSRKDSNAIQ 1043

Query: 1521 EMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQK 1556
            E++  L N + EI  +  E+ + +N  +++   + K
Sbjct: 1044 ELKEKLINSDKEIEKMKKEMNDYENTNKSNKENLLK 1079



 Score = 92.7 bits (220), Expect = 8e-17
 Identities = 176/923 (19%), Positives = 382/923 (41%), Gaps = 73/923 (7%)

Query: 141  LGDVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIE--AKNKATTXXXX 198
            L  VT L + ++EK+  ++ L  K+   E+TI + +    +    IE   K+K+T     
Sbjct: 1977 LQTVTQLKSLVEEKEKQIASLNKKVADYESTIHESEIYQTKTKLEIEDITKSKSTLQQLL 2036

Query: 199  XXXXXXXXXXXXXE-DTKQQMTKMQENFIAM-EAEWKDEKQRLLKDIESKDVRISSLEEA 256
                           D K  ++ +      + E+E K +  ++  + +  D+  + + E 
Sbjct: 2037 DTISNDKSNLEKQILDQKSTVSLLTAQISNLQESEQKLKLTQIQNNTQINDLN-NKISEM 2095

Query: 257  NKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSL 316
             K  +  + EI   H     ELE                A + IE    +   I +K + 
Sbjct: 2096 TKT-DQTKSEIIQNHQNKIHELELQLLDKNNELNN----ANKEIENIKSQTESIIQKTAF 2150

Query: 317  EIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGR 376
            EI N TE+      L +   +     K+      T+   +K+ SS  +K   L+  +   
Sbjct: 2151 EIQNKTEI------LNNYETKFENMKKQNAKAAVTINDMTKS-SSDLRKHVNLLENQLF- 2202

Query: 377  NTASKMKSPWSQLS-SETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXX 435
            ++  K+++   +L+ S+   Q   K+IN++  A    +   L+++   KE +  +++   
Sbjct: 2203 DSKMKIENLTKELNESQNKIQSMTKQINESR-AFSSTLQTKLDRESKQKESL--QRELNF 2259

Query: 436  XXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDE--I 493
                      +    + ++ H   ME           E +      +  L++ + D    
Sbjct: 2260 TQTELTKIQTEASEYKSKILHTSEMESAMQNSYSLIEEKLKSEENKRRNLERLITDMRLT 2319

Query: 494  KDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDS 553
            +DVN     ++++S +  +  L +E D     +  +   + L  +++ K   +  +   S
Sbjct: 2320 RDVNSSPKKQEIESLKINLQNLENENDKLINEIKTLNEKNVLLQQEISKLSSDLQEKEKS 2379

Query: 554  NKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYD-SGRMIESDVYKKMIEMENLAETR 612
             K +++   +L      ++E+ + K +++ H ++   S   ++ D+  K  ++E   +  
Sbjct: 2380 EKSLLQKQNDL------ISEISKLKNDIKDHKINLSQSTSSLKKDISTKAKQIEQSKDE- 2432

Query: 613  LKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCS-EIKSVHLEEQIDAL 671
               ++ L+++   L +++  L+    + ED LA  +Q Q     S ++ +   EE    L
Sbjct: 2433 ---LNNLQTENNSLKKKIQNLEAVLQDTEDSLAQSNQSQRQIKASYDLLNNKFEENQVLL 2489

Query: 672  SASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEK 731
            ++ +KE+  +   +   +++L  T  +L N +E I +      Q+  +   KLE ++ E 
Sbjct: 2490 NSKQKEIERLTNEVSDKEKELEKTKSELINIQERIRSDSSKLNQDINEKQTKLESLNIEL 2549

Query: 732  ISELLAKINHEEQSKIQTQFGIDAKIQE-RDLYIENIESELSKYKSRICRLEESIAVMED 790
              E +  IN E  SK+ +   + +++Q   D   ++I + +S+Y       EE     + 
Sbjct: 2550 --EKMRNINRELTSKVNS---LTSQLQSIADSNQKDINTYISQYN------EE-----KS 2593

Query: 791  RRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKE 850
             R  LE+  + L   L+EK K     +++   L   +  L       ++ L+  +++ + 
Sbjct: 2594 TRKELEKSNETLKKKLEEKVKENKNLSVKITSLKTNIEELQIEVTRTQRTLVP-KNQLES 2652

Query: 851  LQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTD-----LAESESTKYQTQLRDLES 905
            LQK    +  +  + Q +L++ +  Y++++EK N        L ES  + +       +S
Sbjct: 2653 LQKSVNEMSRKLDDAQQNLAEQKSRYSSIIEKYNEKTSLLSLLTESFISVHSLIANQSKS 2712

Query: 906  NLKRITHEHQTL----IVQKKKEIEDLEIEFN--TQIESAIRDKKVLNEKYEKNIEYVTQ 959
            NL +     Q L     + K   +   +I F    +++ ++    + + K   N   +T+
Sbjct: 2713 NLSQKQFLMQILEKMSAIFKAMNLSMPQISFAQLNRLDVSVSSVDIFDIKMTHNFRLLTE 2772

Query: 960  LEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLK 1019
             + +L      I  + +N+ +L     E +      QQ       E   N ++++ +++ 
Sbjct: 2773 EDEKL------INAIKLNLSDLAVSTSERLPSFTASQQLSGK--LEYIRNLVSRVKSVID 2824

Query: 1020 QKDEEIIALNQKINNAQVSYMSM 1042
            QKD EI  LNQ+I     + M +
Sbjct: 2825 QKDSEIDRLNQQIAKQHETVMKI 2847


>UniRef50_Q22AT3 Cluster: Viral A-type inclusion protein repeat
            containing protein; n=1; Tetrahymena thermophila
            SB210|Rep: Viral A-type inclusion protein repeat
            containing protein - Tetrahymena thermophila SB210
          Length = 3812

 Score =  186 bits (452), Expect = 6e-45
 Identities = 225/1129 (19%), Positives = 510/1129 (45%), Gaps = 104/1129 (9%)

Query: 233  KDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXX 292
            K+E +  +  IE   V I  L+ A+KL +  + +I  +  + ++++              
Sbjct: 2699 KEELKLKIISIEEMSVVIDDLK-ASKLQQDNQIQIIQQQLQESEQINSQLHSQVENYQEN 2757

Query: 293  XXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELE---NKL 349
                + ++E   +EK EI  +     +  TE   ++E+ + L  QI + N+  +   N+L
Sbjct: 2758 IKQIQDTLEQLKQEKQEITNQ-----SEQTEKDLQLEIQKLLQ-QIEEQNQNFQVQINEL 2811

Query: 350  ATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAK 409
            + +G  +K V    ++      +K+ ++   ++K+  S  + +T+ Q    KI       
Sbjct: 2812 SNLGANNKLVIQEKQE-----LQKNIQDLKDQLKTTQSN-NKQTI-QSLQAKIE------ 2858

Query: 410  LEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVG 469
             E+  Q   ++ ++ +  +  ++            K+  + +   E  + +E   L  V 
Sbjct: 2859 -ELTTQICQQNELNNQ--LKSQNQQNIHQIEELNIKNNFLNKTLKEQVEQLE-QELNSVQ 2914

Query: 470  TNTEDVNEIAKVQEQLKQELNDEIKDVN--VKDLIEKLKSAEEQITQLNDEIDAANKNMI 527
               E+ N+I+K Q+   + L +    +N  ++DL    ++ E QI QL ++++   K  +
Sbjct: 2915 EKLEEKNKISKEQQNQFEALQENCVQLNQKIQDLQLNKQNQEHQIQQLQNQLNVFEKENL 2974

Query: 528  KVKSNHKLKLKQMQKTIDNFSKV-SDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLV 586
              K     K K+     +    + S  N E    +++L    Q++  +  EK  ++  L 
Sbjct: 2975 LQKEQISAKTKEANGLREELDVINSQKNLEQTESSKQLQEFCQQMETITREKNQIKQELE 3034

Query: 587  DY--DSGRMIESD---VYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVE 641
             +  DS    +S+   + +   E+  + +   K   +LE    +   E   LQQ+  +V 
Sbjct: 3035 QFQLDSSNQSKSERQQINQLESELAQIKQREQKQKVILEENSKNHKIEKEELQQQIKQVN 3094

Query: 642  DKLADISQ--LQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDL 699
              L    +  +Q ++  +++   H  EQI+ LS  +K L      L L  +++ G I  +
Sbjct: 3095 SVLKAEQENFIQKEKSLNQVIKGH-SEQIEQLSNEQKALQ---NQLNLKNQEIAGLILQM 3150

Query: 700  ENDKEDIMNKLQNYIQENMDLTDKLEK-----MSAEKISELLAKINHEEQSKIQTQFGID 754
            +N +E      Q  +Q N D+++  E+      + EK+ E L ++N+    K+     ++
Sbjct: 3151 KNKEEQQQQLSQKIVQLNQDISNITEQSNIKIQNGEKLIEELQELNNSNHEKLND---LE 3207

Query: 755  AKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYS 814
            +K++ +    + I+S  S+Y+  I +L++++    +    LE++  +    +++K K   
Sbjct: 3208 SKLKAQQ---QTIKSSASEYQKNIKQLQDNLQKQTNVNSELEKQNQENLKLIKQKDKQLE 3264

Query: 815  EYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQ 874
            E   Q++++ ++     +  +++ K+  + + E K+L  K +   ++ Q ++  L ++++
Sbjct: 3265 EINTQKEKMSSQYQEEKEQSQIINKKYQQQDQELKQLLVKLENYEKQEQEIKNKLINVEE 3324

Query: 875  HYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNT 934
              + L++  N  ++          ++ +LE ++KRI  EH     + + +  +L ++ NT
Sbjct: 3325 EKSKLIDSQNILEV----------KVLNLEEHIKRIQEEHSCKTKEFENKQNEL-LQSNT 3373

Query: 935  QIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQ 994
             +     + + + +++E     +  L   L++ K   E+   N+EE+ K   +LI ++ Q
Sbjct: 3374 LLSKQSANLEDVYKQFELKQNDLLNLIQLLEKEKQEKESAIQNLEEIKK---QLISQNKQ 3430

Query: 995  KQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFT 1054
             Q+            ++N+  A LK +    + LN++++N+++    M+S+ ++K+ Q T
Sbjct: 3431 NQE------------KLNQAEADLKNQ----VQLNKELDNSKIQLEKMLSELQNKIEQNT 3474

Query: 1055 TKLENMEEEMQRV-------SKQLLDSKQHNEELQILVREQDDQIKEL--KETKLTFEMN 1105
                +M+++++++       +KQ+   K   +EL+  +  Q  +I EL  K  +++ E+N
Sbjct: 3475 QNANSMKDQLKKLQIQVDDQNKQINSEKAKADELKSTIENQVQKISELQNKNNQISKELN 3534

Query: 1106 IPKTEGMIISSTI--EPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQ-ERSVLQEQSA 1162
              K     +      + +  +    +             ++QE+ + +Q E + L++Q+ 
Sbjct: 3535 QEKASAQDLKEQFNNQKLVLEQQQKENINTSNNFKETNKQLQEQVKLLQSEINQLKQQND 3594

Query: 1163 KLNTELQ-ECYTKIIQLETLNTEL---TGHDVVNQEQINQLKSKLEQLNTENDNLLSTVA 1218
            KLN + Q E  T++  LE L +++   T      QEQI QL  K  Q     D LL    
Sbjct: 3595 KLNDKHQKELLTQVSILEELQSKIKSQTEQSSNYQEQIKQLSDKNIQNEQVIDQLLCKSK 3654

Query: 1219 ELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSS 1278
            +L +      ++   ++   +++ + Q E    +  + L  Q    +S + +L +     
Sbjct: 3655 DLETKFILEQEENQ-KLVNDYEEKMNQLELAKSEEVNSLIEQFKQEKSLWNELKNEENGK 3713

Query: 1279 TQEETNKIVT-----MEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEI 1322
             + E N++ T      EQV  LQ  + DKE  +  +++ + + ++QI++
Sbjct: 3714 IESERNELKTKMFELFEQVKVLQMVVSDKESEINTIKQSHKEELDQIQL 3762



 Score =  175 bits (427), Expect = 6e-42
 Identities = 300/1500 (20%), Positives = 628/1500 (41%), Gaps = 142/1500 (9%)

Query: 150  TIKEKDNALSVLQVKM---KIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXX 206
            TIK+K+  +  L+V++     ++  I  LQ+ + EK QII+   K               
Sbjct: 2032 TIKQKEQIILNLRVQVDDISNLQEQISQLQDALQEKQQIIDQIEKENIQQIYEETLIQKN 2091

Query: 207  XXXXXEDT----KQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEA 262
                  +     KQ++ K  EN I  E + K  +   L+ + + +++ + LE+ N  +++
Sbjct: 2092 ELLSINNKLNQEKQELQKAIEN-INQEIQQKSNQIDHLQTLNN-EIK-TELEQKNGKIKS 2148

Query: 263  ARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMT 322
               +I+ E+ +  Q L                  K        + T + E    ++ N  
Sbjct: 2149 QEDQIA-ENIQNIQVLNTENNQLKEEFSLKLNAYKSENIEQINQLTAVFENEKTQLENAI 2207

Query: 323  ELTKKIELLEHLNCQIRQTNKEL-ENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASK 381
            +  K+I   ++L  Q+   N+ + + +      +S+++    ++ + L+ ++  +    +
Sbjct: 2208 KQQKEIN--QNLENQVVNQNQNIIKMQQENQLIQSESIEKQKREFTELLKQQDEKLLNLR 2265

Query: 382  MKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXX 441
             +   S+  ++ L +  ++K N+N I +L+  IQSL + L   + +I+E           
Sbjct: 2266 NQFEDSKEENQLLREQNEQK-NQN-IQQLQQEIQSLQQQL---DNLINETSILRTENSEQ 2320

Query: 442  XXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVK-D 500
                     +  L+ +Q +E  + +   T+  D   + K QE+L+ +L   +    +  +
Sbjct: 2321 IQNLKKEREEFLLKMEQLVEAINKLKK-TSANDKQIMQKEQEELQSKLALVVSQAQINVN 2379

Query: 501  LIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRL 560
             I++L+  ++Q   L D++    K    +    K+   Q  + +     + +  K  +  
Sbjct: 2380 TIDELRQTKQQ---LEDQVLLLTKQADSLTLQSKMSESQFTEEMKKQILIFEQEK--INF 2434

Query: 561  TEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIES-DVYKKMIEMENL-----AETRLK 614
             + +  L QK+AE E +  N Q+ L+  +  +++     YK M + E        ++  +
Sbjct: 2435 EKTISQLEQKLAENELDSSN-QIQLLQEEQQKIVNQLQEYKNMYQTERQQNELNTQSLQQ 2493

Query: 615  AISLLESQKF----------DLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIK---- 660
               + E QK           D+V++    + +Y+E+  +   + QL  +Q    IK    
Sbjct: 2494 QFEICERQKLQIEEIQQRLEDIVEQNKETKNEYNELSVQKMSLEQLFEEQRGEFIKESDR 2553

Query: 661  SVHLEEQIDALSASKKELALVIENLKLDKEQLYGT-IKDLENDKEDIMNKLQNYIQENMD 719
            +  LE  I  L +  K L   ++NL    +Q Y   I ++EN++    NK   Y  EN  
Sbjct: 2554 NQKLENAIKNLESENKSLKDKLDNL----DQNYSNQILEIENER----NKCLQYEHENQS 2605

Query: 720  LTDKLEKMSAEKISEL----LAKINHEEQSKIQTQFGIDAKIQERDLYIENI---ESELS 772
            L +K       KI+EL     + I   E+ KIQ +    + +Q   L I+ +     +L 
Sbjct: 2606 LQEKCFSYQ-NKITELDETKKSLIRQLEEFKIQIK-DEQSTVQTLKLEIQKLIKQNEDLQ 2663

Query: 773  KYKSRIC--RLEESIAVMEDRRYSLERKA---DQLGSYLQEKQKAYSEYTIQEDELVNRL 827
            K    I   ++   + ++E + + L++ A   +Q+   L+ K  +  E ++  D+L    
Sbjct: 2664 KENQDIIENQVNAQLDILEKQNFDLQQLAQFNNQIKEELKLKIISIEEMSVVIDDLKASK 2723

Query: 828  AVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTD 887
                +  +++++QL E E  N +L  + +   E  + +Q +L  ++Q    +  ++ +T+
Sbjct: 2724 LQQDNQIQIIQQQLQESEQINSQLHSQVENYQENIKQIQDTLEQLKQEKQEITNQSEQTE 2783

Query: 888  L-AESESTKYQTQLRDLESNLKRITHE------HQTLIVQKKKEIEDLEIEFNTQIESAI 940
               + E  K   Q+ +   N +   +E      +  L++Q+K+E++    +   Q+++  
Sbjct: 2784 KDLQLEIQKLLQQIEEQNQNFQVQINELSNLGANNKLVIQEKQELQKNIQDLKDQLKTTQ 2843

Query: 941  RDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNM-NVEELNKMNLE--LIDKHVQKQQ 997
             + K   +  +  IE +T    Q  E  N +++ N  N+ ++ ++N++   ++K +++Q 
Sbjct: 2844 SNNKQTIQSLQAKIEELTTQICQQNELNNQLKSQNQQNIHQIEELNIKNNFLNKTLKEQV 2903

Query: 998  TQSPDYTEQYINEINKLNALLKQKD-------EEIIALNQKINNAQVSYMSMVSDYESKL 1050
             Q          ++ + N + K++        E  + LNQKI + Q++  +     E ++
Sbjct: 2904 EQLEQELNSVQEKLEEKNKISKEQQNQFEALQENCVQLNQKIQDLQLNKQNQ----EHQI 2959

Query: 1051 AQFTTKLENMEEE----MQRVSKQLLDSKQHNEELQILVR----EQDDQIKELKE----- 1097
             Q   +L   E+E     +++S +  ++    EEL ++      EQ +  K+L+E     
Sbjct: 2960 QQLQNQLNVFEKENLLQKEQISAKTKEANGLREELDVINSQKNLEQTESSKQLQEFCQQM 3019

Query: 1098 TKLTFEMNIPKTE--GMIISSTIEPMSD--DANNVDXXXXXXXXXXXXLKVQEEEEFIQ- 1152
              +T E N  K E     + S+ +  S+    N ++             KV  EE     
Sbjct: 3020 ETITREKNQIKQELEQFQLDSSNQSKSERQQINQLESELAQIKQREQKQKVILEENSKNH 3079

Query: 1153 --ERSVLQEQSAKLNTELQECYTKIIQLE-TLNTELTGHDVVNQEQINQLKSKLEQLNTE 1209
              E+  LQ+Q  ++N+ L+      IQ E +LN  + GH    ++  N+ K+   QLN +
Sbjct: 3080 KIEKEELQQQIKQVNSVLKAEQENFIQKEKSLNQVIKGHSEQIEQLSNEQKALQNQLNLK 3139

Query: 1210 NDNLLSTVAELRSS------ISSAVDQRGFEIAELWKQHLAQRE------ADFQKTEHEL 1257
            N  +   + ++++       +S  + Q   +I+ + +Q   + +       + Q+  +  
Sbjct: 3140 NQEIAGLILQMKNKEEQQQQLSQKIVQLNQDISNITEQSNIKIQNGEKLIEELQELNNSN 3199

Query: 1258 RVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVI 1317
              +L+  ESK +    +++SS  E    I  ++   +LQ +     E  +  QE    +I
Sbjct: 3200 HEKLNDLESKLKAQQQTIKSSASEYQKNIKQLQD--NLQKQTNVNSELEKQNQENLK-LI 3256

Query: 1318 NQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQL 1377
             Q +    EI  +K                     + ++Q  KQ+  + + N  ++  ++
Sbjct: 3257 KQKDKQLEEINTQKEKMSSQYQEEKEQSQIINKKYQQQDQELKQLLVK-LENYEKQEQEI 3315

Query: 1378 KKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENV 1437
            K                 N  E KVL L   ++    E   KT E           FEN 
Sbjct: 3316 KNKLINVEEEKSKLIDSQNILEVKVLNLEEHIKRIQEEHSCKTKE-----------FENK 3364

Query: 1438 RQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITE 1497
            + +L++    +   +   E       LK ++  N  + ++KE + E+   I+ L     +
Sbjct: 3365 QNELLQSNTLLSKQSANLEDVYKQFELKQNDLLNLIQLLEKEKQ-EKESAIQNLEEIKKQ 3423

Query: 1498 SVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNL--QNMVRASSSKIQ 1555
             +S NKQ  E     E ++    ++   L+N +I++  +  E+ N   QN   A+S K Q
Sbjct: 3424 LISQNKQNQEKLNQAEADLKNQVQLNKELDNSKIQLEKMLSELQNKIEQNTQNANSMKDQ 3483



 Score =  166 bits (403), Expect = 5e-39
 Identities = 305/1536 (19%), Positives = 659/1536 (42%), Gaps = 150/1536 (9%)

Query: 145  THLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINE--KDQIIEAKNKATTXXXXXXXX 202
            T L N IK++      L+ ++      I+ +Q++ N+  + + IE + +  T        
Sbjct: 2201 TQLENAIKQQKEINQNLENQVVNQNQNIIKMQQE-NQLIQSESIEKQKREFTELLKQQDE 2259

Query: 203  XXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEK-QRLLKDIESKDVRISSLEEANKLLE 261
                     ED+K++   ++E     + E K++  Q+L ++I+S   ++ +L     +L 
Sbjct: 2260 KLLNLRNQFEDSKEENQLLRE-----QNEQKNQNIQQLQQEIQSLQQQLDNLINETSIL- 2313

Query: 262  AARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANM 321
              R E S +   L +E E+              L K S       + E EE  S     +
Sbjct: 2314 --RTENSEQIQNLKKEREEFLLKMEQLVEAINKLKKTSANDKQIMQKEQEELQSKLALVV 2371

Query: 322  TELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASK 381
            ++    +  ++ L    RQT ++LE+++  +  ++ +++  SK      + +  +     
Sbjct: 2372 SQAQINVNTIDEL----RQTKQQLEDQVLLLTKQADSLTLQSKMSESQFTEEMKKQI--- 2424

Query: 382  MKSPWSQLSSETLNQDTDKKINKNEIAKLEMV--IQSLNKDLVDKEYVISEKDTXXXXXX 439
            +     +++ E      ++K+ +NE+     +  +Q   + +V++  +   K+       
Sbjct: 2425 LIFEQEKINFEKTISQLEQKLAENELDSSNQIQLLQEEQQKIVNQ--LQEYKNMYQTERQ 2482

Query: 440  XXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELND-EIKDVNV 498
                   +L  Q ++  +Q ++   +  +    ED+ E  K   + K E N+  ++ +++
Sbjct: 2483 QNELNTQSLQQQFEICERQKLQ---IEEIQQRLEDIVEQNK---ETKNEYNELSVQKMSL 2536

Query: 499  KDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDN--FSKVSDSNK- 555
            + L E+ +    + +  N +++ A KN+     + K KL  + +   N      ++ NK 
Sbjct: 2537 EQLFEEQRGEFIKESDRNQKLENAIKNLESENKSLKDKLDNLDQNYSNQILEIENERNKC 2596

Query: 556  -----EIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIE-SDVYKKMIEMENLA 609
                 E   L E+      K+ EL+E K +L   L ++      E S V    +E++ L 
Sbjct: 2597 LQYEHENQSLQEKCFSYQNKITELDETKKSLIRQLEEFKIQIKDEQSTVQTLKLEIQKL- 2655

Query: 610  ETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQID 669
               +K    L+ +  D+++    +  + D +E +  D+ QL   Q  ++IK     E++ 
Sbjct: 2656 ---IKQNEDLQKENQDIIENQ--VNAQLDILEKQNFDLQQLA--QFNNQIK-----EELK 2703

Query: 670  ALSASKKELALVIENLKLDKEQLYGTIKDLEN---DKEDIMNKLQNYI---QENM-DLTD 722
                S +E+++VI++LK  K Q    I+ ++    + E I ++L + +   QEN+  + D
Sbjct: 2704 LKIISIEEMSVVIDDLKASKLQQDNQIQIIQQQLQESEQINSQLHSQVENYQENIKQIQD 2763

Query: 723  KLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLE 782
             LE++  EK  E+    N  EQ++   Q  I   +Q+ +   +N + ++++  +     +
Sbjct: 2764 TLEQLKQEK-QEIT---NQSEQTEKDLQLEIQKLLQQIEEQNQNFQVQINELSNLGANNK 2819

Query: 783  ESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLL 842
              I   ++ + +++   DQL +     ++       + +EL  ++    + +  ++ Q  
Sbjct: 2820 LVIQEKQELQKNIQDLKDQLKTTQSNNKQTIQSLQAKIEELTTQICQQNELNNQLKSQNQ 2879

Query: 843  EIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKA-----------NRTDLAES 891
            +  H+ +EL  KN  L   N+ L+  +  ++Q  N++ EK            N+ +  + 
Sbjct: 2880 QNIHQIEELNIKNNFL---NKTLKEQVEQLEQELNSVQEKLEEKNKISKEQQNQFEALQE 2936

Query: 892  ESTKYQTQLRDLESNLKRITHEHQTL-----IVQKKKEIEDLEIEFNTQIESAIRDK-KV 945
               +   +++DL+ N +   H+ Q L     + +K+  ++  +I   T+  + +R++  V
Sbjct: 2937 NCVQLNQKIQDLQLNKQNQEHQIQQLQNQLNVFEKENLLQKEQISAKTKEANGLREELDV 2996

Query: 946  LNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTE 1005
            +N   +KN+E  T+   QLQE+   +E +     E N++  EL  +  Q   +       
Sbjct: 2997 INS--QKNLEQ-TESSKQLQEFCQQMETIT---REKNQIKQEL--EQFQLDSSNQSKSER 3048

Query: 1006 QYINEINKLNALLKQKDE-EIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEM 1064
            Q IN++    A +KQ+++ + + L +   N ++       + + ++ Q  + L+  +E  
Sbjct: 3049 QQINQLESELAQIKQREQKQKVILEENSKNHKIEK----EELQQQIKQVNSVLKAEQENF 3104

Query: 1065 QRVSKQLLDS-KQHNEELQILVREQDD-----QIKELKETKLTFEMNIPKTEGMIISSTI 1118
             +  K L    K H+E+++ L  EQ        +K  +   L  +M   + +   +S  I
Sbjct: 3105 IQKEKSLNQVIKGHSEQIEQLSNEQKALQNQLNLKNQEIAGLILQMKNKEEQQQQLSQKI 3164

Query: 1119 EPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKI-IQ 1177
              ++ D +N+             +K+Q  E+ I+E   LQE +   + +L +  +K+  Q
Sbjct: 3165 VQLNQDISNI--------TEQSNIKIQNGEKLIEE---LQELNNSNHEKLNDLESKLKAQ 3213

Query: 1178 LETLNTELTGHDV-VNQEQINQLK-----SKLEQLNTENDNLLSTVAELRSSISSAVDQR 1231
             +T+ +  + +   + Q Q N  K     S+LE+ N EN  L+    +    I++  ++ 
Sbjct: 3214 QQTIKSSASEYQKNIKQLQDNLQKQTNVNSELEKQNQENLKLIKQKDKQLEEINTQKEKM 3273

Query: 1232 GFEIAELWKQHLAQREADFQKTEHELRVQLSAFES--KYEQLLDSVQSSTQEETNKIVTM 1289
              +  E  +Q     +  +Q+ + EL+  L   E+  K EQ + +   + +EE +K++  
Sbjct: 3274 SSQYQEEKEQSQIINKK-YQQQDQELKQLLVKLENYEKQEQEIKNKLINVEEEKSKLIDS 3332

Query: 1290 EQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXX 1349
            + +  L+ K+ + EEH++ +QE+++    + E  ++E+                      
Sbjct: 3333 QNI--LEVKVLNLEEHIKRIQEEHSCKTKEFENKQNELLQSNTLLSKQSANLEDVYKQFE 3390

Query: 1350 X---DLRTENQ---SYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVL 1403
                DL    Q     KQ +E +I N+ E   QL   +             + +      
Sbjct: 3391 LKQNDLLNLIQLLEKEKQEKESAIQNLEEIKKQLISQNKQNQEKLNQAEADLKNQVQLNK 3450

Query: 1404 ELTH---QLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIED---LTYEKES 1457
            EL +   QLE   SE+  K  + T       D+ + ++ Q+ +  K+I        E +S
Sbjct: 3451 ELDNSKIQLEKMLSELQNKIEQNTQNANSMKDQLKKLQIQVDDQNKQINSEKAKADELKS 3510

Query: 1458 ELAILRLKMHENANHYETMQKESEIERVK---LIEEL-NVKIT------ESVSLNKQVAE 1507
             +     K+ E  N    + KE   E+     L E+  N K+       E+++ +    E
Sbjct: 3511 TIENQVQKISELQNKNNQISKELNQEKASAQDLKEQFNNQKLVLEQQQKENINTSNNFKE 3570

Query: 1508 LNKALEEEVAKTNEMQTALENQEIEIVTLND-EITNLQNMVRASSSKIQKHVSFASDTKQ 1566
             NK L+E+V         L+ Q  ++   +  E+    +++    SKI+     +S+ ++
Sbjct: 3571 TNKQLQEQVKLLQSEINQLKQQNDKLNDKHQKELLTQVSILEELQSKIKSQTEQSSNYQE 3630

Query: 1567 GRDEQLD-NTMNKELLDAVPRAELDL-AMYMLHQRD 1600
               +  D N  N++++D +     DL   ++L Q +
Sbjct: 3631 QIKQLSDKNIQNEQVIDQLLCKSKDLETKFILEQEE 3666



 Score =  159 bits (386), Expect = 6e-37
 Identities = 290/1527 (18%), Positives = 649/1527 (42%), Gaps = 148/1527 (9%)

Query: 156  NALSVLQVKMKIMETTILDLQEKINEK-----DQIIEAKNKATTXXXXXXXXXXXXXXXX 210
            N L  L++  + + TTI D Q + N+K      + I    K                   
Sbjct: 1709 NQLESLKIDNEKLNTTI-DQQNQDNQKINASMQETINKLQKENEQLQKELMDKISKFQTQ 1767

Query: 211  XEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLE 270
                +Q++T+  E+++ ++ E  +++  L++D+++ +++I   +E N+ L     E   E
Sbjct: 1768 IMSQEQKITQSDEDYLLLQEEL-NQQNILIQDLQN-ELKIQ--QEKNQELILKLNEQQSE 1823

Query: 271  HSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIEL 330
            ++KL +   +              L     E   E+   +++   L   +   L K  E+
Sbjct: 1824 YAKLIEVSGESEEKVKKSRKEQSNLQVSYNEVLNEKNILLQKLEELHQQSNINL-KNYEV 1882

Query: 331  LEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLS 390
             +    Q+ Q  ++LEN   TM  + K +       + L   K+  + +   K+  SQL 
Sbjct: 1883 TKQSLDQVIQERQQLENANQTMQNQIKKLEE-----NHLAQSKNYEDQSQNFKNQVSQLE 1937

Query: 391  SETLNQ--DTDKKINK------NEIAKLEMVIQSLNKDLVDKEYVISE--KDTXXXXXXX 440
             E  N+     KK+ +      N+I KLE  I+SL   + +KE +I +  K         
Sbjct: 1938 LELENERESNKKKVEQIQLGYENQIVKLEKQIESL---IGEKEILIEQVNKVQEERDIEK 1994

Query: 441  XXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDV-NVK 499
                K   + Q+ +E +Q         +  N E   +  K +EQ+   L  ++ D+ N++
Sbjct: 1995 NENLKKIELNQINIEEKQQKINNLQEEIQQNQEQFMQTIKQKEQIILNLRVQVDDISNLQ 2054

Query: 500  DLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVR 559
            + I +L+ A ++  Q+ D+I+  N   I     ++  L Q  + +   +K++   +E+ +
Sbjct: 2055 EQISQLQDALQEKQQIIDQIEKENIQQI-----YEETLIQKNELLSINNKLNQEKQELQK 2109

Query: 560  LTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLL 619
              E   +++Q++ +   +  +LQ   ++ +    +E    K   + + +AE  ++ I +L
Sbjct: 2110 AIE---NINQEIQQKSNQIDHLQT--LNNEIKTELEQKNGKIKSQEDQIAEN-IQNIQVL 2163

Query: 620  ESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELA 679
             ++   L +E  +    Y     K  +I Q+       E +   LE  I       + L 
Sbjct: 2164 NTENNQLKEEFSLKLNAY-----KSENIEQINQLTAVFENEKTQLENAIKQQKEINQNLE 2218

Query: 680  LVIEN-----LKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISE 734
              + N     +K+ +E      + +E  K +    L+   ++ ++L ++ E    E  ++
Sbjct: 2219 NQVVNQNQNIIKMQQENQLIQSESIEKQKREFTELLKQQDEKLLNLRNQFEDSKEE--NQ 2276

Query: 735  LLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYS 794
            LL + N ++   IQ    +  +IQ     ++N+ +E S  ++      E I  ++  R  
Sbjct: 2277 LLREQNEQKNQNIQQ---LQQEIQSLQQQLDNLINETSILRTEN---SEQIQNLKKEREE 2330

Query: 795  LERKADQLGSYLQEKQK--AYSEYTIQ--EDELVNRLAVLMDHDRVVEKQLLEIEHENKE 850
               K +QL   + + +K  A  +  +Q  ++EL ++LA+++   ++    + E+    ++
Sbjct: 2331 FLLKMEQLVEAINKLKKTSANDKQIMQKEQEELQSKLALVVSQAQINVNTIDELRQTKQQ 2390

Query: 851  LQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKR- 909
            L+  +Q+LL   Q   ++L           E   +  + E E   ++  +  LE  L   
Sbjct: 2391 LE--DQVLLLTKQADSLTLQSKMSESQFTEEMKKQILIFEQEKINFEKTISQLEQKLAEN 2448

Query: 910  ---ITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQE 966
                +++ Q L  +++K +  L+ E+    ++  +  ++  +  ++  E   + + Q++E
Sbjct: 2449 ELDSSNQIQLLQEEQQKIVNQLQ-EYKNMYQTERQQNELNTQSLQQQFEICERQKLQIEE 2507

Query: 967  YKNNIENL-NMNVEELNKMNLELIDKHVQKQ--QTQSPDYTEQYINEINKLNALLKQKDE 1023
             +  +E++   N E  N+ N   + K   +Q  + Q  ++ ++  +   KL   +K  + 
Sbjct: 2508 IQQRLEDIVEQNKETKNEYNELSVQKMSLEQLFEEQRGEFIKES-DRNQKLENAIKNLES 2566

Query: 1024 EIIALNQKINNAQVSYMSMVSDYES---KLAQFTTKLENMEEEMQRVSKQL--LDSKQHN 1078
            E  +L  K++N   +Y + + + E+   K  Q+  + ++++E+      ++  LD  + +
Sbjct: 2567 ENKSLKDKLDNLDQNYSNQILEIENERNKCLQYEHENQSLQEKCFSYQNKITELDETKKS 2626

Query: 1079 -----EELQILVREQDDQIKELK-ETKLTFEMN--IPKTEGMIISSTIEPMSD--DANNV 1128
                 EE +I ++++   ++ LK E +   + N  + K    II + +    D  +  N 
Sbjct: 2627 LIRQLEEFKIQIKDEQSTVQTLKLEIQKLIKQNEDLQKENQDIIENQVNAQLDILEKQNF 2686

Query: 1129 DXXXXXXXXXXXXLKVQEEEEFIQERSVLQE--QSAKL--NTELQECYTKIIQLETLNTE 1184
            D             +++ +   I+E SV+ +  +++KL  + ++Q    ++ + E +N++
Sbjct: 2687 DLQQLAQFNNQIKEELKLKIISIEEMSVVIDDLKASKLQQDNQIQIIQQQLQESEQINSQ 2746

Query: 1185 LTGHDVVNQEQINQLKSKLEQLNTENDNLLS----TVAELRSSISSAVDQ-----RGF-- 1233
            L       QE I Q++  LEQL  E   + +    T  +L+  I   + Q     + F  
Sbjct: 2747 LHSQVENYQENIKQIQDTLEQLKQEKQEITNQSEQTEKDLQLEIQKLLQQIEEQNQNFQV 2806

Query: 1234 ---EIAELWKQH--LAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVT 1288
               E++ L   +  + Q + + QK   +L+ QL   +S  +Q + S+Q+  +E T +I  
Sbjct: 2807 QINELSNLGANNKLVIQEKQELQKNIQDLKDQLKTTQSNNKQTIQSLQAKIEELTTQICQ 2866

Query: 1289 MEQVTSL------QNKLQDKEEHLRN------LQEKYADVINQIEILRSEIEDE-KVAFX 1335
              ++ +       QN  Q +E +++N      L+E+   +  ++  ++ ++E++ K++  
Sbjct: 2867 QNELNNQLKSQNQQNIHQIEELNIKNNFLNKTLKEQVEQLEQELNSVQEKLEEKNKISKE 2926

Query: 1336 XXXXXXXXXXXXXXXDLRTEN-QSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXR 1394
                           + + ++ Q  KQ QE  I  +  +    +K +             
Sbjct: 2927 QQNQFEALQENCVQLNQKIQDLQLNKQNQEHQIQQLQNQLNVFEKENLLQKEQISAKTKE 2986

Query: 1395 VNDAEAKVLELTHQLELKDSEIYQKTHEY-----TIT-----LTQRNDEFE--------N 1436
             N    ++  +  Q  L+ +E  ++  E+     TIT     + Q  ++F+        +
Sbjct: 2987 ANGLREELDVINSQKNLEQTESSKQLQEFCQQMETITREKNQIKQELEQFQLDSSNQSKS 3046

Query: 1437 VRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEE-LNVKI 1495
             RQQ+ + E  +  +   ++ +  IL     EN+ +++ ++KE   +++K +   L  + 
Sbjct: 3047 ERQQINQLESELAQIKQREQKQKVIL----EENSKNHK-IEKEELQQQIKQVNSVLKAEQ 3101

Query: 1496 TESVSLNKQVAELNKALEEEVAKTNEMQTALENQ-EIEIVTLNDEITNLQNMVRASSSKI 1554
               +   K + ++ K   E++ + +  Q AL+NQ  ++   +   I  ++N         
Sbjct: 3102 ENFIQKEKSLNQVIKGHSEQIEQLSNEQKALQNQLNLKNQEIAGLILQMKNKEEQQQQLS 3161

Query: 1555 QKHVSFASDTKQGRDEQLDNTMNKELL 1581
            QK V    D     ++      N E L
Sbjct: 3162 QKIVQLNQDISNITEQSNIKIQNGEKL 3188



 Score =  158 bits (384), Expect = 1e-36
 Identities = 269/1347 (19%), Positives = 582/1347 (43%), Gaps = 112/1347 (8%)

Query: 297  KQSIEPSCEEKTEIEEKGSLEIANMTELTKKI-ELLEHLNCQIRQTNKELENKLATMGTE 355
            K+++E   +E +E  E+   EI    +L + + E ++     I Q  ++      T+   
Sbjct: 1560 KENLERQLKEMSEQIEQQEQEIQQQQQLIELLHEQIQEKENIISQDQQKFNEATQTIKQN 1619

Query: 356  SKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKN------EIAK 409
             +   +  K+   ++S+ +   T    KS   Q+     NQ+  + + KN      +I  
Sbjct: 1620 EQEYLNLKKQLDDVVSKNNKLETELYEKSQQIQIRGNE-NQELIQNLQKNNQQLEQDILD 1678

Query: 410  LEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVG 469
             +     LN  + D +   SEK+T                 +L     Q  +    I+  
Sbjct: 1679 YKKKEDELNLLIKDLQQKSSEKETQLQINFNQLESLKIDNEKLNTTIDQQNQDNQKINAS 1738

Query: 470  TNTEDVNEIAKVQEQLKQELNDEIK--DVNVKDLIEKLKSAEEQITQLNDEIDAANKNMI 527
               E +N++ K  EQL++EL D+I      +    +K+  ++E    L +E++   +N++
Sbjct: 1739 MQ-ETINKLQKENEQLQKELMDKISKFQTQIMSQEQKITQSDEDYLLLQEELN--QQNIL 1795

Query: 528  KVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVD 587
                 ++LK++Q +K  +   K+++   E  +L E      +KV +  +E+ NLQ   V 
Sbjct: 1796 IQDLQNELKIQQ-EKNQELILKLNEQQSEYAKLIEVSGESEEKVKKSRKEQSNLQ---VS 1851

Query: 588  YDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADI 647
            Y+     ++ + +K+ E+   +   LK   + +     ++QE   L+     ++++   I
Sbjct: 1852 YNEVLNEKNILLQKLEELHQQSNINLKNYEVTKQSLDQVIQERQQLENANQTMQNQ---I 1908

Query: 648  SQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIK-DLENDKEDI 706
             +L+ + +    +S + E+Q         +L L +EN +   ++    I+   EN    +
Sbjct: 1909 KKLEENHLA---QSKNYEDQSQNFKNQVSQLELELENERESNKKKVEQIQLGYENQIVKL 1965

Query: 707  MNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQ-TQFGIDAKIQERDLYIE 765
              ++++ I E   L +++ K+  E+  E      +E   KI+  Q  I+ K Q+ +   E
Sbjct: 1966 EKQIESLIGEKEILIEQVNKVQEERDIE-----KNENLKKIELNQINIEEKQQKINNLQE 2020

Query: 766  NIESELSKYKSRICRLEE---SIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDE 822
             I+    ++   I + E+   ++ V  D   +L+ +  QL   LQEKQ+   +    E E
Sbjct: 2021 EIQQNQEQFMQTIKQKEQIILNLRVQVDDISNLQEQISQLQDALQEKQQIIDQI---EKE 2077

Query: 823  LVNRLAVLMDHDRVVEKQLLEIEHE-NKELQKKNQILLEENQNLQISLSDMQQHYNALVE 881
             + ++    +   + + +LL I ++ N+E Q+  + +   NQ +Q   S+   H   L  
Sbjct: 2078 NIQQI---YEETLIQKNELLSINNKLNQEKQELQKAIENINQEIQ-QKSNQIDHLQTLNN 2133

Query: 882  KANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIR 941
            +  +T+L E ++ K ++Q   +  N++ I    Q L  +  +  E+  ++ N      I 
Sbjct: 2134 EI-KTEL-EQKNGKIKSQEDQIAENIQNI----QVLNTENNQLKEEFSLKLNAYKSENIE 2187

Query: 942  DKKVLNEKYEKNIEYVTQLEAQLQEYKNNIEN----LNMNVEELNKMNLELIDKHVQKQQ 997
                L   +E     +     Q +E   N+EN     N N+ ++ + N  +  + ++KQ+
Sbjct: 2188 QINQLTAVFENEKTQLENAIKQQKEINQNLENQVVNQNQNIIKMQQENQLIQSESIEKQK 2247

Query: 998  TQSPDYTEQYINEINKL----------NALLK----QKDEEIIALNQKINNAQVSYMSMV 1043
             +  +  +Q   ++  L          N LL+    QK++ I  L Q+I + Q    +++
Sbjct: 2248 REFTELLKQQDEKLLNLRNQFEDSKEENQLLREQNEQKNQNIQQLQQEIQSLQQQLDNLI 2307

Query: 1044 SDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVR--EQDDQIKELKETKLT 1101
            ++      + + +++N+++E +     LL  +Q  E +  L +    D QI + ++ +L 
Sbjct: 2308 NETSILRTENSEQIQNLKKEREEF---LLKMEQLVEAINKLKKTSANDKQIMQKEQEELQ 2364

Query: 1102 FEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQ---EEEEFIQE--RSV 1156
             ++ +  ++  I  +TI+ +      ++            L +Q    E +F +E  + +
Sbjct: 2365 SKLALVVSQAQINVNTIDELRQTKQQLEDQVLLLTKQADSLTLQSKMSESQFTEEMKKQI 2424

Query: 1157 LQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQ-INQLKSKLEQLNTENDNLLS 1215
            L  +  K+N E       I QLE    E    D  NQ Q + + + K+     E  N+  
Sbjct: 2425 LIFEQEKINFE-----KTISQLEQKLAE-NELDSSNQIQLLQEEQQKIVNQLQEYKNMYQ 2478

Query: 1216 TVAELRSSISSAVDQRGFEIAELWK---QHLAQREADFQKTEHELR---VQLSAFESKYE 1269
            T  + ++ +++   Q+ FEI E  K   + + QR  D  +   E +    +LS  +   E
Sbjct: 2479 TERQ-QNELNTQSLQQQFEICERQKLQIEEIQQRLEDIVEQNKETKNEYNELSVQKMSLE 2537

Query: 1270 QLLDSVQSSTQEETNKIVTMEQ-VTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSE-I 1327
            QL +  +    +E+++   +E  + +L+++ +  ++ L NL + Y++ I +IE  R++ +
Sbjct: 2538 QLFEEQRGEFIKESDRNQKLENAIKNLESENKSLKDKLDNLDQNYSNQILEIENERNKCL 2597

Query: 1328 EDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXX 1387
            + E                    D  T+    +Q++E  I  I +E + ++         
Sbjct: 2598 QYEHENQSLQEKCFSYQNKITELD-ETKKSLIRQLEEFKI-QIKDEQSTVQ----TLKLE 2651

Query: 1388 XXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEF-ENVRQQLVEYEK 1446
                  +  D + +  ++         +I +K +     L Q N++  E ++ +++  E+
Sbjct: 2652 IQKLIKQNEDLQKENQDIIENQVNAQLDILEKQNFDLQQLAQFNNQIKEELKLKIISIEE 2711

Query: 1447 R---IEDLTYEK---ESELAIL--RLKMHENANHYETMQKESEIERVKLIEE-LNVKITE 1497
                I+DL   K   ++++ I+  +L+  E  N     Q E+  E +K I++ L     E
Sbjct: 2712 MSVVIDDLKASKLQQDNQIQIIQQQLQESEQINSQLHSQVENYQENIKQIQDTLEQLKQE 2771

Query: 1498 SVSLNKQVAELNKALEEEVAK-TNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQK 1556
               +  Q  +  K L+ E+ K   +++   +N +++I  L++   N   +V     ++QK
Sbjct: 2772 KQEITNQSEQTEKDLQLEIQKLLQQIEEQNQNFQVQINELSNLGAN-NKLVIQEKQELQK 2830

Query: 1557 HVSFASD---TKQGRDEQLDNTMNKEL 1580
            ++    D   T Q  ++Q   ++  ++
Sbjct: 2831 NIQDLKDQLKTTQSNNKQTIQSLQAKI 2857



 Score =  156 bits (378), Expect = 5e-36
 Identities = 257/1410 (18%), Positives = 599/1410 (42%), Gaps = 115/1410 (8%)

Query: 216  QQMTKMQENFIAM-EAEWKDEKQRLLKDIE-----SKDVRISSLEEANKLLEAARFEISL 269
            +QM  ++EN+  + E    D    +L  I      SK  ++ ++ E NK L      +S 
Sbjct: 987  EQMKNLKENYEKLIEQHQNDSMSNILHQINGGSSPSKSDQLVTVMETNKKLIEEMASLSD 1046

Query: 270  EHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIE 329
             + KL  E+E                 +         K+++E++  L  A M ++ +  +
Sbjct: 1047 MNKKLMDEIEMLRNMSHSRLDISSTFERNGDNEVL--KSKLEKQTELNEALMQQMKEMKQ 1104

Query: 330  LLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGR-NTASKMKSPWSQ 388
              E    Q  Q N+           + +  S   KK   L+ ++  R     K ++    
Sbjct: 1105 HYESTLSQQSQQNQVTLQNQQQFTKQKQLFSEQVKKLEELLKKQQDRIEELEKEQADLQL 1164

Query: 389  LSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTL 448
            L ++ +N ++ +K+      + + ++ S N+ L ++   + +++            +   
Sbjct: 1165 LQAQRMNMESKEKLMNQNKQQFDQLL-STNQRLSEQVLNLQQQNQQLQQEVDELRNRSM- 1222

Query: 449  IAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELN--DEIKDVNVKDLIEKLK 506
                   +Q  M   S I +  N + + ++ +    L +++    +++  ++  +     
Sbjct: 1223 -------YQSIMTDRSSIQIAHN-DRIEQLQEENRILSEQIVALSKVQRNSLPPIEGNST 1274

Query: 507  SAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHH 566
             ++ +  +L+D +   N+ +++V  N KL  + +QK      K     +E+  L      
Sbjct: 1275 VSKNEAIKLHD-LQEQNERILRV--NQKLLTENLQKG----EKEVHMKRELEDLKSR-SQ 1326

Query: 567  LSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDL 626
            LS  ++ + +E+   +L  +  +     E ++ +   E++   +        L  +   L
Sbjct: 1327 LSMSMSYIHDEEEQSKLRKILQEQVLSYEIEIKQVQNELQESKKQFSHEKESLNKEIQQL 1386

Query: 627  VQELHILQQKYDEVEDKLADISQL--QSDQVCSEIKSVHLEEQIDALSASKKELALVIEN 684
                H+L Q+  E E ++  I  L  Q+ Q   + ++  L+ QI  L+    +  L  EN
Sbjct: 1387 KNNAHLLNQQVQEKEIQIKQIENLTTQNIQKQYQYENAILKAQIIQLNEEISQQKLKCEN 1446

Query: 685  LKLDKEQLYGTIKDLENDKEDIMN--KLQNYIQEN----MDLTDKLEKMSAEKISELLAK 738
            +           K  EN +E  +N  +LQ+ ++E     ++L D+++++  EK ++L   
Sbjct: 1447 IS----------KQNENSQEINLNLIQLQDSLKEKEILIINLEDQVKQLQLEK-NKLFQ- 1494

Query: 739  INHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERK 798
             + EE   I +Q     K+  +    E +++EL+   ++I  L+  +  +  +    ER 
Sbjct: 1495 -SSEELKVIHSQQVNQLKLSSQQ-QCEQLKNELN---TQILDLQNQVNQLLQKN---ERL 1546

Query: 799  ADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQIL 858
            A+Q   Y+Q++Q+       Q  E+  ++    + +   ++QL+E+ HE  ++Q+K  I+
Sbjct: 1547 ANQNSEYIQDQQEK-ENLERQLKEMSEQIEQ-QEQEIQQQQQLIELLHE--QIQEKENII 1602

Query: 859  LEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLI 918
             ++ Q    +   ++Q+    +    + D   S++ K +T+L +    ++   +E+Q LI
Sbjct: 1603 SQDQQKFNEATQTIKQNEQEYLNLKKQLDDVVSKNNKLETELYEKSQQIQIRGNENQELI 1662

Query: 919  VQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEA---QLQEYKNNIENLN 975
               +K  + LE +     +       ++ +  +K+ E  TQL+    QL+  K + E LN
Sbjct: 1663 QNLQKNNQQLEQDILDYKKKEDELNLLIKDLQQKSSEKETQLQINFNQLESLKIDNEKLN 1722

Query: 976  MNVEELNKMNLEL---IDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKI 1032
              +++ N+ N ++   + + + K Q ++    ++ +++I+K          +I++  QKI
Sbjct: 1723 TTIDQQNQDNQKINASMQETINKLQKENEQLQKELMDKISKFQT-------QIMSQEQKI 1775

Query: 1033 NNAQVSYMSMVSDYESK---LAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQD 1089
              +   Y+ +  +   +   +     +L+  +E+ Q +  +L + +    +L  +  E +
Sbjct: 1776 TQSDEDYLLLQEELNQQNILIQDLQNELKIQQEKNQELILKLNEQQSEYAKLIEVSGESE 1835

Query: 1090 DQIKELK--ETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEE 1147
            +++K+ +  ++ L    N    E  I+   +E +    +N++              +QE 
Sbjct: 1836 EKVKKSRKEQSNLQVSYNEVLNEKNILLQKLEELHQQ-SNINLKNYEVTKQSLDQVIQER 1894

Query: 1148 EEFIQERSVLQEQSAKL-NTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQL 1206
            ++       +Q Q  KL    L +      Q +    +++  ++  + +    K K+EQ+
Sbjct: 1895 QQLENANQTMQNQIKKLEENHLAQSKNYEDQSQNFKNQVSQLELELENERESNKKKVEQI 1954

Query: 1207 NTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFE- 1265
                +N    + +L   I S + ++   I ++ K    Q E D +K E+  +++L+    
Sbjct: 1955 QLGYEN---QIVKLEKQIESLIGEKEILIEQVNK---VQEERDIEKNENLKKIELNQINI 2008

Query: 1266 SKYEQLLDSVQSSTQEETNKIV-TMEQVTSLQNKLQDKEEHLRNLQEKYA---DVINQIE 1321
             + +Q ++++Q   Q+   + + T++Q   +   L+ + + + NLQE+ +   D + + +
Sbjct: 2009 EEKQQKINNLQEEIQQNQEQFMQTIKQKEQIILNLRVQVDDISNLQEQISQLQDALQEKQ 2068

Query: 1322 ILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQ----- 1376
             +  +IE E +                   +  +    KQ  +++I NIN+E  Q     
Sbjct: 2069 QIIDQIEKENI---QQIYEETLIQKNELLSINNKLNQEKQELQKAIENINQEIQQKSNQI 2125

Query: 1377 --LKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITL-TQRNDE 1433
              L+  +            ++   E ++ E    +++ ++E  Q   E+++ L   +++ 
Sbjct: 2126 DHLQTLNNEIKTELEQKNGKIKSQEDQIAENIQNIQVLNTENNQLKEEFSLKLNAYKSEN 2185

Query: 1434 FENVRQQLVEYEK---RIED-LTYEKESELAILRLKMHENANHYETMQKESEIERVKLIE 1489
             E + Q    +E    ++E+ +  +KE    +    +++N N  + MQ+E+++ + + IE
Sbjct: 2186 IEQINQLTAVFENEKTQLENAIKQQKEINQNLENQVVNQNQNIIK-MQQENQLIQSESIE 2244

Query: 1490 ELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRA 1549
            +   + TE   L KQ  E    L  +   + E    L  Q  +    N  I  LQ  +++
Sbjct: 2245 KQKREFTE---LLKQQDEKLLNLRNQFEDSKEENQLLREQNEQ---KNQNIQQLQQEIQS 2298

Query: 1550 SSSKIQKHVSFASDTKQGRDEQLDNTMNKE 1579
               ++   ++  S  +    EQ+ N + KE
Sbjct: 2299 LQQQLDNLINETSILRTENSEQIQN-LKKE 2327



 Score =  148 bits (359), Expect = 1e-33
 Identities = 261/1240 (21%), Positives = 551/1240 (44%), Gaps = 158/1240 (12%)

Query: 214  TKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSK 273
            T++Q  ++    +  + E   E+Q+L   IE    R+  + E NK  +    E+S++   
Sbjct: 2479 TERQQNELNTQSLQQQFEIC-ERQKL--QIEEIQQRLEDIVEQNKETKNEYNELSVQKMS 2535

Query: 274  LAQELEQXXXXXXXXXXXXXXLAK-----QSIEPSCEEKTE-IEEKGSLEIANMTELTKK 327
            L Q  E+              L       +S   S ++K + +++  S +I  +     K
Sbjct: 2536 LEQLFEEQRGEFIKESDRNQKLENAIKNLESENKSLKDKLDNLDQNYSNQILEIENERNK 2595

Query: 328  IELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWS 387
                EH N  +++     +NK+  +    K++    ++    I  K  ++T   +K    
Sbjct: 2596 CLQYEHENQSLQEKCFSYQNKITELDETKKSLIRQLEEFK--IQIKDEQSTVQTLKLEIQ 2653

Query: 388  QL--SSETL---NQDT-DKKINKN---------EIAKLEMVIQSLNKDLVDKEYVISEKD 432
            +L   +E L   NQD  + ++N           ++ +L      + ++L  K   I E  
Sbjct: 2654 KLIKQNEDLQKENQDIIENQVNAQLDILEKQNFDLQQLAQFNNQIKEELKLKIISIEEMS 2713

Query: 433  TXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIH--VGTNTEDVNEIAKVQEQLKQELN 490
                        +D  I  +Q + Q+  +  S +H  V    E++ +I    EQLKQE  
Sbjct: 2714 VVIDDLKASKLQQDNQIQIIQQQLQESEQINSQLHSQVENYQENIKQIQDTLEQLKQEKQ 2773

Query: 491  D--EIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFS 548
            +     +   KDL  +++   +QI + N         +  + +N+KL +++ Q+   N  
Sbjct: 2774 EITNQSEQTEKDLQLEIQKLLQQIEEQNQNFQVQINELSNLGANNKLVIQEKQELQKNIQ 2833

Query: 549  KVSDSNKEIVRLTEE-LHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMEN 607
             + D  K      ++ +  L  K+ EL  +    Q + ++       + ++++  IE  N
Sbjct: 2834 DLKDQLKTTQSNNKQTIQSLQAKIEELTTQI--CQQNELNNQLKSQNQQNIHQ--IEELN 2889

Query: 608  LAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQ 667
            +    L     L+ Q   L QEL+ +Q+K +E ++K++   Q Q + +  +   V L ++
Sbjct: 2890 IKNNFLN--KTLKEQVEQLEQELNSVQEKLEE-KNKISKEQQNQFEAL--QENCVQLNQK 2944

Query: 668  IDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKM 727
            I  L  +K+     I+ L+ ++  ++     L+ ++     K  N ++E +D+ +  + +
Sbjct: 2945 IQDLQLNKQNQEHQIQQLQ-NQLNVFEKENLLQKEQISAKTKEANGLREELDVINSQKNL 3003

Query: 728  SAEKISELLAKINHE------EQSKIQT---QFGIDAKIQERD--LYIENIESELSKYKS 776
               + S+ L +   +      E+++I+    QF +D+  Q +     I  +ESEL++ K 
Sbjct: 3004 EQTESSKQLQEFCQQMETITREKNQIKQELEQFQLDSSNQSKSERQQINQLESELAQIKQ 3063

Query: 777  RICR----LEESIAVMEDRRYSLERKADQLGSYLQ-------EKQKAYSE----YTIQED 821
            R  +    LEE+    +  +  L+++  Q+ S L+       +K+K+ ++    ++ Q +
Sbjct: 3064 REQKQKVILEENSKNHKIEKEELQQQIKQVNSVLKAEQENFIQKEKSLNQVIKGHSEQIE 3123

Query: 822  ELVNRLAVLMDHDRVVEKQL----LEIEHENKELQKKNQILLEENQ---------NLQIS 868
            +L N    L +   +  +++    L+++++ ++ Q+ +Q +++ NQ         N++I 
Sbjct: 3124 QLSNEQKALQNQLNLKNQEIAGLILQMKNKEEQQQQLSQKIVQLNQDISNITEQSNIKIQ 3183

Query: 869  -----LSDMQQHYNALVEKAN--------RTDLAESESTKYQTQLRDLESNLKRITH--- 912
                 + ++Q+  N+  EK N        +    +S +++YQ  ++ L+ NL++ T+   
Sbjct: 3184 NGEKLIEELQELNNSNHEKLNDLESKLKAQQQTIKSSASEYQKNIKQLQDNLQKQTNVNS 3243

Query: 913  -------EHQTLIVQKKKEIEDLEIE---FNTQIESAIRDKKVLNEKYEKNIEYVTQLEA 962
                   E+  LI QK K++E++  +    ++Q +      +++N+KY++  + + QL  
Sbjct: 3244 ELEKQNQENLKLIKQKDKQLEEINTQKEKMSSQYQEEKEQSQIINKKYQQQDQELKQLLV 3303

Query: 963  QLQEYKNN---IENLNMNVEE-----LNKMN-LEL----IDKHVQKQQTQSPDYTEQYIN 1009
            +L+ Y+     I+N  +NVEE     ++  N LE+    +++H+++ Q +    T+++ N
Sbjct: 3304 KLENYEKQEQEIKNKLINVEEEKSKLIDSQNILEVKVLNLEEHIKRIQEEHSCKTKEFEN 3363

Query: 1010 EINKL---NALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQR 1066
            + N+L   N LL ++   +  + ++    Q   ++++   E +  +  + ++N+EE    
Sbjct: 3364 KQNELLQSNTLLSKQSANLEDVYKQFELKQNDLLNLIQLLEKEKQEKESAIQNLEE---- 3419

Query: 1067 VSKQLLD-SKQHNEELQILVREQDDQI---KELKETKLTFEMNIPKTEGMIISST--IEP 1120
            + KQL+  +KQ+ E+L     +  +Q+   KEL  +K+  E  + + +  I  +T     
Sbjct: 3420 IKKQLISQNKQNQEKLNQAEADLKNQVQLNKELDNSKIQLEKMLSELQNKIEQNTQNANS 3479

Query: 1121 MSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLET 1180
            M D    +              K + +E     +S ++ Q  K++ ELQ    +I + E 
Sbjct: 3480 MKDQLKKLQIQVDDQNKQINSEKAKADEL----KSTIENQVQKIS-ELQNKNNQISK-EL 3533

Query: 1181 LNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWK 1240
               + +  D+  +EQ N  K  LEQ   EN N  +   E    +   V     EI +L K
Sbjct: 3534 NQEKASAQDL--KEQFNNQKLVLEQQQKENINTSNNFKETNKQLQEQVKLLQSEINQL-K 3590

Query: 1241 QHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSST--QEE----TNKIVTMEQVTS 1294
            Q   Q +    K + EL  Q+S  E    ++    + S+  QE+    ++K +  EQV  
Sbjct: 3591 Q---QNDKLNDKHQKELLTQVSILEELQSKIKSQTEQSSNYQEQIKQLSDKNIQNEQVID 3647

Query: 1295 --------LQNKLQDKEEHLRNLQEKYADVINQIEILRSE 1326
                    L+ K   ++E  + L   Y + +NQ+E+ +SE
Sbjct: 3648 QLLCKSKDLETKFILEQEENQKLVNDYEEKMNQLELAKSE 3687



 Score =  123 bits (296), Expect = 5e-26
 Identities = 277/1549 (17%), Positives = 629/1549 (40%), Gaps = 110/1549 (7%)

Query: 55   ERAQKCLENAALVSKRIKEHRKATAELLGRPFVPGISESLANTLKQKEILMEKIKQYKE- 113
            E  +K L+N   ++K +++ ++   E   +     + E + +T++    ++E+IK+ +E 
Sbjct: 288  ESIRKELDNLIKINKSLQQDKEYQIEENSK-----LEEEIKSTIEIYTKMIEQIKESQED 342

Query: 114  -LSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNALSVLQVKMKIMETTI 172
               K  + +++                    V  L    +   N +  L+ +  +M+ T+
Sbjct: 343  NFHKNVNQSMILDQSLQVVYQIKEDNDLKRKVKVLMTDKEALQNKIKNLEFENNMMKQTM 402

Query: 173  LDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEW 232
            +  +E    + QI+ A N+                    +  +Q++ +    F   E ++
Sbjct: 403  IVPEEA---RSQILRATNQIKNGQEQIQELRRQIKQLEAQLREQKLNESFSEFRIYEQKY 459

Query: 233  KDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXX 292
            K+EK    K  E     I+ L++  +  + A  +I  + S +   +              
Sbjct: 460  KEEKILTTKLQEE----IALLKQGFQT-QGATSQILTQKSDMQSRMIGSKKIKGIASQSN 514

Query: 293  XXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATM 352
              +   S   + +   +     + EI ++ +L     L++ +   +++ N  L+ +++ +
Sbjct: 515  IQMPPLSQTLNVQGIKQSSSNSNQEIESLKKLNDS--LIKEIE-NLKRENSNLQVQVSRI 571

Query: 353  GTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEM 412
              +SK+  + +++ + L + K     +S+++SP SQ        D     +    A+  +
Sbjct: 572  NYDSKSSQNTAQRPNHLQNTKKPIQISSQLQSPVSQFKFG--GSDNANSNSNYHSAEKNL 629

Query: 413  VIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNT 472
              ++  + + D +  +                + TLI Q      ++++      +    
Sbjct: 630  DNKNQQQIINDLQTELEITKNQLKKIMQADSARKTLITQFDQTTNENLQN----QIIQKD 685

Query: 473  EDVNEIAKVQEQLKQEL-------NDEIKDVNVKDLIEK---LKSAEEQITQLNDEIDAA 522
              +N + K  + LK E        N E+  +N   ++E    L ++  Q T      ++ 
Sbjct: 686  ITINHLQKQLQMLKNEKDFNPNQGNLEMSFLNQSSILEDDLILPTSHGQQT-FRFYQESK 744

Query: 523  NKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTE----ELHHLSQKVAELEEE- 577
             K +I    N K+++ Q+Q +++   K +     I+  TE    E  +L  KV  L++E 
Sbjct: 745  EKEII----NLKMQIDQLQ-SMNRQKKENIMGLSILEDTEAIKSENAYLKAKVESLQKEL 799

Query: 578  --KGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQ 635
              K N++ H  + DS       + ++  E+       +  + +L++  +  + +L     
Sbjct: 800  QNKFNVKQHQAELDSLLQSNKKLIQENSELSQKNRKLMDELDILKNSSYSKI-DLSNAYD 858

Query: 636  KYDEVEDKLADI-SQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYG 694
            + +E+E+    +  Q + +Q+ ++      E     +    + ++ ++    + ++    
Sbjct: 859  RGNEIEELQKKLEKQTKINQILNKQMKEMQENHEQVIDLHNQSMSSILNPQSIQQK---N 915

Query: 695  TIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISEL-LAKINHEEQSKIQTQFGI 753
            ++  L    + I+ +     Q N  L ++L+ +     S+L ++ +  +       +  +
Sbjct: 916  SLASLLATNQKIIEENVQLAQMNKKLQEELDSIRNPSHSQLDISNVYEKANEASSLKRKL 975

Query: 754  DAKIQERDLYIENIESELSKYKSRICRLEE---SIAVMEDRRYSLERKADQLGSYLQEKQ 810
            D + Q   L  E +++    Y+  I + +    S  + +    S   K+DQL + ++  +
Sbjct: 976  DQQTQLNQLLTEQMKNLKENYEKLIEQHQNDSMSNILHQINGGSSPSKSDQLVTVMETNK 1035

Query: 811  KAYSEYTIQED---ELVNRLAVL--MDHDRVVEKQLLEIEHENKELQKKNQILLEENQNL 865
            K   E     D   +L++ + +L  M H R+      E   +N+ L+ K +   E N+ L
Sbjct: 1036 KLIEEMASLSDMNKKLMDEIEMLRNMSHSRLDISSTFERNGDNEVLKSKLEKQTELNEAL 1095

Query: 866  QISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEI 925
               + +M+QHY + + + ++ +    ++ +  T+ + L S   +   E   L+ +++  I
Sbjct: 1096 MQQMKEMKQHYESTLSQQSQQNQVTLQNQQQFTKQKQLFSEQVKKLEE---LLKKQQDRI 1152

Query: 926  EDLEIE-FNTQIESAIRDKKVLNEK-YEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNK 983
            E+LE E  + Q+  A R      EK   +N +   QL +  Q     + NL    ++L +
Sbjct: 1153 EELEKEQADLQLLQAQRMNMESKEKLMNQNKQQFDQLLSTNQRLSEQVLNLQQQNQQLQQ 1212

Query: 984  MNLELIDKHV-QKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSM 1042
               EL ++ + Q   T        + + I +L    +   E+I+AL+ K+    +  +  
Sbjct: 1213 EVDELRNRSMYQSIMTDRSSIQIAHNDRIEQLQEENRILSEQIVALS-KVQRNSLPPIEG 1271

Query: 1043 VSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTF 1102
             S      A     L+   E + RV+++LL       E ++ ++ + + +K   +  ++ 
Sbjct: 1272 NSTVSKNEAIKLHDLQEQNERILRVNQKLLTENLQKGEKEVHMKRELEDLKSRSQLSMSM 1331

Query: 1103 EMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSA 1162
                 + E   +   ++                          E+E   +E   L+  + 
Sbjct: 1332 SYIHDEEEQSKLRKILQEQVLSYEIEIKQVQNELQESKKQFSHEKESLNKEIQQLKNNAH 1391

Query: 1163 KLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRS 1222
             LN ++QE   +I Q+E L T+        +  I  LK+++ QLN E      +  +L+ 
Sbjct: 1392 LLNQQVQEKEIQIKQIENLTTQNIQKQYQYENAI--LKAQIIQLNEE-----ISQQKLKC 1444

Query: 1223 SISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQL-LDSVQSSTQE 1281
               S  ++   EI      +L Q     Q +  E  + +   E + +QL L+  +     
Sbjct: 1445 ENISKQNENSQEI----NLNLIQ----LQDSLKEKEILIINLEDQVKQLQLEKNKLFQSS 1496

Query: 1282 ETNKIVTMEQVTSLQNKLQDKEEHLRN-LQEKYADVINQIEILRSEIE----DEKVAFXX 1336
            E  K++  +QV  L+   Q + E L+N L  +  D+ NQ+  L  + E            
Sbjct: 1497 EELKVIHSQQVNQLKLSSQQQCEQLKNELNTQILDLQNQVNQLLQKNERLANQNSEYIQD 1556

Query: 1337 XXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXR-V 1395
                            + E Q  +  Q+Q ++ +  E  Q K++             + +
Sbjct: 1557 QQEKENLERQLKEMSEQIEQQEQEIQQQQQLIELLHEQIQEKENIISQDQQKFNEATQTI 1616

Query: 1396 NDAEAKVLELTHQLE-------LKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRI 1448
               E + L L  QL+         ++E+Y+K+ +  I   +  +  +N+++   + E+ I
Sbjct: 1617 KQNEQEYLNLKKQLDDVVSKNNKLETELYEKSQQIQIRGNENQELIQNLQKNNQQLEQDI 1676

Query: 1449 EDLTYEKESELAILRLKMHENANHYETMQK--ESEIERVKL-IEELNVKITESVSLNKQV 1505
             D   +KE EL +L   + + ++  ET  +   +++E +K+  E+LN  I +    N+  
Sbjct: 1677 LDYK-KKEDELNLLIKDLQQKSSEKETQLQINFNQLESLKIDNEKLNTTIDQQ---NQDN 1732

Query: 1506 AELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKI 1554
             ++N +++E +   N++Q   EN++++   L D+I+  Q  + +   KI
Sbjct: 1733 QKINASMQETI---NKLQK--ENEQLQ-KELMDKISKFQTQIMSQEQKI 1775



 Score = 99.1 bits (236), Expect = 9e-19
 Identities = 245/1243 (19%), Positives = 518/1243 (41%), Gaps = 117/1243 (9%)

Query: 398  TDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQL-QLEH 456
            TDK+  +N+I  LE     + + ++  E   S+                 L  Q+ QLE 
Sbjct: 379  TDKEALQNKIKNLEFENNMMKQTMIVPEEARSQILRATNQIKNGQEQIQELRRQIKQLEA 438

Query: 457  QQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLN 516
            Q  +    L    +      +  K ++ L  +L +EI    +K   +   +  + +TQ +
Sbjct: 439  Q--LREQKLNESFSEFRIYEQKYKEEKILTTKLQEEI--ALLKQGFQTQGATSQILTQKS 494

Query: 517  DEIDA--ANKNMIKVKSNHKLKLKQMQKTIDNFS---KVSDSNKEIVRLTEELHHLSQKV 571
            D       +K +  + S   +++  + +T++        S+SN+EI  L +    L +++
Sbjct: 495  DMQSRMIGSKKIKGIASQSNIQMPPLSQTLNVQGIKQSSSNSNQEIESLKKLNDSLIKEI 554

Query: 572  AELEEEKGNLQLHL--VDYDS-------GRMIESDVYKKMIEMENLAETRLKAISLLESQ 622
              L+ E  NLQ+ +  ++YDS        R       KK I++ +  ++ +       S 
Sbjct: 555  ENLKRENSNLQVQVSRINYDSKSSQNTAQRPNHLQNTKKPIQISSQLQSPVSQFKFGGSD 614

Query: 623  KFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELA--- 679
              +     H  ++  D  +++   I+ LQ++    EI    L++ + A SA K  +    
Sbjct: 615  NANSNSNYHSAEKNLDN-KNQQQIINDLQTE---LEITKNQLKKIMQADSARKTLITQFD 670

Query: 680  -LVIENLKLDKEQLYGTIKDLENDKEDIMNKLQ-NYIQENMDLTDKLEKMSAEKISELLA 737
                ENL+    Q   TI  L+   + + N+   N  Q N++++   +    E   +L+ 
Sbjct: 671  QTTNENLQNQIIQKDITINHLQKQLQMLKNEKDFNPNQGNLEMSFLNQSSILE--DDLIL 728

Query: 738  KINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICR---LEESIAVMEDRRY- 793
              +H +Q+    Q   + +I    + I+ ++S   + K  I     LE++ A+  +  Y 
Sbjct: 729  PTSHGQQTFRFYQESKEKEIINLKMQIDQLQSMNRQKKENIMGLSILEDTEAIKSENAYL 788

Query: 794  -----SLERKAD----------QLGSYLQEKQKAY---SEYTIQEDELVNRLAVLMD--H 833
                 SL+++            +L S LQ  +K     SE + +  +L++ L +L +  +
Sbjct: 789  KAKVESLQKELQNKFNVKQHQAELDSLLQSNKKLIQENSELSQKNRKLMDELDILKNSSY 848

Query: 834  DRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANR--TDLAES 891
             ++      +  +E +ELQKK +   + NQ L   + +MQ+++  +++  N+  + +   
Sbjct: 849  SKIDLSNAYDRGNEIEELQKKLEKQTKINQILNKQMKEMQENHEQVIDLHNQSMSSILNP 908

Query: 892  ESTKYQTQLRDLESNLKRITHEHQTLIVQKKK---EIEDLEIEFNTQIE-SAIRDKKVLN 947
            +S + +  L  L +  ++I  E+  L    KK   E++ +    ++Q++ S + +K    
Sbjct: 909  QSIQQKNSLASLLATNQKIIEENVQLAQMNKKLQEELDSIRNPSHSQLDISNVYEKANEA 968

Query: 948  EKYEKNIEYVTQLEAQLQEYKNNI-ENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQ 1006
               ++ ++  TQL   L E   N+ EN    +E+    ++  I  H Q     SP  ++Q
Sbjct: 969  SSLKRKLDQQTQLNQLLTEQMKNLKENYEKLIEQHQNDSMSNI-LH-QINGGSSPSKSDQ 1026

Query: 1007 YIN--EINKL----NALLKQKDEEIIALNQKINNAQVSYMSMVSDYE--SKLAQFTTKLE 1058
             +   E NK      A L   +++++   + + N   S + + S +E         +KLE
Sbjct: 1027 LVTVMETNKKLIEEMASLSDMNKKLMDEIEMLRNMSHSRLDISSTFERNGDNEVLKSKLE 1086

Query: 1059 NMEEEMQRVSKQLLDSKQHNEELQILVREQDDQI-----KELKETKLTFEMNIPKTEGMI 1113
               E  + + +Q+ + KQH E   +  + Q +Q+     ++  + K  F   + K E ++
Sbjct: 1087 KQTELNEALMQQMKEMKQHYES-TLSQQSQQNQVTLQNQQQFTKQKQLFSEQVKKLEELL 1145

Query: 1114 --ISSTIEPMSDDANNVDXXXXXXXXXXXXLKV--QEEEEFIQERSV----------LQE 1159
                  IE +  +  ++              K+  Q +++F Q  S           LQ+
Sbjct: 1146 KKQQDRIEELEKEQADLQLLQAQRMNMESKEKLMNQNKQQFDQLLSTNQRLSEQVLNLQQ 1205

Query: 1160 QSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAE 1219
            Q+ +L  E+ E   + +  +++ T+ +   + + ++I QL+ +  ++ +E    LS V  
Sbjct: 1206 QNQQLQQEVDELRNRSM-YQSIMTDRSSIQIAHNDRIEQLQEE-NRILSEQIVALSKVQ- 1262

Query: 1220 LRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSST 1279
             R+S+            E  K H  Q     ++ E  LRV         ++     +   
Sbjct: 1263 -RNSLPPIEGNSTVSKNEAIKLHDLQ-----EQNERILRVNQKLLTENLQK--GEKEVHM 1314

Query: 1280 QEETNKIVTMEQVTSLQNKLQDKEEH--LRN-LQEKYADVINQIEILRSEIEDEKVAFXX 1336
            + E   + +  Q++   + + D+EE   LR  LQE+      +I+ +++E+++ K  F  
Sbjct: 1315 KRELEDLKSRSQLSMSMSYIHDEEEQSKLRKILQEQVLSYEIEIKQVQNELQESKKQFSH 1374

Query: 1337 XXXXXXXXXXXXXXDLRTENQSY--KQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXR 1394
                          +    NQ    K++Q + I N+  +N Q  K              +
Sbjct: 1375 EKESLNKEIQQLKNNAHLLNQQVQEKEIQIKQIENLTTQNIQ--KQYQYENAILKAQIIQ 1432

Query: 1395 VNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYE 1454
            +N+ E    +L  +   K +E    + E  + L Q  D  +     ++  E +++ L  E
Sbjct: 1433 LNE-EISQQKLKCENISKQNE---NSQEINLNLIQLQDSLKEKEILIINLEDQVKQLQLE 1488

Query: 1455 KESEL-AILRLK-MHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKAL 1512
            K     +   LK +H    +   +  + + E++K   ELN +I +  +   Q+ + N+ L
Sbjct: 1489 KNKLFQSSEELKVIHSQQVNQLKLSSQQQCEQLK--NELNTQILDLQNQVNQLLQKNERL 1546

Query: 1513 EEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQ 1555
              + ++  + Q   EN E ++  ++++I   +  ++     I+
Sbjct: 1547 ANQNSEYIQDQQEKENLERQLKEMSEQIEQQEQEIQQQQQLIE 1589



 Score = 96.3 bits (229), Expect = 6e-18
 Identities = 166/872 (19%), Positives = 379/872 (43%), Gaps = 73/872 (8%)

Query: 153  EKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXE 212
            EK+N L   Q+  K  E     L+E++   D I   KN   T                  
Sbjct: 2970 EKENLLQKEQISAKTKEAN--GLREEL---DVINSQKNLEQTESSKQLQEFCQQMETITR 3024

Query: 213  DTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANK-LLEAARFEISLEH 271
            +  Q   ++++  +    + K E+Q++   +ES+  +I   E+  K +LE       +E 
Sbjct: 3025 EKNQIKQELEQFQLDSSNQSKSERQQI-NQLESELAQIKQREQKQKVILEENSKNHKIEK 3083

Query: 272  SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELL 331
             +L Q+++Q                K   +       +IE+  + + A   +L  K + +
Sbjct: 3084 EELQQQIKQVNSVLKAEQENFIQKEKSLNQVIKGHSEQIEQLSNEQKALQNQLNLKNQEI 3143

Query: 332  EHLNCQIR---QTNKELENKLATMGTESKAVSSPS----KKGSPLISRKSGRNTASKMKS 384
              L  Q++   +  ++L  K+  +  +   ++  S    + G  LI      N ++  K 
Sbjct: 3144 AGLILQMKNKEEQQQQLSQKIVQLNQDISNITEQSNIKIQNGEKLIEELQELNNSNHEKL 3203

Query: 385  PWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXG 444
              + L S+   Q    K + +E  K    I+ L  +L  +  V SE +            
Sbjct: 3204 --NDLESKLKAQQQTIKSSASEYQKN---IKQLQDNLQKQTNVNSELEKQNQENLKLIKQ 3258

Query: 445  KDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEK 504
            KD  + ++  + ++         + +  ++  E +++  +  Q+ + E+K + VK  +E 
Sbjct: 3259 KDKQLEEINTQKEK---------MSSQYQEEKEQSQIINKKYQQQDQELKQLLVK--LEN 3307

Query: 505  LKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKV-SDSNKEIVRLTEE 563
             +  E++I      ++     +I  ++  ++K+  +++ I    +  S   KE      E
Sbjct: 3308 YEKQEQEIKNKLINVEEEKSKLIDSQNILEVKVLNLEEHIKRIQEEHSCKTKEFENKQNE 3367

Query: 564  LHH----LSQKVAELEEEKGNLQLHLVDY-DSGRMIESDVYKKMIEMENLAETRLKAISL 618
            L      LS++ A LE+     +L   D  +  +++E +  +K   ++NL E + + IS 
Sbjct: 3368 LLQSNTLLSKQSANLEDVYKQFELKQNDLLNLIQLLEKEKQEKESAIQNLEEIKKQLISQ 3427

Query: 619  LESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASK--- 675
             +  +  L Q    L+ +     +K  D S++Q +++ SE+++  +E+     ++ K   
Sbjct: 3428 NKQNQEKLNQAEADLKNQVQL--NKELDNSKIQLEKMLSELQN-KIEQNTQNANSMKDQL 3484

Query: 676  KELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKL--EKMSAEKIS 733
            K+L + +++             +L++  E+ + K+     +N  ++ +L  EK SA+ + 
Sbjct: 3485 KKLQIQVDDQNKQINSEKAKADELKSTIENQVQKISELQNKNNQISKELNQEKASAQDLK 3544

Query: 734  ELL--AKINHEEQSK--IQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEES----- 784
            E     K+  E+Q K  I T        ++    ++ ++SE+++ K +  +L +      
Sbjct: 3545 EQFNNQKLVLEQQQKENINTSNNFKETNKQLQEQVKLLQSEINQLKQQNDKLNDKHQKEL 3604

Query: 785  ---IAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQL 841
               ++++E+ +  ++ + +Q  +Y QE+ K  S+  IQ ++++++L  L     +  K +
Sbjct: 3605 LTQVSILEELQSKIKSQTEQSSNY-QEQIKQLSDKNIQNEQVIDQL--LCKSKDLETKFI 3661

Query: 842  LEIEHENKEL-----QKKNQILLEENQNLQISLSDMQQHYNALVEKANRTD-LAESESTK 895
            LE E EN++L     +K NQ+ L +++ +   +   +Q  +   E  N  +   ESE  +
Sbjct: 3662 LEQE-ENQKLVNDYEEKMNQLELAKSEEVNSLIEQFKQEKSLWNELKNEENGKIESERNE 3720

Query: 896  YQTQLRDLESNLKRIT-------HEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNE 948
             +T++ +L   +K +         E  T+    K+E++ +++E   QIE   + K  L +
Sbjct: 3721 LKTKMFELFEQVKVLQMVVSDKESEINTIKQSHKEELDQIQLEKQKQIEQLAQQKSNLAQ 3780

Query: 949  KYEKNIEYVTQLEAQLQEYKNNIENLNMNVEE 980
            +  +    + +L+ ++   +++  + +  +E+
Sbjct: 3781 QIFELTNQLQKLQEEIDLNRSSYSHNSSMIED 3812



 Score = 66.1 bits (154), Expect = 8e-09
 Identities = 145/772 (18%), Positives = 324/772 (41%), Gaps = 76/772 (9%)

Query: 837  VEKQLLEIEHENKELQKKNQILLEENQNLQISL---SDMQQHYNALVEKANRTDLAESES 893
            V +Q+    H N  L   +      N+N+ I++   S  QQ+   +    N+ ++++++ 
Sbjct: 224  VTEQIYSFLHRNNALPISSSSTYASNENITIAIQMDSRTQQNSLEVWNDRNQQNISQTDV 283

Query: 894  TKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKN 953
                  +R    NL +I        +Q+ KE    +IE N+++E          E+ +  
Sbjct: 284  FLLMESIRKELDNLIKINKS-----LQQDKE---YQIEENSKLE----------EEIKST 325

Query: 954  IEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINK 1013
            IE  T++  Q++E + +  + N+N   +   +L+++  +  K+        +  + +   
Sbjct: 326  IEIYTKMIEQIKESQEDNFHKNVNQSMILDQSLQVV--YQIKEDNDLKRKVKVLMTDKEA 383

Query: 1014 LNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQL-- 1071
            L   +K  + E        NN     M +  +  S++ + T +++N +E++Q + +Q+  
Sbjct: 384  LQNKIKNLEFE--------NNMMKQTMIVPEEARSQILRATNQIKNGQEQIQELRRQIKQ 435

Query: 1072 LDSKQHNEEL-----QILVREQDDQIKELKETKLTFEMNIPK----TEGMIISSTIEPMS 1122
            L+++   ++L     +  + EQ  + +++  TKL  E+ + K    T+G       +   
Sbjct: 436  LEAQLREQKLNESFSEFRIYEQKYKEEKILTTKLQEEIALLKQGFQTQGATSQILTQKSD 495

Query: 1123 DDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECY----TKIIQL 1178
              +  +             +++    + +  + + ++ S+  N E++       + I ++
Sbjct: 496  MQSRMIGSKKIKGIASQSNIQMPPLSQTLNVQGI-KQSSSNSNQEIESLKKLNDSLIKEI 554

Query: 1179 ETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTV---AELRSSISSAVDQRGFEI 1235
            E L  E   +  V   +IN   SK  Q   +  N L       ++ S + S V Q  F  
Sbjct: 555  ENLKRE-NSNLQVQVSRIN-YDSKSSQNTAQRPNHLQNTKKPIQISSQLQSPVSQFKFGG 612

Query: 1236 AELWKQ----HLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQ 1291
            ++        H A++  D +  +  +    +  E    QL   +Q+ +  +T  I   +Q
Sbjct: 613  SDNANSNSNYHSAEKNLDNKNQQQIINDLQTELEITKNQLKKIMQADSARKT-LITQFDQ 671

Query: 1292 VT--SLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXX 1349
             T  +LQN++  K+  + +LQ++   + N+ +   ++  + +++F               
Sbjct: 672  TTNENLQNQIIQKDITINHLQKQLQMLKNEKDFNPNQ-GNLEMSFLNQSSILEDDLILPT 730

Query: 1350 XDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQL 1409
               +   + Y++ +E+ I+N+  +  QL +S              + D EA   E  + L
Sbjct: 731  SHGQQTFRFYQESKEKEIINLKMQIDQL-QSMNRQKKENIMGLSILEDTEAIKSENAY-L 788

Query: 1410 ELKDSEIYQKTHEYTITLTQRNDEFENVRQ---QLVEYEKRIEDLTYEKESELAILRLKM 1466
            + K  E  QK  +    + Q   E +++ Q   +L++    +     +   EL IL+   
Sbjct: 789  KAK-VESLQKELQNKFNVKQHQAELDSLLQSNKKLIQENSELSQKNRKLMDELDILKNSS 847

Query: 1467 HENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNE-MQTA 1525
            +   +      + +EIE ++   E   KI +   LNKQ+ E+ +  E+ +   N+ M + 
Sbjct: 848  YSKIDLSNAYDRGNEIEELQKKLEKQTKINQ--ILNKQMKEMQENHEQVIDLHNQSMSSI 905

Query: 1526 LENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMN 1577
            L  Q I+      +  +L +++  +   I+++V  A   K+   E+LD+  N
Sbjct: 906  LNPQSIQ------QKNSLASLLATNQKIIEENVQLAQMNKK-LQEELDSIRN 950


>UniRef50_UPI0000D8E0D3 Cluster: UPI0000D8E0D3 related cluster; n=1;
            Danio rerio|Rep: UPI0000D8E0D3 UniRef100 entry - Danio
            rerio
          Length = 2074

 Score =  185 bits (450), Expect = 1e-44
 Identities = 260/1477 (17%), Positives = 649/1477 (43%), Gaps = 91/1477 (6%)

Query: 143  DVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXX 202
            ++T   + IK ++  ++  Q ++  ++T I +LQ+++ ++ +II                
Sbjct: 450  NITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEIIMKDRSQLDLRQSELDK 509

Query: 203  XXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSL-EEANKLLE 261
                     E  K +  ++ ++   ME E K E +++  ++E +   IS + EE     E
Sbjct: 510  QQTNMNDIMETMKNERKQLDKDKEEME-EQKQEMEKMKIELEREADEISKIKEETQNKNE 568

Query: 262  AARFEISLEHSKL-AQELEQXXXXXXXXXXXXXXLAKQSIE--PSCEEKTEIEEKGSLEI 318
              + ++  +H +   +E+                L +  IE     +E  +I+E+   E 
Sbjct: 569  IEKIKLETQHDRQRVEEMAAQIQKKQVFEEEKNKLEQMKIELEREADEIRKIKEETQNER 628

Query: 319  ANMTELTKKIELLEHLNCQIRQTNKELEN-KLATMGTESKA-------VSSPSKKGSPLI 370
             ++ ++T++++  E +  ++ +   E+E  KL T     +        + + + +   L 
Sbjct: 629  QSLEKMTEELKK-EKMKTELEREADEIEKIKLETQHERQRVEEMTADFMETMNNERKQLD 687

Query: 371  SRKSG-RNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKD-----LVDK 424
              K        +M+   S+   +  N+    K+ ++E+ KL+  +Q   K       +DK
Sbjct: 688  KNKVMIEEQKQEMRENISKQIEDIENEKEKSKLREDELKKLQTEVQKQQKRDSESLKLDK 747

Query: 425  EYVISEKDTXXXXXXXXXXGKDTLIA-QLQLEHQQHMEGPSLIHVGTNTEDVNEIAKV-- 481
            E   +EK+             D +   +L+  H++         +    E++N + +   
Sbjct: 748  EAFENEKEAMKQMKTDLQIQADEIEKIKLETHHERQRVEEKTAQIQKEREEINTLVEENQ 807

Query: 482  QEQLKQELNDEIKD-VNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLK---L 537
            QE+ K+ + +  K+   ++++   + + E ++ +L ++I    + M ++K+   ++   L
Sbjct: 808  QEKNKKTITEMQKERETLEEMRANISNRESELAKLQEDILQQQQEMDELKNTIMMEMCQL 867

Query: 538  KQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESD 597
             Q Q  ID      + +KE+  L  +   +  + A+LE  KG LQ+   D +  R ++  
Sbjct: 868  DQRQSDIDLLQNKLNLHKELEELNLQKQGIQDERAQLERMKGELQMKADDIE--RKMQEI 925

Query: 598  VYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLA-----DISQ--L 650
            +Y+K    E  +E   K  + L+    + VQ+L+   ++YDE  +K       DI +   
Sbjct: 926  LYEKQKYAERKSEN-YKIQTYLDEANAE-VQKLNKELERYDENLEKCKLELDKDIRRNLF 983

Query: 651  QSDQVCSEIKSVHLEEQIDA------LSASKKELALVIENLKLDKEQLYGTIKDLENDKE 704
            + ++   + K+  +E + +       L  S++EL   ++ +K +  +L     + +  ++
Sbjct: 984  KKEEAIEKDKAEKIESEREIQQEKKKLQRSEEELEDKMQKIKREMIELKLLQDETDGKRK 1043

Query: 705  DIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSK--IQTQFGIDAKIQERDL 762
            D+ NK++   Q+N ++  + +++ + K+  L  + N  EQ++  ++ Q  I A + ++ L
Sbjct: 1044 DVDNKMR---QQNDEIQKEKQQIESSKML-LSRERNDLEQNRADLERQKQIMA-LDKQKL 1098

Query: 763  YIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDE 822
              EN    L + K+ + ++ E++  + +   + ER  +   +  +E+ +   +   +E E
Sbjct: 1099 LAEN--ELLEREKADVIKIIENLESLREEA-TRERATETAQATKREELEQLKDEINREKE 1155

Query: 823  LVNRLAVLMDH--DRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALV 880
             V     L++   D+   K+  +I+   +ELQ   + LL + ++L    SD+Q     + 
Sbjct: 1156 DVEIRRELVEAVIDKEEMKEFTDIQKYKEELQSVTEELLTKKRDLDQLNSDVQDLRQTIE 1215

Query: 881  EKANRTDLAESESTKYQTQLRDLESN-----LKRITHEHQTLIVQKKKEIEDLEIEFNTQ 935
            ++    +  + +  + +  +  LE        K+   EH T  +QK+++I + + +   Q
Sbjct: 1216 KEKEELEQLKKDINREKEDIETLEEVDIQYIKKKAELEHITSEIQKREQILEKQKKNKNQ 1275

Query: 936  IESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELID-KHVQ 994
            IE   +D + +    E+ +E +   +A ++E +  +++L M + ++ +   E+ D K + 
Sbjct: 1276 IEQEKKDLQNMKSNLERQLESLRHEKANVEEIELKVKDLEMEMADMKRQKQEIEDTKGLL 1335

Query: 995  KQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFT 1054
            +++ Q     ++ + +  ++  L ++K E      ++  N  ++  + + D     ++  
Sbjct: 1336 EKEKQELKQEKKELED--QMMDLTREKQE-----TEEERNNLMALKNQLEDLRKIKSELV 1388

Query: 1055 TKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMII 1114
             +   ++ E ++++  +   +Q  E+L+ +  E   Q +E+++ +     N    E   +
Sbjct: 1389 REKTEVDHEQKKLNDDIKMIEQEKEDLEKMKSEIMTQKQEMEKERKEERRN---EETRRL 1445

Query: 1115 SSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTK 1174
               +E MS D N  +             + + + +  + RS +  +  KLN + +    +
Sbjct: 1446 KEDLEKMSTDVNKQNKDLMNQRDLLEQEREEIKSQLERVRSEIDHEQKKLNDDKKMIEQE 1505

Query: 1175 IIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTEN----------DNLLSTVAELRSSI 1224
               LE + +E+       +E+ ++L +K++Q + E             L+  V E R  I
Sbjct: 1506 KEDLEKMKSEIMKQRQQMEEERSELDNKIKQTDLERHDIENSKEIVQKLMVEVEEQRKDI 1565

Query: 1225 SSAVDQRGFEIAELWKQH--LAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEE 1282
                ++   E  ++  +   + Q +A  Q  E+E   ++     K ++ L  +++  ++E
Sbjct: 1566 RLQKEELDIERQKIADEQGLVVQNKAKLQ-NENERIKEMDEEIKKEKETLKEMEAHLRKE 1624

Query: 1283 TNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXX 1342
              ++ ++ + T  + K +D E+   ++ ++  D++NQ ++L+ E E+    F        
Sbjct: 1625 KEEMRSVIEETQRRQK-EDLEKMSTDVNKQNQDLMNQRDLLKQEREERIDEFDAQVSKQK 1683

Query: 1343 XXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKV 1402
                     +  E +  ++M+ + I+   ++  + +                + + EA +
Sbjct: 1684 EEDLTKQKKMEEEKEDLEKMKSE-IMKQRQQMEEERSELENKNEVIKKERETLKEMEAYL 1742

Query: 1403 LELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAIL 1462
             +   +++    E  ++  +     T  N++ +++R Q    E+  E++ + K  +L   
Sbjct: 1743 EKEKEEMKSITEETRRQKEDLEKMSTHINEQKQDLRSQRDLLEQEREEINH-KWKQLQQR 1801

Query: 1463 RLKMHENANHYETMQKESEIERVKLIEELNVKI---TESVSLNKQVAELNKALEEEVAKT 1519
              +           ++E +IER K+ +E ++ I    E  + N+++ E+++ +++E    
Sbjct: 1802 IDEFDAQIKSQLERKEELDIERQKIADEQDLLIQNKIEQQNENERIKEMDEEIKKERETL 1861

Query: 1520 NEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQK 1556
             EM+  L+ ++ EI ++ +E    +  +   S+ I +
Sbjct: 1862 KEMEVNLQKEKEEIESVIEETQRRKEDLEKMSTDINE 1898



 Score =  163 bits (395), Expect = 5e-38
 Identities = 280/1475 (18%), Positives = 617/1475 (41%), Gaps = 117/1475 (7%)

Query: 147  LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXX 206
            LS   K K+  L  ++V     E+T+ D+  + +   ++ E  +K T             
Sbjct: 114  LSEDAKRKNQVLDEMKVAN---ESTLADILRERSNLQEMRENISKQTEDVENKKEKIRLR 170

Query: 207  XXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFE 266
                 +  + ++ K Q      ++  + E+  ++KD+E    +I SL+   + L+  R  
Sbjct: 171  EEKLKQ-LQAEIHKQQSETEKEKSNIERERAAIIKDVEDLQSKIISLDRDAESLKLDREA 229

Query: 267  ISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTK 326
               E  +L Q   +              L K   E   E+K E+E++      +   L K
Sbjct: 230  FENEKEELKQMKTELEREAETMNNERKQLNKNKEEMQ-EQKQEMEKERHDMDQSRKSLDK 288

Query: 327  KIELLEHLNCQIRQT---NKELENKLATMGTESKAVSSPSKKGSPLISRKS---GRNTAS 380
             +++++    + R      KE   K      E + + +   K    I ++        A+
Sbjct: 289  NLKMMKLQKQKTRSKLLRAKENLEKQRLREDELRQLQAEIHKQQREIEKEKINIESERAA 348

Query: 381  KMKSPWS-QLSSETLNQDTDK-KINKNEIAKLEMVIQSLNKDLVDK-EYVISEKDTXXXX 437
             +K     Q     L++D +  K+++ E  + +MV+   N+D+ +K + + S+KD     
Sbjct: 349  IIKDVEDLQHKIICLDRDAESLKLDREETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKE 408

Query: 438  XXXXXXGKDTLI-AQLQLEHQQ-------HMEGPSLIHVGTN-TEDVNEIAKVQEQL--K 486
                   +  L   +  LE Q+         E   L  +  N T +++EI   +EQ+  K
Sbjct: 409  KHDLEKTRSELYKVKEDLEKQKENTLAEIQKEREDLEKMNENITREMHEIKHQEEQMNQK 468

Query: 487  QELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDN 546
            Q+  D++K   +++L ++L+  +E I +   ++D     + K ++N    +  + +T+ N
Sbjct: 469  QDELDQLK-TEIQNLQQELEKEKEIIMKDRSQLDLRQSELDKQQTN----MNDIMETMKN 523

Query: 547  FSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEME 606
              K  D +KE   + E+   + +   ELE E   +     +  +   IE    +   + +
Sbjct: 524  ERKQLDKDKE--EMEEQKQEMEKMKIELEREADEISKIKEETQNKNEIEKIKLETQHDRQ 581

Query: 607  NLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEE 666
             + E    A  + + Q F+  +E + L+Q   E+E +  +I +++ ++  +E +S  LE+
Sbjct: 582  RVEE---MAAQIQKKQVFE--EEKNKLEQMKIELEREADEIRKIK-EETQNERQS--LEK 633

Query: 667  QIDALSASKKELAL-----VIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLT 721
              + L   K +  L      IE +KL+ +     ++++  D  + MN  +  + +N  + 
Sbjct: 634  MTEELKKEKMKTELEREADEIEKIKLETQHERQRVEEMTADFMETMNNERKQLDKNKVMI 693

Query: 722  DKLEKMSAEKISELL---------AKINHEEQSKIQTQFGIDAKIQERDLYIENIESELS 772
            ++ ++   E IS+ +         +K+  +E  K+QT+     K     L ++    E  
Sbjct: 694  EEQKQEMRENISKQIEDIENEKEKSKLREDELKKLQTEVQKQQKRDSESLKLDKEAFENE 753

Query: 773  KYKSRICRLEESIAVMEDRRYSLE-----RKADQLGSYLQEKQKAYSEYTIQEDELVNRL 827
            K   +  + +  I   E  +  LE     ++ ++  + +Q++++  +    +  +  N+ 
Sbjct: 754  KEAMKQMKTDLQIQADEIEKIKLETHHERQRVEEKTAQIQKEREEINTLVEENQQEKNKK 813

Query: 828  AVL-MDHDR-VVEKQLLEIEHENKELQKKNQILLEENQ-------NLQISLSDMQQHYNA 878
             +  M  +R  +E+    I +   EL K  + +L++ Q        + + +  + Q  + 
Sbjct: 814  TITEMQKERETLEEMRANISNRESELAKLQEDILQQQQEMDELKNTIMMEMCQLDQRQSD 873

Query: 879  LVEKANRTDL-AESESTKYQTQ-LRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQI 936
            +    N+ +L  E E    Q Q ++D  + L+R+  E Q      +++++++  E     
Sbjct: 874  IDLLQNKLNLHKELEELNLQKQGIQDERAQLERMKGELQMKADDIERKMQEILYEKQKYA 933

Query: 937  ESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQ 996
            E    + K+     E N E V +L  +L+ Y  N+E   + +++  + NL   ++ ++K 
Sbjct: 934  ERKSENYKIQTYLDEANAE-VQKLNKELERYDENLEKCKLELDKDIRRNLFKKEEAIEKD 992

Query: 997  QTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTK 1056
            + +  + +E+   EI +    L++ +EE+    QKI    +    +  + + K      K
Sbjct: 993  KAEKIE-SER---EIQQEKKKLQRSEEELEDKMQKIKREMIELKLLQDETDGKRKDVDNK 1048

Query: 1057 LENMEEEMQR------VSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTE 1110
            +    +E+Q+       SK LL  ++++ E      E+  QI  L + KL  E  + + E
Sbjct: 1049 MRQQNDEIQKEKQQIESSKMLLSRERNDLEQNRADLERQKQIMALDKQKLLAENELLERE 1108

Query: 1111 GMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQE 1170
               +   IE +  ++   +             K +EE E +++    +++  ++  EL E
Sbjct: 1109 KADVIKIIENL--ESLREEATRERATETAQATK-REELEQLKDEINREKEDVEIRRELVE 1165

Query: 1171 CYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTEN---DNLLSTVAELRSSISSA 1227
                +I  E +  E T  D+  Q+   +L+S  E+L T+    D L S V +LR +I   
Sbjct: 1166 A---VIDKEEMK-EFT--DI--QKYKEELQSVTEELLTKKRDLDQLNSDVQDLRQTIEKE 1217

Query: 1228 VDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQ----EET 1283
             +    E+ +L K     RE +  +T  E+ +Q    +++ E +   +Q   Q    ++ 
Sbjct: 1218 KE----ELEQLKKD--INREKEDIETLEEVDIQYIKKKAELEHITSEIQKREQILEKQKK 1271

Query: 1284 NKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXX 1343
            NK    ++   LQN   + E  L +L+ + A+V  +IE+   ++E E             
Sbjct: 1272 NKNQIEQEKKDLQNMKSNLERQLESLRHEKANV-EEIELKVKDLEMEMADMKRQKQEIED 1330

Query: 1344 XXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVL 1403
                   + +   Q  K++++Q ++++  E    K+ +            ++ D      
Sbjct: 1331 TKGLLEKEKQELKQEKKELEDQ-MMDLTRE----KQETEEERNNLMALKNQLEDLRKIKS 1385

Query: 1404 ELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILR 1463
            EL  +    D E  +K ++    + Q  ++ E ++ +++  ++ +E    E+       R
Sbjct: 1386 ELVREKTEVDHE-QKKLNDDIKMIEQEKEDLEKMKSEIMTQKQEMEKERKEERRNEETRR 1444

Query: 1464 LKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQ 1523
            LK        E M  +   +   L+ + ++   E   +  Q+  +   ++ E  K N+ +
Sbjct: 1445 LK-----EDLEKMSTDVNKQNKDLMNQRDLLEQEREEIKSQLERVRSEIDHEQKKLNDDK 1499

Query: 1524 TALENQEIEIVTLNDEITNLQNMVRASSSKIQKHV 1558
              +E ++ ++  +  EI   +  +    S++   +
Sbjct: 1500 KMIEQEKEDLEKMKSEIMKQRQQMEEERSELDNKI 1534



 Score =  159 bits (387), Expect = 4e-37
 Identities = 243/1181 (20%), Positives = 534/1181 (45%), Gaps = 116/1181 (9%)

Query: 220  KMQENFIAME--AEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQE 277
            KMQE     +  AE K E  ++   ++  +  +  L   NK LE  R++ +LE  KL  E
Sbjct: 921  KMQEILYEKQKYAERKSENYKIQTYLDEANAEVQKL---NKELE--RYDENLEKCKL--E 973

Query: 278  LEQXXXXXXXXXXXXXXLAK-QSIEPSCE---EKTEIEEKGSLEIANMTELTKKIELLEH 333
            L++                K + IE   E   EK +++         M ++ +++  L+ 
Sbjct: 974  LDKDIRRNLFKKEEAIEKDKAEKIESEREIQQEKKKLQRSEEELEDKMQKIKREMIELKL 1033

Query: 334  LNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSET 393
            L  +     K+++NK+     E +      +    L+SR+  RN   + ++   +   + 
Sbjct: 1034 LQDETDGKRKDVDNKMRQQNDEIQKEKQQIESSKMLLSRE--RNDLEQNRADLER-QKQI 1090

Query: 394  LNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQ 453
            +  D  K + +NE+ + E     + K +++    + E+ T           K   + QL+
Sbjct: 1091 MALDKQKLLAENELLEREKA--DVIK-IIENLESLREEATRERATETAQATKREELEQLK 1147

Query: 454  LEHQQHMEGPS----LIHVGTNTEDVNE---IAKVQEQLK---QELNDEIKDVN-----V 498
             E  +  E       L+    + E++ E   I K +E+L+   +EL  + +D++     V
Sbjct: 1148 DEINREKEDVEIRRELVEAVIDKEEMKEFTDIQKYKEELQSVTEELLTKKRDLDQLNSDV 1207

Query: 499  KDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIV 558
            +DL + ++  +E++ QL  +I+   +++  ++      +K+  +     S++    + + 
Sbjct: 1208 QDLRQTIEKEKEELEQLKKDINREKEDIETLEEVDIQYIKKKAELEHITSEIQKREQILE 1267

Query: 559  RLTEELHHLSQKVAELEEEKGNL--QLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAI 616
            +  +  + + Q+  +L+  K NL  QL  + ++   + E ++  K +EME     R K  
Sbjct: 1268 KQKKNKNQIEQEKKDLQNMKSNLERQLESLRHEKANVEEIELKVKDLEMEMADMKRQK-- 1325

Query: 617  SLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKK 676
              +E  K  L +E   L+Q+  E+ED++ D+++ + +        + L+ Q++ L   K 
Sbjct: 1326 QEIEDTKGLLEKEKQELKQEKKELEDQMMDLTREKQETEEERNNLMALKNQLEDLRKIKS 1385

Query: 677  ELALVIENLKLDKEQ--LYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISE 734
            EL  V E  ++D EQ  L   IK +E +KED+  K+++ I       +K  K   E+ +E
Sbjct: 1386 EL--VREKTEVDHEQKKLNDDIKMIEQEKEDL-EKMKSEIMTQKQEMEKERK--EERRNE 1440

Query: 735  LLAKINHEEQSKIQTQFGIDAK--IQERDLYI---ENIESELSKYKSRICRLEESIAVME 789
               ++  E+  K+ T      K  + +RDL     E I+S+L + +S I   ++ +    
Sbjct: 1441 ETRRLK-EDLEKMSTDVNKQNKDLMNQRDLLEQEREEIKSQLERVRSEIDHEQKKL---N 1496

Query: 790  DRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAV--LMDHD-----RVVEKQLL 842
            D +  +E++ + L     E  K   +   +  EL N++    L  HD      +V+K ++
Sbjct: 1497 DDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDNKIKQTDLERHDIENSKEIVQKLMV 1556

Query: 843  EIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRD 902
            E+E + K+++ + + L  E Q +      + Q+   L  +  R    + E  K +  L++
Sbjct: 1557 EVEEQRKDIRLQKEELDIERQKIADEQGLVVQNKAKLQNENERIKEMDEEIKKEKETLKE 1616

Query: 903  LESNLKRITHEHQTLIVQ----KKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNI-EYV 957
            +E++L++   E +++I +    +K+++E +  + N Q +  +  + +L ++ E+ I E+ 
Sbjct: 1617 MEAHLRKEKEEMRSVIEETQRRQKEDLEKMSTDVNKQNQDLMNQRDLLKQEREERIDEFD 1676

Query: 958  TQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSP-----DYTEQYINEIN 1012
             Q+  Q +E     + +    E+L KM  E++ +  Q ++ +S      +  ++    + 
Sbjct: 1677 AQVSKQKEEDLTKQKKMEEEKEDLEKMKSEIMKQRQQMEEERSELENKNEVIKKERETLK 1736

Query: 1013 KLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLL 1072
            ++ A L+++ EE+ ++ ++    +     M +    +     ++ + +E+E + ++ +  
Sbjct: 1737 EMEAYLEKEKEEMKSITEETRRQKEDLEKMSTHINEQKQDLRSQRDLLEQEREEINHKWK 1796

Query: 1073 DSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXX 1132
              +Q  +E    ++ Q ++ +EL   +      I   + ++I + IE  +++        
Sbjct: 1797 QLQQRIDEFDAQIKSQLERKEELDIER----QKIADEQDLLIQNKIEQQNENER------ 1846

Query: 1133 XXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQ-------LETLNTEL 1185
                     +K + +EE  +ER  L+E    L  E +E  + I +       LE ++T++
Sbjct: 1847 ---------IK-EMDEEIKKERETLKEMEVNLQKEKEEIESVIEETQRRKEDLEKMSTDI 1896

Query: 1186 T--GHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVD---QRGFEIAELWK 1240
                 D++NQ  +  LK + E++N +   L   + E  ++ +  V    +   E+ E  +
Sbjct: 1897 NEQKQDLMNQRDL--LKQEREEMNHKLTQLQQRIDEFETTSNILVTTKMEEKTEMDEKLQ 1954

Query: 1241 QHLAQREADFQKTEHELRVQLSAFESKYEQL-LDSVQSSTQEETNK------IVTMEQVT 1293
            Q + + E+  ++T  + R +L   E + +    +   S    ET K       + +++V 
Sbjct: 1955 QAIKEYESIIEETNRK-RTELEEIEKERKDTEKERGCSRGGTETGKKGGEFERIQIDEVK 2013

Query: 1294 SLQNKL-QDKEEHLRNLQ--EKYADVINQIEILRSEIEDEK 1331
             + +++ ++K+E  RN Q  E   + + +I+  R EIE  K
Sbjct: 2014 RILSEIHKEKKELERNKQILEHQREALLEIKKEREEIEKMK 2054



 Score =  155 bits (376), Expect = 1e-35
 Identities = 284/1516 (18%), Positives = 644/1516 (42%), Gaps = 148/1516 (9%)

Query: 151  IKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXX 210
            I+E+ + L  ++++++     I  ++E+   + QI E   +A                  
Sbjct: 65   IEEEKSKLKQMKIELEREADEIRKVKEETQNERQIFEKMTEALKKEREDLSEDAKRKNQV 124

Query: 211  XEDTKQQMTKMQENFIAMEAEWKDEKQRLLK---DIESKDVRISSLEEANKLLEAA--RF 265
             ++ K        + +   +  ++ ++ + K   D+E+K  +I   EE  K L+A   + 
Sbjct: 125  LDEMKVANESTLADILRERSNLQEMRENISKQTEDVENKKEKIRLREEKLKQLQAEIHKQ 184

Query: 266  EISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANM-TEL 324
            +   E  K   E E+              ++      S +   E  E    E+  M TEL
Sbjct: 185  QSETEKEKSNIERERAAIIKDVEDLQSKIISLDRDAESLKLDREAFENEKEELKQMKTEL 244

Query: 325  TKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLIS--RKSGRNTASKM 382
             ++ E + +   Q+ +  +E++ +   M  E   +    K     +   +   + T SK+
Sbjct: 245  EREAETMNNERKQLNKNKEEMQEQKQEMEKERHDMDQSRKSLDKNLKMMKLQKQKTRSKL 304

Query: 383  KSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXX 442
                  L  + L +D  +++   EI K +  I+   K  ++ E     KD          
Sbjct: 305  LRAKENLEKQRLREDELRQLQA-EIHKQQREIEK-EKINIESERAAIIKDVEDLQHKIIC 362

Query: 443  XGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNV-KDL 501
              +D     L+L+ ++           TN +D+     V  +  +++ ++IK +   KD+
Sbjct: 363  LDRDA--ESLKLDREE-----------TNRKDM-----VLNEKNRDIEEKIKSIQSDKDM 404

Query: 502  IEK----LKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDN-FSKVSDSNKE 556
            +EK    L+    ++ ++ ++++   +N +      +  L++M + I     ++    ++
Sbjct: 405  LEKEKHDLEKTRSELYKVKEDLEKQKENTLAEIQKEREDLEKMNENITREMHEIKHQEEQ 464

Query: 557  IVRLTEELHHLSQKVAELEEE-KGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKA 615
            + +  +EL  L  ++  L++E +   ++ + D     + +S++ K+   M ++ ET    
Sbjct: 465  MNQKQDELDQLKTEIQNLQQELEKEKEIIMKDRSQLDLRQSELDKQQTNMNDIMETMKNE 524

Query: 616  ISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSD-QVCSEIKSVHLEEQID----- 669
               L+  K ++ ++   +++   E+E +  +IS+++ + Q  +EI+ + LE Q D     
Sbjct: 525  RKQLDKDKEEMEEQKQEMEKMKIELEREADEISKIKEETQNKNEIEKIKLETQHDRQRVE 584

Query: 670  --ALSASKKEL----ALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDK 723
              A    KK++       +E +K++ E+    I+ ++ + ++    L+   +E      K
Sbjct: 585  EMAAQIQKKQVFEEEKNKLEQMKIELEREADEIRKIKEETQNERQSLEKMTEELKKEKMK 644

Query: 724  LE-KMSAEKISELLAKINHEEQS-KIQTQFGIDAKIQERDLYIEN---IESELSKYKSRI 778
             E +  A++I ++  +  HE Q  +  T   ++    ER    +N   IE +  + +  I
Sbjct: 645  TELEREADEIEKIKLETQHERQRVEEMTADFMETMNNERKQLDKNKVMIEEQKQEMRENI 704

Query: 779  CRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRV-- 836
             +  E I   +++    E +  +L + +Q++QK  SE    + E        M   +   
Sbjct: 705  SKQIEDIENEKEKSKLREDELKKLQTEVQKQQKRDSESLKLDKEAFENEKEAMKQMKTDL 764

Query: 837  ------VEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAE 890
                  +EK  LE  HE + +++K   + +E + +   + + QQ  N    K   T++ +
Sbjct: 765  QIQADEIEKIKLETHHERQRVEEKTAQIQKEREEINTLVEENQQEKN----KKTITEMQK 820

Query: 891  SEST--KYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNT---QIESAIRDKKV 945
               T  + +  + + ES L ++  +    I+Q+++E+++L+        Q++    D  +
Sbjct: 821  ERETLEEMRANISNRESELAKLQED----ILQQQQEMDELKNTIMMEMCQLDQRQSDIDL 876

Query: 946  LNEKYE--KNIEYVTQLEAQLQEYKNNIEN----LNMNVEELNKMNLELIDKHVQKQQTQ 999
            L  K    K +E +   +  +Q+ +  +E     L M  +++ +   E++ +  +  + +
Sbjct: 877  LQNKLNLHKELEELNLQKQGIQDERAQLERMKGELQMKADDIERKMQEILYEKQKYAERK 936

Query: 1000 SPDYTEQ-YINEIN----KLNALLKQKDEEI----IALNQKINNAQVSYMSMVSDYESKL 1050
            S +Y  Q Y++E N    KLN  L++ DE +    + L++ I          +   +++ 
Sbjct: 937  SENYKIQTYLDEANAEVQKLNKELERYDENLEKCKLELDKDIRRNLFKKEEAIEKDKAEK 996

Query: 1051 AQFTTKLENMEEEMQRVSKQLLDSKQHNE----ELQILVREQDDQIKELKETKLTFEMNI 1106
             +   +++  ++++QR  ++L D  Q  +    EL++L  E D + K++ + K+  + + 
Sbjct: 997  IESEREIQQEKKKLQRSEEELEDKMQKIKREMIELKLLQDETDGKRKDV-DNKMRQQNDE 1055

Query: 1107 PKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNT 1166
             + E   I S+   +S + N+++            + + ++++ + E  +L+ + A +  
Sbjct: 1056 IQKEKQQIESSKMLLSRERNDLEQNRADLERQKQIMAL-DKQKLLAENELLEREKADV-- 1112

Query: 1167 ELQECYTKIIQ-LETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSIS 1225
                   KII+ LE+L  E T        Q  + + +LEQL  E +     V   R  + 
Sbjct: 1113 ------IKIIENLESLREEATRERATETAQATK-REELEQLKDEINREKEDVEIRRELVE 1165

Query: 1226 SAVDQRGF-EIAELWK---------QHLAQREADFQKTEHELRVQLSAFESKYEQLLDSV 1275
            + +D+    E  ++ K         + L  ++ D  +   +++      E + E+L + +
Sbjct: 1166 AVIDKEEMKEFTDIQKYKEELQSVTEELLTKKRDLDQLNSDVQDLRQTIEKEKEEL-EQL 1224

Query: 1276 QSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFX 1335
            +     E   I T+E+V     K + + EH+ +  +K   ++ + +  +++IE EK    
Sbjct: 1225 KKDINREKEDIETLEEVDIQYIKKKAELEHITSEIQKREQILEKQKKNKNQIEQEK---- 1280

Query: 1336 XXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRV 1395
                            LR E  + +++ E  + ++  E A +K+               +
Sbjct: 1281 KDLQNMKSNLERQLESLRHEKANVEEI-ELKVKDLEMEMADMKRQKQ-----------EI 1328

Query: 1396 NDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEK 1455
             D +  +LE   Q ELK  +  ++  +  + LT+   E E  R  L+  + ++EDL   K
Sbjct: 1329 EDTKG-LLEKEKQ-ELKQEK--KELEDQMMDLTREKQETEEERNNLMALKNQLEDLRKIK 1384

Query: 1456 ESELAILRLKM-HENANHYETM----QKESEIERVK---LIEELNV-KITESVSLNKQVA 1506
             SEL   + ++ HE     + +    Q++ ++E++K   + ++  + K  +    N++  
Sbjct: 1385 -SELVREKTEVDHEQKKLNDDIKMIEQEKEDLEKMKSEIMTQKQEMEKERKEERRNEETR 1443

Query: 1507 ELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQ 1566
             L + LE+     N+    L NQ   +    +EI +    VR+     QK ++   D K 
Sbjct: 1444 RLKEDLEKMSTDVNKQNKDLMNQRDLLEQEREEIKSQLERVRSEIDHEQKKLN--DDKKM 1501

Query: 1567 GRDEQLD-NTMNKELL 1581
               E+ D   M  E++
Sbjct: 1502 IEQEKEDLEKMKSEIM 1517



 Score =  143 bits (347), Expect = 3e-32
 Identities = 245/1387 (17%), Positives = 580/1387 (41%), Gaps = 80/1387 (5%)

Query: 145  THLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXX 204
            T L     E +      Q + + +E    D  E +N + + ++ KNK             
Sbjct: 645  TELEREADEIEKIKLETQHERQRVEEMTADFMETMNNERKQLD-KNKVMIEEQKQEMREN 703

Query: 205  XXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAAR 264
                    + +++ +K++E+ +  + + + +KQ+  +D ES  +   + E   + ++  +
Sbjct: 704  ISKQIEDIENEKEKSKLREDELK-KLQTEVQKQQK-RDSESLKLDKEAFENEKEAMKQMK 761

Query: 265  FEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTEL 324
             ++ ++  ++ +   +              + K+  E +   +   +EK    I   TE+
Sbjct: 762  TDLQIQADEIEKIKLETHHERQRVEEKTAQIQKEREEINTLVEENQQEKNKKTI---TEM 818

Query: 325  TKKIELLEHLNCQIRQTNKEL----ENKLATMGTESKAVSSPSKKGSPLISRKSGRNTAS 380
             K+ E LE +   I     EL    E+ L       +  ++   +   L  R+S  +   
Sbjct: 819  QKERETLEEMRANISNRESELAKLQEDILQQQQEMDELKNTIMMEMCQLDQRQSDIDLLQ 878

Query: 381  KMKSPWSQLSSETLN----QDTDKKIN--KNEIAKLEMVIQSLNKDLVDKEYVISEKDTX 434
               +   +L    L     QD   ++   K E+      I+   ++++ ++   +E+ + 
Sbjct: 879  NKLNLHKELEELNLQKQGIQDERAQLERMKGELQMKADDIERKMQEILYEKQKYAERKSE 938

Query: 435  XXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIK 494
                       +  + +L  E +++ E      +  + +    + K +E ++++  ++I+
Sbjct: 939  NYKIQTYLDEANAEVQKLNKELERYDENLEKCKLELDKDIRRNLFKKEEAIEKDKAEKIE 998

Query: 495  DVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSN 554
              + +++ ++ K  +    +L D++    + MI++K     +    +K +DN  K+   N
Sbjct: 999  --SEREIQQEKKKLQRSEEELEDKMQKIKREMIELKLLQD-ETDGKRKDVDN--KMRQQN 1053

Query: 555  KEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIES-DVYKKMIEMENLAETRL 613
             EI +  +++   S K+  L  E+ +L+ +  D +  + I + D  K + E E L   + 
Sbjct: 1054 DEIQKEKQQIE--SSKML-LSRERNDLEQNRADLERQKQIMALDKQKLLAENELLEREKA 1110

Query: 614  KAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSA 673
              I ++E+ +  L +E    +        K  ++ QL+ D++  E + V +  ++     
Sbjct: 1111 DVIKIIENLE-SLREEATRERATETAQATKREELEQLK-DEINREKEDVEIRRELVEAVI 1168

Query: 674  SKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKIS 733
             K+E+    +  K  KE+L    ++L   K D+ ++L + +Q   DL   +EK   E++ 
Sbjct: 1169 DKEEMKEFTDIQKY-KEELQSVTEELLTKKRDL-DQLNSDVQ---DLRQTIEK-EKEELE 1222

Query: 734  ELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRY 793
            +L   IN E++  I+T   +D +  ++   +E+I SE+ K +  + + +++   +E  + 
Sbjct: 1223 QLKKDINREKED-IETLEEVDIQYIKKKAELEHITSEIQKREQILEKQKKNKNQIEQEKK 1281

Query: 794  SLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQK 853
             L+     L   L+  +  + +  ++E EL  +   +   D   +KQ  EIE     L+K
Sbjct: 1282 DLQNMKSNLERQLESLR--HEKANVEEIELKVKDLEMEMADMKRQKQ--EIEDTKGLLEK 1337

Query: 854  KNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHE 913
            + Q L +E + L+  + D+ +      E+ N     +++    +    +L      + HE
Sbjct: 1338 EKQELKQEKKELEDQMMDLTREKQETEEERNNLMALKNQLEDLRKIKSELVREKTEVDHE 1397

Query: 914  HQTL------IVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEY 967
             + L      I Q+K+++E ++ E  TQ +   +++K      E+  E   +L+  L++ 
Sbjct: 1398 QKKLNDDIKMIEQEKEDLEKMKSEIMTQKQEMEKERKE-----ERRNEETRRLKEDLEKM 1452

Query: 968  KNNIENLN---MNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEE 1024
              ++   N   MN  +L +   E I   +++ +++  D+ ++ +N+  K+   ++Q+ E+
Sbjct: 1453 STDVNKQNKDLMNQRDLLEQEREEIKSQLERVRSEI-DHEQKKLNDDKKM---IEQEKED 1508

Query: 1025 IIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQIL 1084
            +  +  +I   +       S+ ++K+ Q   +  ++E   + V K +++ ++  +++++ 
Sbjct: 1509 LEKMKSEIMKQRQQMEEERSELDNKIKQTDLERHDIENSKEIVQKLMVEVEEQRKDIRLQ 1568

Query: 1085 VREQDDQIKELKETKLTFEMNIPK--TEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXL 1142
              E D + +++ + +     N  K   E   I    E +  +   +             +
Sbjct: 1569 KEELDIERQKIADEQGLVVQNKAKLQNENERIKEMDEEIKKEKETLKEMEAHLRKEKEEM 1628

Query: 1143 KVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTE-LTGHDVVNQEQINQLKS 1201
            +   EE   +++  L++ S  +N + Q+   +   L+    E +   D    +Q  +  +
Sbjct: 1629 RSVIEETQRRQKEDLEKMSTDVNKQNQDLMNQRDLLKQEREERIDEFDAQVSKQKEEDLT 1688

Query: 1202 KLEQLNTENDNLLSTVAELRSSISSAVDQRGF-----EIAELWKQHLAQREADFQKTEHE 1256
            K +++  E ++L    +E+        ++R       E+ +  ++ L + EA  +K + E
Sbjct: 1689 KQKKMEEEKEDLEKMKSEIMKQRQQMEEERSELENKNEVIKKERETLKEMEAYLEKEKEE 1748

Query: 1257 LRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADV 1316
            ++   S  E    Q  D  + ST     K     Q   L+ + ++     + LQ++  + 
Sbjct: 1749 MK---SITEETRRQKEDLEKMSTHINEQKQDLRSQRDLLEQEREEINHKWKQLQQRIDEF 1805

Query: 1317 INQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQ---SILNINEE 1373
              QI+  + E ++E                    + + EN+  K+M E+       + E 
Sbjct: 1806 DAQIKS-QLERKEELDIERQKIADEQDLLIQNKIEQQNENERIKEMDEEIKKERETLKEM 1864

Query: 1374 NAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLE--LKDSEIYQKTHEYTITLTQRN 1431
               L+K              R  D E    ++  Q +  +   ++ ++  E      + N
Sbjct: 1865 EVNLQKEKEEIESVIEETQRRKEDLEKMSTDINEQKQDLMNQRDLLKQERE------EMN 1918

Query: 1432 DEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIE-E 1490
             +   ++Q++ E+E     L   K  E   +  K+ +    YE++ +E+  +R +L E E
Sbjct: 1919 HKLTQLQQRIDEFETTSNILVTTKMEEKTEMDEKLQQAIKEYESIIEETNRKRTELEEIE 1978

Query: 1491 LNVKITE 1497
               K TE
Sbjct: 1979 KERKDTE 1985



 Score =  138 bits (334), Expect = 1e-30
 Identities = 216/1172 (18%), Positives = 499/1172 (42%), Gaps = 93/1172 (7%)

Query: 473  EDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSN 532
            ED++E AK + Q+  E+     +  + D++ +  + +E    ++ + +       K++  
Sbjct: 112  EDLSEDAKRKNQVLDEMK-VANESTLADILRERSNLQEMRENISKQTEDVENKKEKIRLR 170

Query: 533  HKLKLKQMQKTI-----DNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVD 587
             + KLKQ+Q  I     +   + S+  +E   + +++  L  K+  L+ +  +L+L    
Sbjct: 171  EE-KLKQLQAEIHKQQSETEKEKSNIERERAAIIKDVEDLQSKIISLDRDAESLKLDREA 229

Query: 588  YDSGR----MIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDK 643
            +++ +     +++++ ++   M N  +   K    ++ QK ++ +E H + Q    + DK
Sbjct: 230  FENEKEELKQMKTELEREAETMNNERKQLNKNKEEMQEQKQEMEKERHDMDQSRKSL-DK 288

Query: 644  LADISQLQSDQVCSEIKSV--HLEEQI---DALSASKKELALVIENLKLDKEQLYGTIKD 698
               + +LQ  +  S++     +LE+Q    D L   + E+      ++ +K  +      
Sbjct: 289  NLKMMKLQKQKTRSKLLRAKENLEKQRLREDELRQLQAEIHKQQREIEKEKINIESERAA 348

Query: 699  LENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQ 758
            +  D ED+ +K+    ++   L  KL++    +   +L + N + + KI++    D  + 
Sbjct: 349  IIKDVEDLQHKIICLDRDAESL--KLDREETNRKDMVLNEKNRDIEEKIKS-IQSDKDML 405

Query: 759  ERDLY-IENIESELSKYKSRICRLEES-IAVMEDRRYSLERKADQLGSYLQEKQKAYSEY 816
            E++ + +E   SEL K K  + + +E+ +A ++  R  LE+  + +   + E +    + 
Sbjct: 406  EKEKHDLEKTRSELYKVKEDLEKQKENTLAEIQKEREDLEKMNENITREMHEIKHQEEQM 465

Query: 817  TIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHY 876
              ++DEL      + +  + +EK+   I  +  +L  +   L ++  N+   +  M+   
Sbjct: 466  NQKQDELDQLKTEIQNLQQELEKEKEIIMKDRSQLDLRQSELDKQQTNMNDIMETMKNER 525

Query: 877  NALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFN--- 933
              L +     +  + E  K + +L      + +I  E      Q K EIE +++E     
Sbjct: 526  KQLDKDKEEMEEQKQEMEKMKIELEREADEISKIKEE-----TQNKNEIEKIKLETQHDR 580

Query: 934  ---TQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELID 990
                ++ + I+ K+V  E+  K  +   +LE +  E +   E      + L KM  EL  
Sbjct: 581  QRVEEMAAQIQKKQVFEEEKNKLEQMKIELEREADEIRKIKEETQNERQSLEKMTEEL-- 638

Query: 991  KHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKL 1050
               +K +T+     E+  +EI K+   L+ + E      Q++      +M  +++   +L
Sbjct: 639  -KKEKMKTE----LEREADEIEKIK--LETQHE-----RQRVEEMTADFMETMNNERKQL 686

Query: 1051 AQFTTKLENMEEEM-QRVSKQLLD-------SKQHNEELQILVRE-QDDQIKELKETKLT 1101
             +    +E  ++EM + +SKQ+ D       SK   +EL+ L  E Q  Q ++ +  KL 
Sbjct: 687  DKNKVMIEEQKQEMRENISKQIEDIENEKEKSKLREDELKKLQTEVQKQQKRDSESLKLD 746

Query: 1102 FEMNIPKTEGM-IISSTIEPMSDDANNV--DXXXXXXXXXXXXLKVQEEEEFIQE--RSV 1156
             E    + E M  + + ++  +D+   +  +             ++Q+E E I       
Sbjct: 747  KEAFENEKEAMKQMKTDLQIQADEIEKIKLETHHERQRVEEKTAQIQKEREEINTLVEEN 806

Query: 1157 LQEQSAKLNTELQ-------ECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTE 1209
             QE++ K  TE+Q       E    I   E+   +L    +  Q+++++LK+ +     +
Sbjct: 807  QQEKNKKTITEMQKERETLEEMRANISNRESELAKLQEDILQQQQEMDELKNTIMMEMCQ 866

Query: 1210 NDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYE 1269
             D   S +  L++ ++     +  E   L KQ +    A  ++ + EL+++    E K +
Sbjct: 867  LDQRQSDIDLLQNKLNL---HKELEELNLQKQGIQDERAQLERMKGELQMKADDIERKMQ 923

Query: 1270 QLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIED 1329
            ++L   Q   + ++           +Q  L +    ++ L ++       +E  + E++ 
Sbjct: 924  EILYEKQKYAERKSENY-------KIQTYLDEANAEVQKLNKELERYDENLEKCKLELDK 976

Query: 1330 EKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXX 1389
            +                    +   E Q  K+  ++S   + ++  ++K+          
Sbjct: 977  DIRRNLFKKEEAIEKDKAEKIESEREIQQEKKKLQRSEEELEDKMQKIKREMIELKLLQD 1036

Query: 1390 XXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFEN-----VRQQLVEY 1444
                +  D + K+ +   +++ +  +I        +   +RND  +N      ++Q++  
Sbjct: 1037 ETDGKRKDVDNKMRQQNDEIQKEKQQIESSK---MLLSRERNDLEQNRADLERQKQIMAL 1093

Query: 1445 EKR---IEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSL 1501
            +K+    E+   E+E    I  ++  E+     T ++ +E  +    EEL  ++ + ++ 
Sbjct: 1094 DKQKLLAENELLEREKADVIKIIENLESLREEATRERATETAQATKREELE-QLKDEINR 1152

Query: 1502 NKQVAELNKALEEEVAKTNEMQ--TALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVS 1559
             K+  E+ + L E V    EM+  T ++  + E+ ++ +E+   +  +   +S +Q  + 
Sbjct: 1153 EKEDVEIRRELVEAVIDKEEMKEFTDIQKYKEELQSVTEELLTKKRDLDQLNSDVQ-DLR 1211

Query: 1560 FASDTKQGRDEQLDNTMNKELLDAVPRAELDL 1591
               + ++   EQL   +N+E  D     E+D+
Sbjct: 1212 QTIEKEKEELEQLKKDINREKEDIETLEEVDI 1243



 Score =  117 bits (282), Expect = 2e-24
 Identities = 197/908 (21%), Positives = 414/908 (45%), Gaps = 92/908 (10%)

Query: 213  DTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEAN--KLLEAARFE-ISL 269
            D  Q  + +Q+    +E E K+E ++L KDI  +   I +LEE +   + + A  E I+ 
Sbjct: 1199 DLDQLNSDVQDLRQTIEKE-KEELEQLKKDINREKEDIETLEEVDIQYIKKKAELEHITS 1257

Query: 270  EHSKLAQELEQXXXXXXXXXXXXXXLA--KQSIEPSCE----EKTEIEEKG------SLE 317
            E  K  Q LE+              L   K ++E   E    EK  +EE         +E
Sbjct: 1258 EIQKREQILEKQKKNKNQIEQEKKDLQNMKSNLERQLESLRHEKANVEEIELKVKDLEME 1317

Query: 318  IANMTELTKKIE----LLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRK 373
            +A+M    ++IE    LLE    +++Q  KELE+++  +  E +      ++ + L++ K
Sbjct: 1318 MADMKRQKQEIEDTKGLLEKEKQELKQEKKELEDQMMDLTREKQETE---EERNNLMALK 1374

Query: 374  SGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDT 433
            +      K+KS   +L  E    D ++K   ++I  +E   + L K    K  ++++K  
Sbjct: 1375 NQLEDLRKIKS---ELVREKTEVDHEQKKLNDDIKMIEQEKEDLEKM---KSEIMTQKQE 1428

Query: 434  XXXXXXXXXXGKDTLIAQLQLEHQQ---HMEGPSLIHVGTNTEDVNEIAKVQ-EQLKQEL 489
                       ++T   +  LE      + +   L++     E   E  K Q E+++ E+
Sbjct: 1429 MEKERKEERRNEETRRLKEDLEKMSTDVNKQNKDLMNQRDLLEQEREEIKSQLERVRSEI 1488

Query: 490  NDEIKDVNV-KDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQM---QKTID 545
            + E K +N  K +IE+ K   E + ++  EI    + M + +S    K+KQ    +  I+
Sbjct: 1489 DHEQKKLNDDKKMIEQEK---EDLEKMKSEIMKQRQQMEEERSELDNKIKQTDLERHDIE 1545

Query: 546  NFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNL--QLHLVDYDSGRMI-ESDVYKKM 602
            N  ++    K +V + E+   +  +  EL+ E+  +  +  LV  +  ++  E++  K+M
Sbjct: 1546 NSKEIVQ--KLMVEVEEQRKDIRLQKEELDIERQKIADEQGLVVQNKAKLQNENERIKEM 1603

Query: 603  IEMENLAETRLKAISL-LESQKFDLVQELHILQQKYDEVEDKLA-DISQLQSDQVCS-EI 659
             E     +  LK +   L  +K ++   +   Q++  E  +K++ D+++   D +   ++
Sbjct: 1604 DEEIKKEKETLKEMEAHLRKEKEEMRSVIEETQRRQKEDLEKMSTDVNKQNQDLMNQRDL 1663

Query: 660  KSVHLEEQIDALSA--SKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQEN 717
                 EE+ID   A  SK++   + +  K+++E+     +DLE  K +IM + Q   +E 
Sbjct: 1664 LKQEREERIDEFDAQVSKQKEEDLTKQKKMEEEK-----EDLEKMKSEIMKQRQQMEEER 1718

Query: 718  MDLTDKLE--KMSAEKISELLAKINHE-EQSKIQTQFGIDAKIQERDLYIENIESELSKY 774
             +L +K E  K   E + E+ A +  E E+ K  T+   + + Q+ DL  E + + +++ 
Sbjct: 1719 SELENKNEVIKKERETLKEMEAYLEKEKEEMKSITE---ETRRQKEDL--EKMSTHINEQ 1773

Query: 775  KSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDEL-VNRLAVLMDH 833
            K  + R +  +  +E  R  +  K  QL   + E          +++EL + R  +  + 
Sbjct: 1774 KQDL-RSQRDL--LEQEREEINHKWKQLQQRIDEFDAQIKSQLERKEELDIERQKIADEQ 1830

Query: 834  DRVVEKQLLEIEHENKELQKKNQILLEENQNL---QISLSDMQQHYNALVEKA-NRTDLA 889
            D +++ ++ E ++EN+ +++ ++ + +E + L   +++L   ++   +++E+   R +  
Sbjct: 1831 DLLIQNKI-EQQNENERIKEMDEEIKKERETLKEMEVNLQKEKEEIESVIEETQRRKEDL 1889

Query: 890  ESESTKYQTQLRDLESN---LKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVL 946
            E  ST    Q +DL +    LK+   E    + Q ++ I++ E   N  + + + +K  +
Sbjct: 1890 EKMSTDINEQKQDLMNQRDLLKQEREEMNHKLTQLQQRIDEFETTSNILVTTKMEEKTEM 1949

Query: 947  NEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQ 1006
            +EK          L+  ++EY++ IE  N    EL ++  E  D   ++  ++    T +
Sbjct: 1950 DEK----------LQQAIKEYESIIEETNRKRTELEEIEKERKDTEKERGCSRGGTETGK 1999

Query: 1007 YINE-----INKLNALLKQ--KDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLEN 1059
               E     I+++  +L +  K+++ +  N++I   Q   +  +     ++ +    L+N
Sbjct: 2000 KGGEFERIQIDEVKRILSEIHKEKKELERNKQILEHQREALLEIKKEREEIEKMKADLQN 2059

Query: 1060 MEEEMQRV 1067
               E + +
Sbjct: 2060 KLREAENM 2067



 Score =  104 bits (249), Expect = 2e-20
 Identities = 168/907 (18%), Positives = 390/907 (42%), Gaps = 80/907 (8%)

Query: 731  KISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMED 790
            +I  L  ++  E++  ++ +  +D +  E D    N+   +   K     L+E + +M+ 
Sbjct: 4    EIQNLQQELEKEKEIIMKARSQLDLRQSELDKQQTNMNDIMETMKKS---LDEDLKMMKL 60

Query: 791  RRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKE 850
            ++  +E +  +L     E ++   E    ++E  N   +    +++ E    E E  +++
Sbjct: 61   QKQVIEEEKSKLKQMKIELEREADEIRKVKEETQNERQIF---EKMTEALKKEREDLSED 117

Query: 851  LQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRI 910
             ++KNQ+L E     + +L+D+ +  + L E          +    + ++R  E  LK++
Sbjct: 118  AKRKNQVLDEMKVANESTLADILRERSNLQEMRENISKQTEDVENKKEKIRLREEKLKQL 177

Query: 911  ---THEHQTLIVQKK-----------KEIEDLE---IEFNTQIESAIRDKKVLNEKYEKN 953
                H+ Q+   ++K           K++EDL+   I  +   ES   D++    + E+ 
Sbjct: 178  QAEIHKQQSETEKEKSNIERERAAIIKDVEDLQSKIISLDRDAESLKLDREAFENEKEEL 237

Query: 954  IEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLEL-IDKHVQKQQTQSPDYTEQY--INE 1010
             +  T+LE + +   N  + LN N EE+ +   E+  ++H   Q  +S D   +   + +
Sbjct: 238  KQMKTELEREAETMNNERKQLNKNKEEMQEQKQEMEKERHDMDQSRKSLDKNLKMMKLQK 297

Query: 1011 INKLNALLKQK---------DEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENME 1061
                + LL+ K         ++E+  L  +I+  Q        + ES+ A     +E+++
Sbjct: 298  QKTRSKLLRAKENLEKQRLREDELRQLQAEIHKQQREIEKEKINIESERAAIIKDVEDLQ 357

Query: 1062 EE---MQRVSKQL-LDSKQHNEELQIL---VREQDDQIKELKETKLTFEMNIPKTEGMII 1114
             +   + R ++ L LD ++ N +  +L    R+ +++IK ++  K   E    K +    
Sbjct: 358  HKIICLDRDAESLKLDREETNRKDMVLNEKNRDIEEKIKSIQSDKDMLEKE--KHDLEKT 415

Query: 1115 SSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTK 1174
             S +  + +D                    +  E   +E   ++ Q  ++N +  E    
Sbjct: 416  RSELYKVKEDLEKQKENTLAEIQKEREDLEKMNENITREMHEIKHQEEQMNQKQDELDQL 475

Query: 1175 IIQLETLNTELTGHDVV---NQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQR 1231
              +++ L  EL     +   ++ Q++  +S+L++  T  ++++ T+   R  +    ++ 
Sbjct: 476  KTEIQNLQQELEKEKEIIMKDRSQLDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEM 535

Query: 1232 GFEIAELWKQHL-AQREAD-----FQKTEHELRVQLSAFESKYE-QLLDSVQSSTQEETN 1284
              +  E+ K  +  +READ      ++T+++  ++    E++++ Q ++ + +  Q++  
Sbjct: 536  EEQKQEMEKMKIELEREADEISKIKEETQNKNEIEKIKLETQHDRQRVEEMAAQIQKKQV 595

Query: 1285 KIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXX 1344
                  ++  ++ +L+ + + +R ++E+  +    +E +  E++ EK+            
Sbjct: 596  FEEEKNKLEQMKIELEREADEIRKIKEETQNERQSLEKMTEELKKEKM--KTELEREADE 653

Query: 1345 XXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKS----SXXXXXXXXXXXXRVNDAE- 1399
                  + + E Q  ++M    +  +N E  QL K+                 ++ D E 
Sbjct: 654  IEKIKLETQHERQRVEEMTADFMETMNNERKQLDKNKVMIEEQKQEMRENISKQIEDIEN 713

Query: 1400 AKVLELTHQLELK--DSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKES 1457
             K      + ELK   +E+ ++    + +L    + FEN ++ + + +    DL  + + 
Sbjct: 714  EKEKSKLREDELKKLQTEVQKQQKRDSESLKLDKEAFENEKEAMKQMK---TDLQIQAD- 769

Query: 1458 ELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITES--VSLNKQVAELNKALEEE 1515
            E+  ++L+ H      E  +K ++I++ +  EE+N  + E+      K + E+ K  E E
Sbjct: 770  EIEKIKLETHHERQRVE--EKTAQIQKER--EEINTLVEENQQEKNKKTITEMQK--ERE 823

Query: 1516 VAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNT 1575
              +  EM+  + N+E E+  L ++I   Q  +    + I   +    D +Q   + L N 
Sbjct: 824  TLE--EMRANISNRESELAKLQEDILQQQQEMDELKNTIMMEMC-QLDQRQSDIDLLQNK 880

Query: 1576 MN--KEL 1580
            +N  KEL
Sbjct: 881  LNLHKEL 887



 Score = 97.5 bits (232), Expect = 3e-18
 Identities = 140/772 (18%), Positives = 331/772 (42%), Gaps = 75/772 (9%)

Query: 858  LLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHE---- 913
            L  E QNLQ    ++++    +++  ++ DL +SE  K QT + D+   +K+   E    
Sbjct: 1    LKTEIQNLQ---QELEKEKEIIMKARSQLDLRQSELDKQQTNMNDIMETMKKSLDEDLKM 57

Query: 914  ---HQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQ-LEAQLQEYKN 969
                + +I ++K +++ ++IE   + +  IR  K   +   +  E +T+ L+ + ++   
Sbjct: 58   MKLQKQVIEEEKSKLKQMKIELEREADE-IRKVKEETQNERQIFEKMTEALKKEREDLSE 116

Query: 970  NIENLNMNVEEL-------------NKMNLELIDKHVQKQQTQSPDYTEQYI----NEIN 1012
            + +  N  ++E+              + NL+ + +++ K QT+  +  ++ I     ++ 
Sbjct: 117  DAKRKNQVLDEMKVANESTLADILRERSNLQEMRENISK-QTEDVENKKEKIRLREEKLK 175

Query: 1013 KLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLL 1072
            +L A + ++  E       I   + + +  V D +SK+       E+++ + +    +  
Sbjct: 176  QLQAEIHKQQSETEKEKSNIERERAAIIKDVEDLQSKIISLDRDAESLKLDREAFENEKE 235

Query: 1073 DSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVD--X 1130
            + KQ   EL+      +++ K+L + K   EM   K E   +      M     ++D   
Sbjct: 236  ELKQMKTELEREAETMNNERKQLNKNK--EEMQEQKQE---MEKERHDMDQSRKSLDKNL 290

Query: 1131 XXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDV 1190
                        K+   +E ++++ + +++  +L  E+ +   + I+ E +N E     +
Sbjct: 291  KMMKLQKQKTRSKLLRAKENLEKQRLREDELRQLQAEIHK-QQREIEKEKINIESERAAI 349

Query: 1191 VNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELW------KQHLA 1244
            +  + +  L+ K+  L+ + ++L     E        ++++  +I E        K  L 
Sbjct: 350  I--KDVEDLQHKIICLDRDAESLKLDREETNRK-DMVLNEKNRDIEEKIKSIQSDKDMLE 406

Query: 1245 QREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQ--EETNKIVTM---------EQVT 1293
            + + D +KT  EL       E + E  L  +Q   +  E+ N+ +T          EQ+ 
Sbjct: 407  KEKHDLEKTRSELYKVKEDLEKQKENTLAEIQKEREDLEKMNENITREMHEIKHQEEQMN 466

Query: 1294 SLQNKLQDKEEHLRNLQ---EKYADVI----NQIEILRSEIEDEKVAFXXXXXXXXXXXX 1346
              Q++L   +  ++NLQ   EK  ++I    +Q+++ +SE++ ++               
Sbjct: 467  QKQDELDQLKTEIQNLQQELEKEKEIIMKDRSQLDLRQSELDKQQTNMNDIMETMKNERK 526

Query: 1347 XXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDA--EAKVLE 1404
                D + E +  KQ  E+  + +  E  ++ K              ++       +V E
Sbjct: 527  QLDKD-KEEMEEQKQEMEKMKIELEREADEISKIKEETQNKNEIEKIKLETQHDRQRVEE 585

Query: 1405 LTHQLELKD--SEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAIL 1462
            +  Q++ K    E   K  +  I L +  DE   ++++     + +E +T E + E   +
Sbjct: 586  MAAQIQKKQVFEEEKNKLEQMKIELEREADEIRKIKEETQNERQSLEKMTEELKKEK--M 643

Query: 1463 RLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEM 1522
            + ++   A+  E ++ E++ ER + +EE+     E+++  ++  + NK + EE  +  EM
Sbjct: 644  KTELEREADEIEKIKLETQHERQR-VEEMTADFMETMNNERKQLDKNKVMIEE--QKQEM 700

Query: 1523 QTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDN 1574
            +  +  Q  +I    ++    ++ ++   +++QK     S++ +   E  +N
Sbjct: 701  RENISKQIEDIENEKEKSKLREDELKKLQTEVQKQQKRDSESLKLDKEAFEN 752



 Score = 93.5 bits (222), Expect = 4e-17
 Identities = 145/753 (19%), Positives = 327/753 (43%), Gaps = 54/753 (7%)

Query: 148  SNTIKEKDNALSVLQVKMKIM-ETTILDL-QEKINEKDQIIEA-KNKATTXXXXXXXXXX 204
            +N +  K+    + ++K +++ E T +D  Q+K+N+  ++IE  K               
Sbjct: 1368 NNLMALKNQLEDLRKIKSELVREKTEVDHEQKKLNDDIKMIEQEKEDLEKMKSEIMTQKQ 1427

Query: 205  XXXXXXXEDTKQQMTK-MQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAA 263
                   E+ + + T+ ++E+   M  +   + + L+     +D+     EE    LE  
Sbjct: 1428 EMEKERKEERRNEETRRLKEDLEKMSTDVNKQNKDLMNQ---RDLLEQEREEIKSQLERV 1484

Query: 264  RFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTE 323
            R EI  E  KL  + +               + KQ  +   EE++E++ K         +
Sbjct: 1485 RSEIDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQRQQME-EERSELDNKIKQTDLERHD 1543

Query: 324  LTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMK 383
            +    E+++ L  ++ +  K++  +   +  E + ++   ++G  + ++   +N   ++K
Sbjct: 1544 IENSKEIVQKLMVEVEEQRKDIRLQKEELDIERQKIAD--EQGLVVQNKAKLQNENERIK 1601

Query: 384  SPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXX 443
                         + D++I K +    EM    L K+  +   VI E             
Sbjct: 1602 -------------EMDEEIKKEKETLKEMEAH-LRKEKEEMRSVIEETQRRQKEDL---- 1643

Query: 444  GKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEI-AKVQEQLKQELNDEIKDVNVKDLI 502
              + +   +  ++Q  M    L+      E ++E  A+V +Q +++L  + K    K+ +
Sbjct: 1644 --EKMSTDVNKQNQDLMNQRDLLKQ-EREERIDEFDAQVSKQKEEDLTKQKKMEEEKEDL 1700

Query: 503  EKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDS-NKEIVRLT 561
            EK+KS   +  Q  +E  +  +N  +V    +  LK+M+  ++   +   S  +E  R  
Sbjct: 1701 EKMKSEIMKQRQQMEEERSELENKNEVIKKERETLKEMEAYLEKEKEEMKSITEETRRQK 1760

Query: 562  EELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIES--DVYKKMIEMENLAETRLKAISLL 619
            E+L  +S  + E +++  + Q  L++ +   +      + +++ E +   +++L+    L
Sbjct: 1761 EDLEKMSTHINEQKQDLRS-QRDLLEQEREEINHKWKQLQQRIDEFDAQIKSQLERKEEL 1819

Query: 620  ESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELA 679
            + ++  +  E  +L Q   E +++   I ++  +++  E ++  L+E    L   K+E+ 
Sbjct: 1820 DIERQKIADEQDLLIQNKIEQQNENERIKEMD-EEIKKERET--LKEMEVNLQKEKEEIE 1876

Query: 680  LVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKI 739
             VIE  +  KE L     D+   K+D+MN+     QE  ++  KL ++  ++I E     
Sbjct: 1877 SVIEETQRRKEDLEKMSTDINEQKQDLMNQRDLLKQEREEMNHKLTQLQ-QRIDEFETTS 1935

Query: 740  NHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKA 799
            N    +K++ +  +D K+Q+     E+I  E ++ ++ +  +E+     E +    ER  
Sbjct: 1936 NILVTTKMEEKTEMDEKLQQAIKEYESIIEETNRKRTELEEIEK-----ERKDTEKERGC 1990

Query: 800  DQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILL 859
             + G+   +K   +    IQ DE+   L+ +    + +E+    +EH+ + L +    + 
Sbjct: 1991 SRGGTETGKKGGEFER--IQIDEVKRILSEIHKEKKELERNKQILEHQREALLE----IK 2044

Query: 860  EENQNLQISLSDMQQHYNALVEKANRTDLAESE 892
            +E + ++   +D+Q   N L E  N  D+ + E
Sbjct: 2045 KEREEIEKMKADLQ---NKLREAENMRDIMKRE 2074



 Score = 44.4 bits (100), Expect = 0.026
 Identities = 57/320 (17%), Positives = 126/320 (39%), Gaps = 15/320 (4%)

Query: 1295 LQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRT 1354
            L+ ++Q+ ++ L   +E      +Q+++ +SE++ ++                    ++ 
Sbjct: 1    LKTEIQNLQQELEKEKEIIMKARSQLDLRQSELDKQQTNMNDIMETMKKSLDEDLKMMKL 60

Query: 1355 ENQ---SYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLEL 1411
            + Q     K   +Q  + +  E  +++K                   + +  +L+   + 
Sbjct: 61   QKQVIEEEKSKLKQMKIELEREADEIRKVKEETQNERQIFEKMTEALKKEREDLSEDAKR 120

Query: 1412 KDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKES------ELAILRLK 1465
            K+  + +       TL     E  N+++      K+ ED+  +KE       +L  L+ +
Sbjct: 121  KNQVLDEMKVANESTLADILRERSNLQEMRENISKQTEDVENKKEKIRLREEKLKQLQAE 180

Query: 1466 MHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAEL---NKALEEEVAKTNEM 1522
            +H+  +  E  +   E ER  +I+++    ++ +SL++    L    +A E E  +  +M
Sbjct: 181  IHKQQSETEKEKSNIERERAAIIKDVEDLQSKIISLDRDAESLKLDREAFENEKEELKQM 240

Query: 1523 QTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLD 1582
            +T LE    E  T+N+E   L         + Q+      D  Q R     N    +L  
Sbjct: 241  KTELER---EAETMNNERKQLNKNKEEMQEQKQEMEKERHDMDQSRKSLDKNLKMMKLQK 297

Query: 1583 AVPRAELDLAMYMLHQRDVR 1602
               R++L  A   L ++ +R
Sbjct: 298  QKTRSKLLRAKENLEKQRLR 317


>UniRef50_UPI00006CB2DA Cluster: Viral A-type inclusion protein repeat
            containing protein; n=1; Tetrahymena thermophila
            SB210|Rep: Viral A-type inclusion protein repeat
            containing protein - Tetrahymena thermophila SB210
          Length = 2199

 Score =  184 bits (449), Expect = 1e-44
 Identities = 293/1474 (19%), Positives = 629/1474 (42%), Gaps = 130/1474 (8%)

Query: 158  LSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKA---TTXXXXXXXXXXXXXXXXXEDT 214
            + +L+ ++K    TI D  E I  K  +IE KNK                       E+ 
Sbjct: 524  IKILEEQIKDYVETIKDKNEIIQAKSNLIEEKNKVIQMNDILIAENEELMKSNTDKIEEL 583

Query: 215  KQQMTKMQENFIAMEAEWKDEKQRLLKDIESK-DVRISSLEEANKLLEAARFEISLEHSK 273
             +Q+ +  +  + +E +  + K+   K ++   D+ ++   +    LE    +I  + ++
Sbjct: 584  DEQILEKDKKILQLEIDLDNVKKGFEKVLQQNTDMYMNQKSDTLSQLENLTNKIQEQSNE 643

Query: 274  LAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEH 333
            L ++L++              L K  I  + +EK +  E    +  N  ++T K   +E 
Sbjct: 644  LDEKLDEIADLNNTI------LDKDKIIRTYKEKIDQYEADLKQ--NKEQITSKTLEIEK 695

Query: 334  LNCQI---RQTNKELENKLATMGTESKAVSSPSKKGSPLISR--KSGRNTASK---MKSP 385
            L  QI      N+  +  LA    E  ++     K + L+ +  KS      K   MK  
Sbjct: 696  LTEQIGFLELENERFQQVLAHTQVERMSIKHEFDKDTELLQQQLKSAMGEYIKKIEMKDF 755

Query: 386  WSQLSSETLNQDT-DKKINKNEIAKLEMVIQSLNKDL-----VDKEYVISEKDTXXXXXX 439
              Q  +E +N        ++ EI K   +I+ LN D+     + K  +            
Sbjct: 756  EIQGQAEQINNLVIQMNTHQEEITKKNQIIEDLNNDISRLSNIQKSQLCQISILNEFCLS 815

Query: 440  XXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVK 499
                 +   +   +L ++ +    +        E++N   +  E LK+ L  E  ++  +
Sbjct: 816  NNQNEQILKMVPKRLIYRLYKLQANQKFNLIFQEEINTYTQEIETLKENLKKE--ELKSQ 873

Query: 500  DLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVR 559
            DL E  K+ E+QI Q    I   ++ + +++   +    ++Q   D   K++ S +E  +
Sbjct: 874  DLEESKKNQEDQIKQQEQNIKELHEKLKEIEKRQEEINTEIQNLKDEKEKLTQSIEEDKK 933

Query: 560  LTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLL 619
            + EE   L++ +++ ++E   +Q   V+          + +K+ E+E     +   I+ L
Sbjct: 934  VIEE---LNKSISQKDDELKEIQQQCVN----------LKQKIEELEKDVSDKTSEINQL 980

Query: 620  ESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELA 679
                 DL++  H  Q+K D+ ED L      QS +   E     L+++I+ +    ++  
Sbjct: 981  N----DLIKN-H--QEKIDQQEDSL------QSKEKTIEETKEELKKKIEVIEKLHEQFN 1027

Query: 680  LVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKI 739
               + L    +++   I++ +  ++++  K QN I E   + ++ E++    I E   K+
Sbjct: 1028 ETNQTLGQRAQEIEQIIENKQQKEKELQEK-QNKIDEKQKIIEEKEEI----IKENEQKL 1082

Query: 740  NHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKA 799
                +   + Q  I+ K+ E+       E+E+ + + ++   EE +A  ++   + +++ 
Sbjct: 1083 KQANEQLEENQNAIN-KLSEQQT---QSEAEIKQLQEKLKDTEELLASAKENLQNSQKEL 1138

Query: 800  DQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILL 859
            +Q    L +KQK Y E    E ELV + A  + +   +EK++ ++  + + L+++++  +
Sbjct: 1139 EQSQESLSQKQKLYDE----EHELVQKKAEQITN---LEKEISKLNEDLESLKQEHKSFI 1191

Query: 860  EE-NQNLQISLSDMQQHYNA----LVEKANRTDLAESESTKYQTQLRDLESNLKRITHEH 914
            E  N++ Q  +  + Q  N     + E   + D   SES++   Q+ D    ++++  + 
Sbjct: 1192 ENTNKSHQEQIDSLNQQINQFKQNISENQKQIDQLNSESSQKSNQISDKNEEIQQLKGKI 1251

Query: 915  QTL---IVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNI 971
            +TL   +  +KK  ++L+I+   Q E++   K +L +   +  + +  L ++  +     
Sbjct: 1252 ETLNEDLNSQKKTADELKIQLTAQQENSKEIKNMLQQTESQRDKLMDNLNSKDSQTAQLN 1311

Query: 972  ENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQK 1031
            + L   +E  N+  ++ I    +K + Q     EQ   EI  +N  L+Q  +++     K
Sbjct: 1312 QKLG-TLESQNEQQIKKISSQKEKIK-QLKASLEQNNLEIQSINKQLEQTKQDLQKEQNK 1369

Query: 1032 INNAQVSYMSMVSDYESKLAQFT-TKLEN---MEEEMQRVSKQLLDSKQHNEELQILVRE 1087
              N      S +   +SK+A+    K +N   +  E Q+ S+   D     E+LQ L + 
Sbjct: 1370 YENTSGQQSSTIEQLKSKIAELEQAKSQNEQTISSEKQKNSQLEKDQNSIKEDLQTLQQT 1429

Query: 1088 QDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEE 1147
              ++  ELK   L+ E+   K EG      I+ +S   +N +                E+
Sbjct: 1430 LKEKQNELKN--LSSEIEKFKEEGKSSKQQIDELSK--SNEENLSQINSLNIQIQVFSEQ 1485

Query: 1148 EEFIQERSVLQEQS-AKLNTELQ--ECYTKIIQLETL--NTELTGHDVVNQEQINQLKSK 1202
             E I      ++Q+ +KLN +    E   K +Q++    + ++       +++I QL S 
Sbjct: 1486 NETISAELTKKDQTISKLNEQNSQFEIDIKTLQMKIREQSEQMNEEKEFQEKKIQQLNST 1545

Query: 1203 LEQLNTENDNLLSTV-AELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQL 1261
            ++QL  +  + + T+ A+L+  I  +  +  F+  +  K  L +     Q      R Q+
Sbjct: 1546 IDQLKLQIKSQVETINAKLKEKIQES--ENAFDELDTTKTELLK----LQDIIDGQRSQI 1599

Query: 1262 SAFESKYEQLLDSVQSSTQEETNKIVTME-QVTSLQNKLQDKEEHLRNLQEKYADVINQI 1320
               +++ E+L + + S   EE  K  +   ++ + + K++   E ++ LQEK      Q 
Sbjct: 1600 ITLQNELEKL-NQLNSQLLEEKMKAESYHVKIQNQEEKIKSNAEMIQVLQEKLKTSEQQA 1658

Query: 1321 EILRSEI-------EDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEE 1373
             +L+ ++       +D++                    L  + Q + Q + +  + IN  
Sbjct: 1659 NLLKQQLKNKQYQEDDQQRETRKSVSFLTSQAEMNKYQLDNQKQKWDQQEAEYKIKINSL 1718

Query: 1374 NAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQL-ELK---------DSEIYQKTHEY 1423
            NAQ+++               + + E+ V++    L +LK         +  + QK  E 
Sbjct: 1719 NAQIQQLIEEKQSNIDMKKSFMKERESVVVDKEKALRDLKQLYAQSRKNEESLEQKISEM 1778

Query: 1424 TITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIE 1483
               +   N E E++R QL+   ++IE + Y ++ E +  +     +AN  + +Q+ES + 
Sbjct: 1779 EKVILNMNQEIESLRTQLIRANQQIEQMAYARKYEAS--QYADLRSANLSKALQQES-LP 1835

Query: 1484 RVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTA-LENQEIEIVTLNDEITN 1542
             +  I++    + E   LN  ++++N +  ++ A+ + +  A L N+ + ++   D+  N
Sbjct: 1836 TLNNIQKQGSNMGE---LN--LSQINHSFTQKDAEDDNIMLADLANEILSLIQQGDQQNN 1890

Query: 1543 LQNMVRASS--SKIQKHVSFASDTKQGRDEQLDN 1574
              N+ +++S   +I     F + T +  ++ L +
Sbjct: 1891 EANLKQSASVGGEIANSSQFVTFTPEDENQILSS 1924



 Score =  182 bits (442), Expect = 1e-43
 Identities = 306/1488 (20%), Positives = 619/1488 (41%), Gaps = 137/1488 (9%)

Query: 174  DLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWK 233
            DL  K+ + ++ +E+KN   T                 E+T  Q+ ++Q   +   A  +
Sbjct: 270  DLTTKLQDLNKELESKNNEYTQNLEQKEKEIQLQQKQAEETTSQL-QLQIQTLKQSANQE 328

Query: 234  -----DEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXX 288
                 ++ +  L +I  ++++   L E N L++    +I+ +H K   E+E         
Sbjct: 329  NLNLNEQFEEKLNNIREQELQKFKLAEENHLIQIE--QITTKHKKEISEIESS------- 379

Query: 289  XXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENK 348
                  + K +++ S +   +IEE   L I ++ +  + I+ +E +  + ++  K +  K
Sbjct: 380  ------IKKLTLD-SNKRYQQIEEVHLLSIESLKQ--QHIKTIEAMKAEQQENEKSIRQK 430

Query: 349  ----LATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINK 404
                L  +  E KA+   ++K   L S +   N  S ++     L      Q+ + K  K
Sbjct: 431  YEKHLDRLQDEIKAIQEANQK---LNSEQE--NKISNLEGQIKDLEKSKNKQNEEIKQLK 485

Query: 405  NEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPS 464
            N++ +       ++  +V  E  +S +D+           K  L  Q++   +   +   
Sbjct: 486  NKLNEKNEKFDIMSTSIVSTES-LSVRDSDLKTTEYIKKIK-ILEEQIKDYVETIKDKNE 543

Query: 465  LIHVGTNT-EDVNEIAKVQEQLKQELNDEIKDVN---VKDLIEKLKSAEEQITQLNDEID 520
            +I   +N  E+ N++ ++ + L  E N+E+   N   +++L E++   +++I QL  ++D
Sbjct: 544  IIQAKSNLIEEKNKVIQMNDILIAE-NEELMKSNTDKIEELDEQILEKDKKILQLEIDLD 602

Query: 521  AANKNMIKV-KSNHKLKLKQMQKTIDNF----SKVSDSNKEIVRLTEELHHLSQKVAELE 575
               K   KV + N  + + Q   T+       +K+ + + E+    +E+  L+  + + +
Sbjct: 603  NVKKGFEKVLQQNTDMYMNQKSDTLSQLENLTNKIQEQSNELDEKLDEIADLNNTILDKD 662

Query: 576  EEKGNLQLHLVDYDSG-RMIESDVYKKMIEMENLAETRLKAISLLESQKFDLV-QELHIL 633
            +     +  +  Y++  +  +  +  K +E+E L E ++  + L E+++F  V     + 
Sbjct: 663  KIIRTYKEKIDQYEADLKQNKEQITSKTLEIEKLTE-QIGFLEL-ENERFQQVLAHTQVE 720

Query: 634  QQKYDEVEDKLADISQLQSDQVCSE-IKSVHLEE-QIDALSASKKELALVIENLKLDKEQ 691
            +       DK  ++ Q Q      E IK + +++ +I   +     L + +   + +  +
Sbjct: 721  RMSIKHEFDKDTELLQQQLKSAMGEYIKKIEMKDFEIQGQAEQINNLVIQMNTHQEEITK 780

Query: 692  LYGTIKDLENDKEDIMNKLQNYIQENMDLTDK-LEKMSAEKISELLAKINHEEQSKIQTQ 750
                I+DL ND   + N  ++ + +   L +  L     E+I +++ K       K+Q  
Sbjct: 781  KNQIIEDLNNDISRLSNIQKSQLCQISILNEFCLSNNQNEQILKMVPKRLIYRLYKLQAN 840

Query: 751  FGIDAKIQER-DLY---IENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYL 806
               +   QE  + Y   IE ++  L K + +   LEES    ED+    E+   +L   L
Sbjct: 841  QKFNLIFQEEINTYTQEIETLKENLKKEELKSQDLEESKKNQEDQIKQQEQNIKELHEKL 900

Query: 807  QEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQ--- 863
            +E +K   E   +   L +    L      +E+    IE  NK + +K+  L E  Q   
Sbjct: 901  KEIEKRQEEINTEIQNLKDEKEKLTQS---IEEDKKVIEELNKSISQKDDELKEIQQQCV 957

Query: 864  NLQISLSDMQQHYNALVEKANR-TDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKK 922
            NL+  + ++++  +    + N+  DL ++   K   Q   L+S  K I    + L    K
Sbjct: 958  NLKQKIEELEKDVSDKTSEINQLNDLIKNHQEKIDQQEDSLQSKEKTIEETKEEL----K 1013

Query: 923  KEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEEL- 981
            K+IE +E + + Q     +      ++ E+ IE   Q E +LQE +N I+     +EE  
Sbjct: 1014 KKIEVIE-KLHEQFNETNQTLGQRAQEIEQIIENKQQKEKELQEKQNKIDEKQKIIEEKE 1072

Query: 982  -----NKMNLELIDKHVQKQQTQSPDYTEQYIN---EINKLNALLKQKDEEIIALNQKIN 1033
                 N+  L+  ++ +++ Q      +EQ      EI +L   LK  +E + +  + + 
Sbjct: 1073 EIIKENEQKLKQANEQLEENQNAINKLSEQQTQSEAEIKQLQEKLKDTEELLASAKENLQ 1132

Query: 1034 NAQ---------VSYMSMVSDYESKLAQFTTK-LENMEEEMQRVSKQLLDSKQ-HNEELQ 1082
            N+Q         +S    + D E +L Q   + + N+E+E+ ++++ L   KQ H   ++
Sbjct: 1133 NSQKELEQSQESLSQKQKLYDEEHELVQKKAEQITNLEKEISKLNEDLESLKQEHKSFIE 1192

Query: 1083 ILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXL 1142
               +   +QI  L +    F+ NI + +  I     E  S  +N +             +
Sbjct: 1193 NTNKSHQEQIDSLNQQINQFKQNISENQKQIDQLNSES-SQKSNQISDKNEEIQQLKGKI 1251

Query: 1143 KVQEEEEFIQERSV--LQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLK 1200
            +   E+   Q+++   L+ Q        +E    + Q E+   +L  +      Q  QL 
Sbjct: 1252 ETLNEDLNSQKKTADELKIQLTAQQENSKEIKNMLQQTESQRDKLMDNLNSKDSQTAQLN 1311

Query: 1201 SKLEQLNTENDNLLSTVAELRSSIS---SAVDQRGFEIAELWKQHLAQREADFQKTEHEL 1257
             KL  L ++N+  +  ++  +  I    ++++Q   EI  + KQ L Q + D QK +++ 
Sbjct: 1312 QKLGTLESQNEQQIKKISSQKEKIKQLKASLEQNNLEIQSINKQ-LEQTKQDLQKEQNKY 1370

Query: 1258 RVQLSAFESKYEQLLDSV----QSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKY 1313
                    S  EQL   +    Q+ +Q E       ++ + L+      +E L+ LQ+  
Sbjct: 1371 ENTSGQQSSTIEQLKSKIAELEQAKSQNEQTISSEKQKNSQLEKDQNSIKEDLQTLQQTL 1430

Query: 1314 ADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQ---------- 1363
             +  N+++ L SEIE  K                   +L   N    Q+Q          
Sbjct: 1431 KEKQNELKNLSSEIEKFKEEGKSSKQQIDELSKSNEENLSQINSLNIQIQVFSEQNETIS 1490

Query: 1364 ------EQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDA----EAKVLELTHQLELKD 1413
                  +Q+I  +NE+N+Q +               ++N+     E K+ +L   ++   
Sbjct: 1491 AELTKKDQTISKLNEQNSQFEIDIKTLQMKIREQSEQMNEEKEFQEKKIQQLNSTIDQLK 1550

Query: 1414 SEIYQKTHEYTITLTQRNDEFENVRQQLVEYEK---RIEDLTYEKESELAILRLKMHENA 1470
             +I  +       L ++  E EN   +L   +    +++D+   + S++  L+ ++ E  
Sbjct: 1551 LQIKSQVETINAKLKEKIQESENAFDELDTTKTELLKLQDIIDGQRSQIITLQNEL-EKL 1609

Query: 1471 NHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQE 1530
            N   +   E   E++K  E  +VKI       K  AE+ + L+E++ KT+E Q  L  Q+
Sbjct: 1610 NQLNSQLLE---EKMKA-ESYHVKIQNQEEKIKSNAEMIQVLQEKL-KTSEQQANLLKQQ 1664

Query: 1531 IEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNK 1578
            ++         N Q        + +K VSF +   +    QLDN   K
Sbjct: 1665 LK---------NKQYQEDDQQRETRKSVSFLTSQAEMNKYQLDNQKQK 1703



 Score =  177 bits (432), Expect = 2e-42
 Identities = 255/1341 (19%), Positives = 582/1341 (43%), Gaps = 108/1341 (8%)

Query: 305  EEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSK 364
            ++K +  E  S E  N  +  + +   +      + ++K+ +N    +G+  +  S   K
Sbjct: 88   DKKNKDSESESDEEQNNKQERQSVMAKKQKESDDQHSDKQSDNDDNLLGSSDE--SGDEK 145

Query: 365  KGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLV-D 423
            K      ++  +N   K +    ++ +E  +Q         + A  E+    LNK ++ D
Sbjct: 146  KEQQ--KKEKQKNKKDKKEQTHLKVENERTSQGLKISAMIRKGADQEV---DLNKPILED 200

Query: 424  KEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQE 483
             +    ++              D  +AQL +E Q+  E   L       +++  +    +
Sbjct: 201  SDEEQQQQQENKSSKVMSNTQIDDKLAQLTVEVQRLTEENKL-----KLKEIETLTYTID 255

Query: 484  QLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKT 543
             LK+E+ D  K+ N +DL  KL+   +++   N+E     +N+ + +   +L+ KQ ++T
Sbjct: 256  DLKEEV-DHSKEEN-QDLTTKLQDLNKELESKNNEY---TQNLEQKEKEIQLQQKQAEET 310

Query: 544  IDNF-----SKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNL--QLHLVDYDSGRMIES 596
                     +    +N+E + L E+       + E E +K  L  + HL+       IE 
Sbjct: 311  TSQLQLQIQTLKQSANQENLNLNEQFEEKLNNIREQELQKFKLAEENHLIQ------IEQ 364

Query: 597  DVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVC 656
               K   E+  + E+ +K ++L  ++++  ++E+H+L  +  + +  +  I  ++++Q  
Sbjct: 365  ITTKHKKEISEI-ESSIKKLTLDSNKRYQQIEEVHLLSIESLK-QQHIKTIEAMKAEQQE 422

Query: 657  SEIKSVH--LEEQIDALSASKKELALVIENLKLDKEQ------LYGTIKDLENDKEDIMN 708
            +E KS+    E+ +D L    K  A+   N KL+ EQ      L G IKDLE  K     
Sbjct: 423  NE-KSIRQKYEKHLDRLQDEIK--AIQEANQKLNSEQENKISNLEGQIKDLEKSKNKQNE 479

Query: 709  KLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDL--YIEN 766
            +++    +  +  +K + MS   +S     +   +     T++    KI E  +  Y+E 
Sbjct: 480  EIKQLKNKLNEKNEKFDIMSTSIVSTESLSVRDSDLKT--TEYIKKIKILEEQIKDYVET 537

Query: 767  IE--SELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELV 824
            I+  +E+ + KS +   +  +  M D    L  + ++L     +K +   E  +++D+ +
Sbjct: 538  IKDKNEIIQAKSNLIEEKNKVIQMND---ILIAENEELMKSNTDKIEELDEQILEKDKKI 594

Query: 825  NRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEEN--QNLQISLSDMQQHYNALVEK 882
             +L + +D+ +   +++L+   +    QK + +   EN    +Q   +++ +  + + + 
Sbjct: 595  LQLEIDLDNVKKGFEKVLQQNTDMYMNQKSDTLSQLENLTNKIQEQSNELDEKLDEIAD- 653

Query: 883  ANRTDLAESESTK-YQTQLRDLESNLKRITHE--HQTLIVQKKKE-IEDLEIEFNTQIES 938
             N T L + +  + Y+ ++   E++LK+   +   +TL ++K  E I  LE+E N + + 
Sbjct: 654  LNNTILDKDKIIRTYKEKIDQYEADLKQNKEQITSKTLEIEKLTEQIGFLELE-NERFQQ 712

Query: 939  AIRDKKV----LNEKYEKNIEYVTQ-LEAQLQEYKNNIENLNMNV----EELNKMNLELI 989
             +   +V    +  +++K+ E + Q L++ + EY   IE  +  +    E++N + +++ 
Sbjct: 713  VLAHTQVERMSIKHEFDKDTELLQQQLKSAMGEYIKKIEMKDFEIQGQAEQINNLVIQM- 771

Query: 990  DKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKI--NNAQVSYMSMVSD-- 1045
            + H Q++ T+     E   N+I++L+ + K +  +I  LN+    NN     + MV    
Sbjct: 772  NTH-QEEITKKNQIIEDLNNDISRLSNIQKSQLCQISILNEFCLSNNQNEQILKMVPKRL 830

Query: 1046 ----YESKLAQ-----FTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELK 1096
                Y+ +  Q     F  ++    +E++ + + L   +  +++L+   + Q+DQIK+ +
Sbjct: 831  IYRLYKLQANQKFNLIFQEEINTYTQEIETLKENLKKEELKSQDLEESKKNQEDQIKQQE 890

Query: 1097 ETKLTFEMNIPKTEGMI--ISSTIEPMSDDANNVDXXXXXXXXXXXXLK--VQEEEEFIQ 1152
            +        + + E     I++ I+ + D+   +             L   + ++++ ++
Sbjct: 891  QNIKELHEKLKEIEKRQEEINTEIQNLKDEKEKLTQSIEEDKKVIEELNKSISQKDDELK 950

Query: 1153 ERSVLQEQSAKLNTELQECYT----KIIQLETLNTELTGHDVVNQEQINQLKSK---LEQ 1205
            E   +Q+Q   L  +++E       K  ++  LN  +  H     +Q + L+SK   +E+
Sbjct: 951  E---IQQQCVNLKQKIEELEKDVSDKTSEINQLNDLIKNHQEKIDQQEDSLQSKEKTIEE 1007

Query: 1206 LNTENDNLLSTVAELRSSISSA---VDQRGFEIAELWKQHLAQREADFQKTEHELRVQLS 1262
               E    +  + +L    +     + QR  EI ++  ++  Q+E + Q+ ++++  +  
Sbjct: 1008 TKEELKKKIEVIEKLHEQFNETNQTLGQRAQEIEQII-ENKQQKEKELQEKQNKIDEKQK 1066

Query: 1263 AFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEI 1322
              E K E + ++ Q   Q           +  L  +    E  ++ LQEK  D    +  
Sbjct: 1067 IIEEKEEIIKENEQKLKQANEQLEENQNAINKLSEQQTQSEAEIKQLQEKLKDTEELLAS 1126

Query: 1323 LRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQ--EQSILNINEENAQLKKS 1380
             +  +++ +                   +     +  +Q+   E+ I  +NE+   LK+ 
Sbjct: 1127 AKENLQNSQKELEQSQESLSQKQKLYDEEHELVQKKAEQITNLEKEISKLNEDLESLKQE 1186

Query: 1381 -SXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQ 1439
                          +++    ++ +    +     +I Q   E +    Q +D+ E ++Q
Sbjct: 1187 HKSFIENTNKSHQEQIDSLNQQINQFKQNISENQKQIDQLNSESSQKSNQISDKNEEIQQ 1246

Query: 1440 QLVEYEKRIEDLTYEKES--ELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITE 1497
               + E   EDL  +K++  EL I      EN+   + M +++E +R KL++ LN K ++
Sbjct: 1247 LKGKIETLNEDLNSQKKTADELKIQLTAQQENSKEIKNMLQQTESQRDKLMDNLNSKDSQ 1306

Query: 1498 SVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKH 1557
            +  LN+++  L    E+++ K +  +  ++  +  +   N EI ++   +  +   +QK 
Sbjct: 1307 TAQLNQKLGTLESQNEQQIKKISSQKEKIKQLKASLEQNNLEIQSINKQLEQTKQDLQKE 1366

Query: 1558 VSFASDTKQGRDEQLDNTMNK 1578
             +   +T   +   ++   +K
Sbjct: 1367 QNKYENTSGQQSSTIEQLKSK 1387



 Score =  148 bits (358), Expect = 1e-33
 Identities = 254/1277 (19%), Positives = 548/1277 (42%), Gaps = 110/1277 (8%)

Query: 383  KSPWSQLSSETLNQDTDKKINKNEIAKLE-MVIQSLNKDLVDKEYVISEKDTXXXXXXXX 441
            KS   Q+ S+  N+D++ + ++ +  K E   + +  +   D ++   + D         
Sbjct: 79   KSVNFQIFSDKKNKDSESESDEEQNNKQERQSVMAKKQKESDDQHSDKQSDNDDNLLGSS 138

Query: 442  XXGKDTLIAQLQLEHQQHMEGPS-LIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVN--- 497
                D    Q + E Q++ +      H+    E  ++  K+   +++  + E+ D+N   
Sbjct: 139  DESGDEKKEQQKKEKQKNKKDKKEQTHLKVENERTSQGLKISAMIRKGADQEV-DLNKPI 197

Query: 498  VKDLIEKLKSAEEQI-------TQLNDEIDAANKNMIKVKSNHKLKLKQMQK---TIDNF 547
            ++D  E+ +  +E         TQ++D++      + ++   +KLKLK+++    TID+ 
Sbjct: 198  LEDSDEEQQQQQENKSSKVMSNTQIDDKLAQLTVEVQRLTEENKLKLKEIETLTYTIDDL 257

Query: 548  SKVSDSNKEIVR-LTEELHHLSQKVAE--------LEEEKGNLQLHLVDYD---SGRMIE 595
             +  D +KE  + LT +L  L++++          LE+++  +QL     +   S   ++
Sbjct: 258  KEEVDHSKEENQDLTTKLQDLNKELESKNNEYTQNLEQKEKEIQLQQKQAEETTSQLQLQ 317

Query: 596  SDVYKKMIEMENLA-----ETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQL 650
                K+    ENL      E +L  I   E QKF L +E H++Q +    + K  +IS++
Sbjct: 318  IQTLKQSANQENLNLNEQFEEKLNNIREQELQKFKLAEENHLIQIEQITTKHK-KEISEI 376

Query: 651  QSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKL 710
            +S      IK + L+         +  L L IE+LK   +Q   TI+ ++ ++++    +
Sbjct: 377  ESS-----IKKLTLDSNKRYQQIEEVHL-LSIESLK---QQHIKTIEAMKAEQQENEKSI 427

Query: 711  QNYIQENMD-LTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIES 769
            +   ++++D L D+++      I E   K+N E+++KI     ++ +I++ +        
Sbjct: 428  RQKYEKHLDRLQDEIKA-----IQEANQKLNSEQENKISN---LEGQIKDLEKSKNKQNE 479

Query: 770  ELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAV 829
            E+ + K+++    E   +M     S E  + +  S L+  +    +  I E+++ + +  
Sbjct: 480  EIKQLKNKLNEKNEKFDIMSTSIVSTESLSVR-DSDLKTTEYI-KKIKILEEQIKDYVET 537

Query: 830  LMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSD-MQQHYNALVEKANRT-- 886
            + D + +++ +   IE +NK +Q  N IL+ EN+ L  S +D +++    ++EK  +   
Sbjct: 538  IKDKNEIIQAKSNLIEEKNKVIQM-NDILIAENEELMKSNTDKIEELDEQILEKDKKILQ 596

Query: 887  -----DLAESESTKYQTQLRDLESNLKRITH---EHQTLIVQKKKEIEDLEIEFNTQIES 938
                 D  +    K   Q  D+  N K  T    E+ T  +Q++    D +++    + +
Sbjct: 597  LEIDLDNVKKGFEKVLQQNTDMYMNQKSDTLSQLENLTNKIQEQSNELDEKLDEIADLNN 656

Query: 939  AIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMN--LELIDKHVQKQ 996
             I DK  +   Y++ I+   Q EA L++ K  I +  + +E+L +    LEL ++  Q+ 
Sbjct: 657  TILDKDKIIRTYKEKID---QYEADLKQNKEQITSKTLEIEKLTEQIGFLELENERFQQV 713

Query: 997  QTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTK 1056
               +        +E +K   LL+Q+ +   A+ + I   ++    +    E ++     +
Sbjct: 714  LAHTQVERMSIKHEFDKDTELLQQQLKS--AMGEYIKKIEMKDFEIQGQAE-QINNLVIQ 770

Query: 1057 LENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISS 1116
            +   +EE+ + ++ + D       L  + + Q  QI  L E  L+   N  +   M+   
Sbjct: 771  MNTHQEEITKKNQIIEDLNNDISRLSNIQKSQLCQISILNEFCLSNNQN-EQILKMVPKR 829

Query: 1117 TIEPMSD-DANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKI 1175
             I  +    AN                +++  +E +++   L+ Q  + + + QE   +I
Sbjct: 830  LIYRLYKLQANQKFNLIFQEEINTYTQEIETLKENLKKEE-LKSQDLEESKKNQE--DQI 886

Query: 1176 IQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEI 1235
             Q E    EL        E++ +++ + E++NTE  NL     +L  SI    D++  E 
Sbjct: 887  KQQEQNIKEL-------HEKLKEIEKRQEEINTEIQNLKDEKEKLTQSIEE--DKKVIE- 936

Query: 1236 AELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQE--ETNKIVT--MEQ 1291
             EL K  ++Q++ + +    E++ Q    + K E+L   V   T E  + N ++    E+
Sbjct: 937  -ELNKS-ISQKDDELK----EIQQQCVNLKQKIEELEKDVSDKTSEINQLNDLIKNHQEK 990

Query: 1292 VTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXD 1351
            +   ++ LQ KE+ +   +E+    I  IE L  +  +                      
Sbjct: 991  IDQQEDSLQSKEKTIEETKEELKKKIEVIEKLHEQFNETNQTLGQRAQEIEQIIENKQQK 1050

Query: 1352 LRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLEL 1411
             +   +   ++ E+    I EE  ++ K +               +A  K+ E   Q E 
Sbjct: 1051 EKELQEKQNKIDEKQ--KIIEEKEEIIKENEQKLKQANEQLEENQNAINKLSEQQTQSEA 1108

Query: 1412 KDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRI--EDLTYEKESELAILRLKMHEN 1469
            +  ++ +K  +    L    +  +N +++L + ++ +  +   Y++E EL   + +   N
Sbjct: 1109 EIKQLQEKLKDTEELLASAKENLQNSQKELEQSQESLSQKQKLYDEEHELVQKKAEQITN 1168

Query: 1470 ANHYETMQKESEIERVK-----LIEELNVKITESV-SLNKQVAELNKALEEEVAKTNEMQ 1523
                E  +   ++E +K      IE  N    E + SLN+Q+ +  + + E   + +++ 
Sbjct: 1169 LEK-EISKLNEDLESLKQEHKSFIENTNKSHQEQIDSLNQQINQFKQNISENQKQIDQLN 1227

Query: 1524 TALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDA 1583
            +    +  +I   N+EI  L+  +   +  +      A + K     Q +N+   + +  
Sbjct: 1228 SESSQKSNQISDKNEEIQQLKGKIETLNEDLNSQKKTADELKIQLTAQQENSKEIKNMLQ 1287

Query: 1584 VPRAELDLAMYMLHQRD 1600
               ++ D  M  L+ +D
Sbjct: 1288 QTESQRDKLMDNLNSKD 1304



 Score = 84.2 bits (199), Expect = 3e-14
 Identities = 198/1160 (17%), Positives = 490/1160 (42%), Gaps = 80/1160 (6%)

Query: 51   QIKFERAQKCLENAALVSKRIKEHRKATAELLGRPFVP--GISESLANTLKQKEILMEKI 108
            Q K ++ +  L++     +  KE  K   E++ +        +++L    ++ E ++E  
Sbjct: 988  QEKIDQQEDSLQSKEKTIEETKEELKKKIEVIEKLHEQFNETNQTLGQRAQEIEQIIEN- 1046

Query: 109  KQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNALSVLQVKMKIM 168
            KQ KE   +     +                    +   +  ++E  NA++ L  +    
Sbjct: 1047 KQQKEKELQEKQNKIDEKQKIIEEKEEIIKENEQKLKQANEQLEENQNAINKLSEQQTQS 1106

Query: 169  ETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAM 228
            E  I  LQEK+ + ++++     A+                     KQ++   +   +  
Sbjct: 1107 EAEIKQLQEKLKDTEELL-----ASAKENLQNSQKELEQSQESLSQKQKLYDEEHELVQK 1161

Query: 229  EAEWKDEKQRLLKDIESKDVRISSLEEANK-LLEAARFEISLEHSKLAQELEQXXXXXXX 287
            +AE   +   L K+I   +  + SL++ +K  +E        +   L Q++ Q       
Sbjct: 1162 KAE---QITNLEKEISKLNEDLESLKQEHKSFIENTNKSHQEQIDSLNQQINQFKQNISE 1218

Query: 288  XXXXXXXLAKQSIEPS---CEEKTEIEE-KGSLEIANMTELTKKIELLEHLNCQI---RQ 340
                   L  +S + S    ++  EI++ KG +E  N  +L  + +  + L  Q+   ++
Sbjct: 1219 NQKQIDQLNSESSQKSNQISDKNEEIQQLKGKIETLN-EDLNSQKKTADELKIQLTAQQE 1277

Query: 341  TNKELENKL-ATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTD 399
             +KE++N L  T     K + + + K S          T   ++S   Q   +  +Q   
Sbjct: 1278 NSKEIKNMLQQTESQRDKLMDNLNSKDSQTAQLNQKLGT---LESQNEQQIKKISSQKEK 1334

Query: 400  KKINKNEIAKLEMVIQSLNKDLVD-KEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQ 458
             K  K  + +  + IQS+NK L   K+ +  E++             + L +++    Q 
Sbjct: 1335 IKQLKASLEQNNLEIQSINKQLEQTKQDLQKEQNKYENTSGQQSSTIEQLKSKIAELEQA 1394

Query: 459  HMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDE 518
              +    I   +  +  +++ K Q  +K++L  +     +K+   +LK+   +I +  +E
Sbjct: 1395 KSQNEQTI--SSEKQKNSQLEKDQNSIKEDL--QTLQQTLKEKQNELKNLSSEIEKFKEE 1450

Query: 519  IDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEK 578
              ++ + + ++  +++  L Q+          S+ N+ I   + EL    Q +++L E+ 
Sbjct: 1451 GKSSKQQIDELSKSNEENLSQINSLNIQIQVFSEQNETI---SAELTKKDQTISKLNEQN 1507

Query: 579  GNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAI-SLLESQKFDLVQELHILQQKY 637
               +   +D  + +M   +  ++M E +   E +++ + S ++  K  +  ++  +  K 
Sbjct: 1508 SQFE---IDIKTLQMKIREQSEQMNEEKEFQEKKIQQLNSTIDQLKLQIKSQVETINAK- 1563

Query: 638  DEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIK 697
              +++K+ +      +   ++ + + L++ ID   +    L   +E L     QL     
Sbjct: 1564 --LKEKIQESENAFDELDTTKTELLKLQDIIDGQRSQIITLQNELEKLNQLNSQLLEEKM 1621

Query: 698  DLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKI 757
              E+    I N+ +  I+ N ++   L++    K SE  A +  ++    Q Q     + 
Sbjct: 1622 KAESYHVKIQNQ-EEKIKSNAEMIQVLQEKL--KTSEQQANLLKQQLKNKQYQEDDQQRE 1678

Query: 758  QERDLYIENIESELSKYK--SRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSE 815
              + +     ++E++KY+  ++  + ++  A  + +  SL  +  QL   ++EKQ   S 
Sbjct: 1679 TRKSVSFLTSQAEMNKYQLDNQKQKWDQQEAEYKIKINSLNAQIQQL---IEEKQ---SN 1732

Query: 816  YTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQH 875
              +++  +  R +V++D ++ + + L ++  ++++ ++  +  + E + + ++++   + 
Sbjct: 1733 IDMKKSFMKERESVVVDKEKAL-RDLKQLYAQSRKNEESLEQKISEMEKVILNMNQEIES 1791

Query: 876  YNALVEKANRTDLAESESTKYQ-TQLRDLES-NL-KRITHEHQTLIVQKKKEIEDLEIEF 932
                + +AN+     + + KY+ +Q  DL S NL K +  E    +   +K+  ++  E 
Sbjct: 1792 LRTQLIRANQQIEQMAYARKYEASQYADLRSANLSKALQQESLPTLNNIQKQGSNMG-EL 1850

Query: 933  N-TQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDK 991
            N +QI  +   K   ++      +   ++ + +Q+   + +N   N+++   +  E+ + 
Sbjct: 1851 NLSQINHSFTQKDAEDDNI-MLADLANEILSLIQQ--GDQQNNEANLKQSASVGGEIANS 1907

Query: 992  HVQKQQTQSPDYTEQYINEINKLNALLKQK-DEEIIAL---NQKINNAQV-SYMSMVSDY 1046
               +  T +P+   Q ++ ++K+  ++ QK  ++++ L   N + N AQ+  ++ ++   
Sbjct: 1908 --SQFVTFTPEDENQILSSLSKIKNIIAQKLSQDLVNLQSKNSESNRAQLRKHLLIIIKV 1965

Query: 1047 ESKLAQF---TTKLENMEEEMQRVSKQL-LDSKQ-----HNEELQILVREQDDQIKELKE 1097
            ++ + Q+   T  ++N  +E+  +++Q  LD  +       +++ +  +  D+ I++   
Sbjct: 1966 QNIIHQWLYITFFIQNNIKELNNLNQQYGLDRWKKVRGGQADKINLQTKAIDEFIQQFSR 2025

Query: 1098 TKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVL 1157
              +T E    K      S T+   S  +                ++  E + F ++  + 
Sbjct: 2026 VLITLE---SKNNTSDSSFTVYAESTSSRQEFLKVKNSSRLDDLIRAMELQGFSEQ--LP 2080

Query: 1158 QEQSAKLNTELQECYTKIIQ 1177
              Q +K ++E+Q+    IIQ
Sbjct: 2081 NYQRSKTSSEIQQNLKGIIQ 2100


>UniRef50_UPI0000D8E0D4 Cluster: UPI0000D8E0D4 related cluster; n=1;
            Danio rerio|Rep: UPI0000D8E0D4 UniRef100 entry - Danio
            rerio
          Length = 2127

 Score =  184 bits (449), Expect = 1e-44
 Identities = 311/1608 (19%), Positives = 681/1608 (42%), Gaps = 120/1608 (7%)

Query: 49   ERQIKFERAQK-CLENAALVSKRIKEHRKATAELLGR--PFVPGISESLANTLKQKEILM 105
            +  +K  + QK  LE+    SK+IKE  +   + L +    +    E LA   K+   ++
Sbjct: 205  DEDLKMMKLQKQVLEDEK--SKKIKEEIQNERQNLEKMTEALKEEREDLAEETKKNNQVL 262

Query: 106  EKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNALSVLQVKM 165
            +++K    ++  S+   +                Q  DV +    ++ +++ L  LQ ++
Sbjct: 263  DEMK----VANESTLADILREKSNLEEMRENISKQTEDVENKKENLRLREDELRQLQAEI 318

Query: 166  KIMETTILDLQEKIN-EKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQEN 224
               +  I   +EKIN E ++    K+                     +D  +Q T M + 
Sbjct: 319  HKQQREIE--KEKINIESERAAIIKDVEDLQHKNLQQELEKEKEIIMKDRNKQQTNMNDI 376

Query: 225  FIAMEAEWK----------DEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKL 274
               M+ E K          ++KQ + K+ ++ D    SL+E  K ++  +     E +KL
Sbjct: 377  METMKNERKQLDKDKEEMEEQKQEMEKERDNMDQSRKSLDEDQKKMKLQKQMFEEEKNKL 436

Query: 275  AQ---ELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELL 331
             Q   ELE+                +Q +E   EE   ++ + S+    + E+ + I  L
Sbjct: 437  EQMKIELEREADEISKIKEETQN-KRQRLEKMTEELINLQREKSI----LEEMRENISKL 491

Query: 332  EHLNCQIRQTNKELENKLATMGTE-SKAVSSPSKKGSPLISRKSG-----RNTASKMKSP 385
            +      ++ +K  E++L  + TE  K  S    + + + S ++      +N  +++K  
Sbjct: 492  KEYIDNEKEKSKLREDELKKLQTEVQKQQSKIDMEKTNIESERAAMIREKQNMMTELKKK 551

Query: 386  WSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISE-KDTXXXXXXXXXXG 444
               +  +     T+K++  N+   L   +++L + L+D E      K             
Sbjct: 552  SEDVEIQMKEILTEKELLHNDRKLLTRDVENLQQKLIDLERDSKRLKLDREAFKEDLEKQ 611

Query: 445  KDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQL--KQELNDEIKDVNVKDLI 502
            K+  +A++Q E +   +    I     T +++EI   +EQ+  KQ+  D++K   +++L 
Sbjct: 612  KENTLAEIQKEREDVEKMNENI-----TREMHEIKHQEEQMNQKQDELDQLK-TEIQNLQ 665

Query: 503  EKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTE 562
            ++L+  +E I  + D      K+  +  +  + +L Q++  I N  +  +  KEI+    
Sbjct: 666  QELEKEKEII--MKDRKMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEIIMKAR 723

Query: 563  ELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQ 622
                L ++ +EL++++ N+   +++       + D  K+ +E E   E   +    +  Q
Sbjct: 724  S--QLDRRQSELDKQQTNMN-DIMETMKNERKQLDKDKEEME-EQKQEMEKEMKENISKQ 779

Query: 623  KFDLVQELHILQQKYDEVEDKLADISQLQSDQVC--SEIKSVHLEEQIDALSASKKEL-- 678
              D+ +E   ++ + DE+E   A+I + QS+     S I+    E + + L   K EL  
Sbjct: 780  TEDIEKEKDKIRLREDELEQLQAEIHKQQSETEIEKSNIEREAFENEKEELKQMKTELER 839

Query: 679  -ALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLA 737
             A  IE +KL+ +     ++++  D  + MN  +  + +N  + ++ +K   EK  + + 
Sbjct: 840  EADEIEKIKLETQHERQRVEEMTADFMETMNNERKQLDKNKVMIEE-QKQEMEKKRDDMD 898

Query: 738  KINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLER 797
            +        ++        ++E    +E ++  L +    I +++E     ++ R +LE+
Sbjct: 899  QSRKSLDEDLKMMKAQKQVLEEEKNKLEQMKIGLEREADEISKIKEE---TQNERQNLEK 955

Query: 798  KADQL---GSYLQEKQKAYSEYTIQEDELVNR--LAVLMDHDRVVEKQLLEIEHENKELQ 852
             A+ L     YL E+ K  ++  + + ++ N   LA L    R++E+    I  + ++++
Sbjct: 956  MANALKEEREYLAEEIKRKNQ-VLDKIKVANESTLADLQKEKRILEEMRENISKQIEDIE 1014

Query: 853  ---KKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKR 909
               +K+++  +E + LQ  +   Q+      E+    +    E    +   ++ ES L +
Sbjct: 1015 NEKEKSKLREDELKKLQTEVQKQQKRDTISKEERRTNERLNEEINIQKVNQQNRESELAK 1074

Query: 910  ----ITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLE-AQL 964
                I  + Q +  + K+EI     E   Q     ++K+ L + +  N++   + E  +L
Sbjct: 1075 LQEDILQQQQEMDEKTKEEINYDREEIYRQRTELNKEKETLKQMHTSNLKQPEKKEREEL 1134

Query: 965  QEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEE 1024
            ++ K+ I     +VE   ++   +ID  +QK + +    TE+ + +   L+    Q + +
Sbjct: 1135 EQLKDEINREKEDVEIRRELVEAVID--IQKYKEELQSVTEELLTKKRDLD----QLNSD 1188

Query: 1025 IIALNQKINNAQVSYMSMVSDYES---KLAQFTTKLENMEEEMQR---VSKQLLDSKQHN 1078
            +  L Q I    + +    ++ E    +L +    LE  ++E++    + +++ + K   
Sbjct: 1189 VQDLRQTIEEINIQHGKKRAELEGIGFELKKGEQLLEKQKDELKENGWIVEEIKNKKDSL 1248

Query: 1079 EELQI-LVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXX 1137
            E++ + ++R+ +D  KE  + KL  E+   + +   + ++I+ ++ +   +         
Sbjct: 1249 EKINMEILRKNEDMDKE--KGKLRSELQRQRED---LETSIQKLTHEKREIKNQIEQEKK 1303

Query: 1138 XXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQIN 1197
                +K   E +    R         L  E QE   +  +LE    +LT      +E+ N
Sbjct: 1304 DLQNMKSNLERQLESLRHEKANVEGLLEKEKQELKQEKKELEDQMMDLTREKQETEEERN 1363

Query: 1198 Q---LKSKLEQLNTE---NDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQ 1251
                LK++LE L  +   N+N    + + R  I     +   +  +L  + +A RE + +
Sbjct: 1364 NLMALKNQLEDLKEQIQNNENAKHLLEQERKDIDKQKQELQKQADDLDMRMIAHRE-NVE 1422

Query: 1252 KTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQE 1311
             ++  L  +    E K  ++L       +E+ + +    ++  LQN++Q++ + +  +  
Sbjct: 1423 MSKRSLDEEKKLLEQKANEILRQRDDLEKEKEDMMKKWNKLDVLQNEMQNENKAMEEI-- 1480

Query: 1312 KYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNIN 1371
            KY     +++  R+EI  E+                   DL  +N+S  Q + + I NIN
Sbjct: 1481 KY-----ELDGKRNEINKEQQRLEKEELDIERQKIADEQDLLIQNKSELQNENERIRNIN 1535

Query: 1372 EENAQLKKSSXXXXXXXXXXXXRVNDAEAKVL-----ELTHQLELKDSEIYQKTHEYTIT 1426
            E+   L++              R+++ +A+V      +LT Q E+K+++   +       
Sbjct: 1536 EQRDLLEQEKEDINHEWTQLQQRIDEFDAQVSKQKEEDLTKQKEMKENK--SELQNENER 1593

Query: 1427 LTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVK 1486
            +   N+  +  R+ L E E  +E     +E++  ++ +K        E ++KE E E  +
Sbjct: 1594 IRNLNEIIKKERETLKEMEAHLEKKKSLEETKANVIEMKTKAEP---EEIKKEKEKENEE 1650

Query: 1487 LIEELNVKITESVSLNKQVAELNKALEEEVAKTNE--MQTALENQEIEIVTLNDE-ITNL 1543
              EE   +  +   +  ++    + +EEE ++ +    QT LE  +IE     +E +T  
Sbjct: 1651 EEEEEEEEKEDLEKMKSEIMTQRQQMEEERSELDNKIKQTDLERHDIENSKQKEEDLTKQ 1710

Query: 1544 QNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDL 1591
            + M     S  +  +       +   E++     KE  + V RA++++
Sbjct: 1711 KKMEEERKSLEETKIKIIEMKTKTEPEKIKKEKEKE-EEEVMRAKVEI 1757



 Score =  165 bits (402), Expect = 7e-39
 Identities = 278/1503 (18%), Positives = 646/1503 (42%), Gaps = 127/1503 (8%)

Query: 152  KEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXX 211
            K+K+N L+ +Q + + +E    ++  +++E     E  N+                    
Sbjct: 610  KQKENTLAEIQKEREDVEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELE 669

Query: 212  EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISS-LEEANKLLEAARFEISLE 270
            ++ +  M   + + I  + E  ++KQ  L  ++++   +   LE+  +++  AR ++   
Sbjct: 670  KEKEIIMKDRKMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEIIMKARSQLDRR 729

Query: 271  HSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTE-LTK--- 326
             S+L ++                 L K   E   E+K E+E++    I+  TE + K   
Sbjct: 730  QSELDKQQTNMNDIMETMKNERKQLDKDKEEME-EQKQEMEKEMKENISKQTEDIEKEKD 788

Query: 327  KIEL----LEHLNCQIRQTNKELENKLATMGTES-KAVSSPSKKGSPLISRKSGRNTASK 381
            KI L    LE L  +I +   E E + + +  E+ +      K+    + R++      K
Sbjct: 789  KIRLREDELEQLQAEIHKQQSETEIEKSNIEREAFENEKEELKQMKTELEREADEIEKIK 848

Query: 382  MKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXX 441
            +++   +   E +  D  + +N NE  +L+      NK +++++    EK          
Sbjct: 849  LETQHERQRVEEMTADFMETMN-NERKQLDK-----NKVMIEEQKQEMEKKRDDMDQSRK 902

Query: 442  XXGKDTLIAQLQLEHQQHMEGP-SLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVN-VK 499
               +D  + + Q +  +  +     + +G   E  +EI+K++E+ + E  +  K  N +K
Sbjct: 903  SLDEDLKMMKAQKQVLEEEKNKLEQMKIGLERE-ADEISKIKEETQNERQNLEKMANALK 961

Query: 500  DLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVR 559
            +  E L    ++  Q+ D+I  AN++ +      K  L++M++ I    +  ++ KE  +
Sbjct: 962  EEREYLAEEIKRKNQVLDKIKVANESTLADLQKEKRILEEMRENISKQIEDIENEKEKSK 1021

Query: 560  LTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAE--TRLKAIS 617
            L E+   L +   E+++++    +   +  +   +  ++  + +  +N      +L+   
Sbjct: 1022 LRED--ELKKLQTEVQKQQKRDTISKEERRTNERLNEEINIQKVNQQNRESELAKLQEDI 1079

Query: 618  LLESQKFD--LVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASK 675
            L + Q+ D    +E++  +++      +L    +       S +K    +E+ + L   K
Sbjct: 1080 LQQQQEMDEKTKEEINYDREEIYRQRTELNKEKETLKQMHTSNLKQPEKKER-EELEQLK 1138

Query: 676  KELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISEL 735
             E+    E++++ +E +   I D++  KE++ +  +  + +  DL D+L     + + + 
Sbjct: 1139 DEINREKEDVEIRRELVEAVI-DIQKYKEELQSVTEELLTKKRDL-DQLNS-DVQDLRQT 1195

Query: 736  LAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSL 795
            + +IN +   K     GI  ++++ +  +E  + EL +    +  ++     +E     +
Sbjct: 1196 IEEINIQHGKKRAELEGIGFELKKGEQLLEKQKDELKENGWIVEEIKNKKDSLEKINMEI 1255

Query: 796  ERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKN 855
             RK + +    +EK K  SE   Q ++L   +  L    R ++ Q   IE E K+LQ   
Sbjct: 1256 LRKNEDMD---KEKGKLRSELQRQREDLETSIQKLTHEKREIKNQ---IEQEKKDLQNMK 1309

Query: 856  QILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQ 915
              L  + ++L+   ++++     L+EK  +    + E  + + Q+ DL    K+ T E +
Sbjct: 1310 SNLERQLESLRHEKANVE----GLLEKEKQE--LKQEKKELEDQMMDLTRE-KQETEEER 1362

Query: 916  TLIVQKKKEIEDL--EIEFNTQIESAI-RDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIE 972
              ++  K ++EDL  +I+ N   +  + +++K ++++ ++  +    L+ ++  ++ N+E
Sbjct: 1363 NNLMALKNQLEDLKEQIQNNENAKHLLEQERKDIDKQKQELQKQADDLDMRMIAHRENVE 1422

Query: 973  NLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQ-- 1030
                +++E  K+ LE     + +Q+       E  + + NKL+ L  +   E  A+ +  
Sbjct: 1423 MSKRSLDEEKKL-LEQKANEILRQRDDLEKEKEDMMKKWNKLDVLQNEMQNENKAMEEIK 1481

Query: 1031 --------KINNAQVSY--------MSMVSDYESKLAQFTTKLENMEEEMQRVSKQ--LL 1072
                    +IN  Q              ++D +  L Q  ++L+N  E ++ +++Q  LL
Sbjct: 1482 YELDGKRNEINKEQQRLEKEELDIERQKIADEQDLLIQNKSELQNENERIRNINEQRDLL 1541

Query: 1073 DSKQHN-----EELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANN 1127
            + ++ +      +LQ  + E D Q+ + KE  LT +  + + +     S ++  ++   N
Sbjct: 1542 EQEKEDINHEWTQLQQRIDEFDAQVSKQKEEDLTKQKEMKENK-----SELQNENERIRN 1596

Query: 1128 VDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTG 1187
            ++              ++E E  ++++  L+E  A +     E  TK  + E +  E   
Sbjct: 1597 LNEIIKKERET-----LKEMEAHLEKKKSLEETKANVI----EMKTKA-EPEEIKKEKEK 1646

Query: 1188 HDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQRE 1247
             +   +E+  + K  LE++ +E       + E RS + + + Q   E  ++  ++  Q+E
Sbjct: 1647 ENEEEEEEEEEEKEDLEKMKSEIMTQRQQMEEERSELDNKIKQTDLERHDI--ENSKQKE 1704

Query: 1248 ADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLR 1307
             D  K                ++ ++  + S +E   KI+ M+  T  +   ++KE+   
Sbjct: 1705 EDLTK----------------QKKMEEERKSLEETKIKIIEMKTKTEPEKIKKEKEKEEE 1748

Query: 1308 NLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQ-- 1365
             +     ++ +Q+E +RSEI+ E+                    +++E    +Q  E+  
Sbjct: 1749 EVMRAKVEIKSQLERVRSEIDHEQKKL-NDDKKMIEQEKEDLEKMKSEIMKQRQQMEEER 1807

Query: 1366 -----SILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLE-----LKDSE 1415
                  I   + E   ++ S             ++ +   ++ E+  +++     LK+ E
Sbjct: 1808 SELDNKIKQTDLERHDIENSKEIVQKLMVENKAKLQNENERIKEMDEEIKKEKETLKEME 1867

Query: 1416 IYQKTHE----YTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENAN 1471
             + +  +      I  TQR  + E++ +   +  K+ +DL  +++     L +++ E  +
Sbjct: 1868 AHLRKEKEEMRSVIEETQRRQK-EDLEKMSTDVNKQNQDLMNQRDLLKQKLMVEVEEQKH 1926

Query: 1472 HYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALE-NQE 1530
              +  ++E +IER K+ +E ++ I     L  +  E +  ++ ++ + NE +   E ++E
Sbjct: 1927 EIQFQKEELDIERQKIADEQDLLIQNKSELQNE-NEQDLLIQNKIEQQNENERIKEMDEE 1985

Query: 1531 I--EIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAE 1588
            I  E  TL +   NLQ       S I++      D ++G   +    + KE   ++P+ E
Sbjct: 1986 IKKERETLKEMEVNLQKEKEEIESVIEETQRRKEDLEKGETVEKHTDIIKEYTTSIPKEE 2045

Query: 1589 LDL 1591
             ++
Sbjct: 2046 YEI 2048



 Score =  165 bits (401), Expect = 9e-39
 Identities = 214/1110 (19%), Positives = 485/1110 (43%), Gaps = 84/1110 (7%)

Query: 503  EKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTE 562
            E L    ++  Q+ DE+  AN++ +      +  L++M++ I   ++  ++ KE +RL E
Sbjct: 7    EDLSEDAKRKNQVLDEMKVANESTLADILRERSNLQEMRENISKQTEDVENKKEKIRLRE 66

Query: 563  E-LHHLSQKV----AELEEEKGNLQLH---LVDYDSGRMIES-DVYKKMIEMENLAETRL 613
            E L  L  ++    +E E+EK N++     +++ D  R  ES  + ++  E E     ++
Sbjct: 67   EKLKQLQAEIHKQQSETEKEKSNIERERAAIINLD--RDAESLKLDREAFENEKEELKQM 124

Query: 614  KAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSA 673
            K     E++  D+  +   ++QK DE++    +I  LQ  Q   + K + ++++    + 
Sbjct: 125  KTELEREAEIHDIKHQEEQMKQKQDELDQLKTEIQNLQ--QELEKEKEIIMKDR----NK 178

Query: 674  SKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEK-- 731
             K+E     + ++ +K     + K L+ D +  M KLQ  + E+       E++  E+  
Sbjct: 179  DKEETEEQKQEMEKEKHDFDQSRKSLDEDLK--MMKLQKQVLEDEKSKKIKEEIQNERQN 236

Query: 732  ISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDR 791
            + ++   +  E +   +     +  + E  +  E+  +++ + KS +  + E+I+   + 
Sbjct: 237  LEKMTEALKEEREDLAEETKKNNQVLDEMKVANESTLADILREKSNLEEMRENISKQTE- 295

Query: 792  RYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHEN--K 849
               +E K + L     E ++  +E   Q+ E+      +      + K + +++H+N  +
Sbjct: 296  --DVENKKENLRLREDELRQLQAEIHKQQREIEKEKINIESERAAIIKDVEDLQHKNLQQ 353

Query: 850  ELQKKNQILLEENQNLQISLSD-MQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLK 908
            EL+K+ +I++++    Q +++D M+   N   +     +  E +  + + +  +++ + K
Sbjct: 354  ELEKEKEIIMKDRNKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKERDNMDQSRK 413

Query: 909  RITHEHQTLIVQK------KKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEA 962
             +  + + + +QK      K ++E ++IE   + +   + K+    K ++ +E +T+   
Sbjct: 414  SLDEDQKKMKLQKQMFEEEKNKLEQMKIELEREADEISKIKEETQNKRQR-LEKMTEELI 472

Query: 963  QLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKD 1022
             LQ  K+ +E +  N+ +L     E ID   +K + +         +E+ KL   ++++ 
Sbjct: 473  NLQREKSILEEMRENISKLK----EYIDNEKEKSKLRE--------DELKKLQTEVQKQQ 520

Query: 1023 EEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRV--SKQLL--DSKQHN 1078
             +I   + +  N +    +M+ + ++ + +   K E++E +M+ +   K+LL  D K   
Sbjct: 521  SKI---DMEKTNIESERAAMIREKQNMMTELKKKSEDVEIQMKEILTEKELLHNDRKLLT 577

Query: 1079 EELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXX 1138
             +++ L ++  D  ++ K  KL  E      E     +T+  +  +  +V+         
Sbjct: 578  RDVENLQQKLIDLERDSKRLKLDREAFKEDLEKQ-KENTLAEIQKEREDVEKMNENITRE 636

Query: 1139 XXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKI-IQLETLNTELTGHDVVNQ-EQI 1196
               +K QEE     + +  Q++  +L TE+Q    ++  + E +  +   H++ +Q EQ+
Sbjct: 637  MHEIKHQEE-----QMNQKQDELDQLKTEIQNLQQELEKEKEIIMKDRKMHEIKHQEEQM 691

Query: 1197 NQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHE 1256
            NQ + +L+QL TE  NL   + + +  I  A  Q     +EL KQ       D  +T   
Sbjct: 692  NQKQDELDQLKTEIQNLQQELEKEKEIIMKARSQLDRRQSELDKQQTNMN--DIMETMKN 749

Query: 1257 LRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADV 1316
             R QL   + + E+    ++   +E  +K    E +   ++K++ +E+ L  LQ +    
Sbjct: 750  ERKQLDKDKEEMEEQKQEMEKEMKENISK--QTEDIEKEKDKIRLREDELEQLQAEIHKQ 807

Query: 1317 INQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXD------LRT--ENQSYKQMQEQSIL 1368
             ++ EI +S IE E                    D      L T  E Q  ++M    + 
Sbjct: 808  QSETEIEKSNIEREAFENEKEELKQMKTELEREADEIEKIKLETQHERQRVEEMTADFME 867

Query: 1369 NINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDS------EIYQKTHE 1422
             +N E  QL K+             + +D +     L   L++  +      E   K  +
Sbjct: 868  TMNNERKQLDKNKVMIEEQKQEMEKKRDDMDQSRKSLDEDLKMMKAQKQVLEEEKNKLEQ 927

Query: 1423 YTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEI 1482
              I L +  DE   ++++     + +E +    + E   L  ++       + ++  +E 
Sbjct: 928  MKIGLEREADEISKIKEETQNERQNLEKMANALKEEREYLAEEIKRKNQVLDKIKVANES 987

Query: 1483 ERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITN 1542
                L +E  +      +++KQ+ ++    E+E +K  E +      E++     D I+ 
Sbjct: 988  TLADLQKEKRILEEMRENISKQIEDIEN--EKEKSKLREDELKKLQTEVQKQQKRDTISK 1045

Query: 1543 LQNMVRASSSKIQKHVSFASDTKQGRDEQL 1572
             +   R ++ ++ + ++     +Q R+ +L
Sbjct: 1046 EE---RRTNERLNEEINIQKVNQQNRESEL 1072



 Score =  159 bits (387), Expect = 4e-37
 Identities = 216/1147 (18%), Positives = 499/1147 (43%), Gaps = 98/1147 (8%)

Query: 461  EGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEID 520
            E  ++I++  + E +    +  E  K+EL     ++  +  I  +K  EEQ+ Q  DE+D
Sbjct: 93   ERAAIINLDRDAESLKLDREAFENEKEELKQMKTELEREAEIHDIKHQEEQMKQKQDELD 152

Query: 521  AANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGN 580
                 +  ++   + + + + K  +   + ++  K+   + +E H   Q    L+E+   
Sbjct: 153  QLKTEIQNLQQELEKEKEIIMKDRNKDKEETEEQKQ--EMEKEKHDFDQSRKSLDEDLKM 210

Query: 581  LQLHLVDYDSGRMIESDVYKKM-IEMENLAETRLKAISLLESQKFDLVQELHILQQKYDE 639
            ++L        +++E +  KK+  E++N  +   K    L+ ++ DL +E     Q  DE
Sbjct: 211  MKL------QKQVLEDEKSKKIKEEIQNERQNLEKMTEALKEEREDLAEETKKNNQVLDE 264

Query: 640  V----EDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGT 695
            +    E  LADI + +S+    E++  ++ +Q + +   K+ L L  + L+  + +++  
Sbjct: 265  MKVANESTLADILREKSN--LEEMRE-NISKQTEDVENKKENLRLREDELRQLQAEIHKQ 321

Query: 696  IKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKI-------- 747
             +++E +K +I ++    I++  DL  K  +   EK  E++ K  +++Q+ +        
Sbjct: 322  QREIEKEKINIESERAAIIKDVEDLQHKNLQQELEKEKEIIMKDRNKQQTNMNDIMETMK 381

Query: 748  --QTQFGIDAKIQER------------DLYIENIESELSKYKSRICRLEESIAVMEDRRY 793
              + Q   D +  E             D   ++++ +  K K +    EE    +E  + 
Sbjct: 382  NERKQLDKDKEEMEEQKQEMEKERDNMDQSRKSLDEDQKKMKLQKQMFEEEKNKLEQMKI 441

Query: 794  SLERKADQLGSYLQEKQKAYSEYTIQEDELVN---RLAVLMDHDRVVE--KQLLEIEHEN 848
             LER+AD++    +E Q          +EL+N     ++L +    +   K+ ++ E E 
Sbjct: 442  ELEREADEISKIKEETQNKRQRLEKMTEELINLQREKSILEEMRENISKLKEYIDNEKEK 501

Query: 849  KELQ----KKNQILLEENQN-LQISLSDMQQHYNALV-EKANRTDLAESESTKYQTQLRD 902
             +L+    KK Q  +++ Q+ + +  ++++    A++ EK N     + +S   + Q+++
Sbjct: 502  SKLREDELKKLQTEVQKQQSKIDMEKTNIESERAAMIREKQNMMTELKKKSEDVEIQMKE 561

Query: 903  LESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEA 962
            + +  K + H  + L+ +  + ++   I+     +    D++   E  EK  E      A
Sbjct: 562  ILTE-KELLHNDRKLLTRDVENLQQKLIDLERDSKRLKLDREAFKEDLEKQKENTL---A 617

Query: 963  QLQEYKNNIENLNMNV-EELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQK 1021
            ++Q+ + ++E +N N+  E++++      KH ++Q  Q  D  +Q   EI  L   L +K
Sbjct: 618  EIQKEREDVEKMNENITREMHEI------KHQEEQMNQKQDELDQLKTEIQNLQQEL-EK 670

Query: 1022 DEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEEL 1081
            ++EII  ++K++  +     M +  + +L Q  T+++N+++E+++  + ++ ++   +  
Sbjct: 671  EKEIIMKDRKMHEIKHQEEQM-NQKQDELDQLKTEIQNLQQELEKEKEIIMKARSQLDRR 729

Query: 1082 QILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXX 1141
            Q  + +Q   + ++ ET       + K +  +     E   +   N+             
Sbjct: 730  QSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKEMKENISKQTEDIEKEKDK 789

Query: 1142 LKVQEEEEFIQERSVLQEQS----AKLNTELQECYTKIIQLETLNTELTGHDVVNQEQIN 1197
            ++++E+E    +  + ++QS     K N E +    +  +L+ + TEL        ++I 
Sbjct: 790  IRLREDELEQLQAEIHKQQSETEIEKSNIEREAFENEKEELKQMKTELER----EADEIE 845

Query: 1198 QLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHEL 1257
            ++K + +      + + +   E  ++    +D+    I E  KQ + ++  D  ++   L
Sbjct: 846  KIKLETQHERQRVEEMTADFMETMNNERKQLDKNKVMIEE-QKQEMEKKRDDMDQSRKSL 904

Query: 1258 RVQLSAFESKYEQL------LDSVQSSTQEETNKIVTMEQVT--------SLQNKLQDKE 1303
               L   +++ + L      L+ ++   + E ++I  +++ T         + N L+++ 
Sbjct: 905  DEDLKMMKAQKQVLEEEKNKLEQMKIGLEREADEISKIKEETQNERQNLEKMANALKEER 964

Query: 1304 EHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQ 1363
            E+L    ++   V+++I++       +                    D+  E +  K ++
Sbjct: 965  EYLAEEIKRKNQVLDKIKVANESTLADLQKEKRILEEMRENISKQIEDIENEKEKSK-LR 1023

Query: 1364 EQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEY 1423
            E  +  +  E  Q ++              R+N+ E  + ++  Q   ++SE+  K  E 
Sbjct: 1024 EDELKKLQTE-VQKQQKRDTISKEERRTNERLNE-EINIQKVNQQ--NRESEL-AKLQED 1078

Query: 1424 TITLTQRNDE--FENVRQQLVEYEKRIEDLTYEKES--ELAILRLKMHENANHYETMQKE 1479
             +   Q  DE   E +     E  ++  +L  EKE+  ++    LK  E     E  Q +
Sbjct: 1079 ILQQQQEMDEKTKEEINYDREEIYRQRTELNKEKETLKQMHTSNLKQPEKKEREELEQLK 1138

Query: 1480 SEIERVKLIEELNVKITESV-SLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLND 1538
             EI R K   E+  ++ E+V  + K   EL    EE + K  ++     N +++ +    
Sbjct: 1139 DEINREKEDVEIRRELVEAVIDIQKYKEELQSVTEELLTKKRDLDQL--NSDVQDLRQTI 1196

Query: 1539 EITNLQN 1545
            E  N+Q+
Sbjct: 1197 EEINIQH 1203



 Score =  142 bits (344), Expect = 7e-32
 Identities = 230/1174 (19%), Positives = 521/1174 (44%), Gaps = 96/1174 (8%)

Query: 215  KQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKL 274
            K++    ++N   M    K+E++ L ++I+ K+  +  ++ AN   E+   ++  E  ++
Sbjct: 943  KEETQNERQNLEKMANALKEEREYLAEEIKRKNQVLDKIKVAN---ESTLADLQKE-KRI 998

Query: 275  AQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHL 334
             +E+ +               +K   +   + +TE++++   +  +  E      L E +
Sbjct: 999  LEEMRENISKQIEDIENEKEKSKLREDELKKLQTEVQKQQKRDTISKEERRTNERLNEEI 1058

Query: 335  NCQ-IRQTNKELE-NKLATMGTESKAVSSPSKKGSPLISRKS---GRNTASKMKSPWSQL 389
            N Q + Q N+E E  KL     + +       K      R+     R   +K K    Q+
Sbjct: 1059 NIQKVNQQNRESELAKLQEDILQQQQEMDEKTKEEINYDREEIYRQRTELNKEKETLKQM 1118

Query: 390  SSETLNQDTDKKINKNEIAKLEMVIQS----LNKDLVDKEYVISEKDTXXXXXXXXXXGK 445
             +  L Q   K+  + E  K E+  +     + ++LV+    I +              K
Sbjct: 1119 HTSNLKQPEKKEREELEQLKDEINREKEDVEIRRELVEAVIDIQKYKEELQSVTEELLTK 1178

Query: 446  DTLIAQLQLEHQ---QHMEGPSLIHVGTNTEDVNEIA---KVQEQLKQELNDEIKDVNVK 499
               + QL  + Q   Q +E  ++ H G    ++  I    K  EQL ++  DE+K+    
Sbjct: 1179 KRDLDQLNSDVQDLRQTIEEINIQH-GKKRAELEGIGFELKKGEQLLEKQKDELKENGW- 1236

Query: 500  DLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTID-NFSKVSDSNKEIV 558
             ++E++K+ ++ + ++N EI   N++M K K   + +L++ ++ ++ +  K++   +EI 
Sbjct: 1237 -IVEEIKNKKDSLEKINMEILRKNEDMDKEKGKLRSELQRQREDLETSIQKLTHEKREIK 1295

Query: 559  RLTEE--------LHHLSQKVAELEEEKGNLQ-LHLVDYDSGRMIESDVYKKMIEM---E 606
               E+          +L +++  L  EK N++ L   +    +  + ++  +M+++   +
Sbjct: 1296 NQIEQEKKDLQNMKSNLERQLESLRHEKANVEGLLEKEKQELKQEKKELEDQMMDLTREK 1355

Query: 607  NLAETRLKAISLLESQKFDLVQEL-------HILQQKYDEVEDKLADISQLQSDQVCSEI 659
               E     +  L++Q  DL +++       H+L+Q+  +++ +  ++ Q Q+D +  ++
Sbjct: 1356 QETEEERNNLMALKNQLEDLKEQIQNNENAKHLLEQERKDIDKQKQEL-QKQADDL--DM 1412

Query: 660  KSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQ--NYIQEN 717
            + +   E ++    SK+ L    + L+    ++     DLE +KED+M K    + +Q  
Sbjct: 1413 RMIAHRENVEM---SKRSLDEEKKLLEQKANEILRQRDDLEKEKEDMMKKWNKLDVLQNE 1469

Query: 718  MDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAK--IQERDLYIENIESELSKYK 775
            M   +K  +    ++     +IN E+Q   + +  I+ +    E+DL I+N +SEL    
Sbjct: 1470 MQNENKAMEEIKYELDGKRNEINKEQQRLEKEELDIERQKIADEQDLLIQN-KSELQNEN 1528

Query: 776  SRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDR 835
             RI  + E   ++E  +  +  +  QL   + E     S+   Q++E + +   + ++  
Sbjct: 1529 ERIRNINEQRDLLEQEKEDINHEWTQLQQRIDEFDAQVSK---QKEEDLTKQKEMKENKS 1585

Query: 836  VVEKQLLEIEHENKELQKKNQILLEENQNLQI--SLSDMQQHYNALVEKANRTDLAESES 893
             ++ +   I + N+ ++K+ + L E   +L+   SL + + +   +  KA   ++ + E 
Sbjct: 1586 ELQNENERIRNLNEIIKKERETLKEMEAHLEKKKSLEETKANVIEMKTKAEPEEI-KKEK 1644

Query: 894  TKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKN 953
             K   +  + E   K    + ++ I+ +++++E+   E + +I+    ++  +    +K 
Sbjct: 1645 EKENEEEEEEEEEEKEDLEKMKSEIMTQRQQMEEERSELDNKIKQTDLERHDIENSKQKE 1704

Query: 954  IEYVTQLEAQ-----LQEYKNNIENLNMNVE-ELNKMNLELIDKHVQKQQTQSPDYTEQY 1007
             +   Q + +     L+E K  I  +    E E  K   E  ++ V + + +     E+ 
Sbjct: 1705 EDLTKQKKMEEERKSLEETKIKIIEMKTKTEPEKIKKEKEKEEEEVMRAKVEIKSQLERV 1764

Query: 1008 INEIN----KLN---ALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENM 1060
             +EI+    KLN    +++Q+ E++  +  +I   +       S+ ++K+ Q   +  ++
Sbjct: 1765 RSEIDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDNKIKQTDLERHDI 1824

Query: 1061 EEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEP 1120
            E   + V K ++++K   +     ++E D++IK+ KET    E ++ K +  + S   E 
Sbjct: 1825 ENSKEIVQKLMVENKAKLQNENERIKEMDEEIKKEKETLKEMEAHLRKEKEEMRSVIEET 1884

Query: 1121 MSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKI-IQLE 1179
                  +++               ++ ++ + +R +L++   KL  E++E   +I  Q E
Sbjct: 1885 QRRQKEDLEKMSTDVN--------KQNQDLMNQRDLLKQ---KLMVEVEEQKHEIQFQKE 1933

Query: 1180 TLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELW 1239
             L+ E        Q+ + Q KS+L+  N E D L+    E ++  +  + +   EI +  
Sbjct: 1934 ELDIE-RQKIADEQDLLIQNKSELQNEN-EQDLLIQNKIEQQNE-NERIKEMDEEIKK-E 1989

Query: 1240 KQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKL 1299
            ++ L + E + QK + E+    S  E    +  D  +  T E+   I+  E  TS+  + 
Sbjct: 1990 RETLKEMEVNLQKEKEEIE---SVIEETQRRKEDLEKGETVEKHTDII-KEYTTSIPKEE 2045

Query: 1300 QDKEEHLRN----LQEKYADVINQIEILRSEIED 1329
             + E   RN    LQ++   V   +E ++++ E+
Sbjct: 2046 YEIERAARNRETILQKREEIVKRHMEEIQNQREE 2079



 Score = 93.9 bits (223), Expect = 3e-17
 Identities = 147/739 (19%), Positives = 322/739 (43%), Gaps = 54/739 (7%)

Query: 843  EIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRD 902
            E E  +++ ++KNQ+L E     + +L+D+ +  + L E          +    + ++R 
Sbjct: 5    EREDLSEDAKRKNQVLDEMKVANESTLADILRERSNLQEMRENISKQTEDVENKKEKIRL 64

Query: 903  LESNLKRI---THEHQTLIVQKKKEIEDLE---IEFNTQIESAIRDKKVL-NEKYE-KNI 954
             E  LK++    H+ Q+   ++K  IE      I  +   ES   D++   NEK E K +
Sbjct: 65   REEKLKQLQAEIHKQQSETEKEKSNIERERAAIINLDRDAESLKLDREAFENEKEELKQM 124

Query: 955  EYVTQLEAQLQEYKNNIENLNMNVEELNKMNLEL------IDKH---VQKQQTQSPDYTE 1005
            +   + EA++ + K+  E +    +EL+++  E+      ++K    + K + +  + TE
Sbjct: 125  KTELEREAEIHDIKHQEEQMKQKQDELDQLKTEIQNLQQELEKEKEIIMKDRNKDKEETE 184

Query: 1006 QYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQ 1065
            +   E+ K        D+   +L++ +   ++    ++ D +SK  +     E ++ E Q
Sbjct: 185  EQKQEMEKEK---HDFDQSRKSLDEDLKMMKLQ-KQVLEDEKSKKIK-----EEIQNERQ 235

Query: 1066 RVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDA 1125
             + K     K+  E+L    ++ +  + E+K    +   +I + E   +    E +S   
Sbjct: 236  NLEKMTEALKEEREDLAEETKKNNQVLDEMKVANESTLADILR-EKSNLEEMRENISKQT 294

Query: 1126 NNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTEL 1185
             +V+            L+  + E   Q+R + +E   K+N E  E    I  +E L  + 
Sbjct: 295  EDVENKKENLRLREDELRQLQAEIHKQQREIEKE---KINIE-SERAAIIKDVEDLQHKN 350

Query: 1186 TGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQ--HL 1243
               ++  +++I  +K + +Q    ND ++ T+   R  +    ++   +  E+ K+  ++
Sbjct: 351  LQQELEKEKEI-IMKDRNKQQTNMND-IMETMKNERKQLDKDKEEMEEQKQEMEKERDNM 408

Query: 1244 AQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTM-EQVTSLQNKLQDK 1302
             Q      + + ++++Q   FE + +  L+ ++   + E ++I  + E+  + + +L+  
Sbjct: 409  DQSRKSLDEDQKKMKLQKQMFEEE-KNKLEQMKIELEREADEISKIKEETQNKRQRLEKM 467

Query: 1303 EEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQM 1362
             E L NLQ +     + +E +R  I   K  +                 L+TE Q  +  
Sbjct: 468  TEELINLQREK----SILEEMRENISKLK-EYIDNEKEKSKLREDELKKLQTEVQKQQSK 522

Query: 1363 QEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHE 1422
             +    NI  E A + +              +  D E ++ E+  + EL  ++    T +
Sbjct: 523  IDMEKTNIESERAAMIREK---QNMMTELKKKSEDVEIQMKEILTEKELLHNDRKLLTRD 579

Query: 1423 YTITLTQRNDEFENVRQQL-VEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKE-S 1480
                L Q+  + E   ++L ++ E   EDL  +KE+ LA ++ +  +     E + +E  
Sbjct: 580  VE-NLQQKLIDLERDSKRLKLDREAFKEDLEKQKENTLAEIQKEREDVEKMNENITREMH 638

Query: 1481 EIERVKLIEELNVKITESVSLNKQVAELNKALEEE---VAKTNEMQTALENQEIEIVTLN 1537
            EI+  +  E++N K  E   L  ++  L + LE+E   + K  +M   +++QE ++    
Sbjct: 639  EIKHQE--EQMNQKQDELDQLKTEIQNLQQELEKEKEIIMKDRKMH-EIKHQEEQMNQKQ 695

Query: 1538 DEITNLQNMVRASSSKIQK 1556
            DE+  L+  ++    +++K
Sbjct: 696  DELDQLKTEIQNLQQELEK 714



 Score = 90.2 bits (214), Expect = 4e-16
 Identities = 140/719 (19%), Positives = 322/719 (44%), Gaps = 59/719 (8%)

Query: 212  EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271
            ++ K+ + +     +    + + EK+ ++K     DV  + ++  NK +E  ++E+  + 
Sbjct: 1429 DEEKKLLEQKANEILRQRDDLEKEKEDMMKKWNKLDVLQNEMQNENKAMEEIKYELDGKR 1488

Query: 272  SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTE----LTKK 327
            +++ +E +Q                +Q +    + K+E++ +    I N+ E    L ++
Sbjct: 1489 NEINKE-QQRLEKEELDIERQKIADEQDL--LIQNKSELQNENE-RIRNINEQRDLLEQE 1544

Query: 328  IELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGR--NTASKMKSP 385
             E + H   Q++Q   E + +++    E        K+    +  ++ R  N    +K  
Sbjct: 1545 KEDINHEWTQLQQRIDEFDAQVSKQKEEDLTKQKEMKENKSELQNENERIRNLNEIIKKE 1604

Query: 386  WSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLV---DKEYVISEKDTXXXXXXXXX 442
               L     + +  K + + +   +EM  ++  +++    +KE    E++          
Sbjct: 1605 RETLKEMEAHLEKKKSLEETKANVIEMKTKAEPEEIKKEKEKENEEEEEEEEEEKEDLEK 1664

Query: 443  XGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQL-KQELNDE----IKDVN 497
               + +  + Q+E ++      +        D+    + +E L KQ+  +E    +++  
Sbjct: 1665 MKSEIMTQRQQMEEERSELDNKIKQTDLERHDIENSKQKEEDLTKQKKMEEERKSLEETK 1724

Query: 498  VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSK-VSDSNKE 556
            +K +  K K+  E+I +   E +   + +++ K   K +L++++  ID+  K ++D  K 
Sbjct: 1725 IKIIEMKTKTEPEKIKK---EKEKEEEEVMRAKVEIKSQLERVRSEIDHEQKKLNDDKKM 1781

Query: 557  IVRLTEELHHLSQKVA----ELEEEKGNLQLHLVDYDSGRM-IESD---VYKKMIE---- 604
            I +  E+L  +  ++     ++EEE+  L   +   D  R  IE+    V K M+E    
Sbjct: 1782 IEQEKEDLEKMKSEIMKQRQQMEEERSELDNKIKQTDLERHDIENSKEIVQKLMVENKAK 1841

Query: 605  MENLAETRLKAISLLESQKFDLVQ-ELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVH 663
            ++N  E   +    ++ +K  L + E H+ ++K +E+   + +  + Q + +      V+
Sbjct: 1842 LQNENERIKEMDEEIKKEKETLKEMEAHLRKEK-EEMRSVIEETQRRQKEDLEKMSTDVN 1900

Query: 664  LEEQ--IDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLT 721
             + Q  ++     K++L + +E     K ++    ++L+ +++ I ++    IQ   +L 
Sbjct: 1901 KQNQDLMNQRDLLKQKLMVEVEE---QKHEIQFQKEELDIERQKIADEQDLLIQNKSELQ 1957

Query: 722  DKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRI-CR 780
            ++ E+       +LL +   E+Q++ +    +D +I++    ++ +E  L K K  I   
Sbjct: 1958 NENEQ-------DLLIQNKIEQQNENERIKEMDEEIKKERETLKEMEVNLQKEKEEIESV 2010

Query: 781  LEESIAVMED--RRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVE 838
            +EE+    ED  +  ++E+  D +  Y     K   EY I E    NR  +L   + +V+
Sbjct: 2011 IEETQRRKEDLEKGETVEKHTDIIKEYTTSIPK--EEYEI-ERAARNRETILQKREEIVK 2067

Query: 839  KQLLEIEHENKELQKK-NQILLEENQN---LQISLSDMQQHYNALVEKANRTDL-AESE 892
            + + EI+++ +ELQKK  Q L +E +N   L I     ++  + L+E+  R +  AE+E
Sbjct: 2068 RHMEEIQNQREELQKKMMQDLQKERENVNALVIQHQKEREQRDILIEENKRKEKHAEAE 2126



 Score = 83.8 bits (198), Expect = 4e-14
 Identities = 171/861 (19%), Positives = 360/861 (41%), Gaps = 66/861 (7%)

Query: 152  KEKDNALSVLQVKMKIMETTILDL-QEKINEKDQIIEAKN----------KATTXXXXXX 200
            KEK    S LQ + + +ET+I  L  EK   K+QI + K           +         
Sbjct: 1264 KEKGKLRSELQRQREDLETSIQKLTHEKREIKNQIEQEKKDLQNMKSNLERQLESLRHEK 1323

Query: 201  XXXXXXXXXXXEDTKQQMTKMQENFIAM---EAEWKDEKQRLL---KDIESKDVRISSLE 254
                       ++ KQ+  ++++  + +   + E ++E+  L+     +E    +I + E
Sbjct: 1324 ANVEGLLEKEKQELKQEKKELEDQMMDLTREKQETEEERNNLMALKNQLEDLKEQIQNNE 1383

Query: 255  EANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKG 314
             A  LLE  R +I  +  +L ++ +               ++K+S++   EEK  +E+K 
Sbjct: 1384 NAKHLLEQERKDIDKQKQELQKQADDLDMRMIAHRENVE-MSKRSLD---EEKKLLEQKA 1439

Query: 315  SLEIANMTELTK-KIELLEHLN-CQIRQTNKELENK-LATMGTESKAVSSPSKKGSPLIS 371
            +  +    +L K K ++++  N   + Q   + ENK +  +  E     +   K    + 
Sbjct: 1440 NEILRQRDDLEKEKEDMMKKWNKLDVLQNEMQNENKAMEEIKYELDGKRNEINKEQQRLE 1499

Query: 372  RKSGRNTASKMKSPWSQL--SSETLNQDTDKKINKNEIAKL-EMVIQSLNKDLVDKEYVI 428
            ++       K+      L  +   L  + ++  N NE   L E   + +N +    +  I
Sbjct: 1500 KEELDIERQKIADEQDLLIQNKSELQNENERIRNINEQRDLLEQEKEDINHEWTQLQQRI 1559

Query: 429  SEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIH--VGTNTEDVNEIAKVQEQLK 486
             E D            K   + + + E Q   E    ++  +    E + E+    E+ K
Sbjct: 1560 DEFDAQVSKQKEEDLTKQKEMKENKSELQNENERIRNLNEIIKKERETLKEMEAHLEKKK 1619

Query: 487  --QELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANK-NMIKVKSNHKLKLKQMQKT 543
              +E    + ++  K   E++K  +E+  +  +E +   K ++ K+KS    + +QM++ 
Sbjct: 1620 SLEETKANVIEMKTKAEPEEIKKEKEKENEEEEEEEEEEKEDLEKMKSEIMTQRQQMEEE 1679

Query: 544  ---IDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQ---LHLVDYDSGRMIESD 597
               +DN  K +D  +  +  +++      K  ++EEE+ +L+   + +++  +    E  
Sbjct: 1680 RSELDNKIKQTDLERHDIENSKQKEEDLTKQKKMEEERKSLEETKIKIIEMKTKTEPEKI 1739

Query: 598  VYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCS 657
              +K  E E +   +++  S LE  + ++  E   L      +E +  D+ +++S+ +  
Sbjct: 1740 KKEKEKEEEEVMRAKVEIKSQLERVRSEIDHEQKKLNDDKKMIEQEKEDLEKMKSEIMKQ 1799

Query: 658  EIKSVHLEEQIDALSASKKELALV---IENLKLDKEQLYGTIK-DLENDKEDIMNKLQNY 713
              +   +EE+   L    K+  L    IEN K   ++L    K  L+N+ E I    +  
Sbjct: 1800 RQQ---MEEERSELDNKIKQTDLERHDIENSKEIVQKLMVENKAKLQNENERIKEMDEEI 1856

Query: 714  IQENMDLTD-----KLEKMSAEKISELLAKINHEEQSKIQTQFGIDAK--IQERDLYIEN 766
             +E   L +     + EK     + E   +   E+  K+ T      +  + +RDL  + 
Sbjct: 1857 KKEKETLKEMEAHLRKEKEEMRSVIEETQRRQKEDLEKMSTDVNKQNQDLMNQRDLLKQK 1916

Query: 767  IESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELV-N 825
            +  E+ + K  I   +E + +        ++ AD+    +Q K +  +E   ++D L+ N
Sbjct: 1917 LMVEVEEQKHEIQFQKEELDIER------QKIADEQDLLIQNKSELQNEN--EQDLLIQN 1968

Query: 826  RLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANR 885
            ++    +++R+ E    EI+ E + L++    L +E + ++  + + Q+    L EK   
Sbjct: 1969 KIEQQNENERIKEMDE-EIKKERETLKEMEVNLQKEKEEIESVIEETQRRKEDL-EKGET 2026

Query: 886  TDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKV 945
             +       +Y T +   E  ++R     +T I+QK++EI    +E   Q +     KK+
Sbjct: 2027 VEKHTDIIKEYTTSIPKEEYEIERAARNRET-ILQKREEIVKRHME-EIQNQREELQKKM 2084

Query: 946  LNEKYEKNIEYVTQLEAQLQE 966
            + +  +K  E V  L  Q Q+
Sbjct: 2085 MQD-LQKERENVNALVIQHQK 2104


>UniRef50_A2FQ07 Cluster: Viral A-type inclusion protein, putative;
            n=1; Trichomonas vaginalis G3|Rep: Viral A-type inclusion
            protein, putative - Trichomonas vaginalis G3
          Length = 2366

 Score =  184 bits (447), Expect = 2e-44
 Identities = 308/1509 (20%), Positives = 627/1509 (41%), Gaps = 152/1509 (10%)

Query: 140  QLGDVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXX 199
            ++ D+      +++K+N L     + K +E      + + N+    ++ KNKA +     
Sbjct: 905  KINDLMAQIKALQQKNNELDK---ENKELEAAKEASENENNDLKNDLQTKNKALSKAERD 961

Query: 200  XXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKL 259
                        E  K+++  +++    ++A   ++   L K+    +  +++ ++  K 
Sbjct: 962  NDKLQNANKALDE-AKEKIKALEDEVSDLKALVSEKDGDLQKEKRENERLVANKDQLTKN 1020

Query: 260  LEAARFEI---SLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSL 316
             E    ++   + E  KL  +++               L K + E   E+  E + K   
Sbjct: 1021 NEELYDQLKNETTEKIKLDGQVKNAERDLAKANATNEELTKSN-EHLQEQNDEKDAKIKE 1079

Query: 317  EIANMTELTKKIELLEHLNCQI---RQTNKELENKLATMGTESKAVSSPSKKGSPLISRK 373
              A + EL KK+  L  L  +I   ++TN EL+N +  +    KA      K + L  + 
Sbjct: 1080 LQAKLNELEKKLSELPGLQDEIAKQKETNNELQNNVNDL---EKAGKDKDNKINELQKKA 1136

Query: 374  SG-RNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVD----KEYVI 428
            +   NT   ++   ++L  E   +D D   NKN    LE  I+ L K + D    K  + 
Sbjct: 1137 NELENTKKDLEDVTNEL--ENTQKDLDNSNNKNR--DLEKQIKDLKKQIEDLNREKNDLK 1192

Query: 429  SEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQE 488
             + DT           +D ++  L+ +  +       +    N  +  E+A  + +L + 
Sbjct: 1193 DQLDTSKLAGDELSK-RDEVLDNLRKQIAELAAKNKDLENKANDNNAEELAAKEAEL-EN 1250

Query: 489  LNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQ-KTIDNF 547
            +N +++    K+L E+    EE     N+ +    +N    + N +LK +Q   K ++  
Sbjct: 1251 INKQLEQTK-KELAER---DEELKNAKNENLAKEKENQKLNRENERLKFEQQDLKDLEEE 1306

Query: 548  SK-VSDSN----KEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYD------SGRMIES 596
            +K + D N     ++  L  +L    +    L+     LQ ++ D D      S   I+ 
Sbjct: 1307 NKNLDDENAALKSKVNALENDLQKAKRDADRLKLNNDQLQTNIDDLDNKLKEESAEKIKL 1366

Query: 597  DVYKKMIEME-----NLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQ 651
            D   K  + E        E   KA   L+ Q  D   +L  +Q K +E++ K  D  ++Q
Sbjct: 1367 DAQAKAADRELQSAKAATEEEKKANDQLQGQIKDKDNKLKEMQAKLNEMQKKANDADRIQ 1426

Query: 652  SDQVCSEIKSV--HLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNK 709
            +  + + +KS      +  +       EL   +   +    QL  T ++LE+ + D+ N+
Sbjct: 1427 N--LANSLKSQLDDANKSNNEKDNQLNELQKKLNEAQKKANQLEPTKQELEDARNDL-NE 1483

Query: 710  LQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQS---KIQTQFGIDAKIQERDLYIEN 766
             Q  +  + +    LEK   + + + +  +N+E+Q+    + T    D ++ +RD  + N
Sbjct: 1484 KQKELDASNNKNRDLEKQIKD-LKKQIGDLNNEKQALKDDLDTSKLADDELSKRDEVLGN 1542

Query: 767  IESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNR 826
            ++ +L+   ++   LE    V  D    L  K  +L +   + ++   +    EDEL N 
Sbjct: 1543 LKKQLADQLAKNKELEAK--VKGDNGDELAAKDAELDALKDQLEQVKKDLAETEDELKNA 1600

Query: 827  LAVLMDHDRVVEKQLLEIEH---ENKELQKKNQILLE---ENQNLQISLSDMQQHYNALV 880
                   D+ ++K   ++EH      +L+K N+ +     EN  L+  L++ +       
Sbjct: 1601 RNESSAKDKEIQKLARDLEHLKDAEDDLEKANEEIKNRDAENNELKGQLANKENELQKSK 1660

Query: 881  EKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAI 940
            ++ +R  L++ + +K+     DL + L   T ++  L  Q    +++LE    T      
Sbjct: 1661 QENDRLQLSKDQLSKHND---DLNNQLTAATTDNIKLDAQ----VKELERRLGTN----- 1708

Query: 941  RDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQS 1000
                  N   E+  + + QL+++  +  N I++L+   +++N +  +  D    +QQ   
Sbjct: 1709 ------NAAQEQQAQTIEQLKSEAADKDNKIKDLH---DQINNLQKKANDADNLQQQL-- 1757

Query: 1001 PDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENM 1060
             DY +  ++E NK N     KD ++  L +K N +Q           ++L     +LE+ 
Sbjct: 1758 -DYAKSQLDEANKSN---NDKDNQLNELQKKFNESQKK--------ANQLEPTKQELEDS 1805

Query: 1061 EEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIP---KTEGMI---- 1113
              ++    K+L +S   N +L+  ++E   QI++LK+ K   +  +    K + +I    
Sbjct: 1806 RNDLNEKQKELDESNNKNRDLEKQIKELKKQIEDLKKQKDDLQEQLDNNVKADDVIDKLR 1865

Query: 1114 --ISSTIEPMSD-DANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQE 1170
              I+  +  + + +A N D            ++   + +F Q +  L E+  +L      
Sbjct: 1866 KQIAELLAKVKELEAKNKDNTGDELAVKDAEIE-SLKNQFEQAKKDLDEKELELKQTSDN 1924

Query: 1171 CYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQ 1230
              +K  +L+  N EL     V+QE + Q   + ++L+ EN  L + +A   + +  +   
Sbjct: 1925 LSSKDKELQKANRELERLQDVDQE-LAQANEENKKLDAENGELKTQLANTENELQKSKQD 1983

Query: 1231 RGFEIAELWKQHLAQREADFQKT---EHELRVQLSAFESKYEQLLDSVQSSTQEETNKIV 1287
               E  +     L +   D  K    E    ++L+    + ++ L +  ++  ++   I 
Sbjct: 1984 N--ERLQSSNDQLTKNTDDLNKKLTDETTDNIKLNGLIQELQRRLANNDAAIAQQAESID 2041

Query: 1288 TM-EQVTSLQNKLQDKEEHLRNLQEKYADVIN---QIEILRSEIEDEKVAFXXXXXXXXX 1343
             + EQ     NK++D  + + NLQ+K  D  N   Q++  +S++++   +          
Sbjct: 2042 KLNEQAADKDNKIKDLHDQINNLQKKANDADNLQQQLDYAKSQLDEANKSNNDKDNQLNE 2101

Query: 1344 XXXXXXXDLRTENQ--SYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAK 1401
                     +  NQ    KQ  E S  ++NE+  +L +S+            +  D E +
Sbjct: 2102 LQKKFNESQKKANQLEPTKQELEDSRNDLNEKQKELDESNN-----------KNRDLEKQ 2150

Query: 1402 VLELTHQLELKDSE---IYQKTHEYTIT---LTQRNDEFENVRQQLVEYEKRIEDLTYEK 1455
            + EL  Q+   DSE   +  K  +  +    +++R++  +N+R+Q+ E   + +DL    
Sbjct: 2151 IKELKKQIGNLDSEKQALQDKLDDIKLADDAISKRDEVLDNLRKQIAELAAKNKDLEN-- 2208

Query: 1456 ESELAILRLKMHENANHYETMQKESEIERV-KLIEELNVKITESVSLNKQVAELNKALEE 1514
                     K ++N N  E   KE+E+E + K +E+   ++ E     K     N A E+
Sbjct: 2209 ---------KANDN-NAEELAAKEAELENINKQLEQTKKELAERDEELKNAKNENLAKEK 2258

Query: 1515 EVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDE-QLD 1573
            E  K N     L+ ++ ++  L +E  NL +   A  SK+    +     K+  D  +L+
Sbjct: 2259 ENQKLNRENERLKFEQQDLKDLEEENKNLDDENAALKSKVNALENDLQKAKRDADRLKLN 2318

Query: 1574 NTMNKELLD 1582
            N   +  +D
Sbjct: 2319 NDQLQTNID 2327



 Score =  171 bits (415), Expect = 2e-40
 Identities = 301/1479 (20%), Positives = 638/1479 (43%), Gaps = 148/1479 (10%)

Query: 147  LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXX 206
            LS T ++ DN       K+K +++ + DL++K N+ D    ++ K               
Sbjct: 724  LSKTNEQLDNFNKDKDNKIKELQSKVNDLEKKSNQLDD-ANSRIKELEDELSESEASKDD 782

Query: 207  XXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAAR-- 264
                  D +++   +Q+    M+ +  D +Q   K  +  +   +   + +K L+AA   
Sbjct: 783  ISNKLNDLQKKSNDLQKKSDQMKKDLDDSQQENAKKQKENEDLQNQQRDLDKKLKAAEKR 842

Query: 265  -FEISLEHSKLAQELEQ-XXXXXXXXXXXXXXLAKQS--IEPSCEEKTEIEEKGS--LEI 318
              E+  E+S L + L+                +A+Q+  I+   E     + KG    E+
Sbjct: 843  IQELLGENSDLHETLDNINTSSMQQGDEMNKVIAEQAAKIKALQEAVNNSQPKGEDPNEL 902

Query: 319  AN-MTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRN 377
             + + +L  +I+ L+  N ++ + NKELE        E+  + +  +  +  +S+    N
Sbjct: 903  HDKINDLMAQIKALQQKNNELDKENKELEAAKEASENENNDLKNDLQTKNKALSKAERDN 962

Query: 378  TASKMKSPWSQLSSETLNQDTDK-KINKNEIAKLEMVIQ----SLNKDLVDKEYVISEKD 432
               K+     Q +++ L++  +K K  ++E++ L+ ++      L K+  + E +++ KD
Sbjct: 963  --DKL-----QNANKALDEAKEKIKALEDEVSDLKALVSEKDGDLQKEKRENERLVANKD 1015

Query: 433  TXXXXXXXXXXG-KDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELND 491
                         K+    +++L+ Q       L       E   E+ K  E L QE ND
Sbjct: 1016 QLTKNNEELYDQLKNETTEKIKLDGQVKNAERDLAKANATNE---ELTKSNEHL-QEQND 1071

Query: 492  EIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKV- 550
            E KD  +K+L  KL   E++++    E+      + K K  +     ++Q  +++  K  
Sbjct: 1072 E-KDAKIKELQAKLNELEKKLS----ELPGLQDEIAKQKETN----NELQNNVNDLEKAG 1122

Query: 551  SDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAE 610
             D + +I  L ++ + L     +LE+    L+    D D+      D             
Sbjct: 1123 KDKDNKINELQKKANELENTKKDLEDVTNELENTQKDLDNSNNKNRD------------- 1169

Query: 611  TRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSV-HLEEQID 669
                    LE Q  DL +++  L ++ ++++D+L D S+L  D++    + + +L +QI 
Sbjct: 1170 --------LEKQIKDLKKQIEDLNREKNDLKDQL-DTSKLAGDELSKRDEVLDNLRKQIA 1220

Query: 670  ALSASKKELALVIENLKLDK--EQLYGTIKDLENDKEDIMNKLQNYIQENMDLTD-KLEK 726
             L+A  K+L    EN   D   E+L     +LEN  + +    +   + + +L + K E 
Sbjct: 1221 ELAAKNKDL----ENKANDNNAEELAAKEAELENINKQLEQTKKELAERDEELKNAKNEN 1276

Query: 727  MSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIA 786
            ++ EK ++ L + N  E+ K + Q   D K  E +   +N++ E +  KS++  LE  + 
Sbjct: 1277 LAKEKENQKLNREN--ERLKFEQQ---DLKDLEEE--NKNLDDENAALKSKVNALENDLQ 1329

Query: 787  VMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEH 846
              +     L+   DQL + + +      E + ++ +L  +        +  +++L   + 
Sbjct: 1330 KAKRDADRLKLNNDQLQTNIDDLDNKLKEESAEKIKLDAQA-------KAADRELQSAKA 1382

Query: 847  ENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDL-ES 905
              +E +K N  L  + ++    L +MQ   N + +KAN  D  ++ +   ++QL D  +S
Sbjct: 1383 ATEEEKKANDQLQGQIKDKDNKLKEMQAKLNEMQKKANDADRIQNLANSLKSQLDDANKS 1442

Query: 906  NLKRIT--HEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQ 963
            N ++    +E Q  + + +K+   LE     ++E A  D   LNEK +K ++        
Sbjct: 1443 NNEKDNQLNELQKKLNEAQKKANQLE-PTKQELEDARND---LNEK-QKELDASNNKNRD 1497

Query: 964  LQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDE 1023
            L++    I++L   + +LN       +K   K    +    +  +++ +++   LK++  
Sbjct: 1498 LEK---QIKDLKKQIGDLNN------EKQALKDDLDTSKLADDELSKRDEVLGNLKKQLA 1548

Query: 1024 EIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQI 1083
            + +A N+++  A+V       D   +LA    +L+ +++++++V K L +++   +EL+ 
Sbjct: 1549 DQLAKNKEL-EAKVK-----GDNGDELAAKDAELDALKDQLEQVKKDLAETE---DELKN 1599

Query: 1084 LVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLK 1143
               E   + KE+++     E ++   E  +  +  E  + DA N +             K
Sbjct: 1600 ARNESSAKDKEIQKLARDLE-HLKDAEDDLEKANEEIKNRDAENNELKGQLANKENELQK 1658

Query: 1144 VQEEEEFIQ-ERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSK 1202
             ++E + +Q  +  L + +  LN +L    T  I+L+    EL      N     Q    
Sbjct: 1659 SKQENDRLQLSKDQLSKHNDDLNNQLTAATTDNIKLDAQVKELERRLGTNNAAQEQQAQT 1718

Query: 1203 LEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQ-HLAQREAD-FQKTEHELRVQ 1260
            +EQL +E  +  + + +L   I++ + ++  +   L +Q   A+ + D   K+ ++   Q
Sbjct: 1719 IEQLKSEAADKDNKIKDLHDQINN-LQKKANDADNLQQQLDYAKSQLDEANKSNNDKDNQ 1777

Query: 1261 LSAFESKYEQLLDSVQSSTQEETNKI-VTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQ 1319
            L+  + K+ +        +Q++ N++  T +++   +N L +K++ L     K  D+  Q
Sbjct: 1778 LNELQKKFNE--------SQKKANQLEPTKQELEDSRNDLNEKQKELDESNNKNRDLEKQ 1829

Query: 1320 IEILRSEIED-EKVAFXXXXXXXXXXXXXXXXD-LRTE-NQSYKQMQEQSILNINEENAQ 1376
            I+ L+ +IED +K                   D LR +  +   +++E    N +    +
Sbjct: 1830 IKELKKQIEDLKKQKDDLQEQLDNNVKADDVIDKLRKQIAELLAKVKELEAKNKDNTGDE 1889

Query: 1377 LKKSSXXXXXXXXXXXXRVNDAEAKVLEL---THQLELKDSEIYQKTHEYTITLTQRNDE 1433
            L                   D + K LEL   +  L  KD E+ +   E      +R  +
Sbjct: 1890 LAVKDAEIESLKNQFEQAKKDLDEKELELKQTSDNLSSKDKELQKANRE-----LERLQD 1944

Query: 1434 FENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNV 1493
             +    Q  E  K+++    E +++LA    ++ ++    E +Q  ++ +  K  ++LN 
Sbjct: 1945 VDQELAQANEENKKLDAENGELKTQLANTENELQKSKQDNERLQSSND-QLTKNTDDLNK 2003

Query: 1494 KI----TESVSLNKQVAELNK-------ALEEEVAKTNEMQTALENQEIEIVTLNDEITN 1542
            K+    T+++ LN  + EL +       A+ ++    +++     +++ +I  L+D+I N
Sbjct: 2004 KLTDETTDNIKLNGLIQELQRRLANNDAAIAQQAESIDKLNEQAADKDNKIKDLHDQINN 2063

Query: 1543 LQNMVRASSSKIQKHVSFAS---DTKQGRDEQLDNTMNK 1578
            LQ      +  +Q+ + +A    D     +   DN +N+
Sbjct: 2064 LQKKAN-DADNLQQQLDYAKSQLDEANKSNNDKDNQLNE 2101



 Score =  161 bits (391), Expect = 1e-37
 Identities = 290/1514 (19%), Positives = 636/1514 (42%), Gaps = 122/1514 (8%)

Query: 149  NTIKEKDNALSVLQVKMKIMETTILDLQEKI-NEKDQI----IEAKNKATTXXXXXXXXX 203
            +T+K+KD  ++ L  K+K     I DLQ ++ N K+++     + ++K            
Sbjct: 456  DTLKDKDAKINDLNNKLKDNNKAINDLQNQLDNAKNELENLRKQLESKQNELKDAEKKLN 515

Query: 204  XXXXXXXXEDTKQQMTKMQENFIAMEAEWK-DEKQRLLKDIESKDVRISSLEEANKL-LE 261
                     +T+ +  + Q + I  + E + DE   L K +  +        E NK   E
Sbjct: 516  DAKRKNKDLETENEALQDQVDSINTDKEQQGDELANLRKMLSDQTANFKKNNEDNKKENE 575

Query: 262  AARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANM 321
                +   E+  L  +++Q               A+  ++   ++  + + +        
Sbjct: 576  KELAKKEAENRALQNQIDQLKKLLQGSEEDLKN-AQNELQAKDKDLAKAQRENERLANAQ 634

Query: 322  TELTKKIELLEHLNCQIRQTNKEL---ENKLATMGTES---KAVSSPSKKGSPLISRKSG 375
             +L   +E  ++L+ ++     +L   EN+      E+   KA++   +K S  +++K  
Sbjct: 635  NQLQSNLEEKKNLDDELTDLKSKLAAIENEKQKAERENERLKAMNDQLEKTSDDLNKKLT 694

Query: 376  RNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXX 435
              T  ++K   SQ  +      T K  ++ E++K    + + NKD  +K   +  K    
Sbjct: 695  DETRERIKLD-SQAKAADRELQTAKAASE-ELSKTNEQLDNFNKDKDNKIKELQSKVNDL 752

Query: 436  XXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTN--TEDVNEIAKVQEQLKQELNDEI 493
                      ++ I +L+ E  +       I    N   +  N++ K  +Q+K++L+D  
Sbjct: 753  EKKSNQLDDANSRIKELEDELSESEASKDDISNKLNDLQKKSNDLQKKSDQMKKDLDDSQ 812

Query: 494  KDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVS-- 551
            ++ N K   E  +  + Q   L+ ++ AA K + ++   +      + +T+DN +  S  
Sbjct: 813  QE-NAKKQKEN-EDLQNQQRDLDKKLKAAEKRIQELLGEN----SDLHETLDNINTSSMQ 866

Query: 552  ---DSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIE-SDVYKKMIEMEN 607
               + NK I     ++  L Q+     + KG     L D  +  M +   + +K  E++ 
Sbjct: 867  QGDEMNKVIAEQAAKIKAL-QEAVNNSQPKGEDPNELHDKINDLMAQIKALQQKNNELDK 925

Query: 608  LAETRLKAISLLESQKFDLVQELHILQQKYDEVE---DKLADISQLQSDQVCSEIKSVHL 664
              +    A    E++  DL  +L    +   + E   DKL + ++   D+   +IK+  L
Sbjct: 926  ENKELEAAKEASENENNDLKNDLQTKNKALSKAERDNDKLQNANK-ALDEAKEKIKA--L 982

Query: 665  EEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKL 724
            E+++  L A   E    ++  K + E+L      L  + E++ ++L+N   E + L  ++
Sbjct: 983  EDEVSDLKALVSEKDGDLQKEKRENERLVANKDQLTKNNEELYDQLKNETTEKIKLDGQV 1042

Query: 725  EKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIE---SELSKYKSRICRL 781
            +    +     LAK N   +   ++   +  +  E+D  I+ ++   +EL K  S +  L
Sbjct: 1043 KNAERD-----LAKANATNEELTKSNEHLQEQNDEKDAKIKELQAKLNELEKKLSELPGL 1097

Query: 782  EESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQL 841
            ++ IA  ++    L+   + L    ++K    +E   + +EL N    L D    +E   
Sbjct: 1098 QDEIAKQKETNNELQNNVNDLEKAGKDKDNKINELQKKANELENTKKDLEDVTNELENTQ 1157

Query: 842  LEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLR 901
             ++++ N     KN+ L ++ ++L+  + D+ +  N L ++ + + LA  E +K    L 
Sbjct: 1158 KDLDNSN----NKNRDLEKQIKDLKKQIEDLNREKNDLKDQLDTSKLAGDELSKRDEVLD 1213

Query: 902  DLESNLKRITHEHQTL-----------IVQKKKEIEDLEIEF-NTQIESAIRDKKVLNEK 949
            +L   +  +  +++ L           +  K+ E+E++  +   T+ E A RD+++ N K
Sbjct: 1214 NLRKQIAELAAKNKDLENKANDNNAEELAAKEAELENINKQLEQTKKELAERDEELKNAK 1273

Query: 950  YEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYIN 1009
             E        L  + +  K N EN  +  E+ +  +LE  +K++  +            N
Sbjct: 1274 NE-------NLAKEKENQKLNRENERLKFEQQDLKDLEEENKNLDDENAALKSKVNALEN 1326

Query: 1010 EINKLNALLKQKDEEIIALNQKINNAQVSYM-SMVSDYESKLAQFTTKLENMEEEMQRVS 1068
            ++ K      ++D + + LN       +  + + + +  ++  +   + +  + E+Q   
Sbjct: 1327 DLQK-----AKRDADRLKLNNDQLQTNIDDLDNKLKEESAEKIKLDAQAKAADRELQSAK 1381

Query: 1069 KQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEG---MIISSTIEPMSDDA 1125
                + K+ N++LQ  ++++D+++KE+ + KL  EM     +      ++++++   DDA
Sbjct: 1382 AATEEEKKANDQLQGQIKDKDNKLKEM-QAKLN-EMQKKANDADRIQNLANSLKSQLDDA 1439

Query: 1126 NNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTEL 1185
            N  +             K+ E ++   +    +++      +L E   ++      N +L
Sbjct: 1440 NKSNNEKDNQLNELQK-KLNEAQKKANQLEPTKQELEDARNDLNEKQKELDASNNKNRDL 1498

Query: 1186 TGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQ---H 1242
                   ++QI  LK ++  LN E   L   + +        + +R   +  L KQ    
Sbjct: 1499 -------EKQIKDLKKQIGDLNNEKQALKDDL-DTSKLADDELSKRDEVLGNLKKQLADQ 1550

Query: 1243 LAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDK 1302
            LA+ +    K + +   +L+A +++ + L D ++   Q + +   T +++ + +N+   K
Sbjct: 1551 LAKNKELEAKVKGDNGDELAAKDAELDALKDQLE---QVKKDLAETEDELKNARNESSAK 1607

Query: 1303 EEHLRNLQ---EKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSY 1359
            ++ ++ L    E   D  + +E    EI++ + A                   + EN   
Sbjct: 1608 DKEIQKLARDLEHLKDAEDDLEKANEEIKN-RDAENNELKGQLANKENELQKSKQENDRL 1666

Query: 1360 KQMQEQSILNINEENAQLKKSSXXXXXXXX---------XXXXRVNDAEAKVLE-LTHQL 1409
            +  ++Q   + ++ N QL  ++                        + +A+ +E L  + 
Sbjct: 1667 QLSKDQLSKHNDDLNNQLTAATTDNIKLDAQVKELERRLGTNNAAQEQQAQTIEQLKSEA 1726

Query: 1410 ELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDL---TYEKESELAILRLKM 1466
              KD++I +  H+    L ++ ++ +N++QQL   + ++++      +K+++L  L+ K 
Sbjct: 1727 ADKDNKI-KDLHDQINNLQKKANDADNLQQQLDYAKSQLDEANKSNNDKDNQLNELQKKF 1785

Query: 1467 HEN---ANHYETMQKESEIERVKLIE---ELNVKITESVSLNKQVAELNKALEEEVAKTN 1520
            +E+   AN  E  ++E E  R  L E   EL+    ++  L KQ+ EL K +E+   + +
Sbjct: 1786 NESQKKANQLEPTKQELEDSRNDLNEKQKELDESNNKNRDLEKQIKELKKQIEDLKKQKD 1845

Query: 1521 EMQTALENQ---EIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMN 1577
            ++Q  L+N    +  I  L  +I  L   V+   +K + +       K    E L N   
Sbjct: 1846 DLQEQLDNNVKADDVIDKLRKQIAELLAKVKELEAKNKDNTGDELAVKDAEIESLKNQFE 1905

Query: 1578 KELLDAVPRAELDL 1591
            +   D +   EL+L
Sbjct: 1906 QAKKD-LDEKELEL 1918



 Score =  156 bits (379), Expect = 4e-36
 Identities = 288/1462 (19%), Positives = 612/1462 (41%), Gaps = 126/1462 (8%)

Query: 213  DTKQQMTKMQENFIAMEAEWKDEKQRLL-KDIESKDVRISSLEEANKLLEAARFEISLEH 271
            D + Q+ ++Q+      AE +  K ++  KD+E KD + S +E+  KLL+    +   + 
Sbjct: 238  DLQDQLKRLQDQLDKQTAESQQLKSQIENKDLEGKD-KDSEIEKLKKLLKDKDNKSKNDL 296

Query: 272  SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELT-KKIEL 330
             +    ++                 KQ  + +  +  E E   + ++ N  E + KK +L
Sbjct: 297  DEANANIDDLNKQLDQLRNALKDANKQ--KAAALDDLEKERDANSDLKNKLEDSDKKYKL 354

Query: 331  LEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLS 390
            LE+   Q  Q+ +   +KLA M  E   +   +    P +  +  +N     K   +Q+ 
Sbjct: 355  LEN---QQNQSEEGARSKLAGMEVEFARLQKENNDLKPKLQDEVAKN-----KELQNQI- 405

Query: 391  SETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEY----VISEKDTXXXXXXXXXXGKD 446
             E L    D+   K  +A+ +  I+    ++ D +     V + +             KD
Sbjct: 406  -ENLQDQIDEL--KRSLAEAQKQIKDKEAEIADVKNQLQGVEASQQQQNANAQDTLKDKD 462

Query: 447  TLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVK--DLIEK 504
              I  L  + + + +  + +    +    NE+  +++QL+ + N E+KD   K  D   K
Sbjct: 463  AKINDLNNKLKDNNKAINDLQNQLDNAK-NELENLRKQLESKQN-ELKDAEKKLNDAKRK 520

Query: 505  LKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEEL 564
             K  E +   L D++D+ N +  +         K +     NF K ++ NK+     E  
Sbjct: 521  NKDLETENEALQDQVDSINTDKEQQGDELANLRKMLSDQTANFKKNNEDNKK-----ENE 575

Query: 565  HHLSQKVAELEEEKGNL-QLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQK 623
              L++K AE    +  + QL  +   S   +++   +   + ++LA+ + +   L  +Q 
Sbjct: 576  KELAKKEAENRALQNQIDQLKKLLQGSEEDLKNAQNELQAKDKDLAKAQRENERLANAQN 635

Query: 624  FDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIE 683
              L   L   +   DE+ D  + ++ +++++  +E ++  L+   D L  +  +L   + 
Sbjct: 636  -QLQSNLEEKKNLDDELTDLKSKLAAIENEKQKAERENERLKAMNDQLEKTSDDLNKKLT 694

Query: 684  NLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEE 743
            +   ++ +L    K  + + +      +   + N  L D   K    KI EL +K+N  E
Sbjct: 695  DETRERIKLDSQAKAADRELQTAKAASEELSKTNEQL-DNFNKDKDNKIKELQSKVNDLE 753

Query: 744  QSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLG 803
            +   Q     DA  + ++L  E  ESE SK       +   +  ++ +   L++K+DQ+ 
Sbjct: 754  KKSNQLD---DANSRIKELEDELSESEASKDD-----ISNKLNDLQKKSNDLQKKSDQMK 805

Query: 804  SYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKK----NQILL 859
              L + Q+  ++   + ++L N+   L    +  EK++ E+  EN +L +     N   +
Sbjct: 806  KDLDDSQQENAKKQKENEDLQNQQRDLDKKLKAAEKRIQELLGENSDLHETLDNINTSSM 865

Query: 860  EENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIV 919
            ++   +   +++      AL E  N +     +  +   ++ DL + +K +  ++  L  
Sbjct: 866  QQGDEMNKVIAEQAAKIKALQEAVNNSQPKGEDPNELHDKINDLMAQIKALQQKNNELDK 925

Query: 920  QKKK----------EIEDLEIEFNTQ---IESAIRDKKVL---NEKYEKNIEYVTQLEAQ 963
            + K+          E  DL+ +  T+   +  A RD   L   N+  ++  E +  LE +
Sbjct: 926  ENKELEAAKEASENENNDLKNDLQTKNKALSKAERDNDKLQNANKALDEAKEKIKALEDE 985

Query: 964  LQEYKNNIENLNMNVEELNKMNLELIDKHVQ--KQQTQSPDYTEQYINEINKLNALLKQK 1021
            + + K  +   + ++++  + N  L+    Q  K   +  D  +    E  KL+  +K  
Sbjct: 986  VSDLKALVSEKDGDLQKEKRENERLVANKDQLTKNNEELYDQLKNETTEKIKLDGQVKNA 1045

Query: 1022 DEEII---ALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEE---EMQRVSKQLLDSK 1075
            + ++    A N+++  +         + ++K+ +   KL  +E+   E+  +  ++   K
Sbjct: 1046 ERDLAKANATNEELTKSNEHLQEQNDEKDAKIKELQAKLNELEKKLSELPGLQDEIAKQK 1105

Query: 1076 QHNEELQILV-------REQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNV 1128
            + N ELQ  V       +++D++I EL+  K   E+   K +   +++ +E    D +N 
Sbjct: 1106 ETNNELQNNVNDLEKAGKDKDNKINELQ--KKANELENTKKDLEDVTNELENTQKDLDNS 1163

Query: 1129 DXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQ----------SAKLNTELQECYTKIIQL 1178
            +            LK ++ E+  +E++ L++Q           +K +  L     +I +L
Sbjct: 1164 NNKNRDLEKQIKDLK-KQIEDLNREKNDLKDQLDTSKLAGDELSKRDEVLDNLRKQIAEL 1222

Query: 1179 ETLNTELTGH-DVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAE 1237
               N +L    +  N E++   +++LE +N + +     +AE    + +A ++   +  E
Sbjct: 1223 AAKNKDLENKANDNNAEELAAKEAELENINKQLEQTKKELAERDEELKNAKNENLAKEKE 1282

Query: 1238 LWK-----QHLAQREADFQKTEHE---LRVQLSAFESKYEQLLDSVQSSTQE----ETNK 1285
              K     + L   + D +  E E   L  + +A +SK   L + +Q + ++    + N 
Sbjct: 1283 NQKLNRENERLKFEQQDLKDLEEENKNLDDENAALKSKVNALENDLQKAKRDADRLKLNN 1342

Query: 1286 IVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXX 1345
                  +  L NKL+++      L  +      +++  ++  E+EK A            
Sbjct: 1343 DQLQTNIDDLDNKLKEESAEKIKLDAQAKAADRELQSAKAATEEEKKANDQLQGQIKDKD 1402

Query: 1346 XXXXXDLRTENQSYKQMQE-QSILNI-NEENAQL---KKSSXXXXXXXXXXXXRVNDAEA 1400
                      N+  K+  +   I N+ N   +QL    KS+            ++N+A+ 
Sbjct: 1403 NKLKEMQAKLNEMQKKANDADRIQNLANSLKSQLDDANKSNNEKDNQLNELQKKLNEAQK 1462

Query: 1401 KV--LELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESE 1458
            K   LE T Q EL+D+      +E    L   N++  ++ +Q+ + +K+I DL  EK++ 
Sbjct: 1463 KANQLEPTKQ-ELEDAR--NDLNEKQKELDASNNKNRDLEKQIKDLKKQIGDLNNEKQA- 1518

Query: 1459 LAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQV-AELNKALEEEVA 1517
               L+  +  +    + + K  E+    L ++L  ++ ++  L  +V  +    L  + A
Sbjct: 1519 ---LKDDLDTSKLADDELSKRDEV-LGNLKKQLADQLAKNKELEAKVKGDNGDELAAKDA 1574

Query: 1518 KTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQK------HVSFASDTKQGRDEQ 1571
            + + ++  LE  + ++    DE+ N +N   A   +IQK      H+  A D  +  +E+
Sbjct: 1575 ELDALKDQLEQVKKDLAETEDELKNARNESSAKDKEIQKLARDLEHLKDAEDDLEKANEE 1634

Query: 1572 LDN--TMNKELLDAVPRAELDL 1591
            + N    N EL   +   E +L
Sbjct: 1635 IKNRDAENNELKGQLANKENEL 1656



 Score =  154 bits (374), Expect = 2e-35
 Identities = 238/1141 (20%), Positives = 493/1141 (43%), Gaps = 122/1141 (10%)

Query: 476  NEIAKVQEQLKQEL---NDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSN 532
            N++ K+ +  +Q +    +E++++N K L E  K  ++ +  LN +ID+          N
Sbjct: 110  NQLTKLLQDREQAIARSGEEVENLNNK-LDEAEKKLKDTLNDLNPKIDSLTAE------N 162

Query: 533  HKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGR 592
              LK KQ+Q+     + + +  K + +LT       Q   ELE +K        + D   
Sbjct: 163  ENLK-KQLQEQAPKLADMDNLTKSLKKLTRMQEKAKQ---ELENQKKQ------NADQEN 212

Query: 593  MIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQS 652
                D+     E++N  +         E QK DL  +L  LQ   D+++ + A+  QL+S
Sbjct: 213  KYNQDIDALNKELQNQQQD-------FEKQKNDLQDQLKRLQ---DQLDKQTAESQQLKS 262

Query: 653  DQVCSEIKSVHLEEQIDAL--------SASKKELALV---IENLKLDKEQLYGTIKDLEN 701
                 +++    + +I+ L        + SK +L      I++L    +QL   +KD   
Sbjct: 263  QIENKDLEGKDKDSEIEKLKKLLKDKDNKSKNDLDEANANIDDLNKQLDQLRNALKDANK 322

Query: 702  DKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERD 761
             K   ++ L+     N DL +KLE   ++K  +LL      E  + Q++ G  +K+   +
Sbjct: 323  QKAAALDDLEKERDANSDLKNKLE--DSDKKYKLL------ENQQNQSEEGARSKLAGME 374

Query: 762  LYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQED 821
            +    ++ E +  K    +L++ +A  ++ +  +E   DQ+    +   +A  +   +E 
Sbjct: 375  VEFARLQKENNDLKP---KLQDEVAKNKELQNQIENLQDQIDELKRSLAEAQKQIKDKEA 431

Query: 822  ELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSD-MQQHYNALV 880
            E+ +           V+ QL  +E   ++     Q  L++       L++ ++ +  A+ 
Sbjct: 432  EIAD-----------VKNQLQGVEASQQQQNANAQDTLKDKDAKINDLNNKLKDNNKAIN 480

Query: 881  EKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAI 940
            +  N+ D A++E    + QL   ++ LK    +      +K K++E        Q++S  
Sbjct: 481  DLQNQLDNAKNELENLRKQLESKQNELKD-AEKKLNDAKRKNKDLETENEALQDQVDSIN 539

Query: 941  RDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQS 1000
             DK+   ++     + ++   A  +  KNN +N   N +EL K   E  ++ +Q Q  Q 
Sbjct: 540  TDKEQQGDELANLRKMLSDQTANFK--KNNEDNKKENEKELAKKEAE--NRALQNQIDQL 595

Query: 1001 PDYTEQYINEINKLNALLKQKDEEIIAL---NQKINNAQVSYMSMVSD---YESKLAQFT 1054
                +    ++      L+ KD+++      N+++ NAQ    S + +    + +L    
Sbjct: 596  KKLLQGSEEDLKNAQNELQAKDKDLAKAQRENERLANAQNQLQSNLEEKKNLDDELTDLK 655

Query: 1055 TKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKEL-KETKLTFEMNIPKTEGMI 1113
            +KL  +E E Q+  ++    K  N++L+   +  DD  K+L  ET+   +++        
Sbjct: 656  SKLAAIENEKQKAERENERLKAMNDQLE---KTSDDLNKKLTDETRERIKLDSQAKAADR 712

Query: 1114 ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYT 1173
               T +  S++ +  +             K++E +  + +      Q    N+ ++E   
Sbjct: 713  ELQTAKAASEELSKTNEQLDNFNKDKDN-KIKELQSKVNDLEKKSNQLDDANSRIKE--- 768

Query: 1174 KIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGF 1233
              ++ E   +E +  D+ N  ++N L+ K   L  ++D +   + +  S   +A  Q+  
Sbjct: 769  --LEDELSESEASKDDISN--KLNDLQKKSNDLQKKSDQMKKDLDD--SQQENAKKQK-- 820

Query: 1234 EIAELWKQHLAQREADFQKTEHELRVQ-LSAFESKYEQLLDSVQSSTQ---EETNKIVTM 1289
            E  +L  Q   QR+ D +    E R+Q L    S   + LD++ +S+    +E NK++  
Sbjct: 821  ENEDLQNQ---QRDLDKKLKAAEKRIQELLGENSDLHETLDNINTSSMQQGDEMNKVIAE 877

Query: 1290 E--QVTSLQ---NKLQDKEEHLRNLQEKYADVINQIEILR---SEIEDEKVAFXXXXXXX 1341
            +  ++ +LQ   N  Q K E    L +K  D++ QI+ L+   +E++ E           
Sbjct: 878  QAAKIKALQEAVNNSQPKGEDPNELHDKINDLMAQIKALQQKNNELDKENKELEAAKEAS 937

Query: 1342 XXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAK 1401
                     DL+T+N++  + +       N++     K+              V+D +A 
Sbjct: 938  ENENNDLKNDLQTKNKALSKAERD-----NDKLQNANKALDEAKEKIKALEDEVSDLKAL 992

Query: 1402 VLELTHQLELKDSEIYQKTHEYTITLTQRNDE-FENVRQQLVEYEKRIEDLTYEKESELA 1460
            V E    L+ K+    ++       LT+ N+E ++ ++ +  E + +++      E +LA
Sbjct: 993  VSEKDGDLQ-KEKRENERLVANKDQLTKNNEELYDQLKNETTE-KIKLDGQVKNAERDLA 1050

Query: 1461 ILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTN 1520
                   E     E +Q++++ E+   I+EL  K+ E   L K+++EL   L++E+AK  
Sbjct: 1051 KANATNEELTKSNEHLQEQND-EKDAKIKELQAKLNE---LEKKLSEL-PGLQDEIAKQK 1105

Query: 1521 EMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQ---KHVSFASDTKQGRDEQLDNTMN 1577
            E    L+N   ++     +  N  N ++  +++++   K +   ++  +   + LDN+ N
Sbjct: 1106 ETNNELQNNVNDLEKAGKDKDNKINELQKKANELENTKKDLEDVTNELENTQKDLDNSNN 1165

Query: 1578 K 1578
            K
Sbjct: 1166 K 1166



 Score =  149 bits (360), Expect = 8e-34
 Identities = 261/1221 (21%), Positives = 518/1221 (42%), Gaps = 110/1221 (9%)

Query: 446  DTLIAQLQ-LEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEK 504
            D+L A+ + L+ Q   + P L  +   T+ + ++ ++QE+ KQEL ++      K   ++
Sbjct: 156  DSLTAENENLKKQLQEQAPKLADMDNLTKSLKKLTRMQEKAKQELENQ-----KKQNADQ 210

Query: 505  LKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTE-- 562
                 + I  LN E+    ++  K K++ + +LK++Q  +D  +  S   K  +   +  
Sbjct: 211  ENKYNQDIDALNKELQNQQQDFEKQKNDLQDQLKRLQDQLDKQTAESQQLKSQIENKDLE 270

Query: 563  --ELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAE--TRLKAISL 618
              +     +K+ +L ++K N   +  D D       D+ K++ ++ N  +   + KA +L
Sbjct: 271  GKDKDSEIEKLKKLLKDKDNKSKN--DLDEANANIDDLNKQLDQLRNALKDANKQKAAAL 328

Query: 619  --LESQK---FDLVQELHILQQKYDEVEDKLADISQ-LQSDQVCSEIKSVHLEEQIDALS 672
              LE ++    DL  +L    +KY  +E++     +  +S     E++   L+++ + L 
Sbjct: 329  DDLEKERDANSDLKNKLEDSDKKYKLLENQQNQSEEGARSKLAGMEVEFARLQKENNDLK 388

Query: 673  -------ASKKELALVIENLKLDKEQLYGT-------IKDLENDKEDIMNKLQ----NYI 714
                   A  KEL   IENL+   ++L  +       IKD E +  D+ N+LQ    +  
Sbjct: 389  PKLQDEVAKNKELQNQIENLQDQIDELKRSLAEAQKQIKDKEAEIADVKNQLQGVEASQQ 448

Query: 715  QENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKY 774
            Q+N +  D L+   A KI++L  K+    ++    Q  +D    E +   + +ES+ ++ 
Sbjct: 449  QQNANAQDTLKDKDA-KINDLNNKLKDNNKAINDLQNQLDNAKNELENLRKQLESKQNEL 507

Query: 775  KSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYT----IQEDELVNRLAVL 830
            K    +L ++    +D     E   DQ+ S   +K++   E      +  D+  N     
Sbjct: 508  KDAEKKLNDAKRKNKDLETENEALQDQVDSINTDKEQQGDELANLRKMLSDQTANFKKNN 567

Query: 831  MDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAE 890
             D+ +  EK+L + E EN+ LQ  NQI  +  + LQ S  D++   N L  K      A+
Sbjct: 568  EDNKKENEKELAKKEAENRALQ--NQI-DQLKKLLQGSEEDLKNAQNELQAKDKDLAKAQ 624

Query: 891  SESTKYQTQLRDLESNL---KRITHEHQTL-----IVQKKKEIEDLEIE----FNTQIES 938
             E+ +       L+SNL   K +  E   L      ++ +K+  + E E     N Q+E 
Sbjct: 625  RENERLANAQNQLQSNLEEKKNLDDELTDLKSKLAAIENEKQKAERENERLKAMNDQLEK 684

Query: 939  AIRD-KKVLNEKYEKNIEYVTQLEA---QLQEYKNNIENLNMNVEELNKMNLELIDKHVQ 994
               D  K L ++  + I+  +Q +A   +LQ  K   E L+   E+L+  N +  D  ++
Sbjct: 685  TSDDLNKKLTDETRERIKLDSQAKAADRELQTAKAASEELSKTNEQLDNFNKDK-DNKIK 743

Query: 995  KQQTQSPDYTEQYINEINKLNALLKQKDEEII---ALNQKINNAQVSYMSMVSDYESKLA 1051
            + Q++  D  E+  N+++  N+ +K+ ++E+    A    I+N         +D + K  
Sbjct: 744  ELQSKVND-LEKKSNQLDDANSRIKELEDELSESEASKDDISNKLNDLQKKSNDLQKKSD 802

Query: 1052 QFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEG 1111
            Q    L++ ++E  +  K+  D +    +L   ++  + +I+EL    L    ++ +T  
Sbjct: 803  QMKKDLDDSQQENAKKQKENEDLQNQQRDLDKKLKAAEKRIQEL----LGENSDLHETLD 858

Query: 1112 MIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQEC 1171
             I +S+++   D+ N V               V   +   ++ + L ++   L  +++  
Sbjct: 859  NINTSSMQ-QGDEMNKV-IAEQAAKIKALQEAVNNSQPKGEDPNELHDKINDLMAQIKAL 916

Query: 1172 YTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLN-----TENDN-LLSTVAELRSSIS 1225
              K  +L+  N EL      ++ + N LK+ L+  N      E DN  L    +      
Sbjct: 917  QQKNNELDKENKELEAAKEASENENNDLKNDLQTKNKALSKAERDNDKLQNANKALDEAK 976

Query: 1226 SAVDQRGFEIAELWKQHLAQREADFQKTEHE---LRVQLSAFESKYEQLLDSVQSSTQEE 1282
              +     E+++L K  +++++ D QK + E   L           E+L D +++ T E+
Sbjct: 977  EKIKALEDEVSDL-KALVSEKDGDLQKEKRENERLVANKDQLTKNNEELYDQLKNETTEK 1035

Query: 1283 -------TNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFX 1335
                    N    + +  +   +L    EHL+   ++    I +++   +E+E +K++  
Sbjct: 1036 IKLDGQVKNAERDLAKANATNEELTKSNEHLQEQNDEKDAKIKELQAKLNELE-KKLSEL 1094

Query: 1336 XXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRV 1395
                           +L+      ++  +     INE    L+K +              
Sbjct: 1095 PGLQDEIAKQKETNNELQNNVNDLEKAGKDKDNKINE----LQKKANELENTKKDLEDVT 1150

Query: 1396 NDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQL-------VEYEKRI 1448
            N+ E    +L +    K+ ++ ++  +    +   N E  +++ QL        E  KR 
Sbjct: 1151 NELENTQKDLDNS-NNKNRDLEKQIKDLKKQIEDLNREKNDLKDQLDTSKLAGDELSKRD 1209

Query: 1449 E--DLTYEKESELAILRLKMHENANH---YETMQKESEIERV-KLIEELNVKITESVSLN 1502
            E  D   ++ +ELA     +   AN     E   KE+E+E + K +E+   ++ E     
Sbjct: 1210 EVLDNLRKQIAELAAKNKDLENKANDNNAEELAAKEAELENINKQLEQTKKELAERDEEL 1269

Query: 1503 KQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFAS 1562
            K     N A E+E  K N     L+ ++ ++  L +E  NL +   A  SK+    +   
Sbjct: 1270 KNAKNENLAKEKENQKLNRENERLKFEQQDLKDLEEENKNLDDENAALKSKVNALENDLQ 1329

Query: 1563 DTKQGRDE-QLDNTMNKELLD 1582
              K+  D  +L+N   +  +D
Sbjct: 1330 KAKRDADRLKLNNDQLQTNID 1350



 Score =  116 bits (278), Expect = 7e-24
 Identities = 173/837 (20%), Positives = 358/837 (42%), Gaps = 67/837 (8%)

Query: 765  ENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELV 824
            E +    ++  ++I   +E+ A  E       +K +QL   LQ++++A +    + + L 
Sbjct: 75   EYLTERQNQTDNQIKESKENQAKYEATLRQAVKKHNQLTKLLQDREQAIARSGEEVENLN 134

Query: 825  NRL----AVLMDHDRVVEKQLLEIEHENKELQKKNQ---ILLEENQNLQISLSDM-QQHY 876
            N+L      L D    +  ++  +  EN+ L+K+ Q     L +  NL  SL  + +   
Sbjct: 135  NKLDEAEKKLKDTLNDLNPKIDSLTAENENLKKQLQEQAPKLADMDNLTKSLKKLTRMQE 194

Query: 877  NALVEKANRTDLAESESTKYQTQL----RDLESNLKRITHEHQTLIVQKKKEIEDLEIEF 932
             A  E  N+      +  KY   +    ++L++  +    +   L  Q K+  + L+ + 
Sbjct: 195  KAKQELENQKKQNADQENKYNQDIDALNKELQNQQQDFEKQKNDLQDQLKRLQDQLDKQT 254

Query: 933  --NTQIESAIRDKKVLNEKYEKNIEYVTQ-LEAQLQEYKNNIENLNMNVEELNKMNLELI 989
              + Q++S I +K +  +  +  IE + + L+ +  + KN+++  N N+++LNK   +L 
Sbjct: 255  AESQQLKSQIENKDLEGKDKDSEIEKLKKLLKDKDNKSKNDLDEANANIDDLNKQLDQLR 314

Query: 990  D--KHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYE 1047
            +  K   KQ+  + D  E+  +  + L   L+  D++   L  + N ++           
Sbjct: 315  NALKDANKQKAAALDDLEKERDANSDLKNKLEDSDKKYKLLENQQNQSE-------EGAR 367

Query: 1048 SKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIP 1107
            SKLA    +   +++E   +  +L D    N+ELQ  +    DQI ELK +    +  I 
Sbjct: 368  SKLAGMEVEFARLQKENNDLKPKLQDEVAKNKELQNQIENLQDQIDELKRSLAEAQKQIK 427

Query: 1108 KTEGMIISSTIEPMSDDAN-NVDXXXXXXXXXXXXLKVQEEEEFIQERS-VLQEQSAKLN 1165
              E  I     +    +A+                 K+ +    +++ +  + +   +L+
Sbjct: 428  DKEAEIADVKNQLQGVEASQQQQNANAQDTLKDKDAKINDLNNKLKDNNKAINDLQNQLD 487

Query: 1166 TELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSIS 1225
                E      QLE+   EL       ++++N  K K + L TEN+ L   V     SI+
Sbjct: 488  NAKNELENLRKQLESKQNELKD----AEKKLNDAKRKNKDLETENEALQDQV----DSIN 539

Query: 1226 SAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNK 1285
            +  +Q+G E+A L K  L+ + A+F+K            ++K E   +  + + +E  N+
Sbjct: 540  TDKEQQGDELANLRKM-LSDQTANFKKNNE---------DNKKE---NEKELAKKEAENR 586

Query: 1286 IVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXX 1345
             +   Q+  L+  LQ  EE L+N Q +        ++ +++ E+E++A            
Sbjct: 587  AL-QNQIDQLKKLLQGSEEDLKNAQNELQ--AKDKDLAKAQRENERLANAQNQLQSNLEE 643

Query: 1346 XXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLEL 1405
                 D  T+ +S     E        EN +LK  +            ++ D   + ++L
Sbjct: 644  KKNLDDELTDLKSKLAAIENEKQKAERENERLKAMNDQLEKTSDDLNKKLTDETRERIKL 703

Query: 1406 THQLELKDSEIYQKTHEYTITLTQRNDEFENVRQ----QLVEYEKRIEDLTYEKESELAI 1461
              Q +  D E+ Q     +  L++ N++ +N  +    ++ E + ++ DL  +K ++L  
Sbjct: 704  DSQAKAADREL-QTAKAASEELSKTNEQLDNFNKDKDNKIKELQSKVNDLE-KKSNQLDD 761

Query: 1462 LRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNE 1521
               ++ E     E    ESE  +  +  +LN    +S  L K+  ++ K L++     ++
Sbjct: 762  ANSRIKE----LEDELSESEASKDDISNKLNDLQKKSNDLQKKSDQMKKDLDD-----SQ 812

Query: 1522 MQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNK 1578
             + A + +E E   L ++  +L   ++A+  +IQ+ +   SD  +  D    ++M +
Sbjct: 813  QENAKKQKENE--DLQNQQRDLDKKLKAAEKRIQELLGENSDLHETLDNINTSSMQQ 867



 Score =  103 bits (248), Expect = 3e-20
 Identities = 143/736 (19%), Positives = 312/736 (42%), Gaps = 67/736 (9%)

Query: 883  ANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRD 942
            +N TD ++SE ++ Q  L +L + L ++ H+   +I QK  +    +  F    +S    
Sbjct: 8    SNATDGSKSEKSQNQ-YLWELTNGLVKV-HDDIDIIDQKIGKSSAQDRSFQMNPKSIFPR 65

Query: 943  KKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPD 1002
             +++ +  +   EY+T+ + Q     N I+    N  +      + + KH   Q T+   
Sbjct: 66   LEIVCKNLD---EYLTERQNQTD---NQIKESKENQAKYEATLRQAVKKH--NQLTKLLQ 117

Query: 1003 YTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEE 1062
              EQ I           +  EE+  LN K++ A+      ++D   K+   T + EN+++
Sbjct: 118  DREQAI----------ARSGEEVENLNNKLDEAEKKLKDTLNDLNPKIDSLTAENENLKK 167

Query: 1063 EMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMS 1122
            ++Q  + +L D     + L+ L R Q+   +EL+  K   + N  +      +  I+ ++
Sbjct: 168  QLQEQAPKLADMDNLTKSLKKLTRMQEKAKQELENQK---KQNADQENK--YNQDIDALN 222

Query: 1123 DDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLN 1182
             +  N                 + +++  ++ +  Q+  +++  +  E   K  ++E L 
Sbjct: 223  KELQNQQQDFEKQKNDLQDQLKRLQDQLDKQTAESQQLKSQIENKDLEGKDKDSEIEKLK 282

Query: 1183 TELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVD--QRGFEIAELWK 1240
              L   D  ++  +++  + ++ LN + D L + + +     ++A+D  ++  +     K
Sbjct: 283  KLLKDKDNKSKNDLDEANANIDDLNKQLDQLRNALKDANKQKAAALDDLEKERDANSDLK 342

Query: 1241 QHLAQREADFQ-------KTEHELRVQLSAFESKYEQL----------LDSVQSSTQEET 1283
              L   +  ++       ++E   R +L+  E ++ +L          L    +  +E  
Sbjct: 343  NKLEDSDKKYKLLENQQNQSEEGARSKLAGMEVEFARLQKENNDLKPKLQDEVAKNKELQ 402

Query: 1284 NKIVTM-EQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXX 1342
            N+I  + +Q+  L+  L + ++ +++ + + ADV NQ++ + +  + +            
Sbjct: 403  NQIENLQDQIDELKRSLAEAQKQIKDKEAEIADVKNQLQGVEASQQQQNANAQDTLKDKD 462

Query: 1343 XXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKV 1402
                     L+  N++   +Q Q + N   E   L+K              ++NDA+ K 
Sbjct: 463  AKINDLNNKLKDNNKAINDLQNQ-LDNAKNELENLRKQLESKQNELKDAEKKLNDAKRK- 520

Query: 1403 LELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQ----QLVEYEKRIEDLTYEKESE 1458
                  LE ++  +  +         Q+ DE  N+R+    Q   ++K  ED   E E E
Sbjct: 521  ---NKDLETENEALQDQVDSINTDKEQQGDELANLRKMLSDQTANFKKNNEDNKKENEKE 577

Query: 1459 LAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAK 1518
            LA    +     N  + ++K  +       E+L     E  + +K +A+  +  E     
Sbjct: 578  LAKKEAENRALQNQIDQLKKLLQGSE----EDLKNAQNELQAKDKDLAKAQRENERLANA 633

Query: 1519 TNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNT--- 1575
             N++Q+ LE ++     L+DE+T+L++ + A  ++ QK     ++  +  ++QL+ T   
Sbjct: 634  QNQLQSNLEEKK----NLDDELTDLKSKLAAIENEKQK-AERENERLKAMNDQLEKTSDD 688

Query: 1576 MNKELLDAV-PRAELD 1590
            +NK+L D    R +LD
Sbjct: 689  LNKKLTDETRERIKLD 704



 Score = 72.1 bits (169), Expect = 1e-10
 Identities = 115/575 (20%), Positives = 232/575 (40%), Gaps = 41/575 (7%)

Query: 149  NTIKEKDNALSVLQVKMKIMETTILDLQEK---INEKDQIIEAKNKATTXXXXXXXXXXX 205
            N + E     +  Q K   +E T  +L++    +NEK + ++  N               
Sbjct: 1776 NQLNELQKKFNESQKKANQLEPTKQELEDSRNDLNEKQKELDESNNKNRDLEKQIKELKK 1835

Query: 206  XXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARF 265
                  ED K+Q   +QE  +    +  D   +L K I     ++  LE  NK  +    
Sbjct: 1836 QI----EDLKKQKDDLQEQ-LDNNVKADDVIDKLRKQIAELLAKVKELEAKNK--DNTGD 1888

Query: 266  EISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELT 325
            E++++ +++     Q              L + S   S ++K E++ K + E+  + ++ 
Sbjct: 1889 ELAVKDAEIESLKNQFEQAKKDLDEKELELKQTSDNLSSKDK-ELQ-KANRELERLQDVD 1946

Query: 326  KKIELLEHLNCQIRQTNKELENKLATMGTE---SKAVSSPSKKGSPLISRKSGRNTASKM 382
            +++      N ++   N EL+ +LA    E   SK  +   +  +  +++ +        
Sbjct: 1947 QELAQANEENKKLDAENGELKTQLANTENELQKSKQDNERLQSSNDQLTKNTDDLNKKLT 2006

Query: 383  KSPWSQLSSETLNQDTDKKINKNE--IAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXX 440
                  +    L Q+  +++  N+  IA+    I  LN+   DK+  I +          
Sbjct: 2007 DETTDNIKLNGLIQELQRRLANNDAAIAQQAESIDKLNEQAADKDNKIKDLHDQINNLQK 2066

Query: 441  XXXGKDTLIAQL-----QLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQL---KQELNDE 492
                 D L  QL     QL+            +    +  NE  K   QL   KQEL D 
Sbjct: 2067 KANDADNLQQQLDYAKSQLDEANKSNNDKDNQLNELQKKFNESQKKANQLEPTKQELEDS 2126

Query: 493  IKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSD 552
              D+N     EK K  +E   + N +++   K + K   N   + + +Q  +D+     D
Sbjct: 2127 RNDLN-----EKQKELDESNNK-NRDLEKQIKELKKQIGNLDSEKQALQDKLDDIKLADD 2180

Query: 553  SNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMI----ESDVYKKMIEM--E 606
            +   I +  E L +L +++AEL  +  +L+    D ++  +     E +   K +E   +
Sbjct: 2181 A---ISKRDEVLDNLRKQIAELAAKNKDLENKANDNNAEELAAKEAELENINKQLEQTKK 2237

Query: 607  NLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEE 666
             LAE R + +   +++     +E   L ++ + ++ +  D+  L+ +    + ++  L+ 
Sbjct: 2238 ELAE-RDEELKNAKNENLAKEKENQKLNRENERLKFEQQDLKDLEEENKNLDDENAALKS 2296

Query: 667  QIDALSASKKELALVIENLKLDKEQLYGTIKDLEN 701
            +++AL    ++     + LKL+ +QL   I DL+N
Sbjct: 2297 KVNALENDLQKAKRDADRLKLNNDQLQTNIDDLDN 2331


>UniRef50_UPI00006CE95F Cluster: Viral A-type inclusion protein repeat
            containing protein; n=1; Tetrahymena thermophila
            SB210|Rep: Viral A-type inclusion protein repeat
            containing protein - Tetrahymena thermophila SB210
          Length = 1668

 Score =  181 bits (441), Expect = 1e-43
 Identities = 298/1476 (20%), Positives = 633/1476 (42%), Gaps = 131/1476 (8%)

Query: 147  LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINE--KDQIIEAKNKATTXXXXXXXXXX 204
            L   +KEK+NA   LQ ++K+ E  +  L++ +++  + QI E +N              
Sbjct: 271  LDQALKEKENAQKELQDQLKMKEDEVEQLKKDLDQQKQQQIQEVQN-------------- 316

Query: 205  XXXXXXXEDTKQQMTKMQENFIAMEAEWKDE---KQRLLKDIESKDVRISSLEEANKLLE 261
                   +D  +++  +QE    +E++  +E   KQ+L++++E K  ++S L++   L++
Sbjct: 317  -----LKQDQSKEVLTLQEKIGVLESKVSEETASKQKLIEEVEQKGKQVSQLQDQINLIK 371

Query: 262  AARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPS---CEEKTEIEE--KGSL 316
                + S +  KL ++  Q                ++    S    EE ++ +E  K + 
Sbjct: 372  E---QSSSDQDKLMEQKNQEIKELKDQIENIQQKIEEQTNSSNSLSEELSQAKEELKKAQ 428

Query: 317  EIANMTELTKKI--ELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKS 374
            E   ++E  K+   E +  LN QI + + +++     +  +   ++   +K    I    
Sbjct: 429  EQFQLSEKEKQTLKEQISQLNLQIEEKSTQIQEVQNELSQKLNEIAQKDEK----IKHLE 484

Query: 375  GRNTASKMKSPWSQLSSETLNQDTDKKINKN-EIAKLEMVIQSLNKDLVDKEYVISEKDT 433
              NT+S  +S   +L  E  N+  ++ I K+ +I  L + IQ+  K+  +++  + EK+ 
Sbjct: 485  SENTSSLSQS--EELGKE-FNEIREQMIQKDQQIDNLNVNIQAKEKE-YNEQLQLKEKEY 540

Query: 434  XXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEI 493
                       K+      QL  +  +   + I +  + + + +     E+LKQ +  E 
Sbjct: 541  SEKLDKINEEIKNLNEVISQLNEENKI---AKIQIEESNKSIQKYENDIEELKQNIETEK 597

Query: 494  K--DVNVKDLIEKLKSAEEQITQLN----DEIDAANKNMIKVKSNHKLKLKQMQKTI--- 544
            K  +  + +L E  K   E I   N     E++  N N ++  +N + +L ++Q+ I   
Sbjct: 598  KQSENQITELQEIHKKQIEDINSQNIAKIQELENKNVNQVQEINNSQDQLHKLQEEIKSL 657

Query: 545  -DNFSKVSDSNKEI-VRLTEELHHLSQKVAELEEEKGNL----QLHLVDYDSGRMIESDV 598
             +  +K++D NK I ++L E    + +++ +++E   NL    Q    +    +    ++
Sbjct: 658  NEQIAKLNDENKIINIQLEESTKSIQKQIQDIKELSENLETQKQSAQEEIQKQKSELEEL 717

Query: 599  YKKMIE-MENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCS 657
            +KK IE + N   T+++ +    S K + +   H  ++  +E+ED    +++    +   
Sbjct: 718  HKKQIESINNQNNTKIQELENSHSNKVEELNNSH--KKLIEELEDSHKKVTEDIQHKNAH 775

Query: 658  EIKSVH--LEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLEN---DKEDIMNKLQN 712
            E+K +   L E      + +++++L     +  + +    IKDLEN   +K D M  L++
Sbjct: 776  ELKKIQEILSETQQREKSLQEQISLHSMGAEQQEVERQKIIKDLENQIKEKADQMRNLED 835

Query: 713  YIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELS 772
             I+   D   K ++   EK +  +  +  +E  + +T   + A ++       NI  +  
Sbjct: 836  QIELLNDQNSK-QQADNEKQNLQIQDLTQKEAQQQETINKLKADLENAKQIELNINEQNE 894

Query: 773  KYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMD 832
             +K    +LEES   +   +  LE  +  L    + + +       Q ++L+N    L  
Sbjct: 895  AFKK---QLEESKQNLSQLQKELEESSKNLSDSKENQNEEILSLKKQIEDLLNLKTELET 951

Query: 833  HDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESE 892
             +  +     EI+    E Q+K     EE Q    SL D  ++ +  +++   T+L + +
Sbjct: 952  SNNKINTLNQEIDALKNEKQQKE----EEYQKQINSLKDQSKNNDNNIQQ--ETELLKQQ 1005

Query: 893  STKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIE--SAIRDKKVLNEKY 950
            + K + QL++L+ +  +I  E    I  K+KE++D +     Q+   + ++D+    ++ 
Sbjct: 1006 NKKLEEQLKELKDSELQILEE----IQNKEKEVDDFKQINEQQLNEINQLKDELASQKQK 1061

Query: 951  EKNIEYVTQLEAQLQEYKNNIENLNMNVE-ELNKMNLELIDKHVQKQQTQSPDYTEQYIN 1009
            +   E  TQ E+QL E K   E + ++++ +L ++N   + K  +  Q +  D+ ++  +
Sbjct: 1062 DNQQEQETQGESQLDELKVKYEQVELDLKSKLEEIN--QLQKQNENLQREKLDFEKEIAD 1119

Query: 1010 EINKLNALLKQKDEEIIAL-NQKINNAQVSYMSM-----VSDYESKLAQFTTKLENMEEE 1063
              ++LN+        II L N  +N++     S      V++ E K  +     ++ +EE
Sbjct: 1120 MKSQLNSTAFSSSNNIINLENSAMNDSTTPRNSSLVSTPVNNEEKKDNEDKKDEKDKKEE 1179

Query: 1064 MQRVSKQLLDSKQHNEELQI-LVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMS 1122
              + SK+    KQ   ++ +  +++ D+Q+KELK+ +   E    + +  +   + +P+ 
Sbjct: 1180 KDKKSKEAKSDKQQTVKMTLEELKKWDEQVKELKKKRKELEKENKQLKQELEEKSKQPVQ 1239

Query: 1123 --DDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLET 1180
              D    ++            LK++ EE+   ++S  Q+    LN E  E   +I+Q   
Sbjct: 1240 NIDSLKQIESQKRQLEQQYMNLKIELEEKNKLQQS--QQIKKNLNLESLEERCRILQ--- 1294

Query: 1181 LNTELTGHDVVNQEQINQLKSKLEQLNTE-NDNLLSTVAELRSSISSAVDQRGFEIAELW 1239
                L   + VN ++ ++ +   ++  T   ++  +   EL+    SA ++   E+  L 
Sbjct: 1295 ---GLLDENSVNLQKADREREYWKEKYTGLQEDFNAKEEELKIQRESAREKFNLEMT-LQ 1350

Query: 1240 KQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKI-VTMEQVTSLQNK 1298
             Q       + Q  E+E  +Q     +   + L    +  +E  +K+   +E     Q K
Sbjct: 1351 SQIQQNSSLNKQIQEYERNLQAYKQLNADNENLKKECAKLRELVDKLQEELENKERNQEK 1410

Query: 1299 LQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQS 1358
            L  K   L  L ++Y   IN +E     ++++K +                 +++  NQ 
Sbjct: 1411 LSHKLNELNELNDEYQKKINYLEKQSERLQNQK-SELEQNLQSITTQLEDSQNIQKINQK 1469

Query: 1359 YKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQ 1418
              Q +   I  + +   Q  K               + +A  K    T  +   + E  +
Sbjct: 1470 KYQNEVLEIKQVRDGLVQQVKELKTKNESLENDVRSLREANKKQFHSTINV---NPETAK 1526

Query: 1419 KTHEYTITLTQRNDEFE-NVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQ 1477
            K      +L+ RN E E N  Q L+         +++   ++ IL+++  +  +  E M 
Sbjct: 1527 KDKIILESLSIRNQELEVNFNQNLI---------SFKANKQIVILKVQSKQQKDKIEFMD 1577

Query: 1478 KE-SEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTL 1536
            K+  EI +V     L  KI    +L+K++   N    E++    E +   E +  +++  
Sbjct: 1578 KQIKEIHKV-----LESKIAIIQNLSKELFHKNPT-SEDIKDIYEQKELQEVKNYKLMNY 1631

Query: 1537 NDEITNLQNMVRASSSKIQKHV-SFASDTKQGRDEQ 1571
              EI +L   +   + +++K+V     + K+  D Q
Sbjct: 1632 K-EIQDLIEKMSIENIRMRKNVLILGQELKEAMDSQ 1666



 Score =  178 bits (434), Expect = 9e-43
 Identities = 309/1496 (20%), Positives = 647/1496 (43%), Gaps = 150/1496 (10%)

Query: 152  KEKDNAL---SVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXX 208
            KE+D+ L   S +  + + +E  +  L+E+  ++ Q   ++++A                
Sbjct: 47   KEQDDILIQLSTIDSEKQELEKELQQLKEQ-QQQSQGNSSESEALQQELNKQKDKHSELE 105

Query: 209  XXXEDTKQQMTKMQENFIAMEA-EWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEI 267
                + K    K+Q     +++ +++++ Q+  K I   + +I   +E NK L     E+
Sbjct: 106  LEINNLKDTNQKLQAKIEEIQSHKYEEQIQQNEKKIAELNSQIDKQDEENKSLNGKLQEL 165

Query: 268  SLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGS-LEIAN--MTEL 324
              E     Q++ Q              L +++     E K +++ K   +  AN  + +L
Sbjct: 166  ESEIKSTHQQIAQKEQDLQKQKEDSDSLLEKTKLELEENKKQLDIKNQEINDANQKVNDL 225

Query: 325  TKKIELLEHLNCQIRQTNKELENKLAT-----MGTESKAVSSPSKKGSPLISRKSGRNTA 379
              K++     N + +   K+LE+K++       G ++K +S   KK    +  K      
Sbjct: 226  ENKLKDSGSTNEEFQLKQKDLEDKISQADETKQGLQNK-LSELEKKLDQALKEKENAQKE 284

Query: 380  SKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXX 439
             + +    +   E L +D D++  + +I +++ + Q  +K+++  +  I   ++      
Sbjct: 285  LQDQLKMKEDEVEQLKKDLDQQ-KQQQIQEVQNLKQDQSKEVLTLQEKIGVLESKVSEET 343

Query: 440  XXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVK 499
                 K  LI +++ + +Q  +    I++    +  ++  K+ EQ  QE+  E+KD  ++
Sbjct: 344  AS---KQKLIEEVEQKGKQVSQLQDQINL-IKEQSSSDQDKLMEQKNQEIK-ELKD-QIE 397

Query: 500  DLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVS-DSNKEIV 558
            ++ +K++        L++E+  A + + K +   +L  K+ Q   +  S+++    ++  
Sbjct: 398  NIQQKIEEQTNSSNSLSEELSQAKEELKKAQEQFQLSEKEKQTLKEQISQLNLQIEEKST 457

Query: 559  RLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISL 618
            ++ E  + LSQK+ E+ ++   ++ HL   ++  + +S+   K  E   + E  +     
Sbjct: 458  QIQEVQNELSQKLNEIAQKDEKIK-HLESENTSSLSQSEELGK--EFNEIREQMI----- 509

Query: 619  LESQKFDLVQELHI-LQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKE 677
               QK   +  L++ +Q K  E  ++L             ++K     E++D ++   K 
Sbjct: 510  ---QKDQQIDNLNVNIQAKEKEYNEQL-------------QLKEKEYSEKLDKINEEIKN 553

Query: 678  LALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLA 737
            L  VI   +L++E     I+  E++K   + K +N I+E     +  +K S  +I+EL  
Sbjct: 554  LNEVIS--QLNEENKIAKIQIEESNKS--IQKYENDIEELKQNIETEKKQSENQITEL-Q 608

Query: 738  KINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLER 797
            +I+ ++   I +Q  I AKIQE +    N   E++  + ++ +L+E I  + ++   L  
Sbjct: 609  EIHKKQIEDINSQ-NI-AKIQELENKNVNQVQEINNSQDQLHKLQEEIKSLNEQIAKLND 666

Query: 798  KADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDH-DRVVEKQLLEIEHENKELQKKNQ 856
            +   +   L+E  K+  +      EL   L          ++KQ  E+E    EL KK Q
Sbjct: 667  ENKIINIQLEESTKSIQKQIQDIKELSENLETQKQSAQEEIQKQKSELE----ELHKK-Q 721

Query: 857  ILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQT 916
            I    NQN    + +++  ++  VE+ N +         ++  + +LE + K++T + Q 
Sbjct: 722  IESINNQN-NTKIQELENSHSNKVEELNNS---------HKKLIEELEDSHKKVTEDIQH 771

Query: 917  LIVQKKKEIEDLEIEFNTQIESAIRDKKVLN----EKYE-KNIEYVTQLEAQLQEYKNNI 971
                + K+I+++  E   Q E +++++  L+    E+ E +  + +  LE Q++E  + +
Sbjct: 772  KNAHELKKIQEILSE-TQQREKSLQEQISLHSMGAEQQEVERQKIIKDLENQIKEKADQM 830

Query: 972  ENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINE---INKLNALLKQKDEEIIAL 1028
             NL   +E LN  N +    + +KQ  Q  D T++   +   INKL A L+   +  I L
Sbjct: 831  RNLEDQIELLNDQNSKQQADN-EKQNLQIQDLTQKEAQQQETINKLKADLENAKQ--IEL 887

Query: 1029 NQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQ 1088
            N  IN    ++   + + +  L+Q       +++E++  SK L DSK++  E  + +++Q
Sbjct: 888  N--INEQNEAFKKQLEESKQNLSQ-------LQKELEESSKNLSDSKENQNEEILSLKKQ 938

Query: 1089 DDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEE 1148
             + +  LK T+L    N   T    ++  I+ + ++    +                 + 
Sbjct: 939  IEDLLNLK-TELETSNNKINT----LNQEIDALKNEKQQKEEEYQKQINSLKDQSKNNDN 993

Query: 1149 EFIQERSVLQEQSAKLNTELQECYTKIIQL--ETLNTELTGHDV--VNQEQINQLKSKLE 1204
               QE  +L++Q+ KL  +L+E     +Q+  E  N E    D   +N++Q+N++    +
Sbjct: 994  NIQQETELLKQQNKKLEEQLKELKDSELQILEEIQNKEKEVDDFKQINEQQLNEINQLKD 1053

Query: 1205 QLNTENDNLLSTVAELRSSISSAVDQRG--FEIAELWKQHLAQREADFQKTEHELRVQLS 1262
            +L ++         E  +   S +D+    +E  EL  +   +     QK    L+ +  
Sbjct: 1054 ELASQKQK--DNQQEQETQGESQLDELKVKYEQVELDLKSKLEEINQLQKQNENLQREKL 1111

Query: 1263 AFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLR----NLQEKYADVIN 1318
             FE +   +   + S+    +N I+ +E  +++ +    +   L     N +EK  +   
Sbjct: 1112 DFEKEIADMKSQLNSTAFSSSNNIINLEN-SAMNDSTTPRNSSLVSTPVNNEEKKDNEDK 1170

Query: 1319 QIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLK 1378
            + E  + E +D+K                   +L+  ++  K+++++    + +EN QLK
Sbjct: 1171 KDEKDKKEEKDKKSK--EAKSDKQQTVKMTLEELKKWDEQVKELKKKR-KELEKENKQLK 1227

Query: 1379 KSSXXXXXXXXXXXXRVNDAEAKVLELTHQ-----LELKDSEIYQKTHEYTITLTQRN-D 1432
            +               +   E++  +L  Q     +EL++    Q++ +    L   + +
Sbjct: 1228 QELEEKSKQPVQNIDSLKQIESQKRQLEQQYMNLKIELEEKNKLQQSQQIKKNLNLESLE 1287

Query: 1433 EFENVRQQLVEYEKRIEDLTYEKESEL---AILRLKMHENANHYET-MQKESEIERVKLI 1488
            E   + Q L++ E  +     ++E E        L+   NA   E  +Q+ES  E+  L 
Sbjct: 1288 ERCRILQGLLD-ENSVNLQKADREREYWKEKYTGLQEDFNAKEEELKIQRESAREKFNLE 1346

Query: 1489 EELNVKITESVSLNKQVAEL-------------NKALEEEVAKTNEM----QTALENQEI 1531
              L  +I ++ SLNKQ+ E              N+ L++E AK  E+    Q  LEN+E 
Sbjct: 1347 MTLQSQIQQNSSLNKQIQEYERNLQAYKQLNADNENLKKECAKLRELVDKLQEELENKER 1406

Query: 1532 ----------EIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMN 1577
                      E+  LNDE     N +   S ++Q   S      Q    QL+++ N
Sbjct: 1407 NQEKLSHKLNELNELNDEYQKKINYLEKQSERLQNQKSELEQNLQSITTQLEDSQN 1462



 Score =  166 bits (403), Expect = 5e-39
 Identities = 233/1210 (19%), Positives = 517/1210 (42%), Gaps = 79/1210 (6%)

Query: 404  KNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGP 463
            K ++A+L++V     K+  +KE  + EK              D LI    ++ ++     
Sbjct: 11   KEQVAQLKVVTYEKVKETQEKEKQLEEKKQEIKKLQKEQD--DILIQLSTIDSEKQELEK 68

Query: 464  SLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDL-IEKLKSAEEQITQLNDEIDAA 522
             L  +    +     +   E L+QELN +    +  +L I  LK   +++    +EI + 
Sbjct: 69   ELQQLKEQQQQSQGNSSESEALQQELNKQKDKHSELELEINNLKDTNQKLQAKIEEIQS- 127

Query: 523  NKNMIKVKSNHKLKLKQMQKTIDNFSKVSDS-NKEIVRLTEELHHLSQKVAELEEEKGNL 581
            +K   +++ N K K+ ++   ID   + + S N ++  L  E+    Q++A+ E++   L
Sbjct: 128  HKYEEQIQQNEK-KIAELNSQIDKQDEENKSLNGKLQELESEIKSTHQQIAQKEQD---L 183

Query: 582  QLHLVDYDS---GRMIESDVYKKMIEMENLA-ETRLKAISLLESQKFDLVQELHILQQKY 637
            Q    D DS      +E +  KK ++++N       + ++ LE++  D        Q K 
Sbjct: 184  QKQKEDSDSLLEKTKLELEENKKQLDIKNQEINDANQKVNDLENKLKDSGSTNEEFQLKQ 243

Query: 638  DEVEDKLADISQLQSDQVCSEIKSVHLEEQID-ALSASKKELALVIENLKLDKEQLYGTI 696
             ++EDK   ISQ    +   + K   LE+++D AL   +     + + LK+ ++++    
Sbjct: 244  KDLEDK---ISQADETKQGLQNKLSELEKKLDQALKEKENAQKELQDQLKMKEDEVEQLK 300

Query: 697  KDLENDKEDIMNKLQNYIQEN----MDLTDKL----EKMSAEKISE--LLAKINHE--EQ 744
            KDL+  K+  + ++QN  Q+     + L +K+     K+S E  S+  L+ ++  +  + 
Sbjct: 301  KDLDQQKQQQIQEVQNLKQDQSKEVLTLQEKIGVLESKVSEETASKQKLIEEVEQKGKQV 360

Query: 745  SKIQTQFGI--DAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQL 802
            S++Q Q  +  +    ++D  +E    E+ + K +I  +++ I   E++  S    +++L
Sbjct: 361  SQLQDQINLIKEQSSSDQDKLMEQKNQEIKELKDQIENIQQKI---EEQTNSSNSLSEEL 417

Query: 803  GSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEEN 862
                +E +KA  ++ + E E       +   +  +E++  +I+    EL +K   + +++
Sbjct: 418  SQAKEELKKAQEQFQLSEKEKQTLKEQISQLNLQIEEKSTQIQEVQNELSQKLNEIAQKD 477

Query: 863  QNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKK 922
            + ++   S+     +   E     +    +  +   Q+ +L  N++    E+   +  K+
Sbjct: 478  EKIKHLESENTSSLSQSEELGKEFNEIREQMIQKDQQIDNLNVNIQAKEKEYNEQLQLKE 537

Query: 923  KEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELN 982
            KE  +   + N +I++       LNE+ +     + +    +Q+Y+N+IE L  N+E   
Sbjct: 538  KEYSEKLDKINEEIKNLNEVISQLNEENKIAKIQIEESNKSIQKYENDIEELKQNIETEK 597

Query: 983  KMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSM 1042
            K +   I +  +  + Q  D   Q I +I +L      + +EI     +++  Q    S+
Sbjct: 598  KQSENQITELQEIHKKQIEDINSQNIAKIQELENKNVNQVQEINNSQDQLHKLQEEIKSL 657

Query: 1043 VSDYESKLAQFTTKLEN--MEEEMQRVSKQLLDSKQHNEELQILVREQDDQI-KELKETK 1099
             ++  +KL     K+ N  +EE  + + KQ+ D K+ +E L+   +   ++I K+  E +
Sbjct: 658  -NEQIAKLND-ENKIINIQLEESTKSIQKQIQDIKELSENLETQKQSAQEEIQKQKSELE 715

Query: 1100 LTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQE 1159
               +  I        +   E  +  +N V+            L    E+   +    +Q 
Sbjct: 716  ELHKKQIESINNQNNTKIQELENSHSNKVEELNNSHKKLIEEL----EDSHKKVTEDIQH 771

Query: 1160 QSAKLNTELQECYTKIIQLE-TLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVA 1218
            ++A    ++QE  ++  Q E +L  +++ H +  ++Q  + +  ++ L  +       + 
Sbjct: 772  KNAHELKKIQEILSETQQREKSLQEQISLHSMGAEQQEVERQKIIKDLENQIKEKADQMR 831

Query: 1219 ELRSSISSAVDQRGFEIAELWKQH-----LAQREADFQKTEHELRVQL---SAFESKYEQ 1270
             L   I    DQ   + A+  KQ+     L Q+EA  Q+T ++L+  L      E    +
Sbjct: 832  NLEDQIELLNDQNSKQQADNEKQNLQIQDLTQKEAQQQETINKLKADLENAKQIELNINE 891

Query: 1271 LLDSVQSSTQEETNKIVTM-----EQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRS 1325
              ++ +   +E    +  +     E   +L +  +++ E + +L+++  D++N    L++
Sbjct: 892  QNEAFKKQLEESKQNLSQLQKELEESSKNLSDSKENQNEEILSLKKQIEDLLN----LKT 947

Query: 1326 EIE--DEKV-AFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSX 1382
            E+E  + K+                   + + +  S K   + +  NI +E   LK+ + 
Sbjct: 948  ELETSNNKINTLNQEIDALKNEKQQKEEEYQKQINSLKDQSKNNDNNIQQETELLKQQN- 1006

Query: 1383 XXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLV 1442
                        + D+E ++LE     E +  +  Q   +    + Q  DE  + +Q+  
Sbjct: 1007 ---KKLEEQLKELKDSELQILEEIQNKEKEVDDFKQINEQQLNEINQLKDELASQKQKDN 1063

Query: 1443 EYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKI-TESVSL 1501
            + E+  +      ES+L  L++K  +       +  +S++E +  +++ N  +  E +  
Sbjct: 1064 QQEQETQG-----ESQLDELKVKYEQ-----VELDLKSKLEEINQLQKQNENLQREKLDF 1113

Query: 1502 NKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFA 1561
             K++A++   L      ++     LEN  +   T     + +   V     K  +     
Sbjct: 1114 EKEIADMKSQLNSTAFSSSNNIINLENSAMNDSTTPRNSSLVSTPVNNEEKKDNEDKKDE 1173

Query: 1562 SDTKQGRDEQ 1571
             D K+ +D++
Sbjct: 1174 KDKKEEKDKK 1183



 Score =  122 bits (295), Expect = 6e-26
 Identities = 141/841 (16%), Positives = 360/841 (42%), Gaps = 37/841 (4%)

Query: 775  KSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHD 834
            K  +   +E +A ++   Y   ++  +    L+EK++   +   ++D+++ +L+ +    
Sbjct: 4    KEELAFFKEQVAQLKVVTYEKVKETQEKEKQLEEKKQEIKKLQKEQDDILIQLSTIDSEK 63

Query: 835  RVVEKQLLEIEHENKELQ---KKNQILLEENQNLQISLSDMQQHYNALVEKANR--TDLA 889
            + +EK+L +++ + ++ Q    +++ L +E    +   S+++   N L +   +    + 
Sbjct: 64   QELEKELQQLKEQQQQSQGNSSESEALQQELNKQKDKHSELELEINNLKDTNQKLQAKIE 123

Query: 890  ESESTKYQTQLRDLESNLKRITHEHQTLIVQKKK---EIEDLEIEFNTQIESAIRDKKVL 946
            E +S KY+ Q++  E  +  +  +      + K    ++++LE E  +  +   + ++ L
Sbjct: 124  EIQSHKYEEQIQQNEKKIAELNSQIDKQDEENKSLNGKLQELESEIKSTHQQIAQKEQDL 183

Query: 947  NEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQ 1006
             ++ E +   + + + +L+E K  ++  N   +E+N  N ++ D  ++ +   S    E+
Sbjct: 184  QKQKEDSDSLLEKTKLELEENKKQLDIKN---QEINDANQKVND--LENKLKDSGSTNEE 238

Query: 1007 YINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQR 1066
            +  +   L   + Q DE    L  K++  +      + + E+   +   +L+  E+E+++
Sbjct: 239  FQLKQKDLEDKISQADETKQGLQNKLSELEKKLDQALKEKENAQKELQDQLKMKEDEVEQ 298

Query: 1067 VSKQLLDSKQHN-EELQILVREQDDQIKELKETKLTFEMNIPK---TEGMIISST----- 1117
            + K L   KQ   +E+Q L ++Q  ++  L+E     E  + +   ++  +I        
Sbjct: 299  LKKDLDQQKQQQIQEVQNLKQDQSKEVLTLQEKIGVLESKVSEETASKQKLIEEVEQKGK 358

Query: 1118 -IEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKII 1176
             +  + D  N +              K QE +E   +   +Q++  +          ++ 
Sbjct: 359  QVSQLQDQINLIKEQSSSDQDKLMEQKNQEIKELKDQIENIQQKIEEQTNSSNSLSEELS 418

Query: 1177 QLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSIS---SAVDQRGF 1233
            Q +    +      +++++   LK ++ QLN + +   + + E+++ +S   + + Q+  
Sbjct: 419  QAKEELKKAQEQFQLSEKEKQTLKEQISQLNLQIEEKSTQIQEVQNELSQKLNEIAQKDE 478

Query: 1234 EIAELWKQH---LAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTME 1290
            +I  L  ++   L+Q E +  K  +E+R Q+   + + + L  ++Q+  +E   ++   E
Sbjct: 479  KIKHLESENTSSLSQSE-ELGKEFNEIREQMIQKDQQIDNLNVNIQAKEKEYNEQLQLKE 537

Query: 1291 QVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXX 1350
            +  S   KL    E ++NL E  + +  + +I + +IE+   +                 
Sbjct: 538  KEYS--EKLDKINEEIKNLNEVISQLNEENKIAKIQIEESNKSIQKYENDIEELKQNIET 595

Query: 1351 DLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLE 1410
            + +       ++QE     I + N+Q                  +N+++ ++ +L  +++
Sbjct: 596  EKKQSENQITELQEIHKKQIEDINSQNIAKIQELENKNVNQVQEINNSQDQLHKLQEEIK 655

Query: 1411 LKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKES-ELAILRLKMHEN 1469
              + +I +   E  I   Q  +  +++++Q+ + ++  E+L  +K+S +  I + K    
Sbjct: 656  SLNEQIAKLNDENKIINIQLEESTKSIQKQIQDIKELSENLETQKQSAQEEIQKQKSELE 715

Query: 1470 ANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQ 1529
              H + ++  +     K+ E  N    +   LN    +L + LE+   K  E        
Sbjct: 716  ELHKKQIESINNQNNTKIQELENSHSNKVEELNNSHKKLIEELEDSHKKVTE--DIQHKN 773

Query: 1530 EIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMN--KELLDAVPRA 1587
              E+  + + ++  Q   ++   +I  H   A   +  R + + +  N  KE  D +   
Sbjct: 774  AHELKKIQEILSETQQREKSLQEQISLHSMGAEQQEVERQKIIKDLENQIKEKADQMRNL 833

Query: 1588 E 1588
            E
Sbjct: 834  E 834



 Score = 88.2 bits (209), Expect = 2e-15
 Identities = 180/917 (19%), Positives = 391/917 (42%), Gaps = 97/917 (10%)

Query: 172  ILDLQEKINEK-DQI--IEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAM 228
            I DL+ +I EK DQ+  +E + +                    +D  Q+  + QE    +
Sbjct: 816  IKDLENQIKEKADQMRNLEDQIELLNDQNSKQQADNEKQNLQIQDLTQKEAQQQETINKL 875

Query: 229  EAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXX 288
            +A+ ++ KQ  L   E  +     LEE+ + L   + E+      L+   E         
Sbjct: 876  KADLENAKQIELNINEQNEAFKKQLEESKQNLSQLQKELEESSKNLSDSKENQNEEILSL 935

Query: 289  XXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENK 348
                    K+ IE     KTE+E   +     +  L ++I+ L++   + +Q  +E + +
Sbjct: 936  --------KKQIEDLLNLKTELETSNN----KINTLNQEIDALKN---EKQQKEEEYQKQ 980

Query: 349  LATMGTESKAVSSPSKKGSPLISRKSGR--NTASKMKSPWSQLSSETLNQDTD----KKI 402
            + ++  +SK   +  ++ + L+ +++ +      ++K    Q+  E  N++ +    K+I
Sbjct: 981  INSLKDQSKNNDNNIQQETELLKQQNKKLEEQLKELKDSELQILEEIQNKEKEVDDFKQI 1040

Query: 403  NKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEG 462
            N+ ++ +    I  L  +L  ++    +KD             D    +L+++++Q +E 
Sbjct: 1041 NEQQLNE----INQLKDELASQK----QKDNQQEQETQGESQLD----ELKVKYEQ-VE- 1086

Query: 463  PSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDV-NVKDLIEKLK-SAEEQITQL----- 515
               + + +  E++N++ K  E L++E  D  K++ ++K  +     S+   I  L     
Sbjct: 1087 ---LDLKSKLEEINQLQKQNENLQREKLDFEKEIADMKSQLNSTAFSSSNNIINLENSAM 1143

Query: 516  NDEIDAANKNMIKVKSNHKLKL--------KQMQKTIDNFSKVSDSNKE-IVRLT-EELH 565
            ND     N +++    N++ K         K  ++  D  SK + S+K+  V++T EEL 
Sbjct: 1144 NDSTTPRNSSLVSTPVNNEEKKDNEDKKDEKDKKEEKDKKSKEAKSDKQQTVKMTLEELK 1203

Query: 566  HLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFD 625
               ++V EL++++  L+               + +++ E        + ++  +ESQK  
Sbjct: 1204 KWDEQVKELKKKRKELEKE----------NKQLKQELEEKSKQPVQNIDSLKQIESQKRQ 1253

Query: 626  LVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENL 685
            L Q+   L+ + +E ++KL      QS Q+   +    LEE+   L     E ++ ++  
Sbjct: 1254 LEQQYMNLKIELEE-KNKLQ-----QSQQIKKNLNLESLEERCRILQGLLDENSVNLQKA 1307

Query: 686  KLDKE---QLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHE 742
              ++E   + Y  +++  N KE+ +   +   +E  +L   L+    +  S  L K   E
Sbjct: 1308 DREREYWKEKYTGLQEDFNAKEEELKIQRESAREKFNLEMTLQSQIQQNSS--LNKQIQE 1365

Query: 743  EQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQL 802
             +  +Q    ++A         EN++ E +K +  + +L+E +   E  +  L  K ++L
Sbjct: 1366 YERNLQAYKQLNADN-------ENLKKECAKLRELVDKLQEELENKERNQEKLSHKLNEL 1418

Query: 803  GSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEEN 862
                 E QK  +    Q + L N+ + L  + + +  QL + ++  K  QKK Q  + E 
Sbjct: 1419 NELNDEYQKKINYLEKQSERLQNQKSELEQNLQSITTQLEDSQNIQKINQKKYQNEVLEI 1478

Query: 863  QNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKK 922
            + ++  L    +      E       +  E+ K Q        N+   T +   +I++  
Sbjct: 1479 KQVRDGLVQQVKELKTKNESLENDVRSLREANKKQFH---STINVNPETAKKDKIILESL 1535

Query: 923  K-EIEDLEIEFNTQIESAIRDKK--VLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVE 979
                ++LE+ FN  + S   +K+  +L  + ++  + +  ++ Q++E    +E+    ++
Sbjct: 1536 SIRNQELEVNFNQNLISFKANKQIVILKVQSKQQKDKIEFMDKQIKEIHKVLESKIAIIQ 1595

Query: 980  ELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSY 1039
             L+K   EL  K+   +  +   Y ++ + E+ K   L+  K+ + +     I N ++  
Sbjct: 1596 NLSK---ELFHKNPTSEDIKD-IYEQKELQEV-KNYKLMNYKEIQDLIEKMSIENIRMRK 1650

Query: 1040 MSMVSDYESKLAQFTTK 1056
              ++   E K A  + K
Sbjct: 1651 NVLILGQELKEAMDSQK 1667


>UniRef50_Q22RF4 Cluster: Viral A-type inclusion protein repeat
            containing protein; n=1; Tetrahymena thermophila
            SB210|Rep: Viral A-type inclusion protein repeat
            containing protein - Tetrahymena thermophila SB210
          Length = 3640

 Score =  181 bits (441), Expect = 1e-43
 Identities = 305/1609 (18%), Positives = 696/1609 (43%), Gaps = 171/1609 (10%)

Query: 49   ERQIKFERAQKCLENAALVSKRIKEHRKATAELLGRPFVPGISESLANTLKQKEILMEKI 108
            E+ I+ +   +  +N  L S++I E ++   ELL R       E   N ++Q     + +
Sbjct: 1285 EQIIELKEEIRQQQNKYLESQKINEKKQKEIELLRREV-----EEFQNEIQQLTQRNQSL 1339

Query: 109  KQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNALSVLQVKMKIM 168
                +   +    +                    +    S+   E  + L + +++++  
Sbjct: 1340 NSRLQAQNQEINLLKNEKEEYNLLKHDQINENSSNQDRNSSESNEGTSDLELARMQIEGQ 1399

Query: 169  ETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQEN---- 224
            E  +  LQ  +  KD  I+  N+                    E   Q  ++++EN    
Sbjct: 1400 ERDLEKLQIDLRTKDSYIDEMNQENLMLKDKVNQQQQEIRYLQEQVSQLNSEIEENVQRQ 1459

Query: 225  --FIAME-AEWKDEKQRLLKDIESKDVRISSLE----EANKLLEAARFEISL---EHSKL 274
               I M+   +++E++++ K +E     +  L     + +  + +A  +I     E+ K 
Sbjct: 1460 DELIEMQKVNFENEREQMQKVLEENLEELKRLRNERGQTSDQVHSASKQIQFWQQEYEKA 1519

Query: 275  AQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHL 334
             QE E+              +  +S   S + + +IE +  +    + +  ++++  E +
Sbjct: 1520 QQECEKVLSDFNLLQREFQKIQAESDLKSAKLQKQIERQSRV----IFDQEQQLQQSERM 1575

Query: 335  NCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETL 394
            N   R ++K+ E++L     +S   +SP ++     ++    N   +    + QL +E  
Sbjct: 1576 NSSRRFSSKK-EDQL----NQSSLSNSPEREWQKKYNQLKEEN--EQFSRDYQQLINE-- 1626

Query: 395  NQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQL 454
            NQ   +++ K E + L++  +  N +L ++   + E ++           +   +A++Q 
Sbjct: 1627 NQRILEEVRKLEESCLQL--KERNSELDEENSSLREDNSALMQQVQQIKSQ---VAEIQQ 1681

Query: 455  EHQQHMEGPS---LIHVGTNTE-DVNEIA--KVQEQLKQELNDEIKDVNVKDLI-EKLKS 507
            +++Q  E  S   +++ GT  E  V++    +VQ++L+Q     I   N   ++ E++K 
Sbjct: 1682 QYEQQAEKESEYEMLYKGTQDELQVSKTINKQVQDKLRQVQQSLIDKENYCSILQEQIKE 1741

Query: 508  AEEQITQLNDEIDAANKNMIKVKSNHKLKLKQ-------MQKTIDNF------------S 548
                + ++ D+ D   KN+ K K++  + LKQ       M++ ++N             S
Sbjct: 1742 YNGVLQKMKDDEDNVEKNL-KEKTSEIIDLKQQMNLYIEMKQEMENQYKSKDEQLDVAES 1800

Query: 549  KVSDSNKEIVRLTEELHHLSQKVAELEE---EKGNLQLHLVDYDSGRMIE-SDVYKKMIE 604
            K+ ++ KE ++L +E+  LSQ   + E+   ++   QL+ ++ +   +I+ +D  +  I+
Sbjct: 1801 KLREAQKENLKLKQEVQKLSQSGNQQEDMLNQQDQQQLNTLEQEKQSLIDQNDQLRDQIQ 1860

Query: 605  MENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHL 664
              N        I  L  Q FD   ++  L  + +E +  + D+     DQ+ S+I+   L
Sbjct: 1861 QLN------SQIQDLSKQNFDFDNQIEDLNNRIEEKDRDIQDLQNRIGDQL-SQIQ--RL 1911

Query: 665  EEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKL 724
            +E +      +++  + I++++++K+Q    I+ LE   E + +++ N +Q  +D+ ++ 
Sbjct: 1912 KEDL----TQEEQKNVQIQSIQIEKDQ---KIQVLEEQAESLTDEITN-LQGQIDILNRQ 1963

Query: 725  EKMSAEKISELLAK----INHEEQSKIQTQFGIDAKIQERDLYIEN--IESELSKYKSRI 778
               S   +SE+       +N +++ +   Q   D + Q   L IEN  ++ ELS+ KS  
Sbjct: 1964 LNSSYNTLSEIQKNKQTFVNQDKELEKFQQIQADQQKQIDSLLIENEKLQQELSQQKSDF 2023

Query: 779  CRLEESIAVMEDRRYSL----ERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHD 834
               EES  ++  +   L    + K +QL +YL+EK     + +  ++E   RL   +   
Sbjct: 2024 ---EESQKMLNQQTVQLSEQAQHKQEQLKNYLEEKNTILVDNSNLKEE-TERLQQDLQKQ 2079

Query: 835  RVV----EKQLLEIEHE----NKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRT 886
             ++    E++++ +E       ++LQ+K +IL  + + +Q+ + +++Q    L++   + 
Sbjct: 2080 FIITARNEEKIIFLEQSMEQLKQDLQQKEEILESKEEIIQLKIEEIKQLEGKLLQHEEKI 2139

Query: 887  -----DLAESE--STKYQTQLRDLESNLKRITHEHQTLI---VQKKKEIEDLEI------ 930
                 D+ + E  S   + +++ LE  ++    + Q L+   + +    E L+I      
Sbjct: 2140 HQLQDDIWQKEENSQLLEEKIQQLEEKIQEYEEKIQNLVEDNISQNISQEQLQIQQKIID 2199

Query: 931  EFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELID 990
            E+  ++++++     L ++     + +  LE QL E +   E L  N +E+ +    LID
Sbjct: 2200 EYTQKLDASLEKAGELQKQITFKQQKIAILEKQLNEVEAENELLKQN-QEVREQEFALID 2258

Query: 991  KHVQ--KQQTQ------------SPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQ 1036
            + ++  K+Q Q            S +  EQ  ++       +++ ++++ +LNQ+   +Q
Sbjct: 2259 EQIKSHKEQIQNLKNQLQVSESKSKEKLEQNSDQKRNQQKKIEEYEQKLESLNQQFLQSQ 2318

Query: 1037 VSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELK 1096
              Y   ++    +L Q   K + + E + +  K + D + + ++L  LV EQ D+I EL 
Sbjct: 2319 NQYEDQINQCNQQLIQARNKEKQLNETISQNEKTIDDLRINIKDLNNLVYEQIDKINELT 2378

Query: 1097 ETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEF-IQERS 1155
            E +L  E     ++   +   +    +  +  +            LK ++E E  I +  
Sbjct: 2379 E-QLNQEREQFNSD---LQKEVLAKQEQESEFNSIKQQLHEQNDTLKKEKEREIQILKDQ 2434

Query: 1156 VLQEQSAKLNTELQECYTKIIQLETLNTELTGH-DVVNQEQINQLKSKLEQLNTENDNLL 1214
            +   +  K N EL     +  ++  L  ++  H D++N+  + Q ++K+ Q +      +
Sbjct: 2435 IEHLEKEKNNLELNIEKQREEEMSMLRAQIASHKDIINE--LRQERTKISQSDQSKAEEI 2492

Query: 1215 STVAELRSSISSAVDQRGFEIAELW-KQHLAQREA-DFQKTEHELRVQLSAFESKYEQLL 1272
              + +  + I    D+    + +L  K  + Q E  +  K  +E+ ++    E  ++   
Sbjct: 2493 QKLEQQLNQIKYDKDELQENVNQLQNKIDINQNEKNEISKMLNEVTLEKERKEKDFKNKE 2552

Query: 1273 DSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVIN----QIEILRSEIE 1328
            +++     EE  K++       LQ KL+  +  + NL++  AD+ +    +I I+R ++ 
Sbjct: 2553 ETLNQQLNEENRKVL------QLQEKLEKHQTEIANLRQNLADLSSSSQEEINIIREQLN 2606

Query: 1329 DEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXX 1388
             + +A                   +++  S    +EQ I+++  +N +L           
Sbjct: 2607 SQVIASNNNIQMLQDQIKQYQQKSQSDADSQILQREQKIVDLVNQNTELNNQLHEANTKI 2666

Query: 1389 XXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRI 1448
                 +    +A++ E    + LK+S++ ++  +      Q    F++ +  L + + ++
Sbjct: 2667 SQLNAKNQQEKARLEE---SITLKESQLEEQKEQQN----QLKLSFQHEKSILEKEKDQL 2719

Query: 1449 EDLTYEKESELAILRLKMHE-NANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAE 1507
                 ++  E++ L  K  E N    E  +K S+ +    +++ N K+ ES+   K+ + 
Sbjct: 2720 LQQISQQNDEISSLTQKETEFNEQKSEYQEKISKFKAQ--LDQTNAKLEESL---KEQSN 2774

Query: 1508 LNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQK 1556
            L + +  +   +N+  T +E+ + E+  LN+ I  +         +IQK
Sbjct: 2775 LKQQISLQNENSNQQNTKIEDLQTEVEQLNNLIKQINQKYLDLQHEIQK 2823



 Score =  177 bits (431), Expect = 2e-42
 Identities = 278/1484 (18%), Positives = 627/1484 (42%), Gaps = 123/1484 (8%)

Query: 153  EKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXE 212
            E D   + LQ +++     I D ++++ + +++  ++  ++                   
Sbjct: 1543 ESDLKSAKLQKQIERQSRVIFDQEQQLQQSERMNSSRRFSSKKEDQLNQSSLSNSPEREW 1602

Query: 213  DTK-QQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271
              K  Q+ +  E F     +  +E QR+L+++   +     L+E N  L+     +  ++
Sbjct: 1603 QKKYNQLKEENEQFSRDYQQLINENQRILEEVRKLEESCLQLKERNSELDEENSSLREDN 1662

Query: 272  SKLAQELEQXXXXXXXXXXXXXXLAKQSIE-----PSCEEKTEIEEKGSLEIANMTELTK 326
            S L Q+++Q               A++  E        +++ ++ +  + ++ +     +
Sbjct: 1663 SALMQQVQQIKSQVAEIQQQYEQQAEKESEYEMLYKGTQDELQVSKTINKQVQDKLRQVQ 1722

Query: 327  KIELLEHLNCQIRQTN-KELENKLATMGTESKAVSSPSK-KGSPLISRKSGRNTASKMKS 384
            +  + +   C I Q   KE    L  M  +   V    K K S +I  K   N   +MK 
Sbjct: 1723 QSLIDKENYCSILQEQIKEYNGVLQKMKDDEDNVEKNLKEKTSEIIDLKQQMNLYIEMKQ 1782

Query: 385  PW-SQLSSETLNQD-TDKKIN--KNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXX 440
               +Q  S+    D  + K+   + E  KL+  +Q L++    +E +++++D        
Sbjct: 1783 EMENQYKSKDEQLDVAESKLREAQKENLKLKQEVQKLSQSGNQQEDMLNQQDQQQLNTLE 1842

Query: 441  XXXGKDTLIAQL-QLEHQQHMEGPSLIHVGTNTEDV-NEIAKVQEQLKQELNDEIKDVNV 498
                K +LI Q  QL  Q       +  +     D  N+I  +  ++++      KD ++
Sbjct: 1843 QE--KQSLIDQNDQLRDQIQQLNSQIQDLSKQNFDFDNQIEDLNNRIEE------KDRDI 1894

Query: 499  KDLIEKLKSAEEQITQLNDEIDAANKNMIKVKS---NHKLKLKQMQKTIDNFS-KVSDSN 554
            +DL  ++     QI +L +++    +  ++++S       K++ +++  ++ + ++++  
Sbjct: 1895 QDLQNRIGDQLSQIQRLKEDLTQEEQKNVQIQSIQIEKDQKIQVLEEQAESLTDEITNLQ 1954

Query: 555  KEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLK 614
             +I  L  +L+     ++E+++ K        + +  + I++D  K   ++++L     K
Sbjct: 1955 GQIDILNRQLNSSYNTLSEIQKNKQTFVNQDKELEKFQQIQADQQK---QIDSLLIENEK 2011

Query: 615  AISLLESQKFDLVQELHILQQK----YDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDA 670
                L  QK D  +   +L Q+     ++ + K   +     ++    + + +L+E+ + 
Sbjct: 2012 LQQELSQQKSDFEESQKMLNQQTVQLSEQAQHKQEQLKNYLEEKNTILVDNSNLKEETER 2071

Query: 671  LSAS-KKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSA 729
            L    +K+  +   N    +E++    + +E  K+D+  K     +E ++  +++ ++  
Sbjct: 2072 LQQDLQKQFIITARN----EEKIIFLEQSMEQLKQDLQQK-----EEILESKEEIIQLKI 2122

Query: 730  EKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVME 789
            E+I +L  K+   E+   Q Q  I  K +   L    +E ++ + + +I   EE I  + 
Sbjct: 2123 EEIKQLEGKLLQHEEKIHQLQDDIWQKEENSQL----LEEKIQQLEEKIQEYEEKIQNLV 2178

Query: 790  DRRYSLERKADQLGSYLQEKQKAYSEYTIQED-------ELVNRLAVLMDHDRVVEKQLL 842
            +   S     +Q    LQ +QK   EYT + D       EL  ++        ++EKQL 
Sbjct: 2179 EDNISQNISQEQ----LQIQQKIIDEYTQKLDASLEKAGELQKQITFKQQKIAILEKQLN 2234

Query: 843  EIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRD 902
            E+E EN EL K+NQ + E  Q   +    ++ H   +    N+  ++ES+S +   Q  D
Sbjct: 2235 EVEAEN-ELLKQNQEVRE--QEFALIDEQIKSHKEQIQNLKNQLQVSESKSKEKLEQNSD 2291

Query: 903  LESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEA 962
             + N ++   E++    QK + +    ++   Q E  I      N++  +      QL  
Sbjct: 2292 QKRNQQKKIEEYE----QKLESLNQQFLQSQNQYEDQINQ---CNQQLIQARNKEKQLNE 2344

Query: 963  QLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKD 1022
             + + +  I++L +N+++LN +  E IDK + +   Q     EQ+ +++ K   L KQ+ 
Sbjct: 2345 TISQNEKTIDDLRINIKDLNNLVYEQIDK-INELTEQLNQEREQFNSDLQK-EVLAKQEQ 2402

Query: 1023 E-EIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEEL 1081
            E E  ++ Q+++       ++  + E ++     ++E++E+E   +  +L   KQ  EE+
Sbjct: 2403 ESEFNSIKQQLHEQN---DTLKKEKEREIQILKDQIEHLEKEKNNL--ELNIEKQREEEM 2457

Query: 1082 QIL---VREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXX 1138
             +L   +    D I EL++ +     +  +++   I    + ++    + D         
Sbjct: 2458 SMLRAQIASHKDIINELRQERTKISQS-DQSKAEEIQKLEQQLNQIKYDKDELQENVNQL 2516

Query: 1139 XXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQ 1198
               + + + E+   E S +  +   L  E +E   K  + ETLN +L   +     ++ Q
Sbjct: 2517 QNKIDINQNEK--NEISKMLNE-VTLEKERKEKDFKNKE-ETLNQQLNEEN----RKVLQ 2568

Query: 1199 LKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELR 1258
            L+ KLE+  TE  NL   +A+L SS    ++        + ++ L  +          L+
Sbjct: 2569 LQEKLEKHQTEIANLRQNLADLSSSSQEEIN--------IIREQLNSQVIASNNNIQMLQ 2620

Query: 1259 VQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNL----QEKYA 1314
             Q+  ++ K +   DS     Q E   +  + Q T L N+L +    +  L    Q++ A
Sbjct: 2621 DQIKQYQQKSQSDADS--QILQREQKIVDLVNQNTELNNQLHEANTKISQLNAKNQQEKA 2678

Query: 1315 DVINQIEILRSEIEDE-------KVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSI 1367
             +   I +  S++E++       K++F                 +  +N     + ++  
Sbjct: 2679 RLEESITLKESQLEEQKEQQNQLKLSFQHEKSILEKEKDQLLQQISQQNDEISSLTQKE- 2737

Query: 1368 LNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQ---KTHEYT 1424
               NE+ ++ ++              ++ ++  +   L  Q+ L++    Q   K  +  
Sbjct: 2738 TEFNEQKSEYQEKISKFKAQLDQTNAKLEESLKEQSNLKQQISLQNENSNQQNTKIEDLQ 2797

Query: 1425 ITLTQRNDEFENVRQQLVEYEKRIEDLTYEK---ESELAILRLKMHENANHYETMQKESE 1481
              + Q N+  + + Q+ ++ +  I+   +EK   + E+   +         YE  Q + E
Sbjct: 2798 TEVEQLNNLIKQINQKYLDLQHEIQKEKFEKANLQKEITHCKEDYQIVQQKYENFQAQHE 2857

Query: 1482 IERVKLIEELNVKITESVSLNKQVAE--LNKALEEEVAKTNEMQTALENQEIEIVTLNDE 1539
             +++KLI+  + +  ES  L KQ  +    K ++ +    ++ +  ++ ++ +I  L DE
Sbjct: 2858 -DQLKLIKSTHAQ--ESAHLKKQYQQEFQQKLIDTQKDLQSKHEVEIKQKDEQISKLQDE 2914

Query: 1540 ITNLQNMVRASSSKIQKHVSFASDTKQG--RDEQLDNTMNKELL 1581
            +T  +  +      I ++     + KQ   +++QL+  +  +LL
Sbjct: 2915 LTQYKLNLEEQKQLITQNDKQVQELKQNIEQEKQLNQDLQNQLL 2958



 Score =  161 bits (391), Expect = 1e-37
 Identities = 277/1348 (20%), Positives = 581/1348 (43%), Gaps = 153/1348 (11%)

Query: 237  QRLLKDI---ESKDVRISSLE----EANKLLEAARFEISLEHSKLAQELEQXXXXXXXXX 289
            QRL +D+   E K+V+I S++    +  ++LE     ++ E + L  +++          
Sbjct: 1909 QRLKEDLTQEEQKNVQIQSIQIEKDQKIQVLEEQAESLTDEITNLQGQIDILNRQLNSSY 1968

Query: 290  XXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKL 349
                 + K   +    +  E+E+   ++     ++   +   E L  ++ Q   + E   
Sbjct: 1969 NTLSEIQKNK-QTFVNQDKELEKFQQIQADQQKQIDSLLIENEKLQQELSQQKSDFEESQ 2027

Query: 350  ATMGTESKAVSSPSK-KGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKI-----N 403
              +  ++  +S  ++ K   L +    +NT     S   +  +E L QD  K+      N
Sbjct: 2028 KMLNQQTVQLSEQAQHKQEQLKNYLEEKNTILVDNSNLKE-ETERLQQDLQKQFIITARN 2086

Query: 404  KNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGP 463
            + +I  LE  ++ L +DL  KE ++  K+                I QL++E  + +EG 
Sbjct: 2087 EEKIIFLEQSMEQLKQDLQQKEEILESKEE---------------IIQLKIEEIKQLEGK 2131

Query: 464  SLIHVGTNTEDVNEIAKVQEQLKQ-ELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAA 522
             L H         +I ++Q+ + Q E N ++ +  ++ L EK++  EE+I  L ++  + 
Sbjct: 2132 LLQHE-------EKIHQLQDDIWQKEENSQLLEEKIQQLEEKIQEYEEKIQNLVEDNISQ 2184

Query: 523  NKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNL- 581
            N +  +++   K+  +  QK   +  K  +  K+I    +++  L +++ E+E E   L 
Sbjct: 2185 NISQEQLQIQQKIIDEYTQKLDASLEKAGELQKQITFKQQKIAILEKQLNEVEAENELLK 2244

Query: 582  QLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQK-YDEV 640
            Q   V      +I+  +     +++NL + +L+       +K +   +    QQK  +E 
Sbjct: 2245 QNQEVREQEFALIDEQIKSHKEQIQNL-KNQLQVSESKSKEKLEQNSDQKRNQQKKIEEY 2303

Query: 641  EDKLADISQ--LQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKD 698
            E KL  ++Q  LQS     +  +   ++ I A +  K+    + +N K        TI D
Sbjct: 2304 EQKLESLNQQFLQSQNQYEDQINQCNQQLIQARNKEKQLNETISQNEK--------TIDD 2355

Query: 699  LENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHE-EQSKIQTQFGIDAKI 757
            L  + +D    L N + E +D           KI+EL  ++N E EQ     Q  + AK 
Sbjct: 2356 LRINIKD----LNNLVYEQID-----------KINELTEQLNQEREQFNSDLQKEVLAK- 2399

Query: 758  QERDLYIENIESELSKYKSRICRLEE-SIAVMEDRRYSLERKADQLGSYLQEKQKAYSEY 816
            QE++    +I+ +L +    + + +E  I +++D+   LE++ + L   + EKQ+     
Sbjct: 2400 QEQESEFNSIKQQLHEQNDTLKKEKEREIQILKDQIEHLEKEKNNLELNI-EKQR----- 2453

Query: 817  TIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHY 876
               E+E+    A +  H  ++     E+  E  ++ + +Q   EE Q L+  L+ ++   
Sbjct: 2454 ---EEEMSMLRAQIASHKDIIN----ELRQERTKISQSDQSKAEEIQKLEQQLNQIKYDK 2506

Query: 877  NALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQI 936
            + L E  N+    +++    Q +  ++   L  +T E +    +K+K+ ++ E   N Q+
Sbjct: 2507 DELQENVNQL---QNKIDINQNEKNEISKMLNEVTLEKE----RKEKDFKNKEETLNQQL 2559

Query: 937  ESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNI-ENLNMNVEELNKMNLELIDKHVQK 995
                R    L EK EK+   +  L   L +  ++  E +N+  E+LN   +   + ++Q 
Sbjct: 2560 NEENRKVLQLQEKLEKHQTEIANLRQNLADLSSSSQEEINIIREQLNSQVIAS-NNNIQM 2618

Query: 996  QQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTT 1055
             Q Q   Y ++  ++ +      +QK  +++  N ++NN        + +  +K++Q   
Sbjct: 2619 LQDQIKQYQQKSQSDADSQILQREQKIVDLVNQNTELNN-------QLHEANTKISQLNA 2671

Query: 1056 KLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIIS 1115
            K  N +E+ +      L   Q  E+     +EQ +Q+K         E +I + E   + 
Sbjct: 2672 K--NQQEKARLEESITLKESQLEEQ-----KEQQNQLK----LSFQHEKSILEKEKDQLL 2720

Query: 1116 STIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKI 1175
              I   +D+ +++                Q+E EF +++S  QE+ +K   +L +   K+
Sbjct: 2721 QQISQQNDEISSL---------------TQKETEFNEQKSEYQEKISKFKAQLDQTNAKL 2765

Query: 1176 IQLETLNTELTGHDVVNQEQINQLKSKLEQLNTEND---NLLSTVAELRSSISSAVDQRG 1232
             +     + L     +  E  NQ  +K+E L TE +   NL+  + +    +   + +  
Sbjct: 2766 EESLKEQSNLKQQISLQNENSNQQNTKIEDLQTEVEQLNNLIKQINQKYLDLQHEIQKEK 2825

Query: 1233 FEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQV 1292
            FE A L K+ +   + D+Q  +     +   F++++E  L  ++S+  +E+  +    Q 
Sbjct: 2826 FEKANLQKE-ITHCKEDYQIVQQ----KYENFQAQHEDQLKLIKSTHAQESAHLKKQYQ- 2879

Query: 1293 TSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDL 1352
               Q KL D +   ++LQ K+   I Q +   S+++DE   +                 +
Sbjct: 2880 QEFQQKLIDTQ---KDLQSKHEVEIKQKDEQISKLQDELTQYKLNLEEQKQLITQNDKQV 2936

Query: 1353 RTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELK 1412
            +   Q+ +Q ++   LN + +N  L++              +V     ++++ TH +   
Sbjct: 2937 QELKQNIEQEKQ---LNQDLQNQLLQQEK---YLHKKIDEIQVLKKSQELIQSTHSINDH 2990

Query: 1413 DSEIYQKTHEYTITLT-QRNDEFENVRQQ----LVEYEKRIEDL--TYEKESELAILRLK 1465
            ++   +  ++ + T++  R  + E+ R+     +++Y+K IE+L     +E E   L  +
Sbjct: 2991 NTATLRSDNDISPTMSLGRAKKVESYREDQDKIILQYKKEIENLQSLLNQEKEKCNLLNE 3050

Query: 1466 MHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTA 1525
              +     E   +  E  +    E+ + +I   +S N+++ + N+ L+EE  K  E  + 
Sbjct: 3051 EIKLKVQAEAPMQRRENNQETSAEKDHYQIL--ISQNQRLIQENQRLKEENDKLKEEYSY 3108

Query: 1526 LENQEIEIVTLNDEITNLQNMVRASSSK 1553
              +  + +   N    + QN    S+SK
Sbjct: 3109 YADNSVTLQQTNP--VSGQNTASQSASK 3134



 Score =  154 bits (373), Expect = 2e-35
 Identities = 297/1438 (20%), Positives = 604/1438 (42%), Gaps = 154/1438 (10%)

Query: 212  EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEIS--- 268
            +D  +Q+ K Q N I  + E   +    LK+I+S    I S  +  +LL   + + +   
Sbjct: 1085 KDLIKQIDKSQIN-IDQQRETISQLNFKLKEIQSNYEGIYSKLKQQELLSNQQLDENSKN 1143

Query: 269  -LEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCE---EKTEIEEKGSLEIANMTEL 324
             +++ K+  E E+                 Q  + + +   E +++++K  L+  ++ + 
Sbjct: 1144 NMDYQKIINEYEEKLNKTQIKLNQVFDEKLQIEQNNLDTQKELSQLQQKFRLQQESLQQK 1203

Query: 325  TKKIE--------LLEHLNCQIR-QTNKELENKLATMGTESKAVSSPSKKGSPLISRKSG 375
             K+IE         LE L+ QI+ Q NK  E  +     + +  SS S   S    +   
Sbjct: 1204 QKEIEDEKRSFAGKLEKLDQQIQNQKNKLNEKDMTIKRLQFELQSSQSLNDSLNEIQSKQ 1263

Query: 376  RNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLE---MVIQSLN-KDLVDKEYVISEK 431
            + TA   +    Q  SE LN++   ++ K EI + +   +  Q +N K   + E +  E 
Sbjct: 1264 KRTAYDDRQMLKQYESEDLNEEQIIEL-KEEIRQQQNKYLESQKINEKKQKEIELLRREV 1322

Query: 432  DTXXXXXXXXXXGKDTLIAQLQLEHQQH--MEGPSLIHVGTNTEDVNEIAKVQEQLKQEL 489
            +              +L ++LQ ++Q+   ++     +     + +NE +  Q++   E 
Sbjct: 1323 EEFQNEIQQLTQRNQSLNSRLQAQNQEINLLKNEKEEYNLLKHDQINENSSNQDRNSSES 1382

Query: 490  NDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNM-IKVKSNHKLKLKQMQKTIDNFS 548
            N+   D+ +  +  +++  E  + +L  +ID   K+  I   +   L LK          
Sbjct: 1383 NEGTSDLELARM--QIEGQERDLEKL--QIDLRTKDSYIDEMNQENLMLKD--------- 1429

Query: 549  KVSDSNKEIVRLTEELHHLSQKVAELEEEKGNL-QLHLVDYDSGRMIESDVYKKMIEMEN 607
            KV+   +EI  L E++  L+ ++ E  + +  L ++  V++++    E +  +K++E EN
Sbjct: 1430 KVNQQQQEIRYLQEQVSQLNSEIEENVQRQDELIEMQKVNFEN----EREQMQKVLE-EN 1484

Query: 608  LAETRLKAISLLESQKFDLV----QELHILQQKYD----EVEDKLADISQLQSD----QV 655
            L E  LK +     Q  D V    +++   QQ+Y+    E E  L+D + LQ +    Q 
Sbjct: 1485 LEE--LKRLRNERGQTSDQVHSASKQIQFWQQEYEKAQQECEKVLSDFNLLQREFQKIQA 1542

Query: 656  CSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQ 715
             S++KS  L++QI+     ++   +  +  +L + +   + +   + KED +N+      
Sbjct: 1543 ESDLKSAKLQKQIE-----RQSRVIFDQEQQLQQSERMNSSRRFSSKKEDQLNQ------ 1591

Query: 716  ENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYK 775
                L++  E+   +K ++L  + N +     Q     + +I E    +  +E    + K
Sbjct: 1592 --SSLSNSPEREWQKKYNQLKEE-NEQFSRDYQQLINENQRILEE---VRKLEESCLQLK 1645

Query: 776  SRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDR 835
             R   L+E  + + +   +L ++  Q+ S + E Q+ Y +   +E E         D  +
Sbjct: 1646 ERNSELDEENSSLREDNSALMQQVQQIKSQVAEIQQQYEQQAEKESEYEMLYKGTQDELQ 1705

Query: 836  VVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKA-NRTDLAESEST 894
            V +    +++ + +++Q+     L + +N    L +  + YN +++K  +  D  E    
Sbjct: 1706 VSKTINKQVQDKLRQVQQS----LIDKENYCSILQEQIKEYNGVLQKMKDDEDNVEKNLK 1761

Query: 895  KYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNI 954
            +  +++ DL+  +       Q +  Q K + E L++      ES +R+ +  N K ++ +
Sbjct: 1762 EKTSEIIDLKQQMNLYIEMKQEMENQYKSKDEQLDVA-----ESKLREAQKENLKLKQEV 1816

Query: 955  EYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKL 1014
            + ++Q   Q ++  N  +   +N  E  K +L  ID     Q  Q  D  +Q  ++I  L
Sbjct: 1817 QKLSQSGNQQEDMLNQQDQQQLNTLEQEKQSL--ID-----QNDQLRDQIQQLNSQIQDL 1869

Query: 1015 NALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDS 1074
            +      D +I  LN +I         + +    +L+Q           +QR+ + L   
Sbjct: 1870 SKQNFDFDNQIEDLNNRIEEKDRDIQDLQNRIGDQLSQ-----------IQRLKEDLTQE 1918

Query: 1075 KQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMI------ISSTIEPMSDDANNV 1128
            +Q N ++Q +  E+D +I+ L+E   +    I   +G I      ++S+   +S+   N 
Sbjct: 1919 EQKNVQIQSIQIEKDQKIQVLEEQAESLTDEITNLQGQIDILNRQLNSSYNTLSEIQKNK 1978

Query: 1129 DXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLET-LNTELTG 1187
                          ++Q +++  Q  S+L E   KL  EL +  +   + +  LN +   
Sbjct: 1979 QTFVNQDKELEKFQQIQADQQK-QIDSLLIENE-KLQQELSQQKSDFEESQKMLNQQTVQ 2036

Query: 1188 HDVVNQEQINQLKSKLEQLNT---ENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLA 1244
                 Q +  QLK+ LE+ NT   +N NL      L+  +     Q+ F I    ++ + 
Sbjct: 2037 LSEQAQHKQEQLKNYLEEKNTILVDNSNLKEETERLQQDL-----QKQFIITARNEEKII 2091

Query: 1245 QREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEE 1304
              E   ++ + +L+ +    ESK E +   ++   Q E   +   E++  LQ+ +  KEE
Sbjct: 2092 FLEQSMEQLKQDLQQKEEILESKEEIIQLKIEEIKQLEGKLLQHEEKIHQLQDDIWQKEE 2151

Query: 1305 HLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQE 1364
            + + L+EK    I Q+E    E E EK+                    +     Y Q  +
Sbjct: 2152 NSQLLEEK----IQQLEEKIQEYE-EKIQNLVEDNISQNISQEQLQIQQKIIDEYTQKLD 2206

Query: 1365 QSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYT 1424
             S+    E+  +L+K              ++N+ EA+   L    E+++ E      +  
Sbjct: 2207 ASL----EKAGELQKQITFKQQKIAILEKQLNEVEAENELLKQNQEVREQEFALIDEQ-- 2260

Query: 1425 ITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIER 1484
              +    ++ +N++ QL   E + ++              K+ +N++     QK+ E E 
Sbjct: 2261 --IKSHKEQIQNLKNQLQVSESKSKE--------------KLEQNSDQKRNQQKKIE-EY 2303

Query: 1485 VKLIEELNVKITESVS-LNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNL 1543
             + +E LN +  +S +    Q+ + N+ L +   K  ++   +   E  I  L   I +L
Sbjct: 2304 EQKLESLNQQFLQSQNQYEDQINQCNQQLIQARNKEKQLNETISQNEKTIDDLRINIKDL 2363

Query: 1544 QNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELL-DAVPRAELDLAMYMLHQRD 1600
             N+V     KI +         Q R EQ ++ + KE+L      +E +     LH+++
Sbjct: 2364 NNLVYEQIDKINE---LTEQLNQER-EQFNSDLQKEVLAKQEQESEFNSIKQQLHEQN 2417



 Score =  144 bits (350), Expect = 1e-32
 Identities = 273/1450 (18%), Positives = 619/1450 (42%), Gaps = 93/1450 (6%)

Query: 164  KMKIMETTILDLQEKINEKDQII---EAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTK 220
            K++ ++  I + + K+NEKD  I   + + +++                   D +Q + +
Sbjct: 1217 KLEKLDQQIQNQKNKLNEKDMTIKRLQFELQSSQSLNDSLNEIQSKQKRTAYDDRQMLKQ 1276

Query: 221  MQENFIAME--AEWKDE-KQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQE 277
             +   +  E   E K+E +Q+  K +ES+ +     +E  +LL     E   E  +L Q 
Sbjct: 1277 YESEDLNEEQIIELKEEIRQQQNKYLESQKINEKKQKEI-ELLRREVEEFQNEIQQLTQR 1335

Query: 278  LEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQ 337
             +               L  +  E +  +  +I E  S +  N +E  +    LE    Q
Sbjct: 1336 NQSLNSRLQAQNQEINLLKNEKEEYNLLKHDQINENSSNQDRNSSESNEGTSDLELARMQ 1395

Query: 338  IRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASK-MKSPWSQLSSE---- 392
            I    ++LE     + T+   +   +++   L  + + +    + ++   SQL+SE    
Sbjct: 1396 IEGQERDLEKLQIDLRTKDSYIDEMNQENLMLKDKVNQQQQEIRYLQEQVSQLNSEIEEN 1455

Query: 393  TLNQD---TDKKIN-KNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTL 448
               QD     +K+N +NE  +++ V++   ++L        +                  
Sbjct: 1456 VQRQDELIEMQKVNFENEREQMQKVLEENLEELKRLRNERGQTSDQVHSASKQIQFWQQE 1515

Query: 449  IAQLQLEHQQHMEGPSLIH---VGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKL 505
              + Q E ++ +   +L+         E   + AK+Q+Q++++              E++
Sbjct: 1516 YEKAQQECEKVLSDFNLLQREFQKIQAESDLKSAKLQKQIERQSRVIFDQEQQLQQSERM 1575

Query: 506  KSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSK-VSDSNKEIVRLTEEL 564
             S+    ++  D+++ ++ +    +   K K  Q+++  + FS+       E  R+ EE+
Sbjct: 1576 NSSRRFSSKKEDQLNQSSLSNSPEREWQK-KYNQLKEENEQFSRDYQQLINENQRILEEV 1634

Query: 565  HHLSQKVAELEEEKGNL---QLHLVDYDSGRMIESDVYKKMI-EMENLAETRLKAISLLE 620
              L +   +L+E    L      L + +S  M +    K  + E++   E + +  S  E
Sbjct: 1635 RKLEESCLQLKERNSELDEENSSLREDNSALMQQVQQIKSQVAEIQQQYEQQAEKESEYE 1694

Query: 621  SQKFDLVQELHILQQKYDEVEDKLADISQ--LQSDQVCSEIKSVHLEEQIDALSASKKEL 678
                    EL + +    +V+DKL  + Q  +  +  CS I    ++E    L   K + 
Sbjct: 1695 MLYKGTQDELQVSKTINKQVQDKLRQVQQSLIDKENYCS-ILQEQIKEYNGVLQKMKDDE 1753

Query: 679  ALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQ---ENMDLTD-KLEKMSAEKISE 734
              V +NLK +K      +K   N   ++  +++N  +   E +D+ + KL +   E + +
Sbjct: 1754 DNVEKNLK-EKTSEIIDLKQQMNLYIEMKQEMENQYKSKDEQLDVAESKLREAQKENL-K 1811

Query: 735  LLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESEL----SKYKSRICRLEESIAVMED 790
            L  ++    QS  Q +  ++ + Q++   +E  +  L     + + +I +L   I  +  
Sbjct: 1812 LKQEVQKLSQSGNQQEDMLNQQDQQQLNTLEQEKQSLIDQNDQLRDQIQQLNSQIQDLSK 1871

Query: 791  RRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKE 850
            + +  + + + L + ++EK +   +   +  + ++++  L +     E++ ++I+    E
Sbjct: 1872 QNFDFDNQIEDLNNRIEEKDRDIQDLQNRIGDQLSQIQRLKEDLTQEEQKNVQIQSIQIE 1931

Query: 851  LQKKNQILLEENQNLQISLSDMQQHYNALVEKANRT--DLAESESTK--YQTQLRDLESN 906
              +K Q+L E+ ++L   ++++Q   + L  + N +   L+E +  K  +  Q ++LE  
Sbjct: 1932 KDQKIQVLEEQAESLTDEITNLQGQIDILNRQLNSSYNTLSEIQKNKQTFVNQDKELE-K 1990

Query: 907  LKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQE 966
             ++I  + Q  I     E E L+ E + Q       +K+LN++  +  E     + QL+ 
Sbjct: 1991 FQQIQADQQKQIDSLLIENEKLQQELSQQKSDFEESQKMLNQQTVQLSEQAQHKQEQLKN 2050

Query: 967  Y---KNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYI---NEINKLNALLKQ 1020
            Y   KN I   N N++E      E + + +QKQ   +    E+ I     + +L   L+Q
Sbjct: 2051 YLEEKNTILVDNSNLKE----ETERLQQDLQKQFIITARNEEKIIFLEQSMEQLKQDLQQ 2106

Query: 1021 KDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEM--QRVSKQLLDSKQHN 1078
            K EEI+   ++I   ++     +   E KL Q   K+  +++++  +  + QLL+ K   
Sbjct: 2107 K-EEILESKEEIIQLKI---EEIKQLEGKLLQHEEKIHQLQDDIWQKEENSQLLEEK--I 2160

Query: 1079 EELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSD--DANNVDXXXXXXX 1136
            ++L+  ++E +++I+ L E  ++   NI + +  I    I+  +   DA+          
Sbjct: 2161 QQLEEKIQEYEEKIQNLVEDNIS--QNISQEQLQIQQKIIDEYTQKLDASLEKAGELQKQ 2218

Query: 1137 XXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQI 1196
                  K+   E+ + E    + +  K N E++E    +I  +  + +    ++ NQ Q+
Sbjct: 2219 ITFKQQKIAILEKQLNEVEA-ENELLKQNQEVREQEFALIDEQIKSHKEQIQNLKNQLQV 2277

Query: 1197 NQLKS--KLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTE 1254
            ++ KS  KLEQ + +  N    + E    + S ++Q+  +    ++  + Q      +  
Sbjct: 2278 SESKSKEKLEQNSDQKRNQQKKIEEYEQKLES-LNQQFLQSQNQYEDQINQCNQQLIQAR 2336

Query: 1255 HELRVQLSAFESKYEQLLDSVQSSTQEETNKIV-TMEQVTSLQNKL-QDKEEHLRNLQEK 1312
            ++ + QL+   S+ E+ +D ++ + ++  N +   ++++  L  +L Q++E+   +LQ++
Sbjct: 2337 NKEK-QLNETISQNEKTIDDLRINIKDLNNLVYEQIDKINELTEQLNQEREQFNSDLQKE 2395

Query: 1313 Y---ADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYK-QMQEQSIL 1368
                 +  ++   ++ ++ ++                     L  E  + +  +++Q   
Sbjct: 2396 VLAKQEQESEFNSIKQQLHEQNDTLKKEKEREIQILKDQIEHLEKEKNNLELNIEKQREE 2455

Query: 1369 NINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLT 1428
             ++   AQ+  S             +++ ++    E   +LE + ++I     E    + 
Sbjct: 2456 EMSMLRAQI-ASHKDIINELRQERTKISQSDQSKAEEIQKLEQQLNQIKYDKDELQENVN 2514

Query: 1429 QRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLI 1488
            Q  ++ +  + +  E  K + ++T EKE        K  +  N  ET+ ++   E  K++
Sbjct: 2515 QLQNKIDINQNEKNEISKMLNEVTLEKER-------KEKDFKNKEETLNQQLNEENRKVL 2567

Query: 1489 ---EELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQN 1545
               E+L    TE  +L + +A+L+ + +EE+   N ++  L +Q   ++  N+ I  LQ+
Sbjct: 2568 QLQEKLEKHQTEIANLRQNLADLSSSSQEEI---NIIREQLNSQ---VIASNNNIQMLQD 2621

Query: 1546 MVRASSSKIQ 1555
             ++    K Q
Sbjct: 2622 QIKQYQQKSQ 2631



 Score =  142 bits (344), Expect = 7e-32
 Identities = 211/1184 (17%), Positives = 490/1184 (41%), Gaps = 73/1184 (6%)

Query: 409  KLEMVIQSLNKDLVDK-EYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIH 467
            +++ +I  +N  +++  +Y  +  D             ++L    Q   +  M+     +
Sbjct: 572  EIQQIISHINNQMIELIDYQATHPDVENDQEHGSVGSSNSLEGNKQDIAELRMQIEEYCN 631

Query: 468  VGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMI 527
                 E  NE  + Q  LK++  ++     ++ L+ +L+  +    Q+  +++  N+N  
Sbjct: 632  KNIMLERENEQLQEQFLLKEKETEKFIG-ELQILLNQLRIQD----QVQSDVETLNQNER 686

Query: 528  KVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGN-LQLHLV 586
             + S   L +  + +++    +V +S K      + L    Q   + +E   N LQ +L+
Sbjct: 687  NLVS---LSISNLGESLGAIKEVVNSYKMHENQIQLLEQQLQIAIQSQENLTNQLQNNLI 743

Query: 587  DYDSGRM-IESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYD--EVEDK 643
              +S +  I   +  ++  +++L +      S L+ +     + +  L+ + D    +DK
Sbjct: 744  SENSQKSEIIKQLDSQLQNLKSLLQQEQSINSDLQEENGRQRERIEQLRDQLDIFRQKDK 803

Query: 644  LADISQLQSDQVC--SEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLEN 701
             +  S+   D     S++ S + ++Q+      ++    +IE    + ++ Y  +K    
Sbjct: 804  SSQQSKYNDDNSSQYSQLFSKYQQQQVQFNEVVRERD--IIEQKIQEMQRNYKEVKSKYE 861

Query: 702  DKEDIMNKLQNYIQENMDLTDKLEKMSA--EKISELLAKINHEEQSKIQTQFGIDAKIQE 759
              +D   K+Q  I +      +L+K S   E++  L   IN  +   I  Q     +   
Sbjct: 862  KSKDERKKMQKMISDQQQAITQLKKYSQSDEQVENLNQIINDLKNKLINQQQ--QQQQNN 919

Query: 760  RDLYIENIES---ELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEY 816
            +D Y  N E    +L+  K R+  L+++ A +E +   L  +   L    +E  K  SE 
Sbjct: 920  KDQYSSNTEELNQDLTVIKKRMSELQQNQADLEQKNKKLYTEKKDLSKAFKEVSKLNSEL 979

Query: 817  TIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHY 876
                DE + + + L +    + KQ  E+   N EL K+N  +    +  +I L     H 
Sbjct: 980  QRSNDEKIRQNSELANQISELSKQNQELSKANAELAKQNSEVTRAFKEARI-LGSSDSHK 1038

Query: 877  NALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQI 936
            N     +    LA  E+ + Q Q+RDL+   + +  ++Q L++Q    ++++++E    I
Sbjct: 1039 N-----SEGKHLA-IEAAEQQKQIRDLQKQNQELLKQNQQLLMQ----MQEVQLENKDLI 1088

Query: 937  ESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQ 996
            +    DK  +N   ++  E ++QL  +L+E ++N E +   +++   ++ + +D++  K 
Sbjct: 1089 KQI--DKSQIN--IDQQRETISQLNFKLKEIQSNYEGIYSKLKQQELLSNQQLDEN-SKN 1143

Query: 997  QTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTK 1056
                     +Y  ++NK    L Q  +E + + Q   + Q     +   +  +      K
Sbjct: 1144 NMDYQKIINEYEEKLNKTQIKLNQVFDEKLQIEQNNLDTQKELSQLQQKFRLQQESLQQK 1203

Query: 1057 LENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISS 1116
             + +E+E +  + +L    Q  +  +  + E+D  IK L + +L    ++  +   I S 
Sbjct: 1204 QKEIEDEKRSFAGKLEKLDQQIQNQKNKLNEKDMTIKRL-QFELQSSQSLNDSLNEIQSK 1262

Query: 1117 TIEPMSDDANNVDXXXXXXXXXXXXLKVQEE-----EEFIQERSV---LQEQSAKLNTEL 1168
                  DD   +             ++++EE      ++++ + +    Q++   L  E+
Sbjct: 1263 QKRTAYDDRQMLKQYESEDLNEEQIIELKEEIRQQQNKYLESQKINEKKQKEIELLRREV 1322

Query: 1169 QECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAV 1228
            +E   +I QL   N  L        ++IN LK++ E+ N    + ++  +  +   SS  
Sbjct: 1323 EEFQNEIQQLTQRNQSLNSRLQAQNQEINLLKNEKEEYNLLKHDQINENSSNQDRNSSES 1382

Query: 1229 DQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVT 1288
            ++ G    EL +  +  +E D +K + +LR + S  +   ++ L       Q++      
Sbjct: 1383 NE-GTSDLELARMQIEGQERDLEKLQIDLRTKDSYIDEMNQENLMLKDKVNQQQQEIRYL 1441

Query: 1289 MEQVTSLQNKLQD---KEEHLRNLQE-KYADVINQIEILRSEIEDEKVAFXXXXXXXXXX 1344
             EQV+ L +++++   +++ L  +Q+  + +   Q++ +  E  +E              
Sbjct: 1442 QEQVSQLNSEIEENVQRQDELIEMQKVNFENEREQMQKVLEENLEELKRLRNERGQTSDQ 1501

Query: 1345 XXXXXXDLRTENQSYKQMQ---EQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAK 1401
                   ++   Q Y++ Q   E+ + + N    + +K              ++      
Sbjct: 1502 VHSASKQIQFWQQEYEKAQQECEKVLSDFNLLQREFQKIQAESDLKSAKLQKQIERQSRV 1561

Query: 1402 VLELTHQLE----LKDSEIYQKTHEYTITLTQRND--------EFENVRQQLVEYEKRIE 1449
            + +   QL+    +  S  +    E  +  +  ++        ++  ++++  ++ +  +
Sbjct: 1562 IFDQEQQLQQSERMNSSRRFSSKKEDQLNQSSLSNSPEREWQKKYNQLKEENEQFSRDYQ 1621

Query: 1450 DLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELN 1509
             L  E +  L  +R K+ E+    +    E + E   L E+ +  + +   +  QVAE+ 
Sbjct: 1622 QLINENQRILEEVR-KLEESCLQLKERNSELDEENSSLREDNSALMQQVQQIKSQVAEIQ 1680

Query: 1510 KALEEEVAKTNEMQTALENQEIEI---VTLNDEITNLQNMVRAS 1550
            +  E++  K +E +   +  + E+    T+N ++ +    V+ S
Sbjct: 1681 QQYEQQAEKESEYEMLYKGTQDELQVSKTINKQVQDKLRQVQQS 1724



 Score =  138 bits (334), Expect = 1e-30
 Identities = 233/1172 (19%), Positives = 488/1172 (41%), Gaps = 86/1172 (7%)

Query: 212  EDTKQQMTKMQENFI--AMEAE----WKDEKQRLLKDIESKDVRISSLEEANKLLEAARF 265
            E+T++    +Q+ FI  A   E     +   ++L +D++ K+  + S EE   +++    
Sbjct: 2067 EETERLQQDLQKQFIITARNEEKIIFLEQSMEQLKQDLQQKEEILESKEE---IIQLKIE 2123

Query: 266  EISLEHSKLAQELEQXXXXXXXX--XXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTE 323
            EI     KL Q  E+                L ++ I+   E+  E EEK    + +   
Sbjct: 2124 EIKQLEGKLLQHEEKIHQLQDDIWQKEENSQLLEEKIQQLEEKIQEYEEKIQNLVEDNIS 2183

Query: 324  LTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKM- 382
                 E L+     I +  ++L+  L   G   K ++   +K + L  + +     +++ 
Sbjct: 2184 QNISQEQLQIQQKIIDEYTQKLDASLEKAGELQKQITFKQQKIAILEKQLNEVEAENELL 2243

Query: 383  KSPWSQLSSETLNQDTDKKINKNEIAKLE---MVIQSLNKDLVDK---EYVISEKDTXXX 436
            K        E    D   K +K +I  L+    V +S +K+ +++   +    +K     
Sbjct: 2244 KQNQEVREQEFALIDEQIKSHKEQIQNLKNQLQVSESKSKEKLEQNSDQKRNQQKKIEEY 2303

Query: 437  XXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDV 496
                    +  L +Q Q E Q +     LI      + +NE     E+   +L   IKD+
Sbjct: 2304 EQKLESLNQQFLQSQNQYEDQINQCNQQLIQARNKEKQLNETISQNEKTIDDLRINIKDL 2363

Query: 497  N--VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTI--DNFSKVSD 552
            N  V + I+K+    EQ+ Q  ++ ++  +  +  K   + +   +++ +   N +   +
Sbjct: 2364 NNLVYEQIDKINELTEQLNQEREQFNSDLQKEVLAKQEQESEFNSIKQQLHEQNDTLKKE 2423

Query: 553  SNKEIVRLTEELHHLSQKVAELE-----EEKGNLQLHLVDYDSGRMIESDVYKKMIEMEN 607
              +EI  L +++ HL ++   LE     + +  + +      S + I +++ ++  ++  
Sbjct: 2424 KEREIQILKDQIEHLEKEKNNLELNIEKQREEEMSMLRAQIASHKDIINELRQERTKISQ 2483

Query: 608  LAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQ 667
              +++ + I  LE Q   +  +   LQ+  +++++K+ DI+Q + +++   +  V LE++
Sbjct: 2484 SDQSKAEEIQKLEQQLNQIKYDKDELQENVNQLQNKI-DINQNEKNEISKMLNEVTLEKE 2542

Query: 668  IDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKM 727
                    KE  L  + L  +  ++    + LE  + +I N  QN    +    +++  +
Sbjct: 2543 RKEKDFKNKEETLN-QQLNEENRKVLQLQEKLEKHQTEIANLRQNLADLSSSSQEEINII 2601

Query: 728  SAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAV 787
              +  S+++A  N+ +  + Q +        + D  I   E ++    ++   L   +  
Sbjct: 2602 REQLNSQVIASNNNIQMLQDQIKQYQQKSQSDADSQILQREQKIVDLVNQNTELNNQLHE 2661

Query: 788  MEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDR-VVEKQ----LL 842
               +   L  K  Q  + L+E          ++ E  N+L +   H++ ++EK+    L 
Sbjct: 2662 ANTKISQLNAKNQQEKARLEESITLKESQLEEQKEQQNQLKLSFQHEKSILEKEKDQLLQ 2721

Query: 843  EIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRD 902
            +I  +N E+    Q   E N+      S+ Q+  +    + ++T+    ES K Q+ L+ 
Sbjct: 2722 QISQQNDEISSLTQKETEFNEQK----SEYQEKISKFKAQLDQTNAKLEESLKEQSNLKQ 2777

Query: 903  LESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRD--KKVLNEKYEK-NIEY-VT 958
              S     +++  T I   + E+E L      QI     D   ++  EK+EK N++  +T
Sbjct: 2778 QISLQNENSNQQNTKIEDLQTEVEQLN-NLIKQINQKYLDLQHEIQKEKFEKANLQKEIT 2836

Query: 959  QLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALL 1018
              +   Q  +   EN     E+  K+   +   H Q+       Y +++  ++      L
Sbjct: 2837 HCKEDYQIVQQKYENFQAQHEDQLKL---IKSTHAQESAHLKKQYQQEFQQKLIDTQKDL 2893

Query: 1019 KQKDEEIIALNQKINNAQVSYMS-MVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQH 1077
            + K E  + + QK  + Q+S +   ++ Y+  L +    +   ++++Q + + +   KQ 
Sbjct: 2894 QSKHE--VEIKQK--DEQISKLQDELTQYKLNLEEQKQLITQNDKQVQELKQNIEQEKQL 2949

Query: 1078 NEELQILVREQD-------DQIKELKETK----LTFEMNIPKTEGMIISSTIEPMSDDAN 1126
            N++LQ  + +Q+       D+I+ LK+++     T  +N   T  +   + I P      
Sbjct: 2950 NQDLQNQLLQQEKYLHKKIDEIQVLKKSQELIQSTHSINDHNTATLRSDNDISPTMSLGR 3009

Query: 1127 NVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKI-----IQLETL 1181
                           L+ ++E E +Q  S+L ++  K N   +E   K+     +Q    
Sbjct: 3010 AKKVESYREDQDKIILQYKKEIENLQ--SLLNQEKEKCNLLNEEIKLKVQAEAPMQRREN 3067

Query: 1182 NTELTG---HDVVNQEQINQLKSKLEQLNTENDNL---LSTVAELRSSISSAVDQRGFEI 1235
            N E +    H  +   Q  +L  + ++L  END L    S  A+   ++       G   
Sbjct: 3068 NQETSAEKDHYQILISQNQRLIQENQRLKEENDKLKEEYSYYADNSVTLQQTNPVSGQNT 3127

Query: 1236 AELWKQHLAQREADFQKTEHELRVQL--SAFESKYEQL-------LDSVQSSTQEETNKI 1286
            A       AQ +   Q T+ EL+VQ+       + EQ+       L+ +Q   Q+E    
Sbjct: 3128 ASQSASKPAQ-DLQTQNTDIELQVQILQEQISKQNEQIVKNEQNILEFIQQKEQQEQQYH 3186

Query: 1287 VTMEQVTSLQNKLQDKEEHLRNLQEKYADVIN 1318
              + +  +++NKL +KE  +R LQ+ YAD ++
Sbjct: 3187 NLLIEFNNVKNKLIEKENEIRFLQQ-YADKLS 3217



 Score =  124 bits (300), Expect = 2e-26
 Identities = 253/1246 (20%), Positives = 536/1246 (43%), Gaps = 141/1246 (11%)

Query: 144  VTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXX 203
            +  L+N I+EKD  +  LQ ++    + I  L+E + +++Q    KN             
Sbjct: 1880 IEDLNNRIEEKDRDIQDLQNRIGDQLSQIQRLKEDLTQEEQ----KNVQIQSIQIEKDQK 1935

Query: 204  XXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAA 263
                    E    ++T +Q     +  +       L +  ++K   ++  +E  K  +  
Sbjct: 1936 IQVLEEQAESLTDEITNLQGQIDILNRQLNSSYNTLSEIQKNKQTFVNQDKELEKFQQIQ 1995

Query: 264  RFE------ISLEHSKLAQELEQXXX----XXXXXXXXXXXLAKQSIEPSCEEKTEIEEK 313
              +      + +E+ KL QEL Q                  L++Q+     + K  +EEK
Sbjct: 1996 ADQQKQIDSLLIENEKLQQELSQQKSDFEESQKMLNQQTVQLSEQAQHKQEQLKNYLEEK 2055

Query: 314  GSLEI--ANMTELTKKIELLEHLNCQIRQTNKE----LENKLATM--GTESKAVSSPSKK 365
             ++ +  +N+ E T++++        I   N+E    LE  +  +    + K     SK+
Sbjct: 2056 NTILVDNSNLKEETERLQQDLQKQFIITARNEEKIIFLEQSMEQLKQDLQQKEEILESKE 2115

Query: 366  GSPLISRKSGRNTASKM---KSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLV 422
                +  +  +    K+   +    QL  +   ++ + ++ + +I +LE  IQ   + + 
Sbjct: 2116 EIIQLKIEEIKQLEGKLLQHEEKIHQLQDDIWQKEENSQLLEEKIQQLEEKIQEYEEKIQ 2175

Query: 423  D--KEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLI---HVGTNTEDVNE 477
            +  ++ +                 + T      LE    ++         +    + +NE
Sbjct: 2176 NLVEDNISQNISQEQLQIQQKIIDEYTQKLDASLEKAGELQKQITFKQQKIAILEKQLNE 2235

Query: 478  IAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAA-NKNMIKVKSNHKLK 536
            +    E LKQ  N E+++     + E++KS +EQI  L +++  + +K+  K++ N   K
Sbjct: 2236 VEAENELLKQ--NQEVREQEFALIDEQIKSHKEQIQNLKNQLQVSESKSKEKLEQNSDQK 2293

Query: 537  LKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIES 596
              Q +K  +   K+   N++ ++        SQ   E +  + N QL +   +  + +  
Sbjct: 2294 RNQQKKIEEYEQKLESLNQQFLQ--------SQNQYEDQINQCNQQL-IQARNKEKQLNE 2344

Query: 597  DVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQ--LQSDQ 654
             + +    +++L    +K ++ L  ++ D + EL   +Q   E E   +D+ +  L   +
Sbjct: 2345 TISQNEKTIDDL-RINIKDLNNLVYEQIDKINEL--TEQLNQEREQFNSDLQKEVLAKQE 2401

Query: 655  VCSEIKSV--HLEEQIDALSASK-KELALV---IENLKLDKEQLYGTIKDLENDKEDIMN 708
              SE  S+   L EQ D L   K +E+ ++   IE+L+ +K  L     ++E  +E+ M+
Sbjct: 2402 QESEFNSIKQQLHEQNDTLKKEKEREIQILKDQIEHLEKEKNNLE---LNIEKQREEEMS 2458

Query: 709  KLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIE 768
             L+  I  + D+ ++L +   E+      KI+  +QSK +       +IQ+ +  +  I+
Sbjct: 2459 MLRAQIASHKDIINELRQ---ER-----TKISQSDQSKAE-------EIQKLEQQLNQIK 2503

Query: 769  SELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLA 828
             +  + +  + +L+  I + ++ +  + +    L     EK++   ++  +E+ L  +L 
Sbjct: 2504 YDKDELQENVNQLQNKIDINQNEKNEISK---MLNEVTLEKERKEKDFKNKEETLNQQL- 2559

Query: 829  VLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDL 888
                      +++L+++   ++L+K    +    QNL    S  Q+  N + E+ N   +
Sbjct: 2560 ------NEENRKVLQLQ---EKLEKHQTEIANLRQNLADLSSSSQEEINIIREQLNSQVI 2610

Query: 889  AESESTK-YQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLN 947
            A + + +  Q Q++  +   ++   +  + I+Q++++I DL +  NT++          N
Sbjct: 2611 ASNNNIQMLQDQIKQYQ---QKSQSDADSQILQREQKIVDL-VNQNTELN---------N 2657

Query: 948  EKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQY 1007
            + +E N + ++QL A+ Q+ K  +E      E +     +L ++  Q+ Q +     E+ 
Sbjct: 2658 QLHEANTK-ISQLNAKNQQEKARLE------ESITLKESQLEEQKEQQNQLKLSFQHEKS 2710

Query: 1008 INEINKLNAL--LKQKDEEIIALNQK---INNAQVSYMSMVSDYESKLAQFTTKLENMEE 1062
            I E  K   L  + Q+++EI +L QK    N  +  Y   +S ++++L Q   KLE   +
Sbjct: 2711 ILEKEKDQLLQQISQQNDEISSLTQKETEFNEQKSEYQEKISKFKAQLDQTNAKLEESLK 2770

Query: 1063 EM----QRVSKQLLDSKQHN---EELQILVREQDDQIKELKETKLTFEMNIPKT--EGMI 1113
            E     Q++S Q  +S Q N   E+LQ  V + ++ IK++ +  L  +  I K   E   
Sbjct: 2771 EQSNLKQQISLQNENSNQQNTKIEDLQTEVEQLNNLIKQINQKYLDLQHEIQKEKFEKAN 2830

Query: 1114 ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYT 1173
            +   I    +D   V              + Q E++    +S   ++SA L  + Q+ + 
Sbjct: 2831 LQKEITHCKEDYQIVQ-------QKYENFQAQHEDQLKLIKSTHAQESAHLKKQYQQEFQ 2883

Query: 1174 KIIQLETLNTELTGHDV-VNQ--EQINQLKSKLEQ--LNTENDNLLSTVAELR-SSISSA 1227
            + + ++T     + H+V + Q  EQI++L+ +L Q  LN E    L T  + +   +   
Sbjct: 2884 QKL-IDTQKDLQSKHEVEIKQKDEQISKLQDELTQYKLNLEEQKQLITQNDKQVQELKQN 2942

Query: 1228 VDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIV 1287
            ++Q   ++ +  +  L Q+E    K   E++V       K ++L+ S  S     T  + 
Sbjct: 2943 IEQEK-QLNQDLQNQLLQQEKYLHKKIDEIQVL-----KKSQELIQSTHSINDHNTATLR 2996

Query: 1288 TMEQVTSLQNKLQDKE-EHLRNLQEK-YADVINQIEILRSEIEDEK 1331
            +   ++   +  + K+ E  R  Q+K       +IE L+S +  EK
Sbjct: 2997 SDNDISPTMSLGRAKKVESYREDQDKIILQYKKEIENLQSLLNQEK 3042



 Score =  120 bits (289), Expect = 3e-25
 Identities = 201/1083 (18%), Positives = 467/1083 (43%), Gaps = 98/1083 (9%)

Query: 504  KLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEE 563
            K+   +E IT   +   +  +  +        KL Q  + + + +K+     E+  L  +
Sbjct: 322  KILKDKEAITMQTEYQMSQKEEEVNYLKEQIQKLMQESRNVLHENKILSDENEV--LQTK 379

Query: 564  LHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAIS-LLESQ 622
            +  L  K+AE+E++  + +  L    S    + D  K +    N     +   +  ++  
Sbjct: 380  IKTLKAKLAEVEKKSADRKASLKQVYSILQQKDDQIKMLQANNNNNNNNMNNFNNAIQQN 439

Query: 623  KFDLVQELH--ILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELAL 680
               L    +  I+ Q  D+   +LA++ +   +Q     ++V+ +  I A       L  
Sbjct: 440  SASLAAASNSIIINQIKDDFARQLAEVEKSFLNQFHQIERAVNQKNDIIA------NLED 493

Query: 681  VIENLKLDKEQLYGTIK-DLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKI 739
             I+NL L K  +    K DL +  E  ++   +   +N +  ++ + + A+K+ +L AK 
Sbjct: 494  QIKNLNLSKRNITSNNKIDLSSPIEFTLSNNTSKRNQNANTVNQEQLIRAKKM-DLEAK- 551

Query: 740  NHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKA 799
               E      Q   +   Q+R    + I+  +S   +++  L +  A   D     E  +
Sbjct: 552  --RENLVDIIQNNPNLPTQKR----QEIQQIISHINNQMIELIDYQATHPDVENDQEHGS 605

Query: 800  DQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILL 859
                + L+  ++  +E  +Q +E  N+  +L   +  +++Q L  E E ++   + QILL
Sbjct: 606  VGSSNSLEGNKQDIAELRMQIEEYCNKNIMLERENEQLQEQFLLKEKETEKFIGELQILL 665

Query: 860  EE---NQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQT 916
             +      +Q  +  + Q+   LV   + ++L ES        ++++ ++ K   HE+Q 
Sbjct: 666  NQLRIQDQVQSDVETLNQNERNLV-SLSISNLGESLGA-----IKEVVNSYK--MHENQI 717

Query: 917  LIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNI---EN 973
             +++++ +I    I+    + + +++  +++E  +K+ E + QL++QLQ  K+ +   ++
Sbjct: 718  QLLEQQLQI---AIQSQENLTNQLQN-NLISENSQKS-EIIKQLDSQLQNLKSLLQQEQS 772

Query: 974  LNMNVEELNKMNLELIDK-----HVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIAL 1028
            +N +++E N    E I++      + +Q+ +S   ++   +  ++ + L  +  ++ +  
Sbjct: 773  INSDLQEENGRQRERIEQLRDQLDIFRQKDKSSQQSKYNDDNSSQYSQLFSKYQQQQVQF 832

Query: 1029 NQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQ 1088
            N+ +    +     + + +    +  +K E  ++E +++ K + D +Q   +L+    + 
Sbjct: 833  NEVVRERDI-IEQKIQEMQRNYKEVKSKYEKSKDERKKMQKMISDQQQAITQLK-KYSQS 890

Query: 1089 DDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKV--QE 1146
            D+Q++ L +        I   +  +I+   +      NN D            L V  + 
Sbjct: 891  DEQVENLNQI-------INDLKNKLIN---QQQQQQQNNKDQYSSNTEELNQDLTVIKKR 940

Query: 1147 EEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQL 1206
              E  Q ++ L++++ KL TE ++      ++  LN+EL   +     Q ++L +++ +L
Sbjct: 941  MSELQQNQADLEQKNKKLYTEKKDLSKAFKEVSKLNSELQRSNDEKIRQNSELANQISEL 1000

Query: 1207 NTENDNLLSTVAELRSSISSAVDQRGFEIAELW----------KQHLAQREADFQKTEHE 1256
            + +N  L    AEL    S     R F+ A +            +HLA   A+ QK   +
Sbjct: 1001 SKQNQELSKANAELAKQNSEVT--RAFKEARILGSSDSHKNSEGKHLAIEAAEQQKQIRD 1058

Query: 1257 LRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADV 1316
            L+ Q      + +QLL  +Q    E  + I   +Q+   Q  +  + E +  L  K  ++
Sbjct: 1059 LQKQNQELLKQNQQLLMQMQEVQLENKDLI---KQIDKSQINIDQQRETISQLNFKLKEI 1115

Query: 1317 INQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNIN---EE 1373
             +  E + S+++ +++                  D +     Y++   ++ + +N   +E
Sbjct: 1116 QSNYEGIYSKLKQQEL----LSNQQLDENSKNNMDYQKIINEYEEKLNKTQIKLNQVFDE 1171

Query: 1374 NAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDE 1433
              Q+++++             ++  + K       L+ K  EI  +   +   L + + +
Sbjct: 1172 KLQIEQNN-------LDTQKELSQLQQKFRLQQESLQQKQKEIEDEKRSFAGKLEKLDQQ 1224

Query: 1434 FENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNV 1493
             +N + +L E +  I+ L +E +S  +     ++++ N  ++ QK +  +  +++++   
Sbjct: 1225 IQNQKNKLNEKDMTIKRLQFELQSSQS-----LNDSLNEIQSKQKRTAYDDRQMLKQY-- 1277

Query: 1494 KITESVSLN-KQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSS 1552
               ES  LN +Q+ EL + + ++  K  E Q   E ++ EI  L  E+   QN ++  + 
Sbjct: 1278 ---ESEDLNEEQIIELKEEIRQQQNKYLESQKINEKKQKEIELLRREVEEFQNEIQQLTQ 1334

Query: 1553 KIQ 1555
            + Q
Sbjct: 1335 RNQ 1337



 Score = 94.3 bits (224), Expect = 2e-17
 Identities = 241/1215 (19%), Positives = 489/1215 (40%), Gaps = 101/1215 (8%)

Query: 62   ENAALVSKRIKEHRKATAELLG-RPFVPGISESLANTLKQKEILMEKIKQYKELSKRSST 120
            E  +++  +I  H+    EL   R  +    +S A  +++ E  + +IK  K+   + + 
Sbjct: 2455 EEMSMLRAQIASHKDIINELRQERTKISQSDQSKAEEIQKLEQQLNQIKYDKD-ELQENV 2513

Query: 121  TIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKD--NALSVLQVKMKIMETTILDLQEK 178
              ++                L +VT L    KEKD  N    L  ++      +L LQEK
Sbjct: 2514 NQLQNKIDINQNEKNEISKMLNEVT-LEKERKEKDFKNKEETLNQQLNEENRKVLQLQEK 2572

Query: 179  INEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQR 238
            + EK Q   A  +                    E    Q+     N   ++ + K  +Q+
Sbjct: 2573 L-EKHQTEIANLRQNLADLSSSSQEEINIIR--EQLNSQVIASNNNIQMLQDQIKQYQQK 2629

Query: 239  LLKDIES----KDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXX 294
               D +S    ++ +I  L   N  L     E + + S+L  + +Q              
Sbjct: 2630 SQSDADSQILQREQKIVDLVNQNTELNNQLHEANTKISQLNAKNQQEKARLEESITLKES 2689

Query: 295  LAKQSIEPSCEEKTEIE-EKGSLEIANMTELTKKIELLEHLNCQIRQ-TNKELENKLATM 352
              ++  E   + K   + EK  LE     E  + ++ +   N +I   T KE E      
Sbjct: 2690 QLEEQKEQQNQLKLSFQHEKSILE----KEKDQLLQQISQQNDEISSLTQKETEFNEQKS 2745

Query: 353  GTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEM 412
              + K     ++        +      S +K   S  +  +  Q+T  +  + E+ +L  
Sbjct: 2746 EYQEKISKFKAQLDQTNAKLEESLKEQSNLKQQISLQNENSNQQNTKIEDLQTEVEQLNN 2805

Query: 413  VIQSLNKDLVDKEYVISEK--DTXXXXXXXXXXGKDTLIAQLQLEH--QQHMEGPSLIHV 468
            +I+ +N+  +D ++ I ++  +            +D  I Q + E+   QH +   LI  
Sbjct: 2806 LIKQINQKYLDLQHEIQKEKFEKANLQKEITHCKEDYQIVQQKYENFQAQHEDQLKLIKS 2865

Query: 469  GTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIK 528
                E  +   + Q++ +Q+L D  KD+  K  +E +K  +EQI++L DE+     N+ +
Sbjct: 2866 THAQESAHLKKQYQQEFQQKLIDTQKDLQSKHEVE-IKQKDEQISKLQDELTQYKLNLEE 2924

Query: 529  VKSNHKLKLKQMQKTIDNFSKVSDSNKEIV-RLTEELHHLSQKVAELEEEKGNLQL---- 583
             K       KQ+Q+   N  +    N+++  +L ++  +L +K+ E++  K + +L    
Sbjct: 2925 QKQLITQNDKQVQELKQNIEQEKQLNQDLQNQLLQQEKYLHKKIDEIQVLKKSQELIQST 2984

Query: 584  HLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQ---ELHILQQKYDEV 640
            H ++  +   + SD    +    +L   + K  S  E Q   ++Q   E+  LQ   ++ 
Sbjct: 2985 HSINDHNTATLRSD--NDISPTMSLGRAK-KVESYREDQDKIILQYKKEIENLQSLLNQE 3041

Query: 641  EDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLE 700
            ++K   +++    +V +E      E   +  +       L+ +N +L +E     +K+ E
Sbjct: 3042 KEKCNLLNEEIKLKVQAEAPMQRRENNQETSAEKDHYQILISQNQRLIQENQ--RLKE-E 3098

Query: 701  NDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQER 760
            NDK   + +  +Y  +N     +   +S +  +   A    ++     T   +  +I + 
Sbjct: 3099 NDK---LKEEYSYYADNSVTLQQTNPVSGQNTASQSASKPAQDLQTQNTDIELQVQILQE 3155

Query: 761  DLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQ------KAYS 814
             +  +N   ++ K +  I    +     E + ++L  + + + + L EK+      + Y+
Sbjct: 3156 QISKQN--EQIVKNEQNILEFIQQKEQQEQQYHNLLIEFNNVKNKLIEKENEIRFLQQYA 3213

Query: 815  EYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLE-------ENQ-NLQ 866
            +    + E         +++R  ++Q +  + +N+ ++ +N   LE       ENQ    
Sbjct: 3214 DKLSSQQEYTVYSTEGNNNNRQQQQQHIPNQLQNQNVKIRNISFLEQEGSQFEENQFEDY 3273

Query: 867  ISLSDMQQ---HYNA-LVEKANRTDLAESESTKYQ----TQLRDLESNLKRITHEHQTLI 918
            I   D  +   H +A +V   N  + + +    +     +Q  + +++  R ++  Q+ I
Sbjct: 3274 IHQEDAHRGSVHTSAEIVVNVNDINASNTLGRGFAQASGSQQNNQQNSNIRNSNSMQSNI 3333

Query: 919  VQ------KKKEIEDLEIEFNTQIES--AIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNN 970
            +Q        ++ E+  ++ N    S  ++ +   + +K ++ +E +   +    E  N+
Sbjct: 3334 LQGLNFNANNQQDEETNVQNNQPYNSNLSVEEGFAVLQKIDQAMEKIVW-DMDCNEELND 3392

Query: 971  IENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQ 1030
            IE            NL L+ + + K  +      E+    I KL A L++KDE+I  LNQ
Sbjct: 3393 IEKNQSFCSNSISQNLRLLMEKIHKSTSNRTLDNER----IEKLQAKLEEKDEQIAFLNQ 3448

Query: 1031 KINNAQ----VSYMSMVSDYESKLAQFTTKLEN----MEEEMQRVSKQLLDSKQHNEELQ 1082
            K+   Q    +   S+V D   K    +    N     E+++Q+ S      K+  + LQ
Sbjct: 3449 KLQELQNVQKLLKRSIVQDINEKDPDVSRIDINPHSPKEQQIQQPSSPSASPKKSAKNLQ 3508

Query: 1083 ILVREQDDQIKELK--ETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXX 1140
             L     D+++ELK     LT+E +  + E   +   I    ++   V            
Sbjct: 3509 QL----KDEVRELKYQVQDLTYERDQLELENERLQMEIRDFENEQERVQSQISLLKQEIK 3564

Query: 1141 XLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLK 1200
             L+ Q     I E S + +Q+  L T L + +  IIQL++  TE    +    + +N + 
Sbjct: 3565 QLQSQN----IDEGSRIIKQT--LKTILPK-FLNIIQLKS-KTESQNQEAT--QYLNVML 3614

Query: 1201 SKLEQLNTENDNLLS 1215
            + LE    E DN++S
Sbjct: 3615 NLLEFSEPEKDNIIS 3629



 Score = 91.1 bits (216), Expect = 2e-16
 Identities = 269/1396 (19%), Positives = 554/1396 (39%), Gaps = 161/1396 (11%)

Query: 65   ALVSKRIKEHRKATAELLGRPFVPGIS--ESLANTLKQKEILMEKIKQYKELSKRSSTTI 122
            AL+ ++IK H++    L  +  V      E L     QK    +KI++Y++  +  +   
Sbjct: 2255 ALIDEQIKSHKEQIQNLKNQLQVSESKSKEKLEQNSDQKRNQQKKIEEYEQKLESLNQQF 2314

Query: 123  VRXXXXXXXXXXXXXXXQL---GDVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKI 179
            ++                +        L+ TI + +  +  L++ +K +   + +  +KI
Sbjct: 2315 LQSQNQYEDQINQCNQQLIQARNKEKQLNETISQNEKTIDDLRINIKDLNNLVYEQIDKI 2374

Query: 180  NEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAE-----WKD 234
            NE  + +  + +                       KQQ+ + Q + +  E E      KD
Sbjct: 2375 NELTEQLNQEREQFNSDLQKEVLAKQEQESEFNSIKQQLHE-QNDTLKKEKEREIQILKD 2433

Query: 235  EKQRLLKDIESKDVRISSLEEANKLLEAARF--------EISLEHSKLAQELEQXXXXXX 286
            + + L K+  + ++ I    E    +  A+         E+  E +K++Q  +       
Sbjct: 2434 QIEHLEKEKNNLELNIEKQREEEMSMLRAQIASHKDIINELRQERTKISQSDQSKAEEIQ 2493

Query: 287  XXXXXXXXLA--KQSIEPSCEE---KTEIEEKGSLEIANM-TELTKKIELLEH------- 333
                    +   K  ++ +  +   K +I +    EI+ M  E+T + E  E        
Sbjct: 2494 KLEQQLNQIKYDKDELQENVNQLQNKIDINQNEKNEISKMLNEVTLEKERKEKDFKNKEE 2553

Query: 334  -LNCQIRQTNK---ELENKLATMGTESKAV-------SSPSKKGSPLISRK------SGR 376
             LN Q+ + N+   +L+ KL    TE   +       SS S++   +I  +      +  
Sbjct: 2554 TLNQQLNEENRKVLQLQEKLEKHQTEIANLRQNLADLSSSSQEEINIIREQLNSQVIASN 2613

Query: 377  NTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQS--LNKDLVDKEYVISEKDTX 434
            N    ++    Q   ++   D D +I + E   +++V Q+  LN  L +    IS+ +  
Sbjct: 2614 NNIQMLQDQIKQYQQKS-QSDADSQILQREQKIVDLVNQNTELNNQLHEANTKISQLNAK 2672

Query: 435  XXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQEL---ND 491
                        TL  + QLE Q+  +    +       + + + K ++QL Q++   ND
Sbjct: 2673 NQQEKARLEESITL-KESQLEEQKEQQNQLKLSF---QHEKSILEKEKDQLLQQISQQND 2728

Query: 492  EIKDVNVKD--LIEKLKSAEEQITQLNDEIDAANKNM---IKVKSNHKLKLK-QMQKTID 545
            EI  +  K+    E+    +E+I++   ++D  N  +   +K +SN K ++  Q + +  
Sbjct: 2729 EISSLTQKETEFNEQKSEYQEKISKFKAQLDQTNAKLEESLKEQSNLKQQISLQNENSNQ 2788

Query: 546  NFSKVSDSNKEIVRLTEELHHLSQKVAELEEE-------KGNLQLHLVDYDSGRMIESDV 598
              +K+ D   E+ +L   +  ++QK  +L+ E       K NLQ  +        I   V
Sbjct: 2789 QNTKIEDLQTEVEQLNNLIKQINQKYLDLQHEIQKEKFEKANLQKEITHCKEDYQI---V 2845

Query: 599  YKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQ-LQSDQVCS 657
             +K    +   E +LK I    +Q     +  H+ +Q   E + KL D  + LQS     
Sbjct: 2846 QQKYENFQAQHEDQLKLIKSTHAQ-----ESAHLKKQYQQEFQQKLIDTQKDLQSKH--- 2897

Query: 658  EIKSVHLEEQIDALSASKKELALVIENLKL----DKEQLYGTIKDLENDKEDIMNKLQNY 713
            E++    +EQI  L     +  L +E  K     + +Q+    +++E +K+ +   LQN 
Sbjct: 2898 EVEIKQKDEQISKLQDELTQYKLNLEEQKQLITQNDKQVQELKQNIEQEKQ-LNQDLQNQ 2956

Query: 714  I-QENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLY--IENIESE 770
            + Q+   L  K++++   K S+ L +  H            D  I         + +ES 
Sbjct: 2957 LLQQEKYLHKKIDEIQVLKKSQELIQSTHSINDHNTATLRSDNDISPTMSLGRAKKVESY 3016

Query: 771  LSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVL 830
                   I + ++ I  ++      + K + L   +  K K  +E  +Q  E     +  
Sbjct: 3017 REDQDKIILQYKKEIENLQSLLNQEKEKCNLLNEEI--KLKVQAEAPMQRRENNQETSAE 3074

Query: 831  MDHDRVVEKQLLEIEHENKELQKKNQILLEE-----NQNLQISLSDMQQHYNALVEKANR 885
             DH +++  Q   +  EN+ L+++N  L EE     + ++ +  ++     N   + A++
Sbjct: 3075 KDHYQILISQNQRLIQENQRLKEENDKLKEEYSYYADNSVTLQQTNPVSGQNTASQSASK 3134

Query: 886  T--DLAESESTKYQTQLRDLESNLKR----ITHEHQTLI--VQKKKEIE----DLEIEFN 933
               DL ++++T  + Q++ L+  + +    I    Q ++  +Q+K++ E    +L IEFN
Sbjct: 3135 PAQDL-QTQNTDIELQVQILQEQISKQNEQIVKNEQNILEFIQQKEQQEQQYHNLLIEFN 3193

Query: 934  T------QIESAIRDKKVLNEKYEKNIEYVT--------QLEAQLQEYKNNIENLNMNVE 979
                   + E+ IR  +   +K     EY            + Q Q   N ++N N+ + 
Sbjct: 3194 NVKNKLIEKENEIRFLQQYADKLSSQQEYTVYSTEGNNNNRQQQQQHIPNQLQNQNVKIR 3253

Query: 980  ELNKMNLE-------LIDKHVQKQQTQ--SPDYTEQYINEINKLNALLKQKDEEIIALNQ 1030
             ++ +  E         + ++ ++     S   + + +  +N +NA          A   
Sbjct: 3254 NISFLEQEGSQFEENQFEDYIHQEDAHRGSVHTSAEIVVNVNDINASNTLGRGFAQASGS 3313

Query: 1031 KINNAQVSYMSMVSDYESKLAQ-FTTKLENMEEEMQRV-SKQLLDSKQHNEELQILVREQ 1088
            + NN Q S +   +  +S + Q       N ++E   V + Q  +S    EE   ++++ 
Sbjct: 3314 QQNNQQNSNIRNSNSMQSNILQGLNFNANNQQDEETNVQNNQPYNSNLSVEEGFAVLQKI 3373

Query: 1089 DDQIKELK-ETKLTFEMN-IPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXL-KVQ 1145
            D  ++++  +     E+N I K +    +S  + +      +             + K+Q
Sbjct: 3374 DQAMEKIVWDMDCNEELNDIEKNQSFCSNSISQNLRLLMEKIHKSTSNRTLDNERIEKLQ 3433

Query: 1146 EE-EEFIQERSVLQEQSAKLNTELQECYTKIIQ-LETLNTELTGHDV----VNQEQINQL 1199
             + EE  ++ + L ++  +L    +     I+Q +   + +++  D+      ++QI Q 
Sbjct: 3434 AKLEEKDEQIAFLNQKLQELQNVQKLLKRSIVQDINEKDPDVSRIDINPHSPKEQQIQQP 3493

Query: 1200 KSKLEQLNTENDNLLST---VAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHE 1256
             S          NL      V EL+  +     +R  +  EL  + L     DF+  +  
Sbjct: 3494 SSPSASPKKSAKNLQQLKDEVRELKYQVQDLTYER--DQLELENERLQMEIRDFENEQER 3551

Query: 1257 LRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQN-----KLQDKEEHLRNLQE 1311
            ++ Q+S  + + +QL    QS   +E ++I+     T L       +L+ K E       
Sbjct: 3552 VQSQISLLKQEIKQL----QSQNIDEGSRIIKQTLKTILPKFLNIIQLKSKTESQNQEAT 3607

Query: 1312 KYADV-INQIEILRSE 1326
            +Y +V +N +E    E
Sbjct: 3608 QYLNVMLNLLEFSEPE 3623



 Score = 77.4 bits (182), Expect = 3e-12
 Identities = 157/807 (19%), Positives = 332/807 (41%), Gaps = 77/807 (9%)

Query: 768  ESELSKYK-SRICRLEESIAVMEDRRYSLERKA-----DQLGSYLQEKQKAYSEYTIQED 821
            E E  KYK ++I + +E+I +  + + S + +      +Q+   +QE +    E  I  D
Sbjct: 312  EKEYYKYKYNKILKDKEAITMQTEYQMSQKEEEVNYLKEQIQKLMQESRNVLHENKILSD 371

Query: 822  E---LVNRLAVLMDHDRVVEKQLLEIEHENKEL-----QKKNQILL-----EENQNLQIS 868
            E   L  ++  L      VEK+  + +   K++     QK +QI +       N N   +
Sbjct: 372  ENEVLQTKIKTLKAKLAEVEKKSADRKASLKQVYSILQQKDDQIKMLQANNNNNNNNMNN 431

Query: 869  LSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDL 928
             ++  Q  +A +  A+ + +       +  QL ++E +     H+ +  + QK   I +L
Sbjct: 432  FNNAIQQNSASLAAASNSIIINQIKDDFARQLAEVEKSFLNQFHQIERAVNQKNDIIANL 491

Query: 929  EIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEEL---NKMN 985
            E     QI++    K+ +    + ++    +        K N     +N E+L    KM+
Sbjct: 492  E----DQIKNLNLSKRNITSNNKIDLSSPIEFTLSNNTSKRNQNANTVNQEQLIRAKKMD 547

Query: 986  LELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSD 1045
            LE   +++      +P+   Q   EI ++ + +  +  E+I       + Q ++  + +D
Sbjct: 548  LEAKRENLVDIIQNNPNLPTQKRQEIQQIISHINNQMIELI-------DYQATHPDVEND 600

Query: 1046 YESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQ--IKELKETKLTFE 1103
             E      +  LE  ++++  +  Q+ +    N  L+    +  +Q  +KE +  K   E
Sbjct: 601  QEHGSVGSSNSLEGNKQDIAELRMQIEEYCNKNIMLERENEQLQEQFLLKEKETEKFIGE 660

Query: 1104 MNIPKTEGMI---ISSTIEPMSDDANN-VDXXXXXXXXXXXXLKVQEEEEFIQERSV-LQ 1158
            + I   +  I   + S +E ++ +  N V             +K       + E  + L 
Sbjct: 661  LQILLNQLRIQDQVQSDVETLNQNERNLVSLSISNLGESLGAIKEVVNSYKMHENQIQLL 720

Query: 1159 EQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQ--EQINQLKSKLEQLNTENDNLLST 1216
            EQ  ++  + QE  T  +Q   ++      +++ Q   Q+  LKS L+Q  + N +L   
Sbjct: 721  EQQLQIAIQSQENLTNQLQNNLISENSQKSEIIKQLDSQLQNLKSLLQQEQSINSDLQEE 780

Query: 1217 VAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQ 1276
                R  I    DQ      ++++Q    + +   K   +   Q S   SKY+Q      
Sbjct: 781  NGRQRERIEQLRDQ-----LDIFRQ--KDKSSQQSKYNDDNSSQYSQLFSKYQQ------ 827

Query: 1277 SSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFX- 1335
               Q + N++V    +  ++ K+Q+ + + + ++ KY    ++ + ++  I D++ A   
Sbjct: 828  --QQVQFNEVVRERDI--IEQKIQEMQRNYKEVKSKYEKSKDERKKMQKMISDQQQAITQ 883

Query: 1336 ----XXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXX 1391
                               DL+ +  + +Q Q+Q+  +    N + + +           
Sbjct: 884  LKKYSQSDEQVENLNQIINDLKNKLINQQQQQQQNNKDQYSSNTE-ELNQDLTVIKKRMS 942

Query: 1392 XXRVNDAEAKVLELTHQLELKD-SEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIED 1450
              + N A+ +        E KD S+ +++  +    L + ND  E +RQ   E   +I +
Sbjct: 943  ELQQNQADLEQKNKKLYTEKKDLSKAFKEVSKLNSELQRSND--EKIRQN-SELANQISE 999

Query: 1451 LTYEKESELAILRLKMHENANHYETMQKESEI----ERVKLIEELNVKITESVSLNKQVA 1506
            L+ ++  EL+    ++ +  +      KE+ I    +  K  E  ++ I E+    KQ+ 
Sbjct: 1000 LS-KQNQELSKANAELAKQNSEVTRAFKEARILGSSDSHKNSEGKHLAI-EAAEQQKQIR 1057

Query: 1507 ELNKALEEEVAKTNEMQTALENQEIEI 1533
            +L K   +E+ K N+ Q  ++ QE+++
Sbjct: 1058 DLQKQ-NQELLKQNQ-QLLMQMQEVQL 1082



 Score = 56.8 bits (131), Expect = 5e-06
 Identities = 140/775 (18%), Positives = 318/775 (41%), Gaps = 62/775 (8%)

Query: 860  EENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIV 919
            ++NQN Q  ++   Q+ N + ++ N +    + S +     R+   N+ ++    Q ++ 
Sbjct: 165  QQNQNNQY-INRQSQYQNYMQQEQNISPQPRNHSNRSINNNRNNIDNIAQV----QNIVQ 219

Query: 920  QKKKEIEDLEI--EFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMN 977
            +++++++  +   +F     S  R+ +  N+   ++         Q   Y NN +  +  
Sbjct: 220  KQQQQLQQFQPHQQFGVIRASPYRNNENQNQGTSQSPYNNNNNNNQQSPYYNNRQQHSPY 279

Query: 978  VEELNKM----NLELIDK---HVQKQQTQSPDYTEQYINEINKL----NAL-------LK 1019
             ++L +       E ID+   HV ++   +    E Y  + NK+     A+       + 
Sbjct: 280  DDQLEQTYPTNENEDIDRQIVHVIRESKANRSEKEYYKYKYNKILKDKEAITMQTEYQMS 339

Query: 1020 QKDEEIIALNQKIN-----NAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDS 1074
            QK+EE+  L ++I      +  V + + +   E+++ Q  TK++ ++ ++  V K+  D 
Sbjct: 340  QKEEEVNYLKEQIQKLMQESRNVLHENKILSDENEVLQ--TKIKTLKAKLAEVEKKSADR 397

Query: 1075 KQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXX 1134
            K   +++  +++++DDQIK L+        N+      I  ++   ++  +N++      
Sbjct: 398  KASLKQVYSILQQKDDQIKMLQANNNNNNNNMNNFNNAIQQNSAS-LAAASNSIIINQIK 456

Query: 1135 XXXXXXXLKVQEE--EEFIQ-ERSVLQEQSAKLNTELQECYTKIIQLE-TLNTELTGHDV 1190
                    +V++    +F Q ER+V Q+     N E Q     + +   T N ++     
Sbjct: 457  DDFARQLAEVEKSFLNQFHQIERAVNQKNDIIANLEDQIKNLNLSKRNITSNNKIDLSSP 516

Query: 1191 VNQEQINQLKSKLEQLNTENDNLL--STVAELRSSISSAVD--QRGFEIAELWKQHLAQR 1246
            +     N    + +  NT N   L  +   +L +   + VD  Q    +    +Q + Q 
Sbjct: 517  IEFTLSNNTSKRNQNANTVNQEQLIRAKKMDLEAKRENLVDIIQNNPNLPTQKRQEIQQI 576

Query: 1247 EADFQKTEHEL-RVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEH 1305
             +       EL   Q +  + + +Q   SV SS   E NK    + +  L  ++Q +E  
Sbjct: 577  ISHINNQMIELIDYQATHPDVENDQEHGSVGSSNSLEGNK----QDIAEL--RMQIEEYC 630

Query: 1306 LRNLQEKYADVINQIEILRSEIEDEK-VAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQE 1364
             +N+  +  +   Q + L  E E EK +                  D+ T NQ+ + +  
Sbjct: 631  NKNIMLERENEQLQEQFLLKEKETEKFIGELQILLNQLRIQDQVQSDVETLNQNERNLVS 690

Query: 1365 QSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYT 1424
             SI N+ E    +K+              ++++ + ++LE   Q+ ++  E    T++  
Sbjct: 691  LSISNLGESLGAIKE---------VVNSYKMHENQIQLLEQQLQIAIQSQE--NLTNQLQ 739

Query: 1425 ITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIER 1484
              L   N +   + +QL    + ++ L  +++S  + L+ +        E ++ + +I R
Sbjct: 740  NNLISENSQKSEIIKQLDSQLQNLKSLLQQEQSINSDLQEENGRQRERIEQLRDQLDIFR 799

Query: 1485 VKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQ 1544
             K       K  +  S   Q ++L    +++  + NE+    +  E +I  +      ++
Sbjct: 800  QKDKSSQQSKYNDDNS--SQYSQLFSKYQQQQVQFNEVVRERDIIEQKIQEMQRNYKEVK 857

Query: 1545 NMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDLAMYMLHQR 1599
            +    S  + +K     SD +Q   +    + + E ++ + +   DL   +++Q+
Sbjct: 858  SKYEKSKDERKKMQKMISDQQQAITQLKKYSQSDEQVENLNQIINDLKNKLINQQ 912


>UniRef50_A2DA80 Cluster: Viral A-type inclusion protein, putative;
            n=1; Trichomonas vaginalis G3|Rep: Viral A-type inclusion
            protein, putative - Trichomonas vaginalis G3
          Length = 2250

 Score =  180 bits (437), Expect = 4e-43
 Identities = 269/1309 (20%), Positives = 569/1309 (43%), Gaps = 123/1309 (9%)

Query: 329  ELLEHLNCQIRQTNKELENKLATM-GTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWS 387
            EL+++    + + N +L  +L+++  + S  +S+  K+   L+S KSG  T   +K+  +
Sbjct: 195  ELMQN-KLNLEKENNKLSTQLSSLQSSSSDNISNLKKERDELVSIKSGILTVLGLKND-N 252

Query: 388  QLSSETLNQDTDKKINKNEIAKLEMVIQSLN---KDLVDKEYVISEKDTXXXXXXXXXXG 444
            Q+     N     KI +  I+ L    +  +   K L+     + E+             
Sbjct: 253  QIEPTINNLLNSHKILQQAISSLGCSPEKTHETIKQLIQHHQNLKEQQDAITKMLKSNPS 312

Query: 445  KDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEK 504
            +     Q  L+ +   E  +        +  N++   Q +L  + N  IK++  ++   K
Sbjct: 313  EIPSQIQNLLDAKNSSEKQAKNLKSELGKTTNKLLDAQNELNDKANS-IKNLEYENDQTK 371

Query: 505  --LKSAEEQITQLNDEIDAANKNMIKVKS----NHKLKLKQMQKTIDNFSKVSDSNKEIV 558
              +K   EQ+   N ++     ++   KS    N  LK   +Q   DN  +   SN+ + 
Sbjct: 372  QTVKRLNEQLADANRKLHETEVSLETTKSQLQQNENLK-SLIQSEYDNSRQ--HSNELVE 428

Query: 559  RLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRM-----IES--DVYKKMIE-MENLAE 610
            +LT+EL   S++  +L+ +   +   +   ++ +      IE+  ++   MIE + N   
Sbjct: 429  KLTQELTSKSEEATKLKSQVSEMLSRIQQAENTKQALQSSIETTRNMTNNMIEGLHNELN 488

Query: 611  TRLKAISLLESQKFDLVQELHI--------------LQQKYDEVEDKLADISQLQSDQVC 656
            ++   I+ L++Q   L +E  I              LQ   D  +D+L D     S ++ 
Sbjct: 489  SKNDEIAKLQAQNATLHREFEISQAKLQQTETQRKSLQDDLDSTQDQLNDTESKLSTEIS 548

Query: 657  SEIKSV-HLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQ 715
            ++ K + +L+ Q+D+++   +E+ + +E+     +Q     K  +  + ++ NKLQN I 
Sbjct: 549  TKDKEIANLKNQLDSVNKKNEEMEIQLESFNAKAKQYQNDFKSSQQKQTELENKLQNEIA 608

Query: 716  ENMDLTDKLEKM---SAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELS 772
            +  +   KL+     S  K ++    ++H        Q   +A  +     I+++ +E S
Sbjct: 609  QKTETIAKLQSKITESKRKQTDTANLLDHTSNQLKILQSEYEATKKNHSQAIKDLSAESS 668

Query: 773  KYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMD 832
            +    I RL   ++  +  + +LE         +Q + +A S+++    EL+  L    +
Sbjct: 669  EKTKEIGRLMNEVSAAKRAQLALENSKQT----IQAEYEASSKHS---SELIENLK-NEN 720

Query: 833  HDRVVEKQLLEIEHEN-KELQKKNQILLEENQN-LQISLSDMQQHYNALVEKANRT-DLA 889
              +V E   ++ E+EN K     N + L++N+  LQI  SD++     + +K N T    
Sbjct: 721  SQKVAELAKMKAENENLKRSNDVNNLKLKDNETALQILKSDLE----TIKQKNNETIGKL 776

Query: 890  ESESTKYQTQLRDLESNLKRITHEHQTL---IVQKKKEIEDLEIEFNTQIESAIRDKKVL 946
             SE ++   +  DL+SNL  +T ++  L   +   K +I   E+           +K+  
Sbjct: 777  TSEISEKSKENLDLKSNLADMTRQNTELNSQVETLKSQISQNEVLKKLMENEYANNKEET 836

Query: 947  NEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQ 1006
             +   K ++  T+   ++ + K  I NL+   +++N  N++ ++  V    + + +    
Sbjct: 837  QQFLAKAVQENTEKTKEINDLKAEISNLSSKNQQMNS-NIDSLNSQVSNLTSSNEELKNN 895

Query: 1007 YINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQR 1066
            Y   +      ++ K +EI  L +K  N++++  S +S  ++++A+ T  LE + E   +
Sbjct: 896  YQKLVESSEQTIQGKIKEISDLKEK--NSKLN--SNISLKDAEIAENTKNLEALHENAAK 951

Query: 1067 VSKQLLDSKQHNEELQILVREQDDQIKELKETK--LTFEMNIPKTEGMIISSTIEPMSDD 1124
              K LL  KQ  E+++    E  +  + L ETK  L  ++ + K    I    I+ ++D 
Sbjct: 952  --KDLL-VKQLQEQIRNDKNEIANLTQTLDETKSSLNHDIIVLKNSNDIKDQQIQSLNDH 1008

Query: 1125 ANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTE 1184
             N+++             K +  E+  Q    L++++ KLN +LQ    +I +L     E
Sbjct: 1009 INSLNDTSMNAVNEQINAKQKLSEQITQ----LEDENNKLNNQLQSDKIEISKLNVALGE 1064

Query: 1185 LTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSS----ISSAVDQRGFEIAELWK 1240
                    Q  I++    +++ N +  +L   + ++  S    I++   Q   EI+++  
Sbjct: 1065 KDSLAAAKQNVIDEQNVTIQKQNKKIADLQGDIGKMNISHEDEIANIKLQHVKEISDIKA 1124

Query: 1241 QHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQ 1300
            QH+ +     Q+T+  +   +S  + KY Q      +  Q++ NK+     ++S Q  + 
Sbjct: 1125 QHIKELADKEQETKKLIESIISDNQQKYSQ----SSNELQDKLNKL-----MSSSQEIIS 1175

Query: 1301 DKEEHLRNLQEKYADVINQIE-ILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSY 1359
            +K++ +  ++EK+ + ++ ++  LRSE E+ +                   +LR +    
Sbjct: 1176 EKQKEISEMKEKHQNEMSLLQNNLRSEKENLRAEKDKEISDLKDKYDLELSNLRLKLNQL 1235

Query: 1360 KQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQL-ELKDSEIYQ 1418
               +++ I ++NE++                    ++D E  + +  +Q+ + K  EI +
Sbjct: 1236 NSSKDKEISDLNEKH-----------------HNEISDLEKNLRDEMNQMQQAKKDEINE 1278

Query: 1419 KTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQK 1478
               +    L+Q   E+  ++Q      K I DL  +  +E+  L+       N ++    
Sbjct: 1279 LREKQRQELSQSRTEYSQLQQNSA---KEISDLNEKHHNEMKDLQ-------NSFKQEMD 1328

Query: 1479 ESEIERVKLIEELNVKITE-SVSLNKQVAELNKALEEEVA-KTNEMQTALENQEIEIVTL 1536
            + +  + K I+ELN K+ +  +S + +++EL +  + E + K+ E+    +    EI +L
Sbjct: 1329 KLQDAKTKEIQELNDKLNQLQLSKSNEISELKEKQQNEFSLKSKEISGIKQKHHQEIDSL 1388

Query: 1537 N----DEITNLQ-NMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKEL 1580
            N    +EI N+Q N V    +   +H     D +      +D   N++L
Sbjct: 1389 NEKHLEEIENMQVNHVNELQTLKDQHHQQILDLQNQSRIDMDLVKNQKL 1437



 Score =  139 bits (337), Expect = 5e-31
 Identities = 282/1456 (19%), Positives = 601/1456 (41%), Gaps = 145/1456 (9%)

Query: 215  KQQMTKMQENFI-AMEAEWKDEKQRLLKDIESKDVRISSLEEANKL---LEAARFEISLE 270
            KQ   K  EN    +  +  D+   LL+++    + +   +E NKL   L + +   S  
Sbjct: 167  KQLYQKQLENITKTINCKDADKIPTLLQELMQNKLNLE--KENNKLSTQLSSLQSSSSDN 224

Query: 271  HSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKI-E 329
             S L +E ++                   IEP+        +     I+++    +K  E
Sbjct: 225  ISNLKKERDELVSIKSGILTVLGLKNDNQIEPTINNLLNSHKILQQAISSLGCSPEKTHE 284

Query: 330  LLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQL 389
             ++ L  Q  Q  KE ++ +  M  +S     PS+  + L ++ S    A  +KS   + 
Sbjct: 285  TIKQL-IQHHQNLKEQQDAITKM-LKSNPSEIPSQIQNLLDAKNSSEKQAKNLKSELGKT 342

Query: 390  SSETLNQDTDKKINKNEIAKLE-------MVIQSLNKDLVDKEYVISEKDTXXXXXXXXX 442
            +++ L+   +     N I  LE         ++ LN+ L D    + E +          
Sbjct: 343  TNKLLDAQNELNDKANSIKNLEYENDQTKQTVKRLNEQLADANRKLHETEVSLETTKSQL 402

Query: 443  XGKDTLIAQLQLEHQQHMEGPS-LIHVGTN--TEDVNEIAKVQEQLKQELNDEIKDVNVK 499
               + L + +Q E+    +  + L+   T   T    E  K++ Q+ + L+   +  N K
Sbjct: 403  QQNENLKSLIQSEYDNSRQHSNELVEKLTQELTSKSEEATKLKSQVSEMLSRIQQAENTK 462

Query: 500  DLIEKLKSAEEQITQ-----LNDEIDAANKNMIKVKSNH----------KLKLKQMQKTI 544
              ++        +T      L++E+++ N  + K+++ +          + KL+Q +   
Sbjct: 463  QALQSSIETTRNMTNNMIEGLHNELNSKNDEIAKLQAQNATLHREFEISQAKLQQTETQR 522

Query: 545  DNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNL--QLHLVDYDSGRM---IESDVY 599
             +     DS ++ +  TE    LS +++  ++E  NL  QL  V+  +  M   +ES   
Sbjct: 523  KSLQDDLDSTQDQLNDTES--KLSTEISTKDKEIANLKNQLDSVNKKNEEMEIQLESFNA 580

Query: 600  KKMIEMENLAETRLKAISLLESQKFDLVQELHI---LQQKYDEVEDKLADISQLQSDQVC 656
            K      +   ++ K   L    + ++ Q+      LQ K  E + K  D + L  D   
Sbjct: 581  KAKQYQNDFKSSQQKQTELENKLQNEIAQKTETIAKLQSKITESKRKQTDTANLL-DHTS 639

Query: 657  SEIKSVHLE---------EQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIM 707
            +++K +  E         + I  LSA   E    I  L  +          LEN K+ I 
Sbjct: 640  NQLKILQSEYEATKKNHSQAIKDLSAESSEKTKEIGRLMNEVSAAKRAQLALENSKQTIQ 699

Query: 708  NKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENI 767
             + +   + + +L + L+  +++K++EL AK+  E ++  ++    + K+++ +  ++ +
Sbjct: 700  AEYEASSKHSSELIENLKNENSQKVAEL-AKMKAENENLKRSNDVNNLKLKDNETALQIL 758

Query: 768  ESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRL 827
            +S+L   K +     E+I  +        ++   L S L +  +  +E   Q + L +++
Sbjct: 759  KSDLETIKQKN---NETIGKLTSEISEKSKENLDLKSNLADMTRQNTELNSQVETLKSQI 815

Query: 828  AVLMDHDRVVEKQLLEIEHEN--KELQKKNQILLEENQNLQISLSDMQQHYNALVEKANR 885
            +        V K+L+E E+ N  +E Q+     ++EN      ++D++   + L  K  +
Sbjct: 816  S-----QNEVLKKLMENEYANNKEETQQFLAKAVQENTEKTKEINDLKAEISNLSSKNQQ 870

Query: 886  T----DLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIES--A 939
                 D   S+ +   +   +L++N +++    +  I  K KEI DL+ E N+++ S  +
Sbjct: 871  MNSNIDSLNSQVSNLTSSNEELKNNYQKLVESSEQTIQGKIKEISDLK-EKNSKLNSNIS 929

Query: 940  IRDKKV---------LNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEEL-NKMNLELI 989
            ++D ++         L+E   K    V QL+ Q++  KN I NL   ++E  + +N ++I
Sbjct: 930  LKDAEIAENTKNLEALHENAAKKDLLVKQLQEQIRNDKNEIANLTQTLDETKSSLNHDII 989

Query: 990  DKHVQKQQTQSPDYTEQYINE-INKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYES 1048
               V K      D   Q +N+ IN LN      D  + A+N++IN A+      ++  E 
Sbjct: 990  ---VLKNSNDIKDQQIQSLNDHINSLN------DTSMNAVNEQIN-AKQKLSEQITQLED 1039

Query: 1049 KLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPK 1108
            +  +   +L++ + E+ +++  L +        Q ++ EQ+  I++  +     + +I K
Sbjct: 1040 ENNKLNNQLQSDKIEISKLNVALGEKDSLAAAKQNVIDEQNVTIQKQNKKIADLQGDIGK 1099

Query: 1109 TEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTEL 1168
               M IS   E  +    +V             L  +E+E      S++ +   K +   
Sbjct: 1100 ---MNISHEDEIANIKLQHVKEISDIKAQHIKELADKEQETKKLIESIISDNQQKYSQSS 1156

Query: 1169 QECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLE-QLNTENDNLLSTVAELRSS---- 1223
             E   K+ +L + + E+       Q++I+++K K + +++   +NL S    LR+     
Sbjct: 1157 NELQDKLNKLMSSSQEIISE---KQKEISEMKEKHQNEMSLLQNNLRSEKENLRAEKDKE 1213

Query: 1224 ISSAVDQRGFEIAEL---WKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQ 1280
            IS   D+   E++ L     Q  + ++ +      +   ++S  E      ++ +Q + +
Sbjct: 1214 ISDLKDKYDLELSNLRLKLNQLNSSKDKEISDLNEKHHNEISDLEKNLRDEMNQMQQAKK 1273

Query: 1281 EETNKIVTMEQVTSLQNKL------QDKEEHLRNLQEKY----ADVINQIEILRSEIEDE 1330
            +E N++   ++    Q++       Q+  + + +L EK+     D+ N  +    +++D 
Sbjct: 1274 DEINELREKQRQELSQSRTEYSQLQQNSAKEISDLNEKHHNEMKDLQNSFKQEMDKLQDA 1333

Query: 1331 KVA----FXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKS--SXXX 1384
            K                       +L+ + Q+   ++ + I  I +++ Q   S      
Sbjct: 1334 KTKEIQELNDKLNQLQLSKSNEISELKEKQQNEFSLKSKEISGIKQKHHQEIDSLNEKHL 1393

Query: 1385 XXXXXXXXXRVNDAEA-------KVLELTHQLELK-DSEIYQKTHEYTITLTQRNDEFEN 1436
                      VN+ +        ++L+L +Q  +  D    QK  E T    + +DE E 
Sbjct: 1394 EEIENMQVNHVNELQTLKDQHHQQILDLQNQSRIDMDLVKNQKLKEITELNKKHHDELEK 1453

Query: 1437 VRQQLVEYEKRIEDLTYEKESELAILRLKMHE--------NANHYETMQKESEIERVKLI 1488
            ++   +++   ++ +  +K  E+  +  K HE        + N  + +QK  + E   L+
Sbjct: 1454 LQ---IDHRIELDQMNSQKLKEITAMNDKHHEEIIAIQNSSRNELDKIQKTRQQEVSGLM 1510

Query: 1489 EELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVR 1548
             +    + E+    + + + N +L+ E      +++ LEN  ++I   + E+T +Q+   
Sbjct: 1511 AQRAKDLQENTKTIENLKKENSSLQVE---NKTLKSQLENIRLQIKETSKELTEMQSAFS 1567

Query: 1549 ASSSKIQKHVSFASDT 1564
              S    + +S    T
Sbjct: 1568 NRSRVFDESLSLMRST 1583



 Score =  131 bits (316), Expect = 2e-28
 Identities = 259/1214 (21%), Positives = 526/1214 (43%), Gaps = 130/1214 (10%)

Query: 447  TLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKV-QEQLKQELNDEIKDVNVKDLIEKL 505
            ++++ L  E Q + +    I    N +D ++I  + QE ++ +LN E ++  +   +  L
Sbjct: 158  SVVSNLLQEKQLYQKQLENITKTINCKDADKIPTLLQELMQNKLNLEKENNKLSTQLSSL 217

Query: 506  KSAE-EQITQLNDEIDAANKNMIKVKSN--HKLKLKQMQKTIDNFSKVSDSNKEIVRLTE 562
            +S+  + I+ L  E D     ++ +KS     L LK   +     + + +S+K + +   
Sbjct: 218  QSSSSDNISNLKKERD----ELVSIKSGILTVLGLKNDNQIEPTINNLLNSHKILQQAIS 273

Query: 563  ELHHLSQKVAELEEEKGNLQLHLVDYDSG--RMIESDVYKKMIEMENLAETRLKAISLLE 620
             L    +K  E  ++      +L +      +M++S+  +   +++NL + +  +    +
Sbjct: 274  SLGCSPEKTHETIKQLIQHHQNLKEQQDAITKMLKSNPSEIPSQIQNLLDAKNSSEKQAK 333

Query: 621  SQKFDLVQELHILQQKYDEVEDKLADISQL--QSDQVCSEIKSVHLEEQIDALSASKKEL 678
            + K +L +  + L    +E+ DK   I  L  ++DQ    +K   L EQ+   +    E 
Sbjct: 334  NLKSELGKTTNKLLDAQNELNDKANSIKNLEYENDQTKQTVK--RLNEQLADANRKLHET 391

Query: 679  ALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENM--DLTDKLEKMSAEK--ISE 734
             + +E  K   +Q    +K L   + D   +  N + E +  +LT K E+ +  K  +SE
Sbjct: 392  EVSLETTKSQLQQ-NENLKSLIQSEYDNSRQHSNELVEKLTQELTSKSEEATKLKSQVSE 450

Query: 735  LLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVM------ 788
            +L++I   E +K   Q  I+      +  IE + +EL+     I +L+   A +      
Sbjct: 451  MLSRIQQAENTKQALQSSIETTRNMTNNMIEGLHNELNSKNDEIAKLQAQNATLHREFEI 510

Query: 789  --------EDRRYSLERKADQLGSYLQE-KQKAYSEYTIQEDELVNRLAVLMDHDRVVEK 839
                    E +R SL+   D     L + + K  +E + ++ E+ N    L   ++  E+
Sbjct: 511  SQAKLQQTETQRKSLQDDLDSTQDQLNDTESKLSTEISTKDKEIANLKNQLDSVNKKNEE 570

Query: 840  QLLEIEHENKELQKKNQILLEENQNLQISLSD-MQQHYNALVEKANRTDLAESESTKYQT 898
              +++E  N +  K+ Q   + +Q  Q  L + +Q       E   +     +ES + QT
Sbjct: 571  MEIQLESFNAK-AKQYQNDFKSSQQKQTELENKLQNEIAQKTETIAKLQSKITESKRKQT 629

Query: 899  ---QLRDLESN-LKRITHEHQTLIVQKKKEIEDLEIEFN----------TQIESAIR--- 941
                L D  SN LK +  E++       + I+DL  E +           ++ +A R   
Sbjct: 630  DTANLLDHTSNQLKILQSEYEATKKNHSQAIKDLSAESSEKTKEIGRLMNEVSAAKRAQL 689

Query: 942  ----DKKVLNEKYEKNIEYVTQLEAQLQ-EYKNNIENL------NMNVEELNKM-NLELI 989
                 K+ +  +YE + ++ ++L   L+ E    +  L      N N++  N + NL+L 
Sbjct: 690  ALENSKQTIQAEYEASSKHSSELIENLKNENSQKVAELAKMKAENENLKRSNDVNNLKLK 749

Query: 990  DKHVQKQQTQSP-DYTEQYINE-INKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYE 1047
            D     Q  +S  +  +Q  NE I KL + + +K +E   L+ K N A ++  +  ++  
Sbjct: 750  DNETALQILKSDLETIKQKNNETIGKLTSEISEKSKE--NLDLKSNLADMTRQN--TELN 805

Query: 1048 SKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEE-LQILVREQDDQIKELKETKLTFEMNI 1106
            S++    +++   E   + +  +  ++K+  ++ L   V+E  ++ KE+ + K   E++ 
Sbjct: 806  SQVETLKSQISQNEVLKKLMENEYANNKEETQQFLAKAVQENTEKTKEINDLKA--EISN 863

Query: 1107 PKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEF---IQERSVLQEQSAK 1163
              ++   ++S I+ ++   +N+             L    E+     I+E S L+E+++K
Sbjct: 864  LSSKNQQMNSNIDSLNSQVSNLTSSNEELKNNYQKLVESSEQTIQGKIKEISDLKEKNSK 923

Query: 1164 LNTELQECYTKIIQLETLNTELTGHDVVNQE-QINQLKSKLEQLNTENDNLLSTVAELRS 1222
            LN+ +     +I +  T N E    +   ++  + QL+ ++     E  NL  T+ E +S
Sbjct: 924  LNSNISLKDAEIAE-NTKNLEALHENAAKKDLLVKQLQEQIRNDKNEIANLTQTLDETKS 982

Query: 1223 SISSAV-------DQRGFEIAELWKQHL------AQREADFQ-KTEHELRVQLSAFESKY 1268
            S++  +       D +  +I  L   H+      +    + Q   + +L  Q++  E + 
Sbjct: 983  SLNHDIIVLKNSNDIKDQQIQSL-NDHINSLNDTSMNAVNEQINAKQKLSEQITQLEDEN 1041

Query: 1269 EQLLDSVQSSTQEETNKIVTMEQVTSL----QNKLQDKEEHLRNLQEKYADVINQIEILR 1324
             +L + +QS   E +   V + +  SL    QN + ++   ++   +K AD+   I  + 
Sbjct: 1042 NKLNNQLQSDKIEISKLNVALGEKDSLAAAKQNVIDEQNVTIQKQNKKIADLQGDIGKMN 1101

Query: 1325 SEIEDEKVAF-XXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXX 1383
               EDE                     +L  + Q  K++ E SI++ N++  +  +SS  
Sbjct: 1102 ISHEDEIANIKLQHVKEISDIKAQHIKELADKEQETKKLIE-SIISDNQQ--KYSQSS-- 1156

Query: 1384 XXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRN--DEFENVRQQL 1441
                      ++N   +   E+  + + + SE+ +K H+  ++L Q N   E EN+R   
Sbjct: 1157 -----NELQDKLNKLMSSSQEIISEKQKEISEMKEK-HQNEMSLLQNNLRSEKENLR--- 1207

Query: 1442 VEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVS- 1500
             E +K I DL  + + EL+ LRLK+++         K+ E      I +LN K    +S 
Sbjct: 1208 AEKDKEISDLKDKYDLELSNLRLKLNQ-----LNSSKDKE------ISDLNEKHHNEISD 1256

Query: 1501 LNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNL-QNMVRASSSKIQKHVS 1559
            L K + +    +++  AK +E+    E Q  E+     E + L QN  +  S   +KH +
Sbjct: 1257 LEKNLRDEMNQMQQ--AKKDEINELREKQRQELSQSRTEYSQLQQNSAKEISDLNEKHHN 1314

Query: 1560 FASDTKQGRDEQLD 1573
               D +    +++D
Sbjct: 1315 EMKDLQNSFKQEMD 1328



 Score =  120 bits (288), Expect = 4e-25
 Identities = 249/1204 (20%), Positives = 498/1204 (41%), Gaps = 95/1204 (7%)

Query: 160  VLQVKMKIMETTILDLQEKINE-KDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQM 218
            + Q K++  ET    LQ+ ++  +DQ+ + ++K +T                    K   
Sbjct: 510  ISQAKLQQTETQRKSLQDDLDSTQDQLNDTESKLSTEISTKDKEIANLKNQLDSVNK--- 566

Query: 219  TKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFE-ISLEHSKLAQE 277
             K +E  I +E+ +  + ++   D +S   + + LE   +   A + E I+   SK+ + 
Sbjct: 567  -KNEEMEIQLES-FNAKAKQYQNDFKSSQQKQTELENKLQNEIAQKTETIAKLQSKITES 624

Query: 278  LEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQ 337
              +              L     E    +K   +    L  A  +E TK+I  L +    
Sbjct: 625  KRKQTDTANLLDHTSNQLKILQSEYEATKKNHSQAIKDLS-AESSEKTKEIGRLMNEVSA 683

Query: 338  IRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQD 397
             ++    LEN   T+  E +A    SK  S LI      N+    +    +  +E L + 
Sbjct: 684  AKRAQLALENSKQTIQAEYEA---SSKHSSELIENLKNENSQKVAELAKMKAENENLKRS 740

Query: 398  TD---KKINKNEIA------KLEMVIQSLNKDLVDKEYVISEK---DTXXXXXXXXXXGK 445
             D    K+  NE A       LE + Q  N+ +      ISEK   +            +
Sbjct: 741  NDVNNLKLKDNETALQILKSDLETIKQKNNETIGKLTSEISEKSKENLDLKSNLADMTRQ 800

Query: 446  DT-LIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLK---QELNDEIKDVNVKDL 501
            +T L +Q++    Q  +   L  +  N E  N   + Q+ L    QE  ++ K++N  DL
Sbjct: 801  NTELNSQVETLKSQISQNEVLKKLMEN-EYANNKEETQQFLAKAVQENTEKTKEIN--DL 857

Query: 502  IEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSK-VSDSNKEIVRL 560
              ++ +   +  Q+N  ID+ N  +  + S+++      QK +++  + +    KEI  L
Sbjct: 858  KAEISNLSSKNQQMNSNIDSLNSQVSNLTSSNEELKNNYQKLVESSEQTIQGKIKEISDL 917

Query: 561  TEE----LHHLSQKVAELEEEKGNLQ-LH--LVDYD-SGRMIESDVYKKMIEMENLAETR 612
             E+      ++S K AE+ E   NL+ LH      D   + ++  +     E+ NL +T 
Sbjct: 918  KEKNSKLNSNISLKDAEIAENTKNLEALHENAAKKDLLVKQLQEQIRNDKNEIANLTQTL 977

Query: 613  LKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVH-LEEQIDAL 671
             +  S L      L     I  Q+   + D +  ++    + V  +I +   L EQI  L
Sbjct: 978  DETKSSLNHDIIVLKNSNDIKDQQIQSLNDHINSLNDTSMNAVNEQINAKQKLSEQITQL 1037

Query: 672  SASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEK 731
                 +L   +++ K++  +L   +     +K+ +    QN I E      K  K  A+ 
Sbjct: 1038 EDENNKLNNQLQSDKIEISKLNVAL----GEKDSLAAAKQNVIDEQNVTIQKQNKKIADL 1093

Query: 732  ISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDR 791
              + + K+N   + +I     +    +  D+  ++I+ EL+  +    +L ESI     +
Sbjct: 1094 QGD-IGKMNISHEDEI-ANIKLQHVKEISDIKAQHIK-ELADKEQETKKLIESIISDNQQ 1150

Query: 792  RYS-----LERKADQLGS----YLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLL 842
            +YS     L+ K ++L S     + EKQK  SE    +++  N +++L ++ R  EK+ L
Sbjct: 1151 KYSQSSNELQDKLNKLMSSSQEIISEKQKEISE---MKEKHQNEMSLLQNNLR-SEKENL 1206

Query: 843  EIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRD 902
              E + +    K++  LE + NL++ L+ +    +  +   N  +   +E +  +  LRD
Sbjct: 1207 RAEKDKEISDLKDKYDLELS-NLRLKLNQLNSSKDKEISDLN--EKHHNEISDLEKNLRD 1263

Query: 903  LESNLKRI-THEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLE 961
              + +++    E   L  ++++E+     E++   +++ ++   LNEK+   ++    L+
Sbjct: 1264 EMNQMQQAKKDEINELREKQRQELSQSRTEYSQLQQNSAKEISDLNEKHHNEMK---DLQ 1320

Query: 962  AQLQEYKNNIENL-NMNVEELN-KMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLK 1019
               ++  + +++     ++ELN K+N   + K  +  + +     E +  +  +++ + +
Sbjct: 1321 NSFKQEMDKLQDAKTKEIQELNDKLNQLQLSKSNEISELKEKQQNE-FSLKSKEISGIKQ 1379

Query: 1020 QKDEEIIALNQK----INNAQVSYMSMVSDYESKLAQFTTKLENMEE-EMQRVSKQLLD- 1073
            +  +EI +LN+K    I N QV++++ +   + +  Q    L+N    +M  V  Q L  
Sbjct: 1380 KHHQEIDSLNEKHLEEIENMQVNHVNELQTLKDQHHQQILDLQNQSRIDMDLVKNQKLKE 1439

Query: 1074 ----SKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVD 1129
                +K+H++EL+ L  +   ++ ++   KL     I           I   +   N +D
Sbjct: 1440 ITELNKKHHDELEKLQIDHRIELDQMNSQKL---KEITAMNDKHHEEIIAIQNSSRNELD 1496

Query: 1130 XXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQ-ECYTKIIQLETLNTELTGH 1188
                        L  Q  ++ +QE +   E   K N+ LQ E  T   QLE +  ++   
Sbjct: 1497 KIQKTRQQEVSGLMAQRAKD-LQENTKTIENLKKENSSLQVENKTLKSQLENIRLQIKET 1555

Query: 1189 DVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREA 1248
                 E  +   ++    +     + ST+ ++R  +    D    EIA      +     
Sbjct: 1556 SKELTEMQSAFSNRSRVFDESLSLMRSTLEKIRMILGLPADVSVEEIA----SSVDNLMK 1611

Query: 1249 DFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTS---LQNKLQDKEEH 1305
            +F K  H+L V   A +      L  ++    E +    +++++T+   LQN      EH
Sbjct: 1612 NFAK--HQLEV-CKALDLPKRSPLKEIRGKINELSGTSHSLQEITTNLGLQNSPDAINEH 1668

Query: 1306 LRNL 1309
            ++ L
Sbjct: 1669 IKTL 1672



 Score = 94.3 bits (224), Expect = 2e-17
 Identities = 224/1197 (18%), Positives = 491/1197 (41%), Gaps = 94/1197 (7%)

Query: 145  THLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXX 204
            T L++ ++   + +S  +V  K+ME    + +E+  +       +N   T          
Sbjct: 802  TELNSQVETLKSQISQNEVLKKLMENEYANNKEETQQFLAKAVQENTEKTKEINDLKAEI 861

Query: 205  XXXXXXXEDTKQQMTKMQE---NFIAMEAEWKDEKQRLLKD----IESKDVRISSLEEAN 257
                   +     +  +     N  +   E K+  Q+L++     I+ K   IS L+E N
Sbjct: 862  SNLSSKNQQMNSNIDSLNSQVSNLTSSNEELKNNYQKLVESSEQTIQGKIKEISDLKEKN 921

Query: 258  KLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLE 317
              L +    ISL+ +++A+  +               L KQ  E    +K EI       
Sbjct: 922  SKLNS---NISLKDAEIAENTKNLEALHENAAKKDL-LVKQLQEQIRNDKNEI------- 970

Query: 318  IANMTE-LTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGR 376
             AN+T+ L +    L H    ++ +N   + ++ ++     +++  S      ++ +   
Sbjct: 971  -ANLTQTLDETKSSLNHDIIVLKNSNDIKDQQIQSLNDHINSLNDTSMNA---VNEQI-- 1024

Query: 377  NTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXX 436
            N   K+    +QL  E    +   + +K EI+KL + +   +     K+ VI E++    
Sbjct: 1025 NAKQKLSEQITQLEDENNKLNNQLQSDKIEISKLNVALGEKDSLAAAKQNVIDEQNVTIQ 1084

Query: 437  XXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDV 496
                        I ++ + H+  +    L HV        EI+ ++ Q  +EL D  K+ 
Sbjct: 1085 KQNKKIADLQGDIGKMNISHEDEIANIKLQHV-------KEISDIKAQHIKELAD--KEQ 1135

Query: 497  NVKDLIEKLKSAEEQ-ITQLNDEI-DAANKNMI---KVKSNHKLKLKQMQKTIDNFSKVS 551
              K LIE + S  +Q  +Q ++E+ D  NK M    ++ S  + ++ +M++   N   + 
Sbjct: 1136 ETKKLIESIISDNQQKYSQSSNELQDKLNKLMSSSQEIISEKQKEISEMKEKHQNEMSLL 1195

Query: 552  DSN----KEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIE-SDVYKKMI-EM 605
             +N    KE +R  E+   +S    + + E  NL+L L   +S +  E SD+ +K   E+
Sbjct: 1196 QNNLRSEKENLR-AEKDKEISDLKDKYDLELSNLRLKLNQLNSSKDKEISDLNEKHHNEI 1254

Query: 606  ENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQV--CSEIKSVH 663
             +L +     ++ ++  K D + EL   Q++  E+     + SQLQ +     S++   H
Sbjct: 1255 SDLEKNLRDEMNQMQQAKKDEINELREKQRQ--ELSQSRTEYSQLQQNSAKEISDLNEKH 1312

Query: 664  LEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDK 723
              E  D  ++ K+E+  + +    + ++L   +  L+  K + +++L+   Q    L  K
Sbjct: 1313 HNEMKDLQNSFKQEMDKLQDAKTKEIQELNDKLNQLQLSKSNEISELKEKQQNEFSLKSK 1372

Query: 724  LEKMSAEKISELLAKINHEEQSKIQT-QFGIDAKIQE-RDLYIENI-----ESELSKYKS 776
                  +K  + +  +N +   +I+  Q     ++Q  +D + + I     +S +     
Sbjct: 1373 EISGIKQKHHQEIDSLNEKHLEEIENMQVNHVNELQTLKDQHHQQILDLQNQSRIDMDLV 1432

Query: 777  RICRLEESIAVMEDRRYSLER-KADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDR 835
            +  +L+E   + +     LE+ + D      Q   +   E T   D+    +  + +  R
Sbjct: 1433 KNQKLKEITELNKKHHDELEKLQIDHRIELDQMNSQKLKEITAMNDKHHEEIIAIQNSSR 1492

Query: 836  -VVEKQLLEIEHENKELQKKNQILLEEN----QNLQISLSDMQQHYNALVEKANRTDLAE 890
              ++K     + E   L  +    L+EN    +NL+   S +Q     L  +     L  
Sbjct: 1493 NELDKIQKTRQQEVSGLMAQRAKDLQENTKTIENLKKENSSLQVENKTLKSQLENIRLQI 1552

Query: 891  SESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIE-DLEIEFNTQIESAIRDKKVLNEK 949
             E++K  T+++   SN  R+  E  +L+    ++I   L +  +  +E        L + 
Sbjct: 1553 KETSKELTEMQSAFSNRSRVFDESLSLMRSTLEKIRMILGLPADVSVEEIASSVDNLMKN 1612

Query: 950  YEKN-IEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYI 1008
            + K+ +E    L+      ++ ++ +   + EL+  +  L +         SPD   ++ 
Sbjct: 1613 FAKHQLEVCKALDL---PKRSPLKEIRGKINELSGTSHSLQEITTNLGLQNSPDAINEH- 1668

Query: 1009 NEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVS 1068
              I  L+ + ++ + E+     +  + Q+S +++    E   +Q   +++ + EE   + 
Sbjct: 1669 --IKTLHGVCRKLESEV-----RKRDTQLSGIAISLGAEDP-SQIDNQIQTILEENDNLK 1720

Query: 1069 KQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNV 1128
             ++  S+ +N+ L   +   +++  +    +L  + +  +     ++  +   +DD    
Sbjct: 1721 TEIDVSQMNNKSLCSTLGVDEEENVDRHVDRLIRDKSQMERAQKKLAELVGVENDD---- 1776

Query: 1129 DXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGH 1188
            +             + QE+   I     +++  + L+ + +E  +     E++N +  G 
Sbjct: 1777 NSSAVVYQKVAQMQRTQEQLTKILGTENIEDAVSDLHKQSEELNS---IFESVNNDENGS 1833

Query: 1189 DVVNQEQINQLKSKLEQLNTENDNLLSTVAELRS--SISSAVD-QRGFEIAELWKQHLAQ 1245
             V    Q +  K  + QL T+N NL S +AE+    ++S+  D +R         + L +
Sbjct: 1834 IVY---QASSQKEIVGQLITKNGNLSSQMAEIGKLMNVSTFQDIKRAINFLLSENERLTK 1890

Query: 1246 READFQKTEHELRVQLSA----FESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNK 1298
             EAD  +   ++   +        +  + +L +V+++    T    +++Q T L +K
Sbjct: 1891 TEADGIELRQQIADIIDTPGILDTTNNDMILAAVRNTKNSLTETKESLDQQTKLMSK 1947



 Score = 68.1 bits (159), Expect = 2e-09
 Identities = 151/778 (19%), Positives = 310/778 (39%), Gaps = 72/778 (9%)

Query: 806  LQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNL 865
            LQ + +   +     D+L+      M   +  E+Q   IE      QK    LLE+N+NL
Sbjct: 23   LQVRDEINDQLQTTFDDLIGDKIQAMRLKKQTEEQQKAIEKLKTINQKLKTELLEKNKNL 82

Query: 866  QISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEI 925
             + L+         +E+  R        + +   +     +      ++  +I Q  K  
Sbjct: 83   NLVLNLFDIPDQISLEELERMVKNMKLHSDFYDLIAKAFGDKSEDNKDYSPIIAQLLKIF 142

Query: 926  EDLEIEFNT---QIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELN 982
             DL+    T   +I S + +     + Y+K +E +T+     ++  + I  L   + + N
Sbjct: 143  GDLKNSLQTDDDKIASVVSNLLQEKQLYQKQLENITK-TINCKD-ADKIPTLLQELMQ-N 199

Query: 983  KMNLELIDKHVQKQQTQSPDYTEQYINEINK-LNALLKQKDEEIIALNQKINNAQVSYMS 1041
            K+NLE  +  +  Q +     +   I+ + K  + L+  K   +  L  K +N     ++
Sbjct: 200  KLNLEKENNKLSTQLSSLQSSSSDNISNLKKERDELVSIKSGILTVLGLKNDNQIEPTIN 259

Query: 1042 MVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLT 1101
             + +    L Q  + L    E+     KQL+   QH++ L    +EQ D I     TK+ 
Sbjct: 260  NLLNSHKILQQAISSLGCSPEKTHETIKQLI---QHHQNL----KEQQDAI-----TKML 307

Query: 1102 FEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQS 1161
                  K+    I S I+ + D  N+ +               +   + +  ++ L +++
Sbjct: 308  ------KSNPSEIPSQIQNLLDAKNSSEKQAKNLKSELG----KTTNKLLDAQNELNDKA 357

Query: 1162 AKL-NTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAEL 1220
              + N E +   TK   ++ LN +L   +    E    L++   QL  +N+NL S +   
Sbjct: 358  NSIKNLEYENDQTK-QTVKRLNEQLADANRKLHETEVSLETTKSQLQ-QNENLKSLI--- 412

Query: 1221 RSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQ 1280
            +S   ++  Q   E+ E   Q L  +  +  K + ++   LS  + + E    ++QSS  
Sbjct: 413  QSEYDNS-RQHSNELVEKLTQELTSKSEEATKLKSQVSEMLSRIQ-QAENTKQALQSSI- 469

Query: 1281 EETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXX 1340
             ET + +T   +  L N+L  K + +  LQ + A +  + EI +++++  +         
Sbjct: 470  -ETTRNMTNNMIEGLHNELNSKNDEIAKLQAQNATLHREFEISQAKLQQTE--------- 519

Query: 1341 XXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEA 1400
                         T+ +S +   + +   +N+  ++L                +++    
Sbjct: 520  -------------TQRKSLQDDLDSTQDQLNDTESKLSTEISTKDKEIANLKNQLDSVNK 566

Query: 1401 KVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFEN-----VRQQLVEYEKRIEDLTYEK 1455
            K  E+  QLE  +++  Q  +++  +  Q+  E EN     + Q+     K    +T  K
Sbjct: 567  KNEEMEIQLESFNAKAKQYQNDFK-SSQQKQTELENKLQNEIAQKTETIAKLQSKITESK 625

Query: 1456 ESELAILRLKMHENANHYETMQKESEIER---VKLIEELNVKITESV-SLNKQVAELNKA 1511
              +     L  H  +N  + +Q E E  +    + I++L+ + +E    + + + E++ A
Sbjct: 626  RKQTDTANLLDH-TSNQLKILQSEYEATKKNHSQAIKDLSAESSEKTKEIGRLMNEVSAA 684

Query: 1512 LEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRD 1569
               ++A  N  QT     E      ++ I NL+N      +++ K  +   + K+  D
Sbjct: 685  KRAQLALENSKQTIQAEYEASSKHSSELIENLKNENSQKVAELAKMKAENENLKRSND 742


>UniRef50_A2FQ08 Cluster: Viral A-type inclusion protein, putative;
            n=1; Trichomonas vaginalis G3|Rep: Viral A-type inclusion
            protein, putative - Trichomonas vaginalis G3
          Length = 2271

 Score =  179 bits (435), Expect = 7e-43
 Identities = 306/1507 (20%), Positives = 638/1507 (42%), Gaps = 177/1507 (11%)

Query: 143  DVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXX 202
            ++ +  N +K+  ++   L  + K +E+   DL+ ++N  +  I +K+K  +        
Sbjct: 236  ELDNAKNELKQLHSSYDNLNNEHKSLESEKEDLENELNNANSTINSKDKELSKLQRD--- 292

Query: 203  XXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEA 262
                      +  Q + K  ++         DE Q L       + ++   +  NKLL+A
Sbjct: 293  ---------NERLQNVNKENDDLKKENKSLDDEIQTLKNSNNDLNNKLQREQNQNKLLQA 343

Query: 263  ARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCE----EKTEIEEKGSLEI 318
            A   ++ +++ L  +L                  ++ I    E    ++T  +  G L  
Sbjct: 344  ANDTLTNDNNDLNDKLTSSNNDRIKAESKANTAERELINAIAEGEELKQTNKQLNGQLNE 403

Query: 319  AN---------MTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPL 369
             N         + +L KK   LE+ N +I+   +EL    A    +   ++   KK + L
Sbjct: 404  MNNNYKELQGKLNDLEKKANQLENANQRIQDLEQELAESQAESNGKDAKINELQKKANQL 463

Query: 370  -------ISRKSGRNTASK----MKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLN 418
                   + +++  +   K    +K  + QL       +   K   ++  KLE  + + N
Sbjct: 464  EPTEKKLVDKQNENDKLQKELDELKDKYDQLEKALKAAENRVKELLSQNEKLENSLDNAN 523

Query: 419  KDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEI 478
               + K   +S+++             +  +  L+ ++    +      +     ++  +
Sbjct: 524  NLSLQKGDELSKRNETLADLKKRNQELEARVRDLESQNDDEKDN----ELAAKDSEIQNL 579

Query: 479  AKVQEQLKQELND---EIK----DVNVKDL-IEKLKSAEEQITQLNDEIDAANKNMIKVK 530
                EQ K++LND   ++K    D++ KD  I+KLK   E+I +LN+++  AN  + K++
Sbjct: 580  KSQLEQTKKDLNDTQEDLKTANNDLSAKDKEIQKLKRDNEKIAKLNEDLKEANDEIKKLE 639

Query: 531  SNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDS 590
             N K  L+      D  SK+ ++ +E  R   E   L Q++ E +E+        +  + 
Sbjct: 640  -NEKDDLQSQLS--DKDSKLQNAMREKDRANNENATLKQQINECDEKLKKETGEKIKLNG 696

Query: 591  GRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKL--ADIS 648
             +    D+ +++      A+ + +A    + Q  +       LQ K ++++ K   AD  
Sbjct: 697  QK---GDLERELATANASAQQQKEATEFAQQQVQEKDARNKELQNKINDLQKKANAADNL 753

Query: 649  QLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDK-EQLYGTIKDLENDKEDIM 707
            Q Q DQ+ S +   +          ++K+  L+    K    E    ++KD + +  +  
Sbjct: 754  QQQVDQLKSMLDDANKSINDKDSQINEKQKELIETRKKASALEPTKQSLKDTQAELTEKQ 813

Query: 708  NKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENI 767
            N L N   +N +L  +L+++  ++I +L     + E + ++ Q  +D K++  D+ IE +
Sbjct: 814  NDLNNANNKNRELERELKELK-KQIGDL-----NRENNDLKEQ--LDDKVKNDDI-IEKL 864

Query: 768  ESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRL 827
              ++ +  ++I  L+    V  D   +LE K ++L       QKA  E    E++L +  
Sbjct: 865  RKQIDELNAKIQELQSQKPV--DNSSALEEKINEL-------QKAKQELEETENKLKDTT 915

Query: 828  AVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTD 887
              LM  D+ ++K    +EH + +L +  ++ L EN+                        
Sbjct: 916  DELMAKDKELQKANRGLEHLD-QLTRDLEVALAENK------------------------ 950

Query: 888  LAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLN 947
            +A++E+++ +TQL + ++ L++   ++ T +    +++     + N ++  A +D   LN
Sbjct: 951  IADAENSELKTQLANKDNELQKAKQDN-TRLQSNNEQLTANSDDLNKKLTDATKDNIKLN 1009

Query: 948  EKYEKNIEYVTQL-EAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQ 1006
             +  K++E + Q  EA+L +   ++E L   V + +    EL  K    Q+  S    E+
Sbjct: 1010 GQV-KDLERLLQSKEAELDQQNQSVEQLKSQVTDKDDKLKELQSKLNDLQKELSEK--ER 1066

Query: 1007 YINEINKLNALLKQKDEEIIALNQKIN--NAQVSYMSMVSDYESKLAQFTTKLENMEEEM 1064
              N  N L + L   D+EI + N+K+N  N     M+ V     KL     KL+  ++E+
Sbjct: 1067 LENLANSLQSKL---DDEIKSNNEKLNQLNELEKQMNEVQKKADKLQPTQDKLKYAQDEL 1123

Query: 1065 QRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKT--EGMIISSTIEPMS 1122
                K+L  S  +N +LQ  +++   Q  +L E K   E  +      G +I +  + +S
Sbjct: 1124 TEKQKELDASNANNRDLQKQIKDLKKQNDDLDEQKQKLEEQLDNNVKAGDVIGNLRKQIS 1183

Query: 1123 DD-ANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETL 1181
            +  A N D            L  +E E        L+ Q  ++  +L+E   K  +L+ +
Sbjct: 1184 ELLAKNKDLEAKNKDNNGDELAAKEAE-----LESLKNQLEQIKKDLEE---KEEELKQV 1235

Query: 1182 NTELTGHDVVNQE--QINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELW 1239
            N  L+  D   Q+  + N+  SKL++   + +N    + +  + + S +  +  E+ +  
Sbjct: 1236 NDNLSAKDKELQKLSRENEKNSKLQKDLEDANNQNKKLDDENNDLQSQLSTKDIELQK-- 1293

Query: 1240 KQHLAQREAD-FQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNK 1298
                AQ+EA   Q    +L  Q     +K ++       S  E  N  + + +  +    
Sbjct: 1294 ----AQKEAGRLQNLVQKLEEQNKDLYNKLDEETAEKLKSNGEVRNAQLELAKTKANAED 1349

Query: 1299 LQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQS 1358
            L  + EHL+    +    IN++    +E + +                        EN+ 
Sbjct: 1350 LSKENEHLQEQNNEKDSFINELRAKANEAQKKA----------------------GENE- 1386

Query: 1359 YKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQ 1418
              ++Q Q I ++N +  +L  +             ++N+A+ K  ++   L+   S+  +
Sbjct: 1387 --KLQNQ-INDLNSQIDELNNAISAQNETINDLKKKLNEAQKKANQV-EPLQQSLSDAKE 1442

Query: 1419 KTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLK-MHENANHY---- 1473
            + +E    + + N++  N  +Q  E ++R++DL  E++      RLK  ++N N+     
Sbjct: 1443 ENNEKQEKIDELNEKLRNAEKQFKEADQRVKDLLTEQQ------RLKDSYDNINNMSLQK 1496

Query: 1474 --ETMQKESEIERVK-LIEELNVKITES--VSLNKQVAELNKALEEEVAKTNEMQTALEN 1528
              E  +KE+E++ +K  +++L  K   S    + ++  EL K LE+ +   + +++ L+N
Sbjct: 1497 EDELTKKENEVDTLKKALKDLQNKTNGSNDKEIAEKEQELEKQLEDALRDLSNVKSELDN 1556

Query: 1529 QEIEIVTLNDEITNLQNMVRASSSK---IQKHVSFASDTKQGRDEQLDNTM-NKELLDAV 1584
             + E+  L+    NL N  ++  S+   ++  ++ A+ T   +D++L     + E L  V
Sbjct: 1557 AKNELKQLHSSYDNLNNEHKSLESEKEDLENELNNANSTINSKDKELSKLQRDNERLQNV 1616

Query: 1585 PRAELDL 1591
             +   DL
Sbjct: 1617 NKENDDL 1623



 Score =  175 bits (427), Expect = 6e-42
 Identities = 296/1512 (19%), Positives = 676/1512 (44%), Gaps = 137/1512 (9%)

Query: 140  QLGDVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINE-KDQIIEAKNKATTXXXX 198
            ++ D+   SN + + ++ +  L+ ++   ET+  DL  K+N+ + ++ E + KA      
Sbjct: 51   KVNDLEKKSNQLDDANSRIKELEDELTESETSKDDLSNKLNDLQKKLNELQKKANQLDQA 110

Query: 199  XXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANK 258
                          D++Q+ T+ Q+    ++ + +D ++ + K ++ K+     LE+ANK
Sbjct: 111  KKDLA---------DSQQENTEKQKEVDDLKTQLRDLEKEM-KQLQKKN---DDLEKANK 157

Query: 259  LLEAARFEISL----EHSKLAQELEQXXXXXXXXXXXXXXLAKQ----SIEPSCEEKTEI 310
             L+  + E S+    E SK  Q L                L  Q    + +    ++ EI
Sbjct: 158  DLQE-KLEDSMKQESELSKKDQVLANLKKALADATNKVKDLENQLNGSNDKDIAAKEREI 216

Query: 311  EE-KGSLEIA--NMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGS 367
            E  K  LE A  +++ +  +++  ++   Q+  +   L N+  ++ +E + + +     +
Sbjct: 217  ESLKSQLEDALRDLSNVKSELDNAKNELKQLHSSYDNLNNEHKSLESEKEDLENELNNAN 276

Query: 368  PLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDK-EY 426
              I+ K      SK++    +L +     D  KK NK+   +++  +++ N DL +K + 
Sbjct: 277  STINSKD--KELSKLQRDNERLQNVNKENDDLKKENKSLDDEIQ-TLKNSNNDLNNKLQR 333

Query: 427  VISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQE--Q 484
              ++               + L  +L   +   ++  S  +     E +N IA+ +E  Q
Sbjct: 334  EQNQNKLLQAANDTLTNDNNDLNDKLTSSNNDRIKAESKANTAER-ELINAIAEGEELKQ 392

Query: 485  LKQELNDEIKDVN--VKDLIEKLKSAEEQITQL---NDEIDAANKNMIK--VKSNHK-LK 536
              ++LN ++ ++N   K+L  KL   E++  QL   N  I    + + +   +SN K  K
Sbjct: 393  TNKQLNGQLNEMNNNYKELQGKLNDLEKKANQLENANQRIQDLEQELAESQAESNGKDAK 452

Query: 537  LKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIES 596
            + ++QK  +   ++  + K++V    E   L +++ EL+++   L+  L      +  E+
Sbjct: 453  INELQKKAN---QLEPTEKKLVDKQNENDKLQKELDELKDKYDQLEKAL------KAAEN 503

Query: 597  DVYKKMIEMENLAETRLKAISLLESQKFDLVQE----LHILQQKYDEVEDKLADISQLQS 652
             V K+++      E  L   + L  QK D + +    L  L+++  E+E ++ D+     
Sbjct: 504  RV-KELLSQNEKLENSLDNANNLSLQKGDELSKRNETLADLKKRNQELEARVRDLESQND 562

Query: 653  DQVCSEI--KSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKL 710
            D+  +E+  K   ++     L  +KK+L    E+LK     L    K+++  K D   K+
Sbjct: 563  DEKDNELAAKDSEIQNLKSQLEQTKKDLNDTQEDLKTANNDLSAKDKEIQKLKRD-NEKI 621

Query: 711  QNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESE 770
                ++  +  D+++K+  EK  +L ++++ ++ SK+Q       +    +     ++ +
Sbjct: 622  AKLNEDLKEANDEIKKLENEK-DDLQSQLS-DKDSKLQNAMREKDRANNENA---TLKQQ 676

Query: 771  LSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKA--YSEYTIQEDELVNRLA 828
            +++   ++ +       +  ++  LER+     +  Q++++A  +++  +QE +  N+  
Sbjct: 677  INECDEKLKKETGEKIKLNGQKGDLERELATANASAQQQKEATEFAQQQVQEKDARNK-- 734

Query: 829  VLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDL 888
             L +    ++K+    ++  +++ +   +L + N+++    S + +    L+E   +   
Sbjct: 735  ELQNKINDLQKKANAADNLQQQVDQLKSMLDDANKSINDKDSQINEKQKELIETRKKASA 794

Query: 889  AE--SESTK-YQTQLRDLESNLKRITHEHQTL---IVQKKKEIEDLEIEFNTQIESAIRD 942
             E   +S K  Q +L + +++L    ++++ L   + + KK+I DL  E N  ++  + D
Sbjct: 795  LEPTKQSLKDTQAELTEKQNDLNNANNKNRELERELKELKKQIGDLNRE-NNDLKEQLDD 853

Query: 943  KKVLNEKYEKNIEYVTQLEAQLQEYKNN--IENLNMNVEELNKMNLELIDKHVQKQQTQS 1000
            K   ++  EK  + + +L A++QE ++   ++N +   E++N+  L+   + +++ + + 
Sbjct: 854  KVKNDDIIEKLRKQIDELNAKIQELQSQKPVDNSSALEEKINE--LQKAKQELEETENKL 911

Query: 1001 PDYTEQYI---NEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKL 1057
             D T++ +    E+ K N  L+  D+    L + +  A     + ++D E+  ++  T+L
Sbjct: 912  KDTTDELMAKDKELQKANRGLEHLDQ----LTRDLEVALAE--NKIADAEN--SELKTQL 963

Query: 1058 ENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKE-TKLTFEMN--IPKTEGMII 1114
             N + E+Q+  +     + +NE+L       DD  K+L + TK   ++N  +   E ++ 
Sbjct: 964  ANKDNELQKAKQDNTRLQSNNEQL---TANSDDLNKKLTDATKDNIKLNGQVKDLERLLQ 1020

Query: 1115 SSTIEPMSDDANNVDXXXXXXXXXXXXLK-VQEEEEFIQERSVLQEQSAKLNTELQECYT 1173
            S   E +     +V+            LK +Q +   +Q+    +E+   L   LQ    
Sbjct: 1021 SKEAE-LDQQNQSVEQLKSQVTDKDDKLKELQSKLNDLQKELSEKERLENLANSLQSKLD 1079

Query: 1174 KIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGF 1233
               ++++ N +L   + + ++Q+N+++ K ++L    D L     EL         Q+  
Sbjct: 1080 D--EIKSNNEKLNQLNEL-EKQMNEVQKKADKLQPTQDKLKYAQDELTEK------QKEL 1130

Query: 1234 EIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDS--VQSSTQEETNKIVTMEQ 1291
            + +    + L ++  D +K   +L  Q    E + +  + +  V  + +++ ++++   +
Sbjct: 1131 DASNANNRDLQKQIKDLKKQNDDLDEQKQKLEEQLDNNVKAGDVIGNLRKQISELLAKNK 1190

Query: 1292 VTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXD 1351
                +NK  + +E L   + +   + NQ+E ++ ++E EK                    
Sbjct: 1191 DLEAKNKDNNGDE-LAAKEAELESLKNQLEQIKKDLE-EKEEELKQVNDNLSAKDKELQK 1248

Query: 1352 LRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAE---AKVLELTHQ 1408
            L  EN+   ++Q+  + + N +N +L   +             +  A+    ++  L  +
Sbjct: 1249 LSRENEKNSKLQKD-LEDANNQNKKLDDENNDLQSQLSTKDIELQKAQKEAGRLQNLVQK 1307

Query: 1409 LELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKE------SELAIL 1462
            LE ++ ++Y K  E T    + N E  N + +L + +   EDL+ E E      +E    
Sbjct: 1308 LEEQNKDLYNKLDEETAEKLKSNGEVRNAQLELAKTKANAEDLSKENEHLQEQNNEKDSF 1367

Query: 1463 RLKMHENANHYETMQKESEIERVK-LIEELNVKITE---SVSL-NKQVAELNKALEEEVA 1517
              ++   AN  E  +K  E E+++  I +LN +I E   ++S  N+ + +L K L E   
Sbjct: 1368 INELRAKAN--EAQKKAGENEKLQNQINDLNSQIDELNNAISAQNETINDLKKKLNEAQK 1425

Query: 1518 KTNE---MQTAL-----ENQEIE--IVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQG 1567
            K N+   +Q +L     EN E +  I  LN+++ N +   + +  +++  ++     K  
Sbjct: 1426 KANQVEPLQQSLSDAKEENNEKQEKIDELNEKLRNAEKQFKEADQRVKDLLTEQQRLKDS 1485

Query: 1568 RDEQLDNTMNKE 1579
             D   + ++ KE
Sbjct: 1486 YDNINNMSLQKE 1497



 Score =  173 bits (421), Expect = 3e-41
 Identities = 331/1579 (20%), Positives = 664/1579 (42%), Gaps = 160/1579 (10%)

Query: 91   SESLANTLKQKEILMEKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNT 150
            +E L N+L     L   +++  ELSKR+ T                      D     N 
Sbjct: 512  NEKLENSLDNANNL--SLQKGDELSKRNETLADLKKRNQELEARVRDLESQND-DEKDNE 568

Query: 151  IKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXX 210
            +  KD+ +  L+ +++  +  + D QE +   +  + AK+K                   
Sbjct: 569  LAAKDSEIQNLKSQLEQTKKDLNDTQEDLKTANNDLSAKDKEIQKLKRDNEKIAKLNEDL 628

Query: 211  XEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLE 270
             E    ++ K++     ++++  D+  +L   +  KD   +      + +     ++  E
Sbjct: 629  KE-ANDEIKKLENEKDDLQSQLSDKDSKLQNAMREKDRANNENATLKQQINECDEKLKKE 687

Query: 271  HSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSL--EIAN-MTELTKK 327
              +  + L                 A+Q  E +   + +++EK +   E+ N + +L KK
Sbjct: 688  TGEKIK-LNGQKGDLERELATANASAQQQKEATEFAQQQVQEKDARNKELQNKINDLQKK 746

Query: 328  IELLEHLNCQIRQ-------TNKELENKLATMGTESKAVSSPSKKGSPLI-SRKSGRNTA 379
                ++L  Q+ Q        NK + +K + +  + K +    KK S L  +++S ++T 
Sbjct: 747  ANAADNLQQQVDQLKSMLDDANKSINDKDSQINEKQKELIETRKKASALEPTKQSLKDTQ 806

Query: 380  SKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXX 439
            +++    + L+    N +   +  + E+ +L+  I  LN++  D +  + +K        
Sbjct: 807  AELTEKQNDLN----NANNKNRELERELKELKKQIGDLNRENNDLKEQLDDKVKNDDIIE 862

Query: 440  XXXXGKDTLIAQLQ-LEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQ---ELNDEIKD 495
                  D L A++Q L+ Q+ ++  S +      E +NE+ K +++L++   +L D   +
Sbjct: 863  KLRKQIDELNAKIQELQSQKPVDNSSALE-----EKINELQKAKQELEETENKLKDTTDE 917

Query: 496  VNVKDL-IEKLKSAEEQITQLNDEI----------DAAN---KNMIKVKSNHKLKLKQ-- 539
            +  KD  ++K     E + QL  ++          DA N   K  +  K N   K KQ  
Sbjct: 918  LMAKDKELQKANRGLEHLDQLTRDLEVALAENKIADAENSELKTQLANKDNELQKAKQDN 977

Query: 540  --MQKTIDNFSKVSDS-NKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYD-SGRMIE 595
              +Q   +  +  SD  NK++   T++   L+ +V +LE    + +  L   + S   ++
Sbjct: 978  TRLQSNNEQLTANSDDLNKKLTDATKDNIKLNGQVKDLERLLQSKEAELDQQNQSVEQLK 1037

Query: 596  SDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEV----EDKLADISQLQ 651
            S V  K  +++ L +++L  +    S+K  L    + LQ K D+      +KL  +++L+
Sbjct: 1038 SQVTDKDDKLKEL-QSKLNDLQKELSEKERLENLANSLQSKLDDEIKSNNEKLNQLNELE 1096

Query: 652  SDQVCSEIKSVHLEEQIDALSASKKELALVIENL---KLDKEQLYGTIKDLENDKEDI-- 706
                  + K+  L+   D L  ++ EL    + L     +   L   IKDL+   +D+  
Sbjct: 1097 KQMNEVQKKADKLQPTQDKLKYAQDELTEKQKELDASNANNRDLQKQIKDLKKQNDDLDE 1156

Query: 707  -MNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIE 765
               KL+  +  N+   D +  +  ++ISELLAK N + ++K +   G +   +E +L  E
Sbjct: 1157 QKQKLEEQLDNNVKAGDVIGNLR-KQISELLAK-NKDLEAKNKDNNGDELAAKEAEL--E 1212

Query: 766  NIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVN 825
            +++++L + K  +   EE +  + D   +L  K  +L    +E +K  S+     ++  N
Sbjct: 1213 SLKNQLEQIKKDLEEKEEELKQVND---NLSAKDKELQKLSRENEKN-SKLQKDLEDANN 1268

Query: 826  RLAVLMDHDRVVEKQL----LEIEHENKE---LQKKNQILLEENQNLQISLSDMQQHY-- 876
            +   L D +  ++ QL    +E++   KE   LQ   Q L E+N++L   L +       
Sbjct: 1269 QNKKLDDENNDLQSQLSTKDIELQKAQKEAGRLQNLVQKLEEQNKDLYNKLDEETAEKLK 1328

Query: 877  ------NALVE----KANRTDLA-ESESTKYQTQLRDLESN-LKRITHEHQTLIVQKKK- 923
                  NA +E    KAN  DL+ E+E  + Q   +D   N L+   +E Q    + +K 
Sbjct: 1329 SNGEVRNAQLELAKTKANAEDLSKENEHLQEQNNEKDSFINELRAKANEAQKKAGENEKL 1388

Query: 924  --EIEDLEI---EFNTQIES---AIRD-KKVLNEKYEKNIEYVTQLEAQLQEYKNNIENL 974
              +I DL     E N  I +    I D KK LNE  +K    V  L+  L + K      
Sbjct: 1389 QNQINDLNSQIDELNNAISAQNETINDLKKKLNEA-QKKANQVEPLQQSLSDAKEENNEK 1447

Query: 975  NMNVEELNKMNLELIDKHVQKQQTQSPDY-TEQYI--NEINKLNALLKQKDEEIIALNQK 1031
               ++ELN+  L   +K  ++   +  D  TEQ    +  + +N +  QK++E+     +
Sbjct: 1448 QEKIDELNE-KLRNAEKQFKEADQRVKDLLTEQQRLKDSYDNINNMSLQKEDELTKKENE 1506

Query: 1032 INNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQ 1091
            ++  + +    + D ++K      K   + E+ Q + KQL D+ +   +L  +  E D+ 
Sbjct: 1507 VDTLKKA----LKDLQNKTNGSNDK--EIAEKEQELEKQLEDALR---DLSNVKSELDNA 1557

Query: 1092 IKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEE--EE 1149
              ELK+   +++ N+   E   + S  E + ++ NN +            L+   E  + 
Sbjct: 1558 KNELKQLHSSYD-NL-NNEHKSLESEKEDLENELNNANSTINSKDKELSKLQRDNERLQN 1615

Query: 1150 FIQERSVLQEQSAKLNTELQ-------ECYTKIIQLETLNTELTGHDVVNQEQINQLKSK 1202
              +E   L++++  L+ E+Q       +   K+ + +  N  L   +       N L +K
Sbjct: 1616 VNKENDDLKKENKSLDDEIQTLKNSNNDLNNKLQRAQRQNELLQAANDTLTNDNNDLNNK 1675

Query: 1203 LEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLS 1262
            L ++  E  N  S        ++++++++  E  +   Q L  +  D      +L+ + +
Sbjct: 1676 LTEVTKEKINADSLAKAAERELNNSINEK--EELKASNQQLTDQLNDLMNKNKDLKKKAN 1733

Query: 1263 AFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQ---NKLQDKE-----EHLRNLQEKYA 1314
              + + + L+DS++S   E   K  T+ Q T  Q   N+L D++     + L  L +KY 
Sbjct: 1734 DAD-RLQNLVDSLKSQLAEAQKKANTVVQNTQPQPQSNELYDRQLEQLKQELEQLNDKYN 1792

Query: 1315 DVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEEN 1374
            + + +     +    EK                    +    +  +++++Q    +N  N
Sbjct: 1793 EAVQKYHDADNSARQEKQQHDLDNIKNNAAIQNKQETIENLEKQIQELEKQQNA-LNAAN 1851

Query: 1375 AQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRND-- 1432
             + +K              ++ D + K  +L  QL  K  E+ +        L + N+  
Sbjct: 1852 EEEQKQHKLDANKLQDALKKLKDEQEKNSDLEKQLIAKKDELGKANDRVKELLKENNNLK 1911

Query: 1433 -EFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEEL 1491
             E +N +     Y+  I  L  + +++L  L+     + N     +K  + + V  +E+ 
Sbjct: 1912 TEAKNNKDVSEFYQNEISMLDKDNKAKLEDLK-----DLNAKLAAEKAEKNKVVAALEQA 1966

Query: 1492 NV--KITESVS--LNKQVAELNK--------ALEEEVAK----TNEMQTALENQEIEIVT 1535
            N   K+ E  +  LNK++AEL          A ++E  K      E+Q  +   E E   
Sbjct: 1967 NAANKVLEEANNELNKELAELQSRSDSGLPLAQKQEAEKLRNRVKELQDKVRGLEAEKRQ 2026

Query: 1536 LNDEITNLQNMVRASSSKI 1554
            +ND++++LQ+ + +++S+I
Sbjct: 2027 INDDVSDLQSKLDSANSEI 2045



 Score =  169 bits (411), Expect = 5e-40
 Identities = 290/1476 (19%), Positives = 613/1476 (41%), Gaps = 132/1476 (8%)

Query: 147  LSNTIKEKDNALSVLQVKMKIMETTILDLQEKI-NEKDQIIEAKNKATTXXXXXXXXXXX 205
            L+N ++ + N   +LQ     +     DL +K+ +  +  I+A++KA T           
Sbjct: 327  LNNKLQREQNQNKLLQAANDTLTNDNNDLNDKLTSSNNDRIKAESKANTAERELINAIAE 386

Query: 206  XXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARF 265
                  E+ KQ   ++      M   +K E Q  L D+E K    + LE AN+ ++    
Sbjct: 387  G-----EELKQTNKQLNGQLNEMNNNYK-ELQGKLNDLEKK---ANQLENANQRIQ---- 433

Query: 266  EISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELT 325
                    L QEL +              L K++ +    EK  ++++   +     +L 
Sbjct: 434  -------DLEQELAESQAESNGKDAKINELQKKANQLEPTEKKLVDKQNEND-----KLQ 481

Query: 326  KKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRK----SGRN-TAS 380
            K+++ L+    Q+ +  K  EN++  + ++++ + +     + L  +K    S RN T +
Sbjct: 482  KELDELKDKYDQLEKALKAAENRVKELLSQNEKLENSLDNANNLSLQKGDELSKRNETLA 541

Query: 381  KMKSPWSQLSSETLNQDTDKKINK-NEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXX 439
             +K    +L +   + ++     K NE+A  +  IQ+L   L   +  +++         
Sbjct: 542  DLKKRNQELEARVRDLESQNDDEKDNELAAKDSEIQNLKSQLEQTKKDLNDTQEDLKTAN 601

Query: 440  XXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEI--KDVN 497
                 KD  I +L+ ++++      +  +  + ++ N+  K  E  K +L  ++  KD  
Sbjct: 602  NDLSAKDKEIQKLKRDNEK------IAKLNEDLKEANDEIKKLENEKDDLQSQLSDKDSK 655

Query: 498  VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEI 557
            +++ + +   A  +   L  +I+  ++ + K ++  K+KL   +  ++   +++ +N   
Sbjct: 656  LQNAMREKDRANNENATLKQQINECDEKL-KKETGEKIKLNGQKGDLER--ELATANASA 712

Query: 558  VRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAIS 617
             +  E      Q+V E +     LQ  + D         ++ +++ +++++ +   K+I+
Sbjct: 713  QQQKEATEFAQQQVQEKDARNKELQNKINDLQKKANAADNLQQQVDQLKSMLDDANKSIN 772

Query: 618  LLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKE 677
              +SQ  +  +EL   ++K   +E     +   Q++           E+Q D  +A+ K 
Sbjct: 773  DKDSQINEKQKELIETRKKASALEPTKQSLKDTQAELT---------EKQNDLNNANNKN 823

Query: 678  LALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLA 737
              L  E  +L K+     I DL  +  D+  +L + ++ N D+ +KL K    +I EL A
Sbjct: 824  RELERELKELKKQ-----IGDLNRENNDLKEQLDDKVK-NDDIIEKLRK----QIDELNA 873

Query: 738  KINH-EEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLE 796
            KI   + Q  +     ++ KI E    ++  + EL + ++++    + +   +       
Sbjct: 874  KIQELQSQKPVDNSSALEEKINE----LQKAKQELEETENKLKDTTDELMAKDKELQKAN 929

Query: 797  RKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQ 856
            R  + L    ++ + A +E  I + E       L + D  ++K     + +N  LQ  N+
Sbjct: 930  RGLEHLDQLTRDLEVALAENKIADAENSELKTQLANKDNELQKA----KQDNTRLQSNNE 985

Query: 857  ILLEENQNLQISLSDMQQH---YNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHE 913
             L   + +L   L+D  +     N  V+   R  L +S+  +   Q + +E    ++T +
Sbjct: 986  QLTANSDDLNKKLTDATKDNIKLNGQVKDLER--LLQSKEAELDQQNQSVEQLKSQVTDK 1043

Query: 914  HQTLIVQKKKEIEDLEIEFNTQ--IESAIRD-KKVLNEKYEKNIEYVTQL---EAQLQEY 967
               L  + + ++ DL+ E + +  +E+     +  L+++ + N E + QL   E Q+ E 
Sbjct: 1044 DDKL-KELQSKLNDLQKELSEKERLENLANSLQSKLDDEIKSNNEKLNQLNELEKQMNEV 1102

Query: 968  KNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYT-EQYINEINKLNALL---KQKDE 1023
            +   + L    ++L     EL +K  +   + + +   ++ I ++ K N  L   KQK E
Sbjct: 1103 QKKADKLQPTQDKLKYAQDELTEKQKELDASNANNRDLQKQIKDLKKQNDDLDEQKQKLE 1162

Query: 1024 EIIALNQKINNAQVSYMSMVSDYESKLAQFTTK-LENMEEEMQRVSKQLLDSKQHNEELQ 1082
            E +  N K  +   +    +S+  +K      K  +N  +E+     +L   K   E+++
Sbjct: 1163 EQLDNNVKAGDVIGNLRKQISELLAKNKDLEAKNKDNNGDELAAKEAELESLKNQLEQIK 1222

Query: 1083 ILVREQDDQIKELKETKLTFEMNIPK-TEGMIISSTIEPMSDDANNVDXXXXXXXX---X 1138
              + E+++++K++ +     +  + K +     +S ++   +DANN +            
Sbjct: 1223 KDLEEKEEELKQVNDNLSAKDKELQKLSRENEKNSKLQKDLEDANNQNKKLDDENNDLQS 1282

Query: 1139 XXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVN-QEQIN 1197
                K  E ++  +E   LQ    KL  + ++ Y K+ + ET     +  +V N Q ++ 
Sbjct: 1283 QLSTKDIELQKAQKEAGRLQNLVQKLEEQNKDLYNKLDE-ETAEKLKSNGEVRNAQLELA 1341

Query: 1198 QLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHEL 1257
            + K+  E L+ EN++L     E  +   S +++   +  E  K+  A      Q   ++L
Sbjct: 1342 KTKANAEDLSKENEHL----QEQNNEKDSFINELRAKANEAQKK--AGENEKLQNQINDL 1395

Query: 1258 RVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVI 1317
              Q+    +      +++    ++         QV  LQ  L D +E     QEK  D +
Sbjct: 1396 NSQIDELNNAISAQNETINDLKKKLNEAQKKANQVEPLQQSLSDAKEENNEKQEKI-DEL 1454

Query: 1318 NQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQL 1377
            N  E LR+  +  K A                 DL TE Q  K   +    NIN  + Q 
Sbjct: 1455 N--EKLRNAEKQFKEA------------DQRVKDLLTEQQRLKDSYD----NINNMSLQK 1496

Query: 1378 KKSSXXXXXXXXXXXXRVNDAEAKVLELTH-QLELKDSEIYQKTHEYTITLTQRNDEFEN 1436
            +                + D + K       ++  K+ E+ ++  +    L+    E +N
Sbjct: 1497 EDELTKKENEVDTLKKALKDLQNKTNGSNDKEIAEKEQELEKQLEDALRDLSNVKSELDN 1556

Query: 1437 VRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKIT 1496
             + +L +     ++L  E +S L   +  +    N+  +     + E  KL  + N ++ 
Sbjct: 1557 AKNELKQLHSSYDNLNNEHKS-LESEKEDLENELNNANSTINSKDKELSKLQRD-NERLQ 1614

Query: 1497 ESVSLNKQVAELNKALEEEVAK--------TNEMQTALENQEIEIVTLNDEITNLQNMVR 1548
                 N  + + NK+L++E+           N++Q A    E+ +   ND +TN  N + 
Sbjct: 1615 NVNKENDDLKKENKSLDDEIQTLKNSNNDLNNKLQRAQRQNEL-LQAANDTLTNDNNDLN 1673

Query: 1549 ASSSKIQKHVSFASDTKQGRDEQLDNTMN-KELLDA 1583
               +++ K    A    +  + +L+N++N KE L A
Sbjct: 1674 NKLTEVTKEKINADSLAKAAERELNNSINEKEELKA 1709



 Score =  162 bits (393), Expect = 8e-38
 Identities = 225/1047 (21%), Positives = 458/1047 (43%), Gaps = 83/1047 (7%)

Query: 570  KVAELEEEKGNLQLHLVDYDSGRMIE------SDVYKKMIEMENLAETRLKAIS--LLES 621
            K A  E  K N QL  ++ D    I+      +D+ KK  ++++ A +R+K +   L ES
Sbjct: 21   KAASEELAKTNEQLDNLNKDKDNKIKELQSKVNDLEKKSNQLDD-ANSRIKELEDELTES 79

Query: 622  Q--KFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELA 679
            +  K DL  +L+ LQ+K +E++ K   + Q + D   S+ ++   ++++D L    ++L 
Sbjct: 80   ETSKDDLSNKLNDLQKKLNELQKKANQLDQAKKDLADSQQENTEKQKEVDDLKTQLRDLE 139

Query: 680  LVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAE---KISELL 736
              ++ L+   + L    KDL+   ED M K ++ + +   +   L+K  A+   K+ +L 
Sbjct: 140  KEMKQLQKKNDDLEKANKDLQEKLEDSM-KQESELSKKDQVLANLKKALADATNKVKDLE 198

Query: 737  AKINHEEQSKIQTQ----FGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRR 792
             ++N      I  +      + +++++    + N++SEL   K+ + +L  S   + +  
Sbjct: 199  NQLNGSNDKDIAAKEREIESLKSQLEDALRDLSNVKSELDNAKNELKQLHSSYDNLNNEH 258

Query: 793  YSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRV--VEKQLLEIEHENKE 850
             SLE + + L +   E   A S    ++ EL     +  D++R+  V K+  +++ ENK 
Sbjct: 259  KSLESEKEDLEN---ELNNANSTINSKDKELSK---LQRDNERLQNVNKENDDLKKENKS 312

Query: 851  LQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESE--STKYQTQLRD-LESNL 907
            L  + Q L   N +L   L   +Q+ N L++ AN T   ++   + K  +   D +++  
Sbjct: 313  LDDEIQTLKNSNNDLNNKL-QREQNQNKLLQAANDTLTNDNNDLNDKLTSSNNDRIKAES 371

Query: 908  KRITHEHQTL-IVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQE 966
            K  T E + +  + + +E++    + N Q+     + K L  K     +   QLE   Q 
Sbjct: 372  KANTAERELINAIAEGEELKQTNKQLNGQLNEMNNNYKELQGKLNDLEKKANQLENANQR 431

Query: 967  YKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDE--- 1023
             ++  + L  +  E N  + ++    +QK+  Q     ++ +++ N+ + L K+ DE   
Sbjct: 432  IQDLEQELAESQAESNGKDAKI--NELQKKANQLEPTEKKLVDKQNENDKLQKELDELKD 489

Query: 1024 EIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENME----EEMQRVSKQLLDSKQHNE 1079
            +   L + +  A+     ++S  E KL        N+     +E+ + ++ L D K+ N+
Sbjct: 490  KYDQLEKALKAAENRVKELLSQNE-KLENSLDNANNLSLQKGDELSKRNETLADLKKRNQ 548

Query: 1080 ELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXX 1139
            EL+  VR+ + Q  + K+ +L  +     +E   + S +E    D N+            
Sbjct: 549  ELEARVRDLESQNDDEKDNELAAK----DSEIQNLKSQLEQTKKDLNDTQ---EDLKTAN 601

Query: 1140 XXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQL 1199
              L  +++E  IQ+     E+ AKLN +L+E   +I +LE    +L       Q Q++  
Sbjct: 602  NDLSAKDKE--IQKLKRDNEKIAKLNEDLKEANDEIKKLENEKDDL-------QSQLSDK 652

Query: 1200 KSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQH--LAQREADFQKTEHEL 1257
             SKL+    E D   +  A L+  I+   ++   E  E  K +      E +        
Sbjct: 653  DSKLQNAMREKDRANNENATLKQQINECDEKLKKETGEKIKLNGQKGDLERELATANASA 712

Query: 1258 RVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVI 1317
            + Q  A E   +Q+ +   +  +E  NKI  +++  +  + LQ + + L+++ +     I
Sbjct: 713  QQQKEATEFAQQQVQEK-DARNKELQNKINDLQKKANAADNLQQQVDQLKSMLDDANKSI 771

Query: 1318 N----QIEILRSE-IEDEKVAFX-----XXXXXXXXXXXXXXXDLRTENQSYKQMQEQSI 1367
            N    QI   + E IE  K A                      DL   N   +++ E+ +
Sbjct: 772  NDKDSQINEKQKELIETRKKASALEPTKQSLKDTQAELTEKQNDLNNANNKNREL-EREL 830

Query: 1368 LNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIY-QKTHEYTIT 1426
              + ++   L + +            + +D   K+ +   +L  K  E+  QK  + +  
Sbjct: 831  KELKKQIGDLNREN-NDLKEQLDDKVKNDDIIEKLRKQIDELNAKIQELQSQKPVDNSSA 889

Query: 1427 LTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVK 1486
            L ++ +E +  +Q+L E E +++D T E  ++   L+ K +    H + + ++ E+    
Sbjct: 890  LEEKINELQKAKQELEETENKLKDTTDELMAKDKELQ-KANRGLEHLDQLTRDLEV---- 944

Query: 1487 LIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNM 1546
             + E  +   E+  L  Q+A  NK  + E+ K  +  T L++   ++   +D++      
Sbjct: 945  ALAENKIADAENSELKTQLA--NK--DNELQKAKQDNTRLQSNNEQLTANSDDLNKKLTD 1000

Query: 1547 VRASSSKIQKHVSFASDTKQGRDEQLD 1573
                + K+   V       Q ++ +LD
Sbjct: 1001 ATKDNIKLNGQVKDLERLLQSKEAELD 1027



 Score =  154 bits (373), Expect = 2e-35
 Identities = 248/1136 (21%), Positives = 490/1136 (43%), Gaps = 123/1136 (10%)

Query: 502  IEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVS----DSNKEI 557
            ++  K+A E++ + N+++D  NK+    K N   K+K++Q  +++  K S    D+N  I
Sbjct: 17   LQTAKAASEELAKTNEQLDNLNKD----KDN---KIKELQSKVNDLEKKSNQLDDANSRI 69

Query: 558  VRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAIS 617
              L +EL        +L  +  +LQ  L +            K + + +     + K + 
Sbjct: 70   KELEDELTESETSKDDLSNKLNDLQKKLNELQKKANQLDQAKKDLADSQQENTEKQKEVD 129

Query: 618  LLESQKFDLVQELHILQQKYDEVE-------DKLADISQLQS-----DQVCSEIKSV--- 662
             L++Q  DL +E+  LQ+K D++E       +KL D  + +S     DQV + +K     
Sbjct: 130  DLKTQLRDLEKEMKQLQKKNDDLEKANKDLQEKLEDSMKQESELSKKDQVLANLKKALAD 189

Query: 663  ------HLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQE 716
                   LE Q++   ++ K++A     ++  K QL   ++DL N K ++ N  +N +++
Sbjct: 190  ATNKVKDLENQLN--GSNDKDIAAKEREIESLKSQLEDALRDLSNVKSELDN-AKNELKQ 246

Query: 717  NMDLTDKL--EKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKY 774
                 D L  E  S E   E L    +   S I ++    +K+Q  +  ++N+  E    
Sbjct: 247  LHSSYDNLNNEHKSLESEKEDLENELNNANSTINSKDKELSKLQRDNERLQNVNKENDDL 306

Query: 775  KSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHD 834
            K     L++ I  +++    L  K  +  +  +  Q A    T   ++L ++L    ++D
Sbjct: 307  KKENKSLDDEIQTLKNSNNDLNNKLQREQNQNKLLQAANDTLTNDNNDLNDKL-TSSNND 365

Query: 835  RV--------VEKQLLEIEHENKELQKKNQIL---LEENQN----LQISLSDMQQHYNAL 879
            R+         E++L+    E +EL++ N+ L   L E  N    LQ  L+D+++  N L
Sbjct: 366  RIKAESKANTAERELINAIAEGEELKQTNKQLNGQLNEMNNNYKELQGKLNDLEKKANQL 425

Query: 880  VEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIE-S 938
                 R    E E  + Q +    ++ +  +  +   L   +KK ++        Q E  
Sbjct: 426  ENANQRIQDLEQELAESQAESNGKDAKINELQKKANQLEPTEKKLVDKQNENDKLQKELD 485

Query: 939  AIRDKKVLNEKYEKNIE-YVTQLEAQLQEYKNNIENLN----MNVEELNKMNLELIDKHV 993
             ++DK    EK  K  E  V +L +Q ++ +N+++N N       +EL+K N  L D   
Sbjct: 486  ELKDKYDQLEKALKAAENRVKELLSQNEKLENSLDNANNLSLQKGDELSKRNETLADLKK 545

Query: 994  QKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQF 1053
            + Q+ ++     +  N+  K N  L  KD EI  L  ++   +      ++D +  L   
Sbjct: 546  RNQELEARVRDLESQNDDEKDNE-LAAKDSEIQNLKSQLEQTKKD----LNDTQEDLKTA 600

Query: 1054 TTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMI 1113
               L   ++E+Q++ +      + NE+L    +E +D+IK+L+  K   +  +   +  +
Sbjct: 601  NNDLSAKDKEIQKLKRDNEKIAKLNEDL----KEANDEIKKLENEKDDLQSQLSDKDSKL 656

Query: 1114 ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYT 1173
             ++  E   D ANN +               +E  E I+      +   +L T       
Sbjct: 657  QNAMRE--KDRANNENATLKQQINECDEKLKKETGEKIKLNGQKGDLERELATANASAQQ 714

Query: 1174 KIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGF 1233
            +    E    ++   D  N+E  N++    ++ N   DNL   V +L+S +  A      
Sbjct: 715  QKEATEFAQQQVQEKDARNKELQNKINDLQKKANAA-DNLQQQVDQLKSMLDDANKSIND 773

Query: 1234 EIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVT 1293
            + +++ ++         QK   E R + SA E   + L D+ Q+   E+ N       + 
Sbjct: 774  KDSQINEK---------QKELIETRKKASALEPTKQSLKDT-QAELTEKQN------DLN 817

Query: 1294 SLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLR 1353
            +  NK ++ E  L+ L+++  D+  +   L+ ++ D+KV                   ++
Sbjct: 818  NANNKNRELERELKELKKQIGDLNRENNDLKEQL-DDKVKNDDIIEKLRKQIDELNAKIQ 876

Query: 1354 TENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKD 1413
             E QS K +   S L   E+  +L+K+              + + E K+ + T +L  KD
Sbjct: 877  -ELQSQKPVDNSSAL--EEKINELQKAK-----------QELEETENKLKDTTDELMAKD 922

Query: 1414 SEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDL-TYEKESELAILRLKMHENANH 1472
             E+ QK +     L Q   + E     +   E +I D    E +++LA    ++ +    
Sbjct: 923  KEL-QKANRGLEHLDQLTRDLE-----VALAENKIADAENSELKTQLANKDNELQKAKQD 976

Query: 1473 YETMQKESEIERVKLIEELNVKIT----ESVSLNKQVAELNKALEEEVAKTNEMQTALEN 1528
               +Q  +E +     ++LN K+T    +++ LN QV +L + L+ + A+ ++   ++E 
Sbjct: 977  NTRLQSNNE-QLTANSDDLNKKLTDATKDNIKLNGQVKDLERLLQSKEAELDQQNQSVEQ 1035

Query: 1529 QEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAV 1584
             + ++   +D++  LQ+ +    + +QK +S     ++ R E L N++  +L D +
Sbjct: 1036 LKSQVTDKDDKLKELQSKL----NDLQKELS-----EKERLENLANSLQSKLDDEI 1082



 Score =  154 bits (373), Expect = 2e-35
 Identities = 267/1327 (20%), Positives = 558/1327 (42%), Gaps = 105/1327 (7%)

Query: 323  ELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKM 382
            EL K  E L++LN       KEL++K+  +  +S  +   + +   L    +   T+   
Sbjct: 26   ELAKTNEQLDNLNKDKDNKIKELQSKVNDLEKKSNQLDDANSRIKELEDELTESETSK-- 83

Query: 383  KSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXX 442
                  LS++ LN D  KK+  NE+ K    +    KDL D +   +EK           
Sbjct: 84   ----DDLSNK-LN-DLQKKL--NELQKKANQLDQAKKDLADSQQENTEKQKEVDDLKTQL 135

Query: 443  XGKDTLIAQLQLEHQQHMEGPSLIH--VGTNTEDVNEIAKVQEQLKQELNDEIKDV--NV 498
               +  + QLQ ++    +    +   +  + +  +E++K ++Q+   L   + D    V
Sbjct: 136  RDLEKEMKQLQKKNDDLEKANKDLQEKLEDSMKQESELSK-KDQVLANLKKALADATNKV 194

Query: 499  KDLIEKLKSA--------EEQITQLNDEIDAANKNMIKVKS---NHKLKLKQMQKTIDNF 547
            KDL  +L  +        E +I  L  +++ A +++  VKS   N K +LKQ+  + DN 
Sbjct: 195  KDLENQLNGSNDKDIAAKEREIESLKSQLEDALRDLSNVKSELDNAKNELKQLHSSYDNL 254

Query: 548  SKVSDS-NKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEME 606
            +    S   E   L  EL++ +  +   ++E   LQ       +      D+ K+   ++
Sbjct: 255  NNEHKSLESEKEDLENELNNANSTINSKDKELSKLQRDNERLQNVNKENDDLKKENKSLD 314

Query: 607  NLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLAD----ISQLQSDQVCSEIKSV 662
            +  +T   + + L ++      +  +LQ   D + +   D    ++   +D++ +E K+ 
Sbjct: 315  DEIQTLKNSNNDLNNKLQREQNQNKLLQAANDTLTNDNNDLNDKLTSSNNDRIKAESKAN 374

Query: 663  HLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLE---NDKEDIMNKLQNYIQENMD 719
              E ++    A  +EL    + L     ++    K+L+   ND E   N+L+N  Q   D
Sbjct: 375  TAERELINAIAEGEELKQTNKQLNGQLNEMNNNYKELQGKLNDLEKKANQLENANQRIQD 434

Query: 720  LTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRIC 779
            L  +L +  AE   +  AKIN E Q K       + K+ ++    + ++ EL + K +  
Sbjct: 435  LEQELAESQAESNGK-DAKIN-ELQKKANQLEPTEKKLVDKQNENDKLQKELDELKDKYD 492

Query: 780  RLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEK 839
            +LE+++   E+R   L  + ++L + L        +   +  +    LA L   ++ +E 
Sbjct: 493  QLEKALKAAENRVKELLSQNEKLENSLDNANNLSLQKGDELSKRNETLADLKKRNQELEA 552

Query: 840  QLLEIEHENKELQKKNQILLEEN--QNLQISLSDMQQHYNALVE--KANRTDLAESESTK 895
            ++ ++E +N + +K N++  +++  QNL+  L   ++  N   E  K    DL+ ++  +
Sbjct: 553  RVRDLESQNDD-EKDNELAAKDSEIQNLKSQLEQTKKDLNDTQEDLKTANNDLS-AKDKE 610

Query: 896  YQTQLRDLE--SNLKRITHEHQTLIVQKKKEIEDLEIEF---NTQIESAIRDKKVLNEKY 950
             Q   RD E  + L     E    I + + E +DL+ +    ++++++A+R+K   N + 
Sbjct: 611  IQKLKRDNEKIAKLNEDLKEANDEIKKLENEKDDLQSQLSDKDSKLQNAMREKDRANNEN 670

Query: 951  EKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQ-KQQTQSPDYTEQYIN 1009
                + + + + +L+  K   E + +N ++   +  EL   +   +QQ ++ ++ +Q + 
Sbjct: 671  ATLKQQINECDEKLK--KETGEKIKLNGQK-GDLERELATANASAQQQKEATEFAQQQVQ 727

Query: 1010 EINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSK 1069
            E +  N  L+ K  ++    QK  NA  +    V   +S L      + + + ++    K
Sbjct: 728  EKDARNKELQNKINDL----QKKANAADNLQQQVDQLKSMLDDANKSINDKDSQINEKQK 783

Query: 1070 QLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVD 1129
            +L+++++    L+   +   D   EL E +   ++N    +   +   ++ +     +++
Sbjct: 784  ELIETRKKASALEPTKQSLKDTQAELTEKQ--NDLNNANNKNRELERELKELKKQIGDLN 841

Query: 1130 XXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKL-NTELQECYTKIIQLETLNTELTGH 1188
                         KV+ ++   + R  + E +AK+   + Q+       LE    EL   
Sbjct: 842  RENNDLKEQLDD-KVKNDDIIEKLRKQIDELNAKIQELQSQKPVDNSSALEEKINELQKA 900

Query: 1189 DVVNQEQINQLKSKLEQLNTENDNL------LSTVAELRSSISSAVDQRGFEIAE--LWK 1240
                +E  N+LK   ++L  ++  L      L  + +L   +  A+ +     AE    K
Sbjct: 901  KQELEETENKLKDTTDELMAKDKELQKANRGLEHLDQLTRDLEVALAENKIADAENSELK 960

Query: 1241 QHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTME-QVTSLQNKL 1299
              LA ++ + QK + +   +L +   +     D +     + T   + +  QV  L+  L
Sbjct: 961  TQLANKDNELQKAKQD-NTRLQSNNEQLTANSDDLNKKLTDATKDNIKLNGQVKDLERLL 1019

Query: 1300 QDKEEHL-------RNLQEKYADVINQIEILRSEIED---EKVAFXXXXXXXXXXXXXXX 1349
            Q KE  L         L+ +  D  ++++ L+S++ D   E                   
Sbjct: 1020 QSKEAELDQQNQSVEQLKSQVTDKDDKLKELQSKLNDLQKELSEKERLENLANSLQSKLD 1079

Query: 1350 XDLRTENQSYKQMQ--EQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEA-KVLELT 1406
             ++++ N+   Q+   E+ +  + ++  +L+ +             +  + +A       
Sbjct: 1080 DEIKSNNEKLNQLNELEKQMNEVQKKADKLQPTQDKLKYAQDELTEKQKELDASNANNRD 1139

Query: 1407 HQLELKD--------SEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKE-- 1456
             Q ++KD         E  QK  E      +  D   N+R+Q+ E   + +DL  + +  
Sbjct: 1140 LQKQIKDLKKQNDDLDEQKQKLEEQLDNNVKAGDVIGNLRKQISELLAKNKDLEAKNKDN 1199

Query: 1457 --SELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEE 1514
               ELA    ++    N  E ++K+ E E+ + ++++N       +L+ +  EL K L  
Sbjct: 1200 NGDELAAKEAELESLKNQLEQIKKDLE-EKEEELKQVN------DNLSAKDKELQK-LSR 1251

Query: 1515 EVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASS---SKIQKHVSFASDTKQGRDEQ 1571
            E  K +++Q  LE+   +   L+DE  +LQ+ +        K QK      +  Q  +EQ
Sbjct: 1252 ENEKNSKLQKDLEDANNQNKKLDDENNDLQSQLSTKDIELQKAQKEAGRLQNLVQKLEEQ 1311

Query: 1572 LDNTMNK 1578
              +  NK
Sbjct: 1312 NKDLYNK 1318



 Score =  147 bits (357), Expect = 2e-33
 Identities = 295/1455 (20%), Positives = 597/1455 (41%), Gaps = 169/1455 (11%)

Query: 56   RAQKCLENAALVSKRIKEHRKATAELLGRPFVPGISESLANTLKQKEILMEKIKQYKELS 115
            ++QK ++N++ + ++I E +KA  EL          E   N LK  +   E + + KEL 
Sbjct: 879  QSQKPVDNSSALEEKINELQKAKQEL----------EETENKLK--DTTDELMAKDKELQ 926

Query: 116  KRSSTTIVRXXXXXXXXXXXXXXXQLGDV--THLSNTIKEKDNALSV-------LQVKMK 166
            K ++  +                 ++ D   + L   +  KDN L         LQ   +
Sbjct: 927  K-ANRGLEHLDQLTRDLEVALAENKIADAENSELKTQLANKDNELQKAKQDNTRLQSNNE 985

Query: 167  IMETTILDLQEKINE--KDQI-IEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQE 223
             +     DL +K+ +  KD I +  + K                    E  K Q+T   +
Sbjct: 986  QLTANSDDLNKKLTDATKDNIKLNGQVKDLERLLQSKEAELDQQNQSVEQLKSQVTDKDD 1045

Query: 224  NFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQ--ELEQX 281
                ++++  D    L K++  K+ R+ +L  AN L      EI   + KL Q  ELE+ 
Sbjct: 1046 KLKELQSKLND----LQKELSEKE-RLENL--ANSLQSKLDDEIKSNNEKLNQLNELEKQ 1098

Query: 282  XXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQT 341
                           +  ++ + +E TE +++     AN  +L K+I+ L+  N  + + 
Sbjct: 1099 MNEVQKKADKLQP-TQDKLKYAQDELTEKQKELDASNANNRDLQKQIKDLKKQNDDLDEQ 1157

Query: 342  NKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKK 401
             ++LE +L         + +  K+ S L+++                   E  N+D    
Sbjct: 1158 KQKLEEQLDNNVKAGDVIGNLRKQISELLAKNK---------------DLEAKNKDN--- 1199

Query: 402  INKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHME 461
             N +E+A  E  ++SL   L   +  + EK+            KD  + +L  E++++ +
Sbjct: 1200 -NGDELAAKEAELESLKNQLEQIKKDLEEKEEELKQVNDNLSAKDKELQKLSRENEKNSK 1258

Query: 462  GPSLIHVGTNT----EDVNEIAKVQEQLKQ-ELNDEIKDVN-VKDLIEKLKSAEEQITQL 515
                +    N     +D N   + Q   K  EL    K+   +++L++KL   EEQ   L
Sbjct: 1259 LQKDLEDANNQNKKLDDENNDLQSQLSTKDIELQKAQKEAGRLQNLVQKL---EEQNKDL 1315

Query: 516  NDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELE 575
             +++D       K+KSN +++  Q++      +   D +KE   L E+ +     + EL 
Sbjct: 1316 YNKLDEETAE--KLKSNGEVRNAQLELAKTK-ANAEDLSKENEHLQEQNNEKDSFINELR 1372

Query: 576  EEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQ 635
             +    Q    + +  +   +D+  ++ E+ N    + + I+       DL ++L+  Q+
Sbjct: 1373 AKANEAQKKAGENEKLQNQINDLNSQIDELNNAISAQNETIN-------DLKKKLNEAQK 1425

Query: 636  KYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQL--- 692
            K ++VE     +S  + +    + K   L E++       KE    +++L  ++++L   
Sbjct: 1426 KANQVEPLQQSLSDAKEENNEKQEKIDELNEKLRNAEKQFKEADQRVKDLLTEQQRLKDS 1485

Query: 693  YGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKI-QTQF 751
            Y  I ++   KED + K +N +       D L+K     + +L  K N     +I + + 
Sbjct: 1486 YDNINNMSLQKEDELTKKENEV-------DTLKKA----LKDLQNKTNGSNDKEIAEKEQ 1534

Query: 752  GIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQK 811
             ++ ++++    + N++SEL   K+ + +L  S   + +   SLE + + L + L     
Sbjct: 1535 ELEKQLEDALRDLSNVKSELDNAKNELKQLHSSYDNLNNEHKSLESEKEDLENELNNANS 1594

Query: 812  AYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSD 871
              +     +D+ +++L    D++R     L  +  EN +L+K+N+ L +E Q L+ S +D
Sbjct: 1595 TINS----KDKELSKLQ--RDNER-----LQNVNKENDDLKKENKSLDDEIQTLKNSNND 1643

Query: 872  MQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIE 931
            +    N L     + +L ++ +        DL + L  +T E     +      +  E E
Sbjct: 1644 LN---NKLQRAQRQNELLQAANDTLTNDNNDLNNKLTEVTKEK----INADSLAKAAERE 1696

Query: 932  FNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDK 991
             N  I     + K  N++    +  +      L++  N+ + L   V+ L     E   K
Sbjct: 1697 LNNSINEK-EELKASNQQLTDQLNDLMNKNKDLKKKANDADRLQNLVDSLKSQLAEAQKK 1755

Query: 992  -HVQKQQTQ-SPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESK 1049
             +   Q TQ  P   E Y  ++ +L   L+Q       LN K N A   Y          
Sbjct: 1756 ANTVVQNTQPQPQSNELYDRQLEQLKQELEQ-------LNDKYNEAVQKYHD-------- 1800

Query: 1050 LAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKT 1109
             A  + + E  + ++  +      + Q+ +E    +   + QI+EL++ +    +N    
Sbjct: 1801 -ADNSARQEKQQHDLDNIKNNA--AIQNKQET---IENLEKQIQELEKQQNA--LNAANE 1852

Query: 1110 EGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQ 1169
            E        +    DAN +              K+++E+E   + S L++Q      EL 
Sbjct: 1853 EEQ------KQHKLDANKLQDALK---------KLKDEQE---KNSDLEKQLIAKKDELG 1894

Query: 1170 ECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVD 1229
            +   ++ +L   N  L      N++     ++++  L+ +N   L  + +L + +++   
Sbjct: 1895 KANDRVKELLKENNNLKTEAKNNKDVSEFYQNEISMLDKDNKAKLEDLKDLNAKLAAEKA 1954

Query: 1230 QRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTM 1289
            ++   +A L + + A +    ++  +EL  +L+  +S+ +  L   Q   ++E  K+   
Sbjct: 1955 EKNKVVAALEQANAANKV--LEEANNELNKELAELQSRSDSGLPLAQ---KQEAEKL--R 2007

Query: 1290 EQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXX 1349
             +V  LQ+K++  E   R + +  +D+ ++++   SEI D K                  
Sbjct: 2008 NRVKELQDKVRGLEAEKRQINDDVSDLQSKLDSANSEIADLKQKLAAAQSALGEQQKKAE 2067

Query: 1350 XDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQL 1409
              L+  N++ ++ Q+     I  +N+   K+             ++ND E K  E    L
Sbjct: 2068 DLLQKLNKAEQENQQ-----IQAQNSNESKNISDLAEKLKNLQKKLND-EMKEKE---AL 2118

Query: 1410 ELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYE---KESELAILRLKM 1466
            + K S   ++  +    L Q+ +E ++++ QL E EK + DL  +   K  E+  L+ ++
Sbjct: 2119 KSKLSAAEKEVSDLKSKLQQQTEENKDLKAQLAESEKNVNDLQSKLQAKNKEMDDLKQQL 2178

Query: 1467 HENANHYETMQKESE 1481
             + A      QK+ E
Sbjct: 2179 SDAAQEVIAAQKKLE 2193



 Score =  147 bits (357), Expect = 2e-33
 Identities = 254/1237 (20%), Positives = 520/1237 (42%), Gaps = 126/1237 (10%)

Query: 144  VTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXX 203
            V  L + + +KD+ L  LQ K+        DLQ++++EK+++    N   +         
Sbjct: 1033 VEQLKSQVTDKDDKLKELQSKLN-------DLQKELSEKERLENLANSLQSKLDDEIKSN 1085

Query: 204  XXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAA 263
                    E  ++QM ++Q+    ++   +D+ +    ++  K   + +    N+ L+  
Sbjct: 1086 NEKLNQLNE-LEKQMNEVQKKADKLQPT-QDKLKYAQDELTEKQKELDASNANNRDLQKQ 1143

Query: 264  RFEISLEHSKL---AQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIAN 320
              ++  ++  L    Q+LE+              L KQ  E   + K ++E K      N
Sbjct: 1144 IKDLKKQNDDLDEQKQKLEEQLDNNVKAGDVIGNLRKQISELLAKNK-DLEAKNKDN--N 1200

Query: 321  MTELTKKIELLEHLNCQIRQTNKELENK----------LATMGTESKAVSSPSKKGSPLI 370
              EL  K   LE L  Q+ Q  K+LE K          L+    E + +S  ++K S L 
Sbjct: 1201 GDELAAKEAELESLKNQLEQIKKDLEEKEEELKQVNDNLSAKDKELQKLSRENEKNSKLQ 1260

Query: 371  SR-KSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSL---NKDLVDKEY 426
               +   N   K+    + L S+   +D + +  + E  +L+ ++Q L   NKDL +K  
Sbjct: 1261 KDLEDANNQNKKLDDENNDLQSQLSTKDIELQKAQKEAGRLQNLVQKLEEQNKDLYNK-- 1318

Query: 427  VISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTED--VNEI-AKVQE 483
             + E+                 +A+ +   +   +    +    N +D  +NE+ AK  E
Sbjct: 1319 -LDEETAEKLKSNGEVRNAQLELAKTKANAEDLSKENEHLQEQNNEKDSFINELRAKANE 1377

Query: 484  QLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKT 543
              K+   +E     + DL         QI +LN+ I A N+ +  +K       K+  + 
Sbjct: 1378 AQKKAGENEKLQNQINDL-------NSQIDELNNAISAQNETINDLKKKLNEAQKKANQV 1430

Query: 544  IDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMI 603
                  +SD+ +E     E++  L++K+   E++       + D  + +    D Y  + 
Sbjct: 1431 EPLQQSLSDAKEENNEKQEKIDELNEKLRNAEKQFKEADQRVKDLLTEQQRLKDSYDNIN 1490

Query: 604  EMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDK-LADISQLQSDQVCSEIKSV 662
             M    E  L   +  E++   L + L  LQ K +   DK +A+  Q    Q+   ++ +
Sbjct: 1491 NMSLQKEDEL---TKKENEVDTLKKALKDLQNKTNGSNDKEIAEKEQELEKQLEDALRDL 1547

Query: 663  -HLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLT 721
             +++ ++D      K+L    +NL  +        K LE++KED+ N+L N     ++  
Sbjct: 1548 SNVKSELDNAKNELKQLHSSYDNLNNEH-------KSLESEKEDLENELNN-ANSTINSK 1599

Query: 722  DKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRL 781
            DK E    ++ +E L  +N E     +    +D +IQ     ++N  ++L+    R  R 
Sbjct: 1600 DK-ELSKLQRDNERLQNVNKENDDLKKENKSLDDEIQT----LKNSNNDLNNKLQRAQRQ 1654

Query: 782  EESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQL 841
             E +    D   +L    + L + L E  K      I  D L           +  E++L
Sbjct: 1655 NELLQAAND---TLTNDNNDLNNKLTEVTKE----KINADSLA----------KAAEREL 1697

Query: 842  LEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLR 901
                +E +EL+  NQ L +        L+D+      L +KAN  D       + Q  + 
Sbjct: 1698 NNSINEKEELKASNQQLTD-------QLNDLMNKNKDLKKKANDAD-------RLQNLVD 1743

Query: 902  DLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIE--YVTQ 959
             L+S L     +  T++   + + +  E+ ++ Q+E   ++ + LN+KY + ++  +   
Sbjct: 1744 SLKSQLAEAQKKANTVVQNTQPQPQSNEL-YDRQLEQLKQELEQLNDKYNEAVQKYHDAD 1802

Query: 960  LEAQLQEYKNNIENLNMNVEELNKM-NLELIDKHVQ---KQQ----TQSPDYTEQYINEI 1011
              A+ ++ +++++N+  N    NK   +E ++K +Q   KQQ      + +  +Q+  + 
Sbjct: 1803 NSARQEKQQHDLDNIKNNAAIQNKQETIENLEKQIQELEKQQNALNAANEEEQKQHKLDA 1862

Query: 1012 NKL-NALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQ 1070
            NKL +AL K KDE+    N  +    ++    +     ++ +   +  N++ E +  +K 
Sbjct: 1863 NKLQDALKKLKDEQ--EKNSDLEKQLIAKKDELGKANDRVKELLKENNNLKTEAKN-NKD 1919

Query: 1071 LLDSKQHNEELQILVREQDDQIKELKE--TKLTFE------MNIPKTEGMIISSTIEPMS 1122
            +  S+ +  E+ +L ++   ++++LK+   KL  E      +     +    +  +E  +
Sbjct: 1920 V--SEFYQNEISMLDKDNKAKLEDLKDLNAKLAAEKAEKNKVVAALEQANAANKVLEEAN 1977

Query: 1123 DDANNVDXXXXXXXXXXXXLKVQEEEEFIQER-SVLQEQSAKLNTELQECYTKIIQLETL 1181
            ++ N               L  ++E E ++ R   LQ++   L  E ++    +  L++ 
Sbjct: 1978 NELNKELAELQSRSDSGLPLAQKQEAEKLRNRVKELQDKVRGLEAEKRQINDDVSDLQSK 2037

Query: 1182 NTELTGHDVVNQEQINQLKSKL-EQLNTENDNL--LSTVAELRSSISSAVDQRGFEIAEL 1238
                       ++++   +S L EQ     D L  L+   +    I +        I++L
Sbjct: 2038 LDSANSEIADLKQKLAAAQSALGEQQKKAEDLLQKLNKAEQENQQIQAQNSNESKNISDL 2097

Query: 1239 WK--QHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETN---KIVTMEQ-V 1292
             +  ++L ++  D  K +  L+ +LSA E +   L   +Q  T+E  +   ++   E+ V
Sbjct: 2098 AEKLKNLQKKLNDEMKEKEALKSKLSAAEKEVSDLKSKLQQQTEENKDLKAQLAESEKNV 2157

Query: 1293 TSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIED 1329
              LQ+KLQ K + + +L+++ +D   ++   + ++E+
Sbjct: 2158 NDLQSKLQAKNKEMDDLKQQLSDAAQEVIAAQKKLEE 2194



 Score =  144 bits (349), Expect = 2e-32
 Identities = 232/1205 (19%), Positives = 518/1205 (42%), Gaps = 120/1205 (9%)

Query: 140  QLGDVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXX 199
            QL ++    N +++K + L   Q K+K         Q+++ EK + ++A N A       
Sbjct: 1091 QLNELEKQMNEVQKKADKLQPTQDKLKYA-------QDELTEKQKELDASN-ANNRDLQK 1142

Query: 200  XXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKL 259
                        ++ KQ++ +  +N +    +     ++ + ++ +K+  + +  + N  
Sbjct: 1143 QIKDLKKQNDDLDEQKQKLEEQLDNNVKA-GDVIGNLRKQISELLAKNKDLEAKNKDNNG 1201

Query: 260  LEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIA 319
             E A  E  LE   L  +LEQ                 + +  +   K +  +K S E  
Sbjct: 1202 DELAAKEAELE--SLKNQLEQIKKDLEEKEEEL-----KQVNDNLSAKDKELQKLSRENE 1254

Query: 320  NMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTA 379
              ++L K +E   + N ++   N +L+++L+T   E +     + +   L+ +   +N  
Sbjct: 1255 KNSKLQKDLEDANNQNKKLDDENNDLQSQLSTKDIELQKAQKEAGRLQNLVQKLEEQN-- 1312

Query: 380  SKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXX 439
              + +   + ++E L  + + +  + E+AK +   + L+K+    +   +EKD+      
Sbjct: 1313 KDLYNKLDEETAEKLKSNGEVRNAQLELAKTKANAEDLSKENEHLQEQNNEKDSFINELR 1372

Query: 440  XXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQ----LKQELNDEIKD 495
                      AQ +    + ++   +  + +  +++N     Q +    LK++LN+  K 
Sbjct: 1373 AKANE-----AQKKAGENEKLQN-QINDLNSQIDELNNAISAQNETINDLKKKLNEAQKK 1426

Query: 496  VN-VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSN 554
             N V+ L + L  A+E+  +  ++ID  N+ +   +   K   ++++  +    ++ DS 
Sbjct: 1427 ANQVEPLQQSLSDAKEENNEKQEKIDELNEKLRNAEKQFKEADQRVKDLLTEQQRLKDSY 1486

Query: 555  KEIVRLT-EELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRL 613
              I  ++ ++   L++K  E++  K  L+  L +  +G   + ++ +K  E+E   E  L
Sbjct: 1487 DNINNMSLQKEDELTKKENEVDTLKKALK-DLQNKTNGSN-DKEIAEKEQELEKQLEDAL 1544

Query: 614  KAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHL-----EEQI 668
            + +S ++S+  +   EL  L   YD + ++   +   + D + +E+ + +      ++++
Sbjct: 1545 RDLSNVKSELDNAKNELKQLHSSYDNLNNEHKSLESEKED-LENELNNANSTINSKDKEL 1603

Query: 669  DALSASKKELALVI---ENLKLDKEQLYGTIKDLENDKEDIMNKLQN------------- 712
              L    + L  V    ++LK + + L   I+ L+N   D+ NKLQ              
Sbjct: 1604 SKLQRDNERLQNVNKENDDLKKENKSLDDEIQTLKNSNNDLNNKLQRAQRQNELLQAAND 1663

Query: 713  -YIQENMDLTDKLEKMSAEKIS----------ELLAKINHEEQSKIQTQFGIDAKIQERD 761
                +N DL +KL +++ EKI+          EL   IN +E+ K   Q   D   Q  D
Sbjct: 1664 TLTNDNNDLNNKLTEVTKEKINADSLAKAAERELNNSINEKEELKASNQQLTD---QLND 1720

Query: 762  LYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQED 821
            L  +N   +L K  +   RL+  +  ++ +    ++KA+ +    Q + ++   Y  Q +
Sbjct: 1721 LMNKN--KDLKKKANDADRLQNLVDSLKSQLAEAQKKANTVVQNTQPQPQSNELYDRQLE 1778

Query: 822  ELVNRLAVLMD-HDRVVEKQLLEIEHENKELQKKNQILLEEN---QNLQISLSDMQQHYN 877
            +L   L  L D ++  V+K         +E Q+ +   ++ N   QN Q ++ ++++   
Sbjct: 1779 QLKQELEQLNDKYNEAVQKYHDADNSARQEKQQHDLDNIKNNAAIQNKQETIENLEKQIQ 1838

Query: 878  ALVEKANRTDLA-ESESTKYQTQLRDLESNLKRITHEHQT------LIVQKKKEIEDLE- 929
             L ++ N  + A E E  +++     L+  LK++  E +        ++ KK E+     
Sbjct: 1839 ELEKQQNALNAANEEEQKQHKLDANKLQDALKKLKDEQEKNSDLEKQLIAKKDELGKAND 1898

Query: 930  -----IEFNTQIESAIRDKKVLNEKYEKNIEYVTQ-LEAQLQEYKNNIENLNMNVEELNK 983
                 ++ N  +++  ++ K ++E Y+  I  + +  +A+L++ K+    L     E NK
Sbjct: 1899 RVKELLKENNNLKTEAKNNKDVSEFYQNEISMLDKDNKAKLEDLKDLNAKLAAEKAEKNK 1958

Query: 984  MNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQK-----INNAQVS 1038
            +   L      +Q   +    E+  NE+NK  A L+ + +  + L QK     + N    
Sbjct: 1959 VVAAL------EQANAANKVLEEANNELNKELAELQSRSDSGLPLAQKQEAEKLRNRVKE 2012

Query: 1039 YMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKET 1098
                V   E++  Q    + +++ ++   + ++ D KQ     Q  + EQ  + ++L + 
Sbjct: 2013 LQDKVRGLEAEKRQINDDVSDLQSKLDSANSEIADLKQKLAAAQSALGEQQKKAEDLLQ- 2071

Query: 1099 KLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQ 1158
                ++N  + E   I +     S+++ N+              K+ +E   ++E+  L+
Sbjct: 2072 ----KLNKAEQENQQIQAQ---NSNESKNISDLAEKLKNLQK--KLNDE---MKEKEALK 2119

Query: 1159 EQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVA 1218
             + +    E+ +  +K+ Q    N +L      +++ +N L+SKL+  N E D+L   ++
Sbjct: 2120 SKLSAAEKEVSDLKSKLQQQTEENKDLKAQLAESEKNVNDLQSKLQAKNKEMDDLKQQLS 2179

Query: 1219 ELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSS 1278
            +    + +A  Q+  E AE       Q  +D      ++ ++  + ++K  Q +   +  
Sbjct: 2180 DAAQEVIAA--QKKLEEAE------RQESSDIDVVARDIEIENESDDNKPPQTITEDEEM 2231

Query: 1279 TQEET 1283
            T  +T
Sbjct: 2232 TLLKT 2236



 Score =  126 bits (304), Expect = 5e-27
 Identities = 193/944 (20%), Positives = 409/944 (43%), Gaps = 77/944 (8%)

Query: 665  EEQIDALSASKKELALV---IENLKLDKEQLYGTIKDLEN---DKEDIMNKLQNYIQENM 718
            + ++    A+ +ELA     ++NL  DK+     IK+L++   D E   N+L +      
Sbjct: 14   DRELQTAKAASEELAKTNEQLDNLNKDKDN---KIKELQSKVNDLEKKSNQLDDANSRIK 70

Query: 719  DLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRI 778
            +L D+L +    K  +L  K+N + Q K+        ++ +    + + + E ++ +  +
Sbjct: 71   ELEDELTESETSK-DDLSNKLN-DLQKKLNELQKKANQLDQAKKDLADSQQENTEKQKEV 128

Query: 779  CRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVE 838
              L+  +  +E     L++K D L    ++ Q+   +   QE EL  +  VL +    ++
Sbjct: 129  DDLKTQLRDLEKEMKQLQKKNDDLEKANKDLQEKLEDSMKQESELSKKDQVLAN----LK 184

Query: 839  KQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQT 898
            K L +  ++ K+L+  NQ+    ++++     +++   + L +        +SE    + 
Sbjct: 185  KALADATNKVKDLE--NQLNGSNDKDIAAKEREIESLKSQLEDALRDLSNVKSELDNAKN 242

Query: 899  QLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVT 958
            +L+ L S+   + +EH++L    + E EDLE E N    S I  K     K +++ E + 
Sbjct: 243  ELKQLHSSYDNLNNEHKSL----ESEKEDLENELN-NANSTINSKDKELSKLQRDNERLQ 297

Query: 959  QLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQS---PDYTEQYINEINKLN 1015
             +  +  + K   ++L+  ++ L   N +L +K +Q++Q Q+       +   N+ N LN
Sbjct: 298  NVNKENDDLKKENKSLDDEIQTLKNSNNDLNNK-LQREQNQNKLLQAANDTLTNDNNDLN 356

Query: 1016 ALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSK 1075
              L   + + I    K N A+   ++ +++ E +L Q   +L     EM    K+L    
Sbjct: 357  DKLTSSNNDRIKAESKANTAERELINAIAEGE-ELKQTNKQLNGQLNEMNNNYKELQGKL 415

Query: 1076 QHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVD-XXXXX 1134
               E+    +   + +I++L++     E+   + E     + I  +   AN ++      
Sbjct: 416  NDLEKKANQLENANQRIQDLEQ-----ELAESQAESNGKDAKINELQKKANQLEPTEKKL 470

Query: 1135 XXXXXXXLKVQEEEEFIQERSVLQEQSAK-LNTELQECYTKIIQLETLNTELTGHDVVNQ 1193
                    K+Q+E + ++++    E++ K     ++E  ++  +LE          +   
Sbjct: 471  VDKQNENDKLQKELDELKDKYDQLEKALKAAENRVKELLSQNEKLENSLDNANNLSLQKG 530

Query: 1194 EQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQ----RGFEIAELWKQHLAQREAD 1249
            +++++    L  L   N  L + V +L S      D     +  EI  L K  L Q + D
Sbjct: 531  DELSKRNETLADLKKRNQELEARVRDLESQNDDEKDNELAAKDSEIQNL-KSQLEQTKKD 589

Query: 1250 FQKTEHELRV---QLSAFESKYEQL------LDSVQSSTQEETNKIVTME-QVTSLQNKL 1299
               T+ +L+     LSA + + ++L      +  +    +E  ++I  +E +   LQ++L
Sbjct: 590  LNDTQEDLKTANNDLSAKDKEIQKLKRDNEKIAKLNEDLKEANDEIKKLENEKDDLQSQL 649

Query: 1300 QDKEEHLRNLQEKYADVINQIEILRSEIE--DEKV-AFXXXXXXXXXXXXXXXXDLRTEN 1356
             DK+  L+N   +     N+   L+ +I   DEK+                   +L T N
Sbjct: 650  SDKDSKLQNAMREKDRANNENATLKQQINECDEKLKKETGEKIKLNGQKGDLERELATAN 709

Query: 1357 QSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEI 1416
             S +Q +E +     ++  Q K +             ++ND + K       L+ +  ++
Sbjct: 710  ASAQQQKEAT--EFAQQQVQEKDA------RNKELQNKINDLQKKA-NAADNLQQQVDQL 760

Query: 1417 YQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETM 1476
                 +   ++  ++ +    +++L+E  K+   L   K+S L   + ++ E  N     
Sbjct: 761  KSMLDDANKSINDKDSQINEKQKELIETRKKASALEPTKQS-LKDTQAELTEKQNDLNNA 819

Query: 1477 -QKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVT 1535
              K  E+ER   ++EL  +I +   LN++  +L + L+++V K +++   +E    +I  
Sbjct: 820  NNKNRELERE--LKELKKQIGD---LNRENNDLKEQLDDKV-KNDDI---IEKLRKQIDE 870

Query: 1536 LNDEITNLQNMVRA-SSSKIQKHVSFASDTKQGRDEQLDNTMNK 1578
            LN +I  LQ+     +SS +++ ++     KQ    +L+ T NK
Sbjct: 871  LNAKIQELQSQKPVDNSSALEEKINELQKAKQ----ELEETENK 910



 Score =  110 bits (265), Expect = 3e-22
 Identities = 173/838 (20%), Positives = 373/838 (44%), Gaps = 101/838 (12%)

Query: 801  QLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLE 860
            +LGS  +   +         +EL      L + ++  + ++ E++ +  +L+KK+  L +
Sbjct: 5    KLGSQAKAADRELQTAKAASEELAKTNEQLDNLNKDKDNKIKELQSKVNDLEKKSNQLDD 64

Query: 861  EN-----------------QNLQISLSDMQQHYNALVEKAN-----RTDLAES--ESTKY 896
             N                  +L   L+D+Q+  N L +KAN     + DLA+S  E+T+ 
Sbjct: 65   ANSRIKELEDELTESETSKDDLSNKLNDLQKKLNELQKKANQLDQAKKDLADSQQENTEK 124

Query: 897  QTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEY 956
            Q ++ DL++ L+ +  E + L  QKK   +DLE + N  ++  + D      +  K  + 
Sbjct: 125  QKEVDDLKTQLRDLEKEMKQL--QKKN--DDLE-KANKDLQEKLEDSMKQESELSKKDQV 179

Query: 957  VTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNA 1016
            +  L+  L +  N +++L   +   N  ++   ++ ++  ++Q  D      N  ++L+ 
Sbjct: 180  LANLKKALADATNKVKDLENQLNGSNDKDIAAKEREIESLKSQLEDALRDLSNVKSELDN 239

Query: 1017 LLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEE---MQRVSKQLLD 1073
              K + +++ +    +NN   S  S   D E++L    + + + ++E   +QR +++L +
Sbjct: 240  -AKNELKQLHSSYDNLNNEHKSLESEKEDLENELNNANSTINSKDKELSKLQRDNERLQN 298

Query: 1074 SKQHNEELQILVREQDDQIKELKETK--LTFEMNIPKTEGMIISSTIEPMSDDANNVDXX 1131
              + N++L+   +  DD+I+ LK +   L  ++   + +  ++ +  + +++D N+++  
Sbjct: 299  VNKENDDLKKENKSLDDEIQTLKNSNNDLNNKLQREQNQNKLLQAANDTLTNDNNDLNDK 358

Query: 1132 XXXXXXXXXXLKVQ---EEEEFIQ---ERSVLQEQSAKLNTELQECYTKIIQLE-TLN-T 1183
                       + +    E E I    E   L++ + +LN +L E      +L+  LN  
Sbjct: 359  LTSSNNDRIKAESKANTAERELINAIAEGEELKQTNKQLNGQLNEMNNNYKELQGKLNDL 418

Query: 1184 ELTGHDVVNQEQ-INQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQH 1242
            E   + + N  Q I  L+ +L +   E++   + + EL+   +         + +  +  
Sbjct: 419  EKKANQLENANQRIQDLEQELAESQAESNGKDAKINELQKKANQLEPTEKKLVDKQNEND 478

Query: 1243 LAQREADFQKTEH-ELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQ--NKL 1299
              Q+E D  K ++ +L   L A E++ ++LL     S  E+    +      SLQ  ++L
Sbjct: 479  KLQKELDELKDKYDQLEKALKAAENRVKELL-----SQNEKLENSLDNANNLSLQKGDEL 533

Query: 1300 QDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSY 1359
              + E L +L+++  ++  ++  L S+ +DEK                   D  +E Q+ 
Sbjct: 534  SKRNETLADLKKRNQELEARVRDLESQNDDEK------------DNELAAKD--SEIQNL 579

Query: 1360 KQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQK 1419
            K   EQ+  ++N+    LK ++              ND  AK  E+  Q   +D+E   K
Sbjct: 580  KSQLEQTKKDLNDTQEDLKTAN--------------NDLSAKDKEI--QKLKRDNEKIAK 623

Query: 1420 THEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELA-ILRLKMHENANHYETMQK 1478
             +E    L + NDE + +  +  + + ++ D    K+S+L   +R K   N  +    Q+
Sbjct: 624  LNE---DLKEANDEIKKLENEKDDLQSQLSD----KDSKLQNAMREKDRANNENATLKQQ 676

Query: 1479 ESEIERVKLIEELNVKIT---ESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVT 1535
             +E +  KL +E   KI    +   L +++A  N + +++   T   Q  ++ ++     
Sbjct: 677  INECDE-KLKKETGEKIKLNGQKGDLERELATANASAQQQKEATEFAQQQVQEKDARNKE 735

Query: 1536 LNDEITNLQNMVRASSS------KIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRA 1587
            L ++I +LQ    A+ +      +++  +  A+ +   +D Q+ N   KEL++   +A
Sbjct: 736  LQNKINDLQKKANAADNLQQQVDQLKSMLDDANKSINDKDSQI-NEKQKELIETRKKA 792



 Score = 79.0 bits (186), Expect = 1e-12
 Identities = 127/621 (20%), Positives = 245/621 (39%), Gaps = 38/621 (6%)

Query: 981  LNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYM 1040
            + K+ L    K   ++   +   +E+      +L+ L K KD +I  L  K+N+ +    
Sbjct: 1    MEKLKLGSQAKAADRELQTAKAASEELAKTNEQLDNLNKDKDNKIKELQSKVNDLE-KKS 59

Query: 1041 SMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKL 1100
            + + D  S++ +   +L   E     +S +L D ++   ELQ    + D   K+L +++ 
Sbjct: 60   NQLDDANSRIKELEDELTESETSKDDLSNKLNDLQKKLNELQKKANQLDQAKKDLADSQQ 119

Query: 1101 TFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQ 1160
              E    + E   + + +  +  +   +             L+ + E+   QE  + ++ 
Sbjct: 120  --ENTEKQKEVDDLKTQLRDLEKEMKQLQKKNDDLEKANKDLQEKLEDSMKQESELSKKD 177

Query: 1161 S--AKLNTELQECYTKIIQLETLNTELTGHDVVNQE-QINQLKSKLEQLNTENDNLLSTV 1217
               A L   L +   K+  LE         D+  +E +I  LKS+LE    +  N+ S +
Sbjct: 178  QVLANLKKALADATNKVKDLENQLNGSNDKDIAAKEREIESLKSQLEDALRDLSNVKSEL 237

Query: 1218 AELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQS 1277
               ++ +     Q       L  +H    E++ +  E+EL    S   SK ++ L  +Q 
Sbjct: 238  DNAKNELK----QLHSSYDNLNNEH-KSLESEKEDLENELNNANSTINSK-DKELSKLQR 291

Query: 1278 STQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXX 1337
              +   N     + +      L D+ + L+N      + + + +     ++         
Sbjct: 292  DNERLQNVNKENDDLKKENKSLDDEIQTLKNSNNDLNNKLQREQNQNKLLQAANDTLTND 351

Query: 1338 XXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVND 1397
                         D R + +S     E+ ++N   E  +LK+++               +
Sbjct: 352  NNDLNDKLTSSNND-RIKAESKANTAERELINAIAEGEELKQTNKQLNGQLNEMNNNYKE 410

Query: 1398 AEAKVLEL---THQLELKDSEIYQKTHEYTITLTQRN------DEFENVRQQLVEYEKRI 1448
             + K+ +L    +QLE  +  I     E   +  + N      +E +    QL   EK++
Sbjct: 411  LQGKLNDLEKKANQLENANQRIQDLEQELAESQAESNGKDAKINELQKKANQLEPTEKKL 470

Query: 1449 EDLTYEKESELAILRLKMHENANHYETMQK--ESEIERVKLIEELNVKITESVSLNKQVA 1506
             D    K++E   L+ ++ E  + Y+ ++K  ++   RVK +   N K+  S+  N    
Sbjct: 471  VD----KQNENDKLQKELDELKDKYDQLEKALKAAENRVKELLSQNEKLENSLD-NANNL 525

Query: 1507 ELNKALEEEVAKTNEMQTALE--NQEIEIVTLNDEITN---LQNMVRASSSKIQKHVSFA 1561
             L K   +E++K NE    L+  NQE+E    + E  N     N + A  S+IQ   S  
Sbjct: 526  SLQKG--DELSKRNETLADLKKRNQELEARVRDLESQNDDEKDNELAAKDSEIQNLKSQL 583

Query: 1562 SDTKQG-RDEQLD-NTMNKEL 1580
              TK+   D Q D  T N +L
Sbjct: 584  EQTKKDLNDTQEDLKTANNDL 604


>UniRef50_A2DKP8 Cluster: Viral A-type inclusion protein, putative;
            n=1; Trichomonas vaginalis G3|Rep: Viral A-type inclusion
            protein, putative - Trichomonas vaginalis G3
          Length = 1618

 Score =  178 bits (434), Expect = 9e-43
 Identities = 285/1357 (21%), Positives = 604/1357 (44%), Gaps = 132/1357 (9%)

Query: 213  DTK-QQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271
            DT+ QQ+   Q N I+   + ++ +  L +D +      S ++  N +++  + E+S   
Sbjct: 252  DTELQQLRSNQNNNISNLIQSQNNQYSLKEDNKDSQELSSQIQNLNSMVQKLQNELS--E 309

Query: 272  SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEE-KTEIEEKGSLEIA---NMTELTKK 327
            SKL  E                   K  +E      K ++E+  +   A   N  +L + 
Sbjct: 310  SKLLNEQNSSKIDELNALNNSLIDEKSRLESELSNAKAKVEQSNTNSSAMAQNNAKLQEL 369

Query: 328  IELLEHLNCQIRQTNKELENKL----ATMGTESKAVSSPSKKGSPLISRKSGRNTA---- 379
             E+++ L  +  Q  K+L++++    A +   S+  +  S++ S L       NT     
Sbjct: 370  NEMIQKLTNEKNQLEKDLKSQIEQDKAKLNELSQQNNKISEEKSQLQKIYEQNNTKMQEL 429

Query: 380  -SKMKSPWSQLSS-ETLNQDTDKKIN--KNEIAKLEMVIQSLNKDL-VDKEYVISEKDTX 434
              K+ +  ++++    LNQ     +N  K++  K    +Q LN++L  +K +++ + +  
Sbjct: 430  NQKLANSEAKINDLNALNQKISGDLNNSKSQKEKESSKLQQLNQNLSEEKAFILQQLNET 489

Query: 435  XXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTED--VNEIAKVQEQLKQELNDE 492
                       D    +L+     + +  + I   ++ +      I+K++++ K +L  +
Sbjct: 490  KISMQNLMEENDHFSNELKQSKSLNDQNNAKIKELSDQKSQLQTNISKLEKE-KSDLISK 548

Query: 493  IKDVN--VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHK-----LKLKQMQKTID 545
            + DVN  V+   +KL+S   +  QL +E+  A+K++I+ +SN K      K+ Q+Q  ++
Sbjct: 549  LNDVNKLVEQSSQKLQSNNNEKLQLENEL-KASKSLIE-QSNIKEQELNQKISQIQNQLN 606

Query: 546  NF-SKVSDSNKEIVRLTEE---LHHLSQKVAELEEEKGNLQ-LHLVDYDSGRMIES---- 596
            N  +K+ + ++ I+ L  E   L  + QK  E  E   NLQ +  ++ +   +I+S    
Sbjct: 607  NSNAKIQELSENIMNLKSENAKLREMKQKSEENSENNINLQKIEEMNREKEELIKSYNDK 666

Query: 597  --DVYKKMIEMENLAETRLKAISLLESQKFDLVQELH-----ILQQKYDEVEDKLADISQ 649
              ++    I++ N        IS L+++K ++   +      + +QK + +E    +I  
Sbjct: 667  IDNMTNDSIQLVNQISELKNTISKLQNEKIEIQNRMKREVSAVTEQKNESIERLQQEI-- 724

Query: 650  LQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIK-DLENDKEDIMN 708
            L+ D + +E KS ++ E ++ L+   +E      N  LD ++ +  +K + E  K+D  N
Sbjct: 725  LKKDGIINEQKS-NISE-LEQLALQLQE----ENNTFLDSKEEFDKLKEEYEKMKQDSNN 778

Query: 709  KLQNYIQENM-DLTDKLEK-----MSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDL 762
               N +++N+  LT  L+K      +A+  +E L + N+ +Q  I     ID+  Q  + 
Sbjct: 779  PKINELEQNVKQLTKALQKTLNDLKAAKSENEQLLQSNNSDQKIISLNKKIDSLNQSIND 838

Query: 763  YIENIESELS-------KYKSRICRL-----EESIAVMEDRRY--SLERKADQLGSYLQE 808
            Y E  ++  S       KY+ +I ++     E+++ + E  +    LE++  +L + L E
Sbjct: 839  YEETTKALASENYEITQKYEQQINQISNQLNEKNVLLQEKEKQINDLEQENKELNNQLNE 898

Query: 809  KQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQIS 868
             Q+   E   +  + +N L  + +  + V  Q++E++ ENKEL   N  L E  Q  + S
Sbjct: 899  MQQDKEEKEERYQQQINDLQKISNEQQNV--QIIELQTENKEL---NNQLNEMQQIKEKS 953

Query: 869  LSDMQQHYNALV-EKANRTDLAESESTKYQTQLRDLESNLKRI-----THEHQTLIVQKK 922
             ++ Q+  N L+  K+N +++ ES   K Q    ++ +  K+I     T ++   I+  +
Sbjct: 954  EAEYQKQINDLLSNKSNNSEMIESLRRKLQQNEEEITNYKKQINELNNTKQNNEEIINYQ 1013

Query: 923  KEIEDLEIEFN--TQIESAIRD-KKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVE 979
            K+I +L+ E N   Q    I + KK + E  +++ E V   + Q+++ KN + +L  N +
Sbjct: 1014 KQINELKKELNITKQNNDLIANYKKQIEELSKQSNEEVVNYQKQVEDLKNKLIDLQQNNQ 1073

Query: 980  ELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSY 1039
            E+ K   + ID+ + ++++ S     +   ++N+ N  + +  ++I  LNQK+ + Q + 
Sbjct: 1074 EIAKYQ-QQIDE-LNEEKSNSEKQINELNQKLNQNNEEINKYQKQIEDLNQKLKDLQENN 1131

Query: 1040 MSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETK 1099
               ++ Y++++     K +   EE+    K++ + K+  +     + E ++ + E K+++
Sbjct: 1132 QE-IAKYQNEVDDLKKKFDVSNEEIANKEKEIEEMKKKEQNYLKQISELNNHLME-KQSE 1189

Query: 1100 LTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQE 1159
            +   +N  K +  I +   +  + + N  D             K+++ E   QE + L +
Sbjct: 1190 IV-NLN-SKLDNQIYNLNTKKQNLEMNLNDLQT----------KLKQIE---QENANLSK 1234

Query: 1160 QSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAE 1219
            ++  L  E Q      ++ +  N +LT      +++  +L  +L ++   N N  S + +
Sbjct: 1235 RNKDLENESQNQAKITLETQNKNVDLTNKVKSLEQESQKLIQQLSEITKLNANYSSELED 1294

Query: 1220 LRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSST 1279
            LR  +SS                L + + +  + E  LR  ++   ++ + L + +Q   
Sbjct: 1295 LREKVSSLTTS---------NNELTKSKQESTELEEHLRKAVNDLTNENQSLTNGLQ--- 1342

Query: 1280 QEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEI--EDEKVA--FX 1335
              ET ++V  ++ T  +   Q       N Q K    I Q ++ +SEI   DE+V     
Sbjct: 1343 --ETERLVAEQRKTMKEQHDQFTALEKENQQLKSEKTILQKQLEKSEIAHHDEEVVKEKE 1400

Query: 1336 XXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQL-KKSSXXXXXXXXXXXXR 1394
                             +   Q    +Q+Q    ++++N  +  + S            R
Sbjct: 1401 ETIQGLKKLLQRYVNTTKRNQQQIDDLQQQVTTLLSQQNTSVGTEDSNKYLETVHRQEER 1460

Query: 1395 VNDAEAKV--LELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQL-VEYEKRIEDL 1451
            + + E ++   + T  +E K  ++ +   + +   T+   E E++ +QL  E EKR    
Sbjct: 1461 IKELEERLESSQATKDIENKAQKMAKMLEKSSRQYTELLSEKEDILKQLNQEKEKRFAKF 1520

Query: 1452 TYEKESELAILRLKMHENANHYETMQKESEIERVKLI 1488
               K+    +  L   E     +    E+E E++K++
Sbjct: 1521 EVSKDVFFEMAELTPEEEERRRKEELSEAENEKIKVM 1557



 Score =  171 bits (416), Expect = 1e-40
 Identities = 259/1330 (19%), Positives = 575/1330 (43%), Gaps = 128/1330 (9%)

Query: 323  ELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKM 382
            ++ +K E+++ L+ +I+  + +L     T  +E +A  +  K+      +K+ +   +++
Sbjct: 136  QIAEKEEIIQALSQKIQTYSDQLA--ATTTPSEFEAKYNAEKEAFSKF-KKAAKAAIAQV 192

Query: 383  KSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXX 442
            ++   +L ++  N  TD +  K    + E  +Q + K+L  +   +  ++T         
Sbjct: 193  QTENEELKAKLANASTDNEYTKQLEQQREEALQKV-KELTSRNLELEAQETDFISKLEEL 251

Query: 443  XGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVN-VKDL 501
               DT + QL+     ++   +LI    N   + E  K  ++L  ++ +    V  +++ 
Sbjct: 252  ---DTELQQLRSNQNNNIS--NLIQSQNNQYSLKEDNKDSQELSSQIQNLNSMVQKLQNE 306

Query: 502  IEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLT 561
            + + K   EQ +   DE++A N ++I  KS  + +L   +  ++  +  S +   + +  
Sbjct: 307  LSESKLLNEQNSSKIDELNALNNSLIDEKSRLESELSNAKAKVEQSNTNSSA---MAQNN 363

Query: 562  EELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYK--KMIEMENLAETRLKAISLL 619
             +L  L++ + +L  EK  L+  L        IE D  K  ++ +  N        +  +
Sbjct: 364  AKLQELNEMIQKLTNEKNQLEKDLKS-----QIEQDKAKLNELSQQNNKISEEKSQLQKI 418

Query: 620  ESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELA 679
              Q    +QEL+   QK    E K+ D++ L + ++  ++ +   +++ +  S+  ++L 
Sbjct: 419  YEQNNTKMQELN---QKLANSEAKINDLNAL-NQKISGDLNNSKSQKEKE--SSKLQQL- 471

Query: 680  LVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKI 739
                N  L +E+ +  ++ L   K      +QN ++EN   +++L K S     +  AKI
Sbjct: 472  ----NQNLSEEKAF-ILQQLNETKIS----MQNLMEENDHFSNEL-KQSKSLNDQNNAKI 521

Query: 740  NHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKA 799
                  K Q Q  I    +E+     ++ S+L+     + +  + +    + +  LE + 
Sbjct: 522  KELSDQKSQLQTNISKLEKEKS----DLISKLNDVNKLVEQSSQKLQSNNNEKLQLENEL 577

Query: 800  DQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHEN---KELQKKNQ 856
                S +++      E   +  ++ N+L       + + + ++ ++ EN   +E+++K++
Sbjct: 578  KASKSLIEQSNIKEQELNQKISQIQNQLNNSNAKIQELSENIMNLKSENAKLREMKQKSE 637

Query: 857  ILLEENQNLQISLSDMQQHYNALVEKAN-RTDLAESESTKYQTQLRDLESNLKRITHEHQ 915
               E N NLQ  + +M +    L++  N + D   ++S +   Q+ +L++ + ++ +E  
Sbjct: 638  ENSENNINLQ-KIEEMNREKEELIKSYNDKIDNMTNDSIQLVNQISELKNTISKLQNEKI 696

Query: 916  TLIVQKKKEIEDLEIEFNTQIESAIRD--KK--VLNEKYEKNIEYVTQLEAQLQEYKNNI 971
             +  + K+E+  +  + N  IE   ++  KK  ++NE+ + NI  + QL  QLQE  N  
Sbjct: 697  EIQNRMKREVSAVTEQKNESIERLQQEILKKDGIINEQ-KSNISELEQLALQLQEENNTF 755

Query: 972  ----ENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNA-------LLKQ 1020
                E  +   EE  KM  +  +  + + +      T+     +N L A       LL+ 
Sbjct: 756  LDSKEEFDKLKEEYEKMKQDSNNPKINELEQNVKQLTKALQKTLNDLKAAKSENEQLLQS 815

Query: 1021 K--DEEIIALNQKI-------NNAQVSYMSMVSD-------YESKLAQFTTKLENMEEEM 1064
               D++II+LN+KI       N+ + +  ++ S+       YE ++ Q + +L      +
Sbjct: 816  NNSDQKIISLNKKIDSLNQSINDYEETTKALASENYEITQKYEQQINQISNQLNEKNVLL 875

Query: 1065 QRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMN----IPKTEGMIISSTIEP 1120
            Q   KQ+ D +Q N+EL   + E   Q KE KE +   ++N    I   +  +    ++ 
Sbjct: 876  QEKEKQINDLEQENKELNNQLNEMQ-QDKEEKEERYQQQINDLQKISNEQQNVQIIELQT 934

Query: 1121 MSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKII---- 1176
             + + NN                 ++  + +  +S   E    L  +LQ+   +I     
Sbjct: 935  ENKELNNQLNEMQQIKEKSEAEYQKQINDLLSNKSNNSEMIESLRRKLQQNEEEITNYKK 994

Query: 1177 QLETLN-TELTGHDVVN-QEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFE 1234
            Q+  LN T+    +++N Q+QIN+LK +L      ND     +A  +  I     Q   E
Sbjct: 995  QINELNNTKQNNEEIINYQKQINELKKELNITKQNND----LIANYKKQIEELSKQSNEE 1050

Query: 1235 IAELWKQ--HLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQV 1292
            +    KQ   L  +  D Q+   E+        +KY+Q +D +    +E++N   + +Q+
Sbjct: 1051 VVNYQKQVEDLKNKLIDLQQNNQEI--------AKYQQQIDELN---EEKSN---SEKQI 1096

Query: 1293 TSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDL 1352
              L  KL    E +   Q++  D+  +++ L+    ++++A                 DL
Sbjct: 1097 NELNQKLNQNNEEINKYQKQIEDLNQKLKDLQEN--NQEIA----------KYQNEVDDL 1144

Query: 1353 RTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELK 1412
            + +      +  + I N  +E  ++KK               + + +++++ L  +L+ +
Sbjct: 1145 KKKFD----VSNEEIANKEKEIEEMKKKEQNYLKQISELNNHLMEKQSEIVNLNSKLDNQ 1200

Query: 1413 DSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANH 1472
               +  K     + L     + + + Q+     KR +DL  E +++  I     ++N + 
Sbjct: 1201 IYNLNTKKQNLEMNLNDLQTKLKQIEQENANLSKRNKDLENESQNQAKITLETQNKNVDL 1260

Query: 1473 YETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEM-QTALENQEI 1531
               + K  E E  KLI++L+     + + + ++ +L + +       NE+ ++  E+ E+
Sbjct: 1261 TNKV-KSLEQESQKLIQQLSEITKLNANYSSELEDLREKVSSLTTSNNELTKSKQESTEL 1319

Query: 1532 EIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDL 1591
            E   L   + +L N  ++ ++ +Q+     ++ ++   EQ D     E  +   ++E  +
Sbjct: 1320 E-EHLRKAVNDLTNENQSLTNGLQETERLVAEQRKTMKEQHDQFTALEKENQQLKSEKTI 1378

Query: 1592 AMYMLHQRDV 1601
                L + ++
Sbjct: 1379 LQKQLEKSEI 1388



 Score =  171 bits (416), Expect = 1e-40
 Identities = 254/1283 (19%), Positives = 562/1283 (43%), Gaps = 96/1283 (7%)

Query: 337  QIRQTNKELENKLATMGTE---SKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSET 393
            Q++  N+EL+ KLA   T+   +K +    ++    +   + RN   ++++  +   S+ 
Sbjct: 191  QVQTENEELKAKLANASTDNEYTKQLEQQREEALQKVKELTSRNL--ELEAQETDFISKL 248

Query: 394  LNQDTD-KKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQL 452
               DT+ +++  N+   +  +IQS N      +Y + E +             ++++ +L
Sbjct: 249  EELDTELQQLRSNQNNNISNLIQSQN-----NQYSLKEDNKDSQELSSQIQNLNSMVQKL 303

Query: 453  QLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQL---KQELNDEIKDVNVKDLIEKLKSAE 509
            Q E  +     S +    N+  ++E+  +   L   K  L  E+   N K  +E+  +  
Sbjct: 304  QNELSE-----SKLLNEQNSSKIDELNALNNSLIDEKSRLESELS--NAKAKVEQSNTNS 356

Query: 510  EQITQLNDEIDAANKNMIKVKSNHKLKL-KQMQKTID-NFSKVSDSNKEIVRLTEELHHL 567
              + Q N ++   N+ MI+  +N K +L K ++  I+ + +K+++ +++  +++EE   L
Sbjct: 357  SAMAQNNAKLQELNE-MIQKLTNEKNQLEKDLKSQIEQDKAKLNELSQQNNKISEEKSQL 415

Query: 568  SQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMI--EMENLAETRLKAISLLESQKFD 625
             QK+ E    K       +     ++ + +   + I  ++ N    + K  S L+    +
Sbjct: 416  -QKIYEQNNTKMQELNQKLANSEAKINDLNALNQKISGDLNNSKSQKEKESSKLQQLNQN 474

Query: 626  LVQELHILQQKYDEVEDKLADISQLQSDQVCSEIK-SVHLEEQ----IDALSASKKELAL 680
            L +E   + Q+ +E +  + ++ + ++D   +E+K S  L +Q    I  LS  K +L  
Sbjct: 475  LSEEKAFILQQLNETKISMQNLME-ENDHFSNELKQSKSLNDQNNAKIKELSDQKSQLQT 533

Query: 681  VIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLE-KMSAEKISELLAKI 739
             I  L+ +K  L   + D+    E    KLQ+   E + L ++L+   S  + S +  + 
Sbjct: 534  NISKLEKEKSDLISKLNDVNKLVEQSSQKLQSNNNEKLQLENELKASKSLIEQSNIKEQE 593

Query: 740  NHEEQSKIQTQF-GIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERK 798
             +++ S+IQ Q    +AKIQE    I N++SE +K +    + EE+     +   +L+ K
Sbjct: 594  LNQKISQIQNQLNNSNAKIQELSENIMNLKSENAKLREMKQKSEEN----SENNINLQ-K 648

Query: 799  ADQLGSYLQEKQKAYSE----YTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKK 854
             +++    +E  K+Y++     T    +LVN+++ L +    ++ + +EI  +N+  ++ 
Sbjct: 649  IEEMNREKEELIKSYNDKIDNMTNDSIQLVNQISELKNTISKLQNEKIEI--QNRMKREV 706

Query: 855  NQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQ-----LRDLESNLKR 909
            + +  ++N++++    ++ +    + E+  +++++E E    Q Q       D +    +
Sbjct: 707  SAVTEQKNESIERLQQEILKKDGIINEQ--KSNISELEQLALQLQEENNTFLDSKEEFDK 764

Query: 910  ITHEHQTLIVQ----KKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQ 965
            +  E++ +       K  E+E    +    ++  + D K    + E+ ++     + ++ 
Sbjct: 765  LKEEYEKMKQDSNNPKINELEQNVKQLTKALQKTLNDLKAAKSENEQLLQ-SNNSDQKII 823

Query: 966  EYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEI 1025
                 I++LN ++ +  +    L  ++ +  Q +      Q  N++N+ N LL++K+++I
Sbjct: 824  SLNKKIDSLNQSINDYEETTKALASENYEITQ-KYEQQINQISNQLNEKNVLLQEKEKQI 882

Query: 1026 IAL---NQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQ 1082
              L   N+++NN          + E +  Q    L+ +  E Q V  Q+++ +  N+EL 
Sbjct: 883  NDLEQENKELNNQLNEMQQDKEEKEERYQQQINDLQKISNEQQNV--QIIELQTENKELN 940

Query: 1083 ILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSD--DANNVDXXXXXXXXXXX 1140
              + E   QIKE  E +   ++N   +     S  IE +      N  +           
Sbjct: 941  NQLNEM-QQIKEKSEAEYQKQINDLLSNKSNNSEMIESLRRKLQQNEEEITNYKKQINEL 999

Query: 1141 XLKVQEEEEFIQERSVLQEQSAKL-----NTELQECYTKIIQLETLNTELTGHDVVN-QE 1194
                Q  EE I  +  + E   +L     N +L   Y K  Q+E L+ + +  +VVN Q+
Sbjct: 1000 NNTKQNNEEIINYQKQINELKKELNITKQNNDLIANYKK--QIEELSKQ-SNEEVVNYQK 1056

Query: 1195 QINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTE 1254
            Q+  LK+KL  L   N  +     ++   ++        +I EL  Q L Q   +  K +
Sbjct: 1057 QVEDLKNKLIDLQQNNQEIAKYQQQI-DELNEEKSNSEKQINEL-NQKLNQNNEEINKYQ 1114

Query: 1255 HELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQN-KLQDKEEHLRNLQEKY 1313
                 Q+     K + L ++ Q   + + N++  +++   + N ++ +KE+ +  +++K 
Sbjct: 1115 K----QIEDLNQKLKDLQENNQEIAKYQ-NEVDDLKKKFDVSNEEIANKEKEIEEMKKKE 1169

Query: 1314 ADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEE 1373
             + + QI  L + + +++                     +    +   +Q + +  I +E
Sbjct: 1170 QNYLKQISELNNHLMEKQSEIVNLNSKLDNQIYNLNTKKQNLEMNLNDLQTK-LKQIEQE 1228

Query: 1374 NAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQ---LELKDSEIYQKTHEYTITLTQR 1430
            NA L K +               + + K ++LT++   LE +  ++ Q+  E T      
Sbjct: 1229 NANLSKRNKDLENESQNQAKITLETQNKNVDLTNKVKSLEQESQKLIQQLSEITKLNANY 1288

Query: 1431 NDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEE 1490
            + E E++R+++        +LT  K+ E   L   + +  N   T + +S    ++  E 
Sbjct: 1289 SSELEDLREKVSSLTTSNNELTKSKQ-ESTELEEHLRKAVNDL-TNENQSLTNGLQETER 1346

Query: 1491 LNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQ--EIEIVTLNDEIT-NLQNMV 1547
            L   + E     K+  +   ALE+E  +    +T L+ Q  + EI   ++E+    +  +
Sbjct: 1347 L---VAEQRKTMKEQHDQFTALEKENQQLKSEKTILQKQLEKSEIAHHDEEVVKEKEETI 1403

Query: 1548 RASSSKIQKHVSFASDTKQGRDE 1570
            +     +Q++V+     +Q  D+
Sbjct: 1404 QGLKKLLQRYVNTTKRNQQQIDD 1426



 Score =  164 bits (399), Expect = 2e-38
 Identities = 236/1136 (20%), Positives = 497/1136 (43%), Gaps = 100/1136 (8%)

Query: 502  IEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLT 561
            +E LK  + QI +  +EI  A    I+  S+      Q+  T       +  N E    +
Sbjct: 127  LEALKEKDRQIAE-KEEIIQALSQKIQTYSD------QLAATTTPSEFEAKYNAEKEAFS 179

Query: 562  EELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLES 621
            +        +A+++ E   L+  L +  +      + Y K +E +   E  L+ +  L S
Sbjct: 180  KFKKAAKAAIAQVQTENEELKAKLANAST-----DNEYTKQLEQQR--EEALQKVKELTS 232

Query: 622  QKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALV 681
            +  +L  +      K +E++ +L  +   Q++ + + I+S + +  +   +   +EL+  
Sbjct: 233  RNLELEAQETDFISKLEELDTELQQLRSNQNNNISNLIQSQNNQYSLKEDNKDSQELSSQ 292

Query: 682  IENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINH 741
            I+NL    ++L   + + +   E   +K+      N  L D+  ++ +E +S   AK+  
Sbjct: 293  IQNLNSMVQKLQNELSESKLLNEQNSSKIDELNALNNSLIDEKSRLESE-LSNAKAKVEQ 351

Query: 742  ---------EEQSKIQTQFGIDAKI-QERDLYIENIESELSKYKSRICRLEESIAVMEDR 791
                     +  +K+Q    +  K+  E++   ++++S++ + K+++  L +    + + 
Sbjct: 352  SNTNSSAMAQNNAKLQELNEMIQKLTNEKNQLEKDLKSQIEQDKAKLNELSQQNNKISEE 411

Query: 792  RYSLERKADQLGSYLQE-KQK-AYSEYTIQEDELVNRLAV--LMDHDRVVEKQLLEIEHE 847
            +  L++  +Q  + +QE  QK A SE  I +   +N+     L +     EK+  +++  
Sbjct: 412  KSQLQKIYEQNNTKMQELNQKLANSEAKINDLNALNQKISGDLNNSKSQKEKESSKLQQL 471

Query: 848  NKELQKKNQILLEENQNLQISLSDMQQ---HY-NALVEKANRTDLAESESTKYQTQLRDL 903
            N+ L ++   +L++    +IS+ ++ +   H+ N L +  +  D   ++  +   Q   L
Sbjct: 472  NQNLSEEKAFILQQLNETKISMQNLMEENDHFSNELKQSKSLNDQNNAKIKELSDQKSQL 531

Query: 904  ESNLKRITHEHQTLI-----VQKKKEIEDLEIEFNT----QIESAIRDKKVLNEKYEKNI 954
            ++N+ ++  E   LI     V K  E    +++ N     Q+E+ ++  K L E  + NI
Sbjct: 532  QTNISKLEKEKSDLISKLNDVNKLVEQSSQKLQSNNNEKLQLENELKASKSLIE--QSNI 589

Query: 955  EYVTQLEAQLQEYKNNIENLNMNVEEL--NKMNLELIDKHVQKQQTQSPDYTEQYINEIN 1012
            +   +L  ++ + +N + N N  ++EL  N MNL+  +  +++ + +S + +E  IN + 
Sbjct: 590  KE-QELNQKISQIQNQLNNSNAKIQELSENIMNLKSENAKLREMKQKSEENSENNIN-LQ 647

Query: 1013 KLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLL 1072
            K+  + ++K+E I + N KI+N     + +V+   S+L    +KL+N + E+Q   K+ +
Sbjct: 648  KIEEMNREKEELIKSYNDKIDNMTNDSIQLVNQI-SELKNTISKLQNEKIEIQNRMKREV 706

Query: 1073 DS--KQHNEELQIL----------VREQDDQIKELKETKLTF--EMNI---PKTEGMIIS 1115
             +  +Q NE ++ L          + EQ   I EL++  L    E N     K E   + 
Sbjct: 707  SAVTEQKNESIERLQQEILKKDGIINEQKSNISELEQLALQLQEENNTFLDSKEEFDKLK 766

Query: 1116 STIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKI 1175
               E M  D+NN                +Q+    ++      EQ  + N   Q    KI
Sbjct: 767  EEYEKMKQDSNNPKINELEQNVKQLTKALQKTLNDLKAAKSENEQLLQSNNSDQ----KI 822

Query: 1176 IQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEI 1235
            I   +LN ++   D +NQ  IN  +   + L +EN  +     +  + IS+ ++++   +
Sbjct: 823  I---SLNKKI---DSLNQS-INDYEETTKALASENYEITQKYEQQINQISNQLNEKNVLL 875

Query: 1236 AELWKQ--HLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETN-KIVTME-Q 1291
             E  KQ   L Q   +     +E++      E +Y+Q ++ +Q  + E+ N +I+ ++ +
Sbjct: 876  QEKEKQINDLEQENKELNNQLNEMQQDKEEKEERYQQQINDLQKISNEQQNVQIIELQTE 935

Query: 1292 VTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXD 1351
               L N+L + ++     + +Y   IN +   +S    E +                   
Sbjct: 936  NKELNNQLNEMQQIKEKSEAEYQKQINDLLSNKSN-NSEMIESLRRKLQQNEEEITNYKK 994

Query: 1352 LRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLEL 1411
               E  + KQ  E+ I+N  ++  +LKK              + ND  A   +   +L  
Sbjct: 995  QINELNNTKQNNEE-IINYQKQINELKKE--------LNITKQNNDLIANYKKQIEELSK 1045

Query: 1412 KDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKE-SELAILRLKMHENA 1470
            + +E      +    L  +  + +   Q++ +Y+++I++L  EK  SE  I  L    N 
Sbjct: 1046 QSNEEVVNYQKQVEDLKNKLIDLQQNNQEIAKYQQQIDELNEEKSNSEKQINELNQKLNQ 1105

Query: 1471 NHYETMQKESEIERV-KLIEELNVKITESVSLNKQVAELNKALE---EEVA----KTNEM 1522
            N+ E  + + +IE + + +++L     E      +V +L K  +   EE+A    +  EM
Sbjct: 1106 NNEEINKYQKQIEDLNQKLKDLQENNQEIAKYQNEVDDLKKKFDVSNEEIANKEKEIEEM 1165

Query: 1523 QTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNK 1578
            +   +N   +I  LN+ +   Q+ +   +SK+   +   +  KQ  +  L++   K
Sbjct: 1166 KKKEQNYLKQISELNNHLMEKQSEIVNLNSKLDNQIYNLNTKKQNLEMNLNDLQTK 1221



 Score =  118 bits (285), Expect = 1e-24
 Identities = 202/1089 (18%), Positives = 455/1089 (41%), Gaps = 53/1089 (4%)

Query: 142  GDVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKD---QIIEAKNKATTXXXX 198
            GD+ + S + KEK+++  + Q+   + E     LQ+ +NE     Q +  +N   +    
Sbjct: 452  GDLNN-SKSQKEKESS-KLQQLNQNLSEEKAFILQQ-LNETKISMQNLMEENDHFSNELK 508

Query: 199  XXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANK 258
                         ++   Q +++Q N   +E E  D   +L  D+ +K V  SS +  + 
Sbjct: 509  QSKSLNDQNNAKIKELSDQKSQLQTNISKLEKEKSDLISKL-NDV-NKLVEQSSQKLQSN 566

Query: 259  LLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEI 318
              E  + E  L+ SK   E                     +     +E +E       E 
Sbjct: 567  NNEKLQLENELKASKSLIEQSNIKEQELNQKISQIQNQLNNSNAKIQELSENIMNLKSEN 626

Query: 319  ANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSG-RN 377
            A + E+ +K E     N  +++  +    K   + + +  + + +     L+++ S  +N
Sbjct: 627  AKLREMKQKSEENSENNINLQKIEEMNREKEELIKSYNDKIDNMTNDSIQLVNQISELKN 686

Query: 378  TASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXX 437
            T SK+++   ++ +    + +     KNE       I+ L ++++ K+ +I+E+ +    
Sbjct: 687  TISKLQNEKIEIQNRMKREVSAVTEQKNES------IERLQQEILKKDGIINEQKSNISE 740

Query: 438  XXXXXXG---KDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIK 494
                      ++      + E  +  E    +   +N   +NE+ +  +QL + L   + 
Sbjct: 741  LEQLALQLQEENNTFLDSKEEFDKLKEEYEKMKQDSNNPKINELEQNVKQLTKALQKTLN 800

Query: 495  DVNV-KDLIEKL---KSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSK- 549
            D+   K   E+L    +++++I  LN +ID+ N+++   +   K    +  +    + + 
Sbjct: 801  DLKAAKSENEQLLQSNNSDQKIISLNKKIDSLNQSINDYEETTKALASENYEITQKYEQQ 860

Query: 550  VSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLA 609
            ++  + ++      L    +++ +LE+E   L   L +    +  + + Y++ I      
Sbjct: 861  INQISNQLNEKNVLLQEKEKQINDLEQENKELNNQLNEMQQDKEEKEERYQQQINDLQKI 920

Query: 610  ETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQID 669
                + + ++E Q  +  +EL+    +  ++++K     Q Q + + S  KS +  E I+
Sbjct: 921  SNEQQNVQIIELQTEN--KELNNQLNEMQQIKEKSEAEYQKQINDLLSN-KSNN-SEMIE 976

Query: 670  ALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMN--KLQNYIQENMDLTDKLEKM 727
            +L    ++    I N K    +L  T    + + E+I+N  K  N +++ +++T +   +
Sbjct: 977  SLRRKLQQNEEEITNYKKQINELNNT----KQNNEEIINYQKQINELKKELNITKQNNDL 1032

Query: 728  SA--EKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESI 785
             A  +K  E L+K ++EE    Q Q   D K +  DL   N   E++KY+ +I  L E  
Sbjct: 1033 IANYKKQIEELSKQSNEEVVNYQKQVE-DLKNKLIDLQQNN--QEIAKYQQQIDELNEEK 1089

Query: 786  AVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIE 845
            +  E +   L +K +Q    + + QK   +   +  +L      +  +   V+    + +
Sbjct: 1090 SNSEKQINELNQKLNQNNEEINKYQKQIEDLNQKLKDLQENNQEIAKYQNEVDDLKKKFD 1149

Query: 846  HENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLES 905
              N+E+  K + + E  +  Q  L  + +  N L+EK +      S+       L   + 
Sbjct: 1150 VSNEEIANKEKEIEEMKKKEQNYLKQISELNNHLMEKQSEIVNLNSKLDNQIYNLNTKKQ 1209

Query: 906  NLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDK-KVLNEKYEKNIEYVTQLEAQL 964
            NL+   ++ QT + Q ++E  +L  + N  +E+  +++ K+  E   KN++   ++++  
Sbjct: 1210 NLEMNLNDLQTKLKQIEQENANLS-KRNKDLENESQNQAKITLETQNKNVDLTNKVKSLE 1268

Query: 965  QEYKNNIENLNMNVEELN---KMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQK 1021
            QE +  I+ L+  + +LN      LE + + V    T + + T+    E  +L   L++ 
Sbjct: 1269 QESQKLIQQLS-EITKLNANYSSELEDLREKVSSLTTSNNELTKSK-QESTELEEHLRKA 1326

Query: 1022 DEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRV--SKQLLDSKQHNE 1079
              ++   NQ + N       +V++    + +   +   +E+E Q++   K +L  +    
Sbjct: 1327 VNDLTNENQSLTNGLQETERLVAEQRKTMKEQHDQFTALEKENQQLKSEKTILQKQLEKS 1386

Query: 1080 EL----QILVREQDDQIKELKETKLTFEMNIPKTEGMI--ISSTIEPMSDDANNVDXXXX 1133
            E+    + +V+E+++ I+ LK+    +     + +  I  +   +  +    N       
Sbjct: 1387 EIAHHDEEVVKEKEETIQGLKKLLQRYVNTTKRNQQQIDDLQQQVTTLLSQQNTSVGTED 1446

Query: 1134 XXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQ 1193
                     + +E  + ++ER    + +  +  + Q+    + +     TEL        
Sbjct: 1447 SNKYLETVHRQEERIKELEERLESSQATKDIENKAQKMAKMLEKSSRQYTELLSEKEDIL 1506

Query: 1194 EQINQLKSK 1202
            +Q+NQ K K
Sbjct: 1507 KQLNQEKEK 1515



 Score =  109 bits (262), Expect = 6e-22
 Identities = 145/725 (20%), Positives = 301/725 (41%), Gaps = 55/725 (7%)

Query: 891  SESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFN------TQIESAIRDKK 944
            +E  +  +QL  L+  L    +EH  LI ++K +I ++E+E        +  +  +R+  
Sbjct: 25   TELQRICSQLFTLKEKLNNTKNEHLALIERQKNQISEMELEIQCSKSQLSSFQDLVRESV 84

Query: 945  VLNEKYEKNIEYVTQLEAQLQEYKNN------------IENLNMNVEELNKMNLELIDKH 992
               EKY+K      +LEAQ+ ++K+N             ++ N N+E L + + ++ +K 
Sbjct: 85   DEKEKYQKK---CAELEAQIADFKSNNLQSDPLNITTPSQDSNSNLEALKEKDRQIAEKE 141

Query: 993  --VQKQQTQSPDYTEQYINEINKLNALLK-QKDEEIIALNQKINNAQVSYMSMVS-DYES 1048
              +Q    +   Y++Q            K   ++E  +  +K   A ++ +   + + ++
Sbjct: 142  EIIQALSQKIQTYSDQLAATTTPSEFEAKYNAEKEAFSKFKKAAKAAIAQVQTENEELKA 201

Query: 1049 KLAQFTTKLE---NMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMN 1105
            KLA  +T  E    +E++ +   +++ +    N EL+    +   +++EL         N
Sbjct: 202  KLANASTDNEYTKQLEQQREEALQKVKELTSRNLELEAQETDFISKLEELDTELQQLRSN 261

Query: 1106 IPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLN 1165
                   +I S     S   +N D              VQ+ +  + E  +L EQ++   
Sbjct: 262  QNNNISNLIQSQNNQYSLKEDNKDSQELSSQIQNLNSMVQKLQNELSESKLLNEQNSSKI 321

Query: 1166 TELQECYTKII-QLETLNTELTGHDV-VNQEQIN-----QLKSKLEQLNTENDNLLSTVA 1218
             EL      +I +   L +EL+     V Q   N     Q  +KL++LN     L +   
Sbjct: 322  DELNALNNSLIDEKSRLESELSNAKAKVEQSNTNSSAMAQNNAKLQELNEMIQKLTNEKN 381

Query: 1219 ELRSSISSAVDQRGFEIAELWKQH--LAQREADFQKTEHELRVQLSAFESKY---EQLLD 1273
            +L   + S ++Q   ++ EL +Q+  +++ ++  QK   +   ++     K    E  ++
Sbjct: 382  QLEKDLKSQIEQDKAKLNELSQQNNKISEEKSQLQKIYEQNNTKMQELNQKLANSEAKIN 441

Query: 1274 SVQSSTQEETNKI-VTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKV 1332
             + +  Q+ +  +  +  Q     +KLQ   ++L   +      +N+ +I    + +E  
Sbjct: 442  DLNALNQKISGDLNNSKSQKEKESSKLQQLNQNLSEEKAFILQQLNETKISMQNLMEEND 501

Query: 1333 AFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXX 1392
             F                 ++  +    Q+Q  +I  + +E + L               
Sbjct: 502  HFSNELKQSKSLNDQNNAKIKELSDQKSQLQ-TNISKLEKEKSDLISKLNDVNKLVEQSS 560

Query: 1393 XRVNDAEAKVLELTHQLELKDSEIYQ---KTHEYTITLTQRNDEFENVRQQLVEYEKRIE 1449
             ++     + L+L ++L+   S I Q   K  E    ++Q  ++  N   ++ E  + I 
Sbjct: 561  QKLQSNNNEKLQLENELKASKSLIEQSNIKEQELNQKISQIQNQLNNSNAKIQELSENIM 620

Query: 1450 DLTYEKESELAILRLKMHENANHYETMQKESEIERVK--LIEELNVKI----TESVSLNK 1503
            +L  E  ++L  ++ K  EN+ +   +QK  E+ R K  LI+  N KI     +S+ L  
Sbjct: 621  NLKSE-NAKLREMKQKSEENSENNINLQKIEEMNREKEELIKSYNDKIDNMTNDSIQLVN 679

Query: 1504 QVAELNKALEEEVAKTNEMQTALENQEIEIVT--LNDEITNLQNMVRASSSKIQKHVSFA 1561
            Q++EL   + +   +  E+Q  ++ +E+  VT   N+ I  LQ  +      I +  S  
Sbjct: 680  QISELKNTISKLQNEKIEIQNRMK-REVSAVTEQKNESIERLQQEILKKDGIINEQKSNI 738

Query: 1562 SDTKQ 1566
            S+ +Q
Sbjct: 739  SELEQ 743



 Score = 58.8 bits (136), Expect = 1e-06
 Identities = 86/435 (19%), Positives = 186/435 (42%), Gaps = 35/435 (8%)

Query: 1149 EFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNT 1208
            E + E+   Q++ A+L  ++ +  +  +Q + LN      D  +   +  LK K  Q+  
Sbjct: 82   ESVDEKEKYQKKCAELEAQIADFKSNNLQSDPLNITTPSQD--SNSNLEALKEKDRQI-A 138

Query: 1209 ENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKY 1268
            E + ++  +++   + S  +       +E   ++ A++EA F K +   +  ++  +++ 
Sbjct: 139  EKEEIIQALSQKIQTYSDQLAATTTP-SEFEAKYNAEKEA-FSKFKKAAKAAIAQVQTEN 196

Query: 1269 EQLLDSV-QSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEI 1327
            E+L   +  +ST  E  K +  ++  +LQ K+++       L+ +  D I+++E L +E+
Sbjct: 197  EELKAKLANASTDNEYTKQLEQQREEALQ-KVKELTSRNLELEAQETDFISKLEELDTEL 255

Query: 1328 EDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXX 1387
            +  + +                  L+ +N+  +++  Q I N+N    +L+         
Sbjct: 256  QQLR-SNQNNNISNLIQSQNNQYSLKEDNKDSQELSSQ-IQNLNSMVQKLQNELSESKLL 313

Query: 1388 XXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKR 1447
                  ++++  A    L  +    +SE+     +   + T  +   +N   +L E  + 
Sbjct: 314  NEQNSSKIDELNALNNSLIDEKSRLESELSNAKAKVEQSNTNSSAMAQN-NAKLQELNEM 372

Query: 1448 IEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAE 1507
            I+ LT EK               N  E   K S+IE+ K   +LN    ++  ++++ ++
Sbjct: 373  IQKLTNEK---------------NQLEKDLK-SQIEQDKA--KLNELSQQNNKISEEKSQ 414

Query: 1508 LNKALEEEVAKTNEMQTALENQEIEIVTLN-------DEITNLQNMVRASSSKIQKHVSF 1560
            L K  E+   K  E+   L N E +I  LN        ++ N ++     SSK+Q+    
Sbjct: 415  LQKIYEQNNTKMQELNQKLANSEAKINDLNALNQKISGDLNNSKSQKEKESSKLQQLNQN 474

Query: 1561 ASDTKQGRDEQLDNT 1575
             S+ K    +QL+ T
Sbjct: 475  LSEEKAFILQQLNET 489


>UniRef50_A2ETW9 Cluster: Viral A-type inclusion protein, putative;
            n=1; Trichomonas vaginalis G3|Rep: Viral A-type inclusion
            protein, putative - Trichomonas vaginalis G3
          Length = 2010

 Score =  177 bits (431), Expect = 2e-42
 Identities = 297/1410 (21%), Positives = 613/1410 (43%), Gaps = 125/1410 (8%)

Query: 215  KQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKL 274
            KQQ+ K+Q +      +    + RL K  E     IS+L+  N  L+    ++SL  SK+
Sbjct: 236  KQQLIKLQNDLDEERVKSVATEDRLTKFREESSKAISTLKSQNSNLQE---QLSL--SKI 290

Query: 275  AQELEQXXXXXXXXXXXXXXLAKQS-IEPSCEEKTEIEEKGSLEIANMTELTKK----IE 329
             Q   Q                K + I+   +E +  EE+ +   A +TEL K     I+
Sbjct: 291  EQNSAQNAGNDELLKIKSEIDDKNNEIKNLQQEISNFEEENANLNAKITELEKSAKKSIQ 350

Query: 330  LLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQL 389
             +  L  +I   ++ELE +  T  TES   S   +K    +      N   +++   +QL
Sbjct: 351  TISILEKEIDDLSEELEKQQVTK-TESN--SDDFQKQVEAVRLVKEEN--DQLRDQINQL 405

Query: 390  SSETLNQDTDKKINKNEIAKLEMVIQSLNKDLV--DKEYVISEKDTXXXXXXXXXXGKDT 447
            +     +  +  + +N+  K E +       L+  + E ++ E +            +  
Sbjct: 406  T--VYKEKMNSILKENQNLKSEYIKMKDENTLLREENERIMEESNAAKENLKKENENQKN 463

Query: 448  LIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDL-IEKLK 506
             I+ L  E +       L  +    + + +  + Q ++ Q+LN+E+  +  K+   +KL 
Sbjct: 464  EISSLTNEDE-------LYKLREENDKLIKSREAQNEIIQKLNNEMNQMKEKEKDFDKLA 516

Query: 507  SAEEQITQLNDE-IDAANKNMIKVKSNHKLKLKQMQKTI----DNFSKVSDSNKEIVRLT 561
              ++ +   ND  I++  + + K K  ++    ++Q+      +N +K ++  +   +L 
Sbjct: 517  QEKKLLKDENDRLINSEMEELDKYKKENQDLNNELQRIKNERQENENKENNLKQGNEQLN 576

Query: 562  EELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLES 621
            EEL    Q V   EEE   ++    + D  R    ++ +K     N  E   K I   E 
Sbjct: 577  EELQRTKQTVINKEEELKKVR---DEADKLRKKIEELKEKQQNQINDNEELRKEIKSSEE 633

Query: 622  QKFDLVQELHILQQKYDEVEDKLADISQ-LQSDQVCSEIK-SVHLEEQIDALSASKKELA 679
            +  ++  E  IL+++ ++ ++  ++IS  LQ     S +K S+     ++ +   KKE  
Sbjct: 634  KMKEIQSENEILKKQIEKEDENSSNISDDLQKLVNKSLVKESIDENNDVETIENLKKE-- 691

Query: 680  LVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQ---ENMDLTDKLEKMSAE--KISE 734
              IE+LK +K+  + +I  +EN  ED+ ++++  I+   E   ++++LEK+ A   ++  
Sbjct: 692  --IEDLKKEKDN-FDSIS-IEN--EDLRSQVEVLIKVEDERNQMSEELEKLRANYNELQS 745

Query: 735  LLAKINHEEQSK-IQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRY 793
             ++K N E   + I+   G  +K+QE    +E+I++EL   +      E   +    +  
Sbjct: 746  QISKQNFENNKETIEKLIGEKSKLQEE---LESIKNELDSIQVEKIESENESS---SKII 799

Query: 794  SLERKADQLGSYLQE--KQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKEL 851
            +L  + D+L + +    +QK+  E+TI E +  N            E ++ +++ EN++L
Sbjct: 800  ALTEEIDELKNQINNISEQKSTLEFTIDEIKAQN------------ESEISQLKKENEDL 847

Query: 852  QKKNQILLEENQNLQISLSDMQQ-HYNALVEKANRTDLAESESTKYQTQLRDLESNLKRI 910
              K + L +EN  L+  + ++Q  H  +L+E      L  +   +    L++   N+KR 
Sbjct: 848  NSKIESLSKENNELKTEIENIQNSHSLSLLETEMNNKL--TNLNEENDMLKNENENIKR- 904

Query: 911  THEHQTLIVQKK-KEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKN 969
              + +TL   K  K+  D   +  T+I    +DK    E+ +K    V  L  +  E K+
Sbjct: 905  -EKEETLAENKSLKDTLDFFEKNLTKINEQNKDK---TEELDKQKRIVLTLTGENNELKS 960

Query: 970  NIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALN 1029
             ++ +  + E L K N +L       Q     +     +  + + N  LK++ E++ A N
Sbjct: 961  KLDKIKNDYELLQKENEKLESDIDNPQNLSLLEEMNSKLTALTEENKKLKEEIEDLQAEN 1020

Query: 1030 QKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNE---ELQILVR 1086
            + + N   S   + ++  SKL   T +   +++E +++   L ++    E   +L  L  
Sbjct: 1021 EALQNTH-SLSLLETEMNSKLTSLTEENGKLKKENEKLKIDLQNNSIEKELKLKLTKLTE 1079

Query: 1087 EQDDQIKELKETK-LTFEMNIPKTEGMI---ISSTIEPMSDDANNVDXXXXXXXXXXXXL 1142
            E +   KE KE K +  +MN   +  ++   +++ +  +S++ N +              
Sbjct: 1080 ENEKLGKESKELKQIIDQMNDTHSLSLLETEMNNKLASLSEENNKLKEENNKLTKSNEKA 1139

Query: 1143 KVQEE------EEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTEL----------T 1186
            K + +      +E+  +   ++++   L+ E Q  ++KI  L   N E+          +
Sbjct: 1140 KTEYQSLKTIVDEYGNDYEEMKQKIEDLSFENQNMHSKIEFLTQENKEMKDEIAKLNQNS 1199

Query: 1187 GHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQR 1246
            G D  N++++ +L+ + E L  EN NL   + +++S +++   +   EI +     L  +
Sbjct: 1200 GDDDYNKQEVIELRDENESLIHENSNLKLEIEKMKSKLTTFSPKEKVEILQQEIAQLTSK 1259

Query: 1247 EADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHL 1306
              + ++  ++L+   S+F S Y  LL + Q  T ++  K++    V S  NK  + +E+L
Sbjct: 1260 NKELEEEINQLKNNNSSFLS-YSSLLKTPQPQTSKKGIKLINTTSVLS-TNK-NESDENL 1316

Query: 1307 RNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQS 1366
             NL E     I  +      +  E +                  +L+ +N+  +   +  
Sbjct: 1317 ENLNESLLQTIENLRHENDNLTQENIKLKSQKSLKLLQDIKSQLELK-DNEINE--LKSK 1373

Query: 1367 ILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEA-KVLELTHQLELKDSEIYQKTHEYTI 1425
            I +++E+N Q+ K +            +  + E  K+LE   + EL+  +I  +      
Sbjct: 1374 INDLSEKNEQITKINESLQLRSSPTKTKSLELERDKLLERAAKAELELEDIKSRLD---- 1429

Query: 1426 TLTQRNDEFE---NVRQ-QLVEYEK-RIEDLTYEKESELAILRLKMHENANHYETMQKES 1480
            +L + ND  +   + R+ + VE E+  +   T + E +L   + K+++       +++  
Sbjct: 1430 SLAKENDTLKLRPSPRKVKSVEAERDNLLARTTKAELDLEDAKTKINDLTKENNILKQRP 1489

Query: 1481 EIERVKLIE-ELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDE 1539
               + K I+ E +  +  +    KQ+ E+ + + E      E+ + L N + EI  + + 
Sbjct: 1490 SPTKTKHIQIERDHLLDRATKAEKQLEEMKENISELSIAKEELDSQLANCQKEINRMTEV 1549

Query: 1540 ITNLQ---NMVRASSSKIQKHVSFASDTKQ 1566
              NL+   N +   S  + K +S A D K+
Sbjct: 1550 DENLKKKLNDMDIISDAVSK-ISRAKDQKE 1578



 Score =  165 bits (400), Expect = 1e-38
 Identities = 316/1517 (20%), Positives = 642/1517 (42%), Gaps = 178/1517 (11%)

Query: 143  DVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXX 202
            ++  + + I +K+N +  LQ ++   E    +L  KI E ++   AK    T        
Sbjct: 302  ELLKIKSEIDDKNNEIKNLQQEISNFEEENANLNAKITELEK--SAKKSIQTISILEKEI 359

Query: 203  XXXXXXXXXEDTKQQMTKMQENFIAMEAEW------KDEKQRLLKDIESKDV---RISSL 253
                     E  KQQ+TK + N    + +       K+E  +L   I    V   +++S+
Sbjct: 360  DDLSE----ELEKQQVTKTESNSDDFQKQVEAVRLVKEENDQLRDQINQLTVYKEKMNSI 415

Query: 254  EEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCE-EKTEIEE 312
             + N+ L++   ++  E++ L +E E+               AK++++   E +K EI  
Sbjct: 416  LKENQNLKSEYIKMKDENTLLREENERIMEESNA--------AKENLKKENENQKNEISS 467

Query: 313  -KGSLEIANMTELTKKI--------ELLEHLNCQIRQTNKELENKLATMGTESKAVSSPS 363
                 E+  + E   K+        E+++ LN ++ Q  KE E     +  E K +   +
Sbjct: 468  LTNEDELYKLREENDKLIKSREAQNEIIQKLNNEMNQM-KEKEKDFDKLAQEKKLLKDEN 526

Query: 364  KKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVD 423
             +   LI+  S      K K     L++E      +++ N+N+   L+   + LN++L  
Sbjct: 527  DR---LIN--SEMEELDKYKKENQDLNNELQRIKNERQENENKENNLKQGNEQLNEELQR 581

Query: 424  KEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIH--VGTNTEDVNEIAKV 481
             +  +  K+                I +L+ + Q  +     +   + ++ E + EI   
Sbjct: 582  TKQTVINKEEELKKVRDEADKLRKKIEELKEKQQNQINDNEELRKEIKSSEEKMKEIQSE 641

Query: 482  QEQLKQELNDEIKDV-NVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQM 540
             E LK+++  E ++  N+ D ++KL +     + + + ID    N ++   N K +++ +
Sbjct: 642  NEILKKQIEKEDENSSNISDDLQKLVNK----SLVKESID--ENNDVETIENLKKEIEDL 695

Query: 541  QKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYK 600
            +K  DNF  +S  N+++    E L  +  +  ++ EE   L+    +Y+    ++S + K
Sbjct: 696  KKEKDNFDSISIENEDLRSQVEVLIKVEDERNQMSEELEKLR---ANYNE---LQSQISK 749

Query: 601  KMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIK 660
            +    EN  ET    I  L  +K  L +EL  ++ + D ++     + +++S+   S  K
Sbjct: 750  Q--NFENNKET----IEKLIGEKSKLQEELESIKNELDSIQ-----VEKIESENESSS-K 797

Query: 661  SVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDL 720
             + L E+ID       EL   I N+   K  L  TI +++   E  +++L+   +EN DL
Sbjct: 798  IIALTEEID-------ELKNQINNISEQKSTLEFTIDEIKAQNESEISQLK---KENEDL 847

Query: 721  TDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICR 780
              K+E +S E  +EL  +I + + S   +    +   +  +L   N E+++ K ++   +
Sbjct: 848  NSKIESLSKEN-NELKTEIENIQNSHSLSLLETEMNNKLTNL---NEENDMLKNENENIK 903

Query: 781  LEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQ 840
             E+   + E++  SL+   D     L +  +   + T + D+    +  L   +  ++ +
Sbjct: 904  REKEETLAENK--SLKDTLDFFEKNLTKINEQNKDKTEELDKQKRIVLTLTGENNELKSK 961

Query: 841  LLEIEHENKELQKKNQIL---LEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQ 897
            L +I+++ + LQK+N+ L   ++  QNL + L +M     AL E          E+ K +
Sbjct: 962  LDKIKNDYELLQKENEKLESDIDNPQNLSL-LEEMNSKLTALTE----------ENKKLK 1010

Query: 898  TQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYV 957
             ++ DL++  + + + H   +         LE E N+++ S   +   L ++ EK ++  
Sbjct: 1011 EEIEDLQAENEALQNTHSLSL---------LETEMNSKLTSLTEENGKLKKENEK-LKID 1060

Query: 958  TQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINE----INK 1013
             Q  +  +E K  +  L    E+L K + EL     Q   T S    E  +N     +++
Sbjct: 1061 LQNNSIEKELKLKLTKLTEENEKLGKESKELKQIIDQMNDTHSLSLLETEMNNKLASLSE 1120

Query: 1014 LNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLD 1073
             N  LK+++ ++   N+K      S  ++V +Y +   +   K+E++  E Q +  ++  
Sbjct: 1121 ENNKLKEENNKLTKSNEKAKTEYQSLKTIVDEYGNDYEEMKQKIEDLSFENQNMHSKIEF 1180

Query: 1074 SKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXX 1133
              Q N+E++       D+I +L +     + N  K E + +    E +  + +N+     
Sbjct: 1181 LTQENKEMK-------DEIAKLNQNSGDDDYN--KQEVIELRDENESLIHENSNLKLEIE 1231

Query: 1134 XXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQ 1193
                       +E+ E      +LQ++ A+L ++ +E   +I QL+  N+    +  +  
Sbjct: 1232 KMKSKLTTFSPKEKVE------ILQQEIAQLTSKNKELEEEINQLKNNNSSFLSYSSL-- 1283

Query: 1194 EQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQ-READFQK 1252
                 LK+   Q + +   L++T + L ++ + + D+    + E   Q +   R  +   
Sbjct: 1284 -----LKTPQPQTSKKGIKLINTTSVLSTNKNES-DENLENLNESLLQTIENLRHENDNL 1337

Query: 1253 TEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEK 1312
            T+  ++++      K  +LL  ++S  + + N+I    ++ S  N L +K E +  + E 
Sbjct: 1338 TQENIKLK----SQKSLKLLQDIKSQLELKDNEI---NELKSKINDLSEKNEQITKINES 1390

Query: 1313 YADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXD-LRTENQSYK-QMQEQSILNI 1370
                 +  +    E+E +K+                  D L  EN + K +   + + ++
Sbjct: 1391 LQLRSSPTKTKSLELERDKLLERAAKAELELEDIKSRLDSLAKENDTLKLRPSPRKVKSV 1450

Query: 1371 NEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLE-LKDSEIYQKTHEYTITLTQ 1429
              E   L   +             + DA+ K+ +LT +   LK      KT    I    
Sbjct: 1451 EAERDNLLARTTKAELD-------LEDAKTKINDLTKENNILKQRPSPTKTKHIQIERDH 1503

Query: 1430 RNDEFENVRQQLVEYEKRIEDLTYEKE---SELAILRLKMHENANHYETMQKE------- 1479
              D      +QL E ++ I +L+  KE   S+LA  + +++      E ++K+       
Sbjct: 1504 LLDRATKAEKQLEEMKENISELSIAKEELDSQLANCQKEINRMTEVDENLKKKLNDMDII 1563

Query: 1480 ----SEIERVKLIEELNVKITESVSLNKQVAELNKALEEEV---------AKT-NEMQTA 1525
                S+I R K  +ELN KI E    N+++   N  L EE+         +KT  E +  
Sbjct: 1564 SDAVSKISRAKDQKELNTKIEELQKENQKLQTKNAELAEEINSSKFSPRQSKTIQEFRQK 1623

Query: 1526 LENQEIEIVTLNDEITNLQ---NMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLD 1582
             E    E   LN  I+ L+   N    S+   ++ +S   +      +Q+ +  N++   
Sbjct: 1624 FEEISKENEKLNKRISELEFERNSNNTSTKINRQKISELENINFSMQKQIVSLENEKKFT 1683

Query: 1583 AVPRAELDLAMYMLHQR 1599
                AEL+    +L+ R
Sbjct: 1684 KNKIAELENEKLILNNR 1700



 Score =  149 bits (361), Expect = 6e-34
 Identities = 243/1134 (21%), Positives = 498/1134 (43%), Gaps = 101/1134 (8%)

Query: 496  VNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNK 555
            +N  DLIEKL+ A ++  +L  EI+  ++    +++    K+ Q    + N  K SD N 
Sbjct: 119  LNHNDLIEKLEIASKENDELRKEIEGFHELSRSLQNQLDEKINQCDALV-NEKKSSDKN- 176

Query: 556  EIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKA 615
             I +L +++  L  +  +LE  +   Q+ + + +  ++  +D +    +  N + +    
Sbjct: 177  -IDQLKKQIEQLKSQF-KLETSRYEKQIDVYELELAKL--ADEHNNKNDQSNTSNSE-SE 231

Query: 616  ISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKS--VHLEEQIDALSA 673
            I+ L+ Q   L  +L   + K    ED+L    + +S +  S +KS   +L+EQ+ +LS 
Sbjct: 232  INKLKQQLIKLQNDLDEERVKSVATEDRLTKFRE-ESSKAISTLKSQNSNLQEQL-SLSK 289

Query: 674  SKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKM--SAEK 731
             ++  A    N +L K  +   I D  N+ +++  ++ N+ +EN +L  K+ ++  SA+K
Sbjct: 290  IEQNSAQNAGNDELLK--IKSEIDDKNNEIKNLQQEISNFEEENANLNAKITELEKSAKK 347

Query: 732  ISELLAKINHEEQSKIQTQFGIDAKIQERDL-YIENIESELSKYKSRICRLEESIAVMED 790
              + ++ +  E          +  +++++ +   E+   +  K    +  ++E    + D
Sbjct: 348  SIQTISILEKEIDD-------LSEELEKQQVTKTESNSDDFQKQVEAVRLVKEENDQLRD 400

Query: 791  RRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVE-----KQLLEIE 845
            +   L    +++ S L+E Q   SEY   +DE  N L +  +++R++E     K+ L+ E
Sbjct: 401  QINQLTVYKEKMNSILKENQNLKSEYIKMKDE--NTL-LREENERIMEESNAAKENLKKE 457

Query: 846  HENKE-----LQKKNQI--LLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQT 898
            +EN++     L  ++++  L EEN  L  S     +    L  + N+    E +  K   
Sbjct: 458  NENQKNEISSLTNEDELYKLREENDKLIKSREAQNEIIQKLNNEMNQMKEKEKDFDKLAQ 517

Query: 899  QLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVT 958
            + + L+    R+ +     + + KKE +DL    N +++  I++++  NE  E N++   
Sbjct: 518  EKKLLKDENDRLINSEMEELDKYKKENQDL----NNELQ-RIKNERQENENKENNLKQGN 572

Query: 959  -QLEAQLQEYK----NNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINK 1013
             QL  +LQ  K    N  E L    +E +K+  + I++  +KQQ Q  D  E+   EI  
Sbjct: 573  EQLNEELQRTKQTVINKEEELKKVRDEADKLR-KKIEELKEKQQNQIND-NEELRKEIKS 630

Query: 1014 LNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEE-----MQRVS 1068
                +K+   E   L ++I     +  S +SD   KL   +   E+++E      ++ + 
Sbjct: 631  SEEKMKEIQSENEILKKQIEKEDEN-SSNISDDLQKLVNKSLVKESIDENNDVETIENLK 689

Query: 1069 KQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNV 1128
            K++ D K+  +    +  E +D ++   E  +  E      E   +S  +E +  + N +
Sbjct: 690  KEIEDLKKEKDNFDSISIENED-LRSQVEVLIKVE-----DERNQMSEELEKLRANYNEL 743

Query: 1129 DXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGH 1188
                           +   E+ I E+S LQE+   +  EL     + I+ E    E +  
Sbjct: 744  QSQISKQNFENNKETI---EKLIGEKSKLQEELESIKNELDSIQVEKIESE---NESSSK 797

Query: 1189 DVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAEL-WKQHLAQRE 1247
             +   E+I++LK+++  ++ +   L  T+ E+++   S + Q   E  +L  K     +E
Sbjct: 798  IIALTEEIDELKNQINNISEQKSTLEFTIDEIKAQNESEISQLKKENEDLNSKIESLSKE 857

Query: 1248 ADFQKTEHELRVQ----LSAFESKYEQLLDSVQSST---QEETNKIVTMEQVTSLQNK-L 1299
             +  KTE E  +Q    LS  E++    L ++       + E   I   ++ T  +NK L
Sbjct: 858  NNELKTEIE-NIQNSHSLSLLETEMNNKLTNLNEENDMLKNENENIKREKEETLAENKSL 916

Query: 1300 QDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSY 1359
            +D  +      EK    IN+    ++E  D++                    ++ + +  
Sbjct: 917  KDTLDFF----EKNLTKINEQNKDKTEELDKQKRIVLTLTGENNELKSKLDKIKNDYELL 972

Query: 1360 KQMQEQSILNI-NEENAQLKKSSXXXXXXXXXXXXRVND------AEAKVLELTHQLELK 1412
            ++  E+   +I N +N  L +              ++ +      AE + L+ TH L L 
Sbjct: 973  QKENEKLESDIDNPQNLSLLEEMNSKLTALTEENKKLKEEIEDLQAENEALQNTHSLSLL 1032

Query: 1413 DSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANH 1472
            ++E+  K      +LT+ N + +   ++L   +  +++ + EKE +L + +L        
Sbjct: 1033 ETEMNSK----LTSLTEENGKLKKENEKL---KIDLQNNSIEKELKLKLTKLTEENEKLG 1085

Query: 1473 YETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIE 1532
             E+ + +  I+++     L++  TE  +    ++E N  L+EE    N++  + E  + E
Sbjct: 1086 KESKELKQIIDQMNDTHSLSLLETEMNNKLASLSEENNKLKEE---NNKLTKSNEKAKTE 1142

Query: 1533 IVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPR 1586
              +L   +    N       KI+  +SF +     + E L    NKE+ D + +
Sbjct: 1143 YQSLKTIVDEYGNDYEEMKQKIE-DLSFENQNMHSKIEFLTQE-NKEMKDEIAK 1194



 Score =  136 bits (329), Expect = 5e-30
 Identities = 297/1509 (19%), Positives = 622/1509 (41%), Gaps = 139/1509 (9%)

Query: 96   NTLKQKEILMEKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKD 155
            N +K+KE   +K+ Q K+L K  +  ++                   ++  + N  +E +
Sbjct: 503  NQMKEKEKDFDKLAQEKKLLKDENDRLINSEMEELDKYKKENQDLNNELQRIKNERQENE 562

Query: 156  NALSVL-QVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDT 214
            N  + L Q   ++ E      Q  IN+++++ + +++A                   ++ 
Sbjct: 563  NKENNLKQGNEQLNEELQRTKQTVINKEEELKKVRDEADKLRKKIEELKEKQQNQINDN- 621

Query: 215  KQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSL-EEANKLLEAARFEISLEHSK 273
             +++ K  ++      E + E + L K IE +D   S++ ++  KL+  +  + S++ + 
Sbjct: 622  -EELRKEIKSSEEKMKEIQSENEILKKQIEKEDENSSNISDDLQKLVNKSLVKESIDENN 680

Query: 274  LAQELEQXXXXXXXXXXXXXXLAKQSIE-PSCEEKTEIEEKGSLEIANMTELTKKIEL-L 331
              + +E                   SIE      + E+  K   E   M+E  +K+    
Sbjct: 681  DVETIENLKKEIEDLKKEKDNFDSISIENEDLRSQVEVLIKVEDERNQMSEELEKLRANY 740

Query: 332  EHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSS 391
              L  QI + N   EN   T+    K +   SK    L S K+  ++    K      SS
Sbjct: 741  NELQSQISKQN--FENNKETI---EKLIGEKSKLQEELESIKNELDSIQVEKIESENESS 795

Query: 392  E---TLNQDTDKKINK-NEIAKLEMVIQ-SLNKDLVDKEYVISE--KDTXXXXXXXXXXG 444
                 L ++ D+  N+ N I++ +  ++ ++++     E  IS+  K+            
Sbjct: 796  SKIIALTEEIDELKNQINNISEQKSTLEFTIDEIKAQNESEISQLKKENEDLNSKIESLS 855

Query: 445  KDTLIAQLQLEHQQHMEGPSLIHVG-----TNTEDVNEIAKVQ-EQLKQEL------NDE 492
            K+    + ++E+ Q+    SL+        TN  + N++ K + E +K+E       N  
Sbjct: 856  KENNELKTEIENIQNSHSLSLLETEMNNKLTNLNEENDMLKNENENIKREKEETLAENKS 915

Query: 493  IKDV------NV-------KDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQ 539
            +KD       N+       KD  E+L   +  +  L  E +     + K+K++++L  K+
Sbjct: 916  LKDTLDFFEKNLTKINEQNKDKTEELDKQKRIVLTLTGENNELKSKLDKIKNDYELLQKE 975

Query: 540  MQKT---IDN---FSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQ----LHLVDYD 589
             +K    IDN    S + + N ++  LTEE   L +++ +L+ E   LQ    L L++ +
Sbjct: 976  NEKLESDIDNPQNLSLLEEMNSKLTALTEENKKLKEEIEDLQAENEALQNTHSLSLLETE 1035

Query: 590  SGRMIES----------DVYKKMIEMENLA---ETRLKAISLLESQKFDLVQELHILQQK 636
                + S          +  K  I+++N +   E +LK   L E  +  L +E   L+Q 
Sbjct: 1036 MNSKLTSLTEENGKLKKENEKLKIDLQNNSIEKELKLKLTKLTEENE-KLGKESKELKQI 1094

Query: 637  YDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTI 696
             D++ D  + +S L+++      K   L E+ + L     +L    E  K + + L   +
Sbjct: 1095 IDQMNDTHS-LSLLETEM---NNKLASLSEENNKLKEENNKLTKSNEKAKTEYQSLKTIV 1150

Query: 697  KDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAE--KISELLAKIN-------HEEQSKI 747
             +  ND E++  K+++   EN ++  K+E ++ E  ++ + +AK+N       + +Q  I
Sbjct: 1151 DEYGNDYEEMKQKIEDLSFENQNMHSKIEFLTQENKEMKDEIAKLNQNSGDDDYNKQEVI 1210

Query: 748  QTQFGIDAKIQERD---LYIENIESELSKY--KSRICRLEESIAVMEDRRYSLERKADQL 802
            + +   ++ I E     L IE ++S+L+ +  K ++  L++ IA +  +   LE + +QL
Sbjct: 1211 ELRDENESLIHENSNLKLEIEKMKSKLTTFSPKEKVEILQQEIAQLTSKNKELEEEINQL 1270

Query: 803  ----GSYLQEKQ--KAYSEYTIQED-ELVNRLAVLM----DHDRVVEK------QLLE-I 844
                 S+L      K     T ++  +L+N  +VL     + D  +E       Q +E +
Sbjct: 1271 KNNNSSFLSYSSLLKTPQPQTSKKGIKLINTTSVLSTNKNESDENLENLNESLLQTIENL 1330

Query: 845  EHENKELQKKN-----QILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQT- 898
             HEN  L ++N     Q  L+  Q+++  L       N L  K N       + TK    
Sbjct: 1331 RHENDNLTQENIKLKSQKSLKLLQDIKSQLELKDNEINELKSKINDLSEKNEQITKINES 1390

Query: 899  -QLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYV 957
             QLR   +  K +  E   L+ +  K   +LE +  ++++S  ++   L  K   +   V
Sbjct: 1391 LQLRSSPTKTKSLELERDKLLERAAKAELELE-DIKSRLDSLAKENDTL--KLRPSPRKV 1447

Query: 958  TQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNAL 1017
              +EA+            +++E+      +L  ++   +Q  SP  T+    E + L   
Sbjct: 1448 KSVEAERDNLLARTTKAELDLEDAKTKINDLTKENNILKQRPSPTKTKHIQIERDHLLDR 1507

Query: 1018 LKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQH 1077
              + ++++  + + I+   ++      + +S+LA    ++  M E  + + K+L D    
Sbjct: 1508 ATKAEKQLEEMKENISELSIAK----EELDSQLANCQKEINRMTEVDENLKKKLNDMDII 1563

Query: 1078 NEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXX 1137
            ++ +  + R +D +    K  +L  E    +T+   ++   E ++    +          
Sbjct: 1564 SDAVSKISRAKDQKELNTKIEELQKENQKLQTKNAELA---EEINSSKFSPRQSKTIQEF 1620

Query: 1138 XXXXLKVQEEEEFIQER-SVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQI 1196
                 ++ +E E + +R S L+ +    NT  +    KI +LE +N  +    V  + + 
Sbjct: 1621 RQKFEEISKENEKLNKRISELEFERNSNNTSTKINRQKISELENINFSMQKQIVSLENEK 1680

Query: 1197 NQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHE 1256
               K+K+ +L  EN+ L+     L + I S +  +     E+  + ++Q     + T  +
Sbjct: 1681 KFTKNKIAEL--ENEKLI-----LNNRIDSLISNKSSPENEI--RQMSQTIEGLKNTITD 1731

Query: 1257 LRVQLSAFESKYEQLLDSVQSSTQEETNKIVTM-EQVTSLQNKLQDKEEHLRNLQEKYAD 1315
            L  Q+   + + + L +S      EE+ +   + E++  L+ +L   +  L N   K +D
Sbjct: 1732 LTKQIRKLQKENDTLRESSMMIAGEESKEETKLKEEIAELKFRLSQMQSELINANSKLSD 1791

Query: 1316 VINQIEILRSEIEDE--KVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEE 1373
             I+      S   DE  K                     + +NQ+ K +Q+        E
Sbjct: 1792 AISSDRQNFSNNTDEVTKANENKIKSLNTKLKKLSEEKKKLQNQNNKLLQDLEKFRSEYE 1851

Query: 1374 NAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDE 1433
            N +                  + +   ++ + +  L  + +E+ Q + +   TL ++   
Sbjct: 1852 NIRSFIDQKGDKEQKDEEYTLLQEKYIQLQKESISLNSQLNEL-QSSRKTIRTLQRKLKS 1910

Query: 1434 FENVRQQLVEYEKRIEDLTYEKESELAILRLK----MHENANHYETMQKESEIERVKLIE 1489
             EN    ++E ++        ++ +  +L LK     ++ A+   + Q  S+ + +KL+ 
Sbjct: 1911 LENNANSIMETDRHCHCSEALEQFKQEVLELKEIILKNDEASSKISKQISSQSDEIKLL- 1969

Query: 1490 ELNVKITES 1498
             ++ K+T+S
Sbjct: 1970 RIHSKVTDS 1978



 Score = 70.1 bits (164), Expect = 5e-10
 Identities = 133/665 (20%), Positives = 283/665 (42%), Gaps = 67/665 (10%)

Query: 957  VTQLEAQLQEYKNNIENLNM-NVEELNKMNLELIDKH-------VQKQQTQSPDYTEQYI 1008
            VT+L+ QL  YK  I++L + N EE+ ++  ++I K+       + K  T S + +    
Sbjct: 41   VTELQNQLFNYKMKIDDLRIHNNEEIIRLK-KIIAKYEGPSNEILTKNSTSSSNSSLSPN 99

Query: 1009 NEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESK----LAQFTTKLENMEEEM 1064
            +   + N      D     LN      ++   S  +D   K      + +  L+N  +E 
Sbjct: 100  SPSREGNLARSLIDSSSSFLNHNDLIEKLEIASKENDELRKEIEGFHELSRSLQNQLDEK 159

Query: 1065 QRVSKQLLDSKQHNEELQILVREQDDQIK---ELKETKLTFEMNIPKTEGMIISSTIEPM 1121
                  L++ K+ +++    +++Q +Q+K   +L+ ++   ++++ + E   ++      
Sbjct: 160  INQCDALVNEKKSSDKNIDQLKKQIEQLKSQFKLETSRYEKQIDVYELELAKLADEHNNK 219

Query: 1122 SDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETL 1181
            +D +N  +            +K+Q + +  + +SV  E   +L    +E    I  L++ 
Sbjct: 220  NDQSNTSNSESEINKLKQQLIKLQNDLDEERVKSVATED--RLTKFREESSKAISTLKSQ 277

Query: 1182 NTELTGHDVVNQEQINQLKSKLEQ---LNTENDNLLSTVAELRSSISSAVD-QRGFEIAE 1237
            N+ L       QEQ++   SK+EQ    N  ND LL   +E+    +   + Q+     E
Sbjct: 278  NSNL-------QEQLS--LSKIEQNSAQNAGNDELLKIKSEIDDKNNEIKNLQQEISNFE 328

Query: 1238 LWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSV--QSSTQEETNKIVTMEQVTSL 1295
                +L  +  + +K+  +    +S  E + + L + +  Q  T+ E+N     +QV ++
Sbjct: 329  EENANLNAKITELEKSAKKSIQTISILEKEIDDLSEELEKQQVTKTESNSDDFQKQVEAV 388

Query: 1296 Q------NKLQDKEEHLRNLQEKYADVINQIEILRSE---IEDEKVAFXXXXXXXXXXXX 1346
            +      ++L+D+   L   +EK   ++ + + L+SE   ++DE                
Sbjct: 389  RLVKEENDQLRDQINQLTVYKEKMNSILKENQNLKSEYIKMKDENTLLREENERIMEESN 448

Query: 1347 XXXXDLRTENQSYKQ-----MQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAK 1401
                +L+ EN++ K        E  +  + EEN +L KS               N+   K
Sbjct: 449  AAKENLKKENENQKNEISSLTNEDELYKLREENDKLIKSREAQ-----------NEIIQK 497

Query: 1402 VLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVR-QQLVEYEKRIEDLTYEKESELA 1460
            +    +Q++ K+ + + K  +    L   ND   N   ++L +Y+K  +DL     +EL 
Sbjct: 498  LNNEMNQMKEKEKD-FDKLAQEKKLLKDENDRLINSEMEELDKYKKENQDL----NNELQ 552

Query: 1461 ILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEE-EVAKT 1519
             ++ +  EN N    +++ +E    +L       I +   L K   E +K  ++ E  K 
Sbjct: 553  RIKNERQENENKENNLKQGNEQLNEELQRTKQTVINKEEELKKVRDEADKLRKKIEELKE 612

Query: 1520 NEMQTALENQEI--EIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMN 1577
             +     +N+E+  EI +  +++  +Q+       +I+K    +S+      + ++ ++ 
Sbjct: 613  KQQNQINDNEELRKEIKSSEEKMKEIQSENEILKKQIEKEDENSSNISDDLQKLVNKSLV 672

Query: 1578 KELLD 1582
            KE +D
Sbjct: 673  KESID 677



 Score = 42.3 bits (95), Expect = 0.11
 Identities = 42/173 (24%), Positives = 81/173 (46%), Gaps = 10/173 (5%)

Query: 1421 HEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKES 1480
            HE + +L  + DE  N    LV  +K  +    + + ++  L+ +     + YE      
Sbjct: 146  HELSRSLQNQLDEKINQCDALVNEKKSSDKNIDQLKKQIEQLKSQFKLETSRYEKQIDVY 205

Query: 1481 EIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEI 1540
            E+E  KL +E N K  +S + N + +E+NK L++++ K   +Q  L+ + ++ V   D +
Sbjct: 206  ELELAKLADEHNNKNDQSNTSNSE-SEINK-LKQQLIK---LQNDLDEERVKSVATEDRL 260

Query: 1541 TNL-QNMVRASSSKIQKHVSFASDTKQGRDEQ--LDNTMNKELLDAVPRAELD 1590
            T   +   +A S+   ++ +        + EQ    N  N ELL    ++E+D
Sbjct: 261  TKFREESSKAISTLKSQNSNLQEQLSLSKIEQNSAQNAGNDELLKI--KSEID 311


>UniRef50_Q237L2 Cluster: Kinesin motor domain containing protein;
            n=2; Tetrahymena thermophila|Rep: Kinesin motor domain
            containing protein - Tetrahymena thermophila SB210
          Length = 2307

 Score =  177 bits (430), Expect = 3e-42
 Identities = 286/1451 (19%), Positives = 635/1451 (43%), Gaps = 145/1451 (9%)

Query: 147  LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINE---KDQIIEAKNKATTXXXXXXXXX 203
            L   +  KD+ +  +++  + M   I++LQE +N+     Q +E   +            
Sbjct: 433  LQQELDGKDDQIHKMEIFQQQMVKKIMELQEDLNKVKLDKQELEGSQRHLKQSLCQGVKQ 492

Query: 204  XXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAA 263
                    +  K ++  +++ +  +  + ++E +  L++ +   +     EE ++L E  
Sbjct: 493  QDTIVLLEQQKKVEVENIEKKYQELLKQTENELKSFLEEFDKTSLEYE--EEIDQLKE-- 548

Query: 264  RFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTE 323
                  ++ K  Q++E                 ++ +      K    EK + E     E
Sbjct: 549  ------QNIKYLQDIENYAKQTESLNDQLKQKNEEIVNLENTYKNLESEKENSE-QQFIE 601

Query: 324  LTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMK 383
            L+++ +L+++   + R+ N + + K+       K   + S K        +     + +K
Sbjct: 602  LSQQFKLIDN-GYKEREENYKKQIKMNEQKASLKEKENVSLKEQLKQQENAQSQALNTLK 660

Query: 384  SPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNK-DLVDKEYVISEKDTXXXXXXXXX 442
                +LS +  N+   +++NK  I+  E   Q L + D+V  EY  S+ D          
Sbjct: 661  EEIQELSKQ--NKVLQEELNKKTISISEREKQHLQELDIVKSEYT-SQFDYLNSERESLK 717

Query: 443  XGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLI 502
               +     L+ E +Q  E      +    +++ E  K+  +  +E +  ++ + +K + 
Sbjct: 718  SSLEKGRVDLEQELKQARE-----QIEKQKQEIVEYEKIVNESNEEKSMMMQQLEIK-ID 771

Query: 503  EKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTE 562
            E ++  + +I  +  ++   ++ +   K++++  L +  +  +++    +   E ++  +
Sbjct: 772  ELIQHNKREIASMKKQLTEKDQYIQNQKNSYEQLLNKYNELQEDYEDCQEQQSEEIQKNK 831

Query: 563  ELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEM--ENLAETRLKAISLLE 620
             L  + +K  +L++ +  L+  L DYD     +S  Y+  IE   +N+ +   K   L+E
Sbjct: 832  NL--IKEKEEKLQQVQQQLEEQLQDYDQ----KSSSYQSQIEQLNQNIEQLNQKIEQLIE 885

Query: 621  SQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELAL 680
             QK  +  +  I  ++Y     +  D+  L        IK+   + Q +A+    K+   
Sbjct: 886  -QKQQMESQFEIDIEQYKNKNQQ--DLENL-------NIKTAQSQLQSEAI---LKQFNQ 932

Query: 681  VIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISEL-LAKI 739
             IE L L   Q           K+ ++ K +  I++  +  DKL    +E+ S+L L +I
Sbjct: 933  QIEQLNLTNSQ-----------KDQLIAKQKEQIEQQTEQLDKLNTELSEQSSQLSLIQI 981

Query: 740  NHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKA 799
            N++E   IQ     + ++  +   + + + +++  K  I  L + I    DR+  +E   
Sbjct: 982  NNQELI-IQLD-ETEKQLNTQKQQLNHSQQQITDLKKEISILNQEIF---DRKKEIESYV 1036

Query: 800  DQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILL 859
                 + Q+ ++   E  ++E +  N +    D   ++++ L++ + + +EL++  + ++
Sbjct: 1037 KSNNQFEQKIEQLKQEIVVKEFQHENEIQEKKD---MLQEHLIQFKDKEEELKQAREDII 1093

Query: 860  EENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIV 919
             E  + ++ L  +Q   + L +K     + + ++ K + QL  +    +++  + Q+ + 
Sbjct: 1094 NEKNSFEVVLKSIQNQNSELEQK-----IVDLKNDKERLQL--IVEEKEKVILDLQSQLQ 1146

Query: 920  QKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVE 979
            +K  +I+ +  E +++IE+A+  K       +++I+ +     Q+++  NN+++  +++E
Sbjct: 1147 EKCSQIQQIS-EISSEIETALEQK-------QQHIQLLLLKNTQVEDQINNLKDQILDLE 1198

Query: 980  ELNKMNLEL---IDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQ 1036
            E+NK N+E    +   +Q++  Q  +  EQ   ++ +LNA + Q ++E   L  KINN Q
Sbjct: 1199 EINKQNVEKQENLQTQLQQKSIQQQEQNEQNAEQVCQLNAQIAQLNQE---LEDKINNLQ 1255

Query: 1037 VSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHN-EELQILVREQDDQIKEL 1095
                        KL Q  T L+ + E      K++LD+K +  E L++  ++ +  + EL
Sbjct: 1256 ------------KLNQ--TYLDQIRE-----IKEILDAKNNEIESLKLSQQQIELSMGEL 1296

Query: 1096 KETKLTFEMNIPK--TEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQE 1153
            K      E N+ +  TE   +   I+ +++ AN  +            L    +E   Q 
Sbjct: 1297 KSIFEESESNLQQKNTENENLKDKIKELTEKANEYENEMKEQNDEINQLTESNKEIQGQL 1356

Query: 1154 RSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNL 1213
            +S ++  + +L +  QE      QL+     ++  + +NQ Q  +++ K+ Q+  E +N 
Sbjct: 1357 QSEIENLNQQLESHQQEIAELKGQLDIQIQLVSEGENLNQNQQLEIEQKIAQM-IEQENQ 1415

Query: 1214 LSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLD 1273
            +    +L++ I+   ++R   I  L KQ  A+++A  +K E E++      E   +  ++
Sbjct: 1416 VKQF-QLKAQIN---EER---IMILEKQVQAKQQAIEEKME-EIKKHKENVEQVLQTEIN 1467

Query: 1274 SVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQE-KYADVINQIEILRSEIEDEKV 1332
              QS   E   K +  E   SLQ +L+D+ E + N  E K      +IE L+++ ED   
Sbjct: 1468 DKQSIINEYQEKFIEQE---SLQKQLEDQIEQIVNQYEVKLETKQTEIEELQNQYEDLHN 1524

Query: 1333 AFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEE---NAQLKKSSXXXXXXXX 1389
             F                 L ++N+  K+  E    N+NE+     Q K+          
Sbjct: 1525 QFEAFQQESNEQFQFNIKKLESQNEELKEQIE----NLNEKMCLEIQDKEQQKQNNENLL 1580

Query: 1390 XXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDE-FENVRQQLVEYEKRI 1448
                 + D  +K +E    + + + +  ++ +     L  +N +  E ++Q  +E  K+I
Sbjct: 1581 SQIQSIKDENSKKIEELELIIISEKQQVEQLNLKISDLNLQNQKLLEQLKQVELENAKKI 1640

Query: 1449 EDLTYEKESELAILRLKMHENA-----NHYETMQKESEIERVKLIEELNVKITE-SVSLN 1502
             +L  + E ++ ++ ++  + +     N +  +QK+  I+R   + +L +K  + +   N
Sbjct: 1641 NNLQIDLEDKINLIHVQTQQLSCMIIQNAFRRIQKQKIIKR--YLNQLALKTRKLNAEQN 1698

Query: 1503 K-QVAEL-NKALEEEVAKTNEMQTALENQEIEIVTLNDEIT---NLQNMVRASSSKIQKH 1557
            K + AE+ NK   +++    E+ T L+ Q  ++   NDEI      Q+ +   + K  K 
Sbjct: 1699 KLEQAEIENKKQYDQLLYQAELDTYLQEQIKKLNEQNDEINQRIQQQDQILQENEKQLKK 1758

Query: 1558 VSFA--SDTKQ 1566
            +     SDT+Q
Sbjct: 1759 LQIEKDSDTQQ 1769



 Score =  158 bits (383), Expect = 1e-36
 Identities = 259/1187 (21%), Positives = 518/1187 (43%), Gaps = 141/1187 (11%)

Query: 484  QLKQELN---DEIKDVNV--KDLIEKLKSAEEQITQLN---DEIDAANKNMIK-----VK 530
            QL+QEL+   D+I  + +  + +++K+   +E + ++     E++ + +++ +     VK
Sbjct: 432  QLQQELDGKDDQIHKMEIFQQQMVKKIMELQEDLNKVKLDKQELEGSQRHLKQSLCQGVK 491

Query: 531  SNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEE-----LHHLSQKVAELEEEKGNLQLHL 585
                + L + QK ++    +    +E+++ TE      L    +   E EEE   L+   
Sbjct: 492  QQDTIVLLEQQKKVE-VENIEKKYQELLKQTENELKSFLEEFDKTSLEYEEEIDQLKEQN 550

Query: 586  VDYDSGRMIESDVYKKMIE-MENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKL 644
            + Y    + + + Y K  E + +  + + + I  LE+   +L  E    +Q++ E+  + 
Sbjct: 551  IKY----LQDIENYAKQTESLNDQLKQKNEEIVNLENTYKNLESEKENSEQQFIELSQQF 606

Query: 645  ADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKE 704
              I     ++  +  K + + EQ     AS KE     EN+ L KEQL    K  EN + 
Sbjct: 607  KLIDNGYKEREENYKKQIKMNEQ----KASLKEK----ENVSL-KEQL----KQQENAQS 653

Query: 705  DIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYI 764
              +N L+  IQE      K  K+  E++++    I+  E+  +Q    +D    E     
Sbjct: 654  QALNTLKEEIQE----LSKQNKVLQEELNKKTISISEREKQHLQE---LDIVKSEYTSQF 706

Query: 765  ENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELV 824
            + + SE    KS    LE+    +E        + ++    + E +K  +E   ++  ++
Sbjct: 707  DYLNSERESLKSS---LEKGRVDLEQELKQAREQIEKQKQEIVEYEKIVNESNEEKSMMM 763

Query: 825  NRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKAN 884
             +L + +D   +++    EI    K+L +K+Q +    QN + S   +   YN L E   
Sbjct: 764  QQLEIKIDE--LIQHNKREIASMKKQLTEKDQYI----QNQKNSYEQLLNKYNELQEDYE 817

Query: 885  RTDLAESEST-KYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDK 943
                 +SE   K +  +++ E  L+++    Q  + ++ ++ +     + +QIE   ++ 
Sbjct: 818  DCQEQQSEEIQKNKNLIKEKEEKLQQV----QQQLEEQLQDYDQKSSSYQSQIEQLNQNI 873

Query: 944  KVLNEKYEKNIEYVTQLEAQLQEYKNNIENL-NMNVEELNKMNLELIDKHVQKQQTQSPD 1002
            + LN+K E+ IE   Q+E+Q   ++ +IE   N N ++L  +N++       + Q QS  
Sbjct: 874  EQLNQKIEQLIEQKQQMESQ---FEIDIEQYKNKNQQDLENLNIK-----TAQSQLQSEA 925

Query: 1003 YTEQYINEINKLNALLKQKDEEIIALNQKI--NNAQVSYMSM-VSDYESKLA-------Q 1052
              +Q+  +I +LN    QKD+ I    ++I     Q+  ++  +S+  S+L+       +
Sbjct: 926  ILKQFNQQIEQLNLTNSQKDQLIAKQKEQIEQQTEQLDKLNTELSEQSSQLSLIQINNQE 985

Query: 1053 FTTKLENMEEEMQRVSKQLLDSKQH----NEELQILVREQDDQIKELK---ETKLTFEMN 1105
               +L+  E+++    +QL  S+Q      +E+ IL +E  D+ KE++   ++   FE  
Sbjct: 986  LIIQLDETEKQLNTQKQQLNHSQQQITDLKKEISILNQEIFDRKKEIESYVKSNNQFEQK 1045

Query: 1106 IPKTEGMIISSTIE---PMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSA 1162
            I + +  I+    +    + +  + +             LK Q  E+ I E++  +    
Sbjct: 1046 IEQLKQEIVVKEFQHENEIQEKKDMLQEHLIQFKDKEEELK-QAREDIINEKNSFEVVLK 1104

Query: 1163 KLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRS 1222
             +  +  E   KI+ L+     L       ++ I  L+S+L+    E  + +  ++E+ S
Sbjct: 1105 SIQNQNSELEQKIVDLKNDKERLQLIVEEKEKVILDLQSQLQ----EKCSQIQQISEISS 1160

Query: 1223 SISSAVDQRGFEI-AELWKQHLAQREADFQKTE----HELRVQ-LSAFESKYEQLLD-SV 1275
             I +A++Q+   I   L K    + + +  K +     E+  Q +   E+   QL   S+
Sbjct: 1161 EIETALEQKQQHIQLLLLKNTQVEDQINNLKDQILDLEEINKQNVEKQENLQTQLQQKSI 1220

Query: 1276 QSSTQEETNKIVTME---QVTSLQNKLQDKEEHLRNLQEKYADVINQI-EIL---RSEIE 1328
            Q   Q E N     +   Q+  L  +L+DK  +L+ L + Y D I +I EIL    +EIE
Sbjct: 1221 QQQEQNEQNAEQVCQLNAQIAQLNQELEDKINNLQKLNQTYLDQIREIKEILDAKNNEIE 1280

Query: 1329 DEKVA---FXXXXXXXXXXXXXXXXDLR---TENQSYKQMQEQSILNINEENAQLKKSSX 1382
              K++                    +L+   TEN++ K   ++     NE   ++K+ + 
Sbjct: 1281 SLKLSQQQIELSMGELKSIFEESESNLQQKNTENENLKDKIKELTEKANEYENEMKEQND 1340

Query: 1383 XXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQ-QL 1441
                            ++++  L  QLE    EI +   +  I + Q   E EN+ Q Q 
Sbjct: 1341 EINQLTESNKEIQGQLQSEIENLNQQLESHQQEIAELKGQLDIQI-QLVSEGENLNQNQQ 1399

Query: 1442 VEYEKRIEDLTYEKESELAILRLKMHENANHYETMQK---------ESEIERVKLIEE-- 1490
            +E E++I  +  E+E+++   +LK   N      ++K         E ++E +K  +E  
Sbjct: 1400 LEIEQKIAQM-IEQENQVKQFQLKAQINEERIMILEKQVQAKQQAIEEKMEEIKKHKENV 1458

Query: 1491 ---LNVKITESVSLNKQVAE-------LNKALEEEVAK-TNEMQTALENQEIEIVTLNDE 1539
               L  +I +  S+  +  E       L K LE+++ +  N+ +  LE ++ EI  L ++
Sbjct: 1459 EQVLQTEINDKQSIINEYQEKFIEQESLQKQLEDQIEQIVNQYEVKLETKQTEIEELQNQ 1518

Query: 1540 ITNLQNMVRA----SSSKIQKHVSFASDTKQGRDEQLDNTMNKELLD 1582
              +L N   A    S+ + Q ++       +   EQ++N   K  L+
Sbjct: 1519 YEDLHNQFEAFQQESNEQFQFNIKKLESQNEELKEQIENLNEKMCLE 1565



 Score =  149 bits (360), Expect = 8e-34
 Identities = 257/1414 (18%), Positives = 603/1414 (42%), Gaps = 89/1414 (6%)

Query: 212  EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271
            +  +QQ+ +  +++    + ++ + ++L ++IE  + +I  L E  + +E+ +FEI +E 
Sbjct: 842  QQVQQQLEEQLQDYDQKSSSYQSQIEQLNQNIEQLNQKIEQLIEQKQQMES-QFEIDIEQ 900

Query: 272  --SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIE 329
              +K  Q+LE               + KQ  +   +      +K  L      ++ ++ E
Sbjct: 901  YKNKNQQDLENLNIKTAQSQLQSEAILKQFNQQIEQLNLTNSQKDQLIAKQKEQIEQQTE 960

Query: 330  LLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASK----MKSP 385
             L+ LN ++ + + +L   L  +  +   +     +   L ++K   N + +    +K  
Sbjct: 961  QLDKLNTELSEQSSQLS--LIQINNQELIIQLDETE-KQLNTQKQQLNHSQQQITDLKKE 1017

Query: 386  WSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYV----ISEKDTXXXXXXXX 441
             S L+ E  ++  + +       + E  I+ L +++V KE+     I EK          
Sbjct: 1018 ISILNQEIFDRKKEIESYVKSNNQFEQKIEQLKQEIVVKEFQHENEIQEKKDMLQEHLIQ 1077

Query: 442  XXGKDTLIAQLQ---LEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQ-ELNDEIKDVN 497
               K+  + Q +   +  +   E         N+E   +I  ++   ++ +L  E K+  
Sbjct: 1078 FKDKEEELKQAREDIINEKNSFEVVLKSIQNQNSELEQKIVDLKNDKERLQLIVEEKEKV 1137

Query: 498  VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNH-KLKLKQMQKTIDNFSKVSDSNKE 556
            + DL  +L+    QI Q++ EI +  +  ++ K  H +L L +  +  D  + + D   +
Sbjct: 1138 ILDLQSQLQEKCSQIQQIS-EISSEIETALEQKQQHIQLLLLKNTQVEDQINNLKDQILD 1196

Query: 557  IVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAI 616
            +  + ++     + +    ++K   Q    + ++ ++ + +     +  E   E ++  +
Sbjct: 1197 LEEINKQNVEKQENLQTQLQQKSIQQQEQNEQNAEQVCQLNAQIAQLNQE--LEDKINNL 1254

Query: 617  SLLESQKFDLVQEL-HILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASK 675
              L     D ++E+  IL  K +E+E     +SQ Q +    E+KS+  EE    L    
Sbjct: 1255 QKLNQTYLDQIREIKEILDAKNNEIES--LKLSQQQIELSMGELKSI-FEESESNLQQKN 1311

Query: 676  KELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISEL 735
             E     ENLK   ++L     + EN+ ++  +++    + N ++  +L+    E +++ 
Sbjct: 1312 TEN----ENLKDKIKELTEKANEYENEMKEQNDEINQLTESNKEIQGQLQS-EIENLNQQ 1366

Query: 736  LAKINHEEQSKIQTQFGIDAKI--------QERDLYIENIESELSKYKSRICRLEESIAV 787
            L   + +E ++++ Q  I  ++        Q + L IE   +++ + ++++ + +    +
Sbjct: 1367 LES-HQQEIAELKGQLDIQIQLVSEGENLNQNQQLEIEQKIAQMIEQENQVKQFQLKAQI 1425

Query: 788  MEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVV-EKQLLEIEH 846
             E+R   LE++       ++EK +   ++    ++++     + D   ++ E Q   IE 
Sbjct: 1426 NEERIMILEKQVQAKQQAIEEKMEEIKKHKENVEQVLQ--TEINDKQSIINEYQEKFIEQ 1483

Query: 847  ENKELQKKNQILLEENQ---NLQISLSDMQQHYNALVEKANRTDLAESESTK-YQTQLRD 902
            E+ + Q ++QI    NQ    L+   +++++  N   +  N+ +  + ES + +Q  ++ 
Sbjct: 1484 ESLQKQLEDQIEQIVNQYEVKLETKQTEIEELQNQYEDLHNQFEAFQQESNEQFQFNIKK 1543

Query: 903  LESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEA 962
            LES  + +  + + L  +   EI+D E +     E+ +   + + ++  K IE   +LE 
Sbjct: 1544 LESQNEELKEQIENLNEKMCLEIQDKEQQKQNN-ENLLSQIQSIKDENSKKIE---ELEL 1599

Query: 963  QLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKD 1022
             +   K  +E LN+ + +LN  N +L+++  Q +   +       I+  +K+N +  Q  
Sbjct: 1600 IIISEKQQVEQLNLKISDLNLQNQKLLEQLKQVELENAKKINNLQIDLEDKINLIHVQTQ 1659

Query: 1023 EE--IIALN--QKINNAQV--SYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQ 1076
            +   +I  N  ++I   ++   Y++ ++    KL     KLE  E E ++   QLL   +
Sbjct: 1660 QLSCMIIQNAFRRIQKQKIIKRYLNQLALKTRKLNAEQNKLEQAEIENKKQYDQLLYQAE 1719

Query: 1077 HNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXX 1136
             +  LQ  +++ ++Q  E+ +     +  + + E  +    IE  S D   ++       
Sbjct: 1720 LDTYLQEQIKKLNEQNDEINQRIQQQDQILQENEKQLKKLQIEKDS-DTQQMNFYIEKIS 1778

Query: 1137 XXXXXLKVQEEE--EFIQERSVLQEQSAKLNTELQECYTKIIQLETL--NTELTGHDVVN 1192
                 +K +EE+  +   E S L +Q       ++E   ++  ++++  N +     +  
Sbjct: 1779 NLNQDIKAKEEQLAQSYDELSNLSKQLRICTNSVEELQFQLKNIKSVHDNIDFKVRKIQI 1838

Query: 1193 QEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQK 1252
              Q + L+ +L    + N+ L   V +L    ++ +  +  E +   KQ L Q + D Q 
Sbjct: 1839 TFQKHLLRKELNAAISNNEQLQQNVDDLIQK-NTLLQYQNEEFSITNKQALDQIQ-DEQN 1896

Query: 1253 TEHELRVQLSAFES---KYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNL 1309
               EL+++L    +   K +Q+++  +++  E  NKI+ +EQ+      + +++    N 
Sbjct: 1897 KIVELQLELKEKNTCIEKVQQMIEKRETNLTELENKIINLEQLQKENQVIINQQFKQLNE 1956

Query: 1310 QEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTE--NQSYKQMQEQSI 1367
            Q      +N I ++   I  +K                   + + E  ++     Q   +
Sbjct: 1957 QNYKFKCMNSIRVISKFIAQKKWQQTVKKLMGAFAIQKIHFEKQIEVLDEKVAGYQIMKL 2016

Query: 1368 LNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITL 1427
            L       QL + +             +   +++V E    +  K S++Y++  E +   
Sbjct: 2017 LKQRVSEQQLNQYNRLIIERQKT----IEFLQSQV-EKEQYIFRKASQVYER--EVSARK 2069

Query: 1428 TQRNDEFENVRQQLVEYEKRIEDL---TYEKESELAILRLKMHENANHYETMQKESEIER 1484
             Q       V Q L  Y+++I++L    Y+ + ++  L+ ++++       ++ E E E+
Sbjct: 2070 IQSAYRLFKVNQILYRYKQQIDNLRKINYDYKEKIDRLQEQLYD-------LEDEIEKEK 2122

Query: 1485 VKLIEELNVKI-TESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNL 1543
              + ++ N ++  E   L + +  LN   ++   +    +  + + +    TL  ++  L
Sbjct: 2123 SVISQQQNEQVFQERGFLQENINLLNTEFKKNEPQRGSRENQISSLQKSEKTLKQKLKEL 2182

Query: 1544 QNMVRASSSKIQ-KHVSFASDTKQGRDEQLDNTM 1576
                +   + ++ KH+    D KQ   E  + T+
Sbjct: 2183 DQSWKNQYTHLENKHLELQKD-KQILTESYEQTL 2215



 Score = 96.3 bits (229), Expect = 6e-18
 Identities = 190/938 (20%), Positives = 403/938 (42%), Gaps = 90/938 (9%)

Query: 153  EKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXE 212
            E++N +   Q+K +I E  I+ L++++  K Q IE K +                     
Sbjct: 1411 EQENQVKQFQLKAQINEERIMILEKQVQAKQQAIEEKMEEIKKHKENVEQVLQTEI---N 1467

Query: 213  DTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHS 272
            D +  + + QE FI  E+  K  + ++ + +   +V++ + +   + L+    ++  +  
Sbjct: 1468 DKQSIINEYQEKFIEQESLQKQLEDQIEQIVNQYEVKLETKQTEIEELQNQYEDLHNQFE 1527

Query: 273  KLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIE-LL 331
               QE  +                K+ IE        + EK  LEI +  +  +  E LL
Sbjct: 1528 AFQQESNEQFQFNIKKLESQNEELKEQIE-------NLNEKMCLEIQDKEQQKQNNENLL 1580

Query: 332  EHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSS 391
              +     + +K++E     + +E + V   + K S L  +        K     +    
Sbjct: 1581 SQIQSIKDENSKKIEELELIIISEKQQVEQLNLKISDLNLQNQKLLEQLKQVELENAKKI 1640

Query: 392  ETLNQDTDKKINKNEIAKLE---MVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTL 448
              L  D + KIN   +   +   M+IQ+  +  + K+ +I                +   
Sbjct: 1641 NNLQIDLEDKINLIHVQTQQLSCMIIQNAFRR-IQKQKIIKRYLNQLALKTRKLNAEQNK 1699

Query: 449  IAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSA 508
            + Q ++E+++  +   L     +T    +I K+ EQ     NDEI    ++   + L+  
Sbjct: 1700 LEQAEIENKKQYD-QLLYQAELDTYLQEQIKKLNEQ-----NDEINQ-RIQQQDQILQEN 1752

Query: 509  EEQITQLNDEIDAANKNM---IKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELH 565
            E+Q+ +L  E D+  + M   I+  SN    +K  ++      +++ S  E+  L+++L 
Sbjct: 1753 EKQLKKLQIEKDSDTQQMNFYIEKISNLNQDIKAKEE------QLAQSYDELSNLSKQLR 1806

Query: 566  HLSQKVAELEEEKGNLQ-LH-LVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQK 623
              +  V EL+ +  N++ +H  +D+   R I+    K ++  E      +     L+   
Sbjct: 1807 ICTNSVEELQFQLKNIKSVHDNIDFKV-RKIQITFQKHLLRKE--LNAAISNNEQLQQNV 1863

Query: 624  FDLVQELHILQQKYDE--VEDKLADISQLQSDQVCSEIKSVHLE--------EQIDALSA 673
             DL+Q+  +LQ + +E  + +K A + Q+Q +Q  ++I  + LE        E++  +  
Sbjct: 1864 DDLIQKNTLLQYQNEEFSITNKQA-LDQIQDEQ--NKIVELQLELKEKNTCIEKVQQMIE 1920

Query: 674  SKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEK-- 731
             ++     +EN  ++ EQL    + + N +   +N+ QNY  + M+    + K  A+K  
Sbjct: 1921 KRETNLTELENKIINLEQLQKENQVIINQQFKQLNE-QNYKFKCMNSIRVISKFIAQKKW 1979

Query: 732  ---ISELLA-----KINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEE 783
               + +L+      KI+ E+Q ++  +     +I +  L     E +L++Y   I   ++
Sbjct: 1980 QQTVKKLMGAFAIQKIHFEKQIEVLDEKVAGYQIMKL-LKQRVSEQQLNQYNRLIIERQK 2038

Query: 784  SIAVME---DRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQ 840
            +I  ++   ++   + RKA Q+       +K  S Y + +   VN+  +L  + + ++  
Sbjct: 2039 TIEFLQSQVEKEQYIFRKASQVYEREVSARKIQSAYRLFK---VNQ--ILYRYKQQIDN- 2092

Query: 841  LLEIEHENKE-LQKKNQIL--LEENQNLQISLSDMQQHYNALVEKA---NRTDLAESEST 894
            L +I ++ KE + +  + L  LE+    + S+   QQ+     E+       +L  +E  
Sbjct: 2093 LRKINYDYKEKIDRLQEQLYDLEDEIEKEKSVISQQQNEQVFQERGFLQENINLLNTEFK 2152

Query: 895  KYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAI----RDKKVLNEKY 950
            K + Q    E+ +  +    +TL  QK KE++       T +E+      +DK++L E Y
Sbjct: 2153 KNEPQRGSRENQISSLQKSEKTL-KQKLKELDQSWKNQYTHLENKHLELQKDKQILTESY 2211

Query: 951  EKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINE 1010
            E+ +  + + +A L EY+N IE +N   ++  +    +I  +V+ ++ Q     E+   E
Sbjct: 2212 EQTLAIIKKDKALLIEYQNQIE-INRRQDKAAR----IIQNYVKNRKLQQEQ--EKLQKE 2264

Query: 1011 INKLNALLKQKDEEI--IALNQKINNAQVSYMSMVSDY 1046
               L+ + K K+ +       Q + N    + +++ ++
Sbjct: 2265 KEDLSKIFKLKNAQTGQYLFQQSLKNVNQIFTNLIQNF 2302


>UniRef50_A2EVM3 Cluster: Viral A-type inclusion protein, putative;
            n=2; Trichomonas vaginalis G3|Rep: Viral A-type inclusion
            protein, putative - Trichomonas vaginalis G3
          Length = 2207

 Score =  175 bits (427), Expect = 6e-42
 Identities = 294/1508 (19%), Positives = 646/1508 (42%), Gaps = 125/1508 (8%)

Query: 92   ESLANTLKQKEILMEKIKQY-KELSKR-SSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSN 149
            E+L NT  + E   +K+K+  K ++ R    +                  +L  +T + +
Sbjct: 467  ENLQNTPDKSEEFNQKLKELEKAINDRLKQNSETDAKNKQLQDAVDNKNRELETITVVQD 526

Query: 150  TIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXX 209
              +E    L+ ++ +++ ++    +L +K+NE    I+                      
Sbjct: 527  NSEELQKQLNDIKDQIEKLKNNSNELTDKLNELKSNIDTDKGVLDSLNDNADVLNVQIEE 586

Query: 210  XXEDTKQQMTKMQENF--IAMEAEWKDEKQRLLKDIESK-DVRISSLEEA-NKLLEAARF 265
              ++ ++   K+QE    IA + E   EK   +++ +++ D  I ++EE  N+  +    
Sbjct: 587  KNQEYERLEDKIQELIADIATKTEKVGEKDAQVEEKKAQLDELIKAIEERKNQSEQNNEN 646

Query: 266  EISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELT 325
              SL+H     E ++               ++Q+ E +   + +I+EK     A + EL 
Sbjct: 647  NDSLQHQ--IDEKQRQLDELIKAIEERKNQSEQNKENNDSLQQQIDEKK----AQLDELN 700

Query: 326  KKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSP 385
            K IE  ++ + Q  + N  L+ +          +    ++   LI     R    K +S 
Sbjct: 701  KAIEERKNQSEQNNENNDSLQQQ----------IDEKQRQLDELIKAIEER----KNQSE 746

Query: 386  WSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISE--KDTXXXXXXXXXX 443
             ++ ++++L Q  D+K  + E  K    I   +++L ++  ++ +   D           
Sbjct: 747  QNKENNDSLQQQIDEKQRQLEAIKN---IPDNSEELKNQLQILEKAFNDKMEQNAANNKQ 803

Query: 444  GKDTLIAQL-QLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLI 502
             +D + ++  +LE+   ++  S   +    +D+NE  + ++   +EL D++++++    I
Sbjct: 804  LQDAIDSKKKELENTPEVQDNSE-ELKKQLDDINEQIEKRKNDNKELEDKLEELS--KAI 860

Query: 503  EKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQ-KTIDNFSKVSDSNKEIVRLT 561
             + K A+E+  + N+E++      IK K   K  L  ++ KT +   K++D  K+I    
Sbjct: 861  NEQKLADEETAKKNEELE----KQIKDKEAEKNSLVPVEDKTEELARKLADLEKQIAEQL 916

Query: 562  EELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLES 621
            E+ +    K  +LE++    Q  L +      ++++  +   E EN  E  L+ ++ L+S
Sbjct: 917  EKQNETDGKNKDLEQQIKEKQEKLDE------LKNNFIEDTKEKENEIEELLQELNDLDS 970

Query: 622  QKFDLVQELHILQQKYDEVEDKL-ADIS---QLQSDQVCSEIKS-----VHLEEQID--A 670
            +  ++  ++   Q++Y+E +D + +DI+   QL  D +   +K      V  EE ID  A
Sbjct: 971  KINEIQDQISQFQEEYEEKKDHIVSDINTKDQLLQDLMEENLKQLKETPVVAEEPIDSEA 1030

Query: 671  LSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMS-- 728
            L     ++A +IE +          ++  E+  E ++N        N +L  +LE M   
Sbjct: 1031 LDKINDQMADLIERINSGDIDPSDLVEK-ESQMEALINNAIVDNHGNKELVKQLEDMRNK 1089

Query: 729  -AEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAV 787
              E+I + L +   E+  + +        ++E+   IE++E +LS+ +  +    ESI  
Sbjct: 1090 MGERIDDYLNEAEKEDLEEEEETIPEQNSVEEKQDTIEDLEQQLSQKQKDL----ESIEP 1145

Query: 788  MEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLA----------VLMDHDRVV 837
            +E ++  ++ K +++   + +KQ    E   + D L  +LA           + D    +
Sbjct: 1146 VESKKEEIQNKLNEIEKEINDKQAKNEEIKNENDALEQQLAEKKKELDSIPTVEDKTSDL 1205

Query: 838  EKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQ 897
            E QL +IE +  E + KN+   + N+  +  L++ QQ  +++ EKA      ESES + +
Sbjct: 1206 ESQLKDIESQINEKRAKNEETEKMNKEFEDKLAEKQQELDSIEEKAEEQTTPESESKEQE 1265

Query: 898  TQ----LRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKN 953
             +    L +LES ++ +       I    K+ E L +  +  I S + DK   ++  +  
Sbjct: 1266 KEESKDLSELESKIRDLLER----IAAGDKDPETL-VSVSEDILSTLNDKIATSDSDDDK 1320

Query: 954  IEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINK 1013
            + Y    +   +   N +E    ++E+      E   + V+ +    PD       E ++
Sbjct: 1321 LRY----QQASETINNAVEQYLASLEDAYNDEEEEPIQEVETRDIILPDEAANEGEEESQ 1376

Query: 1014 LNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLD 1073
             +  L+ K +E+ +    ++       S   D  +K+ +   +L   +     +S Q  +
Sbjct: 1377 QSEELETKTDELKSQIADVDREIAEQKSKNDDLMNKINELQQQLAEKQNVRDSLSAQTAE 1436

Query: 1074 SKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMI--ISSTIEPMSDDANNVDXX 1131
             ++   ++   + E+   I +L+  +   + +IP++E     +S+ I+ +  + +     
Sbjct: 1437 LEEQLSKIGHDLEEEKKAISDLQSKEAELK-SIPQSEDKSEELSARIDEIKSEIDQKKSE 1495

Query: 1132 XXXXXXXXXXLKVQEEE--EFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHD 1189
                      L+ Q E+  + +      +++S+ L  E+++  +KI   ++ N E++  +
Sbjct: 1496 NEAIESKNNELQKQLEDFKKLLDSIPTQEDKSSDLEKEIKDTQSKINDKKSKNEEISNKN 1555

Query: 1190 VVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVD--QRGFEIAELWKQHLAQRE 1247
               +EQ+ QL+ +LE L T  D L     E++++ S   D  ++  E     K+   Q E
Sbjct: 1556 NELEEQLTQLRQELETLPTVEDKLSDLENEIKNTESQINDKNEKNEETDNKNKELEQQLE 1615

Query: 1248 ADFQKTEHELRVQ--LSAFESKYEQLLDSV--QSSTQEETNKIVTMEQVTSLQNKLQDKE 1303
            +  Q+ E    V+   S  E++ + + DS+  ++S  EET+K    E  + +++K Q+ E
Sbjct: 1616 SKKQELESIPTVEDKSSELENELKSVADSINDKNSKNEETDK-KNKELESQIESKKQELE 1674

Query: 1304 EHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQ 1363
              +  +++    + N+++ +   I ++K                   + + EN   K+ +
Sbjct: 1675 S-IPVVEDNSDSLSNELKSVEESINNKK------SKNDETDKKNKELEHQIEN---KKQE 1724

Query: 1364 EQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEY 1423
             +SI  + +++ +L+               +  + + K  EL  QLE K  E+     E 
Sbjct: 1725 LESIPVVEDKSPELENELQSIESFINDKNEKNEETDNKNKELEQQLESKKQEL-----ES 1779

Query: 1424 TITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIE 1483
              T+  ++ E EN   ++   E+ I+D    K  ++     ++ E     +  QK  E+E
Sbjct: 1780 IPTVEDKSSELEN---EIQSAEESIKD-KISKNEDIDNKNKELEE-----KVAQKREELE 1830

Query: 1484 RVKLIEELNVKITESVSLNKQVAELNKALEEEV-AKTNEMQTALENQEIEIVTLNDEITN 1542
             +   E  + ++ E     ++ A    +    + ++ N++   L   ++ +   N     
Sbjct: 1831 SIPTAESKSAEVAEPSQEEQEQASTTVSSPSSIKSELNDIADLLSKGDLSLEEFNSRAEK 1890

Query: 1543 LQNMVRAS 1550
            L + + AS
Sbjct: 1891 LISQLDAS 1898



 Score =  175 bits (426), Expect = 8e-42
 Identities = 295/1421 (20%), Positives = 611/1421 (42%), Gaps = 147/1421 (10%)

Query: 175  LQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKD 234
            LQ++I+EK   ++  NKA                   +   ++  ++ E   A+E    +
Sbjct: 685  LQQQIDEKKAQLDELNKAIEERKNQSEQNNENNDSLQQQIDEKQRQLDELIKAIE----E 740

Query: 235  EKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXX 294
             K +  ++ E+ D     ++E  + LEA +  I     +L  +L+               
Sbjct: 741  RKNQSEQNKENNDSLQQQIDEKQRQLEAIK-NIPDNSEELKNQLQILEKAFNDKMEQNAA 799

Query: 295  LAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGT 354
              KQ  +    +K E+E    ++  N  EL K+++ +     + +  NKELE+KL  +  
Sbjct: 800  NNKQLQDAIDSKKKELENTPEVQ-DNSEELKKQLDDINEQIEKRKNDNKELEDKLEEL-- 856

Query: 355  ESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVI 414
             SKA++           + +   TA K        + E   Q  DK+  KN +  +E   
Sbjct: 857  -SKAINE---------QKLADEETAKK--------NEELEKQIKDKEAEKNSLVPVEDKT 898

Query: 415  QSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTED 474
            + L + L D E  I+E+            GK+  + Q   E Q+ ++      +    E 
Sbjct: 899  EELARKLADLEKQIAEQ----LEKQNETDGKNKDLEQQIKEKQEKLDELKNNFIEDTKEK 954

Query: 475  VNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEI--DAANKNMIKVKSN 532
             NEI    E+L QELND   D  + ++ +++   +E+  +  D I  D   K+ + ++  
Sbjct: 955  ENEI----EELLQELND--LDSKINEIQDQISQFQEEYEEKKDHIVSDINTKDQL-LQDL 1007

Query: 533  HKLKLKQMQKTIDNFSKVSDS------NKEIVRLTEELHHLSQKVAELEEEKGNLQLHLV 586
             +  LKQ+++T     +  DS      N ++  L E ++      ++L E++  ++  + 
Sbjct: 1008 MEENLKQLKETPVVAEEPIDSEALDKINDQMADLIERINSGDIDPSDLVEKESQMEALIN 1067

Query: 587  DYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDL------VQELHILQQKYDEV 640
            +         ++ K++ +M N    R+    L E++K DL      + E + +++K D +
Sbjct: 1068 NAIVDNHGNKELVKQLEDMRNKMGERIDDY-LNEAEKEDLEEEEETIPEQNSVEEKQDTI 1126

Query: 641  EDKLADISQLQSD-----QVCSEIKSVH-----LEEQIDALSASKKELA----LVIENLK 686
            ED    +SQ Q D      V S+ + +      +E++I+   A  +E+      + + L 
Sbjct: 1127 EDLEQQLSQKQKDLESIEPVESKKEEIQNKLNEIEKEINDKQAKNEEIKNENDALEQQLA 1186

Query: 687  LDKEQLYG--TIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAE---KISELLAKINH 741
              K++L    T++D  +D E  +  +++ I E     ++ EKM+ E   K++E   +++ 
Sbjct: 1187 EKKKELDSIPTVEDKTSDLESQLKDIESQINEKRAKNEETEKMNKEFEDKLAEKQQELDS 1246

Query: 742  -EEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKAD 800
             EE+++ QT    ++K QE++        +LS+ +S+I  L E IA  +    +L   ++
Sbjct: 1247 IEEKAEEQTTPESESKEQEKEE-----SKDLSELESKIRDLLERIAAGDKDPETLVSVSE 1301

Query: 801  QLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLE 860
             + S L +K  A S+    +D+ +         +  VE+ L  +E    + +++    ++
Sbjct: 1302 DILSTLNDKI-ATSD---SDDDKLRYQQASETINNAVEQYLASLEDAYNDEEEEP---IQ 1354

Query: 861  ENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQ 920
            E +   I L D         E AN  +    +S + +T+  +L+S +  +  E    I +
Sbjct: 1355 EVETRDIILPD---------EAANEGEEESQQSEELETKTDELKSQIADVDRE----IAE 1401

Query: 921  KKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEE 980
            +K + +DL  + N +++  + +K+ + +          +LE QL +  +++E     + +
Sbjct: 1402 QKSKNDDLMNKIN-ELQQQLAEKQNVRDSLSAQ---TAELEEQLSKIGHDLEEEKKAISD 1457

Query: 981  LNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYM 1040
            L     EL      K   QS D +E+    I+++ + + QK  E  A+  K N  Q    
Sbjct: 1458 LQSKEAEL------KSIPQSEDKSEELSARIDEIKSEIDQKKSENEAIESKNNELQ---- 1507

Query: 1041 SMVSDYESKLAQFTT---KLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELK- 1096
              + D++  L    T   K  ++E+E++    ++ D K  NEE+     E ++Q+ +L+ 
Sbjct: 1508 KQLEDFKKLLDSIPTQEDKSSDLEKEIKDTQSKINDKKSKNEEISNKNNELEEQLTQLRQ 1567

Query: 1097 --ETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQER 1154
              ET  T E  +   E  I  +T   ++D     +            L+ +++E  ++  
Sbjct: 1568 ELETLPTVEDKLSDLENEI-KNTESQINDKNEKNEETDNKNKELEQQLESKKQE--LESI 1624

Query: 1155 SVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLL 1214
              ++++S++L  EL+     I    + N E    +   + QI   K +LE +    DN  
Sbjct: 1625 PTVEDKSSELENELKSVADSINDKNSKNEETDKKNKELESQIESKKQELESIPVVEDNSD 1684

Query: 1215 STVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQL--- 1271
            S   EL+S +  +++ +  +  E  K++  + E   +  + EL   +   E K  +L   
Sbjct: 1685 SLSNELKS-VEESINNKKSKNDETDKKN-KELEHQIENKKQELE-SIPVVEDKSPELENE 1741

Query: 1272 LDSVQSSTQEETNKIV-TMEQVTSLQNKLQDKEEHLRNL---QEKYADVINQIEILRSEI 1327
            L S++S   ++  K   T  +   L+ +L+ K++ L ++   ++K +++ N+I+     I
Sbjct: 1742 LQSIESFINDKNEKNEETDNKNKELEQQLESKKQELESIPTVEDKSSELENEIQSAEESI 1801

Query: 1328 EDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXX 1387
            +D K++                   R E +S    + +S   + E + + ++ +      
Sbjct: 1802 KD-KISKNEDIDNKNKELEEKVAQKREELESIPTAESKSA-EVAEPSQEEQEQASTTVSS 1859

Query: 1388 XXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKR 1447
                   +ND    + +    LE  +S   +   +   ++   +D     + +L+E  ++
Sbjct: 1860 PSSIKSELNDIADLLSKGDLSLEEFNSRAEKLISQLDASIVNSDDP--TTKSELIEAHEQ 1917

Query: 1448 IEDLTYEKESELAILRLKMHENANHY-ETMQKESEIERVKLIEELNVKI--TESVSLNKQ 1504
            + D+  E           +H  A+   E  ++E + ++ ++IEE   K   +ES  L++ 
Sbjct: 1918 LNDIVEEY----------LHNYASAAAEEDEQEQDNDKEEIIEEQEQKQEPSESKDLSEL 1967

Query: 1505 VAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQN 1545
              ++   LE   +   + +T +   E  + TLND+I N  N
Sbjct: 1968 EQQIRDLLEHLASGDEDPETLVSVSEDILSTLNDKIANSDN 2008



 Score =  155 bits (377), Expect = 7e-36
 Identities = 238/1238 (19%), Positives = 524/1238 (42%), Gaps = 100/1238 (8%)

Query: 414  IQSLNKDLVDKEYVISEK-DTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNT 472
            I  L K+L + E  + EK D              T I   + E +    G S+       
Sbjct: 376  IDELKKELAETEKKVQEKRDALDPTYAAMVYALKTAIEAKEQELENLQNGESV------E 429

Query: 473  EDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSN 532
            E   ++A V++Q++++ N    +++++  + + ++  E +    D+ +  N+ + +++  
Sbjct: 430  ELKKKLADVEKQIEEQKNKSSDNISLEHQLAEKQAELENLQNTPDKSEEFNQKLKELEKA 489

Query: 533  HKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGR 592
               +LKQ  +T     ++ D+     R  E +  +     EL+++  +++  +    +  
Sbjct: 490  INDRLKQNSETDAKNKQLQDAVDNKNRELETITVVQDNSEELQKQLNDIKDQIEKLKNN- 548

Query: 593  MIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQS 652
               +++  K+ E+++  +T    +  L      L  ++    Q+Y+ +EDK   I +L +
Sbjct: 549  --SNELTDKLNELKSNIDTDKGVLDSLNDNADVLNVQIEEKNQEYERLEDK---IQELIA 603

Query: 653  DQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQN 712
            D      K    + Q++   A   EL   IE  K   EQ       L++  ++   +L  
Sbjct: 604  DIATKTEKVGEKDAQVEEKKAQLDELIKAIEERKNQSEQNNENNDSLQHQIDEKQRQLDE 663

Query: 713  YIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELS 772
             I+   +  ++ E+ + E    L  +I+ ++    +    I+ +  + +   EN +S   
Sbjct: 664  LIKAIEERKNQSEQ-NKENNDSLQQQIDEKKAQLDELNKAIEERKNQSEQNNENNDSLQQ 722

Query: 773  KYKSRICRLEESIAVMEDRRYSLERKA---DQLGSYLQEKQK---AYSEYTIQEDELVNR 826
            +   +  +L+E I  +E+R+   E+     D L   + EKQ+   A        +EL N+
Sbjct: 723  QIDEKQRQLDELIKAIEERKNQSEQNKENNDSLQQQIDEKQRQLEAIKNIPDNSEELKNQ 782

Query: 827  LAVL-------MDHDRVVEKQLLE-IEHENKELQKKNQILLEENQNLQISLSDMQQHYNA 878
            L +L       M+ +    KQL + I+ + KEL+   ++  + ++ L+  L D+    N 
Sbjct: 783  LQILEKAFNDKMEQNAANNKQLQDAIDSKKKELENTPEV-QDNSEELKKQLDDI----NE 837

Query: 879  LVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIES 938
             +EK  + D  E E  K + +L    +  K    E      + +K+I+D E E N+ +  
Sbjct: 838  QIEK-RKNDNKELED-KLE-ELSKAINEQKLADEETAKKNEELEKQIKDKEAEKNSLV-- 892

Query: 939  AIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDK---HVQK 995
             + DK    E   K  +   Q+  QL E +N  +  N ++E+  K   E +D+   +  +
Sbjct: 893  PVEDK--TEELARKLADLEKQIAEQL-EKQNETDGKNKDLEQQIKEKQEKLDELKNNFIE 949

Query: 996  QQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTT 1055
               +  +  E+ + E+N L++ + +  ++I    ++    +   +S ++  +  L     
Sbjct: 950  DTKEKENEIEELLQELNDLDSKINEIQDQISQFQEEYEEKKDHIVSDINTKDQLLQDLME 1009

Query: 1056 KLENMEEEMQRVSKQLLDSK---QHNEELQIL---VREQDDQIKEL--KETKLTFEMNIP 1107
            +     +E   V+++ +DS+   + N+++  L   +   D    +L  KE+++   +N  
Sbjct: 1010 ENLKQLKETPVVAEEPIDSEALDKINDQMADLIERINSGDIDPSDLVEKESQMEALINNA 1069

Query: 1108 KTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTE 1167
              +       ++ + D  N +               ++EEEE I E++ ++E+   +   
Sbjct: 1070 IVDNHGNKELVKQLEDMRNKMGERIDDYLNEAEKEDLEEEEETIPEQNSVEEKQDTIEDL 1129

Query: 1168 LQECYTKIIQLETLN-TELTGHDVVN-----QEQINQLKSKLEQLNTENDNLLSTVAELR 1221
             Q+   K   LE++   E    ++ N     +++IN  ++K E++  END L   +AE +
Sbjct: 1130 EQQLSQKQKDLESIEPVESKKEEIQNKLNEIEKEINDKQAKNEEIKNENDALEQQLAEKK 1189

Query: 1222 SSISS--AVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKY---EQLLDSVQ 1276
              + S   V+ +  ++    K   +Q      K E E       FE K    +Q LDS++
Sbjct: 1190 KELDSIPTVEDKTSDLESQLKDIESQINEKRAKNE-ETEKMNKEFEDKLAEKQQELDSIE 1248

Query: 1277 SSTQEETN-KIVTMEQVTSLQNKLQDKEEHLRNLQEKYA--------------DVINQI- 1320
               +E+T  +  + EQ       L + E  +R+L E+ A              D+++ + 
Sbjct: 1249 EKAEEQTTPESESKEQEKEESKDLSELESKIRDLLERIAAGDKDPETLVSVSEDILSTLN 1308

Query: 1321 -EILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLR-----TENQSYKQMQEQSILNINE-- 1372
             +I  S+ +D+K+ +                 L       E +  ++++ + I+  +E  
Sbjct: 1309 DKIATSDSDDDKLRYQQASETINNAVEQYLASLEDAYNDEEEEPIQEVETRDIILPDEAA 1368

Query: 1373 -ENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRN 1431
             E  +  + S            ++ D + ++ E     + K+ ++  K +E    L ++ 
Sbjct: 1369 NEGEEESQQSEELETKTDELKSQIADVDREIAE----QKSKNDDLMNKINELQQQLAEKQ 1424

Query: 1432 DEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKL-IEE 1490
            +  +++  Q  E E+++  + ++ E E   +     + A      Q E + E +   I+E
Sbjct: 1425 NVRDSLSAQTAELEEQLSKIGHDLEEEKKAISDLQSKEAELKSIPQSEDKSEELSARIDE 1484

Query: 1491 LNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRAS 1550
            +  +I +  S N+ +   N  L++++    ++  ++  QE +   L  EI + Q+ +   
Sbjct: 1485 IKSEIDQKKSENEAIESKNNELQKQLEDFKKLLDSIPTQEDKSSDLEKEIKDTQSKINDK 1544

Query: 1551 SSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAE 1588
             SK ++     S+     +EQL  T  ++ L+ +P  E
Sbjct: 1545 KSKNEE----ISNKNNELEEQL--TQLRQELETLPTVE 1576



 Score =  153 bits (370), Expect = 5e-35
 Identities = 264/1462 (18%), Positives = 618/1462 (42%), Gaps = 131/1462 (8%)

Query: 212  EDTKQQMTKMQENFIAME---AEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEIS 268
            ED K  +  ++ + ++ E   ++ ++E++    DI   + +++SL+  N  L     E+S
Sbjct: 18   EDNKSAIEDLRRDVVSEEDLHSQLENEQEASFADISELNAKLASLQTDNSFLP----EVS 73

Query: 269  LEHSKLAQELEQXXXXXXXXXXXXXXLAK--QSIEPSCEEKTE-------IEEKGSLEIA 319
             EHSKL  ++                 +K  Q++E   E K +       +E+K +    
Sbjct: 74   DEHSKLLADISAIESSIADKRSRNEETSKLNQALEAELESKKKQLSFLPTVEDKSASLEN 133

Query: 320  NMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISR-KSGRNT 378
             + ++  +I      N +  + NKELE +LA +  +  ++ S +     L S+     N 
Sbjct: 134  EIKKVDSEINTKNSQNAETEKKNKELEEQLAKIQQDLDSIPSTNDNSHFLQSQIDQIINE 193

Query: 379  ASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXX 438
             +       + + E   +D DK+ N N   + +   +  + D ++ + ++ +        
Sbjct: 194  HNSHNDEPEKANKEIQQKDADKQQN-NISTESDESSKQFSSDDLNLDGLLDDIAGGYRSD 252

Query: 439  XXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKV----------------- 481
                   + +    Q  + +H +   +  +  +  D  ++A V                 
Sbjct: 253  SSLIESNNEIEDDQQSVNDEHEKMNHVSELNKDLHDSLQLAPVIGEPSFVEFADSIVGRI 312

Query: 482  -QEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQM 540
             ++   +E  +E ++V  K   +  K    + T  +D+           KS+ K   K+ 
Sbjct: 313  DKDHEVEEEEEEEEEVEEKQAADVQKLKSHRDTDSDDDGAPLGNQTSPTKSSDKSSPKER 372

Query: 541  QKTIDNFSK-VSDSNKEIVRLTEELH-HLSQKVAELEEEKGNLQLHLVDYDSGRMIESDV 598
               ID   K ++++ K++    + L    +  V  L+      +  L +  +G  +E ++
Sbjct: 373  SDNIDELKKELAETEKKVQEKRDALDPTYAAMVYALKTAIEAKEQELENLQNGESVE-EL 431

Query: 599  YKKMIEMENLAETRLKAIS---LLESQKFDLVQELHILQ---QKYDEVEDKLADISQLQS 652
             KK+ ++E   E +    S    LE Q  +   EL  LQ    K +E   KL ++ +  +
Sbjct: 432  KKKLADVEKQIEEQKNKSSDNISLEHQLAEKQAELENLQNTPDKSEEFNQKLKELEKAIN 491

Query: 653  DQVC----SEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKD----LENDKE 704
            D++     ++ K+  L++ +D  +   + + +V +N +  ++QL   IKD    L+N+  
Sbjct: 492  DRLKQNSETDAKNKQLQDAVDNKNRELETITVVQDNSEELQKQL-NDIKDQIEKLKNNSN 550

Query: 705  DIMNKLQNYIQENMDLTDK--LEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDL 762
            ++ +KL N ++ N+D TDK  L+ ++ +    L  +I  + Q   + +  I   I +   
Sbjct: 551  ELTDKL-NELKSNID-TDKGVLDSLN-DNADVLNVQIEEKNQEYERLEDKIQELIADIAT 607

Query: 763  YIENIESELSKYKSRICRLEESIAVMEDRRYSLER---KADQLGSYLQEKQKAYSEYTIQ 819
              E +  + ++ + +  +L+E I  +E+R+   E+     D L   + EKQ+   E    
Sbjct: 608  KTEKVGEKDAQVEEKKAQLDELIKAIEERKNQSEQNNENNDSLQHQIDEKQRQLDELIKA 667

Query: 820  EDELVNRLAVLMDHDRVVEKQL----LEIEHENKEL-QKKNQILL--EENQNLQISLSDM 872
             +E  N+     +++  +++Q+     +++  NK + ++KNQ     E N +LQ  + + 
Sbjct: 668  IEERKNQSEQNKENNDSLQQQIDEKKAQLDELNKAIEERKNQSEQNNENNDSLQQQIDEK 727

Query: 873  QQHYNALV----EKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDL 928
            Q+  + L+    E+ N+++  +  +   Q Q+ + +  L+ I +       + K +++ L
Sbjct: 728  QRQLDELIKAIEERKNQSEQNKENNDSLQQQIDEKQRQLEAIKNIPDN-SEELKNQLQIL 786

Query: 929  EIEFNTQIESAIRDKKVLNEKYE---KNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMN 985
            E  FN ++E    + K L +  +   K +E   +++   +E K  ++++N  +E+    N
Sbjct: 787  EKAFNDKMEQNAANNKQLQDAIDSKKKELENTPEVQDNSEELKKQLDDINEQIEKRKNDN 846

Query: 986  LELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSD 1045
             EL DK  +  +          INE    +    +K+EE   L ++I + +    S+V  
Sbjct: 847  KELEDKLEELSKA---------INEQKLADEETAKKNEE---LEKQIKDKEAEKNSLV-P 893

Query: 1046 YESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMN 1105
             E K  +   KL ++E+++    ++  ++   N++L+  ++E+ +++ ELK   +  +  
Sbjct: 894  VEDKTEELARKLADLEKQIAEQLEKQNETDGKNKDLEQQIKEKQEKLDELKNNFIE-DTK 952

Query: 1106 IPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLN 1165
              + E   +   +  +    N +              K     +   +  +LQ+   +  
Sbjct: 953  EKENEIEELLQELNDLDSKINEIQDQISQFQEEYEEKKDHIVSDINTKDQLLQDLMEENL 1012

Query: 1166 TELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSIS 1225
             +L+E  T ++  E +++E    D +N +Q+  L  ++   + +  +L+   +++ + I+
Sbjct: 1013 KQLKE--TPVVAEEPIDSEAL--DKIN-DQMADLIERINSGDIDPSDLVEKESQMEALIN 1067

Query: 1226 SA-VDQRG------------FEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLL 1272
            +A VD  G             ++ E    +L + E +  + E E   + ++ E K + + 
Sbjct: 1068 NAIVDNHGNKELVKQLEDMRNKMGERIDDYLNEAEKEDLEEEEETIPEQNSVEEKQDTIE 1127

Query: 1273 DSVQSSTQEETNKIVTMEQVTS----LQNKLQDKEEHLRNLQEKYADVINQIEILRSEIE 1328
            D  Q  +Q++ + + ++E V S    +QNKL + E+ + + Q K  ++ N+ + L  ++ 
Sbjct: 1128 DLEQQLSQKQKD-LESIEPVESKKEEIQNKLNEIEKEINDKQAKNEEIKNENDALEQQLA 1186

Query: 1329 DEKVAFXX--XXXXXXXXXXXXXXDLRTE-NQSYKQMQEQSILNINEENAQLKKSSXXXX 1385
            ++K                     D+ ++ N+   + +E   +N   E+   +K      
Sbjct: 1187 EKKKELDSIPTVEDKTSDLESQLKDIESQINEKRAKNEETEKMNKEFEDKLAEKQQELDS 1246

Query: 1386 XXXXXXXXRVNDAEAKVLELTHQLELKDSE---------IYQKTHEYTITLTQRNDEFEN 1436
                       ++E+K  E     +L + E         I     +    ++   D    
Sbjct: 1247 IEEKAEEQTTPESESKEQEKEESKDLSELESKIRDLLERIAAGDKDPETLVSVSEDILST 1306

Query: 1437 VRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKIT 1496
            +  ++   +   + L Y++ SE   +   + +     E    + E E ++ +E  ++ + 
Sbjct: 1307 LNDKIATSDSDDDKLRYQQASE--TINNAVEQYLASLEDAYNDEEEEPIQEVETRDIILP 1364

Query: 1497 ESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQK 1556
            +  +   +  E ++  EE   KT+E+++ + + + EI     +  +L N +     ++ +
Sbjct: 1365 DEAA--NEGEEESQQSEELETKTDELKSQIADVDREIAEQKSKNDDLMNKINELQQQLAE 1422

Query: 1557 HVSFASDTKQGRDEQLDNTMNK 1578
              +   D+   +  +L+  ++K
Sbjct: 1423 KQN-VRDSLSAQTAELEEQLSK 1443



 Score =  101 bits (243), Expect = 1e-19
 Identities = 180/915 (19%), Positives = 390/915 (42%), Gaps = 94/915 (10%)

Query: 682  IENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINH 741
            ++NLKL+   L   I+D ++  ED+   + +    +  L ++ E   A+ ISEL AK+  
Sbjct: 3    LDNLKLENSALQSCIEDNKSAIEDLRRDVVSEEDLHSQLENEQEASFAD-ISELNAKL-- 59

Query: 742  EEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQ 801
                         A +Q  + ++  +  E SK  + I  +E SIA    R     +    
Sbjct: 60   -------------ASLQTDNSFLPEVSDEHSKLLADISAIESSIADKRSRNEETSKLNQA 106

Query: 802  LGSYLQEKQKAYSEYTIQEDE---LVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQIL 858
            L + L+ K+K  S     ED+   L N +  +         Q  E E +NKEL+++   +
Sbjct: 107  LEAELESKKKQLSFLPTVEDKSASLENEIKKVDSEINTKNSQNAETEKKNKELEEQLAKI 166

Query: 859  LEE-------NQNLQISLSDMQQ------HYNALVEKANRTDLAESESTKYQTQL-RDLE 904
             ++       N N     S + Q       +N   EKAN+ ++ + ++ K Q  +  + +
Sbjct: 167  QQDLDSIPSTNDNSHFLQSQIDQIINEHNSHNDEPEKANK-EIQQKDADKQQNNISTESD 225

Query: 905  SNLKRITHEHQTL-----IVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQ 959
             + K+ + +   L      +      +   IE N +IE    D++ +N+++EK + +V++
Sbjct: 226  ESSKQFSSDDLNLDGLLDDIAGGYRSDSSLIESNNEIED---DQQSVNDEHEK-MNHVSE 281

Query: 960  LEAQLQEYKNNIENL-NMNVEELNKMNLELIDK--HVQKQQTQSPDYTEQYINEINKLNA 1016
            L   L +       +   +  E     +  IDK   V++++ +  +  E+   ++ KL +
Sbjct: 282  LNKDLHDSLQLAPVIGEPSFVEFADSIVGRIDKDHEVEEEEEEEEEVEEKQAADVQKLKS 341

Query: 1017 LL-KQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQL---- 1071
                  D++   L  + +  + S  S   +    + +   +L   E+++Q     L    
Sbjct: 342  HRDTDSDDDGAPLGNQTSPTKSSDKSSPKERSDNIDELKKELAETEKKVQEKRDALDPTY 401

Query: 1072 ------LDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMI---ISSTIEPMS 1122
                  L +    +E ++   +  + ++ELK+     E  I + +      IS   +   
Sbjct: 402  AAMVYALKTAIEAKEQELENLQNGESVEELKKKLADVEKQIEEQKNKSSDNISLEHQLAE 461

Query: 1123 DDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECY-TKIIQLETL 1181
              A   +             K++E E+ I +R     ++   N +LQ+    K  +LET+
Sbjct: 462  KQAELENLQNTPDKSEEFNQKLKELEKAINDRLKQNSETDAKNKQLQDAVDNKNRELETI 521

Query: 1182 NTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISS--AVDQRGFEIAELW 1239
             T +  +    Q+Q+N +K ++E+L   ++ L   + EL+S+I +   V     + A++ 
Sbjct: 522  -TVVQDNSEELQKQLNDIKDQIEKLKNNSNELTDKLNELKSNIDTDKGVLDSLNDNADVL 580

Query: 1240 KQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKL 1299
               + ++  ++++ E +++  ++   +K E++ +      +++      ++ +   +N+ 
Sbjct: 581  NVQIEEKNQEYERLEDKIQELIADIATKTEKVGEKDAQVEEKKAQLDELIKAIEERKNQS 640

Query: 1300 QDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSY 1359
            +   E+  +LQ +  +   Q++ L   IE+ K                     +  N S 
Sbjct: 641  EQNNENNDSLQHQIDEKQRQLDELIKAIEERK---------------NQSEQNKENNDSL 685

Query: 1360 KQMQEQSILNINEENAQL---KKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEI 1416
            +Q  ++    ++E N  +   K  S            ++++ + ++ EL   +E + ++ 
Sbjct: 686  QQQIDEKKAQLDELNKAIEERKNQSEQNNENNDSLQQQIDEKQRQLDELIKAIEERKNQ- 744

Query: 1417 YQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRL----KMHENANH 1472
             ++  E   +L Q+ DE    +Q+ +E  K I D + E +++L IL      KM +NA +
Sbjct: 745  SEQNKENNDSLQQQIDE----KQRQLEAIKNIPDNSEELKNQLQILEKAFNDKMEQNAAN 800

Query: 1473 YETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALE--NQE 1530
             + +Q   + ++ +L     V+   S  L KQ+ ++N+ +E+      E++  LE  ++ 
Sbjct: 801  NKQLQDAIDSKKKELENTPEVQ-DNSEELKKQLDDINEQIEKRKNDNKELEDKLEELSKA 859

Query: 1531 IEIVTLNDEITNLQN 1545
            I    L DE T  +N
Sbjct: 860  INEQKLADEETAKKN 874



 Score = 66.9 bits (156), Expect = 4e-09
 Identities = 109/712 (15%), Positives = 297/712 (41%), Gaps = 53/712 (7%)

Query: 897  QTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEY 956
            ++ + DL  ++      H  L  +++    D+  E N ++ S   D   L E  +++   
Sbjct: 21   KSAIEDLRRDVVSEEDLHSQLENEQEASFADIS-ELNAKLASLQTDNSFLPEVSDEH--- 76

Query: 957  VTQLEAQLQEYKNNIENLNMNVEELNKMN--LELIDKHVQKQQTQSP---DYTEQYINEI 1011
             ++L A +   +++I +     EE +K+N  LE   +  +KQ +  P   D +    NEI
Sbjct: 77   -SKLLADISAIESSIADKRSRNEETSKLNQALEAELESKKKQLSFLPTVEDKSASLENEI 135

Query: 1012 NKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQL 1071
             K+++ +  K+ +     +K    +     +  D +S      +  +N      ++ + +
Sbjct: 136  KKVDSEINTKNSQNAETEKKNKELEEQLAKIQQDLDS----IPSTNDNSHFLQSQIDQII 191

Query: 1072 LDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXX 1131
             +   HN+E +   +E   +  + ++  ++ E +    +       ++ + DD       
Sbjct: 192  NEHNSHNDEPEKANKEIQQKDADKQQNNISTESDESSKQFSSDDLNLDGLLDDI--AGGY 249

Query: 1132 XXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQL-ETLNTELTGHDV 1190
                       +++++++ + +        ++LN +L +       + E    E     V
Sbjct: 250  RSDSSLIESNNEIEDDQQSVNDEHEKMNHVSELNKDLHDSLQLAPVIGEPSFVEFADSIV 309

Query: 1191 VNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIA-ELWKQHLAQREAD 1249
               ++ ++++ + E+     +   + V +L+S   +  D  G  +  +      + + + 
Sbjct: 310  GRIDKDHEVEEEEEEEEEVEEKQAADVQKLKSHRDTDSDDDGAPLGNQTSPTKSSDKSSP 369

Query: 1250 FQKTEH--ELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLR 1307
             +++++  EL+ +L+  E K ++  D++  +             V +L+  ++ KE+ L 
Sbjct: 370  KERSDNIDELKKELAETEKKVQEKRDALDPTYAA---------MVYALKTAIEAKEQELE 420

Query: 1308 NLQ--EKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQ-SYKQMQE 1364
            NLQ  E   ++  ++  +  +IE++K                   ++  E+Q + KQ + 
Sbjct: 421  NLQNGESVEELKKKLADVEKQIEEQK--------------NKSSDNISLEHQLAEKQAEL 466

Query: 1365 QSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSE------IYQ 1418
            +++ N  +++ +  +              + ++ +AK  +L   ++ K+ E      +  
Sbjct: 467  ENLQNTPDKSEEFNQKLKELEKAINDRLKQNSETDAKNKQLQDAVDNKNRELETITVVQD 526

Query: 1419 KTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQK 1478
             + E    L    D+ E ++    E   ++ +L    +++  +L   +++NA+      +
Sbjct: 527  NSEELQKQLNDIKDQIEKLKNNSNELTDKLNELKSNIDTDKGVLD-SLNDNADVLNVQIE 585

Query: 1479 ESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLND 1538
            E   E  +L +++   I +  +  ++V E +  +EE+ A+ +E+  A+E ++ +    N+
Sbjct: 586  EKNQEYERLEDKIQELIADIATKTEKVGEKDAQVEEKKAQLDELIKAIEERKNQSEQNNE 645

Query: 1539 EITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELD 1590
               +LQ+ +     ++ + +    + K   ++  +N  + +      +A+LD
Sbjct: 646  NNDSLQHQIDEKQRQLDELIKAIEERKNQSEQNKENNDSLQQQIDEKKAQLD 697


>UniRef50_A2ERL6 Cluster: Viral A-type inclusion protein, putative;
            n=1; Trichomonas vaginalis G3|Rep: Viral A-type inclusion
            protein, putative - Trichomonas vaginalis G3
          Length = 2832

 Score =  175 bits (426), Expect = 8e-42
 Identities = 284/1454 (19%), Positives = 615/1454 (42%), Gaps = 109/1454 (7%)

Query: 168  METTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIA 227
            + T I +LQ+++      I+AK K  +                      Q+  + +   A
Sbjct: 403  LNTKISNLQKELENAKDTIDAKQKKISTMYERMKAPLLEQNQKIN----QLESLIDTLNA 458

Query: 228  MEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXX 287
               + KD   +LLKD      RIS  ++ N  L+A   ++    +K+ +  ++       
Sbjct: 459  KNGKQKDSI-KLLKD------RISQFQDNNSKLQAKIAKLEAT-AKIHENEKETLNSKID 510

Query: 288  XXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELEN 347
                   + + +++   +    ++E        +T+ T+K + +   N   R+ N EL  
Sbjct: 511  YLSKENNIKEDTVKKVQDANQSLKEYKETATKQITDNTQKFQEILDENQSYREKNAELSR 570

Query: 348  KLATMGTE-SKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNE 406
            KL     +    ++  + K   +   K  +  A  +K    +L  E      + K+ KN+
Sbjct: 571  KLLESQKQIDDLINGFNDKDQQI---KGIKGEAGTVKQKIKELLDE------NSKL-KNK 620

Query: 407  IAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLI 466
            I++L+  ++  N     K+  +  ++            +D     L L+         + 
Sbjct: 621  ISELDQSLK--NSQTAQKQTTLKTQEQLKQNDSLQNILEDKNSELLSLKELNSTNENQIN 678

Query: 467  HVGT---NTEDVNEIAKVQEQLKQELNDEIKDVNVK-----DLIEKLKSAEEQITQLNDE 518
             + T   N +  N+  KV  Q   E NDE+++  +K     DLI++  + + Q+    +E
Sbjct: 679  KLKTKLDNLQKENDELKVSLQKVTERNDELENTTIKSDKANDLIQENMTLKSQMKDAKNE 738

Query: 519  IDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVS-DSNKEIVRLTEELHHLSQKVAE-LEE 576
                   M +++  ++L LKQ Q+ ++   K +  +N ++     ++   ++ V++ L +
Sbjct: 739  NAKTMNEMKQIQLENEL-LKQNQQNLEKEIKENIQNNLDLQNKLNKIEWDNKIVSDKLAK 797

Query: 577  EKGNLQLHLVDYDSGRMIESDVYKKMIEMENLA-ETRLKAISLLESQKFDLVQELHI-LQ 634
            EK +L+L   +  +   + ++ ++K+ E ENLA   +L  ++ L     D +Q   + LQ
Sbjct: 798  EKSSLELQNENLQNQNKLLNENHQKVTE-ENLAISQKLNDLNNLNKMCQDELQSTSLTLQ 856

Query: 635  QKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYG 694
            +K  E+ED    +  L+ +    + + + +E +I  L    K     +  +  DK+    
Sbjct: 857  RKEKELEDLKQKMENLEKEFYDVKTEKMSMENKIFDLEKESKNQNDNMNKIIEDKDL--- 913

Query: 695  TIKDLENDKEDIMNK---LQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQF 751
             IKDL    E +  +   LQN  +EN +L  + + +  E  +EL  KI+ + +   + + 
Sbjct: 914  QIKDLRTKNEKLTEENSNLQNKEKENKNLQSRNQIVEKEN-TELSQKISSQNERINELEN 972

Query: 752  GIDAKIQERDLYIENIESELSKYKSR-ICRLEESIAVMEDRRYSLERKADQLGSYLQEKQ 810
             +   +Q + L  ++   ++++  ++ +     S+  M  +   L+RK +++ + L EK 
Sbjct: 973  AVST-LQNQILENDDKSQKVTEQTAKDLIAANSSLKQMTYQNELLQRKQNEMENDLDEKS 1031

Query: 811  KAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLS 870
                +   + D+L   +  L + +R +     +I  EN  ++ + + + +EN++ +  L 
Sbjct: 1032 SRIKDLEDENDDLQKEILELQNENRKISSNYEKISKENNRIEMEMKQIKDENESNKQKLV 1091

Query: 871  DMQQHYNALVEKANRTDLAESESTKYQTQLRD---LESNLK-------RITHEHQTLIVQ 920
            D  + +    EK N  + A+S+ +K     +D   L SN+K       ++ +E+  L  +
Sbjct: 1092 DNTKKHEE--EKMNLINNAKSDKSKIDGLTKDISMLNSNIKLLQDENSKLDNENSQLENE 1149

Query: 921  KKKEIEDLE-----IEFNTQI-ESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENL 974
             KK  EDL+     I  N  + ++   + K L +K E   +   Q++  +Q+  N   +L
Sbjct: 1150 IKKLTEDLQKQNEKINDNQNLLQNVTNENKKLKDKNELLFKENEQIKNLMQDKINENNSL 1209

Query: 975  N-MNVEELNKMNLE-LIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKI 1032
                +E  N +N E L ++ +  +  +  ++ +   +   K NA L Q ++ +   N ++
Sbjct: 1210 KEKQIEMENDLNTEKLNNERLVGRLKEIENHNKSKKDNTAKENAKLTQNNKALANENFEL 1269

Query: 1033 NNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNE----ELQIL---- 1084
                 +    +SD ++K  + ++++   E+E+Q+ + +    K  NE    E+Q L    
Sbjct: 1270 KQKVANLDQELSDVKNKFDKMSSQISESEKEVQQNAAEFRQIKAKNESLNKEVQFLNDLV 1329

Query: 1085 --VREQDDQIKELKET-KLTFEMNIPKTEGMI--ISSTIEPMSDDANNVDXXXXXXXXXX 1139
              +++Q+D ++  KE    TF  +I      +  I +  E +  +   +           
Sbjct: 1330 TNLKQQNDDLRNKKEELNTTFSEDIDNISNELREIKTQNEFLRKENEEMKNQSQLTKADN 1389

Query: 1140 XXLKVQEE-EEFIQERSVLQ-EQSAKLNTELQECYTKIIQ-LETLNTELTGHDVVNQEQI 1196
              LK + + ++ I  +S+++  +  KLN ++ +   KI   L+ L  E   +D    E I
Sbjct: 1390 DKLKEENQNQKEINTKSLMKINELEKLNKQINDEMAKIQNNLQNLTQEKEENDSKQDEII 1449

Query: 1197 NQLKSKLEQLNTENDNLLSTVAELRSSIS------SAVDQRGFEIAELWKQHLAQREADF 1250
             + + + E L +EN N  + +  L             V +   ++AE  K      E   
Sbjct: 1450 KEYEQENETLRSENQNFETKIKVLEKENKLNVFSLQKVTKEKEDLAEKLKNQKEVNET-L 1508

Query: 1251 QKTEHELRVQ---LSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLR 1307
            +K + +L  +   L   E K +Q+L S   + +++ N +   ++   L N+  D ++  +
Sbjct: 1509 EKAKEDLETENNNLKLNEDKIKQIL-SENENLKQKLNDL--QKENNDLVNESNDIKQKQK 1565

Query: 1308 NLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSI 1367
               E   +  NQ E L +++ D +  F                +   +   +  +   ++
Sbjct: 1566 EEMESSKENQNQKEKLENDLNDLQKNFDELQKSYSDLLEKYKAENDQKESQFNNVNS-NL 1624

Query: 1368 LNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTH---QLELKDSEIYQKTHEYT 1424
               N +N  L++              +++  + +  EL +    +++++S     + +  
Sbjct: 1625 KQSNYQNDLLQRKLKDLEEEMKNDKEKIDTLQNRNEELENLFGNMKIENSSALANSDK-- 1682

Query: 1425 ITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIER 1484
              LT+ N+  ++    L +    I     E   EL  ++  + EN N YE + KE    +
Sbjct: 1683 --LTKENEALKSENLSLKQTNNEITTKNKELSIELEKIKQNLEENQNSYENVFKEKSDIK 1740

Query: 1485 VKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQ 1544
             KL ++L  +  +  + NK + +  + LEE   K N+ +  +EN   ++  L  +   L+
Sbjct: 1741 EKL-DQLIQETNDQKAANKNLLKEKETLEE-TQKQNQKE--IENLIQKVTKLKAKNDFLK 1796

Query: 1545 NMVRASSSKIQKHV 1558
              +  S SK+Q  +
Sbjct: 1797 ENITESKSKLQGEI 1810



 Score =  175 bits (426), Expect = 8e-42
 Identities = 288/1467 (19%), Positives = 636/1467 (43%), Gaps = 115/1467 (7%)

Query: 148  SNTIKEKDNALSVLQVKMKIMETTILDLQ-EKINEKDQI--IEAKNKATTXXXXXXXXXX 204
            S T++ K+  L  L+ KM+ +E    D++ EK++ +++I  +E ++K             
Sbjct: 852  SLTLQRKEKELEDLKQKMENLEKEFYDVKTEKMSMENKIFDLEKESKNQNDNMNKIIEDK 911

Query: 205  XXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISS-LEEANKLLEAA 263
                       +++T+   N    E E K+ + R  + +E ++  +S  +   N+ +   
Sbjct: 912  DLQIKDLRTKNEKLTEENSNLQNKEKENKNLQSRN-QIVEKENTELSQKISSQNERINEL 970

Query: 264  RFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTE 323
               +S   +++ +  +                A  S++    +   ++ K +    ++ E
Sbjct: 971  ENAVSTLQNQILEN-DDKSQKVTEQTAKDLIAANSSLKQMTYQNELLQRKQNEMENDLDE 1029

Query: 324  LTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMK 383
             + +I+ LE  N  +++   EL+N+   + +  + +S  + +    + +    N ++K K
Sbjct: 1030 KSSRIKDLEDENDDLQKEILELQNENRKISSNYEKISKENNRIEMEMKQIKDENESNKQK 1089

Query: 384  --SPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXX 441
                  +   E +N   + K +K++I  L   I  LN ++   + +  E           
Sbjct: 1090 LVDNTKKHEEEKMNLINNAKSDKSKIDGLTKDISMLNSNI---KLLQDENSKLDNENSQL 1146

Query: 442  XXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDL 501
                  L   LQ ++++  +  +L+   TN    N+  K + +L  + N++IK++ ++D 
Sbjct: 1147 ENEIKKLTEDLQKQNEKINDNQNLLQNVTNE---NKKLKDKNELLFKENEQIKNL-MQDK 1202

Query: 502  IEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLT 561
            I +  S +E+  ++ ++++    N  ++      +LK+++    N SK  ++ KE  +LT
Sbjct: 1203 INENNSLKEKQIEMENDLNTEKLNNERLVG----RLKEIEN--HNKSKKDNTAKENAKLT 1256

Query: 562  EELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLES 621
            +    L+ +  EL+++  NL   L          SDV  K  +M +      K +    +
Sbjct: 1257 QNNKALANENFELKQKVANLDQEL----------SDVKNKFDKMSSQISESEKEVQQNAA 1306

Query: 622  QKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVH--LEEQIDALSASKKELA 679
            +   +  +   L ++   + D + ++ Q Q+D + ++ + ++    E ID +S   +E+ 
Sbjct: 1307 EFRQIKAKNESLNKEVQFLNDLVTNLKQ-QNDDLRNKKEELNTTFSEDIDNISNELREIK 1365

Query: 680  LVIENLKLDKEQL--YGTIKDLENDKEDIMNKLQNYIQ-ENMDLTDKLEKMSAEKISELL 736
               E L+ + E++     +   +NDK    N+ Q  I  +++   ++LEK++ ++I++ +
Sbjct: 1366 TQNEFLRKENEEMKNQSQLTKADNDKLKEENQNQKEINTKSLMKINELEKLN-KQINDEM 1424

Query: 737  AKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLE 796
            AKI +  Q+  Q +   D+K   +D  I+  E E    +S     E  I V+E       
Sbjct: 1425 AKIQNNLQNLTQEKEENDSK---QDEIIKEYEQENETLRSENQNFETKIKVLE------- 1474

Query: 797  RKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKEL---QK 853
             K ++L  +  +K       T ++++L  +L    + +  +EK   ++E EN  L   + 
Sbjct: 1475 -KENKLNVFSLQK------VTKEKEDLAEKLKNQKEVNETLEKAKEDLETENNNLKLNED 1527

Query: 854  KNQILLEENQNLQISLSDMQQHYNALVEKAN---RTDLAESEST--------KYQTQLRD 902
            K + +L EN+NL+  L+D+Q+  N LV ++N   +    E ES+        K +  L D
Sbjct: 1528 KIKQILSENENLKQKLNDLQKENNDLVNESNDIKQKQKEEMESSKENQNQKEKLENDLND 1587

Query: 903  LESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYE---KNIEYVTQ 959
            L+ N   +   +  L+ + K E +  E +FN  + S ++     N+  +   K++E   +
Sbjct: 1588 LQKNFDELQKSYSDLLEKYKAENDQKESQFN-NVNSNLKQSNYQNDLLQRKLKDLEEEMK 1646

Query: 960  LEAQ----LQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPD--YTEQYINEINK 1013
             + +    LQ     +ENL  N++  N   L   DK  ++ +    +    +Q  NEI  
Sbjct: 1647 NDKEKIDTLQNRNEELENLFGNMKIENSSALANSDKLTKENEALKSENLSLKQTNNEITT 1706

Query: 1014 LNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRV--SKQL 1071
             N  L  + E+I    ++  N+  +     SD + KL Q   +  + +   + +   K+ 
Sbjct: 1707 KNKELSIELEKIKQNLEENQNSYENVFKEKSDIKEKLDQLIQETNDQKAANKNLLKEKET 1766

Query: 1072 LD--SKQHNEELQILVRE------QDDQIKE-LKETKLTFEMNIPKTEGMIISSTIEPMS 1122
            L+   KQ+ +E++ L+++      ++D +KE + E+K   +  I K +  +  +T+   S
Sbjct: 1767 LEETQKQNQKEIENLIQKVTKLKAKNDFLKENITESKSKLQGEIIKLKEDL--ATMTQKS 1824

Query: 1123 DDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLN 1182
            ++                   +   +   +    L+++   L  E  E   +I Q+    
Sbjct: 1825 NEEKQAQENELSNLKIEHEHLINNFDLLTKGNENLKQKIGNLTQENMESKKEIAQILLEK 1884

Query: 1183 TELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQH 1242
            T L   +   Q +I  L+  +E+   ++  + S   ++ S + + +++   E  E   Q 
Sbjct: 1885 TTLQNQNDSLQNEIENLEKTIEKQKQDSVEIKSKFDQMLSEMKNKMEKNKAENDEK-LQK 1943

Query: 1243 LAQREADFQKTEHELRVQLSAFESKYEQLLDSV-------QSSTQEETNKIVTMEQVT-- 1293
            + + +++ QK   E+R +++  + + +++ ++        +S  +E+  K + +E+V+  
Sbjct: 1944 VEEEKSNLQKENEEIREKINKLQEENDEMKENFNESQIMNESFAKEDNEKSLYIEKVSKQ 2003

Query: 1294 --SLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXD 1351
               LQN L+   +  +NL ++  ++ N  E L+SE +  +  F                 
Sbjct: 2004 NAELQNDLKQLTKENKNLAKQNENLKNSFEKLKSETDILQKNF-DDLQTKFNDLFDDNEQ 2062

Query: 1352 LRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLEL 1411
              +E +  K    +    INE+  QL  +              +   E KV E    L  
Sbjct: 2063 KASELEVVKSENSKQFAKINEQKQQL-DNLIKENSSLKVRNELIAKNEQKVSEENENLRT 2121

Query: 1412 KDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENAN 1471
            ++ ++ ++  EY     +++   +N  ++L      ++     K +E   L+  M+ N  
Sbjct: 2122 ENEKMKKEIIEY----DEKSQILQNENKKLSLLNDNLQKDLQNKITENDNLK-NMNSNLK 2176

Query: 1472 HYET-MQKESEI--ERVKLIE-ELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALE 1527
            + +T +  +SEI   ++K I   LN   +E+ SL K+   L +  ++  ++     + LE
Sbjct: 2177 NDKTNLGNKSEIFENQIKEISASLNKLKSENESLEKEKESLTEENKKLKSENQSQSSELE 2236

Query: 1528 NQEIEIVTLNDEITNLQNMVRASSSKI 1554
              + E  ++ +E+  L N     + KI
Sbjct: 2237 KVKSENTSMKNEVEKLANEKSELNKKI 2263



 Score =  174 bits (424), Expect = 1e-41
 Identities = 316/1509 (20%), Positives = 628/1509 (41%), Gaps = 141/1509 (9%)

Query: 144  VTHLSNTIKEKDNALSVLQVKMKIM--ETTIL-DLQEKINEKDQIIEAKNKATTXXXXXX 200
            +  L  T K  +N    L  K+  +  E  I  D  +K+ + +Q ++   +  T      
Sbjct: 488  IAKLEATAKIHENEKETLNSKIDYLSKENNIKEDTVKKVQDANQSLKEYKETATKQITDN 547

Query: 201  XXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLE-EANKL 259
                       +  +++  ++    +  + +  D    L+     KD +I  ++ EA  +
Sbjct: 548  TQKFQEILDENQSYREKNAELSRKLLESQKQIDD----LINGFNDKDQQIKGIKGEAGTV 603

Query: 260  LEAARFEISLEHSKLAQ---ELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSL 316
             +  + E+  E+SKL     EL+Q                ++ ++ +   +  +E+K S 
Sbjct: 604  KQKIK-ELLDENSKLKNKISELDQSLKNSQTAQKQTTLKTQEQLKQNDSLQNILEDKNS- 661

Query: 317  EIANMTELTK----KIELLEHLNCQIRQTNKELE---NKLATMGTESKAVSSPSKKGSPL 369
            E+ ++ EL      +I  L+     +++ N EL+    K+     E +  +  S K + L
Sbjct: 662  ELLSLKELNSTNENQINKLKTKLDNLQKENDELKVSLQKVTERNDELENTTIKSDKANDL 721

Query: 370  ISR--------KSGRNTASKMKSPWSQ--LSSETLNQDT---DKKINKNEIAKLEMVIQS 416
            I          K  +N  +K  +   Q  L +E L Q+    +K+I +N    L++    
Sbjct: 722  IQENMTLKSQMKDAKNENAKTMNEMKQIQLENELLKQNQQNLEKEIKENIQNNLDLQ-NK 780

Query: 417  LNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHME-GPSLIHVGTNTEDV 475
            LNK   D + V    D             + L  Q +L ++ H +     + +     D+
Sbjct: 781  LNKIEWDNKIV---SDKLAKEKSSLELQNENLQNQNKLLNENHQKVTEENLAISQKLNDL 837

Query: 476  NEIAKV-QEQLKQ-ELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNH 533
            N + K+ Q++L+   L  + K+  ++DL +K+++ E++   +  E  +    +  ++   
Sbjct: 838  NNLNKMCQDELQSTSLTLQRKEKELEDLKQKMENLEKEFYDVKTEKMSMENKIFDLEKES 897

Query: 534  KLKLKQMQKTI-DNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGR 592
            K +   M K I D   ++ D   +  +LTEE  +L  K    E+E  NLQ          
Sbjct: 898  KNQNDNMNKIIEDKDLQIKDLRTKNEKLTEENSNLQNK----EKENKNLQSR-------- 945

Query: 593  MIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADIS-QLQ 651
                    +++E EN  E   K IS    +  +L   +  LQ +  E +DK   ++ Q  
Sbjct: 946  -------NQIVEKEN-TELSQK-ISSQNERINELENAVSTLQNQILENDDKSQKVTEQTA 996

Query: 652  SDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQ 711
             D + +      +  Q + L   + E+    EN   D ++    IKDLE++ +D+  ++ 
Sbjct: 997  KDLIAANSSLKQMTYQNELLQRKQNEM----EN---DLDEKSSRIKDLEDENDDLQKEIL 1049

Query: 712  NYIQENMDLTDKLEKMSAE--KISELLAKINHEEQSKIQTQFGIDAKIQERDL-YIENIE 768
                EN  ++   EK+S E  +I   + +I  E +S  Q       K +E  +  I N +
Sbjct: 1050 ELQNENRKISSNYEKISKENNRIEMEMKQIKDENESNKQKLVDNTKKHEEEKMNLINNAK 1109

Query: 769  SELSKYKSR---ICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVN 825
            S+ SK       I  L  +I +++D       K D   S L+ + K  +E   +++E +N
Sbjct: 1110 SDKSKIDGLTKDISMLNSNIKLLQDEN----SKLDNENSQLENEIKKLTEDLQKQNEKIN 1165

Query: 826  RLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKA-- 883
                  D+  +++     + +ENK+L+ KN++L +EN+ ++  + D     N+L EK   
Sbjct: 1166 ------DNQNLLQN----VTNENKKLKDKNELLFKENEQIKNLMQDKINENNSLKEKQIE 1215

Query: 884  --NRTDLAESESTKYQTQLRDLESNLKRI---THEHQTLIVQKKKEIEDLEIEFNTQIES 938
              N  +  +  + +   +L+++E++ K     T +    + Q  K + +   E   ++ +
Sbjct: 1216 MENDLNTEKLNNERLVGRLKEIENHNKSKKDNTAKENAKLTQNNKALANENFELKQKVAN 1275

Query: 939  AIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQT 998
              ++   +  K++K    +++ E ++Q+       +    E LNK  ++ ++  V   + 
Sbjct: 1276 LDQELSDVKNKFDKMSSQISESEKEVQQNAAEFRQIKAKNESLNK-EVQFLNDLVTNLKQ 1334

Query: 999  QSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLE 1058
            Q+ D      N+  +LN    +  + I    ++I   Q  ++   ++ E K     TK +
Sbjct: 1335 QNDDLR----NKKEELNTTFSEDIDNISNELREIKT-QNEFLRKENE-EMKNQSQLTKAD 1388

Query: 1059 N--MEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKET--KLTFEM--NIPKTEGM 1112
            N  ++EE Q   +    S     EL+ L ++ +D++ +++     LT E   N  K + +
Sbjct: 1389 NDKLKEENQNQKEINTKSLMKINELEKLNKQINDEMAKIQNNLQNLTQEKEENDSKQDEI 1448

Query: 1113 I--ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQE 1170
            I       E +  +  N +            L V   ++  +E+  L E+  K   E+ E
Sbjct: 1449 IKEYEQENETLRSENQNFETKIKVLEKENK-LNVFSLQKVTKEKEDLAEK-LKNQKEVNE 1506

Query: 1171 CYTKIIQ-LETLNTELT-GHDVVNQ--EQINQLKSKLEQLNTENDNLLSTVAELRSSISS 1226
               K  + LET N  L    D + Q   +   LK KL  L  EN++L++   +++     
Sbjct: 1507 TLEKAKEDLETENNNLKLNEDKIKQILSENENLKQKLNDLQKENNDLVNESNDIKQKQKE 1566

Query: 1227 AVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKI 1286
             ++    +  +  K+ L     D QK   EL+   S    KY+   D  +S      + +
Sbjct: 1567 EMESS--KENQNQKEKLENDLNDLQKNFDELQKSYSDLLEKYKAENDQKESQFNNVNSNL 1624

Query: 1287 VTME-QVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXX 1345
                 Q   LQ KL+D EE ++N +EK   + N+ E L +   + K+             
Sbjct: 1625 KQSNYQNDLLQRKLKDLEEEMKNDKEKIDTLQNRNEELENLFGNMKIENSSALANSDKLT 1684

Query: 1346 XXXXXDLRTENQSYKQMQEQSILNINE---ENAQLKKSSXXXXXXXXXXXXRVNDAEAKV 1402
                  L++EN S KQ   +      E   E  ++K++               +D + K+
Sbjct: 1685 KENEA-LKSENLSLKQTNNEITTKNKELSIELEKIKQNLEENQNSYENVFKEKSDIKEKL 1743

Query: 1403 LEL---THQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKR---IEDLTYEKE 1456
             +L   T+  +  +  + ++      T  Q   E EN+ Q++ + + +   +++   E +
Sbjct: 1744 DQLIQETNDQKAANKNLLKEKETLEETQKQNQKEIENLIQKVTKLKAKNDFLKENITESK 1803

Query: 1457 SELAILRLKMHENANHYETMQKESEIERVKLIEEL-NVKITESVSLNK--QVAELNKALE 1513
            S+L    +K+ E+     TM ++S  E+     EL N+KI     +N    + + N+ L+
Sbjct: 1804 SKLQGEIIKLKEDL---ATMTQKSNEEKQAQENELSNLKIEHEHLINNFDLLTKGNENLK 1860

Query: 1514 EEVAKTNE--MQTALENQEI--EIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRD 1569
            +++    +  M++  E  +I  E  TL ++  +LQN +      I+K    + + K   D
Sbjct: 1861 QKIGNLTQENMESKKEIAQILLEKTTLQNQNDSLQNEIENLEKTIEKQKQDSVEIKSKFD 1920

Query: 1570 EQLDNTMNK 1578
            + L    NK
Sbjct: 1921 QMLSEMKNK 1929



 Score =  161 bits (392), Expect = 1e-37
 Identities = 307/1512 (20%), Positives = 620/1512 (41%), Gaps = 168/1512 (11%)

Query: 212  EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271
            +  K  M +M+   +  E  +++E  +L  +I S       LEE NKLLE +  +I  E 
Sbjct: 225  QQLKDSMKEMRATSLEKEKRFQEEILKLKDEIRSLQDNNKMLEEQNKLLEESVKDIHTES 284

Query: 272  SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIA-NMTE-----LT 325
              + +                  L  + IE          E      A + TE     L 
Sbjct: 285  QNILENDNDTIKLNQELAVKDAQLEAKDIEILKLRNALYTENQKFTTAYSQTENRDSPLA 344

Query: 326  KKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSP 385
            ++I+ L     Q++  N   + KL     +   +     +    + R    N   K K  
Sbjct: 345  EEIKTLTLTMSQLKDENTRNQEKLKKFKDDKLKLKQALHQNE--LDRVKDEN---KYKPQ 399

Query: 386  WSQLSSETLNQDTDKKINKNEI----AKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXX 441
             + L+++  N   + +  K+ I     K+  + + +   L+++   I++ ++        
Sbjct: 400  INDLNTKISNLQKELENAKDTIDAKQKKISTMYERMKAPLLEQNQKINQLESLIDTLNAK 459

Query: 442  XXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEI----KDVN 497
               +   I  L+    Q  +  S +        +   AK+ E  K+ LN +I    K+ N
Sbjct: 460  NGKQKDSIKLLKDRISQFQDNNSKLQ--AKIAKLEATAKIHENEKETLNSKIDYLSKENN 517

Query: 498  VK-DLIEKLKSAEEQI--------------TQLNDEIDAANKNMIKVKSNHKLKLKQMQK 542
            +K D ++K++ A + +              TQ   EI   N++  +  +    KL + QK
Sbjct: 518  IKEDTVKKVQDANQSLKEYKETATKQITDNTQKFQEILDENQSYREKNAELSRKLLESQK 577

Query: 543  TIDN-FSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSG---------- 591
             ID+  +  +D +++I  +  E   + QK+ EL +E   L+  + + D            
Sbjct: 578  QIDDLINGFNDKDQQIKGIKGEAGTVKQKIKELLDENSKLKNKISELDQSLKNSQTAQKQ 637

Query: 592  -------RMIESDVYKKMIEMENLAETRLKAI-SLLESQKFDLVQELHILQQKYDEVEDK 643
                   ++ ++D  + ++E +N     LK + S  E+Q   L  +L  LQ++ DE++  
Sbjct: 638  TTLKTQEQLKQNDSLQNILEDKNSELLSLKELNSTNENQINKLKTKLDNLQKENDELKVS 697

Query: 644  LADISQLQSDQVCSEIKS----------VHLEEQI-DALSAS------KKELALVIENLK 686
            L  +++   +   + IKS          + L+ Q+ DA + +       K++ L  E LK
Sbjct: 698  LQKVTERNDELENTTIKSDKANDLIQENMTLKSQMKDAKNENAKTMNEMKQIQLENELLK 757

Query: 687  LDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKL--EKMSAEKISELLAK----IN 740
             +++ L   IK+   +  D+ NKL     +N  ++DKL  EK S E  +E L      +N
Sbjct: 758  QNQQNLEKEIKENIQNNLDLQNKLNKIEWDNKIVSDKLAKEKSSLELQNENLQNQNKLLN 817

Query: 741  HEEQSKIQTQFGIDAK--------------IQERDLYIENIESELSKYKSRICRLEESIA 786
               Q   +    I  K              +Q   L ++  E EL   K ++  LE+   
Sbjct: 818  ENHQKVTEENLAISQKLNDLNNLNKMCQDELQSTSLTLQRKEKELEDLKQKMENLEKEFY 877

Query: 787  VMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEH 846
             ++  + S+E K   L    + +    ++    +D  +  L    +        L   E 
Sbjct: 878  DVKTEKMSMENKIFDLEKESKNQNDNMNKIIEDKDLQIKDLRTKNEKLTEENSNLQNKEK 937

Query: 847  ENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKAN--RTDLAESE--STKYQTQ-LR 901
            ENK LQ +NQI+ +EN  L   +S   +  N L    +  +  + E++  S K   Q  +
Sbjct: 938  ENKNLQSRNQIVEKENTELSQKISSQNERINELENAVSTLQNQILENDDKSQKVTEQTAK 997

Query: 902  DL---ESNLKRITHEHQTL----------IVQKKKEIEDLEIEFNTQIESAIRDKKVLNE 948
            DL    S+LK++T++++ L          + +K   I+DLE E N  ++  I + +  N 
Sbjct: 998  DLIAANSSLKQMTYQNELLQRKQNEMENDLDEKSSRIKDLEDE-NDDLQKEILELQNENR 1056

Query: 949  KYEKNIEYVT----QLEAQLQEYK----NNIENLNMNVEELNKMNLELIDKHVQKQQTQS 1000
            K   N E ++    ++E ++++ K    +N + L  N ++  +  + LI+    K     
Sbjct: 1057 KISSNYEKISKENNRIEMEMKQIKDENESNKQKLVDNTKKHEEEKMNLINN--AKSDKSK 1114

Query: 1001 PDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENM 1060
             D   + I+ +N    LL+ ++ ++   N ++ N        +     K+      L+N+
Sbjct: 1115 IDGLTKDISMLNSNIKLLQDENSKLDNENSQLENEIKKLTEDLQKQNEKINDNQNLLQNV 1174

Query: 1061 EEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEP 1120
              E +++  +     + NE+++ L++++ ++   LKE ++  E ++  TE +     +  
Sbjct: 1175 TNENKKLKDKNELLFKENEQIKNLMQDKINENNSLKEKQIEMENDL-NTEKLNNERLVGR 1233

Query: 1121 MSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLET 1180
            + +  N+              L  Q  +    E   L+++ A L+ EL +   K  ++ +
Sbjct: 1234 LKEIENHNKSKKDNTAKENAKL-TQNNKALANENFELKQKVANLDQELSDVKNKFDKMSS 1292

Query: 1181 LNTELTGHDVVNQEQINQLKSKLEQLNTE--------------NDNLLSTVAELRSSISS 1226
              +E       N  +  Q+K+K E LN E              ND+L +   EL ++ S 
Sbjct: 1293 QISESEKEVQQNAAEFRQIKAKNESLNKEVQFLNDLVTNLKQQNDDLRNKKEELNTTFSE 1352

Query: 1227 AVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKI 1286
             +D    E+ E+  Q+   R     K   E++ Q    ++  ++L +  Q+  +  T  +
Sbjct: 1353 DIDNISNELREIKTQNEFLR-----KENEEMKNQSQLTKADNDKLKEENQNQKEINTKSL 1407

Query: 1287 VTMEQVTSLQNKLQDK----EEHLRNL-QEKYADVINQIEILRS-EIEDEKVA-----FX 1335
            + + ++  L  ++ D+    + +L+NL QEK  +   Q EI++  E E+E +      F 
Sbjct: 1408 MKINELEKLNKQINDEMAKIQNNLQNLTQEKEENDSKQDEIIKEYEQENETLRSENQNFE 1467

Query: 1336 XXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRV 1395
                            L+   +  + + E+ + N  E N  L+K+             ++
Sbjct: 1468 TKIKVLEKENKLNVFSLQKVTKEKEDLAEK-LKNQKEVNETLEKAK--EDLETENNNLKL 1524

Query: 1396 NDAEAK-VLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYE 1454
            N+ + K +L     L+ K +++ ++ ++    L   +++ +  +++ +E  K  ++   +
Sbjct: 1525 NEDKIKQILSENENLKQKLNDLQKENND----LVNESNDIKQKQKEEMESSKENQNQKEK 1580

Query: 1455 KESELAILRLKMHENANHYETMQKESEIE---RVKLIEELNVKITESVSLNKQVAELNKA 1511
             E++L  L+    E    Y  + ++ + E   +      +N  + +S   N  +    K 
Sbjct: 1581 LENDLNDLQKNFDELQKSYSDLLEKYKAENDQKESQFNNVNSNLKQSNYQNDLLQRKLKD 1640

Query: 1512 LEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQ 1571
            LEEE+    E    L+N+  E+  L   +    +   A+S K+ K  + A  ++    +Q
Sbjct: 1641 LEEEMKNDKEKIDTLQNRNEELENLFGNMKIENSSALANSDKLTKE-NEALKSENLSLKQ 1699

Query: 1572 LDN---TMNKEL 1580
             +N   T NKEL
Sbjct: 1700 TNNEITTKNKEL 1711



 Score =  157 bits (380), Expect = 3e-36
 Identities = 300/1428 (21%), Positives = 603/1428 (42%), Gaps = 146/1428 (10%)

Query: 234  DEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXX 293
            +  ++ LKD   K++R +SLE+  +  E        E  KL  E+ +             
Sbjct: 221  ESTEQQLKD-SMKEMRATSLEKEKRFQE--------EILKLKDEI-RSLQDNNKMLEEQN 270

Query: 294  XLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMG 353
             L ++S++    E   I E  +  I    EL  K   LE  + +I +    L N L T  
Sbjct: 271  KLLEESVKDIHTESQNILENDNDTIKLNQELAVKDAQLEAKDIEILK----LRNALYTEN 326

Query: 354  TE-SKAVSSPSKKGSPLISR-KSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLE 411
             + + A S    + SPL    K+   T S++K         T NQ+  KK  K++  KL+
Sbjct: 327  QKFTTAYSQTENRDSPLAEEIKTLTLTMSQLKD------ENTRNQEKLKKF-KDDKLKLK 379

Query: 412  MVIQSLNKDLVDKEYV----ISEKDTXXXXXXXXXXG-KDTLIA-QLQLEHQ-QHMEGPS 464
              +     D V  E      I++ +T            KDT+ A Q ++    + M+ P 
Sbjct: 380  QALHQNELDRVKDENKYKPQINDLNTKISNLQKELENAKDTIDAKQKKISTMYERMKAPL 439

Query: 465  LIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANK 524
            L       + +N++    E L   LN   K+   KD I+ LK    Q    N ++ A   
Sbjct: 440  L----EQNQKINQL----ESLIDTLN--AKNGKQKDSIKLLKDRISQFQDNNSKLQAKIA 489

Query: 525  NMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAE-----LEEEKG 579
             +      H+ + + +   ID  SK ++  ++ V+  ++ +   ++  E     + +   
Sbjct: 490  KLEATAKIHENEKETLNSKIDYLSKENNIKEDTVKKVQDANQSLKEYKETATKQITDNTQ 549

Query: 580  NLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDE 639
              Q  L +  S R   +++ +K++E +   +  +   +  + Q   +  E   ++QK  E
Sbjct: 550  KFQEILDENQSYREKNAELSRKLLESQKQIDDLINGFNDKDQQIKGIKGEAGTVKQKIKE 609

Query: 640  VEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDL 699
            + D+ + +    S+   S   S   ++Q    +  + +    ++N+  DK     ++K+L
Sbjct: 610  LLDENSKLKNKISELDQSLKNSQTAQKQTTLKTQEQLKQNDSLQNILEDKNSELLSLKEL 669

Query: 700  ENDKEDIMNKLQ----NYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDA 755
             +  E+ +NKL+    N  +EN +L   L+K++ E+  EL       +++    Q  +  
Sbjct: 670  NSTNENQINKLKTKLDNLQKENDELKVSLQKVT-ERNDELENTTIKSDKANDLIQENMTL 728

Query: 756  KIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKAD-QLGSYLQEK-QKAY 813
            K Q +D   EN ++ +++ K    +LE  +     +    E K + Q    LQ K  K  
Sbjct: 729  KSQMKDAKNENAKT-MNEMKQ--IQLENELLKQNQQNLEKEIKENIQNNLDLQNKLNKIE 785

Query: 814  SEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQ 873
             +  I  D+L    + L       E Q   ++++NK L + +Q + EEN  +   L+D+ 
Sbjct: 786  WDNKIVSDKLAKEKSSL-------ELQNENLQNQNKLLNENHQKVTEENLAISQKLNDLN 838

Query: 874  QHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEF- 932
                   ++   T L      K    L+    NL++  ++ +T  +  + +I DLE E  
Sbjct: 839  NLNKMCQDELQSTSLTLQRKEKELEDLKQKMENLEKEFYDVKTEKMSMENKIFDLEKESK 898

Query: 933  --NTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELID 990
              N  +   I DK +  +      E +T+  + LQ  +   +NL    + + K N EL  
Sbjct: 899  NQNDNMNKIIEDKDLQIKDLRTKNEKLTEENSNLQNKEKENKNLQSRNQIVEKENTELSQ 958

Query: 991  K------HVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMV- 1043
            K       + + +        Q +   +K   + +Q  +++IA N  +   Q++Y + + 
Sbjct: 959  KISSQNERINELENAVSTLQNQILENDDKSQKVTEQTAKDLIAANSSLK--QMTYQNELL 1016

Query: 1044 ----SDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQI---LVREQDDQIK-EL 1095
                ++ E+ L + +++++++E+E   + K++L+ +  N ++      + +++++I+ E+
Sbjct: 1017 QRKQNEMENDLDEKSSRIKDLEDENDDLQKEILELQNENRKISSNYEKISKENNRIEMEM 1076

Query: 1096 KETKLTFEMNIPKTEGMIISSTIEPMS------DDANNVDXXXXXXXXXXXXLKVQEEE- 1148
            K+ K   E N  K          E M+       D + +D            +K+ ++E 
Sbjct: 1077 KQIKDENESNKQKLVDNTKKHEEEKMNLINNAKSDKSKIDGLTKDISMLNSNIKLLQDEN 1136

Query: 1149 -EFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHD----------------VV 1191
             +   E S L+ +  KL  +LQ+   KI   + L   +T  +                + 
Sbjct: 1137 SKLDNENSQLENEIKKLTEDLQKQNEKINDNQNLLQNVTNENKKLKDKNELLFKENEQIK 1196

Query: 1192 N--QEQINQ---LKSKL----EQLNTE---NDNLLSTVAELRSSISSAVDQRGFEIAELW 1239
            N  Q++IN+   LK K       LNTE   N+ L+  + E+ +   S  D    E A+L 
Sbjct: 1197 NLMQDKINENNSLKEKQIEMENDLNTEKLNNERLVGRLKEIENHNKSKKDNTAKENAKLT 1256

Query: 1240 KQH--LAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQN 1297
            + +  LA    + ++    L  +LS  ++K++++   +  S +E         Q+ + +N
Sbjct: 1257 QNNKALANENFELKQKVANLDQELSDVKNKFDKMSSQISESEKEVQQNAAEFRQIKA-KN 1315

Query: 1298 KLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQ 1357
            +  +KE    N      D++  ++    ++ ++K                   +++T+N+
Sbjct: 1316 ESLNKEVQFLN------DLVTNLKQQNDDLRNKKEELNTTFSEDIDNISNELREIKTQNE 1369

Query: 1358 ----SYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKD 1413
                  ++M+ QS L    +N +LK+ +            ++N+ E    +L  Q+  + 
Sbjct: 1370 FLRKENEEMKNQSQLT-KADNDKLKEENQNQKEINTKSLMKINELE----KLNKQINDEM 1424

Query: 1414 SEIYQKTHEYTITLTQRNDEFENVRQQLV-EYEKRIEDLTYEKESELAILRLKMHENANH 1472
            ++I          LTQ  +E ++ + +++ EYE+  E L  E ++    +++   EN  +
Sbjct: 1425 AKIQNNLQ----NLTQEKEENDSKQDEIIKEYEQENETLRSENQNFETKIKVLEKENKLN 1480

Query: 1473 YETMQKESEIERVKLIEEL-NVK-ITESVSLNKQVAEL-NKALEEEVAKTNEMQTALENQ 1529
              ++QK ++ E+  L E+L N K + E++   K+  E  N  L+    K  ++ +  EN 
Sbjct: 1481 VFSLQKVTK-EKEDLAEKLKNQKEVNETLEKAKEDLETENNNLKLNEDKIKQILSENENL 1539

Query: 1530 EIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMN 1577
            + ++  L  E  +L N       K QK    +S   Q + E+L+N +N
Sbjct: 1540 KQKLNDLQKENNDLVNESNDIKQK-QKEEMESSKENQNQKEKLENDLN 1586



 Score =  147 bits (356), Expect = 3e-33
 Identities = 287/1442 (19%), Positives = 613/1442 (42%), Gaps = 135/1442 (9%)

Query: 155  DNALSVLQVKMKIMETTILDLQEKINEKDQIIEA---KNKATTXXXXXXXXXXXXXXXXX 211
            DN  S L+ ++K +   +    EKIN+   +++    +NK                    
Sbjct: 1140 DNENSQLENEIKKLTEDLQKQNEKINDNQNLLQNVTNENKKLKDKNELLFKENEQIKNLM 1199

Query: 212  EDTKQQMTKMQENFIAMEAEWKDEK---QRL---LKDIES--KDVRISSLEEANKLLEAA 263
            +D   +   ++E  I ME +   EK   +RL   LK+IE+  K  + ++ +E  KL +  
Sbjct: 1200 QDKINENNSLKEKQIEMENDLNTEKLNNERLVGRLKEIENHNKSKKDNTAKENAKLTQNN 1259

Query: 264  RFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTE 323
            +  ++ E+ +L Q++                ++ Q  E   E +    E   ++  N + 
Sbjct: 1260 K-ALANENFELKQKVANLDQELSDVKNKFDKMSSQISESEKEVQQNAAEFRQIKAKNES- 1317

Query: 324  LTKKIELLEHLNCQIRQTNKELENKLATMGTE-SKAVSSPSKKGSPLISRKS---GRNTA 379
            L K+++ L  L   ++Q N +L NK   + T  S+ + + S +   + ++       N  
Sbjct: 1318 LNKEVQFLNDLVTNLKQQNDDLRNKKEELNTTFSEDIDNISNELREIKTQNEFLRKENEE 1377

Query: 380  SKMKSPWSQLSSETLNQDTD--KKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXX 437
             K +S  ++  ++ L ++    K+IN   + K+   ++ LNK + D+   I         
Sbjct: 1378 MKNQSQLTKADNDKLKEENQNQKEINTKSLMKINE-LEKLNKQINDEMAKIQNNLQNLTQ 1436

Query: 438  XXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVN 497
                   K   I +   E++Q  E  +L     N E   ++ + + +L      ++    
Sbjct: 1437 EKEENDSKQDEIIK---EYEQ--ENETLRSENQNFETKIKVLEKENKLNVFSLQKVTKEK 1491

Query: 498  VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKL---KLKQMQKTIDNFS-KVSDS 553
             +DL EKLK+ +E    +N+ ++ A +++    +N KL   K+KQ+    +N   K++D 
Sbjct: 1492 -EDLAEKLKNQKE----VNETLEKAKEDLETENNNLKLNEDKIKQILSENENLKQKLNDL 1546

Query: 554  NKEIVRLTEELHHLSQKVAE-LEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETR 612
             KE   L  E + + QK  E +E  K N        +    +E+D+       +N  E +
Sbjct: 1547 QKENNDLVNESNDIKQKQKEEMESSKEN-------QNQKEKLENDLNDLQ---KNFDELQ 1596

Query: 613  LKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLE-----EQ 667
                 LLE  K +  Q+    + +++ V   L   S  Q+D +  ++K +  E     E+
Sbjct: 1597 KSYSDLLEKYKAENDQK----ESQFNNVNSNLKQ-SNYQNDLLQRKLKDLEEEMKNDKEK 1651

Query: 668  IDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKM 727
            ID L    +EL  +  N+K++          L  + E + ++  +  Q N ++T K +++
Sbjct: 1652 IDTLQNRNEELENLFGNMKIENSSALANSDKLTKENEALKSENLSLKQTNNEITTKNKEL 1711

Query: 728  SAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAV 787
            S E   E + +   E Q+  +  F   + I+E+   ++ +  E +  K+    L +    
Sbjct: 1712 SIEL--EKIKQNLEENQNSYENVFKEKSDIKEK---LDQLIQETNDQKAANKNLLKEKET 1766

Query: 788  MEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHE 847
            +E+ +   +++ + L   +  K KA +++ ++E+        + +    ++ ++++++ +
Sbjct: 1767 LEETQKQNQKEIENLIQKVT-KLKAKNDF-LKEN--------ITESKSKLQGEIIKLKED 1816

Query: 848  NKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNL 907
               + +K+    EE Q  +  LS+++  +  L+   N  DL     TK    L+    NL
Sbjct: 1817 LATMTQKSN---EEKQAQENELSNLKIEHEHLI---NNFDLL----TKGNENLKQKIGNL 1866

Query: 908  KRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRD-KKVLNEKYEKNIEYVTQLEAQLQE 966
             +   E +  I Q   E   L+ + N  +++ I + +K + ++ + ++E  ++ +  L E
Sbjct: 1867 TQENMESKKEIAQILLEKTTLQNQ-NDSLQNEIENLEKTIEKQKQDSVEIKSKFDQMLSE 1925

Query: 967  YKNNIE-NLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEI 1025
             KN +E N   N E+L K+  E    ++QK+  +      + IN++ + N  +K+   E 
Sbjct: 1926 MKNKMEKNKAENDEKLQKVEEE--KSNLQKENEE----IREKINKLQEENDEMKENFNES 1979

Query: 1026 IALNQ---KINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDS-KQHNEEL 1081
              +N+   K +N +  Y+  VS   ++L     +L    + + + ++ L +S ++   E 
Sbjct: 1980 QIMNESFAKEDNEKSLYIEKVSKQNAELQNDLKQLTKENKNLAKQNENLKNSFEKLKSET 2039

Query: 1082 QILVREQDDQIKELKETKLTFEMNIPKTEGM-IISSTIEPMSDDANNVDXXXXXXXXXXX 1140
             IL +  DD   +  +    F+ N  K   + ++ S         N              
Sbjct: 2040 DILQKNFDDLQTKFNDL---FDDNEQKASELEVVKSENSKQFAKINEQKQQLDNLIKENS 2096

Query: 1141 XLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLK 1200
             LKV+ E     E+ V  E++  L TE ++   +II+ +  +  L   +       + L+
Sbjct: 2097 SLKVRNELIAKNEQKV-SEENENLRTENEKMKKEIIEYDEKSQILQNENKKLSLLNDNLQ 2155

Query: 1201 SKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQ 1260
              L+   TENDNL +  + L++  ++  ++     +E+++  + +  A   K    L+ +
Sbjct: 2156 KDLQNKITENDNLKNMNSNLKNDKTNLGNK-----SEIFENQIKEISASLNK----LKSE 2206

Query: 1261 LSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRN----LQEKYADV 1316
              + E + E L +  +    E  ++   +E+V S    ++++ E L N    L +K +D+
Sbjct: 2207 NESLEKEKESLTEENKKLKSENQSQSSELEKVKSENTSMKNEVEKLANEKSELNKKISDL 2266

Query: 1317 INQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINE---E 1373
              QI+ L  E  D                     +L   N++ K   E+S  ++N+   E
Sbjct: 2267 QEQIDKLTKEKND---------------LSKQNEELVKGNETEKAKNEKSSADLNDFMNE 2311

Query: 1374 NAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDE 1433
            N Q+   +                 + +V  +  +L  K  EI +   E  I   +  ++
Sbjct: 2312 NKQILADNNRMKEEIQNLKLSAEKCQNEVNRVLEELG-KVVEI-KSLSEIPILFIENKEK 2369

Query: 1434 FENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESE--IERVKLIEEL 1491
             E+  + L   +  I+  +    +E+ +    +  +++H+  +  + +  +  +  ++ L
Sbjct: 2370 MESTLKLLDNIKSLIKCESNTSNNEIPLKIQNILNDSDHFANIVAKIKKILPEITSVDSL 2429

Query: 1492 NVKITESVSLNKQVAELN-KALEEEVAKT-NEMQTALENQEIEIVTLNDEITNLQNMVRA 1549
             +K+        +  ELN KAL    A++ +E+   +   +       D  TN+Q+++ +
Sbjct: 2430 PIKVQIMKDKLTEFEELNDKALNVANARSIHELPNLISKLKQISSNFEDRETNIQSLLDS 2489

Query: 1550 SS 1551
             S
Sbjct: 2490 YS 2491



 Score =  122 bits (295), Expect = 6e-26
 Identities = 248/1188 (20%), Positives = 506/1188 (42%), Gaps = 124/1188 (10%)

Query: 476  NEIAKVQEQLKQELNDEIKDVNVKDL----IEKLKSAEEQ--ITQLNDEIDAANKNMIK- 528
            +EIA+++ QLKQ    +I ++  K L    I   K A+++  I  L  +I    KN I  
Sbjct: 82   DEIAELKSQLKQADASKITELGEKLLDATSIHAEKEAQQRGCIKMLKAQISELQKNSIPQ 141

Query: 529  -----VKSNHKLKLKQMQKTIDN--FSKVSDSNKEI--VRLT---------EELHHLSQK 570
                    +    LK   K +    FS VS    +I   R+          ++   + +K
Sbjct: 142  IAMSFSAGSGAKSLKDDCKILKQLIFSYVSQMQSDIHTARIVATALKRACDKKTRKVIRK 201

Query: 571  VAELEE-EKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRL-KAISLLESQKFDLVQ 628
            + EL E     LQ  +  ++S      D  K+M       E R  + I  L+ +   L  
Sbjct: 202  LRELAEIHIPELQTQITQHESTEQQLKDSMKEMRATSLEKEKRFQEEILKLKDEIRSLQD 261

Query: 629  ELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQI---DALSASKKELALVIENL 685
               +L+++   +E+ + DI     + + ++  ++ L +++   DA   +K    L + N 
Sbjct: 262  NNKMLEEQNKLLEESVKDIHTESQNILENDNDTIKLNQELAVKDAQLEAKDIEILKLRNA 321

Query: 686  KLDKEQLYGT-IKDLENDKEDIMNKLQNYI-------QENMDLTDKLEKMSAEKISELLA 737
               + Q + T     EN    +  +++           EN    +KL+K   +K+ +L  
Sbjct: 322  LYTENQKFTTAYSQTENRDSPLAEEIKTLTLTMSQLKDENTRNQEKLKKFKDDKL-KLKQ 380

Query: 738  KINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYS--L 795
             ++  E  +++ +     +I + +  I N++ EL   K  I   ++ I+ M +R  +  L
Sbjct: 381  ALHQNELDRVKDENKYKPQINDLNTKISNLQKELENAKDTIDAKQKKISTMYERMKAPLL 440

Query: 796  E--RKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIE-----HEN 848
            E  +K +QL S +        +       L +R++   D++  ++ ++ ++E     HEN
Sbjct: 441  EQNQKINQLESLIDTLNAKNGKQKDSIKLLKDRISQFQDNNSKLQAKIAKLEATAKIHEN 500

Query: 849  KE--LQKKNQILLEENQNLQISLSDMQQHYNALVE-KANRTDLAESESTKYQTQLRDLES 905
            ++  L  K   L +EN   + ++  +Q    +L E K   T      + K+Q ++ D   
Sbjct: 501  EKETLNSKIDYLSKENNIKEDTVKKVQDANQSLKEYKETATKQITDNTQKFQ-EILDENQ 559

Query: 906  NLKRITHEHQTLIVQKKKEIEDLEIEFN---TQIESAIRDKKVLNEKYEKNIEYVTQLEA 962
            + +    E    +++ +K+I+DL   FN    QI+    +   + +K ++ ++  ++L+ 
Sbjct: 560  SYREKNAELSRKLLESQKQIDDLINGFNDKDQQIKGIKGEAGTVKQKIKELLDENSKLKN 619

Query: 963  QLQEYKNNIEN-------LNMNVEELNKMN--LE--LIDKHVQKQQTQSPDYT-EQYINE 1010
            ++ E   +++N         +  +E  K N  L+  L DK+ +    +  + T E  IN+
Sbjct: 620  KISELDQSLKNSQTAQKQTTLKTQEQLKQNDSLQNILEDKNSELLSLKELNSTNENQINK 679

Query: 1011 I-NKLNALLKQKDEEIIALNQKI--NNAQVSYMSMVSDYESKLAQFTTKLEN-MEEEMQR 1066
            +  KL+ L K+ DE  ++L QK+   N ++   ++ SD  + L Q    L++ M++    
Sbjct: 680  LKTKLDNLQKENDELKVSL-QKVTERNDELENTTIKSDKANDLIQENMTLKSQMKDAKNE 738

Query: 1067 VSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDAN 1126
             +K + + KQ   E ++L + Q +  KE+KE       NI     + + + +  +  D N
Sbjct: 739  NAKTMNEMKQIQLENELLKQNQQNLEKEIKE-------NI--QNNLDLQNKLNKIEWD-N 788

Query: 1127 NVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELT 1186
             +             L   + E    +  +L E   K+  E      K+  L  LN    
Sbjct: 789  KIVSDKLAKEKSSLEL---QNENLQNQNKLLNENHQKVTEENLAISQKLNDLNNLNKMCQ 845

Query: 1187 GHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQR 1246
                     + + + +LE L  + +NL     ++++   S  +    +I +L K+   Q 
Sbjct: 846  DELQSTSLTLQRKEKELEDLKQKMENLEKEFYDVKTEKMSMEN----KIFDLEKESKNQN 901

Query: 1247 EADFQKTEHELRVQLSAFESKYEQLLD---SVQSSTQE-----ETNKIVTMEQVTSLQNK 1298
            + +  K   +  +Q+    +K E+L +   ++Q+  +E       N+IV  E  T L  K
Sbjct: 902  D-NMNKIIEDKDLQIKDLRTKNEKLTEENSNLQNKEKENKNLQSRNQIVEKEN-TELSQK 959

Query: 1299 LQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQS 1358
            +  + E +  L+   + + NQ  IL ++ + +KV                  DL   N S
Sbjct: 960  ISSQNERINELENAVSTLQNQ--ILENDDKSQKV------------TEQTAKDLIAANSS 1005

Query: 1359 YKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQ---LELKDSE 1415
             KQM  Q+ L   ++N +++                 +D + ++LEL ++   +     +
Sbjct: 1006 LKQMTYQNELLQRKQN-EMENDLDEKSSRIKDLEDENDDLQKEILELQNENRKISSNYEK 1064

Query: 1416 IYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYET 1475
            I ++ +   + + Q  DE E+ +Q+LV+  K+     +E+E    I   K  ++     T
Sbjct: 1065 ISKENNRIEMEMKQIKDENESNKQKLVDNTKK-----HEEEKMNLINNAKSDKSKIDGLT 1119

Query: 1476 MQKESEIERVKLIEELNVKI-TESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIV 1534
                     +KL+++ N K+  E+  L  ++ +L + L+++  K N+ Q  L+N   E  
Sbjct: 1120 KDISMLNSNIKLLQDENSKLDNENSQLENEIKKLTEDLQKQNEKINDNQNLLQNVTNENK 1179

Query: 1535 TLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLD 1582
             L D+   L        + +Q  ++  +  K+ +  +++N +N E L+
Sbjct: 1180 KLKDKNELLFKENEQIKNLMQDKINENNSLKE-KQIEMENDLNTEKLN 1226



 Score =  118 bits (284), Expect = 1e-24
 Identities = 221/1131 (19%), Positives = 504/1131 (44%), Gaps = 98/1131 (8%)

Query: 237  QRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLA---QELEQXXXXXXXXXXXXX 293
            Q++ K+ E    ++ + +E N+ LE A+ ++  E++ L     +++Q             
Sbjct: 1485 QKVTKEKEDLAEKLKNQKEVNETLEKAKEDLETENNNLKLNEDKIKQILSENENLKQKLN 1544

Query: 294  XLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMG 353
             L K++ +    E  +I++K   E+ +  E   + E LE+    +++   EL+   + + 
Sbjct: 1545 DLQKENND-LVNESNDIKQKQKEEMESSKENQNQKEKLENDLNDLQKNFDELQKSYSDLL 1603

Query: 354  TESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMV 413
             + KA +   +      S+ +  N+  K  +  + L    L +D ++++ KN+  K++  
Sbjct: 1604 EKYKAENDQKE------SQFNNVNSNLKQSNYQNDLLQRKL-KDLEEEM-KNDKEKID-T 1654

Query: 414  IQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTE 473
            +Q+ N++L +    +  +++           ++  +    L  +Q         + T  +
Sbjct: 1655 LQNRNEELENLFGNMKIENSSALANSDKLTKENEALKSENLSLKQTNN-----EITTKNK 1709

Query: 474  DVN-EIAKVQEQLKQELNDEIKDVNVK-DLIEKLKSAEEQITQLNDEIDAANKNMIKVKS 531
            +++ E+ K+++ L++  N        K D+ EKL   ++ I + ND+  AANKN++K K 
Sbjct: 1710 ELSIELEKIKQNLEENQNSYENVFKEKSDIKEKL---DQLIQETNDQ-KAANKNLLKEKE 1765

Query: 532  NHKLKLKQMQKTIDNF----SKVSDSNKEIVR-LTEELHHLSQKVAELEEEKGNLQLHLV 586
              +   KQ QK I+N     +K+   N  +   +TE    L  ++ +L+E+   +     
Sbjct: 1766 TLEETQKQNQKEIENLIQKVTKLKAKNDFLKENITESKSKLQGEIIKLKEDLATMTQKSN 1825

Query: 587  DYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLAD 646
            +    +  E+++    IE E+L    +    LL     +L Q++  L Q  + +E K  +
Sbjct: 1826 EEKQAQ--ENELSNLKIEHEHL----INNFDLLTKGNENLKQKIGNLTQ--ENMESK-KE 1876

Query: 647  ISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKD-LENDKED 705
            I+Q+  ++   + ++  L+ +I+ L  + ++       +K   +Q+   +K+ +E +K +
Sbjct: 1877 IAQILLEKTTLQNQNDSLQNEIENLEKTIEKQKQDSVEIKSKFDQMLSEMKNKMEKNKAE 1936

Query: 706  IMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDA---KIQERDL 762
               KLQ   +E  +L  + E++  EKI++L  + +  +++  ++Q   ++   +  E+ L
Sbjct: 1937 NDEKLQKVEEEKSNLQKENEEIR-EKINKLQEENDEMKENFNESQIMNESFAKEDNEKSL 1995

Query: 763  YIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDE 822
            YIE +  + ++ ++ + +L +    +  +  +L+   ++L S     QK + +   + ++
Sbjct: 1996 YIEKVSKQNAELQNDLKQLTKENKNLAKQNENLKNSFEKLKSETDILQKNFDDLQTKFND 2055

Query: 823  LVNRLAVLMDHDRVVE----KQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNA 878
            L +          VV+    KQ  +I  + ++L      L++EN +L++  +++      
Sbjct: 2056 LFDDNEQKASELEVVKSENSKQFAKINEQKQQLDN----LIKENSSLKVR-NELIAKNEQ 2110

Query: 879  LVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLI---VQKKKEIEDLEIEFNTQ 935
             V + N     E+E  K +    D +S + +  ++  +L+   +QK  + +  E +    
Sbjct: 2111 KVSEENENLRTENEKMKKEIIEYDEKSQILQNENKKLSLLNDNLQKDLQNKITENDNLKN 2170

Query: 936  IESAIR-DKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKH-- 992
            + S ++ DK  L  K E     + ++ A L + K+  E+L    E L + N +L  ++  
Sbjct: 2171 MNSNLKNDKTNLGNKSEIFENQIKEISASLNKLKSENESLEKEKESLTEENKKLKSENQS 2230

Query: 993  -------VQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSD 1045
                   V+ + T   +  E+  NE ++LN  +    E+I  L ++ N+       +V  
Sbjct: 2231 QSSELEKVKSENTSMKNEVEKLANEKSELNKKISDLQEQIDKLTKEKNDLSKQNEELVKG 2290

Query: 1046 YESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQIL----------VREQDDQIKEL 1095
             E++ A+      ++ + M    + L D+ +  EE+Q L          V    +++ ++
Sbjct: 2291 NETEKAKNEKSSADLNDFMNENKQILADNNRMKEEIQNLKLSAEKCQNEVNRVLEELGKV 2350

Query: 1096 KETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQ----EEEEF- 1150
             E K   E+ I   E      +   + D+  ++             LK+Q    + + F 
Sbjct: 2351 VEIKSLSEIPILFIENKEKMESTLKLLDNIKSLIKCESNTSNNEIPLKIQNILNDSDHFA 2410

Query: 1151 ---IQERSVLQEQSA--KLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQ 1205
                + + +L E ++   L  ++Q    K+ + E LN +    +V N   I++L + + +
Sbjct: 2411 NIVAKIKKILPEITSVDSLPIKVQIMKDKLTEFEELNDKAL--NVANARSIHELPNLISK 2468

Query: 1206 LNTENDNLLSTVAELRSSISS-AVDQRGFEIAELWKQHLAQRE-----ADFQKTEHELR- 1258
            L   + N       ++S + S + D+   E++ L K++  Q+      +    +E+ L  
Sbjct: 2469 LKQISSNFEDRETNIQSLLDSYSFDELPAELSRLLKENTDQKALLRSISSIINSENILER 2528

Query: 1259 -VQLSAFESKYEQLLDSVQS-STQEETNKIVTMEQVTSLQNKLQDKEEHLR 1307
              +L   E   E+L     + S+ ++  KI  +  +  L+NK+ +KE  ++
Sbjct: 2529 CSELIEIEQSMERLKKMCSAISSVDDDRKIEGI--LIDLKNKIDEKERTIQ 2577



 Score = 96.3 bits (229), Expect = 6e-18
 Identities = 250/1249 (20%), Positives = 533/1249 (42%), Gaps = 138/1249 (11%)

Query: 149  NTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXX 208
            +T++ ++  L  L   MKI  ++ L   +K+ ++++ ++++N +                
Sbjct: 1653 DTLQNRNEELENLFGNMKIENSSALANSDKLTKENEALKSENLSLKQTNNEITTKNKELS 1712

Query: 209  XXXEDTKQQMTKMQ---ENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARF 265
               E  KQ + + Q   EN    +++ K++  +L+++   +     +L +  + LE  + 
Sbjct: 1713 IELEKIKQNLEENQNSYENVFKEKSDIKEKLDQLIQETNDQKAANKNLLKEKETLEETQK 1772

Query: 266  EISLEHSKLAQEL---------------EQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEI 310
            +   E   L Q++               E               LA  + + + E++ + 
Sbjct: 1773 QNQKEIENLIQKVTKLKAKNDFLKENITESKSKLQGEIIKLKEDLATMTQKSNEEKQAQE 1832

Query: 311  EEKGSLEIA------NMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSK 364
             E  +L+I       N   LTK  E L+     + Q N E + ++A +  E   + + + 
Sbjct: 1833 NELSNLKIEHEHLINNFDLLTKGNENLKQKIGNLTQENMESKKEIAQILLEKTTLQNQND 1892

Query: 365  KGSPLISR-----KSGRNTASKMKSPWSQLSSETLNQ-DTDKKINKNEIAKLEMV---IQ 415
                 I       +  +  + ++KS + Q+ SE  N+ + +K  N  ++ K+E     +Q
Sbjct: 1893 SLQNEIENLEKTIEKQKQDSVEIKSKFDQMLSEMKNKMEKNKAENDEKLQKVEEEKSNLQ 1952

Query: 416  SLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDV 475
              N+++ +K   + E++             +   A+   E   ++E  S      N E  
Sbjct: 1953 KENEEIREKINKLQEENDEMKENFNESQIMNESFAKEDNEKSLYIEKVSK----QNAELQ 2008

Query: 476  NEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLN-DEIDAANKNMIKVKSNHK 534
            N++ ++ ++ K   N   ++ N+K+  EKLKS E  I Q N D++     ++        
Sbjct: 2009 NDLKQLTKENK---NLAKQNENLKNSFEKLKS-ETDILQKNFDDLQTKFNDLFDDNEQKA 2064

Query: 535  LKLKQMQ-KTIDNFSKVSDSNKEIVRLTEELHHL---SQKVAELE----EEKGNLQLHLV 586
             +L+ ++ +    F+K+++  +++  L +E   L   ++ +A+ E    EE  NL+    
Sbjct: 2065 SELEVVKSENSKQFAKINEQKQQLDNLIKENSSLKVRNELIAKNEQKVSEENENLRTENE 2124

Query: 587  DYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLAD 646
                  +IE D   ++++ EN      K +SLL     D +Q+   LQ K  E  D L +
Sbjct: 2125 KMKK-EIIEYDEKSQILQNEN------KKLSLLN----DNLQK--DLQNKITE-NDNLKN 2170

Query: 647  I-SQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKED 705
            + S L++D+     KS   E QI  +SAS  +L    E+L+ +KE L    K L+++ + 
Sbjct: 2171 MNSNLKNDKTNLGNKSEIFENQIKEISASLNKLKSENESLEKEKESLTEENKKLKSENQS 2230

Query: 706  IMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIE 765
              ++L+    EN  + +++EK++ EK SEL  KI     S +Q Q  ID   +E+     
Sbjct: 2231 QSSELEKVKSENTSMKNEVEKLANEK-SELNKKI-----SDLQEQ--IDKLTKEK----- 2277

Query: 766  NIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVN 825
               ++LSK        EE +   E  +   E+ +  L  ++ E ++  ++    ++E+ N
Sbjct: 2278 ---NDLSKQN------EELVKGNETEKAKNEKSSADLNDFMNENKQILADNNRMKEEIQN 2328

Query: 826  RLAVLMDHDRVVEKQLLEIEH--ENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKA 883
                       V + L E+    E K L +   + +E  + ++ +L  +  +  +L++  
Sbjct: 2329 LKLSAEKCQNEVNRVLEELGKVVEIKSLSEIPILFIENKEKMESTLK-LLDNIKSLIKCE 2387

Query: 884  NRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIR-- 941
            + T   E    K Q  L D +     +    +  I+ +   ++ L I+     +      
Sbjct: 2388 SNTSNNEI-PLKIQNILNDSDHFANIVAKIKK--ILPEITSVDSLPIKVQIMKDKLTEFE 2444

Query: 942  --DKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEEL------NKMNLELIDKHV 993
              + K LN    ++I  +  L ++L++  +N E+   N++ L      +++  EL    +
Sbjct: 2445 ELNDKALNVANARSIHELPNLISKLKQISSNFEDRETNIQSLLDSYSFDELPAEL--SRL 2502

Query: 994  QKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQ--VSYMSMVSDYESKLA 1051
             K+ T          + IN  N L  ++  E+I + Q +   +   S +S V D + K+ 
Sbjct: 2503 LKENTDQKALLRSISSIINSENIL--ERCSELIEIEQSMERLKKMCSAISSVDD-DRKIE 2559

Query: 1052 QFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQD--DQIKELKETKLTFEMNIPKT 1109
                 L+N  +E +R       + Q +E L     E D   ++ ++K   + +E  I + 
Sbjct: 2560 GILIDLKNKIDEKER-------TIQTSEALIPPSFEGDLPKKVLQMKNKIIEYEQKISQF 2612

Query: 1110 EGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTE-L 1168
               I     +P+S     ++            +++ + +  I   ++    S   + + +
Sbjct: 2613 VNAIGGG--DPISSSRKILESFNNSNSLLTEVIRILKSDPNI---TLTYPFSPSFSAQII 2667

Query: 1169 QECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAEL--RSSISS 1226
            ++C+  I +LE  N+  + + V+N+ + N      + L      L++ + E+  R SI  
Sbjct: 2668 EDCHNLIRKLE--NSVKSINTVLNECKGNGYSG--DDLQEAVHYLVNHLVEIERRKSIEK 2723

Query: 1227 AVDQRGFEIAELWKQHLAQREADFQKTEHEL---RVQLSAFESKYEQLLDSVQSSTQEET 1283
             V++ G E+ ++  Q ++    + +KT  ++   R Q+ A E +++   D+  +  +   
Sbjct: 2724 HVNEIG-ELRKIHSQEVSILTQNKEKTMEQVKKCREQIIALEKQFQAKEDNYINDLENLK 2782

Query: 1284 NKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKV 1332
             +  ++      Q ++  K+E +  +  K AD I  + +  S+IE + +
Sbjct: 2783 TEQYSLSDKLRKQQRI--KDELITFVSGKPAD-IEFLSVNLSDIEKKSI 2828


>UniRef50_Q23QC3 Cluster: Viral A-type inclusion protein repeat
            containing protein; n=1; Tetrahymena thermophila
            SB210|Rep: Viral A-type inclusion protein repeat
            containing protein - Tetrahymena thermophila SB210
          Length = 2948

 Score =  175 bits (425), Expect = 1e-41
 Identities = 301/1485 (20%), Positives = 650/1485 (43%), Gaps = 155/1485 (10%)

Query: 220  KMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELE 279
            K++EN   ++ E  D KQ+L +     +  +S++    +  ++ + E+++ + K+ ++ +
Sbjct: 1024 KLRENIEQLQQEVDDLKQQLEQAGRENEETVSAITLFKQNSDSQKQELNILNQKIEEQQK 1083

Query: 280  QXXXXXXXXXXXXXX--LAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQ 337
            Q                +A+++++   EE          +   M E +++ E++E L   
Sbjct: 1084 QIQSLLSQKSDLQHLKEVAEENLQLKTEEFDRFRMNLDTDQQVMLEGSEQKEIIESLKKH 1143

Query: 338  IRQTNKELENKLATMGTESKAV--------SSPSKKGSPLISRKSGRNTASKMKSPWSQL 389
            I +   +L +K   +  + + +         S S+K   +   +    +   MK   ++L
Sbjct: 1144 IEELESQLSDKDFILLQKQQEIIQMNAEKYESSSEKDKLVNKIEELEESVISMKKQ-NKL 1202

Query: 390  SSETLN-----QDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXG 444
              + LN     QD  ++  K++I +  + I++L + + D +  I EKD            
Sbjct: 1203 QEQELNECKRLQDEQQEELKSQIKQNNIQIENLKQLIQDMQRQIDEKDDQLEQSQKDKVQ 1262

Query: 445  KDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVN--------EIAKVQEQLKQELNDEIKDV 496
             +  I QL   +  +++    +     ++           E   +++Q  +EL + +K+V
Sbjct: 1263 NELEIQQLSESNNDYIKEIQALSKQIYSQQAQIHQQKVELEDFDIRKQQFEEL-EHLKEV 1321

Query: 497  NVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKS-----NHKLKLKQMQKTIDNFSKVS 551
             + +L   ++  E+Q+  L ++ +   +    ++S     N K + ++ +K      +  
Sbjct: 1322 KINELENLIEQYEKQLKNLQEKEEKIEEVCSSLESSVSPINQKSQKQEKEKCEGKQVEEE 1381

Query: 552  DSNKEI-VRLTEELHHLSQKVAELEEEKGNLQLHLVDYDS-GRMIES---DVYKKM---- 602
            DS  ++ +++ E    + Q+ +E+ E+K  +QL   +  +    +ES   D+ KK     
Sbjct: 1382 DSKLQLEIQIEEFQEKIQQQESEITEDKQKIQLLEEEVKALQEKLESQQQDLEKKQQEFD 1441

Query: 603  IEMENLAETRLKAISL-LESQKFDLV---QELHILQQKYDEVEDKLADISQ-LQSDQVCS 657
            +E++ L ++  K  S   ES K  LV   QE+   +QK  E+E ++  + + L + Q   
Sbjct: 1442 LEIQELKKSNQKDDSEEKESLKEQLVEQNQEIVEYKQKLSELEQEVQSLQEKLDTQQKEL 1501

Query: 658  EIKSVHLEEQIDALSASKK-----ELALVIENLKLDKEQLYGTIKDLENDKEDIMNK--- 709
            E + +   ++I+ L  + K     E+ ++ + L   K  L   +++LE    +  N    
Sbjct: 1502 ERRQIEFNQEIEQLKKANKNEEESEVEVLNQQLTEQKTSLENQVEELEQKLSECQNSITS 1561

Query: 710  LQNYIQENMDLTDKLE--KMSAEKISELLAKIN---HEEQSKIQTQFG-----IDAKIQE 759
            LQ  IQ+  +   KL   K+  E+ ++   K+    +EE +K+Q+++          ++E
Sbjct: 1562 LQQQIQKQEEEISKLNENKLILEQDNQEFQKMTQQFNEEHTKLQSEYQNILSFYKQAVEE 1621

Query: 760  RDLYIENIESELSKYKSRICR-LEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTI 818
            RD    NI+ +  ++++   + LE+ I+  ++ R + +++  +    LQ+K++  +E   
Sbjct: 1622 RD----NIKQQQQEFETITQKALEDKIS--KENRQNQQQREYEYAQLLQQKEELIAELGK 1675

Query: 819  QEDELVNRLAVLMDHD-------RVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSD 871
              + L ++L  +           R ++ +  E E   K+L  K +  ++EN  LQ+ L+D
Sbjct: 1676 NANNLKDKLTQIEQLSIEQQIAIRSLDTEKKEQEKSIKKLNDKLEFQIQENDQLQL-LTD 1734

Query: 872  MQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKK---EIEDL 928
              Q    L +  N+ ++ E++   ++   ++ E  LK + +E++ L  ++ +   ++E+L
Sbjct: 1735 RYQ--KELSKIRNQNEVNENQIKNFKLLKQEQEDQLKELQNENKQLKQRESELQIKVEEL 1792

Query: 929  EIEF-NTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLE 987
            E    N QI    RD++  +   ++  E    L  Q+ E  N I+     ++E  + N E
Sbjct: 1793 ESSLKNIQISQKFRDEQKTSVNNDRQQE---DLNNQINELNNQIDLFKQQIKEQQE-NAE 1848

Query: 988  LIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYE 1047
                 VQ+ Q Q     E    EI +L   L+  + +I     K  + +     +  D +
Sbjct: 1849 EQSLRVQQSQEQQLKQKE----EIEELKTKLETFENQIENYKTKEEDLKTQIDDLQQDKD 1904

Query: 1048 SKLAQFTTKLENMEEEMQRVSK--QLLDSKQHNEELQILV---REQDDQIKELKETKLTF 1102
              L + T K + ++E +Q+  K  +L D      E Q+L     E+++ +++ +   L F
Sbjct: 1905 MLLRKKTEKDQRIDELIQQNDKISELCDKLNLQIEQQLLTIRENEENESLQQEQVDNLKF 1964

Query: 1103 EMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQER------SV 1156
            ++   KT+   I      ++  A N               K+++E E ++E+      + 
Sbjct: 1965 QIEELKTQNDKIQVQSGELA--AQNEAFSIKIQLLENQIAKLKDENELLKEKQPERTHAY 2022

Query: 1157 LQEQSAKLNT-ELQ-ECYTKII--QLETLNTELTGHDVVNQEQIN-----------QLKS 1201
             ++ S++ NT EL+ E    ++  Q+   N ++   +   Q++IN           Q +S
Sbjct: 2023 SKQSSSEPNTPELEREDNENVLEQQINLPNEKIENQEKEKQQKINFEQKIEADNTLQSQS 2082

Query: 1202 KLEQLNTENDNLLSTVAE---LRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELR 1258
              EQ N+   N +++  E   L  S+  A+++   + A L +  L Q+   +++ + + R
Sbjct: 2083 ISEQDNSSYQNGIASSPEKEDLIKSLQKALEELKSQ-ASLKENVLNQKLNHYKEKKRQYR 2141

Query: 1259 VQLSAFESKYEQLLDSVQSSTQ---------EETNKIVTMEQVTSLQNKLQDKEEHLRNL 1309
              L   E KY+++   +++ T+         EE  KIV  E    + N L  ++  L   
Sbjct: 2142 ESLKHSEQKYKEIQYRIETETRTLQTRIQVLEEEQKIVQNESQLQI-NDLSAQKVTLYQE 2200

Query: 1310 QEKYADVINQI--EILRSEI--EDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQ 1365
             +K  + INQ+  ++ R E+  ++ +                   D+ ++    + + E 
Sbjct: 2201 NQKQIEKINQLNEQLKRQELVLQETQRQLRNEQSSARNDSEAVDSDVESKINEIESLTED 2260

Query: 1366 SILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTI 1425
              L + EE  Q  +              ++   + K+LE  H     +SE+   + +   
Sbjct: 2261 KKL-LKEEIQQKDQLIYQYVEQISDLEKQLQKTQQKLLEGNHNSSPNESELQIMSMQRNE 2319

Query: 1426 TLTQRNDEF----ENVRQQLVEYEKRIEDLT-YEKESELAILRLKMHENANHYETMQKES 1480
            T +  N+E     E V Q +   +++I  L+ + +E E  +  L+   N    E  Q E 
Sbjct: 2320 TTSSTNEENIFKEEEVNQTIQMLKEQILILSEHAQEKENNLTALQDSINTYLSEKEQYEK 2379

Query: 1481 EIERVK-LIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDE 1539
            +I  +  L E+L  ++ E  +   Q+ ELN   E    KT +++  L  ++ +I+ L  E
Sbjct: 2380 QIANLNSLNEQLQQQVDELNNFKNQIGELNPQTE----KTEQLENQLSQKDEQILCLEQE 2435

Query: 1540 ITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAV 1584
            I  L+  ++ ++S      S + ++    +E+ DN  NK+L + +
Sbjct: 2436 INQLKEKIQTANS------SGSGESNSNENEE-DNQKNKDLNELI 2473



 Score =  173 bits (422), Expect = 3e-41
 Identities = 315/1464 (21%), Positives = 636/1464 (43%), Gaps = 152/1464 (10%)

Query: 212  EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLE- 270
            ++ ++++T++++    +  +  +++Q+ L  ++ +       +E  K+LE    +I  E 
Sbjct: 842  KELEEKITQLEDQVQVLNTQLAEQQQQHLDHLQQQSELRD--QEILKILEQKTIQIEAEL 899

Query: 271  HSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEE----KGSLEIANMTELTK 326
            ++  A +LEQ               A+QS     + +  +E+    K  +E       + 
Sbjct: 900  NATFANKLEQEVQSALQQSNNNKEQAEQSQFYQAQYRKVLEDYQQAKKIIESLQKQNQSS 959

Query: 327  KIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPW 386
            + E+ EHL  QI +  ++L+ + A  G+  K V    ++   LI +     T +      
Sbjct: 960  QKEV-EHLKNQIERITEDLDVQTANQGSTQKYV----QENQALIIKIKELETTN------ 1008

Query: 387  SQLSSETLN-QDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGK 445
            ++L+SE  N +  D K+ +N I +L+  +  L + L   E    E +             
Sbjct: 1009 NELTSEIFNFEKNDAKLREN-IEQLQQEVDDLKQQL---EQAGRENEETVSAITLFKQNS 1064

Query: 446  DTLIAQLQLEHQ----QHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIK---DVNV 498
            D+   +L + +Q    Q  +  SL+   ++ + + E+A+   QLK E  D  +   D + 
Sbjct: 1065 DSQKQELNILNQKIEEQQKQIQSLLSQKSDLQHLKEVAEENLQLKTEEFDRFRMNLDTDQ 1124

Query: 499  KDLIEKLKSAE--EQITQLNDEIDA--ANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSN 554
            + ++E  +  E  E + +  +E+++  ++K+ I ++   ++    +Q   + +   S+ +
Sbjct: 1125 QVMLEGSEQKEIIESLKKHIEELESQLSDKDFILLQKQQEI----IQMNAEKYESSSEKD 1180

Query: 555  KEIVRLTEELHHL---SQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAET 611
            K +V   EEL       +K  +L+E++ N    L D +    ++S + +  I++ENL + 
Sbjct: 1181 K-LVNKIEELEESVISMKKQNKLQEQELNECKRLQD-EQQEELKSQIKQNNIQIENLKQL 1238

Query: 612  RL--------KAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVH 663
                      K   L +SQK  +  EL I QQ  +   D + +I  L S Q+ S+   +H
Sbjct: 1239 IQDMQRQIDEKDDQLEQSQKDKVQNELEI-QQLSESNNDYIKEIQAL-SKQIYSQQAQIH 1296

Query: 664  LEE-QIDALSASKKELALV--IENLKLDK-----EQLYGTIKDLENDKEDIMNKLQNYIQ 715
             ++ +++     K++   +  ++ +K+++     EQ    +K+L+  +E I     +   
Sbjct: 1297 QQKVELEDFDIRKQQFEELEHLKEVKINELENLIEQYEKQLKNLQEKEEKIEEVCSSLES 1356

Query: 716  ENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYK 775
                +  K +K   EK      K   EE SK+Q +  I+ + QE+   I+  ESE+++ K
Sbjct: 1357 SVSPINQKSQKQEKEKCE---GKQVEEEDSKLQLEIQIE-EFQEK---IQQQESEITEDK 1409

Query: 776  SRICRLEESIAV----MEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLM 831
             +I  LEE +      +E ++  LE+K  +    +QE +K+  +   +E E +    V  
Sbjct: 1410 QKIQLLEEEVKALQEKLESQQQDLEKKQQEFDLEIQELKKSNQKDDSEEKESLKEQLVEQ 1469

Query: 832  DHDRVVEKQ-LLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAE 890
            + + V  KQ L E+E E + LQ+K     +E +  QI   +  Q    L +KAN+ +  E
Sbjct: 1470 NQEIVEYKQKLSELEQEVQSLQEKLDTQQKELERRQI---EFNQEIEQL-KKANKNE-EE 1524

Query: 891  SESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIE--SAIRDKKVLNE 948
            SE      QL + +++L+    E +  + + +  I  L+ +   Q E  S + + K++ E
Sbjct: 1525 SEVEVLNQQLTEQKTSLENQVEELEQKLSECQNSITSLQQQIQKQEEEISKLNENKLILE 1584

Query: 949  KYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQ---TQSPDYTE 1005
            +  +  + +TQ   Q  E    +++   N+    K  +E  D   Q+QQ   T +    E
Sbjct: 1585 QDNQEFQKMTQ---QFNEEHTKLQSEYQNILSFYKQAVEERDNIKQQQQEFETITQKALE 1641

Query: 1006 QYINEINKLN---------ALLKQKDEEIIALNQKINNA--QVSYMSMVS-DYESKLAQF 1053
              I++ N+ N          LL+QK+E I  L +  NN   +++ +  +S + +  +   
Sbjct: 1642 DKISKENRQNQQQREYEYAQLLQQKEELIAELGKNANNLKDKLTQIEQLSIEQQIAIRSL 1701

Query: 1054 TTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGM- 1112
             T+ +  E+ +++++ +L    Q N++LQ+L    D   KEL + +   E+N  + +   
Sbjct: 1702 DTEKKEQEKSIKKLNDKLEFQIQENDQLQLLT---DRYQKELSKIRNQNEVNENQIKNFK 1758

Query: 1113 IISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECY 1172
            ++    E    +  N +            +KV+E E  ++   +    S K   E +   
Sbjct: 1759 LLKQEQEDQLKELQN-ENKQLKQRESELQIKVEELESSLKNIQI----SQKFRDEQKTSV 1813

Query: 1173 TKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRG 1232
                Q E LN ++  +++ NQ  + + + K +Q N E  +L      ++ S    + Q+ 
Sbjct: 1814 NNDRQQEDLNNQI--NELNNQIDLFKQQIKEQQENAEEQSL-----RVQQSQEQQLKQKE 1866

Query: 1233 FEIAEL-WKQHLAQREADFQKT-EHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTME 1290
             EI EL  K    + + +  KT E +L+ Q+   +   + LL       Q     I   +
Sbjct: 1867 -EIEELKTKLETFENQIENYKTKEEDLKTQIDDLQQDKDMLLRKKTEKDQRIDELIQQND 1925

Query: 1291 QVTSLQNKLQDKEEH----LRNLQEKYADVINQIEILRSEIED-----EKVAFXXXXXXX 1341
            +++ L +KL  + E     +R  +E  +    Q++ L+ +IE+     +K+         
Sbjct: 1926 KISELCDKLNLQIEQQLLTIRENEENESLQQEQVDNLKFQIEELKTQNDKIQVQSGELAA 1985

Query: 1342 XXXXXXXXXDLRTENQSYKQMQEQSILNINE---ENAQLKKSSXXXXXXXXXXXXRVNDA 1398
                      L  ENQ  K   E  +L   +    +A  K+SS              N  
Sbjct: 1986 QNEAFSIKIQL-LENQIAKLKDENELLKEKQPERTHAYSKQSSSEPNTPELEREDNENVL 2044

Query: 1399 EAKVLELTHQLELKDSEIYQKTH-----EYTITL------TQRNDEFENVRQQLVEYE-- 1445
            E ++     ++E ++ E  QK +     E   TL       Q N  ++N      E E  
Sbjct: 2045 EQQINLPNEKIENQEKEKQQKINFEQKIEADNTLQSQSISEQDNSSYQNGIASSPEKEDL 2104

Query: 1446 -KRIEDLTYEKESELAILRLKMHENANHYETMQ---KESEIERVKLIEELNVKI-TESVS 1500
             K ++    E +S+ ++    +++  NHY+  +   +ES     +  +E+  +I TE+ +
Sbjct: 2105 IKSLQKALEELKSQASLKENVLNQKLNHYKEKKRQYRESLKHSEQKYKEIQYRIETETRT 2164

Query: 1501 LNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSF 1560
            L  ++  L    EE+    NE Q  + +   + VTL  E       +   + ++++    
Sbjct: 2165 LQTRIQVLE---EEQKIVQNESQLQINDLSAQKVTLYQENQKQIEKINQLNEQLKRQELV 2221

Query: 1561 ASDT-KQGRDEQLDNTMNKELLDA 1583
              +T +Q R+EQ     + E +D+
Sbjct: 2222 LQETQRQLRNEQSSARNDSEAVDS 2245



 Score =  164 bits (399), Expect = 2e-38
 Identities = 233/1152 (20%), Positives = 495/1152 (42%), Gaps = 89/1152 (7%)

Query: 473  EDVNEIAKVQEQLKQELNDEIKDV-NVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKS 531
            ++  + A   E+ +QE+    K++ NVK  +  LK+ +      N ++D  NK +  +KS
Sbjct: 613  QNSQQAANKIEKYQQEIELYQKELSNVKQELGNLKNQQTN----NSDLDFLNKQLTNLKS 668

Query: 532  NHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSG 591
                K KQ++  I+       SN+   +L E+L    Q    L+ E   L+  L     G
Sbjct: 669  IFLDKKKQLELEIE------QSNQTHKQLKEKLSQALQSNQSLQSENIMLKNQLSLQTRG 722

Query: 592  RMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQ 651
                +D Y K+++ +       + I   E +   L QE+H L+ KYD+   ++ ++ +  
Sbjct: 723  ---SNDKYNKLMKQDQ------QNIQSFEHENNLLKQEMHNLKSKYDQ---EIEELKEKY 770

Query: 652  SDQVCS-EIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKD--LENDKEDIMN 708
             D + S E KS  L++Q+ A S + K++       +     L    KD  +E  ++DI  
Sbjct: 771  QDYIFSIEEKSNELKKQL-ADSQNSKQMVKSASGTQNPLATLQLEAKDQIIEQQRQDIFG 829

Query: 709  KLQNYIQEN---MDLTDKLEKM--SAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLY 763
               NY  +N    +L +K+ ++    + ++  LA+   +    +Q Q  +  +   + L 
Sbjct: 830  LECNYRAQNDYIKELEEKITQLEDQVQVLNTQLAEQQQQHLDHLQQQSELRDQEILKILE 889

Query: 764  IENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDEL 823
             + I+ E     +   +LE+ +     +  + + +A+Q   Y  + +K   +Y  Q  ++
Sbjct: 890  QKTIQIEAELNATFANKLEQEVQSALQQSNNNKEQAEQSQFYQAQYRKVLEDYQ-QAKKI 948

Query: 824  VNRLAVL-MDHDRVVEKQLLEIEHENKEL------QKKNQILLEENQNLQISLSDMQQHY 876
            +  L        + VE    +IE   ++L      Q   Q  ++ENQ L I + +++   
Sbjct: 949  IESLQKQNQSSQKEVEHLKNQIERITEDLDVQTANQGSTQKYVQENQALIIKIKELETTN 1008

Query: 877  NALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQI 936
            N L  +       E    K +  +  L+  +  +  + +    + ++ +  + + F    
Sbjct: 1009 NELTSEIFN---FEKNDAKLRENIEQLQQEVDDLKQQLEQAGRENEETVSAITL-FKQNS 1064

Query: 937  ESAIRDKKVLNEKYE---KNIEYVTQLEAQLQEYKNNI-ENLNMNVEELNKMNLEL-IDK 991
            +S  ++  +LN+K E   K I+ +   ++ LQ  K    ENL +  EE ++  + L  D+
Sbjct: 1065 DSQKQELNILNQKIEEQQKQIQSLLSQKSDLQHLKEVAEENLQLKTEEFDRFRMNLDTDQ 1124

Query: 992  HVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLA 1051
             V  + ++  +  E     I +L + L  KD  ++   Q+I    +   +   +  S+  
Sbjct: 1125 QVMLEGSEQKEIIESLKKHIEELESQLSDKDFILLQKQQEI----IQMNAEKYESSSEKD 1180

Query: 1052 QFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEG 1111
            +   K+E +EE +  + KQ   +K   +EL    R QD+Q +ELK       + I   + 
Sbjct: 1181 KLVNKIEELEESVISMKKQ---NKLQEQELNECKRLQDEQQEELKSQIKQNNIQIENLKQ 1237

Query: 1112 MI--ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQ 1169
            +I  +   I+   D                  L  +   ++I+E   L +Q      ++ 
Sbjct: 1238 LIQDMQRQIDEKDDQLEQSQKDKVQNELEIQQLS-ESNNDYIKEIQALSKQIYSQQAQIH 1296

Query: 1170 ECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLL---STVAELRSSISS 1226
            +   ++   +    +    + + + +IN+L++ +EQ   +  NL      + E+ SS+ S
Sbjct: 1297 QQKVELEDFDIRKQQFEELEHLKEVKINELENLIEQYEKQLKNLQEKEEKIEEVCSSLES 1356

Query: 1227 AVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKI 1286
            +V     +  +  K+    ++ + + ++ +L +Q+  F+ K +Q     +S   E+  KI
Sbjct: 1357 SVSPINQKSQKQEKEKCEGKQVEEEDSKLQLEIQIEEFQEKIQQ----QESEITEDKQKI 1412

Query: 1287 VTM-EQVTSLQNKLQDKEEHLRNLQEKYADVINQI-EILRSEIEDEKVAFXXXXXXXXXX 1344
              + E+V +LQ KL+ +++ L   Q+++   I ++ +  + +  +EK +           
Sbjct: 1413 QLLEEEVKALQEKLESQQQDLEKKQQEFDLEIQELKKSNQKDDSEEKESLKEQLVEQNQE 1472

Query: 1345 XXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLE 1404
                   L    Q  + +QE+  L+  ++  + ++              + N+ E++V  
Sbjct: 1473 IVEYKQKLSELEQEVQSLQEK--LDTQQKELERRQIEFNQEIEQLKKANK-NEEESEVEV 1529

Query: 1405 LTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEK---ESELAI 1461
            L  QL  + + +  +  E    L++  +   +++QQ+ + E+ I  L   K   E +   
Sbjct: 1530 LNQQLTEQKTSLENQVEELEQKLSECQNSITSLQQQIQKQEEEISKLNENKLILEQDNQE 1589

Query: 1462 LRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAE--LNKALEEEVAKT 1519
             + KM +  N   T + +SE + +    +  V+  +++   +Q  E    KALE++++K 
Sbjct: 1590 FQ-KMTQQFNEEHT-KLQSEYQNILSFYKQAVEERDNIKQQQQEFETITQKALEDKISKE 1647

Query: 1520 N---------EMQTALENQEIEIVTLNDEITNLQN-MVRASSSKIQKHVSFAS-DTKQGR 1568
            N         E    L+ +E  I  L     NL++ + +     I++ ++  S DT++  
Sbjct: 1648 NRQNQQQREYEYAQLLQQKEELIAELGKNANNLKDKLTQIEQLSIEQQIAIRSLDTEKKE 1707

Query: 1569 DEQLDNTMNKEL 1580
             E+    +N +L
Sbjct: 1708 QEKSIKKLNDKL 1719



 Score =  159 bits (387), Expect = 4e-37
 Identities = 302/1526 (19%), Positives = 650/1526 (42%), Gaps = 139/1526 (9%)

Query: 99   KQK-EILMEKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEK--D 155
            KQK ++L E++K  +E  +     + +                  D +    ++KE+  +
Sbjct: 1409 KQKIQLLEEEVKALQEKLESQQQDLEKKQQEFDLEIQELKKSNQKDDSEEKESLKEQLVE 1468

Query: 156  NALSVLQVKMKI--METTILDLQEKINEKDQIIEAKN-KATTXXXXXXXXXXXXXXXXXE 212
                +++ K K+  +E  +  LQEK++ + + +E +  +                    E
Sbjct: 1469 QNQEIVEYKQKLSELEQEVQSLQEKLDTQQKELERRQIEFNQEIEQLKKANKNEEESEVE 1528

Query: 213  DTKQQMTKMQ---ENFIA-ME---AEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARF 265
               QQ+T+ +   EN +  +E   +E ++    L + I+ ++  IS L E   +LE    
Sbjct: 1529 VLNQQLTEQKTSLENQVEELEQKLSECQNSITSLQQQIQKQEEEISKLNENKLILE---- 1584

Query: 266  EISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELT 325
            + + E  K+ Q+  +                KQ++E     K + +E    E      L 
Sbjct: 1585 QDNQEFQKMTQQFNEEHTKLQSEYQNILSFYKQAVEERDNIKQQQQE---FETITQKALE 1641

Query: 326  KKIELLEHLNCQIR-----QTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTAS 380
             KI      N Q R     Q  ++ E  +A +G  +  +     +   L   +     + 
Sbjct: 1642 DKISKENRQNQQQREYEYAQLLQQKEELIAELGKNANNLKDKLTQIEQLSIEQQIAIRSL 1701

Query: 381  KMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXX 440
              +    + S + LN   + +I +N+  +L+++     K+L          +        
Sbjct: 1702 DTEKKEQEKSIKKLNDKLEFQIQEND--QLQLLTDRYQKELSKIRNQNEVNENQIKNFKL 1759

Query: 441  XXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIK-----D 495
                ++  + +LQ E++Q  +  S + +    E++    K   Q+ Q+  DE K     D
Sbjct: 1760 LKQEQEDQLKELQNENKQLKQRESELQI--KVEELESSLK-NIQISQKFRDEQKTSVNND 1816

Query: 496  VNVKDLIEKLKSAEEQIT----QLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVS 551
               +DL  ++     QI     Q+ ++ + A +  ++V+ + + +LKQ ++  +  +K+ 
Sbjct: 1817 RQQEDLNNQINELNNQIDLFKQQIKEQQENAEEQSLRVQQSQEQQLKQKEEIEELKTKLE 1876

Query: 552  DSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDS--GRMIE-SDVYKKMIEMENL 608
                +I     +   L  ++ +L+++K  L     + D     +I+ +D   ++ +  NL
Sbjct: 1877 TFENQIENYKTKEEDLKTQIDDLQQDKDMLLRKKTEKDQRIDELIQQNDKISELCDKLNL 1936

Query: 609  AETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLA-DISQLQSDQVCSEIKSVHLEEQ 667
             +   + +++ E+++ + +Q+  +   K+   E K   D  Q+QS ++ ++ ++  ++ Q
Sbjct: 1937 -QIEQQLLTIRENEENESLQQEQVDNLKFQIEELKTQNDKIQVQSGELAAQNEAFSIKIQ 1995

Query: 668  I--DALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNK-LQNYIQENMDL-TDK 723
            +  + ++  K E  L+ E  + ++   Y      E +  ++  +  +N +++ ++L  +K
Sbjct: 1996 LLENQIAKLKDENELLKEK-QPERTHAYSKQSSSEPNTPELEREDNENVLEQQINLPNEK 2054

Query: 724  LEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEE 783
            +E    EK  ++  +   E  + +Q+Q       Q+   Y   I S   K +  I  L++
Sbjct: 2055 IENQEKEKQQKINFEQKIEADNTLQSQ---SISEQDNSSYQNGIASSPEK-EDLIKSLQK 2110

Query: 784  SIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHD-RVVEKQLL 842
            ++  ++ +    E   +Q  ++ +EK++ Y E     ++    +   ++ + R ++ ++ 
Sbjct: 2111 ALEELKSQASLKENVLNQKLNHYKEKKRQYRESLKHSEQKYKEIQYRIETETRTLQTRIQ 2170

Query: 843  EIEHENKELQKKNQILLEENQNLQISLSDMQQHY----NALVEKANRTDLAESESTKYQT 898
             +E E K +Q ++Q+ + +    +++L    Q      N L E+  R +L   E+   Q 
Sbjct: 2171 VLEEEQKIVQNESQLQINDLSAQKVTLYQENQKQIEKINQLNEQLKRQELVLQET---QR 2227

Query: 899  QLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVT 958
            QLR+ +S+ +  +    + +  K  EIE L  E    ++  I+ K  L  +Y   +E ++
Sbjct: 2228 QLRNEQSSARNDSEAVDSDVESKINEIESLT-EDKKLLKEEIQQKDQLIYQY---VEQIS 2283

Query: 959  QLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALL 1018
             LE QLQ+ +  +   N N    N+  L+++   +Q+ +T S    E    E  ++N  +
Sbjct: 2284 DLEKQLQKTQQKLLEGNHNSSP-NESELQIMS--MQRNETTSSTNEENIFKE-EEVNQTI 2339

Query: 1019 KQKDEEIIALNQ----KINNAQV------SYMSMVSDYESKLAQFTTKLENMEEEMQRVS 1068
            +   E+I+ L++    K NN         +Y+S    YE ++A   +  E +++++  ++
Sbjct: 2340 QMLKEQILILSEHAQEKENNLTALQDSINTYLSEKEQYEKQIANLNSLNEQLQQQVDELN 2399

Query: 1069 K------QLLDSKQHNEELQILVREQDDQIKELKE--TKLTFEMNIPKTEGMIISSTIEP 1120
                   +L    +  E+L+  + ++D+QI  L++   +L  ++    + G   S++ E 
Sbjct: 2400 NFKNQIGELNPQTEKTEQLENQLSQKDEQILCLEQEINQLKEKIQTANSSGSGESNSNEN 2459

Query: 1121 MSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERS-VLQEQSAKLNTELQECYTKIIQLE 1179
              D+  N D             ++QE+  F +ER+  L E+      ++ +   +  +  
Sbjct: 2460 EEDNQKNKDLNELIESQKEKIQELQEQCTFNEERANQLMEECRAYGVKMADREEEFNKQM 2519

Query: 1180 TLNTELTGHDVVNQ-EQINQLKSKLEQLNTENDNLLSTVAELR----SSISSAVDQRGFE 1234
              N E     ++ + E+ + L S+ + LN E+ NL   + +L+    SS S+  DQ   E
Sbjct: 2520 ERNDEYYKKLLMRKNEEYSDLYSQYDSLNEESYNLKEEIEKLKNQKNSSSSNNSDQELAE 2579

Query: 1235 IAELWKQHLAQRE-ADFQKTE---------HELRVQLSAFESKYEQLLDSVQSSTQEETN 1284
            I    K+ + Q+E AD +K E          EL+ QL     +Y+ L   + S  Q+  +
Sbjct: 2580 IQTKLKEMVVQKEKADQEKEELEKSHNEAIQELKNQLENMRKEYDLLKSLLNSQAQQLIS 2639

Query: 1285 KIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXX 1344
            +    + VT       +K+E    L+E      N  E ++S IE E   F          
Sbjct: 2640 QAYN-QAVT-------EKDEDQSGLKET-----NNSENVKS-IESED--FQPIKQSQSPE 2683

Query: 1345 XXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLE 1404
                       NQ +   +  S L I  E++ L +              ++++ E + L+
Sbjct: 2684 ITPNKQFKAFSNQIHDD-ENSSELGIKVESSDLHEQIQDLKRQIVEKNIKISNLEGENLD 2742

Query: 1405 LTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRL 1464
            L  Q+    + +Y ++ EY   + ++  E      QL EY ++ +++     S     +L
Sbjct: 2743 LEDQV----NSLYAQSQEYRDKINKQYQE----NYQL-EYTQKCQNIKKSYRS-----KL 2788

Query: 1465 KMHENANHYETMQKESEIERVKLIEELNV--KITESVSLNKQV--AELNKALEEEVAKTN 1520
            K  E     E ++ +S+IER + IE   V  K+ +++ L  +    ++ +  EEE+ K N
Sbjct: 2789 KQIEENKKQEMIELKSQIERERNIEMKMVKEKLEKNIQLLDEAYKMQIQQVREEELCKYN 2848

Query: 1521 E-MQTALENQEIEIVTLNDEITNLQN 1545
            + +Q   +  E +I  L   +   QN
Sbjct: 2849 QILQEMKQEYEQKIQELKTTLNESQN 2874



 Score =  154 bits (374), Expect = 2e-35
 Identities = 257/1303 (19%), Positives = 558/1303 (42%), Gaps = 106/1303 (8%)

Query: 324  LTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPS---KKGSPLISRKSGRNTAS 380
            L KK +L   +  Q  QT+K+L+ KL+     ++++ S +   K    L +R S      
Sbjct: 671  LDKKKQLELEIE-QSNQTHKQLKEKLSQALQSNQSLQSENIMLKNQLSLQTRGSNDKYNK 729

Query: 381  KMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXX 440
             MK     + S     +  K+   N  +K +  I+ L +   D  + I EK         
Sbjct: 730  LMKQDQQNIQSFEHENNLLKQEMHNLKSKYDQEIEELKEKYQDYIFSIEEKSNELKKQLA 789

Query: 441  XXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKD 500
                 D+  ++  ++     + P L  +    +D     ++ EQ +Q++     + N + 
Sbjct: 790  -----DSQNSKQMVKSASGTQNP-LATLQLEAKD-----QIIEQQRQDIFG--LECNYRA 836

Query: 501  LIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRL 560
              + +K  EE+ITQL D++   N  + + +  H   L+Q  +  D         +EI+++
Sbjct: 837  QNDYIKELEEKITQLEDQVQVLNTQLAEQQQQHLDHLQQQSELRD---------QEILKI 887

Query: 561  TEELHHLSQKVAELEEEKGNLQLHLVDYD-SGRMIESDVYKKMIEMENLAETRLKAISLL 619
                  L QK  ++E E      + ++ +    + +S+  K+  E     + + + +   
Sbjct: 888  ------LEQKTIQIEAELNATFANKLEQEVQSALQQSNNNKEQAEQSQFYQAQYRKVLED 941

Query: 620  ESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELA 679
              Q   +++ L    QK ++   K  +  + Q +++  ++  V    Q       ++  A
Sbjct: 942  YQQAKKIIESL----QKQNQSSQKEVEHLKNQIERITEDL-DVQTANQGSTQKYVQENQA 996

Query: 680  LV--IENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLA 737
            L+  I+ L+    +L   I + E +   +   ++   QE  DL  +LE+   E    + A
Sbjct: 997  LIIKIKELETTNNELTSEIFNFEKNDAKLRENIEQLQQEVDDLKQQLEQAGRENEETVSA 1056

Query: 738  KINHEEQSKIQTQ--FGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDR--RY 793
                ++ S  Q Q    ++ KI+E+   I+++ S+ S  +      EE++ +  +   R+
Sbjct: 1057 ITLFKQNSDSQKQELNILNQKIEEQQKQIQSLLSQKSDLQHLKEVAEENLQLKTEEFDRF 1116

Query: 794  SLERKADQLGSYLQEKQKAYSEYTIQE-DELVNRLAVLMDHDRVV---EKQLLEIEHENK 849
             +    DQ       +QK   E   +  +EL ++L+   D D ++   +++++++  E  
Sbjct: 1117 RMNLDTDQQVMLEGSEQKEIIESLKKHIEELESQLS---DKDFILLQKQQEIIQMNAEKY 1173

Query: 850  ELQKKNQILLEENQNLQISLSDMQQHYNALVEKAN---RTDLAESESTKYQTQLRDLE-S 905
            E   +   L+ + + L+ S+  M++      ++ N   R    + E  K Q +  +++  
Sbjct: 1174 ESSSEKDKLVNKIEELEESVISMKKQNKLQEQELNECKRLQDEQQEELKSQIKQNNIQIE 1233

Query: 906  NLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQ----LE 961
            NLK++  + Q  I +K  ++E  + +   Q E  I+     N  Y K I+ +++     +
Sbjct: 1234 NLKQLIQDMQRQIDEKDDQLEQSQKD-KVQNELEIQQLSESNNDYIKEIQALSKQIYSQQ 1292

Query: 962  AQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYIN---EINKLNALL 1018
            AQ+ + K  +E+ ++  ++  ++   L +  + + +     Y +Q  N   +  K+  + 
Sbjct: 1293 AQIHQQKVELEDFDIRKQQFEELE-HLKEVKINELENLIEQYEKQLKNLQEKEEKIEEVC 1351

Query: 1019 KQKDEEIIALNQKINNAQVSYM--SMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQ 1076
               +  +  +NQK    +        V + +SKL Q   ++E  +E++Q+   ++ + KQ
Sbjct: 1352 SSLESSVSPINQKSQKQEKEKCEGKQVEEEDSKL-QLEIQIEEFQEKIQQQESEITEDKQ 1410

Query: 1077 H----NEELQILVREQDDQIKELKETKLTFEMNIPK-TEGMIISSTIEPMSDDANNVDXX 1131
                  EE++ L  + + Q ++L++ +  F++ I +  +      + E  S     V+  
Sbjct: 1411 KIQLLEEEVKALQEKLESQQQDLEKKQQEFDLEIQELKKSNQKDDSEEKESLKEQLVEQN 1470

Query: 1132 XXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLE--TLNTELTGHD 1189
                       ++++E + +QE+  L  Q  +L     E   +I QL+    N E +  +
Sbjct: 1471 QEIVEYKQKLSELEQEVQSLQEK--LDTQQKELERRQIEFNQEIEQLKKANKNEEESEVE 1528

Query: 1190 VVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAEL--WKQHLAQRE 1247
            V+NQ Q+ + K+ LE    E +  LS      +S+   + ++  EI++L   K  L Q  
Sbjct: 1529 VLNQ-QLTEQKTSLENQVEELEQKLSECQNSITSLQQQIQKQEEEISKLNENKLILEQDN 1587

Query: 1248 ADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETN-KIVTMEQVTSLQNKLQDK--EE 1304
             +FQK   +   + +  +S+Y+ +L   + + +E  N K    E  T  Q  L+DK  +E
Sbjct: 1588 QEFQKMTQQFNEEHTKLQSEYQNILSFYKQAVEERDNIKQQQQEFETITQKALEDKISKE 1647

Query: 1305 HLRNLQEK---YADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQ 1361
            + +N Q++   YA ++ Q E L +E+                        +R+ +   K+
Sbjct: 1648 NRQNQQQREYEYAQLLQQKEELIAELGKNANNLKDKLTQIEQLSIEQQIAIRSLDTEKKE 1707

Query: 1362 MQEQSILNINEE-NAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKT 1420
             QE+SI  +N++   Q++++               +  + ++ ++ +Q E+ +++I    
Sbjct: 1708 -QEKSIKKLNDKLEFQIQENDQLQLL--------TDRYQKELSKIRNQNEVNENQI---- 1754

Query: 1421 HEYTITLTQRND---EFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQ 1477
              + +   ++ D   E +N  +QL + E  ++    E ES L  +++          ++ 
Sbjct: 1755 KNFKLLKQEQEDQLKELQNENKQLKQRESELQIKVEELESSLKNIQISQKFRDEQKTSVN 1814

Query: 1478 KESEIERV-KLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTL 1536
             + + E +   I ELN +I       +Q+ E  +  EE+  +  + Q     Q+ EI  L
Sbjct: 1815 NDRQQEDLNNQINELNNQID---LFKQQIKEQQENAEEQSLRVQQSQEQQLKQKEEIEEL 1871

Query: 1537 NDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKE 1579
              ++   +N +    +K +   +   D +Q +D  L     K+
Sbjct: 1872 KTKLETFENQIENYKTKEEDLKTQIDDLQQDKDMLLRKKTEKD 1914



 Score =  110 bits (264), Expect = 4e-22
 Identities = 262/1419 (18%), Positives = 585/1419 (41%), Gaps = 143/1419 (10%)

Query: 93   SLANTLKQKEILMEKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIK 152
            SL   ++++E  + K+ + K + ++ +    +                   ++     ++
Sbjct: 1561 SLQQQIQKQEEEISKLNENKLILEQDNQEFQKMTQQFNEEHTKLQSEYQNILSFYKQAVE 1620

Query: 153  EKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXE 212
            E+DN     Q    I +  + D   K N ++Q  + +                       
Sbjct: 1621 ERDNIKQQQQEFETITQKALEDKISKENRQNQ--QQREYEYAQLLQQKEELIAELGKNAN 1678

Query: 213  DTKQQMTKMQENFIAMEAEWKD---EKQRLLKDIESKDVRISSLEEANKLLEAARFEISL 269
            + K ++T++++  I  +   +    EK+   K I+  + ++    + N  L+        
Sbjct: 1679 NLKDKLTQIEQLSIEQQIAIRSLDTEKKEQEKSIKKLNDKLEFQIQENDQLQLLTDRYQK 1738

Query: 270  EHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIE 329
            E SK+  + E               L KQ  E   ++  E++ +        +EL  K+E
Sbjct: 1739 ELSKIRNQNE-----VNENQIKNFKLLKQEQE---DQLKELQNENKQLKQRESELQIKVE 1790

Query: 330  LLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQL 389
             LE     I Q +++  ++  T     +     + + + L ++        K +   ++ 
Sbjct: 1791 ELESSLKNI-QISQKFRDEQKTSVNNDRQQEDLNNQINELNNQIDLFKQQIKEQQENAEE 1849

Query: 390  SSETLNQDTDKKIN-KNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTL 448
             S  + Q  ++++  K EI +L+  +++    +  + Y   E+D            KD L
Sbjct: 1850 QSLRVQQSQEQQLKQKEEIEELKTKLETFENQI--ENYKTKEEDLKTQIDDLQQD-KDML 1906

Query: 449  IAQLQLEHQQHMEGPSLIHVGTNTEDVNEIA-KVQEQLKQEL-----NDEIKDVNVKDLI 502
            + + + E  Q ++   LI      + ++E+  K+  Q++Q+L     N+E + +  ++ +
Sbjct: 1907 LRK-KTEKDQRID--ELIQ---QNDKISELCDKLNLQIEQQLLTIRENEENESLQ-QEQV 1959

Query: 503  EKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTE 562
            + LK   E++   ND+I   +  +        +K++ ++  I   +K+ D N+ +     
Sbjct: 1960 DNLKFQIEELKTQNDKIQVQSGELAAQNEAFSIKIQLLENQI---AKLKDENELLKEKQP 2016

Query: 563  ELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQ 622
            E  H   K +  E     L+      D+  ++E  +     ++EN  + + + I+  +  
Sbjct: 2017 ERTHAYSKQSSSEPNTPELERE----DNENVLEQQINLPNEKIENQEKEKQQKINFEQKI 2072

Query: 623  KFD-LVQELHILQQKYDEVEDKLADISQLQS-----DQVCSEIKS-VHLEEQI--DALSA 673
            + D  +Q   I +Q     ++ +A   + +       +   E+KS   L+E +    L+ 
Sbjct: 2073 EADNTLQSQSISEQDNSSYQNGIASSPEKEDLIKSLQKALEELKSQASLKENVLNQKLNH 2132

Query: 674  SKKELALVIENLKLDKEQLYGTIK-DLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKI 732
             K++     E+LK   EQ Y  I+  +E +   +  ++Q  ++E   +     ++    +
Sbjct: 2133 YKEKKRQYRESLK-HSEQKYKEIQYRIETETRTLQTRIQ-VLEEEQKIVQNESQLQINDL 2190

Query: 733  SELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRR 792
            S     +  E Q +I+    ++ +++ ++L ++  + +L   +S      +S AV  D  
Sbjct: 2191 SAQKVTLYQENQKQIEKINQLNEQLKRQELVLQETQRQLRNEQSSA--RNDSEAVDSD-- 2246

Query: 793  YSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQ 852
              +E K +++ S L E +K   E   Q+D+L+ +            +Q+ ++E   K+LQ
Sbjct: 2247 --VESKINEIES-LTEDKKLLKEEIQQKDQLIYQYV----------EQISDLE---KQLQ 2290

Query: 853  KKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITH 912
            K  Q LLE N N   + S++Q     +  + N T    + ST  +   ++ E N      
Sbjct: 2291 KTQQKLLEGNHNSSPNESELQ----IMSMQRNET----TSSTNEENIFKEEEVNQTIQML 2342

Query: 913  EHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIE 972
            + Q LI+ +  + ++  +   T ++ +I       E+YEK I  +  L  QLQ+  + + 
Sbjct: 2343 KEQILILSEHAQEKENNL---TALQDSINTYLSEKEQYEKQIANLNSLNEQLQQQVDELN 2399

Query: 973  NLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKI 1032
            N    + ELN              QT+    TEQ  N++++ +  +   ++EI  L +KI
Sbjct: 2400 NFKNQIGELN-------------PQTEK---TEQLENQLSQKDEQILCLEQEINQLKEKI 2443

Query: 1033 NNAQVSYMSMVSDYES-----KLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVRE 1087
              A  S     +  E+     K       +E+ +E++Q + +Q   +++   +L    R 
Sbjct: 2444 QTANSSGSGESNSNENEEDNQKNKDLNELIESQKEKIQELQEQCTFNEERANQLMEECRA 2503

Query: 1088 QDDQIKELKET-KLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQE 1146
               ++ + +E      E N    + +++    E  SD  +  D            ++  +
Sbjct: 2504 YGVKMADREEEFNKQMERNDEYYKKLLMRKN-EEYSDLYSQYDSLNEESYNLKEEIEKLK 2562

Query: 1147 EEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQL 1206
             ++     +   ++ A++ T+L+E    ++Q E  + E    +  + E I +LK++LE +
Sbjct: 2563 NQKNSSSSNNSDQELAEIQTKLKE---MVVQKEKADQEKEELEKSHNEAIQELKNQLENM 2619

Query: 1207 NTENDNLLSTV-AELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFE 1265
              E D L S + ++ +  IS A +Q   E  E         ++  ++T +   V+  + E
Sbjct: 2620 RKEYDLLKSLLNSQAQQLISQAYNQAVTEKDE--------DQSGLKETNNSENVK--SIE 2669

Query: 1266 SKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLR-NLQEKYADVINQIEILR 1324
            S      +  Q   Q ++ +I   +Q  +  N++ D E      ++ + +D+  QI+ L+
Sbjct: 2670 S------EDFQPIKQSQSPEITPNKQFKAFSNQIHDDENSSELGIKVESSDLHEQIQDLK 2723

Query: 1325 SEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSY-----KQMQEQSILNINEENAQLKK 1379
             +I ++ +                   L  ++Q Y     KQ QE   L   ++   +KK
Sbjct: 2724 RQIVEKNIKI-SNLEGENLDLEDQVNSLYAQSQEYRDKINKQYQENYQLEYTQKCQNIKK 2782

Query: 1380 SSXXXXXXXXXXXXRVNDAEAKVLELTHQLELK---DSEIYQKTHEYTITLTQR--NDEF 1434
            S                + + +++EL  Q+E +   + ++ ++  E  I L       + 
Sbjct: 2783 SYRSKLKQIE------ENKKQEMIELKSQIERERNIEMKMVKEKLEKNIQLLDEAYKMQI 2836

Query: 1435 ENVR-QQLVEYEKRIEDLTYEKESELAILRLKMHENANH 1472
            + VR ++L +Y + ++++  E E ++  L+  ++E+ N+
Sbjct: 2837 QQVREEELCKYNQILQEMKQEYEQKIQELKTTLNESQNN 2875



 Score =  110 bits (264), Expect = 4e-22
 Identities = 217/1174 (18%), Positives = 485/1174 (41%), Gaps = 96/1174 (8%)

Query: 99   KQKEILMEKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDV--THLSNTIKEKD- 155
            +Q++ L E   + K+L +R S   ++               +  D   T ++N  +++D 
Sbjct: 1763 EQEDQLKELQNENKQLKQRESELQIKVEELESSLKNIQISQKFRDEQKTSVNNDRQQEDL 1822

Query: 156  -NALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDT 214
             N ++ L  ++ + +  I + QE   E+   ++   +                       
Sbjct: 1823 NNQINELNNQIDLFKQQIKEQQENAEEQSLRVQQSQEQQLKQKEEIEELKTKLETFENQI 1882

Query: 215  KQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKL 274
            +   TK +E+      + + +K  LL+    KD RI  L + N  +     +++L+  + 
Sbjct: 1883 ENYKTK-EEDLKTQIDDLQQDKDMLLRKKTEKDQRIDELIQQNDKISELCDKLNLQIEQQ 1941

Query: 275  AQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHL 334
               + +              L K  IE    +  +I+ +     A     + KI+LLE+ 
Sbjct: 1942 LLTIRENEENESLQQEQVDNL-KFQIEELKTQNDKIQVQSGELAAQNEAFSIKIQLLENQ 2000

Query: 335  NCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETL 394
              +++  N+ L+ K     T + +  S S+  +P + R+   N   +  +  ++   E  
Sbjct: 2001 IAKLKDENELLKEKQPER-THAYSKQSSSEPNTPELEREDNENVLEQQINLPNE-KIENQ 2058

Query: 395  NQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXG-KDTLIAQLQ 453
             ++  +KIN  +  + +  +QS +         ISE+D             K+ LI  LQ
Sbjct: 2059 EKEKQQKINFEQKIEADNTLQSQS---------ISEQDNSSYQNGIASSPEKEDLIKSLQ 2109

Query: 454  LEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQEL-NDEIKDVNVKDLIE-KLKSAEEQ 511
             +  + ++  + +      + +N   + + Q ++ L + E K   ++  IE + ++ + +
Sbjct: 2110 -KALEELKSQASLKENVLNQKLNHYKEKKRQYRESLKHSEQKYKEIQYRIETETRTLQTR 2168

Query: 512  ITQLNDEIDAA-NKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQK 570
            I  L +E     N++ +++      K+   Q+      K++  N+++ R  +EL  L + 
Sbjct: 2169 IQVLEEEQKIVQNESQLQINDLSAQKVTLYQENQKQIEKINQLNEQLKR--QELV-LQET 2225

Query: 571  VAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETR--LKA-ISLLESQKFDLV 627
              +L  E+ + +      +    ++SDV  K+ E+E+L E +  LK  I   +   +  V
Sbjct: 2226 QRQLRNEQSSAR------NDSEAVDSDVESKINEIESLTEDKKLLKEEIQQKDQLIYQYV 2279

Query: 628  QELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELAL---VIEN 684
            +++  L+++  + + KL + +   S    SE++ + ++      S +++ +     V + 
Sbjct: 2280 EQISDLEKQLQKTQQKLLEGNHNSSPNE-SELQIMSMQRNETTSSTNEENIFKEEEVNQT 2338

Query: 685  LKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSA------EKISELLAK 738
            +++ KEQ+   + +   +KE+ +  LQ+ I   +   ++ EK  A      E++ + + +
Sbjct: 2339 IQMLKEQIL-ILSEHAQEKENNLTALQDSINTYLSEKEQYEKQIANLNSLNEQLQQQVDE 2397

Query: 739  INH------EEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRR 792
            +N+      E   + +    ++ ++ ++D  I  +E E+++ K +I     S +   +  
Sbjct: 2398 LNNFKNQIGELNPQTEKTEQLENQLSQKDEQILCLEQEINQLKEKIQTANSSGSGESNSN 2457

Query: 793  YSLE--RKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHE-NK 849
             + E  +K   L   ++ +++   E   Q      R   LM+  R    ++ + E E NK
Sbjct: 2458 ENEEDNQKNKDLNELIESQKEKIQELQEQCTFNEERANQLMEECRAYGVKMADREEEFNK 2517

Query: 850  ELQKKNQILLEENQNLQISLSDMQQHYNALVEKAN--RTDLAESESTKYQTQLRDLESNL 907
            ++++ ++   +         SD+   Y++L E++   + ++ + ++ K  +   + +  L
Sbjct: 2518 QMERNDEYYKKLLMRKNEEYSDLYSQYDSLNEESYNLKEEIEKLKNQKNSSSSNNSDQEL 2577

Query: 908  KRITHEHQTLIVQKKK---EIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQL 964
              I  + + ++VQK+K   E E+LE   N  I+      + + ++Y+     +     QL
Sbjct: 2578 AEIQTKLKEMVVQKEKADQEKEELEKSHNEAIQELKNQLENMRKEYDLLKSLLNSQAQQL 2637

Query: 965  --QEYKNNIENLNMNVEELNKMNLELIDKHVQKQ------QTQSPDYTEQYINEINKLNA 1016
              Q Y   +   + +   L + N     K ++ +      Q+QSP+ T    N+  K  +
Sbjct: 2638 ISQAYNQAVTEKDEDQSGLKETNNSENVKSIESEDFQPIKQSQSPEITP---NKQFKAFS 2694

Query: 1017 LLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEE----------MQR 1066
                 DE    L  K+ ++ +     + D + ++ +   K+ N+E E          +  
Sbjct: 2695 NQIHDDENSSELGIKVESSDLH--EQIQDLKRQIVEKNIKISNLEGENLDLEDQVNSLYA 2752

Query: 1067 VSKQLLD--SKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDD 1124
             S++  D  +KQ+ E  Q+   ++   IK+   +KL       K E + + S IE   + 
Sbjct: 2753 QSQEYRDKINKQYQENYQLEYTQKCQNIKKSYRSKLKQIEENKKQEMIELKSQIERERNI 2812

Query: 1125 ANNV--DXXXXXXXXXXXXLKVQ----EEEEFIQERSVLQEQSAKLNTELQECYTKIIQL 1178
               +  +             K+Q     EEE  +   +LQE   +   ++QE  T     
Sbjct: 2813 EMKMVKEKLEKNIQLLDEAYKMQIQQVREEELCKYNQILQEMKQEYEQKIQELKT----- 2867

Query: 1179 ETLNTELTGHDVVNQEQINQLKSKLEQLNTENDN 1212
             TLN     +   N    N +  + E  N  N+N
Sbjct: 2868 -TLNESQNNNIGNNVNAPNLISDQQEFGNNSNNN 2900



 Score =  105 bits (252), Expect = 1e-20
 Identities = 173/865 (20%), Positives = 369/865 (42%), Gaps = 84/865 (9%)

Query: 742  EEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQ 801
            +E S+I      + K+ + DL ++N +   +K +    + ++ I + +     L     +
Sbjct: 590  QENSQISAGKLNNDKMYQEDLLLQNSQQAANKIE----KYQQEIELYQKE---LSNVKQE 642

Query: 802  LGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEE 861
            LG+ L+ +Q   S+      +L N  ++ +D  + +E ++ +    +K+L++K    L+ 
Sbjct: 643  LGN-LKNQQTNNSDLDFLNKQLTNLKSIFLDKKKQLELEIEQSNQTHKQLKEKLSQALQS 701

Query: 862  NQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQK 921
            NQ+LQ S + M ++  +L  + +        + KY   ++  + N++   HE+  L    
Sbjct: 702  NQSLQ-SENIMLKNQLSLQTRGS--------NDKYNKLMKQDQQNIQSFEHENNLL---- 748

Query: 922  KKEIEDLEIEFNTQIESAIRDK--KVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVE 979
            K+E+ +L+ +++ +IE  +++K    +    EK+ E   QL A  Q  K  +++ +    
Sbjct: 749  KQEMHNLKSKYDQEIEE-LKEKYQDYIFSIEEKSNELKKQL-ADSQNSKQMVKSASGTQN 806

Query: 980  ELNKMNLELIDKHVQKQQTQ----SPDYTEQYINEINKLNALLKQKDEEIIALNQKINNA 1035
             L  + LE  D+ +++Q+        +Y  Q  + I +L   + Q ++++  LN ++   
Sbjct: 807  PLATLQLEAKDQIIEQQRQDIFGLECNYRAQN-DYIKELEEKITQLEDQVQVLNTQLAEQ 865

Query: 1036 QVSYM------SMVSDYE--SKLAQFTTKLE---------NMEEEMQRVSKQLLDSKQHN 1078
            Q  ++      S + D E    L Q T ++E          +E+E+Q   +Q  ++K+  
Sbjct: 866  QQQHLDHLQQQSELRDQEILKILEQKTIQIEAELNATFANKLEQEVQSALQQSNNNKEQA 925

Query: 1079 EELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXX 1138
            E+ Q    +    +++ ++ K   E ++ K +       +E + +    +          
Sbjct: 926  EQSQFYQAQYRKVLEDYQQAKKIIE-SLQK-QNQSSQKEVEHLKNQIERITEDLDVQTAN 983

Query: 1139 XXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQ 1198
                     ++++QE   L  +  +L T   E  ++I   E  + +L  +    Q++++ 
Sbjct: 984  QG-----STQKYVQENQALIIKIKELETTNNELTSEIFNFEKNDAKLRENIEQLQQEVDD 1038

Query: 1199 LKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGF---EIAELWK--QHLAQREADFQ-- 1251
            LK +LEQ   EN+  +S +   + +  S   +      +I E  K  Q L  +++D Q  
Sbjct: 1039 LKQQLEQAGRENEETVSAITLFKQNSDSQKQELNILNQKIEEQQKQIQSLLSQKSDLQHL 1098

Query: 1252 KTEHELRVQLSAFE-SKYEQLLDSVQSSTQE--ETNKIV--TMEQVTSLQNKLQDKEEHL 1306
            K   E  +QL   E  ++   LD+ Q    E  E  +I+    + +  L+++L DK+  L
Sbjct: 1099 KEVAEENLQLKTEEFDRFRMNLDTDQQVMLEGSEQKEIIESLKKHIEELESQLSDKDFIL 1158

Query: 1307 RNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQS 1366
              LQ++   +    E   S  E +K+                   ++ +N+  +Q   + 
Sbjct: 1159 --LQKQQEIIQMNAEKYESSSEKDKLV------NKIEELEESVISMKKQNKLQEQELNEC 1210

Query: 1367 ILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTIT 1426
                +E+  +LK                + D + ++ E   QLE    +  Q   E    
Sbjct: 1211 KRLQDEQQEELKSQIKQNNIQIENLKQLIQDMQRQIDEKDDQLEQSQKDKVQNELEIQQL 1270

Query: 1427 LTQRND---EFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIE 1483
                ND   E + + +Q+   + +I     E E     +R +  E   H + + K +E+E
Sbjct: 1271 SESNNDYIKEIQALSKQIYSQQAQIHQQKVELED--FDIRKQQFEELEHLKEV-KINELE 1327

Query: 1484 RVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNL 1543
               LIE+   ++       +++ E+  +LE  V+  N+     E ++ E   + +E + L
Sbjct: 1328 --NLIEQYEKQLKNLQEKEEKIEEVCSSLESSVSPINQKSQKQEKEKCEGKQVEEEDSKL 1385

Query: 1544 QNMVRAS--SSKIQKHVSFASDTKQ 1566
            Q  ++      KIQ+  S  ++ KQ
Sbjct: 1386 QLEIQIEEFQEKIQQQESEITEDKQ 1410



 Score = 66.1 bits (154), Expect = 8e-09
 Identities = 156/783 (19%), Positives = 310/783 (39%), Gaps = 68/783 (8%)

Query: 807  QEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQ 866
            Q++Q   S+ T  + +L    A L+    ++ + + + + +    Q++NQ L ++NQ   
Sbjct: 280  QQQQPQQSQQTKNQQQL-QHYAALVAQSNLMVQNMQQQQQQLLIKQEQNQHLQQQNQ--L 336

Query: 867  ISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIE 926
             S  ++  + N +  K  + + A         Q++  ++       + +      +K I 
Sbjct: 337  NSPQNVLSNNNTIGYKQVKQEQAYRYGRVLPNQMQVYDNAPLFPAQQQKAKETFYQKLIT 396

Query: 927  DLEIE-FNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMN 985
            D   + FN ++      ++ LN+         T +    Q  +N    L       +++ 
Sbjct: 397  DRNFQNFNQKLHVKKNQEQQLNQPQ-------TNIPVNSQSVRNKTIKLQFAQSLWHRIQ 449

Query: 986  LELIDKHVQKQQT-QSPDYTEQYINEINKLNALLKQ---------KDEEIIALN----QK 1031
               +  H   Q++ Q+   T Q++   NK   ++ Q         KD    ALN    Q 
Sbjct: 450  TRNLSAHQSPQESFQNIPKTLQFVTYNNKYQPIIPQSNIQANHQKKDSLDQALNHLLKQN 509

Query: 1032 INNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVS--KQLLDSKQHNEELQILVREQD 1089
            I N  +    +   ++ +L QF  + +  E+         Q+  S+ H      + +E D
Sbjct: 510  IPNNTIPLEQLEMRHKKQLDQFKQQAQRYEQSSSHKGGRLQMSFSESHTPRKNSISKESD 569

Query: 1090 D-QIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXL-KVQEE 1147
                +     K +FE      E   IS+  +  +D     D            + K Q+E
Sbjct: 570  GVGARSNSMQKKSFENFNSSQENSQISAG-KLNNDKMYQEDLLLQNSQQAANKIEKYQQE 628

Query: 1148 EEFIQ-ERSVLQEQSAKL------NTELQECYTKIIQLETLNTELTGHDVVNQEQIN--- 1197
             E  Q E S ++++   L      N++L     ++  L+++  +      +  EQ N   
Sbjct: 629  IELYQKELSNVKQELGNLKNQQTNNSDLDFLNKQLTNLKSIFLDKKKQLELEIEQSNQTH 688

Query: 1198 -QLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHE 1256
             QLK KL Q    N +L S    L++ +S  +  RG    + + + + Q + + Q  EHE
Sbjct: 689  KQLKEKLSQALQSNQSLQSENIMLKNQLS--LQTRGSN--DKYNKLMKQDQQNIQSFEHE 744

Query: 1257 ---LRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKY 1313
               L+ ++   +SKY+Q ++ ++   Q+    I   E+   L+ +L D  ++ + + +  
Sbjct: 745  NNLLKQEMHNLKSKYDQEIEELKEKYQDYIFSI--EEKSNELKKQLAD-SQNSKQMVKSA 801

Query: 1314 ADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXD-LRTENQSYKQMQEQ-SILNIN 1371
            +   N +  L+ E +D+ +                  D ++   +   Q+++Q  +LN  
Sbjct: 802  SGTQNPLATLQLEAKDQIIEQQRQDIFGLECNYRAQNDYIKELEEKITQLEDQVQVLNTQ 861

Query: 1372 EENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRN 1431
                Q +                +   E K +++  + EL  +   +   E    L Q N
Sbjct: 862  LAEQQQQHLDHLQQQSELRDQEILKILEQKTIQI--EAELNATFANKLEQEVQSALQQSN 919

Query: 1432 DEFENVRQQ---LVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLI 1488
            +  E   Q      +Y K +ED  Y++  ++ I  L+    ++  E    +++IER+   
Sbjct: 920  NNKEQAEQSQFYQAQYRKVLED--YQQAKKI-IESLQKQNQSSQKEVEHLKNQIERI--T 974

Query: 1489 EELNVKITESVSLNKQVAELNKAL----EEEVAKTNEMQTALENQEIEIVTLNDEITNLQ 1544
            E+L+V+     S  K V E N+AL    +E     NE+ + + N E     L + I  LQ
Sbjct: 975  EDLDVQTANQGSTQKYVQE-NQALIIKIKELETTNNELTSEIFNFEKNDAKLRENIEQLQ 1033

Query: 1545 NMV 1547
              V
Sbjct: 1034 QEV 1036


>UniRef50_A2EZE6 Cluster: Viral A-type inclusion protein, putative;
            n=1; Trichomonas vaginalis G3|Rep: Viral A-type inclusion
            protein, putative - Trichomonas vaginalis G3
          Length = 2098

 Score =  175 bits (425), Expect = 1e-41
 Identities = 314/1547 (20%), Positives = 652/1547 (42%), Gaps = 136/1547 (8%)

Query: 94   LANTLKQKEILMEKIKQ--YKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVT-HLSNT 150
            LA  +K+K+IL+  +++  YK  SK +  +  +               QL   T   ++ 
Sbjct: 47   LAQKIKEKDILIRSLQEENYKYRSKANQVSREQANEEKISQLGLKFQKQLNQKTLQYASQ 106

Query: 151  IKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXX 210
            +  +  ++S L+ ++K + T + + + K+    +  +AK +AT                 
Sbjct: 107  LSAQAKSISDLEAQVKKLNTELENTEVKLQTASKKQKAKLQATIKEKQAQIDTLNERIAQ 166

Query: 211  XEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLE 270
                 ++  K  E++       + + Q L ++I+SKDV I  LE  N + E    +I+  
Sbjct: 167  DSILYEESAKQLESY-------QQQIQSLNEEIKSKDVSI--LERDNTIRELEN-KINDI 216

Query: 271  HSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEI-ANMTELTKKIE 329
              K+ Q+ +Q              L K           E  +K S ++  ++ EL +K+ 
Sbjct: 217  VGKVDQKFKQSKDAIAEKEKIVAQLKKDPKNEGIVAAIEKADKSSSQLNESVNELQEKLS 276

Query: 330  LLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSG----RNTASKMKSP 385
              +    +   +  +L+  +    + S+       K + +   ++     ++   KM   
Sbjct: 277  KSQINGDESEVSASQLDISINKNDSASELCEIIQNKDNRIKELEAAVEELKHKPMKMNDI 336

Query: 386  WSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGK 445
             +Q S E   Q +  +I++ EI +L+   Q+L K++      ++EK             K
Sbjct: 337  -AQNSQENALQ-SQIEIHEQEIEELQATNQALEKEIEILNQRLAEKSDKTLNERISYLEK 394

Query: 446  DT--LIAQLQLEHQQHMEGPSLIH-----VGTNTEDVNEIAKVQE---QLKQEL---NDE 492
            +    +++ + +  Q  +  S I+     +    +   +I  +Q    +LK+ L   + E
Sbjct: 395  ELSKTLSENETQKTQINDFTSRINKYKAELDAKVDQEAQILTLQTLNTELKESLANKDKE 454

Query: 493  IKDVNV---KDLIEKLKSAEEQITQLNDEIDAANKNMIKVK---------SNHKLKLKQM 540
            I D+     KDL     S  ++ ++ N + D  N + + V           N  LK    
Sbjct: 455  IADLKALLDKDLSSNAGSPVKKASKTNTDEDEVNTSALDVTIDSPKQLKGENEDLKADNQ 514

Query: 541  QKTIDNFSKVSDSNK---EIVRLTEELHHLSQKVAELEE---EKGNLQLHLVDYDSG--R 592
            +   +N     DS+K   E  +LTEEL +L +++AEL+E   EKG+      + +S   +
Sbjct: 515  KLKQENDKLKQDSDKTSQENQKLTEELENLRKQLAELQEKSKEKGSDDSFSQELNSSLNQ 574

Query: 593  MIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQ--L 650
            + E+ +  K  E+E L     +   L E+Q    V++   LQ +  ++   L   S    
Sbjct: 575  VNEAIIQSKDEEIEELKGKLAELNGLFEAQ----VKQNEDLQAENTKLTQALEMFSNNDT 630

Query: 651  QSDQVCSEIKSVH-LEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNK 709
             S  V +     H L+E+I  L  +  +   + +NL+ D ++    I ++E + E    +
Sbjct: 631  SSSPVSAAKNFKHSLDEKIANLQDAVNKYREITDNLQNDNDEKAELIVNMEKEAEAFAER 690

Query: 710  LQNYIQENMDLTDKLEKMSAE--KIS-ELLAKINHEEQSK-----IQTQFGIDAKIQERD 761
            + +Y  E      ++E++ AE  K+  EL AK    EQ K     +Q +   + ++QE +
Sbjct: 691  INHYKSEIDSKDSEIERLKAEIDKLKGELAAKNTEAEQIKGQISDLQYKLSANGQMQEEN 750

Query: 762  ----LYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAY---- 813
                  I +++ EL    ++I  LE  +  + D+    +++ D L    +EK + +    
Sbjct: 751  NSLAKQIADLQKELENKANQIKDLESRLNSLNDQNELKQKEIDALKKQFREKSEQFDLLN 810

Query: 814  SEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKE-LQKKNQI--LLEENQNLQISLS 870
            SE      E   +   +  +  ++E++  EIE    E  QK  QI  L +EN+  +  + 
Sbjct: 811  SEINKLRSENEEKSKEINQNKALIEEKTKEIEALKAENAQKSQQINALSQENEQKKKQID 870

Query: 871  DM--------QQHYNALVE---KANRTDLAESESTKYQTQLRDL----ESNLKRITHEHQ 915
            ++        +Q  N  VE   K  + D    E+   + Q+ DL    E N K+I +  +
Sbjct: 871  NLSVENEQKKKQIDNLSVENEQKKKQIDNLSEENKLNKKQIDDLAEKNEQNEKQINNLSE 930

Query: 916  TLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLN 975
                QKKK+I++L  E N Q +  I D   L+E+ +   E + ++E+++++  N+ E   
Sbjct: 931  QN-EQKKKQIDNLSEE-NKQNKRQIDD---LSEENKLGKEKMNKIESEIRKVVNDTEMTP 985

Query: 976  MNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNA 1035
            + +      +     K   K   ++   ++       KL+ L K+KDE +I+  QK    
Sbjct: 986  VRLTSKFVADANEKKKDNAKLLEENKALSKAIDELQQKLDELHKEKDE-LISQAQKNQQE 1044

Query: 1036 QVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQ---- 1091
            +  +   +   +SKLA++   L+++++E +   +++      N+ ++ + R++ +Q    
Sbjct: 1045 KEEFGQFI---KSKLAEYADNLKSLDKERKEKDQEI---NALNDTIEAMRRQEIEQASHH 1098

Query: 1092 ---IKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEE 1148
               + +L  T  + E  I + +  + +   E +     N +             K +E E
Sbjct: 1099 YKDMSDLHNTNKSLEKQIEEMKEKVTNDD-EEVRLQLQNKEREITASKLMITN-KEKENE 1156

Query: 1149 EFIQERSVLQEQSAKLNTELQECYTKIIQLE---TLNT-ELTGHD---VVNQEQINQLKS 1201
            E  ++   L+E++ KL  E+QE   ++  L+   T+NT EL            +IN L  
Sbjct: 1157 ELKKQNEELKEKTEKLQKEVQEKEGEVNSLKLTFTMNTQELEKQKKEFAAKDTEINNLNQ 1216

Query: 1202 KLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQL 1261
            ++++LN E + + S + ++ S +    ++   +  +   Q  A++  D Q     ++ ++
Sbjct: 1217 EIQKLNQEAEKVTSELQKVTSDLQKVTEENAKKQEQEEDQSSAEKIQDLQSDIFNMKREI 1276

Query: 1262 SAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIE 1321
               +   E     +Q S ++ET+KI   E++  L++     ++  R L++++     + +
Sbjct: 1277 KTLKDDIENKEKEIQKS-KDETSKI--NEELNKLKSDKSKLDKENRTLKDQF----EKQK 1329

Query: 1322 ILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSS 1381
            IL S ++++                             +  ++Q+ ++I     + K + 
Sbjct: 1330 ILVSALQEQNNQSKFEEENKNLKTQLSAAKSEKSKLQQENTEKQNQIDILTAETERKSNQ 1389

Query: 1382 XXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQL 1441
                           D +   L      + +  +   K  E    L +   E E ++ QL
Sbjct: 1390 IRSHLTEIEQLKSKLDGQTNSLNDLKTYKQQSEQFNSKLDELQKNLAKAMKEKEEIQTQL 1449

Query: 1442 VEYEKRIEDLTYEKES---ELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITES 1498
             E  K  E++  + +    +   L+   ++  + YE ++ +S  + +   EEL  K+ + 
Sbjct: 1450 TESNKEKEEMQQKLDDGFRQFEELQDSYNQGMSKYEELE-QSYNQGMAQNEELKKKLNDE 1508

Query: 1499 VSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQN 1545
            +  NK   EL+K + E ++   E+ T L+  +  IV+L +E+   Q+
Sbjct: 1509 IKDNK---ELDKNMHELMSTNYEIDTQLKAAKQRIVSLEEEMKQFQS 1552



 Score =  171 bits (416), Expect = 1e-40
 Identities = 291/1352 (21%), Positives = 584/1352 (43%), Gaps = 137/1352 (10%)

Query: 307  KTEIEEKGSLEIANM-TELTKKIELLEHLNCQIRQTN---KELENKLATMGTESKAVSSP 362
            K+EI+ K S EI  +  E+ K    L   N +  Q      +L+ KL+  G   +  +S 
Sbjct: 695  KSEIDSKDS-EIERLKAEIDKLKGELAAKNTEAEQIKGQISDLQYKLSANGQMQEENNSL 753

Query: 363  SKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLV 422
            +K+ + L  +K   N A+++K   S+L+S  LN   + K  + +  K +   +S   DL+
Sbjct: 754  AKQIADL--QKELENKANQIKDLESRLNS--LNDQNELKQKEIDALKKQFREKSEQFDLL 809

Query: 423  DKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQ 482
            + E  I++  +              LI     E  + +E     +    ++ +N +++  
Sbjct: 810  NSE--INKLRSENEEKSKEINQNKALIE----EKTKEIEALKAENA-QKSQQINALSQEN 862

Query: 483  EQLKQELND-EIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQ 541
            EQ K+++++  +++   K  I+ L    EQ  +  D +   NK   K   +   K +Q +
Sbjct: 863  EQKKKQIDNLSVENEQKKKQIDNLSVENEQKKKQIDNLSEENKLNKKQIDDLAEKNEQNE 922

Query: 542  KTIDNFSKVSDSNK-EIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYK 600
            K I+N S+ ++  K +I  L+EE     +++ +L EE      + +  +    IES++ +
Sbjct: 923  KQINNLSEQNEQKKKQIDNLSEENKQNKRQIDDLSEE------NKLGKEKMNKIESEI-R 975

Query: 601  KMIEMENLAETRL--KAISLLESQKFD---LVQELHILQQKYDEVEDKLADISQLQSDQV 655
            K++    +   RL  K ++    +K D   L++E   L +  DE++ KL ++ + + + +
Sbjct: 976  KVVNDTEMTPVRLTSKFVADANEKKKDNAKLLEENKALSKAIDELQQKLDELHKEKDELI 1035

Query: 656  CSEIKSVHLEEQIDALSASKKELALVIENLK-LDKEQLYGTIKDLE-NDKEDIMNKLQNY 713
                K+   +E+      SK  LA   +NLK LDKE+     KD E N   D +  ++  
Sbjct: 1036 SQAQKNQQEKEEFGQFIKSK--LAEYADNLKSLDKERKE---KDQEINALNDTIEAMRR- 1089

Query: 714  IQENMDLTDKLEKMS-AEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELS 772
             QE    +   + MS     ++ L K   E + K+      D +++   L ++N E E++
Sbjct: 1090 -QEIEQASHHYKDMSDLHNTNKSLEKQIEEMKEKVTND---DEEVR---LQLQNKEREIT 1142

Query: 773  KYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSE----YTIQEDELVNRLA 828
              K  I   E+    ++ +   L+ K ++L   +QEK+   +     +T+   EL  +  
Sbjct: 1143 ASKLMITNKEKENEELKKQNEELKEKTEKLQKEVQEKEGEVNSLKLTFTMNTQELEKQKK 1202

Query: 829  VLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDL 888
                 D        EI + N+E+QK NQ   +    LQ   SD+Q+      E A + + 
Sbjct: 1203 EFAAKDT-------EINNLNQEIQKLNQEAEKVTSELQKVTSDLQK---VTEENAKKQEQ 1252

Query: 889  AESESTKYQTQLRDLESNLKRITHEHQTL---IVQKKKEIE---DLEIEFNTQIESAIRD 942
             E +S+  + Q  DL+S++  +  E +TL   I  K+KEI+   D   + N ++     D
Sbjct: 1253 EEDQSSAEKIQ--DLQSDIFNMKREIKTLKDDIENKEKEIQKSKDETSKINEELNKLKSD 1310

Query: 943  K-------KVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVE----ELNKMNLELIDK 991
            K       + L +++EK    V+ L+ Q  + K   EN N+  +    +  K  L+  + 
Sbjct: 1311 KSKLDKENRTLKDQFEKQKILVSALQEQNNQSKFEEENKNLKTQLSAAKSEKSKLQQENT 1370

Query: 992  HVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLA 1051
              Q Q       TE+  N+I      ++Q   ++      +N+ + +Y      + SKL 
Sbjct: 1371 EKQNQIDILTAETERKSNQIRSHLTEIEQLKSKLDGQTNSLNDLK-TYKQQSEQFNSKLD 1429

Query: 1052 QFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTE- 1110
            +    L    +E + +  QL +S +  EE+Q   ++ DD  ++ +E + ++   + K E 
Sbjct: 1430 ELQKNLAKAMKEKEEIQTQLTESNKEKEEMQ---QKLDDGFRQFEELQDSYNQGMSKYEE 1486

Query: 1111 -------GMIISSTIEPMSDDA--------NNVDXXXXXXXXXXXXLKVQEEEEFIQERS 1155
                   GM  +  ++   +D          N+             LK  ++     E  
Sbjct: 1487 LEQSYNQGMAQNEELKKKLNDEIKDNKELDKNMHELMSTNYEIDTQLKAAKQRIVSLEEE 1546

Query: 1156 VLQEQSAKLNTELQECYTKIIQLETLNTELTGH--DVVNQ------------EQINQLKS 1201
            + Q QS   +++L++  +K+I+L   N  +     D++ +            ++ N +KS
Sbjct: 1547 MKQFQSNDHSSDLEQLKSKLIELTKENNSIKSRNEDLIEENKSVKSKVDELSKENNSIKS 1606

Query: 1202 KLEQLNTENDNLLSTVAEL---RSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHE-- 1256
            K+ +LN EN    S + EL     S+ S + +R  EI E+ K  LA++  + ++TE++  
Sbjct: 1607 KVNELNNENSKSKSRIDELIKANDSLKSQLQERANEI-EIIKSELAEKSKE-KETENDEI 1664

Query: 1257 --LRVQLSAFESKYEQL---LDSVQSSTQEETNKIVTMEQVTSLQNK-LQDKEEHLRNLQ 1310
              L+ +L   + + ++L   L ++ +   E  ++   + +     NK L + E   + L+
Sbjct: 1665 KKLKSELKDSQKQCDELHRNLHNLMNENGELKSQNSQLSKDFETNNKKLLNLENAKKQLE 1724

Query: 1311 EKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRT-ENQSYKQMQEQSILN 1369
            +K AD       + +  +++  A                  L   +N++ K+  E     
Sbjct: 1725 QKLADNTKSQNDMFANYQEQIEALGQKIISLEEEDAELNRQLNELKNENNKEEMENKEKE 1784

Query: 1370 INEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQ 1429
             +E  A+  +               +N+   +++E +H+ E  +  + ++  E    L  
Sbjct: 1785 KDELLAEKNRKIDEAEKEFNEQIKHLNEQIQELIEDSHEKENNNENLAKENSELIQKLNS 1844

Query: 1430 RNDEFENVRQQLVEYEKRIE-DLTYEKESELAILRLKMHENANHYETMQKESEIERVKLI 1488
             ++E ++++   V  +  ++ +  Y ++ +  I  L    N    E ++ E EI   K  
Sbjct: 1845 LHEEIKSLKASNVSQKVELDQNKEYIQKRQKDIDLLNEEYNNLFNEKLEFEFEINSQK-- 1902

Query: 1489 EELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVR 1548
            +ELN K   S  +N Q  E++   ++     NE Q  +   + EI +  ++I  L ++  
Sbjct: 1903 DELNNK---SQYINNQKNEIDNLKKQN----NEKQNEIAKLQKEIDSYQEKIDKLISLNE 1955

Query: 1549 ASSSKIQKHVSFASDTKQGRDEQLDNTMNKEL 1580
              ++K+          ++ RD +L++    E+
Sbjct: 1956 EKNNKLTNLAKQQQYAQKNRDLELNDGNENEI 1987



 Score =  167 bits (407), Expect = 2e-39
 Identities = 336/1609 (20%), Positives = 695/1609 (43%), Gaps = 180/1609 (11%)

Query: 99   KQKEILMEKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNAL 158
            K+ EIL +++ +  + +     + +                Q+ D T   N  K + +A 
Sbjct: 368  KEIEILNQRLAEKSDKTLNERISYLEKELSKTLSENETQKTQINDFTSRINKYKAELDAK 427

Query: 159  SVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQM 218
               + ++  ++T   +L+E +  KD+ I A  KA                    +T +  
Sbjct: 428  VDQEAQILTLQTLNTELKESLANKDKEI-ADLKALLDKDLSSNAGSPVKKASKTNTDED- 485

Query: 219  TKMQENFIAMEAEWKDEKQRLLKDIESKDVRISS--LEEANKLLEAARFEISLEHSKLAQ 276
               + N  A++      KQ  LK  E++D++  +  L++ N  L+    + S E+ KL +
Sbjct: 486  ---EVNTSALDVTIDSPKQ--LKG-ENEDLKADNQKLKQENDKLKQDSDKTSQENQKLTE 539

Query: 277  ELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLN- 335
            ELE               L ++S E   ++    E   SL   N   +  K E +E L  
Sbjct: 540  ELENLRKQLAE-------LQEKSKEKGSDDSFSQELNSSLNQVNEAIIQSKDEEIEELKG 592

Query: 336  ----------CQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTAS-KMKS 384
                       Q++Q N++L+ +   +    +  S+     SP+ + K+ +++   K+ +
Sbjct: 593  KLAELNGLFEAQVKQ-NEDLQAENTKLTQALEMFSNNDTSSSPVSAAKNFKHSLDEKIAN 651

Query: 385  PWSQLS-----SETLNQDTDKKINK--NEIAKLEMVIQSLN--KDLVD-KEYVISEKDTX 434
                ++     ++ L  D D+K     N   + E   + +N  K  +D K+  I      
Sbjct: 652  LQDAVNKYREITDNLQNDNDEKAELIVNMEKEAEAFAERINHYKSEIDSKDSEIERLKAE 711

Query: 435  XXXXXXXXXGKDTLIAQL--QLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDE 492
                      K+T   Q+  Q+   Q+    +      N     +IA +Q++L+ + N +
Sbjct: 712  IDKLKGELAAKNTEAEQIKGQISDLQYKLSANGQMQEENNSLAKQIADLQKELENKAN-Q 770

Query: 493  IKDVNVK--------DLIEK-LKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKT 543
            IKD+  +        +L +K + + ++Q  + +++ D  N  + K++S ++ K K++ + 
Sbjct: 771  IKDLESRLNSLNDQNELKQKEIDALKKQFREKSEQFDLLNSEINKLRSENEEKSKEINQ- 829

Query: 544  IDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMI 603
              N + + +  KEI  L  E    SQ++  L +E    +  + +      +E++  KK I
Sbjct: 830  --NKALIEEKTKEIEALKAENAQKSQQINALSQENEQKKKQIDNLS----VENEQKKKQI 883

Query: 604  EMENLA-ETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSV 662
            +  ++  E + K I  L  +     +++  L +K ++ E ++ ++S+ Q++Q   +I ++
Sbjct: 884  DNLSVENEQKKKQIDNLSEENKLNKKQIDDLAEKNEQNEKQINNLSE-QNEQKKKQIDNL 942

Query: 663  HLEE-----QIDALSASKK-----------ELALVIENLKLDKEQLYGT-IKDLENDKED 705
              E      QID LS   K           E+  V+ + ++   +L    + D    K+D
Sbjct: 943  SEENKQNKRQIDDLSEENKLGKEKMNKIESEIRKVVNDTEMTPVRLTSKFVADANEKKKD 1002

Query: 706  IMNKLQNY--IQENMD-LTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDL 762
                L+    + + +D L  KL+++  EK  EL+++    +Q K +    I +K+ E   
Sbjct: 1003 NAKLLEENKALSKAIDELQQKLDELHKEK-DELISQAQKNQQEKEEFGQFIKSKLAEYAD 1061

Query: 763  YIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQL---------GSYLQEKQKAY 813
             +++++ E  +    I  L ++I  M  RR  +E+ +               L+++ +  
Sbjct: 1062 NLKSLDKERKEKDQEINALNDTIEAM--RRQEIEQASHHYKDMSDLHNTNKSLEKQIEEM 1119

Query: 814  SEYTIQEDELVNRLAVLMDHDRVVEKQLLEI---EHENKELQKKNQILLEENQNLQISLS 870
             E    +DE V RL  L + +R +    L I   E EN+EL+K+N+ L E+ + LQ  + 
Sbjct: 1120 KEKVTNDDEEV-RLQ-LQNKEREITASKLMITNKEKENEELKKQNEELKEKTEKLQKEVQ 1177

Query: 871  DMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEI 930
            + +   N+L +     +  E E  K +   +D E N   +  E Q L  + +K   +L+ 
Sbjct: 1178 EKEGEVNSL-KLTFTMNTQELEKQKKEFAAKDTEIN--NLNQEIQKLNQEAEKVTSELQ- 1233

Query: 931  EFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQ-LQEYKNNIENLNMNVEELNKMNLELI 989
                ++ S ++  KV  E  +K  +   Q  A+ +Q+ +++I N+   ++ L K ++E  
Sbjct: 1234 ----KVTSDLQ--KVTEENAKKQEQEEDQSSAEKIQDLQSDIFNMKREIKTL-KDDIENK 1286

Query: 990  DKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESK 1049
            +K +QK    S D T +   E+NKL +   + D+E   L  +    ++   ++    ++ 
Sbjct: 1287 EKEIQK----SKDETSKINEELNKLKSDKSKLDKENRTLKDQFEKQKILVSALQE--QNN 1340

Query: 1050 LAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQ----ILVREQDDQIKELKETKLTFEMN 1105
             ++F  + +N++ ++     +    +Q N E Q    IL  E + +  +++      E  
Sbjct: 1341 QSKFEEENKNLKTQLSAAKSEKSKLQQENTEKQNQIDILTAETERKSNQIRSHLTEIEQL 1400

Query: 1106 IPKTEGMIIS----STIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQS 1161
              K +G   S     T +  S+  N+               K + + +  +     +E  
Sbjct: 1401 KSKLDGQTNSLNDLKTYKQQSEQFNSKLDELQKNLAKAMKEKEEIQTQLTESNKEKEEMQ 1460

Query: 1162 AKLNT------ELQECYTK-IIQLETLNTELTGHDVVNQEQINQLKSKLE---QLNTEND 1211
             KL+       ELQ+ Y + + + E L          N+E   +L  +++   +L+    
Sbjct: 1461 QKLDDGFRQFEELQDSYNQGMSKYEELEQSYNQGMAQNEELKKKLNDEIKDNKELDKNMH 1520

Query: 1212 NLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQ-READFQKTEH---ELRVQLSAFESK 1267
             L+ST  E+ + + +A  QR   + E  KQ  +    +D ++ +    EL  + ++ +S+
Sbjct: 1521 ELMSTNYEIDTQLKAA-KQRIVSLEEEMKQFQSNDHSSDLEQLKSKLIELTKENNSIKSR 1579

Query: 1268 YEQLLD---SVQSSTQE---ETNKIVT-MEQVTSLQNKLQDKEEHL----RNLQEKYADV 1316
             E L++   SV+S   E   E N I + + ++ +  +K + + + L     +L+ +  + 
Sbjct: 1580 NEDLIEENKSVKSKVDELSKENNSIKSKVNELNNENSKSKSRIDELIKANDSLKSQLQER 1639

Query: 1317 INQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTE-NQSYKQMQE--QSILNINEE 1373
             N+IEI++SE+ ++                     L++E   S KQ  E  +++ N+  E
Sbjct: 1640 ANEIEIIKSELAEKS--------KEKETENDEIKKLKSELKDSQKQCDELHRNLHNLMNE 1691

Query: 1374 NAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDE 1433
            N +LK  +               D E    +L + LE    ++ QK  + T     +ND 
Sbjct: 1692 NGELKSQNSQLS----------KDFETNNKKLLN-LENAKKQLEQKLADNT---KSQNDM 1737

Query: 1434 FENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNV 1493
            F N ++Q+    ++I  L  E+++EL   +L   +N N+ E M+ + E E+ +L+ E N 
Sbjct: 1738 FANYQEQIEALGQKIISLE-EEDAELN-RQLNELKNENNKEEMENK-EKEKDELLAEKNR 1794

Query: 1494 KITESVS-LNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRA-SS 1551
            KI E+    N+Q+  LN+ ++E +  ++E +   EN   E   L  ++ +L   +++  +
Sbjct: 1795 KIDEAEKEFNEQIKHLNEQIQELIEDSHEKENNNENLAKENSELIQKLNSLHEEIKSLKA 1854

Query: 1552 SKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDLAMYMLHQRD 1600
            S + + V    + +  +  Q D  +  E  + +   +L+    +  Q+D
Sbjct: 1855 SNVSQKVELDQNKEYIQKRQKDIDLLNEEYNNLFNEKLEFEFEINSQKD 1903



 Score =  153 bits (372), Expect = 3e-35
 Identities = 329/1514 (21%), Positives = 620/1514 (40%), Gaps = 157/1514 (10%)

Query: 154  KDNALSVLQVKMKIMETTILDLQEKINEKDQIIEA--------KNKAT-TXXXXXXXXXX 204
            K+ ALS    +   +E+   +L +KI EKD +I +        ++KA             
Sbjct: 26   KEKALSGALKENLALESKNAELAQKIKEKDILIRSLQEENYKYRSKANQVSREQANEEKI 85

Query: 205  XXXXXXXEDTKQQMTKMQENFIAMEA----EWKDEKQRLLKDIESKDVRISSLEEANKL- 259
                   +    Q T    + ++ +A    + + + ++L  ++E+ +V++ +  +  K  
Sbjct: 86   SQLGLKFQKQLNQKTLQYASQLSAQAKSISDLEAQVKKLNTELENTEVKLQTASKKQKAK 145

Query: 260  LEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIA 319
            L+A   E   +   L + + Q                +Q I+ S  E+ + ++   LE  
Sbjct: 146  LQATIKEKQAQIDTLNERIAQDSILYEESAKQLESY-QQQIQ-SLNEEIKSKDVSILERD 203

Query: 320  N-MTELTKKI-ELLEHLNCQIRQTN---KELENKLATMGTESK-----AVSSPSKKGSPL 369
            N + EL  KI +++  ++ + +Q+     E E  +A +  + K     A    + K S  
Sbjct: 204  NTIRELENKINDIVGKVDQKFKQSKDAIAEKEKIVAQLKKDPKNEGIVAAIEKADKSSSQ 263

Query: 370  ISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIA-KLEMVIQSLNKDLVDKEYVI 428
            ++           KS  +   SE      D  INKN+ A +L  +IQ+ +  + + E  +
Sbjct: 264  LNESVNELQEKLSKSQINGDESEVSASQLDISINKNDSASELCEIIQNKDNRIKELEAAV 323

Query: 429  SEKDTXXXXXXXXXXGKDTLIAQLQLE-HQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQ 487
             E                    Q Q+E H+Q +E     +     E      ++ E+  +
Sbjct: 324  EELKHKPMKMNDIAQNSQENALQSQIEIHEQEIEELQATNQALEKEIEILNQRLAEKSDK 383

Query: 488  ELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNM--IKVKSNHKLKLKQMQKTID 545
             LN+ I  +  K+L + L   E Q TQ+ND     NK    +  K + + ++  +Q T++
Sbjct: 384  TLNERISYLE-KELSKTLSENETQKTQINDFTSRINKYKAELDAKVDQEAQILTLQ-TLN 441

Query: 546  NFSKVSDSN--KEIVRLTEEL-HHLSQKV---------AELEEEKGNLQLHLVDYDSGRM 593
               K S +N  KEI  L   L   LS               +E++ N     V  DS + 
Sbjct: 442  TELKESLANKDKEIADLKALLDKDLSSNAGSPVKKASKTNTDEDEVNTSALDVTIDSPKQ 501

Query: 594  IESDVYKKMIEMENLAE--TRLKAISLLESQKFD-LVQELHILQQKYDEVEDKLADISQL 650
            ++ +      + + L +   +LK  S   SQ+   L +EL  L+++  E+++K     + 
Sbjct: 502  LKGENEDLKADNQKLKQENDKLKQDSDKTSQENQKLTEELENLRKQLAELQEK---SKEK 558

Query: 651  QSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIM--- 707
             SD   S+  +  L +  +A+  SK E    IE LK    +L G  +      ED+    
Sbjct: 559  GSDDSFSQELNSSLNQVNEAIIQSKDE---EIEELKGKLAELNGLFEAQVKQNEDLQAEN 615

Query: 708  NKLQNYIQENMDLTDKLEKMSAEK-----ISELLAKINHEEQSKIQTQFGIDAKIQERDL 762
             KL   ++   +       +SA K     + E +A +        +    +     E+  
Sbjct: 616  TKLTQALEMFSNNDTSSSPVSAAKNFKHSLDEKIANLQDAVNKYREITDNLQNDNDEKAE 675

Query: 763  YIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDE 822
             I N+E E   +  RI   +  I   +     L+ + D+L   L  K     +   Q  +
Sbjct: 676  LIVNMEKEAEAFAERINHYKSEIDSKDSEIERLKAEIDKLKGELAAKNTEAEQIKGQISD 735

Query: 823  LVNRLAV---LMDHDRVVEKQL--LEIEHEN-----KELQKKNQILLEENQNLQISLSDM 872
            L  +L+    + + +  + KQ+  L+ E EN     K+L+ +   L ++N+  Q  +  +
Sbjct: 736  LQYKLSANGQMQEENNSLAKQIADLQKELENKANQIKDLESRLNSLNDQNELKQKEIDAL 795

Query: 873  QQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEF 932
            ++ +    EK+ + DL  SE  K ++   + E   K I ++++ LI +K KEIE L+ E 
Sbjct: 796  KKQFR---EKSEQFDLLNSEINKLRS---ENEEKSKEI-NQNKALIEEKTKEIEALKAE- 847

Query: 933  NTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNM----------NVEELN 982
            N Q    I      NE+ +K I+    L  + ++ K  I+NL++          N+ E N
Sbjct: 848  NAQKSQQINALSQENEQKKKQID---NLSVENEQKKKQIDNLSVENEQKKKQIDNLSEEN 904

Query: 983  KMNLELID------KHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALN------- 1029
            K+N + ID      +  +KQ     +  EQ   +I+ L+   KQ   +I  L+       
Sbjct: 905  KLNKKQIDDLAEKNEQNEKQINNLSEQNEQKKKQIDNLSEENKQNKRQIDDLSEENKLGK 964

Query: 1030 QKINNAQVSYMSMVSDYESKLAQFTTK-LENMEEEMQRVSKQLLDSKQHNEELQILVREQ 1088
            +K+N  +     +V+D E    + T+K + +  E+ +  +K L ++K  ++ +  L ++ 
Sbjct: 965  EKMNKIESEIRKVVNDTEMTPVRLTSKFVADANEKKKDNAKLLEENKALSKAIDELQQKL 1024

Query: 1089 DDQIKELKETKLTFEMNIPKTE--GMIISSTIEPMSDDANNVDXXXXXXXXXXXXL---- 1142
            D+  KE  E     + N  + E  G  I S +   +D+  ++D            L    
Sbjct: 1025 DELHKEKDELISQAQKNQQEKEEFGQFIKSKLAEYADNLKSLDKERKEKDQEINALNDTI 1084

Query: 1143 ------KVQEEEEFIQERSVLQEQSAKLNTELQECYTKI--------IQLETLNTELTGH 1188
                  ++++     ++ S L   +  L  +++E   K+        +QL+    E+T  
Sbjct: 1085 EAMRRQEIEQASHHYKDMSDLHNTNKSLEKQIEEMKEKVTNDDEEVRLQLQNKEREITAS 1144

Query: 1189 D--VVNQEQIN-QLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQ--HL 1243
               + N+E+ N +LK + E+L  + + L   V E    ++S          EL KQ    
Sbjct: 1145 KLMITNKEKENEELKKQNEELKEKTEKLQKEVQEKEGEVNSLKLTFTMNTQELEKQKKEF 1204

Query: 1244 AQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQ---EETNKIVTMEQVTSLQNKLQ 1300
            A ++ +      E++ +L+    K    L  V S  Q   EE  K    E+  S   K+Q
Sbjct: 1205 AAKDTEINNLNQEIQ-KLNQEAEKVTSELQKVTSDLQKVTEENAKKQEQEEDQSSAEKIQ 1263

Query: 1301 DKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYK 1360
            D +  + N++ +   + + IE    EI+  K                    L  EN++ K
Sbjct: 1264 DLQSDIFNMKREIKTLKDDIENKEKEIQKSKDE-TSKINEELNKLKSDKSKLDKENRTLK 1322

Query: 1361 -QMQEQSIL--NINEENAQLK--KSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSE 1415
             Q ++Q IL   + E+N Q K  + +              +  + +  E  +Q+++  +E
Sbjct: 1323 DQFEKQKILVSALQEQNNQSKFEEENKNLKTQLSAAKSEKSKLQQENTEKQNQIDILTAE 1382

Query: 1416 IYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDL-TYEKESELAILRLKMHENANHYE 1474
              +K+++    LT    E E ++ +L      + DL TY+++SE      K+ E   +  
Sbjct: 1383 TERKSNQIRSHLT----EIEQLKSKLDGQTNSLNDLKTYKQQSEQ--FNSKLDELQKNLA 1436

Query: 1475 TMQKESEIERVKLIEELNVKITESVSLN---KQVAELNKALEEEVAKTNEM-----QTAL 1526
               KE E  + +L E    K      L+   +Q  EL  +  + ++K  E+     Q   
Sbjct: 1437 KAMKEKEEIQTQLTESNKEKEEMQQKLDDGFRQFEELQDSYNQGMSKYEELEQSYNQGMA 1496

Query: 1527 ENQEIEIVTLNDEI 1540
            +N+E++   LNDEI
Sbjct: 1497 QNEELK-KKLNDEI 1509



 Score =  139 bits (337), Expect = 5e-31
 Identities = 225/1180 (19%), Positives = 486/1180 (41%), Gaps = 84/1180 (7%)

Query: 215  KQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVR-ISSLEEANKLLEAARFEISLEHSK 273
            K +  + Q N ++ + E K ++   L +   ++ R I  L E NKL +    +I  E  K
Sbjct: 917  KNEQNEKQINNLSEQNEQKKKQIDNLSEENKQNKRQIDDLSEENKLGKEKMNKIESEIRK 976

Query: 274  LAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTK-KIELLE 332
            +  + E                 K+      EE   + +        + EL K K EL+ 
Sbjct: 977  VVNDTEMTPVRLTSKFVADANEKKKDNAKLLEENKALSKAIDELQQKLDELHKEKDELIS 1036

Query: 333  HLNCQIRQTNKE-----LENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWS 387
                Q  Q  KE     +++KLA      K++    K+    I+  +  +T   M+    
Sbjct: 1037 Q--AQKNQQEKEEFGQFIKSKLAEYADNLKSLDKERKEKDQEINALN--DTIEAMRRQEI 1092

Query: 388  QLSSETLNQDTD-KKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKD 446
            + +S      +D    NK+   ++E + + +  D  +    +  K+            K+
Sbjct: 1093 EQASHHYKDMSDLHNTNKSLEKQIEEMKEKVTNDDEEVRLQLQNKEREITASKLMITNKE 1152

Query: 447  TLIAQLQLEHQQHMEGPSLIH--VGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEK 504
                +L+ ++++  E    +   V     +VN +        QEL  + K+   KD   +
Sbjct: 1153 KENEELKKQNEELKEKTEKLQKEVQEKEGEVNSLKLTFTMNTQELEKQKKEFAAKDT--E 1210

Query: 505  LKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEEL 564
            + +  ++I +LN E +     + KV S+ +   ++  K  +     S + K I  L  ++
Sbjct: 1211 INNLNQEIQKLNQEAEKVTSELQKVTSDLQKVTEENAKKQEQEEDQSSAEK-IQDLQSDI 1269

Query: 565  HHLSQKVAELEEEKGNLQLHLV-DYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQK 623
             ++ +++  L+++  N +  +    D    I  ++ K   +   L +         E QK
Sbjct: 1270 FNMKREIKTLKDDIENKEKEIQKSKDETSKINEELNKLKSDKSKLDKENRTLKDQFEKQK 1329

Query: 624  FDLVQELHIL--QQKYDEVEDKL-ADISQLQSDQVCSEIKSVHLEEQIDALSASKKELAL 680
              LV  L     Q K++E    L   +S  +S++   + ++   + QID L+A  +  + 
Sbjct: 1330 I-LVSALQEQNNQSKFEEENKNLKTQLSAAKSEKSKLQQENTEKQNQIDILTAETERKSN 1388

Query: 681  VIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISE---LLA 737
             I +   + EQL   +    N   D+    Q   Q N  L D+L+K  A+ + E   +  
Sbjct: 1389 QIRSHLTEIEQLKSKLDGQTNSLNDLKTYKQQSEQFNSKL-DELQKNLAKAMKEKEEIQT 1447

Query: 738  KINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLE- 796
            ++    + K + Q  +D   ++ +   ++    +SKY+       + +A  E+ +  L  
Sbjct: 1448 QLTESNKEKEEMQQKLDDGFRQFEELQDSYNQGMSKYEELEQSYNQGMAQNEELKKKLND 1507

Query: 797  --RKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLM---------DHDRVVEK---QLL 842
              +   +L   + E      E   Q      R+  L          DH   +E+   +L+
Sbjct: 1508 EIKDNKELDKNMHELMSTNYEIDTQLKAAKQRIVSLEEEMKQFQSNDHSSDLEQLKSKLI 1567

Query: 843  EIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRD 902
            E+  EN  ++ +N+ L+EEN++++  + ++ +  N++  K N  +   S+S     +L  
Sbjct: 1568 ELTKENNSIKSRNEDLIEENKSVKSKVDELSKENNSIKSKVNELNNENSKSKSRIDELIK 1627

Query: 903  LESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQ------IESAIRDKKVLNEKYEKNIEY 956
               +LK    E    I   K E+ +   E  T+      ++S ++D +   ++  +N+  
Sbjct: 1628 ANDSLKSQLQERANEIEIIKSELAEKSKEKETENDEIKKLKSELKDSQKQCDELHRNLHN 1687

Query: 957  VT----QLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEIN 1012
            +     +L++Q  +   + E  N  +  L     +L  K     ++Q+ D    Y  +I 
Sbjct: 1688 LMNENGELKSQNSQLSKDFETNNKKLLNLENAKKQLEQKLADNTKSQN-DMFANYQEQIE 1746

Query: 1013 KLNALLKQKDEEIIALNQKIN-----NAQVSYMSMVSDYESKLAQFTTKLENMEEEM--- 1064
             L   +   +EE   LN+++N     N +    +   + +  LA+   K++  E+E    
Sbjct: 1747 ALGQKIISLEEEDAELNRQLNELKNENNKEEMENKEKEKDELLAEKNRKIDEAEKEFNEQ 1806

Query: 1065 -----QRVSKQLLDSKQHNEELQILVREQDDQIKEL----KETKLTFEMNIPKTEGMIIS 1115
                 +++ + + DS +     + L +E  + I++L    +E K     N+  ++ + + 
Sbjct: 1807 IKHLNEQIQELIEDSHEKENNNENLAKENSELIQKLNSLHEEIKSLKASNV--SQKVELD 1864

Query: 1116 STIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKI 1175
               E +     ++D             K++ E E   ++  L  +S  +N +  E    I
Sbjct: 1865 QNKEYIQKRQKDIDLLNEEYNNLFNE-KLEFEFEINSQKDELNNKSQYINNQKNE----I 1919

Query: 1176 IQLETLNTELTGHDVVNQEQINQLKSKLEQ---LNTENDNLLSTVAELRSSISSAVDQRG 1232
              L+  N E        Q++I+  + K+++   LN E +N L+ +A+ +       D   
Sbjct: 1920 DNLKKQNNEKQNEIAKLQKEIDSYQEKIDKLISLNEEKNNKLTNLAKQQQYAQKNRDLEL 1979

Query: 1233 FEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQ-SSTQEETNKIVTMEQ 1291
             +  E     L Q  A  Q+  ++L  + +    + E++L  ++ +S+  + N++++ ++
Sbjct: 1980 NDGNENEISELRQNNAKLQRKCNKLVEEKAQLAEQLEKVLTLMKNNSSNPQGNQVLSNDE 2039

Query: 1292 VTSL----QNKLQDKEEHLRNLQEKYADVINQIEILRSEI 1327
            +TSL    Q+++ ++E+   +L   Y +VI +++   +++
Sbjct: 2040 LTSLLKQKQSEVSEREKQFNSLLILYDNVIKELKEANAKV 2079



 Score =  135 bits (326), Expect = 1e-29
 Identities = 262/1387 (18%), Positives = 587/1387 (42%), Gaps = 115/1387 (8%)

Query: 233  KDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXX 292
            + +   L + I+ KD+ I SL+E N    +   ++S E +   +++ Q            
Sbjct: 41   ESKNAELAQKIKEKDILIRSLQEENYKYRSKANQVSREQAN-EEKISQ----------LG 89

Query: 293  XXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIEL-LEHLNCQIRQTNKELENKL-A 350
                KQ  + + +  +++  +    I+++    KK+   LE+   +++  +K+ + KL A
Sbjct: 90   LKFQKQLNQKTLQYASQLSAQAK-SISDLEAQVKKLNTELENTEVKLQTASKKQKAKLQA 148

Query: 351  TMGTESKAVSSPSKKGSPLISRKS--GRNTASKMKSPWSQLSSETLNQDTDKKINKNEIA 408
            T+  +   + + +++    I++ S     +A +++S   Q+ S  LN++   K     I 
Sbjct: 149  TIKEKQAQIDTLNER----IAQDSILYEESAKQLESYQQQIQS--LNEEIKSK--DVSIL 200

Query: 409  KLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHV 468
            + +  I+ L   + D   ++ + D            K+ ++AQL+ + +      ++   
Sbjct: 201  ERDNTIRELENKIND---IVGKVDQKFKQSKDAIAEKEKIVAQLKKDPKNEGIVAAIEKA 257

Query: 469  GTNTEDVNE-IAKVQEQL-KQELNDEIKDVNVKDL---IEKLKSAEE--QITQLND---- 517
              ++  +NE + ++QE+L K ++N +  +V+   L   I K  SA E  +I Q  D    
Sbjct: 258  DKSSSQLNESVNELQEKLSKSQINGDESEVSASQLDISINKNDSASELCEIIQNKDNRIK 317

Query: 518  EIDAANKNM-IKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLT-----EELHHLSQKV 571
            E++AA + +  K    + +     +  + +  ++ +   E ++ T     +E+  L+Q++
Sbjct: 318  ELEAAVEELKHKPMKMNDIAQNSQENALQSQIEIHEQEIEELQATNQALEKEIEILNQRL 377

Query: 572  AELEEEKGNLQLHLVDYD-SGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQEL 630
            AE  ++  N ++  ++ + S  + E++  K  I   N   +R+         K D   ++
Sbjct: 378  AEKSDKTLNERISYLEKELSKTLSENETQKTQI---NDFTSRINKYKAELDAKVDQEAQI 434

Query: 631  HILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSAS--KKELALVIENLKLD 688
              LQ    E+++ LA+      D+  +++K++ L++ + + + S  KK      +  +++
Sbjct: 435  LTLQTLNTELKESLAN-----KDKEIADLKAL-LDKDLSSNAGSPVKKASKTNTDEDEVN 488

Query: 689  KEQLYGTI---KDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQS 745
               L  TI   K L+ + ED+    Q   QEN    DKL K  ++K S+   K+  EE  
Sbjct: 489  TSALDVTIDSPKQLKGENEDLKADNQKLKQEN----DKL-KQDSDKTSQENQKLT-EELE 542

Query: 746  KIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRY-SLERKADQLGS 804
             ++ Q    A++QE+     + +S   +  S + ++ E+I   +D     L+ K  +L  
Sbjct: 543  NLRKQL---AELQEKSKEKGSDDSFSQELNSSLNQVNEAIIQSKDEEIEELKGKLAELNG 599

Query: 805  YLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVE--KQLLEIEHENKELQKKNQILLEEN 862
              + + K   +   +  +L   L +  ++D            +H   E     Q  + + 
Sbjct: 600  LFEAQVKQNEDLQAENTKLTQALEMFSNNDTSSSPVSAAKNFKHSLDEKIANLQDAVNKY 659

Query: 863  QNLQISL-SDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTL---I 918
            + +  +L +D  +    +V      +        Y++++   +S ++R+  E   L   +
Sbjct: 660  REITDNLQNDNDEKAELIVNMEKEAEAFAERINHYKSEIDSKDSEIERLKAEIDKLKGEL 719

Query: 919  VQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNV 978
              K  E E ++ +  + ++  +     + E+     + +  L+ +L+   N I++L   +
Sbjct: 720  AAKNTEAEQIKGQI-SDLQYKLSANGQMQEENNSLAKQIADLQKELENKANQIKDLESRL 778

Query: 979  EELNKMNLELIDKHVQKQQTQSPDYTEQY--IN-EINKLNALLKQKDEEIIALNQKINNA 1035
              LN  N EL  K +   + Q  + +EQ+  +N EINKL +  ++K +EI      I   
Sbjct: 779  NSLNDQN-ELKQKEIDALKKQFREKSEQFDLLNSEINKLRSENEEKSKEINQNKALIEEK 837

Query: 1036 QVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKEL 1095
                 ++ ++   K  Q     +  E++ +++    ++++Q  +++  L  E + + K++
Sbjct: 838  TKEIEALKAENAQKSQQINALSQENEQKKKQIDNLSVENEQKKKQIDNLSVENEQKKKQI 897

Query: 1096 KETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERS 1155
                L+ E  + K +   ++   E      NN+             L  +E ++  ++  
Sbjct: 898  --DNLSEENKLNKKQIDDLAEKNEQNEKQINNLSEQNEQKKKQIDNLS-EENKQNKRQID 954

Query: 1156 VLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLS 1215
             L E++ KL  E        I+    +TE+T   +      ++  +   +   +N  LL 
Sbjct: 955  DLSEEN-KLGKEKMNKIESEIRKVVNDTEMTPVRLT-----SKFVADANEKKKDNAKLL- 1007

Query: 1216 TVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSV 1275
               E   ++S A+D+   ++ EL K+   +  +  QK + E        +SK  +  D++
Sbjct: 1008 ---EENKALSKAIDELQQKLDELHKEK-DELISQAQKNQQEKEEFGQFIKSKLAEYADNL 1063

Query: 1276 QSSTQEETNKIVTMEQVTSLQNKLQDKE-EHLRNLQEKYADVINQIEILRSEIEDEKVAF 1334
            +S  +E   K   +  +      ++ +E E   +  +  +D+ N  + L  +IE+ K   
Sbjct: 1064 KSLDKERKEKDQEINALNDTIEAMRRQEIEQASHHYKDMSDLHNTNKSLEKQIEEMK--- 1120

Query: 1335 XXXXXXXXXXXXXXXXDLRTENQSYK-QMQEQSILNINEENAQLKKSSXXXXXXXXXXXX 1393
                             L+ +N+  +    +  I N  +EN +LKK +            
Sbjct: 1121 ------EKVTNDDEEVRLQLQNKEREITASKLMITNKEKENEELKKQNEELKEKTEKLQK 1174

Query: 1394 RVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTY 1453
             V + E +V  L     +   E+ ++  E+      ++ E  N+ Q++ +  +  E +T 
Sbjct: 1175 EVQEKEGEVNSLKLTFTMNTQELEKQKKEF----AAKDTEINNLNQEIQKLNQEAEKVTS 1230

Query: 1454 EKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALE 1513
            E +   + L+    ENA   E  + +S  E+++ ++     +   +   K   E NK  E
Sbjct: 1231 ELQKVTSDLQKVTEENAKKQEQEEDQSSAEKIQDLQSDIFNMKREIKTLKDDIE-NK--E 1287

Query: 1514 EEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLD 1573
            +E+ K+ + +T+  N+E+    L  + + L    R    + +K     S  ++  ++   
Sbjct: 1288 KEIQKSKD-ETSKINEELN--KLKSDKSKLDKENRTLKDQFEKQKILVSALQEQNNQSKF 1344

Query: 1574 NTMNKEL 1580
               NK L
Sbjct: 1345 EEENKNL 1351



 Score = 80.6 bits (190), Expect = 3e-13
 Identities = 151/773 (19%), Positives = 301/773 (38%), Gaps = 73/773 (9%)

Query: 836  VVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTK 895
            V EK L     EN  L+ KN  L ++ +   I +  +Q+       KAN+    ++   K
Sbjct: 25   VKEKALSGALKENLALESKNAELAQKIKEKDILIRSLQEENYKYRSKANQVSREQANEEK 84

Query: 896  YQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIE---FNTQIE--------------- 937
                    +  L + T ++ + +  + K I DLE +    NT++E               
Sbjct: 85   ISQLGLKFQKQLNQKTLQYASQLSAQAKSISDLEAQVKKLNTELENTEVKLQTASKKQKA 144

Query: 938  ---SAIRDKK----VLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELID 990
               + I++K+     LNE+  ++     +   QL+ Y+  I++LN  ++  +   LE  D
Sbjct: 145  KLQATIKEKQAQIDTLNERIAQDSILYEESAKQLESYQQQIQSLNEEIKSKDVSILER-D 203

Query: 991  KHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKL 1050
              +++ + +  D   +   +  +    + +K++ +  L +   N  +  ++ +   +   
Sbjct: 204  NTIRELENKINDIVGKVDQKFKQSKDAIAEKEKIVAQLKKDPKNEGI--VAAIEKADKSS 261

Query: 1051 AQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTE 1110
            +Q    +  ++E++ +      +S+    +L I +  ++D   EL E     +  I + E
Sbjct: 262  SQLNESVNELQEKLSKSQINGDESEVSASQLDISI-NKNDSASELCEIIQNKDNRIKELE 320

Query: 1111 GMIISSTIEP--MSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTEL 1168
              +     +P  M+D A N              +  QE EE       L+++   LN  L
Sbjct: 321  AAVEELKHKPMKMNDIAQN---SQENALQSQIEIHEQEIEELQATNQALEKEIEILNQRL 377

Query: 1169 QECYTKII--QLETLNTELT---GHDVVNQEQINQLKSKLEQLNTENDNLLS------TV 1217
             E   K +  ++  L  EL+     +   + QIN   S++ +   E D  +       T+
Sbjct: 378  AEKSDKTLNERISYLEKELSKTLSENETQKTQINDFTSRINKYKAELDAKVDQEAQILTL 437

Query: 1218 AELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQS 1277
              L + +  ++  +  EIA+L     A  + D          + S   +  +++  S   
Sbjct: 438  QTLNTELKESLANKDKEIADL----KALLDKDLSSNAGSPVKKASKTNTDEDEVNTSALD 493

Query: 1278 STQEETNKIV-TMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXX 1336
             T +   ++    E + +   KL+ + + L+   +K +    + + L  E+E+ +     
Sbjct: 494  VTIDSPKQLKGENEDLKADNQKLKQENDKLKQDSDKTS---QENQKLTEELENLRKQLAE 550

Query: 1337 XXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVN 1396
                            +  N S  Q+ E  I + +EE  +LK               +  
Sbjct: 551  LQEKSKEKGSDDSFS-QELNSSLNQVNEAIIQSKDEEIEELKGKLAELNGLFEAQVKQNE 609

Query: 1397 DAEAKVLELTHQLEL-KDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEK 1455
            D +A+  +LT  LE+  +++                DE     Q  V   + I D     
Sbjct: 610  DLQAENTKLTQALEMFSNNDTSSSPVSAAKNFKHSLDEKIANLQDAVNKYREITDNLQND 669

Query: 1456 ESELAILRLKMHENA-------NHY--ETMQKESEIERV-----KLIEELNVKITESVSL 1501
              E A L + M + A       NHY  E   K+SEIER+     KL  EL  K TE+  +
Sbjct: 670  NDEKAELIVNMEKEAEAFAERINHYKSEIDSKDSEIERLKAEIDKLKGELAAKNTEAEQI 729

Query: 1502 NKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKI 1554
              Q+++    L+ +++   +MQ    +   +I  L  E+ N  N ++   S++
Sbjct: 730  KGQISD----LQYKLSANGQMQEENNSLAKQIADLQKELENKANQIKDLESRL 778



 Score = 80.6 bits (190), Expect = 3e-13
 Identities = 107/556 (19%), Positives = 247/556 (44%), Gaps = 57/556 (10%)

Query: 319  ANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNT 378
            + + ELTK+   ++  N  + + NK +++K+  +  E+ ++ S        ++  +  N+
Sbjct: 1564 SKLIELTKENNSIKSRNEDLIEENKSVKSKVDELSKENNSIKSK-------VNELNNENS 1616

Query: 379  ASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEY--VISE-KDTXX 435
             SK +      ++++L     ++ N+ EI K E+  +S  K+  + E   + SE KD+  
Sbjct: 1617 KSKSRIDELIKANDSLKSQLQERANEIEIIKSELAEKSKEKETENDEIKKLKSELKDSQK 1676

Query: 436  XXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKD 495
                      + +    +L+ Q            TN + +  +   ++QL+Q+L D  K 
Sbjct: 1677 QCDELHRNLHNLMNENGELKSQNSQLSKDF---ETNNKKLLNLENAKKQLEQKLADNTKS 1733

Query: 496  VN--VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKS-NHKLKLKQMQKTIDNF----- 547
             N    +  E++++  ++I  L +E    N+ + ++K+ N+K +++  +K  D       
Sbjct: 1734 QNDMFANYQEQIEALGQKIISLEEEDAELNRQLNELKNENNKEEMENKEKEKDELLAEKN 1793

Query: 548  SKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMEN 607
             K+ ++ KE     E++ HL++++ EL E+      H  + ++  + + +   ++I+  N
Sbjct: 1794 RKIDEAEKEF---NEQIKHLNEQIQELIEDS-----HEKENNNENLAKEN--SELIQKLN 1843

Query: 608  LAETRLKAISLLE-SQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEE 666
                 +K++     SQK +L Q    +Q++  +++    + + L ++++  E +    ++
Sbjct: 1844 SLHEEIKSLKASNVSQKVELDQNKEYIQKRQKDIDLLNEEYNNLFNEKLEFEFEINSQKD 1903

Query: 667  QIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEK 726
            +++  S         I+NLK    +    I  L+ + +    K+   I  N +  +KL  
Sbjct: 1904 ELNNKSQYINNQKNEIDNLKKQNNEKQNEIAKLQKEIDSYQEKIDKLISLNEEKNNKLTN 1963

Query: 727  MS-----AEKISELLAKINHEE------QSKIQTQFGIDAKIQERDLYIENIESELSKYK 775
            ++     A+K  +L     +E       Q+  + Q   +  ++E+    E +E  L+  K
Sbjct: 1964 LAKQQQYAQKNRDLELNDGNENEISELRQNNAKLQRKCNKLVEEKAQLAEQLEKVLTLMK 2023

Query: 776  SRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRL-------- 827
            +     + +  +  D   SL +   Q  S + E++K ++   I  D ++  L        
Sbjct: 2024 NNSSNPQGNQVLSNDELTSLLK---QKQSEVSEREKQFNSLLILYDNVIKELKEANAKVA 2080

Query: 828  ---AVLMDHDRVVEKQ 840
               A  ++H R+VEK+
Sbjct: 2081 RLEAAAVNHARIVEKR 2096


>UniRef50_A2FKT9 Cluster: Viral A-type inclusion protein, putative;
            n=1; Trichomonas vaginalis G3|Rep: Viral A-type inclusion
            protein, putative - Trichomonas vaginalis G3
          Length = 2114

 Score =  174 bits (424), Expect = 1e-41
 Identities = 280/1374 (20%), Positives = 610/1374 (44%), Gaps = 136/1374 (9%)

Query: 220  KMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHS-KLAQEL 278
            K +  F  ++ +++D   ++L D + +++   +L+  N L      +I +++    A++ 
Sbjct: 770  KFKNEFEFIKKQYEDNI-KVLNDRQQEEIDQLNLQNKNMLNVLKNEKIIVQNQLNEARQR 828

Query: 279  EQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIEL-LEHLNCQ 337
             +                +  I+   E++ E E+K S    N   L  + +  +E L  +
Sbjct: 829  VKDLEDKNQILLDQKQTREDGIDRIEEKQREYEDKISSLEQNFDHLNLEHQKDMEKLQAE 888

Query: 338  IRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQD 397
            I++   E +  +  M  +  + +   KK + +IS    RN+  + K+         L Q+
Sbjct: 889  IKKLESEKQQLINKMMNDHNS-NKDQKKMNEIISDLQKRNSEIEQKNQ----EINQLKQE 943

Query: 398  TDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQ 457
             D++  K ++  L+     + K+ ++ E +IS+ +             +  +    +   
Sbjct: 944  IDQE--KEKVTNLDTEKSKMQKEKINMEQIISQNEQEKKELQQVITEYEQSLNDFNINSI 1001

Query: 458  QHMEGPSLIH--VGTNTEDVNEIAKVQEQLKQELNDEIKDVNVK--DLIEKLKSAEEQIT 513
            +  E    +   + +   +++   + + + K++  +EI  +N K  DL  + K   EQI 
Sbjct: 1002 KQKEQIKTLQNQIQSLNSEISNFNEKENEEKEKHKNEIDKLNQKLNDLQNQRKILHEQI- 1060

Query: 514  QLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNF-SKVS----DSNKEIVRLTEELHHLS 568
             L +E      N I+ K N +L+ K+ +KTI++F +K+     +S+++I +  +E+   +
Sbjct: 1061 DLQNEHHKKEMNDIQSKIN-ELE-KEKKKTIEDFQNKIKNIQEESDRKIKQNMDEIESKN 1118

Query: 569  QKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQ 628
            +K+ +LE+E+ N Q  +          SD Y++++   NL   +L  +     Q  +L+ 
Sbjct: 1119 KKIQDLEQERNNQQKMIEKLAKDN---SDEYEEVV---NLFNQQLDNLRQNNRQNENLIA 1172

Query: 629  ELHIL-QQKYDEVEDKLADISQLQSDQVCSEIKSVH---LEEQIDALSASKKELALVIEN 684
             L    ++K  E+E  + +IS+LQ     SEIK+ +    E  ++    +K+++A  I++
Sbjct: 1173 SLRSSNEEKQKEIEKLVQEISELQKQ--ISEIKNQNDFETERLLNESKEAKQKMASKIKD 1230

Query: 685  LKLDKEQLYGTIKDLENDKEDI----MNKLQNYIQENMDLTDKLEKMSAEKISELLAKIN 740
            L+ DK+ L   I+ L+   +++    M++ +++ +E    ++K+++++ E+I +L  +IN
Sbjct: 1231 LESDKKFLQQEIEKLKRINDNLNQQNMSQKRDFDEELSQKSNKIKELN-ERIIDLQKQIN 1289

Query: 741  HEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKAD 800
            +++ S++ ++      +Q++   ++ +  EL   KS    L++ I+ +   R  L+++AD
Sbjct: 1290 NDDLSQLNSRLH---NLQKQKDEVDQLNIELKNDKSN---LQKQISSLAKEREDLKQQAD 1343

Query: 801  QLGSYLQ-------EKQKAYSEYTIQEDELVNRL-AVLMDHDRVV---EKQLLEIEHENK 849
             L  Y +       EK+         E ++ N+       +D ++   +KQL  +++  +
Sbjct: 1344 SLNDYKKRVSDLEKEKENLVQNIKNMEIQISNQKDGNQPKNDALITALQKQLESMKNRRE 1403

Query: 850  ELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKR 909
             ++K    L  +NQ L     ++++    L+ K    +L   E  K++TQ R L  +L++
Sbjct: 1404 NIEKD---LKAQNQQLVDKNKELEEKVQELMHKITELNL---ELCKFKTQQRQLNRDLEK 1457

Query: 910  ITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKN 969
            I  E++ L    K    D E+  + +IE      + +N    K IE +++ EA   + +N
Sbjct: 1458 IQQENEKL----KNAKTDSELNSSKRIEFLENQLENVN----KQIEELSKAEAN--KIQN 1507

Query: 970  NIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEIN-KLNALLKQK---DEEI 1025
             ++  N   E+L K   EL +K +   Q          +NE+  K+  L K+K   D++I
Sbjct: 1508 QLDMKNKENEQLQKEKQELAEK-INNLQI--------ILNELQIKIEILEKEKSDLDKQI 1558

Query: 1026 IALNQKINNAQVSYMSM---VSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQ 1082
              LN+ +NN++     +   +   +++ +   ++L  ++ +     K + +  Q N+EL 
Sbjct: 1559 EKLNEDLNNSESKNKEIERQIFQLQNRKSDVNSQLNTLQVDKDYYQKIIDELHQKNDELV 1618

Query: 1083 ILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXL 1142
              ++   DQ+ EL + K   ++N    + +   + ++ + D                  L
Sbjct: 1619 QRIKVLVDQLNELLKVK--DQLNGSNEDLLKKITELQGLKDQLEE------------NYL 1664

Query: 1143 KVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSK 1202
            K++++ + I E   ++EQ   +N  L+E   +I +LE +       +    E+I+    K
Sbjct: 1665 KLKDDNQTISE---MKEQLDDVNELLKE---RISELEGIQES----NESKIEEISNELDK 1714

Query: 1203 LEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLS 1262
             + + T+ +NL  T  +  S   S + +R   + E  K+ L  +  + Q+   EL+   +
Sbjct: 1715 YKSMTTDLNNL--TEIDNISIDGSGIKERNDSLNEKIKE-LQDKIDELQRNYDELQSLHT 1771

Query: 1263 AFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEI 1322
              + +  ++ DS       +    +  + +     KL   E  L  L + + D++     
Sbjct: 1772 QVKDENSRIKDSYNELNASKEKLQINFDNLDQNNKKL---ESDLDKLNKSFNDLLEN--- 1825

Query: 1323 LRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSX 1382
               +++D                     D++  N++  Q+ E +   +   N  L +   
Sbjct: 1826 -NQQLQDNNNQLNEEKNKLQSDFDNSQNDIKKFNENINQLCESNN-KLENANKDLNERQK 1883

Query: 1383 XXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVR---Q 1439
                       +V +   ++ +L  + E  D E      E  I   Q +DE + +    Q
Sbjct: 1884 ILERDNNELKRQVENLMGEINKLNEEKENLDRERKSLEGEL-IKQNQNDDEIKRLNDEIQ 1942

Query: 1440 QLVEYEKRIEDLTYEKESELAILR--LKMHENANHYETMQKESEIERVK-------LIEE 1490
             L  ++K +E+    KE++L+ L   L    NA + +    + +IE +K       LIE+
Sbjct: 1943 SLNHHKKELEENLKLKENQLSDLSNTLSTISNALNSQISGLKEQIEELKQKQNPNELIEK 2002

Query: 1491 LNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQ 1544
            LN    E   L + + + +K  EE   + +E++   +N   EI  LN +  +L+
Sbjct: 2003 LNELQEEKKKLEQDITDKDKLNEELQKRVDELEKEKQNHYEEIQQLNLKTRDLE 2056



 Score =  167 bits (407), Expect = 2e-39
 Identities = 261/1248 (20%), Positives = 530/1248 (42%), Gaps = 106/1248 (8%)

Query: 411  EMVIQSLNKDL--VDKEY--VISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLI 466
            EM ++ LN  L  +DK+   + SE D+            +  I++L+ + + + +    +
Sbjct: 604  EMEVEMLNNQLSMIDKQRQNLQSELDSVNHKHYETTNMLNDKISKLESDKKSYQDKYESL 663

Query: 467  HVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNM 526
                +  ++    K  E+  ++L   + D N++DL +  K  +    +L +E     K+ 
Sbjct: 664  SKELDY-NIENARKEYEEKTKDLR-RLYDKNIQDLSDLQKGKQILERKLEEE---EKKHE 718

Query: 527  IKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKV-AELEEE-KGNLQLH 584
             + +       +++++ ++   ++    K I    +EL    Q V  ++ E+ K   +  
Sbjct: 719  EEREWERNKSQEEIKRGLNRIIELESQQKRIYIENDELKERLQTVYIDVSEKFKNEFEFI 778

Query: 585  LVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDK- 643
               Y+    + +D  ++ I+  NL    +  +++L+++K  +  +L+  +Q+  ++EDK 
Sbjct: 779  KKQYEDNIKVLNDRQQEEIDQLNLQNKNM--LNVLKNEKIIVQNQLNEARQRVKDLEDKN 836

Query: 644  --LADISQLQSDQVCS-EIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLE 700
              L D  Q + D +   E K    E++I +L  +   L L  E+ K D E+L   IK LE
Sbjct: 837  QILLDQKQTREDGIDRIEEKQREYEDKISSLEQNFDHLNL--EHQK-DMEKLQAEIKKLE 893

Query: 701  NDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQER 760
            ++K+ ++NK+ N    N D     +K   E IS+L  K N E + K Q    +  +I + 
Sbjct: 894  SEKQQLINKMMNDHNSNKD-----QKKMNEIISDL-QKRNSEIEQKNQEINQLKQEIDQE 947

Query: 761  DLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQE 820
               + N+++E SK +     +E+ I+  E  +  L++   +    L +      +   Q 
Sbjct: 948  KEKVTNLDTEKSKMQKEKINMEQIISQNEQEKKELQQVITEYEQSLNDFNINSIKQKEQI 1007

Query: 821  DELVNRLAVLMDH-DRVVEKQLLEIEHENKELQKKNQIL--LEENQNLQISLSDMQ-QHY 876
              L N++  L        EK+  E E    E+ K NQ L  L+  + +     D+Q +H+
Sbjct: 1008 KTLQNQIQSLNSEISNFNEKENEEKEKHKNEIDKLNQKLNDLQNQRKILHEQIDLQNEHH 1067

Query: 877  ----NALVEKANRTDLAESESTK-YQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIE 931
                N +  K N  +  + ++ + +Q ++++++    R   ++   I  K K+I+DLE E
Sbjct: 1068 KKEMNDIQSKINELEKEKKKTIEDFQNKIKNIQEESDRKIKQNMDEIESKNKKIQDLEQE 1127

Query: 932  FNTQ---IESAIRD-----KKVLN----------EKYEKNIEYVTQLEAQLQEYKNNIEN 973
             N Q   IE   +D     ++V+N          +   +N   +  L +  +E +  IE 
Sbjct: 1128 RNNQQKMIEKLAKDNSDEYEEVVNLFNQQLDNLRQNNRQNENLIASLRSSNEEKQKEIEK 1187

Query: 974  LNMNVEELNKMNLEL---IDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQ 1030
            L   + EL K   E+    D   ++   +S +  ++  ++I  L +  K   +EI  L +
Sbjct: 1188 LVQEISELQKQISEIKNQNDFETERLLNESKEAKQKMASKIKDLESDKKFLQQEIEKLKR 1247

Query: 1031 KINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLL--DSKQHNEELQILVREQ 1088
              +N     MS   D++ +L+Q + K++ + E +  + KQ+   D  Q N  L  L +++
Sbjct: 1248 INDNLNQQNMSQKRDFDEELSQKSNKIKELNERIIDLQKQINNDDLSQLNSRLHNLQKQK 1307

Query: 1089 D--DQIK-ELKETKLTFEMNIPK--TEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLK 1143
            D  DQ+  ELK  K   +  I     E   +    + ++D    V             +K
Sbjct: 1308 DEVDQLNIELKNDKSNLQKQISSLAKEREDLKQQADSLNDYKKRVSDLEKEKENLVQNIK 1367

Query: 1144 VQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKL 1203
               E +   ++   Q ++  L T LQ+      QLE++       +   + Q  QL  K 
Sbjct: 1368 -NMEIQISNQKDGNQPKNDALITALQK------QLESMKNRRENIEKDLKAQNQQLVDKN 1420

Query: 1204 EQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELR--VQL 1261
            ++L  +   L+  + EL   +     Q+     +L K      +    KT+ EL    ++
Sbjct: 1421 KELEEKVQELMHKITELNLELCKFKTQQRQLNRDLEKIQQENEKLKNAKTDSELNSSKRI 1480

Query: 1262 SAFESKYEQLLDSVQSSTQEETNKI-----VTMEQVTSLQNKLQDKEEHLRNLQ------ 1310
               E++ E +   ++  ++ E NKI     +  ++   LQ + Q+  E + NLQ      
Sbjct: 1481 EFLENQLENVNKQIEELSKAEANKIQNQLDMKNKENEQLQKEKQELAEKINNLQIILNEL 1540

Query: 1311 --------EKYADVINQIEIL-----RSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQ 1357
                    ++ +D+  QIE L      SE +++++                  +    ++
Sbjct: 1541 QIKIEILEKEKSDLDKQIEKLNEDLNNSESKNKEIERQIFQLQNRKSDVNSQLNTLQVDK 1600

Query: 1358 SYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLE-LKD--S 1414
             Y Q     +   N+E  Q  K              ++N +   +L+   +L+ LKD   
Sbjct: 1601 DYYQKIIDELHQKNDELVQRIKVLVDQLNELLKVKDQLNGSNEDLLKKITELQGLKDQLE 1660

Query: 1415 EIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYE 1474
            E Y K  +   T+++  ++ ++V + L E    +E +    ES++  +  ++ +  +   
Sbjct: 1661 ENYLKLKDDNQTISEMKEQLDDVNELLKERISELEGIQESNESKIEEISNELDKYKSMTT 1720

Query: 1475 TMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIV 1534
             +   +EI+ +  I+   +K   + SLN+++ EL   ++E     +E+Q+       ++ 
Sbjct: 1721 DLNNLTEIDNIS-IDGSGIK-ERNDSLNEKIKELQDKIDELQRNYDELQSL----HTQVK 1774

Query: 1535 TLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLD 1582
              N  I +  N + AS  K+Q +        +  +  LD  +NK   D
Sbjct: 1775 DENSRIKDSYNELNASKEKLQINFDNLDQNNKKLESDLDK-LNKSFND 1821



 Score =  155 bits (376), Expect = 1e-35
 Identities = 236/1117 (21%), Positives = 484/1117 (43%), Gaps = 107/1117 (9%)

Query: 149  NTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQI----IEAKNKATTXXXXXXXXXX 204
            N+IK+K+  +  LQ +++ + + I +  EK NE+ +     I+  N+             
Sbjct: 999  NSIKQKEQ-IKTLQNQIQSLNSEISNFNEKENEEKEKHKNEIDKLNQKLNDLQNQRKILH 1057

Query: 205  XXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAAR 264
                   E  K++M  +Q     +E E    K++ ++D ++K   I   EE+++ ++   
Sbjct: 1058 EQIDLQNEHHKKEMNDIQSKINELEKE----KKKTIEDFQNKIKNIQ--EESDRKIKQNM 1111

Query: 265  FEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTEL 324
             EI  ++ K+ Q+LEQ              LAK +     +E  E+    + ++ N+ + 
Sbjct: 1112 DEIESKNKKI-QDLEQERNNQQKMIEK---LAKDN----SDEYEEVVNLFNQQLDNLRQN 1163

Query: 325  TKKIE-LLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMK 383
             ++ E L+  L     +  KE+E  +  +    K +S    +      R    +  +K K
Sbjct: 1164 NRQNENLIASLRSSNEEKQKEIEKLVQEISELQKQISEIKNQNDFETERLLNESKEAKQK 1223

Query: 384  SPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNK-----------DLVDKEYVISEKD 432
                 ++S+  + ++DKK  + EI KL+ +  +LN+           +L  K   I E +
Sbjct: 1224 -----MASKIKDLESDKKFLQQEIEKLKRINDNLNQQNMSQKRDFDEELSQKSNKIKELN 1278

Query: 433  TXXXXXXXXXXGKDTLIAQLQLEHQQHMEGP------SLIHVGTNTE-DVNEIAKVQEQL 485
                         D      +L + Q  +         L +  +N +  ++ +AK +E L
Sbjct: 1279 ERIIDLQKQINNDDLSQLNSRLHNLQKQKDEVDQLNIELKNDKSNLQKQISSLAKEREDL 1338

Query: 486  KQE---LNDEIKDVN-----VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKL 537
            KQ+   LND  K V+      ++L++ +K+ E QI+   D     N  +I         +
Sbjct: 1339 KQQADSLNDYKKRVSDLEKEKENLVQNIKNMEIQISNQKDGNQPKNDALITALQKQLESM 1398

Query: 538  KQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSG-RMIES 596
            K  ++ I+   K    N+++V   +EL    +KV EL  +   L L L  + +  R +  
Sbjct: 1399 KNRRENIEKDLKAQ--NQQLVDKNKELE---EKVQELMHKITELNLELCKFKTQQRQLNR 1453

Query: 597  DVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVC 656
            D+ K  I+ EN      K  S L S K      +  L+ + + V  ++ ++S+ +++++ 
Sbjct: 1454 DLEK--IQQENEKLKNAKTDSELNSSK-----RIEFLENQLENVNKQIEELSKAEANKIQ 1506

Query: 657  SEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQE 716
            +++   + E +   L   K+ELA  I NL++   +L   I+ LE +K D+  +++  + E
Sbjct: 1507 NQLDMKNKENE--QLQKEKQELAEKINNLQIILNELQIKIEILEKEKSDLDKQIEK-LNE 1563

Query: 717  NMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKS 776
            +++ ++   K    +I +L        +S + +Q      +Q    Y + I  EL +   
Sbjct: 1564 DLNNSESKNKEIERQIFQL-----QNRKSDVNSQLNT---LQVDKDYYQKIIDELHQKND 1615

Query: 777  RICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRV 836
                L + I V+ D+   L +  DQL    ++  K  +E    +D+L      L D ++ 
Sbjct: 1616 E---LVQRIKVLVDQLNELLKVKDQLNGSNEDLLKKITELQGLKDQLEENYLKLKDDNQT 1672

Query: 837  VEKQLLEIEHENKELQKKNQIL---LEENQNLQISLSDMQQHYNALVEKANRTDLAESES 893
            + +   +++  N+ L+++   L    E N++    +S+    Y ++    N  +L E ++
Sbjct: 1673 ISEMKEQLDDVNELLKERISELEGIQESNESKIEEISNELDKYKSMTTDLN--NLTEIDN 1730

Query: 894  TKYQ-TQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIE---SAIRDK-KVLNE 948
                 + +++   +L     E Q  I + ++  ++L+   +TQ++   S I+D    LN 
Sbjct: 1731 ISIDGSGIKERNDSLNEKIKELQDKIDELQRNYDELQ-SLHTQVKDENSRIKDSYNELNA 1789

Query: 949  KYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQ----KQQTQSP-DY 1003
              EK       L+   ++ +++++ LN +  +L + N +L D + Q    K + QS  D 
Sbjct: 1790 SKEKLQINFDNLDQNNKKLESDLDKLNKSFNDLLENNQQLQDNNNQLNEEKNKLQSDFDN 1849

Query: 1004 TEQYINEINKLNALLKQKDEEIIALNQKINNAQV-------SYMSMVSDYESKLAQFTTK 1056
            ++  I + N+    L + + ++   N+ +N  Q             V +   ++ +   +
Sbjct: 1850 SQNDIKKFNENINQLCESNNKLENANKDLNERQKILERDNNELKRQVENLMGEINKLNEE 1909

Query: 1057 LENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISS 1116
             EN++ E + +  +L+   Q+++E++ L    +D+I+ L   K   E N+   E  + S 
Sbjct: 1910 KENLDRERKSLEGELIKQNQNDDEIKRL----NDEIQSLNHHKKELEENLKLKENQL-SD 1964

Query: 1117 TIEPMSDDANNVDXXXXXXXXXXXXLKV-QEEEEFIQERSVLQEQSAKLNTELQECYTKI 1175
                +S  +N ++            LK  Q   E I++ + LQE+  KL  ++ +     
Sbjct: 1965 LSNTLSTISNALNSQISGLKEQIEELKQKQNPNELIEKLNELQEEKKKLEQDITDKDKLN 2024

Query: 1176 IQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDN 1212
             +L+    EL      + E+I QL  K   L   ND+
Sbjct: 2025 EELQKRVDELEKEKQNHYEEIQQLNLKTRDLELNNDD 2061



 Score =  154 bits (373), Expect = 2e-35
 Identities = 285/1391 (20%), Positives = 579/1391 (41%), Gaps = 103/1391 (7%)

Query: 234  DEKQRLLKDIESKDVRISSL-EEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXX 292
            D+  +L  D +S   +  SL +E +  +E AR E   E +K  + L              
Sbjct: 644  DKISKLESDKKSYQDKYESLSKELDYNIENARKEYE-EKTKDLRRLYDKNIQDLSDLQKG 702

Query: 293  XXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQT---NKELENKL 349
              + ++ +E   EEK   EE+      +  E+ + +  +  L  Q ++    N EL+ +L
Sbjct: 703  KQILERKLEE--EEKKHEEEREWERNKSQEEIKRGLNRIIELESQQKRIYIENDELKERL 760

Query: 350  ATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKIN--KNEI 407
             T+  +   VS   K     I ++   N   K+ +   Q   + LN      +N  KNE 
Sbjct: 761  QTVYID---VSEKFKNEFEFIKKQYEDNI--KVLNDRQQEEIDQLNLQNKNMLNVLKNEK 815

Query: 408  AKLEMVIQSLN---KDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPS 464
              ++  +       KDL DK  ++ ++             K           +Q+ +  +
Sbjct: 816  IIVQNQLNEARQRVKDLEDKNQILLDQKQTREDGIDRIEEKQREYEDKISSLEQNFDHLN 875

Query: 465  LIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANK 524
            L H     +   EI K++ + +Q +N  + D N     +K+      + + N EI+  N+
Sbjct: 876  LEHQKDMEKLQAEIKKLESEKQQLINKMMNDHNSNKDQKKMNEIISDLQKRNSEIEQKNQ 935

Query: 525  NMIKVKSNHKLKLKQMQKTIDNFS-KVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQL 583
                       ++ Q+++ ID    KV++ + E  ++ +E  ++ Q +++ E+EK  LQ 
Sbjct: 936  -----------EINQLKQEIDQEKEKVTNLDTEKSKMQKEKINMEQIISQNEQEKKELQQ 984

Query: 584  HLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDK 643
             + +Y+      +D     I+ +   +T    I  L S+  +  ++ +  ++K+    DK
Sbjct: 985  VITEYEQSL---NDFNINSIKQKEQIKTLQNQIQSLNSEISNFNEKENEEKEKHKNEIDK 1041

Query: 644  LAD-ISQLQSDQVCSEIKSVHLEEQIDALSAS-KKELALVIENL-KLDKEQLYGTIKDLE 700
            L   ++ LQ+ +     K +H  EQID  +   KKE+  +   + +L+KE+   TI+D +
Sbjct: 1042 LNQKLNDLQNQR-----KILH--EQIDLQNEHHKKEMNDIQSKINELEKEKKK-TIEDFQ 1093

Query: 701  NDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQER 760
            N  ++I  +    I++NMD  +   K    KI +L  + N+  Q K+  +   D    E 
Sbjct: 1094 NKIKNIQEESDRKIKQNMDEIESKNK----KIQDLEQERNN--QQKMIEKLAKDNS-DEY 1146

Query: 761  DLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQE 820
            +  +     +L   +    + E  IA +       +++ ++L   + E QK  SE   Q 
Sbjct: 1147 EEVVNLFNQQLDNLRQNNRQNENLIASLRSSNEEKQKEIEKLVQEISELQKQISEIKNQN 1206

Query: 821  DELVNRLA-VLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNL-QISLSDMQQHYNA 878
            D    RL     +  + +  ++ ++E + K LQ++ + L   N NL Q ++S  +     
Sbjct: 1207 DFETERLLNESKEAKQKMASKIKDLESDKKFLQQEIEKLKRINDNLNQQNMSQKRDFDEE 1266

Query: 879  LVEKANRTDLAESESTKYQTQLRDLE-SNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIE 937
            L +K+N+           Q Q+ + + S L    H  Q    ++K E++ L IE     +
Sbjct: 1267 LSQKSNKIKELNERIIDLQKQINNDDLSQLNSRLHNLQ----KQKDEVDQLNIELKN--D 1320

Query: 938  SAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQ 997
             +   K++ +   E+  E + Q    L +YK  + +L    E L + N++ ++  +  Q+
Sbjct: 1321 KSNLQKQISSLAKER--EDLKQQADSLNDYKKRVSDLEKEKENLVQ-NIKNMEIQISNQK 1377

Query: 998  TQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKL 1057
              +    +  I  + K    +K + E I   + K  N Q+  +    + E K+ +   K+
Sbjct: 1378 DGNQPKNDALITALQKQLESMKNRRENI-EKDLKAQNQQL--VDKNKELEEKVQELMHKI 1434

Query: 1058 ENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISST 1117
              +  E+ +   Q    +Q N +L+ + +E +    +LK  K   E+N  K    +  + 
Sbjct: 1435 TELNLELCKFKTQ---QRQLNRDLEKIQQENE----KLKNAKTDSELNSSKRIEFL-ENQ 1486

Query: 1118 IEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQ 1177
            +E ++     +             +K +E E+  +E+  L E+   L   L E   KI  
Sbjct: 1487 LENVNKQIEELSKAEANKIQNQLDMKNKENEQLQKEKQELAEKINNLQIILNELQIKIEI 1546

Query: 1178 LETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAE 1237
            LE   ++L        E +N  +SK +++  +   L +  +++ S +++    + +    
Sbjct: 1547 LEKEKSDLDKQIEKLNEDLNNSESKNKEIERQIFQLQNRKSDVNSQLNTLQVDKDYYQKI 1606

Query: 1238 LWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQN 1297
            + + H  Q+  +  +    L  QL+      +QL  S +   ++ T      +Q+     
Sbjct: 1607 IDELH--QKNDELVQRIKVLVDQLNELLKVKDQLNGSNEDLLKKITELQGLKDQLEENYL 1664

Query: 1298 KLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQ 1357
            KL+D  + +  ++E+  DV   ++   SE+E  + +                 ++  E  
Sbjct: 1665 KLKDDNQTISEMKEQLDDVNELLKERISELEGIQES-----------NESKIEEISNELD 1713

Query: 1358 SYKQMQEQ-----SILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTH---QL 1409
             YK M         I NI+ + + +K+ +            ++++ +    EL     Q+
Sbjct: 1714 KYKSMTTDLNNLTEIDNISIDGSGIKERNDSLNEKIKELQDKIDELQRNYDELQSLHTQV 1773

Query: 1410 ELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHEN 1469
            + ++S I    +E   +  +    F+N+ Q   + E  ++ L  +  ++L     ++ +N
Sbjct: 1774 KDENSRIKDSYNELNASKEKLQINFDNLDQNNKKLESDLDKLN-KSFNDLLENNQQLQDN 1832

Query: 1470 ANHY--ETMQKESEIERVKL-IEELNVKITESVSLNKQVAELNKALEEEVA----KTNEM 1522
             N    E  + +S+ +  +  I++ N  I +    N ++   NK L E         NE+
Sbjct: 1833 NNQLNEEKNKLQSDFDNSQNDIKKFNENINQLCESNNKLENANKDLNERQKILERDNNEL 1892

Query: 1523 QTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDE-QLDNTMNKELL 1581
            +  +EN   EI  LN+E  NL    ++   ++ K      + K+  DE Q  N   KEL 
Sbjct: 1893 KRQVENLMGEINKLNEEKENLDRERKSLEGELIKQNQNDDEIKRLNDEIQSLNHHKKELE 1952

Query: 1582 DAVPRAELDLA 1592
            + +   E  L+
Sbjct: 1953 ENLKLKENQLS 1963



 Score =  131 bits (316), Expect = 2e-28
 Identities = 193/882 (21%), Positives = 393/882 (44%), Gaps = 83/882 (9%)

Query: 143  DVTHLSNTIKEKDNALSVLQVK-----MKIMETTILDLQEKINEKDQI-IEAKNKATTXX 196
            +++  SN IKE +  +  LQ +     +  + + + +LQ++ +E DQ+ IE KN  +   
Sbjct: 1266 ELSQKSNKIKELNERIIDLQKQINNDDLSQLNSRLHNLQKQKDEVDQLNIELKNDKSNLQ 1325

Query: 197  XXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEA 256
                           ED KQQ   + + +    ++ + EK+ L+++I++ +++IS+ ++ 
Sbjct: 1326 KQISSLAKER-----EDLKQQADSLND-YKKRVSDLEKEKENLVQNIKNMEIQISNQKDG 1379

Query: 257  NKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSL 316
            N+    A        + L ++LE                 +Q ++    +  E+EEK   
Sbjct: 1380 NQPKNDALI------TALQKQLESMKNRRENIEKDLKAQNQQLVD----KNKELEEKVQE 1429

Query: 317  EIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSP--LISRKS 374
             +  +TEL   +EL +    Q RQ N++LE K+     + K   + S+  S   +   ++
Sbjct: 1430 LMHKITELN--LELCK-FKTQQRQLNRDLE-KIQQENEKLKNAKTDSELNSSKRIEFLEN 1485

Query: 375  GRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTX 434
                 +K     S+  +  +    D K  +NE  +L+   Q L + + + + +++E    
Sbjct: 1486 QLENVNKQIEELSKAEANKIQNQLDMKNKENE--QLQKEKQELAEKINNLQIILNELQIK 1543

Query: 435  XXXXXXXXXGKDTLIAQLQLEHQQHMEGPS------LIHVGTNTEDVNE---IAKVQEQL 485
                       D  I +L  E   + E  +      +  +     DVN      +V +  
Sbjct: 1544 IEILEKEKSDLDKQIEKLN-EDLNNSESKNKEIERQIFQLQNRKSDVNSQLNTLQVDKDY 1602

Query: 486  KQELNDEIKDVNVKDLIEKLKSAEEQITQL---NDEIDAANKNMIKVKSNHKLKLKQMQK 542
             Q++ DE+   N  +L++++K   +Q+ +L    D+++ +N++++K K      LK   +
Sbjct: 1603 YQKIIDELHQKN-DELVQRIKVLVDQLNELLKVKDQLNGSNEDLLK-KITELQGLKDQLE 1660

Query: 543  TIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKM 602
              +N+ K+ D N+ I  + E+L  +++ + E   E   +Q            E D YK M
Sbjct: 1661 --ENYLKLKDDNQTISEMKEQLDDVNELLKERISELEGIQESNESKIEEISNELDKYKSM 1718

Query: 603  I-EMENLAETRLKAI--SLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEI 659
              ++ NL E    +I  S ++ +   L +++  LQ K DE++    ++  L + QV  E 
Sbjct: 1719 TTDLNNLTEIDNISIDGSGIKERNDSLNEKIKELQDKIDELQRNYDELQSLHT-QVKDE- 1776

Query: 660  KSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMD 719
             +  +++  + L+ASK++L +  +NL  + ++L   +  L     D++   Q     N  
Sbjct: 1777 -NSRIKDSYNELNASKEKLQINFDNLDQNNKKLESDLDKLNKSFNDLLENNQQLQDNNNQ 1835

Query: 720  LTDKLEKM------SAEKISELLAKINH--EEQSKIQTQFGIDAKIQERDLYIENIESEL 771
            L ++  K+      S   I +    IN   E  +K++     +  + ER   +E   +EL
Sbjct: 1836 LNEEKNKLQSDFDNSQNDIKKFNENINQLCESNNKLE---NANKDLNERQKILERDNNEL 1892

Query: 772  SKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLM 831
               K ++  L   I  + + + +L+R+   L   L ++ +   E     DE+ +    L 
Sbjct: 1893 ---KRQVENLMGEINKLNEEKENLDRERKSLEGELIKQNQNDDEIKRLNDEIQS----LN 1945

Query: 832  DHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAES 891
             H + +E+ L   E++  +L   +  L   +  L   +S +++    L +K N  +L E 
Sbjct: 1946 HHKKELEENLKLKENQLSDL---SNTLSTISNALNSQISGLKEQIEELKQKQNPNELIE- 2001

Query: 892  ESTKYQTQLRDLESNL---KRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNE 948
            +  + Q + + LE ++    ++  E Q  + + +KE ++   E   Q+    RD + LN 
Sbjct: 2002 KLNELQEEKKKLEQDITDKDKLNEELQKRVDELEKEKQN-HYEEIQQLNLKTRDLE-LNN 2059

Query: 949  KYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNK--MNLEL 988
              E  IE V Q++ ++ ++KN IENLN  ++ L     NL+L
Sbjct: 2060 DDEDQIE-VVQIKQKIDDHKNEIENLNKLIDSLRNDISNLKL 2100



 Score =  122 bits (295), Expect = 6e-26
 Identities = 224/1190 (18%), Positives = 521/1190 (43%), Gaps = 120/1190 (10%)

Query: 477  EIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQI-----TQLNDEIDAANKNMIKVKS 531
            E+   Q+ + Q + + IK VN ++  ++     E +     ++L D+      ++ ++  
Sbjct: 330  EVIDEQKNILQSVINSIKQVNEQEFNKQKSQNHENVDNEAKSKLFDQKQQFVSSISQIME 389

Query: 532  NHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHL---VDY 588
              ++  K+  K   N + +  SN+EI R+  +   L++K+++LE++   L+      ++Y
Sbjct: 390  ELQVLYKEQHK---NNNMIRISNQEIERINLKEFDLNEKLSKLEQDLEMLREQRKIEIEY 446

Query: 589  DSGRM--IESD---VYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDK 643
            ++  +  IES+   +  +  E + L        S  E  K ++ + +  L+   D+    
Sbjct: 447  NNRAVEAIESEKASLRTRRNEFQKLLNDPATNDSDKELYKGEIEKLILQLKNLDDDKNAF 506

Query: 644  LADISQLQSDQ------VCSEIKSVHLE----EQIDA--LSASKKELALVIENLKLDKEQ 691
            +A+   L+ +       +  +I++   E    E IDA  +   + ++ L++EN     +Q
Sbjct: 507  IAENDDLKKEDGLEAKVIIQQIQTAQNEKNSFEAIDANNVEFHQNKIKLLVENQNKISDQ 566

Query: 692  LYGTIKDLENDKEDIMNKLQN----YIQENMDLTDKLEKMSAEKISELLAKINHEEQSKI 747
            +    K LE  K    + L+     +  EN  L DK+ +M  E ++  L+ I+ + Q+  
Sbjct: 567  ICLLRKQLEEQKYSYNSLLEEENKLFDLENAPL-DKIYEMEVEMLNNQLSMIDKQRQNLQ 625

Query: 748  QTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQ 807
                 ++ K  E    + +  S+L   K       ES++  ++  Y++E    +     +
Sbjct: 626  SELDSVNHKHYETTNMLNDKISKLESDKKSYQDKYESLS--KELDYNIENARKEYEEKTK 683

Query: 808  EKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQI 867
            + ++ Y +      +L     +L   +R +E++  + E E +  + K+Q  ++   N  I
Sbjct: 684  DLRRLYDKNIQDLSDLQKGKQIL---ERKLEEEEKKHEEEREWERNKSQEEIKRGLNRII 740

Query: 868  SLSDMQQHY----NALVEKANRT--DLAESESTKYQTQLRDLESNLK----RITHEHQTL 917
             L   Q+      + L E+      D++E    +++   +  E N+K    R   E   L
Sbjct: 741  ELESQQKRIYIENDELKERLQTVYIDVSEKFKNEFEFIKKQYEDNIKVLNDRQQEEIDQL 800

Query: 918  IVQKKKEIEDLEIE---FNTQIESA------IRDK-KVLNEKYEKNIEYVTQLEAQLQEY 967
             +Q K  +  L+ E      Q+  A      + DK ++L ++ +   + + ++E + +EY
Sbjct: 801  NLQNKNMLNVLKNEKIIVQNQLNEARQRVKDLEDKNQILLDQKQTREDGIDRIEEKQREY 860

Query: 968  KNNIENLNMNVEELN---KMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEE 1024
            ++ I +L  N + LN   + ++E +   ++K +++      + +N+ N      ++K  E
Sbjct: 861  EDKISSLEQNFDHLNLEHQKDMEKLQAEIKKLESEKQQLINKMMNDHNSNKD--QKKMNE 918

Query: 1025 IIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQIL 1084
            II+  QK N+        ++  + ++ Q   K+ N++ E  ++ K+ ++ +Q   + +  
Sbjct: 919  IISDLQKRNSEIEQKNQEINQLKQEIDQEKEKVTNLDTEKSKMQKEKINMEQIISQNEQE 978

Query: 1085 VREQDDQIKELKETKLTFEMNIPKTEGMI--ISSTIEPMSDDANNVDXXXXXXXXXXXXL 1142
             +E    I E +++   F +N  K +  I  + + I+ ++ + +N +             
Sbjct: 979  KKELQQVITEYEQSLNDFNINSIKQKEQIKTLQNQIQSLNSEISNFNE------------ 1026

Query: 1143 KVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSK 1202
              +E EE  + ++ + + + KLN +LQ       Q + L+ ++   +  +++++N ++SK
Sbjct: 1027 --KENEEKEKHKNEIDKLNQKLN-DLQN------QRKILHEQIDLQNEHHKKEMNDIQSK 1077

Query: 1203 LEQLNTEN----DNLLSTVAELRSSISSAVDQRGFEIAELWK--QHLAQREADFQKTEHE 1256
            + +L  E     ++  + +  ++      + Q   EI    K  Q L Q   + QK   +
Sbjct: 1078 INELEKEKKKTIEDFQNKIKNIQEESDRKIKQNMDEIESKNKKIQDLEQERNNQQKMIEK 1137

Query: 1257 LRVQLS-AFE---SKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEK 1312
            L    S  +E   + + Q LD+++ + ++  N I       SL++  ++K++ +  L ++
Sbjct: 1138 LAKDNSDEYEEVVNLFNQQLDNLRQNNRQNENLI------ASLRSSNEEKQKEIEKLVQE 1191

Query: 1313 YADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINE 1372
             +++  QI  ++++ + E                    DL ++ + + Q + + +  IN+
Sbjct: 1192 ISELQKQISEIKNQNDFETERLLNESKEAKQKMASKIKDLESD-KKFLQQEIEKLKRIND 1250

Query: 1373 E-NAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKD-SEIYQKTH---EYTITL 1427
              N Q                 ++ +   ++++L  Q+   D S++  + H   +    +
Sbjct: 1251 NLNQQNMSQKRDFDEELSQKSNKIKELNERIIDLQKQINNDDLSQLNSRLHNLQKQKDEV 1310

Query: 1428 TQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKL 1487
             Q N E +N +  L   +K+I  L  E+E +L      +++       ++KE E   V+ 
Sbjct: 1311 DQLNIELKNDKSNL---QKQISSLAKERE-DLKQQADSLNDYKKRVSDLEKEKE-NLVQN 1365

Query: 1488 IEELNVKITESVSLNKQ-----VAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEI-T 1541
            I+ + ++I+     N+      +  L K LE    +   ++  L+ Q  ++V  N E+  
Sbjct: 1366 IKNMEIQISNQKDGNQPKNDALITALQKQLESMKNRRENIEKDLKAQNQQLVDKNKELEE 1425

Query: 1542 NLQNMVRASSSKIQKHVSFASDTKQ-GRDEQLDNTMNKELLDAVPRAELD 1590
             +Q ++   +    +   F +  +Q  RD +     N++L +A   +EL+
Sbjct: 1426 KVQELMHKITELNLELCKFKTQQRQLNRDLEKIQQENEKLKNAKTDSELN 1475



 Score =  117 bits (281), Expect = 3e-24
 Identities = 218/1184 (18%), Positives = 512/1184 (43%), Gaps = 125/1184 (10%)

Query: 483  EQLKQELNDEIKDVNVKDLIEKLKSAEE------QITQLNDEIDAANKNMIKVKSNHKL- 535
            E +K+E  +++K++     +E  K AEE      +I    DE++  ++ M ++ S  +  
Sbjct: 184  ETIKKEHEEKLKEIESDTKLEADKIAEERKAKQKEIDLKTDELERVDRTMREIDSKRRRS 243

Query: 536  -KLKQMQKT-IDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRM 593
              L ++ K+ +   S   DS K+     E  ++   K   LE++K N++         + 
Sbjct: 244  ESLARLYKSKVSLLSDELDSQKKCFNEVEGRNNTIMKEI-LEQKKENIR---QSEKLQQK 299

Query: 594  IESDV--YKKMIEMENLAETR-----LKAISLLESQKFDLVQELHILQQKYDEVEDKLAD 646
              +D+  ++K+++ E L           A+ +++ QK  L   ++ ++Q  ++  +K   
Sbjct: 300  FNNDLFNFQKILDNERLQHNNDINSLNNALEVIDEQKNILQSVINSIKQVNEQEFNKQKS 359

Query: 647  ISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLE--NDKE 704
             +    D           ++ + ++S   +EL ++ +    +   +  + +++E  N KE
Sbjct: 360  QNHENVDNEAKSKLFDQKQQFVSSISQIMEELQVLYKEQHKNNNMIRISNQEIERINLKE 419

Query: 705  DIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYI 764
              +N+  + +++++++  +  K+  E  +  +  I  E+ S ++T+     K+   D   
Sbjct: 420  FDLNEKLSKLEQDLEMLREQRKIEIEYNNRAVEAIESEKAS-LRTRRNEFQKLL-NDPAT 477

Query: 765  ENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELV 824
             + + EL  YK  I +L     +++     L+   D   +++ E      E  ++   ++
Sbjct: 478  NDSDKEL--YKGEIEKL-----ILQ-----LKNLDDDKNAFIAENDDLKKEDGLEAKVII 525

Query: 825  NRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQN--------LQISLSDMQQHY 876
             ++    +     E     I+  N E  +    LL ENQN        L+  L + +  Y
Sbjct: 526  QQIQTAQNEKNSFE----AIDANNVEFHQNKIKLLVENQNKISDQICLLRKQLEEQKYSY 581

Query: 877  NALVEKANRT-DLAESESTK-YQTQLRDLESNLKRITHEHQTLIVQ----KKKEIEDLEI 930
            N+L+E+ N+  DL  +   K Y+ ++  L + L  I  + Q L  +      K  E   +
Sbjct: 582  NSLLEEENKLFDLENAPLDKIYEMEVEMLNNQLSMIDKQRQNLQSELDSVNHKHYETTNM 641

Query: 931  EFNTQIESAIRDKKVLNEKYE---KNIEYVTQLEAQLQEYKNNIENL----NMNVEELNK 983
              N +I     DKK   +KYE   K ++Y   +E   +EY+   ++L    + N+++L+ 
Sbjct: 642  -LNDKISKLESDKKSYQDKYESLSKELDY--NIENARKEYEEKTKDLRRLYDKNIQDLSD 698

Query: 984  M--NLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMS 1041
            +    +++++ +++++ +  +  E    E NK    +K+    II L  +     +    
Sbjct: 699  LQKGKQILERKLEEEEKKHEEEREW---ERNKSQEEIKRGLNRIIELESQQKRIYIENDE 755

Query: 1042 MVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLT 1101
            +    ++     + K +N  E ++         KQ+ + +++L   Q ++I +L      
Sbjct: 756  LKERLQTVYIDVSEKFKNEFEFIK---------KQYEDNIKVLNDRQQEEIDQLNLQNKN 806

Query: 1102 FEMNIPKTEGMIISSTIEPMS------DDANNVDXXXXXXXXXXXXLKVQEEEEFIQERS 1155
              +N+ K E +I+ + +          +D N +                +++ E+  + S
Sbjct: 807  M-LNVLKNEKIIVQNQLNEARQRVKDLEDKNQILLDQKQTREDGIDRIEEKQREYEDKIS 865

Query: 1156 VLQEQSAKLNTE----LQECYTKIIQLET-----LNTELTGHDV-VNQEQINQLKSKLEQ 1205
             L++    LN E    +++   +I +LE+     +N  +  H+   +Q+++N++ S L++
Sbjct: 866  SLEQNFDHLNLEHQKDMEKLQAEIKKLESEKQQLINKMMNDHNSNKDQKKMNEIISDLQK 925

Query: 1206 LNTENDNLLSTVAELRSSI---SSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLS 1262
             N+E +     + +L+  I      V     E +++ K+ +   E    + E E + +L 
Sbjct: 926  RNSEIEQKNQEINQLKQEIDQEKEKVTNLDTEKSKMQKEKI-NMEQIISQNEQE-KKELQ 983

Query: 1263 AFESKYEQLLDSVQSSTQEETNKIVTME-QVTSLQNKLQDKEEHLRNLQEKYADVINQIE 1321
               ++YEQ L+    ++ ++  +I T++ Q+ SL +++ +  E     +EK+ + I+++ 
Sbjct: 984  QVITEYEQSLNDFNINSIKQKEQIKTLQNQIQSLNSEISNFNEKENEEKEKHKNEIDKLN 1043

Query: 1322 ILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTE-NQSYKQMQ------EQSILNINEEN 1374
               +++++++                   D++++ N+  K+ +      +  I NI EE+
Sbjct: 1044 QKLNDLQNQRKILHEQIDLQNEHHKKEMNDIQSKINELEKEKKKTIEDFQNKIKNIQEES 1103

Query: 1375 AQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEF 1434
             +  K +            ++ D E    E  +Q ++ +      + EY   +   N + 
Sbjct: 1104 DRKIKQN---MDEIESKNKKIQDLEQ---ERNNQQKMIEKLAKDNSDEYEEVVNLFNQQL 1157

Query: 1435 ENVRQQLVEYEKRIEDL---TYEKESELAILRLKMHENANHYETMQKESEIERVKLIEEL 1491
            +N+RQ   + E  I  L     EK+ E+  L  ++ E       ++ +++ E  +L+ E 
Sbjct: 1158 DNLRQNNRQNENLIASLRSSNEEKQKEIEKLVQEISELQKQISEIKNQNDFETERLLNES 1217

Query: 1492 NVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEI-EIVTLNDEITNLQNMVRAS 1550
                 +  S  K +    K L++E+ K   +   L  Q + +    ++E++   N ++  
Sbjct: 1218 KEAKQKMASKIKDLESDKKFLQQEIEKLKRINDNLNQQNMSQKRDFDEELSQKSNKIKEL 1277

Query: 1551 SSKI---QKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDL 1591
            + +I   QK ++  +D     + +L N   ++  D V +  ++L
Sbjct: 1278 NERIIDLQKQIN--NDDLSQLNSRLHNLQKQK--DEVDQLNIEL 1317



 Score = 39.1 bits (87), Expect = 0.99
 Identities = 61/327 (18%), Positives = 125/327 (38%), Gaps = 20/327 (6%)

Query: 220  KMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELE 279
            K+Q NF  ++       ++L  D++  +   + L E N+ L+    +++ E +KL  + +
Sbjct: 1793 KLQINFDNLD----QNNKKLESDLDKLNKSFNDLLENNQQLQDNNNQLNEEKNKLQSDFD 1848

Query: 280  QXXXXXXXXXXXXXXLAK-----QSIEPSCEEKTEIEEKGSLEIANMTE-LTKKIELLEH 333
                           L +     ++      E+ +I E+ + E+    E L  +I  L  
Sbjct: 1849 NSQNDIKKFNENINQLCESNNKLENANKDLNERQKILERDNNELKRQVENLMGEINKLNE 1908

Query: 334  LNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSET 393
                + +  K LE +L         +   + +   L   K       K+K   +QLS  +
Sbjct: 1909 EKENLDRERKSLEGELIKQNQNDDEIKRLNDEIQSLNHHKKELEENLKLKE--NQLSDLS 1966

Query: 394  LNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYV--ISEKDTXXXXXXXXXXGKDTLIAQ 451
                T      ++I+ L+  I+ L +     E +  ++E              KD L  +
Sbjct: 1967 NTLSTISNALNSQISGLKEQIEELKQKQNPNELIEKLNELQEEKKKLEQDITDKDKLNEE 2026

Query: 452  LQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQ 511
            LQ +    +E     H     E++ ++      L+   ND+   + V  + +K+   + +
Sbjct: 2027 LQ-KRVDELEKEKQNHY----EEIQQLNLKTRDLELN-NDDEDQIEVVQIKQKIDDHKNE 2080

Query: 512  ITQLNDEIDAANKNMIKVKSNHKLKLK 538
            I  LN  ID+   ++  +K  +  K K
Sbjct: 2081 IENLNKLIDSLRNDISNLKLENSRKAK 2107


>UniRef50_UPI00006CF26E Cluster: Viral A-type inclusion protein repeat
            containing protein; n=1; Tetrahymena thermophila
            SB210|Rep: Viral A-type inclusion protein repeat
            containing protein - Tetrahymena thermophila SB210
          Length = 2519

 Score =  172 bits (419), Expect = 6e-41
 Identities = 294/1457 (20%), Positives = 638/1457 (43%), Gaps = 125/1457 (8%)

Query: 140  QLGDVTHLSNTIKEKDNALSVLQVKMKIM--------ETTILDLQEKINEKDQIIEAKNK 191
            +L D   + + I E++  LS    +MK+M        E T+  L++ I EK  + +  N+
Sbjct: 666  KLNDQERMIDQIVEENQMLSKELEQMKLMQEFKQAQHEETVHQLKKLIAEKSNVTDEMNQ 725

Query: 192  ATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRIS 251
                                    ++  + ++    M  E K   ++ LK +E  +   +
Sbjct: 726  ELRLRNIDLVEQIKQLQQQNLLLNERSKESEKQRQDMAEEKKQAHEKYLKYLEKYNEETT 785

Query: 252  SLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIE 311
             L+ + + L +   E   E+ ++  E+ Q               AKQ ++ S +++ E +
Sbjct: 786  HLQASIQELTSNFNEKEFENLRIKDEVIQGNERIRELESNISQ-AKQ-VQDSLQQEIE-Q 842

Query: 312  EKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLIS 371
            +K  +E     +L +++  LE  + Q +   +E+E    T+      +    K+ + L++
Sbjct: 843  KKNQIE-----QLEEQLIELEEADNQRKDLQEEIETLNETLNFRENELEEMKKQKTQLLN 897

Query: 372  RKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEK 431
            +      A        Q     + ++ + + N+     LE  ++ + K  ++ E V+ E+
Sbjct: 898  QIQELQAAKVQIEELVQTLKMRI-EELESQNNEQNNKLLEEKVEEVKK--LEDEKVVIEQ 954

Query: 432  DTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELND 491
            +             D ++ Q +LE  + +E   +       + +NEI+  +E++ Q L  
Sbjct: 955  ELNEIRKTKEA---DNIVIQNKLEQIKSLEQEKVFV----QQKINEISDEKERITQVLEG 1007

Query: 492  EIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQ----KTIDNF 547
            EIK +  K L+E  ++ +E I Q   EI+     + ++KS+ + +++       K  +NF
Sbjct: 1008 EIKILKEKLLLEDDQN-QEVINQKQTEIEQLRSQVQQLKSSIQKEIESFNNEKTKLEENF 1066

Query: 548  SKVSDSNKEIVR--LTEELHHLSQKVA-ELEE--EKGNLQLHLVDYDSGRMIESDVYKKM 602
             K         +  L E+   L Q  + ELE+  E    ++  ++ +  ++I+    +  
Sbjct: 1067 KKEKQETLLQCKRDLQEQCEQLQQNFSIELEKQIEIREKKIAKLEEEKSKVIQQSQEETQ 1126

Query: 603  IEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSD-QVCSEIKS 661
             E+E L E   + + L+  QK   +Q+  I+++  +E++  L +  QL    Q+  +   
Sbjct: 1127 QELETLKEDLERQVVLITEQKDQEIQQ--IIEKNSEELQGLLNEKQQLLKQIQLNKDEIQ 1184

Query: 662  VHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLT 721
            +H +  I A     +EL    E+  ++KE LY    +  N  ++  +KL++   E+  L 
Sbjct: 1185 MH-QNSIQAYEQQIQEL----ESSLIEKEGLY---IEKNNAFKEQQSKLRHLESESSQLK 1236

Query: 722  DKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYI-ENIESELSKYKSRICR 780
            ++ +++  +K S+L   +  + Q+  + +  ++ K+Q   LY  E I  + +  K    R
Sbjct: 1237 EEAQELK-DKASQLAESLEGQTQAYSKAKAEVE-KLQNEILYQQEKILQQENTIKILKER 1294

Query: 781  LEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELV----NRLAVL-MDHDR 835
             +E  +  E   Y LE K  QL        K  ++   + DE +    N +A L ++  +
Sbjct: 1295 QQEESSQSEKYVYELEDKVRQLEQEKASMVKLNNQLQQESDEKLLDKENEIAHLNLEKKQ 1354

Query: 836  VVEKQLLEIEHENKELQKKNQILLEENQ---NLQIS-LSDMQQHYNALVEKANRTDLAES 891
            +++ +L EIE   K  Q+   I L++ +   N +I  L ++ Q   A+ EK       E 
Sbjct: 1355 ILDSKLQEIEEIVKLQQQDKDISLQKQELIFNERIKELEELVQQ--AISEKEIIITQYED 1412

Query: 892  ESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYE 951
            ++ + + ++ DL   LK+I  + Q  I  + +EI+ L  +     +   + +K   E YE
Sbjct: 1413 KNNEKENKISDL---LKQIEEQSQN-IQNQNEEIDSLNQQVILLRQKISQKEKEKQENYE 1468

Query: 952  KNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEI 1011
            +  +    L   +++Y    +NL +++E    +  + +++ ++  Q Q  +  E + ++I
Sbjct: 1469 RESKEKQDL---IEKYAEEKQNLQISLENRFSVKQKQMEEQIKSYQEQLSNEQEAHQSQI 1525

Query: 1012 NKLNALLKQKDEEIIALNQKINNAQVSYMSMVSD----YESKLAQ---FTTKLENMEEEM 1064
             +   ++++    I  L  +I   +      +S+    YE++  +      ++EN+++E+
Sbjct: 1526 EQKEMIIEEHQNIIDELKTEIEGLKTQRYEKLSEQEQLYENQQQENRLLVKQIENLKKEI 1585

Query: 1065 QRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDD 1124
               S+QL+  ++  +E Q   ++ D QIK+++E K + E+N  + E      T E    +
Sbjct: 1586 VNKSEQLIAEREEQQETQ---QQFDMQIKQIEE-KSSQEINKIQQESQEAIETAEKQILE 1641

Query: 1125 ANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTE 1184
                             +  Q+EEE  Q   ++++   +L   LQE    + +   L  +
Sbjct: 1642 LKR----------QLEKIIKQKEEELQQANKLVEQVKEQL---LQEKNQSVKENNNLIQK 1688

Query: 1185 LTGHDVVNQEQINQLKSKLEQL--NTENDNLL--STVAELRSSISSAVDQRGFEIAELWK 1240
            +     +   ++N+LK + +Q+    EN+ L+   T A L+  I+    Q      +L +
Sbjct: 1689 IEQQQQLQLRELNELKEQNKQILAEAENNQLVFNQTEANLQEQIAYLKQQLDISNNKLEE 1748

Query: 1241 QH--LAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNK 1298
            +H    Q+  + QK E E   Q     +  E L D    + +E+      M  ++  +N+
Sbjct: 1749 EHNKFLQKFTNLQK-EAEQNTQKQVLLN--EALRDEKWKAEKEQILHSHKMT-ISQKENE 1804

Query: 1299 LQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQS 1358
            L +K + L  ++++  +  +     ++++++ + +                  + TE  S
Sbjct: 1805 LFEKNQELLQMKQQLEEFKSLSHTYQTKLKEIQESNEKQSVINTQIFTKQLDQVNTEKNS 1864

Query: 1359 YKQMQEQSILNINEENAQLKKS--SXXXXXXXXXXXXRVN-DAEAKVLELTHQLELKDSE 1415
             KQ  E     + E+  + +K                ++N + E K+++L+  ++ +D+ 
Sbjct: 1865 LKQNLENLNAKLQEKAEETQKLIVQNGEYLTKAHQLEQLNQEKETKIIQLSKNIQQQDTY 1924

Query: 1416 IYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYET 1475
            I QKT +    + Q+ D  + + +   EY K I+    + + +++  + ++ + +     
Sbjct: 1925 I-QKTAQ---EIQQKKDIIQTLNE---EYSKVIQQ-NEQLKHQISETQTQLEKQS----I 1972

Query: 1476 MQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEE--VAKTNEMQTALENQEIEI 1533
            + K+ E+ER++L+ +  ++  E    NK   ELNK  EE   + +  E Q   ++ EIE 
Sbjct: 1973 IHKQKEVERLELVHKSKLEELE----NKHNEELNKIFEERRIMLEQLEEQKQQKDSEIEE 2028

Query: 1534 VTLN--DEITNLQNMVR 1548
            + L   +EI N + + +
Sbjct: 2029 LCLKYAEEIDNFKKLTK 2045



 Score =  165 bits (402), Expect = 7e-39
 Identities = 268/1411 (18%), Positives = 609/1411 (43%), Gaps = 120/1411 (8%)

Query: 144  VTHLSNTIKEKDNALSVLQVK-MKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXX 202
            +  L +   E++N L   +V+ +K +E   + +++++NE  +  EA N            
Sbjct: 920  IEELESQNNEQNNKLLEEKVEEVKKLEDEKVVIEQELNEIRKTKEADNIVIQNKLEQIKS 979

Query: 203  XXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLL-KDIESKDV---RISSLEEANK 258
                     +   +   + +     +E E K  K++LL +D ++++V   + + +E+   
Sbjct: 980  LEQEKVFVQQKINEISDEKERITQVLEGEIKILKEKLLLEDDQNQEVINQKQTEIEQLRS 1039

Query: 259  LLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEI 318
             ++  +  I  E      E  +                K+ ++  CE+   +++  S+E+
Sbjct: 1040 QVQQLKSSIQKEIESFNNEKTKLEENFKKEKQETLLQCKRDLQEQCEQ---LQQNFSIEL 1096

Query: 319  ANMTELT-KKIELLEHLNCQ-IRQTNKELENKLATM--GTESKAVSSPSKKGSPL--ISR 372
                E+  KKI  LE    + I+Q+ +E + +L T+    E + V    +K   +  I  
Sbjct: 1097 EKQIEIREKKIAKLEEEKSKVIQQSQEETQQELETLKEDLERQVVLITEQKDQEIQQIIE 1156

Query: 373  KSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKD 432
            K+       +      L    LN+D + ++++N I   E  IQ L   L++KE +  EK+
Sbjct: 1157 KNSEELQGLLNEKQQLLKQIQLNKD-EIQMHQNSIQAYEQQIQELESSLIEKEGLYIEKN 1215

Query: 433  TXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLI--HVGTNTEDVNEIAKVQEQLKQE-L 489
                         ++  +QL+ E Q+  +  S +   +   T+  ++     E+L+ E L
Sbjct: 1216 NAFKEQQSKLRHLESESSQLKEEAQELKDKASQLAESLEGQTQAYSKAKAEVEKLQNEIL 1275

Query: 490  NDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFS- 548
              + K +  ++ I+ LK  +++ +  +++     ++ ++     K  + ++   +   S 
Sbjct: 1276 YQQEKILQQENTIKILKERQQEESSQSEKYVYELEDKVRQLEQEKASMVKLNNQLQQESD 1335

Query: 549  -KVSDSNKEIVRLT-EELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMI-EM 605
             K+ D   EI  L  E+   L  K+ E+EE    ++L   D D     +  ++ + I E+
Sbjct: 1336 EKLLDKENEIAHLNLEKKQILDSKLQEIEE---IVKLQQQDKDISLQKQELIFNERIKEL 1392

Query: 606  ENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLE 665
            E L +  +    ++ +Q           + K +E E+K++D+ + Q ++    I++ +  
Sbjct: 1393 EELVQQAISEKEIIITQ----------YEDKNNEKENKISDLLK-QIEEQSQNIQNQN-- 1439

Query: 666  EQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLE 725
            E+ID+L+     L   I   + +K++ Y      E + ++  + ++ Y +E  +L   LE
Sbjct: 1440 EEIDSLNQQVILLRQKISQKEKEKQENY------ERESKEKQDLIEKYAEEKQNLQISLE 1493

Query: 726  KMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESI 785
               + K  ++  +I   ++     Q    ++I+++++ IE       ++++ I  L+  I
Sbjct: 1494 NRFSVKQKQMEEQIKSYQEQLSNEQEAHQSQIEQKEMIIE-------EHQNIIDELKTEI 1546

Query: 786  AVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIE 845
              ++ +RY    + +QL             Y  Q+ E  NRL V     + +E    EI 
Sbjct: 1547 EGLKTQRYEKLSEQEQL-------------YENQQQE--NRLLV-----KQIENLKKEIV 1586

Query: 846  HENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLES 905
            +++++L  + +   E  Q   + +  +++  +  + K  +      E+   + Q+ +L+ 
Sbjct: 1587 NKSEQLIAEREEQQETQQQFDMQIKQIEEKSSQEINKIQQESQEAIETA--EKQILELKR 1644

Query: 906  NLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEK----NIEYVTQLE 961
             L++I  + +  + Q  K +E ++ +   +   ++++   L +K E+     +  + +L+
Sbjct: 1645 QLEKIIKQKEEELQQANKLVEQVKEQLLQEKNQSVKENNNLIQKIEQQQQLQLRELNELK 1704

Query: 962  AQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINE-INKLNALLKQ 1020
             Q ++     EN N  V    + NL+    ++++Q   S +  E+  N+ + K   L  Q
Sbjct: 1705 EQNKQILAEAEN-NQLVFNQTEANLQEQIAYLKQQLDISNNKLEEEHNKFLQKFTNL--Q 1761

Query: 1021 KDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEE 1080
            K+ E     Q + N  +      ++ E  L      +   E E+   +++LL  KQ  EE
Sbjct: 1762 KEAEQNTQKQVLLNEALRDEKWKAEKEQILHSHKMTISQKENELFEKNQELLQMKQQLEE 1821

Query: 1081 LQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXX 1140
             + L      ++KE++E+    + ++  T+  I +  ++ ++ + N++            
Sbjct: 1822 FKSLSHTYQTKLKEIQES--NEKQSVINTQ--IFTKQLDQVNTEKNSLKQNLENLNAKLQ 1877

Query: 1141 XLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLK 1200
              K +E ++ I +      ++ +L    QE  TKIIQL     +   +     ++I Q K
Sbjct: 1878 E-KAEETQKLIVQNGEYLTKAHQLEQLNQEKETKIIQLSKNIQQQDTYIQKTAQEIQQKK 1936

Query: 1201 SKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQ 1260
              ++ LN E   ++    +L+  IS    Q       L KQ +  ++ + ++ E   + +
Sbjct: 1937 DIIQTLNEEYSKVIQQNEQLKHQISETQTQ-------LEKQSIIHKQKEVERLELVHKSK 1989

Query: 1261 LSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQI 1320
            L   E+K+ + L+ +     EE  + + +EQ   L+ + Q K+  +  L  KYA+ I+  
Sbjct: 1990 LEELENKHNEELNKI----FEE--RRIMLEQ---LEEQKQQKDSEIEELCLKYAEEIDNF 2040

Query: 1321 EILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQS--------YKQMQEQSILNINE 1372
            + L   ++++                     L    Q         Y Q + + ++ +N+
Sbjct: 2041 KKLTKNLQNQNEFLEKENAEKEELCNQFQVALNEFKQELNKRDELLYIQEEYEKLVEVNK 2100

Query: 1373 --ENAQLKKSSXXXXXXXXXXXXRVNDAEAKVL--ELTHQLELKDSEI---YQKTHEYTI 1425
              EN   KK+             + +  E K +  +   +++++ +E+   Y++T  +  
Sbjct: 2101 ILENDLEKKTKMIEESKVNLIQAKRDMQEMKKILDQKNKEIDVQKNELKEFYERTQVFAQ 2160

Query: 1426 TLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERV 1485
            T  +   E ++   +L++   +I     E+  ++  L++++ + A   E  Q   EI ++
Sbjct: 2161 TRDKDVKEVKDQYCKLLDEHNKIMSQYNEQSEKMDKLKVEISDYAK--EKAQINQEIRKL 2218

Query: 1486 KLIE-ELNVKITESVSLNKQVAELNKALEEE 1515
            +  E +L  ++ + + +NK++ E NK LEE+
Sbjct: 2219 QSNEKKLKQQLNDMIEVNKRLNEDNKKLEED 2249



 Score =  132 bits (318), Expect = 1e-28
 Identities = 228/1190 (19%), Positives = 510/1190 (42%), Gaps = 95/1190 (7%)

Query: 449  IAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSA 508
            + Q  LE  Q +E     ++G   + +  + K  E+ +Q       +   + +I+  ++ 
Sbjct: 465  LCQHYLEQAQELELKMNYNMGKTKDQLMHLMKYVEKFQQN------EYQYRSIIKLQRAK 518

Query: 509  EEQITQLNDEIDAANKNMIK--VKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHH 566
             E++     E+   NK + K  V+       ++ QK ++N  ++ ++     +L +E   
Sbjct: 519  IERV-----ELMLKNKQLTKEQVQEFFNEDREKTQKELNNLRELLENQMYCAKLLDENVE 573

Query: 567  LSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDL 626
            L Q+V +++E   ++   L +  +  +++S   K    +E     +     L ES+K   
Sbjct: 574  LQQQVEKIQEPGRSIFQQLTN--NVDVLKSIQNKLEQNIEQRVRLQKVVEDLEESKKNAS 631

Query: 627  VQELHILQQKYDEVE-DKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENL 685
                  L+ +  ++E +  + +  L S+ +  + K    E  ID +    + L+  +E +
Sbjct: 632  PDRSKKLEFQLTQIEKEHKSAVENLNSELLTQKQKLNDQERMIDQIVEENQMLSKELEQM 691

Query: 686  KLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINH-EEQ 744
            KL +E      K  ++  E+ +++L+  I E  ++TD++ +    +  +L+ +I   ++Q
Sbjct: 692  KLMQE-----FKQAQH--EETVHQLKKLIAEKSNVTDEMNQELRLRNIDLVEQIKQLQQQ 744

Query: 745  SKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGS 804
            + +  +   +++ Q +D+  E  ++   KY   + +  E           L+    +L S
Sbjct: 745  NLLLNERSKESEKQRQDMAEEKKQAH-EKYLKYLEKYNEETT-------HLQASIQELTS 796

Query: 805  YLQEKQ---KAYSEYTIQEDELVNRLAVLMDHDRVVEKQLL-EIEHENKELQKKNQILLE 860
               EK+       +  IQ +E +  L   +   + V+  L  EIE +  ++++  + L+E
Sbjct: 797  NFNEKEFENLRIKDEVIQGNERIRELESNISQAKQVQDSLQQEIEQKKNQIEQLEEQLIE 856

Query: 861  ENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQ 920
              +       D+Q+    L E  N  +    E  K +TQL +    L+    + + L+  
Sbjct: 857  LEE-ADNQRKDLQEEIETLNETLNFRENELEEMKKQKTQLLNQIQELQAAKVQIEELVQT 915

Query: 921  KKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEE 980
             K  IE+LE + N Q    + +K    E+ +K  +    +E +L E +   E  N+ ++ 
Sbjct: 916  LKMRIEELESQNNEQNNKLLEEKV---EEVKKLEDEKVVIEQELNEIRKTKEADNIVIQ- 971

Query: 981  LNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDE-EIIALNQKINNAQVSY 1039
             NK  LE I     K   Q   + +Q INEI+     + Q  E EI  L +K+       
Sbjct: 972  -NK--LEQI-----KSLEQEKVFVQQKINEISDEKERITQVLEGEIKILKEKLLLEDDQN 1023

Query: 1040 MSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETK 1099
              +++  ++++ Q  ++++ ++  +Q+  +       +NE+ ++    +++  KE +ET 
Sbjct: 1024 QEVINQKQTEIEQLRSQVQQLKSSIQKEIESF-----NNEKTKL----EENFKKEKQETL 1074

Query: 1100 LTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQE 1159
            L  + ++ +    +  +    +       +            +  Q +EE  QE   L+E
Sbjct: 1075 LQCKRDLQEQCEQLQQNFSIELEKQIEIREKKIAKLEEEKSKVIQQSQEETQQELETLKE 1134

Query: 1160 QSAKLNTELQECYTKIIQ--LETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTV 1217
               +    + E   + IQ  +E  + EL G     Q+ + Q++   +++    +++ +  
Sbjct: 1135 DLERQVVLITEQKDQEIQQIIEKNSEELQGLLNEKQQLLKQIQLNKDEIQMHQNSIQAYE 1194

Query: 1218 AELRSSISSAVDQRGFEIAE--LWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSV 1275
             +++   SS +++ G  I +   +K+  ++     +    +L+ +    + K  QL +S+
Sbjct: 1195 QQIQELESSLIEKEGLYIEKNNAFKEQQSKLR-HLESESSQLKEEAQELKDKASQLAESL 1253

Query: 1276 QSSTQEETNKIVTME----QVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEK 1331
            +  TQ  +     +E    ++   Q K+  +E  ++ L+E+  +  +Q E    E+ED+ 
Sbjct: 1254 EGQTQAYSKAKAEVEKLQNEILYQQEKILQQENTIKILKERQQEESSQSEKYVYELEDK- 1312

Query: 1332 VAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXX 1391
                                L+ E+      +E  I ++N E  Q+  S           
Sbjct: 1313 ---VRQLEQEKASMVKLNNQLQQESDEKLLDKENEIAHLNLEKKQILDSKLQEIEEIVKL 1369

Query: 1392 XXRVNDAEAKVLELTHQLELKDSE--IYQKTHEYTITLTQ---RNDEFEN----VRQQLV 1442
              +  D   +  EL     +K+ E  + Q   E  I +TQ   +N+E EN    + +Q+ 
Sbjct: 1370 QQQDKDISLQKQELIFNERIKELEELVQQAISEKEIIITQYEDKNNEKENKISDLLKQIE 1429

Query: 1443 EYEKRIEDLTYEKES---ELAILRLKM----HENANHYETMQKESEIERVKLIEE---LN 1492
            E  + I++   E +S   ++ +LR K+     E   +YE   KE +    K  EE   L 
Sbjct: 1430 EQSQNIQNQNEEIDSLNQQVILLRQKISQKEKEKQENYERESKEKQDLIEKYAEEKQNLQ 1489

Query: 1493 VKITESVSL-NKQVAELNKALEEEVAKTNEM-QTALENQEIEIVTLNDEITNLQNMVRAS 1550
            + +    S+  KQ+ E  K+ +E+++   E  Q+ +E +E+ I    + I  L+  +   
Sbjct: 1490 ISLENRFSVKQKQMEEQIKSYQEQLSNEQEAHQSQIEQKEMIIEEHQNIIDELKTEI--E 1547

Query: 1551 SSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDLAMYMLHQRD 1600
              K Q++   +   +   ++Q +N +  + ++ + +  ++ +  ++ +R+
Sbjct: 1548 GLKTQRYEKLSEQEQLYENQQQENRLLVKQIENLKKEIVNKSEQLIAERE 1597



 Score =  124 bits (300), Expect = 2e-26
 Identities = 216/1108 (19%), Positives = 490/1108 (44%), Gaps = 119/1108 (10%)

Query: 153  EKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXE 212
            +K+N ++ L ++ K     ILD   K+ E ++I++ + +                    E
Sbjct: 1340 DKENEIAHLNLEKK----QILD--SKLQEIEEIVKLQQQDKDISLQKQELIFNERIKELE 1393

Query: 213  DTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESK-DVRISSLEEANKLLEAARFEISLEH 271
            +  QQ    +E  I    +  +EK+  + D+  + + +  +++  N+ +++   ++ L  
Sbjct: 1394 ELVQQAISEKEIIITQYEDKNNEKENKISDLLKQIEEQSQNIQNQNEEIDSLNQQVILLR 1453

Query: 272  SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELL 331
             K++Q+ ++                +++ E   +EK ++ EK + E  N+     +I L 
Sbjct: 1454 QKISQKEKEK---------------QENYERESKEKQDLIEKYAEEKQNL-----QISLE 1493

Query: 332  EHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSS 391
               + + +Q  +++++    +  E +A  S  ++   +I     +N   ++K+    L +
Sbjct: 1494 NRFSVKQKQMEEQIKSYQEQLSNEQEAHQSQIEQKEMIIEEH--QNIIDELKTEIEGLKT 1551

Query: 392  ---ETLNQDTDKKINKNEIAKLEMV-IQSLNKDLVDK-EYVISEKDTXXXXXXXXXXGKD 446
               E L++      N+ +  +L +  I++L K++V+K E +I+E++             D
Sbjct: 1552 QRYEKLSEQEQLYENQQQENRLLVKQIENLKKEIVNKSEQLIAEREEQQETQQQF----D 1607

Query: 447  TLIAQLQLEHQQHM---EGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIE 503
              I Q++ +  Q +   +  S   + T  + + E+ +  E++ ++  +E++  N   L+E
Sbjct: 1608 MQIKQIEEKSSQEINKIQQESQEAIETAEKQILELKRQLEKIIKQKEEELQQAN--KLVE 1665

Query: 504  KLKSAEEQITQLNDEIDAANKNMI-KVKSNHKLKLKQMQKTIDNFSKV---SDSNKEIVR 559
            ++K   EQ+ Q  ++    N N+I K++   +L+L+++ +  +   ++   +++N+ +  
Sbjct: 1666 QVK---EQLLQEKNQSVKENNNLIQKIEQQQQLQLRELNELKEQNKQILAEAENNQLVFN 1722

Query: 560  LTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDV-YKKMIEMENLAETRLKAISL 618
             TE   +L +++A L+++  ++  + ++ +  + ++     +K  E     +  L     
Sbjct: 1723 QTEA--NLQEQIAYLKQQL-DISNNKLEEEHNKFLQKFTNLQKEAEQNTQKQVLLNEALR 1779

Query: 619  LESQKFDLVQELHILQQKYDEVEDKLADISQ--LQSDQVCSEIKSVHLEEQIDALSASKK 676
             E  K +  Q LH  +    + E++L + +Q  LQ  Q   E KS+    Q       + 
Sbjct: 1780 DEKWKAEKEQILHSHKMTISQKENELFEKNQELLQMKQQLEEFKSLSHTYQTKLKEIQES 1839

Query: 677  ELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISEL- 735
                 + N ++  +QL     +  + K+++ N L   +QE  + T KL   + E +++  
Sbjct: 1840 NEKQSVINTQIFTKQLDQVNTEKNSLKQNLEN-LNAKLQEKAEETQKLIVQNGEYLTKAH 1898

Query: 736  -LAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYS 794
             L ++N E+++KI     +   IQ++D YI+    E+ + K  I  L E  + +  +   
Sbjct: 1899 QLEQLNQEKETKI---IQLSKNIQQQDTYIQKTAQEIQQKKDIIQTLNEEYSKVIQQNEQ 1955

Query: 795  LERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKK 854
            L+ +  +  + L EKQ       I + + V RL        +V K  LE E ENK  ++ 
Sbjct: 1956 LKHQISETQTQL-EKQSI-----IHKQKEVERL-------ELVHKSKLE-ELENKHNEEL 2001

Query: 855  NQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQ-LRDLESNLKRITHE 913
            N+I  EE + +   L + +Q  ++ +E+       E ++ K  T+ L++    L++   E
Sbjct: 2002 NKIF-EERRIMLEQLEEQKQQKDSEIEELCLKYAEEIDNFKKLTKNLQNQNEFLEKENAE 2060

Query: 914  HQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIEN 973
             + L  Q +  + + + E N + E        + E+YEK +E    LE  L++    IE 
Sbjct: 2061 KEELCNQFQVALNEFKQELNKRDELLY-----IQEEYEKLVEVNKILENDLEKKTKMIEE 2115

Query: 974  LNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKIN 1033
              +N+ +  +   E+  K +  Q+ +  D  +  + E  +   +  Q  ++       + 
Sbjct: 2116 SKVNLIQAKRDMQEM--KKILDQKNKEIDVQKNELKEFYERTQVFAQTRDK------DVK 2167

Query: 1034 NAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIK 1093
              +  Y  ++ ++   ++Q+  + E M++    +S    +  Q N+E    +R+     K
Sbjct: 2168 EVKDQYCKLLDEHNKIMSQYNEQSEKMDKLKVEISDYAKEKAQINQE----IRKLQSNEK 2223

Query: 1094 ELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQE 1153
            +LK+ +L   + + K     ++   + + +D  NV                   ++ I+ 
Sbjct: 2224 KLKQ-QLNDMIEVNKR----LNEDNKKLEEDYENVQRELQYIGGH------NNPDQKIKM 2272

Query: 1154 RSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNL 1213
             + ++E++  L  E +E  T++ Q+   N +L        +QI QL++     N +  N 
Sbjct: 2273 FNKIKEENTLLKNEKKELSTQLAQIAEENKQLL-------KQIEQLRT-----NPDRSNP 2320

Query: 1214 LSTVAELRSSISSAVDQRGFEIAELWKQ 1241
            L  +   R   SS+   +  ++ EL KQ
Sbjct: 2321 LKNIGNQRFGNSSSSTDKSIQM-ELEKQ 2347



 Score =  113 bits (271), Expect = 5e-23
 Identities = 182/936 (19%), Positives = 401/936 (42%), Gaps = 82/936 (8%)

Query: 151  IKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXX 210
            I+E  N +  L+ +++ ++T      EK++E++Q+ E + +                   
Sbjct: 1532 IEEHQNIIDELKTEIEGLKT---QRYEKLSEQEQLYENQQQENRLLVKQI---------- 1578

Query: 211  XEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLE 270
             E+ K+++    E  IA   E ++ +Q+   D++ K +   S +E NK+ + ++  I   
Sbjct: 1579 -ENLKKEIVNKSEQLIAEREEQQETQQQF--DMQIKQIEEKSSQEINKIQQESQEAIETA 1635

Query: 271  HSK---LAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKK 327
              +   L ++LE+              L +Q  E   +EK +  ++ +  +    E  ++
Sbjct: 1636 EKQILELKRQLEKIIKQKEEELQQANKLVEQVKEQLLQEKNQSVKENN-NLIQKIEQQQQ 1694

Query: 328  IELLEHLNCQIRQTNKEL-----ENKLATMGTESKAVSSPSKKGSPL-ISRKSGRNTASK 381
            ++L E LN ++++ NK++      N+L    TE+      +     L IS        +K
Sbjct: 1695 LQLRE-LN-ELKEQNKQILAEAENNQLVFNQTEANLQEQIAYLKQQLDISNNKLEEEHNK 1752

Query: 382  MKSPWSQLSSETLNQDTDKKINKNEI-------AKLEMVIQSLNKDLVDKEYVISEKDTX 434
                ++ L  E   Q+T K++  NE        A+ E ++ S    +  KE  + EK+  
Sbjct: 1753 FLQKFTNLQKEA-EQNTQKQVLLNEALRDEKWKAEKEQILHSHKMTISQKENELFEKNQE 1811

Query: 435  XXXXXXXXXGKDTLIAQLQL---EHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELND 491
                        +L    Q    E Q+  E  S+I+    T+ ++++   +  LKQ L +
Sbjct: 1812 LLQMKQQLEEFKSLSHTYQTKLKEIQESNEKQSVINTQIFTKQLDQVNTEKNSLKQNLEN 1871

Query: 492  -----EIKDVNVKDLI----EKLKSAEEQITQLNDE----IDAANKNMIKVKSNHKLKLK 538
                 + K    + LI    E L  A  Q+ QLN E    I   +KN+ +  +  +   +
Sbjct: 1872 LNAKLQEKAEETQKLIVQNGEYLTKAH-QLEQLNQEKETKIIQLSKNIQQQDTYIQKTAQ 1930

Query: 539  QMQKTIDNFSKVSDSNKEIVRLTEEL-HHLSQKVAELEEEK---GNLQLHLVDYDSGRMI 594
            ++Q+  D    +++   ++++  E+L H +S+   +LE++       ++  ++      +
Sbjct: 1931 EIQQKKDIIQTLNEEYSKVIQQNEQLKHQISETQTQLEKQSIIHKQKEVERLELVHKSKL 1990

Query: 595  ESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQ-LQSD 653
            E    K   E+  + E R   +  LE QK     E+  L  KY E  D    +++ LQ+ 
Sbjct: 1991 EELENKHNEELNKIFEERRIMLEQLEEQKQQKDSEIEELCLKYAEEIDNFKKLTKNLQNQ 2050

Query: 654  QVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNY 713
                E ++   EE  +    +  E     + L    E LY     ++ + E ++    N 
Sbjct: 2051 NEFLEKENAEKEELCNQFQVALNEFK---QELNKRDELLY-----IQEEYEKLVEV--NK 2100

Query: 714  IQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDL--YIENIESEL 771
            I EN DL  K + +   K++ + AK + +E  KI  Q   +  +Q+ +L  + E  +   
Sbjct: 2101 ILEN-DLEKKTKMIEESKVNLIQAKRDMQEMKKILDQKNKEIDVQKNELKEFYERTQVFA 2159

Query: 772  SKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLM 831
                  +  +++    + D    +  + ++    + + +   S+Y  ++ ++   +  L 
Sbjct: 2160 QTRDKDVKEVKDQYCKLLDEHNKIMSQYNEQSEKMDKLKVEISDYAKEKAQINQEIRKLQ 2219

Query: 832  DHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAES 891
             +++ +++QL ++   NK L + N+ L E+ +N+Q  L  +  H N   +K    +  + 
Sbjct: 2220 SNEKKLKQQLNDMIEVNKRLNEDNKKLEEDYENVQRELQYIGGHNNP-DQKIKMFNKIKE 2278

Query: 892  ESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYE 951
            E+T  + + ++L + L +I  E++ L+    K+IE L     T  + +   K + N+++ 
Sbjct: 2279 ENTLLKNEKKELSTQLAQIAEENKQLL----KQIEQL----RTNPDRSNPLKNIGNQRFG 2330

Query: 952  KNIEYVTQ-LEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINE 1010
             +     + ++ +L++  N  + L   + + N++ +++       +Q Q        I+ 
Sbjct: 2331 NSSSSTDKSIQMELEKQINENKKLQDIIIQTNQI-IQMGQSSKGLKQFQKSSLDRDLISG 2389

Query: 1011 INKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDY 1046
            + ++   +  K+ +I  L  +++   + Y  +   Y
Sbjct: 2390 VKQIVQEILDKENKIKNLTGELDAKTIKYTELEKKY 2425



 Score = 97.9 bits (233), Expect = 2e-18
 Identities = 198/995 (19%), Positives = 416/995 (41%), Gaps = 107/995 (10%)

Query: 49   ERQIKFERAQKCLENAALVS-KRIKEHRKATAELLGRPFVPGISESLANTLKQKEILMEK 107
            E Q +F+   K +E  +     +I++  +   E   +  +  +   L   +KQKE  +++
Sbjct: 1601 ETQQQFDMQIKQIEEKSSQEINKIQQESQEAIETAEKQILE-LKRQLEKIIKQKEEELQQ 1659

Query: 108  ----IKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNALSVLQV 163
                ++Q KE   +     V+               QL ++  L    K+    L+  + 
Sbjct: 1660 ANKLVEQVKEQLLQEKNQSVKENNNLIQKIEQQQQLQLRELNELKEQNKQ---ILAEAEN 1716

Query: 164  KMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQE 223
               +   T  +LQE+I    Q ++  N                     E   Q+   + E
Sbjct: 1717 NQLVFNQTEANLQEQIAYLKQQLDISNNKLEEEHNKFLQKFTNLQKEAEQNTQKQVLLNE 1776

Query: 224  NFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXX 283
                 + +WK EK+++L    S  + IS  E  N+L     FE + E  ++ Q+LE+   
Sbjct: 1777 AL--RDEKWKAEKEQIL---HSHKMTISQKE--NEL-----FEKNQELLQMKQQLEEFKS 1824

Query: 284  XXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNK 343
                           + +   +E  E  EK S  + N    TK+++ +      ++Q  +
Sbjct: 1825 LS------------HTYQTKLKEIQESNEKQS--VINTQIFTKQLDQVNTEKNSLKQNLE 1870

Query: 344  ELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKIN 403
             L  KL     E++ +    + G  L           + ++   QLS     QDT  +  
Sbjct: 1871 NLNAKLQEKAEETQKLIV--QNGEYLTKAHQLEQLNQEKETKIIQLSKNIQQQDTYIQKT 1928

Query: 404  KNEIAKLEMVIQSLNKD---LVDKEYVISEK--DTXXXXXXXXXXGKDTLIAQLQLEHQQ 458
              EI + + +IQ+LN++   ++ +   +  +  +T           K   + +L+L H+ 
Sbjct: 1929 AQEIQQKKDIIQTLNEEYSKVIQQNEQLKHQISETQTQLEKQSIIHKQKEVERLELVHKS 1988

Query: 459  HMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEI--KDVNVKDLIEKLKSAEEQITQLN 516
             +E     H     E++N+I + +  + ++L ++   KD  +++L  K     +   +L 
Sbjct: 1989 KLEELENKH----NEELNKIFEERRIMLEQLEEQKQQKDSEIEELCLKYAEEIDNFKKLT 2044

Query: 517  DEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQ--KVAEL 574
              +   N+ + K  +  +    Q Q  ++ F +  +   E++ + EE   L +  K+ E 
Sbjct: 2045 KNLQNQNEFLEKENAEKEELCNQFQVALNEFKQELNKRDELLYIQEEYEKLVEVNKILEN 2104

Query: 575  EEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQ 634
            + EK   +  +++     +I++   + M EM+ + + + K I +   QK +L +E +   
Sbjct: 2105 DLEK---KTKMIEESKVNLIQAK--RDMQEMKKILDQKNKEIDV---QKNEL-KEFYERT 2155

Query: 635  QKYDEVEDKLADISQLQSDQVCSEIKSVH-LEEQIDALSASKKELALVIENLKLDKEQLY 693
            Q + +  DK  D+ +++ DQ C  +   + +  Q +  S    +L + I +   +K Q+ 
Sbjct: 2156 QVFAQTRDK--DVKEVK-DQYCKLLDEHNKIMSQYNEQSEKMDKLKVEISDYAKEKAQIN 2212

Query: 694  GTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSA--EKISELLAKIN-HEEQSKIQTQ 750
              I+ L+++++ +  +L + I+ N  L +  +K+    E +   L  I  H    +    
Sbjct: 2213 QEIRKLQSNEKKLKQQLNDMIEVNKRLNEDNKKLEEDYENVQRELQYIGGHNNPDQKIKM 2272

Query: 751  FGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQ 810
            F    KI+E +  ++N + ELS   ++I   EE+  +++     L    D+         
Sbjct: 2273 FN---KIKEENTLLKNEKKELSTQLAQIA--EENKQLLKQIE-QLRTNPDRSNPLKNIGN 2326

Query: 811  KAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLS 870
            + +   +   D+     ++ M+    +EKQ+    +ENK+LQ    I+++ NQ +Q+  S
Sbjct: 2327 QRFGNSSSSTDK-----SIQME----LEKQI----NENKKLQ---DIIIQTNQIIQMGQS 2370

Query: 871  D--MQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIED- 927
               ++Q   + +++    DL        Q ++ D E+ +K +T E     + K  E+E  
Sbjct: 2371 SKGLKQFQKSSLDR----DLISGVKQIVQ-EILDKENKIKNLTGELDAKTI-KYTELEKK 2424

Query: 928  -LEIEFNTQIESAIRD--KKVLNEKY------EKNIEYVTQLEAQLQEYKN-NIENLNMN 977
             L+++ N +  S + +  ++   +++        +I+   Q   Q   Y+N N  N N+N
Sbjct: 2425 YLQLQLNVKDSSYLNNINRERSKDRFGAALGSNSSIQQQQQPLQQPMSYQNLNHLNQNIN 2484

Query: 978  VEELNKMNLELIDKHVQKQQTQSPDYTEQYINEIN 1012
            ++  +    + I +H  +Q  Q P+    Y N  N
Sbjct: 2485 LQNYSIQQQQQIQQHQAQQNQQKPNRLNFYNNYNN 2519



 Score = 70.1 bits (164), Expect = 5e-10
 Identities = 152/785 (19%), Positives = 321/785 (40%), Gaps = 75/785 (9%)

Query: 859  LEENQNLQISLSDMQQHYNALVEKAN-RTDLAESESTKYQTQLRD-LESNLK-RITHEHQ 915
            L+E  N+  SLS +    NALVE  N R        +K    L+D L  N K R+     
Sbjct: 304  LKEGCNINKSLSILGNVINALVEVDNGRARHIHYRDSKLTFFLKDSLGGNSKTRVIANIS 363

Query: 916  TLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVT------QLE-AQLQE-- 966
                  ++ +  L+     ++   I++K  +NE +  N+E +       +LE  Q +E  
Sbjct: 364  PASSAFQETLSTLKFAKRAKL---IKNKVQINEDHSGNVESLNNEIKKLRLENLQFRELL 420

Query: 967  ----------YKNNIENLNMNVEELNKMNLELI-DKHVQKQQTQS--PDYTEQYINEINK 1013
                        NN +  + ++ E  K NL +I D++++ Q+T+     Y EQ      K
Sbjct: 421  LKGGSIPSFFQPNNSQPQSPSIRE-QKNNLRMIKDENIKMQETEELCQHYLEQAQELELK 479

Query: 1014 LNALL-KQKDE--EIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQ 1070
            +N  + K KD+   ++   +K    +  Y S++    +K+ +    L+N +   ++V + 
Sbjct: 480  MNYNMGKTKDQLMHLMKYVEKFQQNEYQYRSIIKLQRAKIERVELMLKNKQLTKEQVQEF 539

Query: 1071 LLDSKQHNE-ELQILVREQDDQI--KELKETKLTFEMNIPKTE--GMIISSTIEPMSDDA 1125
              + ++  + EL  L    ++Q+   +L +  +  +  + K +  G  I   +    D  
Sbjct: 540  FNEDREKTQKELNNLRELLENQMYCAKLLDENVELQQQVEKIQEPGRSIFQQLTNNVDVL 599

Query: 1126 NNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTK-IIQLETLNTE 1184
             ++             L+   E+    +++   ++S KL  +L +   +    +E LN+E
Sbjct: 600  KSIQNKLEQNIEQRVRLQKVVEDLEESKKNASPDRSKKLEFQLTQIEKEHKSAVENLNSE 659

Query: 1185 LTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLA 1244
            L    +  ++++N  +  ++Q+  EN  +LS   E    +      +  E     K+ +A
Sbjct: 660  L----LTQKQKLNDQERMIDQIVEEN-QMLSKELEQMKLMQEFKQAQHEETVHQLKKLIA 714

Query: 1245 QREADFQKTEHELRVQLSAFESKYEQLLD--------SVQSSTQEE---TNKIVTMEQVT 1293
            ++     +   ELR++      + +QL          S +S  Q +     K    E+  
Sbjct: 715  EKSNVTDEMNQELRLRNIDLVEQIKQLQQQNLLLNERSKESEKQRQDMAEEKKQAHEKYL 774

Query: 1294 SLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKV-------AFXXXXXXXXXXXX 1346
                K  ++  HL+   ++     N+ E     I+DE +                     
Sbjct: 775  KYLEKYNEETTHLQASIQELTSNFNEKEFENLRIKDEVIQGNERIRELESNISQAKQVQD 834

Query: 1347 XXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELT 1406
                ++  +    +Q++EQ ++ + E + Q K               R N+ E    + T
Sbjct: 835  SLQQEIEQKKNQIEQLEEQ-LIELEEADNQRKDLQEEIETLNETLNFRENELEEMKKQKT 893

Query: 1407 HQL----ELKDSEIYQKTHEYTITLTQRNDEFE--NVRQQLVEYEKRIEDLTYEKESELA 1460
              L    EL+ +++  +  E   TL  R +E E  N  Q     E+++E++  + E E  
Sbjct: 894  QLLNQIQELQAAKV--QIEELVQTLKMRIEELESQNNEQNNKLLEEKVEEVK-KLEDEKV 950

Query: 1461 ILRLKMHE--NANHYETMQKESEIERVKLIEELNVKITESVS-LNKQVAELNKALEEEVA 1517
            ++  +++E       + +  ++++E++K +E+  V + + ++ ++ +   + + LE E+ 
Sbjct: 951  VIEQELNEIRKTKEADNIVIQNKLEQIKSLEQEKVFVQQKINEISDEKERITQVLEGEIK 1010

Query: 1518 KTNEMQTALENQEIEIVTLND-EITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTM 1576
               E     ++Q  E++     EI  L++ V+   S IQK +   ++ K   +E      
Sbjct: 1011 ILKEKLLLEDDQNQEVINQKQTEIEQLRSQVQQLKSSIQKEIESFNNEKTKLEENFKKEK 1070

Query: 1577 NKELL 1581
             + LL
Sbjct: 1071 QETLL 1075


>UniRef50_UPI00006CD2DD Cluster: Viral A-type inclusion protein repeat
            containing protein; n=1; Tetrahymena thermophila
            SB210|Rep: Viral A-type inclusion protein repeat
            containing protein - Tetrahymena thermophila SB210
          Length = 1379

 Score =  172 bits (419), Expect = 6e-41
 Identities = 234/1153 (20%), Positives = 508/1153 (44%), Gaps = 108/1153 (9%)

Query: 468  VGTNTEDVNEIAKVQEQLKQEL-NDEIKDVNVKDLIEKL-KSAEEQITQLNDEIDAANKN 525
            +  N   V ++  + E+LK +  N E      KD  E+L K  ++ I +  + +      
Sbjct: 64   IENNQTIVKKVGNLAEELKVKFANLETDYDQCKDEKEELEKKYKQSIEKYGEMMKNYEHQ 123

Query: 526  MIKVKSNHKLKLKQMQKTIDNFSKVSDSNKE-IVRLTEELHHLSQKVAELEEEKGNLQLH 584
            +I +++ + ++++Q+Q+ ID   K ++  ++  + + +++    Q   +++ +   +  H
Sbjct: 124  IISLENENNIRIQQLQQQIDELKKQNEEKEQSYLNMQQQIKQDKQSFDDIQNKYEEINKH 183

Query: 585  LVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHIL---QQKYDEVE 641
              + +  +   SD + K++ +           +     K D+  + HI+   QQ + ++ 
Sbjct: 184  --NQEQFKQ-NSDQWVKLVNLTEEVIFNFYNSNFFTENKDDISSQTHIILQHQQTFQQLI 240

Query: 642  DK----LADISQLQ---SDQVCSEIKSVH------LEEQIDALSASKKELALVIENLKLD 688
            +K    LA+  +     SD+  ++IKS +        +++  L    +        L  +
Sbjct: 241  EKYVTFLAEQKEKNEAISDEAFNKIKSENGNGVQKTNQRVQDLQQKFEAYQQQFNKLNSE 300

Query: 689  KEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQ 748
             ++    +++ +   ED+ N+L N   +  +L ++ +K   E I +L  +I   +Q   +
Sbjct: 301  SQENETKLQETKKQLEDLQNELGNKNNQIQELNEQHQKSQTE-IQKLNEQITSNQQRIEE 359

Query: 749  TQFGIDAKIQERDLYIENIESELSKYKSRI---CRLEESIAVMEDRRYSLERKADQLGSY 805
             Q   +  + E+D  I  I+ +LS    +I     ++  +    +    LE+  +Q  S 
Sbjct: 360  LQKNENILV-EKDKNINEIKEQLSALNQQIEGFKDIQNKLDTKTEEFEKLEKDFNQQKSE 418

Query: 806  LQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNL 865
            L+EK K+  E   + + L  ++  +++  +  +KQL ++   N  LQ  N+    EN+ L
Sbjct: 419  LEEKIKSKDE---EIENLSKKIQDIVEQQQEKQKQLDDL---NSNLQNSNK----ENEQL 468

Query: 866  QISLSDMQQHYN-ALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKE 924
            +  ++D +   N +  ++  +++  ++E  + Q QL D +   ++   E + L    K++
Sbjct: 469  KQEINDFKNKINNSNQDQEQQSNQLKAELKQTQEQLNDSQQKFEQADKELKDL----KQQ 524

Query: 925  IEDLEIEFNTQIESA--IRDK-KVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEEL 981
            IED +++ N + + +  ++D+ K  NEK  ++ + + Q++    + K N  +L   V+E 
Sbjct: 525  IEDEKVKLNDKSQESENLKDQLKSANEKLNESQQKLEQIQKNFDDLKQN-NDLQKIVDE- 582

Query: 982  NKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMS 1041
             +   E +++ +++ +TQ     EQ   ++ +LN    +K+E     NQ +   +     
Sbjct: 583  KQQKCEELERELKELKTQQ----EQVTAQVQQLNV---EKEEIQTKFNQ-VEQEKEQLKK 634

Query: 1042 MVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKET--K 1099
               +    L+Q   + EN E+E+  + + + + ++   ++QI  +E+D Q+ + K T   
Sbjct: 635  QEQEKIDLLSQAKQEKENNEQEINNLKQTIANLEKERTDIQIQSQEKDKQLDDAKHTLEN 694

Query: 1100 LTFEMNIPKTEGMIISSTIEP---MSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSV 1156
            L  E+   K +   I    E    +  +   +             L  + E E  +++  
Sbjct: 695  LNKEIEQLKNQNQAIGDVNEKNKQLESEITQIKSEIEQKNTEIQSLNSKNETEISEKKQQ 754

Query: 1157 LQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLST 1216
            L++ + ++N +L E   +I QL T N  L      NQ   N  ++KL  LN+E +     
Sbjct: 755  LEDHTKQVN-QLNE---QIHQLSTENENLKNEIQTNQ---NISQTKLTDLNSEIEGFQKE 807

Query: 1217 VAELRSSISSAVDQ-RGFEIA-ELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDS 1274
            + E +  +     Q +G ++  E  ++ L ++  + QK   +L+      ES  EQ  ++
Sbjct: 808  IEETKLQLDDKNTQLKGLQVKLEALEKQLLEKNEEIQKVNQQLK------ES--EQKHEA 859

Query: 1275 VQSSTQEETNKIVTMEQVTSLQNKLQ-DKEEHLRNLQEKYADVINQIEILRSEIEDEKVA 1333
            +Q   +E  N + T+E+     N++Q D  + + +L++K  D+  Q++    EI   K  
Sbjct: 860  IQKQNEELQNSLKTLEEKD--YNQIQNDLNQQVSDLKQKEQDLNKQLDQKLQEINQIKQQ 917

Query: 1334 FXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXX 1393
                              ++  NQ+  Q QEQ I  I  +  Q ++              
Sbjct: 918  LSNETSDFMKKNVQLQQTIQQLNQTISQYQEQ-IERIKTDLYQSQQEKSQLQSKLNEANR 976

Query: 1394 RVNDAEA---KVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIED 1450
             + + E    K +E+  +LE  + ++    H Y +     + E  +V +  +++ K  + 
Sbjct: 977  EIQNKEDDLNKKVEIIAELEQNNKDLKINLHNYEVKSYDLDKERFDVLEIQIQHNKE-QQ 1035

Query: 1451 LTYEKESELAILRLK------MHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQ 1504
            + Y K++E  I +L+      + +  +  E +QKE + E+V + EE++ K   ++     
Sbjct: 1036 VQY-KQAEEKIQKLEEEIKKLLADKTDSLEKLQKEIKTEQV-IGEEMSKKFRSNL----- 1088

Query: 1505 VAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDT 1564
             AEL         + N  Q +LEN +  I  L + +         SS+KI +      D 
Sbjct: 1089 -AEL---------QINNEQNSLENSQKTINQLAEVVLRKVKDCFYSSTKIVQISRLFYDG 1138

Query: 1565 KQGRDEQLDNTMN 1577
              GR+   DN ++
Sbjct: 1139 SDGRNASQDNALS 1151



 Score =  170 bits (414), Expect = 2e-40
 Identities = 232/1035 (22%), Positives = 453/1035 (43%), Gaps = 76/1035 (7%)

Query: 583  LHLVDYDSGRMIESD--VYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEV 640
            + + D D+   IE++  + KK+    NLAE      + LE+       E   L++KY + 
Sbjct: 53   IEITDEDNDPEIENNQTIVKKV---GNLAEELKVKFANLETDYDQCKDEKEELEKKYKQS 109

Query: 641  EDKLADISQLQSDQVCS-----EIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGT 695
             +K  ++ +    Q+ S      I+   L++QID L    +E      N++   +Q   +
Sbjct: 110  IEKYGEMMKNYEHQIISLENENNIRIQQLQQQIDELKKQNEEKEQSYLNMQQQIKQDKQS 169

Query: 696  IKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELL-AKINHEEQSKIQTQFGID 754
              D++N  E+I    Q   ++N D   KL  ++ E I     +    E +  I +Q  I 
Sbjct: 170  FDDIQNKYEEINKHNQEQFKQNSDQWVKLVNLTEEVIFNFYNSNFFTENKDDISSQTHII 229

Query: 755  AKIQER-DLYIENIESELSKYKSRICRL-EESIAVMEDRRYSLERKADQLGSYLQEKQKA 812
             + Q+     IE   + L++ K +   + +E+   ++    +  +K +Q    LQ+K +A
Sbjct: 230  LQHQQTFQQLIEKYVTFLAEQKEKNEAISDEAFNKIKSENGNGVQKTNQRVQDLQQKFEA 289

Query: 813  Y-SEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKN---QILLEENQNLQIS 868
            Y  ++     E       L +  + +E    E+ ++N ++Q+ N   Q    E Q L   
Sbjct: 290  YQQQFNKLNSESQENETKLQETKKQLEDLQNELGNKNNQIQELNEQHQKSQTEIQKLNEQ 349

Query: 869  LSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDL 928
            ++  QQ    L +  N     +    + + QL  L   ++    + Q  +  K +E E L
Sbjct: 350  ITSNQQRIEELQKNENILVEKDKNINEIKEQLSALNQQIEGF-KDIQNKLDTKTEEFEKL 408

Query: 929  EIEFNTQIESAIRDK-KVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLE 987
            E +FN Q +S + +K K  +E+ E   + +  +  Q QE +  +++LN N++  NK N E
Sbjct: 409  EKDFNQQ-KSELEEKIKSKDEEIENLSKKIQDIVEQQQEKQKQLDDLNSNLQNSNKEN-E 466

Query: 988  LIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSM---VS 1044
             + + +   + +  +  +    + N+L A LKQ  E++    QK   A      +   + 
Sbjct: 467  QLKQEINDFKNKINNSNQDQEQQSNQLKAELKQTQEQLNDSQQKFEQADKELKDLKQQIE 526

Query: 1045 DYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQ----ILVREQDDQ----IKELK 1096
            D + KL   + + EN++++++  +++L +S+Q  E++Q     L +  D Q     K+ K
Sbjct: 527  DEKVKLNDKSQESENLKDQLKSANEKLNESQQKLEQIQKNFDDLKQNNDLQKIVDEKQQK 586

Query: 1097 ETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSV 1156
              +L  E+   KT+   +++ ++ ++ +   +             LK QE+E+ I   S 
Sbjct: 587  CEELERELKELKTQQEQVTAQVQQLNVEKEEIQTKFNQVEQEKEQLKKQEQEK-IDLLSQ 645

Query: 1157 LQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLST 1216
             +++      E+      I  LE   T++        +Q++  K  LE LN E + L + 
Sbjct: 646  AKQEKENNEQEINNLKQTIANLEKERTDIQIQSQEKDKQLDDAKHTLENLNKEIEQLKNQ 705

Query: 1217 VAELRSSISSAVDQRGFEIAELWKQHLAQREADFQ----KTEHEL---RVQLSAFESKYE 1269
               +   ++    Q   EI ++ K  + Q+  + Q    K E E+   + QL     +  
Sbjct: 706  NQAI-GDVNEKNKQLESEITQI-KSEIEQKNTEIQSLNSKNETEISEKKQQLEDHTKQVN 763

Query: 1270 QLLDSV-QSSTQEET--NKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSE 1326
            QL + + Q ST+ E   N+I T + ++  Q KL D    +   Q++  +   Q++   ++
Sbjct: 764  QLNEQIHQLSTENENLKNEIQTNQNIS--QTKLTDLNSEIEGFQKEIEETKLQLDDKNTQ 821

Query: 1327 IEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQE--QSILNINEE--NAQLKKSSX 1382
            ++  +V                  +++  NQ  K+ ++  ++I   NEE  N+       
Sbjct: 822  LKGLQVKL----EALEKQLLEKNEEIQKVNQQLKESEQKHEAIQKQNEELQNSLKTLEEK 877

Query: 1383 XXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQ-------KTHEYTITLTQRNDEFE 1435
                       +V+D + K  +L  QL+ K  EI Q       +T ++     Q     +
Sbjct: 878  DYNQIQNDLNQQVSDLKQKEQDLNKQLDQKLQEINQIKQQLSNETSDFMKKNVQLQQTIQ 937

Query: 1436 NVRQQLVEYEKRIEDL---TYEKESELAILRLKMHENANHYETMQKESEI-ERVKLIEEL 1491
             + Q + +Y+++IE +    Y+ + E + L+ K++E AN  E   KE ++ ++V++I EL
Sbjct: 938  QLNQTISQYQEQIERIKTDLYQSQQEKSQLQSKLNE-ANR-EIQNKEDDLNKKVEIIAEL 995

Query: 1492 --NVKITESVSLNKQVA--ELNK----ALEEEVAKTNEMQTALENQEIEIVTLNDEITNL 1543
              N K  +    N +V   +L+K     LE ++    E Q   +  E +I  L +EI  L
Sbjct: 996  EQNNKDLKINLHNYEVKSYDLDKERFDVLEIQIQHNKEQQVQYKQAEEKIQKLEEEIKKL 1055

Query: 1544 QNMVRASSSKIQKHV 1558
                  S  K+QK +
Sbjct: 1056 LADKTDSLEKLQKEI 1070



 Score =  134 bits (325), Expect = 1e-29
 Identities = 198/970 (20%), Positives = 421/970 (43%), Gaps = 97/970 (10%)

Query: 634  QQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLY 693
            Q+K  E +++     Q  ++Q  +E +    + QI + S  K ++ +  E+   + E   
Sbjct: 9    QEKQVEAQNEEQKQEQENNEQKENESEQAQTDPQISSGSNQKFDIEITDEDNDPEIENNQ 68

Query: 694  GTIKDLENDKEDIMNKLQN----YIQ--ENMDLTDKLEKMSAEKISELLAKINHEEQSKI 747
              +K + N  E++  K  N    Y Q  +  +  +K  K S EK  E++    H+  S +
Sbjct: 69   TIVKKVGNLAEELKVKFANLETDYDQCKDEKEELEKKYKQSIEKYGEMMKNYEHQIIS-L 127

Query: 748  QTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQ 807
            + +  I  +IQ+    I+ ++ +  + +     +++ I   +     ++ K +++  + Q
Sbjct: 128  ENENNI--RIQQLQQQIDELKKQNEEKEQSYLNMQQQIKQDKQSFDDIQNKYEEINKHNQ 185

Query: 808  EKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQI 867
            E+ K  S+  ++   LVN          + E+ +    + N   + K+ I  + +  LQ 
Sbjct: 186  EQFKQNSDQWVK---LVN----------LTEEVIFNFYNSNFFTENKDDISSQTHIILQ- 231

Query: 868  SLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIED 927
                 QQ +  L+EK   T LAE +           +    +I  E+   + +  + ++D
Sbjct: 232  ----HQQTFQQLIEKYV-TFLAEQKEKNEAIS----DEAFNKIKSENGNGVQKTNQRVQD 282

Query: 928  LEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLE 987
            L+ +F    E+  +    LN + ++N   + + + QL++ +N + N N  ++ELN+ +  
Sbjct: 283  LQQKF----EAYQQQFNKLNSESQENETKLQETKKQLEDLQNELGNKNNQIQELNEQH-- 336

Query: 988  LIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYE 1047
                  QK QT+     EQ  +   ++  L  QK+E I+    K  N     +S ++   
Sbjct: 337  ------QKSQTEIQKLNEQITSNQQRIEEL--QKNENILVEKDKNINEIKEQLSALNQQI 388

Query: 1048 SKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKEL-KETKLTFEMNI 1106
                    KL+   EE +++ K   D  Q   EL+  ++ +D++I+ L K+ +   E   
Sbjct: 389  EGFKDIQNKLDTKTEEFEKLEK---DFNQQKSELEEKIKSKDEEIENLSKKIQDIVEQQQ 445

Query: 1107 PKTEGMI-ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLN 1165
             K + +  ++S ++  + +   +                 +E++  Q ++ L++   +LN
Sbjct: 446  EKQKQLDDLNSNLQNSNKENEQLKQEINDFKNKINNSNQDQEQQSNQLKAELKQTQEQLN 505

Query: 1166 TELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSIS 1225
               Q+        E  + EL   D+  ++QI   K KL   + E++NL   +      ++
Sbjct: 506  DSQQK-------FEQADKELK--DL--KQQIEDEKVKLNDKSQESENLKDQLKSANEKLN 554

Query: 1226 SAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNK 1285
             +  Q+  E  +     L Q   D QK   E + +    E + ++L    +  T +    
Sbjct: 555  ES--QQKLEQIQKNFDDLKQNN-DLQKIVDEKQQKCEELERELKELKTQQEQVTAQVQQL 611

Query: 1286 IVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXX 1345
             V  E++ +  N+++ ++E L+  +++  D+++Q +  +   E E               
Sbjct: 612  NVEKEEIQTKFNQVEQEKEQLKKQEQEKIDLLSQAKQEKENNEQE----INNLKQTIANL 667

Query: 1346 XXXXXDLRTENQSY-KQMQE--QSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKV 1402
                 D++ ++Q   KQ+ +   ++ N+N+E  QLK  +            +    E+++
Sbjct: 668  EKERTDIQIQSQEKDKQLDDAKHTLENLNKEIEQLKNQNQAIGDVNE----KNKQLESEI 723

Query: 1403 LELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKES---EL 1459
             ++  ++E K++EI     +    ++++  + E+  +Q+ +  ++I  L+ E E+   E+
Sbjct: 724  TQIKSEIEQKNTEIQSLNSKNETEISEKKQQLEDHTKQVNQLNEQIHQLSTENENLKNEI 783

Query: 1460 A----ILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKAL--- 1512
                 I + K+ +  +  E  QKE  IE  KL  +L+ K T+   L  ++  L K L   
Sbjct: 784  QTNQNISQTKLTDLNSEIEGFQKE--IEETKL--QLDDKNTQLKGLQVKLEALEKQLLEK 839

Query: 1513 EEEVAKTNEMQTALENQEIEIVTLNDEITN-LQNMVRASSSKIQKHVSF-ASDTKQGRDE 1570
             EE+ K N+     E +   I   N+E+ N L+ +     ++IQ  ++   SD KQ   +
Sbjct: 840  NEEIQKVNQQLKESEQKHEAIQKQNEELQNSLKTLEEKDYNQIQNDLNQQVSDLKQKEQD 899

Query: 1571 QLDNTMNKEL 1580
                 +NK+L
Sbjct: 900  -----LNKQL 904



 Score =  127 bits (306), Expect = 3e-27
 Identities = 180/928 (19%), Positives = 402/928 (43%), Gaps = 82/928 (8%)

Query: 705  DIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYI 764
            +  N+ Q   QEN +  +  E   A+   ++ +  N +   +I T    D +I+     +
Sbjct: 14   EAQNEEQKQEQENNEQKEN-ESEQAQTDPQISSGSNQKFDIEI-TDEDNDPEIENNQTIV 71

Query: 765  ENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELV 824
            + + +   + K +   LE      +D +  LE+K  Q      E  K Y E+ I   E  
Sbjct: 72   KKVGNLAEELKVKFANLETDYDQCKDEKEELEKKYKQSIEKYGEMMKNY-EHQIISLENE 130

Query: 825  NRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKAN 884
            N + +     + +++Q+ E++ +N+E ++    + ++ +  + S  D+Q  Y   + K N
Sbjct: 131  NNIRI-----QQLQQQIDELKKQNEEKEQSYLNMQQQIKQDKQSFDDIQNKYEE-INKHN 184

Query: 885  RTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKK 944
            +      +++    +L +L   +  I + + +    + K+      + ++Q    ++ ++
Sbjct: 185  QEQF--KQNSDQWVKLVNLTEEV--IFNFYNSNFFTENKD------DISSQTHIILQHQQ 234

Query: 945  VLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYT 1004
               +  EK   YVT L  Q ++ +   +     ++  N   ++  ++ VQ  Q +   Y 
Sbjct: 235  TFQQLIEK---YVTFLAEQKEKNEAISDEAFNKIKSENGNGVQKTNQRVQDLQQKFEAYQ 291

Query: 1005 EQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEM 1064
            +Q+    NKLN+  ++ + ++    +++ + Q    + + +  +++ +   + +  + E+
Sbjct: 292  QQF----NKLNSESQENETKLQETKKQLEDLQ----NELGNKNNQIQELNEQHQKSQTEI 343

Query: 1065 QRVSKQLLDSKQHNEELQ----ILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEP 1120
            Q++++Q+  ++Q  EELQ    ILV E+D  I E+KE        I   +   I + ++ 
Sbjct: 344  QKLNEQITSNQQRIEELQKNENILV-EKDKNINEIKEQLSALNQQIEGFKD--IQNKLDT 400

Query: 1121 MSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLET 1180
             +++   ++             K + EE+   +   ++  S K+   +++   K  QL+ 
Sbjct: 401  KTEEFEKLEKDFNQQ-------KSELEEKIKSKDEEIENLSKKIQDIVEQQQEKQKQLDD 453

Query: 1181 LNTELTGHDVVNQE---QINQLKSKLEQLNTENDNLLSTV-AELRSSISSAVD-QRGFEI 1235
            LN+ L   +  N++   +IN  K+K+   N + +   + + AEL+ +     D Q+ FE 
Sbjct: 454  LNSNLQNSNKENEQLKQEINDFKNKINNSNQDQEQQSNQLKAELKQTQEQLNDSQQKFEQ 513

Query: 1236 AELWKQHLAQREADFQ-------KTEHELRVQLSAFESKY---EQLLDSVQSSTQEETNK 1285
            A+   + L Q+  D +       +    L+ QL +   K    +Q L+ +Q +  +    
Sbjct: 514  ADKELKDLKQQIEDEKVKLNDKSQESENLKDQLKSANEKLNESQQKLEQIQKNFDDLKQN 573

Query: 1286 IVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXX 1345
                + V   Q K ++ E  L+ L+ +   V  Q++ L  E E+ +  F           
Sbjct: 574  NDLQKIVDEKQQKCEELERELKELKTQQEQVTAQVQQLNVEKEEIQTKFNQVEQEKEQLK 633

Query: 1346 XXXXX--DLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVL 1403
                   DL ++ +  K+  EQ I N+ +  A L+K              +++DA+  + 
Sbjct: 634  KQEQEKIDLLSQAKQEKENNEQEINNLKQTIANLEKERTDIQIQSQEKDKQLDDAKHTLE 693

Query: 1404 ELTHQLE-LKDS-----EIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKES 1457
             L  ++E LK+      ++ +K  +    +TQ   E E    ++     + E    EK+ 
Sbjct: 694  NLNKEIEQLKNQNQAIGDVNEKNKQLESEITQIKSEIEQKNTEIQSLNSKNETEISEKKQ 753

Query: 1458 ELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVA 1517
            +L     ++++       +  E+E  + ++    N+  T+   LN ++    K +EE   
Sbjct: 754  QLEDHTKQVNQLNEQIHQLSTENENLKNEIQTNQNISQTKLTDLNSEIEGFQKEIEETKL 813

Query: 1518 KTNEMQTALENQEIEIVTL-------NDEITNLQNMVRASSSK---IQK---HVSFASDT 1564
            + ++  T L+  ++++  L       N+EI  +   ++ S  K   IQK    +  +  T
Sbjct: 814  QLDDKNTQLKGLQVKLEALEKQLLEKNEEIQKVNQQLKESEQKHEAIQKQNEELQNSLKT 873

Query: 1565 KQGRD-EQLDNTMNKELLDAVPRAELDL 1591
             + +D  Q+ N +N+++ D + + E DL
Sbjct: 874  LEEKDYNQIQNDLNQQVSD-LKQKEQDL 900



 Score =  113 bits (271), Expect = 5e-23
 Identities = 171/912 (18%), Positives = 395/912 (43%), Gaps = 91/912 (9%)

Query: 147  LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNK---------ATTXXX 197
            L N +  K+N +  L  + +  +T I  L E+I    Q IE   K               
Sbjct: 318  LQNELGNKNNQIQELNEQHQKSQTEIQKLNEQITSNQQRIEELQKNENILVEKDKNINEI 377

Query: 198  XXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEAN 257
                          +D + ++    E F  +E ++  +K  L + I+SKD  I +L +  
Sbjct: 378  KEQLSALNQQIEGFKDIQNKLDTKTEEFEKLEKDFNQQKSELEEKIKSKDEEIENLSKKI 437

Query: 258  KLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLE 317
            + +   + E   +   L   L+                 K  I  S ++    +E+ S +
Sbjct: 438  QDIVEQQQEKQKQLDDLNSNLQNSNKENEQLKQEINDF-KNKINNSNQD----QEQQSNQ 492

Query: 318  IANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRN 377
            +    EL +  E L     +  Q +KEL++    +  E   ++  S++   L  +    N
Sbjct: 493  L--KAELKQTQEQLNDSQQKFEQADKELKDLKQQIEDEKVKLNDKSQESENLKDQLKSAN 550

Query: 378  TASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXX 437
               K+    SQ   E + ++ D     N++ K   ++    +   + E  + E  T    
Sbjct: 551  --EKLNE--SQQKLEQIQKNFDDLKQNNDLQK---IVDEKQQKCEELERELKELKTQ--- 600

Query: 438  XXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVN 497
                   ++ + AQ+Q   Q ++E   +          N++ + +EQLK++  ++I    
Sbjct: 601  -------QEQVTAQVQ---QLNVEKEEI------QTKFNQVEQEKEQLKKQEQEKI---- 640

Query: 498  VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDS-NKE 556
              DL+ + K  +E   Q  + +     N+ K +++ +++ ++  K +D+     ++ NKE
Sbjct: 641  --DLLSQAKQEKENNEQEINNLKQTIANLEKERTDIQIQSQEKDKQLDDAKHTLENLNKE 698

Query: 557  IVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAI 616
            I    E+L + +Q + ++ E+   L+  +        I+S++ +K  E+++L       I
Sbjct: 699  I----EQLKNQNQAIGDVNEKNKQLESEIT------QIKSEIEQKNTEIQSLNSKNETEI 748

Query: 617  SLLESQKFDLVQELHILQQKYDEVEDKLADI-SQLQSDQVCSEIKSVHLEEQIDALSASK 675
            S  + Q  D  ++++ L ++  ++  +  ++ +++Q++Q  S+ K   L  +I+      
Sbjct: 749  SEKKQQLEDHTKQVNQLNEQIHQLSTENENLKNEIQTNQNISQTKLTDLNSEIEGFQKEI 808

Query: 676  KELALVIENLKLDKEQLYGTIKDLEN---DKEDIMNKLQNYIQENMDLTDKLEKMSAEKI 732
            +E  L +++     + L   ++ LE    +K + + K+   ++E+    + ++K + E++
Sbjct: 809  EETKLQLDDKNTQLKGLQVKLEALEKQLLEKNEEIQKVNQQLKESEQKHEAIQKQN-EEL 867

Query: 733  SELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRR 792
               L  +  ++ ++IQ    ++ ++ +     +++  +L +    I ++++ ++   +  
Sbjct: 868  QNSLKTLEEKDYNQIQND--LNQQVSDLKQKEQDLNKQLDQKLQEINQIKQQLS---NET 922

Query: 793  YSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHE--NKE 850
                +K  QL   +Q+  +  S+Y  Q + +   L         ++ +L E   E  NKE
Sbjct: 923  SDFMKKNVQLQQTIQQLNQTISQYQEQIERIKTDLYQSQQEKSQLQSKLNEANREIQNKE 982

Query: 851  --LQKKNQILLE---ENQNLQISLSDMQ-QHYNALVEKANRTDLAESESTKYQTQLRDLE 904
              L KK +I+ E    N++L+I+L + + + Y+   E+ +  ++    + + Q Q +  E
Sbjct: 983  DDLNKKVEIIAELEQNNKDLKINLHNYEVKSYDLDKERFDVLEIQIQHNKEQQVQYKQAE 1042

Query: 905  SNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQL 964
              ++++  E + L+  K   +E L+ E  T  E  I ++  +++K+  N+      E Q+
Sbjct: 1043 EKIQKLEEEIKKLLADKTDSLEKLQKEIKT--EQVIGEE--MSKKFRSNL-----AELQI 1093

Query: 965  QEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEE 1024
               +N++EN    + +L ++ L  + K      T+    +  + +  +  NA      + 
Sbjct: 1094 NNEQNSLENSQKTINQLAEVVLRKV-KDCFYSSTKIVQISRLFYDGSDGRNA----SQDN 1148

Query: 1025 IIALNQKINNAQ 1036
             ++L Q++N AQ
Sbjct: 1149 ALSLIQELNEAQ 1160


>UniRef50_A2FX23 Cluster: Formin Homology 2 Domain containing protein;
            n=1; Trichomonas vaginalis G3|Rep: Formin Homology 2
            Domain containing protein - Trichomonas vaginalis G3
          Length = 2354

 Score =  172 bits (419), Expect = 6e-41
 Identities = 305/1464 (20%), Positives = 639/1464 (43%), Gaps = 159/1464 (10%)

Query: 215  KQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKL 274
            KQ   K+Q+  I  + + + EK+ + K+ E    R+ + E    + +AA    +  ++  
Sbjct: 494  KQSYKKLQDQ-IEEKTKIEGEKEEMKKENEDLKARLKTAESTIVIQKAA----AESYTSR 548

Query: 275  AQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKI-ELLEH 333
              +L+Q                ++ I+    EK  + +K    +    E ++KI E L+ 
Sbjct: 549  VNDLQQKLAEYESKLQQQISANEEKIKNQENEKVTLSQK----LKEQEEESRKIIESLQS 604

Query: 334  LNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSET 393
             +  +++ N E++  L    +  K+  + S +    + +KS  N + +  S   +L ++ 
Sbjct: 605  QSKDLQKMNNEMQVNLQNEISILKSKLTESNQKYETLEQKSS-NESDRTASALQELKTQN 663

Query: 394  LNQDTDKK---INKNEIAKLEMV----IQSLNKDLVD-----KEYVISEKDTXXXXXXXX 441
             N ++D +      NEI K   +    I+ LN D+       KE +  +++         
Sbjct: 664  KNLESDIENLTSKLNEITKQNEMKSREIERLNADIEQEKSKYKEQIDQKQNQIDQQFAML 723

Query: 442  XXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLK---QELNDEIKDVNV 498
               K  +  Q Q+  + +++   L+   T + + ++++K  E+L+   +EL +E K V  
Sbjct: 724  NDLKQQIDQQKQMNEELNIKSQRLVE--TKSSEYSDLSKQLEELQIRNKEL-EESKKVLH 780

Query: 499  KDLIEKLKSAEEQITQLNDEIDAANKNM---IKVKSNHKLKLKQMQKTIDN-FSKVSDS- 553
             DL++K +S +++  Q  ++I    KN+   ++   N K +L++  K+ +  F+++ +  
Sbjct: 781  SDLLQKQQSIKQEKEQEIEQITNQLKNVNISLENSLNEKSQLEEQLKSKETKFNELKEKL 840

Query: 554  NKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRL 613
            N  I  L EE   L +++ +L+    + +  L+   +    ES+  ++ I  +N   T+L
Sbjct: 841  NTSIENLREENETLKEEINKLQTTTADEKTTLLQSFNA---ESEPLRQKINQQNQIITKL 897

Query: 614  KAISLLESQKFDLVQELHIL---------QQKYDEVEDKLADISQLQSDQVCSEIKSV-- 662
            +  +     K +   +L +          Q++++ +  KL D  Q Q  Q+ +E KSV  
Sbjct: 898  QRENQQLQNKMEEQTQLLLTEFNNQRQNDQKEHEIIVKKLNDELQ-QKQQIYNEEKSVLE 956

Query: 663  --HLEEQIDALSASKKELALVIENLKLDKEQLY----GTIKDL----ENDKEDIMNK--- 709
                +E+ + L  SK+++  +I   + +K+QL       IK +    EN+K+ I+N    
Sbjct: 957  STFSQEKQNMLLQSKQQINQIILQNQSEKDQLTTNYENKIKSIMEQNENEKQIIINNHNI 1016

Query: 710  -LQ----NYIQENMDLTDKL--EKMSAEK-ISELLAKINHEEQS------KIQT-QFGID 754
             LQ    NY  E   L  K   +K + E+ I EL  K++ +E +      ++QT Q  ++
Sbjct: 1017 ALQTTYNNYQSEKDQLVKKFNDDKNNYEQTIKELKQKVDRQENNNKNQAYELQTAQKELE 1076

Query: 755  AKIQERDLYI-------ENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQ 807
             +I + +  +       E +   ++KYK  +   +E +   E+    L  +  +  + +Q
Sbjct: 1077 KQINKYNQVVDEANNRQEKLIGHINKYKDAVKERDEELQNRENIIDQLNNEIKKRDNLIQ 1136

Query: 808  EKQKAYSE----YTIQEDELVNRLAVLMD--HDRVVEKQLLEIE-----HENKEL-QKKN 855
             ++K Y +    Y    +EL  ++  L D  +    EK+ ++++      EN++L +KK 
Sbjct: 1137 TREKEYKQNLKAYEKTNNELNVKVQTLNDNLYQEKQEKEQIKVQMAKNNEENQKLFEKKE 1196

Query: 856  QILLEENQNLQISLSDMQQHYNALV--EKANRTDLAE--SESTKYQTQLRDLESNLKRIT 911
            Q L ++  +L +  +DM +     +  EK N  +L E  ++ +K    L+ +++NL  ++
Sbjct: 1197 QELNKKINDLMVQGTDMNEQIIKQLNSEKENSHNLQEIINKQSKELDDLKVVQNNLVSVS 1256

Query: 912  HEHQTLIVQKKK---EIEDLEIEFNTQ------IESAIRDKKV----LNEKYEKNIEYVT 958
             E++ L   K+    ++  LE +   +      +E + + K+     L+EKY+K  ++  
Sbjct: 1257 KENEGLKSDKENLTTQVNSLEQKLTNEEEKVKELEESQKQKEKEYQRLSEKYDKLKDHAI 1316

Query: 959  QLEAQLQEYKNNIENLNMNV-EELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNAL 1017
             L  QL+  +NN    N  + E++N +N E I K   +   Q+    EQ ++ I++  + 
Sbjct: 1317 NLREQLENIENNSNESNNKLNEKINLLNEE-ISKLSNENSQQNNLIQEQKVS-ISQTTSQ 1374

Query: 1018 LKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQH 1077
            LK    E  A N+ +NN    Y    +  + KL        ++ E++  ++  L +SKQ+
Sbjct: 1375 LK----EFEAKNEDLNNKCNKYEEENNTLKQKLTSEVNNSNSLSEKLSELTSLLDNSKQN 1430

Query: 1078 NEELQI----LVREQDDQIKELKETKLTFE----------MNIPKTEGMIISSTIEPMSD 1123
            ++  Q     LV   + QIK+L E KL  E          +N    +   IS+ +     
Sbjct: 1431 HQNAQSKYDELVNSSNSQIKDLTE-KLNEEKAKNDSANNKLNDLTKQNEEISAKLSHSES 1489

Query: 1124 DANNVDXXXXXXXXXXXXLKV--QEEEEFIQER----SVLQEQSAKLNTELQECYTKIIQ 1177
            + ++V             L+   Q  E  +QE+    S ++E  AK   E  E  +++++
Sbjct: 1490 ELSSVKEENNKLQSEVTTLRTTNQNNENKLQEKEKELSDVKESMAKREKEQSEVISQLMK 1549

Query: 1178 LETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAE 1237
                +++L    + + +Q+ +  ++ +++ ++    +  +  L+  +++   QR  E   
Sbjct: 1550 SADADSKLN-QAIEDLQQMQKSNAEKDKIISDQQKKIEVIVPLQLQMTNL--QREKEELN 1606

Query: 1238 LWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQE--ETNKIV-TMEQVTS 1294
               ++      +  K  +E+  +LS    +  QL D V   T E    N +V    QV +
Sbjct: 1607 ANLENTKNELKEKTKELNEVNEKLSKRSKEIVQLRDEVNQKTVEISSLNDLVHNQNQVNA 1666

Query: 1295 -LQN---KLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXX 1350
             L+N   KLQ+KEE L   Q+K  ++ +  E  +  +   +                   
Sbjct: 1667 KLENTKAKLQEKEELLEISQKKLREISSSNETFKENLNALQTE-NEQLKKENSENSENIR 1725

Query: 1351 DLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLE 1410
             L  +  +  +  E  +L +   N  L+ +              V + E ++  L + + 
Sbjct: 1726 KLNEQISTINRQNEDKLLELKHNNDALQNTIQNVTSKNSQLEADVQNKEKELQRLNNLVT 1785

Query: 1411 LKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENA 1470
                E+  K ++      Q+N    +  Q++ + ++ I  L    E  +     K+ E+ 
Sbjct: 1786 EISGELKSKENKAEDQKQQQNSILSSKEQEIKQLKEEINQLNSNSEKLVQNYNSKLEES- 1844

Query: 1471 NHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQE 1530
               E    +  ++  + +  LN K+ +  S NK++++   +LEE+  KTN +    E  +
Sbjct: 1845 ---EKKINKLNLKHGEEVTSLNTKLQQISSENKKISQEKTSLEED--KTN-LSKENEEYK 1898

Query: 1531 IEIVTLNDEITNLQNMVRASSSKI 1554
             ++  L  ++  L N +     +I
Sbjct: 1899 SQLQDLKKKLEELNNTISDKEKEI 1922



 Score =  169 bits (410), Expect = 7e-40
 Identities = 245/1190 (20%), Positives = 528/1190 (44%), Gaps = 116/1190 (9%)

Query: 454  LEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQIT 513
            +E Q+  E      + TN E       V+E+L++++    K+  ++ + +  K  ++QI 
Sbjct: 448  IESQKPSESDDDGKILTNKEAKKMFEDVREKLEEQIRT--KEDELRAIKQSYKKLQDQIE 505

Query: 514  QLNDEIDAANKNMIKVKSNHKLKLKQMQKTI-------DNF-SKVSDSNKEIV----RLT 561
            +   +I+   + M K   + K +LK  + TI       +++ S+V+D  +++     +L 
Sbjct: 506  E-KTKIEGEKEEMKKENEDLKARLKTAESTIVIQKAAAESYTSRVNDLQQKLAEYESKLQ 564

Query: 562  EELHHLSQKVAELEEEKGNLQLHLVDYD--SGRMIES--DVYKKMIEMENLAETRLK-AI 616
            +++    +K+   E EK  L   L + +  S ++IES     K + +M N  +  L+  I
Sbjct: 565  QQISANEEKIKNQENEKVTLSQKLKEQEEESRKIIESLQSQSKDLQKMNNEMQVNLQNEI 624

Query: 617  SLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKK 676
            S+L+S+  +  Q+   L+QK     D+ A  S LQ      + ++ +LE  I+ L++   
Sbjct: 625  SILKSKLTESNQKYETLEQKSSNESDRTA--SALQE----LKTQNKNLESDIENLTSKLN 678

Query: 677  ELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELL 736
            E+    E    + E+L   I+  ++  ++ +++ QN I +   + + L K   ++  ++ 
Sbjct: 679  EITKQNEMKSREIERLNADIEQEKSKYKEQIDQKQNQIDQQFAMLNDL-KQQIDQQKQMN 737

Query: 737  AKINHEEQSKIQTQFG--IDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYS 794
             ++N + Q  ++T+     D   Q  +L I N E E SK       L++  ++ +++   
Sbjct: 738  EELNIKSQRLVETKSSEYSDLSKQLEELQIRNKELEESKKVLHSDLLQKQQSIKQEKEQE 797

Query: 795  LERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKK 854
            +E+  +QL +     + + +E +  E++L ++       + + EK    IE+    L+++
Sbjct: 798  IEQITNQLKNVNISLENSLNEKSQLEEQLKSKETKF---NELKEKLNTSIEN----LREE 850

Query: 855  NQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEH 914
            N+ L EE   LQ + +D         EK        +ES   + ++      + ++  E+
Sbjct: 851  NETLKEEINKLQTTTAD---------EKTTLLQSFNAESEPLRQKINQQNQIITKLQREN 901

Query: 915  QTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIEN- 973
            Q L  + +++ + L  EFN Q ++  ++ +++ +K    ++   Q+     E K+ +E+ 
Sbjct: 902  QQLQNKMEEQTQLLLTEFNNQRQNDQKEHEIIVKKLNDELQQKQQI---YNEEKSVLEST 958

Query: 974  LNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKIN 1033
             +   + +   + + I++ + + Q++    T  Y N+I  +  + + ++E+ I +N    
Sbjct: 959  FSQEKQNMLLQSKQQINQIILQNQSEKDQLTTNYENKIKSI--MEQNENEKQIIINNHNI 1016

Query: 1034 NAQVSYMSMVSDYESKLAQFTTKLENMEEEM----QRVSKQLLDSKQHNEELQILVREQD 1089
              Q +Y +  S+ +  + +F     N E+ +    Q+V +Q  ++K    ELQ   +E +
Sbjct: 1017 ALQTTYNNYQSEKDQLVKKFNDDKNNYEQTIKELKQKVDRQENNNKNQAYELQTAQKELE 1076

Query: 1090 DQIKELKETKLTFEMNIPKTEGMI------ISSTIEPMSDDANNVDXXXXXXXXXXXXLK 1143
             QI +  +          K  G I      +    E + +  N +D            ++
Sbjct: 1077 KQINKYNQVVDEANNRQEKLIGHINKYKDAVKERDEELQNRENIIDQLNNEIKKRDNLIQ 1136

Query: 1144 VQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKL 1203
             +E+E + Q     ++ + +LN ++Q     + Q +    ++      N E+  +L  K 
Sbjct: 1137 TREKE-YKQNLKAYEKTNNELNVKVQTLNDNLYQEKQEKEQIKVQMAKNNEENQKLFEKK 1195

Query: 1204 EQ-LNTENDNLLSTVAELRSSISSAVD---QRGFEIAELWKQHLAQREADFQKTEHELRV 1259
            EQ LN + ++L+    ++   I   ++   +    + E+  +    +E D  K      V
Sbjct: 1196 EQELNKKINDLMVQGTDMNEQIIKQLNSEKENSHNLQEIINKQ--SKELDDLKVVQNNLV 1253

Query: 1260 QLS----AFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYAD 1315
             +S      +S  E L   V S  Q+ TN+    E+V  L+   + KE+  + L EKY  
Sbjct: 1254 SVSKENEGLKSDKENLTTQVNSLEQKLTNE---EEKVKELEESQKQKEKEYQRLSEKYDK 1310

Query: 1316 VINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENA 1375
            + +    LR ++E+ +                        N+S  ++ E+  L +NEE +
Sbjct: 1311 LKDHAINLREQLENIE---------------------NNSNESNNKLNEKINL-LNEEIS 1348

Query: 1376 QLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFE 1435
            +L   +             ++   +++ E     E K+ ++  K ++Y        +E  
Sbjct: 1349 KLSNENSQQNNLIQEQKVSISQTTSQLKEF----EAKNEDLNNKCNKY-------EEENN 1397

Query: 1436 NVRQQLVEYEKRIEDLTYEKESELAIL---RLKMHENA-NHYETMQKESEIERVKLIEEL 1491
             ++Q+L         L+ EK SEL  L     + H+NA + Y+ +   S  +   L E+L
Sbjct: 1398 TLKQKLTSEVNNSNSLS-EKLSELTSLLDNSKQNHQNAQSKYDELVNSSNSQIKDLTEKL 1456

Query: 1492 NVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASS 1551
            N +  ++ S N ++ +L K  EE  AK +  ++ L + + E   L  E+T L+   + + 
Sbjct: 1457 NEEKAKNDSANNKLNDLTKQNEEISAKLSHSESELSSVKEENNKLQSEVTTLRTTNQNNE 1516

Query: 1552 SKIQKHVSFASDTKQG---RDEQLDNTMNKELLDAVPRAELDLAMYMLHQ 1598
            +K+Q+     SD K+    R+++    +++ +  A   ++L+ A+  L Q
Sbjct: 1517 NKLQEKEKELSDVKESMAKREKEQSEVISQLMKSADADSKLNQAIEDLQQ 1566



 Score =  156 bits (378), Expect = 5e-36
 Identities = 280/1424 (19%), Positives = 602/1424 (42%), Gaps = 129/1424 (9%)

Query: 230  AEWKDEKQRLLKDIESKDV-RISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXX 288
            A++ D      K  ES D  +I + +EA K+ E  R +  LE     +E E         
Sbjct: 441  AKYLDSSIESQKPSESDDDGKILTNKEAKKMFEDVREK--LEEQIRTKEDELRAIKQSYK 498

Query: 289  XXXXXXLAKQSIEPSCEE-KTEIEE-KGSLEIANMTELTKKIELLEHLNC--QIRQTNKE 344
                    K  IE   EE K E E+ K  L+ A  T + +K     + +    ++Q   E
Sbjct: 499  KLQDQIEEKTKIEGEKEEMKKENEDLKARLKTAESTIVIQKAAAESYTSRVNDLQQKLAE 558

Query: 345  LENKLATM--GTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKI 402
             E+KL       E K  +  ++K +     K     + K+       S +    + + ++
Sbjct: 559  YESKLQQQISANEEKIKNQENEKVTLSQKLKEQEEESRKIIESLQSQSKDLQKMNNEMQV 618

Query: 403  N-KNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHME 461
            N +NEI+ L+  +   N+    K   + +K +               + +L+ +++ ++E
Sbjct: 619  NLQNEISILKSKLTESNQ----KYETLEQKSSNESDRTASA------LQELKTQNK-NLE 667

Query: 462  GPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDA 521
                  +   T  +NEI K Q ++K     EI+ +N  D+ ++    +EQI Q  ++ID 
Sbjct: 668  SD----IENLTSKLNEITK-QNEMKSR---EIERLNA-DIEQEKSKYKEQIDQKQNQIDQ 718

Query: 522  --ANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKG 579
              A  N +K + + + ++ + +  I +   V   + E   L+++L  L  +  ELEE K 
Sbjct: 719  QFAMLNDLKQQIDQQKQMNE-ELNIKSQRLVETKSSEYSDLSKQLEELQIRNKELEESKK 777

Query: 580  NLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDE 639
             L   L+       I+ +  +++ ++ N  +    ++    ++K  L ++L   + K++E
Sbjct: 778  VLHSDLLQKQQS--IKQEKEQEIEQITNQLKNVNISLENSLNEKSQLEEQLKSKETKFNE 835

Query: 640  VEDKL-ADISQLQSD-----QVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLY 693
            +++KL   I  L+ +     +  +++++   +E+   L +   E     E L+    Q  
Sbjct: 836  LKEKLNTSIENLREENETLKEEINKLQTTTADEKTTLLQSFNAES----EPLRQKINQQN 891

Query: 694  GTIKDLENDKEDIMNKLQNYIQ------ENMDLTDKLE-KMSAEKISELLAK---INHEE 743
              I  L+ + + + NK++   Q       N    D+ E ++  +K+++ L +   I +EE
Sbjct: 892  QIITKLQRENQQLQNKMEEQTQLLLTEFNNQRQNDQKEHEIIVKKLNDELQQKQQIYNEE 951

Query: 744  QSKIQTQFGIDAK---IQERDLYIENIESELSKYKSRICRLEESI-AVMEDRRYSLERKA 799
            +S +++ F  + +   +Q +    + I    S+        E  I ++ME        K 
Sbjct: 952  KSVLESTFSQEKQNMLLQSKQQINQIILQNQSEKDQLTTNYENKIKSIMEQNE---NEKQ 1008

Query: 800  DQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILL 859
              + ++    Q  Y+ Y  ++D+LV +     D     E+ + E++ +    +  N+   
Sbjct: 1009 IIINNHNIALQTTYNNYQSEKDQLVKKFN---DDKNNYEQTIKELKQKVDRQENNNKNQA 1065

Query: 860  EENQNLQISLSDMQQHYNALVEKAN-RTDLAESESTKYQTQLRDLESNLKR---ITHEHQ 915
             E Q  Q  L      YN +V++AN R +       KY+  +++ +  L+    I  +  
Sbjct: 1066 YELQTAQKELEKQINKYNQVVDEANNRQEKLIGHINKYKDAVKERDEELQNRENIIDQLN 1125

Query: 916  TLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLN 975
              I ++   I+  E E+   +++  +    LN K +   + + Q + + ++ K  +   N
Sbjct: 1126 NEIKKRDNLIQTREKEYKQNLKAYEKTNNELNVKVQTLNDNLYQEKQEKEQIKVQMAKNN 1185

Query: 976  MNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNA 1035
               ++L +   + ++K +     Q  D  EQ I ++N      K+    +    Q+I N 
Sbjct: 1186 EENQKLFEKKEQELNKKINDLMVQGTDMNEQIIKQLNSE----KENSHNL----QEIINK 1237

Query: 1036 QVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQL--LDSKQHNEELQILVREQDDQIK 1093
            Q   +  +   ++ L   + + E ++ + + ++ Q+  L+ K  NEE ++   E+  + K
Sbjct: 1238 QSKELDDLKVVQNNLVSVSKENEGLKSDKENLTTQVNSLEQKLTNEEEKVKELEESQKQK 1297

Query: 1094 ELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQE 1153
            E +  +L+ + +  K   + +   +E + +++N  +               +   E  Q+
Sbjct: 1298 EKEYQRLSEKYDKLKDHAINLREQLENIENNSNESNNKLNEKINLLNEEISKLSNENSQQ 1357

Query: 1154 RSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQ----------EQINQLKSKL 1203
             +++QEQ   ++    +      + E LN +   ++  N              N L  KL
Sbjct: 1358 NNLIQEQKVSISQTTSQLKEFEAKNEDLNNKCNKYEEENNTLKQKLTSEVNNSNSLSEKL 1417

Query: 1204 EQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSA 1263
             +L +  DN        +S     V+    +I +L ++ L + +A      ++L      
Sbjct: 1418 SELTSLLDNSKQNHQNAQSKYDELVNSSNSQIKDLTEK-LNEEKAKNDSANNKLNDLTKQ 1476

Query: 1264 FESKYEQLL--DSVQSSTQEETNKI---VTMEQVTSL--QNKLQDKEEHLRNLQEKYA-- 1314
             E    +L   +S  SS +EE NK+   VT  + T+   +NKLQ+KE+ L +++E  A  
Sbjct: 1477 NEEISAKLSHSESELSSVKEENNKLQSEVTTLRTTNQNNENKLQEKEKELSDVKESMAKR 1536

Query: 1315 -----DVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQM---QEQS 1366
                 +VI+Q+  ++S   D K+                   + ++ Q   ++    +  
Sbjct: 1537 EKEQSEVISQL--MKSADADSKLNQAIEDLQQMQKSNAEKDKIISDQQKKIEVIVPLQLQ 1594

Query: 1367 ILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTI- 1425
            + N+  E  +L  +              +N+   K+ + + ++     E+ QKT E +  
Sbjct: 1595 MTNLQREKEELNANLENTKNELKEKTKELNEVNEKLSKRSKEIVQLRDEVNQKTVEISSL 1654

Query: 1426 -----TLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKES 1480
                    Q N + EN + +L E E+ +E ++ +K  E++       EN N  +T  ++ 
Sbjct: 1655 NDLVHNQNQVNAKLENTKAKLQEKEELLE-ISQKKLREISSSNETFKENLNALQTENEQL 1713

Query: 1481 EIERVKLIEELNVKITESVS-LNKQ----VAEL---NKALEEEV----AKTNEMQTALEN 1528
            + E  +  E +  K+ E +S +N+Q    + EL   N AL+  +    +K ++++  ++N
Sbjct: 1714 KKENSENSENIR-KLNEQISTINRQNEDKLLELKHNNDALQNTIQNVTSKNSQLEADVQN 1772

Query: 1529 QEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQL 1572
            +E E+  LN+ +T +   +++  +K +      +     +++++
Sbjct: 1773 KEKELQRLNNLVTEISGELKSKENKAEDQKQQQNSILSSKEQEI 1816



 Score =  149 bits (360), Expect = 8e-34
 Identities = 265/1412 (18%), Positives = 572/1412 (40%), Gaps = 118/1412 (8%)

Query: 101  KEILMEKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKE--KDNAL 158
            K  L E  ++Y+ L ++SS    R               +  D+ +L++ + E  K N  
Sbjct: 628  KSKLTESNQKYETLEQKSSNESDRTASALQELKTQNKNLE-SDIENLTSKLNEITKQN-- 684

Query: 159  SVLQVKMKIMETTILDL-QEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQ 217
               ++K + +E    D+ QEK   K+QI + +N+                     + +  
Sbjct: 685  ---EMKSREIERLNADIEQEKSKYKEQIDQKQNQIDQQFAMLNDLKQQIDQQKQMNEELN 741

Query: 218  MTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQE 277
            + K Q       +E+ D    L K +E   +R   LEE+ K+L +   ++  +   + QE
Sbjct: 742  I-KSQRLVETKSSEYSD----LSKQLEELQIRNKELEESKKVLHS---DLLQKQQSIKQE 793

Query: 278  LEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIEL-LEHLNC 336
             EQ                  S+E S  EK+++EE+   +     EL +K+   +E+L  
Sbjct: 794  KEQEIEQITNQLKNVNI----SLENSLNEKSQLEEQLKSKETKFNELKEKLNTSIENLR- 848

Query: 337  QIRQTNKELENKLATMGTESKA--VSSPSKKGSPLISRKSGRNTA-SKMKSPWSQLSSET 393
            +  +T KE  NKL T   + K   + S + +  PL  + + +N   +K++    QL ++ 
Sbjct: 849  EENETLKEEINKLQTTTADEKTTLLQSFNAESEPLRQKINQQNQIITKLQRENQQLQNKM 908

Query: 394  LNQD----TD-KKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTL 448
              Q     T+     +N+  + E++++ LN +L  K+ + +E+ +              L
Sbjct: 909  EEQTQLLLTEFNNQRQNDQKEHEIIVKKLNDELQQKQQIYNEEKSVLESTFSQEKQNMLL 968

Query: 449  IAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSA 508
             ++ Q+             + TN E  N+I  + EQ + E    I + N+        + 
Sbjct: 969  QSKQQINQIILQNQSEKDQLTTNYE--NKIKSIMEQNENEKQIIINNHNI--------AL 1018

Query: 509  EEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNK-EIVRLTEELHHL 567
            +        E D   K     K+N++  +K++++ +D     + +   E+    +EL   
Sbjct: 1019 QTTYNNYQSEKDQLVKKFNDDKNNYEQTIKELKQKVDRQENNNKNQAYELQTAQKELEKQ 1078

Query: 568  SQKVAELEEEKGNLQLHLVDY-----DSGRMIESDVYKKMIEMENLAETRLKAISLLESQ 622
              K  ++ +E  N Q  L+ +     D+ +  + ++  +   ++ L     K  +L++++
Sbjct: 1079 INKYNQVVDEANNRQEKLIGHINKYKDAVKERDEELQNRENIIDQLNNEIKKRDNLIQTR 1138

Query: 623  KFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVI 682
            + +  Q L   ++  +E+  K+    Q  +D +  E +    +EQI    A   E     
Sbjct: 1139 EKEYKQNLKAYEKTNNELNVKV----QTLNDNLYQEKQE---KEQIKVQMAKNNE----- 1186

Query: 683  ENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKM--SAEKISELLAKIN 740
            EN KL            E  ++++  K+ + + +  D+ +++ K   S ++ S  L +I 
Sbjct: 1187 ENQKL-----------FEKKEQELNKKINDLMVQGTDMNEQIIKQLNSEKENSHNLQEII 1235

Query: 741  HEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKAD 800
            +++  ++      D K+ + +L   ++  E    KS    L   +  +E +  + E K  
Sbjct: 1236 NKQSKELD-----DLKVVQNNLV--SVSKENEGLKSDKENLTTQVNSLEQKLTNEEEKVK 1288

Query: 801  QLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKK-NQILL 859
            +L    ++K+K Y   + + D+L        DH   + +QL  IE+ + E   K N+ + 
Sbjct: 1289 ELEESQKQKEKEYQRLSEKYDKL-------KDHAINLREQLENIENNSNESNNKLNEKIN 1341

Query: 860  EENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIV 919
              N+ +    ++  Q  N + E+        S+  +++ +  DL +   +   E+ TL  
Sbjct: 1342 LLNEEISKLSNENSQQNNLIQEQKVSISQTTSQLKEFEAKNEDLNNKCNKYEEENNTLKQ 1401

Query: 920  QKKKEIEDLEI--EFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMN 977
            +   E+ +     E  +++ S + + K  ++  +   +Y   + +   + K+  E LN  
Sbjct: 1402 KLTSEVNNSNSLSEKLSELTSLLDNSKQNHQNAQS--KYDELVNSSNSQIKDLTEKLNEE 1459

Query: 978  VEELNKMNLELIDKHVQKQQTQSP-DYTEQYINEINKLNALLKQKDEEIIALNQKINNAQ 1036
              + +  N +L D   Q ++  +   ++E  ++ + + N  L+ +   +   NQ   N  
Sbjct: 1460 KAKNDSANNKLNDLTKQNEEISAKLSHSESELSSVKEENNKLQSEVTTLRTTNQNNENK- 1518

Query: 1037 VSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELK 1096
                  + + E +L+     +   E+E   V  QL+ S   + +L   + +     K   
Sbjct: 1519 ------LQEKEKELSDVKESMAKREKEQSEVISQLMKSADADSKLNQAIEDLQQMQKSNA 1572

Query: 1097 ETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSV 1156
            E          K E       I P+     N+              K  E +E  +E + 
Sbjct: 1573 EKDKIISDQQKKIE------VIVPLQLQMTNLQREKEELNANLENTK-NELKEKTKELNE 1625

Query: 1157 LQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQIN-QLKSKLEQLNTENDNLLS 1215
            + E+ +K + E+ +   ++ Q +T+        V NQ Q+N +L++   +L  + + L  
Sbjct: 1626 VNEKLSKRSKEIVQLRDEVNQ-KTVEISSLNDLVHNQNQVNAKLENTKAKLQEKEELLEI 1684

Query: 1216 TVAELRS-SISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDS 1274
            +  +LR  S S+   +      +   + L +  ++  +   +L  Q+S    + E  L  
Sbjct: 1685 SQKKLREISSSNETFKENLNALQTENEQLKKENSENSENIRKLNEQISTINRQNEDKLLE 1744

Query: 1275 VQSSTQEETNKIVTMEQVTS-LQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVA 1333
            ++ +     N I  +    S L+  +Q+KE+ L+ L     ++  +++   ++ ED+K  
Sbjct: 1745 LKHNNDALQNTIQNVTSKNSQLEADVQNKEKELQRLNNLVTEISGELKSKENKAEDQK-- 1802

Query: 1334 FXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXX 1393
                             +++   +   Q+   S   +   N++L++S             
Sbjct: 1803 -----QQQNSILSSKEQEIKQLKEEINQLNSNSEKLVQNYNSKLEESEKKINKLNLKHGE 1857

Query: 1394 RVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTY 1453
             V     K+ +++ + + K S+      E    L++ N+E+++  Q L +  + + +   
Sbjct: 1858 EVTSLNTKLQQISSENK-KISQEKTSLEEDKTNLSKENEEYKSQLQDLKKKLEELNNTIS 1916

Query: 1454 EKESELAILRLKMHENANHYETMQKESEIERV 1485
            +KE E+  L+L + E      T +   E E V
Sbjct: 1917 DKEKEINDLKLHVVETTEEKGTQEVAEEEEEV 1948



 Score =  124 bits (300), Expect = 2e-26
 Identities = 167/876 (19%), Positives = 382/876 (43%), Gaps = 61/876 (6%)

Query: 309  EIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSP 368
            EI+++ +L      E  + ++  E  N ++    + L + L     E + +     K + 
Sbjct: 1127 EIKKRDNLIQTREKEYKQNLKAYEKTNNELNVKVQTLNDNLYQEKQEKEQIKVQMAKNNE 1186

Query: 369  LISRKSGRNTASKMKSPWSQLSSE--TLNQDTDKKIN--KNEIAKLEMVIQSLNKDLVDK 424
              ++K       ++    + L  +   +N+   K++N  K     L+ +I   +K+L D 
Sbjct: 1187 E-NQKLFEKKEQELNKKINDLMVQGTDMNEQIIKQLNSEKENSHNLQEIINKQSKELDDL 1245

Query: 425  EYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQ 484
            + V +   +           K+ L  Q+    Q+      L +     +++ E  K +E+
Sbjct: 1246 KVVQNNLVSVSKENEGLKSDKENLTTQVNSLEQK------LTNEEEKVKELEESQKQKEK 1299

Query: 485  LKQELN---DEIKD--VNVKDLIEKLKS-AEEQITQLNDEIDAANKNMIKVKSNHKLKLK 538
              Q L+   D++KD  +N+++ +E +++ + E   +LN++I+  N+ + K+ + +  +  
Sbjct: 1300 EYQRLSEKYDKLKDHAINLREQLENIENNSNESNNKLNEKINLLNEEISKLSNENSQQNN 1359

Query: 539  QMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDV 598
             +Q+   + S+ +   KE     E+L++   K  + EEE   L+  L    +     + +
Sbjct: 1360 LIQEQKVSISQTTSQLKEFEAKNEDLNN---KCNKYEEENNTLKQKLTSEVNN---SNSL 1413

Query: 599  YKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSE 658
             +K+ E+ +L +   +     +S K+D      ++     +++D    +++ ++    + 
Sbjct: 1414 SEKLSELTSLLDNSKQNHQNAQS-KYD-----ELVNSSNSQIKDLTEKLNEEKAKNDSAN 1467

Query: 659  IKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENM 718
             K   L +Q + +SA        + ++K +  +L   +  L    ++  NKLQ   +E  
Sbjct: 1468 NKLNDLTKQNEEISAKLSHSESELSSVKEENNKLQSEVTTLRTTNQNNENKLQEKEKELS 1527

Query: 719  DLTDKLEKMSAEKISELLAKI--NHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKS 776
            D+ + + K   E+ SE+++++  + +  SK+        ++Q+ +   + I S+  K   
Sbjct: 1528 DVKESMAKREKEQ-SEVISQLMKSADADSKLNQAIEDLQQMQKSNAEKDKIISDQQKKIE 1586

Query: 777  RICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRV 836
             I  L+  +  ++  +  L    +   + L+EK K  +E   +  +    +  L D    
Sbjct: 1587 VIVPLQLQMTNLQREKEELNANLENTKNELKEKTKELNEVNEKLSKRSKEIVQLRDE--- 1643

Query: 837  VEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKY 896
            V ++ +EI   N  +  +NQ+    N  L+ + + +Q+    L     +     S +  +
Sbjct: 1644 VNQKTVEISSLNDLVHNQNQV----NAKLENTKAKLQEKEELLEISQKKLREISSSNETF 1699

Query: 897  QTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEY 956
            +  L  L++  +++  E+       +K  E +    N Q E  + + K  N+  +  I+ 
Sbjct: 1700 KENLNALQTENEQLKKENSENSENIRKLNEQIST-INRQNEDKLLELKHNNDALQNTIQN 1758

Query: 957  VTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNA 1016
            VT   +QL+    +++N    ++ LN +  E I   ++ ++ ++ D  +Q        N+
Sbjct: 1759 VTSKNSQLEA---DVQNKEKELQRLNNLVTE-ISGELKSKENKAEDQKQQQ-------NS 1807

Query: 1017 LLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENME----EEMQRVSKQL- 1071
            +L  K++EI  L ++IN    +   +V +Y SKL +   K+  +     EE+  ++ +L 
Sbjct: 1808 ILSSKEQEIKQLKEEINQLNSNSEKLVQNYNSKLEESEKKINKLNLKHGEEVTSLNTKLQ 1867

Query: 1072 ---LDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNV 1128
                ++K+ ++E   L  ++ +  KE +E K   +    K E   +++TI     + N++
Sbjct: 1868 QISSENKKISQEKTSLEEDKTNLSKENEEYKSQLQDLKKKLEE--LNNTISDKEKEINDL 1925

Query: 1129 DXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKL 1164
                          +V EEEE + E + L+  S  L
Sbjct: 1926 KLHVVETTEEKGTQEVAEEEEEVGEMAPLKPVSNNL 1961



 Score = 81.0 bits (191), Expect = 2e-13
 Identities = 125/584 (21%), Positives = 230/584 (39%), Gaps = 49/584 (8%)

Query: 90   ISESLANTLKQKEILMEKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSN 149
            + + L + +     L EK+ +   L   S     +               Q+ D+T   N
Sbjct: 1399 LKQKLTSEVNNSNSLSEKLSELTSLLDNSKQNH-QNAQSKYDELVNSSNSQIKDLTEKLN 1457

Query: 150  TIKEK-DNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXX 208
              K K D+A + L    K  E     L    +E   + E  NK  +              
Sbjct: 1458 EEKAKNDSANNKLNDLTKQNEEISAKLSHSESELSSVKEENNKLQSEVTTLRTTNQNNEN 1517

Query: 209  XXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLK--DIESK-DVRISSLEEANKLLEAARF 265
               E  K+ ++ ++E+    E E  +   +L+K  D +SK +  I  L++  K   A + 
Sbjct: 1518 KLQEKEKE-LSDVKESMAKREKEQSEVISQLMKSADADSKLNQAIEDLQQMQKS-NAEKD 1575

Query: 266  EISLEHSKLAQELEQXXXXXXXXXXXXXXL------AKQSIEPSCEEKTEIEEK---GSL 316
            +I  +  K  + +                L       K  ++   +E  E+ EK    S 
Sbjct: 1576 KIISDQQKKIEVIVPLQLQMTNLQREKEELNANLENTKNELKEKTKELNEVNEKLSKRSK 1635

Query: 317  EIANMT-ELTKKIELLEHLNCQIR---QTNKELENKLATMGTESKAVSSPSKKGSPLISR 372
            EI  +  E+ +K   +  LN  +    Q N +LEN  A +  + + +    KK    +  
Sbjct: 1636 EIVQLRDEVNQKTVEISSLNDLVHNQNQVNAKLENTKAKLQEKEELLEISQKK----LRE 1691

Query: 373  KSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKD 432
             S  N   K      Q  +E L ++  +  N   I KL   I ++N+   DK   +   +
Sbjct: 1692 ISSSNETFKENLNALQTENEQLKKENSE--NSENIRKLNEQISTINRQNEDKLLELKHNN 1749

Query: 433  TXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDE 492
                        K++     QLE     +   L  +       N + ++  +LK + N  
Sbjct: 1750 DALQNTIQNVTSKNS-----QLEADVQNKEKELQRLN------NLVTEISGELKSKENKA 1798

Query: 493  IKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFS---- 548
                  ++ I  L S E++I QL +EI+  N N  K+  N+  KL++ +K I+  +    
Sbjct: 1799 EDQKQQQNSI--LSSKEQEIKQLKEEINQLNSNSEKLVQNYNSKLEESEKKINKLNLKHG 1856

Query: 549  -KVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMEN 607
             +V+  N ++ +++ E   +SQ+   LEE+K NL     +Y S      D+ KK+ E+ N
Sbjct: 1857 EEVTSLNTKLQQISSENKKISQEKTSLEEDKTNLSKENEEYKSQL---QDLKKKLEELNN 1913

Query: 608  LAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQ 651
                + K I+ L+    +  +E     Q+  E E+++ +++ L+
Sbjct: 1914 TISDKEKEINDLKLHVVETTEEKG--TQEVAEEEEEVGEMAPLK 1955


>UniRef50_A0CWJ6 Cluster: Chromosome undetermined scaffold_3, whole
            genome shotgun sequence; n=2; Paramecium tetraurelia|Rep:
            Chromosome undetermined scaffold_3, whole genome shotgun
            sequence - Paramecium tetraurelia
          Length = 1259

 Score =  172 bits (419), Expect = 6e-41
 Identities = 250/1122 (22%), Positives = 518/1122 (46%), Gaps = 94/1122 (8%)

Query: 477  EIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKS----- 531
            E+A  Q+  ++EL  EI     KD I+K+K  EEQ  QL  E+D   K +I+ +      
Sbjct: 114  ELANYQQHFEEELQLEITQ---KDYIDKIKGLEEQNQQLIHELDLVTKKLIESQRGSLNN 170

Query: 532  -NHKLKLKQMQKTIDNF-SKVSDSNKEIVRLTEELHHLSQK-----VAELEEEKGNLQLH 584
             ++  + +Q ++ I++   K+   +K + +  EEL   + K     + +L+ EK    L 
Sbjct: 171  YDNNYQTQQYEQIIEDLQQKIEQLSKFLSQKDEELQQNNNKQYLVQIEQLQIEKITQSLQ 230

Query: 585  LVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKL 644
            L +Y +     + + ++  E  N+ + +LK    L S + +++Q+ +++Q K+  ++   
Sbjct: 231  LEEYKNK---INKLQQEQEEKNNIID-QLKKNYSLNSSRNEIIQKQNMIQNKHQYIKID- 285

Query: 645  ADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKE 704
             ++ +L  D   +  +  + + Q    + S K     +E  K  + Q       L    E
Sbjct: 286  QNVLELSDDIETTVKRRTNFDYQAGKYNQSGKGF---LEQ-KSPRSQFSDQDSYLFL-CE 340

Query: 705  DIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYI 764
             +   LQ   ++  DL +K +    E    L+  I   E S  + Q  I+ +  E     
Sbjct: 341  KLQQDLQTEEKQYNDLANKKQMADIEN-DRLINLIKELEYSIQEKQLLIEHQDNEIKSNQ 399

Query: 765  ENIESELSKYKSRICRLEESIAVMEDRRYSLER-KADQLGSYLQEKQKAYSEYTIQEDEL 823
             NI  + S++K  I + ++ + + ED+  +LE  + ++L  Y Q+  +  S+   Q+D  
Sbjct: 400  RNIRKKESEHKKTIIQQQDDMQIYEDKLNALENLRKEELRIYEQQISQIQSQLK-QKDIE 458

Query: 824  VNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNA--LVE 881
            + +L         ++ ++  +  ENKE+Q+  QI  ++ ++L+  ++ +QQ      L +
Sbjct: 459  LKKLQDQTKDKHKLQAKIQSLIEENKEIQQNIQIKDQKEEDLKTKVALLQQQLKTKELDK 518

Query: 882  KANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKE---IEDLEI-EFNTQI- 936
              N   + + ES   Q +L +LE N+  I  + QT I QK ++   +++ +I +   Q+ 
Sbjct: 519  SQNSNRIYDLESQIIQLKL-ELEQNI--INAQLQTEINQKNEQQMKLKEFQINKLQDQLK 575

Query: 937  ESAIRDKKVLNEKYEKNIEYVTQLEAQ---LQEYKNNIENL-NMNVEELNKMNLELIDKH 992
            E++ + K+++ E+  +N     Q++ Q   L++ +  I+ L N+  +   + NL +  ++
Sbjct: 576  EASNKQKEIITERELENQRNYQQIDEQNDLLRKQEYEIKRLQNLISQRPLEKNLNIQSEN 635

Query: 993  -VQKQQTQSPDYTEQYINE-INKLNALLKQKDEEIIALNQK--INNAQVSYMSMVSDYES 1048
             V K+Q +     E  + + +  L   LK KD+EII  +QK  ++NA++      ++ + 
Sbjct: 636  LVLKEQIEELLNQEANLEQKVIILETQLKGKDQEIIVTSQKQILSNAELQ-----TNMKK 690

Query: 1049 KLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPK 1108
            + A F  KL   E+++Q++ K+     Q NE+L   ++  D +  +L E K   E+   +
Sbjct: 691  QEADFNDKLIEKEQQIQKLIKENQSLNQENEQLLHKIKNHDSRNAQL-EMKEQQELESHR 749

Query: 1109 TEGMIISSTIE--PMSDDANNVDXXXX----XXXXXXXXLKVQEEEEFIQERSVLQEQSA 1162
             E   I   I+  P+SDD   +                 L+ Q +++ IQ  +VL +Q  
Sbjct: 750  LE---IQKKIDQIPLSDDGTTLSELNSYRMDELKTFASQLESQNKKDLIQ--TVL-DQKI 803

Query: 1163 KLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRS 1222
            ++  +  +   ++  +E L +++  ++   ++Q   ++SK +QL  E ++   +++ L +
Sbjct: 804  EMVQKNDQLNNQVQIIEELKSKIKMNEEELKDQRELVESKQKQL-AELNSFKQSISSLEN 862

Query: 1223 SISSAVDQRGFEIAELWKQHLAQREADF--QKTEHELRVQLSAFESKYEQLLDSVQSSTQ 1280
             +   V ++  + A+   + L Q++     QK ++E + Q    ESK  +L D +Q+  Q
Sbjct: 863  QLK--VKEQSLKKAQEENKELQQQKQIVIQQKKQNETQQQ----ESK--KLQDVIQNQEQ 914

Query: 1281 EETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXX 1340
            +   K   ++       KLQD+   L    E+ +  +NQ ++L+ E+E  K A       
Sbjct: 915  QMKTKDENLK-------KLQDQLRELGKKNEQLSKDLNQNKVLKDEVEKYKNALNQKEEE 967

Query: 1341 XXXXXXXXXXDLRTENQSYK-QMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAE 1399
                        + ++Q  K Q Q +      +E  +  ++             ++N  +
Sbjct: 968  QKNLQNQISNQKKQDDQIKKLQQQLEKETKTKKEEIEKLQNEINELNQELQQAQQLNYNQ 1027

Query: 1400 AKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRI---EDLTYEKE 1456
             K   L  Q++    ++ Q+T +    L     + +N++ QL E  +++   E+    KE
Sbjct: 1028 KK---LEDQVKKLQQQLDQQTEKSKKQLQDSEKKQQNLQNQLKETAEQLSEWEENDLTKE 1084

Query: 1457 SELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEV 1516
             ++  L  ++ E     E  QK+   + VK ++E  +K  E V++  Q  + N   E+  
Sbjct: 1085 EQIQKLVRQVEEYKKKEEMFQKQG--KTVKELQE-QLKQAEKVNIELQKEKKNSQAEKNG 1141

Query: 1517 AKTNEMQ--TALENQEIEIVTLNDEITNLQNMVRASSSKIQK 1556
             K N  Q    L+ Q  ++  LN+E+   +N+++    K+Q+
Sbjct: 1142 QKENLEQEIKELKEQITKLQKLNNELVIYENIIQVDVRKMQE 1183



 Score =  131 bits (317), Expect = 1e-28
 Identities = 205/1045 (19%), Positives = 451/1045 (43%), Gaps = 111/1045 (10%)

Query: 237  QRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLA 296
            ++L K +  KD  +        L++  + +I     K+ Q L+                 
Sbjct: 192  EQLSKFLSQKDEELQQNNNKQYLVQIEQLQIE----KITQSLQLEEYKNKINKLQQEQEE 247

Query: 297  KQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTES 356
            K +I    ++   +    +  I     +  K + ++ ++  + + + ++E  +       
Sbjct: 248  KNNIIDQLKKNYSLNSSRNEIIQKQNMIQNKHQYIK-IDQNVLELSDDIETTVKRRTNFD 306

Query: 357  KAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQD--TDKK-----INKNEIAK 409
                  ++ G   + +KS R+  S   S       E L QD  T++K      NK ++A 
Sbjct: 307  YQAGKYNQSGKGFLEQKSPRSQFSDQDS--YLFLCEKLQQDLQTEEKQYNDLANKKQMAD 364

Query: 410  LEM-----VIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHME-GP 463
            +E      +I+ L   + +K+ +I  +D            K++   +  ++ Q  M+   
Sbjct: 365  IENDRLINLIKELEYSIQEKQLLIEHQDNEIKSNQRNIRKKESEHKKTIIQQQDDMQIYE 424

Query: 464  SLIHVGTNT--EDVN----EIAKVQEQLKQE------LNDEIKD-----VNVKDLIEKLK 506
              ++   N   E++     +I+++Q QLKQ+      L D+ KD       ++ LIE+ K
Sbjct: 425  DKLNALENLRKEELRIYEQQISQIQSQLKQKDIELKKLQDQTKDKHKLQAKIQSLIEENK 484

Query: 507  SAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHH 566
              ++ I Q+ D+ +   K  + +    +LK K++ K+  N +++ D   +I++L  EL  
Sbjct: 485  EIQQNI-QIKDQKEEDLKTKVALLQQ-QLKTKELDKS-QNSNRIYDLESQIIQLKLELEQ 541

Query: 567  --LSQKVAELEEEKGNLQLHLVDYDSGRMIE-----SDVYKKMI---EMENLAETRL--K 614
              ++ ++     +K   Q+ L ++   ++ +     S+  K++I   E+EN    +   +
Sbjct: 542  NIINAQLQTEINQKNEQQMKLKEFQINKLQDQLKEASNKQKEIITERELENQRNYQQIDE 601

Query: 615  AISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEI-KSVHLEEQIDALSA 673
               LL  Q++++ +  +++ Q+  E    +   + +  +Q+   + +  +LE+++  L  
Sbjct: 602  QNDLLRKQEYEIKRLQNLISQRPLEKNLNIQSENLVLKEQIEELLNQEANLEQKVIILET 661

Query: 674  SKK----ELALVIENLKLDKEQLYGTIKDLENDKEDIM----NKLQNYIQENMDLTDKLE 725
              K    E+ +  +   L   +L   +K  E D  D +     ++Q  I+EN  L  + E
Sbjct: 662  QLKGKDQEIIVTSQKQILSNAELQTNMKKQEADFNDKLIEKEQQIQKLIKENQSLNQENE 721

Query: 726  KM--SAEKISELLAKINHEEQSKIQT-QFGIDAKIQERDLYIENIE-SELSKY-----KS 776
            ++    +      A++  +EQ ++++ +  I  KI +  L  +    SEL+ Y     K+
Sbjct: 722  QLLHKIKNHDSRNAQLEMKEQQELESHRLEIQKKIDQIPLSDDGTTLSELNSYRMDELKT 781

Query: 777  RICRLEES-----IAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLM 831
               +LE       I  + D++  + +K DQL + +Q  ++  S+  + E+EL ++  ++ 
Sbjct: 782  FASQLESQNKKDLIQTVLDQKIEMVQKNDQLNNQVQIIEELKSKIKMNEEELKDQRELVE 841

Query: 832  DHDRVVEKQLLEIEHENKELQK-KNQILLEEN--QNLQISLSDMQQHYNALVEKANRTDL 888
                  +KQL E+    + +   +NQ+ ++E   +  Q    ++QQ    ++++  + + 
Sbjct: 842  SK----QKQLAELNSFKQSISSLENQLKVKEQSLKKAQEENKELQQQKQIVIQQKKQNET 897

Query: 889  AESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNE 948
             + ES K Q  +++ E  +K      + L    + ++ +L  + N Q+   +   KVL +
Sbjct: 898  QQQESKKLQDVIQNQEQQMKTKDENLKKL----QDQLRELGKK-NEQLSKDLNQNKVLKD 952

Query: 949  KYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYI 1008
            + EK    + Q E + +  +N I N     +++ K+  +L     +K+     +  E+  
Sbjct: 953  EVEKYKNALNQKEEEQKNLQNQISNQKKQDDQIKKLQQQL-----EKETKTKKEEIEKLQ 1007

Query: 1009 NEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVS 1068
            NEIN+LN  L+Q  +  +  NQK           + D   KL Q       ++++ ++  
Sbjct: 1008 NEINELNQELQQAQQ--LNYNQK----------KLEDQVKKLQQ------QLDQQTEKSK 1049

Query: 1069 KQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIIS-STIEPMSDDANN 1127
            KQL DS++  + LQ  ++E  +Q+ E +E  LT E  I K    +      E M      
Sbjct: 1050 KQLQDSEKKQQNLQNQLKETAEQLSEWEENDLTKEEQIQKLVRQVEEYKKKEEMFQKQGK 1109

Query: 1128 VDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTG 1187
                          + ++ ++E    ++    Q   L  E++E   +I +L+ LN EL  
Sbjct: 1110 TVKELQEQLKQAEKVNIELQKEKKNSQAEKNGQKENLEQEIKELKEQITKLQKLNNELVI 1169

Query: 1188 HDVVNQEQINQLKSKLEQLNTENDN 1212
            ++ + Q  + +++    ++    +N
Sbjct: 1170 YENIIQVDVRKMQELQRKIECLENN 1194



 Score =  112 bits (269), Expect = 9e-23
 Identities = 172/848 (20%), Positives = 389/848 (45%), Gaps = 79/848 (9%)

Query: 295  LAKQSIE-PSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIR-QTNKELENKLATM 352
            L ++ IE    +++T+ + K   +I ++ E  K+I+     N QI+ Q  ++L+ K+A +
Sbjct: 452  LKQKDIELKKLQDQTKDKHKLQAKIQSLIEENKEIQQ----NIQIKDQKEEDLKTKVALL 507

Query: 353  GTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEM 412
              + K       + S  I     +    K++   + ++++   +   K   + ++ + ++
Sbjct: 508  QQQLKTKELDKSQNSNRIYDLESQIIQLKLELEQNIINAQLQTEINQKNEQQMKLKEFQI 567

Query: 413  -VIQSLNKDLVDKEY-VISEKDTXXXXXXXXXXGKDTLIA--QLQLEHQQHMEGPSLIHV 468
              +Q   K+  +K+  +I+E++            ++ L+   + +++  Q++     +  
Sbjct: 568  NKLQDQLKEASNKQKEIITERELENQRNYQQIDEQNDLLRKQEYEIKRLQNLISQRPLEK 627

Query: 469  GTNTEDVNEIAK--VQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAAN--K 524
              N +  N + K  ++E L QE N E K + ++  + K K  E  +T     +  A    
Sbjct: 628  NLNIQSENLVLKEQIEELLNQEANLEQKVIILETQL-KGKDQEIIVTSQKQILSNAELQT 686

Query: 525  NMIKVKSNHKLKLKQMQKTIDNFSKVSDS-NKEIVRLTEELHHLSQKVAELE-EEKGNLQ 582
            NM K +++   KL + ++ I    K + S N+E  +L  ++ +   + A+LE +E+  L+
Sbjct: 687  NMKKQEADFNDKLIEKEQQIQKLIKENQSLNQENEQLLHKIKNHDSRNAQLEMKEQQELE 746

Query: 583  LHLVDYDS--GRMIESDVYKKMIEMENLAETRLKAI-SLLESQ-KFDLVQELHILQQKYD 638
             H ++      ++  SD    + E+ +     LK   S LESQ K DL+Q   +L QK +
Sbjct: 747  SHRLEIQKKIDQIPLSDDGTTLSELNSYRMDELKTFASQLESQNKKDLIQT--VLDQKIE 804

Query: 639  EVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKD 698
             V+         ++DQ+ ++++ +  EE    +  +++EL    E ++  ++QL     +
Sbjct: 805  MVQ---------KNDQLNNQVQII--EELKSKIKMNEEELKDQRELVESKQKQL----AE 849

Query: 699  LENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQ 758
            L + K+ I + L+N +        K+++ S +K  E   ++  ++Q  IQ +   + + Q
Sbjct: 850  LNSFKQSI-SSLENQL--------KVKEQSLKKAQEENKELQQQKQIVIQQKKQNETQQQ 900

Query: 759  ERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTI 818
            E     + I+++  + K++    +E++  ++D+   L +K +QL   L + +    E   
Sbjct: 901  ESKKLQDVIQNQEQQMKTK----DENLKKLQDQLRELGKKNEQLSKDLNQNKVLKDEV-- 954

Query: 819  QEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNA 878
              ++  N L    +  + ++ Q+   + ++ +++K  Q L +E +  +  +  +Q   N 
Sbjct: 955  --EKYKNALNQKEEEQKNLQNQISNQKKQDDQIKKLQQQLEKETKTKKEEIEKLQNEINE 1012

Query: 879  LVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIES 938
            L ++  +         K + Q++ L+  L + T + +  +   +K+ ++L+ +     E 
Sbjct: 1013 LNQELQQAQQLNYNQKKLEDQVKKLQQQLDQQTEKSKKQLQDSEKKQQNLQNQLKETAEQ 1072

Query: 939  AIR------DKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKH 992
                      K+   +K  + +E   + E   Q+    ++ L   +++  K+N+EL  K 
Sbjct: 1073 LSEWEENDLTKEEQIQKLVRQVEEYKKKEEMFQKQGKTVKELQEQLKQAEKVNIEL-QKE 1131

Query: 993  VQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQ 1052
             +  Q +     E    EI +L        E+I  L QK+NN  V Y +++     K+ +
Sbjct: 1132 KKNSQAEKNGQKENLEQEIKELK-------EQITKL-QKLNNELVIYENIIQVDVRKMQE 1183

Query: 1053 FTTKLENME-EEMQRVSKQLLDSKQH--NEELQI----LVREQDDQIKELKETKLTFEMN 1105
               K+E +E  + Q+ SKQ +++K        QI    ++++  DQI ++   +L  + +
Sbjct: 1184 LQRKIECLENNQSQQGSKQNIETKSQGVTPRKQIRGSSVMKQNQDQISQMTLEQL--QQH 1241

Query: 1106 IPKTEGMI 1113
            + K E +I
Sbjct: 1242 VKKLEQII 1249



 Score =  100 bits (240), Expect = 3e-19
 Identities = 188/1041 (18%), Positives = 430/1041 (41%), Gaps = 65/1041 (6%)

Query: 597  DVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVC 656
            D+ +++  + N  E  +   +LL  +K   +QE   L++  D + +   ++S++   Q+C
Sbjct: 20   DMEQRLNAVINANEKLISLQTLLLKEK---IQENDQLKENIDILYNNNQELSEINI-QLC 75

Query: 657  SEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQE 716
             +IK    ++       +  E+   +  LK   E +    ++L N ++    +LQ  I +
Sbjct: 76   EQIKRCKNQKCASLHQKNHNEMERELTQLK---ELIVSKDRELANYQQHFEEELQLEITQ 132

Query: 717  NMDLTDK---LEKMSAEKISEL--LAKINHEEQSKIQTQFGIDAKIQERDLYIENIESEL 771
              D  DK   LE+ + + I EL  + K   E Q      +  + + Q+ +  IE+++ ++
Sbjct: 133  K-DYIDKIKGLEEQNQQLIHELDLVTKKLIESQRGSLNNYDNNYQTQQYEQIIEDLQQKI 191

Query: 772  SKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTI----QEDELVNRL 827
             +    + + +E +    +++Y ++ +  Q+    Q  Q    +  I    QE E  N +
Sbjct: 192  EQLSKFLSQKDEELQQNNNKQYLVQIEQLQIEKITQSLQLEEYKNKINKLQQEQEEKNNI 251

Query: 828  AVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTD 887
               +  +  +     EI  +   +Q K+Q + + +QN+ + LSD        V++    D
Sbjct: 252  IDQLKKNYSLNSSRNEIIQKQNMIQNKHQYI-KIDQNV-LELSD---DIETTVKRRTNFD 306

Query: 888  LAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLN 947
                +  +      + +S   + + +   L + +K + +DL+ E   Q       K++ +
Sbjct: 307  YQAGKYNQSGKGFLEQKSPRSQFSDQDSYLFLCEKLQ-QDLQTE-EKQYNDLANKKQMAD 364

Query: 948  EKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQY 1007
             + ++ I  + +LE  +QE +  IE+ +  ++  N+ N+   +   +K   Q  D  + Y
Sbjct: 365  IENDRLINLIKELEYSIQEKQLLIEHQDNEIKS-NQRNIRKKESEHKKTIIQQQDDMQIY 423

Query: 1008 INEINKLNALLKQK----DEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEE 1063
             +++N L  L K++    +++I  +  ++    +  +  + D      +   K++++ EE
Sbjct: 424  EDKLNALENLRKEELRIYEQQISQIQSQLKQKDIE-LKKLQDQTKDKHKLQAKIQSLIEE 482

Query: 1064 MQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSD 1123
             + + + +    Q  E+L+  V     Q+K  +  K      I   E  II   +E +  
Sbjct: 483  NKEIQQNIQIKDQKEEDLKTKVALLQQQLKTKELDKSQNSNRIYDLESQIIQLKLE-LEQ 541

Query: 1124 DANNVDXXXXXXXXXXXXLKVQE----------------EEEFIQERSVLQEQSAKLNTE 1167
            +  N              +K++E                ++E I ER +  +++ +   E
Sbjct: 542  NIINAQLQTEINQKNEQQMKLKEFQINKLQDQLKEASNKQKEIITERELENQRNYQQIDE 601

Query: 1168 LQECYTK----IIQLETLNTELTGHDVVNQEQINQ-LKSKLEQLNTENDNLLSTVAELRS 1222
              +   K    I +L+ L ++      +N +  N  LK ++E+L  +  NL   V  L +
Sbjct: 602  QNDLLRKQEYEIKRLQNLISQRPLEKNLNIQSENLVLKEQIEELLNQEANLEQKVIILET 661

Query: 1223 SISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEE 1282
             +    DQ     ++      A+ + + +K E +   +L   E + ++L+   QS  QE 
Sbjct: 662  QLKGK-DQEIIVTSQKQILSNAELQTNMKKQEADFNDKLIEKEQQIQKLIKENQSLNQEN 720

Query: 1283 TNKIVTMEQVTSLQNKLQDKEE-----HLRNLQEKYADV-INQIEILRSEIEDEKVAFXX 1336
               +  ++   S   +L+ KE+     H   +Q+K   + ++      SE+   ++    
Sbjct: 721  EQLLHKIKNHDSRNAQLEMKEQQELESHRLEIQKKIDQIPLSDDGTTLSELNSYRMDELK 780

Query: 1337 XXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVN 1396
                               +Q  + +Q+   LN   +  +  KS              + 
Sbjct: 781  TFASQLESQNKKDLIQTVLDQKIEMVQKNDQLNNQVQIIEELKSKIKMNEEELKDQRELV 840

Query: 1397 DAEAKVL-EL-THQLELKDSEIYQKTHEYTITLTQR-NDEFENVRQQLVEYEKRIEDLTY 1453
            +++ K L EL + +  +   E   K  E ++   Q  N E +  +Q +++ +K+ E    
Sbjct: 841  ESKQKQLAELNSFKQSISSLENQLKVKEQSLKKAQEENKELQQQKQIVIQQKKQNETQQQ 900

Query: 1454 EKESELAILRLKMHENANHYETMQK-ESEIERV-KLIEELNVKITESVSLNKQVAELNKA 1511
            E +    +++ +  +     E ++K + ++  + K  E+L+  + ++  L  +V +   A
Sbjct: 901  ESKKLQDVIQNQEQQMKTKDENLKKLQDQLRELGKKNEQLSKDLNQNKVLKDEVEKYKNA 960

Query: 1512 LEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQG-RDE 1570
            L ++  +   +Q  + NQ+ +   +      L+   +    +I+K  +  ++  Q  +  
Sbjct: 961  LNQKEEEQKNLQNQISNQKKQDDQIKKLQQQLEKETKTKKEEIEKLQNEINELNQELQQA 1020

Query: 1571 QLDNTMNKELLDAVPRAELDL 1591
            Q  N   K+L D V + +  L
Sbjct: 1021 QQLNYNQKKLEDQVKKLQQQL 1041



 Score = 58.8 bits (136), Expect = 1e-06
 Identities = 132/703 (18%), Positives = 294/703 (41%), Gaps = 71/703 (10%)

Query: 933  NTQIESAIRDKKVLNEKYEKNIEYVTQL-EAQLQE---YKNNIENLNMNVEELNKMNLEL 988
            NT  +   R   V+N   EK I   T L + ++QE    K NI+ L  N +EL+++N++L
Sbjct: 16   NTIDDMEQRLNAVINAN-EKLISLQTLLLKEKIQENDQLKENIDILYNNNQELSEINIQL 74

Query: 989  ID--KHVQKQQTQS--PDYTEQYINEINKLNALLKQKDEEIIALNQ------KINNAQVS 1038
             +  K  + Q+  S       +   E+ +L  L+  KD E+    Q      ++   Q  
Sbjct: 75   CEQIKRCKNQKCASLHQKNHNEMERELTQLKELIVSKDRELANYQQHFEEELQLEITQKD 134

Query: 1039 YMSMVSDYESKLAQFTTKLENMEE---EMQRVS-------------KQLL-DSKQHNEEL 1081
            Y+  +   E +  Q   +L+ + +   E QR S             +Q++ D +Q  E+L
Sbjct: 135  YIDKIKGLEEQNQQLIHELDLVTKKLIESQRGSLNNYDNNYQTQQYEQIIEDLQQKIEQL 194

Query: 1082 QILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXX 1141
               + ++D+++++    +   ++   + E +  S  +E   +  N +             
Sbjct: 195  SKFLSQKDEELQQNNNKQYLVQIEQLQIEKITQSLQLEEYKNKINKLQQEQEEKNNIIDQ 254

Query: 1142 LKV-----QEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQI 1196
            LK          E IQ+++++Q +   +  + Q        +ET     T  D    +  
Sbjct: 255  LKKNYSLNSSRNEIIQKQNMIQNKHQYIKID-QNVLELSDDIETTVKRRTNFDYQAGKYN 313

Query: 1197 NQLKSKLEQLN-----TENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREAD-- 1249
               K  LEQ +     ++ D+ L    +L+  + +   Q   ++A   K+ +A  E D  
Sbjct: 314  QSGKGFLEQKSPRSQFSDQDSYLFLCEKLQQDLQTEEKQYN-DLAN--KKQMADIENDRL 370

Query: 1250 ---FQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHL 1306
                ++ E+ ++ +    E +  ++  + ++  ++E+    T+ Q        +DK   L
Sbjct: 371  INLIKELEYSIQEKQLLIEHQDNEIKSNQRNIRKKESEHKKTIIQQQDDMQIYEDKLNAL 430

Query: 1307 RNLQEK----YADVINQI--EILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYK 1360
             NL+++    Y   I+QI  ++ + +IE +K+                  +   E Q   
Sbjct: 431  ENLRKEELRIYEQQISQIQSQLKQKDIELKKLQDQTKDKHKLQAKIQSLIEENKEIQQNI 490

Query: 1361 QMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKT 1420
            Q+++Q   ++  + A L++              R+ D E+++++L  +LEL+ + I    
Sbjct: 491  QIKDQKEEDLKTKVALLQQQLKTKELDKSQNSNRIYDLESQIIQL--KLELEQNII---N 545

Query: 1421 HEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKES 1480
             +    + Q+N++   +++   +  K  + L      +  I+  +  EN  +Y+ + +++
Sbjct: 546  AQLQTEINQKNEQQMKLKE--FQINKLQDQLKEASNKQKEIITERELENQRNYQQIDEQN 603

Query: 1481 EIERVK--LIEELNVKITE-SVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLN 1537
            ++ R +   I+ L   I++  +  N  +   N  L+E++    E+     N E +++ L 
Sbjct: 604  DLLRKQEYEIKRLQNLISQRPLEKNLNIQSENLVLKEQI---EELLNQEANLEQKVIILE 660

Query: 1538 DEITNL-QNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKE 1579
             ++    Q ++  S  +I  +    ++ K+   +  D  + KE
Sbjct: 661  TQLKGKDQEIIVTSQKQILSNAELQTNMKKQEADFNDKLIEKE 703



 Score = 56.0 bits (129), Expect = 8e-06
 Identities = 88/407 (21%), Positives = 176/407 (43%), Gaps = 45/407 (11%)

Query: 212  EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271
            E+ K ++ KM E  +  + E  + KQ+ L ++ S    ISSLE   K+ E +  +   E+
Sbjct: 820  EELKSKI-KMNEEELKDQRELVESKQKQLAELNSFKQSISSLENQLKVKEQSLKKAQEEN 878

Query: 272  SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTK-KIEL 330
             +L Q+ +                 K+  E   +E  ++++     I N  +  K K E 
Sbjct: 879  KELQQQKQ------------IVIQQKKQNETQQQESKKLQD----VIQNQEQQMKTKDEN 922

Query: 331  LEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSG-----RNTASKMKSP 385
            L+ L  Q+R+  K+ E +L+    ++K +    +K    +++K       +N  S  K  
Sbjct: 923  LKKLQDQLRELGKKNE-QLSKDLNQNKVLKDEVEKYKNALNQKEEEQKNLQNQISNQKKQ 981

Query: 386  WSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGK 445
              Q+       + + K  K EI KL+  I  LN++L   + +   +              
Sbjct: 982  DDQIKKLQQQLEKETKTKKEEIEKLQNEINELNQELQQAQQLNYNQKKLEDQVKK----- 1036

Query: 446  DTLIAQLQLEHQQHMEGPSLIHVGTNTEDV-NEIAKVQEQLKQ-ELNDEIKDVNVKDLIE 503
                 Q QL+ Q       L       +++ N++ +  EQL + E ND  K+  ++ L+ 
Sbjct: 1037 ----LQQQLDQQTEKSKKQLQDSEKKQQNLQNQLKETAEQLSEWEENDLTKEEQIQKLVR 1092

Query: 504  KLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEE 563
            +++  +++      +     +   ++K   K+ + ++QK   N     +  KE   L +E
Sbjct: 1093 QVEEYKKKEEMFQKQGKTVKELQEQLKQAEKVNI-ELQKEKKNSQAEKNGQKE--NLEQE 1149

Query: 564  LHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAE 610
            +  L +++ +L++    L   LV Y++  +I+ DV +KM E++   E
Sbjct: 1150 IKELKEQITKLQK----LNNELVIYEN--IIQVDV-RKMQELQRKIE 1189


>UniRef50_UPI00015A55AB Cluster: UPI00015A55AB related cluster; n=1;
            Danio rerio|Rep: UPI00015A55AB UniRef100 entry - Danio
            rerio
          Length = 2213

 Score =  172 bits (418), Expect = 8e-41
 Identities = 285/1420 (20%), Positives = 616/1420 (43%), Gaps = 104/1420 (7%)

Query: 212  EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271
            E   +++ K +E+F  +  + K EK+ L K   + +  ++ L++    LE  R  IS + 
Sbjct: 165  EKMTEELKKEKESFTHLAEDTKTEKKILDKMKVANESLMADLQKEKSNLEEMRENISKQT 224

Query: 272  SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEI-ANMTELTKKIEL 330
                +E E+              + KQ  E    EK+  E++  +E+     E+ K  E 
Sbjct: 225  EDSEKEKEKIRLREDELEQLQAEIHKQQGEIKM-EKSNNEKQMKIELEREAVEIRKIKEE 283

Query: 331  LEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLS 390
            +++    + +  + L+ +      E + +     +       +  R    KM    ++  
Sbjct: 284  IQNERQNLEKMTEALKEEREAFENEKEVLKQMKTELEREAEIQKEREDLEKMNENITREM 343

Query: 391  SETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIA 450
             E  +Q+      ++E+ +L+  IQ+L ++L +KE  I  KD                + 
Sbjct: 344  HEIKHQEEQMNQKQDELDQLKTEIQNLQQEL-EKEKEIIMKDRSQLD-----------LR 391

Query: 451  QLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVN-VKDLIEKLKSAE 509
            Q +L+ QQ      +  +    + +++  +  E+ KQE+  E ++ N ++ +  +L+   
Sbjct: 392  QSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKEREEKNKLEQMKIELEREA 451

Query: 510  EQITQLNDEIDAANKNMIKVK---SNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEE--L 564
            ++I+++ +E     + + K+     N K  +KQM KT D   +  +  KE +   +E  L
Sbjct: 452  DEISKIKEETQNKRQRLEKMTEAFENEKEAMKQM-KT-DLQIQADEIVKEDLEKQKENTL 509

Query: 565  HHLSQKVAELEEEKGNL--QLHLVDYDSGRM--IESDVYKKMIEMENLAE--TRLKAISL 618
              + ++  ++E+   N+  ++H + +   +M   + ++ +   E++NL +   + K I +
Sbjct: 510  AEIQKEREDVEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEIIM 569

Query: 619  LESQKFDLVQ-ELHILQQKYDEVEDKLA-DISQLQSDQVCSEIKSVHLEEQIDALSASKK 676
             +  +FDL Q EL   Q   +++ + +  +  QL  D+   E +   +E++      S+K
Sbjct: 570  KDRSQFDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKEKHDFDQSRK 629

Query: 677  ELALVIENLKLDK---EQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAE--K 731
             L   ++ +KL K   E+    ++ ++ + E   ++++   +E  +    LEKM+ E  K
Sbjct: 630  SLDKDLKMMKLQKQVFEEEKNKLEQMKIELEREADEIRKIKEETQNERQSLEKMTEELKK 689

Query: 732  ISELLAKINHEEQSKIQTQFGIDAKIQE--RDLYIENIESELSKYKSRICRLEESIAVME 789
              E    +   ++   + +    A+IQ+   DL ++  +S L + K  I +  E I   +
Sbjct: 690  EKESFTHLAEVKEDLEKQKENTLAQIQKEREDLDLQKEKSNLEEMKENISKQTEDIEKEK 749

Query: 790  DRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENK 849
            D+   +  + D+L     E  K  SE  I++  +    A ++     ++ +++ ++ + +
Sbjct: 750  DK---IRLREDELEQLQAEIHKQQSETEIEKSNIERERAAIIKDVEDLQSKIISLDRDAE 806

Query: 850  ELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKR 909
             L+   +    E + L+   +++++  + + +    T        +      +  +N ++
Sbjct: 807  SLKLDREAFENEKEELKQMKTELEREADEIEKIKLETQHERQRVEEMTADFMETMNNERK 866

Query: 910  ITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNI----EYVTQLEAQLQ 965
               +++ +I ++K+E+E    + +   +S   D K++  + E  +    E + Q + ++ 
Sbjct: 867  QLDKNKVMIEEQKQEMEKKRDDMDQSRKSLDEDLKMMKAQKESELAKLQEDILQQQQEMD 926

Query: 966  EYKNNIE-NLNMNVEELNKMNLELID-KHVQKQQTQSPDYTEQYINEINKLNALLKQKDE 1023
            E K ++E   +  +E+   +  + +D ++V++ +T+  D  E       +L       +E
Sbjct: 927  EQKQDLERERDELLEQWRLVETQKMDNENVKQLKTELLDEKESTEKIRKQLEQDKAYMEE 986

Query: 1024 EIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEE-LQ 1082
              + L++++    +     + D E  + Q   K+E+ E E+Q+  K+L  S++  E+ +Q
Sbjct: 987  NKLNLHKELEELNLQKQG-IQDKEEMVKQ---KIES-EREIQQEKKKLQRSEEELEDKMQ 1041

Query: 1083 ILVREQDDQIKELKETKLTFEMNIPKTEGM-IISSTIEPMSDDANNVDXXXXXXXXXXXX 1141
             + RE  +Q K+L +     +  I K + M  I S I   +++ N               
Sbjct: 1042 KIKREMIEQKKDLDQ---KMKQVIRKRDEMEKIRSDIANATEEINRERQELEILRNNVQS 1098

Query: 1142 LKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKS 1201
             +   E    +  ++  E+SA  + E +E    +I  E +  E T  D+  Q+   +L+S
Sbjct: 1099 ARHDFELLLERTANLEDEESAATDIERRELVEAVIDKEEMK-EFT--DI--QKYKEELQS 1153

Query: 1202 KLEQLNTEN---DNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELR 1258
              E+L T+    D L S V +LR +I            E+  QH  ++ A+ +    EL+
Sbjct: 1154 VTEELLTKKRDLDQLNSDVQDLRQTIE-----------EINIQH-GKKRAELEGIGFELK 1201

Query: 1259 VQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTS--LQNKLQDKEEHLRNLQEKYADV 1316
                  E + ++L ++     +E  NK  ++E++    L+++LQ + E L    +K    
Sbjct: 1202 KGEQLLEKQKDELKEN-GWIVEEIKNKKDSLEKINMEILRSELQRQREDLETSIQKLTHE 1260

Query: 1317 INQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQ 1376
              ++E+LRSEI  EK                   DL  +     QMQ Q I   N E   
Sbjct: 1261 KREMEVLRSEIVLEKKDLDQKMKQDANSESDRLKDLSMK----LQMQRQDIEKTNTEMET 1316

Query: 1377 LKKSSXXXXXXXXXXXXRV-NDAEAKVLELTHQLELKDSEIYQKTHEYTI----TLTQRN 1431
             K+S             R+ ND +A   ++TH LELK  E+ ++     +     L +RN
Sbjct: 1317 KKRSLDRMSRELQDDKIRLKNDRDAYEKDMTH-LELKREELQREQEALEVMKVDILKKRN 1375

Query: 1432 D---EFENV---RQQLV-----EYEKRIEDLTYEKESELAILRLKMHENANHYETMQKES 1480
            +   E ENV   RQ+L+     ++ K+ +  T E   +LA +   +    N Y  + +E 
Sbjct: 1376 EFAKEMENVHSERQKLLLLQEQKHLKQAKAETEECRKQLAEMSETVTTEQNEYRKLIEEL 1435

Query: 1481 EIERVKLIEELNVKITESVSLNKQVAELNKALEEEV----AKTNEMQTALENQEIEIVTL 1536
            + E+ +L    N    E   L    + L +   E++     +    +  +E +   +   
Sbjct: 1436 QREKEQLEISKNQIEQEKKDLQNMKSNLERKEREDLENCWVEIEGEKKRMEEETRRLEMH 1495

Query: 1537 NDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTM 1576
             +EI  + + ++    +++  +   +  KQ  +E+ +N M
Sbjct: 1496 REEIKKVDSELQKKKKELEDQMMDLTREKQETEEERNNLM 1535



 Score =  170 bits (413), Expect = 3e-40
 Identities = 321/1659 (19%), Positives = 682/1659 (41%), Gaps = 144/1659 (8%)

Query: 5    KNIDHPSEMELSEETTARLPSSEVSSV-AGXXXXXXXXXXXXXXXERQIKFERAQKCLEN 63
            +NI   +E    E+   RL   E+  + A                E+Q+K E     LE 
Sbjct: 218  ENISKQTEDSEKEKEKIRLREDELEQLQAEIHKQQGEIKMEKSNNEKQMKIE-----LER 272

Query: 64   AALVSKRIKEHRKATAELLGRPFVPGISESLANTLKQKEILMEKIKQYKELSKRSSTTIV 123
             A+  ++IKE  +   + L         E +   LK++    E  +  KE+ K+  T + 
Sbjct: 273  EAVEIRKIKEEIQNERQNL---------EKMTEALKEER---EAFENEKEVLKQMKTELE 320

Query: 124  RXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKD 183
            R               +  ++T   + IK ++  ++  Q ++  ++T I +LQ+++ ++ 
Sbjct: 321  REAEIQKEREDLEKMNE--NITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEK 378

Query: 184  QIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKD-EKQRLLKD 242
            +II                         E  K +  ++ ++   ME + ++ EK+R  K+
Sbjct: 379  EIIMKDRSQLDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQKQEMEKEREEKN 438

Query: 243  -IESKDVRIS-SLEEANKLLEAA---RFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAK 297
             +E   + +    +E +K+ E     R  +         E E               + K
Sbjct: 439  KLEQMKIELEREADEISKIKEETQNKRQRLEKMTEAFENEKEAMKQMKTDLQIQADEIVK 498

Query: 298  QSIEPSCEEKTEIEEKGSLEIANMTE-LTKKIELLEHLNCQIRQTNKELENKLATMGTES 356
            + +E   E      +K   ++  M E +T+++  ++H   Q+ Q   EL+     + TE 
Sbjct: 499  EDLEKQKENTLAEIQKEREDVEKMNENITREMHEIKHQEEQMNQKQDELDQ----LKTEI 554

Query: 357  KAVSSPSKKGSPLISRKSGR-----NTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLE 411
            + +    +K   +I +   +     +   K ++  + +     N+      +K E+ + +
Sbjct: 555  QNLQQELEKEKEIIMKDRSQFDLRQSELDKQQTNMNDIMETMKNERKQLDKDKEEMEEQK 614

Query: 412  MVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKD-TLIAQLQLEHQQHMEGPSLIHVGT 470
              ++    D  D+     +KD            ++   + Q+++E ++  +    I   T
Sbjct: 615  QEMEKEKHDF-DQSRKSLDKDLKMMKLQKQVFEEEKNKLEQMKIELEREADEIRKIKEET 673

Query: 471  NTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVK 530
              E    + K+ E+LK+E         VK+ +EK K  E  + Q+  E +  + ++ K K
Sbjct: 674  QNER-QSLEKMTEELKKEKESFTHLAEVKEDLEKQK--ENTLAQIQKERE--DLDLQKEK 728

Query: 531  SNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHL--VDY 588
            SN    L++M++ I   ++  +  K+ +RL E+   L Q  AE+ +++   ++    ++ 
Sbjct: 729  SN----LEEMKENISKQTEDIEKEKDKIRLRED--ELEQLQAEIHKQQSETEIEKSNIER 782

Query: 589  DSGRMIES--DVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDE------- 639
            +   +I+   D+  K+I ++  AE+        E++K +L Q    L+++ DE       
Sbjct: 783  ERAAIIKDVEDLQSKIISLDRDAESLKLDREAFENEKEELKQMKTELEREADEIEKIKLE 842

Query: 640  -------VEDKLADI--------SQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIEN 684
                   VE+  AD          QL  ++V  E +   +E++ D +  S+K L   ++ 
Sbjct: 843  TQHERQRVEEMTADFMETMNNERKQLDKNKVMIEEQKQEMEKKRDDMDQSRKSLDEDLKM 902

Query: 685  LKLDKE-QLYGTIKDLENDKEDIMNKLQNYIQENMDLTDK-----LEKMSAEKISELLAK 738
            +K  KE +L    +D+   ++++  + Q+  +E  +L ++      +KM  E + +L  +
Sbjct: 903  MKAQKESELAKLQEDILQQQQEMDEQKQDLERERDELLEQWRLVETQKMDNENVKQLKTE 962

Query: 739  INHEEQS--KIQTQFGID-AKIQERDLYIENIESELSKYKSRICRLEESIA--VMEDRRY 793
            +  E++S  KI+ Q   D A ++E  L +     EL+  K  I   EE +   +  +R  
Sbjct: 963  LLDEKESTEKIRKQLEQDKAYMEENKLNLHKELEELNLQKQGIQDKEEMVKQKIESEREI 1022

Query: 794  SLERKADQLGSY-LQEK-QKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKEL 851
              E+K  Q     L++K QK   E   Q+ +L  ++  ++     +EK   +I +  +E+
Sbjct: 1023 QQEKKKLQRSEEELEDKMQKIKREMIEQKKDLDQKMKQVIRKRDEMEKIRSDIANATEEI 1082

Query: 852  QKKNQILLEENQNLQISLSD----MQQHYNALVEKANRTDLAESESTKYQTQLRDLE--S 905
             ++ Q L     N+Q +  D    +++  N   E++  TD+   E  +      +++  +
Sbjct: 1083 NRERQELEILRNNVQSARHDFELLLERTANLEDEESAATDIERRELVEAVIDKEEMKEFT 1142

Query: 906  NLKRITHEHQTL---IVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYV----- 957
            ++++   E Q++   ++ KK++++ L  +    +   I +  + + K    +E +     
Sbjct: 1143 DIQKYKEELQSVTEELLTKKRDLDQLNSDVQ-DLRQTIEEINIQHGKKRAELEGIGFELK 1201

Query: 958  ---TQLEAQLQEYKNN---IENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEI 1011
                 LE Q  E K N   +E +    + L K+N+E++   +Q+Q+       ++  +E 
Sbjct: 1202 KGEQLLEKQKDELKENGWIVEEIKNKKDSLEKINMEILRSELQRQREDLETSIQKLTHEK 1261

Query: 1012 NKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQL 1071
             ++  L  +   E   L+QK+     S    + D   KL      +E    EM+   K+ 
Sbjct: 1262 REMEVLRSEIVLEKKDLDQKMKQDANSESDRLKDLSMKLQMQRQDIEKTNTEME-TKKRS 1320

Query: 1072 LDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXX 1131
            LD  + + EL      QDD+I+ LK  +  +E ++   E        E  + +   VD  
Sbjct: 1321 LD--RMSREL------QDDKIR-LKNDRDAYEKDMTHLELKREELQREQEALEVMKVDIL 1371

Query: 1132 XXXXXXXXXXLKVQEEEEFIQERSVLQEQS--AKLNTELQECYTKIIQL-ETLNTELTGH 1188
                        V  E    Q+  +LQEQ    +   E +EC  ++ ++ ET+ TE   +
Sbjct: 1372 KKRNEFAKEMENVHSER---QKLLLLQEQKHLKQAKAETEECRKQLAEMSETVTTEQNEY 1428

Query: 1189 DVVNQE---QINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQ 1245
              + +E   +  QL+    Q+  E  +L +  + L       ++    EI E  K+ + +
Sbjct: 1429 RKLIEELQREKEQLEISKNQIEQEKKDLQNMKSNLERKEREDLENCWVEI-EGEKKRMEE 1487

Query: 1246 READFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEH 1305
                 +    E++   S  + K ++L D +   T+E+         + +L+N+L+D  + 
Sbjct: 1488 ETRRLEMHREEIKKVDSELQKKKKELEDQMMDLTREKQETEEERNNLMALKNQLEDLRKE 1547

Query: 1306 LRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQ 1365
               ++EK     + IE ++ +I  ++                     R E +  KQM E 
Sbjct: 1548 NEIVKEKLTLEKSNIEEMQLKIFKQQ-RLNDQTREENKKEKESLEQQRFETEQQKQMLEI 1606

Query: 1366 SILNINEEN---AQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQK--- 1419
            S   + EE    A L +              + N    +V ++  +L  +   I Q+   
Sbjct: 1607 STTKMMEEKNEMADLSRELQKAKDELEKIAYKTNKERHEVEQMQAELHSQIQAIEQQGQI 1666

Query: 1420 THEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKE---SELAILRLKMHENANHYETM 1476
              +    L ++    +  R+Q  + EK   D+  + +    +  +L  +  +  +  E +
Sbjct: 1667 MQDKQNHLEEKELSIQKTRRQKEDLEKMSTDIKEQNQDLMKQRDLLEQEKEDIKSELERV 1726

Query: 1477 QKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTL 1536
            + E + E+ KL + + +   E   L K  +E+ K  ++   + +E+   ++   +E    
Sbjct: 1727 RSEIDHEQKKLNDYMKMIEQEKEDLEKMKSEIMKQRQQMEEERSELDNKIQQTNLE---- 1782

Query: 1537 NDEITNLQNMVRASSSKIQKHVSFASD-TKQGRDEQLDN 1574
              +I   + +V     ++++      D TKQ  +E+ ++
Sbjct: 1783 KHDIEKSKEIVEKLMVEVEEQSKQREDLTKQEMEEEKED 1821



 Score =  167 bits (406), Expect = 2e-39
 Identities = 278/1497 (18%), Positives = 653/1497 (43%), Gaps = 101/1497 (6%)

Query: 152  KEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXX 211
            K+K+N L+ +Q      E   LDLQ++ +  +++ E  +K T                  
Sbjct: 706  KQKENTLAQIQ-----KEREDLDLQKEKSNLEEMKENISKQTEDIEKEKDKIRLREDEL- 759

Query: 212  EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLE-EANKL-LEAARFEISL 269
            E  + ++ K Q      ++  + E+  ++KD+E    +I SL+ +A  L L+   FE   
Sbjct: 760  EQLQAEIHKQQSETEIEKSNIERERAAIIKDVEDLQSKIISLDRDAESLKLDREAFENEK 819

Query: 270  EHSK-LAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEE--KTEIEEKGSLEIANMTELTK 326
            E  K +  ELE+                +Q +E    +  +T   E+  L+  N   + +
Sbjct: 820  EELKQMKTELEREADEIEKIKLETQH-ERQRVEEMTADFMETMNNERKQLD-KNKVMIEE 877

Query: 327  KIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASK-MKSP 385
            + + +E     + Q+ K L+  L  M  + +  S  +K    ++ ++   +   + ++  
Sbjct: 878  QKQEMEKKRDDMDQSRKSLDEDLKMMKAQKE--SELAKLQEDILQQQQEMDEQKQDLERE 935

Query: 386  WSQLSSETLNQDTDKKINKN-EIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXG 444
              +L  +    +T K  N+N +  K E++ +  + + + K+    E+D            
Sbjct: 936  RDELLEQWRLVETQKMDNENVKQLKTELLDEKESTEKIRKQL---EQDKAYMEENKLNLH 992

Query: 445  KDTLIAQLQLEHQQHMEGPSLIHVGTNTE-DVNEIAKVQEQLKQELNDEIKDVNVKDLIE 503
            K+  + +L L+ Q   +   ++     +E ++ +  K  ++ ++EL D+++ +  +++IE
Sbjct: 993  KE--LEELNLQKQGIQDKEEMVKQKIESEREIQQEKKKLQRSEEELEDKMQKIK-REMIE 1049

Query: 504  KLKSAEEQITQL---NDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRL 560
            + K  ++++ Q+    DE++    ++         + ++++   +N        + ++  
Sbjct: 1050 QKKDLDQKMKQVIRKRDEMEKIRSDIANATEEINRERQELEILRNNVQSARHDFELLLER 1109

Query: 561  TEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAE---TRLKAIS 617
            T  L    ++ A  + E+  L   ++D +  +   +D+ K   E++++ E   T+ + + 
Sbjct: 1110 TANLE--DEESAATDIERRELVEAVIDKEEMKEF-TDIQKYKEELQSVTEELLTKKRDLD 1166

Query: 618  LLESQKFDLVQELHILQQKYDEVEDKLADIS-QLQSDQVCSEIKSVHLEEQ---IDAL-- 671
             L S   DL Q +  +  ++ +   +L  I  +L+  +   E +   L+E    ++ +  
Sbjct: 1167 QLNSDVQDLRQTIEEINIQHGKKRAELEGIGFELKKGEQLLEKQKDELKENGWIVEEIKN 1226

Query: 672  ---SASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEK-- 726
               S  K  + ++   L+  +E L  +I+ L ++K ++       + E  DL  K+++  
Sbjct: 1227 KKDSLEKINMEILRSELQRQREDLETSIQKLTHEKREMEVLRSEIVLEKKDLDQKMKQDA 1286

Query: 727  -MSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESI 785
               ++++ +L  K+  + Q   +T   ++ K +  D     ++ +  + K+     E+ +
Sbjct: 1287 NSESDRLKDLSMKLQMQRQDIEKTNTEMETKKRSLDRMSRELQDDKIRLKNDRDAYEKDM 1346

Query: 786  AVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVN--RLAVLMDHDRVVEKQLLE 843
              +E +R  L+R+ + L     +  K  +E+  + + + +  +  +L+   + +++   E
Sbjct: 1347 THLELKREELQREQEALEVMKVDILKKRNEFAKEMENVHSERQKLLLLQEQKHLKQAKAE 1406

Query: 844  IEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKAN-----RTDLAESESTKYQT 898
             E   K+L + ++ +  E    +  + ++Q+    L    N     + DL   +S   + 
Sbjct: 1407 TEECRKQLAEMSETVTTEQNEYRKLIEELQREKEQLEISKNQIEQEKKDLQNMKSNLERK 1466

Query: 899  QLRDLESNLKRITHEHQTLIVQKKK-EIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYV 957
            +  DLE+    I  E + +  + ++ E+   EI+   +++S ++ KK   ++ E  +  +
Sbjct: 1467 EREDLENCWVEIEGEKKRMEEETRRLEMHREEIK---KVDSELQKKK---KELEDQMMDL 1520

Query: 958  TQLEAQLQEYKNNIENLNMNVEELNKMNLELIDK-HVQK---QQTQSPDYTEQYINE-IN 1012
            T+ + + +E +NN+  L   +E+L K N  + +K  ++K   ++ Q   + +Q +N+   
Sbjct: 1521 TREKQETEEERNNLMALKNQLEDLRKENEIVKEKLTLEKSNIEEMQLKIFKQQRLNDQTR 1580

Query: 1013 KLNALLKQK-DEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVS--- 1068
            + N   K+  +++     Q+    ++S   M+ + ++++A  + +L+  ++E+++++   
Sbjct: 1581 EENKKEKESLEQQRFETEQQKQMLEISTTKMMEE-KNEMADLSRELQKAKDELEKIAYKT 1639

Query: 1069 -KQLLDSKQHNEEL--QILVREQDDQIKELKETKLTF-EMNIPKTEGMIISSTIEPMSDD 1124
             K+  + +Q   EL  QI   EQ  QI + K+  L   E++I KT        +E MS D
Sbjct: 1640 NKERHEVEQMQAELHSQIQAIEQQGQIMQDKQNHLEEKELSIQKTRRQ--KEDLEKMSTD 1697

Query: 1125 ANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTE 1184
                +             K   + E  + RS +  +  KLN  ++    +   LE + +E
Sbjct: 1698 IKEQNQDLMKQRDLLEQEKEDIKSELERVRSEIDHEQKKLNDYMKMIEQEKEDLEKMKSE 1757

Query: 1185 LTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLA 1244
            +       +E+ ++L +K++Q N E  ++  +  E+   +   V+++  +  +L KQ + 
Sbjct: 1758 IMKQRQQMEEERSELDNKIQQTNLEKHDIEKS-KEIVEKLMVEVEEQSKQREDLTKQEME 1816

Query: 1245 QREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEE 1304
            + + D +K + E+  Q    E +  +L + ++ +  E  +   + E V  L  K++++ +
Sbjct: 1817 EEKEDLEKMKSEIMTQRQQMEEERSELDNKIKQTDLERHDIENSKEIVQKLMVKVEEQRK 1876

Query: 1305 HLRNLQEKYADVINQIEILRSEIEDEK-VAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQ 1363
             +R LQ++      +++I R +I DE+ +                  D     Q  + + 
Sbjct: 1877 DIR-LQKE------ELDIERQKIADEQGLVVQNKAKLQNENERIKEMDEEINKQKEEDLT 1929

Query: 1364 EQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELT-HQLELKDSEIYQK--- 1419
            +Q  +   +E+ +  KS                D + K  +L  H +E    EI QK   
Sbjct: 1930 KQKKMEEEKEDLEKMKSEIMKQRQQMEEERSELDNKIKQTDLERHDIE-NSKEIVQKLMV 1988

Query: 1420 -THEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQK 1478
               E    +  + +E +  RQ++ + +  +     + ++E   ++    E     ET+ K
Sbjct: 1989 EVEEQRKDIRLQKEELDIERQKIADEQGLVVQNKAKLQNENERIKEMDEEIKKEKETL-K 2047

Query: 1479 ESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQ-------TALENQEI 1531
            E E    K  EE+   I E+    K+  E  + L+ E  K  + Q       + L+N+  
Sbjct: 2048 EMEAHLRKEKEEMRSVIEETQRRQKEDLEKKEELDIERQKIADEQDLLIQNKSELQNENE 2107

Query: 1532 EIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAE 1588
             I  +N+ I   +  ++    K ++ +    + K+ R + L+ T    +L+   +AE
Sbjct: 2108 RIKNINEVIKKERETLKEIKQK-EEDLPKEKEMKEDR-KSLEET-KANILEMKTKAE 2161



 Score =  147 bits (357), Expect = 2e-33
 Identities = 255/1411 (18%), Positives = 591/1411 (41%), Gaps = 103/1411 (7%)

Query: 213  DTKQQMTKMQENFIAMEAEWKDEKQRLLK---DIESKDVRISSLEEANKLLEAARFEISL 269
            D  Q    + E+   M+ + ++ ++ + K   D+E+K  +I   EE  K L+A   EI  
Sbjct: 7    DFDQSRKSLDEDLKMMKLQKQEMRENISKQTEDVENKKEKIRLREEKLKQLQA---EIHK 63

Query: 270  EHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANM-TELTKKI 328
            + S+  +E                 L  +  E S +   E  E    E+  M TEL ++ 
Sbjct: 64   QQSETEKEKSNIERERAAIIKDVEDLQNRDAE-SLKLDREAFENEKEELKQMKTELEREA 122

Query: 329  ELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQ 388
            + +E +  + +   + +E   A        +   ++     + + +      K K  ++ 
Sbjct: 123  DEIEKIKLETQHERQRVEEMTADFMETMNNIKEETQNERQRLEKMT--EELKKEKESFTH 180

Query: 389  LSSETLNQDTDKKI-NKNEIAKLEMV--IQSLNKDLVDKEYVISEKDTXXXXXXXXXXGK 445
            L+ +T    T+KKI +K ++A   ++  +Q    +L +    IS++             +
Sbjct: 181  LAEDT---KTEKKILDKMKVANESLMADLQKEKSNLEEMRENISKQTEDSEKEKEKIRLR 237

Query: 446  DTLIAQLQLE-HQQHME-------GPSLIHVGTNTEDVNEIAKVQEQLKQEL-NDEIKDV 496
            +  + QLQ E H+Q  E           + +    E V EI K++E+++ E  N E    
Sbjct: 238  EDELEQLQAEIHKQQGEIKMEKSNNEKQMKIELEREAV-EIRKIKEEIQNERQNLEKMTE 296

Query: 497  NVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLK---LKQMQKTIDNFSKVSDS 553
             +K+  E  ++ +E + Q+  E++   +   + +   K+     ++M +      +++  
Sbjct: 297  ALKEEREAFENEKEVLKQMKTELEREAEIQKEREDLEKMNENITREMHEIKHQEEQMNQK 356

Query: 554  NKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRL 613
              E+ +L  E+ +L Q   ELE+EK   ++ + D     + +S++ K+   M ++ ET  
Sbjct: 357  QDELDQLKTEIQNLQQ---ELEKEK---EIIMKDRSQLDLRQSELDKQQTNMNDIMETMK 410

Query: 614  KAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSA 673
                 L+  K ++ ++   ++++ +E ++KL  + +++ ++   EI  +  E Q      
Sbjct: 411  NERKQLDKDKEEMEEQKQEMEKEREE-KNKLEQM-KIELEREADEISKIKEETQNKRQRL 468

Query: 674  SKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKIS 733
             K   A   E   + + +    I+  E  KED+  + +N + E     + +EKM+ E I+
Sbjct: 469  EKMTEAFENEKEAMKQMKTDLQIQADEIVKEDLEKQKENTLAEIQKEREDVEKMN-ENIT 527

Query: 734  ELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRY 793
              + +I H+E+   Q Q  +D    E    I+N++ EL K K  I +      +   R+ 
Sbjct: 528  REMHEIKHQEEQMNQKQDELDQLKTE----IQNLQQELEKEKEIIMKDRSQFDL---RQS 580

Query: 794  SLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQK 853
             L+++   +   ++  +    +    ++E       + +  + +EK+  + +   K L K
Sbjct: 581  ELDKQQTNMNDIMETMKNERKQLDKDKEE-------MEEQKQEMEKEKHDFDQSRKSLDK 633

Query: 854  KNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHE 913
              +++  + Q  +   + ++Q    L  +A+     + E+   +  L  +   LK+   E
Sbjct: 634  DLKMMKLQKQVFEEEKNKLEQMKIELEREADEIRKIKEETQNERQSLEKMTEELKK-EKE 692

Query: 914  HQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQ-LEAQLQEYKNNIE 972
              T + + K+++E  +     QI+    D  +  EK   N+E + + +  Q ++ +   +
Sbjct: 693  SFTHLAEVKEDLEKQKENTLAQIQKEREDLDLQKEK--SNLEEMKENISKQTEDIEKEKD 750

Query: 973  NLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKI 1032
             + +  +EL ++  E     + KQQ+++         E   +   ++    +II+L++  
Sbjct: 751  KIRLREDELEQLQAE-----IHKQQSETEIEKSNIERERAAIIKDVEDLQSKIISLDRDA 805

Query: 1033 NNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQI-LVREQDDQ 1091
             + ++   +  ++ E +L Q  T+LE   +E++++  +    +Q  EE+    +   +++
Sbjct: 806  ESLKLDREAFENEKE-ELKQMKTELEREADEIEKIKLETQHERQRVEEMTADFMETMNNE 864

Query: 1092 IKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFI 1151
             K+L + K+  E    K E   +    + M     ++D               + +E+ +
Sbjct: 865  RKQLDKNKVMIEEQ--KQE---MEKKRDDMDQSRKSLDEDLKMMKAQKESELAKLQEDIL 919

Query: 1152 QERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTEND 1211
            Q++  + EQ   L  E  E   +   +ET   +      +  E +++ K   E++  + +
Sbjct: 920  QQQQEMDEQKQDLERERDELLEQWRLVETQKMDNENVKQLKTELLDE-KESTEKIRKQLE 978

Query: 1212 NLLSTVAELRSSISSAVDQRGFEIAELW-KQHLAQREADFQKTEHELRVQLSAFESKYEQ 1270
               + + E + ++   +++   +   +  K+ + +++ + ++   + + +L   E + E 
Sbjct: 979  QDKAYMEENKLNLHKELEELNLQKQGIQDKEEMVKQKIESEREIQQEKKKLQRSEEELED 1038

Query: 1271 LLDSVQSSTQEETNKI-VTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIED 1329
             +  ++    E+   +   M+QV   +++++     + N  E+      ++EILR+ ++ 
Sbjct: 1039 KMQKIKREMIEQKKDLDQKMKQVIRKRDEMEKIRSDIANATEEINRERQELEILRNNVQS 1098

Query: 1330 EKVAFXXXXXXXXXXXXXXXXDLRTENQSY-------KQMQE-QSILNINEENAQLKKSS 1381
             +  F                    E +         ++M+E   I    EE   + +  
Sbjct: 1099 ARHDFELLLERTANLEDEESAATDIERRELVEAVIDKEEMKEFTDIQKYKEELQSVTEEL 1158

Query: 1382 XXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQL 1441
                         V D    + E+  Q   K +E+     E    L +     E  + +L
Sbjct: 1159 LTKKRDLDQLNSDVQDLRQTIEEINIQHGKKRAELEGIGFE----LKKGEQLLEKQKDEL 1214

Query: 1442 VEYEKRIEDLTYEKES----ELAILRLKMHENANHYETM-------QKESEIERVKLI-- 1488
             E    +E++  +K+S     + ILR ++       ET        ++E E+ R +++  
Sbjct: 1215 KENGWIVEEIKNKKDSLEKINMEILRSELQRQREDLETSIQKLTHEKREMEVLRSEIVLE 1274

Query: 1489 -EELNVKITESV-SLNKQVAELNKALE---EEVAKTN-EMQTALENQEIEIVTLNDEITN 1542
             ++L+ K+ +   S + ++ +L+  L+   +++ KTN EM+T   + +     L D+   
Sbjct: 1275 KKDLDQKMKQDANSESDRLKDLSMKLQMQRQDIEKTNTEMETKKRSLDRMSRELQDDKIR 1334

Query: 1543 LQNMVRASSSKIQKHVSFASDTKQGRDEQLD 1573
            L+N  R +  K   H+    +  Q   E L+
Sbjct: 1335 LKN-DRDAYEKDMTHLELKREELQREQEALE 1364



 Score =  142 bits (343), Expect = 9e-32
 Identities = 252/1327 (18%), Positives = 564/1327 (42%), Gaps = 122/1327 (9%)

Query: 213  DTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEA---ARFEISL 269
            D K+   K+++     +A  ++ K  L K++E  +++   +++  ++++    +  EI  
Sbjct: 965  DEKESTEKIRKQLEQDKAYMEENKLNLHKELEELNLQKQGIQDKEEMVKQKIESEREIQQ 1024

Query: 270  EHSKLA---QELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTE-LT 325
            E  KL    +ELE                  Q ++    ++ E+E+  S +IAN TE + 
Sbjct: 1025 EKKKLQRSEEELEDKMQKIKREMIEQKKDLDQKMKQVIRKRDEMEKIRS-DIANATEEIN 1083

Query: 326  KKIELLEHLNCQIRQTNKELENKLA-TMGTESKAVSSPSKKGSPLISRKSGRNTASKMKS 384
            ++ + LE L   ++    + E  L  T   E +  ++   +   L+     +    +   
Sbjct: 1084 RERQELEILRNNVQSARHDFELLLERTANLEDEESAATDIERRELVEAVIDKEEMKEFTD 1143

Query: 385  PWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXG 444
               Q   E L   T++ + K         +  LN D+ D    I E +           G
Sbjct: 1144 --IQKYKEELQSVTEELLTKKRD------LDQLNSDVQDLRQTIEEINIQH--------G 1187

Query: 445  KDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEK 504
            K    A+L+    +  +G  L+      +++ E   + E++K +  D ++ +N++ L  +
Sbjct: 1188 KKR--AELEGIGFELKKGEQLLE--KQKDELKENGWIVEEIKNK-KDSLEKINMEILRSE 1242

Query: 505  LKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQM-QKTIDNFSKVSDSNKEI-VRLTE 562
            L+   E +     ++    + M  ++S   L+ K + QK   + +  SD  K++ ++L  
Sbjct: 1243 LQRQREDLETSIQKLTHEKREMEVLRSEIVLEKKDLDQKMKQDANSESDRLKDLSMKLQM 1302

Query: 563  ELHHLSQKVAELEEEKGNLQL---HLVDYDSGRMIESDVYKK-MIEMENLAETRLKAISL 618
            +   + +   E+E +K +L      L D       + D Y+K M  +E   E   +    
Sbjct: 1303 QRQDIEKTNTEMETKKRSLDRMSRELQDDKIRLKNDRDAYEKDMTHLELKREELQREQEA 1362

Query: 619  LESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSV------HLEEQIDALS 672
            LE  K D++++ +   ++ + V  +   +  LQ  +   + K+        L E  + ++
Sbjct: 1363 LEVMKVDILKKRNEFAKEMENVHSERQKLLLLQEQKHLKQAKAETEECRKQLAEMSETVT 1422

Query: 673  ASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQ-ENMDLTDKLEKMSAEK 731
              + E   +IE L+ +KEQL  +   +E +K+D+ N   N  + E  DL +   ++  EK
Sbjct: 1423 TEQNEYRKLIEELQREKEQLEISKNQIEQEKKDLQNMKSNLERKEREDLENCWVEIEGEK 1482

Query: 732  --ISELLAKIN-HEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVM 788
              + E   ++  H E+ K      +D+++Q++   +E+   +L++ K             
Sbjct: 1483 KRMEEETRRLEMHREEIK-----KVDSELQKKKKELEDQMMDLTREKQET---------- 1527

Query: 789  EDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHEN 848
            E+ R +L    +QL    +E +    + T+++  +      +    R+ ++   E + E 
Sbjct: 1528 EEERNNLMALKNQLEDLRKENEIVKEKLTLEKSNIEEMQLKIFKQQRLNDQTREENKKEK 1587

Query: 849  KELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLK 908
            + L+++     ++ Q L+IS + M +  N + + +     A+ E  K   +       ++
Sbjct: 1588 ESLEQQRFETEQQKQMLEISTTKMMEEKNEMADLSRELQKAKDELEKIAYKTNKERHEVE 1647

Query: 909  RITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYK 968
            ++  E  + I   +++ + ++ + N   E  +  +K   +K +   +  T ++ Q Q+  
Sbjct: 1648 QMQAELHSQIQAIEQQGQIMQDKQNHLEEKELSIQKTRRQKEDLE-KMSTDIKEQNQDLM 1706

Query: 969  NNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYT---EQYINEINKLNA-LLKQK--- 1021
               + L    E++ K  LE +   +  +Q +  DY    EQ   ++ K+ + ++KQ+   
Sbjct: 1707 KQRDLLEQEKEDI-KSELERVRSEIDHEQKKLNDYMKMIEQEKEDLEKMKSEIMKQRQQM 1765

Query: 1022 DEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEEL 1081
            +EE   L+ KI    +    +    E  + +   ++E   ++ + ++KQ  + ++  E+L
Sbjct: 1766 EEERSELDNKIQQTNLEKHDIEKSKEI-VEKLMVEVEEQSKQREDLTKQ--EMEEEKEDL 1822

Query: 1082 QILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXX 1141
            + +  E   Q ++++E +   +  I +T+  +    IE   +    V             
Sbjct: 1823 EKMKSEIMTQRQQMEEERSELDNKIKQTD--LERHDIE---NSKEIVQKLMVKVEEQRKD 1877

Query: 1142 LKVQEEEEFIQERSVLQEQSAKLNTE--LQECYTKIIQLETLNTELTGHDVVNQEQINQL 1199
            +++Q+EE  I+ + +  EQ   +  +  LQ    +I +++    +    D+  Q+++ + 
Sbjct: 1878 IRLQKEELDIERQKIADEQGLVVQNKAKLQNENERIKEMDEEINKQKEEDLTKQKKMEEE 1937

Query: 1200 KSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELW--KQHLAQREADFQKTEHEL 1257
            K  LE++ +E       + E RS + + + Q   E  ++   K+ + +   + ++   ++
Sbjct: 1938 KEDLEKMKSEIMKQRQQMEEERSELDNKIKQTDLERHDIENSKEIVQKLMVEVEEQRKDI 1997

Query: 1258 RVQLSAFESKYEQLLDS----VQSST--QEETNKIVTM-EQVTSLQNKLQDKEEHLRNLQ 1310
            R+Q    + + +++ D     VQ+    Q E  +I  M E++   +  L++ E HLR  +
Sbjct: 1998 RLQKEELDIERQKIADEQGLVVQNKAKLQNENERIKEMDEEIKKEKETLKEMEAHLRKEK 2057

Query: 1311 EKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNI 1370
            E+   VI + +  + E  ++K                   DL  +N+S  Q + + I NI
Sbjct: 2058 EEMRSVIEETQRRQKEDLEKKEELDIERQKIADEQ-----DLLIQNKSELQNENERIKNI 2112

Query: 1371 NEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQR 1430
            NE    +KK               + + + K  +L  + E+K+    +K+ E T      
Sbjct: 2113 NEV---IKKERET-----------LKEIKQKEEDLPKEKEMKED---RKSLEETKA---- 2151

Query: 1431 NDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEE 1490
                 N+ +   + E   E++  EKE E     +++       E  Q +S++ER + ++ 
Sbjct: 2152 -----NILEMKTKAEP--EEIKKEKEKEEEEQEMRVKVEMERKEIEQIKSQLERKEELDI 2204

Query: 1491 LNVKITE 1497
               KI +
Sbjct: 2205 ERQKIAD 2211



 Score =  135 bits (326), Expect = 1e-29
 Identities = 191/963 (19%), Positives = 431/963 (44%), Gaps = 90/963 (9%)

Query: 664  LEEQIDALSASKKELALVIENLKLDKEQLYGTI----KDLENDKEDI------MNKLQNY 713
            +E++      S+K L   ++ +KL K+++   I    +D+EN KE I      + +LQ  
Sbjct: 1    MEKEKHDFDQSRKSLDEDLKMMKLQKQEMRENISKQTEDVENKKEKIRLREEKLKQLQAE 60

Query: 714  IQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDL-YIENIESELS 772
            I +    T+K EK + E+    + K   + Q++      +D +  E +   ++ +++EL 
Sbjct: 61   IHKQQSETEK-EKSNIERERAAIIKDVEDLQNRDAESLKLDREAFENEKEELKQMKTELE 119

Query: 773  KYKSRICRLEESIAVMEDRRYSLERKAD---QLGSYLQEKQKAYSEYTIQEDELVNRLAV 829
            +    I +++  +    +R+   E  AD    + +  +E Q          +EL      
Sbjct: 120  READEIEKIK--LETQHERQRVEEMTADFMETMNNIKEETQNERQRLEKMTEELKKEKES 177

Query: 830  L--MDHDRVVEKQLLE---IEHEN--KELQKKNQILLEENQNLQISLSDMQQHYNALVEK 882
               +  D   EK++L+   + +E+   +LQK+   L E  +N+     D ++    +  +
Sbjct: 178  FTHLAEDTKTEKKILDKMKVANESLMADLQKEKSNLEEMRENISKQTEDSEKEKEKIRLR 237

Query: 883  ANRTDLAESESTKYQTQLRDLESNLK---RITHEHQTLIVQK-KKEIEDLEIEFNTQIES 938
             +  +  ++E  K Q +++  +SN +   +I  E + + ++K K+EI++         E+
Sbjct: 238  EDELEQLQAEIHKQQGEIKMEKSNNEKQMKIELEREAVEIRKIKEEIQNERQNLEKMTEA 297

Query: 939  AIRDKKVLNEKYE--KNIEYVTQLEAQLQEYKNNIENLNMNV-EELNKMNLELIDKHVQK 995
               +++    + E  K ++   + EA++Q+ + ++E +N N+  E++++      KH ++
Sbjct: 298  LKEEREAFENEKEVLKQMKTELEREAEIQKEREDLEKMNENITREMHEI------KHQEE 351

Query: 996  QQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTT 1055
            Q  Q  D  +Q   EI  L   L +K++EII  ++          S +   +S+L +  T
Sbjct: 352  QMNQKQDELDQLKTEIQNLQQEL-EKEKEIIMKDR----------SQLDLRQSELDKQQT 400

Query: 1056 KLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIIS 1115
             + ++ E M+   KQL   K+  EE +  + ++ ++  +L++ K+  E      E   IS
Sbjct: 401  NMNDIMETMKNERKQLDKDKEEMEEQKQEMEKEREEKNKLEQMKIELE-----READEIS 455

Query: 1116 STIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQE--QSAKLNTELQECYT 1173
               E   +    ++            +K  + +  IQ   +++E  +  K NT L E   
Sbjct: 456  KIKEETQNKRQRLEKMTEAFENEKEAMKQMKTDLQIQADEIVKEDLEKQKENT-LAEIQK 514

Query: 1174 KIIQLETLNTELTG--HDVVNQ-EQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQ 1230
            +   +E +N  +T   H++ +Q EQ+NQ + +L+QL TE  NL   + + +  I     Q
Sbjct: 515  EREDVEKMNENITREMHEIKHQEEQMNQKQDELDQLKTEIQNLQQELEKEKEIIMKDRSQ 574

Query: 1231 RGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQ--EETNKIVT 1288
                 +EL KQ       D  +T    R QL   + + E+    ++      +++ K + 
Sbjct: 575  FDLRQSELDKQQTNMN--DIMETMKNERKQLDKDKEEMEEQKQEMEKEKHDFDQSRKSLD 632

Query: 1289 ME-QVTSLQNKLQDKEEH-LRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXX 1346
             + ++  LQ ++ ++E++ L  ++ +     ++I  ++ E ++E+ +             
Sbjct: 633  KDLKMMKLQKQVFEEEKNKLEQMKIELEREADEIRKIKEETQNERQSL-EKMTEELKKEK 691

Query: 1347 XXXXDLRTENQSYKQMQEQSILNINE--ENAQLKKSSXXXXXXXXXXXXRVNDAEA---K 1401
                 L    +  ++ +E ++  I +  E+  L+K              +  D E    K
Sbjct: 692  ESFTHLAEVKEDLEKQKENTLAQIQKEREDLDLQKEKSNLEEMKENISKQTEDIEKEKDK 751

Query: 1402 VLELTHQLELKDSEIYQKTHEYTITLTQRNDE-------FENVRQQLVEYEKRIEDLTYE 1454
            +     +LE   +EI+++  E  I  +    E        E+++ +++  ++  E L  +
Sbjct: 752  IRLREDELEQLQAEIHKQQSETEIEKSNIERERAAIIKDVEDLQSKIISLDRDAESLKLD 811

Query: 1455 KES------ELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAEL 1508
            +E+      EL  ++ ++   A+  E ++ E++ ER + +EE+     E+++  ++  + 
Sbjct: 812  REAFENEKEELKQMKTELEREADEIEKIKLETQHERQR-VEEMTADFMETMNNERKQLDK 870

Query: 1509 NKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGR 1568
            NK + EE  +  EM+   ++ +    +L++++  ++    +  +K+Q+ +      +Q  
Sbjct: 871  NKVMIEE--QKQEMEKKRDDMDQSRKSLDEDLKMMKAQKESELAKLQEDI---LQQQQEM 925

Query: 1569 DEQ 1571
            DEQ
Sbjct: 926  DEQ 928



 Score =  107 bits (256), Expect = 3e-21
 Identities = 169/885 (19%), Positives = 391/885 (44%), Gaps = 87/885 (9%)

Query: 215  KQQMTKMQENFIAMEAEWKDEKQRLLKDIE---SKDVRISSLEEANKLLEAARFEISLEH 271
            ++++ + QE    M+ +   ++    K++E   S+  ++  L+E  K L+ A+ E     
Sbjct: 1353 REELQREQEALEVMKVDILKKRNEFAKEMENVHSERQKLLLLQE-QKHLKQAKAETEECR 1411

Query: 272  SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELL 331
             +LA+  E               L ++  +    +    +EK  L+        K+ E L
Sbjct: 1412 KQLAEMSETVTTEQNEYRKLIEELQREKEQLEISKNQIEQEKKDLQNMKSNLERKEREDL 1471

Query: 332  EHLNCQIRQTNKELEN---KLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQ 388
            E+   +I    K +E    +L     E K V S  +K    +  +    T  K ++   +
Sbjct: 1472 ENCWVEIEGEKKRMEEETRRLEMHREEIKKVDSELQKKKKELEDQMMDLTREKQETEEER 1531

Query: 389  LSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTL 448
             +   L    +    +NEI K ++ ++  N + +  + +  ++             K++L
Sbjct: 1532 NNLMALKNQLEDLRKENEIVKEKLTLEKSNIEEMQLK-IFKQQRLNDQTREENKKEKESL 1590

Query: 449  IAQLQLEHQQHMEGPSLIHVGTNT--EDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLK 506
              Q + E +Q  +   ++ + T    E+ NE+A +  +L Q+  DE++ +  K   E+  
Sbjct: 1591 -EQQRFETEQQKQ---MLEISTTKMMEEKNEMADLSREL-QKAKDELEKIAYKTNKER-H 1644

Query: 507  SAEEQITQLNDEIDAANKN--MIKVKSNH----KLKLKQMQKTIDNFSKVSDSNKEIVR- 559
              E+   +L+ +I A  +   +++ K NH    +L +++ ++  ++  K+S   KE  + 
Sbjct: 1645 EVEQMQAELHSQIQAIEQQGQIMQDKQNHLEEKELSIQKTRRQKEDLEKMSTDIKEQNQD 1704

Query: 560  LTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIE-----MENLAETRLK 614
            L ++   L Q+  +++ E   ++   +D++  ++ +   Y KMIE     +E +    +K
Sbjct: 1705 LMKQRDLLEQEKEDIKSELERVRSE-IDHEQKKLND---YMKMIEQEKEDLEKMKSEIMK 1760

Query: 615  AISLLESQKFDL---VQELHILQ---QKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQI 668
                +E ++ +L   +Q+ ++ +   +K  E+ +KL    + QS Q   ++    +EE+ 
Sbjct: 1761 QRQQMEEERSELDNKIQQTNLEKHDIEKSKEIVEKLMVEVEEQSKQR-EDLTKQEMEEEK 1819

Query: 669  DALSASKKELALVIENLKLDKEQLYGTIK-------DLENDKEDIMNKLQNYIQENMDLT 721
            + L   K E+    + ++ ++ +L   IK       D+EN KE +   +    ++  D+ 
Sbjct: 1820 EDLEKMKSEIMTQRQQMEEERSELDNKIKQTDLERHDIENSKEIVQKLMVKVEEQRKDIR 1879

Query: 722  DKLEKMSAEK-----------------------ISELLAKINHEEQSKIQTQFGIDAKIQ 758
             + E++  E+                       I E+  +IN +++  +  Q     K++
Sbjct: 1880 LQKEELDIERQKIADEQGLVVQNKAKLQNENERIKEMDEEINKQKEEDLTKQ----KKME 1935

Query: 759  ERDLYIENIESELSKYKSRI----CRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYS 814
            E    +E ++SE+ K + ++      L+  I   +  R+ +E   + +   + E ++   
Sbjct: 1936 EEKEDLEKMKSEIMKQRQQMEEERSELDNKIKQTDLERHDIENSKEIVQKLMVEVEEQRK 1995

Query: 815  EYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQ 874
            +  +Q++EL      + D   +V +   ++++EN+ +++ ++ + +E + L+   + +++
Sbjct: 1996 DIRLQKEELDIERQKIADEQGLVVQNKAKLQNENERIKEMDEEIKKEKETLKEMEAHLRK 2055

Query: 875  HYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNT 934
                +      T   + E  + + +L D+E   ++I  E Q L++Q K E+++       
Sbjct: 2056 EKEEMRSVIEETQRRQKEDLEKKEEL-DIER--QKIADE-QDLLIQNKSELQNENERIKN 2111

Query: 935  QIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEEL-NKMNLELIDKHV 993
              E   ++++ L E  +K  E     E +++E + ++E    N+ E+  K   E I K  
Sbjct: 2112 INEVIKKERETLKEIKQK--EEDLPKEKEMKEDRKSLEETKANILEMKTKAEPEEIKKEK 2169

Query: 994  QKQQTQSP--DYTEQYINEINKLNALLKQKDEEIIALNQKINNAQ 1036
            +K++ +       E    EI ++ + L++K EE+    QKI + Q
Sbjct: 2170 EKEEEEQEMRVKVEMERKEIEQIKSQLERK-EELDIERQKIADEQ 2213


>UniRef50_UPI00006CD140 Cluster: Viral A-type inclusion protein repeat
            containing protein; n=1; Tetrahymena thermophila
            SB210|Rep: Viral A-type inclusion protein repeat
            containing protein - Tetrahymena thermophila SB210
          Length = 2937

 Score =  170 bits (414), Expect = 2e-40
 Identities = 266/1391 (19%), Positives = 590/1391 (42%), Gaps = 93/1391 (6%)

Query: 213  DTKQQMTKMQENFIAMEAEWKDEKQRLLKDIES----KDVRISSLEEANKLLEAARFEIS 268
            + K+Q  K +E  +A + E+  EK   + D E     K+  + SL E  K  E     + 
Sbjct: 864  EQKEQHVKEREETLAQQIEFLKEKDIYVNDREQELLDKERELESLFEEQKEKEKYLENLI 923

Query: 269  LEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKI 328
             E ++  + LEQ              L +Q       EK ++ E+  +   N  E  K +
Sbjct: 924  NEQNQKLKLLEQQSINQQSEDLK---LLEQQFINEQNEKLKLLEQQLINEQN--EKLKNL 978

Query: 329  ELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQ 388
            E  E L  +  +  K LE +L     + KA+    K+      ++   +     ++   Q
Sbjct: 979  E--EKLVNEQNEKLKLLEQQLDEHQAKEKALEQLLKEND---GKQKELDLLISQQAEKEQ 1033

Query: 389  LSSETLNQDTDKKINKNEIA-KLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDT 447
            +  + + Q   ++    +I  + +   Q L +   ++  +  + +             D 
Sbjct: 1034 VLQQLMEQQKQREYEFEQIVNEQKQKEQELEQLFSEQSKIKHQLEQQLAQQIEKEQELDQ 1093

Query: 448  LIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKS 507
            LI + Q  +Q        I + T  ++  +   VQE   ++   E  D N ++L  +LK 
Sbjct: 1094 LINEAQSRNQATFTEEQEIVLTTPKKEERQERTVQEGRNEDFT-EGNDENEEELELRLKK 1152

Query: 508  AEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHL 567
              E + Q   +I +A KN    K     K+  ++K + N+  +    K    +  +   L
Sbjct: 1153 EVEDLQQ-QLQI-SAQKNQESAK-----KIIDLEKAVQNYQMIERDEKNFEEIFRQNKKL 1205

Query: 568  SQKVAELEEEKGNLQLHLVDYDSG-RMIESDVYKKMIEMENLAETRLKAISLLESQKFDL 626
              K+   E E    +  L   +     + S + +   +++   E +      +E+ K++ 
Sbjct: 1206 EDKIKSYEMEYSARKNQLEHQEQTIAKLHSQLVQADADLQKYIEDKRLLNDKIEALKYEK 1265

Query: 627  VQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLK 686
             +E+  L+Q+ D  +   +    ++S+ +  E      ++ I+ LS   ++    I+NL 
Sbjct: 1266 EEEIKRLKQENDIEKMSRSQSKLMESESIAFESIVGDYKDTINMLSNKCEDYETQIQNLT 1325

Query: 687  LDKEQLYGTIKDLEND----KEDIMNK---LQNYIQENMDLTDKLE--KMSAEKISELLA 737
                 L  + K+++++    +E++ NK   +Q   Q+  +L   +   K  A+K+ + L 
Sbjct: 1326 KQNNVLVNSFKEIKSNLTSYQEELDNKEEFIQKQSQDMFELQKSVNQYKQMAKKLEDQLK 1385

Query: 738  KINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLER 797
             ++++ Q +  T   +  ++++ ++ +E    ++      I  L E I+++E       +
Sbjct: 1386 DLSNKSQEESST---LQYELEKNNILLEQKNKDVQAKNQEIQSLYEKISLIEKSNL---Q 1439

Query: 798  KADQLGSYLQEKQKAYSEYTIQEDELVNRLAV-LMDHDRVVEKQLLEIEHENKELQKKNQ 856
            K + L   +QE+Q    E   + ++LV++    + +  +V+++Q  E     ++LQ+ +Q
Sbjct: 1440 KLEDLNLVIQEEQNQRKEIQTELEQLVDKYNQDVQELQKVMDQQQEEFTQIQQQLQESSQ 1499

Query: 857  ILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQT 916
               +EN NL+  +  ++Q    L +K       + E    +  L+ +E++LK+  HE   
Sbjct: 1500 NQQKENLNLKEQMEHLKQQ---LDQKNAEIVSKQEELLNLEDMLQKIENDLKQQKHEFD- 1555

Query: 917  LIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYK--NNIENL 974
            L +QK+++  +  ++   +I    +++  L ++ +++    +Q + ++ + K  N +  L
Sbjct: 1556 LQIQKQEDSNNQHVDQLQKIIDEKQEEISLLQQNQQDSSLRSQEDLKILKIKLDNLVSEL 1615

Query: 975  NMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINN 1034
            N   E+LN+M+ EL  K  Q + T+     ++Y   IN+L   +KQ D     L  +   
Sbjct: 1616 NNANEQLNEMDKELQFKDEQLKLTE-----KEYQMNINQLQ--VKQND-----LQDQKKQ 1663

Query: 1035 AQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKE 1094
             +         Y  ++ Q    ++  +E++Q + + LL S +  E+    +  +  Q K+
Sbjct: 1664 LEEMLQEQEERYSQEITQLQNIIDQQQEDLQGLQQNLLGSSKIQEDKNKALTNELQQAKQ 1723

Query: 1095 LKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQER 1154
              E K+  ++     +        +  S+  N                K ++ +E IQ  
Sbjct: 1724 EIE-KMNHQLQAQHKDLEKAYQQFDD-SEKQNQQKLKSAEVKLQDLEAKYKDLQESIQ-- 1779

Query: 1155 SVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLL 1214
             + QE+ +K   ELQ     II+ +     L   ++   +  N L  K++ L+ +N  + 
Sbjct: 1780 -IEQEKYSKDIEELQN----IIETQQQEINLMEQNMTKLK--NDLDRKVKDLDVKNIEIQ 1832

Query: 1215 STVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDS 1274
            +  ++L S+ +  +D+   +      ++ ++++ +     + L  +L   E KY + +  
Sbjct: 1833 AKDSDLESAYAQ-IDKIDIQYQHKLNEYESKQQ-ELANNNNHLEGKLIELEDKYNKDVSE 1890

Query: 1275 VQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQ--IEILRSEIEDEKV 1332
            +Q   +++   +  +EQ    Q    ++  +LR   EK +  +++   EIL    E + +
Sbjct: 1891 LQKVIEQQQQDLNNLEQELYNQGSQNEETSNLRVELEKVSIQLDERNSEILIKNKELDSM 1950

Query: 1333 AFXXXXXXXXXXXXXXXXDLRTEN-QSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXX 1391
                              +++ ++ Q  K+  +Q +L ++ +N+Q               
Sbjct: 1951 YEQIDKIERQYQQKLREQEIKIQDLQKLKKEYDQQLLELDNKNSQ---DIADLKNIIEQQ 2007

Query: 1392 XXRVNDAEAKVLELT-HQLELKDS--EIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRI 1448
               +N+ +  + E T HQ E  +   E+ +K  +    L Q+N E + + +Q+ + EK+ 
Sbjct: 2008 QEDLNNMQKDLFENTKHQEENNNLRFELERKNIQLNSDLIQKNKELDQLHEQINKIEKQN 2067

Query: 1449 EDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAE- 1507
            +    ++E       LK+ +  N     +KE +++ ++  E+ N  ITE   + +Q  E 
Sbjct: 2068 QQKLRDQE-------LKLQDLQNQ----KKEFDLKLMEQEEKNNQYITELQKIIEQQQED 2116

Query: 1508 LNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQG 1567
            LNK +E+ + + N  Q  + N   EI    +E+    N +     +++       + ++ 
Sbjct: 2117 LNK-MEQCLYENNGSQDEINNLRSEIEKQQNELDEKSNEINQKEKELEDMFQQMQEVERQ 2175

Query: 1568 RDEQLDNTMNK 1578
              ++L+ T +K
Sbjct: 2176 YQDKLNETESK 2186



 Score =  167 bits (407), Expect = 2e-39
 Identities = 292/1510 (19%), Positives = 644/1510 (42%), Gaps = 142/1510 (9%)

Query: 164  KMKIMETTILDLQ-EKI-NEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKM 221
            K+K++E  +++ Q EK+ N +++++  +N+                    +  K+   K 
Sbjct: 959  KLKLLEQQLINEQNEKLKNLEEKLVNEQNEKLKLLEQQLDEHQAKEKALEQLLKENDGKQ 1018

Query: 222  QEN--FIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELE 279
            +E    I+ +AE +   Q+L++  + ++     +    K  E    ++  E SK+  +LE
Sbjct: 1019 KELDLLISQQAEKEQVLQQLMEQQKQREYEFEQIVNEQKQKEQELEQLFSEQSKIKHQLE 1078

Query: 280  QXXXXXXXXXXXXXXLA-------------KQSIEPSCEEKTEIEEKGSLEIANMTELTK 326
            Q              L              +Q I  +  +K E +E+   E  N      
Sbjct: 1079 QQLAQQIEKEQELDQLINEAQSRNQATFTEEQEIVLTTPKKEERQERTVQEGRNEDFTEG 1138

Query: 327  KIELLEHLNCQIRQTNKELENKL---ATMGTES--KAVSSPSKKGSPLISRKSGRNTASK 381
              E  E L  ++++  ++L+ +L   A    ES  K +       +  +  +  +N    
Sbjct: 1139 NDENEEELELRLKKEVEDLQQQLQISAQKNQESAKKIIDLEKAVQNYQMIERDEKNFEEI 1198

Query: 382  MKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLV----DKEYVISEKDTXXXX 437
             +    +L  +  + + +    KN++   E  I  L+  LV    D +  I +K      
Sbjct: 1199 FRQN-KKLEDKIKSYEMEYSARKNQLEHQEQTIAKLHSQLVQADADLQKYIEDKRLLNDK 1257

Query: 438  XXXXXXGKDTLIAQLQLEHQ---------QHMEGPSLIH---VGTNTEDVNEIAKVQEQL 485
                   K+  I +L+ E+          + ME  S+     VG   + +N ++   E  
Sbjct: 1258 IEALKYEKEEEIKRLKQENDIEKMSRSQSKLMESESIAFESIVGDYKDTINMLSNKCEDY 1317

Query: 486  KQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTID 545
            + ++ +  K  NV  L+   K  +  +T   +E+D  NK     K +  +   ++QK+++
Sbjct: 1318 ETQIQNLTKQNNV--LVNSFKEIKSNLTSYQEELD--NKEEFIQKQSQDMF--ELQKSVN 1371

Query: 546  NFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYD---SGRMIESDVYKKM 602
             + +++   ++ ++             + E EK N+ L   + D     + I+S +Y+K+
Sbjct: 1372 QYKQMAKKLEDQLKDLSNKSQEESSTLQYELEKNNILLEQKNKDVQAKNQEIQS-LYEKI 1430

Query: 603  IEMENLAETRLKAISLL----ESQKFDLVQELHILQQKY-----------DEVEDKLADI 647
              +E     +L+ ++L+    ++Q+ ++  EL  L  KY           D+ +++   I
Sbjct: 1431 SLIEKSNLQKLEDLNLVIQEEQNQRKEIQTELEQLVDKYNQDVQELQKVMDQQQEEFTQI 1490

Query: 648  SQ-LQSDQVCSEIKSVHLEEQIDALSAS--KKELALVIENLKL-DKEQLYGTIK-DLEND 702
             Q LQ      + ++++L+EQ++ L     +K   +V +  +L + E +   I+ DL+  
Sbjct: 1491 QQQLQESSQNQQKENLNLKEQMEHLKQQLDQKNAEIVSKQEELLNLEDMLQKIENDLKQQ 1550

Query: 703  KEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDL 762
            K +   ++Q     N    D+L+K+  EK  E+     +++ S +++Q   D KI +  +
Sbjct: 1551 KHEFDLQIQKQEDSNNQHVDQLQKIIDEKQEEISLLQQNQQDSSLRSQE--DLKILK--I 1606

Query: 763  YIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLG-SYLQEKQKAYSEYTIQED 821
             ++N+ SEL+    ++  +++ +   +D +  L  K  Q+  + LQ KQ    +   Q +
Sbjct: 1607 KLDNLVSELNNANEQLNEMDKELQ-FKDEQLKLTEKEYQMNINQLQVKQNDLQDQKKQLE 1665

Query: 822  ELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVE 881
            E+      L + +    +++ ++++   + Q+  Q L    QNL +  S +Q+  N  + 
Sbjct: 1666 EM------LQEQEERYSQEITQLQNIIDQQQEDLQGL---QQNL-LGSSKIQEDKNKAL- 1714

Query: 882  KANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIR 941
              N    A+ E  K   QL+    +L++   +      Q +++++  E++    +E+  +
Sbjct: 1715 -TNELQQAKQEIEKMNHQLQAQHKDLEKAYQQFDDSEKQNQQKLKSAEVKLQ-DLEAKYK 1772

Query: 942  DK----KVLNEKYEKNIEYVTQ-LEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQ 996
            D     ++  EKY K+IE +   +E Q QE     +N+     +L++   +L  K+++ Q
Sbjct: 1773 DLQESIQIEQEKYSKDIEELQNIIETQQQEINLMEQNMTKLKNDLDRKVKDLDVKNIEIQ 1832

Query: 997  QTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKI----NNAQVSYMSMVSDYESKLAQ 1052
               S D    Y  +I+K++   + K  E  +  Q++    N+ +   + +   Y   +++
Sbjct: 1833 AKDS-DLESAYA-QIDKIDIQYQHKLNEYESKQQELANNNNHLEGKLIELEDKYNKDVSE 1890

Query: 1053 FTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGM 1112
                +E  ++++  + ++L +    NEE   L  E +         K++ +++   +E +
Sbjct: 1891 LQKVIEQQQQDLNNLEQELYNQGSQNEETSNLRVELE---------KVSIQLDERNSEIL 1941

Query: 1113 IISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQE----EEEFIQERSVLQEQSAKLNTEL 1168
            I +  ++ M +  + ++            +K+Q+    ++E+ Q+   L  ++++   +L
Sbjct: 1942 IKNKELDSMYEQIDKIE-RQYQQKLREQEIKIQDLQKLKKEYDQQLLELDNKNSQDIADL 2000

Query: 1169 QECYTKIIQLETLNTELTG--HDVVNQEQINQLKSKLEQLNTE-NDNLLSTVAELRSSIS 1225
            +    +  Q E LN        +  +QE+ N L+ +LE+ N + N +L+    EL     
Sbjct: 2001 KNIIEQ--QQEDLNNMQKDLFENTKHQEENNNLRFELERKNIQLNSDLIQKNKELDQLHE 2058

Query: 1226 SAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNK 1285
                       +L  Q L  ++   QK E +L+  L   E K  Q +  +Q   +++   
Sbjct: 2059 QINKIEKQNQQKLRDQELKLQDLQNQKKEFDLK--LMEQEEKNNQYITELQKIIEQQQED 2116

Query: 1286 IVTMEQVTSLQNKLQDKEEHLRNLQEKYADVI----NQIEILRSEIED---EKVAFXXXX 1338
            +  MEQ     N  QD+  +LR+  EK  + +    N+I     E+ED   +        
Sbjct: 2117 LNKMEQCLYENNGSQDEINNLRSEIEKQQNELDEKSNEINQKEKELEDMFQQMQEVERQY 2176

Query: 1339 XXXXXXXXXXXXDLRTENQ----SYKQMQEQSILNINE------ENAQLKKSSXXXXXXX 1388
                        +L+ +N      +++ +++S  +I+E      +  ++           
Sbjct: 2177 QDKLNETESKLKELQNQNNEIIGKFEESEQKSNFHISELQKIIDQQQEMIGRMDQDLFDT 2236

Query: 1389 XXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRI 1448
                   N    ++   T QLE +++EI  K  E      Q +      +Q+L ++E + 
Sbjct: 2237 SRQQEENNSLRMELERKTLQLEQRNAEILSKNKELESKYDQLDKIERQYQQKLRDFELKQ 2296

Query: 1449 EDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAEL 1508
            +DL  +K+ EL +  L+  EN    E +Q+E E+++ +L   L+ +  E   LN ++   
Sbjct: 2297 QDLQNQKK-ELELRLLEQEENGGSLEKLQREFEMQKKELENILDKQQIEIEELNDKLIRQ 2355

Query: 1509 NKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQ-KHVSFASDTKQG 1567
             +  E ++A+ N     +++ E++  T   ++  LQ  +R  +  ++ K+     D K  
Sbjct: 2356 REDYEYQLAQAN---NRIQSIELDHKTEIKKLMKLQEELRLQNRDMENKYERLKEDHKNI 2412

Query: 1568 RDEQLDNTMN 1577
            ++   +N+ +
Sbjct: 2413 QNSSFNNSFD 2422



 Score =  162 bits (394), Expect = 6e-38
 Identities = 232/1212 (19%), Positives = 531/1212 (43%), Gaps = 83/1212 (6%)

Query: 445  KDTL--IAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNV-KDL 501
            KD L  I   + E QQ      ++ + T  +++ E+  +   LK   N    D  + KD 
Sbjct: 669  KDILNEIKTFKQEKQQKDPEEIVMRLSTLLQEL-EVQNLNNSLKLSQNQIPNDSQIEKDF 727

Query: 502  IEKLKSA--EEQITQLNDEIDAANKNMI-KVKSNHKLKLKQMQKTIDNFSKVSDSNKEIV 558
             +K++++  +E + +   +   A K+ + +     K+  ++ QK  +  +K     +E++
Sbjct: 728  EQKIQASLQKESLKKEEKQNSEAQKDEVTEFNQEDKIDKEEFQKEKEIITK---EKEELI 784

Query: 559  RLTEELHH----LSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLK 614
            +L E+L       +++  E+E++K  L+L   + +   M   +  K++ E++N  + + +
Sbjct: 785  QLKEDLRKQKEDFNKQKQEVEKQKSELELKAENLNLISMQFEEREKELEEVQNTLQQQQE 844

Query: 615  AISLLESQKFDLVQELHILQQKYDEVEDKLADISQ----LQSDQVCSEIKSVHL---EEQ 667
             +S    Q   +  +L +L+QK   V+++   ++Q    L+   +    +   L   E +
Sbjct: 845  ELSQKRKQYEQIQDKLELLEQKEQHVKEREETLAQQIEFLKEKDIYVNDREQELLDKERE 904

Query: 668  IDALSASKKELALVIENLKLDKEQLYGTIKD--LENDKEDIMNKLQNYIQENMDLTDKLE 725
            +++L   +KE    +ENL  ++ Q    ++   +    ED+    Q +I E  +    LE
Sbjct: 905  LESLFEEQKEKEKYLENLINEQNQKLKLLEQQSINQQSEDLKLLEQQFINEQNEKLKLLE 964

Query: 726  KM----SAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRL 781
            +       EK+  L  K+ +E+  K++    ++ ++ E     + +E  L +   +   L
Sbjct: 965  QQLINEQNEKLKNLEEKLVNEQNEKLKL---LEQQLDEHQAKEKALEQLLKENDGKQKEL 1021

Query: 782  EESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQL 841
            +  I+   ++   L++  +Q      E ++  +E   +E EL    +        +E+QL
Sbjct: 1022 DLLISQQAEKEQVLQQLMEQQKQREYEFEQIVNEQKQKEQELEQLFSEQSKIKHQLEQQL 1081

Query: 842  LE-IEHENK------ELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAE-SES 893
             + IE E +      E Q +NQ    E Q + ++    ++     V++    D  E ++ 
Sbjct: 1082 AQQIEKEQELDQLINEAQSRNQATFTEEQEIVLTTPKKEERQERTVQEGRNEDFTEGNDE 1141

Query: 894  TKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIES---AIRDKKVLNEKY 950
             + + +LR L+  ++ +  + Q +  QK +E     I+    +++     RD+K   E +
Sbjct: 1142 NEEELELR-LKKEVEDLQQQLQ-ISAQKNQESAKKIIDLEKAVQNYQMIERDEKNFEEIF 1199

Query: 951  EKNIEYVTQLEAQLQEY---KNNIENLNMNVEELNKMNLEL---IDKHVQKQQTQSPDYT 1004
             +N +   ++++   EY   KN +E+    + +L+   ++    + K+++ ++  +    
Sbjct: 1200 RQNKKLEDKIKSYEMEYSARKNQLEHQEQTIAKLHSQLVQADADLQKYIEDKRLLNDKIE 1259

Query: 1005 EQYINEINKLNALLKQKDEEIIALNQK--INNAQVSYMSMVSDYESKLAQFTTKLENMEE 1062
                 +  ++  L ++ D E ++ +Q   + +  +++ S+V DY+  +   + K E+ E 
Sbjct: 1260 ALKYEKEEEIKRLKQENDIEKMSRSQSKLMESESIAFESIVGDYKDTINMLSNKCEDYET 1319

Query: 1063 EMQRVSKQ---LLDS-KQHNEELQILVREQDDQIKEL-KETKLTFEMNIPKTEGMIISST 1117
            ++Q ++KQ   L++S K+    L     E D++ + + K+++  FE+     +   ++  
Sbjct: 1320 QIQNLTKQNNVLVNSFKEIKSNLTSYQEELDNKEEFIQKQSQDMFELQKSVNQYKQMAKK 1379

Query: 1118 IEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQ 1177
            +E    D +N              L+ + E+  I      ++  AK N E+Q  Y KI  
Sbjct: 1380 LEDQLKDLSN------KSQEESSTLQYELEKNNILLEQKNKDVQAK-NQEIQSLYEKISL 1432

Query: 1178 LETLNTE-LTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIA 1236
            +E  N + L   ++V QE+ NQ K    ++ TE + L+    +    +   +DQ+  E  
Sbjct: 1433 IEKSNLQKLEDLNLVIQEEQNQRK----EIQTELEQLVDKYNQDVQELQKVMDQQQEEFT 1488

Query: 1237 ELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQ 1296
            ++ +Q L +   + QK    L+ Q+   + + +Q    + S  QEE   +  M Q   ++
Sbjct: 1489 QI-QQQLQESSQNQQKENLNLKEQMEHLKQQLDQKNAEIVSK-QEELLNLEDMLQ--KIE 1544

Query: 1297 NKLQDKEEHLRNLQ-EKYADVINQ-IEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRT 1354
            N L+ +++H  +LQ +K  D  NQ ++ L+  I++++                   DL+ 
Sbjct: 1545 NDLK-QQKHEFDLQIQKQEDSNNQHVDQLQKIIDEKQEEISLLQQNQQDSSLRSQEDLKI 1603

Query: 1355 ENQSYKQM-QEQSILN--INEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLEL 1411
                   +  E +  N  +NE + +L+                +N  + K  +L  Q + 
Sbjct: 1604 LKIKLDNLVSELNNANEQLNEMDKELQFKDEQLKLTEKEYQMNINQLQVKQNDLQDQKKQ 1663

Query: 1412 KDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENAN 1471
             +  + ++   Y+  +TQ  +  +  ++ L   ++ +   +  +E +   L  ++ +   
Sbjct: 1664 LEEMLQEQEERYSQEITQLQNIIDQQQEDLQGLQQNLLGSSKIQEDKNKALTNELQQAKQ 1723

Query: 1472 HYETMQKESEIERVKLIEELNVKITESVSLNKQ-VAELNKALEEEVAKTNEMQTALENQE 1530
              E M  + + +  K +E+   +  +S   N+Q +      L++  AK  ++Q   E+ +
Sbjct: 1724 EIEKMNHQLQAQH-KDLEKAYQQFDDSEKQNQQKLKSAEVKLQDLEAKYKDLQ---ESIQ 1779

Query: 1531 IEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELD 1590
            IE    + +I  LQN++     +I       +  K   D ++ +   K +      ++L+
Sbjct: 1780 IEQEKYSKDIEELQNIIETQQQEINLMEQNMTKLKNDLDRKVKDLDVKNIEIQAKDSDLE 1839

Query: 1591 LAMYMLHQRDVR 1602
             A   + + D++
Sbjct: 1840 SAYAQIDKIDIQ 1851



 Score =  152 bits (369), Expect = 7e-35
 Identities = 218/1178 (18%), Positives = 495/1178 (42%), Gaps = 75/1178 (6%)

Query: 174  DLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWK 233
            D+++    + +++E+++ A                   ED + Q+  + +    +   +K
Sbjct: 1277 DIEKMSRSQSKLMESESIAFESIVGDYKDTINMLSNKCEDYETQIQNLTKQNNVLVNSFK 1336

Query: 234  DEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXX 293
            + K  L    E  D +   +++ ++ +   +  ++ ++ ++A++LE              
Sbjct: 1337 EIKSNLTSYQEELDNKEEFIQKQSQDMFELQKSVN-QYKQMAKKLEDQLKDLSNKSQEES 1395

Query: 294  XLAKQSIEPS---CEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQ-IRQTN---KELE 346
               +  +E +    E+K +  +  + EI ++ E   KI L+E  N Q +   N   +E +
Sbjct: 1396 STLQYELEKNNILLEQKNKDVQAKNQEIQSLYE---KISLIEKSNLQKLEDLNLVIQEEQ 1452

Query: 347  NKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNE 406
            N+   + TE + +     +    + +   +    +      QL   + NQ  +    K +
Sbjct: 1453 NQRKEIQTELEQLVDKYNQDVQELQKVMDQQQ-EEFTQIQQQLQESSQNQQKENLNLKEQ 1511

Query: 407  IAKLEMVIQSLNKDLVDK-EYVISEKDTXXXXXXXXXXGKDTLIAQLQLE---HQQHMEG 462
            +  L+  +   N ++V K E +++ +D            K     Q+Q +   + QH++ 
Sbjct: 1512 MEHLKQQLDQKNAEIVSKQEELLNLEDMLQKIENDLKQQKHEFDLQIQKQEDSNNQHVDQ 1571

Query: 463  PSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVK--DLIEKLKSAEEQITQLNDEID 520
               I +    E+++ + + Q+       +++K + +K  +L+ +L +A EQ+ +++ E+ 
Sbjct: 1572 LQKI-IDEKQEEISLLQQNQQDSSLRSQEDLKILKIKLDNLVSELNNANEQLNEMDKELQ 1630

Query: 521  AANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIV-----RLTEELHHLSQKVAELE 575
              ++ +   +  +++ + Q+Q   ++        +E++     R ++E+  L   + + +
Sbjct: 1631 FKDEQLKLTEKEYQMNINQLQVKQNDLQDQKKQLEEMLQEQEERYSQEITQLQNIIDQQQ 1690

Query: 576  EEKGNLQLHL-----VDYDSGRMIESDVYKKMIEMENLAETRLKAISLLES--QKFDLVQ 628
            E+   LQ +L     +  D  + + +++ +   E+E +          LE   Q+FD  +
Sbjct: 1691 EDLQGLQQNLLGSSKIQEDKNKALTNELQQAKQEIEKMNHQLQAQHKDLEKAYQQFDDSE 1750

Query: 629  ELHILQQKYDEVEDKLADISQLQSD-----QVCSEIKSVHLEEQIDALSASKKELALVIE 683
            + +  QQK    E KL D+     D     Q+  E  S  +EE  + +   ++E+ L+ +
Sbjct: 1751 KQN--QQKLKSAEVKLQDLEAKYKDLQESIQIEQEKYSKDIEELQNIIETQQQEINLMEQ 1808

Query: 684  NLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKI---- 739
            N+   K  L   +KDL+    +I  K  + ++      DK++     K++E  +K     
Sbjct: 1809 NMTKLKNDLDRKVKDLDVKNIEIQAK-DSDLESAYAQIDKIDIQYQHKLNEYESKQQELA 1867

Query: 740  ---NHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLE 796
               NH E   I+ +   +  + E    IE  + +L+  +  +           + R  LE
Sbjct: 1868 NNNNHLEGKLIELEDKYNKDVSELQKVIEQQQQDLNNLEQELYNQGSQNEETSNLRVELE 1927

Query: 797  RKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKK-- 854
            + + QL        +  SE  I+  EL +    +   +R  +++L E E + ++LQK   
Sbjct: 1928 KVSIQL-------DERNSEILIKNKELDSMYEQIDKIERQYQQKLREQEIKIQDLQKLKK 1980

Query: 855  --NQILLE-ENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRIT 911
              +Q LLE +N+N Q  ++D++       E  N       E+TK+Q +  +L   L+R  
Sbjct: 1981 EYDQQLLELDNKNSQ-DIADLKNIIEQQQEDLNNMQKDLFENTKHQEENNNLRFELERKN 2039

Query: 912  HEHQTLIVQKKKEIEDLEIEFNT---QIESAIRDKKVL-----NEKYEKNIEYVTQLEAQ 963
             +  + ++QK KE++ L  + N    Q +  +RD+++      N+K E +++ + Q E  
Sbjct: 2040 IQLNSDLIQKNKELDQLHEQINKIEKQNQQKLRDQELKLQDLQNQKKEFDLKLMEQEEKN 2099

Query: 964  LQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQS-PDYTEQYINEINKLNALLKQKD 1022
             Q      + +    E+LNKM   L + +  + +  +     E+  NE+++ +  + QK+
Sbjct: 2100 NQYITELQKIIEQQQEDLNKMEQCLYENNGSQDEINNLRSEIEKQQNELDEKSNEINQKE 2159

Query: 1023 EEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEM-QRVSKQLLDSKQHNEEL 1081
            +E+  + Q++   +  Y   +++ ESKL +    L+N   E+  +  +    S  H  EL
Sbjct: 2160 KELEDMFQQMQEVERQYQDKLNETESKLKE----LQNQNNEIIGKFEESEQKSNFHISEL 2215

Query: 1082 QILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXX 1141
            Q ++ +Q + I  + +          +   + +    + +  +  N +            
Sbjct: 2216 QKIIDQQQEMIGRMDQDLFDTSRQQEENNSLRMELERKTLQLEQRNAEILSKNKELESKY 2275

Query: 1142 LKVQE-EEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLK 1200
             ++ + E ++ Q+    + +   L  + +E   ++++ E     L       + Q  +L+
Sbjct: 2276 DQLDKIERQYQQKLRDFELKQQDLQNQKKELELRLLEQEENGGSLEKLQREFEMQKKELE 2335

Query: 1201 SKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQ 1260
            + L++   E + L   +   R      + Q    I  +   H  + +    K + ELR+Q
Sbjct: 2336 NILDKQQIEIEELNDKLIRQREDYEYQLAQANNRIQSIELDHKTEIKK-LMKLQEELRLQ 2394

Query: 1261 LSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNK 1298
                E+KYE+L +  ++      N            NK
Sbjct: 2395 NRDMENKYERLKEDHKNIQNSSFNNSFDANNKLGTPNK 2432



 Score =  152 bits (368), Expect = 9e-35
 Identities = 244/1268 (19%), Positives = 539/1268 (42%), Gaps = 98/1268 (7%)

Query: 380  SKMKSPWSQLSSETLNQDTDKKINK-NEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXX 438
            S+++  + Q    +L +++ KK  K N  A+ + V +   +D +DKE    EK+      
Sbjct: 721  SQIEKDFEQKIQASLQKESLKKEEKQNSEAQKDEVTEFNQEDKIDKEEFQKEKEIITKEK 780

Query: 439  XXXXXGKDTLIAQLQLEHQQHME-GPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVN 497
                  K+ L  Q +  ++Q  E       +    E++N I+   E+ ++EL +E+++  
Sbjct: 781  EELIQLKEDLRKQKEDFNKQKQEVEKQKSELELKAENLNLISMQFEEREKEL-EEVQNT- 838

Query: 498  VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEI 557
            ++   E+L    +Q  Q+ D+++   +    VK   +   +Q++   +    V+D  +E+
Sbjct: 839  LQQQQEELSQKRKQYEQIQDKLELLEQKEQHVKEREETLAQQIEFLKEKDIYVNDREQEL 898

Query: 558  VRLTEELHHLSQKVAELEEEKGNL------QLHLVDYDSGRMIESDVYKKMIEMENLAET 611
            +    EL  L ++  E E+   NL      +L L++  S      D+  K++E + + E 
Sbjct: 899  LDKERELESLFEEQKEKEKYLENLINEQNQKLKLLEQQSINQQSEDL--KLLEQQFINEQ 956

Query: 612  RLKAISLLESQKFDLVQE-LHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDA 670
              K + LLE Q  +   E L  L++K    +++   + + Q D+   + K   LE+ +  
Sbjct: 957  NEK-LKLLEQQLINEQNEKLKNLEEKLVNEQNEKLKLLEQQLDE--HQAKEKALEQLLKE 1013

Query: 671  LSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAE 730
                +KEL L+I   + +KEQ+   + + +  +E    + +  + E      +LE++ +E
Sbjct: 1014 NDGKQKELDLLISQ-QAEKEQVLQQLMEQQKQRE---YEFEQIVNEQKQKEQELEQLFSE 1069

Query: 731  KISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMED 790
            + S++  ++  +   +I+ +  +D  I E     +   +E  +      + EE     ++
Sbjct: 1070 Q-SKIKHQLEQQLAQQIEKEQELDQLINEAQSRNQATFTEEQEIVLTTPKKEER----QE 1124

Query: 791  RRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIE----- 845
            R     R  D      + +++       + ++L  +L +    ++   K+++++E     
Sbjct: 1125 RTVQEGRNEDFTEGNDENEEELELRLKKEVEDLQQQLQISAQKNQESAKKIIDLEKAVQN 1184

Query: 846  HENKELQKKN-QILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLE 904
            ++  E  +KN + +  +N+ L+  +   +  Y+A   + N+ +  E    K  +QL   +
Sbjct: 1185 YQMIERDEKNFEEIFRQNKKLEDKIKSYEMEYSA---RKNQLEHQEQTIAKLHSQLVQAD 1241

Query: 905  SNLKRITHEHQTL-----IVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVT- 958
            ++L++   + + L      ++ +KE E   ++    IE   R +  L E      E +  
Sbjct: 1242 ADLQKYIEDKRLLNDKIEALKYEKEEEIKRLKQENDIEKMSRSQSKLMESESIAFESIVG 1301

Query: 959  QLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALL 1018
              +  +    N  E+    ++ L K N  L++   + +   +      Y  E++     +
Sbjct: 1302 DYKDTINMLSNKCEDYETQIQNLTKQNNVLVNSFKEIKSNLT-----SYQEELDNKEEFI 1356

Query: 1019 KQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQ-RVSKQLLDSKQH 1077
            +++ +++  L + +N     Y  M    E +L   + K +     +Q  + K  +  +Q 
Sbjct: 1357 QKQSQDMFELQKSVNQ----YKQMAKKLEDQLKDLSNKSQEESSTLQYELEKNNILLEQK 1412

Query: 1078 NEELQILVREQDDQIKELKET-KLTFEMNIPKTE--GMIISSTIEPMSDDANNVDXXXXX 1134
            N+++Q     ++ +I+ L E   L  + N+ K E   ++I        +    ++     
Sbjct: 1413 NKDVQA----KNQEIQSLYEKISLIEKSNLQKLEDLNLVIQEEQNQRKEIQTELEQLVDK 1468

Query: 1135 XXXXXXXL-KV--QEEEEFIQERSVLQEQSA---KLNTELQECYTKIIQ-LETLNTELTG 1187
                   L KV  Q++EEF Q +  LQE S    K N  L+E    + Q L+  N E+  
Sbjct: 1469 YNQDVQELQKVMDQQQEEFTQIQQQLQESSQNQQKENLNLKEQMEHLKQQLDQKNAEI-- 1526

Query: 1188 HDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQRE 1247
              V  QE++  L+  L+++  END L     E    I    D     + +L K  + +++
Sbjct: 1527 --VSKQEELLNLEDMLQKI--END-LKQQKHEFDLQIQKQEDSNNQHVDQLQKI-IDEKQ 1580

Query: 1248 ADFQKTEHELRVQLSAFESKYE-QLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHL 1306
             +    +     Q S+  S+ + ++L     +   E N     EQ+  +  +LQ K+E L
Sbjct: 1581 EEISLLQQNQ--QDSSLRSQEDLKILKIKLDNLVSELNN--ANEQLNEMDKELQFKDEQL 1636

Query: 1307 RNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQS 1366
            +  +++Y   INQ+++ +++++D+K                    L    Q+    Q++ 
Sbjct: 1637 KLTEKEYQMNINQLQVKQNDLQDQKKQLEEMLQEQEERYSQEITQL----QNIIDQQQED 1692

Query: 1367 ILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTIT 1426
            +  + +    L  SS             +  A+ ++ ++ HQL+ +  ++ +   ++  +
Sbjct: 1693 LQGLQQN---LLGSSKIQEDKNKALTNELQQAKQEIEKMNHQLQAQHKDLEKAYQQFDDS 1749

Query: 1427 LTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKE------- 1479
              Q   + ++   +L + E + +DL    + E       + E  N  ET Q+E       
Sbjct: 1750 EKQNQQKLKSAEVKLQDLEAKYKDLQESIQIEQEKYSKDIEELQNIIETQQQEINLMEQN 1809

Query: 1480 -----SEIER-VKLIEELNVKITESVS-LNKQVAELNKALEEEVAKTNEMQTALENQEIE 1532
                 ++++R VK ++  N++I    S L    A+++K   +   K NE ++  +     
Sbjct: 1810 MTKLKNDLDRKVKDLDVKNIEIQAKDSDLESAYAQIDKIDIQYQHKLNEYESKQQELANN 1869

Query: 1533 IVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDLA 1592
               L  ++  L++      S++QK +          +++L N  ++    +  R EL+  
Sbjct: 1870 NNHLEGKLIELEDKYNKDVSELQKVIEQQQQDLNNLEQELYNQGSQNEETSNLRVELEKV 1929

Query: 1593 MYMLHQRD 1600
               L +R+
Sbjct: 1930 SIQLDERN 1937



 Score =  123 bits (297), Expect = 4e-26
 Identities = 269/1333 (20%), Positives = 572/1333 (42%), Gaps = 127/1333 (9%)

Query: 323  ELTKKIELLEHLNCQIRQTNKELE-NKLATMGTESKAVS--SPSKKGSPLISRKSGRNTA 379
            E  K+ E  + L+    +TN E +  +    G +   +   +PS++    I   S  +  
Sbjct: 248  EKVKESEEGDSLSNNNEKTNFEAQIQQQVDQGDDQHLIKLLNPSEEVEASIKNNSNLHEE 307

Query: 380  SKMKSPWS--QLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISE--KDTXX 435
            +  +S     Q+  E + Q  +++++  +  + E   Q  N   + +   I +  ++   
Sbjct: 308  NLQQSDQKDQQVKGEDIYQGNEEEMSNQDQNQEEANDQLENDSNIQENKSIKQDQEEIKT 367

Query: 436  XXXXXXXXGKDTLIAQLQLEHQQHME--GPSLIHVGTNTEDVN--EIAKVQEQL--KQEL 489
                     +  +  ++Q+E + HME  G   + V    E+ N  E++  +EQ   +Q++
Sbjct: 368  PIKQQEEESQQDIQTEIQVEQENHMEKQGQQQVEVDNKNENSNLEEVSNQEEQSLREQQI 427

Query: 490  NDEIKDV-NVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFS 548
            NDEI  + + K   +K    ++Q  + N + +   ++    + N   + +Q ++      
Sbjct: 428  NDEINQLEDDKHSEQKQFDQDQQSREENIQSEVFKQDRDNHQQNEAQQYQQEEEEEQESL 487

Query: 549  KVSDSNKEIVRLTE--ELHHLSQ-KVAELEE-EKGNLQLHLVDYDSGRMIESDVYKKMIE 604
            K  +   E+ +     EL+  S  + ++  + +K NL     +  S ++  S V      
Sbjct: 488  KQEEYPSELKQSMNDSELYRNSSFENSQFNQYQKDNLHNQEEEQQSPKIGSSSVLNNYKL 547

Query: 605  MENLAETRLKAISLLESQKF-------DLVQELHILQQ------------KYDEVEDKLA 645
             ++ +       S  +S  +       D +QELH  Q+             YD++E    
Sbjct: 548  EDSPSRPAAAGDSRKQSDNYEQDLYYKDHIQELHNQQEYKSEYQPSPQKEDYDDLESDGF 607

Query: 646  DISQL----QSDQVCSEIK-SVHLEEQIDALSA-SKKELALVIENLKLDKEQLYGTIKDL 699
            D  ++    Q+DQ   +    VH+E+ +    A  +  L   + N  ++K+Q   ++ D 
Sbjct: 608  DTLKMNANDQNDQSSHKYGIQVHIEKSLAPEQAVDENNLENNLLN-PIEKKQQIMSLGD- 665

Query: 700  ENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKI-QTQFGIDAKIQ 758
             +  +DI+N+++ + QE      +   M    + + L   N     K+ Q Q   D++I 
Sbjct: 666  -SALKDILNEIKTFKQEKQQKDPEEIVMRLSTLLQELEVQNLNNSLKLSQNQIPNDSQI- 723

Query: 759  ERDLYIENIESELSKYKSRICRLEESIAVMED-RRYSLERKADQLGSYLQEKQKAYSEYT 817
            E+D + + I++ L K   +    + S A  ++   ++ E K D+     +E QK     T
Sbjct: 724  EKD-FEQKIQASLQKESLKKEEKQNSEAQKDEVTEFNQEDKIDK-----EEFQKEKEIIT 777

Query: 818  IQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYN 877
             +++EL+     L        KQ  E+E +  EL+ K      EN NL IS+   ++   
Sbjct: 778  KEKEELIQLKEDLRKQKEDFNKQKQEVEKQKSELELK-----AENLNL-ISMQ-FEEREK 830

Query: 878  ALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIE 937
             L E  N     + E ++ + Q   ++  L+        L+ QK++ +++ E     QIE
Sbjct: 831  ELEEVQNTLQQQQEELSQKRKQYEQIQDKLE--------LLEQKEQHVKEREETLAQQIE 882

Query: 938  SAIRDKKV-LNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQ 996
              +++K + +N++ ++ ++   +LE+  +E K   + L   + E N+  L+L+++    Q
Sbjct: 883  F-LKEKDIYVNDREQELLDKERELESLFEEQKEKEKYLENLINEQNQ-KLKLLEQQSINQ 940

Query: 997  QTQSPDYTEQ-YINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTT 1055
            Q++     EQ +INE N+   LL+Q  + I   N+K+ N +     +V++   KL     
Sbjct: 941  QSEDLKLLEQQFINEQNEKLKLLEQ--QLINEQNEKLKNLE---EKLVNEQNEKLKLLEQ 995

Query: 1056 KLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQ-------IKELKETKLTFE--MNI 1106
            +L+  + + + + + L ++    +EL +L+ +Q ++       +++ K+ +  FE  +N 
Sbjct: 996  QLDEHQAKEKALEQLLKENDGKQKELDLLISQQAEKEQVLQQLMEQQKQREYEFEQIVNE 1055

Query: 1107 PKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXL-KVQEEEEFIQERSVLQEQSAKLN 1165
             K +   +       S   + ++            L ++  E +   + +  +EQ   L 
Sbjct: 1056 QKQKEQELEQLFSEQSKIKHQLEQQLAQQIEKEQELDQLINEAQSRNQATFTEEQEIVLT 1115

Query: 1166 TELQECYTKIIQLETLNTELTGHDVVNQEQIN-QLKSKLEQLNTENDNLLSTVAELRSSI 1224
            T  +E   +    E  N + T  +  N+E++  +LK ++E L  +   L  +  + + S 
Sbjct: 1116 TPKKEERQERTVQEGRNEDFTEGNDENEEELELRLKKEVEDLQQQ---LQISAQKNQESA 1172

Query: 1225 SSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETN 1284
               +D    E A    Q + + E +F++   +          K E  + S +       N
Sbjct: 1173 KKIID---LEKAVQNYQMIERDEKNFEEIFRQ--------NKKLEDKIKSYEMEYSARKN 1221

Query: 1285 KIVTMEQ-VTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXX 1343
            ++   EQ +  L ++L   +  L+   E    + ++IE L+ E ++E++           
Sbjct: 1222 QLEHQEQTIAKLHSQLVQADADLQKYIEDKRLLNDKIEALKYE-KEEEIKRLKQENDIEK 1280

Query: 1344 XXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVND-AEAKV 1402
                    + +E+ +++ +       IN  + + +                VN   E K 
Sbjct: 1281 MSRSQSKLMESESIAFESIVGDYKDTINMLSNKCEDYETQIQNLTKQNNVLVNSFKEIKS 1340

Query: 1403 LELTHQLELKDSEIY-QKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAI 1461
               ++Q EL + E + QK  +    L +  ++++ + ++L   E +++DL+ + + E + 
Sbjct: 1341 NLTSYQEELDNKEEFIQKQSQDMFELQKSVNQYKQMAKKL---EDQLKDLSNKSQEESST 1397

Query: 1462 LRLKMHENANHYETMQKESEIERVKLIEELNVKIT--ESVSLNKQVAELNKALEEEVAKT 1519
            L+ ++ +N    E   K+ + +  + I+ L  KI+  E  +L K + +LN  ++EE  + 
Sbjct: 1398 LQYELEKNNILLEQKNKDVQAKNQE-IQSLYEKISLIEKSNLQK-LEDLNLVIQEEQNQR 1455

Query: 1520 NEMQTALE------NQEI-EIVTLND----EITNLQNMVRASSSKIQKHVSFASDTKQGR 1568
             E+QT LE      NQ++ E+  + D    E T +Q  ++ SS   QK      +  +  
Sbjct: 1456 KEIQTELEQLVDKYNQDVQELQKVMDQQQEEFTQIQQQLQESSQNQQKENLNLKEQMEHL 1515

Query: 1569 DEQLDNTMNKELL 1581
             +QLD   N E++
Sbjct: 1516 KQQLDQ-KNAEIV 1527



 Score =  105 bits (251), Expect = 1e-20
 Identities = 252/1287 (19%), Positives = 513/1287 (39%), Gaps = 94/1287 (7%)

Query: 370  ISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVIS 429
            I++ S R      +  +SQ   + + Q+T K   +NE    +   Q  ++   ++E    
Sbjct: 165  INQSSSRKDTQNSERLYSQGDEDFVQQNTQKHQQENESIFYKQRNQPDDQQSQEQE---- 220

Query: 430  EKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQEL 489
            +K              D    +   ++++  E      +  N E  N  A++Q+Q+ Q  
Sbjct: 221  QKQQDEIIAFNQEENVDNQNKEQDADNEKVKESEEGDSLSNNNEKTNFEAQIQQQVDQGD 280

Query: 490  NDE-IKDVN----VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTI 544
            +   IK +N    V+  I+   +  E+  Q +D+ D   K     + N +    Q Q   
Sbjct: 281  DQHLIKLLNPSEEVEASIKNNSNLHEENLQQSDQKDQQVKGEDIYQGNEEEMSNQDQNQE 340

Query: 545  D-NFSKVSDSN-KEIVRLTEELHHLSQKVAELEEE-KGNLQLHLVDYDSGRMIESDVYKK 601
            + N    +DSN +E   + ++   +   + + EEE + ++Q  +       M +    ++
Sbjct: 341  EANDQLENDSNIQENKSIKQDQEEIKTPIKQQEEESQQDIQTEIQVEQENHMEKQG--QQ 398

Query: 602  MIEMENLAE-TRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSE-- 658
             +E++N  E + L+ +S  E Q    ++E  I  +     +DK ++  Q   DQ   E  
Sbjct: 399  QVEVDNKNENSNLEEVSNQEEQS---LREQQINDEINQLEDDKHSEQKQFDQDQQSREEN 455

Query: 659  IKSVHLEEQID---ALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQ 715
            I+S   ++  D      A + +     E   L +E+    +K   ND E   N      Q
Sbjct: 456  IQSEVFKQDRDNHQQNEAQQYQQEEEEEQESLKQEEYPSELKQSMNDSELYRNSSFENSQ 515

Query: 716  ENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYK 775
             N    D L     E+ S  +   +     K++      A   +     +N E +L  YK
Sbjct: 516  FNQYQKDNLHNQEEEQQSPKIGSSSVLNNYKLEDSPSRPAAAGDSRKQSDNYEQDL-YYK 574

Query: 776  SRICRLEESIAVMEDRRYSLERK-ADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHD 834
              I  L        + + S +++  D L S   +  K  +     +      + V ++  
Sbjct: 575  DHIQELHNQQEYKSEYQPSPQKEDYDDLESDGFDTLKMNANDQNDQSSHKYGIQVHIEKS 634

Query: 835  RVVEKQLLEIEHEN---KELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAES 891
               E+ + E   EN     ++KK QI+   +  L+  L++++       +K     +   
Sbjct: 635  LAPEQAVDENNLENNLLNPIEKKQQIMSLGDSALKDILNEIKTFKQEKQQKDPEEIVMRL 694

Query: 892  ESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYE 951
             +   + ++++L ++LK ++        Q +K+ E  +I+ + Q ES  +++K  +E  +
Sbjct: 695  STLLQELEVQNLNNSLK-LSQNQIPNDSQIEKDFEQ-KIQASLQKESLKKEEKQNSEAQK 752

Query: 952  KNI-EYVTQLEAQLQEYKNNIENLNMNVEELNKMNLEL----IDKHVQKQQTQ-SPDYTE 1005
              + E+  + +   +E++   E +    EEL ++  +L     D + QKQ+ +      E
Sbjct: 753  DEVTEFNQEDKIDKEEFQKEKEIITKEKEELIQLKEDLRKQKEDFNKQKQEVEKQKSELE 812

Query: 1006 QYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQ 1065
                 +N ++   +++++E+    +++ N        +S    +  Q   KLE +E++ Q
Sbjct: 813  LKAENLNLISMQFEEREKEL----EEVQNTLQQQQEELSQKRKQYEQIQDKLELLEQKEQ 868

Query: 1066 RVSKQ---LLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMS 1122
             V ++   L    +  +E  I V +++ ++ + KE +L       K +   + + I   +
Sbjct: 869  HVKEREETLAQQIEFLKEKDIYVNDREQELLD-KERELESLFEEQKEKEKYLENLINEQN 927

Query: 1123 DDANNVDXXXXXXXXXXXXLK----VQEEEEFIQ--ERSVLQEQSAKL-NTELQECYTKI 1175
                 ++            L     + E+ E ++  E+ ++ EQ+ KL N E +    + 
Sbjct: 928  QKLKLLEQQSINQQSEDLKLLEQQFINEQNEKLKLLEQQLINEQNEKLKNLEEKLVNEQN 987

Query: 1176 IQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVD---QRG 1232
             +L+ L  +L  H    ++ + QL  + +    E D L+S  AE    +   ++   QR 
Sbjct: 988  EKLKLLEQQLDEHQ-AKEKALEQLLKENDGKQKELDLLISQQAEKEQVLQQLMEQQKQRE 1046

Query: 1233 FEIAEL------WKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKI 1286
            +E  ++       +Q L Q  ++  K +H+L  QL A + + EQ LD + +  Q      
Sbjct: 1047 YEFEQIVNEQKQKEQELEQLFSEQSKIKHQLEQQL-AQQIEKEQELDQLINEAQSRNQAT 1105

Query: 1287 VTMEQVTSLQN-KLQDKEEHL----RNLQEKYADVINQIEI---LRSEIEDEKVAFXXXX 1338
             T EQ   L   K ++++E      RN      +  N+ E+   L+ E+ED +       
Sbjct: 1106 FTEEQEIVLTTPKKEERQERTVQEGRNEDFTEGNDENEEELELRLKKEVEDLQQQL-QIS 1164

Query: 1339 XXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDA 1398
                        DL    Q+Y QM E+   N  E   Q KK              R N  
Sbjct: 1165 AQKNQESAKKIIDLEKAVQNY-QMIERDEKNFEEIFRQNKKLEDKIKSYEMEYSARKN-- 1221

Query: 1399 EAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESE 1458
                 +L HQ      +   K H     L Q + + +   +       +IE L YEKE E
Sbjct: 1222 -----QLEHQ-----EQTIAKLHS---QLVQADADLQKYIEDKRLLNDKIEALKYEKEEE 1268

Query: 1459 LAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVS-LNKQVAELNKALEEEVA 1517
              I RLK   +       Q +         E +     ++++ L+ +  +    ++    
Sbjct: 1269 --IKRLKQENDIEKMSRSQSKLMESESIAFESIVGDYKDTINMLSNKCEDYETQIQNLTK 1326

Query: 1518 KTNEMQTALENQEIEIVTLNDEITNLQNMVRASSS---KIQKHVSFASDTKQGRDEQLDN 1574
            + N +  + +  +  + +  +E+ N +  ++  S    ++QK V+      +  ++QL +
Sbjct: 1327 QNNVLVNSFKEIKSNLTSYQEELDNKEEFIQKQSQDMFELQKSVNQYKQMAKKLEDQLKD 1386

Query: 1575 TMNKELLD-AVPRAELDLAMYMLHQRD 1600
              NK   + +  + EL+    +L Q++
Sbjct: 1387 LSNKSQEESSTLQYELEKNNILLEQKN 1413



 Score = 73.7 bits (173), Expect = 4e-11
 Identities = 154/741 (20%), Positives = 330/741 (44%), Gaps = 100/741 (13%)

Query: 152  KEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXX 211
            K+    L   +VK++ +E    DLQE I    QI + K                      
Sbjct: 1751 KQNQQKLKSAEVKLQDLEAKYKDLQESI----QIEQEK----------YSKDIEELQNII 1796

Query: 212  EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271
            E  +Q++  M++N   +    K++  R +KD++ K++ I + +     LE+A  +I    
Sbjct: 1797 ETQQQEINLMEQNMTKL----KNDLDRKVKDLDVKNIEIQAKDSD---LESAYAQIDKID 1849

Query: 272  SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELL 331
             +   +L +              L  + I        E+E+K + ++   +EL K IE  
Sbjct: 1850 IQYQHKLNEYESKQQELANNNNHLEGKLI--------ELEDKYNKDV---SELQKVIE-- 1896

Query: 332  EHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSS 391
                 Q +Q    LE +L   G++++  S+   +   +  +   RN+   +K+   +L S
Sbjct: 1897 -----QQQQDLNNLEQELYNQGSQNEETSNLRVELEKVSIQLDERNSEILIKN--KELDS 1949

Query: 392  ETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQ 451
                 D  ++  + ++ + E+ IQ L K   + +  + E D                IA 
Sbjct: 1950 MYEQIDKIERQYQQKLREQEIKIQDLQKLKKEYDQQLLELDNKNSQD----------IAD 1999

Query: 452  LQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVK---DLIEKLKSA 508
            L+   +Q  E      +    +D+ E  K QE+    L  E++  N++   DLI+K K  
Sbjct: 2000 LKNIIEQQQE-----DLNNMQKDLFENTKHQEE-NNNLRFELERKNIQLNSDLIQKNK-- 2051

Query: 509  EEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFS-KVSDSNKEIVRLTEELHHL 567
              ++ QL+++I+   K   +   + +LKL+ +Q     F  K+ +  ++  +   EL   
Sbjct: 2052 --ELDQLHEQINKIEKQNQQKLRDQELKLQDLQNQKKEFDLKLMEQEEKNNQYITEL--- 2106

Query: 568  SQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIE-MENLAETRLKAISLLESQKFDL 626
             QK+ E ++E  N     +  ++G   E +  +  IE  +N  + +   I+  E +  D+
Sbjct: 2107 -QKIIEQQQEDLNKMEQCLYENNGSQDEINNLRSEIEKQQNELDEKSNEINQKEKELEDM 2165

Query: 627  VQELHILQQKY-DEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENL 685
             Q++  ++++Y D++ +  + + +LQ+    +EI     EE     +    EL  +I+  
Sbjct: 2166 FQQMQEVERQYQDKLNETESKLKELQNQN--NEIIG-KFEESEQKSNFHISELQKIIDQQ 2222

Query: 686  KLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKIS---ELLAKINHE 742
            +    ++   + D    +E+  N L+  ++     T +LE+ +AE +S   EL +K  ++
Sbjct: 2223 QEMIGRMDQDLFDTSRQQEE-NNSLRMELERK---TLQLEQRNAEILSKNKELESK--YD 2276

Query: 743  EQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQL 802
            +  KI+ Q+    K+++ +L  ++++++  + + R+   EE+   +E  +   E +  +L
Sbjct: 2277 QLDKIERQY--QQKLRDFELKQQDLQNQKKELELRLLEQEENGGSLEKLQREFEMQKKEL 2334

Query: 803  GSYLQEKQ-----------KAYSEYTIQEDELVNRL-AVLMDHDRVVEKQLL---EIEHE 847
             + L ++Q           +   +Y  Q  +  NR+ ++ +DH   ++K +    E+  +
Sbjct: 2335 ENILDKQQIEIEELNDKLIRQREDYEYQLAQANNRIQSIELDHKTEIKKLMKLQEELRLQ 2394

Query: 848  NKELQKKNQILLEENQNLQIS 868
            N++++ K + L E+++N+Q S
Sbjct: 2395 NRDMENKYERLKEDHKNIQNS 2415



 Score = 65.7 bits (153), Expect = 1e-08
 Identities = 135/650 (20%), Positives = 264/650 (40%), Gaps = 54/650 (8%)

Query: 148  SNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXX 207
            S  I+E  N +   Q ++ +ME  +  L+  ++ K + ++ KN                 
Sbjct: 1786 SKDIEELQNIIETQQQEINLMEQNMTKLKNDLDRKVKDLDVKN---IEIQAKDSDLESAY 1842

Query: 208  XXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLL-KDIESKDVRISSLEEANKLLEAARFE 266
                +   Q   K+ E + + + E  +    L  K IE +D     + E  K++E  + +
Sbjct: 1843 AQIDKIDIQYQHKLNE-YESKQQELANNNNHLEGKLIELEDKYNKDVSELQKVIEQQQQD 1901

Query: 267  ISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTK 326
            +    + L QEL                L K SI+   E  +EI  K   E+ +M E   
Sbjct: 1902 L----NNLEQELYNQGSQNEETSNLRVELEKVSIQLD-ERNSEILIKNK-ELDSMYEQID 1955

Query: 327  KIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPW 386
            KIE       ++R+   ++++         + +     K S  I+    +N   + +   
Sbjct: 1956 KIE--RQYQQKLREQEIKIQDLQKLKKEYDQQLLELDNKNSQDIA--DLKNIIEQQQEDL 2011

Query: 387  SQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGK- 445
            + +  +       ++ N N   +LE     LN DL+ K   + +              K 
Sbjct: 2012 NNMQKDLFENTKHQEENNNLRFELERKNIQLNSDLIQKNKELDQLHEQINKIEKQNQQKL 2071

Query: 446  -DTLIAQLQLEHQQHMEGPSLI-HVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIE 503
             D  +    L++Q+      L+     N + + E+ K+ EQ +++LN       ++  + 
Sbjct: 2072 RDQELKLQDLQNQKKEFDLKLMEQEEKNNQYITELQKIIEQQQEDLN------KMEQCLY 2125

Query: 504  KLKSAEEQITQLNDEIDAANKNMIKVKSNH-KLKLKQMQKTIDNFSKVSDSNKEIVRLTE 562
            +   ++++I  L  EI+   +N +  KSN    K K+++       +V    ++ +  TE
Sbjct: 2126 ENNGSQDEINNLRSEIE-KQQNELDEKSNEINQKEKELEDMFQQMQEVERQYQDKLNETE 2184

Query: 563  ----ELHHLSQKVA---ELEEEKGNLQL----HLVDYDS---GRMIESDVYKKMIEMENL 608
                EL + + ++    E  E+K N  +     ++D      GRM + D++    + E  
Sbjct: 2185 SKLKELQNQNNEIIGKFEESEQKSNFHISELQKIIDQQQEMIGRM-DQDLFDTSRQQEEN 2243

Query: 609  AETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQI 668
               R++    LE +   L Q    +  K  E+E K   + +++  Q   +++   L++Q 
Sbjct: 2244 NSLRME----LERKTLQLEQRNAEILSKNKELESKYDQLDKIER-QYQQKLRDFELKQQ- 2297

Query: 669  DALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMS 728
              L   KKEL L +   + +   L    ++ E  K+++ N L     E  +L DKL +  
Sbjct: 2298 -DLQNQKKELELRLLEQEENGGSLEKLQREFEMQKKELENILDKQQIEIEELNDKLIR-Q 2355

Query: 729  AEKISELLAKINHEEQS---KIQTQFGIDAKIQERDLYIENIESELSKYK 775
             E     LA+ N+  QS     +T+     K+QE +L ++N + E +KY+
Sbjct: 2356 REDYEYQLAQANNRIQSIELDHKTEIKKLMKLQE-ELRLQNRDME-NKYE 2403


>UniRef50_A2FKU0 Cluster: Viral A-type inclusion protein, putative;
            n=1; Trichomonas vaginalis G3|Rep: Viral A-type inclusion
            protein, putative - Trichomonas vaginalis G3
          Length = 1688

 Score =  170 bits (414), Expect = 2e-40
 Identities = 315/1583 (19%), Positives = 680/1583 (42%), Gaps = 138/1583 (8%)

Query: 55   ERAQKCLENAALVSKRIKEHRKATAELLGRPFVPGISESLANTLKQK-EILMEKIKQYKE 113
            E+ Q+ +  + L+ +R  +  K+  E     +   ++  L N+ K K E   +K+++  E
Sbjct: 8    EQKQELMNESLLLKERFDDDLKSEHEKNKIKYEENLN--LINSQKSKLEEEKDKLEKDLE 65

Query: 114  LSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNALSVLQVKMKIMETTIL 173
              K  +   +                 L ++  L   IK+ D     L  K    +    
Sbjct: 66   KLKEENQKQIDDLQNKISKVENEKKSNLKEIEDLMKQIKDLDQQKIDLSKKFNENQLKNE 125

Query: 174  DLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWK 233
            +  +K+N  DQI   + +                    +  +  M+ +++  I      +
Sbjct: 126  ENIQKLN--DQIENLQKEKENLINEHKNELNNLSISLQDQMESNMSDLEKKLIQANKNHQ 183

Query: 234  DE---KQRLLKDIES----KDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXX 286
            +E   KQ  + D+++    +   IS+L++  + L++   + S    KL  ++ +      
Sbjct: 184  NEMHQKQMEILDLQNLVDKQKGEISNLQKRIQKLDSNNSDNSDMIDKLKSQILELENTNN 243

Query: 287  XXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIA-NMTELTKKIELLEHLNCQIRQTNKEL 345
                     AK + +    + + +EE  + E   N  ++    + ++ L  Q  +  + L
Sbjct: 244  QIEIDLEN-AKSNNDKLNVKISLLEENYNKENELNKNKIENLQKQIKELQDQKAEIEENL 302

Query: 346  ENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKN 405
            EN++  +  +   + +   K    +  K+ R   +++    S++       D ++K  +N
Sbjct: 303  ENQILLLKKKINELEAELMKNKIDLD-KNQRQFDNELGKSHSEIQKMNQKLDENQKKYQN 361

Query: 406  EIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSL 465
            EI KL  +  SL  ++   +  + E              K   +  ++ E Q+H +   +
Sbjct: 362  EIQKLNELNDSLKNEVKKYQNELQEN-------------KKKYVQDMENEMQEHQK--DI 406

Query: 466  IHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKN 525
            I +  + E++ +  +  +  K  L + + D   +++I+ + S    I +   +ID  ++ 
Sbjct: 407  ISLNQSIEEIQKAKENSDAEKHNLENLVNDK--EEIIQNMNST---IKKYQGQIDDLSEK 461

Query: 526  MIKVKSNHKLKLKQMQKT-IDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLH 584
            +  ++ N+K + K ++K  + N   + ++ K+ ++     ++LSQ  +E+ E K N Q  
Sbjct: 462  IKILEENNKYQEKDLEKIKLQNKIDLLENQKQEIQ-----NNLSQTKSEISELKDNNQKL 516

Query: 585  LVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKL 644
            L +  S +M + + Y  M E E LA  + K     +  K +L + L I   K  E  D L
Sbjct: 517  LTN--SQKMTDDNQYL-MKENEKLASEKQKLTEECQKLKENLTK-LQIQLDKIKEDNDNL 572

Query: 645  A-DISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDK 703
              D ++LQ+     + +   L   I  L +  KE  L I N   +K++L   I  L+ +K
Sbjct: 573  ENDNNKLQNKLNEMQNQISDLTSTISKLESDLKEKDL-ISNENKEKDEL---IDMLKREK 628

Query: 704  EDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQ-------SKIQTQFGIDAK 756
            E+ + K + + Q  ++   K +    ++I E+ +K N  ++       S  Q Q    A+
Sbjct: 629  ENQLQKQKEFFQSEIENLQKSKDKEIKEIEEVKSKENERQKINFDETISNFQNQI---AE 685

Query: 757  IQ-ERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAY-S 814
            +Q E+   +EN+    +K   +  +L+  I  +E + ++L  +  ++     E++K +  
Sbjct: 686  LQNEKQKMMENLNQNQAK-NLQTAQLKLDIQKLEGKIFTLNDEKAKIEKQNSEREKRFID 744

Query: 815  EYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQ 874
            EY  Q+ +  N L     H   ++K+  EI    ++L   NQIL  + + L     + + 
Sbjct: 745  EYEAQKRKFDNDL-----HHLYLQKEE-EIASAKRDLN--NQILDLKKEYLNDLAEERKD 796

Query: 875  HYNALVE----KANRTDLAE---SESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIED 927
            H   + E    K    DL E   SE    Q Q+ DL+S + ++  E + L  +  K + D
Sbjct: 797  HQQKIFEHKDEKQKIEDLNEKQKSEILSLQKQIEDLQSQIDKLQKEKEILEKENTKHLVD 856

Query: 928  LEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLE 987
             E   N + E     +K  N+    + +Y  + E +     N+I+N N N  +  +  + 
Sbjct: 857  NE---NLKQEILQNSQKFANDLQNISNDYSKKFEEEF----NDIKNRNKNEIQKLQNQIS 909

Query: 988  LIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYE 1047
            L++   QK Q       ++  ++I  L     +   +I ALN K+N+ Q++   + +D  
Sbjct: 910  LLENEKQKLQNDLNILEKESDSQIKSLQT---ESKSQISALNNKLNDLQINRDGLQAD-N 965

Query: 1048 SKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIP 1107
            S L    + LEN++  ++   K  L++K  N+ L+  +   +    +L ++K+T   N+ 
Sbjct: 966  SNLKNKLSDLENVKSSLES-DKSELENK--NKNLRDFLNNLNASNTDL-QSKIT---NLE 1018

Query: 1108 KTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEE-EFIQERSV-LQEQSAKLN 1165
            K +  + +   +  +D+   +             ++ Q++E + + E+ + L E +   +
Sbjct: 1019 KVKNDLENKMSKLKNDNEKLIQKLAQNQENHEQVVERQKKEIDSLSEKQISLVEDNKNQS 1078

Query: 1166 TELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSIS 1225
              +Q    K+ Q+E  N +L     +N  Q + +  K ++L+ END   S + E  SS+ 
Sbjct: 1079 KNIQNLLEKLSQIENQNQQLQKD--LNDLQNDNISLK-QKLSEENDKSKSILEE-NSSLK 1134

Query: 1226 SAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNK 1285
            + + + G +  E   Q ++++++D Q  ++++   +   E    +  D + S   EE  K
Sbjct: 1135 NEIQEIGKQNTEFQIQ-ISKQKSDLQNQKNDIDKLMLELEHLRTENKD-ISSHMNEE--K 1190

Query: 1286 IVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXX 1345
            +  +E  +   N++ +K++  + L++ +A    Q+EI + + ++    F           
Sbjct: 1191 LKEIEDKSKELNEIFEKQK--KELEKNFA---KQVEIEKLKSDNLSKDFSISQGNLEKEI 1245

Query: 1346 XXXXXDLRTENQSYK---QMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDA---- 1398
                  + +EN+ ++   Q  +++ + +  +N +L                + +D     
Sbjct: 1246 GHLKNVIMSENKRHQAELQNNKKNFIELQNQNQKLISEISSLKDEKFKIQEQKDDQISGL 1305

Query: 1399 EAKVLELTHQLELK------DSEIYQKTHEYTITLTQRNDEFENVR----QQLVEYEKRI 1448
              K+  L ++LE K      + E  QK  E   +L + N++ +  +    +Q++   + +
Sbjct: 1306 HKKLNTLQNELENKSNLLNEEKETIQKLKEIISSLQKENEDLKLQKPIFDEQVMHSNELL 1365

Query: 1449 EDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAEL 1508
            E      ESE+  L  K++   N  + ++KE      +L E +  K      ++ Q+ + 
Sbjct: 1366 EKQKENHESEIGGLLEKINNLENEKQKLEKELYKMEDELDETVQYKKRLEEDISNQMKKH 1425

Query: 1509 NKALEEEVAKTN-EMQTALENQ-EIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQ 1566
             + ++ ++ K + E++  L+ Q EIE+     E   ++N + A     +K+VS  S+ K 
Sbjct: 1426 KQEIDNQMKKNDLEIENLLKKQKEIEL-----ERQEIENKLIAQK---EKYVSELSNLKF 1477

Query: 1567 GRDEQLDNTMNKELLDAVPRAEL 1589
                +  N++N E +    + E+
Sbjct: 1478 DLQNEKSNSLNLEKIKRQNQIEI 1500



 Score =  167 bits (405), Expect = 3e-39
 Identities = 286/1351 (21%), Positives = 582/1351 (43%), Gaps = 123/1351 (9%)

Query: 147  LSNTIKEKDNALSVLQVK-MKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXX 205
            L N +K+  N L   + K ++ ME  + + Q+ I   +Q IE   KA             
Sbjct: 373  LKNEVKKYQNELQENKKKYVQDMENEMQEHQKDIISLNQSIEEIQKAKENSDAEKHNLEN 432

Query: 206  XXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKD---IESKDVRISSLEEANKLLEA 262
                  E+  Q M    + +   + +   EK ++L++    + KD+    L+    LLE 
Sbjct: 433  LVNDK-EEIIQNMNSTIKKYQG-QIDDLSEKIKILEENNKYQEKDLEKIKLQNKIDLLEN 490

Query: 263  ARFEIS-------LEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGS 315
             + EI         E S+L    ++              L K++ E    EK ++ E+  
Sbjct: 491  QKQEIQNNLSQTKSEISELKDNNQKLLTNSQKMTDDNQYLMKEN-EKLASEKQKLTEECQ 549

Query: 316  LEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTE-SKAVSSPSKKGSPLISRKS 374
                N+T+L  +++ ++  N  +   N +L+NKL  M  + S   S+ SK  S L  +  
Sbjct: 550  KLKENLTKLQIQLDKIKEDNDNLENDNNKLQNKLNEMQNQISDLTSTISKLESDLKEKDL 609

Query: 375  GRNTASKMKSPWSQLSSETLNQ-DTDKKINKNEIAKLEMVIQSLNKDLVDKEYVIS-EKD 432
              N   +       L  E  NQ    K+  ++EI  L+   +S +K++ + E V S E +
Sbjct: 610  ISNENKEKDELIDMLKREKENQLQKQKEFFQSEIENLQ---KSKDKEIKEIEEVKSKENE 666

Query: 433  TXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLK-QELND 491
                            IA+LQ E Q+ ME         N      +   Q +L  Q+L  
Sbjct: 667  RQKINFDETISNFQNQIAELQNEKQKMME-------NLNQNQAKNLQTAQLKLDIQKLEG 719

Query: 492  EIKDVN-VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKV 550
            +I  +N  K  IEK  S  E+  +  DE +A      K K ++ L    +QK  +  S  
Sbjct: 720  KIFTLNDEKAKIEKQNSEREK--RFIDEYEAQ-----KRKFDNDLHHLYLQKEEEIASAK 772

Query: 551  SDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDY-DSGRMIESDVYKKMIEMENLA 609
             D N +I+ L +E       + +L EE+ + Q  + ++ D  + IE    K+  E+ +L 
Sbjct: 773  RDLNNQILDLKKEY------LNDLAEERKDHQQKIFEHKDEKQKIEDLNEKQKSEILSLQ 826

Query: 610  ETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQI- 668
                K I  L+SQ   L +E  IL++   E    L D   L+ + + +  K  +  + I 
Sbjct: 827  ----KQIEDLQSQIDKLQKEKEILEK---ENTKHLVDNENLKQEILQNSQKFANDLQNIS 879

Query: 669  -DALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKM 727
             D     ++E   +    K + ++L   I  LEN+K+ + N L    +E+      L+  
Sbjct: 880  NDYSKKFEEEFNDIKNRNKNEIQKLQNQISLLENEKQKLQNDLNILEKESDSQIKSLQTE 939

Query: 728  SAEKISELLAKINHEEQSKIQTQ---FGIDAKIQERDLYIENIESELSKYKSRICRLEES 784
            S  +IS L  K+N  + ++   Q     +  K+ + +    ++ES+ S+ +++   L + 
Sbjct: 940  SKSQISALNNKLNDLQINRDGLQADNSNLKNKLSDLENVKSSLESDKSELENKNKNLRDF 999

Query: 785  IAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMD-HDRVVEKQLLE 843
            +  +      L+ K   L     + +   S+     ++L+ +LA   + H++VVE+Q  E
Sbjct: 1000 LNNLNASNTDLQSKITNLEKVKNDLENKMSKLKNDNEKLIQKLAQNQENHEQVVERQKKE 1059

Query: 844  IEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDL 903
            I+     L +K   L+E+N+N         ++   L+EK ++    E+++ + Q  L DL
Sbjct: 1060 ID----SLSEKQISLVEDNKN-------QSKNIQNLLEKLSQ---IENQNQQLQKDLNDL 1105

Query: 904  ES---NLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQL 960
            ++   +LK+   E       K K I    +E N+ +++ I++    N +++  I   ++ 
Sbjct: 1106 QNDNISLKQKLSEEN----DKSKSI----LEENSSLKNEIQEIGKQNTEFQIQI---SKQ 1154

Query: 961  EAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEI--NKLNALL 1018
            ++ LQ  KN+I+ L + +E L   N + I  H+ +++ +  +   + +NEI   +   L 
Sbjct: 1155 KSDLQNQKNDIDKLMLELEHLRTENKD-ISSHMNEEKLKEIEDKSKELNEIFEKQKKELE 1213

Query: 1019 KQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKL--ENM--EEEMQRVSKQLLDS 1074
            K   +++     K +N    +     + E ++      +  EN   + E+Q   K  ++ 
Sbjct: 1214 KNFAKQVEIEKLKSDNLSKDFSISQGNLEKEIGHLKNVIMSENKRHQAELQNNKKNFIEL 1273

Query: 1075 KQHNEELQILVREQDDQIKELKETK------LTFEMNIPKTEGMIISSTIEPMSDDANNV 1128
            +  N++L   +    D+  +++E K      L  ++N  + E    S+ +    +    +
Sbjct: 1274 QNQNQKLISEISSLKDEKFKIQEQKDDQISGLHKKLNTLQNELENKSNLLNEEKETIQKL 1333

Query: 1129 DXXXXXXXXXXXXLKVQE---EEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTEL 1185
                         LK+Q+   +E+ +    +L++Q     +E+     KI  LE    +L
Sbjct: 1334 KEIISSLQKENEDLKLQKPIFDEQVMHSNELLEKQKENHESEIGGLLEKINNLENEKQKL 1393

Query: 1186 TGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQ 1245
                   ++++++     ++L  +  N +    + +  I + + +   EI  L K+   Q
Sbjct: 1394 EKELYKMEDELDETVQYKKRLEEDISNQMK---KHKQEIDNQMKKNDLEIENLLKK---Q 1447

Query: 1246 READFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEH 1305
            +E + ++   E+  +L A + KY   L +++   Q E +  + +E++   QN+++     
Sbjct: 1448 KEIELER--QEIENKLIAQKEKYVSELSNLKFDLQNEKSNSLNLEKI-KRQNQIE----- 1499

Query: 1306 LRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQ 1365
            +++LQ+K  D+   +  ++ E+++++ +                 +L+      KQ+ E 
Sbjct: 1500 IKSLQDKLNDLQRMLNNIQKELKEKEDSHQNELEKIRERHRNELTNLQ------KQLTEH 1553

Query: 1366 SILNINEEN--AQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEY 1423
             I N+  +N   +LK+              + +D  +++ +L ++LE K +E+ ++  E 
Sbjct: 1554 EIQNLKLQNDMEKLKRKLSENGEKKLDTQSKFDDLSSELEKLRYELEEKQNEVRKRDLEI 1613

Query: 1424 TITLTQRNDEFENVRQQLVEYEKRIEDLTYE 1454
               L  RN+E +  R+++    +R++   Y+
Sbjct: 1614 D-ELNHRNEELQTNREEITHRSQRVKPEFYD 1643



 Score =  153 bits (372), Expect = 3e-35
 Identities = 204/1007 (20%), Positives = 458/1007 (45%), Gaps = 100/1007 (9%)

Query: 632  ILQQKYDEVEDKLADISQLQSDQVCSEIKSVH------LEEQIDALSASKKELALVIENL 685
            +LQ + +E + +L + S L  ++   ++KS H       EE ++ +++ K +L    + L
Sbjct: 1    MLQDEIEEQKQELMNESLLLKERFDDDLKSEHEKNKIKYEENLNLINSQKSKLEEEKDKL 60

Query: 686  KLD----KEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINH 741
            + D    KE+    I DL+N    + N+ ++ ++E  DL  +++ +  +KI +L  K N 
Sbjct: 61   EKDLEKLKEENQKQIDDLQNKISKVENEKKSNLKEIEDLMKQIKDLDQQKI-DLSKKFN- 118

Query: 742  EEQSKIQTQFGIDAKIQERDLYIENIESE----LSKYKSRICRLEESIA-VMEDRRYSLE 796
                  + Q   +  IQ+ +  IEN++ E    ++++K+ +  L  S+   ME     LE
Sbjct: 119  ------ENQLKNEENIQKLNDQIENLQKEKENLINEHKNELNNLSISLQDQMESNMSDLE 172

Query: 797  RKADQLGSYLQEK--QKAYSEYTIQE---------DELVNRLAVL----MDHDRVVEK-- 839
            +K  Q     Q +  QK      +Q            L  R+  L     D+  +++K  
Sbjct: 173  KKLIQANKNHQNEMHQKQMEILDLQNLVDKQKGEISNLQKRIQKLDSNNSDNSDMIDKLK 232

Query: 840  -QLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVE-KANRTDLAESESTKYQ 897
             Q+LE+E+ N +++   +     N  L + +S ++++YN   E   N+ +  + +  + Q
Sbjct: 233  SQILELENTNNQIEIDLENAKSNNDKLNVKISLLEENYNKENELNKNKIENLQKQIKELQ 292

Query: 898  TQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYV 957
             Q  ++E NL     E+Q L+++KK  I +LE E         ++++  + +  K+   +
Sbjct: 293  DQKAEIEENL-----ENQILLLKKK--INELEAELMKNKIDLDKNQRQFDNELGKSHSEI 345

Query: 958  TQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNAL 1017
             ++  +L E +   +N    +++LN++N + +   V+K Q +  +  ++Y+ ++      
Sbjct: 346  QKMNQKLDENQKKYQN---EIQKLNELN-DSLKNEVKKYQNELQENKKKYVQDMEN---E 398

Query: 1018 LKQKDEEIIALNQKINNAQVSYMSMVSD---YESKLAQFTTKLENMEEEMQRVSKQLLDS 1074
            +++  ++II+LNQ I   Q +  +  ++    E+ +      ++NM   +++   Q+ D 
Sbjct: 399  MQEHQKDIISLNQSIEEIQKAKENSDAEKHNLENLVNDKEEIIQNMNSTIKKYQGQIDDL 458

Query: 1075 KQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXX 1134
               +E+++IL      Q K+L++ KL  ++++ + +   I + +     + + +      
Sbjct: 459  ---SEKIKILEENNKYQEKDLEKIKLQNKIDLLENQKQEIQNNLSQTKSEISELKDNNQK 515

Query: 1135 XXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQE 1194
                   +   + +  ++E   L  +  KL  E Q+    + +L+    ++   +   + 
Sbjct: 516  LLTNSQKM-TDDNQYLMKENEKLASEKQKLTEECQKLKENLTKLQIQLDKIKEDNDNLEN 574

Query: 1195 QINQLKSKLEQLNTENDNLLSTVAELRSSI--SSAVDQRGFEIAELWKQHLAQREADFQK 1252
              N+L++KL ++  +  +L ST+++L S +     +     E  EL      ++E   QK
Sbjct: 575  DNNKLQNKLNEMQNQISDLTSTISKLESDLKEKDLISNENKEKDELIDMLKREKENQLQK 634

Query: 1253 TEHELRVQLSAFESKYEQLLDSVQ--SSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQ 1310
             +   + ++   +   ++ +  ++   S + E  KI   E +++ QN++ +    L+N +
Sbjct: 635  QKEFFQSEIENLQKSKDKEIKEIEEVKSKENERQKINFDETISNFQNQIAE----LQNEK 690

Query: 1311 EKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNI 1370
            +K  + +NQ     ++ ++ + A                 D + + +  KQ  E+    I
Sbjct: 691  QKMMENLNQ-----NQAKNLQTAQLKLDIQKLEGKIFTLNDEKAKIE--KQNSEREKRFI 743

Query: 1371 NEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQ-LELKDSEIYQKTHEYTITLTQ 1429
            +E  AQ +K               +  A AK  +L +Q L+LK   +     E       
Sbjct: 744  DEYEAQKRKFDNDLHHLYLQKEEEI--ASAK-RDLNNQILDLKKEYLNDLAEE------- 793

Query: 1430 RNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIE 1489
            R D  + + +   E +K IEDL  +++SE+  L+ ++ +  +  + +QKE EI     +E
Sbjct: 794  RKDHQQKIFEHKDEKQK-IEDLNEKQKSEILSLQKQIEDLQSQIDKLQKEKEI-----LE 847

Query: 1490 ELNVK-ITESVSLNKQVAELNKALEEEVAK-TNEMQTALENQEIEIVTLN-DEITNLQNM 1546
            + N K + ++ +L +++ + ++    ++   +N+     E +  +I   N +EI  LQN 
Sbjct: 848  KENTKHLVDNENLKQEILQNSQKFANDLQNISNDYSKKFEEEFNDIKNRNKNEIQKLQNQ 907

Query: 1547 VRASSSKIQKHVSFASDTKQGRDEQLDN--TMNKELLDAVPRAELDL 1591
            +    ++ QK  +  +  ++  D Q+ +  T +K  + A+     DL
Sbjct: 908  ISLLENEKQKLQNDLNILEKESDSQIKSLQTESKSQISALNNKLNDL 954


>UniRef50_UPI00006CD895 Cluster: hypothetical protein TTHERM_00521980;
            n=1; Tetrahymena thermophila SB210|Rep: hypothetical
            protein TTHERM_00521980 - Tetrahymena thermophila SB210
          Length = 2741

 Score =  170 bits (413), Expect = 3e-40
 Identities = 266/1350 (19%), Positives = 581/1350 (43%), Gaps = 117/1350 (8%)

Query: 251  SSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEI 310
            + L E N+++   + EI     KL ++ +Q                 Q+      E+ ++
Sbjct: 810  NELNERNEVIINMKMEIQSLEQKLQEKEKQIKKIQSEMVEVEEEKIHQAKLVKSLEQFQV 869

Query: 311  EEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLI 370
            ++K   E     E+ +K+  +E +  ++ + N ELE +L         +    +K     
Sbjct: 870  DKKARNE-----EILEKVIEMEKIQKKLNKRNIELEEELKKYKETEINLEVQIEK----- 919

Query: 371  SRKSGRNTASKMKSPWSQLSSETLNQDTDKKIN--KNEIAKLEMVIQSLNKDLVDKEYVI 428
            ++K G      ++        +  NQ +++KI   K +IA L+  I +L  +L       
Sbjct: 920  AKKQGDEKTQDLQKKIKDFEKQ--NQQSNQKIGELKEQIATLQSQISNLQHELQQ----- 972

Query: 429  SEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEG-PSLIHVGTNTEDVNEIAKVQEQLKQ 487
             EKD             +  IAQL+   Q+ ++          N E +    ++Q   +Q
Sbjct: 973  -EKDKNIKQEMDFKKSNENDIAQLEFSLQKQIKNLQQEKEDAVNAERLKYEKEIQAIRRQ 1031

Query: 488  ELNDE-IKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSN---HKLKLK-QMQK 542
            + ++E I +   + L+ +L   ++Q+ QL  ++      + + K      + KL  Q+Q+
Sbjct: 1032 DESEEYISEEKYQKLLSELNIKDQQVKQLQQQLQEQEIALQESKEALYIERQKLDAQLQE 1091

Query: 543  TIDNFS-KVSDSNK-EIVRLTEELHH-LSQKVAELEEEKGNLQLHLVDYDSGRMIESDVY 599
             + N S ++   N+ EI  + ++    L  K A+ E+EK   Q +       + I++  +
Sbjct: 1092 QLKNQSIELKKVNEQEIQNVVDQFEKILKDKAAQFEQEKS--QKNEAFEKELKQIQNR-F 1148

Query: 600  KKMIEMENLAETRLKAISLLESQKF-DLVQELHILQQKYDEVEDKLADISQLQSDQVCSE 658
            K+  E  N    R+  ++ +E     +  +EL  L QK  E+E K A   Q++ +++ SE
Sbjct: 1149 KEHEEEINRENKRVVEVNQMELNGLKENNEELQSLNQKL-EIELKQA---QIRENELQSE 1204

Query: 659  IKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENM 718
             +++  + ++   +AS  E   ++  L+ +K Q+   +   + + E     +    Q+  
Sbjct: 1205 NENLKTKIELIESNASS-ENKTIVNGLQTEKRQIEQNLSQAKRNLELSEKNILELKQKIT 1263

Query: 719  DLTDKLEKMSAEK---ISELLA---KINHEEQSKIQTQFGIDAKIQERDLYIENIESELS 772
             L ++ E +S E+   I +L     +IN  +Q   Q Q  +   IQ++D YI+ +E+E++
Sbjct: 1264 KLEEENESISLERSNLIKQLQGNQDEINDVKQDNQQKQSELAQHIQQKDYYIQELENEIT 1323

Query: 773  KYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRL----- 827
              KS+I +  +   ++      L  K  +L    QEK+K   + + + +E + +L     
Sbjct: 1324 NLKSKIDQSNQETQIITQESIQLNHKISELQQLNQEKEKRIEQISKKAEEAIIQLQKEHQ 1383

Query: 828  ------------AVLMDHDR---VVEKQLLEIEHENKE----LQKKNQILLEENQNLQIS 868
                         +L  +++    +E+Q++ +  +N++     +K+   L  E +  +IS
Sbjct: 1384 QKIEEVIHQSKGEILEGYNKQRAQLEQQIVFLNQQNEQTKQSFEKQIHSLQNEKEQQKIS 1443

Query: 869  LSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDL 928
              + ++    L E+  +    + ES K Q +   LE  +  +  +  +   + + EI+ +
Sbjct: 1444 FENQKEQQRILFEQEKQQLAKQFESQKEQNK-NALEKQINELNEKLNSSKNKYESEIQAI 1502

Query: 929  EIEFNTQIESAIRDKKV-LNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLE 987
              E+N +I+  +   K+ +N+ + + I+ + Q    L    N  +  N  +++  + N  
Sbjct: 1503 NKEYNKKIQDTVEQTKIEMNQTFSQQIKKLEQQLNDLTRQNNEFKQNNNELQKQIQSNQV 1562

Query: 988  LIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYE 1047
              ++ VQ+ +       +Q IN++   N + +   ++I  L ++IN   +   +  +  +
Sbjct: 1563 EAEQKVQQLKQNHQKQLDQSINQVT--NEITESFKQQIATLEKQIN---LLKDTQAASSQ 1617

Query: 1048 SKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIP 1107
            ++ ++FT ++ ++ E++  + ++     QH  +L  L ++    I+E++E     + N  
Sbjct: 1618 NQTSKFTQEINSLSEQIVSLQQENQVLNQHKRDLDSLNQKLQQNIQEIQENLNQSQKNNI 1677

Query: 1108 KTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTE 1167
            K E  I+  + + +      ++            L  +E++  +++ + L+ Q  +L   
Sbjct: 1678 KLES-IVKDSQQKLEQQVKILE-----EEKERYSLIEKEKQSILEKNNQLENQMEELKRN 1731

Query: 1168 LQECYTKIIQLETL--NTELTGHDVVNQEQINQLKSKLEQLNTENDNL------LSTVAE 1219
            LQ+   ++ Q E    N   +     N + + Q  S L Q+N  N+ +      L   + 
Sbjct: 1732 LQQFKVQVQQTEQKQENEAFSKLQNENNDLVQQNNSLLFQINELNNQIHLLEDKLQKSSI 1791

Query: 1220 LRSSISSAVDQRGFEIAEL--WKQHLA--QREADFQKTEHELRVQLSAFESKYEQLLDSV 1275
            L+    +  +Q+G EI +   +   LA  Q   D  + + E + ++ A   K++    S+
Sbjct: 1792 LQGKQITTENQQGEEIFDFEDFADELAASQNAKDKSRQDKEKKSEMVADSGKFKLNFASI 1851

Query: 1276 QSSTQEETNKIV---TMEQVTSLQNK------LQDKEEHLRNLQE--KYADVINQ----- 1319
            Q++   + +++     M+Q   ++NK      + D ++   + QE  K+ D I Q     
Sbjct: 1852 QNNFDNDKDRMQIKRDMQQQQQIKNKEANDYFVDDDDDFDDSNQEKDKFKDQIIQEQGIA 1911

Query: 1320 IEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINE-ENAQLK 1378
            IE  ++EI + K                    L +    YKQ ++Q+ LNINE +N   +
Sbjct: 1912 IEGQKNEISELKNQIDMMFQDINSQREYIQY-LESLVDEYKQKEQQNPLNINEFDNQGGQ 1970

Query: 1379 KSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVR 1438
            +              ++ + ++K+ ++    E  ++EI    ++  I L +     +N  
Sbjct: 1971 QQEHFVEQSDASPNTKILNLKSKLADVQ---ENHETEIL-NLNQQLIALKEEIKGLKNHI 2026

Query: 1439 QQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITES 1498
              L++    +E    EKE+++  L     +N N  +    + +I+  KL  +L  +  + 
Sbjct: 2027 ADLMQANDDLELRIEEKENQILQLHENQQDNVNEEQIGVLQEQIQ--KLQNKLRRQEEDM 2084

Query: 1499 VSLNKQVAELNKALEEEVAKTNEMQTALEN 1528
              L +    LNK ++E + K    Q   E+
Sbjct: 2085 AYLQQVNQNLNKQIDEYMKKLKMKQPGSES 2114



 Score =  160 bits (389), Expect = 3e-37
 Identities = 260/1314 (19%), Positives = 550/1314 (41%), Gaps = 102/1314 (7%)

Query: 316  LEIANMTELTKKIELLEHLNCQIRQTNKELENKL-------ATMGTESKAVSSPSKKGSP 368
            +++ N   + KK ++   L  +++Q N+E +N+L         M  E +++    ++   
Sbjct: 779  IQLQNENHILKKNQIAPELFEKMQQENREAQNELNERNEVIINMKMEIQSLEQKLQEKEK 838

Query: 369  LISR-KSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEI----AKLEMVIQSLNKDLVD 423
             I + +S      + K   ++L         DKK    EI     ++E + + LNK  ++
Sbjct: 839  QIKKIQSEMVEVEEEKIHQAKLVKSLEQFQVDKKARNEEILEKVIEMEKIQKKLNKRNIE 898

Query: 424  -----KEYVISEKDTXXXXXXXXXXGKD-TLIAQLQLEHQQHMEGPSLIHVGTNTEDVNE 477
                 K+Y  +E +           G + T   Q +++  +     S   +G   E +  
Sbjct: 899  LEEELKKYKETEINLEVQIEKAKKQGDEKTQDLQKKIKDFEKQNQQSNQKIGELKEQIAT 958

Query: 478  IAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSN----H 533
            +      L+ EL  E KD N+K  ++  KS E  I QL   +    KN+ + K +     
Sbjct: 959  LQSQISNLQHELQQE-KDKNIKQEMDFKKSNENDIAQLEFSLQKQIKNLQQEKEDAVNAE 1017

Query: 534  KLKLKQMQKTI--DNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSG 591
            +LK ++  + I   + S+   S ++  +L  EL+   Q+V +L+++    ++ L +    
Sbjct: 1018 RLKYEKEIQAIRRQDESEEYISEEKYQKLLSELNIKDQQVKQLQQQLQEQEIALQESKEA 1077

Query: 592  RMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELH-ILQQK---YDEVEDKLADI 647
              IE       ++ E L    ++   + E +  ++V +   IL+ K   +++ + +  + 
Sbjct: 1078 LYIERQKLDAQLQ-EQLKNQSIELKKVNEQEIQNVVDQFEKILKDKAAQFEQEKSQKNEA 1136

Query: 648  SQLQSDQVCSEIKSVHLEEQIDALSASKKEL-ALVIENLKLDKEQLYGTIKDLENDKEDI 706
             + +  Q+ +  K  H EE+I+  +    E+  + +  LK + E+L    + LE + +  
Sbjct: 1137 FEKELKQIQNRFKE-H-EEEINRENKRVVEVNQMELNGLKENNEELQSLNQKLEIELKQA 1194

Query: 707  MNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIEN 766
              +      EN +L  K+E + +   SE    +N  +  K Q    I+  + +    +E 
Sbjct: 1195 QIRENELQSENENLKTKIELIESNASSENKTIVNGLQTEKRQ----IEQNLSQAKRNLEL 1250

Query: 767  IESELSKYKSRICRLEESIAVMEDRRYSLERK--ADQLGSYLQEKQKAYSEYTIQEDELV 824
             E  + + K +I +LEE     E+   SLER     QL     E      +   ++ EL 
Sbjct: 1251 SEKNILELKQKITKLEE-----ENESISLERSNLIKQLQGNQDEINDVKQDNQQKQSELA 1305

Query: 825  NRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKAN 884
              +     + + +E ++  ++ +  +  ++ QI+ +E+  L   +S++QQ  N   EK  
Sbjct: 1306 QHIQQKDYYIQELENEITNLKSKIDQSNQETQIITQESIQLNHKISELQQ-LNQEKEKRI 1364

Query: 885  RTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKK 944
                 ++E    Q Q ++ +  ++ + H       Q K EI +   +   Q+E  I    
Sbjct: 1365 EQISKKAEEAIIQLQ-KEHQQKIEEVIH-------QSKGEILEGYNKQRAQLEQQIVFLN 1416

Query: 945  VLNEKYEKNIE-YVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDY 1003
              NE+ +++ E  +  L+ + ++ K + EN       L +   + + K  + Q+ Q+ + 
Sbjct: 1417 QQNEQTKQSFEKQIHSLQNEKEQQKISFENQKEQQRILFEQEKQQLAKQFESQKEQNKNA 1476

Query: 1004 TEQYINEIN-KLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQ-FTTKLENME 1061
             E+ INE+N KLN+   + + EI A+N++ N         V   + ++ Q F+ +++ +E
Sbjct: 1477 LEKQINELNEKLNSSKNKYESEIQAINKEYNK---KIQDTVEQTKIEMNQTFSQQIKKLE 1533

Query: 1062 EEMQRVSKQLLDSKQHNEELQILVR-EQDDQIKELKETKLTFEMNIPKTEGMIISSTIEP 1120
            +++  +++Q  + KQ+N ELQ  ++  Q +  +++++ K   +  + ++   + +   E 
Sbjct: 1534 QQLNDLTRQNNEFKQNNNELQKQIQSNQVEAEQKVQQLKQNHQKQLDQSINQVTNEITES 1593

Query: 1121 MSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLET 1180
                   ++                +  +F QE + L EQ   L  E Q        L++
Sbjct: 1594 FKQQIATLEKQINLLKDTQAASSQNQTSKFTQEINSLSEQIVSLQQENQVLNQHKRDLDS 1653

Query: 1181 LNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAV-----DQRGFEI 1235
            LN +L       Q+ I +++  L Q    N  L S V + +  +   V     ++  + +
Sbjct: 1654 LNQKL-------QQNIQEIQENLNQSQKNNIKLESIVKDSQQKLEQQVKILEEEKERYSL 1706

Query: 1236 AELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSL 1295
             E  KQ + ++    +    EL+  L  F+ +       VQ + Q++ N     E  + L
Sbjct: 1707 IEKEKQSILEKNNQLENQMEELKRNLQQFKVQ-------VQQTEQKQEN-----EAFSKL 1754

Query: 1296 QNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKV--AFXXXXXXXXXXXXXXXXDLR 1353
            QN+  D  +   +L  +  ++ NQI +L  +++   +                    D  
Sbjct: 1755 QNENNDLVQQNNSLLFQINELNNQIHLLEDKLQKSSILQGKQITTENQQGEEIFDFEDFA 1814

Query: 1354 TENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVL--ELTHQLEL 1411
             E  + +  +++S  +  +++  +  S               ND +   +  ++  Q ++
Sbjct: 1815 DELAASQNAKDKSRQDKEKKSEMVADSGKFKLNFASIQNNFDNDKDRMQIKRDMQQQQQI 1874

Query: 1412 KDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENAN 1471
            K+ E      +        N E +  + Q+++ +    +    + SEL      M ++ N
Sbjct: 1875 KNKEANDYFVDDDDDFDDSNQEKDKFKDQIIQEQGIAIEGQKNEISELKNQIDMMFQDIN 1934

Query: 1472 -HYETMQ-KESEIERVKLIEELN-VKITESVSLNKQVAELNKALEEEVAKTN-------- 1520
               E +Q  ES ++  K  E+ N + I E  +   Q  E    +E+  A  N        
Sbjct: 1935 SQREYIQYLESLVDEYKQKEQQNPLNINEFDNQGGQQQE--HFVEQSDASPNTKILNLKS 1992

Query: 1521 EMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDN 1574
            ++    EN E EI+ LN ++  L+  ++   + I   +  A+D  + R E+ +N
Sbjct: 1993 KLADVQENHETEILNLNQQLIALKEEIKGLKNHIADLMQ-ANDDLELRIEEKEN 2045



 Score =  149 bits (362), Expect = 5e-34
 Identities = 283/1317 (21%), Positives = 578/1317 (43%), Gaps = 146/1317 (11%)

Query: 360  SSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKL--EMVIQSL 417
            + PS+ GS L S  + ++  S     +  + SE L+    + +  +   KL    + Q  
Sbjct: 420  NQPSRNGSQLASPNNFKSQLSISNQNF--MKSERLSPQQQQILPVSPTNKLLNASLGQGF 477

Query: 418  NKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNE 477
            NKD  D EYV+ E+             +  ++AQL +    H +    +++   +++   
Sbjct: 478  NKD--DFEYVLKEQVEYVRKKYLTHFVE--MLAQLGI----HTDN---LNLSNQSDEAPI 526

Query: 478  IAKVQEQLKQELNDEIKDVN-VKDLIEKLKSAEEQITQLNDEIDAANKNMIKV----KSN 532
            I K++E+ ++           V++L +++++ E+++ +   EID     +IKV    +SN
Sbjct: 527  ILKLREEFQKIATKHTGYSQLVQELRQRIETKEKELIEKCSEIDNLKVKVIKVQEEAESN 586

Query: 533  HKL-KLKQMQ-------KTIDNFS----KVSDSNKEIVRLTEELHHLSQKVAELE----E 576
             K+ KL++ Q       K    +S    +V    +EI    EE      K+ +LE    E
Sbjct: 587  PKIDKLEEQQRFRLIQHKFNSKYSFYKFRVQQFKQEIRAKNEEKKQAYSKIQQLEEINLE 646

Query: 577  EKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQK 636
             +   +L+L D D    +  D++  +  ++N+ E     I   E +  D  + L  L+Q 
Sbjct: 647  NERRERLYLEDLD---RLRDDLFMVLDNLKNILE-YFGIIDANEERNVD--RMLDTLRQY 700

Query: 637  YDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENL----KLDKEQL 692
             ++  DK+     +  D    E K +  +E+++ L     E A  I++L    +  K+QL
Sbjct: 701  LEKQADKVFLHKNVFEDM---EKKIIDNQEEVEILKQQNGEFAKQIDDLEEINRTLKDQL 757

Query: 693  -YGTIKDLENDK-----EDIMNKLQN---YIQENMDLTDKLEKMSAEKISELLAKINHEE 743
               ++K+ E DK      D + +LQN    +++N    +  EKM  E   E   ++N   
Sbjct: 758  EIISLKNEEGDKLEQGIRDKIIQLQNENHILKKNQIAPELFEKMQQEN-REAQNELNERN 816

Query: 744  QSKIQTQF---GIDAKIQERDLYIENIESELSK------YKSRICRLEESIAVMEDRR-- 792
            +  I  +     ++ K+QE++  I+ I+SE+ +      +++++ +  E   V +  R  
Sbjct: 817  EVIINMKMEIQSLEQKLQEKEKQIKKIQSEMVEVEEEKIHQAKLVKSLEQFQVDKKARNE 876

Query: 793  ---------YSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDH-DRVVEKQLL 842
                       +++K ++    L+E+ K Y E  I  +  + +     D   + ++K++ 
Sbjct: 877  EILEKVIEMEKIQKKLNKRNIELEEELKKYKETEINLEVQIEKAKKQGDEKTQDLQKKIK 936

Query: 843  EIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQ-TQLR 901
            + E +N++  +K   L E+   LQ  +S++Q       +K  + ++   +S +    QL 
Sbjct: 937  DFEKQNQQSNQKIGELKEQIATLQSQISNLQHELQQEKDKNIKQEMDFKKSNENDIAQLE 996

Query: 902  -DLESNLKRITHEHQTLI--VQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNI--EY 956
              L+  +K +  E +  +   + K E E   I    + E  I ++K      E NI  + 
Sbjct: 997  FSLQKQIKNLQQEKEDAVNAERLKYEKEIQAIRRQDESEEYISEEKYQKLLSELNIKDQQ 1056

Query: 957  VTQLEAQLQEYKNNI-ENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYI-NEINKL 1014
            V QL+ QLQE +  + E+      E  K++ +L  + ++ Q  +     EQ I N +++ 
Sbjct: 1057 VKQLQQQLQEQEIALQESKEALYIERQKLDAQL-QEQLKNQSIELKKVNEQEIQNVVDQF 1115

Query: 1015 NALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLD- 1073
              +LK K  +      + N A          +E +L Q   + +  EEE+ R +K++++ 
Sbjct: 1116 EKILKDKAAQFEQEKSQKNEA----------FEKELKQIQNRFKEHEEEINRENKRVVEV 1165

Query: 1074 -------SKQHNEELQILVREQDDQIK--ELKETKLTFEMNIPKTEGMIISSTIEPMSDD 1124
                    K++NEELQ L ++ + ++K  +++E +L  E    KT+  +I S     S++
Sbjct: 1166 NQMELNGLKENNEELQSLNQKLEIELKQAQIRENELQSENENLKTKIELIESNAS--SEN 1223

Query: 1125 ANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKI-IQLETLNT 1183
               V+            L   +    + E+++L E   K+ T+L+E    I ++   L  
Sbjct: 1224 KTIVNGLQTEKRQIEQNLSQAKRNLELSEKNIL-ELKQKI-TKLEEENESISLERSNLIK 1281

Query: 1184 ELTGH-DVVNQ-EQINQLK-SKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWK 1240
            +L G+ D +N  +Q NQ K S+L Q   + D  +  +    +++ S +DQ   E   + +
Sbjct: 1282 QLQGNQDEINDVKQDNQQKQSELAQHIQQKDYYIQELENEITNLKSKIDQSNQETQIITQ 1341

Query: 1241 Q--HLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQ-- 1296
            +   L  + ++ Q+   E   ++     K E+ +  +Q   Q++  +++   +   L+  
Sbjct: 1342 ESIQLNHKISELQQLNQEKEKRIEQISKKAEEAIIQLQKEHQQKIEEVIHQSKGEILEGY 1401

Query: 1297 NKLQDKEE------HLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXX 1350
            NK + + E      + +N Q K +    QI  L++E E +K++F                
Sbjct: 1402 NKQRAQLEQQIVFLNQQNEQTKQS-FEKQIHSLQNEKEQQKISFENQKEQQRILFEQEKQ 1460

Query: 1351 DLRTENQSYKQMQEQSI-LNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTH-Q 1408
             L  + +S K+  + ++   INE N +L  S               N      +E T  +
Sbjct: 1461 QLAKQFESQKEQNKNALEKQINELNEKLNSSKNKYESEIQAINKEYNKKIQDTVEQTKIE 1520

Query: 1409 LELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILR----L 1464
            +    S+  +K  +    LT++N+EF   +Q   E +K+I+    E E ++  L+     
Sbjct: 1521 MNQTFSQQIKKLEQQLNDLTRQNNEF---KQNNNELQKQIQSNQVEAEQKVQQLKQNHQK 1577

Query: 1465 KMHENANHYETMQKESEIERVKLIE-ELN-VKITESVSLNKQVAELNK---ALEEEVAKT 1519
            ++ ++ N       ES  +++  +E ++N +K T++ S   Q ++  +   +L E++   
Sbjct: 1578 QLDQSINQVTNEITESFKQQIATLEKQINLLKDTQAASSQNQTSKFTQEINSLSEQIVSL 1637

Query: 1520 NEMQTALENQEIEIVTLNDE----ITNLQNMVRASSSKIQKHVSFASDTKQGRDEQL 1572
             +    L   + ++ +LN +    I  +Q  +  S     K  S   D++Q  ++Q+
Sbjct: 1638 QQENQVLNQHKRDLDSLNQKLQQNIQEIQENLNQSQKNNIKLESIVKDSQQKLEQQV 1694



 Score =  139 bits (337), Expect = 5e-31
 Identities = 228/1165 (19%), Positives = 509/1165 (43%), Gaps = 96/1165 (8%)

Query: 473  EDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQ--ITQLNDE--IDAANKNMIK 528
            E++N   + +E+L  E  D ++D ++  +++ LK+  E   I   N+E  +D     + +
Sbjct: 641  EEINLENERRERLYLEDLDRLRD-DLFMVLDNLKNILEYFGIIDANEERNVDRMLDTLRQ 699

Query: 529  VKSNHKLKLKQMQKTIDNFSK-VSDSNKEIVRLTEELHHLSQKVAELEEEKGNL--QLHL 585
                   K+   +   ++  K + D+ +E+  L ++    ++++ +LEE    L  QL +
Sbjct: 700  YLEKQADKVFLHKNVFEDMEKKIIDNQEEVEILKQQNGEFAKQIDDLEEINRTLKDQLEI 759

Query: 586  VDY--DSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDK 643
            +    + G  +E  +  K+I+++N  E  +   + +  + F+ +Q+ +  ++  +E+ ++
Sbjct: 760  ISLKNEEGDKLEQGIRDKIIQLQN--ENHILKKNQIAPELFEKMQQEN--REAQNELNER 815

Query: 644  LADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDK 703
               I  ++ +    E K    E+QI  + +   E    +E  K+ + +L  +++  + DK
Sbjct: 816  NEVIINMKMEIQSLEQKLQEKEKQIKKIQSEMVE----VEEEKIHQAKLVKSLEQFQVDK 871

Query: 704  EDIMNKLQNYIQENMDLTDKLEKMSAEKISELL----AKINHEEQSKIQTQFGIDAKIQE 759
            +    ++   + E   +  KL K + E   EL      +IN E Q +   + G D K Q+
Sbjct: 872  KARNEEILEKVIEMEKIQKKLNKRNIELEEELKKYKETEINLEVQIEKAKKQG-DEKTQD 930

Query: 760  RDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQ 819
                I++ E +  +   +I  L+E IA ++ +  +L+ +  Q      EK K   +    
Sbjct: 931  LQKKIKDFEKQNQQSNQKIGELKEQIATLQSQISNLQHELQQ------EKDKNIKQEMDF 984

Query: 820  EDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHY--- 876
            +    N +A L   +  ++KQ+  ++ E ++     ++  E+     I   D  + Y   
Sbjct: 985  KKSNENDIAQL---EFSLQKQIKNLQQEKEDAVNAERLKYEKEIQA-IRRQDESEEYISE 1040

Query: 877  NALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQI 936
                +  +  ++ + +  + Q QL++ E  L+      + L ++++K    L+ +   Q+
Sbjct: 1041 EKYQKLLSELNIKDQQVKQLQQQLQEQEIALQE---SKEALYIERQK----LDAQLQEQL 1093

Query: 937  ESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQ 996
            ++   + K +NE+  +N+  V Q E  L++     E       E  +  L+ I     K+
Sbjct: 1094 KNQSIELKKVNEQEIQNV--VDQFEKILKDKAAQFEQEKSQKNEAFEKELKQIQNRF-KE 1150

Query: 997  QTQSPDYTEQYINEINKLNAL-LKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTT 1055
              +  +   + + E+N++    LK+ +EE+ +LNQK+           ++ +S+     T
Sbjct: 1151 HEEEINRENKRVVEVNQMELNGLKENNEELQSLNQKLEIELKQAQIRENELQSENENLKT 1210

Query: 1056 KLENMEEEMQRVSKQLL-----DSKQHNEELQILVRE---QDDQIKELKE--TKLTFEMN 1105
            K+E +E      +K ++     + +Q  + L    R     +  I ELK+  TKL  E  
Sbjct: 1211 KIELIESNASSENKTIVNGLQTEKRQIEQNLSQAKRNLELSEKNILELKQKITKLEEENE 1270

Query: 1106 IPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQE-RSVLQEQSAKL 1164
                E   +   ++   D+ N+V               +Q+++ +IQE  + +    +K+
Sbjct: 1271 SISLERSNLIKQLQGNQDEINDVKQDNQQKQSELAQ-HIQQKDYYIQELENEITNLKSKI 1329

Query: 1165 NTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSK-LEQLNTENDN-LLSTVAELRS 1222
            +   QE  T+II  E++      H +   +Q+NQ K K +EQ++ + +  ++    E + 
Sbjct: 1330 DQSNQE--TQIITQESIQLN---HKISELQQLNQEKEKRIEQISKKAEEAIIQLQKEHQQ 1384

Query: 1223 SISSAVDQRGFEIAELWKQHLAQREADF-------QKTEHELRVQLSAFESKYEQLLDSV 1275
             I   + Q   EI E + +  AQ E          ++T+     Q+ + +++ EQ    +
Sbjct: 1385 KIEEVIHQSKGEILEGYNKQRAQLEQQIVFLNQQNEQTKQSFEKQIHSLQNEKEQ--QKI 1442

Query: 1276 QSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQ-IEILRSEIEDEKVAF 1334
                Q+E  +I+  ++   L  + + ++E  +N  EK  + +N+ +   +++ E E  A 
Sbjct: 1443 SFENQKEQQRILFEQEKQQLAKQFESQKEQNKNALEKQINELNEKLNSSKNKYESEIQAI 1502

Query: 1335 XXXXXXXXXXXXXXXX-DL-RTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXX 1392
                             ++ +T +Q  K++ EQ + ++  +N + K+++           
Sbjct: 1503 NKEYNKKIQDTVEQTKIEMNQTFSQQIKKL-EQQLNDLTRQNNEFKQNNNELQKQIQSNQ 1561

Query: 1393 XRVNDAEAKVLEL--THQLELKDSEIYQKTHEYTITLTQRNDEFE---NVRQ--QLVEYE 1445
                +AE KV +L   HQ +L D  I Q T+E T +  Q+    E   N+ +  Q    +
Sbjct: 1562 V---EAEQKVQQLKQNHQKQL-DQSINQVTNEITESFKQQIATLEKQINLLKDTQAASSQ 1617

Query: 1446 KRIEDLTYEKES---ELAILRLK---MHENANHYETMQKESEIERVKLIEELNVKITESV 1499
             +    T E  S   ++  L+ +   ++++    +++ ++ +    ++ E LN     ++
Sbjct: 1618 NQTSKFTQEINSLSEQIVSLQQENQVLNQHKRDLDSLNQKLQQNIQEIQENLNQSQKNNI 1677

Query: 1500 SLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVS 1559
             L   V +  + LE++V    E +      E E  ++ ++   L+N +      +Q+   
Sbjct: 1678 KLESIVKDSQQKLEQQVKILEEEKERYSLIEKEKQSILEKNNQLENQMEELKRNLQQFKV 1737

Query: 1560 FASDTKQGRDEQLDNTMNKELLDAV 1584
                T+Q ++ +  + +  E  D V
Sbjct: 1738 QVQQTEQKQENEAFSKLQNENNDLV 1762



 Score =  128 bits (308), Expect = 2e-27
 Identities = 222/1104 (20%), Positives = 485/1104 (43%), Gaps = 109/1104 (9%)

Query: 546  NFSKVSDSNKEIVRLTEELHHL-------SQKVAELEEEKGNLQLHLVDYDSGRMIESDV 598
            N S  SD    I++L EE   +       SQ V EL +     +  L++  S    E D 
Sbjct: 516  NLSNQSDEAPIILKLREEFQKIATKHTGYSQLVQELRQRIETKEKELIEKCS----EIDN 571

Query: 599  YK-KMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCS 657
             K K+I+++  AE+  K   L E Q+F L+Q  H    KY   + ++    Q        
Sbjct: 572  LKVKVIKVQEEAESNPKIDKLEEQQRFRLIQ--HKFNSKYSFYKFRVQQFKQ-------- 621

Query: 658  EIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNY--IQ 715
            EI++ + EE+  A S  ++   + +EN +  +E+LY  ++DL+  ++D+   L N   I 
Sbjct: 622  EIRAKN-EEKKQAYSKIQQLEEINLENER--RERLY--LEDLDRLRDDLFMVLDNLKNIL 676

Query: 716  ENMDLTDKLEKMSAEKISELLAKINHEEQSKI---QTQF-GIDAKIQERDLYIENIESEL 771
            E   + D  E+ + +++ + L +   ++  K+   +  F  ++ KI +    +E ++ + 
Sbjct: 677  EYFGIIDANEERNVDRMLDTLRQYLEKQADKVFLHKNVFEDMEKKIIDNQEEVEILKQQN 736

Query: 772  SKYKSRICRLEESIAVMEDRRYSLERK---ADQLGSYLQEK--QKAYSEYTIQEDELV-- 824
             ++  +I  LEE    ++D+   +  K    D+L   +++K  Q     + ++++++   
Sbjct: 737  GEFAKQIDDLEEINRTLKDQLEIISLKNEEGDKLEQGIRDKIIQLQNENHILKKNQIAPE 796

Query: 825  --------NRLA--VLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQ 874
                    NR A   L + + V+    +EI+   ++LQ+K +  +++ Q+  + + + + 
Sbjct: 797  LFEKMQQENREAQNELNERNEVIINMKMEIQSLEQKLQEKEK-QIKKIQSEMVEVEEEKI 855

Query: 875  HYNALVEKANRTDL-AESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFN 933
            H   LV+   +  +  ++ + +   ++ ++E   K++ ++    + ++ K+ ++ EI   
Sbjct: 856  HQAKLVKSLEQFQVDKKARNEEILEKVIEMEKIQKKL-NKRNIELEEELKKYKETEINLE 914

Query: 934  TQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKM--NLE-LID 990
             QIE A   KK  +EK +   + +   E Q Q+    I  L   +  L     NL+  + 
Sbjct: 915  VQIEKA---KKQGDEKTQDLQKKIKDFEKQNQQSNQKIGELKEQIATLQSQISNLQHELQ 971

Query: 991  KHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKL 1050
            +   K   Q  D+ +   N+I +L   L+++ + +    +   NA+   +    + ++  
Sbjct: 972  QEKDKNIKQEMDFKKSNENDIAQLEFSLQKQIKNLQQEKEDAVNAE--RLKYEKEIQAIR 1029

Query: 1051 AQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNI-PKT 1109
             Q  ++    EE+ Q++  +L    Q  ++LQ  ++EQ+  ++E KE        +  + 
Sbjct: 1030 RQDESEEYISEEKYQKLLSELNIKDQQVKQLQQQLQEQEIALQESKEALYIERQKLDAQL 1089

Query: 1110 EGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQ 1169
            +  + + +IE    +   +                Q E+E  Q+    +++  ++    +
Sbjct: 1090 QEQLKNQSIELKKVNEQEIQNVVDQFEKILKDKAAQFEQEKSQKNEAFEKELKQIQNRFK 1149

Query: 1170 ECYTKIIQ-----LETLNTELTGHDVVNQEQINQLKSKLE-----------QLNTENDNL 1213
            E   +I +     +E    EL G    N E++  L  KLE           +L +EN+N 
Sbjct: 1150 EHEEEINRENKRVVEVNQMELNGLK-ENNEELQSLNQKLEIELKQAQIRENELQSENEN- 1207

Query: 1214 LSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLD 1273
            L T  EL  S +S+ ++      +  K+ + Q  +  ++        +   + K  +L +
Sbjct: 1208 LKTKIELIESNASSENKTIVNGLQTEKRQIEQNLSQAKRNLELSEKNILELKQKITKLEE 1267

Query: 1274 SVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVA 1333
              +S + E +N I   +Q+   Q+++ D ++  +  Q + A  I Q +    E+E+E   
Sbjct: 1268 ENESISLERSNLI---KQLQGNQDEINDVKQDNQQKQSELAQHIQQKDYYIQELENEITN 1324

Query: 1334 FXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXX 1393
                             +    N    ++Q+     +N+E    K+              
Sbjct: 1325 LKSKIDQSNQETQIITQESIQLNHKISELQQ-----LNQEKE--KRIEQISKKAEEAIIQ 1377

Query: 1394 RVNDAEAKVLELTHQLELKDSEIYQK----THEYTITLTQRNDEF-ENVRQQL--VEYEK 1446
               + + K+ E+ HQ + +  E Y K      +  + L Q+N++  ++  +Q+  ++ EK
Sbjct: 1378 LQKEHQQKIEEVIHQSKGEILEGYNKQRAQLEQQIVFLNQQNEQTKQSFEKQIHSLQNEK 1437

Query: 1447 RIEDLTYE--KESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVS-LNK 1503
              + +++E  KE +  +   +  + A  +E+ +++++    K I ELN K+  S +    
Sbjct: 1438 EQQKISFENQKEQQRILFEQEKQQLAKQFESQKEQNKNALEKQINELNEKLNSSKNKYES 1497

Query: 1504 QVAELNKALEEEVAKTNEMQTALE-----NQEIEIV--TLNDEITNLQNMVRASSSKIQK 1556
            ++  +NK   +++  T E QT +E     +Q+I+ +   LND +T   N  + +++++QK
Sbjct: 1498 EIQAINKEYNKKIQDTVE-QTKIEMNQTFSQQIKKLEQQLND-LTRQNNEFKQNNNELQK 1555

Query: 1557 HVSFASDTKQGRDEQLDNTMNKEL 1580
             +       + + +QL     K+L
Sbjct: 1556 QIQSNQVEAEQKVQQLKQNHQKQL 1579



 Score =  118 bits (284), Expect = 1e-24
 Identities = 266/1506 (17%), Positives = 603/1506 (40%), Gaps = 139/1506 (9%)

Query: 144  VTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXX 203
            V  L    ++ +  LS  +  +++ E  IL+L++KI +    +E +N++ +         
Sbjct: 1227 VNGLQTEKRQIEQNLSQAKRNLELSEKNILELKQKITK----LEEENESISLERSNLIKQ 1282

Query: 204  XXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEK-QRLLKDIESKDVRISSLEEANKLLEA 262
                     D KQ   + Q   +A   + KD   Q L  +I +   +I    +  +++  
Sbjct: 1283 LQGNQDEINDVKQDNQQKQSE-LAQHIQQKDYYIQELENEITNLKSKIDQSNQETQIITQ 1341

Query: 263  ARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEI---EEKGS-LEI 318
               +++ + S+L Q+L Q               A   ++   ++K E    + KG  LE 
Sbjct: 1342 ESIQLNHKISEL-QQLNQEKEKRIEQISKKAEEAIIQLQKEHQQKIEEVIHQSKGEILEG 1400

Query: 319  ANM--TELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGR 376
             N    +L ++I  L   N Q +Q+ ++  + L     + K      K+   ++  +  +
Sbjct: 1401 YNKQRAQLEQQIVFLNQQNEQTKQSFEKQIHSLQNEKEQQKISFENQKEQQRILFEQEKQ 1460

Query: 377  NTASKMKSPWSQLSSETLNQ--DTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTX 434
              A + +S   Q  +    Q  + ++K+N ++  K E  IQ++NK     EY    +DT 
Sbjct: 1461 QLAKQFESQKEQNKNALEKQINELNEKLNSSK-NKYESEIQAINK-----EYNKKIQDTV 1514

Query: 435  XXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIK 494
                        T   Q++   QQ         +   T   NE  +   +L++++     
Sbjct: 1515 EQTKIEM---NQTFSQQIKKLEQQ---------LNDLTRQNNEFKQNNNELQKQIQSN-- 1560

Query: 495  DVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNF--SKVSD 552
             V  +  +++LK   ++  QL+  I+       ++  + K ++  ++K I+    ++ + 
Sbjct: 1561 QVEAEQKVQQLKQNHQK--QLDQSINQVTN---EITESFKQQIATLEKQINLLKDTQAAS 1615

Query: 553  SNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDS-GRMIESDVYKKMIEMENLAET 611
            S  +  + T+E++ LS+++  L++E   L  H  D DS  + ++ ++ +    +    + 
Sbjct: 1616 SQNQTSKFTQEINSLSEQIVSLQQENQVLNQHKRDLDSLNQKLQQNIQEIQENLNQSQKN 1675

Query: 612  RLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDAL 671
             +K  S+++  +  L Q++ IL+++ +         S ++ ++     K+  LE Q++ L
Sbjct: 1676 NIKLESIVKDSQQKLEQQVKILEEEKERY-------SLIEKEKQSILEKNNQLENQMEEL 1728

Query: 672  SASKKELALVIENLKLDKE-QLYGTIKDLENDKEDIMNKLQNYIQENMD----LTDKLEK 726
              + ++  + ++  +  +E + +  +++  ND     N L   I E  +    L DKL+K
Sbjct: 1729 KRNLQQFKVQVQQTEQKQENEAFSKLQNENNDLVQQNNSLLFQINELNNQIHLLEDKLQK 1788

Query: 727  MSAEKISELLAKINHEEQ---------SKIQTQFGIDAKIQERDLYIENIESELSKYKSR 777
             S  +  ++  +    E+             +Q   D   Q+++   E + ++  K+K  
Sbjct: 1789 SSILQGKQITTENQQGEEIFDFEDFADELAASQNAKDKSRQDKEKKSEMV-ADSGKFKLN 1847

Query: 778  ICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDH--DR 835
               ++ +    +DR   ++ K D +    Q K K  ++Y + +D+  +      D   D+
Sbjct: 1848 FASIQNNFDNDKDR---MQIKRD-MQQQQQIKNKEANDYFVDDDDDFDDSNQEKDKFKDQ 1903

Query: 836  VVEKQLLEIEHENKELQK-KNQILL---------EENQNLQISLSDMQQHYNALVEKANR 885
            ++++Q + IE +  E+ + KNQI +         E  Q L+  + + +Q         N 
Sbjct: 1904 IIQEQGIAIEGQKNEISELKNQIDMMFQDINSQREYIQYLESLVDEYKQKEQQNPLNINE 1963

Query: 886  TDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKV 945
             D    +  ++  +  D   N K +  + +   VQ+  E E L +  N Q+ +   + K 
Sbjct: 1964 FDNQGGQQQEHFVEQSDASPNTKILNLKSKLADVQENHETEILNL--NQQLIALKEEIKG 2021

Query: 946  LNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEE-LNKMNLELIDKHVQKQQTQSPDYT 1004
            L       ++    LE +++E +N I  L+ N ++ +N+  + ++ + +QK Q +     
Sbjct: 2022 LKNHIADLMQANDDLELRIEEKENQILQLHENQQDNVNEEQIGVLQEQIQKLQNKLRRQE 2081

Query: 1005 EQ--YINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEE 1062
            E   Y+ ++N+   L KQ DE +  L  K   ++        +YE  L Q   K +  ++
Sbjct: 2082 EDMAYLQQVNQ--NLNKQIDEYMKKLKMKQPGSESGQSKDDEEYEGGLVQQLGKTQQQQQ 2139

Query: 1063 EMQRVSKQLLDSK-QHNEEL-----QILVREQDDQIKELKETKLTFEMNIPKTEGMIISS 1116
            +  +  +Q    K Q  ++L     + + + Q     ++++     + +  +T       
Sbjct: 2140 QQPKQPQQQQSQKAQPQQQLQQQSKKDISQNQIGSYNDMQDQDFENDQDEEETYQSQKPK 2199

Query: 1117 TIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKII 1176
             +     +                  +++ + + IQ    +Q Q  +   E  +   +++
Sbjct: 2200 ILNTQEAEQFQAQLINEKIQLQQQLAELKNDNDAIQTEDQIQIQQIQKRLEHNKKQLQLV 2259

Query: 1177 QLETLNTELTGHDVVN--------QEQINQLKSKLEQLNTENDNLLSTVAELRSSI---S 1225
            Q    N     ++            +Q  +LK + E L  EN N  + +    +S    S
Sbjct: 2260 QEMASNRNKEKYEFAQLKEKHLHLTQQFKELKEETENLKLENQNYRNQLGSKNASPQINS 2319

Query: 1226 SAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNK 1285
               D +   +     + L   +      + +L+     ++   +++   +++ +   +  
Sbjct: 2320 MKPDSKNQSVTST--EQLDMLKLSLMDAQTQLKSMKDKYQKGIKRIKQMIEAPSFSASQP 2377

Query: 1286 IVTMEQVTSLQNKL----QDKEEHLR-NLQEKYADVINQIEILRSEIEDE-------KVA 1333
              T E + +L ++L    Q K + ++  LQ   ++ I+  +  +   ED+       K  
Sbjct: 2378 AETEEDIVALADQLVASHQQKIQQIQLQLQHTLSEGISSHKSPQGNKEDDFVEENEGKTK 2437

Query: 1334 FXXXXXXXXXXXXXXXXDLRTE----NQSYKQMQEQSILNINEEN----AQLKKSSXXXX 1385
                             +L  E    N+   Q  +Q+  ++  E      Q         
Sbjct: 2438 ITDITSLKAYILYSQKLELIIEEALLNKMLAQNDQQNRKDLTSEQYEKVQQYLHILSDFQ 2497

Query: 1386 XXXXXXXXRVNDAEAKVLELTHQ---LELKDSEIYQKTHEYTITLTQRN----DEFENVR 1438
                      ND + K++ L  +   L+  DS   +   +   ++ Q++    ++FEN++
Sbjct: 2498 QSLQEKEKEYNDMQDKLILLAEENEKLKKSDSSSNRNILQKPKSMQQKDPFQINDFENIQ 2557

Query: 1439 QQLVE-YEKRIEDLTYEKESELAILRLKMHENANHYE---TMQKESEIERVKLIEELNVK 1494
            +++      +  + ++   SE  I  L+   N    +   +MQ++S++++ +  E+LN  
Sbjct: 2558 EEIPNPINNQGNESSFLSMSEQIIKELEGANNTKTPQQQVSMQQQSQVQK-QHEEDLNKL 2616

Query: 1495 ITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKI 1554
            + E+  L           +E   +       ++N E+ +  L  EI  L+    A S K 
Sbjct: 2617 MKENSELKASKEYFASRQDELYDELRAKDEIIQNNELYVKNLKKEIRKLKESTEAVSQKE 2676

Query: 1555 QKHVSF 1560
            Q  + F
Sbjct: 2677 QLKIIF 2682



 Score = 98.7 bits (235), Expect = 1e-18
 Identities = 179/903 (19%), Positives = 365/903 (40%), Gaps = 77/903 (8%)

Query: 721  TDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICR 780
            TD L   +    + ++ K+  E Q       G    +QE    IE  E EL +  S I  
Sbjct: 512  TDNLNLSNQSDEAPIILKLREEFQKIATKHTGYSQLVQELRQRIETKEKELIEKCSEIDN 571

Query: 781  LEESIAVMEDRRYSLERKADQLGSY-----LQEK-QKAYSEYTIQEDELVNRLAVLMDHD 834
            L+  +  +++   S   K D+L        +Q K    YS Y  +  +    +    +  
Sbjct: 572  LKVKVIKVQEEAES-NPKIDKLEEQQRFRLIQHKFNSKYSFYKFRVQQFKQEIRAKNEEK 630

Query: 835  RVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESEST 894
            +    ++ ++E  N E +++ ++ LE+   L+  L  +  +   ++E     D  E  + 
Sbjct: 631  KQAYSKIQQLEEINLENERRERLYLEDLDRLRDDLFMVLDNLKNILEYFGIIDANEERNV 690

Query: 895  KYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNI 954
                  R L++ L++   +    +   K   ED+E +     E  +   K  N ++ K I
Sbjct: 691  D-----RMLDT-LRQYLEKQADKVFLHKNVFEDMEKKIIDNQEE-VEILKQQNGEFAKQI 743

Query: 955  EYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEI-NK 1013
            + + ++   L   K+ +E +++  EE +K+   + DK +Q Q         Q   E+  K
Sbjct: 744  DDLEEINRTL---KDQLEIISLKNEEGDKLEQGIRDKIIQLQNENHILKKNQIAPELFEK 800

Query: 1014 LNALLKQKDEEIIALNQKINNAQVSYMSM---VSDYESKLAQFTTKLENMEEE---MQRV 1067
            +    ++   E+   N+ I N ++   S+   + + E ++ +  +++  +EEE     ++
Sbjct: 801  MQQENREAQNELNERNEVIINMKMEIQSLEQKLQEKEKQIKKIQSEMVEVEEEKIHQAKL 860

Query: 1068 SKQL----LDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSD 1123
             K L    +D K  NEE+   V E +   K+L +  +  E  + K +   I+  ++ +  
Sbjct: 861  VKSLEQFQVDKKARNEEILEKVIEMEKIQKKLNKRNIELEEELKKYKETEINLEVQ-IEK 919

Query: 1124 DANNVDXXXXXXXXXXXXLKVQEEE------EFIQERSVLQEQSAKLNTELQECYTKIIQ 1177
                 D             + Q ++      E  ++ + LQ Q + L  ELQ+   K I+
Sbjct: 920  AKKQGDEKTQDLQKKIKDFEKQNQQSNQKIGELKEQIATLQSQISNLQHELQQEKDKNIK 979

Query: 1178 LETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAE 1237
             E    +   +D+   E    L+ +++ L  E ++ ++    L+        +R  E  E
Sbjct: 980  QEMDFKKSNENDIAQLEF--SLQKQIKNLQQEKEDAVNA-ERLKYEKEIQAIRRQDESEE 1036

Query: 1238 LWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDS-VQSSTQEETNKIVTMEQVTSLQ 1296
                     E  +QK   EL ++    +   +QL +  +     +E   I   +    LQ
Sbjct: 1037 YIS------EEKYQKLLSELNIKDQQVKQLQQQLQEQEIALQESKEALYIERQKLDAQLQ 1090

Query: 1297 NKLQDKEEHLRNLQEK-YADVINQIE-ILR---SEIEDEKV----AFXXXXXXXXXXXXX 1347
             +L+++   L+ + E+   +V++Q E IL+   ++ E EK     AF             
Sbjct: 1091 EQLKNQSIELKKVNEQEIQNVVDQFEKILKDKAAQFEQEKSQKNEAFEKELKQIQNRFKE 1150

Query: 1348 XXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTH 1407
               ++  EN+   ++ +  +  + E N +L+  +            R N+ +++   L  
Sbjct: 1151 HEEEINRENKRVVEVNQMELNGLKENNEELQSLNQKLEIELKQAQIRENELQSENENLKT 1210

Query: 1408 QLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMH 1467
            ++EL +S     + E    +     E   + Q L + ++ +E       SE  IL LK  
Sbjct: 1211 KIELIESNA---SSENKTIVNGLQTEKRQIEQNLSQAKRNLE------LSEKNILELK-- 1259

Query: 1468 ENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALE 1527
            +     E   +   +ER  LI++L          N+   E+N   ++   K +E+   ++
Sbjct: 1260 QKITKLEEENESISLERSNLIKQLQG--------NQD--EINDVKQDNQQKQSELAQHIQ 1309

Query: 1528 NQEIEIVTLNDEITNLQNMVRASSSKIQ--KHVSFASDTKQGRDEQLDNTMNKELLDAVP 1585
             ++  I  L +EITNL++ +  S+ + Q     S   + K    +QL+    K +     
Sbjct: 1310 QKDYYIQELENEITNLKSKIDQSNQETQIITQESIQLNHKISELQQLNQEKEKRIEQISK 1369

Query: 1586 RAE 1588
            +AE
Sbjct: 1370 KAE 1372



 Score = 69.7 bits (163), Expect = 6e-10
 Identities = 107/564 (18%), Positives = 247/564 (43%), Gaps = 40/564 (7%)

Query: 474  DVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAAN-KNMIKVKSN 532
            D +E    Q Q  + LN +  +     LI +    ++Q+ +L ++ DA   ++ I+++  
Sbjct: 2186 DQDEEETYQSQKPKILNTQEAEQFQAQLINEKIQLQQQLAELKNDNDAIQTEDQIQIQQI 2245

Query: 533  HKL---KLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYD 589
             K      KQ+Q   +  S  +    E  +L E+  HL+Q+  EL+EE  NL+L   +Y 
Sbjct: 2246 QKRLEHNKKQLQLVQEMASNRNKEKYEFAQLKEKHLHLTQQFKELKEETENLKLENQNYR 2305

Query: 590  S---GRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLAD 646
            +    +     +     + +N + T  + + +L+    D   +L  ++ KY   +  +  
Sbjct: 2306 NQLGSKNASPQINSMKPDSKNQSVTSTEQLDMLKLSLMDAQTQLKSMKDKY---QKGIKR 2362

Query: 647  ISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKD-LENDKED 705
            I Q+      S  +    EE I AL  + + +A   + ++  + QL  T+ + + + K  
Sbjct: 2363 IKQMIEAPSFSASQPAETEEDIVAL--ADQLVASHQQKIQQIQLQLQHTLSEGISSHKSP 2420

Query: 706  IMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIE 765
              NK  ++++EN        K     I+ L A I + ++ ++  +  +  K+  ++    
Sbjct: 2421 QGNKEDDFVEENEG------KTKITDITSLKAYILYSQKLELIIEEALLNKMLAQNDQQN 2474

Query: 766  NIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYT--IQEDEL 823
              +    +Y+    ++++ + ++ D + SL+ K  +    +Q+K    +E    +++ + 
Sbjct: 2475 RKDLTSEQYE----KVQQYLHILSDFQQSLQEKEKEYND-MQDKLILLAEENEKLKKSDS 2529

Query: 824  VNRLAVLMDHDRVVEKQLLEI-EHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEK 882
             +   +L     + +K   +I + EN + +  N I    NQ  + S   M +     +E 
Sbjct: 2530 SSNRNILQKPKSMQQKDPFQINDFENIQEEIPNPI---NNQGNESSFLSMSEQIIKELEG 2586

Query: 883  ANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRD 942
            AN T   + + +  Q      +S +++   E    ++++  E++  +  F ++ +    +
Sbjct: 2587 ANNTKTPQQQVSMQQ------QSQVQKQHEEDLNKLMKENSELKASKEYFASRQDELYDE 2640

Query: 943  KKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPD 1002
             +  +E  + N  YV  L+ ++++ K + E ++   E+L  + ++ I     K++    D
Sbjct: 2641 LRAKDEIIQNNELYVKNLKKEIRKLKESTEAVSQK-EQLKIIFIKFIQAMADKKKQLEAD 2699

Query: 1003 YTEQYINEINKLNALLKQKDEEII 1026
                ++  +  +  +  Q  EEII
Sbjct: 2700 ---NFLAILFSMLGVTDQDKEEII 2720


>UniRef50_A0CKK3 Cluster: Chromosome undetermined scaffold_2, whole
            genome shotgun sequence; n=1; Paramecium tetraurelia|Rep:
            Chromosome undetermined scaffold_2, whole genome shotgun
            sequence - Paramecium tetraurelia
          Length = 2413

 Score =  170 bits (413), Expect = 3e-40
 Identities = 289/1403 (20%), Positives = 595/1403 (42%), Gaps = 120/1403 (8%)

Query: 234  DEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXX 293
            D+ Q ++K ++ +  ++  LEE  + L      ++L   +L  E+E+             
Sbjct: 728  DQNQDIIKLVKQELKKLKKLEEEYQQLRQINSNLTLAQEELNLEIEEKNQLLEQN----- 782

Query: 294  XLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQI---RQTNKELENKLA 350
               KQ +E   +E+ +   K +LE+    +  K +E+ + L  QI   +Q  KE + KL 
Sbjct: 783  ---KQQLEIE-QEQLQNAIKENLELKQQNQTQKLLEVNKQLELQIEGLKQKEKEQQAKLE 838

Query: 351  TMGTESKAVSSPSKKGSPLISRKSGR-NTASKMKSPWSQLSSETLNQDTDKKINKNEIAK 409
            ++ T+++       +   LI + + + N+ S++ S      ++ L Q  +K     E+ K
Sbjct: 839  SLKTQTENQDKKLIQNQNLIQQLNDKENSHSQLNSQLQSDVNDYLKQIQEK---SQEVEK 895

Query: 410  LEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVG 469
             +M + S    +  +E + +E                    Q+Q E QQ+++      + 
Sbjct: 896  FKMDLLSSENRVRQQELIANELKNEIMLLTNENNNHKAQQQQIQ-ELQQNLQ----TQIN 950

Query: 470  TNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKV 529
             N + +  I K++E L Q LN +I          K +  + Q   +N + D     +I  
Sbjct: 951  LNQDQLVSIQKLKEDLNQ-LNQQI--------TYKSEQLDSQSMDINQQKDLLQLQIISQ 1001

Query: 530  KSNHKLKLKQMQKTI-DNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDY 588
            ++    +LKQ+Q+ I +N + +++ +K++   +++L  L   + ++E EKG  +L     
Sbjct: 1002 QN----QLKQLQQQIVENETVITEQSKKLNETSQDLEKLKFDLNQVEIEKG--KLFQQQE 1055

Query: 589  DSGRMIESDVYKKMIEMENLAETRLK-AISLLESQKFDLVQELHILQQKYDEVEDKLADI 647
            DS   I+ D+ +K IE       +LK  I   E +  D + EL I Q++ +E+  K    
Sbjct: 1056 DSLIQIK-DLLQK-IEQGEQHNLKLKDQIEQQEQRLQDNIAELQIKQEEINEMAMK-EQA 1112

Query: 648  SQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIM 707
            S+ + D  C + K +  E QI+     +++L     N      ++   ++DL+ + E++ 
Sbjct: 1113 SKFELD--CLKAKCLSYELQIE----DQEKLISQQNNQAQQLSEIQEQLQDLQKNNEELQ 1166

Query: 708  NKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENI 767
              L N  ++N D+         ++      K N EE+ + + Q   +  IQ RDL I   
Sbjct: 1167 QNL-NDKEQNYDILQNAYYDIGDQ------KKNLEEEIEDKNQ---EISIQNRDLKI--Y 1214

Query: 768  ESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTI-QEDELVNR 826
            + ++ + K+ I +L+E IA   +       +  +L   +Q  +K    Y I  +  L  R
Sbjct: 1215 KEQIDQNKALINQLQEQIAQFRNSANINFAENCKLNEQVQMMKKELESYQIDSKQNLDER 1274

Query: 827  LAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQ---ISLSDMQQHYNALVEKA 883
               + D ++ +     E+E++  ++Q K+  + E N NLQ    +L D++Q       + 
Sbjct: 1275 SDKIKDLEQQIIDLQNELENQQFQIQYKDSKIEELNNNLQETSENLDDIKQELEITSRQL 1334

Query: 884  NRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDK 943
                  + E  K + Q   LE  +++   E Q  I+   ++ E+L    N  IE     +
Sbjct: 1335 KNEQAQKEEELKCKQQ---LEGIIQQQKLEAQQYILTTNQQQENLLSLHNKIIEYCNEIE 1391

Query: 944  KVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDY 1003
             + N+     IE   Q + +++    N+   N  +E+  K NLE  +  +   QTQS + 
Sbjct: 1392 SLKNQISTLQIECEKQ-QKEMEVLNENLNQANTLLED-QKSNLENSEFQINYFQTQSKEI 1449

Query: 1004 TEQY------INEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKL 1057
              QY      + ++ + N +L +         ++I N +      +S  +  LA    + 
Sbjct: 1450 KIQYDQLQEKLQDLEQENEILNRNQSNNAQKQEQIQNEKYILQQEISQLKQSLATLFEER 1509

Query: 1058 ENMEEEMQR----VSKQLLDSKQHNEELQILVREQDD---QIKELKETKLTFEMNIP--- 1107
            +N ++ +Q     +  Q  +  + +++++++  ++ D   ++ EL+E   T++ NI    
Sbjct: 1510 QNNQDRIQELIFTIELQKSEDAKKDQKIELITNQELDLQQRLIELQEQNTTYQQNIESIQ 1569

Query: 1108 ---KTEGMIISSTIEPMSDDANNVD--XXXXXXXXXXXXLKVQEEEEFIQERSV-LQEQS 1161
               K E +I  +  +    D   +D              + ++E+  F+++  +   E S
Sbjct: 1570 NQLKDEQLITENLKQQNEKDQKQIDELKNIEIVQLNQQIVNLKEKIAFLEQNEIQTSELS 1629

Query: 1162 AKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELR 1221
            + L    QE   K  Q E L  E   +D + +E+IN  K+++ QL  +N        +L+
Sbjct: 1630 SHLENLRQEKQIK-EQKEKLFRE--ENDKL-KEEINNFKNQINQLERDNITNEQNYHQLQ 1685

Query: 1222 SSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQE 1281
              + +   +  +E  +  +Q L Q   D  +    L+V  + FE K EQL + ++   +E
Sbjct: 1686 EEMKTI--EIKYEQLKTQEQQLIQLNQDKSEQISNLKVIQTDFEQKLEQLNNEIKVYQEE 1743

Query: 1282 ETNKIVTMEQVTSLQNKLQDKEE----HLRNLQEKYADVINQIEI---LRSEIEDEKVAF 1334
            +  +   + Q+  LQ +L+++ E     L  L E+  D+  Q EI    ++E  D+    
Sbjct: 1744 KQTQENKISQLNELQLQLENQRESITLELEQLNEQIKDLKKQSEINACQQNEKIDQLTNQ 1803

Query: 1335 XXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNIN----------EENAQLKKSSXXX 1384
                            +L  +N+  +  Q Q +  +            EN QL++     
Sbjct: 1804 ITLLQQKNEEQENQIKELSLQNEELQDQQLQFMEQLQTEKQAHNTQLSENYQLQEKLQNE 1863

Query: 1385 XXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEF-ENVRQQLVE 1443
                     +V   E ++ +L   L  KD  + +   +   +   +N++  ++   + ++
Sbjct: 1864 LENAQQSKDQVQRLEQELYQLQQALLDKDESLVRWREQQCCSQYIQNEQIGQSQNTEQID 1923

Query: 1444 YEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNK 1503
             E   E     K      L   + +  N Y+   KE    R+  +E      T+  ++  
Sbjct: 1924 KENNNESEKLNKGIMQESLSNPLEDQDNDYKVEMKEHVNSRIFDLEFDEKSGTQQQNILP 1983

Query: 1504 QVAE-LNKALEEEVAKTNEMQTALENQEIEIVT--LNDEITNL--QNMVRASSSKIQKHV 1558
             V+E +++A +  + ++  +      Q+++     L  +I NL  +N++  S S+ +  +
Sbjct: 1984 AVSENVSEAYDLAIKRSMGLSKDQIIQQLQDQNRLLQQQIENLNQENIIYESPSQHKALI 2043

Query: 1559 -SFASDTKQGRDEQLDNTMNKEL 1580
                   +Q +++QL   +   L
Sbjct: 2044 EELQQQIQQLKNQQLQRIIQSPL 2066



 Score =  168 bits (408), Expect = 1e-39
 Identities = 312/1504 (20%), Positives = 658/1504 (43%), Gaps = 140/1504 (9%)

Query: 152  KEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXX 211
            +E  N    L V++   ++ I  L ++I+++++++   N+                    
Sbjct: 413  QELQNLNDQLNVQIIKQQSQIQLLHKQIDDQNKVMMT-NEKIIQQYQQKEKQLYEELDNQ 471

Query: 212  EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271
            +D ++++ K++ + I++     ++K  LL++IE     I S  +     E    +   + 
Sbjct: 472  KDQQEEINKLKISLISLN----NQKDHLLENIEQLQNEIISKNDVINQAENQINQQVRQL 527

Query: 272  SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTK-KIEL 330
            +K  Q+L +              L ++  +       +I +    +I N  EL K + E 
Sbjct: 528  NKGQQDLIKYENYNEELQQRNKILQERLKKAEDNNLQQILQDKLQDINNKLELLKNENES 587

Query: 331  LEHLNCQIRQTNKE--LENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQ 388
            L H   Q+ Q  K+   E  +  +  +   +   S+     ISR+S +       S  + 
Sbjct: 588  LSH-QIQVLQDEKDKYFEQLIQLIKQKQNNLLYKSQSPKNAISRQSSKFGDQLFISDGNN 646

Query: 389  LSSETLNQDTDK--KINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKD 446
                    + DK  +I     +KL  V Q  N D  +      ++++            +
Sbjct: 647  KQISKFQTELDKFDEIISQITSKLIQVEQQKN-DFRNLNLEQQKQNSQYLLQISNLEQDN 705

Query: 447  TLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLK 506
               +Q+  +  Q M G   +++  N +D+ ++ K + +  ++L +E + +  + +   L 
Sbjct: 706  KKYSQMLQQWHQQMTGNISVNLDQN-QDIIKLVKQELKKLKKLEEEYQQL--RQINSNLT 762

Query: 507  SAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHH 566
             A+E+   LN EI+  N+ + + K   +++ +Q+Q  I    ++   N +  +L E    
Sbjct: 763  LAQEE---LNLEIEEKNQLLEQNKQQLEIEQEQLQNAIKENLELKQQN-QTQKLLEVNKQ 818

Query: 567  LSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAET---RLKAISLLESQ- 622
            L  ++  L++++   Q  L   +S +    +  KK+I+ +NL +    +  + S L SQ 
Sbjct: 819  LELQIEGLKQKEKEQQAKL---ESLKTQTENQDKKLIQNQNLIQQLNDKENSHSQLNSQL 875

Query: 623  KFDLVQELHILQQKYDEVE----DKLADISQL-QSDQVCSEIKS--VHLEEQIDALSASK 675
            + D+   L  +Q+K  EVE    D L+  +++ Q + + +E+K+  + L  + +   A +
Sbjct: 876  QSDVNDYLKQIQEKSQEVEKFKMDLLSSENRVRQQELIANELKNEIMLLTNENNNHKAQQ 935

Query: 676  KELALVIENLK----LDKEQLYGTIK---DLENDKEDIMNKLQNYIQENMDLTDKLEKMS 728
            +++  + +NL+    L+++QL    K   DL    + I  K +    ++MD+  + + + 
Sbjct: 936  QQIQELQQNLQTQINLNQDQLVSIQKLKEDLNQLNQQITYKSEQLDSQSMDINQQKDLLQ 995

Query: 729  AEKISELLAKINHEEQSKIQTQFGI---DAKIQERDLYIENIESELSKYKSRICRL---- 781
             + IS+   ++   +Q  ++ +  I     K+ E    +E ++ +L++ +    +L    
Sbjct: 996  LQIISQQ-NQLKQLQQQIVENETVITEQSKKLNETSQDLEKLKFDLNQVEIEKGKLFQQQ 1054

Query: 782  EESIAVMEDRRYSLE-------RKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHD 834
            E+S+  ++D    +E       +  DQ+    Q  Q   +E  I+++E +N +A + +  
Sbjct: 1055 EDSLIQIKDLLQKIEQGEQHNLKLKDQIEQQEQRLQDNIAELQIKQEE-INEMA-MKEQA 1112

Query: 835  RVVEKQLLEIEHENKELQKKNQILLEENQNLQIS-LSDMQQHYNALVEKANRTDLAESES 893
               E   L+ +  + ELQ ++Q  L   QN Q   LS++Q+    L          +  +
Sbjct: 1113 SKFELDCLKAKCLSYELQIEDQEKLISQQNNQAQQLSEIQEQLQDL----------QKNN 1162

Query: 894  TKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKN 953
             + Q  L D E N   + + +  +  QKK   E++E + N +I    RD K+  E+ ++N
Sbjct: 1163 EELQQNLNDKEQNYDILQNAYYDIGDQKKNLEEEIE-DKNQEISIQNRDLKIYKEQIDQN 1221

Query: 954  IEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINK 1013
               + QL+ Q+ +++N+    N+N  E  K+N     + VQ  + +   Y       +++
Sbjct: 1222 KALINQLQEQIAQFRNSA---NINFAENCKLN-----EQVQMMKKELESYQIDSKQNLDE 1273

Query: 1014 LNALLKQKDEEIIALNQKINNAQ--VSYM-SMVSDYESKLAQFTTKLENMEEEMQRVSKQ 1070
             +  +K  +++II L  ++ N Q  + Y  S + +  + L + +  L+++++E++  S+Q
Sbjct: 1274 RSDKIKDLEQQIIDLQNELENQQFQIQYKDSKIEELNNNLQETSENLDDIKQELEITSRQ 1333

Query: 1071 LLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMI--ISSTIEPMSDDANNV 1128
            L + +   EE ++  ++Q + I  +++ KL  +  I  T      + S    + +  N +
Sbjct: 1334 LKNEQAQKEE-ELKCKQQLEGI--IQQQKLEAQQYILTTNQQQENLLSLHNKIIEYCNEI 1390

Query: 1129 DXXXXXXXXXXXXLKVQEEEEFI------QERSVLQEQSAKL-NTELQECYTKI------ 1175
            +             + Q++E  +      Q  ++L++Q + L N+E Q  Y +       
Sbjct: 1391 ESLKNQISTLQIECEKQQKEMEVLNENLNQANTLLEDQKSNLENSEFQINYFQTQSKEIK 1450

Query: 1176 IQLETLNTELTG----HDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQR 1231
            IQ + L  +L      ++++N+ Q N  + K EQ+  E   L   +++L+ S+++  ++R
Sbjct: 1451 IQYDQLQEKLQDLEQENEILNRNQSNNAQ-KQEQIQNEKYILQQEISQLKQSLATLFEER 1509

Query: 1232 GFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQ 1291
                  +  Q L     + QK+E   + Q    E    Q LD  Q   + +       + 
Sbjct: 1510 QNNQDRI--QELIFT-IELQKSEDAKKDQ--KIELITNQELDLQQRLIELQEQNTTYQQN 1564

Query: 1292 VTSLQNKLQDKEEHLRNLQE------KYADVINQIEI--LRSEIED--EKVAFXXXXXXX 1341
            + S+QN+L+D++    NL++      K  D +  IEI  L  +I +  EK+AF       
Sbjct: 1565 IESIQNQLKDEQLITENLKQQNEKDQKQIDELKNIEIVQLNQQIVNLKEKIAFLEQNEIQ 1624

Query: 1342 XXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAK 1401
                     +LR E    KQ++EQ      EEN +LK+                   E  
Sbjct: 1625 TSELSSHLENLRQE----KQIKEQKEKLFREENDKLKEEINNFKNQINQLERDNITNEQN 1680

Query: 1402 VLELTHQLELKDSEIYQ-KTHEYT-ITLTQ-RNDEFENVRQQLVEYEKRIEDLTYEKESE 1458
              +L  +++  + +  Q KT E   I L Q ++++  N++    ++E+++E L  E    
Sbjct: 1681 YHQLQEEMKTIEIKYEQLKTQEQQLIQLNQDKSEQISNLKVIQTDFEQKLEQLNNE---- 1736

Query: 1459 LAILRLKMHENANHYETMQKESEIERVKL-IEELNVKIT-ESVSLNKQVAELNKALEEEV 1516
                 +K+++     +   K S++  ++L +E     IT E   LN+Q+ +L K  E   
Sbjct: 1737 -----IKVYQEEKQTQE-NKISQLNELQLQLENQRESITLELEQLNEQIKDLKKQSEINA 1790

Query: 1517 AKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQ-KHVSFASDTKQGRDEQLDNT 1575
             + NE    L NQ   +   N+E  N    +   + ++Q + + F    +   ++Q  NT
Sbjct: 1791 CQQNEKIDQLTNQITLLQQKNEEQENQIKELSLQNEELQDQQLQFMEQLQ--TEKQAHNT 1848

Query: 1576 MNKE 1579
               E
Sbjct: 1849 QLSE 1852



 Score =  156 bits (379), Expect = 4e-36
 Identities = 250/1288 (19%), Positives = 554/1288 (43%), Gaps = 122/1288 (9%)

Query: 344  ELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQ--LSSETLNQDTDKK 401
            E++N LA +  E     +P K+ S      + +N   K+ S      L  E LN    + 
Sbjct: 256  EVKNILAFIAREKSRFETPKKQNSQHEQIDNIQNEHQKLVSLHENVMLQIEKLNYQVSQC 315

Query: 402  INKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHME 461
            +  ++  + +  I+ L+++L  KE +                 KD  + QLQ +  ++ +
Sbjct: 316  LQTSQYGQKD-TIKELSQNL--KEMI-----NQFSLSKNTLKDKDQKLIQLQNDLMKYKK 367

Query: 462  GPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDA 521
               L+    N +D++    +Q   + +L     +   + L+ + K  EE   +L +  D 
Sbjct: 368  ---LVE---NKKDIDTQKYIQVINELKLESSNLEKKYQQLVIQEKFGEENNQELQNLNDQ 421

Query: 522  ANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNL 581
             N  +IK +S  +L    + K ID+ +KV  +N++I++         QK  +L EE    
Sbjct: 422  LNVQIIKQQSQIQL----LHKQIDDQNKVMMTNEKIIQ------QYQQKEKQLYEE---- 467

Query: 582  QLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVE 641
                   D+ +  + ++ K  I + +L   +   +  +E  + +++ +  ++ Q  +++ 
Sbjct: 468  ------LDNQKDQQEEINKLKISLISLNNQKDHLLENIEQLQNEIISKNDVINQAENQIN 521

Query: 642  DKLADISQLQSDQVCSEIKSVHLEEQIDALSAS-KKELALVIENLKLDKEQ-LYGTIKDL 699
             ++  +++ Q D +  E  +  L+++   L    KK     ++ +  DK Q +   ++ L
Sbjct: 522  QQVRQLNKGQQDLIKYENYNEELQQRNKILQERLKKAEDNNLQQILQDKLQDINNKLELL 581

Query: 700  ENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQE 759
            +N+ E + +++Q    E     ++L ++  +K + LL K +   ++ I  Q    +K  +
Sbjct: 582  KNENESLSHQIQVLQDEKDKYFEQLIQLIKQKQNNLLYK-SQSPKNAISRQ---SSKFGD 637

Query: 760  RDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQ 819
            +    +    ++SK+++ + + +E I+ +  +   +E++ +   +   E+QK  S+Y +Q
Sbjct: 638  QLFISDGNNKQISKFQTELDKFDEIISQITSKLIQVEQQKNDFRNLNLEQQKQNSQYLLQ 697

Query: 820  EDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNAL 879
               L        + D     Q+L+  H+            +   N+ ++L   Q     +
Sbjct: 698  ISNL--------EQDNKKYSQMLQQWHQ------------QMTGNISVNLDQNQDIIKLV 737

Query: 880  VEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEI-----EDLEIEFNT 934
             ++  +    E E   YQ QLR + SNL  +  E   L +++K ++     + LEIE   
Sbjct: 738  KQELKKLKKLEEE---YQ-QLRQINSNL-TLAQEELNLEIEEKNQLLEQNKQQLEIE-QE 791

Query: 935  QIESAIRDKKVLNE--KYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKH 992
            Q+++AI++   L +  + +K +E   QLE Q++  K   +     +E L K   E  DK 
Sbjct: 792  QLQNAIKENLELKQQNQTQKLLEVNKQLELQIEGLKQKEKEQQAKLESL-KTQTENQDKK 850

Query: 993  VQKQQTQSPDYTEQYINEINKLNALLKQK-DEEIIALNQKINNAQVSYMSMVSDYESKLA 1051
            + + Q       ++  N  ++LN+ L+   ++ +  + +K    +   M ++S  E+++ 
Sbjct: 851  LIQNQNLIQQLNDKE-NSHSQLNSQLQSDVNDYLKQIQEKSQEVEKFKMDLLSS-ENRVR 908

Query: 1052 QFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKE-----TKLTFEMNI 1106
            Q       ++ E+  ++ +  + K   +++Q L +    QI   ++      KL  ++N 
Sbjct: 909  QQELIANELKNEIMLLTNENNNHKAQQQQIQELQQNLQTQINLNQDQLVSIQKLKEDLNQ 968

Query: 1107 PKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLN- 1165
               +    S  ++  S D N                  Q +++ ++  +V+ EQS KLN 
Sbjct: 969  LNQQITYKSEQLDSQSMDINQQKDLLQLQIISQQNQLKQLQQQIVENETVITEQSKKLNE 1028

Query: 1166 --TELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSS 1223
               +L++    + Q+E    +L      +  QI  L  K+EQ    N  L   + +    
Sbjct: 1029 TSQDLEKLKFDLNQVEIEKGKLFQQQEDSLIQIKDLLQKIEQGEQHNLKLKDQIEQQEQR 1088

Query: 1224 ISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEET 1283
            +   + +   +  E+    +A +E   Q ++ EL   L A    YE  ++  +    ++ 
Sbjct: 1089 LQDNIAELQIKQEEI--NEMAMKE---QASKFELDC-LKAKCLSYELQIEDQEKLISQQN 1142

Query: 1284 NKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRS---EIEDEKVAFXXXXXX 1340
            N+    +Q++ +Q +LQD +++   LQ+   D     +IL++   +I D+K         
Sbjct: 1143 NQ---AQQLSEIQEQLQDLQKNNEELQQNLNDKEQNYDILQNAYYDIGDQKKNLEEEIED 1199

Query: 1341 XXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEA 1400
                      DL+     YK+  +Q+   IN+   Q+ +               +N AE 
Sbjct: 1200 KNQEISIQNRDLKI----YKEQIDQNKALINQLQEQIAQ---------FRNSANINFAEN 1246

Query: 1401 KVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYE---KES 1457
              L    Q+  K+ E YQ   +    L +R+D+ +++ QQ+++ +  +E+  ++   K+S
Sbjct: 1247 CKLNEQVQMMKKELESYQIDSKQ--NLDERSDKIKDLEQQIIDLQNELENQQFQIQYKDS 1304

Query: 1458 ELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITE---SVSLNKQVAELNKALEE 1514
            ++  L   + E + + + +++E EI   +L  E   K  E      L   + +     ++
Sbjct: 1305 KIEELNNNLQETSENLDDIKQELEITSRQLKNEQAQKEEELKCKQQLEGIIQQQKLEAQQ 1364

Query: 1515 EVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDN 1574
             +  TN+ Q  L +   +I+   +EI +L+N +     + +K         +  ++   N
Sbjct: 1365 YILTTNQQQENLLSLHNKIIEYCNEIESLKNQISTLQIECEKQQKEMEVLNENLNQA--N 1422

Query: 1575 TMNKELLDAVPRAELDLAMYMLHQRDVR 1602
            T+ ++    +  +E  +  +    ++++
Sbjct: 1423 TLLEDQKSNLENSEFQINYFQTQSKEIK 1450



 Score =  151 bits (365), Expect = 2e-34
 Identities = 279/1424 (19%), Positives = 595/1424 (41%), Gaps = 125/1424 (8%)

Query: 151  IKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKN---KATTXXXXXXXXXXXXX 207
            I  + N L  LQ ++   ET I +  +K+NE  Q +E                       
Sbjct: 998  IISQQNQLKQLQQQIVENETVITEQSKKLNETSQDLEKLKFDLNQVEIEKGKLFQQQEDS 1057

Query: 208  XXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEI 267
                +D  Q++ + +++ + ++ + + ++QRL  +I    ++   + E     +A++FE+
Sbjct: 1058 LIQIKDLLQKIEQGEQHNLKLKDQIEQQEQRLQDNIAELQIKQEEINEMAMKEQASKFEL 1117

Query: 268  SLEHSK-LAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIA-NMTELT 325
                +K L+ EL+                A+Q  E   +E+ +  +K + E+  N+ +  
Sbjct: 1118 DCLKAKCLSYELQ--IEDQEKLISQQNNQAQQLSE--IQEQLQDLQKNNEELQQNLNDKE 1173

Query: 326  KKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSP 385
            +  ++L++    I    K LE ++     E   +S  ++        K  +    + K+ 
Sbjct: 1174 QNYDILQNAYYDIGDQKKNLEEEIEDKNQE---ISIQNR------DLKIYKEQIDQNKAL 1224

Query: 386  WSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGK 445
             +QL  +         IN  E  KL   +Q + K+L  + Y I  K             +
Sbjct: 1225 INQLQEQIAQFRNSANINFAENCKLNEQVQMMKKEL--ESYQIDSKQNLDERSDKIKDLE 1282

Query: 446  DTLI-AQLQLEHQQHME----------GPSLIHVGTNTEDVN-EIAKVQEQLKQELNDEI 493
              +I  Q +LE+QQ               +L     N +D+  E+     QLK E   + 
Sbjct: 1283 QQIIDLQNELENQQFQIQYKDSKIEELNNNLQETSENLDDIKQELEITSRQLKNEQAQKE 1342

Query: 494  KDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDS 553
            +++  K  +E +   ++Q  +    I   N+    + S H   ++   +     +++S  
Sbjct: 1343 EELKCKQQLEGI--IQQQKLEAQQYILTTNQQQENLLSLHNKIIEYCNEIESLKNQISTL 1400

Query: 554  NKEIVRLTEELHHLSQKVAE----LEEEKGNL-----QLHLVDYDSGRM-IESD-VYKKM 602
              E  +  +E+  L++ + +    LE++K NL     Q++     S  + I+ D + +K+
Sbjct: 1401 QIECEKQQKEMEVLNENLNQANTLLEDQKSNLENSEFQINYFQTQSKEIKIQYDQLQEKL 1460

Query: 603  IEMENLAETRLKAISLLESQKFDLVQ-ELHILQQKYDEVEDKLADI---SQLQSDQVCSE 658
             ++E   E  L       +QK + +Q E +ILQQ+  +++  LA +    Q   D++   
Sbjct: 1461 QDLEQENEI-LNRNQSNNAQKQEQIQNEKYILQQEISQLKQSLATLFEERQNNQDRIQEL 1519

Query: 659  IKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENM 718
            I ++ L++  DA    K EL   I N +LD +Q    +++     +  +  +QN +++  
Sbjct: 1520 IFTIELQKSEDAKKDQKIEL---ITNQELDLQQRLIELQEQNTTYQQNIESIQNQLKDEQ 1576

Query: 719  DLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRI 778
             +T+ L++ + EK  + + ++ + E  ++  Q      ++E+  ++E  E + S+  S +
Sbjct: 1577 LITENLKQQN-EKDQKQIDELKNIEIVQLNQQI---VNLKEKIAFLEQNEIQTSELSSHL 1632

Query: 779  CRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVE 838
              L +   + E +      + D+L   +   +   ++  ++ D + N       H    E
Sbjct: 1633 ENLRQEKQIKEQKEKLFREENDKLKEEINNFKNQINQ--LERDNITNEQNY---HQLQEE 1687

Query: 839  KQLLEIEHENKELQKKNQILLEENQNLQIS-LSDMQQHYNALVEKANRTDLAESESTKYQ 897
             + +EI++E  + Q++  I L ++++ QIS L  +Q  +   +E+ N      +E   YQ
Sbjct: 1688 MKTIEIKYEQLKTQEQQLIQLNQDKSEQISNLKVIQTDFEQKLEQLN------NEIKVYQ 1741

Query: 898  TQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIE-FNTQIESAIRDKKV----LNEKYEK 952
             + +  E+ + ++ +E Q L ++ ++E   LE+E  N QI+   +  ++     NEK ++
Sbjct: 1742 EEKQTQENKISQL-NELQ-LQLENQRESITLELEQLNEQIKDLKKQSEINACQQNEKIDQ 1799

Query: 953  NIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEIN 1012
                +T L+ + +E +N I+ L++  EEL    L+ +++   ++Q  +   +E Y  +  
Sbjct: 1800 LTNQITLLQQKNEEQENQIKELSLQNEELQDQQLQFMEQLQTEKQAHNTQLSENYQLQEK 1859

Query: 1013 KLNAL--LKQKDEEIIALNQKINNAQVSYMSM-VSDYESKLAQFTTKLENMEEEMQRVSK 1069
              N L   +Q  +++  L Q++   Q + +    S    +  Q  ++    E+  Q  + 
Sbjct: 1860 LQNELENAQQSKDQVQRLEQELYQLQQALLDKDESLVRWREQQCCSQYIQNEQIGQSQNT 1919

Query: 1070 QLLDSKQHNEELQI---LVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDAN 1126
            + +D + +NE  ++   +++E      E ++     EM       +      E       
Sbjct: 1920 EQIDKENNNESEKLNKGIMQESLSNPLEDQDNDYKVEMKEHVNSRIFDLEFDEKSGTQQQ 1979

Query: 1127 NVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELT 1186
            N+             L ++      +++ + Q Q    N  LQ+      Q+E LN E  
Sbjct: 1980 NILPAVSENVSEAYDLAIKRSMGLSKDQIIQQLQDQ--NRLLQQ------QIENLNQENI 2031

Query: 1187 GHDVVNQEQ--INQLKSKLEQLNTENDNLLSTV-AELRSSISSAVDQRGFEIAELWKQHL 1243
             ++  +Q +  I +L+ +++QL  +N  L   + + L+  I   +D    E+ +  K HL
Sbjct: 2032 IYESPSQHKALIEELQQQIQQL--KNQQLQRIIQSPLQVLIGEHLDDEKDELNQQEKYHL 2089

Query: 1244 AQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKE 1303
               +     T  EL +Q   FESK       +    ++E + ++   Q+  L   ++  +
Sbjct: 2090 LWEKC----TGLELEIQTILFESKETH---KINEQLKKENDSLLL--QINVLNKTVKVWQ 2140

Query: 1304 EHLRNLQEKY-ADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQM 1362
            E   N+ +++    +    +L+  +  E+                    L +E +S  + 
Sbjct: 2141 ETTTNIHQQHDQKQLITFSVLQKVLNQEQ----------QWASQINQIGLSSECESILRQ 2190

Query: 1363 QEQSILNINEENAQLKKSSXXXXXXXXXXXXRVND---AEAKVLELTHQLELKDSEIYQK 1419
              Q++  +     QL                 +N+      +++++T Q E         
Sbjct: 2191 VCQTVYGVPALQKQLDDIKKQSDKEKQEINSLINERCVLSQQIIDITSQHENSSRRNKMS 2250

Query: 1420 THEYTITLTQRNDEFE---NVRQQLVEYEKRIEDLTYEKESELAILRLKMHE-NANHYET 1475
                 + + Q  DE +   N++Q +V+ ++ +E L  E       L++K HE N + Y  
Sbjct: 2251 EPNSALKINQSMDEEDPSLNIKQLIVKLKRELEILKIENHQ--LTLQMKQHEQNEDIYMK 2308

Query: 1476 MQKESEIERVKLIEELNVKITESVSLNKQVAEL-NKALEEEVAK 1518
              K  + E   L E+LN    E   + ++V+   N AL E + K
Sbjct: 2309 QNKLMKDENRSLSEKLNQMSDELQKMAEKVSNSENGALAEHLKK 2352



 Score =  126 bits (304), Expect = 5e-27
 Identities = 231/1225 (18%), Positives = 528/1225 (43%), Gaps = 104/1225 (8%)

Query: 140  QLGDVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXX 199
            Q+ D   L +    +   LS +Q +++ ++    +LQ+ +N+K+Q  +    A       
Sbjct: 1130 QIEDQEKLISQQNNQAQQLSEIQEQLQDLQKNNEELQQNLNDKEQNYDILQNA----YYD 1185

Query: 200  XXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKL 259
                        ED  Q+++ +Q   + +  E  D+ + L+  ++    +I+    +  +
Sbjct: 1186 IGDQKKNLEEEIEDKNQEIS-IQNRDLKIYKEQIDQNKALINQLQE---QIAQFRNSANI 1241

Query: 260  LEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIA 319
              A   +++ +   + +ELE                 K   +   + + E+E +      
Sbjct: 1242 NFAENCKLNEQVQMMKKELESYQIDSKQNLDERSDKIKDLEQQIIDLQNELENQ------ 1295

Query: 320  NMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTA 379
               ++  K   +E LN  +++T++ L++    +   S+ + +   +    +  K      
Sbjct: 1296 -QFQIQYKDSKIEELNNNLQETSENLDDIKQELEITSRQLKNEQAQKEEELKCKQQLEGI 1354

Query: 380  SKMKSPWSQLSSETLNQDTDKKIN-KNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXX 438
             + +   +Q    T NQ  +  ++  N+I +    I+SL K+ +    +  EK       
Sbjct: 1355 IQQQKLEAQQYILTTNQQQENLLSLHNKIIEYCNEIESL-KNQISTLQIECEKQQKEMEV 1413

Query: 439  XXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVN-EIAKVQEQLKQ-ELNDEIKDV 496
                  +   + + Q  + ++ E   + +  T ++++  +  ++QE+L+  E  +EI + 
Sbjct: 1414 LNENLNQANTLLEDQKSNLENSEF-QINYFQTQSKEIKIQYDQLQEKLQDLEQENEILNR 1472

Query: 497  NVKDLIEKLKSAEEQITQLNDEIDAANKN---MIKVKSNHKLKLKQMQKTIDNFSKVSDS 553
            N  +  +K +  + +   L  EI    ++   + + + N++ +++++  TI+   K  D+
Sbjct: 1473 NQSNNAQKQEQIQNEKYILQQEISQLKQSLATLFEERQNNQDRIQELIFTIE-LQKSEDA 1531

Query: 554  NKE--IVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAET 611
             K+  I  +T +   L Q++ EL+E+    Q ++        I++ +  + +  ENL + 
Sbjct: 1532 KKDQKIELITNQELDLQQRLIELQEQNTTYQQNI------ESIQNQLKDEQLITENLKQQ 1585

Query: 612  RLKAISLLESQK-FDLVQELHILQQKYDEVEDKLADISQ--LQSDQVCSEIKSVHLEEQI 668
              K    ++  K  ++VQ    L Q+   +++K+A + Q  +Q+ ++ S ++++  E+QI
Sbjct: 1586 NEKDQKQIDELKNIEIVQ----LNQQIVNLKEKIAFLEQNEIQTSELSSHLENLRQEKQI 1641

Query: 669  DALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNY--IQENMDLTD-KLE 725
                  +KE     EN KL KE++      +   + D +   QNY  +QE M   + K E
Sbjct: 1642 ----KEQKEKLFREENDKL-KEEINNFKNQINQLERDNITNEQNYHQLQEEMKTIEIKYE 1696

Query: 726  KMSAEKISELLAKINHEEQSKIQT----QFGIDAKIQERDLYIENIESELSKYKSRICRL 781
            ++  ++  + L ++N ++  +I      Q   + K+++ +  I+  + E    +++I +L
Sbjct: 1697 QLKTQE--QQLIQLNQDKSEQISNLKVIQTDFEQKLEQLNNEIKVYQEEKQTQENKISQL 1754

Query: 782  EESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQE----DELVNRLAVLMDHDRVV 837
             E    +E++R S+  + +QL   +++ +K       Q+    D+L N++ +L   +   
Sbjct: 1755 NELQLQLENQRESITLELEQLNEQIKDLKKQSEINACQQNEKIDQLTNQITLLQQKNEEQ 1814

Query: 838  EKQLLEIEHENKELQKKNQILLEENQ-NLQISLSDMQQHYNALVEKANRTDLAESESTKY 896
            E Q+ E+  +N+ELQ +    +E+ Q   Q   + + ++Y    +  N  + A+    + 
Sbjct: 1815 ENQIKELSLQNEELQDQQLQFMEQLQTEKQAHNTQLSENYQLQEKLQNELENAQQSKDQV 1874

Query: 897  QTQLRDLESNLKRITHEHQTLIVQKKKE-----IEDLEIEFNTQIESAIRDKKVLNEKYE 951
            Q   ++L    + +  + ++L+  ++++     I++ +I  +   E   ++    +EK  
Sbjct: 1875 QRLEQELYQLQQALLDKDESLVRWREQQCCSQYIQNEQIGQSQNTEQIDKENNNESEKLN 1934

Query: 952  KNI---EYVTQLEAQLQEYKNNI-ENLNMNVEELNKMNLELIDKHVQKQQTQSP----DY 1003
            K I        LE Q  +YK  + E++N  +      +LE  +K   +QQ   P    + 
Sbjct: 1935 KGIMQESLSNPLEDQDNDYKVEMKEHVNSRI-----FDLEFDEKSGTQQQNILPAVSENV 1989

Query: 1004 TEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEE 1063
            +E Y   I +   L K +  + +    ++   Q+  ++  +      +Q    +E ++++
Sbjct: 1990 SEAYDLAIKRSMGLSKDQIIQQLQDQNRLLQQQIENLNQENIIYESPSQHKALIEELQQQ 2049

Query: 1064 MQRVSKQLLDSKQHNEELQILVREQ-DDQIKELKETKLTFEMNIPKTEGMIISSTIEPMS 1122
            +Q++  Q L  +     LQ+L+ E  DD+  EL + +  + +   K  G+ +   I+ + 
Sbjct: 2050 IQQLKNQQL-QRIIQSPLQVLIGEHLDDEKDELNQQE-KYHLLWEKCTGLELE--IQTIL 2105

Query: 1123 DDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLN 1182
             ++                L +Q     +  ++V   Q    N   Q    ++I    L 
Sbjct: 2106 FESKETHKINEQLKKENDSLLLQIN---VLNKTVKVWQETTTNIHQQHDQKQLITFSVL- 2161

Query: 1183 TELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQH 1242
                   V+NQEQ  Q  S++ Q+       LS+  E   SI   V Q  + +  L KQ 
Sbjct: 2162 -----QKVLNQEQ--QWASQINQIG------LSSECE---SILRQVCQTVYGVPALQKQ- 2204

Query: 1243 LAQREADFQKTEHELRVQLSAFESKYEQLLD-SVQSSTQEETNKIVTMEQVTSLQNKLQD 1301
            L   +    K + E+   ++      +Q++D + Q       NK+        + N+  D
Sbjct: 2205 LDDIKKQSDKEKQEINSLINERCVLSQQIIDITSQHENSSRRNKMSEPNSALKI-NQSMD 2263

Query: 1302 KEEHLRNLQEKYADVINQIEILRSE 1326
            +E+   N+++    +  ++EIL+ E
Sbjct: 2264 EEDPSLNIKQLIVKLKRELEILKIE 2288



 Score = 74.9 bits (176), Expect = 2e-11
 Identities = 170/848 (20%), Positives = 335/848 (39%), Gaps = 73/848 (8%)

Query: 756  KIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSE 815
            K + R  Y E  +S    + S +     S    +   Y  + ++D   S L+++    ++
Sbjct: 56   KNRTRANYSEYFDSRKLPFNSTLQPSRSSSCKKKRHFYDEKVESDGKVSQLEDQNMQIND 115

Query: 816  YTIQEDELVNRLAVLMDHDRVVEKQLLEIEHEN-KELQKKNQILLEENQNLQISLSDMQQ 874
            +      + N     +  D  +EK  LEIE  N  +L    Q   EE + +      M+Q
Sbjct: 116  F------IANIPLCKLSKDEQIEK--LEIEKSNLHKLTSGYQKKAEERKTI------MKQ 161

Query: 875  HYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHE-HQTLIVQKKKEIEDLEIEFN 933
             YN L  K    +        Y  Q+   +  L++  HE HQ L    K +   +++E N
Sbjct: 162  LYNILKTKDQEIEYLRKN---YDNQILIQQQKLEQFKHECHQQL---DKADSRIIKLEGN 215

Query: 934  TQIESAIRDKKV--LNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDK 991
             Q     + K++  L  K EK  + +++L  + QE K  I+ +  N+  L  +  E    
Sbjct: 216  LQTALQYKQKRLNDLLVKEEKMRDILSKL-IKKQESKEKIDEVK-NI--LAFIAREKSRF 271

Query: 992  HVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESK-- 1049
               K+Q    +  +   NE  KL +L     E ++   +K+N  QVS     S Y  K  
Sbjct: 272  ETPKKQNSQHEQIDNIQNEHQKLVSL----HENVMLQIEKLNY-QVSQCLQTSQYGQKDT 326

Query: 1050 LAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQ---ILVREQDDQIKELKETKLTFEMNI 1106
            + + +  L+ M  +       L D  Q   +LQ   +  ++  +  K++   K    +N 
Sbjct: 327  IKELSQNLKEMINQFSLSKNTLKDKDQKLIQLQNDLMKYKKLVENKKDIDTQKYIQVINE 386

Query: 1107 PKTEGMIISS-----TIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQS 1161
             K E   +        I+    + NN +            +K Q + + + ++   Q + 
Sbjct: 387  LKLESSNLEKKYQQLVIQEKFGEENNQELQNLNDQLNVQIIKQQSQIQLLHKQIDDQNKV 446

Query: 1162 AKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELR 1221
               N ++ + Y    Q E    E   +    QE+IN+LK  L  LN + D+LL  + +L+
Sbjct: 447  MMTNEKIIQQYQ---QKEKQLYEELDNQKDQQEEINKLKISLISLNNQKDHLLENIEQLQ 503

Query: 1222 SSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQE 1281
            + I S  D     +    +  + Q+     K + +    L  +E+ Y + L       QE
Sbjct: 504  NEIISKND-----VINQAENQINQQVRQLNKGQQD----LIKYEN-YNEELQQRNKILQE 553

Query: 1282 ETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIED--EKVAFXXXXX 1339
               K         LQ+KLQD    L  L+ +   + +QI++L+ E +   E++       
Sbjct: 554  RLKKAEDNNLQQILQDKLQDINNKLELLKNENESLSHQIQVLQDEKDKYFEQLIQLIKQK 613

Query: 1340 XXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAE 1399
                             QS K   +  I + N  N Q+ K              ++    
Sbjct: 614  QNNLLYKSQSPKNAISRQSSKFGDQLFISDGN--NKQISKFQ-TELDKFDEIISQITSKL 670

Query: 1400 AKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIE-DLTYEKESE 1458
             +V +  +     + E  ++  +Y + ++    + +   Q L ++ +++  +++   +  
Sbjct: 671  IQVEQQKNDFRNLNLEQQKQNSQYLLQISNLEQDNKKYSQMLQQWHQQMTGNISVNLDQN 730

Query: 1459 LAILRLKMHENANHYETMQKESEIERVK-----LIEELNVKITESVSL---NKQVAELNK 1510
              I++L   E     +  ++  ++ ++        EELN++I E   L   NKQ  E+ +
Sbjct: 731  QDIIKLVKQELKKLKKLEEEYQQLRQINSNLTLAQEELNLEIEEKNQLLEQNKQQLEIEQ 790

Query: 1511 ALEEEVAKTNEMQTALENQEIEIVTLNDEI-TNLQNMVRASSSKIQKHVSFASDTKQGRD 1569
               +   K N ++   +NQ  +++ +N ++   ++ + +    +  K  S  + T + +D
Sbjct: 791  EQLQNAIKEN-LELKQQNQTQKLLEVNKQLELQIEGLKQKEKEQQAKLESLKTQT-ENQD 848

Query: 1570 EQLDNTMN 1577
            ++L    N
Sbjct: 849  KKLIQNQN 856



 Score = 64.9 bits (151), Expect = 2e-08
 Identities = 159/845 (18%), Positives = 342/845 (40%), Gaps = 70/845 (8%)

Query: 92   ESLANTLKQKEILMEKIKQ-----YKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDV-- 144
            ES+ N LK ++++ E +KQ      K++ +  +  IV+               +  ++  
Sbjct: 1566 ESIQNQLKDEQLITENLKQQNEKDQKQIDELKNIEIVQLNQQIVNLKEKIAFLEQNEIQT 1625

Query: 145  THLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINE-KDQIIEAKNKATTXXXXXXXXX 203
            + LS+ ++       + + K K+       L+E+IN  K+QI + +    T         
Sbjct: 1626 SELSSHLENLRQEKQIKEQKEKLFREENDKLKEEINNFKNQINQLERDNITNEQNYHQLQ 1685

Query: 204  XXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAA 263
                     + K +  K QE  +    + K E+   LK I++ D     LE+ N  ++  
Sbjct: 1686 EEMKTI---EIKYEQLKTQEQQLIQLNQDKSEQISNLKVIQT-DFE-QKLEQLNNEIKVY 1740

Query: 264  RFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTE 323
            + E   + +K++Q L +                +Q  E   + K + E     +   + +
Sbjct: 1741 QEEKQTQENKISQ-LNELQLQLENQRESITLELEQLNEQIKDLKKQSEINACQQNEKIDQ 1799

Query: 324  LTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKK-GSPLISRKSGRNTASKM 382
            LT +I LL+       Q N+E EN++  +  +++ +     +    L + K   NT    
Sbjct: 1800 LTNQITLLQ-------QKNEEQENQIKELSLQNEELQDQQLQFMEQLQTEKQAHNT---Q 1849

Query: 383  KSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVI---SEKDTXXXXXX 439
             S   QL  +  N+  + + +K+++ +LE  +  L + L+DK+  +    E+        
Sbjct: 1850 LSENYQLQEKLQNELENAQQSKDQVQRLEQELYQLQQALLDKDESLVRWREQQCCSQYIQ 1909

Query: 440  XXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVK 499
                G+     Q+  E+    E    ++ G   E ++   + Q+    +   E+K+ +V 
Sbjct: 1910 NEQIGQSQNTEQIDKENNNESE---KLNKGIMQESLSNPLEDQD---NDYKVEMKE-HVN 1962

Query: 500  DLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVR 559
              I  L+  E+  TQ  + + A ++N   V   + L +K+        SK    ++ I +
Sbjct: 1963 SRIFDLEFDEKSGTQQQNILPAVSEN---VSEAYDLAIKRSM----GLSK----DQIIQQ 2011

Query: 560  LTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLL 619
            L ++   L Q++  L +E  N+           + E     + ++ + L       + +L
Sbjct: 2012 LQDQNRLLQQQIENLNQE--NIIYESPSQHKALIEELQQQIQQLKNQQLQRIIQSPLQVL 2069

Query: 620  ESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVH-LEEQIDALSAS-KKE 677
              +  D  ++    Q+KY  + +K   + +L+   +  E K  H + EQ+   + S   +
Sbjct: 2070 IGEHLDDEKDELNQQEKYHLLWEKCTGL-ELEIQTILFESKETHKINEQLKKENDSLLLQ 2128

Query: 678  LALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLA 737
            + ++ + +K+ +E      +  +  +    + LQ  + +      ++ ++      E + 
Sbjct: 2129 INVLNKTVKVWQETTTNIHQQHDQKQLITFSVLQKVLNQEQQWASQINQIGLSSECESIL 2188

Query: 738  KINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRI---CRLEESI--AVMEDRR 792
            +         QT +G+ A  ++ D   +  + E  +  S I   C L + I     +   
Sbjct: 2189 R------QVCQTVYGVPALQKQLDDIKKQSDKEKQEINSLINERCVLSQQIIDITSQHEN 2242

Query: 793  YSLERKADQLGSYLQEKQKAYSE-YTIQEDELVNRLAVLMDHDRVVEKQL-LEI-EHENK 849
             S   K  +  S L+  Q    E  ++   +L+ +L   ++  ++   QL L++ +HE  
Sbjct: 2243 SSRRNKMSEPNSALKINQSMDEEDPSLNIKQLIVKLKRELEILKIENHQLTLQMKQHEQN 2302

Query: 850  E--LQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTD---LAESESTKYQTQLRDLE 904
            E    K+N+++ +EN++L   L+ M      + EK + ++   LAE      Q     L+
Sbjct: 2303 EDIYMKQNKLMKDENRSLSEKLNQMSDELQKMAEKVSNSENGALAEHLKKNIQKFFEALQ 2362

Query: 905  SNLKR 909
               K+
Sbjct: 2363 QEKKQ 2367


>UniRef50_A2FK27 Cluster: Viral A-type inclusion protein, putative;
            n=1; Trichomonas vaginalis G3|Rep: Viral A-type inclusion
            protein, putative - Trichomonas vaginalis G3
          Length = 1677

 Score =  169 bits (412), Expect = 4e-40
 Identities = 254/1193 (21%), Positives = 532/1193 (44%), Gaps = 139/1193 (11%)

Query: 470  TNTEDV-NEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLND----------E 518
            TNT+ + NE+ KV  + KQ L+D++ +       E+L   E QI Q+N            
Sbjct: 43   TNTQILTNELNKVNTE-KQSLHDQLTECK-----ERLALKENQIVQINQLYAQAETDLKN 96

Query: 519  IDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNK-----EIVRLTEELHHLSQKVAE 573
            +  +N  +++  +  ++K+K+    +    K ++ N      ++  L E  H  S+K+ +
Sbjct: 97   LQHSNAELVQAFNEERMKMKKENAELTTQLKKAEKNNMDLSNDLSTLIENTHDESEKIED 156

Query: 574  LEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHIL 633
            L+E+   L+               + K++ E E +     +   LLE++  +L Q+L   
Sbjct: 157  LQEKVKELE--------------TLKKQLEESEKVILEEGEKNQLLENETNNLKQQLSNS 202

Query: 634  QQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDAL-SASKKELALVIENLKLDKEQL 692
            +   D +++ + ++  + ++++ S  K+  L++QI    S S       I  L  +   L
Sbjct: 203  KNNSD-LQNAMDELISM-NEELTS--KNEQLQKQIQEFNSKSSTNDEAAITTLSNENISL 258

Query: 693  YGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFG 752
               I + +   E+++ K+++ IQ  +D   K  +   E  + L +  + E+ S I+    
Sbjct: 259  SNQITERDATIEELLQKIES-IQSELDSKQKELQQLQENNANLQSSNDSEKDSMIEDLIR 317

Query: 753  IDAKIQ-ERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQK 811
               ++Q E  L  E + +    Y+S++  LE  ++ ++    S  ++   L S LQ K+ 
Sbjct: 318  KTDELQKEIGLKSEELSTTKKDYESKLQNLESKLSELQISMDSKTKEVSDLQSQLQLKEN 377

Query: 812  AYSE---YTIQEDELVNRL--AVLMDHDRVVEK--QLLEIEHENKELQK-----KNQI-- 857
            A SE    T Q    + RL   VL +++ + +K  ++ + + E ++LQK     K++I  
Sbjct: 378  AISESSNATTQISSELERLNGIVLRNNELIQQKDTEITKTKQELEDLQKLNDKLKSKINE 437

Query: 858  LLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTL 917
            L E N  L   LS++QQ      EK  ++++   +S   QT +   E    +I  + Q  
Sbjct: 438  LTETNNKLVSDLSELQQMSKETEEKL-KSEIESIQSQLNQTNVMLKEKEGSQIQFDSQIS 496

Query: 918  IVQKK-KEIE---DLEIEFNTQIESAIRDKKVLNEKYEK-NIEYVTQ-LEAQL------- 964
             +QK+  +IE     ++E NT + + + +     E YEK N E   Q LEA L       
Sbjct: 497  EIQKRYNDIEVQLKEKLEANTSLMNQVEELSNKVEYYEKQNFEKRNQELEANLSAITSEY 556

Query: 965  QEYKNNIENLNMNVEE-LNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDE 1023
            Q YK+  E   +++++ L+K N  L  + +QK    S D   +Y NE+N+  AL+    E
Sbjct: 557  QSYKSQSEQKILDIQQKLDKTNNNL--EKLQKDHETSKD---EYHNELNEKEALISSLKE 611

Query: 1024 EIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHN-EELQ 1082
            E  ++NQ++   Q+S     ++ +  ++Q  ++L   EE+ +++ +QL + K    +ELQ
Sbjct: 612  ENSSINQRLQ--QIS-----NENKELMSQINSQLSG-EEKSKQIIEQLTNEKNKQIQELQ 663

Query: 1083 ILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXL 1142
              V   + Q    K+   T  +   K E       +  +S+    +             +
Sbjct: 664  NKVNSLNQQRNNDKQALKTRAVEFFKNEKQQFDQILNIISEKEQKL--GQMSEQMAKKLI 721

Query: 1143 KVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETL--NTELTGHDVVNQEQ--INQ 1198
             V+  +E+  E   L+++   + ++L     K+ +L  +  N + T   ++ +++  I++
Sbjct: 722  LVRRLQEYSIETEKLKDE---VTSQLDIVQQKVKELNQIVENDDATNKQILEEKEQIISE 778

Query: 1199 LKSKLEQLNTEND--------------NLLSTVAELRSSISSAVDQRGFEIAELWKQHLA 1244
            L+ K+E+L + N+              NL + + E+++ IS    +   EI +L  ++  
Sbjct: 779  LEQKIEELESANEELGNSINEKEEDINNLNTKLNEIQNQISQKDSEENNEITKLKDENRT 838

Query: 1245 QREA--DFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTM-----EQVTSLQN 1297
            Q E   + +K +  L++ +S  + + E+ LDS+ + + ++    +       E++ +L  
Sbjct: 839  QLEKINNLEKEKENLQISVSQVKKQLEEQLDSMSAQSNQQVQTYIDQIKSQNEKINNLDR 898

Query: 1298 KLQD---KEEHLRNL----QEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXX 1350
            ++ +   K E L+N     Q+ Y + ++ ++I  S++  EK  F                
Sbjct: 899  EISEYKQKNEELQNSLDGNQKSYEEELSSLKIQLSKLNSEKETFSNEINELKHDIANKDD 958

Query: 1351 DLRTENQSYKQMQEQSIL---NINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTH 1407
             +  + +  ++++ ++++   N+ E   +L +SS              N+    V+E  +
Sbjct: 959  QISLKEKEIQKIENENLVLSQNLTEMKEKLNQSSEELTKLR-------NEYNNSVIEYQN 1011

Query: 1408 QLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMH 1467
            Q+    SE   K  E    + Q   E E + ++    E+    L+   E +L     +M 
Sbjct: 1012 QISALKSEKEGKQMENNENVKQLQSEKEELIKKFTNLEEEKNKLSKSMEKKLQDYAEQMA 1071

Query: 1468 ENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALE 1527
             + +    ++++   + ++ + +  ++  +   +N   +E  K  EEE+ K   +  A  
Sbjct: 1072 ASQDTISLLEQQK--QNLEKVSQEKIQEMKQKCINLVESE-RKKHEEEIEKLKNLVQAKS 1128

Query: 1528 NQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKEL 1580
            +++ +    N  I NLQ+ +  S+  I+ ++S     K      L   +N E+
Sbjct: 1129 DEQTKKSLEN--IQNLQSKLEESNKTIE-NLSSQIKEKDENSLNLQQKLNSEI 1178



 Score =  168 bits (409), Expect = 1e-39
 Identities = 283/1417 (19%), Positives = 616/1417 (43%), Gaps = 131/1417 (9%)

Query: 235  EKQRLLKDI-ESKD---VRISSLEEANKLLEAARFEI-SLEHSKLAQELEQXXXXXXXXX 289
            EKQ L   + E K+   ++ + + + N+L   A  ++ +L+HS    EL Q         
Sbjct: 58   EKQSLHDQLTECKERLALKENQIVQINQLYAQAETDLKNLQHSNA--ELVQAFNEERMKM 115

Query: 290  XXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKL 349
                      ++ + +   ++    S  I N  + ++KIE L+    ++    K+LE   
Sbjct: 116  KKENAELTTQLKKAEKNNMDLSNDLSTLIENTHDESEKIEDLQEKVKELETLKKQLEESE 175

Query: 350  ATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAK 409
              +  E +       + + L  + S     S +++   +L S  +N++     +KNE  +
Sbjct: 176  KVILEEGEKNQLLENETNNLKQQLSNSKNNSDLQNAMDELIS--MNEELT---SKNE--Q 228

Query: 410  LEMVIQSLN-KDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHV 468
            L+  IQ  N K   + E  I+               +D  I +L L+  + ++      +
Sbjct: 229  LQKQIQEFNSKSSTNDEAAITTLSNENISLSNQITERDATIEEL-LQKIESIQS----EL 283

Query: 469  GTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIK 528
             +  +++ ++ +    L Q  ND  KD  ++DLI K    +++I   ++E+    K+   
Sbjct: 284  DSKQKELQQLQENNANL-QSSNDSEKDSMIEDLIRKTDELQKEIGLKSEELSTTKKDYES 342

Query: 529  VKSNHKLKLKQMQKTIDNFSK-VSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQ-LHLV 586
               N + KL ++Q ++D+ +K VSD   ++      +   S    ++  E   L  + L 
Sbjct: 343  KLQNLESKLSELQISMDSKTKEVSDLQSQLQLKENAISESSNATTQISSELERLNGIVLR 402

Query: 587  DYDSGRMIESDVYKKMIEMENLAET--RLKA-ISLLESQKFDLVQELHILQQKYDEVEDK 643
            + +  +  ++++ K   E+E+L +   +LK+ I+ L      LV +L  LQQ   E E+K
Sbjct: 403  NNELIQQKDTEITKTKQELEDLQKLNDKLKSKINELTETNNKLVSDLSELQQMSKETEEK 462

Query: 644  L-ADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLEND 702
            L ++I  +QS    + +     E       +   E+     ++++  ++       L N 
Sbjct: 463  LKSEIESIQSQLNQTNVMLKEKEGSQIQFDSQISEIQKRYNDIEVQLKEKLEANTSLMNQ 522

Query: 703  KEDIMNKLQNYIQENMDLTDK-LEKMSAEKISELLAKINHEEQSKIQTQFGIDA------ 755
             E++ NK++ Y ++N +  ++ LE   +   SE  +  +  EQ  +  Q  +D       
Sbjct: 523  VEELSNKVEYYEKQNFEKRNQELEANLSAITSEYQSYKSQSEQKILDIQQKLDKTNNNLE 582

Query: 756  KIQ-ERDLYIENIESELSKYKSRICRLEESIAVMEDR--RYSLERKA--DQLGSYL--QE 808
            K+Q + +   +   +EL++ ++ I  L+E  + +  R  + S E K    Q+ S L  +E
Sbjct: 583  KLQKDHETSKDEYHNELNEKEALISSLKEENSSINQRLQQISNENKELMSQINSQLSGEE 642

Query: 809  KQKAYSEYTIQE-----DELVNRLAVLMDHDRVVEKQLLE---IEHENKELQKKNQIL-- 858
            K K   E    E      EL N++  L +  R  +KQ L+   +E    E Q+ +QIL  
Sbjct: 643  KSKQIIEQLTNEKNKQIQELQNKVNSL-NQQRNNDKQALKTRAVEFFKNEKQQFDQILNI 701

Query: 859  -LEENQNL---------QISLSDMQQHYNALVEK-----ANRTDLAESESTKYQTQLRDL 903
              E+ Q L         ++ L    Q Y+   EK      ++ D+ + +  +    + + 
Sbjct: 702  ISEKEQKLGQMSEQMAKKLILVRRLQEYSIETEKLKDEVTSQLDIVQQKVKELNQIVEND 761

Query: 904  ESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKK------------VLNEKYE 951
            ++  K+I  E + +I + +++IE+LE   N ++ ++I +K+            + N+  +
Sbjct: 762  DATNKQILEEKEQIISELEQKIEELE-SANEELGNSINEKEEDINNLNTKLNEIQNQISQ 820

Query: 952  KNIEY---VTQLEAQLQ---EYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTE 1005
            K+ E    +T+L+ + +   E  NN+E    N++       + +++ +     QS    +
Sbjct: 821  KDSEENNEITKLKDENRTQLEKINNLEKEKENLQISVSQVKKQLEEQLDSMSAQSNQQVQ 880

Query: 1006 QYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQ 1065
             YI++I   N  +   D EI    QK    Q S       YE +L+    +L  +  E +
Sbjct: 881  TYIDQIKSQNEKINNLDREISEYKQKNEELQNSLDGNQKSYEEELSSLKIQLSKLNSEKE 940

Query: 1066 RVSKQLLDSKQH--NEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSD 1123
              S ++ + K    N++ QI ++E+  +I++++   L    N+ + +  +  S+ E ++ 
Sbjct: 941  TFSNEINELKHDIANKDDQISLKEK--EIQKIENENLVLSQNLTEMKEKLNQSS-EELTK 997

Query: 1124 DANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNT 1183
              N  +            LK ++E + ++      E   +L +E +E   K   LE    
Sbjct: 998  LRNEYNNSVIEYQNQISALKSEKEGKQMEN----NENVKQLQSEKEELIKKFTNLEEEKN 1053

Query: 1184 ELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHL 1243
            +L      ++    +L+   EQ+    D  +S + + + ++     ++   I E+ ++ +
Sbjct: 1054 KL------SKSMEKKLQDYAEQMAASQDT-ISLLEQQKQNLEKVSQEK---IQEMKQKCI 1103

Query: 1244 AQREADFQKTEHELRVQLSAFESKY-EQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDK 1302
               E++ +K E E+    +  ++K  EQ   S+++    ++    + + + +L +++++K
Sbjct: 1104 NLVESERKKHEEEIEKLKNLVQAKSDEQTKKSLENIQNLQSKLEESNKTIENLSSQIKEK 1163

Query: 1303 EEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQM 1362
            +E+  NLQ+K    I  +    SE+ +EK                        N+   ++
Sbjct: 1164 DENSLNLQQKLNSEIQNLNSRISELNEEKTTLSQSLSTCQSENSKL-------NEEILKL 1216

Query: 1363 QEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIY-QKTH 1421
            ++ ++      N+ + K++             +    + +++L  +L+ K +EI  QK  
Sbjct: 1217 KQNNLNYDKTLNSIVSKNNKLLETISLSFENSLVKLNSNIMKLISKLKTKVNEIADQKRA 1276

Query: 1422 EYTI---TLTQRNDEFENV---RQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYET 1475
               I   +++ R +EF+ +   ++++     ++  +  E E  L  L +K+ +    YE+
Sbjct: 1277 VMEIMANSVSAREEEFDKIADKKEEIRNESIKLNQMKEENEKTLQELNIKLRD----YES 1332

Query: 1476 MQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTN--EMQTALENQEIEI 1533
            ++++ E     L+  LN K +E     K+++E  K  +E++ + +  E +  +  + IE+
Sbjct: 1333 IKRDYE----SLMSSLNAKKSEIEQKEKELSEKEKINDEKLTELSVAEKKALMLQRTIEM 1388

Query: 1534 VTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDE 1570
                 ++   +N+ RA +   ++   FA +  Q R E
Sbjct: 1389 DRTQYDMEG-ENIRRAKNELEKRRHQFALEVAQHRIE 1424



 Score =  168 bits (409), Expect = 1e-39
 Identities = 301/1489 (20%), Positives = 624/1489 (41%), Gaps = 126/1489 (8%)

Query: 147  LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXX 206
            LSN I E+D  +  L  K++ +++   +L  K  E  Q+ E      +            
Sbjct: 258  LSNQITERDATIEELLQKIESIQS---ELDSKQKELQQLQENNANLQSSNDSEKDSMIED 314

Query: 207  XXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRL---LKDIE----SKDVRISSLEEANKL 259
                 ++ ++++    E     + +++ + Q L   L +++    SK   +S L+   +L
Sbjct: 315  LIRKTDELQKEIGLKSEELSTTKKDYESKLQNLESKLSELQISMDSKTKEVSDLQSQLQL 374

Query: 260  LEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQ--SIEPSCEEKTEIEEKGSLE 317
             E A  E S   ++++ ELE+                 +    +   E+  ++ +K   +
Sbjct: 375  KENAISESSNATTQISSELERLNGIVLRNNELIQQKDTEITKTKQELEDLQKLNDKLKSK 434

Query: 318  IANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRN 377
            I  +TE   K  L+  L+ +++Q +KE E KL +   E +++ S   + + ++  K G  
Sbjct: 435  INELTETNNK--LVSDLS-ELQQMSKETEEKLKS---EIESIQSQLNQTNVMLKEKEG-- 486

Query: 378  TASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDK-EYVISEKDTXXX 436
              S+++   SQ+S E   +  D ++   E  +    + +  ++L +K EY   EK     
Sbjct: 487  --SQIQFD-SQIS-EIQKRYNDIEVQLKEKLEANTSLMNQVEELSNKVEYY--EKQNFEK 540

Query: 437  XXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNE-IAKVQEQLKQELNDEIKD 495
                       + ++ Q    Q  +   ++ +    +  N  + K+Q+  +   ++   +
Sbjct: 541  RNQELEANLSAITSEYQSYKSQSEQ--KILDIQQKLDKTNNNLEKLQKDHETSKDEYHNE 598

Query: 496  VNVKD-LIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSN 554
            +N K+ LI  LK     I Q   +I   NK ++  + N +L  ++  K I      ++ N
Sbjct: 599  LNEKEALISSLKEENSSINQRLQQISNENKELMS-QINSQLSGEEKSKQIIE-QLTNEKN 656

Query: 555  KEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLK 614
            K+I  L  +++ L+Q   +   +K  L+   V++      E   + +++ + +  E +L 
Sbjct: 657  KQIQELQNKVNSLNQ---QRNNDKQALKTRAVEFFKN---EKQQFDQILNIISEKEQKLG 710

Query: 615  AISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVH-LEEQIDALSA 673
             +S   ++K  LV+ L    Q+Y    +KL D    Q D V  ++K ++ + E  DA + 
Sbjct: 711  QMSEQMAKKLILVRRL----QEYSIETEKLKDEVTSQLDIVQQKVKELNQIVENDDATNK 766

Query: 674  SK--------KELALVIENLKLDKEQLYGTIKDLENDKEDI---MNKLQNYI-QENMDLT 721
                       EL   IE L+   E+L  +I + E D  ++   +N++QN I Q++ +  
Sbjct: 767  QILEEKEQIISELEQKIEELESANEELGNSINEKEEDINNLNTKLNEIQNQISQKDSEEN 826

Query: 722  DKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSK----YKSR 777
            +++ K+  E  ++L  KIN+ E+ K   Q  +    ++ +  ++++ ++ ++    Y  +
Sbjct: 827  NEITKLKDENRTQL-EKINNLEKEKENLQISVSQVKKQLEEQLDSMSAQSNQQVQTYIDQ 885

Query: 778  ICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVV 837
            I    E I  ++      ++K ++L + L   QK+Y E   +   L  +L+ L       
Sbjct: 886  IKSQNEKINNLDREISEYKQKNEELQNSLDGNQKSYEE---ELSSLKIQLSKLNSEKETF 942

Query: 838  EKQLLEIEHE--NKELQ---KKNQILLEENQNLQIS--LSDMQQHYNALVEKANRTDLAE 890
              ++ E++H+  NK+ Q   K+ +I   EN+NL +S  L++M++  N   E+  +     
Sbjct: 943  SNEINELKHDIANKDDQISLKEKEIQKIENENLVLSQNLTEMKEKLNQSSEELTKLRNEY 1002

Query: 891  SEST-KYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEK 949
            + S  +YQ Q+  L+S  +    E+   + Q + E E+L  +F T +E    +K  L++ 
Sbjct: 1003 NNSVIEYQNQISALKSEKEGKQMENNENVKQLQSEKEELIKKF-TNLEE---EKNKLSKS 1058

Query: 950  YEKNIE-YVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYI 1008
             EK ++ Y  Q+ A     ++ I  L    + L K++ E I +  QK         +++ 
Sbjct: 1059 MEKKLQDYAEQMAAS----QDTISLLEQQKQNLEKVSQEKIQEMKQKCINLVESERKKHE 1114

Query: 1009 NEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVS 1068
             EI KL  L++ K +E     + + N Q        + +SKL +    +EN+  +++   
Sbjct: 1115 EEIEKLKNLVQAKSDE--QTKKSLENIQ--------NLQSKLEESNKTIENLSSQIKEKD 1164

Query: 1069 KQLLDSKQH-NEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANN 1127
            +  L+ +Q  N E+Q L    + +I EL E K T   ++   +        E +    NN
Sbjct: 1165 ENSLNLQQKLNSEIQNL----NSRISELNEEKTTLSQSLSTCQSENSKLNEEILKLKQNN 1220

Query: 1128 VDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQS--AKLNTELQECYTKIIQLETLNTEL 1185
            ++             K+ E      E S+++  S   KL ++L+    +I   +    E+
Sbjct: 1221 LNYDKTLNSIVSKNNKLLETISLSFENSLVKLNSNIMKLISKLKTKVNEIADQKRAVMEI 1280

Query: 1186 TGHDV-VNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSA-VDQRGFEIAELWKQHL 1243
              + V   +E+ +++  K E++  E+  L     E   ++    +  R +E  +      
Sbjct: 1281 MANSVSAREEEFDKIADKKEEIRNESIKLNQMKEENEKTLQELNIKLRDYESIK------ 1334

Query: 1244 AQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKE 1303
                 D++     L  + S  E K ++L +  + + ++ T   V  ++   LQ  ++   
Sbjct: 1335 ----RDYESLMSSLNAKKSEIEQKEKELSEKEKINDEKLTELSVAEKKALMLQRTIEMDR 1390

Query: 1304 EHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQ-SYKQM 1362
                   E      N++E  R +   E                    D+   N+ + K++
Sbjct: 1391 TQYDMEGENIRRAKNELEKRRHQFALE----VAQHRIEYEEFNEKKKDIEQMNEKATKKL 1446

Query: 1363 QEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHE 1422
            Q+  +L   +EN    K                   +    E    L+ ++  I   + +
Sbjct: 1447 QKAELLK--QENENKLKEIAQNVSEAKQTMLDAEKIKQNADEREKFLKQEEERISNLSKD 1504

Query: 1423 YTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEI 1482
                  + ND       +L   EK+ +++  +      ILR+K        +   KE EI
Sbjct: 1505 AEFNTQKANDIMHKAEDKLAMNEKKEKEIEQKMSEVEKILRMKKDLEEKSLQMSNKEKEI 1564

Query: 1483 ERV--KLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEI 1540
             ++  ++  +LNV + ++ ++  +   L K  +E+  K +E+   L   +I I  +  + 
Sbjct: 1565 VQMMDQVKSKLNV-VEQAQNVKNENENLKKQNDEKDKKISELNHKL---KIAISKIKSD- 1619

Query: 1541 TNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAEL 1589
               QN    S    +  + F +   Q R++ L   ++  LLD   +  L
Sbjct: 1620 QKKQNENGISEVLRRSFLMFVAQDWQHREQMLPGILS--LLDCTDQERL 1666



 Score =  132 bits (319), Expect = 8e-29
 Identities = 191/846 (22%), Positives = 389/846 (45%), Gaps = 102/846 (12%)

Query: 808  EKQKAYSEYTIQEDE-LVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQ 866
            +K KA  + +I   + L N L  +    + +  QL E + E   L K+NQI+ + NQ   
Sbjct: 32   DKHKAQLKQSITNTQILTNELNKVNTEKQSLHDQLTECK-ERLAL-KENQIV-QINQLYA 88

Query: 867  ISLSDMQ--QHYNA-LVEKANRTDLA-ESESTKYQTQLRDLESNLKRITHEHQTLIVQ-- 920
             + +D++  QH NA LV+  N   +  + E+ +  TQL+  E N   ++++  TLI    
Sbjct: 89   QAETDLKNLQHSNAELVQAFNEERMKMKKENAELTTQLKKAEKNNMDLSNDLSTLIENTH 148

Query: 921  -KKKEIEDLEI---EFNTQIESAIRDKKVLNEKYEKN--IEYVTQ-LEAQLQEYKNNIEN 973
             + ++IEDL+    E  T  +     +KV+ E+ EKN  +E  T  L+ QL   KNN  +
Sbjct: 149  DESEKIEDLQEKVKELETLKKQLEESEKVILEEGEKNQLLENETNNLKQQLSNSKNN-SD 207

Query: 974  LNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKIN 1033
            L   ++EL  MN EL  K+ Q Q+            +I + N+     DE  I     ++
Sbjct: 208  LQNAMDELISMNEELTSKNEQLQK------------QIQEFNSKSSTNDEAAITT---LS 252

Query: 1034 NAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILV-REQDDQI 1092
            N  +S  + +++ ++ + +   K+E+++ E+    K+L   +++N  LQ     E+D  I
Sbjct: 253  NENISLSNQITERDATIEELLQKIESIQSELDSKQKELQQLQENNANLQSSNDSEKDSMI 312

Query: 1093 KEL--KETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEF 1150
            ++L  K  +L  E+ +   E   +S+T +       N++             K +E  + 
Sbjct: 313  EDLIRKTDELQKEIGLKSEE---LSTTKKDYESKLQNLESKLSELQISMDS-KTKEVSDL 368

Query: 1151 -----IQERSVLQEQSA--KLNTELQECYTKIIQ----LETLNTELTG--HDVVNQEQIN 1197
                 ++E ++ +  +A  ++++EL+     +++    ++  +TE+T    ++ + +++N
Sbjct: 369  QSQLQLKENAISESSNATTQISSELERLNGIVLRNNELIQQKDTEITKTKQELEDLQKLN 428

Query: 1198 -QLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEH- 1255
             +LKSK+ +L   N+ L+S ++EL+       ++   EI  +  Q L Q     ++ E  
Sbjct: 429  DKLKSKINELTETNNKLVSDLSELQQMSKETEEKLKSEIESIQSQ-LNQTNVMLKEKEGS 487

Query: 1256 --ELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKL-----QDKEEHLRN 1308
              +   Q+S  + +Y  +   VQ   + E N  + M QV  L NK+     Q+ E+  + 
Sbjct: 488  QIQFDSQISEIQKRYNDI--EVQLKEKLEANTSL-MNQVEELSNKVEYYEKQNFEKRNQE 544

Query: 1309 LQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSY-KQMQEQSI 1367
            L+   + + ++ +  +S+ E + +                  D  T    Y  ++ E+  
Sbjct: 545  LEANLSAITSEYQSYKSQSEQKILDIQQKLDKTNNNLEKLQKDHETSKDEYHNELNEKEA 604

Query: 1368 L--NINEENAQLKKSSXXXXXXXXXXXXRVND---AEAKVLELTHQL-ELKDSEIYQKTH 1421
            L  ++ EEN+ + +              ++N     E K  ++  QL   K+ +I +  +
Sbjct: 605  LISSLKEENSSINQRLQQISNENKELMSQINSQLSGEEKSKQIIEQLTNEKNKQIQELQN 664

Query: 1422 EYTITLTQRNDEFENVRQQLVEYEK-------RIEDLTYEKESELA----------ILRL 1464
            +      QRN++ + ++ + VE+ K       +I ++  EKE +L           IL  
Sbjct: 665  KVNSLNQQRNNDKQALKTRAVEFFKNEKQQFDQILNIISEKEQKLGQMSEQMAKKLILVR 724

Query: 1465 KMHENANHYETMQKE--SEIERVKL-IEELNVKITESVSLNKQV--------AELNKALE 1513
            ++ E +   E ++ E  S+++ V+  ++ELN  +    + NKQ+        +EL + +E
Sbjct: 725  RLQEYSIETEKLKDEVTSQLDIVQQKVKELNQIVENDDATNKQILEEKEQIISELEQKIE 784

Query: 1514 EEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLD 1573
            E  +   E+  ++  +E +I  LN ++  +QN +    S+    ++   D  + + E+++
Sbjct: 785  ELESANEELGNSINEKEEDINNLNTKLNEIQNQISQKDSEENNEITKLKDENRTQLEKIN 844

Query: 1574 NTMNKE 1579
            N + KE
Sbjct: 845  N-LEKE 849



 Score =  118 bits (284), Expect = 1e-24
 Identities = 183/913 (20%), Positives = 377/913 (41%), Gaps = 80/913 (8%)

Query: 686  KLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEK------ISELLAKI 739
            K D + +   ++ L+   +    +L+  I     LT++L K++ EK      ++E   ++
Sbjct: 14   KADIDTMRKMLRVLKEKNDKHKAQLKQSITNTQILTNELNKVNTEKQSLHDQLTECKERL 73

Query: 740  NHEEQSKIQ-TQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERK 798
              +E   +Q  Q    A+   ++L   N E   +  + R+   +E+  +    +     K
Sbjct: 74   ALKENQIVQINQLYAQAETDLKNLQHSNAELVQAFNEERMKMKKENAELTTQLK-----K 128

Query: 799  ADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQIL 858
            A++    L        E T  E E +  L   +     ++KQL E E    E  +KNQ+L
Sbjct: 129  AEKNNMDLSNDLSTLIENTHDESEKIEDLQEKVKELETLKKQLEESEKVILEEGEKNQLL 188

Query: 859  LEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLI 918
              E  NL+  LS+ +          N +DL        Q  + +L S  + +T +++   
Sbjct: 189  ENETNNLKQQLSNSK----------NNSDL--------QNAMDELISMNEELTSKNE--- 227

Query: 919  VQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNV 978
             Q +K+I++   + +T  E+AI    + NE    +   +T+ +A ++E    IE++   +
Sbjct: 228  -QLQKQIQEFNSKSSTNDEAAI--TTLSNENISLS-NQITERDATIEELLQKIESIQSEL 283

Query: 979  EELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVS 1038
            +   K   +L + +   Q +   +      + I K + L K    EI   +++++  +  
Sbjct: 284  DSKQKELQQLQENNANLQSSNDSEKDSMIEDLIRKTDELQK----EIGLKSEELSTTKKD 339

Query: 1039 YMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKET 1098
            Y S + + ESKL++    +++  +E+  +  QL   +    E      +   +++ L   
Sbjct: 340  YESKLQNLESKLSELQISMDSKTKEVSDLQSQLQLKENAISESSNATTQISSELERLNGI 399

Query: 1099 KLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQ 1158
             L     I + +  I  +  E       N               K+  +   +Q+ S  +
Sbjct: 400  VLRNNELIQQKDTEITKTKQELEDLQKLNDKLKSKINELTETNNKLVSDLSELQQMS--K 457

Query: 1159 EQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVA 1218
            E   KL +E++   +++ Q   +  E  G  +    QI++++ +   +  +    L    
Sbjct: 458  ETEEKLKSEIESIQSQLNQTNVMLKEKEGSQIQFDSQISEIQKRYNDIEVQ----LKEKL 513

Query: 1219 ELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSS 1278
            E  +S+ + V++   ++    KQ       +F+K   EL   LSA  S+Y       QS 
Sbjct: 514  EANTSLMNQVEELSNKVEYYEKQ-------NFEKRNQELEANLSAITSEY-------QSY 559

Query: 1279 TQEETNKIVTMEQ-VTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXX 1337
              +   KI+ ++Q +    N L+  ++     +++Y + +N+ E L S +++E  +    
Sbjct: 560  KSQSEQKILDIQQKLDKTNNNLEKLQKDHETSKDEYHNELNEKEALISSLKEENSSINQR 619

Query: 1338 XXXXXXXXXXXXXDLRTENQSYKQMQEQSILNI-NEENAQLKKSSXXXXXXXXXXXXRVN 1396
                          + ++  S ++  +Q I  + NE+N Q+++                 
Sbjct: 620  LQQISNENKELMSQINSQ-LSGEEKSKQIIEQLTNEKNKQIQELQNKVNSLNQQRNNDKQ 678

Query: 1397 DAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFEN---VRQQLVEYEKRIEDLTY 1453
              + + +E     + +  +I     E    L Q +++      + ++L EY    E L  
Sbjct: 679  ALKTRAVEFFKNEKQQFDQILNIISEKEQKLGQMSEQMAKKLILVRRLQEYSIETEKLKD 738

Query: 1454 EKESELAILRLK---MHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNK 1510
            E  S+L I++ K   +++   + +   K+   E+ ++I EL  KI E  S N+++     
Sbjct: 739  EVTSQLDIVQQKVKELNQIVENDDATNKQILEEKEQIISELEQKIEELESANEELGNSIN 798

Query: 1511 ALEEEV----AKTNEMQTALENQEI----EIVTLNDE-ITNLQNMVRASSSKIQKHVSFA 1561
              EE++     K NE+Q  +  ++     EI  L DE  T L+ +      K    +S  
Sbjct: 799  EKEEDINNLNTKLNEIQNQISQKDSEENNEITKLKDENRTQLEKINNLEKEKENLQIS-V 857

Query: 1562 SDTKQGRDEQLDN 1574
            S  K+  +EQLD+
Sbjct: 858  SQVKKQLEEQLDS 870


>UniRef50_A2F3I9 Cluster: Viral A-type inclusion protein, putative;
            n=1; Trichomonas vaginalis G3|Rep: Viral A-type inclusion
            protein, putative - Trichomonas vaginalis G3
          Length = 1798

 Score =  169 bits (412), Expect = 4e-40
 Identities = 283/1372 (20%), Positives = 583/1372 (42%), Gaps = 134/1372 (9%)

Query: 217  QMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQ 276
            Q+T++       E E+  +   LL +  +    +S LE  N        +++ E+S+L +
Sbjct: 252  QLTELNTKLQKAEQEYNSKLNNLLIENNTNKSNLSQLELKNT-------QLNNENSQLKK 304

Query: 277  ELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNC 336
            +L +              L  Q ++   E  T  E+   +    +++L  + E L ++  
Sbjct: 305  DLSEFSKTLTSKELEASNLRDQ-LKKVSESNTNREDSKQI----ISQLQDQAEQLRNIIK 359

Query: 337  QIRQTNKELENKLATMGTE-SKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLN 395
                 NK+LE K      + S+A+S  +K     I++    N   K+++   QL  + L+
Sbjct: 360  AKEDENKKLETKNQRAALKYSEAISKLTKSSDDQITKIDQENM--KLQAQL-QLYQQELS 416

Query: 396  QDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLE 455
            +      +K+EI+ L+  ++   K + +    +++  T           KD  I  L   
Sbjct: 417  K---VNASKSEISDLKEKLKEREKTIKELSSKLNDITTQSEANMEFERQKDRQIQNL--- 470

Query: 456  HQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQL 515
               H E   L+      +  +E+ K++ +  ++L   +K    K+ +E  K ++E I +L
Sbjct: 471  ---HSEVAKLLV----EQQKSEVIKIEAEKNRKLVKALK----KEKVELDKKSQEVIAKL 519

Query: 516  NDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELE 575
              +I+    N  ++ S  K+K++Q   + +  S   +S+     L+E++  LS  + EL+
Sbjct: 520  QQKINILTNNY-ELISLEKIKMEQTMSS-NLLSVRKESSDTNTYLSEKVTQLSNSLQELK 577

Query: 576  EEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQ-ELHILQ 634
            ++  +L+  L    +     +++    +E+E L          L S + +L   +   ++
Sbjct: 578  KQNKSLKRKLNGLQNDY---NELKSNQVEIEELENENKDRKKKLRSYQNNLTPVKSPKIE 634

Query: 635  QKYDEVEDKLADISQ---LQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQ 691
             +  E++ KL  +     L  DQ+ +E    + ++ I  L+    +     E++  ++E 
Sbjct: 635  DENKELKKKLRGLQNDYNLLKDQI-TENDEENKQKMIRRLTKKLGQSEKQFEDVSKEREV 693

Query: 692  LYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQF 751
            L   I+DL  + E    KL+N   E      ++ K  A+ IS+L        Q +IQ+  
Sbjct: 694  LLARIEDLSEENE----KLRNRSNEG---DAEIVKTQADLISKL--------QQQIQSLS 738

Query: 752  GIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQK 811
                    +D YI ++  E+ + K R+      +   +DR  ++  K   +   + E   
Sbjct: 739  NNPLDFSAKDQYINSLHQEIDELKQRLNENAAKVVTPQDRN-AVPEKEKTIIDMINEDSD 797

Query: 812  AYSEYTIQEDELVNRLA--VLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISL 869
             YSE    ED         ++    R++     E   EN E+    +++LEE  N    +
Sbjct: 798  GYSEEEEAEDSGSEAATKDLVPSRQRMIRLSYDEPNTENAEITSL-KVMLEEKTN---EV 853

Query: 870  SDMQQHYNA-----LVEKANR--TDLAESESTK------YQTQLRDLESNLKRITHEHQT 916
            +D+++  N      L EK N   TDL  + S K         ++ +L++++  +  + + 
Sbjct: 854  NDLKKQINEANDKNLEEKLNEKVTDLKSTLSLKDDIIQRQNDEINELKTHIDSLKSKIEN 913

Query: 917  LIVQK---KKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIEN 973
            LI      +KE E+ E +++ + E    DK  +++ +EK I      E  L+E K   +N
Sbjct: 914  LIATNNINQKETENKEYDYS-ETEQNNEDKNDIDKMFEKKISNAENQE--LEELKAENDN 970

Query: 974  LNMNV----EELNKMNLELIDKHVQKQQTQSPDYTEQYIN---EINKLNALLKQKDEEII 1026
            L + +     ++     E I K+ ++++ +     ++  N   E+ KLN +L +K  +  
Sbjct: 971  LKIEIIPLKSKVESNENEFIYKNDEEEEVKENADKQEIQNLREEVAKLNDILSRKPSDEY 1030

Query: 1027 ALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQI--- 1083
              NQ   N   S   ++   ++K+A+        E + +  ++   +  ++ EEL+    
Sbjct: 1031 IENQL--NTINSQKQLIDRLQTKVAKLKNSANYSESDDESKTQTKSERNENPEELKTEVE 1088

Query: 1084 LVREQ------DDQIKELKETKLTFEMNIPKTEGMI--ISSTIEPMSDDANNVDXXXXXX 1135
            L+R Q      +D +K+LKET    +  I + +  I  + S IE     ANN +      
Sbjct: 1089 LLRLQLSKLPTEDDMKKLKETIQEKDDKISELQNHITNLKSKIENYVQMANNSNKDNDDK 1148

Query: 1136 XXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQ 1195
                   +  ++EE   E +V       L  + +E   K+++ ++   EL   +   ++Q
Sbjct: 1149 ENDYQYEEYDDDEEVKVEGNVKSRDVVILGNDEEE-EIKVVEGKS---ELEDENENLKKQ 1204

Query: 1196 INQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEH 1255
            I+ LK++L  L  E+DN  S+ +E         D++  +  +  ++ L+Q+E + Q    
Sbjct: 1205 IDDLKNQLRNLQKESDNSTSSDSES--------DEKQNQKEKDTEEKLSQKEEENQL--- 1253

Query: 1256 ELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYAD 1315
             L+ ++S  E K  QL  ++Q+   EE      +E + +   KL  + E L++  +    
Sbjct: 1254 -LKAKISELEEKENQLKITLQNKHSEED-----LENIKNEVQKLNQENEILKSKIDDQQK 1307

Query: 1316 VINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENA 1375
            +I  IE+  +   ++++                   L+ E ++ K   E+S  + + ++ 
Sbjct: 1308 II--IELSNTAQNEQEL---NDLKSENNKNQLLITSLQQEIENLKAKNEKSSSSSSSDDE 1362

Query: 1376 QLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFE 1435
            +  K                  +E +  E    +  KDSEI     E     T+RN+   
Sbjct: 1363 KENKDEEIEILKKEIETLNGTISEKQNFETL--ISEKDSEIESLKKEIQSIETERNNNLS 1420

Query: 1436 NVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHY--ETMQKESEIERVKLIEELNV 1493
               Q++   +K IE +  +K    +  +LK+ +       E  + + E+      EE++ 
Sbjct: 1421 GKEQEIENLKKEIETMKSDKSDSESEEKLKLEDQIKQKDEEIGRLQKELSEKPSNEEISE 1480

Query: 1494 KITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQN 1545
            +I   +   ++ ++L   L    +  NE++  LE +E  ++++  EI NL++
Sbjct: 1481 QIQTILKQGEENSKLQSQLLSMTSMVNEIKAQLEQKENLVISMETEIQNLKS 1532



 Score =  140 bits (340), Expect = 2e-31
 Identities = 267/1334 (20%), Positives = 554/1334 (41%), Gaps = 112/1334 (8%)

Query: 303  SCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSP 362
            SC    E  E+ ++   +++   K    +  L   I   NKE+ N+L     +      P
Sbjct: 185  SCISIVEYLEQ-NIRKKDLSSSPKHDRSISELQAIIDLRNKEI-NELRIQLDDQNKNGKP 242

Query: 363  SKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLV 422
             K+   L+S+ +  NT  K++    + +S+  N   +   NK+ +++LE+    LN +  
Sbjct: 243  DKEKEILLSQLTELNT--KLQKAEQEYNSKLNNLLIENNTNKSNLSQLELKNTQLNNENS 300

Query: 423  DKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLI-HVGTNTEDVNEI--A 479
              +  +SE                  + ++   +    +   +I  +    E +  I  A
Sbjct: 301  QLKKDLSEFSKTLTSKELEASNLRDQLKKVSESNTNREDSKQIISQLQDQAEQLRNIIKA 360

Query: 480  KVQEQLKQELNDEIKDVNVKDLIEKL-KSAEEQITQLNDEIDAANKNMIKVKSNHKLKLK 538
            K  E  K E  ++   +   + I KL KS+++QIT+++ E      NM K+++  +L  +
Sbjct: 361  KEDENKKLETKNQRAALKYSEAISKLTKSSDDQITKIDQE------NM-KLQAQLQLYQQ 413

Query: 539  QMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELE-EEKGNLQLHLVDYDSGRMIESD 597
            ++ K   + S++SD  +++    + +  LS K+ ++  + + N++         + + S+
Sbjct: 414  ELSKVNASKSEISDLKEKLKEREKTIKELSSKLNDITTQSEANMEFERQKDRQIQNLHSE 473

Query: 598  VYKKMIEMENL------AETRLKAISLLESQKFDLVQE----LHILQQKYDEVED--KLA 645
            V K ++E +        AE   K +  L+ +K +L ++    +  LQQK + + +  +L 
Sbjct: 474  VAKLLVEQQKSEVIKIEAEKNRKLVKALKKEKVELDKKSQEVIAKLQQKINILTNNYELI 533

Query: 646  DISQLQSDQ-VCSEIKSVHLEEQIDALSASKK--ELALVIENLKLDKEQLYGTIKDLEND 702
             + +++ +Q + S + SV  E        S+K  +L+  ++ LK   + L   +  L+ND
Sbjct: 534  SLEKIKMEQTMSSNLLSVRKESSDTNTYLSEKVTQLSNSLQELKKQNKSLKRKLNGLQND 593

Query: 703  KEDIMN---KLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQE 759
              ++ +   +++    EN D   KL             KI  E +   +   G+      
Sbjct: 594  YNELKSNQVEIEELENENKDRKKKLRSYQNNLTPVKSPKIEDENKELKKKLRGLQNDYNL 653

Query: 760  -RDLYIENIESELSKYKSRICR-LEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYT 817
             +D   EN E    K   R+ + L +S    ED     E    ++    +E +K  +   
Sbjct: 654  LKDQITENDEENKQKMIRRLTKKLGQSEKQFEDVSKEREVLLARIEDLSEENEKLRNRSN 713

Query: 818  IQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYN 877
              + E+V   A L+     +++Q+  + +   +   K+Q +   +Q +      + ++  
Sbjct: 714  EGDAEIVKTQADLISK---LQQQIQSLSNNPLDFSAKDQYINSLHQEIDELKQRLNENAA 770

Query: 878  ALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIE 937
             +V   +R  + E E T       D +                +++E ED   E  T+  
Sbjct: 771  KVVTPQDRNAVPEKEKTIIDMINEDSDG-------------YSEEEEAEDSGSEAATKDL 817

Query: 938  SAIRDKKVLNEKYEKNIEY--VTQLEAQLQEYKNNIENLNMNVEELNKMNLE--LIDKHV 993
               R + +     E N E   +T L+  L+E  N + +L   + E N  NLE  L +K  
Sbjct: 818  VPSRQRMIRLSYDEPNTENAEITSLKVMLEEKTNEVNDLKKQINEANDKNLEEKLNEKVT 877

Query: 994  QKQQTQS--PDYTEQYINEINKLNA---LLKQKDEEIIALNQKINNAQVSYMSMVSDYES 1048
              + T S   D  ++  +EIN+L      LK K E +IA N  IN  +        +Y+ 
Sbjct: 878  DLKSTLSLKDDIIQRQNDEINELKTHIDSLKSKIENLIATNN-INQKETEN----KEYDY 932

Query: 1049 KLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPK 1108
               +   + +N  ++M    K++  S   N+EL+ L  E D+   E+   K   E N  +
Sbjct: 933  SETEQNNEDKNDIDKM--FEKKI--SNAENQELEELKAENDNLKIEIIPLKSKVESN--E 986

Query: 1109 TEGMIISSTIEPMSDDANN--VDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNT 1166
             E +  +   E + ++A+   +             L  +  +E+I+ +        +L  
Sbjct: 987  NEFIYKNDEEEEVKENADKQEIQNLREEVAKLNDILSRKPSDEYIENQLNTINSQKQLID 1046

Query: 1167 ELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSS--- 1223
             LQ   TK+ +L+         D    +  ++     E+L TE + L   +++L +    
Sbjct: 1047 RLQ---TKVAKLKNSANYSESDDESKTQTKSERNENPEELKTEVELLRLQLSKLPTEDDM 1103

Query: 1224 --ISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLD-SVQSSTQ 1280
              +   + ++  +I+EL + H+   ++   K E+ +++  ++ +   ++  D   +    
Sbjct: 1104 KKLKETIQEKDDKISEL-QNHITNLKS---KIENYVQMANNSNKDNDDKENDYQYEEYDD 1159

Query: 1281 EETNKI---VTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXX 1337
            +E  K+   V    V  L N   D+EE ++ ++ K +++ ++ E L+ +I+D K      
Sbjct: 1160 DEEVKVEGNVKSRDVVILGN---DEEEEIKVVEGK-SELEDENENLKKQIDDLKNQLRNL 1215

Query: 1338 XXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVND 1397
                             +NQ  K  +E+  L+  EE  QL K+             ++++
Sbjct: 1216 QKESDNSTSSDSESDEKQNQKEKDTEEK--LSQKEEENQLLKA-------------KISE 1260

Query: 1398 AEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKES 1457
             E K  +L   L+ K SE  +        + + N E E ++ ++ + +K I +L+   ++
Sbjct: 1261 LEEKENQLKITLQNKHSE--EDLENIKNEVQKLNQENEILKSKIDDQQKIIIELSNTAQN 1318

Query: 1458 ELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVA 1517
            E  +  LK   N N       + EIE +K   E +   + S    +   E  + L++E+ 
Sbjct: 1319 EQELNDLKSENNKNQLLITSLQQEIENLKAKNEKSSSSSSSDDEKENKDEEIEILKKEIE 1378

Query: 1518 KTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMN 1577
              N   +  +N E  I   + EI +L+  +++  ++   ++S      +   ++++ TM 
Sbjct: 1379 TLNGTISEKQNFETLISEKDSEIESLKKEIQSIETERNNNLSGKEQEIENLKKEIE-TMK 1437

Query: 1578 KELLDAVPRAELDL 1591
             +  D+    +L L
Sbjct: 1438 SDKSDSESEEKLKL 1451



 Score =  113 bits (273), Expect = 3e-23
 Identities = 284/1504 (18%), Positives = 628/1504 (41%), Gaps = 135/1504 (8%)

Query: 141  LGDVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXX 200
            L  +T L+  +++ +   +     + I   T      ++  K+  +  +N          
Sbjct: 250  LSQLTELNTKLQKAEQEYNSKLNNLLIENNTNKSNLSQLELKNTQLNNENSQLKKDLSEF 309

Query: 201  XXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLL 260
                        + + Q+ K+ E+    E + K    +L    E     I + E+ NK L
Sbjct: 310  SKTLTSKELEASNLRDQLKKVSESNTNRE-DSKQIISQLQDQAEQLRNIIKAKEDENKKL 368

Query: 261  EAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIAN 320
            E      +L++S+   +L +                +  ++   +E +++    S EI++
Sbjct: 369  ETKNQRAALKYSEAISKLTKSSDDQITKIDQENMKLQAQLQLYQQELSKVNASKS-EISD 427

Query: 321  MTELTKKIE-LLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTA 379
            + E  K+ E  ++ L+ ++     + E  +     + + + +   + + L+  +  ++  
Sbjct: 428  LKEKLKEREKTIKELSSKLNDITTQSEANMEFERQKDRQIQNLHSEVAKLLVEQQ-KSEV 486

Query: 380  SKMKSPWSQLSSETLNQDT---DKKINKNEIAKLEMVIQSL--NKDLVDKEYVISEKDTX 434
             K+++  ++   + L ++    DKK ++  IAKL+  I  L  N +L+  E +  E+   
Sbjct: 487  IKIEAEKNRKLVKALKKEKVELDKK-SQEVIAKLQQKINILTNNYELISLEKIKMEQTMS 545

Query: 435  XXXXXXXXXGKDT------LIAQLQLEHQQHMEGPSLIHVGTN--TEDVNEIAKVQEQLK 486
                       DT       + QL    Q+  +    +    N    D NE+   Q ++ 
Sbjct: 546  SNLLSVRKESSDTNTYLSEKVTQLSNSLQELKKQNKSLKRKLNGLQNDYNELKSNQVEI- 604

Query: 487  QELNDEIKDVNVKDLIEKLKSAEEQITQLND-EIDAANKNMIKVKSNHKLKLKQMQKTI- 544
            +EL +E KD       +KL+S +  +T +   +I+  NK + K     KL+  Q    + 
Sbjct: 605  EELENENKDRK-----KKLRSYQNNLTPVKSPKIEDENKELKK-----KLRGLQNDYNLL 654

Query: 545  -DNFSKVSDSNKE--IVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDS------GRMIE 595
             D  ++  + NK+  I RLT++L    ++  ++ +E+  L   + D          R  E
Sbjct: 655  KDQITENDEENKQKMIRRLTKKLGQSEKQFEDVSKEREVLLARIEDLSEENEKLRNRSNE 714

Query: 596  SD--VYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSD 653
             D  + K   ++ +  + +++++S          Q ++ L Q+ DE++ +L   ++  + 
Sbjct: 715  GDAEIVKTQADLISKLQQQIQSLSNNPLDFSAKDQYINSLHQEIDELKQRL---NENAAK 771

Query: 654  QVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMN-KLQN 712
             V  + ++   E++   +    ++     E  + +        KDL   ++ ++      
Sbjct: 772  VVTPQDRNAVPEKEKTIIDMINEDSDGYSEEEEAEDSGSEAATKDLVPSRQRMIRLSYDE 831

Query: 713  YIQENMDLTDKLEKMSAEKISEL--LAKINHEEQSKIQTQFGIDAKIQERDLYIENIESE 770
               EN ++T  L+ M  EK +E+  L K  +E   K      ++ K+ E+   + +++S 
Sbjct: 832  PNTENAEITS-LKVMLEEKTNEVNDLKKQINEANDK-----NLEEKLNEK---VTDLKST 882

Query: 771  LSKYKSRICRLEESIAVMEDRRYSLERKADQL--GSYLQEKQKAYSEYTIQEDELVNRLA 828
            LS     I R  + I  ++    SL+ K + L   + + +K+    EY   E E  N   
Sbjct: 883  LSLKDDIIQRQNDEINELKTHIDSLKSKIENLIATNNINQKETENKEYDYSETEQNNEDK 942

Query: 829  VLMDHDRVVEKQLLEIEHEN-KELQKKNQIL----------LEENQNLQISLSDMQQHYN 877
               D D++ EK++   E++  +EL+ +N  L          +E N+N  I  +D ++   
Sbjct: 943  --NDIDKMFEKKISNAENQELEELKAENDNLKIEIIPLKSKVESNENEFIYKNDEEEEVK 1000

Query: 878  ALVEKANRTDLAESESTKYQTQLRD-----LESNLKRITHEHQTLIVQKKKEIEDLEIEF 932
               +K    +L E  +       R      +E+ L  I  + Q LI + + ++  L+   
Sbjct: 1001 ENADKQEIQNLREEVAKLNDILSRKPSDEYIENQLNTINSQKQ-LIDRLQTKVAKLKNSA 1059

Query: 933  N---TQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEY--KNNIENLNMNVEELNKMNLE 987
            N   +  ES  + K   NE  E+    V  L  QL +   +++++ L   ++E +    E
Sbjct: 1060 NYSESDDESKTQTKSERNENPEELKTEVELLRLQLSKLPTEDDMKKLKETIQEKDDKISE 1119

Query: 988  LIDKHVQKQQTQSPDYTEQYINEINKLN-------ALLKQKDEEIIALNQKINNAQVSYM 1040
            L   H+   +++  +Y  Q  N  NK N          +  D+E + +   + +  V  +
Sbjct: 1120 L-QNHITNLKSKIENYV-QMANNSNKDNDDKENDYQYEEYDDDEEVKVEGNVKSRDVVIL 1177

Query: 1041 SMVSDYESKLAQFTTKLE----NMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELK 1096
                + E K+ +  ++LE    N+++++  +  QL + ++ ++       E D++  + K
Sbjct: 1178 GNDEEEEIKVVEGKSELEDENENLKKQIDDLKNQLRNLQKESDNSTSSDSESDEKQNQ-K 1236

Query: 1097 ETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSV 1156
            E     +++  + E  ++ + I  + +  N +             L+ +  EE ++    
Sbjct: 1237 EKDTEEKLSQKEEENQLLKAKISELEEKENQLKIT----------LQNKHSEEDLEN--- 1283

Query: 1157 LQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLST 1216
            ++ +  KLN E +   +KI   + +  EL+ +   N++++N LKS+    N +N  L+++
Sbjct: 1284 IKNEVQKLNQENEILKSKIDDQQKIIIELS-NTAQNEQELNDLKSE----NNKNQLLITS 1338

Query: 1217 VAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQ 1276
            + +   ++ +  ++     +   ++     E +  K E E      + +  +E L+    
Sbjct: 1339 LQQEIENLKAKNEKSSSSSSSDDEKENKDEEIEILKKEIETLNGTISEKQNFETLISEKD 1398

Query: 1277 SSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIE-DEKVAFX 1335
            S  +    +I ++E  T   N L  KE+ + NL+++    I  ++  +S+ E +EK+   
Sbjct: 1399 SEIESLKKEIQSIE--TERNNNLSGKEQEIENLKKE----IETMKSDKSDSESEEKLKLE 1452

Query: 1336 XXXXXXXXXXXXXXXDLRTENQSYKQMQEQ--SILNINEENAQLKKSSXXXXXXXXXXXX 1393
                           +L +E  S +++ EQ  +IL   EEN++L+               
Sbjct: 1453 DQIKQKDEEIGRLQKEL-SEKPSNEEISEQIQTILKQGEENSKLQSQLLSMTSMVNEIKA 1511

Query: 1394 RVNDAEAKVLELTHQLE-LKD-SEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDL 1451
            ++   E  V+ +  +++ LK  S+  Q +      L ++N+EF    +Q+   ++ I+ L
Sbjct: 1512 QLEQKENLVISMETEIQNLKSKSDNDQLSLLENENLKKQNEEFS---KQISLKDEEIQTL 1568

Query: 1452 TYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKA 1511
              E E    I + K     N  +  +K  + E    +E+ N ++   +S      E+N  
Sbjct: 1569 RNEIEK---INKEKDEILKNQIQESEKSDKSEANSDLEKENAELKRKLSEYSTQEEMNDQ 1625

Query: 1512 LEEEVAKTNEMQTALENQEIEIVT-LNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDE 1570
            ++  ++++ E+   ++ Q + + T +N+E    Q+     S K +         K+  DE
Sbjct: 1626 IQTILSQSEEIDK-MKKQILALTTKINEENQAKQSDEETESLKKENQTLKEELAKKPSDE 1684

Query: 1571 QLDN 1574
            +L++
Sbjct: 1685 ELND 1688



 Score =  112 bits (269), Expect = 9e-23
 Identities = 240/1260 (19%), Positives = 519/1260 (41%), Gaps = 117/1260 (9%)

Query: 145  THLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINE----KDQIIEAKNKATTXXXXXX 200
            T+LS  + +  N+L  L+ + K ++  +  LQ   NE    + +I E +N+         
Sbjct: 560  TYLSEKVTQLSNSLQELKKQNKSLKRKLNGLQNDYNELKSNQVEIEELENENKDRKKKLR 619

Query: 201  XXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLK-DIESKDVRISSLEEANKL 259
                          + +  ++++    ++ ++   K ++ + D E+K   I  L +    
Sbjct: 620  SYQNNLTPVKSPKIEDENKELKKKLRGLQNDYNLLKDQITENDEENKQKMIRRLTKKLGQ 679

Query: 260  LEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIA 319
             E    ++S E   L   +E                  + ++   +  ++++++      
Sbjct: 680  SEKQFEDVSKEREVLLARIEDLSEENEKLRNRSNEGDAEIVKTQADLISKLQQQIQSLSN 739

Query: 320  NMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGS--PLISRKS-GR 376
            N  + + K + +  L+ +I +  + L    A + T     + P K+ +   +I+  S G 
Sbjct: 740  NPLDFSAKDQYINSLHQEIDELKQRLNENAAKVVTPQDRNAVPEKEKTIIDMINEDSDGY 799

Query: 377  NTASKMKSPWSQLSSETLNQDTDKKINKN---------EIAKLEMVIQSLNKDLVDKEYV 427
            +   + +   S+ +++ L     + I  +         EI  L+++++    ++ D +  
Sbjct: 800  SEEEEAEDSGSEAATKDLVPSRQRMIRLSYDEPNTENAEITSLKVMLEEKTNEVNDLKKQ 859

Query: 428  ISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQ 487
            I+E +             D L + L L+            +    +++NE+    + LK 
Sbjct: 860  INEANDKNLEEKLNEKVTD-LKSTLSLKDDI---------IQRQNDEINELKTHIDSLKS 909

Query: 488  ELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMI--KVKSNHKLKLKQMQKTID 545
            ++ + I   N+     + K  +   T+ N+E       M   K+ +    +L++++   D
Sbjct: 910  KIENLIATNNINQKETENKEYDYSETEQNNEDKNDIDKMFEKKISNAENQELEELKAEND 969

Query: 546  NF--------SKVSDSNKEIVRLTEELHHLS-----QKVAELEEEKGNLQLHLVDYDSGR 592
            N         SKV  +  E +   +E   +      Q++  L EE   L   L    S  
Sbjct: 970  NLKIEIIPLKSKVESNENEFIYKNDEEEEVKENADKQEIQNLREEVAKLNDILSRKPSDE 1029

Query: 593  MIESDV-----YKKMIEMENLAETRLK-AISLLESQKFDLVQELHILQQKYDEVEDKLAD 646
             IE+ +      K++I+       +LK + +  ES      Q      +  +E++ ++ +
Sbjct: 1030 YIENQLNTINSQKQLIDRLQTKVAKLKNSANYSESDDESKTQTKSERNENPEELKTEV-E 1088

Query: 647  ISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDI 706
            + +LQ  ++ +E     L+E I        EL   I NLK   E       +   D +D 
Sbjct: 1089 LLRLQLSKLPTEDDMKKLKETIQEKDDKISELQNHITNLKSKIENYVQMANNSNKDNDDK 1148

Query: 707  MNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIEN 766
             N  Q Y + + D   K+E     +   +L     EE   ++ +  ++ + +     I++
Sbjct: 1149 ENDYQ-YEEYDDDEEVKVEGNVKSRDVVILGNDEEEEIKVVEGKSELEDENENLKKQIDD 1207

Query: 767  IESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNR 826
            ++++L   +        S +  ++++   E+  ++  S  +E+ +       + +E  N+
Sbjct: 1208 LKNQLRNLQKESDNSTSSDSESDEKQNQKEKDTEEKLSQKEEENQLLKAKISELEEKENQ 1267

Query: 827  LAVLMDHDRVVEKQLLEIEHENKELQKKNQIL---LEENQNLQISLSDM---QQHYNALV 880
            L + + +    E+ L  I++E ++L ++N+IL   +++ Q + I LS+    +Q  N L 
Sbjct: 1268 LKITLQNKHS-EEDLENIKNEVQKLNQENEILKSKIDDQQKIIIELSNTAQNEQELNDLK 1326

Query: 881  EKANRTDLA------ESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLE--IEF 932
             + N+  L       E E+ K + +     S+           I   KKEIE L   I  
Sbjct: 1327 SENNKNQLLITSLQQEIENLKAKNEKSSSSSSSDDEKENKDEEIEILKKEIETLNGTISE 1386

Query: 933  NTQIESAIRDKKVLNEKYEKNIEYV-TQLEAQLQEYKNNIENLNMNVEEL--------NK 983
                E+ I +K    E  +K I+ + T+    L   +  IENL   +E +        ++
Sbjct: 1387 KQNFETLISEKDSEIESLKKEIQSIETERNNNLSGKEQEIENLKKEIETMKSDKSDSESE 1446

Query: 984  MNLELIDKHVQKQQT---QSPDYTEQYINE--INKLNALLKQKDEEIIALNQKINNAQVS 1038
              L+L D+  QK +       + +E+  NE    ++  +LKQ +E     N K+ +  +S
Sbjct: 1447 EKLKLEDQIKQKDEEIGRLQKELSEKPSNEEISEQIQTILKQGEE-----NSKLQSQLLS 1501

Query: 1039 YMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKET 1098
              SMV++ +++L Q    + +ME E+Q      L SK  N++L +L   +++ +K+  E 
Sbjct: 1502 MTSMVNEIKAQLEQKENLVISMETEIQN-----LKSKSDNDQLSLL---ENENLKKQNE- 1552

Query: 1099 KLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQ 1158
            + + ++++   E   + + IE ++ + + +             ++  E+ +  +  S L+
Sbjct: 1553 EFSKQISLKDEEIQTLRNEIEKINKEKDEI---------LKNQIQESEKSDKSEANSDLE 1603

Query: 1159 EQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQ-EQINQLKSKLEQLNTE--NDNLLS 1215
            +++A+L  +L E  T+    E +N ++    +++Q E+I+++K ++  L T+   +N   
Sbjct: 1604 KENAELKRKLSEYSTQ----EEMNDQI--QTILSQSEEIDKMKKQILALTTKINEENQAK 1657

Query: 1216 TVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSV 1275
               E   S+         E+A+         +     T+ E   +L     K   +++S 
Sbjct: 1658 QSDEETESLKKENQTLKEELAKKPSDEELNDQIQTIMTQSEELDKLRKQIVKLTAMVNSA 1717

Query: 1276 QSSTQEETNKIVTME-----QVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDE 1330
               + ++ NK +  E     Q +S  +   DKE+   N+ E   D  N  EI   E+E E
Sbjct: 1718 PKMSPDDENKKIYDEKDEEKQKSSSSSSSSDKEDEKENVDEIKKDDENDNEI-EKEVEKE 1776


>UniRef50_UPI00006CB352 Cluster: Viral A-type inclusion protein repeat
            containing protein; n=1; Tetrahymena thermophila
            SB210|Rep: Viral A-type inclusion protein repeat
            containing protein - Tetrahymena thermophila SB210
          Length = 3714

 Score =  169 bits (411), Expect = 5e-40
 Identities = 278/1499 (18%), Positives = 661/1499 (44%), Gaps = 130/1499 (8%)

Query: 144  VTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXX 203
            +  LS  + ++   +  L+V++   +T I  LQ+++N+ ++  + KN+            
Sbjct: 1385 IDQLSAKVGKQQKQVEDLEVQLSETQTKIKQLQDQVNDLEEQKQNKNEKLQEKEKELFAV 1444

Query: 204  XXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAA 263
                    ++ + Q+  ++     +E    D  Q+ L  IE K+  +  ++E     E +
Sbjct: 1445 LSKSNEKEQNLENQLEDVRRKLKEVE----DNLQKALNTIEQKETELKLIKERLTKSEKS 1500

Query: 264  RFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTE 323
              ++  E ++ ++E++Q              L +Q+ E     + +  +  S+  +   E
Sbjct: 1501 EKKLEKERNQKSEEVQQQQKDVEQLQQRVQILEQQNSEYGKIIQGKSNDYDSIIKSVHKE 1560

Query: 324  LTKKIELLE-HLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKM 382
            L  +IE+++ H     ++ ++  + K      ++K   S  +     +  +  +N   ++
Sbjct: 1561 LNTQIEIVQTHKTLLDKEQSEHEQTKKEFEDWKNKLQKSQEENR---LKTEEIQNIQDQL 1617

Query: 383  KSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVD-KEYVISEKDTXXXXXXXX 441
                ++++S+   ++T K +N N+   L+   + LN++  + K  + S  +         
Sbjct: 1618 IDTQNEINSQ---EETIKNLN-NQYENLQKQNEQLNEEHNNLKSKLTSLNEEYSFKIIRM 1673

Query: 442  XXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDE--IKDVNVK 499
                 TL  +L    Q + +   LI    N   +N I K+ +  +Q +N +  I+D   +
Sbjct: 1674 EETIKTLEEELNQLKQNNYDLQQLIQEKDNLIQIN-ITKINQYEQQIINFQEIIQDQQDQ 1732

Query: 500  DLIEK------LKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDS 553
              I+K       ++ E  + + N+++ A  +  + VK N +      ++T  +F  +   
Sbjct: 1733 AQIQKQQIELQAQTQESTLKKQNEQVIAQIRAEL-VKENLQNIQNCKEETEIHFQNILQE 1791

Query: 554  NKEI--VRLTEELHHLSQKVAELEEE-KGNLQLHLVDYDSGRMIESDVYKKMIEMENLAE 610
             ++   V   +       K+  +++E +  LQ  L + ++ +   + + +K+ E E   +
Sbjct: 1792 KEQQYQVLFQQTTQSYESKIILIQQEFQVILQQKLEELEAAQ--SAILQQKLNEQEAQHQ 1849

Query: 611  TRLKAISLLESQKFDLV----QELHILQQKYDE-VEDKLADISQLQSDQVCSEIKSVHLE 665
              L+   LL++Q+ +L     +E+  L+ +Y E + ++  + +++ S+Q   +I++   +
Sbjct: 1850 KELQ--KLLKNQQNELQSKFQEEMKHLEAQYQEKLNEQSENHNKILSEQA-KQIQNSENQ 1906

Query: 666  EQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQEN-MDLTDKL 724
                 +   + +   ++     + E+++  I  L+   ++     Q  +QE  +++ ++ 
Sbjct: 1907 NLSQKIIDQQTQFEQILSQKLKESEEIHNQI--LQEKIKECEGNFQLILQEKTIEIQNEQ 1964

Query: 725  EKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEES 784
             K+  +K+ E  +++N + Q K+   F      Q+    +E  + +   Y   I   ++ 
Sbjct: 1965 NKVLLDKLKEQESQLNKQIQQKLSADFQ-----QQVQTLVEKQKQQEENYNKIIQEKDQQ 2019

Query: 785  IAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEI 844
            IA M++    L+  + +    LQEK+    E T       N + ++   + +   Q+ +I
Sbjct: 2020 IAKMDE---ILKVNSQEFQQVLQEKEAQILEIT-------NNINIIQQQNNI---QIQQI 2066

Query: 845  EHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRT---DLAESESTKYQTQLR 901
              ++K  Q+ N+I+  +N+  + + S   Q     ++  +R    +  + E  K + ++ 
Sbjct: 2067 NQQHK--QEINEIVSSKNEITKYTKSLEDQIAEQEMKNKDRDQEENQLKQELKKQEDKVH 2124

Query: 902  DLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLE 961
            DL     ++  E + L  Q +  ++ L+ +    I++   D + LNE    + +    L+
Sbjct: 2125 DLTQKYSKLQTELENLKEQHQDYVKQLQNQHLQAIQAKDSDIEKLNENVRNSKKNSQDLQ 2184

Query: 962  AQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTE--QYINEIN-KLNALL 1018
             QLQ  +    NL   + EL  +N +  ++  Q+      +Y+E  Q + + N +   +L
Sbjct: 2185 LQLQSLQQTRHNLEEQLNELRTLNSKSANQQSQQFSQLQDEYSELQQNLQQKNLQFKQML 2244

Query: 1019 KQKDEEIIALNQKINNAQVSY---MSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSK 1075
             + + E   LN+KI   +       ++  ++++ + Q   K++  +++++    Q+   +
Sbjct: 2245 NEHESEKSQLNEKITKIEKQLKDNQTICQEHQNLIEQNNLKIKEQQQKIKEYENQISQMQ 2304

Query: 1076 QHNEE-LQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXX 1134
            Q NEE  +I  +EQ++  KE+++ K   E N  K         I+    + +N+      
Sbjct: 2305 QQNEEQAKIQQKEQNNLDKEIEKLKKHIESN-QKEAAEQQQELIKKHQQEIDNIQNQNDI 2363

Query: 1135 XXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQE 1194
                      Q+ E  IQ+ +  Q++ A+ + +  E   + IQ  T   +    ++V Q 
Sbjct: 2364 HLQQQLNQLKQQYEVQIQQITKQQKEEAQKHNQSSE---QQIQQITAKYQQDIQNIVQQN 2420

Query: 1195 -----QINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREAD 1249
                 ++N+   +L Q +++N   +  + +   + S+  + +  E ++++++ ++Q    
Sbjct: 2421 EQKIAELNEANKQLSQKDSDNQIKIHQLQQESENNSTNFETKISENSKIYEEKISQISIT 2480

Query: 1250 FQKTEHELR----VQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEH 1305
            F+    E++    +Q++  + +YE  + S+Q S +++TN+    E+   L +KL  KEE 
Sbjct: 2481 FETKITEIKQSYEIQINELKQQYETKIQSLQES-EKQTNESSNKEK-QELISKL--KEEF 2536

Query: 1306 LRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQ-SYKQMQE 1364
             + + EK  +   Q++ ++  ++ +   +                + + +++ + K++ E
Sbjct: 2537 QKEIAEKDENHNKQVKEIQDNLDKQINDYESKIKALQVDYQKQIEESKADHEKNIKEITE 2596

Query: 1365 QSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYT 1424
            +    I++ N + +K                 D E   +++ H+  +K  E+ +K    T
Sbjct: 2597 KFEKQISDLNERQQK-----------------DIEG--IQINHEFIIK--ELQKKIETLT 2635

Query: 1425 ITLTQRNDEFEN-VRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHY---ETMQKES 1480
            ITL + N E E+ V +   E E+ I+++  +  S++     +MH++ N Y       ++ 
Sbjct: 2636 ITLDEINQEKEDIVNKAKEEAEQEIQNIDQKYRSQIQ----QMHKDHNDYILNTESDQQD 2691

Query: 1481 EIERVK-----LIEELNVKI-TESVSLNKQVAELNKALEEEVAKTNEMQTAL--ENQEIE 1532
             I+ VK      I+EL   I ++S  L ++     K LEE++ +  +  T    ENQ +E
Sbjct: 2692 AIQTVKEQYELEIQELKQMIPSDSNELIQKYLNQIKELEEKIQQLQQQDTQSNEENQRLE 2751

Query: 1533 IVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDL 1591
            +      I  L+  +    +K Q  +S  S++ +    +++ T NKE +  + R E +L
Sbjct: 2752 LT-----IIQLEEKIIQVENKYQIQLSNESESHKQLIIEIE-TQNKEKIAELQRIENEL 2804



 Score =  160 bits (389), Expect = 3e-37
 Identities = 280/1403 (19%), Positives = 614/1403 (43%), Gaps = 131/1403 (9%)

Query: 214  TKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEE--ANKLLEAARFEISLEH 271
            +KQ M +  ENF  +  + K++++ + K+   +++ +  +E    N   E  +++I  E+
Sbjct: 385  SKQMMQEQSENFKELRKKLKEQEKIINKE---QEIIVKEMERNLKNSKDEQKKYQIQYEN 441

Query: 272  SKL-AQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIEL 330
             K    +++Q                K       +E   I      E+    E+  ++E 
Sbjct: 442  KKKEIIQIKQSLTIQINTLSQQVDSLKSENSLLKQEIQNININRQAELNEFEEVKLQLEN 501

Query: 331  LEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPL---ISRKSGRNTASKMKSPWS 387
             EH   Q+ Q  +E + K+  +  +    S      S L   I+R +  N A+ +K    
Sbjct: 502  AEH---QLFQIQREYQTKIEEVSEKKYENSQNHITVSQLNDQINRLNQEN-ANLLKEKEQ 557

Query: 388  QL----SSETLNQDTDKKINK-NEI-AKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXX 441
             L    S +   ++   K++K NE+  + ++ I+ L+  L DKE  I EK          
Sbjct: 558  VLRKSESDKMRIEEFQLKLSKVNEVQEQYQLEIRQLSVKLADKENEIYEK-MQEIDQLRQ 616

Query: 442  XXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDL 501
                D  I QL+ E+Q  ++  + +H    T  ++ + ++ ++L++ L  +   VNV+ +
Sbjct: 617  ISSNDLEIQQLKEENQNLIDQINQLHEAQQTLAIHNV-QINDELRR-LQQQ-SSVNVQQI 673

Query: 502  IEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLT 561
            I +    +E+ T +  EI+   KN+I     ++ K  Q Q  + NF+      K++  L 
Sbjct: 674  IIEKTQIQERYTYILKEIE--EKNII--IHQYEEKEDQYQAEVMNFT------KQLENLQ 723

Query: 562  EELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLES 621
            E+   ++++  +L  EK    + + D  +    E ++ +K   ++ + + +   I     
Sbjct: 724  EKYDRMNEEFDDLLNEKEQFLIQIQDLQNKCQHEQEINQKY--LDQIGKYKQDDIDQQNR 781

Query: 622  QKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALV 681
            +K    + L  +Q+  D++ D+L+  S+    +   EIK++    Q       ++E A +
Sbjct: 782  EK----KYLKEIQKLKDDI-DQLSKQSKKNQHENNEEIKAMLTSLQTKN-EKLEQENAQI 835

Query: 682  IENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTD----KLE---KMSAEKISE 734
            +++ +  + QL   ++ L     D+ N L   ++E ++  D    +LE   ++SA+KI  
Sbjct: 836  LQSSQEQQNQLLTNLEMLTQQNIDVQNNLA-ILEEEVNQKDLKIQQLEQELQLSAQKIET 894

Query: 735  LLAKINHEEQSK-IQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRY 793
             L+    E + K  Q Q  +  + Q+ ++ I+++++++ K   +I   ++     ++ ++
Sbjct: 895  FLSLAEEENKIKHAQNQALLKQQEQKLEIIIDDLKNKIDKLNQQI---KDQQYENKEVKF 951

Query: 794  SLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQK 853
             LE+  +      ++ QK   +    + ++    A+ +     +++Q+ + E + K  QK
Sbjct: 952  ELEKCRESKKEQEEKLQKQKDKNKELKQKITEIEALSVKQISQLQQQISQYEIQIKNSQK 1011

Query: 854  KNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAES--------ESTKYQTQLRDLES 905
              Q L ++   ++  LS  Q   +   EK++ +  +++        E  KYQ Q+++L++
Sbjct: 1012 VEQDLKDKITEIKEKLSQNQLELSKQKEKSSSSSSSKNVLRSEYIQEIEKYQNQIKELKN 1071

Query: 906  NLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQ 965
            NL             K++E   +  E+N          K+L+ + E+ +E   +++   +
Sbjct: 1072 NLD-----------DKERETRKILTEYNE------ARNKILSYQTEQ-LENEEKIDKLKE 1113

Query: 966  EYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEI 1025
            E K     LN   E ++++  E I K      + S +     I++IN  N+  ++    I
Sbjct: 1114 ELKVKSNKLNQQQETIDQLQQE-IQKKQNIIMSGSNNLNNSQISQING-NSNQRRSLNNI 1171

Query: 1026 IALNQKINNA-QVSYMS-MVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHN-EELQ 1082
            I     INN   VS ++  ++D ++ L +    + N++EE +++       +Q    +L+
Sbjct: 1172 IVDESGINNTNHVSQLNQQINDLQNLLQERENIINNLKEENKQIQDFYHSEQQEKVNQLE 1231

Query: 1083 ILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXL 1142
               ++ ++QIKE ++ K+ ++ +    +    S  I+ ++D    +             L
Sbjct: 1232 NQYQQIENQIKE-RDDKIAYQSSQLDQK----SKEIQQLNDRIKQITSTKDQITQQYSKL 1286

Query: 1143 KVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSK 1202
              QE    + +++V  E +AKL    QE    I++++         D++ Q+  +++K +
Sbjct: 1287 --QENNLKLHDQNV--ELTAKLENFQQEFQKIIVKVKEQEQATNYKDMIIQQLDDKIK-E 1341

Query: 1203 LEQLNTENDNLLSTV-AELRSSISSA-VDQRGFEIAELWKQ----HLAQREADFQKTEHE 1256
            LEQ   E D ++  V +  +  ++ A   Q+  +     KQ     L+ +    QK   +
Sbjct: 1342 LEQEKQEADKVIDKVKSSKKDQLNDAQQQQKNLQANNEQKQALIDQLSAKVGKQQKQVED 1401

Query: 1257 LRVQLSAFESKYEQLLDSVQSSTQEETNKIVTM---------------EQVTSLQNKLQD 1301
            L VQLS  ++K +QL D V    +++ NK   +               E+  +L+N+L+D
Sbjct: 1402 LEVQLSETQTKIKQLQDQVNDLEEQKQNKNEKLQEKEKELFAVLSKSNEKEQNLENQLED 1461

Query: 1302 KEEHLRNLQEKYADVINQIEILRSE---IEDEKVAFXXXXXXXXXXXXXXXXDLRTENQS 1358
                L+ +++     +N IE   +E   I++                     +++ + + 
Sbjct: 1462 VRRKLKEVEDNLQKALNTIEQKETELKLIKERLTKSEKSEKKLEKERNQKSEEVQQQQKD 1521

Query: 1359 YKQMQE--QSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQ--LELKDS 1414
             +Q+Q+  Q +   N E  ++ +              +  + + ++++ TH+  L+ + S
Sbjct: 1522 VEQLQQRVQILEQQNSEYGKIIQGKSNDYDSIIKSVHKELNTQIEIVQ-THKTLLDKEQS 1580

Query: 1415 EIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYE 1474
            E  Q   E+     +     E  R +  E +  I+D   + ++E+      +    N YE
Sbjct: 1581 EHEQTKKEFEDWKNKLQKSQEENRLKTEEIQ-NIQDQLIDTQNEINSQEETIKNLNNQYE 1639

Query: 1475 TMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIV 1534
             +QK++E    +L EE N   ++  SLN++ +     +EE +    E    L+    ++ 
Sbjct: 1640 NLQKQNE----QLNEEHNNLKSKLTSLNEEYSFKIIRMEETIKTLEEELNQLKQNNYDLQ 1695

Query: 1535 TLNDEITNLQNMVRASSSKIQKH 1557
             L   I    N+++ + +KI ++
Sbjct: 1696 QL---IQEKDNLIQINITKINQY 1715



 Score =  152 bits (369), Expect = 7e-35
 Identities = 295/1534 (19%), Positives = 639/1534 (41%), Gaps = 108/1534 (7%)

Query: 90   ISESLANTLKQKEILMEKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSN 149
            +++  AN LK+KE ++ K       S+     I                 QL ++  LS 
Sbjct: 544  LNQENANLLKEKEQVLRK-------SESDKMRIEEFQLKLSKVNEVQEQYQL-EIRQLSV 595

Query: 150  TIKEKDNAL--SVLQV-KMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXX 206
             + +K+N +   + ++ +++ + +  L++Q+   E   +I+  N+               
Sbjct: 596  KLADKENEIYEKMQEIDQLRQISSNDLEIQQLKEENQNLIDQINQLHEAQQTLAIHNVQI 655

Query: 207  XXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAA--R 264
                    +Q    +Q+  I  + + ++    +LK+IE K++ I   EE     +A    
Sbjct: 656  NDELRRLQQQSSVNVQQ-IIIEKTQIQERYTYILKEIEEKNIIIHQYEEKEDQYQAEVMN 714

Query: 265  FEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEK-----GSL--- 316
            F   LE+ +   +                 +  Q ++  C+ + EI +K     G     
Sbjct: 715  FTKQLENLQEKYDRMNEEFDDLLNEKEQFLIQIQDLQNKCQHEQEINQKYLDQIGKYKQD 774

Query: 317  EIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGR 376
            +I       K ++ ++ L   I Q +K+ +        E KA+ +  +  +  + +++ +
Sbjct: 775  DIDQQNREKKYLKEIQKLKDDIDQLSKQSKKNQHENNEEIKAMLTSLQTKNEKLEQENAQ 834

Query: 377  NTASKMKSPWSQLSS-ETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXX 435
               S  +     L++ E L Q      N   I + E+  + L    +++E  +S +    
Sbjct: 835  ILQSSQEQQNQLLTNLEMLTQQNIDVQNNLAILEEEVNQKDLKIQQLEQELQLSAQKIET 894

Query: 436  XXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTED-VNEIAKVQEQLKQELNDEIK 494
                     K        L  QQ  +   +I    N  D +N+  K Q+   +E+  E++
Sbjct: 895  FLSLAEEENKIKHAQNQALLKQQEQKLEIIIDDLKNKIDKLNQQIKDQQYENKEVKFELE 954

Query: 495  DV--NVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSD 552
                + K+  EKL+  +++  +L  +I       +K  S  + ++ Q +  I N  KV  
Sbjct: 955  KCRESKKEQEEKLQKQKDKNKELKQKITEIEALSVKQISQLQQQISQYEIQIKNSQKVEQ 1014

Query: 553  SNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETR 612
              K+  ++TE    LSQ   EL ++K   +       S  ++ S+  +++ + +N     
Sbjct: 1015 DLKD--KITEIKEKLSQNQLELSKQK---EKSSSSSSSKNVLRSEYIQEIEKYQN----- 1064

Query: 613  LKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALS 672
               I  L++   D  +E   +  +Y+E  +K   I   Q++Q+ +E K   L+E++   S
Sbjct: 1065 --QIKELKNNLDDKERETRKILTEYNEARNK---ILSYQTEQLENEEKIDKLKEELKVKS 1119

Query: 673  ASKKELALVIENLK--LDKEQ--LYGTIKDLENDKEDIMNKLQNYIQE-NMDLTDKLEKM 727
                +    I+ L+  + K+Q  +     +L N +   +N   N  +  N  + D+    
Sbjct: 1120 NKLNQQQETIDQLQQEIQKKQNIIMSGSNNLNNSQISQINGNSNQRRSLNNIIVDESGIN 1179

Query: 728  SAEKISELLAKINHEEQSKIQTQFGIDAKIQE-----RDLYIENIESELSKYKSRICRLE 782
            +   +S+L  +IN + Q+ +Q +  I   ++E     +D Y    + ++++ +++  ++E
Sbjct: 1180 NTNHVSQLNQQIN-DLQNLLQERENIINNLKEENKQIQDFYHSEQQEKVNQLENQYQQIE 1238

Query: 783  ESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLL 842
              I   +D+      + DQ    +Q+      + T  +D++  + + L +++  +  Q +
Sbjct: 1239 NQIKERDDKIAYQSSQLDQKSKEIQQLNDRIKQITSTKDQITQQYSKLQENNLKLHDQNV 1298

Query: 843  EIEHENKELQKKNQ--ILLEENQNLQISLSDM--QQHYNALVEKANRTDLAESESTKYQT 898
            E+  + +  Q++ Q  I+  + Q    +  DM  QQ  + + E       A+    K ++
Sbjct: 1299 ELTAKLENFQQEFQKIIVKVKEQEQATNYKDMIIQQLDDKIKELEQEKQEADKVIDKVKS 1358

Query: 899  QLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKV-LNEKYEKNIEYV 957
              +D  ++ ++     Q    QK+  I+ L  +   Q +  + D +V L+E   K    +
Sbjct: 1359 SKKDQLNDAQQQQKNLQANNEQKQALIDQLSAKVGKQ-QKQVEDLEVQLSETQTK----I 1413

Query: 958  TQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQ---TQSPDY---TEQYINEI 1011
             QL+ Q+ + +   +N N  ++E  K    ++ K  +K+Q    Q  D     ++  + +
Sbjct: 1414 KQLQDQVNDLEEQKQNKNEKLQEKEKELFAVLSKSNEKEQNLENQLEDVRRKLKEVEDNL 1473

Query: 1012 NKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQL 1071
             K    ++QK+ E+  + +++  ++ S   +  +   K  +   + +++E+  QRV    
Sbjct: 1474 QKALNTIEQKETELKLIKERLTKSEKSEKKLEKERNQKSEEVQQQQKDVEQLQQRVQILE 1533

Query: 1072 LDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXX 1131
              + ++ + +Q    + D  IK + + +L  ++ I +T   ++        + + +    
Sbjct: 1534 QQNSEYGKIIQGKSNDYDSIIKSVHK-ELNTQIEIVQTHKTLLD------KEQSEHEQTK 1586

Query: 1132 XXXXXXXXXXLKVQEEEEF-IQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDV 1190
                       K QEE     +E   +Q+Q      E+      I  L      L   + 
Sbjct: 1587 KEFEDWKNKLQKSQEENRLKTEEIQNIQDQLIDTQNEINSQEETIKNLNNQYENLQKQNE 1646

Query: 1191 VNQEQINQLKSKLEQLNTEND----NLLSTVAELRSSISSAVDQRGFEIAEL--WKQHLA 1244
               E+ N LKSKL  LN E       +  T+  L   ++  + Q  +++ +L   K +L 
Sbjct: 1647 QLNEEHNNLKSKLTSLNEEYSFKIIRMEETIKTLEEELNQ-LKQNNYDLQQLIQEKDNLI 1705

Query: 1245 Q------READFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNK 1298
            Q       + + Q    +  +Q    +++ ++    +Q+ TQE T K    + +  ++ +
Sbjct: 1706 QINITKINQYEQQIINFQEIIQDQQDQAQIQKQQIELQAQTQESTLKKQNEQVIAQIRAE 1765

Query: 1299 LQDKEEHLRNLQE-KYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRT-EN 1356
            L   +E+L+N+Q  K    I+   IL+ + +  +V F                + +    
Sbjct: 1766 L--VKENLQNIQNCKEETEIHFQNILQEKEQQYQVLFQQTTQSYESKIILIQQEFQVILQ 1823

Query: 1357 QSYKQMQ--EQSIL--NINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELK 1412
            Q  ++++  + +IL   +NE+ AQ +K                   E K LE  +Q +L 
Sbjct: 1824 QKLEELEAAQSAILQQKLNEQEAQHQKELQKLLKNQQNELQSKFQEEMKHLEAQYQEKLN 1883

Query: 1413 D-SEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYE--KESE---LAILRLKM 1466
            + SE + K         Q N E +N+ Q++++ + + E +  +  KESE     IL+ K+
Sbjct: 1884 EQSENHNKILSEQAKQIQ-NSENQNLSQKIIDQQTQFEQILSQKLKESEEIHNQILQEKI 1942

Query: 1467 HENANHYETMQKESEIE-RVKLIEELNVKITESVS-LNKQVAE-LNKALEEEVAKTNEMQ 1523
             E   +++ + +E  IE + +  + L  K+ E  S LNKQ+ + L+   +++V    E Q
Sbjct: 1943 KECEGNFQLILQEKTIEIQNEQNKVLLDKLKEQESQLNKQIQQKLSADFQQQVQTLVEKQ 2002

Query: 1524 TALENQEIEIVTLND-EITNLQNMVRASSSKIQK 1556
               E    +I+   D +I  +  +++ +S + Q+
Sbjct: 2003 KQQEENYNKIIQEKDQQIAKMDEILKVNSQEFQQ 2036



 Score =  140 bits (338), Expect = 4e-31
 Identities = 232/1276 (18%), Positives = 559/1276 (43%), Gaps = 109/1276 (8%)

Query: 319  ANMTELTKKIELLEHLN-CQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRN 377
            A + E+T  I +++  N  QI+Q N++ + ++  + +    ++  +K     I+ +  +N
Sbjct: 2043 AQILEITNNINIIQQQNNIQIQQINQQHKQEINEIVSSKNEITKYTKSLEDQIAEQEMKN 2102

Query: 378  TASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXX 437
                 +   +QL  E   Q+        + +KL+  +++L +    ++YV   ++     
Sbjct: 2103 KDRDQEE--NQLKQELKKQEDKVHDLTQKYSKLQTELENLKEQ--HQDYVKQLQNQHLQA 2158

Query: 438  XXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVN 497
                   KD+ I +L    +   +    + +      +  + + +  L+++LN E++ +N
Sbjct: 2159 IQA----KDSDIEKLNENVRNSKKNSQDLQL-----QLQSLQQTRHNLEEQLN-ELRTLN 2208

Query: 498  VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEI 557
             K   ++     +Q +QL DE     +N+        L+ KQM    ++ S+ S  N++I
Sbjct: 2209 SKSANQQ----SQQFSQLQDEYSELQQNL----QQKNLQFKQMLN--EHESEKSQLNEKI 2258

Query: 558  VRLTEELHHLSQKVAELEE---EKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLK 614
             ++ ++L   +Q + +  +   E+ NL++        +  E+ + +   + E  A+ + K
Sbjct: 2259 TKIEKQLKD-NQTICQEHQNLIEQNNLKIK-EQQQKIKEYENQISQMQQQNEEQAKIQQK 2316

Query: 615  AISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSAS 674
              + L+ +   L + +   Q++  E + +L    Q + D + ++   +HL++Q++ L   
Sbjct: 2317 EQNNLDKEIEKLKKHIESNQKEAAEQQQELIKKHQQEIDNIQNQ-NDIHLQQQLNQL--- 2372

Query: 675  KKELALVIENL-KLDKEQLYGTIKDLENDKEDIMNK----LQNYIQENMDLTDKLE---K 726
            K++  + I+ + K  KE+     +  E   + I  K    +QN +Q+N     +L    K
Sbjct: 2373 KQQYEVQIQQITKQQKEEAQKHNQSSEQQIQQITAKYQQDIQNIVQQNEQKIAELNEANK 2432

Query: 727  MSAEKISELLAKINHEEQSKIQTQFGIDAKIQERD-LYIENIESELSKYKSRICRLEESI 785
              ++K S+   KI+  +Q         + KI E   +Y E I      ++++I  +++S 
Sbjct: 2433 QLSQKDSDNQIKIHQLQQESENNSTNFETKISENSKIYEEKISQISITFETKITEIKQSY 2492

Query: 786  AVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQE-DELVNRLAVLMDHDRVVEKQLLEI 844
             +  +    L+++ +     LQE +K  +E + +E  EL+++L      + + EK     
Sbjct: 2493 EIQINE---LKQQYETKIQSLQESEKQTNESSNKEKQELISKLKEEFQKE-IAEKD---- 2544

Query: 845  EHENKELQKKNQILLEENQNLQISLSDMQQHYNALVE--KANRTDLAESESTKYQTQLRD 902
            E+ NK++++    L ++  + +  +  +Q  Y   +E  KA+     +  + K++ Q+ D
Sbjct: 2545 ENHNKQVKEIQDNLDKQINDYESKIKALQVDYQKQIEESKADHEKNIKEITEKFEKQISD 2604

Query: 903  L----ESNLKRITHEHQTLIVQKKKEIEDLEI---EFNTQIESAIRDKKVLNEKYEKNIE 955
            L    + +++ I   H+ +I + +K+IE L I   E N + E  +   K   E+  +NI+
Sbjct: 2605 LNERQQKDIEGIQINHEFIIKELQKKIETLTITLDEINQEKEDIVNKAKEEAEQEIQNID 2664

Query: 956  --YVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSP----DYTEQYIN 1009
              Y +Q++   +++ + I N   + ++  +   E  +  +Q+ +   P    +  ++Y+N
Sbjct: 2665 QKYRSQIQQMHKDHNDYILNTESDQQDAIQTVKEQYELEIQELKQMIPSDSNELIQKYLN 2724

Query: 1010 EINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSK 1069
            +I +L   ++Q  ++    N++    +++ + +         ++  +L N  E  +++  
Sbjct: 2725 QIKELEEKIQQLQQQDTQSNEENQRLELTIIQLEEKIIQVENKYQIQLSNESESHKQLII 2784

Query: 1070 QL-LDSKQHNEELQILVREQDDQIKEL----KETKLTFEMNIPKTEGMIISSTIEPMSDD 1124
            ++   +K+   ELQ +  E   QI  L    ++ K+  +  I + +G      I  +  +
Sbjct: 2785 EIETQNKEKIAELQRIENELRIQIASLLGMDEKQKVDQQQKINQ-QGADKEQQIVILQKE 2843

Query: 1125 ANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKI-IQLETLNT 1183
             + ++            L++QE E+ IQ+   +Q + ++  ++L + Y  I ++ E L +
Sbjct: 2844 IHTIESTYQ--------LRIQEFEKQIQD---IQLRESQRYSQLAQRYLLICLESERLKS 2892

Query: 1184 ELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRS--SISSAVDQRGFEIAELWKQ 1241
                 +  +    +Q +S++ +L  +  N +  +++L+   +ISS    +  +  ++++Q
Sbjct: 2893 SANERNSSSGSNTSQYQSRINELEIQIQNHIEVISKLQQELNISSTTINQQIQKIQIYEQ 2952

Query: 1242 HLAQRE-ADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQ 1300
             +      D    +  L V L A   +  Q+  +  S +   +N+ V  ++   + +KLQ
Sbjct: 2953 QIQSNNFTDQNLLQKYLIVCLEA--ERLRQVALNQSSKSMAVSNQPVDFDKDQQI-SKLQ 3009

Query: 1301 DKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYK 1360
             + +   +   +    IN  + L S++E E                        + Q   
Sbjct: 3010 IQVQQYEHKMSELLITINSKQELISKLETEINIHIEKVSILNQQMQSQQTQSSVDTQL-- 3067

Query: 1361 QMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKT 1420
             +Q+  I+ +  E  +L+K +             +   + +V++L  ++  K   I +  
Sbjct: 3068 -LQKYLIVCLEAERLKLQKGTSGISIQQNFNDSEIEILKQRVIQLEQEVIYKSQIISEFE 3126

Query: 1421 HEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKES 1480
                +  + ++ + + + QQ +      E L  + + + A      +EN    E ++K+ 
Sbjct: 3127 ESKGVKRSTKSSQNQELSQQYLVVCMEAERLQQQLQKQKAD-----YENQIS-ELIKKDK 3180

Query: 1481 EIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEI 1540
              +    I +  +K     +LN+++    K+  +   K+N      E+Q+ +I  +  ++
Sbjct: 3181 RNQEYLKINDAQIK-----ALNEKL----KSSSQSSLKSNPSSPVNEDQDNKIKEIQAKL 3231

Query: 1541 TNLQNMVRASSSKIQK 1556
               Q  + +   KI+K
Sbjct: 3232 EKAQMQIESQMQKIEK 3247



 Score =  122 bits (293), Expect = 1e-25
 Identities = 276/1384 (19%), Positives = 609/1384 (44%), Gaps = 129/1384 (9%)

Query: 214  TKQQMTKMQENFIAMEAEWKDEKQRLLKDIES----KDVRISSLEEANKLLEAARFEISL 269
            TKQQ  + Q++  + E + +    +  +DI++     + +I+ L EANK L     +  +
Sbjct: 2384 TKQQKEEAQKHNQSSEQQIQQITAKYQQDIQNIVQQNEQKIAELNEANKQLSQKDSDNQI 2443

Query: 270  EHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIE 329
            +  +L QE E                   + E    E ++I E+   +I+ +T  TK  E
Sbjct: 2444 KIHQLQQESENNST---------------NFETKISENSKIYEEKISQIS-ITFETKITE 2487

Query: 330  LLEHLNCQIRQTNKELENKLATMGTESKAVS-SPSKKGSPLISR---KSGRNTASKMKSP 385
            + +    QI +  ++ E K+ ++    K  + S +K+   LIS+   +  +  A K ++ 
Sbjct: 2488 IKQSYEIQINELKQQYETKIQSLQESEKQTNESSNKEKQELISKLKEEFQKEIAEKDENH 2547

Query: 386  WSQLSSETLNQDTDKKIN--KNEIAKLEMVIQS-LNKDLVDKEY---VISEKDTXXXXXX 439
              Q+    +  + DK+IN  +++I  L++  Q  + +   D E     I+EK        
Sbjct: 2548 NKQVKE--IQDNLDKQINDYESKIKALQVDYQKQIEESKADHEKNIKEITEKFEKQISDL 2605

Query: 440  XXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVK 499
                 KD  I  +Q+ H+  ++      + T T  ++EI + +E +  +  +E +   ++
Sbjct: 2606 NERQQKD--IEGIQINHEFIIKELQK-KIETLTITLDEINQEKEDIVNKAKEEAEQ-EIQ 2661

Query: 500  DLIEKLKSAEEQITQ------LNDEIDAANKNMIKVKSNHKLKLKQMQKTI--DNFSKVS 551
            ++ +K +S  +Q+ +      LN E D  +  +  VK  ++L+++++++ I  D+   + 
Sbjct: 2662 NIDQKYRSQIQQMHKDHNDYILNTESDQQDA-IQTVKEQYELEIQELKQMIPSDSNELIQ 2720

Query: 552  DSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAET 611
                +I  L E++  L Q+  +  EE   L+L ++  +  ++I+ +  K  I++ N +E+
Sbjct: 2721 KYLNQIKELEEKIQQLQQQDTQSNEENQRLELTIIQLEE-KIIQVE-NKYQIQLSNESES 2778

Query: 612  RLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLE--EQID 669
              + I  +E+Q  + + EL  ++   +E+  ++A +  +   Q   + + ++ +  ++  
Sbjct: 2779 HKQLIIEIETQNKEKIAELQRIE---NELRIQIASLLGMDEKQKVDQQQKINQQGADKEQ 2835

Query: 670  ALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKL-QNYIQENMDLTDKLEKMS 728
             +   +KE+  +    +L  ++    I+D++  +    ++L Q Y+   ++ +++L K S
Sbjct: 2836 QIVILQKEIHTIESTYQLRIQEFEKQIQDIQLRESQRYSQLAQRYLLICLE-SERL-KSS 2893

Query: 729  AEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVM 788
            A + +        + QS+I     ++ +IQ     I  ++ EL+   + I +  + I + 
Sbjct: 2894 ANERNSSSGSNTSQYQSRINE---LEIQIQNHIEVISKLQQELNISSTTINQQIQKIQIY 2950

Query: 789  EDRRYSLERKADQ--LGSYL-----QEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQL 841
            E +  S     DQ  L  YL      E+ +  +     +   V+   V  D D+ + K  
Sbjct: 2951 EQQIQS-NNFTDQNLLQKYLIVCLEAERLRQVALNQSSKSMAVSNQPVDFDKDQQISK-- 3007

Query: 842  LEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKAN-RTDLAESESTKYQTQL 900
            L+I+ +  E  K +++L+  N   ++ +S ++   N  +EK +      +S+ T+     
Sbjct: 3008 LQIQVQQYE-HKMSELLITINSKQEL-ISKLETEINIHIEKVSILNQQMQSQQTQSSVDT 3065

Query: 901  RDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQL 960
            + L+  L  +  E + L +QK      ++  FN   E  I  ++V+  + E+ + Y +Q+
Sbjct: 3066 QLLQKYLI-VCLEAERLKLQKGTSGISIQQNFNDS-EIEILKQRVI--QLEQEVIYKSQI 3121

Query: 961  EAQLQEYKNNIENLNMNV-EELNK------MNLELIDKHVQKQQTQSPDYTEQYINEINK 1013
             ++ +E K    +   +  +EL++      M  E + + +QKQ+    +   + I +  +
Sbjct: 3122 ISEFEESKGVKRSTKSSQNQELSQQYLVVCMEAERLQQQLQKQKADYENQISELIKKDKR 3181

Query: 1014 LNALLKQKDEEIIALNQKI-NNAQVSYMSMVS-----DYESKLAQFTTKLENMEEEMQRV 1067
                LK  D +I ALN+K+ +++Q S  S  S     D ++K+ +   KLE  + +MQ  
Sbjct: 3182 NQEYLKINDAQIKALNEKLKSSSQSSLKSNPSSPVNEDQDNKIKEIQAKLE--KAQMQIE 3239

Query: 1068 SKQLLDSKQHNEELQILVREQDDQ--IKELKETKLTFEMNIPKTEGMII--SSTIEPMSD 1123
            S+     K HNE++ +     +    I +LK+ K + E  + + E   I  S  IE +  
Sbjct: 3240 SQMQKIEKLHNEKINVEDSNANLNRFINDLKDQKSSIEKQLHQLEKENIEKSHQIEKLEQ 3299

Query: 1124 DANNVDXXXXXXXXXXXXLKVQ--EEEEFIQERSVLQEQSAKLN---TELQECYTKIIQL 1178
            +   +             +++Q  +EEE+  +  V+  +   L    T+L+    K +  
Sbjct: 3300 EKILLQKSVEELGEKLIKMQIQQRDEEEYDDQVFVVNRKMDALKSLVTQLERDVKKYV-- 3357

Query: 1179 ETLNT-ELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAE 1237
            ET  T +  G  + + ++   L++ +EQL T+N N      ++   +   +D +  ++ +
Sbjct: 3358 ETSQTMQRIGISLFSVDRDLPLETFVEQL-TQNVN------DVLKFLEQQIDDKDAQLED 3410

Query: 1238 LWKQHLAQREADFQ-KTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQ 1296
            L +   A+ +  +Q +  H+       F++  ++ ++ V             +EQ    Q
Sbjct: 3411 LQRNLQAKDDQIYQLQNNHQQSFLQKEFQTGEDKNMEKVNEILGLSAIGADIVEQKKD-Q 3469

Query: 1297 NKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTEN 1356
            + L D +     +++K   V  QI    ++   E+ +                 + +++N
Sbjct: 3470 SFLSDHDIENIAIEDKKISV--QISYRDNDEIQERNSKMGGRPSSNQGSVQHSYNQQSQN 3527

Query: 1357 QS--------YKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQ 1408
            QS         K+  +  I ++NE++  +K+              + N +    L++ + 
Sbjct: 3528 QSSVPNVDKNIKEQYDHQIQSLNEQHRSIKRK--YDNLLIENEDLKRNLSSFYSLQVNNP 3585

Query: 1409 LELKDSEIY-QKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMH 1467
            L   +  +  Q+  +  + L Q  +E E+  +    Y+++I  L  +K  EL   +LK  
Sbjct: 3586 LNPAEINLMRQEMDQQKMQLDQLKEEIEDHEENEERYQQQIGQLK-KKIFELE-KQLKES 3643

Query: 1468 ENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALE 1527
               + Y+ + K+S     KL  + N K  E +   + +  L   L   + +  + +  L 
Sbjct: 3644 VAGHQYQAV-KDSFQNFFKLHFDKNSKTNEFIKAEEYLKILLNLL--NIGEQQKKECVLV 3700

Query: 1528 NQEI 1531
             Q++
Sbjct: 3701 YQQV 3704



 Score =  114 bits (274), Expect = 2e-23
 Identities = 219/1161 (18%), Positives = 490/1161 (42%), Gaps = 101/1161 (8%)

Query: 455  EHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNV-----KDLIEKLKSAE 509
            +HQQ    PS     T+ E + +  ++ E+   +  +++K++ V     +  I++LKS +
Sbjct: 215  KHQQQRIAPSQ-EQQTSLEVMKQEHELLEKKYSKKQNQVKELIVLVTQKEKEIKQLKSQQ 273

Query: 510  EQITQLNDEIDAANKNMIKVKSNHKLK--LKQMQKTIDNFSKVSDS----NKEIVRLTEE 563
            + I Q  +++ + N    K   NH     +   QK  D    +        +++ R + E
Sbjct: 274  QSIQQNKNQLISGNDE--KQNQNHAFGNCVLNDQKLFDYCLFLEGQYRRLERKVKRKSRE 331

Query: 564  LHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYK---KMIEMENLAETR-LKAISL- 618
            +  L ++V     +K + ++  + ++     E D YK     +   N++ ++ L  +S  
Sbjct: 332  IEILRKEVKPAVYQKIHQEIQNMKFEE---CEED-YKWNIPTLSQNNISSSKELYTLSKQ 387

Query: 619  LESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKEL 678
            +  ++ +  +EL    ++ +++ +K  +I   + ++     K    + QI      KKE+
Sbjct: 388  MMQEQSENFKELRKKLKEQEKIINKEQEIIVKEMERNLKNSKDEQKKYQIQ-YENKKKEI 446

Query: 679  ALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNY-IQENMDLTDKLE-KMSAEKISELL 736
              + ++L +    L   +  L+++   +  ++QN  I    +L +  E K+  E     L
Sbjct: 447  IQIKQSLTIQINTLSQQVDSLKSENSLLKQEIQNININRQAELNEFEEVKLQLENAEHQL 506

Query: 737  AKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLE 796
             +I  E Q+KI+       ++ E+          +S+   +I RL +  A +   +  + 
Sbjct: 507  FQIQREYQTKIE-------EVSEKKYENSQNHITVSQLNDQINRLNQENANLLKEKEQVL 559

Query: 797  RKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQ 856
            RK++     ++E Q   S+  + E +   +L +     ++ +K+  EI  + +E+ +  Q
Sbjct: 560  RKSESDKMRIEEFQLKLSK--VNEVQEQYQLEIRQLSVKLADKEN-EIYEKMQEIDQLRQ 616

Query: 857  ILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQT 916
            I    + +L+I    +++    L+++ N+   A+     +  Q+ D    L++ +  +  
Sbjct: 617  I---SSNDLEIQ--QLKEENQNLIDQINQLHEAQQTLAIHNVQINDELRRLQQQSSVNVQ 671

Query: 917  LIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNM 976
             I+ +K +I+    E  T I   I +K ++  +YE+  +   Q +A++  +   +ENL  
Sbjct: 672  QIIIEKTQIQ----ERYTYILKEIEEKNIIIHQYEEKED---QYQAEVMNFTKQLENLQE 724

Query: 977  NVEELNKMNLELIDKH----VQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALN-QK 1031
              + +N+   +L+++     +Q Q  Q+    EQ IN+   L+ + K K ++I   N +K
Sbjct: 725  KYDRMNEEFDDLLNEKEQFLIQIQDLQNKCQHEQEINQ-KYLDQIGKYKQDDIDQQNREK 783

Query: 1032 INNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQ 1091
                ++  +    D  SK ++      N E +    S Q  + K   E  QIL   Q+ Q
Sbjct: 784  KYLKEIQKLKDDIDQLSKQSKKNQHENNEEIKAMLTSLQTKNEKLEQENAQILQSSQEQQ 843

Query: 1092 IKELKETKLTFEMNIPKTEGM-IISSTIEPMSDDANNVDXXXXXXXXXXXX-LKVQEEEE 1149
             + L   ++  + NI     + I+   +         ++             L + EEE 
Sbjct: 844  NQLLTNLEMLTQQNIDVQNNLAILEEEVNQKDLKIQQLEQELQLSAQKIETFLSLAEEEN 903

Query: 1150 FI---QERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQL 1206
             I   Q +++L++Q  KL   + +   KI   + LN ++      N+E   +L+   E  
Sbjct: 904  KIKHAQNQALLKQQEQKLEIIIDDLKNKI---DKLNQQIKDQQYENKEVKFELEKCRESK 960

Query: 1207 NTENDNLLSTV---AELRSSISSAVDQRGFEIAELWKQHLAQREADF---QKTEHELRVQ 1260
              + + L        EL+  I+        +I++L +Q ++Q E      QK E +L+ +
Sbjct: 961  KEQEEKLQKQKDKNKELKQKITEIEALSVKQISQL-QQQISQYEIQIKNSQKVEQDLKDK 1019

Query: 1261 LSAFESKYEQ----LLDSVQSSTQEETNKIVT-----------MEQVTSLQNKLQDKEEH 1305
            ++  + K  Q    L    + S+   ++K V              Q+  L+N L DKE  
Sbjct: 1020 ITEIKEKLSQNQLELSKQKEKSSSSSSSKNVLRSEYIQEIEKYQNQIKELKNNLDDKERE 1079

Query: 1306 LRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQ 1365
             R +  +Y +  N+I   ++E  + +                      T +Q  +++Q++
Sbjct: 1080 TRKILTEYNEARNKILSYQTEQLENEEKIDKLKEELKVKSNKLNQQQETIDQLQQEIQKK 1139

Query: 1366 SILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTI 1425
              + ++  N  L  S              +N+       + +   +  S++ Q+ ++   
Sbjct: 1140 QNIIMSGSN-NLNNSQISQINGNSNQRRSLNNIIVDESGINNTNHV--SQLNQQINDLQN 1196

Query: 1426 TLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERV 1485
             L +R    EN+   L E  K+I+D  + ++ E      K+++  N Y+ ++ + + ER 
Sbjct: 1197 LLQER----ENIINNLKEENKQIQDFYHSEQQE------KVNQLENQYQQIENQIK-ERD 1245

Query: 1486 KLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQN 1545
              I   + ++ +    +K++ +LN  +++  +  +++       +   + L+D+   L  
Sbjct: 1246 DKIAYQSSQLDQK---SKEIQQLNDRIKQITSTKDQITQQYSKLQENNLKLHDQNVELTA 1302

Query: 1546 MVRASSSKIQKHVSFASDTKQ 1566
             +     + QK +    + +Q
Sbjct: 1303 KLENFQQEFQKIIVKVKEQEQ 1323



 Score =  101 bits (243), Expect = 1e-19
 Identities = 250/1366 (18%), Positives = 576/1366 (42%), Gaps = 130/1366 (9%)

Query: 143  DVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXX 202
            D+  L+  ++        LQ++++ ++ T  +L+E++NE   +    +K+          
Sbjct: 2165 DIEKLNENVRNSKKNSQDLQLQLQSLQQTRHNLEEQLNE---LRTLNSKSANQQSQQFSQ 2221

Query: 203  XXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLK-DIESKDVRISSLEEANKLLE 261
                     ++ +Q+  + ++     E+E     +++ K + + KD +    E  N L+E
Sbjct: 2222 LQDEYSELQQNLQQKNLQFKQMLNEHESEKSQLNEKITKIEKQLKDNQTICQEHQN-LIE 2280

Query: 262  AARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQ--SIEPSCEE-KTEIEEKGSLEI 318
                +I  +  K+ +   Q                K+  +++   E+ K  IE       
Sbjct: 2281 QNNLKIKEQQQKIKEYENQISQMQQQNEEQAKIQQKEQNNLDKEIEKLKKHIESNQKEAA 2340

Query: 319  ANMTELTKK----IELLE-----HLNCQIRQTNKELENKLATMGTESKAVSSPSKKGS-- 367
                EL KK    I+ ++     HL  Q+ Q  ++ E ++  +  + K  +    + S  
Sbjct: 2341 EQQQELIKKHQQEIDNIQNQNDIHLQQQLNQLKQQYEVQIQQITKQQKEEAQKHNQSSEQ 2400

Query: 368  --PLISRKSGRNTASKMKSPWSQLSS-ETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDK 424
                I+ K  ++  + ++    +++     N+   +K + N+I K+  + Q    +  + 
Sbjct: 2401 QIQQITAKYQQDIQNIVQQNEQKIAELNEANKQLSQKDSDNQI-KIHQLQQESENNSTNF 2459

Query: 425  EYVISEK----DTXXXXXXXXXXGKDTLIAQ---LQLEHQQHMEGPSLIHVGTNTEDVNE 477
            E  ISE     +            K T I Q   +Q+   +      +  +  + +  NE
Sbjct: 2460 ETKISENSKIYEEKISQISITFETKITEIKQSYEIQINELKQQYETKIQSLQESEKQTNE 2519

Query: 478  IAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKL 537
             +  +   KQEL  ++K+   K++ EK ++  +Q+ ++ D +D   K +   +S  K   
Sbjct: 2520 SSNKE---KQELISKLKEEFQKEIAEKDENHNKQVKEIQDNLD---KQINDYESKIKALQ 2573

Query: 538  KQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESD 597
               QK I+  SK +D  K I  +TE+     +++++L E +        D +  ++    
Sbjct: 2574 VDYQKQIEE-SK-ADHEKNIKEITEK---FEKQISDLNERQQK------DIEGIQINHEF 2622

Query: 598  VYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCS 657
            + K   E++   ET    +  +  +K D+V +        +E E ++ +I Q    Q+  
Sbjct: 2623 IIK---ELQKKIETLTITLDEINQEKEDIVNKAK------EEAEQEIQNIDQKYRSQI-Q 2672

Query: 658  EIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQEN 717
            ++   H +  ++  S  +  +  V E  +L+ ++L   I    +D  +++ K  N I+E 
Sbjct: 2673 QMHKDHNDYILNTESDQQDAIQTVKEQYELEIQELKQMI---PSDSNELIQKYLNQIKE- 2728

Query: 718  MDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAK-IQERDLYIENIESELSKYKS 776
              L +K++++  +       + N E Q    T   ++ K IQ  + Y   + +E   +K 
Sbjct: 2729 --LEEKIQQLQQQD-----TQSNEENQRLELTIIQLEEKIIQVENKYQIQLSNESESHKQ 2781

Query: 777  RICRLE----ESIAVMEDRRYSLE-RKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLM 831
             I  +E    E IA ++     L  + A  LG  + EKQK      + + + +N+     
Sbjct: 2782 LIIEIETQNKEKIAELQRIENELRIQIASLLG--MDEKQK------VDQQQKINQQGA-- 2831

Query: 832  DHDRVVEKQLLEIEHENKELQKKNQILLE--ENQNLQISLSDMQQHYNALVEKANRTDLA 889
              D+  E+Q++ ++ E   ++   Q+ ++  E Q   I L +  Q Y+ L   A R  L 
Sbjct: 2832 --DK--EQQIVILQKEIHTIESTYQLRIQEFEKQIQDIQLRE-SQRYSQL---AQRYLLI 2883

Query: 890  ESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIR-DKKVLNE 948
              ES + ++   +  S+    T ++Q+ I + + +I++  IE  ++++  +      +N+
Sbjct: 2884 CLESERLKSSANERNSSSGSNTSQYQSRINELEIQIQN-HIEVISKLQQELNISSTTINQ 2942

Query: 949  KYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYI 1008
            + +K   Y  Q+++     +N ++   +   E  ++    +++  +     +        
Sbjct: 2943 QIQKIQIYEQQIQSNNFTDQNLLQKYLIVCLEAERLRQVALNQSSKSMAVSNQPVDFDKD 3002

Query: 1009 NEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVS 1068
             +I+KL   ++Q + ++  L   IN+ Q     ++S  E+++     K+  + ++MQ   
Sbjct: 3003 QQISKLQIQVQQYEHKMSELLITINSKQ----ELISKLETEINIHIEKVSILNQQMQSQQ 3058

Query: 1069 KQLLDSKQHNEELQILVREQDDQIKELKETK-LTFEMNIPKTEGMIISSTIEPMSDDA-- 1125
             Q     Q  ++  I+  E  +++K  K T  ++ + N   +E  I+   +  +  +   
Sbjct: 3059 TQSSVDTQLLQKYLIVCLEA-ERLKLQKGTSGISIQQNFNDSEIEILKQRVIQLEQEVIY 3117

Query: 1126 -NNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTE 1184
             + +              K  + +E  Q+  V+  ++ +L  +LQ+   +    E   +E
Sbjct: 3118 KSQIISEFEESKGVKRSTKSSQNQELSQQYLVVCMEAERLQQQLQK---QKADYENQISE 3174

Query: 1185 LTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAV----DQRGFEIAELWK 1240
            L   D  NQE +    ++++ LN +  +  S+ + L+S+ SS V    D +  EI    +
Sbjct: 3175 LIKKDKRNQEYLKINDAQIKALNEKLKS--SSQSSLKSNPSSPVNEDQDNKIKEIQAKLE 3232

Query: 1241 QHLAQREADFQKTE--HELRVQLSAFESKYEQLLDSV---QSSTQEETNKIVTMEQVTSL 1295
            +   Q E+  QK E  H  ++ +    +   + ++ +   +SS +++ +++       S 
Sbjct: 3233 KAQMQIESQMQKIEKLHNEKINVEDSNANLNRFINDLKDQKSSIEKQLHQLEKENIEKSH 3292

Query: 1296 Q-NKLQDKEEHLRNLQEKYADVINQIEILR---SEIEDEKVAFXXXXXXXXXXXXXXXXD 1351
            Q  KL+ ++  L+   E+  + + +++I +    E +D+                    D
Sbjct: 3293 QIEKLEQEKILLQKSVEELGEKLIKMQIQQRDEEEYDDQVFVVNRKMDALKSLVTQLERD 3352

Query: 1352 LRTENQSYKQMQE--QSILNINEE---NAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELT 1406
            ++   ++ + MQ    S+ +++ +      +++ +            +++D +A++ +L 
Sbjct: 3353 VKKYVETSQTMQRIGISLFSVDRDLPLETFVEQLTQNVNDVLKFLEQQIDDKDAQLEDLQ 3412

Query: 1407 HQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLT 1452
              L+ KD +IYQ  + +  +  Q+  EF+    + +E    I  L+
Sbjct: 3413 RNLQAKDDQIYQLQNNHQQSFLQK--EFQTGEDKNMEKVNEILGLS 3456



 Score = 54.8 bits (126), Expect = 2e-05
 Identities = 79/451 (17%), Positives = 184/451 (40%), Gaps = 31/451 (6%)

Query: 1152 QERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTEND 1211
            QE  +L+++ +K   +++E    + Q E    +L       Q+  NQL S  ++   +N 
Sbjct: 236  QEHELLEKKYSKKQNQVKELIVLVTQKEKEIKQLKSQQQSIQQNKNQLISGNDEKQNQNH 295

Query: 1212 NLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFE-SKYEQ 1270
               + V           DQ+ F+     +    + E   ++   E+ +     + + Y++
Sbjct: 296  AFGNCVLN---------DQKLFDYCLFLEGQYRRLERKVKRKSREIEILRKEVKPAVYQK 346

Query: 1271 LLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDE 1330
            +   +Q+   EE  +       T  QN +   +E     ++   +     + LR +++++
Sbjct: 347  IHQEIQNMKFEECEEDYKWNIPTLSQNNISSSKELYTLSKQMMQEQSENFKELRKKLKEQ 406

Query: 1331 KVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXX 1390
            +                   + + E + Y+   E    N  +E  Q+K+S          
Sbjct: 407  EKIINKEQEIIVKEMERNLKNSKDEQKKYQIQYE----NKKKEIIQIKQS---------- 452

Query: 1391 XXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIED 1450
               ++N    +V      L+ ++S + Q+     I      +EFE V+ QL   E ++  
Sbjct: 453  LTIQINTLSQQV----DSLKSENSLLKQEIQNININRQAELNEFEEVKLQLENAEHQLFQ 508

Query: 1451 LTYEKESELAILRLKMHENA-NHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELN 1509
            +  E ++++  +  K +EN+ NH    Q   +I R+   E  N+   +   L K  ++  
Sbjct: 509  IQREYQTKIEEVSEKKYENSQNHITVSQLNDQINRLNQ-ENANLLKEKEQVLRKSESDKM 567

Query: 1510 KALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRD 1569
            + +EE   K +++    E  ++EI  L+ ++ + +N +     +I +    +S+  + + 
Sbjct: 568  R-IEEFQLKLSKVNEVQEQYQLEIRQLSVKLADKENEIYEKMQEIDQLRQISSNDLEIQQ 626

Query: 1570 EQLDNTMNKELLDAVPRAELDLAMYMLHQRD 1600
             + +N    + ++ +  A+  LA++ +   D
Sbjct: 627  LKEENQNLIDQINQLHEAQQTLAIHNVQIND 657


>UniRef50_A2EJ43 Cluster: Viral A-type inclusion protein, putative;
            n=1; Trichomonas vaginalis G3|Rep: Viral A-type inclusion
            protein, putative - Trichomonas vaginalis G3
          Length = 940

 Score =  167 bits (407), Expect = 2e-39
 Identities = 186/881 (21%), Positives = 408/881 (46%), Gaps = 68/881 (7%)

Query: 473  EDVNEIAKVQEQLKQELND--EIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVK 530
            + + E  K   +LK+EL    E K+  + +L+ +++  ++QI    DEI   N+N+ K K
Sbjct: 6    KQIEEKDKQINELKEELQKQTEEKETEINELMNQIEDLQKQI----DEIKNQNENLQKEK 61

Query: 531  SNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDS 590
             N    L +M K ID+  K  +  ++   L EE      +++EL+++  +LQ    +   
Sbjct: 62   EN---SLNEMNKQIDDLQKEKEETEKA--LIEENEDYKNQLSELKKQIEDLQNENEEKVE 116

Query: 591  GRMIESDVYKKMI-EMENLAETRLKAISLLES--QKF--DLVQELHILQQKYDEVEDKLA 645
                E++ +   I ++++  E   K++S  E   QKF  +L Q++  L+QK   V D+  
Sbjct: 117  NLKKENEEFNNEIKDLQDQIELLKKSMSESEDKDQKFVIELNQQIEKLKQK---VSDE-K 172

Query: 646  DISQLQSDQVCS-EIKSVHLEEQIDALSASKKELALVIENL--KL----DKEQLYGTIKD 698
            D+ Q++ +++   + K+  L EQ + L+  K EL   IE L  KL    +KE+L   I +
Sbjct: 173  DLIQVKDEEIIDLKQKNTDLSEQNNKLNEDKNELEKQIEELAQKLSDESEKEKLKQEINE 232

Query: 699  LENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQ 758
            L+++KE   N  +++ ++  +LT K+ ++  + IS+   +I+  E +K      +D   +
Sbjct: 233  LKSEKE---NSEKDFNKKLENLTQKVTELE-DSISQKTREIDEAETAKEDISLKLDNLAE 288

Query: 759  ERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTI 818
            E +   +N+     K   ++   E+     ED +   E       S  +E  K       
Sbjct: 289  ENEKLSQNLSEIYEKLNEKVTETEKLQKENEDLKSENELLKKDSDSAQEELMKENENLKK 348

Query: 819  QEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNA 878
            +  E+  ++  L       +K + +++ + +E+  +N    EE++  Q  + D+ Q    
Sbjct: 349  ENGEITEKIEELQKEIGERQKTVEDLKQKIEEINSQNA---EESEKNQKEIDDLTQEIEE 405

Query: 879  LVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIES 938
            + +K +       +  K +  L+     +K+   E+Q  I   +KE +DL+   N   E 
Sbjct: 406  INQKLDEKQKENDDLKKEKENLQKEVDEIKKNFEENQNQIENLQKENDDLKKGMNQSSEE 465

Query: 939  AIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQT 998
              + K++  E+ +KN E   + + ++ +     E +N  ++E  K  +E I + +++ Q 
Sbjct: 466  --KQKEI--EEIKKNFE---EKQKEIDDLTQENEEMNQKLDEKQK-EIEEIKQKIEENQK 517

Query: 999  QSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLE 1058
            Q+ D  ++  +   ++  L +QK ++     + +N+ Q +    + + +++    + +LE
Sbjct: 518  QNVDLKKEVEDLTQEIEKLEEQKSQK----EENVNSEQENLQKQIEELKNEKETISNELE 573

Query: 1059 NMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTI 1118
            +  +  +++   L +  + N EL I + E+  Q KE+    +    N    E   +   +
Sbjct: 574  SKTKHNEKLVSSLQEFAKKNAELDITI-ERLTQEKEVLINNVNDLQNNVDAEIRDLKVKL 632

Query: 1119 EPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQL 1178
            +   ++ + ++            LK Q++EE  +E    Q+++  L  E+ +   +I +L
Sbjct: 633  QEKDEEIDGLNEQIEQIIKENNDLK-QKQEENQKENEQKQKENEDLKKEVDDLTQEIEKL 691

Query: 1179 ETLNTELTGHDVVN-----QEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGF 1233
            E   ++    +V +     Q+QI +LK ++EQ   +N++L+    E+        D++  
Sbjct: 692  EEQKSQKEEENVNSEQENLQKQIEELKKEVEQYKKQNEDLIEENEEM--------DEK-M 742

Query: 1234 EIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKI-VTMEQV 1292
            +I +   + + +   +  +  + L+  L   E + E+++   +    +E +++   +E+ 
Sbjct: 743  KILQKQIEEIKETNEESSEQIYALKKDLEIAEQEKERIVKMEREQNMKEISQLKFEVEEK 802

Query: 1293 TSL----QNKLQDKEEHLRNLQEK-YADVINQIEILRSEIE 1328
              +    QNK Q   E  +  ++K  A+V  +  + +S I+
Sbjct: 803  RRISEEYQNKCQSIAEEFKQREKKVLAEVEKKFNMFKSAID 843



 Score =  145 bits (352), Expect = 8e-33
 Identities = 176/834 (21%), Positives = 373/834 (44%), Gaps = 70/834 (8%)

Query: 788  MEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHE 847
            M + +  +E K  Q+    +E QK   E   + +EL+N++  L       +KQ+ EI+++
Sbjct: 1    MNEIKKQIEEKDKQINELKEELQKQTEEKETEINELMNQIEDL-------QKQIDEIKNQ 53

Query: 848  NKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNL 907
            N+ LQK+ +  L E  N QI   D+Q+      EKA    L E E+  Y+ QL +L+  +
Sbjct: 54   NENLQKEKENSLNE-MNKQID--DLQKEKEE-TEKA----LIE-ENEDYKNQLSELKKQI 104

Query: 908  KRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEY 967
            + + +E++  +   KKE E+   E     +     KK ++E  +K+ ++V +L  Q+++ 
Sbjct: 105  EDLQNENEEKVENLKKENEEFNNEIKDLQDQIELLKKSMSESEDKDQKFVIELNQQIEKL 164

Query: 968  KNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQK---DEE 1024
            K  + +    ++  ++  ++L  K+    + Q+    E   NE+ K    L QK   + E
Sbjct: 165  KQKVSDEKDLIQVKDEEIIDLKQKNTDLSE-QNNKLNEDK-NELEKQIEELAQKLSDESE 222

Query: 1025 IIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQIL 1084
               L Q+IN  +    +   D+  KL   T K+  +E+ + + ++++ +++   E++ + 
Sbjct: 223  KEKLKQEINELKSEKENSEKDFNKKLENLTQKVTELEDSISQKTREIDEAETAKEDISLK 282

Query: 1085 VREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKV 1144
            +    ++ ++L +     E+     E +  +  ++  ++D  + +              +
Sbjct: 283  LDNLAEENEKLSQN--LSEIYEKLNEKVTETEKLQKENEDLKSENELLKKDSDSAQEELM 340

Query: 1145 QEEEEFIQERSVLQEQSAKLNTELQECYTKIIQL----ETLNTELTGHDVVNQEQINQLK 1200
            +E E   +E   + E+  +L  E+ E    +  L    E +N++       NQ++I+ L 
Sbjct: 341  KENENLKKENGEITEKIEELQKEIGERQKTVEDLKQKIEEINSQNAEESEKNQKEIDDLT 400

Query: 1201 SKLEQLNTENDNLLSTVAELRS---SISSAVDQ--RGFEIAELWKQHLAQREADFQK--- 1252
             ++E++N + D       +L+    ++   VD+  + FE  +   ++L +   D +K   
Sbjct: 401  QEIEEINQKLDEKQKENDDLKKEKENLQKEVDEIKKNFEENQNQIENLQKENDDLKKGMN 460

Query: 1253 -TEHELRVQLSAFESKYEQLLDSVQSSTQE--ETNKIVTMEQ--VTSLQNKLQDKEEHLR 1307
             +  E + ++   +  +E+    +   TQE  E N+ +  +Q  +  ++ K+++ ++   
Sbjct: 461  QSSEEKQKEIEEIKKNFEEKQKEIDDLTQENEEMNQKLDEKQKEIEEIKQKIEENQKQNV 520

Query: 1308 NLQEKYADVINQIEIL---RSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQE 1364
            +L+++  D+  +IE L   +S+ E+   +                  +  E +S  +  E
Sbjct: 521  DLKKEVEDLTQEIEKLEEQKSQKEENVNSEQENLQKQIEELKNEKETISNELESKTKHNE 580

Query: 1365 QSILNINE---ENAQLKKSSXXXXXXXXXXXXRVND----AEAKVLELTHQLELKDSEIY 1417
            + + ++ E   +NA+L  +              VND     +A++ +L  +L+ KD EI 
Sbjct: 581  KLVSSLQEFAKKNAELDITIERLTQEKEVLINNVNDLQNNVDAEIRDLKVKLQEKDEEID 640

Query: 1418 QKTHEYTITLTQRND----------EFENVRQQLVEYEKRIEDLTYEKESELAILRLKMH 1467
                +    + + ND          E E  +++  + +K ++DLT E E        K  
Sbjct: 641  GLNEQIEQIIKENNDLKQKQEENQKENEQKQKENEDLKKEVDDLTQEIEKLEEQKSQKEE 700

Query: 1468 ENAN-HYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALE---EEVAKTNE-- 1521
            EN N   E +QK+ E E  K +E+   +  + +  N+++ E  K L+   EE+ +TNE  
Sbjct: 701  ENVNSEQENLQKQIE-ELKKEVEQYKKQNEDLIEENEEMDEKMKILQKQIEEIKETNEES 759

Query: 1522 -MQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDN 1574
              Q     +++EI     E   +  M R  + K    + F  + K+   E+  N
Sbjct: 760  SEQIYALKKDLEIA--EQEKERIVKMEREQNMKEISQLKFEVEEKRRISEEYQN 811



 Score =  145 bits (351), Expect = 1e-32
 Identities = 206/968 (21%), Positives = 435/968 (44%), Gaps = 98/968 (10%)

Query: 151  IKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXX 210
            I E  N +  LQ ++  ++    +LQ+   EK+  +   NK                   
Sbjct: 33   INELMNQIEDLQKQIDEIKNQNENLQK---EKENSLNEMNKQIDDLQKEKEETEKALIEE 89

Query: 211  XEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLE 270
             ED K Q++++++    ++ E +++ + L K+ E  +  I  L++  +LL+ +  E   +
Sbjct: 90   NEDYKNQLSELKKQIEDLQNENEEKVENLKKENEEFNNEIKDLQDQIELLKKSMSESEDK 149

Query: 271  HSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEK---TEIEEKGSLEIANMTELTKK 327
              K   EL Q              L +   E   + K   T++ E+ +    +  EL K+
Sbjct: 150  DQKFVIELNQQIEKLKQKVSDEKDLIQVKDEEIIDLKQKNTDLSEQNNKLNEDKNELEKQ 209

Query: 328  IELL----------EHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRN 377
            IE L          E L  +I +   E EN       + + ++    +    IS+K+   
Sbjct: 210  IEELAQKLSDESEKEKLKQEINELKSEKENSEKDFNKKLENLTQKVTELEDSISQKTREI 269

Query: 378  TASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXX 437
              ++       L  + L ++ +K +++N    L  + + LN+ + + E +  E +     
Sbjct: 270  DEAETAKEDISLKLDNLAEENEK-LSQN----LSEIYEKLNEKVTETEKLQKENEDLKSE 324

Query: 438  XXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAK-VQEQLK--QELNDEIK 494
                    D+   +L  E++   +       G  TE + E+ K + E+ K  ++L  +I+
Sbjct: 325  NELLKKDSDSAQEELMKENENLKK-----ENGEITEKIEELQKEIGERQKTVEDLKQKIE 379

Query: 495  DVNVKDLIEKLKSAEEQITQLNDEIDAANKNMI-KVKSNHKLKLKQ--MQKTIDNFSKVS 551
            ++N ++  E  K+ +E I  L  EI+  N+ +  K K N  LK ++  +QK +D   K  
Sbjct: 380  EINSQNAEESEKNQKE-IDDLTQEIEEINQKLDEKQKENDDLKKEKENLQKEVDEIKKNF 438

Query: 552  DSNK-EIVRLTEELHHLSQKVAELEEEKGN-LQLHLVDYDSGRMIESDVYKKMIEMENLA 609
            + N+ +I  L +E   L + + +  EEK   ++    +++  +    D+ ++  EM    
Sbjct: 439  EENQNQIENLQKENDDLKKGMNQSSEEKQKEIEEIKKNFEEKQKEIDDLTQENEEMNQKL 498

Query: 610  ETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQID 669
            + + K I  ++ QK +  Q+ ++  +K  EVED   +I +L+      E KS   EE ++
Sbjct: 499  DEKQKEIEEIK-QKIEENQKQNVDLKK--EVEDLTQEIEKLE------EQKS-QKEENVN 548

Query: 670  ALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSA 729
            +    ++ L   IE LK +KE +   ++      E +++ LQ + ++N +L   +E+++ 
Sbjct: 549  S---EQENLQKQIEELKNEKETISNELESKTKHNEKLVSSLQEFAKKNAELDITIERLTQ 605

Query: 730  EKISELLAKINHEEQSKIQTQF-GIDAKIQERDLYI----ENIESELSKYKSRICRLEES 784
            EK  E+L    ++ Q+ +  +   +  K+QE+D  I    E IE  + +      + EE+
Sbjct: 606  EK--EVLINNVNDLQNNVDAEIRDLKVKLQEKDEEIDGLNEQIEQIIKENNDLKQKQEEN 663

Query: 785  IAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEI 844
                E ++   E    ++    QE +K   + + +E+E VN           ++KQ+ E+
Sbjct: 664  QKENEQKQKENEDLKKEVDDLTQEIEKLEEQKSQKEEENVN------SEQENLQKQIEEL 717

Query: 845  EHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLE 904
            + E ++ +K+N+ L+EEN+ +   +  +Q+     +E+   T+  E  S +     +DLE
Sbjct: 718  KKEVEQYKKQNEDLIEENEEMDEKMKILQKQ----IEEIKETN--EESSEQIYALKKDLE 771

Query: 905  SNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQL 964
                 I  + +  IV+ ++E    EI   +Q++  + +K+ ++E+Y+   + + +     
Sbjct: 772  -----IAEQEKERIVKMEREQNMKEI---SQLKFEVEEKRRISEEYQNKCQSIAE----- 818

Query: 965  QEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEE 1024
             E+K   + +   VE+   M    IDK V K Q           N++N + A+ K   E 
Sbjct: 819  -EFKQREKKVLAEVEKKFNMFKSAIDKIVSKLQIVD--------NKLNNIKAIEKTVIES 869

Query: 1025 IIALNQKINNAQVSY-MSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQI 1083
            +  +   I++ ++++ +S ++    K  +  ++     E+ Q  +KQ++ +      +Q 
Sbjct: 870  LAPV-LGIDSTEINFDVSSITPLVEKAKRHISREARWREKYQN-AKQIIYA------IQT 921

Query: 1084 LVREQDDQ 1091
            +++ +D Q
Sbjct: 922  IIKSEDPQ 929



 Score =  141 bits (341), Expect = 2e-31
 Identities = 179/891 (20%), Positives = 397/891 (44%), Gaps = 56/891 (6%)

Query: 675  KKELALVIENLKLDKEQLYGTIKDLENDKEDIMNK---LQNYIQENMDLTDKLEKMSAEK 731
            KK++    + +   KE+L    ++ E +  ++MN+   LQ  I E  +  + L+K     
Sbjct: 5    KKQIEEKDKQINELKEELQKQTEEKETEINELMNQIEDLQKQIDEIKNQNENLQKEKENS 64

Query: 732  ISELLAKINHEEQSKIQTQFGI-----DAKIQERDL--YIENIESE-LSKYKSRICRLEE 783
            ++E+  +I+  ++ K +T+  +     D K Q  +L   IE++++E   K ++     EE
Sbjct: 65   LNEMNKQIDDLQKEKEETEKALIEENEDYKNQLSELKKQIEDLQNENEEKVENLKKENEE 124

Query: 784  SIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLE 843
                ++D +  +E     +     + QK   E   Q ++L  +++   D  +V ++++++
Sbjct: 125  FNNEIKDLQDQIELLKKSMSESEDKDQKFVIELNQQIEKLKQKVSDEKDLIQVKDEEIID 184

Query: 844  IEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKAN-RTDLAESESTKYQTQLRD 902
            ++ +N +L ++N  L E+   L+  + ++ Q  +   EK   + ++ E +S K  ++ +D
Sbjct: 185  LKQKNTDLSEQNNKLNEDKNELEKQIEELAQKLSDESEKEKLKQEINELKSEKENSE-KD 243

Query: 903  LESNLKRITH---EHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQ 959
                L+ +T    E +  I QK +EI++ E    T  E        L E+ EK  + +++
Sbjct: 244  FNKKLENLTQKVTELEDSISQKTREIDEAE----TAKEDISLKLDNLAEENEKLSQNLSE 299

Query: 960  LEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLK 1019
            +  +L E     E L    E+L   N EL+ K     Q +     E    E  ++   ++
Sbjct: 300  IYEKLNEKVTETEKLQKENEDLKSEN-ELLKKDSDSAQEELMKENENLKKENGEITEKIE 358

Query: 1020 QKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNE 1079
            +  +EI    + + + +     + S    +  +   +++++ +E++ ++++L + ++ N+
Sbjct: 359  ELQKEIGERQKTVEDLKQKIEEINSQNAEESEKNQKEIDDLTQEIEEINQKLDEKQKEND 418

Query: 1080 ELQILVREQDDQIKELKETKLTFEMNIPKTEGM-IISSTIEPMSDDANNVDXXXXXXXXX 1138
            +L+   +E+++  KE+ E K  FE N  + E +   +  ++   + ++            
Sbjct: 419  DLK---KEKENLQKEVDEIKKNFEENQNQIENLQKENDDLKKGMNQSSEEKQKEIEEIKK 475

Query: 1139 XXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTG--HDVVNQ-EQ 1195
                K +E ++  QE   + ++  +   E++E   KI + +  N +L     D+  + E+
Sbjct: 476  NFEEKQKEIDDLTQENEEMNQKLDEKQKEIEEIKQKIEENQKQNVDLKKEVEDLTQEIEK 535

Query: 1196 INQLKS-KLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTE 1254
            + + KS K E +N+E +NL   + EL++   +  ++   E      + L     +F K  
Sbjct: 536  LEEQKSQKEENVNSEQENLQKQIEELKNEKETISNE--LESKTKHNEKLVSSLQEFAKKN 593

Query: 1255 HELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYA 1314
             EL + +     + E L+++V +  Q   +      ++  L+ KLQ+K+E +  L E+  
Sbjct: 594  AELDITIERLTQEKEVLINNV-NDLQNNVD-----AEIRDLKVKLQEKDEEIDGLNEQIE 647

Query: 1315 DVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQ-SILNINEE 1373
             +I +   L+ + ++E                    DL  E +  ++ + Q    N+N E
Sbjct: 648  QIIKENNDLKQK-QEENQKENEQKQKENEDLKKEVDDLTQEIEKLEEQKSQKEEENVNSE 706

Query: 1374 NAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDE 1433
               L+K              +  D    ++E   +++ K  +I QK  E    + + N+E
Sbjct: 707  QENLQKQIEELKKEVEQYKKQNED----LIEENEEMDEK-MKILQKQIE---EIKETNEE 758

Query: 1434 FENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNV 1493
                 +Q+   +K +E    EKE       +KM    N  E  Q + E+E  + I E   
Sbjct: 759  SS---EQIYALKKDLEIAEQEKER-----IVKMEREQNMKEISQLKFEVEEKRRISEEYQ 810

Query: 1494 KITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQ 1544
               +S++   +  E  K L E   K N  ++A++    ++  +++++ N++
Sbjct: 811  NKCQSIAEEFKQRE-KKVLAEVEKKFNMFKSAIDKIVSKLQIVDNKLNNIK 860



 Score =  123 bits (297), Expect = 4e-26
 Identities = 141/674 (20%), Positives = 302/674 (44%), Gaps = 43/674 (6%)

Query: 922  KKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVE-E 980
            KK+IE+ + + N   E   +  +    +  + +  +  L+ Q+ E KN  ENL    E  
Sbjct: 5    KKQIEEKDKQINELKEELQKQTEEKETEINELMNQIEDLQKQIDEIKNQNENLQKEKENS 64

Query: 981  LNKMNLELIDKHVQKQQTQSP--DYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVS 1038
            LN+MN ++ D   +K++T+    +  E Y N++++L   ++    E     +K+ N +  
Sbjct: 65   LNEMNKQIDDLQKEKEETEKALIEENEDYKNQLSELKKQIEDLQNE---NEEKVENLKKE 121

Query: 1039 YMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKET 1098
                 ++ +    Q     ++M E   +  K +++  Q  E+L+  V ++ D I ++K+ 
Sbjct: 122  NEEFNNEIKDLQDQIELLKKSMSESEDKDQKFVIELNQQIEKLKQKVSDEKDLI-QVKDE 180

Query: 1099 KLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQ 1158
            ++  ++    T+   +S     +++D N ++            L  + E+E +++  + +
Sbjct: 181  EI-IDLKQKNTD---LSEQNNKLNEDKNELE---KQIEELAQKLSDESEKEKLKQ-EINE 232

Query: 1159 EQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVA 1218
             +S K N+E ++   K+  L    TEL         +I++ ++  E ++ + DNL     
Sbjct: 233  LKSEKENSE-KDFNKKLENLTQKVTELEDSISQKTREIDEAETAKEDISLKLDNLAEENE 291

Query: 1219 ELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSS 1278
            +L  ++S   ++   ++ E  K    Q+E +  K+E+EL  + S  +S  E+L+     +
Sbjct: 292  KLSQNLSEIYEKLNEKVTETEK---LQKENEDLKSENELLKKDS--DSAQEELMKE-NEN 345

Query: 1279 TQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQ--IEILRSEIE-DEKVAFX 1335
             ++E  +I   E++  LQ ++ ++++ + +L++K  ++ +Q   E  +++ E D+     
Sbjct: 346  LKKENGEIT--EKIEELQKEIGERQKTVEDLKQKIEEINSQNAEESEKNQKEIDDLTQEI 403

Query: 1336 XXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRV 1395
                           DL+ E ++ ++  ++   N  E   Q++                 
Sbjct: 404  EEINQKLDEKQKENDDLKKEKENLQKEVDEIKKNFEENQNQIENLQKENDDLKKGMNQSS 463

Query: 1396 NDAEAKVLELTHQLELKDSEI---YQKTHEYTITLTQRNDEFENVRQQL-------VEYE 1445
             + + ++ E+    E K  EI    Q+  E    L ++  E E ++Q++       V+ +
Sbjct: 464  EEKQKEIEEIKKNFEEKQKEIDDLTQENEEMNQKLDEKQKEIEEIKQKIEENQKQNVDLK 523

Query: 1446 KRIEDLTYEKESELAILRLKMHENAN-HYETMQKESEIERVKLIEELNVKITESVSLNKQ 1504
            K +EDLT E E +L   + +  EN N   E +QK  +IE +K   E      E  S  K 
Sbjct: 524  KEVEDLTQEIE-KLEEQKSQKEENVNSEQENLQK--QIEELK--NEKETISNELESKTKH 578

Query: 1505 VAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDT 1564
              +L  +L+E   K  E+   +E    E   L + + +LQN V A    ++  +    + 
Sbjct: 579  NEKLVSSLQEFAKKNAELDITIERLTQEKEVLINNVNDLQNNVDAEIRDLKVKLQEKDEE 638

Query: 1565 KQGRDEQLDNTMNK 1578
              G +EQ++  + +
Sbjct: 639  IDGLNEQIEQIIKE 652



 Score =  114 bits (274), Expect = 2e-23
 Identities = 127/592 (21%), Positives = 261/592 (44%), Gaps = 53/592 (8%)

Query: 1014 LNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLD 1073
            +N + KQ +E+    +++IN  +        + E+++ +   ++E++++++  +  Q  +
Sbjct: 1    MNEIKKQIEEK----DKQINELKEELQKQTEEKETEINELMNQIEDLQKQIDEIKNQNEN 56

Query: 1074 -SKQHNEELQILVREQDDQIKELKET-KLTFEMNIP-KTEGMIISSTIEPM-SDDANNVD 1129
              K+    L  + ++ DD  KE +ET K   E N   K +   +   IE + +++   V+
Sbjct: 57   LQKEKENSLNEMNKQIDDLQKEKEETEKALIEENEDYKNQLSELKKQIEDLQNENEEKVE 116

Query: 1130 XXXXXXXXXXXXLK-VQEEEEFIQER-SVLQEQSAKLNTELQECYTKIIQLETLNTELTG 1187
                        +K +Q++ E +++  S  +++  K   EL +   K+ Q  +   +L  
Sbjct: 117  NLKKENEEFNNEIKDLQDQIELLKKSMSESEDKDQKFVIELNQQIEKLKQKVSDEKDLIQ 176

Query: 1188 HDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIA-ELWKQHLAQR 1246
               V  E+I  LK K   L+ +N+ L     EL   I     +   E   E  KQ + + 
Sbjct: 177  ---VKDEEIIDLKQKNTDLSEQNNKLNEDKNELEKQIEELAQKLSDESEKEKLKQEINEL 233

Query: 1247 EADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVT-SLQNKLQDKEEH 1305
            +++ + +E +   +L     K  +L DS+   T+E        E ++  L N  ++ E+ 
Sbjct: 234  KSEKENSEKDFNKKLENLTQKVTELEDSISQKTREIDEAETAKEDISLKLDNLAEENEKL 293

Query: 1306 LRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQ 1365
             +NL E Y  +  ++       E EK+                  DL++EN+  K+  + 
Sbjct: 294  SQNLSEIYEKLNEKVT------ETEKLQ-------------KENEDLKSENELLKKDSDS 334

Query: 1366 SILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTI 1425
            +   + +EN  LKK +             + + +  V +L  ++E  +S+  +++ +   
Sbjct: 335  AQEELMKENENLKKENGEITEKIEELQKEIGERQKTVEDLKQKIEEINSQNAEESEKNQK 394

Query: 1426 TLTQRNDEFENVRQQLVEYEKRIEDLTYEKES---ELAILRLKMHENANHYETMQKE--- 1479
             +     E E + Q+L E +K  +DL  EKE+   E+  ++    EN N  E +QKE   
Sbjct: 395  EIDDLTQEIEEINQKLDEKQKENDDLKKEKENLQKEVDEIKKNFEENQNQIENLQKENDD 454

Query: 1480 -------SEIERVKLIEELNVKITESV----SLNKQVAELNKALEEEVAKTNEMQTALEN 1528
                   S  E+ K IEE+     E       L ++  E+N+ L+E+  +  E++  +E 
Sbjct: 455  LKKGMNQSSEEKQKEIEEIKKNFEEKQKEIDDLTQENEEMNQKLDEKQKEIEEIKQKIEE 514

Query: 1529 QEIEIVTLNDEITNL-QNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKE 1579
             + + V L  E+ +L Q + +    K QK  +  S+ ++   +Q++   N++
Sbjct: 515  NQKQNVDLKKEVEDLTQEIEKLEEQKSQKEENVNSE-QENLQKQIEELKNEK 565



 Score = 46.8 bits (106), Expect = 0.005
 Identities = 83/425 (19%), Positives = 170/425 (40%), Gaps = 26/425 (6%)

Query: 143 DVTHLSNTIKEKDNALSVLQVK----MKIMETTILDLQEKINEKDQIIEAKNKAT---TX 195
           +V  +    +E  N +  LQ +     K M  +  + Q++I E  +  E K K     T 
Sbjct: 430 EVDEIKKNFEENQNQIENLQKENDDLKKGMNQSSEEKQKEIEEIKKNFEEKQKEIDDLTQ 489

Query: 196 XXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEE 255
                           E+ KQ++ + Q+  + ++ E +D  Q + K  E K  +  ++  
Sbjct: 490 ENEEMNQKLDEKQKEIEEIKQKIEENQKQNVDLKKEVEDLTQEIEKLEEQKSQKEENVNS 549

Query: 256 ANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGS 315
             + L+    E+  E   ++ ELE                AK++ E     +   +EK  
Sbjct: 550 EQENLQKQIEELKNEKETISNELESKTKHNEKLVSSLQEFAKKNAELDITIERLTQEKEV 609

Query: 316 LEIANMTELTKKIEL-LEHLNCQIRQTNKE---LENKLATMGTESKAVSSPSKKGSPLIS 371
           L I N+ +L   ++  +  L  ++++ ++E   L  ++  +  E+  +    ++      
Sbjct: 610 L-INNVNDLQNNVDAEIRDLKVKLQEKDEEIDGLNEQIEQIIKENNDLKQKQEENQKENE 668

Query: 372 RKSGRNTASKMKSPWSQLSSETLNQDTDKKINKN---EIAKLEMVIQSLNKDLVDKEYVI 428
           +K   N   K +        E L +   +K  +N   E   L+  I+ L K++  ++Y  
Sbjct: 669 QKQKENEDLKKEVDDLTQEIEKLEEQKSQKEEENVNSEQENLQKQIEELKKEV--EQYKK 726

Query: 429 SEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQE 488
             +D            K   I Q Q+E  +     S   +    +D+ EIA   EQ K+ 
Sbjct: 727 QNEDLIEENEEMDEKMK---ILQKQIEEIKETNEESSEQIYALKKDL-EIA---EQEKER 779

Query: 489 LNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMI-KVKSNHKLKLKQMQKTIDNF 547
           +    ++ N+K+ I +LK   E+  ++++E     +++  + K   K  L +++K  + F
Sbjct: 780 IVKMEREQNMKE-ISQLKFEVEEKRRISEEYQNKCQSIAEEFKQREKKVLAEVEKKFNMF 838

Query: 548 SKVSD 552
               D
Sbjct: 839 KSAID 843


>UniRef50_A0DJQ4 Cluster: Chromosome undetermined scaffold_53, whole
            genome shotgun sequence; n=2; Paramecium tetraurelia|Rep:
            Chromosome undetermined scaffold_53, whole genome shotgun
            sequence - Paramecium tetraurelia
          Length = 1565

 Score =  166 bits (404), Expect = 4e-39
 Identities = 261/1137 (22%), Positives = 497/1137 (43%), Gaps = 109/1137 (9%)

Query: 473  EDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKV--K 530
            ED N+  K+++Q+ Q LND +     K L  +L+  + Q+ Q+ D+ D  NK ++K   +
Sbjct: 291  EDENK--KLRDQINQILND-LDQWRKKALTLELQVFDLQV-QVTDQ-DNNNKLLVKEIER 345

Query: 531  SNHKLKLKQ--MQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDY 588
             N +L  KQ  +++   N  +  D  KE+  L +++    + + EL+ +         D 
Sbjct: 346  LNQQLASKQQEIERLKTNLQQAEDHIKELQGLKQQIQEKQRVIDELKRKN--------DE 397

Query: 589  DSGRMIESDVYKKMIEMENLAETRL-KAISLLESQKFDLVQELHILQQKYDEVEDKLADI 647
             + +++E++  KK +E      T L K   +L  Q   L + L   QQ YD++ +KL  +
Sbjct: 398  QAKQLLENEKLKKQLEQIRGYNTDLQKQNGVLNYQIDQLNRTLENKQQAYDKLNNKLKFV 457

Query: 648  SQLQSD--QVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKED 705
                +   Q   EI  + +E+Q   LS    EL+ + + LKL  EQL    K+L+N +E 
Sbjct: 458  ENDNNTLRQQVLEINELQIEKQ-SLLS----ELSSLDKELKLKSEQLANVEKELQNLQEK 512

Query: 706  IMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIE 765
            +       I+  ++       M    I+EL  +I        + +  +   I +   Y++
Sbjct: 513  LQQL--RIIELELNRAKSQIDMKDRDIAELRKQIKDLTVKNFELEQRLKELISKETEYLK 570

Query: 766  NIESELSKYKSRICRLEESIAVMEDRRYSLERKAD---QLGSYLQEKQKAYSEYTIQEDE 822
             I  +   YKS   +L   +A +E     L+ + D   +L S L+  Q+ Y +      +
Sbjct: 571  -IFQQCETYKSLNDQLNLQLAQLEAENQQLQSQVDGLAELQSQLKVLQQKYEQTLKINSD 629

Query: 823  LVNRLAVLMDHDRVVEKQL----LEIEHENKELQKKNQILLEENQ---NLQISLSDMQQH 875
            L +R   L    + +++Q     L     N ELQ+ N +L +++Q   +L++ L+  +Q 
Sbjct: 630  LSSRNQQLQQQLQNIQQQKNVNNLRDNQINIELQRNNTLLNQKSQQIEDLRLKLAKAEQQ 689

Query: 876  Y----NALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIE 931
                 N L  K    D     + K Q ++++LES L  +    Q+L  Q      D  ++
Sbjct: 690  IDTLNNQLQNKQQELDNQIVLNAKLQDRIKELESELLNLKKTLQSLQDQNTSLKNDHHLQ 749

Query: 932  FNTQIESAIRDKKVLN----------EKYEKNIEYVTQL---EAQLQEY---KNNIENLN 975
                 E  +R ++ +           EKY +N   +  L   E +L +    KN + +LN
Sbjct: 750  LQELREEILRKQEEIKALQKLADQYKEKYLENDRQLADLKGLERKLNDITIQKNQLADLN 809

Query: 976  MNVEE-LNKMNLELIDKHVQKQQTQS-PDYTEQYINEINKLNALLKQKDEEIIALNQKIN 1033
               ++ ++K+  E     ++ Q+T    D  +QY   I KL A    K++EI  LN K+ 
Sbjct: 810  TAYQDQISKLQSENRSLQIKIQETHLFEDQNKQYEAIIEKLKAENTLKNKEITELNIKLP 869

Query: 1034 NAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIK 1093
                +YM  VSD E KL +   + +  + E++R+ ++  +  +  EEL+   +  + ++ 
Sbjct: 870  ----TYMQQVSDLEKKLLRTDQQFQIYKNEVERLRQEKQNLIKEIEELKRKNKNLEQKVN 925

Query: 1094 ELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQE 1153
            EL   +   E+ IP+ E        +  +   N VD            + +Q E+     
Sbjct: 926  ELNHLQ---EL-IPQLE--------QKANRLQNQVDKLSKQNLDYNDQINLQNEQ----- 968

Query: 1154 RSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNL 1213
               L +Q  ++ T L +  + + QLE+ N  L    + N +++   K +   LN E +  
Sbjct: 969  ---LSQQELQIRT-LFQVKSNLQQLES-NYSLVVQQL-NDQRLQSAKLEQAFLN-EQEQH 1021

Query: 1214 LSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKT---EHELRVQLSAFESKYEQ 1270
              T  EL+ + +  +DQ   +I +L K ++ + E    K    E EL+  +  F    + 
Sbjct: 1022 QKTADELKKA-TKELDQLKNKIEQLEK-YIKELEGKLIKDRILEQELKEAIG-FNLTLDT 1078

Query: 1271 LLDSVQSSTQEETNKIVTM-EQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIED 1329
             L+ V+   +   N+I  + E++   + K   K+  ++ LQ   A+ I Q+ I+  E+ D
Sbjct: 1079 KLNQVRQENESLKNEITQLKEELEQWKAKYLQKDNEVKTLQVYKAEAI-QMRIINDELTD 1137

Query: 1330 EKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQM---QEQSILNINEENAQ---LKKSSXX 1383
                                 DL+ +    KQ     EQ +  I     Q   L++    
Sbjct: 1138 NFNKLTKQLKAITLEKQIMEEDLQQQIADQKQRIAELEQLVAQIEPLQTQVNDLQQLVNK 1197

Query: 1384 XXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHE-YTITLTQRNDEFENVRQQLV 1442
                      ++ +A+ KV EL  ++E    E+ +K ++       ++  +    ++ L 
Sbjct: 1198 LQNENKLLAKKLGEAQTKVKELESKIEAY--EVMEKDYQKLQANYAEKAQDLRMTKEDLD 1255

Query: 1443 EYEKRIEDLTYEKES---ELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESV 1499
            +   +++ +T EKE+    +A+L  ++ E   H    ++E   E      +L+  + +  
Sbjct: 1256 KTTLQLDKVTKEKENLDMRIAMLAAEI-ERQKHLNKNKQEKIDELTNQNTDLSNVVAQLE 1314

Query: 1500 SLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQK 1556
             L+ +   L++ ++E   KT++ Q  L  ++ EI  LN+E+  LQN V     +I++
Sbjct: 1315 PLDPENTRLSEQIQEMKKKTDQDQLDLMKKDDEINKLNNEVYGLQNKVALLGPEIER 1371



 Score =  161 bits (392), Expect = 1e-37
 Identities = 259/1257 (20%), Positives = 538/1257 (42%), Gaps = 96/1257 (7%)

Query: 370  ISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVIS 429
            + +   R  A ++ S  S L   T   +   K+  +E  KL  +I+ L  +   K+  I+
Sbjct: 116  VEQWKARFFALQITSGGSGLEELTGMYEMRLKLLSDENGKLLALIKQLINENEQKDLAIA 175

Query: 430  EKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQEL 489
            ++D             D L   L+ +  +++E    +      E++   A+ QE    EL
Sbjct: 176  QRDNKIYQLELNQHEHDALQELLKKKQDENLELRGKLQ---GLEELLIDARKQEIENFEL 232

Query: 490  NDEIKDVNVKDLI--EKLKSAEEQITQLNDEIDAA--NKNMIKVKSNHKLKLKQMQKTID 545
              +IK++  +  +  +K K +EE   +L  E+       N + + S  + +L  M    D
Sbjct: 233  QSKIKNLENELAMWKDKFKLSEEDRNRLLQELRELLERMNQLNLDSVKRGQLSTMDLLED 292

Query: 546  NFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEM 605
               K+ D   +I ++  +L    +K   LE +  +LQ+ + D D+   +     +++ + 
Sbjct: 293  ENKKLRD---QINQILNDLDQWRKKALTLELQVFDLQVQVTDQDNNNKLLVKEIERLNQQ 349

Query: 606  ENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLE 665
                +  ++ +     Q  D ++EL  L+Q+  E +  + ++ +   +Q    +++  L+
Sbjct: 350  LASKQQEIERLKTNLQQAEDHIKELQGLKQQIQEKQRVIDELKRKNDEQAKQLLENEKLK 409

Query: 666  EQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTD--- 722
            +Q++ +     +L      L    +QL  T+++ +   + + NKL+    +N  L     
Sbjct: 410  KQLEQIRGYNTDLQKQNGVLNYQIDQLNRTLENKQQAYDKLNNKLKFVENDNNTLRQQVL 469

Query: 723  KLEKMSAEKISEL--LAKINHEEQSKIQTQFGIDAK---IQERDLYIENIESELSKYKSR 777
            ++ ++  EK S L  L+ ++ E + K +    ++ +   +QE+   +  IE EL++ KS+
Sbjct: 470  EINELQIEKQSLLSELSSLDKELKLKSEQLANVEKELQNLQEKLQQLRIIELELNRAKSQ 529

Query: 778  ICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVV 837
            I   +  IA +  +   L  K  +L   L+E     +EY     ++  +       +  +
Sbjct: 530  IDMKDRDIAELRKQIKDLTVKNFELEQRLKELISKETEYL----KIFQQCETYKSLNDQL 585

Query: 838  EKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQ 897
              QL ++E EN++LQ +   L E    L++     +Q      + ++R    + +    Q
Sbjct: 586  NLQLAQLEAENQQLQSQVDGLAELQSQLKVLQQKYEQTLKINSDLSSRNQQLQQQLQNIQ 645

Query: 898  TQ-----LRDLESNLKRITHEHQTLIVQKKKEIEDLEIEF---NTQIESAIRDKKVLNEK 949
             Q     LRD + N++     + TL+ QK ++IEDL ++      QI++     +   ++
Sbjct: 646  QQKNVNNLRDNQINIE--LQRNNTLLNQKSQQIEDLRLKLAKAEQQIDTLNNQLQNKQQE 703

Query: 950  YEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLEL-IDKHVQKQQTQSPDYTEQYI 1008
             +  I    +L+ +++E ++ + NL   ++ L   N  L  D H+Q Q+ +     +Q  
Sbjct: 704  LDNQIVLNAKLQDRIKELESELLNLKKTLQSLQDQNTSLKNDHHLQLQELREEILRKQ-- 761

Query: 1009 NEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVS 1068
             EI  L  L  Q  E+ +      N+ Q   ++ +   E KL   T +   + +      
Sbjct: 762  EEIKALQKLADQYKEKYLE-----NDRQ---LADLKGLERKLNDITIQKNQLADLNTAYQ 813

Query: 1069 KQLLDSKQHNEELQILVREQ---DDQIKELKE--TKLTFEMNIPKTEGMIISSTIEPMSD 1123
             Q+   +  N  LQI ++E    +DQ K+ +    KL  E  +   E   ++  +     
Sbjct: 814  DQISKLQSENRSLQIKIQETHLFEDQNKQYEAIIEKLKAENTLKNKEITELNIKLPTYMQ 873

Query: 1124 DANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNT 1183
              ++++               Q+ + +  E   L+++   L  E++E   K   LE    
Sbjct: 874  QVSDLEKKLLRTD--------QQFQIYKNEVERLRQEKQNLIKEIEELKRKNKNLEQKVN 925

Query: 1184 ELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSI---SSAVDQRGFEIAELW- 1239
            EL  H    QE I QL+ K  +L  + D L     +    I   +  + Q+  +I  L+ 
Sbjct: 926  EL-NH---LQELIPQLEQKANRLQNQVDKLSKQNLDYNDQINLQNEQLSQQELQIRTLFQ 981

Query: 1240 -KQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKI-VTMEQVTSLQN 1297
             K +L Q E+++     +L  Q     +K EQ   + Q   Q+  +++    +++  L+N
Sbjct: 982  VKSNLQQLESNYSLVVQQLNDQ-RLQSAKLEQAFLNEQEQHQKTADELKKATKELDQLKN 1040

Query: 1298 KLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQ 1357
            K++  E++++ L+ K    + +  IL  E++ E + F                 +R EN+
Sbjct: 1041 KIEQLEKYIKELEGK----LIKDRILEQELK-EAIGF-------NLTLDTKLNQVRQENE 1088

Query: 1358 SYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIY 1417
            S K      I  + EE  Q K  +            +V  AEA  + + +  EL D+   
Sbjct: 1089 SLK----NEITQLKEELEQWK--AKYLQKDNEVKTLQVYKAEAIQMRIIND-ELTDNFNK 1141

Query: 1418 QKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQ 1477
                   ITL ++  E E+++QQ+ + ++RI +L  +  +++  L+ ++++       +Q
Sbjct: 1142 LTKQLKAITLEKQIME-EDLQQQIADQKQRIAELE-QLVAQIEPLQTQVNDLQQLVNKLQ 1199

Query: 1478 KESEIERVKL------IEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEI 1531
             E+++   KL      ++EL  KI     + K   +L     E+       +  L+   +
Sbjct: 1200 NENKLLAKKLGEAQTKVKELESKIEAYEVMEKDYQKLQANYAEKAQDLRMTKEDLDKTTL 1259

Query: 1532 EIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAE 1588
            ++  +  E  NL   +   +++I++     +  KQ + ++L N  N +L + V + E
Sbjct: 1260 QLDKVTKEKENLDMRIAMLAAEIERQ-KHLNKNKQEKIDELTN-QNTDLSNVVAQLE 1314



 Score =  145 bits (351), Expect = 1e-32
 Identities = 239/1214 (19%), Positives = 518/1214 (42%), Gaps = 124/1214 (10%)

Query: 144  VTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXX 203
            +  L+ T++ K  A   L  K+K +E     L++++ E +++ + + ++           
Sbjct: 433  IDQLNRTLENKQQAYDKLNNKLKFVENDNNTLRQQVLEINEL-QIEKQSLLSELSSLDKE 491

Query: 204  XXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAA 263
                     + ++++  +QE    +    + E  R    I+ KD  I+ L +  K L   
Sbjct: 492  LKLKSEQLANVEKELQNLQEKLQQLRII-ELELNRAKSQIDMKDRDIAELRKQIKDLTVK 550

Query: 264  RFEIS----------LEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEK 313
             FE+            E+ K+ Q+ E               L  ++ +   +     E +
Sbjct: 551  NFELEQRLKELISKETEYLKIFQQCETYKSLNDQLNLQLAQLEAENQQLQSQVDGLAELQ 610

Query: 314  GSLEIANMT-ELTKKIEL-LEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLIS 371
              L++     E T KI   L   N Q++Q  + ++ +          ++   ++ + L++
Sbjct: 611  SQLKVLQQKYEQTLKINSDLSSRNQQLQQQLQNIQQQKNVNNLRDNQINIELQRNNTLLN 670

Query: 372  RKSGRNTASKMKSPWSQLSSETLNQDTDKKINK--NEIAKLEMVIQSLNKDLVDKEYVIS 429
            +KS +    ++K   ++   +TLN     K  +  N+I  L   +Q   K+L  +  +++
Sbjct: 671  QKSQQIEDLRLKLAKAEQQIDTLNNQLQNKQQELDNQIV-LNAKLQDRIKELESE--LLN 727

Query: 430  EKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQE- 488
             K T           K+    QLQ   ++ +            E++  + K+ +Q K++ 
Sbjct: 728  LKKTLQSLQDQNTSLKNDHHLQLQELREEILR---------KQEEIKALQKLADQYKEKY 778

Query: 489  LNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFS 548
            L ++ +  ++K L  KL     Q  QL D   A    + K++S ++     +Q  I    
Sbjct: 779  LENDRQLADLKGLERKLNDITIQKNQLADLNTAYQDQISKLQSENR----SLQIKIQETH 834

Query: 549  KVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENL 608
               D NK+   + E+L   ++   +  +E   L + L  Y       SD+ KK++  +  
Sbjct: 835  LFEDQNKQYEAIIEKLK--AENTLK-NKEITELNIKLPTY---MQQVSDLEKKLLRTDQQ 888

Query: 609  AETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQI 668
             +     +  L  +K +L++E+  L++K   +E K+ +++ LQ      E K+  L+ Q+
Sbjct: 889  FQIYKNEVERLRQEKQNLIKEIEELKRKNKNLEQKVNELNHLQELIPQLEQKANRLQNQV 948

Query: 669  DALSASKKEL--ALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEK 726
            D LS    +    + ++N +L +++L   I+ L   K ++     NY      L D  ++
Sbjct: 949  DKLSKQNLDYNDQINLQNEQLSQQELQ--IRTLFQVKSNLQQLESNYSLVVQQLND--QR 1004

Query: 727  MSAEKISELLAKINHEEQ--------SKIQTQFG-IDAKIQERDLYIENIESELSKYKSR 777
            + + K+ +  A +N +EQ         K   +   +  KI++ + YI+ +E +L K +  
Sbjct: 1005 LQSAKLEQ--AFLNEQEQHQKTADELKKATKELDQLKNKIEQLEKYIKELEGKLIKDRIL 1062

Query: 778  ICRLEESIA---VMEDRRYSLERKADQLGS---YLQEKQKAYSEYTIQEDELVNRLAVLM 831
               L+E+I     ++ +   + ++ + L +    L+E+ + +    +Q+D  V  L V  
Sbjct: 1063 EQELKEAIGFNLTLDTKLNQVRQENESLKNEITQLKEELEQWKAKYLQKDNEVKTLQVYK 1122

Query: 832  DHD---RVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDL 888
                  R++  +L +  + NK  ++   I LE+    QI   D+QQ      ++    + 
Sbjct: 1123 AEAIQMRIINDELTD--NFNKLTKQLKAITLEK----QIMEEDLQQQIADQKQRIAELEQ 1176

Query: 889  AESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNE 948
              ++    QTQ+ DL+  + ++ +E++ L     K++ + + +   ++ES I   +V+ +
Sbjct: 1177 LVAQIEPLQTQVNDLQQLVNKLQNENKLLA----KKLGEAQTKVK-ELESKIEAYEVMEK 1231

Query: 949  KYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYI 1008
             Y+K       L+A    Y    ++L M  E+L+K  L+L DK V K++           
Sbjct: 1232 DYQK-------LQAN---YAEKAQDLRMTKEDLDKTTLQL-DK-VTKEKENLDMRIAMLA 1279

Query: 1009 NEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVS 1068
             EI +   L K K E+I  L  +                + L+    +LE ++ E  R+S
Sbjct: 1280 AEIERQKHLNKNKQEKIDELTNQ---------------NTDLSNVVAQLEPLDPENTRLS 1324

Query: 1069 KQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNV 1128
            +Q+ + K+  ++ Q+ + ++DD+I +L       +  +      ++   IE      N  
Sbjct: 1325 EQIQEMKKKTDQDQLDLMKKDDEINKLNNEVYGLQNKVA-----LLGPEIERAKLKYNGA 1379

Query: 1129 DXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGH 1188
                           ++E EE +Q+   LQ++   L+  L +   K+  LE  N  L   
Sbjct: 1380 QNT------------IKELEEKLQDYEHLQQELGNLDNALNQAEEKVQNLEKENNTLHQT 1427

Query: 1189 DVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREA 1248
                 +++NQ K+ +  L  +  NLL+     +  + + + Q+  E  +L K+ + Q + 
Sbjct: 1428 LTAKSDELNQAKANVNDLQNQL-NLLNEQLINQQQLENELQQKDHENQQL-KEKIGQLQQ 1485

Query: 1249 DFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVT-SLQNKLQDKEEHLR 1307
              ++ E +++       +     +++++   Q   NK+   E +   L + L + ++H++
Sbjct: 1486 QIEQLE-QIKYDNEGKIAMLATQIEALKYKYQVAENKLKEQENIIGQLNDDLDNFDKHIQ 1544

Query: 1308 NLQEKYADVINQIE 1321
             L+ +  D+ ++++
Sbjct: 1545 ELEGENQDLKDKMQ 1558



 Score =  142 bits (343), Expect = 9e-32
 Identities = 258/1373 (18%), Positives = 575/1373 (41%), Gaps = 100/1373 (7%)

Query: 216  QQMTKMQENFIAMEAEWKD-------EKQRLLKDIESKDVRISSLE-EANKLLEAARFEI 267
            Q   K  EN +AM   WKD       ++ RLL+++     R++ L  ++ K  + +  ++
Sbjct: 233  QSKIKNLENELAM---WKDKFKLSEEDRNRLLQELRELLERMNQLNLDSVKRGQLSTMDL 289

Query: 268  -SLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSL--EIANMTE- 323
               E+ KL  ++ Q              L  Q  +   +   +      L  EI  + + 
Sbjct: 290  LEDENKKLRDQINQILNDLDQWRKKALTLELQVFDLQVQVTDQDNNNKLLVKEIERLNQQ 349

Query: 324  LTKKIELLEHLNCQIRQTN---KELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTAS 380
            L  K + +E L   ++Q     KEL+  L     E + V    K+ +   +++   N   
Sbjct: 350  LASKQQEIERLKTNLQQAEDHIKELQG-LKQQIQEKQRVIDELKRKNDEQAKQLLEN--E 406

Query: 381  KMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNK--DLVDKEYVISEKDTXXXXX 438
            K+K    Q+     +      +   +I +L   +++  +  D ++ +    E D      
Sbjct: 407  KLKKQLEQIRGYNTDLQKQNGVLNYQIDQLNRTLENKQQAYDKLNNKLKFVENDNNTLRQ 466

Query: 439  XXXXXG-----KDTLIAQLQ-LEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDE 492
                       K +L+++L  L+ +  ++   L +V    +++ E  +    ++ ELN  
Sbjct: 467  QVLEINELQIEKQSLLSELSSLDKELKLKSEQLANVEKELQNLQEKLQQLRIIELELNRA 526

Query: 493  IKDVNVKDL-IEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVS 551
               +++KD  I +L+   + +T  N E++   K +I  K    LK+ Q  +T  + +   
Sbjct: 527  KSQIDMKDRDIAELRKQIKDLTVKNFELEQRLKELIS-KETEYLKIFQQCETYKSLN--D 583

Query: 552  DSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAET 611
              N ++ +L  E   L  +V  L E +  L++    Y+    I SD+  +  +++   + 
Sbjct: 584  QLNLQLAQLEAENQQLQSQVDGLAELQSQLKVLQQKYEQTLKINSDLSSRNQQLQQQLQN 643

Query: 612  --RLKAISLLESQKFDLVQELH--ILQQKYDEVED---KLADISQLQSDQVCSEIKSVHL 664
              + K ++ L   + ++  + +  +L QK  ++ED   KLA   Q Q D + +++++   
Sbjct: 644  IQQQKNVNNLRDNQINIELQRNNTLLNQKSQQIEDLRLKLAKAEQ-QIDTLNNQLQNK-- 700

Query: 665  EEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQE-NMDLTDK 723
            ++++D       +L   I+ L+ +   L  T++ L++    + N     +QE   ++  K
Sbjct: 701  QQELDNQIVLNAKLQDRIKELESELLNLKKTLQSLQDQNTSLKNDHHLQLQELREEILRK 760

Query: 724  LEKMSA-EKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLE 782
             E++ A +K+++   +   E   ++    G++ K+ +  +    +    + Y+ +I +L+
Sbjct: 761  QEEIKALQKLADQYKEKYLENDRQLADLKGLERKLNDITIQKNQLADLNTAYQDQISKLQ 820

Query: 783  ESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVN---RLAVLMDHDRVVEK 839
                 ++ +        DQ   Y    +K  +E T++  E+     +L   M     +EK
Sbjct: 821  SENRSLQIKIQETHLFEDQNKQYEAIIEKLKAENTLKNKEITELNIKLPTYMQQVSDLEK 880

Query: 840  QLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQ 899
            +LL  + + +  + + + L +E QNL   + ++++    L +K N  +  +    + + +
Sbjct: 881  KLLRTDQQFQIYKNEVERLRQEKQNLIKEIEELKRKNKNLEQKVNELNHLQELIPQLEQK 940

Query: 900  LRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQ 959
               L++ + +++ ++     Q   + E L  +   QI +  + K  L ++ E N   V Q
Sbjct: 941  ANRLQNQVDKLSKQNLDYNDQINLQNEQLSQQ-ELQIRTLFQVKSNL-QQLESNYSLVVQ 998

Query: 960  LEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQK--QQTQSPDYTEQYINEIN-KL-- 1014
                 +     +E   +N +E ++   + + K  ++  Q     +  E+YI E+  KL  
Sbjct: 999  QLNDQRLQSAKLEQAFLNEQEQHQKTADELKKATKELDQLKNKIEQLEKYIKELEGKLIK 1058

Query: 1015 NALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDS 1074
            + +L+Q+ +E I  N  ++             ++++ Q   +LE  + +  +   ++   
Sbjct: 1059 DRILEQELKEAIGFNLTLDTKLNQVRQENESLKNEITQLKEELEQWKAKYLQKDNEVKTL 1118

Query: 1075 KQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXX 1134
            + +  E  I +R  +D++ +    KLT ++     E  I+   ++    D          
Sbjct: 1119 QVYKAEA-IQMRIINDELTD-NFNKLTKQLKAITLEKQIMEEDLQQQIADQKQRIAELEQ 1176

Query: 1135 XXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQE 1194
                   L+ Q  +   Q  + LQ ++  L  +L E  TK+ +LE+   ++  ++V+ ++
Sbjct: 1177 LVAQIEPLQTQVND-LQQLVNKLQNENKLLAKKLGEAQTKVKELES---KIEAYEVMEKD 1232

Query: 1195 ----QINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADF 1250
                Q N  + K + L    ++L  T  +L   ++   +     IA L  +   Q+  + 
Sbjct: 1233 YQKLQANYAE-KAQDLRMTKEDLDKTTLQL-DKVTKEKENLDMRIAMLAAEIERQKHLNK 1290

Query: 1251 QKTEH--ELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSL-QNKLQDKEEHLR 1307
             K E   EL  Q +   +   QL + +       + +I  M++ T   Q  L  K++ + 
Sbjct: 1291 NKQEKIDELTNQNTDLSNVVAQL-EPLDPENTRLSEQIQEMKKKTDQDQLDLMKKDDEIN 1349

Query: 1308 NLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXX------DLRTENQSYKQ 1361
             L  +   + N++ +L  EIE  K+ +                      +L   + +  Q
Sbjct: 1350 KLNNEVYGLQNKVALLGPEIERAKLKYNGAQNTIKELEEKLQDYEHLQQELGNLDNALNQ 1409

Query: 1362 MQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQL---ELKDSEIYQ 1418
             +E+ + N+ +EN  L ++              VND + ++  L  QL   +  ++E+ Q
Sbjct: 1410 AEEK-VQNLEKENNTLHQTLTAKSDELNQAKANVNDLQNQLNLLNEQLINQQQLENELQQ 1468

Query: 1419 KTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQK 1478
            K HE        N + +    QL +  +++E + Y+ E ++A+L       A   E ++ 
Sbjct: 1469 KDHE--------NQQLKEKIGQLQQQIEQLEQIKYDNEGKIAML-------ATQIEALKY 1513

Query: 1479 ESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEI 1531
            + ++   KL E+ N+       LN  +   +K ++E   +  +++  ++ Q I
Sbjct: 1514 KYQVAENKLKEQENI----IGQLNDDLDNFDKHIQELEGENQDLKDKMQQQSI 1562



 Score =  116 bits (280), Expect = 4e-24
 Identities = 231/1198 (19%), Positives = 514/1198 (42%), Gaps = 118/1198 (9%)

Query: 213  DTKQQMTKMQENFIAMEAEWKDEKQRLL---KDIESKDVRISSLEEANKLLEAARFEISL 269
            D + Q+T    N   +  E +   Q+L    ++IE     +   E+  K L+  + +I  
Sbjct: 324  DLQVQVTDQDNNNKLLVKEIERLNQQLASKQQEIERLKTNLQQAEDHIKELQGLKQQIQ- 382

Query: 270  EHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIE 329
            E  ++  EL++              L KQ +E      T+++++  +    + +L + +E
Sbjct: 383  EKQRVIDELKRKNDEQAKQLLENEKLKKQ-LEQIRGYNTDLQKQNGVLNYQIDQLNRTLE 441

Query: 330  LLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQL 389
              +    ++    K +EN   T+  +   ++    +   L+S  S  +   K+KS   QL
Sbjct: 442  NKQQAYDKLNNKLKFVENDNNTLRQQVLEINELQIEKQSLLSELSSLDKELKLKS--EQL 499

Query: 390  SS-ETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTL 448
            ++ E   Q+  +K+ +  I +LE+       D+ D++  I+E               +  
Sbjct: 500  ANVEKELQNLQEKLQQLRIIELELNRAKSQIDMKDRD--IAELRKQIKDLTVKNFELEQR 557

Query: 449  IAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQ-EQLKQELNDEIKDV-NVKDLIEKLK 506
            + +L  +  ++++         +  D   +   Q E   Q+L  ++  +  ++  ++ L+
Sbjct: 558  LKELISKETEYLKIFQQCETYKSLNDQLNLQLAQLEAENQQLQSQVDGLAELQSQLKVLQ 617

Query: 507  SAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFS------KVSDSNKEIVRL 560
               EQ  ++N ++ + N+ +       +L+  Q QK ++N        ++  +N  + + 
Sbjct: 618  QKYEQTLKINSDLSSRNQQL-----QQQLQNIQQQKNVNNLRDNQINIELQRNNTLLNQK 672

Query: 561  TEELHHLSQKVAELEEE----KGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAI 616
            ++++  L  K+A+ E++       LQ    + D+  ++ + +  ++ E+E+      K +
Sbjct: 673  SQQIEDLRLKLAKAEQQIDTLNNQLQNKQQELDNQIVLNAKLQDRIKELESELLNLKKTL 732

Query: 617  SLLESQKFDLVQELHI-LQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASK 675
              L+ Q   L  + H+ LQ+  +E+  K  +I  LQ  ++  + K  +LE   D   A  
Sbjct: 733  QSLQDQNTSLKNDHHLQLQELREEILRKQEEIKALQ--KLADQYKEKYLEN--DRQLADL 788

Query: 676  KELALVIENLKLDKEQL-------YGTIKDLENDKEDIMNKLQN---YIQENMDLTDKLE 725
            K L   + ++ + K QL          I  L+++   +  K+Q    +  +N      +E
Sbjct: 789  KGLERKLNDITIQKNQLADLNTAYQDQISKLQSENRSLQIKIQETHLFEDQNKQYEAIIE 848

Query: 726  KMSAEKI--SELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEE 783
            K+ AE    ++ + ++N +  + +Q    ++ K+   D   +  ++E+ + +     L +
Sbjct: 849  KLKAENTLKNKEITELNIKLPTYMQQVSDLEKKLLRTDQQFQIYKNEVERLRQEKQNLIK 908

Query: 784  SIAVMEDRRYSLERKADQLGSYLQE-----KQKAYSEYTIQEDELVNRLAVLMDHDRVVE 838
             I  ++ +  +LE+K ++L ++LQE     +QKA +    Q D+L  +     D   +  
Sbjct: 909  EIEELKRKNKNLEQKVNEL-NHLQELIPQLEQKA-NRLQNQVDKLSKQNLDYNDQINLQN 966

Query: 839  KQLLEIEHENKEL--QKKNQILLEENQNLQISLSDMQQHYNALVEKA--------NRTDL 888
            +QL + E + + L   K N   LE N +L +   + Q+  +A +E+A         +T  
Sbjct: 967  EQLSQQELQIRTLFQVKSNLQQLESNYSLVVQQLNDQRLQSAKLEQAFLNEQEQHQKTAD 1026

Query: 889  AESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLE--IEFNTQIESAIRDKKVL 946
               ++TK   QL++    L++   E +  +++ +   ++L+  I FN  +++ +   +  
Sbjct: 1027 ELKKATKELDQLKNKIEQLEKYIKELEGKLIKDRILEQELKEAIGFNLTLDTKLNQVRQE 1086

Query: 947  NEKYEKNIEYVTQLEAQLQEYK-------NNIENLNMNVEE--------------LNKMN 985
            NE  +  I   TQL+ +L+++K       N ++ L +   E               NK+ 
Sbjct: 1087 NESLKNEI---TQLKEELEQWKAKYLQKDNEVKTLQVYKAEAIQMRIINDELTDNFNKLT 1143

Query: 986  LEL----IDKHVQKQQTQSPDYTE-QYINEINKLNALLKQKDEEIIALNQKINNAQVSYM 1040
             +L    ++K + ++  Q     + Q I E+ +L A ++    ++  L Q +N  Q    
Sbjct: 1144 KQLKAITLEKQIMEEDLQQQIADQKQRIAELEQLVAQIEPLQTQVNDLQQLVNKLQNENK 1203

Query: 1041 SM---VSDYESKLAQFTTKLEN---MEEEMQRV----SKQLLDSKQHNEELQILVREQDD 1090
             +   + + ++K+ +  +K+E    ME++ Q++    +++  D +   E+L     + D 
Sbjct: 1204 LLAKKLGEAQTKVKELESKIEAYEVMEKDYQKLQANYAEKAQDLRMTKEDLDKTTLQLDK 1263

Query: 1091 QIKELKETKLTFEMNIPKTEGMI-ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEE 1149
              KE +   +   M   + E    ++   +   D+  N +            L    E  
Sbjct: 1264 VTKEKENLDMRIAMLAAEIERQKHLNKNKQEKIDELTNQNTDLSNVVAQLEPL--DPENT 1321

Query: 1150 FIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTE 1209
             + E+  +QE   K + +  +   K  ++  LN E+ G     Q ++  L  ++E+   +
Sbjct: 1322 RLSEQ--IQEMKKKTDQDQLDLMKKDDEINKLNNEVYGL----QNKVALLGPEIERAKLK 1375

Query: 1210 NDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYE 1269
             +   +T+ EL   +    +    E+  L    L Q E   Q  E E         +K +
Sbjct: 1376 YNGAQNTIKELEEKLQD-YEHLQQELGNL-DNALNQAEEKVQNLEKENNTLHQTLTAKSD 1433

Query: 1270 QLLDSVQSSTQEETNKIVTM-EQVTS---LQNKLQDKEEHLRNLQEKYADVINQIEIL 1323
            +L +  +++  +  N++  + EQ+ +   L+N+LQ K+   + L+EK   +  QIE L
Sbjct: 1434 EL-NQAKANVNDLQNQLNLLNEQLINQQQLENELQQKDHENQQLKEKIGQLQQQIEQL 1490



 Score =  100 bits (240), Expect = 3e-19
 Identities = 200/1046 (19%), Positives = 456/1046 (43%), Gaps = 76/1046 (7%)

Query: 91   SESLANTLKQKEILMEKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNT 150
            SE LAN  K+ + L EK++Q + +    +    +               Q+ D+T  +  
Sbjct: 496  SEQLANVEKELQNLQEKLQQLRIIELELNR--AKSQIDMKDRDIAELRKQIKDLTVKNFE 553

Query: 151  IKEKDNALSVLQVK-MKIME--TTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXX 207
            ++++   L   + + +KI +   T   L +++N +   +EA+N+                
Sbjct: 554  LEQRLKELISKETEYLKIFQQCETYKSLNDQLNLQLAQLEAENQQLQSQVDGLAELQSQL 613

Query: 208  XXXXEDTKQQMTKMQENFIAMEAEWKDEKQRL--LKDIES-KDVRIS-SLEEANKLLEAA 263
                +  +Q + K+  +  +   + + + Q +   K++ + +D +I+  L+  N LL   
Sbjct: 614  KVLQQKYEQTL-KINSDLSSRNQQLQQQLQNIQQQKNVNNLRDNQINIELQRNNTLLNQK 672

Query: 264  RFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTE 323
              +I     KLA+  +Q              L  Q I  + + +  I+E  S E+ N   
Sbjct: 673  SQQIEDLRLKLAKAEQQIDTLNNQLQNKQQELDNQ-IVLNAKLQDRIKELES-ELLN--- 727

Query: 324  LTKKIELLEHLNCQIRQTN----KELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTA 379
            L K ++ L+  N  ++  +    +EL  ++     E KA+   + +       ++ R  A
Sbjct: 728  LKKTLQSLQDQNTSLKNDHHLQLQELREEILRKQEEIKALQKLADQYKEKY-LENDRQLA 786

Query: 380  SKMKSPWSQLSSETLNQDTDKKIN---KNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXX 436
              +K    +L+  T+ ++    +N   +++I+KL+   +SL +  + + ++  +++    
Sbjct: 787  D-LKGLERKLNDITIQKNQLADLNTAYQDQISKLQSENRSL-QIKIQETHLFEDQNKQYE 844

Query: 437  XXXXXXXGKDTL----IAQLQLEHQQHMEGPS-LIHVGTNTEDVNEIAKVQ-EQLKQELN 490
                    ++TL    I +L ++   +M+  S L      T+   +I K + E+L+QE  
Sbjct: 845  AIIEKLKAENTLKNKEITELNIKLPTYMQQVSDLEKKLLRTDQQFQIYKNEVERLRQEKQ 904

Query: 491  DEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKV 550
            + IK+  +++L  K K+ E+++ +LN        ++ ++    + K  ++Q  +D  SK 
Sbjct: 905  NLIKE--IEELKRKNKNLEQKVNELN--------HLQELIPQLEQKANRLQNQVDKLSKQ 954

Query: 551  S-DSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLA 609
            + D N +I    E+L     ++  L + K NLQ    +Y    ++   +  + ++   L 
Sbjct: 955  NLDYNDQINLQNEQLSQQELQIRTLFQVKSNLQQLESNYS---LVVQQLNDQRLQSAKLE 1011

Query: 610  ETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQID 669
            +  L      + Q      EL    ++ D++++K+  + +   +     IK   LE+++ 
Sbjct: 1012 QAFLNE----QEQHQKTADELKKATKELDQLKNKIEQLEKYIKELEGKLIKDRILEQELK 1067

Query: 670  ALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSA 729
                    L   +  ++ + E L   I  L   KE++      Y+Q++ ++   L+   A
Sbjct: 1068 EAIGFNLTLDTKLNQVRQENESLKNEITQL---KEELEQWKAKYLQKDNEV-KTLQVYKA 1123

Query: 730  EKIS-ELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVM 788
            E I   ++     +  +K+  Q  + A   E+ +  E+++ +++  K RI  LE+ +A +
Sbjct: 1124 EAIQMRIINDELTDNFNKLTKQ--LKAITLEKQIMEEDLQQQIADQKQRIAELEQLVAQI 1181

Query: 789  EDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHEN 848
            E  +  +     QL + LQ + K  ++   +    V  L   ++   V+EK   +++   
Sbjct: 1182 EPLQTQV-NDLQQLVNKLQNENKLLAKKLGEAQTKVKELESKIEAYEVMEKDYQKLQANY 1240

Query: 849  KELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLK 908
             E  +  ++  E+     + L  + +    L  +      AE E  K+    ++ +  + 
Sbjct: 1241 AEKAQDLRMTKEDLDKTTLQLDKVTKEKENLDMRIAML-AAEIERQKHLN--KNKQEKID 1297

Query: 909  RITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYE----KNIEYVTQLEAQL 964
             +T+++ T +     ++E L+ E NT++   I++ K   ++ +    K  + + +L  ++
Sbjct: 1298 ELTNQN-TDLSNVVAQLEPLDPE-NTRLSEQIQEMKKKTDQDQLDLMKKDDEINKLNNEV 1355

Query: 965  QEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEE 1024
               +N +  L   +E   K+        +++ + +  DY E    E+  L+  L Q +E+
Sbjct: 1356 YGLQNKVALLGPEIERA-KLKYNGAQNTIKELEEKLQDY-EHLQQELGNLDNALNQAEEK 1413

Query: 1025 IIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQIL 1084
            +  L +K NN     ++  SD   +L Q    + +++ ++  +++QL++ +Q   ELQ  
Sbjct: 1414 VQNL-EKENNTLHQTLTAKSD---ELNQAKANVNDLQNQLNLLNEQLINQQQLENELQ-- 1467

Query: 1085 VREQDDQIKELKETKLTFEMNIPKTE 1110
              ++D + ++LKE     +  I + E
Sbjct: 1468 --QKDHENQQLKEKIGQLQQQIEQLE 1491



 Score = 98.3 bits (234), Expect = 2e-18
 Identities = 169/850 (19%), Positives = 385/850 (45%), Gaps = 69/850 (8%)

Query: 174  DLQEKINEKDQIIEAKNK-ATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIA-MEAE 231
            +L+E+I  K + I+A  K A                    + K     +Q+N +A +   
Sbjct: 752  ELREEILRKQEEIKALQKLADQYKEKYLENDRQLADLKGLERKLNDITIQKNQLADLNTA 811

Query: 232  WKDEKQRLLKDIESKDVRISS---LEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXX 288
            ++D+  +L  +  S  ++I      E+ NK  EA   ++  E++   +E+ +        
Sbjct: 812  YQDQISKLQSENRSLQIKIQETHLFEDQNKQYEAIIEKLKAENTLKNKEITELNIKLPTY 871

Query: 289  XXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENK 348
                  L K+ +    +++ +I +    E+  + +  +K  L++ +  ++++ NK LE K
Sbjct: 872  MQQVSDLEKKLLRT--DQQFQIYKN---EVERLRQ--EKQNLIKEIE-ELKRKNKNLEQK 923

Query: 349  LATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIA 408
            +  +    + +        P + +K     A+++++   +LS + L+ +    +   +++
Sbjct: 924  VNELNHLQELI--------PQLEQK-----ANRLQNQVDKLSKQNLDYNDQINLQNEQLS 970

Query: 409  KLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHV 468
            + E+ I++L +   + + + S                  L      E +QH +    +  
Sbjct: 971  QQELQIRTLFQVKSNLQQLESNYSLVVQQLNDQRLQSAKLEQAFLNEQEQHQKTADELKK 1030

Query: 469  GTNTEDV--NEIAKVQEQLKQE----LNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAA 522
             T   D   N+I ++++ +K+     + D I +  +K+ I    + + ++ Q+  E ++ 
Sbjct: 1031 ATKELDQLKNKIEQLEKYIKELEGKLIKDRILEQELKEAIGFNLTLDTKLNQVRQENESL 1090

Query: 523  NKNMIKVKSN-HKLKLKQMQKTIDNFSKVSDSNK-EIVRLTEELHHLSQKVAELEEEKG- 579
               + ++K    + K K +QK  DN  K     K E +++      L+    +L ++   
Sbjct: 1091 KNEITQLKEELEQWKAKYLQK--DNEVKTLQVYKAEAIQMRIINDELTDNFNKLTKQLKA 1148

Query: 580  -NLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYD 638
              L+  +++ D  + I +D  +++ E+E L    +  I  L++Q  DL Q ++ LQ +  
Sbjct: 1149 ITLEKQIMEEDLQQQI-ADQKQRIAELEQL----VAQIEPLQTQVNDLQQLVNKLQNENK 1203

Query: 639  EVEDKLADISQLQSDQVCSEIKSVH-LEEQIDALSASKKELALVIENLKLDKEQLYGTIK 697
             +  KL + +Q +  ++ S+I++   +E+    L A+  E A   ++L++ KE L  T  
Sbjct: 1204 LLAKKLGE-AQTKVKELESKIEAYEVMEKDYQKLQANYAEKA---QDLRMTKEDLDKTTL 1259

Query: 698  DLEN---DKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGID 754
             L+    +KE++  ++     E ++    L K   EKI EL  + N +  + +     +D
Sbjct: 1260 QLDKVTKEKENLDMRIAMLAAE-IERQKHLNKNKQEKIDELTNQ-NTDLSNVVAQLEPLD 1317

Query: 755  AKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYS 814
             +       I+ ++ +  + +  + + ++ I  + +  Y L+ K   LG  ++  +  Y+
Sbjct: 1318 PENTRLSEQIQEMKKKTDQDQLDLMKKDDEINKLNNEVYGLQNKVALLGPEIERAKLKYN 1377

Query: 815  EYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQ 874
                   EL  +L    D++ + +++L  +++   + ++K Q L +EN  L  +L+    
Sbjct: 1378 GAQNTIKELEEKL---QDYEHL-QQELGNLDNALNQAEEKVQNLEKENNTLHQTLTAKSD 1433

Query: 875  HYNALVEKANRTDLAESESTKYQTQL---RDLESNLKRITHEHQTL---IVQKKKEIEDL 928
              N    KAN  DL +++      QL   + LE+ L++  HE+Q L   I Q +++IE L
Sbjct: 1434 ELNQA--KANVNDL-QNQLNLLNEQLINQQQLENELQQKDHENQQLKEKIGQLQQQIEQL 1490

Query: 929  E-IEFNTQIESAIRDKKV--LNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMN 985
            E I+++ + + A+   ++  L  KY+     + + E  + +  ++++N + +++EL   N
Sbjct: 1491 EQIKYDNEGKIAMLATQIEALKYKYQVAENKLKEQENIIGQLNDDLDNFDKHIQELEGEN 1550

Query: 986  LELIDKHVQK 995
             +L DK  Q+
Sbjct: 1551 QDLKDKMQQQ 1560



 Score = 75.8 bits (178), Expect = 9e-12
 Identities = 125/587 (21%), Positives = 251/587 (42%), Gaps = 56/587 (9%)

Query: 148  SNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXX 207
            ++ +K+    L  L+ K++ +E  I +L+ K+  KD+I+E + K                
Sbjct: 1025 ADELKKATKELDQLKNKIEQLEKYIKELEGKLI-KDRILEQELKEAIGFNLTLDTKLNQV 1083

Query: 208  XXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEI 267
                E  K ++T+++E       +WK   + L KD E K +++   E     +     E+
Sbjct: 1084 RQENESLKNEITQLKEEL----EQWK--AKYLQKDNEVKTLQVYKAEAIQ--MRIINDEL 1135

Query: 268  SLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKK 327
            +   +KL ++L+               + +   +   ++K  I E   L +A +  L  +
Sbjct: 1136 TDNFNKLTKQLK-------AITLEKQIMEEDLQQQIADQKQRIAELEQL-VAQIEPLQTQ 1187

Query: 328  IELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLIS--RKSGRNTASKMKSP 385
            +  L+ L  +++  NK L  KL    T+ K + S  +    +    +K   N A K +  
Sbjct: 1188 VNDLQQLVNKLQNENKLLAKKLGEAQTKVKELESKIEAYEVMEKDYQKLQANYAEKAQD- 1246

Query: 386  WSQLSSETLNQDTDK--KINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXX 443
              +++ E L++ T +  K+ K E   L+M I  L  ++  ++++   K            
Sbjct: 1247 -LRMTKEDLDKTTLQLDKVTK-EKENLDMRIAMLAAEIERQKHLNKNKQEKIDELTNQNT 1304

Query: 444  GKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIE 503
                ++AQL+       E   L      +E + E+ K  +Q + +L    KD  +  L  
Sbjct: 1305 DLSNVVAQLE---PLDPENTRL------SEQIQEMKKKTDQDQLDLMK--KDDEINKLNN 1353

Query: 504  KLKSAEEQITQLNDEIDAANKNMIKVKSNHKLK-LKQMQKTIDNFSKVSDSNKEIVRLTE 562
            ++   + ++  L  EI+ A     K+K N     +K++++ + ++  +    +E+  L  
Sbjct: 1354 EVYGLQNKVALLGPEIERA-----KLKYNGAQNTIKELEEKLQDYEHLQ---QELGNLDN 1405

Query: 563  ELHHLSQKVAELEEEKGNLQLHLV-DYDSGRMIESDVYKKMIEMENLAETRLKAISLLES 621
             L+   +KV  LE+E   L   L    D     +++V     ++ NL   +L     LE+
Sbjct: 1406 ALNQAEEKVQNLEKENNTLHQTLTAKSDELNQAKANVNDLQNQL-NLLNEQLINQQQLEN 1464

Query: 622  QKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALV 681
            +      E   L++K  +++ ++  + Q++ D   +E K   L  QI+AL    +    V
Sbjct: 1465 ELQQKDHENQQLKEKIGQLQQQIEQLEQIKYD---NEGKIAMLATQIEALKYKYQ----V 1517

Query: 682  IENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMS 728
             EN   ++E + G + D   D ++    +Q    EN DL DK+++ S
Sbjct: 1518 AENKLKEQENIIGQLND---DLDNFDKHIQELEGENQDLKDKMQQQS 1561


>UniRef50_A0BIQ2 Cluster: Chromosome undetermined scaffold_11, whole
            genome shotgun sequence; n=1; Paramecium tetraurelia|Rep:
            Chromosome undetermined scaffold_11, whole genome shotgun
            sequence - Paramecium tetraurelia
          Length = 2447

 Score =  166 bits (403), Expect = 5e-39
 Identities = 281/1420 (19%), Positives = 604/1420 (42%), Gaps = 113/1420 (7%)

Query: 231  EWKDEKQRLLKDIESKDVRISSLEE-ANKLLEAARFEISLEHSKLAQE-LEQXXXXXXXX 288
            E+  + Q+L K+I++   +++  EE  N++++  + EI+   S+L Q+ LE+        
Sbjct: 286  EYSKQIQQLNKEIQTYKQQLAQQEEQCNRIVQQKQKEINQVQSQLEQKHLEETLKKQQQN 345

Query: 289  XXXXXXLAKQ--SIEPSC----EEKTEIEEKGSLEIANMTELTKKIEL-LEHLNCQIRQT 341
                  + +Q  S++       +E + +++K    + N+ +  K+++L L++L       
Sbjct: 346  EQQYLQVIEQFNSLQNKIALLEDENSSLKQKSFKTLKNVVQELKRMKLELQNLKMMGHYD 405

Query: 342  NKELEN-KLATMGTESKAVSSPSKKGS---PLISRKSGRNTASKMKSPWSQLSSETLNQD 397
              +L   +   M    +A+S P K       ++   S   + ++     +QL  + +   
Sbjct: 406  ISQLNGLEQILMDQLEQAISQPHKNQEYMQEIVQEMSQEQSLTERTQVQNQLQLQLIKHK 465

Query: 398  TDKKINKNEIAKLEMVIQSLNKDL---------VDKEYVISEKDTXXXXXXXXXXGKDTL 448
               K    ++   E++ Q +   L         + ++  +   D             D+L
Sbjct: 466  QVFKFILEDVCNSEVIKQQILNTLGQFKQFLLNIIQQQYLKSLDLMNNQKQDYSSQIDSL 525

Query: 449  IAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLK-QELNDEIKDVN-----VKDLI 502
            I +L   +QQ  E   +    TN ++  +  + + Q + Q L  +I ++N         +
Sbjct: 526  IQELNNVNQQLFE---MQKQNTNLQEQIQSKQDEHQYEMQNLQGQIDNLNSILEETNQNL 582

Query: 503  EKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFS-KVSDSNKEIVRLT 561
            EK    +  I    ++I      + + +   K + + +   I+  + K ++ N+   +L 
Sbjct: 583  EKDNQNQALIDHYQNQISQLETQLAQSQQQQKTQQQTLNTAIEQSNVKDAELNETKQKLN 642

Query: 562  EELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLES 621
                 L QK  +L+ +K   Q     YD  +++   + +   E+E L +T+ K   L  +
Sbjct: 643  SLNTLLKQKEEDLKMQKQLAQTKSTKYDQEKLLTQKLQQ---EIEAL-KTQNKQFQLDLN 698

Query: 622  QKFDL--VQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVH---------LEEQIDA 670
            ++ DL   Q+  + + K D  + K      LQ+ Q  ++IKS           L+EQ D 
Sbjct: 699  RQKDLNKQQQTDLGKLKADNQQLKQQSEQFLQTQQELTKIKSEFSKTLQEKNTLQEQFDE 758

Query: 671  LSASKKELALVIENLKLDKE---QLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKM 727
            +  S+  L  + + L+ +++   +L   + +L+ + E+   +++NY Q+N  L  +L+ +
Sbjct: 759  VKKSQALLTTLNDELQEEQQINDKLKQQLLELQLEFENSKEQMENYSQDNERLKQQLKDL 818

Query: 728  SAEKISELLAKINHEEQ--SKIQTQFGIDAKIQER-DLYI-ENIESELSKYKSRICRLEE 783
            + +    L      +EQ  SK Q    + ++ QE+ +L+  ++IE    K K      E 
Sbjct: 819  NNDYELTLQENQMLQEQIISKDQNLIQLQSQQQEQINLFCSQSIEQSDLKNKDLANSNES 878

Query: 784  SIAVMEDRRYSLERKADQLG---SYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQ 840
              + + D + SLE+  + +G   + +QE Q    +   +   L N++  L   ++ +++ 
Sbjct: 879  LQSQIYDLKLSLEQAQETIGQNQTSIQELQADSLKLKDENSTLKNQIQELSIKNQQIQES 938

Query: 841  L---LEI-EHENKELQKKNQILLEE---NQNLQISLSDMQQHYNALVEKANRTDLAESES 893
            L   + I +++ K +Q +   L +E   NQ   I L+++ + + AL ++    D   +E 
Sbjct: 939  LETQMSISQNQEKLIQNQTSQLEQEQVNNQRQGIQLTNLNKKFEALEQQLESKDQELNEY 998

Query: 894  TKYQTQLR----DLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEK 949
             +    L+      E  L + + E Q+   Q +   E + ++ N  +      +K L E 
Sbjct: 999  IQQTNYLKIKNEQSEQQLFKQSQELQSNKSQNQSSNESI-VQLNELVNHLREGEKQLQES 1057

Query: 950  YEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYIN 1009
             ++     +Q++ QL+E +  ++NL    +E   +N  L+ +   + QTQS         
Sbjct: 1058 VKEIQNQKSQIQKQLEEKEQLLQNLQ---QENKNLNAALLAEK-SENQTQSEQIRSLQNE 1113

Query: 1010 EINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSK 1069
             I K+N    + ++++    Q+ NN    Y   +S Y+ +     + L+  E+  Q    
Sbjct: 1114 LIQKINETTLENEKQLQLNIQQQNNKIQQYELQISKYKQQNENLNSNLQEAEKHKQLDKN 1173

Query: 1070 QLLDSKQHNEELQILVREQDDQIKELKETKLTFE-------MNIPKTEGMIISSTIEPMS 1122
            Q+ +  Q+ +ELQ  ++ Q  QI+E K+     +       + I + +  I S +++  S
Sbjct: 1174 QIAELNQNIQELQRNLQSQLSQIEESKQQNNQKDQQIQQLLLKIDEQKSQIESISLQLQS 1233

Query: 1123 DDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLN 1182
            +  N ++              ++++++ I  +  L++   K  +E ++   +I++LE   
Sbjct: 1234 EKKNLLEDNDVLKNANQQLQGLEQQQQTIIAQ--LKQDYEKKISEQKDLENQILKLEQNY 1291

Query: 1183 TELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQH 1242
               + +    Q  +NQ + + EQ   E  N L     L   + +   Q      E    +
Sbjct: 1292 QNESSNRQTIQNSLNQQREENEQNQQELKNRLIQNQSLIEEVDTLKQQHLLNQEE--NLN 1349

Query: 1243 LAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKI-VTMEQVTSLQNKLQD 1301
            L  +  D  + E  +R      E    Q +  + +  +E  N + +  +Q+  +Q    +
Sbjct: 1350 LQTQLKDLTQEEQNIRANARQQEQIQNQKIQELINENREAQNLVEILQKQIVQIQ---YE 1406

Query: 1302 KEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQ 1361
            KE+    L EK      Q++   +EIED+K  F                  +  +     
Sbjct: 1407 KEKIEEELSEKNL----QLDNYSNEIEDQKTQFLQKIEILQQNQQILEIQKKQTDNEILN 1462

Query: 1362 MQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTH 1421
             Q Q I  +N++N QL+                +   E ++ E   QL+LK+ EI ++  
Sbjct: 1463 YQNQ-IEKLNQDNLQLQNELKVLSSNIQKDIDSMK--EKQIAEKDAQLQLKNQEI-KELK 1518

Query: 1422 EYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESE 1481
            E  I L ++      ++ Q+ +  ++ +    E + +L  L + +++     +T ++E +
Sbjct: 1519 EKNIQLDEKMKLIGELQNQIRQTNEKFQ----ENQQKLQELEITINQLNQGIQTKEQECQ 1574

Query: 1482 IERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEIT 1541
             E +K   EL  ++  +   NK++    + L+EE+++ N      +N++    T+ DE+ 
Sbjct: 1575 -ESLKKSRELEDRLLVAQQENKKLISSVENLQEEISQKN------QNEQ----TIQDELK 1623

Query: 1542 NLQNMV-RASSSKI-QKHVSFASDTKQGRDEQLDNTMNKE 1579
              Q  V +    KI Q+    + +T+    EQ  + +N E
Sbjct: 1624 QFQQEVSKIKEEKILQESEIISKNTQLNLQEQKISQLNDE 1663



 Score =  155 bits (376), Expect = 1e-35
 Identities = 293/1513 (19%), Positives = 650/1513 (42%), Gaps = 144/1513 (9%)

Query: 90   ISESLANTLKQ-KEILMEKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTH-L 147
            I + + NTL Q K+ L+  I+Q        S  ++                +L +V   L
Sbjct: 481  IKQQILNTLGQFKQFLLNIIQQ----QYLKSLDLMNNQKQDYSSQIDSLIQELNNVNQQL 536

Query: 148  SNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXX 207
                K+  N    +Q K    +  + +LQ +I+  + I+E  N+                
Sbjct: 537  FEMQKQNTNLQEQIQSKQDEHQYEMQNLQGQIDNLNSILEETNQ--------NLEKDNQN 588

Query: 208  XXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEI 267
                +  + Q+++++      + + K ++Q L   IE  +V+ + L E  + L +    +
Sbjct: 589  QALIDHYQNQISQLETQLAQSQQQQKTQQQTLNTAIEQSNVKDAELNETKQKLNSLNTLL 648

Query: 268  SLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKK 327
              +   L  ++++              L  Q ++   E      ++  L++    +L K+
Sbjct: 649  KQKEEDL--KMQKQLAQTKSTKYDQEKLLTQKLQQEIEALKTQNKQFQLDLNRQKDLNKQ 706

Query: 328  IEL-LEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPW 386
             +  L  L    +Q  ++ E  L T    +K  S  SK    L  + + +    ++K   
Sbjct: 707  QQTDLGKLKADNQQLKQQSEQFLQTQQELTKIKSEFSKT---LQEKNTLQEQFDEVKK-- 761

Query: 387  SQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKD 446
            SQ    TLN +  ++   N+  K +++   L  +   ++     +D             D
Sbjct: 762  SQALLTTLNDELQEEQQINDKLKQQLLELQLEFENSKEQMENYSQDNERLKQQLKDLNND 821

Query: 447  TLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLK 506
                +L L+  Q ++   +I    N   +    + Q  L    + E  D+  KDL    +
Sbjct: 822  Y---ELTLQENQMLQ-EQIISKDQNLIQLQSQQQEQINLFCSQSIEQSDLKNKDLANSNE 877

Query: 507  SAEEQITQLNDEIDAA------NKNMIKVKSNHKLKLKQMQKTIDN-FSKVSDSNKEIVR 559
            S + QI  L   ++ A      N+  I+      LKLK    T+ N   ++S  N++I  
Sbjct: 878  SLQSQIYDLKLSLEQAQETIGQNQTSIQELQADSLKLKDENSTLKNQIQELSIKNQQIQE 937

Query: 560  LTEELHHLSQKVAEL-EEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISL 618
              E    +SQ   +L + +   L+   V+     +  +++ KK   +E   E++ + ++ 
Sbjct: 938  SLETQMSISQNQEKLIQNQTSQLEQEQVNNQRQGIQLTNLNKKFEALEQQLESKDQELN- 996

Query: 619  LESQKFDLVQELHILQQKYDEVEDKLADISQ-LQSDQVCSEIKS---VHLEEQIDALSAS 674
                  + +Q+ + L+ K ++ E +L   SQ LQS++  ++  +   V L E ++ L   
Sbjct: 997  ------EYIQQTNYLKIKNEQSEQQLFKQSQELQSNKSQNQSSNESIVQLNELVNHLREG 1050

Query: 675  KKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKL--EKMSAEKI 732
            +K+L   ++ ++  K Q+    K LE +KE ++  LQ   QEN +L   L  EK   +  
Sbjct: 1051 EKQLQESVKEIQNQKSQIQ---KQLE-EKEQLLQNLQ---QENKNLNAALLAEKSENQTQ 1103

Query: 733  SELLAKINHE-----EQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAV 787
            SE +  + +E      ++ ++ +  +   IQ+++  I+  E ++SKYK +   L  ++  
Sbjct: 1104 SEQIRSLQNELIQKINETTLENEKQLQLNIQQQNNKIQQYELQISKYKQQNENLNSNLQE 1163

Query: 788  MEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHE 847
             E  +   + +  +L   +QE Q+       Q +E   +       D+ +++ LL+I+ +
Sbjct: 1164 AEKHKQLDKNQIAELNQNIQELQRNLQSQLSQIEESKQQNN---QKDQQIQQLLLKIDEQ 1220

Query: 848  NKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNL 907
              +++  +  L  E +NL   L D     N +++ AN+    +    + QT +  L+ + 
Sbjct: 1221 KSQIESISLQLQSEKKNL---LED-----NDVLKNANQQ--LQGLEQQQQTIIAQLKQDY 1270

Query: 908  KRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRD--KKVLNEKYEKNIEYVTQLEAQLQ 965
            ++   E      QK  E + L++E N Q ES+ R   +  LN++ E+N +   +L+ +L 
Sbjct: 1271 EKKISE------QKDLENQILKLEQNYQNESSNRQTIQNSLNQQREENEQNQQELKNRLI 1324

Query: 966  EYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEI 1025
            + ++ IE     V+ L + +L L  +     QTQ  D T++  N    + A  +Q+++  
Sbjct: 1325 QNQSLIEE----VDTLKQQHL-LNQEENLNLQTQLKDLTQEEQN----IRANARQQEQIQ 1375

Query: 1026 IALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILV 1085
                Q++ N      ++V   + ++ Q   + E +EEE+   + QL     ++ E++   
Sbjct: 1376 NQKIQELINENREAQNLVEILQKQIVQIQYEKEKIEEELSEKNLQL---DNYSNEIEDQK 1432

Query: 1086 REQDDQIKELKETKLTFEMNIPKTEGMIIS--STIEPMSDDANNVDXXXXXXXXXXXXLK 1143
             +   +I+ L++ +   E+   +T+  I++  + IE ++ D   +               
Sbjct: 1433 TQFLQKIEILQQNQQILEIQKKQTDNEILNYQNQIEKLNQDNLQLQNELKVLSS-----N 1487

Query: 1144 VQEEEEFIQERSVLQEQSAKL---NTELQECYTKIIQLETLNTELTGHDVVNQEQINQLK 1200
            +Q++ + ++E+ +  E+ A+L   N E++E   K IQL+    +L G     Q QI Q  
Sbjct: 1488 IQKDIDSMKEKQIA-EKDAQLQLKNQEIKELKEKNIQLDE-KMKLIGE---LQNQIRQTN 1542

Query: 1201 SKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQ 1260
             K ++   +   L  T+ +L   I +             K+   Q      K   EL  +
Sbjct: 1543 EKFQENQQKLQELEITINQLNQGIQT-------------KEQECQESL---KKSRELEDR 1586

Query: 1261 LSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQI 1320
            L   + + ++L+ SV++  QEE ++    EQ  ++Q++L+  ++ +  ++E+   ++ + 
Sbjct: 1587 LLVAQQENKKLISSVEN-LQEEISQKNQNEQ--TIQDELKQFQQEVSKIKEE--KILQES 1641

Query: 1321 EILRSE----IEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINE--EN 1374
            EI+       ++++K++                 D+  + Q   ++Q+Q         +N
Sbjct: 1642 EIISKNTQLNLQEQKISQLNDEKDYLKTQMNEGKDMLKDLQQKLELQQQRQQKYEALVKN 1701

Query: 1375 AQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEF 1434
             +LK               +VN   +K+     ++E    +++    E+     Q+    
Sbjct: 1702 EELKYLQKIENLETELSSQQVN---SKL-----KIENAKRKLHSILIEFGKCKRQQQHST 1753

Query: 1435 ENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVK 1494
              ++ QLV++ K  + +  +   +L+++  ++ +   +++ +     ++ VK+  ++   
Sbjct: 1754 NFIKDQLVKFNKTYQTILVKLVKKLSVINSQIAQLKLNHQELDDMLRVQ-VKINPQIYKH 1812

Query: 1495 ITESVSLNKQVAE-LNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSK 1553
            + +     + V +   + +++ +++   M  A EN++ EI +L+ + ++L+N ++ ++ K
Sbjct: 1813 LNQLQQQQESVVKSFKEKIQQLMSQQENMLFADENRKQEIQSLSTDRSDLKNQLQETNQK 1872

Query: 1554 IQKHVSFASDTKQ 1566
            +Q+      + K+
Sbjct: 1873 LQQQQQINLELKE 1885



 Score =  154 bits (374), Expect = 2e-35
 Identities = 281/1418 (19%), Positives = 600/1418 (42%), Gaps = 131/1418 (9%)

Query: 216  QQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANK---LLEAARFEISLEHS 272
            QQ+ +  E F+  + E    K    K ++ K+      +E  K   LL     E+  E  
Sbjct: 719  QQLKQQSEQFLQTQQELTKIKSEFSKTLQEKNTLQEQFDEVKKSQALLTTLNDELQ-EEQ 777

Query: 273  KLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLE 332
            ++  +L+Q               +K+ +E   ++   ++++   ++ N  ELT  ++  +
Sbjct: 778  QINDKLKQQLLELQLEFEN----SKEQMENYSQDNERLKQQ-LKDLNNDYELT--LQENQ 830

Query: 333  HLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSE 392
             L  QI   ++ L    +    +     S S + S L      ++ A+  +S  SQ+   
Sbjct: 831  MLQEQIISKDQNLIQLQSQQQEQINLFCSQSIEQSDL----KNKDLANSNESLQSQIYDL 886

Query: 393  TLN-QDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQ 451
             L+ +   + I +N+ +  E+   SL   L D+   +  +                 I +
Sbjct: 887  KLSLEQAQETIGQNQTSIQELQADSLK--LKDENSTLKNQ-----------------IQE 927

Query: 452  LQLEHQQHMEG-PSLIHVGTNTEDVNEIAKVQEQLKQE-LNDEIKDVNVKDLIEKLKSAE 509
            L +++QQ  E   + + +  N E +  I     QL+QE +N++ + + + +L +K ++ E
Sbjct: 928  LSIKNQQIQESLETQMSISQNQEKL--IQNQTSQLEQEQVNNQRQGIQLTNLNKKFEALE 985

Query: 510  EQI----TQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELH 565
            +Q+     +LN+ I   N   IK + + +   KQ Q+   N S+   SN+ IV+L E ++
Sbjct: 986  QQLESKDQELNEYIQQTNYLKIKNEQSEQQLFKQSQELQSNKSQNQSSNESIVQLNELVN 1045

Query: 566  HLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLE-SQKF 624
            HL +   +L+E    +Q         ++ E +   + ++ EN     L A  L E S+  
Sbjct: 1046 HLREGEKQLQESVKEIQNQKSQIQK-QLEEKEQLLQNLQQEN---KNLNAALLAEKSENQ 1101

Query: 625  DLVQELHILQQKYDEV--EDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVI 682
               +++  LQ +  +   E  L +  QLQ +      K    E QI       + L   +
Sbjct: 1102 TQSEQIRSLQNELIQKINETTLENEKQLQLNIQQQNNKIQQYELQISKYKQQNENLNSNL 1161

Query: 683  ENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHE 742
            +  +  K+     I +L  + +++   LQ+ + + ++ + +      ++I +LL KI+ E
Sbjct: 1162 QEAEKHKQLDKNQIAELNQNIQELQRNLQSQLSQ-IEESKQQNNQKDQQIQQLLLKID-E 1219

Query: 743  EQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLE-ESIAVMEDRRYSLERKADQ 801
            ++S+I++   +  + ++++L  +N    L     ++  LE +   ++   +   E+K  +
Sbjct: 1220 QKSQIES-ISLQLQSEKKNLLEDN--DVLKNANQQLQGLEQQQQTIIAQLKQDYEKKISE 1276

Query: 802  ---LGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQK----- 853
               L + + + ++ Y   +     + N L    + +   +++L     +N+ L +     
Sbjct: 1277 QKDLENQILKLEQNYQNESSNRQTIQNSLNQQREENEQNQQELKNRLIQNQSLIEEVDTL 1336

Query: 854  KNQILL--EENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRIT 911
            K Q LL  EEN NLQ  L D+ Q    +   A + +  +++  +          NL  I 
Sbjct: 1337 KQQHLLNQEENLNLQTQLKDLTQEEQNIRANARQQEQIQNQKIQELINENREAQNLVEIL 1396

Query: 912  HEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQ----LEAQLQEY 967
             +    I  +K++IE+   E N Q+++   + +    ++ + IE + Q    LE Q ++ 
Sbjct: 1397 QKQIVQIQYEKEKIEEELSEKNLQLDNYSNEIEDQKTQFLQKIEILQQNQQILEIQKKQT 1456

Query: 968  KNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIA 1027
             N I N    +E+LN+ NL+L ++          D       +I + +A L+ K++EI  
Sbjct: 1457 DNEILNYQNQIEKLNQDNLQLQNELKVLSSNIQKDIDSMKEKQIAEKDAQLQLKNQEIKE 1516

Query: 1028 LNQKINNAQV-SYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVR 1086
            L +K  N Q+   M ++ + ++++ Q   K +  ++++Q +    +   Q N+ +Q   +
Sbjct: 1517 LKEK--NIQLDEKMKLIGELQNQIRQTNEKFQENQQKLQELE---ITINQLNQGIQ--TK 1569

Query: 1087 EQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQE 1146
            EQ+ Q    K  +L   + + + E   + S++E + ++ +  +             + Q+
Sbjct: 1570 EQECQESLKKSRELEDRLLVAQQENKKLISSVENLQEEISQKNQNEQTIQDELK--QFQQ 1627

Query: 1147 EEEFIQERSVLQE-QSAKLNTELQECYTKIIQL----ETLNTELT-GHDVVN--QEQI-- 1196
            E   I+E  +LQE +    NT+L     KI QL    + L T++  G D++   Q+++  
Sbjct: 1628 EVSKIKEEKILQESEIISKNTQLNLQEQKISQLNDEKDYLKTQMNEGKDMLKDLQQKLEL 1687

Query: 1197 -NQLKSKLEQL-NTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTE 1254
              Q + K E L   E    L  +  L + +SS       +I E  K+ L     +F K +
Sbjct: 1688 QQQRQQKYEALVKNEELKYLQKIENLETELSSQQVNSKLKI-ENAKRKLHSILIEFGKCK 1746

Query: 1255 HE-------LRVQLSAFESKYEQLLDSVQSSTQEETNKIV-------TMEQVTSLQNKLQ 1300
             +       ++ QL  F   Y+ +L  +        ++I         ++ +  +Q K+ 
Sbjct: 1747 RQQQHSTNFIKDQLVKFNKTYQTILVKLVKKLSVINSQIAQLKLNHQELDDMLRVQVKIN 1806

Query: 1301 DK-EEHLRNLQEKYADVINQI--EILRSEIEDEKVAFX-XXXXXXXXXXXXXXXDLRTEN 1356
             +  +HL  LQ++   V+     +I +   + E + F                 DL+ + 
Sbjct: 1807 PQIYKHLNQLQQQQESVVKSFKEKIQQLMSQQENMLFADENRKQEIQSLSTDRSDLKNQL 1866

Query: 1357 QSYK---QMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAK----------VL 1403
            Q      Q Q+Q  L + EE  +L+  +             ++    K          + 
Sbjct: 1867 QETNQKLQQQQQINLELKEEIQRLESQNLLYQGQIQEKNSAIDQQNEKCKLIPNLKNEIQ 1926

Query: 1404 ELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQ----LVEYEKRIEDLTYE-KESE 1458
            +L  Q + + + I +    + +T+  + ++ +++++Q    L   E + +D+  + ++ E
Sbjct: 1927 QLEQQRQRQQTMINEIQASFQVTIDHQQEQIQSLKEQNRDLLSGQEIKTQDIYLKLQKLE 1986

Query: 1459 LAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAK 1518
              +++ K        +   K+ EI++++L +  N  ++E  +L     +LN  +E    +
Sbjct: 1987 QQLIKEKQFSQQIFDKLSSKDEEIQQLQLAQRKN--LSEIDNLTNINEDLNDKIENLKDQ 2044

Query: 1519 TNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQK 1556
            T   Q     +E  I  L + + N    +     K+ +
Sbjct: 2045 TQRFQVYFSEKEETIRNLKETVYNQNLQLEEKGKKLNQ 2082



 Score =  140 bits (339), Expect = 3e-31
 Identities = 251/1394 (18%), Positives = 584/1394 (41%), Gaps = 108/1394 (7%)

Query: 147  LSNTIKEKDNALSVLQVKMKIMETTILDLQ-EKINEKDQIIEAKNKATTXXXXXXXXXXX 205
            L  ++KE  N  S +Q +++  E  + +LQ E  N    ++  K++  T           
Sbjct: 1054 LQESVKEIQNQKSQIQKQLEEKEQLLQNLQQENKNLNAALLAEKSENQTQSEQIRSLQNE 1113

Query: 206  XXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARF 265
                  E T +   ++Q N      + +  + ++ K  +  +   S+L+EA K  +  + 
Sbjct: 1114 LIQKINETTLENEKQLQLNIQQQNNKIQQYELQISKYKQQNENLNSNLQEAEKHKQLDKN 1173

Query: 266  EISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEE-KGSLEIANMTEL 324
            +I+ E ++  QEL++                 Q  +   +   +I+E K  +E  ++   
Sbjct: 1174 QIA-ELNQNIQELQRNLQSQLSQIEESKQQNNQKDQQIQQLLLKIDEQKSQIESISLQLQ 1232

Query: 325  TKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKS 384
            ++K  LLE  N  ++  N++L+       T    +    +K   +  +K   N   K++ 
Sbjct: 1233 SEKKNLLED-NDVLKNANQQLQGLEQQQQTIIAQLKQDYEK--KISEQKDLENQILKLEQ 1289

Query: 385  PWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXG 444
             +   SS   N+ T +     +  + E   Q L   L+  + +I E DT           
Sbjct: 1290 NYQNESS---NRQTIQNSLNQQREENEQNQQELKNRLIQNQSLIEEVDTLKQQHLLNQ-- 1344

Query: 445  KDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDE-IKDVNVKDLIE 503
            ++ L  Q QL+     E    I      ++  +  K+QE + +    + + ++  K +++
Sbjct: 1345 EENLNLQTQLKDLTQEE--QNIRANARQQEQIQNQKIQELINENREAQNLVEILQKQIVQ 1402

Query: 504  ---KLKSAEEQITQLNDEIDAANKNMIKVKSN--HKLKLKQMQKTIDNFSKVSDSNKEIV 558
               + +  EE++++ N ++D  +  +   K+    K+++ Q  + I    K    N EI+
Sbjct: 1403 IQYEKEKIEEELSEKNLQLDNYSNEIEDQKTQFLQKIEILQQNQQILEIQKKQTDN-EIL 1461

Query: 559  RLTEELHHLSQKVAELEEE----KGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLK 614
                ++  L+Q   +L+ E      N+Q  +      ++ E D   ++   E + E + K
Sbjct: 1462 NYQNQIEKLNQDNLQLQNELKVLSSNIQKDIDSMKEKQIAEKDAQLQLKNQE-IKELKEK 1520

Query: 615  AISLLESQKF--DLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALS 672
             I L E  K   +L  ++    +K+ E + KL ++ ++  +Q+   I++   E Q ++L 
Sbjct: 1521 NIQLDEKMKLIGELQNQIRQTNEKFQENQQKLQEL-EITINQLNQGIQTKEQECQ-ESLK 1578

Query: 673  ASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNY--IQENM-DLTDKLEKMSA 729
             S++    + + L + +++    I  +EN +E+I  K QN   IQ+ +     ++ K+  
Sbjct: 1579 KSRE----LEDRLLVAQQENKKLISSVENLQEEISQKNQNEQTIQDELKQFQQEVSKIKE 1634

Query: 730  EKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVME 789
            EKI +    I+   Q  +Q Q     KI + +   + +++++++ K  +  L++ + + +
Sbjct: 1635 EKILQESEIISKNTQLNLQEQ-----KISQLNDEKDYLKTQMNEGKDMLKDLQQKLELQQ 1689

Query: 790  DRRYSLER--KADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHE 847
             R+   E   K ++L  YLQ+ +   +E + Q+   VN    + +  R +   L+E    
Sbjct: 1690 QRQQKYEALVKNEEL-KYLQKIENLETELSSQQ---VNSKLKIENAKRKLHSILIEFGKC 1745

Query: 848  NKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNL 907
             ++ Q     +  ++Q ++ +    + +   LV+   +  +  S+  + +   ++L+  L
Sbjct: 1746 KRQQQHSTNFI--KDQLVKFN----KTYQTILVKLVKKLSVINSQIAQLKLNHQELDDML 1799

Query: 908  K---RITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQL 964
            +   +I  +    + Q +++ E +   F  +I+  +  ++ +    E   + +  L    
Sbjct: 1800 RVQVKINPQIYKHLNQLQQQQESVVKSFKEKIQQLMSQQENMLFADENRKQEIQSLSTDR 1859

Query: 965  QEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQY------INEINKLNALL 1018
             + KN ++  N  +++  ++NLEL ++ +Q+ ++Q+  Y  Q       I++ N+   L+
Sbjct: 1860 SDLKNQLQETNQKLQQQQQINLELKEE-IQRLESQNLLYQGQIQEKNSAIDQQNEKCKLI 1918

Query: 1019 KQKDEEIIALNQK-------INNAQVSYMSMVSDYESKLAQFTT-----------KLENM 1060
                 EI  L Q+       IN  Q S+   +   + ++                K +++
Sbjct: 1919 PNLKNEIQQLEQQRQRQQTMINEIQASFQVTIDHQQEQIQSLKEQNRDLLSGQEIKTQDI 1978

Query: 1061 EEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEP 1120
              ++Q++ +QL+  KQ ++++   +  +D++I++L+   L    N+ + + +  ++  E 
Sbjct: 1979 YLKLQKLEQQLIKEKQFSQQIFDKLSSKDEEIQQLQ---LAQRKNLSEIDNL--TNINED 2033

Query: 1121 MSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLET 1180
            ++D   N+             +   E+EE I+    L+E     N +L+E   K+ QL+ 
Sbjct: 2034 LNDKIENLKDQTQRFQ-----VYFSEKEETIRN---LKETVYNQNLQLEEKGKKLNQLQN 2085

Query: 1181 LNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWK 1240
             N  L       +EQ+ +   K ++ N   + +   + +    IS  +        E   
Sbjct: 2086 DNEVLRKKYKDQEEQMMKNDIKFQRQNNRMEQIQKLIKDY-PKISKEIGDTIKNTEEFCL 2144

Query: 1241 QHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTM-EQVTSLQNKL 1299
            + L      F K    L+ ++   E+  EQ +  ++   Q++  +   M  Q  ++ N+ 
Sbjct: 2145 EKLRFLTQLFMKKIQTLQEKIEESETANEQEIQKLKKQLQQQQQQYDEMFSQTLTINNEN 2204

Query: 1300 QDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSY 1359
             D   H +++ +   + I++ +  + E++ +K  F                      Q +
Sbjct: 2205 PDMMTHFKDVLK---NAISERDQFQQELKQKKEQFDNASVENNYLKLQVQNLKDQLEQKW 2261

Query: 1360 KQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVL--------ELTHQLEL 1411
             +   QS+   + +N +++K               V     K          +L  QL+ 
Sbjct: 2262 NESANQSLDLSSIDNQEIRKFEHSSINNATIIDPTVQSGHTKSSLQIKEFQNQLAQQLQQ 2321

Query: 1412 KDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENAN 1471
            ++     K ++  + +     E E  +  L++Y++  E    +  S+L     ++ +  N
Sbjct: 2322 QNENNNTKFYDLQLEIDSYKQEIEKYKMNLIDYQQE-EQKMVKMISDLKRENYQLSQTIN 2380

Query: 1472 HYETMQKESEIERV 1485
              +T   + +I+++
Sbjct: 2381 QTDTKSLKQQIKQL 2394



 Score =  138 bits (333), Expect = 2e-30
 Identities = 299/1520 (19%), Positives = 634/1520 (41%), Gaps = 145/1520 (9%)

Query: 164  KMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQE 223
            K KI+ ++ +++Q+   +  Q++E  N                      ++K Q  K   
Sbjct: 40   KPKILSSSQIEMQQLAEKNKQLVEDLNFLNLSFKELKLGTDEL------NSKNQSLKKHI 93

Query: 224  NFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELE---Q 280
              +    + K+++   LK    K      +EE NK  E +  + ++   K  Q LE   +
Sbjct: 94   KELLQTLKHKEDE---LKKAREKQKNGEQIEE-NKTQEKSVIDYAIYMEKQFQTLEDKVK 149

Query: 281  XXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIE-LLEHLNCQIR 339
                          LAK+  E     +  I+EK +++     E+  +I+     L  Q++
Sbjct: 150  KYKKLLEKNGYDDQLAKKVEEQKKSIQQLIQEKETIK-REKEEIQNQIQNQRSDLEPQLK 208

Query: 340  QTNKELENKLATMGTESKAVSSPSKK-GSPLISRKSGRNTASKMKSPWSQLSSETLNQ-- 396
              N++L+N       E +  +S  +K  + LI     +   ++ KS    L S    Q  
Sbjct: 209  ILNEQLQNSEQLHIQEIQLKNSMIEKLNNQLIKLMDNQKQLNESKSHNQILQSRITEQER 268

Query: 397  ---DTDKKINKNEIAKLEMV--IQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQ 451
               D D++        LE    IQ LNK++   +  +++++            K+    Q
Sbjct: 269  KYKDLDEQAKHVNGTALEYSKQIQQLNKEIQTYKQQLAQQEEQCNRIVQQKQ-KEINQVQ 327

Query: 452  LQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQE---LNDEIKDVNVKDLIEKLKSA 508
             QLE Q+H+E  +L     N +   ++ +    L+ +   L DE   +  K   + LK+ 
Sbjct: 328  SQLE-QKHLE-ETLKKQQQNEQQYLQVIEQFNSLQNKIALLEDENSSLKQKSF-KTLKNV 384

Query: 509  EEQITQLNDEID----AANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVR----- 559
             +++ ++  E+       + ++ ++    ++ + Q+++ I    K  +  +EIV+     
Sbjct: 385  VQELKRMKLELQNLKMMGHYDISQLNGLEQILMDQLEQAISQPHKNQEYMQEIVQEMSQE 444

Query: 560  --LTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYK-----KMIEMENLAETR 612
              LTE     +Q   +L + K   +  L D  +  +I+  +       K   +  + +  
Sbjct: 445  QSLTERTQVQNQLQLQLIKHKQVFKFILEDVCNSEVIKQQILNTLGQFKQFLLNIIQQQY 504

Query: 613  LKAISLLESQKFD-------LVQELHILQQKYDEVEDKLADIS-QLQSDQVCSEIKSVHL 664
            LK++ L+ +QK D       L+QEL+ + Q+  E++ +  ++  Q+QS Q   + +  +L
Sbjct: 505  LKSLDLMNNQKQDYSSQIDSLIQELNNVNQQLFEMQKQNTNLQEQIQSKQDEHQYEMQNL 564

Query: 665  EEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKL------QNYIQENM 718
            + QID L++  +E     +NL+ D +     I   +N    +  +L      Q   Q+ +
Sbjct: 565  QGQIDNLNSILEETN---QNLEKDNQN-QALIDHYQNQISQLETQLAQSQQQQKTQQQTL 620

Query: 719  DLTDKLEKMSAEKISELLAKINH--------EEQSKIQTQFGI--DAKIQERDLYIENIE 768
            +   +   +   +++E   K+N         EE  K+Q Q       K  +  L  + ++
Sbjct: 621  NTAIEQSNVKDAELNETKQKLNSLNTLLKQKEEDLKMQKQLAQTKSTKYDQEKLLTQKLQ 680

Query: 769  SELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELV---N 825
             E+   K++  + +  +   +D     +    +L +  Q+ ++   ++   + EL    +
Sbjct: 681  QEIEALKTQNKQFQLDLNRQKDLNKQQQTDLGKLKADNQQLKQQSEQFLQTQQELTKIKS 740

Query: 826  RLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEE---NQNLQISLSDMQQHYNALVEK 882
              +  +     +++Q  E++     L   N  L EE   N  L+  L ++Q  +    E+
Sbjct: 741  EFSKTLQEKNTLQEQFDEVKKSQALLTTLNDELQEEQQINDKLKQQLLELQLEFENSKEQ 800

Query: 883  ANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRD 942
                     ++ + + QL+DL ++ +    E+Q L  Q   + ++L      Q++S  + 
Sbjct: 801  MENYS---QDNERLKQQLKDLNNDYELTLQENQMLQEQIISKDQNL-----IQLQS--QQ 850

Query: 943  KKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPD 1002
            ++ +N    ++IE   Q + + ++  N+ E+L   + +L K++LE   + + + QT   +
Sbjct: 851  QEQINLFCSQSIE---QSDLKNKDLANSNESLQSQIYDL-KLSLEQAQETIGQNQTSIQE 906

Query: 1003 YTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEE 1062
                 + ++   N+ LK + +E+   NQ+I  +  + MS+  + E  +   T++LE  + 
Sbjct: 907  LQADSL-KLKDENSTLKNQIQELSIKNQQIQESLETQMSISQNQEKLIQNQTSQLEQEQV 965

Query: 1063 EMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMS 1122
              QR   QL +  +  E L+  +  +D ++ E  +     ++   ++E  +   + E  S
Sbjct: 966  NNQRQGIQLTNLNKKFEALEQQLESKDQELNEYIQQTNYLKIKNEQSEQQLFKQSQELQS 1025

Query: 1123 DDANNVDXXXXXXXXXXXXLKVQEEEEFIQER-SVLQEQSAKLNTELQECYTKIIQLE-- 1179
            + + N                ++E E+ +QE    +Q Q +++  +L+E    +  L+  
Sbjct: 1026 NKSQNQSSNESIVQLNELVNHLREGEKQLQESVKEIQNQKSQIQKQLEEKEQLLQNLQQE 1085

Query: 1180 --TLNTELTGHDVVNQEQINQLKSKLEQLNTE-NDNLLSTVAELRSSI---SSAVDQRGF 1233
               LN  L      NQ Q  Q++S   +L  + N+  L    +L+ +I   ++ + Q   
Sbjct: 1086 NKNLNAALLAEKSENQTQSEQIRSLQNELIQKINETTLENEKQLQLNIQQQNNKIQQYEL 1145

Query: 1234 EIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVT 1293
            +I++ +KQ      ++ Q+ E   ++  +   ++  Q +  +Q + Q + ++I   +Q  
Sbjct: 1146 QISK-YKQQNENLNSNLQEAEKHKQLDKNQI-AELNQNIQELQRNLQSQLSQIEESKQ-- 1201

Query: 1294 SLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLR 1353
              QN    K++ ++ L  K  +  +QIE +  +++ EK                     +
Sbjct: 1202 --QNN--QKDQQIQQLLLKIDEQKSQIESISLQLQSEKKNLLEDNDVLKNANQQLQGLEQ 1257

Query: 1354 TENQSYKQMQEQSILNINE----ENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQL 1409
             +     Q+++     I+E    EN  LK               + +  + +     +Q 
Sbjct: 1258 QQQTIIAQLKQDYEKKISEQKDLENQILKLEQNYQNESSNRQTIQNSLNQQREENEQNQQ 1317

Query: 1410 ELKDSEIY-QKTHEYTITLTQRN----DEFENVRQQLVEYEKRIEDLTYEKESELAILRL 1464
            ELK+  I  Q   E   TL Q++    +E  N++ QL +  +  +++      +  I   
Sbjct: 1318 ELKNRLIQNQSLIEEVDTLKQQHLLNQEENLNLQTQLKDLTQEEQNIRANARQQEQIQNQ 1377

Query: 1465 KMHENANH-------YETMQKES---EIERVKLIEELNVKITE----SVSLNKQVAELNK 1510
            K+ E  N         E +QK+    + E+ K+ EEL+ K  +    S  +  Q  +  +
Sbjct: 1378 KIQELINENREAQNLVEILQKQIVQIQYEKEKIEEELSEKNLQLDNYSNEIEDQKTQFLQ 1437

Query: 1511 ALE-----EEVAKTNEMQTALE--NQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASD 1563
             +E     +++ +  + QT  E  N + +I  LN +   LQN ++  SS IQK +    +
Sbjct: 1438 KIEILQQNQQILEIQKKQTDNEILNYQNQIEKLNQDNLQLQNELKVLSSNIQKDIDSMKE 1497

Query: 1564 TKQGRDE---QLDNTMNKEL 1580
             +    +   QL N   KEL
Sbjct: 1498 KQIAEKDAQLQLKNQEIKEL 1517



 Score =  133 bits (321), Expect = 4e-29
 Identities = 213/1157 (18%), Positives = 496/1157 (42%), Gaps = 78/1157 (6%)

Query: 480  KVQEQLK--QELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNH---- 533
            KV+EQ K  Q+L  E K+   ++  E     + Q + L  ++   N+ +   +  H    
Sbjct: 167  KVEEQKKSIQQLIQE-KETIKREKEEIQNQIQNQRSDLEPQLKILNEQLQNSEQLHIQEI 225

Query: 534  KLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRM 593
            +LK   ++K  +   K+ D+ K++         L  ++ E E +  +L      + +G  
Sbjct: 226  QLKNSMIEKLNNQLIKLMDNQKQLNESKSHNQILQSRITEQERKYKDLD-EQAKHVNGTA 284

Query: 594  IESDVYKKMIEMENLA-ETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLAD--ISQL 650
            +E   Y K I+  N   +T  + ++  E Q   +VQ+    Q++ ++V+ +L    + + 
Sbjct: 285  LE---YSKQIQQLNKEIQTYKQQLAQQEEQCNRIVQQK---QKEINQVQSQLEQKHLEET 338

Query: 651  QSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKL 710
               Q  +E + + + EQ ++L    K   L  EN  L K++ + T+K++  + + +  +L
Sbjct: 339  LKKQQQNEQQYLQVIEQFNSLQ--NKIALLEDENSSL-KQKSFKTLKNVVQELKRMKLEL 395

Query: 711  QNY-IQENMDLT--DKLEKMSAEKISELLAKI--NHEEQSKIQTQFGIDAKIQERDLYIE 765
            QN  +  + D++  + LE++  +++ + +++   N E   +I  +   +  + ER     
Sbjct: 396  QNLKMMGHYDISQLNGLEQILMDQLEQAISQPHKNQEYMQEIVQEMSQEQSLTERTQVQN 455

Query: 766  NIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVN 825
             ++ +L K+K     + E +   E  +  +    + LG + Q       +  ++  +L+N
Sbjct: 456  QLQLQLIKHKQVFKFILEDVCNSEVIKQQI---LNTLGQFKQFLLNIIQQQYLKSLDLMN 512

Query: 826  RLAVLMDHDRVVEKQLLEIEHENK---ELQKKNQILLEENQNLQISLSDMQQHYNALVEK 882
                  D+   ++  + E+ + N+   E+QK+N  L E+ Q+ Q       Q+    ++ 
Sbjct: 513  NQK--QDYSSQIDSLIQELNNVNQQLFEMQKQNTNLQEQIQSKQDEHQYEMQNLQGQIDN 570

Query: 883  ANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIE-SAIR 941
             N      +++ +   Q + L  + +    + +T + Q +++ +  +   NT IE S ++
Sbjct: 571  LNSILEETNQNLEKDNQNQALIDHYQNQISQLETQLAQSQQQQKTQQQTLNTAIEQSNVK 630

Query: 942  DKKVLNEKYEKNIEYVTQLEAQLQEYK--NNIENLNMNVEELNKMNLELIDKHVQKQQTQ 999
            D + LNE  +K     T L+ + ++ K    +        +  K+  + + + ++  +TQ
Sbjct: 631  DAE-LNETKQKLNSLNTLLKQKEEDLKMQKQLAQTKSTKYDQEKLLTQKLQQEIEALKTQ 689

Query: 1000 SPDYTEQYINEINKLNALLKQKDEEIIAL---NQKINNAQVSYMSMVSDYESKLAQFTTK 1056
            +    +Q+  ++N+   L KQ+  ++  L   NQ++      ++    +     ++F+  
Sbjct: 690  N----KQFQLDLNRQKDLNKQQQTDLGKLKADNQQLKQQSEQFLQTQQELTKIKSEFSKT 745

Query: 1057 LE---NMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMI 1113
            L+    ++E+   V K        N+ELQ   +  D   ++L E +L FE +  + E   
Sbjct: 746  LQEKNTLQEQFDEVKKSQALLTTLNDELQEEQQINDKLKQQLLELQLEFENSKEQMENYS 805

Query: 1114 -ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECY 1172
              +  ++    D NN                + +++  IQ +S  QEQ   +N     C 
Sbjct: 806  QDNERLKQQLKDLNNDYELTLQENQMLQEQIISKDQNLIQLQSQQQEQ---INL---FCS 859

Query: 1173 TKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRG 1232
              I Q +  N +L   +   Q QI  LK  LEQ         +++ EL++      D+  
Sbjct: 860  QSIEQSDLKNKDLANSNESLQSQIYDLKLSLEQAQETIGQNQTSIQELQADSLKLKDEN- 918

Query: 1233 FEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQV 1292
                   K  + +     Q+ +  L  Q+S  +++ + + +      QE+ N      Q+
Sbjct: 919  ----STLKNQIQELSIKNQQIQESLETQMSISQNQEKLIQNQTSQLEQEQVNNQRQGIQL 974

Query: 1293 TSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDL 1352
            T+L  K +  E+ L +  ++  + I Q   L+ + E  +                     
Sbjct: 975  TNLNKKFEALEQQLESKDQELNEYIQQTNYLKIKNEQSEQQLFKQSQELQSNKSQN---- 1030

Query: 1353 RTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQ-LEL 1411
            ++ N+S  Q+ E  + ++ E   QL++S             ++ + E  +  L  +   L
Sbjct: 1031 QSSNESIVQLNE-LVNHLREGEKQLQESVKEIQNQKSQIQKQLEEKEQLLQNLQQENKNL 1089

Query: 1412 KDSEIYQKTHEYTIT---LTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHE 1468
              + + +K+   T +    + +N+  + + +  +E EK+++    ++ +++    L++ +
Sbjct: 1090 NAALLAEKSENQTQSEQIRSLQNELIQKINETTLENEKQLQLNIQQQNNKIQQYELQISK 1149

Query: 1469 NANHYETMQKE-SEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALE 1527
                 E +     E E+ K +++      +   LN+ + EL + L+ ++++  E +    
Sbjct: 1150 YKQQNENLNSNLQEAEKHKQLDK-----NQIAELNQNIQELQRNLQSQLSQIEESKQQNN 1204

Query: 1528 NQEIEIVTLNDEITNLQNMVRASSSKIQ---KHVSFASDTKQGRDEQLDNTMNKELLDAV 1584
             ++ +I  L  +I   ++ + + S ++Q   K++   +D  +  ++QL   + ++    +
Sbjct: 1205 QKDQQIQQLLLKIDEQKSQIESISLQLQSEKKNLLEDNDVLKNANQQLQG-LEQQQQTII 1263

Query: 1585 PRAELDLAMYMLHQRDV 1601
             + + D    +  Q+D+
Sbjct: 1264 AQLKQDYEKKISEQKDL 1280



 Score =  132 bits (318), Expect = 1e-28
 Identities = 231/1158 (19%), Positives = 479/1158 (41%), Gaps = 108/1158 (9%)

Query: 502  IEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVR-- 559
            + KL +  E +   N E+ +  ++  K +     K K +  +     ++++ NK++V   
Sbjct: 6    LHKLNNLLETVNLRNQELLSQLQSDYKSRETSPPKPKILSSSQIEMQQLAEKNKQLVEDL 65

Query: 560  --LTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAIS 617
              L      L     EL  +  +L+ H+ +       + D  KK  E +   E     I 
Sbjct: 66   NFLNLSFKELKLGTDELNSKNQSLKKHIKELLQTLKHKEDELKKAREKQKNGEQ----IE 121

Query: 618  LLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKE 677
              ++Q+  ++     +++++  +EDK+    +L       +  +  +EEQ      S ++
Sbjct: 122  ENKTQEKSVIDYAIYMEKQFQTLEDKVKKYKKLLEKNGYDDQLAKKVEEQ----KKSIQQ 177

Query: 678  LALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLA 737
            L    E +K +KE++   I   +N + D+  +L+  + E +  +++L     +  + ++ 
Sbjct: 178  LIQEKETIKREKEEIQNQI---QNQRSDLEPQLK-ILNEQLQNSEQLHIQEIQLKNSMIE 233

Query: 738  KINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLER 797
            K+N++    +  Q  ++       +    I  +  KYK     L+E    +        +
Sbjct: 234  KLNNQLIKLMDNQKQLNESKSHNQILQSRITEQERKYKD----LDEQAKHVNGTALEYSK 289

Query: 798  KADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQI 857
            +  QL   +Q     Y +   Q++E  NR+      +    +  LE +H  + L+K+ Q 
Sbjct: 290  QIQQLNKEIQ----TYKQQLAQQEEQCNRIVQQKQKEINQVQSQLEQKHLEETLKKQQQ- 344

Query: 858  LLEENQNLQISLSDMQQHYNALVEK-ANRTDLAESESTKYQTQLRDLESNLKRITHEHQT 916
               E Q LQ+      + +N+L  K A   D   S   K    L+++   LKR+  E Q 
Sbjct: 345  --NEQQYLQVI-----EQFNSLQNKIALLEDENSSLKQKSFKTLKNVVQELKRMKLELQN 397

Query: 917  LIVQKKKEIED---LEIEFNTQIESAI----RDKKVLNE-----KYEKNIEYVTQLEAQL 964
            L +    +I     LE     Q+E AI    ++++ + E       E+++   TQ++ QL
Sbjct: 398  LKMMGHYDISQLNGLEQILMDQLEQAISQPHKNQEYMQEIVQEMSQEQSLTERTQVQNQL 457

Query: 965  Q----EYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQ 1020
            Q    ++K   + +  +V     +  ++++   Q +Q       +QY+  ++ +N   + 
Sbjct: 458  QLQLIKHKQVFKFILEDVCNSEVIKQQILNTLGQFKQFLLNIIQQQYLKSLDLMNNQKQD 517

Query: 1021 KDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQL--LDS--KQ 1076
               +I +L Q++NN       M     +   Q  +K +  + EMQ +  Q+  L+S  ++
Sbjct: 518  YSSQIDSLIQELNNVNQQLFEMQKQNTNLQEQIQSKQDEHQYEMQNLQGQIDNLNSILEE 577

Query: 1077 HNEEL------QILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDX 1130
             N+ L      Q L+    +QI +L ET+L       KT+   +++ IE  +     ++ 
Sbjct: 578  TNQNLEKDNQNQALIDHYQNQISQL-ETQLAQSQQQQKTQQQTLNTAIEQSNVKDAELNE 636

Query: 1131 XXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTE---LQECYTKIIQLETLN----T 1183
                       LK Q+EE+   ++ + Q +S K + E    Q+   +I  L+T N     
Sbjct: 637  TKQKLNSLNTLLK-QKEEDLKMQKQLAQTKSTKYDQEKLLTQKLQQEIEALKTQNKQFQL 695

Query: 1184 ELTGHDVVNQEQ---INQLKSKLEQLNTENDNLLSTVAEL---RSSISSAVDQRGF---E 1234
            +L     +N++Q   + +LK+  +QL  +++  L T  EL   +S  S  + ++     +
Sbjct: 696  DLNRQKDLNKQQQTDLGKLKADNQQLKQQSEQFLQTQQELTKIKSEFSKTLQEKNTLQEQ 755

Query: 1235 IAELWKQH-----LAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTM 1289
              E+ K       L     + Q+   +L+ QL   + ++E   + +++ +Q+        
Sbjct: 756  FDEVKKSQALLTTLNDELQEEQQINDKLKQQLLELQLEFENSKEQMENYSQDNER---LK 812

Query: 1290 EQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXX 1349
            +Q+  L N  +   +  + LQE+       +  L+S+ +++   F               
Sbjct: 813  QQLKDLNNDYELTLQENQMLQEQIISKDQNLIQLQSQQQEQINLF---CSQSIEQSDLKN 869

Query: 1350 XDLRTENQSYKQM---------QEQSILNINEENAQ-LKKSSXXXXXXXXXXXXRVNDAE 1399
             DL   N+S +           Q Q  +  N+ + Q L+  S            ++ +  
Sbjct: 870  KDLANSNESLQSQIYDLKLSLEQAQETIGQNQTSIQELQADSLKLKDENSTLKNQIQELS 929

Query: 1400 AKVLELTHQLELKDSEIYQKTHEYTITLTQR--NDEFENVRQ--QLVEYEKRIEDLTYEK 1455
             K  ++   LE + S I Q   +     T +   ++  N RQ  QL    K+ E L  + 
Sbjct: 930  IKNQQIQESLETQMS-ISQNQEKLIQNQTSQLEQEQVNNQRQGIQLTNLNKKFEALEQQL 988

Query: 1456 ESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKA---L 1512
            ES+   L  +  +  N+ +   ++SE +  K  +EL    +++ S N+ + +LN+    L
Sbjct: 989  ESKDQELN-EYIQQTNYLKIKNEQSEQQLFKQSQELQSNKSQNQSSNESIVQLNELVNHL 1047

Query: 1513 EEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQL 1572
             E   +  E    ++NQ+ +I    +E   L   ++  +  +   +       Q + EQ+
Sbjct: 1048 REGEKQLQESVKEIQNQKSQIQKQLEEKEQLLQNLQQENKNLNAALLAEKSENQTQSEQI 1107

Query: 1573 DNTMNKELLDAVPRAELD 1590
             +  N EL+  +    L+
Sbjct: 1108 RSLQN-ELIQKINETTLE 1124



 Score =  124 bits (298), Expect = 3e-26
 Identities = 217/1114 (19%), Positives = 471/1114 (42%), Gaps = 85/1114 (7%)

Query: 237  QRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLA 296
            Q  LKD+  ++  I +     + ++  + +  +  ++ AQ L +                
Sbjct: 1351 QTQLKDLTQEEQNIRANARQQEQIQNQKIQELINENREAQNLVEILQKQIVQIQYE---- 1406

Query: 297  KQSIEPSCEEKTEIEEKGSLEIANM-TELTKKIELLEH----LNCQIRQTNKEL---ENK 348
            K+ IE    EK    +  S EI +  T+  +KIE+L+     L  Q +QT+ E+   +N+
Sbjct: 1407 KEKIEEELSEKNLQLDNYSNEIEDQKTQFLQKIEILQQNQQILEIQKKQTDNEILNYQNQ 1466

Query: 349  LATMGTESKAVSSPSKKGSPLISRK--SGRNTASKMKSPWSQLSSETLNQDTDKKINKNE 406
            +  +  ++  + +  K  S  I +   S +      K    QL ++ + +  +K I  +E
Sbjct: 1467 IEKLNQDNLQLQNELKVLSSNIQKDIDSMKEKQIAEKDAQLQLKNQEIKELKEKNIQLDE 1526

Query: 407  ----IAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEG 462
                I +L+  I+  N+   + +  + E +            K+    Q  L+  + +E 
Sbjct: 1527 KMKLIGELQNQIRQTNEKFQENQQKLQELEITINQLNQGIQTKEQE-CQESLKKSRELED 1585

Query: 463  PSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAA 522
              L+    N + ++ +  +QE++ Q      K+ N + + ++LK  +++++++ +E    
Sbjct: 1586 RLLVAQQENKKLISSVENLQEEISQ------KNQNEQTIQDELKQFQQEVSKIKEEKILQ 1639

Query: 523  NKNMIKVKSNHKL---KLKQMQKTIDNFSKVSDSNKEIVR-LTEELHHLSQKVAELEEEK 578
               +I   +   L   K+ Q+    D      +  K++++ L ++L    Q+  + E   
Sbjct: 1640 ESEIISKNTQLNLQEQKISQLNDEKDYLKTQMNEGKDMLKDLQQKLELQQQRQQKYEALV 1699

Query: 579  GNLQLHLVDYDSGRMIE--SDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQK 636
             N +L  +        E  S      +++EN A+ +L +I L+E  K    Q     Q  
Sbjct: 1700 KNEELKYLQKIENLETELSSQQVNSKLKIEN-AKRKLHSI-LIEFGKCKRQQ-----QHS 1752

Query: 637  YDEVEDKLADISQLQSDQVCSEIKSVH-LEEQIDALSASKKELALVIENLKLDKEQLYGT 695
             + ++D+L   ++     +   +K +  +  QI  L  + +EL  ++        Q+Y  
Sbjct: 1753 TNFIKDQLVKFNKTYQTILVKLVKKLSVINSQIAQLKLNHQELDDMLRVQVKINPQIYKH 1812

Query: 696  IKDLENDKEDIMNKLQNYIQ------ENMDLTDKLEKMSAEKISELLAKINHEEQS---K 746
            +  L+  +E ++   +  IQ      ENM   D+  K   + +S   + + ++ Q    K
Sbjct: 1813 LNQLQQQQESVVKSFKEKIQQLMSQQENMLFADENRKQEIQSLSTDRSDLKNQLQETNQK 1872

Query: 747  IQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRY---SLERKADQLG 803
            +Q Q  I+ +++E    I+ +ES+   Y+ +I     +I    ++     +L+ +  QL 
Sbjct: 1873 LQQQQQINLELKEE---IQRLESQNLLYQGQIQEKNSAIDQQNEKCKLIPNLKNEIQQLE 1929

Query: 804  SYLQEKQKAYSE----YTIQEDELVNRLAVLMDHDR-VVEKQLLEIEHENKELQKKNQIL 858
               Q +Q   +E    + +  D    ++  L + +R ++  Q ++ +    +LQK  Q L
Sbjct: 1930 QQRQRQQTMINEIQASFQVTIDHQQEQIQSLKEQNRDLLSGQEIKTQDIYLKLQKLEQQL 1989

Query: 859  LEENQ-NLQI--SLSDMQQHYNALVEKANRTDLAESES-TKYQTQLRDLESNLKRITHEH 914
            ++E Q + QI   LS   +    L + A R +L+E ++ T     L D   NLK  T   
Sbjct: 1990 IKEKQFSQQIFDKLSSKDEEIQQL-QLAQRKNLSEIDNLTNINEDLNDKIENLKDQTQRF 2048

Query: 915  QTLIVQKKKEIEDL-EIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNI-- 971
            Q    +K++ I +L E  +N  ++   + KK+   + +  +      + + Q  KN+I  
Sbjct: 2049 QVYFSEKEETIRNLKETVYNQNLQLEEKGKKLNQLQNDNEVLRKKYKDQEEQMMKNDIKF 2108

Query: 972  ENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQK 1031
            +  N  +E++ K+  +     + K+   +   TE++  E  KL  L +   ++I  L +K
Sbjct: 2109 QRQNNRMEQIQKLIKDY--PKISKEIGDTIKNTEEFCLE--KLRFLTQLFMKKIQTLQEK 2164

Query: 1032 INNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEE-LQILVREQDD 1090
            I  ++ +    +   + +L Q   + + M  +   ++ +  D   H ++ L+  + E+D 
Sbjct: 2165 IEESETANEQEIQKLKKQLQQQQQQYDEMFSQTLTINNENPDMMTHFKDVLKNAISERDQ 2224

Query: 1091 QIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEF 1150
              +ELK+ K  F+      E   +   ++ + D                  +  QE  +F
Sbjct: 2225 FQQELKQKKEQFDN--ASVENNYLKLQVQNLKDQLEQKWNESANQSLDLSSIDNQEIRKF 2282

Query: 1151 IQERSVLQEQSAKLNTELQECYTKI-IQLETLNTELTGHDVVNQEQINQLKSKLEQLNTE 1209
              E S +   +  ++  +Q  +TK  +Q++    +L       Q+Q     +K   L  E
Sbjct: 2283 --EHSSINNATI-IDPTVQSGHTKSSLQIKEFQNQLAQQ---LQQQNENNNTKFYDLQLE 2336

Query: 1210 NDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYE 1269
             D+    + + + ++   +D +  E  ++ K     +  ++Q ++   +    + + + +
Sbjct: 2337 IDSYKQEIEKYKMNL---IDYQQEE-QKMVKMISDLKRENYQLSQTINQTDTKSLKQQIK 2392

Query: 1270 QLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKE 1303
            QLL S   S Q +  +     Q+ S   +L D+E
Sbjct: 2393 QLLQSFLVSLQNQAQETEDYFQILSKMLELTDQE 2426


>UniRef50_A0DXX1 Cluster: Chromosome undetermined scaffold_69, whole
            genome shotgun sequence; n=2; Paramecium tetraurelia|Rep:
            Chromosome undetermined scaffold_69, whole genome shotgun
            sequence - Paramecium tetraurelia
          Length = 3066

 Score =  165 bits (402), Expect = 7e-39
 Identities = 275/1450 (18%), Positives = 624/1450 (43%), Gaps = 128/1450 (8%)

Query: 149  NTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXX 208
            N  K+  + L    +++  +   +  LQ+K+ EK+++I+ K++                 
Sbjct: 1416 NEKKQLQDQLHQKNLQIAALNDELSKLQQKVFEKEKVIDEKDR--EFRNSQLIKTYQDNC 1473

Query: 209  XXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEIS 268
               ++   +  +++E    +E     EKQ+ +K++E +    SS+       E+   + S
Sbjct: 1474 NKADELISKNNQIEETLNNLEVRLA-EKQQRVKELELQIGADSSISNIQDPRESGMIK-S 1531

Query: 269  LEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIAN-MTELTKK 327
             +  +  Q L+Q              L K  IE    E  E  +K +LE+ N + +L K+
Sbjct: 1532 YDQEQDTQ-LQQQEQVLQGYSMNIDQL-KNKIEQLNSELAE-RDKTNLELRNQVADLKKQ 1588

Query: 328  I---ELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKS 384
            I   +L +     I++ NK+L+++++ +  ++       +     +  K  R     M+ 
Sbjct: 1589 IHGYQLAQQDVKVIKKQNKQLQDEISALVQDNLNYEDLIRDSEFKLQEKKSRVKELDMEI 1648

Query: 385  PWSQLSSETLNQDTDKKINKNEIAKLEMVIQ---SLNKDLVDKEYVISEKDTXXXXXXXX 441
              +++  +   Q  + ++ + +I + + +I+    L++ L + E  I +K          
Sbjct: 1649 KNAEIQIQVEKQMKENQLLQQKIQQTDELIKKNLELDEALTNLELRILDKQQQLSQKEAR 1708

Query: 442  XXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDL 501
               +++ I Q  +   Q        ++ T T   +  A+ Q  L QE N+     N+ +L
Sbjct: 1709 LSNQNSRILQQPMYIYQEDSDDKASNIRTET---SPRAQNQHPLIQEHNN-----NLSEL 1760

Query: 502  IEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLT 561
               +   +EQ+ QL+ + D+     ++ K   +L++  +++      ++   N+ +  L 
Sbjct: 1761 TSSINQMQEQVRQLSLD-DSELDFYLQQKKEKQLEIDSLKQ------QLFQQNEVMQDLK 1813

Query: 562  EELHHLSQKVAELEEEKGNLQ--LHLVDYDSGRMIESDVYKK-MIEMENLAETRLKAISL 618
            +E     Q++ +L++E  N    +  +     +MIE ++ KK   + + +  +    I  
Sbjct: 1814 QEQIEKQQQIDQLKKENSNFDELVEELQQSQKQMIEQEIQKKESNQPQEIGGSEQSEIIK 1873

Query: 619  LESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKEL 678
             +S+  +L ++LH L+Q   ++++++A+      D +  ++++V  +++ D    +K+  
Sbjct: 1874 TKSENLELSKKLHDLKQSQKQLKNQIANY-----DYLILDLETVVADKKNDIQRLNKENQ 1928

Query: 679  ALVIENLK-------LDKEQ--LYGTIKDLENDKEDIMNKLQNYIQENM-DLTDKLEKMS 728
            +   +N K       L KEQ  L   +K LE   ++ + + +  +QE++  L +KL+++ 
Sbjct: 1929 SYQQQNRKQKGRRDLLHKEQNNLQYQLKLLEPQLQE-LQQTEKQLQESVTQLEEKLKQLD 1987

Query: 729  AEKISELLAKINHEEQ--SKIQTQFG-IDAKIQERDLYIENIESELSKYKSRICRLEESI 785
             EK  +L  +IN ++Q  S ++ Q   I+ +I ++    + ++SEL++ +     +E+ +
Sbjct: 1988 -EKQKQLENQINQKQQITSALELQLSTINQEILQQQDKKQQLDSELNQLRDENQGIEQEV 2046

Query: 786  AVMED---RRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLL 842
             +  +      +L  + D L   + E ++ Y     ++     ++ +L+  +    K++ 
Sbjct: 2047 KIYRNLSLEDITLNEQIDALTKQIHEDKQTYETLQDEQKATQEQINLLLPQN----KEID 2102

Query: 843  EIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRD 902
            E++ E  +LQ    +  E   NLQ+ L    +  N + ++ + T+    E+      L +
Sbjct: 2103 ELK-ETAKLQYAQNV--EALNNLQLELQQKIEQKNKVFQEVSDTEKYLEENNHVLQDLNE 2159

Query: 903  LESNLKRITHEHQTLI----VQKKKEIEDLEIE------FNTQIESAIRDKKVLNEKYEK 952
             ++NL+    + + L+     + K+  E LE E       N ++E  ++ K+V  ++  K
Sbjct: 2160 RKANLEDQIKKEEVLVNAVSAKSKRLDETLEAEKQNYNVLNAELEDLLKRKQVQEQELAK 2219

Query: 953  NIEYVTQLEA---QLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYIN 1009
              E + +++A   QL + +   +NL   +E+ NK ++E+  K +       P+  EQ + 
Sbjct: 2220 AKEEIQKMQADQEQLLQQQQQFKNLKEQIEQYNK-DIEINLKII-------PEREEQLV- 2270

Query: 1010 EINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSK 1069
               +L  ++++KDE + A   +++        +  D E K      +LE+    ++ + +
Sbjct: 2271 ---QLKCIIEKKDEVLSATQAEVDKLNKQIDEIQQDKEQK----EKELEDQSNLVKSIEE 2323

Query: 1070 QLLDSKQHNEELQ-----ILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDD 1124
            Q++D  Q  ++L+     I +++ + ++ E  E  +  +  +   E   +   ++ + DD
Sbjct: 2324 QIIDKYQREKDLKDQLDSIQLKDLEAELNEKMEQSMAQQEMLDSIEQ--LKQQVQQLRDD 2381

Query: 1125 ANNVDXXXXXXXXXXXXLK---VQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETL 1181
               +              K    Q+++E I+    L   SA++     +   K  QL+ L
Sbjct: 2382 ETQLKQQIQGQESLNNSKKQELEQKQQEKIELEQDLHSASAQMEEMKFQLEEKNEQLDKL 2441

Query: 1182 NTEL--TGHDVVNQEQINQLKSK-LEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAEL 1238
            N +      D    E + QLK K L+QL  + +NL+  +  + + +  A  Q    + + 
Sbjct: 2442 NDQFKKVDEDSKMMEAVLQLKEKELKQLQKKKENLIEELERINNDVVEAQKQL---VTQR 2498

Query: 1239 WKQHL--AQREADFQKTEHELRVQLSAFESKYEQLLDSVQS----STQEETNKIVTMEQV 1292
             KQ    A+ +   +  E +++ ++++  S+   L D +Q     S +    K    ++V
Sbjct: 2499 KKQRSLGAEPQQQDENMEEDIQDKITSLNSRNNNLKDDLQKLVEMSPEPTERKPEEQQEV 2558

Query: 1293 TSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEI----EDEKVAFXXXXXXXXXXXXXX 1348
                  +Q  +     +Q+   D   +IEIL   I    + ++                 
Sbjct: 2559 KDAPAPVQVSQFAPDRVQQTLQDRDKKIEILEMTISTLQQQQQERMSMIPSMFQSKLSVQ 2618

Query: 1349 XXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQ 1408
                  ++    ++Q++     +E    L+               ++ D   K   L  +
Sbjct: 2619 PSFFMDDDPLLLELQDK-FTKESELLKDLQNKIKQTAESHYALSLQLKDWAEKENRLAKE 2677

Query: 1409 LELKDSEIYQKTHEYTITLTQRND---EFENVRQQLVEYEKRIEDLTYEKESELAILRLK 1465
            L+ +   + Q   E      +++D   E  NV Q++   E   +D  YE+E   A  + K
Sbjct: 2678 LDTRRQSVEQIEFELQAVFAKQSDLESEKVNVLQRIYSLEVETQDF-YEQE---ANTKNK 2733

Query: 1466 MHENANHYETMQK---ESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEM 1522
            + E  ++ +T+ K   ES+ + ++L   + +   E   L +QV  L    E +     ++
Sbjct: 2734 LKEKKDYLQTLYKNLIESDQKLLQLRNRMALYSQEGRQLAEQVENLENEKENKQQHLQDI 2793

Query: 1523 QTALENQEIE 1532
            Q  LE+ E+E
Sbjct: 2794 QADLEHVEME 2803



 Score =  139 bits (337), Expect = 5e-31
 Identities = 292/1461 (19%), Positives = 619/1461 (42%), Gaps = 141/1461 (9%)

Query: 216  QQMTKMQENFIAMEAEWKDEKQRL--LKDIESKDVRISSLEEANKLL--EAARFEISLEH 271
            +QM  ++E     E E K  K+++  +++ +++       E  N  L  +  R E  L++
Sbjct: 1078 EQMEILKEQLKEKEDELKAYKEQIPSIQEYQNQQFLHQQEELVNTELRKDVQRLEDQLDN 1137

Query: 272  S-KLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIEL 330
              KL +EL+Q                K SI  S    ++I +        + E  +K + 
Sbjct: 1138 QLKLNKELQQRMDNQHESAALLSQKIKLSIHDSNSSSSQIIDNRQ----RLVEKQQKADE 1193

Query: 331  LEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGS-PLISRKSGRNTASKMKSPWSQL 389
            L   +  +    ++LE KL         + +  K+G+ P +  +S  N   K++ P +Q+
Sbjct: 1194 LVREHLSLDDLIEDLEKKLVEKNDYKDQLLNQLKEGTKPAV--QSEANEQPKVEQP-NQV 1250

Query: 390  SSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLI 449
             ++  NQ+   +  + EI+ ++ VI + N+D +       +              K+   
Sbjct: 1251 FAKQQNQEQFVEPIQ-EISDVQQVISN-NEDQISIPLQAGQILQQLEGDSQKQDIKEPNP 1308

Query: 450  AQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKV---------QEQLKQELNDEIKDVNVKD 500
            +Q +L +Q H      +    N +   ++ +V         Q+   +E  D  +   V D
Sbjct: 1309 SQ-ELSNQLHPTKSQPVFAQINQDAEPKLQQVKSSQGFTSPQDLFNKEGIDGQRLQEVWD 1367

Query: 501  LIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRL 560
            L++    A+ +I +L D +   NK   +++  +     + Q+ +    +VSDS  E  +L
Sbjct: 1368 LLKNNNDADRRIQELRDALQRKNKRKEQLEGVYN----KDQELVSQ--RVSDSVNEKKQL 1421

Query: 561  TEELHHLSQKVAELEEEKGNLQLHL------VDYDSGRMIESDVYKKMIEMENLAETRLK 614
             ++LH  + ++A L +E   LQ  +      +D        S + K   +  N A+  + 
Sbjct: 1422 QDQLHQKNLQIAALNDELSKLQQKVFEKEKVIDEKDREFRNSQLIKTYQDNCNKADELIS 1481

Query: 615  AISLLESQKFDLVQELHILQQKYDEVEDKL---ADISQLQSDQVCSEIKSVHLEE--QID 669
              + +E    +L   L   QQ+  E+E ++   + IS +Q  +    IKS   E+  Q+ 
Sbjct: 1482 KNNQIEETLNNLEVRLAEKQQRVKELELQIGADSSISNIQDPRESGMIKSYDQEQDTQLQ 1541

Query: 670  ALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMS- 728
                  +  ++ I+ LK   EQL   +   E DK ++  +L+N +    DL  ++     
Sbjct: 1542 QQEQVLQGYSMNIDQLKNKIEQLNSELA--ERDKTNL--ELRNQVA---DLKKQIHGYQL 1594

Query: 729  AEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVM 788
            A++  +++ K N + Q +I     +   +   DL I + E +L + KSR+  L+  I   
Sbjct: 1595 AQQDVKVIKKQNKQLQDEISAL--VQDNLNYEDL-IRDSEFKLQEKKSRVKELDMEIKNA 1651

Query: 789  EDR-RYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAV-LMDHDRVVEKQLLEIEH 846
            E + +   + K +QL     ++     +  ++ DE +  L + ++D  + + ++   + +
Sbjct: 1652 EIQIQVEKQMKENQLLQQKIQQTDELIKKNLELDEALTNLELRILDKQQQLSQKEARLSN 1711

Query: 847  ENKELQKKNQILLEENQ-----NLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLR 901
            +N  + ++   + +E+      N++   S   Q+ + L+++ N      SE T    Q++
Sbjct: 1712 QNSRILQQPMYIYQEDSDDKASNIRTETSPRAQNQHPLIQEHNNN---LSELTSSINQMQ 1768

Query: 902  DLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLE 961
            +    L     E    + QKK++    ++E ++  +   +  +V+ +  ++ IE   Q++
Sbjct: 1769 EQVRQLSLDDSELDFYLQQKKEK----QLEIDSLKQQLFQQNEVMQDLKQEQIEKQQQID 1824

Query: 962  AQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDY---TEQY-INEINKLNAL 1017
             QL++  +N + L   VEEL +   ++I++ +QK+++  P     +EQ  I +    N  
Sbjct: 1825 -QLKKENSNFDEL---VEELQQSQKQMIEQEIQKKESNQPQEIGGSEQSEIIKTKSENLE 1880

Query: 1018 LKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQ------- 1070
            L +K  ++    +++ N   +Y  ++ D E+ +A     ++ + +E Q   +Q       
Sbjct: 1881 LSKKLHDLKQSQKQLKNQIANYDYLILDLETVVADKKNDIQRLNKENQSYQQQNRKQKGR 1940

Query: 1071 --LLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNV 1128
              LL  +Q+N + Q+ + E   Q++EL++T+   + ++ + E  +     E      N +
Sbjct: 1941 RDLLHKEQNNLQYQLKLLEP--QLQELQQTEKQLQESVTQLEEKL-KQLDEKQKQLENQI 1997

Query: 1129 DXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGH 1188
            +            L    +E  +Q++   Q+  ++LN +L++    I Q   +   L+  
Sbjct: 1998 NQKQQITSALELQLSTINQE-ILQQQDKKQQLDSELN-QLRDENQGIEQEVKIYRNLSLE 2055

Query: 1189 DVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGF--EIAELWKQHLAQR 1246
            D+   EQI+ L  ++ +     + L       +  I+  + Q     E+ E  K   AQ 
Sbjct: 2056 DITLNEQIDALTKQIHEDKQTYETLQDEQKATQEQINLLLPQNKEIDELKETAKLQYAQN 2115

Query: 1247 EADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVT--MEQVTSLQNKLQDKEE 1304
                   + EL+ ++      ++++ D+      EE N ++    E+  +L+++++ KEE
Sbjct: 2116 VEALNNLQLELQQKIEQKNKVFQEVSDT--EKYLEENNHVLQDLNERKANLEDQIK-KEE 2172

Query: 1305 HLRNL---QEKYADVINQIE-----ILRSEIED---EKVAFXXXXXXXXXXXXXXXXD-- 1351
             L N    + K  D   + E     +L +E+ED    K                   D  
Sbjct: 2173 VLVNAVSAKSKRLDETLEAEKQNYNVLNAELEDLLKRKQVQEQELAKAKEEIQKMQADQE 2232

Query: 1352 -LRTENQSYKQMQEQ-----SILNIN--------EENAQLKKSSXXXXXXXXXXXXRVND 1397
             L  + Q +K ++EQ       + IN        E+  QLK                V+ 
Sbjct: 2233 QLLQQQQQFKNLKEQIEQYNKDIEINLKIIPEREEQLVQLKCIIEKKDEVLSATQAEVDK 2292

Query: 1398 AEAKVLELTHQLELKDSEIYQKTH------EYTITLTQRN----DEFENVRQQLVEYE-- 1445
               ++ E+    E K+ E+  +++      E  I   QR     D+ ++++ + +E E  
Sbjct: 2293 LNKQIDEIQQDKEQKEKELEDQSNLVKSIEEQIIDKYQREKDLKDQLDSIQLKDLEAELN 2352

Query: 1446 KRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQV 1505
            +++E    ++E   +I +LK        +  Q + +I+  + +   N K  E     ++ 
Sbjct: 2353 EKMEQSMAQQEMLDSIEQLKQQVQQLRDDETQLKQQIQGQESLN--NSKKQELEQKQQEK 2410

Query: 1506 AELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNL---QNMVRASSSKIQKHVSFAS 1562
             EL + L    A+  EM+  LE +  ++  LND+   +     M+ A     +K +    
Sbjct: 2411 IELEQDLHSASAQMEEMKFQLEEKNEQLDKLNDQFKKVDEDSKMMEAVLQLKEKELKQLQ 2470

Query: 1563 DTKQGRDEQLDNTMNKELLDA 1583
              K+   E+L+  +N ++++A
Sbjct: 2471 KKKENLIEELER-INNDVVEA 2490



 Score =  133 bits (321), Expect = 4e-29
 Identities = 252/1342 (18%), Positives = 565/1342 (42%), Gaps = 99/1342 (7%)

Query: 215  KQQMTKMQENFIAMEAEWKDEKQRLLKDIESK-DVRISSLEEANKLLEAARFEISLEHSK 273
            K+Q  ++Q+   A+  +  + +  L++D E K   + S ++E +  ++ A  +I +E   
Sbjct: 1603 KKQNKQLQDEISALVQDNLNYED-LIRDSEFKLQEKKSRVKELDMEIKNAEIQIQVEKQM 1661

Query: 274  LAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEH 333
               +L Q              L K+++E   E  T +E +    +    +L++K   L +
Sbjct: 1662 KENQLLQQKIQQTDE------LIKKNLELD-EALTNLELR---ILDKQQQLSQKEARLSN 1711

Query: 334  LNCQIRQT-----NKELENKLATMGTESKAVSSPSKKGSPLISRKSGR-----NTASKMK 383
             N +I Q       ++ ++K + + TE+   S  ++   PLI   +       ++ ++M+
Sbjct: 1712 QNSRILQQPMYIYQEDSDDKASNIRTET---SPRAQNQHPLIQEHNNNLSELTSSINQMQ 1768

Query: 384  SPWSQLSSETLNQD---TDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXX 440
                QLS +    D     KK  + EI  L+  +   N+ + D +    EK         
Sbjct: 1769 EQVRQLSLDDSELDFYLQQKKEKQLEIDSLKQQLFQQNEVMQDLKQEQIEKQQQIDQLKK 1828

Query: 441  XXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKD 500
                 D L+ +LQ   +Q +E           +++   ++  E +K +  +      + D
Sbjct: 1829 ENSNFDELVEELQQSQKQMIEQEIQKKESNQPQEIGG-SEQSEIIKTKSENLELSKKLHD 1887

Query: 501  LIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVR- 559
            L +  K  + QI    D +    + ++  K N   +L +  ++    ++     ++++  
Sbjct: 1888 LKQSQKQLKNQIANY-DYLILDLETVVADKKNDIQRLNKENQSYQQQNRKQKGRRDLLHK 1946

Query: 560  ----LTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKA 615
                L  +L  L  ++ EL++ +  LQ  +   +  ++ + D  +K  ++EN    + + 
Sbjct: 1947 EQNNLQYQLKLLEPQLQELQQTEKQLQESVTQLEE-KLKQLD--EKQKQLENQINQKQQI 2003

Query: 616  ISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASK 675
             S LE Q   + QE+   Q K  +++ +L  +   ++  +  E+K ++    ++ ++ ++
Sbjct: 2004 TSALELQLSTINQEILQQQDKKQQLDSELNQLRD-ENQGIEQEVK-IYRNLSLEDITLNE 2061

Query: 676  KELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISEL 735
            +  AL  + +  DK Q Y T++D +   ++ +N L    +E  +L +  +   A+ + E 
Sbjct: 2062 QIDALT-KQIHEDK-QTYETLQDEQKATQEQINLLLPQNKEIDELKETAKLQYAQNV-EA 2118

Query: 736  LAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSL 795
            L  +  E Q KI+ +  +  ++ + + Y+E     L     R   LE+ I   E    ++
Sbjct: 2119 LNNLQLELQQKIEQKNKVFQEVSDTEKYLEENNHVLQDLNERKANLEDQIKKEEVLVNAV 2178

Query: 796  ERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKN 855
              K+ +L   L+ +++ Y+    + ++L+ R        +V E++L + + E +++Q   
Sbjct: 2179 SAKSKRLDETLEAEKQNYNVLNAELEDLLKR-------KQVQEQELAKAKEEIQKMQADQ 2231

Query: 856  QILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQ 915
            + LL++ Q  + +L +  + YN  +E  N   + E E  +   QL+ +      +    Q
Sbjct: 2232 EQLLQQQQQFK-NLKEQIEQYNKDIE-INLKIIPERE--EQLVQLKCIIEKKDEVLSATQ 2287

Query: 916  TLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLN 975
              + +  K+I++++ +   Q E  + D+  L +  E+ I    Q E  L++  ++I+  +
Sbjct: 2288 AEVDKLNKQIDEIQ-QDKEQKEKELEDQSNLVKSIEEQIIDKYQREKDLKDQLDSIQLKD 2346

Query: 976  MNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALN----QK 1031
            +  E   KM   +     Q++   S +  +Q + ++      LKQ+ +   +LN    Q+
Sbjct: 2347 LEAELNEKMEQSM----AQQEMLDSIEQLKQQVQQLRDDETQLKQQIQGQESLNNSKKQE 2402

Query: 1032 INNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQ 1091
            +   Q   + +  D  S  AQ       +EE+ +++ K     K+ +E+ +++     + 
Sbjct: 2403 LEQKQQEKIELEQDLHSASAQMEEMKFQLEEKNEQLDKLNDQFKKVDEDSKMM-----EA 2457

Query: 1092 IKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFI 1151
            + +LKE +L  +    K E +I    +E +++D                 L  + +++  
Sbjct: 2458 VLQLKEKEL--KQLQKKKENLI--EELERINNDVVEAQKQLVTQRKKQRSLGAEPQQQDE 2513

Query: 1152 QERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTEND 1211
                 +Q++   LN+        + +L  ++ E T      Q+++    + ++      D
Sbjct: 2514 NMEEDIQDKITSLNSRNNNLKDDLQKLVEMSPEPTERKPEEQQEVKDAPAPVQVSQFAPD 2573

Query: 1212 NLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQL 1271
             +  T+ + R      ++     + +  ++ ++   + FQ    +L VQ S F      L
Sbjct: 2574 RVQQTLQD-RDKKIEILEMTISTLQQQQQERMSMIPSMFQS---KLSVQPSFFMDDDPLL 2629

Query: 1272 LDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEK 1331
            L+     T+E        E +  LQNK++   E    L  +  D   +   L  E++  +
Sbjct: 2630 LELQDKFTKES-------ELLKDLQNKIKQTAESHYALSLQLKDWAEKENRLAKELDTRR 2682

Query: 1332 VAFXXXXXXXXXXXXXXXXDLRTENQSYKQ---MQEQSILNINEENAQLKKSSXXXXXXX 1388
             +                 DL +E  +  Q     E    +  E+ A  K          
Sbjct: 2683 QS-VEQIEFELQAVFAKQSDLESEKVNVLQRIYSLEVETQDFYEQEANTKNKLKEKKDYL 2741

Query: 1389 XXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRI 1448
                  + +++ K+L+L +++ L   E  Q   +    +    +E EN +Q L + +  +
Sbjct: 2742 QTLYKNLIESDQKLLQLRNRMALYSQEGRQLAEQ----VENLENEKENKQQHLQDIQADL 2797

Query: 1449 EDLTYEKESELAILRLKMHENANHYETMQKESEIE-RVKLIEELNVKITESVSLNKQVAE 1507
            E +  EK+ + A+++    E +   ET Q++ ++E +   +   N ++   +   +  A 
Sbjct: 2798 EHVEMEKQEKQALVQSIAKEIS---ETQQEKDKLEIQYATVHSKNQQLKSQIGYEE--AF 2852

Query: 1508 LNKALEE-EVAKTNEMQTALEN 1528
              K L+E E+AK  + QT  +N
Sbjct: 2853 YQKLLQELEIAKKRD-QTKFQN 2873



 Score =  110 bits (264), Expect = 4e-22
 Identities = 211/1180 (17%), Positives = 497/1180 (42%), Gaps = 84/1180 (7%)

Query: 446  DTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQE--QLKQELNDEIK---DVNVKD 500
            ++ +A  ++E+++  +   L     +  D  + AK+ E   L ++L++E+     +  +D
Sbjct: 806  ESKLANRKIENEELKK--QLQEANKDYNDQQKRAKMYELYMLNKDLDEEVSLSPKLQEED 863

Query: 501  LI-EKLKSAEEQITQLNDEIDAANK-NMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIV 558
            L  E+L+   +Q  +L    D   +   + +K  ++ K+K ++K   N        +   
Sbjct: 864  LQNEQLEQLNQQAPELEQPEDPQKQAKKLTIKDKYEKKIKDLKKENRNLIAQLKQLRGAQ 923

Query: 559  RLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEME-NLAETRLKAIS 617
            +  +      +  A+L++   ++Q    D +    ++     K I+++ N  + + +   
Sbjct: 924  QQDQSNRPQQEDDAKLKQSNPSVQN---DNEHPEQVQQQQQPKPIDIQKNTQDLQQQYEK 980

Query: 618  LLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKE 677
             LE Q  DL+QE+  LQ   + +E K+    + + +Q+ +++ ++  + +        +E
Sbjct: 981  GLEKQ-VDLIQEVQSLQDIIENLEQKVQQKKEAK-EQLEAQLCALDKKNESSQQDPQLQE 1038

Query: 678  LALVIENLKLDKEQLYGT------IKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSA-- 729
             A +    KLD+E L         I  L++   D  NKL+        L +K +++ A  
Sbjct: 1039 SATMASTSKLDQEALQRQYDQEVQISRLKDQLADKQNKLEQMEILKEQLKEKEDELKAYK 1098

Query: 730  EKISELLAKIN----HEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESI 785
            E+I  +    N    H+++  + T+   D  +Q  +  ++N      + + R+    ES 
Sbjct: 1099 EQIPSIQEYQNQQFLHQQEELVNTELRKD--VQRLEDQLDNQLKLNKELQQRMDNQHESA 1156

Query: 786  AVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIE 845
            A++  +       ++   S + + ++   E   + DELV     L D    +EK+L+E +
Sbjct: 1157 ALLSQKIKLSIHDSNSSSSQIIDNRQRLVEKQQKADELVREHLSLDDLIEDLEKKLVE-K 1215

Query: 846  HENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLES 905
            ++ K+ Q  NQ+       +Q   ++  +     VE+ N+    +    ++   ++++  
Sbjct: 1216 NDYKD-QLLNQLKEGTKPAVQSEANEQPK-----VEQPNQVFAKQQNQEQFVEPIQEISD 1269

Query: 906  NLKRITHEHQTLIV--QKKKEIEDLEIEFNTQ-IESAIRDKKVLNEKYEKNIEYV-TQLE 961
              + I++    + +  Q  + ++ LE +   Q I+     +++ N+ +    + V  Q+ 
Sbjct: 1270 VQQVISNNEDQISIPLQAGQILQQLEGDSQKQDIKEPNPSQELSNQLHPTKSQPVFAQIN 1329

Query: 962  AQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQK 1021
               +     +++        +  N E ID    ++              I +L   L++K
Sbjct: 1330 QDAEPKLQQVKSSQGFTSPQDLFNKEGIDGQRLQEVWDLLKNNNDADRRIQELRDALQRK 1389

Query: 1022 DEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEEL 1081
            ++    L    N  Q      VSD  ++  Q   +L     ++  ++ +L   +Q   E 
Sbjct: 1390 NKRKEQLEGVYNKDQELVSQRVSDSVNEKKQLQDQLHQKNLQIAALNDELSKLQQKVFEK 1449

Query: 1082 QILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXX 1141
            + ++ E+D + +  +  K T++ N  K + +I  S    + +  NN++            
Sbjct: 1450 EKVIDEKDREFRNSQLIK-TYQDNCNKADELI--SKNNQIEETLNNLEVRLAEKQQRVKE 1506

Query: 1142 LKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKS 1201
            L++Q   +          +S  + +  QE  T++ Q E +   L G+ +     I+QLK+
Sbjct: 1507 LELQIGADSSISNIQDPRESGMIKSYDQEQDTQLQQQEQV---LQGYSM----NIDQLKN 1559

Query: 1202 KLEQLNTENDNLLSTVAELRSSISSAVDQ-RGFEIAELWKQHLAQREADFQKTEHELRVQ 1260
            K+EQLN+E      T  ELR+ ++    Q  G+++A+       Q     +K   +L+ +
Sbjct: 1560 KIEQLNSELAERDKTNLELRNQVADLKKQIHGYQLAQ-------QDVKVIKKQNKQLQDE 1612

Query: 1261 LSAF---ESKYEQLLDSVQSSTQEETNKIVTME-QVTSLQNKLQDKEEHLRNLQEKYADV 1316
            +SA       YE L+   +   QE+ +++  ++ ++ + + ++Q  E+ ++  Q     +
Sbjct: 1613 ISALVQDNLNYEDLIRDSEFKLQEKKSRVKELDMEIKNAEIQIQ-VEKQMKENQLLQQKI 1671

Query: 1317 INQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQ 1376
                E+++  +E ++                   + R  NQ+ + +Q+   +   + + +
Sbjct: 1672 QQTDELIKKNLELDEALTNLELRILDKQQQLSQKEARLSNQNSRILQQPMYIYQEDSDDK 1731

Query: 1377 LKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKT---HEYTITLTQRND- 1432
                              + +    + ELT  +     ++ Q +    E    L Q+ + 
Sbjct: 1732 ASNIRTETSPRAQNQHPLIQEHNNNLSELTSSINQMQEQVRQLSLDDSELDFYLQQKKEK 1791

Query: 1433 --EFENVRQQLVEYEKRIEDLTYEK-ESELAILRLKMHENANHYETMQKESEIERVKLIE 1489
              E ++++QQL +  + ++DL  E+ E +  I +LK  EN+N  E +++  + ++  + +
Sbjct: 1792 QLEIDSLKQQLFQQNEVMQDLKQEQIEKQQQIDQLK-KENSNFDELVEELQQSQKQMIEQ 1850

Query: 1490 ELNVK------------ITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLN 1537
            E+  K             +E +    +  EL+K L +      +++  + N +  I+ L 
Sbjct: 1851 EIQKKESNQPQEIGGSEQSEIIKTKSENLELSKKLHDLKQSQKQLKNQIANYDYLILDLE 1910

Query: 1538 DEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMN 1577
              + + +N ++  + + Q +    +  ++GR + L    N
Sbjct: 1911 TVVADKKNDIQRLNKENQSYQQ-QNRKQKGRRDLLHKEQN 1949



 Score =   99 bits (238), Expect = 5e-19
 Identities = 200/996 (20%), Positives = 423/996 (42%), Gaps = 83/996 (8%)

Query: 626  LVQELHILQQKYDEVEDKLADISQL-----QSDQVCS-EIKSVHLEEQIDALSASKKELA 679
            L+ + HI+ Q+  E+E+    + QL     Q++QV   +  +V L+ QI+ L +  +E  
Sbjct: 31   LMNQEHIIWQQAREIEELRRRLKQLESLDFQNEQVLHLQNINVQLKTQIEFLRSQIQEKD 90

Query: 680  LVIENL-----KLDKEQLYGTIKDL--EN-DKEDIMNKLQNYIQENMDLTDKLEKMSAEK 731
             +I  L     +    ++    + L  +N   ++I+  LQN I  N D      K     
Sbjct: 91   AMIAQLTSKPVQAASPEILAAQQQLIQQNLQLQNIIGDLQNQIL-NKDAVIGQLKTQEST 149

Query: 732  ISELLAKINHEEQSKIQ----TQFGID--AKIQERDLYIEN----IESELSKYKSRICRL 781
            + +L+ ++    QSK      TQ G +  + + E   Y E     IE  + +Y+     +
Sbjct: 150  LDQLIGQLQSNIQSKRNKVGVTQQGNETLSVLNELQQYPEALQDVIERIIQEYRRMQFLI 209

Query: 782  EESIAVMEDRRYSLERKADQLGSYLQE-KQKAYSEY-TIQEDELVNRLAVLMDHDRVVEK 839
            EE    +++ +  L+ +  +    + E K++  S   + Q  +L  + A + D    +E+
Sbjct: 210  EEKDIEIQNLKSRLQLQQQKANDSISEIKKRDISPIRSDQALDLAKQTASMDDMINDLER 269

Query: 840  QLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTK---- 895
            +L+  ++  KELQ K   +  +N  L+   S  +      V++  + +L  ++  K    
Sbjct: 270  KLMSQDNRKKELQAKLLEVGTQNVELEKQWSQSKDQLPKSVDELVKQNLDVNDKIKELQK 329

Query: 896  ----YQTQLRDLESNLKRITHEHQTLIVQKK-KEIEDLEIEFNT-QIESAIRDKKVLNEK 949
                 Q +L  ++  +  I    Q L  Q+   + ED   + NT Q  + + D  + N++
Sbjct: 330  SLLSKQNELDQVQKQINTINDNQQQLQPQQNLNKQEDQVDKVNTSQNRNNVDDLVLENQQ 389

Query: 950  YEKNI----EYVTQLEAQLQEYKNNIENLNMNVEELNKMNLE----LIDKHVQKQQTQSP 1001
             E  I    + +   +AQ ++ +N I+ LN++  + N  +L+    L+D   + Q+TQ  
Sbjct: 390  LEDLIVELQQKLVDKQAQKEDIENEIKKLNISALQQNLKDLQKQHGLLDNDNKNQKTQIQ 449

Query: 1002 DYTEQYINEINKLNALLKQKDEEIIALNQKINN---AQVSYMSMVSDYESK-LAQFTT-- 1055
               E+ IN+  ++   L Q+++E+   N +  +    Q   ++ + D ++K LA+ T   
Sbjct: 450  QLQEE-INQNKEIQQKLSQENKELQDQNNQTQSQIKQQEEKLAQLQDQKNKNLAKLTNDD 508

Query: 1056 --KLE---NMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTE 1110
              KL+   N  EE  ++ +QL+  +Q NEEL+   ++QD+Q  E + + +  ++   + E
Sbjct: 509  LLKLQEKFNQTEENNKILEQLV--QQLNEELR--KQQQDNQPLEEELSNIKNKLQKTEQE 564

Query: 1111 GMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQE 1170
               +   ++ + D  NN               K    +   Q+R+   E+  +    + +
Sbjct: 565  NSDLEQQVQQLEDQLNNFKKQQLQTKESA---KPSYSKSAEQQRTTPVEKFREPFQNIVD 621

Query: 1171 CYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQ 1230
                   L +LN +      V     N  +S+  +  T+    ++   ++  +    + +
Sbjct: 622  KEEFSFDLGSLNQQDFSSQEVTSSPENIKQSQFAKNKTQEGKFITIPLDIIKNYEYLIRE 681

Query: 1231 RGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSV---QSSTQEETNKIV 1287
            +  EI EL K  LA +         +     S  +      L++    Q++ Q   ++ V
Sbjct: 682  KENEIDEL-KNELANQGLQSIPLNFQTGNMGSDQQENANFQLEATAPNQNNEQNPEDQGV 740

Query: 1288 TMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKV----AFXXXXXXXXX 1343
            T+EQ   LQ  ++ K+++++ L ++  + + Q   L  E + +K+               
Sbjct: 741  TLEQ---LQKTIKTKDDYIQMLLDQIEE-MKQFGSLPEEQQKQKLEGNQKRSDDLVRQNI 796

Query: 1344 XXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVL 1403
                   DL ++  + K   E+    + E N                   +  D E  + 
Sbjct: 797  EIADIIIDLESKLANRKIENEELKKQLQEANKDYNDQQKRAKMYELYMLNKDLDEEVSLS 856

Query: 1404 ELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLV--EYEKRIEDLTYEKESELAI 1461
                + +L++ ++ ++ ++    L Q  D  +  ++  +  +YEK+I+DL  +KE+   I
Sbjct: 857  PKLQEEDLQNEQL-EQLNQQAPELEQPEDPQKQAKKLTIKDKYEKKIKDL--KKENRNLI 913

Query: 1462 LRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAK-TN 1520
             +LK    A   +   +  + +  KL ++ N  +       +QV +  +    ++ K T 
Sbjct: 914  AQLKQLRGAQQQDQSNRPQQEDDAKL-KQSNPSVQNDNEHPEQVQQQQQPKPIDIQKNTQ 972

Query: 1521 EMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQK 1556
            ++Q   E    + V L  E+ +LQ+++     K+Q+
Sbjct: 973  DLQQQYEKGLEKQVDLIQEVQSLQDIIENLEQKVQQ 1008



 Score =   99 bits (238), Expect = 5e-19
 Identities = 250/1293 (19%), Positives = 530/1293 (40%), Gaps = 134/1293 (10%)

Query: 396  QDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLE 455
            Q+ +K  N  +       +  LNKDL D+E  +S K              +    +L+  
Sbjct: 824  QEANKDYNDQQKRAKMYELYMLNKDL-DEEVSLSPKLQEEDLQNEQLEQLNQQAPELEQP 882

Query: 456  HQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEE-QITQ 514
                 +   L       + + ++ K    L  +L  +++    +D   + +  ++ ++ Q
Sbjct: 883  EDPQKQAKKLTIKDKYEKKIKDLKKENRNLIAQLK-QLRGAQQQDQSNRPQQEDDAKLKQ 941

Query: 515  LNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFS--------KVSDSNKEIVRLTEELHH 566
             N  +   N++  +V+   + K   +QK   +          K  D  +E+  L + + +
Sbjct: 942  SNPSVQNDNEHPEQVQQQQQPKPIDIQKNTQDLQQQYEKGLEKQVDLIQEVQSLQDIIEN 1001

Query: 567  LSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDL 626
            L QKV + +E K  L+  L   D  +   S    ++ E   +A T       L+ Q +D 
Sbjct: 1002 LEQKVQQKKEAKEQLEAQLCALDK-KNESSQQDPQLQESATMASTSKLDQEALQRQ-YD- 1058

Query: 627  VQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIE--N 684
             QE+ I + K D++ DK   + Q+       EI    L+E+ D L A K+++  + E  N
Sbjct: 1059 -QEVQISRLK-DQLADKQNKLEQM-------EILKEQLKEKEDELKAYKEQIPSIQEYQN 1109

Query: 685  LKL--DKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKM--SAEKISELLAKIN 740
             +    +E+L  T  +L  D + + ++L N ++ N +L  +++    SA  +S+ +    
Sbjct: 1110 QQFLHQQEELVNT--ELRKDVQRLEDQLDNQLKLNKELQQRMDNQHESAALLSQKIKLSI 1167

Query: 741  HEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKAD 800
            H+  S          ++ E+    + +  E       I  LE+ +    D +  L  +  
Sbjct: 1168 HDSNSSSSQIIDNRQRLVEKQQKADELVREHLSLDDLIEDLEKKLVEKNDYKDQLLNQLK 1227

Query: 801  QLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVE--KQLLEIEHENKELQKKNQIL 858
            + G+    + +A  +  +++   V   A   + ++ VE  +++ +++      + +  I 
Sbjct: 1228 E-GTKPAVQSEANEQPKVEQPNQV--FAKQQNQEQFVEPIQEISDVQQVISNNEDQISIP 1284

Query: 859  LEENQNLQISLSDMQQHY----NALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEH 914
            L+  Q LQ    D Q+      N   E +N+    +S+    Q   +D E  L+++    
Sbjct: 1285 LQAGQILQQLEGDSQKQDIKEPNPSQELSNQLHPTKSQPVFAQIN-QDAEPKLQQVKSSQ 1343

Query: 915  QTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENL 974
                 Q     E ++ +   ++   +++    N   ++ I+ +     +  + K  +E +
Sbjct: 1344 GFTSPQDLFNKEGIDGQRLQEVWDLLKN----NNDADRRIQELRDALQRKNKRKEQLEGV 1399

Query: 975  -NMNVEELNKMNLELID--KHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQK 1031
             N + E +++   + ++  K +Q Q  Q         +E++KL   + +K++ I   +++
Sbjct: 1400 YNKDQELVSQRVSDSVNEKKQLQDQLHQKNLQIAALNDELSKLQQKVFEKEKVIDEKDRE 1459

Query: 1032 INNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILV------ 1085
              N+Q+  +    D  +K  +  +K   +EE +  +  +L + +Q  +EL++ +      
Sbjct: 1460 FRNSQL--IKTYQDNCNKADELISKNNQIEETLNNLEVRLAEKQQRVKELELQIGADSSI 1517

Query: 1086 ----------------REQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVD 1129
                            +EQD Q+++ ++    + MNI +     + + IE ++ +    D
Sbjct: 1518 SNIQDPRESGMIKSYDQEQDTQLQQQEQVLQGYSMNIDQ-----LKNKIEQLNSELAERD 1572

Query: 1130 XXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHD 1189
                        LK Q     + ++ V  +   K N +LQ+  + ++Q + LN E    D
Sbjct: 1573 KTNLELRNQVADLKKQIHGYQLAQQDV--KVIKKQNKQLQDEISALVQ-DNLNYEDLIRD 1629

Query: 1190 VVNQEQINQLKSKLEQLNTENDNL-LSTVAELRSSISSAVDQRGFEIAELWKQHLAQREA 1248
              ++ ++ + KS++++L+ E  N  +    E +   +  + Q+  +  EL K++L   E 
Sbjct: 1630 --SEFKLQEKKSRVKELDMEIKNAEIQIQVEKQMKENQLLQQKIQQTDELIKKNL---EL 1684

Query: 1249 DFQKTEHELRV-----QLSAFESKYE----QLLDSVQSSTQEETN-KIVTMEQVTS--LQ 1296
            D   T  ELR+     QLS  E++      ++L       QE+++ K   +   TS   Q
Sbjct: 1685 DEALTNLELRILDKQQQLSQKEARLSNQNSRILQQPMYIYQEDSDDKASNIRTETSPRAQ 1744

Query: 1297 NKLQDKEEHLRNLQEKYADVINQIEILRS-EIEDEKVAFXXXXXXXXXXXXXXXXDLRTE 1355
            N+    +EH  NL E  + +    E +R   ++D ++ F                    +
Sbjct: 1745 NQHPLIQEHNNNLSELTSSINQMQEQVRQLSLDDSELDFYLQQKKEKQLEIDSLKQQLFQ 1804

Query: 1356 NQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXX---XXXRVNDAEAKVLELTHQLELK 1412
                 Q  +Q  +   ++  QLKK +               ++ + E +  E     E+ 
Sbjct: 1805 QNEVMQDLKQEQIEKQQQIDQLKKENSNFDELVEELQQSQKQMIEQEIQKKESNQPQEIG 1864

Query: 1413 DSEIYQ--KTHEYTITLTQRNDEFEN----VRQQLVEYEKRIEDL-TYEKESELAILRLK 1465
             SE  +  KT    + L+++  + +     ++ Q+  Y+  I DL T   + +  I RL 
Sbjct: 1865 GSEQSEIIKTKSENLELSKKLHDLKQSQKQLKNQIANYDYLILDLETVVADKKNDIQRLN 1924

Query: 1466 MHENANHYETMQKESEIERVKLIEELNVK---------ITESVSLNKQVAELNKALEEEV 1516
              EN ++ +  +K+     +   E+ N++         + E     KQ+ E    LEE++
Sbjct: 1925 K-ENQSYQQQNRKQKGRRDLLHKEQNNLQYQLKLLEPQLQELQQTEKQLQESVTQLEEKL 1983

Query: 1517 AKTNEMQTALENQ-----------EIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTK 1565
             + +E Q  LENQ           E+++ T+N EI   Q+  +   S++ +      D  
Sbjct: 1984 KQLDEKQKQLENQINQKQQITSALELQLSTINQEILQQQDKKQQLDSELNQ----LRDEN 2039

Query: 1566 QGRDEQLDNTMNKELLDAVPRAELDLAMYMLHQ 1598
            QG ++++    N  L D     ++D     +H+
Sbjct: 2040 QGIEQEVKIYRNLSLEDITLNEQIDALTKQIHE 2072



 Score = 98.7 bits (235), Expect = 1e-18
 Identities = 193/1013 (19%), Positives = 415/1013 (40%), Gaps = 86/1013 (8%)

Query: 147  LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXX 206
            L  T K+   +++ L+ K+K ++     L+ +IN+K QI      A              
Sbjct: 1965 LQQTEKQLQESVTQLEEKLKQLDEKQKQLENQINQKQQI----TSALELQLSTINQEILQ 2020

Query: 207  XXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDI---ESKDVRISSLEEANKLLEAA 263
                 +    ++ ++++    +E E K  +   L+DI   E  D     + E  +  E  
Sbjct: 2021 QQDKKQQLDSELNQLRDENQGIEQEVKIYRNLSLEDITLNEQIDALTKQIHEDKQTYETL 2080

Query: 264  RFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTE 323
            + E      ++   L Q               A Q++E     + E+++K   +     E
Sbjct: 2081 QDEQKATQEQINLLLPQNKEIDELKETAKLQYA-QNVEALNNLQLELQQKIEQKNKVFQE 2139

Query: 324  LTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMK 383
            ++   + LE  N  ++  N+   N    +  E   V++ S K   L        T    K
Sbjct: 2140 VSDTEKYLEENNHVLQDLNERKANLEDQIKKEEVLVNAVSAKSKRL------DETLEAEK 2193

Query: 384  SPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKD---LVDKEY-------VISEKDT 433
              ++ L++E  +    K++ + E+AK +  IQ +  D   L+ ++         I + + 
Sbjct: 2194 QNYNVLNAELEDLLKRKQVQEQELAKAKEEIQKMQADQEQLLQQQQQFKNLKEQIEQYNK 2253

Query: 434  XXXXXXXXXXGKDTLIAQLQ--LEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELND 491
                       ++  + QL+  +E +  +   +   V    + ++EI + +EQ ++EL D
Sbjct: 2254 DIEINLKIIPEREEQLVQLKCIIEKKDEVLSATQAEVDKLNKQIDEIQQDKEQKEKELED 2313

Query: 492  EIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVS 551
            +     VK + E++    ++   L D++D+     ++ + N K++    Q+  +    + 
Sbjct: 2314 QSN--LVKSIEEQIIDKYQREKDLKDQLDSIQLKDLEAELNEKMEQSMAQQ--EMLDSIE 2369

Query: 552  DSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRM-IESDVYKKMIEMENL-- 608
               +++ +L ++   L Q++   E    + +  L      ++ +E D++    +ME +  
Sbjct: 2370 QLKQQVQQLRDDETQLKQQIQGQESLNNSKKQELEQKQQEKIELEQDLHSASAQMEEMKF 2429

Query: 609  -AETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVH---L 664
              E + + +  L  Q F  V E   + +   ++++K     Q + + +  E++ ++   +
Sbjct: 2430 QLEEKNEQLDKLNDQ-FKKVDEDSKMMEAVLQLKEKELKQLQKKKENLIEELERINNDVV 2488

Query: 665  EEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKL 724
            E Q   ++  KK+ +L  E  + D           EN +EDI +K+ +    N +L D L
Sbjct: 2489 EAQKQLVTQRKKQRSLGAEPQQQD-----------ENMEEDIQDKITSLNSRNNNLKDDL 2537

Query: 725  EKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEES 784
            +K+   ++S    +   EEQ +++      A +Q      + ++  L     +I  LE +
Sbjct: 2538 QKL--VEMSPEPTERKPEEQQEVK---DAPAPVQVSQFAPDRVQQTLQDRDKKIEILEMT 2592

Query: 785  IAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRL--------AVLMDHDRV 836
            I+ ++ ++   + +   + S  Q K      + + +D L+  L         +L D    
Sbjct: 2593 ISTLQQQQ---QERMSMIPSMFQSKLSVQPSFFMDDDPLLLELQDKFTKESELLKDLQNK 2649

Query: 837  VEKQLLEIEH----ENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESE 892
            + KQ  E  +    + K+  +K   L +E    + S+  ++    A+   A ++DL ESE
Sbjct: 2650 I-KQTAESHYALSLQLKDWAEKENRLAKELDTRRQSVEQIEFELQAVF--AKQSDL-ESE 2705

Query: 893  STKYQTQLRDLESNLKRITHEHQTLIVQKKKEIED-LEIEFNTQIESAIRDKKVLNEKYE 951
                  ++  LE   +   +E +     K KE +D L+  +   IES   D+K+L  +  
Sbjct: 2706 KVNVLQRIYSLEVETQDF-YEQEANTKNKLKEKKDYLQTLYKNLIES---DQKLL--QLR 2759

Query: 952  KNIEYVTQLEAQLQEYKNNIENLNMNVEE-LNKMNLELIDKHVQKQQTQS-PDYTEQYIN 1009
              +   +Q   QL E   N+EN   N ++ L  +  +L    ++KQ+ Q+      + I+
Sbjct: 2760 NRMALYSQEGRQLAEQVENLENEKENKQQHLQDIQADLEHVEMEKQEKQALVQSIAKEIS 2819

Query: 1010 EINKLNALLKQKDEEIIALNQKINN----AQVSYMSMVSDYESKLAQFTTKLENMEEEMQ 1065
            E  +    L+ +   + + NQ++ +     +  Y  ++ + E    +  TK +N+  +  
Sbjct: 2820 ETQQEKDKLEIQYATVHSKNQQLKSQIGYEEAFYQKLLQELEIAKKRDQTKFQNLFSDGS 2879

Query: 1066 RVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTI 1118
              ++  L+  +       L R   + + +LKE      + I   E   I  TI
Sbjct: 2880 TQTEYDLEQFESLSTCTQLYRITKEDVYQLKENCKQRLIQIYTNENANIQQTI 2932



 Score = 98.7 bits (235), Expect = 1e-18
 Identities = 199/997 (19%), Positives = 424/997 (42%), Gaps = 92/997 (9%)

Query: 150  TIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXX 209
            T+ E+ +AL+    + K    T+ D Q+   E+  ++  +NK                  
Sbjct: 2058 TLNEQIDALTKQIHEDKQTYETLQDEQKATQEQINLLLPQNKEIDELKETAKLQYAQNVE 2117

Query: 210  XXEDTKQQMTKM--QENFIAMEA----EWKDEKQRLLKDIESKDVRISSLEEANKLLEAA 263
               + + ++ +   Q+N +  E     ++ +E   +L+D+     R ++LE+  K  E  
Sbjct: 2118 ALNNLQLELQQKIEQKNKVFQEVSDTEKYLEENNHVLQDLNE---RKANLEDQIKKEEVL 2174

Query: 264  RFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTE 323
               +S +  +L + LE               L K+  +   +E  + +E+     A+  +
Sbjct: 2175 VNAVSAKSKRLDETLEAEKQNYNVLNAELEDLLKRK-QVQEQELAKAKEEIQKMQADQEQ 2233

Query: 324  LTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMK 383
            L ++ +  ++L  QI Q NK++E  L  +    + +         +I +K    +A++ +
Sbjct: 2234 LLQQQQQFKNLKEQIEQYNKDIEINLKIIPEREEQLVQLKC----IIEKKDEVLSATQAE 2289

Query: 384  SPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXX 443
                    + + QD ++K  + E+     +++S+ + ++DK     EKD           
Sbjct: 2290 VDKLNKQIDEIQQDKEQK--EKELEDQSNLVKSIEEQIIDKYQ--REKDLKDQLDSIQL- 2344

Query: 444  GKDTLIAQLQLEHQQHMEGPSLIH-VGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLI 502
             KD L A+L  + +Q M    ++  +    + V ++   + QLKQ++  +    N K   
Sbjct: 2345 -KD-LEAELNEKMEQSMAQQEMLDSIEQLKQQVQQLRDDETQLKQQIQGQESLNNSKK-- 2400

Query: 503  EKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNK---EIVR 559
            ++L+  +++  +L  ++ +A+  M ++K   + K +Q+ K  D F KV + +K    +++
Sbjct: 2401 QELEQKQQEKIELEQDLHSASAQMEEMKFQLEEKNEQLDKLNDQFKKVDEDSKMMEAVLQ 2460

Query: 560  LTE-ELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKM-----IEMENLAETRL 613
            L E EL  L +K   L EE   +   +V+     + +    + +      + EN+ E   
Sbjct: 2461 LKEKELKQLQKKKENLIEELERINNDVVEAQKQLVTQRKKQRSLGAEPQQQDENMEEDIQ 2520

Query: 614  KAISLLESQKFDLVQELHIL-----------QQKYDEVEDKLA--DISQLQSDQVCSEI- 659
              I+ L S+  +L  +L  L            ++  EV+D  A   +SQ   D+V   + 
Sbjct: 2521 DKITSLNSRNNNLKDDLQKLVEMSPEPTERKPEEQQEVKDAPAPVQVSQFAPDRVQQTLQ 2580

Query: 660  ---KSVH-LEEQIDALSASKKELALVIENL---KL--------DKEQLYGTIKDLENDKE 704
               K +  LE  I  L   ++E   +I ++   KL        D + L   ++D    + 
Sbjct: 2581 DRDKKIEILEMTISTLQQQQQERMSMIPSMFQSKLSVQPSFFMDDDPLLLELQDKFTKES 2640

Query: 705  DIMNKLQNYIQENMDLTDKLE---KMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERD 761
            +++  LQN I++  +    L    K  AEK + L  +++   QS  Q +F + A   ++ 
Sbjct: 2641 ELLKDLQNKIKQTAESHYALSLQLKDWAEKENRLAKELDTRRQSVEQIEFELQAVFAKQS 2700

Query: 762  LYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQED 821
                ++ESE      RI  LE       ++  + + K  +   YLQ   K   E   +  
Sbjct: 2701 ----DLESEKVNVLQRIYSLEVETQDFYEQEANTKNKLKEKKDYLQTLYKNLIESDQKLL 2756

Query: 822  ELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVE 881
            +L NR+A+     R + +Q+  +E+E +  Q+  Q +  + +++++   + Q    ++ +
Sbjct: 2757 QLRNRMALYSQEGRQLAEQVENLENEKENKQQHLQDIQADLEHVEMEKQEKQALVQSIAK 2816

Query: 882  KANRT----DLAESESTKYQTQLRDLESNLKRITHEHQTLI----VQKKKE---IEDLEI 930
            + + T    D  E +     ++ + L+S +      +Q L+    + KK++    ++L  
Sbjct: 2817 EISETQQEKDKLEIQYATVHSKNQQLKSQIGYEEAFYQKLLQELEIAKKRDQTKFQNLFS 2876

Query: 931  EFNTQIESAIRDKKVLN---EKYEKNIEYVTQLEAQLQEYKNNI-ENLNMNVEELNKMNL 986
            + +TQ E  +   + L+   + Y    E V QL+   ++    I  N N N+++    N 
Sbjct: 2877 DGSTQTEYDLEQFESLSTCTQLYRITKEDVYQLKENCKQRLIQIYTNENANIQQTINQNK 2936

Query: 987  ELIDKHVQKQQTQSPDYTEQYINEI---NKLNALLKQKDEEIIALNQKINNAQVSYMSMV 1043
             L  K +  QQ        + +N I   ++ ++ L     ++   N K++  Q+ +M   
Sbjct: 2937 HL-QKMIHLQQMIIQIQENENVNLIEFQSRRSSRLGLNVMDLSIYNMKLDLEQIDFMM-- 2993

Query: 1044 SDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEE 1080
               ++KL +       +     ++++Q +  KQ + E
Sbjct: 2994 --NKTKLVEVHVSDNQIVVADTKIARQWIVDKQFDYE 3028



 Score = 97.5 bits (232), Expect = 3e-18
 Identities = 224/1200 (18%), Positives = 494/1200 (41%), Gaps = 106/1200 (8%)

Query: 216  QQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLA 275
            +++   QE+ I  +A   +E +R LK +ES D +   +     +    + +I    S++ 
Sbjct: 28   EELLMNQEHIIWQQAREIEELRRRLKQLESLDFQNEQVLHLQNINVQLKTQIEFLRSQIQ 87

Query: 276  QE---LEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLE 332
            ++   + Q               A+Q +     +   I      +I N   +  +++  E
Sbjct: 88   EKDAMIAQLTSKPVQAASPEILAAQQQLIQQNLQLQNIIGDLQNQILNKDAVIGQLKTQE 147

Query: 333  H-LNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSS 391
              L+  I Q    +++K   +G   +   + S         ++ ++   ++   + ++  
Sbjct: 148  STLDQLIGQLQSNIQSKRNKVGVTQQGNETLSVLNELQQYPEALQDVIERIIQEYRRM-- 205

Query: 392  ETLNQDTDKKINKNEIAKLEMVIQSLNKDL--VDKEYVISEKDTXXXXXXXXXXGKDTLI 449
            + L ++ D +I +N  ++L++  Q  N  +  + K  +   +              D +I
Sbjct: 206  QFLIEEKDIEI-QNLKSRLQLQQQKANDSISEIKKRDISPIRSDQALDLAKQTASMDDMI 264

Query: 450  AQLQ--LEHQQHMEGP---SLIHVGT-NTEDVNEIAKVQEQLKQELNDEIK---DVN--V 498
              L+  L  Q + +      L+ VGT N E   + ++ ++QL + +++ +K   DVN  +
Sbjct: 265  NDLERKLMSQDNRKKELQAKLLEVGTQNVELEKQWSQSKDQLPKSVDELVKQNLDVNDKI 324

Query: 499  KDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQ----KTIDNFSKVSDSN 554
            K+L + L S + ++ Q+  +I+  N N  +++    L  ++ Q     T  N + V D  
Sbjct: 325  KELQKSLLSKQNELDQVQKQINTINDNQQQLQPQQNLNKQEDQVDKVNTSQNRNNVDDLV 384

Query: 555  KEIVRLTEELHHLSQKVAELEEEKGN------------LQLHLVDYDSGR-MIESDVYKK 601
             E  +L + +  L QK+ + + +K +            LQ +L D      ++++D   +
Sbjct: 385  LENQQLEDLIVELQQKLVDKQAQKEDIENEIKKLNISALQQNLKDLQKQHGLLDNDNKNQ 444

Query: 602  MIEMENLAE--TRLKAISL-LESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSE 658
              +++ L E   + K I   L  +  +L  + +  Q +  + E+KLA +   ++  +   
Sbjct: 445  KTQIQQLQEEINQNKEIQQKLSQENKELQDQNNQTQSQIKQQEEKLAQLQDQKNKNLAKL 504

Query: 659  IKS--VHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQE 716
                 + L+E+ +    + K L  +++ L  +  +     + LE +  +I NKLQ   QE
Sbjct: 505  TNDDLLKLQEKFNQTEENNKILEQLVQQLNEELRKQQQDNQPLEEELSNIKNKLQKTEQE 564

Query: 717  NMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKS 776
            N DL  +++++  +  +    ++  +E +K    +   A+ Q+R   +E           
Sbjct: 565  NSDLEQQVQQLEDQLNNFKKQQLQTKESAK--PSYSKSAE-QQRTTPVEKFREPFQNIVD 621

Query: 777  RICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVN-RLAVLMDHDR 835
            +       +  +  + +S +   +   S    KQ  +++   QE + +   L ++ +++ 
Sbjct: 622  KE-EFSFDLGSLNQQDFSSQ---EVTSSPENIKQSQFAKNKTQEGKFITIPLDIIKNYEY 677

Query: 836  VVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTK 895
            ++ ++  EI+    EL  +    +  N       SD Q++ N  +E        E     
Sbjct: 678  LIREKENEIDELKNELANQGLQSIPLNFQTGNMGSDQQENANFQLEATAPNQNNEQNPED 737

Query: 896  YQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIE 955
                L  L+  +K      Q L+ Q ++  +   +    Q +    ++K  ++   +NIE
Sbjct: 738  QGVTLEQLQKTIKTKDDYIQMLLDQIEEMKQFGSLPEEQQKQKLEGNQKRSDDLVRQNIE 797

Query: 956  ---YVTQLEAQLQEYKNNIENLNMNVEELNK-----------MNLELIDKHVQKQQTQSP 1001
                +  LE++L   K   E L   ++E NK             L +++K + ++ + SP
Sbjct: 798  IADIIIDLESKLANRKIENEELKKQLQEANKDYNDQQKRAKMYELYMLNKDLDEEVSLSP 857

Query: 1002 -----DYTEQYINEINKLNALLK-----QKDEEIIAL----NQKINNAQVSYMSMVSDYE 1047
                 D   + + ++N+    L+     QK  + + +     +KI + +    ++++  +
Sbjct: 858  KLQEEDLQNEQLEQLNQQAPELEQPEDPQKQAKKLTIKDKYEKKIKDLKKENRNLIAQLK 917

Query: 1048 S-KLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQD-----DQIKELKETKLT 1101
              + AQ   +    ++E     KQ   S Q++ E    V++Q      D  K  ++ +  
Sbjct: 918  QLRGAQQQDQSNRPQQEDDAKLKQSNPSVQNDNEHPEQVQQQQQPKPIDIQKNTQDLQQQ 977

Query: 1102 FEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQ-----EEEEFIQERSV 1156
            +E  + K   +I    ++ + D   N++            L+ Q     ++ E  Q+   
Sbjct: 978  YEKGLEKQVDLI--QEVQSLQDIIENLEQKVQQKKEAKEQLEAQLCALDKKNESSQQDPQ 1035

Query: 1157 LQE-----QSAKLNTE-LQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTEN 1210
            LQE      ++KL+ E LQ  Y + +Q+  L  +L       Q ++ Q++   EQL  + 
Sbjct: 1036 LQESATMASTSKLDQEALQRQYDQEVQISRLKDQLAD----KQNKLEQMEILKEQLKEKE 1091

Query: 1211 DNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQ 1270
            D L +   ++ S       Q   +  EL    L +   D Q+ E +L  QL     + +Q
Sbjct: 1092 DELKAYKEQIPSIQEYQNQQFLHQQEELVNTELRK---DVQRLEDQLDNQLK-LNKELQQ 1147

Query: 1271 LLDSVQSSTQEETNKI-VTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIED 1329
             +D+   S    + KI +++    S  +++ D  + L   Q+K  +++ +   L   IED
Sbjct: 1148 RMDNQHESAALLSQKIKLSIHDSNSSSSQIIDNRQRLVEKQQKADELVREHLSLDDLIED 1207



 Score = 70.5 bits (165), Expect = 4e-10
 Identities = 122/578 (21%), Positives = 253/578 (43%), Gaps = 71/578 (12%)

Query: 800  DQLGSYLQEKQKAYSEYTIQEDE--LVNRLAVLMDHDRVVE------KQLLEIEHENKEL 851
            +Q  S LQ   K  +  TIQE E  L+N+  ++    R +E      KQL  ++ +N+++
Sbjct: 7    EQCVSKLQGHLKGATA-TIQEIEELLMNQEHIIWQQAREIEELRRRLKQLESLDFQNEQV 65

Query: 852  QKKNQILLEENQNLQISLSDMQQHYNALVEKANR-TDLAESESTKYQTQLRDLESNLKRI 910
                 I ++    ++   S +Q+    + +  ++    A  E    Q QL      L+ I
Sbjct: 66   LHLQNINVQLKTQIEFLRSQIQEKDAMIAQLTSKPVQAASPEILAAQQQLIQQNLQLQNI 125

Query: 911  THEHQTLIVQKKKEIEDLEIEFNT------QIESAIRDKKVLNEKYEKNIEYVTQLEAQL 964
              + Q  I+ K   I  L+ + +T      Q++S I+ K+      ++  E ++ L  +L
Sbjct: 126  IGDLQNQILNKDAVIGQLKTQESTLDQLIGQLQSNIQSKRNKVGVTQQGNETLSVLN-EL 184

Query: 965  QEYKNNIEN-LNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDE 1023
            Q+Y   +++ +   ++E  +M   + +K ++ Q  +S    +Q   + N   + +K++D 
Sbjct: 185  QQYPEALQDVIERIIQEYRRMQFLIEEKDIEIQNLKSRLQLQQ--QKANDSISEIKKRDI 242

Query: 1024 EIIALNQKINNAQ--VSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLD-SKQHNEE 1080
              I  +Q ++ A+   S   M++D E KL     + + ++ ++  V  Q ++  KQ ++ 
Sbjct: 243  SPIRSDQALDLAKQTASMDDMINDLERKLMSQDNRKKELQAKLLEVGTQNVELEKQWSQS 302

Query: 1081 LQILVREQD----------DQIKELKETKLTFEMNIPKTEGMIIS-----------STIE 1119
               L +  D          D+IKEL+++ L+ +  + + +  I +             + 
Sbjct: 303  KDQLPKSVDELVKQNLDVNDKIKELQKSLLSKQNELDQVQKQINTINDNQQQLQPQQNLN 362

Query: 1120 PMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQE--RSVLQEQSAK--LNTELQECYTKI 1175
               D  + V+            L+ Q+ E+ I E  + ++ +Q+ K  +  E+++     
Sbjct: 363  KQEDQVDKVNTSQNRNNVDDLVLENQQLEDLIVELQQKLVDKQAQKEDIENEIKKLNISA 422

Query: 1176 IQ--LETLNTE--LTGHDVVNQ--------EQINQ---LKSKLEQLNTE----NDNLLST 1216
            +Q  L+ L  +  L  +D  NQ        E+INQ   ++ KL Q N E    N+   S 
Sbjct: 423  LQQNLKDLQKQHGLLDNDNKNQKTQIQQLQEEINQNKEIQQKLSQENKELQDQNNQTQSQ 482

Query: 1217 VAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQ 1276
            + +    ++   DQ+   +A+L    L + +  F +TE   ++     +   E+L    Q
Sbjct: 483  IKQQEEKLAQLQDQKNKNLAKLTNDDLLKLQEKFNQTEENNKILEQLVQQLNEELRKQQQ 542

Query: 1277 SST--QEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEK 1312
             +   +EE + I    Q T  +N   D E+ ++ L+++
Sbjct: 543  DNQPLEEELSNIKNKLQKTEQENS--DLEQQVQQLEDQ 578



 Score = 68.5 bits (160), Expect = 1e-09
 Identities = 121/660 (18%), Positives = 279/660 (42%), Gaps = 50/660 (7%)

Query: 961  EAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQ 1020
            E  + + + +++     ++E+ ++ +    +H+  QQ +  +   + + ++  L+     
Sbjct: 7    EQCVSKLQGHLKGATATIQEIEELLMN--QEHIIWQQAREIEELRRRLKQLESLDF---- 60

Query: 1021 KDEEIIALNQKIN---NAQVSYM-SMVSDYESKLAQFTTK-LENMEEEMQRVSKQLLDSK 1075
            ++E+++ L Q IN     Q+ ++ S + + ++ +AQ T+K ++    E+    +QL+   
Sbjct: 61   QNEQVLHL-QNINVQLKTQIEFLRSQIQEKDAMIAQLTSKPVQAASPEILAAQQQLI--- 116

Query: 1076 QHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXX 1135
            Q N +LQ ++ +  +QI   K+  +        T   +I      +    N V       
Sbjct: 117  QQNLQLQNIIGDLQNQILN-KDAVIGQLKTQESTLDQLIGQLQSNIQSKRNKVGVTQQGN 175

Query: 1136 XXXXXXLKVQEEEEFIQE--RSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQ 1193
                   ++Q+  E +Q+    ++QE   ++   ++E   K I+++ L + L        
Sbjct: 176  ETLSVLNELQQYPEALQDVIERIIQEYR-RMQFLIEE---KDIEIQNLKSRLQLQQQKAN 231

Query: 1194 EQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVD-QRGFEIAELWKQHLAQREADFQK 1252
            + I+++K K +     +D  L    +  S      D +R     +  K+ L  +  +   
Sbjct: 232  DSISEIK-KRDISPIRSDQALDLAKQTASMDDMINDLERKLMSQDNRKKELQAKLLEVGT 290

Query: 1253 TEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQ-VTSLQNKLQDKEEHLRNLQE 1311
               EL  Q S  + +  + +D +     +  +KI  +++ + S QN+L   ++ +  + +
Sbjct: 291  QNVELEKQWSQSKDQLPKSVDELVKQNLDVNDKIKELQKSLLSKQNELDQVQKQINTIND 350

Query: 1312 KYADVINQIEILRSEIEDEKV--AFXXXXXXXXXXXXXXXXDLRTENQSY---KQMQEQS 1366
                +  Q  + + E + +KV  +                 DL  E Q     KQ Q++ 
Sbjct: 351  NQQQLQPQQNLNKQEDQVDKVNTSQNRNNVDDLVLENQQLEDLIVELQQKLVDKQAQKED 410

Query: 1367 ILN-INEENAQLKKSSXXXXXXXXXXXXRVN-DAEAKVLELTHQLELKDSEIYQKTHEYT 1424
            I N I + N    + +              N + + ++ +L  ++  ++ EI QK  +  
Sbjct: 411  IENEIKKLNISALQQNLKDLQKQHGLLDNDNKNQKTQIQQLQEEIN-QNKEIQQKLSQEN 469

Query: 1425 ITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILR----LKMHENANHYETMQKES 1480
              L  +N++ ++   Q+ + E+++  L  +K   LA L     LK+ E  N  E   K  
Sbjct: 470  KELQDQNNQTQS---QIKQQEEKLAQLQDQKNKNLAKLTNDDLLKLQEKFNQTEENNKIL 526

Query: 1481 EIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEI 1540
            E    +L+++LN ++ +    N+ + E    ++ ++ KT +  + LE Q   +  L D++
Sbjct: 527  E----QLVQQLNEELRKQQQDNQPLEEELSNIKNKLQKTEQENSDLEQQ---VQQLEDQL 579

Query: 1541 TNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDLAMYMLHQRD 1600
             N +   +   +K     S++   +Q R   ++    +   + V + E    +  L+Q+D
Sbjct: 580  NNFKK--QQLQTKESAKPSYSKSAEQQRTTPVEK-FREPFQNIVDKEEFSFDLGSLNQQD 636


>UniRef50_UPI00006CA483 Cluster: hypothetical protein TTHERM_00497680;
            n=1; Tetrahymena thermophila SB210|Rep: hypothetical
            protein TTHERM_00497680 - Tetrahymena thermophila SB210
          Length = 2240

 Score =  165 bits (400), Expect = 1e-38
 Identities = 262/1311 (19%), Positives = 561/1311 (42%), Gaps = 116/1311 (8%)

Query: 330  LLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQL 389
            L+  L  +I   + + E+ L  +    +   S     S  I ++    + +K+     QL
Sbjct: 180  LVNQLKLEIEVLSNKYEDALERLAASERKTPSQQINNSEQIHQQIDDISVAKIDYLQKQL 239

Query: 390  SSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVIS-EKDTXXXXXXXXXXGKDTL 448
                L  + +K+       K   VI  L KDL  ++     EK              D L
Sbjct: 240  QLSQLQLEKEKE-------KALKVILKLEKDLDGQQSSFDFEKLKLSSQIESLNAINDQL 292

Query: 449  IAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKL--- 505
              Q ++   + ++  S++ +    +D   + K   +  Q L D+I  +N    ++K    
Sbjct: 293  --QKEINKLKSIQKESVL-ISQEKDDAESVVKELRKQNQMLTDQINSLNQNFNLQKQSQD 349

Query: 506  KSAEEQITQLNDEIDAANKNMIKVKS------NHKLKLKQMQKTIDNFSKVSDSNKEIVR 559
            K  ++ +  L ++ +   K ++ +K+      N K +++ +Q    +F  V+ S ++   
Sbjct: 350  KQDKQTLIILQEQTEKFEKEILVLKNQKQEDENLKQQIQLIQLEKSDFLSVNQSLRQNQS 409

Query: 560  LTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLL 619
            + E+   + Q  ++ E EK       V   S +   SD  ++  E+    +   + I +L
Sbjct: 410  VLEDQLQILQSQSQ-ENEK-------VKRSSAK---SDFEREKNELVQNIKNLEQQILVL 458

Query: 620  ESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELA 679
            + Q FD +Q    ++++  +++    +I +    Q   E  +  ++ + D L +SK+E  
Sbjct: 459  KKQNFDDLQNNKKIEEQDLQIQKLKNEIREATIKQQKLEQLNGQIQLECDILRSSKRENE 518

Query: 680  LVIENLKL-------DKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEK--MSAE 730
               E  K        DK+Q+   ++D  N+ + +  +LQ  +   +++   LEK   +  
Sbjct: 519  QSQEQRKQLYEKAINDKDQIIKQLRDTLNENQQMFQQLQTQLNIKIEIIANLEKENQNTR 578

Query: 731  KISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMED 790
            K+ E     + ++  +++TQ  +  +I++++  +E I+S   +       L+E  ++ E 
Sbjct: 579  KLYEDRLTTSQQDFEQLKTQ--LKDQIEQKNKQVEQIQSSFMRDMEL---LKEQFSLKEA 633

Query: 791  RRYSLERKAD----QLGSYLQEKQ---KAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLE 843
             +  ++++AD    QL   ++EKQ   + Y +   ++  L   L         ++++L  
Sbjct: 634  EQLDIQKQADEMRQQLLDVIEEKQSWLQKYEKVFAEQQSLSESLGKSQKECNSLQEKLFS 693

Query: 844  IEH-ENKELQK----KNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQT 898
            +++ E K+L+     KN+I +   Q  Q S + ++Q    + E  N+  L   E+ K  T
Sbjct: 694  LQNVEQKQLEDILKLKNEIQIASGQQGQAS-NQLKQANQKIQELENKIILLNLENQKVIT 752

Query: 899  QLRDLESNLKRITHEHQTLIVQK---KKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIE 955
            +  ++   L +  HE   L  Q    K ++E L+ +   +   +    +V+ +  ++  E
Sbjct: 753  EKEEINFKLNQANHEQDILKKQNEEFKNQLEQLKNQILQEKNKSNEQNQVIQKLQQQAKE 812

Query: 956  YVTQLEA------QLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYIN 1009
                 E        LQ+++    + ++ +E+ N +N++   K + K  +Q  D ++  IN
Sbjct: 813  EEVLKENLMSKIDSLQQFQQKYHDASLQLEQFN-INIQEFQKQI-KDLSQIKDESQIKIN 870

Query: 1010 EINKLNALLKQ---KDEEIIA-LNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQ 1065
            ++N  N    Q   K++E+ + L  ++ + Q+       +  S+      KL+  EE+ Q
Sbjct: 871  KLNSENYEATQQLMKEQELNSTLKGEVQHLQLQITQKNGELSSQYELLNNKLKEYEEKEQ 930

Query: 1066 RVSKQLLDSK-QHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDD 1124
            ++  Q+   K Q  E+ Q L++E+D+   +L    ++ +  + K +     +  E    D
Sbjct: 931  KLLIQISQLKIQDQEQEQKLIKERDELHSKLINLDISTQNIMSKHQEE--RNNYERKLFD 988

Query: 1125 ANNV--DXXXXXXXXXXXXLKVQEEEEFIQERSVL-QEQSAKLNTELQECYTKIIQLETL 1181
             NN+  +             +V  E E ++E +   Q Q ++L  +L+E     I   + 
Sbjct: 989  LNNLCNEAKQQNILSTDKLTQVTRELEQLKETNKQKQNQVSELTLKLEEVTKLKITDSSK 1048

Query: 1182 NTELTGH-DVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWK 1240
              EL    D V QE+  ++K  +E L    D L+++ ++    I+ +  Q    I EL +
Sbjct: 1049 IQELQSQVDFVKQEKDREIKKSIE-LQKNLDGLIASTSQKDQEINLSKIQ----IQELNR 1103

Query: 1241 QHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQE-ETNKIVTMEQVTSLQNKL 1299
            Q L   E     T    + Q+   +  YE+ L  + +  ++ + +K++  E++  L  K 
Sbjct: 1104 QILVSNE-----TIQSYKKQVDNLQESYEKQLSELSTFNEDLKRSKLLDDERIQELTMKT 1158

Query: 1300 QDKEEH--LRNLQ-----EKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDL 1352
               EE   LRN Q     E   +  ++ ++L  ++E EK  F                +L
Sbjct: 1159 SQIEEQMDLRNSQHLQMSEFRKNEEHRFQLLCQQMEIEKQQFLKDIQDLTLKLEKCEKEL 1218

Query: 1353 RTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDA--EAKV---LELTH 1407
              E   +    EQ      EE +QL K              ++     E K+   L+L  
Sbjct: 1219 DEEKNQFIYQLEQ----FREEKSQLLKQIEEEKSIKENTIFQIQQQFEEQKIQFSLKLND 1274

Query: 1408 QLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEK--RIEDLTYEKESELAILRLK 1465
             +  +D  I     E+  +  +   E E++R Q+ E ++   I+ L   ++ E   ++ +
Sbjct: 1275 LMNNQDKHIKSINKEFEESKKRDQLEIESLRNQIDEVKESSNIQILNLSQQLEEVKMQEQ 1334

Query: 1466 MHENANHYETMQKE-----SEIE-RVKLIEELNVKITESVSLNKQVAELNKALEEEVAKT 1519
              +     +T +K+     S++E + + + +L ++I ++     Q+ +    L  +V + 
Sbjct: 1335 EKQMLEQKQTEEKQITNLTSQLEVKSQELTQLKIQIQQNSHFEVQLQDAENKLAGQVQQI 1394

Query: 1520 NEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQ-KHVSFASDTKQGRD 1569
              +Q   +NQ++++  LN +I N Q+ ++  S K     V+F+   ++ ++
Sbjct: 1395 ENLQKINQNQQVQLEQLNLQIQNFQDHIQQKSMKYSTSEVNFSEQIEKQQE 1445



 Score =  140 bits (338), Expect = 4e-31
 Identities = 294/1496 (19%), Positives = 621/1496 (41%), Gaps = 131/1496 (8%)

Query: 143  DVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIE-----AKNKATTXXX 197
            ++  L N  +E +N    +Q+ +++ ++  L + + + +   ++E      ++++     
Sbjct: 369  EILVLKNQKQEDENLKQQIQL-IQLEKSDFLSVNQSLRQNQSVLEDQLQILQSQSQENEK 427

Query: 198  XXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEAN 257
                           +  Q +  +++  + ++ +  D+ Q   K IE +D++I  L+  N
Sbjct: 428  VKRSSAKSDFEREKNELVQNIKNLEQQILVLKKQNFDDLQNN-KKIEEQDLQIQKLK--N 484

Query: 258  KLLEAARFEISLEHSKLAQELE-QXXXXXXXXXXXXXXLAKQSIEPSCEEKTEI------ 310
            ++ EA   +  LE      +LE                  KQ  E +  +K +I      
Sbjct: 485  EIREATIKQQKLEQLNGQIQLECDILRSSKRENEQSQEQRKQLYEKAINDKDQIIKQLRD 544

Query: 311  --EEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSP 368
               E   +     T+L  KIE++ +L  + + T K  E++L T   + + + +  K    
Sbjct: 545  TLNENQQMFQQLQTQLNIKIEIIANLEKENQNTRKLYEDRLTTSQQDFEQLKTQLKDQIE 604

Query: 369  LISRKSGRNTASKMKSP---WSQLSSETLNQ-DTDKKINKNEIAKLEMVIQSLNKDLVDK 424
              +++  +  +S M+       Q S +   Q D  K+ ++     L+ VI+     L   
Sbjct: 605  QKNKQVEQIQSSFMRDMELLKEQFSLKEAEQLDIQKQADEMRQQLLD-VIEEKQSWLQKY 663

Query: 425  EYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQ 484
            E V +E+ +           K+    Q +L   Q++E   L  +    +  NEI     Q
Sbjct: 664  EKVFAEQQSLSESLGKSQ--KECNSLQEKLFSLQNVEQKQLEDI---LKLKNEIQIASGQ 718

Query: 485  LKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTI 544
              Q  N ++K  N     +K++  E +I  LN E    N+ +I  K     KL Q     
Sbjct: 719  QGQASN-QLKQAN-----QKIQELENKIILLNLE----NQKVITEKEEINFKLNQANHEQ 768

Query: 545  DNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIE 604
            D   K ++  K       +L  L  ++ + E+ K N Q  ++     +  E +V K    
Sbjct: 769  DILKKQNEEFK------NQLEQLKNQILQ-EKNKSNEQNQVIQKLQQQAKEEEVLK---- 817

Query: 605  MENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHL 664
             ENL  +++ ++   + +  D   +L        E + ++ D+SQ++ +   S+IK   L
Sbjct: 818  -ENLM-SKIDSLQQFQQKYHDASLQLEQFNINIQEFQKQIKDLSQIKDE---SQIKINKL 872

Query: 665  -EEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDK 723
              E  +A     KE  L    LK + + L   I     +       L N ++E  +   K
Sbjct: 873  NSENYEATQQLMKEQEL-NSTLKGEVQHLQLQITQKNGELSSQYELLNNKLKEYEEKEQK 931

Query: 724  LEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENI----ESELSKYKSRIC 779
            L      +IS+L  +   +EQ  I+ +  + +K+   D+  +NI    + E + Y+ ++ 
Sbjct: 932  L----LIQISQLKIQDQEQEQKLIKERDELHSKLINLDISTQNIMSKHQEERNNYERKLF 987

Query: 780  RL-------EESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMD 832
             L       ++   +  D+   + R+ +QL    ++KQ   SE T++ +E V +L +  D
Sbjct: 988  DLNNLCNEAKQQNILSTDKLTQVTRELEQLKETNKQKQNQVSELTLKLEE-VTKLKI-TD 1045

Query: 833  HDRVVEKQ-LLEIEHENKELQKKNQILLEEN-QNLQISLSDMQQHYN---ALVEKANRTD 887
              ++ E Q  ++   + K+ + K  I L++N   L  S S   Q  N     +++ NR  
Sbjct: 1046 SSKIQELQSQVDFVKQEKDREIKKSIELQKNLDGLIASTSQKDQEINLSKIQIQELNRQI 1105

Query: 888  LAESESTK-YQTQLRDLESNLKRITHEHQTL--IVQKKKEIEDLEIEFNTQIESAIRDKK 944
            L  +E+ + Y+ Q+ +L+ + ++   E  T    +++ K ++D  I+  T   S I ++ 
Sbjct: 1106 LVSNETIQSYKKQVDNLQESYEKQLSELSTFNEDLKRSKLLDDERIQELTMKTSQIEEQM 1165

Query: 945  VLN-------EKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQ 997
             L         ++ KN E+  QL  Q  E +   +    ++++L  + LE  +K + +++
Sbjct: 1166 DLRNSQHLQMSEFRKNEEHRFQLLCQQMEIEK--QQFLKDIQDLT-LKLEKCEKELDEEK 1222

Query: 998  TQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKL 1057
             Q     EQ+  E ++   LLKQ +EE       I   Q  +      +  KL      +
Sbjct: 1223 NQFIYQLEQFREEKSQ---LLKQIEEEKSIKENTIFQIQQQFEEQKIQFSLKLNDL---M 1276

Query: 1058 ENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISST 1117
             N ++ ++ ++K+  +SK+ +   Q+ +    +QI E+KE+     +N+ +    +    
Sbjct: 1277 NNQDKHIKSINKEFEESKKRD---QLEIESLRNQIDEVKESSNIQILNLSQQLEEVKMQE 1333

Query: 1118 IEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKII- 1176
             E    +    +            +K QE    + +  +  +Q++    +LQ+   K+  
Sbjct: 1334 QEKQMLEQKQTEEKQITNLTSQLEVKSQE----LTQLKIQIQQNSHFEVQLQDAENKLAG 1389

Query: 1177 ---QLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGF 1233
               Q+E L  ++  +  V  EQ+N L+ +  Q + +  ++  + +E+  + S  ++++  
Sbjct: 1390 QVQQIENLQ-KINQNQQVQLEQLN-LQIQNFQDHIQQKSMKYSTSEV--NFSEQIEKQQ- 1444

Query: 1234 EIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTME-QV 1292
            E  +  K  +++ E + QK       + +    + E+L  ++Q    +  + I  +  Q+
Sbjct: 1445 EFIDKLKSQVSELELNIQKLNLNSTQEKTKLNLEIEKLNQTIQKQQSDYNSSIYKLNCQI 1504

Query: 1293 TSLQNKL---QDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXX 1349
               +N++   Q +   +++ ++ +     +++   S++   K                  
Sbjct: 1505 EIYKNEINVFQSQNNSIQSSKDTFLKEYEKLQEANSKLVLSKSELEMELEILKNQIQHTQ 1564

Query: 1350 XDLRTENQSYKQMQEQSILNINEENAQLKK-SSXXXXXXXXXXXXRVNDAE-AKVLELTH 1407
                 E + ++Q+ ++ I  I E++ +++   +            + ND   A+ +E   
Sbjct: 1565 QATILEFEGFRQLNDKRIKEILEKDEKIQDLQNQLHQRDIKMLQFKQNDVGLARQIE-DL 1623

Query: 1408 QLELKDSEIYQKTHEYTI-TLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKM 1466
            QL++K+ EI +   + +     +R  + E  +QQ  +  K+I     +  SE   L+ ++
Sbjct: 1624 QLQVKNLEIERNQLQQSYQKFQERIQQLEGQKQQFRDKYKKI---VQQSTSEFLALKSQV 1680

Query: 1467 HENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTAL 1526
               A        +S I      E +N+K+ E ++L  Q  EL KA E   +K  E     
Sbjct: 1681 ENLAKKDANSSIDSSIRYQS--ESINLKMKEELTLKNQ--ELQKAYEFIQSKKQECSVLS 1736

Query: 1527 ENQEIEIVTLNDEI--TNLQNMVRASSSKIQKHVSFASD-TKQGRDEQLDNTMNKE 1579
            +  E+    L  +    +LQN +    ++   H+   +D  KQ     L N +  E
Sbjct: 1737 QQYEVLKQQLEKKAASNSLQNSMEQDGNEELTHLKQENDLLKQKNKTLLQNIVELE 1792



 Score =  138 bits (335), Expect = 9e-31
 Identities = 221/1123 (19%), Positives = 476/1123 (42%), Gaps = 101/1123 (8%)

Query: 235  EKQRLLKDIESKDVRISSLEEANKLLEAARFE---ISLEHSKLAQELEQXXXXXXXXXXX 291
            E + +L ++E++ V I+  EE N  L  A  E   +  ++ +   +LEQ           
Sbjct: 737  ENKIILLNLENQKV-ITEKEEINFKLNQANHEQDILKKQNEEFKNQLEQLKNQILQEKNK 795

Query: 292  XXXLAK--QSIEPSCEEKTEIEEKGSLEIANMTELTKKIE----LLEHLNCQIRQTNKEL 345
                 +  Q ++   +E+  ++E    +I ++ +  +K       LE  N  I++  K++
Sbjct: 796  SNEQNQVIQKLQQQAKEEEVLKENLMSKIDSLQQFQQKYHDASLQLEQFNINIQEFQKQI 855

Query: 346  ENKLATMGTESKA----VSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDT--- 398
            ++ L+ +  ES+     ++S + + +  + ++   N+  K +    QL     N +    
Sbjct: 856  KD-LSQIKDESQIKINKLNSENYEATQQLMKEQELNSTLKGEVQHLQLQITQKNGELSSQ 914

Query: 399  ----DKKINKNEIAKLEMVIQSLNKDLVDKEY---VISEKDTXXXXXXXXXXGKDTLIAQ 451
                + K+ + E  + +++IQ     + D+E    +I E+D               ++++
Sbjct: 915  YELLNNKLKEYEEKEQKLLIQISQLKIQDQEQEQKLIKERDELHSKLINLDISTQNIMSK 974

Query: 452  LQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQ 511
             Q E   +              D+N +    +Q      D++  V  +  +E+LK   +Q
Sbjct: 975  HQEERNNYER---------KLFDLNNLCNEAKQQNILSTDKLTQVTRE--LEQLKETNKQ 1023

Query: 512  ITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSN-KEIVRLTEELHHLSQK 570
                  E+    + + K+K     K++++Q  +D   +  D   K+ + L + L  L   
Sbjct: 1024 KQNQVSELTLKLEEVTKLKITDSSKIQELQSQVDFVKQEKDREIKKSIELQKNLDGLIAS 1083

Query: 571  VAELEEEKGNLQLHLVDYDSGRMIESDV---YKKMIEMENLAETRLKAISLLESQKFDLV 627
             ++ ++E    ++ + + +   ++ ++    YKK ++  NL E+  K +S L +   DL 
Sbjct: 1084 TSQKDQEINLSKIQIQELNRQILVSNETIQSYKKQVD--NLQESYEKQLSELSTFNEDLK 1141

Query: 628  -------QELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQI--DALSASKKEL 678
                   + +  L  K  ++E+++ D+   Q  Q+    K+     Q+    +   K++ 
Sbjct: 1142 RSKLLDDERIQELTMKTSQIEEQM-DLRNSQHLQMSEFRKNEEHRFQLLCQQMEIEKQQF 1200

Query: 679  ALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAK 738
               I++L L  E+     K+L+ +K   + +L+ + +E   L  ++E+  + K + +   
Sbjct: 1201 LKDIQDLTLKLEKCE---KELDEEKNQFIYQLEQFREEKSQLLKQIEEEKSIKENTIFQI 1257

Query: 739  INHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERK 798
                E+ KIQ    ++  +  +D +I++I  E  + K R  +LE     +E  R  ++  
Sbjct: 1258 QQQFEEQKIQFSLKLNDLMNNQDKHIKSINKEFEESKKR-DQLE-----IESLRNQIDEV 1311

Query: 799  ADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQIL 858
             +     +    +   E  +QE E    L      ++ +     ++E +++EL +  +I 
Sbjct: 1312 KESSNIQILNLSQQLEEVKMQEQE-KQMLEQKQTEEKQITNLTSQLEVKSQELTQL-KIQ 1369

Query: 859  LEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLI 918
            +++N + ++ L D +   N L  +  + +  +  +   Q QL  L   ++      Q  I
Sbjct: 1370 IQQNSHFEVQLQDAE---NKLAGQVQQIENLQKINQNQQVQLEQLNLQIQNF----QDHI 1422

Query: 919  VQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMN- 977
             QK  +    E+ F+ QI              EK  E++ +L++Q+ E + NI+ LN+N 
Sbjct: 1423 QQKSMKYSTSEVNFSEQI--------------EKQQEFIDKLKSQVSELELNIQKLNLNS 1468

Query: 978  VEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQV 1037
             +E  K+NLE I+K  Q  Q Q  DY     + I KLN  ++    EI     + N+ Q 
Sbjct: 1469 TQEKTKLNLE-IEKLNQTIQKQQSDYN----SSIYKLNCQIEIYKNEINVFQSQNNSIQS 1523

Query: 1038 SYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQI--KEL 1095
            S  + + +YE KL +  +KL   + E++   + L +  QH ++  IL  E   Q+  K +
Sbjct: 1524 SKDTFLKEYE-KLQEANSKLVLSKSELEMELEILKNQIQHTQQATILEFEGFRQLNDKRI 1582

Query: 1096 KETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQ-EEEEFIQER 1154
            KE  L  +  I   +  +    I+ +    N+V               ++ E  +  Q  
Sbjct: 1583 KEI-LEKDEKIQDLQNQLHQRDIKMLQFKQNDVGLARQIEDLQLQVKNLEIERNQLQQSY 1641

Query: 1155 SVLQEQSAKLNTELQEC---YTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTEND 1211
               QE+  +L  + Q+    Y KI+Q  T         V N  + +   S    +  +++
Sbjct: 1642 QKFQERIQQLEGQKQQFRDKYKKIVQQSTSEFLALKSQVENLAKKDANSSIDSSIRYQSE 1701

Query: 1212 NLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQL 1271
            ++   + E   ++ +   Q+ +E  +  KQ  +     ++  + +L  + ++   +    
Sbjct: 1702 SINLKMKE-ELTLKNQELQKAYEFIQSKKQECSVLSQQYEVLKQQLEKKAASNSLQNSME 1760

Query: 1272 LDSVQSSTQ-EETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKY 1313
             D  +  T  ++ N ++  +  T LQN + + E   ++ Q+ Y
Sbjct: 1761 QDGNEELTHLKQENDLLKQKNKTLLQN-IVELETKQKSQQQMY 1802



 Score = 96.3 bits (229), Expect = 6e-18
 Identities = 219/1088 (20%), Positives = 425/1088 (39%), Gaps = 129/1088 (11%)

Query: 212  EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDI-ESKDVRISSLEEANKLLEAARFEISLE 270
            E  ++++ + +  FI    ++++EK +LLK I E K ++ +++ +  +  E  + + SL+
Sbjct: 1212 EKCEKELDEEKNQFIYQLEQFREEKSQLLKQIEEEKSIKENTIFQIQQQFEEQKIQFSLK 1271

Query: 271  HSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIEL 330
             + L    ++                +  IE    +  E++E  +++I N+++  +++++
Sbjct: 1272 LNDLMNNQDKHIKSINKEFEESKKRDQLEIESLRNQIDEVKESSNIQILNLSQQLEEVKM 1331

Query: 331  LEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLS 390
             E     + Q  K+ E K  T  T    V S  +     I  +   +   +++   ++L+
Sbjct: 1332 QEQEKQMLEQ--KQTEEKQITNLTSQLEVKS-QELTQLKIQIQQNSHFEVQLQDAENKLA 1388

Query: 391  SETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIA 450
             +    +  +KIN+N+  +LE     LN  + + +  I +K                   
Sbjct: 1389 GQVQQIENLQKINQNQQVQLE----QLNLQIQNFQDHIQQKSMKYSTSEVNFSE------ 1438

Query: 451  QLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKS-AE 509
              Q+E QQ         V     ++ ++     Q K +LN EI+ +N    I+K +S   
Sbjct: 1439 --QIEKQQEFIDKLKSQVSELELNIQKLNLNSTQEKTKLNLEIEKLN--QTIQKQQSDYN 1494

Query: 510  EQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKT-IDNFSKVSDSNKEIVRLTEELHHLS 568
              I +LN +I+   KN I V  +    ++  + T +  + K+ ++N ++V    EL    
Sbjct: 1495 SSIYKLNCQIE-IYKNEINVFQSQNNSIQSSKDTFLKEYEKLQEANSKLVLSKSELE--- 1550

Query: 569  QKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQ 628
                ELE  K  +Q H        ++E + +++      L + R+K I   + +  DL  
Sbjct: 1551 ---MELEILKNQIQ-HT---QQATILEFEGFRQ------LNDKRIKEILEKDEKIQDLQN 1597

Query: 629  ELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLD 688
            +LH   Q+         DI  LQ  Q       V L  QI+       +L L ++NL+++
Sbjct: 1598 QLH---QR---------DIKMLQFKQ-----NDVGLARQIE-------DLQLQVKNLEIE 1633

Query: 689  KEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLA-KINHEEQSKI 747
            + Q       L+   +    ++Q    +     DK +K+  +  SE LA K   E  +K 
Sbjct: 1634 RNQ-------LQQSYQKFQERIQQLEGQKQQFRDKYKKIVQQSTSEFLALKSQVENLAKK 1686

Query: 748  QTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQ 807
                 ID+ I+ +       ES   K K  +    + +     + Y   +   Q  S L 
Sbjct: 1687 DANSSIDSSIRYQS------ESINLKMKEELTLKNQEL----QKAYEFIQSKKQECSVLS 1736

Query: 808  EKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQI 867
            ++ +   +  +++    N L   M+ D    ++L  ++ EN  L++KN+ LL+    L+ 
Sbjct: 1737 QQYEVLKQ-QLEKKAASNSLQNSMEQDG--NEELTHLKQENDLLKQKNKTLLQNIVELET 1793

Query: 868  SLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKR---ITHEHQTLIVQKKKE 924
                 QQ Y          D  +S  +  Q      E N+K+    T +  T   + K+ 
Sbjct: 1794 KQKSQQQMYTQSDSIDKYQDTQQSGFSMKQDNYIFTEQNIKQAPIATQQSSTSSTKIKQS 1853

Query: 925  IED---LEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEEL 981
            + +     I      E+   + K++       +    Q   Q    +NN           
Sbjct: 1854 LVNPYHHYIPLPPTTETQRNNNKIIYSIINNQVPNNDQRYQQKMGIRNNNSPYQQKQSGY 1913

Query: 982  NKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMS 1041
            NK+       +  K Q  +   ++   N          QK      + Q+++    S +S
Sbjct: 1914 NKLRGIGQTSNTPKNQGSNTPRSKSQNN---------PQK------IQQELDQLNASGVS 1958

Query: 1042 MVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLT 1101
                Y+ K    T ++  ++EE +++ KQ       NE L+ L  E   Q+ EL  +KL 
Sbjct: 1959 PTEFYKVKCQLLTEQMAFVQEESEKLKKQ-------NEHLRTLNFEYVKQLNELSASKLR 2011

Query: 1102 FEMNIPKTEGMIISSTIEPMSDD-----ANNVDXXXXXXXXXXXXLKVQE---------- 1146
                I  T     S +I     D     ANN               ++ E          
Sbjct: 2012 AAEKIIITPEFFESDSINQKVKDFMRKLANNYKLLEKEQTKLVDHCRIMEQDIENYRIKV 2071

Query: 1147 -EEEFIQE--RSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKL 1203
             E + I E  +   Q     L   L++   K+  L   + EL+    +  E+I+ L+S +
Sbjct: 2072 IEADQITEKLKQTGQHSIDSLVQSLKDSEDKVESLSQHSKELSLELAIKLEKISNLESNI 2131

Query: 1204 EQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSA 1263
            + LN E D+  +   +L +  +  + Q   E      + + + +    + EHE R+    
Sbjct: 2132 QDLNNEIDDHKNEYQKLMTKYNKMISQNE-EKKNFDHKQIYELQLKCGQLEHESRLLQGT 2190

Query: 1264 FESKYEQL 1271
             +++  QL
Sbjct: 2191 LQNQNVQL 2198



 Score = 69.3 bits (162), Expect = 8e-10
 Identities = 254/1378 (18%), Positives = 517/1378 (37%), Gaps = 125/1378 (9%)

Query: 90   ISESLANTLKQKEILMEKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSN 149
            I++       Q E+L  K+K+Y+E  ++    I +               +    + L N
Sbjct: 904  ITQKNGELSSQYELLNNKLKEYEEKEQKLLIQISQLKIQDQEQEQKLIKERDELHSKLIN 963

Query: 150  TIKEKDNALSVLQVKMKIMETTILDLQEKINE-KDQIIEAKNKATTXXXXXXXXXXXXXX 208
                  N +S  Q +    E  + DL    NE K Q I + +K T               
Sbjct: 964  LDISTQNIMSKHQEERNNYERKLFDLNNLCNEAKQQNILSTDKLTQVTRELEQLKETNKQ 1023

Query: 209  XXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIE----SKDVRISSLEEANKLLEAAR 264
               ++   ++T   E    ++     + Q L   ++     KD  I    E  K L+   
Sbjct: 1024 K--QNQVSELTLKLEEVTKLKITDSSKIQELQSQVDFVKQEKDREIKKSIELQKNLDGLI 1081

Query: 265  FEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTEL 324
               S +  ++     Q              +  QS +   +   E  EK   E++   E 
Sbjct: 1082 ASTSQKDQEINLSKIQIQELNRQILVSNETI--QSYKKQVDNLQESYEKQLSELSTFNED 1139

Query: 325  TKKIELLEHLNCQ-IRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMK 383
             K+ +LL+    Q +     ++E ++    ++   +S   K           +    +M+
Sbjct: 1140 LKRSKLLDDERIQELTMKTSQIEEQMDLRNSQHLQMSEFRKN-----EEHRFQLLCQQME 1194

Query: 384  SPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXX 443
                Q   +   QD   K+ K E    + + +  N+ +   E    EK            
Sbjct: 1195 IEKQQFLKDI--QDLTLKLEKCE----KELDEEKNQFIYQLEQFREEKSQLLKQIEEEKS 1248

Query: 444  GKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIE 503
             K+  I Q+Q + ++     SL         +N++   Q++  + +N E ++   +D +E
Sbjct: 1249 IKENTIFQIQQQFEEQKIQFSL--------KLNDLMNNQDKHIKSINKEFEESKKRDQLE 1300

Query: 504  KLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEE 563
             ++S   QI    DE+  ++   I   S    ++K  ++      +     K+I  LT +
Sbjct: 1301 -IESLRNQI----DEVKESSNIQILNLSQQLEEVKMQEQEKQMLEQKQTEEKQITNLTSQ 1355

Query: 564  LHHLSQKVAELE---EEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLE 620
            L   SQ++ +L+   ++  + ++ L D       E+ +  ++ ++ENL +         +
Sbjct: 1356 LEVKSQELTQLKIQIQQNSHFEVQLQD------AENKLAGQVQQIENLQKIN-------Q 1402

Query: 621  SQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELAL 680
            +Q+  L Q    +Q   D ++ K    S   + +V    +    +E ID L +   EL L
Sbjct: 1403 NQQVQLEQLNLQIQNFQDHIQQKSMKYS---TSEVNFSEQIEKQQEFIDKLKSQVSELEL 1459

Query: 681  VIENLKLDKEQLYGTIK-DLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKI 739
             I+ L L+  Q    +  ++E   + I  +  +Y      L  ++E    E    +    
Sbjct: 1460 NIQKLNLNSTQEKTKLNLEIEKLNQTIQKQQSDYNSSIYKLNCQIEIYKNE--INVFQSQ 1517

Query: 740  NHEEQSKIQTQFGIDAKIQERD----LYIENIESELSKYKSRICRLEES-IAVMEDRRYS 794
            N+  QS   T      K+QE +    L    +E EL   K++I   +++ I   E  R  
Sbjct: 1518 NNSIQSSKDTFLKEYEKLQEANSKLVLSKSELEMELEILKNQIQHTQQATILEFEGFRQL 1577

Query: 795  LERKADQL---GSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKEL 851
             +++  ++      +Q+ Q    +  I+  +       L      ++ Q+  +E E  +L
Sbjct: 1578 NDKRIKEILEKDEKIQDLQNQLHQRDIKMLQFKQNDVGLARQIEDLQLQVKNLEIERNQL 1637

Query: 852  QKKNQILLEENQNLQISLSDMQQHYNALVE---------KANRTDLAESE-------STK 895
            Q+  Q   E  Q L+      +  Y  +V+         K+   +LA+ +       S +
Sbjct: 1638 QQSYQKFQERIQQLEGQKQQFRDKYKKIVQQSTSEFLALKSQVENLAKKDANSSIDSSIR 1697

Query: 896  YQTQLRDLESNLKRITHEHQTL------IVQKKKEIEDLEIEFNT---QIESAIRDKKVL 946
            YQ++  +L+   + +T ++Q L      I  KK+E   L  ++     Q+E       + 
Sbjct: 1698 YQSESINLKMK-EELTLKNQELQKAYEFIQSKKQECSVLSQQYEVLKQQLEKKAASNSLQ 1756

Query: 947  NEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQ 1006
            N   +   E +T L+ +    K   + L  N+ EL          + Q         T+Q
Sbjct: 1757 NSMEQDGNEELTHLKQENDLLKQKNKTLLQNIVELETKQKSQQQMYTQSDSIDKYQDTQQ 1816

Query: 1007 YINEINKLNALLKQKD--EEIIALNQKINNAQVSYMSMVSDYESKLA---QFTTKLENME 1061
                + + N +  +++  +  IA  Q   ++     S+V+ Y   +       T+  N +
Sbjct: 1817 SGFSMKQDNYIFTEQNIKQAPIATQQSSTSSTKIKQSLVNPYHHYIPLPPTTETQRNNNK 1876

Query: 1062 EEMQRVSKQLLDSKQ-HNEELQILVREQDDQIKELKETKLTF---EMNIPKTEGMIISST 1117
                 ++ Q+ ++ Q + +++ I       Q K+    KL       N PK +G   S+T
Sbjct: 1877 IIYSIINNQVPNNDQRYQQKMGIRNNNSPYQQKQSGYNKLRGIGQTSNTPKNQG---SNT 1933

Query: 1118 IEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQ 1177
              P S   NN                V   E +  +  +L EQ A +  E ++   +   
Sbjct: 1934 --PRSKSQNNPQKIQQELDQLNAS-GVSPTEFYKVKCQLLTEQMAFVQEESEKLKKQNEH 1990

Query: 1178 LETLNTELTGHDVVNQEQINQLKSKLEQLNT----ENDNLLSTVAELRSSISSAVDQRGF 1233
            L TLN E      +N+   ++L++  + + T    E+D++   V +    +++      +
Sbjct: 1991 LRTLNFEYVKQ--LNELSASKLRAAEKIIITPEFFESDSINQKVKDFMRKLAN-----NY 2043

Query: 1234 EIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTME-QV 1292
            ++ E  +  L       ++     R+++   +   E+L  + Q S       +   E +V
Sbjct: 2044 KLLEKEQTKLVDHCRIMEQDIENYRIKVIEADQITEKLKQTGQHSIDSLVQSLKDSEDKV 2103

Query: 1293 TSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDL 1352
             SL    ++    L    EK +++ + I+ L +EI+D K  +                 +
Sbjct: 2104 ESLSQHSKELSLELAIKLEKISNLESNIQDLNNEIDDHKNEY--------QKLMTKYNKM 2155

Query: 1353 RTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLE 1410
             ++N+  K    + I  +  +  QL+  S            ++N  + K+ +L+ + E
Sbjct: 2156 ISQNEEKKNFDHKQIYELQLKCGQLEHESRLLQGTLQNQNVQLNHLDIKIKDLSIENE 2213



 Score = 55.2 bits (127), Expect = 1e-05
 Identities = 175/927 (18%), Positives = 375/927 (40%), Gaps = 106/927 (11%)

Query: 220  KMQENFIAM-EAEWKDEKQ--RLLKDIESKDVRISSLEEANKLLEAARFEISLE--HSKL 274
            KMQE    M E +  +EKQ   L   +E K   ++ L+   ++ + + FE+ L+   +KL
Sbjct: 1330 KMQEQEKQMLEQKQTEEKQITNLTSQLEVKSQELTQLKI--QIQQNSHFEVQLQDAENKL 1387

Query: 275  AQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHL 334
            A +++Q              L + +++     +  I++K      +    +++IE  +  
Sbjct: 1388 AGQVQQIENLQKINQNQQVQLEQLNLQIQ-NFQDHIQQKSMKYSTSEVNFSEQIEKQQEF 1446

Query: 335  NCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETL 394
              +++    ELE  +  +      ++S  +K    +  +    T  K +S ++  S   L
Sbjct: 1447 IDKLKSQVSELELNIQKLN-----LNSTQEKTKLNLEIEKLNQTIQKQQSDYNS-SIYKL 1500

Query: 395  NQDTDKKINKNEIAKLEMVIQSL--NKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQL 452
            N   +  I KNEI   +    S+  +KD   KEY   ++              +  I + 
Sbjct: 1501 NCQIE--IYKNEINVFQSQNNSIQSSKDTFLKEYEKLQEANSKLVLSKSELEMELEILKN 1558

Query: 453  QLEHQQH-----MEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKD----LIE 503
            Q++H Q       EG   ++     E + +  K+Q+   Q    +IK +  K     L  
Sbjct: 1559 QIQHTQQATILEFEGFRQLNDKRIKEILEKDEKIQDLQNQLHQRDIKMLQFKQNDVGLAR 1618

Query: 504  KLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSK-VSDSNKEIVRLTE 562
            +++  + Q+  L  E +   ++  K +   +    Q Q+  D + K V  S  E + L  
Sbjct: 1619 QIEDLQLQVKNLEIERNQLQQSYQKFQERIQQLEGQKQQFRDKYKKIVQQSTSEFLALKS 1678

Query: 563  ELHHLSQKVAE--------LEEEKGNLQLH------------LVDYDSGRMIESDVYKKM 602
            ++ +L++K A          + E  NL++               ++   +  E  V  + 
Sbjct: 1679 QVENLAKKDANSSIDSSIRYQSESINLKMKEELTLKNQELQKAYEFIQSKKQECSVLSQQ 1738

Query: 603  IE-MENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDK----LADISQLQS----- 652
             E ++   E +  + SL  S + D  +EL  L+Q+ D ++ K    L +I +L++     
Sbjct: 1739 YEVLKQQLEKKAASNSLQNSMEQDGNEELTHLKQENDLLKQKNKTLLQNIVELETKQKSQ 1798

Query: 653  DQVCSEIKSV--HLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKL 710
             Q+ ++  S+  + + Q    S  +       +N+K        +       K+ ++N  
Sbjct: 1799 QQMYTQSDSIDKYQDTQQSGFSMKQDNYIFTEQNIKQAPIATQQSSTSSTKIKQSLVNPY 1858

Query: 711  QNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGI---DAKIQERDL---YI 764
             +YI   +  T + ++ + + I  ++         + Q + GI   ++  Q++      +
Sbjct: 1859 HHYIP--LPPTTETQRNNNKIIYSIINNQVPNNDQRYQQKMGIRNNNSPYQQKQSGYNKL 1916

Query: 765  ENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELV 824
              I    +  K++      S +  ++    ++++ DQL +      + Y    ++   L 
Sbjct: 1917 RGIGQTSNTPKNQGSNTPRSKS--QNNPQKIQQELDQLNASGVSPTEFYK---VKCQLLT 1971

Query: 825  NRLAVLMDHDRVVEKQLLEIEHEN----KELQKKNQILLEENQNLQISL----SD-MQQH 875
             ++A + +    ++KQ   +   N    K+L + +   L   + + I+     SD + Q 
Sbjct: 1972 EQMAFVQEESEKLKKQNEHLRTLNFEYVKQLNELSASKLRAAEKIIITPEFFESDSINQK 2031

Query: 876  YNALVEK-ANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNT 934
                + K AN   L E E TK     R +E +++     ++  +++  +  E L+     
Sbjct: 2032 VKDFMRKLANNYKLLEKEQTKLVDHCRIMEQDIEN----YRIKVIEADQITEKLKQTGQH 2087

Query: 935  QIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQ 994
             I+S ++  K   +K E   ++  +L  +L      I NL  N+++LN            
Sbjct: 2088 SIDSLVQSLKDSEDKVESLSQHSKELSLELAIKLEKISNLESNIQDLN------------ 2135

Query: 995  KQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFT 1054
                +  D+  +Y   + K N ++ Q +E+    +++I   Q+    +  ++ES+L Q T
Sbjct: 2136 ---NEIDDHKNEYQKLMTKYNKMISQNEEKKNFDHKQIYELQLKCGQL--EHESRLLQGT 2190

Query: 1055 TKLENMEEEMQRVSKQLLDSKQHNEEL 1081
              L+N   ++  +  ++ D    NE L
Sbjct: 2191 --LQNQNVQLNHLDIKIKDLSIENESL 2215


>UniRef50_Q4LE75 Cluster: CENPE variant protein; n=9;
            Euteleostomi|Rep: CENPE variant protein - Homo sapiens
            (Human)
          Length = 2585

 Score =  165 bits (400), Expect = 1e-38
 Identities = 278/1364 (20%), Positives = 594/1364 (43%), Gaps = 136/1364 (9%)

Query: 297  KQSIEPSCEEKTEIEEKGSLEIANM----TELTKKIELLEHLNCQIRQT-----NKELEN 347
            K+ +E   +EK +++E  +LE         EL+ K+ELL     QI++      +++LEN
Sbjct: 526  KEEMELKLKEKNDLDEFEALERKTKKDQENELSSKVELLREKEDQIKKLQEYIDSQKLEN 585

Query: 348  KLATMGTESKAVSSPSKKGSPLISRKS----GRNTASKMKSPWSQLSSETLNQDTDKKIN 403
                +    +++  P +    L   ++     +  ++ ++S   +L  +     T  K  
Sbjct: 586  IKMDLSYSLESIEDPKQMKQTLFDAETVALDAKRESAFLRSENLELKEKMKELATTYKQM 645

Query: 404  KNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGK--DTLIAQLQLE------ 455
            +N+I   +  +++  K  VD E  +               GK    L+  L+LE      
Sbjct: 646  ENDIQLYQSQLEAKKKMQVDLEKELQSAFNEITKLTSLIDGKVPKDLLCNLELEGKITDL 705

Query: 456  ----HQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNV----KD-LIEKLK 506
                +++  E  +L        ++  +    E+L++E+ D+ +++++    KD L  ++ 
Sbjct: 706  QKELNKEVEENEALREEVILLSELKSLPSEVERLRKEIQDKSEELHIITSEKDKLFSEVV 765

Query: 507  SAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQ--KTI--DNFSKVSDSNKEIVRLTE 562
              E ++  L +EI     ++   +SN+K   ++ Q  KT+  D   K     +E  R+ +
Sbjct: 766  HKESRVQGLLEEIGKTKDDLATTQSNYKSTDQEFQNFKTLHMDFEQKYKMVLEENERMNQ 825

Query: 563  ELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIES--DVYKKMIEMENLAETRLKAISLLE 620
            E+ +LS++  + +   G L+  L  Y +  + E   +V +++ EME L E      S L+
Sbjct: 826  EIVNLSKEAQKFDSSLGALKTEL-SYKTQELQEKTREVQERLNEMEQLKEQLENRDSTLQ 884

Query: 621  SQKFDLVQELHILQQKYDEVE---DKLADISQLQSD-QVCSEIKSVHLEEQIDALSASKK 676
            + + +       LQQ  +EV+    +  D+ QLQ   Q+  +     + + ++    +++
Sbjct: 885  TVEREKTLITEKLQQTLEEVKTLTQEKDDLKQLQESLQIERDQLKSDIHDTVNMNIDTQE 944

Query: 677  ELALVIENLKLDKEQLYGTIKDLENDK-------EDIMNKLQNYIQENMDLTDKLEKMSA 729
            +L   +E+LK  +E +  T+K   +++       E+   + ++  Q+ M   DK + + A
Sbjct: 945  QLRNALESLKQHQETI-NTLKSKISEEVSRNLHMEENTGETKDEFQQKMVGIDKKQDLEA 1003

Query: 730  EKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVME 789
            +    L A +   E   I+ Q  I + IQE++   + +ES +++ +     L+E+I +  
Sbjct: 1004 KNTQTLTADVKDNEI--IEQQRKIFSLIQEKNELQQMLESVIAEKEQLKTDLKENIEMTI 1061

Query: 790  DRRYSLERKADQLGSYLQEKQKAYSEYTIQEDEL---VNRLAVLMDH-----DRVVEKQ- 840
            + +  L    D+L    +   +  +    +E EL    +RLA + +       ++ EKQ 
Sbjct: 1062 ENQEELRLLGDELKKQQEIVAQEKNHAIKKEGELSRTCDRLAEVEEKLKEKSQQLQEKQQ 1121

Query: 841  -LLEIEHENKELQKK-NQI--LLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKY 896
             LL ++ E  E+QKK N+I  L  E +N +++L  M+     L +K N         TK 
Sbjct: 1122 QLLNVQEEMSEMQKKINEIENLKNELKNKELTLEHMETERLELAQKLNENYEEVKSITKE 1181

Query: 897  QTQLRDLESN-------LKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEK 949
            +  L++L+ +       L+    E +   +Q K+E++   I      E+    ++ ++EK
Sbjct: 1182 RKVLKELQKSFETERDHLRGYIREIEATGLQTKEELKIAHIHLKEHQETIDELRRSVSEK 1241

Query: 950  YEK--NIEYVTQLEAQLQE---YKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYT 1004
              +  N + + +   +LQE     +  + L  NV+E+++    + +  +  +Q+ + D T
Sbjct: 1242 TAQIINTQDLEKSHTKLQEEIPVLHEEQELLPNVKEVSETQETMNELELLTEQSTTKDST 1301

Query: 1005 EQYINEINKL--NALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEE 1062
                 E+ +L  N   ++  EEI +L ++ +N +    ++   ++         L  ++E
Sbjct: 1302 TLARIEMERLRLNEKFQESQEEIKSLTKERDNLKTIKEALEVKHDQLKEHIRETLAKIQE 1361

Query: 1063 EMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMS 1122
               +  +Q L+ K+ + E   +V E + Q K      L  E+     E + +S  ++   
Sbjct: 1362 SQSK-QEQSLNMKEKDNETTKIVSEME-QFKPKDSALLRIEI-----EMLGLSKRLQESH 1414

Query: 1123 DDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLN 1182
            D+  +V                +E+++  + + VLQ +S +L   ++E   K   LET  
Sbjct: 1415 DEMKSV---------------AKEKDDLQRLQEVLQSESDQLKENIKEIVAK--HLETEE 1457

Query: 1183 TELTGHDVVNQEQ--INQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWK 1240
                 H  + +++  IN+L+  L +  TE    +ST+ +   +I+  +  +  EI E  +
Sbjct: 1458 ELKVAHCCLKEQEETINELRVNLSEKETE----ISTIQKQLEAINDKLQNKIQEIYEKEE 1513

Query: 1241 QHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQ 1300
            Q   ++ ++ Q+  +EL+ Q        +  L S++S   E TN++   E    +Q  ++
Sbjct: 1514 QFNIKQISEVQEKVNELK-QFKEHRKAKDSALQSIESKMLELTNRL--QESQEEIQIMIK 1570

Query: 1301 DKEEHLRNLQEKYADVINQI-----EILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTE 1355
            +KEE ++ +QE      +Q+     EI+    E ++  +                ++   
Sbjct: 1571 EKEE-MKRVQEALQIERDQLKENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEHL 1629

Query: 1356 NQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSE 1415
             + + + Q+ ++ NI  EN +L +                +D  +    +   L+++  +
Sbjct: 1630 KEQF-ETQKLNLENIETENIRLTQILHENLEEMRSVTKERDDLRS----VEETLKVERDQ 1684

Query: 1416 IYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDL---TYEKESELAILRLKMHENANH 1472
            + +   E      ++ +E + V   L E+++ I+ L     EK +E++     M ++  H
Sbjct: 1685 LKENLRETITRDLEKQEELKIVHMHLKEHQETIDKLRGIVSEKTNEIS----NMQKDLEH 1740

Query: 1473 YETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIE 1532
                 K  ++   K+ EEL +         + + +L   + E+  K + MQ  LEN   +
Sbjct: 1741 SNDALKAQDL---KIQEELRIAHMHLKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAK 1797

Query: 1533 IVTLNDEI-TNLQNMV--RASSSKIQKHVSFASD-TKQGRDEQL 1572
            +     E+  N   ++  +   ++ QK VS      KQ +D+ L
Sbjct: 1798 LQEKIQELKANEHQLITLKKDVNETQKKVSEMEQLKKQIKDQSL 1841



 Score =  132 bits (320), Expect = 6e-29
 Identities = 318/1563 (20%), Positives = 670/1563 (42%), Gaps = 193/1563 (12%)

Query: 91   SESLANTLKQKEILMEKIKQYKE-LSKRSSTT-IVRXXXXXXXXXXXXXXXQLGDVTHLS 148
            ++ L    ++ +  + +++Q KE L  R ST   V                ++  +T   
Sbjct: 852  TQELQEKTREVQERLNEMEQLKEQLENRDSTLQTVEREKTLITEKLQQTLEEVKTLTQEK 911

Query: 149  NTIKEKDNALSVL--QVKMKIMETTIL--DLQEKINEKDQIIEAKNKATTXXXXXXXXXX 204
            + +K+   +L +   Q+K  I +T  +  D QE++    + ++   +             
Sbjct: 912  DDLKQLQESLQIERDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQETINTLKSKISEEV 971

Query: 205  XXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLE-EANKLLEAA 263
                   E+T +   + Q+  + +     D+KQ    D+E+K+ +  + + + N+++E  
Sbjct: 972  SRNLHMEENTGETKDEFQQKMVGI-----DKKQ----DLEAKNTQTLTADVKDNEIIEQQ 1022

Query: 264  RFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEI-----EEKGSLEI 318
            R   SL   K   EL+Q                K++IE + E + E+     E K   EI
Sbjct: 1023 RKIFSLIQEK--NELQQMLESVIAEKEQLKTDLKENIEMTIENQEELRLLGDELKKQQEI 1080

Query: 319  ANMT---------ELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPL 369
                         EL++  + L  +  ++++ +++L+ K   +    + +S   KK + +
Sbjct: 1081 VAQEKNHAIKKEGELSRTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEI 1140

Query: 370  ISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKN-----EIAKLEMVIQSLNKDL-VD 423
             + K   N     +     + +E L  +  +K+N+N      I K   V++ L K    +
Sbjct: 1141 ENLK---NELKNKELTLEHMETERL--ELAQKLNENYEEVKSITKERKVLKELQKSFETE 1195

Query: 424  KEYVISEKDTXXXXXXXXXXGKDTL-IAQLQL-EHQQHM-EGPSLIHVGT----NTEDVN 476
            ++++   +             K+ L IA + L EHQ+ + E    +   T    NT+D+ 
Sbjct: 1196 RDHL---RGYIREIEATGLQTKEELKIAHIHLKEHQETIDELRRSVSEKTAQIINTQDLE 1252

Query: 477  EI-AKVQEQL-----KQELNDEIKDVN-VKDLIEKLKSAEEQITQLNDEIDAANKNMIKV 529
            +   K+QE++     +QEL   +K+V+  ++ + +L+   EQ T   D    A   M ++
Sbjct: 1253 KSHTKLQEEIPVLHEEQELLPNVKEVSETQETMNELELLTEQSTT-KDSTTLARIEMERL 1311

Query: 530  KSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELH-----HLSQKVAELEEEKGNLQLH 584
            + N K +  + Q+ I + +K  D+ K I    E  H     H+ + +A+++E +   +  
Sbjct: 1312 RLNEKFQ--ESQEEIKSLTKERDNLKTIKEALEVKHDQLKEHIRETLAKIQESQSKQEQS 1369

Query: 585  LVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDL---VQELHILQQKYDEVE 641
            L    + +  +++  K + EME   + +  A+  +E +   L   +QE H   +   + +
Sbjct: 1370 L----NMKEKDNETTKIVSEMEQF-KPKDSALLRIEIEMLGLSKRLQESHDEMKSVAKEK 1424

Query: 642  D---KLADISQLQSDQVCSEIKSV---HLE--EQIDALSASKKELALVIENLKLDKEQLY 693
            D   +L ++ Q +SDQ+   IK +   HLE  E++       KE    I  L+++  +  
Sbjct: 1425 DDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQEETINELRVNLSEKE 1484

Query: 694  GTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGI 753
              I  ++   E I +KLQN IQE   + +K E+ + ++ISE+  K+N  +Q K   +   
Sbjct: 1485 TEISTIQKQLEAINDKLQNKIQE---IYEKEEQFNIKQISEVQEKVNELKQFKEHRK--- 1538

Query: 754  DAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAY 813
                  +D  +++IES++ +  +R+   +E I +M   +  ++R  + L    Q ++   
Sbjct: 1539 -----AKDSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEAL----QIERDQL 1589

Query: 814  SEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQI--LLEENQNLQISLSD 871
             E T    E+V +    M   +  E Q L++   N+  +K  +I  L E+ +  +++L +
Sbjct: 1590 KENT---KEIVAK----MKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQKLNLEN 1642

Query: 872  MQQHYNALVEKANRTDLAESES-TKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEI 930
            ++   N  + +    +L E  S TK +  LR +E  LK          V++ +  E+L  
Sbjct: 1643 IETE-NIRLTQILHENLEEMRSVTKERDDLRSVEETLK----------VERDQLKENLRE 1691

Query: 931  EFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELID 990
                 +E    + K+++   +++ E + +L   + E  N I N+  ++E  N   L+  D
Sbjct: 1692 TITRDLEKQ-EELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDA-LKAQD 1749

Query: 991  KHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKL 1050
              +Q++   +  + ++    I+KL  ++ +K +       K++N Q        D E+  
Sbjct: 1750 LKIQEELRIAHMHLKEQQETIDKLRGIVSEKTD-------KLSNMQ-------KDLENSN 1795

Query: 1051 AQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTE 1110
            A    KL+   +E++    QL+  K+   E Q  V E +   K++K+  LT  ++  + E
Sbjct: 1796 A----KLQEKIQELKANEHQLITLKKDVNETQKKVSEMEQLKKQIKDQSLT--LSKLEIE 1849

Query: 1111 GMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEE--EFIQE---RSVLQEQSAK-- 1163
             + ++  +    ++  +V             LK++ ++  E +QE   R +  +Q  K  
Sbjct: 1850 NLNLAQKLHENLEEMKSVMKERDNLRRVEETLKLERDQLKESLQETKARDLEIQQELKTA 1909

Query: 1164 --LNTELQECYTKI--------IQLETLNTEL-TGHDVVNQE---QINQLKSKLEQLNTE 1209
              L+ E +E   K+        IQ+  +  +L    D + ++   Q +Q+K +   L+  
Sbjct: 1910 RMLSKEHKETVDKLREKISEKTIQISDIQKDLDKSKDELQKKQDRQNHQVKPEKRLLSDG 1969

Query: 1210 NDNLLSTVAELRSSISSAVDQRGFEIAELWK--QHLA---QREADFQKTEHELRVQ---- 1260
              +L  ++ E  S I   + +R  E+ + ++    L+   ++E +FQK E  +RV+    
Sbjct: 1970 QQHLTESLREKCSRIKELL-KRYSEMDDHYECLNRLSLDLEKEIEFQK-ELSMRVKANLS 2027

Query: 1261 LSAFESKY-EQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKE-EHLRNLQEKYADVIN 1318
            L   ++K+ E+L  + Q  + E    +  ++ V S   K+++++ E +   +  + D + 
Sbjct: 2028 LPYLQTKHIEKLFTANQRCSMEFHRIMKKLKYVLSYVTKIKEEQHESINKFEMDFIDEVE 2087

Query: 1319 QIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLK 1378
            + + L  +I+  +                   DL  E +  K   E    +I  E  Q+ 
Sbjct: 2088 KQKELLIKIQHLQQDCDVPSRELRDLKLNQNMDLHIE-EILKDFSESEFPSIKTEFQQVL 2146

Query: 1379 KSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVR 1438
             +                D E    +L + ++ ++  I Q  + +       N+    + 
Sbjct: 2147 SNRKEMTQFLEEWLNTRFDIE----KLKNGIQKENDRICQVNNFF-------NNRIIAIM 2195

Query: 1439 QQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKE-SEIERVK--LIEELNVKI 1495
             +  E+E+R   ++ E E +L  L+ K  +   +Y+T++   +   +V     +  N  +
Sbjct: 2196 NESTEFEERSATISKEWEQDLKSLKEKNEKLFKNYQTLKTSLASGAQVNPTTQDNKNPHV 2255

Query: 1496 TESVS--LNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSK 1553
            T   +    +++ EL  +L E        ++ +   + E+   ND I  LQ  V  S+  
Sbjct: 2256 TSRATQLTTEKIRELENSLHEAKESAMHKESKIIKMQKELEVTNDIIAKLQAKVHESNKC 2315

Query: 1554 IQK 1556
            ++K
Sbjct: 2316 LEK 2318



 Score =  128 bits (308), Expect = 2e-27
 Identities = 257/1487 (17%), Positives = 615/1487 (41%), Gaps = 112/1487 (7%)

Query: 93   SLANTLKQKEILMEKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIK 152
            S    L++KE  ++K+++Y +  K  +  +                  L D   ++   K
Sbjct: 559  SKVELLREKEDQIKKLQEYIDSQKLENIKMDLSYSLESIEDPKQMKQTLFDAETVALDAK 618

Query: 153  EKDNALSV----LQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXX 208
             +   L      L+ KMK + TT   ++  I      +EAK K                 
Sbjct: 619  RESAFLRSENLELKEKMKELATTYKQMENDIQLYQSQLEAKKKMQVDLEKELQSAFNEIT 678

Query: 209  XXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEIS 268
                    ++ K     + +E +  D ++ L K++E  +    +L E   LL   +  + 
Sbjct: 679  KLTSLIDGKVPKDLLCNLELEGKITDLQKELNKEVEENE----ALREEVILLSELK-SLP 733

Query: 269  LEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLE------IANMT 322
             E  +L +E++               L  + +      +  +EE G  +       +N  
Sbjct: 734  SEVERLRKEIQDKSEELHIITSEKDKLFSEVVHKESRVQGLLEEIGKTKDDLATTQSNYK 793

Query: 323  ELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKK-GSPLISRKSGRNTASK 381
               ++ +  + L+    Q  K +  +   M  E   +S  ++K  S L + K+  +  ++
Sbjct: 794  STDQEFQNFKTLHMDFEQKYKMVLEENERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQ 853

Query: 382  MKSPWSQLSSETLNQ-DTDKKINKNEIAKLE-------MVIQSLNKDLVDKEYVISEKDT 433
                 ++   E LN+ +  K+  +N  + L+       ++ + L + L + + +  EKD 
Sbjct: 854  ELQEKTREVQERLNEMEQLKEQLENRDSTLQTVEREKTLITEKLQQTLEEVKTLTQEKDD 913

Query: 434  XXXXXXXXXXGKDTL------IAQLQLEHQQHMEGPSLIHVGTNTEDVNEI-AKVQEQLK 486
                       +D L         + ++ Q+ +   +L  +  + E +N + +K+ E++ 
Sbjct: 914  LKQLQESLQIERDQLKSDIHDTVNMNIDTQEQLRN-ALESLKQHQETINTLKSKISEEVS 972

Query: 487  QELNDEIKDVNVKDL-------IEKLKSAEEQITQL-------NDEIDAANKNMIKVKSN 532
            + L+ E      KD        I+K +  E + TQ        N+ I+   K    ++  
Sbjct: 973  RNLHMEENTGETKDEFQQKMVGIDKKQDLEAKNTQTLTADVKDNEIIEQQRKIFSLIQEK 1032

Query: 533  HKLKLKQMQKTIDNFSKVSDSNKEIVRLT----EELHHLSQKVAELEEEKGNLQLHLVDY 588
            ++L+ + ++  I    ++    KE + +T    EEL  L  ++ + +E     + H +  
Sbjct: 1033 NELQ-QMLESVIAEKEQLKTDLKENIEMTIENQEELRLLGDELKKQQEIVAQEKNHAIKK 1091

Query: 589  DSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVE------- 641
            + G +  S    ++ E+E   + + + +   + Q  ++ +E+  +Q+K +E+E       
Sbjct: 1092 E-GEL--SRTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEIENLKNELK 1148

Query: 642  DKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLE- 700
            +K   +  ++++++    K     E++ +++  +K L  + ++ + +++ L G I+++E 
Sbjct: 1149 NKELTLEHMETERLELAQKLNENYEEVKSITKERKVLKELQKSFETERDHLRGYIREIEA 1208

Query: 701  ---NDKEDIMNKLQN-YIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAK 756
                 KE++  K+ + +++E+ +  D+L +  +EK +++   IN ++  K  T      K
Sbjct: 1209 TGLQTKEEL--KIAHIHLKEHQETIDELRRSVSEKTAQI---INTQDLEKSHT------K 1257

Query: 757  IQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEY 816
            +QE ++ + + E EL      +   +E++  +E        K     + ++ ++   +E 
Sbjct: 1258 LQE-EIPVLHEEQELLPNVKEVSETQETMNELELLTEQSTTKDSTTLARIEMERLRLNEK 1316

Query: 817  TIQEDELVNRLAVLMDHDRVVEKQLLEIEHEN-KELQKKNQILLEENQNLQ---ISLSDM 872
              +  E +  L    D+ + + K+ LE++H+  KE  ++    ++E+Q+ Q   +++ + 
Sbjct: 1317 FQESQEEIKSLTKERDNLKTI-KEALEVKHDQLKEHIRETLAKIQESQSKQEQSLNMKEK 1375

Query: 873  QQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEF 932
                  +V +  +    +S   + + ++  L   L+  +H+    + ++K +++ L+   
Sbjct: 1376 DNETTKIVSEMEQFKPKDSALLRIEIEMLGLSKRLQE-SHDEMKSVAKEKDDLQRLQEVL 1434

Query: 933  NTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKH 992
             ++ +    + K +  K+ +  E +      L+E +  I  L +N+ E  +  +  I K 
Sbjct: 1435 QSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQEETINELRVNLSE-KETEISTIQKQ 1493

Query: 993  VQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQ 1052
            ++    +  +  ++   +  + N     + +E +   ++    + +  S +   ESK+ +
Sbjct: 1494 LEAINDKLQNKIQEIYEKEEQFNIKQISEVQEKVNELKQFKEHRKAKDSALQSIESKMLE 1553

Query: 1053 FTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKE-LKETKLTFEMNIPKTEG 1111
             T +L+  +EE+Q + K+  + K+  E LQI    + DQ+KE  KE     + +  K   
Sbjct: 1554 LTNRLQESQEEIQIMIKEKEEMKRVQEALQI----ERDQLKENTKEIVAKMKESQEKEYQ 1609

Query: 1112 MIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQEC 1171
             +  + +    +    ++            L+   E E I+   +L E   ++ +  +E 
Sbjct: 1610 FLKMTAVNETQEKMCEIEHLKEQFETQKLNLE-NIETENIRLTQILHENLEEMRSVTKER 1668

Query: 1172 YTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNL---LSTVAELRSSISSAV 1228
                   ETL  E        +E I +   K E+L   + +L     T+ +LR  +S   
Sbjct: 1669 DDLRSVEETLKVERDQLKENLRETITRDLEKQEELKIVHMHLKEHQETIDKLRGIVSEKT 1728

Query: 1229 DQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVT 1288
            ++      +L   + A +  D  K + ELR+     + + ++ +D ++    E+T+K+  
Sbjct: 1729 NEISNMQKDLEHSNDALKAQDL-KIQEELRIAHMHLKEQ-QETIDKLRGIVSEKTDKLSN 1786

Query: 1289 MEQVTSLQN-KLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXX 1347
            M++     N KLQ+K + L+  + +   +   +   + ++ + +                
Sbjct: 1787 MQKDLENSNAKLQEKIQELKANEHQLITLKKDVNETQKKVSEMEQLKKQIKDQSLTLSKL 1846

Query: 1348 XXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTH 1407
               +L    + ++ ++E    ++ +E   L++               + + +A+ LE+  
Sbjct: 1847 EIENLNLAQKLHENLEEMK--SVMKERDNLRRVEETLKLERDQLKESLQETKARDLEI-- 1902

Query: 1408 QLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMH 1467
            Q ELK + +  K H+ T+         + +R+++ E   +I D+  + +     L+ K  
Sbjct: 1903 QQELKTARMLSKEHKETV---------DKLREKISEKTIQISDIQKDLDKSKDELQ-KKQ 1952

Query: 1468 ENANHYETMQKESEIE-RVKLIEELNVKITESVSLNKQVAELNKALE 1513
            +  NH    +K    + +  L E L  K +    L K+ +E++   E
Sbjct: 1953 DRQNHQVKPEKRLLSDGQQHLTESLREKCSRIKELLKRYSEMDDHYE 1999



 Score =  106 bits (254), Expect = 6e-21
 Identities = 192/973 (19%), Positives = 428/973 (43%), Gaps = 72/973 (7%)

Query: 140  QLGDVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXX 199
            Q+ +V    N +K+           ++ +E+ +L+L  ++ E  + I+   K        
Sbjct: 1519 QISEVQEKVNELKQFKEHRKAKDSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRV 1578

Query: 200  XXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKL 259
                        E+TK+ + KM+E+    E E++  K   + + + K   I  L+E  + 
Sbjct: 1579 QEALQIERDQLKENTKEIVAKMKES---QEKEYQFLKMTAVNETQEKMCEIEHLKEQFET 1635

Query: 260  LEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCE-EKTEIEEKGSLEI 318
             +     I  E+ +L Q L +              L  +S+E + + E+ +++E     I
Sbjct: 1636 QKLNLENIETENIRLTQILHENLEEMRSVTKERDDL--RSVEETLKVERDQLKENLRETI 1693

Query: 319  ANMTELTKKIELL-----EHLNC--QIRQTNKELENKLATMGTESKAVSSPSKKGSPLIS 371
                E  ++++++     EH     ++R    E  N+++ M  + +  S+ + K   L  
Sbjct: 1694 TRDLEKQEELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEH-SNDALKAQDLKI 1752

Query: 372  RKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEK 431
            ++  R     +K    Q + + L     +K +K  ++ ++  +++ N  L +K   +   
Sbjct: 1753 QEELRIAHMHLKE--QQETIDKLRGIVSEKTDK--LSNMQKDLENSNAKLQEKIQELKAN 1808

Query: 432  DTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELND 491
            +                +++++ + ++ ++  SL       E++N   K+ E L +E+  
Sbjct: 1809 EHQLITLKKDVNETQKKVSEME-QLKKQIKDQSLTLSKLEIENLNLAQKLHENL-EEMKS 1866

Query: 492  EIKDV-NVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNF-SK 549
             +K+  N++ + E LK   +Q+ +   E  A +  + +     ++  K+ ++T+D    K
Sbjct: 1867 VMKERDNLRRVEETLKLERDQLKESLQETKARDLEIQQELKTARMLSKEHKETVDKLREK 1926

Query: 550  VSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLA 609
            +S+   +I  + ++L     ++    ++K + Q H V  +  R++ SD  + + E     
Sbjct: 1927 ISEKTIQISDIQKDLDKSKDEL----QKKQDRQNHQVKPEK-RLL-SDGQQHLTESLREK 1980

Query: 610  ETRLKAISLLESQKFDLVQELHILQQKYD-EVEDKLADISQLQSDQVCSEIKSVHLEEQI 668
             +R+K +    S+  D  + L+ L    + E+E +     +++++     +++ H+E+  
Sbjct: 1981 CSRIKELLKRYSEMDDHYECLNRLSLDLEKEIEFQKELSMRVKANLSLPYLQTKHIEKLF 2040

Query: 669  DALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMS 728
             A      E   +++ LK     +   +  ++ ++ + +NK +      MD  D++EK  
Sbjct: 2041 TANQRCSMEFHRIMKKLKY----VLSYVTKIKEEQHESINKFE------MDFIDEVEKQK 2090

Query: 729  AEKISELLAKINHEEQS-KIQTQFGIDAKI-QERDLYIENIESELSKYKSRICRLEESIA 786
                 ELL KI H +Q   + ++   D K+ Q  DL+IE I  + S+ +    + E    
Sbjct: 2091 -----ELLIKIQHLQQDCDVPSRELRDLKLNQNMDLHIEEILKDFSESEFPSIKTEFQ-Q 2144

Query: 787  VMEDRRYSLERKADQLGSYLQ-EK-----QKAYSEYTIQEDELVNRLAVLMDHDRVVEKQ 840
            V+ +R+   +   + L +    EK     QK         +   NR+  +M+     E++
Sbjct: 2145 VLSNRKEMTQFLEEWLNTRFDIEKLKNGIQKENDRICQVNNFFNNRIIAIMNESTEFEER 2204

Query: 841  LLEI----EHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKY 896
               I    E + K L++KN+ L +  Q L+ SL+   Q  N   +  N+     S +T+ 
Sbjct: 2205 SATISKEWEQDLKSLKEKNEKLFKNYQTLKTSLASGAQ-VNPTTQD-NKNPHVTSRATQL 2262

Query: 897  QTQ-LRDLESNL---KRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEK 952
             T+ +R+LE++L   K      ++ I++ +KE+E +  +   ++++ + +     EK ++
Sbjct: 2263 TTEKIRELENSLHEAKESAMHKESKIIKMQKELE-VTNDIIAKLQAKVHESNKCLEKTKE 2321

Query: 953  NIEYVTQLEAQ-LQEYKNNIENLNMNVE--ELNKM-NLELIDKHVQKQQTQSPDYTEQYI 1008
             I+ +    A   + YK  IE+L M +   +L KM N +  +K +   +  + +Y ++ I
Sbjct: 2322 TIQVLQDKVALGAKPYKEEIEDLKMKLVKIDLEKMKNAKEFEKEISATKA-TVEYQKEVI 2380

Query: 1009 NEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVS 1068
              + + N    Q+ ++   +++   + Q S   +     S + Q  TK   ++ E  R+ 
Sbjct: 2381 RLLRE-NLRRSQQAQDTSVISEH-TDPQPSNKPLTCGGGSGIVQ-NTKALILKSEHIRLE 2437

Query: 1069 KQLLDSKQHNEEL 1081
            K++   KQ NE+L
Sbjct: 2438 KEISKLKQQNEQL 2450



 Score = 82.6 bits (195), Expect = 8e-14
 Identities = 166/855 (19%), Positives = 356/855 (41%), Gaps = 81/855 (9%)

Query: 750  QFGIDAKIQERDLYIENIESE---LSKYKSRICRLEESI--AVMEDRRYSLERKADQLGS 804
            QF   AK  +   Y+  + ++   L +Y+  I  L++ +    +E R  ++E+  DQL  
Sbjct: 326  QFASTAKYMKNTPYVNEVSTDEALLKRYRKEIMDLKKQLEEVSLETRAQAMEK--DQLAQ 383

Query: 805  YLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQN 864
             L+EK        +Q +++ N   +L+    +  +Q L+ + + +      +I   +N N
Sbjct: 384  LLEEKDLLQK---VQNEKIENLTRMLVTSSSLTLQQELKAKRKRRVTWCLGKINKMKNSN 440

Query: 865  LQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKE 924
                 S++  +      K +   L E + +       D+ SN      E +     K   
Sbjct: 441  -YADQSNIPTNITTKTHKLSINLLREIDESVCSES--DVFSNTLDTLSEIEWNPATKLLN 497

Query: 925  IEDLEIEFNT---QIESAIRD-KKVLNEKYEKNIEY-----VTQLEAQLQEYKNNIEN-L 974
             E++E E N+     ++ + D +++  EK E  ++      + + EA  ++ K + EN L
Sbjct: 498  QENIESELNSLRADYDNLVLDYEQLRTEKEEMELKLKEKNDLDEFEALERKTKKDQENEL 557

Query: 975  NMNVEELNKM--NLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQK--DEEIIALNQ 1030
            +  VE L +    ++ + +++  Q+ ++      Y  E  +    +KQ   D E +AL+ 
Sbjct: 558  SSKVELLREKEDQIKKLQEYIDSQKLENIKMDLSYSLESIEDPKQMKQTLFDAETVALDA 617

Query: 1031 KINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDD 1090
            K  +A +   ++  + + K+ +  T  + ME ++Q    QL   K+   +L+   +E   
Sbjct: 618  KRESAFLRSENL--ELKEKMKELATTYKQMENDIQLYQSQLEAKKKMQVDLE---KELQS 672

Query: 1091 QIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEF 1150
               E+  TKLT        +G +    +  +  +    D              ++EE   
Sbjct: 673  AFNEI--TKLT-----SLIDGKVPKDLLCNLELEGKITDLQKELNKEVEENEALREEVIL 725

Query: 1151 IQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQ-----INQLKSKLEQ 1205
            + E   L  +  +L  E+Q+  ++ + + T   +    +VV++E      + ++    + 
Sbjct: 726  LSELKSLPSEVERLRKEIQD-KSEELHIITSEKDKLFSEVVHKESRVQGLLEEIGKTKDD 784

Query: 1206 LNTENDNLLSTVAELRSSISSAVD-QRGFEIAELWKQHLAQREADFQKTEHELRVQLSAF 1264
            L T   N  ST  E ++  +  +D ++ +++     + + Q   +  K   +    L A 
Sbjct: 785  LATTQSNYKSTDQEFQNFKTLHMDFEQKYKMVLEENERMNQEIVNLSKEAQKFDSSLGAL 844

Query: 1265 ESKYEQLLDSVQSSTQEETNKIVTMEQV-TSLQNK---LQDKEEHLRNLQEKYADVINQI 1320
            +++       +Q  T+E   ++  MEQ+   L+N+   LQ  E     + EK    + ++
Sbjct: 845  KTELSYKTQELQEKTREVQERLNEMEQLKEQLENRDSTLQTVEREKTLITEKLQQTLEEV 904

Query: 1321 EILRSEIED----------EKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQ-SIL- 1368
            + L  E +D          E+                    LR   +S KQ QE  + L 
Sbjct: 905  KTLTQEKDDLKQLQESLQIERDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQETINTLK 964

Query: 1369 -NINEE---NAQLKKSSXXXXXXXXXXXXRVN---DAEAKVLELTHQLELKDSEIYQKTH 1421
              I+EE   N  +++++             ++   D EAK  + T   ++KD+EI ++  
Sbjct: 965  SKISEEVSRNLHMEENTGETKDEFQQKMVGIDKKQDLEAKNTQ-TLTADVKDNEIIEQQR 1023

Query: 1422 EYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESE 1481
            +    + ++N+  + +   + E E+   DL  ++  E+ I      EN      +  E +
Sbjct: 1024 KIFSLIQEKNELQQMLESVIAEKEQLKTDL--KENIEMTI------ENQEELRLLGDELK 1075

Query: 1482 IERVKLIEELNVKITESVSLNK---QVAELNKALEEEVAKTNEMQTALENQEIEIVTLND 1538
             ++  + +E N  I +   L++   ++AE+ + L+E+  +  E Q  L N + E+  +  
Sbjct: 1076 KQQEIVAQEKNHAIKKEGELSRTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQK 1135

Query: 1539 EITNLQNMVRASSSK 1553
            +I  ++N+     +K
Sbjct: 1136 KINEIENLKNELKNK 1150



 Score = 72.1 bits (169), Expect = 1e-10
 Identities = 204/1035 (19%), Positives = 425/1035 (41%), Gaps = 122/1035 (11%)

Query: 168  METTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIA 227
            +E   L L EK  E  + I++  K                    E  ++ + K+QE+   
Sbjct: 1306 IEMERLRLNEKFQESQEEIKSLTKERDNLKTIKEALEVKHDQLKEHIRETLAKIQES--- 1362

Query: 228  MEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXX 287
               + K E+   +K+ +++  +I S  E  K  ++A   I +E   L++ L++       
Sbjct: 1363 ---QSKQEQSLNMKEKDNETTKIVSEMEQFKPKDSALLRIEIEMLGLSKRLQESHDEMKS 1419

Query: 288  XXXXXXXLAK-----QSIEPSCEEKTE------IEEKGSLEIANM-------------TE 323
                   L +     QS     +E  +      +E +  L++A+                
Sbjct: 1420 VAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQEETINELRVN 1479

Query: 324  LTKKIELLEHLNCQIRQTNKELENKLATMGTES-----KAVSSPSKKGSPLISRKSGRNT 378
            L++K   +  +  Q+   N +L+NK+  +  +      K +S   +K + L   K  R  
Sbjct: 1480 LSEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQFNIKQISEVQEKVNELKQFKEHRKA 1539

Query: 379  A-SKMKSPWSQLSSETLN-QDTDKKIN-----KNEIAKLEMVIQSLNKDLVD--KEYVIS 429
              S ++S  S++   T   Q++ ++I      K E+ +++  +Q     L +  KE V  
Sbjct: 1540 KDSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQIERDQLKENTKEIVAK 1599

Query: 430  EKDTXXXXXXXX--XXGKDTLIAQLQLEH-QQHMEGPSLIHVGTNTEDVNEIAKVQEQLK 486
             K++              +T     ++EH ++  E   L      TE++     + E L+
Sbjct: 1600 MKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQKLNLENIETENIRLTQILHENLE 1659

Query: 487  QELNDEIKDVNVKDLIEKLKSAEEQITQ-LNDEIDAANKNMIKVKSNHKLKLKQMQKTID 545
            +  +   +  +++ + E LK   +Q+ + L + I    +   ++K  H + LK+ Q+TID
Sbjct: 1660 EMRSVTKERDDLRSVEETLKVERDQLKENLRETITRDLEKQEELKIVH-MHLKEHQETID 1718

Query: 546  NFSK-VSDSNKEIVRLTEELHH----LSQKVAELEEEKGNLQLHLVDY----DSGRMIES 596
                 VS+   EI  + ++L H    L  +  +++EE     +HL +     D  R I S
Sbjct: 1719 KLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQQETIDKLRGIVS 1778

Query: 597  DVYKKMIEME-NLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQS--- 652
            +   K+  M+ +L  +  K    ++  K +   +L  L++  +E + K++++ QL+    
Sbjct: 1779 EKTDKLSNMQKDLENSNAKLQEKIQELKAN-EHQLITLKKDVNETQKKVSEMEQLKKQIK 1837

Query: 653  DQVCS----EIKSVHL----EEQIDALSASKKE---LALVIENLKLDKEQLYGTIKDLEN 701
            DQ  +    EI++++L     E ++ + +  KE   L  V E LKL+++QL  ++++ + 
Sbjct: 1838 DQSLTLSKLEIENLNLAQKLHENLEEMKSVMKERDNLRRVEETLKLERDQLKESLQETKA 1897

Query: 702  DKEDIMNKLQN---YIQENMDLTDKLEKMSAEK---ISELLAKINH--EEQSKIQTQFGI 753
               +I  +L+      +E+ +  DKL +  +EK   IS++   ++   +E  K Q +   
Sbjct: 1898 RDLEIQQELKTARMLSKEHKETVDKLREKISEKTIQISDIQKDLDKSKDELQKKQDRQNH 1957

Query: 754  DAKIQERDLYI--ENIESELSKYKSRICRLEESIAVMEDR-----RYSLE-RKADQLGSY 805
              K ++R L    +++   L +  SRI  L +  + M+D      R SL+  K  +    
Sbjct: 1958 QVKPEKRLLSDGQQHLTESLREKCSRIKELLKRYSEMDDHYECLNRLSLDLEKEIEFQKE 2017

Query: 806  LQEKQKAYSEYTIQEDELVNRLAVL-----MDHDRVVEKQLLEIEHENKELQKKNQIL-- 858
            L  + KA       + + + +L        M+  R+++K    + +  K  +++++ +  
Sbjct: 2018 LSMRVKANLSLPYLQTKHIEKLFTANQRCSMEFHRIMKKLKYVLSYVTKIKEEQHESINK 2077

Query: 859  --------LEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDL-ESNLKR 909
                    +E+ + L I +  +QQ  +    +     L ++     +  L+D  ES    
Sbjct: 2078 FEMDFIDEVEKQKELLIKIQHLQQDCDVPSRELRDLKLNQNMDLHIEEILKDFSESEFPS 2137

Query: 910  ITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKN 969
            I  E Q ++  +K+  + LE   NT+ +          EK +  I+       Q+  + N
Sbjct: 2138 IKTEFQQVLSNRKEMTQFLEEWLNTRFDI---------EKLKNGIQKENDRICQVNNFFN 2188

Query: 970  NIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALN 1029
            N     MN     +     I K  ++      +  E+       L   L     ++    
Sbjct: 2189 NRIIAIMNESTEFEERSATISKEWEQDLKSLKEKNEKLFKNYQTLKTSLAS-GAQVNPTT 2247

Query: 1030 QKINNAQVSYMSM------VSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQI 1083
            Q   N  V+  +       + + E+ L +      + E ++ ++ K+L  +     +LQ 
Sbjct: 2248 QDNKNPHVTSRATQLTTEKIRELENSLHEAKESAMHKESKIIKMQKELEVTNDIIAKLQA 2307

Query: 1084 LVREQDDQIKELKET 1098
             V E +  +++ KET
Sbjct: 2308 KVHESNKCLEKTKET 2322



 Score = 55.2 bits (127), Expect = 1e-05
 Identities = 148/709 (20%), Positives = 296/709 (41%), Gaps = 71/709 (10%)

Query: 320  NMTELTKKIELLEHLNCQIRQTNKELEN-KLATMGTESKAVSSPSKKGSPLISRKSGRNT 378
            ++ E  KK+  +E L  QI+  +  L   ++  +    K   +  +  S +  R + R  
Sbjct: 1818 DVNETQKKVSEMEQLKKQIKDQSLTLSKLEIENLNLAQKLHENLEEMKSVMKERDNLRRV 1877

Query: 379  ASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDK-EYVISEKDTXXXX 437
               +K    QL  E+L +   + +   +  K   ++   +K+ VDK    ISEK T    
Sbjct: 1878 EETLKLERDQLK-ESLQETKARDLEIQQELKTARMLSKEHKETVDKLREKISEK-TIQIS 1935

Query: 438  XXXXXXGKDTLIAQLQLEHQQHMEGPS--LIHVGTN--TEDVNE-IAKVQEQLKQ--ELN 490
                   K     Q + + Q H   P   L+  G    TE + E  ++++E LK+  E++
Sbjct: 1936 DIQKDLDKSKDELQKKQDRQNHQVKPEKRLLSDGQQHLTESLREKCSRIKELLKRYSEMD 1995

Query: 491  DEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKV 550
            D  + +N   L             L  EI+   +  ++VK+N  L   Q +     F+  
Sbjct: 1996 DHYECLNRLSL------------DLEKEIEFQKELSMRVKANLSLPYLQTKHIEKLFTAN 2043

Query: 551  SDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAE 610
               + E  R+ ++L ++   V +++EE+ +  ++  + D    +E    + +I++++L +
Sbjct: 2044 QRCSMEFHRIMKKLKYVLSYVTKIKEEQ-HESINKFEMDFIDEVEKQ-KELLIKIQHLQQ 2101

Query: 611  TRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDA 670
                    L   K +   +LHI        E+ L D S+       SE  S+  E Q   
Sbjct: 2102 DCDVPSRELRDLKLNQNMDLHI--------EEILKDFSE-------SEFPSIKTEFQ--Q 2144

Query: 671  LSASKKELALVIE---NLKLDKEQLYGTIKDLENDKE-DIMNKLQNYIQENMDLTDKLEK 726
            + +++KE+   +E   N + D E+L   I+  END+   + N   N I   M+ + + E+
Sbjct: 2145 VLSNRKEMTQFLEEWLNTRFDIEKLKNGIQK-ENDRICQVNNFFNNRIIAIMNESTEFEE 2203

Query: 727  MSA------EKISELLAKINHEEQSKIQT-QFGIDAKIQERDLYIENIESELSKYKSRIC 779
             SA      E+  + L + N +     QT +  + +  Q      +N    ++   +++ 
Sbjct: 2204 RSATISKEWEQDLKSLKEKNEKLFKNYQTLKTSLASGAQVNPTTQDNKNPHVTSRATQL- 2262

Query: 780  RLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEK 839
               E I  +E+  +  +  A    S + + QK   E  +  D +    A + + ++ +EK
Sbjct: 2263 -TTEKIRELENSLHEAKESAMHKESKIIKMQK---ELEVTNDIIAKLQAKVHESNKCLEK 2318

Query: 840  QLLEIEHENKELQKKNQILLEENQNLQISL--SDMQQHYNALVEKANRTDLAESESTKYQ 897
                I+    ++    +   EE ++L++ L   D+++  NA  ++  +   A   + +YQ
Sbjct: 2319 TKETIQVLQDKVALGAKPYKEEIEDLKMKLVKIDLEKMKNA--KEFEKEISATKATVEYQ 2376

Query: 898  TQ-LRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAI-RDKKVL-----NEKY 950
             + +R L  NL+R      T ++ +  + +           S I ++ K L     + + 
Sbjct: 2377 KEVIRLLRENLRRSQQAQDTSVISEHTDPQPSNKPLTCGGGSGIVQNTKALILKSEHIRL 2436

Query: 951  EKNIEYVTQLEAQLQEYKNNIENLNMNV-EELNKMNLELIDKHVQKQQT 998
            EK I  + Q   QL + KN + + N ++  E+       + +   KQ T
Sbjct: 2437 EKEISKLKQQNEQLIKQKNELLSNNQHLSNEVKTWKERTLKREAHKQVT 2485


>UniRef50_Q231C5 Cluster: Putative uncharacterized protein; n=1;
            Tetrahymena thermophila SB210|Rep: Putative
            uncharacterized protein - Tetrahymena thermophila SB210
          Length = 1759

 Score =  162 bits (394), Expect = 6e-38
 Identities = 274/1426 (19%), Positives = 604/1426 (42%), Gaps = 119/1426 (8%)

Query: 212  EDTKQQMTKMQENFIAMEAEWKDEKQRLL--KDIESKDV-RISSLEEANKLLEAARFEIS 268
            ++ KQ+  K ++ F+    ++ D +++L   K+I  K+V RI +LEE  K       + S
Sbjct: 214  DEIKQKYLKYKQQFMEQRQQFTDLEKKLADEKEINVKNVSRIKTLEEQIKGQLLKLGQES 273

Query: 269  LEHSKLAQELEQXXXXXXXXXXXXXXL-AKQSIEPS--CEEKTEIEEKGSLEIANMTELT 325
             E  +   EL+               L + Q  E +    +  E++EK +  ++ + ++ 
Sbjct: 274  KEKEEAKNELKNVLTKHQNLEQQILILQSNQQNEQTGLSNQLNELQEKYNQIVSYLIQIQ 333

Query: 326  --------KKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRN 377
                    K+++ ++ +   +++ + +    +  +  ++  +++ S++    +       
Sbjct: 334  QTLSCDQGKELDYIQQVMNSLQEQDDQQGQYIIKIQQQTSMINNLSQEKQTYLKENQQLK 393

Query: 378  TASKMKSPWSQLSSETLNQDTDKKINK-----NEIAKL----EMVIQSLNKDLVDKEYVI 428
               +     +Q      NQ+     ++     N+I+++    E  I  L   L  KE  +
Sbjct: 394  LEIQKLEKQNQTIVLNFNQNESSYQSQIQELQNQISQIQNDAEKAITDLQSQLQSKEQEL 453

Query: 429  SEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQE 488
             ++              + +I   + + QQ  +   L+       ++ +  K QEQ   +
Sbjct: 454  EQEKLSIVEFNEKEKELNLIINNYEAQLQQTQQEIQLLKDDLKNRELQQ--KNQEQSIIK 511

Query: 489  LNDEIKDVN--VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDN 546
              DE K +   +  L + + S +      N E++A    + +   +   ++ Q+Q+ +D 
Sbjct: 512  FQDENKALQKQILSLNDVINSNQINQQHNNQELEAQKNQLAQQLEDRNQEISQLQQNLDL 571

Query: 547  FS-KVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIES-DVYKKMIE 604
             + + S  + E+    + L H  Q+  +L+ E  N Q +   +D  ++ +  D+Y++   
Sbjct: 572  LNQEKSQLSVELQEAKQILQHSKQEFEDLQTE-FNSQFNQYQFDIQQLKQQIDIYEQ--N 628

Query: 605  MENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHL 664
             +NL E     I  L ++   L Q+    +QK+ +   + +++  LQ D +  E  + +L
Sbjct: 629  NKNLQE----QIKQLSNENDQLSQDFKNNEQKFIQSSKEFSEL-HLQFDTLQKE--NTNL 681

Query: 665  EEQIDALSASKKELALVIENLKLDKEQLYGTI----KDLENDKEDIMNKLQN----YIQE 716
            + QI   +   K L+L  E     K   Y  +      ++ D + + NK  +    + QE
Sbjct: 682  KNQITQQAEQIKSLSLQGEEGIKQKSVEYAALLLKFNSIDKDHQSLQNKFSDSTNQFEQE 741

Query: 717  ----NMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDA-KI--QERDLYIENIES 769
                N  L DK E+   EK++++ + ++      I+ +  +DA K+  Q     I N   
Sbjct: 742  KKKLNQQLKDKQEQFD-EKVAKITSDLDQTRAEVIKVKQELDASKVANQSSQQIISNQTL 800

Query: 770  ELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAV 829
            +++   S +  L+   A + ++  S   K   L + L  +     E   +      ++  
Sbjct: 801  QINSLTSTVEELKAGGASVSEQAQSYLTKIQTLEASLASQTLKLDEANSKNSAYEQQIQS 860

Query: 830  LMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLA 889
              +  +VV++Q+ ++E E   LQ++ +  L+E QN Q  +  +Q   N   ++  +  L 
Sbjct: 861  QQNQIQVVQEQIKQLEQEKIVLQEQIESHLDEIQNHQEQMKQLQLENNNFEDQVKQLRLE 920

Query: 890  ESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEK 949
                 +   QL   +++L+    + +  +  K+++   L  ++++QI+   +  + L E+
Sbjct: 921  IVNQEENIKQLEFTKNSLEEQIQQLEQQLDNKEEQFNHLNEQYDSQIKGLQQQNEGLLEE 980

Query: 950  YEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYIN 1009
             +   + +   + +++     IE    + E++N  N +LI K  +K Q Q  +  EQ + 
Sbjct: 981  LKNKEQDLILCQNEIKNLNIQIEQEKESCEQINVQNEDLI-KQGEKHQEQISNLEEQ-LK 1038

Query: 1010 EINKLNALLKQKDEEIIALNQKINNAQVSYMSMVS---DYESKLAQFTT-KLENMEEEMQ 1065
             + K NA  +Q+ +   A + + NN   S ++ +    D  ++ AQ    +++N +EE++
Sbjct: 1039 LLQKKNAQYQQQIQVFEASSNEENNELCSKLNQLQQNLDDVNEQAQLQQGQIQNAQEEIE 1098

Query: 1066 RVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDA 1125
              ++Q+   ++ N  ++I   E +  I  L  T  T   N  K + +++    E  +   
Sbjct: 1099 EKNQQIKQLEEFNSNMKIKHDEYEMTISSLNITIQTHLENQRKLDQLLLEKEKEIQTIQE 1158

Query: 1126 NNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTEL 1185
             N+              + Q  ++ ++E+ + Q++  KL   +QE    I +L++ N  L
Sbjct: 1159 ENISLTK----------EQQLIQQSLEEKLMAQKEQEKL--AIQEKQQTIDELQSENESL 1206

Query: 1186 TGHDVVN-QEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLA 1244
              H + N +EQI   +  +EQ + +   +   + +++    + + Q G +  + + Q L 
Sbjct: 1207 Q-HQLNNLEEQIRNNQQLIEQKDQQLYEVSQKLEQIQQE-QAQITQEGAKQNQEYDQKLQ 1264

Query: 1245 QREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEE 1304
              EA  Q+ E EL+ ++   + + + L   ++    ++  K    + +  L+++LQ+  E
Sbjct: 1265 NHEALAQQNE-ELQHEIEIKQDEIQSLQQKIKLLEDDQREK---HQDIEDLKHQLQEMSE 1320

Query: 1305 HLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQE 1364
              +  +++Y + + +   L+ EI                        L  +  SY+Q  +
Sbjct: 1321 QNQGTEQRYTNQMEETLALQMEIRQ-----LHAQIQESHAENNNKDGLIAQLNSYEQDNQ 1375

Query: 1365 QSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYT 1424
                 + E+  +L K+              +N  + ++ +LT QL     +I        
Sbjct: 1376 CLEEKVQEQEVELNKAQ----QTISENQIEINKCKNQIADLTAQLVSLKEQI-------- 1423

Query: 1425 ITLTQRNDEFENVRQQLVEYEKRIEDLTYE-KESELAILRLKMHENANHYETMQ----KE 1479
                Q N   +      + YE++   L  E KE  LA    +  +NA  Y+  Q     E
Sbjct: 1424 ----QENSPSK------IGYEEKYHKLNKEYKEQILAFREQESEQNAKIYQMKQAIETNE 1473

Query: 1480 SEIERVKL-IEELNVKITE-SVSLNKQVAELNKALEEEVAKTNEMQTALENQEI-EIVTL 1536
              I  + + I +L  KIT     L  Q  E  +A+  E    NE + +L+NQE+ E +T 
Sbjct: 1474 ETISNLNIEISDLMYKITGLERELELQTNEF-EAIRAEKEYLNE-KLSLKNQELEESLTQ 1531

Query: 1537 NDEITNLQNMVRASSSKIQKHVSFASDTKQ--GRDEQLDNTMNKEL 1580
            N + ++  +     +++  K   +    +Q   ++++L N +N+ L
Sbjct: 1532 NQQNSHNNDNSHTDNTQSDKIYLYQEQIEQLTHKNQELQNRLNEIL 1577



 Score =  161 bits (391), Expect = 1e-37
 Identities = 234/1149 (20%), Positives = 491/1149 (42%), Gaps = 92/1149 (8%)

Query: 447  TLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLK 506
            TL  Q+ L   + ++  ++      ++ V     +Q ++K +  D I+  N     +  +
Sbjct: 131  TLQIQINLNLIKEVDFTNMSQASNMSKAVAADMFIQNEVKAQ--DHIQQSNQTHAQQVQQ 188

Query: 507  SAEEQITQLNDEIDAANKNMIKVKSNHKLK---LKQMQKTIDNFSKVSDSNKEIVRLTEE 563
                Q     +++     N    +SN ++K   LK  Q+ ++   + +D  K++    E 
Sbjct: 189  QIHHQQNMQQNQM-MVQSNTASQESNDEIKQKYLKYKQQFMEQRQQFTDLEKKLADEKEI 247

Query: 564  LHHLSQKVAELEEE-KGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQ 622
                  ++  LEE+ KG L     +       ++++   + + +NL +  L   S  +++
Sbjct: 248  NVKNVSRIKTLEEQIKGQLLKLGQESKEKEEAKNELKNVLTKHQNLEQQILILQSNQQNE 307

Query: 623  KFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSV-HLEEQIDALSASKKELALV 681
            +  L  +L+ LQ+KY+++   L  I Q  S   C + K + ++++ +++L     +    
Sbjct: 308  QTGLSNQLNELQEKYNQIVSYLIQIQQTLS---CDQGKELDYIQQVMNSLQEQDDQQGQY 364

Query: 682  IENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINH 741
            I  +K+  +Q    I +L  +K       Q Y++EN  L  +++K+  +    ++   N 
Sbjct: 365  I--IKI--QQQTSMINNLSQEK-------QTYLKENQQLKLEIQKLEKQN-QTIVLNFNQ 412

Query: 742  EE---QSKIQTQFGIDAKIQ-ERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLER 797
             E   QS+IQ      ++IQ + +  I +++S+L   +  + + + SI    ++   L  
Sbjct: 413  NESSYQSQIQELQNQISQIQNDAEKAITDLQSQLQSKEQELEQEKLSIVEFNEKEKELNL 472

Query: 798  KADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKK--- 854
              +   + LQ+ Q+   E  + +D+L NR   L   ++  E+ +++ + ENK LQK+   
Sbjct: 473  IINNYEAQLQQTQQ---EIQLLKDDLKNR--ELQQKNQ--EQSIIKFQDENKALQKQILS 525

Query: 855  -NQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHE 913
             N ++     N Q +  +++   N L ++    +   S+  +    L   +S L     E
Sbjct: 526  LNDVINSNQINQQHNNQELEAQKNQLAQQLEDRNQEISQLQQNLDLLNQEKSQLSVELQE 585

Query: 914  HQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEK---YEKN----IEYVTQLEAQ--- 963
             + ++   K+E EDL+ EFN+Q      D + L ++   YE+N     E + QL  +   
Sbjct: 586  AKQILQHSKQEFEDLQTEFNSQFNQYQFDIQQLKQQIDIYEQNNKNLQEQIKQLSNENDQ 645

Query: 964  -LQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNAL----L 1018
              Q++KNN +    + +E ++++L+     +QK+ T   +   Q   +I  L+      +
Sbjct: 646  LSQDFKNNEQKFIQSSKEFSELHLQF--DTLQKENTNLKNQITQQAEQIKSLSLQGEEGI 703

Query: 1019 KQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHN 1078
            KQK  E  AL  K N       S+  D++S   +F+      E+E +++++QL D ++  
Sbjct: 704  KQKSVEYAALLLKFN-------SIDKDHQSLQNKFSDSTNQFEQEKKKLNQQLKDKQEQF 756

Query: 1079 EELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXX 1138
            +E    +    DQ +  +  K+  E++  K         I   +   N++          
Sbjct: 757  DEKVAKITSDLDQTR-AEVIKVKQELDASKVANQSSQQIISNQTLQINSLTSTVEELKAG 815

Query: 1139 XXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQ 1198
               +  ++ + ++ +   L+   A    +L E  +K    E           V QEQI Q
Sbjct: 816  GASVS-EQAQSYLTKIQTLEASLASQTLKLDEANSKNSAYEQQIQSQQNQIQVVQEQIKQ 874

Query: 1199 LKSKLEQLNTENDNLLSTVAELRSSISS-AVDQRGFEIAELWKQHLAQREADFQKTEHEL 1257
            L+ +   L  + ++ L  +   +  +    ++   FE  +  KQ L     + ++   +L
Sbjct: 875  LEQEKIVLQEQIESHLDEIQNHQEQMKQLQLENNNFE--DQVKQ-LRLEIVNQEENIKQL 931

Query: 1258 RVQLSAFESKYEQLLDSVQSSTQEETNKIVTM--EQVTSLQNKLQDKEEHLRNLQEKYAD 1315
                ++ E + +QL   + +  +E+ N +      Q+  LQ + +   E L+N ++    
Sbjct: 932  EFTKNSLEEQIQQLEQQLDNK-EEQFNHLNEQYDSQIKGLQQQNEGLLEELKNKEQDLIL 990

Query: 1316 VINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENA 1375
              N+I+ L  +IE EK                   DL  + + +   QEQ I N+ E+  
Sbjct: 991  CQNEIKNLNIQIEQEK--------ESCEQINVQNEDLIKQGEKH---QEQ-ISNLEEQLK 1038

Query: 1376 QLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFE 1435
             L+K +              N+   ++    +QL+    ++ ++       +    +E E
Sbjct: 1039 LLQKKNAQYQQQIQVFEASSNEENNELCSKLNQLQQNLDDVNEQAQLQQGQIQNAQEEIE 1098

Query: 1436 NVRQQLVEYEK-----RIEDLTYEKESELAILRLKMH-ENANHYETMQKESEIERVKLIE 1489
               QQ+ + E+     +I+   YE       + ++ H EN    + +  E E E ++ I+
Sbjct: 1099 EKNQQIKQLEEFNSNMKIKHDEYEMTISSLNITIQTHLENQRKLDQLLLEKEKE-IQTIQ 1157

Query: 1490 ELNVKITESVSLNKQVAE--LNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMV 1547
            E N+ +T+   L +Q  E  L    E+E     E Q  ++  + E  +L  ++ NL+  +
Sbjct: 1158 EENISLTKEQQLIQQSLEEKLMAQKEQEKLAIQEKQQTIDELQSENESLQHQLNNLEEQI 1217

Query: 1548 RASSSKIQK 1556
            R +   I++
Sbjct: 1218 RNNQQLIEQ 1226



 Score =  153 bits (371), Expect = 4e-35
 Identities = 266/1398 (19%), Positives = 596/1398 (42%), Gaps = 145/1398 (10%)

Query: 216  QQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLA 275
            Q + K+Q+   +M      EKQ  LK+ +   + I  LE+ N+ +     +    +    
Sbjct: 363  QYIIKIQQQ-TSMINNLSQEKQTYLKENQQLKLEIQKLEKQNQTIVLNFNQNESSYQSQI 421

Query: 276  QELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIEL-LEHL 334
            QEL+                A   ++   + K +  E+  L I    E  K++ L + + 
Sbjct: 422  QELQNQISQIQNDAEK----AITDLQSQLQSKEQELEQEKLSIVEFNEKEKELNLIINNY 477

Query: 335  NCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETL 394
              Q++QT +E++  L     +++ +   +++ S +  +   +    ++ S    ++S  +
Sbjct: 478  EAQLQQTQQEIQ--LLKDDLKNRELQQKNQEQSIIKFQDENKALQKQILSLNDVINSNQI 535

Query: 395  NQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQL 454
            NQ  + +       +LE     L + L D+   IS+              K  L  +LQ 
Sbjct: 536  NQQHNNQ-------ELEAQKNQLAQQLEDRNQEISQLQQNLDLLNQE---KSQLSVELQ- 584

Query: 455  EHQQHMEGPSLIHVGTNTEDVNEIAKVQ---EQLKQELNDEIKDVNVKDLIEKLKSAEEQ 511
            E +Q ++          TE  ++  + Q   +QLKQ++  +I + N K+L E++K    Q
Sbjct: 585  EAKQILQHSKQEFEDLQTEFNSQFNQYQFDIQQLKQQI--DIYEQNNKNLQEQIK----Q 638

Query: 512  ITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNK-EIVRLTEELHHLSQK 570
            ++  ND++    KN  +       +  ++    D   K + + K +I +  E++  LS  
Sbjct: 639  LSNENDQLSQDFKNNEQKFIQSSKEFSELHLQFDTLQKENTNLKNQITQQAEQIKSLS-- 696

Query: 571  VAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQEL 630
               L+ E+G ++   V+Y +  +  + + K   + ++L      + +  E +K  L Q+L
Sbjct: 697  ---LQGEEG-IKQKSVEYAALLLKFNSIDK---DHQSLQNKFSDSTNQFEQEKKKLNQQL 749

Query: 631  HILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKE 690
               Q+++DE   K+A I+    DQ  +E+  + +++++DA   + +    +I N  L   
Sbjct: 750  KDKQEQFDE---KVAKITS-DLDQTRAEV--IKVKQELDASKVANQSSQQIISNQTLQIN 803

Query: 691  QLYGTIKDLENDKEDIMNKLQNYI-----------QENMDLTDKLEKMSA---------E 730
             L  T+++L+     +  + Q+Y+            + + L +   K SA          
Sbjct: 804  SLTSTVEELKAGGASVSEQAQSYLTKIQTLEASLASQTLKLDEANSKNSAYEQQIQSQQN 863

Query: 731  KISELLAKINHEEQSKIQTQFGIDAKIQE--------RDLYIE--NIESELSKYKSRICR 780
            +I  +  +I   EQ KI  Q  I++ + E        + L +E  N E ++ + +  I  
Sbjct: 864  QIQVVQEQIKQLEQEKIVLQEQIESHLDEIQNHQEQMKQLQLENNNFEDQVKQLRLEIVN 923

Query: 781  LEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAV----LMDHDRV 836
             EE+I  +E  + SLE +  QL   L  K++ ++    Q D  +  L      L++  + 
Sbjct: 924  QEENIKQLEFTKNSLEEQIQQLEQQLDNKEEQFNHLNEQYDSQIKGLQQQNEGLLEELKN 983

Query: 837  VEKQLLEIEHENKELQKKNQILLEENQNLQISLSDM----QQHYNALVEKANRTDLAESE 892
             E+ L+  ++E K L  + +   E  + + +   D+    ++H   +     +  L + +
Sbjct: 984  KEQDLILCQNEIKNLNIQIEQEKESCEQINVQNEDLIKQGEKHQEQISNLEEQLKLLQKK 1043

Query: 893  STKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNT---QIESAIRDKKVLNEK 949
            + +YQ Q++  E++     +E  + + Q ++ ++D+  +      QI++A  + +  N++
Sbjct: 1044 NAQYQQQIQVFEASSNEENNELCSKLNQLQQNLDDVNEQAQLQQGQIQNAQEEIEEKNQQ 1103

Query: 950  YEKNIEYVTQLEAQLQEYKNNIENLNMNV----EELNKMNLELIDKHVQKQQTQSPDYT- 1004
             ++  E+ + ++ +  EY+  I +LN+ +    E   K++  L++K  + Q  Q  + + 
Sbjct: 1104 IKQLEEFNSNMKIKHDEYEMTISSLNITIQTHLENQRKLDQLLLEKEKEIQTIQEENISL 1163

Query: 1005 --EQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEE 1062
              EQ + + +    L+ QK++E +A+ +K           + + +S+      +L N+EE
Sbjct: 1164 TKEQQLIQQSLEEKLMAQKEQEKLAIQEK--------QQTIDELQSENESLQHQLNNLEE 1215

Query: 1063 EMQRVSKQLLDSKQH-----NEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISST 1117
            ++ R ++QL++ K       +++L+ + +EQ    +E  +    ++  +   E +     
Sbjct: 1216 QI-RNNQQLIEQKDQQLYEVSQKLEQIQQEQAQITQEGAKQNQEYDQKLQNHEAL----- 1269

Query: 1118 IEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQ 1177
             +   +  + ++            +K+ E+++  +E+    +    L  +LQE   +   
Sbjct: 1270 AQQNEELQHEIEIKQDEIQSLQQKIKLLEDDQ--REK---HQDIEDLKHQLQEMSEQNQG 1324

Query: 1178 LETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRS------SISSAVDQR 1231
             E   T      +  Q +I QL +++++ + EN+N    +A+L S       +   V ++
Sbjct: 1325 TEQRYTNQMEETLALQMEIRQLHAQIQESHAENNNKDGLIAQLNSYEQDNQCLEEKVQEQ 1384

Query: 1232 GFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSST--QEETNKIVTM 1289
              E+ +  +Q +++ + +  K ++++    +   S  EQ+ ++  S    +E+ +K+   
Sbjct: 1385 EVELNKA-QQTISENQIEINKCKNQIADLTAQLVSLKEQIQENSPSKIGYEEKYHKLNKE 1443

Query: 1290 EQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXX 1349
             +   L  + Q+ E++ +  Q K A   N+  I    IE   + +               
Sbjct: 1444 YKEQILAFREQESEQNAKIYQMKQAIETNEETISNLNIEISDLMY-------KITGLERE 1496

Query: 1350 XDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQL 1409
             +L+T N+      E+  LN   E   LK                 ND        +H  
Sbjct: 1497 LELQT-NEFEAIRAEKEYLN---EKLSLKNQELEESLTQNQQNSHNNDN-------SHTD 1545

Query: 1410 ELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHEN 1469
              +  +IY    E    LT +N E +N   +++         + ++E+  ++  L    N
Sbjct: 1546 NTQSDKIY-LYQEQIEQLTHKNQELQNRLNEILNQNIMNTPQSKDRENRNSVKSLSSPIN 1604

Query: 1470 ANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELN-KALEEEVAKTNEMQTALEN 1528
               +   Q + E+ +VK   EL+    + V+  + + +   K +++E+ K  +    +E 
Sbjct: 1605 NKTFANNQVDQELSQVKQDFELSKIELQKVTQERDMMKNEFKQMKQEIQKAKDSDKIIET 1664

Query: 1529 QEIEIVTLNDEITNLQNM 1546
               ++V    ++ ++ NM
Sbjct: 1665 LTDQLVKSKQKLGDMYNM 1682



 Score =  125 bits (302), Expect = 9e-27
 Identities = 236/1253 (18%), Positives = 538/1253 (42%), Gaps = 100/1253 (7%)

Query: 94   LANTLKQKEILMEKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKE 153
            L  T ++ ++L + +K  +   K    +I++                L DV + SN I +
Sbjct: 481  LQQTQQEIQLLKDDLKNRELQQKNQEQSIIKFQDENKALQKQILS--LNDVIN-SNQINQ 537

Query: 154  KDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXED 213
            + N    L+ +   +   + D  ++I++  Q ++  N+  +                 + 
Sbjct: 538  QHNNQE-LEAQKNQLAQQLEDRNQEISQLQQNLDLLNQEKSQLSVELQEAKQIL----QH 592

Query: 214  TKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSK 273
            +KQ+   +Q  F +   +++ + Q+L + I+  +    +L+E  K L     ++S +   
Sbjct: 593  SKQEFEDLQTEFNSQFNQYQFDIQQLKQQIDIYEQNNKNLQEQIKQLSNENDQLSQDFKN 652

Query: 274  LAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEH 333
              Q+  Q              L K++     +   + E+  SL +     + +K      
Sbjct: 653  NEQKFIQSSKEFSELHLQFDTLQKENTNLKNQITQQAEQIKSLSLQGEEGIKQKSVEYAA 712

Query: 334  LNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGR--NTASKMKSPWSQLSS 391
            L  +    +K+ ++        +       KK +  +  K  +     +K+ S   Q  +
Sbjct: 713  LLLKFNSIDKDHQSLQNKFSDSTNQFEQEKKKLNQQLKDKQEQFDEKVAKITSDLDQTRA 772

Query: 392  ETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQ 451
            E +      K+ K E+   ++  QS ++ ++  + +     T             +  AQ
Sbjct: 773  EVI------KV-KQELDASKVANQS-SQQIISNQTLQINSLTSTVEELKAGGASVSEQAQ 824

Query: 452  LQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQ 511
              L   Q +E  SL       ++ N      EQ  Q   ++I+ V      E++K  E++
Sbjct: 825  SYLTKIQTLEA-SLASQTLKLDEANSKNSAYEQQIQSQQNQIQVVQ-----EQIKQLEQE 878

Query: 512  ITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKV 571
               L ++I++   ++ +++ NH+ ++KQ+Q   +NF        ++ +L  E+ +  + +
Sbjct: 879  KIVLQEQIES---HLDEIQ-NHQEQMKQLQLENNNF------EDQVKQLRLEIVNQEENI 928

Query: 572  AELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELH 631
             +LE  K +L+  +      + +E  +  K  +  +L E     I  L+ Q   L++EL 
Sbjct: 929  KQLEFTKNSLEEQI------QQLEQQLDNKEEQFNHLNEQYDSQIKGLQQQNEGLLEELK 982

Query: 632  ILQQKYDEVEDKLADIS-QLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKL--- 687
              +Q     ++++ +++ Q++ ++   E  +V  E+ I      +++++ + E LKL   
Sbjct: 983  NKEQDLILCQNEIKNLNIQIEQEKESCEQINVQNEDLIKQGEKHQEQISNLEEQLKLLQK 1042

Query: 688  DKEQLYGTIKDLENDKEDIMNKL---QNYIQENMDLTDKLEKMSAEKISELLAKINHE-E 743
               Q    I+  E    +  N+L    N +Q+N+D  ++  ++   +I     +I  + +
Sbjct: 1043 KNAQYQQQIQVFEASSNEENNELCSKLNQLQQNLDDVNEQAQLQQGQIQNAQEEIEEKNQ 1102

Query: 744  QSKIQTQFGIDAKIQ--ERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQ 801
            Q K   +F  + KI+  E ++ I ++   +  +     +L++ +   E    +++ +   
Sbjct: 1103 QIKQLEEFNSNMKIKHDEYEMTISSLNITIQTHLENQRKLDQLLLEKEKEIQTIQEENIS 1162

Query: 802  LGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEE 861
            L    Q  Q++  E  + + E   +LA+  +  + ++    E++ EN+ LQ +   L E+
Sbjct: 1163 LTKEQQLIQQSLEEKLMAQKE-QEKLAI-QEKQQTID----ELQSENESLQHQLNNLEEQ 1216

Query: 862  NQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQK 921
             +N Q  +    Q    + +K  +    +++ T+ +   ++ E + K   HE    + Q+
Sbjct: 1217 IRNNQQLIEQKDQQLYEVSQKLEQIQQEQAQITQ-EGAKQNQEYDQKLQNHE---ALAQQ 1272

Query: 922  KKEIE-DLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNM---- 976
             +E++ ++EI+   +I+S  +  K+L +   +  + +  L+ QLQE     +        
Sbjct: 1273 NEELQHEIEIK-QDEIQSLQQKIKLLEDDQREKHQDIEDLKHQLQEMSEQNQGTEQRYTN 1331

Query: 977  NVEELNKMNLELIDKHVQKQQTQSPDYTEQ----YINEINKLNALLKQK-DEEIIALNQK 1031
             +EE   + +E+   H Q Q++ + +  +      +N   + N  L++K  E+ + LN+ 
Sbjct: 1332 QMEETLALQMEIRQLHAQIQESHAENNNKDGLIAQLNSYEQDNQCLEEKVQEQEVELNKA 1391

Query: 1032 INNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQ 1091
                  + +  ++  ++++A  T +L +++E++Q  S   +    + E+   L +E  +Q
Sbjct: 1392 QQTISENQIE-INKCKNQIADLTAQLVSLKEQIQENSPSKIG---YEEKYHKLNKEYKEQ 1447

Query: 1092 IKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEE-EF 1150
            I   +E +      I + +   I +  E +S+    +             L++Q  E E 
Sbjct: 1448 ILAFREQESEQNAKIYQMK-QAIETNEETISNLNIEISDLMYKITGLERELELQTNEFEA 1506

Query: 1151 IQ-ERSVLQEQSAKLNTELQECYTKIIQ----LETLNTELTGHDVV--NQEQINQLKSKL 1203
            I+ E+  L E+ +  N EL+E  T+  Q     +  +T+ T  D +   QEQI QL  K 
Sbjct: 1507 IRAEKEYLNEKLSLKNQELEESLTQNQQNSHNNDNSHTDNTQSDKIYLYQEQIEQLTHKN 1566

Query: 1204 EQLNTE-----NDNLLSTV----AELRSSI---SSAVDQRGFEIAELWKQHLAQREADFQ 1251
            ++L        N N+++T      E R+S+   SS ++ + F   ++  Q L+Q + DF+
Sbjct: 1567 QELQNRLNEILNQNIMNTPQSKDRENRNSVKSLSSPINNKTFANNQV-DQELSQVKQDFE 1625

Query: 1252 KTEHELR---VQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQD 1301
             ++ EL+    +    +++++Q+   +Q +   +       +Q+   + KL D
Sbjct: 1626 LSKIELQKVTQERDMMKNEFKQMKQEIQKAKDSDKIIETLTDQLVKSKQKLGD 1678


>UniRef50_Q6FWE0 Cluster: Candida glabrata strain CBS138 chromosome D
            complete sequence; n=1; Candida glabrata|Rep: Candida
            glabrata strain CBS138 chromosome D complete sequence -
            Candida glabrata (Yeast) (Torulopsis glabrata)
          Length = 1980

 Score =  162 bits (394), Expect = 6e-38
 Identities = 266/1241 (21%), Positives = 539/1241 (43%), Gaps = 112/1241 (9%)

Query: 376  RNTASKMKSPWSQL---SSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKD 432
            +N  + +KS  S+L   SSE  +Q  +K+I K+  +  E   + L K+L DK   ISEK 
Sbjct: 703  QNQCTSLKSHLSELEIQSSEKRSQ-LEKQI-KSLTSNFE-ASEQLKKELEDKLSTISEKQ 759

Query: 433  TXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQ-EQLKQELND 491
                        K   +A++   +       SL  + T  E + E  K Q    K++L  
Sbjct: 760  QTLESEYEE---KKKELAEITANNT------SLEQLNTQKEKLTEELKKQLADTKEKLTQ 810

Query: 492  EIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVS 551
              K V  K+L E  +  E+ I ++N ++ +  +   K++ ++K   K ++KT ++F+K  
Sbjct: 811  MEKQV--KELSEHKEKNEQGINKMNRDLFSLQREKQKLEEDNKQSKKDLEKTKNDFTKQE 868

Query: 552  DSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAET 611
               K+ ++  E L      + E  E+         +Y     I+ ++  +M E +   ++
Sbjct: 869  TKLKDQIKAKEIL------IKETTEKLNEATTQSKEYHD--KIQ-NITSEMNEWQAKYKS 919

Query: 612  RLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVC---SEIKSVHLEEQI 668
                ++ L  +   L      LQ + D ++ +L  I+Q +   +    SE KS  LEE  
Sbjct: 920  HDTFVAKLTEKLKALATSFKELQAERDTIKSELEKITQERDTNIAAITSEKKS--LEELY 977

Query: 669  DALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMS 728
              + + K  L   I  L+   E      K  E++K  + ++ +    E  +     EK+ 
Sbjct: 978  KNMESEKDGLLKKITELETGIE---SDNKKFEDEKSALESETKRLTLEIAEFKSNAEKLD 1034

Query: 729  AEKISELLAKINHEEQSKI-QTQFGIDAK---IQERDLYIENIESELSKYKSRICRLEES 784
             E+  E L  +    + K+ +    ID K   +      IE  +SE+S  K+ I +L+ S
Sbjct: 1035 TER--ERLQTLTESYKEKLNEANSSIDEKNKDLNNIQQQIEGSQSEISTLKAEITQLKTS 1092

Query: 785  IAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEI 844
            +   +  R +LE+  ++  +Y+Q  Q    +   + D L +     +D++  ++++  E+
Sbjct: 1093 LNEEKSTRKALEKLKEENETYIQSAQDELLQLQKEVDLLKSENKDALDNNSSLKQKYDEL 1152

Query: 845  EHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLE 904
                KEL+ KN   LE  Q     LSD   + N+ +E+     L     +KY T +++LE
Sbjct: 1153 V---KELELKN---LESKQ-----LSDNSLNLNSKIEQ-----LEGDIKSKYNT-IKELE 1195

Query: 905  SNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNE---KYEKNIEYVTQLE 961
              L     E +  I      I D+E++ N++ E        L E    +EK      +LE
Sbjct: 1196 EKLSTSLQEREENIA----NIADIELKLNSKEEQYTEQTNKLEELRISFEKKQSECKELE 1251

Query: 962  AQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQ- 1020
            ++L+   ++++  N   +EL K NL+ + K  +K +       E    E  K    + Q 
Sbjct: 1252 SKLKSSNDDLQEKNRLTKELQK-NLDSLMKDKEKTEGSLQSLLEDKKQEEKKYKEEIDQL 1310

Query: 1021 --KDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHN 1078
              ++E+I   N+++N     Y + +   + +L      + + +++M ++ +++ D     
Sbjct: 1311 GKENEDITKQNKELNLRLEDYSAKIDAKDEELKLANDAVASTKKKMLKLEEKIKDL---- 1366

Query: 1079 EELQILVREQDDQIK-ELKETKLTFEM------NIPKTEGMIISSTIEPMSDDANNVDXX 1131
            E+ Q + ++ ++ +K EL++T L          NI K +  +  +  + + ++    +  
Sbjct: 1367 EDTQHIFKDSENSLKSELEKTALEMNELRSDNDNIIKLKNELQRTNDKLIEENKRTEEKL 1426

Query: 1132 XXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQ-LETLNTELTGHDV 1190
                      LK  + + F +ER ++ E S+ +  E  E  + + + +ET+ +E      
Sbjct: 1427 RSEVAKLKDELKT-KSDTFEKERKLMNEDSSTIIKEYSEKISSLEEKVETIKSEY----- 1480

Query: 1191 VNQEQINQLKSKLEQLNTENDNLLSTVAELRSSI---SSAVDQRGFEIAELWKQHLAQRE 1247
               ++IN L+ K E L +E  +    + +    I    +   ++  EI ++ K  L   E
Sbjct: 1481 --DKEINILEDKKEVLESELSDKKQEIIDYNQKIKEQETKATEKEKEI-QVAKNALKNAE 1537

Query: 1248 ADFQKTEHELRVQLSAFESKYEQLLDSVQ---SSTQEETNKIVTMEQVTSLQNKLQDKE- 1303
               +  E++LR  ++  E +   L    Q    S  +  N I  +++  S Q +L DK+ 
Sbjct: 1538 KKKKDIENDLRTTIATVEKENTTLKRENQLKSESIDKHQNNIHLLQEELSKQKELADKKH 1597

Query: 1304 EHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQ 1363
            + +R L+++ + +I++I+    ++E +K                   + +T  +  +  Q
Sbjct: 1598 DEIRKLEKENSKMIDRID----KLEKQKADTNEKIANIEKENSSLISERKTLVEKVENFQ 1653

Query: 1364 EQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEY 1423
            ++ I N+     +    S               + +  + EL ++LE ++ ++  K  E+
Sbjct: 1654 DE-ITNLKSSLEKNDSLSSSHDELKDKFNELETELKRNLTEL-NKLESENKQLSDKVIEH 1711

Query: 1424 TITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYE--TMQKESE 1481
               ++    E    ++ L E E  I  L  +  +EL     K      HYE    +K+S+
Sbjct: 1712 EEKVSMVEKELSTAQKTLKEREDVINKLK-DSNNELNKTIDKHGATEKHYEESITKKDSD 1770

Query: 1482 IERV-KLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEI 1540
            I ++ K I+++  K++  +    + A L   LE++       ++ L+ QE+E      + 
Sbjct: 1771 IAQLKKKIKDIEDKLSNILEEKAKAAMLMTQLEKDKTDLKNSESELK-QELE--HYRSKY 1827

Query: 1541 TNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELL 1581
            ++L++ ++ S+ + +KHV   S  +Q +   LD    K+ L
Sbjct: 1828 SSLESKLK-STEEAKKHVEEES-REQHQSMSLDLKATKDKL 1866



 Score =  153 bits (370), Expect = 5e-35
 Identities = 270/1348 (20%), Positives = 584/1348 (43%), Gaps = 142/1348 (10%)

Query: 296  AKQSIEPSCEE-KTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGT 354
            A + ++  C   K+ + E         ++L K+I+ L        Q  KELE+KL+T+  
Sbjct: 698  AFEEVQNQCTSLKSHLSELEIQSSEKRSQLEKQIKSLTSNFEASEQLKKELEDKLSTISE 757

Query: 355  ESKAVSSPSKKGSPLISRKSGRNTA-SKMKSPWSQLSSETLNQ--DTDKKINKNE----- 406
            + + + S  ++    ++  +  NT+  ++ +   +L+ E   Q  DT +K+ + E     
Sbjct: 758  KQQTLESEYEEKKKELAEITANNTSLEQLNTQKEKLTEELKKQLADTKEKLTQMEKQVKE 817

Query: 407  ----IAKLEMVIQSLNKDL--VDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHM 460
                  K E  I  +N+DL  + +E    E+D             D    + +L+ Q  +
Sbjct: 818  LSEHKEKNEQGINKMNRDLFSLQREKQKLEEDNKQSKKDLEKTKNDFTKQETKLKDQ--I 875

Query: 461  EGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEID 520
            +   ++ +   TE +NE     ++   ++ +   ++N  +   K KS +  + +L +++ 
Sbjct: 876  KAKEIL-IKETTEKLNEATTQSKEYHDKIQNITSEMN--EWQAKYKSHDTFVAKLTEKLK 932

Query: 521  AANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGN 580
            A   +  ++++       +++K     ++  D+N  I  +T E   L +    +E EK  
Sbjct: 933  ALATSFKELQAERDTIKSELEK----ITQERDTN--IAAITSEKKSLEELYKNMESEKDG 986

Query: 581  LQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISL------LESQKFDLVQE-LHIL 633
            L   + + ++G  IESD  KK  + ++  E+  K ++L        ++K D  +E L  L
Sbjct: 987  LLKKITELETG--IESD-NKKFEDEKSALESETKRLTLEIAEFKSNAEKLDTERERLQTL 1043

Query: 634  QQKYDE--------VEDKLADISQLQSDQVCSEIKSVHLEEQIDALSAS---KKELALVI 682
             + Y E        +++K  D++ +Q     S+ +   L+ +I  L  S   +K     +
Sbjct: 1044 TESYKEKLNEANSSIDEKNKDLNNIQQQIEGSQSEISTLKAEITQLKTSLNEEKSTRKAL 1103

Query: 683  ENLKLDKEQLYGTIKD--LENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKIN 740
            E LK + E    + +D  L+  KE  + K +N  ++ +D    L++   E + EL  K N
Sbjct: 1104 EKLKEENETYIQSAQDELLQLQKEVDLLKSEN--KDALDNNSSLKQKYDELVKELELK-N 1160

Query: 741  HEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAV-MEDRRYSLERKA 799
             E +        +++K       IE +E ++    + I  LEE ++  +++R  ++   A
Sbjct: 1161 LESKQLSDNSLNLNSK-------IEQLEGDIKSKYNTIKELEEKLSTSLQEREENIANIA 1213

Query: 800  DQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILL 859
            D +   L  K++ Y+E T + +EL  R++         E +  +++  N +LQ+KN++  
Sbjct: 1214 D-IELKLNSKEEQYTEQTNKLEEL--RISFEKKQSECKELE-SKLKSSNDDLQEKNRLTK 1269

Query: 860  EENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIV 919
            E  +NL   + D ++   +L    +  +  + E  KY+ ++  L    + IT +++ L +
Sbjct: 1270 ELQKNLDSLMKDKEKTEGSL---QSLLEDKKQEEKKYKEEIDQLGKENEDITKQNKELNL 1326

Query: 920  Q-----KKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQL-EAQLQEYKNNIEN 973
            +      K + +D E++      ++ + K +  E+  K++E    + +      K+ +E 
Sbjct: 1327 RLEDYSAKIDAKDEELKLANDAVASTKKKMLKLEEKIKDLEDTQHIFKDSENSLKSELEK 1386

Query: 974  LNMNVEELNKMNLELIDKHVQKQQT-----QSPDYTEQYI-NEINKLNALLKQKDEEIIA 1027
              + + EL   N  +I    + Q+T     +    TE+ + +E+ KL   LK K  +   
Sbjct: 1387 TALEMNELRSDNDNIIKLKNELQRTNDKLIEENKRTEEKLRSEVAKLKDELKTK-SDTFE 1445

Query: 1028 LNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRV------SKQLLDSKQHNEEL 1081
              +K+ N   S  +++ +Y  K++    K+E ++ E  +        K++L+S+  +++ 
Sbjct: 1446 KERKLMNEDSS--TIIKEYSEKISSLEEKVETIKSEYDKEINILEDKKEVLESELSDKKQ 1503

Query: 1082 QILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXX 1141
            +I+   Q  + +E K T+   E+ + K     + +  +   D  N++             
Sbjct: 1504 EIIDYNQKIKEQETKATEKEKEIQVAKN---ALKNAEKKKKDIENDLRTTIATVEKENTT 1560

Query: 1142 LKVQEE--EEFIQERS----VLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQ 1195
            LK + +   E I +      +LQE+ +K      + + +I +LE  N+++       ++Q
Sbjct: 1561 LKRENQLKSESIDKHQNNIHLLQEELSKQKELADKKHDEIRKLEKENSKMIDRIDKLEKQ 1620

Query: 1196 INQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEH 1255
                  K+  +  EN +L+S     R ++   V+    EI  L K  L + ++    +  
Sbjct: 1621 KADTNEKIANIEKENSSLISE----RKTLVEKVENFQDEITNL-KSSLEKNDS-LSSSHD 1674

Query: 1256 ELRVQLSAFESKYEQ---LLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEK 1312
            EL+ + +  E++ ++    L+ ++S  ++ ++K++  E+  S+  K  +     + L+E+
Sbjct: 1675 ELKDKFNELETELKRNLTELNKLESENKQLSDKVIEHEEKVSMVEK--ELSTAQKTLKER 1732

Query: 1313 YADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINE 1372
              DVIN+++   +E+                       D   ++ + ++  E+SI   + 
Sbjct: 1733 -EDVINKLKDSNNELN-------------------KTID---KHGATEKHYEESITKKDS 1769

Query: 1373 ENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRND 1432
            + AQLKK               + + +AK   L  QLE   +++     E    L     
Sbjct: 1770 DIAQLKKK----IKDIEDKLSNILEEKAKAAMLMTQLEKDKTDLKNSESELKQELEHYRS 1825

Query: 1433 EFENVRQQL---VEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEI--ERVKL 1487
            ++ ++  +L    E +K +E+ + E+   +++      +     E    E +   ++V+L
Sbjct: 1826 KYSSLESKLKSTEEAKKHVEEESREQHQSMSLDLKATKDKLKSAEISISEMDAIKKQVEL 1885

Query: 1488 IEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMV 1547
            + + NV +    +     A+L   L +E+ K NE      N   E+  L   +T L    
Sbjct: 1886 LTKENVDLKSKSNKADNSAKLKSEL-DELKKENEKLQLKVNDRSELDDLMLLVTELDEKN 1944

Query: 1548 RASSSKIQK-HVSFASDTKQGRDEQLDN 1574
                 K+ +  V  +SD +   D+  D+
Sbjct: 1945 SKYREKLSELGVELSSDEEDDDDDDDDD 1972



 Score =  126 bits (305), Expect = 4e-27
 Identities = 209/1135 (18%), Positives = 479/1135 (42%), Gaps = 82/1135 (7%)

Query: 99   KQKEILMEKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNAL 158
            KQ+  L ++IK  KE+  + +T  +                   ++       K  D  +
Sbjct: 866  KQETKLKDQIKA-KEILIKETTEKLNEATTQSKEYHDKIQNITSEMNEWQAKYKSHDTFV 924

Query: 159  SVLQVKMKIMETTILDLQEKIN----EKDQIIEAKNK---ATTXXXXXXXXXXXXXXXXX 211
            + L  K+K + T+  +LQ + +    E ++I + ++    A T                 
Sbjct: 925  AKLTEKLKALATSFKELQAERDTIKSELEKITQERDTNIAAITSEKKSLEELYKNMESEK 984

Query: 212  EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271
            +   +++T+++    +   +++DEK  L  + +   + I+  +   + L+  R  +    
Sbjct: 985  DGLLKKITELETGIESDNKKFEDEKSALESETKRLTLEIAEFKSNAEKLDTERERLQTLT 1044

Query: 272  SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEE----KTEIEE-KGSLEIANMTELTK 326
                ++L +              + +Q IE S  E    K EI + K SL     T   K
Sbjct: 1045 ESYKEKLNEANSSIDEKNKDLNNI-QQQIEGSQSEISTLKAEITQLKTSLNEEKSTR--K 1101

Query: 327  KIELLEHLNCQIRQTNKE----LENKLATMGTESKAV----SSPSKKGSPLISRKSGRNT 378
             +E L+  N    Q+ ++    L+ ++  + +E+K      SS  +K   L+     +N 
Sbjct: 1102 ALEKLKEENETYIQSAQDELLQLQKEVDLLKSENKDALDNNSSLKQKYDELVKELELKNL 1161

Query: 379  ASKMKSPWS-QLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXX 437
             SK  S  S  L+S+    + D K   N I +LE  + +  ++  +    I++ +     
Sbjct: 1162 ESKQLSDNSLNLNSKIEQLEGDIKSKYNTIKELEEKLSTSLQEREENIANIADIELKLNS 1221

Query: 438  XXXXXXGKDTLIAQLQLEHQQHMEGPSLIH--VGTNTEDVNEIAKVQEQLKQELNDEIKD 495
                   +   + +L++  ++       +   + ++ +D+ E  ++ ++L++ L+  +KD
Sbjct: 1222 KEEQYTEQTNKLEELRISFEKKQSECKELESKLKSSNDDLQEKNRLTKELQKNLDSLMKD 1281

Query: 496  V-----NVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTID-NFSK 549
                  +++ L+E  K  E++  +  D++   N+++ K      L+L+     ID    +
Sbjct: 1282 KEKTEGSLQSLLEDKKQEEKKYKEEIDQLGKENEDITKQNKELNLRLEDYSAKIDAKDEE 1341

Query: 550  VSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLA 609
            +  +N  +    +++  L +K+ +LE+ +     H+   DS   ++S++ K  +EM  L 
Sbjct: 1342 LKLANDAVASTKKKMLKLEEKIKDLEDTQ-----HIFK-DSENSLKSELEKTALEMNELR 1395

Query: 610  ETRLKAISL---LESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEE 666
                  I L   L+     L++E    ++K      KL D  + +SD    E K ++ E+
Sbjct: 1396 SDNDNIIKLKNELQRTNDKLIEENKRTEEKLRSEVAKLKDELKTKSDTFEKERKLMN-ED 1454

Query: 667  QIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKL-- 724
                +    ++++ + E ++  K +    I  LE+ KE + ++L +  QE +D   K+  
Sbjct: 1455 SSTIIKEYSEKISSLEEKVETIKSEYDKEINILEDKKEVLESELSDKKQEIIDYNQKIKE 1514

Query: 725  -EKMSAEKISEL-LAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLE 782
             E  + EK  E+ +AK   +   K +     D +       I  +E E +  K       
Sbjct: 1515 QETKATEKEKEIQVAKNALKNAEKKKKDIENDLRTT-----IATVEKENTTLKRENQLKS 1569

Query: 783  ESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLL 842
            ESI   ++  + L+ +  +      +K     +   +  ++++R+  L        +++ 
Sbjct: 1570 ESIDKHQNNIHLLQEELSKQKELADKKHDEIRKLEKENSKMIDRIDKLEKQKADTNEKIA 1629

Query: 843  EIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRD 902
             IE EN  L  + + L+E+ +N Q  +++++         ++  D  + +  + +T+L+ 
Sbjct: 1630 NIEKENSSLISERKTLVEKVENFQDEITNLKSSLEKNDSLSSSHDELKDKFNELETELKR 1689

Query: 903  LESNLKRITHEHQTL---IVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQ 959
              + L ++  E++ L   +++ ++++  +E E +T  ++    + V+N+  + N E    
Sbjct: 1690 NLTELNKLESENKQLSDKVIEHEEKVSMVEKELSTAQKTLKEREDVINKLKDSNNELNKT 1749

Query: 960  LE---AQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNA 1016
            ++   A  + Y+ +I   + ++ +L K   ++ DK                + E  K   
Sbjct: 1750 IDKHGATEKHYEESITKKDSDIAQLKKKIKDIEDK------------LSNILEEKAKAAM 1797

Query: 1017 LLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQ 1076
            L+ Q +++       + N++      +  Y SK +   +KL++ EE  + V +   +S++
Sbjct: 1798 LMTQLEKD----KTDLKNSESELKQELEHYRSKYSSLESKLKSTEEAKKHVEE---ESRE 1850

Query: 1077 HNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXX 1136
             ++ + + ++   D++K   E  ++ EM+  K +  +++     +   +N  D       
Sbjct: 1851 QHQSMSLDLKATKDKLKS-AEISIS-EMDAIKKQVELLTKENVDLKSKSNKADNSAKLKS 1908

Query: 1137 XXXXXLKVQEEEEF-IQERSVLQEQSAKLNTELQECYTKIIQ-LETLNTELTGHD 1189
                  K  E+ +  + +RS L +    L TEL E  +K  + L  L  EL+  +
Sbjct: 1909 ELDELKKENEKLQLKVNDRSELDDLML-LVTELDEKNSKYREKLSELGVELSSDE 1962



 Score =  118 bits (283), Expect = 2e-24
 Identities = 168/844 (19%), Positives = 358/844 (42%), Gaps = 62/844 (7%)

Query: 765  ENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELV 824
            E ++++ +  KS +  LE   +   ++R  LE++   L S  +  ++   E   +   + 
Sbjct: 700  EEVQNQCTSLKSHLSELEIQSS---EKRSQLEKQIKSLTSNFEASEQLKKELEDKLSTIS 756

Query: 825  NRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKAN 884
             +   L       +K+L EI   N  L++ N    +  + L+  L+D ++    + ++  
Sbjct: 757  EKQQTLESEYEEKKKELAEITANNTSLEQLNTQKEKLTEELKKQLADTKEKLTQMEKQVK 816

Query: 885  RTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFN--TQIESAIRD 942
              +L+E +  K +  +  +  +L  +  E Q L    K+  +DLE   N  T+ E+ ++D
Sbjct: 817  --ELSEHKE-KNEQGINKMNRDLFSLQREKQKLEEDNKQSKKDLEKTKNDFTKQETKLKD 873

Query: 943  K-KVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELN---KMNLELIDKHVQKQQT 998
            + K      ++  E + +   Q +EY + I+N+   + E     K +   + K  +K + 
Sbjct: 874  QIKAKEILIKETTEKLNEATTQSKEYHDKIQNITSEMNEWQAKYKSHDTFVAKLTEKLKA 933

Query: 999  QSPDYTEQYINE---INKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTT 1055
             +  + E         ++L  + +++D  I A+  +  + +  Y +M S+ +  L + T 
Sbjct: 934  LATSFKELQAERDTIKSELEKITQERDTNIAAITSEKKSLEELYKNMESEKDGLLKKITE 993

Query: 1056 KLENMEEEMQRV--SKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMI 1113
                +E + ++    K  L+S+     L+I   + + +  + +  +L       K +   
Sbjct: 994  LETGIESDNKKFEDEKSALESETKRLTLEIAEFKSNAEKLDTERERLQTLTESYKEKLNE 1053

Query: 1114 ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYT 1173
             +S+I+  + D NN+                Q+ E    E S L+ +  +L T L E  +
Sbjct: 1054 ANSSIDEKNKDLNNIQ---------------QQIEGSQSEISTLKAEITQLKTSLNEEKS 1098

Query: 1174 KIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGF 1233
                LE L  E   +    Q+++ QL+ +++ L +EN + L   + L+      V +   
Sbjct: 1099 TRKALEKLKEENETYIQSAQDELLQLQKEVDLLKSENKDALDNNSSLKQKYDELVKE--L 1156

Query: 1234 EIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVT 1293
            E+  L  + L+    +      +L   + +  +  ++L + + +S QE    I  +  + 
Sbjct: 1157 ELKNLESKQLSDNSLNLNSKIEQLEGDIKSKYNTIKELEEKLSTSLQEREENIANIADIE 1216

Query: 1294 SLQNKLQD-------KEEHLRNLQEKYADVINQIEI-LRSEIEDEKVAFXXXXXXXXXXX 1345
               N  ++       K E LR   EK      ++E  L+S  +D +              
Sbjct: 1217 LKLNSKEEQYTEQTNKLEELRISFEKKQSECKELESKLKSSNDDLQEKNRLTKELQKNLD 1276

Query: 1346 XXXXXDLRTEN--QSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVL 1403
                   +TE   QS  + ++Q      EE  QL K +            R+ D  AK+ 
Sbjct: 1277 SLMKDKEKTEGSLQSLLEDKKQEEKKYKEEIDQLGKENEDITKQNKELNLRLEDYSAKID 1336

Query: 1404 ELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILR 1463
                +L+L +  +   T +  + L ++  + E+ +    + E  +       +SEL    
Sbjct: 1337 AKDEELKLANDAV-ASTKKKMLKLEEKIKDLEDTQHIFKDSENSL-------KSELEKTA 1388

Query: 1464 LKMHE-NANHYETMQKESEIERV--KLIEELNVKITESVSLNKQVAELNKALEEEVAKTN 1520
            L+M+E  +++   ++ ++E++R   KLIEE N +  E   L  +VA+L   L+ + + T 
Sbjct: 1389 LEMNELRSDNDNIIKLKNELQRTNDKLIEE-NKRTEE--KLRSEVAKLKDELKTK-SDTF 1444

Query: 1521 EMQTALENQEIE--IVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNK 1578
            E +  L N++    I   +++I++L+  V    S+  K ++   D K+  + +L +   +
Sbjct: 1445 EKERKLMNEDSSTIIKEYSEKISSLEEKVETIKSEYDKEINILEDKKEVLESELSD-KKQ 1503

Query: 1579 ELLD 1582
            E++D
Sbjct: 1504 EIID 1507



 Score =  106 bits (255), Expect = 4e-21
 Identities = 173/824 (20%), Positives = 353/824 (42%), Gaps = 87/824 (10%)

Query: 813  YSEY-TIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSD 871
            ++EY TI   E   R+     HD   E   +      +E+Q +   L      L+I  S+
Sbjct: 663  FNEYFTILFKENFYRILRCFYHDPTDEPIAIVSFEAFEEVQNQCTSLKSHLSELEIQSSE 722

Query: 872  MQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTL---IVQKKKEIEDL 928
             +      + K+  ++   SE  K     ++LE  L  I+ + QTL     +KKKE+ ++
Sbjct: 723  KRSQLEKQI-KSLTSNFEASEQLK-----KELEDKLSTISEKQQTLESEYEEKKKELAEI 776

Query: 929  EIEFNTQIESAIRDKKVLNEKYEKNI----EYVTQLEAQLQEYKNNIENLNMNVEELNKM 984
                NT +E     K+ L E+ +K +    E +TQ+E Q++E   + E    N + +NKM
Sbjct: 777  TAN-NTSLEQLNTQKEKLTEELKKQLADTKEKLTQMEKQVKELSEHKEK---NEQGINKM 832

Query: 985  NLELIDKHVQKQQT-----QSPDYTEQYINEINKLNALLKQ--KDEEIIA--LNQKINNA 1035
            N +L     +KQ+      QS    E+  N+  K    LK   K +EI+     +K+N A
Sbjct: 833  NRDLFSLQREKQKLEEDNKQSKKDLEKTKNDFTKQETKLKDQIKAKEILIKETTEKLNEA 892

Query: 1036 QVS---YMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQI 1092
                  Y   + +  S++ ++  K ++ +  + +++++L       +ELQ    E+D   
Sbjct: 893  TTQSKEYHDKIQNITSEMNEWQAKYKSHDTFVAKLTEKLKALATSFKELQA---ERDTIK 949

Query: 1093 KELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKV---QEEEE 1149
             EL+  K+T E +   T    I+S  + + +   N++            L+     + ++
Sbjct: 950  SELE--KITQERD---TNIAAITSEKKSLEELYKNMESEKDGLLKKITELETGIESDNKK 1004

Query: 1150 FIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTE 1209
            F  E+S L+ ++ +L  E+ E  +   +L+T    L       +E++N+  S +++ N +
Sbjct: 1005 FEDEKSALESETKRLTLEIAEFKSNAEKLDTERERLQTLTESYKEKLNEANSSIDEKNKD 1064

Query: 1210 NDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYE 1269
             +N+   +   +S IS+             K  + Q +    + E   R  L   + + E
Sbjct: 1065 LNNIQQQIEGSQSEISTL------------KAEITQLKTSLNE-EKSTRKALEKLKEENE 1111

Query: 1270 QLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIED 1329
              + S Q         +   ++V  L+++ +D  ++  +L++KY +++ ++E+    +E 
Sbjct: 1112 TYIQSAQDEL------LQLQKEVDLLKSENKDALDNNSSLKQKYDELVKELEL--KNLES 1163

Query: 1330 EKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXX 1389
            ++++                 D++++  + K+++E+   ++ E    +  +         
Sbjct: 1164 KQLS--DNSLNLNSKIEQLEGDIKSKYNTIKELEEKLSTSLQEREENI-ANIADIELKLN 1220

Query: 1390 XXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIE 1449
                +  +   K+ EL    E K SE      E    L   ND+ +   +   E +K ++
Sbjct: 1221 SKEEQYTEQTNKLEELRISFEKKQSE----CKELESKLKSSNDDLQEKNRLTKELQKNLD 1276

Query: 1450 DLTYEKE----SELAILRLKMHENANHYETMQ---KESEIERVKLIEELNVKITE-SVSL 1501
             L  +KE    S  ++L  K  E   + E +    KE+E +  K  +ELN+++ + S  +
Sbjct: 1277 SLMKDKEKTEGSLQSLLEDKKQEEKKYKEEIDQLGKENE-DITKQNKELNLRLEDYSAKI 1335

Query: 1502 NKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFA 1561
            + +  EL K   + VA T +    LE    +I  L D     ++   +  S+++K     
Sbjct: 1336 DAKDEEL-KLANDAVASTKKKMLKLEE---KIKDLEDTQHIFKDSENSLKSELEKTALEM 1391

Query: 1562 SDTKQGRDE--QLDNTM---NKELLDAVPRAELDLAMYMLHQRD 1600
            ++ +   D   +L N +   N +L++   R E  L   +   +D
Sbjct: 1392 NELRSDNDNIIKLKNELQRTNDKLIEENKRTEEKLRSEVAKLKD 1435


>UniRef50_A0CWT0 Cluster: Chromosome undetermined scaffold_3, whole
            genome shotgun sequence; n=1; Paramecium tetraurelia|Rep:
            Chromosome undetermined scaffold_3, whole genome shotgun
            sequence - Paramecium tetraurelia
          Length = 2043

 Score =  161 bits (391), Expect = 1e-37
 Identities = 257/1256 (20%), Positives = 575/1256 (45%), Gaps = 166/1256 (13%)

Query: 396  QDTDKKINKNEIAKL-EMVIQSLNKDLVDK-EYVISEKDTXXXXXXXXXXGKDTLIAQLQ 453
            Q  + KI+  E+ KL E +IQ +++D  +K E + +               K        
Sbjct: 383  QQQNNKIDDKEVEKLFEALIQLVDEDQSNKLESMQNASKFDWNKTQIKELVKSIKKRNSV 442

Query: 454  LEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQIT 513
            L+ Q H+E     +   + E + +    Q  ++ E+ +  K+  +K L +K++  ++ I+
Sbjct: 443  LQTQTHLEDQLKQYQEKSAEQLQQQQIGQGFIQSEIEE--KNQLIKQLQDKIRQQQQLIS 500

Query: 514  QLNDE---IDAANKNMIKVKSNHKLKLKQMQK--TIDNFSKVSDSNKEIVRLTEELHHLS 568
               ++   ++  ++  +K +    LK+ +  K  TI   +K S   ++I  L  E+    
Sbjct: 501  NYIEQTKLLEETHQQSMKSQEREYLKMIEELKNNTILKSNKESFYEEKISSLQLEMERKI 560

Query: 569  QKVAEL---EEEKGNLQLHLVD--YDSGR--MIESDV-YKKMI-EMENLAETRLKAISLL 619
            ++  E    +EE+   +++L+   YD  +  +   D+ YKK   E ENL E +L+     
Sbjct: 561  KEKEEFIKSKEEQQEKEIYLISEQYDKIKKDLENKDILYKKQQKEQENLFEQQLRQ---- 616

Query: 620  ESQKFDLVQELHILQQKY----DEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASK 675
            E QK++    +  L +KY    + +E ++ +I+Q Q +Q+  E+++    + ++ L    
Sbjct: 617  ECQKYE--NTIKTLDEKYQYQIENLEKQVIEINQ-QKNQI--ELETQEKIKNLENLLKKN 671

Query: 676  KELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKI-SE 734
            +E +  +  LK + E   G I+ ++  +++ +  +QN +Q+     ++ E  + E I  +
Sbjct: 672  QEESQNL--LKQNLETYEGKIEQMQIKQQNEIEGIQNRLQDQ----NQKENQNKENIYQQ 725

Query: 735  LLAKINHEEQSKI-QTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRY 793
             + +IN + + +I +        IQ +D  I+  E ++    S+    E+  +V+E  R 
Sbjct: 726  EIEQINQDYKQQINEISQNFKEIIQRKDESIKQQEQKIQDQDSK--HQEKLQSVLEQHRL 783

Query: 794  SLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKE--- 850
             LE K   +    +E  + +++   Q  E   +   L   D+  ++++ EI  + +E   
Sbjct: 784  ELESKEQSIKLLKEESSQYFTQEIQQNTESYEKQ--LEQKDQTYQQEINEINQKFQETMF 841

Query: 851  -----LQKKNQILLEENQNLQISLSDMQQ-HYNALVEKANRTDLA-ESESTKYQTQLRDL 903
                 ++++ Q + E +Q  Q  L  +++ H N   +K        E +   Y+ Q+ ++
Sbjct: 842  QKDELIKQQEQKIQELDQQYQGQLKTLEEYHKNKFQQKDEEYQKQLEQKDKDYKQQINEV 901

Query: 904  ESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNI--------E 955
              N K +  +   +I Q++++I D+E++   Q++      KV  E  E++I        +
Sbjct: 902  NQNFKEVLEQKNEIIKQQEQKIHDIELKHQEQLQILAEQHKVELESKEQSIKLLKEESSQ 961

Query: 956  YVTQ-LEAQLQEYKNNIE----NLNMNVEELNKMNLELI---DKHVQK-----------Q 996
            Y TQ L+ + + +K  +E    + N+ ++E+N+   E+I   D  +++           Q
Sbjct: 962  YFTQELQQKDETHKKQLEQKDQDHNIQIDEINQKFKEIISQKDDQIKQQEQKILDLDLNQ 1021

Query: 997  QTQSPDYTEQYINEINKLNAL----LKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQ 1052
            Q Q     EQY NE+++ +      L+QKDEE     ++IN    ++  ++   +  L Q
Sbjct: 1022 QQQLKSLEEQYKNELSQKDETNQKSLEQKDEE---YKEQINEINQNFKEILQQKDDSLKQ 1078

Query: 1053 FTTKLE----NMEEEMQRVSKQLLDSKQHNEELQILVREQDDQ--IKELKETKLTFEMNI 1106
               K++    N +++++ + +Q  +  + N+E    + EQ DQ  IK++ E    F+  +
Sbjct: 1079 QELKIQDLDLNHQQKLKTLEEQHKNQLEQNDEAYSKLLEQKDQENIKQINEISQNFKEIL 1138

Query: 1107 PKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNT 1166
             K +      T++ +    ++ +            LK+QE++++++E+  L+ +S + + 
Sbjct: 1139 EKKD-----ETMKQLEYKVSDFE------------LKLQEQQKYLEEQHKLELESKEQSI 1181

Query: 1167 ELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISS 1226
            +L     K    +    EL   D  +Q+Q++Q     + +   ND       + + +IS 
Sbjct: 1182 QL----LKEESNQYFTQELKQKDETHQKQLDQ--KDQDHIQVVND----ISYKFKEAISQ 1231

Query: 1227 AVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKI 1286
              DQ  ++  +++  +L  +E   +  + +    LS  +  ++  L+ +    +++ N+I
Sbjct: 1232 KDDQIKYQEEKIYNLNLNYQE-QLKSLQEQHNNLLSQKDETHQGQLEQIDLDHKQQINEI 1290

Query: 1287 VTMEQVTSLQNKLQDKEEHLRNLQEKYADV-INQIEILRSEIEDEKVAFXXXXXX----X 1341
                   + +  +Q K++ L+ L++K  D+ +N  E L+S ++  KV             
Sbjct: 1291 -----SQNFKEIIQQKDDSLKQLEQKIQDLDLNHQEQLKSILDQHKVELESKEQSIKLLK 1345

Query: 1342 XXXXXXXXXDLRTENQSYKQMQEQSILN----INEENAQLKKSSXXXXXXXXXXXXRVND 1397
                     +L+ +++SY++  EQ   +    INE N   K+              ++ND
Sbjct: 1346 EESSQYFTQELQQKSESYEKQLEQKDQDYKQQINEINQNFKEVLEEKEENLKQQEQKLND 1405

Query: 1398 AEA------KVLELTHQLELKDSE-----IYQKTHEY-TITLTQRNDEFENVRQQL-VEY 1444
             E       K L   H++EL+  E     + +++ +Y T  L Q+++  +   +Q+  ++
Sbjct: 1406 IELKNQEQFKSLAEQHKVELESKEQSIKLLKEESSQYFTQELQQKDETHQKQLEQIDQDH 1465

Query: 1445 EKRIEDLTYE------------KESELAILRLKMHENANHYETMQKESEIERVKLIEELN 1492
            +K+I+++               K+SE  IL L +H      ++++++ + E  +  ++L 
Sbjct: 1466 KKQIDEINQNFKEIISQKDDQIKQSESKILDLDLHYQ-QQLKSLEEQYKNEISQKDQDLK 1524

Query: 1493 VKITE-SVSLNKQVAELNKALEEEVAK----TNEMQTALENQEIEIVTLNDEITNL 1543
             +I E  ++   Q++ +++ L+EE+ +    TN++    +  + +++  +DE  NL
Sbjct: 1525 QQINEIQINYQNQISNVSQKLQEELIQNDQLTNQISLLQQIYDKQLLQKDDEYKNL 1580



 Score =  150 bits (364), Expect = 3e-34
 Identities = 264/1286 (20%), Positives = 559/1286 (43%), Gaps = 108/1286 (8%)

Query: 212  EDTKQQMTKMQENFIAMEAEWKDE--KQRLLKDIESKDVRISSLEEANKLLEAARFEISL 269
            +D KQQ+ ++ +NF  +  + KDE  KQ+  K I+ +D +    E+   +LE  R E+  
Sbjct: 732  QDYKQQINEISQNFKEI-IQRKDESIKQQEQK-IQDQDSKHQ--EKLQSVLEQHRLELES 787

Query: 270  EHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELT--KK 327
            +   +    E+                 +S E   E+K +  ++   EI    + T  +K
Sbjct: 788  KEQSIKLLKEESSQYFTQEIQQNT----ESYEKQLEQKDQTYQQEINEINQKFQETMFQK 843

Query: 328  IELLEHLNCQIRQTNKELENKLATMGT--ESKAVSSPSKKGSPLISR-KSGRNTASKMKS 384
             EL++    +I++ +++ + +L T+    ++K      +    L  + K  +   +++  
Sbjct: 844  DELIKQQEQKIQELDQQYQGQLKTLEEYHKNKFQQKDEEYQKQLEQKDKDYKQQINEVNQ 903

Query: 385  PWSQL---SSETLNQDTDKKINKNEIA---KLEMVIQSLNKDLVDKEYVISE-KDTXXXX 437
             + ++    +E + Q  ++KI+  E+    +L+++ +    +L  KE  I   K+     
Sbjct: 904  NFKEVLEQKNEIIKQQ-EQKIHDIELKHQEQLQILAEQHKVELESKEQSIKLLKEESSQY 962

Query: 438  XXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVN 497
                   KD    + QLE +       +  +    +++  I++  +Q+KQ+   +I D++
Sbjct: 963  FTQELQQKDETHKK-QLEQKDQDHNIQIDEINQKFKEI--ISQKDDQIKQQ-EQKILDLD 1018

Query: 498  VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSN-HKLKLKQMQKTIDNFSKVSDSN-- 554
            +    ++LKS EEQ      + D  N+  ++ K   +K ++ ++ +      +  D +  
Sbjct: 1019 LNQQ-QQLKSLEEQYKNELSQKDETNQKSLEQKDEEYKEQINEINQNFKEILQQKDDSLK 1077

Query: 555  -KEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRL 613
             +E+     +L+H  QK+  LEE+  N QL   D         + Y K++E ++  +  +
Sbjct: 1078 QQELKIQDLDLNH-QQKLKTLEEQHKN-QLEQND---------EAYSKLLEQKD--QENI 1124

Query: 614  KAISLLESQKFDLVQELHILQQKYDEVEDKLADIS-QLQSDQ-VCSEIKSVHLEEQIDAL 671
            K I+ + SQ F  + E     +   ++E K++D   +LQ  Q    E   + LE +  ++
Sbjct: 1125 KQINEI-SQNFKEILEKK--DETMKQLEYKVSDFELKLQEQQKYLEEQHKLELESKEQSI 1181

Query: 672  SASKKEL-ALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAE 730
               K+E      + LK   E     +   + D   ++N +    +E +   D   K   E
Sbjct: 1182 QLLKEESNQYFTQELKQKDETHQKQLDQKDQDHIQVVNDISYKFKEAISQKDDQIKYQEE 1241

Query: 731  KISELLAKINHEEQSK-IQTQFG--IDAKIQERDLYIENIESELSKYKSRICR-LEESIA 786
            KI  L   +N++EQ K +Q Q    +  K +     +E I+ +  +  + I +  +E I 
Sbjct: 1242 KIYNL--NLNYQEQLKSLQEQHNNLLSQKDETHQGQLEQIDLDHKQQINEISQNFKEIIQ 1299

Query: 787  VMEDRRYSLERKADQLGSYLQEKQKAY-SEYTIQEDELVNRLAVLMDHDRVVEKQLLEIE 845
              +D    LE+K   L    QE+ K+   ++ ++ +     + +L +       Q L+ +
Sbjct: 1300 QKDDSLKQLEQKIQDLDLNHQEQLKSILDQHKVELESKEQSIKLLKEESSQYFTQELQQK 1359

Query: 846  HENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLES 905
             E+ E Q     L +++Q+ +  ++++ Q++  ++E+    +L + E      +L++ E 
Sbjct: 1360 SESYEKQ-----LEQKDQDYKQQINEINQNFKEVLEEKEE-NLKQQEQKLNDIELKNQEQ 1413

Query: 906  NLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQ-LEAQL 964
              K +  +H+  +  K++ I+ L+ E +      ++ K   +E ++K +E + Q  + Q+
Sbjct: 1414 -FKSLAEQHKVELESKEQSIKLLKEESSQYFTQELQQK---DETHQKQLEQIDQDHKKQI 1469

Query: 965  QEYKNNI-ENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDE 1023
             E   N  E ++   +++ +   +++D  +  QQ Q     EQY NEI+       QKD+
Sbjct: 1470 DEINQNFKEIISQKDDQIKQSESKILDLDLHYQQ-QLKSLEEQYKNEIS-------QKDQ 1521

Query: 1024 EIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSK--QHNEEL 1081
            +   L Q+IN  Q++Y + +S+   KL +   + + +  ++  + +Q+ D +  Q ++E 
Sbjct: 1522 D---LKQQINEIQINYQNQISNVSQKLQEELIQNDQLTNQISLL-QQIYDKQLLQKDDEY 1577

Query: 1082 QILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXX 1141
            + L+ E  +    +   K+   +     E  I++ T+E        V             
Sbjct: 1578 KNLILEISENHLRMIINKMNLIITNFNNE-QILNLTLENEQLREQIVTENKVTAQQQQIY 1636

Query: 1142 LKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKS 1201
            +K    ++F Q++  L  Q+ KL  E     T     + +   L        EQI++LK 
Sbjct: 1637 IK----DDFNQQQEQLSNQNHKLINEDSNNQTNT-DFQIIEENLKSLINEQNEQISELKQ 1691

Query: 1202 K----LEQLNTENDNLLSTVAELRSSISSAVD--QRGFEIAELWKQHLAQREADFQKTEH 1255
            K       + +   N  S   EL+S     +D   + +E  +   Q+  ++  +  + ++
Sbjct: 1692 KDFDNQNIIESLKQNFESKQQELQSKYQGQIDACMKDYEDEKDKMQNQFKQVQNDLEEKY 1751

Query: 1256 ELRV-QLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDK-EEHLRNLQEKY 1313
            +L + +L    SK    +  ++SS Q    ++ +  Q T L+  +Q + EE L+    + 
Sbjct: 1752 KLEIFELLETISKLRFQIQDIESSLQNTNAELFS--QQTKLKQIIQLQFEEQLKKQASEK 1809

Query: 1314 ADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRT---ENQSYKQMQEQSILNI 1370
             ++I+  E LR +  ++ +                  DL+    E      + + +  N 
Sbjct: 1810 DEIISNFEKLRYQY-NQTLQLNQQKDSEIQEQKSFIEDLKKNIDETNQLLSLPKSTYNNF 1868

Query: 1371 NEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQR 1430
             + N + +K               + D    +L+L +QL LK+SEIY    ++    +QR
Sbjct: 1869 KQLNIKFEKEKVDQTGLTQNTAKELQD---NLLQLRNQLILKESEIYSLRLQFIDANSQR 1925

Query: 1431 NDEFENVRQQLVEYEKRIEDL-TYEK 1455
             + F  V+  + E +   E L TY++
Sbjct: 1926 LNYFYQVQNYIKEMKLMSEKLQTYDQ 1951



 Score =  132 bits (318), Expect = 1e-28
 Identities = 185/921 (20%), Positives = 401/921 (43%), Gaps = 80/921 (8%)

Query: 680  LVIENLKLDKEQLYGTIKDLENDK-EDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAK 738
            L++ N++LDK   + + +D +  K  + + + +  +Q+     +K++    EK+ E L +
Sbjct: 344  LILRNIQLDKFTAFLSQEDEKKIKYRNSIAQKEQQLQQQQQQNNKIDDKEVEKLFEALIQ 403

Query: 739  INHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERK 798
            +  E+QS         +K       I+ +   + K  S    L+    + +  +   E+ 
Sbjct: 404  LVDEDQSNKLESMQNASKFDWNKTQIKELVKSIKKRNS---VLQTQTHLEDQLKQYQEKS 460

Query: 799  ADQLGSYLQEKQKAYSEYTIQE-DELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQI 857
            A+QL    Q+  + + +  I+E ++L+ +L      D++ ++Q L     N   Q K   
Sbjct: 461  AEQLQQ--QQIGQGFIQSEIEEKNQLIKQL-----QDKIRQQQQL---ISNYIEQTK--- 507

Query: 858  LLEENQNLQISLSDMQQHYNALVEK-ANRTDLAESESTKYQTQLRDLESNLKRITHEHQT 916
            LLEE    Q S+   ++ Y  ++E+  N T L  ++ + Y+ ++  L+  ++R   E + 
Sbjct: 508  LLEETH--QQSMKSQEREYLKMIEELKNNTILKSNKESFYEEKISSLQLEMERKIKEKEE 565

Query: 917  LIVQKKKEIED---LEIEFNTQIESAIRDKKVLNEKYEKNIE--YVTQLEAQLQEYKNNI 971
             I  K+++ E    L  E   +I+  + +K +L +K +K  E  +  QL  + Q+Y+N I
Sbjct: 566  FIKSKEEQQEKEIYLISEQYDKIKKDLENKDILYKKQQKEQENLFEQQLRQECQKYENTI 625

Query: 972  ENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQK 1031
            + L    +E  +  +E ++K V +   Q      +   +I  L  LLK+  EE       
Sbjct: 626  KTL----DEKYQYQIENLEKQVIEINQQKNQIELETQEKIKNLENLLKKNQEE------- 674

Query: 1032 INNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQ-RVSKQLLDSKQHNEEL--QILVREQ 1088
               +Q      +  YE K+ Q   K +N  E +Q R+  Q     Q+ E +  Q + +  
Sbjct: 675  ---SQNLLKQNLETYEGKIEQMQIKQQNEIEGIQNRLQDQNQKENQNKENIYQQEIEQIN 731

Query: 1089 DDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEE 1148
             D  +++ E    F+  I + +  I     E    D ++              L+++ +E
Sbjct: 732  QDYKQQINEISQNFKEIIQRKDESIKQQ--EQKIQDQDSKHQEKLQSVLEQHRLELESKE 789

Query: 1149 EFIQERSVLQEQSAKLNT-ELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLN 1207
            + I+   +L+E+S++  T E+Q+        E+   +L   D   Q++IN++  K ++  
Sbjct: 790  QSIK---LLKEESSQYFTQEIQQ------NTESYEKQLEQKDQTYQQEINEINQKFQETM 840

Query: 1208 TENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESK 1267
             + D L   + +    I     Q   ++  L + H    +  FQ+ + E + QL   +  
Sbjct: 841  FQKDEL---IKQQEQKIQELDQQYQGQLKTLEEYH----KNKFQQKDEEYQKQLEQKDKD 893

Query: 1268 YEQLLDSVQSSTQ---EETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILR 1324
            Y+Q ++ V  + +   E+ N+I+  ++      +L+ +E+ L+ L E++   +   E   
Sbjct: 894  YKQQINEVNQNFKEVLEQKNEIIKQQEQKIHDIELKHQEQ-LQILAEQHKVELESKEQSI 952

Query: 1325 SEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYK--QMQEQSILNINEENAQLKKSSX 1382
              +++E   +                + + ++ + +  ++ ++    I++++ Q+K+   
Sbjct: 953  KLLKEESSQYFTQELQQKDETHKKQLEQKDQDHNIQIDEINQKFKEIISQKDDQIKQQEQ 1012

Query: 1383 XXXXXXXXXXXRVNDAEAKVL-ELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQ- 1440
                       ++   E +   EL+ + E     + QK  EY   + + N  F+ + QQ 
Sbjct: 1013 KILDLDLNQQQQLKSLEEQYKNELSQKDETNQKSLEQKDEEYKEQINEINQNFKEILQQK 1072

Query: 1441 ---LVEYEKRIEDLTYEKESELAIL----RLKMHENANHYETMQKESEIERVKLIEELNV 1493
               L + E +I+DL    + +L  L    + ++ +N   Y  + ++ + E +K I E++ 
Sbjct: 1073 DDSLKQQELKIQDLDLNHQQKLKTLEEQHKNQLEQNDEAYSKLLEQKDQENIKQINEISQ 1132

Query: 1494 KITESV-SLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSS 1552
               E +   ++ + +L   + +   K  E Q  LE Q    + L  +  ++Q +   S+ 
Sbjct: 1133 NFKEILEKKDETMKQLEYKVSDFELKLQEQQKYLEEQ--HKLELESKEQSIQLLKEESNQ 1190

Query: 1553 KIQKHVSFASDTKQGRDEQLD 1573
               + +    +T Q + +Q D
Sbjct: 1191 YFTQELKQKDETHQKQLDQKD 1211



 Score =  109 bits (263), Expect = 5e-22
 Identities = 147/784 (18%), Positives = 341/784 (43%), Gaps = 39/784 (4%)

Query: 807  QEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLE--IEHENKELQKKNQILLEENQN 864
            +++ KA  E  + E + +    + +D       Q  E  I++ N   QK+ Q+  ++ QN
Sbjct: 327  RDQYKAIQEINVDEFQRLILRNIQLDKFTAFLSQEDEKKIKYRNSIAQKEQQLQQQQQQN 386

Query: 865  LQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITH--EHQTLIVQKK 922
             +I   ++++ + AL++  +     + ES +  ++    ++ +K +    + +  ++Q +
Sbjct: 387  NKIDDKEVEKLFEALIQLVDEDQSNKLESMQNASKFDWNKTQIKELVKSIKKRNSVLQTQ 446

Query: 923  KEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELN 982
              +ED   ++  +    ++ +++     +  IE   QL  QLQ+     + L  N  E  
Sbjct: 447  THLEDQLKQYQEKSAEQLQQQQIGQGFIQSEIEEKNQLIKQLQDKIRQQQQLISNYIEQT 506

Query: 983  KMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSM 1042
            K+   L + H Q  ++Q  +Y +  I E+ K N +LK   E      +KI++ Q+     
Sbjct: 507  KL---LEETHQQSMKSQEREYLKM-IEEL-KNNTILKSNKESF--YEEKISSLQLEMERK 559

Query: 1043 VSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTF 1102
            + + E  +    +K E  E+E+  +S+Q    K+  E   IL ++Q  + + L E +L  
Sbjct: 560  IKEKEEFI---KSKEEQQEKEIYLISEQYDKIKKDLENKDILYKKQQKEQENLFEQQLRQ 616

Query: 1103 EMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSA 1162
            E    K E   I +  E       N++            ++++ +E+     ++L++   
Sbjct: 617  ECQ--KYEN-TIKTLDEKYQYQIENLEKQVIEINQQKNQIELETQEKIKNLENLLKKNQE 673

Query: 1163 KLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLN-TENDNLLSTVAELR 1221
            +    L++       LET   ++    +  Q +I  ++++L+  N  EN N  +   +  
Sbjct: 674  ESQNLLKQ------NLETYEGKIEQMQIKQQNEIEGIQNRLQDQNQKENQNKENIYQQEI 727

Query: 1222 SSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDS--VQSST 1279
              I+    Q+  EI++ +K+ + +++   ++ E +++ Q S  + K + +L+   ++  +
Sbjct: 728  EQINQDYKQQINEISQNFKEIIQRKDESIKQQEQKIQDQDSKHQEKLQSVLEQHRLELES 787

Query: 1280 QEETNKIVTMEQVTSLQNKL-QDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXX 1338
            +E++ K++  E       ++ Q+ E + + L++K  D   Q EI     + ++  F    
Sbjct: 788  KEQSIKLLKEESSQYFTQEIQQNTESYEKQLEQK--DQTYQQEINEINQKFQETMFQKDE 845

Query: 1339 XXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDA 1398
                        D + + Q  K ++E       +++ + +K               VN  
Sbjct: 846  LIKQQEQKIQELDQQYQGQ-LKTLEEYHKNKFQQKDEEYQKQLEQKDKDYKQQINEVNQN 904

Query: 1399 EAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESE 1458
              +VLE  +++ +K  E  QK H+  I L  +        Q  VE E + + +   KE  
Sbjct: 905  FKEVLEQKNEI-IKQQE--QKIHD--IELKHQEQLQILAEQHKVELESKEQSIKLLKEES 959

Query: 1459 LAILRLKMHE-NANHYETMQKESEIERVKLIEELNVKITESVS-LNKQVAELNKALEEEV 1516
                  ++ + +  H + ++++ +   ++ I+E+N K  E +S  + Q+ +  + + +  
Sbjct: 960  SQYFTQELQQKDETHKKQLEQKDQDHNIQ-IDEINQKFKEIISQKDDQIKQQEQKILDLD 1018

Query: 1517 AKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTM 1576
                +   +LE Q    ++  DE TN +++ +      ++      + K+   ++ D+  
Sbjct: 1019 LNQQQQLKSLEEQYKNELSQKDE-TNQKSLEQKDEEYKEQINEINQNFKEILQQKDDSLK 1077

Query: 1577 NKEL 1580
             +EL
Sbjct: 1078 QQEL 1081



 Score = 87.0 bits (206), Expect = 4e-15
 Identities = 181/927 (19%), Positives = 408/927 (44%), Gaps = 89/927 (9%)

Query: 212  EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRI-SSLEEANKLLE--AARFEIS 268
            E  K Q+ +  E +  +  +   E  + + +I      I    +E  K LE   + FE+ 
Sbjct: 1099 EQHKNQLEQNDEAYSKLLEQKDQENIKQINEISQNFKEILEKKDETMKQLEYKVSDFELK 1158

Query: 269  LEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKI 328
            L+  +   E EQ              L ++S +   +E  + +E    ++    +    I
Sbjct: 1159 LQEQQKYLE-EQHKLELESKEQSIQLLKEESNQYFTQELKQKDETHQKQLDQKDQ--DHI 1215

Query: 329  ELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQ 388
            +++  ++ + ++   + ++++     E K  +        L S +   N     K    Q
Sbjct: 1216 QVVNDISYKFKEAISQKDDQIKYQ--EEKIYNLNLNYQEQLKSLQEQHNNLLSQKDETHQ 1273

Query: 389  LSSETLNQDTDKKINKNEIAK-LEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDT 447
               E +  D D K   NEI++  + +IQ  +  L   E  I + D            +  
Sbjct: 1274 GQLEQI--DLDHKQQINEISQNFKEIIQQKDDSLKQLEQKIQDLDLNHQEQLKSILDQHK 1331

Query: 448  LIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQ-EQLKQELNDEIKDVN--VKDLIE- 503
            +  + + +  + ++  S  +     +  +E  + Q EQ  Q+   +I ++N   K+++E 
Sbjct: 1332 VELESKEQSIKLLKEESSQYFTQELQQKSESYEKQLEQKDQDYKQQINEINQNFKEVLEE 1391

Query: 504  KLKSAEEQITQLNDEIDAANKNMIK-VKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTE 562
            K ++ ++Q  +LND I+  N+   K +   HK++L+  +++I    +  +S++   +  +
Sbjct: 1392 KEENLKQQEQKLND-IELKNQEQFKSLAEQHKVELESKEQSIKLLKE--ESSQYFTQELQ 1448

Query: 563  ELHHLSQKVAELEEEKGNLQLHLVDYDSGRMI--ESDVYK----KMIEMENLAETRLKAI 616
            +     QK  E  ++    Q+  ++ +   +I  + D  K    K+++++   + +LK  
Sbjct: 1449 QKDETHQKQLEQIDQDHKKQIDEINQNFKEIISQKDDQIKQSESKILDLDLHYQQQLK-- 1506

Query: 617  SLLESQKFDLVQELHILQQKYDEVE----DKLADISQ------LQSDQVCSEIKSVH--L 664
            SL E  K ++ Q+   L+Q+ +E++    ++++++SQ      +Q+DQ+ ++I  +    
Sbjct: 1507 SLEEQYKNEISQKDQDLKQQINEIQINYQNQISNVSQKLQEELIQNDQLTNQISLLQQIY 1566

Query: 665  EEQIDALSASKKELALVI-EN-LKLDKEQLYGTIKDLENDKEDIMN-KLQNYIQENMDLT 721
            ++Q+       K L L I EN L++   ++   I +  N  E I+N  L+N       +T
Sbjct: 1567 DKQLLQKDDEYKNLILEISENHLRMIINKMNLIITNFNN--EQILNLTLENEQLREQIVT 1624

Query: 722  DKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESEL--SKYKSRIC 779
            +   K++A++    +    +++Q ++  Q      I E      N + ++     KS I 
Sbjct: 1625 EN--KVTAQQQQIYIKDDFNQQQEQLSNQN--HKLINEDSNNQTNTDFQIIEENLKSLIN 1680

Query: 780  RLEESIAVMEDRRYSLERKADQLGSYLQEKQKAY-SEYTIQEDELVNRLAVLMDHDRVVE 838
               E I+ ++ + +  +   + L    + KQ+   S+Y  Q D      A + D++   +
Sbjct: 1681 EQNEQISELKQKDFDNQNIIESLKQNFESKQQELQSKYQGQID------ACMKDYEDEKD 1734

Query: 839  KQLLEIEHENKELQKKNQI----LLEENQNLQISLSDMQQHYNALVEKANRTDLAESEST 894
            K   + +    +L++K ++    LLE    L+  + D++      ++  N    ++    
Sbjct: 1735 KMQNQFKQVQNDLEEKYKLEIFELLETISKLRFQIQDIESS----LQNTNAELFSQQTKL 1790

Query: 895  KYQTQLRDLESNLKRITHEHQTLI--VQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEK 952
            K   QL+  E  LK+   E   +I   +K +   +  ++ N Q +S I+++K   E  +K
Sbjct: 1791 KQIIQLQ-FEEQLKKQASEKDEIISNFEKLRYQYNQTLQLNQQKDSEIQEQKSFIEDLKK 1849

Query: 953  NIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEIN 1012
            NI+   QL +  +   NN + LN+  E+      E +D+    Q T      ++  + + 
Sbjct: 1850 NIDETNQLLSLPKSTYNNFKQLNIKFEK------EKVDQTGLTQNT-----AKELQDNLL 1898

Query: 1013 KLNALLKQKDEEIIALNQKI---NNAQVSYMSMVSDYESKLAQFTTKLENMEE-EMQRVS 1068
            +L   L  K+ EI +L  +    N+ +++Y   V +Y  ++   + KL+  ++ ++Q++ 
Sbjct: 1899 QLRNQLILKESEIYSLRLQFIDANSQRLNYFYQVQNYIKEMKLMSEKLQTYDQSDVQQI- 1957

Query: 1069 KQLLDSKQHNEELQILVREQDDQIKEL 1095
                 +  + E++++L +  ++Q+  L
Sbjct: 1958 -----TSYYEEKIKLLDQSYEEQMNRL 1979



 Score = 45.2 bits (102), Expect = 0.015
 Identities = 107/542 (19%), Positives = 214/542 (39%), Gaps = 48/542 (8%)

Query: 212  EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271
            +  KQ  +K+ +  +  + + K  +++   +I  KD  +   ++ N++    + +IS   
Sbjct: 1485 DQIKQSESKILDLDLHYQQQLKSLEEQYKNEISQKDQDLK--QQINEIQINYQNQISNVS 1542

Query: 272  SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELL 331
             KL +EL Q                KQ ++   E K  I E     +  +      I + 
Sbjct: 1543 QKLQEELIQNDQLTNQISLLQQIYDKQLLQKDDEYKNLILEISENHLRMIINKMNLI-IT 1601

Query: 332  EHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSS 391
               N QI     E E     + TE+K  +   +     I  K   N   + +   S  + 
Sbjct: 1602 NFNNEQILNLTLENEQLREQIVTENKVTAQQQQ-----IYIKDDFN---QQQEQLSNQNH 1653

Query: 392  ETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQ 451
            + +N+D++ + N +     +++ ++L   + ++   ISE                     
Sbjct: 1654 KLINEDSNNQTNTD----FQIIEENLKSLINEQNEQISELKQKDFDNQNIIESLKQNFES 1709

Query: 452  LQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELND--EIKDVNVKDLIEKLKSAE 509
             Q E Q   +G  +     + ED  +  K+Q Q KQ  ND  E   + + +L+E +    
Sbjct: 1710 KQQELQSKYQG-QIDACMKDYEDEKD--KMQNQFKQVQNDLEEKYKLEIFELLETISKLR 1766

Query: 510  EQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQ 569
             QI  +   +   N  +   ++  K ++ Q+Q   +   K +    EI+   E+L +   
Sbjct: 1767 FQIQDIESSLQNTNAELFSQQTKLK-QIIQLQFE-EQLKKQASEKDEIISNFEKLRYQYN 1824

Query: 570  KVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISL-LESQKFDLVQ 628
            +  +L ++K +       +        D   +++ +        K +++  E +K D   
Sbjct: 1825 QTLQLNQQKDSEIQEQKSFIEDLKKNIDETNQLLSLPKSTYNNFKQLNIKFEKEKVD--- 1881

Query: 629  ELHILQQKYDEVEDKLADI-SQLQSDQVCSEIKSVHLEEQIDALSASK----------KE 677
            +  + Q    E++D L  + +QL   +  SEI S+ L+  IDA S             KE
Sbjct: 1882 QTGLTQNTAKELQDNLLQLRNQLILKE--SEIYSLRLQF-IDANSQRLNYFYQVQNYIKE 1938

Query: 678  LALVIENLKL----DKEQLYG----TIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSA 729
            + L+ E L+     D +Q+       IK L+   E+ MN+L   +++N D     +  S+
Sbjct: 1939 MKLMSEKLQTYDQSDVQQITSYYEEKIKLLDQSYEEQMNRLFQQLKQNQDKEQIAQSQSS 1998

Query: 730  EK 731
            ++
Sbjct: 1999 QQ 2000


>UniRef50_A0CZI7 Cluster: Chromosome undetermined scaffold_32, whole
            genome shotgun sequence; n=3; Paramecium tetraurelia|Rep:
            Chromosome undetermined scaffold_32, whole genome shotgun
            sequence - Paramecium tetraurelia
          Length = 1837

 Score =  160 bits (389), Expect = 3e-37
 Identities = 223/1119 (19%), Positives = 506/1119 (45%), Gaps = 121/1119 (10%)

Query: 481  VQEQLKQELNDEIK--DVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLK 538
            +Q+Q++Q+L   ++   + +K   E L   E+Q       I   +K  ++V +N  L LK
Sbjct: 472  IQQQIQQQLAYALQCQGLVMKTFYENLTLKEQQ-----GAIQTVSKVQVQVDTNLNL-LK 525

Query: 539  QMQKTIDN-------FSKVSDS--NKEIVRLTE--ELHHLSQKVAELEEEKGNLQLHLVD 587
             + +T+ N       F +  D   N + V L +  EL  LS+   +L  E+    + + D
Sbjct: 526  DIVETVQNSLNERRQFQQQLDLQFNSQYVTLDKFKELETLSEYKEKLLSEQTQKLVFMED 585

Query: 588  YDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADI 647
                + IE  + +K+ E         K + + + Q  DL  ++  L Q+      +L ++
Sbjct: 586  QI--KEIEKQILQKLEENGITFNENDKVVDVRDQQIQDLKTKITDLNQELQNSNQELKEL 643

Query: 648  SQLQSDQVCSEIKS-----VHLEEQIDA-LSASKKELALVIENLKLDKEQLYGTIKDLEN 701
            S + S+QV  +++      V+ +++I++    ++ +++   +N K     L   +  L++
Sbjct: 644  S-INSEQVIQQLRFENQQIVNQKQEIESNYELTQTQISEFQDNSKQQIINLEQQLSQLQD 702

Query: 702  DKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERD 761
                  N+ Q   Q+N DL  K+E    +        I ++E+ K+     +D  I + D
Sbjct: 703  QNSQYSNQYQQLNQQNEDLKYKIENEEHQNKQLTQELIQNQEKLKL-----LDQIIVDND 757

Query: 762  LYIENIESELSKYKSRICRLEESI----AVMEDRRYSLERKADQLGSYLQEKQKAYSEYT 817
            + I+  + +L+ Y+S I +L+++I    A ++  + S+ +   +  +  QE  K  +E T
Sbjct: 758  IAIQEFKQQLTSYESIIIQLKKNINDQNANLQLNQQSISQLELENANLKQECSKQQNELT 817

Query: 818  IQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYN 877
            + ++++   ++ L + ++ +  QL   + +N+ LQ +N +L + NQ +Q  +  +    N
Sbjct: 818  LMQEQVSLSMSKLENSEQELFSQLQLSQRDNQNLQNENSLLSKANQEMQSEMDVLILELN 877

Query: 878  ALVEKANRTDLA-ESESTKYQTQL--RDLESNLKRITHE--HQTLIVQKKKEIEDLEIEF 932
            +  E    T +  + +  KY+ ++     +S ++R T E  +Q  I Q+KK+ E L  +F
Sbjct: 878  SKTEDLQNTQIQLQQKQQKYEQEIIIYQQKSQIERSTLEKDYQEQIKQQKKDFELLLFQF 937

Query: 933  NTQIESAIR--DKKVLNEKYEKNIEYVTQLEAQLQ-EYKNNIENLNMNVEELNKMNLELI 989
            NT+    +   ++++L+  Y    +     E+Q Q E++ N+ N  +  E    + LE +
Sbjct: 938  NTKQSCDLNKLNQEILSLNYIIKEKETNNTESQSQQEFQINLLNQKIQKETQRALQLESL 997

Query: 990  DKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESK 1049
               ++ Q+ +  +  ++ ++ I+ L   L+ K   I   +   N     Y+S+ +  E K
Sbjct: 998  ---LEGQKNEFQEIQKEQMSSIDLLQKQLESKQAVIQETSDHYNQVHELYLSLQARMEQK 1054

Query: 1050 ----------LAQFTTKLENMEEEMQRVSKQLLDSKQHN-EELQILVREQDDQIKELKET 1098
                      + Q  +KLE+  +E+Q++ ++++  +  N +    +  +Q  +++++ + 
Sbjct: 1055 DLVNSELKRDILQNKSKLESQTKEIQQLQQKVISIENENLQSRNTMEIQQQGKLQDMTQ- 1113

Query: 1099 KLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQ 1158
            KL+ +M   +T   + +  I  ++D    ++            L+ Q++ E   + ++LQ
Sbjct: 1114 KLSIKM---RTIEQLTAEKIN-LNDKIKEIECESNKNKQTICLLE-QQQHESQNQNNLLQ 1168

Query: 1159 EQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVA 1218
             Q   LN EL +   K  ++  L  EL+  + V  +     K + +Q+  +N+ L   ++
Sbjct: 1169 AQIQSLNNELNQ---KEQEIGFLQQELSKQNQVLDKSSEIYKKETDQMEIDNNILKKQLS 1225

Query: 1219 ELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSS 1278
            + +  I     +    + +L    L +++ D      +L++QL+   +  +Q L+     
Sbjct: 1226 DKQKDIHKLEQKLNATLNDL---QLKEQQID------QLKLQLNHLNTNLQQQLE----- 1271

Query: 1279 TQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXX 1338
                    +T +    L+ ++Q   +H+ +  E+   +  +++  ++++++ K A     
Sbjct: 1272 --------LTTKDNLLLKKEIQQLNQHIESQHEEIDQMRIELDQKQTQVDENKSAVKKLT 1323

Query: 1339 XXXXXXXXXXXXDL-RTENQSYKQMQEQ-SILNINEENAQLKKSSXXXXXXXXXXXXRVN 1396
                         L R E+Q  K++QE    L+I+++  Q K                V 
Sbjct: 1324 KQLELEIKQYSLHLKRNEDQHKKEVQELVDQLDIHQKQLQQKDLI-------------VE 1370

Query: 1397 DAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKE 1456
                +V  L    E K+       H+    + Q  D+ ++ + +  +  + +E+   + +
Sbjct: 1371 SLNKQVNGLQCAFETKED----LNHQTQKDIQQLKDKLKSDQNKFTKIIQSLENANNQLK 1426

Query: 1457 SELAILRLKMHENANHYETMQKESEI---------ERVKLIEELNVKITESVSLNKQVAE 1507
            S+L     ++ ENA+ Y+++QK++++         E+  L++E   ++   +    Q+ E
Sbjct: 1427 SQLEESSHQIQENAHKYQSVQKQNDLQSIQFNEQQEKYTLLKEQFTRLESQMKQESQIRE 1486

Query: 1508 LNKALEEEVAK-TNEMQTALENQEIEIVTLNDEITNLQN 1545
                + ++V K  NE++  ++ ++  IV L   +  LQN
Sbjct: 1487 QYSHIADKVTKENNELKQKIDKKQQIIVQLESAL--LQN 1523



 Score =  131 bits (317), Expect = 1e-28
 Identities = 230/1172 (19%), Positives = 527/1172 (44%), Gaps = 125/1172 (10%)

Query: 476  NEIAKVQEQLKQEL-------NDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIK 528
            ++I ++++Q+ Q+L       N+  K V+V+D  ++++  + +IT LN E+  +N+ + +
Sbjct: 585  DQIKEIEKQILQKLEENGITFNENDKVVDVRD--QQIQDLKTKITDLNQELQNSNQELKE 642

Query: 529  VKSNHKLKLKQMQ---KTIDNFSKVSDSNKEIVR--LTEELHHLSQKVAELEEEKGNLQL 583
            +  N +  ++Q++   + I N  +  +SN E+ +  ++E   +  Q++  LE++   LQ 
Sbjct: 643  LSINSEQVIQQLRFENQQIVNQKQEIESNYELTQTQISEFQDNSKQQIINLEQQLSQLQD 702

Query: 584  HLVDYDSGRMI---ESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHI-------- 632
                Y +       +++  K  IE E     +L    +   +K  L+ ++ +        
Sbjct: 703  QNSQYSNQYQQLNQQNEDLKYKIENEEHQNKQLTQELIQNQEKLKLLDQIIVDNDIAIQE 762

Query: 633  LQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSAS-KKELALVIENLKLDKEQ 691
             +Q+    E  +  + +  +DQ  +   +     Q++  +A+ K+E +     L L +EQ
Sbjct: 763  FKQQLTSYESIIIQLKKNINDQNANLQLNQQSISQLELENANLKQECSKQQNELTLMQEQ 822

Query: 692  LYGTIKDLENDKEDIMNKLQNYIQENMDLTDK---LEKMSAEKISE---LLAKINHEEQS 745
            +  ++  LEN ++++ ++LQ   ++N +L ++   L K + E  SE   L+ ++N + + 
Sbjct: 823  VSLSMSKLENSEQELFSQLQLSQRDNQNLQNENSLLSKANQEMQSEMDVLILELNSKTED 882

Query: 746  KIQTQFGIDAKIQ--ERDLYIENIESELSK------YKSRICRLEESIAVME---DRRYS 794
               TQ  +  K Q  E+++ I   +S++ +      Y+ +I + ++   ++    + + S
Sbjct: 883  LQNTQIQLQQKQQKYEQEIIIYQQKSQIERSTLEKDYQEQIKQQKKDFELLLFQFNTKQS 942

Query: 795  LE-RKADQ----LGSYLQEKQKAYSEYTIQEDELVNRL--AVLMDHDRVVE-KQLLEIE- 845
             +  K +Q    L   ++EK+   +E   Q++  +N L   +  +  R ++ + LLE + 
Sbjct: 943  CDLNKLNQEILSLNYIIKEKETNNTESQSQQEFQINLLNQKIQKETQRALQLESLLEGQK 1002

Query: 846  HENKELQKKNQ----ILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQL- 900
            +E +E+QK+      +L ++ ++ Q  + +   HYN + E          +     ++L 
Sbjct: 1003 NEFQEIQKEQMSSIDLLQKQLESKQAVIQETSDHYNQVHELYLSLQARMEQKDLVNSELK 1062

Query: 901  RDLESNLKRITHEHQTL--IVQKKKEIEDLEIEFNTQIESAIRDK-KVLNEKYEKNIEYV 957
            RD+  N  ++  + + +  + QK   IE+  ++    +E   + K + + +K    +  +
Sbjct: 1063 RDILQNKSKLESQTKEIQQLQQKVISIENENLQSRNTMEIQQQGKLQDMTQKLSIKMRTI 1122

Query: 958  TQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNAL 1017
             QL A+     + I+ +     + NK  + L+++    QQ +S +       +I  LN  
Sbjct: 1123 EQLTAEKINLNDKIKEIECESNK-NKQTICLLEQ----QQHESQNQNNLLQAQIQSLNNE 1177

Query: 1018 LKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQ- 1076
            L QK++EI  L Q++     S  + V D  S++  +  + + ME +   + KQL D ++ 
Sbjct: 1178 LNQKEQEIGFLQQEL-----SKQNQVLDKSSEI--YKKETDQMEIDNNILKKQLSDKQKD 1230

Query: 1077 -HNEELQILVREQDDQIKELKETKLTFEMNIPKT-----------EGMIISSTIEPMSD- 1123
             H  E ++     D Q+KE +  +L  ++N   T           + +++   I+ ++  
Sbjct: 1231 IHKLEQKLNATLNDLQLKEQQIDQLKLQLNHLNTNLQQQLELTTKDNLLLKKEIQQLNQH 1290

Query: 1124 -DANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAK---LNTELQECYTK----- 1174
             ++ + +             +V E +  +++ +   E   K   L+ +  E   K     
Sbjct: 1291 IESQHEEIDQMRIELDQKQTQVDENKSAVKKLTKQLELEIKQYSLHLKRNEDQHKKEVQE 1350

Query: 1175 -IIQLETLNTELTGHDVVNQ---EQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQ 1230
             + QL+    +L   D++ +   +Q+N L+   E     N      + +L+  + S  DQ
Sbjct: 1351 LVDQLDIHQKQLQQKDLIVESLNKQVNGLQCAFETKEDLNHQTQKDIQQLKDKLKS--DQ 1408

Query: 1231 RGF-EIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQL-LDSVQSSTQEETNKIVT 1288
              F +I +  +    Q ++  +++ H+++     ++S  +Q  L S+Q + Q+E   ++ 
Sbjct: 1409 NKFTKIIQSLENANNQLKSQLEESSHQIQENAHKYQSVQKQNDLQSIQFNEQQEKYTLLK 1468

Query: 1289 MEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIE---DEKVAFXXXXXXXXXXX 1345
             EQ T L+++++ + +    ++E+Y+ + +++    +E++   D+K              
Sbjct: 1469 -EQFTRLESQMKQESQ----IREQYSHIADKVTKENNELKQKIDKKQQIIVQLESALLQN 1523

Query: 1346 XXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXX---RVNDAEAKV 1402
                 ++    + + + QE+ I +I ++  +L+                  ++ D + + 
Sbjct: 1524 EETLKNVHDRAKEFCKQQEKEINDIKDQYLKLEAEHNAILSQNQEREDENEQMKDQKDQA 1583

Query: 1403 LELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAIL 1462
            L   H LE +  ++ ++  E    LT+ N+E   + +Q+ E +K I  L         I 
Sbjct: 1584 LRQMHTLEDEIGKLKKELQEQHEKLTKSNNERSMLYKQIEEMQKDIAQLGGHNNPSQKIR 1643

Query: 1463 RLKMHENANHYETMQKESEIERV-KLIEELNVKITESVSLNKQVAELNKALEEEVAKTNE 1521
             L   +  N     +K    E++ K IEE N K+ +    N++    N   + + +K + 
Sbjct: 1644 YLNTIKQENSCLKQEKLYLSEQLQKEIEEKN-KLLQQQQQNRK----NTDSDNQSSKLDM 1698

Query: 1522 MQTALENQEIEIVTLNDEITNLQNMVRASSSK 1553
             +  +ENQ      LN+E+T L  ++  S  K
Sbjct: 1699 QKLMVENQR-----LNNEMTKLNQILNLSGVK 1725



 Score =  123 bits (296), Expect = 5e-26
 Identities = 256/1347 (19%), Positives = 573/1347 (42%), Gaps = 125/1347 (9%)

Query: 309  EIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSP 368
            ++ E+    +A   E+ +K  L  H++           + + T+  ES+  SS ++  + 
Sbjct: 163  QLSEEVCTNVAESLEVLQKGSLNRHISSTQMNIESSRSHSVFTIQLESRRQSSQTQVINH 222

Query: 369  LISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVI 428
              SR    + A   +   SQ+  E L +  +  INK+ +  L  VI SL +D     +  
Sbjct: 223  RFSRFHFVDLAGSERQKQSQVQGERLREGCN--INKS-LHILGNVINSLVEDNQSYVHYR 279

Query: 429  SEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLK-- 486
              K T           +  LIA +Q   Q + E  S +      + V   A++ E     
Sbjct: 280  DSKLTFLLKDSLGGNSRTHLIANIQQSQQFYQETLSTLMFSKRVKQVKNKARINEDESGN 339

Query: 487  -QELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTID 545
             + L +EIK +  ++L + + + +++            ++ I  +    L+L+ +     
Sbjct: 340  LESLKNEIKRLK-QELAKSVTTQQQKWESPKKFEQKQQQSFINEQFLQSLELESLMINDQ 398

Query: 546  NFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEM 605
            N+ K+ +  K  +  + E    +    E+E+    ++     +  G+ +E  + K +I++
Sbjct: 399  NYIKLEEILKCYLEQSTESE--TALFLEIEKYLNGIKQLKEGFQLGQQLEQQL-KFVIKL 455

Query: 606  ENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLE 665
            +N            + QK  L Q    +QQ   +++ +LA   Q Q   + +  +++ L+
Sbjct: 456  QNE-----------QIQKLKLNQSADDIQQ---QIQQQLAYALQCQGLVMKTFYENLTLK 501

Query: 666  EQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLE 725
            EQ  A+    K    V  NL L K+ +  T+++  N++     +L           DK +
Sbjct: 502  EQQGAIQTVSKVQVQVDTNLNLLKD-IVETVQNSLNERRQFQQQLDLQFNSQYVTLDKFK 560

Query: 726  KMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESI 785
            ++  E +SE   K+  E+  K+     ++ +I+E +   + I  +L +        ++ +
Sbjct: 561  EL--ETLSEYKEKLLSEQTQKLVF---MEDQIKEIE---KQILQKLEENGITFNENDKVV 612

Query: 786  AVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVV-EKQLLEI 844
             V + +   L+ K   L   LQ   +   E +I  ++++ +L    ++ ++V +KQ +E 
Sbjct: 613  DVRDQQIQDLKTKITDLNQELQNSNQELKELSINSEQVIQQLR--FENQQIVNQKQEIES 670

Query: 845  EHENKELQ-------KKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQ 897
             +E  + Q        K QI+  E Q  Q  L D    Y+   ++ N+    ++E  KY+
Sbjct: 671  NYELTQTQISEFQDNSKQQIINLEQQLSQ--LQDQNSQYSNQYQQLNQ----QNEDLKYK 724

Query: 898  TQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYV 957
              + + E   K++T E    ++Q +++++ L+ +     + AI++ K     YE     +
Sbjct: 725  --IENEEHQNKQLTQE----LIQNQEKLKLLD-QIIVDNDIAIQEFKQQLTSYES---II 774

Query: 958  TQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNAL 1017
             QL+  + +   N++    ++ +L   N  L  +   KQQ +     EQ    ++KL   
Sbjct: 775  IQLKKNINDQNANLQLNQQSISQLELENANL-KQECSKQQNELTLMQEQVSLSMSKLENS 833

Query: 1018 LKQKDEEIIALNQKINNAQVSYMSMVS----DYESKLAQFTTKLENMEEEMQRVSKQLLD 1073
             ++   ++  L+Q+ N    +  S++S    + +S++     +L +  E++Q    QL  
Sbjct: 834  EQELFSQL-QLSQRDNQNLQNENSLLSKANQEMQSEMDVLILELNSKTEDLQNTQIQL-Q 891

Query: 1074 SKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXX 1133
             KQ   E +I++ +Q  QI E    +  ++  I + +        +  +  + +++    
Sbjct: 892  QKQQKYEQEIIIYQQKSQI-ERSTLEKDYQEQIKQQKKDFELLLFQFNTKQSCDLNKLNQ 950

Query: 1134 XXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETL-NTELTGHDVVN 1192
                    +K ++E    + +S  + Q   LN ++Q+   + +QLE+L   +      + 
Sbjct: 951  EILSLNYIIK-EKETNNTESQSQQEFQINLLNQKIQKETQRALQLESLLEGQKNEFQEIQ 1009

Query: 1193 QEQINQLKSKLEQLNT------ENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQR 1246
            +EQ++ +    +QL +      E  +  + V EL  S+ + ++Q+    +EL K+ + Q 
Sbjct: 1010 KEQMSSIDLLQKQLESKQAVIQETSDHYNQVHELYLSLQARMEQKDLVNSEL-KRDILQN 1068

Query: 1247 EADFQKTEHELR-VQLSAFESKYEQLLD----------SVQSSTQEETNKIVTMEQVTSL 1295
            ++  +    E++ +Q      + E L             +Q  TQ+ + K+ T+EQ+T+ 
Sbjct: 1069 KSKLESQTKEIQQLQQKVISIENENLQSRNTMEIQQQGKLQDMTQKLSIKMRTIEQLTAE 1128

Query: 1296 QNKLQDKEEHL-----RN------LQEKYADVINQIEILRSEIE---DEKVAFXXXXXXX 1341
            +  L DK + +     +N      L+++  +  NQ  +L+++I+   +E           
Sbjct: 1129 KINLNDKIKEIECESNKNKQTICLLEQQQHESQNQNNLLQAQIQSLNNELNQKEQEIGFL 1188

Query: 1342 XXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAK 1401
                      L   ++ YK+  +Q  ++ N    QL                 +ND + K
Sbjct: 1189 QQELSKQNQVLDKSSEIYKKETDQMEIDNNILKKQLSDKQKDIHKLEQKLNATLNDLQLK 1248

Query: 1402 V-------LELTH-------QLEL--KDSEIYQKT-HEYTITLTQRNDEFENVRQQLVEY 1444
                    L+L H       QLEL  KD+ + +K   +    +  +++E + +R +L + 
Sbjct: 1249 EQQIDQLKLQLNHLNTNLQQQLELTTKDNLLLKKEIQQLNQHIESQHEEIDQMRIELDQK 1308

Query: 1445 EKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNV-------KITE 1497
            + ++++     +     L L++ + + H +  + + + E  +L+++L++       K   
Sbjct: 1309 QTQVDENKSAVKKLTKQLELEIKQYSLHLKRNEDQHKKEVQELVDQLDIHQKQLQQKDLI 1368

Query: 1498 SVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKH 1557
              SLNKQV  L  A E +    ++ Q  ++  + ++ +  ++ T +   +  ++++++  
Sbjct: 1369 VESLNKQVNGLQCAFETKEDLNHQTQKDIQQLKDKLKSDQNKFTKIIQSLENANNQLKSQ 1428

Query: 1558 VSFASDTKQGRDEQLDNTMNKELLDAV 1584
            +  +S   Q    +  +   +  L ++
Sbjct: 1429 LEESSHQIQENAHKYQSVQKQNDLQSI 1455



 Score = 87.4 bits (207), Expect = 3e-15
 Identities = 147/818 (17%), Positives = 362/818 (44%), Gaps = 51/818 (6%)

Query: 216  QQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLA 275
            Q++ K Q + I +  +  + KQ +++  E+ D   + + E    L+A   +  L +S+L 
Sbjct: 1006 QEIQKEQMSSIDLLQKQLESKQAVIQ--ETSD-HYNQVHELYLSLQARMEQKDLVNSELK 1062

Query: 276  QELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLN 335
            +++ Q              L ++ I     E   ++ + ++EI    +L    ++ + L+
Sbjct: 1063 RDILQNKSKLESQTKEIQQLQQKVISI---ENENLQSRNTMEIQQQGKLQ---DMTQKLS 1116

Query: 336  CQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLN 395
             ++R T ++L  +   +  + K +   S K    I     +   S+ ++   Q   ++LN
Sbjct: 1117 IKMR-TIEQLTAEKINLNDKIKEIECESNKNKQTICLLEQQQHESQNQNNLLQAQIQSLN 1175

Query: 396  QDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLE 455
             + ++K  + EI  L+  +   N+ ++DK   I +K+T           K     Q  + 
Sbjct: 1176 NELNQK--EQEIGFLQQELSKQNQ-VLDKSSEIYKKETDQMEIDNNILKKQLSDKQKDIH 1232

Query: 456  HQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQL 515
              +     +L  +    + ++++      L   L  +++     +L+ K     ++I QL
Sbjct: 1233 KLEQKLNATLNDLQLKEQQIDQLKLQLNHLNTNLQQQLELTTKDNLLLK-----KEIQQL 1287

Query: 516  NDEIDAANKNMIKVKSNHKLKLKQMQKTID-NFSKVSDSNKEIVRLTEELHHLSQKVAEL 574
            N  I++ ++ + +++    ++L Q Q  +D N S V    K++  L  + + L  K  E 
Sbjct: 1288 NQHIESQHEEIDQMR----IELDQKQTQVDENKSAVKKLTKQL-ELEIKQYSLHLKRNE- 1341

Query: 575  EEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENL-AETRLKAISLLESQKFDLVQEL-HI 632
            ++ K  +Q  LVD       + D+++K ++ ++L  E+  K ++ L+   F+  ++L H 
Sbjct: 1342 DQHKKEVQ-ELVD-------QLDIHQKQLQQKDLIVESLNKQVNGLQCA-FETKEDLNHQ 1392

Query: 633  LQQKYDEVEDKLADISQLQSDQVCSEIKSVH--LEEQIDALSASKKELALVIENLKLDKE 690
             Q+   +++DKL    Q +  ++   +++ +  L+ Q++  S   +E A   ++++   +
Sbjct: 1393 TQKDIQQLKDKLKS-DQNKFTKIIQSLENANNQLKSQLEESSHQIQENAHKYQSVQKQND 1451

Query: 691  QLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQ 750
             L     + + +K  ++ +    ++  M    ++ +  +  I++ + K N+E + KI  +
Sbjct: 1452 -LQSIQFNEQQEKYTLLKEQFTRLESQMKQESQIREQYSH-IADKVTKENNELKQKIDKK 1509

Query: 751  FGIDAKIQERDLYIENIESELSKYKSRICRLEES-IAVMEDRRYSLERKADQLGSYLQEK 809
              I  +++   L  E     +       C+ +E  I  ++D+   LE + + + S  QE+
Sbjct: 1510 QQIIVQLESALLQNEETLKNVHDRAKEFCKQQEKEINDIKDQYLKLEAEHNAILSQNQER 1569

Query: 810  QKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISL 869
            +    +   Q+D+ + ++  L D    ++K+L E   +  +   +  +L ++ + +Q  +
Sbjct: 1570 EDENEQMKDQKDQALRQMHTLEDEIGKLKKELQEQHEKLTKSNNERSMLYKQIEEMQKDI 1629

Query: 870  SDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLE 929
            + +  H N   +K    +  + E++  + +   L   L++   E   L+ Q+++  ++ +
Sbjct: 1630 AQLGGHNNP-SQKIRYLNTIKQENSCLKQEKLYLSEQLQKEIEEKNKLLQQQQQNRKNTD 1688

Query: 930  IEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMN-----VEELNKM 984
             + N   +  ++   V N++    +  + Q+   L   KN    +  +     ++ +  +
Sbjct: 1689 SD-NQSSKLDMQKLMVENQRLNNEMTKLNQI-LNLSGVKNRFSTIKGSDGDKIIQSVQLL 1746

Query: 985  NLELID-KHVQKQQTQSPDYTEQYINEINKLNALLKQK 1021
              ELID K   +Q+ +  +        + K   ++KQK
Sbjct: 1747 IQELIDCKQEIQQRNKDQEGKNLKYQTMEKDLLVMKQK 1784



 Score = 48.0 bits (109), Expect = 0.002
 Identities = 78/409 (19%), Positives = 167/409 (40%), Gaps = 38/409 (9%)

Query: 1199 LKSKLEQLNT-ENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHEL 1257
            +K+  E L   E    + TV++++  + + ++    +I E  +  L +R    Q+ + + 
Sbjct: 491  MKTFYENLTLKEQQGAIQTVSKVQVQVDTNLNLLK-DIVETVQNSLNERRQFQQQLDLQF 549

Query: 1258 RVQLSAFES--KYEQLLDSVQSSTQEETNKIVTME-QVTSLQNK-LQDKEEH--LRNLQE 1311
              Q    +   + E L +  +    E+T K+V ME Q+  ++ + LQ  EE+    N  +
Sbjct: 550  NSQYVTLDKFKELETLSEYKEKLLSEQTQKLVFMEDQIKEIEKQILQKLEENGITFNEND 609

Query: 1312 KYADVINQ-IEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQ---EQSI 1367
            K  DV +Q I+ L+++I D                     +L+  NQ  K++    EQ I
Sbjct: 610  KVVDVRDQQIQDLKTKITD------------------LNQELQNSNQELKELSINSEQVI 651

Query: 1368 LNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITL 1427
              +  EN Q+                ++++ +    +    LE + S++  +  +Y+   
Sbjct: 652  QQLRFENQQIVNQKQEIESNYELTQTQISEFQDNSKQQIINLEQQLSQLQDQNSQYSNQY 711

Query: 1428 TQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKL 1487
             Q N + E+++ ++   E + + LT E         ++  E     + +  +++I   + 
Sbjct: 712  QQLNQQNEDLKYKIENEEHQNKQLTQEL--------IQNQEKLKLLDQIIVDNDIAIQEF 763

Query: 1488 IEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMV 1547
             ++L    +  + L K + + N  L+      ++++    N + E     +E+T +Q  V
Sbjct: 764  KQQLTSYESIIIQLKKNINDQNANLQLNQQSISQLELENANLKQECSKQQNELTLMQEQV 823

Query: 1548 RASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDLAMYML 1596
              S SK++          Q       N  N+  L +    E+   M +L
Sbjct: 824  SLSMSKLENSEQELFSQLQLSQRDNQNLQNENSLLSKANQEMQSEMDVL 872


>UniRef50_Q59K46 Cluster: Likely vesicular transport factor Uso1p;
            n=1; Candida albicans|Rep: Likely vesicular transport
            factor Uso1p - Candida albicans (Yeast)
          Length = 1880

 Score =  160 bits (389), Expect = 3e-37
 Identities = 240/1138 (21%), Positives = 481/1138 (42%), Gaps = 106/1138 (9%)

Query: 470  TNTEDVN-EIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIK 528
            T  ED   E+AK+QE  K  LN++   V    L   +K+  ++   ++       +  +K
Sbjct: 774  TKLEDKEQELAKIQEDHKS-LNEKFL-VTANSLCG-IKARTKESETISGPDQQELQEALK 830

Query: 529  VKSNHKLKLKQMQKTIDNFSKVSDSNKE-IVRLTEELHHLSQKVAELE-------EEKGN 580
              +  +  LKQ+++ +D+  +     ++ I  +T +L HL +  +E E        E  N
Sbjct: 831  KGNTSESTLKQLKEKLDSTEQAKKKLEDGINNMTRDLFHLKKSKSEAETQIKQREREFKN 890

Query: 581  LQLHLVDYDSGRMIE-SDVYKKMIEM-ENLAETRLKAISLLESQKFD---LVQELHILQQ 635
            L     +      ++ +++ K   E  + + E   K  SL E  KF+   L ++L   ++
Sbjct: 891  LTYEFENTKKDYELQINNLNKSNNEFKQKINELSKKIESLTEDNKFNAKQLEEKLRDTEE 950

Query: 636  KYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGT 695
              + + DKL   S   +D    + KS   EE + A     + L   I+NL+ + ++    
Sbjct: 951  NNEHLMDKLRSASVAYND--LKKAKSESEEETVKA-KEELETLTSKIDNLEKELKEQQSK 1007

Query: 696  IKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAE---KISELLAKINHEEQSKIQTQFG 752
              +LE   ++I +      +E  D    ++K + E   + SEL+ K+   E+        
Sbjct: 1008 KNELEGQLQNITDSTNEKFKELEDELKSIKKSNKEISSQNSELIQKLEKTEKDLQAKDEE 1067

Query: 753  IDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKA 812
            ID    E    I+N+ SE+S  +S++   EES +  +D   SL           +  +K 
Sbjct: 1068 IDKLKAETKSNIDNLNSEISSLQSKLKEAEESHSSTKDEHSSLS----------ENLKKL 1117

Query: 813  YSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDM 872
              EY   +  ++ +L+  ++  +   K   EIE + K +    +   ++    +   +D+
Sbjct: 1118 KEEYENTKTSMIAKLSAKIEEHK---KATDEIETKTKHITDLQEEHAKQKSQFESERNDI 1174

Query: 873  QQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEI-EDLEIE 931
            + +    +++AN+ +L+++       +    E N K  T E +   ++    I ED    
Sbjct: 1175 KSN----LDEANK-ELSDNREKLSNLEKEKTELNNKLKTQEEKISDLETSVAISEDKSKS 1229

Query: 932  FNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDK 991
                IE   R+K  L    ++N E + + + QLQ   +  + L   +++L +   + I+ 
Sbjct: 1230 LKHDIEDLKREKIKLETTLKENEETMFEKKEQLQVVNDKCKELEACLKKLTETKEKEIND 1289

Query: 992  HVQKQQTQSPDYTEQYINEINKLNALLK----QKDEEIIALNQKINNAQVSYMSMVSDYE 1047
             ++K +    D+      E  KL+ L++    + ++ +I LN++I   +      V D +
Sbjct: 1290 LIRKLEAAKSDHD----TERKKLSLLIEDTKSESEKNVIKLNEQIEKLKGEREKEVRDIQ 1345

Query: 1048 SKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIP 1107
            S+LA  TT  E ++  + +V K+  D ++ N+E    ++++ + +K  KE  L  +    
Sbjct: 1346 SQLAAKTTDWEKIKTTLDKVLKEKSDLEKTNKESVDTLKKEVENLK--KEISLLEDQK-- 1401

Query: 1108 KTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEE--EFIQERSVLQEQSAKLN 1165
            K +          +    +N+D            LK    E  E   E + LQ+ +  L 
Sbjct: 1402 KDDTTKYKELAAQLETKTSNLDSTTMELEKTELELKKVRNELTEATSELTKLQDNNQSLT 1461

Query: 1166 TELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSIS 1225
             E+++    + +  + + E+ G+      Q ++L+  L+ + +E  N  +   +  +S+ 
Sbjct: 1462 EEIEKTKAALTK-SSKDLEVCGN------QKSELQDSLKSVKSELKNFENKYNQETTSLK 1514

Query: 1226 SAVDQRGFEIAELW---KQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEE 1282
              ++++  EI  L    K  +++ E +           +  +  K + L   + S  +  
Sbjct: 1515 DEIEEKQKEIVTLQTELKDRISEVEKERAMLSENSETVIKEYSDKIKSLESKINSIKENH 1574

Query: 1283 TNKIVTM-EQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXX 1341
            + +I T  EQ TSL+  +    +   + Q +  D  NQ++ L++ +E             
Sbjct: 1575 SKEITTHNEQKTSLKQDIAKLSQDHESAQTQLEDKENQLKELKASLEKHNTE-------- 1626

Query: 1342 XXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAK 1401
                      +  +N   K++ E +I ++  E      +             + +D E+K
Sbjct: 1627 ------SATSIEEKNNQIKELSE-TIKSLKTELKTSGDALKQSQKEYKTLKTKNSDTESK 1679

Query: 1402 VLELTHQLELKDSEIYQKTHEYTITLTQRN----DEFENVRQ-------QLVEYEKRIED 1450
            + +   +LE   S++ Q   E    +T+R      E E V+        +L    K ++ 
Sbjct: 1680 LEKQLEELEKVKSDL-QTADEKLKGITEREIALKSELETVKNSGLSTTSELAALTKTVKS 1738

Query: 1451 LTYEKESELAILRLKMHENANHYETMQKESEI-ERVK-LIEELNVKITESVSLNKQVAEL 1508
            L  EKE EL  L     +    Y  +QK S+I E++K L +EL  K  +     K++ EL
Sbjct: 1739 LEKEKE-ELQFLSGNKSKELEDY--IQKHSDISEKLKALTDELKEKTKQFDDSKKKLTEL 1795

Query: 1509 N-------KALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVS 1559
                    K LE E  +T++ +   E ++ EIV LN E+  L+N    +  ++ + VS
Sbjct: 1796 ENDLTSTKKELETEKTQTSKFKNLEERKDKEIVKLNKELELLKNDNSGAKKELSEKVS 1853



 Score =  141 bits (342), Expect = 1e-31
 Identities = 250/1208 (20%), Positives = 517/1208 (42%), Gaps = 114/1208 (9%)

Query: 168  METTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIA 227
            ++T +L+L +++  + +  E+ +K                    ED +Q++ K+QE+  +
Sbjct: 733  LDTKVLNLTKELQTEKENAESNDKELNEKIEKLTNLSTKLETKLEDKEQELAKIQEDHKS 792

Query: 228  MEAEWKDEKQRLLK-DIESKDVRISSLEEANKLLEAARFEISLEHS--KLAQELEQXXXX 284
            +  ++      L      +K+    S  +  +L EA +   + E +  +L ++L+     
Sbjct: 793  LNEKFLVTANSLCGIKARTKESETISGPDQQELQEALKKGNTSESTLKQLKEKLDSTEQA 852

Query: 285  XXXXXXXXXXLAKQSI---EPSCEEKTEIEEKGSLEIANMT---ELTKKIELLEHLNCQI 338
                      + +      +   E +T+I+++   E  N+T   E TKK   L+  N  +
Sbjct: 853  KKKLEDGINNMTRDLFHLKKSKSEAETQIKQR-EREFKNLTYEFENTKKDYELQINN--L 909

Query: 339  RQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDT 398
             ++N E + K+  +  + ++++  +K  +  +  K  R+T    +    +L S ++  + 
Sbjct: 910  NKSNNEFKQKINELSKKIESLTEDNKFNAKQLEEKL-RDTEENNEHLMDKLRSASVAYND 968

Query: 399  DKKI---NKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLE 455
             KK    ++ E  K +  +++L   + + E  + E+ +           K+ L  QLQ  
Sbjct: 969  LKKAKSESEEETVKAKEELETLTSKIDNLEKELKEQQSK----------KNELEGQLQN- 1017

Query: 456  HQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQL 515
                      I   TN E   E+    + +K+  N EI   N  +LI+KL+  E+ +   
Sbjct: 1018 ----------ITDSTN-EKFKELEDELKSIKKS-NKEISSQN-SELIQKLEKTEKDLQAK 1064

Query: 516  NDEIDAANKNMIKVKSNHKLKLKQMQKTIDNF-SKVSDSNKEIVRLTEELHHLSQKVAEL 574
            ++EID       K+K+  K  +  +   I +  SK+ ++ +      +E   LS+ + +L
Sbjct: 1065 DEEID-------KLKAETKSNIDNLNSEISSLQSKLKEAEESHSSTKDEHSSLSENLKKL 1117

Query: 575  EEEKGNLQLHLVDYDSGRMIE-----SDVYKKMIEMENLAETRLKAISLLESQKFDLVQE 629
            +EE  N +  ++   S ++ E      ++  K   + +L E   K  S  ES++ D+   
Sbjct: 1118 KEEYENTKTSMIAKLSAKIEEHKKATDEIETKTKHITDLQEEHAKQKSQFESERNDIKSN 1177

Query: 630  LHILQQKYDEVEDKLADI----SQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENL 685
            L    ++  +  +KL+++    ++L +     E K   LE  +       K L   IE+L
Sbjct: 1178 LDEANKELSDNREKLSNLEKEKTELNNKLKTQEEKISDLETSVAISEDKSKSLKHDIEDL 1237

Query: 686  KLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQS 745
            K +K +L  T+K+ E    +   +LQ    +  +L   L+K++  K  E+   I   E +
Sbjct: 1238 KREKIKLETTLKENEETMFEKKEQLQVVNDKCKELEACLKKLTETKEKEINDLIRKLEAA 1297

Query: 746  KIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSY 805
            K       D + ++  L IE+ +SE  K    + +L E I  ++  R   E++   + S 
Sbjct: 1298 KSDH----DTERKKLSLLIEDTKSESEK---NVIKLNEQIEKLKGER---EKEVRDIQSQ 1347

Query: 806  LQEKQKAYSEYTIQEDELVNRLAVLMDHDRV-VEKQLLEIEHENKEL-----QKKNQILL 859
            L  K   + +     D+++   + L   ++  V+    E+E+  KE+     QKK+    
Sbjct: 1348 LAAKTTDWEKIKTTLDKVLKEKSDLEKTNKESVDTLKKEVENLKKEISLLEDQKKDDTT- 1406

Query: 860  EENQNLQISLSDMQQHYNALVEKANRTDL----AESESTKYQTQLRDLESNLKRITHEHQ 915
             + + L   L     + ++   +  +T+L      +E T+  ++L  L+ N + +T E +
Sbjct: 1407 -KYKELAAQLETKTSNLDSTTMELEKTELELKKVRNELTEATSELTKLQDNNQSLTEEIE 1465

Query: 916  TLIVQKKKEIEDLEIEFN--TQIESAIRDKKVLNEKYE-KNIEYVTQLEAQLQEYKNNIE 972
                   K  +DLE+  N  ++++ +++  K   + +E K  +  T L+ +++E +  I 
Sbjct: 1466 KTKAALTKSSKDLEVCGNQKSELQDSLKSVKSELKNFENKYNQETTSLKDEIEEKQKEIV 1525

Query: 973  NLNMNVEE-LNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQK 1031
             L   +++ ++++  E      +  +T   +Y+++  +  +K+N++ +   +EI   N++
Sbjct: 1526 TLQTELKDRISEVEKERAMLS-ENSETVIKEYSDKIKSLESKINSIKENHSKEITTHNEQ 1584

Query: 1032 INNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQ 1091
              + +     +  D+ES   Q   K   ++E    + K   +S    EE    ++E  + 
Sbjct: 1585 KTSLKQDIAKLSQDHESAQTQLEDKENQLKELKASLEKHNTESATSIEEKNNQIKELSET 1644

Query: 1092 IKELKETKLTFEMNIPKTEG-MIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEF 1150
            IK LK T+L       KT G  +  S  E  +    N D             KV+ + + 
Sbjct: 1645 IKSLK-TEL-------KTSGDALKQSQKEYKTLKTKNSDTESKLEKQLEELEKVKSDLQT 1696

Query: 1151 IQER-SVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTE 1209
              E+   + E+   L +EL+    K   L T  +EL        + + + K +L+ L+  
Sbjct: 1697 ADEKLKGITEREIALKSELET--VKNSGLST-TSELAAL-TKTVKSLEKEKEELQFLSGN 1752

Query: 1210 NDNLLSTVAELRSSISSAVDQRGFEIAELWKQ------HLAQREADFQKTEHELRVQLSA 1263
                L    +  S IS  +     E+ E  KQ       L + E D   T+ EL  + + 
Sbjct: 1753 KSKELEDYIQKHSDISEKLKALTDELKEKTKQFDDSKKKLTELENDLTSTKKELETEKTQ 1812

Query: 1264 FESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEIL 1323
              SK++ L        + +  +IV + +   L+    D     + L EK + + ++IEIL
Sbjct: 1813 -TSKFKNL-------EERKDKEIVKLNK--ELELLKNDNSGAKKELSEKVSKLESEIEIL 1862

Query: 1324 RSEIEDEK 1331
              ++ED+K
Sbjct: 1863 SKKLEDKK 1870



 Score =  129 bits (312), Expect = 5e-28
 Identities = 183/979 (18%), Positives = 413/979 (42%), Gaps = 78/979 (7%)

Query: 632  ILQQKYDEVEDKLADIS-QLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKE 690
            I  + ++E++ K+ +++ +LQ+++  +E     L E+I+ L+    +L   +E+ + +  
Sbjct: 725  ISYELFEELDTKVLNLTKELQTEKENAESNDKELNEKIEKLTNLSTKLETKLEDKEQELA 784

Query: 691  QLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQ 750
            ++    K L N+K  +       I+     ++ +     +++ E L K N  E +  Q +
Sbjct: 785  KIQEDHKSL-NEKFLVTANSLCGIKARTKESETISGPDQQELQEALKKGNTSESTLKQLK 843

Query: 751  FGIDAKIQERDLY---IENIESELSKYKSRICRLEESIAVME----DRRYSLERKADQLG 803
              +D+  Q +      I N+  +L   K      E  I   E    +  Y  E       
Sbjct: 844  EKLDSTEQAKKKLEDGINNMTRDLFHLKKSKSEAETQIKQREREFKNLTYEFENTKKDYE 903

Query: 804  SYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQ 863
              +    K+ +E+  + +EL  ++  L + ++   KQL   E + ++ ++ N+ L+++ +
Sbjct: 904  LQINNLNKSNNEFKQKINELSKKIESLTEDNKFNAKQL---EEKLRDTEENNEHLMDKLR 960

Query: 864  NLQISLSDMQQHYNALVEKA-----------NRTDLAESESTKYQTQLRDLESNLKRITH 912
            +  ++ +D+++  +   E+            ++ D  E E  + Q++  +LE  L+ IT 
Sbjct: 961  SASVAYNDLKKAKSESEEETVKAKEELETLTSKIDNLEKELKEQQSKKNELEGQLQNITD 1020

Query: 913  EHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQ-EYKNNI 971
                   + + E++ ++ + N +I S   +     EK EK+++   +   +L+ E K+NI
Sbjct: 1021 STNEKFKELEDELKSIK-KSNKEISSQNSELIQKLEKTEKDLQAKDEEIDKLKAETKSNI 1079

Query: 972  ENLNMNVEELNKMNLELIDKHVQKQQTQSP------DYTEQYINEINKLNALLKQKDEEI 1025
            +NLN  +  L     E  + H   +   S          E+Y N    + A L  K EE 
Sbjct: 1080 DNLNSEISSLQSKLKEAEESHSSTKDEHSSLSENLKKLKEEYENTKTSMIAKLSAKIEEH 1139

Query: 1026 IALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILV 1085
                 +I         +  ++  + +QF ++  +++  +   +K+L D+++    L+   
Sbjct: 1140 KKATDEIETKTKHITDLQEEHAKQKSQFESERNDIKSNLDEANKELSDNREKLSNLEKEK 1199

Query: 1086 REQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQ 1145
             E ++++K  +E     E ++  +E    S +++      ++++            LK  
Sbjct: 1200 TELNNKLKTQEEKISDLETSVAISEDK--SKSLK------HDIEDLKREKIKLETTLKEN 1251

Query: 1146 EEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQ 1205
            EE  F +++  LQ  + K   EL+ C  K+ + +             +++IN L  KLE 
Sbjct: 1252 EETMF-EKKEQLQVVNDKCK-ELEACLKKLTETK-------------EKEINDLIRKLEA 1296

Query: 1206 LNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFE 1265
              +++D     ++ L     S  ++   ++ E  ++   +RE + +  + +L  + + +E
Sbjct: 1297 AKSDHDTERKKLSLLIEDTKSESEKNVIKLNEQIEKLKGEREKEVRDIQSQLAAKTTDWE 1356

Query: 1266 SKYEQLLDSV--QSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEIL 1323
             K +  LD V  + S  E+TNK    E V +L+ ++++ ++ +  L+++  D   + + L
Sbjct: 1357 -KIKTTLDKVLKEKSDLEKTNK----ESVDTLKKEVENLKKEISLLEDQKKDDTTKYKEL 1411

Query: 1324 RSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXX 1383
             +++E +                    +L+       +   + +  + + N  L +    
Sbjct: 1412 AAQLETK----TSNLDSTTMELEKTELELKKVRNELTEATSE-LTKLQDNNQSLTEEIEK 1466

Query: 1384 XXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVE 1443
                       +     +  EL   L+   SE+    ++Y    T   DE E  ++++V 
Sbjct: 1467 TKAALTKSSKDLEVCGNQKSELQDSLKSVKSELKNFENKYNQETTSLKDEIEEKQKEIVT 1526

Query: 1444 YEKRIEDLTYEKESELAILRLKMHENANHYETMQK--ESEIERVK--LIEELNVKITESV 1499
             +  ++D   E E E A+L          Y    K  ES+I  +K    +E+     +  
Sbjct: 1527 LQTELKDRISEVEKERAMLSENSETVIKEYSDKIKSLESKINSIKENHSKEITTHNEQKT 1586

Query: 1500 SLNKQVAELNK-------ALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSS 1552
            SL + +A+L++        LE++  +  E++ +LE    E  T  +E  N    +  +  
Sbjct: 1587 SLKQDIAKLSQDHESAQTQLEDKENQLKELKASLEKHNTESATSIEEKNNQIKELSETIK 1646

Query: 1553 KIQKHVSFASDT-KQGRDE 1570
             ++  +  + D  KQ + E
Sbjct: 1647 SLKTELKTSGDALKQSQKE 1665



 Score =  111 bits (268), Expect = 1e-22
 Identities = 181/907 (19%), Positives = 394/907 (43%), Gaps = 89/907 (9%)

Query: 720  LTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRIC 779
            LTD    +  +    +   + H+  S+ + +   +   +E D  + N+  EL   K    
Sbjct: 694  LTDVYVNLVKDNFLRIKRALFHDPSSEPRGKISYEL-FEELDTKVLNLTKELQTEKENA- 751

Query: 780  RLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEK 839
              E +   + ++   L   + +L + L++K++  ++  IQED        L +   V   
Sbjct: 752  --ESNDKELNEKIEKLTNLSTKLETKLEDKEQELAK--IQEDH-----KSLNEKFLVTAN 802

Query: 840  QLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQ 899
             L  I+   KE +    I   + Q LQ +L       + L +   + D  E    K +  
Sbjct: 803  SLCGIKARTKESET---ISGPDQQELQEALKKGNTSESTLKQLKEKLDSTEQAKKKLEDG 859

Query: 900  LRDLESNL---KRITHEHQTLIVQKKKEIEDLEIEF-NTQ--IESAIRDKKVLNEKYEKN 953
            + ++  +L   K+   E +T I Q+++E ++L  EF NT+   E  I +    N ++++ 
Sbjct: 860  INNMTRDLFHLKKSKSEAETQIKQREREFKNLTYEFENTKKDYELQINNLNKSNNEFKQK 919

Query: 954  I-EYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDK---------HVQKQQTQSPDY 1003
            I E   ++E+  ++ K N + L   + +  + N  L+DK          ++K +++S + 
Sbjct: 920  INELSKKIESLTEDNKFNAKQLEEKLRDTEENNEHLMDKLRSASVAYNDLKKAKSESEEE 979

Query: 1004 TEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEE 1063
            T +   E+  L + +   ++E+     K N  +    ++      K  +   +L+++++ 
Sbjct: 980  TVKAKEELETLTSKIDNLEKELKEQQSKKNELEGQLQNITDSTNEKFKELEDELKSIKKS 1039

Query: 1064 MQRVSKQLLDSKQHNEELQILVREQDDQIKELK-ETKLTFEMNIPKTEGMIISSTIEPMS 1122
             + +S Q  +  Q  E+ +  ++ +D++I +LK ETK   + N+       ISS    + 
Sbjct: 1040 NKEISSQNSELIQKLEKTEKDLQAKDEEIDKLKAETKSNID-NLNSE----ISSLQSKLK 1094

Query: 1123 DDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQ---ECYTKIIQLE 1179
            +   +              LK  +EE    + S++ + SAK+    +   E  TK   + 
Sbjct: 1095 EAEESHSSTKDEHSSLSENLKKLKEEYENTKTSMIAKLSAKIEEHKKATDEIETKTKHIT 1154

Query: 1180 TLNTELTGHDVVNQEQINQLKSKLEQLNTE---NDNLLSTVAELRSSISSAVDQRGFEIA 1236
             L  E        + + N +KS L++ N E   N   LS + + ++ +++ +  +  +I+
Sbjct: 1155 DLQEEHAKQKSQFESERNDIKSNLDEANKELSDNREKLSNLEKEKTELNNKLKTQEEKIS 1214

Query: 1237 ELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQ 1296
            +L +  +A  E   +  +H++       + K E++         EET      EQ+  + 
Sbjct: 1215 DL-ETSVAISEDKSKSLKHDIE------DLKREKIKLETTLKENEET-MFEKKEQLQVVN 1266

Query: 1297 NKLQDKEEHLRNLQE----KYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDL 1352
            +K ++ E  L+ L E    +  D+I ++E  +S+ + E+                   D 
Sbjct: 1267 DKCKELEACLKKLTETKEKEINDLIRKLEAAKSDHDTERKKLSLLIE-----------DT 1315

Query: 1353 RTENQSYKQMQEQSILNINEENAQLK-KSSXXXXXXXXXXXXRVNDAEAKVLELTHQLEL 1411
            ++E+       E++++ +NE+  +LK +              +  D E   ++ T    L
Sbjct: 1316 KSES-------EKNVIKLNEQIEKLKGEREKEVRDIQSQLAAKTTDWEK--IKTTLDKVL 1366

Query: 1412 KDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENAN 1471
            K+    +KT++ ++   ++  E EN+++++   E + +D T  K  ELA        N +
Sbjct: 1367 KEKSDLEKTNKESVDTLKK--EVENLKKEISLLEDQKKDDT-TKYKELAAQLETKTSNLD 1423

Query: 1472 HYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEI 1531
                  +++E+E  K+  EL    TE+ S   ++ + N++L EE+ KT    T   ++++
Sbjct: 1424 STTMELEKTELELKKVRNEL----TEATSELTKLQDNNQSLTEEIEKTKAALTK-SSKDL 1478

Query: 1532 EIV-----TLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPR 1586
            E+       L D + ++++ ++   +K  +  +   D  + + +++  T+  EL D +  
Sbjct: 1479 EVCGNQKSELQDSLKSVKSELKNFENKYNQETTSLKDEIEEKQKEI-VTLQTELKDRISE 1537

Query: 1587 AELDLAM 1593
             E + AM
Sbjct: 1538 VEKERAM 1544



 Score =  102 bits (244), Expect = 9e-20
 Identities = 208/926 (22%), Positives = 389/926 (42%), Gaps = 74/926 (7%)

Query: 67   VSKRIKEHRKATAELLGRPFVPGISESLANTLKQKEILMEKIKQY-KELSKRSSTTIVRX 125
            + K +KE +    EL G+  +  I++S     K+ E  ++ IK+  KE+S ++S  I + 
Sbjct: 997  LEKELKEQQSKKNELEGQ--LQNITDSTNEKFKELEDELKSIKKSNKEISSQNSELIQKL 1054

Query: 126  XXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNALSVLQVKMKIME---TTILDLQEKINEK 182
                                  SN I   ++ +S LQ K+K  E   ++  D    ++E 
Sbjct: 1055 EKTEKDLQAKDEEIDKLKAETKSN-IDNLNSEISSLQSKLKEAEESHSSTKDEHSSLSEN 1113

Query: 183  DQII--EAKNKATTXXXXXXXXXXXXXXXXXE-DTK-QQMTKMQENFIAMEAEWKDEKQR 238
             + +  E +N  T+                 E +TK + +T +QE     +++++ E+  
Sbjct: 1114 LKKLKEEYENTKTSMIAKLSAKIEEHKKATDEIETKTKHITDLQEEHAKQKSQFESERND 1173

Query: 239  LLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQ 298
            +  +++  +  +S   E    LE  + E++ +     +++                L K 
Sbjct: 1174 IKSNLDEANKELSDNREKLSNLEKEKTELNNKLKTQEEKISDLETSVAISEDKSKSL-KH 1232

Query: 299  SIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMG-TESK 357
             IE    EK ++E   +L+    T   KK E L+ +N +     KELE  L  +  T+ K
Sbjct: 1233 DIEDLKREKIKLET--TLKENEETMFEKK-EQLQVVNDKC----KELEACLKKLTETKEK 1285

Query: 358  AVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSL 417
             ++   +K   L + KS  +T  K  S    L  +T ++     I  NE  ++E +    
Sbjct: 1286 EINDLIRK---LEAAKSDHDTERKKLS---LLIEDTKSESEKNVIKLNE--QIEKLKGER 1337

Query: 418  NKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNE 477
             K++ D +  ++ K T           K TL     L+ +  +E        TN E V+ 
Sbjct: 1338 EKEVRDIQSQLAAKTTDWEKI------KTTL--DKVLKEKSDLEK-------TNKESVDT 1382

Query: 478  IAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKL 537
            + K  E LK+E++  + +   KD   K K    Q+      +D+    + K +   K   
Sbjct: 1383 LKKEVENLKKEIS--LLEDQKKDDTTKYKELAAQLETKTSNLDSTTMELEKTELELKKVR 1440

Query: 538  KQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESD 597
             ++ +     +K+ D+N+ +    E+      K ++  E  GN +  L   DS + ++S+
Sbjct: 1441 NELTEATSELTKLQDNNQSLTEEIEKTKAALTKSSKDLEVCGNQKSEL--QDSLKSVKSE 1498

Query: 598  VYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCS 657
            + K      N   T LK   + E QK ++V     L+ +  EVE + A +S+  S+ V  
Sbjct: 1499 L-KNFENKYNQETTSLKD-EIEEKQK-EIVTLQTELKDRISEVEKERAMLSE-NSETVIK 1554

Query: 658  EI--KSVHLEEQIDALSAS-KKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYI 714
            E   K   LE +I+++  +  KE+    E     K  L   I  L  D E    +L++  
Sbjct: 1555 EYSDKIKSLESKINSIKENHSKEITTHNEQ----KTSLKQDIAKLSQDHESAQTQLEDKE 1610

Query: 715  QENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKY 774
             +  +L   LEK + E  + +  K N++ +   +T   +  +++     ++  + E   Y
Sbjct: 1611 NQLKELKASLEKHNTESATSIEEK-NNQIKELSETIKSLKTELKTSGDALKQSQKE---Y 1666

Query: 775  KSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTI---QEDELVNRLAVLM 831
            K+   +  ++ + +E +   LE+    L +   EK K  +E  I    E E V    +  
Sbjct: 1667 KTLKTKNSDTESKLEKQLEELEKVKSDLQT-ADEKLKGITEREIALKSELETVKNSGLST 1725

Query: 832  DHD-RVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAE 890
              +   + K +  +E E +ELQ  +    +E ++     SD+ +   AL ++        
Sbjct: 1726 TSELAALTKTVKSLEKEKEELQFLSGNKSKELEDYIQKHSDISEKLKALTDELKEKTKQF 1785

Query: 891  SESTKYQTQLR-DLESNLKRI-THEHQTLIVQKKKEIEDLEI-EFNTQIESAIRD----K 943
             +S K  T+L  DL S  K + T + QT   +  +E +D EI + N ++E    D    K
Sbjct: 1786 DDSKKKLTELENDLTSTKKELETEKTQTSKFKNLEERKDKEIVKLNKELELLKNDNSGAK 1845

Query: 944  KVLNEKYEKNIEYVTQLEAQLQEYKN 969
            K L+EK  K    +  L  +L++ K+
Sbjct: 1846 KELSEKVSKLESEIEILSKKLEDKKS 1871



 Score = 90.6 bits (215), Expect = 3e-16
 Identities = 173/811 (21%), Positives = 337/811 (41%), Gaps = 70/811 (8%)

Query: 50   RQIKFERAQKCLENAALVSKRIKEHRKATAELLGR-PFVPGISESLANTLKQKEILMEKI 108
            +++K E         A +S +I+EH+KAT E+  +   +  + E  A    Q E     I
Sbjct: 1115 KKLKEEYENTKTSMIAKLSAKIEEHKKATDEIETKTKHITDLQEEHAKQKSQFESERNDI 1174

Query: 109  K-QYKELSKRSSTTIVRXX--XXXXXXXXXXXXXQLGDVTHLSNTIKEKDNALSVLQVKM 165
            K    E +K  S    +                 Q   ++ L  ++   ++    L+  +
Sbjct: 1175 KSNLDEANKELSDNREKLSNLEKEKTELNNKLKTQEEKISDLETSVAISEDKSKSLKHDI 1234

Query: 166  KIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENF 225
            + ++   + L+  + E ++ +  K +                    E  ++++  +    
Sbjct: 1235 EDLKREKIKLETTLKENEETMFEKKEQLQVVNDKCKELEACLKKLTETKEKEINDLIRKL 1294

Query: 226  IAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELE-QXXXX 284
             A +++   E+++L   IE  D +  S +   KL E    ++  E  K  ++++ Q    
Sbjct: 1295 EAAKSDHDTERKKLSLLIE--DTKSESEKNVIKLNEQIE-KLKGEREKEVRDIQSQLAAK 1351

Query: 285  XXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKE 344
                      L K   E S  EKT  E   +L+   +  L K+I LLE          KE
Sbjct: 1352 TTDWEKIKTTLDKVLKEKSDLEKTNKESVDTLK-KEVENLKKEISLLEDQKKDDTTKYKE 1410

Query: 345  LENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINK 404
            L  +L T  +   + +   +K    +  K  RN  ++  S  ++L      QD ++ + +
Sbjct: 1411 LAAQLETKTSNLDSTTMELEKTE--LELKKVRNELTEATSELTKL------QDNNQSLTE 1462

Query: 405  NEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPS 464
             EI K +  +   +KDL   E   ++K             K         E++ + E  S
Sbjct: 1463 -EIEKTKAALTKSSKDL---EVCGNQKSELQDSL------KSVKSELKNFENKYNQETTS 1512

Query: 465  LIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANK 524
            L       +++ E  K    L+ EL D I +V  K+     +++E  I + +D+I +   
Sbjct: 1513 L------KDEIEEKQKEIVTLQTELKDRISEVE-KERAMLSENSETVIKEYSDKIKSLES 1565

Query: 525  NMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELH----HLSQKVAELEEEKGN 580
             +  +K NH  ++     T  N  K S   ++I +L+++       L  K  +L+E K +
Sbjct: 1566 KINSIKENHSKEI-----TTHNEQKTS-LKQDIAKLSQDHESAQTQLEDKENQLKELKAS 1619

Query: 581  LQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAI--SLLESQKFDLVQELHILQQKYD 638
            L+ H  +  +    +++  K++ E     +T LK    +L +SQK     E   L+ K  
Sbjct: 1620 LEKHNTESATSIEEKNNQIKELSETIKSLKTELKTSGDALKQSQK-----EYKTLKTKNS 1674

Query: 639  EVEDK----LADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYG 694
            + E K    L ++ +++SD   ++ K   + E+  AL +  + +     +   +   L  
Sbjct: 1675 DTESKLEKQLEELEKVKSDLQTADEKLKGITEREIALKSELETVKNSGLSTTSELAALTK 1734

Query: 695  TIKDLENDKEDIM----NK---LQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKI 747
            T+K LE +KE++     NK   L++YIQ++ D+++KL+ ++     EL  K    + SK 
Sbjct: 1735 TVKSLEKEKEELQFLSGNKSKELEDYIQKHSDISEKLKALT----DELKEKTKQFDDSKK 1790

Query: 748  Q-TQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYL 806
            + T+   D    +++L  E  +++ SK+K+   R ++ I  +      L+         L
Sbjct: 1791 KLTELENDLTSTKKEL--ETEKTQTSKFKNLEERKDKEIVKLNKELELLKNDNSGAKKEL 1848

Query: 807  QEK-QKAYSEYTIQEDELVNRLAVLMDHDRV 836
             EK  K  SE  I   +L ++ +V+  HD +
Sbjct: 1849 SEKVSKLESEIEILSKKLEDKKSVMKQHDEL 1879


>UniRef50_A0DBC2 Cluster: Chromosome undetermined scaffold_44, whole
            genome shotgun sequence; n=1; Paramecium tetraurelia|Rep:
            Chromosome undetermined scaffold_44, whole genome shotgun
            sequence - Paramecium tetraurelia
          Length = 2045

 Score =  160 bits (388), Expect = 3e-37
 Identities = 269/1279 (21%), Positives = 550/1279 (43%), Gaps = 117/1279 (9%)

Query: 387  SQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKD 446
            +Q+   T NQ+T  +IN       +     LN    D +  +   +            + 
Sbjct: 670  TQIQINTENQET--QINNQVETNTQFTQHELNHQNQDTQITVETGEKRIQTINQQETQE- 726

Query: 447  TLIAQLQLEHQQHMEGPSLIHVGTNT---EDVNEIAKVQEQLKQELNDEIKDVNVKDLIE 503
             +  Q++ E Q      S  +  T T   +++ E A    Q+  + NDEIK    K LI+
Sbjct: 727  -IQVQIETEDQNTQYVTSQENQNTQTIEQQNIIETADQNTQMSFDENDEIK----KQLIQ 781

Query: 504  KLKSAEE-QITQLNDEIDAANKNMIKVKSNHKL-KLKQMQKTIDNFSKVSDSNK-EIVRL 560
            + +  +  + +Q  DE +  N+  I  + N ++ KLK         +++ +  + + +R 
Sbjct: 782  EDQEIQTVECSQDQDESNQKNQAFILEQLNQEIEKLKDQINQQQQAAQMENEKRLDQMRE 841

Query: 561  TEELHHLSQKVAELEEEKGNLQLHL---VDYDSGRMIESDVYKKMIEMENLAETRLKAIS 617
             E LH   Q ++E ++++  L  +L   +D   G          M+ +E+L     + + 
Sbjct: 842  IENLHQQVQFISEQKDQQSQLLNNLLMQIDKQQGEDSSQCNQSNML-IEDLQAQLYEQLV 900

Query: 618  LLESQKFDLVQ-ELHILQQ--KYDEVEDKLADISQLQSD--QVCSEIKSVH--LEEQIDA 670
             +E QK D++  + H+LQ+  +  ++E K+  +     D  Q   E  S++  L++Q + 
Sbjct: 901  RVEDQKKDIITYQDHLLQKDTQNKQIEQKVELLLSQVEDIMQKFQEQMSINQELKQQNNQ 960

Query: 671  LSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAE 730
             +    E     ++L+ D E L   + +L NDK+DI       I EN +L  K +++ ++
Sbjct: 961  QNQIITEFQEKNQSLQNDIEILQSKLSNLSNDKQDI----DQIISENQELKFKNQQILSQ 1016

Query: 731  KISELLAKINHEEQSKIQTQF------GIDAKIQE-RDLYIENIE-SELSKYKSRICRLE 782
             + E   K N  E+ +   ++          KI+E ++L+ E+ E SE ++ +++     
Sbjct: 1017 -VEEFENKFNESEKLQSDYEYLEQIFAQSQIKIKELQNLFAESQELSENTQTENKSQMFN 1075

Query: 783  ESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEY--TIQED--ELVNRLAVLMDHDRVVE 838
            +S ++ E   + L+    +L     E+ +   E   ++QE+  E++ +     D+++ +E
Sbjct: 1076 KSTSMNEQDGFKLKLDQQELQQEEIEQVQNNDELQKSVQEEQNEIIEQRDNTEDNEKQIE 1135

Query: 839  KQLLEIEHENKELQKKNQILLEENQNLQISLSDMQ------QHYNALVEKANRTDLAESE 892
              L      N+   KK  I  + ++ + +S    +      Q  +   E+ N  D  E +
Sbjct: 1136 VDLTSSNITNETEIKKVNITNKSDEFIDLSQKQKEGEIENVQFKSETDEQQNFQDQQEQQ 1195

Query: 893  STKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLE--IEFNTQIESAIRDKKVLNEKY 950
            S     ++ +L++ L   TH+   +I QK +EI+ L+  I+ N Q E  +R+  +L EK 
Sbjct: 1196 SEIDNNKITNLQNTLLNSTHQ---MIEQKIEEIQQLQDLIQKNKQSEQELRE--ILQEKE 1250

Query: 951  EKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINE 1010
             +N      LE QL + K+ +    +  EEL++    L+ K  Q Q+    D+      E
Sbjct: 1251 ARN----QNLELQLDDLKSQLSLNQLKEEELSQQINSLL-KQNQDQEHNLSDFQNSKSQE 1305

Query: 1011 INKLNALLK------QKDEEIIALNQKINNAQVSY-------MSMVSDYESKLAQFTTKL 1057
            IN LN  ++      +  E  +   Q+    Q  Y         +V   E K  Q  T L
Sbjct: 1306 INDLNLQIQNLVEALKNSESQLTKQQQSECLQTGYEEELKQLKDLVQQNEEKNHQHQTAL 1365

Query: 1058 ENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQ-------IKELKETKLTFEMNIPKTE 1110
            +  + E+Q  S +L +S +   +L+  +    ++       IKEL E     ++ I + E
Sbjct: 1366 QEAQLELQTTSLELENSFKKISQLESTIENNQEEKNQLENSIKELSEKDKLLQIQIEQYE 1425

Query: 1111 GMIISST--IEPMSDDANNV--DXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNT 1166
                + T  IE +    N +  +            LK Q+  E  +E  V  +   +   
Sbjct: 1426 KQSQNYTQQIEQLQSTLNQLQNEYQQLTSELNEEQLKNQKIIEINKENEVKVQLIQQDYQ 1485

Query: 1167 ELQECYTKIIQ-----LETLNTELTGHD--VVN-QEQINQLKSKLEQLNTENDNLLSTVA 1218
             + +   K+ Q     ++ LN +L+  +  ++N +++I  L+ ++++LN  ND +     
Sbjct: 1486 HISQTLVKLEQQSSEEIDGLNEQLSQKEKEILNLKQEIQVLQKQVDELNLNNDEIKRNQE 1545

Query: 1219 ELRSSISSAVDQRGFEIAELWKQHLAQREADFQ-----KTEHELRV-QLSAFESKYEQLL 1272
             LR      + Q   E+  L ++   + +++       +++ E  V Q +  E +Y Q+ 
Sbjct: 1546 ILREQ-DGKLKQEKEELQSLLQKEEQENQSNADMIVELESKFEKAVYQRNEMEKEYLQIK 1604

Query: 1273 DSV----QSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYAD---VINQIEILRS 1325
            D +    ++  Q+    I   E+  +L ++++ K+  ++ LQ++  D    I QIEI  +
Sbjct: 1605 DKISHLEKNYIQKNEQYIALYEESNNLNDQVKGKQHQIQILQKQNEDQNAFIKQIEIALT 1664

Query: 1326 EIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXX 1385
            EI                        L   NQ  +  +++ I N+ ++  Q +K+     
Sbjct: 1665 EIYSNLSQESIQSLDVNSLDKIKSNILNNINQIRESFKKE-IENLTQQLKQSQKACQEAK 1723

Query: 1386 XXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYE 1445
                    ++     +  +   Q+  +  +   K +E      Q  ++ + V Q+  + E
Sbjct: 1724 QQLGDYQQKLILCGTEYSKKEQQINQELQQTQTKFNEQVEKANQIFNQLQKVEQKKKDLE 1783

Query: 1446 KRIEDLTYEKESELAILRLKMHENANHYETM-QKESEIERVKLIEELNVKITESVSLNKQ 1504
            K+++D    ++ +L  ++ K  E  N   ++ +K+SEI  ++   +L+ +  +   LN+Q
Sbjct: 1784 KQVQDSDKIRKDQLEEIKSKQSEIENLKNSINKKQSEINTLQT--QLSSQQQDIQKLNEQ 1841

Query: 1505 VAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQ-KHVSFASD 1563
                NK +  +  +  ++   +++ E  I TLN  I N Q +   +  K   K   + + 
Sbjct: 1842 ----NKVIVNKNCEIQQLTKKIQSYEETIETLNQSIINFQFVNETAQQKFDIKEEEYENK 1897

Query: 1564 TKQGRDEQLDNTMNKELLD 1582
             K+ ++    N +NK+L +
Sbjct: 1898 IKEYKEN--INQLNKQLAE 1914



 Score =  136 bits (328), Expect = 6e-30
 Identities = 222/1112 (19%), Positives = 445/1112 (40%), Gaps = 94/1112 (8%)

Query: 212  EDTKQQMTKMQENFIAMEAEWKDEKQRL------LKDIESKDVRISSLEEANKLLEAARF 265
            ED K+ +   Q++ +  + + K  +Q++      ++DI  K     S+ +  K     + 
Sbjct: 903  EDQKKDIITYQDHLLQKDTQNKQIEQKVELLLSQVEDIMQKFQEQMSINQELKQQNNQQN 962

Query: 266  EISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELT 325
            +I  E  +  Q L+                 KQ I+    E  E++ K    ++ + E  
Sbjct: 963  QIITEFQEKNQSLQNDIEILQSKLSNLSN-DKQDIDQIISENQELKFKNQQILSQVEEFE 1021

Query: 326  KKI----------ELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSG 375
             K           E LE +  Q +   KEL+N  A     S+   + +K      S    
Sbjct: 1022 NKFNESEKLQSDYEYLEQIFAQSQIKIKELQNLFAESQELSENTQTENKSQMFNKSTSMN 1081

Query: 376  RNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXX 435
                 K+K    +L  E + Q  +    +  + + +  I     +  D E  I E D   
Sbjct: 1082 EQDGFKLKLDQQELQQEEIEQVQNNDELQKSVQEEQNEIIEQRDNTEDNEKQI-EVDLTS 1140

Query: 436  XXXXXXXXGKDTLIAQLQLEH----QQHMEGP-SLIHVGTNTEDVNEIAKVQEQLKQELN 490
                     K   I     E     Q+  EG    +   + T++       QEQ  +  N
Sbjct: 1141 SNITNETEIKKVNITNKSDEFIDLSQKQKEGEIENVQFKSETDEQQNFQDQQEQQSEIDN 1200

Query: 491  DEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKV 550
            ++I ++    L    +  E++I ++    D   KN    +   ++ L++ +    N    
Sbjct: 1201 NKITNLQNTLLNSTHQMIEQKIEEIQQLQDLIQKNKQSEQELREI-LQEKEARNQNLELQ 1259

Query: 551  SDSNKEIVRLTE-ELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLA 609
             D  K  + L + +   LSQ++  L ++  + + +L D+ + +    ++    ++++NL 
Sbjct: 1260 LDDLKSQLSLNQLKEEELSQQINSLLKQNQDQEHNLSDFQNSK--SQEINDLNLQIQNLV 1317

Query: 610  ETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSD---QVCSEIKSVHLEE 666
            E    + S L  Q     Q+   LQ  Y+E   +L D+ Q   +   Q  + ++   LE 
Sbjct: 1318 EALKNSESQLTKQ-----QQSECLQTGYEEELKQLKDLVQQNEEKNHQHQTALQEAQLEL 1372

Query: 667  QIDAL---SASKK--ELALVIENLKLDKEQLYGTIKDL-ENDK------EDIMNKLQNYI 714
            Q  +L   ++ KK  +L   IEN + +K QL  +IK+L E DK      E    + QNY 
Sbjct: 1373 QTTSLELENSFKKISQLESTIENNQEEKNQLENSIKELSEKDKLLQIQIEQYEKQSQNYT 1432

Query: 715  QENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKY 774
            Q+   L   L ++  E   +L +++N EEQ K Q    I+   +E ++ ++ I+ +    
Sbjct: 1433 QQIEQLQSTLNQLQNE-YQQLTSELN-EEQLKNQKIIEIN---KENEVKVQLIQQDYQHI 1487

Query: 775  KSRICRLE----ESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVL 830
               + +LE    E I  + ++    E++   L   +Q  QK   E  +  DE+     +L
Sbjct: 1488 SQTLVKLEQQSSEEIDGLNEQLSQKEKEILNLKQEIQVLQKQVDELNLNNDEIKRNQEIL 1547

Query: 831  MDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAE 890
             + D        +++ E +ELQ   Q   +ENQ+    + +++  +   V + N      
Sbjct: 1548 REQDG-------KLKQEKEELQSLLQKEEQENQSNADMIVELESKFEKAVYQRN------ 1594

Query: 891  SESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKY 950
             E  K   Q++D  S+L++   +     +   +E  +L    N Q++      ++L ++ 
Sbjct: 1595 -EMEKEYLQIKDKISHLEKNYIQKNEQYIALYEESNNL----NDQVKGKQHQIQILQKQN 1649

Query: 951  EKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINE 1010
            E    ++ Q+E  L E  +N+       E +  +++  +DK             E +  E
Sbjct: 1650 EDQNAFIKQIEIALTEIYSNLSQ-----ESIQSLDVNSLDKIKSNILNNINQIRESFKKE 1704

Query: 1011 INKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQ 1070
            I  L   LKQ  +      Q++ + Q   +   ++Y  K  Q   +L+  + +    ++Q
Sbjct: 1705 IENLTQQLKQSQKACQEAKQQLGDYQQKLILCGTEYSKKEQQINQELQQTQTKF---NEQ 1761

Query: 1071 LLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDX 1130
            +  + Q   +LQ + +++ D  K+++++       I K +   I S    + +  N+++ 
Sbjct: 1762 VEKANQIFNQLQKVEQKKKDLEKQVQDSD-----KIRKDQLEEIKSKQSEIENLKNSINK 1816

Query: 1131 XXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQ----LETLNTELT 1186
                       L  Q+++  IQ+ +   +     N E+Q+   KI      +ETLN  + 
Sbjct: 1817 KQSEINTLQTQLSSQQQD--IQKLNEQNKVIVNKNCEIQQLTKKIQSYEETIETLNQSII 1874

Query: 1187 GHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEI-AELWKQHLAQ 1245
                VN+    +   K E+   +       + +L   ++      G ++  +   Q + +
Sbjct: 1875 NFQFVNETAQQKFDIKEEEYENKIKEYKENINQLNKQLAERQLDEGVQVQIQELSQKIRK 1934

Query: 1246 READFQKTEHELRVQLSAFESKYEQLLDSVQS 1277
            +E    + +HE    L     K++ +  S Q+
Sbjct: 1935 KEEIIVQLQHEKEQILENCNKKFQMISQSQQN 1966



 Score =  128 bits (309), Expect = 1e-27
 Identities = 258/1395 (18%), Positives = 564/1395 (40%), Gaps = 82/1395 (5%)

Query: 216  QQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLA 275
            QQ+  MQ N     A     KQ  +KD+++  + I  L    + +++    I  +     
Sbjct: 260  QQINSMQNNKQKQSALLNIVKQ--IKDLKTNQIDIEDLRNQFQNIQSL---IETQLINFI 314

Query: 276  QELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLN 335
            Q  +Q              L  + ++ S ++   I  +   E  +   +  K ELL  L 
Sbjct: 315  QNQKQQDNQKIEQQEYEDELTDEDMK-SVQQLIRIYNRKQSESGDKDIIQNKQELLPRLL 373

Query: 336  CQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLN 395
              I+    ELE  L    T S   +  S       S ++      +++   +Q S+E   
Sbjct: 374  KYIQHLQNELE-VLREQPTWSYQQNHTS-------SEQNQDVITLELQQQLNQTSNELYK 425

Query: 396  QDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLE 455
               +   +K +I  L + I+ L    ++K     E               +      + +
Sbjct: 426  VQAEFAESKAQIEALNIQIEDLTNQNLEKSAKNDEIQKQLQENQNKGNQDEKAFQNQETQ 485

Query: 456  HQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVN-VKDLIEKLKSAEEQITQ 514
              Q +E  S I    + +D  E+       + ++ND+ +  N ++++I+     E+Q  Q
Sbjct: 486  TVQLIEDESQIKQIEDQQDEKELKINSPPQETQVNDDGQQNNLIQEVIKTDNDDEKQFNQ 545

Query: 515  LNDEIDAA------NKNMIKVKSNHKLKLKQMQKTIDNFSK--VSDSNKEIVRLTEELHH 566
             +  I  A         ++    N K ++ Q+ +T   F++  +S  N++     +    
Sbjct: 546  NDQSIQTAIEQCDQTTQILLETENQKNQISQVVETTTQFTQHEISQENQDTQINVQTDDK 605

Query: 567  LSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDL 626
              Q + E   ++   Q+      +      +      + E   E ++      +    D 
Sbjct: 606  KIQVITEQGTQETQAQIDTDHQTTQYTAAQEDQNTQTQSEIDDEKQINLNDQQQQTNIDQ 665

Query: 627  VQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLK 686
              +   +Q   +  E ++ +  +  +     E+   + + QI   +  K+   +  +  +
Sbjct: 666  SDQNTQIQINTENQETQINNQVETNTQFTQHELNHQNQDTQITVETGEKRIQTINQQETQ 725

Query: 687  LDKEQLYGTIKDLENDKEDIMNKLQNYIQENM-DLTDKLEKMSAEKISELLAKINHEEQS 745
              + Q+    ++ +          Q   Q+N+ +  D+  +MS ++  E+  ++  E+Q 
Sbjct: 726  EIQVQIETEDQNTQYVTSQENQNTQTIEQQNIIETADQNTQMSFDENDEIKKQLIQEDQE 785

Query: 746  --KIQTQFGIDAKIQERDLYI-ENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQL 802
               ++     D   Q+   +I E +  E+ K K +I + +++  +  ++R    R+ + L
Sbjct: 786  IQTVECSQDQDESNQKNQAFILEQLNQEIEKLKDQINQQQQAAQMENEKRLDQMREIENL 845

Query: 803  GSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEEN 862
               +Q      SE   Q+ +L+N L  LM  D+   +   +    N  ++     L E+ 
Sbjct: 846  HQQVQ----FISEQKDQQSQLLNNL--LMQIDKQQGEDSSQCNQSNMLIEDLQAQLYEQL 899

Query: 863  QNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKK 922
              ++    D+  + + L++K  +    E +     +Q+ D+    +     +Q L  Q  
Sbjct: 900  VRVEDQKKDIITYQDHLLQKDTQNKQIEQKVELLLSQVEDIMQKFQEQMSINQELKQQNN 959

Query: 923  KEIEDLEIEFNTQIESAIRDKKVLNEKYEK---NIEYVTQLEAQLQEYKNNIENLNMNVE 979
            ++   +  EF  + +S   D ++L  K      + + + Q+ ++ QE K   + +   VE
Sbjct: 960  QQ-NQIITEFQEKNQSLQNDIEILQSKLSNLSNDKQDIDQIISENQELKFKNQQILSQVE 1018

Query: 980  EL-NKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKIN-NAQV 1037
            E  NK N        + ++ QS DY  +Y+ +I   + +  ++ + + A +Q+++ N Q 
Sbjct: 1019 EFENKFN--------ESEKLQS-DY--EYLEQIFAQSQIKIKELQNLFAESQELSENTQT 1067

Query: 1038 SYMSMVSDYESKL-AQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELK 1096
               S + +  + +  Q   KL+  ++E+Q+   + ++  Q+N+ELQ  V+E+ ++I E +
Sbjct: 1068 ENKSQMFNKSTSMNEQDGFKLKLDQQELQQ---EEIEQVQNNDELQKSVQEEQNEIIEQR 1124

Query: 1097 ETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEE-EFIQERS 1155
            +     E N  + E  + SS I   ++    V+             K +E E E +Q +S
Sbjct: 1125 DNT---EDNEKQIEVDLTSSNITNETE-IKKVNITNKSDEFIDLSQKQKEGEIENVQFKS 1180

Query: 1156 VLQEQSAKLNTELQECYTKIIQLETL-NTELTG-HDVVNQ--EQINQLKSKLEQLNTEND 1211
               EQ    + + Q+      ++  L NT L   H ++ Q  E+I QL+  L Q N +++
Sbjct: 1181 ETDEQQNFQDQQEQQSEIDNNKITNLQNTLLNSTHQMIEQKIEEIQQLQD-LIQKNKQSE 1239

Query: 1212 NLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQL 1271
              L  + + + + +  ++    ++ +L K  L+  +   ++   ++   L   + +   L
Sbjct: 1240 QELREILQEKEARNQNLE---LQLDDL-KSQLSLNQLKEEELSQQINSLLKQNQDQEHNL 1295

Query: 1272 LDSVQSSTQEETNKIVTMEQ-VTSLQNKLQD--KEEHLRNLQEKYADVINQIEILRSEIE 1328
             D   S +QE  +  + ++  V +L+N      K++    LQ  Y + + Q++ L  + E
Sbjct: 1296 SDFQNSKSQEINDLNLQIQNLVEALKNSESQLTKQQQSECLQTGYEEELKQLKDLVQQNE 1355

Query: 1329 DEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXX 1388
            ++                    +L    +   Q+ E +I N  EE  QL+ S        
Sbjct: 1356 EKNHQHQTALQEAQLELQTTSLELENSFKKISQL-ESTIENNQEEKNQLENSIKELSEKD 1414

Query: 1389 XXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRI 1448
                 ++   E +    T Q+E   S + Q  +EY    ++ N+E +   Q+++E  K  
Sbjct: 1415 KLLQIQIEQYEKQSQNYTQQIEQLQSTLNQLQNEYQQLTSELNEE-QLKNQKIIEINK-- 1471

Query: 1449 EDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAEL 1508
                 E E ++ +++      +     ++++S  E   L E+L+ K  E ++L +++  L
Sbjct: 1472 -----ENEVKVQLIQQDYQHISQTLVKLEQQSSEEIDGLNEQLSQKEKEILNLKQEIQVL 1526

Query: 1509 NKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGR 1568
             K ++E     +E++   E    +   L  E   LQ++++    + Q +     + +   
Sbjct: 1527 QKQVDELNLNNDEIKRNQEILREQDGKLKQEKEELQSLLQKEEQENQSNADMIVELESKF 1586

Query: 1569 DEQL--DNTMNKELL 1581
            ++ +   N M KE L
Sbjct: 1587 EKAVYQRNEMEKEYL 1601



 Score =  128 bits (308), Expect = 2e-27
 Identities = 207/1060 (19%), Positives = 438/1060 (41%), Gaps = 98/1060 (9%)

Query: 306  EKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKK 365
            +  +IE+K  L ++ + ++ +K +    +N +++Q N + +N++ T   E +  +   + 
Sbjct: 922  QNKQIEQKVELLLSQVEDIMQKFQEQMSINQELKQQNNQ-QNQIIT---EFQEKNQSLQN 977

Query: 366  GSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKE 425
               ++  K   +  S  K    Q+ SE        +   +++ + E       K   D E
Sbjct: 978  DIEILQSKL--SNLSNDKQDIDQIISENQELKFKNQQILSQVEEFENKFNESEKLQSDYE 1035

Query: 426  Y---VISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQ 482
            Y   + ++                 L    Q E++  M   S      N +D  ++   Q
Sbjct: 1036 YLEQIFAQSQIKIKELQNLFAESQELSENTQTENKSQMFNKS---TSMNEQDGFKLKLDQ 1092

Query: 483  EQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQK 542
            ++L+QE   EI+ V   D ++K  S +E+  ++ ++ D    N        ++++     
Sbjct: 1093 QELQQE---EIEQVQNNDELQK--SVQEEQNEIIEQRDNTEDN------EKQIEVDLTSS 1141

Query: 543  TIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKM 602
             I N +++   N  I   ++E   LSQK  E E E  N+Q      +     +    +  
Sbjct: 1142 NITNETEIKKVN--ITNKSDEFIDLSQKQKEGEIE--NVQFKSETDEQQNFQDQQEQQSE 1197

Query: 603  IE---MENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCS-E 658
            I+   + NL  T L +   +  QK + +Q+L  L QK  + E +L +I Q +  +  + E
Sbjct: 1198 IDNNKITNLQNTLLNSTHQMIEQKIEEIQQLQDLIQKNKQSEQELREILQEKEARNQNLE 1257

Query: 659  IKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENM 718
            ++   L+ Q+      ++EL+  I +L    +     + D +N K   +N L   IQ  +
Sbjct: 1258 LQLDDLKSQLSLNQLKEEELSQQINSLLKQNQDQEHNLSDFQNSKSQEINDLNLQIQNLV 1317

Query: 719  D-LTDKLEKMSAEKISELLAKINHEE--------QSKIQTQFGIDAKIQERDLYIENIES 769
            + L +   +++ ++ SE L     EE        Q   +        +QE  L ++    
Sbjct: 1318 EALKNSESQLTKQQQSECLQTGYEEELKQLKDLVQQNEEKNHQHQTALQEAQLELQTTSL 1377

Query: 770  ELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAV 829
            EL     +I +LE +I   ++ +  LE    +L    +  Q    +Y  Q      ++  
Sbjct: 1378 ELENSFKKISQLESTIENNQEEKNQLENSIKELSEKDKLLQIQIEQYEKQSQNYTQQIEQ 1437

Query: 830  LMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLA 889
            L      ++ +  ++  E  E Q KNQ ++E N+  ++ +  +QQ Y  + +   + +  
Sbjct: 1438 LQSTLNQLQNEYQQLTSELNEEQLKNQKIIEINKENEVKVQLIQQDYQHISQTLVKLEQQ 1497

Query: 890  ESESTK-YQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNE 948
             SE       QL   E  +  +  E Q L    +K++++L +  N +I+   R++++L E
Sbjct: 1498 SSEEIDGLNEQLSQKEKEILNLKQEIQVL----QKQVDELNLN-NDEIK---RNQEILRE 1549

Query: 949  KYEKNIEYVTQLEAQLQ-EYKNNIENLNMNVE-------------ELNKMNLELIDK--H 992
            +  K  +   +L++ LQ E + N  N +M VE             E+ K  L++ DK  H
Sbjct: 1550 QDGKLKQEKEELQSLLQKEEQENQSNADMIVELESKFEKAVYQRNEMEKEYLQIKDKISH 1609

Query: 993  VQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMV----SDYES 1048
            ++K   Q  +       E N LN  +K K  +I  L QK N  Q +++  +    ++  S
Sbjct: 1610 LEKNYIQKNEQYIALYEESNNLNDQVKGKQHQIQIL-QKQNEDQNAFIKQIEIALTEIYS 1668

Query: 1049 KLAQFTTK--------------LENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKE 1094
             L+Q + +              L N+ +  +   K++ +  Q  ++ Q   +E   Q+ +
Sbjct: 1669 NLSQESIQSLDVNSLDKIKSNILNNINQIRESFKKEIENLTQQLKQSQKACQEAKQQLGD 1728

Query: 1095 LKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQER 1154
             ++  +       K E  I     +  +     V+             KV+++++ ++++
Sbjct: 1729 YQQKLILCGTEYSKKEQQINQELQQTQTKFNEQVEKANQIFNQLQ---KVEQKKKDLEKQ 1785

Query: 1155 SVLQEQSAKLNTELQECYTKIIQLETLNTELTG-HDVVN--QEQINQLKSKLEQLNTEND 1211
              +Q+       +L+E  +K  ++E L   +      +N  Q Q++  +  +++LN +N 
Sbjct: 1786 --VQDSDKIRKDQLEEIKSKQSEIENLKNSINKKQSEINTLQTQLSSQQQDIQKLNEQNK 1843

Query: 1212 NLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQL 1271
             +++   E++        Q   E  E   Q +     +FQ      + +    E +YE  
Sbjct: 1844 VIVNKNCEIQQLTKKI--QSYEETIETLNQSII----NFQFVNETAQQKFDIKEEEYENK 1897

Query: 1272 LDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQE 1311
            +   + +  +   ++   +    +Q ++Q+  + +R  +E
Sbjct: 1898 IKEYKENINQLNKQLAERQLDEGVQVQIQELSQKIRKKEE 1937



 Score =  122 bits (293), Expect = 1e-25
 Identities = 208/1077 (19%), Positives = 458/1077 (42%), Gaps = 95/1077 (8%)

Query: 49   ERQIKFERAQKCLENAALVSKRIKEHRKATAELLGRPFVPGISESLANTLKQKEILMEKI 108
            + QIK +  Q     +  +S+  +   K+  ++  +       +     L Q+E+  E+I
Sbjct: 1043 QSQIKIKELQNLFAESQELSENTQTENKS--QMFNKSTSMNEQDGFKLKLDQQELQQEEI 1100

Query: 109  KQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNALSVLQVKMKIM 168
            +Q +   +   +                   +  +V   S+ I    N   + +V +   
Sbjct: 1101 EQVQNNDELQKSVQEEQNEIIEQRDNTEDNEKQIEVDLTSSNIT---NETEIKKVNITNK 1157

Query: 169  ETTILDLQEKINEKD-QIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIA 227
                +DL +K  E + + ++ K++                    + T  Q T +  N   
Sbjct: 1158 SDEFIDLSQKQKEGEIENVQFKSETDEQQNFQDQQEQQSEIDNNKITNLQNTLL--NSTH 1215

Query: 228  MEAEWKDEKQRLLKDIESKDVRISS-LEEANKLLEAARFEISLEHSKLAQELEQXXXXXX 286
               E K E+ + L+D+  K+ +    L E  +  EA    + L+   L  +L        
Sbjct: 1216 QMIEQKIEEIQQLQDLIQKNKQSEQELREILQEKEARNQNLELQLDDLKSQLSLNQLKEE 1275

Query: 287  XXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIE-LLEHLNCQIRQTNKEL 345
                    L KQ+ +      ++ +   S EI    +L  +I+ L+E L     Q  K+ 
Sbjct: 1276 ELSQQINSLLKQNQDQE-HNLSDFQNSKSQEI---NDLNLQIQNLVEALKNSESQLTKQQ 1331

Query: 346  ENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKN 405
            +++    G E +      K+   L+ +   +N   +     +QL  +T + + +    K 
Sbjct: 1332 QSECLQTGYEEEL-----KQLKDLVQQNEEKNHQHQTALQEAQLELQTTSLELENSFKK- 1385

Query: 406  EIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSL 465
             I++LE  I++  ++    E  I E              KD L+ Q+Q+E  +       
Sbjct: 1386 -ISQLESTIENNQEEKNQLENSIKELSE-----------KDKLL-QIQIEQYEKQSQNYT 1432

Query: 466  IHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKN 525
              +      +N++    +QL  ELN+E   +  + +IE  K  E ++  +  +    ++ 
Sbjct: 1433 QQIEQLQSTLNQLQNEYQQLTSELNEE--QLKNQKIIEINKENEVKVQLIQQDYQHISQT 1490

Query: 526  MIKVKSNHKLKLKQMQKTIDNFSK-VSDSNKEIVRLTEELHHLSQKVAEL----EEEKGN 580
            ++K++       +Q  + ID  ++ +S   KEI+ L +E+  L ++V EL    +E K N
Sbjct: 1491 LVKLE-------QQSSEEIDGLNEQLSQKEKEILNLKQEIQVLQKQVDELNLNNDEIKRN 1543

Query: 581  LQLHLVDYDSGRMIESDVYKKMIEMENLA-ETRLKAISLLESQKFDLVQELHILQQKYDE 639
             ++ L + D     E +  + +++ E    ++    I  LES+    V + + ++++Y +
Sbjct: 1544 QEI-LREQDGKLKQEKEELQSLLQKEEQENQSNADMIVELESKFEKAVYQRNEMEKEYLQ 1602

Query: 640  VEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDL 699
            ++DK   IS L+ + +    + + L E+ + L+   K     I+ L+   E     IK +
Sbjct: 1603 IKDK---ISHLEKNYIQKNEQYIALYEESNNLNDQVKGKQHQIQILQKQNEDQNAFIKQI 1659

Query: 700  ENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQE 759
            E    +I + L     +++D+ + L+K+     S +L  IN   +S  +    +  ++++
Sbjct: 1660 EIALTEIYSNLSQESIQSLDV-NSLDKIK----SNILNNINQIRESFKKEIENLTQQLKQ 1714

Query: 760  RDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQ 819
                 +  + +L  Y+ ++        ++    YS  +K  Q+   LQ+ Q  ++E   +
Sbjct: 1715 SQKACQEAKQQLGDYQQKL--------ILCGTEYS--KKEQQINQELQQTQTKFNEQVEK 1764

Query: 820  EDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNAL 879
             +++ N+L       + VE++  ++E   K++Q  ++I  ++ + ++   S+++   N++
Sbjct: 1765 ANQIFNQL-------QKVEQKKKDLE---KQVQDSDKIRKDQLEEIKSKQSEIENLKNSI 1814

Query: 880  VEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESA 939
             +K +  +  +++ +  Q  ++ L    K I +++   I Q  K+I+  E    T  +S 
Sbjct: 1815 NKKQSEINTLQTQLSSQQQDIQKLNEQNKVIVNKN-CEIQQLTKKIQSYEETIETLNQSI 1873

Query: 940  IRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELN-----KMNLELIDKHVQ 994
            I  + V     +K      + E +++EYK NI  LN  + E       ++ ++ + + ++
Sbjct: 1874 INFQFVNETAQQKFDIKEEEYENKIKEYKENINQLNKQLAERQLDEGVQVQIQELSQKIR 1933

Query: 995  KQQ---TQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDY---ES 1048
            K++    Q     EQ +   NK   ++ Q  + +I   + I  A ++Y    +     +S
Sbjct: 1934 KKEEIIVQLQHEKEQILENCNKKFQMISQSQQNLID-KRIIKEALLNYFDNRAPQKIRQS 1992

Query: 1049 KLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMN 1105
             L Q    L   E+E  ++  Q+   K + +++Q   ++Q+ Q + LK+  L+F +N
Sbjct: 1993 ILQQLCCILTMTEQEAAKIGIQI--QKLNQQDIQ---QKQEQQQQSLKDNLLSFLLN 2044



 Score =  101 bits (241), Expect = 2e-19
 Identities = 231/1219 (18%), Positives = 510/1219 (41%), Gaps = 138/1219 (11%)

Query: 473  EDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSN 532
            + V E+ K+ E LK+E     K     D  +     +EQI +LN E+ +        K  
Sbjct: 192  QKVLELQKIIETLKEEKEYSKKQFQ-GDYNQLEIQFQEQIQRLNQEMVSQRDLFALEKQQ 250

Query: 533  HKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQ-------LHL 585
                + +  + I++          ++ + +++  L     ++E+ +   Q         L
Sbjct: 251  LNRDIDEYIQQINSMQNNKQKQSALLNIVKQIKDLKTNQIDIEDLRNQFQNIQSLIETQL 310

Query: 586  VDYDSGRMIESDVYKKMIEMEN-LAETRLKAISLL---------ESQKFDLVQE------ 629
            +++   +  + +   +  E E+ L +  +K++  L         ES   D++Q       
Sbjct: 311  INFIQNQKQQDNQKIEQQEYEDELTDEDMKSVQQLIRIYNRKQSESGDKDIIQNKQELLP 370

Query: 630  --LHILQQKYDEVED-KLADISQLQSDQVCSE----IKSVHLEEQIDALSASKKELALVI 682
              L  +Q   +E+E  +       Q +   SE    + ++ L++Q++  S    ++    
Sbjct: 371  RLLKYIQHLQNELEVLREQPTWSYQQNHTSSEQNQDVITLELQQQLNQTSNELYKVQAEF 430

Query: 683  ENLKLDKEQLYGTIKDLEN---DKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKI 739
               K   E L   I+DL N   +K    +++Q  +QEN +  ++ EK    + ++ +  I
Sbjct: 431  AESKAQIEALNIQIEDLTNQNLEKSAKNDEIQKQLQENQNKGNQDEKAFQNQETQTVQLI 490

Query: 740  NHEEQSKIQTQFGIDAKIQERDLYIEN--IESELSKYKSRICRLEESIAVMEDRRYSLER 797
              E Q K      I+ +  E++L I +   E++++    +   ++E I    D      +
Sbjct: 491  EDESQIK-----QIEDQQDEKELKINSPPQETQVNDDGQQNNLIQEVIKTDNDDEKQFNQ 545

Query: 798  KADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQ----- 852
                + + +++  +  ++  ++ +   N+++ +++      +   EI  EN++ Q     
Sbjct: 546  NDQSIQTAIEQCDQT-TQILLETENQKNQISQVVETTTQFTQH--EISQENQDTQINVQT 602

Query: 853  --KKNQILLE---ENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRD--LES 905
              KK Q++ E   +    QI        Y A  E  N    +E +  K Q  L D   ++
Sbjct: 603  DDKKIQVITEQGTQETQAQIDTDHQTTQYTAAQEDQNTQTQSEIDDEK-QINLNDQQQQT 661

Query: 906  NLKRITHEHQTLIVQKKKEIE-DLEIEFNTQ-----IESAIRDKKVLNEKYEKNIEYVTQ 959
            N+ +     Q  I  + +E + + ++E NTQ     +    +D ++  E  EK I+ + Q
Sbjct: 662  NIDQSDQNTQIQINTENQETQINNQVETNTQFTQHELNHQNQDTQITVETGEKRIQTINQ 721

Query: 960  -----LEAQLQEYKNNIENL----NMNVEELNKMN-LELIDKHVQKQQTQSPDYTEQYIN 1009
                 ++ Q++    N + +    N N + + + N +E  D++ Q    ++ +  +Q I 
Sbjct: 722  QETQEIQVQIETEDQNTQYVTSQENQNTQTIEQQNIIETADQNTQMSFDENDEIKKQLIQ 781

Query: 1010 EINKLNAL--------LKQKDEEII--ALNQKINNA--QVSYMSMVSDYES-KLAQFTTK 1056
            E  ++  +          QK++  I   LNQ+I     Q++     +  E+ K      +
Sbjct: 782  EDQEIQTVECSQDQDESNQKNQAFILEQLNQEIEKLKDQINQQQQAAQMENEKRLDQMRE 841

Query: 1057 LENMEEEMQRVSKQL-LDSKQHNEELQILVREQDDQIKELKETKLTFE----------MN 1105
            +EN+ +++Q +S+Q    S+  N  L  + ++Q +   +  ++ +  E          + 
Sbjct: 842  IENLHQQVQFISEQKDQQSQLLNNLLMQIDKQQGEDSSQCNQSNMLIEDLQAQLYEQLVR 901

Query: 1106 IPKTEGMIISSTIEPMSDDANN--VDXXXXXXXXXXXXL--KVQEEEEFIQERSVLQEQS 1161
            +   +  II+     +  D  N  ++            +  K QE+    QE      Q 
Sbjct: 902  VEDQKKDIITYQDHLLQKDTQNKQIEQKVELLLSQVEDIMQKFQEQMSINQELKQQNNQQ 961

Query: 1162 AKLNTELQECYTKI-IQLETLNTELTGHDVVNQEQ-INQLKSKLEQLNTENDNLLSTVAE 1219
             ++ TE QE    +   +E L ++L+  ++ N +Q I+Q+ S+ ++L  +N  +LS V E
Sbjct: 962  NQIITEFQEKNQSLQNDIEILQSKLS--NLSNDKQDIDQIISENQELKFKNQQILSQVEE 1019

Query: 1220 LRSSISSAVD-QRGFEIAE--LWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQ 1276
              +  + +   Q  +E  E    +  +  +E      E +   + +  E+K  Q+ +   
Sbjct: 1020 FENKFNESEKLQSDYEYLEQIFAQSQIKIKELQNLFAESQELSENTQTENK-SQMFNKST 1078

Query: 1277 SSTQEETNKIVTMEQVTSLQ--NKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAF 1334
            S  +++  K+   +Q    +   ++Q+ +E  +++QE+  ++I Q +   +E  ++++  
Sbjct: 1079 SMNEQDGFKLKLDQQELQQEEIEQVQNNDELQKSVQEEQNEIIEQRD--NTEDNEKQIEV 1136

Query: 1335 XXXXXXXXXXXXXXXXDLRTENQSY----KQMQEQSILNI--NEENAQLKKSSXXXXXXX 1388
                            ++  ++  +    ++ +E  I N+    E  + +          
Sbjct: 1137 DLTSSNITNETEIKKVNITNKSDEFIDLSQKQKEGEIENVQFKSETDEQQNFQDQQEQQS 1196

Query: 1389 XXXXXRVNDAEAKVLELTHQ-LELKDSEIYQKTHEYTITLTQRNDEFE-NVRQQLVEYEK 1446
                 ++ + +  +L  THQ +E K  EI Q        L Q+N + E  +R+ L E E 
Sbjct: 1197 EIDNNKITNLQNTLLNSTHQMIEQKIEEIQQLQ-----DLIQKNKQSEQELREILQEKEA 1251

Query: 1447 RIEDLTYEKE---SELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNK 1503
            R ++L  + +   S+L++ +LK  E +    ++ K+++ +   L +  N K  E   LN 
Sbjct: 1252 RNQNLELQLDDLKSQLSLNQLKEEELSQQINSLLKQNQDQEHNLSDFQNSKSQEINDLNL 1311

Query: 1504 QVAELNKALEEEVAKTNEMQTALENQEIEIVT-LNDEITNLQNMVRASSSKIQKHVSFAS 1562
            Q+  L +AL     K +E Q   + Q   + T   +E+  L+++V+ +  K  +H +   
Sbjct: 1312 QIQNLVEAL-----KNSESQLTKQQQSECLQTGYEEELKQLKDLVQQNEEKNHQHQTALQ 1366

Query: 1563 DTK---QGRDEQLDNTMNK 1578
            + +   Q    +L+N+  K
Sbjct: 1367 EAQLELQTTSLELENSFKK 1385



 Score = 89.0 bits (211), Expect = 9e-16
 Identities = 191/954 (20%), Positives = 383/954 (40%), Gaps = 100/954 (10%)

Query: 702  DKEDIMNKLQNYIQENMDLTDKLEKMSAE--KISEL----LAKINHEEQSKIQTQFGIDA 755
            D+  I N+ Q  I  N    +KL K+SA+  ++S++    L K N + ++K+ +Q   D 
Sbjct: 135  DQLQISNEFQQIITWNQ-FNEKLNKLSADIKQLSQIKYAPLVKENKQLKAKLSSQ-NQDQ 192

Query: 756  KIQERDLYIENI--ESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAY 813
            K+ E    IE +  E E SK + +    +  I   E  +   +    Q   +  EKQ+  
Sbjct: 193  KVLELQKIIETLKEEKEYSKKQFQGDYNQLEIQFQEQIQRLNQEMVSQRDLFALEKQQLN 252

Query: 814  SEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEEN----QNLQISL 869
             +     DE + ++   M +++  +  LL I  + K+L K NQI +E+     QN+Q  +
Sbjct: 253  RDI----DEYIQQINS-MQNNKQKQSALLNIVKQIKDL-KTNQIDIEDLRNQFQNIQSLI 306

Query: 870  S--------DMQQHYNALVEKANRTDLAESESTKYQTQL------RDLESNLKRITHEHQ 915
                     + +Q  N  +E+    D    E  K   QL      +  ES  K I    Q
Sbjct: 307  ETQLINFIQNQKQQDNQKIEQQEYEDELTDEDMKSVQQLIRIYNRKQSESGDKDIIQNKQ 366

Query: 916  TLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVT---------------QL 960
             L+ +  K I+ L+ E     E      +  +   E+N + +T               ++
Sbjct: 367  ELLPRLLKYIQHLQNELEVLREQPTWSYQQNHTSSEQNQDVITLELQQQLNQTSNELYKV 426

Query: 961  EAQLQEYKNNIENLNMNVEELNKMNLEL------IDKHVQKQQTQ----------SPDYT 1004
            +A+  E K  IE LN+ +E+L   NLE       I K +Q+ Q +              T
Sbjct: 427  QAEFAESKAQIEALNIQIEDLTNQNLEKSAKNDEIQKQLQENQNKGNQDEKAFQNQETQT 486

Query: 1005 EQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEM 1064
             Q I + +++  +  Q+DE+ + +N      QV+        ++ L Q   K +N +E+ 
Sbjct: 487  VQLIEDESQIKQIEDQQDEKELKINSPPQETQVN----DDGQQNNLIQEVIKTDNDDEKQ 542

Query: 1065 QRVSKQLLDS--KQHNEELQILV--REQDDQIKELKETKLTF---EMNIPKTEGMIISST 1117
               + Q + +  +Q ++  QIL+    Q +QI ++ ET   F   E++    +  I   T
Sbjct: 543  FNQNDQSIQTAIEQCDQTTQILLETENQKNQISQVVETTTQFTQHEISQENQDTQINVQT 602

Query: 1118 ----IEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYT 1173
                I+ +++                      +E++  Q +S + ++  ++N   Q+  T
Sbjct: 603  DDKKIQVITEQGTQETQAQIDTDHQTTQYTAAQEDQNTQTQSEIDDEK-QINLNDQQQQT 661

Query: 1174 KIIQLE-----TLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAV 1228
             I Q +      +NTE     + NQ + N   ++  +LN +N +   TV      I +  
Sbjct: 662  NIDQSDQNTQIQINTENQETQINNQVETNTQFTQ-HELNHQNQDTQITVETGEKRIQTIN 720

Query: 1229 DQRGFEI-AELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIV 1287
             Q   EI  ++  +    +    Q+ ++   ++        +Q          E   +++
Sbjct: 721  QQETQEIQVQIETEDQNTQYVTSQENQNTQTIEQQNIIETADQNTQMSFDENDEIKKQLI 780

Query: 1288 TMEQVTSLQNKLQDKEEHLRNLQEKYADVINQ-IEILRSEIEDEKVAFXXXXXXXXXXXX 1346
              +Q        QD++E  +  Q    + +NQ IE L+ +I  ++ A             
Sbjct: 781  QEDQEIQTVECSQDQDESNQKNQAFILEQLNQEIEKLKDQINQQQQA-AQMENEKRLDQM 839

Query: 1347 XXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELT 1406
                +L  + Q   + ++Q    +N    Q+ K               + D +A++ E  
Sbjct: 840  REIENLHQQVQFISEQKDQQSQLLNNLLMQIDKQQGEDSSQCNQSNMLIEDLQAQLYEQL 899

Query: 1407 HQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAI-LRLK 1465
             ++E +  +I      Y   L Q++ + + + Q++     ++ED+  + + +++I   LK
Sbjct: 900  VRVEDQKKDII----TYQDHLLQKDTQNKQIEQKVELLLSQVEDIMQKFQEQMSINQELK 955

Query: 1466 MHENANHY---ETMQKESEIER-VKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNE 1521
               N  +    E  +K   ++  +++++     ++       Q+   N+ L+ +  +   
Sbjct: 956  QQNNQQNQIITEFQEKNQSLQNDIEILQSKLSNLSNDKQDIDQIISENQELKFKNQQILS 1015

Query: 1522 MQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVS-FASDTKQGRDEQLDN 1574
                 EN+  E   L  +   L+ +   S  KI++  + FA   +   + Q +N
Sbjct: 1016 QVEEFENKFNESEKLQSDYEYLEQIFAQSQIKIKELQNLFAESQELSENTQTEN 1069



 Score = 58.8 bits (136), Expect = 1e-06
 Identities = 102/546 (18%), Positives = 222/546 (40%), Gaps = 43/546 (7%)

Query: 1056 KLENMEEEMQRVSKQLLDSKQHN-----EELQILVREQDD-QIKELKETKLTFEMNIPKT 1109
            K++N    ++ V+  LL  KQ +     E+ Q   ++Q D  + EL + ++T EM I + 
Sbjct: 6    KIKNAAGTVKNVTSNLLQEKQTDSDKKQEQTQTQTQKQQDVNLLELDD-QITQEMTIAEL 64

Query: 1110 EGMIISST---IEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNT 1166
                  +    ++   +   N +            ++    ++  Q    L + +  +  
Sbjct: 65   IQKFQQNDCVCLQQQFESWKNQENQYQLLKSKILGIRADFNQQLEQYSQDLWDGAQIVER 124

Query: 1167 ELQECYTKIIQLETLNTELTGHDVVNQ--EQINQLKSKLEQLNT-ENDNLLSTVAELRSS 1223
            +  E   K++    ++ E       NQ  E++N+L + ++QL+  +   L+    +L++ 
Sbjct: 125  QKIEFILKVLDQLQISNEFQQIITWNQFNEKLNKLSADIKQLSQIKYAPLVKENKQLKAK 184

Query: 1224 ISSA-VDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEE 1282
            +SS   DQ+  E+ ++ +    + E ++ K +         F+  Y QL    Q   Q  
Sbjct: 185  LSSQNQDQKVLELQKIIET--LKEEKEYSKKQ---------FQGDYNQLEIQFQEQIQRL 233

Query: 1283 TNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXX 1342
              ++V+   + +L+     K++  R++ E Y   IN ++   ++ +   +          
Sbjct: 234  NQEMVSQRDLFALE-----KQQLNRDIDE-YIQQINSMQ--NNKQKQSALLNIVKQIKDL 285

Query: 1343 XXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKV 1402
                    DLR + Q+ + + E  ++N  +   Q                     +  ++
Sbjct: 286  KTNQIDIEDLRNQFQNIQSLIETQLINFIQNQKQQDNQKIEQQEYEDELTDEDMKSVQQL 345

Query: 1403 LELTH--QLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVE---YEKRIEDLTYEKES 1457
            + + +  Q E  D +I Q   E    L +     +N  + L E   +  +    + E+  
Sbjct: 346  IRIYNRKQSESGDKDIIQNKQELLPRLLKYIQHLQNELEVLREQPTWSYQQNHTSSEQNQ 405

Query: 1458 ELAILRLKMHENANHYETMQKESEIERVKL-IEELNVKITESVSLNKQVA----ELNKAL 1512
            ++  L L+   N    E  + ++E    K  IE LN++I +  + N + +    E+ K L
Sbjct: 406  DVITLELQQQLNQTSNELYKVQAEFAESKAQIEALNIQIEDLTNQNLEKSAKNDEIQKQL 465

Query: 1513 EEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQL 1572
            +E   K N+ + A +NQE + V L ++ + ++ +      K  K  S   +T+   D Q 
Sbjct: 466  QENQNKGNQDEKAFQNQETQTVQLIEDESQIKQIEDQQDEKELKINSPPQETQVNDDGQQ 525

Query: 1573 DNTMNK 1578
            +N + +
Sbjct: 526  NNLIQE 531


>UniRef50_A0DWU7 Cluster: Chromosome undetermined scaffold_67, whole
            genome shotgun sequence; n=3; Paramecium tetraurelia|Rep:
            Chromosome undetermined scaffold_67, whole genome shotgun
            sequence - Paramecium tetraurelia
          Length = 1979

 Score =  159 bits (387), Expect = 4e-37
 Identities = 287/1418 (20%), Positives = 612/1418 (43%), Gaps = 160/1418 (11%)

Query: 217  QMTKMQENFIAMEAEWKDEKQRLLKD---IESKDVRISSLEEANKLLEAARFEISLEHSK 273
            Q+++ Q+     E+E  + KQ++  +   I+    ++  LE  NKLL+    ++ +E  K
Sbjct: 342  QLSQFQDLMAEKESEISNLKQQIDDEHELIQEYQKKVKQLENENKLLKLQLSKM-VESEK 400

Query: 274  LAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIAN--MTELTKKIELL 331
              Q+ +                  +S+     +  + + K  L   N  + +L ++I  L
Sbjct: 401  QLQKQKSEANSEYQHYKDDSSQKLKSLSQEIVDLKQKQNKLGLRDCNQEVEQLNQQISKL 460

Query: 332  EHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRN-----TASKMKSPW 386
            +    +  + N + + K   M ++   +    ++ S    R    N     +    K  +
Sbjct: 461  KSEKEEKERENGQNQIKFQEMKSKYNDLKQSYQELSDQYQRDQQMNKQIVQSLQTQKEDF 520

Query: 387  SQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKD 446
               +SE  +      +++ E+   + +I+ L  DL   ++   +++T             
Sbjct: 521  ENRNSEQQSLFHLDLVSQQELETQQQLIKQLENDLHQAQFAYKQQETKLLDYEDEINNLK 580

Query: 447  TLIAQLQLEHQQHMEGPSLIHVGTNT-EDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKL 505
            T I +L+ EH + +      H+  NT +  ++I +  E   + LND  + +       + 
Sbjct: 581  TQIMRLEEEHTEQL------HILDNTIQSKDQIIQQYESNSRILNDTPEQL-------RS 627

Query: 506  KSAEEQITQ--LNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFS-KVSDSNKEIVRLTE 562
            KS E+   Q  L  +ID+ NK++    SN + +++ + K  + +  ++++ +K + + T+
Sbjct: 628  KSVEQTTIQGHLKSQIDSLNKSL----SNFEQQIRDLTKVNNEYQDQINNKDKILKQKTQ 683

Query: 563  ELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQ 622
            E+  L Q++ +L+     +Q+           +  ++    ++  L +T  K    L  +
Sbjct: 684  EVIQLQQQLKDLQGLNQKIQVQ----------DRAIHHHEKQVSTLNQTIQKLQESLNFK 733

Query: 623  KFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVI 682
               L+ + H ++   ++ +D +    Q Q  Q      S+  E+Q       ++EL   +
Sbjct: 734  DQILLGKQHEIEMLLNQKKDHI----QQQKQQ------SLLFEQQHQKAKFEQQELHNKV 783

Query: 683  ENLKLDKEQLYGTIKDLE--NDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKIN 740
            + L+   EQ+    KD+   N +E+I   LQN IQ+      K ++ S ++  +L  KI 
Sbjct: 784  KQLE---EQIIAKQKDVITINVQEEI---LQNQIQQLEQQMRKHQQDSEDEKKQLNDKIL 837

Query: 741  HEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKAD 800
               Q +++    I   + E+ + ++N ++++S+ +S +   ++ I  +E R   L+++  
Sbjct: 838  RLNQ-ELEEAEKIQISLNEKQVSLDNAQNKVSELESELISSQDQIQQLESRILELQQEIK 896

Query: 801  -QLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILL 859
             +  ++L++ Q+   E   Q  E  N   V M+ D + +K +  +E E ++LQ   Q  L
Sbjct: 897  KERSNFLKDNQQKIEELNSQHQE--NEELVQMNQD-LTQKNMQLLE-EIEQLQS-GQSKL 951

Query: 860  EENQNLQISLSDMQQHYNALVEKANRTDLAESES-----TKYQTQLRDLESNLKRITHEH 914
            + N N +I     +++ N  + K ++  + E  S      + Q   +  ++ L  +  E 
Sbjct: 952  QFNLNQEIQNLRAKENQNKEIIKKHQLQILELNSQISSFNQQQELAKQDKAKLSEMLKEQ 1011

Query: 915  QTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENL 974
               I +  K++E   ++ + QIE      +   E   K  E    +  Q QE +  +  +
Sbjct: 1012 LNTITELNKKLEIENLQNDQQIEE--NKTQFSTELVVKETELCRNVMTQSQETQKLLIQI 1069

Query: 975  NMNVEELNKMNLELIDKHVQKQQTQSPDYTEQY--INEINKLNALLKQKDEEIIALNQKI 1032
               +E+L K  L      +++Q+ Q  D  ++Y  I E +K   L++ + E++ +L Q  
Sbjct: 1070 GTLIEQLEKSKLT-----IKEQEKQLFDQEQKYLIIREESKNQQLIQNQFEKLNSLTQTQ 1124

Query: 1033 NNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDS-KQHNEELQILVREQDDQ 1091
            N    +  + +++   KL       E +E+E  R S+ L+D+  Q     +IL  E   Q
Sbjct: 1125 NLTISNLQNELNEKNLKLQTQVLHAETLEQEF-RNSQVLVDNLNQQLNNFKILNEEYKQQ 1183

Query: 1092 IKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFI 1151
            I+   +   T +  I   E  I          +                 L  QE+E   
Sbjct: 1184 IQSFTQKFQTNQQQIQNLENKI---------KELEQTRLIQESKINETTLLLKQEQENCT 1234

Query: 1152 QERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTEND 1211
            + R+ L E+S +LN ++ E    I Q++  N+              QL S+L++     +
Sbjct: 1235 KLRNDLTEKSNQLNLQVIE----ITQIQNDNSHF-----------KQLNSELQKNLEARE 1279

Query: 1212 NLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYE-Q 1270
             +++   ++ + +   + Q+  E+ E   + L Q + + +K  ++L +QL    +  E Q
Sbjct: 1280 IIIANNIDITNDLDQTIKQKNEELKEKQNKILGQTK-EIEKINNKL-LQLQQQNAMLENQ 1337

Query: 1271 LLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQ-EKYADVINQIEILRSEIED 1329
            + + +Q + Q +       ++V SLQ+   + E++ + LQ +   D  N  ++ +  IE 
Sbjct: 1338 IQERIQINQQIQ-------QEVNSLQHSNHELEQNNKKLQLQIIQDAQNYNQLNQRNIEL 1390

Query: 1330 EKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXX 1389
            ++                   DL+  N+   + Q Q I N NE +    +          
Sbjct: 1391 QE---------RNNTLNNEILDLKKNNKELVENQVQ-ITNKNEADQAQNR-------LIG 1433

Query: 1390 XXXXRVNDAEAKVLELTHQLELKDSEI---YQKTHEYTITLTQRNDEFENVRQQLVEYEK 1446
                ++N+ E K+++L + L++KD +I    Q+       L Q+N++      +L+  +K
Sbjct: 1434 SLQEQINNLEQKIIQLENDLKIKDDQITNSIQENQAQEQKLLQQNNQLSQDHGELMALQK 1493

Query: 1447 RIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVA 1506
               D   ++ ++L   +L+ +      + +Q E + E ++  +++N      + L++Q A
Sbjct: 1494 VDYDKIKQQNNQL---QLQTNSQQQDIQRLQLELQQE-IESKQQIN---NSKIELDQQQA 1546

Query: 1507 ELNKALEEEVAKTNEMQTALENQE----IEIVTLNDEITNLQNMVRASSSKI-------- 1554
             LN+ L ++  +T ++   L++QE     E   LN +I NL + +     ++        
Sbjct: 1547 LLNQKLSQKEQQTQQLDQQLKDQEDLLQKEQNKLNSQIENLNSQISVLRKQLDQLQEIIT 1606

Query: 1555 QKHVSFASDTKQGRDEQ-LDNTMNKELLDAVPRAELDL 1591
            QK V  A  +K+  + Q L    N+E+L    +++LDL
Sbjct: 1607 QKEVELADYSKRESEAQKLFEQKNEEILQL--KSQLDL 1642



 Score =  119 bits (287), Expect = 6e-25
 Identities = 241/1214 (19%), Positives = 511/1214 (42%), Gaps = 112/1214 (9%)

Query: 140  QLGDVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXX 199
            QL D+  L+  I+ +D A+   + ++  +  TI  LQE +N KDQI+  K          
Sbjct: 691  QLKDLQGLNQKIQVQDRAIHHHEKQVSTLNQTIQKLQESLNFKDQILLGKQ--------- 741

Query: 200  XXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKL 259
                        +D  QQ  +    F     + K E+Q L         ++  LEE    
Sbjct: 742  --HEIEMLLNQKKDHIQQQKQQSLLFEQQHQKAKFEQQELHN-------KVKQLEEQIIA 792

Query: 260  LEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIA 319
             +     I+++   L  +++Q                KQ  +       E+EE   ++I+
Sbjct: 793  KQKDVITINVQEEILQNQIQQLEQQMRKHQQDSEDEKKQLNDKILRLNQELEEAEKIQIS 852

Query: 320  NMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTA 379
                L +K   L++   ++     ELE++L +   + + + S   +    I +K   N  
Sbjct: 853  ----LNEKQVSLDNAQNKV----SELESELISSQDQIQQLESRILELQQEI-KKERSNFL 903

Query: 380  SKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXX 439
               +    +L+S+  +Q+ ++ +  N+   L      L +++   +   S+         
Sbjct: 904  KDNQQKIEELNSQ--HQENEELVQMNQ--DLTQKNMQLLEEIEQLQSGQSKLQFNLNQEI 959

Query: 440  XXXXGKDTLIAQLQLEHQ-QHMEGPSLIHVGTNTEDV--NEIAKVQEQLKQELNDEIKDV 496
                 K+    ++  +HQ Q +E  S I      +++   + AK+ E LK++LN  I ++
Sbjct: 960  QNLRAKENQNKEIIKKHQLQILELNSQISSFNQQQELAKQDKAKLSEMLKEQLN-TITEL 1018

Query: 497  NVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKE 556
            N K  IE L+         ND+    NK         +L +K+ +   +  ++  ++ K 
Sbjct: 1019 NKKLEIENLQ---------NDQQIEENKTQFST----ELVVKETELCRNVMTQSQETQKL 1065

Query: 557  IVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAI 616
            ++++   +  L +    ++E+    +  L D +   +I  +  K    ++N  E   K  
Sbjct: 1066 LIQIGTLIEQLEKSKLTIKEQ----EKQLFDQEQKYLIIREESKNQQLIQNQFE---KLN 1118

Query: 617  SLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKK 676
            SL ++Q   +    + L +K  +++ ++     L+ +   S++   +L +Q++      +
Sbjct: 1119 SLTQTQNLTISNLQNELNEKNLKLQTQVLHAETLEQEFRNSQVLVDNLNQQLNNFKILNE 1178

Query: 677  ELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQEN-MDLTDKLEKMSAEKISEL 735
            E    I++     +     I++LEN  +++  +    IQE+ ++ T  L K   E  ++L
Sbjct: 1179 EYKQQIQSFTQKFQTNQQQIQNLENKIKEL--EQTRLIQESKINETTLLLKQEQENCTKL 1236

Query: 736  LAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSK-YKSRICRLEESIAVMEDRRYS 794
               +  E+ +++  Q     +IQ  + + + + SEL K  ++R   +  +I +  D   +
Sbjct: 1237 RNDLT-EKSNQLNLQVIEITQIQNDNSHFKQLNSELQKNLEAREIIIANNIDITNDLDQT 1295

Query: 795  LERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLE-------IEHE 847
            +++K ++    L+EKQ      T + +++ N+L  L   + ++E Q+ E       I+ E
Sbjct: 1296 IKQKNEE----LKEKQNKILGQTKEIEKINNKLLQLQQQNAMLENQIQERIQINQQIQQE 1351

Query: 848  NKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNL 907
               LQ  N  L + N+ LQ+ +    Q+YN L ++    +L E  +T    ++ DL+ N 
Sbjct: 1352 VNSLQHSNHELEQNNKKLQLQIIQDAQNYNQLNQR--NIELQERNNT-LNNEILDLKKNN 1408

Query: 908  KRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEY 967
            K +  E+Q  I   K E +  +   N  I S    ++ +N   +K I+    L+ +  + 
Sbjct: 1409 KELV-ENQVQIT-NKNEADQAQ---NRLIGSL---QEQINNLEQKIIQLENDLKIKDDQI 1460

Query: 968  KNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEI-- 1025
             N+I+      ++L + N +L   H +    Q  DY ++   + N+L      + ++I  
Sbjct: 1461 TNSIQENQAQEQKLLQQNNQLSQDHGELMALQKVDY-DKIKQQNNQLQLQTNSQQQDIQR 1519

Query: 1026 --IALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQI 1083
              + L Q+I + Q    S + + + + A    KL   E++ Q++ +QL   K   + LQ 
Sbjct: 1520 LQLELQQEIESKQQINNSKI-ELDQQQALLNQKLSQKEQQTQQLDQQL---KDQEDLLQK 1575

Query: 1084 LVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLK 1143
               + + QI+ L          + + + +I    +E         +            L+
Sbjct: 1576 EQNKLNSQIENLNSQISVLRKQLDQLQEIITQKEVELADYSKRESEAQKLFEQKNEEILQ 1635

Query: 1144 VQEEEEFIQERS-VLQEQSAKLNTELQECYTKIIQLE-TLNTELTGHDVVNQEQINQLKS 1201
            ++ + + IQ+ +  +Q    +++  + +  ++I +L+  +  + T  D + Q   NQ + 
Sbjct: 1636 LKSQLDLIQQNTKEIQNPQKEIDALIAKKDSEIKELQNVIQAKSTQIDKI-QADSNQNQF 1694

Query: 1202 KLEQLNT--ENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRV 1259
             L+++      DN+L  + + +S       +R F   +  +  +          +  LR 
Sbjct: 1695 LLQEIKALFNQDNILDYLRQFKSQHEKQC-ERKFTYYQCLQSLM----------DELLRN 1743

Query: 1260 QLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQ 1319
            Q +AF   Y Q  + V+ S QE+ N +   + +  ++ KL  K       +EK  D+   
Sbjct: 1744 QQAAF---YAQ--NYVKLSQQEQNNLLAYQKDIQLMKAKLPVKTALSNIKEEKNEDISFS 1798

Query: 1320 IEILRSEIEDEKVA 1333
                ++EI +  V+
Sbjct: 1799 SNGQQAEINENDVS 1812



 Score =  104 bits (249), Expect = 2e-20
 Identities = 212/1122 (18%), Positives = 462/1122 (41%), Gaps = 94/1122 (8%)

Query: 514  QLNDEIDAANKNMIKVK---SNHKLKLKQMQKTIDNFSKVSDSNKEIVR----LTE---E 563
            Q+  +I A   N+++ +    N +   K ++K +           E +R    LTE   E
Sbjct: 76   QIEKKISALKSNLLQSRMSSDNFQFATKPLEKLLKRVDDTGTYKTEQIRADDLLTEILQE 135

Query: 564  LHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQK 623
            L  +S     L+ ++ + +L ++     R I +        +  + +T   +I  L++  
Sbjct: 136  LSFISINAKLLQNQRSSQKLQMLVLKDIREIVAGWNTMQHIINQICQTAQISIYQLQNTN 195

Query: 624  FDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQID-----ALSASKKEL 678
               + +   L + Y  VE       Q   +Q+ S I +       D      ++   ++ 
Sbjct: 196  ISQLFKRDELNKLYSLVEKHQNSYPQ-SFEQLYSIIANSFQSRDQDHNKLIEINTQLRQQ 254

Query: 679  ALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKM--SAEKISELL 736
             +  ++L    + L+  +  LE     + NK Q     N   +++L+      +  SE  
Sbjct: 255  EIQNKDLNTKNKNLFAVVTKLEAKVNKLQNKKQQLELSNKQFSNQLQSSYRPQDTYSEN- 313

Query: 737  AKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLE 796
             K  H+    +++Q  +D+K  ++ L    ++++LS+++  +   E  I+       +L+
Sbjct: 314  DKFKHKNPL-VESQSSLDSKNTQQKL----LDNQLSQFQDLMAEKESEIS-------NLK 361

Query: 797  RKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQ 856
            ++ D     +QE QK   +   +   L  +L+ +++ ++ ++KQ  E    N E Q    
Sbjct: 362  QQIDDEHELIQEYQKKVKQLENENKLLKLQLSKMVESEKQLQKQKSE---ANSEYQHYKD 418

Query: 857  ILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQT 916
               + +Q L+ SLS   Q    L +K N+  L   +  +   QL    S LK    E + 
Sbjct: 419  ---DSSQKLK-SLS---QEIVDLKQKQNKLGL--RDCNQEVEQLNQQISKLKSEKEEKER 469

Query: 917  LIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNM 976
               Q + + ++++ ++N   +S     + L+++Y+++ +   Q+   LQ  K + E  N 
Sbjct: 470  ENGQNQIKFQEMKSKYNDLKQS----YQELSDQYQRDQQMNKQIVQSLQTQKEDFE--NR 523

Query: 977  NVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQ 1036
            N E+ +  +L+L+ +  Q+ +TQ     +Q  N++++     KQ++ +++    +INN +
Sbjct: 524  NSEQQSLFHLDLVSQ--QELETQQ-QLIKQLENDLHQAQFAYKQQETKLLDYEDEINNLK 580

Query: 1037 VSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELK 1096
               M +  ++  +L      +++ ++ +Q+            E+L+    EQ      LK
Sbjct: 581  TQIMRLEEEHTEQLHILDNTIQSKDQIIQQYESNSRILNDTPEQLRSKSVEQTTIQGHLK 640

Query: 1097 ETKLTFEMNIPKTEGMI--ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQER 1154
                +   ++   E  I  ++       D  NN D             K QE  +  Q+ 
Sbjct: 641  SQIDSLNKSLSNFEQQIRDLTKVNNEYQDQINNKDKILKQ--------KTQEVIQLQQQL 692

Query: 1155 SVLQEQSAKLNTELQECYTKIIQLETLNTELTG-HDVVN-QEQINQLKS-KLEQLNTEND 1211
              LQ  + K+  + +  +    Q+ TLN  +    + +N ++QI   K  ++E L  +  
Sbjct: 693  KDLQGLNQKIQVQDRAIHHHEKQVSTLNQTIQKLQESLNFKDQILLGKQHEIEMLLNQKK 752

Query: 1212 NLLSTVAELRSSISSAVDQRGFEIAELWK--QHLAQREADFQKTEHELRVQLSAFESKYE 1269
            + +    +          +  FE  EL    + L ++    QK    + VQ    +++ +
Sbjct: 753  DHIQQQKQQSLLFEQQHQKAKFEQQELHNKVKQLEEQIIAKQKDVITINVQEEILQNQIQ 812

Query: 1270 QLLDSVQSSTQE-ETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIE 1328
            QL   ++   Q+ E  K    +++  L  +L++ E+   +L EK   + N    + SE+E
Sbjct: 813  QLEQQMRKHQQDSEDEKKQLNDKILRLNQELEEAEKIQISLNEKQVSLDNAQNKV-SELE 871

Query: 1329 DEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNIN---EENAQLKKSSXXXX 1385
             E ++                 +++ E  ++ +  +Q I  +N   +EN +L + +    
Sbjct: 872  SELISSQDQIQQLESRILELQQEIKKERSNFLKDNQQKIEELNSQHQENEELVQMNQDLT 931

Query: 1386 XXXXXXXXRVNDAEAKVLELTHQL----------ELKDSEIYQKTHEYTITLTQRNDEFE 1435
                     +   ++   +L   L          E ++ EI +K     + L  +   F 
Sbjct: 932  QKNMQLLEEIEQLQSGQSKLQFNLNQEIQNLRAKENQNKEIIKKHQLQILELNSQISSF- 990

Query: 1436 NVRQQLVEYEK-RIEDLTYEKESELAILRLKMH-ENANHYETMQK-------ESEIERVK 1486
            N +Q+L + +K ++ ++  E+ + +  L  K+  EN  + + +++       E  ++  +
Sbjct: 991  NQQQELAKQDKAKLSEMLKEQLNTITELNKKLEIENLQNDQQIEENKTQFSTELVVKETE 1050

Query: 1487 LIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNM 1546
            L   +  +  E+  L  Q+  L + LE+      E +  L +QE + + + +E  N Q +
Sbjct: 1051 LCRNVMTQSQETQKLLIQIGTLIEQLEKSKLTIKEQEKQLFDQEQKYLIIREESKN-QQL 1109

Query: 1547 VRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAE 1588
            ++    K+       + T      +L N  N +L   V  AE
Sbjct: 1110 IQNQFEKLNSLTQTQNLTISNLQNEL-NEKNLKLQTQVLHAE 1150



 Score = 98.7 bits (235), Expect = 1e-18
 Identities = 165/859 (19%), Positives = 356/859 (41%), Gaps = 69/859 (8%)

Query: 765  ENIESELSKYKSRICRLEESIAVMEDRRYSLER---KADQLGSYLQEKQKAYSEYT--IQ 819
            + IE ++S  KS + +   S    +     LE+   + D  G+Y  E+ +A    T  +Q
Sbjct: 75   QQIEKKISALKSNLLQSRMSSDNFQFATKPLEKLLKRVDDTGTYKTEQIRADDLLTEILQ 134

Query: 820  EDELVNRLAVLMDHDRVVEKQLLEIEHENKEL----QKKNQILLEENQNLQISLSDMQQH 875
            E   ++  A L+ + R  +K  + +  + +E+         I+ +  Q  QIS+  +Q  
Sbjct: 135  ELSFISINAKLLQNQRSSQKLQMLVLKDIREIVAGWNTMQHIINQICQTAQISIYQLQNT 194

Query: 876  YNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQ 935
              + + K +  +   S   K+Q         L  I         Q + +  +  IE NTQ
Sbjct: 195  NISQLFKRDELNKLYSLVEKHQNSYPQSFEQLYSIIANS----FQSRDQDHNKLIEINTQ 250

Query: 936  IESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQK 995
            +       K LN K +     VT+LEA++    N ++N    +E  NK     +    + 
Sbjct: 251  LRQQEIQNKDLNTKNKNLFAVVTKLEAKV----NKLQNKKQQLELSNKQFSNQLQSSYRP 306

Query: 996  QQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVS-YMSMVSDYESKLAQFT 1054
            Q T S +   ++ N + +  + L  K+ +     QK+ + Q+S +  ++++ ES+++   
Sbjct: 307  QDTYSENDKFKHKNPLVESQSSLDSKNTQ-----QKLLDNQLSQFQDLMAEKESEISNLK 361

Query: 1055 TKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMII 1114
             ++++  E +Q   K++   +  N+ L++ + +  +  K+L++ K          +    
Sbjct: 362  QQIDDEHELIQEYQKKVKQLENENKLLKLQLSKMVESEKQLQKQKSEANSEYQHYKDDS- 420

Query: 1115 SSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTK 1174
            S  ++ +S +   VD               QE E+  Q+ S L+ +  +   E  +   K
Sbjct: 421  SQKLKSLSQEI--VDLKQKQNKLGLRDCN-QEVEQLNQQISKLKSEKEEKERENGQNQIK 477

Query: 1175 IIQLETLNTEL--TGHDVVNQEQINQLKSK--LEQLNTENDNLLSTVAELRSSIS-SAVD 1229
              ++++   +L  +  ++ +Q Q +Q  +K  ++ L T+ ++  +  +E +S      V 
Sbjct: 478  FQEMKSKYNDLKQSYQELSDQYQRDQQMNKQIVQSLQTQKEDFENRNSEQQSLFHLDLVS 537

Query: 1230 QRGFEIAE-LWKQ-----HLAQ--------READFQKTEHELRVQLSAFESKYEQLLDSV 1275
            Q+  E  + L KQ     H AQ        +  D++   + L+ Q+   E ++ + L  +
Sbjct: 538  QQELETQQQLIKQLENDLHQAQFAYKQQETKLLDYEDEINNLKTQIMRLEEEHTEQLHIL 597

Query: 1276 QSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFX 1335
             ++ Q +   I   +Q  S    L D  E LR+   +   +   ++     +      F 
Sbjct: 598  DNTIQSKDQII---QQYESNSRILNDTPEQLRSKSVEQTTIQGHLKSQIDSLNKSLSNFE 654

Query: 1336 XXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLK---KSSXXXXXXXXXXX 1392
                            +  +++  KQ + Q ++ + ++   L+   +             
Sbjct: 655  QQIRDLTKVNNEYQDQINNKDKILKQ-KTQEVIQLQQQLKDLQGLNQKIQVQDRAIHHHE 713

Query: 1393 XRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLT 1452
             +V+     + +L   L  KD  +  K HE  + L Q+ D  +  +QQ + +E++ +   
Sbjct: 714  KQVSTLNQTIQKLQESLNFKDQILLGKQHEIEMLLNQKKDHIQQQKQQSLLFEQQHQKAK 773

Query: 1453 YEKE---SELAILRLKMHENANHYETMQKESEI--ERVKLIEELNVK-----ITESVSLN 1502
            +E++   +++  L  ++        T+  + EI   +++ +E+   K       E   LN
Sbjct: 774  FEQQELHNKVKQLEEQIIAKQKDVITINVQEEILQNQIQQLEQQMRKHQQDSEDEKKQLN 833

Query: 1503 KQVAELNKALEEE---VAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVS 1559
             ++  LN+ LEE        NE Q +L+N + ++  L  E+ + Q+ ++   S+I   + 
Sbjct: 834  DKILRLNQELEEAEKIQISLNEKQVSLDNAQNKVSELESELISSQDQIQQLESRI---LE 890

Query: 1560 FASDTKQGRDEQLDNTMNK 1578
               + K+ R   L +   K
Sbjct: 891  LQQEIKKERSNFLKDNQQK 909



 Score = 44.0 bits (99), Expect = 0.035
 Identities = 61/342 (17%), Positives = 142/342 (41%), Gaps = 19/342 (5%)

Query: 1263 AFESKYEQLLDSVQSSTQEETNKIVTMEQVTSL-QNKLQDKEEHLRNLQEKYADVINQIE 1321
            +FE  Y  + +S QS  Q+  NK++ +   T L Q ++Q+K+ + +N +  +A V+ ++E
Sbjct: 222  SFEQLYSIIANSFQSRDQDH-NKLIEIN--TQLRQQEIQNKDLNTKN-KNLFA-VVTKLE 276

Query: 1322 ILRSEIEDEK--VAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQE--QSILNINEENAQL 1377
               ++++++K  +                  D  +EN  +K      +S  +++ +N Q 
Sbjct: 277  AKVNKLQNKKQQLELSNKQFSNQLQSSYRPQDTYSENDKFKHKNPLVESQSSLDSKNTQQ 336

Query: 1378 KKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENV 1437
            K               +    E+++  L  Q++  + E+ Q+  +    L   N   +  
Sbjct: 337  KLLDNQLSQFQDLMAEK----ESEISNLKQQID-DEHELIQEYQKKVKQLENENKLLKLQ 391

Query: 1438 RQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKL-IEELNVKIT 1496
              ++VE EK+++    E  SE    +    +          + + ++ KL + + N ++ 
Sbjct: 392  LSKMVESEKQLQKQKSEANSEYQHYKDDSSQKLKSLSQEIVDLKQKQNKLGLRDCNQEVE 451

Query: 1497 ESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQK 1556
            +   LN+Q+++L    EE+  +  + Q   +  + +   L      L +  +      ++
Sbjct: 452  Q---LNQQISKLKSEKEEKERENGQNQIKFQEMKSKYNDLKQSYQELSDQYQRDQQMNKQ 508

Query: 1557 HVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDLAMYMLHQ 1598
             V      K+  + +     +   LD V + EL+    ++ Q
Sbjct: 509  IVQSLQTQKEDFENRNSEQQSLFHLDLVSQQELETQQQLIKQ 550


>UniRef50_UPI0000F1EC3A Cluster: PREDICTED: hypothetical protein; n=4;
            Danio rerio|Rep: PREDICTED: hypothetical protein - Danio
            rerio
          Length = 2775

 Score =  158 bits (384), Expect = 1e-36
 Identities = 226/1141 (19%), Positives = 486/1141 (42%), Gaps = 81/1141 (7%)

Query: 475  VNEIAKVQEQLKQEL---NDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKV-K 530
            ++ + K +E+L   L   N E++ +  K   E+ K+AE ++    DE++   +   KV +
Sbjct: 916  IDGLLKEKEELLDHLEKRNTELEKLQTKSAAEQ-KAAELRLRGACDEVERWKERENKVQR 974

Query: 531  SNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDS 590
               +L  K +++       +  + +E  ++++ +     ++    E+   L+L L   + 
Sbjct: 975  EKEELNQKFLERVERESQNLEITQREKAKMSDLMKKKEDEIRRRGEDIEELKLKLQSNEK 1034

Query: 591  G-RMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQ 649
                +E ++ +K   +E+  ET  K  + L+ +K D ++E    Q+K DE E +     +
Sbjct: 1035 TIESLEIELQQKET-LESRVETLEKLNTQLKEKKLDKIRENESRQKKRDEQEREKEVRWR 1093

Query: 650  LQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTI----KDLE----- 700
             Q +Q    +  + L+ +ID L   K+ ++L++E  + D EQL  T+    + LE     
Sbjct: 1094 RQLEQKDEGL--IELKSRIDELIGEKEHISLLVEEREKDIEQLQSTLSTEKRALELRLKE 1151

Query: 701  -NDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQE 759
              D  +   +    +++  +  +++ +    ++SELL +   E Q + +    +  +IQ 
Sbjct: 1152 ARDNAEWWKRRAGNMEKVKESVNRVAEREKTELSELLREREEEVQKREEVISDLKNRIQS 1211

Query: 760  RDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQ 819
             ++ IE +E+++ +   ++  L E I+ M++R    +++ D++   L+E++K       +
Sbjct: 1212 LEVIIEKLETDIEQKNEQLELLNEQISQMKEREIEDQKELDRMQENLKEQEKQLKR---E 1268

Query: 820  EDEL-VNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNA 878
             D L +  + V+ + + ++E+    IE  + EL +      +E +  +  L       N 
Sbjct: 1269 LDHLNIKMVGVIQEKEELLER----IEERDGELTELQVKFTQEQRMFEQKLKAEHAEVNR 1324

Query: 879  LVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIES 938
               K     +AE E  +   + RD E   ++   E      +++K+ E+L      Q + 
Sbjct: 1325 CKAK-----IAEMEQDQVNLKERDEEQRKRQKMEER----YREQKQTEEL-----VQKDV 1370

Query: 939  AIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQT 998
             +R  K+  E+  + IE   ++  + QE       L  + EE        + K +Q++  
Sbjct: 1371 EVRQLKLKIEELNQEIEQDRRIRMEQQEDLEQQTALLRDAEE----EARTLKKTLQQKDK 1426

Query: 999  QSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLE 1058
            +  D     ++   K   LLK+K  E    N K+ ++     + +     +L     +L 
Sbjct: 1427 EERD----RLHHEEKEKTLLKEKLHEAEQRNIKVLSSLQEIETTLEKERYQLRGKEERLM 1482

Query: 1059 NMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELK---------ETKLTFEMNIPKT 1109
               EE+  + ++    K+  EEL  L+ EQ  ++K L+         E +L+  +   + 
Sbjct: 1483 ECNEELFLIKRERDQEKESIEELNKLIGEQGKEVKTLRGKLDERLEEEGRLSKLLQNQRV 1542

Query: 1110 EGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQ 1169
            E  ++ S  E + ++   +             L+ Q  +E + ++  L+ +     TE+ 
Sbjct: 1543 EVQVLESRAENIEEEKQQLKRSLSQIEEEKRHLETQLTDEKV-DKERLRVRLEDQATEVT 1601

Query: 1170 ECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVD 1229
            +   KI++ E   ++L  +  V  +         E+        LS +   +S + + + 
Sbjct: 1602 K-LNKILEEERKLSQLLQNSRVEAQMFESRAQNTEEEKQLLKRSLSQIEREKSRLETQLT 1660

Query: 1230 QRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTM 1289
                +  +L K  L  ++ +  K + ++  ++   E K  QLL + +   Q   ++   +
Sbjct: 1661 DEKMDKEKL-KARLEDQDKEVTKLKEKMN-EILEEERKLSQLLQNSRVEAQMLESRAENI 1718

Query: 1290 E-QVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDE--KVAFXXXXXXXXXXXX 1346
            E +   L+  L   EE  R+L  +  D     E LR+ +ED+  +V              
Sbjct: 1719 EVEKQQLKRSLTQIEEEKRHLGTQLTDEKMDKERLRAWVEDQATEVTKLKEKLSEMIEEE 1778

Query: 1347 XXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELT 1406
                 L   ++    + E    NI EE  QL +S             ++ D +     L 
Sbjct: 1779 RKLSQLLQNSRVEAHILESRTENIEEEKQQLTRSLTQIEKEKRHLETQLTDEKMDKERLR 1838

Query: 1407 HQLELKDSEI---YQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILR 1463
             +L+ + +E+    +K +E      + +   +N R +    E R E+ T E++ +L  + 
Sbjct: 1839 ARLKDQATEVTKLKEKLNEMIEEERKLSQLLQNSRVEAQMLESRAEN-TIEEKQQLKRVL 1897

Query: 1464 LKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQ 1523
             ++ E     ET   + +I+R +L   L  + TE   L +   +LNK +E+E     ++ 
Sbjct: 1898 SQVEEEKRLLETQLTDEKIDRERLKARLEDQATEVTKLKE---KLNKMVEDE----RKLS 1950

Query: 1524 TALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQL-DNTMNKELLD 1582
              L+N ++E   L     NL+        ++++ ++   + K+  + QL D  +++E L 
Sbjct: 1951 HLLQNSQVETQMLESRTENLEE----EKQQLKRSLTQIEEEKRCLETQLTDEKIDRERLR 2006

Query: 1583 A 1583
            A
Sbjct: 2007 A 2007



 Score =  156 bits (379), Expect = 4e-36
 Identities = 246/1341 (18%), Positives = 567/1341 (42%), Gaps = 101/1341 (7%)

Query: 212  EDTKQQMTKMQENFIAMEAEWK---DEKQRLLKDIESKDVRISSLEEANKLLEAARFEIS 268
            E T+++  KM +     E E +   ++ + L   ++S +  I SLE   +  E     + 
Sbjct: 995  EITQREKAKMSDLMKKKEDEIRRRGEDIEELKLKLQSNEKTIESLEIELQQKETLESRVE 1054

Query: 269  LEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKI 328
                   Q  E+                +Q  E     + ++E+K    I   + + + I
Sbjct: 1055 TLEKLNTQLKEKKLDKIRENESRQKKRDEQEREKEVRWRRQLEQKDEGLIELKSRIDELI 1114

Query: 329  ELLEHLNCQIRQTNKELENKLATMGTESKAVS---SPSKKGSPLISRKSGRNTASKMKSP 385
               EH++  + +  K++E   +T+ TE +A+      ++  +    R++G     K+K  
Sbjct: 1115 GEKEHISLLVEEREKDIEQLQSTLSTEKRALELRLKEARDNAEWWKRRAG--NMEKVKES 1172

Query: 386  WSQLSSETLNQDTD-KKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXG 444
             ++++     + ++  +  + E+ K E VI  L   +   E +I + +T           
Sbjct: 1173 VNRVAEREKTELSELLREREEEVQKREEVISDLKNRIQSLEVIIEKLETDI--------- 1223

Query: 445  KDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQ---ELNDEIKDVNVKDL 501
             +    QL+L ++Q  +           ED  E+ ++QE LK+   +L  E+  +N+K +
Sbjct: 1224 -EQKNEQLELLNEQISQMKE-----REIEDQKELDRMQENLKEQEKQLKRELDHLNIK-M 1276

Query: 502  IEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLT 561
            +  ++  EE + ++ +E D     +       ++K  Q Q+  +   K   +        
Sbjct: 1277 VGVIQEKEELLERI-EERDGELTEL-------QVKFTQEQRMFEQKLKAEHA-------- 1320

Query: 562  EELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISL--- 618
             E++    K+AE+E+++ NL+    +    + +E + Y++  + E L +  ++   L   
Sbjct: 1321 -EVNRCKAKIAEMEQDQVNLKERDEEQRKRQKME-ERYREQKQTEELVQKDVEVRQLKLK 1378

Query: 619  LESQKFDLVQELHILQQKYDEVEDKLADISQLQSD-QVCSEIKSVHLEEQIDALSASKKE 677
            +E    ++ Q+  I  ++ +++E + A +   + + +   +      +E+ D L   +KE
Sbjct: 1379 IEELNQEIEQDRRIRMEQQEDLEQQTALLRDAEEEARTLKKTLQQKDKEERDRLHHEEKE 1438

Query: 678  LALVIENLKLDKE---QLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISE 734
              L+ E L   ++   ++  +++++E   E    +L+   +  M+  ++L  +  E+  E
Sbjct: 1439 KTLLKEKLHEAEQRNIKVLSSLQEIETTLEKERYQLRGKEERLMECNEELFLIKRERDQE 1498

Query: 735  LLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYS 794
               K + EE +K+  + G + K   R    E +E E  +    +      + V+E R  +
Sbjct: 1499 ---KESIEELNKLIGEQGKEVKTL-RGKLDERLEEE-GRLSKLLQNQRVEVQVLESRAEN 1553

Query: 795  LERKADQLGSYLQ--EKQKAYSEYTIQEDEL-VNRLAVLMDHDRVVEKQLLEIEHENKEL 851
            +E +  QL   L   E++K + E  + ++++   RL V ++       +L +I  E ++L
Sbjct: 1554 IEEEKQQLKRSLSQIEEEKRHLETQLTDEKVDKERLRVRLEDQATEVTKLNKILEEERKL 1613

Query: 852  QKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRIT 911
             +  Q    E Q  +    + ++    L    ++    E E ++ +TQL D + + +++ 
Sbjct: 1614 SQLLQNSRVEAQMFESRAQNTEEEKQLLKRSLSQ---IEREKSRLETQLTDEKMDKEKLK 1670

Query: 912  H--EHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKN 969
               E Q   V K KE  +  +E   ++   +++ +V  +  E   E    +E + Q+ K 
Sbjct: 1671 ARLEDQDKEVTKLKEKMNEILEEERKLSQLLQNSRVEAQMLESRAE---NIEVEKQQLKR 1727

Query: 970  NIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALN 1029
            ++  +    EE   +  +L D+ + K++ ++  + E    E+ KL   L +  EE   L+
Sbjct: 1728 SLTQIE---EEKRHLGTQLTDEKMDKERLRA--WVEDQATEVTKLKEKLSEMIEEERKLS 1782

Query: 1030 QKINNAQVS---YMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVR 1086
            Q + N++V      S   + E +  Q T  L  +E+E + +  QL D K   E L+  ++
Sbjct: 1783 QLLQNSRVEAHILESRTENIEEEKQQLTRSLTQIEKEKRHLETQLTDEKMDKERLRARLK 1842

Query: 1087 EQDDQIKELK---------ETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXX 1137
            +Q  ++ +LK         E KL+  +   + E  ++ S  E   ++   +         
Sbjct: 1843 DQATEVTKLKEKLNEMIEEERKLSQLLQNSRVEAQMLESRAENTIEEKQQLKRVLSQVEE 1902

Query: 1138 XXXXLKVQEEEEFIQE---RSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQE 1194
                L+ Q  +E I     ++ L++Q+ ++ T+L+E   K+++ E   + L  +   +Q 
Sbjct: 1903 EKRLLETQLTDEKIDRERLKARLEDQATEV-TKLKEKLNKMVEDERKLSHLLQN---SQV 1958

Query: 1195 QINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTE 1254
            +   L+S+ E L  E   L  ++ ++         Q   E  ++ ++ L  R  DFQK +
Sbjct: 1959 ETQMLESRTENLEEEKQQLKRSLTQIEEEKRCLETQLTDE--KIDRERLRARLEDFQKDQ 2016

Query: 1255 HELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYA 1314
               ++       + E+L   V+   ++  +    + +       L+D+    R  +++ +
Sbjct: 2017 ---QILFEEKMGRAEKLGSRVRELEEQRDHLSAELRRKEREMEVLRDETLRERREKDRIS 2073

Query: 1315 DVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEEN 1374
             +++  +  +  +  +  +                  ++ + +  K+M+E  +  + +E 
Sbjct: 2074 SLLSDAKERKESLSVQVDSLQEQLVSLSRSKEQTKLKIQEQKEQNKEMREGLVAGL-QEM 2132

Query: 1375 AQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTI-TLTQRNDE 1433
            A LK+               + + + +++  + +  +K + I  K  +  +  L ++  E
Sbjct: 2133 ATLKELLEESHREGERLRSMMQERKDELVR-SREEGIKVAHIEAKDLQLKVQMLEKQKQE 2191

Query: 1434 FENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNV 1493
             E   Q  VE  K+  +   +++ +L   + K+       +++++  E E  +    L++
Sbjct: 2192 LETTLQLQVEQLKKKNEEGMQEKEQLQQRQEKLEGELMAMKSVKEHREAELTRAKARLDI 2251

Query: 1494 KITESVSLNKQVAELNKALEE 1514
               +   L+   AE  K  EE
Sbjct: 2252 LEDQRTELSSLAAERTKDAEE 2272



 Score =  139 bits (337), Expect = 5e-31
 Identities = 233/1236 (18%), Positives = 527/1236 (42%), Gaps = 89/1236 (7%)

Query: 151  IKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXX 210
            +++++  +S L+ +++ +E  I  L+  I +K++ +E  N+  +                
Sbjct: 1195 VQKREEVISDLKNRIQSLEVIIEKLETDIEQKNEQLELLNEQISQMKEREIEDQKELDRM 1254

Query: 211  XEDTKQQMTKMQENFIAMEAEWK---DEKQRLLKDIESKDVRISSLEEANKLLEAARFEI 267
             E+ K+Q  +++     +  +      EK+ LL+ IE +D  ++ L+      E   FE 
Sbjct: 1255 QENLKEQEKQLKRELDHLNIKMVGVIQEKEELLERIEERDGELTELQ-VKFTQEQRMFEQ 1313

Query: 268  SL--EHSKL----AQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANM 321
             L  EH+++    A+  E                 +Q +E    E+ + EE    ++  +
Sbjct: 1314 KLKAEHAEVNRCKAKIAEMEQDQVNLKERDEEQRKRQKMEERYREQKQTEELVQKDV-EV 1372

Query: 322  TELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTAS- 380
             +L  KIE L     Q R+   E +  L       +     ++     + +K        
Sbjct: 1373 RQLKLKIEELNQEIEQDRRIRMEQQEDLEQQTALLRDAEEEARTLKKTLQQKDKEERDRL 1432

Query: 381  KMKSPWSQLSSETLNQDTDKKINK-NEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXX 439
              +     L  E L++   + I   + + ++E  ++     L  KE  + E +       
Sbjct: 1433 HHEEKEKTLLKEKLHEAEQRNIKVLSSLQEIETTLEKERYQLRGKEERLMECNEELFLIK 1492

Query: 440  XXXXGKDTLIAQL-QLEHQQHMEGPSLI-HVGTNTEDVNEIAKVQEQLKQELND-EIKDV 496
                 +   I +L +L  +Q  E  +L   +    E+   ++K+ +  + E+   E +  
Sbjct: 1493 RERDQEKESIEELNKLIGEQGKEVKTLRGKLDERLEEEGRLSKLLQNQRVEVQVLESRAE 1552

Query: 497  NVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKE 556
            N+++  ++LK +  QI +    ++    +    K   +++L+     +   +K+ +  ++
Sbjct: 1553 NIEEEKQQLKRSLSQIEEEKRHLETQLTDEKVDKERLRVRLEDQATEVTKLNKILEEERK 1612

Query: 557  IVRLTE----ELHHLSQKVAELEEEKGNLQLHLVDYDSGRM-IESDVYKKMIEMENLA-- 609
            + +L +    E      +    EEEK  L+  L   +  +  +E+ +  + ++ E L   
Sbjct: 1613 LSQLLQNSRVEAQMFESRAQNTEEEKQLLKRSLSQIEREKSRLETQLTDEKMDKEKLKAR 1672

Query: 610  -ETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQI 668
             E + K ++ L+ +  ++++E   L Q    +++   +   L+S     E++   L+  +
Sbjct: 1673 LEDQDKEVTKLKEKMNEILEEERKLSQL---LQNSRVEAQMLESRAENIEVEKQQLKRSL 1729

Query: 669  DALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLE--K 726
              +   K+ L   + + K+DKE+L   ++D   +   +  KL   I+E   L+  L+  +
Sbjct: 1730 TQIEEEKRHLGTQLTDEKMDKERLRAWVEDQATEVTKLKEKLSEMIEEERKLSQLLQNSR 1789

Query: 727  MSAEKISELLAKINHEEQ--SKIQTQFGIDAKIQERDLYIENIESE-----LSKYKSRIC 779
            + A  +      I  E+Q  ++  TQ   + +  E  L  E ++ E     L    + + 
Sbjct: 1790 VEAHILESRTENIEEEKQQLTRSLTQIEKEKRHLETQLTDEKMDKERLRARLKDQATEVT 1849

Query: 780  RLEESIAVM--EDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVV 837
            +L+E +  M  E+R+ S   +  ++ + + E +   +E TI+E + + R+   ++     
Sbjct: 1850 KLKEKLNEMIEEERKLSQLLQNSRVEAQMLESR---AENTIEEKQQLKRVLSQVEE---- 1902

Query: 838  EKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQ 897
            EK+LLE +  ++++ ++      E+Q  +++   +++  N +VE   +      ++++ +
Sbjct: 1903 EKRLLETQLTDEKIDRERLKARLEDQATEVT--KLKEKLNKMVEDERKLSHL-LQNSQVE 1959

Query: 898  TQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIE-Y 956
            TQ+  LES  + +  E Q L    K+ +  +E E    +E+ + D+K+  E+    +E +
Sbjct: 1960 TQM--LESRTENLEEEKQQL----KRSLTQIEEEKRC-LETQLTDEKIDRERLRARLEDF 2012

Query: 957  VTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSP--DYTEQYINEINKL 1014
                +   +E     E L   V EL +    L  +  +K++      D T +   E +++
Sbjct: 2013 QKDQQILFEEKMGRAEKLGSRVRELEEQRDHLSAELRRKEREMEVLRDETLRERREKDRI 2072

Query: 1015 NALLKQKDEEIIALNQKINNAQVSYMSMV-SDYESKLAQFTTKLENME---------EEM 1064
            ++LL    E   +L+ ++++ Q   +S+  S  ++KL     K +N E         +EM
Sbjct: 2073 SSLLSDAKERKESLSVQVDSLQEQLVSLSRSKEQTKLKIQEQKEQNKEMREGLVAGLQEM 2132

Query: 1065 QRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDD 1124
              + + L +S +  E L+ +++E+ D++   +E  +     +   E   +   ++ +   
Sbjct: 2133 ATLKELLEESHREGERLRSMMQERKDELVRSREEGI----KVAHIEAKDLQLKVQMLEKQ 2188

Query: 1125 ANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTE 1184
               ++            LK ++ EE +QE+  LQ++  KL  EL    +     E   T 
Sbjct: 2189 KQELETTLQLQVEQ---LK-KKNEEGMQEKEQLQQRQEKLEGELMAMKSVKEHREAELTR 2244

Query: 1185 LTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEI---AELWKQ 1241
                  + ++Q  +L S   +   + + L +   +LR       + R  E     EL ++
Sbjct: 2245 AKARLDILEDQRTELSSLAAERTKDAEELSNRFRDLRLEADRLREDRIREKNNWEELKRE 2304

Query: 1242 HLAQREAD-----FQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQ 1296
            +  ++ A       +KT  E   ++   + KYE   +  + S + +      + Q+  + 
Sbjct: 2305 NKEKQNALEELELLRKTLMEKEKEMKLVKEKYE---NEKRRSERFQQGDEQNVRQIELVS 2361

Query: 1297 NKLQDKEEHLRNLQEK-YADVINQIEILRSEIEDEK 1331
             +L+DKE  L +++EK Y +   ++  L+ + EDEK
Sbjct: 2362 ERLRDKETELESIREKAYKEQSARLR-LQDQFEDEK 2396



 Score =  116 bits (278), Expect = 7e-24
 Identities = 241/1320 (18%), Positives = 559/1320 (42%), Gaps = 131/1320 (9%)

Query: 312  EKGSLEIANMTELTKK-IELLEHLN---CQIRQTN------KELENKLATMGTESKAVSS 361
            EK SLE   +T+L  + +EL E  N    QI+ T       KE+ + L     E++ ++ 
Sbjct: 437  EKESLE-QRITQLESEWVELQEQTNQGALQIKHTQELLNSEKEIVSSLRGQVEEAEKLTE 495

Query: 362  PSKKGSPLISRKSGRNTASKMKSP---WSQLSSETLNQDTDKKINKNEIAKLEMVIQSLN 418
              +K +  + R+  +    +++       ++ +E L      +       +L  +  +L 
Sbjct: 496  ELRKENEHMRRQREKQEEDRIQQDRERHKRMEAEMLESAQLCERESRTRLELHRLQVALE 555

Query: 419  KDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEI 478
            ++ +D+     E +            +++L+AQ   ++Q   E   L   G   E +  +
Sbjct: 556  RETLDRARAEQEAEQAKDALIKA---RESLLAQSSGQNQLKRE---LAGAGDALEKMAAL 609

Query: 479  AKVQEQLKQELNDEIK--DVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLK 536
             +   + K+EL       +  V +   ++++   +   L+ E+ A +  + +++   +  
Sbjct: 610  NEALAKDKRELGVRSLQLETEVAEAQAQIQAFGTETAGLHRELKAMSLEVHELRQRRESD 669

Query: 537  LKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIES 596
            LK +Q+  +   ++ ++  E+ R   +     ++ A  E++  + Q      +    +  
Sbjct: 670  LKALQQLREREREL-ENELELEREDRQ----REQTARTEDKSTDEQKISELTEQCSTVMK 724

Query: 597  DVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQ-- 654
            ++    +E+   AE + +A    E ++ DL++E   L+     +E +  +++Q++ +   
Sbjct: 725  ELQSVKVELLKAAELQRRA----ERERDDLMRESQRLEDTVCTLEREKEELAQVKEELRG 780

Query: 655  --VCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQN 712
              VC + +    +EQ   L     +L + ++ L   K+ L G I+ L+ D E    + + 
Sbjct: 781  VVVCLQKQMAQAQEQTSGLELKCIQLQMQVDTLTQTKDVLQGEIQCLQTDLERETAQKER 840

Query: 713  YIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELS 772
             +QE+++   K E+      SE        EQ    ++   +    +R    E  + E  
Sbjct: 841  ELQESIEERRKFEREIENWKSECKKFQRDVEQESENSKIQAEESKTDR----ERWQKERE 896

Query: 773  KYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQ----EKQKAYSEYTIQEDELVNRLA 828
               + + + +  + ++ +R   L ++ ++L  +L+    E +K  ++   ++     RL 
Sbjct: 897  SLSAELGQKDGEVEILRNRIDGLLKEKEELLDHLEKRNTELEKLQTKSAAEQKAAELRLR 956

Query: 829  VLMDHDRVVEKQLLEIEHENKELQKKNQILLE-ENQNLQISLSDMQQHYNALVEKANRTD 887
               D     +++  +++ E +EL +K    +E E+QNL+I+            EKA  +D
Sbjct: 957  GACDEVERWKERENKVQREKEELNQKFLERVERESQNLEITQR----------EKAKMSD 1006

Query: 888  LAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQ--IESAIRDKKV 945
            L + +  + + +  D+E        E +  +   +K IE LEIE   +  +ES +   + 
Sbjct: 1007 LMKKKEDEIRRRGEDIE--------ELKLKLQSNEKTIESLEIELQQKETLESRVETLEK 1058

Query: 946  LNEKY-EKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYT 1004
            LN +  EK ++ + + E++ Q+ ++  E      E   +  LE  D+ + + +++     
Sbjct: 1059 LNTQLKEKKLDKIRENESR-QKKRDEQER---EKEVRWRRQLEQKDEGLIELKSR----I 1110

Query: 1005 EQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEM 1064
            ++ I E   ++ L+++++++I  L   ++  + +    + +       +  +  NME+  
Sbjct: 1111 DELIGEKEHISLLVEEREKDIEQLQSTLSTEKRALELRLKEARDNAEWWKRRAGNMEKVK 1170

Query: 1065 QRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDD 1124
            + V++    +++   EL  L+RE+++++++ +E     +  I   E  +I   +E   + 
Sbjct: 1171 ESVNRV---AEREKTELSELLREREEEVQKREEVISDLKNRIQSLE--VIIEKLETDIEQ 1225

Query: 1125 ANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKII-------- 1176
             N                ++++++E  + +  L+EQ  +L  EL     K++        
Sbjct: 1226 KNEQLELLNEQISQMKEREIEDQKELDRMQENLKEQEKQLKRELDHLNIKMVGVIQEKEE 1285

Query: 1177 ---QLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGF 1233
               ++E  + ELT   V   ++    + KL+  + E +   + +AE+       V+ +  
Sbjct: 1286 LLERIEERDGELTELQVKFTQEQRMFEQKLKAEHAEVNRCKAKIAEME---QDQVNLKER 1342

Query: 1234 EIAELWKQHLAQREADFQKTEHELR--VQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQ 1291
            +  +  +Q + +R  + ++TE  ++  V++   + K E+L   ++   +    +   +EQ
Sbjct: 1343 DEEQRKRQKMEERYREQKQTEELVQKDVEVRQLKLKIEELNQEIEQDRRIRMEQQEDLEQ 1402

Query: 1292 VTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXD 1351
             T+L   L+D EE  R L++       +        E EK                    
Sbjct: 1403 QTAL---LRDAEEEARTLKKTLQQKDKEERDRLHHEEKEKTLLKEKLHEAEQRNIKVLSS 1459

Query: 1352 LR-----TENQSYK-QMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLEL 1405
            L+      E + Y+ + +E+ ++  NEE   +K+               + +   +V  L
Sbjct: 1460 LQEIETTLEKERYQLRGKEERLMECNEELFLIKRERDQEKESIEELNKLIGEQGKEVKTL 1519

Query: 1406 THQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLK 1465
              +L   D  + ++         + +   +N R ++   E R E++  EK+ +L     +
Sbjct: 1520 RGKL---DERLEEE--------GRLSKLLQNQRVEVQVLESRAENIEEEKQ-QLKRSLSQ 1567

Query: 1466 MHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTA 1525
            + E   H ET   + ++++    E L V++ +  +   +V +LNK LEEE     ++   
Sbjct: 1568 IEEEKRHLETQLTDEKVDK----ERLRVRLEDQAT---EVTKLNKILEEE----RKLSQL 1616

Query: 1526 LENQEIEIVTLNDEITNLQ---NMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLD 1582
            L+N  +E         N +    +++ S S+I++  S      Q  DE++D    K  L+
Sbjct: 1617 LQNSRVEAQMFESRAQNTEEEKQLLKRSLSQIEREKSRLE--TQLTDEKMDKEKLKARLE 1674



 Score = 72.9 bits (171), Expect = 7e-11
 Identities = 191/995 (19%), Positives = 409/995 (41%), Gaps = 76/995 (7%)

Query: 146  HLSNTIKEKDNALSVLQVKMKIMETTILDLQEKIN---EKDQIIEAKNKATTXXXXXXXX 202
            HL   + ++      L+ ++K   T +  L+EK+N   E+++ +    + +         
Sbjct: 1822 HLETQLTDEKMDKERLRARLKDQATEVTKLKEKLNEMIEEERKLSQLLQNSRVEAQMLES 1881

Query: 203  XXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEK---QRLLKDIESKDVRISSL-EEANK 258
                     +  K+ +++++E    +E +  DEK   +RL   +E +   ++ L E+ NK
Sbjct: 1882 RAENTIEEKQQLKRVLSQVEEEKRLLETQLTDEKIDRERLKARLEDQATEVTKLKEKLNK 1941

Query: 259  LLEAARFEISLEHSKLAQELE-QXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLE 317
            ++E  R    L H     ++E Q                K+S+    EEK  +E + + E
Sbjct: 1942 MVEDER---KLSHLLQNSQVETQMLESRTENLEEEKQQLKRSLTQIEEEKRCLETQLTDE 1998

Query: 318  IANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSG-- 375
              +   L  ++E  +  + QI    +E   +   +G+  + +       S  + RK    
Sbjct: 1999 KIDRERLRARLEDFQK-DQQI--LFEEKMGRAEKLGSRVRELEEQRDHLSAELRRKEREM 2055

Query: 376  ---RNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISE-K 431
               R+   + +    ++SS   +    K+    ++  L+  + SL++     +  I E K
Sbjct: 2056 EVLRDETLRERREKDRISSLLSDAKERKESLSVQVDSLQEQLVSLSRSKEQTKLKIQEQK 2115

Query: 432  DTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELND 491
            +           G   +    +L  + H EG  L  +    +D  E+ + +E+  +  + 
Sbjct: 2116 EQNKEMREGLVAGLQEMATLKELLEESHREGERLRSMMQERKD--ELVRSREEGIKVAHI 2173

Query: 492  EIKDVNVK-DLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKV 550
            E KD+ +K  ++EK K   E   QL  E     KN  +     K +L+Q Q+ ++     
Sbjct: 2174 EAKDLQLKVQMLEKQKQELETTLQLQVE-QLKKKN--EEGMQEKEQLQQRQEKLEGELMA 2230

Query: 551  SDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKM-IEMENLA 609
              S KE      EL     ++  LE+++  L     +        S+ ++ + +E + L 
Sbjct: 2231 MKSVKE--HREAELTRAKARLDILEDQRTELSSLAAERTKDAEELSNRFRDLRLEADRLR 2288

Query: 610  ETRLKAISLLE------SQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVH 663
            E R++  +  E       +K + ++EL +L++   E E ++    +L  ++  +E +   
Sbjct: 2289 EDRIREKNNWEELKRENKEKQNALEELELLRKTLMEKEKEM----KLVKEKYENEKRRSE 2344

Query: 664  LEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDK 723
              +Q D    + +++ LV E L+ DKE    +I++    ++    +LQ+  ++   +T K
Sbjct: 2345 RFQQGD--EQNVRQIELVSERLR-DKETELESIREKAYKEQSARLRLQDQFEDEKRVTKK 2401

Query: 724  LEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEE 783
            L     EK+ E L K+  E ++K++         ++++  +        K  S    L +
Sbjct: 2402 LR----EKL-ETLEKVKQEMKTKMENDIRYFRDSEKKNNGL--------KMDSGHGTLAD 2448

Query: 784  SIAVMEDRRYSLE-RKADQLGSYLQEKQKAYSEYTIQEDEL---VNRLAVLMDHDRVVEK 839
            S+ +  + R  ++  +AD L   L +K +      I+ + L   ++RL  L+ +   ++ 
Sbjct: 2449 SLEINAEYRSHVKLLEADTLRKDLTKKDQEIRRLRIKAETLQTEIDRLHSLLKNGN-MKT 2507

Query: 840  QLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQ 899
               E E  ++E Q+ + ILLE+ +  ++ L +      AL E+A        +  + +  
Sbjct: 2508 GPTENEDWDREKQQVSTILLEKEERDRL-LREKDVEVYALKERAEE---MSKDRDRVRIA 2563

Query: 900  LRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQ 959
            L   E+ L  I ++ +    + K++    +I         +  +  ++ +     + V Q
Sbjct: 2564 LEKTEAML--IYYKERLGHQEHKRKQTGGDISLEKVSADELDTESAVHGRLSAMQQAVAQ 2621

Query: 960  LEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLK 1019
            LE Q    +    +L   +E L      L +   Q +  +     +  ++E   L+  + 
Sbjct: 2622 LEVQQNLLEKKNSHLEKKIERLRTERQHLRETLTQVELERGKLRRQLSLSEAGVLDQSVG 2681

Query: 1020 QKDEEIIALNQKIN--NAQVSYMSMV--SDYESKLAQFTTKLENMEE--EMQRVSKQLLD 1073
              D E+  L  + N    QV ++ ++   D+  +       L+N +    +++   + L 
Sbjct: 2682 TDDAELKHLRVRANELEEQVHHLRLMLAVDHRQRAEFIDRSLKNSQSLMSLRQDLNESLS 2741

Query: 1074 SKQHNEELQILVREQ---DDQIKELKETKLTFEMN 1105
            +      L +L  E    D  I+E +E +LTF  +
Sbjct: 2742 AVSQRPVLSVLESETQRLDRSIRE-EELRLTFSQS 2775



 Score = 62.1 bits (144), Expect = 1e-07
 Identities = 126/630 (20%), Positives = 259/630 (41%), Gaps = 46/630 (7%)

Query: 952  KNIEYVTQLEAQLQEYKNNIENLNMNVEELN----KMNLELIDKH---VQKQQTQSPDYT 1004
            K+ E    +E++  E +N I  LNM V+ L     K   E+  +H   ++++Q Q   + 
Sbjct: 299  KSSELKADIESETLELRNRITELNMTVKALESEREKQEEEMERRHRHEMEREQEQERKWE 358

Query: 1005 EQYINEINKLNALLKQKDEEIIALNQKIN--NAQVSYMSMVSD----YESKLAQFTTKLE 1058
             Q   E N  +     K      L+QK++  ++ +S     SD      S +AQ  T L+
Sbjct: 359  RQMELERNFESVCQAVKTLSRALLSQKMSGESSSLSADDASSDGLCSVLSVIAQAETALQ 418

Query: 1059 NMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMI----- 1113
              E+E+Q     L       E L+  + + + +  EL+E      + I  T+ ++     
Sbjct: 419  WREQEVQEAQMSLRRLGTEKESLEQRITQLESEWVELQEQTNQGALQIKHTQELLNSEKE 478

Query: 1114 ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYT 1173
            I S++    ++A  +              + ++EE+ IQ+    +E+  ++  E+ E   
Sbjct: 479  IVSSLRGQVEEAEKLTEELRKENEHMRRQREKQEEDRIQQD---RERHKRMEAEMLES-A 534

Query: 1174 KIIQLETLNTELTGHDV-VNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRG 1232
            ++ + E+  T L  H + V  E+    +++ EQ   +  + L    E   + SS  +Q  
Sbjct: 535  QLCERES-RTRLELHRLQVALERETLDRARAEQEAEQAKDALIKARESLLAQSSGQNQLK 593

Query: 1233 FEIA---ELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETN----- 1284
             E+A   +  ++  A  EA   K + EL V+    E++  +    +Q+   E        
Sbjct: 594  RELAGAGDALEKMAALNEA-LAKDKRELGVRSLQLETEVAEAQAQIQAFGTETAGLHREL 652

Query: 1285 KIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXX 1344
            K +++E V  L+ + +   + L+ L+E+  ++ N++E+ R + + E+ A           
Sbjct: 653  KAMSLE-VHELRQRRESDLKALQQLRERERELENELELEREDRQREQTA----RTEDKST 707

Query: 1345 XXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLE 1404
                  +L TE  S    + QS+     + A+L++ +            R+ D    +  
Sbjct: 708  DEQKISEL-TEQCSTVMKELQSVKVELLKAAELQRRAERERDDLMRESQRLEDTVCTLER 766

Query: 1405 LTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEK---ESELAI 1461
               +L     E+          + Q  ++   +  + ++ + +++ LT  K   + E+  
Sbjct: 767  EKEELAQVKEELRGVVVCLQKQMAQAQEQTSGLELKCIQLQMQVDTLTQTKDVLQGEIQC 826

Query: 1462 LRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAE--LNKALEEEVAKT 1519
            L+  +       E   +ES  ER K   E+    +E     + V +   N  ++ E +KT
Sbjct: 827  LQTDLERETAQKERELQESIEERRKFEREIENWKSECKKFQRDVEQESENSKIQAEESKT 886

Query: 1520 N--EMQTALENQEIEIVTLNDEITNLQNMV 1547
            +    Q   E+   E+   + E+  L+N +
Sbjct: 887  DRERWQKERESLSAELGQKDGEVEILRNRI 916


>UniRef50_Q9FJ35 Cluster: Myosin heavy chain-like protein; n=2;
            Arabidopsis thaliana|Rep: Myosin heavy chain-like protein
            - Arabidopsis thaliana (Mouse-ear cress)
          Length = 1305

 Score =  158 bits (384), Expect = 1e-36
 Identities = 223/1131 (19%), Positives = 491/1131 (43%), Gaps = 74/1131 (6%)

Query: 484  QLKQ-ELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQK 542
            Q+K+ E + E  +  V D  + L +AEE+   L+ +I A   N I+   N   +L     
Sbjct: 67   QVKELEAHIESSEKLVADFTQSLNNAEEEKKLLSQKI-AELSNEIQEAQNTMQELMSESG 125

Query: 543  TIDNFSKVSDSNKEIVRLTEELHHL--SQKVAELEEEKGNLQLHLVDYDSGRMIESDVYK 600
             +     V +     +R   E+H    S + +ELE +  + +  + D  S  +  ++   
Sbjct: 126  QLKESHSVKERELFSLRDIHEIHQRDSSTRASELEAQLESSKQQVSDL-SASLKAAEEEN 184

Query: 601  KMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQL-QSDQVCSEI 659
            K I  +N+ ET  K +   ++   +L+ EL  L+  + E E +L+ + ++ ++ Q  S I
Sbjct: 185  KAISSKNV-ETMNK-LEQTQNTIQELMAELGKLKDSHREKESELSSLVEVHETHQRDSSI 242

Query: 660  KSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMD 719
                LEEQ+++      EL   + N + +K+ L   I +L N+ ++  N +Q  + E+  
Sbjct: 243  HVKELEEQVESSKKLVAELNQTLNNAEEEKKVLSQKIAELSNEIKEAQNTIQELVSESGQ 302

Query: 720  LTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRIC 779
            L +       +  S  L  I+   Q +  T      ++ E +  +E+ E  +S     + 
Sbjct: 303  LKESHSVKDRDLFS--LRDIHETHQRESST------RVSELEAQLESSEQRISDLTVDLK 354

Query: 780  RLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDH-DRVVE 838
              EE    +  +   +  K +Q  + ++E      E   +  E  + L+ L+   D+ V 
Sbjct: 355  DAEEENKAISSKNLEIMDKLEQAQNTIKELMDELGELKDRHKEKESELSSLVKSADQQVA 414

Query: 839  KQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQT 898
                 +++  +E +  +Q +L+ +  +Q +   +Q+H +   +      + E E T    
Sbjct: 415  DMKQSLDNAEEEKKMLSQRILDISNEIQEAQKTIQEHMSESEQLKESHGVKERELTG--- 471

Query: 899  QLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVT 958
             LRD+    +R +    + +  + K +E   ++ +  + +A  +KK L+    +  + + 
Sbjct: 472  -LRDIHETHQRESSTRLSELETQLKLLEQRVVDLSASLNAAEEEKKSLSSMILEITDELK 530

Query: 959  QLEAQLQEYKNNI-ENLNMNVEELNKMN--LELIDKHVQKQQTQSPDY---TEQYINEIN 1012
            Q ++++QE    + E+ +   ++ N+++  +E+ + H +   +Q  +     E    ++ 
Sbjct: 531  QAQSKVQELVTELAESKDTLTQKENELSSFVEVHEAHKRDSSSQVKELEARVESAEEQVK 590

Query: 1013 KLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLL 1072
            +LN  L   +EE   L+Q+I+   +      S  + +L+  + +L+    E       L 
Sbjct: 591  ELNQNLNSSEEEKKILSQQISEMSIKIKRAESTIQ-ELSSESERLKGSHAEKDNELFSLR 649

Query: 1073 DSKQ-HNEELQILVREQDDQIK--ELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVD 1129
            D  + H  EL   +R  + Q++  E +  +L+  +   + E   +S+ I   SD+     
Sbjct: 650  DIHETHQRELSTQLRGLEAQLESSEHRVLELSESLKAAEEESRTMSTKISETSDELERTQ 709

Query: 1130 XXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHD 1189
                        LK Q  E+   +  +L E+ +K   +++E    +  LE L  E     
Sbjct: 710  IMVQELTADSSKLKEQLAEKE-SKLFLLTEKDSKSQVQIKELEATVATLE-LELESVRAR 767

Query: 1190 VVNQE-QINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQ---HLAQ 1245
            +++ E +I    + +EQL  +N  +++ ++EL  ++    ++RG E++ L ++   +  Q
Sbjct: 768  IIDLETEIASKTTVVEQLEAQNREMVARISELEKTM----EERGTELSALTQKLEDNDKQ 823

Query: 1246 READFQKTEHE---LRVQLSAFESKYEQLLDSVQSSTQEETNKIVTME--------QVTS 1294
              +  +    E   LR +L +   + E++   +   ++E + KI  ++        QV S
Sbjct: 824  SSSSIETLTAEIDGLRAELDSMSVQKEEVEKQMVCKSEEASVKIKRLDDEVNGLRQQVAS 883

Query: 1295 LQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDE-KVAFXXXXXXXXXXXXXXXXDLR 1353
            L ++  + E  L    E+ ++ ++QI  L+ EI ++ KV                  +L 
Sbjct: 884  LDSQRAELEIQLEKKSEEISEYLSQITNLKEEIINKVKVHESILEEINGLSEKIKGRELE 943

Query: 1354 TENQSYKQMQ-EQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELK 1412
             E    ++ + ++ +    EEN Q+                 +N+ + ++  L  Q    
Sbjct: 944  LETLGKQRSELDEELRTKKEENVQMHDKINVASSEIMALTELINNLKNELDSLQVQKSET 1003

Query: 1413 DSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANH 1472
            ++E+ ++  E +    + +++  +V++ LVE E     L  E+  ++  L  +     N 
Sbjct: 1004 EAELEREKQEKS----ELSNQITDVQKALVEQEAAYNTLE-EEHKQINELFKETEATLNK 1058

Query: 1473 YETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIE 1532
                 KE++    +L+EE   ++T   S           + EE  ++   +  ++  EIE
Sbjct: 1059 VTVDYKEAQ----RLLEERGKEVTSRDS--------TIGVHEETMESLRNELEMKGDEIE 1106

Query: 1533 IVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQG-RDEQLDNTMNKELLD 1582
              TL ++I+N++  +R S+ K++      ++ ++  R E+  +   + LL+
Sbjct: 1107 --TLMEKISNIEVKLRLSNQKLRVTEQVLTEKEEAFRKEEAKHLEEQALLE 1155



 Score =  138 bits (334), Expect = 1e-30
 Identities = 211/994 (21%), Positives = 431/994 (43%), Gaps = 102/994 (10%)

Query: 607  NLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEE 666
            N AE   K++SL  S+  D++Q+    Q    E+  +L ++ +   ++       V L +
Sbjct: 2    NSAEEENKSLSLKVSEISDVIQQG---QTTIQELISELGEMKEKYKEKESEHSSLVELHK 58

Query: 667  QIDALSASK-KELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLE 725
              +  S+S+ KEL   IE+ +        ++ + E +K+ +  K+     E  +  + ++
Sbjct: 59   THERESSSQVKELEAHIESSEKLVADFTQSLNNAEEEKKLLSQKIAELSNEIQEAQNTMQ 118

Query: 726  KMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERD--LYIENIESELSKYKSRICRLEE 783
            ++ +E   +L  K +H  + +         +I +RD       +E++L   K ++  L  
Sbjct: 119  ELMSES-GQL--KESHSVKERELFSLRDIHEIHQRDSSTRASELEAQLESSKQQVSDLSA 175

Query: 784  SIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLE 843
            S+   E+   ++  K  +  + L++ Q      TIQE  L+  L  L D  R  E +L  
Sbjct: 176  SLKAAEEENKAISSKNVETMNKLEQTQN-----TIQE--LMAELGKLKDSHREKESELSS 228

Query: 844  IEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRT-DLAESESTKYQTQLRD 902
            +   ++  Q+ + I ++E       L +  +    LV + N+T + AE E      ++ +
Sbjct: 229  LVEVHETHQRDSSIHVKE-------LEEQVESSKKLVAELNQTLNNAEEEKKVLSQKIAE 281

Query: 903  LESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEY-VTQLE 961
            L + +K   +  Q L+ +  +  E   ++       ++RD   ++E +++     V++LE
Sbjct: 282  LSNEIKEAQNTIQELVSESGQLKESHSVKDRDLF--SLRD---IHETHQRESSTRVSELE 336

Query: 962  AQLQEYKNNIENLNMNV---EELNKM----NLELIDKHVQKQQTQSPDYTEQYINEINKL 1014
            AQL+  +  I +L +++   EE NK     NLE++DK  Q Q T      ++ ++E+ +L
Sbjct: 337  AQLESSEQRISDLTVDLKDAEEENKAISSKNLEIMDKLEQAQNT-----IKELMDELGEL 391

Query: 1015 NALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDS 1074
                K+K+ E+               S+V   + ++A     L+N EEE + +S+++LD 
Sbjct: 392  KDRHKEKESEL--------------SSLVKSADQQVADMKQSLDNAEEEKKMLSQRILDI 437

Query: 1075 KQHNEELQILVRE---QDDQIKE---LKETKLTFEMNIPKTEGMIISSTIEPMSDDANNV 1128
                +E Q  ++E   + +Q+KE   +KE +LT   +I +T     S+ +  +      +
Sbjct: 438  SNEIQEAQKTIQEHMSESEQLKESHGVKERELTGLRDIHETHQRESSTRLSELETQLKLL 497

Query: 1129 DXXXXXXXXXXXXLKVQEEE------EFIQERSVLQEQSAKLNTELQECYTKIIQLET-L 1181
            +             + +++       E   E    Q +  +L TEL E    + Q E  L
Sbjct: 498  EQRVVDLSASLNAAEEEKKSLSSMILEITDELKQAQSKVQELVTELAESKDTLTQKENEL 557

Query: 1182 NTELTGHDVVNQEQINQLK-------SKLEQLNTENDNLLSTVAELRSSISSAVDQRGFE 1234
            ++ +  H+   ++  +Q+K       S  EQ+   N NL S+  E +  +S  + +   +
Sbjct: 558  SSFVEVHEAHKRDSSSQVKELEARVESAEEQVKELNQNLNSSEEE-KKILSQQISEMSIK 616

Query: 1235 I--AELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTME-Q 1291
            I  AE   Q L+      + +  E   +L +    +E     + +  +    ++ + E +
Sbjct: 617  IKRAESTIQELSSESERLKGSHAEKDNELFSLRDIHETHQRELSTQLRGLEAQLESSEHR 676

Query: 1292 VTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXD 1351
            V  L   L+  EE  R +  K ++  +++E  R++I  +++                   
Sbjct: 677  VLELSESLKAAEEESRTMSTKISETSDELE--RTQIMVQELTADSSKLKEQLAEKESKLF 734

Query: 1352 LRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELT---HQ 1408
            L TE  S  Q+Q +          +L+ +             R+ D E ++   T    Q
Sbjct: 735  LLTEKDSKSQVQIK----------ELEATVATLELELESVRARIIDLETEIASKTTVVEQ 784

Query: 1409 LELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKR----IEDLTYEKE---SELAI 1461
            LE ++ E+  +  E   T+ +R  E   + Q+L + +K+    IE LT E +   +EL  
Sbjct: 785  LEAQNREMVARISELEKTMEERGTELSALTQKLEDNDKQSSSSIETLTAEIDGLRAELDS 844

Query: 1462 LRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNE 1521
            + ++  E         +E+ ++  +L +E+N    +  SL+ Q AEL   LE++  + +E
Sbjct: 845  MSVQKEEVEKQMVCKSEEASVKIKRLDDEVNGLRQQVASLDSQRAELEIQLEKKSEEISE 904

Query: 1522 MQTALENQEIEIVTLNDEITNLQNMVRASSSKIQ 1555
              + + N + EI+       ++   +   S KI+
Sbjct: 905  YLSQITNLKEEIINKVKVHESILEEINGLSEKIK 938



 Score =  119 bits (286), Expect = 8e-25
 Identities = 189/1039 (18%), Positives = 438/1039 (42%), Gaps = 61/1039 (5%)

Query: 84   RPFVPGISESLANTLKQKEILMEKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQ--L 141
            +  V  ++++L N  ++K++L +KI +     K +  TI                    L
Sbjct: 255  KKLVAELNQTLNNAEEEKKVLSQKIAELSNEIKEAQNTIQELVSESGQLKESHSVKDRDL 314

Query: 142  GDVTHLSNTI-KEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXX 200
              +  +  T  +E    +S L+ +++  E  I DL   ++ KD   E +NKA +      
Sbjct: 315  FSLRDIHETHQRESSTRVSELEAQLESSEQRISDLT--VDLKDA--EEENKAISSKNLEI 370

Query: 201  XXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLL 260
                       ++   ++ ++++     E+E     +   + +      + + EE  K+L
Sbjct: 371  MDKLEQAQNTIKELMDELGELKDRHKEKESELSSLVKSADQQVADMKQSLDNAEEEKKML 430

Query: 261  EAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIAN 320
                 +IS E  + AQ+  Q              + ++ +     +  E  ++ S     
Sbjct: 431  SQRILDISNEIQE-AQKTIQEHMSESEQLKESHGVKERELT-GLRDIHETHQRESS--TR 486

Query: 321  MTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTAS 380
            ++EL  +++LLE     +  +    E +  ++ +    ++   K+    +         S
Sbjct: 487  LSELETQLKLLEQRVVDLSASLNAAEEEKKSLSSMILEITDELKQAQSKVQELVTELAES 546

Query: 381  K--MKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXX 438
            K  +    ++LSS     +  K+ + +++ +LE  ++S  + + +    ++  +      
Sbjct: 547  KDTLTQKENELSSFVEVHEAHKRDSSSQVKELEARVESAEEQVKELNQNLNSSEEEKKIL 606

Query: 439  XXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNV 498
                      I + +   Q+ +   S    G++ E  NE+  +++    E +       +
Sbjct: 607  SQQISEMSIKIKRAESTIQE-LSSESERLKGSHAEKDNELFSLRDI--HETHQRELSTQL 663

Query: 499  KDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVS-DSNKEI 557
            + L  +L+S+E ++ +L++ + AA +    + +       ++++T     +++ DS+K  
Sbjct: 664  RGLEAQLESSEHRVLELSESLKAAEEESRTMSTKISETSDELERTQIMVQELTADSSK-- 721

Query: 558  VRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSG----RMIESDVYKKMIEMENLAETRL 613
              L E+L     K+  L E+    Q+ + + ++      +    V  ++I++E    ++ 
Sbjct: 722  --LKEQLAEKESKLFLLTEKDSKSQVQIKELEATVATLELELESVRARIIDLETEIASKT 779

Query: 614  KAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVH-LEEQIDALS 672
              +  LE+Q  ++V  +  L++  +E   +L+ ++Q   D       S+  L  +ID L 
Sbjct: 780  TVVEQLEAQNREMVARISELEKTMEERGTELSALTQKLEDNDKQSSSSIETLTAEIDGLR 839

Query: 673  ASKKELALVIENLKLD----KEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMS 728
            A    +++  E ++       E+    IK L+++   +  ++ +   +  +L  +LEK S
Sbjct: 840  AELDSMSVQKEEVEKQMVCKSEEASVKIKRLDDEVNGLRQQVASLDSQRAELEIQLEKKS 899

Query: 729  AEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVM 788
             E+ISE L++I + ++  I        K++  +  +E I     K K R   LE      
Sbjct: 900  -EEISEYLSQITNLKEEIIN-------KVKVHESILEEINGLSEKIKGRELELETLGKQR 951

Query: 789  EDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHEN 848
             +    L  K ++    + +K    S   +   EL+N L   +D  +V +K   E E E 
Sbjct: 952  SELDEELRTKKEE-NVQMHDKINVASSEIMALTELINNLKNELDSLQV-QKSETEAELE- 1008

Query: 849  KELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLK 908
            +E Q+K+++    NQ     ++D+Q+   ALVE+    +  E E  +     ++ E+ L 
Sbjct: 1009 REKQEKSEL---SNQ-----ITDVQK---ALVEQEAAYNTLEEEHKQINELFKETEATLN 1057

Query: 909  RIT---HEHQTLIVQKKKEI--EDLEIEFNTQIESAIRDK-KVLNEKYEKNIEYVTQLEA 962
            ++T    E Q L+ ++ KE+   D  I  + +   ++R++ ++  ++ E  +E ++ +E 
Sbjct: 1058 KVTVDYKEAQRLLEERGKEVTSRDSTIGVHEETMESLRNELEMKGDEIETLMEKISNIEV 1117

Query: 963  QLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYT---EQYINEINKLNALLK 1019
            +L+     +      + E  +   +   KH+++Q     + T   E Y   I ++   + 
Sbjct: 1118 KLRLSNQKLRVTEQVLTEKEEAFRKEEAKHLEEQALLEKNLTMTHETYRGMIKEIADKVN 1177

Query: 1020 QKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNE 1079
               +   ++++K+   Q  Y   V +    L   T  +     E ++++K++    +  +
Sbjct: 1178 ITVDGFQSMSEKLTEKQGRYEKTVMEASKILWTATNWVIERNHEKEKMNKEIEKKDEEIK 1237

Query: 1080 ELQILVREQDDQIKELKET 1098
            +L   VRE + + + +KET
Sbjct: 1238 KLGGKVREDEKEKEMMKET 1256



 Score =  103 bits (246), Expect = 5e-20
 Identities = 188/992 (18%), Positives = 412/992 (41%), Gaps = 85/992 (8%)

Query: 141  LGDVTHLSNTIKEKDNALSVL----QVKMKIMETTILDLQEKINEKDQIIEAKNKATTXX 196
            + ++  L ++ +EK++ LS L    +   +     + +L+E++    +++   N+     
Sbjct: 209  MAELGKLKDSHREKESELSSLVEVHETHQRDSSIHVKELEEQVESSKKLVAELNQTLNNA 268

Query: 197  XXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDE---KQR---LLKDIESKDVRI 250
                            + K+    +QE  ++   + K+    K R    L+DI     R 
Sbjct: 269  EEEKKVLSQKIAELSNEIKEAQNTIQE-LVSESGQLKESHSVKDRDLFSLRDIHETHQRE 327

Query: 251  SS--LEEANKLLEAARFEIS--LEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEE 306
            SS  + E    LE++   IS      K A+E  +               A+ +I+   +E
Sbjct: 328  SSTRVSELEAQLESSEQRISDLTVDLKDAEEENKAISSKNLEIMDKLEQAQNTIKELMDE 387

Query: 307  KTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKG 366
              E++++   + + ++ L K  +        ++Q+    E +   +      +S+  ++ 
Sbjct: 388  LGELKDRHKEKESELSSLVKSAD---QQVADMKQSLDNAEEEKKMLSQRILDISNEIQEA 444

Query: 367  SPLISRKSGRNTASKMKSPWSQLSSETLNQ--DTDKKINKNEIAKLEMVIQSLNKDLVDK 424
               I      +   K      +     L    +T ++ +   +++LE  ++ L + +VD 
Sbjct: 445  QKTIQEHMSESEQLKESHGVKERELTGLRDIHETHQRESSTRLSELETQLKLLEQRVVDL 504

Query: 425  EYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQ 484
               ++  +                + Q Q + Q+ +         T T+  NE++   E 
Sbjct: 505  SASLNAAEEEKKSLSSMILEITDELKQAQSKVQE-LVTELAESKDTLTQKENELSSFVEV 563

Query: 485  LKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAAN---KNMIKVKSNHKLKLKQMQ 541
             +    D    V  K+L  +++SAEEQ+ +LN  ++++    K + +  S   +K+K+ +
Sbjct: 564  HEAHKRDSSSQV--KELEARVESAEEQVKELNQNLNSSEEEKKILSQQISEMSIKIKRAE 621

Query: 542  KTIDNFSKVSDSNK-EIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYK 600
             TI   S  S+  K        EL  L + + E  + + + QL  ++      +ES  ++
Sbjct: 622  STIQELSSESERLKGSHAEKDNELFSL-RDIHETHQRELSTQLRGLE----AQLESSEHR 676

Query: 601  KMIEMENL--AETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSE 658
             +   E+L  AE   + +S   S+  D ++   I+      V++  AD S+L+      E
Sbjct: 677  VLELSESLKAAEEESRTMSTKISETSDELERTQIM------VQELTADSSKLKEQLAEKE 730

Query: 659  IKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLEND---KEDIMNKLQNYIQ 715
             K   L E+        KEL   +  L+L+ E +   I DLE +   K  ++ +L+   +
Sbjct: 731  SKLFLLTEKDSKSQVQIKELEATVATLELELESVRARIIDLETEIASKTTVVEQLEAQNR 790

Query: 716  ENMDLTDKLEKMSAEKISELLA---KINHEEQ---SKIQTQF----GIDAKIQERDLYIE 765
            E +    +LEK   E+ +EL A   K+   ++   S I+T      G+ A++    +  E
Sbjct: 791  EMVARISELEKTMEERGTELSALTQKLEDNDKQSSSSIETLTAEIDGLRAELDSMSVQKE 850

Query: 766  NIESEL----SKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQ-- 819
             +E ++     +   +I RL++ +  +  +  SL+ +  +L   L++K +  SEY  Q  
Sbjct: 851  EVEKQMVCKSEEASVKIKRLDDEVNGLRQQVASLDSQRAELEIQLEKKSEEISEYLSQIT 910

Query: 820  --EDELVNRL----AVLMDHDRVVEK---QLLEIE---HENKELQKKNQILLEENQNLQI 867
              ++E++N++    ++L + + + EK   + LE+E    +  EL ++ +   EEN  +  
Sbjct: 911  NLKEEIINKVKVHESILEEINGLSEKIKGRELELETLGKQRSELDEELRTKKEENVQMHD 970

Query: 868  SLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTL---IVQKKKE 924
             ++       AL E  N     ++E    Q Q  + E+ L+R   E   L   I   +K 
Sbjct: 971  KINVASSEIMALTELINN---LKNELDSLQVQKSETEAELEREKQEKSELSNQITDVQKA 1027

Query: 925  IEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNK- 983
            + + E  +NT  E    + K +NE +++    + ++    +E +  +E     V   +  
Sbjct: 1028 LVEQEAAYNTLEE----EHKQINELFKETEATLNKVTVDYKEAQRLLEERGKEVTSRDST 1083

Query: 984  --MNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMS 1041
              ++ E ++  ++ +     D  E  + +I+ +   L+  ++++    Q +   + ++  
Sbjct: 1084 IGVHEETMES-LRNELEMKGDEIETLMEKISNIEVKLRLSNQKLRVTEQVLTEKEEAFRK 1142

Query: 1042 MVSDYESKLAQFTTKLENMEEEMQRVSKQLLD 1073
              + +  + A     L    E  + + K++ D
Sbjct: 1143 EEAKHLEEQALLEKNLTMTHETYRGMIKEIAD 1174


>UniRef50_A2EUG5 Cluster: Putative uncharacterized protein; n=3;
            Trichomonas vaginalis G3|Rep: Putative uncharacterized
            protein - Trichomonas vaginalis G3
          Length = 1548

 Score =  158 bits (384), Expect = 1e-36
 Identities = 254/1300 (19%), Positives = 585/1300 (45%), Gaps = 122/1300 (9%)

Query: 312  EKGSLEIANMTELTKKI-ELLEHLNCQIRQT-NKELENKLATMGTESKAVSSPSKKGSPL 369
            +  ++++ NM E  + + + L  L+ ++ +   +E++  +  +G     +S      S  
Sbjct: 53   KNSNMQVDNMKEQIQNLTQNLIDLSSKVEKIIPEEIKTAVPNLGQSDYVISVVQHLSSLY 112

Query: 370  ISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQS---LNKDLVDKEY 426
            I++ S + T+S ++   S   S  L  +  K  N    A +E +  S    N+ + + E 
Sbjct: 113  IAKTSSQYTSSVIQKLNSDNQSIILQNEQLKSENSQLKATIEALHASEMQRNRKIQESER 172

Query: 427  V----ISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQH---MEGPSLIHVG----TNTEDV 475
            V    + E +            + ++I +L  E ++    +E       G    TN  ++
Sbjct: 173  VRLEVLRENEAKTKQINNIEAERVSIIRRLTEELKKKDVTIENIKRSKFGKQIPTNIPEI 232

Query: 476  N--EIAKVQEQLK---QELNDEIKDVNVKDLIE--KLKSAEEQITQLNDEIDAANKNMIK 528
            +     K  E +K   ++L D +K+   KD+ +  ++KS E  + QL +E+    KN +K
Sbjct: 233  DPQSTVKTDELMKFSVKQLQDLLKEAQTKDIEKDNRIKSYESNLLQLQNEL----KNNMK 288

Query: 529  VKSNHKLKLKQMQKTIDNF-SKVSDSNKEIVR-LTEELH----HLSQKVAELEEEKGNLQ 582
              S+ K  +++  + I NF +K +++ KE    L+ EL      L++ + +LEE +  LQ
Sbjct: 289  TISDLKQVIEEKNRIIYNFETKQTENKKESASSLSNELQATKRRLNEVLKQLEECQKQLQ 348

Query: 583  LHL---VDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHI-LQQKYD 638
              +      D    + S + +K  E++NL E+    + LL ++K ++  +    LQ+   
Sbjct: 349  TQINKPQTIDETNKLRSTIIEKDSEIQNLGES----LHLLSTEKEEIQMKYERKLQKVTT 404

Query: 639  EVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKD 698
             ++++   I++  +DQ+  ++K+ + +E I   +  K+E   + + L  +K++    +K 
Sbjct: 405  TLQNEKQKITKQLNDQIL-QLKAQYSQETIKMKNQMKEENLKLTQFLDEEKQKNKNLMKI 463

Query: 699  L-ENDKEDIMNKLQNYIQENMDLTDKLEKMSAEK--ISELLAKINHEEQSKIQTQFGIDA 755
              + +  +I+++      E++  + K+++MS E+  +   +  I    Q+   T    + 
Sbjct: 464  FNDQNPREIVDEYHYLKDESIAQSQKIKEMSEEREDLQSTILDIQKTLQNTKVTLSQKEI 523

Query: 756  KIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQE-KQKAYS 814
            +I +  L ++ + S ++ +K  +   +E    +E+R   ++    Q+ S + E K K   
Sbjct: 524  EINDMKLQMQQMTS-VNDFKEVVLEKQELEKTLEERENFIKSLQSQISSQIDECKTKLKD 582

Query: 815  EYTIQEDELVNRLAVLMDHDRVVEKQ---LLEIEHENKELQKKNQILLEENQNLQISLSD 871
            + T   + L      L + +  +++    L+++E +N+ L++K ++ LEEN  L      
Sbjct: 583  QNTKLVENLAQINTKLEERETKLQRLQSCLIDVEKQNQNLKEKLRVSLEENVKL------ 636

Query: 872  MQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTL--IVQKKKEIEDLE 929
                  + +EK N+    + E+T  +     +E N   I   HQT+  + ++K+ +  L 
Sbjct: 637  -----GSEIEKLNK----QMENTNIE-----IEVNNDAILDLHQTIDKLTKEKENLTKLN 682

Query: 930  IEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELI 989
             E   + E   +  K + +KY+K    ++Q E QL E ++ IE +    E+ +++N  LI
Sbjct: 683  DENLAEKEKMKKSLKKMEKKYDKLQSSISQKEMQLSELQDTIEKVK--TEKSSQIN-SLI 739

Query: 990  DKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESK 1049
             K V++++ Q  + TE  + ++     +++Q  +    LN+   N    +   VS  E  
Sbjct: 740  KK-VEEKENQIRE-TENTLKDMQMSQTVIEQNHQNEKQLNE---NKIKEFEKKVSKLEKI 794

Query: 1050 LAQFTTKLENMEEEMQRVSKQLLDSKQ-HNEELQILVREQDDQIKELKETKLTFEMNIPK 1108
            + +    + N++ E ++   +  + KQ    ++Q  +  Q++  K  KE++LT EM    
Sbjct: 795  VFKLKDYINNLQIEKEKYENKFKELKQIAKNQMQTSLDFQNESEKN-KESRLTSEMAF-- 851

Query: 1109 TEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTEL 1168
                 +S     +    N  +            L+ Q  E+ +Q    +Q  ++K+  + 
Sbjct: 852  ---QTLSKKYNDLQSKYNERNNAIDTLSKDLELLRNQVSEKNVQ----IQTLNSKIENQ- 903

Query: 1169 QECYTKIIQLET-LNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSA 1227
             E   +I++L+  L T +  +D  NQ+++ + K+K+ +   +++ L        + +   
Sbjct: 904  DEMKHEILKLQNKLQTFIESNDK-NQKELEETKNKVNEEKEKSEKLKLETESKENDLIQK 962

Query: 1228 VDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIV 1287
            +++    IA L +Q       +F K   EL +       K  + L  ++  ++++  K V
Sbjct: 963  INELNLTIASLTEQ-TKNPPVEFTKKMTELEL----INKKVTEDLTKIKEESEKQ--KRV 1015

Query: 1288 TMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXX 1347
               +   L++   D ++ +        D+ N +++  +  E++  A              
Sbjct: 1016 LKRENDELKSINADYKKQI-------IDLSNDVDLNGTNFENKLSAKVREIQDLKMKNEN 1068

Query: 1348 XXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTH 1407
                L     +Y++ Q++ +++ N       +++            ++++   K+L    
Sbjct: 1069 LMKTLEDLKLNYQE-QKEKLVSENASLTSKLETNQNNLNSLTTKEKQISEENKKLLTENG 1127

Query: 1408 QLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYE----KRIEDLTYE-KESELAIL 1462
            +++ K + + ++  E    L++  + F+N+  +  EY+    K+I+ L ++  + ++ I+
Sbjct: 1128 EIKNKITVLTKQNEELNDNLSKSKESFDNLNNEYQEYKRTNNKQIDGLNHQINDQKVDIM 1187

Query: 1463 RLK--MHENANHYETMQKE-SEIERVKLIEELNVKITESVSLNKQVAE--LNKALEEEVA 1517
             L   + +  N  + M++  ++   +K  E+LN K     +L ++  +  L+ A+++   
Sbjct: 1188 NLSKVIEKKQNKIQEMKEVINQSVNIKDFEKLNKKYLAVKNLYEKSEKKVLSTAIDQGTI 1247

Query: 1518 KTNEMQ---TALENQEIEIVTLNDEITNLQNMVRASSSKI 1554
            +  +M    + +E Q+ EI  L D+I N ++ +R    +I
Sbjct: 1248 REQQMSEFLSKIETQQKEIDDLKDKIQNKEDFIRKLQRQI 1287



 Score =  144 bits (348), Expect = 2e-32
 Identities = 255/1198 (21%), Positives = 526/1198 (43%), Gaps = 132/1198 (11%)

Query: 90   ISESLANTLKQKEILMEKIKQYKELSKRSSTTIVRX---XXXXXXXXXXXXXXQLGDVT- 145
            I   L   LK+K++ +E IK+ K   K+  T I                    QL D+  
Sbjct: 198  IIRRLTEELKKKDVTIENIKRSK-FGKQIPTNIPEIDPQSTVKTDELMKFSVKQLQDLLK 256

Query: 146  -------HLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQII-EAKNKATTXXX 197
                      N IK  ++ L  LQ ++K    TI DL++ I EK++II   + K T    
Sbjct: 257  EAQTKDIEKDNRIKSYESNLLQLQNELKNNMKTISDLKQVIEEKNRIIYNFETKQTENKK 316

Query: 198  XXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWK-----DEKQRLLKDIESKDVRISS 252
                              + + +++E    ++ +       DE  +L   I  KD  I +
Sbjct: 317  ESASSLSNELQATKRRLNEVLKQLEECQKQLQTQINKPQTIDETNKLRSTIIEKDSEIQN 376

Query: 253  LEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTE-IE 311
            L E+  LL   + EI +++ +  Q++                L  Q ++   +   E I+
Sbjct: 377  LGESLHLLSTEKEEIQMKYERKLQKV--TTTLQNEKQKITKQLNDQILQLKAQYSQETIK 434

Query: 312  EKGSLEIANMTELTKKIELLEHLNCQIR-----QTNKELENKLATMGTESKAVSSPSKKG 366
             K  ++  N+ +LT+ ++  +  N  +      Q  +E+ ++   +  ES A S   K+ 
Sbjct: 435  MKNQMKEENL-KLTQFLDEEKQKNKNLMKIFNDQNPREIVDEYHYLKDESIAQSQKIKEM 493

Query: 367  SPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEY 426
            S    R+  ++T   ++    Q +  TL+Q   K+I  N++ KL+M   +   D   KE 
Sbjct: 494  SE--EREDLQSTILDIQKT-LQNTKVTLSQ---KEIEINDM-KLQMQQMTSVNDF--KEV 544

Query: 427  VISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLK 486
            V+ +++            ++  I  LQ +    ++         NT+ V  +A++  +L+
Sbjct: 545  VLEKQELEKTLEE-----RENFIKSLQSQISSQIDECKTKLKDQNTKLVENLAQINTKLE 599

Query: 487  ------QELNDEIKDVNV--KDLIEKLKSAEEQITQLNDEIDAANKNM----IKVKSNHK 534
                  Q L   + DV    ++L EKL+ + E+  +L  EI+  NK M    I+++ N+ 
Sbjct: 600  ERETKLQRLQSCLIDVEKQNQNLKEKLRVSLEENVKLGSEIEKLNKQMENTNIEIEVNND 659

Query: 535  LKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMI 594
              L  + +TID   K++   + + +L +E       +AE E+ K +L+     YD    +
Sbjct: 660  AIL-DLHQTID---KLTKEKENLTKLNDE------NLAEKEKMKKSLKKMEKKYDK---L 706

Query: 595  ESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLAD--ISQL-- 650
            +S + +K +++  L +T  K  +   SQ   L++++   + +  E E+ L D  +SQ   
Sbjct: 707  QSSISQKEMQLSELQDTIEKVKTEKSSQINSLIKKVEEKENQIRETENTLKDMQMSQTVI 766

Query: 651  ----QSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDI 706
                Q+++  +E K    E+++  L     +L   I NL+++KE+     K+L   K+  
Sbjct: 767  EQNHQNEKQLNENKIKEFEKKVSKLEKIVFKLKDYINNLQIEKEKYENKFKEL---KQIA 823

Query: 707  MNKLQNYIQ-ENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIE 765
             N++Q  +  +N    +K  ++++E   + L+K  ++ QSK   +   +  I      +E
Sbjct: 824  KNQMQTSLDFQNESEKNKESRLTSEMAFQTLSKKYNDLQSKYNER---NNAIDTLSKDLE 880

Query: 766  NIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVN 825
             + +++S+   +I  L   I   ++ ++ + +  ++L ++++   K   E     +E  N
Sbjct: 881  LLRNQVSEKNVQIQTLNSKIENQDEMKHEILKLQNKLQTFIESNDKNQKEL----EETKN 936

Query: 826  RLAVLMDHDRVVEKQLLEIE-HENKELQKKNQI------LLEENQNLQISLSDMQQHYNA 878
            +   + +     EK  LE E  EN  +QK N++      L E+ +N  +  +        
Sbjct: 937  K---VNEEKEKSEKLKLETESKENDLIQKINELNLTIASLTEQTKNPPVEFTKKMTELE- 992

Query: 879  LVEKANRTDLA--ESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQI 936
            L+ K    DL   + ES K +  L+     LK I  +++  I+    +++     F  ++
Sbjct: 993  LINKKVTEDLTKIKEESEKQKRVLKRENDELKSINADYKKQIIDLSNDVDLNGTNFENKL 1052

Query: 937  ESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNI--ENLNMNVE-ELNKMNL-ELIDKH 992
             + +R+ + L  K E  ++ +  L+   QE K  +  EN ++  + E N+ NL  L  K 
Sbjct: 1053 SAKVREIQDLKMKNENLMKTLEDLKLNYQEQKEKLVSENASLTSKLETNQNNLNSLTTKE 1112

Query: 993  VQKQQTQSPDYTEQYINEI-NKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLA 1051
             Q  +      TE    EI NK+  L KQ +E    LN  ++ ++ S+ ++ ++Y+    
Sbjct: 1113 KQISEENKKLLTEN--GEIKNKITVLTKQNEE----LNDNLSKSKESFDNLNNEYQEYKR 1166

Query: 1052 QFTTKLENMEEEM--QRVS----KQLLDSKQHN-EELQILVREQDD--QIKELKETKLTF 1102
                +++ +  ++  Q+V      ++++ KQ+  +E++ ++ +  +    ++L +  L  
Sbjct: 1167 TNNKQIDGLNHQINDQKVDIMNLSKVIEKKQNKIQEMKEVINQSVNIKDFEKLNKKYLAV 1226

Query: 1103 EMNIPKTEGMIISSTI-------EPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQE-R 1154
            +    K+E  ++S+ I       + MS+  + ++             K+Q +E+FI++ +
Sbjct: 1227 KNLYEKSEKKVLSTAIDQGTIREQQMSEFLSKIETQQKEIDDLKD--KIQNKEDFIRKLQ 1284

Query: 1155 SVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDN 1212
              +     KL     + +  +I+L  L  E+       ++Q+N+  +K++ L  +  N
Sbjct: 1285 RQIATDGQKLEEITSQPFVPLIELTNLRQEMR----EKEKQLNESLAKIKFLEEKKAN 1338



 Score =  136 bits (329), Expect = 5e-30
 Identities = 200/1050 (19%), Positives = 474/1050 (45%), Gaps = 88/1050 (8%)

Query: 306  EKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKK 365
            ++TE +++ +  ++N  + TK+      LN  ++Q  +E + +L T   + + +   +K 
Sbjct: 310  KQTENKKESASSLSNELQATKR-----RLNEVLKQL-EECQKQLQTQINKPQTIDETNKL 363

Query: 366  GSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKE 425
             S +I + S      +     S    E +    ++K+ K     L+   Q + K L D+ 
Sbjct: 364  RSTIIEKDSEIQNLGESLHLLST-EKEEIQMKYERKLQK-VTTTLQNEKQKITKQLNDQI 421

Query: 426  YVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQL 485
              +  + +           ++ L    Q   ++  +  +L+ +  N ++  EI      L
Sbjct: 422  LQLKAQYSQETIKMKNQMKEENL-KLTQFLDEEKQKNKNLMKI-FNDQNPREIVDEYHYL 479

Query: 486  KQE-LNDEIKDVNVKDLIEKLKSA--EEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQK 542
            K E +    K   + +  E L+S   + Q T  N ++  + K  I++ ++ KL+++QM  
Sbjct: 480  KDESIAQSQKIKEMSEEREDLQSTILDIQKTLQNTKVTLSQKE-IEI-NDMKLQMQQMT- 536

Query: 543  TIDNFSKVSDSNKEIVRLTEELHHLSQKV-AELEEEKGNLQLHLVDYDSGRMIES--DVY 599
            ++++F +V    +E+ +  EE  +  + + +++  +    +  L D ++ +++E+   + 
Sbjct: 537  SVNDFKEVVLEKQELEKTLEERENFIKSLQSQISSQIDECKTKLKDQNT-KLVENLAQIN 595

Query: 600  KKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADIS-QLQSDQVCSE 658
             K+ E E   +     +  +E Q  +L ++L +  ++  ++  ++  ++ Q+++  +  E
Sbjct: 596  TKLEERETKLQRLQSCLIDVEKQNQNLKEKLRVSLEENVKLGSEIEKLNKQMENTNIEIE 655

Query: 659  IKS---VHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQ 715
            + +   + L + ID L+  K+ L  + +    +KE++  ++K +E   + + + +     
Sbjct: 656  VNNDAILDLHQTIDKLTKEKENLTKLNDENLAEKEKMKKSLKKMEKKYDKLQSSISQKEM 715

Query: 716  ENMDLTDKLEKMSAEK---ISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELS 772
            +  +L D +EK+  EK   I+ L+ K+  +E    +T+  +      + +  +N ++E  
Sbjct: 716  QLSELQDTIEKVKTEKSSQINSLIKKVEEKENQIRETENTLKDMQMSQTVIEQNHQNEKQ 775

Query: 773  KYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMD 832
              +++I   E+ ++ +E   + L+   D + +   EK+K  +++   +    N++   +D
Sbjct: 776  LNENKIKEFEKKVSKLEKIVFKLK---DYINNLQIEKEKYENKFKELKQIAKNQMQTSLD 832

Query: 833  HDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHY----NALVEKANRTDL 888
                 EK        NKE +  +++     Q L    +D+Q  Y    NA+   +   +L
Sbjct: 833  FQNESEK--------NKESRLTSEMAF---QTLSKKYNDLQSKYNERNNAIDTLSKDLEL 881

Query: 889  AESESTKYQTQLRDLESNLKRITH-EHQTLIVQKKKEIEDLEIEFNTQIESAIRD-KKVL 946
              ++ ++   Q++ L S ++     +H+ L +Q K +     IE N + +  + + K  +
Sbjct: 882  LRNQVSEKNVQIQTLNSKIENQDEMKHEILKLQNKLQ---TFIESNDKNQKELEETKNKV 938

Query: 947  NEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQ 1006
            NE+ EK+ +   + E++  +    I  LN+ +  L +   +       K+ T+     ++
Sbjct: 939  NEEKEKSEKLKLETESKENDLIQKINELNLTIASLTEQT-KNPPVEFTKKMTELELINKK 997

Query: 1007 YINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQR 1066
               ++ K+    +++   +   N ++ +    Y   + D  + +    T   N E ++  
Sbjct: 998  VTEDLTKIKEESEKQKRVLKRENDELKSINADYKKQIIDLSNDVDLNGT---NFENKLSA 1054

Query: 1067 VSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPK--TEGMIISSTIEPMSDD 1124
              +++ D K  NE L          +K L++ KL ++    K  +E   ++S +E   ++
Sbjct: 1055 KVREIQDLKMKNENL----------MKTLEDLKLNYQEQKEKLVSENASLTSKLETNQNN 1104

Query: 1125 ANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTE 1184
             N++             L + E  E   + +VL +Q+ +LN  L +        + LN E
Sbjct: 1105 LNSLTTKEKQISEENKKL-LTENGEIKNKITVLTKQNEELNDNLSKSKE---SFDNLNNE 1160

Query: 1185 LTGHDVVNQEQINQLKSKLEQLNTENDNL-------LSTVAELRSSISSAVDQRGFEIAE 1237
               +   N +QI+ L  ++     +  NL        + + E++  I+ +V+ + FE  +
Sbjct: 1161 YQEYKRTNNKQIDGLNHQINDQKVDIMNLSKVIEKKQNKIQEMKEVINQSVNIKDFE--K 1218

Query: 1238 LWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTME-QVTSLQ 1296
            L K++LA +   ++K+E   +V  +A +   +  +   Q S  E  +KI T + ++  L+
Sbjct: 1219 LNKKYLAVKNL-YEKSEK--KVLSTAID---QGTIREQQMS--EFLSKIETQQKEIDDLK 1270

Query: 1297 NKLQDKEEHLRNLQEKYADVINQIEILRSE 1326
            +K+Q+KE+ +R LQ + A    ++E + S+
Sbjct: 1271 DKIQNKEDFIRKLQRQIATDGQKLEEITSQ 1300



 Score =  135 bits (327), Expect = 8e-30
 Identities = 230/1158 (19%), Positives = 509/1158 (43%), Gaps = 122/1158 (10%)

Query: 477  EIAKVQEQLKQELNDEIKDVN--VKDLI-EKLKSAEEQITQLNDEIDAANKNMIKVKSNH 533
            ++  ++EQ+ Q L   + D++  V+ +I E++K+A   + Q +  I     ++++  S+ 
Sbjct: 58   QVDNMKEQI-QNLTQNLIDLSSKVEKIIPEEIKTAVPNLGQSDYVI-----SVVQHLSSL 111

Query: 534  KLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQ-LHLVDYDSGR 592
             +     Q T     K++  N+ I+   E+L       +E  + K  ++ LH  +    R
Sbjct: 112  YIAKTSSQYTSSVIQKLNSDNQSIILQNEQLK------SENSQLKATIEALHASEMQRNR 165

Query: 593  MI-ESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQ 651
             I ES+  +  +  EN A+T  K I+ +E+++  +++ L       +E++ K   I  ++
Sbjct: 166  KIQESERVRLEVLRENEAKT--KQINNIEAERVSIIRRLT------EELKKKDVTIENIK 217

Query: 652  SDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQ 711
              +   +I + ++ E ID  S  K +     E +K   +QL   +K+ +    +  N+++
Sbjct: 218  RSKFGKQIPT-NIPE-IDPQSTVKTD-----ELMKFSVKQLQDLLKEAQTKDIEKDNRIK 270

Query: 712  NYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESEL 771
            +Y    + L ++L K + + IS+L   I  EE+++I   F       +++    ++ +EL
Sbjct: 271  SYESNLLQLQNEL-KNNMKTISDLKQVI--EEKNRIIYNFETKQTENKKES-ASSLSNEL 326

Query: 772  SKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLM 831
               K R   L E +  +E+ +  L+ + ++  + + E  K  S   I++D  +  L   +
Sbjct: 327  QATKRR---LNEVLKQLEECQKQLQTQINKPQT-IDETNKLRSTI-IEKDSEIQNLGESL 381

Query: 832  DHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDM-----QQHYNALVEKANRT 886
             H    EK+ +++++E K LQK    L  E Q +   L+D       Q+    ++  N+ 
Sbjct: 382  -HLLSTEKEEIQMKYERK-LQKVTTTLQNEKQKITKQLNDQILQLKAQYSQETIKMKNQM 439

Query: 887  DLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVL 946
                 + T++  + +    NL +I ++      Q  +EI D   E++   + +I   + +
Sbjct: 440  KEENLKLTQFLDEEKQKNKNLMKIFND------QNPREIVD---EYHYLKDESIAQSQKI 490

Query: 947  NEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQ 1006
             E  E+  +    L++ + + +  ++N  +    L++  +E+ D  +Q QQ  S +  ++
Sbjct: 491  KEMSEERED----LQSTILDIQKTLQNTKVT---LSQKEIEINDMKLQMQQMTSVNDFKE 543

Query: 1007 YINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKL----AQFTTKLENMEE 1062
             + E  +L   L++++  I +L  +I++      + + D  +KL    AQ  TKLE  E 
Sbjct: 544  VVLEKQELEKTLEERENFIKSLQSQISSQIDECKTKLKDQNTKLVENLAQINTKLEERET 603

Query: 1063 EMQRVSKQLLDSKQHNEELQILVREQ-DDQIKELKET-KLTFEMNIPKTEGMIISSTIEP 1120
            ++QR+   L+D ++ N+ L+  +R   ++ +K   E  KL  +M     E  + +  I  
Sbjct: 604  KLQRLQSCLIDVEKQNQNLKEKLRVSLEENVKLGSEIEKLNKQMENTNIEIEVNNDAILD 663

Query: 1121 MSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLET 1180
            +    + +               + E+E+  +    ++++  KL + + +   K +QL  
Sbjct: 664  LHQTIDKLTKEKENLTKLNDE-NLAEKEKMKKSLKKMEKKYDKLQSSISQ---KEMQLSE 719

Query: 1181 LNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWK 1240
            L   +         QIN L  K+E+   +     +T+ +++ S  + ++Q      +L +
Sbjct: 720  LQDTIEKVKTEKSSQINSLIKKVEEKENQIRETENTLKDMQMS-QTVIEQNHQNEKQLNE 778

Query: 1241 QHLAQREADFQKTE----------HELRVQLSAFESKYEQLL----DSVQSSTQEETNKI 1286
              + + E    K E          + L+++   +E+K+++L     + +Q+S   +    
Sbjct: 779  NKIKEFEKKVSKLEKIVFKLKDYINNLQIEKEKYENKFKELKQIAKNQMQTSLDFQNESE 838

Query: 1287 VTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQI-------EILRSEIEDEKVAFXXXXX 1339
               E   + +   Q   +   +LQ KY +  N I       E+LR+++ ++ V       
Sbjct: 839  KNKESRLTSEMAFQTLSKKYNDLQSKYNERNNAIDTLSKDLELLRNQVSEKNVQIQTLNS 898

Query: 1340 XXXXXXXXXXXDLRTENQ----------SYKQMQEQSILNINEENAQLKKSSXXXXXXXX 1389
                        L+ +N+          + K+++E     +NEE  + +K          
Sbjct: 899  KIENQDEMKHEILKLQNKLQTFIESNDKNQKELEETKN-KVNEEKEKSEKLKLETESKEN 957

Query: 1390 XXXXRVNDAEAKVLELTHQLELKDSEIYQKTHE-------YTITLTQRNDEFENVRQQLV 1442
                ++N+    +  LT Q +    E  +K  E        T  LT+  +E E  ++ L 
Sbjct: 958  DLIQKINELNLTIASLTEQTKNPPVEFTKKMTELELINKKVTEDLTKIKEESEKQKRVLK 1017

Query: 1443 EYEKRIEDLTYEKESELAILRLKMHENANHYET--MQKESEIERVKLIEELNVKITESVS 1500
                 ++ +  + + ++  L   +  N  ++E     K  EI+ +K+  E  +K  E + 
Sbjct: 1018 RENDELKSINADYKKQIIDLSNDVDLNGTNFENKLSAKVREIQDLKMKNENLMKTLEDLK 1077

Query: 1501 LNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSF 1560
            LN Q  +  K + E  + T++++T  +N    + T   +I+     +   + +I+  ++ 
Sbjct: 1078 LNYQ-EQKEKLVSENASLTSKLETN-QNNLNSLTTKEKQISEENKKLLTENGEIKNKITV 1135

Query: 1561 ASDTKQGRDEQLDNTMNK 1578
               TKQ  +E+L++ ++K
Sbjct: 1136 L--TKQ--NEELNDNLSK 1149



 Score =  135 bits (326), Expect = 1e-29
 Identities = 236/1122 (21%), Positives = 504/1122 (44%), Gaps = 152/1122 (13%)

Query: 228  MEAEWKDEKQRLLKDIESKDVRISSLEEA--NKLLEAARFEISLEHSKLAQELEQXXXXX 285
            +EAE     +RL ++++ KDV I +++ +   K +     EI  + +    EL +     
Sbjct: 191  IEAERVSIIRRLTEELKKKDVTIENIKRSKFGKQIPTNIPEIDPQSTVKTDELMK----- 245

Query: 286  XXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKEL 345
                     L K++     E+   I+   S  +    EL   ++ +  L   I + N+ +
Sbjct: 246  -FSVKQLQDLLKEAQTKDIEKDNRIKSYESNLLQLQNELKNNMKTISDLKQVIEEKNRII 304

Query: 346  ENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINK- 404
             N   T  TE+K  S+ S       +++       +++    QL ++     T  + NK 
Sbjct: 305  YN-FETKQTENKKESASSLSNELQATKRRLNEVLKQLEECQKQLQTQINKPQTIDETNKL 363

Query: 405  -NEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGP 463
             + I + +  IQ+L + L     + +EK+                  ++Q+++++ ++  
Sbjct: 364  RSTIIEKDSEIQNLGESL---HLLSTEKE------------------EIQMKYERKLQ-- 400

Query: 464  SLIHVGTNTEDVNEIAKVQEQLKQ---ELNDEIKDVNVKDLIEKLKSAEEQITQLNDEID 520
                V T  +  NE  K+ +QL     +L  +     +K +  ++K    ++TQ  DE  
Sbjct: 401  ---KVTTTLQ--NEKQKITKQLNDQILQLKAQYSQETIK-MKNQMKEENLKLTQFLDEEK 454

Query: 521  AANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGN 580
              NKN++K+ ++     +  ++ +D +  + D  + I +        SQK+ E+ EE+ +
Sbjct: 455  QKNKNLMKIFND-----QNPREIVDEYHYLKD--ESIAQ--------SQKIKEMSEERED 499

Query: 581  LQLHLVDYDSG-RMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDE 639
            LQ  ++D     +  +  + +K IE+ ++ + +++ ++ +   K ++V E   L++  +E
Sbjct: 500  LQSTILDIQKTLQNTKVTLSQKEIEINDM-KLQMQQMTSVNDFK-EVVLEKQELEKTLEE 557

Query: 640  VEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDL 699
             E+ +  +    S Q+  E K+  L++Q   L  +  ++   +E  +   ++L   + D+
Sbjct: 558  RENFIKSLQSQISSQI-DECKT-KLKDQNTKLVENLAQINTKLEERETKLQRLQSCLIDV 615

Query: 700  ENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQE 759
            E   +++  KL+  ++EN+ L  ++EK++ +            E + I+ +   DA +  
Sbjct: 616  EKQNQNLKEKLRVSLEENVKLGSEIEKLNKQM-----------ENTNIEIEVNNDAIL-- 662

Query: 760  RDLYIENIESELSKYKSRICRL-EESIAVMEDRRYSL---ERKADQLGSYLQEKQKAYSE 815
             DL+ + I+ +L+K K  + +L +E++A  E  + SL   E+K D+L S + +K+   SE
Sbjct: 663  -DLH-QTID-KLTKEKENLTKLNDENLAEKEKMKKSLKKMEKKYDKLQSSISQKEMQLSE 719

Query: 816  Y--TIQ--EDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSD 871
               TI+  + E  +++  L+      E Q+ E E+  K++Q    ++ + +QN +    +
Sbjct: 720  LQDTIEKVKTEKSSQINSLIKKVEEKENQIRETENTLKDMQMSQTVIEQNHQNEKQLNEN 779

Query: 872  MQQHYNALVEKANR--------TDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKK 923
              + +   V K  +         +  + E  KY+ + ++L+   K   ++ QT +  + +
Sbjct: 780  KIKEFEKKVSKLEKIVFKLKDYINNLQIEKEKYENKFKELKQIAK---NQMQTSLDFQNE 836

Query: 924  EIEDLEIEFNTQIESAIRDKKV--LNEKY-EKN--IEYVTQ----LEAQLQEYKNNIENL 974
              ++ E    +++      KK   L  KY E+N  I+ +++    L  Q+ E    I+ L
Sbjct: 837  SEKNKESRLTSEMAFQTLSKKYNDLQSKYNERNNAIDTLSKDLELLRNQVSEKNVQIQTL 896

Query: 975  NMNVEELNKMNLELIDKHVQKQQT--QSPDYTEQYINEI-NKLNALLKQKDEEIIA---- 1027
            N  +E  ++M  E++ K   K QT  +S D  ++ + E  NK+N   K+K E++      
Sbjct: 897  NSKIENQDEMKHEIL-KLQNKLQTFIESNDKNQKELEETKNKVNE-EKEKSEKLKLETES 954

Query: 1028 ----LNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQI 1083
                L QKIN   ++  S+    ++   +FT K+  +E   ++V++ L   K+ +E+ + 
Sbjct: 955  KENDLIQKINELNLTIASLTEQTKNPPVEFTKKMTELELINKKVTEDLTKIKEESEKQKR 1014

Query: 1084 LVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLK 1143
            +++ ++D   ELK     ++  I                D +N+VD             K
Sbjct: 1015 VLKREND---ELKSINADYKKQI---------------IDLSNDVDLNGTNFENKLSA-K 1055

Query: 1144 VQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKL 1203
            V+E ++   +   L +    L    QE   K++   + N  LT     NQ  +N L +K 
Sbjct: 1056 VREIQDLKMKNENLMKTLEDLKLNYQEQKEKLV---SENASLTSKLETNQNNLNSLTTKE 1112

Query: 1204 EQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSA 1263
            +Q++ EN  LL+   E+++ I+    Q      E    +L++ +  F    +E +     
Sbjct: 1113 KQISEENKKLLTENGEIKNKITVLTKQN-----EELNDNLSKSKESFDNLNNEYQ----E 1163

Query: 1264 FESKYEQLLDSVQSSTQEETNKIVTMEQV-TSLQNKLQDKEE 1304
            ++    + +D +     ++   I+ + +V    QNK+Q+ +E
Sbjct: 1164 YKRTNNKQIDGLNHQINDQKVDIMNLSKVIEKKQNKIQEMKE 1205



 Score =  125 bits (302), Expect = 9e-27
 Identities = 184/917 (20%), Positives = 377/917 (41%), Gaps = 80/917 (8%)

Query: 669  DALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMS 728
            D++S S         N  L+ E L   IK+     +++  ++QN  Q  +DL+ K+EK+ 
Sbjct: 28   DSVSLSSIHETKNKRNQVLEYEML---IKNSNMQVDNMKEQIQNLTQNLIDLSSKVEKII 84

Query: 729  AEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVM 788
             E+I   +  +        Q+ + I        LYI    S+ +    +    +    ++
Sbjct: 85   PEEIKTAVPNLG-------QSDYVISVVQHLSSLYIAKTSSQYTSSVIQKLNSDNQSIIL 137

Query: 789  EDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHEN 848
            ++ +   E    +         +      IQE E V RL VL +++    KQ+  IE E 
Sbjct: 138  QNEQLKSENSQLKATIEALHASEMQRNRKIQESERV-RLEVLRENEAKT-KQINNIEAER 195

Query: 849  KELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLK 908
              + ++   L EE +   +++ ++++         N  ++    + K    ++     L+
Sbjct: 196  VSIIRR---LTEELKKKDVTIENIKRSKFGKQIPTNIPEIDPQSTVKTDELMKFSVKQLQ 252

Query: 909  RITHEHQTLIVQKKKEIEDLE---IEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQ 965
             +  E QT  ++K   I+  E   ++   ++++ ++    L +  E+    +   E +  
Sbjct: 253  DLLKEAQTKDIEKDNRIKSYESNLLQLQNELKNNMKTISDLKQVIEEKNRIIYNFETKQT 312

Query: 966  EYKNNIENLNMNVEELNKMNLELIDKHVQK--QQTQSPDYTEQYINEINKLNALLKQKDE 1023
            E K    +   N  +  K  L  + K +++  +Q Q+     Q I+E NKL + + +KD 
Sbjct: 313  ENKKESASSLSNELQATKRRLNEVLKQLEECQKQLQTQINKPQTIDETNKLRSTIIEKDS 372

Query: 1024 EIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQI 1083
            EI  L + ++        +   YE KL + TT L+N   E Q+++KQL D     + LQ+
Sbjct: 373  EIQNLGESLHLLSTEKEEIQMKYERKLQKVTTTLQN---EKQKITKQLND-----QILQL 424

Query: 1084 LVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLK 1143
              +   + IK   + K   E N+  T+ +          D+    +             +
Sbjct: 425  KAQYSQETIKMKNQMK---EENLKLTQFL----------DEEKQKNKNLMKIFNDQNPRE 471

Query: 1144 VQEEEEFIQERSVLQEQSAK-LNTELQECYTKIIQLE-TL-NTELTGHDVVNQEQINQLK 1200
            + +E  ++++ S+ Q Q  K ++ E ++  + I+ ++ TL NT++T      + +IN +K
Sbjct: 472  IVDEYHYLKDESIAQSQKIKEMSEEREDLQSTILDIQKTLQNTKVTLSQ--KEIEINDMK 529

Query: 1201 SKLEQLNTEND---------NLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQ 1251
             +++Q+ + ND          L  T+ E  + I S   Q   +I E  K  L  +     
Sbjct: 530  LQMQQMTSVNDFKEVVLEKQELEKTLEERENFIKSLQSQISSQIDEC-KTKLKDQNTKLV 588

Query: 1252 KTEHELRVQLSAFESKYEQL---LDSVQSSTQEETNKI-VTMEQVTSLQNKLQDKEEHLR 1307
            +   ++  +L   E+K ++L   L  V+   Q    K+ V++E+   L ++++   + + 
Sbjct: 589  ENLAQINTKLEERETKLQRLQSCLIDVEKQNQNLKEKLRVSLEENVKLGSEIEKLNKQME 648

Query: 1308 NLQ---EKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQE 1364
            N     E   D I  +     ++  EK                    L+   + Y ++Q 
Sbjct: 649  NTNIEIEVNNDAILDLHQTIDKLTKEKENLTKLNDENLAEKEKMKKSLKKMEKKYDKLQS 708

Query: 1365 QSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYT 1424
                +I+++  QL +              ++N    KV E  +Q+   ++ +       T
Sbjct: 709  ----SISQKEMQLSELQDTIEKVKTEKSSQINSLIKKVEEKENQIRETENTLKDMQMSQT 764

Query: 1425 ITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIER 1484
            +      +E +    ++ E+EK++  L      E  + +LK + N    E  + E++ + 
Sbjct: 765  VIEQNHQNEKQLNENKIKEFEKKVSKL------EKIVFKLKDYINNLQIEKEKYENKFKE 818

Query: 1485 VKLIEELNVKITESVSLNKQVAELNKALEEEVA------KTNEMQTALENQEIEIVTLND 1538
            +K I + N   T     N+        L  E+A      K N++Q+    +   I TL+ 
Sbjct: 819  LKQIAK-NQMQTSLDFQNESEKNKESRLTSEMAFQTLSKKYNDLQSKYNERNNAIDTLSK 877

Query: 1539 EITNLQNMVRASSSKIQ 1555
            ++  L+N V   + +IQ
Sbjct: 878  DLELLRNQVSEKNVQIQ 894



 Score =  110 bits (265), Expect = 3e-22
 Identities = 179/872 (20%), Positives = 387/872 (44%), Gaps = 85/872 (9%)

Query: 235  EKQRLLKDIESKDVRISSLE-EANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXX 293
            EKQ L K +E ++  I SL+ + +  ++  + ++  +++KL + L Q             
Sbjct: 547  EKQELEKTLEERENFIKSLQSQISSQIDECKTKLKDQNTKLVENLAQINTKLEERETKLQ 606

Query: 294  XLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMG 353
             L    I+   ++   ++EK  + +    +L  +IE    LN Q+  TN E+E       
Sbjct: 607  RLQSCLIDVE-KQNQNLKEKLRVSLEENVKLGSEIE---KLNKQMENTNIEIE------- 655

Query: 354  TESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMV 413
                           ++      +  +K K   ++L+ E L    +K+  K  + K+E  
Sbjct: 656  ----------VNNDAILDLHQTIDKLTKEKENLTKLNDENL---AEKEKMKKSLKKMEKK 702

Query: 414  IQSLNKDLVDKEYVISE-KDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNT 472
               L   +  KE  +SE +DT            ++LI +++ +  Q  E  + +      
Sbjct: 703  YDKLQSSISQKEMQLSELQDTIEKVKTEKSSQINSLIKKVEEKENQIRETENTL------ 756

Query: 473  EDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSN 532
            +D+     V EQ  Q    ++ +  +K+  +K+   E+ + +L D I+  N  + K K  
Sbjct: 757  KDMQMSQTVIEQNHQN-EKQLNENKIKEFEKKVSKLEKIVFKLKDYIN--NLQIEKEKYE 813

Query: 533  HKLK-LKQMQK----TIDNFSKVSDSNKEIVRLTEEL--HHLSQKVAELEEEKGNLQLHL 585
            +K K LKQ+ K    T  +F   S+ NKE  RLT E+    LS+K  +L+  K N + + 
Sbjct: 814  NKFKELKQIAKNQMQTSLDFQNESEKNKES-RLTSEMAFQTLSKKYNDLQS-KYNERNNA 871

Query: 586  VDYDSG--RMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDK 643
            +D  S    ++ + V +K ++++ L  ++++    ++ +   L  +L    +  D+ + +
Sbjct: 872  IDTLSKDLELLRNQVSEKNVQIQTL-NSKIENQDEMKHEILKLQNKLQTFIESNDKNQKE 930

Query: 644  LADI-SQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLEND 702
            L +  +++  ++  SE   +  E + + L     EL L I +L           +  +N 
Sbjct: 931  LEETKNKVNEEKEKSEKLKLETESKENDLIQKINELNLTIASLT----------EQTKNP 980

Query: 703  KEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDL 762
              +   K+      N  +T+ L K+  E  SE   ++   E  ++++    D K Q  DL
Sbjct: 981  PVEFTKKMTELELINKKVTEDLTKIKEE--SEKQKRVLKRENDELKS-INADYKKQIIDL 1037

Query: 763  YIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLG-SYLQEKQKAYSEYTIQED 821
               +++   + +++++      I  ++ +  +L +  + L  +Y ++K+K  SE      
Sbjct: 1038 S-NDVDLNGTNFENKLSAKVREIQDLKMKNENLMKTLEDLKLNYQEQKEKLVSENASLTS 1096

Query: 822  ELV---NRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNA 878
            +L    N L  L   ++ + ++  ++  EN E++ K  +L ++N+ L  +LS  ++ ++ 
Sbjct: 1097 KLETNQNNLNSLTTKEKQISEENKKLLTENGEIKNKITVLTKQNEELNDNLSKSKESFDN 1156

Query: 879  L---VEKANRTDLAESESTKYQTQLRDLE-SNLKRITHEHQTLIVQKKKEI-EDLEIEFN 933
            L    ++  RT+  + +   +Q   + ++  NL ++  + Q  I + K+ I + + I+  
Sbjct: 1157 LNNEYQEYKRTNNKQIDGLNHQINDQKVDIMNLSKVIEKKQNKIQEMKEVINQSVNIKDF 1216

Query: 934  TQIESAIRDKKVLNEKYEKN-----IEYVTQLEAQLQEYKNNIENLNMNVEELNK--MNL 986
             ++       K L EK EK      I+  T  E Q+ E+ + IE     +++L     N 
Sbjct: 1217 EKLNKKYLAVKNLYEKSEKKVLSTAIDQGTIREQQMSEFLSKIETQQKEIDDLKDKIQNK 1276

Query: 987  ELIDKHVQKQQTQSPDYTEQYIN-------EINKLNALLKQKDEEIIALNQKINNAQVSY 1039
            E   + +Q+Q        E+  +       E+  L   +++K++++     KI   +   
Sbjct: 1277 EDFIRKLQRQIATDGQKLEEITSQPFVPLIELTNLRQEMREKEKQLNESLAKIKFLEEKK 1336

Query: 1040 MSMVSDYESKLAQFTTKLENMEEEMQRVSKQL 1071
             +  +DYE + A+F  + ++++E +  ++K++
Sbjct: 1337 ANDKADYEVEKARFDKERKSLKELVDMMAKKV 1368


>UniRef50_A2DNX6 Cluster: Viral A-type inclusion protein, putative;
            n=1; Trichomonas vaginalis G3|Rep: Viral A-type inclusion
            protein, putative - Trichomonas vaginalis G3
          Length = 2923

 Score =  158 bits (384), Expect = 1e-36
 Identities = 286/1529 (18%), Positives = 638/1529 (41%), Gaps = 134/1529 (8%)

Query: 149  NTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXX 208
            NTIK+  N L+ ++  ++    TI DL+E++    +  E +                   
Sbjct: 1352 NTIKQSKNELTNVRNDLQKANLTINDLEEEMENMRKKNEQQETILQDAQKMVDQLNKQIL 1411

Query: 209  XXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANK-LLEAARFEI 267
                  ++  TK +      E   K+++  + K+ E+K ++I +  E NK  LE    ++
Sbjct: 1412 ALKMQNEENETKFKSTIDETENSNKNKELTIRKEYEAKIIQIQTDNEENKSKLEKKYSDL 1471

Query: 268  SLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIE----EKGSLEIANMTE 323
              +     +E E                  ++++ S + +TE      EK   EI N+ +
Sbjct: 1472 KNDFENNLKEKETAIMRIQREQKKLTNKMAKALKES-DSRTESVYNELEKSHTEIENLKQ 1530

Query: 324  -LTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKM 382
             LT+    ++ L   +  T  +  ++      + K +     + +  IS         K 
Sbjct: 1531 KLTESETKVKSLENSLSMTQSQYNDEQTETSNKHKQMKKTILELNQTISNLETEKIQLKS 1590

Query: 383  KSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXX 442
             +  S    + L+   ++   KN  +K +++   LNK++ D + +I++ +          
Sbjct: 1591 NNESSNDRIKRLSTALEQISKKNNESKEDII--KLNKEIKDAKEIINKLNEQIEDKDDEI 1648

Query: 443  XGKDTLIAQLQLEHQQHMEGPSLI-----HVGTNTEDVNEIAKVQEQLKQELNDEIKDVN 497
                 L  + + +  Q  +   +I      +     +++E+  V+ +L+  L+D  K+ N
Sbjct: 1649 NQLKRLQDRYEQQKNQLSQSNEMILKLHDEISEKDRELSEMKSVKRRLQVALDDLDKERN 1708

Query: 498  VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEI 557
                IE+L   + ++ Q N+ +   N    +   N + +L Q +    N  K      EI
Sbjct: 1709 E---IEELHQTQNELKQQNNLLQKENFVKTETIKNLEDELSQTKSHATNLIKTVSEKTEI 1765

Query: 558  VRLTEELHHLSQKVAELEEE-----KGNLQ-----LHLVDYD-SGRMIESDVYKKMIE-- 604
               T++ +    K  + +EE     K  ++     L+ ++   + ++ E++  KK I   
Sbjct: 1766 YNSTKQDNDEKDKTIKSQEEIIDKLKNEIKEKTSTLNQINSKFNDKVEENETLKKQISSA 1825

Query: 605  MENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVC----SEIK 660
             +N  E   +  S+    K    Q++    + Y +++++ +++ +   +QV     SE K
Sbjct: 1826 KQNNEELERRLDSMFSKVKL-FEQQIQDNTKNYQKIDEEKSNLQKTLRNQVVLLDESETK 1884

Query: 661  SVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKD------LENDK-----EDIMNK 709
               LE + + +  + + L     +L+   ++L    +D       EN+K     +D++NK
Sbjct: 1885 KHELEIKFNTMKTNFENLQKQFNDLQTKHDELKKENEDQIENLSKENEKFDRNSKDLINK 1944

Query: 710  LQNYIQENMDL-----TDKLE----KMSAEKISELLAKINHEEQSKIQTQFGI-DAKIQE 759
            +     EN  L     T KLE    K S + + E+  K+++E   K +T+  + + K Q 
Sbjct: 1945 ITQLESENRQLGGDLQTTKLELEDIKRSKQNLQEIYDKVSNE---KSETEKSVRELKKQN 2001

Query: 760  RDL--YIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQ-LGSY--LQEKQ-KAY 813
            +DL   +E+I  + +    +I  +   +  +++ +  LE    + L  Y  L+EK  K  
Sbjct: 2002 KDLLGQLEDITEKETSANGKISSINSQMKTLKEEKDKLESSNFKLLEDYRTLKEKSIKEI 2061

Query: 814  SEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDM- 872
            +E  IQ D+L N    L +    +EK L   E++     +    L   N +L+ ++S+M 
Sbjct: 2062 NEIKIQNDKLTNENTTLKNEIERIEKSL---ENQKSVNSQNISALTTRNNDLERTISEMR 2118

Query: 873  QQHYNALV---EKANRTDLAESESTKYQTQLRDLE---SNLKRITHEHQTLIVQKKKEIE 926
            QQH  ++    E     ++++ E    +   ++L+    NL +  +E +  I ++K E +
Sbjct: 2119 QQHMKSISTIGEMTTNDEISKREIRNLKENNKNLQEKIDNLIKNENELKRQISKEKSEKD 2178

Query: 927  DLEIEFNTQIESAIRD----KKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVE-EL 981
              + ++  +     R        +N+  ++N + V+Q+E +L+  KN  +++N N+E E+
Sbjct: 2179 QQKSQYENEDHENKRKISELSNQINQLSQENKDLVSQIE-ELKSSKNKSKDINKNLEKEI 2237

Query: 982  NKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMS 1041
            +++ +E  +   +K +  +  Y+ +   ++  +    + + ++II  +        S   
Sbjct: 2238 DRLRIE--NSQNEKLRISAEKYSAELETKLESIENKHETEKKDIIDRHFAAEQELDSQRI 2295

Query: 1042 MVSDYESKLAQFTTKLENMEEEMQRVS--KQLLDSKQHNEELQILVREQDDQIKELKET- 1098
             +S+ E ++  +    + + +    VS  K  +D K        ++ +Q  QI +L  T 
Sbjct: 2296 KISNLEQEIEHYKAVEDELRKRQLTVSPTKSKIDDKNSK-----IIEDQTKQISDLHNTI 2350

Query: 1099 -KLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVL 1157
             ++    ++ ++E   + S++       N++             L  +++ E + + + L
Sbjct: 2351 SRMAERFSVVESE---LKSSLSREKTLRNDI----LEIKSESRKLLSEKQNELLSKTNEL 2403

Query: 1158 QEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTV 1217
             ++  +L  ++ E   K  ++E L  +L      N + I  L  ++   NT  D L S +
Sbjct: 2404 SKKDNELMVKVSEISQKQNEIEILKEQLNNMSKTNDKTIEDLTKQILDKNTTIDQLKSKL 2463

Query: 1218 AELRSSISSAVDQ-RGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQ 1276
             +L    S+  DQ +  +  E   Q L+    + + T +ELR Q    E  + Q+L+  +
Sbjct: 2464 IDL----STKSDQSQTIQDLENKLQTLSISTKEKEGTINELRQQ---NEQLHLQILEK-E 2515

Query: 1277 SSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAF-X 1335
            S+ + E  K+  + +V S   ++Q K  +  N++    + INQIE L  E++  K +F  
Sbjct: 2516 SNIRSEKAKVNHLNEVIS---EIQIKNNN--NVKNNNQEYINQIEQLSRELDSTKRSFIT 2570

Query: 1336 XXXXXXXXXXXXXXXDLRTE-NQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXR 1394
                           ++R E +++  +  E+ +L +  E   L KS+             
Sbjct: 2571 TSNEKNELEKSYHLLEIRLERSETTNKKYEEQVLRMTSEIDDLHKSNDEKQLSIERLNRE 2630

Query: 1395 VNDAEAKVLELTHQLE-----LKD--------SEIYQKTHEYTITLTQRNDEFENVRQQL 1441
            +   +++ + +  +LE     L D          + ++  +   +L Q      +++  L
Sbjct: 2631 LRSLKSQHISIKTELEETRHLLSDKATTESENDRLKEENEKLQHSLHQTKTSINSMQTNL 2690

Query: 1442 VEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSL 1501
             + E+  + +  EK  ++   +L   +  N  +  +++ E E   + E + +     +  
Sbjct: 2691 TKIER--DMIPKEKYQDILQSKLYYEQEYNKLKETKQQIENEYRNIDERIRIVHDFIIHY 2748

Query: 1502 NKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFA 1561
            N +V ++ K +   +     + +  + +EI    L ++ T +   ++ +S  +   +   
Sbjct: 2749 NYKVGDIRKYVSALIGYLQPLFSIFKYREINF-PLFEKTTKI---LKIASPSLVASIDGN 2804

Query: 1562 SDTKQGRDEQLDNTMNKELLDAVPRAELD 1590
                  ++ QL +T+  EL        +D
Sbjct: 2805 KSILGSQETQLLSTVRDELFSITHGGGID 2833



 Score =  156 bits (378), Expect = 5e-36
 Identities = 282/1484 (19%), Positives = 643/1484 (43%), Gaps = 145/1484 (9%)

Query: 212  EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271
            E  K+ ++ +Q+    +  +         ++I+ KD+  SSL+   K +   + E  L  
Sbjct: 1154 EKMKRDISDLQDTMTTLTTQ----NSEFAREIKDKDLENSSLQYQIKAISDEQNESVLAQ 1209

Query: 272  SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELL 331
            ++  ++ +                 K  +E + +   E++ K     + + ELT ++   
Sbjct: 1210 NEQNKKRDLLIAKKQNKIVKLENRMKDLLEKTTKSLQEMDNKNKTLNSKVAELTNELSKS 1269

Query: 332  EHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSS 391
            +    +I + N E  + L     E K++    K      S+     T    +    QL+ 
Sbjct: 1270 KE---EIDKLNNEKSSIL-----EEKSILETEK------SKIEQEKTVILQEKTELQLNF 1315

Query: 392  E-TLNQ-DTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLI 449
            E T NQ    K +++ E  +L+ +I+  N  L+++E  I +               +  I
Sbjct: 1316 EQTTNQTQLQKDLSQKEFERLQSIIEEKNISLLEQENTIKQSKNELTNVRNDLQKANLTI 1375

Query: 450  AQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQ-LKQELNDEIKDVNVKDLIEKLKSA 508
              L+ E  ++M   +        +    + ++ +Q L  ++ +E  +   K  I++ +++
Sbjct: 1376 NDLE-EEMENMRKKNEQQETILQDAQKMVDQLNKQILALKMQNEENETKFKSTIDETENS 1434

Query: 509  EE--QITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKE--IVRLTEEL 564
             +  ++T +  E +A    +      +K KL++    + N  + +   KE  I+R+  E 
Sbjct: 1435 NKNKELT-IRKEYEAKIIQIQTDNEENKSKLEKKYSDLKNDFENNLKEKETAIMRIQREQ 1493

Query: 565  HHLSQKVAE-LEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQK 623
              L+ K+A+ L+E     +    + +       ++ +K+ E E   ++   ++S+ +SQ 
Sbjct: 1494 KKLTNKMAKALKESDSRTESVYNELEKSHTEIENLKQKLTESETKVKSLENSLSMTQSQY 1553

Query: 624  FDLVQELHILQQKYDEVEDKLAD-ISQLQSDQVCSEIKSVHLEEQIDALSA-----SKKE 677
             D   E     ++  +   +L   IS L+++++  +  +    ++I  LS      SKK 
Sbjct: 1554 NDEQTETSNKHKQMKKTILELNQTISNLETEKIQLKSNNESSNDRIKRLSTALEQISKKN 1613

Query: 678  LALVIENLKLDKE-----QLYGTIKDLENDKEDIMNKLQN----YIQENMDLTDKLEKMS 728
                 + +KL+KE     ++   + +   DK+D +N+L+     Y Q+   L+   E + 
Sbjct: 1614 NESKEDIIKLNKEIKDAKEIINKLNEQIEDKDDEINQLKRLQDRYEQQKNQLSQSNEMIL 1673

Query: 729  A--EKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIA 786
               ++ISE   +++  +  K + Q  +D   +ER+  IE +    ++ K +   L++   
Sbjct: 1674 KLHDEISEKDRELSEMKSVKRRLQVALDDLDKERN-EIEELHQTQNELKQQNNLLQKENF 1732

Query: 787  VMEDRRYSLERKADQLGSYLQEKQKAYSE----YTIQEDELVNRLAVLMDHDRVVEKQLL 842
            V  +   +LE +  Q  S+     K  SE    Y   + +   +   +   + +++K   
Sbjct: 1733 VKTETIKNLEDELSQTKSHATNLIKTVSEKTEIYNSTKQDNDEKDKTIKSQEEIIDKLKN 1792

Query: 843  EIEHENKELQKKNQIL---LEENQNLQISLSDMQQHYNALVEKAN----RTDLAESE--- 892
            EI+ +   L + N      +EEN+ L+  +S  +Q+   L  + +    +  L E +   
Sbjct: 1793 EIKEKTSTLNQINSKFNDKVEENETLKKQISSAKQNNEELERRLDSMFSKVKLFEQQIQD 1852

Query: 893  STKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNT------------------ 934
            +TK   ++ + +SNL++       L+ + + +  +LEI+FNT                  
Sbjct: 1853 NTKNYQKIDEEKSNLQKTLRNQVVLLDESETKKHELEIKFNTMKTNFENLQKQFNDLQTK 1912

Query: 935  ------QIESAIRDKKVLNEKYEKN----IEYVTQLEAQLQEYKNNIENLNMNVEEL--N 982
                  + E  I +    NEK+++N    I  +TQLE++ ++   +++   + +E++  +
Sbjct: 1913 HDELKKENEDQIENLSKENEKFDRNSKDLINKITQLESENRQLGGDLQTTKLELEDIKRS 1972

Query: 983  KMNLELIDKHVQKQQTQSPDYTEQYINEINKLNA-LLKQKD---EEIIALNQKINNAQVS 1038
            K NL+ I   V  ++++    TE+ + E+ K N  LL Q +   E+  + N KI++   S
Sbjct: 1973 KQNLQEIYDKVSNEKSE----TEKSVRELKKQNKDLLGQLEDITEKETSANGKISSIN-S 2027

Query: 1039 YMSMVSDYESKLAQFTTK-LENMEEEMQRVSKQLLDSKQHNEEL---QILVREQDDQI-K 1093
             M  + + + KL     K LE+     ++  K++ + K  N++L      ++ + ++I K
Sbjct: 2028 QMKTLKEEKDKLESSNFKLLEDYRTLKEKSIKEINEIKIQNDKLTNENTTLKNEIERIEK 2087

Query: 1094 ELKETKLTFEMNIP--KTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFI 1151
             L+  K     NI    T    +  TI  M    +               +  +E     
Sbjct: 2088 SLENQKSVNSQNISALTTRNNDLERTISEMRQQ-HMKSISTIGEMTTNDEISKREIRNLK 2146

Query: 1152 QERSVLQEQSAKL---NTELQECYTK-IIQLETLNTELTGHDVVNQEQINQLKSKLEQLN 1207
            +    LQE+   L     EL+   +K   + +   ++    D  N+ +I++L +++ QL+
Sbjct: 2147 ENNKNLQEKIDNLIKNENELKRQISKEKSEKDQQKSQYENEDHENKRKISELSNQINQLS 2206

Query: 1208 TENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESK 1267
             EN +L+S + EL+SS + + D     I +  ++ + +   +  + E +LR+    + ++
Sbjct: 2207 QENKDLVSQIEELKSSKNKSKD-----INKNLEKEIDRLRIENSQNE-KLRISAEKYSAE 2260

Query: 1268 YEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQ---EKYADVINQIEILR 1324
             E  L+S+++  + ET K   +++  + + +L  +   + NL+   E Y  V +++   +
Sbjct: 2261 LETKLESIEN--KHETEKKDIIDRHFAAEQELDSQRIKISNLEQEIEHYKAVEDELRKRQ 2318

Query: 1325 SEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXX 1384
              +   K                   DL   N   +  +  S++    +++  ++ +   
Sbjct: 2319 LTVSPTKSKIDDKNSKIIEDQTKQISDL--HNTISRMAERFSVVESELKSSLSREKTLRN 2376

Query: 1385 XXXXXXXXXR--VNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLV 1442
                     R  +++ + ++L  T++L  KD+E+  K  E    ++Q+ +E E +++QL 
Sbjct: 2377 DILEIKSESRKLLSEKQNELLSKTNELSKKDNELMVKVSE----ISQKQNEIEILKEQLN 2432

Query: 1443 EY----EKRIEDLT---YEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKI 1495
                  +K IEDLT    +K + +  L+ K+ + +   +  Q   ++E    ++ L++  
Sbjct: 2433 NMSKTNDKTIEDLTKQILDKNTTIDQLKSKLIDLSTKSDQSQTIQDLE--NKLQTLSIST 2490

Query: 1496 TESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQ 1555
             E      ++ + N+ L  ++    E ++ + +++ ++  LN+ I+ +Q  ++ +++   
Sbjct: 2491 KEKEGTINELRQQNEQLHLQIL---EKESNIRSEKAKVNHLNEVISEIQ--IKNNNNVKN 2545

Query: 1556 KHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDLAMYMLHQR 1599
             +  + +  +Q    +LD+T    +  +  + EL+ + ++L  R
Sbjct: 2546 NNQEYINQIEQ-LSRELDSTKRSFITTSNEKNELEKSYHLLEIR 2588



 Score =  154 bits (374), Expect = 2e-35
 Identities = 224/1019 (21%), Positives = 440/1019 (43%), Gaps = 91/1019 (8%)

Query: 141  LGDVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKI-NEKDQIIEAKNKATTXXXXX 199
            L D+    N I+E     + L+ +  +++       E I N +D++ + K+ AT      
Sbjct: 1700 LDDLDKERNEIEELHQTQNELKQQNNLLQKENFVKTETIKNLEDELSQTKSHATNLIKTV 1759

Query: 200  XXXXXXXXXXXXE-DTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANK 258
                        + D K +  K QE  I        EK   L  I SK    +   E N+
Sbjct: 1760 SEKTEIYNSTKQDNDEKDKTIKSQEEIIDKLKNEIKEKTSTLNQINSK---FNDKVEENE 1816

Query: 259  LLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEI 318
             L+         + +L + L+                 K + +   EEK+ +++    ++
Sbjct: 1817 TLKKQISSAKQNNEELERRLDSMFSKVKLFEQQIQDNTK-NYQKIDEEKSNLQKTLRNQV 1875

Query: 319  ANMTEL-TKKIELLEHLNCQIRQTNKE-LE---NKLATMGTESKAVSSPSKKGSPLISRK 373
              + E  TKK EL    N    +TN E L+   N L T   E K  +    +     + K
Sbjct: 1876 VLLDESETKKHELEIKFNTM--KTNFENLQKQFNDLQTKHDELKKENEDQIENLSKENEK 1933

Query: 374  SGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEK-D 432
              RN+   +    +QL SE      D +  K E+  ++   Q+L +++ DK  V +EK +
Sbjct: 1934 FDRNSKDLINKI-TQLESENRQLGGDLQTTKLELEDIKRSKQNL-QEIYDK--VSNEKSE 1989

Query: 433  TXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLK--QELN 490
            T           KD L    QLE     E          T    +I+ +  Q+K  +E  
Sbjct: 1990 TEKSVRELKKQNKDLLG---QLEDITEKE----------TSANGKISSINSQMKTLKEEK 2036

Query: 491  DEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKV 550
            D+++  N K L+E  ++ +E+  +  +EI   N  +    +  K ++++++K+++N   V
Sbjct: 2037 DKLESSNFK-LLEDYRTLKEKSIKEINEIKIQNDKLTNENTTLKNEIERIEKSLENQKSV 2095

Query: 551  SDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDS-GRMIESDVYKKMIEMENLA 609
            +  N  I  LT   + L + ++E+ ++      H+    + G M  +D   K  E+ NL 
Sbjct: 2096 NSQN--ISALTTRNNDLERTISEMRQQ------HMKSISTIGEMTTNDEISKR-EIRNLK 2146

Query: 610  ETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQID 669
            E        +++    +  E  + +Q   E  +K    SQ +++   ++ K   L  QI+
Sbjct: 2147 ENNKNLQEKIDNL---IKNENELKRQISKEKSEKDQQKSQYENEDHENKRKISELSNQIN 2203

Query: 670  ALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSA 729
             LS   K+L   IE LK  K +     KD+  + E  +++L+    +N  L    EK SA
Sbjct: 2204 QLSQENKDLVSQIEELKSSKNKS----KDINKNLEKEIDRLRIENSQNEKLRISAEKYSA 2259

Query: 730  EKISELLAKIN-HEEQSK--IQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIA 786
            E  ++L +  N HE + K  I   F  + ++  + + I N+E E+  YK+    L +   
Sbjct: 2260 ELETKLESIENKHETEKKDIIDRHFAAEQELDSQRIKISNLEQEIEHYKAVEDELRKRQL 2319

Query: 787  VMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVL-------MDHDRVVEK 839
             +   +  ++ K  ++   ++++ K  S+       +  R +V+       +  ++ +  
Sbjct: 2320 TVSPTKSKIDDKNSKI---IEDQTKQISDLHNTISRMAERFSVVESELKSSLSREKTLRN 2376

Query: 840  QLLEIEHENKEL--QKKNQILLEENQ------NLQISLSDMQQHYNA---LVEKANRTDL 888
             +LEI+ E+++L  +K+N++L + N+       L + +S++ Q  N    L E+ N    
Sbjct: 2377 DILEIKSESRKLLSEKQNELLSKTNELSKKDNELMVKVSEISQKQNEIEILKEQLNNMSK 2436

Query: 889  AESESTKYQT-QLRDLESNLKRITHEHQTLIVQ--KKKEIEDLEIEFNTQIESAIRDKKV 945
               ++ +  T Q+ D  + + ++  +   L  +  + + I+DLE +  T   S    +  
Sbjct: 2437 TNDKTIEDLTKQILDKNTTIDQLKSKLIDLSTKSDQSQTIQDLENKLQTLSISTKEKEGT 2496

Query: 946  LNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTE 1005
            +NE  ++N     QL  Q+ E ++NI +    V  LN    E+I +   K      +  +
Sbjct: 2497 INELRQQN----EQLHLQILEKESNIRSEKAKVNHLN----EVISEIQIKNNNNVKNNNQ 2548

Query: 1006 QYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQ 1065
            +YIN+I +L+  L       I  + + N  + SY  +    E +L +  T  +  EE++ 
Sbjct: 2549 EYINQIEQLSRELDSTKRSFITTSNEKNELEKSYHLL----EIRLERSETTNKKYEEQVL 2604

Query: 1066 RVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMII-SSTIEPMSD 1123
            R++ ++ D  + N+E Q+ +   + +++ LK   ++ +  + +T  ++   +T E  +D
Sbjct: 2605 RMTSEIDDLHKSNDEKQLSIERLNRELRSLKSQHISIKTELEETRHLLSDKATTESEND 2663



 Score =  132 bits (319), Expect = 8e-29
 Identities = 286/1512 (18%), Positives = 623/1512 (41%), Gaps = 151/1512 (9%)

Query: 147  LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXX 206
            L+   K+  N +  L  K+K  +  +  LQ   N+  Q  +   K               
Sbjct: 519  LNTKDKDNQNNIKKLLKKLKENDLKLKGLQNDNNKIKQQNQDLLKKIESQEEEKQKLQEL 578

Query: 207  XXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRL-LKDIESKDVRISSL--EEANKLLEAA 263
                 E+ K Q+ K+++     E E  + K ++ L + +  D +++    E+AN++L+  
Sbjct: 579  KDNEIENMKDQIKKLKQILAKNENEKSELKNQISLLENDKNDDKLNDAIKEQANEILQLK 638

Query: 264  ------RFEISLEHSKLAQELE-QXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSL 316
                  + +   E S+L +  E Q              L   +   S        E   +
Sbjct: 639  EQLDDNKIKFENEKSELTKNYEDQLKYLRKQVQNLCKDLVPDAKHSSTNPNDFNNEFNLI 698

Query: 317  EIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISR--KS 374
            +     +LT    L  HLN    + N+     L     E     +   +   ++ R  ++
Sbjct: 699  KDLLNDKLTVIQNLTNHLNGLQNKVNEVATEHLNEANNEPIYALTQISRLILMLKRMNET 758

Query: 375  GRNTASKMKSPWSQLSSET-LNQDTDKKI-NKNEIAK-LEMVIQSLNKDLVDKEYVISEK 431
              +  +K+K   + L  +   N  + +K+ ++N+  K LE ++  LN  L      IS+ 
Sbjct: 759  VNSENNKLKDQVNYLQKDNDKNGVSIRKLQDENDRMKYLENLVNDLNNKLNSAYQAISDY 818

Query: 432  DTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELND 491
            +               +   LQ+  +Q  +           +++ E+  + + L+  ++ 
Sbjct: 819  EIASKNNDALAKKVSEIKLSLQVAAKQIQKYEKA------AQELGEVKNLNDSLRDSISK 872

Query: 492  EIKDVNVKDLIEKLKSAEEQITQLND--EIDAANKNMIKVKSN-----HKLKLKQMQKTI 544
              KDV +K+L  +LK  + +  + +   +    ++N +K   N     HK +++ ++  I
Sbjct: 873  --KDVKIKELTVELKDLQRKSVEFDSFRQKSENDQNTLKDLQNENQFLHK-EIENLKSDI 929

Query: 545  DNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIE 604
             N  K  D+ +  +    E+   SQ   E    K  L     D D+     +D+  K+I 
Sbjct: 930  KNKDKTIDTFQSQILEQTEVFARSQTAIENAMNKSKL-----DDDT----INDMKAKLIS 980

Query: 605  MENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQ----LQSDQVCSEIK 660
              N  E  LK    LE     + ++ H LQ+K  EV +K+  +      + S  V   I 
Sbjct: 981  CRNALEDSLKREDSLEKDIQKVKEKYHKLQEKVTEVTNKIVPVETSVIIINSGSVSQNIS 1040

Query: 661  SVHLEEQIDALSASK-KELALVIENLKLDKEQLYGTIKDLENDKEDIM----NKLQNYIQ 715
             +    +I   +  K K L   +     + E+L   + D+ +  + +     NKL   + 
Sbjct: 1041 DLDSLYKIFTQNDEKIKNLTEKVTQTTENYEKLRKVLTDILSRFDTLSPMDDNKLIEVVM 1100

Query: 716  ENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYK 775
             + ++  K  +    K+ E++   N+ + S ++            DL +   +++  K K
Sbjct: 1101 NDFNVLTKEIEFVRSKLIEIVK--NNTDLSNLKHMNSKKLLNIIIDL-LNQSKADNEKMK 1157

Query: 776  SRICRLEESIAVM--EDRRYSLERKADQL-GSYLQEKQKAYSEYTIQEDELVNRLAVLMD 832
              I  L++++  +  ++  ++ E K   L  S LQ + KA S+   Q + ++ +      
Sbjct: 1158 RDISDLQDTMTTLTTQNSEFAREIKDKDLENSSLQYQIKAISDE--QNESVLAQNEQNKK 1215

Query: 833  HDRVVEK---QLLEIEHENKELQKKNQILLEENQNLQISL-SDMQQHYNALVEKANRTDL 888
             D ++ K   +++++E+  K+L +K    L+E  N   +L S + +  N L +     D 
Sbjct: 1216 RDLLIAKKQNKIVKLENRMKDLLEKTTKSLQEMDNKNKTLNSKVAELTNELSKSKEEIDK 1275

Query: 889  AESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIE-DLEIEFN-TQIESAIRDKK-- 944
              +E +    +   LE+   +I  E +T+I+Q+K E++ + E   N TQ++  +  K+  
Sbjct: 1276 LNNEKSSILEEKSILETEKSKIEQE-KTVILQEKTELQLNFEQTTNQTQLQKDLSQKEFE 1334

Query: 945  ----VLNEKYEKNIEY---VTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQ 997
                ++ EK    +E    + Q + +L   +N+++  N+ + +L +  +E + K  ++Q+
Sbjct: 1335 RLQSIIEEKNISLLEQENTIKQSKNELTNVRNDLQKANLTINDLEE-EMENMRKKNEQQE 1393

Query: 998  TQSPDYTEQYINEINKLNALLKQKDEE-----IIALNQKINNAQVSYMSMVSDYESKLAQ 1052
            T   D  ++ ++++NK    LK ++EE        +++  N+ +   +++  +YE+K+ Q
Sbjct: 1394 TILQD-AQKMVDQLNKQILALKMQNEENETKFKSTIDETENSNKNKELTIRKEYEAKIIQ 1452

Query: 1053 FTTKLENMEEEMQRVSKQLLDSKQHN--EELQILVREQDDQIKELKETKLTFEMNIPKTE 1110
              T  E  + ++++    L +  ++N  E+   ++R Q +Q K   +     + +  +TE
Sbjct: 1453 IQTDNEENKSKLEKKYSDLKNDFENNLKEKETAIMRIQREQKKLTNKMAKALKESDSRTE 1512

Query: 1111 GMIISSTIEPMSDDANNVDXXXXXXXXXXXXLK---VQEEEEFIQERSVLQEQSAKLNTE 1167
               + + +E    +  N+             L+      + ++  E++    +  ++   
Sbjct: 1513 S--VYNELEKSHTEIENLKQKLTESETKVKSLENSLSMTQSQYNDEQTETSNKHKQMKKT 1570

Query: 1168 LQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSA 1227
            + E    I  LET   +L  ++  + ++I +L + LEQ++ +N+     + +L   I  A
Sbjct: 1571 ILELNQTISNLETEKIQLKSNNESSNDRIKRLSTALEQISKKNNESKEDIIKLNKEIKDA 1630

Query: 1228 VDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIV 1287
                        K+ + +     +  + E+  QL   + +YEQ     Q +   ++N   
Sbjct: 1631 ------------KEIINKLNEQIEDKDDEIN-QLKRLQDRYEQ-----QKNQLSQSN--- 1669

Query: 1288 TMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXX 1347
              E +  L +++ +K+  L  ++     V  ++++   +++ E+                
Sbjct: 1670 --EMILKLHDEISEKDRELSEMK----SVKRRLQVALDDLDKER--------NEIEELHQ 1715

Query: 1348 XXXDLRTEN---QSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVN----DAEA 1400
               +L+ +N   Q    ++ ++I N+ +E +Q K  +              N    D + 
Sbjct: 1716 TQNELKQQNNLLQKENFVKTETIKNLEDELSQTKSHATNLIKTVSEKTEIYNSTKQDNDE 1775

Query: 1401 KVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELA 1460
            K   +  Q E+ D ++  +  E T TL Q N +F          +K  E+ T +K+   A
Sbjct: 1776 KDKTIKSQEEIID-KLKNEIKEKTSTLNQINSKFN---------DKVEENETLKKQISSA 1825

Query: 1461 ILRLKMHENANHYETMQKESEIERVKLIEELNVKITESV-SLNKQVAELNKALEEEVAKT 1519
                   +N    E  + +S   +VKL E+     T++   ++++ + L K L  +V   
Sbjct: 1826 ------KQNNEELE-RRLDSMFSKVKLFEQQIQDNTKNYQKIDEEKSNLQKTLRNQVVLL 1878

Query: 1520 NEMQTALENQEIEIVTLNDEITNLQ---NMVRASSSKIQKHVSFASDTKQGRDEQLDNTM 1576
            +E +T     EI+  T+     NLQ   N ++    +++K      +     +E+ D   
Sbjct: 1879 DESETKKHELEIKFNTMKTNFENLQKQFNDLQTKHDELKKENEDQIENLSKENEKFDRN- 1937

Query: 1577 NKELLDAVPRAE 1588
            +K+L++ + + E
Sbjct: 1938 SKDLINKITQLE 1949



 Score =  131 bits (317), Expect = 1e-28
 Identities = 289/1376 (21%), Positives = 572/1376 (41%), Gaps = 169/1376 (12%)

Query: 338  IRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSET--LN 395
            I Q   + +    T  T      SP  +    + ++       K++    QL+S+T  L 
Sbjct: 326  INQMENDQQQSRKTDSTTIHVTQSPVVQQRMKVLQERNLQLEEKLRQTNDQLNSQTAPLT 385

Query: 396  Q-DTDKKINKNEIAKLEMVIQSLNKD-LVDK--EYVISEKDTXXXXXXXXXXGKDTLIAQ 451
            Q   +   N   I +L+  ++S N D   +K  + +++E+                 I +
Sbjct: 386  QLQQNNSQNNTTIVELDSDLESSNSDDEAEKLSKLLMTERSEAEQRLADERDQLKKQIEE 445

Query: 452  LQ-----LEHQQHMEGPSLIHVGTNTEDVN----EIAKVQEQLKQELNDEIKDV-----N 497
            +Q     +++  + +   L    +N +D N    EIAK + Q+K E++ +I+++     N
Sbjct: 446  MQNKIDKMQNDINDKDQQLTQFYSNYDDRNMLKDEIAKKENQIK-EISKQIEEMKKLKEN 504

Query: 498  VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEI 557
             K  I  LKS  E++   + +     K ++K    + LKLK +Q   DN +K+   N+++
Sbjct: 505  DKSDISTLKSLNEELNTKDKDNQNNIKKLLKKLKENDLKLKGLQN--DN-NKIKQQNQDL 561

Query: 558  VRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAE-TRLK-A 615
            ++          K+   EEEK  LQ  L D +   M +     K I  +N  E + LK  
Sbjct: 562  LK----------KIESQEEEKQKLQ-ELKDNEIENMKDQIKKLKQILAKNENEKSELKNQ 610

Query: 616  ISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQI-DALSAS 674
            ISLLE+ K D      I +Q  + ++ K     QL  +++  E +   L +   D L   
Sbjct: 611  ISLLENDKNDDKLNDAIKEQANEILQLK----EQLDDNKIKFENEKSELTKNYEDQLKYL 666

Query: 675  KKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISE 734
            +K++  + ++L  D +       D  N+   I + L + +    +LT+ L  +   K++E
Sbjct: 667  RKQVQNLCKDLVPDAKHSSTNPNDFNNEFNLIKDLLNDKLTVIQNLTNHLNGLQ-NKVNE 725

Query: 735  LLAK-INHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEE-------SIA 786
            +  + +N      I     I   I       E + SE +K K ++  L++       SI 
Sbjct: 726  VATEHLNEANNEPIYALTQISRLILMLKRMNETVNSENNKLKDQVNYLQKDNDKNGVSIR 785

Query: 787  VME---DRRYSLERKADQLGSYLQEKQKAYSEYTI---QEDELVNRLAVLMDHDRVVEKQ 840
             ++   DR   LE   + L + L    +A S+Y I     D L  +++ +    +V  KQ
Sbjct: 786  KLQDENDRMKYLENLVNDLNNKLNSAYQAISDYEIASKNNDALAKKVSEIKLSLQVAAKQ 845

Query: 841  LLEIE---HENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQ 897
            + + E    E  E++  N  L +      + + ++      L  K+   D    +S   Q
Sbjct: 846  IQKYEKAAQELGEVKNLNDSLRDSISKKDVKIKELTVELKDLQRKSVEFDSFRQKSENDQ 905

Query: 898  TQLRDLES----------NLKR-ITHEHQTLIVQKKKEIEDLEI--EFNTQIESAIRDKK 944
              L+DL++          NLK  I ++ +T+   + + +E  E+     T IE+A+   K
Sbjct: 906  NTLKDLQNENQFLHKEIENLKSDIKNKDKTIDTFQSQILEQTEVFARSQTAIENAMNKSK 965

Query: 945  V----LNEKYEKNIEYVTQLEAQLQ---EYKNNIENLNMNVEELNKMNLELIDKHVQKQQ 997
            +    +N+   K I     LE  L+     + +I+ +     +L +   E+ +K V  + 
Sbjct: 966  LDDDTINDMKAKLISCRNALEDSLKREDSLEKDIQKVKEKYHKLQEKVTEVTNKIVPVET 1025

Query: 998  TQ---SPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFT 1054
            +    +     Q I++++ L  +  Q DE+I  L +K+     +Y  +       L++F 
Sbjct: 1026 SVIIINSGSVSQNISDLDSLYKIFTQNDEKIKNLTEKVTQTTENYEKLRKVLTDILSRFD 1085

Query: 1055 T-------KL--------ENMEEEMQRVSKQLLDSKQHNEELQILVREQD--------DQ 1091
            T       KL          + +E++ V  +L++  ++N +L  L             D 
Sbjct: 1086 TLSPMDDNKLIEVVMNDFNVLTKEIEFVRSKLIEIVKNNTDLSNLKHMNSKKLLNIIIDL 1145

Query: 1092 IKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFI 1151
            + + K      + +I   +  + + T +  S+ A  +             +K   +E   
Sbjct: 1146 LNQSKADNEKMKRDISDLQDTMTTLTTQ-NSEFAREIKDKDLENSSLQYQIKAISDE--- 1201

Query: 1152 QERSVL--QEQSAKLNTELQECYTKIIQLETLNTELTGHDVVN-QEQINQ---LKSKLEQ 1205
            Q  SVL   EQ+ K +  + +   KI++LE    +L      + QE  N+   L SK+ +
Sbjct: 1202 QNESVLAQNEQNKKRDLLIAKKQNKIVKLENRMKDLLEKTTKSLQEMDNKNKTLNSKVAE 1261

Query: 1206 LNTENDNLLSTVAELRSSISSAVDQRGFEIAELWK---------QHLAQREADFQKTEHE 1256
            L  E       + +L +  SS ++++     E  K         Q   + + +F++T ++
Sbjct: 1262 LTNELSKSKEEIDKLNNEKSSILEEKSILETEKSKIEQEKTVILQEKTELQLNFEQTTNQ 1321

Query: 1257 LRVQLSAFESKYEQLLDSVQS---STQEETNKI-VTMEQVTSLQNKLQ-------DKEEH 1305
             ++Q    + ++E+L   ++    S  E+ N I  +  ++T+++N LQ       D EE 
Sbjct: 1322 TQLQKDLSQKEFERLQSIIEEKNISLLEQENTIKQSKNELTNVRNDLQKANLTINDLEEE 1381

Query: 1306 LRNLQ-------------EKYADVIN-QIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXD 1351
            + N++             +K  D +N QI  L+ + E+ +  F                 
Sbjct: 1382 MENMRKKNEQQETILQDAQKMVDQLNKQILALKMQNEENETKFKSTIDETENSNKNKELT 1441

Query: 1352 LRTENQS-YKQMQ---EQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTH 1407
            +R E ++   Q+Q   E++   + ++ + LK               R+   + K   LT+
Sbjct: 1442 IRKEYEAKIIQIQTDNEENKSKLEKKYSDLKNDFENNLKEKETAIMRIQREQKK---LTN 1498

Query: 1408 QLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMH 1467
            ++     E   +T      L + + E EN++Q+L E E +++ L        +    +  
Sbjct: 1499 KMAKALKESDSRTESVYNELEKSHTEIENLKQKLTESETKVKSLENSLSMTQSQYNDEQT 1558

Query: 1468 ENANHYETMQKE-SEI-ERVKLIEELNVKI-TESVSLNKQVAELNKALEEEVAKTNEMQT 1524
            E +N ++ M+K   E+ + +  +E   +++ + + S N ++  L+ ALE+   K NE + 
Sbjct: 1559 ETSNKHKQMKKTILELNQTISNLETEKIQLKSNNESSNDRIKRLSTALEQISKKNNESKE 1618

Query: 1525 ALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTK--QGRDEQLDNTMNK 1578
                   +I+ LN EI + + ++   + +I+      +  K  Q R EQ  N +++
Sbjct: 1619 -------DIIKLNKEIKDAKEIINKLNEQIEDKDDEINQLKRLQDRYEQQKNQLSQ 1667



 Score =  125 bits (302), Expect = 9e-27
 Identities = 278/1498 (18%), Positives = 613/1498 (40%), Gaps = 135/1498 (9%)

Query: 160  VLQVKMKIMETTILDLQEKINE-KDQI---------IEAKNKATTXXXXXXXXXXXXXXX 209
            V+Q +MK+++   L L+EK+ +  DQ+         ++  N                   
Sbjct: 351  VVQQRMKVLQERNLQLEEKLRQTNDQLNSQTAPLTQLQQNNSQNNTTIVELDSDLESSNS 410

Query: 210  XXEDTKQQMTKMQENFIAMEAEWKDEKQRLLK--------------DIESKDVRI----S 251
              E  K     M E   A E    DE+ +L K              DI  KD ++    S
Sbjct: 411  DDEAEKLSKLLMTERSEA-EQRLADERDQLKKQIEEMQNKIDKMQNDINDKDQQLTQFYS 469

Query: 252  SLEEANKLL-EAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEI 310
            + ++ N L  E A+ E  ++  ++++++E+              L   + E + ++K   
Sbjct: 470  NYDDRNMLKDEIAKKENQIK--EISKQIEEMKKLKENDKSDISTLKSLNEELNTKDKDNQ 527

Query: 311  EEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLI 370
                 L +  + E   K++ L++ N +I+Q N++L  K+ +   E + +     K + + 
Sbjct: 528  NNIKKL-LKKLKENDLKLKGLQNDNNKIKQQNQDLLKKIESQEEEKQKLQ--ELKDNEIE 584

Query: 371  SRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISE 430
            + K       ++ +      SE  NQ +  + +KN+    + + +  N+ L  KE +   
Sbjct: 585  NMKDQIKKLKQILAKNENEKSELKNQISLLENDKNDDKLNDAIKEQANEILQLKEQLDDN 644

Query: 431  KDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEG--PSLIHVGTNTEDVNEIAKVQEQLKQE 488
            K              +  +  L+ + Q   +   P   H  TN  D N    +   +K  
Sbjct: 645  KIKFENEKSELTKNYEDQLKYLRKQVQNLCKDLVPDAKHSSTNPNDFNNEFNL---IKDL 701

Query: 489  LNDEIKDVNVKDLIEKLKSAEEQITQL-NDEIDAANKNMIKVK---SNHKLKLKQMQKTI 544
            LND++    +++L   L   + ++ ++  + ++ AN   I      S   L LK+M +T+
Sbjct: 702  LNDKL--TVIQNLTNHLNGLQNKVNEVATEHLNEANNEPIYALTQISRLILMLKRMNETV 759

Query: 545  DNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIE 604
            ++ +         ++   + + +S +  + E ++     +LV+ D    + S  Y+ + +
Sbjct: 760  NSENNKLKDQVNYLQKDNDKNGVSIRKLQDENDRMKYLENLVN-DLNNKLNS-AYQAISD 817

Query: 605  MENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEI--KSV 662
             E +A     A++   S+    +Q      QKY++   +L ++  L +D +   I  K V
Sbjct: 818  YE-IASKNNDALAKKVSEIKLSLQVAAKQIQKYEKAAQELGEVKNL-NDSLRDSISKKDV 875

Query: 663  HLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQE--NMDL 720
             ++E    L   +++ ++  ++ +   E    T+KDL+N+ + +  +++N   +  N D 
Sbjct: 876  KIKELTVELKDLQRK-SVEFDSFRQKSENDQNTLKDLQNENQFLHKEIENLKSDIKNKDK 934

Query: 721  T-DKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRIC 779
            T D  +    E+ +E+ A+     ++ +      D  I +    + +  + L     R  
Sbjct: 935  TIDTFQSQILEQ-TEVFARSQTAIENAMNKSKLDDDTINDMKAKLISCRNALEDSLKRED 993

Query: 780  RLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEK 839
             LE+ I  ++++ + L+ K  ++ + +   +   S   I    +   ++   D D +  K
Sbjct: 994  SLEKDIQKVKEKYHKLQEKVTEVTNKIVPVET--SVIIINSGSVSQNIS---DLDSLY-K 1047

Query: 840  QLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNAL--VEKANRTDLAESESTKYQ 897
               + + + K L +K     E  + L+  L+D+   ++ L  ++     ++  ++     
Sbjct: 1048 IFTQNDEKIKNLTEKVTQTTENYEKLRKVLTDILSRFDTLSPMDDNKLIEVVMNDFNVLT 1107

Query: 898  TQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNI--- 954
             ++  + S L  I   +  L   K    + L    N  I+  +   K  NEK +++I   
Sbjct: 1108 KEIEFVRSKLIEIVKNNTDLSNLKHMNSKKL---LNIIID-LLNQSKADNEKMKRDISDL 1163

Query: 955  -EYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEIN- 1012
             + +T L  Q  E+   I++     ++L   +L+   K +  +Q +S     Q  NE N 
Sbjct: 1164 QDTMTTLTTQNSEFAREIKD-----KDLENSSLQYQIKAISDEQNES--VLAQ--NEQNK 1214

Query: 1013 KLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLL 1072
            K + L+ +K  +I+ L  ++ +        + + ++K     +K+  +  E+ + SK+ +
Sbjct: 1215 KRDLLIAKKQNKIVKLENRMKDLLEKTTKSLQEMDNKNKTLNSKVAELTNELSK-SKEEI 1273

Query: 1073 DSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXX 1132
            D K +NE+  IL   ++  I E +++K+  E  +   E   +    E  ++         
Sbjct: 1274 D-KLNNEKSSIL---EEKSILETEKSKIEQEKTVILQEKTELQLNFEQTTNQTQLQKDLS 1329

Query: 1133 XXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVN 1192
                     +  ++    +++ + +++   +L     +     + +  L  E+      N
Sbjct: 1330 QKEFERLQSIIEEKNISLLEQENTIKQSKNELTNVRNDLQKANLTINDLEEEMENMRKKN 1389

Query: 1193 QEQ---INQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREAD 1249
            ++Q   +   +  ++QLN +   L     E  +   S +D+              + EA 
Sbjct: 1390 EQQETILQDAQKMVDQLNKQILALKMQNEENETKFKSTIDETENSNKNKELTIRKEYEAK 1449

Query: 1250 FQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDK-EEHLRN 1308
              + + +     S  E KY  L +  +++ +E+   I+ +++    Q KL +K  + L+ 
Sbjct: 1450 IIQIQTDNEENKSKLEKKYSDLKNDFENNLKEKETAIMRIQRE---QKKLTNKMAKALKE 1506

Query: 1309 LQEKYADVINQIEILRSEIEDEKVAFXXXXX------XXXXXXXXXXXDLRTE-NQSYKQ 1361
               +   V N++E   +EIE+ K                         D +TE +  +KQ
Sbjct: 1507 SDSRTESVYNELEKSHTEIENLKQKLTESETKVKSLENSLSMTQSQYNDEQTETSNKHKQ 1566

Query: 1362 MQE------QSILNINEENAQLKKSSXXX-------XXXXXXXXXRVNDAEAKVLELTHQ 1408
            M++      Q+I N+  E  QLK ++                   + N+++  +++L   
Sbjct: 1567 MKKTILELNQTISNLETEKIQLKSNNESSNDRIKRLSTALEQISKKNNESKEDIIKLNK- 1625

Query: 1409 LELKDS-EIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMH 1467
             E+KD+ EI  K +E    +  ++DE   +++    YE++   L+   E     + LK+H
Sbjct: 1626 -EIKDAKEIINKLNE---QIEDKDDEINQLKRLQDRYEQQKNQLSQSNE-----MILKLH 1676

Query: 1468 ENANHYETMQKESEIERVKLIE-ELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTAL 1526
            +     E  +K+ E+  +K ++  L V + +      ++ EL++   E   + N +Q   
Sbjct: 1677 D-----EISEKDRELSEMKSVKRRLQVALDDLDKERNEIEELHQTQNELKQQNNLLQKEN 1731

Query: 1527 ENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTM--NKELLD 1582
              +   I  L DE++  ++        + +     + TKQ  DE+ D T+   +E++D
Sbjct: 1732 FVKTETIKNLEDELSQTKSHATNLIKTVSEKTEIYNSTKQDNDEK-DKTIKSQEEIID 1788



 Score = 84.2 bits (199), Expect = 3e-14
 Identities = 198/1121 (17%), Positives = 430/1121 (38%), Gaps = 117/1121 (10%)

Query: 516  NDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELE 575
            N E+ + N+ +++  +  KL + Q      +  K S++        EE   L  ++AEL+
Sbjct: 207  NQELASQNEKLVRENTQLKLNISQNSMNASSDQKFSENLNLNSANDEEKEKLRSQLAELQ 266

Query: 576  EEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQ 635
              K N Q    + +S  +    + +   +++         I++L  +   L  E   L+Q
Sbjct: 267  S-KINKQ----NANSQEIFAQQISQAKEQLQKFQTD----IAILIDKNNKLKDENTKLKQ 317

Query: 636  KYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGT 695
               E + ++  I+Q+++DQ  S            +    ++   L   NL+L+ E+L  T
Sbjct: 318  ---ETQQQMYFINQMENDQQQSRKTDSTTIHVTQSPVVQQRMKVLQERNLQLE-EKLRQT 373

Query: 696  IKDLENDKEDIMNKLQNYIQEN---MDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFG 752
               L +    +    QN  Q N   ++L   LE  +++  +E L+K+   E+S+ + +  
Sbjct: 374  NDQLNSQTAPLTQLQQNNSQNNTTIVELDSDLESSNSDDEAEKLSKLLMTERSEAEQRLA 433

Query: 753  IDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKA 812
                  ERD     ++ ++ + +++I +++  I            K  QL  +       
Sbjct: 434  -----DERD----QLKKQIEEMQNKIDKMQNDI----------NDKDQQLTQFYSN---- 470

Query: 813  YSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDM 872
            Y +  + +DE+  +     +  + + KQ+ E++   +  +     L   N+ L     D 
Sbjct: 471  YDDRNMLKDEIAKK----ENQIKEISKQIEEMKKLKENDKSDISTLKSLNEELNTKDKDN 526

Query: 873  QQHYNALVEKANRTDL----AESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDL 928
            Q +   L++K    DL     ++++ K + Q +DL   ++    E Q L   K  EIE++
Sbjct: 527  QNNIKKLLKKLKENDLKLKGLQNDNNKIKQQNQDLLKKIESQEEEKQKLQELKDNEIENM 586

Query: 929  -----------------EIEFNTQIESAIRDKK--VLNEKYEKNIEYVTQLEAQLQEYKN 969
                             + E   QI     DK    LN+  ++    + QL+ QL + K 
Sbjct: 587  KDQIKKLKQILAKNENEKSELKNQISLLENDKNDDKLNDAIKEQANEILQLKEQLDDNKI 646

Query: 970  NIENLNMNVEELNKMNLELIDKHVQK-------QQTQSPDYTEQYINEINKLNALLKQK- 1021
              EN    + +  +  L+ + K VQ            S      + NE N +  LL  K 
Sbjct: 647  KFENEKSELTKNYEDQLKYLRKQVQNLCKDLVPDAKHSSTNPNDFNNEFNLIKDLLNDKL 706

Query: 1022 ------DEEIIALNQKINNAQVSYMSMVSDYE----SKLAQFTTKLENMEEEMQRVSKQL 1071
                     +  L  K+N     +++  ++      +++++    L+ M E +   + +L
Sbjct: 707  TVIQNLTNHLNGLQNKVNEVATEHLNEANNEPIYALTQISRLILMLKRMNETVNSENNKL 766

Query: 1072 LDS----KQHNEELQILVR---EQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDD 1124
             D     ++ N++  + +R   +++D++K L+         +      I    I   ++D
Sbjct: 767  KDQVNYLQKDNDKNGVSIRKLQDENDRMKYLENLVNDLNNKLNSAYQAISDYEIASKNND 826

Query: 1125 ANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKI----IQLET 1180
            A                 ++Q+ E+  QE   ++  +  L   + +   KI    ++L+ 
Sbjct: 827  ALAKKVSEIKLSLQVAAKQIQKYEKAAQELGEVKNLNDSLRDSISKKDVKIKELTVELKD 886

Query: 1181 LNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWK 1240
            L  +    D   Q+  N  ++ L+ L  EN  L   +  L+S I +    +   I     
Sbjct: 887  LQRKSVEFDSFRQKSEND-QNTLKDLQNENQFLHKEIENLKSDIKN----KDKTIDTFQS 941

Query: 1241 QHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQ 1300
            Q L Q E  F +++  +   ++  +   + + D              ++++  SL+  +Q
Sbjct: 942  QILEQTEV-FARSQTAIENAMNKSKLDDDTINDMKAKLISCRNALEDSLKREDSLEKDIQ 1000

Query: 1301 DKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYK 1360
              +E    LQEK  +V N+I      +E   +                   + T+N    
Sbjct: 1001 KVKEKYHKLQEKVTEVTNKI----VPVETSVIIINSGSVSQNISDLDSLYKIFTQNDEKI 1056

Query: 1361 QMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKT 1420
            +   + +    E   +L+K                ++   +V+     +  K+ E  +  
Sbjct: 1057 KNLTEKVTQTTENYEKLRKVLTDILSRFDTLSPMDDNKLIEVVMNDFNVLTKEIEFVRSK 1116

Query: 1421 HEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKES 1480
                I + + N +  N++       K++ ++  +  ++      KM  + +  +      
Sbjct: 1117 ---LIEIVKNNTDLSNLKHM---NSKKLLNIIIDLLNQSKADNEKMKRDISDLQDTMTTL 1170

Query: 1481 EIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEI 1540
              +  +   E+  K  E+ SL  Q+  ++    E V   NE     + +++ I    ++I
Sbjct: 1171 TTQNSEFAREIKDKDLENSSLQYQIKAISDEQNESVLAQNEQN---KKRDLLIAKKQNKI 1227

Query: 1541 TNLQNMVR---ASSSKIQKHVSFASDTKQGRDEQLDNTMNK 1578
              L+N ++     ++K  + +   + T   +  +L N ++K
Sbjct: 1228 VKLENRMKDLLEKTTKSLQEMDNKNKTLNSKVAELTNELSK 1268



 Score = 48.0 bits (109), Expect = 0.002
 Identities = 89/435 (20%), Positives = 171/435 (39%), Gaps = 33/435 (7%)

Query: 1165 NTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSI 1224
            NT+       +  L +L+ E T     N+  +  +   L QLNT N + +    E R   
Sbjct: 135  NTDSIISLVPLTNLRSLDLEGTQLSF-NESVLLFITFTLPQLNTLNRDTIQL--EYRRKA 191

Query: 1225 SSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLS------AFESKYEQLLDSVQSS 1278
            +    +          Q LA +     +   +L++ +S      + + K+ + L+ + S+
Sbjct: 192  AERYSRSQLNDLYRENQELASQNEKLVRENTQLKLNISQNSMNASSDQKFSENLN-LNSA 250

Query: 1279 TQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXX 1338
              EE  K+    Q+  LQ+K+  +     N QE +A  I+Q +    + + +        
Sbjct: 251  NDEEKEKL--RSQLAELQSKINKQNA---NSQEIFAQQISQAKEQLQKFQTD-------- 297

Query: 1339 XXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDA 1398
                         L+ EN   KQ  +Q +  IN+     ++S              V   
Sbjct: 298  ---IAILIDKNNKLKDENTKLKQETQQQMYFINQMENDQQQSRKTDSTTIHVTQSPVVQQ 354

Query: 1399 EAKVL-ELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKES 1457
              KVL E   QLE K  +   + +  T  LTQ           +VE +  +E    + E+
Sbjct: 355  RMKVLQERNLQLEEKLRQTNDQLNSQTAPLTQLQQNNSQNNTTIVELDSDLESSNSDDEA 414

Query: 1458 ELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVS-LNKQVAELNKALEEEV 1516
            E  + +L M E +   + +  E + +  K IEE+  KI +  + +N +  +L +      
Sbjct: 415  E-KLSKLLMTERSEAEQRLADERD-QLKKQIEEMQNKIDKMQNDINDKDQQLTQ-FYSNY 471

Query: 1517 AKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTM 1576
               N ++  +  +E +I  ++ +I  ++ +     S I    S  ++    +D+   N +
Sbjct: 472  DDRNMLKDEIAKKENQIKEISKQIEEMKKLKENDKSDISTLKSL-NEELNTKDKDNQNNI 530

Query: 1577 NKELLDAVPRAELDL 1591
             K+LL  +   +L L
Sbjct: 531  -KKLLKKLKENDLKL 544


>UniRef50_A0C3N5 Cluster: Chromosome undetermined scaffold_147, whole
            genome shotgun sequence; n=3; Paramecium tetraurelia|Rep:
            Chromosome undetermined scaffold_147, whole genome
            shotgun sequence - Paramecium tetraurelia
          Length = 3822

 Score =  158 bits (384), Expect = 1e-36
 Identities = 288/1485 (19%), Positives = 623/1485 (41%), Gaps = 128/1485 (8%)

Query: 156  NALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTK 215
            N  + L++ ++  E+ I   Q+ I E+   +    +                    ++  
Sbjct: 283  NQSNQLEIILQQKESEISSFQQLIQEQKDKLTLIQQQYQDLEFLHLYEAQIIEKNNQELL 342

Query: 216  QQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLA 275
             Q+  +Q+    + +E KD + + ++  + ++  IS L    +LLE    ++ L ++KL 
Sbjct: 343  NQIDNLQQQISNLTSELKDSEVKHIQVKQMQETTISKLNHDVRLLEQKNEDLILHNNKLI 402

Query: 276  QELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLN 335
             E++Q                 +      E + +IE+          E  K++ ++E LN
Sbjct: 403  NEIKQNELNQQKESTIICQKNSEFEIQLLESQHQIEDL-------KQEKQKQVHVVEMLN 455

Query: 336  CQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLN 395
             Q+ Q   + ++KL    T+ +       K    I+     +++   + P ++  S+ LN
Sbjct: 456  RQL-QVQVQAQSKLEEDITKYQNFLISHDKQLEAITSNESSDSSDSSEEPVTE-KSQQLN 513

Query: 396  QDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQL--- 452
             D        +I  +++ ++   K +   +  +  K T            +  + +L   
Sbjct: 514  FDALCNKLTEKIRLIQLRLEIYEKQIKQYKQELHSKTTEIQKLFSENSESNLKVQRLSQI 573

Query: 453  --QLEHQQHMEGPSLIHVGTNTEDVN-EIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAE 509
              +LE+Q   +  SL       E++  +  K+Q Q K     EI++  + +L  ++K  +
Sbjct: 574  QPKLENQLENQEESLKQKDQTIENLTLQNTKLQIQFK-----EIEESKL-ELENQIKLLQ 627

Query: 510  EQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFS-KVSDSNKEIVRLTEELHHLS 568
            E   Q +  +D  N+ + + KS   LK++++ +  +NF  ++ +S  ++ +L  E   L+
Sbjct: 628  ED--QQSQSLDFQNQILAQAKS-QDLKIEELTRINNNFEIQLIESENKLKQLQIENESLN 684

Query: 569  QKVA----ELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKF 624
             K+A    EL   +  LQL LV  +  +   + + ++ I+  NL+      +S+ + Q F
Sbjct: 685  LKIASSDIELSNLQNQLQLELVIKNDLQSNLNSIKEEQIQNFNLSNGETTEVSVFD-QVF 743

Query: 625  DLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIEN 684
              +    +L    +E+ +K+ +  Q++ D +   +  + + +    L   +K    +   
Sbjct: 744  PNINYQMVLFT--EELTEKIKNNLQIKMDSLDKNLLRI-INKYQKLLEKVQKNYHNIQNL 800

Query: 685  LKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQ 744
             +L ++ L       ++ KE + N++    +E       + ++  ++   LL   N E+Q
Sbjct: 801  YELSQQTLIQQESAYQDQKEKLSNQINTLQEEINSKNSHIHQLEDQQKKLLLDLSNIEQQ 860

Query: 745  SK------IQTQFGID----AKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYS 794
            ++       Q Q  +D     KI E +  + N +SEL +  ++  +LE+ +   + + +S
Sbjct: 861  NQDKQIIINQQQLKLDEIHKTKIVELEKIVTNQQSELEQILTKSNQLEQQVQDQKSQIHS 920

Query: 795  LERKADQLGSYL----------QEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEI 844
             + + ++L   L          Q  Q  + +   Q  EL++    L   +  ++++L ++
Sbjct: 921  KQNRINELKQELNHLKNDQTGVQIDQLKFQQQQNQILELISNNTNLTQQNLDIQRRLKQV 980

Query: 845  EHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKA-----------NRTDLAESES 893
            E  N+ LQ K   L ++  + +  ++ +QQ   + V+++            + D    E+
Sbjct: 981  EDSNQALQDKINQLTKQGASQKEIINQLQQQNQSEVKQSLALMQQMDPLQKQIDFLTREN 1040

Query: 894  TKYQTQLRDLESNLKR--ITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYE 951
             K Q    D E    +  I        VQ   +I+ LE E   QI+  +R +K + EK +
Sbjct: 1041 RKLQQSNTDFEKAYGKLPIYGSPSPKKVQNNDQIKKLEDELQ-QIQ--LRFQKEMGEK-D 1096

Query: 952  KNIEYVT-QLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINE 1010
            K I +++ Q E QLQ+ K      ++N +E+NK+    I    + +Q Q      + + E
Sbjct: 1097 KEINHISIQYEFQLQQQK------DLNQDEINKLEQNCITFSNELKQQQI--LNNKLLEE 1148

Query: 1011 INKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQ 1070
              K+     Q  E++  L Q++N    +   M +  ES+L +F    +   +E Q++ K 
Sbjct: 1149 NGKVEREKLQLIEKVEKLTQQLNECSQN-QQMFAQQESELKRFIVLHQQALDENQKLQKL 1207

Query: 1071 LLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDX 1130
             ++ ++ N+ L+   ++Q     +L++    F+  + + +G              N V+ 
Sbjct: 1208 FINLEEENKNLK---QQQSLLSTQLEQQYNEFQSEVKQQKG--------------NYVEQ 1250

Query: 1131 XXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDV 1190
                            E++  +    LQ    + N    E Y K+I  +    + +  D+
Sbjct: 1251 EHLHLEQIKTL-----EQKLCEINGELQNNQMQFN-NTNESYEKVIADKNEQLQNSKKDI 1304

Query: 1191 VNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQ-RGFEIAELWKQHLAQREAD 1249
              Q+   Q+ + L+Q+N +  NL   + E    I + +++ +  E+    KQ   Q++ D
Sbjct: 1305 --QDLQKQINNSLDQIN-QFKNL---IEEKEQQIQNCINESKQIEVDYKNKQQSLQQQID 1358

Query: 1250 FQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQ-NKLQDKEEHLRN 1308
             Q+ E     + +  + + +     VQ S Q+  N I   EQ+ S + N+ +D    L+N
Sbjct: 1359 DQQ-EQLQNSKNNVLDLQQQIANQDVQISQQK--NVIQQKEQLISNKINQSKDLNLELQN 1415

Query: 1309 LQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDL-RTENQSYKQMQEQSI 1367
              EK   +I+ + +     +D  +                   +   E Q   ++ E   
Sbjct: 1416 KLEKLQQLIDDLNLKLKNSQDNTLDLQQQINLQEDQINKQKNIIEEKEKQLQAKINESKQ 1475

Query: 1368 LNINEENAQ--LKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTI 1425
            + IN  N Q  L+K               V D + ++     Q+  + + I QK    +I
Sbjct: 1476 IEINNINKQQSLQKQIDDQQEQLQNSKNIVLDLQKQIANQEIQINQQKNVIQQKEQLISI 1535

Query: 1426 TLTQRNDEFENVRQQLVEYEKRIEDLTYEKESEL---AILRLKMH---ENANHYETMQKE 1479
             + Q ND    ++ +L   ++ I+DL  + ++ L     L+ +++   +  N Y+ + +E
Sbjct: 1536 KINQSNDLNLELQNKLENLQQLIDDLNLQLKNSLDNNLDLQQQLNLQQDQINKYKNIIEE 1595

Query: 1480 SEIE-RVKLIEELNVK---ITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVT 1535
             E E + K+ E   ++   I +  SL KQ+ +  + L+       ++Q  + NQ+++I  
Sbjct: 1596 KEKEIQAKINESKQIEVDYINKQYSLQKQIDDQQEQLQNSKNNILDLQKQVANQDVQINQ 1655

Query: 1536 LNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKEL 1580
             N+ I   + +++   ++    ++     K    +QL + +N +L
Sbjct: 1656 QNNVIQQKEELMQIKLNQ-SNDLNLQLQNKLENLQQLIDDLNSQL 1699



 Score =  150 bits (364), Expect = 3e-34
 Identities = 287/1471 (19%), Positives = 652/1471 (44%), Gaps = 120/1471 (8%)

Query: 147  LSNTIKEKDNALSVLQVKMKIMETTILDLQEKIN-EKDQIIEAKNKATTXXXXXXXXXXX 205
            L N ++     +  L +++K      LDLQ+++N ++DQI + KN               
Sbjct: 1547 LQNKLENLQQLIDDLNLQLKNSLDNNLDLQQQLNLQQDQINKYKNIIEEKEKEIQAKINE 1606

Query: 206  XXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLL---KDIESKDVRISSLEEANKLLEA 262
                  +   +Q + +Q+     + + ++ K  +L   K + ++DV+I+      +  E 
Sbjct: 1607 SKQIEVDYINKQYS-LQKQIDDQQEQLQNSKNNILDLQKQVANQDVQINQQNNVIQQKEE 1665

Query: 263  ARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMT 322
               +I L  S    +L                     ++ S      +++   L+   M 
Sbjct: 1666 L-MQIKLNQSN---DLNLQLQNKLENLQQLIDDLNSQLQTSKNNNQNLQQLKKLQEDQMN 1721

Query: 323  ELTKKIELLEH-LNCQIRQTNK-ELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTAS 380
            +    IE  E+ L  QI +  K E++NK      +   +S  + +    ++R S  +   
Sbjct: 1722 QYKNLIEEKENQLQIQINEQQKIEIDNKNTIENLQKLQISINNLQDLQKLTR-SQEDQIK 1780

Query: 381  KMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDK-EYVISEKDTXXXXXX 439
            + K+   Q  +E     ++ K +KN         QSL K + D  E + + K+T      
Sbjct: 1781 QYKNLIDQKETEI---QSNIKESKNLEIDYNNKQQSLQKQIADSTEQLQNAKNTIQDLQK 1837

Query: 440  XXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTN-TEDVN-EIAKVQEQLKQELND---EIK 494
                 +  +  Q ++ HQ+      LI +  N + ++N E+   QE L++ ++D   ++K
Sbjct: 1838 QIANQEIQINQQEKVIHQKE----ELISLKINQSNNLNLELQNKQEHLQEIIDDLSLQLK 1893

Query: 495  DV--NVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSD 552
            +   N   L +++K  E+QI +  + I+   K + + K N     KQM+  I+N +K   
Sbjct: 1894 NSQDNTLALQQQIKLKEDQIYKYQNIIEEKEKQL-QAKINES---KQME--INNINKQQS 1947

Query: 553  SNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETR 612
              ++I    E+L +    + +L+++  N  + +    +  +I+       I++    +  
Sbjct: 1948 LQQQIDDQQEQLQNSKCNILDLQKQVANQDVQISQQKN--VIQQKEQLISIKINQSNDLN 2005

Query: 613  LKAISLLESQKFDLVQELHI-LQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDAL 671
            L+  + LE+ +  L+ +L++ L+   D   D    I +LQ DQ+  + K++ +EE+   L
Sbjct: 2006 LELQNKLENLQ-QLIVDLNLQLKNSQDNTLDLQQQI-KLQEDQIY-KYKNI-IEEKEKQL 2061

Query: 672  SASKKELALVIENLKLDKEQ-LYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAE 730
             A   E +  +E   ++K+Q L   I D +   ++  N +QN  Q+ +   D+++K   +
Sbjct: 2062 QAKINE-SKQMEINNINKQQSLQQQIDDQQEQLQNSKNNIQNLQQQLISQEDQIKKYHNQ 2120

Query: 731  -KISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVME 789
             + +E+  ++ ++  + I     ++ K+ + +  I NI+  ++  +++I   +E     +
Sbjct: 2121 IQENEIAYQVQNQNSNSINQT--LNQKLIDSENQILNIQKLINDEQNKI---QEQQKQFK 2175

Query: 790  DRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLL--EIEHE 847
            + +  +E   +QL    ++  +   E  +Q   ++N +  L++ +++ ++QL+  +++ +
Sbjct: 2176 EEKEKVELVLEQLTLENKKSTQLVKEQEVQIS-MLNDIK-LVNENQLDQEQLINNQLKKD 2233

Query: 848  NKELQKK-NQILL-EENQNLQISL--SDMQQHYNAL-VEKANRTDLAESESTKYQTQLRD 902
            N E ++K NQ+L+ EE+Q  QIS   S ++   + L   K  + + A+ +  +Y+  +++
Sbjct: 2234 NLEKEQKINQLLIIEEDQKNQISKLNSQIKNEQDILNTLKIQQDEDAKYQIKEYEQIIKN 2293

Query: 903  LESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEA 962
            L+  +K + + ++  I +++ E+++ +I+   + +  I  ++ L ++ EK +E  ++  +
Sbjct: 2294 LQVEVKEVANINKK-IFEQQIELDNNKIKL-IESQDKIHKQESLIKQLEKAVESNSE-SS 2350

Query: 963  QLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDY--TEQYINEINKLNALLKQ 1020
              Q+ ++  E LN   +++   ++ ++++  Q +  +  DY   ++ + E+N      + 
Sbjct: 2351 SFQKEQHQAE-LNFKQKQIEDKDIVILEQDTQIRNLKE-DYHNLQKQLQEMNHKIQTDQA 2408

Query: 1021 KDEEIIALNQ----KINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQ 1076
             +EE   L Q    K+ +      +++   + +  + T + +  +E  + + +Q+     
Sbjct: 2409 YNEESCRLFQTKLDKLESQNKDKENIIQQLQVQSQEITKQYDKSQELNEELKQQINGQSD 2468

Query: 1077 HNEELQILVREQDDQIKELKETKLTFEM-------NIPKTEGMI------ISSTIEPMSD 1123
               + Q  ++  +D+I +L  T +T+E        N  K E  I      +    + +SD
Sbjct: 2469 QLNQKQQQIQSLEDKITQLSNTNITYEQKNTEFIQNFNKQEQQINELNNMVKVLTQEISD 2528

Query: 1124 DA----NNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLE 1179
                  N +             L+ + +E  I+    +++Q      + Q+    + Q  
Sbjct: 2529 KEDKYKNEIVQQKKEYLSDKLSLENRIKESMIEWNQKVEDQRKHYENQHQDMENNLNQER 2588

Query: 1180 TLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELW 1239
             L+ +   ++     +I  L+  LE+ + +N +LLS++ ELRS   +  +Q   E  +  
Sbjct: 2589 ILSKQFEENNKELSLRIQNLEMILEKHSQDNADLLSSIEELRSENHN--NQSELEKIKKD 2646

Query: 1240 KQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKL 1299
            K+ L   E  +Q+ E++    + + +S  E L +  Q +      KIV  EQ +++Q ++
Sbjct: 2647 KEEL---EVKYQQMEYQKNESVDSNKSLQEMLFELKQIN-----EKIV--EQNSAIQREM 2696

Query: 1300 QDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFX----XXXXXXXXXXXXXXXDLRTE 1355
             + +   ++L+++Y+ +IN+   L  ++ ++K A                      +R E
Sbjct: 2697 GEIQSMNQSLEKRYSLLINEKSSLLEQVREQKSALADQCQQYIQLDSQFNQMQQNFIRIE 2756

Query: 1356 NQS-----YKQMQEQSILNINEENAQ-LKKSSXXXXXXXXXXXXRVNDAEAKVL------ 1403
            +QS       Q  EQS+    + N Q ++K              ++ D + +V       
Sbjct: 2757 SQSNSLKQINQQLEQSLQQQQQVNTQIIQKQEQQYQQQLDQLTLQLQDGQNQVRLLQQKN 2816

Query: 1404 -ELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAIL 1462
             E   ++++  ++  Q  +     + Q   E E   Q+L++   ++E L  + ++E  IL
Sbjct: 2817 GEQRQEIQMIRNDQKQWENNKVNEMVQMKQESERQIQKLMDQVSQVEGLNKQYQNE--IL 2874

Query: 1463 RLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNE- 1521
             L    N    +  +K+      +++E+L  K+  S    +++   N+AL EE A   E 
Sbjct: 2875 EL---NNIIKKQFEEKDKSSVNNQVVEQLQTKLKLSEEQIERLLMTNRALMEENANLQEQ 2931

Query: 1522 MQTALENQEIEIVTLNDEITNLQNMVRASSS 1552
            ++  L +      + N    N +N V   S+
Sbjct: 2932 IKDDLNSSFCSNASQNCATKNQENEVSLPSN 2962



 Score =  147 bits (355), Expect = 3e-33
 Identities = 270/1529 (17%), Positives = 641/1529 (41%), Gaps = 89/1529 (5%)

Query: 93   SLANTLKQKEILMEKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIK 152
            +L + LK  E+   ++KQ +E +       VR                + ++    N + 
Sbjct: 354  NLTSELKDSEVKHIQVKQMQETTISKLNHDVRLLEQKNEDLILHNNKLINEIKQ--NELN 411

Query: 153  EKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXE 212
            ++  +  + Q K    E  +L+ Q +I +  Q  + +                      E
Sbjct: 412  QQKESTIICQ-KNSEFEIQLLESQHQIEDLKQEKQKQVHVVEMLNRQLQVQVQAQSKLEE 470

Query: 213  DTKQQMTKMQENFIAMEA----EWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEIS 268
            D  +    +  +   +EA    E  D      + +  K  +++     NKL E  R  I 
Sbjct: 471  DITKYQNFLISHDKQLEAITSNESSDSSDSSEEPVTEKSQQLNFDALCNKLTEKIRL-IQ 529

Query: 269  LEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEK--TEIEEKGSLEIANMTE-LT 325
            L      ++++Q              L  ++ E + + +  ++I+ K   ++ N  E L 
Sbjct: 530  LRLEIYEKQIKQYKQELHSKTTEIQKLFSENSESNLKVQRLSQIQPKLENQLENQEESLK 589

Query: 326  KKIELLEHL---NCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKM 382
            +K + +E+L   N +++   KE+E     +  + K +    +  S L  +      A   
Sbjct: 590  QKDQTIENLTLQNTKLQIQFKEIEESKLELENQIKLLQEDQQSQS-LDFQNQILAQAKSQ 648

Query: 383  KSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXX 442
                 +L+    N +     ++N++ +L++  +SLN  +   +  +S             
Sbjct: 649  DLKIEELTRINNNFEIQLIESENKLKQLQIENESLNLKIASSDIELSNLQNQLQLELVI- 707

Query: 443  XGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLI 502
              K+ L + L    ++ ++  +L + G  TE       V +Q+   +N ++  +  ++L 
Sbjct: 708  --KNDLQSNLNSIKEEQIQNFNLSN-GETTE-----VSVFDQVFPNINYQMV-LFTEELT 758

Query: 503  EKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTE 562
            EK+K+       L  ++D+ +KN++++ + ++  L+++QK   N   + + +++ + + +
Sbjct: 759  EKIKN------NLQIKMDSLDKNLLRIINKYQKLLEKVQKNYHNIQNLYELSQQTL-IQQ 811

Query: 563  ELHHLSQKVAELEEEKGNLQLHLVDYDSG-RMIESDVYKKMIEMENLAETRLKAISLLES 621
            E  +  QK  +L  +   LQ  +   +S    +E    K ++++ N+ +       ++  
Sbjct: 812  ESAYQDQK-EKLSNQINTLQEEINSKNSHIHQLEDQQKKLLLDLSNIEQQNQDKQIIINQ 870

Query: 622  QKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALV 681
            Q+  L  E+H  + K  E+E K+    Q + +Q+ +  KS  LE+Q+    +        
Sbjct: 871  QQLKL-DEIH--KTKIVELE-KIVTNQQSELEQILT--KSNQLEQQVQDQKSQIHSKQNR 924

Query: 682  IENLKLDKEQLYGTIKDLENDK---EDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAK 738
            I  LK +   L      ++ D+   +   N++   I  N +LT   + +  ++  + +  
Sbjct: 925  INELKQELNHLKNDQTGVQIDQLKFQQQQNQILELISNNTNLTQ--QNLDIQRRLKQVED 982

Query: 739  INHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERK 798
             N   Q KI       A   ++++  +  +   S+ K  +  +++   + +   + L R+
Sbjct: 983  SNQALQDKINQLTKQGAS--QKEIINQLQQQNQSEVKQSLALMQQMDPLQKQIDF-LTRE 1039

Query: 799  ADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHE-NKELQKKNQI 857
              +L     + +KAY +  I       ++    D  + +E +L +I+    KE+ +K++ 
Sbjct: 1040 NRKLQQSNTDFEKAYGKLPIYGSPSPKKVQN-NDQIKKLEDELQQIQLRFQKEMGEKDKE 1098

Query: 858  LLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRD--LESNLKRITHEHQ 915
            +   +   +  L   +      + K  +  +  S   K Q  L +  LE N K +  E  
Sbjct: 1099 INHISIQYEFQLQQQKDLNQDEINKLEQNCITFSNELKQQQILNNKLLEENGK-VEREKL 1157

Query: 916  TLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLN 975
             LI + +K  + L      Q   A ++ ++  +++    +       +LQ+   N+E  N
Sbjct: 1158 QLIEKVEKLTQQLNECSQNQQMFAQQESEL--KRFIVLHQQALDENQKLQKLFINLEEEN 1215

Query: 976  MNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNA 1035
             N+++   +    +++   + Q++       Y+ + +     +K  ++++  +N ++ N 
Sbjct: 1216 KNLKQQQSLLSTQLEQQYNEFQSEVKQQKGNYVEQEHLHLEQIKTLEQKLCEINGELQNN 1275

Query: 1036 QVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIK-- 1093
            Q+ + +    YE  +A    +L+N ++++Q + KQ+ +S     + + L+ E++ QI+  
Sbjct: 1276 QMQFNNTNESYEKVIADKNEQLQNSKKDIQDLQKQINNSLDQINQFKNLIEEKEQQIQNC 1335

Query: 1094 --ELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFI 1151
              E K+ ++ ++ N  ++    I    E + +  NNV             +++ +++  I
Sbjct: 1336 INESKQIEVDYK-NKQQSLQQQIDDQQEQLQNSKNNV--LDLQQQIANQDVQISQQKNVI 1392

Query: 1152 QERSVL----QEQSAKLNTELQECYTKIIQL-ETLNTELTGHDVVNQEQINQLKSKLEQL 1206
            Q++  L      QS  LN ELQ    K+ QL + LN +L        +   Q+  + +Q+
Sbjct: 1393 QQKEQLISNKINQSKDLNLELQNKLEKLQQLIDDLNLKLKNSQDNTLDLQQQINLQEDQI 1452

Query: 1207 NTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFES 1266
            N + + +     +L++ I+   + +  EI  + KQ   Q++ D Q  + +L+   +    
Sbjct: 1453 NKQKNIIEEKEKQLQAKIN---ESKQIEINNINKQQSLQKQIDDQ--QEQLQNSKNIVLD 1507

Query: 1267 KYEQLLDSVQSSTQEETNKIVTMEQVTSLQ-NKLQDKEEHLRNLQEKYADVINQIEI-LR 1324
              +Q+ +  +    ++ N I   EQ+ S++ N+  D    L+N  E    +I+ + + L+
Sbjct: 1508 LQKQIANQ-EIQINQQKNVIQQKEQLISIKINQSNDLNLELQNKLENLQQLIDDLNLQLK 1566

Query: 1325 SEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQ--LKKSSX 1382
            + +++                         E +   ++ E   + ++  N Q  L+K   
Sbjct: 1567 NSLDNNLDLQQQLNLQQDQINKYKNIIEEKEKEIQAKINESKQIEVDYINKQYSLQKQID 1626

Query: 1383 XXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLV 1442
                        + D + +V     Q+  +++ I QK     I L Q ND    ++ +L 
Sbjct: 1627 DQQEQLQNSKNNILDLQKQVANQDVQINQQNNVIQQKEELMQIKLNQSNDLNLQLQNKLE 1686

Query: 1443 EYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLN 1502
              ++ I+DL  + ++         ++N    + +Q++   +   LIEE   ++   ++  
Sbjct: 1687 NLQQLIDDLNSQLQTS-----KNNNQNLQQLKKLQEDQMNQYKNLIEEKENQLQIQINEQ 1741

Query: 1503 KQVAELNKALEEEVAKTNEMQTALEN-QEIEIVTLN--DEITNLQNMVRASSSKIQKHVS 1559
            +++   NK   E + K   +Q ++ N Q+++ +T +  D+I   +N++    ++IQ ++ 
Sbjct: 1742 QKIEIDNKNTIENLQK---LQISINNLQDLQKLTRSQEDQIKQYKNLIDQKETEIQSNIK 1798

Query: 1560 FASDTKQGRDEQLDNTMNKELLDAVPRAE 1588
             + + +   + +   ++ K++ D+  + +
Sbjct: 1799 ESKNLEIDYNNK-QQSLQKQIADSTEQLQ 1826



 Score =  143 bits (346), Expect = 4e-32
 Identities = 304/1570 (19%), Positives = 681/1570 (43%), Gaps = 180/1570 (11%)

Query: 147  LSNTIKEKDNALSVLQVKMKIMETTILDLQEKIN-EKDQIIEAKNKATTXXXXXXXXXXX 205
            L N +++    +  L +K+K  +   LDLQ++IN ++DQI + KN               
Sbjct: 1413 LQNKLEKLQQLIDDLNLKLKNSQDNTLDLQQQINLQEDQINKQKNIIEEKEKQLQAKINE 1472

Query: 206  XXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLL---KDIESKDVRISS----LEEANK 258
                   +  +Q + +Q+     + + ++ K  +L   K I +++++I+     +++  +
Sbjct: 1473 SKQIEINNINKQQS-LQKQIDDQQEQLQNSKNIVLDLQKQIANQEIQINQQKNVIQQKEQ 1531

Query: 259  LLEAA-------RFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQ---SIEPSCEEKT 308
            L+            E+  +   L Q ++               L +Q     +   + K 
Sbjct: 1532 LISIKINQSNDLNLELQNKLENLQQLIDDLNLQLKNSLDNNLDLQQQLNLQQDQINKYKN 1591

Query: 309  EIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSP 368
             IEEK     A + E +K+IE+ +++N Q     K+++++   +      +    K+ + 
Sbjct: 1592 IIEEKEKEIQAKINE-SKQIEV-DYINKQY-SLQKQIDDQQEQLQNSKNNILDLQKQVAN 1648

Query: 369  LISRKSGRNTASKMKSPWSQLSSETLNQDTDKKIN-KNEIAKLEMVIQSLNKDLVDKEYV 427
               + + +N   + K    Q+    LNQ  D  +  +N++  L+ +I  LN  L   +  
Sbjct: 1649 QDVQINQQNNVIQQKEELMQIK---LNQSNDLNLQLQNKLENLQQLIDDLNSQLQTSKNN 1705

Query: 428  ISEKDTXXXXXXXXXXGKDTLIA------QLQLEHQQHME--------GPSLIHVGTNT- 472
                                LI       Q+Q+  QQ +E            + +  N  
Sbjct: 1706 NQNLQQLKKLQEDQMNQYKNLIEEKENQLQIQINEQQKIEIDNKNTIENLQKLQISINNL 1765

Query: 473  EDVNEIAKVQE-QLKQ----------ELNDEIKDV-NVK-DLIEKLKSAEEQITQLNDEI 519
            +D+ ++ + QE Q+KQ          E+   IK+  N++ D   K +S ++QI    +++
Sbjct: 1766 QDLQKLTRSQEDQIKQYKNLIDQKETEIQSNIKESKNLEIDYNNKQQSLQKQIADSTEQL 1825

Query: 520  DAAN---KNMIKVKSNHKLKLKQMQKTIDNFS-----KVSDSNKEIVRLTEELHHLSQKV 571
              A    +++ K  +N ++++ Q +K I         K++ SN   + L  +  HL + +
Sbjct: 1826 QNAKNTIQDLQKQIANQEIQINQQEKVIHQKEELISLKINQSNNLNLELQNKQEHLQEII 1885

Query: 572  AELEEEKGNLQLHLVDYDSG-RMIESDVYKKMIEMENLAETRLKAISLLESQKFDL--VQ 628
             +L  +  N Q + +      ++ E  +YK    +E   E +L+A  + ES++ ++  + 
Sbjct: 1886 DDLSLQLKNSQDNTLALQQQIKLKEDQIYKYQNIIEE-KEKQLQA-KINESKQMEINNIN 1943

Query: 629  ELHILQQKYDEVEDKL----ADISQLQSD------QVCSEIKSVHLEEQIDALSASKK-E 677
            +   LQQ+ D+ +++L     +I  LQ        Q+  +   +  +EQ+ ++  ++  +
Sbjct: 1944 KQQSLQQQIDDQQEQLQNSKCNILDLQKQVANQDVQISQQKNVIQQKEQLISIKINQSND 2003

Query: 678  LALVIENLKLDKEQLYGTIK-DLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELL 736
            L L ++N   + +QL   +   L+N +++ ++ LQ  I+   D   K + +  EK  +L 
Sbjct: 2004 LNLELQNKLENLQQLIVDLNLQLKNSQDNTLD-LQQQIKLQEDQIYKYKNIIEEKEKQLQ 2062

Query: 737  AKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMED--RRYS 794
            AKIN  +Q +I     I+ K Q     I++ + +L   K+ I  L++ +   ED  ++Y 
Sbjct: 2063 AKINESKQMEINN---IN-KQQSLQQQIDDQQEQLQNSKNNIQNLQQQLISQEDQIKKYH 2118

Query: 795  LERKADQLGSYLQEKQKAYSEYTIQ------EDELVNRLAVLMDHDRVVEKQLLEIEHEN 848
             + + +++   +Q +       T+       E++++N   ++ D    +++Q  + + E 
Sbjct: 2119 NQIQENEIAYQVQNQNSNSINQTLNQKLIDSENQILNIQKLINDEQNKIQEQQKQFKEEK 2178

Query: 849  KELQKK-NQILLEENQNLQISLSDMQQHYNAL--VEKANRTDLAESESTKYQTQLRDLES 905
            ++++    Q+ LE  ++ Q+ + + +   + L  ++  N   L + +    Q +  +LE 
Sbjct: 2179 EKVELVLEQLTLENKKSTQL-VKEQEVQISMLNDIKLVNENQLDQEQLINNQLKKDNLEK 2237

Query: 906  NLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQ 965
              K     +Q LI+++ ++ +  ++  N+QI++   ++ +LN      I+     + Q++
Sbjct: 2238 EQKI----NQLLIIEEDQKNQISKL--NSQIKN---EQDILNTL---KIQQDEDAKYQIK 2285

Query: 966  EYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDE-- 1023
            EY+  I+NL + V+E+  +N ++ ++ ++    +      Q  ++I+K  +L+KQ ++  
Sbjct: 2286 EYEQIIKNLQVEVKEVANINKKIFEQQIELDNNKIKLIESQ--DKIHKQESLIKQLEKAV 2343

Query: 1024 ----EIIALNQKINNAQVSY-MSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHN 1078
                E  +  ++ + A++++    + D +  + +  T++ N++E+   + KQL   ++ N
Sbjct: 2344 ESNSESSSFQKEQHQAELNFKQKQIEDKDIVILEQDTQIRNLKEDYHNLQKQL---QEMN 2400

Query: 1079 EELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXX 1138
             ++Q      ++  + L +TKL    +  K +  II        +     D         
Sbjct: 2401 HKIQTDQAYNEESCR-LFQTKLDKLESQNKDKENIIQQLQVQSQEITKQYD--------- 2450

Query: 1139 XXXLKVQE-EEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQIN 1197
                K QE  EE  Q+ +   +Q  +   ++Q    KI QL   NT +T ++  N E I 
Sbjct: 2451 ----KSQELNEELKQQINGQSDQLNQKQQQIQSLEDKITQLS--NTNIT-YEQKNTEFIQ 2503

Query: 1198 QLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHEL 1257
                + +Q+N  N+     V  L   IS   D+   EI +  K++L+    D    E+ +
Sbjct: 2504 NFNKQEQQINELNN----MVKVLTQEISDKEDKYKNEIVQQKKEYLS----DKLSLENRI 2555

Query: 1258 RVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLR--NLQ---EK 1312
            +  +  +  K E      ++  Q+  N +   E++ S Q +  +KE  LR  NL+   EK
Sbjct: 2556 KESMIEWNQKVEDQRKHYENQHQDMENNL-NQERILSKQFEENNKELSLRIQNLEMILEK 2614

Query: 1313 Y----ADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSY---KQMQEQ 1365
            +    AD+++ IE LRSE  + +                       +N+S    K +QE 
Sbjct: 2615 HSQDNADLLSSIEELRSENHNNQSELEKIKKDKEELEVKYQQMEYQKNESVDSNKSLQEM 2674

Query: 1366 --SILNINE----ENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQK 1419
               +  INE    +N+ +++              R +    +   L  Q+  + S +  +
Sbjct: 2675 LFELKQINEKIVEQNSAIQREMGEIQSMNQSLEKRYSLLINEKSSLLEQVREQKSALADQ 2734

Query: 1420 THEYTITLTQRND------EFENVRQQLVEYEKRIED-LTYEKESELAILRLKMHENANH 1472
              +Y    +Q N         E+    L +  +++E  L  +++    I++ +  +    
Sbjct: 2735 CQQYIQLDSQFNQMQQNFIRIESQSNSLKQINQQLEQSLQQQQQVNTQIIQKQEQQYQQQ 2794

Query: 1473 YE--TMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQE 1530
             +  T+Q +    +V+L+++ N +  + + + +     N   + E  K NEM    +  E
Sbjct: 2795 LDQLTLQLQDGQNQVRLLQQKNGEQRQEIQMIR-----NDQKQWENNKVNEMVQMKQESE 2849

Query: 1531 IEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDE-QLDNTMNKELLDAVPRAEL 1589
             +I  L D+++ ++ + +   ++I +  +      + +D+  ++N + ++L   +  +E 
Sbjct: 2850 RQIQKLMDQVSQVEGLNKQYQNEILELNNIIKKQFEEKDKSSVNNQVVEQLQTKLKLSEE 2909

Query: 1590 DLAMYMLHQR 1599
             +   ++  R
Sbjct: 2910 QIERLLMTNR 2919



 Score =  136 bits (330), Expect = 4e-30
 Identities = 292/1479 (19%), Positives = 635/1479 (42%), Gaps = 183/1479 (12%)

Query: 216  QQMTKMQEN----FIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271
            QQM   QE+    FI +  +  DE Q+L K   + +    +L++   LL     ++  ++
Sbjct: 1177 QQMFAQQESELKRFIVLHQQALDENQKLQKLFINLEEENKNLKQQQSLLST---QLEQQY 1233

Query: 272  SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKI--- 328
            ++   E++Q                K   +  CE   E++    ++  N  E  +K+   
Sbjct: 1234 NEFQSEVKQQKGNYVEQEHLHLEQIKTLEQKLCEINGELQNN-QMQFNNTNESYEKVIAD 1292

Query: 329  --ELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLI--SRKSGRNTASKMKS 384
              E L++    I+   K++ N L  +      +    ++    I  S++   +  +K +S
Sbjct: 1293 KNEQLQNSKKDIQDLQKQINNSLDQINQFKNLIEEKEQQIQNCINESKQIEVDYKNKQQS 1352

Query: 385  PWSQLSS--ETLNQDTDKKIN-KNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXX 441
               Q+    E L    +  ++ + +IA  ++ I      +  KE +IS K          
Sbjct: 1353 LQQQIDDQQEQLQNSKNNVLDLQQQIANQDVQISQQKNVIQQKEQLISNKINQSKDLNLE 1412

Query: 442  XXGK----DTLIAQLQLEHQQHMEGPSLIHVGTNTED------VNEIAKVQEQLKQELND 491
               K      LI  L L+ +   +    +    N ++       N I + ++QL+ ++N 
Sbjct: 1413 LQNKLEKLQQLIDDLNLKLKNSQDNTLDLQQQINLQEDQINKQKNIIEEKEKQLQAKIN- 1471

Query: 492  EIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMI----KVKSNHKLKLKQMQKTIDNF 547
            E K + + + I K +S ++QI    +++  + KN++    K  +N ++++ Q +  I   
Sbjct: 1472 ESKQIEINN-INKQQSLQKQIDDQQEQLQNS-KNIVLDLQKQIANQEIQINQQKNVIQQK 1529

Query: 548  S-----KVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDV---Y 599
                  K++ SN   + L  +L +L Q + +L  +  N   + +D      ++ D    Y
Sbjct: 1530 EQLISIKINQSNDLNLELQNKLENLQQLIDDLNLQLKNSLDNNLDLQQQLNLQQDQINKY 1589

Query: 600  KKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLAD----ISQLQSDQV 655
            K +IE E   E + K I+  +  + D + + + LQ++ D+ +++L +    I  LQ  QV
Sbjct: 1590 KNIIE-EKEKEIQAK-INESKQIEVDYINKQYSLQKQIDDQQEQLQNSKNNILDLQK-QV 1646

Query: 656  CSEIKSVHLEEQIDALSASKKELALVIE-----NLKLDK--EQLYGTIKDLENDKEDIMN 708
             ++   V + +Q + +   ++ + + +      NL+L    E L   I DL +  +   N
Sbjct: 1647 ANQ--DVQINQQNNVIQQKEELMQIKLNQSNDLNLQLQNKLENLQQLIDDLNSQLQTSKN 1704

Query: 709  KLQNYIQENM---DLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIE 765
              QN  Q      D  ++ + +  EK ++L  +IN +++ +I  +  I+  +Q+  + I 
Sbjct: 1705 NNQNLQQLKKLQEDQMNQYKNLIEEKENQLQIQINEQQKIEIDNKNTIE-NLQKLQISIN 1763

Query: 766  NI----------ESELSKYKSRICRLEESIA--VMEDRRYSLE--RKADQLGSYLQE--K 809
            N+          E ++ +YK+ I + E  I   + E +   ++   K   L   + +  +
Sbjct: 1764 NLQDLQKLTRSQEDQIKQYKNLIDQKETEIQSNIKESKNLEIDYNNKQQSLQKQIADSTE 1823

Query: 810  QKAYSEYTIQE--DELVNRLAVLMDHDRVVEKQ----LLEIEHENK---ELQKKNQILLE 860
            Q   ++ TIQ+   ++ N+   +   ++V+ ++     L+I   N    ELQ K + L E
Sbjct: 1824 QLQNAKNTIQDLQKQIANQEIQINQQEKVIHQKEELISLKINQSNNLNLELQNKQEHLQE 1883

Query: 861  ENQNLQISLSDMQ------------------QHYNALVEKANRTDLAESESTKYQTQLRD 902
               +L + L + Q                  ++ N + EK  +     +ES + +    +
Sbjct: 1884 IIDDLSLQLKNSQDNTLALQQQIKLKEDQIYKYQNIIEEKEKQLQAKINESKQMEINNIN 1943

Query: 903  LESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEA 962
             + +L++   + Q  +   K  I DL+ +   Q     + K V+ +K +     + Q   
Sbjct: 1944 KQQSLQQQIDDQQEQLQNSKCNILDLQKQVANQDVQISQQKNVIQQKEQLISIKINQSND 2003

Query: 963  QLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKD 1022
               E +N +ENL   + +L   NL+L  K+ Q          +   ++I K   ++++K+
Sbjct: 2004 LNLELQNKLENLQQLIVDL---NLQL--KNSQDNTLDLQQQIKLQEDQIYKYKNIIEEKE 2058

Query: 1023 EEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQ 1082
            ++   L  KIN ++   ++ ++           K +++++++    +QL +SK + + LQ
Sbjct: 2059 KQ---LQAKINESKQMEINNIN-----------KQQSLQQQIDDQQEQLQNSKNNIQNLQ 2104

Query: 1083 ILVREQDDQIK----ELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXX 1138
              +  Q+DQIK    +++E ++ +++    +    I+ T+     D+ N           
Sbjct: 2105 QQLISQEDQIKKYHNQIQENEIAYQVQNQNSNS--INQTLNQKLIDSEN-QILNIQKLIN 2161

Query: 1139 XXXLKVQEEE-EFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQIN 1197
                K+QE++ +F +E+  ++    +L  E ++    + + E   + L    +VN+ Q++
Sbjct: 2162 DEQNKIQEQQKQFKEEKEKVELVLEQLTLENKKSTQLVKEQEVQISMLNDIKLVNENQLD 2221

Query: 1198 QLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHEL 1257
            Q +    QL  +N   L    ++   +    DQ+  +I++L  Q   + E D   T   L
Sbjct: 2222 QEQLINNQLKKDN---LEKEQKINQLLIIEEDQKN-QISKLNSQ--IKNEQDILNT---L 2272

Query: 1258 RVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVI 1317
            ++Q    ++KY+     ++   Q   N  V +++V ++  K+ +++  L N + K  +  
Sbjct: 2273 KIQQDE-DAKYQ-----IKEYEQIIKNLQVEVKEVANINKKIFEQQIELDNNKIKLIESQ 2326

Query: 1318 NQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQL 1377
            ++I    S I+  + A                 +L   N   KQ++++ I+ I E++ Q+
Sbjct: 2327 DKIHKQESLIKQLEKAVESNSESSSFQKEQHQAEL---NFKQKQIEDKDIV-ILEQDTQI 2382

Query: 1378 KKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQ---RNDEF 1434
            +                 ++ + ++ E+ H+++   +   +    +   L +   +N + 
Sbjct: 2383 RNLKED-----------YHNLQKQLQEMNHKIQTDQAYNEESCRLFQTKLDKLESQNKDK 2431

Query: 1435 ENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEI----ERVKLIEE 1490
            EN+ QQL    + I    Y+K  EL    LK   N    +  QK+ +I    +++  +  
Sbjct: 2432 ENIIQQLQVQSQEITK-QYDKSQELN-EELKQQINGQSDQLNQKQQQIQSLEDKITQLSN 2489

Query: 1491 LNV----KITESV-SLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVT-----LNDEI 1540
             N+    K TE + + NKQ  ++N+        T E+    +  + EIV      L+D++
Sbjct: 2490 TNITYEQKNTEFIQNFNKQEQQINELNNMVKVLTQEISDKEDKYKNEIVQQKKEYLSDKL 2549

Query: 1541 TNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKE 1579
             +L+N ++ S  +  + V       + + + ++N +N+E
Sbjct: 2550 -SLENRIKESMIEWNQKVEDQRKHYENQHQDMENNLNQE 2587



 Score =  126 bits (305), Expect = 4e-27
 Identities = 217/1093 (19%), Positives = 456/1093 (41%), Gaps = 88/1093 (8%)

Query: 144  VTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXX 203
            +  LS  +K   +    LQ ++K+ E  I   Q  I EK++ ++AK   +          
Sbjct: 1885 IDDLSLQLKNSQDNTLALQQQIKLKEDQIYKYQNIIEEKEKQLQAKINESKQMEINNINK 1944

Query: 204  XXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKD---IESKDVRIS-SLEEANKL 259
                    +D ++Q+   + N + ++ +  ++  ++ +    I+ K+  IS  + ++N L
Sbjct: 1945 QQSLQQQIDDQQEQLQNSKCNILDLQKQVANQDVQISQQKNVIQQKEQLISIKINQSNDL 2004

Query: 260  LEAARFEISLEH-SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEI 318
                  +  LE+  +L  +L                  K   +   + K  IEEK     
Sbjct: 2005 --NLELQNKLENLQQLIVDLNLQLKNSQDNTLDLQQQIKLQEDQIYKYKNIIEEKEKQLQ 2062

Query: 319  ANMTELTKKIEL-----LEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRK 373
            A + E +K++E+      + L  QI    ++L+N    +    + + S   +     ++ 
Sbjct: 2063 AKINE-SKQMEINNINKQQSLQQQIDDQQEQLQNSKNNIQNLQQQLISQEDQIKKYHNQI 2121

Query: 374  SGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDT 433
                 A ++++  S   ++TLNQ      ++N+I  ++ +I      + +++    E+  
Sbjct: 2122 QENEIAYQVQNQNSNSINQTLNQKLID--SENQILNIQKLINDEQNKIQEQQKQFKEEKE 2179

Query: 434  XXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEI 493
                       ++    QL  E +  +   + I +  N   +++   +  QLK++  ++ 
Sbjct: 2180 KVELVLEQLTLENKKSTQLVKEQEVQISMLNDIKL-VNENQLDQEQLINNQLKKDNLEKE 2238

Query: 494  KDVNVKDLIEKLKSAEEQITQLNDEI----DAANKNMIKVKSNHKLKLKQMQKTIDNF-- 547
            + +N   +IE  +  + QI++LN +I    D  N   I+   + K ++K+ ++ I N   
Sbjct: 2239 QKINQLLIIE--EDQKNQISKLNSQIKNEQDILNTLKIQQDEDAKYQIKEYEQIIKNLQV 2296

Query: 548  --SKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEM 605
               +V++ NK+I     EL +   K+ E  ++K + Q  L+     + +ES+      + 
Sbjct: 2297 EVKEVANINKKIFEQQIELDNNKIKLIE-SQDKIHKQESLIK-QLEKAVESNSESSSFQK 2354

Query: 606  E-NLAETRLKAISLLESQKFDLVQELHI--LQQKYDEVEDKLADIS-QLQSDQVCSEIKS 661
            E + AE   K   + +     L Q+  I  L++ Y  ++ +L +++ ++Q+DQ  +E   
Sbjct: 2355 EQHQAELNFKQKQIEDKDIVILEQDTQIRNLKEDYHNLQKQLQEMNHKIQTDQAYNEESC 2414

Query: 662  VHLEEQIDALSASKKELALVIENLKL---------DKEQ-LYGTIKDLENDKEDIMNKLQ 711
               + ++D L +  K+   +I+ L++         DK Q L   +K   N + D +N+ Q
Sbjct: 2415 RLFQTKLDKLESQNKDKENIIQQLQVQSQEITKQYDKSQELNEELKQQINGQSDQLNQKQ 2474

Query: 712  NYIQENMDLTDKLEKMS---AEKISELLAKINHEEQS--------KIQTQFGIDAKIQER 760
              IQ   D   +L   +    +K +E +   N +EQ         K+ TQ   D + + +
Sbjct: 2475 QQIQSLEDKITQLSNTNITYEQKNTEFIQNFNKQEQQINELNNMVKVLTQEISDKEDKYK 2534

Query: 761  DLYIENIESELSKYKSRICRLEESI----AVMEDRRYSLERKADQLGSYLQEKQKAYSEY 816
            +  ++  +  LS   S   R++ES+      +ED+R   E +   + + L +++    ++
Sbjct: 2535 NEIVQQKKEYLSDKLSLENRIKESMIEWNQKVEDQRKHYENQHQDMENNLNQERILSKQF 2594

Query: 817  TIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHY 876
                 EL  R+  L   + ++EK       +N +L    + L  EN N Q  L  +++  
Sbjct: 2595 EENNKELSLRIQNL---EMILEKH----SQDNADLLSSIEELRSENHNNQSELEKIKKDK 2647

Query: 877  NALVEKANRTDLAESESTKYQTQLRDLESNLKRITH---EHQTLIVQKKKEIEDLEIEFN 933
              L  K  + +  ++ES      L+++   LK+I     E  + I ++  EI+ +     
Sbjct: 2648 EELEVKYQQMEYQKNESVDSNKSLQEMLFELKQINEKIVEQNSAIQREMGEIQSMNQSLE 2707

Query: 934  TQIESAIRDKKVLNEKYEK-------NIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNL 986
             +    I +K  L E+  +         +   QL++Q  + + N   +      L ++N 
Sbjct: 2708 KRYSLLINEKSSLLEQVREQKSALADQCQQYIQLDSQFNQMQQNFIRIESQSNSLKQINQ 2767

Query: 987  ELIDKHVQKQQTQS---PDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMV 1043
            +L     Q+QQ  +       +QY  ++++L   L+    ++  L QK N  Q   + M+
Sbjct: 2768 QLEQSLQQQQQVNTQIIQKQEQQYQQQLDQLTLQLQDGQNQVRLLQQK-NGEQRQEIQMI 2826

Query: 1044 -SDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKE-TKLT 1101
             +D +        ++  M++E +R  ++L+D     E L    ++  ++I EL    K  
Sbjct: 2827 RNDQKQWENNKVNEMVQMKQESERQIQKLMDQVSQVEGLN---KQYQNEILELNNIIKKQ 2883

Query: 1102 FEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQS 1161
            FE    K +  + +  +E +       +            L   EE   +QE+      S
Sbjct: 2884 FE---EKDKSSVNNQVVEQLQTKLKLSEEQIERLLMTNRAL--MEENANLQEQIKDDLNS 2938

Query: 1162 AKLNTELQECYTK 1174
            +  +   Q C TK
Sbjct: 2939 SFCSNASQNCATK 2951



 Score =  113 bits (271), Expect = 5e-23
 Identities = 207/1086 (19%), Positives = 467/1086 (43%), Gaps = 106/1086 (9%)

Query: 493  IKDVNVKD--LIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKV 550
            +K VN     LI+KL   +E I  LN+EI+A+N+ +  ++S H L L Q    I++    
Sbjct: 10   LKQVNKNQTLLIQKL---QEDIQVLNEEIEASNQQIDTLRSEHHLALSQQLSLIEDLRNE 66

Query: 551  SDS----NKEI-VRLTEELHHLSQKVAELEEEKGNLQ--------------LHLVDYDSG 591
            S +    N E+  + T+ +  L  ++ + + +K N Q              +HL + D  
Sbjct: 67   SQNYQQQNMELQTKFTQSV--LQNQLLQTKYDKKNKQYKDQIIELKQQIKLIHLKNQDYQ 124

Query: 592  RMIESDVYKKMIEMENLAETRLK-AISLLESQKFDLVQELHILQQKYDEVEDKLADISQL 650
            R I     +K ++++ L  ++     S+L  Q   L   L + +  Y+   +++ ++ Q 
Sbjct: 125  REIID--LRKSLDVKKLELSKFNDNSSILNEQNNQLKANLDLQKVDYENKIEQIQNLIQD 182

Query: 651  QSDQVCSEIKSVHL-----EEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKED 705
            + +++   +    L      E I+A +   + L   I  L+   + L   + DL N+   
Sbjct: 183  KDEEITLILNDNKLLNKTNLELIEANANQSQTLQSQINTLEQHNQTLQIQLSDLLNENNL 242

Query: 706  IMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIE 765
            +  + Q   QE   +   ++  SA +  + + ++ +        Q  ++  +Q+++  I 
Sbjct: 243  LKQQFQQQTQEMQVIPSSIQLQSAAESQQEMVQLQNSNLLNQSNQ--LEIILQQKESEIS 300

Query: 766  NIESELSKYKSRICRLEESIAVME----DRRYSLERKADQLGSYLQEKQKAYSEYTIQ-E 820
            + +  + + K ++  +++    +E         +E+   +L + +   Q+  S  T + +
Sbjct: 301  SFQQLIQEQKDKLTLIQQQYQDLEFLHLYEAQIIEKNNQELLNQIDNLQQQISNLTSELK 360

Query: 821  DELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALV 880
            D  V  + V    +  + K    + H+ + L++KN+ L+  N  L   +++++Q  N L 
Sbjct: 361  DSEVKHIQVKQMQETTISK----LNHDVRLLEQKNEDLILHNNKL---INEIKQ--NELN 411

Query: 881  EKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAI 940
            ++   T + +  S +++ QL  LES      H+ + L  +K+K++  +E+  N Q++  +
Sbjct: 412  QQKESTIICQKNS-EFEIQL--LESQ-----HQIEDLKQEKQKQVHVVEM-LNRQLQVQV 462

Query: 941  RDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMN------VEELNKMNLELIDKHVQ 994
            + +  L E   K   ++   + QL+   +N  + + +       E+  ++N + +   + 
Sbjct: 463  QAQSKLEEDITKYQNFLISHDKQLEAITSNESSDSSDSSEEPVTEKSQQLNFDALCNKLT 522

Query: 995  KQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFT 1054
            ++        E Y  +I +    L  K  EI  L  + + + +  +  +S  + KL    
Sbjct: 523  EKIRLIQLRLEIYEKQIKQYKQELHSKTTEIQKLFSENSESNLK-VQRLSQIQPKL---E 578

Query: 1055 TKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMII 1114
             +LEN EE +++  + + +    N +LQI       Q KE++E+KL  E  I   +    
Sbjct: 579  NQLENQEESLKQKDQTIENLTLQNTKLQI-------QFKEIEESKLELENQIKLLQEDQQ 631

Query: 1115 SSTIEPMSD---DANNVDXXXXXXXXXXXXLKVQ--EEEEFIQERSVLQEQSAKLNTELQ 1169
            S +++  +     A + D             ++Q  E E  +++   LQ ++  LN ++ 
Sbjct: 632  SQSLDFQNQILAQAKSQDLKIEELTRINNNFEIQLIESENKLKQ---LQIENESLNLKIA 688

Query: 1170 ECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVD 1229
               +  I+L  L  +L    V+  +  + L S +++   +N NL +      S       
Sbjct: 689  ---SSDIELSNLQNQLQLELVIKNDLQSNLNS-IKEEQIQNFNLSNGETTEVSVFDQVFP 744

Query: 1230 QRGFEIAELWKQHLAQR-EADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVT 1288
               +++  L+ + L ++ + + Q     L   L    +KY++LL+ VQ +     N +  
Sbjct: 745  NINYQMV-LFTEELTEKIKNNLQIKMDSLDKNLLRIINKYQKLLEKVQKNYHNIQN-LYE 802

Query: 1289 MEQVTSLQNK--LQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXX 1346
            + Q T +Q +   QD++E L N      + IN       ++ED++               
Sbjct: 803  LSQQTLIQQESAYQDQKEKLSNQINTLQEEINSKNSHIHQLEDQQKKLLLDLSNIEQQNQ 862

Query: 1347 XXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELT 1406
                 +  +     ++ +  I+ + +     +               +V D ++++    
Sbjct: 863  DKQIIINQQQLKLDEIHKTKIVELEKIVTNQQSELEQILTKSNQLEQQVQDQKSQIHSKQ 922

Query: 1407 HQL-ELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLK 1465
            +++ ELK    + K  +  + + Q   +F+  + Q++E      +LT ++  ++   RLK
Sbjct: 923  NRINELKQELNHLKNDQTGVQIDQL--KFQQQQNQILELISNNTNLT-QQNLDIQ-RRLK 978

Query: 1466 MHENAN-------HYETMQKESEIERVKLIEELN-VKITESVSLNKQVAELNKALEEEVA 1517
              E++N       +  T Q  S+ E +  +++ N  ++ +S++L +Q+  L K ++    
Sbjct: 979  QVEDSNQALQDKINQLTKQGASQKEIINQLQQQNQSEVKQSLALMQQMDPLQKQIDFLTR 1038

Query: 1518 KTNEMQ 1523
            +  ++Q
Sbjct: 1039 ENRKLQ 1044



 Score = 35.9 bits (79), Expect = 9.2
 Identities = 68/356 (19%), Positives = 162/356 (45%), Gaps = 38/356 (10%)

Query: 642  DKLADISQLQSDQVCSEIKSVHLEEQIDA-LSASKKELALVI--ENLKLDKEQLYGTIKD 698
            DKL  I +L  +      K+++L+      +  SK+  +++   +++KL    +    K 
Sbjct: 3236 DKLDKIKKLNPNSSVDG-KTMYLKPSFKTKMKTSKRYFSVIFSPQSMKLKTSSMLTQKKT 3294

Query: 699  LENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLA----KINHEEQSKIQ--TQFG 752
            L + ++ + + +++YI+  +  +    K   +KI +L +    +I  + + KI+  T  G
Sbjct: 3295 LPSPQKPLKDIVKHYIKSKIPKSRTPSKSPPQKIKKLSSPQQRQIRSQSKKKIKYKTTIG 3354

Query: 753  IDAKIQERDLY--IEN--IESELSKYKSRICRLEESIAVMED-RRYSLERKADQLGSYLQ 807
               K+ +++    I+N   + ++SK  S   RL  + +V ED  R  + +  D+L   + 
Sbjct: 3355 SPNKLTKKNKKQKIQNQYYQPQISKVSS--IRLN-TFSVSEDPHRMLMNQIIDEL-QQMN 3410

Query: 808  EKQKAYSEYTIQ--EDELVNRLAVLMDHDRV-VE-KQLLEIEHENKELQKKNQILLEENQ 863
            EKQ    +  ++  + + V+       H+++ ++ K   +  HE+  L   N+I  +   
Sbjct: 3411 EKQIIDLQQFLKNIKQQKVDEALQTSLHEKIDIQLKHQQKAFHESLPLNIINEICQQRES 3470

Query: 864  NLQISLSDMQQHYNALVEKANRTDLA-----------ESESTKYQTQLRDLESNLKRITH 912
             + + +      ++ L+E+   +  +           +S+ST    + +++   ++ +T+
Sbjct: 3471 TINVRVKMQMDAFSTLLEQQKISPRSFNKNGQVLEQWKSQSTDKLHKCQEILQQMQSVTN 3530

Query: 913  EHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYK 968
            + Q   +Q  K I++LE   N+ +E    D   L     +++     ++ Q Q++K
Sbjct: 3531 KIQQKTIQDMKLIQELESN-NSILEQMSADSSYLE---SQDLHLHNPIQNQQQDFK 3582


>UniRef50_A2EPG1 Cluster: Viral A-type inclusion protein, putative;
            n=1; Trichomonas vaginalis G3|Rep: Viral A-type inclusion
            protein, putative - Trichomonas vaginalis G3
          Length = 1297

 Score =  157 bits (382), Expect = 2e-36
 Identities = 247/1164 (21%), Positives = 508/1164 (43%), Gaps = 128/1164 (10%)

Query: 470  TNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKV 529
            T T+  N + +V+  LKQ+L D  KDV  + + E  +   +++ Q+ +++   ++  I++
Sbjct: 16   TITQRDNALEEVKN-LKQQLEDSKKDV--ESITEDFEKTSDELEQVKEKLALKDQTEIEL 72

Query: 530  KSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYD 589
            +     ++ Q+++ I N S  + +NK    L EE+  L  +  E++E    L+ +     
Sbjct: 73   QK----EITQLKEQIQNLSTEATNNKS---LNEEIQRLKSENTEIKEA---LERNKTQNK 122

Query: 590  SGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLV------QELHILQQKYDEVEDK 643
                 E  + +   E + L +      S +ES K +L       +EL     + DE+ +K
Sbjct: 123  ENSENEEVINQLTGENQKLTDENESLKSQIESLKKELSKLNQNQEELLKASGQTDELNNK 182

Query: 644  LADISQLQSDQVCSEIKSVHLEEQ-----IDALSAS----KKELALVIENLKLDKEQLYG 694
            L+++ + ++  +  ++KS+  E       +  L         E+  VI NL+ +K  L  
Sbjct: 183  LSNL-EAENKSLTEKLKSLENENSTLLGFVSTLKTQFNNMNTEVQRVIGNLEAEKTNLE- 240

Query: 695  TIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGID 754
              ++ EN KE+   +L  +  +   L D++ ++  E  +E L KI  E + +IQ +  I 
Sbjct: 241  --EEFENYKENSHKQLDVHYNKITSLEDEISQLKKE--NENLIKIK-EIKEEIQVEL-IH 294

Query: 755  AKIQERDLY--IENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKA 812
             K +   L    E+++ EL   K+ +   E+ I   E++  +LE + D+L + ++E    
Sbjct: 295  MKQENEKLKKESESLQDELDTAKADLEDKEDEIEDKENQISNLEEETDELNAKIEELNST 354

Query: 813  YSEYTIQED--ELVNRLAVLMDHDRV--VEKQLLEI-------EHENKELQKKN---QIL 858
              + +  +   E  N++    ++ R+  +EKQ+ E+       E   +E+QK N   + L
Sbjct: 355  IEKLSSNQSFSEENNQIKDSSENKRIEELEKQIEELRASQNNQESSKEEIQKLNIDIENL 414

Query: 859  LEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLI 918
             +EN+NL+   +++    + +  + N+ +   +   K + QL++   +L++    +    
Sbjct: 415  KKENENLKKKNTELNDSVDGMNNQINKLNKENNSLQKEKKQLQEKIESLEQQQSSNDNQF 474

Query: 919  VQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNV 978
                  +E L+IE N     +  +K  LN+  +   + + QL  QL   +N  ENL   +
Sbjct: 475  DSSFASLEALKIELN----QSKAEKSALNDTIDGMGQQLDQLSQQLSSLRNENENLKKEL 530

Query: 979  EELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVS 1038
            EE         + + Q    +  D  E+ +N + K N  LK ++ E    N + N A++ 
Sbjct: 531  EEAKSNASGQQNNNDQSLNEEIQDLKEK-LNNLEKENEKLKSQESES---NNEDNKAELE 586

Query: 1039 YMSM-VSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVR----EQDDQIK 1093
             + + ++  +         +  ME ++   S+++ + ++ NE L   +R    E +D  K
Sbjct: 587  SLQLNLNQTKQDRDNLKETVNLMEGQLNGFSEKVNNLQKENENLNNKLRSSQSELEDAKK 646

Query: 1094 ELKETKLTFE-MNIP----KTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQ--- 1145
            +L E K+  E +NI     K      + TI  MSD  N +             LK Q   
Sbjct: 647  QLDENKMEVETLNIENNRLKQNNNNFNDTINGMSDQLNKISNERDAVQAENQQLKEQINN 706

Query: 1146 ------EEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQL 1199
                     E  + +   Q++S + N EL E  +K+   + +  +LT      + +IN  
Sbjct: 707  LKSNQDNSSENNENKKQKQDKSDEENDELLEAKSKLSDSQDIIQKLTVEVESLKIEINHY 766

Query: 1200 KSKLEQLNT-----EN--DNLLSTVAEL---RSSISSAVDQRGFEIAELWKQHLAQREAD 1249
            K + +  N      EN  + L S + +L      I +  +    E  EL K  L+  +  
Sbjct: 767  KQEKDNANESAKAQENKIEKLCSEIDQLCAKNKDILAENESLSNENEEL-KSKLSNFKDQ 825

Query: 1250 FQKTEH-ELRVQLSAFESKYEQLLDSVQSSTQ--EETNKIVTMEQVTSLQNK--LQDKEE 1304
             Q  ++ EL  ++SA E +  +  + ++   Q  EE+ K+ +  +   ++N   +QDK  
Sbjct: 826  TQNEKNSELEEKISALEKENSEFKNKIKQQEQQIEESEKLNSEIEALKIENNRHIQDK-- 883

Query: 1305 HLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQE 1364
               N+QE    +  Q+E L +E  D K+                  D     ++ +Q+ +
Sbjct: 884  --ANMQESANAMSQQLEKLSTENSDLKI---LQQKVLKLEEELKQKDGNNNEETLEQINK 938

Query: 1365 QSILNINEENAQLKK-----SSXXXXXXXXXXXXRVNDAEAKVL-------ELTHQLELK 1412
                ++N++N +++K     +             + +  E K++       +  HQ+E +
Sbjct: 939  LE-SDLNQKNEEIEKLIQLQNDVTDFLLVIEETNKEDSIEKKLVIAKDQVNKYKHQIE-E 996

Query: 1413 DSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANH 1472
            +S       ++   LT+ N   +       +  K +++L  E ES++A     +++    
Sbjct: 997  NSGYLDTAAKHLCKLTKENKALK--ESNSAKKVKSLQNLVSESESKIADKDKLINDLKEE 1054

Query: 1473 YETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIE 1532
             E ++ ++E            K+T S S   + +E +K  ++ +A   ++   LE +EI 
Sbjct: 1055 LEMLKSQTECP----------KMTRSKSQTVESSENDKQAKKYLALIRKLMKQLEQKEIL 1104

Query: 1533 IVTLNDEITNLQNMVRASSSKIQK 1556
            +  LN +I++++N +    S++ +
Sbjct: 1105 VENLNKQISDVKNSLETRFSQMSR 1128



 Score =  156 bits (379), Expect = 4e-36
 Identities = 237/1187 (19%), Positives = 511/1187 (43%), Gaps = 74/1187 (6%)

Query: 169  ETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAM 228
            E    +L + I ++D  +E + K                    E T  ++ +++E  +A+
Sbjct: 7    EALAAELDQTITQRDNALE-EVKNLKQQLEDSKKDVESITEDFEKTSDELEQVKEK-LAL 64

Query: 229  EAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXX 288
            + + + E Q+ +  ++ +   +S+    NK L      +  E++++ + LE+        
Sbjct: 65   KDQTEIELQKEITQLKEQIQNLSTEATNNKSLNEEIQRLKSENTEIKEALERNKTQNKEN 124

Query: 289  XXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMT-ELTKKIELLEHLNCQIRQTNKELEN 347
                  + + + E   ++ T+  E    +I ++  EL+K  +  E L     QT+ EL N
Sbjct: 125  SENEEVINQLTGEN--QKLTDENESLKSQIESLKKELSKLNQNQEELLKASGQTD-ELNN 181

Query: 348  KLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEI 407
            KL+ +  E+K+++   K      S   G    S +K+ ++ +++E      + +  K  +
Sbjct: 182  KLSNLEAENKSLTEKLKSLENENSTLLG--FVSTLKTQFNNMNTEVQRVIGNLEAEKTNL 239

Query: 408  AK-LEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLI 466
             +  E   ++ +K L D  Y  ++  +            + LI   +++ +  +E   LI
Sbjct: 240  EEEFENYKENSHKQL-DVHY--NKITSLEDEISQLKKENENLIKIKEIKEEIQVE---LI 293

Query: 467  HVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNM 526
            H+    E   ++ K  E L+ EL+    D+  K+  ++++  E QI+ L +E D  N  +
Sbjct: 294  HMKQENE---KLKKESESLQDELDTAKADLEDKE--DEIEDKENQISNLEEETDELNAKI 348

Query: 527  IKVKSN-HKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHL 585
             ++ S   KL   Q     +N  K S  NK I  L +++  L       E  K  +Q   
Sbjct: 349  EELNSTIEKLSSNQSFSEENNQIKDSSENKRIEELEKQIEELRASQNNQESSKEEIQKLN 408

Query: 586  VDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDK-- 643
            +D ++ +    ++ KK  E+ +  +     I+ L  +   L +E   LQ+K + +E +  
Sbjct: 409  IDIENLKKENENLKKKNTELNDSVDGMNNQINKLNKENNSLQKEKKQLQEKIESLEQQQS 468

Query: 644  ---------LADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYG 694
                      A +  L+ +   S+ +   L + ID +     +L+  + +L+ + E L  
Sbjct: 469  SNDNQFDSSFASLEALKIELNQSKAEKSALNDTIDGMGQQLDQLSQQLSSLRNENENLKK 528

Query: 695  TIKDLENDKEDIMNKLQNYIQENM-DLTDKLEKMSAE--KISELLAKINHEE-QSKIQT- 749
             +++ +++     N     + E + DL +KL  +  E  K+    ++ N+E+ ++++++ 
Sbjct: 529  ELEEAKSNASGQQNNNDQSLNEEIQDLKEKLNNLEKENEKLKSQESESNNEDNKAELESL 588

Query: 750  QFGIDAKIQERDLYIENI---ESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYL 806
            Q  ++   Q+RD   E +   E +L+ +  ++  L++    + ++  S + + +     L
Sbjct: 589  QLNLNQTKQDRDNLKETVNLMEGQLNGFSEKVNNLQKENENLNNKLRSSQSELEDAKKQL 648

Query: 807  QEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQ 866
             E +       I+ + L        D    +  QL +I +E   +Q +NQ L E+  NL+
Sbjct: 649  DENKMEVETLNIENNRLKQNNNNFNDTINGMSDQLNKISNERDAVQAENQQLKEQINNLK 708

Query: 867  ISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIE 926
             +  +  ++     +K +++D    E  + +++L D +  ++++T E ++L    K EI 
Sbjct: 709  SNQDNSSENNENKKQKQDKSDEENDELLEAKSKLSDSQDIIQKLTVEVESL----KIEIN 764

Query: 927  DLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEEL----- 981
              + E +   ESA    K    K EK    + QL A+ ++     E+L+   EEL     
Sbjct: 765  HYKQEKDNANESA----KAQENKIEKLCSEIDQLCAKNKDILAENESLSNENEELKSKLS 820

Query: 982  -------NKMNLELIDK--HVQKQQTQSPD---YTEQYINEINKLNALLKQKDEEIIALN 1029
                   N+ N EL +K   ++K+ ++  +     EQ I E  KLN+ ++    E     
Sbjct: 821  NFKDQTQNEKNSELEEKISALEKENSEFKNKIKQQEQQIEESEKLNSEIEALKIENNRHI 880

Query: 1030 QKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQL--LDSKQHNEELQILVRE 1087
            Q   N Q S  +M    E KL+   + L+ +++++ ++ ++L   D   + E L+ + + 
Sbjct: 881  QDKANMQESANAMSQQLE-KLSTENSDLKILQQKVLKLEEELKQKDGNNNEETLEQINKL 939

Query: 1088 QDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEE 1147
            + D  ++ +E +   ++    T+ +++    E   +D+                 +++E 
Sbjct: 940  ESDLNQKNEEIEKLIQLQNDVTDFLLVIE--ETNKEDSIEKKLVIAKDQVNKYKHQIEEN 997

Query: 1148 EEFIQERSVLQEQSAKLNTELQECYT--KIIQLETLNTELTGHDVVNQEQINQLKSKLEQ 1205
              ++   +    +  K N  L+E  +  K+  L+ L +E         + IN LK +LE 
Sbjct: 998  SGYLDTAAKHLCKLTKENKALKESNSAKKVKSLQNLVSESESKIADKDKLINDLKEELEM 1057

Query: 1206 LNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFE 1265
            L ++ +    T ++ ++  SS  D++  +   L ++ + Q E      E+ L  Q+S  +
Sbjct: 1058 LKSQTECPKMTRSKSQTVESSENDKQAKKYLALIRKLMKQLEQKEILVEN-LNKQISDVK 1116

Query: 1266 SKYEQLLDSVQSSTQEETNKI-VTMEQVTSLQNKLQDKEEHLRNLQE 1311
            +  E     +     E+ N      + +T    KL+ K   L   Q+
Sbjct: 1117 NSLETRFSQMSRVIDEKINLFEENFDNLTDSFKKLRSKVAELPQRQQ 1163



 Score =  146 bits (353), Expect = 6e-33
 Identities = 188/899 (20%), Positives = 389/899 (43%), Gaps = 68/899 (7%)

Query: 691  QLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQ 750
            +L  TI   +N  E++ N  Q       D+    E    EK S+ L ++  +   K QT+
Sbjct: 12   ELDQTITQRDNALEEVKNLKQQLEDSKKDVESITEDF--EKTSDELEQVKEKLALKDQTE 69

Query: 751  FGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQ 810
              +  +I +    I+N+ +E +  KS    L E I  ++     ++   ++  +  Q K+
Sbjct: 70   IELQKEITQLKEQIQNLSTEATNNKS----LNEEIQRLKSENTEIKEALER--NKTQNKE 123

Query: 811  KAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLE---ENQNLQI 867
             + +E  I  ++L      L D +  ++ Q+  ++ E  +L +  + LL+   +   L  
Sbjct: 124  NSENEEVI--NQLTGENQKLTDENESLKSQIESLKKELSKLNQNQEELLKASGQTDELNN 181

Query: 868  SLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIED 927
             LS+++    +L EK       E+E++     +  L++    +  E Q +I   + E  +
Sbjct: 182  KLSNLEAENKSLTEKLKSL---ENENSTLLGFVSTLKTQFNNMNTEVQRVIGNLEAEKTN 238

Query: 928  LEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLE 987
            LE EF    E++    K L+  Y K    +T LE ++ + K   ENL    E   ++ +E
Sbjct: 239  LEEEFENYKENS---HKQLDVHYNK----ITSLEDEISQLKKENENLIKIKEIKEEIQVE 291

Query: 988  LIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYE 1047
            LI  H++++  +    +E   +E++   A L+ K++EI     +I+N +        +  
Sbjct: 292  LI--HMKQENEKLKKESESLQDELDTAKADLEDKEDEIEDKENQISNLEEE----TDELN 345

Query: 1048 SKLAQFTTKLENME--EEMQRVSKQLLDSKQHN--EELQILVRE----QDDQIKELKET- 1098
            +K+ +  + +E +   +     + Q+ DS ++   EEL+  + E    Q++Q    +E  
Sbjct: 346  AKIEELNSTIEKLSSNQSFSEENNQIKDSSENKRIEELEKQIEELRASQNNQESSKEEIQ 405

Query: 1099 KLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQER-SVL 1157
            KL  ++   K E   +      ++D  + ++            L  Q+E++ +QE+   L
Sbjct: 406  KLNIDIENLKKENENLKKKNTELNDSVDGMNNQINKLNKENNSL--QKEKKQLQEKIESL 463

Query: 1158 QEQSAKLNTELQECYTKIIQLET-LNTELTGHDVVNQ------EQINQLKSKLEQLNTEN 1210
            ++Q +  + +    +  +  L+  LN        +N       +Q++QL  +L  L  EN
Sbjct: 464  EQQQSSNDNQFDSSFASLEALKIELNQSKAEKSALNDTIDGMGQQLDQLSQQLSSLRNEN 523

Query: 1211 DNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQ 1270
            +NL   + E +S+ S   +     + E   Q L ++  + +K   +L+ Q S   ++  +
Sbjct: 524  ENLKKELEEAKSNASGQQNNNDQSLNEEI-QDLKEKLNNLEKENEKLKSQESESNNEDNK 582

Query: 1271 L-LDSVQSS-TQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIE 1328
              L+S+Q +  Q + ++    E V  ++ +L    E + NLQ++  ++ N++   +SE+E
Sbjct: 583  AELESLQLNLNQTKQDRDNLKETVNLMEGQLNGFSEKVNNLQKENENLNNKLRSSQSELE 642

Query: 1329 DEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXX 1388
            D K                    L  EN   KQ        IN  + QL K S       
Sbjct: 643  DAKKQLDENKMEVET--------LNIENNRLKQNNNNFNDTINGMSDQLNKISNERDAVQ 694

Query: 1389 XXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRI 1448
                   N    + +      +   SE  +   +      + NDE    + +L + +  I
Sbjct: 695  AE-----NQQLKEQINNLKSNQDNSSENNENKKQKQDKSDEENDELLEAKSKLSDSQDII 749

Query: 1449 EDLTYEKES-ELAILRLKMHENANHYETMQKESEIERV-KLIEELNVKITESVSLNKQVA 1506
            + LT E ES ++ I   K  ++  +     +E++IE++   I++L  K  + ++ N+ ++
Sbjct: 750  QKLTVEVESLKIEINHYKQEKDNANESAKAQENKIEKLCSEIDQLCAKNKDILAENESLS 809

Query: 1507 ELNKALEEEVAKTNEMQTALENQEIE--IVTLNDEITNLQNMVRASSSKIQKHVSFASD 1563
              N+ L+ +++   +     +N E+E  I  L  E +  +N ++    +I++     S+
Sbjct: 810  NENEELKSKLSNFKDQTQNEKNSELEEKISALEKENSEFKNKIKQQEQQIEESEKLNSE 868



 Score =  130 bits (315), Expect = 2e-28
 Identities = 217/1051 (20%), Positives = 469/1051 (44%), Gaps = 112/1051 (10%)

Query: 610  ETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQS--DQVCSEIKS--VHLE 665
            +  L+ +  L+ Q  D  +++  + + +++  D+L  + +  +  DQ   E++     L+
Sbjct: 21   DNALEEVKNLKQQLEDSKKDVESITEDFEKTSDELEQVKEKLALKDQTEIELQKEITQLK 80

Query: 666  EQIDALSA---SKKELALVIENLKLDKEQLYGTIK-----DLEN-DKEDIMNKLQNYIQE 716
            EQI  LS    + K L   I+ LK +  ++   ++     + EN + E+++N+L     E
Sbjct: 81   EQIQNLSTEATNNKSLNEEIQRLKSENTEIKEALERNKTQNKENSENEEVINQLTG---E 137

Query: 717  NMDLTDKLEKMSA--EKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKY 774
            N  LTD+ E + +  E + + L+K+N  ++  ++     D    E +  + N+E+E    
Sbjct: 138  NQKLTDENESLKSQIESLKKELSKLNQNQEELLKASGQTD----ELNNKLSNLEAENKSL 193

Query: 775  KSRICRLEESIAVMEDRRYSLERKADQLGSYLQEK-QKAYSEYTIQEDELVNRLAVLMDH 833
              ++  LE   + +     +L+ + + + + +Q       +E T  E+E  N        
Sbjct: 194  TEKLKSLENENSTLLGFVSTLKTQFNNMNTEVQRVIGNLEAEKTNLEEEFENYKENSHKQ 253

Query: 834  DRVVEKQLLEIEHENKELQKKNQILL---EENQNLQISLSDMQQHYNALVEKA----NRT 886
              V   ++  +E E  +L+K+N+ L+   E  + +Q+ L  M+Q    L +++    +  
Sbjct: 254  LDVHYNKITSLEDEISQLKKENENLIKIKEIKEEIQVELIHMKQENEKLKKESESLQDEL 313

Query: 887  DLAESESTKYQTQLRDLE---SNLKRITHEHQTLIVQKKKEIEDLEI-----EFNTQIES 938
            D A+++    + ++ D E   SNL+  T E    I +    IE L       E N QI+ 
Sbjct: 314  DTAKADLEDKEDEIEDKENQISNLEEETDELNAKIEELNSTIEKLSSNQSFSEENNQIKD 373

Query: 939  AIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQT 998
            +  +K++  E+ EK IE +   +   +  K  I+ LN+++E L K N  L  K+ +    
Sbjct: 374  SSENKRI--EELEKQIEELRASQNNQESSKEEIQKLNIDIENLKKENENLKKKNTELND- 430

Query: 999  QSPDYTEQYINEINKLNALL----KQKDEEIIALNQKI----NNAQVSYMSM------VS 1044
             S D     IN++NK N  L    KQ  E+I +L Q+     N    S+ S+      ++
Sbjct: 431  -SVDGMNNQINKLNKENNSLQKEKKQLQEKIESLEQQQSSNDNQFDSSFASLEALKIELN 489

Query: 1045 DYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQ---------------D 1089
              +++ +     ++ M +++ ++S+QL   +  NE L+  + E                +
Sbjct: 490  QSKAEKSALNDTIDGMGQQLDQLSQQLSSLRNENENLKKELEEAKSNASGQQNNNDQSLN 549

Query: 1090 DQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLK----VQ 1145
            ++I++LKE     E    K +     S  E    +  ++             LK    + 
Sbjct: 550  EEIQDLKEKLNNLEKENEKLKSQESESNNEDNKAELESLQLNLNQTKQDRDNLKETVNLM 609

Query: 1146 EEE--EFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKL 1203
            E +   F ++ + LQ+++  LN +L+   +   +LE    +L   + +  E +N   ++L
Sbjct: 610  EGQLNGFSEKVNNLQKENENLNNKLRSSQS---ELEDAKKQLD-ENKMEVETLNIENNRL 665

Query: 1204 EQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQ--HLAQREADFQKTEHELRVQL 1261
            +Q N   ++ ++ +++  + IS+  D    E  +L +Q  +L   + +  +     + + 
Sbjct: 666  KQNNNNFNDTINGMSDQLNKISNERDAVQAENQQLKEQINNLKSNQDNSSENNENKKQKQ 725

Query: 1262 SAFESKYEQLLD--SVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQ 1319
               + + ++LL+  S  S +Q+   K+    +V SL+ ++   ++   N  E      N+
Sbjct: 726  DKSDEENDELLEAKSKLSDSQDIIQKLTV--EVESLKIEINHYKQEKDNANESAKAQENK 783

Query: 1320 IEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYK-QMQEQSILNINEENAQLK 1378
            IE L SEI D+  A                 +L+++  ++K Q Q +    + E+ + L+
Sbjct: 784  IEKLCSEI-DQLCAKNKDILAENESLSNENEELKSKLSNFKDQTQNEKNSELEEKISALE 842

Query: 1379 KSSXXXXXXXXXXXXRVNDAEA-----KVLELTHQLELKDSEIYQKT----HEYTITLTQ 1429
            K +            ++ ++E      + L++ +   ++D    Q++     +    L+ 
Sbjct: 843  KENSEFKNKIKQQEQQIEESEKLNSEIEALKIENNRHIQDKANMQESANAMSQQLEKLST 902

Query: 1430 RNDEFENVRQQLVEYEKRIE--DLTYEKESELAILRLKMHENANHYET---MQKESEI-E 1483
             N + + ++Q++++ E+ ++  D    +E+   I +L+   N  + E    +Q ++++ +
Sbjct: 903  ENSDLKILQQKVLKLEEELKQKDGNNNEETLEQINKLESDLNQKNEEIEKLIQLQNDVTD 962

Query: 1484 RVKLIEELNVK--ITESVSLNK-QVAELNKALEE-----EVAKTNEMQTALENQEIEIVT 1535
             + +IEE N +  I + + + K QV +    +EE     + A  +  +   EN+ ++   
Sbjct: 963  FLLVIEETNKEDSIEKKLVIAKDQVNKYKHQIEENSGYLDTAAKHLCKLTKENKALKESN 1022

Query: 1536 LNDEITNLQNMVRASSSKIQKHVSFASDTKQ 1566
               ++ +LQN+V  S SKI       +D K+
Sbjct: 1023 SAKKVKSLQNLVSESESKIADKDKLINDLKE 1053



 Score = 81.0 bits (191), Expect = 2e-13
 Identities = 142/663 (21%), Positives = 276/663 (41%), Gaps = 61/663 (9%)

Query: 954  IEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINK 1013
            +E V  L+ QL++ K ++E++  + E+ +    ++ +K   K QT+      +   EI +
Sbjct: 24   LEEVKNLKQQLEDSKKDVESITEDFEKTSDELEQVKEKLALKDQTEI-----ELQKEITQ 78

Query: 1014 LNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEE-EMQRVSKQLL 1072
            L   ++    E  A N K  N ++  +    + E K A    K +N E  E + V  QL 
Sbjct: 79   LKEQIQNLSTE--ATNNKSLNEEIQRLKS-ENTEIKEALERNKTQNKENSENEEVINQLT 135

Query: 1073 DSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXX 1132
                 N++L         QI+ LK  K   ++N  + E +  S   + +++  +N++   
Sbjct: 136  GE---NQKLTDENESLKSQIESLK--KELSKLNQNQEELLKASGQTDELNNKLSNLEAEN 190

Query: 1133 XXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKI------IQLETLNTELT 1186
                     L+  E    +   S L+ Q   +NTE+Q     +      ++ E  N +  
Sbjct: 191  KSLTEKLKSLE-NENSTLLGFVSTLKTQFNNMNTEVQRVIGNLEAEKTNLEEEFENYKEN 249

Query: 1187 GHDV--VNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLA 1244
             H    V+  +I  L+ ++ QL  EN+NL+  + E++  I         E+  + KQ   
Sbjct: 250  SHKQLDVHYNKITSLEDEISQLKKENENLIK-IKEIKEEIQ-------VELIHM-KQENE 300

Query: 1245 QREADFQKTEHELRVQLSAFESKYEQLLDSVQ--SSTQEETNKI-VTMEQVTSLQNKLQD 1301
            + + + +  + EL    +  E K +++ D     S+ +EET+++   +E++ S   KL  
Sbjct: 301  KLKKESESLQDELDTAKADLEDKEDEIEDKENQISNLEEETDELNAKIEELNSTIEKLSS 360

Query: 1302 KEEHLR-NLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXX--DLRTENQS 1358
             +     N Q K +    +IE L  +IE+ + +                   +L+ EN++
Sbjct: 361  NQSFSEENNQIKDSSENKRIEELEKQIEELRASQNNQESSKEEIQKLNIDIENLKKENEN 420

Query: 1359 YKQMQEQ---SILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSE 1415
             K+   +   S+  +N +  +L K +            ++   E +     +Q +   + 
Sbjct: 421  LKKKNTELNDSVDGMNNQINKLNKENNSLQKEKKQLQEKIESLEQQQSSNDNQFDSSFAS 480

Query: 1416 IYQKTHEYTITLTQR---NDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANH 1472
            +     E   +  ++   ND  + + QQL +  +++  L  E E+    L  +   NA+ 
Sbjct: 481  LEALKIELNQSKAEKSALNDTIDGMGQQLDQLSQQLSSLRNENENLKKELE-EAKSNASG 539

Query: 1473 YETMQKESEIERVK-LIEELNVKITESVSLNKQVAELNKA---LEEEVAKTNEMQTALEN 1528
             +    +S  E ++ L E+LN    E+  L  Q +E N      E E  + N  QT  + 
Sbjct: 540  QQNNNDQSLNEEIQDLKEKLNNLEKENEKLKSQESESNNEDNKAELESLQLNLNQTKQDR 599

Query: 1529 QEI-EIVTL--------NDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKE 1579
              + E V L        ++++ NLQ      ++K++   S   D K+  DE   N M  E
Sbjct: 600  DNLKETVNLMEGQLNGFSEKVNNLQKENENLNNKLRSSQSELEDAKKQLDE---NKMEVE 656

Query: 1580 LLD 1582
             L+
Sbjct: 657  TLN 659



 Score = 59.3 bits (137), Expect = 9e-07
 Identities = 77/396 (19%), Positives = 166/396 (41%), Gaps = 19/396 (4%)

Query: 1191 VNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFE-IAELWKQHLAQREAD 1249
            ++  +   L ++L+Q  T+ DN L  V  L+  +  +  ++  E I E +++   + E  
Sbjct: 1    MSDSEFEALAAELDQTITQRDNALEEVKNLKQQLEDS--KKDVESITEDFEKTSDELEQV 58

Query: 1250 FQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHL-RN 1308
             +K   + + ++   + +  QL + +Q+ + E TN     E++  L+++  + +E L RN
Sbjct: 59   KEKLALKDQTEIE-LQKEITQLKEQIQNLSTEATNNKSLNEEIQRLKSENTEIKEALERN 117

Query: 1309 LQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSIL 1368
              +   +  N+  I +   E++K+                      +NQ           
Sbjct: 118  KTQNKENSENEEVINQLTGENQKLTDENESLKSQIESLKKELSKLNQNQEELLKASGQTD 177

Query: 1369 NINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLT 1428
             +N + + L+  +              +     V  L  Q    ++E+ +         T
Sbjct: 178  ELNNKLSNLEAENKSLTEKLKSLENENSTLLGFVSTLKTQFNNMNTEVQRVIGNLEAEKT 237

Query: 1429 QRNDEFENVRQQLVEYEKRIEDLTYEK----ESELAILRLKMHENANHYETMQKESEIER 1484
               +EFEN ++      K++ D+ Y K    E E++ L+ K +EN    + +++E ++E 
Sbjct: 238  NLEEEFENYKE---NSHKQL-DVHYNKITSLEDEISQLK-KENENLIKIKEIKEEIQVEL 292

Query: 1485 VKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQ 1544
            + + +E      ES SL  ++      LE++  +  + +  + N E E   LN +I  L 
Sbjct: 293  IHMKQENEKLKKESESLQDELDTAKADLEDKEDEIEDKENQISNLEEETDELNAKIEELN 352

Query: 1545 NMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKEL 1580
            + +     K+  + SF+ +  Q +D   +N   +EL
Sbjct: 353  STI----EKLSSNQSFSEENNQIKDSS-ENKRIEEL 383



 Score = 46.0 bits (104), Expect = 0.009
 Identities = 103/478 (21%), Positives = 186/478 (38%), Gaps = 55/478 (11%)

Query: 151  IKEKDNALSVLQVKMKIMETTILDLQEKINEK-DQIIEAKNKATTXXXXXXXXXXXXXXX 209
            +KE+ N L   Q             Q+K +E+ D+++EAK+K +                
Sbjct: 700  LKEQINNLKSNQDNSSENNENKKQKQDKSDEENDELLEAKSKLSDSQDIIQKLTVEVESL 759

Query: 210  XXE--------DTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLE 261
              E        D   +  K QEN I       D+     KDI +++  +S+  E  K  +
Sbjct: 760  KIEINHYKQEKDNANESAKAQENKIEKLCSEIDQLCAKNKDILAENESLSNENEELKS-K 818

Query: 262  AARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIE-EKGSLEIAN 320
             + F+   ++ K + ELE+                KQ  E   EE  ++  E  +L+I N
Sbjct: 819  LSNFKDQTQNEKNS-ELEEKISALEKENSEFKNKIKQQ-EQQIEESEKLNSEIEALKIEN 876

Query: 321  MTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTA- 379
               +  K  + E  N   +Q    LE KL+T  ++ K +     K    + +K G N   
Sbjct: 877  NRHIQDKANMQESANAMSQQ----LE-KLSTENSDLKILQQKVLKLEEELKQKDGNNNEE 931

Query: 380  -----SKMKSPWSQLSSET------LNQDTDKKINKNEIAKLEMVIQSL--NKDLVDK-E 425
                 +K++S  +Q + E        N  TD  +   E  K + + + L   KD V+K +
Sbjct: 932  TLEQINKLESDLNQKNEEIEKLIQLQNDVTDFLLVIEETNKEDSIEKKLVIAKDQVNKYK 991

Query: 426  YVISEK----DTXXXXXXXXXXGKDTLI---AQLQLEHQQHMEGPSLIHVGTNTEDVNEI 478
            + I E     DT              L    +  +++  Q++   S   +    + +N++
Sbjct: 992  HQIEENSGYLDTAAKHLCKLTKENKALKESNSAKKVKSLQNLVSESESKIADKDKLINDL 1051

Query: 479  AKVQEQLK-------------QELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKN 525
             +  E LK             Q +     D   K  +  ++   +Q+ Q    ++  NK 
Sbjct: 1052 KEELEMLKSQTECPKMTRSKSQTVESSENDKQAKKYLALIRKLMKQLEQKEILVENLNKQ 1111

Query: 526  MIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQL 583
            +  VK++ + +  QM + ID    + + N +   LT+    L  KVAEL + + ++ L
Sbjct: 1112 ISDVKNSLETRFSQMSRVIDEKINLFEENFD--NLTDSFKKLRSKVAELPQRQQSISL 1167



 Score = 42.7 bits (96), Expect = 0.080
 Identities = 69/335 (20%), Positives = 141/335 (42%), Gaps = 25/335 (7%)

Query: 1265 ESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILR 1324
            +S++E L   +  +  +  N    +E+V +L+ +L+D ++ + ++ E +    +++E ++
Sbjct: 3    DSEFEALAAELDQTITQRDN---ALEEVKNLKQQLEDSKKDVESITEDFEKTSDELEQVK 59

Query: 1325 SEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKS---S 1381
             ++   K                   +L TE  + K + E+ I  +  EN ++K++   +
Sbjct: 60   EKLA-LKDQTEIELQKEITQLKEQIQNLSTEATNNKSLNEE-IQRLKSENTEIKEALERN 117

Query: 1382 XXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQL 1441
                         +N    +  +LT + E   S+I     E +  L Q  +E      Q 
Sbjct: 118  KTQNKENSENEEVINQLTGENQKLTDENESLKSQIESLKKELS-KLNQNQEELLKASGQT 176

Query: 1442 VEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSL 1501
             E   ++ +L  E E++    +LK  EN N   T+       + +    +N ++   +  
Sbjct: 177  DELNNKLSNL--EAENKSLTEKLKSLENEN--STLLGFVSTLKTQ-FNNMNTEVQRVIG- 230

Query: 1502 NKQVAELNKALEEEVAKTNE-MQTALENQEIEIVTLNDEITNL----QNMVRASSSKIQK 1556
            N +  + N  LEEE     E     L+    +I +L DEI+ L    +N+++    K + 
Sbjct: 231  NLEAEKTN--LEEEFENYKENSHKQLDVHYNKITSLEDEISQLKKENENLIKIKEIKEEI 288

Query: 1557 HVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDL 1591
             V      KQ  +E+L    ++ L D +  A+ DL
Sbjct: 289  QVELI-HMKQ-ENEKLKKE-SESLQDELDTAKADL 320


>UniRef50_UPI00006CC2B2 Cluster: hypothetical protein TTHERM_00661480;
            n=1; Tetrahymena thermophila SB210|Rep: hypothetical
            protein TTHERM_00661480 - Tetrahymena thermophila SB210
          Length = 1613

 Score =  157 bits (381), Expect = 2e-36
 Identities = 238/1171 (20%), Positives = 515/1171 (43%), Gaps = 115/1171 (9%)

Query: 471  NTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKL--------KSAEEQITQLNDEIDAA 522
            N E  N+++       Q  N E+  VN+ +++E L        KS  +QI +  + ID  
Sbjct: 423  NIESNNQLSSDANLGLQFNNQEVSQVNISEILESLNSQIQFIIKSLPDQIAKETEFIDFE 482

Query: 523  NKNMIKVKSNHKLKLKQMQKTI-DNFSKVSDSNKEIVR-----LTEELHHLSQKVAELEE 576
                 +++    L  +++ K + +   K +  N +I+R       E++  L+    +L +
Sbjct: 483  EIES-RIQEQASLNAEKIFKQLKEEIFKQNKLNTKIIRRMQNSYEEQIRQLTHDYMDLMD 541

Query: 577  EKGNLQLHLVDYDS-GRMIESDVY----KKMIEMENLAETRLKAISLLESQKFDLVQELH 631
            +    + HL++ ++    I+S V     K+  +++ L    +K   ++  Q    ++ + 
Sbjct: 542  QSIAQERHLIEDETLNSTIDSSVIEFCSKQSEKIKQLQTELMKKQCMMGKQDNKNMEVIK 601

Query: 632  ILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQ 691
             +  K +++E+KL   + ++ +     ++ ++  +Q+  LS   +E A  +  +K    Q
Sbjct: 602  NMVDKINQLENKLLKYTDMELEN--ENLQKIN--QQLQKLSKQSQEQAAKVFGIKHQNMQ 657

Query: 692  LYGTIKDLENDKEDIMNKLQNYIQENMDLTDK---LEKMSAEKISELLAKINHEEQSKIQ 748
               TI   +   E I ++ Q     + ++T K   + ++ A+  +  L  I++E++ +I 
Sbjct: 658  SISTIN--QQLAEQIHSRQQLIDTLHQEITQKNRAIHELQAKNTN--LQNISYEKEERIT 713

Query: 749  TQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMED----RRYSLERKADQLGS 804
                I   ++E++L I ++  + S     I RL++++  ++D    ++  +    + L +
Sbjct: 714  ELQNI---LEEKELEINDLNKKESLLNEDIMRLKDTLVAIQDELIAKKQEISHHINDL-T 769

Query: 805  YLQEKQKAYSEYTIQ-EDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQ 863
             LQEK + Y +      +ELVN      ++   VE+++ ++  E KE+  +   L E+  
Sbjct: 770  QLQEKNENYEQIEQNMNEELVNLQLEYNNYREEVEEKIEKLTLEIKEINLQKDELQEQLD 829

Query: 864  NLQISLSDMQQHYNALVEKA------NRTDLAESESTKY-----QTQLRDLESNLKRITH 912
             +Q     + +  + L+++       N+T + E E+ +      QT +   +    +   
Sbjct: 830  QIQTQKQSLSEERDVLIQEKEDLIQNNQTLIQEKENLQVEIESLQTSMEQQKDAFDKEID 889

Query: 913  EHQTLIVQ--KKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNN 970
              + +++Q  +K    D +   + Q        ++LN+K  +       LE +++    +
Sbjct: 890  AFEEIVLQIIEKGSSGDQDHHASLQQPKLTSLIEILNKKMVEVQSQKEHLEQEMKYLNQD 949

Query: 971  IENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQ 1030
            IEN  M VE+L     +  D   +++   + +Y +  + E  ++  LL++K +++  L +
Sbjct: 950  IENEKMTVEQL----YQECDNLAEEKNIMAQNY-DNALAEKKQVCELLEEKTQQLRELQE 1004

Query: 1031 KINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDD 1090
            K  N +  +    +  + K AQ   +LEN  +E+ + ++++  + +  E++ +L  E+++
Sbjct: 1005 KEQNKENDFQHFENQIKEKEAQIL-ELENKLQEINKTTEEV--NSELKEKIDVL-HEKEE 1060

Query: 1091 QIKELKET--KLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEE 1148
             IK LKE+      + N   +E   I   I  M +D    +            L  Q +E
Sbjct: 1061 TIKILKESLDNYNIKYNTKVSELQEIHDYISQMQNDIKQKEAQIEESNQLNQQLSNQYQE 1120

Query: 1149 EFIQERSVLQEQSAKLNT------ELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSK 1202
              IQ  +++ +     N       ++QE    I  L      L+     NQE IN  K K
Sbjct: 1121 LQIQNENLIYQNQNNFNQVDLLSKQIQEQNQLIEDLNLEKNTLSTTLFSNQELINSYKLK 1180

Query: 1203 LEQL-------NTENDNLLSTVAELRSSISSA---VDQRGFEIA--ELWKQHLAQREA-- 1248
            LE+L       NT        +AEL S++S       Q+  E+   +L+++ ++  +   
Sbjct: 1181 LEELQQAFEFNNTTISEYEKQIAELNSTVSQLNLLCQQKDSELQNYKLYEEKISNHQLID 1240

Query: 1249 --DFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQV-TSLQNKLQ----D 1301
              ++ + E ELR ++     +  +L       T E  NKI+T+E + T L ++++    +
Sbjct: 1241 KEEYDRKEKELREKIENLSKEIYELNRQNDEQTNEFANKIITLESLNTDLNDQMEQIRSE 1300

Query: 1302 KEEHLRNLQEKY----ADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQ 1357
            K++ ++ ++EKY    ++   QIE L+S+++ EK                   +   EN 
Sbjct: 1301 KDKQIQLVKEKYQQLESEYRGQIEELQSQLKWEK-QINEDSDLHSNKKLEENYEFN-ENS 1358

Query: 1358 SYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSE-- 1415
            +  Q++  ++ + N ++++ +  S            RVN  E ++++L + L+   +   
Sbjct: 1359 AEGQVRSGNLGSQNNQDSRQELDSYKE---------RVNILEVQIIKLKNDLQTSQNTNT 1409

Query: 1416 -IYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESEL-AILRLKMHENANHY 1473
             I ++      T      E +++  +L   +K+   L  E E ++ +I   K H   N  
Sbjct: 1410 VIERQIKGLHSTNENFAKEIDSLLIKLDNEQKKYIALQKETEEQIESITDEKRHLKMNFD 1469

Query: 1474 ETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALE-EEVAKTNEMQTALENQEIE 1532
            E ++K +E E  + + +L  +I    SL  Q  +L K L   +V    E Q++++ Q   
Sbjct: 1470 ELLEKMNESENFERLNQLQKEID---SLKIQNEQLQKQLSLPQVGSQIERQSSIQIQNQG 1526

Query: 1533 IVTLNDEITNLQNMVRASSSKIQKHVSFASD 1563
             V    E  N+    + S S+    ++  +D
Sbjct: 1527 QVVQKSE-QNVDKPAKKSGSEEIHEINLVND 1556



 Score =  120 bits (288), Expect = 4e-25
 Identities = 235/1149 (20%), Positives = 483/1149 (42%), Gaps = 86/1149 (7%)

Query: 468  VGTNTEDVNE-IAKVQEQLKQELNDEIKDVNVKDLIEKL-KSAEEQITQLNDEIDAANKN 525
            + TN +D +   +K  E+ + + ND      +   I+ + K  + + +Q+N E  + +  
Sbjct: 234  ISTNDDDDDVGFSKKTEKKESKNNDAANQSGLLSKIKNIFKKEDSRASQVNLEGVSNDFR 293

Query: 526  MIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGN-LQLH 584
               +K     + ++    +D    +   N+      +   + S          G+  Q  
Sbjct: 294  YCPIKKQWIFEGQEENSVLDEPPPIIPVNQGAANAQQSDQNNSVAADNSVSNLGSGAQTP 353

Query: 585  LVDYDSGRMIESDV-YKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDK 643
               YD  + +   V Y+   +++  A+ + K      +  F   Q++      YD   + 
Sbjct: 354  SQAYDPKQALTRPVNYRNARDLKAKAKEKEKQKPRPAAFNFMQQQKVEENMSNYDSTANN 413

Query: 644  LADISQ-LQSDQVCSEIKS-VHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKD-LE 700
                 Q +Q+ +  +++ S  +L  Q +    S+  ++ ++E+L    + +  ++ D + 
Sbjct: 414  FDSTEQNIQNIESNNQLSSDANLGLQFNNQEVSQVNISEILESLNSQIQFIIKSLPDQIA 473

Query: 701  NDKEDI-MNKLQNYIQENMDLT-DKLEKMSAEKI---SELLAKINHEEQSKIQTQFGIDA 755
             + E I   ++++ IQE   L  +K+ K   E+I   ++L  KI    Q+  + Q     
Sbjct: 474  KETEFIDFEEIESRIQEQASLNAEKIFKQLKEEIFKQNKLNTKIIRRMQNSYEEQIR-QL 532

Query: 756  KIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSE 815
                 DL  ++I  E    +          +V+E      E K  QL + L +KQ    +
Sbjct: 533  THDYMDLMDQSIAQERHLIEDETLNSTIDSSVIEFCSKQSE-KIKQLQTELMKKQCMMGK 591

Query: 816  YTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQH 875
               +  E++  +   +D    +E +LL+  + + EL+ +N  L + NQ LQ  LS   Q 
Sbjct: 592  QDNKNMEVIKNM---VDKINQLENKLLK--YTDMELENEN--LQKINQQLQ-KLSKQSQE 643

Query: 876  YNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQ 935
              A V      ++ +S ST  Q     + S  + I   HQ  I QK + I +L+ + NT 
Sbjct: 644  QAAKVFGIKHQNM-QSISTINQQLAEQIHSRQQLIDTLHQE-ITQKNRAIHELQAK-NTN 700

Query: 936  IESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHV-- 993
            ++         N  YEK  E +T+L+  L+E +  I +LN     LN+  + L D  V  
Sbjct: 701  LQ---------NISYEKE-ERITELQNILEEKELEINDLNKKESLLNEDIMRLKDTLVAI 750

Query: 994  QKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQF 1053
            Q +          +IN++ +L    +  ++    +N+++ N Q+ Y +   + E K+ + 
Sbjct: 751  QDELIAKKQEISHHINDLTQLQEKNENYEQIEQNMNEELVNLQLEYNNYREEVEEKIEKL 810

Query: 1054 TTKLENM---EEEMQRVSKQLLDSKQH-NEELQILVREQDDQIKELKETKLTFEMNIPKT 1109
            T +++ +   ++E+Q    Q+   KQ  +EE  +L++E++D I+   +T +  + N+ + 
Sbjct: 811  TLEIKEINLQKDELQEQLDQIQTQKQSLSEERDVLIQEKEDLIQN-NQTLIQEKENL-QV 868

Query: 1110 EGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQ 1169
            E   + +++E   D  +               L++ E+     +      Q  KL + ++
Sbjct: 869  EIESLQTSMEQQKDAFDK-----EIDAFEEIVLQIIEKGSSGDQDHHASLQQPKLTSLIE 923

Query: 1170 ECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVD 1229
                K++++++    L        + I   K  +EQL  E DNL      +  +  +A+ 
Sbjct: 924  ILNKKMVEVQSQKEHLEQEMKYLNQDIENEKMTVEQLYQECDNLAEEKNIMAQNYDNALA 983

Query: 1230 QRG--FEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIV 1287
            ++    E+ E   Q L + +   Q  E++ +   +  + K  Q+L+ +++  QE  NK  
Sbjct: 984  EKKQVCELLEEKTQQLRELQEKEQNKENDFQHFENQIKEKEAQILE-LENKLQE-INK-- 1039

Query: 1288 TMEQVTS-LQNK---LQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXX 1343
            T E+V S L+ K   L +KEE ++ L+E   +   +     SE+++              
Sbjct: 1040 TTEEVNSELKEKIDVLHEKEETIKILKESLDNYNIKYNTKVSELQE----IHDYISQMQN 1095

Query: 1344 XXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVL 1403
                    +   NQ  +Q+  Q    +  +N  L   +            ++ +    + 
Sbjct: 1096 DIKQKEAQIEESNQLNQQLSNQ-YQELQIQNENLIYQNQNNFNQVDLLSKQIQEQNQLIE 1154

Query: 1404 ELTHQLELKDSEIYQKT---HEYTITLTQRNDEFENVRQQLVEYEKRIEDLT-------- 1452
            +L  +     + ++      + Y + L +    FE     + EYEK+I +L         
Sbjct: 1155 DLNLEKNTLSTTLFSNQELINSYKLKLEELQQAFEFNNTTISEYEKQIAELNSTVSQLNL 1214

Query: 1453 --YEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNK 1510
               +K+SEL   +L   + +NH + + KE E +R +  +EL  KI    +L+K++ ELN+
Sbjct: 1215 LCQQKDSELQNYKLYEEKISNH-QLIDKE-EYDRKE--KELREKIE---NLSKEIYELNR 1267

Query: 1511 ALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDE 1570
              +E+   TNE    +   E     LND++  +++        +++         +G+ E
Sbjct: 1268 QNDEQ---TNEFANKIITLESLNTDLNDQMEQIRSEKDKQIQLVKEKYQQLESEYRGQIE 1324

Query: 1571 QLDNTMNKE 1579
            +L + +  E
Sbjct: 1325 ELQSQLKWE 1333



 Score =  103 bits (248), Expect = 3e-20
 Identities = 210/1167 (17%), Positives = 488/1167 (41%), Gaps = 98/1167 (8%)

Query: 388  QLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDT 447
            Q +++ ++Q    +I ++  ++++ +I+SL   +  +   I  ++             + 
Sbjct: 439  QFNNQEVSQVNISEILESLNSQIQFIIKSLPDQIAKETEFIDFEEIESRIQEQASLNAEK 498

Query: 448  LIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKS 507
            +  QL+ E  +  +         NT+ +  +    E+  ++L  +  D+  + + ++   
Sbjct: 499  IFKQLKEEIFKQNK--------LNTKIIRRMQNSYEEQIRQLTHDYMDLMDQSIAQERHL 550

Query: 508  AEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDN----FSKVSDSNKEIVR-LTE 562
             E++   LN  ID++   +I+  S    K+KQ+Q  +        K  + N E+++ + +
Sbjct: 551  IEDET--LNSTIDSS---VIEFCSKQSEKIKQLQTELMKKQCMMGKQDNKNMEVIKNMVD 605

Query: 563  ELHHLSQKVAELEE-EKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLES 621
            +++ L  K+ +  + E  N  L  ++    ++ +    ++  ++  +    +++IS +  
Sbjct: 606  KINQLENKLLKYTDMELENENLQKINQQLQKLSKQS-QEQAAKVFGIKHQNMQSISTINQ 664

Query: 622  QKFDLVQELHILQQKYD----EVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKE 677
            Q   L +++H  QQ  D    E+  K   I +LQ+     +  S   EE+I  L    +E
Sbjct: 665  Q---LAEQIHSRQQLIDTLHQEITQKNRAIHELQAKNTNLQNISYEKEERITELQNILEE 721

Query: 678  LALVIENLKLDKEQLYGTIKDLEND----KEDIMNKLQNYIQENMDLTDKLEKMSAEKIS 733
              L I +L   +  L   I  L++     +++++ K Q       DLT   EK   E   
Sbjct: 722  KELEINDLNKKESLLNEDIMRLKDTLVAIQDELIAKKQEISHHINDLTQLQEKN--ENYE 779

Query: 734  ELLAKINHEEQSKIQTQFG-----IDAKIQERDLYIENIESELSKYKSRICRLE-ESIAV 787
            ++   +N EE   +Q ++      ++ KI++  L I+ I  +  + + ++ +++ +  ++
Sbjct: 780  QIEQNMN-EELVNLQLEYNNYREEVEEKIEKLTLEIKEINLQKDELQEQLDQIQTQKQSL 838

Query: 788  MEDRRYSLERKADQLGS---YLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEI 844
             E+R   ++ K D + +    +QEK+    E    +  +  +           E+ +L+I
Sbjct: 839  SEERDVLIQEKEDLIQNNQTLIQEKENLQVEIESLQTSMEQQKDAFDKEIDAFEEIVLQI 898

Query: 845  ---------EHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTK 895
                     +H     Q K   L+E      + +   ++H    ++  N+    E  + +
Sbjct: 899  IEKGSSGDQDHHASLQQPKLTSLIEILNKKMVEVQSQKEHLEQEMKYLNQDIENEKMTVE 958

Query: 896  YQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIE 955
               Q  D  +  K I  ++    + +KK++ +L +E  TQ    +++K+   E   ++ E
Sbjct: 959  QLYQECDNLAEEKNIMAQNYDNALAEKKQVCEL-LEEKTQQLRELQEKEQNKENDFQHFE 1017

Query: 956  -YVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKL 1014
              + + EAQ+ E +N ++ +N   EE+N    E ID   +K++T      +     ++  
Sbjct: 1018 NQIKEKEAQILELENKLQEINKTTEEVNSELKEKIDVLHEKEET-----IKILKESLDNY 1072

Query: 1015 NALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDS 1074
            N     K  E+  ++  I+  Q       +  E    Q   +L N  +E+Q  ++ L+  
Sbjct: 1073 NIKYNTKVSELQEIHDYISQMQNDIKQKEAQIEES-NQLNQQLSNQYQELQIQNENLIYQ 1131

Query: 1075 KQHN-EELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANN--VDXX 1131
             Q+N  ++ +L +    QI+E  + +L  ++N+ K     +S+T+    +  N+  +   
Sbjct: 1132 NQNNFNQVDLLSK----QIQE--QNQLIEDLNLEKN---TLSTTLFSNQELINSYKLKLE 1182

Query: 1132 XXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVV 1191
                        + E E+ I E   L    ++LN   Q+  +++   +    +++ H ++
Sbjct: 1183 ELQQAFEFNNTTISEYEKQIAE---LNSTVSQLNLLCQQKDSELQNYKLYEEKISNHQLI 1239

Query: 1192 NQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQ 1251
            ++E+ ++   K ++L  + +NL   + EL        ++   +I  L   +    +   +
Sbjct: 1240 DKEEYDR---KEKELREKIENLSKEIYELNRQNDEQTNEFANKIITLESLNTDLND-QME 1295

Query: 1252 KTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTS-----LQNKLQDKEEHL 1306
            +   E   Q+   + KY+QL    +   +E  +++   +Q+          KL++  E  
Sbjct: 1296 QIRSEKDKQIQLVKEKYQQLESEYRGQIEELQSQLKWEKQINEDSDLHSNKKLEENYEFN 1355

Query: 1307 RNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQS 1366
             N  E      N       +   E  ++                DL+T +Q+   + E+ 
Sbjct: 1356 ENSAEGQVRSGNLGSQNNQDSRQELDSYKERVNILEVQIIKLKNDLQT-SQNTNTVIERQ 1414

Query: 1367 ILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTIT 1426
            I  ++  N    K              ++++ + K + L  + E +   I  +     + 
Sbjct: 1415 IKGLHSTNENFAKE-------IDSLLIKLDNEQKKYIALQKETEEQIESITDEKRHLKMN 1467

Query: 1427 ---LTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRL-KMHENANHYETMQKESEI 1482
               L ++ +E EN  ++L + +K I+ L  + E     L L ++        ++Q +++ 
Sbjct: 1468 FDELLEKMNESENF-ERLNQLQKEIDSLKIQNEQLQKQLSLPQVGSQIERQSSIQIQNQG 1526

Query: 1483 ERVKLIEELNVKITESVSLNKQVAELN 1509
            + V+  E+ NV      S ++++ E+N
Sbjct: 1527 QVVQKSEQ-NVDKPAKKSGSEEIHEIN 1552



 Score = 94.7 bits (225), Expect = 2e-17
 Identities = 198/974 (20%), Positives = 402/974 (41%), Gaps = 97/974 (9%)

Query: 90   ISESLANTLKQKEILMEKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSN 149
            I++ L    KQ +    K+   K  + +S +TI +               QL D  H   
Sbjct: 630  INQQLQKLSKQSQEQAAKVFGIKHQNMQSISTINQQLAEQIHSRQ-----QLIDTLH--Q 682

Query: 150  TIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAK-------NKATTXXXXXXXX 202
             I +K+ A+  LQ K   ++    + +E+I E   I+E K       NK  +        
Sbjct: 683  EITQKNRAIHELQAKNTNLQNISYEKEERITELQNILEEKELEINDLNKKESLLNEDIMR 742

Query: 203  XXXXXXXXXED--TKQQ--------MTKMQ---ENFIAMEAEWKDEKQRLLKDIESKDVR 249
                     ++   K+Q        +T++Q   EN+  +E    +E   L   +E  + R
Sbjct: 743  LKDTLVAIQDELIAKKQEISHHINDLTQLQEKNENYEQIEQNMNEELVNL--QLEYNNYR 800

Query: 250  ISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTE 309
                E+  KL    + EI+L+  +L ++L+Q              L ++  +     +T 
Sbjct: 801  EEVEEKIEKLTLEIK-EINLQKDELQEQLDQIQTQKQSLSEERDVLIQEKEDLIQNNQTL 859

Query: 310  IEEKGSLEI---ANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKG 366
            I+EK +L++   +  T + ++ +  +       +   ++  K  + G +    S    K 
Sbjct: 860  IQEKENLQVEIESLQTSMEQQKDAFDKEIDAFEEIVLQIIEK-GSSGDQDHHASLQQPKL 918

Query: 367  SPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEY 426
            + LI   + +    + +    +   + LNQD +     NE   +E + Q  +    +K  
Sbjct: 919  TSLIEILNKKMVEVQSQKEHLEQEMKYLNQDIE-----NEKMTVEQLYQECDNLAEEKNI 973

Query: 427  VISEKDTXXXXXXXXXXGKDTLIAQLQ--LEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQ 484
            +    D             +    QL+   E +Q+ E           E   +I +++ +
Sbjct: 974  MAQNYDNALAEKKQVCELLEEKTQQLRELQEKEQNKENDFQHFENQIKEKEAQILELENK 1033

Query: 485  LKQELNDEIKDVN--VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQK 542
            L QE+N   ++VN  +K+ I+ L   EE I  L + +D  N     +K N   K+ ++Q+
Sbjct: 1034 L-QEINKTTEEVNSELKEKIDVLHEKEETIKILKESLDNYN-----IKYN--TKVSELQE 1085

Query: 543  TIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKM 602
              D  S++ +  K+     EE + L+Q+++   +E      +L+  +     + D+  K 
Sbjct: 1086 IHDYISQMQNDIKQKEAQIEESNQLNQQLSNQYQELQIQNENLIYQNQNNFNQVDLLSKQ 1145

Query: 603  IEMEN------------LAETRLKAISLLESQKF---DLVQELHILQQKYDEVEDKLAD- 646
            I+ +N            L+ T      L+ S K    +L Q          E E ++A+ 
Sbjct: 1146 IQEQNQLIEDLNLEKNTLSTTLFSNQELINSYKLKLEELQQAFEFNNTTISEYEKQIAEL 1205

Query: 647  ---ISQLQ--SDQVCSEIKSVHL-EEQI--------DALSASKKELALVIENLKLDKEQL 692
               +SQL     Q  SE+++  L EE+I        +     +KEL   IENL    +++
Sbjct: 1206 NSTVSQLNLLCQQKDSELQNYKLYEEKISNHQLIDKEEYDRKEKELREKIENL---SKEI 1262

Query: 693  YGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQF- 751
            Y   +  +    +  NK+      N DL D++E++ +EK  ++  ++  E+  ++++++ 
Sbjct: 1263 YELNRQNDEQTNEFANKIITLESLNTDLNDQMEQIRSEKDKQI--QLVKEKYQQLESEYR 1320

Query: 752  GIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQK 811
            G   ++Q +  + + I  +   + ++  +LEE+    E+      R  +      Q+ ++
Sbjct: 1321 GQIEELQSQLKWEKQINEDSDLHSNK--KLEENYEFNENSAEGQVRSGNLGSQNNQDSRQ 1378

Query: 812  AYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSD 871
                Y  + + L  ++  L +  +  +     IE + K L   N+   +E  +L I L +
Sbjct: 1379 ELDSYKERVNILEVQIIKLKNDLQTSQNTNTVIERQIKGLHSTNENFAKEIDSLLIKLDN 1438

Query: 872  MQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIE 931
             Q+ Y AL +K     +      K   ++   E   K    E+   + Q +KEI+ L+I+
Sbjct: 1439 EQKKYIAL-QKETEEQIESITDEKRHLKMNFDELLEKMNESENFERLNQLQKEIDSLKIQ 1497

Query: 932  FNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQ-LQEYKNNIEN--LNMNVEELNKMNLEL 988
             N Q++  +   +V   + E+      Q + Q +Q+ + N++        EE++++N  L
Sbjct: 1498 -NEQLQKQLSLPQV-GSQIERQSSIQIQNQGQVVQKSEQNVDKPAKKSGSEEIHEIN--L 1553

Query: 989  IDKHVQKQQTQSPD 1002
            ++  ++   +Q PD
Sbjct: 1554 VNDILRSPISQKPD 1567



 Score = 91.9 bits (218), Expect = 1e-16
 Identities = 218/1060 (20%), Positives = 429/1060 (40%), Gaps = 99/1060 (9%)

Query: 590  SGRMIESDVYKKMIE--MENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADI 647
            SG++   + YK++ +     + E  LK I+ +  +   LV++  I +Q Y ++E+     
Sbjct: 51   SGQINYLNEYKQIFKNYRNTIQEGTLKNINAISDKVCKLVEDT-IQKQVYSKIENNWRVK 109

Query: 648  SQLQSDQVCSEIKSV--HLEEQIDALSASKKELAL--VIENLKLDKEQLYGTIKDLENDK 703
             Q Q ++   EI S   +   QID L+          +I    L   QL  +   L N  
Sbjct: 110  IQQQHEKCFQEIVSSLQNTFSQIDELAKQNNHYTSLNIISIRSLYDNQLSQSKLQLRNIN 169

Query: 704  EDIMNKLQNYIQEN----MDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQE 759
            ED + +LQN I ++    + L  K E++ A   SE  AK  +E Q K         K QE
Sbjct: 170  EDNLIRLQNQIDDHFKKYVSLYQKAEQIQALADSES-AKYKNEAQQK--------NKQQE 220

Query: 760  RDLYIENIESELSKYKSRICRLEESIAV----MEDRRYSLERKADQLGSYLQEKQKAYSE 815
            +       E++ S  +  I   ++   V      +++ S    A      L + +  + +
Sbjct: 221  KQG-----ENQTSSTQGAISTNDDDDDVGFSKKTEKKESKNNDAANQSGLLSKIKNIFKK 275

Query: 816  YTIQEDELVNRLAVLMDHDRV-VEKQ-LLEIEHENKELQKKNQILLEENQNLQISLSDMQ 873
               +  + VN   V  D     ++KQ + E + EN  L +   I+           SD  
Sbjct: 276  EDSRASQ-VNLEGVSNDFRYCPIKKQWIFEGQEENSVLDEPPPIIPVNQGAANAQQSDQN 334

Query: 874  QHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKE--------- 924
                A    +N    A++ S  Y  +         R   + +    +K+K+         
Sbjct: 335  NSVAADNSVSNLGSGAQTPSQAYDPKQALTRPVNYRNARDLKAKAKEKEKQKPRPAAFNF 394

Query: 925  IEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQL--EAQLQEYKNNIENLNMNVEE-L 981
            ++  ++E N     +  +     E+  +NIE   QL  +A L    NN E   +N+ E L
Sbjct: 395  MQQQKVEENMSNYDSTANNFDSTEQNIQNIESNNQLSSDANLGLQFNNQEVSQVNISEIL 454

Query: 982  NKMN--LELIDKHVQKQ---QTQSPDYTE--QYINEINKLNA--LLKQKDEEIIALNQKI 1032
              +N  ++ I K +  Q   +T+  D+ E    I E   LNA  + KQ  EEI   N K+
Sbjct: 455  ESLNSQIQFIIKSLPDQIAKETEFIDFEEIESRIQEQASLNAEKIFKQLKEEIFKQN-KL 513

Query: 1033 NNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVRE----Q 1088
            N   +  M   + YE ++ Q T    ++ ++     + L++ +  N  +   V E    Q
Sbjct: 514  NTKIIRRMQ--NSYEEQIRQLTHDYMDLMDQSIAQERHLIEDETLNSTIDSSVIEFCSKQ 571

Query: 1089 DDQIKELKETKLTFEMNIPKTEGM---IISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQ 1145
             ++IK+L+   +  +  + K +     +I + ++ ++   N +              K+ 
Sbjct: 572  SEKIKQLQTELMKKQCMMGKQDNKNMEVIKNMVDKINQLENKLLKYTDMELENENLQKIN 631

Query: 1146 EEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQ 1205
            ++ + + ++S  QEQ+AK+       +  +  + T+N +L       Q+ I+ L  ++ Q
Sbjct: 632  QQLQKLSKQS--QEQAAKV---FGIKHQNMQSISTINQQLAEQIHSRQQLIDTLHQEITQ 686

Query: 1206 LNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFE 1265
             N     L +    L++ IS   ++R  E+  + ++   +   D  K E  L   +   +
Sbjct: 687  KNRAIHELQAKNTNLQN-ISYEKEERITELQNILEEKELEIN-DLNKKESLLNEDIMRLK 744

Query: 1266 SKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRS 1325
                 + D + +  QE ++ I     +T LQ K ++ E+  +N+ E+  ++  +    R 
Sbjct: 745  DTLVAIQDELIAKKQEISHHI---NDLTQLQEKNENYEQIEQNMNEELVNLQLEYNNYRE 801

Query: 1326 EIED--EKVAFXXXXXXXXXXXXXXXXD-LRTENQSYKQ------MQEQSILNINEENAQ 1376
            E+E+  EK+                  D ++T+ QS  +       +++ ++  N+   Q
Sbjct: 802  EVEEKIEKLTLEIKEINLQKDELQEQLDQIQTQKQSLSEERDVLIQEKEDLIQNNQTLIQ 861

Query: 1377 LKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSE---IYQKTHEYTITLTQRNDE 1433
             K++             +  DA  K ++   ++ L+  E      + H  ++   +    
Sbjct: 862  EKENLQVEIESLQTSMEQQKDAFDKEIDAFEEIVLQIIEKGSSGDQDHHASLQQPKLTSL 921

Query: 1434 FENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNV 1493
             E + +++VE + + E L    E E+  L   +       E + +E +     L EE N+
Sbjct: 922  IEILNKKMVEVQSQKEHL----EQEMKYLNQDIENEKMTVEQLYQECD----NLAEEKNI 973

Query: 1494 ---KITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRAS 1550
                   +++  KQV EL   LEE+  +  E+Q   +N+E +     ++I   +  +   
Sbjct: 974  MAQNYDNALAEKKQVCEL---LEEKTQQLRELQEKEQNKENDFQHFENQIKEKEAQILEL 1030

Query: 1551 SSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELD 1590
             +K+Q+      +      E++D    KE    + +  LD
Sbjct: 1031 ENKLQEINKTTEEVNSELKEKIDVLHEKEETIKILKESLD 1070


>UniRef50_A2F8N3 Cluster: Viral A-type inclusion protein, putative;
            n=1; Trichomonas vaginalis G3|Rep: Viral A-type inclusion
            protein, putative - Trichomonas vaginalis G3
          Length = 1513

 Score =  157 bits (381), Expect = 2e-36
 Identities = 234/1095 (21%), Positives = 484/1095 (44%), Gaps = 63/1095 (5%)

Query: 472  TEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQI-TQLNDEIDAANKNMIKVK 530
            TE+   I+ +Q++   +L  +      KD  E    + E +    +++I A    + K+K
Sbjct: 324  TEETMLISPMQDKNNSDLM-QFTPQKSKDENEIFFLSPEPLKNDSSEKIHALESEIQKLK 382

Query: 531  SNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGN---LQLHLVD 587
             ++K   + +       S + +    I +L  E+    QK+ EL   K N   LQ   V 
Sbjct: 383  QDNKSLEEALSLVNSTKSDIKELENVIEQLQGEIAEKDQKIKELSSSKENDEILQELEVQ 442

Query: 588  YDSGRMIESDVYKKM--IEMENLAETRLK-AISLLESQKFDLVQELHILQQKYDEVEDKL 644
                  I   + KK   IEM+      L+  I  L+++   L +E   L +  +   D  
Sbjct: 443  IQEKENISKSLQKKAEEIEMKEKENKELEQVIDSLKTEIDSLTKENEKLNKACERASDAA 502

Query: 645  ADISQLQSDQVCSEI-KSVH-LEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLEND 702
             ++S+ + D +  E+ K ++  EE+I    +  KEL   I++++ DK+          N 
Sbjct: 503  TNLSK-ERDMIVDEMNKDINEKEEEIQNNLSKIKELEQKIKDIETDKDLTQN------NK 555

Query: 703  KEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGID-----AKI 757
             E+I+N+LQN IQ N+    KLE+   E + E  A++++ +  +I  +   +     +KI
Sbjct: 556  SEEIINELQNKIQNNLSKIRKLEQKIKE-LEEANAQLSNNKSEEIINELQNEIQNNLSKI 614

Query: 758  QERDLYIENIES-ELSKYKS--RICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYS 814
            +E +  I+ +ES +LS  KS   I +LE  IA  ++    + ++ + L   ++E +K  +
Sbjct: 615  RELEQKIKELESTQLSNNKSDETINQLEVEIAKNKETIEKINKENNYLHKKVEETEKQIN 674

Query: 815  EYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKE-LQKKNQILLEENQNLQISLSDMQ 873
                 +++L N +  L      +E ++ E  +E+K+ ++K  + + E     +  LS+++
Sbjct: 675  LLETDKNKLQNMVNELETSKSDLEAKISENSNEDKQQIEKLEESIKEIKSESERQLSELR 734

Query: 874  QHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEH-QTLIVQKKKEIEDLEIEF 932
               N +  + N+  +A S S + +T +++LE  L     E  +    +  ++I+ +  +F
Sbjct: 735  NKLNEVEFEKNQ--IASSLSVEKET-VKNLEEQLSTAQSEELENANKELNEKIKQISDDF 791

Query: 933  NTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKH 992
            + +     ++K  L +  EK  +  ++L ++L   +++IE +     EL     E  +  
Sbjct: 792  SNKSSEFEKEKSDLQKILEKFKKENSELHSKLDFSEDSIEKIKSQ-SELKLTQSEKDNSE 850

Query: 993  VQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIA-LNQKINNAQVSYMSMVSDYESKLA 1051
            ++K+ +Q        ++++N   + L++K EEI A L+QK          M+      L 
Sbjct: 851  LRKKLSQLQREMNDSLSKLNSEKSDLERKLEEISADLSQK--------EGMLKKAMDSLK 902

Query: 1052 QFTTKLENMEEEMQRVSKQL-LDSK--QHNEELQILVREQDDQIKELKETKLTFEMN--I 1106
            +  +KL+ +EEE   +  Q+ +DS+  + + + +I    +D +IK  K  K   E N  +
Sbjct: 903  KMKSKLDKLEEEKSSLENQMKVDSEKAETDRKSEIAKINEDFEIKFDKLKKQLEEANNSL 962

Query: 1107 PKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNT 1166
             K E  +  +    + +D                 +  +E     +E+++L +++  L  
Sbjct: 963  EKKENELEEAKKALLRNDTEQ--KAEFAKLSKMSEIAHEENARIAKEKALLTKENESLKK 1020

Query: 1167 ELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISS 1226
            E ++       L    +EL         +I+ LK + + + T+ +N L    E+   +  
Sbjct: 1021 ENEKQKEDYSNLREKYSELEKEVKDLASEIDTLKKEKQNIETKLENELKKSNEMSQMLQI 1080

Query: 1227 AVDQRGFEIAELWKQHLAQREA--DFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETN 1284
            A  Q+  + A + +Q  A +E+    +K   EL   +SA   +  +L ++++++ ++   
Sbjct: 1081 ADSQKE-QSANMQRQIDALKESLNSTEKQNSELISSVSALSEENSKLKNTIEAAKKKVNA 1139

Query: 1285 KIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVI-NQIEILRSEIEDEKVAFXXXXXXXXX 1343
            +I       S   +LQ+  E+L + +   A+   + I+ L++EI   K+           
Sbjct: 1140 EIKKNSDFQSKIEELQNSIENLNSEKISQAEKAESSIKSLQNEISSLKLKISEDDEKLSS 1199

Query: 1344 XXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVL 1403
                       + +  K + E+ I  + E +++ +K S            +  +A  K  
Sbjct: 1200 FESSLSQVTAEKEEIQKSLNEE-IAKMAEISSEKEKISVQLQNIQKENEQKSQEA-IKSS 1257

Query: 1404 ELTHQLELKDSEIYQKTHEYTITLTQRND--EFENVRQQLVEYEKRIEDLTYEKES-ELA 1460
            ELT ++E  +S + ++  E        ND    E+ +    E EK  +++   KE+ E+A
Sbjct: 1258 ELTKRIEELESSLRKEIMENNNLRQVHNDVSNAEDNKHLQDENEKLRKEIEESKENFEIA 1317

Query: 1461 ILRL------KMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEE 1514
              +       K+ +N        K S  ++V+ +EE N  + +S+S +++V     A   
Sbjct: 1318 KKQFIEEESAKIEQNIKRKFEASKNSLSKKVESLEEENRNLQKSISDSEKVTRNLSAKVS 1377

Query: 1515 EVAKTNEMQTALENQ 1529
            E  + N   + L+ Q
Sbjct: 1378 EFDQINRQNSELKQQ 1392



 Score =  155 bits (375), Expect = 1e-35
 Identities = 249/1164 (21%), Positives = 521/1164 (44%), Gaps = 132/1164 (11%)

Query: 214  TKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSK 273
            T Q+     E F       K++    +  +ES+   I  L++ NK LE A   ++   S 
Sbjct: 345  TPQKSKDENEIFFLSPEPLKNDSSEKIHALESE---IQKLKQDNKSLEEALSLVNSTKSD 401

Query: 274  LAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIEL-LE 332
            + +ELE                 K+    S +E  EI ++  ++I     ++K ++   E
Sbjct: 402  I-KELENVIEQLQGEIAEKDQKIKEL--SSSKENDEILQELEVQIQEKENISKSLQKKAE 458

Query: 333  HLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSE 392
             +  + ++ NKELE  + ++ TE  +++  ++K +    R S  + A+ +      +  E
Sbjct: 459  EIEMKEKE-NKELEQVIDSLKTEIDSLTKENEKLNKACERAS--DAATNLSKERDMIVDE 515

Query: 393  TLNQDTDKKINK--NEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKD-TLI 449
             +N+D ++K  +  N ++K++ + Q +     DK+   + K              + + I
Sbjct: 516  -MNKDINEKEEEIQNNLSKIKELEQKIKDIETDKDLTQNNKSEEIINELQNKIQNNLSKI 574

Query: 450  AQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAE 509
             +L+ + ++  E  + +    + E +NE+   Q +++  L+       +++L +K+K  E
Sbjct: 575  RKLEQKIKELEEANAQLSNNKSEEIINEL---QNEIQNNLS------KIRELEQKIKELE 625

Query: 510  EQITQLNDEIDAANKNMIKVK-SNHKLKLKQMQKTIDNF--SKVSDSNKEIVRLTEELHH 566
               TQL++       N ++V+ + +K  ++++ K  +N+   KV ++ K+I  L  + + 
Sbjct: 626  S--TQLSNNKSDETINQLEVEIAKNKETIEKINKE-NNYLHKKVEETEKQINLLETDKNK 682

Query: 567  LSQKVAELEEEKGNLQLHLV-----DYDSGRMIESDVYKKMIEMEN-LAETRLKAISLLE 620
            L   V ELE  K +L+  +      D      +E  + +   E E  L+E R K ++ +E
Sbjct: 683  LQNMVNELETSKSDLEAKISENSNEDKQQIEKLEESIKEIKSESERQLSELRNK-LNEVE 741

Query: 621  SQKFDLVQELHILQQKYDEVEDKL--ADISQLQS--DQVCSEIKSVH--LEEQIDALSAS 674
             +K  +   L + ++    +E++L  A   +L++   ++  +IK +      +       
Sbjct: 742  FEKNQIASSLSVEKETVKNLEEQLSTAQSEELENANKELNEKIKQISDDFSNKSSEFEKE 801

Query: 675  KKELALVIENLKLDKEQLYGTIKDLENDKEDIMN----KLQNYIQENMDLTDKLEKMSAE 730
            K +L  ++E  K +  +L+  +   E+  E I +    KL    ++N +L  KL ++  E
Sbjct: 802  KSDLQKILEKFKKENSELHSKLDFSEDSIEKIKSQSELKLTQSEKDNSELRKKLSQLQRE 861

Query: 731  KISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVME- 789
             +++ L+K+N E+    +    I A + +++  ++     L K KS++ +LEE  + +E 
Sbjct: 862  -MNDSLSKLNSEKSDLERKLEEISADLSQKEGMLKKAMDSLKKMKSKLDKLEEEKSSLEN 920

Query: 790  -----------DRRYSL-------ERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLM 831
                       DR+  +       E K D+L   L+E   +  +   +E+EL      L+
Sbjct: 921  QMKVDSEKAETDRKSEIAKINEDFEIKFDKLKKQLEEANNSLEK---KENELEEAKKALL 977

Query: 832  DHDRVVEKQ------LLEIEHE-NKELQKKNQILLEENQNLQISLSDMQQHYNALVEKAN 884
             +D   + +      + EI HE N  + K+  +L +EN++L+      ++ Y+ L EK +
Sbjct: 978  RNDTEQKAEFAKLSKMSEIAHEENARIAKEKALLTKENESLKKENEKQKEDYSNLREKYS 1037

Query: 885  RT-----DLA-ESESTKYQTQLRD--LESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQI 936
                   DLA E ++ K + Q  +  LE+ LK+     Q L +   ++ +   ++   QI
Sbjct: 1038 ELEKEVKDLASEIDTLKKEKQNIETKLENELKKSNEMSQMLQIADSQKEQSANMQ--RQI 1095

Query: 937  ESAIRDKKVLNEKYEKNIEYVTQLEAQLQE---YKNNIENLNMNVEELNKMNLELIDKHV 993
            ++    K+ LN   ++N E ++ + A  +E    KN IE     V    K N +   K +
Sbjct: 1096 DAL---KESLNSTEKQNSELISSVSALSEENSKLKNTIEAAKKKVNAEIKKNSDFQSK-I 1151

Query: 994  QKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQF 1053
            ++ Q    +   + I++  K  + +K    EI +L  KI+         +S +ES L+Q 
Sbjct: 1152 EELQNSIENLNSEKISQAEKAESSIKSLQNEISSLKLKISEDD----EKLSSFESSLSQV 1207

Query: 1054 TTKLENME----EEMQRVSKQLLDSKQHNEELQILVREQDDQIKE-LKETKLTFEMNIPK 1108
            T + E ++    EE+ ++++   + ++ + +LQ + +E + + +E +K ++LT    I +
Sbjct: 1208 TAEKEEIQKSLNEEIAKMAEISSEKEKISVQLQNIQKENEQKSQEAIKSSELT--KRIEE 1265

Query: 1109 TEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTEL 1168
             E  +    +E      NN+               +Q+E E +++    + + +K N E+
Sbjct: 1266 LESSLRKEIMEN-----NNLRQVHNDVSNAEDNKHLQDENEKLRK----EIEESKENFEI 1316

Query: 1169 QECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAV 1228
             +   + I+ E+   E          + N L  K+E L  EN NL  ++++    ++  +
Sbjct: 1317 AK--KQFIEEESAKIEQNIKRKFEASK-NSLSKKVESLEEENRNLQKSISD-SEKVTRNL 1372

Query: 1229 DQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVT 1288
              +  E  ++ +Q+             EL+ QLS F  ++  L+ + +  TQEE   + +
Sbjct: 1373 SAKVSEFDQINRQN------------SELKQQLSHFTKRHNDLI-AEREITQEEC--LRS 1417

Query: 1289 MEQVTSLQNKLQDKEEHLRNLQEK 1312
              Q   L  K+ + E  L  LQ +
Sbjct: 1418 QHQAEILTKKVSELEAKLEKLQSE 1441



 Score =  151 bits (365), Expect = 2e-34
 Identities = 239/1097 (21%), Positives = 476/1097 (43%), Gaps = 94/1097 (8%)

Query: 449  IAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSA 508
            I +L+ +++   E  SL++  +   D+ E+  V EQL+ E+ +  KD  +K+L    K  
Sbjct: 378  IQKLKQDNKSLEEALSLVN--STKSDIKELENVIEQLQGEIAE--KDQKIKELSSS-KEN 432

Query: 509  EEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNK-EIVRLTEELHHL 567
            +E + +L  +I    +N+ K       +++  +K      +V DS K EI  LT+E   L
Sbjct: 433  DEILQELEVQIQE-KENISKSLQKKAEEIEMKEKENKELEQVIDSLKTEIDSLTKENEKL 491

Query: 568  SQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLV 627
            ++      +   NL     + D   MI  ++ K + E E   +  L  I  LE +  D+ 
Sbjct: 492  NKACERASDAATNLSK---ERD---MIVDEMNKDINEKEEEIQNNLSKIKELEQKIKDIE 545

Query: 628  QELHILQQ-KYDEVEDKLADISQLQSDQVCS-EIKSVHLEEQIDALSASKKE-----LAL 680
             +  + Q  K +E+ ++L +  Q    ++   E K   LEE    LS +K E     L  
Sbjct: 546  TDKDLTQNNKSEEIINELQNKIQNNLSKIRKLEQKIKELEEANAQLSNNKSEEIINELQN 605

Query: 681  VIENLKLDKEQLYGTIKDLE------NDKEDIMNKLQNYIQENMDLTDKLEKMSA---EK 731
             I+N      +L   IK+LE      N  ++ +N+L+  I +N +  +K+ K +    +K
Sbjct: 606  EIQNNLSKIRELEQKIKELESTQLSNNKSDETINQLEVEIAKNKETIEKINKENNYLHKK 665

Query: 732  ISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDR 791
            + E   +IN  E  K + Q  ++     +      I    ++ K +I +LEESI  ++  
Sbjct: 666  VEETEKQINLLETDKNKLQNMVNELETSKSDLEAKISENSNEDKQQIEKLEESIKEIKSE 725

Query: 792  RYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKEL 851
                ER+  +L + L E +  + +  I     V +  V    +++   Q  E+E+ NKEL
Sbjct: 726  S---ERQLSELRNKLNEVE--FEKNQIASSLSVEKETVKNLEEQLSTAQSEELENANKEL 780

Query: 852  QKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRIT 911
             +K + + ++  N        +     ++EK  +      E+++  ++L   E ++++I 
Sbjct: 781  NEKIKQISDDFSNKSSEFEKEKSDLQKILEKFKK------ENSELHSKLDFSEDSIEKIK 834

Query: 912  HEHQTLIVQKKKE-------IEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQL 964
             + +  + Q +K+       +  L+ E N  +     +K  L  K E+    ++Q E  L
Sbjct: 835  SQSELKLTQSEKDNSELRKKLSQLQREMNDSLSKLNSEKSDLERKLEEISADLSQKEGML 894

Query: 965  QEYKNNIENLNMNVEELNKMNLELIDK-HVQKQQTQSPDYTE-QYINEIN--KLNALLKQ 1020
            ++  ++++ +   +++L +    L ++  V  ++ ++   +E   INE    K + L KQ
Sbjct: 895  KKAMDSLKKMKSKLDKLEEEKSSLENQMKVDSEKAETDRKSEIAKINEDFEIKFDKLKKQ 954

Query: 1021 KDEEIIALNQKINNAQVSYMSMV-SDYESK--LAQFTTKLENMEEEMQRVSKQLLDSKQH 1077
             +E   +L +K N  + +  +++ +D E K   A+ +   E   EE  R++K+     + 
Sbjct: 955  LEEANNSLEKKENELEEAKKALLRNDTEQKAEFAKLSKMSEIAHEENARIAKEKALLTKE 1014

Query: 1078 NEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXX 1137
            NE L+    +Q +    L+E     E  +       ++S I+ +  +  N++        
Sbjct: 1015 NESLKKENEKQKEDYSNLREKYSELEKEVKD-----LASEIDTLKKEKQNIETKLENELK 1069

Query: 1138 XXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQIN 1197
                 K  E  + +Q     +EQSA +  ++      +   E  N+EL        E+ +
Sbjct: 1070 -----KSNEMSQMLQIADSQKEQSANMQRQIDALKESLNSTEKQNSELISSVSALSEENS 1124

Query: 1198 QLKSKLE----QLNTE---NDNLLSTVAELRSSISSAVDQR--GFEIAELWKQHLAQREA 1248
            +LK+ +E    ++N E   N +  S + EL++SI +   ++    E AE   + L    +
Sbjct: 1125 KLKNTIEAAKKKVNAEIKKNSDFQSKIEELQNSIENLNSEKISQAEKAESSIKSLQNEIS 1184

Query: 1249 DFQKTEHELRVQLSAFESKYEQLL---DSVQSSTQEETNKIVTM----EQVTSLQNKLQD 1301
              +    E   +LS+FES   Q+    + +Q S  EE  K+  +    E+++     +Q 
Sbjct: 1185 SLKLKISEDDEKLSSFESSLSQVTAEKEEIQKSLNEEIAKMAEISSEKEKISVQLQNIQK 1244

Query: 1302 KEEHLRNLQEKYADVINQIEILRSEIEDEKVA-FXXXXXXXXXXXXXXXXDLRTENQSYK 1360
            + E       K +++  +IE L S +  E +                    L+ EN+  +
Sbjct: 1245 ENEQKSQEAIKSSELTKRIEELESSLRKEIMENNNLRQVHNDVSNAEDNKHLQDENEKLR 1304

Query: 1361 QMQEQSILN--------INEENAQLKKS-SXXXXXXXXXXXXRVNDAEAKVLELTHQLEL 1411
            +  E+S  N        I EE+A+++++              +V   E +   L  Q  +
Sbjct: 1305 KEIEESKENFEIAKKQFIEEESAKIEQNIKRKFEASKNSLSKKVESLEEENRNL--QKSI 1362

Query: 1412 KDSEIYQKTHEYTIT-LTQRNDEFENVRQQLVEYEKRIEDLTYEKE-SELAILRLKMHEN 1469
             DSE   +     ++   Q N +   ++QQL  + KR  DL  E+E ++   LR +    
Sbjct: 1363 SDSEKVTRNLSAKVSEFDQINRQNSELKQQLSHFTKRHNDLIAEREITQEECLRSQHQAE 1422

Query: 1470 ANHYETMQKESEIERVK 1486
                +  + E+++E+++
Sbjct: 1423 ILTKKVSELEAKLEKLQ 1439



 Score =  125 bits (301), Expect = 1e-26
 Identities = 208/1091 (19%), Positives = 479/1091 (43%), Gaps = 93/1091 (8%)

Query: 144  VTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXX 203
            +  LS++ KE D  L  L+V+++  E     LQ+K  E    IE K K            
Sbjct: 423  IKELSSS-KENDEILQELEVQIQEKENISKSLQKKAEE----IEMKEKENKELEQVIDSL 477

Query: 204  XXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQR-LLKDIESKDVRISSLEEANKLLEA 262
                    ++  +++ K  E   A +A     K+R ++ D  +KD+     E  N L + 
Sbjct: 478  KTEIDSLTKE-NEKLNKACER--ASDAATNLSKERDMIVDEMNKDINEKEEEIQNNLSKI 534

Query: 263  ARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQ-SIEPSCEEKTEIEEKGSLEIANM 321
               E  ++  +  ++L Q              +    S     E+K +  E+ + +++N 
Sbjct: 535  KELEQKIKDIETDKDLTQNNKSEEIINELQNKIQNNLSKIRKLEQKIKELEEANAQLSN- 593

Query: 322  TELTKKIELLEHLNCQIRQT---NKELENKLATMGTESKAVSSPSKKGSPL-ISRKSGRN 377
                K  E++  L  +I+      +ELE K+  + +   + +   +  + L +     + 
Sbjct: 594  ---NKSEEIINELQNEIQNNLSKIRELEQKIKELESTQLSNNKSDETINQLEVEIAKNKE 650

Query: 378  TASKMKSPWSQLSSETLNQDTDKKIN--KNEIAKLEMVIQSLNKDLVDKEYVISEKDTXX 435
            T  K+    + L  +   ++T+K+IN  + +  KL+ ++  L     D E  ISE     
Sbjct: 651  TIEKINKENNYLHKKV--EETEKQINLLETDKNKLQNMVNELETSKSDLEAKISENSNED 708

Query: 436  XXXXXXXXGKDTLIAQLQLEHQQHME--GPSLIHVGTNTEDVNEIAKVQEQLKQELNDEI 493
                      +  I +++ E ++ +      L  V      +     V+++  + L +++
Sbjct: 709  KQQIEKL---EESIKEIKSESERQLSELRNKLNEVEFEKNQIASSLSVEKETVKNLEEQL 765

Query: 494  KDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDS 553
                 ++L    K   E+I Q++D+    +    K KS+ +  L++ +K         D 
Sbjct: 766  STAQSEELENANKELNEKIKQISDDFSNKSSEFEKEKSDLQKILEKFKKENSELHSKLDF 825

Query: 554  NKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRL 613
            +++ +   +    L  K+ + E++   L+  L      R +   + K   E  +L E +L
Sbjct: 826  SEDSIEKIKSQSEL--KLTQSEKDNSELRKKLSQLQ--REMNDSLSKLNSEKSDL-ERKL 880

Query: 614  KAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSA 673
            + IS       DL Q+  +L++  D ++   + + +L+ ++  S +++    +   A + 
Sbjct: 881  EEISA------DLSQKEGMLKKAMDSLKKMKSKLDKLEEEK--SSLENQMKVDSEKAETD 932

Query: 674  SKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKIS 733
             K E+A + E+ ++  ++L   +++  N  E   N+L+   ++ +   D  +K    K+S
Sbjct: 933  RKSEIAKINEDFEIKFDKLKKQLEEANNSLEKKENELEE-AKKALLRNDTEQKAEFAKLS 991

Query: 734  ELLAKINHEEQSKIQTQFGIDAKIQERDLYIEN--IESELSKYKSRICRLEESIAVMEDR 791
            + +++I HEE ++I  +  +  K +   L  EN   + + S  + +   LE+ +  +   
Sbjct: 992  K-MSEIAHEENARIAKEKALLTK-ENESLKKENEKQKEDYSNLREKYSELEKEVKDLASE 1049

Query: 792  RYSLERKADQLGSYLQEKQKAYSEYT--IQ-EDELVNRLAVLMDHDRVVEKQLLEIEHEN 848
              +L+++   + + L+ + K  +E +  +Q  D    + A +      +++ L   E +N
Sbjct: 1050 IDTLKKEKQNIETKLENELKKSNEMSQMLQIADSQKEQSANMQRQIDALKESLNSTEKQN 1109

Query: 849  KELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLK 908
             EL      L EEN  L+ ++   ++  NA ++K          ++ +Q+++ +L+++++
Sbjct: 1110 SELISSVSALSEENSKLKNTIEAAKKKVNAEIKK----------NSDFQSKIEELQNSIE 1159

Query: 909  RITHEHQTLIVQKKKEIEDLEIEFNT-QIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEY 967
             +  E  +   + +  I+ L+ E ++ +++ +  D+K+    +E ++  VT  + ++Q  
Sbjct: 1160 NLNSEKISQAEKAESSIKSLQNEISSLKLKISEDDEKL--SSFESSLSQVTAEKEEIQ-- 1215

Query: 968  KNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIA 1027
                ++LN  + ++ +++ E     VQ Q  Q  +  EQ   E  K + L K+ +E   +
Sbjct: 1216 ----KSLNEEIAKMAEISSEKEKISVQLQNIQKEN--EQKSQEAIKSSELTKRIEELESS 1269

Query: 1028 LNQKI--NNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNE-ELQIL 1084
            L ++I  NN      + VS+ E          +++++E +++ K++ +SK++ E   +  
Sbjct: 1270 LRKEIMENNNLRQVHNDVSNAEDN--------KHLQDENEKLRKEIEESKENFEIAKKQF 1321

Query: 1085 VREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXL-- 1142
            + E+  +I++  + K     N        +S  +E + ++  N+             L  
Sbjct: 1322 IEEESAKIEQNIKRKFEASKN-------SLSKKVESLEEENRNLQKSISDSEKVTRNLSA 1374

Query: 1143 KVQEEEEFIQERSVLQEQSAKLNTELQECYT--KIIQLETLNTELTGHDVVNQEQINQLK 1200
            KV E ++  ++ S L++Q +       +     +I Q E L ++      +  +++++L+
Sbjct: 1375 KVSEFDQINRQNSELKQQLSHFTKRHNDLIAEREITQEECLRSQHQAE--ILTKKVSELE 1432

Query: 1201 SKLEQLNTEND 1211
            +KLE+L +E D
Sbjct: 1433 AKLEKLQSEAD 1443



 Score =  122 bits (294), Expect = 8e-26
 Identities = 220/1169 (18%), Positives = 489/1169 (41%), Gaps = 93/1169 (7%)

Query: 470  TNTEDV--NEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMI 527
            TN ++V   ++A + E L Q+ N +I +   K  I++L    E++ + N+E++       
Sbjct: 60   TNEKEVLQRQLATLNEHL-QKKNSQISEA--KTYIKRLAIENEKLKR-NNEMEELILAFD 115

Query: 528  KVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVD 587
            + +  ++ +++ ++K  D    V +  + I +L +E     Q + + +   G+L   L  
Sbjct: 116  EDRKKYEREIEVLRKRADGDGIVDELLQNITKLEKENEEKDQIIQQYKG--GSLFSGLKS 173

Query: 588  YDSGRMIESDVYKKMIEMENLAETR--LKAISLLESQKFDLVQELHILQQKYDEVEDKLA 645
            +      +    K   E+ NL +    LK     +S + + +Q+    Q++  E + +  
Sbjct: 174  FIQQSSDDDPTAKFKSEIANLKKELYLLKRNKSTDSPQEEELQQPPTPQEQPKEPQREEN 233

Query: 646  DISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDK-----EQLYGTIKDLE 700
                  S    S +K    E+        K  L     NLK +      ++L+       
Sbjct: 234  PKPSENSKGFFSSLKLPKAEDPEKNAHLPKMLLGGNASNLKPESTTRLTDELFPDFSTAG 293

Query: 701  NDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQER 760
               E       +   E  +++ K +  SA     +L     ++ +    QF       E 
Sbjct: 294  KSPEQPKFGDFSTASEKENISPKFDDFSAATEETMLISPMQDKNNSDLMQFTPQKSKDEN 353

Query: 761  DLY--------------IENIESELSKYKSRICRLEESIAVMEDRRYS---LERKADQLG 803
            +++              I  +ESE+ K K     LEE+++++   +     LE   +QL 
Sbjct: 354  EIFFLSPEPLKNDSSEKIHALESEIQKLKQDNKSLEEALSLVNSTKSDIKELENVIEQLQ 413

Query: 804  SYLQEKQKAYSEYTI--QEDELVNRLAVLMDHDRVVEKQL------LEI-EHENKELQK- 853
              + EK +   E +   + DE++  L V +     + K L      +E+ E ENKEL++ 
Sbjct: 414  GEIAEKDQKIKELSSSKENDEILQELEVQIQEKENISKSLQKKAEEIEMKEKENKELEQV 473

Query: 854  ----KNQI--LLEENQNLQISL-------SDMQQHYNALVEKANRT-DLAESESTKYQTQ 899
                K +I  L +EN+ L  +        +++ +  + +V++ N+  +  E E     ++
Sbjct: 474  IDSLKTEIDSLTKENEKLNKACERASDAATNLSKERDMIVDEMNKDINEKEEEIQNNLSK 533

Query: 900  LRDLESNLKRITHEHQTLIVQKKKEI-EDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVT 958
            +++LE  +K I  +       K +EI  +L+ +    +    + ++ + E  E N +   
Sbjct: 534  IKELEQKIKDIETDKDLTQNNKSEEIINELQNKIQNNLSKIRKLEQKIKELEEANAQLSN 593

Query: 959  -QLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNAL 1017
             + E  + E +N I+N    + EL +   EL  +  Q    +S +   Q   EI K    
Sbjct: 594  NKSEEIINELQNEIQNNLSKIRELEQKIKEL--ESTQLSNNKSDETINQLEVEIAKNKET 651

Query: 1018 LKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQ-RVSKQLLDSKQ 1076
            +++ ++E   L++K+   +     + +D ++KL     +LE  + +++ ++S+   + KQ
Sbjct: 652  IEKINKENNYLHKKVEETEKQINLLETD-KNKLQNMVNELETSKSDLEAKISENSNEDKQ 710

Query: 1077 HNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXX 1136
              E+L+  ++E   +  E + ++L  ++N  + E   I+S++    +   N++       
Sbjct: 711  QIEKLEESIKEIKSE-SERQLSELRNKLNEVEFEKNQIASSLSVEKETVKNLEEQLSTAQ 769

Query: 1137 XXXXXLKVQEEEEFIQERSV-LQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQ 1195
                    +E  E I++ S     +S++   E  +    + + +  N+EL      +++ 
Sbjct: 770  SEELENANKELNEKIKQISDDFSNKSSEFEKEKSDLQKILEKFKKENSELHSKLDFSEDS 829

Query: 1196 INQLKS----KLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQ 1251
            I ++KS    KL Q   +N  L   +++L+  ++ ++ +   E ++L ++ L +  AD  
Sbjct: 830  IEKIKSQSELKLTQSEKDNSELRKKLSQLQREMNDSLSKLNSEKSDL-ERKLEEISADLS 888

Query: 1252 KTEHELRVQLSAFESKYEQLLDSVQS--STQEETNKIVTMEQVTSLQNKL----QDKEEH 1305
            + E  L+  + + + K +  LD ++   S+ E   K+ + +  T  ++++    +D E  
Sbjct: 889  QKEGMLKKAMDSLK-KMKSKLDKLEEEKSSLENQMKVDSEKAETDRKSEIAKINEDFEIK 947

Query: 1306 LRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQ 1365
               L+++  +  N +E   +E+E+ K A                      ++   ++ ++
Sbjct: 948  FDKLKKQLEEANNSLEKKENELEEAKKALLRNDTEQKAEFAKLSKMSEIAHEENARIAKE 1007

Query: 1366 SILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTI 1425
              L + +EN  LKK +            + ++ E +V +L  +++       +K  +   
Sbjct: 1008 KAL-LTKENESLKKENEKQKEDYSNLREKYSELEKEVKDLASEIDT-----LKKEKQNIE 1061

Query: 1426 TLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERV 1485
            T  +   +  N   Q+++     ++ +   + ++  L+    E+ N  E    E  I  V
Sbjct: 1062 TKLENELKKSNEMSQMLQIADSQKEQSANMQRQIDALK----ESLNSTEKQNSEL-ISSV 1116

Query: 1486 KLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQN 1545
              + E N K+  ++   K      K +  E+ K ++ Q+ +E  +  I  LN E  +   
Sbjct: 1117 SALSEENSKLKNTIEAAK------KKVNAEIKKNSDFQSKIEELQNSIENLNSEKISQAE 1170

Query: 1546 MVRASSSKIQKHVSFASDTKQGRDEQLDN 1574
               +S   +Q  +S         DE+L +
Sbjct: 1171 KAESSIKSLQNEISSLKLKISEDDEKLSS 1199



 Score =  119 bits (287), Expect = 6e-25
 Identities = 222/1120 (19%), Positives = 483/1120 (43%), Gaps = 103/1120 (9%)

Query: 143  DVTHLSNTIKEKDNALSVL---QVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXX 199
            ++  L    K  + ALS++   +  +K +E  I  LQ +I EKDQ I  K  +++     
Sbjct: 377  EIQKLKQDNKSLEEALSLVNSTKSDIKELENVIEQLQGEIAEKDQKI--KELSSSKENDE 434

Query: 200  XXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKD-IESKDVRISSLEEANK 258
                        E+  + + K  E     E E K+++ + L+  I+S    I SL + N+
Sbjct: 435  ILQELEVQIQEKENISKSLQKKAE-----EIEMKEKENKELEQVIDSLKTEIDSLTKENE 489

Query: 259  LLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEK-GSLE 317
             L  A    S   + L++E +                 ++ I+ +  +  E+E+K   +E
Sbjct: 490  KLNKACERASDAATNLSKERDMIVDEMNKDINEK----EEEIQNNLSKIKELEQKIKDIE 545

Query: 318  I-ANMTELTKKIELLEHLNCQIRQTN---KELENKLATMGTESKAVSSPSKKGSPLISRK 373
               ++T+  K  E++  L  +I+      ++LE K+  +   +  +S+   K   +I+  
Sbjct: 546  TDKDLTQNNKSEEIINELQNKIQNNLSKIRKLEQKIKELEEANAQLSN--NKSEEIINEL 603

Query: 374  SG--RNTASKMKSPWSQL----SSETLNQDTDKKINKNE--IAKLEMVIQSLNKDLVDKE 425
                +N  SK++    ++    S++  N  +D+ IN+ E  IAK +  I+ +NK+     
Sbjct: 604  QNEIQNNLSKIRELEQKIKELESTQLSNNKSDETINQLEVEIAKNKETIEKINKE---NN 660

Query: 426  YVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQL 485
            Y+  + +            K+ L   +        +  + I   +N ED  +I K++E +
Sbjct: 661  YLHKKVEETEKQINLLETDKNKLQNMVNELETSKSDLEAKISENSN-EDKQQIEKLEESI 719

Query: 486  KQ----------ELNDEIKDVNVK--DLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNH 533
            K+          EL +++ +V  +   +   L   +E +  L +++  A    ++  +N 
Sbjct: 720  KEIKSESERQLSELRNKLNEVEFEKNQIASSLSVEKETVKNLEEQLSTAQSEELE-NANK 778

Query: 534  KL--KLKQMQKTIDNFS-----KVSDSNKEIVRLTEELHHLSQKVA----ELEEEKGNLQ 582
            +L  K+KQ+     N S     + SD  K + +  +E   L  K+      +E+ K   +
Sbjct: 779  ELNEKIKQISDDFSNKSSEFEKEKSDLQKILEKFKKENSELHSKLDFSEDSIEKIKSQSE 838

Query: 583  LHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHI----LQQKYD 638
            L L   +      S++ KK+ +++      L   S L S+K DL ++L      L QK  
Sbjct: 839  LKLTQSEKDN---SELRKKLSQLQREMNDSL---SKLNSEKSDLERKLEEISADLSQKEG 892

Query: 639  EVEDKLADISQLQS--DQVCSEIKSVHLEEQIDALSAS---KKELALVIENLKLDKEQLY 693
             ++  +  + +++S  D++  E  S+  + ++D+  A    K E+A + E+ ++  ++L 
Sbjct: 893  MLKKAMDSLKKMKSKLDKLEEEKSSLENQMKVDSEKAETDRKSEIAKINEDFEIKFDKLK 952

Query: 694  GTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGI 753
              +++  N  E   N+L+   ++ +   D  +K    K+S++ ++I HEE ++I  +  +
Sbjct: 953  KQLEEANNSLEKKENELEE-AKKALLRNDTEQKAEFAKLSKM-SEIAHEENARIAKEKAL 1010

Query: 754  DAKIQERDLYIENIES--ELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQK 811
              K  E  L  EN +   + S  + +   LE+ +  +     +L+++   + + L+ + K
Sbjct: 1011 LTKENE-SLKKENEKQKEDYSNLREKYSELEKEVKDLASEIDTLKKEKQNIETKLENELK 1069

Query: 812  AYSEYT--IQ-EDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQIS 868
              +E +  +Q  D    + A +      +++ L   E +N EL      L EEN  L+ +
Sbjct: 1070 KSNEMSQMLQIADSQKEQSANMQRQIDALKESLNSTEKQNSELISSVSALSEENSKLKNT 1129

Query: 869  LSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDL 928
            +   ++  NA ++K          ++ +Q+++ +L+++++ +  E  +   + +  I+ L
Sbjct: 1130 IEAAKKKVNAEIKK----------NSDFQSKIEELQNSIENLNSEKISQAEKAESSIKSL 1179

Query: 929  EIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNN-IENLNMNVEELNKMNLE 987
            + E ++       D + L+  +E ++  VT  + ++Q+  N  I  +     E  K++++
Sbjct: 1180 QNEISSLKLKISEDDEKLSS-FESSLSQVTAEKEEIQKSLNEEIAKMAEISSEKEKISVQ 1238

Query: 988  LIDKHVQK---QQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVS 1044
            L  +++QK   Q++Q    + +    I +L + L+++  E   L Q  N+  VS      
Sbjct: 1239 L--QNIQKENEQKSQEAIKSSELTKRIEELESSLRKEIMENNNLRQVHND--VSNAEDNK 1294

Query: 1045 DYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEM 1104
              + +  +   ++E  +E  +   KQ ++ +    E  I  + +  +    K+ +   E 
Sbjct: 1295 HLQDENEKLRKEIEESKENFEIAKKQFIEEESAKIEQNIKRKFEASKNSLSKKVESLEEE 1354

Query: 1105 NIPKTEGMIISSTI-EPMSDDANNVDXXXXXXXXXXXXLK--VQEEEEFIQERSVLQEQS 1161
            N    + +  S  +   +S   +  D            L    +   + I ER + QE+ 
Sbjct: 1355 NRNLQKSISDSEKVTRNLSAKVSEFDQINRQNSELKQQLSHFTKRHNDLIAEREITQEEC 1414

Query: 1162 AKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKS 1201
             +   + +    K+ +LE    +L      +    N  KS
Sbjct: 1415 LRSQHQAEILTKKVSELEAKLEKLQSEADPSSNSRNSTKS 1454



 Score = 72.1 bits (169), Expect = 1e-10
 Identities = 138/668 (20%), Positives = 279/668 (41%), Gaps = 64/668 (9%)

Query: 67   VSKRIKEHRKATAELLGRPFVPGISESLANTLKQKEI-LMEKIKQYKELSKRSSTTIVRX 125
            + K +++ +K  +EL  +  +    +S+     Q E+ L +  K   EL K+ S  + R 
Sbjct: 805  LQKILEKFKKENSELHSK--LDFSEDSIEKIKSQSELKLTQSEKDNSELRKKLSQ-LQRE 861

Query: 126  XXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQE-KINEKDQ 184
                              +  +S  + +K+  L      +K M++ +  L+E K + ++Q
Sbjct: 862  MNDSLSKLNSEKSDLERKLEEISADLSQKEGMLKKAMDSLKKMKSKLDKLEEEKSSLENQ 921

Query: 185  IIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLK-DI 243
            +     KA T                 +  K+Q+ +   +    E E ++ K+ LL+ D 
Sbjct: 922  MKVDSEKAETDRKSEIAKINEDFEIKFDKLKKQLEEANNSLEKKENELEEAKKALLRNDT 981

Query: 244  ESKD--VRISSL----EEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAK 297
            E K    ++S +     E N  +   +  ++ E+  L +E E+              L K
Sbjct: 982  EQKAEFAKLSKMSEIAHEENARIAKEKALLTKENESLKKENEKQKEDYSNLREKYSELEK 1041

Query: 298  QSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELE-NKLATMGTES 356
            +  + + E  T  +EK ++E     EL K  E+ + L  QI  + KE   N    +    
Sbjct: 1042 EVKDLASEIDTLKKEKQNIETKLENELKKSNEMSQML--QIADSQKEQSANMQRQIDALK 1099

Query: 357  KAVSSPSKKGSPLISRKSGRNTA-SKMK----SPWSQLSSE-TLNQDTDKKI-------- 402
            ++++S  K+ S LIS  S  +   SK+K    +   ++++E   N D   KI        
Sbjct: 1100 ESLNSTEKQNSELISSVSALSEENSKLKNTIEAAKKKVNAEIKKNSDFQSKIEELQNSIE 1159

Query: 403  --NKNEIA---KLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQ 457
              N  +I+   K E  I+SL  ++   +  ISE D                  + +++  
Sbjct: 1160 NLNSEKISQAEKAESSIKSLQNEISSLKLKISEDDEKLSSFESSL--SQVTAEKEEIQKS 1217

Query: 458  QHMEGPSLIHVGTNTEDVN-EIAKVQEQLKQELNDEIKDVNVKDLIEKLKSA-------E 509
             + E   +  + +  E ++ ++  +Q++ +Q+  + IK   +   IE+L+S+        
Sbjct: 1218 LNEEIAKMAEISSEKEKISVQLQNIQKENEQKSQEAIKSSELTKRIEELESSLRKEIMEN 1277

Query: 510  EQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNF--SKVSDSNKEIVRLTEEL--- 564
              + Q+++++  A  N      N KL+ K+++++ +NF  +K     +E  ++ + +   
Sbjct: 1278 NNLRQVHNDVSNAEDNKHLQDENEKLR-KEIEESKENFEIAKKQFIEEESAKIEQNIKRK 1336

Query: 565  -----HHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEME--NLAETRLK-AI 616
                 + LS+KV  LEEE  NLQ  + D +    +  ++  K+ E +  N   + LK  +
Sbjct: 1337 FEASKNSLSKKVESLEEENRNLQKSISDSEK---VTRNLSAKVSEFDQINRQNSELKQQL 1393

Query: 617  SLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKK 676
            S    +  DL+ E  I Q++    + +   +++  S+    E K   L+ + D  S S+ 
Sbjct: 1394 SHFTKRHNDLIAEREITQEECLRSQHQAEILTKKVSE---LEAKLEKLQSEADPSSNSRN 1450

Query: 677  ELALVIEN 684
                +  N
Sbjct: 1451 STKSIDPN 1458



 Score = 66.9 bits (156), Expect = 4e-09
 Identities = 121/696 (17%), Positives = 278/696 (39%), Gaps = 48/696 (6%)

Query: 919  VQKKKEIEDLEIE-FNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMN 977
            +Q++KE +D++++ F   +     +K+VL  +     E++ +  +Q+ E K  I+ L + 
Sbjct: 38   MQQEKEAKDMKLQAFENMVSEITNEKEVLQRQLATLNEHLQKKNSQISEAKTYIKRLAIE 97

Query: 978  VEELNKMNL--ELI------------DKHVQKQQTQSPDYTEQYINEINKLNALLKQKDE 1023
             E+L + N   ELI            +  V +++       ++ +  I KL    ++KD+
Sbjct: 98   NEKLKRNNEMEELILAFDEDRKKYEREIEVLRKRADGDGIVDELLQNITKLEKENEEKDQ 157

Query: 1024 EIIALNQ-KINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQ 1082
             I       + +   S++   SD +   A+F +++ N+++E+  + +         EELQ
Sbjct: 158  IIQQYKGGSLFSGLKSFIQQSSD-DDPTAKFKSEIANLKKELYLLKRNKSTDSPQEEELQ 216

Query: 1083 ILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXL 1142
                 Q+   +  +E       N   ++G   S  +    D   N              L
Sbjct: 217  QPPTPQEQPKEPQREENPKPSEN---SKGFFSSLKLPKAEDPEKNAHLPKMLLGGNASNL 273

Query: 1143 KVQEEEEFIQE---------RSVLQEQSAKLNT--ELQECYTKIIQLETLNTE-LTGHDV 1190
            K +       E         +S  Q +    +T  E +    K         E +    +
Sbjct: 274  KPESTTRLTDELFPDFSTAGKSPEQPKFGDFSTASEKENISPKFDDFSAATEETMLISPM 333

Query: 1191 VNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADF 1250
             ++   + ++   ++   EN+    +   L++  S  +     EI +L + + +  EA  
Sbjct: 334  QDKNNSDLMQFTPQKSKDENEIFFLSPEPLKNDSSEKIHALESEIQKLKQDNKSLEEA-- 391

Query: 1251 QKTEHELRVQLSAFESKYEQLLDSVQSSTQ---EETNKIVTMEQVTSLQNKLQDKEEHLR 1307
                +  +  +   E+  EQL   +    Q   E ++     E +  L+ ++Q+KE   +
Sbjct: 392  LSLVNSTKSDIKELENVIEQLQGEIAEKDQKIKELSSSKENDEILQELEVQIQEKENISK 451

Query: 1308 NLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSI 1367
            +LQ+K A+ I   E    E+E    +                      + +   + ++  
Sbjct: 452  SLQKK-AEEIEMKEKENKELEQVIDSLKTEIDSLTKENEKLNKACERASDAATNLSKERD 510

Query: 1368 LNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLEL-KDSEIYQKTHEYTIT 1426
            + ++E N  + +              ++ + E K+ ++    +L ++++  +  +E    
Sbjct: 511  MIVDEMNKDINEKE----EEIQNNLSKIKELEQKIKDIETDKDLTQNNKSEEIINELQNK 566

Query: 1427 LTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVK 1486
            +     +   + Q++ E E+    L+  K  E+ I  L+     N  +  + E +I+ ++
Sbjct: 567  IQNNLSKIRKLEQKIKELEEANAQLSNNKSEEI-INELQNEIQNNLSKIRELEQKIKELE 625

Query: 1487 LIEELNVKITESVS-LNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQN 1545
              +  N K  E+++ L  ++A+  + +E+   + N +   +E  E +I  L  +   LQN
Sbjct: 626  STQLSNNKSDETINQLEVEIAKNKETIEKINKENNYLHKKVEETEKQINLLETDKNKLQN 685

Query: 1546 MV---RASSSKIQKHVSFASDTKQGRDEQLDNTMNK 1578
            MV     S S ++  +S  S+  + + E+L+ ++ +
Sbjct: 686  MVNELETSKSDLEAKISENSNEDKQQIEKLEESIKE 721


>UniRef50_A0EHN8 Cluster: Chromosome undetermined scaffold_97, whole
            genome shotgun sequence; n=1; Paramecium tetraurelia|Rep:
            Chromosome undetermined scaffold_97, whole genome shotgun
            sequence - Paramecium tetraurelia
          Length = 1252

 Score =  157 bits (381), Expect = 2e-36
 Identities = 246/1187 (20%), Positives = 506/1187 (42%), Gaps = 117/1187 (9%)

Query: 445  KDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEK 504
            + TL  + Q   QQ  E    + +  +  ++ +   +QE  KQ    E   + V  L  +
Sbjct: 29   QSTLFNRDQQSVQQMREQIRQLKMQLSKTNLEKETAIQENNKQTRELERVQIYVTQLEAR 88

Query: 505  LKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEEL 564
            +K  EE +  +  + +A  K  + ++  H   LKQ      +     D N E   L  ++
Sbjct: 89   IKMLEESL--IAQQTEAERK--LTLQKQHFEYLKQSTIERQSTGMQRDFNLEKNDLEIQI 144

Query: 565  HHLSQKVAELEEEKGNLQL--HLVDY-DSGRMIES-------------DVYKKMIEMEN- 607
              L Q++ ELEE+   +    H+  Y D  R I+S               ++KM EM+  
Sbjct: 145  KLLKQRIVELEEQLQKVTSIDHMSGYEDLQRQIDSLTLQLMSQKGQERQFFEKMQEMQKQ 204

Query: 608  LAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQ 667
            L  T  K   L+ S K ++ + +  +    ++++D      QL+ +++  +++  H    
Sbjct: 205  LQITTSKYDQLVHSSKLEIEEYVEKITLLSNQLKDSQDYTEQLEDEKLTQQLQLSH---- 260

Query: 668  IDALSASKKELALVIENLKLDKEQLY---GTIKDLENDKEDIMNKLQNYIQENMDLTDKL 724
                 A  +   L I+ +K++K+  +     ++ LE+ +    N+L N   +N+      
Sbjct: 261  -QVFLAYNEIERLQIKIVKINKKMKFIEESHVQQLEDRQHQFENQL-NLRSQNLQKGSNE 318

Query: 725  EKMSAE-KISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEE 783
             K+S E KIS L  ++   EQ   Q +  +  K Q+ D   + ++ E  K K +     E
Sbjct: 319  LKISYELKISNLQLQLQEREQMIEQLKLELKQKQQKIDELTKQLDQERQKNKQQF----E 374

Query: 784  SIAV-MEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQL- 841
            S  V + D + + ++   +L +  +++     +   ++D ++NR+   +++ +    QL 
Sbjct: 375  SFTVQIRDHKNTSDKAYAELQTNSRDQILKLQQQKQEQDSVLNRIKAELENQKTQNSQLQ 434

Query: 842  -----LEIEHENKELQKKNQIL---LEENQ-----------------NLQISLSDMQQHY 876
                 L+ E+E    Q ++QI    LE N+                  LQ  L   QQ Y
Sbjct: 435  NQINQLQSEYEYMRQQYESQIANLTLEINRLKTQLQQISGKSQQSLDELQYQLEASQQQY 494

Query: 877  NALVEKANRTDLAESESTK-YQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQ 935
              L+E+  +   + S+  + Y+ +++ L+  L + T++   L  +  KE E    EFN+ 
Sbjct: 495  QQLIEQQQQLQNSVSKKNELYENEIKQLKQKLTQATNDLNNLKNESDKEKE----EFNST 550

Query: 936  IESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQK 995
            ++   +  +++ +K +     ++QL+  LQ+     E+ +  V +L ++ +  + + +Q+
Sbjct: 551  LQDYSQQFQLMEKKLKDKENELSQLKKTLQQ---TTESYSEKVTQL-ELEINQLQQQLQQ 606

Query: 996  QQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTT 1055
            Q TQ     +    +  KL   +K+++ EI  L Q I   + +    +S  E +L++   
Sbjct: 607  QSTQFTSQLKNSEKDKEKLKQTIKERETEISQLKQTIKTMEENSTITISQLEIQLSKLQQ 666

Query: 1056 KLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIIS 1115
            + +N ++E Q+   Q    KQ  +  Q  + E  ++I E++  K   E ++   E M+ S
Sbjct: 667  QYQNSQQEQQQQKNQF--QKQIQQMTQT-INELKERISEIQLEKEQLENSL--NESMLKS 721

Query: 1116 STIEPMSDDANNVDXXXXXXXXXXXXLKVQEEE--EFIQERSVLQEQSAKLNTEL--QEC 1171
            S      D    +             +K +E +  +  Q+   LQE+  +L  E+  QE 
Sbjct: 722  SNSN--KDLQRQIQLLQKQIQEYEIRIKFEENKGSDLNQQLESLQEELEQLKLEIKNQER 779

Query: 1172 YTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQR 1231
              + ++ +  + +L    ++ Q+Q   L+ KL  +  ++D+L +   E   +     +Q 
Sbjct: 780  DKEKLKSQLKDQQLQYEQLLKQKQ--DLEQKLSIITQQHDDLTNEYNEFYMNQQQQQEQL 837

Query: 1232 GFEIAELWKQ--HLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTM 1289
               I E  KQ  +  Q+   F++   +L  Q+     + E+         Q  + K+  +
Sbjct: 838  QGNIQEKDKQIKNANQQINQFKQKISDLERQIIQMTHEIEERDTKFSELEQNNSMKLQKL 897

Query: 1290 EQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXX 1349
                  Q +   ++E L   + K   + +Q E    E++ EKV                 
Sbjct: 898  NNTIDQQKRQNQEDEKL--WKSKLTQLSDQHEERERELQQEKVDLQQKLEFQL------- 948

Query: 1350 XDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQL 1409
                 + +  KQ  EQ +  +  ++ QL+ S               ND + K + +  Q 
Sbjct: 949  ----NQLKKSKQETEQRLSQLQLKHDQLENS-------YEDIQREFNDLQDKYVIIQQQF 997

Query: 1410 ELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHEN 1469
                 EI Q   ++ +       +F+ ++  L   E ++  L  + +S LA  +    EN
Sbjct: 998  SSLTIEI-QLLQKFKLDTNDNELKFQALKDSL---ESQLRLLQTKYDSLLASEQHLQDEN 1053

Query: 1470 ANHYETMQKESEIERVKLIEELNVKI-TESVSLNKQVAELNKALEEEVAKTNEMQTALEN 1528
                + +++++ I R+K +E+  +K+ TE+VSL  +   + +  +E  AK  ++ +    
Sbjct: 1054 ----KKLEEQNNI-RIKQLEDFRLKLDTETVSL-AEYETVKQERDESTAKNFQLSSQALK 1107

Query: 1529 QEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNT 1575
             + E+  L  EI NL++ ++   +++Q   +FA   +   + Q + T
Sbjct: 1108 DKSELQKLRREIENLKDDIKTKENEVQDAYNFAQSRQTTGNLQKNET 1154



 Score =  124 bits (299), Expect = 2e-26
 Identities = 228/1278 (17%), Positives = 537/1278 (42%), Gaps = 116/1278 (9%)

Query: 222  QENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQX 281
            Q++   M  + +  K +L K    K+  I    +  + LE  +  ++   +++   LE+ 
Sbjct: 37   QQSVQQMREQIRQLKMQLSKTNLEKETAIQENNKQTRELERVQIYVTQLEARIKM-LEES 95

Query: 282  XXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANM--TELTKKIELLEHLNCQIR 339
                         L KQ  E   +   E +  G     N+   +L  +I+LL+    ++ 
Sbjct: 96   LIAQQTEAERKLTLQKQHFEYLKQSTIERQSTGMQRDFNLEKNDLEIQIKLLKQRIVELE 155

Query: 340  QTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTD 399
            +  +++ +     G E       S     +  +   R    KM+    QL   T   D  
Sbjct: 156  EQLQKVTSIDHMSGYEDLQRQIDSLTLQLMSQKGQERQFFEKMQEMQKQLQITTSKYDQL 215

Query: 400  KKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQH 459
               +K EI +    I  L+  L D +    + +             + L  QLQL HQ  
Sbjct: 216  VHSSKLEIEEYVEKITLLSNQLKDSQDYTEQLED------------EKLTQQLQLSHQVF 263

Query: 460  MEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQI-TQLNDE 518
            +               NEI ++Q ++ + +N ++K +  +  +++L+  + Q   QLN  
Sbjct: 264  LA-------------YNEIERLQIKIVK-INKKMKFIE-ESHVQQLEDRQHQFENQLNLR 308

Query: 519  IDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEK 578
                 K   ++K +++LK+  +Q       ++ +  + I +L  EL    QK+ EL +  
Sbjct: 309  SQNLQKGSNELKISYELKISNLQL------QLQEREQMIEQLKLELKQKQQKIDELTK-- 360

Query: 579  GNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYD 638
               QL      + +  ES      +++ +   T  KA + L++   D + +L   +Q+ D
Sbjct: 361  ---QLDQERQKNKQQFESFT----VQIRDHKNTSDKAYAELQTNSRDQILKLQQQKQEQD 413

Query: 639  EVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSAS----KKELALVIENLKLDKEQLYG 694
             V +++   ++L++ +     ++  L+ QI+ L +     +++    I NL L+  +L  
Sbjct: 414  SVLNRIK--AELENQKT----QNSQLQNQINQLQSEYEYMRQQYESQIANLTLEINRLKT 467

Query: 695  TIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGID 754
             ++ +    +  +++LQ  ++ +     +L +   +++   ++K N   +++I+    + 
Sbjct: 468  QLQQISGKSQQSLDELQYQLEASQQQYQQLIEQQ-QQLQNSVSKKNELYENEIKQ---LK 523

Query: 755  AKIQERDLYIENIESELSKYK----SRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQ 810
             K+ +    + N+++E  K K    S +    +   +ME +    E +  QL   LQ+  
Sbjct: 524  QKLTQATNDLNNLKNESDKEKEEFNSTLQDYSQQFQLMEKKLKDKENELSQLKKTLQQTT 583

Query: 811  KAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLS 870
            ++YSE   Q +  +N+L       + +++Q  +   + K  +K  + L +  +  +  +S
Sbjct: 584  ESYSEKVTQLELEINQL------QQQLQQQSTQFTSQLKNSEKDKEKLKQTIKERETEIS 637

Query: 871  DMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEI 930
             ++Q    + E +  T       ++ + QL  L+   +    E Q    Q +K+I+ +  
Sbjct: 638  QLKQTIKTMEENSTIT------ISQLEIQLSKLQQQYQNSQQEQQQQKNQFQKQIQQMTQ 691

Query: 931  EFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELID 990
              N +++  I + ++  E+ E ++      E+ L+   +N ++L   ++ L K  ++  +
Sbjct: 692  TIN-ELKERISEIQLEKEQLENSLN-----ESMLKSSNSN-KDLQRQIQLLQKQ-IQEYE 743

Query: 991  KHVQKQQTQSPDYTEQYIN---EINKLNALLKQKDEEIIALNQKINNAQVSYMSMVS--- 1044
              ++ ++ +  D  +Q  +   E+ +L   +K ++ +   L  ++ + Q+ Y  ++    
Sbjct: 744  IRIKFEENKGSDLNQQLESLQEELEQLKLEIKNQERDKEKLKSQLKDQQLQYEQLLKQKQ 803

Query: 1045 DYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEM 1104
            D E KL+  T + +++  E        ++ +Q  E+LQ  ++E+D QIK   +    F+ 
Sbjct: 804  DLEQKLSIITQQHDDLTNEYNEF---YMNQQQQQEQLQGNIQEKDKQIKNANQQINQFKQ 860

Query: 1105 NIPKTEGMIISST--IEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSA 1162
             I   E  II  T  IE      + ++               Q++ +  ++  + + +  
Sbjct: 861  KISDLERQIIQMTHEIEERDTKFSELEQNNSMKLQKLNNTIDQQKRQNQEDEKLWKSKLT 920

Query: 1163 KLNTELQECYTKIIQLETLNTELTGHDVVNQ--EQINQLKSKLEQLNTENDNLLSTVAEL 1220
            +L+ + +E   + +Q E ++ +      +NQ  +   + + +L QL  ++D L ++  ++
Sbjct: 921  QLSDQHEE-RERELQQEKVDLQQKLEFQLNQLKKSKQETEQRLSQLQLKHDQLENSYEDI 979

Query: 1221 RSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQ 1280
            +   +   D+  + I +   Q  +    + Q  + + ++  +  E K++ L DS++S  +
Sbjct: 980  QREFNDLQDK--YVIIQ---QQFSSLTIEIQLLQ-KFKLDTNDNELKFQALKDSLESQLR 1033

Query: 1281 EETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXX 1340
                K    + + + +  LQD+    + L+E+    I Q+E  R +++ E V+       
Sbjct: 1034 LLQTK---YDSLLASEQHLQDEN---KKLEEQNNIRIKQLEDFRLKLDTETVSLAEYETV 1087

Query: 1341 XXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQ--LKKSSXXXXXXXXXXXXRVNDA 1398
                      + +  +Q+ K   E   L    EN +  +K               R    
Sbjct: 1088 KQERDESTAKNFQLSSQALKDKSELQKLRREIENLKDDIKTKENEVQDAYNFAQSRQTTG 1147

Query: 1399 EAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQ---LVEYEKRIEDLTYEK 1455
              +  E T  L++++ ++  +   +   +  +N+E + +++Q   L     +++  + + 
Sbjct: 1148 NLQKNE-TDMLKIENQKLLNQIKGFETKIIIQNEEIDKLKRQNEELTLQNSQLKKYSDKL 1206

Query: 1456 ESELAILRLKMHENANHY 1473
            ++E    +L   ++ N Y
Sbjct: 1207 QAEYDQCQLDYKDHINKY 1224



 Score = 94.3 bits (224), Expect = 2e-17
 Identities = 159/756 (21%), Positives = 333/756 (44%), Gaps = 80/756 (10%)

Query: 143  DVTHLSN-TIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXX 201
            D+ +L N + KEK+   S LQ   +  +     L++K NE  Q+ +   + T        
Sbjct: 532  DLNNLKNESDKEKEEFNSTLQDYSQQFQLMEKKLKDKENELSQLKKTLQQTTESYSEKVT 591

Query: 202  XXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLE 261
                      +  +QQ T+    F +     + +K++L + I+ ++  IS L++  K +E
Sbjct: 592  QLELEINQLQQQLQQQSTQ----FTSQLKNSEKDKEKLKQTIKERETEISQLKQTIKTME 647

Query: 262  AARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANM 321
                  ++  S+L  +L +                +Q  + S +E+ + + +   +I  M
Sbjct: 648  E---NSTITISQLEIQLSKL---------------QQQYQNSQQEQQQQKNQFQKQIQQM 689

Query: 322  TELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKG-SPLISRKSGRNTAS 380
            T+     EL E ++ +I+   ++LEN L     ES   SS S K     I     +    
Sbjct: 690  TQTIN--ELKERIS-EIQLEKEQLENSL----NESMLKSSNSNKDLQRQIQLLQKQIQEY 742

Query: 381  KMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXX 440
            +++  + +     LNQ  +    + E+ +L++ I++  +D   KE + S+          
Sbjct: 743  EIRIKFEENKGSDLNQQLESL--QEELEQLKLEIKNQERD---KEKLKSQLKDQQLQYEQ 797

Query: 441  XXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLK---QELNDEIKDVN 497
                K  L  +L +  QQH +    +    N   +N+  + QEQL+   QE + +IK+ N
Sbjct: 798  LLKQKQDLEQKLSIITQQHDD----LTNEYNEFYMNQ-QQQQEQLQGNIQEKDKQIKNAN 852

Query: 498  --VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNK 555
              +    +K+   E QI Q+  EI+  +    +++ N+ +KL+++  TID   + +  ++
Sbjct: 853  QQINQFKQKISDLERQIIQMTHEIEERDTKFSELEQNNSMKLQKLNNTIDQQKRQNQEDE 912

Query: 556  EI--VRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRL 613
            ++   +LT+      ++  EL++EK +LQ  L ++   ++ +S    K    + L++ +L
Sbjct: 913  KLWKSKLTQLSDQHEERERELQQEKVDLQQKL-EFQLNQLKKS----KQETEQRLSQLQL 967

Query: 614  KAISLLESQKFDLVQELHILQQKYDEVEDKLA----DISQLQSDQVCSEIKSVHLEEQID 669
            K    LE+   D+ +E + LQ KY  ++ + +    +I  LQ  ++ +    +  +   D
Sbjct: 968  KH-DQLENSYEDIQREFNDLQDKYVIIQQQFSSLTIEIQLLQKFKLDTNDNELKFQALKD 1026

Query: 670  ALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSA 729
            +L +  + L    ++L   ++ L    K LE      + +L+++         +L K+  
Sbjct: 1027 SLESQLRLLQTKYDSLLASEQHLQDENKKLEEQNNIRIKQLEDF---------RL-KLDT 1076

Query: 730  EKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVME 789
            E +S  LA+    +Q + ++     AK  +        +SEL K +  I  L++ I   E
Sbjct: 1077 ETVS--LAEYETVKQERDEST----AKNFQLSSQALKDKSELQKLRREIENLKDDIKTKE 1130

Query: 790  DR---RYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEH 846
            +     Y+  +     G+ LQ+ +    +  I+  +L+N++        +  +++ +++ 
Sbjct: 1131 NEVQDAYNFAQSRQTTGN-LQKNETDMLK--IENQKLLNQIKGFETKIIIQNEEIDKLKR 1187

Query: 847  ENKELQKKNQILLEENQNLQISLSDMQQHYNALVEK 882
            +N+EL  +N  L + +  LQ      Q  Y   + K
Sbjct: 1188 QNEELTLQNSQLKKYSDKLQAEYDQCQLDYKDHINK 1223



 Score = 83.8 bits (198), Expect = 4e-14
 Identities = 182/895 (20%), Positives = 396/895 (44%), Gaps = 85/895 (9%)

Query: 92   ESLANTLKQKEI----LMEKIKQYKELSKR---SSTTIVRXXXXXXXXXXXXXXXQLGD- 143
            E L   LKQK+     L +++ Q ++ +K+   S T  +R                  D 
Sbjct: 342  EQLKLELKQKQQKIDELTKQLDQERQKNKQQFESFTVQIRDHKNTSDKAYAELQTNSRDQ 401

Query: 144  VTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXX 203
            +  L    +E+D+ L+ ++ +++  +T    LQ +IN+    ++++ +            
Sbjct: 402  ILKLQQQKQEQDSVLNRIKAELENQKTQNSQLQNQINQ----LQSEYEYMRQQYESQIAN 457

Query: 204  XXXXXXXXEDTKQQMT-KMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEA 262
                    +   QQ++ K Q++   ++ + +  +Q+  + IE +    +S+ + N+L E 
Sbjct: 458  LTLEINRLKTQLQQISGKSQQSLDELQYQLEASQQQYQQLIEQQQQLQNSVSKKNELYEN 517

Query: 263  ARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMT 322
               EI     KL Q                      +++   ++   +E+K   +   ++
Sbjct: 518  ---EIKQLKQKLTQATNDLNNLKNESDKEKEEF-NSTLQDYSQQFQLMEKKLKDKENELS 573

Query: 323  ELTKKI-ELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASK 381
            +L K + +  E  + ++ Q   E+      +  +S   +S  K       ++  + T  +
Sbjct: 574  QLKKTLQQTTESYSEKVTQLELEINQLQQQLQQQSTQFTSQLKNSEK--DKEKLKQTIKE 631

Query: 382  MKSPWSQLSS--ETLNQDTDKKINKNEI--AKLEMVIQSLNKDLVDKEYVISEKDTXXXX 437
             ++  SQL    +T+ +++   I++ EI  +KL+   Q+  ++   ++    ++      
Sbjct: 632  RETEISQLKQTIKTMEENSTITISQLEIQLSKLQQQYQNSQQEQQQQKNQFQKQIQQMTQ 691

Query: 438  XXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDV-NEIAKVQEQLKQ-ELNDEIKD 495
                   + + I QL+ E  ++    S++    + +D+  +I  +Q+Q+++ E+  + ++
Sbjct: 692  TINELKERISEI-QLEKEQLENSLNESMLKSSNSNKDLQRQIQLLQKQIQEYEIRIKFEE 750

Query: 496  VNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKS---NHKLKLKQMQKTIDNF-SKVS 551
                DL ++L+S +E++ QL  EI    ++  K+KS   + +L+ +Q+ K   +   K+S
Sbjct: 751  NKGSDLNQQLESLQEELEQLKLEIKNQERDKEKLKSQLKDQQLQYEQLLKQKQDLEQKLS 810

Query: 552  DSNKEIVRLTEELHHLSQKVAELEEE-KGNLQLHLVDY-DSGRMIE------SDVYKKMI 603
               ++   LT E +       + +E+ +GN+Q       ++ + I       SD+ +++I
Sbjct: 811  IITQQHDDLTNEYNEFYMNQQQQQEQLQGNIQEKDKQIKNANQQINQFKQKISDLERQII 870

Query: 604  EMENLAETRLKAISLLESQKFDLVQELH--ILQQKYDEVED------KLADIS------- 648
            +M +  E R    S LE      +Q+L+  I QQK    ED      KL  +S       
Sbjct: 871  QMTHEIEERDTKFSELEQNNSMKLQKLNNTIDQQKRQNQEDEKLWKSKLTQLSDQHEERE 930

Query: 649  -QLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIM 707
             +LQ ++V  + K   LE Q++ L  SK+E    +  L+L  +QL  + +D++ +  D+ 
Sbjct: 931  RELQQEKVDLQQK---LEFQLNQLKKSKQETEQRLSQLQLKHDQLENSYEDIQREFNDLQ 987

Query: 708  NKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQT-QFGIDAKIQERDLYIEN 766
            +K     Q+   LT +++ +   K+        ++ + K Q  +  ++++++      ++
Sbjct: 988  DKYVIIQQQFSSLTIEIQLLQKFKLD------TNDNELKFQALKDSLESQLRLLQTKYDS 1041

Query: 767  IESELSKYKSRICRLEES----IAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDE 822
            + +     +    +LEE     I  +ED R  L+ +   L  Y   KQ+   E T +  +
Sbjct: 1042 LLASEQHLQDENKKLEEQNNIRIKQLEDFRLKLDTETVSLAEYETVKQER-DESTAKNFQ 1100

Query: 823  LVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEK 882
            L ++   L D     E Q L  E EN     K+ I  +EN+ +Q + +  Q        +
Sbjct: 1101 LSSQ--ALKDKS---ELQKLRREIEN----LKDDIKTKENE-VQDAYNFAQSRQTTGNLQ 1150

Query: 883  ANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIE 937
             N TD+ + E+ K   Q++  E+ +  I +E    I + K++ E+L ++ N+Q++
Sbjct: 1151 KNETDMLKIENQKLLNQIKGFETKI-IIQNEE---IDKLKRQNEELTLQ-NSQLK 1200



 Score = 59.3 bits (137), Expect = 9e-07
 Identities = 99/551 (17%), Positives = 217/551 (39%), Gaps = 49/551 (8%)

Query: 1059 NMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTI 1118
            N +E     S  +  +KQ +     L       +++++E     +M + KT  +   + I
Sbjct: 7    NEKEPYSLFSPSVNLNKQSDNTQSTLFNRDQQSVQQMREQIRQLKMQLSKTN-LEKETAI 65

Query: 1119 EPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQL 1178
            +  +     ++            +K+ EE        + Q+  A+    LQ+ + + ++ 
Sbjct: 66   QENNKQTRELERVQIYVTQLEARIKMLEES------LIAQQTEAERKLTLQKQHFEYLKQ 119

Query: 1179 ETLNTELTGHDVVNQEQINQLKSKLE-QLNTENDNLLSTVAELRSSISSAVDQRGFE--- 1234
             T+  + TG     Q   N  K+ LE Q+      ++    +L+  ++S     G+E   
Sbjct: 120  STIERQSTGM----QRDFNLEKNDLEIQIKLLKQRIVELEEQLQK-VTSIDHMSGYEDLQ 174

Query: 1235 --IAELWKQHLAQR--EADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTME 1290
              I  L  Q ++Q+  E  F +   E++ QL    SKY+QL+ S +   +E       +E
Sbjct: 175  RQIDSLTLQLMSQKGQERQFFEKMQEMQKQLQITTSKYDQLVHSSKLEIEEY------VE 228

Query: 1291 QVTSLQNKLQDKEEHLRNLQEK----YADVINQIEILRSEIEDEKVAFXXXXXXXXXXXX 1346
            ++T L N+L+D +++   L+++       + +Q+ +  +EIE  ++              
Sbjct: 229  KITLLSNQLKDSQDYTEQLEDEKLTQQLQLSHQVFLAYNEIERLQIKIVKINKKMKFIEE 288

Query: 1347 XXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXR-----------V 1395
                 L      ++        N+ + + +LK S                         +
Sbjct: 289  SHVQQLEDRQHQFENQLNLRSQNLQKGSNELKISYELKISNLQLQLQEREQMIEQLKLEL 348

Query: 1396 NDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEK-RIEDLTYE 1454
               + K+ ELT QL+ +  +  Q+   +T+ +    +  +    +L    + +I  L  +
Sbjct: 349  KQKQQKIDELTKQLDQERQKNKQQFESFTVQIRDHKNTSDKAYAELQTNSRDQILKLQQQ 408

Query: 1455 KESELAIL-RLKMHENANHYETMQKESEIERVKLIEELNVKITES--VSLNKQVAELNKA 1511
            K+ + ++L R+K        +  Q +++I +++   E   +  ES   +L  ++  L   
Sbjct: 409  KQEQDSVLNRIKAELENQKTQNSQLQNQINQLQSEYEYMRQQYESQIANLTLEINRLKTQ 468

Query: 1512 LEEEVAKT----NEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQG 1567
            L++   K+    +E+Q  LE  + +   L ++   LQN V   +   +  +         
Sbjct: 469  LQQISGKSQQSLDELQYQLEASQQQYQQLIEQQQQLQNSVSKKNELYENEIKQLKQKLTQ 528

Query: 1568 RDEQLDNTMNK 1578
                L+N  N+
Sbjct: 529  ATNDLNNLKNE 539


>UniRef50_Q02224 Cluster: Centromeric protein E; n=8; Eutheria|Rep:
            Centromeric protein E - Homo sapiens (Human)
          Length = 2663

 Score =  157 bits (381), Expect = 2e-36
 Identities = 269/1344 (20%), Positives = 582/1344 (43%), Gaps = 122/1344 (9%)

Query: 298  QSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGT--E 355
            Q +E     K E+  +   +I  + E     + LE++   +  + + +E+      T  +
Sbjct: 571  QDLENELSSKVELLREKEDQIKKLQEYIDS-QKLENIKMDLSYSLESIEDPKQMKQTLFD 629

Query: 356  SKAVSSPSKKGSPLISRKSGRNTASKMK---SPWSQLSSETLNQDTDKKINKNEIAKLEM 412
            ++ V+  +K+ S  + R        KMK   + + Q+ ++     +  +  K     LE 
Sbjct: 630  AETVALDAKRESAFL-RSENLELKEKMKELATTYKQMENDIQLYQSQLEAKKKMQVDLEK 688

Query: 413  VIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHME-GPSLIHVGTN 471
             +QS   ++     +I  K            GK   I  LQ E  + +E   +L      
Sbjct: 689  ELQSAFNEITKLTSLIDGKVPKDLLCNLELEGK---ITDLQKELNKEVEENEALREEVIL 745

Query: 472  TEDVNEIAKVQEQLKQELNDEIKDVNV----KD-LIEKLKSAEEQITQLNDEIDAANKNM 526
              ++  +    E+L++E+ D+ +++++    KD L  ++   E ++  L +EI     ++
Sbjct: 746  LSELKSLPSEVERLRKEIQDKSEELHIITSEKDKLFSEVVHKESRVQGLLEEIGKTKDDL 805

Query: 527  IKVKSNHKLKLKQMQ--KTI--DNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQ 582
               +SN+K   ++ Q  KT+  D   K     +E  R+ +E+ +LS++  + +   G L+
Sbjct: 806  ATTQSNYKSTDQEFQNFKTLHMDFEQKYKMVLEENERMNQEIVNLSKEAQKFDSSLGALK 865

Query: 583  LHLVDYDSGRMIES--DVYKKMIEMENLAE---TRLKAISLLESQKFDLVQELHILQQKY 637
              L  Y +  + E   +V +++ EME L E    R   +  +E +K  + ++L    ++ 
Sbjct: 866  TEL-SYKTQELQEKTREVQERLNEMEQLKEQLENRDSPLQTVEREKTLITEKLQQTLEEV 924

Query: 638  DEVEDKLADISQLQSD-QVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTI 696
              +  +  D+ QLQ   Q+  +     + + ++    ++++L   +E+LK  +E +  T+
Sbjct: 925  KTLTQEKDDLKQLQESLQIERDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQETI-NTL 983

Query: 697  KDLENDK-------EDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQT 749
            K   +++       E+   + ++  Q+ M   DK + + A+    L A +   E   I+ 
Sbjct: 984  KSKISEEVSRNLHMEENTGETKDEFQQKMVGIDKKQDLEAKNTQTLTADVKDNEI--IEQ 1041

Query: 750  QFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEK 809
            Q  I + IQE++   + +ES +++ +     L+E+I +  + +  L    D+L    +  
Sbjct: 1042 QRKIFSLIQEKNELQQMLESVIAEKEQLKTDLKENIEMTIENQEELRLLGDELKKQQEIV 1101

Query: 810  QKAYSEYTIQEDEL---VNRLAVLMDH-----DRVVEKQ--LLEIEHENKELQKK-NQI- 857
             +  +    +E EL    +RLA + +       ++ EKQ  LL ++ E  E+QKK N+I 
Sbjct: 1102 AQEKNHAIKKEGELSRTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEIE 1161

Query: 858  -LLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESN-------LKR 909
             L  E +N +++L  M+     L +K N         TK +  L++L+ +       L+ 
Sbjct: 1162 NLKNELKNKELTLEHMETERLELAQKLNENYEEVKSITKERKVLKELQKSFETERDHLRG 1221

Query: 910  ITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEK--NIEYVTQLEAQLQE- 966
               E +   +Q K+E++   I      E+    ++ ++EK  +  N + + +   +LQE 
Sbjct: 1222 YIREIEATGLQTKEELKIAHIHLKEHQETIDELRRSVSEKTAQIINTQDLEKSHTKLQEE 1281

Query: 967  --YKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKL--NALLKQKD 1022
                +  + L  NV+++++    + +  +  +Q+ + D T     E+ +L  N   ++  
Sbjct: 1282 IPVLHEEQELLPNVKKVSETQETMNELELLTEQSTTKDSTTLARIEMERLRLNEKFQESQ 1341

Query: 1023 EEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQ 1082
            EEI +L ++ +N +    ++   ++         L  ++E   +  +Q L+ K+ + E  
Sbjct: 1342 EEIKSLTKERDNLKTIKEALEVKHDQLKEHIRETLAKIQESQSK-QEQSLNMKEKDNETT 1400

Query: 1083 ILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXL 1142
             +V E + Q K      L  E+     E + +S  ++   D+  +V              
Sbjct: 1401 KIVSEME-QFKPKDSALLRIEI-----EMLGLSKRLQESHDEMKSV-------------- 1440

Query: 1143 KVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQ--INQLK 1200
              +E+++  + + VLQ +S +L   ++E   K   LET       H  + +++  IN+L+
Sbjct: 1441 -AKEKDDLQRLQEVLQSESDQLKENIKEIVAK--HLETEEELKVAHCCLKEQEETINELR 1497

Query: 1201 SKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQ 1260
              L +  TE    +ST+ +   +I+  +  +  EI E  +Q   ++ ++ Q+  +EL+ Q
Sbjct: 1498 VNLSEKETE----ISTIQKQLEAINDKLQNKIQEIYEKEEQLNIKQISEVQENVNELK-Q 1552

Query: 1261 LSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQI 1320
                    +  L S++S   E TN++   E    +Q  +++KEE ++ +QE      +Q+
Sbjct: 1553 FKEHRKAKDSALQSIESKMLELTNRL--QESQEEIQIMIKEKEE-MKRVQEALQIERDQL 1609

Query: 1321 -----EILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENA 1375
                 EI+    E ++  +                ++    + + + Q+ ++ NI  EN 
Sbjct: 1610 KENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQF-ETQKLNLENIETENI 1668

Query: 1376 QLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFE 1435
            +L +                +D  +    +   L+++  ++ +   E      ++ +E +
Sbjct: 1669 RLTQILHENLEEMRSVTKERDDLRS----VEETLKVERDQLKENLRETITRDLEKQEELK 1724

Query: 1436 NVRQQLVEYEKRIEDL---TYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELN 1492
             V   L E+++ I+ L     EK +E++     M ++  H     K  ++   K+ EEL 
Sbjct: 1725 IVHMHLKEHQETIDKLRGIVSEKTNEIS----NMQKDLEHSNDALKAQDL---KIQEELR 1777

Query: 1493 VKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEI-TNLQNMV--RA 1549
            +         + + +L   + E+  K + MQ  LEN   ++     E+  N   ++  + 
Sbjct: 1778 IAHMHLKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQELKANEHQLITLKK 1837

Query: 1550 SSSKIQKHVSFASD-TKQGRDEQL 1572
              ++ QK VS      KQ +D+ L
Sbjct: 1838 DVNETQKKVSEMEQLKKQIKDQSL 1861



 Score =  140 bits (339), Expect = 3e-31
 Identities = 239/1313 (18%), Positives = 573/1313 (43%), Gaps = 106/1313 (8%)

Query: 328  IELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWS 387
            +E  E +N +I   +KE +   +++G     +S  +++    +  K+ R    ++     
Sbjct: 837  LEENERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQE----LQEKT-REVQERLNE-ME 890

Query: 388  QLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDT 447
            QL  +  N+D+  +  + E     ++ + L + L + + +  EKD            +D 
Sbjct: 891  QLKEQLENRDSPLQTVEREKT---LITEKLQQTLEEVKTLTQEKDDLKQLQESLQIERDQ 947

Query: 448  L------IAQLQLEHQQHMEGPSLIHVGTNTEDVNEI-AKVQEQLKQELNDEIKDVNVKD 500
            L         + ++ Q+ +   +L  +  + E +N + +K+ E++ + L+ E      KD
Sbjct: 948  LKSDIHDTVNMNIDTQEQLRN-ALESLKQHQETINTLKSKISEEVSRNLHMEENTGETKD 1006

Query: 501  L-------IEKLKSAEEQITQL-------NDEIDAANKNMIKVKSNHKLKLKQMQKTIDN 546
                    I+K +  E + TQ        N+ I+   K    ++  ++L+ + ++  I  
Sbjct: 1007 EFQQKMVGIDKKQDLEAKNTQTLTADVKDNEIIEQQRKIFSLIQEKNELQ-QMLESVIAE 1065

Query: 547  FSKVSDSNKEIVRLT----EELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKM 602
              ++    KE + +T    EEL  L  ++ + +E     + H +  + G +  S    ++
Sbjct: 1066 KEQLKTDLKENIEMTIENQEELRLLGDELKKQQEIVAQEKNHAIKKE-GEL--SRTCDRL 1122

Query: 603  IEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVED-------KLADISQLQSDQV 655
             E+E   + + + +   + Q  ++ +E+  +Q+K +E+E+       K   +  ++++++
Sbjct: 1123 AEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKNKELTLEHMETERL 1182

Query: 656  CSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLE----NDKEDIMNKLQ 711
                K     E++ +++  +K L  + ++ + +++ L G I+++E      KE++  K+ 
Sbjct: 1183 ELAQKLNENYEEVKSITKERKVLKELQKSFETERDHLRGYIREIEATGLQTKEEL--KIA 1240

Query: 712  N-YIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESE 770
            + +++E+ +  D+L +  +EK +++   IN ++  K  T      K+QE ++ + + E E
Sbjct: 1241 HIHLKEHQETIDELRRSVSEKTAQI---INTQDLEKSHT------KLQE-EIPVLHEEQE 1290

Query: 771  LSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVL 830
            L     ++   +E++  +E        K     + ++ ++   +E   +  E +  L   
Sbjct: 1291 LLPNVKKVSETQETMNELELLTEQSTTKDSTTLARIEMERLRLNEKFQESQEEIKSLTKE 1350

Query: 831  MDHDRVVEKQLLEIEHEN-KELQKKNQILLEENQNLQISLSDMQQHYNA---LVEKANRT 886
             D+ + + K+ LE++H+  KE  ++    ++E+Q+ Q    +M++  N    +V +  + 
Sbjct: 1351 RDNLKTI-KEALEVKHDQLKEHIRETLAKIQESQSKQEQSLNMKEKDNETTKIVSEMEQF 1409

Query: 887  DLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVL 946
               +S   + + ++  L   L+  +H+    + ++K +++ L+    ++ +    + K +
Sbjct: 1410 KPKDSALLRIEIEMLGLSKRLQE-SHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEI 1468

Query: 947  NEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQ 1006
              K+ +  E +      L+E +  I  L +N+ E  +  +  I K ++    +  +  ++
Sbjct: 1469 VAKHLETEEELKVAHCCLKEQEETINELRVNLSE-KETEISTIQKQLEAINDKLQNKIQE 1527

Query: 1007 YINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQR 1066
               +  +LN     + +E +   ++    + +  S +   ESK+ + T +L+  +EE+Q 
Sbjct: 1528 IYEKEEQLNIKQISEVQENVNELKQFKEHRKAKDSALQSIESKMLELTNRLQESQEEIQI 1587

Query: 1067 VSKQLLDSKQHNEELQILVREQDDQIKE-LKETKLTFEMNIPKTEGMIISSTIEPMSDDA 1125
            + K+  + K+  E LQI    + DQ+KE  KE     + +  K    +  + +    +  
Sbjct: 1588 MIKEKEEMKRVQEALQI----ERDQLKENTKEIVAKMKESQEKEYQFLKMTAVNETQEKM 1643

Query: 1126 NNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTEL 1185
              ++            L+  E E  I+   +L E   ++ +  +E        ETL  E 
Sbjct: 1644 CEIEHLKEQFETQKLNLENIETEN-IRLTQILHENLEEMRSVTKERDDLRSVEETLKVER 1702

Query: 1186 TGHDVVNQEQINQLKSKLEQLNTENDNLLS---TVAELRSSISSAVDQRGFEIAELWKQH 1242
                   +E I +   K E+L   + +L     T+ +LR  +S   ++      +L   +
Sbjct: 1703 DQLKENLRETITRDLEKQEELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSN 1762

Query: 1243 LAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQN-KLQD 1301
             A +  D  K + ELR+     + + E + D ++    E+T+K+  M++     N KLQ+
Sbjct: 1763 DALKAQDL-KIQEELRIAHMHLKEQQETI-DKLRGIVSEKTDKLSNMQKDLENSNAKLQE 1820

Query: 1302 KEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQ 1361
            K + L+  + +   +   +   + ++ + +                   +L    + ++ 
Sbjct: 1821 KIQELKANEHQLITLKKDVNETQKKVSEMEQLKKQIKDQSLTLSKLEIENLNLAQELHEN 1880

Query: 1362 MQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTH 1421
            ++E    ++ +E   L++               + + +A+ LE+  Q ELK + +  K H
Sbjct: 1881 LEEMK--SVMKERDNLRRVEETLKLERDQLKESLQETKARDLEI--QQELKTARMLSKEH 1936

Query: 1422 EYTI-----TLTQRNDEFENVRQQL----VEYEKRIEDLTYEKESELAILRLKMHENANH 1472
            + T+      ++++  +  ++++ L     E +K+I++L   ++ EL +LR+K   N +H
Sbjct: 1937 KETVDKLREKISEKTIQISDIQKDLDKSKDELQKKIQEL---QKKELQLLRVKEDVNMSH 1993

Query: 1473 YETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIE 1532
                +K +E+E++K   E N      +   +   +L+++LEE      E       +E  
Sbjct: 1994 ----KKINEMEQLKKQFEPNYLCKCEMDNFQLTKKLHESLEEIRIVAKERDELRRIKESL 2049

Query: 1533 IVTLNDEITNLQNMVR--ASSSKIQKHVSFASDTKQGRDEQLDNTMN--KELL 1581
             +  +  I  L+ M+     + +++      SD +Q   E L    +  KELL
Sbjct: 2050 KMERDQFIATLREMIARDRQNHQVKPEKRLLSDGQQHLMESLREKCSRIKELL 2102



 Score =  121 bits (291), Expect = 2e-25
 Identities = 268/1319 (20%), Positives = 574/1319 (43%), Gaps = 175/1319 (13%)

Query: 105  MEKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNALSVL--Q 162
            ME++K+  E ++ S    V                ++  +T   + +K+   +L +   Q
Sbjct: 889  MEQLKEQLE-NRDSPLQTVEREKTLITEKLQQTLEEVKTLTQEKDDLKQLQESLQIERDQ 947

Query: 163  VKMKIMETTIL--DLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTK 220
            +K  I +T  +  D QE++    + ++   +                    E+T +   +
Sbjct: 948  LKSDIHDTVNMNIDTQEQLRNALESLKQHQETINTLKSKISEEVSRNLHMEENTGETKDE 1007

Query: 221  MQENFIAMEAEWKDEKQRLLKDIESKDVRISSLE-EANKLLEAARFEISLEHSKLAQELE 279
             Q+  + +     D+KQ    D+E+K+ +  + + + N+++E  R   SL   K   EL+
Sbjct: 1008 FQQKMVGI-----DKKQ----DLEAKNTQTLTADVKDNEIIEQQRKIFSLIQEK--NELQ 1056

Query: 280  QXXXXXXXXXXXXXXLAKQSIEPSCEEKTEI-----EEKGSLEIANMT---------ELT 325
            Q                K++IE + E + E+     E K   EI             EL+
Sbjct: 1057 QMLESVIAEKEQLKTDLKENIEMTIENQEELRLLGDELKKQQEIVAQEKNHAIKKEGELS 1116

Query: 326  KKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSP 385
            +  + L  +  ++++ +++L+ K   +    + +S   KK + + + K   N     +  
Sbjct: 1117 RTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEIENLK---NELKNKELT 1173

Query: 386  WSQLSSETLNQDTDKKINKN-----EIAKLEMVIQSLNKDL-VDKEYVISEKDTXXXXXX 439
               + +E L  +  +K+N+N      I K   V++ L K    +++++   +        
Sbjct: 1174 LEHMETERL--ELAQKLNENYEEVKSITKERKVLKELQKSFETERDHL---RGYIREIEA 1228

Query: 440  XXXXGKDTL-IAQLQL-EHQQHM-EGPSLIHVGT----NTEDVNEI-AKVQEQL-----K 486
                 K+ L IA + L EHQ+ + E    +   T    NT+D+ +   K+QE++     +
Sbjct: 1229 TGLQTKEELKIAHIHLKEHQETIDELRRSVSEKTAQIINTQDLEKSHTKLQEEIPVLHEE 1288

Query: 487  QELNDEIKDVN-VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTID 545
            QEL   +K V+  ++ + +L+   EQ T   D    A   M +++ N K +  + Q+ I 
Sbjct: 1289 QELLPNVKKVSETQETMNELELLTEQSTT-KDSTTLARIEMERLRLNEKFQ--ESQEEIK 1345

Query: 546  NFSKVSDSNKEIVRLTEELH-----HLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYK 600
            + +K  D+ K I    E  H     H+ + +A+++E +   +  L    + +  +++  K
Sbjct: 1346 SLTKERDNLKTIKEALEVKHDQLKEHIRETLAKIQESQSKQEQSL----NMKEKDNETTK 1401

Query: 601  KMIEMENLAETRLKAISLLESQKFDL---VQELHILQQKYDEVED---KLADISQLQSDQ 654
             + EME   + +  A+  +E +   L   +QE H   +   + +D   +L ++ Q +SDQ
Sbjct: 1402 IVSEMEQF-KPKDSALLRIEIEMLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQ 1460

Query: 655  VCSEIKSV---HLE--EQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNK 709
            +   IK +   HLE  E++       KE    I  L+++  +    I  ++   E I +K
Sbjct: 1461 LKENIKEIVAKHLETEEELKVAHCCLKEQEETINELRVNLSEKETEISTIQKQLEAINDK 1520

Query: 710  LQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIES 769
            LQN IQE   + +K E+++ ++ISE+   +N  +Q K   +         +D  +++IES
Sbjct: 1521 LQNKIQE---IYEKEEQLNIKQISEVQENVNELKQFKEHRK--------AKDSALQSIES 1569

Query: 770  ELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAV 829
            ++ +  +R+   +E I +M   +  ++R  + L    Q ++    E T    E+V +   
Sbjct: 1570 KMLELTNRLQESQEEIQIMIKEKEEMKRVQEAL----QIERDQLKENT---KEIVAK--- 1619

Query: 830  LMDHDRVVEKQLLEIEHENKELQKKNQI--LLEENQNLQISLSDMQQHYNALVEKANRTD 887
             M   +  E Q L++   N+  +K  +I  L E+ +  +++L +++   N  + +    +
Sbjct: 1620 -MKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQKLNLENIETE-NIRLTQILHEN 1677

Query: 888  LAESES-TKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVL 946
            L E  S TK +  LR +E  LK          V++ +  E+L       +E    + K++
Sbjct: 1678 LEEMRSVTKERDDLRSVEETLK----------VERDQLKENLRETITRDLEKQ-EELKIV 1726

Query: 947  NEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQ 1006
            +   +++ E + +L   + E  N I N+  ++E  N   L+  D  +Q++   +  + ++
Sbjct: 1727 HMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDA-LKAQDLKIQEELRIAHMHLKE 1785

Query: 1007 YINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQR 1066
                I+KL  ++ +K +       K++N Q        D E+  A    KL+   +E++ 
Sbjct: 1786 QQETIDKLRGIVSEKTD-------KLSNMQ-------KDLENSNA----KLQEKIQELKA 1827

Query: 1067 VSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDAN 1126
               QL+  K+   E Q  V E +   K++K+  LT  ++  + E + ++  +    ++  
Sbjct: 1828 NEHQLITLKKDVNETQKKVSEMEQLKKQIKDQSLT--LSKLEIENLNLAQELHENLEEMK 1885

Query: 1127 NVDXXXXXXXXXXXXLKVQEEE--EFIQE---RSVLQEQSAK----LNTELQECYTKI-- 1175
            +V             LK++ ++  E +QE   R +  +Q  K    L+ E +E   K+  
Sbjct: 1886 SVMKERDNLRRVEETLKLERDQLKESLQETKARDLEIQQELKTARMLSKEHKETVDKLRE 1945

Query: 1176 ------IQLETLNTELTGHDVVNQEQINQL-KSKLEQLNTEND-NL----LSTVAELRSS 1223
                  IQ+  +  +L       Q++I +L K +L+ L  + D N+    ++ + +L+  
Sbjct: 1946 KISEKTIQISDIQKDLDKSKDELQKKIQELQKKELQLLRVKEDVNMSHKKINEMEQLKKQ 2005

Query: 1224 IS----SAVDQRGFEIAELWKQHL------AQREADFQKTEHELRVQLSAFESKYEQLLD 1273
                     +   F++ +   + L      A+   + ++ +  L+++   F +   +++ 
Sbjct: 2006 FEPNYLCKCEMDNFQLTKKLHESLEEIRIVAKERDELRRIKESLKMERDQFIATLREMIA 2065

Query: 1274 SVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEIL-RSEIEDEK 1331
              + + Q +  K +  +    L   L++K   ++ L ++Y+++ +  E L R  ++ EK
Sbjct: 2066 RDRQNHQVKPEKRLLSDGQQHLMESLREKCSRIKELLKRYSEMDDHYECLNRLSLDLEK 2124



 Score =  111 bits (267), Expect = 2e-22
 Identities = 234/1125 (20%), Positives = 487/1125 (43%), Gaps = 131/1125 (11%)

Query: 473  EDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSN 532
            E+V+   + Q   K +L   +++   KDL++K+++  E+I  L   +  ++   ++ +  
Sbjct: 360  EEVSLETRAQAMEKDQLAQLLEE---KDLLQKVQN--EKIENLTRMLVTSSSLTLQQELK 414

Query: 533  HKLKLKQMQKTIDNFSKVSDSNKEI-----VRLTEELHHLS-QKVAELEEEK-GNLQLHL 585
             K K +++   +   +K+ +SN          +T + H LS   + E++E       +  
Sbjct: 415  AKRK-RRVTWCLGKINKMKNSNYADQFNIPTNITTKTHKLSINLLREIDESVCSESDVFS 473

Query: 586  VDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLA 645
               D+   IE +   K++  EN+ E+ L +   L +   +LV +   L+ + +E+E KL 
Sbjct: 474  NTLDTLSEIEWNPATKLLNQENI-ESELNS---LRADYDNLVLDYEQLRTEKEEMELKLK 529

Query: 646  DISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKED 705
            + + L   +          E Q+    ++ K L    E    D E    +  +L  +KED
Sbjct: 530  EKNDLDEFEALERKTKKDQEMQLIHEISNLKNLVKHREVYNQDLENELSSKVELLREKED 589

Query: 706  IMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQF-----GIDAKIQER 760
             + KLQ YI      + KLE +  + +S  L  I   +Q K QT F      +DAK +  
Sbjct: 590  QIKKLQEYID-----SQKLENIKMD-LSYSLESIEDPKQMK-QTLFDAETVALDAKRESA 642

Query: 761  DLYIENIE--SELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTI 818
             L  EN+E   ++ +  +   ++E  I + + +   LE K        +E Q A++E T 
Sbjct: 643  FLRSENLELKEKMKELATTYKQMENDIQLYQSQ---LEAKKKMQVDLEKELQSAFNEIT- 698

Query: 819  QEDELVNRLAVLMDHDRVVEKQLLEIEHENK--ELQKKNQILLEENQNLQ---ISLSDMQ 873
                   +L  L+D  +V +  L  +E E K  +LQK+    +EEN+ L+   I LS+++
Sbjct: 699  -------KLTSLID-GKVPKDLLCNLELEGKITDLQKELNKEVEENEALREEVILLSELK 750

Query: 874  QHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTL---IVQKKKEIEDLEI 930
                             SE  + + +++D    L  IT E   L   +V K+  ++ L  
Sbjct: 751  S--------------LPSEVERLRKEIQDKSEELHIITSEKDKLFSEVVHKESRVQGLLE 796

Query: 931  EFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELID 990
            E         +D     +   K+ +         QE++ N + L+M+ E+  KM LE  +
Sbjct: 797  EI-----GKTKDDLATTQSNYKSTD---------QEFQ-NFKTLHMDFEQKYKMVLEENE 841

Query: 991  KHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKL 1050
            +  Q+    S +  +++ + +  L   L  K +E   L +K    Q   ++ +   + +L
Sbjct: 842  RMNQEIVNLSKE-AQKFDSSLGALKTELSYKTQE---LQEKTREVQ-ERLNEMEQLKEQL 896

Query: 1051 AQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTE 1110
                + L+ +E E   ++++L   +Q  EE++ L +E+DD +K+L+E+ L  E +  K++
Sbjct: 897  ENRDSPLQTVEREKTLITEKL---QQTLEEVKTLTQEKDD-LKQLQES-LQIERDQLKSD 951

Query: 1111 GMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQE 1170
                 +      +   N              LK +  EE +     ++E + +   E Q+
Sbjct: 952  IHDTVNMNIDTQEQLRNALESLKQHQETINTLKSKISEE-VSRNLHMEENTGETKDEFQQ 1010

Query: 1171 CYTKIIQ---LETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSA 1227
                I +   LE  NT+    DV + E I Q +     +  +N+     + ++  S+ + 
Sbjct: 1011 KMVGIDKKQDLEAKNTQTLTADVKDNEIIEQQRKIFSLIQEKNE-----LQQMLESVIAE 1065

Query: 1228 VDQRGFEIAELWKQHLA-QREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKI 1286
             +Q   ++ E  +  +  Q E      E + + ++ A E  +    +   S T +   ++
Sbjct: 1066 KEQLKTDLKENIEMTIENQEELRLLGDELKKQQEIVAQEKNHAIKKEGELSRTCDRLAEV 1125

Query: 1287 VTMEQVTSLQNKLQDKEEHLRNLQEKYADV---INQIEILRSEIEDEKVAFXXXXXXXXX 1343
               E++     +LQ+K++ L N+QE+ +++   IN+IE L++E++++++           
Sbjct: 1126 --EEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKNKELTLEHMETERLE 1183

Query: 1344 XXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVL 1403
                     +  N++Y++++     +I +E   LK+               + + EA  L
Sbjct: 1184 LA-------QKLNENYEEVK-----SITKERKVLKELQKSFETERDHLRGYIREIEATGL 1231

Query: 1404 ELTHQLELKDSEIYQKTHEYTI-----TLTQRNDEFENVRQQLVEYEKRIEDLTYEKESE 1458
            +     ELK + I+ K H+ TI     +++++  +  N +     + K  E++    E +
Sbjct: 1232 QTKE--ELKIAHIHLKEHQETIDELRRSVSEKTAQIINTQDLEKSHTKLQEEIPVLHEEQ 1289

Query: 1459 LAILRLK----MHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEE 1514
              +  +K      E  N  E + ++S  +    +  + +   E + LN++  E  + ++ 
Sbjct: 1290 ELLPNVKKVSETQETMNELELLTEQSTTKDSTTLARIEM---ERLRLNEKFQESQEEIKS 1346

Query: 1515 EVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVS 1559
               + + ++T  E  E++   L + I      ++ S SK ++ ++
Sbjct: 1347 LTKERDNLKTIKEALEVKHDQLKEHIRETLAKIQESQSKQEQSLN 1391



 Score =  106 bits (255), Expect = 4e-21
 Identities = 205/1020 (20%), Positives = 437/1020 (42%), Gaps = 108/1020 (10%)

Query: 140  QLGDVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXX 199
            Q+ +V    N +K+           ++ +E+ +L+L  ++ E  + I+   K        
Sbjct: 1539 QISEVQENVNELKQFKEHRKAKDSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRV 1598

Query: 200  XXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKL 259
                        E+TK+ + KM+E+    E E++  K   + + + K   I  L+E  + 
Sbjct: 1599 QEALQIERDQLKENTKEIVAKMKES---QEKEYQFLKMTAVNETQEKMCEIEHLKEQFET 1655

Query: 260  LEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLA---------KQSIEPSCEEKT-- 308
             +     I  E+ +L Q L +              L          +  ++ +  E    
Sbjct: 1656 QKLNLENIETENIRLTQILHENLEEMRSVTKERDDLRSVEETLKVERDQLKENLRETITR 1715

Query: 309  EIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSP 368
            ++E++  L+I +M  L +  E ++ L   + +   E+ N    +   + A+ +   K   
Sbjct: 1716 DLEKQEELKIVHM-HLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQE 1774

Query: 369  LIS-----RKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQ-------- 415
             +       K  + T  K++   S+ + +  N   D +   N  AKL+  IQ        
Sbjct: 1775 ELRIAHMHLKEQQETIDKLRGIVSEKTDKLSNMQKDLE---NSNAKLQEKIQELKANEHQ 1831

Query: 416  --SLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTL-IAQLQLEHQQHM---EGPSLIHVG 469
              +L KD+ + +  +SE +               L I  L L  + H    E  S++   
Sbjct: 1832 LITLKKDVNETQKKVSEMEQLKKQIKDQSLTLSKLEIENLNLAQELHENLEEMKSVMKER 1891

Query: 470  TNTEDVNEIAKVQ-EQLKQELND-EIKDVNVKDLIEKL----KSAEEQITQLNDEIDAAN 523
             N   V E  K++ +QLK+ L + + +D+ ++  ++      K  +E + +L ++I    
Sbjct: 1892 DNLRRVEETLKLERDQLKESLQETKARDLEIQQELKTARMLSKEHKETVDKLREKISEKT 1951

Query: 524  KNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQL 583
              +  ++ +      ++QK I    K      +++R+ E+++   +K+ E+E+ K   + 
Sbjct: 1952 IQISDIQKDLDKSKDELQKKIQELQK---KELQLLRVKEDVNMSHKKINEMEQLKKQFEP 2008

Query: 584  HLV---DYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKY--D 638
            + +   + D+ ++ +  +++ + E+  +A+ R +   + ES K +  Q +  L++    D
Sbjct: 2009 NYLCKCEMDNFQLTKK-LHESLEEIRIVAKERDELRRIKESLKMERDQFIATLREMIARD 2067

Query: 639  EVEDKLADISQLQSD----------QVCSEIKSV-----HLEEQIDALSASKKELALVIE 683
                ++    +L SD          + CS IK +      +++  + L+    +L   IE
Sbjct: 2068 RQNHQVKPEKRLLSDGQQHLMESLREKCSRIKELLKRYSEMDDHYECLNRLSLDLEKEIE 2127

Query: 684  NLKLDKEQLY--GTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINH 741
              ++ K+  Y    +  ++ ++ + +NK +      MD  D++EK       ELL KI H
Sbjct: 2128 FHRIMKKLKYVLSYVTKIKEEQHECINKFE------MDFIDEVEKQK-----ELLIKIQH 2176

Query: 742  EEQS-KIQTQFGIDAKI-QERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKA 799
             +Q   + ++   D K+ Q  DL+IE I  + S+ +    + E    V+ +R+   +   
Sbjct: 2177 LQQDCDVPSRELRDLKLNQNMDLHIEEILKDFSESEFPSIKTEFQ-QVLSNRKEMTQFLE 2235

Query: 800  DQLGSYLQ-EK-----QKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEI----EHENK 849
            + L +    EK     QK         +   NR+  +M+     E++   I    E + K
Sbjct: 2236 EWLNTRFDIEKLKNGIQKENDRICQVNNFFNNRIIAIMNESTEFEERSATISKEWEQDLK 2295

Query: 850  ELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQ-LRDLESNL- 907
             L++KN+ L +  Q L+ SL+   Q  N   +  N+     S +T+  T+ +R+LE++L 
Sbjct: 2296 SLKEKNEKLFKNYQTLKTSLASGAQ-VNPTTQD-NKNPHVTSRATQLTTEKIRELENSLH 2353

Query: 908  --KRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQ-L 964
              K      ++ I++ +KE+E +  +   ++++ + +     EK ++ I+ +    A   
Sbjct: 2354 EAKESAMHKESKIIKMQKELE-VTNDIIAKLQAKVHESNKCLEKTKETIQVLQDKVALGA 2412

Query: 965  QEYKNNIENLNMNVE--ELNKM-NLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQK 1021
            + YK  IE+L M +   +L KM N +  +K +   +  + +Y ++ I  + + N    Q+
Sbjct: 2413 KPYKEEIEDLKMKLVKIDLEKMKNAKEFEKEISATKA-TVEYQKEVIRLLRE-NLRRSQQ 2470

Query: 1022 DEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEEL 1081
             ++   +++   + Q S   +     S + Q  TK   ++ E  R+ K++   KQ NE+L
Sbjct: 2471 AQDTSVISEH-TDPQPSNKPLTCGGGSGIVQ-NTKALILKSEHIRLEKEISKLKQQNEQL 2528



 Score =  100 bits (240), Expect = 3e-19
 Identities = 199/982 (20%), Positives = 409/982 (41%), Gaps = 91/982 (9%)

Query: 153  EKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXE 212
            E +  L V    +K  E TI +L+  ++EK+  I    K                    E
Sbjct: 1474 ETEEELKVAHCCLKEQEETINELRVNLSEKETEISTIQKQLEAINDKLQNKIQEIYEKEE 1533

Query: 213  DTK-QQMTKMQENFIAMEA--EWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISL 269
                +Q++++QEN   ++   E +  K   L+ IESK      LE  N+L E+   EI +
Sbjct: 1534 QLNIKQISEVQENVNELKQFKEHRKAKDSALQSIESK-----MLELTNRLQESQE-EIQI 1587

Query: 270  EHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGS-LEIANMTELTKKI 328
                + +E E+              L + + E   + K   E++   L++  + E  +K+
Sbjct: 1588 ----MIKEKEEMKRVQEALQIERDQLKENTKEIVAKMKESQEKEYQFLKMTAVNETQEKM 1643

Query: 329  ELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSG--RNTASKMKSPW 386
              +EHL  Q       LEN + T       +   + +    ++++    R+    +K   
Sbjct: 1644 CEIEHLKEQFETQKLNLEN-IETENIRLTQILHENLEEMRSVTKERDDLRSVEETLKVER 1702

Query: 387  SQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDK-EYVISEKDTXXXXXXXXXXGK 445
             QL  E L +   + + K E  K+  +    +++ +DK   ++SEK              
Sbjct: 1703 DQLK-ENLRETITRDLEKQEELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHS 1761

Query: 446  DTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVN-----VKD 500
            +  +    L+ Q+ +    + H+    E ++++  +  +   +L++  KD+      +++
Sbjct: 1762 NDALKAQDLKIQEELRIAHM-HLKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQE 1820

Query: 501  LIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRL 560
             I++LK+ E Q+  L  +++   K   KV    +LK KQ++      SK+   N   + L
Sbjct: 1821 KIQELKANEHQLITLKKDVNETQK---KVSEMEQLK-KQIKDQSLTLSKLEIEN---LNL 1873

Query: 561  TEELHHLSQKVAELEEEKGNLQL--HLVDYDSGRMIESDVYKKMIEMENLAETRLKAISL 618
             +ELH   +++  + +E+ NL+     +  +  ++ ES    K  ++E   +  LK   +
Sbjct: 1874 AQELHENLEEMKSVMKERDNLRRVEETLKLERDQLKESLQETKARDLE--IQQELKTARM 1931

Query: 619  LESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKEL 678
            L  +  + V +L       +++ +K   IS +Q D   S+ +   L+++I  L   KKEL
Sbjct: 1932 LSKEHKETVDKLR------EKISEKTIQISDIQKDLDKSKDE---LQKKIQELQ--KKEL 1980

Query: 679  ALVIENLKLDKEQLYGTIKDLENDKEDIM-NKLQNYIQENMDLTDKLEKMSAEKISELLA 737
             L+   +K D    +  I ++E  K+    N L     +N  LT KL + S E+I  ++A
Sbjct: 1981 QLL--RVKEDVNMSHKKINEMEQLKKQFEPNYLCKCEMDNFQLTKKLHE-SLEEI-RIVA 2036

Query: 738  KINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLER 797
            K   +E  +I+    +     ERD +I  +   +++ +       E   + + +++ +E 
Sbjct: 2037 K-ERDELRRIKESLKM-----ERDQFIATLREMIARDRQNHQVKPEKRLLSDGQQHLMES 2090

Query: 798  KADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHD----RVVEKQLLEIEHENKELQK 853
              ++  S ++E  K YSE      E +NRL++ ++ +    R+++K    + +  K  ++
Sbjct: 2091 LREKC-SRIKELLKRYSEMD-DHYECLNRLSLDLEKEIEFHRIMKKLKYVLSYVTKIKEE 2148

Query: 854  KNQIL----------LEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDL 903
            +++ +          +E+ + L I +  +QQ  +    +     L ++     +  L+D 
Sbjct: 2149 QHECINKFEMDFIDEVEKQKELLIKIQHLQQDCDVPSRELRDLKLNQNMDLHIEEILKDF 2208

Query: 904  -ESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEA 962
             ES    I  E Q ++  +K+  + LE   NT+ +          EK +  I+       
Sbjct: 2209 SESEFPSIKTEFQQVLSNRKEMTQFLEEWLNTRFDI---------EKLKNGIQKENDRIC 2259

Query: 963  QLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKD 1022
            Q+  + NN     MN     +     I K  ++      +  E+       L   L    
Sbjct: 2260 QVNNFFNNRIIAIMNESTEFEERSATISKEWEQDLKSLKEKNEKLFKNYQTLKTSLAS-G 2318

Query: 1023 EEIIALNQKINNAQVSYMSM------VSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQ 1076
             ++    Q   N  V+  +       + + E+ L +      + E ++ ++ K+L  +  
Sbjct: 2319 AQVNPTTQDNKNPHVTSRATQLTTEKIRELENSLHEAKESAMHKESKIIKMQKELEVTND 2378

Query: 1077 HNEELQILVREQDDQIKELKET 1098
               +LQ  V E +  +++ KET
Sbjct: 2379 IIAKLQAKVHESNKCLEKTKET 2400



 Score = 79.4 bits (187), Expect = 8e-13
 Identities = 160/827 (19%), Positives = 346/827 (41%), Gaps = 75/827 (9%)

Query: 750  QFGIDAKIQERDLYIENIESE---LSKYKSRICRLEESI--AVMEDRRYSLERKADQLGS 804
            QF   AK  +   Y+  + ++   L +Y+  I  L++ +    +E R  ++E+  DQL  
Sbjct: 321  QFASTAKYMKNTPYVNEVSTDEALLKRYRKEIMDLKKQLEEVSLETRAQAMEK--DQLAQ 378

Query: 805  YLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQN 864
             L+EK        +Q +++ N   +L+    +  +Q L+ + + +      +I   +N N
Sbjct: 379  LLEEKDLLQK---VQNEKIENLTRMLVTSSSLTLQQELKAKRKRRVTWCLGKINKMKNSN 435

Query: 865  LQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKE 924
                  ++  +      K +   L E + +       D+ SN      E +     K   
Sbjct: 436  YADQF-NIPTNITTKTHKLSINLLREIDESVCSES--DVFSNTLDTLSEIEWNPATKLLN 492

Query: 925  IEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNK- 983
             E++E E N+    A  D  VL+  YE+      ++E +L+E KN+++       +  K 
Sbjct: 493  QENIESELNSL--RADYDNLVLD--YEQLRTEKEEMELKLKE-KNDLDEFEALERKTKKD 547

Query: 984  MNLELIDK--HVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMS 1041
              ++LI +  +++        Y +   NE++    LL++K+++I  L + I++ ++  + 
Sbjct: 548  QEMQLIHEISNLKNLVKHREVYNQDLENELSSKVELLREKEDQIKKLQEYIDSQKLENIK 607

Query: 1042 MVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLT 1101
            M   Y  +  +   +++    + + V+   LD+K+ +  L+    E  +++KEL  T   
Sbjct: 608  MDLSYSLESIEDPKQMKQTLFDAETVA---LDAKRESAFLRSENLELKEKMKELATTYKQ 664

Query: 1102 FEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEF---IQERSVLQ 1158
             E +I   +   + +  +   D    +             +  +  ++    ++    + 
Sbjct: 665  MENDIQLYQSQ-LEAKKKMQVDLEKELQSAFNEITKLTSLIDGKVPKDLLCNLELEGKIT 723

Query: 1159 EQSAKLNTELQE---CYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLS 1215
            +   +LN E++E      ++I L  L + L       +++I     +L  + +E D L S
Sbjct: 724  DLQKELNKEVEENEALREEVILLSELKS-LPSEVERLRKEIQDKSEELHIITSEKDKLFS 782

Query: 1216 TVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHE---LRVQLSAFESKYEQLL 1272
             V    S +   +++ G       K  LA  +++++ T+ E    +     FE KY+ +L
Sbjct: 783  EVVHKESRVQGLLEEIG-----KTKDDLATTQSNYKSTDQEFQNFKTLHMDFEQKYKMVL 837

Query: 1273 DSVQSSTQEETNKIVTMEQVTS----LQNKLQDKEEHLRNLQEKYADVINQIEILRSEIE 1328
            +  +   QE  N     ++  S    L+ +L  K + L+    +  + +N++E L+ ++E
Sbjct: 838  EENERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQELQEKTREVQERLNEMEQLKEQLE 897

Query: 1329 DEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXX 1388
            +                      L TE     Q   + +  + +E   LK+         
Sbjct: 898  NRDSPLQTVEREKT---------LITEK---LQQTLEEVKTLTQEKDDLKQLQESLQIER 945

Query: 1389 XXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRI 1448
                  ++D     + +  Q +L+++    K H+ TI  T ++   E V + L   E+  
Sbjct: 946  DQLKSDIHDTVN--MNIDTQEQLRNALESLKQHQETIN-TLKSKISEEVSRNL-HMEENT 1001

Query: 1449 EDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAEL 1508
             +   E + ++  +  K    A + +T+   ++++  ++IE+   KI    SL ++  EL
Sbjct: 1002 GETKDEFQQKMVGIDKKQDLEAKNTQTL--TADVKDNEIIEQQR-KI---FSLIQEKNEL 1055

Query: 1509 NKALEEEVAKTNEMQT--------ALENQEIEIVTLNDEITNLQNMV 1547
             + LE  +A+  +++T         +ENQE E+  L DE+   Q +V
Sbjct: 1056 QQMLESVIAEKEQLKTDLKENIEMTIENQE-ELRLLGDELKKQQEIV 1101



 Score = 53.6 bits (123), Expect = 4e-05
 Identities = 172/851 (20%), Positives = 345/851 (40%), Gaps = 76/851 (8%)

Query: 62   ENAALVSKRIKEHRKATAELLGRPFVPGISESLANTLKQKEILMEKIKQYKELSKRSSTT 121
            E   +V   +KEH++   +L G   V   +  ++N  K  E   + +K  ++L  +    
Sbjct: 1721 EELKIVHMHLKEHQETIDKLRG--IVSEKTNEISNMQKDLEHSNDALKA-QDLKIQEELR 1777

Query: 122  IVRXXXXXXXXXXXXXXXQLGDVTH-LSNTIKEKDNALSVLQVK---MKIMETTILDL-- 175
            I                  + + T  LSN  K+ +N+ + LQ K   +K  E  ++ L  
Sbjct: 1778 IAHMHLKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQELKANEHQLITLKK 1837

Query: 176  -----QEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQE--NFIAM 228
                 Q+K++E +Q+ +     +                  E+ ++  + M+E  N   +
Sbjct: 1838 DVNETQKKVSEMEQLKKQIKDQSLTLSKLEIENLNLAQELHENLEEMKSVMKERDNLRRV 1897

Query: 229  EAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQEL-EQXXXXXXX 287
            E   K E+ +L + ++    R   +++    L+ AR  +S EH +   +L E+       
Sbjct: 1898 EETLKLERDQLKESLQETKARDLEIQQE---LKTARM-LSKEHKETVDKLREKISEKTIQ 1953

Query: 288  XXXXXXXL--AKQSIEPSCEE--KTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNK 343
                   L  +K  ++   +E  K E++     E  NM+   KKI  +E L  Q  + N 
Sbjct: 1954 ISDIQKDLDKSKDELQKKIQELQKKELQLLRVKEDVNMSH--KKINEMEQLKKQF-EPNY 2010

Query: 344  ELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSS---ETLNQDTDK 400
              + ++       K   S  +       R   R     +K    Q  +   E + +D   
Sbjct: 2011 LCKCEMDNFQLTKKLHESLEEIRIVAKERDELRRIKESLKMERDQFIATLREMIARDRQN 2070

Query: 401  KINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHM 460
               K E   L    Q L + L +K   I E               + L   L+ E + H 
Sbjct: 2071 HQVKPEKRLLSDGQQHLMESLREKCSRIKELLKRYSEMDDHYECLNRLSLDLEKEIEFHR 2130

Query: 461  EGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEID 520
                L +V      ++ + K++E+  + +N    +++  D +EK K    +I  L  + D
Sbjct: 2131 IMKKLKYV------LSYVTKIKEEQHECINKF--EMDFIDEVEKQKELLIKIQHLQQDCD 2182

Query: 521  AANKNM--IKVKSNHKLKLKQMQKTIDN---------FSKVSDSNKEIVRLTEELHHLSQ 569
              ++ +  +K+  N  L ++++ K             F +V  + KE+ +  EE  +   
Sbjct: 2183 VPSRELRDLKLNQNMDLHIEEILKDFSESEFPSIKTEFQQVLSNRKEMTQFLEEWLNTRF 2242

Query: 570  KVAELEE--EKGNLQLHLVD-YDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDL 626
             + +L+   +K N ++  V+ + + R+I   +  +  E E  + T  K     E     L
Sbjct: 2243 DIEKLKNGIQKENDRICQVNNFFNNRIIA--IMNESTEFEERSATISKE---WEQDLKSL 2297

Query: 627  VQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASK-KELALVIENL 685
             ++   L + Y  ++  LA  S  Q +    + K+ H+  +   L+  K +EL   +   
Sbjct: 2298 KEKNEKLFKNYQTLKTSLA--SGAQVNPTTQDNKNPHVTSRATQLTTEKIRELENSLHEA 2355

Query: 686  KLDKEQLYGTIKDLENDKE---DIMNKLQNYIQEN---MDLTDKLEKMSAEKISELLAKI 739
            K         I  ++ + E   DI+ KLQ  + E+   ++ T +  ++  +K++ L AK 
Sbjct: 2356 KESAMHKESKIIKMQKELEVTNDIIAKLQAKVHESNKCLEKTKETIQVLQDKVA-LGAKP 2414

Query: 740  NHEEQSKIQTQFGIDAKIQ-ERDLYIENIESELSKYKSRICRLEESIAVM-EDRRYSLER 797
              EE   ++ +     KI  E+    +  E E+S  K+ +   +E I ++ E+ R S + 
Sbjct: 2415 YKEEIEDLKMKL---VKIDLEKMKNAKEFEKEISATKATVEYQKEVIRLLRENLRRSQQA 2471

Query: 798  KADQLGSYLQEKQKAYSEYTIQEDELV--NRLAVLMDHDRV-VEKQLLEIEHENKELQKK 854
            +   + S   + Q +    T      +  N  A+++  + + +EK++ +++ +N++L K+
Sbjct: 2472 QDTSVISEHTDPQPSNKPLTCGGGSGIVQNTKALILKSEHIRLEKEISKLKQQNEQLIKQ 2531

Query: 855  NQILLEENQNL 865
               LL  NQ+L
Sbjct: 2532 KNELLSNNQHL 2542


>UniRef50_Q23D13 Cluster: Viral A-type inclusion protein repeat
            containing protein; n=1; Tetrahymena thermophila
            SB210|Rep: Viral A-type inclusion protein repeat
            containing protein - Tetrahymena thermophila SB210
          Length = 1753

 Score =  157 bits (380), Expect = 3e-36
 Identities = 263/1386 (18%), Positives = 605/1386 (43%), Gaps = 139/1386 (10%)

Query: 249  RISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKT 308
            ++  L+  N+ L+  +  I   + KL QE E               + KQ+     + K 
Sbjct: 358  KVKDLQTLNQQLKQEKQTIDDLNQKLKQENESLKKTGNQLQQEIEQIIKQNKIKEVQNKE 417

Query: 309  EIEEKGSLEIANMTELTKKIEL-----LEHLNCQIRQTNKELENKLATMGTESKAVSSPS 363
            E E +    I  + E  KK +       E +  Q+  T   L+ K   +  E    +S  
Sbjct: 418  EFEAQNK-RIKELDERYKKEKTDYQKQNESIKSQMESTISALQEKNKLLEQERDDANS-K 475

Query: 364  KKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDL-V 422
             KGS +  +++      ++ +   QL+ E       ++I+K +    E +I+ LN ++ +
Sbjct: 476  LKGSQIDMQQTKIKIGEELTTLKRQLTDE-------QQISKQKKENFEKIIEQLNLEIQM 528

Query: 423  DKEYVISEKDTXXXXXXXXXXGKDTLIAQLQ-LEH--QQHMEGPSLIHVGTNTEDVNEIA 479
             K+     ++T           K+    ++Q LE   ++  E    +     TE  N   
Sbjct: 529  QKDASKEFENTISKLNAQSEANKNESQVRIQSLEEVIKKIEEELKCMKESKETETKNLKQ 588

Query: 480  KVQE--QLKQELNDEIKDVN--VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKL 535
            K+ E     ++L D++K      +DL +KL   E + + +  E+D        +K ++ L
Sbjct: 589  KITELETSNKDLGDQLKTKTNETEDLNKKLNDLETENSNMRRELDET------IKKSNSL 642

Query: 536  KLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIE 595
            ++   +++  N  ++ D N+   +  +E+  +  +++ L EE   L+  L          
Sbjct: 643  EILIQEQSTRNSQELKDKNEIFNQSIKEIARVKAEISSLHEENKLLKEQL---------- 692

Query: 596  SDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQV 655
            +  +K+++E + + E +      L  +   L ++  +  ++ D +E  L     +  D +
Sbjct: 693  ATSHKELVETKQIKEEKTVLCVQLSEKLSSLQEQFDVKSEQLDSLEISLKQKQDI-IDGL 751

Query: 656  CSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQ 715
              EI+ +   EQ+ +   SKKE    ++  K   +     I+ L++  +D+ + L+ +  
Sbjct: 752  KEEIEELE-NEQLGSAENSKKEQNSQLQQFKEQTDSFQNEIQQLKSQIQDLESNLK-FKN 809

Query: 716  ENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIEN-IESELSKY 774
            E +   D++ K    +I     KIN E+   ++ Q      ++E+ L ++N +E   +K 
Sbjct: 810  EEIIKQDEIIKNKQNEI-----KINEEKAENVKHQ------LEEKVLSLQNKLEESNNKL 858

Query: 775  KSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQK--AYSEYTIQEDELVNRLAVLMD 832
            K++     + I   +     L ++ + L   L+E +   AY +  +++ E +++  ++ +
Sbjct: 859  KTQEEESAKEIEEAQSSFLKLRQELEVLKLSLEENENNHAYEKQQMEQRE-IDKNVLIEE 917

Query: 833  HDRVVEKQ------LLEIEHENKE-LQKKNQILLEENQNLQISLSDMQQHYNALVEKANR 885
            ++R V +Q      L  ++ +NKE +Q+K++ +LE+ + ++ +   + +  N L ++  +
Sbjct: 918  YERKVREQNQELTSLTAMQRKNKEEIQRKDETILEKEKRIKQNQDKLSEVQNELKKQNQQ 977

Query: 886  TDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIE---DLEIEFNTQIESAIRD 942
             D  + ++ + + +  + E  L+R     +  I QK+++I        E + QI++ +++
Sbjct: 978  LDEYKQQNQQLEERAINAEQELER----EKMQIAQKEEQISLTRKSNEEQSNQIQNFLKE 1033

Query: 943  KKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLN----MNVEELNKMNLELIDKHVQKQQT 998
             + LN K  + +EY+ +LE   +E  + I  LN    +  EE++K  +E + K    + +
Sbjct: 1034 IQELNNKVNEQVEYIAELEQLKEETNSQINELNQEQKLKYEEMHKQ-IEKLQKQCDFKDS 1092

Query: 999  QSPDYTEQYINEIN----KLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFT 1054
            Q     E+  ++      + N+ L +K+E I    Q +  ++    S + D E++  +  
Sbjct: 1093 QYQQLKEELSSQDQAKEERSNSTLTEKEERI----QNLEKSKFDLESSLQDKENECERLV 1148

Query: 1055 TKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMII 1114
             ++ N +++++++   +L S Q    L+  ++ ++++I  +K++++T  M   +      
Sbjct: 1149 QQVNNFQQQVKKLKDDILTSTQETATLKKSIQLKENEIL-VKQSEITKLMRESQESIDSK 1207

Query: 1115 SSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLN-------TE 1167
            +   E ++ D +N++            LK Q +    QE S L+E + +         +E
Sbjct: 1208 NQFKESLTRDIHNLNSNIQSKEREIIQLKSQVQT-LNQELSELKESNNQFQIIIDQAESE 1266

Query: 1168 LQECYTKII--QLETLNTELTGHDVVN--QEQINQLKSKLEQLNTEN-DNLLSTVAE--- 1219
              E     +  + E    E T  D     +E+I  L+ KL+ L  ++ + ++ ++ E   
Sbjct: 1267 KNEAQRTSLSNKAELDEIEQTYQDAQQKLEEKIRSLQEKLQLLEQKSKEEMMMSLKENSD 1326

Query: 1220 LRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSST 1279
            L+  ++   +Q   + ++  K+H    +AD QK+  E + Q+S   SK E+L  S  + T
Sbjct: 1327 LKGKLNMFEEQHKLKYSDYEKKH----QAD-QKSIEEQKKQISTQLSKIEELELSQAAIT 1381

Query: 1280 QEETN---KIVTMEQVTSLQNKLQDKEEH-----LRNLQEKYADVINQIEILRSEIED-- 1329
            Q+  N   ++ + E+V +  N    + +H     +  L++K   + ++   L++++ +  
Sbjct: 1382 QQLENLKAELKSKEEVINGLNNQDQQNQHSKDGQIETLKQKLLSLESEKLELQNQVNELE 1441

Query: 1330 EKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXX 1389
            +++                      E ++  +   Q I+ +N+     ++S+        
Sbjct: 1442 QQLKKIQHKNEQLTKSNEQFVSQLVEKENETESLGQKIILLNKSVTAYEQSNKKLKSEQQ 1501

Query: 1390 XXXXRVNDAEAKVLELTHQLEL--------KDSEIYQKTHEYTITLTQRNDEFENVRQQL 1441
                ++   E K  + +   +         K+ E+  K  E T  + Q    +++   +L
Sbjct: 1502 DLLDKIRVIENKSKKSSSPPKTQPINNNPSKEKELQNKIDEQTQLIKQ----YQHSLGKL 1557

Query: 1442 VEYEKRIEDLTYEKESELAILRLKMHENANH-------YETMQKESEIERVKLIEELNVK 1494
             E E+RI+    E      ++R     N  +       ++ +++E+   +VK+ E++ +K
Sbjct: 1558 NELEERIQLKNEENLILQQMIRQITSNNPKNEGVSAIAFDKIKQENSDLKVKM-EKIMLK 1616

Query: 1495 ----ITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRAS 1550
                I   ++   +V  L   L E+V  T  ++   +    E++   +E   L++ V  +
Sbjct: 1617 YKQIIVRYIAKFSKVVNLKAQLSEQVKVTESLKGKFKLLNEEVIKFEEENKVLKSCVTKN 1676

Query: 1551 SSKIQK 1556
              +I++
Sbjct: 1677 KKEIEE 1682



 Score =  155 bits (377), Expect = 7e-36
 Identities = 238/1164 (20%), Positives = 510/1164 (43%), Gaps = 108/1164 (9%)

Query: 506  KSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELH 565
            KS++       D ID   K+ + + S   L    +    D    +   N+++ +  + + 
Sbjct: 318  KSSDNPFELQKDMIDKTQKDDLLINSKWNLNEIPIPIYQDKVKDLQTLNQQLKQEKQTID 377

Query: 566  HLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFD 625
             L+QK   L++E  +L+       +G  ++ ++ +++I+   + E + K     ++++  
Sbjct: 378  DLNQK---LKQENESLK------KTGNQLQQEI-EQIIKQNKIKEVQNKEEFEAQNKRIK 427

Query: 626  LVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENL 685
             + E +  ++K D  +   +  SQ++S     + K+  LE++ D  ++  K   + ++  
Sbjct: 428  ELDERY-KKEKTDYQKQNESIKSQMESTISALQEKNKLLEQERDDANSKLKGSQIDMQQT 486

Query: 686  KLDKEQLYGTIKDLENDKEDIMN-KLQNY--IQENMDLTDKLEKMSAEKISELLAKIN-- 740
            K+   +   T+K    D++ I   K +N+  I E ++L  +++K ++++    ++K+N  
Sbjct: 487  KIKIGEELTTLKRQLTDEQQISKQKKENFEKIIEQLNLEIQMQKDASKEFENTISKLNAQ 546

Query: 741  -----HEEQSKIQTQFGIDAKIQER-DLYIENIESELSKYKSRICRLEESIAVMEDRRYS 794
                 +E Q +IQ+   +  KI+E      E+ E+E    K +I  LE S   + D+  +
Sbjct: 547  SEANKNESQVRIQSLEEVIKKIEEELKCMKESKETETKNLKQKITELETSNKDLGDQLKT 606

Query: 795  LERKADQLGSYLQEKQKAYSEYTIQEDELV---NRLAVLMDHDRVVEKQLLEIEHE--NK 849
               + + L   L + +   S    + DE +   N L +L+        Q L+ ++E  N+
Sbjct: 607  KTNETEDLNKKLNDLETENSNMRRELDETIKKSNSLEILIQEQSTRNSQELKDKNEIFNQ 666

Query: 850  ELQK----KNQI--LLEENQNLQISLSDMQQHYNALVE-KANRTDLAESESTKYQT---- 898
             +++    K +I  L EEN+ L+  L+   +      + K  +T L    S K  +    
Sbjct: 667  SIKEIARVKAEISSLHEENKLLKEQLATSHKELVETKQIKEEKTVLCVQLSEKLSSLQEQ 726

Query: 899  ------QLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEK 952
                  QL  LE +LK    + Q +I   K+EIE+LE   N Q+ SA   KK  N + ++
Sbjct: 727  FDVKSEQLDSLEISLK----QKQDIIDGLKEEIEELE---NEQLGSAENSKKEQNSQLQQ 779

Query: 953  NIEYVTQLEAQLQEYKNNIENLNMNV----EEL--------NKMN-LELIDKHVQKQQTQ 999
              E     + ++Q+ K+ I++L  N+    EE+        NK N +++ ++  +  + Q
Sbjct: 780  FKEQTDSFQNEIQQLKSQIQDLESNLKFKNEEIIKQDEIIKNKQNEIKINEEKAENVKHQ 839

Query: 1000 SPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLEN 1059
              +      N++ + N  LK ++EE     ++I  AQ S++ +  + E           N
Sbjct: 840  LEEKVLSLQNKLEESNNKLKTQEEESA---KEIEEAQSSFLKLRQELEVLKLSLEENENN 896

Query: 1060 MEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIE 1119
               E Q++ ++ +D     EE +  VREQ+ ++     T LT      K E   I    E
Sbjct: 897  HAYEKQQMEQREIDKNVLIEEYERKVREQNQEL-----TSLTAMQRKNKEE---IQRKDE 948

Query: 1120 PMSDDANNVDXXXXXXXXXXXXLKVQEEE--EFIQERSVLQEQSAKLNTELQECYTKIIQ 1177
             + +    +             LK Q ++  E+ Q+   L+E++     EL+    +I Q
Sbjct: 949  TILEKEKRIKQNQDKLSEVQNELKKQNQQLDEYKQQNQQLEERAINAEQELEREKMQIAQ 1008

Query: 1178 LETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAE 1237
             E     LT     N+EQ NQ+++ L+++  E +N ++   E  + +    ++   +I E
Sbjct: 1009 KEE-QISLTRKS--NEEQSNQIQNFLKEIQ-ELNNKVNEQVEYIAELEQLKEETNSQINE 1064

Query: 1238 LWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQ---EETNKIVTM--EQV 1292
            L ++   + E +  K   +L+ Q    +S+Y+QL + + S  Q   E +N  +T   E++
Sbjct: 1065 LNQEQKLKYE-EMHKQIEKLQKQCDFKDSQYQQLKEELSSQDQAKEERSNSTLTEKEERI 1123

Query: 1293 TSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDL 1352
             +L+    D E  L++ + +   ++ Q+   + +++  K+                   L
Sbjct: 1124 QNLEKSKFDLESSLQDKENECERLVQQVNNFQQQVK--KLKDDILTSTQETATLKKSIQL 1181

Query: 1353 RTENQSYKQMQEQSILNINEENAQLKKS-SXXXXXXXXXXXXRVNDAEAKVLELTHQLEL 1411
            +      KQ +   ++  ++E+   K                 +   E ++++L  Q++ 
Sbjct: 1182 KENEILVKQSEITKLMRESQESIDSKNQFKESLTRDIHNLNSNIQSKEREIIQLKSQVQT 1241

Query: 1412 KD---SEIYQKTHEYTITLTQRNDEFENVRQ-------QLVEYEKRIEDLTYEKESELAI 1461
             +   SE+ +  +++ I + Q   E    ++       +L E E+  +D   + E ++  
Sbjct: 1242 LNQELSELKESNNQFQIIIDQAESEKNEAQRTSLSNKAELDEIEQTYQDAQQKLEEKIRS 1301

Query: 1462 L--RLKMHENANHYETM---QKESEIE-RVKLIEELNVKITESVSLNKQVAELNKALEEE 1515
            L  +L++ E  +  E M   ++ S+++ ++ + EE + K+  S    K  A+  K++EE+
Sbjct: 1302 LQEKLQLLEQKSKEEMMMSLKENSDLKGKLNMFEEQH-KLKYSDYEKKHQAD-QKSIEEQ 1359

Query: 1516 VAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNT 1575
              + +   + +E  E+    +  ++ NL+  +++    I    +     +  +D Q++  
Sbjct: 1360 KKQISTQLSKIEELELSQAAITQQLENLKAELKSKEEVINGLNNQDQQNQHSKDGQIETL 1419

Query: 1576 MNKELLDAVPRAELDLAMYMLHQR 1599
              K L     + EL   +  L Q+
Sbjct: 1420 KQKLLSLESEKLELQNQVNELEQQ 1443



 Score =  145 bits (352), Expect = 8e-33
 Identities = 217/1007 (21%), Positives = 443/1007 (43%), Gaps = 85/1007 (8%)

Query: 144  VTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINE--KDQIIEAKN--KATTXXXXX 199
            ++ L      K   L  L++ +K  +  I  L+E+I E   +Q+  A+N  K        
Sbjct: 720  LSSLQEQFDVKSEQLDSLEISLKQKQDIIDGLKEEIEELENEQLGSAENSKKEQNSQLQQ 779

Query: 200  XXXXXXXXXXXXEDTKQQMTKMQENF------IAMEAEWKDEKQRLLKDIESKDVRIS-S 252
                        +  K Q+  ++ N       I  + E    KQ  +K  E K   +   
Sbjct: 780  FKEQTDSFQNEIQQLKSQIQDLESNLKFKNEEIIKQDEIIKNKQNEIKINEEKAENVKHQ 839

Query: 253  LEEA-----NKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEK 307
            LEE      NKL E +  ++  +  + A+E+E+              L K S+E +  E 
Sbjct: 840  LEEKVLSLQNKL-EESNNKLKTQEEESAKEIEEAQSSFLKLRQELEVL-KLSLEEN--EN 895

Query: 308  TEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGS 367
                EK  +E     E+ K + L+E    ++R+ N+EL +  A      + +    K  +
Sbjct: 896  NHAYEKQQME---QREIDKNV-LIEEYERKVREQNQELTSLTAMQRKNKEEIQR--KDET 949

Query: 368  PLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYV 427
             L   K  +    K+    ++L  +  NQ  D+   +N+  +LE    +  ++L  ++  
Sbjct: 950  ILEKEKRIKQNQDKLSEVQNELKKQ--NQQLDEYKQQNQ--QLEERAINAEQELEREKMQ 1005

Query: 428  ISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQ 487
            I++K+            +   I     E Q+       ++   N E V  IA++ EQLK+
Sbjct: 1006 IAQKEEQISLTRKSNEEQSNQIQNFLKEIQE-------LNNKVN-EQVEYIAEL-EQLKE 1056

Query: 488  ELNDEIKDVNVKDL---------IEKLKSA----EEQITQLNDEIDAANKNMIKVKSNHK 534
            E N +I ++N +           IEKL+      + Q  QL +E+ + ++   + +SN  
Sbjct: 1057 ETNSQINELNQEQKLKYEEMHKQIEKLQKQCDFKDSQYQQLKEELSSQDQAK-EERSNST 1115

Query: 535  L-----KLKQMQKT-IDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEE-KGNLQLHLVD 587
            L     +++ ++K+  D  S + D   E  RL +++++  Q+V +L+++   + Q     
Sbjct: 1116 LTEKEERIQNLEKSKFDLESSLQDKENECERLVQQVNNFQQQVKKLKDDILTSTQETATL 1175

Query: 588  YDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADI 647
              S ++ E+++  K  E+  L     ++I      K  L +++H L       E ++  +
Sbjct: 1176 KKSIQLKENEILVKQSEITKLMRESQESIDSKNQFKESLTRDIHNLNSNIQSKEREIIQL 1235

Query: 648  -SQLQS-DQVCSEIKSVHLEEQI--DALSASKKELALVIENLKLDKEQLYGTIKDLENDK 703
             SQ+Q+ +Q  SE+K  + + QI  D   + K E      + K + +++  T +D +   
Sbjct: 1236 KSQVQTLNQELSELKESNNQFQIIIDQAESEKNEAQRTSLSNKAELDEIEQTYQDAQQKL 1295

Query: 704  EDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKIN-HEEQSKIQTQFGIDAKIQERDL 762
            E+ +  LQ  +Q     + +   MS ++ S+L  K+N  EEQ K++     + K Q    
Sbjct: 1296 EEKIRSLQEKLQLLEQKSKEEMMMSLKENSDLKGKLNMFEEQHKLKYS-DYEKKHQADQK 1354

Query: 763  YIENIESELSKYKSRICRLEESIAV----MEDRRYSLERKADQLGSYLQEKQKAYSEYTI 818
             IE  + ++S   S+I  LE S A     +E+ +  L+ K + +     + Q+       
Sbjct: 1355 SIEEQKKQISTQLSKIEELELSQAAITQQLENLKAELKSKEEVINGLNNQDQQNQHSKDG 1414

Query: 819  QEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNA 878
            Q + L  +L  L      ++ Q+ E+E + K++Q KN+ L + N          +Q  + 
Sbjct: 1415 QIETLKQKLLSLESEKLELQNQVNELEQQLKKIQHKNEQLTKSN----------EQFVSQ 1464

Query: 879  LVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIES 938
            LVEK N T+    +       +   E + K++  E Q L+  K + IE+   + ++  ++
Sbjct: 1465 LVEKENETESLGQKIILLNKSVTAYEQSNKKLKSEQQDLL-DKIRVIENKSKKSSSPPKT 1523

Query: 939  -AIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLEL--IDKHVQK 995
              I +     ++ +  I+  TQL  Q Q     +  L   ++  N+ NL L  + + +  
Sbjct: 1524 QPINNNPSKEKELQNKIDEQTQLIKQYQHSLGKLNELEERIQLKNEENLILQQMIRQITS 1583

Query: 996  QQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTT 1055
               ++   +    ++I + N+ LK K E+I+   ++I    ++  S V + +++L++   
Sbjct: 1584 NNPKNEGVSAIAFDKIKQENSDLKVKMEKIMLKYKQIIVRYIAKFSKVVNLKAQLSEQVK 1643

Query: 1056 KLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTF 1102
              E+++ + + ++++++  ++ N+ L+  V +   +I+E K+ +L +
Sbjct: 1644 VTESLKGKFKLLNEEVIKFEEENKVLKSCVTKNKKEIEE-KDQQLEY 1689



 Score =  134 bits (323), Expect = 3e-29
 Identities = 190/979 (19%), Positives = 407/979 (41%), Gaps = 72/979 (7%)

Query: 632  ILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQ 691
            I   KY ++   +A    +  D +CS+      E Q D +  ++K+  L+     L++  
Sbjct: 292  ISTSKYTQLIKYIATFLFINRDSICSKSSDNPFELQKDMIDKTQKDDLLINSKWNLNEIP 351

Query: 692  L---YGTIKDLENDKEDIMNKLQNYIQENMDL---TDKLEKMSAEKISELLAKINHEEQS 745
            +      +KDL+   + +  + Q     N  L    + L+K   +   E+   I   +  
Sbjct: 352  IPIYQDKVKDLQTLNQQLKQEKQTIDDLNQKLKQENESLKKTGNQLQQEIEQIIKQNKIK 411

Query: 746  KIQTQFGIDA---KIQERDLYIENIESELSKYKSRI-CRLEESIAVMEDRRYSLERKADQ 801
            ++Q +   +A   +I+E D   +  +++  K    I  ++E +I+ ++++   LE++ D 
Sbjct: 412  EVQNKEEFEAQNKRIKELDERYKKEKTDYQKQNESIKSQMESTISALQEKNKLLEQERDD 471

Query: 802  LGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEE 861
              S L+  Q    +  I+  E +  L   +  ++ + KQ           +K+N   + E
Sbjct: 472  ANSKLKGSQIDMQQTKIKIGEELTTLKRQLTDEQQISKQ-----------KKENFEKIIE 520

Query: 862  NQNLQISL-SDMQQHYNALVEKANRTDLAESESTKYQTQLR--DLESNLKRITHEHQTLI 918
              NL+I +  D  + +   + K N    A+SE+ K ++Q+R   LE  +K+I  E + + 
Sbjct: 521  QLNLEIQMQKDASKEFENTISKLN----AQSEANKNESQVRIQSLEEVIKKIEEELKCMK 576

Query: 919  VQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNV 978
              K+ E ++L+ +  T++E++ +D   L ++ +        L  +L + +    N+   +
Sbjct: 577  ESKETETKNLKQKI-TELETSNKD---LGDQLKTKTNETEDLNKKLNDLETENSNMRREL 632

Query: 979  EE-LNKMN-LE-LIDKHVQKQQTQSPDYTE---QYINEINKLNALLKQKDEEIIALNQKI 1032
            +E + K N LE LI +   +   +  D  E   Q I EI ++ A +    EE   L +++
Sbjct: 633  DETIKKSNSLEILIQEQSTRNSQELKDKNEIFNQSIKEIARVKAEISSLHEENKLLKEQL 692

Query: 1033 NNAQVSYMSMVSDYESK---LAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQD 1089
              +    +      E K     Q + KL +++E+    S+QL   +   ++ Q ++    
Sbjct: 693  ATSHKELVETKQIKEEKTVLCVQLSEKLSSLQEQFDVKSEQLDSLEISLKQKQDIIDGLK 752

Query: 1090 DQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEE 1149
            ++I+EL+  +L    N  K +   +    E      N +             LK + EE 
Sbjct: 753  EEIEELENEQLGSAENSKKEQNSQLQQFKEQTDSFQNEIQQLKSQIQDLESNLKFKNEEI 812

Query: 1150 FIQERSVLQEQS-AKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNT 1208
              Q+  +  +Q+  K+N E  E     ++ + L+ +        +E  N+LK++ E+   
Sbjct: 813  IKQDEIIKNKQNEIKINEEKAENVKHQLEEKVLSLQNK-----LEESNNKLKTQEEESAK 867

Query: 1209 ENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKY 1268
            E +   S+  +LR  +    +     + E    H A  +   ++ E +  V +  +E K 
Sbjct: 868  EIEEAQSSFLKLRQEL----EVLKLSLEENENNH-AYEKQQMEQREIDKNVLIEEYERKV 922

Query: 1269 -EQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEI 1327
             EQ  +    +  +  NK    E++      + +KE+ ++  Q+K ++V N+++    ++
Sbjct: 923  REQNQELTSLTAMQRKNK----EEIQRKDETILEKEKRIKQNQDKLSEVQNELKKQNQQL 978

Query: 1328 EDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXX 1387
            ++ K                   +L  E     Q +EQ  L   + N +           
Sbjct: 979  DEYK----QQNQQLEERAINAEQELEREKMQIAQKEEQISLT-RKSNEEQSNQIQNFLKE 1033

Query: 1388 XXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQL----VE 1443
                  +VN+    + EL    E  +S+I +   E  +   + + + E +++Q      +
Sbjct: 1034 IQELNNKVNEQVEYIAELEQLKEETNSQINELNQEQKLKYEEMHKQIEKLQKQCDFKDSQ 1093

Query: 1444 YEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELN--VKITESV-S 1500
            Y++  E+L+ + +++       + E     + ++K        L ++ N   ++ + V +
Sbjct: 1094 YQQLKEELSSQDQAKEERSNSTLTEKEERIQNLEKSKFDLESSLQDKENECERLVQQVNN 1153

Query: 1501 LNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSF 1560
              +QV +L   +     +T  ++ +++ +E EI+    EIT L   +R S   I     F
Sbjct: 1154 FQQQVKKLKDDILTSTQETATLKKSIQLKENEILVKQSEITKL---MRESQESIDSKNQF 1210

Query: 1561 ASDTKQGRDEQLDNTMNKE 1579
                 +       N  +KE
Sbjct: 1211 KESLTRDIHNLNSNIQSKE 1229



 Score =  134 bits (323), Expect = 3e-29
 Identities = 233/1204 (19%), Positives = 517/1204 (42%), Gaps = 120/1204 (9%)

Query: 152  KEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXX 211
            + K+     L+ K+  +ET+  DL +++  K    E  NK                    
Sbjct: 577  ESKETETKNLKQKITELETSNKDLGDQLKTKTNETEDLNKKLNDLETENSNMRRELDETI 636

Query: 212  EDTKQQMTKMQENFIAMEAEWKDEKQ---RLLKDIESKDVRISSLEEANKLLEAARFEIS 268
            + +      +QE       E KD+ +   + +K+I      ISSL E NKLL+    +++
Sbjct: 637  KKSNSLEILIQEQSTRNSQELKDKNEIFNQSIKEIARVKAEISSLHEENKLLKE---QLA 693

Query: 269  LEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKI 328
              H +L +  +               L+  S++   + K+  E+  SLEI+    L +K 
Sbjct: 694  TSHKELVETKQIKEEKTVLCVQLSEKLS--SLQEQFDVKS--EQLDSLEIS----LKQKQ 745

Query: 329  ELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQ 388
            ++++ L  +I    +ELEN+       SK   + S+         S +N   ++KS    
Sbjct: 746  DIIDGLKEEI----EELENEQLGSAENSKKEQN-SQLQQFKEQTDSFQNEIQQLKSQIQD 800

Query: 389  LSS-------ETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXX 441
            L S       E + QD   K  +NEI   E   +++   L +K  V+S ++         
Sbjct: 801  LESNLKFKNEEIIKQDEIIKNKQNEIKINEEKAENVKHQLEEK--VLSLQNKLEESNNKL 858

Query: 442  XXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDL 501
               ++    +++      ++    + V   + + NE     E+ + E  +  K+V +++ 
Sbjct: 859  KTQEEESAKEIEEAQSSFLKLRQELEVLKLSLEENENNHAYEKQQMEQREIDKNVLIEEY 918

Query: 502  IEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLT 561
              K++   +++T L        KN  +++   +  L++ ++   N  K+S+   E+ +  
Sbjct: 919  ERKVREQNQELTSLT---AMQRKNKEEIQRKDETILEKEKRIKQNQDKLSEVQNELKKQN 975

Query: 562  EELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLES 621
            ++L    Q+  +LEE   N +  L         E +  +   + E ++ TR K+     +
Sbjct: 976  QQLDEYKQQNQQLEERAINAEQEL---------EREKMQIAQKEEQISLTR-KSNEEQSN 1025

Query: 622  QKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALV 681
            Q  + ++E+  L  K +E  + +A++ QL+ ++  S+I  ++ E+               
Sbjct: 1026 QIQNFLKEIQELNNKVNEQVEYIAELEQLK-EETNSQINELNQEQ--------------- 1069

Query: 682  IENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKL-EKMSAEKISELLAKIN 740
                KL  E+++  I+ L+  + D  +     ++E +   D+  E+ S   ++E   +I 
Sbjct: 1070 ----KLKYEEMHKQIEKLQK-QCDFKDSQYQQLKEELSSQDQAKEERSNSTLTEKEERIQ 1124

Query: 741  HEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLER--- 797
            + E+SK    F +++ +Q+++   E +  +++ ++ ++ +L++ I        +L++   
Sbjct: 1125 NLEKSK----FDLESSLQDKENECERLVQQVNNFQQQVKKLKDDILTSTQETATLKKSIQ 1180

Query: 798  --------KADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENK 849
                    K  ++   ++E Q++       ++ L   +  L  + +  E+++++++ + +
Sbjct: 1181 LKENEILVKQSEITKLMRESQESIDSKNQFKESLTRDIHNLNSNIQSKEREIIQLKSQVQ 1240

Query: 850  ELQKKNQILLEENQNLQISLSDMQQHYNAL--VEKANRTDLAESESTKYQTQLRDLESNL 907
             L ++   L E N   QI +   +   N       +N+ +L E E T YQ   + LE  +
Sbjct: 1241 TLNQELSELKESNNQFQIIIDQAESEKNEAQRTSLSNKAELDEIEQT-YQDAQQKLEEKI 1299

Query: 908  KRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQ-LQE 966
            + +  + Q L+ QK KE   + ++ N+ ++  +   +  ++    + E   Q + + ++E
Sbjct: 1300 RSLQEKLQ-LLEQKSKEEMMMSLKENSDLKGKLNMFEEQHKLKYSDYEKKHQADQKSIEE 1358

Query: 967  YKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLK-QKDEEI 1025
             K  I      +EEL +++   I + ++  + +     E+ IN +N  +   +  KD +I
Sbjct: 1359 QKKQISTQLSKIEEL-ELSQAAITQQLENLKAELKS-KEEVINGLNNQDQQNQHSKDGQI 1416

Query: 1026 IALNQK---INNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEEL- 1081
              L QK   + + ++   + V++ E +L +   K E + +  ++   QL++ +   E L 
Sbjct: 1417 ETLKQKLLSLESEKLELQNQVNELEQQLKKIQHKNEQLTKSNEQFVSQLVEKENETESLG 1476

Query: 1082 -QILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXX 1140
             +I++  +     E    KL  E      +  +I +  +  S                  
Sbjct: 1477 QKIILLNKSVTAYEQSNKKLKSEQQDLLDKIRVIENKSKKSSSPPKTQPINNNPSKEKEL 1536

Query: 1141 XLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLK 1200
              K+ E+ + I++    Q    KLN EL+E      +++  N E    +++ Q+ I Q+ 
Sbjct: 1537 QNKIDEQTQLIKQ---YQHSLGKLN-ELEE------RIQLKNEE----NLILQQMIRQIT 1582

Query: 1201 SKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQ 1260
            S     N +N+ + +   +     +S +  +  +I   +KQ + +  A F K  + L+ Q
Sbjct: 1583 SN----NPKNEGVSAIAFDKIKQENSDLKVKMEKIMLKYKQIIVRYIAKFSKVVN-LKAQ 1637

Query: 1261 LS-------AFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKY 1313
            LS       + + K++ L + V     EE NK++    VT  + ++++K++ L  L +++
Sbjct: 1638 LSEQVKVTESLKGKFKLLNEEVIKF--EEENKVL-KSCVTKNKKEIEEKDQQLEYLSQRH 1694

Query: 1314 ADVI 1317
               I
Sbjct: 1695 QQQI 1698



 Score = 92.7 bits (220), Expect = 8e-17
 Identities = 196/1021 (19%), Positives = 419/1021 (41%), Gaps = 101/1021 (9%)

Query: 50   RQIKFERAQKCLENAALVSKRIKEHRKATAELLGRPFVPGISESLANTLKQKEILMEKIK 109
            +QIK E+   C++ +  +S  ++E     +E L         +SL  +LKQK+ +++ +K
Sbjct: 703  KQIKEEKTVLCVQLSEKLSS-LQEQFDVKSEQL---------DSLEISLKQKQDIIDGLK 752

Query: 110  QYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNALSVLQVKMKIME 169
            +  E  +                       Q        N I++  + +  L+  +K   
Sbjct: 753  EEIEELENEQLGSAENSKKEQNSQLQQFKEQTDS---FQNEIQQLKSQIQDLESNLKFKN 809

Query: 170  TTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAME 229
              I+   E I  K   I+   +                    E++  ++ K QE   A E
Sbjct: 810  EEIIKQDEIIKNKQNEIKINEEKAENVKHQLEEKVLSLQNKLEESNNKL-KTQEEESAKE 868

Query: 230  AEWKDEKQRLLKDIESKDVRISSLEEA--NKLLEAARFEI-SLEHSKLAQELEQXXXXXX 286
             E  + +   LK  +  +V   SLEE   N   E  + E   ++ + L +E E+      
Sbjct: 869  IE--EAQSSFLKLRQELEVLKLSLEENENNHAYEKQQMEQREIDKNVLIEEYERKVREQN 926

Query: 287  XXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQI---RQTNK 343
                    + +++ E    +   I EK      N  +L++    L+  N Q+   +Q N+
Sbjct: 927  QELTSLTAMQRKNKEEIQRKDETILEKEKRIKQNQDKLSEVQNELKKQNQQLDEYKQQNQ 986

Query: 344  ELENKL--ATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKK 401
            +LE +   A    E + +    K+    ++RKS    ++++++   ++  + LN   +++
Sbjct: 987  QLEERAINAEQELEREKMQIAQKEEQISLTRKSNEEQSNQIQNFLKEI--QELNNKVNEQ 1044

Query: 402  INKNEIAKLEMVIQSLNKDL----VDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLE-- 455
            +    IA+LE + +  N  +     +++    E              KD+   QL+ E  
Sbjct: 1045 VEY--IAELEQLKEETNSQINELNQEQKLKYEEMHKQIEKLQKQCDFKDSQYQQLKEELS 1102

Query: 456  -HQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQ 514
               Q  E  S   +    E +  + K +  L+  L D  K+   + L++++ + ++Q+ +
Sbjct: 1103 SQDQAKEERSNSTLTEKEERIQNLEKSKFDLESSLQD--KENECERLVQQVNNFQQQVKK 1160

Query: 515  LNDEI------DAANKNMIKVKSNHKLK--------LKQMQKTIDNFSKVSDS------- 553
            L D+I       A  K  I++K N  L         +++ Q++ID+ ++  +S       
Sbjct: 1161 LKDDILTSTQETATLKKSIQLKENEILVKQSEITKLMRESQESIDSKNQFKESLTRDIHN 1220

Query: 554  --------NKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRM-IESDVYKKMIE 604
                     +EI++L  ++  L+Q+++EL+E     Q+ +   +S +   +        E
Sbjct: 1221 LNSNIQSKEREIIQLKSQVQTLNQELSELKESNNQFQIIIDQAESEKNEAQRTSLSNKAE 1280

Query: 605  MENLAETRLKAISLLESQKFDLVQELHILQQKY-DEVEDKLADISQLQS------DQVCS 657
            ++ + +T   A   LE +   L ++L +L+QK  +E+   L + S L+       +Q   
Sbjct: 1281 LDEIEQTYQDAQQKLEEKIRSLQEKLQLLEQKSKEEMMMSLKENSDLKGKLNMFEEQHKL 1340

Query: 658  EIKSVHLEEQID--ALSASKKELALV---IENLKLDKEQLYGTIKDLEND---KEDIMNK 709
            +      + Q D  ++   KK+++     IE L+L +  +   +++L+ +   KE+++N 
Sbjct: 1341 KYSDYEKKHQADQKSIEEQKKQISTQLSKIEELELSQAAITQQLENLKAELKSKEEVING 1400

Query: 710  LQNYIQENMDLTD--------KLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERD 761
            L N  Q+N    D        KL  + +EK+ EL  ++N  EQ   + Q   +   +  +
Sbjct: 1401 LNNQDQQNQHSKDGQIETLKQKLLSLESEKL-ELQNQVNELEQQLKKIQHKNEQLTKSNE 1459

Query: 762  LYIENI---ESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQ--EKQKAYSEY 816
             ++  +   E+E      +I  L +S+   E     L+ +   L   ++  E +   S  
Sbjct: 1460 QFVSQLVEKENETESLGQKIILLNKSVTAYEQSNKKLKSEQQDLLDKIRVIENKSKKSSS 1519

Query: 817  TIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHY 876
              +   + N  +   +    +++Q   I+     L K N+  LEE   L+   + + Q  
Sbjct: 1520 PPKTQPINNNPSKEKELQNKIDEQTQLIKQYQHSLGKLNE--LEERIQLKNEENLILQQM 1577

Query: 877  NALVEKANRTDLAESEST--KYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNT 934
               +   N  +   S     K + +  DL+  +++I  +++ +IV+   +   + +    
Sbjct: 1578 IRQITSNNPKNEGVSAIAFDKIKQENSDLKVKMEKIMLKYKQIIVRYIAKFSKV-VNLKA 1636

Query: 935  QIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQ 994
            Q+   ++  + L  K++   E V + E + +  K+ +      +EE ++    L  +H Q
Sbjct: 1637 QLSEQVKVTESLKGKFKLLNEEVIKFEEENKVLKSCVTKNKKEIEEKDQQLEYLSQRHQQ 1696

Query: 995  K 995
            +
Sbjct: 1697 Q 1697



 Score = 49.6 bits (113), Expect = 7e-04
 Identities = 84/434 (19%), Positives = 186/434 (42%), Gaps = 29/434 (6%)

Query: 168  METTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIA 227
            +E T  D Q+K+ EK + ++ K +                     D K ++   +E    
Sbjct: 1284 IEQTYQDAQQKLEEKIRSLQEKLQLLEQKSKEEMMMSLKENS---DLKGKLNMFEEQHKL 1340

Query: 228  MEAEWKDEKQRLLKDIESKDVRISS-LEEANKL-LEAARFEISLEHSKLAQELEQXXXXX 285
              ++++ + Q   K IE +  +IS+ L +  +L L  A     LE+ K   + ++     
Sbjct: 1341 KYSDYEKKHQADQKSIEEQKKQISTQLSKIEELELSQAAITQQLENLKAELKSKEEVING 1400

Query: 286  XXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIAN-MTELTKKIELLEHLNCQIRQTNKE 344
                      +K     + ++K    E   LE+ N + EL ++++ ++H N Q+ ++N++
Sbjct: 1401 LNNQDQQNQHSKDGQIETLKQKLLSLESEKLELQNQVNELEQQLKKIQHKNEQLTKSNEQ 1460

Query: 345  LENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINK 404
              ++L     E++++       +  ++     N   K+KS    L  + +    +K    
Sbjct: 1461 FVSQLVEKENETESLGQKIILLNKSVTAYEQSN--KKLKSEQQDLLDK-IRVIENKSKKS 1517

Query: 405  NEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGK-DTLIAQLQLEHQQHMEGP 463
            +   K + +  + +K+   +  +  ++ T          GK + L  ++QL++++++   
Sbjct: 1518 SSPPKTQPINNNPSKEKELQNKI--DEQTQLIKQYQHSLGKLNELEERIQLKNEENLILQ 1575

Query: 464  SLIHVGTNTEDVNE--IAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEID- 520
             +I   T+    NE   A   +++KQE N ++K    K +++  +     I + +  ++ 
Sbjct: 1576 QMIRQITSNNPKNEGVSAIAFDKIKQE-NSDLKVKMEKIMLKYKQIIVRYIAKFSKVVNL 1634

Query: 521  -AANKNMIKVKSNHKLKLKQMQKTIDNFSK--------VSDSNKEIVRLTEELHHLSQK- 570
             A     +KV  + K K K + + +  F +        V+ + KEI    ++L +LSQ+ 
Sbjct: 1635 KAQLSEQVKVTESLKGKFKLLNEEVIKFEEENKVLKSCVTKNKKEIEEKDQQLEYLSQRH 1694

Query: 571  ---VAELEEEKGNL 581
               +  L EE G+L
Sbjct: 1695 QQQIILLTEENGDL 1708


>UniRef50_UPI000065DFDD Cluster: Homolog of Homo sapiens "Centromeric
            protein E; n=1; Takifugu rubripes|Rep: Homolog of Homo
            sapiens "Centromeric protein E - Takifugu rubripes
          Length = 2139

 Score =  155 bits (377), Expect = 7e-36
 Identities = 269/1344 (20%), Positives = 552/1344 (41%), Gaps = 105/1344 (7%)

Query: 297  KQSIEPSCEEKTEIEEK--GSLEIAN------MTELTKKIELLEHLNCQIRQTNKELENK 348
            KQ ++   E++ E+ E+   SL+ AN        EL +  EL+  + C   +  +EL  +
Sbjct: 787  KQQLKAELEDRMELIEQLQTSLQAANDQRIQLEDELQRNSELIIEIQCHFGRLEEELLEQ 846

Query: 349  LATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIA 408
               M    K      +K S L  +++  +   +++S  S+  +  L +D+       E  
Sbjct: 847  KQKMADNMKLWE---QKESDLEQQRT--SLTEQLESAQSERDALMLEKDSRTHTYTEEKE 901

Query: 409  KLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHV 468
            +L   + +L+KD  + + ++                +  ++ QLQ    QH+E       
Sbjct: 902  ELHRNLVTLSKDREELQEMVEMLRQEKQQLRTELEDRMEMLQQLQ----QHLE------- 950

Query: 469  GTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIK 528
             ++ E+VN       QLK +L + ++ +    L E+L + + +   L  E DA+  N ++
Sbjct: 951  -SSKEEVN-------QLKSDLEENVELIQC--LKEELLNIKAERDALWSEKDASCSNSLQ 1000

Query: 529  VKSNHKLKLKQMQKTIDNFSK---VSDSNKE-----IVRLTEELHHLSQKVAELEEEKGN 580
             KS+ + +L  + +  +           +KE     ++ LTEE   L   +  L +EK  
Sbjct: 1001 EKSDLQSRLTSLTEEKEELQSRLVALGEDKEALQNSLISLTEEKEELQSHLTSLSKEKEE 1060

Query: 581  LQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEV 640
            LQ  L+        + DV   ++ +    E     +  L   K  L   +  L ++ +E+
Sbjct: 1061 LQSRLMALGE---YKEDVKSSLMSLTEEKEALQSRLMALGEDKEALQSSVQSLSKEKEEL 1117

Query: 641  EDKLADISQLQSDQVCSEIKSVH-----LEEQIDALSASKKELALVIENLKLDKEQLYGT 695
            + +L  + + ++D V S + S+      L+ ++ AL   K+ L   +++L  +KE+L   
Sbjct: 1118 QSRLMALGEDKAD-VKSSLMSLTEEKEALQSRLMALGEDKEALQSSVQSLSKEKEELQSR 1176

Query: 696  IKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDA 755
            +  L  DKED+ +   +  +E  +L   L  +  E +   L  +  E+++       +  
Sbjct: 1177 LMALGEDKEDVKSSFMSLTEEKEELQSHLTALKKEDLQSSLMSLTEEKEALQSHLMALGE 1236

Query: 756  KIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYL----QEKQK 811
            + +     ++++  E  + +SR+  L E  A ++    SL  + ++L S+L    +EK+ 
Sbjct: 1237 EKEALQSSVQSLSKEKEELQSRLMALGEDKADVKSSFMSLTEEKEELQSHLTSLSKEKED 1296

Query: 812  AYSEYTI---QEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQIS 868
             +S       +++EL +RL  L +    +++ LL +  E +ELQ     L +E + L+  
Sbjct: 1297 LHSHLASLVEEKEELQSRLVSLGEEKEDLQRSLLSLTEEKEELQSHLTSLSKEKEELKSR 1356

Query: 869  LSDMQQH----YNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKE 924
            L  + +      N+L+  +   +  +S  T    +  + +  L+ +  E Q L  + ++ 
Sbjct: 1357 LESLCEEKEALQNSLMSLSGEKEELQSNLTSLSEEREEFQKILEMLRQEKQHLQAEMQER 1416

Query: 925  IEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKM 984
            ++ L+ E +T +   + D K   +      E      +Q QE ++ + +L    EE++++
Sbjct: 1417 VDSLQTEIST-VNKKMDDIKTERDGLMSEKEASCWASSQEQELQSRLTSLREEKEEMSEL 1475

Query: 985  NLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVS 1044
             LE++ +  Q+ +T+          E+  L   L Q   E    N+++ N   S      
Sbjct: 1476 -LEMVKREEQQLRTEMKCKLVALQTEVRTLTEKL-QGISETSQENEEMQNRLASLGIEKE 1533

Query: 1045 DYESKLAQFTTKLENMEEEMQRVSKQLLDS-KQHNEELQILVR-----EQDDQIKELKET 1098
            + +    Q  T     E E+Q++  +   S     ++L  L++     +  D  K+++E 
Sbjct: 1534 ELQISALQQETDGGEREAELQQLLVEANSSIAALQDQLDRLIKNPIMSQLQDSNKQIQEF 1593

Query: 1099 KLTFEMNIPKTEGMIISSTIEPMSDDANN-----VDXXXXXXXXXXXXLKVQEEEEFIQE 1153
              TF+  I     M +  T++  +   NN     V             L++Q  +  +  
Sbjct: 1594 LGTFQQFIEACSRMKV--TVQNEAQRVNNPCPKFVPKSSRKSYSTVCQLRIQTLQCLLNT 1651

Query: 1154 RSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNL 1213
               LQEQ A++   L E   K  +L T   +     ++ ++Q      + E  N      
Sbjct: 1652 MEYLQEQ-AQVYRNLFEDLLKKDRL-TFEEKCLQDVLLCRDQTYSFSVRDEDFNKLWRYR 1709

Query: 1214 LSTVAELRSSISSAVDQRGFEIAELW-KQHLAQREADFQKTEHE-LRVQLSAFESKYEQL 1271
            L+ + + R+     + Q  +E  +LW        E   +  EHE  + QL A +   +Q+
Sbjct: 1710 LTELLDKRNVYMKKM-QTIWE--KLWANMSYFTNELSAEVREHESFKEQLQA-KVGLDQI 1765

Query: 1272 L--DSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIED 1329
            L  +  + ST  ET  I     +  L+ +  +  E L+ LQ +    + +    R  +  
Sbjct: 1766 LGGELQRRSTMVETRNI----HLQQLREENSNMCEELKCLQVQNDSELREERSRRCSMLQ 1821

Query: 1330 EKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXX 1389
            E+V                  D      + KQ  E+  L ++   +  K+++        
Sbjct: 1822 EEVQGAAFDTQQLLLKLQQAEDKVRLMNAEKQQLEKDQLQVHGRLSSHKEATQLLQTELQ 1881

Query: 1390 XXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITL-TQRNDEFENVRQQLVEYEK-- 1446
                +V D +  +  L +Q  LK++++Y+     T  + T       +V      + K  
Sbjct: 1882 DSRAQVQDQDNTIQTLRNQ--LKEAQVYRSVLIITAAVGTFEGFCLTDVSSAEKCFAKIQ 1939

Query: 1447 RIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVA 1506
            + + L   KE  +  L+  + ++  H E    + E    +L     + I  S++  K  A
Sbjct: 1940 KFKVLLNTKEESVRKLKELLRKSQQHGEESILQGEDLHARLTNPKGLNIRTSIAAEK--A 1997

Query: 1507 ELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQ 1566
            +L + +++   K +E+++ +  Q  E+         L+     +  ++ K  S  + TK+
Sbjct: 1998 KLEEEVQQLQLKISELESQVSCQAAELSKWKSRAIKLK---AKTKPELDKPGSPCTPTKR 2054

Query: 1567 GRDEQLDNTMNKELLDAVPRAELD 1590
            G       T +  LL +  R  LD
Sbjct: 2055 G---LCSTTESSHLLSSPKRKVLD 2075



 Score =  140 bits (339), Expect = 3e-31
 Identities = 261/1378 (18%), Positives = 571/1378 (41%), Gaps = 107/1378 (7%)

Query: 216  QQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSL----EEANKLLEAARFEISLEH 271
            +Q+ + ++  +++E E  +E Q+LLKD+E K V   +     EE +K L+    E++ E 
Sbjct: 587  KQLEQSEQQKLSLE-EKINEMQQLLKDLEEKLVDSENSRETEEEISKELQEQLNELNREL 645

Query: 272  SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELL 331
                 E EQ              L  +  +   E +  +E+    + A +      I+  
Sbjct: 646  QCERAEKEQNVHSSTETERLISSLTAERDQFRAELQDNVEKAAEAQ-AVLHSFQDDIQHH 704

Query: 332  EHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSS 391
               N  + + +++ ++ +  +  E + V     +     +R+SG     +++     L++
Sbjct: 705  RQKNADLMKLSEQKDSDIENLSRELQRVCDELAE-----ARRSGEE-ERQLQPVIDSLTA 758

Query: 392  ETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQ 451
            E   Q     +N+ E  +L+ +I  L ++    +  + ++              +    Q
Sbjct: 759  EQDQQGRFAILNR-EKEELQEIIDVLRQEKQQLKAELEDRMELIEQLQTSLQAANDQRIQ 817

Query: 452  LQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQ 511
            L+ E Q++ E   +I +  +   + E  ++ EQ KQ++ D     N+K   +K    E+Q
Sbjct: 818  LEDELQRNSE--LIIEIQCHFGRLEE--ELLEQ-KQKMAD-----NMKLWEQKESDLEQQ 867

Query: 512  ITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKV 571
             T L +++++A            L L++  +T     +  + ++ +V L+++   L + V
Sbjct: 868  RTSLTEQLESAQ------SERDALMLEKDSRTHTYTEEKEELHRNLVTLSKDREELQEMV 921

Query: 572  AELEEEKGNLQLHLVD-YDSGRMIESDVYKKMIEMENL---AETRLKAISLLESQKFDLV 627
              L +EK  L+  L D  +  + ++  +     E+  L    E  ++ I  L+ +  ++ 
Sbjct: 922  EMLRQEKQQLRTELEDRMEMLQQLQQHLESSKEEVNQLKSDLEENVELIQCLKEELLNIK 981

Query: 628  QELHILQQKYD-EVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLK 686
             E   L  + D    + L + S LQS       +   L+ ++ AL   K+ L   + +L 
Sbjct: 982  AERDALWSEKDASCSNSLQEKSDLQSRLTSLTEEKEELQSRLVALGEDKEALQNSLISLT 1041

Query: 687  LDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSK 746
             +KE+L   +  L  +KE++ ++L    +   D+   L  ++ EK   L +++    + K
Sbjct: 1042 EEKEELQSHLTSLSKEKEELQSRLMALGEYKEDVKSSLMSLTEEK-EALQSRLMALGEDK 1100

Query: 747  IQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYL 806
               Q  + +  +E+    E ++S L         ++ S+  + + + +L+ +   LG   
Sbjct: 1101 EALQSSVQSLSKEK----EELQSRLMALGEDKADVKSSLMSLTEEKEALQSRLMALGEDK 1156

Query: 807  QEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQ 866
            +  Q +    + +++EL +RL  L +    V+   + +  E +ELQ     L +E  +LQ
Sbjct: 1157 EALQSSVQSLSKEKEELQSRLMALGEDKEDVKSSFMSLTEEKEELQSHLTALKKE--DLQ 1214

Query: 867  ISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIE 926
             SL  + +   AL  +++   L E E    Q+ ++ L S  K         + + K +++
Sbjct: 1215 SSLMSLTEEKEAL--QSHLMALGE-EKEALQSSVQSL-SKEKEELQSRLMALGEDKADVK 1270

Query: 927  DLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNL 986
               +    + E        L+++ E    ++  L  + +E ++ + +L    E+L +  L
Sbjct: 1271 SSFMSLTEEKEELQSHLTSLSKEKEDLHSHLASLVEEKEELQSRLVSLGEEKEDLQRSLL 1330

Query: 987  ELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDY 1046
             L +   +K++ QS      ++  ++K    LK + E +    + + N+ +S      + 
Sbjct: 1331 SLTE---EKEELQS------HLTSLSKEKEELKSRLESLCEEKEALQNSLMSLSGEKEEL 1381

Query: 1047 ESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNI 1106
            +S L    T L    EE Q++ + L   KQH   LQ  ++E+ D + + + + +  +M+ 
Sbjct: 1382 QSNL----TSLSEEREEFQKILEMLRQEKQH---LQAEMQERVDSL-QTEISTVNKKMDD 1433

Query: 1107 PKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNT 1166
             KTE   + S  E  S  A++ +               +E+EE  +   +++ +  +L T
Sbjct: 1434 IKTERDGLMSEKE-ASCWASSQEQELQSRLTSLR----EEKEEMSELLEMVKREEQQLRT 1488

Query: 1167 ELQECYTKIIQLE--TLNTELTGHDVVNQEQINQLKSKLEQLNTENDNL-LSTV------ 1217
            E+ +C    +Q E  TL  +L G    +QE   +++++L  L  E + L +S +      
Sbjct: 1489 EM-KCKLVALQTEVRTLTEKLQGISETSQEN-EEMQNRLASLGIEKEELQISALQQETDG 1546

Query: 1218 ----AELRSSI---SSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQ 1270
                AEL+  +   +S++     ++  L K  +  +  D  K   E       F     +
Sbjct: 1547 GEREAELQQLLVEANSSIAALQDQLDRLIKNPIMSQLQDSNKQIQEFLGTFQQFIEACSR 1606

Query: 1271 LLDSVQSSTQEETN---KIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEI 1327
            +  +VQ+  Q   N   K V      S     Q + + L+ L      +  Q ++ R+  
Sbjct: 1607 MKVTVQNEAQRVNNPCPKFVPKSSRKSYSTVCQLRIQTLQCLLNTMEYLQEQAQVYRNLF 1666

Query: 1328 ED----EKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILN-INEENAQLKKSSX 1382
            ED    +++ F                     ++ + ++    +   +++ N  +KK   
Sbjct: 1667 EDLLKKDRLTFEEKCLQDVLLCRDQTYSFSVRDEDFNKLWRYRLTELLDKRNVYMKKMQT 1726

Query: 1383 XXXXXXXXXXXRVNDAEAKVLE---LTHQLELK---DSEIYQKTHEYTITLTQRNDEFEN 1436
                         N+  A+V E      QL+ K   D  +  +    +  +  RN   + 
Sbjct: 1727 IWEKLWANMSYFTNELSAEVREHESFKEQLQAKVGLDQILGGELQRRSTMVETRNIHLQQ 1786

Query: 1437 VRQQLVEYEKRIEDLTYEKESELAILR------LKMHENANHYETMQKESEIERVKLIEE 1490
            +R++     + ++ L  + +SEL   R      L+       ++T Q   ++++ +  ++
Sbjct: 1787 LREENSNMCEELKCLQVQNDSELREERSRRCSMLQEEVQGAAFDTQQLLLKLQQAE--DK 1844

Query: 1491 LNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVR 1548
            + +   E   L K   +++  L      T  +QT L++   ++   ++ I  L+N ++
Sbjct: 1845 VRLMNAEKQQLEKDQLQVHGRLSSHKEATQLLQTELQDSRAQVQDQDNTIQTLRNQLK 1902



 Score =  122 bits (294), Expect = 8e-26
 Identities = 248/1327 (18%), Positives = 537/1327 (40%), Gaps = 91/1327 (6%)

Query: 249  RISSLEEANKLLEAARFEISL--EHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEE 306
            +I  LE+ N LL     E+    E   L +E  +               A +  E  C+E
Sbjct: 352  QIGKLEKENALLSKELQEMKEVEEFESLEEEFRKEHEDVLQNEICDLRRAVEGSELQCQE 411

Query: 307  KTEIEEKGSLEIANMTELTKKIELL--EHLNCQIRQTNKELENKLATMGTESKAVSSPSK 364
                 E  ++E+   ++  ++++ +  + L  ++ +  + L +    +G ++K   +  +
Sbjct: 412  LQNKLESVTVELKKKSDFAEELQTMNGKDLVQEVAELRRSLHDAEG-LGRDAKKEWAILR 470

Query: 365  KGSPLISRKSGRNTAS--KMKSPWSQLSSETLNQDTDKKINKNEIAK-LEMVIQSLNK-- 419
              +  +       TAS  KM++    L  +   + +  K  + ++ K L +      K  
Sbjct: 471  SQNLSLEESVVTLTASHNKMEAEVGSLRHQLSVEKSHNKQMQTDLQKELNVAFDENTKLT 530

Query: 420  DLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIA 479
             L+D +   +  D            K+ L A  + E     +  SL  +    + + +  
Sbjct: 531  ALLDGKVPKNLIDAVELERSAANLTKE-LTASREAEEALRGQLASLQVLPDQVQHLGKQL 589

Query: 480  KVQEQLKQELNDEIKDVN--VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKL 537
            +  EQ K  L ++I ++   +KDL EKL  +E    +  +EI    +  +  + N +L+ 
Sbjct: 590  EQSEQQKLSLEEKINEMQQLLKDLEEKLVDSENS-RETEEEISKELQEQLN-ELNRELQC 647

Query: 538  KQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESD 597
            ++ +K   N    +++ + I  LT E      ++ +  E+    Q  L  +         
Sbjct: 648  ERAEKE-QNVHSSTETERLISSLTAERDQFRAELQDNVEKAAEAQAVLHSFQDDIQHHR- 705

Query: 598  VYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCS 657
              +K  ++  L+E +   I  L  +   +  EL   ++  +E       I  L ++Q   
Sbjct: 706  --QKNADLMKLSEQKDSDIENLSRELQRVCDELAEARRSGEEERQLQPVIDSLTAEQ--- 760

Query: 658  EIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQEN 717
                   + +   L+  K+EL  +I+ L+ +K+QL   ++D     E +   LQ    + 
Sbjct: 761  -----DQQGRFAILNREKEELQEIIDVLRQEKQQLKAELEDRMELIEQLQTSLQAANDQR 815

Query: 718  MDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFG-IDAKIQERDLYIENIESELSKYKS 776
            + L D+L++      SEL+         +IQ  FG ++ ++ E+    + +   +  ++ 
Sbjct: 816  IQLEDELQRN-----SELII--------EIQCHFGRLEEELLEQK---QKMADNMKLWEQ 859

Query: 777  RICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRV 836
            +   LE+    + ++  S + + D L   + EK      YT +++EL +R  V +  DR 
Sbjct: 860  KESDLEQQRTSLTEQLESAQSERDAL---MLEKDSRTHTYTEEKEEL-HRNLVTLSKDRE 915

Query: 837  VEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKAN--RTDLAESES- 893
              ++++E+       Q+K Q+  E    +++ L  +QQH  +  E+ N  ++DL E+   
Sbjct: 916  ELQEMVEMLR-----QEKQQLRTELEDRMEM-LQQLQQHLESSKEEVNQLKSDLEENVEL 969

Query: 894  -TKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFN--TQIESAIRDKKV-LNEK 949
                + +L ++++    +  E         +E  DL+      T+ +  ++ + V L E 
Sbjct: 970  IQCLKEELLNIKAERDALWSEKDASCSNSLQEKSDLQSRLTSLTEEKEELQSRLVALGED 1029

Query: 950  YEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYIN 1009
             E     +  L  + +E ++++ +L+   EEL +  L  + ++ +  ++     TE+   
Sbjct: 1030 KEALQNSLISLTEEKEELQSHLTSLSKEKEEL-QSRLMALGEYKEDVKSSLMSLTEEKEA 1088

Query: 1010 EINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSK 1069
              ++L AL + K E + +  Q ++  +    S +       A   + L ++ EE + +  
Sbjct: 1089 LQSRLMALGEDK-EALQSSVQSLSKEKEELQSRLMALGEDKADVKSSLMSLTEEKEALQS 1147

Query: 1070 QLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVD 1129
            +L+   +  E LQ  V+    + +EL+   +    +    +   +S T E   ++  +  
Sbjct: 1148 RLMALGEDKEALQSSVQSLSKEKEELQSRLMALGEDKEDVKSSFMSLTEE--KEELQSHL 1205

Query: 1130 XXXXXXXXXXXXLKVQEEEEFIQ--------ERSVLQEQSAKLNTELQECYTKIIQLETL 1181
                        + + EE+E +Q        E+  LQ     L+ E +E  ++++ L   
Sbjct: 1206 TALKKEDLQSSLMSLTEEKEALQSHLMALGEEKEALQSSVQSLSKEKEELQSRLMALGED 1265

Query: 1182 NTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQ 1241
              ++    +   E+  +L+S L  L+ E ++L S +A L       +  R   + E  K+
Sbjct: 1266 KADVKSSFMSLTEEKEELQSHLTSLSKEKEDLHSHLASLVEE-KEELQSRLVSLGE-EKE 1323

Query: 1242 HLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQD 1301
             L +      + + EL+  L++   + E+L   ++S  +E   K      + SL  + ++
Sbjct: 1324 DLQRSLLSLTEEKEELQSHLTSLSKEKEELKSRLESLCEE---KEALQNSLMSLSGEKEE 1380

Query: 1302 KEEHLRNLQEKYADVINQIEILRSE---IEDEKVAFXXXXXXXXXXXXXXXXDLRTENQS 1358
             + +L +L E+  +    +E+LR E   ++ E                    D++TE   
Sbjct: 1381 LQSNLTSLSEEREEFQKILEMLRQEKQHLQAEMQERVDSLQTEISTVNKKMDDIKTERDG 1440

Query: 1359 YKQMQEQSI-LNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIY 1417
                +E S   +  E+  Q + +S             +   E + L    + E+K   + 
Sbjct: 1441 LMSEKEASCWASSQEQELQSRLTSLREEKEEMSELLEMVKREEQQL----RTEMKCKLVA 1496

Query: 1418 QKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQ 1477
             +T     TLT++        Q+  E + R+  L  EKE EL I  L+   +    E   
Sbjct: 1497 LQTE--VRTLTEKLQGISETSQENEEMQNRLASLGIEKE-ELQISALQQETDGGEREAEL 1553

Query: 1478 KESEIERVKLIEELNVKITESVS--LNKQVAELNKALEEEVAKTNEMQTALENQEIEIVT 1535
            ++  +E    I  L  ++   +   +  Q+ + NK ++E +    +   A    ++ +  
Sbjct: 1554 QQLLVEANSSIAALQDQLDRLIKNPIMSQLQDSNKQIQEFLGTFQQFIEACSRMKVTVQN 1613

Query: 1536 LNDEITN 1542
                + N
Sbjct: 1614 EAQRVNN 1620



 Score =  111 bits (266), Expect = 2e-22
 Identities = 212/1140 (18%), Positives = 477/1140 (41%), Gaps = 87/1140 (7%)

Query: 451  QLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEE 510
            QLQ E +  ++  + + V T++  V       E LK   ND +      +L EKL+S  +
Sbjct: 24   QLQREQEDRIKNLTKLLV-TSSNLVPFKKSPAETLKLNRNDPLWRKRAAELEEKLQSEAQ 82

Query: 511  QITQLNDEIDAANKNM----IKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHH 566
            Q  +  ++I ++ +      ++++S  + K + ++K+  +  + ++   ++    ++ H 
Sbjct: 83   QKHEALEKIHSSEQRAAELELQLQSEAQQKHEALEKSHSSEQRAAELELQLQSEAQQKHE 142

Query: 567  LSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDL 626
              +K    E+    L+L L      +     + K     +  AE  L+  S  + Q  + 
Sbjct: 143  ALEKSHSSEQRAAELELQL--QSEAQQKHEALEKSHSSEQRAAELELQLQSEAQ-QNHEA 199

Query: 627  VQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLK 686
            +++ H  +Q+  E+E +L    Q ++ Q    ++  H  EQ  A      EL L +++  
Sbjct: 200  LEKSHSSEQRAAELELQL----QSEAQQKHEALEKSHSSEQRAA------ELELQLQSEA 249

Query: 687  LDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLE-KMSAEKISELLAKINHEE-- 743
              K +    I   E    ++  +LQ+  Q+  + TDK E  +   ++   L++ +H +  
Sbjct: 250  QQKHEALEKIHSSEQRAAELELQLQSEAQQKHEATDKAELLLRVAELERQLSERSHVQGG 309

Query: 744  -QSKIQTQFG-----IDAKIQERDLYI---ENIESELSKYKSRICRLEESIAVMEDRRYS 794
               +++  F       +A   E+DL +   + ++ EL  +  +I +LE+  A++      
Sbjct: 310  ADEQVRRDFAETIQLCEALASEKDLMVTERDYLKQELGMFLEQIGKLEKENALLSKELQE 369

Query: 795  LERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKK 854
            + ++ ++  S  +E +K + +  + ++E+ +    +   +   ++   ++E    EL+KK
Sbjct: 370  M-KEVEEFESLEEEFRKEHED--VLQNEICDLRRAVEGSELQCQELQNKLESVTVELKKK 426

Query: 855  NQILLE-ENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHE 913
            +    E +  N +  + ++ +   +L +       A+ E    ++Q   LE ++  +T  
Sbjct: 427  SDFAEELQTMNGKDLVQEVAELRRSLHDAEGLGRDAKKEWAILRSQNLSLEESVVTLTAS 486

Query: 914  HQTLIVQKKKEIEDLEIE--FNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNI 971
            H  +  +       L +E   N Q+++ +  +K LN  +++N +    L+ ++   KN I
Sbjct: 487  HNKMEAEVGSLRHQLSVEKSHNKQMQTDL--QKELNVAFDENTKLTALLDGKVP--KNLI 542

Query: 972  ENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYI-NEINKLNALLKQKDEEIIALNQ 1030
            + + +     N +  EL      ++  +    + Q + +++  L   L+Q +++ ++L +
Sbjct: 543  DAVELERSAAN-LTKELTASREAEEALRGQLASLQVLPDQVQHLGKQLEQSEQQKLSLEE 601

Query: 1031 KINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDS-KQHNEELQILVREQD 1089
            KIN  Q     ++ D E KL       EN  E  + +SK+L +   + N ELQ    E++
Sbjct: 602  KINEMQ----QLLKDLEEKLVD----SENSRETEEEISKELQEQLNELNRELQCERAEKE 653

Query: 1090 DQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEE-E 1148
              +    E           TE +I S T E     A   D               Q++ +
Sbjct: 654  QNVHSSTE-----------TERLISSLTAERDQFRAELQDNVEKAAEAQAVLHSFQDDIQ 702

Query: 1149 EFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNT 1208
               Q+ + L + S + +++++       +L+ +  EL       +E+  QL+  ++ L  
Sbjct: 703  HHRQKNADLMKLSEQKDSDIENLSR---ELQRVCDELAEARRSGEEE-RQLQPVIDSLTA 758

Query: 1209 ENDN-----LLSTVAELRSSISSAVDQRGFEI-AELW-KQHLAQREADFQKTEHELRVQL 1261
            E D      +L+   E    I   + Q   ++ AEL  +  L ++     +  ++ R+QL
Sbjct: 759  EQDQQGRFAILNREKEELQEIIDVLRQEKQQLKAELEDRMELIEQLQTSLQAANDQRIQL 818

Query: 1262 SAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIE 1321
                 +  +L+  +Q        +++  +Q  +   KL +++E   +L+++   +  Q+E
Sbjct: 819  EDELQRNSELIIEIQCHFGRLEEELLEQKQKMADNMKLWEQKE--SDLEQQRTSLTEQLE 876

Query: 1322 ILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSS 1381
              +SE +   +                  +L T ++  +++QE  +  + +E  QL+   
Sbjct: 877  SAQSERDALMLEKDSRTHTYTEEKEELHRNLVTLSKDREELQEM-VEMLRQEKQQLRTEL 935

Query: 1382 XXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEF------- 1434
                         +  ++ +V +L   LE ++ E+ Q   E  + +    D         
Sbjct: 936  EDRMEMLQQLQQHLESSKEEVNQLKSDLE-ENVELIQCLKEELLNIKAERDALWSEKDAS 994

Query: 1435 -ENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNV 1493
              N  Q+  + + R+  LT EKE EL    + + E+    +        E+ +L   L  
Sbjct: 995  CSNSLQEKSDLQSRLTSLTEEKE-ELQSRLVALGEDKEALQNSLISLTEEKEELQSHLTS 1053

Query: 1494 KITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSK 1553
               E   L  ++  L +  E+  +    +    E  +  ++ L ++   LQ+ V++ S +
Sbjct: 1054 LSKEKEELQSRLMALGEYKEDVKSSLMSLTEEKEALQSRLMALGEDKEALQSSVQSLSKE 1113



 Score = 77.4 bits (182), Expect = 3e-12
 Identities = 170/888 (19%), Positives = 364/888 (40%), Gaps = 71/888 (7%)

Query: 237  QRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLA 296
            Q L K+ E    R+ +L E    ++++   ++ E   L   L                L+
Sbjct: 1108 QSLSKEKEELQSRLMALGEDKADVKSSLMSLTEEKEALQSRLMALGEDKEALQSSVQSLS 1167

Query: 297  KQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTES 356
            K+  E         E+K  ++ + M+   +K EL  HL    ++   +L++ L ++  E 
Sbjct: 1168 KEKEELQSRLMALGEDKEDVKSSFMSLTEEKEELQSHLTALKKE---DLQSSLMSLTEEK 1224

Query: 357  KAVSSP-SKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQ 415
            +A+ S     G    + +S   + SK K    +L S  +    DK   K+    L    +
Sbjct: 1225 EALQSHLMALGEEKEALQSSVQSLSKEK---EELQSRLMALGEDKADVKSSFMSLTEEKE 1281

Query: 416  SLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQL-QLEHQQHMEGPSLIHVGTNTED 474
             L   L     +  EK+            K+ L ++L  L  ++     SL+ +    E+
Sbjct: 1282 ELQSHLTS---LSKEKEDLHSHLASLVEEKEELQSRLVSLGEEKEDLQRSLLSLTEEKEE 1338

Query: 475  ----VNEIAKVQEQLKQELND--EIKDVNVKDLIEKLKSAEE---QITQLNDEIDAANKN 525
                +  ++K +E+LK  L    E K+     L+      EE    +T L++E +   K 
Sbjct: 1339 LQSHLTSLSKEKEELKSRLESLCEEKEALQNSLMSLSGEKEELQSNLTSLSEEREEFQKI 1398

Query: 526  MIKVKSNHKLKLKQMQKTIDNF-SKVSDSNKEIVRL-TEELHHLSQKVAE--LEEEKGNL 581
            +  ++   +    +MQ+ +D+  +++S  NK++  + TE    +S+K A      ++  L
Sbjct: 1399 LEMLRQEKQHLQAEMQERVDSLQTEISTVNKKMDDIKTERDGLMSEKEASCWASSQEQEL 1458

Query: 582  QLHLVDYDSGRMIESDVYKKMIEMENLAETRLKA-ISLLESQKFDLVQELHIL---QQKY 637
            Q  L      +   S++ + +   E    T +K  +  L+++   L ++L  +    Q+ 
Sbjct: 1459 QSRLTSLREEKEEMSELLEMVKREEQQLRTEMKCKLVALQTEVRTLTEKLQGISETSQEN 1518

Query: 638  DEVEDKLADI----SQLQSDQVCSEIKSVHLEEQIDAL--SASKKELALVIENLKLDKEQ 691
            +E++++LA +     +LQ   +  E      E ++  L   A+    AL  +  +L K  
Sbjct: 1519 EEMQNRLASLGIEKEELQISALQQETDGGEREAELQQLLVEANSSIAALQDQLDRLIKNP 1578

Query: 692  LYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQF 751
            +   ++D     ++ +   Q +I+    +   ++   A++++    K   +   K  +  
Sbjct: 1579 IMSQLQDSNKQIQEFLGTFQQFIEACSRMKVTVQN-EAQRVNNPCPKFVPKSSRKSYSTV 1637

Query: 752  GIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQK 811
                +IQ     +  +E  L +       L E +  ++  R + E K   L   L  + +
Sbjct: 1638 -CQLRIQTLQCLLNTME-YLQEQAQVYRNLFEDL--LKKDRLTFEEKC--LQDVLLCRDQ 1691

Query: 812  AYSEYTIQEDELVN----RLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQI 867
             YS +++++++       RL  L+D   V  K++  I    ++L         E   L  
Sbjct: 1692 TYS-FSVRDEDFNKLWRYRLTELLDKRNVYMKKMQTIW---EKLWANMSYFTNE---LSA 1744

Query: 868  SLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIED 927
             + + +     L  K     +   E  +  T +     +L+++  E+  +     +E++ 
Sbjct: 1745 EVREHESFKEQLQAKVGLDQILGGELQRRSTMVETRNIHLQQLREENSNMC----EELKC 1800

Query: 928  LEIEFNTQI-ESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNL 986
            L+++ ++++ E   R   +L E+ +       QL  +LQ+ ++ +  +N   ++L K  L
Sbjct: 1801 LQVQNDSELREERSRRCSMLQEEVQGAAFDTQQLLLKLQQAEDKVRLMNAEKQQLEKDQL 1860

Query: 987  EL---IDKH---VQKQQTQSPDYTEQYINEINKLNALLKQKDE-----EIIALNQKINNA 1035
            ++   +  H    Q  QT+  D   Q  ++ N +  L  Q  E      ++ +   +   
Sbjct: 1861 QVHGRLSSHKEATQLLQTELQDSRAQVQDQDNTIQTLRNQLKEAQVYRSVLIITAAVGTF 1920

Query: 1036 QVSYMSMVSDYE---SKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEE 1080
            +   ++ VS  E   +K+ +F   L   EE ++++ + L  S+QH EE
Sbjct: 1921 EGFCLTDVSSAEKCFAKIQKFKVLLNTKEESVRKLKELLRKSQQHGEE 1968



 Score = 67.3 bits (157), Expect = 3e-09
 Identities = 169/878 (19%), Positives = 349/878 (39%), Gaps = 86/878 (9%)

Query: 691  QLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQ 750
            QL      L+ ++ED +  L   +  + +L    +K  AE +     K+N  +    +  
Sbjct: 17   QLLQEKDQLQREQEDRIKNLTKLLVTSSNLVP-FKKSPAETL-----KLNRNDPLWRKRA 70

Query: 751  FGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQ 810
              ++ K+Q           ++   + R   LE  +     +++    K     S+  E++
Sbjct: 71   AELEEKLQSEAQQKHEALEKIHSSEQRAAELELQLQSEAQQKHEALEK-----SHSSEQR 125

Query: 811  KAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQN------ 864
             A  E  +Q +      A+   H        LE++ ++ E Q+K++ L + + +      
Sbjct: 126  AAELELQLQSEAQQKHEALEKSHSSEQRAAELELQLQS-EAQQKHEALEKSHSSEQRAAE 184

Query: 865  LQISL-SDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKK 923
            L++ L S+ QQ++ AL EK++ +   E  + + + QL+  E+  K    E      Q+  
Sbjct: 185  LELQLQSEAQQNHEAL-EKSHSS---EQRAAELELQLQS-EAQQKHEALEKSHSSEQRAA 239

Query: 924  EIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNK 983
            E+E L+++   Q +    +K   +E+    +E   Q EAQ +    +   L + V EL +
Sbjct: 240  ELE-LQLQSEAQQKHEALEKIHSSEQRAAELELQLQSEAQQKHEATDKAELLLRVAELER 298

Query: 984  MNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMV 1043
               E    HVQ    +       +   I    AL  +KD  ++     +      ++  +
Sbjct: 299  QLSER--SHVQGGADEQ--VRRDFAETIQLCEALASEKDL-MVTERDYLKQELGMFLEQI 353

Query: 1044 SDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFE 1103
               E + A  + +L+ M+E  +  S +    K+H + LQ       ++I +L+      E
Sbjct: 354  GKLEKENALLSKELQEMKEVEEFESLEEEFRKEHEDVLQ-------NEICDLRRAVEGSE 406

Query: 1104 MNIPKTEGMIISSTIE-----PMSDDANNVDXXXXXXXXXXXXLKVQEEE----EFIQER 1154
            +   + +  + S T+E       +++   ++              + + E    +  +E 
Sbjct: 407  LQCQELQNKLESVTVELKKKSDFAEELQTMNGKDLVQEVAELRRSLHDAEGLGRDAKKEW 466

Query: 1155 SVLQEQSAKLNTE---LQECYTKI-IQLETLNTELTGHDVVNQEQINQLKSKLEQLNTEN 1210
            ++L+ Q+  L      L   + K+  ++ +L  +L+     N++    L+ +L     EN
Sbjct: 467  AILRSQNLSLEESVVTLTASHNKMEAEVGSLRHQLSVEKSHNKQMQTDLQKELNVAFDEN 526

Query: 1211 DNLLSTV-AELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYE 1269
              L + +  ++  ++  AV+      A L K+  A REA     E  LR QL++ +   +
Sbjct: 527  TKLTALLDGKVPKNLIDAVELER-SAANLTKELTASREA-----EEALRGQLASLQVLPD 580

Query: 1270 QLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIED 1329
            Q+    +   Q E  K+       SL+ K+ + ++ L++L+EK  D  N  E    EI  
Sbjct: 581  QVQHLGKQLEQSEQQKL-------SLEEKINEMQQLLKDLEEKLVDSENSRET-EEEISK 632

Query: 1330 EKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXX 1389
            E                    +L  E Q  +  +EQ++ +  E    +   +        
Sbjct: 633  E--------------LQEQLNELNRELQCERAEKEQNVHSSTETERLISSLTAERDQFRA 678

Query: 1390 XXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIE 1449
                 V  A A+   + H  +       QK  +      Q++ + EN+ ++L      + 
Sbjct: 679  ELQDNVEKA-AEAQAVLHSFQDDIQHHRQKNADLMKLSEQKDSDIENLSRELQRVCDELA 737

Query: 1450 DLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELN 1509
            +     E E   L+  +       +   + + + R K  EEL  +I + +   KQ  +L 
Sbjct: 738  EARRSGEEERQ-LQPVIDSLTAEQDQQGRFAILNREK--EELQ-EIIDVLRQEKQ--QLK 791

Query: 1510 KALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMV 1547
              LE+ +    ++QT+L+    + + L DE+     ++
Sbjct: 792  AELEDRMELIEQLQTSLQAANDQRIQLEDELQRNSELI 829



 Score = 62.9 bits (146), Expect = 7e-08
 Identities = 149/757 (19%), Positives = 311/757 (41%), Gaps = 79/757 (10%)

Query: 838  EKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVE--KANRTD-LAESEST 894
            +K L ++  E  +LQ++ +  ++    L ++ S++     +  E  K NR D L    + 
Sbjct: 12   KKVLSQLLQEKDQLQREQEDRIKNLTKLLVTSSNLVPFKKSPAETLKLNRNDPLWRKRAA 71

Query: 895  KYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNI 954
            + + +L+  E+  K   HE    I   ++   +LE++  ++ +      +  +   ++  
Sbjct: 72   ELEEKLQS-EAQQK---HEALEKIHSSEQRAAELELQLQSEAQQKHEALEKSHSSEQRAA 127

Query: 955  EYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDY-TEQYINEIN- 1012
            E   QL+++ Q+    +E  + + +   ++ L+L  +  QK +     + +EQ   E+  
Sbjct: 128  ELELQLQSEAQQKHEALEKSHSSEQRAAELELQLQSEAQQKHEALEKSHSSEQRAAELEL 187

Query: 1013 KLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLL 1072
            +L +  +Q  E +          + S+ S     E + A+   +L++  ++     ++  
Sbjct: 188  QLQSEAQQNHEAL----------EKSHSS-----EQRAAELELQLQSEAQQKHEALEKSH 232

Query: 1073 DSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXX 1132
             S+Q   EL++ ++ +  Q  E  E   + E    + E + + S  +   +  +  +   
Sbjct: 233  SSEQRAAELELQLQSEAQQKHEALEKIHSSEQRAAELE-LQLQSEAQQKHEATDKAE--- 288

Query: 1133 XXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQL-ETLNTE----LTG 1187
                     L+V E E  + ERS +Q      + +++  + + IQL E L +E    +T 
Sbjct: 289  -------LLLRVAELERQLSERSHVQ---GGADEQVRRDFAETIQLCEALASEKDLMVTE 338

Query: 1188 HDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQRE 1247
             D + QE +     ++ +L  EN  L   + E++      V++  FE  E  ++   + E
Sbjct: 339  RDYLKQE-LGMFLEQIGKLEKENALLSKELQEMKE-----VEE--FESLE--EEFRKEHE 388

Query: 1248 ADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNK--LQDKEEH 1305
               Q    +LR  +   E + ++L + ++S T E   K    E++ ++  K  +Q+  E 
Sbjct: 389  DVLQNEICDLRRAVEGSELQCQELQNKLESVTVELKKKSDFAEELQTMNGKDLVQEVAEL 448

Query: 1306 LRNLQEKYA---DVINQIEILRSE---IEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSY 1359
             R+L +      D   +  ILRS+   +E+  V                   L  E    
Sbjct: 449  RRSLHDAEGLGRDAKKEWAILRSQNLSLEESVVTLTASHNKMEAEVGSLRHQLSVEKSHN 508

Query: 1360 KQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQK 1419
            KQMQ      +N    +  K +               + E     LT +L     E  + 
Sbjct: 509  KQMQTDLQKELNVAFDENTKLTALLDGKVPKNLIDAVELERSAANLTKEL-TASREAEEA 567

Query: 1420 THEYTITLTQRNDEFENVRQQLVEYEKR---IEDLTYEKESELAILRLKMHENANHYETM 1476
                  +L    D+ +++ +QL + E++   +E+   E +  L  L  K+ ++ N  ET 
Sbjct: 568  LRGQLASLQVLPDQVQHLGKQLEQSEQQKLSLEEKINEMQQLLKDLEEKLVDSENSRET- 626

Query: 1477 QKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTL 1536
              E EI + +L E+LN        LN+++       E+ V  + E +  + +   E    
Sbjct: 627  --EEEISK-ELQEQLN-------ELNRELQCERAEKEQNVHSSTETERLISSLTAERDQF 676

Query: 1537 NDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLD 1573
              E+ +  N+ +A+ ++   H SF  D +  R +  D
Sbjct: 677  RAELQD--NVEKAAEAQAVLH-SFQDDIQHHRQKNAD 710


>UniRef50_Q22SA1 Cluster: Putative uncharacterized protein; n=1;
            Tetrahymena thermophila SB210|Rep: Putative
            uncharacterized protein - Tetrahymena thermophila SB210
          Length = 1893

 Score =  153 bits (372), Expect = 3e-35
 Identities = 252/1390 (18%), Positives = 577/1390 (41%), Gaps = 90/1390 (6%)

Query: 254  EEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEK 313
            +E  + L+    ++ L+ S L +   Q                  SI+   +  T  E+K
Sbjct: 342  KEIEESLKHENDDLKLKISMLHESYSQINKSMIGGAAGTKPDISFSIQKDLDIATTYEQK 401

Query: 314  GSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRK 373
              L    +    K++E     N + ++ N EL +    +  +   V   + +G  +   +
Sbjct: 402  VLLIQKELERSHKELEDYRKKNQEAQKKNDELNHTCTQLNEQLNTVIQKTIEGKTV---Q 458

Query: 374  SGRNTASKMKSPWSQLSSETLNQDTDKKIN-KNEIAKLE--MVIQSLNKDLVDKEYVISE 430
                   ++K  + +   E   Q +    N KN+I++LE  ++ +      +  + +   
Sbjct: 459  IDEYKLDQVKQQYERKLYEEQQQYSQNLQNMKNQISELETSLIQEKATTQKLQTDILNLT 518

Query: 431  KDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELN 490
             D                  Q++    ++    S+     N E +N   K+ E       
Sbjct: 519  NDQIIVGSNNTKSSPSYNNQQIENIKSEYENIISVQRQQFNQELLNVNQKIYELESSLTT 578

Query: 491  DEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKV 550
            ++  +  ++  I+ L +   + +++ D + +++ N  + K  H+  L  ++K   +  ++
Sbjct: 579  EKFNNKKLQGEIQNLSTLVAEQSRIYDPVASSSANSEETKRKHEEMLSNLRK--QHQEEI 636

Query: 551  SDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLA- 609
            +  + +I  L  +L +      +L+ E  N+ +  ++ +S ++ E+ +  K ++++ L  
Sbjct: 637  NRISSQIALLEYQLANEKTTNQKLQNEIQNISISQININSTKIPETQIQDKELQIQQLKK 696

Query: 610  ---ETRLKAISLLESQKFDLVQELHILQQKYDE-------VEDKLADISQLQSDQVCSEI 659
               ET L      E +   + +++ IL+Q   E       +E ++ +IS    +    EI
Sbjct: 697  QFEETVLNQKIAYEQEVQKMNKQVEILEQSLIEEKTNSKKLEYEIQNISCQYGNNNDEEI 756

Query: 660  KSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDK--EDIMNKLQNYIQEN 717
            ++  L++Q++ L    + L +  +N++L + QL       EN+   +++++++QN    N
Sbjct: 757  QN--LKKQVEELH--NQNLKINQQNMELTQTQLAMAQLANENNPNTDNLLSEIQNLKNLN 812

Query: 718  MDLTDKLEKMSAEKISELLAKINHEE---QSKIQTQFGIDAKIQER-DLYIENIESELSK 773
              L  K E++   K  E+  +        Q   Q  F +   ++ER +  + N  + +  
Sbjct: 813  ETLNLKNEELVQAKEKEIQERTEEYRMIIQKMEQESFSVIQHVEERGEKEVRNQANNMDS 872

Query: 774  --YKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLM 831
              Y+++I  L E+I  ++ +         Q    L E  +    Y  +ED L+N     +
Sbjct: 873  ILYENQIEELNETIRQLQQQLEVQHVPNSQ--KQLTESPEVVRIYK-KEDNLINIQENFV 929

Query: 832  DHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVE-KANRTDL-- 888
            + D     QL + + + + +  K +++ +  +  ++    ++Q YN   + + N + +  
Sbjct: 930  NQDEEDSSQLQQKDEQQEIISLKEEVVKQREECDKLK-EKIEQEYNTNEDLRQNLSKIVT 988

Query: 889  -AESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLN 947
             +E + TKY+ Q+ D+ES L      H   I +KK+ IEDLE       E     ++  +
Sbjct: 989  ESEEQDTKYKKQISDIESKL----FLHIKEIAEKKQLIEDLEKSKKALAEQVFSYEEKEH 1044

Query: 948  EKYEKNIEYVTQL-------EAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQ- 999
              +++ +E   QL       + Q+QE +      +  +   N+M +  +   +Q+ Q++ 
Sbjct: 1045 NLHQQVVEAKEQLAKIQAETKFQIQEAEKRHSTSSSQILNENEMKISKLKSEIQQVQSEY 1104

Query: 1000 ---SPDYTEQYINEINKLNA---LLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQF 1053
                    +QY  +IN+LN+    L  + +E  AL ++        + +   +E ++A+ 
Sbjct: 1105 QLKIQQSEQQYTTQINQLNSQIQTLTNQTQEKNALIEEKERKIEEQIQVAKKFEERIAEM 1164

Query: 1054 TTKLENM---EEEMQRVSKQLLD--SKQHNEELQILVREQDDQIKELKETKLTFEMNIPK 1108
              + E++   +++++  SKQL +   K++  +L + +        EL+ +K  ++  +  
Sbjct: 1165 VKEREDLLKHDKDIELQSKQLKEIMEKEYKHQLDVQISLAKKLETELEASKQKYQSQVDL 1224

Query: 1109 TEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQ----------ERSVLQ 1158
                +    +  +  + N                +++E+   +Q          E+++  
Sbjct: 1225 FNEQVKKCQVLEVQLNENKEKQQQLELQWNNQKKEIEEQNNQVQFELKNKLSELEKTIAS 1284

Query: 1159 E--QSAKLNTELQECYTKIIQLE-TLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLS 1215
            +  +  +L  +L++   ++ Q+   LN + T  ++  +E  + L SK++Q++ EN+   +
Sbjct: 1285 QTHEEHQLKNDLEKYQNQLAQIAGQLNQKETQLNLFKKEN-SALSSKIQQIDEENN---T 1340

Query: 1216 TVAELRSSISSAVDQRGFEIAELWKQHLAQRE-ADFQKTEHELRV--QLSAFESKYEQLL 1272
               EL   I     Q+  E+ + + + + Q E    +K E++L    ++   +  YE LL
Sbjct: 1341 EKQELTQKIEKLEAQQA-ELQQKYDKQVKQYERVKKEKEENDLLADEEIHKLKQNYEALL 1399

Query: 1273 DSVQSSTQEETNKIVTMEQVTSLQNKLQD-KEEHLRNLQEKYADVI-NQIEILRSEIEDE 1330
            +S +++ ++   + +T      +Q    D K     +  +K    +  ++E L+ ++ ++
Sbjct: 1400 ESEKAAKEDVKKEFITKVDELKIQVARHDTKTRQTEDKHQKQVKTLEKEVESLK-QLNNK 1458

Query: 1331 KVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXX 1390
            K+                   L ++ +  +Q     +   NEE   L +           
Sbjct: 1459 KIETMKTIQETCKKLEEEKGQLESQYKKKEQKFIDELKEKNEEIEVLTQQKKKINEIQNE 1518

Query: 1391 XXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIED 1450
               ++   + KV EL+   E    E+ Q++ E  I++    +  +  +Q + EYE +I +
Sbjct: 1519 LQEKLIAEQKKVSELSENQEKLAKEL-QQSEEKKISI--EKEWIQKNQQTIAEYESKISE 1575

Query: 1451 LTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNK 1510
               E E  L+  +    +      +   + E E  +    LN KI    S  K   E  K
Sbjct: 1576 KDAEFEKILSSKQGDSSQQIQELSSKNMKQEKEFREKENNLNNKINTLQSSVKNHEEKLK 1635

Query: 1511 ALEEEVAK-TNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRD 1569
            +LEEE +K + ++   +     EI T    I   QN + A   +I++      + +  + 
Sbjct: 1636 SLEEENSKLSTQLSEKIAVLNKEIDTHKASIKENQNQIEAFEKEIKEKNQIIKNLESDKS 1695

Query: 1570 EQLDNTMNKE 1579
            +  + T+ +E
Sbjct: 1696 DLEEKTLKQE 1705



 Score =  145 bits (352), Expect = 8e-33
 Identities = 275/1419 (19%), Positives = 619/1419 (43%), Gaps = 177/1419 (12%)

Query: 320  NMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTA 379
            N+  +  +I  LE    Q + T ++L+  +  +  +   V S + K SP  + +   N  
Sbjct: 485  NLQNMKNQISELETSLIQEKATTQKLQTDILNLTNDQIIVGSNNTKSSPSYNNQQIENIK 544

Query: 380  SKMKSPWS----QLSSETLNQ-------DTDKKINKNEIAKLEMVIQSLNKDLVDKEYVI 428
            S+ ++  S    Q + E LN        ++     K    KL+  IQ+L+  + ++  + 
Sbjct: 545  SEYENIISVQRQQFNQELLNVNQKIYELESSLTTEKFNNKKLQGEIQNLSTLVAEQSRIY 604

Query: 429  SEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQE 488
                +            + +++ L+ +HQ+ +   S        +  NE    Q+   + 
Sbjct: 605  DPVASSSANSEETKRKHEEMLSNLRKQHQEEINRISSQIALLEYQLANEKTTNQKLQNEI 664

Query: 489  LNDEIKDVNV------------KDL-IEKLKSA------------EEQITQLNDEIDAAN 523
             N  I  +N+            K+L I++LK              E+++ ++N +++   
Sbjct: 665  QNISISQININSTKIPETQIQDKELQIQQLKKQFEETVLNQKIAYEQEVQKMNKQVEILE 724

Query: 524  KNMIKVKSNHKLKLKQMQKTIDNFSKVSDSN-KEIVRLTEELHHLSQKVAELEEEKGNLQ 582
            +++I+ K+N K    ++Q     +   +D   + + +  EELH+ + K+ +   E    Q
Sbjct: 725  QSLIEEKTNSKKLEYEIQNISCQYGNNNDEEIQNLKKQVEELHNQNLKINQQNMELTQTQ 784

Query: 583  LHLVDYDSGRMIESD-VYKKMIEMENLAET-RLKAISLLESQKFDL---VQELHILQQKY 637
            L +    +     +D +  ++  ++NL ET  LK   L+++++ ++    +E  ++ QK 
Sbjct: 785  LAMAQLANENNPNTDNLLSEIQNLKNLNETLNLKNEELVQAKEKEIQERTEEYRMIIQKM 844

Query: 638  DE----VEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELA--LVIENLKLDKEQ 691
            ++    V   + +  + +     + + S+  E QI+ L+ + ++L   L ++++   ++Q
Sbjct: 845  EQESFSVIQHVEERGEKEVRNQANNMDSILYENQIEELNETIRQLQQQLEVQHVPNSQKQ 904

Query: 692  LYGT--IKDLENDKEDIMNKLQNYI-QENMDLTDKLEKMSAEKISELLAKI--NHEE--- 743
            L  +  +  +   +++++N  +N++ Q+  D +   +K   ++I  L  ++    EE   
Sbjct: 905  LTESPEVVRIYKKEDNLINIQENFVNQDEEDSSQLQQKDEQQEIISLKEEVVKQREECDK 964

Query: 744  -QSKIQTQFGIDAKIQER-DLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQ 801
             + KI+ ++  +  +++     +   E + +KYK +I  +E  + +    +   E+K  Q
Sbjct: 965  LKEKIEQEYNTNEDLRQNLSKIVTESEEQDTKYKKQISDIESKLFL--HIKEIAEKK--Q 1020

Query: 802  LGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVE--KQLLEIEHENK----ELQKKN 855
            L   L++ +KA +E     +E  + L     H +VVE  +QL +I+ E K    E +K++
Sbjct: 1021 LIEDLEKSKKALAEQVFSYEEKEHNL-----HQQVVEAKEQLAKIQAETKFQIQEAEKRH 1075

Query: 856  -----QILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRI 910
                 QIL E    +    S++QQ     V+   +  + +SE  +Y TQ+  L S ++ +
Sbjct: 1076 STSSSQILNENEMKISKLKSEIQQ-----VQSEYQLKIQQSEQ-QYTTQINQLNSQIQTL 1129

Query: 911  THEHQ---TLIVQKKKEIED-LEI--EFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQL 964
            T++ Q    LI +K+++IE+ +++  +F  +I   +++++ L  K++K+IE  ++   ++
Sbjct: 1130 TNQTQEKNALIEEKERKIEEQIQVAKKFEERIAEMVKEREDLL-KHDKDIELQSKQLKEI 1188

Query: 965  QEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQY----INEINKLNALLKQ 1020
             E K     L++ +    K+  EL +   QK Q+Q   + EQ     + E+       KQ
Sbjct: 1189 ME-KEYKHQLDVQISLAKKLETEL-EASKQKYQSQVDLFNEQVKKCQVLEVQLNENKEKQ 1246

Query: 1021 KDEEIIALNQKI------NNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQL--L 1072
            +  E+   NQK       N  Q    + +S+ E  +A  T +   ++ ++++   QL  +
Sbjct: 1247 QQLELQWNNQKKEIEEQNNQVQFELKNKLSELEKTIASQTHEEHQLKNDLEKYQNQLAQI 1306

Query: 1073 DSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXX 1132
              + + +E Q+ + ++++     K  ++  E N  K E   ++  IE +      +    
Sbjct: 1307 AGQLNQKETQLNLFKKENSALSSKIQQIDEENNTEKQE---LTQKIEKLEAQQAELQQKY 1363

Query: 1133 XXXXXXXXXLKVQEEE------EFIQE-----RSVLQEQSAKLNTELQECYTKI----IQ 1177
                     +K ++EE      E I +      ++L+ + A      +E  TK+    IQ
Sbjct: 1364 DKQVKQYERVKKEKEENDLLADEEIHKLKQNYEALLESEKAAKEDVKKEFITKVDELKIQ 1423

Query: 1178 LETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRG-FE-- 1234
            +   +T+    +  +Q+Q+  L+ ++E L   N+  + T+  ++ +     +++G  E  
Sbjct: 1424 VARHDTKTRQTEDKHQKQVKTLEKEVESLKQLNNKKIETMKTIQETCKKLEEEKGQLESQ 1483

Query: 1235 --------IAELWKQH-----LAQREADFQKTEHELRVQLSAFESKYEQLLDSVQS---S 1278
                    I EL +++     L Q++    + ++EL+ +L A + K  +L ++ +     
Sbjct: 1484 YKKKEQKFIDELKEKNEEIEVLTQQKKKINEIQNELQEKLIAEQKKVSELSENQEKLAKE 1543

Query: 1279 TQEETNKIVTMEQ---------VTSLQNKLQDKE-EHLRNLQEKYADVINQIEILRSEIE 1328
             Q+   K +++E+         +   ++K+ +K+ E  + L  K  D   QI+ L S+  
Sbjct: 1544 LQQSEEKKISIEKEWIQKNQQTIAEYESKISEKDAEFEKILSSKQGDSSQQIQELSSKNM 1603

Query: 1329 DEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSI---LNINEENAQLKKSSXXXX 1385
             ++  F                 ++   +  K ++E++      ++E+ A L K      
Sbjct: 1604 KQEKEFREKENNLNNKINTLQSSVKNHEEKLKSLEEENSKLSTQLSEKIAVLNKEIDTHK 1663

Query: 1386 XXXXXXXXRVNDAEAKVLE---LTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLV 1442
                    ++   E ++ E   +   LE   S++ +KT +    +   + + E  +    
Sbjct: 1664 ASIKENQNQIEAFEKEIKEKNQIIKNLESDKSDLEEKTLKQEEKIVLISTQLEQTKASKK 1723

Query: 1443 EYEKRIEDLTYEKESELAILRLKMHENANHY----ETMQKESEIERVKLIEELNV----K 1494
            E E ++     EKE+E  I+    ++    Y    E +Q  S    +   ++L      K
Sbjct: 1724 EIEDKLSRKIKEKETEQNIISQDYNQKIQVYKQTIEHLQNNSRQGDINFSQDLKFSQISK 1783

Query: 1495 ITESVSLNK---------QVAELNKALEEEVAKTNEMQTALEN--QEIEIVTLNDEITNL 1543
            IT+++S N             EL++ L   VA  ++ + ++ +   + E  ++  +++ +
Sbjct: 1784 ITDNLSDNNSHDEQADKLSGKELSQRLMSGVAALSQSRASVSSIRSKEETRSMYKKLSQM 1843

Query: 1544 QNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLD 1582
                 A  S  + +VS     K   D  ++NT N+E +D
Sbjct: 1844 SMATAAMMSVKRDYVSLKELAKSIDDHDVNNTSNQEDID 1882



 Score =  110 bits (265), Expect = 3e-22
 Identities = 219/1133 (19%), Positives = 476/1133 (42%), Gaps = 101/1133 (8%)

Query: 471  NTEDVNEIAKVQEQLKQELNDE---IKDVNVKDLI---EKLKSAEEQITQLNDEI----- 519
            NT   N I+ + +++  +L DE   + + N+K  +   +K K  EE +   ND++     
Sbjct: 301  NTSKFNSISMIPDKVSDKLIDEFQKLTESNLKFFMQNKQKWKEIEESLKHENDDLKLKIS 360

Query: 520  ------DAANKNMIKVKSNHKLKLK-QMQKTIDNFS----KVSDSNKEIVRLTEELHHLS 568
                     NK+MI   +  K  +   +QK +D  +    KV    KE+ R  +EL    
Sbjct: 361  MLHESYSQINKSMIGGAAGTKPDISFSIQKDLDIATTYEQKVLLIQKELERSHKELEDYR 420

Query: 569  QKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQ 628
            +K  E +++   L  H     + ++  + V +K IE + +     K    L+  K    +
Sbjct: 421  KKNQEAQKKNDELN-HTCTQLNEQL--NTVIQKTIEGKTVQIDEYK----LDQVKQQYER 473

Query: 629  ELHILQQKYDE-VEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKL 687
            +L+  QQ+Y + +++    IS+L++  +  + K+   + Q D L+ +  ++ +   N K 
Sbjct: 474  KLYEEQQQYSQNLQNMKNQISELETSLI--QEKATTQKLQTDILNLTNDQIIVGSNNTKS 531

Query: 688  DKEQLYGTIKDLENDKEDIMN-KLQNYIQENMDLTDKL----EKMSAEKIS--ELLAKIN 740
                    I++++++ E+I++ + Q + QE +++  K+      ++ EK +  +L  +I 
Sbjct: 532  SPSYNNQQIENIKSEYENIISVQRQQFNQELLNVNQKIYELESSLTTEKFNNKKLQGEIQ 591

Query: 741  H-----EEQSKI-----QTQFGIDAKIQERDLYIENI----ESELSKYKSRICRLEESIA 786
            +      EQS+I      +    +   ++ +  + N+    + E+++  S+I  LE  +A
Sbjct: 592  NLSTLVAEQSRIYDPVASSSANSEETKRKHEEMLSNLRKQHQEEINRISSQIALLEYQLA 651

Query: 787  VMEDRRYSLERKADQLG-SYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLL--- 842
              +     L+ +   +  S +        E  IQ+ EL  +       + V+ +++    
Sbjct: 652  NEKTTNQKLQNEIQNISISQININSTKIPETQIQDKELQIQQLKKQFEETVLNQKIAYEQ 711

Query: 843  EIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRD 902
            E++  NK+++   Q L+EE  N +    ++Q   N   +  N  D    E    + Q+ +
Sbjct: 712  EVQKMNKQVEILEQSLIEEKTNSKKLEYEIQ---NISCQYGNNND---EEIQNLKKQVEE 765

Query: 903  LESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIE---SAIRDKKVLNEKYE-KNIEYVT 958
            L +   +I  ++  L  Q +  +  L  E N   +   S I++ K LNE    KN E V 
Sbjct: 766  LHNQNLKINQQNMEL-TQTQLAMAQLANENNPNTDNLLSEIQNLKNLNETLNLKNEELVQ 824

Query: 959  QLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQ--YINEINKLNA 1016
              E ++QE       +   +E+ +   ++ +++  +K+     +  +   Y N+I +LN 
Sbjct: 825  AKEKEIQERTEEYRMIIQKMEQESFSVIQHVEERGEKEVRNQANNMDSILYENQIEELNE 884

Query: 1017 LLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQ 1076
             ++Q  +++   +   +  Q++    V     K        EN   + +  S Q L  K 
Sbjct: 885  TIRQLQQQLEVQHVPNSQKQLTESPEVVRIYKKEDNLINIQENFVNQDEEDSSQ-LQQKD 943

Query: 1077 HNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIIS-STIEPMSDDANNVDXXXXXX 1135
              +E+  L  E   Q +E  + K   E      E +  + S I   S++ +         
Sbjct: 944  EQQEIISLKEEVVKQREECDKLKEKIEQEYNTNEDLRQNLSKIVTESEEQDTKYKKQISD 1003

Query: 1136 XXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQ 1195
                  L ++E    I E+  L E   K    L E        +  + E   H++   +Q
Sbjct: 1004 IESKLFLHIKE----IAEKKQLIEDLEKSKKALAE--------QVFSYEEKEHNL--HQQ 1049

Query: 1196 INQLKSKLEQLNTENDNLLSTVAELRSSISSA--VDQRGFEIAELWKQHLAQREADFQKT 1253
            + + K +L ++  E    +   AE R S SS+  +++   +I++L K  + Q ++++Q  
Sbjct: 1050 VVEAKEQLAKIQAETKFQIQE-AEKRHSTSSSQILNENEMKISKL-KSEIQQVQSEYQLK 1107

Query: 1254 EHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDK-EEHLRNLQEK 1312
              +   Q +   ++    + ++ + TQE+   I   E+    Q ++  K EE +  + ++
Sbjct: 1108 IQQSEQQYTTQINQLNSQIQTLTNQTQEKNALIEEKERKIEEQIQVAKKFEERIAEMVKE 1167

Query: 1313 YADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINE 1372
              D++   + +  + +  K                    L TE ++ KQ  +  +   NE
Sbjct: 1168 REDLLKHDKDIELQSKQLKEIMEKEYKHQLDVQISLAKKLETELEASKQKYQSQVDLFNE 1227

Query: 1373 ENAQ---LKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQ 1429
            +  +   L+               + N+ + ++ E  +Q++    E+  K  E   T+  
Sbjct: 1228 QVKKCQVLEVQLNENKEKQQQLELQWNNQKKEIEEQNNQVQF---ELKNKLSELEKTIAS 1284

Query: 1430 RNDEFENVRQQLVEYEKRIEDLT---YEKESELAILRLKMHENANHYETMQKESEIERVK 1486
            +  E   ++  L +Y+ ++  +     +KE++L + + +    ++  + + +E+  E+ +
Sbjct: 1285 QTHEEHQLKNDLEKYQNQLAQIAGQLNQKETQLNLFKKENSALSSKIQQIDEENNTEKQE 1344

Query: 1487 LIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDE 1539
            L +++     +   L ++  +  K   E V K  E    L ++EI  +  N E
Sbjct: 1345 LTQKIEKLEAQQAELQQKYDKQVKQY-ERVKKEKEENDLLADEEIHKLKQNYE 1396



 Score = 72.9 bits (171), Expect = 7e-11
 Identities = 156/764 (20%), Positives = 330/764 (43%), Gaps = 88/764 (11%)

Query: 212  EDTKQQMTKMQENFIA----MEAEWKDEKQRLLKDIESK-DVRISSLEEANKLLEAARFE 266
            E+   +M K +E+ +     +E + K  K+ + K+ + + DV+IS  ++    LEA++ +
Sbjct: 1158 EERIAEMVKEREDLLKHDKDIELQSKQLKEIMEKEYKHQLDVQISLAKKLETELEASKQK 1217

Query: 267  ISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGS---LEIAN-MT 322
               +     +++++                +  ++ +  +K EIEE+ +    E+ N ++
Sbjct: 1218 YQSQVDLFNEQVKKCQVLEVQLNENKEKQQQLELQWN-NQKKEIEEQNNQVQFELKNKLS 1276

Query: 323  ELTKKIELLEHLNCQIRQTNKELENKLATMG---TESKAVSSPSKKGSPLISRK-----S 374
            EL K I    H   Q++   ++ +N+LA +     + +   +  KK +  +S K      
Sbjct: 1277 ELEKTIASQTHEEHQLKNDLEKYQNQLAQIAGQLNQKETQLNLFKKENSALSSKIQQIDE 1336

Query: 375  GRNTASK---MKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEK 431
              NT  +    K    +     L Q  DK++ + E  K E        DL+  E +   K
Sbjct: 1337 ENNTEKQELTQKIEKLEAQQAELQQKYDKQVKQYERVKKEKE----ENDLLADEEIHKLK 1392

Query: 432  DTXXXXXXXXXXGKD-------TLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQ 484
                         K+       T + +L+++  +H +  +      + + V  + K  E 
Sbjct: 1393 QNYEALLESEKAAKEDVKKEFITKVDELKIQVARH-DTKTRQTEDKHQKQVKTLEKEVES 1451

Query: 485  LKQELNDEIKDVNVKDLIEKLKSAEEQITQLN-----------DEIDAANKNMIKVKSNH 533
            LKQ  N +I+   +K + E  K  EE+  QL            DE+   N+  I+V +  
Sbjct: 1452 LKQLNNKKIE--TMKTIQETCKKLEEEKGQLESQYKKKEQKFIDELKEKNEE-IEVLTQQ 1508

Query: 534  KLKLKQMQ-----KTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEE--KGNLQLHLV 586
            K K+ ++Q     K I    KVS+ ++   +L +EL    +K   +E+E  + N Q  + 
Sbjct: 1509 KKKINEIQNELQEKLIAEQKKVSELSENQEKLAKELQQSEEKKISIEKEWIQKNQQT-IA 1567

Query: 587  DYDSGRMIESDV-YKKMI---------EMENLAETRLKAISLLESQKFDLVQELHILQQK 636
            +Y+S ++ E D  ++K++         +++ L+   +K       ++ +L  +++ LQ  
Sbjct: 1568 EYES-KISEKDAEFEKILSSKQGDSSQQIQELSSKNMKQEKEFREKENNLNNKINTLQSS 1626

Query: 637  YDEVEDKLADISQLQSDQVCSEI--KSVHLEEQIDALSASKKELALVIENLKLDKEQLYG 694
                E+KL  + + ++ ++ +++  K   L ++ID   AS KE    IE  + + ++   
Sbjct: 1627 VKNHEEKLKSLEE-ENSKLSTQLSEKIAVLNKEIDTHKASIKENQNQIEAFEKEIKEKNQ 1685

Query: 695  TIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGID 754
             IK+LE+DK D+  K     ++ + ++ +LE+  A K  E+  K++ +          I 
Sbjct: 1686 IIKNLESDKSDLEEKTLKQEEKIVLISTQLEQTKASK-KEIEDKLSRK----------IK 1734

Query: 755  AKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYS 814
             K  E+++  ++   ++  YK  I  L+ + +   D  +S + K  Q+ S + +     +
Sbjct: 1735 EKETEQNIISQDYNQKIQVYKQTIEHLQNN-SRQGDINFSQDLKFSQI-SKITDNLSDNN 1792

Query: 815  EYTIQEDELVNR--LAVLMDHDRVVEKQLLEIEH-ENKELQKKNQILLEENQNLQISLSD 871
             +  Q D+L  +     LM     + +    +    +KE  +     L +      ++  
Sbjct: 1793 SHDEQADKLSGKELSQRLMSGVAALSQSRASVSSIRSKEETRSMYKKLSQMSMATAAMMS 1852

Query: 872  MQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQ 915
            +++ Y +L E A   D  +  +T  Q    D++  L +   +H+
Sbjct: 1853 VKRDYVSLKELAKSIDDHDVNNTSNQ---EDIDPRLTKSEIQHK 1893


>UniRef50_A0DZ20 Cluster: Chromosome undetermined scaffold_7, whole
            genome shotgun sequence; n=2; Paramecium tetraurelia|Rep:
            Chromosome undetermined scaffold_7, whole genome shotgun
            sequence - Paramecium tetraurelia
          Length = 1760

 Score =  153 bits (371), Expect = 4e-35
 Identities = 229/1140 (20%), Positives = 513/1140 (45%), Gaps = 100/1140 (8%)

Query: 471  NTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLND-EIDAANKNMIKV 529
            N E  ++I + Q QL + L  EI+ + V      LK +E++  QL + +++  N++ I +
Sbjct: 116  NNEHQSQIKEYQNQL-ESLQSEIEKLQVS-----LKQSEQKQQQLQEVQLEQNNQHRIDI 169

Query: 530  KSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYD 589
            +S  + +L++ + T DN  +    ++  + L  +     +       E+ NL L ++  D
Sbjct: 170  ESLIE-RLQKSESTKDNLQQELQKHQNNLELIAKQKKEIESYKIQLSEQNNL-LDIIKSD 227

Query: 590  SGRMIES---DVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLAD 646
            +  ++++    + K+  + ++    +LK    LE Q  +  ++L  +Q +  ++  +L+ 
Sbjct: 228  NKIIVQNLAEQLKKEEQKTKDANNEKLKLEQSLERQLNEKNEQLKKVQNEIHQLNQELS- 286

Query: 647  ISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDI 706
             SQ Q +Q    IKS  L+EQI+ +++  K+L    +++    EQ    ++  E     I
Sbjct: 287  -SQEQKNQKI--IKS--LDEQIEKVNSEIKDLKQKSQHINNINEQQTIKLQQQEEIISQI 341

Query: 707  MNKLQNY---IQENMDLTDKLEKMSAEKI---SELLAKINHEEQSKIQTQFGI---DAKI 757
            +N+   +   ++E  +L  KL++   ++I   S    K    ++ K   +  I   ++KI
Sbjct: 342  INENSQFKGQVEEQQNLVIKLKEQCQKEIEQKSHFDKKYLDLQEEKENAELRINQLESKI 401

Query: 758  QERDLYIENIES----ELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAY 813
             E+    + IES    ++  +++ I  L + +  +ED++ S E K  +  + LQ++ +  
Sbjct: 402  LEQQNEQKQIESNTFQDIQNFQNTIQSLNQKL--IEDKQNS-EDKIQEFNNLLQQQMQNN 458

Query: 814  SEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQ 873
               + Q+D+L +++  L   +    KQ+ +   +  +L+K+ Q L   NQ  +     + 
Sbjct: 459  QLMSKQQDDLKSQIEQLNIQNEDQGKQIYQNSQQILDLEKQIQDLKIINQQSKDQNEQLI 518

Query: 874  QHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFN 933
            Q  +  + KA              TQ   ++  LK+  ++ + +I Q +K+   L++E  
Sbjct: 519  QQIDDNISKA--------------TQETGVQEQLKQKLNQSEDIIEQLQKDKSQLQLELE 564

Query: 934  TQIESAIRDKKVLNEKYEKNIEYVT----QLEAQLQEYKNNIENLNMNVEELNKMNLELI 989
               E +  +K  + ++     E +T    +++ Q+QE +  I NL +++EE ++   +L 
Sbjct: 565  QLKEGSNLEKVQILQELSNAKEEITSSDEKIKKQIQEKEEMITNLRLDIEEKSQQTSQLQ 624

Query: 990  DK--HVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYE 1047
            D+  ++Q +  QS     + + ++  L   + ++ + I  L Q           + S ++
Sbjct: 625  DESNNIQSKLQQSEQKYSELLKQVEILTLQIHEQQDTIKQLEQ-----------IKSSFQ 673

Query: 1048 SKLAQFTTKLENMEEEMQRVS-KQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNI 1106
            ++L  +T  +     ++++VS K   ++K  ++E+Q L +   DQ + L E +L      
Sbjct: 674  NQLLIWTETINQKMSDLEQVSQKNDSNTKLLSQEIQALTQRSKDQ-ELLSEAQLEMASQN 732

Query: 1107 PKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQ---EEEEFIQERSVLQEQSAK 1163
              ++   I    + + +   +++            L+ +   E +E +Q +  +Q+    
Sbjct: 733  ESSKDKNIEQLQQELKETIASLESNKQKYEAQYIALQEKLSLEYDELLQNKLNIQKLQLS 792

Query: 1164 LNTELQEC-YTKIIQLET---LNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAE 1219
               + Q+C  T  IQ++    L+ +       +QE+ N + S  +++   N+ +   ++E
Sbjct: 793  NQYDQQKCEITNEIQIQKQLFLDCQQELQQFKDQEKFN-MNSYQKEIEDLNELIHKQMSE 851

Query: 1220 LRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSS- 1278
             +  +   ++Q   ++ EL  ++L Q     Q +    + Q +A   ++++ +D  +S  
Sbjct: 852  -KQILIEELEQIQIKLKEL--ENLKQENETLQNSVRIEQEQKNAMIQQFQKEIDIQKSQI 908

Query: 1279 TQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXX 1338
             +E+ N   +++++  LQ ++QD    L N QE+    + Q++I   +++++++      
Sbjct: 909  IEEQKNNEQSLDKINQLQQQIQD----LINKQEQVNIDLEQMKISLKQVQEKELKLVSDF 964

Query: 1339 XXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDA 1398
                        +L T+ Q  KQ ++Q    I +   Q+   +              N  
Sbjct: 965  NYQSVLLEETQLNLDTKVQYIKQQEQQYSAEIQQLKDQILGLNNQNLQLEQQILQLQN-- 1022

Query: 1399 EAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESE 1458
               V+EL       +S+I Q+      TL Q  ++FE       E +KRI+D     + +
Sbjct: 1023 -GHVIELEQNSRDVESKINQENQN---TLIQLRNDFETAAMAFQEQKKRIQDENDAFQVQ 1078

Query: 1459 LAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAK 1518
            +  L +K     N  +  Q + ++ER +  EE   ++T       +  E+ ++L++   +
Sbjct: 1079 IEELVIK-----NLEQKQQSQEQLERKQ--EEYQQEVTLLKRQRMEQDEMIQSLQKSQVQ 1131

Query: 1519 TNEMQTALENQEIEIVTLNDEITNLQNMVRAS-SSKIQKHVSFASDTK---QGRDEQLDN 1574
              E +  L+   I +  + +E+  ++     +  S+ QKH S   D     Q   +QL+N
Sbjct: 1132 LKEKENQLDQLNISLSIIQEELYQMEQKYENNLLSQKQKHESQIEDLHRLIQELKQQLNN 1191



 Score =  148 bits (358), Expect = 1e-33
 Identities = 182/893 (20%), Positives = 389/893 (43%), Gaps = 77/893 (8%)

Query: 701  NDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQER 760
            N KED+ N +Q      +D   +  K++ E I     K  +++  +I+    +   +Q  
Sbjct: 24   NQKEDLTNDIQQIENNELDEQPRAHKIAEESI----VKNENDDNQQIKQ---LQENLQHS 76

Query: 761  DLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQE 820
             L +EN    + KYK+  C+  E+    + +  SL+ + D   +  Q + K Y       
Sbjct: 77   HLELENY---IQKYKALECQFSEAQTFQQKQIESLQGQFDHQNNEHQSQIKEYQNQLESL 133

Query: 821  DELVNRLAVLMDHDRVVEKQLLEIE-HENKELQKKNQILLEENQNLQISLSDMQQHYNAL 879
               + +L V +      ++QL E++  +N + +   + L+E  Q  + +  ++QQ     
Sbjct: 134  QSEIEKLQVSLKQSEQKQQQLQEVQLEQNNQHRIDIESLIERLQKSESTKDNLQQELQKH 193

Query: 880  VEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESA 939
                      + E   Y+ QL + ++NL  I      +IVQ     E L+ E   + + A
Sbjct: 194  QNNLELIAKQKKEIESYKIQLSE-QNNLLDIIKSDNKIIVQNL--AEQLKKE-EQKTKDA 249

Query: 940  IRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNV---EELNKMNLELIDKHVQKQ 996
              +K  L +  E+ +    +   QL++ +N I  LN  +   E+ N+  ++ +D+ ++K 
Sbjct: 250  NNEKLKLEQSLERQL---NEKNEQLKKVQNEIHQLNQELSSQEQKNQKIIKSLDEQIEKV 306

Query: 997  QTQSPDYTE--QYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFT 1054
             ++  D  +  Q+IN IN+   +  Q+ EEII+   +I N    +   V + ++ + +  
Sbjct: 307  NSEIKDLKQKSQHINNINEQQTIKLQQQEEIIS---QIINENSQFKGQVEEQQNLVIKLK 363

Query: 1055 TKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMN----IPKTE 1110
             + +   E+     K+ LD ++  E  ++ + + + +I E +  +   E N    I   +
Sbjct: 364  EQCQKEIEQKSHFDKKYLDLQEEKENAELRINQLESKILEQQNEQKQIESNTFQDIQNFQ 423

Query: 1111 GMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQ- 1169
              I S   + + D  N+ D             ++Q  +   +++  L+ Q  +LN + + 
Sbjct: 424  NTIQSLNQKLIEDKQNSEDKIQEFNNLLQQ--QMQNNQLMSKQQDDLKSQIEQLNIQNED 481

Query: 1170 ---ECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISS 1226
               + Y    Q+  L  ++    ++NQ+  +Q +  ++Q++ +N +  +    ++  +  
Sbjct: 482  QGKQIYQNSQQILDLEKQIQDLKIINQQSKDQNEQLIQQID-DNISKATQETGVQEQLKQ 540

Query: 1227 AVDQRGFEIAELWKQ------HLAQRE--ADFQKTE--HELRVQLSAFESKYEQLLDSVQ 1276
             ++Q    I +L K        L Q +  ++ +K +   EL        S  E++   +Q
Sbjct: 541  KLNQSEDIIEQLQKDKSQLQLELEQLKEGSNLEKVQILQELSNAKEEITSSDEKIKKQIQ 600

Query: 1277 SSTQEETNKIVTMEQVTSLQNKLQDK----EEHLRNLQEKYADVINQIEILRSEIEDEKV 1332
               +  TN  + +E+ +   ++LQD+    +  L+  ++KY++++ Q+EIL  +I +++ 
Sbjct: 601  EKEEMITNLRLDIEEKSQQTSQLQDESNNIQSKLQQSEQKYSELLKQVEILTLQIHEQQD 660

Query: 1333 AFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXX 1392
                                 T NQ    +++ S    N+ N +L               
Sbjct: 661  TIKQLEQIKSSFQNQLLIWTETINQKMSDLEQVS--QKNDSNTKLLSQEIQALTQRSKDQ 718

Query: 1393 XRVNDAEAKVLELTHQLE-LKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDL 1451
              +++A+   LE+  Q E  KD  I Q   E   T+       +    Q +  ++++  L
Sbjct: 719  ELLSEAQ---LEMASQNESSKDKNIEQLQQELKETIASLESNKQKYEAQYIALQEKL-SL 774

Query: 1452 TYEK--ESELAILRLKMHENANHYETMQKE--SEIERVKLI-----EEL-NVKITESVSL 1501
             Y++  +++L I +L++   +N Y+  + E  +EI+  K +     +EL   K  E  ++
Sbjct: 775  EYDELLQNKLNIQKLQL---SNQYDQQKCEITNEIQIQKQLFLDCQQELQQFKDQEKFNM 831

Query: 1502 N---KQVAELNKALEEEVAKTNEMQTALENQEI---EIVTLNDEITNLQNMVR 1548
            N   K++ +LN+ + +++++   +   LE  +I   E+  L  E   LQN VR
Sbjct: 832  NSYQKEIEDLNELIHKQMSEKQILIEELEQIQIKLKELENLKQENETLQNSVR 884



 Score =  136 bits (329), Expect = 5e-30
 Identities = 270/1325 (20%), Positives = 564/1325 (42%), Gaps = 109/1325 (8%)

Query: 218  MTKMQENFIAMEAEWKDEKQRLLKDIE---SKDVRISSLEEA--NKLLEAARFEISLEHS 272
            + K  ++   +  + KD+ ++L++ I+   SK  + + ++E    KL ++      L+  
Sbjct: 496  LEKQIQDLKIINQQSKDQNEQLIQQIDDNISKATQETGVQEQLKQKLNQSEDIIEQLQKD 555

Query: 273  KLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIEL-L 331
            K   +LE               L  Q +  + EE T  +EK   +I    E+   + L +
Sbjct: 556  KSQLQLELEQLKEGSNLEKVQIL--QELSNAKEEITSSDEKIKKQIQEKEEMITNLRLDI 613

Query: 332  EHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASK----MKSPWS 387
            E  + Q  Q   E  N  + +    +  S   K+   L  +   +    K    +KS + 
Sbjct: 614  EEKSQQTSQLQDESNNIQSKLQQSEQKYSELLKQVEILTLQIHEQQDTIKQLEQIKSSFQ 673

Query: 388  Q---LSSETLNQ---DTDKKINKNE--IAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXX 439
                + +ET+NQ   D ++   KN+     L   IQ+L +   D+E ++SE         
Sbjct: 674  NQLLIWTETINQKMSDLEQVSQKNDSNTKLLSQEIQALTQRSKDQE-LLSEAQLEMASQN 732

Query: 440  XXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKD-VNV 498
                 KD  I QLQ   Q+  E  + +       +   IA +QE+L  E ++ +++ +N+
Sbjct: 733  ESS--KDKNIEQLQ---QELKETIASLESNKQKYEAQYIA-LQEKLSLEYDELLQNKLNI 786

Query: 499  KDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIV 558
            + L +     ++Q  ++ +EI    +  +  +     +L+Q  K  + F+ ++   KEI 
Sbjct: 787  QKL-QLSNQYDQQKCEITNEIQIQKQLFLDCQQ----ELQQF-KDQEKFN-MNSYQKEIE 839

Query: 559  RLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRL--KAI 616
             L E +H    +   L EE   +Q+ L + ++ +  E++  +  + +E   +  +  +  
Sbjct: 840  DLNELIHKQMSEKQILIEELEQIQIKLKELENLKQ-ENETLQNSVRIEQEQKNAMIQQFQ 898

Query: 617  SLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEE-QIDALSASK 675
              ++ QK  +++E    +Q  D++      I  L + Q   E  ++ LE+ +I      +
Sbjct: 899  KEIDIQKSQIIEEQKNNEQSLDKINQLQQQIQDLINKQ---EQVNIDLEQMKISLKQVQE 955

Query: 676  KELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKIS-- 733
            KEL LV  +       L  T  +L+   + I  + Q Y  E   L D++  ++ + +   
Sbjct: 956  KELKLV-SDFNYQSVLLEETQLNLDTKVQYIKQQEQQYSAEIQQLKDQILGLNNQNLQLE 1014

Query: 734  -ELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESEL-SKYKSRICRLEESIAVMEDR 791
             ++L   N       Q    +++KI + +   +N   +L + +++     +E    ++D 
Sbjct: 1015 QQILQLQNGHVIELEQNSRDVESKINQEN---QNTLIQLRNDFETAAMAFQEQKKRIQDE 1071

Query: 792  RYSLERKADQLG-SYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKE 850
              + + + ++L    L++KQ++  +   +++E    + +L       ++Q +E +   + 
Sbjct: 1072 NDAFQVQIEELVIKNLEQKQQSQEQLERKQEEYQQEVTLL-------KRQRMEQDEMIQS 1124

Query: 851  LQKKNQILLEENQN----LQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESN 906
            LQK +Q+ L+E +N    L ISLS +Q+    + +K     L++ +  K+++Q+ DL   
Sbjct: 1125 LQK-SQVQLKEKENQLDQLNISLSIIQEELYQMEQKYENNLLSQKQ--KHESQIEDLH-- 1179

Query: 907  LKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQE 966
              R+  E +  +   + E   ++   N       + K++  E  E  I+ V +L+ Q  +
Sbjct: 1180 --RLIQELKQQLNNVESEGRMMQNSLNEMEVLDFKCKELKTENEELKIK-VQELQTQPNQ 1236

Query: 967  YKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEII 1026
             K   ++ N N        ++ ++  + KQ+ +  +  +Q   E  +LN  +     EI 
Sbjct: 1237 QKGEFQSYNHNNNNEESDQIKELNSEILKQKQEHFEIQQQLTQEKEQLNDQIAVLKGEIQ 1296

Query: 1027 ALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDS--KQHN---EEL 1081
               + I   Q    S+    ++K +Q ++ L N    +Q  S Q   +  KQ+N   +E 
Sbjct: 1297 EQKKLIIQQQAQIQSLTQQQQAKQSQESSNLINFNPYLQNHSYQQAQTGDKQNNIPQKEY 1356

Query: 1082 QILVREQDDQIKELKETKLTFEMNIPKTEGMIISST-IEPMSDDANNVDXXXXXXXXXXX 1140
            QIL ++  +Q  +++  +L+ E+   K++    +    + +S ++ +++           
Sbjct: 1357 QILEKKSKEQ--QIQIQQLSNELAALKSQQEDKAKVQNQKLSRNSTSMETIVEKCAALQQ 1414

Query: 1141 XLKVQE--EEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQ 1198
             +  Q     +   E  + ++Q+ +L  +++ C+ ++ +L  ++ +      +  E    
Sbjct: 1415 IIDEQSIINSKLNVEIGLFKQQNEQLKEDIKVCHQELKELRIISQDKFR---LESELQQA 1471

Query: 1199 LKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELR 1258
            L    EQ NT+ND++     +L   +     ++  E+  L KQ     E   QK + +L 
Sbjct: 1472 LALIAEQHNTQNDSI--QFKQLTQELQEKNKKQSEELESLKKQQ-KLIEKQKQKIQEKLN 1528

Query: 1259 VQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVIN 1318
              +   E K ++LL   Q    ++  KI+ +E++  LQ++LQD       L+ +Y D I 
Sbjct: 1529 DAIEELE-KLKKLLQISQQEQDQKNTKIIELERL--LQSQLQD----FSILEGQYKDSIK 1581

Query: 1319 QIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLK 1378
              EI++ ++++  +                  D + + Q   QMQ      I E +AQ  
Sbjct: 1582 NYEIIKQQLDELNI-------KSMREIDELNKDNQQKEQRIIQMQGDLQNLIKEVHAQKD 1634

Query: 1379 KSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVR 1438
              +            +       +     +LE+ +  +  +     I LT   +E  +  
Sbjct: 1635 FQARQKQVSSAPLTKKDKIVVESLANRVQELEMLNKTLKDQLSGKIIKLTNELEEKVSYI 1694

Query: 1439 QQLV-EYEKRIEDLT----YEKESELAILRLKMHENANHY--ETMQKESEI-ERVKLI-E 1489
            Q L   + K   +LT     EKE    I +LK  +N       TM +  ++ E++KL+  
Sbjct: 1695 QLLAYHFSKAYPNLTEADIIEKEDVKLIQQLKKKQNIQEIIERTMIENLQLREQIKLLGA 1754

Query: 1490 ELNVK 1494
            ELN K
Sbjct: 1755 ELNKK 1759



 Score =  102 bits (244), Expect = 9e-20
 Identities = 142/793 (17%), Positives = 332/793 (41%), Gaps = 65/793 (8%)

Query: 834  DRVVEKQLLEI-EHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESE 892
            D +VE+Q     E++N++ +  NQ     N   QI  +++ +   A   K     + ++E
Sbjct: 2    DNLVEEQNSTYNEYDNQQTEVINQKEDLTNDIQQIENNELDEQPRA--HKIAEESIVKNE 59

Query: 893  STKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEK 952
            +   Q Q++ L+ NL+  +H      +QK K +E    E  T  +  I  + +  +   +
Sbjct: 60   NDDNQ-QIKQLQENLQH-SHLELENYIQKYKALECQFSEAQTFQQKQI--ESLQGQFDHQ 115

Query: 953  NIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEIN 1012
            N E+    ++Q++EY+N +E+L   +E+L +++L+  ++  Q+ Q    +   Q+  +I 
Sbjct: 116  NNEH----QSQIKEYQNQLESLQSEIEKL-QVSLKQSEQKQQQLQEVQLEQNNQHRIDIE 170

Query: 1013 KLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLL 1072
             L   L++ +     L Q++   Q + + +++  + ++  +  +L      +  +     
Sbjct: 171  SLIERLQKSESTKDNLQQELQKHQ-NNLELIAKQKKEIESYKIQLSEQNNLLDIIKS--- 226

Query: 1073 DSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXX 1132
            D+K   + L   +++++ + K+    KL  E ++ +     ++   E +    N +    
Sbjct: 227  DNKIIVQNLAEQLKKEEQKTKDANNEKLKLEQSLERQ----LNEKNEQLKKVQNEIHQLN 282

Query: 1133 XXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVN 1192
                      + Q+ ++ I+    L EQ  K+N+E+++   K   +  +N + T      
Sbjct: 283  QELSS-----QEQKNQKIIKS---LDEQIEKVNSEIKDLKQKSQHINNINEQQTIKLQQQ 334

Query: 1193 QEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQK 1252
            +E I+Q+ ++  Q   + +   + V +L+      ++Q+     +       +  A+ + 
Sbjct: 335  EEIISQIINENSQFKGQVEEQQNLVIKLKEQCQKEIEQKSHFDKKYLDLQEEKENAELRI 394

Query: 1253 TEHELRV-----QLSAFESKYEQLLDSVQSSTQEETNKIVTMEQ-----VTSLQNKLQDK 1302
             + E ++     +    ES   Q + + Q++ Q    K++  +Q     +    N LQ +
Sbjct: 395  NQLESKILEQQNEQKQIESNTFQDIQNFQNTIQSLNQKLIEDKQNSEDKIQEFNNLLQQQ 454

Query: 1303 EEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQM 1362
             ++ + + ++  D+ +QIE L  + ED+                    DL+  NQ  K  
Sbjct: 455  MQNNQLMSKQQDDLKSQIEQLNIQNEDQGKQIYQNSQQILDLEKQIQ-DLKIINQQSKDQ 513

Query: 1363 QEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHE 1422
             EQ I  I++  ++  + +            ++N +E  + +L         E+ Q    
Sbjct: 514  NEQLIQQIDDNISKATQETGVQEQLKQ----KLNQSEDIIEQLQKDKSQLQLELEQLKEG 569

Query: 1423 YTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESE- 1481
              +   Q   E  N ++++   +++I+    EKE  +  LRL + E +     +Q ES  
Sbjct: 570  SNLEKVQILQELSNAKEEITSSDEKIKKQIQEKEEMITNLRLDIEEKSQQTSQLQDESNN 629

Query: 1482 ------------IERVKLIEELNVKITESVSLNKQVAELNKALEEEV--------AKTNE 1521
                         E +K +E L ++I E     KQ+ ++  + + ++         K ++
Sbjct: 630  IQSKLQQSEQKYSELLKQVEILTLQIHEQQDTIKQLEQIKSSFQNQLLIWTETINQKMSD 689

Query: 1522 MQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELL 1581
            ++   +  +     L+ EI  L    +      +  +  AS  +  +D+ ++  + +EL 
Sbjct: 690  LEQVSQKNDSNTKLLSQEIQALTQRSKDQELLSEAQLEMASQNESSKDKNIEQ-LQQELK 748

Query: 1582 DAVPRAELDLAMY 1594
            + +   E +   Y
Sbjct: 749  ETIASLESNKQKY 761



 Score = 66.5 bits (155), Expect = 6e-09
 Identities = 130/668 (19%), Positives = 273/668 (40%), Gaps = 60/668 (8%)

Query: 151  IKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXX 210
            +++K  +   L+ K +  +  +  L+ +  E+D++I++  K+                  
Sbjct: 1087 LEQKQQSQEQLERKQEEYQQEVTLLKRQRMEQDEMIQSLQKSQVQLKEKENQLDQLNISL 1146

Query: 211  X---EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEI 267
                E+  Q   K + N ++ + + + + + L + I+    +++++E   ++++ +  E+
Sbjct: 1147 SIIQEELYQMEQKYENNLLSQKQKHESQIEDLHRLIQELKQQLNNVESEGRMMQNSLNEM 1206

Query: 268  SLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIE-PSCEEKTEIEEKGSLEIANMTELTK 326
             +   K  +   +                +Q  E  S       EE   ++  N   L +
Sbjct: 1207 EVLDFKCKELKTENEELKIKVQELQTQPNQQKGEFQSYNHNNNNEESDQIKELNSEILKQ 1266

Query: 327  KIELLEHLNCQIRQTNKELENKLATMGTE----SKAVSSPSKKGSPLISRKSGRNTASKM 382
            K E  E +  Q+ Q  ++L +++A +  E     K +     +   L  ++  + +    
Sbjct: 1267 KQEHFE-IQQQLTQEKEQLNDQIAVLKGEIQEQKKLIIQQQAQIQSLTQQQQAKQSQESS 1325

Query: 383  K----SPWSQLSSETLNQDTDKKIN--KNEIAKLE-------MVIQSLNKDLVDKEYVIS 429
                 +P+ Q  S    Q  DK+ N  + E   LE       + IQ L+ +L   +    
Sbjct: 1326 NLINFNPYLQNHSYQQAQTGDKQNNIPQKEYQILEKKSKEQQIQIQQLSNELAALKSQQE 1385

Query: 430  EKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQEL 489
            +K                 I +     QQ ++  S+I+   N E +    +  EQLK+++
Sbjct: 1386 DKAKVQNQKLSRNSTSMETIVEKCAALQQIIDEQSIINSKLNVE-IGLFKQQNEQLKEDI 1444

Query: 490  ---NDEIKDVNVKDLIE-KLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTID 545
               + E+K++ +    + +L+S  +Q   L  E      + I+ K   +   ++ +K  +
Sbjct: 1445 KVCHQELKELRIISQDKFRLESELQQALALIAEQHNTQNDSIQFKQLTQELQEKNKKQSE 1504

Query: 546  NFSKVSDSNKEIVRLTEELHH-LSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIE 604
                +    K I +  +++   L+  + ELE+ K  LQ+   + D           K+IE
Sbjct: 1505 ELESLKKQQKLIEKQKQKIQEKLNDAIEELEKLKKLLQISQQEQDQKNT-------KIIE 1557

Query: 605  MENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDK-LADISQLQSDQVCSE----- 658
            +E L +++L+  S+LE Q  D ++   I++Q+ DE+  K + +I +L  D    E     
Sbjct: 1558 LERLLQSQLQDFSILEGQYKDSIKNYEIIKQQLDELNIKSMREIDELNKDNQQKEQRIIQ 1617

Query: 659  --------IKSVHL-------EEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDK 703
                    IK VH        ++Q+ +   +KK+  +V+E+L    ++L    K L++  
Sbjct: 1618 MQGDLQNLIKEVHAQKDFQARQKQVSSAPLTKKD-KIVVESLANRVQELEMLNKTLKDQL 1676

Query: 704  EDIMNKLQNYIQENMDLTDKLEKMSAEKISELL-AKINHEEQSKIQTQFGIDAKIQE--R 760
               + KL N ++E +     L    ++    L  A I  +E  K+  Q      IQE   
Sbjct: 1677 SGKIIKLTNELEEKVSYIQLLAYHFSKAYPNLTEADIIEKEDVKLIQQLKKKQNIQEIIE 1736

Query: 761  DLYIENIE 768
               IEN++
Sbjct: 1737 RTMIENLQ 1744


>UniRef50_A0CWC7 Cluster: Chromosome undetermined scaffold_3, whole
            genome shotgun sequence; n=1; Paramecium tetraurelia|Rep:
            Chromosome undetermined scaffold_3, whole genome shotgun
            sequence - Paramecium tetraurelia
          Length = 1425

 Score =  153 bits (371), Expect = 4e-35
 Identities = 234/1197 (19%), Positives = 513/1197 (42%), Gaps = 93/1197 (7%)

Query: 445  KDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKV-QEQLKQELNDEIKDVNVKDLIE 503
            K  L   LQL+ Q+ ++    +  GT  +D  +  +V  ++L++ +  + K+ + KD   
Sbjct: 208  KQELEQNLQLKQQECLQLQQKL--GTAEDDFRKKQQVILDELQKTIESKTKENSSKD--S 263

Query: 504  KLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNK---EIVRL 560
            K++  +E +  L+++I   +  + +V+   + ++  + K  +    + D +K   E+  L
Sbjct: 264  KIQDLQENLVLLSEQIKEKDLKIREVQEAEQKEISDIAK--ERIKLIGDLHKCQAELQEL 321

Query: 561  TEELHHLSQKVAELEEEKGNLQ-LHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLL 619
             +       ++ +L  +   +Q L  ++ D  + +  +   K+ E ++  E     I+ L
Sbjct: 322  QKTNAQQFSQIQQLTNKATQIQNLSKLEIDKLKQLNQEQQDKLQENQSNIELMNNKINEL 381

Query: 620  ESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVH-LEEQIDALSASKKEL 678
                  L Q+   L +  +++E +L    +    ++    + +H L+ QI      + +L
Sbjct: 382  TELNDQLNQQCDQLLKNKEQLEKELVQSKRDVEIELKQNQEFIHELQYQIQNHKNEQLQL 441

Query: 679  ALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAK 738
                +N + +  Q    + +L    + + N+ Q  I++N  L ++      +K  +    
Sbjct: 442  ESKFQNEQFELNQ---QLTNLNEQLQSLTNENQQLIKDNSLLNNEYTGYKKDKDQQ---- 494

Query: 739  INHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERK 798
            I+   Q   Q    +D   Q+ +L  + IE    KY  +I  L  +I  +ED++ SL +K
Sbjct: 495  IDQLNQLNNQLNNDLDQARQQFNLSQQEIEQ---KYSDQIQNLNSTITQLEDQKQSLLKK 551

Query: 799  ADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQ-LLEIEHENKELQKKNQI 857
            A++    LQ+    + +    E ++  +  +   ++    K  LL+ +   ++L  K  I
Sbjct: 552  ANEEKLQLQKIIATHQQELSLEKDINKQNEIKFTNEISQHKDDLLQKQMLIQQLNDKVHI 611

Query: 858  LLEENQNLQISLSDMQQHYNALVEKANR--TDLAESESTKYQTQLRDLESNLKRITHEHQ 915
            L E +++ + ++S     Y  L+++ N+  T L+E +  + + Q +  E + K    +++
Sbjct: 612  LQEHSKSQETNISKNIDDYKILLDQNNQQITQLSE-QIRQLKKQQKQQEQDSKTTISQYE 670

Query: 916  TLIVQKKKEIEDLEIEFNTQIESAIRDKKV-LNEKYEKNIEYVTQLEAQLQEYKNNIENL 974
              + Q  +E+   +I+ N   ES  + K+  L +  EK    ++Q    +Q+    I+ L
Sbjct: 671  LQMKQYLQELTQTKIQKN-DAESEKQSKEAQLTQVIEKQKSQLSQANTTIQDLNYQIQQL 729

Query: 975  NMNVEELNKMNLELIDK------HVQKQQTQSPDYTEQYINEI-------NKLNALLKQK 1021
              N+++ ++  L ++          + Q T      ++Y+NEI       ++L  LL+++
Sbjct: 730  QQNIKDQDEQRLSIVSSKQSAIYEKEHQITSLDSQVQKYLNEIQSKQEVISELQRLLEKQ 789

Query: 1022 DEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQL-LDSKQHNE- 1079
             +E+ +L  +    Q +    V + ++++     ++  ++  M +V  +  ++ +++N+ 
Sbjct: 790  KQEVTSLILERERTQKNSSQQVYELQAQIKDLNYEINQLKNSMVQVENEKNINKEEYNQA 849

Query: 1080 --ELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXX 1137
              +L+  +  Q   I EL+E    F  +  + E ++ +      S + N +         
Sbjct: 850  TDQLKEQINRQSTMIAELQE----FLKDSNQKE-LVSTQKATQQSLEINQLQLEFAKLKN 904

Query: 1138 XXXXLKVQEEEEFIQERSV-LQEQSAK----LNTELQECYTKIIQLETLNTELTGHDVVN 1192
                L +Q  +  I++  +  Q+Q  K     N   Q    KI  LE  + EL   ++  
Sbjct: 905  EQTLL-MQNNQSLIEDLQLKYQQQKQKDQDEYNKTSQVNLQKIQNLELESEELKNENLKL 963

Query: 1193 QEQINQLKSKLEQLNTENDNLLSTVAELRSS---ISSAVDQRGFEIAELWKQHLAQREAD 1249
            ++QI QL   + QL  E  N  + V +  S    + + ++++   I EL   +    +  
Sbjct: 964  KDQIEQLNQTINQLKDEYHNQNNLVQQTNSDQQRLQNEINEKSHRIEELELLN-ENSKTQ 1022

Query: 1250 FQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQV--TSLQNKLQDKEEHLR 1307
              +    +  QL   + +   + DS     Q   N+++   Q     L+N++  +  + +
Sbjct: 1023 IDQLNQTMLGQLEMIQFQKNNIQDS-----QIRYNQLLLENQEIQAKLENQILKENSYFK 1077

Query: 1308 NLQEKYADVINQIEILRSEIEDE--KVAFXXXXXXXXXXXXXXXXDLRTEN-QSYKQMQE 1364
             ++E       Q+E    +  DE  K+                   L TE    YK+  E
Sbjct: 1078 QIEELKVS-FEQLEQANLQQNDEIQKLQNQLEIENKKRENVEQEYKLVTEEFNDYKEQAE 1136

Query: 1365 QSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSE--------- 1415
            +SI  +       K  S            + ++ + K+ +L+ QL+ + S+         
Sbjct: 1137 KSINELQNTLISCKNESKQHINNTLLQQKQKSELDQKLAKLSQQLQSERSQFEFDLHQIQ 1196

Query: 1416 --IYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESEL-AILRLKMHENANH 1472
                QK  +  + + Q+ +E +  +QQL + EK +ED+ +E    L    ++K     + 
Sbjct: 1197 ENFNQKNKDLQLLINQKIEEIQKQQQQLKKQEK-LEDMIFELTIYLKKNQKIKFKRTKSL 1255

Query: 1473 YETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNE----MQTALE- 1527
             +T++K+ EI   +L +  N K+     + KQ++  N+    ++ K  E     Q  LE 
Sbjct: 1256 NQTLEKQLEINSSQLAQFQNEKLKLQTEI-KQLSNQNQQYLNQIQKYQEYIQQQQKDLEK 1314

Query: 1528 NQEI-EIVTLNDEITN-LQNMVRASSSKIQKHVSFASD-TKQGRDEQLDNTMNKELL 1581
            NQ I +   LND     L+  +     K+ + ++F  D     ++  L  T+N++L+
Sbjct: 1315 NQFINKTAVLNDNQGQILEKELTNLQKKLVQKLNFYKDLLSDKKNTDLKQTVNEDLI 1371



 Score =  133 bits (321), Expect = 4e-29
 Identities = 179/895 (20%), Positives = 378/895 (42%), Gaps = 65/895 (7%)

Query: 699  LENDKEDIMNKLQNYIQENMDLTDKL---EKMSAEKISELLAKINHEEQSKIQTQFGIDA 755
            +E  K+++   LQ   QE + L  KL   E    +K   +L ++    +SK +     D+
Sbjct: 204  IEARKQELEQNLQLKQQECLQLQQKLGTAEDDFRKKQQVILDELQKTIESKTKENSSKDS 263

Query: 756  KIQERDLYIENIESELSKYKSRICRLEES----IAVMEDRRYSLERKADQLGSYLQEKQK 811
            KIQ+    +  +  ++ +   +I  ++E+    I+ +   R  L     +  + LQE QK
Sbjct: 264  KIQDLQENLVLLSEQIKEKDLKIREVQEAEQKEISDIAKERIKLIGDLHKCQAELQELQK 323

Query: 812  AYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSD 871
              ++   Q  +L N+   + +  ++   +L ++  E ++  ++NQ  +E   N    L++
Sbjct: 324  TNAQQFSQIQQLTNKATQIQNLSKLEIDKLKQLNQEQQDKLQENQSNIELMNNKINELTE 383

Query: 872  MQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKR---ITHEHQTLIVQKKKEIEDL 928
            +    N   ++  +    + E    Q++ RD+E  LK+     HE Q  I   K E   L
Sbjct: 384  LNDQLNQQCDQLLKNK-EQLEKELVQSK-RDVEIELKQNQEFIHELQYQIQNHKNEQLQL 441

Query: 929  EIEFNTQIESAIRDKKVLNEKYE----KNIEYVTQLEAQLQEYKNNIENLNMNVEELNKM 984
            E +F  +     +    LNE+ +    +N + +        EY    ++ +  +++LN++
Sbjct: 442  ESKFQNEQFELNQQLTNLNEQLQSLTNENQQLIKDNSLLNNEYTGYKKDKDQQIDQLNQL 501

Query: 985  NLEL---IDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMS 1041
            N +L   +D+  Q+      +  ++Y ++I  LN+ + Q +++  +L +K N  ++    
Sbjct: 502  NNQLNNDLDQARQQFNLSQQEIEQKYSDQIQNLNSTITQLEDQKQSLLKKANEEKLQLQK 561

Query: 1042 MVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLT 1101
            +++ ++ +L+    K  N + E+ + + ++   K    + Q+L+++ +D++  L+E   +
Sbjct: 562  IIATHQQELS--LEKDINKQNEI-KFTNEISQHKDDLLQKQMLIQQLNDKVHILQEHSKS 618

Query: 1102 FEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQS 1161
             E NI K          + + D  N               LK Q++++    ++ + +  
Sbjct: 619  QETNISKN-----IDDYKILLDQNNQ---QITQLSEQIRQLKKQQKQQEQDSKTTISQYE 670

Query: 1162 AKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELR 1221
             ++   LQE     IQ     +E    +    + I + KS+L Q NT   +L   + +L+
Sbjct: 671  LQMKQYLQELTQTKIQKNDAESEKQSKEAQLTQVIEKQKSQLSQANTTIQDLNYQIQQLQ 730

Query: 1222 SSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYE---QLLDSVQSS 1278
             +I    +QR   I    +  + ++E      + +++  L+  +SK E   +L   ++  
Sbjct: 731  QNIKDQDEQR-LSIVSSKQSAIYEKEHQITSLDSQVQKYLNEIQSKQEVISELQRLLEKQ 789

Query: 1279 TQEETNKIVTME--------QVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDE 1330
             QE T+ I+  E        QV  LQ +++D    +  L+     V N+  I + E    
Sbjct: 790  KQEVTSLILERERTQKNSSQQVYELQAQIKDLNYEINQLKNSMVQVENEKNINKEEYNQA 849

Query: 1331 KVAFXXXXXXXXXXXXXXXXDLRTENQS---YKQMQEQSILNINEENAQLKKSSXXXXXX 1387
                                 L+  NQ      Q   Q  L IN+   +  K        
Sbjct: 850  TDQLKEQINRQSTMIAELQEFLKDSNQKELVSTQKATQQSLEINQLQLEFAKLKNEQTLL 909

Query: 1388 XXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRND-EFENVRQQLVEYEK 1446
                   + D + K      Q + KD + Y KT +  +   Q  + E E ++ + ++ + 
Sbjct: 910  MQNNQSLIEDLQLKY----QQQKQKDQDEYNKTSQVNLQKIQNLELESEELKNENLKLKD 965

Query: 1447 RIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVK-LIEELNVKITESVSLNK-- 1503
            +IE L         I +LK   +  +    Q  S+ +R++  I E + +I E   LN+  
Sbjct: 966  QIEQLNQ------TINQLKDEYHNQNNLVQQTNSDQQRLQNEINEKSHRIEELELLNENS 1019

Query: 1504 --QVAELNKALEEEVAKTNEMQTALENQEI---EIVTLNDEI-TNLQNMVRASSS 1552
              Q+ +LN+ +  ++      +  +++ +I   +++  N EI   L+N +   +S
Sbjct: 1020 KTQIDQLNQTMLGQLEMIQFQKNNIQDSQIRYNQLLLENQEIQAKLENQILKENS 1074



 Score =  128 bits (310), Expect = 9e-28
 Identities = 198/956 (20%), Positives = 424/956 (44%), Gaps = 96/956 (10%)

Query: 181  EKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLL 240
            +KDQ I+  N+                    ++ +Q+ +   +N  +   + +D+KQ LL
Sbjct: 490  DKDQQIDQLNQLNNQLNNDLDQARQQFNLSQQEIEQKYSDQIQNLNSTITQLEDQKQSLL 549

Query: 241  KDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSI 300
            K    + +++       K++   + E+SLE  K   +  +              L KQ +
Sbjct: 550  KKANEEKLQL------QKIIATHQQELSLE--KDINKQNEIKFTNEISQHKDDLLQKQML 601

Query: 301  EPSCEEKTEIEEKGSLEIANMTELTKKIE----LLEHLNCQIRQTN---KELENKLATMG 353
                 +K  I ++ S   +  T ++K I+    LL+  N QI Q +   ++L+ +     
Sbjct: 602  IQQLNDKVHILQEHSK--SQETNISKNIDDYKILLDQNNQQITQLSEQIRQLKKQQKQQE 659

Query: 354  TESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSET-LNQDTDKKINKNEIAKLEM 412
             +SK   S  +       ++  +    K  +   + S E  L Q  +K+  K+++++   
Sbjct: 660  QDSKTTISQYELQMKQYLQELTQTKIQKNDAESEKQSKEAQLTQVIEKQ--KSQLSQANT 717

Query: 413  VIQSLNKDLVDKEYVISEKD----TXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHV 468
             IQ LN  +   +  I ++D    +           K+  I  L  + Q+++       +
Sbjct: 718  TIQDLNYQIQQLQQNIKDQDEQRLSIVSSKQSAIYEKEHQITSLDSQVQKYLN-----EI 772

Query: 469  GTNTEDVNEIAKVQEQLKQELNDEI--KDVNVKDLIEKLKSAEEQITQLNDEIDAANKNM 526
             +  E ++E+ ++ E+ KQE+   I  ++   K+  +++   + QI  LN EI+    +M
Sbjct: 773  QSKQEVISELQRLLEKQKQEVTSLILERERTQKNSSQQVYELQAQIKDLNYEINQLKNSM 832

Query: 527  IKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEE-EKGNLQLHL 585
            ++V++   +  ++  +  D             +L E+++  S  +AEL+E  K + Q  L
Sbjct: 833  VQVENEKNINKEEYNQATD-------------QLKEQINRQSTMIAELQEFLKDSNQKEL 879

Query: 586  VDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHI-LQQKYDEVEDKL 644
            V          ++ +  +E   L   +    +LL      L+++L +  QQ+  + +D+ 
Sbjct: 880  VSTQKATQQSLEINQLQLEFAKLKNEQ----TLLMQNNQSLIEDLQLKYQQQKQKDQDEY 935

Query: 645  ADISQLQSDQVCS-EIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDK 703
               SQ+   ++ + E++S  L+ +   L    ++L   I  LK +       ++   +D+
Sbjct: 936  NKTSQVNLQKIQNLELESEELKNENLKLKDQIEQLNQTINQLKDEYHNQNNLVQQTNSDQ 995

Query: 704  EDIMNKL--QNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERD 761
            + + N++  +++  E ++L ++  K   +++++ +  +   E  + Q     D++I+   
Sbjct: 996  QRLQNEINEKSHRIEELELLNENSKTQIDQLNQTM--LGQLEMIQFQKNNIQDSQIRYNQ 1053

Query: 762  LYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQED 821
            L +EN E + +K +++I +       +E+ + S E+          E QK  ++  I+  
Sbjct: 1054 LLLENQEIQ-AKLENQILKENSYFKQIEELKVSFEQLEQANLQQNDEIQKLQNQLEIENK 1112

Query: 822  ELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISL-SDMQQHY-NAL 879
            +  N           VE++   +  E  + +++ +  + E QN  IS  ++ +QH  N L
Sbjct: 1113 KREN-----------VEQEYKLVTEEFNDYKEQAEKSINELQNTLISCKNESKQHINNTL 1161

Query: 880  VEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESA 939
            +++  +++L + +  K   QL+   S  +   H+ Q    QK K   DL++  N +IE  
Sbjct: 1162 LQQKQKSEL-DQKLAKLSQQLQSERSQFEFDLHQIQENFNQKNK---DLQLLINQKIEEI 1217

Query: 940  IRDKKVL--NEKYEKNIEYVTQLEAQLQEYK-NNIENLNMNVE---ELNKMNLELIDKHV 993
             + ++ L   EK E  I  +T    + Q+ K    ++LN  +E   E+N   L       
Sbjct: 1218 QKQQQQLKKQEKLEDMIFELTIYLKKNQKIKFKRTKSLNQTLEKQLEINSSQLAQFQNEK 1277

Query: 994  QKQQT---QSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKL 1050
             K QT   Q  +  +QY+N+I K    ++Q+ ++ +  NQ IN   V     ++D + ++
Sbjct: 1278 LKLQTEIKQLSNQNQQYLNQIQKYQEYIQQQQKD-LEKNQFINKTAV-----LNDNQGQI 1331

Query: 1051 AQFTTKLENMEEEM-QRVS--KQLLDSKQHNEELQILVREQDDQIKELKETKLTFE 1103
             +   +L N+++++ Q+++  K LL  K+ N +L+  V E  D I   K+  + FE
Sbjct: 1332 LE--KELTNLQKKLVQKLNFYKDLLSDKK-NTDLKQTVNE--DLITIKKDYIIAFE 1382



 Score =  109 bits (263), Expect = 5e-22
 Identities = 168/924 (18%), Positives = 400/924 (43%), Gaps = 68/924 (7%)

Query: 702  DKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERD 761
            +KE++ N+++ +I     +  K  K+                     +      K++ R 
Sbjct: 134  EKEELKNQIEYFIHIKQKVESKNSKVXXXXXXXXXXXXXXXXDFADDSPR--QGKLKARI 191

Query: 762  LYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGS--------YLQEKQKAY 813
               EN E +    ++R   LE+++ + +     L++K               L E QK  
Sbjct: 192  QRYENDEKQYIHIEARKQELEQNLQLKQQECLQLQQKLGTAEDDFRKKQQVILDELQKTI 251

Query: 814  SEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISL-SDM 872
               T +     +++  L ++  ++ +Q+ E + + +E+Q+  Q  + +    +I L  D+
Sbjct: 252  ESKTKENSSKDSKIQDLQENLVLLSEQIKEKDLKIREVQEAEQKEISDIAKERIKLIGDL 311

Query: 873  QQHYNAL--VEKANRTDLAE-SESTKYQTQLRDLE----SNLKRITHEHQTLIVQKKKEI 925
             +    L  ++K N    ++  + T   TQ+++L       LK++  E Q  + + +  I
Sbjct: 312  HKCQAELQELQKTNAQQFSQIQQLTNKATQIQNLSKLEIDKLKQLNQEQQDKLQENQSNI 371

Query: 926  EDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIE-NLNMNVEELNKM 984
            E +  + N   E  + D+  LN++ ++ ++   QLE +L + K ++E  L  N E ++++
Sbjct: 372  ELMNNKINELTE--LNDQ--LNQQCDQLLKNKEQLEKELVQSKRDVEIELKQNQEFIHEL 427

Query: 985  NLELIDKHVQKQQTQSPDYTEQY-----INEINKLNALLKQKDEEIIALNQKINNAQVSY 1039
              ++ +   ++ Q +S    EQ+     +  +N+    L  +++++I  N  +NN    Y
Sbjct: 428  QYQIQNHKNEQLQLESKFQNEQFELNQQLTNLNEQLQSLTNENQQLIKDNSLLNNEYTGY 487

Query: 1040 MSMVSDYESKLAQFTTKLEN-MEEEMQR--VSKQLLDSKQHNEELQILVREQDDQIKELK 1096
                     +L Q   +L N +++  Q+  +S+Q ++ K +++++Q L      Q+++ K
Sbjct: 488  KKDKDQQIDQLNQLNNQLNNDLDQARQQFNLSQQEIEQK-YSDQIQNL-NSTITQLEDQK 545

Query: 1097 ETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSV 1156
            ++ L  + N  K +   I +T +       +++               Q +++ +Q++ +
Sbjct: 546  QSLLK-KANEEKLQLQKIIATHQQELSLEKDINKQNEIKFTNEIS---QHKDDLLQKQML 601

Query: 1157 LQEQSAKLNTELQECYTKIIQLETLNTELTGHDVV---NQEQINQLKSKLEQLNTENDNL 1213
            +Q+ + K++  LQE ++K  Q   ++  +  + ++   N +QI QL  ++ QL  +    
Sbjct: 602  IQQLNDKVHI-LQE-HSK-SQETNISKNIDDYKILLDQNNQQITQLSEQIRQLKKQQK-- 656

Query: 1214 LSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLD 1273
                 + +++IS    Q    + EL +  + + +A+ +K   E   QL+    K +  L 
Sbjct: 657  -QQEQDSKTTISQYELQMKQYLQELTQTKIQKNDAESEKQSKE--AQLTQVIEKQKSQLS 713

Query: 1274 SVQSSTQEETNKIVTMEQ------------VTSLQNKLQDKEEHLRNLQEKYADVINQIE 1321
               ++ Q+   +I  ++Q            V+S Q+ + +KE  + +L  +    +N+I+
Sbjct: 714  QANTTIQDLNYQIQQLQQNIKDQDEQRLSIVSSKQSAIYEKEHQITSLDSQVQKYLNEIQ 773

Query: 1322 ILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSS 1381
              +  I + +                     +  +Q   ++Q Q I ++N E  QLK S 
Sbjct: 774  SKQEVISELQRLLEKQKQEVTSLILERERTQKNSSQQVYELQAQ-IKDLNYEINQLKNSM 832

Query: 1382 XXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQ---KTHEYTITLTQR-NDEFENV 1437
                          N A  ++ E  ++     +E+ +    +++  +  TQ+   +   +
Sbjct: 833  VQVENEKNINKEEYNQATDQLKEQINRQSTMIAELQEFLKDSNQKELVSTQKATQQSLEI 892

Query: 1438 RQQLVEYEKRIEDLTYEKESELAILR-LKMHENANHYETMQKESEIERVKLIEELNVKIT 1496
             Q  +E+ K   + T   ++  +++  L++       +   + ++  +V L +  N+++ 
Sbjct: 893  NQLQLEFAKLKNEQTLLMQNNQSLIEDLQLKYQQQKQKDQDEYNKTSQVNLQKIQNLEL- 951

Query: 1497 ESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQK 1556
            ES  L  +  +L   +E+     N+++    NQ   +   N +   LQN +   S +I++
Sbjct: 952  ESEELKNENLKLKDQIEQLNQTINQLKDEYHNQNNLVQQTNSDQQRLQNEINEKSHRIEE 1011

Query: 1557 HVSFASDTKQGRDEQLDNTMNKEL 1580
             +   ++  + + +QL+ TM  +L
Sbjct: 1012 -LELLNENSKTQIDQLNQTMLGQL 1034



 Score =  105 bits (251), Expect = 1e-20
 Identities = 154/782 (19%), Positives = 337/782 (43%), Gaps = 56/782 (7%)

Query: 838  EKQLLEIEHENKE----LQKKNQILLEENQNLQISLSDMQQHYNALVEKANRT-DLAESE 892
            EKQ + IE   +E    LQ K Q  L+  Q L  +  D ++    ++++  +T +    E
Sbjct: 198  EKQYIHIEARKQELEQNLQLKQQECLQLQQKLGTAEDDFRKKQQVILDELQKTIESKTKE 257

Query: 893  STKYQTQLRDLESNLKRITHE--HQTLIVQ-----KKKEIEDLEIEFNTQIESAIRDKKV 945
            ++   ++++DL+ NL  ++ +   + L ++     ++KEI D+  E    I    + +  
Sbjct: 258  NSSKDSKIQDLQENLVLLSEQIKEKDLKIREVQEAEQKEISDIAKERIKLIGDLHKCQAE 317

Query: 946  LNEKYEKNIEYVTQLEAQLQEYKNNIENLN-MNVEELNKMNLELIDKHVQKQQTQSPDYT 1004
            L E  + N +  +Q++ QL      I+NL+ + +++L ++N E  DK +Q+ Q+ + +  
Sbjct: 318  LQELQKTNAQQFSQIQ-QLTNKATQIQNLSKLEIDKLKQLNQEQQDK-LQENQS-NIELM 374

Query: 1005 EQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEM 1064
               INE+ +LN  L Q+ ++++   +++    V       D E +L Q    +  ++ ++
Sbjct: 375  NNKINELTELNDQLNQQCDQLLKNKEQLEKELV---QSKRDVEIELKQNQEFIHELQYQI 431

Query: 1065 Q-RVSKQL-LDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMS 1122
            Q   ++QL L+SK  NE+ ++   +Q   + E  ++       + K   ++ +       
Sbjct: 432  QNHKNEQLQLESKFQNEQFEL--NQQLTNLNEQLQSLTNENQQLIKDNSLLNNEYTGYKK 489

Query: 1123 DDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLN 1182
            D    +D            L  Q  ++F   +   QE   K + ++Q   + I QLE   
Sbjct: 490  DKDQQIDQLNQLNNQLNNDLD-QARQQFNLSQ---QEIEQKYSDQIQNLNSTITQLEDQK 545

Query: 1183 TELTGHDVVNQEQINQ-LKSKLEQLNTENDNLLSTVAELRSSISSAVD---QRGFEIAEL 1238
              L       + Q+ + + +  ++L+ E D       +  + IS   D   Q+   I +L
Sbjct: 546  QSLLKKANEEKLQLQKIIATHQQELSLEKDINKQNEIKFTNEISQHKDDLLQKQMLIQQL 605

Query: 1239 -WKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQN 1297
              K H+ Q  +  Q+T       +S     Y+ LLD       + + +I  +++    Q 
Sbjct: 606  NDKVHILQEHSKSQET------NISKNIDDYKILLDQNNQQITQLSEQIRQLKKQQKQQE 659

Query: 1298 KLQDKEEHLRNLQEK-YADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTEN 1356
            +          LQ K Y   + Q +I +++ E EK +                    T  
Sbjct: 660  QDSKTTISQYELQMKQYLQELTQTKIQKNDAESEKQSKEAQLTQVIEKQKSQLSQANTTI 719

Query: 1357 QSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKD--- 1413
            Q      +Q   NI +++ Q                 ++   +++V +  ++++ K    
Sbjct: 720  QDLNYQIQQLQQNIKDQDEQRLSIVSSKQSAIYEKEHQITSLDSQVQKYLNEIQSKQEVI 779

Query: 1414 SEIY----QKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYE-KESELAILRLKMHE 1468
            SE+     ++  E T  + +R    +N  QQ+ E + +I+DL YE  + + ++++++  +
Sbjct: 780  SELQRLLEKQKQEVTSLILERERTQKNSSQQVYELQAQIKDLNYEINQLKNSMVQVENEK 839

Query: 1469 NANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALEN 1528
            N N  E  Q   +++     E++N + T    L + + + N+  +E V+     Q +LE 
Sbjct: 840  NINKEEYNQATDQLK-----EQINRQSTMIAELQEFLKDSNQ--KELVSTQKATQQSLEI 892

Query: 1529 QEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAE 1588
             ++++     ++ N Q ++  ++  + + +      ++ +D+   N  ++  L  +   E
Sbjct: 893  NQLQLEFA--KLKNEQTLLMQNNQSLIEDLQLKYQQQKQKDQDEYNKTSQVNLQKIQNLE 950

Query: 1589 LD 1590
            L+
Sbjct: 951  LE 952


>UniRef50_A0DR95 Cluster: Chromosome undetermined scaffold_60, whole
            genome shotgun sequence; n=1; Paramecium tetraurelia|Rep:
            Chromosome undetermined scaffold_60, whole genome shotgun
            sequence - Paramecium tetraurelia
          Length = 1119

 Score =  153 bits (370), Expect = 5e-35
 Identities = 241/1105 (21%), Positives = 486/1105 (43%), Gaps = 94/1105 (8%)

Query: 502  IEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLT 561
            +E+L+S  +Q+ Q  D+ +  NKN   V      ++K +Q  +D  ++     +   +  
Sbjct: 15   VERLQSLTKQLNQDIDQANLQNKNSQAVIDQQSTEIKLLQTKLDCINRDQLELQNKYQSL 74

Query: 562  EELH-HLSQKVAELEEEKGNLQ--LHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISL 618
            E+ H H++  V ++   +  L+    LVD    R I+ D  +++++ + L +   KA   
Sbjct: 75   EQQHLHVTDLVNQITAGQITLEQLKDLVDELKNRSIQYDEIQELLQGQALHDVISKAEQF 134

Query: 619  LESQKFDLVQELHILQQKYDEVEDKL-ADISQLQSDQVCSEIKSVHLEEQIDALSASKKE 677
              + + ++ QEL    ++Y E+  KL  D+ + + D + ++    +LE+ I  L+     
Sbjct: 135  --TLQCNINQELRDQLEQYPEIVIKLNQDLDKYKQDIINNKSSIANLEQTIADLNQEIHI 192

Query: 678  LALVIENLKLDKEQLYGTIK-DLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKI--SE 734
            L  ++E  +         I+  LE    ++  KL    Q+N +L D++E+++  K+    
Sbjct: 193  LKQLLEQEQNKNSLNQSQIQLQLETQLNELRLKLSQTEQKNEELEDEVEQINFFKVQMES 252

Query: 735  LLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYS 794
             L +I  E    +  +  + +     + + +++  +L+   S+   L + I  +ED+   
Sbjct: 253  QLQEILKENNKIMVDKDKLASDNLSLNTHNDDLSDQLNLQTSQNQDLNKKILELEDQVRL 312

Query: 795  LERKAD-----QLGSYLQEKQ-KAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHEN 848
            L+ +       ++    Q+ Q ++Y+E    +D  +  L +     ++  +Q L  ++++
Sbjct: 313  LKNQLSEDNDLEIQIIRQDAQLQSYNERLQMQDNEIQDLNLNNAEQKLNYQQSLN-KYQD 371

Query: 849  KELQKKNQILLEENQNLQISLSD-MQQHYNALVEKANRTDLAESESTKYQTQLRDLESNL 907
              +QK ++I  +E Q  QI L D + +  N +    ++  +   E  + + Q +  +   
Sbjct: 372  ILIQKDHKI--QELQQTQIDLQDQISELQNQIANLRHQAQIDADEINQLKLQHQQFQGK- 428

Query: 908  KRITHEHQTLIVQKKKEIEDLEIEF-NTQIESAIRDKKVLNEKYEKNIEYVTQ-LEAQLQ 965
                    T+I+  + +I+  ++E  N  ++ +  +  +LN+K     +++ Q LE Q Q
Sbjct: 429  ---NDSSNTIIINFQNQIQQFKLEIQNHLLQISELESSILNQKQ----QFINQKLELQ-Q 480

Query: 966  EYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEI 1025
             Y+  IE L    +E NK   +  D+ +Q  + Q  +   Q  +E  +L  ++ +KD+E+
Sbjct: 481  HYQQIIEKL----QEENKSLQDQNDQQIQSLEEQG-NQILQLSSENQELQQIIDEKDQEL 535

Query: 1026 IALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILV 1085
              LN  +   Q  Y S     E+ L +   +L   +   Q+  K L       + L++ V
Sbjct: 536  DKLNLYVRKQQEIYESNTKKNEA-LEESNRELLFKQNSFQKTIKDLYTQL---DALKLEV 591

Query: 1086 REQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQ 1145
             E+D    +LK+ +L+ E  I K     ++ T   +     N+             L +Q
Sbjct: 592  NEKD----QLKQQRLSLEYEISK-----LNQTNADLLQQITNMKIEINNYQIQITNLNLQ 642

Query: 1146 EEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQ 1205
             +   I+ RS  QE ++  N +L+E +TKI Q ET+  +       N++QIN+ + +++Q
Sbjct: 643  IDNTEIELRSSYQENNSSEN-QLKELFTKIEQQETIINQ-------NEKQINEDEFRIQQ 694

Query: 1206 LNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFE 1265
            L    D L    A+ +       +Q  F I +L +  L++   D +K E+EL ++   F 
Sbjct: 695  L---LDELQKLNAKNKEYYKKFEEQEIF-IKQL-QAELSESSNDIKKLENELLLKEEEFN 749

Query: 1266 SKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRS 1325
                  LD   +    E N +   +       + ++ ++ + NL+ +Y  V+  +E L+ 
Sbjct: 750  E-----LDDDYNKIWNELNAVKNNQSNLDSNARSEELQQLVANLKSEYDLVLKDLEALKK 804

Query: 1326 EIED------EKVAFXXXXXXXXXXXXXXXXDLRTE---NQSYKQMQEQSILNINEENAQ 1376
            ++ D      +K                    L+ E   NQ   + Q+Q I    E++ Q
Sbjct: 805  QLIDKDSQLNQKAMLVDKFNVKVMNQTSELRSLKQEIENNQIVIENQQQRIAK-QEQHIQ 863

Query: 1377 LKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFEN 1436
                S            + N   ++V+EL  QL +  S++     E T  L Q+  E   
Sbjct: 864  DLLRSLESEKKSQQSQVKDNTDNSRVMEL-QQLNMNLSKVID---EKTQKLYQQEQEILI 919

Query: 1437 VRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVK-LIEELNVKI 1495
            + ++L E E  I  +    E +L  LRLK         T QK S I   + + +E   K 
Sbjct: 920  LNEKLRETENYIRGI----EFQLNELRLKYESQVQ--ITYQKSSIISTSEDITDEFQSKF 973

Query: 1496 TESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQ 1555
             +   L ++  +L +  + ++  TN   + LE  E +I  L+ EI+  +N  + S+ +I 
Sbjct: 974  QQ---LQQKYIQLQR--DYQILLTN--SSKLEEYENKIALLSLEISRYRNSSKKSTPQIN 1026

Query: 1556 KHVSFASDTKQGRDEQLDNTMNKEL 1580
            +  S ++ T +    +L +   +EL
Sbjct: 1027 RESSSSAKTSKFNLGELQSPYPEEL 1051



 Score =  124 bits (300), Expect = 2e-26
 Identities = 192/949 (20%), Positives = 416/949 (43%), Gaps = 107/949 (11%)

Query: 394  LNQDTDKKI-----NKNEIAKLEMVIQSLNKDL-VDKEYVISEKDTXXXXXXXXXXGKDT 447
            LNQD DK       NK+ IA LE  I  LN+++ + K+ +  E++             +T
Sbjct: 158  LNQDLDKYKQDIINNKSSIANLEQTIADLNQEIHILKQLLEQEQNKNSLNQSQIQLQLET 217

Query: 448  LIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKS 507
             + +L+L+  Q  +    +      ++V +I   + Q++ +L + +K+ N K +++K K 
Sbjct: 218  QLNELRLKLSQTEQKNEELE-----DEVEQINFFKVQMESQLQEILKENN-KIMVDKDKL 271

Query: 508  AEEQITQLNDEIDAANKNMIKVKSNHKLKLK------QMQKTIDNFSKVSDSNKEIVRLT 561
            A + ++      D +++  ++   N  L  K      Q++   +  S+ +D   +I+R  
Sbjct: 272  ASDNLSLNTHNDDLSDQLNLQTSQNQDLNKKILELEDQVRLLKNQLSEDNDLEIQIIRQD 331

Query: 562  EELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLES 621
             +L   ++++   + E  +L L+  +            +K+   ++L   + + I + + 
Sbjct: 332  AQLQSYNERLQMQDNEIQDLNLNNAE------------QKLNYQQSL--NKYQDILIQKD 377

Query: 622  QKFDLVQELHI-LQQKYDEVEDKLADI---SQLQSDQVCSEIKSVHLEEQIDALSASKKE 677
             K   +Q+  I LQ +  E+++++A++   +Q+ +D++ +++K  H  +Q    + S   
Sbjct: 378  HKIQELQQTQIDLQDQISELQNQIANLRHQAQIDADEI-NQLKLQH--QQFQGKNDSSNT 434

Query: 678  LALVIEN-LKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELL 736
            + +  +N ++  K ++   +  +   +  I+N+ Q +I + ++L    +++  EK+ E  
Sbjct: 435  IIINFQNQIQQFKLEIQNHLLQISELESSILNQKQQFINQKLELQQHYQQI-IEKLQEEN 493

Query: 737  AKINHEEQSKIQTQ-------FGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVME 789
              +  +   +IQ+          + ++ QE    I+  + EL K    + + +E      
Sbjct: 494  KSLQDQNDQQIQSLEEQGNQILQLSSENQELQQIIDEKDQELDKLNLYVRKQQEIYESNT 553

Query: 790  DRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENK 849
             +  +LE    +L       QK   +   Q D L  +L V  + D++ ++Q L +E+E  
Sbjct: 554  KKNEALEESNRELLFKQNSFQKTIKDLYTQLDAL--KLEV-NEKDQL-KQQRLSLEYEIS 609

Query: 850  ELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDL----AESESTKYQTQLRDLES 905
            +L + N  LL++  N++I +++ Q     L  + + T++    +  E+   + QL++L +
Sbjct: 610  KLNQTNADLLQQITNMKIEINNYQIQITNLNLQIDNTEIELRSSYQENNSSENQLKELFT 669

Query: 906  NLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIE----YVTQLE 961
             ++    + +T+I Q +K+I + E     Q+   ++     N++Y K  E    ++ QL+
Sbjct: 670  KIE----QQETIINQNEKQINEDEFRIQ-QLLDELQKLNAKNKEYYKKFEEQEIFIKQLQ 724

Query: 962  AQLQEYKNNIENLN----MNVEELN----------------KMNLELIDKHVQKQQTQS- 1000
            A+L E  N+I+ L     +  EE N                K N   +D + + ++ Q  
Sbjct: 725  AELSESSNDIKKLENELLLKEEEFNELDDDYNKIWNELNAVKNNQSNLDSNARSEELQQL 784

Query: 1001 -PDYTEQYINEINKLNALLKQKDEEIIALNQK---INNAQVSYMSMVSDYESKLAQFTTK 1056
              +   +Y   +  L AL KQ  ++   LNQK   ++   V  M+  S+  S   +    
Sbjct: 785  VANLKSEYDLVLKDLEALKKQLIDKDSQLNQKAMLVDKFNVKVMNQTSELRSLKQEIENN 844

Query: 1057 LENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISS 1116
               +E + QR++KQ    +     L+   + Q  Q+K+  +     E+   +   M +S 
Sbjct: 845  QIVIENQQQRIAKQEQHIQDLLRSLESEKKSQQSQVKDNTDNSRVMEL---QQLNMNLSK 901

Query: 1117 TIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQE-RSVLQEQSAKLNTELQECYTKI 1175
             I+  +      +             K++E E +I+     L E   K  +++Q  Y K 
Sbjct: 902  VIDEKTQKLYQQEQEILILNE-----KLRETENYIRGIEFQLNELRLKYESQVQITYQKS 956

Query: 1176 IQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEI 1235
              + T + ++T      Q +  QL+ K  QL  +   LL+  ++L     + +     EI
Sbjct: 957  SIIST-SEDITDE---FQSKFQQLQQKYIQLQRDYQILLTNSSKL-EEYENKIALLSLEI 1011

Query: 1236 AEL---WKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQE 1281
            +      K+   Q   +   +    +  L   +S Y + L + QS+T +
Sbjct: 1012 SRYRNSSKKSTPQINRESSSSAKTSKFNLGELQSPYPEELKTEQSNTSQ 1060



 Score = 54.4 bits (125), Expect = 2e-05
 Identities = 131/670 (19%), Positives = 278/670 (41%), Gaps = 68/670 (10%)

Query: 160  VLQVKMKIME--TTILDLQEKI-NEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQ 216
            + Q K++I      I +L+  I N+K Q I  K +                    +   Q
Sbjct: 443  IQQFKLEIQNHLLQISELESSILNQKQQFINQKLELQQHYQQIIEKLQEENKSLQDQNDQ 502

Query: 217  QMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQ 276
            Q+  ++E    +  +   E Q L + I+ KD  +  L     L    + EI   ++K  +
Sbjct: 503  QIQSLEEQGNQI-LQLSSENQELQQIIDEKDQELDKLN----LYVRKQQEIYESNTKKNE 557

Query: 277  ELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNC 336
             LE+                K         K E+ EK  L+   ++        LE+   
Sbjct: 558  ALEESNRELLFKQNSFQKTIKDLYTQLDALKLEVNEKDQLKQQRLS--------LEYEIS 609

Query: 337  QIRQTNKELENKLATMGTE---------SKAVSSPSKKGSPLISRKSGRNTASKMKSPWS 387
            ++ QTN +L  ++  M  E         +  +   + +     S +   ++ +++K  ++
Sbjct: 610  KLNQTNADLLQQITNMKIEINNYQIQITNLNLQIDNTEIELRSSYQENNSSENQLKELFT 669

Query: 388  QL-SSETLNQDTDKKINKNEIAKLEMVIQSLNK-DLVDKEYV--ISEKDTXXXXXXXXXX 443
            ++   ET+    +K+IN++E  +++ ++  L K +  +KEY     E++           
Sbjct: 670  KIEQQETIINQNEKQINEDEF-RIQQLLDELQKLNAKNKEYYKKFEEQEIFIKQLQAELS 728

Query: 444  GKDTLIAQLQ----LEHQQHME--------GPSLIHVGTNTEDVNEIAKVQE--QLKQEL 489
                 I +L+    L+ ++  E           L  V  N  +++  A+ +E  QL   L
Sbjct: 729  ESSNDIKKLENELLLKEEEFNELDDDYNKIWNELNAVKNNQSNLDSNARSEELQQLVANL 788

Query: 490  NDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSK 549
              E  D+ +KDL    K   ++ +QLN +    +K  +KV  N   +L+ +++ I+N   
Sbjct: 789  KSEY-DLVLKDLEALKKQLIDKDSQLNQKAMLVDKFNVKV-MNQTSELRSLKQEIENNQI 846

Query: 550  VSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLA 609
            V ++ ++  R+ ++  H+   +  LE EK + Q  + D             +++E++ L 
Sbjct: 847  VIENQQQ--RIAKQEQHIQDLLRSLESEKKSQQSQVKDNTDN--------SRVMELQQLN 896

Query: 610  ETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKS-VHLEEQI 668
                K I     + +   QE+ IL +K  E E+ +  I + Q +++  + +S V +  Q 
Sbjct: 897  MNLSKVIDEKTQKLYQQEQEILILNEKLRETENYIRGI-EFQLNELRLKYESQVQITYQK 955

Query: 669  DALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIM---NKLQNYIQENMDLTDKLE 725
             ++ ++ ++   + +  +   +QL      L+ D + ++   +KL+ Y  +   L+ ++ 
Sbjct: 956  SSIISTSED---ITDEFQSKFQQLQQKYIQLQRDYQILLTNSSKLEEYENKIALLSLEIS 1012

Query: 726  KMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESI 785
            +       +   +IN E  S  +T      ++Q    Y E +++E S   S+I     S 
Sbjct: 1013 RY-RNSSKKSTPQINRESSSSAKTSKFNLGELQSP--YPEELKTEQSN-TSQIFIQPFSN 1068

Query: 786  AVMEDRRYSL 795
              +++++Y L
Sbjct: 1069 PKVDEQQYGL 1078



 Score = 50.4 bits (115), Expect = 4e-04
 Identities = 39/195 (20%), Positives = 92/195 (47%), Gaps = 6/195 (3%)

Query: 1395 VNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYE 1454
            ++D  +K  + T Q  + + E+  +  +Y   + + N + +  +Q ++  +  I +L   
Sbjct: 124  LHDVISKAEQFTLQCNI-NQELRDQLEQYPEIVIKLNQDLDKYKQDIINNKSSIANL--- 179

Query: 1455 KESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEE 1514
             E  +A L  ++H      E  Q ++ + + ++  +L  ++ E      Q  + N+ LE+
Sbjct: 180  -EQTIADLNQEIHILKQLLEQEQNKNSLNQSQIQLQLETQLNELRLKLSQTEQKNEELED 238

Query: 1515 EVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDN 1574
            EV + N  +  +E+Q  EI+  N++I   ++ + + +  +  H    SD    +  Q + 
Sbjct: 239  EVEQINFFKVQMESQLQEILKENNKIMVDKDKLASDNLSLNTHNDDLSDQLNLQTSQ-NQ 297

Query: 1575 TMNKELLDAVPRAEL 1589
             +NK++L+   +  L
Sbjct: 298  DLNKKILELEDQVRL 312


>UniRef50_Q6C359 Cluster: Similar to DEHA0C09658g Debaryomyces
            hansenii IPF 1836.1; n=1; Yarrowia lipolytica|Rep:
            Similar to DEHA0C09658g Debaryomyces hansenii IPF 1836.1
            - Yarrowia lipolytica (Candida lipolytica)
          Length = 1906

 Score =  153 bits (370), Expect = 5e-35
 Identities = 234/1259 (18%), Positives = 491/1259 (38%), Gaps = 89/1259 (7%)

Query: 359  VSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLN 418
            +  PS      IS +  ++    +KS   +L   +      K     EI  L+ +   L 
Sbjct: 699  LKDPSHSAGGKISYELVQSLEDNVKSLTDELEEVSTALSETKSATSAEIKDLKAIRDDLE 758

Query: 419  KDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEI 478
            +DL + +  + E              K  + A+ QL+     E  S   + T   D+ + 
Sbjct: 759  RDLQETDTRLKEARGALESLEGKFHTK--VAAEKQLQTSLEAERKSGSGLQTELADLKKK 816

Query: 479  AKVQEQLKQELNDEIKDVNV-KDLIEK-LKSAEEQITQLNDEIDAANKNMIKVKSNHKLK 536
             +   Q K +L  +++ +   KD  E  +    +++ QL  E D ++K            
Sbjct: 817  LQTLTQQKTQLTTQVETLTAAKDKAESGINKMSKELFQLTRERDGSDKEK---------- 866

Query: 537  LKQMQKTIDNFSKVSDSNK-EIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIE 595
             K +QK +    K   S + E+  L   L  ++   ++ E     LQ    ++     ++
Sbjct: 867  -KGLQKELAELKKQDSSRRTELTALAANLKQVTAARSDFENRLKGLQS---EHSETETLK 922

Query: 596  SDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQV 655
              + +K+       E      + LE Q  +L      LQ  YDE++     +S +  D  
Sbjct: 923  DKLIEKLKSAATQLEDHKSRGANLEGQIRELQGSHEALQNSYDELQKSHEQLSSVGKDNE 982

Query: 656  CSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQ 715
                +   L+ ++  +       A  +  L+          K +  +KE +  ++  + +
Sbjct: 983  SLASELAELKTKLSKIETESSSRADKVSELEKSLSAAEAQSKSVAAEKEKVSGQIATHEE 1042

Query: 716  ENMDLTDKLEKMSAE--KISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSK 773
                L ++L + +AE  K+   LA    +  SK +     D +I++    +E   S+L+ 
Sbjct: 1043 TIKRLKEELSERTAELDKLKSDLASSEKDLASKTKDVSAKDTEIEKLKSELETANSKLAS 1102

Query: 774  YKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAY----SEYTIQEDELVNRLAV 829
                +  L   +   +      E K   + S L E++       +E   +   + +  A 
Sbjct: 1103 TAKEVEILTSELKAAKSDACDSETKIKAVESELVEQKSKVEHLNAELAAKSSSVESGAAE 1162

Query: 830  LMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLA 889
            L +   +VE    ++E ++KEL  K + L  + + L+   S+++     L  K+      
Sbjct: 1163 LAEKVALVESLTAKLESKDKELATKTEELSAKEKELETKTSELETKTAELTTKSKELTAK 1222

Query: 890  ESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEK 949
              E+T Y  ++++LE++   +  +  TL        +DL  E   ++ +A  + +  N  
Sbjct: 1223 SDEATTYSAKVKELETSSAALEKKQTTLKAMADNLTKDL-AEKTKELVAAKSELESSNTS 1281

Query: 950  YEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYIN 1009
             ++ ++ +T+  +        ++  +   E      +  ++  + K    S         
Sbjct: 1282 SKEEVDVLTKKLSDATAEAVELKKSSQAAETEASSKVSALEAKLTKASESSK-------A 1334

Query: 1010 EINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSK 1069
            E++K+N LL        +  +K+  ++  + + VS    ++ + T K EN E ++  +  
Sbjct: 1335 ELDKVNKLLS-------SFKEKLQTSKDDHSTEVSKLTEQVRESTLKAENFEHDISSLKD 1387

Query: 1070 QLLDSKQHNEELQILVREQDDQIKEL--KETKLTFEMNIPKTEGMIISSTIEPMSDDANN 1127
             L  +++  + L+    E D  IKE+  + T LT + +    E     S ++   D+   
Sbjct: 1388 DLAQAEKERDALR---TELDTSIKEMENERTSLTKDADSATKELTNKVSMLQTKLDELTA 1444

Query: 1128 VDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTG 1187
                             +E +    E   L+E  AK     +   T I  LE   +ELT 
Sbjct: 1445 SHKKALGDSETEAKGLKKEIKAAQAEIKTLEEVKAK----YEASQTDIKGLEKQVSELT- 1499

Query: 1188 HDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQRE 1247
                  E +    S+ E + T  +  L   +  +S + + V +   E+A+   +H  +  
Sbjct: 1500 ------ESLETKTSETEAVKTALEEKLEEASSAKSKLETKVTELEKEVADNQGKH-GKAA 1552

Query: 1248 ADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQE-ETNKIVTMEQVTSLQNKLQDKEEHL 1306
            ++ + +   L+ ++S  ++  ++L  S +++  +  + +   M +VT L+ +L D ++ L
Sbjct: 1553 SELEASVKTLKSEISTHKATIDELKKSAETAAADTSSERTELMSKVTELETQLADAKKEL 1612

Query: 1307 RNLQEKYAD--------------VINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDL 1352
             N++  +AD               + ++    +++E E                    DL
Sbjct: 1613 DNVKSTHADGSKKQASELNELKTKLEEVATANTKLETELKNASAKLEEEQAAKTKLSSDL 1672

Query: 1353 RTENQ---SYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQL 1409
              + +    ++   + S    +EE A LK                  + + K+ +L  +L
Sbjct: 1673 EAKTKVSADFETELKASQTQHDEEVASLKMEIKSLRDEQTSNASSAGEFKGKIEKLEVEL 1732

Query: 1410 ELKDSEIYQKT---HEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKES---ELAILR 1463
            + K++E+  K       +  L   + E ++   +L      ++  T E ES   EL  + 
Sbjct: 1733 KTKETELQTKASNLESASSALEAASKELKSKATELESASSELKSKTSELESKTTELKTIN 1792

Query: 1464 LKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQ 1523
             ++ +  +  +T  K +E+E  K  E   V  T+S +  K +AEL ++  +E+ KTN+ +
Sbjct: 1793 TELKDRTSELKT--KTTELES-KSTELKTVSDTQSAT-EKALAEL-QSKYDELLKTNKAK 1847

Query: 1524 TALENQEI---EIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKE 1579
            +A     +   E   L   IT+L   V     K+++H    SD     D+  D+  + E
Sbjct: 1848 SAATKDMVPKSEYEELMLMITDLDEKVEKYKEKLEEHGVEISDDDDDDDDDDDDDEDDE 1906



 Score =  118 bits (283), Expect = 2e-24
 Identities = 217/1079 (20%), Positives = 457/1079 (42%), Gaps = 97/1079 (8%)

Query: 215  KQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISL--EHS 272
            + ++T +  N   + A   D + RL K ++S+     +L++  KL+E  +   +   +H 
Sbjct: 884  RTELTALAANLKQVTAARSDFENRL-KGLQSEHSETETLKD--KLIEKLKSAATQLEDHK 940

Query: 273  KLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLE 332
                 LE                +   ++ S E+ + + +      + + EL  K+  +E
Sbjct: 941  SRGANLEGQIRELQGSHEALQN-SYDELQKSHEQLSSVGKDNESLASELAELKTKLSKIE 999

Query: 333  HLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSE 392
              +        ELE  L+    +SK+V++  +K S  I+  +   T  ++K   S+ ++E
Sbjct: 1000 TESSSRADKVSELEKSLSAAEAQSKSVAAEKEKVSGQIA--THEETIKRLKEELSERTAE 1057

Query: 393  TLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVI----SEKDTXXXXXXXXXXGKDTL 448
                  DK   K+++A  E  + S  KD+  K+  I    SE +T            + L
Sbjct: 1058 -----LDKL--KSDLASSEKDLASKTKDVSAKDTEIEKLKSELETANSKLASTAKEVEIL 1110

Query: 449  IAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSA 508
             ++L+       +  + I     +E V + +KV E L  EL    K  +V+    +L   
Sbjct: 1111 TSELKAAKSDACDSETKIK-AVESELVEQKSKV-EHLNAEL--AAKSSSVESGAAELAEK 1166

Query: 509  EEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQ-KTIDNFSKVSD---SNKEIVRLTEEL 564
               +  L  ++++ +K +         K K+++ KT +  +K ++    +KE+   ++E 
Sbjct: 1167 VALVESLTAKLESKDKELATKTEELSAKEKELETKTSELETKTAELTTKSKELTAKSDEA 1226

Query: 565  HHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKF 624
               S KV ELE     L+         + +  ++ K + E     +  + A S LES   
Sbjct: 1227 TTYSAKVKELETSSAALEKKQTTL---KAMADNLTKDLAEK---TKELVAAKSELESSNT 1280

Query: 625  DLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIEN 684
               +E+ +L +K   + D  A+  +L+     +E ++     ++ AL A K   A     
Sbjct: 1281 SSKEEVDVLTKK---LSDATAEAVELKKSSQAAETEA---SSKVSALEA-KLTKASESSK 1333

Query: 685  LKLDK-EQLYGTIKD-LENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHE 742
             +LDK  +L  + K+ L+  K+D   ++    ++  + T K E    + IS L   +   
Sbjct: 1334 AELDKVNKLLSSFKEKLQTSKDDHSTEVSKLTEQVRESTLKAENFEHD-ISSLKDDLAQA 1392

Query: 743  EQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQL 802
            E+ +   +  +D  I+E    +EN  + L+K        + +   + ++   L+ K D+L
Sbjct: 1393 EKERDALRTELDTSIKE----MENERTSLTK------DADSATKELTNKVSMLQTKLDEL 1442

Query: 803  GSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEEN 862
             +     +KA  +   +   L   +       + +E+   + E    +++   + + E  
Sbjct: 1443 TA---SHKKALGDSETEAKGLKKEIKAAQAEIKTLEEVKAKYEASQTDIKGLEKQVSELT 1499

Query: 863  QNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKK 922
            ++L+   S+ +    AL EK      A S  +K +T++ +LE  +     +H        
Sbjct: 1500 ESLETKTSETEAVKTALEEKLEE---ASSAKSKLETKVTELEKEVADNQGKH-------G 1549

Query: 923  KEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELN 982
            K   +LE    T ++S I   K   ++ +K+       E    +  +    L   V EL 
Sbjct: 1550 KAASELEASVKT-LKSEISTHKATIDELKKS------AETAAADTSSERTELMSKVTEL- 1601

Query: 983  KMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSM 1042
            +  L    K +   ++   D +++  +E+N+    LK K EE+   N K+     +  + 
Sbjct: 1602 ETQLADAKKELDNVKSTHADGSKKQASELNE----LKTKLEEVATANTKLETELKNASAK 1657

Query: 1043 VSDYESKLAQFTTKLENMEEEMQRVSKQLLDSK-QHNEELQILVREQDDQIKELKETKLT 1101
            + + ++   + ++ LE   +       +L  S+ QH+EE+  L  E    IK L++ + +
Sbjct: 1658 LEEEQAAKTKLSSDLEAKTKVSADFETELKASQTQHDEEVASLKME----IKSLRDEQTS 1713

Query: 1102 FEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQS 1161
               +  + +G I    +E +      +             L+    +E   + + L+  S
Sbjct: 1714 NASSAGEFKGKIEKLEVE-LKTKETELQTKASNLESASSALEA-ASKELKSKATELESAS 1771

Query: 1162 AKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELR 1221
            ++L ++  E  +K  +L+T+NTEL       +++ ++LK+K  +L +++   L TV++ +
Sbjct: 1772 SELKSKTSELESKTTELKTINTEL-------KDRTSELKTKTTELESKSTE-LKTVSDTQ 1823

Query: 1222 SSISSAVDQRGFEIAELWKQHLAQREAD---FQKTEH-ELRVQLSAFESKYEQLLDSVQ 1276
            S+   A+ +   +  EL K + A+  A      K+E+ EL + ++  + K E+  + ++
Sbjct: 1824 SATEKALAELQSKYDELLKTNKAKSAATKDMVPKSEYEELMLMITDLDEKVEKYKEKLE 1882



 Score = 50.8 bits (116), Expect = 3e-04
 Identities = 76/426 (17%), Positives = 168/426 (39%), Gaps = 17/426 (3%)

Query: 1168 LQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSA 1227
            ++E +T++ +    +   +    ++ E +  L+  ++ L  E + + + ++E +S+ S+ 
Sbjct: 687  VKENFTRLSRALLKDPSHSAGGKISYELVQSLEDNVKSLTDELEEVSTALSETKSATSA- 745

Query: 1228 VDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIV 1287
                  EI +L K      E D Q+T+  L+    A ES   +    V +  Q +T+   
Sbjct: 746  ------EIKDL-KAIRDDLERDLQETDTRLKEARGALESLEGKFHTKVAAEKQLQTSLEA 798

Query: 1288 TMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXX 1347
              +  + LQ +L D ++ L+ L ++   +  Q+E L +  +  +                
Sbjct: 799  ERKSGSGLQTELADLKKKLQTLTQQKTQLTTQVETLTAAKDKAESGINKMSKELFQLTRE 858

Query: 1348 XXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTH 1407
                 + +    K++ E   L   + + + + ++               +   K L+  H
Sbjct: 859  RDGSDKEKKGLQKELAE---LKKQDSSRRTELTALAANLKQVTAARSDFENRLKGLQSEH 915

Query: 1408 -QLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKM 1466
             + E    ++ +K       L        N+  Q+ E +   E L    + EL     K 
Sbjct: 916  SETETLKDKLIEKLKSAATQLEDHKSRGANLEGQIRELQGSHEALQNSYD-ELQ----KS 970

Query: 1467 HENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTAL 1526
            HE  +      +    E  +L  +L+   TES S   +V+EL K+L    A++  +    
Sbjct: 971  HEQLSSVGKDNESLASELAELKTKLSKIETESSSRADKVSELEKSLSAAEAQSKSVAAEK 1030

Query: 1527 ENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPR 1586
            E    +I T  + I  L+  +   ++++ K  S  + +++    +  +   K+      +
Sbjct: 1031 EKVSGQIATHEETIKRLKEELSERTAELDKLKSDLASSEKDLASKTKDVSAKDTEIEKLK 1090

Query: 1587 AELDLA 1592
            +EL+ A
Sbjct: 1091 SELETA 1096


>UniRef50_UPI0000F2140F Cluster: PREDICTED: similar to nuclear mitotic
            apparatus protein 1,, partial; n=2; Danio rerio|Rep:
            PREDICTED: similar to nuclear mitotic apparatus protein
            1,, partial - Danio rerio
          Length = 1886

 Score =  152 bits (369), Expect = 7e-35
 Identities = 294/1422 (20%), Positives = 585/1422 (41%), Gaps = 147/1422 (10%)

Query: 233  KDEKQR-LLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXX 291
            KDE+ R L K+ ES D  +  ++E N  + A       EH +  ++L+Q           
Sbjct: 320  KDEEIRNLTKEYESVDNELKLVKEQNVEINAMIKSNRKEHEETVEKLQQELHCAASAASE 379

Query: 292  XXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLAT 351
                 +Q +  S  E T ++E+      N  +  +++ +LE  +  +++    L+N+LA 
Sbjct: 380  K---QEQMLVLSA-EVTSLKEQICRYSENEAQKQQELSILEAQHNVLKENLTSLQNQLA- 434

Query: 352  MGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLS-SETLNQDTDKKINKNEIAKL 410
                 +A +S S+K S  I  +              +LS  ETL + T +++ K +  +L
Sbjct: 435  -----EATTSASQKESEFILLQ-------------QELSHQETLREQT-QELEKIKREEL 475

Query: 411  EMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGT 470
            E ++  L   +++   + SE              ++  ++ LQ E +  +          
Sbjct: 476  EGIVSELQAKIIEVSSIASE--------------REACVSSLQYEMKDQLSKAKQCEADL 521

Query: 471  NTEDVNEIAKVQEQLKQELNDEI--KDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIK 528
              E   ++  +QE L    N  I  K+ +++ L + LK  E    Q  +EI A+ +   +
Sbjct: 522  RNEMKEKVGNLQE-LLDAANHGIAEKEHHLESLNQSLKQMELLYCQKEEEIIASQQAKEQ 580

Query: 529  VKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDY 588
            +++N    + + ++ +D   +    N+EI+R   E  HLS +V+ L+EE    Q    D 
Sbjct: 581  LENN----IAEQKQQLDEIQQ----NREILR--NERDHLSTRVSSLQEEIHCSQQEFSDL 630

Query: 589  DSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADIS 648
             +   +   + +K++ ++N  E  +   S  ES+   L QEL   Q+   E   +L  I 
Sbjct: 631  QTDHNV---LKEKLVNLQNQLEQAMITASQKESELLLLQQELS-HQETLREKALELEAIK 686

Query: 649  QLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMN 708
            + + ++   E++   LE  +  L++ ++   + +EN   D++      KD  N   +   
Sbjct: 687  REEFEKKVKELQDRILE--VSTLASQREAQVISLENEMRDQQLSANQSKD--NLCREWQE 742

Query: 709  KLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGI-DAKIQERDLYIENI 767
            KL   ++  +D+  +       ++  L  K+   E   +Q +  + +    + DL     
Sbjct: 743  KL-GILKGELDVVSRDAADKDHQLESLDQKLKEMEMVVLQKEKDVMETHQAKEDLEKRIA 801

Query: 768  ESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRL 827
            E E  K K  I R E      E    SL+ +         +KQ+  S   ++ + L   +
Sbjct: 802  ELEECKQKLEIMRNERDHLSTEVA--SLKEEIHSYQDTQMQKQQTISVLEVENNALKENM 859

Query: 828  AVLMDHDRVVEKQLLEIEHENKELQKK---NQILLEENQNLQISL-SDMQQHYNALVEKA 883
            A L   ++ + +++     +N ELQ K    + L E+ Q L+I    + ++    L  K 
Sbjct: 860  AAL---EKQLAEEITTASQKNSELQNKLHQQESLHEKAQELEIGRHEEFERRVRELQAKV 916

Query: 884  NR--TDLAESESTKYQTQLRDLESNLK-RITHEHQTLIVQKKKEIEDLEIEFNTQIESAI 940
                T  +E E+  Y  Q  +L  +LK +++ +    ++++K E    EIE     ++  
Sbjct: 917  QEVSTLASEKEAVAYSLQ-EELTGHLKAKVSEDDLRRVLEEKVETLQREIE-TASCDATS 974

Query: 941  RD--KKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELID--KH---V 993
            +D   + L++K  +      Q E  + E +N+ E+L   + EL   N EL    +H   V
Sbjct: 975  KDGLLQTLDQKLRQMEMLCQQKEDAVFEIQNSKEDLQKEMNELVSKNQELEGCLQHLEMV 1034

Query: 994  QKQQTQSPDYTEQYINEINKLNALLKQKDEEII-ALNQKINNAQVSYMSM---VSDYESK 1049
            +K++    +       +IN  +   KQ + ++     +KI   Q    S    VS+ E  
Sbjct: 1035 KKEKDLLSNEVTSLKEQINDQSLRAKQSEADLCKVFEEKIETLQGQLESSSRDVSEKEKH 1094

Query: 1050 LAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKT 1109
            L     K+  M+   Q+    +L+ +   E+LQ  + E   + ++L+      EM   K+
Sbjct: 1095 LQTLHQKVSQMDLLCQQKENAVLEMQNAKEDLQKKIDELVSEKQQLEGCLQNLEM--VKS 1152

Query: 1110 EGMIISSTIEPMSDDANNVDXXXXXXXXXXXXL----------KVQEEEEFIQERSVLQE 1159
            E  ++S+ +  + D  N+ D            +          +++     + E+  L +
Sbjct: 1153 ERDLLSTEVTSIKDQLNDQDLKAKQSEDDLRKVLEEKIKNLQGQLETASRDVSEKDQLLQ 1212

Query: 1160 QSAKLNTELQECYTK-------IIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDN 1212
               +  T++ + Y K       ++Q++    +  G  +V ++Q+   +  LE ++   DN
Sbjct: 1213 TLDQKVTQMDQLYKKKEKYALDLLQVKENLEKRIGEIIVEKQQLEGCQQNLETVSKAKDN 1272

Query: 1213 LLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHE-LRVQLSAFESKYEQL 1271
            LL+ +  L+  I S      ++  E+  +H    E    + EH  L+  L   + +  +L
Sbjct: 1273 LLNELTSLKVEIQS------YQEKEVQMKH----ELSVLENEHNILQENLDTLQKQVVEL 1322

Query: 1272 LDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVIN-------QIEILR 1324
              S      E  N++   E+   LQ K Q  E+   +LQ K  ++         QI  L+
Sbjct: 1323 TVSASQKESELQNEVCKQEK---LQEKAQKLEKDAGDLQAKILEISTLASEREAQISSLK 1379

Query: 1325 SEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYK---QMQEQSILNINEENAQLKKSS 1381
             EI  + +                  +L+ + +  +     ++Q +  +N++  Q+++  
Sbjct: 1380 DEINSQHLKAKQSEDDLLRVFEEKIENLQGQLEIARLDVSDKDQLLQTLNQKLKQMEELC 1439

Query: 1382 XXXXXXXXXXXXRVNDAEAKVLEL---THQLELKDSEIYQKTHEYTITLTQR-NDEFENV 1437
                           D E K++EL     Q   ++ E+ ++  ++  +L Q    E E  
Sbjct: 1440 KQKETCVLEMHQTKEDLEKKIVELQADKSQQNQQNLEMLRQEKDHLKSLNQTIRRECEAS 1499

Query: 1438 RQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQ----KESEIERVKL-IEELN 1492
            R+   E E  +E+ T    S LA+ +        + E ++    K   +E  K  +E+  
Sbjct: 1500 RKIRAELELNVEEQT---ASILALKKASQQWEEQNQELLEQLKAKTEAVEHYKAQVEKAM 1556

Query: 1493 VKITESVSLNKQVAELNKALEE--EVAK--TNEMQTALENQEIEIVTLNDEITNLQNMVR 1548
                    L  +  ELNK LE+  EV+K     ++T L    +E+   ND+  +L   V+
Sbjct: 1557 NHYNGKKQLLLEAQELNKTLEQSLEVSKREAKALETELTLARMELNQANDKEKSLAAKVK 1616

Query: 1549 ASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELD 1590
               +++        + ++  D+  D    + L   VP  + D
Sbjct: 1617 TLEAQVDFADRQLREKRRIADDGEDLRQKENLYFRVPEKQQD 1658



 Score =  144 bits (350), Expect = 1e-32
 Identities = 280/1465 (19%), Positives = 619/1465 (42%), Gaps = 146/1465 (9%)

Query: 215  KQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKL 274
            +Q++ K+     + + EWK+ K+ L K++         L E   +L+    +IS+    L
Sbjct: 15   EQEVAKLTVVHESAQTEWKNRKELLEKELNEAVTHKECLSEQVLILQG---KISV----L 67

Query: 275  AQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEH- 333
              EL++                ++SI    ++K E+E   + E  +  + T +++L+   
Sbjct: 68   EDELKKAQSQERGEVLGPIMELQESISHLEKKKAEVEALLAEERCSFEKETARLQLVVFD 127

Query: 334  LNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSET 393
            L   I     E E     + T+ + +S+        + R   R    +++       S  
Sbjct: 128  LEKSINSIRLERETLQEALKTQKEMLSAQISA----LERDVSRLQQVEVQLTAEIKISAD 183

Query: 394  LNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYV-ISEKDTXXXXXXXXXXGKDTLIA-Q 451
            L Q  ++   K  +A L+ ++ SL+ ++   E    S++D            + T+   +
Sbjct: 184  LRQQREELEGK--VASLDRMVHSLHAEIQGLEVERASQQDAINSLISDLQIARATVQEYE 241

Query: 452  LQLEHQQHM--EGPSLIHVG-TNTEDVNEIAKVQEQLKQELND----EIKDVN-VKDLIE 503
             +LE  Q +  E  SL +   T  +++N   K    L+ E+N+    + ++ N V + + 
Sbjct: 242  KKLEEHQKVVAENNSLKNEACTMQQELNNHLKAIGDLQAEVNELRFEKTEEENKVSEALV 301

Query: 504  KLKSAEEQITQLNDEI---DAANKNMIKVKSNHKLKLKQM-QKTIDNFSKVSDSNKE--- 556
            K++S + +I  L ++I   D   +N+ K   +   +LK + ++ ++  + +  + KE   
Sbjct: 302  KIESLQTEILHLCEKISLKDEEIRNLTKEYESVDNELKLVKEQNVEINAMIKSNRKEHEE 361

Query: 557  -IVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKA 615
             + +L +ELH  +   +E +E+   L   +        ++  + +     EN A+ + + 
Sbjct: 362  TVEKLQQELHCAASAASEKQEQMLVLSAEVTS------LKEQICRYS---ENEAQKQ-QE 411

Query: 616  ISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVH---LEEQIDALS 672
            +S+LE+Q   L + L  LQ   +++ +     SQ +S+ +  + +  H   L EQ   L 
Sbjct: 412  LSILEAQHNVLKENLTSLQ---NQLAEATTSASQKESEFILLQQELSHQETLREQTQELE 468

Query: 673  ASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKI 732
              K+E    +E +  + +     +  + +++E  ++ LQ    E  D   K ++  A+  
Sbjct: 469  KIKRE---ELEGIVSELQAKIIEVSSIASEREACVSSLQ---YEMKDQLSKAKQCEADLR 522

Query: 733  SELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRR 792
            +E+  K+ + ++       GI     E++ ++E++   L + +   C+ EE I   +  +
Sbjct: 523  NEMKEKVGNLQELLDAANHGI----AEKEHHLESLNQSLKQMELLYCQKEEEIIASQQAK 578

Query: 793  YSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQ 852
              LE    +    L E Q+       + D L  R++ L +     +++  +++ ++  L+
Sbjct: 579  EQLENNIAEQKQQLDEIQQNREILRNERDHLSTRVSSLQEEIHCSQQEFSDLQTDHNVLK 638

Query: 853  KKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRD-LESNLKRIT 911
            +K   L  + +   I+ S  +     L ++ +  +    ++ + +   R+  E  +K + 
Sbjct: 639  EKLVNLQNQLEQAMITASQKESELLLLQQELSHQETLREKALELEAIKREEFEKKVKELQ 698

Query: 912  H---EHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVT-QLEAQLQEY 967
                E  TL  Q++ ++  LE E   Q  SA + K  L  ++++ +  +  +L+   ++ 
Sbjct: 699  DRILEVSTLASQREAQVISLENEMRDQQLSANQSKDNLCREWQEKLGILKGELDVVSRDA 758

Query: 968  KNNIENLNMNVEELNKMNLELIDKHVQKQQT-QSPDYTEQYINEIN----KLNALLKQKD 1022
             +    L    ++L +M + ++ K     +T Q+ +  E+ I E+     KL  +  ++D
Sbjct: 759  ADKDHQLESLDQKLKEMEMVVLQKEKDVMETHQAKEDLEKRIAELEECKQKLEIMRNERD 818

Query: 1023 E---EIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNE 1079
                E+ +L ++I++ Q + M           +     ENM    +++++++  + Q N 
Sbjct: 819  HLSTEVASLKEEIHSYQDTQMQKQQTISVLEVENNALKENMAALEKQLAEEITTASQKNS 878

Query: 1080 ELQILVREQDDQIKELKETKL----TFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXX 1135
            ELQ  + +Q+   ++ +E ++     FE  + + +  +    +  ++ +   V       
Sbjct: 879  ELQNKLHQQESLHEKAQELEIGRHEEFERRVRELQAKV--QEVSTLASEKEAVAYSLQEE 936

Query: 1136 XXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQ----ECYTKIIQLETLNTELTGHDVV 1191
                   KV E++     R VL+E+   L  E++    +  +K   L+TL+ +L   +++
Sbjct: 937  LTGHLKAKVSEDDL----RRVLEEKVETLQREIETASCDATSKDGLLQTLDQKLRQMEML 992

Query: 1192 NQEQ---INQLKSKLEQLNTENDNLLSTVAELRSS------ISSAVDQRGFEIAELWKQH 1242
             Q++   + ++++  E L  E + L+S   EL         +    D    E+  L K+ 
Sbjct: 993  CQQKEDAVFEIQNSKEDLQKEMNELVSKNQELEGCLQHLEMVKKEKDLLSNEVTSL-KEQ 1051

Query: 1243 LAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNK---IVTMEQVTSLQNKL 1299
            +  +    +++E +L      FE K E L   ++SS+++ + K   + T+ Q  S  + L
Sbjct: 1052 INDQSLRAKQSEADL---CKVFEEKIETLQGQLESSSRDVSEKEKHLQTLHQKVSQMDLL 1108

Query: 1300 -QDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQS 1358
             Q KE  +  +Q    D+  +I+ L SE +  +                    L TE  S
Sbjct: 1109 CQQKENAVLEMQNAKEDLQKKIDELVSEKQQLEGCLQNLEMVKSERDL-----LSTEVTS 1163

Query: 1359 YKQMQEQSILNINEENAQLKK---SSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSE 1415
             K       L   +    L+K                 R    + ++L+   Q   +  +
Sbjct: 1164 IKDQLNDQDLKAKQSEDDLRKVLEEKIKNLQGQLETASRDVSEKDQLLQTLDQKVTQMDQ 1223

Query: 1416 IYQKTHEYTITLTQRNDEFEN-------VRQQLVEYEKRIEDLTYEKES---ELAILRLK 1465
            +Y+K  +Y + L Q  +  E         +QQL   ++ +E ++  K++   EL  L+++
Sbjct: 1224 LYKKKEKYALDLLQVKENLEKRIGEIIVEKQQLEGCQQNLETVSKAKDNLLNELTSLKVE 1283

Query: 1466 M-----------HENA---NHYETMQKESEIERVKLIE----------ELNVKITESVSL 1501
            +           HE +   N +  +Q+  +  + +++E          EL  ++ +   L
Sbjct: 1284 IQSYQEKEVQMKHELSVLENEHNILQENLDTLQKQVVELTVSASQKESELQNEVCKQEKL 1343

Query: 1502 NKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFA 1561
             ++  +L K   +  AK  E+ T    +E +I +L DEI +     + S   + +     
Sbjct: 1344 QEKAQKLEKDAGDLQAKILEISTLASEREAQISSLKDEINSQHLKAKQSEDDLLRVFEEK 1403

Query: 1562 SDTKQGRDE--QLDNTMNKELLDAV 1584
             +  QG+ E  +LD +   +LL  +
Sbjct: 1404 IENLQGQLEIARLDVSDKDQLLQTL 1428



 Score =  134 bits (325), Expect = 1e-29
 Identities = 267/1430 (18%), Positives = 603/1430 (42%), Gaps = 134/1430 (9%)

Query: 212  EDTKQQMTKMQENFIAMEAEWK----DEKQRLLKDIESKDVRISSLEEANKLLEAARFEI 267
            E   +Q+  +Q     +E E K     E+  +L  I      IS LE+    +EA   E 
Sbjct: 51   ECLSEQVLILQGKISVLEDELKKAQSQERGEVLGPIMELQESISHLEKKKAEVEALLAEE 110

Query: 268  SLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEI--EEKGSLE--IANMTE 323
                 K    L Q              L +++++ + + + E+   +  +LE  ++ + +
Sbjct: 111  RCSFEKETARL-QLVVFDLEKSINSIRLERETLQEALKTQKEMLSAQISALERDVSRLQQ 169

Query: 324  LTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPL-ISRKSGRNTASKM 382
            +  ++     ++  +RQ  +ELE K+A++    + V S   +   L + R S ++  + +
Sbjct: 170  VEVQLTAEIKISADLRQQREELEGKVASL---DRMVHSLHAEIQGLEVERASQQDAINSL 226

Query: 383  KSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXX 442
             S   Q++  T+ Q+ +KK+ +++    E      N  L ++   + ++           
Sbjct: 227  ISD-LQIARATV-QEYEKKLEEHQKVVAE------NNSLKNEACTMQQELNNHLKA---- 274

Query: 443  XGKDTLIAQLQLEHQQHMEGPSLIHVGTNTED-VNEIAKVQEQLKQELNDEIKDVNVKDL 501
                  I  LQ E  +      L    T  E+ V+E     E L+ E+    + +++KD 
Sbjct: 275  ------IGDLQAEVNE------LRFEKTEEENKVSEALVKIESLQTEILHLCEKISLKD- 321

Query: 502  IEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLT 561
             E++++  ++   +++E+    +  +++ +  K   K+ ++T++             +L 
Sbjct: 322  -EEIRNLTKEYESVDNELKLVKEQNVEINAMIKSNRKEHEETVE-------------KLQ 367

Query: 562  EELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLES 621
            +ELH  +   +E +E+   L   +        ++  + +     EN A+ + + +S+LE+
Sbjct: 368  QELHCAASAASEKQEQMLVLSAEVTS------LKEQICR---YSENEAQ-KQQELSILEA 417

Query: 622  QKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVH---LEEQIDALSASKKEL 678
            Q   L + L  LQ   +++ +     SQ +S+ +  + +  H   L EQ   L   K+E 
Sbjct: 418  QHNVLKENLTSLQ---NQLAEATTSASQKESEFILLQQELSHQETLREQTQELEKIKRE- 473

Query: 679  ALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAK 738
               +E +  + +     +  + +++E  ++ LQ    E  D   K ++  A+  +E+  K
Sbjct: 474  --ELEGIVSELQAKIIEVSSIASEREACVSSLQ---YEMKDQLSKAKQCEADLRNEMKEK 528

Query: 739  INHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERK 798
            + + ++       G    I E++ ++E++   L + +   C+ EE I   +  +  LE  
Sbjct: 529  VGNLQELLDAANHG----IAEKEHHLESLNQSLKQMELLYCQKEEEIIASQQAKEQLENN 584

Query: 799  ADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQIL 858
              +    L E Q+       + D L  R++ L +     +++  +++ ++  L++K   L
Sbjct: 585  IAEQKQQLDEIQQNREILRNERDHLSTRVSSLQEEIHCSQQEFSDLQTDHNVLKEKLVNL 644

Query: 859  LEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLR-DLESNLKRITH---EH 914
              + +   I+ S  +     L ++ +  +    ++ + +   R + E  +K +     E 
Sbjct: 645  QNQLEQAMITASQKESELLLLQQELSHQETLREKALELEAIKREEFEKKVKELQDRILEV 704

Query: 915  QTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVT-QLEAQLQEYKNNIEN 973
             TL  Q++ ++  LE E   Q  SA + K  L  ++++ +  +  +L+   ++  +    
Sbjct: 705  STLASQREAQVISLENEMRDQQLSANQSKDNLCREWQEKLGILKGELDVVSRDAADKDHQ 764

Query: 974  LNMNVEELNKMNLELIDKHVQKQQT-QSPDYTEQYINEI----NKLNALLKQKDE---EI 1025
            L    ++L +M + ++ K     +T Q+ +  E+ I E+     KL  +  ++D    E+
Sbjct: 765  LESLDQKLKEMEMVVLQKEKDVMETHQAKEDLEKRIAELEECKQKLEIMRNERDHLSTEV 824

Query: 1026 IALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILV 1085
             +L ++I++ Q + M           +     ENM    +++++++  + Q N ELQ  +
Sbjct: 825  ASLKEEIHSYQDTQMQKQQTISVLEVENNALKENMAALEKQLAEEITTASQKNSELQNKL 884

Query: 1086 REQDDQIKELKETKL----TFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXX 1141
             +Q+   ++ +E ++     FE  + + +  +    +  ++ +   V             
Sbjct: 885  HQQESLHEKAQELEIGRHEEFERRVRELQAKV--QEVSTLASEKEAVAYSLQEELTGHLK 942

Query: 1142 LKVQEEEEFIQERSVLQEQSAKLNTELQ----ECYTKIIQLETLNTELTGHDVVNQEQ-- 1195
             KV E++     R VL+E+   L  E++    +  +K   L+TL+ +L   +++ Q++  
Sbjct: 943  AKVSEDD----LRRVLEEKVETLQREIETASCDATSKDGLLQTLDQKLRQMEMLCQQKED 998

Query: 1196 -INQLKSKLEQLNTENDNLLSTVAELR------SSISSAVDQRGFEIAELWKQHLAQREA 1248
             + ++++  E L  E + L+S   EL         +    D    E+  L K+ +  +  
Sbjct: 999  AVFEIQNSKEDLQKEMNELVSKNQELEGCLQHLEMVKKEKDLLSNEVTSL-KEQINDQSL 1057

Query: 1249 DFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNK---IVTMEQVTSLQNKL-QDKEE 1304
              +++E +L      FE K E L   ++SS+++ + K   + T+ Q  S  + L Q KE 
Sbjct: 1058 RAKQSEADL---CKVFEEKIETLQGQLESSSRDVSEKEKHLQTLHQKVSQMDLLCQQKEN 1114

Query: 1305 HLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQE 1364
             +  +Q    D+  +I+ L SE +  +                    L TE  S K    
Sbjct: 1115 AVLEMQNAKEDLQKKIDELVSEKQQLEGCLQNLEMVKSERDL-----LSTEVTSIKDQLN 1169

Query: 1365 QSILNINEENAQLKK---SSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTH 1421
               L   +    L+K                 R    + ++L+   Q   +  ++Y+K  
Sbjct: 1170 DQDLKAKQSEDDLRKVLEEKIKNLQGQLETASRDVSEKDQLLQTLDQKVTQMDQLYKKKE 1229

Query: 1422 EYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESE 1481
            +Y + L Q  +  E    +++  ++++E      E+        ++E  +    +Q   E
Sbjct: 1230 KYALDLLQVKENLEKRIGEIIVEKQQLEGCQQNLETVSKAKDNLLNELTSLKVEIQSYQE 1289

Query: 1482 IERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEIT 1541
             E V++  EL+V   E   L + +  L K + E     ++ ++ L+N+  +   L ++  
Sbjct: 1290 KE-VQMKHELSVLENEHNILQENLDTLQKQVVELTVSASQKESELQNEVCKQEKLQEKAQ 1348

Query: 1542 NLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDL 1591
             L+       +KI +  + AS+ ++ +   L + +N + L A  ++E DL
Sbjct: 1349 KLEKDAGDLQAKILEISTLASE-REAQISSLKDEINSQHLKA-KQSEDDL 1396



 Score =  112 bits (269), Expect = 9e-23
 Identities = 201/1063 (18%), Positives = 444/1063 (41%), Gaps = 79/1063 (7%)

Query: 94   LANTLKQKEILMEKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKE 153
            L   L  +E L E+ ++ +++ +     IV                +   V+ L   +K+
Sbjct: 450  LQQELSHQETLREQTQELEKIKREELEGIVSELQAKIIEVSSIASEREACVSSLQYEMKD 509

Query: 154  KDNALSVLQVKMKI-METTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXE 212
            + +     +  ++  M+  + +LQE ++  +  I  K                      E
Sbjct: 510  QLSKAKQCEADLRNEMKEKVGNLQELLDAANHGIAEKEHHLESLNQSLKQMELLYCQKEE 569

Query: 213  D--TKQQMTKMQENFIAMEAEWKDEKQR----LLKDIESKDVRISSLEEANKLLEAARFE 266
            +    QQ  +  EN IA + +  DE Q+    L  + +    R+SSL+E     +    +
Sbjct: 570  EIIASQQAKEQLENNIAEQKQQLDEIQQNREILRNERDHLSTRVSSLQEEIHCSQQEFSD 629

Query: 267  ISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSI--EPSCEEKTEIEEKG-SLEIANMTE 323
            +  +H+ L ++L                   + +  +     +  + EK   LE     E
Sbjct: 630  LQTDHNVLKEKLVNLQNQLEQAMITASQKESELLLLQQELSHQETLREKALELEAIKREE 689

Query: 324  LTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMK 383
              KK++ L+    ++     + E ++ ++  E +     + +    + R+  +     +K
Sbjct: 690  FEKKVKELQDRILEVSTLASQREAQVISLENEMRDQQLSANQSKDNLCRE-WQEKLGILK 748

Query: 384  SPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXX 443
                 +S +  ++D   +    ++ ++EMV+    KD+++     +++D           
Sbjct: 749  GELDVVSRDAADKDHQLESLDQKLKEMEMVVLQKEKDVMETHQ--AKEDLEKRIAELEEC 806

Query: 444  GKDTLIAQLQLEHQQHMEGPSL---IHVGTNTE-DVNEIAKVQEQLKQELNDEIKDVNVK 499
             +   I + + +H    E  SL   IH   +T+    +   V E     L + +  +  K
Sbjct: 807  KQKLEIMRNERDHLS-TEVASLKEEIHSYQDTQMQKQQTISVLEVENNALKENMAALE-K 864

Query: 500  DLIEKLKSAEEQITQLNDEI-------DAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSD 552
             L E++ +A ++ ++L +++       + A +  I      + +++++Q  +   S ++ 
Sbjct: 865  QLAEEITTASQKNSELQNKLHQQESLHEKAQELEIGRHEEFERRVRELQAKVQEVSTLA- 923

Query: 553  SNKEIVR--LTEELH-HLSQKVAE------LEEEKGNLQLHL----VDYDSGRMIESDVY 599
            S KE V   L EEL  HL  KV+E      LEE+   LQ  +     D  S   +   + 
Sbjct: 924  SEKEAVAYSLQEELTGHLKAKVSEDDLRRVLEEKVETLQREIETASCDATSKDGLLQTLD 983

Query: 600  KKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEI 659
            +K+ +ME L + +  A+  +++ K DL +E++ L  K  E+E  L  +  ++ ++     
Sbjct: 984  QKLRQMEMLCQQKEDAVFEIQNSKEDLQKEMNELVSKNQELEGCLQHLEMVKKEKDLLSN 1043

Query: 660  KSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMD 719
            +   L+EQI+  S   K+     +  K+ +E++      LE+   D+  K + ++Q    
Sbjct: 1044 EVTSLKEQINDQSLRAKQSE--ADLCKVFEEKIETLQGQLESSSRDVSEK-EKHLQTLHQ 1100

Query: 720  LTDKLEKMSAEKISELLAKINHEE--QSKIQTQFGIDAKIQERDLYIENIESELSKYKSR 777
               +++ +  +K + +L   N +E  Q KI        +++     +E ++SE     + 
Sbjct: 1101 KVSQMDLLCQQKENAVLEMQNAKEDLQKKIDELVSEKQQLEGCLQNLEMVKSERDLLSTE 1160

Query: 778  ICRLEESIAVMEDRRYSLERKADQLGSYLQEKQK-------AYSEYTIQEDELVNRL--- 827
            +  +++    + D+    ++  D L   L+EK K         S    ++D+L+  L   
Sbjct: 1161 VTSIKDQ---LNDQDLKAKQSEDDLRKVLEEKIKNLQGQLETASRDVSEKDQLLQTLDQK 1217

Query: 828  AVLMDH-DRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRT 886
               MD   +  EK  L++    + L+K+   ++ E Q L+    +++    A     N  
Sbjct: 1218 VTQMDQLYKKKEKYALDLLQVKENLEKRIGEIIVEKQQLEGCQQNLETVSKAKDNLLNEL 1277

Query: 887  DLAESESTKYQTQLRDLESNLKRITHEHQTL---IVQKKKEIEDLEIEFNTQIESAIRDK 943
               + E   YQ +   ++  L  + +EH  L   +   +K++ +L +   +Q ES ++++
Sbjct: 1278 TSLKVEIQSYQEKEVQMKHELSVLENEHNILQENLDTLQKQVVELTVS-ASQKESELQNE 1336

Query: 944  KVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVE-ELNKMNLELIDKHVQKQQTQSPD 1002
                EK ++  + + +    LQ     I  L    E +++ +  E+  +H++ +Q++  D
Sbjct: 1337 VCKQEKLQEKAQKLEKDAGDLQAKILEISTLASEREAQISSLKDEINSQHLKAKQSED-D 1395

Query: 1003 YTEQYINEINKLNALLK-------QKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTT 1055
                +  +I  L   L+        KD+ +  LNQK+   +     +    E+ + +   
Sbjct: 1396 LLRVFEEKIENLQGQLEIARLDVSDKDQLLQTLNQKLKQME----ELCKQKETCVLEMHQ 1451

Query: 1056 KLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKET 1098
              E++E+++  V  Q   S+Q+ + L++L R++ D +K L +T
Sbjct: 1452 TKEDLEKKI--VELQADKSQQNQQNLEML-RQEKDHLKSLNQT 1491



 Score =  106 bits (254), Expect = 6e-21
 Identities = 192/1080 (17%), Positives = 461/1080 (42%), Gaps = 81/1080 (7%)

Query: 498  VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEI 557
            ++++  +L  AE+++ +L    ++A       K+  +L  K++ + +        ++KE 
Sbjct: 4    LRNVFSQLARAEQEVAKLTVVHESAQTEW---KNRKELLEKELNEAV--------THKEC 52

Query: 558  VRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIE-----SDVYKKMIEMENL-AET 611
              L+E++  L  K++ LE+E    Q        G ++E     S + KK  E+E L AE 
Sbjct: 53   --LSEQVLILQGKISVLEDELKKAQSQERGEVLGPIMELQESISHLEKKKAEVEALLAEE 110

Query: 612  RL---KAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQI 668
            R    K  + L+   FDL + ++ ++ + + +++ L    ++ S Q+ +  + V   +Q+
Sbjct: 111  RCSFEKETARLQLVVFDLEKSINSIRLERETLQEALKTQKEMLSAQISALERDVSRLQQV 170

Query: 669  DALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMS 728
            +    ++ +++    +L+  +E+L G +  L+     +  ++Q    E     D +  + 
Sbjct: 171  EVQLTAEIKISA---DLRQQREELEGKVASLDRMVHSLHAEIQGLEVERASQQDAINSL- 226

Query: 729  AEKISEL-LAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAV 787
               IS+L +A+   +E  K         K++E     + + +E +  K+  C +++ +  
Sbjct: 227  ---ISDLQIARATVQEYEK---------KLEEH----QKVVAENNSLKNEACTMQQELNN 270

Query: 788  MEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHE 847
                   L+ + ++L     E++   SE  ++ + L   +  L +   + ++++  +  E
Sbjct: 271  HLKAIGDLQAEVNELRFEKTEEENKVSEALVKIESLQTEILHLCEKISLKDEEIRNLTKE 330

Query: 848  NKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANR-TDLAESESTKYQTQLRDLE-- 904
             + +  + +++ E+N  +   +   ++ +   VEK  +    A S +++ Q Q+  L   
Sbjct: 331  YESVDNELKLVKEQNVEINAMIKSNRKEHEETVEKLQQELHCAASAASEKQEQMLVLSAE 390

Query: 905  -SNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQ 963
             ++LK     +     QK++E+  LE + N   E+    +  L E      +  ++    
Sbjct: 391  VTSLKEQICRYSENEAQKQQELSILEAQHNVLKENLTSLQNQLAEATTSASQKESEF-IL 449

Query: 964  LQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDE 1023
            LQ+  ++ E L    +EL K+  E ++  V + Q +  + +    +  ++  A +     
Sbjct: 450  LQQELSHQETLREQTQELEKIKREELEGIVSELQAKIIEVS----SIASEREACVSSLQY 505

Query: 1024 EIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQI 1083
            E   +  +++ A+     + ++ + K+      L+     +      L    Q  +++++
Sbjct: 506  E---MKDQLSKAKQCEADLRNEMKEKVGNLQELLDAANHGIAEKEHHLESLNQSLKQMEL 562

Query: 1084 LVREQDDQIKELKETKLTFEMNIPKTEGMI--ISSTIEPMSDDANNVDXXXXXXXXXXXX 1141
            L  +++++I   ++ K   E NI + +  +  I    E + ++ +++             
Sbjct: 563  LYCQKEEEIIASQQAKEQLENNIAEQKQQLDEIQQNREILRNERDHL-STRVSSLQEEIH 621

Query: 1142 LKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKS 1201
               QE  +   + +VL+E+   L  +L++      Q E+    L   ++ +QE + +   
Sbjct: 622  CSQQEFSDLQTDHNVLKEKLVNLQNQLEQAMITASQKES-ELLLLQQELSHQETLREKAL 680

Query: 1202 KLEQLNTEN-DNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQ 1260
            +LE +  E  +  +  + +    +S+   QR  ++  L +  +  ++    +++  L  +
Sbjct: 681  ELEAIKREEFEKKVKELQDRILEVSTLASQREAQVISL-ENEMRDQQLSANQSKDNLCRE 739

Query: 1261 LSAFESKYEQLLDSVQSSTQEETNKIVTMEQ-VTSLQNKLQDKEEHLRNLQEKYADVINQ 1319
                    +  LD V     ++ +++ +++Q +  ++  +  KE+ +    +   D+  +
Sbjct: 740  WQEKLGILKGELDVVSRDAADKDHQLESLDQKLKEMEMVVLQKEKDVMETHQAKEDLEKR 799

Query: 1320 IEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYK--QMQEQSILNINE-ENAQ 1376
            I    +E+E+ K                    L+ E  SY+  QMQ+Q  +++ E EN  
Sbjct: 800  I----AELEECKQKL-EIMRNERDHLSTEVASLKEEIHSYQDTQMQKQQTISVLEVENNA 854

Query: 1377 LKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFEN 1436
            LK++              +  A  K  EL ++L  ++S +++K  E  I    R++EFE 
Sbjct: 855  LKEN---MAALEKQLAEEITTASQKNSELQNKLHQQES-LHEKAQELEI---GRHEEFER 907

Query: 1437 VRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKIT 1496
              ++L    + +  L  EKE   A+      E   H +    E ++ RV L E++     
Sbjct: 908  RVRELQAKVQEVSTLASEKE---AVAYSLQEELTGHLKAKVSEDDLRRV-LEEKVETLQR 963

Query: 1497 ESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQK 1556
            E  + +      +  L+    K  +M+   + +E  +  + +   +LQ  +    SK Q+
Sbjct: 964  EIETASCDATSKDGLLQTLDQKLRQMEMLCQQKEDAVFEIQNSKEDLQKEMNELVSKNQE 1023



 Score = 92.3 bits (219), Expect = 1e-16
 Identities = 169/918 (18%), Positives = 386/918 (42%), Gaps = 56/918 (6%)

Query: 213  DTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKD---VRISSLEEANKLLEAARFEISL 269
            D   Q+  + +    ME     +++ +++  ++K+    RI+ LEE  + LE  R E   
Sbjct: 760  DKDHQLESLDQKLKEMEMVVLQKEKDVMETHQAKEDLEKRIAELEECKQKLEIMRNERDH 819

Query: 270  EHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSC--EEKTEIEEKGSLEIANMTELTKK 327
              +++A   E+              ++   +E +   E    +E++ + EI   ++   +
Sbjct: 820  LSTEVASLKEEIHSYQDTQMQKQQTISVLEVENNALKENMAALEKQLAEEITTASQKNSE 879

Query: 328  IELLEHLNCQIRQTNKELE-NKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPW 386
            ++   H    + +  +ELE  +        + + +  ++ S L S K     A  ++   
Sbjct: 880  LQNKLHQQESLHEKAQELEIGRHEEFERRVRELQAKVQEVSTLASEKEA--VAYSLQEEL 937

Query: 387  SQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKD 446
            +      +++D  +++ + ++  L+  I++ + D   K+ ++   D            K+
Sbjct: 938  TGHLKAKVSEDDLRRVLEEKVETLQREIETASCDATSKDGLLQTLDQKLRQMEMLCQQKE 997

Query: 447  TLIAQLQ-------------LEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEI 493
              + ++Q             +   Q +EG  L H+    ++ + ++     LK+++ND+ 
Sbjct: 998  DAVFEIQNSKEDLQKEMNELVSKNQELEG-CLQHLEMVKKEKDLLSNEVTSLKEQINDQS 1056

Query: 494  KDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDS 553
                  +  +  K  EE+I  L  ++++++++ +  K  H   L Q    +D   +  ++
Sbjct: 1057 LRAKQSEA-DLCKVFEEKIETLQGQLESSSRD-VSEKEKHLQTLHQKVSQMDLLCQQKEN 1114

Query: 554  NKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEM--ENLAET 611
               ++ +      L +K+ EL  EK  L+  L + +  +  E D+    +    + L + 
Sbjct: 1115 --AVLEMQNAKEDLQKKIDELVSEKQQLEGCLQNLEMVKS-ERDLLSTEVTSIKDQLNDQ 1171

Query: 612  RLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQS--DQVCSEIKSVHLEEQID 669
             LKA    +  +  L +++  LQ + +     +++  QL    DQ  +++  ++ +++  
Sbjct: 1172 DLKAKQSEDDLRKVLEEKIKNLQGQLETASRDVSEKDQLLQTLDQKVTQMDQLYKKKEKY 1231

Query: 670  ALSAS--KKELALVIENLKLDKEQLYGTIKDLEN---DKEDIMNKLQNYIQENMDLTDKL 724
            AL     K+ L   I  + ++K+QL G  ++LE     K++++N+L +   E     +K 
Sbjct: 1232 ALDLLQVKENLEKRIGEIIVEKQQLEGCQQNLETVSKAKDNLLNELTSLKVEIQSYQEKE 1291

Query: 725  EKMSAE-KISELLAKINHEEQSKIQTQF-GIDAKIQERDLYIENIESELSKYKSRICRLE 782
             +M  E  + E    I  E    +Q Q   +     +++  ++N   +  K + +  +LE
Sbjct: 1292 VQMKHELSVLENEHNILQENLDTLQKQVVELTVSASQKESELQNEVCKQEKLQEKAQKLE 1351

Query: 783  ESIA-----VMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDH-DRV 836
            +        ++E    + ER+A Q+ S   E    + +    ED+L+      +++    
Sbjct: 1352 KDAGDLQAKILEISTLASEREA-QISSLKDEINSQHLKAKQSEDDLLRVFEEKIENLQGQ 1410

Query: 837  VEKQLLEIEHENKELQKKNQIL--LEEN-QNLQISLSDMQQHYNALVEKANRTDLAESES 893
            +E   L++  +++ LQ  NQ L  +EE  +  +  + +M Q    L +K       +S+ 
Sbjct: 1411 LEIARLDVSDKDQLLQTLNQKLKQMEELCKQKETCVLEMHQTKEDLEKKIVELQADKSQQ 1470

Query: 894  TKYQTQ-LRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEK 952
             +   + LR  + +LK +    +      +K   +LE+    Q  S +  KK   +  E+
Sbjct: 1471 NQQNLEMLRQEKDHLKSLNQTIRRECEASRKIRAELELNVEEQTASILALKKASQQWEEQ 1530

Query: 953  NIEYVTQLEAQ---LQEYKNNIENLNMNVEELNKMNLEL--IDKHVQKQQTQSPDYTEQY 1007
            N E + QL+A+   ++ YK  +E    +     ++ LE   ++K +++    S    +  
Sbjct: 1531 NQELLEQLKAKTEAVEHYKAQVEKAMNHYNGKKQLLLEAQELNKTLEQSLEVSKREAKAL 1590

Query: 1008 INEINKLNALLKQKD--EEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQ 1065
              E+      L Q +  E+ +A   K   AQV +       + ++A     L   E    
Sbjct: 1591 ETELTLARMELNQANDKEKSLAAKVKTLEAQVDFADRQLREKRRIADDGEDLRQKENLYF 1650

Query: 1066 RVSKQLLDSKQHNEELQI 1083
            RV ++  D+   + E ++
Sbjct: 1651 RVPEKQQDTSADSLEFEL 1668


>UniRef50_UPI0000E7FDD2 Cluster: PREDICTED: similar to trans-Golgi
            p230; n=3; Gallus gallus|Rep: PREDICTED: similar to
            trans-Golgi p230 - Gallus gallus
          Length = 2202

 Score =  152 bits (368), Expect = 9e-35
 Identities = 302/1473 (20%), Positives = 619/1473 (42%), Gaps = 119/1473 (8%)

Query: 150  TIKEKDNALSVLQVKMKIMETTILDLQEKIN--EKDQIIEAKNKATTXXXXXXXXXXXXX 207
            +++EKD  +SVLQ ++ +++  + + Q  I   + +   E + ++ T             
Sbjct: 242  SLEEKDQLISVLQTQVSLLKQRLQNGQIGIELPDPNNQSEPQVQSQTKEINAENIVEPGN 301

Query: 208  XXXXEDTKQQMTKMQENFIAMEAEW-KDEKQRLLKDIESKDVRISSLEEANKLLEAARFE 266
                 +T  Q  K QEN +    E  +  K+R  +    K+     LEE  + LE  +  
Sbjct: 302  SVKTLETLNQRVKRQENLLQRCKEMIRSHKERCAQLTNEKEALQEQLEERLQELEKMKDL 361

Query: 267  ISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEI-ANMTELT 325
               E +KL  +L                +  ++ +    E  E++E+   ++ A + ++T
Sbjct: 362  HMGEKTKLITQLRDAKNLIEQLEQDKGMVIAET-KRQMHETLEMKEEEVAQLRARIKQIT 420

Query: 326  KK-IELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLIS--RKSGRNTASKM 382
             +  EL E      R   +ELE  L       +A      +    I    K+       +
Sbjct: 421  TQGEELKEQKEKFERAAFEELEKALGMAQRTEEARKKLQAEMDEKIKAVEKANEEERVNL 480

Query: 383  KSPWSQLSSETLNQDTDKKINKNEIAKLEMV--IQSLNKDL-VDKEYVISEKDTXXXXXX 439
            +   +++  E +  +  KK +++ +A+LE +   +   KD  +++     E++       
Sbjct: 481  QQELTRVKQEVV--EIMKKSSEDRVAELEKLHKEEMATKDQELNERLQAQEREFQEKMKA 538

Query: 440  XXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDV-NEIAKVQEQLKQELND------E 492
                 +   +  LQ + QQ  E  +L  +    + + +E  K  E++ QE+        E
Sbjct: 539  ALEKNQSECLKTLQEQEQQ--ESLALEELELQKKAIQSECDKKLEEMHQEVETFKTRILE 596

Query: 493  IKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKL---KQMQKTIDNFSK 549
            ++    K   +  K +EE  T +  E    NK +  +   HK +L   KQ Q+ +     
Sbjct: 597  LESSLAKCSQDDKKRSEELSTLMESEKKQHNKEVSDIVEKHKEELENVKQQQEKLWTEKL 656

Query: 550  VSDSNKEIVRLTEELHHLSQKVAELEEEKGNL-QLHLVDYDSGRMIESDVYKKMIEMENL 608
                 + ++ + +      Q++  + +EK  + + H+ + +   + + DV  K  E+E L
Sbjct: 657  QILQQQHVIEIEKMREKQEQEIDTILKEKETVFRTHIEEMNEKTLEKLDV--KQTELETL 714

Query: 609  AETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQI 668
            +    +A+ + +    DL QEL  L+ K  E + +     + + +Q   E++ +  E +I
Sbjct: 715  SSELSEALKVRQ----DLEQELSELKSKVGEAKQEFEGKLEAERNQHKEEVEIMLKEHEI 770

Query: 669  ---DALSASKKELALVIENLKLDKEQLYGTIKDLEND-KEDIMNKLQNYIQENMDLTDKL 724
               D     K+EL    ++L+ +KE+L    K  E + KE         +Q +  L +  
Sbjct: 771  SIQDVEKVLKEELNQTKQSLE-EKERLLEEAKTREQELKESAQRSEAELVQVSARLME-- 827

Query: 725  EKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDL--YIENIESELSKYKSRICRLE 782
              +S +  S   AK   EE +K+Q +  +D K ++  L   +   ES+L++ K+    LE
Sbjct: 828  ASLSQQNTSNEQAKQYEEELAKLQQKL-MDLKGEKLQLSEQLVRTESQLNEVKN---ELE 883

Query: 783  ESIAVMEDRRYSLERKADQLGSYLQEKQKAY-SEYTIQEDELVNRLAVLMDHDRVVEKQL 841
              I+ + + +  L+ ++D+    +    + Y S+    ++E       L + +  +E  +
Sbjct: 884  LYISQVHELKQQLQEQSDENTQKVMSLTQQYESQLKDLQEEADKAKQTLTERENDIE-HV 942

Query: 842  LEIEHENKELQKKNQILLEENQNLQISLSDMQQHY-NALVEKANRTDLAESESTK----Y 896
             ++++E  E  K+  +  EE       +S +Q  Y N L  + N+ +  + +S +    +
Sbjct: 943  KKVQNEEMEELKQKLLATEER------ISTLQGDYENKLKRQENKMEKMKQKSKEMQETF 996

Query: 897  QTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEY 956
            + +L + ES LK+     Q    QK+ E     +E      + I D      K E N + 
Sbjct: 997  KKKLAEQESKLKKELENKQLEFSQKESEFNAKMLEMAHASSAGINDAV---SKLESNQK- 1052

Query: 957  VTQLEAQLQEYKNNIENLNMNVE-ELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLN 1015
              QLE+  + +K  +E ++ + E +LN+   EL +KH  + Q +  +  +    ++   +
Sbjct: 1053 -EQLESLAEAHKRELEEISRSWEKKLNQQAEELQEKHEMELQEKEQELGD-LKEKLATFS 1110

Query: 1016 ALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEE----EMQRVSKQL 1071
            A  +    EI  L ++      +   +  + +  LAQ +  L N E     ++Q++   L
Sbjct: 1111 AEKEGSRTEITRLKEEQVKRNETLKQLQEELKQSLAQMSA-LSNSESGLKAQLQKLEGDL 1169

Query: 1072 LDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXX 1131
              S +    LQ  +  Q   I+E  + ++T   +  KT    + +     S D  N +  
Sbjct: 1170 SQSLKEKSGLQEQISRQ-KAIEEKDKARITELADKLKTLEEKLQTLQSSHSKDRENYEKK 1228

Query: 1132 XXXXXXXXXXLK--VQEEEEFIQERSVLQEQSAKLNTELQECYTK--IIQLETLNTELTG 1187
                      +K  V + + + +   VL +   K N  +++C  K  I+  +  + E   
Sbjct: 1229 IEAFQLQETEVKELVAQLDAYWKSAEVLLQ--TKSNELIEKCNEKIGIVTCKIADCERQA 1286

Query: 1188 HDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQRE 1247
               V +  I ++   ++QL  E DN++ +   +R  I   V ++     +L K+   Q++
Sbjct: 1287 -TKVKEAVIIKMNKSVQQLQ-EKDNVIKS---MRDDIEGLVTEK----EQLQKEGGHQKQ 1337

Query: 1248 ADFQKTEHELRV-QLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHL 1306
            A    TE E  + QL    S+    + S++   QE+ ++I T+ +     N+L  + E +
Sbjct: 1338 A---ATEKETCITQLRKELSENINAVTSLREDLQEKESEISTLNKTI---NELNVRLESM 1391

Query: 1307 RNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQS 1366
             +L EK A     I +L ++ ++E++                  +L +  +  +Q +  +
Sbjct: 1392 VSLTEKEA----AISLLSTQHQEERLQL-----------INQVQELSSSVELLRQEKASA 1436

Query: 1367 ILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTIT 1426
            +  ++   A+L +               + D ++K LE+++    K  E   K  E    
Sbjct: 1437 LEQVDHCTAKLSEWKTKAQTRFTQNHEAIKDLQSK-LEVSNTQATKKGEELDKLKE---E 1492

Query: 1427 LTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVK 1486
            L Q+  + ++++  L E E RIE    E  +EL I   ++ E   H    QK SE + +K
Sbjct: 1493 LAQQGKDLDSLKSVLEEKENRIEKQESELTAELKIQAARVAELEEH--IAQKTSENDSLK 1550

Query: 1487 LIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNM 1546
              EEL  +  E   + ++  E+ + L++      E  + L+  E +++ L +EI +L+  
Sbjct: 1551 --EELK-RYHEQKDMEQK--EVARQLQQAEKVAFEKDSRLKEAEEKVLNLENEIGSLKAE 1605

Query: 1547 VRASSSKIQKHVSFASDTKQGRDEQLDNTMNKE 1579
              A   +  +  S    +K+   ++L+  +N E
Sbjct: 1606 CEAKEREFDQMKSAILKSKEEELKELEERLNAE 1638



 Score =  144 bits (350), Expect = 1e-32
 Identities = 281/1431 (19%), Positives = 588/1431 (41%), Gaps = 120/1431 (8%)

Query: 97   TLKQKEILMEKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDN 156
            +L++KE L+E+ K  ++  K S+    R                L      +   K+ + 
Sbjct: 789  SLEEKERLLEEAKTREQELKESAQ---RSEAELVQVSARLMEASLSQQNTSNEQAKQYEE 845

Query: 157  ALSVLQVKMKIMETTILDLQEK-INEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTK 215
             L+ LQ K+  ++   L L E+ +  + Q+ E KN+                    E+T+
Sbjct: 846  ELAKLQQKLMDLKGEKLQLSEQLVRTESQLNEVKNELELYISQVHELKQQLQEQSDENTQ 905

Query: 216  QQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLA 275
            + M+  Q+     E++ KD ++   K  ++   R + +E   K+      E  L+   LA
Sbjct: 906  KVMSLTQQ----YESQLKDLQEEADKAKQTLTERENDIEHVKKVQNEEMEE--LKQKLLA 959

Query: 276  QELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLN 335
             E  +                +  +E   ++  E++E    ++A      KK   LE+  
Sbjct: 960  TE--ERISTLQGDYENKLKRQENKMEKMKQKSKEMQETFKKKLAEQESKLKKE--LENKQ 1015

Query: 336  CQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLS---SE 392
             +  Q   E   K+  M   S A  + +        ++   + A   K    ++S    +
Sbjct: 1016 LEFSQKESEFNAKMLEMAHASSAGINDAVSKLESNQKEQLESLAEAHKRELEEISRSWEK 1075

Query: 393  TLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVIS-EKD---TXXXXXXXXXXGKDTL 448
             LNQ  ++   K+E+ +L+   Q L  DL +K    S EK+   T           ++  
Sbjct: 1076 KLNQQAEELQEKHEM-ELQEKEQELG-DLKEKLATFSAEKEGSRTEITRLKEEQVKRNET 1133

Query: 449  IAQLQLEHQQHMEGPSLIH-------------VGTNTEDVNEIAKVQEQLKQELNDEIKD 495
            + QLQ E +Q +   S +               G  ++ + E + +QEQ+ ++   E KD
Sbjct: 1134 LKQLQEELKQSLAQMSALSNSESGLKAQLQKLEGDLSQSLKEKSGLQEQISRQKAIEEKD 1193

Query: 496  -VNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLK---LKQMQKTIDNFSKVS 551
               + +L +KLK+ EE++  L        +N  K     +L+   +K++   +D + K +
Sbjct: 1194 KARITELADKLKTLEEKLQTLQSSHSKDRENYEKKIEAFQLQETEVKELVAQLDAYWKSA 1253

Query: 552  D------SNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEM 605
            +      SN+ I +  E++  ++ K+A+ E +   ++  ++     +M +S   +++ E 
Sbjct: 1254 EVLLQTKSNELIEKCNEKIGIVTCKIADCERQATKVKEAVII----KMNKS--VQQLQEK 1307

Query: 606  ENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVH-- 663
            +N+ ++    I  L ++K  L +E    +Q   E E  +  + +  S+ + + + S+   
Sbjct: 1308 DNVIKSMRDDIEGLVTEKEQLQKEGGHQKQAATEKETCITQLRKELSENI-NAVTSLRED 1366

Query: 664  ---LEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDL 720
                E +I  L+ +  EL + +E++ +   +    I  L    ++   +L N +QE    
Sbjct: 1367 LQEKESEISTLNKTINELNVRLESM-VSLTEKEAAISLLSTQHQEERLQLINQVQELSSS 1425

Query: 721  TDKL--EKMSA-EKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSR 777
             + L  EK SA E++    AK++ E ++K QT+F      Q  +  I++++S+L    ++
Sbjct: 1426 VELLRQEKASALEQVDHCTAKLS-EWKTKAQTRF-----TQNHEA-IKDLQSKLEVSNTQ 1478

Query: 778  ICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVV 837
              +  E +  +++      +  D L S L+EK+    +   QE EL   L +       +
Sbjct: 1479 ATKKGEELDKLKEELAQQGKDLDSLKSVLEEKENRIEK---QESELTAELKIQAARVAEL 1535

Query: 838  EKQLLEIEHENKELQKKNQILLEENQNLQISLS-DMQQHYNALVEKANRTDLAESESTKY 896
            E+ + +   EN  L+++ +   E+    Q  ++  +QQ      EK +R   AE +    
Sbjct: 1536 EEHIAQKTSENDSLKEELKRYHEQKDMEQKEVARQLQQAEKVAFEKDSRLKEAEEKVLNL 1595

Query: 897  QTQLRDLESNLKRITHEHQ----TLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEK 952
            + ++  L++  +    E       ++  K++E+++LE   N +    + D K   E+   
Sbjct: 1596 ENEIGSLKAECEAKEREFDQMKSAILKSKEEELKELEERLNAENSCKLADLKKKAEQKIG 1655

Query: 953  NI--EYVTQLEAQLQEYK----NNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQ 1006
            +I  E V Q+E + Q+ K    N + +L   V+E  +  +E +++ + K    S +   +
Sbjct: 1656 SIKRELVRQMEEKEQQLKQDRENQVRHLEQKVQE-REAKIESLEEKM-KSVRDSTELERE 1713

Query: 1007 YINEINKLNALLKQKDEEIIALNQ-----KINNAQ---VSYMSMVSDYESKLAQFTTKLE 1058
             + +I    A ++Q+  E+I   Q     KIN  Q   +    ++  YES+  +    L 
Sbjct: 1714 MLQKIESTKAAVEQEKNEVIKSVQQTHEEKINKLQKDLIEKNKLLQKYESEQREGIDSLL 1773

Query: 1059 NMEEEMQRVSKQL-LDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISST 1117
             ++ + + + K+L    K+H EE  +    +++  ++ K+  L  + +    E       
Sbjct: 1774 ELQSKQEELLKKLECAEKRHREEQSVTEGLREELEEQAKKYSLLVDEHARCGE-----QK 1828

Query: 1118 IEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKI-- 1175
            ++ + D+   V+            LK +E  + +Q++  L+E++ +L    +    K   
Sbjct: 1829 VKELEDNLAKVNEVHKTELEDRS-LKYEENLKSLQQQ--LEERNDRLKAFEENAEEKAKS 1885

Query: 1176 -IQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFE 1234
             ++L+ L  ++       Q ++ + + + ++L  + ++L   +  LR      +D    E
Sbjct: 1886 GLELQKLLGDMQNQQKDLQAKLEEAEREKQKLRKDVNSLQKDLRTLRKEHQQELDIVKKE 1945

Query: 1235 IAELWKQHLAQREADFQ--------KTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKI 1286
              E  +Q +   + D +        +   E   QL+  E + E  +    S  QE  +++
Sbjct: 1946 SLEEMEQKIRCEQEDIELKHSSTLKQLMREFNTQLAQKEMELETAVKETISKAQEVESEL 2005

Query: 1287 VTMEQV--TSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXX 1344
            +   Q+  T L  K+ +K++ L+   +KY +++   E   +    E              
Sbjct: 2006 IENHQIETTQLHKKIAEKDDDLKRTVKKYEEILEAREEEMTTKVHELQTQLEELQKEYKQ 2065

Query: 1345 XXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLE 1404
                     +EN +  ++Q Q        N   K               R+ + E K+  
Sbjct: 2066 RMAEKDHRNSENVTIAELQAQLAQKTTLVNDS-KLKEQEFKEQIHVLEDRLKNYEKKMYV 2124

Query: 1405 LTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEK 1455
             +     +D  +    H   ++L     EFE +R+ L EY    E  T  K
Sbjct: 2125 TSVGTPYRDGNL----HHTDVSLFGEPTEFEYLRKVLFEYMMGRETKTMAK 2171



 Score =  142 bits (344), Expect = 7e-32
 Identities = 303/1494 (20%), Positives = 608/1494 (40%), Gaps = 117/1494 (7%)

Query: 154  KDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXED 213
            +D    + ++  + M T   +L E++  +++  + K KA                   E 
Sbjct: 500  EDRVAELEKLHKEEMATKDQELNERLQAQEREFQEKMKAALEKNQSECLKTLQEQEQQES 559

Query: 214  TKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSK 273
               +  ++Q+  I  E + K E+    +++E+   RI  LE +         + S E S 
Sbjct: 560  LALEELELQKKAIQSECDKKLEEMH--QEVETFKTRILELESSLAKCSQDDKKRSEELST 617

Query: 274  L--AQELEQXXXXXXXXXXXXXXL--AKQSIEPSCEEKTEI-EEKGSLEIANMTELTKK- 327
            L  +++ +               L   KQ  E    EK +I +++  +EI  M E  ++ 
Sbjct: 618  LMESEKKQHNKEVSDIVEKHKEELENVKQQQEKLWTEKLQILQQQHVIEIEKMREKQEQE 677

Query: 328  IE-LLEH----LNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKM 382
            I+ +L+         I + N++   KL    TE + +SS   +   L  R+      S++
Sbjct: 678  IDTILKEKETVFRTHIEEMNEKTLEKLDVKQTELETLSSELSEA--LKVRQDLEQELSEL 735

Query: 383  KSPWSQLSSETLNQ-DTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXX 441
            KS   +   E   + + ++  +K E+   E++++     + D E V+ E+          
Sbjct: 736  KSKVGEAKQEFEGKLEAERNQHKEEV---EIMLKEHEISIQDVEKVLKEE---LNQTKQS 789

Query: 442  XXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQE-QLKQE--LNDEIK--DV 496
               K+ L+ + +   Q+  E        +  E V   A++ E  L Q+   N++ K  + 
Sbjct: 790  LEEKERLLEEAKTREQELKESAQR----SEAELVQVSARLMEASLSQQNTSNEQAKQYEE 845

Query: 497  NVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSN-K 555
             +  L +KL   + +  QL++++      + +VK+  +L + Q+ +      + SD N +
Sbjct: 846  ELAKLQQKLMDLKGEKLQLSEQLVRTESQLNEVKNELELYISQVHELKQQLQEQSDENTQ 905

Query: 556  EIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKA 615
            +++ LT++      ++ +L+EE    +  L + ++   IE     +  EME L +  L  
Sbjct: 906  KVMSLTQQYE---SQLKDLQEEADKAKQTLTEREND--IEHVKKVQNEEMEELKQKLLAT 960

Query: 616  ISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASK 675
               + + + D   +L   + K ++++ K  ++ +    ++  +   +  E +   L  S+
Sbjct: 961  EERISTLQGDYENKLKRQENKMEKMKQKSKEMQETFKKKLAEQESKLKKELENKQLEFSQ 1020

Query: 676  KEL---ALVIENLKLDKEQLYGTIKDLE-NDKEDIMNKLQNYIQENMDLTDKLEKMSAEK 731
            KE    A ++E        +   +  LE N KE + +  + + +E  +++   EK   ++
Sbjct: 1021 KESEFNAKMLEMAHASSAGINDAVSKLESNQKEQLESLAEAHKRELEEISRSWEKKLNQQ 1080

Query: 732  ISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDR 791
              EL  K   E Q K Q    +  K+       E   +E+++ K    +  E++  +++ 
Sbjct: 1081 AEELQEKHEMELQEKEQELGDLKEKLATFSAEKEGSRTEITRLKEEQVKRNETLKQLQEE 1140

Query: 792  RYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENK-- 849
               L++   Q+ +    +    ++    E +L   L         + +Q   IE ++K  
Sbjct: 1141 ---LKQSLAQMSALSNSESGLKAQLQKLEGDLSQSLKEKSGLQEQISRQKA-IEEKDKAR 1196

Query: 850  --ELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNL 907
              EL  K + L E+ Q LQ S S  +++Y   +E      L E+E  +   QL     + 
Sbjct: 1197 ITELADKLKTLEEKLQTLQSSHSKDRENYEKKIEAFQ---LQETEVKELVAQLDAYWKSA 1253

Query: 908  KRITHEHQTLIVQKKKE-IEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQE 966
            + +       +++K  E I  +  +       A + K+ +  K  K+++ + + +  ++ 
Sbjct: 1254 EVLLQTKSNELIEKCNEKIGIVTCKIADCERQATKVKEAVIIKMNKSVQQLQEKDNVIKS 1313

Query: 967  YKNNIENLNMNVEELNKMNLELIDKHVQKQQ--TQSPDYTEQYINEINKLNALLKQKDEE 1024
             +++IE L    E+L K          +K+   TQ      + IN +  L   L++K+ E
Sbjct: 1314 MRDDIEGLVTEKEQLQKEGGHQKQAATEKETCITQLRKELSENINAVTSLREDLQEKESE 1373

Query: 1025 IIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSK-QLLDSKQH--NEEL 1081
            I  LN+ IN   V   SMVS  E + A      ++ EE +Q +++ Q L S      +E 
Sbjct: 1374 ISTLNKTINELNVRLESMVSLTEKEAAISLLSTQHQEERLQLINQVQELSSSVELLRQEK 1433

Query: 1082 QILVREQDDQIKELKETKLTFEMNIPKTEGMI--ISSTIE-------PMSDDANNVDXXX 1132
               + + D    +L E K   +    +    I  + S +E          ++ + +    
Sbjct: 1434 ASALEQVDHCTAKLSEWKTKAQTRFTQNHEAIKDLQSKLEVSNTQATKKGEELDKLKEEL 1493

Query: 1133 XXXXXXXXXLK--VQEEEEFIQER-----SVLQEQSAKLNTELQE-CYTKIIQLETLNTE 1184
                     LK  ++E+E  I+++     + L+ Q+A++  EL+E    K  + ++L  E
Sbjct: 1494 AQQGKDLDSLKSVLEEKENRIEKQESELTAELKIQAARV-AELEEHIAQKTSENDSLKEE 1552

Query: 1185 LTGH----DVVNQEQINQLKSKLEQLNTENDNLLSTVAE----LRSSISS---AVDQRGF 1233
            L  +    D+  +E   QL+ + E++  E D+ L    E    L + I S     + +  
Sbjct: 1553 LKRYHEQKDMEQKEVARQLQ-QAEKVAFEKDSRLKEAEEKVLNLENEIGSLKAECEAKER 1611

Query: 1234 EIAELWKQHLAQREADFQKTEHELRVQ----LSAFESKYEQLLDSV------QSSTQEET 1283
            E  ++    L  +E + ++ E  L  +    L+  + K EQ + S+      Q   +E+ 
Sbjct: 1612 EFDQMKSAILKSKEEELKELEERLNAENSCKLADLKKKAEQKIGSIKRELVRQMEEKEQQ 1671

Query: 1284 NKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILR---SEIEDEKVAFXXXXXX 1340
             K     QV  L+ K+Q++E  + +L+EK   V +  E+ R    +IE  K A       
Sbjct: 1672 LKQDRENQVRHLEQKVQEREAKIESLEEKMKSVRDSTELEREMLQKIESTKAAVEQEKNE 1731

Query: 1341 XXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLK--KSSXXXXXXXXXXXXRVNDA 1398
                      +    N+  K + E++ L    E+ Q +   S             ++  A
Sbjct: 1732 VIKSVQQTHEE--KINKLQKDLIEKNKLLQKYESEQREGIDSLLELQSKQEELLKKLECA 1789

Query: 1399 EAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLV-EYEKRIEDLTYEKES 1457
            E +  E     E    E+ ++  +Y++ +    DE     +Q V E E  +  +    ++
Sbjct: 1790 EKRHREEQSVTEGLREELEEQAKKYSLLV----DEHARCGEQKVKELEDNLAKVNEVHKT 1845

Query: 1458 ELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVA 1517
            EL    LK  EN    +  Q E   +R+K  EE       +    K   EL K L +   
Sbjct: 1846 ELEDRSLKYEENLKSLQ-QQLEERNDRLKAFEE------NAEEKAKSGLELQKLLGDMQN 1898

Query: 1518 KTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQ 1571
            +  ++Q  LE  E E   L  ++ +LQ  +R    + Q+ +           EQ
Sbjct: 1899 QQKDLQAKLEEAEREKQKLRKDVNSLQKDLRTLRKEHQQELDIVKKESLEEMEQ 1952



 Score =  122 bits (293), Expect = 1e-25
 Identities = 198/963 (20%), Positives = 408/963 (42%), Gaps = 82/963 (8%)

Query: 657  SEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMN---KLQNY 713
            S+I+S   E   +A S SK++L   +  ++       G   +L +  + I     KLQ  
Sbjct: 147  SDIESETEEVSGNADSLSKEQLLQRLRRMERSLGNYRGKYAELVSAYQVIQREKKKLQGI 206

Query: 714  IQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSK 773
            + ++ D        +  +I EL  ++  ++Q+K   Q   DA ++E+D  I  +++++S 
Sbjct: 207  LSQSQD-------KALRRIGELREELQMDQQAKKHLQEEFDASLEEKDQLISVLQTQVSL 259

Query: 774  YKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDH 833
             K R+   +  I + +    S      Q+ S  +E     +E  ++    V  L  L   
Sbjct: 260  LKQRLQNGQIGIELPDPNNQS----EPQVQSQTKE---INAENIVEPGNSVKTLETLNQR 312

Query: 834  DRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESES 893
             +  E  L   +   +  +++   L  E + LQ  L +  Q     +EK    DL   E 
Sbjct: 313  VKRQENLLQRCKEMIRSHKERCAQLTNEKEALQEQLEERLQE----LEKMK--DLHMGEK 366

Query: 894  TKYQTQLRDLESNLKRITHEHQTLIVQKKKEI-EDLEIEFNTQIESAIRDKKVLNEKYEK 952
            TK  TQLRD ++ ++++  +   +I + K+++ E LE++     +   R K++  +  E 
Sbjct: 367  TKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEVAQLRARIKQITTQGEEL 426

Query: 953  NIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELID--KHVQKQQTQSPDYTEQYINE 1010
              +      A  +E +  +       E   K+  E+ +  K V+K   +     +Q +  
Sbjct: 427  KEQKEKFERAAFEELEKALGMAQRTEEARKKLQAEMDEKIKAVEKANEEERVNLQQELTR 486

Query: 1011 I-NKLNALLKQKDEEIIALNQKINNAQVSY--MSMVSDYESKLAQFTTKLE-NMEEEMQR 1066
            +  ++  ++K+  E+ +A  +K++  +++     +    +++  +F  K++  +E+    
Sbjct: 487  VKQEVVEIMKKSSEDRVAELEKLHKEEMATKDQELNERLQAQEREFQEKMKAALEKNQSE 546

Query: 1067 VSKQLLDSKQHN----EELQI----LVREQDDQIKELKETKLTFEMNIPKTEGMI----- 1113
              K L + +Q      EEL++    +  E D +++E+ +   TF+  I + E  +     
Sbjct: 547  CLKTLQEQEQQESLALEELELQKKAIQSECDKKLEEMHQEVETFKTRILELESSLAKCSQ 606

Query: 1114 --------ISSTIEPMSDDAN-NVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKL 1164
                    +S+ +E      N  V             +K Q+E+ + ++  +LQ+Q    
Sbjct: 607  DDKKRSEELSTLMESEKKQHNKEVSDIVEKHKEELENVKQQQEKLWTEKLQILQQQHV-- 664

Query: 1165 NTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSK-LEQLNTENDNLLSTVAELRSS 1223
              E+++   K  Q + ++T L   + V +  I ++  K LE+L+ +   L +  +EL  +
Sbjct: 665  -IEIEKMREK--QEQEIDTILKEKETVFRTHIEEMNEKTLEKLDVKQTELETLSSELSEA 721

Query: 1224 ISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEET 1283
            +    D    E++EL K  + + + +F   E +L  + +  + + E +L   + S Q+  
Sbjct: 722  LKVRQDLEQ-ELSEL-KSKVGEAKQEF---EGKLEAERNQHKEEVEIMLKEHEISIQDVE 776

Query: 1284 NKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXX 1343
               V  E++   +  L++KE  L   + +  ++    +  RSE E  +V+          
Sbjct: 777  K--VLKEELNQTKQSLEEKERLLEEAKTREQELKESAQ--RSEAELVQVSARLMEASLSQ 832

Query: 1344 XXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVL 1403
                     + E +  K   +Q ++++  E  QL +               +    ++V 
Sbjct: 833  QNTSNEQAKQYEEELAK--LQQKLMDLKGEKLQLSEQLVRTESQLNEVKNELELYISQVH 890

Query: 1404 ELTHQLELKDSEIYQK----THEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESEL 1459
            EL  QL+ +  E  QK    T +Y   L    +E +  +Q L E E  IE +   +  E+
Sbjct: 891  ELKQQLQEQSDENTQKVMSLTQQYESQLKDLQEEADKAKQTLTERENDIEHVKKVQNEEM 950

Query: 1460 AILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAE-LNKALEEEVAK 1518
              L+ K+        T+Q + E  ++K  E    K+ +    +K++ E   K L E+ +K
Sbjct: 951  EELKQKLLATEERISTLQGDYE-NKLKRQEN---KMEKMKQKSKEMQETFKKKLAEQESK 1006

Query: 1519 TNEMQTALENQEIEIVTLNDEI-TNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMN 1577
               ++  LEN+++E      E    +  M  ASS+ I   VS     ++ + E L     
Sbjct: 1007 ---LKKELENKQLEFSQKESEFNAKMLEMAHASSAGINDAVSKLESNQKEQLESLAEAHK 1063

Query: 1578 KEL 1580
            +EL
Sbjct: 1064 REL 1066


>UniRef50_A2FU34 Cluster: Putative uncharacterized protein; n=1;
            Trichomonas vaginalis G3|Rep: Putative uncharacterized
            protein - Trichomonas vaginalis G3
          Length = 1504

 Score =  151 bits (367), Expect = 1e-34
 Identities = 200/913 (21%), Positives = 425/913 (46%), Gaps = 89/913 (9%)

Query: 476  NEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQIT--QLNDEIDAANKNMIKVKSNH 533
            N++   + +L+  LN  ++ +   +  E     ++ ++  +  DE+ A N  + K     
Sbjct: 358  NQLNDDKHRLQSLLNITLQKMKGDNPSEDTNFTDDMLSLQRERDELFAKNSYLEKQLQRE 417

Query: 534  KLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRM 593
            K+   ++    +  S    ++K I  L +        +A ++E +        D ++   
Sbjct: 418  KIHSTKLMAASEIESSTVPADKNIDDLWK------MYIAVVKENENRRDKEREDMETIVQ 471

Query: 594  IESDVY-KKMIEMEN--LAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQL 650
            +++D+  KK +E +N  L++T +K  + L + K  L+Q+++  +  +++V   L ++++L
Sbjct: 472  MKNDLENKKQLERDNDELSKTVIKLQNELNANKV-LMQKINS-ELGFEKVVKMLNNLTEL 529

Query: 651  QSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKL 710
             S+    E+  V L+E+   L     +    IE LK D E L   IK+ ++   +    L
Sbjct: 530  VSNDDKEEL--VQLKEENKNLKTKNDKSKAKIEKLKKDLEDLKQEIKESQSKHGE---NL 584

Query: 711  QNYIQENMDLTDKLEKMSAE--KISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIE 768
            QN I+ N D+++KL +++AE  K++ +L      +QS  Q Q    A +Q  +  ++N  
Sbjct: 585  QNMIENNKDISNKLNQLTAENAKLNSILQNYEKLKQSNSQLQNDYTA-LQNNNNQLQNNI 643

Query: 769  SEL-SKYKSRICR---LEESIAVMEDRR-------YSLERKADQLGSYLQEKQKAY---- 813
            S+L +K +S       L + ++ M D+        + L+     L S LQEK   Y    
Sbjct: 644  SQLKAKIESADANSKNLSDQLSKMRDQNEYLIKQNHQLDNNISVLESKLQEKDNLYKNLS 703

Query: 814  ---SEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLS 870
               S+   Q D+ +NR + L +  +  EK+L +++ + ++L K+N+ L  EN  +  SL 
Sbjct: 704  EQLSKQKSQNDDFLNRTSSLENQKQNYEKELKDLKDKLEDLNKQNKALKNENDKMVTSLH 763

Query: 871  DMQQHYNALVEKANRTD---------LAESES-TKYQTQLRDLESNLKRITHEHQTLIVQ 920
            +M+   ++L  K   +D         L+ S S ++   QL+DL  N ++ T      +  
Sbjct: 764  NMETAKSSLEGKLEISDNMVKSLKDQLSNSSSISQSNKQLQDLYENERKETKALNEKMAA 823

Query: 921  KKKEIEDLEIEF-NTQIE-SAIRDKKVL----NEKY----EKNIEYVTQLEAQLQEYKNN 970
             K+++  LE++  NT+ E   ++++ ++    N+K     +K    V +LE  L++ K +
Sbjct: 824  LKQQMSLLEVKLHNTEAEGEKMKNENLMLKSENDKLKSDSDKTASQVEKLEKDLKKSKKD 883

Query: 971  IENLNMNVEELNKMN----LELIDKH-VQKQQTQSPDYTEQYINEINKLNAL---LKQKD 1022
            +  L  + E+++  N     ++ DK+ ++ + T+     EQY N+  K + +   LK K 
Sbjct: 884  LSQLESDFEKISAENESLQKKIADKNKLKNETTEKSTLLEQYKNDNKKKDEIINQLKDKK 943

Query: 1023 EEIIALN-QKINNAQ---VSYMSMVSDY---ESKLAQFTTKLENMEEEMQRVSKQLL--- 1072
            ++I   N Q  NN Q   V   S+  D    ++ L +    L+  + ++Q+++ + +   
Sbjct: 944  KKIKQENEQNKNNLQKVTVENTSLQKDLQKSQNDLQKSQNDLQKSQNDLQKLTTENVNLQ 1003

Query: 1073 -DSKQHNEELQILVREQD--DQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVD 1129
             D ++   +LQ L +E++   +  E K T++  +    +     + S  E +  D N + 
Sbjct: 1004 KDLQKVQSDLQKLQQEREKLQENMENKNTQMKGDFEKIRANYDKLKSDYEKLKSDNNQLQ 1063

Query: 1130 XXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHD 1189
                         + + +   +Q +++ ++QS+  ++E+Q    ++ Q++  N  L  + 
Sbjct: 1064 KEADENKQKLDKKEEKIQNLKLQIQNLQKDQSSMKSSEIQRLQNELEQMKANNKSLKENI 1123

Query: 1190 VVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREAD 1249
                ++I Q K K + L +   NL + + E++++++    +      +L +  LA +  +
Sbjct: 1124 EAKNKEIEQNKEKNKALKSNLTNLQNKINEIQNALTGKDKEN-----QLLQNELANKNKE 1178

Query: 1250 FQKTEHELRVQLSAFESKYEQLLDSVQSSTQE-ETNKIVTMEQVTSLQ---NKLQDKEEH 1305
             QK + +L    S       ++ D + S  ++    K   ++Q  +LQ    KL+ + E 
Sbjct: 1179 IQKLKDDLEKAKSDKNKSQNEITDKLNSKLEKVMAEKEDLLKQNANLQAEMQKLKAENEK 1238

Query: 1306 LRNLQEKYADVIN 1318
            L+ + +K    IN
Sbjct: 1239 LKGILKKKTAYIN 1251



 Score =  133 bits (321), Expect = 4e-29
 Identities = 204/1127 (18%), Positives = 483/1127 (42%), Gaps = 72/1127 (6%)

Query: 458  QHMEGPSLIHVGTNTEDVNEIAKVQEQLKQ---ELNDEIKDVNVKDLI-EKLKSAEEQIT 513
            Q  E  S   + T +  + E+  V + ++    E N +I    ++ L  E+L+   +++ 
Sbjct: 288  QKKEYLSNAKLDTISRQIRELRAVADNIQDDVIEANRKIDQNKIQVLTREQLEEENKRLN 347

Query: 514  QLNDEIDAANK--NMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKV 571
                ++D++N   N  K +    L +   +   DN S+ ++   +++ L  E   L  K 
Sbjct: 348  LEKSQLDSSNNQLNDDKHRLQSLLNITLQKMKGDNPSEDTNFTDDMLSLQRERDELFAKN 407

Query: 572  AELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELH 631
            + LE++    ++H     +   IES        +++L +  +  +   E+++    +++ 
Sbjct: 408  SYLEKQLQREKIHSTKLMAASEIESSTVPADKNIDDLWKMYIAVVKENENRRDKEREDME 467

Query: 632  ILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKE- 690
             + Q  +++E+K     QL+ D    E+    ++ Q + L+A+K  +  +   L  +K  
Sbjct: 468  TIVQMKNDLENK----KQLERDN--DELSKTVIKLQ-NELNANKVLMQKINSELGFEKVV 520

Query: 691  QLYGTIKDL--ENDKEDIMN---KLQNYIQENMDLTDKLEKMSAE------KISELLAKI 739
            ++   + +L   +DKE+++    + +N   +N     K+EK+  +      +I E  +K 
Sbjct: 521  KMLNNLTELVSNDDKEELVQLKEENKNLKTKNDKSKAKIEKLKKDLEDLKQEIKESQSKH 580

Query: 740  NHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKA 799
                Q+ I+    I  K+ +       + S L  Y+    +L++S + +++   +L+   
Sbjct: 581  GENLQNMIENNKDISNKLNQLTAENAKLNSILQNYE----KLKQSNSQLQNDYTALQNNN 636

Query: 800  DQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILL 859
            +QL + + + +            L ++L+ + D +  + KQ  ++++    L+ K    L
Sbjct: 637  NQLQNNISQLKAKIESADANSKNLSDQLSKMRDQNEYLIKQNHQLDNNISVLESK----L 692

Query: 860  EENQNLQISLSD-MQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLI 918
            +E  NL  +LS+ + +  +   +  NRT   E++   Y+ +L+DL+  L+ +  +++ L 
Sbjct: 693  QEKDNLYKNLSEQLSKQKSQNDDFLNRTSSLENQKQNYEKELKDLKDKLEDLNKQNKALK 752

Query: 919  VQKKKEIEDLE----IEFNTQIESAIRDKKVLNEKYE-KNIEYVTQLEAQLQE-YKNNIE 972
             +  K +  L      + + + +  I D  V + K +  N   ++Q   QLQ+ Y+N  +
Sbjct: 753  NENDKMVTSLHNMETAKSSLEGKLEISDNMVKSLKDQLSNSSSISQSNKQLQDLYENERK 812

Query: 973  NLNMNVEELN--KMNLELIDKHVQKQQTQSPDYTEQYI---NEINKLNALLKQKDEEIIA 1027
                  E++   K  + L++  +   + +      + +   +E +KL +   +   ++  
Sbjct: 813  ETKALNEKMAALKQQMSLLEVKLHNTEAEGEKMKNENLMLKSENDKLKSDSDKTASQVEK 872

Query: 1028 LNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVRE 1087
            L + +  ++     + SD+E K++     L+    +  ++  +  +     E+ +   ++
Sbjct: 873  LEKDLKKSKKDLSQLESDFE-KISAENESLQKKIADKNKLKNETTEKSTLLEQYKNDNKK 931

Query: 1088 QDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEE 1147
            +D+ I +LK+ K   +    + +  +   T+E  S   +                K Q +
Sbjct: 932  KDEIINQLKDKKKKIKQENEQNKNNLQKVTVENTSLQKDLQKSQNDLQKSQNDLQKSQND 991

Query: 1148 EEFIQERSV-LQEQSAKLNTELQECYTKIIQL----ETLNTELTGHDVVNQEQINQLKSK 1202
             + +   +V LQ+   K+ ++LQ+   +  +L    E  NT++ G     +   ++LKS 
Sbjct: 992  LQKLTTENVNLQKDLQKVQSDLQKLQQEREKLQENMENKNTQMKGDFEKIRANYDKLKSD 1051

Query: 1203 LEQLNTENDNLLSTVAELRSSISSA---VDQRGFEIAELWKQHLAQREADFQKTEHELRV 1259
             E+L ++N+ L     E +  +      +     +I  L K   + + ++ Q+ ++EL  
Sbjct: 1052 YEKLKSDNNQLQKEADENKQKLDKKEEKIQNLKLQIQNLQKDQSSMKSSEIQRLQNELE- 1110

Query: 1260 QLSAFESKYEQLLDSVQSSTQEETNKIVTMEQ-VTSLQNKLQDKEEHLRNLQEKYADVIN 1318
            Q+ A     ++ +++     ++   K   ++  +T+LQNK+ + +  L    ++   + N
Sbjct: 1111 QMKANNKSLKENIEAKNKEIEQNKEKNKALKSNLTNLQNKINEIQNALTGKDKENQLLQN 1170

Query: 1319 QIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSI---LNINEENA 1375
            ++     EI+  K                    L ++ +     +E  +    N+  E  
Sbjct: 1171 ELANKNKEIQKLKDDLEKAKSDKNKSQNEITDKLNSKLEKVMAEKEDLLKQNANLQAEMQ 1230

Query: 1376 QLKKSSXXXXXXXXXXXXRVNDAEAKVLELTH-----QLELKDSEIYQKTHEYTITLTQR 1430
            +LK  +             +ND  A+ ++L       Q E+   ++ +K  +   T  + 
Sbjct: 1231 KLKAENEKLKGILKKKTAYINDYYAQTVKLEQKSFGLQKEVDSLDVVKKKFDKLYTSREE 1290

Query: 1431 ND----EFENVRQQLVEYEKRIEDLTYE-KESELAILRLKMHENANHYETMQKESEIERV 1485
             D    E+  +++   ++  + + + Y+ K+ E+  +   + E    YE      E + V
Sbjct: 1291 IDNLFKEYGILQKLYNDHVDKDKLVPYKGKDIEVEKMPALISEVKKKYEDKLNNFEKQTV 1350

Query: 1486 KLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEM-QTALENQEI 1531
              I   NVK+ ++ +  K  AE+  +L+E  A T  +    LEN+++
Sbjct: 1351 LTIYNENVKLIQACNHYKNAAEI--SLQERDATTKLLNDIILENEKL 1395



 Score =  113 bits (271), Expect = 5e-23
 Identities = 192/954 (20%), Positives = 427/954 (44%), Gaps = 122/954 (12%)

Query: 212  EDTKQQMTKMQENFIAMEAEWKDEKQ--RLLKDIESKDVRISSLEEANK-LLEAARFEIS 268
            E+ + +  +  E  + M+ + +++KQ  R   ++    +++ +   ANK L++    E+ 
Sbjct: 456  ENRRDKEREDMETIVQMKNDLENKKQLERDNDELSKTVIKLQNELNANKVLMQKINSELG 515

Query: 269  LEHS-KLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKK 327
             E   K+   L +                 ++++   ++     EK   ++ ++ +  K+
Sbjct: 516  FEKVVKMLNNLTELVSNDDKEELVQLKEENKNLKTKNDKSKAKIEKLKKDLEDLKQEIKE 575

Query: 328  IELLEHLNCQ-IRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSG--------RNT 378
             +     N Q + + NK++ NKL  +  E+  ++S  +    L    S         +N 
Sbjct: 576  SQSKHGENLQNMIENNKDISNKLNQLTAENAKLNSILQNYEKLKQSNSQLQNDYTALQNN 635

Query: 379  ASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXX 438
             +++++  SQL ++  + D + K   ++++K+    +  N+ L+ + + +   D      
Sbjct: 636  NNQLQNNISQLKAKIESADANSKNLSDQLSKM----RDQNEYLIKQNHQL---DNNISVL 688

Query: 439  XXXXXGKDTLIAQL--QLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDV 496
                  KD L   L  QL  Q+            N + +N  + ++ Q KQ    E+KD+
Sbjct: 689  ESKLQEKDNLYKNLSEQLSKQKSQ----------NDDFLNRTSSLENQ-KQNYEKELKDL 737

Query: 497  NVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKL-------KQMQKTIDNFSK 549
              KD +E L    + +   ND++  +  NM   KS+ + KL       K ++  + N S 
Sbjct: 738  --KDKLEDLNKQNKALKNENDKMVTSLHNMETAKSSLEGKLEISDNMVKSLKDQLSNSSS 795

Query: 550  VSDSNKEIVRLTE----ELHHLSQKVAELEEEKGNLQLHLVDYDS-GRMIESDVYKKMIE 604
            +S SNK++  L E    E   L++K+A L+++   L++ L + ++ G  ++++      E
Sbjct: 796  ISQSNKQLQDLYENERKETKALNEKMAALKQQMSLLEVKLHNTEAEGEKMKNENLMLKSE 855

Query: 605  MENLAETRLKAISLLESQKFDLVQ---ELHILQQKYDEV-------EDKLADISQLQSDQ 654
             + L     K  S +E  + DL +   +L  L+  ++++       + K+AD ++L+++ 
Sbjct: 856  NDKLKSDSDKTASQVEKLEKDLKKSKKDLSQLESDFEKISAENESLQKKIADKNKLKNET 915

Query: 655  -----VCSEIKSVHL--EEQIDALSASKKELA------------LVIENLKLDKE--QLY 693
                 +  + K+ +   +E I+ L   KK++             + +EN  L K+  +  
Sbjct: 916  TEKSTLLEQYKNDNKKKDEIINQLKDKKKKIKQENEQNKNNLQKVTVENTSLQKDLQKSQ 975

Query: 694  GTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAE--KISELLAKINHEEQSKIQTQF 751
              ++  +ND +   N LQ    EN++L   L+K+ ++  K+ +   K+    ++K     
Sbjct: 976  NDLQKSQNDLQKSQNDLQKLTTENVNLQKDLQKVQSDLQKLQQEREKLQENMENKNTQMK 1035

Query: 752  GIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQK 811
            G   KI+      + ++S+  K KS   +L++     ++ +  L++K +++ +   + Q 
Sbjct: 1036 GDFEKIRAN---YDKLKSDYEKLKSDNNQLQKEA---DENKQKLDKKEEKIQNLKLQIQN 1089

Query: 812  AYSEYTIQEDELVNRLAVLMDHDRVVEKQLLE-IEHENKELQK---KNQILLEENQNLQI 867
               + +  +   + RL   ++  +   K L E IE +NKE+++   KN+ L     NLQ 
Sbjct: 1090 LQKDQSSMKSSEIQRLQNELEQMKANNKSLKENIEAKNKEIEQNKEKNKALKSNLTNLQN 1149

Query: 868  SLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIED 927
             ++++Q   NAL  K     L ++E      +++ L+ +L++   +       K K   +
Sbjct: 1150 KINEIQ---NALTGKDKENQLLQNELANKNKEIQKLKDDLEKAKSD-------KNKSQNE 1199

Query: 928  LEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLE 987
            +  + N+++E  + +K+ L       ++    L+A++Q+ K   E L      L K    
Sbjct: 1200 ITDKLNSKLEKVMAEKEDL-------LKQNANLQAEMQKLKAENEKLK---GILKKKTAY 1249

Query: 988  LIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSY---MSMVS 1044
            + D + Q  + +   +  Q   E++ L+ ++K+K +++    ++I+N    Y     + +
Sbjct: 1250 INDYYAQTVKLEQKSFGLQ--KEVDSLD-VVKKKFDKLYTSREEIDNLFKEYGILQKLYN 1306

Query: 1045 DY--ESKLAQFTTK---LENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIK 1093
            D+  + KL  +  K   +E M   +  V K+  D K +N E Q ++   ++ +K
Sbjct: 1307 DHVDKDKLVPYKGKDIEVEKMPALISEVKKKYED-KLNNFEKQTVLTIYNENVK 1359



 Score =  109 bits (261), Expect = 8e-22
 Identities = 181/954 (18%), Positives = 404/954 (42%), Gaps = 97/954 (10%)

Query: 619  LESQKFDLV-QELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKE 677
            L + K D + +++  L+   D ++D + + ++         +    LEE+   L+  K +
Sbjct: 293  LSNAKLDTISRQIRELRAVADNIQDDVIEANRKIDQNKIQVLTREQLEEENKRLNLEKSQ 352

Query: 678  LALVIENLKLDKEQLYGTIK-DLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELL 736
            L      L  DK +L   +   L+  K D  ++  N+  + + L  + +++ A K S L 
Sbjct: 353  LDSSNNQLNDDKHRLQSLLNITLQKMKGDNPSEDTNFTDDMLSLQRERDELFA-KNSYLE 411

Query: 737  AKINHEE--QSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYS 794
             ++  E+   +K+     I++     D  I+++      +K  I  ++E+    E+RR  
Sbjct: 412  KQLQREKIHSTKLMAASEIESSTVPADKNIDDL------WKMYIAVVKEN----ENRR-- 459

Query: 795  LERKADQLGSYLQEKQKAYSEYTIQED-ELVNRLAVLMDHDRVVEKQLLEIEHENKELQK 853
             +++ + + + +Q K    ++  ++ D + +++  + + ++    K L++    N EL  
Sbjct: 460  -DKEREDMETIVQMKNDLENKKQLERDNDELSKTVIKLQNELNANKVLMQ--KINSELGF 516

Query: 854  KNQILLEENQNLQISLSDMQQHYNALVEKAN---RTDLAESESTKYQTQLRDLESNLKRI 910
            +  + +  N    +S  D ++      E  N   + D ++++  K +  L DL+  +K  
Sbjct: 517  EKVVKMLNNLTELVSNDDKEELVQLKEENKNLKTKNDKSKAKIEKLKKDLEDLKQEIKES 576

Query: 911  THEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNN 970
              +H   +    +  +D+  + N       +   +L + YEK  +  +QL+      +NN
Sbjct: 577  QSKHGENLQNMIENNKDISNKLNQLTAENAKLNSIL-QNYEKLKQSNSQLQNDYTALQNN 635

Query: 971  IENLNMNVEELNKMNLELID---KHVQKQQTQSPDYTEQYINEINKLN---ALLKQKDEE 1024
               L  N+ +L K  +E  D   K++  Q ++  D  E  I + ++L+   ++L+ K +E
Sbjct: 636  NNQLQNNISQL-KAKIESADANSKNLSDQLSKMRDQNEYLIKQNHQLDNNISVLESKLQE 694

Query: 1025 IIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQIL 1084
               L + ++       S   D+ ++ +    + +N E+E++ +  +L D  + N+ L+  
Sbjct: 695  KDNLYKNLSEQLSKQKSQNDDFLNRTSSLENQKQNYEKELKDLKDKLEDLNKQNKALK-- 752

Query: 1085 VREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKV 1144
              E D  +  L   +        K E  I  + ++ + D  +N                +
Sbjct: 753  -NENDKMVTSLHNMETAKSSLEGKLE--ISDNMVKSLKDQLSN---SSSISQSNKQLQDL 806

Query: 1145 QEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLE 1204
             E E   +E   L E+ A L  ++      +++++  NTE  G  + N+  +  LKS+ +
Sbjct: 807  YENER--KETKALNEKMAALKQQMS-----LLEVKLHNTEAEGEKMKNENLM--LKSEND 857

Query: 1205 QLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAF 1264
            +L +++D   S V +L   +  +            K+ L+Q E+DF+K   E        
Sbjct: 858  KLKSDSDKTASQVEKLEKDLKKS------------KKDLSQLESDFEKISAEN------- 898

Query: 1265 ESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILR 1324
            ES  +++ D       E T K   +EQ    +N  + K+E +  L++K   +  + E  +
Sbjct: 899  ESLQKKIADK-NKLKNETTEKSTLLEQY---KNDNKKKDEIINQLKDKKKKIKQENEQNK 954

Query: 1325 SEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXX 1384
            + ++   V                  DL+ ++Q+  Q  +  +  +  EN  L+K     
Sbjct: 955  NNLQKVTVE----NTSLQKDLQKSQNDLQ-KSQNDLQKSQNDLQKLTTENVNLQKD---- 1005

Query: 1385 XXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEY 1444
                     ++     K+ E    +E K++++     +      +   ++E ++    + 
Sbjct: 1006 LQKVQSDLQKLQQEREKLQE---NMENKNTQMKGDFEKIRANYDKLKSDYEKLKSDNNQL 1062

Query: 1445 EKRIEDLTYE---KESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSL 1501
            +K  ++   +   KE ++  L+L++ +N    ++  K SEI+R++   EL      + SL
Sbjct: 1063 QKEADENKQKLDKKEEKIQNLKLQI-QNLQKDQSSMKSSEIQRLQ--NELEQMKANNKSL 1119

Query: 1502 NKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQ 1555
             + +   NK    E+ +  E   AL++    +  L ++I  +QN +     + Q
Sbjct: 1120 KENIEAKNK----EIEQNKEKNKALKS---NLTNLQNKINEIQNALTGKDKENQ 1166



 Score = 89.4 bits (212), Expect = 7e-16
 Identities = 157/834 (18%), Positives = 361/834 (43%), Gaps = 78/834 (9%)

Query: 789  EDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHEN 848
            + + Y    K D +   ++E  +A ++  IQ+D +     +  +  +V+ ++  ++E EN
Sbjct: 288  QKKEYLSNAKLDTISRQIREL-RAVAD-NIQDDVIEANRKIDQNKIQVLTRE--QLEEEN 343

Query: 849  KELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLK 908
            K L  +   L   N  L      +Q   N  ++K    +   SE T +   +  L+    
Sbjct: 344  KRLNLEKSQLDSSNNQLNDDKHRLQSLLNITLQKMKGDN--PSEDTNFTDDMLSLQRERD 401

Query: 909  RITHEHQTLIVQKKKE-IEDLEIEFNTQIESA-IRDKKVLNEKYEKNIEYVTQLEAQ--- 963
             +  ++  L  Q ++E I   ++   ++IES+ +   K +++ ++  I  V + E +   
Sbjct: 402  ELFAKNSYLEKQLQREKIHSTKLMAASEIESSTVPADKNIDDLWKMYIAVVKENENRRDK 461

Query: 964  -------LQEYKNNIEN---LNMNVEELNK----MNLELIDKHVQKQQTQSPDYTEQYIN 1009
                   + + KN++EN   L  + +EL+K    +  EL    V  Q+  S    E+ + 
Sbjct: 462  EREDMETIVQMKNDLENKKQLERDNDELSKTVIKLQNELNANKVLMQKINSELGFEKVVK 521

Query: 1010 EINKLNALLKQKD-EEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVS 1068
             +N L  L+   D EE++ L ++  N +        + +SK      K+E ++++++ + 
Sbjct: 522  MLNNLTELVSNDDKEELVQLKEENKNLKTK------NDKSK-----AKIEKLKKDLEDLK 570

Query: 1069 KQLLDSK-QHNEELQILVREQDDQIKELKE-TKLTFEMNIPKTEGMIISSTIEPMSDDAN 1126
            +++ +S+ +H E LQ ++    D   +L + T    ++N        +  +   + +D  
Sbjct: 571  QEIKESQSKHGENLQNMIENNKDISNKLNQLTAENAKLNSILQNYEKLKQSNSQLQNDYT 630

Query: 1127 NVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELT 1186
             +             LK + E      ++ L +Q +K+  + +     I Q   L+  ++
Sbjct: 631  ALQNNNNQLQNNISQLKAKIESADANSKN-LSDQLSKMRDQNEYL---IKQNHQLDNNIS 686

Query: 1187 GHDVVNQEQINQLKSKLEQLN---TENDNLLSTVAEL---RSSISSAVDQRGFEIAELWK 1240
              +   QE+ N  K+  EQL+   ++ND+ L+  + L   + +    +     ++ +L K
Sbjct: 687  VLESKLQEKDNLYKNLSEQLSKQKSQNDDFLNRTSSLENQKQNYEKELKDLKDKLEDLNK 746

Query: 1241 QHLA-QREADFQKTE-HELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNK 1298
            Q+ A + E D   T  H +    S+ E K E   + V+S   + +N     +    LQ+ 
Sbjct: 747  QNKALKNENDKMVTSLHNMETAKSSLEGKLEISDNMVKSLKDQLSNSSSISQSNKQLQDL 806

Query: 1299 LQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQS 1358
             +++ +  + L EK A +  Q+ +L  ++ + +                    L++EN  
Sbjct: 807  YENERKETKALNEKMAALKQQMSLLEVKLHNTEAEGEKMKNENLM--------LKSENDK 858

Query: 1359 YKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQ 1418
             K   +++   + +    LKKS                + E+   ++  + +LK+    +
Sbjct: 859  LKSDSDKTASQVEKLEKDLKKSKKDLSQLESDFEKISAENESLQKKIADKNKLKN----E 914

Query: 1419 KTHEYTITLTQRND--EFENVRQQLVEYEKRIEDLTYEKESEL---AILRLKMHENANHY 1473
             T + T+    +ND  + + +  QL + +K+I+    + ++ L    +    + ++    
Sbjct: 915  TTEKSTLLEQYKNDNKKKDEIINQLKDKKKKIKQENEQNKNNLQKVTVENTSLQKDLQKS 974

Query: 1474 ETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQ---- 1529
            +   ++S+ +  K   +L    TE+V+L K + ++   L++   +  ++Q  +EN+    
Sbjct: 975  QNDLQKSQNDLQKSQNDLQKLTTENVNLQKDLQKVQSDLQKLQQEREKLQENMENKNTQM 1034

Query: 1530 --EIEIVTLN-DEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKEL 1580
              + E +  N D++ +    +++ ++++QK    A + KQ  D++ +   N +L
Sbjct: 1035 KGDFEKIRANYDKLKSDYEKLKSDNNQLQKE---ADENKQKLDKKEEKIQNLKL 1085


>UniRef50_A0BRG1 Cluster: Chromosome undetermined scaffold_122, whole
            genome shotgun sequence; n=2; Paramecium tetraurelia|Rep:
            Chromosome undetermined scaffold_122, whole genome
            shotgun sequence - Paramecium tetraurelia
          Length = 1949

 Score =  150 bits (363), Expect = 4e-34
 Identities = 245/1159 (21%), Positives = 531/1159 (45%), Gaps = 104/1159 (8%)

Query: 491  DEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKT-IDNFSK 549
            + +  VN K L++++ ++  +I +L  E++   KNM ++  +  +    + KT I+   +
Sbjct: 393  ERLLQVNQK-LMQEIATSTNKIKELQLELEMM-KNMSRISMSMSMIEDPVMKTKIEQLEQ 450

Query: 550  VSDS-NKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENL 608
             +    K+I  L EEL    Q   + ++   +LQ+  +   + R +E ++ K   E+  L
Sbjct: 451  ENQYLQKKISILEEELSKKKQPKPQKQQPDRDLQIQKLTEANKRYLEENL-KLFEEIRQL 509

Query: 609  AETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQI 668
             E    +  L  S K   +QE +++  + ++  +++  I  L+  ++  +I+ +  + Q 
Sbjct: 510  REKFDYSSVLQNSMKDSQIQE-NVVNHQLEQQIERMQQIHNLEIQKMKKKIEKLTNDLQ- 567

Query: 669  DALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMS 728
            DA    K+   L+ +N +L +E ++ T + ++N  +  ++K  +    N  + +  +   
Sbjct: 568  DANQVKKQFEQLIKQNKRLVEENMHLT-EQIKNLADINLSKSFSDNMFNSKIFNSDQYKE 626

Query: 729  AEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVM 788
             E+   +L + N E QSK+  Q   D + Q++   I+ +E E++KYK++I  +E + +V 
Sbjct: 627  LEQQLVVLKRKNEEIQSKLDIQLQRDTQQQDK---IKQLEQEIAKYKNQIREIEYNNSVS 683

Query: 789  EDRRYSLERKADQL----GSYLQEKQKAYSEYT--IQEDELVN-RLAVLMDHDRVVEKQL 841
             + +  L+ + D       + ++E  +   +Y   +Q+ E +N ++  L +    ++++ 
Sbjct: 684  NEVKL-LQNQIDDYQKAKDNLMRENIQLRDDYATLLQDKEYLNGKIKQLENSIFELKQKQ 742

Query: 842  LEIEHENKELQK-----------KNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAE 890
            ++++ EN+ L+            + Q L  +N+NL   +  +Q   NA  +  N+++L+ 
Sbjct: 743  MQLQEENRTLKLFPQSAERQFSVQIQQLQLQNKNLTEEIVRLQSQQNAFKD-LNQSNLSI 801

Query: 891  SESTK----YQTQLRDLESNLKRITH-EHQTLIVQKKKEIEDLE--IEFNTQIESAIRDK 943
            SES      Y  +   L  N K +   E+Q L ++ + E +  E  I+F  QI++   ++
Sbjct: 802  SESVLGSKIYDAKEYKLLENQKELLFTENQQLKLEIRSEYQKSEDQIKFQEQIKALQNER 861

Query: 944  KVLNEKYEKNIEY----VTQLEAQLQEYKNNIENLNMNVEELNKM-NLELIDKHVQKQQT 998
             +LN++   N E     +  L+ Q+ +    ++N++++      + N   +D + QKQQ 
Sbjct: 862  DILNQQLISNKEQHSRQIITLQNQIDKLNQQLQNVSLSESRYRVIINDNKVDDYAQKQQD 921

Query: 999  --QSPDYTEQYINEINKL----NALLKQKDEEIIALNQKIN--NAQVSYMSMVSDYESKL 1050
              +  +  +Q   +I KL    +  ++++  ++  L  + N  + +V+Y    S  ES +
Sbjct: 922  ILRLENENKQLNVQIQKLQLQYDTEIRRQQTQLSDLQFENNKLSREVTYSKQYS--ESVV 979

Query: 1051 AQFTTKLE--NMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKE--TKLTFE-MN 1105
               T K +  + E E+ ++  QL D K H  +L+++     + ++EL++  +KL  E  N
Sbjct: 980  FNQTEKKQYSSQESEIVQLKNQLAD-KTH--QLKVIQTNSQNSMEELQQVISKLGLENKN 1036

Query: 1106 IPKTEGMI-------ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQ 1158
            + +    I       ++  +E + +   N++             K QE++ FI+   V  
Sbjct: 1037 MNEVHNSIKSRLEAQVNKLVEQLREKDQNINKIQDELRRKEQIAKQQEDDLFIKSNQV-- 1094

Query: 1159 EQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVA 1218
            EQ  + N  L       +QL  LN EL    + +    +  KS ++    EN  L S + 
Sbjct: 1095 EQLIQQNKGLA------LQLNNLNFELQELRMASLSH-SFSKSHIDVRENENQELQSEIQ 1147

Query: 1219 ELRSSISSAVDQ--RGFEIAELWKQHLA----QREADFQKTEHELRVQLSAF-ESKYEQL 1271
             LR+ I +   Q  +  + ++L K        QRE    K + ++ ++ S F + ++ Q 
Sbjct: 1148 ILRNQIQTLESQSTKQLDNSKLIKLEDEIVHYQREISLIKNKLQITLEDSEFYKREFTQS 1207

Query: 1272 LDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEK 1331
               ++   +E + K    E++++ +N+L   +   + L ++ +D    I+  + +I DE 
Sbjct: 1208 QQQIEKMRKELSQK--QSEKLSTQENELVQIKRTNQQLIQENSDQSITIQNQQQQI-DEL 1264

Query: 1332 VAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXX 1391
                                L+ E +  ++  +Q I+ I E ++Q +             
Sbjct: 1265 QQDLNEYIESNQTITKLKMQLQLEGEKLQRENQQLIIKIQELSSQKQMGRDQELNELIRK 1324

Query: 1392 XXRVNDAEAK-VLELTHQLELKDSEIYQKTHEYTITLTQ-RNDEFENVRQQLVEYEKRIE 1449
               +   +AK ++    Q +L D+       + T+ ++Q + DEFE       +Y++ ++
Sbjct: 1325 LQSMEQDKAKLIISCEQQQQLIDNL------KSTLEISQNKKDEFEIKLHSTEQYKQELQ 1378

Query: 1450 DLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKI-TESVSLNKQVAEL 1508
                E++ ++  L+ + +  +   +T Q++   ++ K + EL V+I  +   L +Q+ +L
Sbjct: 1379 ISLKEQDQKIKQLQQESYYLSKELDTEQQKHTTQKKK-VNELTVQIQNKDNELQQQINKL 1437

Query: 1509 NKALEEEVAKTNEMQTALENQEIEIVTLNDEITN------LQNMVRASSSKIQKHVSFAS 1562
             K LEE++ K ++  + L NQ  ++   N++ TN       Q + + +  K Q H S   
Sbjct: 1438 -KNLEEQILKKDQQISTLNNQISQLKQENNKYTNEIIPKLNQQIDQETLEKNQLHKSLQE 1496

Query: 1563 DTKQGRDEQLDNTMNKELL 1581
               Q   + L  T  K  L
Sbjct: 1497 QFVQMEQQILSMTREKSPL 1515



 Score =  142 bits (345), Expect = 5e-32
 Identities = 239/1153 (20%), Positives = 509/1153 (44%), Gaps = 120/1153 (10%)

Query: 480  KVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVK-SNHKLKLK 538
            K QEQ+K   N+  +D+  + LI   +    QI  L ++ID  N+ +  V  S  + ++ 
Sbjct: 849  KFQEQIKALQNE--RDILNQQLISNKEQHSRQIITLQNQIDKLNQQLQNVSLSESRYRVI 906

Query: 539  QMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAEL------EEEKGNLQLHLVDYDSGR 592
                 +D++++     ++I+RL  E   L+ ++ +L      E  +   QL  + +++ +
Sbjct: 907  INDNKVDDYAQ---KQQDILRLENENKQLNVQIQKLQLQYDTEIRRQQTQLSDLQFENNK 963

Query: 593  MIESDVYKKMI-EMENLAETRLKAISLLESQ----KFDLVQELHILQQKYDEVEDKLADI 647
            +     Y K   E     +T  K  S  ES+    K  L  + H L+      ++ + ++
Sbjct: 964  LSREVTYSKQYSESVVFNQTEKKQYSSQESEIVQLKNQLADKTHQLKVIQTNSQNSMEEL 1023

Query: 648  SQLQS---------DQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKD 698
             Q+ S         ++V + IKS  LE Q++ L    +E    I  ++ +  +     K 
Sbjct: 1024 QQVISKLGLENKNMNEVHNSIKS-RLEAQVNKLVEQLREKDQNINKIQDELRRKEQIAKQ 1082

Query: 699  LENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHE-EQSKIQTQFG----I 753
             E+D     N+++  IQ+N  L  +L  ++ E     +A ++H   +S I  +      +
Sbjct: 1083 QEDDLFIKSNQVEQLIQQNKGLALQLNNLNFELQELRMASLSHSFSKSHIDVRENENQEL 1142

Query: 754  DAKIQERDLYIENIESELSKY--KSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQK 811
             ++IQ     I+ +ES+ +K    S++ +LE+ I V   R  SL +   Q+   L++ + 
Sbjct: 1143 QSEIQILRNQIQTLESQSTKQLDNSKLIKLEDEI-VHYQREISLIKNKLQIT--LEDSEF 1199

Query: 812  AYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSD 871
               E+T Q  + + ++   +   +   ++L   E+E  ++++ NQ L++EN +  I++ +
Sbjct: 1200 YKREFT-QSQQQIEKMRKELSQKQ--SEKLSTQENELVQIKRTNQQLIQENSDQSITIQN 1256

Query: 872  MQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIE 931
             QQ  + L +  N    +    TK + QL+ LE   +++  E+Q LI++ ++     ++ 
Sbjct: 1257 QQQQIDELQQDLNEYIESNQTITKLKMQLQ-LEG--EKLQRENQQLIIKIQELSSQKQMG 1313

Query: 932  FNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDK 991
             + ++   IR  + + +   K I    Q +  +   K+ +E ++ N ++  ++ L   ++
Sbjct: 1314 RDQELNELIRKLQSMEQDKAKLIISCEQQQQLIDNLKSTLE-ISQNKKDEFEIKLHSTEQ 1372

Query: 992  HVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLA 1051
            + Q+ Q    +  ++           +KQ  +E   L+++++  Q  + +     + K+ 
Sbjct: 1373 YKQELQISLKEQDQK-----------IKQLQQESYYLSKELDTEQQKHTTQ----KKKVN 1417

Query: 1052 QFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKE--TKLTFEMNIPKT 1109
            + T +++N + E+Q+   +L + ++   +    +   ++QI +LK+   K T E+ IPK 
Sbjct: 1418 ELTVQIQNKDNELQQQINKLKNLEEQILKKDQQISTLNNQISQLKQENNKYTNEI-IPKL 1476

Query: 1110 EGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQ 1169
               I   T+E      N +               VQ E++ +   S+ +E+S   +    
Sbjct: 1477 NQQIDQETLEK-----NQLHKSLQEQF-------VQMEQQIL---SMTREKSPLKSKSNS 1521

Query: 1170 ECYTKIIQLETLNTELTGHD-VVNQEQ--INQLKSKLEQLNTENDNLLSTVAELRSSISS 1226
            +C  K    ++LN ++T  + ++NQ+   I Q   KL+ L  +N+ LL  + +L   +  
Sbjct: 1522 QC--KPFD-QSLNEKITQQEQIINQKNQIIEQQLEKLKILTQQNNGLLHQINKLNDDLRD 1578

Query: 1227 AVDQ-----RGFEIAELWKQHLAQREADFQKT-EHELRVQLSAFES------KYEQLLDS 1274
              D+     R  E   + K   ++  AD     +H+ + Q   +ES      +Y+Q   +
Sbjct: 1579 LQDKSFSLDRSSETYLINKSFNSKYNADNDLILQHQYQSQ-DIYESDRKRQSQYQQFEQT 1637

Query: 1275 VQSSTQEETNKIVTMEQVTS-LQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVA 1333
            +Q S QE  +  + ++Q+   +Q +  D E+ ++N+    +  I ++     ++  E+  
Sbjct: 1638 LQESVQENKSLKLEIDQLKQFIQQQKNDYEKQIQNMSTSNSLQIQELNTKLEKLSQEEKK 1697

Query: 1334 FXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEEN-------AQLKKSSXXXXX 1386
                             D   E    KQ  EQS   +N E         +L++       
Sbjct: 1698 HQNMPSQNLRNEYQQQIDRLEEELLRKQGVEQSNQRLNNEIKIQITKVVELQQQLEGLRQ 1757

Query: 1387 XXXXXXXRVNDAEAKVLELTH-QLELKDSEIYQKTHEYTITLTQRNDEF-------ENVR 1438
                   ++ + E  +  L   +++  DS   QK  E      Q  +E        +  +
Sbjct: 1758 QNQQLSNQIKEQEELIRSLQKMKIQNSDSSEAQKEGELNQLTQQLQNETLILKGQNQKYQ 1817

Query: 1439 QQLVEYEKRIEDLTYEKESELAILRLKMHE-NANHYETMQKESEIERVKLIEELNVKITE 1497
            QQ+ EY+ +IE L  E + +   + LK  + N N+ +T + E   E+++L+++       
Sbjct: 1818 QQISEYQSKIETLENEIQKKSQQISLKDSQVNQNNRKTKKLE---EQIQLLQDQLKGQGG 1874

Query: 1498 SVSLNKQ--VAELNKALEEEVAKTNEMQTALE--NQEIEIVTLNDEITNLQNMVRASSSK 1553
             V+ NK   + +L   LE++  +  E Q  ++  +++I+ +T ++     +N       K
Sbjct: 1875 LVTQNKDEVIVQLQNELEQKRTEMFEFQKQIKQLDEQIDRLTKSNSALMEENCRLNDQLK 1934

Query: 1554 IQKHVSFASDTKQ 1566
               +VS+ S+  Q
Sbjct: 1935 DNLNVSYLSNDSQ 1947



 Score =  128 bits (308), Expect = 2e-27
 Identities = 237/1226 (19%), Positives = 547/1226 (44%), Gaps = 120/1226 (9%)

Query: 152  KEKDNALSVLQVKMKIMETTILDLQEKINEK-----DQIIEAKNKATTXXXXXXXXXXXX 206
            K KDN +    ++++    T+L  +E +N K     + I E K K               
Sbjct: 698  KAKDNLMRE-NIQLRDDYATLLQDKEYLNGKIKQLENSIFELKQKQMQLQEENRTLKLFP 756

Query: 207  XXXXXEDTKQ-QMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARF 265
                 + + Q Q  ++Q   +  E      +Q   KD+   ++ IS     +K+ +A  +
Sbjct: 757  QSAERQFSVQIQQLQLQNKNLTEEIVRLQSQQNAFKDLNQSNLSISESVLGSKIYDAKEY 816

Query: 266  EISLEHSK--LAQELEQXXXXXXXXXXXXXXLAK--QSIEPSCEEKTEIEEKGSLEIANM 321
            ++ LE+ K  L  E +Q                K  + I+    E+  + ++    I+N 
Sbjct: 817  KL-LENQKELLFTENQQLKLEIRSEYQKSEDQIKFQEQIKALQNERDILNQQ---LISNK 872

Query: 322  TELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASK 381
             + +++I  L++   QI + N++L+N ++   +  + + + +K       ++      ++
Sbjct: 873  EQHSRQIITLQN---QIDKLNQQLQN-VSLSESRYRVIINDNKVDDYAQKQQDILRLENE 928

Query: 382  MKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLV-DKEYVISEKDTXXXXXXX 440
             K    Q+    L  DT+ +  + +++ L+     L++++   K+Y  SE          
Sbjct: 929  NKQLNVQIQKLQLQYDTEIRRQQTQLSDLQFENNKLSREVTYSKQY--SESVVFNQTEKK 986

Query: 441  XXXGKDTLIAQL--QLEHQQHMEGPSLIHVGTNTEDVNEIAK---VQEQLKQELNDEIK- 494
                +++ I QL  QL  + H       +   + E++ ++     ++ +   E+++ IK 
Sbjct: 987  QYSSQESEIVQLKNQLADKTHQLKVIQTNSQNSMEELQQVISKLGLENKNMNEVHNSIKS 1046

Query: 495  --DVNVKDLIEKLKSAEEQITQLNDE------IDAANKNMIKVKSNHKLKLKQMQKTIDN 546
              +  V  L+E+L+  ++ I ++ DE      I    ++ + +KSN   +L Q  K +  
Sbjct: 1047 RLEAQVNKLVEQLREKDQNINKIQDELRRKEQIAKQQEDDLFIKSNQVEQLIQQNKGLA- 1105

Query: 547  FSKVSDSNKEI--VRLTEELHHLSQKVAELEE-EKGNLQLHL-VDYDSGRMIESDVYK-- 600
              ++++ N E+  +R+    H  S+   ++ E E   LQ  + +  +  + +ES   K  
Sbjct: 1106 -LQLNNLNFELQELRMASLSHSFSKSHIDVRENENQELQSEIQILRNQIQTLESQSTKQL 1164

Query: 601  ---KMIEMENLAETRLKAISLLESQKFDLVQELHILQQKY----DEVEDKLADISQLQSD 653
               K+I++E+      + ISL++++    +++    ++++     ++E    ++SQ QS+
Sbjct: 1165 DNSKLIKLEDEIVHYQREISLIKNKLQITLEDSEFYKREFTQSQQQIEKMRKELSQKQSE 1224

Query: 654  QVCS-EIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKD-LENDKEDIMNKLQ 711
            ++ + E + V ++     L     + ++ I+N +   ++L   + + +E+++     K+Q
Sbjct: 1225 KLSTQENELVQIKRTNQQLIQENSDQSITIQNQQQQIDELQQDLNEYIESNQTITKLKMQ 1284

Query: 712  NYIQ------ENMDLTDKLEKMSAEK-------ISELLAKINHEEQSKIQTQFGIDAKIQ 758
              ++      EN  L  K++++S++K       ++EL+ K+   EQ K +     + + Q
Sbjct: 1285 LQLEGEKLQRENQQLIIKIQELSSQKQMGRDQELNELIRKLQSMEQDKAKLIISCEQQQQ 1344

Query: 759  ERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSL---ERKADQLGS---YLQEKQKA 812
              D     +E   +K      +L  +    ++ + SL   ++K  QL     YL ++   
Sbjct: 1345 LIDNLKSTLEISQNKKDEFEIKLHSTEQYKQELQISLKEQDQKIKQLQQESYYLSKELDT 1404

Query: 813  YSEYTIQEDELVNRLAV-LMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSD 871
              +    + + VN L V + + D  +++Q+ ++++  +++ KK+Q +   N  +     +
Sbjct: 1405 EQQKHTTQKKKVNELTVQIQNKDNELQQQINKLKNLEEQILKKDQQISTLNNQISQLKQE 1464

Query: 872  MQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIE 931
              ++ N ++ K N+    + E+ +     + L+    ++  E Q L + ++K    L+ +
Sbjct: 1465 NNKYTNEIIPKLNQQ--IDQETLEKNQLHKSLQEQFVQM--EQQILSMTREKS--PLKSK 1518

Query: 932  FNTQIESAIRDKKVLNEKYEKNIEYVTQ----LEAQLQEYKNNIENLNMNVEELNKMNLE 987
             N+Q +   +    LNEK  +  + + Q    +E QL++ K   +  N  + ++NK+N +
Sbjct: 1519 SNSQCKPFDQS---LNEKITQQEQIINQKNQIIEQQLEKLKILTQQNNGLLHQINKLNDD 1575

Query: 988  LIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYE 1047
            L D  +Q +       +E Y+  INK        D ++I  +Q    +Q  Y S     +
Sbjct: 1576 LRD--LQDKSFSLDRSSETYL--INKSFNSKYNADNDLILQHQY--QSQDIYESD-RKRQ 1628

Query: 1048 SKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIP 1107
            S+  QF   L+   +E + +  ++   KQ       + ++++D  K+++    +  + I 
Sbjct: 1629 SQYQQFEQTLQESVQENKSLKLEIDQLKQ------FIQQQKNDYEKQIQNMSTSNSLQIQ 1682

Query: 1108 KTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTE 1167
            +     +++ +E +S +                  ++   EE +  +  +++ + +LN E
Sbjct: 1683 E-----LNTKLEKLSQEEKKHQNMPSQNLRNEYQQQIDRLEEELLRKQGVEQSNQRLNNE 1737

Query: 1168 LQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSA 1227
            ++   TK+++L+    +L G    NQ+  NQ+K + E + +          ++++S SS 
Sbjct: 1738 IKIQITKVVELQQ---QLEGLRQQNQQLSNQIKEQEELIRSLQK------MKIQNSDSSE 1788

Query: 1228 VDQRGFEIAELWKQHLAQREADFQKTEHE-LRVQLSAFESKYEQLLDSVQSSTQEETNKI 1286
              + G E+ +L +Q   Q E    K +++  + Q+S ++SK E L + +Q  +Q+ + K 
Sbjct: 1789 AQKEG-ELNQLTQQ--LQNETLILKGQNQKYQQQISEYQSKIETLENEIQKKSQQISLK- 1844

Query: 1287 VTMEQVTSLQNKLQDKEEHLRNLQEK 1312
                QV     K +  EE ++ LQ++
Sbjct: 1845 --DSQVNQNNRKTKKLEEQIQLLQDQ 1868



 Score =  122 bits (293), Expect = 1e-25
 Identities = 234/1142 (20%), Positives = 511/1142 (44%), Gaps = 123/1142 (10%)

Query: 485  LKQELNDEIKDVNVKDLIEKLK-SAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKT 543
            + Q+      D N    +E L+ S  +Q  Q +D+   +N+N ++V+ N+++   + +  
Sbjct: 111  ISQQYEINCNDQNWIFSLEYLENSTTQQKIQYSDQCILSNQNQLQVQFNNQIMKFKCKDD 170

Query: 544  IDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMI 603
             D F     S + + R+   L  ++  + +L +++ N Q  L    + ++++    K ++
Sbjct: 171  KDAFCAFFISMQSLRRV--HLKFIAYNIGKLNQKQVNFQSLL----NAQLLQLINEKSVM 224

Query: 604  EMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVH 663
             ++   E     + +  SQ F    ++ I Q K +        ++QLQS++         
Sbjct: 225  PIKKF-EPIQNNVMMATSQDFRTNNQIQITQLKQE--------VAQLQSEKQ-------K 268

Query: 664  LEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDK 723
            L++QID L    KEL +  ++    ++QL      ++   + + N++ +  Q   DL ++
Sbjct: 269  LQQQIDKLFKENKELEINSKSNTASRDQL----DSMDRLIQSLKNEVYSLKQRETDLMNQ 324

Query: 724  LEKMSAEKISELLAKINHEEQSKIQTQFGIDAKI-QERDLYIE------NIESELSKYK- 775
              +++       LA     ++S  Q+QF  + K+ Q +D+ +E       ++ EL+KY+ 
Sbjct: 325  NGRLT-------LALNEKNDKSLSQSQFLDEMKVKQYQDMLLECNNEKVRLQEELNKYQK 377

Query: 776  -SRICRLEESIAVMEDRRYSLERK-ADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDH 833
                 R  ++I   ++R   + +K   ++ +   + ++   E  + ++     +++ M  
Sbjct: 378  FGSSSRTSQNIDGEKERLLQVNQKLMQEIATSTNKIKELQLELEMMKNMSRISMSMSMIE 437

Query: 834  DRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESES 893
            D V++ ++ ++E EN+ LQKK  IL EE       LS  +Q      ++ +R DL   + 
Sbjct: 438  DPVMKTKIEQLEQENQYLQKKISILEEE-------LSKKKQP-KPQKQQPDR-DLQIQKL 488

Query: 894  TKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKN 953
            T  +   R LE NLK         I Q +++ +   +  N+  +S I++  V+N + E+ 
Sbjct: 489  T--EANKRYLEENLKLFEE-----IRQLREKFDYSSVLQNSMKDSQIQE-NVVNHQLEQQ 540

Query: 954  IEYVTQL-EAQLQEYKNNIENLNMNVEELN--KMNLELIDKHVQKQQTQSPDYTEQYINE 1010
            IE + Q+   ++Q+ K  IE L  ++++ N  K   E + K  ++   ++   TEQ I  
Sbjct: 541  IERMQQIHNLEIQKMKKKIEKLTNDLQDANQVKKQFEQLIKQNKRLVEENMHLTEQ-IKN 599

Query: 1011 INKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQ 1070
            +  +N L K   + +   N KI N         SD   +L Q    L+   EE+Q  SK 
Sbjct: 600  LADIN-LSKSFSDNM--FNSKIFN---------SDQYKELEQQLVVLKRKNEEIQ--SK- 644

Query: 1071 LLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTE-GMIISSTIEPMSDDANNVD 1129
             LD +   +       +Q D+IK+L++    ++  I + E    +S+ ++ + +  ++  
Sbjct: 645  -LDIQLQRD------TQQQDKIKQLEQEIAKYKNQIREIEYNNSVSNEVKLLQNQIDDYQ 697

Query: 1130 XXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHD 1189
                        L+  +    +Q++  L  +  +L   + E   K +QL+  N  L    
Sbjct: 698  KAKDNLMRENIQLR-DDYATLLQDKEYLNGKIKQLENSIFELKQKQMQLQEENRTL---K 753

Query: 1190 VVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREAD 1249
            +  Q    Q   +++QL  +N NL   +  L+S  ++  D     ++ + +  L  +  D
Sbjct: 754  LFPQSAERQFSVQIQQLQLQNKNLTEEIVRLQSQQNAFKDLNQSNLS-ISESVLGSKIYD 812

Query: 1250 FQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNL 1309
              K    L  Q     ++ +QL   ++S  Q+  ++I   EQ+ +LQN+     + L + 
Sbjct: 813  -AKEYKLLENQKELLFTENQQLKLEIRSEYQKSEDQIKFQEQIKALQNERDILNQQLISN 871

Query: 1310 QEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILN 1369
            +E+++    QI  L+++I D+                    D + ++ + KQ     + N
Sbjct: 872  KEQHS---RQIITLQNQI-DKLNQQLQNVSLSESRYRVIINDNKVDDYAQKQQDILRLEN 927

Query: 1370 INEE-NAQLKKSSXXXXXXXXXXXXRVNDAEAK----VLELTHQLELKDSEIYQKTH--E 1422
             N++ N Q++K              +++D + +      E+T+  +  +S ++ +T   +
Sbjct: 928  ENKQLNVQIQKLQLQYDTEIRRQQTQLSDLQFENNKLSREVTYSKQYSESVVFNQTEKKQ 987

Query: 1423 YT---ITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANH-YETMQK 1478
            Y+     + Q  ++  +   QL   +   ++   E +  ++ L L+ ++N N  + +++ 
Sbjct: 988  YSSQESEIVQLKNQLADKTHQLKVIQTNSQNSMEELQQVISKLGLE-NKNMNEVHNSIKS 1046

Query: 1479 ESEIERVKLIEEL-----NV-KITESVSLNKQVAELNKALEEEVAKTNEMQTALENQE-- 1530
              E +  KL+E+L     N+ KI + +   +Q+A+  +  ++   K+N+++  ++  +  
Sbjct: 1047 RLEAQVNKLVEQLREKDQNINKIQDELRRKEQIAKQQE--DDLFIKSNQVEQLIQQNKGL 1104

Query: 1531 -IEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNK-ELLDAVPRAE 1588
             +++  LN E+  L+ M   S S  + H+    +  Q    ++    N+ + L++    +
Sbjct: 1105 ALQLNNLNFELQELR-MASLSHSFSKSHIDVRENENQELQSEIQILRNQIQTLESQSTKQ 1163

Query: 1589 LD 1590
            LD
Sbjct: 1164 LD 1165



 Score =  119 bits (286), Expect = 8e-25
 Identities = 246/1267 (19%), Positives = 526/1267 (41%), Gaps = 97/1267 (7%)

Query: 298  QSIEPSCEEKTEIEEKGSLEIANMTELTKKIEL-LEHLNCQIRQTNKELENKLATMGTES 356
            Q+I+   E   ++ +K   EIA  T   K+++L LE +    R +      +   M T+ 
Sbjct: 386  QNIDGEKERLLQVNQKLMQEIATSTNKIKELQLELEMMKNMSRISMSMSMIEDPVMKTKI 445

Query: 357  KAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQS 416
            + +   ++     IS      +  K   P  Q        D D +I K   A    + ++
Sbjct: 446  EQLEQENQYLQKKISILEEELSKKKQPKPQKQ------QPDRDLQIQKLTEANKRYLEEN 499

Query: 417  LNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQ--QHMEGPSLIHVGTNTED 474
            L   L ++   + EK             KD+ I +  + HQ  Q +E    IH   N E 
Sbjct: 500  LK--LFEEIRQLREKFDYSSVLQNSM--KDSQIQENVVNHQLEQQIERMQQIH---NLE- 551

Query: 475  VNEIAKVQEQLKQELNDEIKDVN-VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNH 533
               I K+++++ ++L ++++D N VK   E+L    +++ + N  +    KN+  +  + 
Sbjct: 552  ---IQKMKKKI-EKLTNDLQDANQVKKQFEQLIKQNKRLVEENMHLTEQIKNLADINLSK 607

Query: 534  KLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKG-NLQLHLVDYDSGR 592
                      I N    SD  KE   L ++L  L +K  E++ +    LQ      D  +
Sbjct: 608  SFSDNMFNSKIFN----SDQYKE---LEQQLVVLKRKNEEIQSKLDIQLQRDTQQQDKIK 660

Query: 593  MIESDV--YKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQL 650
             +E ++  YK  I       +    + LL++Q  D  +    L ++  ++ D  A + Q 
Sbjct: 661  QLEQEIAKYKNQIREIEYNNSVSNEVKLLQNQIDDYQKAKDNLMRENIQLRDDYATLLQ- 719

Query: 651  QSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKL----DKEQLYGTIKDLENDKEDI 706
              + +  +IK   LE  I  L   + +L      LKL     + Q    I+ L+   +++
Sbjct: 720  DKEYLNGKIK--QLENSIFELKQKQMQLQEENRTLKLFPQSAERQFSVQIQQLQLQNKNL 777

Query: 707  MNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIEN 766
              ++     +     D  +   +   S L +KI   ++ K+        + Q+  L+ EN
Sbjct: 778  TEEIVRLQSQQNAFKDLNQSNLSISESVLGSKIYDAKEYKL-------LENQKELLFTEN 830

Query: 767  IESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNR 826
             + +L + +S   + E+ I   E  + +L+ + D L   L   ++ +S   I     +++
Sbjct: 831  QQLKL-EIRSEYQKSEDQIKFQEQIK-ALQNERDILNQQLISNKEQHSRQIITLQNQIDK 888

Query: 827  LAVLMDHDRVVEKQLLEIEHENK---ELQKKNQILLEENQN--LQISLSDMQQHYNALVE 881
            L   + +  + E +   I ++NK     QK+  IL  EN+N  L + +  +Q  Y+  + 
Sbjct: 889  LNQQLQNVSLSESRYRVIINDNKVDDYAQKQQDILRLENENKQLNVQIQKLQLQYDTEIR 948

Query: 882  KANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIR 941
            +  +T L++    +++      E    +   E       +KK+    E E   Q+++ + 
Sbjct: 949  R-QQTQLSD---LQFENNKLSREVTYSKQYSESVVFNQTEKKQYSSQESEI-VQLKNQLA 1003

Query: 942  DK----KVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMN-VEELNKMNLELIDKHVQKQ 996
            DK    KV+    + ++E + Q+ ++L      +EN NMN V    K  LE     + +Q
Sbjct: 1004 DKTHQLKVIQTNSQNSMEELQQVISKL-----GLENKNMNEVHNSIKSRLEAQVNKLVEQ 1058

Query: 997  QTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTK 1056
              +      +  +E+ +   + KQ+++++   + ++   Q+   +     +     F  +
Sbjct: 1059 LREKDQNINKIQDELRRKEQIAKQQEDDLFIKSNQVE--QLIQQNKGLALQLNNLNFELQ 1116

Query: 1057 LENMEEEMQRVSKQLLDSKQH-NEELQILVREQDDQIK--ELKETKLTFEMNIPKTEGMI 1113
               M       SK  +D +++ N+ELQ  ++   +QI+  E + TK      + K E  I
Sbjct: 1117 ELRMASLSHSFSKSHIDVRENENQELQSEIQILRNQIQTLESQSTKQLDNSKLIKLEDEI 1176

Query: 1114 ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYT 1173
            +    E +S   N +                 +++     + + Q+QS KL+T+  E   
Sbjct: 1177 VHYQRE-ISLIKNKLQITLEDSEFYKREFTQSQQQIEKMRKELSQKQSEKLSTQENE--- 1232

Query: 1174 KIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGF 1233
             ++Q++  N +L      N +Q   ++++ +Q++ E    L+   E   +I+    Q   
Sbjct: 1233 -LVQIKRTNQQLIQE---NSDQSITIQNQQQQID-ELQQDLNEYIESNQTITKLKMQLQL 1287

Query: 1234 EIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVT 1293
            E  +L +++   ++   +  E   + Q+   + +  +L+  +QS  Q++   I++ EQ  
Sbjct: 1288 EGEKLQREN---QQLIIKIQELSSQKQMGR-DQELNELIRKLQSMEQDKAKLIISCEQQQ 1343

Query: 1294 SLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLR 1353
             L + L+   E  +N ++++   ++  E  + E++                      +L 
Sbjct: 1344 QLIDNLKSTLEISQNKKDEFEIKLHSTEQYKQELQISLKEQDQKIKQLQQESYYLSKELD 1403

Query: 1354 TENQSY----KQMQEQSILNINEEN--AQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTH 1407
            TE Q +    K++ E ++   N++N   Q                 +++    ++ +L  
Sbjct: 1404 TEQQKHTTQKKKVNELTVQIQNKDNELQQQINKLKNLEEQILKKDQQISTLNNQISQLKQ 1463

Query: 1408 QLELKDSEIYQKTHEYTITLT-QRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKM 1466
            +     +EI  K ++     T ++N   +++++Q V+ E++I  +T EK      L+ K 
Sbjct: 1464 ENNKYTNEIIPKLNQQIDQETLEKNQLHKSLQEQFVQMEQQILSMTREKSP----LKSKS 1519

Query: 1467 HENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTAL 1526
            +     ++    E   ++ ++I + N  I + +   K + + N  L  ++ K N+    L
Sbjct: 1520 NSQCKPFDQSLNEKITQQEQIINQKNQIIEQQLEKLKILTQQNNGLLHQINKLNDDLRDL 1579

Query: 1527 ENQEIEI 1533
            +++   +
Sbjct: 1580 QDKSFSL 1586



 Score =  107 bits (256), Expect = 3e-21
 Identities = 203/1038 (19%), Positives = 444/1038 (42%), Gaps = 110/1038 (10%)

Query: 213  DTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRIS-SLEEANKLLEAARFEISLEH 271
            + KQ   ++Q+  +  + E +  +Q  L D++ ++ ++S  +  + +  E+  F  + + 
Sbjct: 928  ENKQLNVQIQKLQLQYDTEIR-RQQTQLSDLQFENNKLSREVTYSKQYSESVVFNQTEKK 986

Query: 272  SKLAQELE-QXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIEL 330
               +QE E                + + + + S EE  ++  K  LE  NM E+   I+ 
Sbjct: 987  QYSSQESEIVQLKNQLADKTHQLKVIQTNSQNSMEELQQVISKLGLENKNMNEVHNSIK- 1045

Query: 331  LEHLNCQIRQTNKELENK---LATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWS 387
               L  Q+ +  ++L  K   +  +  E +     +K+    +  KS +      ++   
Sbjct: 1046 -SRLEAQVNKLVEQLREKDQNINKIQDELRRKEQIAKQQEDDLFIKSNQVEQLIQQNKGL 1104

Query: 388  QLSSETLN---QDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXG 444
             L    LN   Q+       +  +K  + ++      +  E  I                
Sbjct: 1105 ALQLNNLNFELQELRMASLSHSFSKSHIDVRENENQELQSEIQILRNQIQTLESQSTKQL 1164

Query: 445  KDTLIAQLQLEHQQHMEGPSLIH--VGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLI 502
             ++ + +L+ E   +    SLI   +    ED     +   Q +Q++    K+++ K   
Sbjct: 1165 DNSKLIKLEDEIVHYQREISLIKNKLQITLEDSEFYKREFTQSQQQIEKMRKELSQKQS- 1223

Query: 503  EKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTID----NFSKVSDSNKEIV 558
            EKL + E ++ Q    I   N+ +I+  S+  + ++  Q+ ID    + ++  +SN+ I 
Sbjct: 1224 EKLSTQENELVQ----IKRTNQQLIQENSDQSITIQNQQQQIDELQQDLNEYIESNQTIT 1279

Query: 559  RLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMI--ESDVYKKMIEMENLAETRLKAI 616
            +L  +L    +K   L+ E   L + + +  S + +  + ++ + + +++++ + + K I
Sbjct: 1280 KLKMQLQLEGEK---LQRENQQLIIKIQELSSQKQMGRDQELNELIRKLQSMEQDKAKLI 1336

Query: 617  SLLESQKF---DLVQELHILQQKYDEVEDKL---------ADISQLQSDQVCSEIK--SV 662
               E Q+    +L   L I Q K DE E KL           IS  + DQ   +++  S 
Sbjct: 1337 ISCEQQQQLIDNLKSTLEISQNKKDEFEIKLHSTEQYKQELQISLKEQDQKIKQLQQESY 1396

Query: 663  HLEEQIDAL----SASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENM 718
            +L +++D      +  KK++  +   ++    +L   I  L+N +E I+ K Q     N 
Sbjct: 1397 YLSKELDTEQQKHTTQKKKVNELTVQIQNKDNELQQQINKLKNLEEQILKKDQQISTLNN 1456

Query: 719  DLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRI 778
             ++ +L++ + +  +E++ K+N +   +   +  +   +QE+ + +E     +++ KS +
Sbjct: 1457 QIS-QLKQENNKYTNEIIPKLNQQIDQETLEKNQLHKSLQEQFVQMEQQILSMTREKSPL 1515

Query: 779  CRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVE 838
                 S     D+  SL  K  Q    + +K +      I E +L  +L +L   +  + 
Sbjct: 1516 KSKSNSQCKPFDQ--SLNEKITQQEQIINQKNQ------IIEQQL-EKLKILTQQNNGLL 1566

Query: 839  KQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNA-----LVEKANRTDLAESES 893
             Q+ ++  + ++LQ K+  L   ++   I+ S     YNA     L  +    D+ ES+ 
Sbjct: 1567 HQINKLNDDLRDLQDKSFSLDRSSETYLINKS-FNSKYNADNDLILQHQYQSQDIYESDR 1625

Query: 894  TKYQTQLRDLESNLKRITHEHQTL---IVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKY 950
             K Q+Q +  E  L+    E+++L   I Q K+ I+  + ++  QI++      +  ++ 
Sbjct: 1626 -KRQSQYQQFEQTLQESVQENKSLKLEIDQLKQFIQQQKNDYEKQIQNMSTSNSLQIQEL 1684

Query: 951  EKNIEYVTQLEAQLQ---------EYKNNIENLN------MNVEELN-KMNLEL---IDK 991
               +E ++Q E + Q         EY+  I+ L         VE+ N ++N E+   I K
Sbjct: 1685 NTKLEKLSQEEKKHQNMPSQNLRNEYQQQIDRLEEELLRKQGVEQSNQRLNNEIKIQITK 1744

Query: 992  HVQKQQTQSP--DYTEQYINEINKLNALLK---------------QKDEEIIALNQKINN 1034
             V+ QQ         +Q  N+I +   L++               QK+ E+  L Q++ N
Sbjct: 1745 VVELQQQLEGLRQQNQQLSNQIKEQEELIRSLQKMKIQNSDSSEAQKEGELNQLTQQLQN 1804

Query: 1035 AQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKE 1094
              +        Y+ +++++ +K+E +E E+Q+ S+Q+  S + ++     V + + + K+
Sbjct: 1805 ETLILKGQNQKYQQQISEYQSKIETLENEIQKKSQQI--SLKDSQ-----VNQNNRKTKK 1857

Query: 1095 LKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEE--EEFIQ 1152
            L+E     +  +    G++  +  E +    N ++            +K  +E  +   +
Sbjct: 1858 LEEQIQLLQDQLKGQGGLVTQNKDEVIVQLQNELEQKRTEMFEFQKQIKQLDEQIDRLTK 1917

Query: 1153 ERSVLQEQSAKLNTELQE 1170
              S L E++ +LN +L++
Sbjct: 1918 SNSALMEENCRLNDQLKD 1935


>UniRef50_Q4RQ56 Cluster: Chromosome 17 SCAF15006, whole genome
            shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 17
            SCAF15006, whole genome shotgun sequence - Tetraodon
            nigroviridis (Green puffer)
          Length = 1962

 Score =  149 bits (362), Expect = 5e-34
 Identities = 299/1535 (19%), Positives = 629/1535 (40%), Gaps = 135/1535 (8%)

Query: 140  QLGDVTHLSNTIKEKDNALSVLQVKMKIMETT------ILDLQEKINE----KDQIIEAK 189
            QLGD  +L   + E+D  + + + K ++ ET       +  L+ ++ +    K++I E K
Sbjct: 315  QLGDAKNLIEQL-EQDKGMVIAETKRQMHETLEMKEDEVAQLRSRLQQVTALKEEIQEQK 373

Query: 190  NKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEK---QRLLKDIESK 246
             KA                   E  KQ   +++E    +E   ++E+   Q++L  ++ +
Sbjct: 374  EKAEKSAFEELERALGVAQRAEEARKQLQVQLEEQVKEVERASEEERKSLQQVLTRVKQE 433

Query: 247  DVRI--SSLEEANKLLEAARFE--ISLEH---SKLAQELEQXXXXXXXXXXXXXXLAKQS 299
             V I   S EE    LE    E  ++ E    +++ + +EQ               A  +
Sbjct: 434  VVTIMKKSSEETVANLEKLHSEALVAKEEEMSARMDKAVEQCREEFAQLAKEREQQASLA 493

Query: 300  IEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTE-SKA 358
            +E +  +KT +  +    I    EL  ++E  +    ++  T +++  + + M  E S  
Sbjct: 494  LEDAELQKTALRTEADNRIK---ELQFELEAAKTRILELESTQEKISQEESKMSHEFSGQ 550

Query: 359  VSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKL----EMVI 414
            V     K    IS    ++     K   + +       +  K+ ++ E+ KL    ++ +
Sbjct: 551  VVELKDKHQEQISALEDKHQEQLEKHTDTLIKQHNAALEELKEKHREELEKLLRDTDVQL 610

Query: 415  QSLNKDLVDK-----EYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVG 469
            Q   ++L  K     E + +E D            K  L+ Q  L  +         H  
Sbjct: 611  QGRVEELTQKAAEKMEVMQAELDRVSTELSEALNTKQ-LLEQKVLAAEDACRLAREEH-D 668

Query: 470  TNTEDVNEIAKVQ-EQLKQELNDEI--KDVNVKDLIEKLKSAEEQITQLNDEIDAANKNM 526
               ++  E  K++   +KQE  + +   +  +K+ +  LK  E +  +  +E+ A  K +
Sbjct: 669  KKFQEWEEKHKLELTNIKQEHEESLGGMEKTLKEEVNALKIVEGERQKEIEELTAREKTL 728

Query: 527  IKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLV 586
            I+     K+K+K++++   + S+    N+ +     EL  +S+K+ + E++  +L+ H +
Sbjct: 729  IEESHELKVKVKELEELQQSLSQSLQENERLKDSNAELSKISEKLEQCEKDYTDLE-HQL 787

Query: 587  DYDSGRMIESDVYKKMIEMEN-LAETRLKAISLLESQKFDL-VQELHILQQKYDEVEDKL 644
            +       E D  K + E++N L + R + +   +S    L  +E      K    E+K 
Sbjct: 788  NAAKNGCQEKD--KLLEELQNQLHQNRTELLEQEKSFTAQLNTKEEEKTSLKKQLEEEKA 845

Query: 645  ADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIK-DLENDK 703
            A   +LQS     E K   LE ++D      K++    E+ K   +    T+K +LE   
Sbjct: 846  AHEKKLQSTVSGMEAKVKALETKLDKFKQKAKDMH---ESAKKKLQTQEETMKMELEKKD 902

Query: 704  EDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLY 763
            ++I  K Q   ++ +++  K  +  +  ++EL A  NH+E+ +         K++E   +
Sbjct: 903  KEIHLKEQQIQEKIIEMAQKSSEGLSSAVTELQA--NHKEELE---------KLRESHQH 951

Query: 764  -IENIESELS-KYKSRICRLEESIA-VMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQE 820
             +EN+E   + K + +   L E  +  ++++ + LE  + QL    +E ++  SE    +
Sbjct: 952  EVENLEHRWNEKLRQQEEELSEKHSNALQEKMHELEEVSQQLSRSKEETEQVSSESKGLK 1011

Query: 821  DELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALV 880
            ++L  R   +    + ++++L E   + + L +   +L E+ ++++ +L+       AL 
Sbjct: 1012 EDLAIRDTTV----QKLQEELNEAAVKLESLSRAELLLKEQMESVERNLN------QALS 1061

Query: 881  EKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAI 940
            E+ +  D   S +  ++ +L+ L   LK+   + + L   + KE +DL+    T+ ES +
Sbjct: 1062 ERNSLQDQLTSANRDHEEKLKSLSHELKKAEEQIKLLQGVRSKESKDLK----TKSESVV 1117

Query: 941  RDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQS 1000
            + + VLN K E        L  Q +E KN   +L+    ++N   +E +    Q+++  +
Sbjct: 1118 QLQAVLNSKEELICTLEENLRQQAEENKNLCISLDQLTAQVN-AQMEHVTALTQEKENHA 1176

Query: 1001 PDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENM 1060
               +E+ +  I +L+   +   E + A    I N +     + +  ES   +  T +  +
Sbjct: 1177 LSLSEK-VQNIQELSEANRSITESVKANESHITNLESIISDLKTQLESSTNEKETTVSLL 1235

Query: 1061 EEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIIS--STI 1118
             ++     +Q   + +  E+ +    E+ D ++            + +++G I S  + +
Sbjct: 1236 MQQYAEEKQQAAGTIERLEQERKSALEEADVLRSSLSDHQNQAERLAQSDGTIASLQARL 1295

Query: 1119 EPMSDD--ANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKII 1176
            E +  +    N D            +   E ++ + E+    ++ + L +EL  C  ++ 
Sbjct: 1296 EELQREICEKNEDVQRLTASIDDQSISKSEMDQVLSEK---DQKVSGLTSELDRCLGRLG 1352

Query: 1177 QLE------TLNTELTGHDVVN-----QEQINQLKSKLEQLNTENDNLLSTVAELRSSIS 1225
            +LE      T   E    D+       + +   L  +L+Q   E+    +   E+   +S
Sbjct: 1353 ELEEQLALKTRECEQVAADLQQERSAWEREKKVLAEELQQTQVEHSQSSNLEQEMGERLS 1412

Query: 1226 SAVDQRGFEIAELWKQHLAQREADFQKTEHEL-RVQLSAFESKYEQLLDSVQSSTQEETN 1284
            S  +       + W++ L     +FQK + EL R +  +  +  E+L   V     E   
Sbjct: 1413 SLREDN-----QKWQRQLESEREEFQKIKDELIREKEESLRTAEEKLSAEVGRKVSELKK 1467

Query: 1285 KI-VTMEQV-TSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIE--DEKV-AFXXXXX 1339
            K    + Q+   L ++L++KE+ +  LQ    +V N     +   E  +EK+        
Sbjct: 1468 KAEQKISQIRKQLLSQLEEKEQTMATLQASLEEVKNSETAQKQHTEALEEKIRTSEEALA 1527

Query: 1340 XXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAE 1399
                       +L ++ +  K+   + +   NEE   L +               + D E
Sbjct: 1528 RLKEEQEKQLEELLSKEKHEKEKSLEDLRKANEEKLSLLERETERAEELKQTQSSLRDIE 1587

Query: 1400 AKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESEL 1459
            A+  E   Q E           +  + + +  +E +    QL ++ + I  L    ++E 
Sbjct: 1588 ARFKETLEQNE-----------KLQVEVNRLKEEIQEKESQLCQHGETIRQLQLRSDAEA 1636

Query: 1460 AILRLKMHEN----ANHYETMQKES---EIERVKLIEELNVK---ITESVSLNKQVAELN 1509
            A+ R  + +     ANH    ++++   E  + KL++  N K     + + L K +  L 
Sbjct: 1637 AVERSSVQQAGSAVANHAPGEEEDADSVECLKSKLMQMKNEKDKIHKDFIRLQKDMRSLR 1696

Query: 1510 KALEE--EVAKTNEMQTALE--NQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTK 1565
            K  E+  E  K   M+ + +    E+E V +       Q +   +S +  K        K
Sbjct: 1697 KEHEQDLEFLKKELMEESEQKLKGELEDVQMKHNSAIKQLLREFNSKEALKDTEIDLAVK 1756

Query: 1566 QGRDEQLDNTMNKELLDAVPRAELDLAMYMLHQRD 1600
            +  ++     +  EL+D + R E+     ++ Q+D
Sbjct: 1757 EAIEKA--QVVEAELMD-IHRDEVSQLKQLIAQKD 1788



 Score =  128 bits (310), Expect = 9e-28
 Identities = 238/1222 (19%), Positives = 509/1222 (41%), Gaps = 89/1222 (7%)

Query: 143  DVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXX 202
            ++  +S  + E  N   +L+ K+   E      +E+ ++K Q  E K+K           
Sbjct: 631  ELDRVSTELSEALNTKQLLEQKVLAAEDACRLAREEHDKKFQEWEEKHKLELTNIKQEHE 690

Query: 203  XXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQR-LLKDIESKDVRISSLEE-----A 256
                        +    K+ E     E E    +++ L+++     V++  LEE     +
Sbjct: 691  ESLGGMEKTLKEEVNALKIVEGERQKEIEELTAREKTLIEESHELKVKVKELEELQQSLS 750

Query: 257  NKLLEAARFEIS-LEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGS 315
              L E  R + S  E SK++++LEQ               AK      C+EK ++ E   
Sbjct: 751  QSLQENERLKDSNAELSKISEKLEQCEKDYTDLEHQLNA-AKNG----CQEKDKLLE--- 802

Query: 316  LEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSG 375
             E+ N      + ELLE       Q N + E K +      +  ++  KK    +S    
Sbjct: 803  -ELQNQLH-QNRTELLEQEKSFTAQLNTKEEEKTSLKKQLEEEKAAHEKKLQSTVSGMEA 860

Query: 376  RNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXX 435
            +  A + K    +  ++ +++   KK+   E   ++M ++  +K++  KE  I EK    
Sbjct: 861  KVKALETKLDKFKQKAKDMHESAKKKLQTQE-ETMKMELEKKDKEIHLKEQQIQEK--II 917

Query: 436  XXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKD 495
                    G  + + +LQ  H++ +E     H     E  N   +  E+L+Q+  +E+ +
Sbjct: 918  EMAQKSSEGLSSAVTELQANHKEELEKLRESH---QHEVENLEHRWNEKLRQQ-EEELSE 973

Query: 496  VNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNK 555
             +   L EK+   EE   QL+      +K   +  S+    LK+     D  + V    +
Sbjct: 974  KHSNALQEKMHELEEVSQQLS-----RSKEETEQVSSESKGLKEDLAIRD--TTVQKLQE 1026

Query: 556  EIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKA 615
            E+     +L  LS+    L+E+  +++ +L    S R   + +  ++       E +LK+
Sbjct: 1027 ELNEAAVKLESLSRAELLLKEQMESVERNLNQALSER---NSLQDQLTSANRDHEEKLKS 1083

Query: 616  ISLLESQKFDLVQELHILQQKYD-EVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSAS 674
            +S    +  + ++ L  ++ K   +++ K   + QLQ+     E     LEE +   +  
Sbjct: 1084 LSHELKKAEEQIKLLQGVRSKESKDLKTKSESVVQLQAVLNSKEELICTLEENLRQQAEE 1143

Query: 675  KKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISE 734
             K L + ++ L          +  L  +KE+    L   +Q   +L++    ++ E +  
Sbjct: 1144 NKNLCISLDQLTAQVNAQMEHVTALTQEKENHALSLSEKVQNIQELSEANRSIT-ESVKA 1202

Query: 735  LLAKINHEEQ--SKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRR 792
              + I + E   S ++TQ  +++   E++  +  +  + ++ K +     E +   ++R+
Sbjct: 1203 NESHITNLESIISDLKTQ--LESSTNEKETTVSLLMQQYAEEKQQAAGTIERLE--QERK 1258

Query: 793  YSLERKADQLGSYLQEKQK-----AYSEYTIQ--EDELVNRLAVLMDHDRVVEKQLLEIE 845
             +LE +AD L S L + Q      A S+ TI   +  L      + + +  V++    I+
Sbjct: 1259 SALE-EADVLRSSLSDHQNQAERLAQSDGTIASLQARLEELQREICEKNEDVQRLTASID 1317

Query: 846  HENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLES 905
             ++    + +Q+L E++Q +    S++ +    L E   +  L   E  +    L+    
Sbjct: 1318 DQSISKSEMDQVLSEKDQKVSGLTSELDRCLGRLGELEEQLALKTRECEQVAADLQQ--- 1374

Query: 906  NLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQ 965
              +R   E +  ++ ++ +   +E   ++ +E  + ++  L+   E N ++  QLE++ +
Sbjct: 1375 --ERSAWEREKKVLAEELQQTQVEHSQSSNLEQEMGER--LSSLREDNQKWQRQLESERE 1430

Query: 966  EYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINK-LNALLKQKDEE 1024
            E++   + L    EE  +   E +   V ++ ++     EQ I++I K L + L++K++ 
Sbjct: 1431 EFQKIKDELIREKEESLRTAEEKLSAEVGRKVSELKKKAEQKISQIRKQLLSQLEEKEQT 1490

Query: 1025 IIALN---QKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEE- 1080
            +  L    +++ N++ +        E K+      L  ++EE ++  ++LL  ++H +E 
Sbjct: 1491 MATLQASLEEVKNSETAQKQHTEALEEKIRTSEEALARLKEEQEKQLEELLSKEKHEKEK 1550

Query: 1081 -LQILVREQDDQIKEL-KETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXX 1138
             L+ L +  ++++  L +ET+   E+   ++    I +  +   +    +          
Sbjct: 1551 SLEDLRKANEEKLSLLERETERAEELKQTQSSLRDIEARFKETLEQNEKLQVEVNRLKE- 1609

Query: 1139 XXXLKVQEEE-EFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQIN 1197
                ++QE+E +  Q    +++   + + E     + + Q  +        +  + + + 
Sbjct: 1610 ----EIQEKESQLCQHGETIRQLQLRSDAEAAVERSSVQQAGSAVANHAPGEEEDADSVE 1665

Query: 1198 QLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREA-------DF 1250
             LKSKL Q+  E D +      L+  + S   +   ++  L K+ + + E        D 
Sbjct: 1666 CLKSKLMQMKNEKDKIHKDFIRLQKDMRSLRKEHEQDLEFLKKELMEESEQKLKGELEDV 1725

Query: 1251 Q-KTEHELRVQLSAFESKYEQLLDS-VQSSTQEETNKIVTME---------QVTSLQNKL 1299
            Q K    ++  L  F SK E L D+ +  + +E   K   +E         +V+ L+  +
Sbjct: 1726 QMKHNSAIKQLLREFNSK-EALKDTEIDLAVKEAIEKAQVVEAELMDIHRDEVSQLKQLI 1784

Query: 1300 QDKEEHLRNLQEKYADVINQIE 1321
              K+E L+   +KY  VI   E
Sbjct: 1785 AQKDEELQKNVQKYEQVIQSRE 1806



 Score =  110 bits (265), Expect = 3e-22
 Identities = 172/887 (19%), Positives = 385/887 (43%), Gaps = 83/887 (9%)

Query: 697  KDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAK 756
            KD E  +  +       ++   +L + L+ +    ++    ++  ++Q+K   Q   DA 
Sbjct: 117  KDKEKTQVILSQSQDKSLRRIGELREVLKSLLNVAVAWGQKELQMDQQAKKHLQEEFDAA 176

Query: 757  IQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEY 816
            ++E+D  I  ++++++  K R+  + +  A +E      E  A+       +KQ    E 
Sbjct: 177  LEEKDQMITVLQTQVALLKKRMKGVSDGAAPLEGDVNQAENAAESSPQSPSKKQGEEPEA 236

Query: 817  TIQE--DELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQ 874
            T  E   +    +  L    +  E  L + +   +  ++++  L  EN+ LQ  L +  Q
Sbjct: 237  TEGEGNSDPAKDMEALQKRVKRQENLLQKCKEIMRTHKERSAQLSTENETLQEQLQERLQ 296

Query: 875  HYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEI-EDLEIEFN 933
                 +EK    +L  +E TK  TQL D ++ ++++  +   +I + K+++ E LE++ +
Sbjct: 297  E----LEKIK--ELHTTEKTKLITQLGDAKNLIEQLEQDKGMVIAETKRQMHETLEMKED 350

Query: 934  --TQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDK 991
               Q+ S ++    L E+ ++  E   +   +  E    +        +  ++ LE   K
Sbjct: 351  EVAQLRSRLQQVTALKEEIQEQKEKAEKSAFEELERALGVAQRAEEARKQLQVQLEEQVK 410

Query: 992  HVQKQQTQSPDYTEQYINEI-NKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKL 1050
             V++   +     +Q +  +  ++  ++K+  EE +A  +K+++      ++V+  E   
Sbjct: 411  EVERASEEERKSLQQVLTRVKQEVVTIMKKSSEETVANLEKLHSE-----ALVAKEEEMS 465

Query: 1051 AQFTTKLENMEEEMQRVSK---QLLDSKQHNEELQ--ILVREQDDQIKELKETKLTFEMN 1105
            A+    +E   EE  +++K   Q       + ELQ   L  E D++IKEL+     FE+ 
Sbjct: 466  ARMDKAVEQCREEFAQLAKEREQQASLALEDAELQKTALRTEADNRIKELQ-----FELE 520

Query: 1106 IPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAK-L 1164
              KT  + + ST E +S + + +             LK + +E+        QEQ  K  
Sbjct: 521  AAKTRILELESTQEKISQEESKM---SHEFSGQVVELKDKHQEQISALEDKHQEQLEKHT 577

Query: 1165 NTELQECYTKIIQL-----ETLNTELTGHDVVNQEQINQL----KSKLEQLNTENDNLLS 1215
            +T +++    + +L     E L   L   DV  Q ++ +L      K+E +  E D + +
Sbjct: 578  DTLIKQHNAALEELKEKHREELEKLLRDTDVQLQGRVEELTQKAAEKMEVMQAELDRVST 637

Query: 1216 TVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSV 1275
             ++E  ++    ++Q+     +  +    + +  FQ+ E + +++L+  + ++E+ L  +
Sbjct: 638  ELSEALNT-KQLLEQKVLAAEDACRLAREEHDKKFQEWEEKHKLELTNIKQEHEESLGGM 696

Query: 1276 QSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFX 1335
            + + +EE N +  +E       + Q + E L   ++   +  +++++   E+E+ + +  
Sbjct: 697  EKTLKEEVNALKIVE------GERQKEIEELTAREKTLIEESHELKVKVKELEELQQSLS 750

Query: 1336 XXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRV 1395
                               EN+  K    + +  I+E+  Q +K                
Sbjct: 751  QSL---------------QENERLKDSNAE-LSKISEKLEQCEKDYTDLEHQLNAAKNGC 794

Query: 1396 NDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVE----YEKRIEDL 1451
             + +  + EL +QL    +E+ ++   +T  L  + +E  ++++QL E    +EK+++  
Sbjct: 795  QEKDKLLEELQNQLHQNRTELLEQEKSFTAQLNTKEEEKTSLKKQLEEEKAAHEKKLQST 854

Query: 1452 TYEKESELAILRLK----------MHENA-NHYETMQKESEIERVKLIEELNVKITESVS 1500
                E+++  L  K          MHE+A    +T ++  ++E  K  +E+++K  E   
Sbjct: 855  VSGMEAKVKALETKLDKFKQKAKDMHESAKKKLQTQEETMKMELEKKDKEIHLK--EQQI 912

Query: 1501 LNKQVAELNKALEEEVAKTNEMQTALENQEIEIV--TLNDEITNLQN 1545
              K +    K+ E   +   E+Q A   +E+E +  +   E+ NL++
Sbjct: 913  QEKIIEMAQKSSEGLSSAVTELQ-ANHKEELEKLRESHQHEVENLEH 958



 Score =  103 bits (248), Expect = 3e-20
 Identities = 214/1043 (20%), Positives = 437/1043 (41%), Gaps = 100/1043 (9%)

Query: 550  VSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLA 609
            +S S  + +R   EL  + + +  +    G  +L + D  + + ++ +    + E + + 
Sbjct: 126  LSQSQDKSLRRIGELREVLKSLLNVAVAWGQKELQM-DQQAKKHLQEEFDAALEEKDQMI 184

Query: 610  ETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQID 669
                  ++LL+ +   +      L+   ++ E+      Q  S +   E ++   E   D
Sbjct: 185  TVLQTQVALLKKRMKGVSDGAAPLEGDVNQAENAAESSPQSPSKKQGEEPEATEGEGNSD 244

Query: 670  A---LSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEK 726
                + A +K +    ENL    +++  T K+           LQ  +QE      +L++
Sbjct: 245  PAKDMEALQKRVKRQ-ENLLQKCKEIMRTHKERSAQLSTENETLQEQLQE------RLQE 297

Query: 727  MSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICR-LEESI 785
            +  EKI EL    +  E++K+ TQ G DAK       IE +E +     +   R + E++
Sbjct: 298  L--EKIKEL----HTTEKTKLITQLG-DAK-----NLIEQLEQDKGMVIAETKRQMHETL 345

Query: 786  AVMEDRRYSLERKADQLGSYLQE--KQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLE 843
             + ED    L  +  Q+ +  +E  +QK  +E +  E EL   L V    +   ++  ++
Sbjct: 346  EMKEDEVAQLRSRLQQVTALKEEIQEQKEKAEKSAFE-ELERALGVAQRAEEARKQLQVQ 404

Query: 844  IEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESE---STKYQTQL 900
            +E + KE+++ ++   EE ++LQ  L+ ++Q    +++K++   +A  E   S     + 
Sbjct: 405  LEEQVKEVERASE---EERKSLQQVLTRVKQEVVTIMKKSSEETVANLEKLHSEALVAKE 461

Query: 901  RDLESNLKRITHEHQTLIVQKKKEIE---DLEIEFNTQIESAIR---DKKVLNEKYEKNI 954
             ++ + + +   + +    Q  KE E    L +E     ++A+R   D ++   ++E   
Sbjct: 462  EEMSARMDKAVEQCREEFAQLAKEREQQASLALEDAELQKTALRTEADNRIKELQFELEA 521

Query: 955  EYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQ-------KQQTQSPDYTEQY 1007
                 LE +  + K + E   M+  E +   +EL DKH +       K Q Q   +T+  
Sbjct: 522  AKTRILELESTQEKISQEESKMS-HEFSGQVVELKDKHQEQISALEDKHQEQLEKHTDTL 580

Query: 1008 INEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRV 1067
            I + N     LK+K  E   L + + +  V     V +   K A+   K+E M+ E+ RV
Sbjct: 581  IKQHNAALEELKEKHRE--ELEKLLRDTDVQLQGRVEELTQKAAE---KMEVMQAELDRV 635

Query: 1068 SKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANN 1127
            S +L ++    + L+  V   +D  +  +E     +    + E            +   +
Sbjct: 636  STELSEALNTKQLLEQKVLAAEDACRLARE---EHDKKFQEWEEKHKLELTNIKQEHEES 692

Query: 1128 VDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTG 1187
            +             LK+ E E     +  ++E +A+  T ++E +           EL  
Sbjct: 693  LGGMEKTLKEEVNALKIVEGE----RQKEIEELTAREKTLIEESH-----------ELK- 736

Query: 1188 HDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQRE 1247
               V  +++ +L+  L Q   EN+ L  + AEL S IS  ++Q   +  +L  Q  A + 
Sbjct: 737  ---VKVKELEELQQSLSQSLQENERLKDSNAEL-SKISEKLEQCEKDYTDLEHQLNAAKN 792

Query: 1248 ADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKL-QDKEEHL 1306
               +K +    +Q    +++ E LL+  +S T +   K    E+ TSL+ +L ++K  H 
Sbjct: 793  GCQEKDKLLEELQNQLHQNRTE-LLEQEKSFTAQLNTK---EEEKTSLKKQLEEEKAAHE 848

Query: 1307 RNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQS 1366
            + LQ   + +  +++ L ++++  K                    ++ E +   +     
Sbjct: 849  KKLQSTVSGMEAKVKALETKLDKFKQKAKDMHESAKKKLQTQEETMKMELEKKDKEIHLK 908

Query: 1367 ILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSE------IYQKT 1420
               I E+  ++ + S              +  E + L  +HQ E+++ E      + Q+ 
Sbjct: 909  EQQIQEKIIEMAQKSSEGLSSAVTELQANHKEELEKLRESHQHEVENLEHRWNEKLRQQE 968

Query: 1421 HE----YTITLTQRNDEFENVRQQLVEYEKRIEDLTYEK---ESELAILRL---KMHENA 1470
             E    ++  L ++  E E V QQL   ++  E ++ E    + +LAI      K+ E  
Sbjct: 969  EELSEKHSNALQEKMHELEEVSQQLSRSKEETEQVSSESKGLKEDLAIRDTTVQKLQEEL 1028

Query: 1471 NHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQE 1530
            N  E   K   + R +L+ +  ++  E  +LN+ ++E N   ++  +   + +  L++  
Sbjct: 1029 N--EAAVKLESLSRAELLLKEQMESVER-NLNQALSERNSLQDQLTSANRDHEEKLKSLS 1085

Query: 1531 IEIVTLNDEITNLQNMVRASSSK 1553
             E+    ++I  LQ  VR+  SK
Sbjct: 1086 HELKKAEEQIKLLQG-VRSKESK 1107



 Score = 89.4 bits (212), Expect = 7e-16
 Identities = 172/967 (17%), Positives = 396/967 (40%), Gaps = 81/967 (8%)

Query: 155  DNALSVLQVKMKIMETTILDLQEKINEKDQIIEAK--NKATTXXXXXXXXXXXXXXXXXE 212
            ++A   LQ + + M+  +    ++I+ K+Q I+ K    A                   E
Sbjct: 881  ESAKKKLQTQEETMKMELEKKDKEIHLKEQQIQEKIIEMAQKSSEGLSSAVTELQANHKE 940

Query: 213  DTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESK-----DVRISSLEEANKLLEAARFEI 267
            + ++     Q     +E  W ++ ++  +++  K       ++  LEE ++ L  ++ E 
Sbjct: 941  ELEKLRESHQHEVENLEHRWNEKLRQQEEELSEKHSNALQEKMHELEEVSQQLSRSKEET 1000

Query: 268  SLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKK 327
                S+     E               L + +++     + E+  K  +E      L + 
Sbjct: 1001 EQVSSESKGLKEDLAIRDTTVQKLQEELNEAAVKLESLSRAELLLKEQMESVERN-LNQA 1059

Query: 328  IELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSG--RNTASKMKSP 385
            +     L  Q+   N++ E KL ++  E K      K    + S++S   +  +  +   
Sbjct: 1060 LSERNSLQDQLTSANRDHEEKLKSLSHELKKAEEQIKLLQGVRSKESKDLKTKSESVVQL 1119

Query: 386  WSQLSSE-----TLNQDTDKKI--NKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXX 438
             + L+S+     TL ++  ++   NKN    L+ +   +N  +     +  EK+      
Sbjct: 1120 QAVLNSKEELICTLEENLRQQAEENKNLCISLDQLTAQVNAQMEHVTALTQEKENHALSL 1179

Query: 439  XXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNV 498
                     L    +   +      S  H+ TN E +  I+ ++ QL+   N+  K+  V
Sbjct: 1180 SEKVQNIQELSEANRSITESVKANES--HI-TNLESI--ISDLKTQLESSTNE--KETTV 1232

Query: 499  KDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIV 558
              L+++    ++Q     + ++   K+ ++     +  L   Q   +   +++ S+  I 
Sbjct: 1233 SLLMQQYAEEKQQAAGTIERLEQERKSALEEADVLRSSLSDHQNQAE---RLAQSDGTIA 1289

Query: 559  RLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGR----MIESDVYKKMIEMENLAETRLK 614
             L   L  L +++ E  E+   L   + D    +     + S+  +K+  + +  +  L 
Sbjct: 1290 SLQARLEELQREICEKNEDVQRLTASIDDQSISKSEMDQVLSEKDQKVSGLTSELDRCLG 1349

Query: 615  AISLLESQKFDLVQELHI----LQQKYDEVE-DKLADISQLQSDQVCSEIKSVHLEEQI- 668
             +  LE Q     +E       LQQ+    E +K     +LQ  QV    +S +LE+++ 
Sbjct: 1350 RLGELEEQLALKTRECEQVAADLQQERSAWEREKKVLAEELQQTQV-EHSQSSNLEQEMG 1408

Query: 669  DALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDL-TDKLEKM 727
            + LS+ +++       L+ ++E+      +L  +KE+ +   +  +   +     +L+K 
Sbjct: 1409 ERLSSLREDNQKWQRQLESEREEFQKIKDELIREKEESLRTAEEKLSAEVGRKVSELKKK 1468

Query: 728  SAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAV 787
            + +KIS++  ++  + + K QT   + A ++E    ++N E+   ++      LEE I  
Sbjct: 1469 AEQKISQIRKQLLSQLEEKEQTMATLQASLEE----VKNSETAQKQHTEA---LEEKIRT 1521

Query: 788  MEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAV-LMDHDRVVEKQLLEIEH 846
             E+    L+ + ++    L  K+K   E ++++    N   + L++ +    ++L + + 
Sbjct: 1522 SEEALARLKEEQEKQLEELLSKEKHEKEKSLEDLRKANEEKLSLLERETERAEELKQTQS 1581

Query: 847  ENKELQKKNQILLEENQNLQISL-----------SDMQQHYNALVEKANRTDLAESESTK 895
              ++++ + +  LE+N+ LQ+ +           S + QH   + +   R+D   +    
Sbjct: 1582 SLRDIEARFKETLEQNEKLQVEVNRLKEEIQEKESQLCQHGETIRQLQLRSDAEAAVERS 1641

Query: 896  YQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIR---DKKVLNEKYEK 952
               Q     +N      E    +   K ++  ++ E +   +  IR   D + L +++E+
Sbjct: 1642 SVQQAGSAVANHAPGEEEDADSVECLKSKLMQMKNEKDKIHKDFIRLQKDMRSLRKEHEQ 1701

Query: 953  NIEYVTQ--LEAQLQEYKNNIENLNM--------------NVEELNKMNLELIDKH-VQK 995
            ++E++ +  +E   Q+ K  +E++ M              + E L    ++L  K  ++K
Sbjct: 1702 DLEFLKKELMEESEQKLKGELEDVQMKHNSAIKQLLREFNSKEALKDTEIDLAVKEAIEK 1761

Query: 996  QQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTT 1055
             Q    +  + + +E+++L  L+ QKDEE   L + +   +    S   +   ++ Q   
Sbjct: 1762 AQVVEAELMDIHRDEVSQLKQLIAQKDEE---LQKNVQKYEQVIQSREQEMGDRVWQVQK 1818

Query: 1056 KLENMEE 1062
            +LE ++E
Sbjct: 1819 ELEELQE 1825


>UniRef50_UPI0000498399 Cluster: Viral A-type inclusion protein
            repeat; n=1; Entamoeba histolytica HM-1:IMSS|Rep: Viral
            A-type inclusion protein repeat - Entamoeba histolytica
            HM-1:IMSS
          Length = 1387

 Score =  149 bits (361), Expect = 6e-34
 Identities = 224/1124 (19%), Positives = 490/1124 (43%), Gaps = 94/1124 (8%)

Query: 239  LLKD-IESKDVRISSLEEANKLLEAARFEIS-LEHSKLAQELEQXXXXXXXXXXXXXXLA 296
            L+KD IE   V ++++ E  +++E    E   +++  + QEL                L 
Sbjct: 280  LVKDKIEKLRVNVANMMEGLEMVEVEEDEFDEMDNDMIIQELNIHKGKIDNMMLEAMELV 339

Query: 297  KQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTES 356
            K+      E + E  +        + +  KKIE LE L   +++  +E E     M    
Sbjct: 340  KEESSTPIEIRGEDSQALEELRVQIKQKIKKIEELEKLVSVMKEKKEEAEKAEREM--RM 397

Query: 357  KAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKI--NKNEIAKLEMVI 414
            K  +  +  G      KS +    ++K    Q+       D +K I  NK +    E++I
Sbjct: 398  KCQNESTLMGIIEEFEKSVKELNDRIKEKNKQID------DYEKTIEENKEDFEAKELII 451

Query: 415  QSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTED 474
            Q L  +++       +K             + T   + Q + Q  ++      +    ++
Sbjct: 452  QQLKDEIIQLTNT-EQKLKEQLEIKEKELQEQTKEVKEQNQQQNIIQKKEQEIIDIKKKN 510

Query: 475  VNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHK 534
               I  +Q+++++E N+    + +K+L   +   EE++ ++ +  D   K + ++     
Sbjct: 511  EETIQLIQKEMEKERNE--LSIKIKELENIISGKEEEMNKIKEIHDYKEKEIQRITEKMN 568

Query: 535  LKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMI 594
             + +   KT    +K+ + N E      +++ L  ++   EEEKG  +L L +  + + I
Sbjct: 569  KETEINNKTQQELNKIKEENNEY---KNQINTLEIEIKTKEEEKGTTELELKE--NQKSI 623

Query: 595  ESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDE-VEDKLADISQLQSD 653
            +    K++ E E + +  +K   + E QK  +++E  + ++++ E VE+   +  + +S+
Sbjct: 624  QE--LKELKEQERINK-EIKEKEVKELQK--IIEEWKVKEKEWKEQVEENQKE--KEESE 676

Query: 654  QVCSEIKSV--HLEEQIDALSAS----KKELALVIENLKLDKEQLYGTIKDLENDKEDIM 707
            +  +++K +    EE++  L+       KE  ++ E +K + E++ G I+ L+  +    
Sbjct: 677  ENKNQMKRIIEKKEEEVKGLNQEIDKINKENEIMKEKMK-ELERIKGEIEVLKIKETGDS 735

Query: 708  NKLQNYIQENMDLTD--KLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIE 765
            N+ +  I+E     +  K +     K +E+  K  +EE ++ + +   D + +++++   
Sbjct: 736  NEYEKMIEELKKQIEIIKNDNEKERKNNEIEQKKKNEEFNQKEEELNNDIEKKKKEIEKL 795

Query: 766  NIESELSKYKSRICRLEESIAVMEDRRYSLERKA--DQLGSYLQEKQKAYSEYTIQEDEL 823
            N + E  K K+     E      +  + +L+++    +L S + EK +   E   +++  
Sbjct: 796  NKQIEELKQKNEENTKENIEKQNQINQLNLDKEKIMKELESTIMEKNQIEEERKKEQEIN 855

Query: 824  VNRLA-VLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALV-E 881
              ++  ++   D  + +    I    +E  KK   L + NQ L   +   ++  N  + E
Sbjct: 856  EKKINDIITSKDTKINELNKSIIELKEEWNKKENNLNKSNQELTEQIIQKEEIINVTIKE 915

Query: 882  KANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIR 941
              N   + E    K +T++ +L+  +K    E+   I +  KE E+++ EF  QI++  +
Sbjct: 916  NENLKKVKEEIEKKTETEINELQRKIK----ENNEQINEINKEKENIQKEFEIQIDNKNK 971

Query: 942  DKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSP 1001
            +   + EK EK I  +     ++ + KN +ENL   +E  N    E+I K  +K++    
Sbjct: 972  EINEIKEKNEKEINEIKIQIEEMNKEKNQLENLKKQLENEN----EIIKKENKKKE---- 1023

Query: 1002 DYTEQYINEINKLNALLKQKDEEIIALNQKINN------AQVSYMSMVSDYESKLAQ-FT 1054
                    E  ++  L+K+ +++I ++  +IN+       ++  + M+ + +  + + F 
Sbjct: 1024 -------EENKEMGYLIKENEKKIESIRNEINSKERELGTKIKLIEMIKNEKDIMEKDFK 1076

Query: 1055 TKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMII 1114
             +++N   E++R+    +D ++   ++ +++++ D+  K+  E K      I K     I
Sbjct: 1077 KEVDNKNIEIKRLQ---IDIEKKKNDITLIIQKNDEDKKKSIEEKKNLNQEIEK-----I 1128

Query: 1115 SSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTK 1174
             S    +  +   +              K Q E E +Q +   +     L  E+ E   K
Sbjct: 1129 KSEKNDVQKEKEQILLEKEDLQSDFNKYKTQMENEKLQIKEEHENNITNLQNEINE---K 1185

Query: 1175 IIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFE 1234
            I Q + +  ++   + +N +Q+++LK +L +   E +       E++  I  A      E
Sbjct: 1186 INQNDEIKLQI---EQLN-KQLDELKQQLVETQKEKEEETKKYEEVKGQIDGAHQ----E 1237

Query: 1235 IAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTS 1294
            +  + K+   +++ +  K E +  +Q + FE+K E+L   V+S    ET         T 
Sbjct: 1238 VENIKKE--TEQQINQMKKECD-EMQKTTFEAK-EELRVQVESVKMIETKVSTQKVSNTK 1293

Query: 1295 LQNKLQDKE---EHLRN-LQEKYADVINQIEILRSEIEDEKVAF 1334
            L+ ++++ E   E L+N   EK A    +   +  + ED+KV F
Sbjct: 1294 LKKRVEELERTIEKLKNERNEKEAFWEKKKMWMIEDEEDKKVLF 1337



 Score =  138 bits (335), Expect = 9e-31
 Identities = 241/1133 (21%), Positives = 488/1133 (43%), Gaps = 120/1133 (10%)

Query: 473  EDVNEIAKVQEQLKQELNDEIKD------VNVKDLIEKLKSAEEQITQLNDEIDAANKNM 526
            E + E+ K+ +  ++  ++ +KD      VNV +++E L+  E +     DE D  + +M
Sbjct: 261  ELIEELEKLMDICRKNTDELVKDKIEKLRVNVANMMEGLEMVEVE----EDEFDEMDNDM 316

Query: 527  IKVKSN-HKLKLKQMQKTIDNFSKVSDSNKEIVR-----LTEELH-HLSQKVAELEEEKG 579
            I  + N HK K+  M        K   S    +R       EEL   + QK+ ++EE + 
Sbjct: 317  IIQELNIHKGKIDNMMLEAMELVKEESSTPIEIRGEDSQALEELRVQIKQKIKKIEELE- 375

Query: 580  NLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHI-LQQKYD 638
                 LV     +  E++  ++ + M+   E+ L  I + E +K   V+EL+  +++K  
Sbjct: 376  ----KLVSVMKEKKEEAEKAEREMRMKCQNESTLMGI-IEEFEKS--VKELNDRIKEKNK 428

Query: 639  EVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKD 698
            +++D    I + + D    E+    L+++I  L+ ++++L    E L++ +++L    K+
Sbjct: 429  QIDDYEKTIEENKEDFEAKELIIQQLKDEIIQLTNTEQKLK---EQLEIKEKELQEQTKE 485

Query: 699  LENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQ 758
            ++   +   N +Q   QE +D+  K E+ + + I + + K  +E   KI+    I +  +
Sbjct: 486  VKEQNQQ-QNIIQKKEQEIIDIKKKNEE-TIQLIQKEMEKERNELSIKIKELENIISGKE 543

Query: 759  ERDLYIENIESELSKYKSRIC-RLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYT 817
            E    I+ I     K   RI  ++ +   +    +  L +  ++   Y  +      E  
Sbjct: 544  EEMNKIKEIHDYKEKEIQRITEKMNKETEINNKTQQELNKIKEENNEYKNQINTLEIEIK 603

Query: 818  IQEDELVNRLAVLMDHDRVVE--KQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQH 875
             +E+E       L ++ + ++  K+L E E  NKE+++K    ++E Q +       ++ 
Sbjct: 604  TKEEEKGTTELELKENQKSIQELKELKEQERINKEIKEKE---VKELQKIIEEWKVKEKE 660

Query: 876  YNALVEKANRTDLAESESTKYQT---------QLRDLESNLKRITHEHQTLIVQKKKEIE 926
            +   VE+ N+ +  ESE  K Q          +++ L   + +I  E++ ++ +K KE+E
Sbjct: 661  WKEQVEE-NQKEKEESEENKNQMKRIIEKKEEEVKGLNQEIDKINKENE-IMKEKMKELE 718

Query: 927  DLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVE-ELNKMN 985
             ++ E        I++    NE YEK IE   +L+ Q++  KN+ E    N E E  K N
Sbjct: 719  RIKGEIEVL---KIKETGDSNE-YEKMIE---ELKKQIEIIKNDNEKERKNNEIEQKKKN 771

Query: 986  LELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSD 1045
             E   K  +++     +  ++ I ++NK    LKQK+EE    N +  N Q++ +++  +
Sbjct: 772  EEFNQK--EEELNNDIEKKKKEIEKLNKQIEELKQKNEENTKENIEKQN-QINQLNLDKE 828

Query: 1046 YESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMN 1105
               K  + T   +N  EE +R  +Q ++ K+ N+    ++  +D +I EL ++ +  +  
Sbjct: 829  KIMKELESTIMEKNQIEE-ERKKEQEINEKKIND----IITSKDTKINELNKSIIELKEE 883

Query: 1106 IPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSV--LQ----- 1158
              K E  +  S  E         +             KV+EE E   E  +  LQ     
Sbjct: 884  WNKKENNLNKSNQELTEQIIQKEEIINVTIKENENLKKVKEEIEKKTETEINELQRKIKE 943

Query: 1159 --EQSAKLNTELQECYTKI-IQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLS 1215
              EQ  ++N E +    +  IQ++  N E+      N+++IN++K ++E++N E + L +
Sbjct: 944  NNEQINEINKEKENIQKEFEIQIDNKNKEINEIKEKNEKEINEIKIQIEEMNKEKNQLEN 1003

Query: 1216 TVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSV 1275
               +L +              E+ K+   ++E +      E+   +   E K E + + +
Sbjct: 1004 LKKQLENE------------NEIIKKENKKKEEE----NKEMGYLIKENEKKIESIRNEI 1047

Query: 1276 QSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFX 1335
             S  +E   KI  +E + + +  + +K+       +K  D  N IEI R +I+ EK    
Sbjct: 1048 NSKERELGTKIKLIEMIKN-EKDIMEKDF------KKEVDNKN-IEIKRLQIDIEKKKND 1099

Query: 1336 XXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRV 1395
                             + +    K ++E+   N+N+E  ++K                 
Sbjct: 1100 ITLIIQ-----------KNDEDKKKSIEEKK--NLNQEIEKIKSEKNDVQKEKEQILLEK 1146

Query: 1396 NDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQ--------RNDEFENVRQQLVEYEKR 1447
             D ++   +   Q+E +  +I ++ HE  IT  Q        +NDE +   +QL +    
Sbjct: 1147 EDLQSDFNKYKTQMENEKLQIKEE-HENNITNLQNEINEKINQNDEIKLQIEQLNKQLDE 1205

Query: 1448 IEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAE 1507
            ++    E + E      K  E     +   +E E  + +  +++N    E   + K   E
Sbjct: 1206 LKQQLVETQKEKEEETKKYEEVKGQIDGAHQEVENIKKETEQQINQMKKECDEMQKTTFE 1265

Query: 1508 LNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSF 1560
              + L  +V     ++T +  Q++    L   +  L+  +    ++  +  +F
Sbjct: 1266 AKEELRVQVESVKMIETKVSTQKVSNTKLKKRVEELERTIEKLKNERNEKEAF 1318



 Score =  138 bits (333), Expect = 2e-30
 Identities = 198/1041 (19%), Positives = 464/1041 (44%), Gaps = 72/1041 (6%)

Query: 573  ELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHI 632
            EL EE   L + +   ++  +++  + K  + + N+ E  L+ + + E  +FD +    I
Sbjct: 261  ELIEELEKL-MDICRKNTDELVKDKIEKLRVNVANMMEG-LEMVEV-EEDEFDEMDNDMI 317

Query: 633  LQQKYDEVEDKLADISQLQSDQVCSEIKSVHLE---EQIDALSASKKELALVIENLKLDK 689
            +Q+    +     D   L++ ++  E  S  +E   E   AL   + ++   I+ ++ + 
Sbjct: 318  IQEL--NIHKGKIDNMMLEAMELVKEESSTPIEIRGEDSQALEELRVQIKQKIKKIE-EL 374

Query: 690  EQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKM--SAEKISELLAKINHEEQSKI 747
            E+L   +K+ + + E    +++   Q    L   +E+   S +++++ + + N +     
Sbjct: 375  EKLVSVMKEKKEEAEKAEREMRMKCQNESTLMGIIEEFEKSVKELNDRIKEKNKQIDDYE 434

Query: 748  QTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKA---DQLGS 804
            +T        + ++L I+ ++ E+ +  +   +L+E + + E       ++    +Q  +
Sbjct: 435  KTIEENKEDFEAKELIIQQLKDEIIQLTNTEQKLKEQLEIKEKELQEQTKEVKEQNQQQN 494

Query: 805  YLQEKQKAYSEYTIQEDELVNRLAVLMDHDR-VVEKQLLEIEH----ENKELQKKNQILL 859
             +Q+K++   +   + +E +  +   M+ +R  +  ++ E+E+    + +E+ K  +I  
Sbjct: 495  IIQKKEQEIIDIKKKNEETIQLIQKEMEKERNELSIKIKELENIISGKEEEMNKIKEIHD 554

Query: 860  EENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIV 919
             + + +Q     M +      +     +  + E+ +Y+ Q+  LE  +K    E  T  +
Sbjct: 555  YKEKEIQRITEKMNKETEINNKTQQELNKIKEENNEYKNQINTLEIEIKTKEEEKGTTEL 614

Query: 920  QKK---KEIEDL-EIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLN 975
            + K   K I++L E++   +I   I++K+V  ++ +K IE   + + + +E+K  +E  N
Sbjct: 615  ELKENQKSIQELKELKEQERINKEIKEKEV--KELQKIIE---EWKVKEKEWKEQVEE-N 668

Query: 976  MNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNA 1035
               +E ++ N   + + ++K++ +     ++ I++INK N ++K+K +E+  +  +I   
Sbjct: 669  QKEKEESEENKNQMKRIIEKKEEEVKGLNQE-IDKINKENEIMKEKMKELERIKGEIEVL 727

Query: 1036 QVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQL-LDSKQHNEELQILVREQDDQIKE 1094
            ++      ++YE  + +   ++E ++ + ++  K   ++ K+ NEE      E ++ I++
Sbjct: 728  KIKETGDSNEYEKMIEELKKQIEIIKNDNEKERKNNEIEQKKKNEEFNQKEEELNNDIEK 787

Query: 1095 LKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLK--VQEEEEFIQ 1152
             K+        I + +     +T E + +  N ++            L+  + E+ +  +
Sbjct: 788  KKKEIEKLNKQIEELKQKNEENTKENI-EKQNQINQLNLDKEKIMKELESTIMEKNQIEE 846

Query: 1153 ERSVLQE-QSAKLN-------TELQECYTKIIQL-ETLNTELTGHDVVNQEQINQLKSKL 1203
            ER   QE    K+N       T++ E    II+L E  N +    +  NQE   Q+  K 
Sbjct: 847  ERKKEQEINEKKINDIITSKDTKINELNKSIIELKEEWNKKENNLNKSNQELTEQIIQKE 906

Query: 1204 EQLNT---ENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQ 1260
            E +N    EN+NL     E+     + +++   +I E  +Q + +   + +  + E  +Q
Sbjct: 907  EIINVTIKENENLKKVKEEIEKKTETEINELQRKIKENNEQ-INEINKEKENIQKEFEIQ 965

Query: 1261 LSAFESKYEQLLDSVQSSTQEETNKI-VTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQ 1319
            +   ++K +++ + ++   ++E N+I + +E++   +N+L++ ++ L N  E     I +
Sbjct: 966  I---DNKNKEI-NEIKEKNEKEINEIKIQIEEMNKEKNQLENLKKQLENENE-----IIK 1016

Query: 1320 IEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKK 1379
             E  + E E++++ +                + +      K    + I N   E   ++K
Sbjct: 1017 KENKKKEEENKEMGYLIKENEKKIESIRNEINSKERELGTKIKLIEMIKN---EKDIMEK 1073

Query: 1380 SSXXXXXXXXXXXXRVN-DAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVR 1438
                          R+  D E K  ++T  ++ K+ E  +K+ E    L   N E E ++
Sbjct: 1074 DFKKEVDNKNIEIKRLQIDIEKKKNDITLIIQ-KNDEDKKKSIEEKKNL---NQEIEKIK 1129

Query: 1439 QQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITES 1498
             +  + +K  E +  EKE   +       +  N    +++E E     L  E+N KI ++
Sbjct: 1130 SEKNDVQKEKEQILLEKEDLQSDFNKYKTQMENEKLQIKEEHENNITNLQNEINEKINQN 1189

Query: 1499 VSLNKQVAELNKALEE------EVAKTNEMQT-ALENQEIEIVTLNDEITNLQNMVRASS 1551
              +  Q+ +LNK L+E      E  K  E +T   E  + +I   + E+ N++       
Sbjct: 1190 DEIKLQIEQLNKQLDELKQQLVETQKEKEEETKKYEEVKGQIDGAHQEVENIKKETEQQI 1249

Query: 1552 SKIQKHVSFASDTKQGRDEQL 1572
            ++++K       T     E+L
Sbjct: 1250 NQMKKECDEMQKTTFEAKEEL 1270



 Score = 88.6 bits (210), Expect = 1e-15
 Identities = 119/595 (20%), Positives = 259/595 (43%), Gaps = 37/595 (6%)

Query: 217  QMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQ 276
            +  K  E F   E E  ++ ++  K+IE  + +I  L++ N+       E   + ++L  
Sbjct: 766  EQKKKNEEFNQKEEELNNDIEKKKKEIEKLNKQIEELKQKNEENTKENIEKQNQINQLNL 825

Query: 277  ELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNC 336
            + E+              + K  IE   +++ EI EK   +I     +T K   +  LN 
Sbjct: 826  DKEK-----IMKELESTIMEKNQIEEERKKEQEINEKKINDI-----ITSKDTKINELNK 875

Query: 337  QIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQ 396
             I +  +E   K   +   ++ ++    +   +I+     N   K      +  +ET   
Sbjct: 876  SIIELKEEWNKKENNLNKSNQELTEQIIQKEEIINVTIKENENLKKVKEEIEKKTETEIN 935

Query: 397  DTDKKINKNEIAKLEMVIQSLNKDLVDKEYVIS-EKDTXXXXXXXXXXGKDTLIAQLQLE 455
            +  +KI +N     E+   +  K+ + KE+ I  +              K+    ++Q+E
Sbjct: 936  ELQRKIKENNEQINEI---NKEKENIQKEFEIQIDNKNKEINEIKEKNEKEINEIKIQIE 992

Query: 456  HQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQL 515
             + + E   L ++    E+ NEI K + + K+E N E+  + +K+  +K++S   +I   
Sbjct: 993  -EMNKEKNQLENLKKQLENENEIIKKENKKKEEENKEMGYL-IKENEKKIESIRNEINSK 1050

Query: 516  NDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFS-KVSDSNKEIVRLTEELHHLSQKVAEL 574
              E+    K +  +K+   +  K  +K +DN + ++     +I +   ++  + QK  E 
Sbjct: 1051 ERELGTKIKLIEMIKNEKDIMEKDFKKEVDNKNIEIKRLQIDIEKKKNDITLIIQKNDED 1110

Query: 575  E----EEKGNLQLHLVDYDSGRM-IESDVYKKMIEMENLAETRLKAISLLESQKFDLVQE 629
            +    EEK NL   +    S +  ++ +  + ++E E+L     K  + +E++K  + +E
Sbjct: 1111 KKKSIEEKKNLNQEIEKIKSEKNDVQKEKEQILLEKEDLQSDFNKYKTQMENEKLQIKEE 1170

Query: 630  -LHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLD 688
              + +    +E+ +K+      Q+D++  +I+   L +Q+D L     E     E     
Sbjct: 1171 HENNITNLQNEINEKIN-----QNDEIKLQIE--QLNKQLDELKQQLVETQKEKEEETKK 1223

Query: 689  KEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEE--QSK 746
             E++ G I     + E+I  + +  I +     D+++K + E   EL  ++   +  ++K
Sbjct: 1224 YEEVKGQIDGAHQEVENIKKETEQQINQMKKECDEMQKTTFEAKEELRVQVESVKMIETK 1283

Query: 747  IQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQ 801
            + TQ   + K+++R   +E +E  + K K+   R E+     + + + +E + D+
Sbjct: 1284 VSTQKVSNTKLKKR---VEELERTIEKLKNE--RNEKEAFWEKKKMWMIEDEEDK 1333



 Score = 67.3 bits (157), Expect = 3e-09
 Identities = 127/667 (19%), Positives = 271/667 (40%), Gaps = 62/667 (9%)

Query: 87   VPGISESLANTLKQKEILMEKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTH 146
            V G+++ +    K+ EI+ EK+K+ + +  +    +++               +L     
Sbjct: 693  VKGLNQEIDKINKENEIMKEKMKELERI--KGEIEVLKIKETGDSNEYEKMIEELKKQIE 750

Query: 147  LSNTIKEKDNALSVLQVKMKIMETTILDLQ------------EKINEKDQIIEAKNKATT 194
            +     EK+   + ++ K K  E    + +            EK+N++ + ++ KN+  T
Sbjct: 751  IIKNDNEKERKNNEIEQKKKNEEFNQKEEELNNDIEKKKKEIEKLNKQIEELKQKNEENT 810

Query: 195  XXXXXXXXXXXXXXXXXEDTKQQM--TKMQENFIAMEAEWKDE-KQRLLKD-IESKDVRI 250
                             E   +++  T M++N I  E + + E  ++ + D I SKD +I
Sbjct: 811  KENIEKQNQINQLNLDKEKIMKELESTIMEKNQIEEERKKEQEINEKKINDIITSKDTKI 870

Query: 251  SSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEI 310
            +   E NK +   + E + + + L +  ++                K++ E   + K EI
Sbjct: 871  N---ELNKSIIELKEEWNKKENNLNKSNQELTEQIIQKEEIINVTIKEN-ENLKKVKEEI 926

Query: 311  EEKGSLEIANM-TELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKK--GS 367
            E+K   EI  +  ++ +  E +  +N +     KE E ++     E   +   ++K    
Sbjct: 927  EKKTETEINELQRKIKENNEQINEINKEKENIQKEFEIQIDNKNKEINEIKEKNEKEINE 986

Query: 368  PLISRKSGRNTASKMKSPWSQLSSET--LNQDTDKKINKNE-----IAKLEMVIQSLNKD 420
              I  +      +++++   QL +E   + ++  KK  +N+     I + E  I+S+  +
Sbjct: 987  IKIQIEEMNKEKNQLENLKKQLENENEIIKKENKKKEEENKEMGYLIKENEKKIESIRNE 1046

Query: 421  LVDK-----------EYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVG 469
            +  K           E + +EKD            K+  I +LQ++ ++     +LI + 
Sbjct: 1047 INSKERELGTKIKLIEMIKNEKDIMEKDFKKEVDNKNIEIKRLQIDIEKKKNDITLI-IQ 1105

Query: 470  TNTEDVNEIAKVQEQLKQE---LNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNM 526
             N ED  +  + ++ L QE   +  E  DV  K+  + L   E+  +  N          
Sbjct: 1106 KNDEDKKKSIEEKKNLNQEIEKIKSEKNDVQ-KEKEQILLEKEDLQSDFNKYKTQMENEK 1164

Query: 527  IKVKSNHKLKLKQMQKTIDNFSKVSDSNK-EIVRLTEELHHLSQKVAELEEEKGNLQLHL 585
            +++K  H+  +  +Q  I+     +D  K +I +L ++L  L Q++ E ++EK   +   
Sbjct: 1165 LQIKEEHENNITNLQNEINEKINQNDEIKLQIEQLNKQLDELKQQLVETQKEKEE-ETKK 1223

Query: 586  VDYDSGRM--IESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDK 643
             +   G++     +V     E E       K    ++   F+  +EL +  +    +E K
Sbjct: 1224 YEEVKGQIDGAHQEVENIKKETEQQINQMKKECDEMQKTTFEAKEELRVQVESVKMIETK 1283

Query: 644  LADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDK 703
            ++   ++ + ++   ++   LE  I+ L   + E     E  K+        I+D E DK
Sbjct: 1284 VS-TQKVSNTKLKKRVE--ELERTIEKLKNERNEKEAFWEKKKM------WMIED-EEDK 1333

Query: 704  EDIMNKL 710
            + + N L
Sbjct: 1334 KVLFNSL 1340


>UniRef50_A2DGH5 Cluster: Viral A-type inclusion protein, putative;
            n=1; Trichomonas vaginalis G3|Rep: Viral A-type inclusion
            protein, putative - Trichomonas vaginalis G3
          Length = 1579

 Score =  149 bits (360), Expect = 8e-34
 Identities = 255/1344 (18%), Positives = 555/1344 (41%), Gaps = 111/1344 (8%)

Query: 296  AKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTE 355
            A + I     E  ++EE+  +E+  ++ L K+  +++ LN Q+  + + ++       T+
Sbjct: 117  ATEDIAVLTAENKQLEEQ--VELYRLSSL-KQQSIIDELNSQL-SSPQVIDKPQRFADTK 172

Query: 356  SKAVSSPSKKG-SPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVI 414
               +   +KK  S +IS +  +  ++   S     + E   Q TD   N++E     + I
Sbjct: 173  IHLLQEKNKKLLSTVISLRKQQQISNVELSTQKSANRELTQQLTDALTNEDEDQDTIVHI 232

Query: 415  QSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTED 474
            + ++     K+ V  E +            +   + Q  LE  +  +        +NTE+
Sbjct: 233  EDMSSYPEVKKLV--EMNARKAKRIESLKSEINFMKQTILEQSEKEKTLIDFIESSNTEN 290

Query: 475  VNEIAKVQEQLKQELNDEIKDVNVK----DLIEKLKSAEEQITQLNDE--IDAANKNMIK 528
              ++ ++ ++L    N +I  V       +L + L   + Q+T+L  +  I+   K+ +K
Sbjct: 291  QKKLTEMNQRLSDFQNSKISQVTDDSQNTELRKSLDEMKSQLTELRKKSLIEEQQKSQLK 350

Query: 529  VK--------SNHKLKLKQMQKTI--DNFSKVSDSNKEIVRLTEELHHLSQKV----AEL 574
             +        S+ K KLK    T    N+S      +E+ + T+E+  +   +    + L
Sbjct: 351  TELEKVQSENSDLKEKLKFSSDTSFDSNYSMDPIFEQELQQKTKEISQMKVAINSLTSML 410

Query: 575  EEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQ 634
             E + NLQ  + + ++   I     K+  +  N     +KAI   + + F+ ++E   +Q
Sbjct: 411  SENEQNLQSQISEKENELQIAQQNIKRCQDELN----SMKAIQEEQGKSFNRIKEN--VQ 464

Query: 635  QKYDEVEDKLADISQLQSDQVCSEIKSV---------HLEEQIDALSASKKELALVIENL 685
               D+V+   +  S   +D + S +K V           ++ +  L    ++L   ++  
Sbjct: 465  VLLDDVQTSFSFASLKVTDDMDS-LKDVSKFICTNYNRSKDMVSQLQKENEDLKKELKQS 523

Query: 686  KLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQS 745
             L  ++L  T+ DL +  E    KLQN + +   + ++  K   +K    ++ IN  E  
Sbjct: 524  NLKNKELSLTLNDLRSSTE---MKLQNTMSQQQ-MNEERMKEELQKSQNQISTIN--EMF 577

Query: 746  KIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSY 805
            K Q     +  +    L I+  E E    K++I  L + ++  + R+       + L + 
Sbjct: 578  K-QKSIEYEKDLATSHLTIDQFEEEKVNMKTKIDDLLDQLSAFQSRQTDFTSSINSLETT 636

Query: 806  LQEKQKAYSEYTIQEDELVNRLAVLMDH--DRV--VEKQLLEIEHENKELQKKNQILLEE 861
             + K+K+ S+   Q ++  ++L +  +   +RV  +E  +L++ +ENK+++ K Q L+ E
Sbjct: 637  YKNKEKSLSDTISQLNDDKSKLKLKEEQLTNRVNSMESAMLDLRNENKKIENKKQKLIVE 696

Query: 862  NQNLQISLSDM-QQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQ----- 915
            N  L+ +L +   ++   L EK  +    +  +++ + Q+++L+  +K    + +     
Sbjct: 697  NNELKTALEEFTNENKTTLAEKDQKYYKLKETNSEMENQIKELKKEVKEQRKQFEDLKNQ 756

Query: 916  -TLIVQKKKE-IEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIEN 973
             TL +Q K E I  L ++     E+ +   K  ++K  +N+E   Q+  Q    +   E 
Sbjct: 757  STLSLQTKAEKINKLRLKLKQLQEAFVNLTKEKDQKERENVELQLQITGQSDTVRR-AEE 815

Query: 974  LNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKIN 1033
             +  +    +    +     +K Q    +Y + ++  + K    +++  ++++   +K  
Sbjct: 816  QSQKMTAAKEAGDYVFKSLTKKYQDLQKEYAD-HLQFVEKSKEDIEEM-KKVVDDKEKER 873

Query: 1034 NAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIK 1093
            +  V  M+      SKL     +  ++E+E  ++S  L  + ++N  LQI  ++  ++IK
Sbjct: 874  SDAVDQMNSTI---SKLENLQNEKNDIEKENSQLSSDLETANKNNTNLQIERKQNLEKIK 930

Query: 1094 EL--------KETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLK-- 1143
            EL         +  +  + N   ++  ++ S  E + +D + +              K  
Sbjct: 931  ELTDNNQELKSQISVLQKQNHELSQNTVLLSVYEKLKNDKDELQKSFNFINDELHTTKSC 990

Query: 1144 -VQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHD--VVN--QEQINQ 1198
               E++E+   +  + ++ A L + +++   +I +++  N      D   +N  Q+Q++ 
Sbjct: 991  YEMEDKEYTDYKDQMTKKVASLTSTIEDLNKEIAKIKDENDRAAQQDTQTINKLQDQVDS 1050

Query: 1199 LKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELR 1258
            L+ KLE    E   +     E+R     +VD       +     L Q   +  K   EL+
Sbjct: 1051 LRGKLETQTAEYSKIDEETKEIRKKSRESVDN-----IKAKNNELTQAIENKGKLIDELK 1105

Query: 1259 VQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVIN 1318
             ++   E   + ++ +  +   +   KI   +Q+ + Q+  Q+K +        Y   I 
Sbjct: 1106 NKIKELEDDKKDIMSNYDNLNAQ---KIEVEKQLNTTQSTQQEKFDDFTRKLSSYKQKI- 1161

Query: 1319 QIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTE--NQSYKQMQEQSILNINE---E 1373
                   E+E +K                    LR       Y ++Q++  L   E   E
Sbjct: 1162 ------KEMEADKATSERIIRENGLRIDELKSQLRNSVPKDDYNKLQKKIDLLKKEKLLE 1215

Query: 1374 NAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDE 1433
            +  L+K++            +    E    +   QL+    +  +        +   N E
Sbjct: 1216 STVLQKTAFANEVNAEKLKDKFTRKEKDYQDQIEQLKQDRDKKAEAAKNLASQVKSLNQE 1275

Query: 1434 FENVRQQLVEYEKRIED--LTYEKESELAILRLKMHENANHYETMQ-KESEIERV-KLIE 1489
                 +  V    + E   ++ E ++++  L L   +  N  + +Q KE EIE + K IE
Sbjct: 1276 LVKATENKVPMCPKAEKDAISMELKAKVEELALSETKLKNKDQIIQMKEKEIEELNKNIE 1335

Query: 1490 ELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEI----TNLQN 1545
            +L  +I E  S + Q+ ELN+++    A        + +    I ++N+++     +L+ 
Sbjct: 1336 KLKDQIEEIKSNDDQIQELNESISNLAADNKSKDNEIASLTTTIRSMNEKLLSKTKDLEQ 1395

Query: 1546 MVRASSSKIQKHVSFASDTKQGRD 1569
            M    ++K  K +   +  K  +D
Sbjct: 1396 MKSDMNNKNPKVIQLDNINKIAKD 1419



 Score =  122 bits (294), Expect = 8e-26
 Identities = 226/1201 (18%), Positives = 493/1201 (41%), Gaps = 107/1201 (8%)

Query: 472  TEDVNEIAKVQEQLKQELN-DEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVK 530
            TED+  +    +QL++++    +  +  + +I++L S +    Q+ D+        I + 
Sbjct: 118  TEDIAVLTAENKQLEEQVELYRLSSLKQQSIIDELNS-QLSSPQVIDKPQRFADTKIHLL 176

Query: 531  SNHKLKLKQMQKTIDNFSKVSD-SNKEIVRLTEELHHLSQKVAEL---EEEKGNLQLHLV 586
                 K K++  T+ +  K    SN E+         L+Q++ +    E+E  +  +H+ 
Sbjct: 177  QE---KNKKLLSTVISLRKQQQISNVELSTQKSANRELTQQLTDALTNEDEDQDTIVHIE 233

Query: 587  DYDS----GRMIESDVYK-KMIEMENLAETRLKAISLLESQK----FDLVQELHIL-QQK 636
            D  S     +++E +  K K IE        +K   L +S+K     D ++  +   Q+K
Sbjct: 234  DMSSYPEVKKLVEMNARKAKRIESLKSEINFMKQTILEQSEKEKTLIDFIESSNTENQKK 293

Query: 637  YDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTI 696
              E+  +L+D    +  QV  + ++  L + +D + +   EL       +  K QL   +
Sbjct: 294  LTEMNQRLSDFQNSKISQVTDDSQNTELRKSLDEMKSQLTELRKKSLIEEQQKSQLKTEL 353

Query: 697  KDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAK 756
            + ++++  D+  KL+     + D    ++ +  +++ +   +I+  + +       +   
Sbjct: 354  EKVQSENSDLKEKLKFSSDTSFDSNYSMDPIFEQELQQKTKEISQMKVAINSLTSMLSEN 413

Query: 757  IQERDLYIENIESELSKYKSRICRLEESI----AVMEDRRYSLERKADQLGSYLQEKQKA 812
             Q     I   E+EL   +  I R ++ +    A+ E++  S  R  + +   L + Q +
Sbjct: 414  EQNLQSQISEKENELQIAQQNIKRCQDELNSMKAIQEEQGKSFNRIKENVQVLLDDVQTS 473

Query: 813  YS----EYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQIS 868
            +S    + T   D L +    +  +    +  + +++ EN++L+K+ +    +N+ L ++
Sbjct: 474  FSFASLKVTDDMDSLKDVSKFICTNYNRSKDMVSQLQKENEDLKKELKQSNLKNKELSLT 533

Query: 869  LSDMQQH-----YNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKK 923
            L+D++        N + ++    +  + E  K Q Q+  +    K+ + E++  +     
Sbjct: 534  LNDLRSSTEMKLQNTMSQQQMNEERMKEELQKSQNQISTINEMFKQKSIEYEKDLATSHL 593

Query: 924  EIEDLEIEFNTQIESAIRD-KKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELN 982
             I+  E E    +++ I D    L+    +  ++ + + +    YKN  ++L+  + +LN
Sbjct: 594  TIDQFE-EEKVNMKTKIDDLLDQLSAFQSRQTDFTSSINSLETTYKNKEKSLSDTISQLN 652

Query: 983  KMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSM 1042
                +L  K  ++Q T   +  E  + ++   N  ++ K +++I  N ++  A   + + 
Sbjct: 653  DDKSKL--KLKEEQLTNRVNSMESAMLDLRNENKKIENKKQKLIVENNELKTALEEFTNE 710

Query: 1043 VSDYESKLAQFTTKLENMEEEMQRVSKQL-LDSKQHNEELQILVREQDDQIKELKETKLT 1101
                 ++  Q   KL+    EM+   K+L  + K+  ++ + L  +    ++   E    
Sbjct: 711  NKTTLAEKDQKYYKLKETNSEMENQIKELKKEVKEQRKQFEDLKNQSTLSLQTKAEKINK 770

Query: 1102 FEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFI----QERSVL 1157
              + + + +   ++ T E    +  NV+             + +E+ + +    +    +
Sbjct: 771  LRLKLKQLQEAFVNLTKEKDQKERENVELQLQITGQSDTVRRAEEQSQKMTAAKEAGDYV 830

Query: 1158 QEQSAKLNTELQECYTKIIQ--------LETLNTELTGHDVVNQEQINQLK---SKLEQL 1206
             +   K   +LQ+ Y   +Q        +E +   +   +    + ++Q+    SKLE L
Sbjct: 831  FKSLTKKYQDLQKEYADHLQFVEKSKEDIEEMKKVVDDKEKERSDAVDQMNSTISKLENL 890

Query: 1207 NTENDNLLSTVAELRSSISSA----------VDQRGFEIAELW--KQHLAQREADFQKTE 1254
              E +++    ++L S + +A            Q   +I EL    Q L  + +  QK  
Sbjct: 891  QNEKNDIEKENSQLSSDLETANKNNTNLQIERKQNLEKIKELTDNNQELKSQISVLQKQN 950

Query: 1255 HELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKE--EHLRNLQEK 1312
            HEL  Q +   S YE+L +  +   Q+  N I      T    +++DKE  ++   + +K
Sbjct: 951  HELS-QNTVLLSVYEKLKND-KDELQKSFNFINDELHTTKSCYEMEDKEYTDYKDQMTKK 1008

Query: 1313 YADVINQIEILRSE---IEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILN 1369
             A + + IE L  E   I+DE                     LR + ++  Q  E S   
Sbjct: 1009 VASLTSTIEDLNKEIAKIKDENDRAAQQDTQTINKLQDQVDSLRGKLET--QTAEYS--K 1064

Query: 1370 INEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKD---SEIYQKTHEYTIT 1426
            I+EE  +++K S             V++ +AK  ELT  +E K     E+  K  E    
Sbjct: 1065 IDEETKEIRKKSRES----------VDNIKAKNNELTQAIENKGKLIDELKNKIKELEDD 1114

Query: 1427 LTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKE-SEIERV 1485
                   ++N+  Q +E EK++      ++ +      K+       + M+ + +  ER+
Sbjct: 1115 KKDIMSNYDNLNAQKIEVEKQLNTTQSTQQEKFDDFTRKLSSYKQKIKEMEADKATSERI 1174

Query: 1486 -----KLIEELNVKITESV---SLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLN 1537
                   I+EL  ++  SV     NK   +++   +E++ ++  +Q      E+    L 
Sbjct: 1175 IRENGLRIDELKSQLRNSVPKDDYNKLQKKIDLLKKEKLLESTVLQKTAFANEVNAEKLK 1234

Query: 1538 DEIT--------NLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAEL 1589
            D+ T         ++ + +    K +   + AS  K    E +  T NK  +   P+AE 
Sbjct: 1235 DKFTRKEKDYQDQIEQLKQDRDKKAEAAKNLASQVKSLNQELVKATENK--VPMCPKAEK 1292

Query: 1590 D 1590
            D
Sbjct: 1293 D 1293



 Score =  121 bits (291), Expect = 2e-25
 Identities = 186/912 (20%), Positives = 383/912 (41%), Gaps = 79/912 (8%)

Query: 148  SNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXX 207
            S+T  +  N +S  Q+  + M+  +   Q +I+  +++ + K+                 
Sbjct: 539  SSTEMKLQNTMSQQQMNEERMKEELQKSQNQISTINEMFKQKS----IEYEKDLATSHLT 594

Query: 208  XXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEI 267
                E+ K  M    ++ +   + ++  +      I S +    + E   K L     ++
Sbjct: 595  IDQFEEEKVNMKTKIDDLLDQLSAFQSRQTDFTSSINSLETTYKNKE---KSLSDTISQL 651

Query: 268  SLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTK- 326
            + + SKL  + EQ              L  ++ +   +++  I E   L+ A + E T  
Sbjct: 652  NDDKSKLKLKEEQLTNRVNSMESAMLDLRNENKKIENKKQKLIVENNELKTA-LEEFTNE 710

Query: 327  -KIELLE--HLNCQIRQTNKELENKLATMGTESKAVSSPSK--KGSPLISRKSGRNTASK 381
             K  L E      ++++TN E+EN++  +  E K      +  K    +S ++     +K
Sbjct: 711  NKTTLAEKDQKYYKLKETNSEMENQIKELKKEVKEQRKQFEDLKNQSTLSLQTKAEKINK 770

Query: 382  MKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXX 441
            ++    QL    +N   +K   + E  +L++ I     D V +    S+K T        
Sbjct: 771  LRLKLKQLQEAFVNLTKEKDQKERENVELQLQITG-QSDTVRRAEEQSQKMTAAKEAGDY 829

Query: 442  XXGKDTLIAQ-LQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVN--- 497
                 T   Q LQ E+  H++      V  + ED+ E+ KV +  ++E +D +  +N   
Sbjct: 830  VFKSLTKKYQDLQKEYADHLQ-----FVEKSKEDIEEMKKVVDDKEKERSDAVDQMNSTI 884

Query: 498  --VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNK 555
              +++L  +    E++ +QL+ +++ ANKN   ++   K  L+++++  DN  ++     
Sbjct: 885  SKLENLQNEKNDIEKENSQLSSDLETANKNNTNLQIERKQNLEKIKELTDNNQELKS--- 941

Query: 556  EIVRLTEELHHLSQKVA------ELEEEKGNLQ---------LHLVD--YDSGRMIESD- 597
            +I  L ++ H LSQ         +L+ +K  LQ         LH     Y+      +D 
Sbjct: 942  QISVLQKQNHELSQNTVLLSVYEKLKNDKDELQKSFNFINDELHTTKSCYEMEDKEYTDY 1001

Query: 598  ---VYKKMIEMENLAETRLKAISLLESQKFDLVQE----LHILQQKYDEVEDKLADISQL 650
               + KK+  + +  E   K I+ ++ +     Q+    ++ LQ + D +  KL +    
Sbjct: 1002 KDQMTKKVASLTSTIEDLNKEIAKIKDENDRAAQQDTQTINKLQDQVDSLRGKL-ETQTA 1060

Query: 651  QSDQVCSEIKSVHLE--EQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMN 708
            +  ++  E K +  +  E +D + A   EL   IEN     ++L   IK+LE+DK+DIM+
Sbjct: 1061 EYSKIDEETKEIRKKSRESVDNIKAKNNELTQAIENKGKLIDELKNKIKELEDDKKDIMS 1120

Query: 709  KLQNYIQENMDLTDKL---EKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIE 765
               N   + +++  +L   +    EK  +   K++  +Q KI+ +   D    ER   I 
Sbjct: 1121 NYDNLNAQKIEVEKQLNTTQSTQQEKFDDFTRKLSSYKQ-KIK-EMEADKATSER--IIR 1176

Query: 766  NIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVN 825
                 + + KS++       +V +D    L++K D     L +K+K      +Q+    N
Sbjct: 1177 ENGLRIDELKSQLRN-----SVPKDDYNKLQKKID-----LLKKEKLLESTVLQKTAFAN 1226

Query: 826  RLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQH-YNALVEKAN 884
             +      D+   K+  + + + ++L++      E  +NL   +  + Q    A   K  
Sbjct: 1227 EVNAEKLKDKFTRKE-KDYQDQIEQLKQDRDKKAEAAKNLASQVKSLNQELVKATENKVP 1285

Query: 885  RTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQ-KKKEIEDLEIEFNTQIESAIRDK 943
                AE ++   + + +  E  L     +++  I+Q K+KEIE+L      +++  I + 
Sbjct: 1286 MCPKAEKDAISMELKAKVEELALSETKLKNKDQIIQMKEKEIEELNKNIE-KLKDQIEEI 1344

Query: 944  KVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELN-KMNLELIDKHVQKQQTQSPD 1002
            K  +++ ++  E ++ L A  +   N I +L   +  +N K+  +  D    K    + +
Sbjct: 1345 KSNDDQIQELNESISNLAADNKSKDNEIASLTTTIRSMNEKLLSKTKDLEQMKSDMNNKN 1404

Query: 1003 YTEQYINEINKL 1014
                 ++ INK+
Sbjct: 1405 PKVIQLDNINKI 1416



 Score = 90.6 bits (215), Expect = 3e-16
 Identities = 168/916 (18%), Positives = 370/916 (40%), Gaps = 64/916 (6%)

Query: 665  EEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQEN-MDLTDK 723
            E +I      K+  +L  EN KL K +L  +   ++ +KE+  N+ QN ++ N +D+ +K
Sbjct: 56   EMRITQAKMIKQIESLNKENRKL-KLELDCSQNQIQENKEEHNNE-QNTLKNNILDMKNK 113

Query: 724  LEKMSAEKISELLAKINH-EEQSKIQTQFGIDAK--IQERDLYIEN---IESELSKYKSR 777
            L + + E I+ L A+    EEQ ++     +  +  I E +  + +   I+       ++
Sbjct: 114  LRR-ATEDIAVLTAENKQLEEQVELYRLSSLKQQSIIDELNSQLSSPQVIDKPQRFADTK 172

Query: 778  ICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQE--DELVNRLAVLMDHDR 835
            I  L+E    +     SL RK  Q+ +     QK+ +    Q+  D L N      D D 
Sbjct: 173  IHLLQEKNKKLLSTVISL-RKQQQISNVELSTQKSANRELTQQLTDALTNEDE---DQDT 228

Query: 836  VVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRT-DLAESEST 894
            +V  + +    E K+L + N    +  ++L+  ++ M+Q      EK     D  ES +T
Sbjct: 229  IVHIEDMSSYPEVKKLVEMNARKAKRIESLKSEINFMKQTILEQSEKEKTLIDFIESSNT 288

Query: 895  KYQTQLRDLESNLKRITHEHQTLIVQKKK--EIEDLEIEFNTQIESAIRDKKVLNEKYEK 952
            + Q +L ++   L    +   + +    +  E+     E  +Q+ + +R K ++ E+ + 
Sbjct: 289  ENQKKLTEMNQRLSDFQNSKISQVTDDSQNTELRKSLDEMKSQL-TELRKKSLIEEQQKS 347

Query: 953  NIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEIN 1012
             ++  T+LE    E  +  E L  + +     N  +     Q+ Q ++ + ++  +  IN
Sbjct: 348  QLK--TELEKVQSENSDLKEKLKFSSDTSFDSNYSMDPIFEQELQQKTKEISQMKV-AIN 404

Query: 1013 KLNALLKQKDEEIIA-LNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQ- 1070
             L ++L + ++ + + +++K N  Q++  + +   + +L       E   +   R+ +  
Sbjct: 405  SLTSMLSENEQNLQSQISEKENELQIAQQN-IKRCQDELNSMKAIQEEQGKSFNRIKENV 463

Query: 1071 --LLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMI--ISSTIEPMSDDAN 1126
              LLD  Q +     L  +  D +  LK+       N  +++ M+  +    E +  +  
Sbjct: 464  QVLLDDVQTSFSFASL--KVTDDMDSLKDVSKFICTNYNRSKDMVSQLQKENEDLKKELK 521

Query: 1127 NVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELT 1186
              +            L+   E +     S  Q    ++  ELQ+      Q+ T+N    
Sbjct: 522  QSNLKNKELSLTLNDLRSSTEMKLQNTMSQQQMNEERMKEELQKSQN---QISTINEMFK 578

Query: 1187 GHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQR 1246
               +  ++ +      ++Q   E  N+ + + +L   +S+                   R
Sbjct: 579  QKSIEYEKDLATSHLTIDQFEEEKVNMKTKIDDLLDQLSA----------------FQSR 622

Query: 1247 EADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHL 1306
            + DF  + + L    + +++K + L D++     +++   +  EQ+T+  N ++     L
Sbjct: 623  QTDFTSSINSLE---TTYKNKEKSLSDTISQLNDDKSKLKLKEEQLTNRVNSMESAMLDL 679

Query: 1307 RNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQS 1366
            RN  +K  +   ++ +  +E++     F                 L+  N   +   ++ 
Sbjct: 680  RNENKKIENKKQKLIVENNELKTALEEFTNENKTTLAEKDQKYYKLKETNSEMENQIKEL 739

Query: 1367 ILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTH---EY 1423
               + E+  Q +               ++N    K+ +L         E  QK     E 
Sbjct: 740  KKEVKEQRKQFEDLKNQSTLSLQTKAEKINKLRLKLKQLQEAFVNLTKEKDQKERENVEL 799

Query: 1424 TITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESE-I 1482
             + +T ++D      +Q  +     E   Y  +S     +    E A+H + ++K  E I
Sbjct: 800  QLQITGQSDTVRRAEEQSQKMTAAKEAGDYVFKSLTKKYQDLQKEYADHLQFVEKSKEDI 859

Query: 1483 ERV-KLIEELNVKITESV-SLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEI 1540
            E + K++++   + +++V  +N  +++L     E+    N+++        ++ T N   
Sbjct: 860  EEMKKVVDDKEKERSDAVDQMNSTISKLENLQNEK----NDIEKENSQLSSDLETANKNN 915

Query: 1541 TNLQNMVRASSSKIQK 1556
            TNLQ   + +  KI++
Sbjct: 916  TNLQIERKQNLEKIKE 931



 Score = 76.2 bits (179), Expect = 7e-12
 Identities = 141/720 (19%), Positives = 296/720 (41%), Gaps = 73/720 (10%)

Query: 923  KEIEDLEIEFNT-QIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEEL 981
            K+IE L  E    ++E      ++   K E N E  T L+  + + KN +     ++  L
Sbjct: 66   KQIESLNKENRKLKLELDCSQNQIQENKEEHNNEQNT-LKNNILDMKNKLRRATEDIAVL 124

Query: 982  NKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMS 1041
               N +L ++ V+  +  S    +  I+E+N   +  +  D+     + KI+  Q     
Sbjct: 125  TAENKQL-EEQVELYRLSSLKQ-QSIIDELNSQLSSPQVIDKPQRFADTKIHLLQEKNKK 182

Query: 1042 MVSDYES--KLAQFTT-KLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKET 1098
            ++S   S  K  Q +  +L   +   + +++QL D+  + +E Q  +   +D +    E 
Sbjct: 183  LLSTVISLRKQQQISNVELSTQKSANRELTQQLTDALTNEDEDQDTIVHIED-MSSYPEV 241

Query: 1099 KLTFEMNIPKTEGM--------IISSTIEPMSDDANN-VDXXXXXXXXXXXXL-KVQEEE 1148
            K   EMN  K + +         +  TI   S+     +D            L ++ +  
Sbjct: 242  KKLVEMNARKAKRIESLKSEINFMKQTILEQSEKEKTLIDFIESSNTENQKKLTEMNQRL 301

Query: 1149 EFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNT 1208
               Q   + Q      NTEL++    + ++++  TEL    ++ ++Q +QLK++LE++ +
Sbjct: 302  SDFQNSKISQVTDDSQNTELRK---SLDEMKSQLTELRKKSLIEEQQKSQLKTELEKVQS 358

Query: 1209 ENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKY 1268
            EN +L     +L+ S  ++ D   + +  +++Q L Q+  +      +++V +++  S  
Sbjct: 359  ENSDLKE---KLKFSSDTSFDSN-YSMDPIFEQELQQKTKEIS----QMKVAINSLTSML 410

Query: 1269 EQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQI-EILRSEI 1327
             +   ++QS   E+ N++   +Q      + QD+   ++ +QE+     N+I E ++  +
Sbjct: 411  SENEQNLQSQISEKENELQIAQQNIK---RCQDELNSMKAIQEEQGKSFNRIKENVQVLL 467

Query: 1328 EDEKVAFXXXXXXXXXXXXXXX-----------------XDLRTENQSYKQMQEQSILNI 1370
            +D + +F                                  L+ EN+  K+  +QS L  
Sbjct: 468  DDVQTSFSFASLKVTDDMDSLKDVSKFICTNYNRSKDMVSQLQKENEDLKKELKQSNLKN 527

Query: 1371 NEENAQLK--KSSXXXXXXXXXXXXRVNDAEAK--VLELTHQLELKDSEIYQKTHEYTIT 1426
             E +  L   +SS            ++N+   K  + +  +Q+   +    QK+ EY   
Sbjct: 528  KELSLTLNDLRSSTEMKLQNTMSQQQMNEERMKEELQKSQNQISTINEMFKQKSIEYEKD 587

Query: 1427 LTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVK 1486
            L   +   +   ++ V  + +I+DL  ++ S     +     + N  ET  K  E     
Sbjct: 588  LATSHLTIDQFEEEKVNMKTKIDDLL-DQLSAFQSRQTDFTSSINSLETTYKNKEKSLSD 646

Query: 1487 LIEELN-----VKITESVSLNK---------QVAELNKALEEE----VAKTNEMQTALEN 1528
             I +LN     +K+ E    N+          +   NK +E +    + + NE++TALE 
Sbjct: 647  TISQLNDDKSKLKLKEEQLTNRVNSMESAMLDLRNENKKIENKKQKLIVENNELKTALEE 706

Query: 1529 QEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAE 1588
               E  T   E       ++ ++S+++  +       + + +Q ++  N+  L    +AE
Sbjct: 707  FTNENKTTLAEKDQKYYKLKETNSEMENQIKELKKEVKEQRKQFEDLKNQSTLSLQTKAE 766



 Score = 38.3 bits (85), Expect = 1.7
 Identities = 50/289 (17%), Positives = 113/289 (39%), Gaps = 11/289 (3%)

Query: 220  KMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELE 279
            K+++ F   E +++D+ ++L +D + K     +L    K L     + +     +  + E
Sbjct: 1232 KLKDKFTRKEKDYQDQIEQLKQDRDKKAEAAKNLASQVKSLNQELVKATENKVPMCPKAE 1291

Query: 280  QXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEI-ANMTELTKKIELLEHLNCQI 338
            +                 ++   + ++  +++EK   E+  N+ +L  +IE ++  + QI
Sbjct: 1292 KDAISMELKAKVEELALSETKLKNKDQIIQMKEKEIEELNKNIEKLKDQIEEIKSNDDQI 1351

Query: 339  RQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDT 398
            ++ N+ + N  A   ++   ++S +        R       SK K    Q+ S+ +N   
Sbjct: 1352 QELNESISNLAADNKSKDNEIASLTTT-----IRSMNEKLLSKTKD-LEQMKSD-MNNKN 1404

Query: 399  DKKINKNEIAKLEM-VIQSLNKDLVDKEYVISEKDTXXXXXXXXXX--GKDTLIAQLQLE 455
             K I  + I K+   ++  +N     K+  +    T            G  +        
Sbjct: 1405 PKVIQLDNINKIAKDLLNIINSPQFAKQQALQRLSTLQDSISTIFTILGLPSSNIMPPAR 1464

Query: 456  HQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEK 504
               H +GP     G  + +  E  K+ E + +E  +  K+V   D +++
Sbjct: 1465 ALSHQQGPIFYIPGDKSLETKEERKIAELIIREFPELGKEVTDSDSLDR 1513


>UniRef50_UPI0000D565C6 Cluster: PREDICTED: similar to CG3493-PA; n=1;
            Tribolium castaneum|Rep: PREDICTED: similar to CG3493-PA
            - Tribolium castaneum
          Length = 1398

 Score =  148 bits (359), Expect = 1e-33
 Identities = 248/1219 (20%), Positives = 527/1219 (43%), Gaps = 105/1219 (8%)

Query: 147  LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINE--KDQIIEAKNKATTXXXXXXXXXX 204
            L + I EK   +  LQ K+++++T   +  + +N+   D  +E +N              
Sbjct: 189  LRDEIDEKQFKIESLQTKIELLQTPETENPDTLNKYLTDARVEIEN--LNQRIQEMKANS 246

Query: 205  XXXXXXXEDTKQQMTKMQENFIAMEAEWKDE--------KQRLLKDIESKDVRISSLEEA 256
                   ++ K ++T +++  IA+ +E + E        K  L  ++ SKD  IS+L+++
Sbjct: 247  IIFQTKEQEYKAKITNLEKE-IALFSEREKENNLSLAQNKMELHNELLSKDAEISNLKKS 305

Query: 257  NKLLEAA--RFE-ISLEHSKLAQELEQXXXXXXXXXXXXXXLA--KQSIEPSCEEKTEIE 311
             + L     +FE +  +++KL ++LE               +   ++  E +   K EI+
Sbjct: 306  LEALTGGTGKFENLQTQNTKLIEKLEALTQKCNNYENKLLKMEQLRRENEENSRLKKEIQ 365

Query: 312  E-KGSLEIANMTELTKKIELLEHLNCQIRQT-NKELENKLATMGTE-SKAVSSPSKKGSP 368
            + +G LE   + E  KK  LL  L  +IR+   KE E K   + ++  K +   S   S 
Sbjct: 366  DIQGQLE--GVREEAKK-SLLS-LETKIREKLAKEFEEKEERLRSDFRKKIEEVSSSSSN 421

Query: 369  LISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAK--LEMVIQS--LNKDL--V 422
              +         K++    Q++   L Q T K    +++ +  LE++ +S  L   +  +
Sbjct: 422  EFNLLEMEEEIRKLR----QVNDGILEQLTSKTTKYDDLERNHLELIEESGRLRSQIGGL 477

Query: 423  DKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGP--SLIHVGTN-TEDVNEIA 479
            +KE    +               +  + +  +E  + +E     L+    N  ED+ E  
Sbjct: 478  EKELATLQNTNQAANLKLGHLEANARVLERTVEEYKRLEAERDDLLQEKKNFMEDLEEER 537

Query: 480  KVQEQLKQELNDEIKDVNVK--DLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKL 537
            ++ E+L  E+ ++++D  VK  DL   L+   +   +LN E++        VK + + K 
Sbjct: 538  RINERLNLEV-EQLRDEMVKKSDLEHSLEEERKVTQKLNTELE-------NVKCHIEEKK 589

Query: 538  KQMQKTIDNFSKVSDSNKEIVRLTEE---LHHLSQKVAELEEEKGNLQLHLVDYDSGRMI 594
            K ++ T+D      +  K + +L E    + HL      L EE  +L+L   +       
Sbjct: 590  KDLELTLDE-----EKGKLLQKLEESSVNMKHLEDTGLALSEELNSLKLKNEELAKLAEE 644

Query: 595  ESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQ-LQSD 653
               + KK+ E E     + + I  LE +       L   ++K  E+ ++   +   L+ +
Sbjct: 645  RDTLLKKLTESEETNSLQTRKIQNLEEEMAKKAVSLEEAKRKILELGEQNNSLGHNLEEE 704

Query: 654  QVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNY 713
            +  ++     LE     +   KK L      L LD+E+     K L+N +E   +K   +
Sbjct: 705  RNVNQKLHSDLEHMKRHIEEKKKHL-----ELSLDEERA----KLLQNLEES--SKTMKH 753

Query: 714  IQE-NMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELS 772
            ++E ++ LT++L ++     +E LAK+  E  + ++     +     + L I+N+E E+ 
Sbjct: 754  LEETSLALTEELNELKIR--NEELAKVAEERDTLLKKLTESEENNSLQALQIQNLEEEMV 811

Query: 773  KYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMD 832
            K    +   +  I  +E++  SL+   ++  +  Q+            +E    L   +D
Sbjct: 812  KTVQTLEETKRKIQELEEKNNSLQHSLEEERNVNQKLTTELEHVKRHIEEKKKDLESTLD 871

Query: 833  HDRVVEKQLLEIEHEN-KELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAES 891
             +R    Q LE   +  K L++    L EE   L+I+ + + +  + LV+K   ++   S
Sbjct: 872  EERAKLLQKLEESSKTMKHLEETGFALTEELNELKINNAKVAEERDTLVKKLTDSEETNS 931

Query: 892  ESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDK-----KVL 946
              T     L +   NL       +   ++  +E+E+ E     +++  + DK     + L
Sbjct: 932  LQTLKIQNLEEEMRNLFASLENERKNSIKAGEELEEKEANLK-KLKMLLEDKENDFVRQL 990

Query: 947  NEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQ 1006
            +EK E  ++ + ++E ++   K  ++  N N+   N   +E+ +  ++ +  Q     E 
Sbjct: 991  DEK-ESRLKKIEEMEEEISSLKKLLDEANNNLAVKNHQ-IEIYEADLKTKNGQ----IEA 1044

Query: 1007 YINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESK-LAQFTTKLENMEE--- 1062
               +I + N L+++++E    +   ++N      ++  + ++K L     KL+N E+   
Sbjct: 1045 LSRKIEEYNDLIEERNEGFFKI---LSNFSEPLNNVRRNKDNKHLYNLEQKLQNFEQTFS 1101

Query: 1063 -EMQRVSKQLLDSKQHNEELQILVREQDDQIKELKET-KLTFEMNIPKTEGMIISSTIEP 1120
             E + ++K L+  KQ  E+   L  E+++ ++++ E  K   E+N  ++        I  
Sbjct: 1102 LERENLAKILIYLKQFEEKHSALEEEKEELLRQITELRKQIVEVNSAQSYVKQFEEEILR 1161

Query: 1121 MSDDANNVDXXXXXXXXXXXXLKVQEEE-EFIQERSVLQEQSAKLNTELQECYTKIIQLE 1179
            + ++  NV             L+++    + + + + L E++  L TE++E   K  + E
Sbjct: 1162 LREE--NVRLMEEQEKFKQNVLELESRNTQVVSDSNFLSEENHGLLTEIEELKLKNEEYE 1219

Query: 1180 TLNTELTGH-----DVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFE 1234
            T +  L           NQ Q+ +L+  L +L  E   LL  + EL+++  +A ++    
Sbjct: 1220 TKHKNLLSQIENLERESNQSQLAELEKHLTELQHEKQLLLEEIDELKTTPINAANKSEDY 1279

Query: 1235 IAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTS 1294
            + E+  ++L  +   ++  +   R  +  +E++ ++L +  +   ++    +VT+   + 
Sbjct: 1280 VKEI--ENLRTKIVQYKSLDLTNRSSIEFYENELQKLKNQNEKLNRKLDETLVTLNHCSE 1337

Query: 1295 LQNKLQDKEEHLRNLQEKY 1313
            L N  +   E+L+N+   Y
Sbjct: 1338 LSNSTE--IEYLKNVLYNY 1354



 Score =  130 bits (315), Expect = 2e-28
 Identities = 288/1383 (20%), Positives = 579/1383 (41%), Gaps = 108/1383 (7%)

Query: 213  DTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHS 272
            D  Q  +   ENF ++ AE       L+   E+K  R S+   A+ +    R+E      
Sbjct: 29   DRLQNSSTSDENFFSI-AEDGFTNVSLVSPQENKMRRNSNSSIASDVSFLPRYESFANMY 87

Query: 273  KLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLE 332
             L  +L+               L   S E       + + +        T+L K  + LE
Sbjct: 88   HLQSDLDISASEIEDNASNSSQLGHLSKEQIYSAFQKAQMRYHKYRGRYTDLAKHYKDLE 147

Query: 333  HLNCQIRQTNKELENKLATMGTESK---AVSSPSKKGSPLISRKSGRNTASKMKSPWSQL 389
              N +++    E ++K     TE K   A+   +K       R        K++S  +++
Sbjct: 148  RENAKMKSVLVETQDKAIRRVTELKEQCALEQKAKAHLESALRDEIDEKQFKIESLQTKI 207

Query: 390  ----SSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGK 445
                + ET N DT  K   +   ++E + Q + +++     +   K+            +
Sbjct: 208  ELLQTPETENPDTLNKYLTDARVEIENLNQRI-QEMKANSIIFQTKEQEYKAKITNLEKE 266

Query: 446  DTLIAQLQLEHQQHMEGPSL-IHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKD---- 500
              L ++ + E+   +    + +H    ++D  EI+ +++ L+       K  N++     
Sbjct: 267  IALFSEREKENNLSLAQNKMELHNELLSKDA-EISNLKKSLEALTGGTGKFENLQTQNTK 325

Query: 501  LIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRL 560
            LIEKL++  ++     +++    +   + + N +LK K++Q        V +  K+ +  
Sbjct: 326  LIEKLEALTQKCNNYENKLLKMEQLRRENEENSRLK-KEIQDIQGQLEGVREEAKKSLLS 384

Query: 561  TEELHHLSQKVA-ELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLL 619
             E    + +K+A E EE++  L+      D  + IE +V        NL E   + I  L
Sbjct: 385  LET--KIREKLAKEFEEKEERLRS-----DFRKKIE-EVSSSSSNEFNLLEME-EEIRKL 435

Query: 620  ESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELA 679
                  ++++L     KYD++E    ++ + +S ++ S+I    LE+++  L  + +   
Sbjct: 436  RQVNDGILEQLTSKTTKYDDLERNHLELIE-ESGRLRSQIGG--LEKELATLQNTNQAAN 492

Query: 680  LVIENLKLDKEQLYGTIKD---LENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELL 736
            L + +L+ +   L  T+++   LE +++D++ + +N+++   DL +  E+   E+++  +
Sbjct: 493  LKLGHLEANARVLERTVEEYKRLEAERDDLLQEKKNFME---DLEE--ERRINERLNLEV 547

Query: 737  AKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAV-MEDRRYSL 795
             ++  E   K   +  ++   +ER +  + + +EL   K  I   ++ + + +++ +  L
Sbjct: 548  EQLRDEMVKKSDLEHSLE---EERKV-TQKLNTELENVKCHIEEKKKDLELTLDEEKGKL 603

Query: 796  ERKADQLG---SYLQEKQKAYSEYTIQEDELVNR-LAVLMDHDRVVEKQLLEIEHENKEL 851
             +K ++      +L++   A SE  +   +L N  LA L +    + K+L E E  N   
Sbjct: 604  LQKLEESSVNMKHLEDTGLALSE-ELNSLKLKNEELAKLAEERDTLLKKLTESEETNSLQ 662

Query: 852  QKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRIT 911
             +K Q L EE     +SL + ++    L E+ N       E      +L     ++KR  
Sbjct: 663  TRKIQNLEEEMAKKAVSLEEAKRKILELGEQNNSLGHNLEEERNVNQKLHSDLEHMKR-- 720

Query: 912  HEHQTLIVQKKKEIE-DLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNN 970
              H   I +KKK +E  L+ E    +++     K +    E ++     L  +L E K  
Sbjct: 721  --H---IEEKKKHLELSLDEERAKLLQNLEESSKTMKHLEETSLA----LTEELNELKIR 771

Query: 971  IENLNMNVEELNKMNLELIDKHVQK--QQTQSPDYTEQYINEINKLNALLKQKDEEIIAL 1028
             E L    EE + +  +L +       Q  Q  +  E+ +  +  L    K+K +E   L
Sbjct: 772  NEELAKVAEERDTLLKKLTESEENNSLQALQIQNLEEEMVKTVQTLEET-KRKIQE---L 827

Query: 1029 NQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQIL--VR 1086
             +K N+ Q S    + +  +   + TT+LE+++  ++   K L +S    E  ++L  + 
Sbjct: 828  EEKNNSLQHS----LEEERNVNQKLTTELEHVKRHIEEKKKDL-ESTLDEERAKLLQKLE 882

Query: 1087 EQDDQIKELKET--KLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKV 1144
            E    +K L+ET   LT E+N  K     ++   + +     + +            L+ 
Sbjct: 883  ESSKTMKHLEETGFALTEELNELKINNAKVAEERDTLVKKLTDSEETNSLQTLKIQNLEE 942

Query: 1145 QEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLE 1204
            +    F    +  ++ S K   EL+E    + +L+ L  E   +D V Q  +++ +S+L+
Sbjct: 943  EMRNLFASLENE-RKNSIKAGEELEEKEANLKKLKML-LEDKENDFVRQ--LDEKESRLK 998

Query: 1205 QLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAF 1264
            ++  E +  +S++ +L    ++ +  +  +I E+++  L  +    +    ++       
Sbjct: 999  KIE-EMEEEISSLKKLLDEANNNLAVKNHQI-EIYEADLKTKNGQIEALSRKIEEYNDLI 1056

Query: 1265 ESKYEQLLDSVQSSTQEETNKI---VTMEQVTSLQNKLQDKEEHLRNLQEKYADVI---N 1318
            E + E     + S+  E  N +      + + +L+ KLQ+ E+     +E  A ++    
Sbjct: 1057 EERNEGFF-KILSNFSEPLNNVRRNKDNKHLYNLEQKLQNFEQTFSLERENLAKILIYLK 1115

Query: 1319 QIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLK 1378
            Q E   S +E+EK                         QSY +  E+ IL + EEN +L 
Sbjct: 1116 QFEEKHSALEEEKEELLRQITELRKQIVEV-----NSAQSYVKQFEEEILRLREENVRLM 1170

Query: 1379 KSSXXXXXXXXXXXXR----VNDAEAKVLELTHQLELKDSEIYQKTHEYTI----TLTQ- 1429
            +              R    V+D+   + E  H L  +  E+  K  EY       L+Q 
Sbjct: 1171 EEQEKFKQNVLELESRNTQVVSDSNF-LSEENHGLLTEIEELKLKNEEYETKHKNLLSQI 1229

Query: 1430 RNDEFENVRQQLVEYEKRIEDLTYEKE---SELAILRLKMHENANHYETMQKESEIERVK 1486
             N E E+ + QL E EK + +L +EK+    E+  L+      AN  E   KE E  R K
Sbjct: 1230 ENLERESNQSQLAELEKHLTELQHEKQLLLEEIDELKTTPINAANKSEDYVKEIENLRTK 1289

Query: 1487 LIEELNVKITESVSLNKQVAELNKALEEEVAKTNEM--QTALENQEIEIVTLNDEITNLQ 1544
            +++  ++ +T   S+     EL K L+ +  K N    +T +       ++ + EI  L+
Sbjct: 1290 IVQYKSLDLTNRSSIEFYENELQK-LKNQNEKLNRKLDETLVTLNHCSELSNSTEIEYLK 1348

Query: 1545 NMV 1547
            N++
Sbjct: 1349 NVL 1351



 Score =  125 bits (302), Expect = 9e-27
 Identities = 171/870 (19%), Positives = 376/870 (43%), Gaps = 55/870 (6%)

Query: 143  DVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXX 202
            ++  L NT +  +  L  L+   +++E T+ + +    E+D +++ K K           
Sbjct: 480  ELATLQNTNQAANLKLGHLEANARVLERTVEEYKRLEAERDDLLQEK-KNFMEDLEEERR 538

Query: 203  XXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEA 262
                     E  + +M K  +   ++E E K   Q+L  ++E+    I   EE  K LE 
Sbjct: 539  INERLNLEVEQLRDEMVKKSDLEHSLEEERK-VTQKLNTELENVKCHI---EEKKKDLEL 594

Query: 263  ARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQ--SIEPSCEEKTEIEEKGSLEIAN 320
               E   E  KL Q+LE+              L+++  S++   EE  ++ E+    +  
Sbjct: 595  TLDE---EKGKLLQKLEESSVNMKHLEDTGLALSEELNSLKLKNEELAKLAEERDTLLKK 651

Query: 321  MTE-------LTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRK 373
            +TE        T+KI+ LE    +   + +E + K+  +G ++ ++   + +    +++K
Sbjct: 652  LTESEETNSLQTRKIQNLEEEMAKKAVSLEEAKRKILELGEQNNSLGH-NLEEERNVNQK 710

Query: 374  SGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDT 433
               +     +    +     L+ D ++      + +    ++ L +  +     ++E   
Sbjct: 711  LHSDLEHMKRHIEEKKKHLELSLDEERAKLLQNLEESSKTMKHLEETSLALTEELNELKI 770

Query: 434  XXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELND-E 492
                       +DTL+   +L   +       + +    E++ +  +  E+ K+++ + E
Sbjct: 771  RNEELAKVAEERDTLLK--KLTESEENNSLQALQIQNLEEEMVKTVQTLEETKRKIQELE 828

Query: 493  IKDVNVKDLIEKLKSAEEQIT----QLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFS 548
             K+ +++  +E+ ++  +++T     +   I+   K++       + KL  +QK  ++  
Sbjct: 829  EKNNSLQHSLEEERNVNQKLTTELEHVKRHIEEKKKDLESTLDEERAKL--LQKLEESSK 886

Query: 549  KVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENL 608
             +    +    LTEEL+ L    A++ EE+  L   L D +    +++      ++++NL
Sbjct: 887  TMKHLEETGFALTEELNELKINNAKVAEERDTLVKKLTDSEETNSLQT------LKIQNL 940

Query: 609  AETRLKAISLLESQKFDLVQELHILQQKYDE-------VEDKLADISQLQSDQVCSEIKS 661
             E      + LE+++ + ++    L++K          +EDK  D  + Q D+  S +K 
Sbjct: 941  EEEMRNLFASLENERKNSIKAGEELEEKEANLKKLKMLLEDKENDFVR-QLDEKESRLKK 999

Query: 662  VHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLT 721
            +  EE  + +S+ KK L     NL +   Q+     DL+  K   +  L   I+E  DL 
Sbjct: 1000 I--EEMEEEISSLKKLLDEANNNLAVKNHQIEIYEADLKT-KNGQIEALSRKIEEYNDLI 1056

Query: 722  DKLEKMSAEKISELLAKINHEEQSKIQTQ-FGIDAKIQERDLYIENIESELSKYKSRICR 780
            ++  +   + +S     +N+  ++K     + ++ K+Q  +         L+K    + +
Sbjct: 1057 EERNEGFFKILSNFSEPLNNVRRNKDNKHLYNLEQKLQNFEQTFSLERENLAKILIYLKQ 1116

Query: 781  LEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRL----AVLMDHDRV 836
             EE  + +E+ +  L R+  +L   + E   A S Y  Q +E + RL      LM+    
Sbjct: 1117 FEEKHSALEEEKEELLRQITELRKQIVEVNSAQS-YVKQFEEEILRLREENVRLMEEQEK 1175

Query: 837  VEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTK- 895
             ++ +LE+E  N ++   +  L EEN  L   + +++   N   E  ++  L++ E+ + 
Sbjct: 1176 FKQNVLELESRNTQVVSDSNFLSEENHGLLTEIEELKLK-NEEYETKHKNLLSQIENLER 1234

Query: 896  --YQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKN 953
               Q+QL +LE +L  + HE Q L++++  E++   I    + E  +++ + L  K  + 
Sbjct: 1235 ESNQSQLAELEKHLTELQHEKQ-LLLEEIDELKTTPINAANKSEDYVKEIENLRTKIVQY 1293

Query: 954  IEYVTQLEAQLQEYKNNIENLNMNVEELNK 983
                    + ++ Y+N ++ L    E+LN+
Sbjct: 1294 KSLDLTNRSSIEFYENELQKLKNQNEKLNR 1323



 Score = 75.4 bits (177), Expect = 1e-11
 Identities = 184/918 (20%), Positives = 380/918 (41%), Gaps = 71/918 (7%)

Query: 700  ENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQE 759
            E   E++ +  Q + Q    ++D+L+  S     E    I  +  + +      + K++ 
Sbjct: 7    EKITEEVKSSPQRFQQLTQSVSDRLQNSSTS--DENFFSIAEDGFTNVSLVSPQENKMRR 64

Query: 760  R-DLYIENIESELSKYKS--RICRLEESIAVMEDRRYSLERKADQLGSYLQEK-QKAYSE 815
              +  I +  S L +Y+S   +  L+  + +           + QLG   +E+   A+ +
Sbjct: 65   NSNSSIASDVSFLPRYESFANMYHLQSDLDISASEIEDNASNSSQLGHLSKEQIYSAFQK 124

Query: 816  YTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQH 875
              ++  +   R   L  H + +E++  +++    E Q K    + E +  Q +L   +Q 
Sbjct: 125  AQMRYHKYRGRYTDLAKHYKDLERENAKMKSVLVETQDKAIRRVTELKE-QCAL---EQK 180

Query: 876  YNALVEKANRTDLAESEST--KYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFN 933
              A +E A R ++ E +      QT++  L++            +   + EIE+L    N
Sbjct: 181  AKAHLESALRDEIDEKQFKIESLQTKIELLQTPETENPDTLNKYLTDARVEIENL----N 236

Query: 934  TQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNL--ELIDK 991
             +I+    +  +   K ++    +T LE ++  +    +  N+++ + NKM L  EL+ K
Sbjct: 237  QRIQEMKANSIIFQTKEQEYKAKITNLEKEIALFSEREKENNLSLAQ-NKMELHNELLSK 295

Query: 992  HVQ-KQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKL 1050
              +     +S +       +   L     +  E++ AL QK NN +   + M      +L
Sbjct: 296  DAEISNLKKSLEALTGGTGKFENLQTQNTKLIEKLEALTQKCNNYENKLLKM-----EQL 350

Query: 1051 AQFTTKLENMEEEMQRVSKQLL----DSKQHNEELQILVREQDDQIKELKETKLTFEMNI 1106
             +   +   +++E+Q +  QL     ++K+    L+  +RE+  +  E KE +L  +   
Sbjct: 351  RRENEENSRLKKEIQDIQGQLEGVREEAKKSLLSLETKIREKLAKEFEEKEERLRSDFR- 409

Query: 1107 PKTEGMIISSTIE----PMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSA 1162
             K E +  SS+ E     M ++   +              K  + ++  +    L E+S 
Sbjct: 410  KKIEEVSSSSSNEFNLLEMEEEIRKLRQVNDGILEQLTS-KTTKYDDLERNHLELIEESG 468

Query: 1163 KLNTELQECYTKIIQLETLNTELT---GHDVVNQEQINQLKSKLEQLNTENDNLLSTVAE 1219
            +L +++     ++  L+  N       GH   N   + +   + ++L  E D+LL     
Sbjct: 469  RLRSQIGGLEKELATLQNTNQAANLKLGHLEANARVLERTVEEYKRLEAERDDLLQEKKN 528

Query: 1220 LRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSST 1279
                +    ++R  E   L  + L          EH L  +    + K    L++V+   
Sbjct: 529  FMEDLEE--ERRINERLNLEVEQLRDEMVKKSDLEHSLEEERKVTQ-KLNTELENVKCHI 585

Query: 1280 QEETNKI-VTM-EQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXX 1337
            +E+   + +T+ E+   L  KL++   ++++L++    +  ++  L+  +++E++A    
Sbjct: 586  EEKKKDLELTLDEEKGKLLQKLEESSVNMKHLEDTGLALSEELNSLK--LKNEELAKLAE 643

Query: 1338 XXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVND 1397
                            TE++    +Q + I N+ EE A+ K  S              N+
Sbjct: 644  ERDTLLKKL-------TESEETNSLQTRKIQNLEEEMAK-KAVSLEEAKRKILELGEQNN 695

Query: 1398 AEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKES 1457
            +      L H LE ++  + QK H   +   +R+ E +    +L   E+R + L   +ES
Sbjct: 696  S------LGHNLE-EERNVNQKLHS-DLEHMKRHIEEKKKHLELSLDEERAKLLQNLEES 747

Query: 1458 ELAILRLKMHENANHYETMQ-KESEIERVKLIEELNV---KITESVSLNKQVAELNKALE 1513
               +  L+    A   E  + K    E  K+ EE +    K+TES   N   A   + LE
Sbjct: 748  SKTMKHLEETSLALTEELNELKIRNEELAKVAEERDTLLKKLTESEENNSLQALQIQNLE 807

Query: 1514 EEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQ-- 1571
            EE+ KT  +QT LE  + +I  L ++  +LQ+ +    +  QK  +     K+  +E+  
Sbjct: 808  EEMVKT--VQT-LEETKRKIQELEEKNNSLQHSLEEERNVNQKLTTELEHVKRHIEEKKK 864

Query: 1572 -LDNTMNKELLDAVPRAE 1588
             L++T+++E    + + E
Sbjct: 865  DLESTLDEERAKLLQKLE 882



 Score = 68.1 bits (159), Expect = 2e-09
 Identities = 145/710 (20%), Positives = 274/710 (38%), Gaps = 57/710 (8%)

Query: 73   EHRKATAELLGRPFVPGISESLANTLKQKEILMEKIKQYKELSKRSSTTIVRXXXXXXXX 132
            EH K   E   +     + E  A  L+  E   E  K  K L + S              
Sbjct: 716  EHMKRHIEEKKKHLELSLDEERAKLLQNLE---ESSKTMKHLEETSLALTEELNELKIRN 772

Query: 133  XXXXXXXQLGDVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQ--EKINEKDQIIEAKN 190
                   +  D      T  E++N+L  LQ++  + E  +  +Q  E+   K Q +E KN
Sbjct: 773  EELAKVAEERDTLLKKLTESEENNSLQALQIQ-NLEEEMVKTVQTLEETKRKIQELEEKN 831

Query: 191  KATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRI 250
             +                   E  K+ + + +++   +E+   +E+ +LL+ +E     +
Sbjct: 832  NSLQHSLEEERNVNQKLTTELEHVKRHIEEKKKD---LESTLDEERAKLLQKLEESSKTM 888

Query: 251  SSLEEANKLLEAARFEISLEHSKLAQELEQ--XXXXXXXXXXXXXXLAKQSIEPSCEE-- 306
              LEE    L     E+ + ++K+A+E +                 L  Q++E       
Sbjct: 889  KHLEETGFALTEELNELKINNAKVAEERDTLVKKLTDSEETNSLQTLKIQNLEEEMRNLF 948

Query: 307  -KTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKK 365
               E E K S++     EL +K   L+ L   +     +   +L    +  K +    ++
Sbjct: 949  ASLENERKNSIKAGE--ELEEKEANLKKLKMLLEDKENDFVRQLDEKESRLKKIEEMEEE 1006

Query: 366  GSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDK- 424
             S L       N    +K+   ++       + D K    +I  L   I+  N DL+++ 
Sbjct: 1007 ISSLKKLLDEANNNLAVKNHQIEI------YEADLKTKNGQIEALSRKIEEYN-DLIEER 1059

Query: 425  -EYVISEKDTXXXXXXXXXXGKD-----TLIAQLQ-LEHQQHMEGPSLIHVGTNTEDVNE 477
             E                   KD      L  +LQ  E    +E  +L  +    +   E
Sbjct: 1060 NEGFFKILSNFSEPLNNVRRNKDNKHLYNLEQKLQNFEQTFSLERENLAKILIYLKQFEE 1119

Query: 478  IAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEI-DAANKNMIKVKSNHKLK 536
                 E+ K+EL  +I ++  K ++E + SA+  + Q  +EI     +N+  ++   K K
Sbjct: 1120 KHSALEEEKEELLRQITELR-KQIVE-VNSAQSYVKQFEEEILRLREENVRLMEEQEKFK 1177

Query: 537  LKQMQKTIDNFSKVSDSN---KEIVRLTEELHHLSQKVAELEEEKGNL--QLHLVDYDSG 591
               ++    N   VSDSN   +E   L  E+  L  K  E E +  NL  Q+  ++ +S 
Sbjct: 1178 QNVLELESRNTQVVSDSNFLSEENHGLLTEIEELKLKNEEYETKHKNLLSQIENLERESN 1237

Query: 592  RMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQ 651
            +   +++ K + E+++  +  L+ I  L++   +   +    +    E+E+    I Q +
Sbjct: 1238 QSQLAELEKHLTELQHEKQLLLEEIDELKTTPINAANK---SEDYVKEIENLRTKIVQYK 1294

Query: 652  SDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQL-YGTIKDLEN--DKEDIMN 708
            S  + +       E ++  L    ++L     N KLD+  +      +L N  + E + N
Sbjct: 1295 SLDLTNRSSIEFYENELQKLKNQNEKL-----NRKLDETLVTLNHCSELSNSTEIEYLKN 1349

Query: 709  KLQNYI--QENMDLTDKLE---KMSAEKISELLAKINHEEQSKIQTQFGI 753
             L NY+  +E+M L   +    K   ++   +LAK   +++  +  Q GI
Sbjct: 1350 VLYNYMLGKESMVLARVIAAVCKFDPQQTELILAK--EQQKQTLLGQLGI 1397


>UniRef50_UPI00015A607A Cluster: UPI00015A607A related cluster; n=1;
            Danio rerio|Rep: UPI00015A607A UniRef100 entry - Danio
            rerio
          Length = 2332

 Score =  148 bits (358), Expect = 1e-33
 Identities = 283/1380 (20%), Positives = 592/1380 (42%), Gaps = 116/1380 (8%)

Query: 248  VRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEK 307
            +++ +L +   +L+    EI    + L +E  Q              L K   + + E+K
Sbjct: 738  MQVDTLTQTKDVLQG---EIQCLQTDLERETAQKERELQESKKRNTELEKLQTKSAAEQK 794

Query: 308  T-EIEEKGSL-EIANMTELTKKIEL-LEHLNCQ-IRQTNKELENKLATMGTESKAVSSPS 363
              E+  +G+  E+    E   K++   E LN + + +  +E +N   T   ++K +S   
Sbjct: 795  AAELRLRGACDEVERWKERENKVQREKEELNQKFLERVERESQNLEITQREKAK-MSDLM 853

Query: 364  KKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKIN-KNEIAKLEMVIQSLNKDLV 422
            KK    I R+       K+K   ++ + E+L  +  +K   ++ +  LE +   L +  +
Sbjct: 854  KKKEDEIRRRGEDIEELKLKLQSNEKTIESLEIELQQKETLESRVETLEKLNTQLKEKKL 913

Query: 423  DKEYVISEKDTXXXXXXXXXXGKDTLIA-QLQLEHQQHMEGPSLIHVGTNTED-----VN 476
            DK   I E ++           K+     QL+ + +  +E  S I      ++     V 
Sbjct: 914  DK---IRENESRQKKRDEQEREKEVRWRRQLEQKDEGLIELKSRIDELIGEKEHISLLVE 970

Query: 477  EIAKVQEQLKQELNDEIK--DVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHK 534
            E  K  EQL+  L+ E +  ++ +K+  E+L+   EQI+Q+ +      K + +++ N K
Sbjct: 971  EREKDIEQLQSTLSTEKRALELRLKEKNEQLELLNEQISQIKEREIENQKELDRMQENLK 1030

Query: 535  LKLKQMQKTIDN----FSKVSDSNKEIVRLTEELHHLSQKV-AELEEEKGNL-QLHLVDY 588
             + KQ+++ +D+     + V    +E++   EE     QK+ AE  E+   + QL L   
Sbjct: 1031 EQEKQLKRELDHLNIKMAGVIQEKEELLERIEEQRMFEQKLKAEHAEKDVEVRQLKLKIE 1090

Query: 589  DSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADIS 648
            +  + IE D   +M + E+L +      +LL   + +       LQQK  E  D+L    
Sbjct: 1091 ELNQEIEQDRRIRMEQQEDLEQ----QTALLRDAEEEARTLKKTLQQKDKEERDRL---H 1143

Query: 649  QLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKED--I 706
              + ++   + K    E++   + +S +E+   +E    ++ QL G  + L    E+  +
Sbjct: 1144 HEEKEKTLLKEKLHEAEQRNIKVLSSLQEIETTLEK---ERYQLRGKEERLMECNEELFL 1200

Query: 707  MNKLQNYIQENMDLTDKLEKMSAEKISELLAKINH--EEQSKIQTQF-GIDAKIQERDLY 763
            + + ++  +E+++  +KL     +++  L  K++   EE+ ++         ++Q  +  
Sbjct: 1201 IKRERDQEKESIEELNKLIGEQGKEVKTLRGKLDERLEEEGRLSKLLQNQRVEVQVLESR 1260

Query: 764  IENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYT-IQEDE 822
             ENIE E  + K  + ++EE    +E +    +   ++L   L+++    ++   I E+E
Sbjct: 1261 AENIEEEKQQLKRSLSQIEEEKRHLETQLTDEKVDKERLRVRLEDQATEVTKLNKILEEE 1320

Query: 823  LVNRLAVLMDHDRVVEKQLLEIEHEN----KELQKKNQILLE-ENQNLQISLSDMQQHYN 877
               +L+ L+ + R VE Q+ E   +N    K+L K++   +E E   L+  L+D +    
Sbjct: 1321 --RKLSQLLQNSR-VEAQMFESRAQNTEEEKQLLKRSLSQIEREKSRLETQLTDEKMDKE 1377

Query: 878  ALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFN---- 933
             L  +    D   ++  +   ++ + E  L ++    +      +   E++E+E      
Sbjct: 1378 KLKARLEDQDKEVTKLKEKMNEILEEERKLSQLLQNSRVEAQMLESRAENIEVEKQQLKR 1437

Query: 934  --TQIESAIR--DKKVLNEKYEKNIEYVTQ-LEAQLQEYKNNIENLNMNVEELNK----M 984
              TQIE   R    ++ +EK +KN       LE++ +  +   + L  ++ ++ K    +
Sbjct: 1438 SLTQIEEEKRHLGTQLTDEKMDKNSRVEAHILESRTENIEEEKQQLTRSLTQIEKEKRHL 1497

Query: 985  NLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVS 1044
              +L D+ + K++ ++    +    E+ KL   L +  EE   L+Q + N++V    + S
Sbjct: 1498 ETQLTDEKMDKERLRA--RLKDQATEVTKLKEKLNEMIEEERKLSQLLQNSRVEAQMLES 1555

Query: 1045 DYESKL---AQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLT 1101
              E+ +    Q    L  +EEE + +  QL D K   E L+  + +Q  ++ +LK   L 
Sbjct: 1556 RAENTIEEKQQLKRVLSQVEEEKRLLETQLTDEKIDRERLKARLEDQATEVTKLKTENLE 1615

Query: 1102 FEMNIPK-------TEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXL---KVQEEEEFI 1151
             E    K        E   + + +     D   +             L   K+   E+  
Sbjct: 1616 EEKQQLKRSLTQIEEEKRCLETQLTDEKIDRERLRARLEDFQKDQQILFEEKMGRAEKLG 1675

Query: 1152 QERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTEND 1211
                 L+EQ   L+ EL+    K  ++E L  E        ++++  LK  LE+ + E +
Sbjct: 1676 SRVRELEEQRDHLSAELRR---KEREMEVLRDETLRER--REKEMATLKELLEESHREGE 1730

Query: 1212 NLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQR----EADFQKTEHELRVQLSAFESK 1267
             L S + E +  +  + ++ G ++A +  + L  +    E   Q+ E  L++Q+   + K
Sbjct: 1731 RLRSMMQERKDELVRSREE-GIKVAHIEAKDLQLKVQMLEKQKQELETTLQLQVEQLKKK 1789

Query: 1268 YEQ-LLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSE 1326
             E+ + +  Q   ++E  +    +    L N+ +D       L+E      N  E L+ E
Sbjct: 1790 NEEGMQEKEQLQQRQEKLEAERTKDAEELSNRFRDLRLEADRLREDRIREKNNWEELKRE 1849

Query: 1327 IEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXX 1386
             ++++ A                 +++   + Y+  + +S      +   +++       
Sbjct: 1850 NKEKQNAL-EELELLRKTLMEKEKEMKLVKEKYENEKRRSERFQQGDEQNVRQIELVSER 1908

Query: 1387 XXXXXXXRVNDAEAKVLELTHQLELKD-----SEIYQKTHEYTITLTQRNDEFENVRQQL 1441
                     +  E    E + +L L+D       + +K  E   TL + N E+ +   +L
Sbjct: 1909 LRDKETELESIREKAYKEQSARLRLQDQFEDEKRVTKKLREKLETLEKINAEYRS-HVKL 1967

Query: 1442 VEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERV-KLIEELNVKI--TES 1498
            +E +   +DLT +K+ E+  LR+K        ET+Q  +EI+R+  L++  N+K   TE+
Sbjct: 1968 LEADTLRKDLT-KKDQEIRRLRIKA-------ETLQ--TEIDRLHSLLKNGNMKTGPTEN 2017

Query: 1499 VSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLN---DEITNLQNMVRASSSKIQ 1555
               +++  +++  L E+     E    L  +++E+  L    +E++  ++ VR +  K +
Sbjct: 2018 EDWDREKQQVSTILLEK----EERDRLLREKDVEVYALKERAEEMSKDRDRVRIALEKTE 2073



 Score =  132 bits (320), Expect = 6e-29
 Identities = 243/1164 (20%), Positives = 495/1164 (42%), Gaps = 122/1164 (10%)

Query: 508  AEEQITQLNDEIDAANKNMIKVKSNH-KLKLKQMQKTIDNF-SKVSDSNKEIVRLTEELH 565
            A E++  LN+ + A +K  + V+S   + ++ + Q  I  F ++ +  ++E+  ++ E+H
Sbjct: 546  ALEKMAALNEAL-AKDKRELGVRSLQLETEVAEAQAQIQAFGTETAGLHRELKAMSLEVH 604

Query: 566  HLSQKVAELEEE--------KGNLQLHLVDYDSGRMIESDVYKK----MIEMENLAETRL 613
             L ++  ELE E        +        D  +     S++ ++    M E++++    L
Sbjct: 605  ELRERERELENELELEREDRQREQTARTEDKSTDEQKISELTEQCSTVMKELQSVKVELL 664

Query: 614  KAISL---LESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQ----VCSEIKSVHLEE 666
            KA  L    E ++ DL++E   L+     +E +  +++Q++ +     VC + +    +E
Sbjct: 665  KAAELQRRAERERDDLMRESQRLEDTVCTLEREKEELAQVKEELRGVVVCLQKQMAQAQE 724

Query: 667  QIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEK 726
            Q   L     +L + ++ L   K+ L G I+ L+ D E    + +  +QE+     +LEK
Sbjct: 725  QTSGLELKCIQLQMQVDTLTQTKDVLQGEIQCLQTDLERETAQKERELQESKKRNTELEK 784

Query: 727  MSAEKISE-------LLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESE---LSKYKS 776
            +  +  +E       L    +  E+ K +       K +    ++E +E E   L   + 
Sbjct: 785  LQTKSAAEQKAAELRLRGACDEVERWKERENKVQREKEELNQKFLERVERESQNLEITQR 844

Query: 777  RICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTI---QEDELVNRLAVLMDH 833
               ++ + +   ED         ++L   LQ  +K      I   Q++ L +R+  L   
Sbjct: 845  EKAKMSDLMKKKEDEIRRRGEDIEELKLKLQSNEKTIESLEIELQQKETLESRVETLEKL 904

Query: 834  DRVVEKQLLEIEHENKELQKKNQILLEENQNLQIS-LSDMQQHYNALVEKANRTD--LAE 890
            +  ++++ L+   EN+  QKK     E+ +  ++     ++Q    L+E  +R D  + E
Sbjct: 905  NTQLKEKKLDKIRENESRQKKRD---EQEREKEVRWRRQLEQKDEGLIELKSRIDELIGE 961

Query: 891  SE--STKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNE 948
             E  S   + + +D+E     ++ E + L ++ K++ E LE+  N QI S I+++++ N+
Sbjct: 962  KEHISLLVEEREKDIEQLQSTLSTEKRALELRLKEKNEQLEL-LNEQI-SQIKEREIENQ 1019

Query: 949  KYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYI 1008
            K    ++    L+ Q ++ K  +++LN+ +  + +   EL+++  +++  +     E   
Sbjct: 1020 KELDRMQ--ENLKEQEKQLKRELDHLNIKMAGVIQEKEELLERIEEQRMFEQKLKAEHAE 1077

Query: 1009 NEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVS 1068
             ++      LK K EE   LNQ+I   +   M    D E    Q T  L + EEE + + 
Sbjct: 1078 KDVEVRQ--LKLKIEE---LNQEIEQDRRIRMEQQEDLE----QQTALLRDAEEEARTLK 1128

Query: 1069 KQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGM-IISSTIEPMSDDANN 1127
            K L   ++  EE   L  E+ ++    ++     + NI     +  I +T+E        
Sbjct: 1129 KTL--QQKDKEERDRLHHEEKEKTLLKEKLHEAEQRNIKVLSSLQEIETTLEKERYQLRG 1186

Query: 1128 VDXXXXXXXXXXXXLKVQ--EEEEFIQE-RSVLQEQS-------AKLNTELQE--CYTKI 1175
             +            +K +  +E+E I+E   ++ EQ         KL+  L+E    +K+
Sbjct: 1187 KEERLMECNEELFLIKRERDQEKESIEELNKLIGEQGKEVKTLRGKLDERLEEEGRLSKL 1246

Query: 1176 IQLETLNTELTGHDVVN-QEQINQLKSKLEQLNTENDNLLSTVAEL---RSSISSAVDQR 1231
            +Q + +  ++      N +E+  QLK  L Q+  E  +L + + +    +  +   ++ +
Sbjct: 1247 LQNQRVEVQVLESRAENIEEEKQQLKRSLSQIEEEKRHLETQLTDEKVDKERLRVRLEDQ 1306

Query: 1232 GFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYE------QLLDSVQSSTQEETNK 1285
              E+ +L K  + + E    +     RV+   FES+ +      QLL    S  + E ++
Sbjct: 1307 ATEVTKLNK--ILEEERKLSQLLQNSRVEAQMFESRAQNTEEEKQLLKRSLSQIEREKSR 1364

Query: 1286 I---VTMEQV--TSLQNKLQDKEEHLRNLQEKYADVINQ-----------------IEIL 1323
            +   +T E++    L+ +L+D+++ +  L+EK  +++ +                 +E  
Sbjct: 1365 LETQLTDEKMDKEKLKARLEDQDKEVTKLKEKMNEILEEERKLSQLLQNSRVEAQMLESR 1424

Query: 1324 RSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSIL-----NINEENAQLK 1378
               IE EK                    L  E        E  IL     NI EE  QL 
Sbjct: 1425 AENIEVEKQQLKRSLTQIEEEKRHLGTQLTDEKMDKNSRVEAHILESRTENIEEEKQQLT 1484

Query: 1379 KSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEI---YQKTHEYTITLTQRNDEFE 1435
            +S             ++ D +     L  +L+ + +E+    +K +E      + +   +
Sbjct: 1485 RSLTQIEKEKRHLETQLTDEKMDKERLRARLKDQATEVTKLKEKLNEMIEEERKLSQLLQ 1544

Query: 1436 NVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKI 1495
            N R +    E R E+ T E++ +L  +  ++ E     ET   + +I+R +L   L  + 
Sbjct: 1545 NSRVEAQMLESRAEN-TIEEKQQLKRVLSQVEEEKRLLETQLTDEKIDRERLKARLEDQA 1603

Query: 1496 TESVSL-NKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKI 1554
            TE   L  + + E  + L+  + +  E +  LE Q      L DE  + + + RA     
Sbjct: 1604 TEVTKLKTENLEEEKQQLKRSLTQIEEEKRCLETQ------LTDEKIDRERL-RARLEDF 1656

Query: 1555 QKHVSFASDTKQGRDEQLDNTMNK 1578
            QK      + K GR E+L + + +
Sbjct: 1657 QKDQQILFEEKMGRAEKLGSRVRE 1680



 Score =  105 bits (251), Expect = 1e-20
 Identities = 185/880 (21%), Positives = 375/880 (42%), Gaps = 59/880 (6%)

Query: 246  KDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCE 305
            +D    S+EE NKL+     E+     KL + LE+              +  Q +E   E
Sbjct: 1205 RDQEKESIEELNKLIGEQGKEVKTLRGKLDERLEEEGRLSKLLQNQRVEV--QVLESRAE 1262

Query: 306  EKTEIEEKGSLEIANMTELTKKIEL-LEHLNCQIRQTNKELENKLATMGTESKAVSSPSK 364
               E +++    ++ + E  + +E  L        +    LE++ AT  T+   +    +
Sbjct: 1263 NIEEEKQQLKRSLSQIEEEKRHLETQLTDEKVDKERLRVRLEDQ-ATEVTKLNKILEEER 1321

Query: 365  KGSPLI--SRKSGRNTASKMKS--PWSQLSSETLNQ-DTDKKINKNEIAKLEMVIQSLNK 419
            K S L+  SR   +   S+ ++     QL   +L+Q + +K   + ++   +M  + L  
Sbjct: 1322 KLSQLLQNSRVEAQMFESRAQNTEEEKQLLKRSLSQIEREKSRLETQLTDEKMDKEKLKA 1381

Query: 420  DLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTN--TEDVNE 477
             L D++  +++                 L+   ++E Q        I V        + +
Sbjct: 1382 RLEDQDKEVTKLKEKMNEILEEERKLSQLLQNSRVEAQMLESRAENIEVEKQQLKRSLTQ 1441

Query: 478  IAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKL 537
            I + +  L  +L DE  D N +     L+S  E I +   ++  +   + K K + + +L
Sbjct: 1442 IEEEKRHLGTQLTDEKMDKNSRVEAHILESRTENIEEEKQQLTRSLTQIEKEKRHLETQL 1501

Query: 538  KQMQKTIDNF-SKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIES 596
               +   +   +++ D   E+ +L E+L+ +      +EEE+   QL        +M+ES
Sbjct: 1502 TDEKMDKERLRARLKDQATEVTKLKEKLNEM------IEEERKLSQLLQNSRVEAQMLES 1555

Query: 597  DVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYD------EVEDKLADISQL 650
                 + E + L     + +S +E +K   + E  +  +K D       +ED+  ++++L
Sbjct: 1556 RAENTIEEKQQLK----RVLSQVEEEK--RLLETQLTDEKIDRERLKARLEDQATEVTKL 1609

Query: 651  QSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDK----EDI 706
            +++ +  E +   L+  +  +   K+ L   + + K+D+E+L   ++D + D+    E+ 
Sbjct: 1610 KTENL--EEEKQQLKRSLTQIEEEKRCLETQLTDEKIDRERLRARLEDFQKDQQILFEEK 1667

Query: 707  MNKLQNYIQENMDLTDKLEKMSAE-KISELLAKINHEE---QSKIQTQFGIDAKIQERDL 762
            M + +       +L ++ + +SAE +  E   ++  +E   + + +    +   ++E   
Sbjct: 1668 MGRAEKLGSRVRELEEQRDHLSAELRRKEREMEVLRDETLRERREKEMATLKELLEESHR 1727

Query: 763  YIENIESELSKYKSRICR-LEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQED 821
              E + S + + K  + R  EE I V       +E K  QL   + EKQK   E T+Q  
Sbjct: 1728 EGERLRSMMQERKDELVRSREEGIKVAH-----IEAKDLQLKVQMLEKQKQELETTLQLQ 1782

Query: 822  ELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVE 881
              V +L    + + + EK+ L+   E  E ++        N+   + L   +   + + E
Sbjct: 1783 --VEQLK-KKNEEGMQEKEQLQQRQEKLEAERTKDAEELSNRFRDLRLEADRLREDRIRE 1839

Query: 882  KANRTDLAESESTKYQTQLRDLESNLKRITH-EHQTLIVQKKKEIEDLEIE-FNTQIESA 939
            K N  +L + E+ + Q  L +LE   K +   E +  +V++K E E    E F    E  
Sbjct: 1840 KNNWEEL-KRENKEKQNALEELELLRKTLMEKEKEMKLVKEKYENEKRRSERFQQGDEQN 1898

Query: 940  IRDKKVLNEKY-EKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQT 998
            +R  ++++E+  +K  E  +  E   +E    +  L    E+  ++  +L +K    ++ 
Sbjct: 1899 VRQIELVSERLRDKETELESIREKAYKEQSARL-RLQDQFEDEKRVTKKLREKLETLEKI 1957

Query: 999  QSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYES-KLAQFTTKL 1057
             +   +   + E + L   L +KD+EI  L  K    Q     + S  ++  +    T+ 
Sbjct: 1958 NAEYRSHVKLLEADTLRKDLTKKDQEIRRLRIKAETLQTEIDRLHSLLKNGNMKTGPTEN 2017

Query: 1058 ENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKE 1097
            E+ + E Q+VS  LL+     EE   L+RE+D ++  LKE
Sbjct: 2018 EDWDREKQQVSTILLE----KEERDRLLREKDVEVYALKE 2053



 Score = 61.3 bits (142), Expect = 2e-07
 Identities = 138/756 (18%), Positives = 313/756 (41%), Gaps = 55/756 (7%)

Query: 146  HLSNTIKEKDNALSVLQVKMKIMETTILDLQEKIN---EKDQIIEAKNKATTXXXXXXXX 202
            HL   + ++      L+ ++K   T +  L+EK+N   E+++ +    + +         
Sbjct: 1496 HLETQLTDEKMDKERLRARLKDQATEVTKLKEKLNEMIEEERKLSQLLQNSRVEAQMLES 1555

Query: 203  XXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEK---QRLLKDIESKDVRISSLEEANKL 259
                     +  K+ +++++E    +E +  DEK   +RL   +E +   ++ L+  N  
Sbjct: 1556 RAENTIEEKQQLKRVLSQVEEEKRLLETQLTDEKIDRERLKARLEDQATEVTKLKTEN-- 1613

Query: 260  LEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIA 319
            LE  + ++    +++ +E                 L  +  +   +++   EEK      
Sbjct: 1614 LEEEKQQLKRSLTQIEEEKRCLETQLTDEKIDRERLRARLEDFQKDQQILFEEKMGRAEK 1673

Query: 320  NMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTA 379
              + + +  E  +HL+ ++R+  +E+E        E +     + K     S + G    
Sbjct: 1674 LGSRVRELEEQRDHLSAELRRKEREMEVLRDETLRERREKEMATLKELLEESHREGERLR 1733

Query: 380  SKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVIS-EKDTXXXXX 438
            S M+    +L     +++   K+   E   L++ +Q L K   + E  +  + +      
Sbjct: 1734 SMMQERKDEL---VRSREEGIKVAHIEAKDLQLKVQMLEKQKQELETTLQLQVEQLKKKN 1790

Query: 439  XXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKD-VN 497
                  K+    QLQ + Q+ +E          T+D  E++     L+ E +   +D + 
Sbjct: 1791 EEGMQEKE----QLQ-QRQEKLE-------AERTKDAEELSNRFRDLRLEADRLREDRIR 1838

Query: 498  VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKL---KLKQMQKTIDNFSKVSDSN 554
             K+  E+LK   ++     +E++   K +++ +   KL   K +  ++  + F +  + N
Sbjct: 1839 EKNNWEELKRENKEKQNALEELELLRKTLMEKEKEMKLVKEKYENEKRRSERFQQGDEQN 1898

Query: 555  KEIVRLTEELHHLSQKVAELE--EEKG----NLQLHLVD-YDSGRMIESDVYKKMIEMEN 607
               + L  E   L  K  ELE   EK     + +L L D ++  + +   + +K+  +E 
Sbjct: 1899 VRQIELVSE--RLRDKETELESIREKAYKEQSARLRLQDQFEDEKRVTKKLREKLETLEK 1956

Query: 608  LAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQ 667
            +       + LLE+    L ++L    Q+   +  K A+  Q + D++ S +K+ +++  
Sbjct: 1957 INAEYRSHVKLLEAD--TLRKDLTKKDQEIRRLRIK-AETLQTEIDRLHSLLKNGNMKTG 2013

Query: 668  IDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKM 727
                    +E   V   + L+KE+    +++ + +   +  + +   ++   +   LEK 
Sbjct: 2014 PTENEDWDREKQQV-STILLEKEERDRLLREKDVEVYALKERAEEMSKDRDRVRIALEKT 2072

Query: 728  SAEKISELLAKINHEEQSKIQTQFGIDAKIQE------RDLYIENI-ESELSKYKSRICR 780
             A  I     ++ H+E  + QT  G D  + +      +  YIE+  E ++++    +CR
Sbjct: 2073 EAMLI-YYKERLGHQEHKRKQT--GGDISLMQIVYFLFQTQYIEHASEIQVNRECLVLCR 2129

Query: 781  L--EESIAVMEDRRYSLERKADQLGSYLQ--EKQKAYSEYTIQEDELVNRLAVLMDHDRV 836
            +   +  ++   +R   ++    L  Y    + +K  ++    E  +  RL+ +      
Sbjct: 2130 VCSNQQASMGSCKRSFYKQHRLTLWPYHPPGDLEKVSADELDTESAVHGRLSAMQQAVAQ 2189

Query: 837  VEKQLLEIEHENKELQKKNQILLEENQNLQISLSDM 872
            +E Q   +E +N  L+KK + L  E Q+L+ +L+ +
Sbjct: 2190 LEVQQNLLEKKNSHLEKKIERLRTERQHLRETLTQL 2225


>UniRef50_O76329 Cluster: Interaptin; n=2; Dictyostelium
            discoideum|Rep: Interaptin - Dictyostelium discoideum
            (Slime mold)
          Length = 1738

 Score =  147 bits (357), Expect = 2e-33
 Identities = 242/1168 (20%), Positives = 524/1168 (44%), Gaps = 123/1168 (10%)

Query: 471  NTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAE-EQITQLN-----DEIDAANK 524
            NT  + E ++V E++ +++ +  K V V+ ++E  K  E E+I ++      D+I+    
Sbjct: 367  NTIIIAEESRVIEKIVEKIIEVEKIVEVEKIVEVEKIVEVEKIVEVEKIVKVDDIEKLTN 426

Query: 525  NMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLH 584
               ++    +   ++  K ++   ++ + + ++V  + +L  +    +EL E+ G L   
Sbjct: 427  LQDQLTEQQQQYQEKSLKLVNLELELQEKSNQLVDKSNQLSTMQATNSELMEKIGGLMND 486

Query: 585  LVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKL 644
            L D  +  + E D     +++E+  E  LK              + + LQ +Y    ++ 
Sbjct: 487  LTDIPTQDIKEKDEIIANLKIES--EKNLKCFQ----------DDFNALQSRYSLTIEQT 534

Query: 645  ADISQLQSDQVCSEIKSVHLEEQIDALSASKKELA---LVIENLKLDKEQLYGTIKDLEN 701
            + + Q +  Q+ +E++    ++ I+  ++S + LA    VI+ L  +K+ +   ++D ++
Sbjct: 535  SQL-QDRIKQLINELQERD-DKFIEFTNSSNQSLADNQRVIDQLTNEKQSITLQLQDQQD 592

Query: 702  DKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERD 761
             KE      + +  E   L  +++ ++   I E   K N+ +Q +  TQ  ++   QE  
Sbjct: 593  IKE------KEFQFEKQQLLSQIDSITTN-IQEYQDKFNNLQQ-EFNTQQTLNQ--QETH 642

Query: 762  LYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQED 821
               + +    + Y  +  +L+  I   +D +   E+   QL    +E +K  ++   Q+D
Sbjct: 643  RLTQQLYQINTDYNEKQTQLQSEI---KDNQTINEQLNKQLSEKDKEIEKLSNQQEQQQD 699

Query: 822  ELVNRLAV-LMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALV 880
            E +N L + + + D ++E+   ++  EN +L  K Q LL E +N ++         N+  
Sbjct: 700  EKINNLLLEIKEKDCLIERINQQLL-ENIDLNSKYQQLLLEFENFKL---------NSSK 749

Query: 881  EKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAI 940
            EK N+ +  +S+  +   QL D +   ++     +    Q K++        + Q++S I
Sbjct: 750  EKENQLNELQSKQDERFNQLNDEKLEKEKQLQSIEDEFNQYKQQQLSSNSNIDQQLQSTI 809

Query: 941  RDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQ--KQQT 998
             +   L E+ E N   + + E QLQ+ +   + LN   ++ ++  LEL++K ++  +Q+ 
Sbjct: 810  IELSELKEQKELNDSKLIEKEKQLQQLQQEFDQLNEKNQKDHQDQLELLEKQLKQLQQEY 869

Query: 999  QSPDYTEQYI-NEINKLNAL----LKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQF 1053
               + T Q I N++N+ N +    L +K++E++ L  ++N  Q+  +       SK    
Sbjct: 870  DQLNETNQSIENQLNQQNLINKENLNEKEQELLKLQNQLNQ-QIEKIQFDQQEFSKQNSI 928

Query: 1054 TTKLENMEEE----MQRVSKQLLDSKQHNEELQILVREQDDQIKELKETK-LTFEMN--I 1106
              +L N + E    +Q+   QL    + N+E     ++++D I++  + K +  E+N  I
Sbjct: 929  NIELVNEKNEKLIQLQQDYDQLKQQNRSNDE-----KDENDLIEKENQLKSIQNELNQLI 983

Query: 1107 PKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNT 1166
             K E       ++  S     ++            L+ Q  E+  Q+ + L E+  +LN 
Sbjct: 984  EKNESDHKEQQLKQQS-----IENDLIEKENQIQQLQSQLNEQRQQQSNQLSEKDQQLNQ 1038

Query: 1167 ELQECYTKIIQLE-TLNTELTGHDVVNQE-QINQLKSKLEQLNTENDNLLSTVAELRSSI 1224
             +++   +  Q E  L  +   +D+  +E QI QL+S+L +   +  N LS   E    +
Sbjct: 1039 LIEK--NQFDQKEQQLKQQSIENDLFEKENQIQQLQSQLNEQRQQQSNQLS---EKDQQL 1093

Query: 1225 SSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETN 1284
            +  +++   +  E   Q L Q+  +    E E ++Q    +   ++ L   QS    + +
Sbjct: 1094 NQLIEKNESDQKE---QQLKQQSIENDLIEKENQIQQLQLQLNEQRQL---QSEVSIDND 1147

Query: 1285 KIVTME-QVTSLQN---KLQD-KEEHLRNLQEKYADVINQIEILRSEIEDEK----VAFX 1335
            KI+ +E Q+   Q+   KL D K++  + LQ+K  +  +Q+++  ++ +++K    +   
Sbjct: 1148 KILELEKQLKQCQSDLLKLNDEKQQQDKQLQDKQIE-FDQLQLTFNQFKNDKDSQFIQLQ 1206

Query: 1336 XXXXXXXXXXXXXXXDLRTENQ-SYKQMQE--QSILNINEENAQLKKSSXXXXXXXXXXX 1392
                            L+ ENQ   KQ+ E  + + +I  EN + +K             
Sbjct: 1207 DDQKQQLQSIQQDLNQLKQENQEKEKQLSEKDEKLQSIQFENQEKEKQLSEKDEKLQSIQ 1266

Query: 1393 XRVNDAEAKVLELTHQLELKD----------SEIYQKTHEYTITLTQRNDEFENVRQQLV 1442
              +N    +  E   Q   KD          +++ Q+  E    L++++++ ++++Q L 
Sbjct: 1267 QNLNQLNDENQEKVKQFSEKDEKLQSIQQDLNQLKQENQEKEKQLSEKDEKLQSIQQDLN 1326

Query: 1443 EY-EKRIEDLTYEKESELAILRLKMHENANHYETM--------QKESEIERVKLIEELNV 1493
            +  + +I+     KE E  +L+L+   N    + +        +KE++++++K   E+N 
Sbjct: 1327 QLNDDQIKKNEKLKEKEEQLLKLQQDFNDQQSQQLKQLEEKLSEKENQLQQLKQENEIN- 1385

Query: 1494 KITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSK 1553
                 ++  +Q  E+ + L++++ K  + +    N E EI  L  EI  L+       S+
Sbjct: 1386 ----QLNQQQQSNEIIQQLKDQLLKQQQQEQQENNNEKEIERLIQEIEQLKQQQEIDQSE 1441

Query: 1554 IQKHVSFASDTKQGRDEQLDNTMNKELL 1581
            +  +      T Q   +QL +  +K+ L
Sbjct: 1442 L-SNKEIKIQTTQQEFDQLSHNRSKDQL 1468



 Score =  142 bits (344), Expect = 7e-32
 Identities = 237/1213 (19%), Positives = 528/1213 (43%), Gaps = 109/1213 (8%)

Query: 144  VTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKI----NEKDQIIEAKNKATTXXXXX 199
            + +L   ++EK N L     ++  M+ T  +L EKI    N+   I     K        
Sbjct: 445  LVNLELELQEKSNQLVDKSNQLSTMQATNSELMEKIGGLMNDLTDIPTQDIKEKDEIIAN 504

Query: 200  XXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVR-ISSLEEANK 258
                        +D    +       I   ++ +D  ++L+ +++ +D + I     +N+
Sbjct: 505  LKIESEKNLKCFQDDFNALQSRYSLTIEQTSQLQDRIKQLINELQERDDKFIEFTNSSNQ 564

Query: 259  LL---EAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEK-G 314
             L   +    +++ E   +  +L+                    I+       E ++K  
Sbjct: 565  SLADNQRVIDQLTNEKQSITLQLQDQQDIKEKEFQFEKQQLLSQIDSITTNIQEYQDKFN 624

Query: 315  SLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKS 374
            +L+    T+ T   +    L  Q+ Q N +   K   + +E         K +  I+ + 
Sbjct: 625  NLQQEFNTQQTLNQQETHRLTQQLYQINTDYNEKQTQLQSEI--------KDNQTINEQL 676

Query: 375  GRNTASKMKSPWSQLSSETLNQDTDKKINK--NEIAKLEMVIQSLNKDLVDKEYVISEKD 432
             +  + K K    +LS++   Q  D+KIN    EI + + +I+ +N+ L++   + S+  
Sbjct: 677  NKQLSEKDKE-IEKLSNQQ-EQQQDEKINNLLLEIKEKDCLIERINQQLLENIDLNSK-- 732

Query: 433  TXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDE 492
                              QL LE     E   L         +NE+   Q++   +LNDE
Sbjct: 733  ----------------YQQLLLE----FENFKLNSSKEKENQLNELQSKQDERFNQLNDE 772

Query: 493  IKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTID-NFSKVS 551
              +       ++L+S E++  Q   +  ++N N+ +   +  ++L ++++  + N SK+ 
Sbjct: 773  KLEKE-----KQLQSIEDEFNQYKQQQLSSNSNIDQQLQSTIIELSELKEQKELNDSKLI 827

Query: 552  DSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAET 611
            +  K++ +L +E   L++K  +  ++    QL L++    ++ +   Y ++ E     E 
Sbjct: 828  EKEKQLQQLQQEFDQLNEKNQKDHQD----QLELLEKQLKQLQQE--YDQLNETNQSIEN 881

Query: 612  RLKAISLLESQKF-DLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDA 670
            +L   +L+  +   +  QEL  LQ + ++  +K+    Q  S Q    I+ V+  E+ + 
Sbjct: 882  QLNQQNLINKENLNEKEQELLKLQNQLNQQIEKIQFDQQEFSKQNSINIELVN--EKNEK 939

Query: 671  LSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAE 730
            L   +++   + +  + + E+    + + EN  + I N+L   I++N +   K +++  +
Sbjct: 940  LIQLQQDYDQLKQQNRSNDEKDENDLIEKENQLKSIQNELNQLIEKN-ESDHKEQQLKQQ 998

Query: 731  KI-SELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESI--AV 787
             I ++L+ K N  +Q  +Q+Q     + Q   L  ++ +      K++  + E+ +    
Sbjct: 999  SIENDLIEKENQIQQ--LQSQLNEQRQQQSNQLSEKDQQLNQLIEKNQFDQKEQQLKQQS 1056

Query: 788  MEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHE 847
            +E+  +  E +  QL S L E+++  S    ++D+ +N+L    + D+  E+QL +   E
Sbjct: 1057 IENDLFEKENQIQQLQSQLNEQRQQQSNQLSEKDQQLNQLIEKNESDQ-KEQQLKQQSIE 1115

Query: 848  NKELQKKNQI-----LLEENQNLQISLSDMQQHYNALVE--KANRTDLAESESTKYQ--T 898
            N  ++K+NQI      L E + LQ  +S        L +  K  ++DL +    K Q   
Sbjct: 1116 NDLIEKENQIQQLQLQLNEQRQLQSEVSIDNDKILELEKQLKQCQSDLLKLNDEKQQQDK 1175

Query: 899  QLRD-------LESNLKRITHEHQTLIVQ----KKKEIEDLEIEFNTQIESAIRDKKVLN 947
            QL+D       L+    +  ++  +  +Q    +K++++ ++ + N   +     +K L+
Sbjct: 1176 QLQDKQIEFDQLQLTFNQFKNDKDSQFIQLQDDQKQQLQSIQQDLNQLKQENQEKEKQLS 1235

Query: 948  EKYEK--NIEYVTQ-LEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYT 1004
            EK EK  +I++  Q  E QL E    ++++  N+ +LN  N E +     KQ ++  +  
Sbjct: 1236 EKDEKLQSIQFENQEKEKQLSEKDEKLQSIQQNLNQLNDENQEKV-----KQFSEKDEKL 1290

Query: 1005 EQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEM 1064
            +    ++N+L    ++K++++   ++K+ + Q     +  D   K      KL+  EE++
Sbjct: 1291 QSIQQDLNQLKQENQEKEKQLSEKDEKLQSIQQDLNQLNDDQIKK----NEKLKEKEEQL 1346

Query: 1065 QRVSKQLLDSK-QHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSD 1123
             ++ +   D + Q  ++L+  + E+++Q+++LK+     ++N  +    II    + +  
Sbjct: 1347 LKLQQDFNDQQSQQLKQLEEKLSEKENQLQQLKQENEINQLNQQQQSNEIIQQLKDQLLK 1406

Query: 1124 DANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNT 1183
                                +QE E+  Q++ + Q + +    ++Q    +  QL    +
Sbjct: 1407 QQQQEQQENNNEKEIERL--IQEIEQLKQQQEIDQSELSNKEIKIQTTQQEFDQLSHNRS 1464

Query: 1184 ELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGF---EIAELWK 1240
            +    D ++ +Q+ Q   +L+Q   + D+    V + R ++   ++Q      ++ +L K
Sbjct: 1465 K----DQLHLQQLQQELDQLKQSFDDQDHQFKKVIDERYNLQLQLEQSTLSNNQLDQLLK 1520

Query: 1241 QHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTME-QVTSLQNKL 1299
            + L   E D  + +  +   LS   S  +  L + +    E  N I T+E ++T   + L
Sbjct: 1521 EKLKPLELDSNEKQKTIDDLLSNI-SNLQISLQNDKDLISERNNSIKTLESRITQQLSLL 1579

Query: 1300 QDKEEHLRNLQEK 1312
             +K+  +++LQ++
Sbjct: 1580 DEKDNLIKDLQQQ 1592



 Score =  132 bits (320), Expect = 6e-29
 Identities = 215/1167 (18%), Positives = 508/1167 (43%), Gaps = 87/1167 (7%)

Query: 169  ETTILD-LQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIA 227
            E+ +++ + EKI E ++I+E +                       D  +++T +Q+    
Sbjct: 374  ESRVIEKIVEKIIEVEKIVEVEKIVEVEKIVEVEKIVEVEKIVKVDDIEKLTNLQDQLTE 433

Query: 228  MEAEWKDEKQRLLK-DIESKDVRISSLEEANKL--LEAARFEISLEHSKLAQELEQXXXX 284
             + +++++  +L+  ++E ++     ++++N+L  ++A   E+  +   L  +L      
Sbjct: 434  QQQQYQEKSLKLVNLELELQEKSNQLVDKSNQLSTMQATNSELMEKIGGLMNDLTDIPTQ 493

Query: 285  XXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKE 344
                      +A   IE     K   ++  +L+      + +  +L + +   I +  + 
Sbjct: 494  DIKEKDEI--IANLKIESEKNLKCFQDDFNALQSRYSLTIEQTSQLQDRIKQLINELQER 551

Query: 345  LENKLATMGTESKAVSSPSKKGSPLISRKSG----RNTASKMKSPWSQLSSETLNQDTDK 400
             +  +    + +++++   +    L + K            +K    Q   + L    D 
Sbjct: 552  DDKFIEFTNSSNQSLADNQRVIDQLTNEKQSITLQLQDQQDIKEKEFQFEKQQLLSQIDS 611

Query: 401  KINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHM 460
             I  N I + +    +L ++  + +  +++++T            D    Q QL  Q  +
Sbjct: 612  -ITTN-IQEYQDKFNNLQQEF-NTQQTLNQQETHRLTQQLYQINTDYNEKQTQL--QSEI 666

Query: 461  EGPSLIHVGTN---TEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLND 517
            +    I+   N   +E   EI K+  Q +Q+ +++I ++ + ++ EK    E    QL +
Sbjct: 667  KDNQTINEQLNKQLSEKDKEIEKLSNQQEQQQDEKINNL-LLEIKEKDCLIERINQQLLE 725

Query: 518  EIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKV-SDSNKEIVRLTEELHHLSQKVAELEE 576
             ID  +K    +      KL   ++  +  +++ S  ++   +L +E     +++  +E+
Sbjct: 726  NIDLNSKYQQLLLEFENFKLNSSKEKENQLNELQSKQDERFNQLNDEKLEKEKQLQSIED 785

Query: 577  EKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQK 636
            E    +   +  +S   I+  +   +IE+  L E +     L +S+  +  ++L  LQQ+
Sbjct: 786  EFNQYKQQQLSSNSN--IDQQLQSTIIELSELKEQK----ELNDSKLIEKEKQLQQLQQE 839

Query: 637  YDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTI 696
            +D++ +K     Q Q + +  ++K   L+++ D L+ + +     IEN +L+++ L    
Sbjct: 840  FDQLNEKNQKDHQDQLELLEKQLKQ--LQQEYDQLNETNQS----IEN-QLNQQNLIN-- 890

Query: 697  KDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAK 756
            K+  N+KE  + KLQN + + ++     ++  +++ S  +  +N + +  IQ Q   D  
Sbjct: 891  KENLNEKEQELLKLQNQLNQQIEKIQFDQQEFSKQNSINIELVNEKNEKLIQLQQDYDQL 950

Query: 757  IQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEY 816
             Q+     E  E++L + ++++  ++  +  + ++  S + K  QL      KQ++    
Sbjct: 951  KQQNRSNDEKDENDLIEKENQLKSIQNELNQLIEKNES-DHKEQQL------KQQSIEND 1003

Query: 817  TIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHY 876
             I+++  + +L   ++  R  ++Q  ++  ++++L   NQ L+E+NQ          Q  
Sbjct: 1004 LIEKENQIQQLQSQLNEQR--QQQSNQLSEKDQQL---NQ-LIEKNQ--------FDQKE 1049

Query: 877  NALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDL-EIEFNTQ 935
              L +++   DL E E+     Q++ L+S L     +    + +K +++  L E   + Q
Sbjct: 1050 QQLKQQSIENDLFEKEN-----QIQQLQSQLNEQRQQQSNQLSEKDQQLNQLIEKNESDQ 1104

Query: 936  IESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQK 995
             E  ++ + + N+  EK  + + QL+ QL E +     L   V   N   LEL +K +++
Sbjct: 1105 KEQQLKQQSIENDLIEKENQ-IQQLQLQLNEQRQ----LQSEVSIDNDKILEL-EKQLKQ 1158

Query: 996  QQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTT 1055
             Q+      ++   +  +L     + D+  +  NQ  N+    ++ +  D + +L     
Sbjct: 1159 CQSDLLKLNDEKQQQDKQLQDKQIEFDQLQLTFNQFKNDKDSQFIQLQDDQKQQLQSIQQ 1218

Query: 1056 KLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEG---- 1111
             L  +++E Q   KQL +  +  + +Q   +E++ Q+ E  E   + + N+ +       
Sbjct: 1219 DLNQLKQENQEKEKQLSEKDEKLQSIQFENQEKEKQLSEKDEKLQSIQQNLNQLNDENQE 1278

Query: 1112 --MIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEE--EEFIQERSVLQEQSAKLNTE 1167
                 S   E +     +++            L  ++E  +   Q+ + L +   K N +
Sbjct: 1279 KVKQFSEKDEKLQSIQQDLNQLKQENQEKEKQLSEKDEKLQSIQQDLNQLNDDQIKKNEK 1338

Query: 1168 LQECYTKIIQLET-LNTELTGHDVVNQEQINQLKSKLEQLNTEND-NLLSTVAELRSSIS 1225
            L+E   ++++L+   N + +      +E++++ +++L+QL  EN+ N L+   +    I 
Sbjct: 1339 LKEKEEQLLKLQQDFNDQQSQQLKQLEEKLSEKENQLQQLKQENEINQLNQQQQSNEIIQ 1398

Query: 1226 SAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNK 1285
               DQ       L KQ   +++ +  + E E  +Q    + K +Q +D  + S +E   +
Sbjct: 1399 QLKDQ-------LLKQQQQEQQENNNEKEIERLIQ-EIEQLKQQQEIDQSELSNKEIKIQ 1450

Query: 1286 IVTMEQVTSLQNKLQDKEEHLRNLQEK 1312
              T ++   L +     + HL+ LQ++
Sbjct: 1451 -TTQQEFDQLSHNRSKDQLHLQQLQQE 1476



 Score =  116 bits (278), Expect = 7e-24
 Identities = 205/1011 (20%), Positives = 446/1011 (44%), Gaps = 86/1011 (8%)

Query: 147  LSNTIKEKDNALSVLQVKMKIMETT-ILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXX 205
            L+  + EKD  +  L  + +  +   I +L  +I EKD +IE  N+              
Sbjct: 676  LNKQLSEKDKEIEKLSNQQEQQQDEKINNLLLEIKEKDCLIERINQQLLENIDLNSKYQQ 735

Query: 206  XXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIE-SKDVRISSLE-EANKLLE-- 261
                  E+ K   +K +EN +      +DE+   L D +  K+ ++ S+E E N+  +  
Sbjct: 736  LLLEF-ENFKLNSSKEKENQLNELQSKQDERFNQLNDEKLEKEKQLQSIEDEFNQYKQQQ 794

Query: 262  -AARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIAN 320
             ++   I  +      EL +                KQ ++   +E  ++ EK   +  +
Sbjct: 795  LSSNSNIDQQLQSTIIELSELKEQKELNDSKLIEKEKQ-LQQLQQEFDQLNEKNQKDHQD 853

Query: 321  MTELTKK-IELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTA 379
              EL +K ++ L+    Q+ +TN+ +EN+L      +K   + ++K   L+  ++  N  
Sbjct: 854  QLELLEKQLKQLQQEYDQLNETNQSIENQLNQQNLINK--ENLNEKEQELLKLQNQLNQQ 911

Query: 380  SKMKSPWSQLSSETLNQDTDKKIN-KNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXX 438
             + K  + Q      N    + +N KNE  KL  + Q  ++ L  +     EKD      
Sbjct: 912  IE-KIQFDQQEFSKQNSINIELVNEKNE--KLIQLQQDYDQ-LKQQNRSNDEKDENDLIE 967

Query: 439  XXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNV 498
                  K+  +  +Q E  Q +E         N  D  E    Q+ ++ +L +  K+  +
Sbjct: 968  ------KENQLKSIQNELNQLIE--------KNESDHKEQQLKQQSIENDLIE--KENQI 1011

Query: 499  KDLIEKL-KSAEEQITQLNDEIDAANKNMIKVKSNHK-LKLKQMQKTIDNFSKVSDSNKE 556
            + L  +L +  ++Q  QL+++    N+ + K + + K  +LKQ     D F K +   + 
Sbjct: 1012 QQLQSQLNEQRQQQSNQLSEKDQQLNQLIEKNQFDQKEQQLKQQSIENDLFEKENQIQQL 1071

Query: 557  IVRLTEELHHLSQKVAELEEEKGNL-QLHLVDYDSGRMIESDVYKKMIEMENLAETRLKA 615
              +L E+    S +++E +++   L + +  D    ++ +  +   +IE EN    +++ 
Sbjct: 1072 QSQLNEQRQQQSNQLSEKDQQLNQLIEKNESDQKEQQLKQQSIENDLIEKEN----QIQQ 1127

Query: 616  ISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASK 675
            + L  +++  L  E+ I   K  E+E +L    Q QSD +    +    ++Q+       
Sbjct: 1128 LQLQLNEQRQLQSEVSIDNDKILELEKQL---KQCQSDLLKLNDEKQQQDKQLQDKQIEF 1184

Query: 676  KELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISEL 735
             +L L     K DK+  +     L++D++  +  +Q  + +      + EK  +EK  E 
Sbjct: 1185 DQLQLTFNQFKNDKDSQF---IQLQDDQKQQLQSIQQDLNQLKQENQEKEKQLSEK-DEK 1240

Query: 736  LAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSL 795
            L  I  E Q K       + ++ E+D  +++I+  L++         +  +  +++  S+
Sbjct: 1241 LQSIQFENQEK-------EKQLSEKDEKLQSIQQNLNQLNDENQEKVKQFSEKDEKLQSI 1293

Query: 796  ERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKN 855
            ++  +QL    QEK+K  SE    +DE +   ++  D +++ + Q+     +N++L++K 
Sbjct: 1294 QQDLNQLKQENQEKEKQLSE----KDEKLQ--SIQQDLNQLNDDQI----KKNEKLKEKE 1343

Query: 856  QILLEENQNLQISLS-DMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEH 914
            + LL+  Q+     S  ++Q    L EK N+    + E+     QL   + + + I    
Sbjct: 1344 EQLLKLQQDFNDQQSQQLKQLEEKLSEKENQLQQLKQENE--INQLNQQQQSNEIIQQLK 1401

Query: 915  QTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENL 974
              L+ Q+++E ++   E   +IE  I++ + L ++ E +   ++  E ++Q  +   + L
Sbjct: 1402 DQLLKQQQQEQQENNNE--KEIERLIQEIEQLKQQQEIDQSELSNKEIKIQTTQQEFDQL 1459

Query: 975  NMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQ--KI 1032
            + N    ++++L+ + + + + +    D   Q+   I++   L  Q ++  ++ NQ  ++
Sbjct: 1460 SHN-RSKDQLHLQQLQQELDQLKQSFDDQDHQFKKVIDERYNLQLQLEQSTLSNNQLDQL 1518

Query: 1033 NNAQVSYMSMVSDYESK-LAQFTTKLENMEEEMQRVSKQLLDSKQHN---EELQI----- 1083
               ++  + + S+ + K +    + + N++  +Q   K L+  + ++    E +I     
Sbjct: 1519 LKEKLKPLELDSNEKQKTIDDLLSNISNLQISLQN-DKDLISERNNSIKTLESRITQQLS 1577

Query: 1084 LVREQDDQIKELKETKLTFEM-----NIPKTEGMIISSTIEPMSDDANNVD 1129
            L+ E+D+ IK+L++ K   +      + P +   ++SST  P     N ++
Sbjct: 1578 LLDEKDNLIKDLQQQKQQQQQPPTASSSPSSSPSLLSSTPTPKPQRPNQIE 1628



 Score = 87.0 bits (206), Expect = 4e-15
 Identities = 149/760 (19%), Positives = 334/760 (43%), Gaps = 75/760 (9%)

Query: 147  LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINE-KDQIIEAKNKATTXXXXXXXXXXX 205
            L+  I++ ++     Q+K + +E  +++ + +I + + Q+ E + + +            
Sbjct: 979  LNQLIEKNESDHKEQQLKQQSIENDLIEKENQIQQLQSQLNEQRQQQSNQLSEKDQQLNQ 1038

Query: 206  XXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEA-AR 264
                   D K+Q  K Q    ++E +   EK+  ++ ++S+ +     +++N+L E   +
Sbjct: 1039 LIEKNQFDQKEQQLKQQ----SIENDLF-EKENQIQQLQSQ-LNEQRQQQSNQLSEKDQQ 1092

Query: 265  FEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTEL 324
                +E ++  Q+ +Q                 Q ++    E+ +++ + S++   + EL
Sbjct: 1093 LNQLIEKNESDQKEQQLKQQSIENDLIEKENQIQQLQLQLNEQRQLQSEVSIDNDKILEL 1152

Query: 325  TKKIELLEH----LNCQIRQTNKELENKLATMGTESKAVSS-PSKKGSPLISRKSG-RNT 378
             K+++  +     LN + +Q +K+L++K           +   + K S  I  +   +  
Sbjct: 1153 EKQLKQCQSDLLKLNDEKQQQDKQLQDKQIEFDQLQLTFNQFKNDKDSQFIQLQDDQKQQ 1212

Query: 379  ASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXX 438
               ++   +QL  E  NQ+ +K++++ +  KL    QS+  +  +KE  +SEKD      
Sbjct: 1213 LQSIQQDLNQLKQE--NQEKEKQLSEKD-EKL----QSIQFENQEKEKQLSEKDEKLQSI 1265

Query: 439  XXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNV 498
                      + QL  E+Q+ ++           E +  I +   QLKQE  ++ K ++ 
Sbjct: 1266 QQN-------LNQLNDENQEKVK-----QFSEKDEKLQSIQQDLNQLKQENQEKEKQLSE 1313

Query: 499  KDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQ--KTIDNFSKVSDSNKE 556
            KD  EKL+S ++ + QLND+         ++K N KLK K+ Q  K   +F+     +++
Sbjct: 1314 KD--EKLQSIQQDLNQLNDD---------QIKKNEKLKEKEEQLLKLQQDFN--DQQSQQ 1360

Query: 557  IVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIES--DVYKKMIEMENLAETRLK 614
            + +L E+L     ++ +L++E    QL+     S  +I+   D   K  + E       K
Sbjct: 1361 LKQLEEKLSEKENQLQQLKQENEINQLNQ-QQQSNEIIQQLKDQLLKQQQQEQQENNNEK 1419

Query: 615  AISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSAS 674
             I  L       +QE+  L+Q+ +       D S+L +     EIK    +++ D LS +
Sbjct: 1420 EIERL-------IQEIEQLKQQQE------IDQSELSN----KEIKIQTTQQEFDQLSHN 1462

Query: 675  KKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISE 734
            + +  L ++ L+ + +QL  +  D ++  + ++++  N +Q  ++ +        + + E
Sbjct: 1463 RSKDQLHLQQLQQELDQLKQSFDDQDHQFKKVIDERYN-LQLQLEQSTLSNNQLDQLLKE 1521

Query: 735  LLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYS 794
             L  +  +   K +T   + + I    + ++N +  +S+  + I  LE  I     ++ S
Sbjct: 1522 KLKPLELDSNEKQKTIDDLLSNISNLQISLQNDKDLISERNNSIKTLESRIT----QQLS 1577

Query: 795  LERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHD--RVVEKQLLEIEHENKELQ 852
            L  + D L   LQ++++   +         +  ++L      +      +EI+    E+ 
Sbjct: 1578 LLDEKDNLIKDLQQQKQQQQQPPTASSSPSSSPSLLSSTPTPKPQRPNQIEIDRLVNEIV 1637

Query: 853  KKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESE 892
             +NQ L+ +N+     L +     N+++ + +  D  +S+
Sbjct: 1638 NRNQDLIRKNKTKFYKLENGDYIVNSIIYRLSLDDDNDSD 1677



 Score = 77.8 bits (183), Expect = 2e-12
 Identities = 153/736 (20%), Positives = 284/736 (38%), Gaps = 43/736 (5%)

Query: 859  LEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLI 918
            L  N N+  SLS           K N   L++S S + Q Q +  + NL        ++ 
Sbjct: 255  LNNNNNISPSLSSSSSSLLNTPNKRNSIQLSKSTSFEQQNQ-QQQQQNLLSPNSYRNSIS 313

Query: 919  VQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNV 978
              K    E  +   +++  S I      +     N+   T  E    E  N   N  + +
Sbjct: 314  FSKSPSFEGSQSTGSSRSISPISSPIKNSTTGNSNLSKSTSFEK--IEASNTTNNNTIII 371

Query: 979  EELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKD-EEIIALN--QKINNA 1035
             E +++  ++++K ++ ++        + I E+ K+  + K  + E+I+ ++  +K+ N 
Sbjct: 372  AEESRVIEKIVEKIIEVEKI----VEVEKIVEVEKIVEVEKIVEVEKIVKVDDIEKLTNL 427

Query: 1036 QVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKEL 1095
            Q         Y+ K    + KL N+E E+Q  S QL+D       +Q    E  ++I  L
Sbjct: 428  QDQLTEQQQQYQEK----SLKLVNLELELQEKSNQLVDKSNQLSTMQATNSELMEKIGGL 483

Query: 1096 KETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERS 1155
                        K +  II++      +   N+               +      I++ S
Sbjct: 484  MNDLTDIPTQDIKEKDEIIANL---KIESEKNLKCFQDDFNALQSRYSLT-----IEQTS 535

Query: 1156 VLQEQSAKLNTELQECYTKIIQL-ETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLL 1214
             LQ++  +L  ELQE   K I+   + N  L  +  V  +  N+ +S   QL  + D   
Sbjct: 536  QLQDRIKQLINELQERDDKFIEFTNSSNQSLADNQRVIDQLTNEKQSITLQLQDQQDIKE 595

Query: 1215 STVAELRSSISSAVDQRGFEIAELW-KQHLAQREADFQKT-----EHELRVQLSAFESKY 1268
                  +  + S +D     I E   K +  Q+E + Q+T      H L  QL    + Y
Sbjct: 596  KEFQFEKQQLLSQIDSITTNIQEYQDKFNNLQQEFNTQQTLNQQETHRLTQQLYQINTDY 655

Query: 1269 EQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKE-EHLRNLQEKYAD-VINQIEILRSE 1326
             +     Q+  Q E     T+ +  + Q   +DKE E L N QE+  D  IN + +L  +
Sbjct: 656  NE----KQTQLQSEIKDNQTINEQLNKQLSEKDKEIEKLSNQQEQQQDEKINNL-LLEIK 710

Query: 1327 IEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILN-INEENAQLKKSSXXXX 1385
             +D  +                   L  E +++K    +   N +NE  ++  +      
Sbjct: 711  EKDCLIERINQQLLENIDLNSKYQQLLLEFENFKLNSSKEKENQLNELQSKQDERFNQLN 770

Query: 1386 XXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYE 1445
                    ++   E +  +   Q    +S I Q+     I L++  ++ E    +L+E E
Sbjct: 771  DEKLEKEKQLQSIEDEFNQYKQQQLSSNSNIDQQLQSTIIELSELKEQKELNDSKLIEKE 830

Query: 1446 KRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQV 1505
            K+++ L  E + +L     K H++       Q +   +    + E N  I     LN+Q 
Sbjct: 831  KQLQQLQQEFD-QLNEKNQKDHQDQLELLEKQLKQLQQEYDQLNETNQSIEN--QLNQQN 887

Query: 1506 AELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRAS--SSKIQKHVSFASD 1563
                + L E+  +  ++Q  L NQ+IE +  + +  + QN +     + K +K +    D
Sbjct: 888  LINKENLNEKEQELLKLQNQL-NQQIEKIQFDQQEFSKQNSINIELVNEKNEKLIQLQQD 946

Query: 1564 TKQGRDEQLDNTMNKE 1579
              Q + +   N    E
Sbjct: 947  YDQLKQQNRSNDEKDE 962



 Score = 41.1 bits (92), Expect = 0.25
 Identities = 76/399 (19%), Positives = 160/399 (40%), Gaps = 21/399 (5%)

Query: 143  DVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXX 202
            D+  L    +EK+  LS    K++ ++    + +++++EKD+ +++  +           
Sbjct: 1219 DLNQLKQENQEKEKQLSEKDEKLQSIQFENQEKEKQLSEKDEKLQSIQQ--NLNQLNDEN 1276

Query: 203  XXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEA 262
                     +D K Q  +   N      + K E Q   K +  KD ++ S+++    L  
Sbjct: 1277 QEKVKQFSEKDEKLQSIQQDLN------QLKQENQEKEKQLSEKDEKLQSIQQDLNQLND 1330

Query: 263  ARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEE-KGSLEIANM 321
             + +   ++ KL ++ EQ                KQ  E   E++ ++++ K   EI  +
Sbjct: 1331 DQIK---KNEKLKEKEEQLLKLQQDFNDQQSQQLKQLEEKLSEKENQLQQLKQENEINQL 1387

Query: 322  TELTKKIELLEHLNCQ-IRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTAS 380
             +  +  E+++ L  Q ++Q  +E +        E         K    I +    N   
Sbjct: 1388 NQQQQSNEIIQQLKDQLLKQQQQEQQENNNEKEIERLIQEIEQLKQQQEIDQSELSNKEI 1447

Query: 381  KMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXX 440
            K+++   +    + N+  D+   +    +L+ + QS +      + VI E+         
Sbjct: 1448 KIQTTQQEFDQLSHNRSKDQLHLQQLQQELDQLKQSFDDQDHQFKKVIDERYNLQLQLEQ 1507

Query: 441  XXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKD 500
                 + L  QL  E  + +E  S     T  + ++ I+ +Q  L+   ND  KD+ + +
Sbjct: 1508 STLSNNQL-DQLLKEKLKPLELDSNEKQKTIDDLLSNISNLQISLQ---ND--KDL-ISE 1560

Query: 501  LIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQ 539
                +K+ E +ITQ    +D  + N+IK     K + +Q
Sbjct: 1561 RNNSIKTLESRITQQLSLLDEKD-NLIKDLQQQKQQQQQ 1598


>UniRef50_A0DDW1 Cluster: Chromosome undetermined scaffold_47, whole
            genome shotgun sequence; n=1; Paramecium tetraurelia|Rep:
            Chromosome undetermined scaffold_47, whole genome shotgun
            sequence - Paramecium tetraurelia
          Length = 1279

 Score =  147 bits (357), Expect = 2e-33
 Identities = 229/1183 (19%), Positives = 509/1183 (43%), Gaps = 101/1183 (8%)

Query: 404  KNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGP 463
            K E   L   I+SL++ L D  Y+I    +            +    +  L   ++ +  
Sbjct: 150  KIENISLSNTIKSLSQQLSDARYIIQRLYSQVDLNQQQDTQDNNSTQENNLVFYEY-QNF 208

Query: 464  SLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLI-EKLKSAEEQITQ--LNDEID 520
             L  +    +   +  +++E+   ++  ++  +N K  I E L S+  QI    + +E+ 
Sbjct: 209  ILRQLNELEQQTLQSLELKEEKMLKIMKKLNKINRKQQIDEDLLSSARQIDSKTIINELK 268

Query: 521  AANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGN 580
               +N+++   N +++LKQ QK      K++ + +   +  E      Q +  LE+EK  
Sbjct: 269  QDKQNLLQKVKNLEIQLKQEQKKPSYEQKLNQAQQIEEQFNEFKKKHQQIIYNLEQEKST 328

Query: 581  L--QLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYD 638
               +  L+  ++ + I+  +  ++I + +  E R + I  L +Q  +  +     QQ   
Sbjct: 329  SLEKEQLIKKEAQQKIKK-LESQLIALMDELEGRDQIIESL-NQTINQNKNQSQKQQDVQ 386

Query: 639  EVEDKLADISQLQSD-QVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIK 697
            ++ +KL +  Q+Q D     ++   +    ++ L  SK E    ++ ++ D   L G   
Sbjct: 387  QLINKLKENEQIQQDLNQQIQLMKKNNNTILNELENSKVE----VQKIRKDYSTLQGQFD 442

Query: 698  DLENDKEDIMNKLQNYIQENMDLTDKLE---KMSAEKISELLAKINHEEQSKIQTQFG-I 753
              + +  +++ K+Q   Q+     D L    ++  EK+SE LA IN ++ +K+   +  +
Sbjct: 443  YTKQENTELIKKIQYVNQQKQQSIDSLNDQWQIHNEKLSEQLA-INEDKYAKLSINYNQL 501

Query: 754  DAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAY 813
              + Q+ +  ++  E EL      +   E+    +  +  +++  A Q   Y     K  
Sbjct: 502  SKQKQDLETQLKLKEKELESKLEELTEFEQLQLRVNKQNQTIQNLAQQNQQYEATLVKNI 561

Query: 814  SEYTIQEDELVNRLAVLMD------HDRVVEKQLLEIEHENKELQKKNQILLEENQNLQI 867
             E    E ++ + +  L D      + +++  ++++ + E  +L K+N  LL E   LQ 
Sbjct: 562  DEKKQFEKQIQDLMEKLKDLSQDNLNQQLLSDKIVKYQQEIDKLNKQNSRLLNEKNELQE 621

Query: 868  SLSDMQQHYNALVEKANRTD----LAESE-------STKYQTQLRDLESNLKRITHEHQT 916
            S+ + +   + L++   + +    LA  E        TKYQ +  DL   +  +T +++ 
Sbjct: 622  SIKNEKDKSDLLIQNLEKLEDQLALANQEIEEQTQKITKYQKENLDLLKQMDELTAKNKK 681

Query: 917  LIVQKKKEIEDLEIEFNTQI---ESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIEN 973
            L+ ++ +E E+       ++   E+ + + +  N   E+ IE +   E + Q+  + I N
Sbjct: 682  LLKEQNEEWEEQNNNLLQKLALSENNLLNLQQKNTNQERIIEKLQVFEIENQKKDDYILN 741

Query: 974  LNMNVEELNKMN-LELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKI 1032
            L   +++  ++N      + +   Q Q  D  ++    +N    L  +   E   L  K+
Sbjct: 742  LKQQLDDQGQINQFNQNTQEIVDLQNQLLDVNKEKEQLLNDNIQLQNEFGNEKQILENKV 801

Query: 1033 NNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQI 1092
            ++        +  YE++L Q+ T      +++++  +QL++ +   +E QI   +   Q+
Sbjct: 802  DDQS----KKLEQYENELQQYKTNQLQFNDKLKQAQRQLVELQSELQEEQIKSLQLQSQL 857

Query: 1093 KELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQ 1152
            + + E K + + N    +  I  S I P                       VQ++++   
Sbjct: 858  QSISENKSSLQQNQDLLD--IFESQISPRQQ-----ATVQQMTETISYTESVQQQDQL-- 908

Query: 1153 ERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDN 1212
               +L++Q  +L   +QE   +I Q+     E+     V  E++N  ++ + QLN EN  
Sbjct: 909  --HLLKQQIQQLQEIIQEKDLEINQVIQQKNEMESSLDVAIEKMNNQENLILQLNQENGK 966

Query: 1213 LLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLL 1272
            L   + E +S I+    ++     E+  Q L  +  D Q+       +L  +E+K ++  
Sbjct: 967  L---IEEQKSEINH--QKQKISSQEMVIQSLQSQIEDLQQ-------ELQGYENKQKEQE 1014

Query: 1273 DSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKV 1332
            D++Q        KI+   Q   L+  + +K++ +++L+E+    +N+I     +++++ V
Sbjct: 1015 DNIQ-------KKILEQNQEQQLKKLIAEKDQEIQSLREQ----LNKIHEQFDQLQNKSV 1063

Query: 1333 AFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXX 1392
                              D+  E ++ ++++++  L    EN  LK+             
Sbjct: 1064 LSNRSKRSFQVAKFDQFRDI-NEEENNEELEDEDDLKF--ENMILKEQ-------INKKE 1113

Query: 1393 XRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLT 1452
              +   E ++     Q    D+E  Q+T +    L  +N   E + Q++ + +K +E L 
Sbjct: 1114 DLIKQQEQQIKSFNEQ----DNEKSQQTEKEKQLLQNQN---ELLLQEIDKMQKEMEKLK 1166

Query: 1453 YEKESELAILRLKMHEN--ANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNK 1510
             E+   L    L+M+++  +N  +  Q + + ++ + + + N + ++    N+   ELN 
Sbjct: 1167 EEQRRMLEQFELQMNKSVISNRSKRSQNQIQYDQFQDLPDDNSQGSQDEDENE---ELNL 1223

Query: 1511 ALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSK 1553
             + ++  KT++ Q  ++N +  I  L +E  +LQ  +    +K
Sbjct: 1224 FVLQK--KTSDQQKQIQNLQETIQKLKEENNSLQEEINVLKNK 1264



 Score =  133 bits (322), Expect = 3e-29
 Identities = 202/1014 (19%), Positives = 443/1014 (43%), Gaps = 76/1014 (7%)

Query: 372  RKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEK 431
            ++  +N   K+K+   QL  E      ++K+N+ +  ++E       K      Y + ++
Sbjct: 268  KQDKQNLLQKVKNLEIQLKQEQKKPSYEQKLNQAQ--QIEEQFNEFKKKHQQIIYNLEQE 325

Query: 432  DTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAK-VQEQLKQELN 490
             +           K+ LI +   +  + +E   LI +    E  ++I + + + + Q  N
Sbjct: 326  KSTSLE-------KEQLIKKEAQQKIKKLES-QLIALMDELEGRDQIIESLNQTINQNKN 377

Query: 491  DEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKN---MIKVKSNHKLKLKQMQKTIDNF 547
               K  +V+ LI KLK  E+    LN +I    KN   ++    N K+++++++K     
Sbjct: 378  QSQKQQDVQQLINKLKENEQIQQDLNQQIQLMKKNNNTILNELENSKVEVQKIRKDYSTL 437

Query: 548  SKVSDSNK-EIVRLTEELHHLS-QKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKM-IE 604
                D  K E   L +++ +++ QK   ++      Q+H         I  D Y K+ I 
Sbjct: 438  QGQFDYTKQENTELIKKIQYVNQQKQQSIDSLNDQWQIHNEKLSEQLAINEDKYAKLSIN 497

Query: 605  MENLA------ETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSE 658
               L+      ET+LK        K + + E   LQ + ++    + +++Q       + 
Sbjct: 498  YNQLSKQKQDLETQLKLKEKELESKLEELTEFEQLQLRVNKQNQTIQNLAQQNQQYEATL 557

Query: 659  IKSV----HLEEQIDALSASKKELAL--VIENLKLDKEQLYGTIKDLENDKEDIM----N 708
            +K++      E+QI  L    K+L+   + + L  DK   Y    D  N +   +    N
Sbjct: 558  VKNIDEKKQFEKQIQDLMEKLKDLSQDNLNQQLLSDKIVKYQQEIDKLNKQNSRLLNEKN 617

Query: 709  KLQNYIQENMDLTDKLEKMSAEKISELLAKINH--EEQSKIQTQF---GIDAKIQERDLY 763
            +LQ  I+   D +D L + + EK+ + LA  N   EEQ++  T++    +D   Q  +L 
Sbjct: 618  ELQESIKNEKDKSDLLIQ-NLEKLEDQLALANQEIEEQTQKITKYQKENLDLLKQMDELT 676

Query: 764  IEN---IESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQE 820
             +N   ++ +  +++ +   L + +A+ E+   +L++K       +++ Q    E   ++
Sbjct: 677  AKNKKLLKEQNEEWEEQNNNLLQKLALSENNLLNLQQKNTNQERIIEKLQVFEIENQKKD 736

Query: 821  DELVNRLAVLMDHDRVVE-----KQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQH 875
            D ++N    L D  ++ +     +++++++++  ++ K+ + LL +N  LQ    + +Q 
Sbjct: 737  DYILNLKQQLDDQGQINQFNQNTQEIVDLQNQLLDVNKEKEQLLNDNIQLQNEFGNEKQI 796

Query: 876  Y-NALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLE-IEFN 933
              N + +++ + +  E+E  +Y+T        LK+   + Q + +Q + + E ++ ++  
Sbjct: 797  LENKVDDQSKKLEQYENELQQYKTNQLQFNDKLKQA--QRQLVELQSELQEEQIKSLQLQ 854

Query: 934  TQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMN-LELIDKH 992
            +Q++S   +K  L +  +    + +Q+  + Q     +       E + + + L L+ + 
Sbjct: 855  SQLQSISENKSSLQQNQDLLDIFESQISPRQQATVQQMTETISYTESVQQQDQLHLLKQQ 914

Query: 993  VQKQQ--TQSPDY-TEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESK 1049
            +Q+ Q   Q  D    Q I + N++ + L    E++      I         ++ + +S+
Sbjct: 915  IQQLQEIIQEKDLEINQVIQQKNEMESSLDVAIEKMNNQENLILQLNQENGKLIEEQKSE 974

Query: 1050 LAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQI--KELKETKLTFEMNIP 1107
            +     K+ + E  +Q +  Q+ D +Q  +  +   +EQ+D I  K L++ +      + 
Sbjct: 975  INHQKQKISSQEMVIQSLQSQIEDLQQELQGYENKQKEQEDNIQKKILEQNQEQQLKKLI 1034

Query: 1108 KTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQ-SAKLNT 1166
              +   I S  E ++      D             +  +  +F Q R + +E+ + +L  
Sbjct: 1035 AEKDQEIQSLREQLNKIHEQFDQLQNKSVLSNRSKRSFQVAKFDQFRDINEEENNEELED 1094

Query: 1167 ELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLN-----TEND-NLLSTVAEL 1220
            E    +  +I  E +N +    D++ Q++  Q+KS  EQ N     TE +  LL    EL
Sbjct: 1095 EDDLKFENMILKEQINKK---EDLIKQQE-QQIKSFNEQDNEKSQQTEKEKQLLQNQNEL 1150

Query: 1221 RSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQ 1280
                   + +   ++ E  ++ L Q E    K+    R + S  + +Y+Q  D    ++Q
Sbjct: 1151 LLQEIDKMQKEMEKLKEEQRRMLEQFELQMNKSVISNRSKRSQNQIQYDQFQDLPDDNSQ 1210

Query: 1281 --------EETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSE 1326
                    EE N  V  ++ +  Q ++Q+ +E ++ L+E+   +  +I +L+++
Sbjct: 1211 GSQDEDENEELNLFVLQKKTSDQQKQIQNLQETIQKLKEENNSLQEEINVLKNK 1264



 Score =  128 bits (308), Expect = 2e-27
 Identities = 217/1109 (19%), Positives = 493/1109 (44%), Gaps = 127/1109 (11%)

Query: 475  VNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHK 534
            +N+I + Q Q+ ++L    + ++ K +I +LK  ++ + Q    ++   K   K K +++
Sbjct: 238  LNKINRKQ-QIDEDLLSSARQIDSKTIINELKQDKQNLLQKVKNLEIQLKQEQK-KPSYE 295

Query: 535  LKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMI 594
             KL Q Q+  + F++    +++I+   E+    S +  +L +++   ++        + +
Sbjct: 296  QKLNQAQQIEEQFNEFKKKHQQIIYNLEQEKSTSLEKEQLIKKEAQQKI--------KKL 347

Query: 595  ESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQ 654
            ES +   M E+E   +  +++++   +Q  +  Q+    QQ   ++ +KL +  Q+Q D 
Sbjct: 348  ESQLIALMDELEGRDQI-IESLNQTINQNKNQSQK----QQDVQQLINKLKENEQIQQD- 401

Query: 655  VCSEIKSVHLEEQ--IDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQN 712
            +  +I+ +       ++ L  SK E    ++ ++ D   L G     + +  +++ K+Q 
Sbjct: 402  LNQQIQLMKKNNNTILNELENSKVE----VQKIRKDYSTLQGQFDYTKQENTELIKKIQY 457

Query: 713  YIQENMDLTDKLE---KMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIES 769
              Q+     D L    ++  EK+SE LA IN ++ +K+   +   +K Q++DL     E+
Sbjct: 458  VNQQKQQSIDSLNDQWQIHNEKLSEQLA-INEDKYAKLSINYNQLSK-QKQDL-----ET 510

Query: 770  ELS-KYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLA 828
            +L  K K    +LEE +   E  +  + ++   + +  Q+ Q+        E  LV  + 
Sbjct: 511  QLKLKEKELESKLEE-LTEFEQLQLRVNKQNQTIQNLAQQNQQ-------YEATLVKNI- 561

Query: 829  VLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDL 888
               D  +  EKQ+       ++L +K + L ++N N Q+ LSD    Y   ++K N+   
Sbjct: 562  ---DEKKQFEKQI-------QDLMEKLKDLSQDNLNQQL-LSDKIVKYQQEIDKLNK--- 607

Query: 889  AESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNE 948
               ++++   +  +L+ ++K    +   L++Q  +++ED     N +IE   + +K+   
Sbjct: 608  ---QNSRLLNEKNELQESIKN-EKDKSDLLIQNLEKLEDQLALANQEIEE--QTQKIT-- 659

Query: 949  KYEK-NIEYVTQLEAQLQEYKNNIENLNMNVEELNK---MNLELIDKHVQKQQTQSPDYT 1004
            KY+K N++ + Q++    + K  ++  N   EE N      L L + ++   Q ++ +  
Sbjct: 660  KYQKENLDLLKQMDELTAKNKKLLKEQNEEWEEQNNNLLQKLALSENNLLNLQQKNTNQ- 718

Query: 1005 EQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEM 1064
            E+ I ++       ++KD+ I+ L Q++++     ++  +    ++     +L ++ +E 
Sbjct: 719  ERIIEKLQVFEIENQKKDDYILNLKQQLDDQ--GQINQFNQNTQEIVDLQNQLLDVNKEK 776

Query: 1065 QRVSKQLLD-SKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSD 1123
            +++    +    +   E QIL  + DDQ K+L++ +   E+   KT  +  +  ++    
Sbjct: 777  EQLLNDNIQLQNEFGNEKQILENKVDDQSKKLEQYEN--ELQQYKTNQLQFNDKLKQAQR 834

Query: 1124 DANNVDXXXXXXXXXXXXLKVQEEEEFIQE-RSVLQEQSAKLN---TELQECYTKIIQLE 1179
                V+            L++Q + + I E +S LQ+    L+   +++       +Q  
Sbjct: 835  QL--VELQSELQEEQIKSLQLQSQLQSISENKSSLQQNQDLLDIFESQISPRQQATVQQM 892

Query: 1180 TLNTELTGHDVVNQEQINQLKSKLEQLNT---ENDNLLSTVAELRSSISSAVDQRGFEIA 1236
            T     T   V  Q+Q++ LK +++QL     E D  ++ V + ++ + S++D     +A
Sbjct: 893  TETISYT-ESVQQQDQLHLLKQQIQQLQEIIQEKDLEINQVIQQKNEMESSLD-----VA 946

Query: 1237 ELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVT-SL 1295
                        +    +  L +QL+    K   L++  +S    +  KI + E V  SL
Sbjct: 947  -----------IEKMNNQENLILQLNQENGK---LIEEQKSEINHQKQKISSQEMVIQSL 992

Query: 1296 QNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTE 1355
            Q++++D ++ L+  + K  +  + I+    E ++++                    L   
Sbjct: 993  QSQIEDLQQELQGYENKQKEQEDNIQKKILE-QNQEQQLKKLIAEKDQEIQSLREQLNKI 1051

Query: 1356 NQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSE 1415
            ++ + Q+Q +S+L+         +S              +N+ E    EL  + +LK   
Sbjct: 1052 HEQFDQLQNKSVLS--------NRSKRSFQVAKFDQFRDINEEENNE-ELEDEDDLKFEN 1102

Query: 1416 IYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYET 1475
            +  K       + ++ D  +   QQ+  + ++  + + + E E  +L+ +        + 
Sbjct: 1103 MILKEQ-----INKKEDLIKQQEQQIKSFNEQDNEKSQQTEKEKQLLQNQNELLLQEIDK 1157

Query: 1476 MQKESEI---ERVKLIEELNVKITESVSLNKQVAELNKALEEEVA-----KTNEMQTALE 1527
            MQKE E    E+ +++E+  +++ +SV  N+     N+   ++        +   Q   E
Sbjct: 1158 MQKEMEKLKEEQRRMLEQFELQMNKSVISNRSKRSQNQIQYDQFQDLPDDNSQGSQDEDE 1217

Query: 1528 NQEIEIVTLNDEITNLQNMVRASSSKIQK 1556
            N+E+ +  L  + ++ Q  ++     IQK
Sbjct: 1218 NEELNLFVLQKKTSDQQKQIQNLQETIQK 1246



 Score =  118 bits (283), Expect = 2e-24
 Identities = 231/1119 (20%), Positives = 506/1119 (45%), Gaps = 143/1119 (12%)

Query: 91   SESLANTLKQ-KEILMEKIK----QYKELSKRSS--TTIVRXXXXXXXXXXXXXXXQ--L 141
            S+++ N LKQ K+ L++K+K    Q K+  K+ S    + +               Q  +
Sbjct: 260  SKTIINELKQDKQNLLQKVKNLEIQLKQEQKKPSYEQKLNQAQQIEEQFNEFKKKHQQII 319

Query: 142  GDVTHLSNTIKEKDNALSV-LQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXX 200
             ++    +T  EK+  +    Q K+K +E+ ++ L +++  +DQIIE+ N+  T      
Sbjct: 320  YNLEQEKSTSLEKEQLIKKEAQQKIKKLESQLIALMDELEGRDQIIESLNQ--TINQNKN 377

Query: 201  XXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLL 260
                        +  ++  ++Q++        K     +L ++E+  V +  + +    L
Sbjct: 378  QSQKQQDVQQLINKLKENEQIQQDLNQQIQLMKKNNNTILNELENSKVEVQKIRKDYSTL 437

Query: 261  EAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIAN 320
            +        E+++L ++++                 +   E   E+    E+K +    N
Sbjct: 438  QGQFDYTKQENTELIKKIQYVNQQKQQSIDSLNDQWQIHNEKLSEQLAINEDKYAKLSIN 497

Query: 321  MTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTAS 380
              +L+K+ + LE    Q++   KELE+KL  + TE + +     K +  I   + +N   
Sbjct: 498  YNQLSKQKQDLE---TQLKLKEKELESKLEEL-TEFEQLQLRVNKQNQTIQNLAQQN--- 550

Query: 381  KMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXX 440
                   Q    TL ++ D+K       + E  IQ    DL++K   +S+ +        
Sbjct: 551  -------QQYEATLVKNIDEK------KQFEKQIQ----DLMEKLKDLSQDNL------- 586

Query: 441  XXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKD 500
                   L++   +++QQ ++  +      N+  +NE  ++QE +K E     KD +   
Sbjct: 587  ----NQQLLSDKIVKYQQEIDKLN----KQNSRLLNEKNELQESIKNE-----KDKS-DL 632

Query: 501  LIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQK-TIDNFSKVSDSNKEIVR 559
            LI+ L+  E+Q+   N EI+   + + K +  +   LKQM + T  N   + + N+E   
Sbjct: 633  LIQNLEKLEDQLALANQEIEEQTQKITKYQKENLDLLKQMDELTAKNKKLLKEQNEE--- 689

Query: 560  LTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLL 619
              E+ ++L QK+A  E    NLQ    + +  R+IE     ++ E+EN  + +   I  L
Sbjct: 690  WEEQNNNLLQKLALSENNLLNLQQKNTNQE--RIIEK---LQVFEIEN--QKKDDYILNL 742

Query: 620  ESQKFD--LVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKE 677
            + Q  D   + + +   Q+  +++++L D+++ + +Q+ ++  ++ L+ +      ++K+
Sbjct: 743  KQQLDDQGQINQFNQNTQEIVDLQNQLLDVNK-EKEQLLND--NIQLQNEF----GNEKQ 795

Query: 678  LALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLA 737
               ++EN K+D +      K LE  + +    LQ Y    +   DKL K +  ++ EL +
Sbjct: 796  ---ILEN-KVDDQS-----KKLEQYENE----LQQYKTNQLQFNDKL-KQAQRQLVELQS 841

Query: 738  KINHEE------QSKIQTQFGIDAKIQERDLYIENIESELS-KYKSRICRLEESIAVME- 789
            ++  E+      QS++Q+     + +Q+    ++  ES++S + ++ + ++ E+I+  E 
Sbjct: 842  ELQEEQIKSLQLQSQLQSISENKSSLQQNQDLLDIFESQISPRQQATVQQMTETISYTES 901

Query: 790  ----DRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIE 845
                D+ + L+++  QL   +QEK    ++   Q++E+ + L V ++     E  +L++ 
Sbjct: 902  VQQQDQLHLLKQQIQQLQEIIQEKDLEINQVIQQKNEMESSLDVAIEKMNNQENLILQLN 961

Query: 846  HENKEL--QKKNQILLEENQNLQISLSDMQ-QHYNALVEKANRTDLAESESTKYQTQLRD 902
             EN +L  ++K++I    +Q  +IS  +M  Q   + +E     DL + E   Y+ + ++
Sbjct: 962  QENGKLIEEQKSEI---NHQKQKISSQEMVIQSLQSQIE-----DL-QQELQGYENKQKE 1012

Query: 903  LESNL-KRITHEHQ-----TLIVQKKKEIEDLEIEFNTQIE--SAIRDKKVLNEKYEKNI 954
             E N+ K+I  ++Q      LI +K +EI+ L  + N   E    +++K VL+ + +++ 
Sbjct: 1013 QEDNIQKKILEQNQEQQLKKLIAEKDQEIQSLREQLNKIHEQFDQLQNKSVLSNRSKRSF 1072

Query: 955  EYVTQLEAQLQEYKN-NIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINK 1013
            +      A+  ++++ N E  N  +E+ + +  E  +  +++Q  +  D  +Q   +I  
Sbjct: 1073 QV-----AKFDQFRDINEEENNEELEDEDDLKFE--NMILKEQINKKEDLIKQQEQQIKS 1125

Query: 1014 LNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQ-RVSKQLL 1072
             N    +K ++     Q + N     +  +   + ++ +   +   M E+ + +++K ++
Sbjct: 1126 FNEQDNEKSQQTEKEKQLLQNQNELLLQEIDKMQKEMEKLKEEQRRMLEQFELQMNKSVI 1185

Query: 1073 DSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXX 1132
             ++    + QI    Q DQ ++L +       +  + E + +    +  SD    +    
Sbjct: 1186 SNRSKRSQNQI----QYDQFQDLPDDNSQGSQDEDENEELNLFVLQKKTSDQQKQIQNLQ 1241

Query: 1133 XXXXXXXXXLKVQEEEEFIQER-SVLQEQSAKLNTELQE 1170
                      K++EE   +QE  +VL+ +S  L   ++E
Sbjct: 1242 ETIQ------KLKEENNSLQEEINVLKNKSVPLKPNVEE 1274



 Score =  107 bits (258), Expect = 2e-21
 Identities = 178/933 (19%), Positives = 409/933 (43%), Gaps = 88/933 (9%)

Query: 647  ISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENL--KLDKEQLYGTIKDLENDKE 704
            I+ LQ+ Q   +I+++ L   I +LS    +   +I+ L  ++D  Q   T +D  + +E
Sbjct: 139  IAGLQNVQDQMKIENISLSNTIKSLSQQLSDARYIIQRLYSQVDLNQQQDT-QDNNSTQE 197

Query: 705  D--IMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKI--QER 760
            +  +  + QN+I   ++  ++    S E   E + KI  ++ +KI  +  ID  +    R
Sbjct: 198  NNLVFYEYQNFILRQLNELEQQTLQSLELKEEKMLKIM-KKLNKINRKQQIDEDLLSSAR 256

Query: 761  DLYIENIESELSKYKSRICRLEESIAVM---EDRRYSLERKADQLGSYLQEKQKAYSEYT 817
             +  + I +EL + K  + +  +++ +    E ++ S E+K +Q     Q+ ++ ++E+ 
Sbjct: 257  QIDSKTIINELKQDKQNLLQKVKNLEIQLKQEQKKPSYEQKLNQA----QQIEEQFNEFK 312

Query: 818  IQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYN 877
             +  +++  L    +    +EK+ L      KE Q+K    +++ ++  I+L D  +  +
Sbjct: 313  KKHQQIIYNLE--QEKSTSLEKEQLI----KKEAQQK----IKKLESQLIALMDELEGRD 362

Query: 878  ALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIE 937
             ++E  N+T       ++ Q  ++ L + LK    E++ +     ++I+ ++   NT I 
Sbjct: 363  QIIESLNQTINQNKNQSQKQQDVQQLINKLK----ENEQIQQDLNQQIQLMKKNNNT-IL 417

Query: 938  SAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQ 997
            + + + KV  +K  K  +Y T L+ Q    K     L   ++ +N+   + ID    + Q
Sbjct: 418  NELENSKVEVQKIRK--DYST-LQGQFDYTKQENTELIKKIQYVNQQKQQSIDSLNDQWQ 474

Query: 998  TQSPDYTEQY-INEIN--KL----NALLKQKD--EEIIALNQKINNAQVSYMSMVSDYES 1048
              +   +EQ  INE    KL    N L KQK   E  + L +K   +++  ++     + 
Sbjct: 475  IHNEKLSEQLAINEDKYAKLSINYNQLSKQKQDLETQLKLKEKELESKLEELTEFEQLQL 534

Query: 1049 KLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPK 1108
            ++ +    ++N+ ++ Q+    L+ +    ++ +  +++  +++K+L +  L  ++   K
Sbjct: 535  RVNKQNQTIQNLAQQNQQYEATLVKNIDEKKQFEKQIQDLMEKLKDLSQDNLNQQLLSDK 594

Query: 1109 TEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTEL 1168
               +     I+ ++   + +              K  + +  IQ    L++Q A  N E+
Sbjct: 595  I--VKYQQEIDKLNKQNSRLLNEKNELQESIKNEK-DKSDLLIQNLEKLEDQLALANQEI 651

Query: 1169 QECYTKIIQLETLNTELTGH-DVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSI--- 1224
            +E   KI + +  N +L    D +  +    LK + E+   +N+NLL  +A   +++   
Sbjct: 652  EEQTQKITKYQKENLDLLKQMDELTAKNKKLLKEQNEEWEEQNNNLLQKLALSENNLLNL 711

Query: 1225 --SSAVDQRGFEIAELWKQHLAQREADFQKTEHEL--RVQLSAFESKYEQLLDSVQSSTQ 1280
               +   +R  E  ++++    +++      + +L  + Q++ F    ++++D       
Sbjct: 712  QQKNTNQERIIEKLQVFEIENQKKDDYILNLKQQLDDQGQINQFNQNTQEIVDLQNQLLD 771

Query: 1281 EETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXX 1340
                K   +     LQN+  ++++ L N  +  +  + Q E    + +  ++ F      
Sbjct: 772  VNKEKEQLLNDNIQLQNEFGNEKQILENKVDDQSKKLEQYENELQQYKTNQLQFNDKLKQ 831

Query: 1341 XXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEA 1400
                      +L+ E     Q+Q Q + +I+E  + L+++             R    +A
Sbjct: 832  AQRQLVELQSELQEEQIKSLQLQSQ-LQSISENKSSLQQNQDLLDIFESQISPR---QQA 887

Query: 1401 KVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELA 1460
             V ++T  +   +S              Q+ D+   ++QQ+    ++++++  EK+ E+ 
Sbjct: 888  TVQQMTETISYTES-------------VQQQDQLHLLKQQI----QQLQEIIQEKDLEI- 929

Query: 1461 ILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTN 1520
                      N     + E E      IE++N +    + LN+   E  K +EE+ ++ N
Sbjct: 930  ----------NQVIQQKNEMESSLDVAIEKMNNQENLILQLNQ---ENGKLIEEQKSEIN 976

Query: 1521 EMQTALENQEIEIVTLNDEITNLQNMVRASSSK 1553
              +  + +QE+ I +L  +I +LQ  ++   +K
Sbjct: 977  HQKQKISSQEMVIQSLQSQIEDLQQELQGYENK 1009



 Score = 98.7 bits (235), Expect = 1e-18
 Identities = 182/952 (19%), Positives = 392/952 (41%), Gaps = 66/952 (6%)

Query: 610  ETRLKAISLLESQKFDLVQEL----HILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLE 665
            + +++ ISL  + K  L Q+L    +I+Q+ Y +V+  L      Q +    E   V  E
Sbjct: 148  QMKIENISLSNTIK-SLSQQLSDARYIIQRLYSQVD--LNQQQDTQDNNSTQENNLVFYE 204

Query: 666  EQIDALSASKKELALVIENLKLDKEQLYGTIKDLE--NDKEDIMNKLQNYIQENMDLTDK 723
             Q   L    +     +++L+L +E++   +K L   N K+ I   L +  ++ +D    
Sbjct: 205  YQNFILRQLNELEQQTLQSLELKEEKMLKIMKKLNKINRKQQIDEDLLSSARQ-IDSKTI 263

Query: 724  LEKMSAEKISELLAKI-NHEEQSKI-QTQFGIDAKIQERDLYIENIESELSKYKSRICRL 781
            + ++  +K   LL K+ N E Q K  Q +   + K+ +     E       K++  I  L
Sbjct: 264  INELKQDK-QNLLQKVKNLEIQLKQEQKKPSYEQKLNQAQQIEEQFNEFKKKHQQIIYNL 322

Query: 782  EESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQL 841
            E+  +   ++   ++++A Q    L+ +  A  +     D+++  L   ++ ++   ++ 
Sbjct: 323  EQEKSTSLEKEQLIKKEAQQKIKKLESQLIALMDELEGRDQIIESLNQTINQNKNQSQKQ 382

Query: 842  LEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLR 901
             +++    +L++  QI  + NQ +Q+   +     N L            + +  Q Q  
Sbjct: 383  QDVQQLINKLKENEQIQQDLNQQIQLMKKNNNTILNELENSKVEVQKIRKDYSTLQGQFD 442

Query: 902  DLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEK-NIEYVTQL 960
              +     +  + Q +  QK++ I+ L  ++    E       +  +KY K +I Y  QL
Sbjct: 443  YTKQENTELIKKIQYVNQQKQQSIDSLNDQWQIHNEKLSEQLAINEDKYAKLSINY-NQL 501

Query: 961  EAQLQEYKNNI----ENLNMNVEELNKMNLELIDKHVQKQQTQS-PDYTEQYINEINKLN 1015
              Q Q+ +  +    + L   +EEL +     +  + Q Q  Q+     +QY   + K  
Sbjct: 502  SKQKQDLETQLKLKEKELESKLEELTEFEQLQLRVNKQNQTIQNLAQQNQQYEATLVKNI 561

Query: 1016 ALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSK 1075
               KQ +++I  L +K+ +        +S         + K+   ++E+ +++KQ     
Sbjct: 562  DEKKQFEKQIQDLMEKLKD--------LSQDNLNQQLLSDKIVKYQQEIDKLNKQNSRLL 613

Query: 1076 QHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXX 1135
                ELQ  ++ + D+   L +     E  +      I   T +       N+D      
Sbjct: 614  NEKNELQESIKNEKDKSDLLIQNLEKLEDQLALANQEIEEQTQKITKYQKENLDLLKQMD 673

Query: 1136 XXXXXXLKV--QEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQ 1193
                   K+  ++ EE+ ++ + L ++ A     L     K    E +  +L   ++ NQ
Sbjct: 674  ELTAKNKKLLKEQNEEWEEQNNNLLQKLALSENNLLNLQQKNTNQERIIEKLQVFEIENQ 733

Query: 1194 EQ---INQLKSKLE---QLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQRE 1247
            ++   I  LK +L+   Q+N  N N    + +L++ +     ++     +L   ++ Q +
Sbjct: 734  KKDDYILNLKQQLDDQGQINQFNQN-TQEIVDLQNQLLDVNKEK----EQLLNDNI-QLQ 787

Query: 1248 ADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLR 1307
             +F   +  L  ++     K EQ  + +Q   Q +TN++   +++   Q +L + +  L+
Sbjct: 788  NEFGNEKQILENKVDDQSKKLEQYENELQ---QYKTNQLQFNDKLKQAQRQLVELQSELQ 844

Query: 1308 NLQEKYADVINQIEIL---RSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSY-KQMQ 1363
              Q K   + +Q++ +   +S ++  +                    + TE  SY + +Q
Sbjct: 845  EEQIKSLQLQSQLQSISENKSSLQQNQDLLDIFESQISPRQQATVQQM-TETISYTESVQ 903

Query: 1364 EQSILN-INEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHE 1422
            +Q  L+ + ++  QL++              + N+ E+ +     ++  +++ I Q   E
Sbjct: 904  QQDQLHLLKQQIQQLQEIIQEKDLEINQVIQQKNEMESSLDVAIEKMNNQENLILQLNQE 963

Query: 1423 YTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEI 1482
                + ++  E  + +Q++   E  I+ L  + E         + +    YE  QKE E 
Sbjct: 964  NGKLIEEQKSEINHQKQKISSQEMVIQSLQSQIED--------LQQELQGYENKQKEQED 1015

Query: 1483 ERVKLIEELNVKITESVSLNKQVAELN---KALEEEVAKTNEMQTALENQEI 1531
               K I E N    +   L K +AE +   ++L E++ K +E    L+N+ +
Sbjct: 1016 NIQKKILEQN----QEQQLKKLIAEKDQEIQSLREQLNKIHEQFDQLQNKSV 1063



 Score = 72.1 bits (169), Expect = 1e-10
 Identities = 124/662 (18%), Positives = 281/662 (42%), Gaps = 56/662 (8%)

Query: 951  EKNIEYVTQLEAQLQEYKNNIENLNM--NVEELNKMNLELIDKHVQKQQTQSPDYTEQYI 1008
            +K  +Y  Q + Q     N +  L    N E+  K + +LI+   Q  +  SP       
Sbjct: 47   KKTQDYQFQFKNQTNNQDNYLTFLKSGKNGEQFQKTH-QLINP--QNLRYLSPSNINTAK 103

Query: 1009 NEINKLNALLKQKD---EEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQ 1065
            N+  + N   +Q+D   +EI  L  + +  ++ Y + ++  ++   Q   +  ++   ++
Sbjct: 104  NDCEQNN--FQQQDNSFQEIADLKIRNDKTRMFYQTQIAGLQNVQDQMKIENISLSNTIK 161

Query: 1066 RVSKQLLDSKQHNEELQILVREQD-DQIKELKETKLTFEMNIP--KTEGMIISSTIEPMS 1122
             +S+QL D++     +Q L  + D +Q ++ ++   T E N+   + +  I+    E   
Sbjct: 162  SLSQQLSDARYI---IQRLYSQVDLNQQQDTQDNNSTQENNLVFYEYQNFILRQLNELEQ 218

Query: 1123 DDANNVDXXXXXXXXXXXXL-KVQEEEEFIQE--RSVLQEQSAKLNTELQECYTKIIQ-L 1178
                +++            L K+  +++  ++   S  Q  S  +  EL++    ++Q +
Sbjct: 219  QTLQSLELKEEKMLKIMKKLNKINRKQQIDEDLLSSARQIDSKTIINELKQDKQNLLQKV 278

Query: 1179 ETLNTELTGHDVVN--QEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIA 1236
            + L  +L         ++++NQ +   EQ N         +  L    S+++++      
Sbjct: 279  KNLEIQLKQEQKKPSYEQKLNQAQQIEEQFNEFKKKHQQIIYNLEQEKSTSLEKE----- 333

Query: 1237 ELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQ 1296
            +L K+   Q+    +K E +L   +   E + +Q+++S+  +  +  N+    + V  L 
Sbjct: 334  QLIKKEAQQK---IKKLESQLIALMDELEGR-DQIIESLNQTINQNKNQSQKQQDVQQLI 389

Query: 1297 NKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXX------XXXXXX 1350
            NKL++ E+  ++L ++   +      + +E+E+ KV                        
Sbjct: 390  NKLKENEQIQQDLNQQIQLMKKNNNTILNELENSKVEVQKIRKDYSTLQGQFDYTKQENT 449

Query: 1351 DLRTENQSYKQMQEQSILNINEE----NAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELT 1406
            +L  + Q   Q ++QSI ++N++    N +L +                N    +  +L 
Sbjct: 450  ELIKKIQYVNQQKQQSIDSLNDQWQIHNEKLSEQLAINEDKYAKLSINYNQLSKQKQDLE 509

Query: 1407 HQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKM 1466
             QL+LK+ E+  K  E T        EFE ++ ++ +  + I++L  + +   A L   +
Sbjct: 510  TQLKLKEKELESKLEELT--------EFEQLQLRVNKQNQTIQNLAQQNQQYEATLVKNI 561

Query: 1467 HENANHYETMQKESEIERVKLIEELNVKITES--VSLNKQVAELNKALEEEVAKTNEMQT 1524
             E     + +Q   E  +    + LN ++     V   +++ +LNK     + + NE+Q 
Sbjct: 562  DEKKQFEKQIQDLMEKLKDLSQDNLNQQLLSDKIVKYQQEIDKLNKQNSRLLNEKNELQE 621

Query: 1525 ALENQEIEIVTLNDEITNLQNMVRASSSKIQKHV-SFASDTKQGRD--EQLD--NTMNKE 1579
            +++N++ +   L   +  L++ +  ++ +I++         K+  D  +Q+D     NK+
Sbjct: 622  SIKNEKDKSDLLIQNLEKLEDQLALANQEIEEQTQKITKYQKENLDLLKQMDELTAKNKK 681

Query: 1580 LL 1581
            LL
Sbjct: 682  LL 683


>UniRef50_Q22RB5 Cluster: Putative uncharacterized protein; n=1;
            Tetrahymena thermophila SB210|Rep: Putative
            uncharacterized protein - Tetrahymena thermophila SB210
          Length = 1852

 Score =  147 bits (356), Expect = 3e-33
 Identities = 246/1229 (20%), Positives = 525/1229 (42%), Gaps = 96/1229 (7%)

Query: 400  KKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLE---- 455
            KKI K+  ++L+ + Q +NK       V  +  +           K+  ++QL+      
Sbjct: 355  KKIKKDYESQLKDISQKINKR--SGSIVRLDSISEIEKLREQLEHKEKELSQLKSNTFEL 412

Query: 456  HQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQL 515
              +  +   LI    + E   EIA+ Q ++ QE      + ++  L + L  ++E+   L
Sbjct: 413  SPKSYQAKELIGESADGEYNFEIAENQFKINQEQQQNFLN-DLSKLEQTLLQSQEREEVL 471

Query: 516  NDEIDAANKNMIKVKSNHKLKLKQMQ-KTIDNFSKVSDSNKEIVRLTEELHHLSQKVAEL 574
            N ++   N+N  K  +  K +L+ ++ K+     ++     EI    +E  HL Q+++  
Sbjct: 472  NAKVKQQNENFDKEINELKTQLQSLKSKSEFQEQELQKYQNEIQAKNQEFQHLKQQISMA 531

Query: 575  EEE----KGNLQLHLVDY-----DSGRMIESDVYKKMIEM-ENLAETRLKAISLLESQKF 624
            EE+    K  ++    +Y     D  + IE+  YKK IE+ E+    +  + S  E +  
Sbjct: 532  EEKEKTVKDQMEQDKNNYLNQINDFNQQIEN--YKKQIELNESQIHNQQTSSSQKEEEIN 589

Query: 625  DLVQELHILQQKYD---EVEDK--LADISQLQSDQVCSEIKSVHLEEQIDALSASKKELA 679
             L + +   ++K     E ++K  +  +S ++      E + + + +  ++      E+ 
Sbjct: 590  RLYENMKNEKEKISLALEQKEKGHILILSNMEEQLKIKESQLIDVRKIQESEKIKLTEMV 649

Query: 680  LVIENLK-LDKEQLYGTIKDLENDKEDIMNKLQNY---IQENMDLTDKLEKMSAEKISEL 735
              +E LK +  E+    I+ + N +E I  + +NY   + E     D  E    E+I E+
Sbjct: 650  EKVEELKKILSEKSSKEIELVRNHEEAIQKERENYEVLLTEKQKQWDIKENNFNEQIKEV 709

Query: 736  LAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSL 795
              K++  EQ+K + +  +  +  +    I ++ES+L     ++ + E+ I  ++     L
Sbjct: 710  NEKMSKLEQTKSEEKKNLTNQNSQLQASILSLESKLKSESEKLAQSEQQIKKLQMSSSDL 769

Query: 796  ----ERKADQLGSY----------LQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQL 841
                  K    GS           L+E+ K   E  IQ + L  +   + +        L
Sbjct: 770  INDQNSKITAFGSQVEGLLLEIAALKEQNKKQKELEIQIENLSCQNKKMENELNKKAMNL 829

Query: 842  LEIEHENKELQKKNQILLEENQNLQISLSDMQQHYN---ALVEK-----ANRTDLAESES 893
             ++E + K+L+K+ +IL E+ Q  + S S +Q   N   AL+++       +    E++S
Sbjct: 830  QQVEEQEKDLKKQLKILEEKIQEHESSFSALQLAENEKQALLKQEIASLGEKIKEIETQS 889

Query: 894  TKYQTQLRDLESNLKRITHEHQTL---IVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKY 950
             K + ++ +LE +L  I      L   +V++K E   LE+  + + E   ++K+VL    
Sbjct: 890  DKRKEKIGELEKSLAEIQQVKSALEEQMVKQKSEFSSLELVLSQERE---KNKEVLANMK 946

Query: 951  EKNIEYVTQLEAQLQEYKNNIE-NLNMNVEELNKMNL-ELIDKHVQKQQTQSPDYTEQYI 1008
            +++ +   + E Q+ + K   E  L   +E  +   L E I++  ++ Q Q+ + +E+  
Sbjct: 947  KQSQKEKEEFENQISQQKEQHEIKLRETLEANSGKELQEQIEQIKEQYQKQNKELSEK-C 1005

Query: 1009 NEIN-KLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRV 1067
            NE+N KL +  +++++E+  + +++N    S  SM+  +E  +     + EN   E +++
Sbjct: 1006 NELNLKLESQKQEREKEVTEMKEQLNQKGESIHSMIKKHEEDVINQKKQFEN---EKEKL 1062

Query: 1068 SKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANN 1127
            +KQ  D K    +L+  ++ ++ Q   L+      +  + + E    +   E        
Sbjct: 1063 TKQFNDEKS---QLESQLQGKETQFIALQSQLSLVQQELQEKEKQKKNQEQEHQKI-CRQ 1118

Query: 1128 VDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTG 1187
            ++            +  Q +E+     S+L+E    +   ++  Y +  + ETLN++L+ 
Sbjct: 1119 LENTIAENKAQIESINKQNDEKI---SSLLEENILNVKN-IEARYVQ--EKETLNSQLSE 1172

Query: 1188 HDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQ---HLA 1244
             D   + +INQ++ +L +  +  + L      L    ++ + Q+   + E  +Q      
Sbjct: 1173 QDKQIKVKINQIQEELSKKISSFEELNQQFVSLEEEKNN-LKQQILSLEEEKQQLDLQTK 1231

Query: 1245 QREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEE 1304
            Q++ +F++ E     Q+      +E  +  +Q+   E  +K+V +        + + K E
Sbjct: 1232 QKQQEFEEKELNREKQIEEINKNHEIQMQKMQT---ELDSKVVLINAANVQLVQAKSKIE 1288

Query: 1305 HLRNLQEKY-ADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQ 1363
              +NL   + AD+  QI+I  +E  ++                        ENQS    +
Sbjct: 1289 EYKNLYSSHKADLEKQIQI--NEEREQSFLNKEKEWKEKLDQKNLTLSAFYENQSQISQK 1346

Query: 1364 EQSILN--INEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTH 1421
             + I    I +   Q+ +              + + A+   +E   Q E+K  E   K  
Sbjct: 1347 NEEIQQQRIKQYEQQMTQVQSRFENDIQQLQAK-HSADISSIEQKFQQEIKQMESKLKQQ 1405

Query: 1422 E--YTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKE 1479
            E  +   L Q+ D+ E    Q ++    ++    +KE ++     ++++     ++M  E
Sbjct: 1406 EILHEQLLKQQKDQLEQEHNQEIQ---SLQSEVNQKEDKINQSLTQINQLQAQIDSMNNE 1462

Query: 1480 SEIERVKLI--EELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLN 1537
             +    K+I  E+ + ++ + ++  K   E+    +E V K  + Q    N+EI  + +N
Sbjct: 1463 KKESTNKIIALEKESAQLKQKLTEIKNPEEIQHQKDEGVLKQQQQQIQKLNEEI--ILIN 1520

Query: 1538 DEITNLQNMVRASSSKIQKHVSFASDTKQ 1566
            ++    +  +R     +Q  +  A+D  Q
Sbjct: 1521 NQKNQYEQEIRQLKLTLQNSIKSANDLDQ 1549



 Score =  141 bits (342), Expect = 1e-31
 Identities = 251/1237 (20%), Positives = 536/1237 (43%), Gaps = 125/1237 (10%)

Query: 228  MEAEWKDEKQRLL---KDIESKDVRISSL----EEANKLL-EAARFEISL--EHSKLAQE 277
            ME + K ++ +L+   K  ES+ ++++ +    EE  K+L E +  EI L   H +  Q+
Sbjct: 620  MEEQLKIKESQLIDVRKIQESEKIKLTEMVEKVEELKKILSEKSSKEIELVRNHEEAIQK 679

Query: 278  LEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQ 337
              +              + + +     E+  E+ EK S      +E  K    L + N Q
Sbjct: 680  ERENYEVLLTEKQKQWDIKENNFN---EQIKEVNEKMSKLEQTKSEEKKN---LTNQNSQ 733

Query: 338  IRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQD 397
            ++ +   LE+KL +  +E  A S    K   + S     +  SK+ +  SQ+    L   
Sbjct: 734  LQASILSLESKLKSE-SEKLAQSEQQIKKLQMSSSDLINDQNSKITAFGSQVEGLLLEIA 792

Query: 398  TDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQ 457
              K+ NK +  +LE+ I++L+      E  +++K                 +  L+ + Q
Sbjct: 793  ALKEQNKKQ-KELEIQIENLSCQNKKMENELNKKAMNLQQVEEQEKDLKKQLKILEEKIQ 851

Query: 458  QHMEGPSLIHVGTNTEDV---NEIAKVQEQLKQ-ELNDEIKDVNVKDL------IEKLKS 507
            +H    S + +  N +      EIA + E++K+ E   + +   + +L      I+++KS
Sbjct: 852  EHESSFSALQLAENEKQALLKQEIASLGEKIKEIETQSDKRKEKIGELEKSLAEIQQVKS 911

Query: 508  A-EEQITQLNDEIDAANKNMIKVKSNHKLKL----KQMQKTIDNFSKVSDSNKEI--VRL 560
            A EEQ+ +   E  +    + + +  +K  L    KQ QK  + F       KE   ++L
Sbjct: 912  ALEEQMVKQKSEFSSLELVLSQEREKNKEVLANMKKQSQKEKEEFENQISQQKEQHEIKL 971

Query: 561  TEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLE 620
             E L   S K  EL+E+   ++         + +     +  +++E+  + R K ++ ++
Sbjct: 972  RETLEANSGK--ELQEQIEQIKEQY--QKQNKELSEKCNELNLKLESQKQEREKEVTEMK 1027

Query: 621  SQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELAL 680
             Q     + +H + +K++E  D +    Q ++++     +    + Q+++    K+   +
Sbjct: 1028 EQLNQKGESIHSMIKKHEE--DVINQKKQFENEKEKLTKQFNDEKSQLESQLQGKETQFI 1085

Query: 681  VIEN-LKLDKEQLYGTIKDLENDKED---IMNKLQNYIQENMDLTDKLEKMSAEKISELL 736
             +++ L L +++L    K  +N +++   I  +L+N I EN    + + K + EKIS LL
Sbjct: 1086 ALQSQLSLVQQELQEKEKQKKNQEQEHQKICRQLENTIAENKAQIESINKQNDEKISSLL 1145

Query: 737  AK----INHEEQSKIQTQFGIDAKIQERD----LYIENIESELSKYKSRICRLEESIAVM 788
             +    + + E   +Q +  +++++ E+D    + I  I+ ELSK  S    L +    +
Sbjct: 1146 EENILNVKNIEARYVQEKETLNSQLSEQDKQIKVKINQIQEELSKKISSFEELNQQFVSL 1205

Query: 789  EDRR-------YSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQL 841
            E+ +        SLE +  QL    ++KQ+ + E  +  ++ +  +    +H+  ++K  
Sbjct: 1206 EEEKNNLKQQILSLEEEKQQLDLQTKQKQQEFEEKELNREKQIEEIN--KNHEIQMQKMQ 1263

Query: 842  LEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLR 901
             E++ +   +   N  L++    ++    ++   + A +EK  +  + E     +  + +
Sbjct: 1264 TELDSKVVLINAANVQLVQAKSKIE-EYKNLYSSHKADLEK--QIQINEEREQSFLNKEK 1320

Query: 902  DLESNL--KRIT----HEHQTLIVQKKKEIEDLEI----EFNTQIESAIR-DKKVLNEKY 950
            + +  L  K +T    +E+Q+ I QK +EI+   I    +  TQ++S    D + L  K+
Sbjct: 1321 EWKEKLDQKNLTLSAFYENQSQISQKNEEIQQQRIKQYEQQMTQVQSRFENDIQQLQAKH 1380

Query: 951  EKNIEYVTQ-LEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYIN 1009
              +I  + Q  + ++++ ++ ++   +  E+L K   + +++   ++         Q  +
Sbjct: 1381 SADISSIEQKFQQEIKQMESKLKQQEILHEQLLKQQKDQLEQEHNQEIQSLQSEVNQKED 1440

Query: 1010 EINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSK 1069
            +IN+    + Q   +I ++N +   +    +++  +  ++L Q  T+++N EE   +  +
Sbjct: 1441 KINQSLTQINQLQAQIDSMNNEKKESTNKIIALEKE-SAQLKQKLTEIKNPEEIQHQKDE 1499

Query: 1070 QLLDSKQH-----NEELQILVREQDDQIKELKETKLTFEMNIPKTEGM------------ 1112
             +L  +Q      NEE+ ++  +++   +E+++ KLT + +I     +            
Sbjct: 1500 GVLKQQQQQIQKLNEEIILINNQKNQYEQEIRQLKLTLQNSIKSANDLDQEISNYQAFRN 1559

Query: 1113 -IISSTI-EPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQE 1170
               S +I E  S  + NV             L  +E  EFI  R      S ++  +LQ 
Sbjct: 1560 SYSSQSIHEAESSHSLNVSPTHIPKLNMMA-LSNRETNEFISPRGPASANSKQIELQLQ- 1617

Query: 1171 CYTKIIQLETLNTELTG--HDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAV 1228
                +  LE  N EL    H     ++IN    KL + N ++   L T  +L+ S +   
Sbjct: 1618 ----VKSLENKNKELKESLHQFNQVQKINTEMKKLLEENRKSIKELETELQLKKSDN--- 1670

Query: 1229 DQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKI-- 1286
            +Q   EI     Q L +   DF+  E +L        +++EQ+ D +    +   +KI  
Sbjct: 1671 EQMKTEI-----QKLKEALIDFESFEEKLLEMRQIDMNRFEQVRDKIDDLKEVSQSKIEL 1725

Query: 1287 VTMEQVTSL--QNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXX 1344
            V + Q+ +L  + +L D+ E ++    +Y   I ++ I   EI+++              
Sbjct: 1726 VNIIQMFALNFKKELDDRNEKIK----QYLKKIEKVSIQFREIQEQ----HQEMEQLLLS 1777

Query: 1345 XXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSS 1381
                   +  +NQ   Q Q+ ++   N +++   + S
Sbjct: 1778 NKIEISHIVDQNQKNSQYQQNTLYRSNSQSSDFDRRS 1814



 Score =  135 bits (327), Expect = 8e-30
 Identities = 234/1148 (20%), Positives = 481/1148 (41%), Gaps = 87/1148 (7%)

Query: 470  TNTEDVNEIAKVQEQLKQELNDEI--KDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMI 527
            T  + +   ++ QEQ  Q+  +EI  K+   + L +++  AEE+   + D+++    N +
Sbjct: 491  TQLQSLKSKSEFQEQELQKYQNEIQAKNQEFQHLKQQISMAEEKEKTVKDQMEQDKNNYL 550

Query: 528  KVKSNHKLKLKQMQKTID-NFSKV-------SDSNKEIVRLTEELHHLSQKVA-ELEE-E 577
               ++   +++  +K I+ N S++       S   +EI RL E + +  +K++  LE+ E
Sbjct: 551  NQINDFNQQIENYKKQIELNESQIHNQQTSSSQKEEEINRLYENMKNEKEKISLALEQKE 610

Query: 578  KGNL--------QLHLVDYD--SGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLV 627
            KG++        QL + +      R I+     K+ EM    E   K +S   S++ +LV
Sbjct: 611  KGHILILSNMEEQLKIKESQLIDVRKIQESEKIKLTEMVEKVEELKKILSEKSSKEIELV 670

Query: 628  QELHILQQKYDEVEDKLADISQLQSD----QVCSEIKSVHLEEQIDALSASKKELALVIE 683
            +      QK  E  + L    Q Q D        +IK V+  E++  L  +K E     +
Sbjct: 671  RNHEEAIQKERENYEVLLTEKQKQWDIKENNFNEQIKEVN--EKMSKLEQTKSEEK---K 725

Query: 684  NLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEE 743
            NL     QL  +I  LE+  +    KL    Q+   L      +  ++ S++ A  +  E
Sbjct: 726  NLTNQNSQLQASILSLESKLKSESEKLAQSEQQIKKLQMSSSDLINDQNSKITAFGSQVE 785

Query: 744  QS--KIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQ 801
                +I      + K +E ++ IEN+  +  K ++ + +   ++  +E++   L+++   
Sbjct: 786  GLLLEIAALKEQNKKQKELEIQIENLSCQNKKMENELNKKAMNLQQVEEQEKDLKKQLKI 845

Query: 802  LGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEE 861
            L   +QE + ++S   + E+E   + A+L      + +++ EIE ++ + ++K   L + 
Sbjct: 846  LEEKIQEHESSFSALQLAENE---KQALLKQEIASLGEKIKEIETQSDKRKEKIGELEKS 902

Query: 862  NQNLQISLSDMQQHYNALVEKANRTDLAES-ESTKYQTQLRDLESNLKRITHEHQTLIVQ 920
               +Q   S +++       + +  +L  S E  K +  L +++   ++   E +  I Q
Sbjct: 903  LAEIQQVKSALEEQMVKQKSEFSSLELVLSQEREKNKEVLANMKKQSQKEKEEFENQISQ 962

Query: 921  KKK--EI---EDLEIEFNTQIESAIRDKKVLNEKYEKNI-EYVTQLEAQLQEYKNNIENL 974
            +K+  EI   E LE     +++  I   K   +K  K + E   +L  +L+  K   E  
Sbjct: 963  QKEQHEIKLRETLEANSGKELQEQIEQIKEQYQKQNKELSEKCNELNLKLESQKQEREKE 1022

Query: 975  NMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINN 1034
               ++E      E I   ++K +    +  +Q+ NE  KL      +  ++ +  Q    
Sbjct: 1023 VTEMKEQLNQKGESIHSMIKKHEEDVINQKKQFENEKEKLTKQFNDEKSQLESQLQGKET 1082

Query: 1035 AQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNE-ELQILVREQDDQIK 1093
              ++  S +S  + +L +   + +N E+E Q++ +QL ++   N+ +++ + ++ D++I 
Sbjct: 1083 QFIALQSQLSLVQQELQEKEKQKKNQEQEHQKICRQLENTIAENKAQIESINKQNDEKIS 1142

Query: 1094 ELKETKLTFEMNI-------PKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQ- 1145
             L E  +    NI        +T    +S   + +    N +             L  Q 
Sbjct: 1143 SLLEENILNVKNIEARYVQEKETLNSQLSEQDKQIKVKINQIQEELSKKISSFEELNQQF 1202

Query: 1146 ---EEEEFIQERSVLQEQSAKLNTEL------QECYTKIIQLETLNTELT-GHDVVNQEQ 1195
               EEE+   ++ +L  +  K   +L      QE   K +  E    E+   H++  Q+ 
Sbjct: 1203 VSLEEEKNNLKQQILSLEEEKQQLDLQTKQKQQEFEEKELNREKQIEEINKNHEIQMQKM 1262

Query: 1196 INQLKSKLEQLNTENDNLL---STVAELRSSISS--AVDQRGFEIAELWKQHLAQREADF 1250
              +L SK+  +N  N  L+   S + E ++  SS  A  ++  +I E  +Q    +E ++
Sbjct: 1263 QTELDSKVVLINAANVQLVQAKSKIEEYKNLYSSHKADLEKQIQINEEREQSFLNKEKEW 1322

Query: 1251 QKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKI-VTMEQVTS-LQNKLQD-KEEH-- 1305
            ++   +  + LSAF     Q+    +   Q+   +    M QV S  +N +Q  + +H  
Sbjct: 1323 KEKLDQKNLTLSAFYENQSQISQKNEEIQQQRIKQYEQQMTQVQSRFENDIQQLQAKHSA 1382

Query: 1306 -LRNLQEKYADVINQIE--ILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQM 1362
             + ++++K+   I Q+E  + + EI  E++                   L++E    +  
Sbjct: 1383 DISSIEQKFQQEIKQMESKLKQQEILHEQL-LKQQKDQLEQEHNQEIQSLQSEVNQKEDK 1441

Query: 1363 QEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDA---EAKVLELTHQLELKDSEIYQK 1419
              QS+  IN+  AQ+   +               ++   + K+ E+ +  E++  +    
Sbjct: 1442 INQSLTQINQLQAQIDSMNNEKKESTNKIIALEKESAQLKQKLTEIKNPEEIQHQKDEGV 1501

Query: 1420 THEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANH--YETMQ 1477
              +    + + N+E   +  Q  +YE+ I  L    ++ +        E +N+  +    
Sbjct: 1502 LKQQQQQIQKLNEEIILINNQKNQYEQEIRQLKLTLQNSIKSANDLDQEISNYQAFRNSY 1561

Query: 1478 KESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEV-----AKTNEMQTALENQEIE 1532
                I   +    LNV  T    LN  +A  N+   E +     A  N  Q  L+ Q   
Sbjct: 1562 SSQSIHEAESSHSLNVSPTHIPKLN-MMALSNRETNEFISPRGPASANSKQIELQLQVKS 1620

Query: 1533 IVTLNDEI 1540
            +   N E+
Sbjct: 1621 LENKNKEL 1628



 Score =  123 bits (296), Expect = 5e-26
 Identities = 189/908 (20%), Positives = 383/908 (42%), Gaps = 69/908 (7%)

Query: 723  KLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRL- 781
            K++K    ++ ++  KIN    S ++      ++I++    +E+ E ELS+ KS    L 
Sbjct: 356  KIKKDYESQLKDISQKINKRSGSIVRLDS--ISEIEKLREQLEHKEKELSQLKSNTFELS 413

Query: 782  ------EESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRL-------A 828
                  +E I    D  Y+ E   +Q     +++Q   ++ +  E  L+          A
Sbjct: 414  PKSYQAKELIGESADGEYNFEIAENQFKINQEQQQNFLNDLSKLEQTLLQSQEREEVLNA 473

Query: 829  VLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDL 888
             +   +   +K++ E++ + + L+ K++   +E Q  Q  +    Q +  L ++ +  + 
Sbjct: 474  KVKQQNENFDKEINELKTQLQSLKSKSEFQEQELQKYQNEIQAKNQEFQHLKQQISMAE- 532

Query: 889  AESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNE 948
             E E T      +D  + L +I   +Q  I   KK+IE  E + + Q  S+ + ++ +N 
Sbjct: 533  -EKEKTVKDQMEQDKNNYLNQINDFNQQ-IENYKKQIELNESQIHNQQTSSSQKEEEINR 590

Query: 949  KYE--KNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELID-KHVQKQQTQSPDYTE 1005
             YE  KN +    L  + Q+ K +I  L+   E+L     +LID + +Q+ +        
Sbjct: 591  LYENMKNEKEKISLALE-QKEKGHILILSNMEEQLKIKESQLIDVRKIQESEKIKLTEMV 649

Query: 1006 QYINEINKLNALLKQKDEEII-----ALNQKINNAQVSYMSMVSDYESKLAQFTTKLENM 1060
            + + E+ K+ +    K+ E++     A+ ++  N +V        ++ K   F  +++ +
Sbjct: 650  EKVEELKKILSEKSSKEIELVRNHEEAIQKERENYEVLLTEKQKQWDIKENNFNEQIKEV 709

Query: 1061 EEEMQRVSKQLLDSKQH----NEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISS 1116
             E+M ++ +   + K++    N +LQ  +   + ++K   E     E  I K + M  S 
Sbjct: 710  NEKMSKLEQTKSEEKKNLTNQNSQLQASILSLESKLKSESEKLAQSEQQIKKLQ-MSSSD 768

Query: 1117 TIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSV--LQEQSAKLNTELQECYTK 1174
             I   +                   LK Q +++   E  +  L  Q+ K+  EL +    
Sbjct: 769  LINDQNSKITAFGSQVEGLLLEIAALKEQNKKQKELEIQIENLSCQNKKMENELNKKAMN 828

Query: 1175 IIQLETLNTELTGHDVVNQEQINQLKSKLEQLN-TENDNL------LSTVAELRSSISSA 1227
            + Q+E    +L     + +E+I + +S    L   EN+        ++++ E    I + 
Sbjct: 829  LQQVEEQEKDLKKQLKILEEKIQEHESSFSALQLAENEKQALLKQEIASLGEKIKEIETQ 888

Query: 1228 VDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQE--ETNK 1285
             D+R  +I EL K  LA+ +      E ++  Q S F S  E +L   +   +E     K
Sbjct: 889  SDKRKEKIGELEKS-LAEIQQVKSALEEQMVKQKSEF-SSLELVLSQEREKNKEVLANMK 946

Query: 1286 IVTMEQVTSLQNKL-QDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXX 1344
              + ++    +N++ Q KE+H   L+E      N  + L+ +IE  K  +          
Sbjct: 947  KQSQKEKEEFENQISQQKEQHEIKLRETLE--ANSGKELQEQIEQIKEQY----QKQNKE 1000

Query: 1345 XXXXXXDLRTENQSYKQMQEQSILNINEE-NAQLKKSSXXXXXXXXXXXXRVNDAEAKVL 1403
                  +L  + +S KQ +E+ +  + E+ N + +               +    E +  
Sbjct: 1001 LSEKCNELNLKLESQKQEREKEVTEMKEQLNQKGESIHSMIKKHEEDVINQKKQFENEKE 1060

Query: 1404 ELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILR 1463
            +LT Q   + S++  +             +   V+Q+L E EK+ ++   E +     L 
Sbjct: 1061 KLTKQFNDEKSQLESQLQGKETQFIALQSQLSLVQQELQEKEKQKKNQEQEHQKICRQLE 1120

Query: 1464 LKMHENANHYETMQKESEIERVKLIEE--LNVK------ITESVSLNKQVAELNKALEEE 1515
              + EN    E++ K+++ +   L+EE  LNVK      + E  +LN Q++E +K ++  
Sbjct: 1121 NTIAENKAQIESINKQNDEKISSLLEENILNVKNIEARYVQEKETLNSQLSEQDKQIK-- 1178

Query: 1516 VAKTNEMQTALENQEIEIVTLNDEITNLQ----NMVRASSSKIQKHVSFASDTKQGRDEQ 1571
              K N++Q  L  +      LN +  +L+    N+ +   S  ++       TKQ + E 
Sbjct: 1179 -VKINQIQEELSKKISSFEELNQQFVSLEEEKNNLKQQILSLEEEKQQLDLQTKQKQQEF 1237

Query: 1572 LDNTMNKE 1579
             +  +N+E
Sbjct: 1238 EEKELNRE 1245



 Score =  107 bits (257), Expect = 2e-21
 Identities = 212/1152 (18%), Positives = 475/1152 (41%), Gaps = 99/1152 (8%)

Query: 152  KEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXX 211
            K   N  S LQ  +  +E+ +    EK+ + +Q I+    +++                 
Sbjct: 725  KNLTNQNSQLQASILSLESKLKSESEKLAQSEQQIKKLQMSSSDLINDQNSKITAFGSQV 784

Query: 212  EDT-------KQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAAR 264
            E         K+Q  K +E  I +E     + +++  ++  K + +  +EE  K L+   
Sbjct: 785  EGLLLEIAALKEQNKKQKELEIQIE-NLSCQNKKMENELNKKAMNLQQVEEQEKDLKK-- 841

Query: 265  FEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTEL 324
             ++ +   K+ QE E               L KQ I    E+  EIE +       + EL
Sbjct: 842  -QLKILEEKI-QEHESSFSALQLAENEKQALLKQEIASLGEKIKEIETQSDKRKEKIGEL 899

Query: 325  TKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKS 384
             K +        +I+Q    LE ++    +E  ++     +      R+  +   + MK 
Sbjct: 900  EKSL-------AEIQQVKSALEEQMVKQKSEFSSLELVLSQ-----EREKNKEVLANMKK 947

Query: 385  PWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXG 444
               +   E  NQ + +K  ++EI   E +  +  K+L ++   I E+             
Sbjct: 948  QSQKEKEEFENQISQQK-EQHEIKLRETLEANSGKELQEQIEQIKEQYQKQNKELSEKCN 1006

Query: 445  KDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEK 504
            +  L  + Q + ++         +    E ++ + K  E+    +N + +  N K+ + K
Sbjct: 1007 ELNLKLESQKQEREKEVTEMKEQLNQKGESIHSMIKKHEE--DVINQKKQFENEKEKLTK 1064

Query: 505  LKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEEL 564
              + E+  +QL  ++       I ++S   L  +++Q+           +++I R     
Sbjct: 1065 QFNDEK--SQLESQLQGKETQFIALQSQLSLVQQELQEKEKQKKNQEQEHQKICR----- 1117

Query: 565  HHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKF 624
              L   +AE        Q+  ++  +   I S + + ++ ++N+    ++    L SQ  
Sbjct: 1118 -QLENTIAE-----NKAQIESINKQNDEKISSLLEENILNVKNIEARYVQEKETLNSQLS 1171

Query: 625  DLVQELHI-LQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIE 683
            +  +++ + + Q  +E+  K++   +L    V  E +  +L++QI +L   K++L L  +
Sbjct: 1172 EQDKQIKVKINQIQEELSKKISSFEELNQQFVSLEEEKNNLKQQILSLEEEKQQLDLQTK 1231

Query: 684  NLKLDKEQLYGTIKDLENDKE-DIMNKLQNYIQENM--DLTDKLEKMSAEKISELLAKIN 740
              + + E+     K+L  +K+ + +NK      + M  +L  K+  ++A  +  + AK  
Sbjct: 1232 QKQQEFEE-----KELNREKQIEEINKNHEIQMQKMQTELDSKVVLINAANVQLVQAKSK 1286

Query: 741  HEEQSKIQTQFGIDAK--IQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERK 798
             EE   + +    D +  IQ  +   ++  ++  ++K ++ +   +++   + +  + +K
Sbjct: 1287 IEEYKNLYSSHKADLEKQIQINEEREQSFLNKEKEWKEKLDQKNLTLSAFYENQSQISQK 1346

Query: 799  ADQLGSYLQEKQKAYSEYTIQ-EDELVNRLAVLM-DHDRVVEKQLLEIEHENKELQKK-- 854
             +++    Q++ K Y +   Q +    N +  L   H   +     + + E K+++ K  
Sbjct: 1347 NEEIQ---QQRIKQYEQQMTQVQSRFENDIQQLQAKHSADISSIEQKFQQEIKQMESKLK 1403

Query: 855  NQILLEENQNLQISLSDMQQHYNALVEKA-NRTDLAESESTKYQTQLRDLESNLKRITHE 913
             Q +L E Q L+     ++Q +N  ++   +  +  E +  +  TQ+  L++ +  + +E
Sbjct: 1404 QQEILHE-QLLKQQKDQLEQEHNQEIQSLQSEVNQKEDKINQSLTQINQLQAQIDSMNNE 1462

Query: 914  HQ---TLIVQKKKEIEDL-----EIEFNTQIESAIRDKKVLNEKYE---KNIEYVTQLEA 962
             +     I+  +KE   L     EI+   +I+   +D+ VL ++ +   K  E +  +  
Sbjct: 1463 KKESTNKIIALEKESAQLKQKLTEIKNPEEIQHQ-KDEGVLKQQQQQIQKLNEEIILINN 1521

Query: 963  QLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKD 1022
            Q  +Y+  I  L + ++   K   +L D+ +   Q     Y+ Q I+E    ++L     
Sbjct: 1522 QKNQYEQEIRQLKLTLQNSIKSANDL-DQEISNYQAFRNSYSSQSIHEAESSHSLNVSPT 1580

Query: 1023 E----EIIALNQKINNAQVSYMSMVSDYESKLA-QFTTK-LENMEEEMQRVSKQLLDSKQ 1076
                  ++AL+ +  N  +S     S    ++  Q   K LEN  +E++    Q    ++
Sbjct: 1581 HIPKLNMMALSNRETNEFISPRGPASANSKQIELQLQVKSLENKNKELKESLHQFNQVQK 1640

Query: 1077 HNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXX 1136
             N E++ L+ E    IKEL ET    E+ + K++   + + I+ + +   + +       
Sbjct: 1641 INTEMKKLLEENRKSIKEL-ET----ELQLKKSDNEQMKTEIQKLKEALIDFE----SFE 1691

Query: 1137 XXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQI 1196
                 ++  +   F Q R  + +      ++++     IIQ+  LN +    D    E+I
Sbjct: 1692 EKLLEMRQIDMNRFEQVRDKIDDLKEVSQSKIE--LVNIIQMFALNFKKELDD--RNEKI 1747

Query: 1197 NQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQK-TEH 1255
             Q   K+E+++ +       + E    +   +     EI+ +  Q+  Q+ + +Q+ T +
Sbjct: 1748 KQYLKKIEKVSIQ----FREIQEQHQEMEQLLLSNKIEISHIVDQN--QKNSQYQQNTLY 1801

Query: 1256 ELRVQLSAFESK 1267
                Q S F+ +
Sbjct: 1802 RSNSQSSDFDRR 1813



 Score = 60.9 bits (141), Expect = 3e-07
 Identities = 136/707 (19%), Positives = 303/707 (42%), Gaps = 84/707 (11%)

Query: 151  IKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXX 210
            ++EK+   S L  + K ++  I  +QE++++K    E  N+                   
Sbjct: 1160 VQEKETLNSQLSEQDKQIKVKINQIQEELSKKISSFEELNQ-----------QFVSLEEE 1208

Query: 211  XEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDV-RISSLEEANKLLEAARFEISL 269
              + KQQ+  ++E    ++ + K ++Q    + E K++ R   +EE NK       EI +
Sbjct: 1209 KNNLKQQILSLEEEKQQLDLQTKQKQQ----EFEEKELNREKQIEEINK-----NHEIQM 1259

Query: 270  EHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIE 329
            +  K+  EL+               L   +     + K++IEE  +L  ++  +L K+I+
Sbjct: 1260 Q--KMQTELD-----------SKVVLINAANVQLVQAKSKIEEYKNLYSSHKADLEKQIQ 1306

Query: 330  LLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQL 389
            + E          KE + KL     +     S   +    IS+K+      ++K    Q+
Sbjct: 1307 INEEREQSFLNKEKEWKEKL----DQKNLTLSAFYENQSQISQKNEEIQQQRIKQYEQQM 1362

Query: 390  SSETLNQDTD-KKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTL 448
            +      + D +++     A +  + Q   +++   E  + +++            KD  
Sbjct: 1363 TQVQSRFENDIQQLQAKHSADISSIEQKFQQEIKQMESKLKQQEILHEQLLKQQ--KD-- 1418

Query: 449  IAQLQLEHQQHMEG-PSLIHVGTN--TEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKL 505
              QL+ EH Q ++   S ++   +   + + +I ++Q Q+   +N+E K+   K +  + 
Sbjct: 1419 --QLEQEHNQEIQSLQSEVNQKEDKINQSLTQINQLQAQI-DSMNNEKKESTNKIIALEK 1475

Query: 506  KSAE--EQITQLN--DEID-AANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRL 560
            +SA+  +++T++   +EI    ++ ++K +     KL +    I+N  + +   +EI +L
Sbjct: 1476 ESAQLKQKLTEIKNPEEIQHQKDEGVLKQQQQQIQKLNEEIILINN--QKNQYEQEIRQL 1533

Query: 561  TEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKM-IEMENLAETRLKAISLL 619
               L +  +   +L++E  N Q     Y S  + E++    + +   ++ +  + A+S  
Sbjct: 1534 KLTLQNSIKSANDLDQEISNYQAFRNSYSSQSIHEAESSHSLNVSPTHIPKLNMMALSNR 1593

Query: 620  ESQKF--------------DLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLE 665
            E+ +F              +L  ++  L+ K  E+++ L   +Q+Q  ++ +E+K + LE
Sbjct: 1594 ETNEFISPRGPASANSKQIELQLQVKSLENKNKELKESLHQFNQVQ--KINTEMKKL-LE 1650

Query: 666  EQIDALSASKKELALV---IENLKLDKEQLYGTIKDLENDKEDIMNKLQ---NYIQENMD 719
            E   ++   + EL L     E +K + ++L   + D E+ +E ++   Q   N  ++  D
Sbjct: 1651 ENRKSIKELETELQLKKSDNEQMKTEIQKLKEALIDFESFEEKLLEMRQIDMNRFEQVRD 1710

Query: 720  LTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRIC 779
              D L+++S  KI EL   +N  +   +  +  +D + ++   Y++ IE    +++    
Sbjct: 1711 KIDDLKEVSQSKI-EL---VNIIQMFALNFKKELDDRNEKIKQYLKKIEKVSIQFREIQE 1766

Query: 780  RLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNR 826
            + +E   ++   +  +    DQ     Q +Q        Q  +   R
Sbjct: 1767 QHQEMEQLLLSNKIEISHIVDQNQKNSQYQQNTLYRSNSQSSDFDRR 1813


>UniRef50_Q13439 Cluster: Golgin subfamily A member 4; n=34;
            Tetrapoda|Rep: Golgin subfamily A member 4 - Homo sapiens
            (Human)
          Length = 2230

 Score =  147 bits (356), Expect = 3e-33
 Identities = 195/948 (20%), Positives = 409/948 (43%), Gaps = 73/948 (7%)

Query: 680  LVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKM----------SA 729
            LV  +  L+KEQL   ++ +E        K    +     L  + +K+          S 
Sbjct: 127  LVGNSDSLNKEQLIQRLRRMERSLSSYRGKYSELVTAYQMLQREKKKLQGILSQSQDKSL 186

Query: 730  EKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVME 789
             +I+EL  ++  ++Q+K   Q   DA ++E+D YI  +++++S  K R+     ++ V++
Sbjct: 187  RRIAELREELQMDQQAKKHLQEEFDASLEEKDQYISVLQTQVSLLKQRLRNGPMNVDVLK 246

Query: 790  DRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENK 849
                 LE +A+      +E  ++  E  +++   V  L  L    +  E  L   +   +
Sbjct: 247  PLP-QLEPQAEVFTK--EENPESDGEPVVEDGTSVKTLETLQQRVKRQENLLKRCKETIQ 303

Query: 850  ELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKR 909
              +++  +L  E + LQ  L +  Q     +EK    DL  +E TK  TQLRD ++ +++
Sbjct: 304  SHKEQCTLLTSEKEALQEQLDERLQE----LEKIK--DLHMAEKTKLITQLRDAKNLIEQ 357

Query: 910  ITHEHQTLIVQKKKEI-EDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYK 968
            +  +   +I + K+++ E LE++     +   R K++  +  E   +      A  +E +
Sbjct: 358  LEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELE 417

Query: 969  NNIENLNMNVEELNKMNLELID--KHVQKQQTQSPDYTEQYINEI-NKLNALLKQKDEEI 1025
              +       E   K+  E+ +  K ++K   +     +Q ++ +  ++  ++K+  EE 
Sbjct: 418  KALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQ 477

Query: 1026 IALNQKINNAQVS--YMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQI 1083
            IA  QK++  +++     +    +++  +F  +++   E+ Q    ++   K+  E L +
Sbjct: 478  IAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQESLAL 537

Query: 1084 ---------LVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXX 1134
                     ++ E ++++++L++   T+   I + E  +  S  E  +   +        
Sbjct: 538  EELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAE 597

Query: 1135 XXXXXXXLKVQEEEEFIQERSVLQEQSA----KLNTELQECYTKIIQL-----ETLNTEL 1185
                   + V  E+   +  S+  +Q A    KL    Q+  T++ +L     +   T L
Sbjct: 598  KNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKETLL 657

Query: 1186 TGHDVVNQEQINQLKSK-LEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLA 1244
               +++ Q  I ++  K LE+L+ +   L S  +EL S +  A  +   E++ L  Q   
Sbjct: 658  KDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSEL-SEVLKARHKLEEELSVLKDQ--- 713

Query: 1245 QREADFQKTEHELRVQLSAFESKYEQLLDSV--QSSTQEETNKIVTMEQVTSLQNKLQDK 1302
                   K + EL  ++   ++ ++Q +DS+  +     +  +    +Q+  L+  L+++
Sbjct: 714  -----TDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKER 768

Query: 1303 EEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQM 1362
            ++HL+  Q    ++  + +I RSE E ++ +                   +   +   Q+
Sbjct: 769  DKHLKEHQAHVENL--EADIKRSEGELQQAS--AKLDVFQSYQSATHEQTKAYEEQLAQL 824

Query: 1363 QEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQK--- 1419
            Q Q +L++  E   L K               ++  + +V +L  QLE ++SE+ QK   
Sbjct: 825  Q-QKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKS 883

Query: 1420 -THEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQK 1478
             T  Y   L   N E E  +Q LVE E  I  +   ++ E+ IL  K+    +    + +
Sbjct: 884  LTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNE 943

Query: 1479 ESEIERVKLIEELNVKITESVSLNKQVAE-LNKALEEEVAKTNEMQTALENQEIEIVTLN 1537
            E E  + K  E+   K+ +     K++ E L K L ++ AK   ++  LEN  +E+    
Sbjct: 944  EYE-TKFKNQEKKMEKVKQKA---KEMQETLKKKLLDQEAK---LKKELENTALELSQKE 996

Query: 1538 DEI-TNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAV 1584
             +    +  M +A+S+ I   VS     ++ + E L     +EL D +
Sbjct: 997  KQFNAKMLEMAQANSAGISDAVSRLETNQKEQIESLTEVHRRELNDVI 1044



 Score =  139 bits (337), Expect = 5e-31
 Identities = 267/1403 (19%), Positives = 597/1403 (42%), Gaps = 119/1403 (8%)

Query: 215  KQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKL 274
            +++ T +++  I  +A  ++  ++ L+ ++ K   + SL      +  AR ++  E S L
Sbjct: 651  QEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVL 710

Query: 275  AQELEQXXXXXXXXXXXXXXLAKQSIEPSCEE-KTEIE--EKGSLEIANMTELTKKIELL 331
              + ++                +Q ++   +E +  I+  EK   +  N  EL     LL
Sbjct: 711  KDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLEL-----LL 765

Query: 332  EHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKM-KSPWSQLS 390
            +  +  +++    +EN  A +      +   S K     S +S  +  +K  +   +QL 
Sbjct: 766  KERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQ 825

Query: 391  SETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIA 450
             + L+ +T++ +   ++A++E   + +  +L    + I  +D            +  + +
Sbjct: 826  QKLLDLETERILLTKQVAEVEAQKKDVCTEL--DAHKIQVQDLMQQLEKQNSEMEQKVKS 883

Query: 451  QLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEE 510
              Q+   +  +G          E   +I   +E +  ++ +  K   ++ L +KL + E+
Sbjct: 884  LTQVYESKLEDG------NKEQEQTKQILVEKENMILQMREGQKK-EIEILTQKLSAKED 936

Query: 511  QITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQK 570
             I  LN+E +   KN  K     K K K+MQ+T+    K+ D      +L +EL + + +
Sbjct: 937  SIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKK--KLLDQE---AKLKKELENTALE 991

Query: 571  VAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQEL 630
            +++ E++     L +   +S  +  SD   ++   E   + +++  SL E  + +L   +
Sbjct: 992  LSQKEKQFNAKMLEMAQANSAGI--SDAVSRL---ETNQKEQIE--SLTEVHRRELNDVI 1044

Query: 631  HILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKE 690
             I ++K ++  ++L +I ++Q  +   E+    L+++I      K+E+   I  LK +  
Sbjct: 1045 SIWEKKLNQQAEELQEIHEIQLQEKEQEV--AELKQKILLFGCEKEEMNKEITWLKEEGV 1102

Query: 691  QLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQ 750
            +   T+ +L+   +     + +  Q+   L   LEK+  +    L      +EQ      
Sbjct: 1103 KQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKM 1162

Query: 751  FGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQ--- 807
               + K +  +L    +++   +++S     E+S   +ED+    ++ +++L   L    
Sbjct: 1163 LAEEDKRKVSEL-TSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLSEELAIQLDICC 1221

Query: 808  EKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQI 867
            +K +A  E   + +EL+N   +       +  ++   +H   ++  K  +L++       
Sbjct: 1222 KKTEALLE--AKTNELIN---ISSSKTNAILSRISHCQHRTTKV--KEALLIKT-----C 1269

Query: 868  SLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIED 927
            ++S+++     L E+ N  +++  ++T    QL + E+ +K +  + ++L+ +K    E 
Sbjct: 1270 TVSELEAQLRQLTEEQNTLNISFQQATH---QLEEKENQIKSMKADIESLVTEK----EA 1322

Query: 928  LEIEFNTQIESAIRDKKV---LNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKM 984
            L+ E   Q ++A   +     L ++  +NI  VT ++ +L+E K  I +L+  + +LN  
Sbjct: 1323 LQKEGGNQQQAASEKESCITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQ 1382

Query: 985  NLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVS 1044
                I   + +++       +QY  E  +L   ++    ++  L+++    ++S +  V 
Sbjct: 1383 LQNSIS--LSEKEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLSKE----KISALEQVD 1436

Query: 1045 DYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQIL-VREQDDQIKELKETKLTFE 1103
            D+ +K +++  K ++   + Q   K+L    Q   EL+     E+D+QI  LKE      
Sbjct: 1437 DWSNKFSEWKKKAQSRFTQHQNTVKEL----QIQLELKSKEAYEKDEQINLLKEELDQQN 1492

Query: 1104 MNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAK 1163
                  +G +     + M    +N++             ++ E E+ I ++++  E    
Sbjct: 1493 KRFDCLKGEMEDDKSK-MEKKESNLETELKSQTA-----RIMELEDHITQKTIEIES--- 1543

Query: 1164 LNTELQEC-YTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRS 1222
            LN  L+     K I+ + L  +L     + +E+ N++K   E++ T  + + S  AEL +
Sbjct: 1544 LNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELET 1603

Query: 1223 S------ISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQ 1276
                   ++ +V  +  E+  L  +  ++  A   + + +   +++A +   +QLL  ++
Sbjct: 1604 KKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIK---KQLLSQME 1660

Query: 1277 SSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADV-INQIEILRSEIEDEKV-AF 1334
               +EE  K  T   ++ L  KLQ++E  +  L+EK   V  +Q E L      + V A+
Sbjct: 1661 E--KEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVAAY 1718

Query: 1335 XXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSIL-NINEENAQLKKSSXXXXXXXXXXXX 1393
                            + +         +++ +L  + +E  +   S             
Sbjct: 1719 TEQEEADSQGCVQKTYEEKISVLQRNLTEKEKLLQRVGQEKEETVSSHFEMRCQYQERLI 1778

Query: 1394 RVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDE----------------FENV 1437
            ++  AEAK  E    +     E+ +K  +Y++ + Q  ++                F++V
Sbjct: 1779 KLEHAEAKQHEDQSMIGHLQEELEEKNKKYSLIVAQHVEKEGGKNNIQAKQNLENVFDDV 1838

Query: 1438 RQQLVE-------YEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEE 1490
            ++ L E        E++I++L      +  + R++M E  + YE +Q   +++      E
Sbjct: 1839 QKTLQEKELTCQILEQKIKELDSCLVRQKEVHRVEMEELTSKYEKLQALQQMDGRNKPTE 1898

Query: 1491 LNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRAS 1550
            L  + TE  S +  V    K L    A+ N+++  L   E E   L  EI  LQ  +R  
Sbjct: 1899 LLEENTEEKSKSHLVQP--KLLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRML 1956

Query: 1551 SSKIQKHVS-FASDTKQGRDEQL 1572
              + Q+ +     +  Q R+E++
Sbjct: 1957 RKEHQQELEILKKEYDQEREEKI 1979



 Score =  132 bits (319), Expect = 8e-29
 Identities = 217/1121 (19%), Positives = 473/1121 (42%), Gaps = 88/1121 (7%)

Query: 487  QELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDN 546
            ++L      +N + LI++L+  E  ++    +         ++ + +++  ++ +K    
Sbjct: 125  EDLVGNSDSLNKEQLIQRLRRMERSLSSYRGKYS-------ELVTAYQMLQREKKKLQGI 177

Query: 547  FSKVSDSN-KEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEM 605
             S+  D + + I  L EEL    Q    L+EE          Y S    +  + K+ +  
Sbjct: 178  LSQSQDKSLRRIAELREELQMDQQAKKHLQEEFDASLEEKDQYISVLQTQVSLLKQRLRN 237

Query: 606  ENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLE 665
              +    LK +  LE Q     +E +        VED  + +  L++ Q   + +   L+
Sbjct: 238  GPMNVDVLKPLPQLEPQAEVFTKEENPESDGEPVVEDGTS-VKTLETLQQRVKRQENLLK 296

Query: 666  EQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIM---NKLQNYIQENMDLTD 722
               + + + K++  L+    +  +EQL   +++LE  K+  M    KL   +++  +L +
Sbjct: 297  RCKETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIE 356

Query: 723  KLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSK-YKSRICRL 781
            +LE+     I+E   +++   + K +    + ++I++     E +  +  K  ++    L
Sbjct: 357  QLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEEL 416

Query: 782  EESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRL--AVLMDHDRVVEK 839
            E++++  +    +  +   ++   ++  +K   E  I   + ++R+   V+    +  E+
Sbjct: 417  EKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEE 476

Query: 840  QLLEIE--HENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQ 897
            Q+ +++  HE KEL +K Q   E  + LQ    + Q+     +EK+    L  S+  + Q
Sbjct: 477  QIAKLQKLHE-KELARKEQ---ELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQ 532

Query: 898  TQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYV 957
              L      L+ +  + + ++ + + ++ DL+ E  T     +  +  L +  ++N    
Sbjct: 533  ESLA-----LEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQS 587

Query: 958  TQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPD-YTEQYINEINKLNA 1016
              L   L+  KN        + E +K  LE +        T+      +QY  E+ KL  
Sbjct: 588  KDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLRE 647

Query: 1017 LLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQ 1076
              +Q+ E ++   + I  A +  M+       KL    T+LE++  E+  V K      +
Sbjct: 648  KCEQEKETLLKDKEIIFQAHIEEMN--EKTLEKLDVKQTELESLSSELSEVLKA---RHK 702

Query: 1077 HNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXX 1136
              EEL +L ++Q D++K+  E K+  + N  + +   + S I+         +       
Sbjct: 703  LEEELSVL-KDQTDKMKQELEAKMDEQKNHHQQQ---VDSIIKEHEVSIQRTEKALKDQI 758

Query: 1137 XXXXXLKVQEEEEFIQERSV----LQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVN 1192
                 L ++E ++ ++E       L+    +   ELQ+   K+   ++  +         
Sbjct: 759  NQLELL-LKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAY 817

Query: 1193 QEQINQLKSKLEQLNTENDNLLSTVAEL---RSSISSAVDQRGFEIAELWKQHLAQREAD 1249
            +EQ+ QL+ KL  L TE   L   VAE+   +  + + +D    ++ +L +Q        
Sbjct: 818  EEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQ-------- 869

Query: 1250 FQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNL 1309
             +K   E+  ++ +    YE  L+   +  QE+T +I+  ++   LQ +   K+E +  L
Sbjct: 870  LEKQNSEMEQKVKSLTQVYESKLED-GNKEQEQTKQILVEKENMILQMREGQKKE-IEIL 927

Query: 1310 QEKYADVINQIEILRSEIE----DEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQ 1365
             +K +   + I IL  E E    +++                    L  +    K+  E 
Sbjct: 928  TQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELEN 987

Query: 1366 SILNINEE----NAQLKKSSXXXXXXXXXXXXRVNDAEAKVLE-LT--HQLELKD----- 1413
            + L ++++    NA++ + +            R+   + + +E LT  H+ EL D     
Sbjct: 988  TALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQKEQIESLTEVHRRELNDVISIW 1047

Query: 1414 -SEIYQKTHE----YTITLTQRNDEFENVRQQLV----EYEKRIEDLTYEKE------SE 1458
              ++ Q+  E    + I L ++  E   ++Q+++    E E+  +++T+ KE      + 
Sbjct: 1048 EKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTT 1107

Query: 1459 LAILRLKMHENANHYETM-QKESEIER--VKLIEELNVKITESVSLNKQVAELNKALEEE 1515
            L  L+ ++ + + H  ++ Q E++++    KL  +LN  + E+  L +Q+ EL    EE+
Sbjct: 1108 LNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEED 1167

Query: 1516 VAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQK 1556
              K +E+ + L+  + E  +L          +   S + +K
Sbjct: 1168 KRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKK 1208



 Score =  128 bits (310), Expect = 9e-28
 Identities = 258/1473 (17%), Positives = 618/1473 (41%), Gaps = 139/1473 (9%)

Query: 150  TIKEKDNALSVLQVKMKIMETTI------LDLQEKINEKDQIIEAKNKATTXXXXXXXXX 203
            +++EKD  +SVLQ ++ +++  +      +D+ + + + +   E   K            
Sbjct: 213  SLEEKDQYISVLQTQVSLLKQRLRNGPMNVDVLKPLPQLEPQAEVFTKEENPESDGEPVV 272

Query: 204  XXXXXXXXEDTKQQMTKMQENFIAMEAEW-KDEKQRLLKDIESKDVRISSLEEANKLLEA 262
                     +T QQ  K QEN +    E  +  K++       K+     L+E  + LE 
Sbjct: 273  EDGTSVKTLETLQQRVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQELEK 332

Query: 263  ARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMT 322
             +     E +KL  +L                 AK  IE     + E ++KG +      
Sbjct: 333  IKDLHMAEKTKLITQLRD---------------AKNLIE-----QLE-QDKGMVIAETKR 371

Query: 323  ELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKM 382
            ++ + +E+ E    Q+R   K++     T G E +     S++ +     +   +TA K 
Sbjct: 372  QMHETLEMKEEEIAQLRSRIKQM----TTQGEELREQKEKSERAA-FEELEKALSTAQKT 426

Query: 383  KSPWSQLSSETLNQ-DTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXX 441
            +    +L +E   Q  T +K ++ E   L+  +  + +++VD     SE+          
Sbjct: 427  EEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQ--------- 477

Query: 442  XXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDL 501
                   IA+LQ  H++ +                E+ K  +  ++E  +++K    K  
Sbjct: 478  -------IAKLQKLHEKEL-----------ARKEQELTKKLQTREREFQEQMKVALEKSQ 519

Query: 502  IEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNF-SKVSDSNKEIVRL 560
             E LK ++E+  Q +  ++        + +  + KL+ +Q+  + + +++ +    + + 
Sbjct: 520  SEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKS 579

Query: 561  TEELHHLSQKVA---ELEEEKGNLQL------HLVDYDSGRMIESDVYKKMIE-MENLAE 610
             +E  + S+ +A   E E+ K N ++      H  + +S +  +  ++ + ++ ++   +
Sbjct: 580  LQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQ 639

Query: 611  TRLKAI-SLLESQKFDLVQELHILQQKY-DEVEDKLADISQLQSDQVCSEIKSVHLEEQI 668
            T ++ +    E +K  L+++  I+ Q + +E+ +K   + +L   Q   E  S  L E +
Sbjct: 640  TEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKT--LEKLDVKQTELESLSSELSEVL 697

Query: 669  DALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMS 728
             A    ++EL+++ +     K++L   + + +N  +  ++ +    + ++  T+K  K  
Sbjct: 698  KARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQ 757

Query: 729  AEKISELLAKINHEEQSKIQTQF-GIDAKIQERDLYIENIESELSKYKSRICRLEESIAV 787
              ++ ELL K   +   + Q     ++A I+  +  ++   ++L  ++S      E    
Sbjct: 758  INQL-ELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKA 816

Query: 788  MEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHE 847
             E++   L++K   L +      K  +E   Q+ ++   L     H   V+  + ++E +
Sbjct: 817  YEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDA---HKIQVQDLMQQLEKQ 873

Query: 848  NKELQKKNQILLEENQN-LQISLSDMQQHYNALVEKANRT-DLAESESTKYQTQLRDL-- 903
            N E+++K + L +  ++ L+    + +Q    LVEK N    + E +  + +   + L  
Sbjct: 874  NSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSA 933

Query: 904  -ESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNE--KYEKNIEYVTQL 960
             E ++  +  E++T    ++K++E ++ +     E+    KK+L++  K +K +E  T L
Sbjct: 934  KEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETL--KKKLLDQEAKLKKELEN-TAL 990

Query: 961  EAQLQEYKNNIENLNMNVEELNKMNL-ELIDKHVQKQQTQSPDYTEQYINEINKLNALLK 1019
            E   +E + N + L M   + N   + + + +    Q+ Q    TE +  E+N + ++ +
Sbjct: 991  ELSQKEKQFNAKMLEM--AQANSAGISDAVSRLETNQKEQIESLTEVHRRELNDVISIWE 1048

Query: 1020 QKDEEIIALNQKINNAQVSYMSM-VSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHN 1078
            +K  +     Q+I+  Q+      V++ + K+  F  + E M +E+  + ++ +      
Sbjct: 1049 KKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTL 1108

Query: 1079 EELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXX 1138
             ELQ  ++++   +  L + +   + ++ K E  +  S  E        V+         
Sbjct: 1109 NELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDK 1168

Query: 1139 XXXLKVQEEEEFIQER-SVLQEQSAKLNTELQECYTKIIQLETLNTELTGH-DVVNQEQI 1196
                ++  + +   E    L+    K N  L++   K ++ + L+ EL    D+  ++  
Sbjct: 1169 RKVSELTSKLKTTDEEFQSLKSSHEKSNKSLED---KSLEFKKLSEELAIQLDICCKKTE 1225

Query: 1197 NQLKSKLEQL----NTENDNLLSTVAELR---SSISSAVDQRGFEIAELWKQ--HLAQRE 1247
              L++K  +L    +++ + +LS ++  +   + +  A+  +   ++EL  Q   L + +
Sbjct: 1226 ALLEAKTNELINISSSKTNAILSRISHCQHRTTKVKEALLIKTCTVSELEAQLRQLTEEQ 1285

Query: 1248 ADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLR 1307
                 +  +   QL   E++ + +   ++S     T K    ++  + Q    +KE  + 
Sbjct: 1286 NTLNISFQQATHQLEEKENQIKSMKADIESLV---TEKEALQKEGGNQQQAASEKESCIT 1342

Query: 1308 NLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSI 1367
             L+++ ++ IN + +++ E++++KV                  +++ +N      +E +I
Sbjct: 1343 QLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDL------NVQLQNSISLSEKEAAI 1396

Query: 1368 LNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITL 1427
             ++ ++  + K                ++  +   LE       K SE  +K        
Sbjct: 1397 SSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQS---RF 1453

Query: 1428 TQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKL 1487
            TQ  +  + ++ QL    K      YEK+ ++ +L+ ++ +    ++ ++ E E ++ K+
Sbjct: 1454 TQHQNTVKELQIQLELKSKE----AYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKM 1509

Query: 1488 IEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMV 1547
                           K+ + L   L+ + A+  E++  +  + IEI +LN+ + N     
Sbjct: 1510 --------------EKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQK 1555

Query: 1548 RASSSKIQKHVSFASDTKQGRDEQLDNTMNKEL 1580
                 ++ + +    +  + +D ++     K L
Sbjct: 1556 DIEHKELVQKLQHFQELGEEKDNRVKEAEEKIL 1588



 Score =  113 bits (271), Expect = 5e-23
 Identities = 172/874 (19%), Positives = 392/874 (44%), Gaps = 76/874 (8%)

Query: 246  KDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCE 305
            K   +S LE   + L   +  +++   +   +LE+              L  +  E   +
Sbjct: 1267 KTCTVSELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLVTEK-EALQK 1325

Query: 306  EKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKK 365
            E    ++  S + + +T+L K  EL E++N  +    +EL+ K   + + SK ++  + +
Sbjct: 1326 EGGNQQQAASEKESCITQLKK--ELSENINA-VTLMKEELKEKKVEISSLSKQLTDLNVQ 1382

Query: 366  GSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKE 425
                IS        S ++  + +   E L+Q  D     + ++K E +      D    +
Sbjct: 1383 LQNSISLSEKEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLSK-EKISALEQVDDWSNK 1441

Query: 426  YVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQL 485
            +   +K             K+  I QL+L+ ++  E    I++    E++++  K  + L
Sbjct: 1442 FSEWKKKAQSRFTQHQNTVKELQI-QLELKSKEAYEKDEQINL--LKEELDQQNKRFDCL 1498

Query: 486  KQELNDEIKDVNVKD--LIEKLKSA-------EEQITQLNDEIDAANKNMIKVKSNHKLK 536
            K E+ D+   +  K+  L  +LKS        E+ ITQ   EI++ N+ +        ++
Sbjct: 1499 KGEMEDDKSKMEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIE 1558

Query: 537  LKQMQKTIDNFSKVSDSNKEIVRLTEE-LHHLSQKV----AELEEEKGNLQLHLVDYDSG 591
             K++ + + +F ++ +     V+  EE +  L  +V    AELE +K  L+ H+      
Sbjct: 1559 HKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELE-HVNLSVKS 1617

Query: 592  RMIESDVYKKMIEMEN---LAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADIS 648
            +  E    +  +E E+   LAE + KA   + + K  L+ ++   +++Y +  +  + +S
Sbjct: 1618 KEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTE--SHLS 1675

Query: 649  QLQSDQVCSEIKSVH-LEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIM 707
            +L + ++    + VH LEE++ ++ +S+ E  +V  + K             E ++ D  
Sbjct: 1676 ELNT-KLQEREREVHILEEKLKSVESSQSETLIVPRSAK-------NVAAYTEQEEADSQ 1727

Query: 708  NKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENI 767
              +Q   +E + +   L++   EK  +LL ++  E++  + + F +  + QER + +E+ 
Sbjct: 1728 GCVQKTYEEKISV---LQRNLTEK-EKLLQRVGQEKEETVSSHFEMRCQYQERLIKLEHA 1783

Query: 768  ESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRL 827
            E++  + +S I  L+E +   ++++YSL           Q  +K   +  IQ  +  N  
Sbjct: 1784 EAKQHEDQSMIGHLQEELE-EKNKKYSL--------IVAQHVEKEGGKNNIQAKQ--NLE 1832

Query: 828  AVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTD 887
             V  D  + ++++ L  +   +++++ +  L+ + +  ++ + ++   Y  L        
Sbjct: 1833 NVFDDVQKTLQEKELTCQILEQKIKELDSCLVRQKEVHRVEMEELTSKYEKL------QA 1886

Query: 888  LAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLN 947
            L + +     T+L +  +  K  +H  Q  ++    E +  ++EF  ++  A R+K+ L 
Sbjct: 1887 LQQMDGRNKPTELLEENTEEKSKSHLVQPKLL-SNMEAQHNDLEF--KLAGAEREKQKLG 1943

Query: 948  EKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQY 1007
            ++    +     L    +E++  +E L    ++      E  +K  Q+Q+     +    
Sbjct: 1944 KEI---VRLQKDLRMLRKEHQQELEILKKEYDQ------EREEKIKQEQEDLELKHNSTL 1994

Query: 1008 INEINKLNALLKQKDEEI-IALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQR 1066
               + + N  L QK++E+ + + + IN AQ     ++  ++ +  Q   K+   +++++R
Sbjct: 1995 KQLMREFNTQLAQKEQELEMTIKETINKAQEVEAELLESHQEETNQLLKKIAEKDDDLKR 2054

Query: 1067 VSK---QLLDSKQHNEELQILVREQDDQIKELKE 1097
             +K   ++LD+++  EE+   VR+   Q++EL++
Sbjct: 2055 TAKRYEEILDARE--EEMTAKVRDLQTQLEELQK 2086



 Score = 46.0 bits (104), Expect = 0.009
 Identities = 109/596 (18%), Positives = 243/596 (40%), Gaps = 65/596 (10%)

Query: 146  HLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXX 205
            H     +EKDN +   + K+  +E  +  ++ ++  K + +E  N +             
Sbjct: 1568 HFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALED 1627

Query: 206  XXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRI-----SSLEEANKLL 260
                       ++ +  E  IA        K++LL  +E K+ +      S L E N  L
Sbjct: 1628 RLESESAAKLAELKRKAEQKIAA------IKKQLLSQMEEKEEQYKKGTESHLSELNTKL 1681

Query: 261  EAARFEISLEHSKL----AQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSL 316
            +    E+ +   KL    + + E                 +++    C +KT  EEK S+
Sbjct: 1682 QEREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQEEADSQGCVQKT-YEEKISV 1740

Query: 317  EIANMTELTKKIE---------LLEH--LNCQIRQTNKELENKLA-------TMGTESKA 358
               N+TE  K ++         +  H  + CQ ++   +LE+  A        +G   + 
Sbjct: 1741 LQRNLTEKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKLEHAEAKQHEDQSMIGHLQEE 1800

Query: 359  VSSPSKKGSPLIS----RKSGRN---TASKMKSPWSQLSSETLNQDTDKKINKNEIAKLE 411
            +   +KK S +++    ++ G+N       +++ +  +      ++   +I + +I +L+
Sbjct: 1801 LEEKNKKYSLIVAQHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELTCQILEQKIKELD 1860

Query: 412  -MVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEH--QQHMEGPSLI-H 467
              +++      V+ E + S+ +            K T + +   E   + H+  P L+ +
Sbjct: 1861 SCLVRQKEVHRVEMEELTSKYEKLQALQQMDGRNKPTELLEENTEEKSKSHLVQPKLLSN 1920

Query: 468  VGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMI 527
            +     D+       E+ KQ+L  EI  +  KDL    K  ++++  L  E D   +  I
Sbjct: 1921 MEAQHNDLEFKLAGAEREKQKLGKEIVRLQ-KDLRMLRKEHQQELEILKKEYDQEREEKI 1979

Query: 528  KVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELH-HLSQKVAELEEEKGNLQLHLV 586
            K +    L+LK    T+    +  + N ++ +  +EL   + + + + +E +  L     
Sbjct: 1980 K-QEQEDLELKH-NSTLKQLMR--EFNTQLAQKEQELEMTIKETINKAQEVEAEL----- 2030

Query: 587  DYDSGRMIESDVYKKMIEM-ENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLA 645
              +S +   + + KK+ E  ++L  T  +   +L++++ ++  ++  LQ + +E++ K  
Sbjct: 2031 -LESHQEETNQLLKKIAEKDDDLKRTAKRYEEILDAREEEMTAKVRDLQTQLEELQKKYQ 2089

Query: 646  DISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLEN 701
               + + +     +  + L+ Q+    A K  L   I + KL +++    I +LE+
Sbjct: 2090 QKLEQEENPGNDNVTIMELQTQL----AQKTTL---ISDSKLKEQEFREQIHNLED 2138


>UniRef50_Q25893 Cluster: Liver stage antigen; n=41; Plasmodium
            falciparum|Rep: Liver stage antigen - Plasmodium
            falciparum
          Length = 1909

 Score =  146 bits (354), Expect = 4e-33
 Identities = 287/1455 (19%), Positives = 631/1455 (43%), Gaps = 113/1455 (7%)

Query: 151  IKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXX 210
            ++E+ + L   ++  + ++    DL+++   K+++ E ++                    
Sbjct: 192  LQEQQSDLEQERLAKEKLQEQQSDLEQERLAKEKLQEQQSDLEQERRAKEKLQEQQSDLE 251

Query: 211  XEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLE 270
             E   ++  + Q++ +  E   K++ Q    D+E + +    L+E    LE  R     +
Sbjct: 252  QERRAKEKLQEQQSDLEQERRAKEKLQEQQSDLEQERLAKEKLQEQQSDLEQER-RAKEK 310

Query: 271  HSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIEL 330
              +   +LEQ              L ++ +    +EK + E++  LE   + +  +K++ 
Sbjct: 311  LQEQQSDLEQERLAKEKLQEQQSDLEQERL---AKEKLQ-EQQSDLEQERLAK--EKLQG 364

Query: 331  LEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQ-- 388
             +    Q R   ++L+ + + +  +  A     ++ S L   +  +    + +S   Q  
Sbjct: 365  QQSDLEQERLAKEKLQEQQSDLEQDRLAKEKLQEQQSDLEQERLAKEKLQEQQSDLEQER 424

Query: 389  LSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTL 448
             + E L Q+    + +  +AK +  +Q    DL  +     +              K+ L
Sbjct: 425  RAKEKL-QEQQSDLEQERLAKEK--LQEQQSDLEQERRAKEKLQEQQSDLEQERRAKEKL 481

Query: 449  IAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSA 508
              Q     Q+ +    L    ++ E    +AK  E+L+++ +D  ++   K+ +++ +S 
Sbjct: 482  QEQQSDLEQERLAKEKLQEQQSDLEQ-ERLAK--EKLQEQQSDSEQERLAKEKLQEQQSD 538

Query: 509  EEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLS 568
             EQ     +++     + ++ +   K KL++ Q         SD  +E  RL +E   L 
Sbjct: 539  LEQERLAKEKLQEQQSD-LEQERLAKEKLQEQQ---------SDLEQE--RLAKE--KLQ 584

Query: 569  QKVAELEEE---KGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFD 625
            ++ ++LE+E   K  LQ    D +  R+ +    K   +  +L + RL A   L+ Q+ D
Sbjct: 585  EQQSDLEQERLAKEKLQGQQSDLEQERLAKE---KLQGQQSDLEQERL-AKEKLQEQQSD 640

Query: 626  LVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASK-KELALVIEN 684
            L QE  + ++K   ++++ +D+ + ++ +   + +   LE+  + L+  K +E    +E 
Sbjct: 641  LEQE-RLAKEK---LQEQQSDLERTKASKETLQEQQSDLEQ--ERLAKEKLQEQQSDLEQ 694

Query: 685  LKLDKEQLYGTIKDLENDK--EDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKIN-H 741
             +  KE+L     DLE ++  ++ + + Q+ +++     +KL++  ++   E  AK    
Sbjct: 695  ERRAKEKLQEQQSDLEQERRAKEKLQEQQSDLEQERRAKEKLQEQQSDLEQERRAKEKLQ 754

Query: 742  EEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQ 801
            E+QS ++       K+QE+       +S+L + +    +L+E  + +E  R + E+  +Q
Sbjct: 755  EQQSDLEQDRLAKEKLQEQ-------QSDLEQERRAKEKLQEQQSDLEQDRLAKEKLQEQ 807

Query: 802  LGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQL-LEIEHENKELQKKNQILLE 860
                 QE++        Q D    RLA     +++ E+Q  LE E   KE  ++ Q  LE
Sbjct: 808  QSDLEQERRAKEKLQEQQSDLEQERLA----KEKLQEQQSDLEQERRAKEKLQEQQSDLE 863

Query: 861  EN----QNLQISLSDMQQHYNA---LVEKANRTDLAESESTKYQTQLRDLESN--LKRIT 911
            ++    + LQ   SD++Q   A   L E+ +  +       K Q Q  DLE     K   
Sbjct: 864  QDRLAKEKLQEQQSDLEQERRAKEKLQEQQSDLEQERRAKEKLQEQQSDLEQERLAKEKL 923

Query: 912  HEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNI 971
             E Q  + Q+++  E L+ E  + +E   R K+ L E+ + ++E     + +LQE ++++
Sbjct: 924  QEQQRDLEQERRAKEKLQ-EQQSDLEQERRAKEKLQEQ-QSDLEQERLAKEKLQEQQSDL 981

Query: 972  ENLNMNVEELNKMNLELIDKHVQKQ--QTQSPDYTEQYINEINKLNALLKQKDEEIIALN 1029
            E   +  E+L +   +L  + + K+  Q Q  D  ++ + +  KL       ++E +A  
Sbjct: 982  EQERLAKEKLQEQQSDLEQERLAKEKLQGQQSDLEQERLAK-EKLQGQQSDLEQERLA-K 1039

Query: 1030 QKINNAQVSYMSMVSDYE-SKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQ 1088
            +K+   Q       SD E  +LA+   + +  + E +R++K+ L  +Q + E + L +E+
Sbjct: 1040 EKLQEQQ-------SDLEQERLAKEKLQEQQSDLEQERLAKEKLQGQQSDLEQERLAKEK 1092

Query: 1089 -DDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEE 1147
               Q  +L++ +L  E    K +G       E ++ +                  K+QE+
Sbjct: 1093 LQGQQSDLEQERLAKE----KLQGQQSDLEQERLAKEKLQGQQSDLEQERLAKE-KLQEQ 1147

Query: 1148 EEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLN 1207
            +  +++  + +E+  +  ++L++      +L+   ++L      ++E + + +S LEQ  
Sbjct: 1148 QSDLEQERLAKEKLQEQQSDLEQERRAKEKLQEQQSDLE-RTKASKETLQEQQSDLEQER 1206

Query: 1208 TENDNLLSTVAEL----RSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSA 1263
               + L    ++L    R+       Q   E   L K+ L ++++D ++ E   + +L  
Sbjct: 1207 LAKEKLQEQQSDLEQERRAKEKLQEQQSDLEQERLAKEKLQEQQSDLEQ-ERRAKEKLQE 1265

Query: 1264 FESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEIL 1323
             +S  EQ   + +   +++++    +EQ    + KLQ+++  L   QE+ A    +++  
Sbjct: 1266 QQSDLEQERRAKEKLQEQQSD----LEQERRAKEKLQEQQSDLE--QERLAK--EKLQEQ 1317

Query: 1324 RSEIEDEKVA-FXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSX 1382
            +S++E E++A                  +   E QS  + +  +   + E+ + L++   
Sbjct: 1318 QSDLEQERLAKEKLQEQQSDLEQERRAKEKLQEQQSDLEQERLAKEKLQEQQSDLEQERR 1377

Query: 1383 XXXXXXXXXXXRVND--AEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQ 1440
                          D  A+ K+ E    LE ++    +K  E    L Q     E +++Q
Sbjct: 1378 AKEKLQEQQSDLEQDRLAKEKLQEQQRDLE-QERRAKEKLQEQQSDLEQERRAKEKLQEQ 1436

Query: 1441 L--VEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITES 1498
               +E E+R ++   E++S+L   R +  E     ++  ++  + + KL +E    + + 
Sbjct: 1437 QSDLEQERRAKEKLQEQQSDLEQER-RAKEKLQEQQSDLEQERLAKEKL-QEQQRDLEQE 1494

Query: 1499 VSLNKQVAELNKALEEE---VAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQ 1555
                +++ E    LE+E     K  E Q+ LE + +    L ++  +L+   RA   K+Q
Sbjct: 1495 RRAKEKLQEQQSDLEQERRAKEKLQEQQSDLEQERLANEKLQEQQRDLEQERRA-KEKLQ 1553

Query: 1556 KHVSFASDTKQGRDE 1570
            +  S     ++ +++
Sbjct: 1554 EQQSDLEQERRAKEK 1568



 Score =  135 bits (326), Expect = 1e-29
 Identities = 258/1253 (20%), Positives = 542/1253 (43%), Gaps = 101/1253 (8%)

Query: 402  INKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTL-----------IA 450
            + +N++ K   +I+ +  D  DK+  I  +D            K+TL           +A
Sbjct: 112  LKENKLNKEGKLIEHIINDDDDKKKYIKGQDENRQEDLEEKAAKETLQGQQSDLEQERLA 171

Query: 451  QLQLEHQQ---HMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKS 507
            + +L+ QQ     E  +   +     D+ +    +E+L+++ +D  ++   K+ +++ +S
Sbjct: 172  KEKLQEQQSDSEQERLAKEKLQEQQSDLEQERLAKEKLQEQQSDLEQERLAKEKLQEQQS 231

Query: 508  AEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSD------SNKEIVRLT 561
              EQ  +  +++     + ++ +   K KL++ Q  ++   +  +      S+ E  RL 
Sbjct: 232  DLEQERRAKEKLQEQQSD-LEQERRAKEKLQEQQSDLEQERRAKEKLQEQQSDLEQERLA 290

Query: 562  EELHHLSQKVAELEEE---KGNLQLHLVDYDSGRMIESDVYKKM--IEMENLAETRLK-- 614
            +E   L ++ ++LE+E   K  LQ    D +  R+ +  + ++   +E E LA+ +L+  
Sbjct: 291  KE--KLQEQQSDLEQERRAKEKLQEQQSDLEQERLAKEKLQEQQSDLEQERLAKEKLQEQ 348

Query: 615  ---------AISLLESQKFDLVQEL----HILQQKYDEVEDKLA--DISQLQSDQVCSEI 659
                     A   L+ Q+ DL QE      + +Q+ D  +D+LA   + + QSD     +
Sbjct: 349  QSDLEQERLAKEKLQGQQSDLEQERLAKEKLQEQQSDLEQDRLAKEKLQEQQSDLEQERL 408

Query: 660  KSVHLEEQIDALSASKK------ELALVIENLKLDKEQLYGTIKDLENDK--EDIMNKLQ 711
                L+EQ   L   ++      E    +E  +L KE+L     DLE ++  ++ + + Q
Sbjct: 409  AKEKLQEQQSDLEQERRAKEKLQEQQSDLEQERLAKEKLQEQQSDLEQERRAKEKLQEQQ 468

Query: 712  NYIQENMDLTDKLEKMSAEKISELLAKIN-HEEQSKIQTQFGIDAKIQERDLYIENIESE 770
            + +++     +KL++  ++   E LAK    E+QS ++ +     K+QE+    E     
Sbjct: 469  SDLEQERRAKEKLQEQQSDLEQERLAKEKLQEQQSDLEQERLAKEKLQEQQSDSEQERLA 528

Query: 771  LSKYKSRICRLE-ESIAVMEDRRYSLERKADQLG-SYLQEKQKAYSEYTIQEDELVNRLA 828
              K + +   LE E +A  + +    + + ++L    LQE+Q    +  + +++L  + +
Sbjct: 529  KEKLQEQQSDLEQERLAKEKLQEQQSDLEQERLAKEKLQEQQSDLEQERLAKEKLQEQQS 588

Query: 829  VLMDHDRVVEKQL------LEIEHENKELQKKNQILLEE----NQNLQISLSDMQQHYNA 878
             L + +R+ +++L      LE E   KE  +  Q  LE+     + LQ   SD++Q   A
Sbjct: 589  DL-EQERLAKEKLQGQQSDLEQERLAKEKLQGQQSDLEQERLAKEKLQEQQSDLEQERLA 647

Query: 879  LVE-KANRTDLAESESTK--YQTQLRDLESN--LKRITHEHQTLIVQKKKEIEDLEIEFN 933
              + +  ++DL  ++++K   Q Q  DLE     K    E Q+ + Q+++  E L+ E  
Sbjct: 648  KEKLQEQQSDLERTKASKETLQEQQSDLEQERLAKEKLQEQQSDLEQERRAKEKLQ-EQQ 706

Query: 934  TQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHV 993
            + +E   R K+ L E+ + ++E   + + +LQE ++++E      E+L +   +L    +
Sbjct: 707  SDLEQERRAKEKLQEQ-QSDLEQERRAKEKLQEQQSDLEQERRAKEKLQEQQSDLEQDRL 765

Query: 994  QKQQTQSPDY-TEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQ 1052
             K++ Q      EQ      KL    +Q D E   L ++    Q S +      + KL +
Sbjct: 766  AKEKLQEQQSDLEQERRAKEKLQE--QQSDLEQDRLAKEKLQEQQSDLEQERRAKEKLQE 823

Query: 1053 FTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDD-QIKELKETKLTFEMNIPKTEG 1111
              + LE      +++ +Q  D +Q     + L  +Q D +   L + KL  + +  + E 
Sbjct: 824  QQSDLEQERLAKEKLQEQQSDLEQERRAKEKLQEQQSDLEQDRLAKEKLQEQQSDLEQER 883

Query: 1112 MIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQEC 1171
                   E  SD                   + +  +E +QE+    EQ  +   +LQE 
Sbjct: 884  RAKEKLQEQQSDLEQERRAKEKLQEQQSDLEQERLAKEKLQEQQRDLEQERRAKEKLQEQ 943

Query: 1172 YTKIIQLETLNTELTGHDV-VNQEQINQLKSKLEQLNTENDNLL-STVAELRSSISS--- 1226
             + + Q      +L      + QE++ + K + +Q + E + L    + E +S +     
Sbjct: 944  QSDLEQERRAKEKLQEQQSDLEQERLAKEKLQEQQSDLEQERLAKEKLQEQQSDLEQERL 1003

Query: 1227 AVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEE--TN 1284
            A ++   + ++L ++ LA+ +   Q  + +L  +  A E   EQ  D  Q    +E    
Sbjct: 1004 AKEKLQGQQSDLEQERLAKEK--LQGQQSDLEQERLAKEKLQEQQSDLEQERLAKEKLQE 1061

Query: 1285 KIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXX 1344
            +   +EQ    + KLQ ++  L   QE+ A    +++  +S++E E++A           
Sbjct: 1062 QQSDLEQERLAKEKLQGQQSDLE--QERLAK--EKLQGQQSDLEQERLAKEKLQGQQSDL 1117

Query: 1345 XXXXXXDLRTENQSYKQMQEQ-SILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVL 1403
                    + + Q     QE+ +   + E+ + L++                 +  AK  
Sbjct: 1118 EQERLAKEKLQGQQSDLEQERLAKEKLQEQQSDLEQERLAKEKLQEQQSDLEQERRAKEK 1177

Query: 1404 ELTHQLELKDSEIYQKT-HEYTITLTQRNDEFENVRQQL--VEYEKRIEDLTYEKESELA 1460
                Q +L+ ++  ++T  E    L Q     E +++Q   +E E+R ++   E++S+L 
Sbjct: 1178 LQEQQSDLERTKASKETLQEQQSDLEQERLAKEKLQEQQSDLEQERRAKEKLQEQQSDLE 1237

Query: 1461 ILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEE---VA 1517
              RL   +       +++E   +  + ++E    + +     +++ E    LE+E     
Sbjct: 1238 QERLAKEKLQEQQSDLEQERRAK--EKLQEQQSDLEQERRAKEKLQEQQSDLEQERRAKE 1295

Query: 1518 KTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDE 1570
            K  E Q+ LE + +    L ++ ++L+   R +  K+Q+  S     ++ +++
Sbjct: 1296 KLQEQQSDLEQERLAKEKLQEQQSDLE-QERLAKEKLQEQQSDLEQERRAKEK 1347



 Score =  123 bits (296), Expect = 5e-26
 Identities = 232/1064 (21%), Positives = 457/1064 (42%), Gaps = 92/1064 (8%)

Query: 212  EDTKQQMTKMQENFIAME---AEWKD-EKQRLLKDIESKDVRISSLEEANKLLEAARFEI 267
            E  ++Q + +++  +A E    +  D E++RL K  E    + S LE+     E  + + 
Sbjct: 581  EKLQEQQSDLEQERLAKEKLQGQQSDLEQERLAK--EKLQGQQSDLEQERLAKEKLQEQQ 638

Query: 268  S-LEHSKLAQE-LEQXXXXXXXXXXXXXXLAKQSIEPSCEE--KTEIEEKGSLEIANMTE 323
            S LE  +LA+E L++              L +Q  +   E   K +++E+ S ++     
Sbjct: 639  SDLEQERLAKEKLQEQQSDLERTKASKETLQEQQSDLEQERLAKEKLQEQQS-DLEQERR 697

Query: 324  LTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMK 383
              +K++  +    Q R+  ++L+ + + +  E +A     ++ S L   +  +    + +
Sbjct: 698  AKEKLQEQQSDLEQERRAKEKLQEQQSDLEQERRAKEKLQEQQSDLEQERRAKEKLQEQQ 757

Query: 384  SPWSQ--LSSETLN-QDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXX 440
            S   Q  L+ E L  Q +D +  +    KL+     L +D + KE +  ++         
Sbjct: 758  SDLEQDRLAKEKLQEQQSDLEQERRAKEKLQEQQSDLEQDRLAKEKLQEQQSDLEQERRA 817

Query: 441  XXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKD 500
                K+ L  Q     Q+ +    L        D+ +  + +E+L+++ +D  +D   K+
Sbjct: 818  ----KEKLQEQQSDLEQERLAKEKLQE---QQSDLEQERRAKEKLQEQQSDLEQDRLAKE 870

Query: 501  LIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNF----SKVSDSNKE 556
             +++ +S  EQ  +  +++     ++ + +   K KL++ Q  ++       K+ +  ++
Sbjct: 871  KLQEQQSDLEQERRAKEKLQEQQSDL-EQERRAKEKLQEQQSDLEQERLAKEKLQEQQRD 929

Query: 557  IVRLTEELHHLSQKVAELEEE---KGNLQLHLVDYDSGRMIESDVYKKM--IEMENLAET 611
            + +       L ++ ++LE+E   K  LQ    D +  R+ +  + ++   +E E LA+ 
Sbjct: 930  LEQERRAKEKLQEQQSDLEQERRAKEKLQEQQSDLEQERLAKEKLQEQQSDLEQERLAKE 989

Query: 612  RLK-----------AISLLESQKFDLVQEL----HILQQKYDEVEDKLAD--ISQLQSDQ 654
            +L+           A   L+ Q+ DL QE      +  Q+ D  +++LA   + + QSD 
Sbjct: 990  KLQEQQSDLEQERLAKEKLQGQQSDLEQERLAKEKLQGQQSDLEQERLAKEKLQEQQSDL 1049

Query: 655  VCSEIKSVHLEEQIDALSA---SKKELA---LVIENLKLDKEQLYGTIKDLEND---KED 705
                +    L+EQ   L     +K++L      +E  +L KE+L G   DLE +   KE 
Sbjct: 1050 EQERLAKEKLQEQQSDLEQERLAKEKLQGQQSDLEQERLAKEKLQGQQSDLEQERLAKEK 1109

Query: 706  IMNKLQNYIQENMDLTDKLEKMSAEKISELLAKIN-HEEQSKIQTQFGIDAKIQER--DL 762
            +  +  +  QE +   +KL+   ++   E LAK    E+QS ++ +     K+QE+  DL
Sbjct: 1110 LQGQQSDLEQERL-AKEKLQGQQSDLEQERLAKEKLQEQQSDLEQERLAKEKLQEQQSDL 1168

Query: 763  Y--------IENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYS 814
                     ++  +S+L + K+    L+E  + +E  R + E+  +Q     QE++    
Sbjct: 1169 EQERRAKEKLQEQQSDLERTKASKETLQEQQSDLEQERLAKEKLQEQQSDLEQERRAKEK 1228

Query: 815  EYTIQEDELVNRLAVLMDHDRVVEKQL-LEIEHENKELQKKNQILLEE----NQNLQISL 869
                Q D    RLA     +++ E+Q  LE E   KE  ++ Q  LE+     + LQ   
Sbjct: 1229 LQEQQSDLEQERLA----KEKLQEQQSDLEQERRAKEKLQEQQSDLEQERRAKEKLQEQQ 1284

Query: 870  SDMQQHYNA---LVEKANRTDLAESESTKYQTQLRDLESN--LKRITHEHQTLIVQKKKE 924
            SD++Q   A   L E+ +  +       K Q Q  DLE     K    E Q+ + Q+++ 
Sbjct: 1285 SDLEQERRAKEKLQEQQSDLEQERLAKEKLQEQQSDLEQERLAKEKLQEQQSDLEQERRA 1344

Query: 925  IEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKM 984
             E L+ E  + +E     K+ L E+ + ++E   + + +LQE ++++E   +  E+L + 
Sbjct: 1345 KEKLQ-EQQSDLEQERLAKEKLQEQ-QSDLEQERRAKEKLQEQQSDLEQDRLAKEKLQEQ 1402

Query: 985  --NLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSM 1042
              +LE   +  +K Q Q  D  EQ      KL       ++E  A  +K+   Q S +  
Sbjct: 1403 QRDLEQERRAKEKLQEQQSD-LEQERRAKEKLQEQQSDLEQERRA-KEKLQEQQ-SDLEQ 1459

Query: 1043 VSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTF 1102
                + KL +  + LE      +++ +Q  D +Q     + L  +Q D  +E +  +   
Sbjct: 1460 ERRAKEKLQEQQSDLEQERLAKEKLQEQQRDLEQERRAKEKLQEQQSDLEQERRAKEKLQ 1519

Query: 1103 EMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEE-EEFIQERSVLQEQS 1161
            E      +  + +  ++    D                 L+ +   +E +QE+    EQ 
Sbjct: 1520 EQQSDLEQERLANEKLQEQQRDLEQERRAKEKLQEQQSDLEQERRAKEKLQEQQSDLEQE 1579

Query: 1162 AKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQ 1205
             +   +LQE  + + Q E L  E       + EQ    K KL++
Sbjct: 1580 RRAKEKLQEQQSDLEQ-ERLAKEKLQEQQRDLEQERLAKEKLQE 1622



 Score =  119 bits (286), Expect = 8e-25
 Identities = 227/1079 (21%), Positives = 465/1079 (43%), Gaps = 90/1079 (8%)

Query: 525  NMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLH 584
            N++    N K+     +  I   +  S S+    R+ EE H     ++    EK      
Sbjct: 15   NLLIFHINGKIIKNSEKDEIIKSNLRSGSSNSRNRINEEKHEKKHVLSHNSYEKTK---- 70

Query: 585  LVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKL 644
              + ++ +  + D    M  ++N+++T  K  SLL +    + + + + + K ++ E KL
Sbjct: 71   --NNENNKFFDKDKELTMSNVKNVSQTNFK--SLLRN--LGVSENIFLKENKLNK-EGKL 123

Query: 645  ADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALV----IENLKLDKEQLYGTIKDLE 700
             +      D     IK      Q D    + KE        +E  +L KE+L     D E
Sbjct: 124  IEHIINDDDDKKKYIKGQDENRQEDLEEKAAKETLQGQQSDLEQERLAKEKLQEQQSDSE 183

Query: 701  NDK--EDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKIN-HEEQSKIQTQFGIDAKI 757
             ++  ++ + + Q+ +++     +KL++  ++   E LAK    E+QS ++ +     K+
Sbjct: 184  QERLAKEKLQEQQSDLEQERLAKEKLQEQQSDLEQERLAKEKLQEQQSDLEQERRAKEKL 243

Query: 758  QER--DL--------YIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQ 807
            QE+  DL         ++  +S+L + +    +L+E  + +E  R + E+  +Q     Q
Sbjct: 244  QEQQSDLEQERRAKEKLQEQQSDLEQERRAKEKLQEQQSDLEQERLAKEKLQEQQSDLEQ 303

Query: 808  EKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQL-LEIEHENKELQKKNQILLEE----N 862
            E++        Q D    RLA     +++ E+Q  LE E   KE  ++ Q  LE+     
Sbjct: 304  ERRAKEKLQEQQSDLEQERLA----KEKLQEQQSDLEQERLAKEKLQEQQSDLEQERLAK 359

Query: 863  QNLQISLSDMQQHYNALVE-KANRTDLAESE--STKYQTQLRDLESN--LKRITHEHQTL 917
            + LQ   SD++Q   A  + +  ++DL +      K Q Q  DLE     K    E Q+ 
Sbjct: 360  EKLQGQQSDLEQERLAKEKLQEQQSDLEQDRLAKEKLQEQQSDLEQERLAKEKLQEQQSD 419

Query: 918  IVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMN 977
            + Q+++  E L+ E  + +E     K+ L E+ + ++E   + + +LQE ++++E     
Sbjct: 420  LEQERRAKEKLQ-EQQSDLEQERLAKEKLQEQ-QSDLEQERRAKEKLQEQQSDLEQERRA 477

Query: 978  VEELNKMNLELIDKHVQKQ--QTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNA 1035
             E+L +   +L  + + K+  Q Q  D  ++ + +  KL       ++E +A  +K+   
Sbjct: 478  KEKLQEQQSDLEQERLAKEKLQEQQSDLEQERLAK-EKLQEQQSDSEQERLA-KEKLQEQ 535

Query: 1036 QVSYMSMVSDYE-SKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQ-DDQIK 1093
            Q       SD E  +LA+   + +  + E +R++K+ L  +Q + E + L +E+  +Q  
Sbjct: 536  Q-------SDLEQERLAKEKLQEQQSDLEQERLAKEKLQEQQSDLEQERLAKEKLQEQQS 588

Query: 1094 ELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQE 1153
            +L++ +L  E    K +G       E ++ +                  K+QE++  +++
Sbjct: 589  DLEQERLAKE----KLQGQQSDLEQERLAKEKLQGQQSDLEQERLAKE-KLQEQQSDLEQ 643

Query: 1154 RSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNL 1213
              + +E+  +  ++L+        L+   ++L   + + +E++ + +S LEQ     + L
Sbjct: 644  ERLAKEKLQEQQSDLERTKASKETLQEQQSDLE-QERLAKEKLQEQQSDLEQERRAKEKL 702

Query: 1214 LSTVAEL----RSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYE 1269
                ++L    R+       Q   E     K+ L ++++D ++ E   + +L   +S  E
Sbjct: 703  QEQQSDLEQERRAKEKLQEQQSDLEQERRAKEKLQEQQSDLEQ-ERRAKEKLQEQQSDLE 761

Query: 1270 QLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHL---RNLQEKYADVINQIEILRSE 1326
            Q  D +     +E      +EQ    + KLQ+++  L   R  +EK  +  + +E  R  
Sbjct: 762  Q--DRLAKEKLQEQQS--DLEQERRAKEKLQEQQSDLEQDRLAKEKLQEQQSDLEQERRA 817

Query: 1327 IE--DEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXX 1384
             E   E+ +                 DL  E ++ +++QEQ     + E  +L K     
Sbjct: 818  KEKLQEQQSDLEQERLAKEKLQEQQSDLEQERRAKEKLQEQ---QSDLEQDRLAKEKLQE 874

Query: 1385 XXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQL--V 1442
                     R   A+ K+ E    LE ++    +K  E    L Q     E +++Q   +
Sbjct: 875  QQSDLEQERR---AKEKLQEQQSDLE-QERRAKEKLQEQQSDLEQERLAKEKLQEQQRDL 930

Query: 1443 EYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLN 1502
            E E+R ++   E++S+L   R +  E     ++  ++  + + KL E+ +    E ++  
Sbjct: 931  EQERRAKEKLQEQQSDLEQER-RAKEKLQEQQSDLEQERLAKEKLQEQQSDLEQERLAKE 989

Query: 1503 KQVAELNKALEEEVA--KTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVS 1559
            K   + +   +E +A  K    Q+ LE + +    L  + ++L+   R +  K+Q+  S
Sbjct: 990  KLQEQQSDLEQERLAKEKLQGQQSDLEQERLAKEKLQGQQSDLE-QERLAKEKLQEQQS 1047



 Score = 87.0 bits (206), Expect = 4e-15
 Identities = 209/1020 (20%), Positives = 421/1020 (41%), Gaps = 79/1020 (7%)

Query: 151  IKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXX 210
            ++++  A   LQ +   +E   L  +EK+ E+   +E + +A                  
Sbjct: 845  LEQERRAKEKLQEQQSDLEQDRL-AKEKLQEQQSDLEQERRAKEKLQEQQSDLEQERRAK 903

Query: 211  XEDTKQQMTKMQENFIA--MEAEWKD-EKQRLLKDIESKDVRISSLEEANKLLEAARFEI 267
             +  +QQ    QE      ++ + +D E++R  K  E    + S LE+  +  E  + + 
Sbjct: 904  EKLQEQQSDLEQERLAKEKLQEQQRDLEQERRAK--EKLQEQQSDLEQERRAKEKLQEQQ 961

Query: 268  S-LEHSKLAQE-LEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELT 325
            S LE  +LA+E L++              L +Q  +   E   + + +G         L 
Sbjct: 962  SDLEQERLAKEKLQEQQSDLEQERLAKEKLQEQQSDLEQERLAKEKLQGQQSDLEQERLA 1021

Query: 326  K-KIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKS 384
            K K++  +    Q R   ++L+ + + +  E  A     ++ S L   +  +      +S
Sbjct: 1022 KEKLQGQQSDLEQERLAKEKLQEQQSDLEQERLAKEKLQEQQSDLEQERLAKEKLQGQQS 1081

Query: 385  PWSQ--LSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXX 442
               Q  L+ E L Q     + +  +AK ++  Q    DL ++E +  EK           
Sbjct: 1082 DLEQERLAKEKL-QGQQSDLEQERLAKEKL--QGQQSDL-EQERLAKEK----LQGQQSD 1133

Query: 443  XGKDTLIAQLQLEHQQHMEGPSLIH--VGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKD 500
              ++ L  +   E Q  +E   L    +     D+ +  + +E+L+++ +D  +    K+
Sbjct: 1134 LEQERLAKEKLQEQQSDLEQERLAKEKLQEQQSDLEQERRAKEKLQEQQSDLERTKASKE 1193

Query: 501  LIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNF----SKVSDSNKE 556
             +++ +S  EQ     +++     ++ + +   K KL++ Q  ++       K+ +   +
Sbjct: 1194 TLQEQQSDLEQERLAKEKLQEQQSDL-EQERRAKEKLQEQQSDLEQERLAKEKLQEQQSD 1252

Query: 557  IVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAI 616
            + +       L ++ ++LE+E+   +  L +  S    E    +K+ E ++  E    A 
Sbjct: 1253 LEQERRAKEKLQEQQSDLEQER-RAKEKLQEQQSDLEQERRAKEKLQEQQSDLEQERLAK 1311

Query: 617  SLLESQKFDLVQEL----HILQQKYDEVEDKLAD--ISQLQSDQVCSEIKSVHLEEQIDA 670
              L+ Q+ DL QE      + +Q+ D  +++ A   + + QSD     +    L+EQ   
Sbjct: 1312 EKLQEQQSDLEQERLAKEKLQEQQSDLEQERRAKEKLQEQQSDLEQERLAKEKLQEQQSD 1371

Query: 671  LSASKK------ELALVIENLKLDKEQLYGTIKDLENDK--EDIMNKLQNYIQENMDLTD 722
            L   ++      E    +E  +L KE+L    +DLE ++  ++ + + Q+ +++     +
Sbjct: 1372 LEQERRAKEKLQEQQSDLEQDRLAKEKLQEQQRDLEQERRAKEKLQEQQSDLEQERRAKE 1431

Query: 723  KLEKMSAEKISELLAKIN-HEEQSKIQTQFGIDAKIQER--DLYIENIESELSKYKSRIC 779
            KL++  ++   E  AK    E+QS ++ +     K+QE+  DL  E +  E  + + R  
Sbjct: 1432 KLQEQQSDLEQERRAKEKLQEQQSDLEQERRAKEKLQEQQSDLEQERLAKEKLQEQQRDL 1491

Query: 780  RLEESIAV-MEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVE 838
              E      +++++  LE++  +    LQE+Q    +  +  ++L  +   L    R  E
Sbjct: 1492 EQERRAKEKLQEQQSDLEQER-RAKEKLQEQQSDLEQERLANEKLQEQQRDLEQERRAKE 1550

Query: 839  K---QLLEIEHENK---ELQKKNQILLEEN---QNLQISLSDMQQHYNA---LVEKANRT 886
            K   Q  ++E E +   +LQ++   L +E    + LQ   SD++Q   A   L E+    
Sbjct: 1551 KLQEQQSDLEQERRAKEKLQEQQSDLEQERRAKEKLQEQQSDLEQERLAKEKLQEQQRDL 1610

Query: 887  DLAESESTKYQTQLRDLES-------NLKRITHEHQTLIVQK---KKEIEDLEIEFNTQI 936
            +       K Q Q RDLE        NL+R   EH  ++ +    + EI  +E+    + 
Sbjct: 1611 EQERLAKEKLQEQQRDLEQRKADTKKNLER-KKEHGDVLAEDLYGRLEIPAIELPSENER 1669

Query: 937  ESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVE---ELNKMNLELIDKHV 993
               I  +  L +    N       E  + E K N E++  NVE   +++K +LE   K  
Sbjct: 1670 GYYIPHQSSLPQDNRGNSR--DSKEISIIE-KTNRESITTNVEGRRDIHKGHLEE-KKDG 1725

Query: 994  QKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQF 1053
              +  Q  D +    N   +   +    D +I     +I+      +    + +  L +F
Sbjct: 1726 SIKPEQKEDKSADIQNHTLETVNISDVNDFQISKYEDEISAEYDDSLIDEEEDDEDLDEF 1785

Query: 1054 T--TKLENMEEEMQ-RVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTE 1110
                + +N ++E    + K+L D  + NE L  L    +   +EL E K+       KT+
Sbjct: 1786 KPIVQYDNFQDEENIGIYKELEDLIEKNENLDDLDEGIEKSSEELSEEKIKKGKKYEKTK 1845


>UniRef50_Q2NJC3 Cluster: Putative uncharacterized protein; n=1; Aster
            yellows witches'-broom phytoplasma AYWB|Rep: Putative
            uncharacterized protein - Aster yellows witches'-broom
            phytoplasma (strain AYWB)
          Length = 1062

 Score =  145 bits (352), Expect = 8e-33
 Identities = 198/879 (22%), Positives = 400/879 (45%), Gaps = 53/879 (6%)

Query: 472  TEDVNEIAKVQEQLKQ-ELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVK 530
            T+D N I  + ++LK+ EL  E +   +    E+LK+ +  I  L D++      + K K
Sbjct: 175  TKD-NSIKTLTDKLKEKELELEEEKNQLITAKEELKTKDNSIKTLTDKLKEKELELEKEK 233

Query: 531  SNHKLKLKQMQKTIDNFSK-VSDSNKEI-VRLTEELHHLSQKVAELEEEKGNLQLHLVDY 588
             N  +  K+  KT DN  K ++D  KE  + L EE + L     EL+ +  +++  L D 
Sbjct: 234  -NQLITAKEELKTKDNSIKTLTDKLKEKELELEEEKNQLITAKQELKTKDNSIKT-LTDK 291

Query: 589  DSGRMIESDVYK-KMIEMENLAETRLKAISLL----ESQKFDLVQELHILQQKYDEVEDK 643
               + +E +  K ++I  +   +T+  +I  L    + ++ +L +E + L     E++ K
Sbjct: 292  LKEKELELEEEKNQLITAKEELKTKDNSIKTLTDKLKEKELELEEEKNQLITAKQELKTK 351

Query: 644  LADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDK 703
               I  L +D++  + K + LEE+ + L  +K+EL     ++K   ++      +LE  K
Sbjct: 352  DNSIKTL-TDKL--KEKELELEEEKNQLITAKEELKTKDNSIKTLTDKFKEKELELEEKK 408

Query: 704  EDIMNKLQNYIQE-NMDLTDKLE-KMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERD 761
              ++   Q   +E N  +T K E K     I  L  K+  +E    + +  +    QE  
Sbjct: 409  NQLITAKQELEEEKNQLITAKEELKTKDNSIKTLTDKLKEKELELEEEKNQLITAKQELK 468

Query: 762  LYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQED 821
                +I++   K K +   LEE    +   +  LE + +QL +  +E +   +      D
Sbjct: 469  TKDNSIKTLTDKLKEKELELEEEKNQLITAKQELEEEKNQLITAKEELKTKDNSIKTLTD 528

Query: 822  ELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVE 881
            +L  +   L +    +     E+E E  +L    + L  ++ +++      ++    L E
Sbjct: 529  KLKEKELELEEKKNQLITAKQELEEEKNQLITAKEELKTKDNSIKTLTDKFKEKELELEE 588

Query: 882  KANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIR 941
            K N+   A+ E  + + QL   +  LK   +  +TL   K KE    E+E   +    I 
Sbjct: 589  KKNQLITAKQELEEEKNQLITAKEELKTKDNSIKTL-TDKFKE---KELELEEKKNQLIT 644

Query: 942  DKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSP 1001
             K+ L E  EKN + +T  E +L+   N+I+ L    ++  +  LEL +K  + Q   + 
Sbjct: 645  AKQELEE--EKN-QLITAKE-ELKTKDNSIKTL---TDKFKEKELELEEK--KNQLITAK 695

Query: 1002 DYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENME 1061
               E+  N++      LK KD  I  L  K    ++       + E K  Q  T  + +E
Sbjct: 696  QELEEEKNQLITAKEELKTKDNSIKTLTDKFKEKEL-------ELEEKKNQLITAKQELE 748

Query: 1062 EEMQRV--SKQLLDSKQHN-EELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTI 1118
            EE  ++  +K+ L +K ++ + L   ++E++ +++E K   +T +  + + +  +I++  
Sbjct: 749  EEKNQLITAKEELKTKDNSIKTLTDKLKEKELELEEKKNQLITAKQELEEEKNQLITAKE 808

Query: 1119 EPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQL 1178
            E  + D N++             L+ +++ + I  +  L+E+  +L T  +E  TK   +
Sbjct: 809  ELKTKD-NSIKTLTDKFKEKELELE-EKKNQLITAKQELEEEKNQLITAKEELKTKDNSI 866

Query: 1179 ETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELR---SSISSAVD---QRG 1232
            +TL  +L   ++  +E+ NQL +  E+L  E + L++   EL+   +SI +  D   ++ 
Sbjct: 867  KTLTDKLKEKELELEEKKNQLITAKEELEEEKNQLITAKEELKTKDNSIKTLTDKLKEKE 926

Query: 1233 FEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQV 1292
             E+ E   Q +  +E + +  ++ ++     F+ K  +L +        +        Q+
Sbjct: 927  LELEEEKNQLITAKE-ELKTKDNSIKTLTDKFKEKELELEEEKNQLITAKEELEEEKNQL 985

Query: 1293 TSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEK 1331
             + + +L+ K+  ++ L +K+ +   ++E+   E+E+EK
Sbjct: 986  ITAKVELKTKDNSIKTLTDKFKE--KELEL---ELEEEK 1019



 Score =  144 bits (349), Expect = 2e-32
 Identities = 203/1020 (19%), Positives = 449/1020 (44%), Gaps = 81/1020 (7%)

Query: 569  QKVAELEE-EKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAIS--LLESQKFD 625
            QK+ + ++  K + Q+  ++Y +      ++Y K  E E   +   K     ++  +++D
Sbjct: 38   QKILKFQKTNKMHKQIQQINYKNE--YNPNIYNKKTE-EKCEKQNPKTCQKPIIPLEEYD 94

Query: 626  LVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENL 685
             ++EL +   KY      +  I+ L+        K + ++   D L      +  + + L
Sbjct: 95   PIEELKL--SKYMSEPAVVTVINALKDKHEQLYKKHLLVKYLTDYLMTKNNSIKTLTDKL 152

Query: 686  KLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQS 745
            K  KE+L      L   KE++  K  N I+    LTDKL++   E   E    I  +E+ 
Sbjct: 153  KEKKEELEEEKNQLITAKEELKTK-DNSIKT---LTDKLKEKELELEEEKNQLITAKEEL 208

Query: 746  KIQTQF--GIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLG 803
            K +      +  K++E++L +E  +++L   K  +   + SI  + D+   L+ K  +L 
Sbjct: 209  KTKDNSIKTLTDKLKEKELELEKEKNQLITAKEELKTKDNSIKTLTDK---LKEKELELE 265

Query: 804  SYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQ 863
                +   A  E   ++    N +  L D  ++ EK+L E+E E  +L    + L  ++ 
Sbjct: 266  EEKNQLITAKQELKTKD----NSIKTLTD--KLKEKEL-ELEEEKNQLITAKEELKTKDN 318

Query: 864  NLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRIT---HEHQTLIVQ 920
            +++     +++    L E+ N+   A+ E       ++ L   LK       E +  ++ 
Sbjct: 319  SIKTLTDKLKEKELELEEEKNQLITAKQELKTKDNSIKTLTDKLKEKELELEEEKNQLIT 378

Query: 921  KKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEE 980
             K+E++  +    T +    ++K++  E  EK  + +T  + +L+E KN +      ++ 
Sbjct: 379  AKEELKTKDNSIKT-LTDKFKEKEL--ELEEKKNQLITAKQ-ELEEEKNQLITAKEELKT 434

Query: 981  LNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYM 1040
             +     L DK  +K+        E+  N++      LK KD  I  L  K+   ++   
Sbjct: 435  KDNSIKTLTDKLKEKELE-----LEEEKNQLITAKQELKTKDNSIKTLTDKLKEKEL--- 486

Query: 1041 SMVSDYESKLAQFTTKLENMEEEMQRV--SKQLLDSKQHN-EELQILVREQDDQIKELKE 1097
                + E +  Q  T  + +EEE  ++  +K+ L +K ++ + L   ++E++ +++E K 
Sbjct: 487  ----ELEEEKNQLITAKQELEEEKNQLITAKEELKTKDNSIKTLTDKLKEKELELEEKKN 542

Query: 1098 TKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVL 1157
              +T +  + + +  +I++  E  + D N++             L+ +++ + I  +  L
Sbjct: 543  QLITAKQELEEEKNQLITAKEELKTKD-NSIKTLTDKFKEKELELE-EKKNQLITAKQEL 600

Query: 1158 QEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTV 1217
            +E+  +L T  +E  TK   ++TL  +    ++  +E+ NQL +  ++L  E + L++  
Sbjct: 601  EEEKNQLITAKEELKTKDNSIKTLTDKFKEKELELEEKKNQLITAKQELEEEKNQLITAK 660

Query: 1218 AELRS---SISSAVD---QRGFEIAELWKQHL-AQREADFQKTEH-ELRVQLSAFESKYE 1269
             EL++   SI +  D   ++  E+ E   Q + A++E + +K +    + +L   ++  +
Sbjct: 661  EELKTKDNSIKTLTDKFKEKELELEEKKNQLITAKQELEEEKNQLITAKEELKTKDNSIK 720

Query: 1270 QLLDSVQSST---QEETNKIVTMEQ-VTSLQNKLQDKEEHLRNLQEKYADVINQIEILRS 1325
             L D  +      +E+ N+++T +Q +   +N+L   +E L+        + ++++    
Sbjct: 721  TLTDKFKEKELELEEKKNQLITAKQELEEEKNQLITAKEELKTKDNSIKTLTDKLKEKEL 780

Query: 1326 EIEDEK---VAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQE---QSILNINEENAQL-- 1377
            E+E++K   +                  +L+T++ S K + +   +  L + E+  QL  
Sbjct: 781  ELEEKKNQLITAKQELEEEKNQLITAKEELKTKDNSIKTLTDKFKEKELELEEKKNQLIT 840

Query: 1378 -KKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFEN 1436
             K+               +   +  +  LT +L+ K+ E+ +K ++    L    +E E 
Sbjct: 841  AKQELEEEKNQLITAKEELKTKDNSIKTLTDKLKEKELELEEKKNQ----LITAKEELEE 896

Query: 1437 VRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKIT 1496
             + QL+  ++ ++     K++ +  L  K+ E     E   +E + + +   EEL  K  
Sbjct: 897  EKNQLITAKEELKT----KDNSIKTLTDKLKEK----ELELEEEKNQLITAKEELKTKDN 948

Query: 1497 ESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQK 1556
               +L  +  E    LEEE  +    +  LE ++ +++T   E+    N ++  + K ++
Sbjct: 949  SIKTLTDKFKEKELELEEEKNQLITAKEELEEEKNQLITAKVELKTKDNSIKTLTDKFKE 1008



 Score =  140 bits (339), Expect = 3e-31
 Identities = 188/879 (21%), Positives = 396/879 (45%), Gaps = 67/879 (7%)

Query: 768  ESELSKYKSRICRLEESIAVMEDRRYSLERK---ADQLGSYLQEKQKAYSEYTIQEDELV 824
            E +LSKY S    +   I  ++D+   L +K      L  YL  K  +    T +  E  
Sbjct: 98   ELKLSKYMSEPA-VVTVINALKDKHEQLYKKHLLVKYLTDYLMTKNNSIKTLTDKLKEKK 156

Query: 825  NRLAVLMDHDRVVEKQLLEIEHENKELQ---KKNQILLEENQNLQISLSD-MQQHYNALV 880
              L    +     +++L   ++  K L    K+ ++ LEE +N  I+  + ++   N++ 
Sbjct: 157  EELEEEKNQLITAKEELKTKDNSIKTLTDKLKEKELELEEEKNQLITAKEELKTKDNSIK 216

Query: 881  EKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAI 940
               ++    E E  K + QL   +  LK   +  +TL  + K++  +LE E N Q+ +A 
Sbjct: 217  TLTDKLKEKELELEKEKNQLITAKEELKTKDNSIKTLTDKLKEKELELEEEKN-QLITAK 275

Query: 941  RDKKVLNEKYEKNIEYVTQLEAQLQEYKNNI----ENLNMNVEELNKMNLELIDKHVQKQ 996
            ++ K  +   +   + + + E +L+E KN +    E L      +  +  +L +K ++ +
Sbjct: 276  QELKTKDNSIKTLTDKLKEKELELEEEKNQLITAKEELKTKDNSIKTLTDKLKEKELELE 335

Query: 997  QTQSPDYT--EQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFT 1054
            + ++   T  ++   + N +  L  +  E+ + L ++  N  ++    +   ++ +   T
Sbjct: 336  EEKNQLITAKQELKTKDNSIKTLTDKLKEKELELEEE-KNQLITAKEELKTKDNSIKTLT 394

Query: 1055 TKLENMEEEMQRVSKQLLDSKQHNEELQ---ILVREQ----DDQIKELKETKLTFEMNIP 1107
             K +  E E++    QL+ +KQ  EE +   I  +E+    D+ IK L +     E+ + 
Sbjct: 395  DKFKEKELELEEKKNQLITAKQELEEEKNQLITAKEELKTKDNSIKTLTDKLKEKELELE 454

Query: 1108 KTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTE 1167
            + +  +I++  E  + D N++             L+ +E+ + I  +  L+E+  +L T 
Sbjct: 455  EEKNQLITAKQELKTKD-NSIKTLTDKLKEKELELE-EEKNQLITAKQELEEEKNQLITA 512

Query: 1168 LQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELR---SSI 1224
             +E  TK   ++TL  +L   ++  +E+ NQL +  ++L  E + L++   EL+   +SI
Sbjct: 513  KEELKTKDNSIKTLTDKLKEKELELEEKKNQLITAKQELEEEKNQLITAKEELKTKDNSI 572

Query: 1225 SSAVD---QRGFEIAELWKQHL-AQREADFQKTE-HELRVQLSAFESKYEQLLDSVQS-- 1277
             +  D   ++  E+ E   Q + A++E + +K +    + +L   ++  + L D  +   
Sbjct: 573  KTLTDKFKEKELELEEKKNQLITAKQELEEEKNQLITAKEELKTKDNSIKTLTDKFKEKE 632

Query: 1278 -STQEETNKIVTMEQ-VTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEK---V 1332
               +E+ N+++T +Q +   +N+L   +E L+        + ++ +    E+E++K   +
Sbjct: 633  LELEEKKNQLITAKQELEEEKNQLITAKEELKTKDNSIKTLTDKFKEKELELEEKKNQLI 692

Query: 1333 AFXXXXXXXXXXXXXXXXDLRTENQSYKQMQE---QSILNINEENAQL---KKSSXXXXX 1386
                              +L+T++ S K + +   +  L + E+  QL   K+       
Sbjct: 693  TAKQELEEEKNQLITAKEELKTKDNSIKTLTDKFKEKELELEEKKNQLITAKQELEEEKN 752

Query: 1387 XXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFEN----VRQQLV 1442
                    +   +  +  LT +L+ K+ E+ +K ++  IT  Q  +E +N     +++L 
Sbjct: 753  QLITAKEELKTKDNSIKTLTDKLKEKELELEEKKNQ-LITAKQELEEEKNQLITAKEELK 811

Query: 1443 EYEKRIEDLTYE-KESELAILRLKMHENANHYETMQKESEIERVKLI---EELNVKITES 1498
              +  I+ LT + KE E     L++ E  N   T ++E E E+ +LI   EEL  K    
Sbjct: 812  TKDNSIKTLTDKFKEKE-----LELEEKKNQLITAKQELEEEKNQLITAKEELKTKDNSI 866

Query: 1499 VSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKI-QKH 1557
             +L  ++ E    LEE+  +    +  LE ++ +++T  +E+    N ++  + K+ +K 
Sbjct: 867  KTLTDKLKEKELELEEKKNQLITAKEELEEEKNQLITAKEELKTKDNSIKTLTDKLKEKE 926

Query: 1558 VSFASDTKQ--GRDEQL---DNTMNKELLDAVPRAELDL 1591
            +    +  Q     E+L   DN++ K L D     EL+L
Sbjct: 927  LELEEEKNQLITAKEELKTKDNSI-KTLTDKFKEKELEL 964



 Score =  129 bits (311), Expect = 7e-28
 Identities = 207/882 (23%), Positives = 383/882 (43%), Gaps = 71/882 (8%)

Query: 151  IKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXX 210
            +K KDN++  L  K+K  E   L+L+E   EK+Q+I AK +  T                
Sbjct: 173  LKTKDNSIKTLTDKLKEKE---LELEE---EKNQLITAKEELKTKDNSIKTLTDKLKEKE 226

Query: 211  XEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAAR------ 264
             E  K+   K Q      E + KD   + L D + K+  +   EE N+L+ A +      
Sbjct: 227  LELEKE---KNQLITAKEELKTKDNSIKTLTD-KLKEKELELEEEKNQLITAKQELKTKD 282

Query: 265  -----FEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEK-TEIEEKGSLEI 318
                     L+  +L  E E+               + +++    +EK  E+EE+ +  I
Sbjct: 283  NSIKTLTDKLKEKELELEEEKNQLITAKEELKTKDNSIKTLTDKLKEKELELEEEKNQLI 342

Query: 319  ANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNT 378
                EL  K   ++ L  ++++   ELE +   + T  + + +       L  +   +  
Sbjct: 343  TAKQELKTKDNSIKTLTDKLKEKELELEEEKNQLITAKEELKTKDNSIKTLTDKFKEKEL 402

Query: 379  ASKMKSPWSQLSSETLNQDTDKKIN-KNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXX 437
              + K      + + L ++ ++ I  K E+   +  I++L   L +KE  + E+      
Sbjct: 403  ELEEKKNQLITAKQELEEEKNQLITAKEELKTKDNSIKTLTDKLKEKELELEEEKNQLIT 462

Query: 438  XXXXXXGKDTLIAQL-----QLEHQQHMEGPSLIHVGTN-TEDVNEIAKVQEQLKQELND 491
                   KD  I  L     + E +   E   LI       E+ N++   +E+LK     
Sbjct: 463  AKQELKTKDNSIKTLTDKLKEKELELEEEKNQLITAKQELEEEKNQLITAKEELK----- 517

Query: 492  EIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSK-V 550
              KD ++K L +KLK  E ++ +  +++  A K  ++ + N  +  K+  KT DN  K +
Sbjct: 518  -TKDNSIKTLTDKLKEKELELEEKKNQLITA-KQELEEEKNQLITAKEELKTKDNSIKTL 575

Query: 551  SDSNKE-IVRLTEELHHLSQKVAELEEEKGNL---QLHLVDYDSGRMIESDVYK-KMIEM 605
            +D  KE  + L E+ + L     ELEEEK  L   +  L   D+     +D +K K +E+
Sbjct: 576  TDKFKEKELELEEKKNQLITAKQELEEEKNQLITAKEELKTKDNSIKTLTDKFKEKELEL 635

Query: 606  ENLAETRLKAISLLESQKFDLV---QELHILQQKYDEVEDKLADISQLQSDQVCSEIKSV 662
            E      + A   LE +K  L+   +EL         + DK  +  +L+ ++  +++ + 
Sbjct: 636  EEKKNQLITAKQELEEEKNQLITAKEELKTKDNSIKTLTDKFKE-KELELEEKKNQLITA 694

Query: 663  --HLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQE-NMD 719
               LEE+ + L  +K+EL     ++K   ++      +LE  K  ++   Q   +E N  
Sbjct: 695  KQELEEEKNQLITAKEELKTKDNSIKTLTDKFKEKELELEEKKNQLITAKQELEEEKNQL 754

Query: 720  LTDKLE-KMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRI 778
            +T K E K     I  L  K+  +E    + +  +    QE    +E  +++L   K  +
Sbjct: 755  ITAKEELKTKDNSIKTLTDKLKEKELELEEKKNQLITAKQE----LEEEKNQLITAKEEL 810

Query: 779  CRLEESIAVMED----RRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNR-LAVLMDH 833
               + SI  + D    +   LE K +QL +  QE ++  ++    ++EL  +  ++    
Sbjct: 811  KTKDNSIKTLTDKFKEKELELEEKKNQLITAKQELEEEKNQLITAKEELKTKDNSIKTLT 870

Query: 834  DRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESES 893
            D++ EK+ LE+E +  +L    + L EE   L  +  +++   N++    ++    E E 
Sbjct: 871  DKLKEKE-LELEEKKNQLITAKEELEEEKNQLITAKEELKTKDNSIKTLTDKLKEKELEL 929

Query: 894  TKYQTQLRDLESNLKRITHEHQTLIVQ-KKKEIEDLEIEFNTQIESAIRDKKVLNEKYEK 952
             + + QL   +  LK   +  +TL  + K+KE+E LE E N  I +    K+ L E  EK
Sbjct: 930  EEEKNQLITAKEELKTKDNSIKTLTDKFKEKELE-LEEEKNQLITA----KEELEE--EK 982

Query: 953  NIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQ 994
            N + +T  + +L+   N+I+ L    +E  ++ LEL ++  Q
Sbjct: 983  N-QLIT-AKVELKTKDNSIKTLTDKFKE-KELELELEEEKNQ 1021



 Score =  128 bits (309), Expect = 1e-27
 Identities = 216/933 (23%), Positives = 407/933 (43%), Gaps = 99/933 (10%)

Query: 305  EEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELE---NKLATMGTESKAVSS 361
            E+K E+EE+ +  I    EL  K   ++ L  ++++   ELE   N+L T   E K   +
Sbjct: 154  EKKEELEEEKNQLITAKEELKTKDNSIKTLTDKLKEKELELEEEKNQLITAKEELKTKDN 213

Query: 362  PSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDL 421
              K  +  +  K       K K+       E   +D   K   +++ + E+ ++     L
Sbjct: 214  SIKTLTDKLKEK--ELELEKEKNQLITAKEELKTKDNSIKTLTDKLKEKELELEEEKNQL 271

Query: 422  VDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKV 481
            +  +  +  KD            K     +L+LE +++    +   + T    +  +   
Sbjct: 272  ITAKQELKTKDNSIKTLTDKLKEK-----ELELEEEKNQLITAKEELKTKDNSIKTLTDK 326

Query: 482  QEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQ 541
             ++ + EL +E   +      ++LK+ +  I  L D++      + + K N  +  K+  
Sbjct: 327  LKEKELELEEEKNQLITAK--QELKTKDNSIKTLTDKLKEKELELEEEK-NQLITAKEEL 383

Query: 542  KTIDNFSK-VSDSNKE-IVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVY 599
            KT DN  K ++D  KE  + L E+ + L     ELEEEK      L+        + +  
Sbjct: 384  KTKDNSIKTLTDKFKEKELELEEKKNQLITAKQELEEEKN----QLITAKEELKTKDNSI 439

Query: 600  KKMIEMENLAETRLKAISLLESQKFDLV---QELHILQQKYDEVEDKLADISQLQSDQVC 656
            K +   + L E  L+    LE +K  L+   QEL         + DKL +          
Sbjct: 440  KTL--TDKLKEKELE----LEEEKNQLITAKQELKTKDNSIKTLTDKLKE---------- 483

Query: 657  SEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQE 716
               K + LEE+ + L  +K+EL      L   KE+L    K  +N  + + +KL+   ++
Sbjct: 484  ---KELELEEEKNQLITAKQELEEEKNQLITAKEEL----KTKDNSIKTLTDKLK---EK 533

Query: 717  NMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKS 776
             ++L +K  ++   K  EL      EE++++     I AK +E      +I++   K+K 
Sbjct: 534  ELELEEKKNQLITAK-QEL-----EEEKNQL-----ITAK-EELKTKDNSIKTLTDKFKE 581

Query: 777  RICRLEESIAVMEDRRYSLERKADQLGSYLQE-KQKAYSEYTIQEDELVNRLAVLMDHDR 835
            +   LEE    +   +  LE + +QL +  +E K K  S  T+ +      L +    ++
Sbjct: 582  KELELEEKKNQLITAKQELEEEKNQLITAKEELKTKDNSIKTLTDKFKEKELELEEKKNQ 641

Query: 836  VV-EKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESEST 894
            ++  KQ LE E +N+ +  K ++  ++N +++      ++    L EK N+   A+ E  
Sbjct: 642  LITAKQELE-EEKNQLITAKEELKTKDN-SIKTLTDKFKEKELELEEKKNQLITAKQELE 699

Query: 895  KYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNI 954
            + + QL   +  LK   +  +TL   K KE    E+E   +    I  K+ L E  EKN 
Sbjct: 700  EEKNQLITAKEELKTKDNSIKTL-TDKFKE---KELELEEKKNQLITAKQELEE--EKN- 752

Query: 955  EYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKL 1014
            + +T  E +L+   N+I+ L    ++L +  LEL +K  + Q   +    E+  N++   
Sbjct: 753  QLITAKE-ELKTKDNSIKTL---TDKLKEKELELEEK--KNQLITAKQELEEEKNQLITA 806

Query: 1015 NALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDS 1074
               LK KD  I  L  K    ++       + E K  Q  T  + +EEE      QL+ +
Sbjct: 807  KEELKTKDNSIKTLTDKFKEKEL-------ELEEKKNQLITAKQELEEE----KNQLITA 855

Query: 1075 KQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXX 1134
            K   EEL    + +D+ IK L +     E+ + + +  +I++  E + ++ N +      
Sbjct: 856  K---EEL----KTKDNSIKTLTDKLKEKELELEEKKNQLITAK-EELEEEKNQLITAKEE 907

Query: 1135 XXXXXXXLKVQEEEEFIQERSV-LQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQ 1193
                   +K   ++  ++E+ + L+E+  +L T  +E  TK   ++TL  +    ++  +
Sbjct: 908  LKTKDNSIKTLTDK--LKEKELELEEEKNQLITAKEELKTKDNSIKTLTDKFKEKELELE 965

Query: 1194 EQINQLKSKLEQLNTENDNLLSTVAELRSSISS 1226
            E+ NQL +  E+L  E + L++   EL++  +S
Sbjct: 966  EEKNQLITAKEELEEEKNQLITAKVELKTKDNS 998



 Score =  120 bits (290), Expect = 3e-25
 Identities = 189/869 (21%), Positives = 369/869 (42%), Gaps = 62/869 (7%)

Query: 92   ESLANTLKQKEILMEKIKQYKELSKRSSTT---IVRXXXXXXXXXXXXXXXQLGDVTHLS 148
            ++L + LK+KE+ +E+ K     +K    T    ++               +   +    
Sbjct: 181  KTLTDKLKEKELELEEEKNQLITAKEELKTKDNSIKTLTDKLKEKELELEKEKNQLITAK 240

Query: 149  NTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXX 208
              +K KDN++  L  K+K  E   L+L+E   EK+Q+I AK +  T              
Sbjct: 241  EELKTKDNSIKTLTDKLKEKE---LELEE---EKNQLITAKQELKT-------------- 280

Query: 209  XXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEIS 268
                  K    K++E     E E ++EK +L+   E    + +S++     L+    E+ 
Sbjct: 281  -KDNSIKTLTDKLKEK----ELELEEEKNQLITAKEELKTKDNSIKTLTDKLKEKELELE 335

Query: 269  LEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLE-----IANMTE 323
             E ++L    ++              L ++ +E   E+   I  K  L+     I  +T+
Sbjct: 336  EEKNQLITAKQELKTKDNSIKTLTDKLKEKELELEEEKNQLITAKEELKTKDNSIKTLTD 395

Query: 324  LTKKIEL-LEHLNCQIRQTNKELE---NKLATMGTESKAVSSPSKKGSPLISRKSGRNTA 379
              K+ EL LE    Q+    +ELE   N+L T   E K   +  K  +  +  K      
Sbjct: 396  KFKEKELELEEKKNQLITAKQELEEEKNQLITAKEELKTKDNSIKTLTDKLKEK--ELEL 453

Query: 380  SKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXX 439
             + K+       E   +D   K   +++ + E+ ++     L+  +  + E+        
Sbjct: 454  EEEKNQLITAKQELKTKDNSIKTLTDKLKEKELELEEEKNQLITAKQELEEEKNQLITAK 513

Query: 440  XXXXGKDTLIAQL--QLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVN 497
                 KD  I  L  +L+ ++         + T  +++ E        K+EL  + KD +
Sbjct: 514  EELKTKDNSIKTLTDKLKEKELELEEKKNQLITAKQELEEEKNQLITAKEEL--KTKDNS 571

Query: 498  VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSK-VSDSNKE 556
            +K L +K K  E ++ +  +++  A K  ++ + N  +  K+  KT DN  K ++D  KE
Sbjct: 572  IKTLTDKFKEKELELEEKKNQLITA-KQELEEEKNQLITAKEELKTKDNSIKTLTDKFKE 630

Query: 557  -IVRLTEELHHLSQKVAELEEEKGNL---QLHLVDYDSGRMIESDVYK-KMIEMENLAET 611
              + L E+ + L     ELEEEK  L   +  L   D+     +D +K K +E+E     
Sbjct: 631  KELELEEKKNQLITAKQELEEEKNQLITAKEELKTKDNSIKTLTDKFKEKELELEEKKNQ 690

Query: 612  RLKAISLLESQKFDLV---QELHILQQKYDEVEDKLADISQLQSDQVCSEIKSV--HLEE 666
             + A   LE +K  L+   +EL         + DK  +  +L+ ++  +++ +    LEE
Sbjct: 691  LITAKQELEEEKNQLITAKEELKTKDNSIKTLTDKFKE-KELELEEKKNQLITAKQELEE 749

Query: 667  QIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQE-NMDLTDKLE 725
            + + L  +K+EL     ++K   ++L     +LE  K  ++   Q   +E N  +T K E
Sbjct: 750  EKNQLITAKEELKTKDNSIKTLTDKLKEKELELEEKKNQLITAKQELEEEKNQLITAKEE 809

Query: 726  -KMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEES 784
             K     I  L  K   +E    + +  +    QE +     + +   + K++   ++  
Sbjct: 810  LKTKDNSIKTLTDKFKEKELELEEKKNQLITAKQELEEEKNQLITAKEELKTKDNSIKTL 869

Query: 785  IAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNR-LAVLMDHDRVVEKQLLE 843
               ++++   LE K +QL +  +E ++  ++    ++EL  +  ++    D++ EK+ LE
Sbjct: 870  TDKLKEKELELEEKKNQLITAKEELEEEKNQLITAKEELKTKDNSIKTLTDKLKEKE-LE 928

Query: 844  IEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDL 903
            +E E  +L    + L  ++ +++      ++    L E+ N+   A+ E  + + QL   
Sbjct: 929  LEEEKNQLITAKEELKTKDNSIKTLTDKFKEKELELEEEKNQLITAKEELEEEKNQLITA 988

Query: 904  ESNLKRITHEHQTLIVQ-KKKEIEDLEIE 931
            +  LK   +  +TL  + K+KE+E LE+E
Sbjct: 989  KVELKTKDNSIKTLTDKFKEKELE-LELE 1016



 Score = 93.9 bits (223), Expect = 3e-17
 Identities = 139/700 (19%), Positives = 301/700 (43%), Gaps = 71/700 (10%)

Query: 92   ESLANTLKQKEILMEKIKQYKELSKRSSTT---IVRXXXXXXXXXXXXXXXQLGDVTHLS 148
            ++L + LK+KE+ +E+ K     +K    T    ++               +   +    
Sbjct: 356  KTLTDKLKEKELELEEEKNQLITAKEELKTKDNSIKTLTDKFKEKELELEEKKNQLITAK 415

Query: 149  NTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXX 208
              ++E+ N L   + ++K  + +I  L +K+ EK+  +E +                   
Sbjct: 416  QELEEEKNQLITAKEELKTKDNSIKTLTDKLKEKELELEEEKNQLITAKQELKTKDNSIK 475

Query: 209  XXXEDTKQQMTKMQEN---FIAMEAEWKDEKQRLL---KDIESKDVRISSL--------- 253
               +  K++  +++E     I  + E ++EK +L+   +++++KD  I +L         
Sbjct: 476  TLTDKLKEKELELEEEKNQLITAKQELEEEKNQLITAKEELKTKDNSIKTLTDKLKEKEL 535

Query: 254  --EEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEE----- 306
              EE    L  A+ E+  E ++L    E+                ++ +E   ++     
Sbjct: 536  ELEEKKNQLITAKQELEEEKNQLITAKEELKTKDNSIKTLTDKFKEKELELEEKKNQLIT 595

Query: 307  -KTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKK 365
             K E+EE+ +  I    EL  K   ++ L  + ++   ELE K   + T  + +    +K
Sbjct: 596  AKQELEEEKNQLITAKEELKTKDNSIKTLTDKFKEKELELEEKKNQLITAKQELE--EEK 653

Query: 366  GSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKE 425
               + +++  +   + +K+    L+ +   ++ + +  KN++   +  ++     L+  +
Sbjct: 654  NQLITAKEELKTKDNSIKT----LTDKFKEKELELEEKKNQLITAKQELEEEKNQLITAK 709

Query: 426  YVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTN-TEDVNEIAKVQEQ 484
              +  KD            K     +L+LE +++     LI       E+ N++   +E+
Sbjct: 710  EELKTKDNSIKTLTDKFKEK-----ELELEEKKN----QLITAKQELEEEKNQLITAKEE 760

Query: 485  LKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTI 544
            LK       KD ++K L +KLK  E ++ +  +++  A K  ++ + N  +  K+  KT 
Sbjct: 761  LK------TKDNSIKTLTDKLKEKELELEEKKNQLITA-KQELEEEKNQLITAKEELKTK 813

Query: 545  DNFSK-VSDSNKE-IVRLTEELHHLSQKVAELEEEKGNL-----QLHLVDYDSGRMIESD 597
            DN  K ++D  KE  + L E+ + L     ELEEEK  L     +L   D +S + +   
Sbjct: 814  DNSIKTLTDKFKEKELELEEKKNQLITAKQELEEEKNQLITAKEELKTKD-NSIKTLTDK 872

Query: 598  VYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQK-------YDEVEDKLADISQL 650
            + +K +E+E      + A   LE +K  L+     L+ K        D++++K  ++ + 
Sbjct: 873  LKEKELELEEKKNQLITAKEELEEEKNQLITAKEELKTKDNSIKTLTDKLKEKELELEEE 932

Query: 651  QSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMN-K 709
            ++  + ++ +    +  I  L+   KE  L +E    +K QL    ++LE +K  ++  K
Sbjct: 933  KNQLITAKEELKTKDNSIKTLTDKFKEKELELEE---EKNQLITAKEELEEEKNQLITAK 989

Query: 710  LQNYIQEN--MDLTDKLEKMSAE-KISELLAKINHEEQSK 746
            ++   ++N    LTDK ++   E ++ E   ++N+  ++K
Sbjct: 990  VELKTKDNSIKTLTDKFKEKELELELEEEKNQLNYSHKNK 1029


>UniRef50_A0DBE4 Cluster: Chromosome undetermined scaffold_44, whole
            genome shotgun sequence; n=2; Paramecium tetraurelia|Rep:
            Chromosome undetermined scaffold_44, whole genome shotgun
            sequence - Paramecium tetraurelia
          Length = 1155

 Score =  145 bits (352), Expect = 8e-33
 Identities = 230/1157 (19%), Positives = 521/1157 (45%), Gaps = 104/1157 (8%)

Query: 212  EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271
            E  +QQ   +Q+    +  E+KD + ++LK+IE   ++ + L++ N+ L +   E   + 
Sbjct: 38   EQGQQQNLDLQKENERITNEFKDRETKMLKEIEQVKLQYAELQKENERLIS---EFKDKE 94

Query: 272  SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELL 331
            +KL Q++E               L K   +    E  +I++K +LEI N+ +  + +   
Sbjct: 95   TKLLQDIEN-----QKQQNQQLILGK---DMQGNELLQIQQKLNLEIDNLKQQIQNLN-- 144

Query: 332  EHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSS 391
            + L  Q +Q +++ + K   +  E K +    +K +  ++ +   N    ++    ++  
Sbjct: 145  DQLKLQQQQFDEKEKQKNKEI-EELKLLHVQLEKQNETLTNEFKDNETKMLQ----EIEH 199

Query: 392  ETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQ 451
            + L Q   ++ N+  +++L+     + K++ +++  +   +            KD  I  
Sbjct: 200  QKLQQLQFQRENEQLMSELKDRENKMLKEIENEK--LQNLEIQKENERLRNEFKDKEIKL 257

Query: 452  LQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQ 511
            LQ    Q  +   LI +G + +  NE+ ++Q++L  E+ D +K   +++L ++LK  ++Q
Sbjct: 258  LQDIENQKQQNQQLI-LGKDMQG-NELLQIQQKLNLEI-DNLKQ-QIQNLNDQLKLQQQQ 313

Query: 512  ITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKV 571
                 DE     K   K K   +LKL  +Q  + N +  ++   +  ++  ++ HL+ ++
Sbjct: 314  F----DE-----KEKQKNKEIEELKLLHVQLELQNETLTNEFKDKETKMILDIDHLTLQL 364

Query: 572  AELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELH 631
             +L++ KGN +L    + + + +  ++    + ++   +     I+ L  Q+  L +E+ 
Sbjct: 365  -QLKDTKGN-EL----FQTQQKLNLELENIQLSLQQQQQQHDVKINDLVQQQDQLNKEIT 418

Query: 632  ILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLE-EQIDA-LSASKKELALVI-ENLKLD 688
              +Q   + ED++  ++   +D++  +IK    E  Q+   LS    +    + EN  L 
Sbjct: 419  SYKQLTSQKEDQINQLTN-NNDELSVQIKGKENEINQLQQNLSVITNDYQKSLKENENLT 477

Query: 689  KEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQ 748
            KE+L    + LEN      N +Q+   E   L ++ +     ++++L  +I+  +Q+   
Sbjct: 478  KEKLEYEAQLLEN-----KNLIQSMQHEKEQLQNEHQLNKDNQLNDLQTQISQLQQTVTS 532

Query: 749  TQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRR--YSLERKADQLGSYL 806
             Q  I A  ++++L  +N   +L +   +I +L   I  ME++R  + L  +  Q     
Sbjct: 533  QQSQI-ATDKDQNLIQQN---KLQEQNVQIQQLTVQIQNMEEQRNEFKLNNQIFQNLKIK 588

Query: 807  QEKQKAYSEYTIQEDELVNRLAVL-MDHDRVVEKQLLEIEHENKELQKKNQILLEENQNL 865
                K ++     + ++ N  ++  +   ++ E Q L+  H+  +L   N  L+EEN + 
Sbjct: 589  YVNNKLHNNQYPFKKQIKNYKSIRPIQSSKISEIQALQSAHQ--DLNIANNKLIEENNSF 646

Query: 866  QISLSDMQQHYNAL-----VEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQ 920
            QI+   +    N L     +EK     ++E ++ +  +Q+  L   + ++  E Q L V 
Sbjct: 647  QINHDQIAIEINNLQEQCRIEKETNQKISE-QNQQLSSQIEQLNEEINKLVKERQQLEVT 705

Query: 921  KKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQ-LEAQLQEYKNNIENLNMNVE 979
            +K++  + + E N Q+ + I+++KV  + Y + +E   + LE Q+ + +   +  N  +E
Sbjct: 706  QKQDHNNQQDELN-QL-NQIQEEKVNLQNYNEKLENTNKHLEEQIFQLQQQSQAQNTLLE 763

Query: 980  ELNKM--NLELIDKHVQKQQTQSPD---YTEQYINEINKLN-ALLKQKDEEIIALNQKIN 1033
            E  ++  +L++ ++ ++ Q  Q  +     ++ IN IN  N  L+ +K+ E  +  +   
Sbjct: 764  EKEQLINSLKMANEQIESQLLQDQNKQQEKDECINSINLENKKLINEKELEQNSFEEHNK 823

Query: 1034 NAQVSY-------MSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVR 1086
              ++ +       +++++  + ++ Q   K++  E   +   +Q+ + K+H + L+   +
Sbjct: 824  QDKLEFENQLNQDVTLIAQLQEEVNQQNHKIQQYENNEKNYQQQIEELKEHIQNLEDFSQ 883

Query: 1087 EQDDQIKEL--KETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKV 1144
              ++ I E   KE +L  E+   K E   +S       D                  L+ 
Sbjct: 884  VSENHISEQQEKEQQLIKELEALKLEYEHLSQQNSSFKDQVEQFQLQNEQSTHKQTLLEN 943

Query: 1145 QEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLE 1204
            + +E        LQ+Q   L   + + Y + I L  +  E     ++  E+I++ K++LE
Sbjct: 944  EIKE--------LQQQQTDLQNNIHQ-YEEKINLLQIEREQDQTKLMEAEEISKQKTELE 994

Query: 1205 -QLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSA 1263
             Q+  +ND     +  L   +    D+   E     K  + Q++ D +  +++++  L  
Sbjct: 995  KQIKHQND----AIQNLCQQVGLLEDEHPNEYIATQKAKMIQQQKDIENLKNDIK-NLQQ 1049

Query: 1264 FESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRN------LQEKYADVI 1317
               KY++         Q+E  +   +EQ++ L N   +  E ++       + ++Y   I
Sbjct: 1050 EIKKYQE--KEALIKIQKEKLERKYLEQISELSNHQDEMFEQIKEWRSKALMSDEYLKKI 1107

Query: 1318 NQIEILRSEIEDEKVAF 1334
              +E+     +D+ V++
Sbjct: 1108 KDLEMTLKFKQDQLVSY 1124



 Score =  117 bits (281), Expect = 3e-24
 Identities = 225/1155 (19%), Positives = 495/1155 (42%), Gaps = 123/1155 (10%)

Query: 502  IEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLT 561
            I++ K  E+ I +   + +    N I+      L L++  + I N  K  ++     ++ 
Sbjct: 13   IQQQKENEKFINEFKGK-EIQMLNEIEQGQQQNLDLQKENERITNEFKDRET-----KML 66

Query: 562  EELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLES 621
            +E+  +  + AEL++E   L     D ++ ++++    +K    + +    ++   LL+ 
Sbjct: 67   KEIEQVKLQYAELQKENERLISEFKDKET-KLLQDIENQKQQNQQLILGKDMQGNELLQI 125

Query: 622  QKFDLVQELHILQQKYDEVEDKLA------DISQLQSDQVCSEIKSVH--LEEQIDALSA 673
            Q+  L  E+  L+Q+   + D+L       D  + Q ++   E+K +H  LE+Q + L+ 
Sbjct: 126  QQ-KLNLEIDNLKQQIQNLNDQLKLQQQQFDEKEKQKNKEIEELKLLHVQLEKQNETLTN 184

Query: 674  SKKE----LALVIENLKL-------DKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTD 722
              K+    +   IE+ KL       + EQL   +KD EN    ++ +++N   +N+++  
Sbjct: 185  EFKDNETKMLQEIEHQKLQQLQFQRENEQLMSELKDRENK---MLKEIENEKLQNLEIQK 241

Query: 723  KLEKMSAE---KISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRIC 779
            + E++  E   K  +LL  I +++Q   Q   G D +  E     + +  E+   K +I 
Sbjct: 242  ENERLRNEFKDKEIKLLQDIENQKQQNQQLILGKDMQGNELLQIQQKLNLEIDNLKQQIQ 301

Query: 780  RLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLA-----VLMDHD 834
             L + + + + +    + K  Q    ++E +  + +  +Q + L N        +++D D
Sbjct: 302  NLNDQLKLQQQQ---FDEKEKQKNKEIEELKLLHVQLELQNETLTNEFKDKETKMILDID 358

Query: 835  RVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHY----NALVEK-------- 882
             +  +  L+ + +  EL +  Q L  E +N+Q+SL   QQ +    N LV++        
Sbjct: 359  HLTLQLQLK-DTKGNELFQTQQKLNLELENIQLSLQQQQQQHDVKINDLVQQQDQLNKEI 417

Query: 883  -----------------ANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLI------V 919
                              N  D    +    + ++  L+ NL  IT+++Q  +       
Sbjct: 418  TSYKQLTSQKEDQINQLTNNNDELSVQIKGKENEINQLQQNLSVITNDYQKSLKENENLT 477

Query: 920  QKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIE-YVTQLEAQLQEYKNNIENLNMNV 978
            ++K E E   +E    I+S   +K+ L  +++ N +  +  L+ Q+ + +  + +    +
Sbjct: 478  KEKLEYEAQLLENKNLIQSMQHEKEQLQNEHQLNKDNQLNDLQTQISQLQQTVTSQQSQI 537

Query: 979  EELNKMNL----ELIDKHVQKQQ-TQSPDYTEQYINEINKLNALLKQKDEEIIALNQKIN 1033
                  NL    +L +++VQ QQ T      E+  NE  KLN  + Q + +I  +N K++
Sbjct: 538  ATDKDQNLIQQNKLQEQNVQIQQLTVQIQNMEEQRNEF-KLNNQIFQ-NLKIKYVNNKLH 595

Query: 1034 NAQVSYMSMVSDYESKLAQFTTKLENMEE-EMQRVSKQLLDSK--QHNEELQILVREQDD 1090
            N Q  +   + +Y+S     ++K+  ++  +       + ++K  + N   QI   +   
Sbjct: 596  NNQYPFKKQIKNYKSIRPIQSSKISEIQALQSAHQDLNIANNKLIEENNSFQINHDQIAI 655

Query: 1091 QIKELKET-KLTFEMNIPKTE-GMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEE 1148
            +I  L+E  ++  E N   +E    +SS IE ++++ N +                 +++
Sbjct: 656  EINNLQEQCRIEKETNQKISEQNQQLSSQIEQLNEEINKLVKERQQLEVTQKQDHNNQQD 715

Query: 1149 EF-----IQERSV-LQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSK 1202
            E      IQE  V LQ  + KL    +    +I QL+  +          ++ IN LK  
Sbjct: 716  ELNQLNQIQEEKVNLQNYNEKLENTNKHLEEQIFQLQQQSQAQNTLLEEKEQLINSLKMA 775

Query: 1203 LEQLNTE---NDNLLSTVAELRSSIS----SAVDQRGFEIAELWKQHLAQREADFQKTEH 1255
             EQ+ ++   + N      E  +SI+      ++++  E    +++H  Q + +F+   +
Sbjct: 776  NEQIESQLLQDQNKQQEKDECINSINLENKKLINEKELE-QNSFEEHNKQDKLEFENQLN 834

Query: 1256 ELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQ----VTSLQNKLQDKEEHLRNLQE 1311
            +    ++  + +  Q    +Q     E N    +E+    + +L++  Q  E H+   QE
Sbjct: 835  QDVTLIAQLQEEVNQQNHKIQQYENNEKNYQQQIEELKEHIQNLEDFSQVSENHISEQQE 894

Query: 1312 KYADVINQIEILRSEIE---DEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSIL 1368
            K   +I ++E L+ E E    +  +F                         K++Q+Q   
Sbjct: 895  KEQQLIKELEALKLEYEHLSQQNSSFKDQVEQFQLQNEQSTHKQTLLENEIKELQQQQ-T 953

Query: 1369 NINEENAQLKKSSXXXXXXXXXXXXRVNDAE---AKVLELTHQLELKDSEIYQKTHEYTI 1425
            ++     Q ++              ++ +AE    +  EL  Q++ ++  I     +  +
Sbjct: 954  DLQNNIHQYEEKINLLQIEREQDQTKLMEAEEISKQKTELEKQIKHQNDAIQNLCQQVGL 1013

Query: 1426 TLTQRNDEF-ENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIER 1484
               +  +E+    + ++++ +K IE+L  + + +     +K ++       +QKE ++ER
Sbjct: 1014 LEDEHPNEYIATQKAKMIQQQKDIENL--KNDIKNLQQEIKKYQEKEALIKIQKE-KLER 1070

Query: 1485 VKLIEELNVKITESVSLNKQVAE-LNKAL--EEEVAKTNEMQTALENQEIEIVTLNDEIT 1541
             K +E+++        + +Q+ E  +KAL  +E + K  +++  L+ ++ ++V+ + +I 
Sbjct: 1071 -KYLEQISELSNHQDEMFEQIKEWRSKALMSDEYLKKIKDLEMTLKFKQDQLVSYSQKIQ 1129

Query: 1542 NLQNMVRASSSKIQK 1556
                 +     K+Q+
Sbjct: 1130 EQSVQIDQLELKVQE 1144



 Score =  112 bits (270), Expect = 7e-23
 Identities = 184/909 (20%), Positives = 384/909 (42%), Gaps = 77/909 (8%)

Query: 696  IKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDA 755
            I + +  +  ++N+++   Q+N+DL  + E+++ E        +   EQ K+Q      A
Sbjct: 23   INEFKGKEIQMLNEIEQGQQQNLDLQKENERITNEFKDRETKMLKEIEQVKLQY-----A 77

Query: 756  KIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSE 815
            ++Q+     EN E  +S++K +  +L + I   + +   L    D  G+ L + Q+   +
Sbjct: 78   ELQK-----EN-ERLISEFKDKETKLLQDIENQKQQNQQLILGKDMQGNELLQIQQ---K 128

Query: 816  YTIQEDELVNRLAVLMDHDRVVEKQLLEIE-HENKELQKKNQI---LLEENQNLQISLSD 871
              ++ D L  ++  L D  ++ ++Q  E E  +NKE+++   +   L ++N+ L     D
Sbjct: 129  LNLEIDNLKQQIQNLNDQLKLQQQQFDEKEKQKNKEIEELKLLHVQLEKQNETLTNEFKD 188

Query: 872  MQQHYNALVEKANRTDLA-ESESTKYQTQLRDLESN-LKRITHEH-QTLIVQKKKEIEDL 928
             +      +E      L  + E+ +  ++L+D E+  LK I +E  Q L +Q  KE E L
Sbjct: 189  NETKMLQEIEHQKLQQLQFQRENEQLMSELKDRENKMLKEIENEKLQNLEIQ--KENERL 246

Query: 929  EIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLEL 988
              EF  +    ++D  + N+K ++N + +   + Q  E     + LN+ ++ L K  ++ 
Sbjct: 247  RNEFKDKEIKLLQD--IENQK-QQNQQLILGKDMQGNELLQIQQKLNLEIDNL-KQQIQN 302

Query: 989  IDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYES 1048
            ++  ++ QQ Q  +  +Q   EI +L  L  Q + +   L  +  + +     M+ D + 
Sbjct: 303  LNDQLKLQQQQFDEKEKQKNKEIEELKLLHVQLELQNETLTNEFKDKET---KMILDIDH 359

Query: 1049 KLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPK 1108
               Q   K     E  Q   K  L+ +     LQ   ++ D +I +L + +      I  
Sbjct: 360  LTLQLQLKDTKGNELFQTQQKLNLELENIQLSLQQQQQQHDVKINDLVQQQDQLNKEITS 419

Query: 1109 TEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTEL 1168
             +  + S   + ++   NN D            ++++ +E  I +   LQ+  + +  + 
Sbjct: 420  YK-QLTSQKEDQINQLTNNND---------ELSVQIKGKENEINQ---LQQNLSVITNDY 466

Query: 1169 QECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTEN----DNLLSTVAELRSSI 1224
            Q+   +   L     E     + N+  I  ++ + EQL  E+    DN L+ +    S +
Sbjct: 467  QKSLKENENLTKEKLEYEAQLLENKNLIQSMQHEKEQLQNEHQLNKDNQLNDLQTQISQL 526

Query: 1225 SSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETN 1284
               V  +  +IA    Q+L Q     Q    E  VQ+       +QL   +Q + +E+ N
Sbjct: 527  QQTVTSQQSQIATDKDQNLIQ-----QNKLQEQNVQI-------QQLTVQIQ-NMEEQRN 573

Query: 1285 KIVTMEQVTSLQN-KLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXX 1343
            +     Q+   QN K++     L N Q  +   I   + +R  I+  K++          
Sbjct: 574  EFKLNNQI--FQNLKIKYVNNKLHNNQYPFKKQIKNYKSIR-PIQSSKISEIQALQSAHQ 630

Query: 1344 XXXXXXXDLRTENQSYKQMQEQSILNIN--EENAQLKKSS----XXXXXXXXXXXXRVND 1397
                    L  EN S++   +Q  + IN  +E  +++K +                ++N+
Sbjct: 631  DLNIANNKLIEENNSFQINHDQIAIEINNLQEQCRIEKETNQKISEQNQQLSSQIEQLNE 690

Query: 1398 AEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDE---FENVRQQLVEYEKRIEDLTYE 1454
               K+++   QLE+   + +    +    L Q  +E    +N  ++L    K +E+  ++
Sbjct: 691  EINKLVKERQQLEVTQKQDHNNQQDELNQLNQIQEEKVNLQNYNEKLENTNKHLEEQIFQ 750

Query: 1455 KESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEE 1514
             + +       + E      +++  +E    +L+++ N +  +   +N    E  K + E
Sbjct: 751  LQQQSQAQNTLLEEKEQLINSLKMANEQIESQLLQDQNKQQEKDECINSINLENKKLINE 810

Query: 1515 EVAKTNEMQTALENQEIEIVT-LNDEIT---NLQNMVRASSSKIQKHVSFASDTKQGRDE 1570
            +  + N  +   +  ++E    LN ++T    LQ  V   + KIQ++ +   + +Q  +E
Sbjct: 811  KELEQNSFEEHNKQDKLEFENQLNQDVTLIAQLQEEVNQQNHKIQQYENNEKNYQQQIEE 870

Query: 1571 QLDNTMNKE 1579
              ++  N E
Sbjct: 871  LKEHIQNLE 879



 Score =  109 bits (261), Expect = 8e-22
 Identities = 195/977 (19%), Positives = 418/977 (42%), Gaps = 116/977 (11%)

Query: 212  EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271
            E  K Q  + Q     + +E KD + ++LK+IE++ ++   +++ N+ L   R E   + 
Sbjct: 198  EHQKLQQLQFQRENEQLMSELKDRENKMLKEIENEKLQNLEIQKENERL---RNEFKDKE 254

Query: 272  SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEE-KGSLEIAN---------- 320
             KL Q++E                  + ++   +   EI+  K  ++  N          
Sbjct: 255  IKLLQDIENQKQQNQQLILGKDMQGNELLQIQQKLNLEIDNLKQQIQNLNDQLKLQQQQF 314

Query: 321  ---MTELTKKIELLEHLNCQIRQTNKELENKLATMGTE--------SKAVSSPSKKGSPL 369
                 +  K+IE L+ L+ Q+   N+ L N+     T+        +  +     KG+ L
Sbjct: 315  DEKEKQKNKEIEELKLLHVQLELQNETLTNEFKDKETKMILDIDHLTLQLQLKDTKGNEL 374

Query: 370  ISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVIS 429
               +   N    ++    QLS +   Q  D KIN      L      LNK++   + + S
Sbjct: 375  FQTQQKLN----LELENIQLSLQQQQQQHDVKIND-----LVQQQDQLNKEITSYKQLTS 425

Query: 430  EKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQL-KQE 488
            +K+                I   + E  Q  +  S+I     T D  +  K  E L K++
Sbjct: 426  QKEDQINQLTNNNDELSVQIKGKENEINQLQQNLSVI-----TNDYQKSLKENENLTKEK 480

Query: 489  LNDEIKDVNVKDLIEKLKSAEEQI---------TQLNDEIDAANKNMIKVKSNHKLKLKQ 539
            L  E + +  K+LI+ ++  +EQ+          QLND     ++    V S        
Sbjct: 481  LEYEAQLLENKNLIQSMQHEKEQLQNEHQLNKDNQLNDLQTQISQLQQTVTSQQSQIATD 540

Query: 540  MQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDV- 598
              + +   +K+ + N +I +LT ++ ++ ++  E +      Q   + Y + ++  +   
Sbjct: 541  KDQNLIQQNKLQEQNVQIQQLTVQIQNMEEQRNEFKLNNQIFQNLKIKYVNNKLHNNQYP 600

Query: 599  YKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADIS---QLQSDQV 655
            +KK I+         K+I  ++S K   +Q L    Q  +   +KL + +   Q+  DQ+
Sbjct: 601  FKKQIK-------NYKSIRPIQSSKISEIQALQSAHQDLNIANNKLIEENNSFQINHDQI 653

Query: 656  CSEIKSVH------------LEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDK 703
              EI ++             + EQ   LS+  ++L   I  L  +++QL  T K   N++
Sbjct: 654  AIEINNLQEQCRIEKETNQKISEQNQQLSSQIEQLNEEINKLVKERQQLEVTQKQDHNNQ 713

Query: 704  EDIMNKLQNYIQENMDLTDKLEKM--SAEKISELLAKINHEEQSKIQTQFGIDAKIQERD 761
            +D +N+L    +E ++L +  EK+  + + + E + ++  + Q++       +  I    
Sbjct: 714  QDELNQLNQIQEEKVNLQNYNEKLENTNKHLEEQIFQLQQQSQAQNTLLEEKEQLINSLK 773

Query: 762  LYIENIESELSKYKSRICRLEESIAV--MEDRRYSLERKADQLGSYLQEKQKAYSEYTIQ 819
            +  E IES+L + +++    +E I    +E+++   E++ +Q  S+ +  ++   E+  Q
Sbjct: 774  MANEQIESQLLQDQNKQQEKDECINSINLENKKLINEKELEQ-NSFEEHNKQDKLEFENQ 832

Query: 820  EDELVNRLAVLMD--------------HDRVVEKQLLEI-EH-----------EN--KEL 851
             ++ V  +A L +              +++  ++Q+ E+ EH           EN   E 
Sbjct: 833  LNQDVTLIAQLQEEVNQQNHKIQQYENNEKNYQQQIEELKEHIQNLEDFSQVSENHISEQ 892

Query: 852  QKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRIT 911
            Q+K Q L++E + L++    + Q  ++  ++  +  L   +ST  QT L +    L++  
Sbjct: 893  QEKEQQLIKELEALKLEYEHLSQQNSSFKDQVEQFQLQNEQSTHKQTLLENEIKELQQQQ 952

Query: 912  HEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEK--YEKNIEYVTQLEAQLQEYKN 969
             + Q  I Q +++I  L+IE        +  +++  +K   EK I++       L +   
Sbjct: 953  TDLQNNIHQYEEKINLLQIEREQDQTKLMEAEEISKQKTELEKQIKHQNDAIQNLCQQVG 1012

Query: 970  NIENLNMNVEELNKMNLELIDKHVQKQQTQSP-DYTEQYINEINKLNALLKQKDEEI--- 1025
             +E+ + N E +     ++I +    +  ++     +Q I +  +  AL+K + E++   
Sbjct: 1013 LLEDEHPN-EYIATQKAKMIQQQKDIENLKNDIKNLQQEIKKYQEKEALIKIQKEKLERK 1071

Query: 1026 -IALNQKINNAQVSYMSMVSDYESKLA---QFTTKLENMEEEMQRVSKQLLDSKQHNEEL 1081
             +    +++N Q      + ++ SK     ++  K++++E  ++    QL+   Q  +E 
Sbjct: 1072 YLEQISELSNHQDEMFEQIKEWRSKALMSDEYLKKIKDLEMTLKFKQDQLVSYSQKIQEQ 1131

Query: 1082 QILVREQDDQIKELKET 1098
             + + + + +++ELK+T
Sbjct: 1132 SVQIDQLELKVQELKQT 1148



 Score = 84.6 bits (200), Expect = 2e-14
 Identities = 141/733 (19%), Positives = 304/733 (41%), Gaps = 51/733 (6%)

Query: 858  LLEENQNLQISLSDMQQHYNALVEKANRTDLAE-SESTKYQTQLRDLESNLKRITHEHQT 916
            +L+E ++ ++     Q+     + +    ++   +E  + Q Q  DL+   +RIT+E + 
Sbjct: 1    MLKEIEHEKLQYIQQQKENEKFINEFKGKEIQMLNEIEQGQQQNLDLQKENERITNEFKD 60

Query: 917  LIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNM 976
               +  KEIE +++++    E    ++++++E  +K  + +  +E Q Q+ +  I   +M
Sbjct: 61   RETKMLKEIEQVKLQY---AELQKENERLISEFKDKETKLLQDIENQKQQNQQLILGKDM 117

Query: 977  NVEEL----NKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKI 1032
               EL     K+NLE ID    KQQ Q+       +N+  KL    +Q DE+    N++I
Sbjct: 118  QGNELLQIQQKLNLE-IDN--LKQQIQN-------LNDQLKLQQ--QQFDEKEKQKNKEI 165

Query: 1033 NNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQ- 1091
               ++ ++ +    E+   +F      M +E++    Q L  ++ NE+L   +++++++ 
Sbjct: 166  EELKLLHVQLEKQNETLTNEFKDNETKMLQEIEHQKLQQLQFQRENEQLMSELKDRENKM 225

Query: 1092 IKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFI 1151
            +KE++  KL   + I K    + +   +       +++             K  +  E +
Sbjct: 226  LKEIENEKLQ-NLEIQKENERLRNEFKDKEIKLLQDIENQKQQNQQLILG-KDMQGNELL 283

Query: 1152 QERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTEND 1211
            Q +  L  +   L  ++Q       QL+    +    +    ++I +LK    QL  +N+
Sbjct: 284  QIQQKLNLEIDNLKQQIQNLND---QLKLQQQQFDEKEKQKNKEIEELKLLHVQLELQNE 340

Query: 1212 NLLSTVAELRSSISSAVDQ--RGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYE 1269
             L +   +  + +   +D      ++ +     L Q +         +++ L   + +++
Sbjct: 341  TLTNEFKDKETKMILDIDHLTLQLQLKDTKGNELFQTQQKLNLELENIQLSLQQQQQQHD 400

Query: 1270 -QLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIE 1328
             ++ D VQ   Q++ NK     ++TS +     KE+ +  L     ++  QI+   +EI 
Sbjct: 401  VKINDLVQQ--QDQLNK-----EITSYKQLTSQKEDQINQLTNNNDELSVQIKGKENEI- 452

Query: 1329 DEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXX 1388
            ++                    +L  E   Y   + Q + N N   +   +         
Sbjct: 453  NQLQQNLSVITNDYQKSLKENENLTKEKLEY---EAQLLENKNLIQSMQHEKEQLQNEHQ 509

Query: 1389 XXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRI 1448
                 ++ND + ++ +L   +  + S+I     +  I   +  ++   ++Q  V+ +   
Sbjct: 510  LNKDNQLNDLQTQISQLQQTVTSQQSQIATDKDQNLIQQNKLQEQNVQIQQLTVQIQNME 569

Query: 1449 EDLTYEKESELAI--LRLKMHENANHYETMQKESEIERVKLIEEL-NVKITESVSLNKQV 1505
            E     K +      L++K   N  H      + +I+  K I  + + KI+E  +L    
Sbjct: 570  EQRNEFKLNNQIFQNLKIKYVNNKLHNNQYPFKKQIKNYKSIRPIQSSKISEIQALQSAH 629

Query: 1506 AELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTK 1565
             +LN A  + + + N  Q  + + +I I     EI NLQ   R      QK +S  +   
Sbjct: 630  QDLNIANNKLIEENNSFQ--INHDQIAI-----EINNLQEQCRIEKETNQK-ISEQNQQL 681

Query: 1566 QGRDEQLDNTMNK 1578
              + EQL+  +NK
Sbjct: 682  SSQIEQLNEEINK 694


>UniRef50_Q6BUQ9 Cluster: Similar to sp|P25386 Saccharomyces
            cerevisiae YDL058w USO1; n=1; Debaryomyces hansenii|Rep:
            Similar to sp|P25386 Saccharomyces cerevisiae YDL058w
            USO1 - Debaryomyces hansenii (Yeast) (Torulaspora
            hansenii)
          Length = 2042

 Score =  145 bits (352), Expect = 8e-33
 Identities = 239/1163 (20%), Positives = 498/1163 (42%), Gaps = 82/1163 (7%)

Query: 483  EQLKQELNDEIKDVNVK--DLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQM 540
            EQ +Q+  D I  ++ +   L ++ K ++  I     ++D+    +  +    + +++++
Sbjct: 869  EQARQKAEDGINKMSRELFHLSKQKKESDSNIKSHEKKVDSLKLEIANITKTFEARIEKL 928

Query: 541  QKTIDNFS-KVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQL---HLVDY--DSGRMI 594
            QK  D F  KV D NK+I        H  +K  E++E+  +++    HL+D    +    
Sbjct: 929  QKANDLFKEKVEDLNKKISESVSYNEHSDKKSREMKEKLDDVEATNEHLMDKLRSAASAF 988

Query: 595  ESDVYKKMIEMENLAETRLKAISLLESQKFDLVQ-ELHILQQKYDEVEDKLADISQLQSD 653
            +   Y K    + + + +++  S  ++ +F+ +Q E  +L+++ +++ ++        S 
Sbjct: 989  QEMKYAKTSSDKEIEKYKIEIKS--KNDEFNSLQLEFTLLKEEKEKINEEFESFKVKSSA 1046

Query: 654  QVCSEIKSVH-LEEQIDALSASKKELALVIENLK--LDKE-QLYGTIKDLENDK--EDIM 707
            +V     S++ L+   D+L ++   ++   E LK  L +E + Y  +K +E DK  E + 
Sbjct: 1047 EVGKLNSSINDLKSAKDSLDSNHSTISNEFEELKEKLSQESKRYSNLK-IEYDKLLESLK 1105

Query: 708  NKLQNYIQENMDLTDKLEKMSAEKISELLAKINHE-EQSKIQTQF--GIDAKIQERDLYI 764
             + +   ++  D+ +  E   A++ S     +N + + SK++ +    +DAK  E +  I
Sbjct: 1106 CENEKLKKDLEDIDNSKENAEAKQKSVEEELLNFKTKHSKVREELEKSLDAKTGEYNDAI 1165

Query: 765  ENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELV 824
            E ++++     S      + ++ ++     L +  +   S   E +K   E+      L 
Sbjct: 1166 EKLKNKDISIASLKETHSKKVSELDSGHSKLSQDLEAANSRCLETEKQIKEHLESSSNLA 1225

Query: 825  NRLAVLMDHDRVVEKQLLEIEHE-NKELQKKNQILLEENQNLQISLSDMQQHYNALVEKA 883
            ++++ L      +E  +   E E NK  ++  +   E NQNL    ++ Q+      EK 
Sbjct: 1226 DQISALEKVKGELEASINNAEQESNKSREEFEKEKAELNQNLTNLEAEKQK-----AEK- 1279

Query: 884  NRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDK 943
             R DL + E    + +L  L+  L     + +T + + K +I   + E     E      
Sbjct: 1280 -RLDLVQEEKAIAEKELAKLKQILDD-NSKLETEVSELKSDITKFKDEHTIINEKLSIKT 1337

Query: 944  KVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELN--KMNLELIDKHVQKQQTQSP 1001
            K L+EK ++    +   E++L++   +++N  + V++L   K +LE   K ++     + 
Sbjct: 1338 KELSEKKDQ----IENQESKLKDLAKSLDNEKILVKDLKEKKESLETRIKELENDIAYAS 1393

Query: 1002 DYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENME 1061
            + +++   +   L   LK  ++++  LN K  N       ++SD+E  ++     L+   
Sbjct: 1394 NSSKEMQTKNENLETKLKSTEKDLSTLNSKFTNETKILKDLISDHEVSISSLKVDLDKKV 1453

Query: 1062 EEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKET----KLTFE--MNIPKTEGMIIS 1115
            +E+++    L      +E  + +++E  D+IKEL++     K   E  +N    E  +  
Sbjct: 1454 QEVEKERNML------SENSETVIKEYGDKIKELEKALGIAKTAHESKLNAMSKEKKLAD 1507

Query: 1116 STIEPMSDD----ANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQEC 1171
             +++ ++++     N+ +            L V+ E E     S L E+ A+L  E +  
Sbjct: 1508 ESLKYINNEFEIHKNDSNESTTKLTKEIESLNVKLENERKLSTSKLSEREAELKKESETL 1567

Query: 1172 YTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRS--SISSAVD 1229
                 QLE    +L     V  +   QLK+ LE    E D L S V E++S  +++ +  
Sbjct: 1568 KATGKQLEDEIEKLKKEKDVVSDNF-QLKN-LEFSTLEKD-LASKVEEIKSINNVTESYK 1624

Query: 1230 QRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEE-TNKIVT 1288
            +   +I    KQ     EA  QK   + + +L     K E+L  SV S+T+E  TNK+  
Sbjct: 1625 KESDDIKSKTKQLENDLEAA-QKFGDKTKEELDTLNQKIEEL-KSVNSNTEETWTNKLKE 1682

Query: 1289 ME--------QVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXX 1340
             E        Q  S+  +L   +   +   E    + N+++ L+ +IE EK         
Sbjct: 1683 SESSYAALDEQKKSISQELSALKSSDKAASEMTKQLENELQTLKDDIE-EKSRSKKELEE 1741

Query: 1341 XXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEA 1400
                      +L  +  + K+  +     I + +A+LK+ S            +    + 
Sbjct: 1742 KSTTLSSTINELENKLDAMKKELDSEKSVIEKLSAELKEHSKLSADL------KEYKEKF 1795

Query: 1401 KVLELTHQLELKDSEIYQKTH-EYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESEL 1459
            + LE  H+   K  +     H E    L  + D  ++     ++ + +IE L  E  S  
Sbjct: 1796 EQLEKEHEQLKKKFDAEGNIHGEKMKELKSKLDSLQDDLTAAMDLKSKIESLNQELLSTK 1855

Query: 1460 AILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKT 1519
                 ++ +     E+ Q     E+ +L ++LN    E++S  K+  +LN   E E    
Sbjct: 1856 TTKDDEIKKLTKDLESTQALKNNEK-ELKKDLNSS-KENISTLKE--DLNALKENETRLK 1911

Query: 1520 NEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDE--QLDNTMN 1577
             +++ +  N++     L    ++ +N  + +     +  +F    K+ ++E   L   + 
Sbjct: 1912 QDLEISKANEDSLNKELESLKSSQKNKEKDNIDFDSQKANFLESEKKLKEEVEALKKKLK 1971

Query: 1578 KELLDAVPRAELDLAMYMLHQRD 1600
            ++    VPR+ELD  M ++   D
Sbjct: 1972 EQSSTMVPRSELDDLMLLMSDID 1994



 Score =  138 bits (333), Expect = 2e-30
 Identities = 198/876 (22%), Positives = 396/876 (45%), Gaps = 85/876 (9%)

Query: 479  AKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLK 538
            +KV+E+L++ L+ +  + N  D IEKLK+ +  I  L +     +K + ++ S H  KL 
Sbjct: 1144 SKVREELEKSLDAKTGEYN--DAIEKLKNKDISIASLKE---THSKKVSELDSGHS-KLS 1197

Query: 539  QMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDV 598
            Q  +  +  S+  ++ K+I    E   +L+ +++ LE+ KG L+  + + +       + 
Sbjct: 1198 QDLEAAN--SRCLETEKQIKEHLESSSNLADQISALEKVKGELEASINNAEQESNKSREE 1255

Query: 599  YKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQK-YDEVEDKLADISQLQSDQVCS 657
            ++K     N   T L+A      ++ DLVQE   + +K   +++  L D S+L+++   S
Sbjct: 1256 FEKEKAELNQNLTNLEAEKQKAEKRLDLVQEEKAIAEKELAKLKQILDDNSKLETE--VS 1313

Query: 658  EIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQEN 717
            E+KS  + +  D  +   ++L++  + L   K+Q    I++ E+  +D+   L N     
Sbjct: 1314 ELKS-DITKFKDEHTIINEKLSIKTKELSEKKDQ----IENQESKLKDLAKSLDNEKILV 1368

Query: 718  MDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSR 777
             DL +K E +   +I EL   I +   S  + Q     K +  +  +++ E +LS   S+
Sbjct: 1369 KDLKEKKESLET-RIKELENDIAYASNSSKEMQ----TKNENLETKLKSTEKDLSTLNSK 1423

Query: 778  ICRLEESIA-VMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRV 836
                 + +  ++ D   S+      L   +QE +K  +  +   + ++       D  + 
Sbjct: 1424 FTNETKILKDLISDHEVSISSLKVDLDKKVQEVEKERNMLSENSETVIKEYG---DKIKE 1480

Query: 837  VEKQL--LEIEHENK-ELQKKNQILLEE-----NQNLQISLSDMQQHYNALVEKANRTDL 888
            +EK L   +  HE+K     K + L +E     N   +I  +D  +    L ++    ++
Sbjct: 1481 LEKALGIAKTAHESKLNAMSKEKKLADESLKYINNEFEIHKNDSNESTTKLTKEIESLNV 1540

Query: 889  AESESTKYQT-QLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLN 947
                  K  T +L + E+ LK+   E +TL    K ++ED       +IE   ++K V++
Sbjct: 1541 KLENERKLSTSKLSEREAELKK---ESETLKATGK-QLED-------EIEKLKKEKDVVS 1589

Query: 948  EKYE-KNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQ 1006
            + ++ KN+E+ T LE  L      I+++N NV E  K           K+       T+Q
Sbjct: 1590 DNFQLKNLEFST-LEKDLASKVEEIKSIN-NVTESYK-----------KESDDIKSKTKQ 1636

Query: 1007 YINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQR 1066
              N++        +  EE+  LNQKI   +    +    + +KL +  +    ++E+ + 
Sbjct: 1637 LENDLEAAQKFGDKTKEELDTLNQKIEELKSVNSNTEETWTNKLKESESSYAALDEQKKS 1696

Query: 1067 VSKQLLDSKQHNEELQILVREQDDQIKELK---ETKLTFEMNIPKTEGMIISSTIEPMSD 1123
            +S++L   K  ++    + ++ +++++ LK   E K   +  + + +   +SSTI  +  
Sbjct: 1697 ISQELSALKSSDKAASEMTKQLENELQTLKDDIEEKSRSKKEL-EEKSTTLSSTINELE- 1754

Query: 1124 DANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQL----E 1179
              N +D             ++  E+  I++ S   ++ +KL+ +L+E   K  QL    E
Sbjct: 1755 --NKLDAMKK---------ELDSEKSVIEKLSAELKEHSKLSADLKEYKEKFEQLEKEHE 1803

Query: 1180 TLNTELTGHDVVNQEQINQLKSKLEQLN---TENDNLLSTVAELRSSISSAVDQRGFEIA 1236
             L  +      ++ E++ +LKSKL+ L    T   +L S +  L   + S    +  EI 
Sbjct: 1804 QLKKKFDAEGNIHGEKMKELKSKLDSLQDDLTAAMDLKSKIESLNQELLSTKTTKDDEIK 1863

Query: 1237 ELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQ 1296
            +L K  L   +A  +  E EL+  L++ +     L + + +  + ET     +E   + +
Sbjct: 1864 KLTKD-LESTQA-LKNNEKELKKDLNSSKENISTLKEDLNALKENETRLKQDLEISKANE 1921

Query: 1297 NKLQDKEEHLRNLQE-KYADVINQIEILRSEIEDEK 1331
            + L  + E L++ Q+ K  D I+      + +E EK
Sbjct: 1922 DSLNKELESLKSSQKNKEKDNIDFDSQKANFLESEK 1957



 Score =  128 bits (309), Expect = 1e-27
 Identities = 224/1028 (21%), Positives = 448/1028 (43%), Gaps = 101/1028 (9%)

Query: 151  IKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATT-----------XXXXX 199
            IK K++  + LQ++  +++    + +EKINE+ +  + K+ A                  
Sbjct: 1009 IKSKNDEFNSLQLEFTLLK----EEKEKINEEFESFKVKSSAEVGKLNSSINDLKSAKDS 1064

Query: 200  XXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEW-------KDEKQRLLKDIESKDVRISS 252
                        E+ K+++++  + +  ++ E+       K E ++L KD+E  D    +
Sbjct: 1065 LDSNHSTISNEFEELKEKLSQESKRYSNLKIEYDKLLESLKCENEKLKKDLEDIDNSKEN 1124

Query: 253  LEEANKLLEAARFEISLEHSKLAQELEQX-XXXXXXXXXXXXXLAKQSIEPSCEEKTEIE 311
             E   K +E        +HSK+ +ELE+               L  + I  +  ++T  +
Sbjct: 1125 AEAKQKSVEEELLNFKTKHSKVREELEKSLDAKTGEYNDAIEKLKNKDISIASLKETHSK 1184

Query: 312  EKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSK-KGSPLI 370
            +   L+  +    +K  + LE  N +  +T K+++  L +    +  +S+  K KG    
Sbjct: 1185 KVSELDSGH----SKLSQDLEAANSRCLETEKQIKEHLESSSNLADQISALEKVKGELEA 1240

Query: 371  SRKSGRNTASKMKSPWSQLSSETLNQD-TDKKINKNEIAKLEMVIQSLNKDLVDKEYVIS 429
            S  +    ++K +  + +  +E LNQ+ T+ +  K +  K          DLV +E  I+
Sbjct: 1241 SINNAEQESNKSREEFEKEKAE-LNQNLTNLEAEKQKAEK--------RLDLVQEEKAIA 1291

Query: 430  EKDTXXXXXXXXXXGK-DTLIAQLQLEHQQHMEGPSLIH--VGTNTEDVNEIAKVQEQLK 486
            EK+            K +T +++L+ +  +  +  ++I+  +   T++++E     E  +
Sbjct: 1292 EKELAKLKQILDDNSKLETEVSELKSDITKFKDEHTIINEKLSIKTKELSEKKDQIENQE 1351

Query: 487  QELNDEIKDVN-----VKDLIEKLKSAEEQITQLNDEIDAA---NKNMIKVKSNHKLKLK 538
             +L D  K ++     VKDL EK +S E +I +L ++I  A   +K M     N + KLK
Sbjct: 1352 SKLKDLAKSLDNEKILVKDLKEKKESLETRIKELENDIAYASNSSKEMQTKNENLETKLK 1411

Query: 539  QMQKTIDNF-SKVSDSNKEI--------VRLTEELHHLSQKVAELEEEKGNLQLHLVDYD 589
              +K +    SK ++  K +        V ++     L +KV E+E+E+     +++  +
Sbjct: 1412 STEKDLSTLNSKFTNETKILKDLISDHEVSISSLKVDLDKKVQEVEKER-----NMLSEN 1466

Query: 590  SGRMIE--SDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADI 647
            S  +I+   D  K++ +   +A+T  ++     S++  L  E   L+   +E E    D 
Sbjct: 1467 SETVIKEYGDKIKELEKALGIAKTAHESKLNAMSKEKKLADE--SLKYINNEFEIHKND- 1523

Query: 648  SQLQSDQVCSEIKSVHLE-EQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDI 706
            S   + ++  EI+S++++ E    LS SK  L+     LK + E L  T K LE++ E  
Sbjct: 1524 SNESTTKLTKEIESLNVKLENERKLSTSK--LSEREAELKKESETLKATGKQLEDEIEK- 1580

Query: 707  MNKLQNYIQENMDLTD----KLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDL 762
            + K ++ + +N  L +     LEK  A K+ E +  IN+  +S  +    I +K ++ + 
Sbjct: 1581 LKKEKDVVSDNFQLKNLEFSTLEKDLASKVEE-IKSINNVTESYKKESDDIKSKTKQLEN 1639

Query: 763  YIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDE 822
             +E  +    K K  +  L + I  ++    + E   +   + L+E + +Y+    Q+  
Sbjct: 1640 DLEAAQKFGDKTKEELDTLNQKIEELKSVNSNTE---ETWTNKLKESESSYAALDEQKKS 1696

Query: 823  LVNRLAVLMDHDRVVEKQLLEIEHE----NKELQKKNQILLEENQNLQISLSDMQQHYNA 878
            +   L+ L   D+   +   ++E+E      ++++K++   E  +      S + +  N 
Sbjct: 1697 ISQELSALKSSDKAASEMTKQLENELQTLKDDIEEKSRSKKELEEKSTTLSSTINELENK 1756

Query: 879  LVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIES 938
            L       D  +S   K   +L++  S L     E++    Q +KE E L+ +F+   E 
Sbjct: 1757 LDAMKKELDSEKSVIEKLSAELKE-HSKLSADLKEYKEKFEQLEKEHEQLKKKFDA--EG 1813

Query: 939  AIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQT 998
             I  +K + E   K       L A + + K+ IE+LN   +EL  ++ +       K+ T
Sbjct: 1814 NIHGEK-MKELKSKLDSLQDDLTAAM-DLKSKIESLN---QEL--LSTKTTKDDEIKKLT 1866

Query: 999  QSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLA---QFTT 1055
            +  + T+   N   +L   L    E I  L + +N  + +   +  D E   A       
Sbjct: 1867 KDLESTQALKNNEKELKKDLNSSKENISTLKEDLNALKENETRLKQDLEISKANEDSLNK 1926

Query: 1056 KLENMEEEMQRVSKQLL--DSKQHN--EELQILVREQDDQIKELKETKLTFEMNIPKTEG 1111
            +LE+++   +   K  +  DS++ N  E  + L  E +   K+LKE   T        + 
Sbjct: 1927 ELESLKSSQKNKEKDNIDFDSQKANFLESEKKLKEEVEALKKKLKEQSSTMVPRSELDDL 1986

Query: 1112 MIISSTIE 1119
            M++ S I+
Sbjct: 1987 MLLMSDID 1994



 Score =  124 bits (298), Expect = 3e-26
 Identities = 222/1167 (19%), Positives = 500/1167 (42%), Gaps = 103/1167 (8%)

Query: 484  QLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKT 543
            +L +EL+ +   +  +   EK+K++E ++ +L++EI+  N++   VK        ++++ 
Sbjct: 747  ELYEELDTKHSLLKTQLEEEKVKASEMEM-KLHEEINKLNRDCEDVKVQLDKACNELKEL 805

Query: 544  IDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMI 603
             +  S VS+        T+ L    +   E E   G     L +      +  D+ K + 
Sbjct: 806  KNKHSSVSEKYSNT---TKSLQATEKSKKEFETSSGKYFKELQEALKKFGVSDDLVKSLE 862

Query: 604  E-MENLAETRLKA----------ISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQS 652
            + +EN  + R KA          +  L  QK +    +   ++K D ++ ++A+I++   
Sbjct: 863  QKLENSEQARQKAEDGINKMSRELFHLSKQKKESDSNIKSHEKKVDSLKLEIANITKTFE 922

Query: 653  DQVCSEIKSVHL-EEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQ 711
             ++    K+  L +E+++ L+    E     E+      ++   + D+E   E +M+KL+
Sbjct: 923  ARIEKLQKANDLFKEKVEDLNKKISESVSYNEHSDKKSREMKEKLDDVEATNEHLMDKLR 982

Query: 712  NYIQENMDLTDKLEKMSAEKISE---LLAKINHEEQSKIQTQFGI----DAKIQER-DLY 763
            +      ++  K  K S++K  E   +  K  ++E + +Q +F +      KI E  + +
Sbjct: 983  SAASAFQEM--KYAKTSSDKEIEKYKIEIKSKNDEFNSLQLEFTLLKEEKEKINEEFESF 1040

Query: 764  IENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDEL 823
                 +E+ K  S I  L+ +   ++    ++  + ++L   L ++ K YS   I+ D+L
Sbjct: 1041 KVKSSAEVGKLNSSINDLKSAKDSLDSNHSTISNEFEELKEKLSQESKRYSNLKIEYDKL 1100

Query: 824  VNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEE-----------NQNLQISLSDM 872
            +  L      +  ++K L +I++  +  + K + + EE            + L+ SL   
Sbjct: 1101 LESLKC---ENEKLKKDLEDIDNSKENAEAKQKSVEEELLNFKTKHSKVREELEKSLDAK 1157

Query: 873  QQHYNALVEKANRTDLA-ESESTKYQTQLRDLESNLKRITHEHQ---TLIVQKKKEI-ED 927
               YN  +EK    D++  S    +  ++ +L+S   +++ + +   +  ++ +K+I E 
Sbjct: 1158 TGEYNDAIEKLKNKDISIASLKETHSKKVSELDSGHSKLSQDLEAANSRCLETEKQIKEH 1217

Query: 928  LEIEFNTQIE-SAIRDKK-----VLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEEL 981
            LE   N   + SA+   K      +N   +++ +   + E +  E   N+ NL    ++ 
Sbjct: 1218 LESSSNLADQISALEKVKGELEASINNAEQESNKSREEFEKEKAELNQNLTNLEAEKQKA 1277

Query: 982  NK-MNLELIDKHVQKQQ----TQSPDYTEQYINEINKLNA-LLKQKDEEIIALNQK--IN 1033
             K ++L   +K + +++     Q  D   +   E+++L + + K KDE  I +N+K  I 
Sbjct: 1278 EKRLDLVQEEKAIAEKELAKLKQILDDNSKLETEVSELKSDITKFKDEHTI-INEKLSIK 1336

Query: 1034 NAQVS-YMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQI 1092
              ++S     + + ESKL      L+N +  ++ + ++    +   +EL+  +    +  
Sbjct: 1337 TKELSEKKDQIENQESKLKDLAKSLDNEKILVKDLKEKKESLETRIKELENDIAYASNSS 1396

Query: 1093 KELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKV---QEEEE 1149
            KE++      E  +  TE   +S+     +++   +             LKV   ++ +E
Sbjct: 1397 KEMQTKNENLETKLKSTE-KDLSTLNSKFTNETKILKDLISDHEVSISSLKVDLDKKVQE 1455

Query: 1150 FIQERSVLQEQSAKLNTELQECYTKIIQLE-TLNTELTGHDVVNQEQINQLK---SKLEQ 1205
              +ER++L E S    T ++E   KI +LE  L    T H+        + K     L+ 
Sbjct: 1456 VEKERNMLSENS---ETVIKEYGDKIKELEKALGIAKTAHESKLNAMSKEKKLADESLKY 1512

Query: 1206 LNTENDNLLSTVAELRSSISSAVDQRGFEI---AELWKQHLAQREADFQKTEHELRVQLS 1262
            +N E +   +   E  + ++  ++    ++    +L    L++REA+ +K    L+    
Sbjct: 1513 INNEFEIHKNDSNESTTKLTKEIESLNVKLENERKLSTSKLSEREAELKKESETLKATGK 1572

Query: 1263 AFESKYEQL---LDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQ 1319
              E + E+L    D V  + Q +  +  T+E+   L +K+++ +  + N+ E Y    + 
Sbjct: 1573 QLEDEIEKLKKEKDVVSDNFQLKNLEFSTLEK--DLASKVEEIKS-INNVTESYKKESDD 1629

Query: 1320 IEILRSEIEDEKVA---FXXXXXXXXXXXXXXXXDLRTENQSYKQM-------QEQSILN 1369
            I+    ++E++  A   F                +L++ N + ++         E S   
Sbjct: 1630 IKSKTKQLENDLEAAQKFGDKTKEELDTLNQKIEELKSVNSNTEETWTNKLKESESSYAA 1689

Query: 1370 INEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKD---SEIYQKTHEYTIT 1426
            ++E+   + +                   E ++  L   +E K     E+ +K+   + T
Sbjct: 1690 LDEQKKSISQELSALKSSDKAASEMTKQLENELQTLKDDIEEKSRSKKELEEKSTTLSST 1749

Query: 1427 LTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVK 1486
            + +  ++ + ++++L   +  IE L+ E + E + L   + E    +E ++KE E  + K
Sbjct: 1750 INELENKLDAMKKELDSEKSVIEKLSAELK-EHSKLSADLKEYKEKFEQLEKEHEQLKKK 1808

Query: 1487 LIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALE--NQEI--EIVTLNDEITN 1542
               E N+   +   L  ++     +L++++    ++++ +E  NQE+     T +DEI  
Sbjct: 1809 FDAEGNIHGEKMKELKSKL----DSLQDDLTAAMDLKSKIESLNQELLSTKTTKDDEIKK 1864

Query: 1543 LQNMVRASSSKIQKHVSFASDTKQGRD 1569
            L   + ++ +          D    ++
Sbjct: 1865 LTKDLESTQALKNNEKELKKDLNSSKE 1891



 Score =  105 bits (253), Expect = 8e-21
 Identities = 146/754 (19%), Positives = 326/754 (43%), Gaps = 73/754 (9%)

Query: 826  RLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANR 885
            RL   + HD   E Q        +EL  K+ +L  + +  ++  S+M+   +  + K NR
Sbjct: 727  RLKRALFHDPHAEPQGHISFELYEELDTKHSLLKTQLEEEKVKASEMEMKLHEEINKLNR 786

Query: 886  T-DLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKK 944
              +  + +  K   +L++L++    ++ ++     +  +  E  + EF T      ++ +
Sbjct: 787  DCEDVKVQLDKACNELKELKNKHSSVSEKYSNT-TKSLQATEKSKKEFETSSGKYFKELQ 845

Query: 945  VLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEE-LNKMNLELIDKHVQKQQTQSPDY 1003
               +K+  + + V  LE +L+    N E      E+ +NKM+ EL   H+ KQ+ +S   
Sbjct: 846  EALKKFGVSDDLVKSLEQKLE----NSEQARQKAEDGINKMSRELF--HLSKQKKESDSN 899

Query: 1004 TEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEE 1063
             + +  +++ L   +    +   A  +K+  A   +   V D   K+++  +  E+ +++
Sbjct: 900  IKSHEKKVDSLKLEIANITKTFEARIEKLQKANDLFKEKVEDLNKKISESVSYNEHSDKK 959

Query: 1064 MQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSD 1123
             + + ++L D +  NE L   +R      +E+K  K + +  I K         I+  +D
Sbjct: 960  SREMKEKLDDVEATNEHLMDKLRSAASAFQEMKYAKTSSDKEIEK-----YKIEIKSKND 1014

Query: 1124 DANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNT 1183
            + N++               ++EE+E I E    +    K + E+ +  + I  L++   
Sbjct: 1015 EFNSLQLEFTL---------LKEEKEKINEE--FESFKVKSSAEVGKLNSSINDLKSAKD 1063

Query: 1184 ELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHL 1243
             L  +      +  +LK KL Q +    NL     +L  S+    ++   ++ ++     
Sbjct: 1064 SLDSNHSTISNEFEELKEKLSQESKRYSNLKIEYDKLLESLKCENEKLKKDLEDI-DNSK 1122

Query: 1244 AQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKE 1303
               EA  +  E E    L  F++K+ ++ + ++ S   +T       +      KL++K+
Sbjct: 1123 ENAEAKQKSVEEE----LLNFKTKHSKVREELEKSLDAKTG------EYNDAIEKLKNKD 1172

Query: 1304 EHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQ 1363
              + +L+E ++  +++++   S++  +  A                  L TE Q  + ++
Sbjct: 1173 ISIASLKETHSKKVSELDSGHSKLSQDLEA-------------ANSRCLETEKQIKEHLE 1219

Query: 1364 EQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEY 1423
              S  N+ ++ + L+K               +N+AE +  +   + E + +E+ Q     
Sbjct: 1220 SSS--NLADQISALEKVKGELEAS-------INNAEQESNKSREEFEKEKAELNQ----- 1265

Query: 1424 TITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIE 1483
             +T  +   +    R  LV+ EK I       E ELA L+  + +N+   ET   E + +
Sbjct: 1266 NLTNLEAEKQKAEKRLDLVQEEKAI------AEKELAKLKQILDDNSK-LETEVSELKSD 1318

Query: 1484 RVKLIEELNVKITESVSL-NKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITN 1542
              K  +E  + I E +S+  K+++E    +E + +K  ++  +L+N++I +  L ++  +
Sbjct: 1319 ITKFKDEHTI-INEKLSIKTKELSEKKDQIENQESKLKDLAKSLDNEKILVKDLKEKKES 1377

Query: 1543 LQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTM 1576
            L+  ++   + I  + S +S   Q ++E L+  +
Sbjct: 1378 LETRIKELENDI-AYASNSSKEMQTKNENLETKL 1410



 Score = 83.8 bits (198), Expect = 4e-14
 Identities = 168/898 (18%), Positives = 376/898 (41%), Gaps = 98/898 (10%)

Query: 714  IQENMDLTDKLEKMSAE----KISELLAKINHEEQSKIQTQFGIDAKIQ--ERDLYIENI 767
            + E +D    L K   E    K SE+  K+ HEE +K+      D K+Q  +    ++ +
Sbjct: 748  LYEELDTKHSLLKTQLEEEKVKASEMEMKL-HEEINKLNRDCE-DVKVQLDKACNELKEL 805

Query: 768  ESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRL 827
            +++ S    +     +S+   E  +   E  +   G Y +E Q+A  ++ + +D LV  L
Sbjct: 806  KNKHSSVSEKYSNTTKSLQATEKSKKEFETSS---GKYFKELQEALKKFGVSDD-LVKSL 861

Query: 828  AVLMDHDRV--------VEKQLLEIEHENKELQKKNQILLEENQ---NLQISLSDMQQHY 876
               +++           + K   E+ H +K+ ++ +  +    +   +L++ ++++ + +
Sbjct: 862  EQKLENSEQARQKAEDGINKMSRELFHLSKQKKESDSNIKSHEKKVDSLKLEIANITKTF 921

Query: 877  NALVEKANRTDLAESESTKYQTQLRDLESNLKRIT--HEHQTLIVQKKKE-IEDLEIEFN 933
             A +EK  + +        ++ ++ DL   +      +EH     ++ KE ++D+E    
Sbjct: 922  EARIEKLQKAN------DLFKEKVEDLNKKISESVSYNEHSDKKSREMKEKLDDVEATNE 975

Query: 934  TQIESAIRDKKVLNE-KYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLE--LID 990
              ++          E KY K     T  + ++++YK  I++ N   +E N + LE  L+ 
Sbjct: 976  HLMDKLRSAASAFQEMKYAK-----TSSDKEIEKYKIEIKSKN---DEFNSLQLEFTLLK 1027

Query: 991  KHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKL 1050
            +  +K   +   +  +   E+ KLN+ +        +L+   N++ +S  +   + + KL
Sbjct: 1028 EEKEKINEEFESFKVKSSAEVGKLNSSINDLKSAKDSLDS--NHSTIS--NEFEELKEKL 1083

Query: 1051 AQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIK--ELKETKLTFEMNIPK 1108
            +Q + +  N++ E  ++ + L   K  NE+L+  + + D+  +  E K+  +  E+   K
Sbjct: 1084 SQESKRYSNLKIEYDKLLESL---KCENEKLKKDLEDIDNSKENAEAKQKSVEEELLNFK 1140

Query: 1109 TEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTEL 1168
            T+   +   +E       ++D            LK ++    I   S+ +  S K++ EL
Sbjct: 1141 TKHSKVREELE------KSLDAKTGEYNDAIEKLKNKD----ISIASLKETHSKKVS-EL 1189

Query: 1169 QECYTKIIQ-LETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSA 1227
               ++K+ Q LE  N+          E   Q+K  LE  +   D + S + +++  + ++
Sbjct: 1190 DSGHSKLSQDLEAANSRCL-------ETEKQIKEHLESSSNLADQI-SALEKVKGELEAS 1241

Query: 1228 VDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFES---KYEQLLDSVQSSTQEETN 1284
            ++          +Q   +   +F+K + EL   L+  E+   K E+ LD VQ        
Sbjct: 1242 INNA--------EQESNKSREEFEKEKAELNQNLTNLEAEKQKAEKRLDLVQEEKAIAEK 1293

Query: 1285 KIVTMEQVTSLQNKLQDKEEHLRNLQEKYAD---VINQ-IEILRSEIEDEKVAFXXXXXX 1340
            ++  ++Q+    +KL+ +   L++   K+ D   +IN+ + I   E+ ++K         
Sbjct: 1294 ELAKLKQILDDNSKLETEVSELKSDITKFKDEHTIINEKLSIKTKELSEKK----DQIEN 1349

Query: 1341 XXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEA 1400
                       L  E    K ++E+   ++     +L+               +  + E 
Sbjct: 1350 QESKLKDLAKSLDNEKILVKDLKEKKE-SLETRIKELENDIAYASNSSKEMQTKNENLET 1408

Query: 1401 KVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELA 1460
            K+      L   +S+    T+E  I     +D   ++    V+ +K+++++  E+     
Sbjct: 1409 KLKSTEKDLSTLNSKF---TNETKILKDLISDHEVSISSLKVDLDKKVQEVEKERNMLSE 1465

Query: 1461 ILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTN 1520
                 + E  +  + ++K   I +     +LN    E    ++ +  +N   E     +N
Sbjct: 1466 NSETVIKEYGDKIKELEKALGIAKTAHESKLNAMSKEKKLADESLKYINNEFEIHKNDSN 1525

Query: 1521 EMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNK 1578
            E  T L     EI +LN ++ N + +  +  S+ +  +   S+T +   +QL++ + K
Sbjct: 1526 ESTTKLTK---EIESLNVKLENERKLSTSKLSEREAELKKESETLKATGKQLEDEIEK 1580



 Score = 71.7 bits (168), Expect = 2e-10
 Identities = 138/668 (20%), Positives = 269/668 (40%), Gaps = 59/668 (8%)

Query: 143  DVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXX 202
            D+ + SN+ KE       L+ K+K  E  +  L  K   + +I++      +        
Sbjct: 1388 DIAYASNSSKEMQTKNENLETKLKSTEKDLSTLNSKFTNETKILK---DLISDHEVSISS 1444

Query: 203  XXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEA 262
                     ++ +++   + EN   +  E+ D+    +K++E K + I+     +K L A
Sbjct: 1445 LKVDLDKKVQEVEKERNMLSENSETVIKEYGDK----IKELE-KALGIAKTAHESK-LNA 1498

Query: 263  ARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMT 322
               E  L    L     +              L K+ IE S   K E E K  L  + ++
Sbjct: 1499 MSKEKKLADESLKYINNEFEIHKNDSNESTTKLTKE-IE-SLNVKLENERK--LSTSKLS 1554

Query: 323  ELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVS----------SPSKK--GSPLI 370
            E  ++ EL +     ++ T K+LE+++  +  E   VS          S  +K   S + 
Sbjct: 1555 E--REAELKKESE-TLKATGKQLEDEIEKLKKEKDVVSDNFQLKNLEFSTLEKDLASKVE 1611

Query: 371  SRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISE 430
              KS  N     K     + S+T   + D +  +    K +  + +LN+ + + + V S 
Sbjct: 1612 EIKSINNVTESYKKESDDIKSKTKQLENDLEAAQKFGDKTKEELDTLNQKIEELKSVNSN 1671

Query: 431  KDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELN 490
             +            K++  +   L+ Q+      L  + ++ +  +E+ K  E   Q L 
Sbjct: 1672 TEETWTNKL-----KESESSYAALDEQKKSISQELSALKSSDKAASEMTKQLENELQTLK 1726

Query: 491  DEI--KDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFS 548
            D+I  K  + K+L EK  +    I +L +++DA  K +   KS                 
Sbjct: 1727 DDIEEKSRSKKELEEKSTTLSSTINELENKLDAMKKELDSEKS--------------VIE 1772

Query: 549  KVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENL 608
            K+S   KE  +L+ +L    +K  +LE+E   L+     +D+   I  +  K++    + 
Sbjct: 1773 KLSAELKEHSKLSADLKEYKEKFEQLEKEHEQLK---KKFDAEGNIHGEKMKELKSKLDS 1829

Query: 609  AETRLKAISLLESQKFDLVQE-LHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQ 667
             +  L A   L+S+   L QE L     K DE++    D+   Q+ +   +     L   
Sbjct: 1830 LQDDLTAAMDLKSKIESLNQELLSTKTTKDDEIKKLTKDLESTQALKNNEKELKKDLNSS 1889

Query: 668  IDALSASKKELALVIEN---LKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKL 724
             + +S  K++L  + EN   LK D E        L  + E + +  +N  ++N+D   + 
Sbjct: 1890 KENISTLKEDLNALKENETRLKQDLEISKANEDSLNKELESLKSSQKNKEKDNIDFDSQK 1949

Query: 725  EKM--SAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLE 782
                 S +K+ E +  +  + + +  T     +++ +  L + +I+    KYK ++  L 
Sbjct: 1950 ANFLESEKKLKEEVEALKKKLKEQSSTMVP-RSELDDLMLLMSDIDEHNKKYKKQLKALG 2008

Query: 783  ESIAVMED 790
            + I+  E+
Sbjct: 2009 QDISSDEE 2016


>UniRef50_UPI000150A61D Cluster: hypothetical protein TTHERM_00370670;
            n=1; Tetrahymena thermophila SB210|Rep: hypothetical
            protein TTHERM_00370670 - Tetrahymena thermophila SB210
          Length = 1534

 Score =  144 bits (350), Expect = 1e-32
 Identities = 272/1358 (20%), Positives = 571/1358 (42%), Gaps = 118/1358 (8%)

Query: 91   SESLANTLKQKEI-LMEKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSN 149
            S+ +   L++ ++ +  K  Q  +  ++  + I R               Q   +  L +
Sbjct: 196  SKQMYEALQKAQVEIKNKESQMNQFIEQQRSEIKRSYDQEIQIFKETILKQEQQINSLQD 255

Query: 150  -TIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXX 208
             + K+ +N  +  + ++ ++ T +  LQ+ INEK+ +I    + T               
Sbjct: 256  LSAKKNENETNRFEERVALLTTELERLQQIINEKNSMISKLEEKTAMFTQEIERLKLM-- 313

Query: 209  XXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEIS 268
               ++ K Q+    E   A+  +  +  Q +++    K V+ +S +E  K  E       
Sbjct: 314  ---QNEKNQVNLKLEEKCAIFTQEINRLQMIIQS-NQKQVQEASSQELQKYEERVYI--- 366

Query: 269  LEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKI 328
            LE  KL   + Q              +  +  E      TEI+    +  +   +  +++
Sbjct: 367  LEQEKLT--IIQDVHKLAEESQRLNEINSKLEEKVAGFSTEIDRLNMMLQSRQNQYEERV 424

Query: 329  ELL----EHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNT-ASKMK 383
              L    E LN  I+Q     E K+  + TE   ++    K   +I +++  N   +K +
Sbjct: 425  TNLTVEIERLNALIQQRTTHFEEKIVQLTTEITHLNE--SKNILIIEKQNLMNDYKNKHE 482

Query: 384  SPWSQLSSETLNQDTDKKINKNEIAKLEMVIQS---LNKDLVDKEYVISEKDTXXXXXXX 440
                Q++ E    +      + ++A+ E  ++     +KD++D+E    E          
Sbjct: 483  DKIGQMTQEISRLNQVICQLEGQVAENEETVKRSKHTHKDVLDQERANFELINTKQNHRI 542

Query: 441  XXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKD 500
                 +   AQ++++  Q       I+      D ++ A++   L +E+ + ++ +N   
Sbjct: 543  IELENEKKFAQMEIQRLQER-----INDAQMERDKSQSAELA--LNREI-ENLQCIN-NS 593

Query: 501  LIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRL 560
               ++++  E+I  L  E     + + ++KS++++ ++Q   T +        N E  + 
Sbjct: 594  RQREIETLHERIRVLEKE---GEQRVSEMKSHYEM-MRQSHITREVQELTIKFNSERKQF 649

Query: 561  TEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEM-------ENLAETRL 613
              ++ +  Q   ELE    NLQ+   + D  R +     K++ E+       +N  ET +
Sbjct: 650  ETQISNQFQNNRELEN---NLQIITAETDRLRQLCETKTKEIEELKQTELLQQNKMETYI 706

Query: 614  KAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSA 673
              I  L S   D   +L +LQ+   E++ +     Q++ +Q   E++     EQ   L+ 
Sbjct: 707  IQIQKLNSDLQDSKNQLVVLQE---EMQRQFERQKQIELEQFERELRR-DFSEQYGQLNY 762

Query: 674  SKKELALVIENLKLD---KEQLYGTIKDLENDK--ED--IMNKLQNYI----QENMDLTD 722
              ++++L  E   +    +   +  IKD +N+K  ED  ++ + +  I    QE   L  
Sbjct: 763  KLQDMSLKYEESLVAYVLQSTEFERIKD-QNEKLWEDNCVLQQKEEQIKIEFQEEFTLYK 821

Query: 723  -KLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRL 781
             ++E+ + EK+   L +I +E+    Q Q+  +   Q+ +L+  N ++E+++Y++ +   
Sbjct: 822  VEIERANREKLEIELKEI-YEKIEFQQQQYNNELNKQQTELH--NQQNEINRYQNELNAA 878

Query: 782  EESIAVMEDRRYSLERKADQLGS-------YLQEKQKAYSEYTIQEDELVNRLAVLMDHD 834
             E I  + D +  LE K   L +        +QEK K  S+  ++ + L           
Sbjct: 879  LEQIKELHDNKDELENKIVMLSTENNRLVFMIQEKDKKMSQLEVEINHLRETDNTQQSEL 938

Query: 835  RVVEKQLLEIEHENKELQKKNQILLEENQNLQI-------SLSDMQQHYNALVE----KA 883
                 Q  E++   +EL+ K  +L  EN  L          +S  +   N L E    + 
Sbjct: 939  NAALLQRKELQDNIQELENKIVMLSTENNRLVFMIQEKDKKISQQEVEINHLRETDNTQQ 998

Query: 884  NRTDLAESESTKYQTQLRDLESNLKRITHEHQTL--IVQKK-KEIEDLEIEFNTQIESAI 940
            N  + A  +  + Q  +++LE+ +  ++ E+  L  I+Q+K K++   E+E N   E AI
Sbjct: 999  NELNAALLQRKELQDNIQELENKIVMLSTENNRLAFIIQEKDKKLSQQEVEINNLREKAI 1058

Query: 941  R-DKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQ 999
            + + K+   +  K I+   Q +  ++EY  +IE LN  +++LN+   E+ ++    Q+  
Sbjct: 1059 QLEMKIKENESLKQIQ--VQQQCAIEEYVQHIEKLNSQIDQLNRQIQEIQNQFFIDQEEL 1116

Query: 1000 SPDYTEQYINEINKLNALLK-QKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLE 1058
               +  Q  +E+ +L   LK Q ++++ ALN    + +  Y + + D   K    T +LE
Sbjct: 1117 HRQHEFQRQSELEQLERRLKGQFEQQLSALNDTFTDLEDKYQNTLVDVVLK----TAELE 1172

Query: 1059 NMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTE-GMIISST 1117
             M E   ++ + + D   +  E++I   ++    K+  E +   +++  + +    + + 
Sbjct: 1173 RMNELNNKLQQDISDLLTNQNEMEIKFEQEFTVYKQTAEREKQQKVDSERKQIQEKLEAQ 1232

Query: 1118 IEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQ 1177
             +  + + N               L+    EE+ +  +++ ++S KL + +++   +I  
Sbjct: 1233 QQQYNQEINRKQQELKYALEQTRNLE-SNVEEYEKRVTIITQESNKLLSIVEDRENRIRD 1291

Query: 1178 LETLNTELTGHDVVNQ-EQINQ----LKSKLEQLNTENDNLLSTVAELRSSISSAVDQRG 1232
            LET    + G    NQ  Q+ Q    L+ K+E L  +N  L++   E +        Q  
Sbjct: 1292 LETELNNIRGKS--NQISQLKQAELTLQHKIEILQLQNQKLMNDYQECQRQSLEMQIQLS 1349

Query: 1233 FEIAELWKQHLAQREADFQKTEHE----LRVQLSAFESKYEQLLDSVQSSTQE-----ET 1283
             +  E  +  + Q E DF+K  +E    L+ + +   SKY++ L ++   T E     + 
Sbjct: 1350 QKFEEQKRVEMEQFEIDFKKDFNEKYEILQKEFNKLFSKYQECLINIVLITAELEKIKDQ 1409

Query: 1284 NKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXX 1343
            N+ +  + +T  Q + Q +EE      E   +   ++E    EI  +K+ +         
Sbjct: 1410 NEKLWEDNMTLQQREGQFQEEFTAYKMEVEKNCSEKLESELKEIY-QKIEYQQQQYCQQI 1468

Query: 1344 XXXXXXXDLRTENQSYKQM----QEQSILNINEENAQL 1377
                   +   +N +Y Q     QE  I+ ++ EN +L
Sbjct: 1469 NVLQQDLNQANDNTNYLQSLIKEQENKIVLLSTENQRL 1506



 Score =  115 bits (276), Expect = 1e-23
 Identities = 237/1169 (20%), Positives = 482/1169 (41%), Gaps = 92/1169 (7%)

Query: 330  LLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQL 389
            +L H   ++  +NKEL N+L      SK +    +K    I     +N  S+M     Q 
Sbjct: 170  VLAHQYEELMASNKELRNQLNQERETSKQMYEALQKAQVEI-----KNKESQMNQFIEQQ 224

Query: 390  SSETLNQ-DTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTL 448
             SE     D + +I K  I K E  I SL +DL  K+   +E +T           +   
Sbjct: 225  RSEIKRSYDQEIQIFKETILKQEQQINSL-QDLSAKK---NENETNRFE-------ERVA 273

Query: 449  IAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSA 508
            +   +LE  Q +       +    E      +  E+LK   N++   VN+K L EK    
Sbjct: 274  LLTTELERLQQIINEKNSMISKLEEKTAMFTQEIERLKLMQNEK-NQVNLK-LEEKCAIF 331

Query: 509  EEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDN--FSKVSDSNK---EIVRLTEE 563
             ++I +L   I +  K + +  S    K ++    ++    + + D +K   E  RL E 
Sbjct: 332  TQEINRLQMIIQSNQKQVQEASSQELQKYEERVYILEQEKLTIIQDVHKLAEESQRLNEI 391

Query: 564  LHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQK 623
               L +KVA    E   L + L    +    E  V    +E+E L     +  +  E + 
Sbjct: 392  NSKLEEKVAGFSTEIDRLNMMLQSRQN--QYEERVTNLTVEIERLNALIQQRTTHFEEKI 449

Query: 624  FDLVQEL-HILQQK---YDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELA 679
              L  E+ H+ + K     E ++ + D      D++    + +    Q+  +   + ++A
Sbjct: 450  VQLTTEITHLNESKNILIIEKQNLMNDYKNKHEDKIGQMTQEISRLNQV--ICQLEGQVA 507

Query: 680  LVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKI 739
               E +K  K   +  + D E    +++N  QN+    ++   K  +M  +++ E   +I
Sbjct: 508  ENEETVKRSKHT-HKDVLDQERANFELINTKQNHRIIELENEKKFAQMEIQRLQE---RI 563

Query: 740  NHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKA 799
            N  +  + ++Q    A  +E    IEN++   +  +  I  L E I V+E      E++ 
Sbjct: 564  NDAQMERDKSQSAELALNRE----IENLQCINNSRQREIETLHERIRVLEKEG---EQRV 616

Query: 800  DQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRV-VEKQLLEIEHENKELQKKNQIL 858
             ++ S+ +  ++++    +QE      L +  + +R   E Q+      N+EL+   QI+
Sbjct: 617  SEMKSHYEMMRQSHITREVQE------LTIKFNSERKQFETQISNQFQNNRELENNLQII 670

Query: 859  LEENQNLQISLSDMQQHYNALVEKANRTDLAESESTK-YQTQLRDLESNLKRITHEHQTL 917
              E   L+     + +     +E+  +T+L +    + Y  Q++ L S+L+   ++   L
Sbjct: 671  TAETDRLR----QLCETKTKEIEELKQTELLQQNKMETYIIQIQKLNSDLQDSKNQLVVL 726

Query: 918  IVQKKKEIE---DLEIE-FNTQIESAIRDKK-VLNEKYEK-NIEYVTQLEAQLQEYKNNI 971
              + +++ E    +E+E F  ++     ++   LN K +  +++Y   L A + +     
Sbjct: 727  QEEMQRQFERQKQIELEQFERELRRDFSEQYGQLNYKLQDMSLKYEESLVAYVLQ-STEF 785

Query: 972  ENLNMNVEELNKMNLELIDKHVQKQQTQSPDYT--EQYINEIN--KLNALLKQKDEEIIA 1027
            E +    E+L + N  L  K  Q +     ++T  +  I   N  KL   LK+  E+I  
Sbjct: 786  ERIKDQNEKLWEDNCVLQQKEEQIKIEFQEEFTLYKVEIERANREKLEIELKEIYEKIEF 845

Query: 1028 LNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRV--SKQLLDSK-----QHNEE 1080
              Q+ NN      + + + ++++ ++  +L    E+++ +  +K  L++K       N  
Sbjct: 846  QQQQYNNELNKQQTELHNQQNEINRYQNELNAALEQIKELHDNKDELENKIVMLSTENNR 905

Query: 1081 LQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXX 1140
            L  +++E+D ++ +L E ++        T+   +++ +    +  +N+            
Sbjct: 906  LVFMIQEKDKKMSQL-EVEINHLRETDNTQQSELNAALLQRKELQDNIQELENKIVMLST 964

Query: 1141 XLKVQEEEEFIQERSV-LQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQL 1199
              +       IQE+   + +Q  ++N  L+E  T   Q   LN  L     + Q+ I +L
Sbjct: 965  --ENNRLVFMIQEKDKKISQQEVEIN-HLRE--TDNTQQNELNAALLQRKEL-QDNIQEL 1018

Query: 1200 KSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEH--EL 1257
            ++K+  L+TEN+ L   + E    +S    Q+  EI  L ++   Q E   ++ E   ++
Sbjct: 1019 ENKIVMLSTENNRLAFIIQEKDKKLS----QQEVEINNL-REKAIQLEMKIKENESLKQI 1073

Query: 1258 RVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSL-QNKLQDKEEHLRN--LQEKYA 1314
            +VQ      +Y Q ++ + S   +   +I  ++    + Q +L  + E  R   L++   
Sbjct: 1074 QVQQQCAIEEYVQHIEKLNSQIDQLNRQIQEIQNQFFIDQEELHRQHEFQRQSELEQLER 1133

Query: 1315 DVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQ-SILNINEE 1373
             +  Q E   S + D                     +L   N+   ++Q+  S L  N+ 
Sbjct: 1134 RLKGQFEQQLSALNDTFTDLEDKYQNTLVDVVLKTAELERMNELNNKLQQDISDLLTNQN 1193

Query: 1374 NAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDE 1433
              ++K               +    +++  ++  +LE +  +  Q+ +     L    ++
Sbjct: 1194 EMEIKFEQEFTVYKQTAEREKQQKVDSERKQIQEKLEAQQQQYNQEINRKQQELKYALEQ 1253

Query: 1434 FENVRQQLVEYEKRIEDLTYEKESELAIL 1462
              N+   + EYEKR+  +T E    L+I+
Sbjct: 1254 TRNLESNVEEYEKRVTIITQESNKLLSIV 1282



 Score = 81.8 bits (193), Expect = 1e-13
 Identities = 170/812 (20%), Positives = 334/812 (41%), Gaps = 75/812 (9%)

Query: 813  YSEYTIQEDELVNRLAVLMDHDRVVEKQLLE-IEHENKELQKKNQILLEENQNLQISLSD 871
            Y E      EL N+L    + +R   KQ+ E ++    E++ K     + NQ ++   S+
Sbjct: 175  YEELMASNKELRNQL----NQERETSKQMYEALQKAQVEIKNKES---QMNQFIEQQRSE 227

Query: 872  MQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIE 931
            +++ Y+  ++    T L      K + Q+  L+ +L    +E++T   +++  +   E+E
Sbjct: 228  IKRSYDQEIQIFKETIL------KQEQQINSLQ-DLSAKKNENETNRFEERVALLTTELE 280

Query: 932  FNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEE---LNKMNLEL 988
               +++  I +K  +  K E+     TQ   +L+  +N    +N+ +EE   +    +  
Sbjct: 281  ---RLQQIINEKNSMISKLEEKTAMFTQEIERLKLMQNEKNQVNLKLEEKCAIFTQEINR 337

Query: 989  IDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYES 1048
            +   +Q  Q Q  + + Q + +  +   +L+Q+   II    K+         + S  E 
Sbjct: 338  LQMIIQSNQKQVQEASSQELQKYEERVYILEQEKLTIIQDVHKLAEESQRLNEINSKLEE 397

Query: 1049 KLAQFTTKLENMEEEMQ----RVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEM 1104
            K+A F+T+++ +   +Q    +  +++ +     E L  L++++    +E K  +LT E+
Sbjct: 398  KVAGFSTEIDRLNMMLQSRQNQYEERVTNLTVEIERLNALIQQRTTHFEE-KIVQLTTEI 456

Query: 1105 -NIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLK--VQEEEEFIQERSVLQEQS 1161
             ++ +++ ++I      M+D  N  +            L   + + E  + E     ++S
Sbjct: 457  THLNESKNILIIEKQNLMNDYKNKHEDKIGQMTQEISRLNQVICQLEGQVAENEETVKRS 516

Query: 1162 AKLNTELQECYTKIIQLETLNT-------ELTGHDVVNQEQINQLKSKLEQLNTENDNLL 1214
               + ++ +   +    E +NT       EL       Q +I +L+ ++     E D   
Sbjct: 517  KHTHKDVLD--QERANFELINTKQNHRIIELENEKKFAQMEIQRLQERINDAQMERDKSQ 574

Query: 1215 STVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDS 1274
            S    L   I +          E+   H  +R    +K E E RV  S  +S YE +  S
Sbjct: 575  SAELALNREIENLQCINNSRQREIETLH--ERIRVLEK-EGEQRV--SEMKSHYEMMRQS 629

Query: 1275 -VQSSTQEETNKIVTMEQV--TSLQNKLQDKEEHLRNLQEKYA--DVINQI-EILRSEIE 1328
             +    QE T K  +  +   T + N+ Q+  E   NLQ   A  D + Q+ E    EIE
Sbjct: 630  HITREVQELTIKFNSERKQFETQISNQFQNNRELENNLQIITAETDRLRQLCETKTKEIE 689

Query: 1329 DEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXX 1388
            + K                    ++  N   +  + Q ++   E   Q ++         
Sbjct: 690  ELK----QTELLQQNKMETYIIQIQKLNSDLQDSKNQLVVLQEEMQRQFERQKQIELEQF 745

Query: 1389 XXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRI 1448
                 R  D   +  +L ++L+    ++  K  E  +    ++ EFE ++ Q    EK  
Sbjct: 746  ERELRR--DFSEQYGQLNYKLQ----DMSLKYEESLVAYVLQSTEFERIKDQ---NEKLW 796

Query: 1449 EDLTYEKESELAILRLKMHENANHY----ETMQKES-EIERVKLIEELNVKITE-SVSLN 1502
            ED    ++ E  I +++  E    Y    E   +E  EIE  ++ E++  +  + +  LN
Sbjct: 797  EDNCVLQQKEEQI-KIEFQEEFTLYKVEIERANREKLEIELKEIYEKIEFQQQQYNNELN 855

Query: 1503 KQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFAS 1562
            KQ  EL+    E     NE+  ALE    +I  L+D    L+N +   S++  + V F  
Sbjct: 856  KQQTELHNQQNEINRYQNELNAALE----QIKELHDNKDELENKIVMLSTENNRLV-FMI 910

Query: 1563 DTKQGRDEQLDNTMNK-ELLDAVPRAELDLAM 1593
              K  +  QL+  +N     D   ++EL+ A+
Sbjct: 911  QEKDKKMSQLEVEINHLRETDNTQQSELNAAL 942



 Score = 78.2 bits (184), Expect = 2e-12
 Identities = 171/885 (19%), Positives = 358/885 (40%), Gaps = 69/885 (7%)

Query: 706  IMNKLQNYIQENMDLTDKL--EKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLY 763
            + ++ +  +  N +L ++L  E+ +++++ E L K   E ++K ++Q     + Q+R   
Sbjct: 171  LAHQYEELMASNKELRNQLNQERETSKQMYEALQKAQVEIKNK-ESQMNQFIE-QQRSEI 228

Query: 764  IENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDEL 823
              + + E+  +K  I + E+ I  ++D   S ++  ++   + +      +E    +  +
Sbjct: 229  KRSYDQEIQIFKETILKQEQQINSLQD--LSAKKNENETNRFEERVALLTTELERLQQII 286

Query: 824  VNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKA 883
              + +++   +        EIE       +KNQ+ L+  +   I   ++ +    ++ ++
Sbjct: 287  NEKNSMISKLEEKTAMFTQEIERLKLMQNEKNQVNLKLEEKCAIFTQEINRLQ--MIIQS 344

Query: 884  NRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDK 943
            N+  + E+ S     +L+  E  +  +  E  T+I    K  E+ +   N +I S + +K
Sbjct: 345  NQKQVQEASSQ----ELQKYEERVYILEQEKLTIIQDVHKLAEESQ-RLN-EINSKLEEK 398

Query: 944  KVLNEKYEKNIEYVTQ-LEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPD 1002
                  +   I+ +   L+++  +Y+  + NL + +E LN +        +Q++ T   +
Sbjct: 399  VA---GFSTEIDRLNMMLQSRQNQYEERVTNLTVEIERLNAL--------IQQRTTHFEE 447

Query: 1003 YTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENM-- 1060
               Q   EI  LN        E   L     N     +  ++   S+L Q   +LE    
Sbjct: 448  KIVQLTTEITHLNESKNILIIEKQNLMNDYKNKHEDKIGQMTQEISRLNQVICQLEGQVA 507

Query: 1061 --EEEMQR---VSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIIS 1115
              EE ++R     K +LD ++ N EL  +  +Q+ +I EL+  K   +M I + +  I  
Sbjct: 508  ENEETVKRSKHTHKDVLDQERANFEL--INTKQNHRIIELENEKKFAQMEIQRLQERIND 565

Query: 1116 STIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQER-SVLQEQSAKLNTELQECYTK 1174
            + +E     +  +                Q E E + ER  VL+++  +  +E++  Y  
Sbjct: 566  AQMERDKSQSAELALNREIENLQCINNSRQREIETLHERIRVLEKEGEQRVSEMKSHYEM 625

Query: 1175 IIQLETLNT--ELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRG 1232
            + Q        ELT      ++Q     S   Q N E +N L  +      +    + + 
Sbjct: 626  MRQSHITREVQELTIKFNSERKQFETQISNQFQNNRELENNLQIITAETDRLRQLCETKT 685

Query: 1233 FEIAELWKQHLAQRE-------------ADFQKTEHELRVQLSAFESKYEQLLDSVQSST 1279
             EI EL +  L Q+              +D Q ++++L V     + ++E+         
Sbjct: 686  KEIEELKQTELLQQNKMETYIIQIQKLNSDLQDSKNQLVVLQEEMQRQFERQKQIELEQF 745

Query: 1280 QEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXX 1339
            + E  +  + EQ   L  KLQD    L+  +   A V+   E  R + ++EK+       
Sbjct: 746  ERELRRDFS-EQYGQLNYKLQDMS--LKYEESLVAYVLQSTEFERIKDQNEKL--WEDNC 800

Query: 1340 XXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAE 1399
                       + + E   YK   E++  N  +   +LK+               +N  +
Sbjct: 801  VLQQKEEQIKIEFQEEFTLYKVEIERA--NREKLEIELKEIYEKIEFQQQQYNNELNKQQ 858

Query: 1400 AKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESEL 1459
             ++    +++    +E+     E    L    DE EN    L     R+  +  EK+ ++
Sbjct: 859  TELHNQQNEINRYQNEL-NAALEQIKELHDNKDELENKIVMLSTENNRLVFMIQEKDKKM 917

Query: 1460 AILRLKMHENANHYETMQKESE---IERVKL---IEELNVKI----TESVSLNKQVAELN 1509
            + L ++++       T Q E     ++R +L   I+EL  KI    TE+  L   + E +
Sbjct: 918  SQLEVEINHLRETDNTQQSELNAALLQRKELQDNIQELENKIVMLSTENNRLVFMIQEKD 977

Query: 1510 KALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKI 1554
            K + ++  + N ++     Q+ E+     +   LQ+ ++   +KI
Sbjct: 978  KKISQQEVEINHLRETDNTQQNELNAALLQRKELQDNIQELENKI 1022



 Score = 58.4 bits (135), Expect = 2e-06
 Identities = 140/733 (19%), Positives = 306/733 (41%), Gaps = 88/733 (12%)

Query: 846  HENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLES 905
            HE K++Q  N I  + N    I+ +     +N+ +   + + + ++++   Q ++  L++
Sbjct: 66   HEQKQIQANNNI--QTNTVTTITRTSRTLSFNSSLNTGS-SQIYQNQNQPIQHKVPFLQT 122

Query: 906  -----NLKRITHEHQTLIVQKKKEIEDLEI-EFNTQ--IESAIRDKKVLNEKYEKNIEYV 957
                 NL     +  TL  Q+     +  I   N+Q  I     ++ VL  +YE+ +   
Sbjct: 123  QQSSGNLANPLLQSGTLNHQRHTSCNNSTILSENSQRGIIFNAPNQGVLAHQYEELMASN 182

Query: 958  TQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINK-LNA 1016
             +L  QL + +   + +    E L K  +E+ +K  Q  Q     + EQ  +EI +  + 
Sbjct: 183  KELRNQLNQERETSKQM---YEALQKAQVEIKNKESQMNQ-----FIEQQRSEIKRSYDQ 234

Query: 1017 LLKQKDEEIIALNQKINNAQ----VSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQL- 1071
             ++   E I+   Q+IN+ Q        +  + +E ++A  TT+LE +++ +   +  + 
Sbjct: 235  EIQIFKETILKQEQQINSLQDLSAKKNENETNRFEERVALLTTELERLQQIINEKNSMIS 294

Query: 1072 -LDSK-----QHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDA 1125
             L+ K     Q  E L+++  E++    +L+E    F   I + + MII S  + + + +
Sbjct: 295  KLEEKTAMFTQEIERLKLMQNEKNQVNLKLEEKCAIFTQEINRLQ-MIIQSNQKQVQEAS 353

Query: 1126 NNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTEL 1185
            +               +  QE+   IQ+   L E+S +LN    +   K+      +TE+
Sbjct: 354  SQ----ELQKYEERVYILEQEKLTIIQDVHKLAEESQRLNEINSKLEEKVAGF---STEI 406

Query: 1186 TGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQ 1245
               +++ Q + NQ + ++  L  E + L + + +  +     + Q   EI      HL +
Sbjct: 407  DRLNMMLQSRQNQYEERVTNLTVEIERLNALIQQRTTHFEEKIVQLTTEIT-----HLNE 461

Query: 1246 READFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVT-SLQNKLQDKEE 1304
             +      +  L   ++ +++K+E   D +   TQE    I  + QV   L+ ++ + EE
Sbjct: 462  SKNILIIEKQNL---MNDYKNKHE---DKIGQMTQE----ISRLNQVICQLEGQVAENEE 511

Query: 1305 HLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQE 1364
             ++  +  + DV++Q          E+  F                + +      +++QE
Sbjct: 512  TVKRSKHTHKDVLDQ----------ERANFELINTKQNHRIIELENEKKFAQMEIQRLQE 561

Query: 1365 QSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYT 1424
            +  +N  +      +S+             +N++  + +E  H+       + +K  E  
Sbjct: 562  R--INDAQMERDKSQSAELALNREIENLQCINNSRQREIETLHER----IRVLEKEGEQR 615

Query: 1425 ITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIER 1484
            ++  +    +E +RQ  +  E  +++LT           +K +     +ET Q  ++ + 
Sbjct: 616  VS--EMKSHYEMMRQSHITRE--VQELT-----------IKFNSERKQFET-QISNQFQN 659

Query: 1485 VKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQ-TALENQEIEIVTLNDEITNL 1543
             + +E     IT      +Q+ E      EE+ +T  +Q   +E   I+I  LN ++ + 
Sbjct: 660  NRELENNLQIITAETDRLRQLCETKTKEIEELKQTELLQQNKMETYIIQIQKLNSDLQDS 719

Query: 1544 QNMVRASSSKIQK 1556
            +N +     ++Q+
Sbjct: 720  KNQLVVLQEEMQR 732


>UniRef50_Q1FIV0 Cluster: Putative uncharacterized protein; n=1;
            Clostridium phytofermentans ISDg|Rep: Putative
            uncharacterized protein - Clostridium phytofermentans
            ISDg
          Length = 1361

 Score =  144 bits (349), Expect = 2e-32
 Identities = 290/1407 (20%), Positives = 603/1407 (42%), Gaps = 143/1407 (10%)

Query: 233  KDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXX 292
            K EKQR+L+  +  +  + ++EE +K  +  R  +     K  QE++Q            
Sbjct: 5    KQEKQRMLEMEQGYENSLLTIEELSKSYKENRALL----EKREQEMKQLLQKVSYFQSEI 60

Query: 293  XXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATM 352
                + + E     K E E++ S   +++ +   K+++L      +  T KE +     +
Sbjct: 61   AKYNEITTEVEAYVK-EREDQISRLNSDIGDYESKLKILRLDKDSLSSTIKEKQKAYYEL 119

Query: 353  GTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINK--NEIAKL 410
              + KA+    ++ +     ++  N   ++     +  SET+  + + +I+K    +  L
Sbjct: 120  EDKLKAIE--EERSAEKEKLEANENQIKELAKLLEE--SETIFTEKEGEISKLSENVKIL 175

Query: 411  EMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVG- 469
            E+ ++     + +K  +I   +               LI +L+LE ++  +    + V  
Sbjct: 176  ELELEEKTSIVKNKVDLIHGLENEEKKQKEELIQNKALIEKLKLECERAKKSQEELAVQF 235

Query: 470  TNTEDVNEIAKVQ-EQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIK 528
             +TE   E  K +   LK++L +  K++    L+E +K+ + ++ Q  D  +   K +++
Sbjct: 236  KDTEAKYEQGKNEIRTLKEQLKN--KELEHNKLLENIKNLQNKLNQSVDNHENIKKELLQ 293

Query: 529  VKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDY 588
             KS+    +++++K  +  ++    N  I RL EE          LEE K   Q H +  
Sbjct: 294  SKSH----IQELEKEKEILTE--GHNDLINRLEEETGKNQGLNNSLEELK--TQSHHMKQ 345

Query: 589  DSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADIS 648
            +    +E    + ++++  + E       L E QK  L++E +IL QK D +        
Sbjct: 346  E----LEKASSENLLKVHEIGECSNLIEELNEKQK-TLLEEFNILSQKQDSL-------- 392

Query: 649  QLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLE-------N 701
             ++ +++ ++ + +  E  ++  +  K++L   +E+L+++ E L   + DLE        
Sbjct: 393  SMEKEKLFTDKEKI--ESLLNNSNNEKEQLTKRLESLRIEAENLTSKVNDLEELLELSGE 450

Query: 702  DKEDIMNKLQNYIQENMDLTDKLEKMSAEKISEL--LAKINHEEQSKIQTQFGID-AKIQ 758
            D   +  KL+  I+E+  L ++ + +  +  SE+  L +  +EE+ +I+ +F  +   ++
Sbjct: 451  DAVQVSEKLKQAIEESNKLLEEKDTVIKQAYSEIETLKEKFNEEKLEIEDKFEHEILSLK 510

Query: 759  ERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKAD-QLGSYLQEKQKAYSEYT 817
            E+    EN E E  K K+    LEE I+  E  +  +  KA+ +L  Y    ++   E  
Sbjct: 511  EQ----ENQEKEKIKVKAE-QELEEYISFAEKAKDEIRSKAELELEEYKNLVKQEKEELR 565

Query: 818  IQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYN 877
            ++ ++ +     L +     EK+ ++ + E +E+++   + +++ +++++      + Y 
Sbjct: 566  VKAEQELEEYMTLAEK----EKEDIKTQAE-QEIEEYKNLAMQDKEDIKVKAEQELEEYM 620

Query: 878  ALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIE 937
             L EK       E +  K Q + R++E        E++ L +Q K   ED++++   ++E
Sbjct: 621  TLAEK-------EKDDIKTQAE-REIE--------EYKNLAMQDK---EDIKVKAEQELE 661

Query: 938  SAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIE----NLNMNVEELNKMNLELIDKHV 993
                +   L EK EK+ E   Q E +L+EYK  ++     L +  E+  +  + L +K  
Sbjct: 662  ----EYMTLAEK-EKD-EIRKQAELELEEYKELVKQEKVELKVKAEQELEEYIALAEKEK 715

Query: 994  QKQQTQSPDYTEQYINEINK----LNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESK 1049
            +  + Q+    E+Y    NK    +    +Q+ EE IAL +K   A ++      +  +K
Sbjct: 716  EDIRKQAEQEIEEYKKLANKEKEEIKVKAEQELEEYIALAEKEKEAIIAQSEQEFEEHAK 775

Query: 1050 LAQFTTK--LENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIP 1107
            L     +   EN  +  + + +Q++   Q  E L+  +    ++    +      E  + 
Sbjct: 776  LVSLKQEELQENARKGQKLLEEQIVAEVQEKEHLKKQIENSREKETNFESRIRELEELLE 835

Query: 1108 KTEGMI--ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLN 1165
             +EG +  IS  ++   ++   +                +E+E+   E   + E+  KL 
Sbjct: 836  LSEGEVSEISEKLKQSEEEKEAIKVNSESELEAYKKQTEKEKEDIKSEADRVIEEYKKLA 895

Query: 1166 TELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSIS 1225
             + QE Y K+++ E    E     V  ++++ + K   EQ   + DN      EL     
Sbjct: 896  EDGQEEYKKLLEQE---KEYNKFQV--EQELEKYKKLAEQ--EKEDNKFQAAQELEKYKK 948

Query: 1226 SAVDQR---GFEIA---ELWKQHLAQREADFQ-KTEHELRVQLSAFESKYEQLLDSVQSS 1278
             A  ++    F+ A   EL+K+ + + + + +   E EL  Q    E +  ++++     
Sbjct: 949  LAEQEKENIKFQTAQELELYKKLVEKEKEEIKANAEQELEEQKKEAEQEKNEIIEQAVQE 1008

Query: 1279 TQEETNKIVTME-----QVTSLQNKLQDKE--------EHLRNLQEKYADVINQIEILRS 1325
              EE  K+V +E     +    + KL +++        E LR L E   +    ++   S
Sbjct: 1009 L-EEIKKLVAIEAEEIIETAKKEKKLLEEQVASGFLEKEQLRELFESQNNEEKCLKSKLS 1067

Query: 1326 EIEDE---KVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSX 1382
            E+ED                        DLR ENQ   Q Q  + LN+ EE  + +  S 
Sbjct: 1068 ELEDHIELTNEELINLNEKLNQSEFENKDLREENQ-LLQEQANNKLNLLEEKYEKEIDSL 1126

Query: 1383 XXXXXXXXXXXRVNDAEAKVL----ELTHQLELKDSEIYQKTHEYTITLTQRNDEFENV- 1437
                        + + + K+L    E  +QLE K  +I Q+       +T++ ++ + + 
Sbjct: 1127 KASEQKVLDYELLINEKDKLLGQRKEQIYQLEQKLCKINQEDVTKANDITEKQEQLDRLI 1186

Query: 1438 -RQQLVEYE-KRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKI 1495
              Q+++  E KR +++  + E +L     +  +N       QK+  +   KL  E    I
Sbjct: 1187 SDQEVLSNEVKRAQEIISQLEEKLN--EGESEKNTLLSTLDQKDLIMNSAKLALEKQRDI 1244

Query: 1496 TESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQ 1555
            +   ++N  +A+    +EE+     ++    E  + + + L  EIT L+ M    ++K +
Sbjct: 1245 SIEQTIN--LAKHKDRIEEQTKVIQQLVDNNEELQQKYIILTTEITELKKM---DAAKRE 1299

Query: 1556 KHVSFASD-TKQGRDEQLDNTMNKELL 1581
              V    D  K+   E+  +T+N E L
Sbjct: 1300 IDVGKEHDAVKEHAAEREHDTINDEKL 1326



 Score =  142 bits (345), Expect = 5e-32
 Identities = 274/1297 (21%), Positives = 543/1297 (41%), Gaps = 107/1297 (8%)

Query: 92   ESLANTLKQKEILMEKIKQYKELS-KRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNT 150
            +SL++T+K+K+      K Y EL  K  +    R               +L  +   S T
Sbjct: 103  DSLSSTIKEKQ------KAYYELEDKLKAIEEERSAEKEKLEANENQIKELAKLLEESET 156

Query: 151  I-KEKDNALSVLQVKMKIMETTILDLQEKI----NEKDQI--IEAKNKATTXXXXXXXXX 203
            I  EK+  +S L   +KI+E   L+L+EK     N+ D I  +E + K            
Sbjct: 157  IFTEKEGEISKLSENVKILE---LELEEKTSIVKNKVDLIHGLENEEKKQKEELIQNKAL 213

Query: 204  XXXXXXXXEDTKQQMTKMQENFIAMEAEW---KDEKQRLLKDIESKDVRISSLEEANKLL 260
                    E  K+   ++   F   EA++   K+E + L + +++K++  + L E  K L
Sbjct: 214  IEKLKLECERAKKSQEELAVQFKDTEAKYEQGKNEIRTLKEQLKNKELEHNKLLENIKNL 273

Query: 261  EAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAK----------------QSIEPSC 304
            +    +    H  + +EL Q              L +                Q +  S 
Sbjct: 274  QNKLNQSVDNHENIKKELLQSKSHIQELEKEKEILTEGHNDLINRLEEETGKNQGLNNSL 333

Query: 305  EE-KTEIEE-KGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSP 362
            EE KT+    K  LE A+   L K  E+ E  N  I + N++ +  L      S+   S 
Sbjct: 334  EELKTQSHHMKQELEKASSENLLKVHEIGECSNL-IEELNEKQKTLLEEFNILSQKQDSL 392

Query: 363  SKKGSPLISRKSG-RNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDL 421
            S +   L + K    +  +   +   QL+    +   + +   +++  LE +++   +D 
Sbjct: 393  SMEKEKLFTDKEKIESLLNNSNNEKEQLTKRLESLRIEAENLTSKVNDLEELLELSGEDA 452

Query: 422  VDKEYVISEK-DTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAK 480
            V     +SEK              KDT+I Q   E +   E  +   +    +  +EI  
Sbjct: 453  VQ----VSEKLKQAIEESNKLLEEKDTVIKQAYSEIETLKEKFNEEKLEIEDKFEHEILS 508

Query: 481  VQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAA---NKNMIKVKSNHKLKL 537
            ++EQ  QE  ++IK    ++L E +  AE+   ++  + +      KN++K +   +L++
Sbjct: 509  LKEQENQE-KEKIKVKAEQELEEYISFAEKAKDEIRSKAELELEEYKNLVK-QEKEELRV 566

Query: 538  KQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQK---VAELEEEKGNLQLHLVDYDSGRMI 594
            K  Q+ ++ +  +++  KE ++   E      K   + + E+ K   +  L +Y +    
Sbjct: 567  KAEQE-LEEYMTLAEKEKEDIKTQAEQEIEEYKNLAMQDKEDIKVKAEQELEEYMTLAEK 625

Query: 595  ESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQ 654
            E D  K   E E + E +  A+   E  K    QEL       ++ +D++   ++L+ ++
Sbjct: 626  EKDDIKTQAERE-IEEYKNLAMQDKEDIKVKAEQELEEYMTLAEKEKDEIRKQAELELEE 684

Query: 655  VCSEIKSVHLEEQIDALSASKKELALVI---ENLKLDKEQLYGTIKDLEN-DKEDIMNKL 710
                +K   +E ++ A    ++ +AL     E+++   EQ     K L N +KE+I  K 
Sbjct: 685  YKELVKQEKVELKVKAEQELEEYIALAEKEKEDIRKQAEQEIEEYKKLANKEKEEIKVKA 744

Query: 711  QNYIQENMDLTDKLEKM---SAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENI 767
            +  ++E + L +K ++     +E+  E  AK+   +Q ++Q       K+ E  +  E  
Sbjct: 745  EQELEEYIALAEKEKEAIIAQSEQEFEEHAKLVSLKQEELQENARKGQKLLEEQIVAEVQ 804

Query: 768  ESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDEL-VNR 826
            E E    K +I    E     E R   LE   +     + E  +   +   +++ + VN 
Sbjct: 805  EKE--HLKKQIENSREKETNFESRIRELEELLELSEGEVSEISEKLKQSEEEKEAIKVNS 862

Query: 827  LAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNAL-----VE 881
             + L  + +  EK+  +I+ E   + ++ + L E+ Q     L + ++ YN       +E
Sbjct: 863  ESELEAYKKQTEKEKEDIKSEADRVIEEYKKLAEDGQEEYKKLLEQEKEYNKFQVEQELE 922

Query: 882  KANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQK-------KKEIEDLEIEFNT 934
            K  +    E E  K+Q   ++LE   K    E + +  Q        KK +E  + E   
Sbjct: 923  KYKKLAEQEKEDNKFQAA-QELEKYKKLAEQEKENIKFQTAQELELYKKLVEKEKEEIKA 981

Query: 935  QIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHV- 993
              E  + ++K   E+ EKN E + Q   +L+E K  +      + E  K   +L+++ V 
Sbjct: 982  NAEQELEEQKKEAEQ-EKN-EIIEQAVQELEEIKKLVAIEAEEIIETAKKEKKLLEEQVA 1039

Query: 994  ----QKQQT----QSPDYTEQYI-NEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVS 1044
                +K+Q     +S +  E+ + +++++L   ++  +EE+I LN+K+N ++     +  
Sbjct: 1040 SGFLEKEQLRELFESQNNEEKCLKSKLSELEDHIELTNEELINLNEKLNQSEFENKDLRE 1099

Query: 1045 DYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEM 1104
            + +    Q   KL  +EE+ ++    L  S+Q   + ++L+ E+D  + + KE     E 
Sbjct: 1100 ENQLLQEQANNKLNLLEEKYEKEIDSLKASEQKVLDYELLINEKDKLLGQRKEQIYQLEQ 1159

Query: 1105 NIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKL 1164
             + K     ++     +++    +D            +K + +E   Q    L E  ++ 
Sbjct: 1160 KLCKINQEDVTKA-NDITEKQEQLDRLISDQEVLSNEVK-RAQEIISQLEEKLNEGESEK 1217

Query: 1165 NTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSI 1224
            NT L     K + + +    L     ++ EQ   L    +++  E   ++  + +    +
Sbjct: 1218 NTLLSTLDQKDLIMNSAKLALEKQRDISIEQTINLAKHKDRIE-EQTKVIQQLVDNNEEL 1276

Query: 1225 SSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETN 1284
                     EI EL K   A+RE D  K EH+  V+  A E +++ + D       E+ +
Sbjct: 1277 QQKYIILTTEITELKKMDAAKREIDVGK-EHD-AVKEHAAEREHDTIND-------EKLH 1327

Query: 1285 KIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIE 1321
            K     +   L+ KL++K++ +  L+ +  +++ ++E
Sbjct: 1328 K-----EKQLLEMKLEEKDKKIDELETQIIELMVELE 1359



 Score =  140 bits (338), Expect = 4e-31
 Identities = 272/1336 (20%), Positives = 583/1336 (43%), Gaps = 145/1336 (10%)

Query: 143  DVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXX 202
            D   LS+TIKEK  A   L+ K+K +E      +EK+   +  I+   K           
Sbjct: 101  DKDSLSSTIKEKQKAYYELEDKLKAIEEERSAEKEKLEANENQIKELAKLLEESETIFTE 160

Query: 203  XXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEA 262
                     E+ K    +++E    ++      K  L+  +E+++ +       NK L  
Sbjct: 161  KEGEISKLSENVKILELELEEKTSIVK-----NKVDLIHGLENEEKKQKEELIQNKAL-I 214

Query: 263  ARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLE-IANM 321
             + ++  E +K +QE                    ++++   + K E+E    LE I N+
Sbjct: 215  EKLKLECERAKKSQEELAVQFKDTEAKYEQGKNEIRTLKEQLKNK-ELEHNKLLENIKNL 273

Query: 322  -TELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSG-RNTA 379
              +L + ++  E++  ++ Q+   ++         ++  +    +      +  G  N+ 
Sbjct: 274  QNKLNQSVDNHENIKKELLQSKSHIQELEKEKEILTEGHNDLINRLEEETGKNQGLNNSL 333

Query: 380  SKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLN---KDLVDKEYVISEKDTXXX 436
             ++K+    +  E     ++  +  +EI +   +I+ LN   K L+++  ++S+K     
Sbjct: 334  EELKTQSHHMKQELEKASSENLLKVHEIGECSNLIEELNEKQKTLLEEFNILSQK----- 388

Query: 437  XXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDV 496
                    +D+L  + +       +  SL++   N ++  ++ K  E L+ E  +    V
Sbjct: 389  --------QDSLSMEKEKLFTDKEKIESLLNNSNNEKE--QLTKRLESLRIEAENLTSKV 438

Query: 497  NVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKE 556
            N  DL E L+ + E   Q+++++  A +   K+       +KQ    I+   +    N+E
Sbjct: 439  N--DLEELLELSGEDAVQVSEKLKQAIEESNKLLEEKDTVIKQAYSEIETLKE--KFNEE 494

Query: 557  IVRLTEELHH--LSQKVAELEEE---KGNLQLHLVDYDSGRMIESDVYKKMIEMENLAET 611
             + + ++  H  LS K  E +E+   K   +  L +Y S      D  +   E+E L E 
Sbjct: 495  KLEIEDKFEHEILSLKEQENQEKEKIKVKAEQELEEYISFAEKAKDEIRSKAELE-LEEY 553

Query: 612  RLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDAL 671
            +    +L++ +K +L  +     ++Y  + +K  +  + Q++Q   E K++ ++++ D  
Sbjct: 554  K----NLVKQEKEELRVKAEQELEEYMTLAEKEKEDIKTQAEQEIEEYKNLAMQDKEDIK 609

Query: 672  SASKKEL---ALVIENLKLD-KEQLYGTIKDLEN----DKEDIMNKLQNYIQENMDLTDK 723
              +++EL     + E  K D K Q    I++ +N    DKEDI  K +  ++E M L +K
Sbjct: 610  VKAEQELEEYMTLAEKEKDDIKTQAEREIEEYKNLAMQDKEDIKVKAEQELEEYMTLAEK 669

Query: 724  LEKMSAEKISELLAKINHE--EQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRL 781
             EK    K +EL  +   E  +Q K++ +   + +++E     E  + ++ K   +   +
Sbjct: 670  -EKDEIRKQAELELEEYKELVKQEKVELKVKAEQELEEYIALAEKEKEDIRKQAEQ--EI 726

Query: 782  EESIAVMEDRRYSLERKADQ-LGSY--LQEKQK----AYSEYTIQED-ELVN-RLAVLMD 832
            EE   +    +  ++ KA+Q L  Y  L EK+K    A SE   +E  +LV+ +   L +
Sbjct: 727  EEYKKLANKEKEEIKVKAEQELEEYIALAEKEKEAIIAQSEQEFEEHAKLVSLKQEELQE 786

Query: 833  HDR----VVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQ-------HYNALVE 881
            + R    ++E+Q++    E + L+K+ +   E+  N +  + ++++         + + E
Sbjct: 787  NARKGQKLLEEQIVAEVQEKEHLKKQIENSREKETNFESRIRELEELLELSEGEVSEISE 846

Query: 882  KANRTD--------LAESESTKYQTQL----RDLESNLKRITHEHQTLIVQKKKEIEDL- 928
            K  +++         +ESE   Y+ Q      D++S   R+  E++ L    ++E + L 
Sbjct: 847  KLKQSEEEKEAIKVNSESELEAYKKQTEKEKEDIKSEADRVIEEYKKLAEDGQEEYKKLL 906

Query: 929  --EIEFNT-QIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMN 985
              E E+N  Q+E  +   K L E+ +++ ++  Q   +L++YK   E    N++      
Sbjct: 907  EQEKEYNKFQVEQELEKYKKLAEQEKEDNKF--QAAQELEKYKKLAEQEKENIKFQTAQE 964

Query: 986  LELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSD 1045
            LEL  K V+K++ +     EQ + E  K     +Q+  EII   Q +   +     +V+ 
Sbjct: 965  LELYKKLVEKEKEEIKANAEQELEEQKK---EAEQEKNEII--EQAVQELE-EIKKLVAI 1018

Query: 1046 YESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMN 1105
               ++      +E  ++E + + +Q+       E+L+ L   Q+++ K LK      E +
Sbjct: 1019 EAEEI------IETAKKEKKLLEEQVASGFLEKEQLRELFESQNNEEKCLKSKLSELEDH 1072

Query: 1106 IPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQER-----SVLQEQ 1160
            I  T   +I+   +    +  N D              ++EE + +QE+     ++L+E+
Sbjct: 1073 IELTNEELINLNEKLNQSEFENKD--------------LREENQLLQEQANNKLNLLEEK 1118

Query: 1161 SAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAEL 1220
              K    L+    K++  E L  E        +EQI QL+ KL ++N E+    + + E 
Sbjct: 1119 YEKEIDSLKASEQKVLDYELLINEKDKLLGQRKEQIYQLEQKLCKINQEDVTKANDITEK 1178

Query: 1221 RSSISSAVDQRGFEIAELWK--QHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSS 1278
            +  +   +  +     E+ +  + ++Q E    + E E    LS  + K + +++S + +
Sbjct: 1179 QEQLDRLISDQEVLSNEVKRAQEIISQLEEKLNEGESEKNTLLSTLDQK-DLIMNSAKLA 1237

Query: 1279 TQEETNKIVTMEQVTSL---QNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFX 1335
             +++ +  +++EQ  +L   +++++++ + ++ L +   ++  +  IL +EI + K    
Sbjct: 1238 LEKQRD--ISIEQTINLAKHKDRIEEQTKVIQQLVDNNEELQQKYIILTTEITELK---- 1291

Query: 1336 XXXXXXXXXXXXXXXDLRTENQSYKQ-MQEQSILNINEENAQLKKSSXXXXXXXXXXXXR 1394
                           D+  E+ + K+   E+    IN+E  +L K              +
Sbjct: 1292 ------KMDAAKREIDVGKEHDAVKEHAAEREHDTINDE--KLHKEKQLLEMKLEEKDKK 1343

Query: 1395 VNDAEAKVLELTHQLE 1410
            +++ E +++EL  +LE
Sbjct: 1344 IDELETQIIELMVELE 1359



 Score = 84.2 bits (199), Expect = 3e-14
 Identities = 124/601 (20%), Positives = 254/601 (42%), Gaps = 49/601 (8%)

Query: 1017 LLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQ 1076
            L KQ+ + ++ + Q   N+ ++   +   Y+   A    + + M++ +Q+VS    +  +
Sbjct: 3    LSKQEKQRMLEMEQGYENSLLTIEELSKSYKENRALLEKREQEMKQLLQKVSYFQSEIAK 62

Query: 1077 HNE---ELQILVREQDDQIKELKETKLTFE--MNIPKTEGMIISSTIEPMSDDANNVDXX 1131
            +NE   E++  V+E++DQI  L      +E  + I + +   +SSTI+        ++  
Sbjct: 63   YNEITTEVEAYVKEREDQISRLNSDIGDYESKLKILRLDKDSLSSTIKEKQKAYYELE-- 120

Query: 1132 XXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVV 1191
                      LK  EE     ERS  +E+      +++E    + + ET+ TE  G    
Sbjct: 121  --------DKLKAIEE-----ERSAEKEKLEANENQIKELAKLLEESETIFTEKEGEISK 167

Query: 1192 NQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQ 1251
              E +  L+ +LE+  +   N +  +  L +      ++     A + K  L    A  +
Sbjct: 168  LSENVKILELELEEKTSIVKNKVDLIHGLENEEKKQKEELIQNKALIEKLKLECERA--K 225

Query: 1252 KTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIV----TMEQVTSLQNKLQDKEEHLR 1307
            K++ EL VQ    E+KYEQ  + +++  ++  NK +     +E + +LQNKL    ++  
Sbjct: 226  KSQEELAVQFKDTEAKYEQGKNEIRTLKEQLKNKELEHNKLLENIKNLQNKLNQSVDNHE 285

Query: 1308 NLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSI 1367
            N++++     + I+    E+E EK                     +  N S ++++ QS 
Sbjct: 286  NIKKELLQSKSHIQ----ELEKEKEILTEGHNDLINRLEEETGKNQGLNNSLEELKTQS- 340

Query: 1368 LNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITL 1427
             ++ +E  +    +             + +   K   L  +  +    + QK    ++  
Sbjct: 341  HHMKQELEKASSENLLKVHEIGECSNLIEELNEKQKTLLEEFNI----LSQKQDSLSMEK 396

Query: 1428 TQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKL 1487
             +   + E +   L       E LT   ES L I    +    N  E + + S  + V++
Sbjct: 397  EKLFTDKEKIESLLNNSNNEKEQLTKRLES-LRIEAENLTSKVNDLEELLELSGEDAVQV 455

Query: 1488 IEELNVKITESVSLNKQVAELNKALEEEV----AKTNEMQTALENQ-EIEIVTLNDEITN 1542
             E+L   I ES  L ++   + K    E+     K NE +  +E++ E EI++L ++   
Sbjct: 456  SEKLKQAIEESNKLLEEKDTVIKQAYSEIETLKEKFNEEKLEIEDKFEHEILSLKEQENQ 515

Query: 1543 LQNMVRA-SSSKIQKHVSFASDTK-------QGRDEQLDNTMNKELLDAVPRAELDLAMY 1594
             +  ++  +  ++++++SFA   K       +   E+  N + +E  +   +AE +L  Y
Sbjct: 516  EKEKIKVKAEQELEEYISFAEKAKDEIRSKAELELEEYKNLVKQEKEELRVKAEQELEEY 575

Query: 1595 M 1595
            M
Sbjct: 576  M 576


>UniRef50_A2FVB6 Cluster: Putative uncharacterized protein; n=2;
            Trichomonas vaginalis G3|Rep: Putative uncharacterized
            protein - Trichomonas vaginalis G3
          Length = 1684

 Score =  144 bits (349), Expect = 2e-32
 Identities = 232/1182 (19%), Positives = 497/1182 (42%), Gaps = 79/1182 (6%)

Query: 92   ESLANTLKQKEILMEKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTI 151
            + L + LK+K+ ++E+ ++  E         +                +L ++   +  +
Sbjct: 521  KKLNDDLKEKDKIIEENEKNNEQKVSDLKKQIEDLSKQKENENSDVLQKLDNLQKENQKL 580

Query: 152  KEKDNALSVLQVKMKIMETTILDLQ-EKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXX 210
            KE++        K+K     + ++  +K+   D+ +    K                   
Sbjct: 581  KEENEEKESELQKLKQENENLKNIDAQKVTYDDEKVSELQKIIEDLKKENELIQNQKETN 640

Query: 211  XEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDI---ESKDVRISSLEEANKLLEAARF-E 266
              +   ++ K+ E+      + K E  + + D+   E ++  I  L+E N  +E  +  E
Sbjct: 641  DNEKISELQKIVEDLKNENEKLKSEVNQKVTDLQKAEGENDLIKKLQEENLEIENEKDKE 700

Query: 267  ISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTK 326
            IS  + KL +   Q              ++    E + + + EIE +   +   +  L +
Sbjct: 701  ISELNEKLEKLQNQVNNLSSEKVTKDDIISSLQSEVN-DLQEEIESRKDDKQKEINSLKE 759

Query: 327  KIELLEHLNCQIRQTNKE----LENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKM 382
            KIE LE+    ++ +  E    LE +++ +  E   + + ++K S  I     +  +S+ 
Sbjct: 760  KIETLENEKISLQDSMNEEIHKLEEEISNLQNEKSVLETENEKLSKQIEELQEKEKSSQE 819

Query: 383  KSPWSQLSSETLNQDTDK--KINKNEIAKLEMVIQSLNKDLVD----KEYVISEKDTXXX 436
            ++      +E + +   K  K  + E  KL   I+ + KDL D    KE + ++ +    
Sbjct: 820  ENEELSKQNEEMKEKLSKQDKEFEEEKEKLNAKIEKIEKDLSDGNNEKETLTNDFEDEVK 879

Query: 437  XXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTN----TEDV-----NEIAKVQEQLKQ 487
                    K+  I QL+ E  Q  E  + + +        +DV     N+I K  E L  
Sbjct: 880  RIEEDIDNKNKQIKQLEEEKSQLNEEMNKLQLNNEFLQKQKDVVETENNKIKKDFESLLS 939

Query: 488  ELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNF 547
             LN   K   +K   E+ +   E+      E++     M   K    + L++++    N 
Sbjct: 940  SLNKPDKSEMIKKFDEEKQQELEKTKTAKSELENQIHQMSIEKQKLTINLEKLENDKLNL 999

Query: 548  SK-VSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEME 606
               V+D   +   +T+ L  L +K  +L+    +L ++  +  + R  E  +  K  E++
Sbjct: 1000 QNIVNDYQSKNSEMTKNLQDLQKKNFDLQNLYDDL-INKTNEQNHRN-EKSLENKDEEIK 1057

Query: 607  NLAETRLKAISLLESQKFDLV---QELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVH 663
             L +T+ +  S +ESQ   L    +++ +L+ K +++E++  + + +  +++ SE++  H
Sbjct: 1058 QLKDTQHELESKIESQLESLQNNEEKIKLLESKIEDLEEEKLEQNNINQNKI-SELE--H 1114

Query: 664  LEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDK 723
              E++   S +  E    I  L+   ++   TI+ L    E++  + +N         D 
Sbjct: 1115 KIEELQNNSLNNDENENKISELENQVQEYQETIEKLRKQIEELEKEKENK-------ADT 1167

Query: 724  LEKMSAEKISELLAKINHEEQSKIQTQFGIDAK-IQERDLYIENIESELSKYKSRICRLE 782
             E  S+ KI EL  KI  EE  K    F  + + I +    +  + +E+S  +   C+LE
Sbjct: 1168 SETESSTKIKELEDKI--EELEKENDLFQNEGESILDLQEEVTKLNNEISTLRQLTCKLE 1225

Query: 783  ESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLL 842
            E    ++D     E+    L   L+EK+K          ++   L+VL   +  +++++ 
Sbjct: 1226 EDNKTLKDGSEEDEKLISSLRKQLKEKEKEKESENDNISQIKTNLSVLSKENDKLKREMQ 1285

Query: 843  EIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRD 902
              + +  +L      L  EN++L+  L D+++    +++K + T                
Sbjct: 1286 MKDDKISDLSILTSSLRTENEHLKSDL-DIKKKEIDIIKKNDET---------------- 1328

Query: 903  LESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEA 962
            ++S L +I + + +      K I+ L+ + +         +K L +  +++ E + QL+ 
Sbjct: 1329 VQSALDQIKNSNSS-----DKTIKSLQSQLSVCCMQKETLEKELEDMRKEDQETIAQLKQ 1383

Query: 963  QLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKD 1022
             + E +  I +L+    E N+M ++L  K  Q+Q  +     ++  N++N +    K   
Sbjct: 1384 VVNELQTKI-SLSSPQREFNQMKIQL--KQKQEQIERLRQENDELQNKVNYIKEKAKNDI 1440

Query: 1023 EEIIALNQ--KINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLD---SKQH 1077
            ++II   Q  ++ +++ + +S VSD   K+  F  + + + E+   + KQL      +Q 
Sbjct: 1441 KDIIKKTQVPEVKSSEKT-LSEVSDLRRKVLMFDKENQKLTEQNNELKKQLQSISVLEQR 1499

Query: 1078 NEELQILVREQDDQIKEL-KETKLTFEMNIPKTE-GMIISSTIEPMSDDANNVDXXXXXX 1135
             +E    + +   + KEL +E KL  +    KT+       T+   S  ++ +       
Sbjct: 1500 EKEYITQISKLTKKTKELEEENKLIKKSEEDKTDIEQRYLDTVTNTSKMSHEIQTLNETI 1559

Query: 1136 XXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQ 1195
                  L  Q +++ +QE+  +Q + + L T L     ++ +    N +L      N  +
Sbjct: 1560 NTLTQKLS-QLKKQHLQEKKEMQIEVSTLKTSLDSSLKELEEERKHNMQLIKDSKTNIVK 1618

Query: 1196 INQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAE 1237
            +++L+    +L  +N+  +S+V+ LR+S  S + Q    I++
Sbjct: 1619 LSELERTHAELRNQNET-ISSVSVLRTSPVSPLRQESSIISD 1659



 Score =  135 bits (327), Expect = 8e-30
 Identities = 207/1039 (19%), Positives = 441/1039 (42%), Gaps = 82/1039 (7%)

Query: 575  EEEKGNLQLHLVDY-DSGRMIESDVYKKMIE---MENLAETRL-KAISLLESQKFDLVQE 629
            E+ +G+++ HL+    +  ++  D   K+IE   +  + E ++  A++ ++S  ++L  E
Sbjct: 429  EQTRGDVK-HLISLLFTSLLMYKDCEDKIIENICLLLIGEEKVYNALTEMKSNSYELWNE 487

Query: 630  LHILQQKYDEVEDKLADISQ---LQSDQVCSEIKSVH--LEEQIDALSASKKELALVIEN 684
                  K    +  L ++SQ   L  ++V  E+K ++  L+E+   +  ++K     + +
Sbjct: 488  FEEDLIKIIMDKKPLENVSQFDNLTDEEVKKELKKLNDDLKEKDKIIEENEKNNEQKVSD 547

Query: 685  LKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQ 744
            LK   E L    K  EN+  D++ KL N  +EN  L ++ E+  +E + +L  +  + + 
Sbjct: 548  LKKQIEDLS---KQKENENSDVLQKLDNLQKENQKLKEENEEKESE-LQKLKQENENLKN 603

Query: 745  SKIQTQFGIDAKIQERDLYIENI--ESELSKYKSRIC---RLEESIAVMEDRRYSLERKA 799
               Q     D K+ E    IE++  E+EL + +       ++ E   ++ED +   E+  
Sbjct: 604  IDAQKVTYDDEKVSELQKIIEDLKKENELIQNQKETNDNEKISELQKIVEDLKNENEKLK 663

Query: 800  DQLGSYLQEKQKAYSEYTIQEDELVNRLAVL-MDHDRVVEKQLLEIEHENKELQKKNQIL 858
             ++   + + QKA  E     ++L+ +L    ++ +   +K++ E+  + ++LQ +   L
Sbjct: 664  SEVNQKVTDLQKAEGE-----NDLIKKLQEENLEIENEKDKEISELNEKLEKLQNQVNNL 718

Query: 859  LEENQNLQISLSDMQQHYNALVEKA-NRTDLAESESTKYQTQLRDLESNLKRITHEHQTL 917
              E       +S +Q   N L E+  +R D  + E    + ++  LE+    +       
Sbjct: 719  SSEKVTKDDIISSLQSEVNDLQEEIESRKDDKQKEINSLKEKIETLENEKISLQDSMNEE 778

Query: 918  IVQKKKEIEDLEIE---FNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENL 974
            I + ++EI +L+ E     T+ E   +  + L EK + + E   +L  Q +E K  +   
Sbjct: 779  IHKLEEEISNLQNEKSVLETENEKLSKQIEELQEKEKSSQEENEELSKQNEEMKEKLSKQ 838

Query: 975  NMNVEE-LNKMN--LELIDKHVQKQQTQSPDYTEQYINEINKL-------NALLKQKDEE 1024
            +   EE   K+N  +E I+K +     +    T  + +E+ ++       N  +KQ +EE
Sbjct: 839  DKEFEEEKEKLNAKIEKIEKDLSDGNNEKETLTNDFEDEVKRIEEDIDNKNKQIKQLEEE 898

Query: 1025 IIALNQKINNAQVS------YMSMVSDYESKLAQ-FTTKLE--NMEEEMQRVSKQLLDSK 1075
               LN+++N  Q++         +V    +K+ + F + L   N  ++ + + K   + +
Sbjct: 899  KSQLNEEMNKLQLNNEFLQKQKDVVETENNKIKKDFESLLSSLNKPDKSEMIKKFDEEKQ 958

Query: 1076 QHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXX 1135
            Q  E+ +    E ++QI ++   K    +N+ K E   ++         + N +      
Sbjct: 959  QELEKTKTAKSELENQIHQMSIEKQKLTINLEKLENDKLNLQNIVNDYQSKNSEMTKNLQ 1018

Query: 1136 XXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVV---- 1191
                    +Q   + +  ++   EQ+ +    L+    +I QL+    EL          
Sbjct: 1019 DLQKKNFDLQNLYDDLINKT--NEQNHRNEKSLENKDEEIKQLKDTQHELESKIESQLES 1076

Query: 1192 ---NQEQINQLKSKLEQLNTE----NDNLLSTVAELRSSISSAVDQR-GFEIAELWKQHL 1243
               N+E+I  L+SK+E L  E    N+   + ++EL   I    +     +  E     L
Sbjct: 1077 LQNNEEKIKLLESKIEDLEEEKLEQNNINQNKISELEHKIEELQNNSLNNDENENKISEL 1136

Query: 1244 AQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKL-QDK 1302
              +  ++Q+T  +LR Q+   E + E   D+ ++ +  +  ++    +    +N L Q++
Sbjct: 1137 ENQVQEYQETIEKLRKQIEELEKEKENKADTSETESSTKIKELEDKIEELEKENDLFQNE 1196

Query: 1303 EEHLRNLQEKYADVINQIEILRS---EIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSY 1359
             E + +LQE+   + N+I  LR    ++E++                     L+ E +  
Sbjct: 1197 GESILDLQEEVTKLNNEISTLRQLTCKLEEDNKTLKDGSEEDEKLISSLRKQLK-EKEKE 1255

Query: 1360 KQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQK 1419
            K+ +  +I  I    + L K +            +++D       L  + E   S++  K
Sbjct: 1256 KESENDNISQIKTNLSVLSKENDKLKREMQMKDDKISDLSILTSSLRTENEHLKSDLDIK 1315

Query: 1420 THEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKE 1479
              E  I + ++NDE        ++     +      +S+L++  ++        E M+KE
Sbjct: 1316 KKE--IDIIKKNDETVQSALDQIKNSNSSDKTIKSLQSQLSVCCMQKETLEKELEDMRKE 1373

Query: 1480 SEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDE 1539
             + E +  ++++  ++   +SL+    E N           +M+  L+ ++ +I  L  E
Sbjct: 1374 DQ-ETIAQLKQVVNELQTKISLSSPQREFN-----------QMKIQLKQKQEQIERLRQE 1421

Query: 1540 ITNLQNMVRASSSKIQKHV 1558
               LQN V     K +  +
Sbjct: 1422 NDELQNKVNYIKEKAKNDI 1440



 Score =  126 bits (303), Expect = 7e-27
 Identities = 176/802 (21%), Positives = 361/802 (45%), Gaps = 84/802 (10%)

Query: 795  LERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAV-LMDHDRVVEKQLLEIEHENKELQK 853
            ++++  +L   L+EK K   E     ++ V+ L   + D  +  E +  ++  +   LQK
Sbjct: 516  VKKELKKLNDDLKEKDKIIEENEKNNEQKVSDLKKQIEDLSKQKENENSDVLQKLDNLQK 575

Query: 854  KNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHE 913
            +NQ L EEN+  +  L  ++Q      E  N  ++   + T    ++ +L+  ++ +  E
Sbjct: 576  ENQKLKEENEEKESELQKLKQ------ENENLKNIDAQKVTYDDEKVSELQKIIEDLKKE 629

Query: 914  HQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNI-EYVTQLEAQLQEYKNNIE 972
            ++  ++Q +KE  D E    ++++  + D K  NEK +  + + VT L  Q  E +N++ 
Sbjct: 630  NE--LIQNQKETNDNEKI--SELQKIVEDLKNENEKLKSEVNQKVTDL--QKAEGENDL- 682

Query: 973  NLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKI 1032
                 +++L + NLE I+    K+ ++  +  E+  N++N L++    KD+ I +L  ++
Sbjct: 683  -----IKKLQEENLE-IENEKDKEISELNEKLEKLQNQVNNLSSEKVTKDDIISSLQSEV 736

Query: 1033 NNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQI 1092
            N+ Q    S   D + ++     K+E +E E  ++S Q  DS   NEE+  L    +++I
Sbjct: 737  NDLQEEIESRKDDKQKEINSLKEKIETLENE--KISLQ--DSM--NEEIHKL----EEEI 786

Query: 1093 KELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQ 1152
              L+  K   E     TE   +S  IE + +   +                 +E EE  +
Sbjct: 787  SNLQNEKSVLE-----TENEKLSKQIEELQEKEKSSQ---------------EENEELSK 826

Query: 1153 ERSVLQEQSAKLNTELQECYTKI-IQLETLNTELTGHDVVNQEQINQLKSKLEQLNTEND 1211
            +   ++E+ +K + E +E   K+  ++E +  +L+  +   +   N  + +++++  + D
Sbjct: 827  QNEEMKEKLSKQDKEFEEEKEKLNAKIEKIEKDLSDGNNEKETLTNDFEDEVKRIEEDID 886

Query: 1212 NLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQL 1271
            N    + +L    S   ++      +L  + L Q++ D  +TE+      +  +  +E L
Sbjct: 887  NKNKQIKQLEEEKSQLNEE--MNKLQLNNEFL-QKQKDVVETEN------NKIKKDFESL 937

Query: 1272 LDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEK 1331
            L S+    + E  K    E+   L+     K E L N   + +    ++ I   ++E++K
Sbjct: 938  LSSLNKPDKSEMIKKFDEEKQQELEKTKTAKSE-LENQIHQMSIEKQKLTINLEKLENDK 996

Query: 1332 VAFXXXXXXXXXXXXXXXX---DLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXX 1388
            +                     DL+ +N   + + +  I   NE+N + +KS        
Sbjct: 997  LNLQNIVNDYQSKNSEMTKNLQDLQKKNFDLQNLYDDLINKTNEQNHRNEKSLENKDEEI 1056

Query: 1389 XXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTIT-LTQRNDEFENVRQQLV-EYEK 1446
                   ++ E+K+      L+  + +I  K  E  I  L +   E  N+ Q  + E E 
Sbjct: 1057 KQLKDTQHELESKIESQLESLQNNEEKI--KLLESKIEDLEEEKLEQNNINQNKISELEH 1114

Query: 1447 RIEDLTYEK----ESELAILRLKMHENANHYETMQK-ESEIERVKLIEELNVKITESVSL 1501
            +IE+L        E+E  I  L+ ++   + ET++K   +IE ++  +E     +E+ S 
Sbjct: 1115 KIEELQNNSLNNDENENKISELE-NQVQEYQETIEKLRKQIEELEKEKENKADTSETESS 1173

Query: 1502 NKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMV---RASSSKIQKHV 1558
             K + EL   +EE + K N++    +N+   I+ L +E+T L N +   R  + K+++  
Sbjct: 1174 TK-IKELEDKIEE-LEKENDL---FQNEGESILDLQEEVTKLNNEISTLRQLTCKLEEDN 1228

Query: 1559 SFASDTKQGRDEQLDNTMNKEL 1580
                D  +  DE+L +++ K+L
Sbjct: 1229 KTLKDGSE-EDEKLISSLRKQL 1249



 Score = 66.1 bits (154), Expect = 8e-09
 Identities = 86/430 (20%), Positives = 182/430 (42%), Gaps = 19/430 (4%)

Query: 1169 QECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAV 1228
            ++ Y  + ++++ + EL      +  +I   K  LE ++ + DNL  T  E++  +    
Sbjct: 468  EKVYNALTEMKSNSYELWNEFEEDLIKIIMDKKPLENVS-QFDNL--TDEEVKKELKKLN 524

Query: 1229 D--QRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKI 1286
            D  +   +I E  +++  Q+ +D +K   +L  Q     S   Q LD++Q   Q+   + 
Sbjct: 525  DDLKEKDKIIEENEKNNEQKVSDLKKQIEDLSKQKENENSDVLQKLDNLQKENQKLKEE- 583

Query: 1287 VTMEQVTSLQNKLQDKEEHLRNLQ-EKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXX 1345
               E+ + LQ KL+ + E+L+N+  +K      ++  L+  IED K              
Sbjct: 584  -NEEKESELQ-KLKQENENLKNIDAQKVTYDDEKVSELQKIIEDLKKENELIQNQKETND 641

Query: 1346 XXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRV---NDAEAKV 1402
                 +L+   +  K   E+    +N++   L+K+              +   N+ + ++
Sbjct: 642  NEKISELQKIVEDLKNENEKLKSEVNQKVTDLQKAEGENDLIKKLQEENLEIENEKDKEI 701

Query: 1403 LELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAIL 1462
             EL  +LE   +++   + E  +T   ++D   +++ ++ + ++ IE    +K+ E+  L
Sbjct: 702  SELNEKLEKLQNQVNNLSSE-KVT---KDDIISSLQSEVNDLQEEIESRKDDKQKEINSL 757

Query: 1463 RLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEM 1522
            + K+    N   ++Q     E  KL EE++    E   L  +  +L+K +EE   K    
Sbjct: 758  KEKIETLENEKISLQDSMNEEIHKLEEEISNLQNEKSVLETENEKLSKQIEELQEKEKSS 817

Query: 1523 QTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHV-SFASDTKQGRDEQLDNTMNKELL 1581
            Q   E    +   + ++++           K+   +     D   G +E+   T+  +  
Sbjct: 818  QEENEELSKQNEEMKEKLSKQDKEFEEEKEKLNAKIEKIEKDLSDGNNEK--ETLTNDFE 875

Query: 1582 DAVPRAELDL 1591
            D V R E D+
Sbjct: 876  DEVKRIEEDI 885


>UniRef50_A0BUU6 Cluster: Chromosome undetermined scaffold_13, whole
            genome shotgun sequence; n=1; Paramecium tetraurelia|Rep:
            Chromosome undetermined scaffold_13, whole genome shotgun
            sequence - Paramecium tetraurelia
          Length = 1010

 Score =  144 bits (349), Expect = 2e-32
 Identities = 207/1009 (20%), Positives = 438/1009 (43%), Gaps = 80/1009 (7%)

Query: 510  EQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQ 569
            ++I QL   I   N    + +SN K  ++  ++ +D    V D+N+ ++   + L   S 
Sbjct: 12   KKIAQLTKVIFFLNTKNDEYESNLKAVVQAYEQEMDQI--VKDANQIVLTYKQALDKQS- 68

Query: 570  KVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEM--ENLAETRLKAISLLESQKFDLV 627
            K  ++++E   LQ  +        IE   Y+K +E   + L     K I  ++ +     
Sbjct: 69   KNDDIQQELKQLQEKVQVEKQTAQIEYSQYRKRMEEKEQGLVTQYEKKIKDIQKETEFQK 128

Query: 628  QELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKEL--ALVIENL 685
            Q+   L ++ D+V  K  ++ +    Q+   IK    +E+ D L   K E    +  ++ 
Sbjct: 129  QKFDDLSKQVDKVIMKQEELRRGSQKQLEDTIKE--WKEKYDTLMRKKLEQDDQIAEKDR 186

Query: 686  KLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQS 745
            +L K+QL         + +D++ K++   +++ +  D+L+ +  +   + L  + +E  S
Sbjct: 187  RLQKQQL---------EIDDLLKKIEEEKRKSKEAQDRLQDLMKQNFDQKLQSLQNEINS 237

Query: 746  KIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIA-----VMEDRRYSLERKAD 800
              Q    +  +  +   +  N+  E+++ K +I +L   +        + +   L +K +
Sbjct: 238  LKQEVTNLKNQKDDLTKHNHNLSDEVNQLKDQIAKLTLDLKDIGQKYQQSQTEVLSQKNE 297

Query: 801  -----QLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKN 855
                 Q  S L++K K  +    Q + L ++L        + E QL + +  + E Q K+
Sbjct: 298  NSKLKQTNSDLEDKIKQLNS---QIENLKSQLHAYQQDGSMRETQLTK-QLSDLEQQLKS 353

Query: 856  QILLEENQNLQISLSDMQQHYNALVEKANRT-DLAESESTKYQTQLRDLESNLKRITHEH 914
            +    E + L I L+++Q+  + L  + N   D ++  ++    ++ +L+ N++R+  E 
Sbjct: 354  KDF--EIRELHIKLNELQKKADMLQMELNAVRDASDRSNSDKLKEIEELKKNVRRLEDEI 411

Query: 915  QTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYV-TQLEAQLQEYKNNIEN 973
            + L  Q K ++ +LE     +IE    +K+ L ++YE+ I+ + T+ E +L+E +  +EN
Sbjct: 412  EKLQNQAKNQMGELEKNLLNKIEQIEAEKRELIKRYEEKIQKITTEYELKLKELREELEN 471

Query: 974  LNMNVEELNKMNLELID-------KHVQKQQTQSPDYTEQYINE-INKLNALLKQKDEEI 1025
               N+E  +   +E I        K +++Q        E+   + IN L   + Q + +I
Sbjct: 472  KIKNLENNHAQEIESIKNDFNKRLKQLEQQLNDERANVEKSAGQAINDLKNQINQANLKI 531

Query: 1026 IALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVS------KQLLDSKQHNE 1079
              L  +I N Q     +       L Q T+K + +++ +QR++      KQ+      N+
Sbjct: 532  SGLESEIQNLQNKIKELEQTIIYNLNQITSKEQEIKQLLQRIAELEDKIKQIQSEGSSNQ 591

Query: 1080 -ELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXX 1138
             +LQ  ++E + QIK+ +   L  +      + +     I+ +                 
Sbjct: 592  GQLQTRIQELEQQIKQQRIDLLREKDEQLNQQKLSYEQQIDSLRQQYEAEKKQIKVDFER 651

Query: 1139 XXXLKVQEEEEFIQERSVLQE----------QSAKLNTELQECYTKIIQLETLNTELTGH 1188
               LK +E  + +Q+ + L++          +  KL  E  E   K I L+  N E+   
Sbjct: 652  KLQLKEEEIAKLLQQITSLKKDMETGQGDWARRLKLKEEEFEQMLKEINLKH-NYEIELL 710

Query: 1189 DVVNQEQINQLKSKLE-QLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQRE 1247
            D  N +   Q+K   E ++    D+L     E ++ ++    +   +   L K +  Q +
Sbjct: 711  DKKNTQMKEQMKVYYEKEIQQIKDDL---NVETQNKLNQQAREFENQKQSLIKNYENQLQ 767

Query: 1248 ADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLR 1307
               Q+ E +L  ++S FE+K +QL + ++   QE+++   T + ++ L+ +L++  E  +
Sbjct: 768  DVQQRYERQLNDKISEFENKLKQLQNKLE---QEQSDHKATKDIISDLRRQLENSLELNK 824

Query: 1308 NLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSI 1367
            N  +KY     QI+IL+ +I+D  + +                 ++   +  KQ+++Q  
Sbjct: 825  NTSDKYE---QQIKILQQQIKDLNIKYQQAEVEFSKQIKEKDVWVQQMKEEAKQLEQQLR 881

Query: 1368 LNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITL 1427
             ++N+   QLK S                 A+  +++    LE    EI +   E     
Sbjct: 882  QSLNQ---QLKDSLIKQKDFADNLKNEFEQAQQLLMQKLQMLEEDYKEITRLYEE----R 934

Query: 1428 TQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETM 1476
              R ++ E ++Q   +   + E++    E ++   +L++    N+Y  M
Sbjct: 935  PSRPEDLELIKQLQSQVNLKDEEIKKVNE-QMKYFKLELINRDNNYNKM 982



 Score = 93.1 bits (221), Expect = 6e-17
 Identities = 183/918 (19%), Positives = 394/918 (42%), Gaps = 92/918 (10%)

Query: 169  ETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAM 228
            E  I D+Q++   + Q  +  +K                    EDT ++  +  +  +  
Sbjct: 114  EKKIKDIQKETEFQKQKFDDLSKQVDKVIMKQEELRRGSQKQLEDTIKEWKEKYDTLMRK 173

Query: 229  EAEWKD---EKQRLLK--DIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXX 283
            + E  D   EK R L+   +E  D+     EE  K  EA      L      Q+L+    
Sbjct: 174  KLEQDDQIAEKDRRLQKQQLEIDDLLKKIEEEKRKSKEAQDRLQDLMKQNFDQKLQSLQN 233

Query: 284  XXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSL--EIANMTELTKKI---------ELL- 331
                       L  Q  + +       +E   L  +IA +T   K I         E+L 
Sbjct: 234  EINSLKQEVTNLKNQKDDLTKHNHNLSDEVNQLKDQIAKLTLDLKDIGQKYQQSQTEVLS 293

Query: 332  -EHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLS 390
             ++ N +++QTN +LE+K+  + ++ + + S          ++ G    +++    S L 
Sbjct: 294  QKNENSKLKQTNSDLEDKIKQLNSQIENLKSQLH-----AYQQDGSMRETQLTKQLSDLE 348

Query: 391  SETLNQDTDKK---INKNEI-AKLEMVIQSLN--KDLVDKEYVISEKDTXXXXXXXXXXG 444
             +  ++D + +   I  NE+  K +M+   LN  +D  D+      K+            
Sbjct: 349  QQLKSKDFEIRELHIKLNELQKKADMLQMELNAVRDASDRSNSDKLKEIEELKKNVRRLE 408

Query: 445  KDTLIAQLQLEHQQ-HMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIE 503
             +    Q Q ++Q   +E   L  +     +  E+ K  E+  Q++  E  ++ +K+L E
Sbjct: 409  DEIEKLQNQAKNQMGELEKNLLNKIEQIEAEKRELIKRYEEKIQKITTEY-ELKLKELRE 467

Query: 504  KLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEE 563
            +L   E +I  L +   A     IK   N +LK  + Q   +  +    + + I  L  +
Sbjct: 468  EL---ENKIKNLENN-HAQEIESIKNDFNKRLKQLEQQLNDERANVEKSAGQAINDLKNQ 523

Query: 564  LHHLSQKVAELEEEKGNLQLHL------VDYDSGRMIESDVYKKMIEMENLAETRLKAIS 617
            ++  + K++ LE E  NLQ  +      + Y+  ++   +   K + ++ +AE   K I 
Sbjct: 524  INQANLKISGLESEIQNLQNKIKELEQTIIYNLNQITSKEQEIKQL-LQRIAELEDK-IK 581

Query: 618  LLESQKFDLVQELHI-LQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDAL----S 672
             ++S+      +L   +Q+   +++ +  D+ + + +Q+  +   +  E+QID+L     
Sbjct: 582  QIQSEGSSNQGQLQTRIQELEQQIKQQRIDLLREKDEQLNQQ--KLSYEQQIDSLRQQYE 639

Query: 673  ASKKELALVIE-NLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEK 731
            A KK++ +  E  L+L +E++   ++ + + K+D M   Q       D   +L K+  E+
Sbjct: 640  AEKKQIKVDFERKLQLKEEEIAKLLQQITSLKKD-METGQG------DWARRL-KLKEEE 691

Query: 732  ISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDR 791
              ++L +IN +   +I+    +D K  +        E     Y+  I ++++ + V    
Sbjct: 692  FEQMLKEINLKHNYEIEL---LDKKNTQMK------EQMKVYYEKEIQQIKDDLNVETQN 742

Query: 792  RYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKEL 851
            + +      Q   +  +KQ     Y  Q  ++  R      ++R +  ++ E E++ K+L
Sbjct: 743  KLN-----QQAREFENQKQSLIKNYENQLQDVQQR------YERQLNDKISEFENKLKQL 791

Query: 852  QKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRIT 911
            Q K    LE+ Q+   +  D+       +E  N  +L ++ S KY+ Q++ L+  +K + 
Sbjct: 792  QNK----LEQEQSDHKATKDIISDLRRQLE--NSLELNKNTSDKYEQQIKILQQQIKDLN 845

Query: 912  HEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNI 971
             ++Q   V+  K+I++ ++      E A + ++ L +   + ++    L  Q +++ +N+
Sbjct: 846  IKYQQAEVEFSKQIKEKDVWVQQMKEEAKQLEQQLRQSLNQQLK--DSLIKQ-KDFADNL 902

Query: 972  ENLNMNVEELNKMNLELID---KHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIAL 1028
            +N     ++L    L++++   K + +   + P   E  +  I +L + +  KDEEI  +
Sbjct: 903  KNEFEQAQQLLMQKLQMLEEDYKEITRLYEERPSRPED-LELIKQLQSQVNLKDEEIKKV 961

Query: 1029 NQKINNAQVSYMSMVSDY 1046
            N+++   ++  ++  ++Y
Sbjct: 962  NEQMKYFKLELINRDNNY 979



 Score = 58.0 bits (134), Expect = 2e-06
 Identities = 88/460 (19%), Positives = 188/460 (40%), Gaps = 31/460 (6%)

Query: 1142 LKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKS 1201
            L  + +E     ++V+Q    +++  +++    ++  +    + + +D + QE    LK 
Sbjct: 24   LNTKNDEYESNLKAVVQAYEQEMDQIVKDANQIVLTYKQALDKQSKNDDIQQE----LKQ 79

Query: 1202 KLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHE-LRVQ 1260
              E++  E        ++ R  +     ++G       K    Q+E +FQK + + L  Q
Sbjct: 80   LQEKVQVEKQTAQIEYSQYRKRMEEK--EQGLVTQYEKKIKDIQKETEFQKQKFDDLSKQ 137

Query: 1261 LSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQI 1320
            +     K E+L    Q   ++   +    E+  +L  K  ++++ +     +      +I
Sbjct: 138  VDKVIMKQEELRRGSQKQLEDTIKE--WKEKYDTLMRKKLEQDDQIAEKDRRLQKQQLEI 195

Query: 1321 EILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILN-INEENAQLKK 1379
            + L  +IE+EK                   DL  +N   K    Q+ +N + +E   LK 
Sbjct: 196  DDLLKKIEEEK--------RKSKEAQDRLQDLMKQNFDQKLQSLQNEINSLKQEVTNLKN 247

Query: 1380 SSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKD-SEIYQKTHEYTITLTQRNDEFENVR 1438
                           VN  + ++ +LT  L+LKD  + YQ++   T  L+Q+N+    ++
Sbjct: 248  QKDDLTKHNHNLSDEVNQLKDQIAKLT--LDLKDIGQKYQQSQ--TEVLSQKNEN-SKLK 302

Query: 1439 QQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKE-SEIER-VKL----IEELN 1492
            Q   + E +I+ L  + E+  + L     + +     + K+ S++E+ +K     I EL+
Sbjct: 303  QTNSDLEDKIKQLNSQIENLKSQLHAYQQDGSMRETQLTKQLSDLEQQLKSKDFEIRELH 362

Query: 1493 VKITE-SVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASS 1551
            +K+ E     +    ELN   +      ++    +E  +  +  L DEI  LQN  +   
Sbjct: 363  IKLNELQKKADMLQMELNAVRDASDRSNSDKLKEIEELKKNVRRLEDEIEKLQNQAKNQM 422

Query: 1552 SKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDL 1591
             +++K++    +  +    +L     +++       EL L
Sbjct: 423  GELEKNLLNKIEQIEAEKRELIKRYEEKIQKITTEYELKL 462


>UniRef50_UPI0000499259 Cluster: hypothetical protein 388.t00006; n=1;
            Entamoeba histolytica HM-1:IMSS|Rep: hypothetical protein
            388.t00006 - Entamoeba histolytica HM-1:IMSS
          Length = 1598

 Score =  144 bits (348), Expect = 2e-32
 Identities = 227/1080 (21%), Positives = 488/1080 (45%), Gaps = 108/1080 (10%)

Query: 457  QQHMEGPSLIHVGTNTEDVNEIAKVQEQL-KQELNDEIKDVNVKDLIEKLKSAEEQITQL 515
            QQ+   P +  +G++   + +  K Q  L K    DE+ +   K+ +EKLK A+E++++L
Sbjct: 300  QQNQTIPIIDSIGSSR--IKKTQKEQRGLNKINSFDEVVEKKRKEDLEKLKKAKEELSKL 357

Query: 516  NDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELE 575
             +E  AA K   K ++N K++  +         ++ +   EI +L  E    S ++ + +
Sbjct: 358  EEEKIAAEKE--KEEANEKVQKLE--------EEMREKKIEIEKLKVEREE-SFRLLKGQ 406

Query: 576  EEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQ 635
            +E+   ++  V+ +  + I+ +V K     E   E  LK I  LE+   +L  E +    
Sbjct: 407  KEQSLCEIQRVEQEKEKRIKEEVEKAHQLREKEFEELLKRIKELEA--INLENEYN---- 460

Query: 636  KYDEVEDKLADISQLQSDQ-----VCSEIKSVHLE--EQIDALSASKKELALVIENLKLD 688
              DE++ K  +IS +Q ++     +  EIK  + +  ++I+ L   K+E A + E +K +
Sbjct: 461  -KDELKKKCLEISNIQEEKEELILIVQEIKEENEKRIKEIENLQEKKEENARIFEEMKKE 519

Query: 689  KEQLYGTI-------KDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINH 741
             E+    +        +L+N+ + I NK  N +++   LT+++E +  E  ++       
Sbjct: 520  IEEREKELIIERKQEIELQNEVQRITNKSNNNVEK---LTNQIEVLQKEINNQRSLLQEI 576

Query: 742  EEQSKIQTQFGIDAKIQE---RDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERK 798
            EE++K+      +AKI+E   ++ + E +     K +    R+ +   +M++    L ++
Sbjct: 577  EEKNKLFNNEIKEAKIKEEQTKEFFTEEMNQITKKGEEERNRIMKENVIMKEEIKKLNKE 636

Query: 799  ADQLGSYLQEKQ------KAYSEYTIQE-DELVNRLAVLMDHDRVVEKQLLEIEHENKEL 851
             +++     +K+      K   +  IQ+ +E+ N    L +    ++K + E+E  NK  
Sbjct: 637  KEEMNEKYNKKEIENEDDKEKLKNEIQKREEIENNKISLQNQIFQLKKIIEELEEGNKYN 696

Query: 852  QKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESES--TKYQTQLRDLESNLKR 909
              K  IL EE     I +  +++ +   ++      + E E    K + +++  E N K 
Sbjct: 697  TNKINILTEECSKKDIEIEKIKKEFEQEIKNEREEQIKEKEDEIIKIKEEMKMAEENYKN 756

Query: 910  ----ITHEHQTLIVQKKKEIEDLEIEFNTQI-ESAIRDKKVLNEKYEKNI--EYVTQLEA 962
                I  +    I Q K+E ++ E E +    +  I  K+++ +K E  I  E + +   
Sbjct: 757  NISTIRTKKDLEIHQLKEEEQNKEKEIDILTNQKEIISKELITKKEENEILKEKINETLK 816

Query: 963  QL---QEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKL-NALL 1018
            +L   +E  N  + +N  ++E  K     I K  +++ T      E+  N  NK+ N   
Sbjct: 817  ELKEKEESNNQYQQINEEMKEKLKEKENEI-KIKEEKITNKEKEMEELKNNFNKVENENE 875

Query: 1019 KQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHN 1078
            K+  E+I  LN++I   + S +  + + E   A     L+N  EE++ + ++++ SK + 
Sbjct: 876  KRFKEKINELNKEIEEQKKS-IKNIKEEEYLFADII--LDN--EEIKELKEEMIHSKLNR 930

Query: 1079 EELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXX 1138
            + ++++ +++ +Q+   K+     ++ I  ++  I +  I+  +D+   ++         
Sbjct: 931  KMIELIKKKEMEQLINDKK-----DLEIQLSKHQIENQKIQNQNDELKKINQTKENEKVL 985

Query: 1139 XXXL--KVQEEEEFIQERSVLQE-QSAKLNTELQECYTKIIQLETLNTELTGHDVVN-QE 1194
               +  K+Q +   ++E+  +QE ++ KL +E+   Y+K I   T   EL   +    + 
Sbjct: 986  LNEINEKLQNKINELKEKDKIQEDENNKLQSEITN-YSKTITSLTEKIELCKTENTKIEN 1044

Query: 1195 QINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTE 1254
            +I Q ++++E++  E +  L    EL   I   +  + FE  ++ +Q + Q        E
Sbjct: 1045 KIQQKENEIEEIKKEKEIALE---ELNHEIKKKI--KDFE-NQIKEQEIIQNNQIITIKE 1098

Query: 1255 HELRV-QLSAFESKYEQLLDSVQ-SSTQEETNKIVTM-EQVTSLQNKLQDKEEHLRNLQE 1311
             +  + +L     K +++++       +EE NKI+ + E+   L+NK ++  + +  L++
Sbjct: 1099 KDQNIYELKQHIEKMKKIIEETPLKEYEEENNKILKLKEENELLENKNKENIQKIEVLKK 1158

Query: 1312 KYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNIN 1371
            K  ++ N++++    IE EK+                  + + E +  K   +Q  + + 
Sbjct: 1159 KEEELNNKMQL----IEQEKINLNKEINIEIQKLKEELENEKNEKEKMKDFIKQKEIELQ 1214

Query: 1372 EENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRN 1431
            +E  + +               ++ D + K+       ++ +  + QK  E        +
Sbjct: 1215 KEKDEKE----------CIIQQKIRDEKEKINAQESVRKMAEKIVQQKIEENQKKNILES 1264

Query: 1432 DEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQK--ESEIERVKLIE 1489
             E E   ++ +E EK I     EK+ E  I+   ++      E ++K  + +IE +KLIE
Sbjct: 1265 LEEEKRNRKKIENEKEI----IEKDKE--IMEKNINSLKEEIEELKKKDKKKIEDIKLIE 1318



 Score =  135 bits (327), Expect = 8e-30
 Identities = 199/1015 (19%), Positives = 440/1015 (43%), Gaps = 93/1015 (9%)

Query: 603  IEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSV 662
            I    + +T+ +   L +   FD V E    ++  ++++    ++S+L+ +++ +E +  
Sbjct: 311  IGSSRIKKTQKEQRGLNKINSFDEVVEKK-RKEDLEKLKKAKEELSKLEEEKIAAEKEKE 369

Query: 663  HLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQEN----M 718
               E++  L    +E  + IE LK+++E+ +  +K     KE  + ++Q   QE      
Sbjct: 370  EANEKVQKLEEEMREKKIEIEKLKVEREESFRLLK---GQKEQSLCEIQRVEQEKEKRIK 426

Query: 719  DLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRI 778
            +  +K  ++  ++  ELL +I   E   ++ ++  D +++++ L I NI+ E  +    +
Sbjct: 427  EEVEKAHQLREKEFEELLKRIKELEAINLENEYNKD-ELKKKCLEISNIQEEKEELILIV 485

Query: 779  CRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVE 838
              ++E          +L+ K ++     +E +K   E   +E EL+      ++    V+
Sbjct: 486  QEIKEENEKRIKEIENLQEKKEENARIFEEMKKEIEE---REKELIIERKQEIELQNEVQ 542

Query: 839  KQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQT 898
            +   +  +  ++L  + ++L +E  N +  L ++++       +     + E ++ ++ T
Sbjct: 543  RITNKSNNNVEKLTNQIEVLQKEINNQRSLLQEIEEKNKLFNNEIKEAKIKEEQTKEFFT 602

Query: 899  Q-----LRDLESNLKRITHEHQTL---IVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKY 950
            +      +  E    RI  E+  +   I +  KE E++  ++N +      DK+ L  + 
Sbjct: 603  EEMNQITKKGEEERNRIMKENVIMKEEIKKLNKEKEEMNEKYNKKEIENEDDKEKLKNEI 662

Query: 951  EKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMN---LELIDKHVQKQQTQSPDYTEQY 1007
            +K  E +   +  LQ     ++ +   +EE NK N   + ++ +   K+  +     +++
Sbjct: 663  QKR-EEIENNKISLQNQIFQLKKIIEELEEGNKYNTNKINILTEECSKKDIEIEKIKKEF 721

Query: 1008 INEI-NKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQR 1066
              EI N+    +K+K++EII + +++  A+ +Y + +S   +K      ++  ++EE Q 
Sbjct: 722  EQEIKNEREEQIKEKEDEIIKIKEEMKMAEENYKNNISTIRTKK---DLEIHQLKEEEQN 778

Query: 1067 VSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDAN 1126
              K          E+ IL  +++   KEL   K   E+   K     I+ T++ + +   
Sbjct: 779  KEK----------EIDILTNQKEIISKELITKKEENEILKEK-----INETLKELKEKEE 823

Query: 1127 NVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELT 1186
            + +            LK +E E  I+E  +  ++      E++E      ++E  N +  
Sbjct: 824  SNNQYQQINEEMKEKLKEKENEIKIKEEKITNKEK-----EMEELKNNFNKVENENEKRF 878

Query: 1187 GHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQR 1246
                  +E+IN+L  ++E+      N+          I   +D    EI EL K+ +   
Sbjct: 879  ------KEKINELNKEIEEQKKSIKNIKEEEYLFADII---LDNE--EIKEL-KEEMIHS 926

Query: 1247 EADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHL 1306
            + + +  E   + ++    +  + L +   S  Q E  KI          N+ ++ E+ L
Sbjct: 927  KLNRKMIELIKKKEMEQLINDKKDL-EIQLSKHQIENQKIQNQNDELKKINQTKENEKVL 985

Query: 1307 RN-LQEKYADVINQIEILRSEIEDE--KVAFXXXXXXXXXXXXXXXXDL-RTENQSYKQM 1362
             N + EK  + IN+++      EDE  K+                  +L +TEN   +  
Sbjct: 986  LNEINEKLQNKINELKEKDKIQEDENNKLQSEITNYSKTITSLTEKIELCKTENTKIENK 1045

Query: 1363 QEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHE 1422
             +Q    I E    +KK                ++ + K+ +  +Q+  K+ EI Q    
Sbjct: 1046 IQQKENEIEE----IKKEKEIALEELN------HEIKKKIKDFENQI--KEQEIIQNNQ- 1092

Query: 1423 YTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEI 1482
              IT+ +++     ++Q + + +K IE+   ++  E     LK+ E     E   KE+ I
Sbjct: 1093 -IITIKEKDQNIYELKQHIEKMKKIIEETPLKEYEEENNKILKLKEENELLENKNKEN-I 1150

Query: 1483 ERVKLI----EELNVKIT----ESVSLNKQV----AELNKALEEEVAKTNEMQTALENQE 1530
            ++++++    EELN K+     E ++LNK++     +L + LE E  +  +M+  ++ +E
Sbjct: 1151 QKIEVLKKKEEELNNKMQLIEQEKINLNKEINIEIQKLKEELENEKNEKEKMKDFIKQKE 1210

Query: 1531 IEIVTLNDE-ITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAV 1584
            IE+    DE    +Q  +R    KI    S     ++   ++++    K +L+++
Sbjct: 1211 IELQKEKDEKECIIQQKIRDEKEKINAQESVRKMAEKIVQQKIEENQKKNILESL 1265



 Score =  134 bits (325), Expect = 1e-29
 Identities = 214/999 (21%), Positives = 445/999 (44%), Gaps = 97/999 (9%)

Query: 233  KDEKQRLLKDIESKDVRISSLEEANKL---LEAARFEISLEHSKLAQELEQXXXXXXXXX 289
            K  K+ L K  E K       EEAN+    LE    E  +E  KL  E E+         
Sbjct: 348  KKAKEELSKLEEEKIAAEKEKEEANEKVQKLEEEMREKKIEIEKLKVEREESFRLLKGQK 407

Query: 290  XXXXXLAKQSIEPSCEE--KTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELEN 347
                    Q +E   E+  K E+E+   L      EL K+I+ LE +N +      EL+ 
Sbjct: 408  EQSL-CEIQRVEQEKEKRIKEEVEKAHQLREKEFEELLKRIKELEAINLENEYNKDELKK 466

Query: 348  KLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEI 407
            K   +    +      K+   LI ++       ++K        E  N    K+ N    
Sbjct: 467  KCLEISNIQE-----EKEELILIVQEIKEENEKRIK--------EIENLQEKKEENARIF 513

Query: 408  AKLEMVIQSLNKDL-VDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLI 466
             +++  I+   K+L ++++  I  ++             + L  Q+++  ++     SL+
Sbjct: 514  EEMKKEIEEREKELIIERKQEIELQNEVQRITNKSNNNVEKLTNQIEVLQKEINNQRSLL 573

Query: 467  HVGTNTEDV--NEI--AKV-QEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDA 521
                    +  NEI  AK+ +EQ K+   +E+  +  K   E+ +  +E +  + +EI  
Sbjct: 574  QEIEEKNKLFNNEIKEAKIKEEQTKEFFTEEMNQITKKGEEERNRIMKENVI-MKEEIKK 632

Query: 522  ANKNMIKVKSNHKLKLKQM------QKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELE 575
             NK   K + N K   K++      +K  +   K  +     + L  ++  L + + ELE
Sbjct: 633  LNKE--KEEMNEKYNKKEIENEDDKEKLKNEIQKREEIENNKISLQNQIFQLKKIIEELE 690

Query: 576  E-EKGNL-QLHLVDYD-SGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHI 632
            E  K N  +++++  + S + IE +  KK  E E +   R + I   E +   + +E+ +
Sbjct: 691  EGNKYNTNKINILTEECSKKDIEIEKIKKEFEQE-IKNEREEQIKEKEDEIIKIKEEMKM 749

Query: 633  LQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASK----KELALVIENLKLD 688
             ++ Y      +     L+  Q+  E    + E++ID L+  K    KEL    E  ++ 
Sbjct: 750  AEENYKNNISTIRTKKDLEIHQLKEE--EQNKEKEIDILTNQKEIISKELITKKEENEIL 807

Query: 689  KEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLE---KMSAEKIS-------EL--- 735
            KE++  T+K+L+ +KE+  N+ Q   +E  +   + E   K+  EKI+       EL   
Sbjct: 808  KEKINETLKELK-EKEESNNQYQQINEEMKEKLKEKENEIKIKEEKITNKEKEMEELKNN 866

Query: 736  LAKINHEEQSKIQTQFG-IDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYS 794
              K+ +E + + + +   ++ +I+E+   I+NI+ E   +   I   EE   + E+  +S
Sbjct: 867  FNKVENENEKRFKEKINELNKEIEEQKKSIKNIKEEEYLFADIILDNEEIKELKEEMIHS 926

Query: 795  -LERK---------ADQLGSYLQEKQKAYSEYTIQEDELVNRLAVL--MDHDRVVEKQLL 842
             L RK          +QL +  ++ +   S++ I+  ++ N+   L  ++  +  EK LL
Sbjct: 927  KLNRKMIELIKKKEMEQLINDKKDLEIQLSKHQIENQKIQNQNDELKKINQTKENEKVLL 986

Query: 843  -----EIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQ 897
                 +++++  EL++K++I  +EN  LQ  +++  +   +L EK    +L ++E+TK +
Sbjct: 987  NEINEKLQNKINELKEKDKIQEDENNKLQSEITNYSKTITSLTEK---IELCKTENTKIE 1043

Query: 898  TQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYV 957
             +++  E+ ++ I  E +  + +   EI+    +F    E+ I++++++       I  +
Sbjct: 1044 NKIQQKENEIEEIKKEKEIALEELNHEIKKKIKDF----ENQIKEQEIIQ---NNQIITI 1096

Query: 958  TQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNAL 1017
             + +  + E K +IE +   +EE      E  +  + K + ++     +    I K+  +
Sbjct: 1097 KEKDQNIYELKQHIEKMKKIIEETPLKEYEEENNKILKLKEENELLENKNKENIQKIE-V 1155

Query: 1018 LKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQL-LDSKQ 1076
            LK+K+EE+    Q I   +++    ++    KL +     +N +E+M+   KQ  ++ ++
Sbjct: 1156 LKKKEEELNNKMQLIEQEKINLNKEINIEIQKLKEELENEKNEKEKMKDFIKQKEIELQK 1215

Query: 1077 HNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXX 1136
              +E + ++++   +I++ KE K+  + ++ K    I+   IE   +   N+        
Sbjct: 1216 EKDEKECIIQQ---KIRDEKE-KINAQESVRKMAEKIVQQKIE--ENQKKNI--LESLEE 1267

Query: 1137 XXXXXLKVQEEEEFIQ-ERSVLQEQSAKLNTELQECYTK 1174
                  K++ E+E I+ ++ ++++    L  E++E   K
Sbjct: 1268 EKRNRKKIENEKEIIEKDKEIMEKNINSLKEEIEELKKK 1306



 Score =  123 bits (297), Expect = 4e-26
 Identities = 195/932 (20%), Positives = 393/932 (42%), Gaps = 75/932 (8%)

Query: 692  LYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINH-----EEQSK 746
            L+G++ +   D E+     QN     +D          +K    L KIN      E++ K
Sbjct: 282  LFGSVNESSVDSEEDRKDQQNQTIPIIDSIGSSRIKKTQKEQRGLNKINSFDEVVEKKRK 341

Query: 747  IQTQFGIDAKIQERDLYIENIESELSKYKS--RICRLEESIAVMEDRRYSLER-KADQLG 803
               +    AK +   L  E I +E  K ++  ++ +LEE    M +++  +E+ K ++  
Sbjct: 342  EDLEKLKKAKEELSKLEEEKIAAEKEKEEANEKVQKLEEE---MREKKIEIEKLKVEREE 398

Query: 804  SY-LQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEEN 862
            S+ L + QK  S   IQ  E      +  + ++  + +  E E   K +++   I LE  
Sbjct: 399  SFRLLKGQKEQSLCEIQRVEQEKEKRIKEEVEKAHQLREKEFEELLKRIKELEAINLENE 458

Query: 863  QNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKK 922
             N         +  N   EK     + +    + + +++++E NL+    E+  +  + K
Sbjct: 459  YNKDELKKKCLEISNIQEEKEELILIVQEIKEENEKRIKEIE-NLQEKKEENARIFEEMK 517

Query: 923  KEIEDLE----IEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNV 978
            KEIE+ E    IE   +IE     +++ N K   N+E +T     LQ+  NN  +L   +
Sbjct: 518  KEIEEREKELIIERKQEIELQNEVQRITN-KSNNNVEKLTNQIEVLQKEINNQRSLLQEI 576

Query: 979  EELNKM-NLELIDKHVQKQQTQSPDYTEQYINEINKL-----NALLKQK---DEEIIALN 1029
            EE NK+ N E+ +  ++++QT+   +TE+ +N+I K      N ++K+     EEI  LN
Sbjct: 577  EEKNKLFNNEIKEAKIKEEQTKE-FFTEE-MNQITKKGEEERNRIMKENVIMKEEIKKLN 634

Query: 1030 QKINNAQVSYMSMV---SDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVR 1086
            ++       Y        D + KL     K E +E     +  Q+   K+  EEL+   +
Sbjct: 635  KEKEEMNEKYNKKEIENEDDKEKLKNEIQKREEIENNKISLQNQIFQLKKIIEELEEGNK 694

Query: 1087 EQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQE 1146
               ++I  L E     ++ I K +        +    +  N +            +K++E
Sbjct: 695  YNTNKINILTEECSKKDIEIEKIK--------KEFEQEIKN-EREEQIKEKEDEIIKIKE 745

Query: 1147 EEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQI--NQLKSKLE 1204
            E +  +E       + +   +L+      ++ E  N E     + NQ++I   +L +K E
Sbjct: 746  EMKMAEENYKNNISTIRTKKDLE---IHQLKEEEQNKEKEIDILTNQKEIISKELITKKE 802

Query: 1205 QLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAF 1264
            +     + +  T+ EL+    S  + +  +I E  K+ L ++E + +  E ++  +    
Sbjct: 803  ENEILKEKINETLKELKEKEES--NNQYQQINEEMKEKLKEKENEIKIKEEKITNK---- 856

Query: 1265 ESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEK---YADVINQIE 1321
            E + E+L ++      E   +    E++  L  +++++++ ++N++E+   +AD+I   E
Sbjct: 857  EKEMEELKNNFNKVENENEKRF--KEKINELNKEIEEQKKSIKNIKEEEYLFADIILDNE 914

Query: 1322 ILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYK-QMQEQSILN--INEENAQLK 1378
             ++ E+++E +                   L  + +  + Q+ +  I N  I  +N +LK
Sbjct: 915  EIK-ELKEEMIHSKLNRKMIELIKKKEMEQLINDKKDLEIQLSKHQIENQKIQNQNDELK 973

Query: 1379 KSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSE---IYQKTHEYTITLTQRNDEFE 1435
            K +                 + K+ EL  + ++++ E   +  +   Y+ T+T   ++ E
Sbjct: 974  KINQTKENEKVLLNEINEKLQNKINELKEKDKIQEDENNKLQSEITNYSKTITSLTEKIE 1033

Query: 1436 -------NVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLI 1488
                    +  ++ + E  IE++  EKE  L  L  ++ +    +E   KE EI +   I
Sbjct: 1034 LCKTENTKIENKIQQKENEIEEIKKEKEIALEELNHEIKKKIKDFENQIKEQEIIQNNQI 1093

Query: 1489 EELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVR 1548
              +  K      L + + ++ K +EE   K  E     EN +I  +   +E+   +N   
Sbjct: 1094 ITIKEKDQNIYELKQHIEKMKKIIEETPLKEYEE----ENNKILKLKEENELLENKNKEN 1149

Query: 1549 ASSSKIQKHVSFASDTKQGRDEQLDNTMNKEL 1580
                ++ K      + K    EQ    +NKE+
Sbjct: 1150 IQKIEVLKKKEEELNNKMQLIEQEKINLNKEI 1181



 Score =  123 bits (296), Expect = 5e-26
 Identities = 190/907 (20%), Positives = 404/907 (44%), Gaps = 92/907 (10%)

Query: 222  QENFIAMEAEWKDEKQRLLKDIES----KDVRISSLEEANKLLEAARFEISLEHSK---L 274
            +E  I +  E K+E ++ +K+IE+    K+      EE  K +E    E+ +E  +   L
Sbjct: 478  KEELILIVQEIKEENEKRIKEIENLQEKKEENARIFEEMKKEIEEREKELIIERKQEIEL 537

Query: 275  AQELEQXXXXXXXXXXXXXX---LAKQSIEPSCEEKTEIEEKGSLEIANMTELT-KKIEL 330
              E+++                 + ++ I        EIEEK  L    + E   K+ + 
Sbjct: 538  QNEVQRITNKSNNNVEKLTNQIEVLQKEINNQRSLLQEIEEKNKLFNNEIKEAKIKEEQT 597

Query: 331  LEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLS 390
             E    ++ Q  K+ E +   +  E+  +    KK   L   K   N     K   ++  
Sbjct: 598  KEFFTEEMNQITKKGEEERNRIMKENVIMKEEIKK---LNKEKEEMNEKYNKKEIENEDD 654

Query: 391  SETLNQDTDKK--INKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTL 448
             E L  +  K+  I  N+I+    + Q L K + + E                   KD  
Sbjct: 655  KEKLKNEIQKREEIENNKISLQNQIFQ-LKKIIEELEEGNKYNTNKINILTEECSKKDIE 713

Query: 449  IAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEI------KDVNVKDLI 502
            I +++ E +Q ++      +    +++ +I +  +  ++   + I      KD+ +  L 
Sbjct: 714  IEKIKKEFEQEIKNEREEQIKEKEDEIIKIKEEMKMAEENYKNNISTIRTKKDLEIHQLK 773

Query: 503  EKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTE 562
            E+ ++ E++I  L ++ +  +K +I  K  +++  +++ +T+    +  +SN +  ++ E
Sbjct: 774  EEEQNKEKEIDILTNQKEIISKELITKKEENEILKEKINETLKELKEKEESNNQYQQINE 833

Query: 563  ELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQ 622
            E   + +K+ E E E              ++ E  +  K  EME L     K  +  E +
Sbjct: 834  E---MKEKLKEKENEI-------------KIKEEKITNKEKEMEELKNNFNKVENENEKR 877

Query: 623  KFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVI 682
              + + EL+   ++  +    + +   L +D +    +   L+E++     ++K + L+ 
Sbjct: 878  FKEKINELNKEIEEQKKSIKNIKEEEYLFADIILDNEEIKELKEEMIHSKLNRKMIELI- 936

Query: 683  ENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISE--LLAKIN 740
               K + EQL    KDLE      ++K Q   Q+  +  D+L+K++  K +E  LL +IN
Sbjct: 937  --KKKEMEQLINDKKDLEIQ----LSKHQIENQKIQNQNDELKKINQTKENEKVLLNEIN 990

Query: 741  HEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKAD 800
             + Q+KI      D KIQE +     ++SE++ Y   I  L E I + +     +E K  
Sbjct: 991  EKLQNKINELKEKD-KIQEDE--NNKLQSEITNYSKTITSLTEKIELCKTENTKIENKIQ 1047

Query: 801  QLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQ--KKNQIL 858
            Q  + ++E +K   E  ++E          ++H+  ++K++ + E++ KE +  + NQI+
Sbjct: 1048 QKENEIEEIKKE-KEIALEE----------LNHE--IKKKIKDFENQIKEQEIIQNNQII 1094

Query: 859  L--EENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQT 916
               E++QN+     +++QH   + +    T L E E         +  + + ++  E++ 
Sbjct: 1095 TIKEKDQNIY----ELKQHIEKMKKIIEETPLKEYE---------EENNKILKLKEENEL 1141

Query: 917  LIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNM 976
            L  + K+ I+  +IE   + E  + +K  L E+ + N+    ++  ++Q+ K  +EN   
Sbjct: 1142 LENKNKENIQ--KIEVLKKKEEELNNKMQLIEQEKINLN--KEINIEIQKLKEELEN-EK 1196

Query: 977  NVEELNKMNLELIDKHVQKQQTQSPDYTEQYI-NEINKLNA--LLKQKDEEIIALNQKI- 1032
            N +E  K  ++  +  +QK++ +     +Q I +E  K+NA   +++  E+I+   QKI 
Sbjct: 1197 NEKEKMKDFIKQKEIELQKEKDEKECIIQQKIRDEKEKINAQESVRKMAEKIV--QQKIE 1254

Query: 1033 NNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQI 1092
             N + + +  + + +    +   + E +E++ + + K +   K+  EEL+   +++ + I
Sbjct: 1255 ENQKKNILESLEEEKRNRKKIENEKEIIEKDKEIMEKNINSLKEEIEELKKKDKKKIEDI 1314

Query: 1093 KELKETK 1099
            K ++  K
Sbjct: 1315 KLIELIK 1321



 Score = 84.6 bits (200), Expect = 2e-14
 Identities = 160/790 (20%), Positives = 351/790 (44%), Gaps = 56/790 (7%)

Query: 144  VTHLSNTIKEK-DNALSVLQVKMKIMETTILDLQEKIN-EKDQIIEAKNKATTXXXXXXX 201
            +T+ SN   EK  N + VLQ ++    + + +++EK     ++I EAK K          
Sbjct: 544  ITNKSNNNVEKLTNQIEVLQKEINNQRSLLQEIEEKNKLFNNEIKEAKIKEEQTKEFFTE 603

Query: 202  XXXXXXXXXXEDTKQQMTK---MQENFIAMEAEWKDEKQRL-LKDIESKDVRISSLEEAN 257
                      E+  + M +   M+E    +  E ++  ++   K+IE++D +     E  
Sbjct: 604  EMNQITKKGEEERNRIMKENVIMKEEIKKLNKEKEEMNEKYNKKEIENEDDKEKLKNEIQ 663

Query: 258  KLLEAARFEISLEHS--KLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCE-EKTEIEEKG 314
            K  E    +ISL++   +L + +E+              L ++  +   E EK + E + 
Sbjct: 664  KREEIENNKISLQNQIFQLKKIIEELEEGNKYNTNKINILTEECSKKDIEIEKIKKEFEQ 723

Query: 315  SLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKS 374
             ++     ++ +K + +  +  +++   +  +N ++T+ T+        K+      ++ 
Sbjct: 724  EIKNEREEQIKEKEDEIIKIKEEMKMAEENYKNNISTIRTKKDLEIHQLKEEEQNKEKEI 783

Query: 375  GRNTASKMKSPWSQLSSETLNQDTDKKINK--NEIAKLE---MVIQSLNKDLVDKEYVIS 429
               T  K       ++ +  N+   +KIN+   E+ + E      Q +N+++ +K   + 
Sbjct: 784  DILTNQKEIISKELITKKEENEILKEKINETLKELKEKEESNNQYQQINEEMKEK---LK 840

Query: 430  EKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAK-VQEQLKQE 488
            EK+            K+  + +L+  +   +E  +        E +NE+ K ++EQ K  
Sbjct: 841  EKENEIKIKEEKITNKEKEMEELK-NNFNKVENENEKRF---KEKINELNKEIEEQKKSI 896

Query: 489  LNDEIKDVNVKDLI---EKLKSAEEQI--TQLNDE-IDAANKNMIKVKSNHKLKLK-QMQ 541
             N + ++    D+I   E++K  +E++  ++LN + I+   K  ++   N K  L+ Q+ 
Sbjct: 897  KNIKEEEYLFADIILDNEEIKELKEEMIHSKLNRKMIELIKKKEMEQLINDKKDLEIQLS 956

Query: 542  KTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKK 601
            K      K+ + N E+ ++ +   +    + E+ E+  N    L + D  ++ E +  K 
Sbjct: 957  KHQIENQKIQNQNDELKKINQTKENEKVLLNEINEKLQNKINELKEKD--KIQEDENNKL 1014

Query: 602  MIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKS 661
              E+ N ++T       +E  K +  +  + +QQK +E+E+ +    ++  +++  EIK 
Sbjct: 1015 QSEITNYSKTITSLTEKIELCKTENTKIENKIQQKENEIEE-IKKEKEIALEELNHEIKK 1073

Query: 662  --VHLEEQIDALSASKKELALVIE-------NLKLDKEQLYGTIKDLE-NDKEDIMNKLQ 711
                 E QI      +    + I+        LK   E++   I++    + E+  NK+ 
Sbjct: 1074 KIKDFENQIKEQEIIQNNQIITIKEKDQNIYELKQHIEKMKKIIEETPLKEYEEENNKIL 1133

Query: 712  NYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQ--TQFGIDAKIQERDLYIENIES 769
               +EN +L +   K + +KI E+L K   E  +K+Q   Q  I+   +E ++ I+ ++ 
Sbjct: 1134 KLKEEN-ELLENKNKENIQKI-EVLKKKEEELNNKMQLIEQEKINLN-KEINIEIQKLKE 1190

Query: 770  ELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAV 829
            EL   K+   ++++ I   + +   L+++ D+    +Q+K +   E  I   E V ++A 
Sbjct: 1191 ELENEKNEKEKMKDFI---KQKEIELQKEKDEKECIIQQKIRDEKE-KINAQESVRKMAE 1246

Query: 830  LMDHDRVVEKQLLEIEHENKELQKKNQILLE-ENQNLQISLSDMQQHYNAL---VEKANR 885
             +   ++ E Q   I  E+ E +K+N+  +E E + ++     M+++ N+L   +E+  +
Sbjct: 1247 KIVQQKIEENQKKNI-LESLEEEKRNRKKIENEKEIIEKDKEIMEKNINSLKEEIEELKK 1305

Query: 886  TDLAESESTK 895
             D  + E  K
Sbjct: 1306 KDKKKIEDIK 1315



 Score = 48.4 bits (110), Expect = 0.002
 Identities = 66/344 (19%), Positives = 142/344 (41%), Gaps = 28/344 (8%)

Query: 1262 SAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQ-- 1319
            S F S  E  +DS +    ++   I  ++ + S + K   KE+   N    + +V+ +  
Sbjct: 281  SLFGSVNESSVDSEEDRKDQQNQTIPIIDSIGSSRIKKTQKEQRGLNKINSFDEVVEKKR 340

Query: 1320 ---IEILR------SEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNI 1370
               +E L+      S++E+EK+A                 ++R +    ++++ +   + 
Sbjct: 341  KEDLEKLKKAKEELSKLEEEKIAAEKEKEEANEKVQKLEEEMREKKIEIEKLKVEREESF 400

Query: 1371 NEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQ------LELKDSEIYQKTHEYT 1424
                 Q ++S             R+ +   K  +L  +        +K+ E     +EY 
Sbjct: 401  RLLKGQKEQSLCEIQRVEQEKEKRIKEEVEKAHQLREKEFEELLKRIKELEAINLENEYN 460

Query: 1425 IT-LTQRNDEFENVRQQLVEYEKRIEDLTYEKES---ELAILRLKMHENANHYETMQKES 1480
               L ++  E  N++++  E    ++++  E E    E+  L+ K  ENA  +E M+KE 
Sbjct: 461  KDELKKKCLEISNIQEEKEELILIVQEIKEENEKRIKEIENLQEKKEENARIFEEMKKEI 520

Query: 1481 EIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEI 1540
            E    +LI E   +I     + +   + N  +E+   +   +Q  + NQ   +  + ++ 
Sbjct: 521  EEREKELIIERKQEIELQNEVQRITNKSNNNVEKLTNQIEVLQKEINNQRSLLQEIEEKN 580

Query: 1541 TNLQNMVRASSSKIQKHVSFASD-----TKQGRDEQLDNTMNKE 1579
                N ++ +  K ++   F ++     TK+G +E+  N + KE
Sbjct: 581  KLFNNEIKEAKIKEEQTKEFFTEEMNQITKKGEEER--NRIMKE 622


>UniRef50_Q10411 Cluster: Sporulation-specific protein 15; n=1;
            Schizosaccharomyces pombe|Rep: Sporulation-specific
            protein 15 - Schizosaccharomyces pombe (Fission yeast)
          Length = 1957

 Score =  144 bits (348), Expect = 2e-32
 Identities = 281/1465 (19%), Positives = 608/1465 (41%), Gaps = 132/1465 (9%)

Query: 172  ILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAE 231
            I DL  +I+E D + +++    +                 +D++   ++++E  +    E
Sbjct: 321  IEDLSTRISEFDNL-KSERDTLSIKNEKLEKLLRNTIGSLKDSRTSNSQLEEEMV----E 375

Query: 232  WKDEKQRLLKDIESKDVRISSLEEANKLLEAARFE----ISLEHSKLAQELEQXXXXXXX 287
             K+  + +   +   + ++SS E+ NK L+ +  E    +S +   + Q   Q       
Sbjct: 376  LKESNRTIHSQLTDAESKLSSFEQENKSLKGSIDEYQNNLSSKDKMVKQVSSQLEEARSS 435

Query: 288  XXXXXXXLAKQSIEPSCEEKT-----EIEE-------KGSLEIANMTELT-KKIELLEHL 334
                   LA+ + E   + K      +IE+         S E+   + L  KK + L +L
Sbjct: 436  LAHATGKLAEINSERDFQNKKIKDFEKIEQDLRACLNSSSNELKEKSALIDKKDQELNNL 495

Query: 335  NCQIRQTNKELENKLATMGTESKAVSSPSKKG----SPLISRKSGRNTA-SKMKSPWSQL 389
              QI++  K  E+  +++ +  + + +  KK     S L   K    T  S  +   SQL
Sbjct: 496  REQIKEQKKVSESTQSSLQSLQRDILNEKKKHEVYESQLNELKGELQTEISNSEHLSSQL 555

Query: 390  SSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDK--EYVISEKDTXXXXXXXXXXGKDT 447
            S+    ++     N NE+++ +  +Q+L     +K  + V+  K+            K  
Sbjct: 556  STLAAEKEAAVATN-NELSESKNSLQTLCNAFQEKLAKSVMQLKENEQNFSSLDTSFKKL 614

Query: 448  LIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKS 507
              +  +LE+        L    +  + +       EQ +  L+DE  D+  K L  KL+ 
Sbjct: 615  NESHQELENNHQTITKQLKDTSSKLQQLQLERANFEQKESTLSDENNDLRTKLL--KLEE 672

Query: 508  AEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHL 567
            + + + +  +++D+  KN+  +K +    L++ ++ +  FSK+   N     L E + +L
Sbjct: 673  SNKSLIKKQEDVDSLEKNIQTLKED----LRKSEEAL-RFSKLEAKN-----LREVIDNL 722

Query: 568  SQKVAELEEEKGNLQLHLVDY-DSGRMIESDVYKKMIEMENLA---ETRLKAISLLESQK 623
              K   LE ++ +L   L D  ++  ++ S++ K   +++ L    ET  +    ++   
Sbjct: 723  KGKHETLEAQRNDLHSSLSDAKNTNAILSSELTKSSEDVKRLTANVETLTQDSKAMKQSF 782

Query: 624  FDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIE 683
              LV     +   Y E+ D   ++    +  + SE K   L+   + L+     L   ++
Sbjct: 783  TSLVNSYQSISNLYHELRDDHVNMQSQNNTLLESESK---LKTDCENLTQQNMTLIDNVQ 839

Query: 684  NLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEE 743
             L          + +L+     +   L+N ++ ++++          +++EL    +  E
Sbjct: 840  KLMHKHVNQESKVSELKEVNGKLSLDLKN-LRSSLNVAISDNDQILTQLAELSKNYDSLE 898

Query: 744  QSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLG 803
            Q   Q   G+ +   E+ L    + +E  +   R+ +L   + + E +   L +K     
Sbjct: 899  QESAQLNSGLKSLEAEKQL----LHTENEELHIRLDKLTGKLKIEESKSSDLGKKL---- 950

Query: 804  SYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQL-LEIEH-ENK--ELQKKNQILL 859
            +  QE+     E  + + + +  +   +D       +L  +IEH +NK  E++ +   LL
Sbjct: 951  TARQEEISNLKEENMSQSQAITSVKSKLDETLSKSSKLEADIEHLKNKVSEVEVERNALL 1010

Query: 860  EENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIV 919
              N+ L   L +  ++  +L          ++E  K + +  DL+S L  ++ E++ L++
Sbjct: 1011 ASNERLMDDLKNNGENIASL----------QTEIEKKRAENDDLQSKLSVVSSEYENLLL 1060

Query: 920  QKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEY--VTQLEAQLQEYKNNIENLNMN 977
               +  + LE + N         +K+L+EK ++N+E   +T    +L E    I++  + 
Sbjct: 1061 ISSQTNKSLEDKTNQLKYIEKNVQKLLDEKDQRNVELEELTSKYGKLGEENAQIKDELLA 1120

Query: 978  VEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQV 1037
            + + +K   +L    V   + +S D  EQ  NE N+L   L+Q +      N+ +   + 
Sbjct: 1121 LRKKSKKQHDLCANFVDDLKEKS-DALEQLTNEKNELIVSLEQSNSN----NEALVEERS 1175

Query: 1038 SYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQI----LVREQDDQIK 1093
               + +SD +  L+     +  +  ++ RV+ +L   K+  + L      + +++DD + 
Sbjct: 1176 DLANRLSDMKKSLSDSDNVISVIRSDLVRVNDELDTLKKDKDSLSTQYSEVCQDRDDLLD 1235

Query: 1094 ELKETKLTFEMNIPKTEGMIISSTIE-PMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQ 1152
             LK  + +F         +   S I+ P+S+  ++              L V   E ++ 
Sbjct: 1236 SLKGCEESFNKYAVSLRELCTKSEIDVPVSEILDDNFVFNAGNFSELSRLTVLSLENYLD 1295

Query: 1153 ERSVLQEQSAKLNTELQEC---YTKII-QLETLNTELTGHDVVNQEQINQLKSKLEQLNT 1208
              + +  +  +L+  L      +TK++  LE L  E   HD    + + Q     + L  
Sbjct: 1296 AFNQVNFKKMELDNRLTTTDAEFTKVVADLEKLQHE---HD----DWLIQRGDLEKALKD 1348

Query: 1209 ENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKY 1268
               N L   AE+  +I S   + G E  +     L+ R  D Q   ++L+ QL     + 
Sbjct: 1349 SEKNFLRKEAEMTENIHSL--EEGKEETKKEIAELSSRLEDNQLATNKLKNQLDHLNQEI 1406

Query: 1269 EQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIE 1328
             +L + V    +E+ + I+++E+  SL N+ Q KE  L + + +   +++      S + 
Sbjct: 1407 -RLKEDV---LKEKESLIISLEE--SLSNQRQ-KESSLLDAKNELEHMLDDTSRKNSSLM 1459

Query: 1329 DEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXX 1388
            ++  +                  L     + +++  +S+  +    +QL+++        
Sbjct: 1460 EKIESINSSLDDKSFELASAVEKLG----ALQKLHSESLSLMENIKSQLQEAKE------ 1509

Query: 1389 XXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRI 1448
                 ++   E+ + EL H++    +    K ++    +   ++  E +   L E +  +
Sbjct: 1510 -----KIQVDESTIQELDHEITASKNNYEGKLNDKDSIIRDLSENIEQLNNLLAEEKSAV 1564

Query: 1449 EDLTYEKESELAILRLKMHENANHYETMQKESEIERVKL-----IEELNVKITESVSLNK 1503
            + L+ EKESE  IL+         Y   Q ESE+ R KL      EEL +   E +SL  
Sbjct: 1565 KRLSTEKESE--ILQFNSRLADLEYHKSQVESELGRSKLKLASTTEELQLAENERLSLTT 1622

Query: 1504 QVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASD 1563
            ++ +    L+ +V   + ++ +L      + +L D + +LQ   +  S+ ++  +     
Sbjct: 1623 RMLD----LQNQVKDLSNIKDSLSEDLRTLRSLEDSVASLQKECKIKSNTVES-LQDVLT 1677

Query: 1564 TKQGRDEQLDNTMNKELLDAVPRAE 1588
            + Q R+ +L++ +++  +D + R +
Sbjct: 1678 SVQARNAELEDEVSRS-VDKIRRRD 1701



 Score =  134 bits (325), Expect = 1e-29
 Identities = 257/1356 (18%), Positives = 560/1356 (41%), Gaps = 117/1356 (8%)

Query: 310  IEEKGSLEIANMTELTKKIELLEH----LNCQIRQTNKELENKLA-TMGTESKAVSSPSK 364
            + +K +L +  + ++  K+  LEH    L+ Q+  +NK+ +N  + T  T  + VS   K
Sbjct: 129  VTQKSNL-LNELKQVRSKLAALEHENGILSLQLSSSNKKDKNTSSVTTLTSEEDVSYFQK 187

Query: 365  KGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDK 424
            K + + S  S + + +   S   QL   T+ +  DKK  + +  K++  + S+   L ++
Sbjct: 188  KLTNMESNFSAKQSEAYDLS--RQLL--TVTEKLDKK--EKDYEKIKEDVSSIKASLAEE 241

Query: 425  EYVI-SEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQE 483
            +    S +               T+    Q E+    E  +L           E +K+ E
Sbjct: 242  QASNKSLRGEQERLEKLLVSSNKTVSTLRQTENSLRAECKTLQEKLEKCAINEEDSKLLE 301

Query: 484  QLKQELNDEIKDVNVKD-LIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQK 542
            +LK  + +    +  KD LIE L +   +   L  E D      + +K N KL+ K ++ 
Sbjct: 302  ELKHNVANYSDAIVHKDKLIEDLSTRISEFDNLKSERDT-----LSIK-NEKLE-KLLRN 354

Query: 543  TIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDS-GRMIESDVYKK 601
            TI +      SN +   L EE+  L +    +  +  + +  L  ++   + ++  + + 
Sbjct: 355  TIGSLKDSRTSNSQ---LEEEMVELKESNRTIHSQLTDAESKLSSFEQENKSLKGSIDEY 411

Query: 602  MIEMENLAETRLKAISLLESQKFDLVQ---ELHILQQKYDEVEDKLADISQLQSD-QVCS 657
               + +  +   +  S LE  +  L     +L  +  + D    K+ D  +++ D + C 
Sbjct: 412  QNNLSSKDKMVKQVSSQLEEARSSLAHATGKLAEINSERDFQNKKIKDFEKIEQDLRACL 471

Query: 658  EIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMN---KLQNYI 714
               S  L+E+   +    +EL  + E +K  K+    T   L++ + DI+N   K + Y 
Sbjct: 472  NSSSNELKEKSALIDKKDQELNNLREQIKEQKKVSESTQSSLQSLQRDILNEKKKHEVYE 531

Query: 715  QENMDLTDKL--EKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELS 772
             +  +L  +L  E  ++E +S  L+ +  E+++ + T   +              + +L+
Sbjct: 532  SQLNELKGELQTEISNSEHLSSQLSTLAAEKEAAVATNNELSESKNSLQTLCNAFQEKLA 591

Query: 773  KY-------KSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVN 825
            K        +     L+ S   + +    LE     +   L++      +  ++      
Sbjct: 592  KSVMQLKENEQNFSSLDTSFKKLNESHQELENNHQTITKQLKDTSSKLQQLQLERANFEQ 651

Query: 826  RLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNAL----VE 881
            + + L D +  +  +LL++E  NK L KK + +    +N+Q    D+++   AL    +E
Sbjct: 652  KESTLSDENNDLRTKLLKLEESNKSLIKKQEDVDSLEKNIQTLKEDLRKSEEALRFSKLE 711

Query: 882  KANRTDLAESESTKYQT---QLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIES 938
              N  ++ ++   K++T   Q  DL S+L    + +  L  +  K  ED++      +E+
Sbjct: 712  AKNLREVIDNLKGKHETLEAQRNDLHSSLSDAKNTNAILSSELTKSSEDVK-RLTANVET 770

Query: 939  AIRDKKVLNEKYE---KNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQK 995
              +D K + + +     + + ++ L  +L++   N+++ N  + E ++  L+   +++ +
Sbjct: 771  LTQDSKAMKQSFTSLVNSYQSISNLYHELRDDHVNMQSQNNTLLE-SESKLKTDCENLTQ 829

Query: 996  QQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYE---SKLAQ 1052
            Q     D  ++ +++     + + +  E    L+  + N + S    +SD +   ++LA+
Sbjct: 830  QNMTLIDNVQKLMHKHVNQESKVSELKEVNGKLSLDLKNLRSSLNVAISDNDQILTQLAE 889

Query: 1053 FTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGM 1112
             +   +++E+E  +++  L   K    E Q+L  E ++    ++  KLT ++ I +++  
Sbjct: 890  LSKNYDSLEQESAQLNSGL---KSLEAEKQLLHTENEE--LHIRLDKLTGKLKIEESKSS 944

Query: 1113 IISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECY 1172
             +   +    ++ +N+             +K  + +E + + S L+     L  ++ E  
Sbjct: 945  DLGKKLTARQEEISNLKEENMSQSQAITSVK-SKLDETLSKSSKLEADIEHLKNKVSEVE 1003

Query: 1173 TKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISS--AVDQ 1230
             +   L   N  L      N E I  L++++E+   END+L S ++ + S   +   +  
Sbjct: 1004 VERNALLASNERLMDDLKNNGENIASLQTEIEKKRAENDDLQSKLSVVSSEYENLLLISS 1063

Query: 1231 RGFEIAELWKQHLAQREADFQK---TEHELRVQLSAFESKY-------EQLLDSV----- 1275
            +  +  E     L   E + QK    + +  V+L    SKY        Q+ D +     
Sbjct: 1064 QTNKSLEDKTNQLKYIEKNVQKLLDEKDQRNVELEELTSKYGKLGEENAQIKDELLALRK 1123

Query: 1276 QSSTQEE---------TNKIVTMEQVTSLQNK----LQDKEEHLRNLQEKYADVINQIEI 1322
            +S  Q +           K   +EQ+T+ +N+    L+    +   L E+ +D+ N++  
Sbjct: 1124 KSKKQHDLCANFVDDLKEKSDALEQLTNEKNELIVSLEQSNSNNEALVEERSDLANRLSD 1183

Query: 1323 LRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLK--KS 1380
            ++  + D                      L+ +  S      +   + ++    LK  + 
Sbjct: 1184 MKKSLSDSDNVISVIRSDLVRVNDELDT-LKKDKDSLSTQYSEVCQDRDDLLDSLKGCEE 1242

Query: 1381 SXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTI-TLTQRNDEFENVRQ 1439
            S              ++ +  V E+     + ++  + +    T+ +L    D F  V  
Sbjct: 1243 SFNKYAVSLRELCTKSEIDVPVSEILDDNFVFNAGNFSELSRLTVLSLENYLDAFNQVNF 1302

Query: 1440 QLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELN-----VK 1494
            + +E + R+     E    +A L    HE   H + + +  ++E+     E N      +
Sbjct: 1303 KKMELDNRLTTTDAEFTKVVADLEKLQHE---HDDWLIQRGDLEKALKDSEKNFLRKEAE 1359

Query: 1495 ITESV--------SLNKQVAELNKALEEEVAKTNEMQTALE--NQEIEIV--TLNDEITN 1542
            +TE++           K++AEL+  LE+    TN+++  L+  NQEI +    L ++ + 
Sbjct: 1360 MTENIHSLEEGKEETKKEIAELSSRLEDNQLATNKLKNQLDHLNQEIRLKEDVLKEKESL 1419

Query: 1543 LQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNK 1578
            + ++  + S++ QK  S   D K   +  LD+T  K
Sbjct: 1420 IISLEESLSNQRQKESSLL-DAKNELEHMLDDTSRK 1454



 Score = 87.8 bits (208), Expect = 2e-15
 Identities = 198/1001 (19%), Positives = 418/1001 (41%), Gaps = 109/1001 (10%)

Query: 177  EKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEK 236
            + +  + Q++  +N+                     D  +++T  QE    ++ E   + 
Sbjct: 909  KSLEAEKQLLHTENEELHIRLDKLTGKLKIEESKSSDLGKKLTARQEEISNLKEENMSQS 968

Query: 237  QRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSK-LAQELEQXXXXXXXXXXXXXXL 295
            Q +   ++SK      L+E   L ++++ E  +EH K    E+E                
Sbjct: 969  QAITS-VKSK------LDET--LSKSSKLEADIEHLKNKVSEVEVERNALLASNERLMDD 1019

Query: 296  AKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTE 355
             K + E     +TEIE+K +      ++L+      E+L     QTNK LE+K   +   
Sbjct: 1020 LKNNGENIASLQTEIEKKRAENDDLQSKLSVVSSEYENLLLISSQTNKSLEDKTNQLKYI 1079

Query: 356  SKAVSSPSKKGSPLISRKSGRNT-ASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVI 414
             K V         L+  K  RN    ++ S + +L  E      +    + +  K   + 
Sbjct: 1080 EKNVQK-------LLDEKDQRNVELEELTSKYGKLGEENAQIKDELLALRKKSKKQHDLC 1132

Query: 415  QSLNKDLVDK----EYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGT 470
             +   DL +K    E + +EK+             + L+ +      +  +    +    
Sbjct: 1133 ANFVDDLKEKSDALEQLTNEKNELIVSLEQSNSNNEALVEERSDLANRLSDMKKSLSDSD 1192

Query: 471  NTEDV--NEIAKVQEQL------KQELNDEIKDV--NVKDLIEKLKSAEEQITQLNDEID 520
            N   V  +++ +V ++L      K  L+ +  +V  +  DL++ LK  EE   +      
Sbjct: 1193 NVISVIRSDLVRVNDELDTLKKDKDSLSTQYSEVCQDRDDLLDSLKGCEESFNKY----- 1247

Query: 521  AANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTE-ELHHLSQKVAELEEEKG 579
            A +   +  KS   + + ++    DNF   + +  E+ RLT   L +      ++  +K 
Sbjct: 1248 AVSLRELCTKSEIDVPVSEILD--DNFVFNAGNFSELSRLTVLSLENYLDAFNQVNFKKM 1305

Query: 580  NLQLHLVDYDSG-RMIESDVYKKMIEMEN-LAETRLKAISLLESQK------FDLVQELH 631
             L   L   D+    + +D+ K   E ++ L +      +L +S+K       ++ + +H
Sbjct: 1306 ELDNRLTTTDAEFTKVVADLEKLQHEHDDWLIQRGDLEKALKDSEKNFLRKEAEMTENIH 1365

Query: 632  ILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQ 691
             L++  +E + ++A++S    D   +++ +  L+ Q+D L+   +E+ L  + LK +KE 
Sbjct: 1366 SLEEGKEETKKEIAELSSRLED---NQLATNKLKNQLDHLN---QEIRLKEDVLK-EKES 1418

Query: 692  LYGTIKD-LEN--DKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHE--EQSK 746
            L  ++++ L N   KE  +   +N ++  +D T +      EKI  + + ++ +  E + 
Sbjct: 1419 LIISLEESLSNQRQKESSLLDAKNELEHMLDDTSRKNSSLMEKIESINSSLDDKSFELAS 1478

Query: 747  IQTQFGIDAKIQERDL-YIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSY 805
               + G   K+    L  +ENI+S+L + K +I +++ES   +++  + +    +     
Sbjct: 1479 AVEKLGALQKLHSESLSLMENIKSQLQEAKEKI-QVDES--TIQELDHEITASKNNYEGK 1535

Query: 806  LQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNL 865
            L +K     + +   ++L N LA   +    V++  L  E E++ LQ  +++   E    
Sbjct: 1536 LNDKDSIIRDLSENIEQLNNLLA---EEKSAVKR--LSTEKESEILQFNSRLADLEYHKS 1590

Query: 866  QISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLI--VQKKK 923
            Q+  S++ +    L        LAE+E     T++ DL++ +K +++   +L   ++  +
Sbjct: 1591 QVE-SELGRSKLKLASTTEELQLAENERLSLTTRMLDLQNQVKDLSNIKDSLSEDLRTLR 1649

Query: 924  EIED----LEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVE 979
             +ED    L+ E   +  +    + VL     +N E   ++   + + +   +       
Sbjct: 1650 SLEDSVASLQKECKIKSNTVESLQDVLTSVQARNAELEDEVSRSVDKIRRRDDRCEHLSG 1709

Query: 980  ELNKMNLELIDKH-----VQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINN 1034
            +L K++ +L ++H      ++Q+     + ++ + +  KL   L  + E++I       +
Sbjct: 1710 KLKKLHSQLEEQHETFFRAEQQRMTQLGFLKETVKKQEKLLKKLNLRQEQLIP-----RS 1764

Query: 1035 AQVSYMSMVSDYESKLAQFTTKLENMEEEMQ-------------RVSKQLLDS-KQHNEE 1080
            + + Y S + D E ++     +L  +E   Q             RV  ++LDS KQ   +
Sbjct: 1765 SILVYESYIRDIEKEIIVLQERLNGIELSQQLPKGYFGYFFKTNRVEMEVLDSFKQQVAK 1824

Query: 1081 LQIL------VREQDDQIK---ELKETKLTFEMNIPKTEGM 1112
            LQ L      V+ ++D  K   E KE + TF+    K E +
Sbjct: 1825 LQFLAGAEFIVKFKEDLEKCAAEEKEKQATFDNYSEKVENL 1865



 Score = 37.1 bits (82), Expect = 4.0
 Identities = 36/172 (20%), Positives = 75/172 (43%), Gaps = 14/172 (8%)

Query: 1428 TQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKL 1487
            T R  E  ++R +    ++++E     +E    +  LK H  AN+ + +     + + KL
Sbjct: 268  TLRQTE-NSLRAECKTLQEKLEKCAINEEDSKLLEELK-HNVANYSDAI-----VHKDKL 320

Query: 1488 IEELNVKITESVSLNKQ-------VAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEI 1540
            IE+L+ +I+E  +L  +         +L K L   +    + +T+    E E+V L +  
Sbjct: 321  IEDLSTRISEFDNLKSERDTLSIKNEKLEKLLRNTIGSLKDSRTSNSQLEEEMVELKESN 380

Query: 1541 TNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDLA 1592
              + + +  + SK+          K   DE  +N  +K+ +     ++L+ A
Sbjct: 381  RTIHSQLTDAESKLSSFEQENKSLKGSIDEYQNNLSSKDKMVKQVSSQLEEA 432


>UniRef50_A0CQM3 Cluster: Chromosome undetermined scaffold_24, whole
            genome shotgun sequence; n=2; Paramecium tetraurelia|Rep:
            Chromosome undetermined scaffold_24, whole genome shotgun
            sequence - Paramecium tetraurelia
          Length = 1305

 Score =  143 bits (347), Expect = 3e-32
 Identities = 220/1150 (19%), Positives = 492/1150 (42%), Gaps = 86/1150 (7%)

Query: 475  VNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHK 534
            V++I +++ +L Q   D   + N K L+E      E+   L  +I+   K ++++KS   
Sbjct: 155  VDQIQELERKLLQVQQDSRDNDNSKVLLE------EKCKHLEFQIENREKEILRLKSKLD 208

Query: 535  LKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMI 594
            ++   ++K       +S++ ++  R   +L  L+++  +L +E  NL+  L  +      
Sbjct: 209  IQGTNIEKLAQEHI-LSEAQQKAQRTQTQLDLLTEENTKLNDELSNLRKELQRFRKKPSQ 267

Query: 595  ESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELH-ILQQKYDEVEDKLADISQLQSD 653
              +      + +N      + +S++E +K    ++   IL Q   E    +  + QLQ  
Sbjct: 268  PQNSSPNKSDKKNELNQIKQRLSVIEDEKEKNQEQFKKILSQLEYENSQLIEKVQQLQQQ 327

Query: 654  QVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDI---MNKL 710
                ++K+++ E+ + A    K   +  + NLK DKE    T+K LE D + +   +N++
Sbjct: 328  NEQLQLKALNAEQVVSAYQTDKMVFSKAVNNLKSDKENTVQTLKSLEEDNQKLRFQLNEM 387

Query: 711  QNYIQENMDLTDKLEKMSAEKISELLAKIN--HEEQSKIQTQFGIDAKIQERDLYIENIE 768
             + +Q       +L++   E       K+N  +E + +   Q   D +  ER+L  +  +
Sbjct: 388  DDQLQIQKSEYQQLQR-EKELYDRNYKKLNDEYEREKEFVQQLRQDKRDLEREL--DQEK 444

Query: 769  SELSKYKSRICRLEESIAVMED--RRYSLERKADQLGSY---LQEKQKAYSEYTIQEDEL 823
              + + K    R++ S   ++   +++  E+K  Q        Q +Q    +   + D L
Sbjct: 445  QVIRELKVEFERMDVSKQNLDSLLQKFKQEQKNQQQSQQHNPNQGQQLMMDQLRKENDLL 504

Query: 824  VNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQI-------LLEENQNLQISLSDMQQHY 876
               +       + ++++L E + +N EL+++ ++       L ++N NL   +    Q  
Sbjct: 505  TKEVQTTEGLIKSIKRELGEKDRDNYELKQQKRLLNDQLSELAQKNANLDSQIKLKLQDI 564

Query: 877  NALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQK----KKEIEDLEIEF 932
              L ++  +    +S+    Q  + + +  ++  T     L+ Q+    K +I DL I F
Sbjct: 565  AQLEQEVEQYKREQSKMRLNQQSILEQKQKIENETVGELKLLQQQNNSLKLQISDLGI-F 623

Query: 933  NTQIESAIR-DKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVE-ELNKMNLELID 990
            N+Q+E  ++  +++LNE+  +N +    L  Q  E     +N+  N + E++  NL    
Sbjct: 624  NSQLEEKLKIAQELLNEQRLENDKLQMNLRQQSDETFKYQQNVLRNKDKEMDYYNLTHEI 683

Query: 991  KHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSM-------- 1042
            + ++ Q+ +     E++ +E  KL +++ Q+ +++  LN+    A      +        
Sbjct: 684  ERLRDQERKILIEKERFQSENLKLESVINQQTKQMEFLNKLKEEAMKEARELRQMINGLK 743

Query: 1043 VSDYESK--LAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKL 1100
             +D+E K    + + K+ N E  +Q +++QL      + +L   + E   QI  LK  K 
Sbjct: 744  TNDHEIKNTSIKLSEKVNNYEMSLQDINEQLQKEISRSNKLYNELTESQSQISSLKLQKT 803

Query: 1101 TFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQ 1160
             +E  I + +  ++  ++E   ++                  K+++E + +Q R + +  
Sbjct: 804  DYENQIRQLK--LLCESLEKQKEE-------LLQRLQQKNSTKIEDERQVLQLRELNENL 854

Query: 1161 SAKLNTELQECYTKIIQLETLNTELTGHDVVNQ-EQINQLKSKLEQLNTENDNLLSTVAE 1219
              K+N   ++       LE L  +L   +V NQ +++ +    L+Q   + +N +     
Sbjct: 855  EDKVNQYSEQNIQLKRSLEQL--DLERDEVQNQLDEVRETNISLQQQIKQMNNEIQKQQS 912

Query: 1220 LRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHE---LRVQLSAFESKYEQLLDSVQ 1276
              S +S+   +RG+E A+  ++ L  +    QK ++E   ++  L   E ++ ++   +Q
Sbjct: 913  KLSEVSTK-GERGYEAAQQLEEKLRDQIYKNQKLQNENDNVKYTLQIKEKEFHEMKSDIQ 971

Query: 1277 SSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXX 1336
              +++  N+ +  + + S+Q K + +++ ++ LQ++   +  QI++   E+ D ++ +  
Sbjct: 972  ILSKD--NQSLNNQLIKSVQEK-ELQQQQIQFLQQQEIRLKEQIKMFDMEMHDLQLNYSE 1028

Query: 1337 XXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVN 1396
                             T +     +Q + +L   +   +L+K              R +
Sbjct: 1029 VCAENQRL---------TVSIQQISLQHEEVL---QRGVELEKQEDFFKVQMQNASKRED 1076

Query: 1397 DAEAKVLELTHQLE---LKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTY 1453
              + ++ +   ++E    K  E  ++  E      Q   EF + R+    ++   ED  +
Sbjct: 1077 QYQIQLQQYEREIERLNRKSEEYERQIRELLKDRDQLGKEFHSQRKISTGFQAAQED--F 1134

Query: 1454 EKESELAILRLKMHENANHYETMQKESEIERVKLI-EELNVKITESVSLNKQVAELNKAL 1512
             ++        +  ENAN    +QK+ +++  +L  E+  V   E V + ++  ++N   
Sbjct: 1135 NRQIAQLEREKQYIENAN--RDLQKQVDLKDAQLSWEQKRVNEMEQVIIQERQMQMNTLQ 1192

Query: 1513 EEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRD-EQ 1571
            E +  K    Q   E ++        +  N Q+M          ++S  S     +D  Q
Sbjct: 1193 EIQQLKDQNEQLLQELEKAYQPQKYSQSNNKQSM-NLDYKNESSYISQQSQQSGVKDNSQ 1251

Query: 1572 LDNTMNKELL 1581
            LD +   E L
Sbjct: 1252 LDQSSGWERL 1261



 Score =  100 bits (239), Expect = 4e-19
 Identities = 171/909 (18%), Positives = 384/909 (42%), Gaps = 102/909 (11%)

Query: 306  EKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKL-------ATMGTESKA 358
            E  +++ +  L   N  +L  + E  +    Q+RQ  ++LE +L         +  E + 
Sbjct: 397  EYQQLQREKELYDRNYKKLNDEYEREKEFVQQLRQDKRDLERELDQEKQVIRELKVEFER 456

Query: 359  VSSPSKKGSPLISR-----KSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMV 413
            +    +    L+ +     K+ + +     +   QL  + L ++ D  +   E+   E +
Sbjct: 457  MDVSKQNLDSLLQKFKQEQKNQQQSQQHNPNQGQQLMMDQLRKEND--LLTKEVQTTEGL 514

Query: 414  IQSLNKDLVDKE---YVISEKDTXXXXXXXXXXGKDTL-----------IAQLQLEHQQH 459
            I+S+ ++L +K+   Y + ++             K+             IAQL+ E +Q+
Sbjct: 515  IKSIKRELGEKDRDNYELKQQKRLLNDQLSELAQKNANLDSQIKLKLQDIAQLEQEVEQY 574

Query: 460  MEGPSLIHVGTNT----------EDVNEIAKVQEQLKQELNDEIKDVNV--KDLIEKLKS 507
                S + +   +          E V E+  +Q+Q    L  +I D+ +    L EKLK 
Sbjct: 575  KREQSKMRLNQQSILEQKQKIENETVGELKLLQQQ-NNSLKLQISDLGIFNSQLEEKLKI 633

Query: 508  AEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHL 567
            A+E + +   E D    N ++ +S+   K +Q      N  +  D   +   LT E+  L
Sbjct: 634  AQELLNEQRLENDKLQMN-LRQQSDETFKYQQ------NVLRNKDKEMDYYNLTHEIERL 686

Query: 568  SQKVAELEEEKGNLQLHLVDYDS--GRMIESDVYKKMIEMENLAETR--LKAISLLESQK 623
              +  ++  EK   Q   +  +S   +  +   +   ++ E + E R   + I+ L++  
Sbjct: 687  RDQERKILIEKERFQSENLKLESVINQQTKQMEFLNKLKEEAMKEARELRQMINGLKTND 746

Query: 624  FDLVQELHILQQKYDEVEDKLADIS-QLQ-----SDQVCSEIKSVHLEEQIDALSASKKE 677
             ++      L +K +  E  L DI+ QLQ     S+++ +E+     + QI +L   K +
Sbjct: 747  HEIKNTSIKLSEKVNNYEMSLQDINEQLQKEISRSNKLYNEL--TESQSQISSLKLQKTD 804

Query: 678  LALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLA 737
                I  LKL         + LE  KE+++ +LQ   + +  + D+ + +   +++E L 
Sbjct: 805  YENQIRQLKL-------LCESLEKQKEELLQRLQQ--KNSTKIEDERQVLQLRELNENLE 855

Query: 738  -KINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLE 796
             K+N   +  IQ    +   +++ DL  + ++++L + +     L++ I  M +    ++
Sbjct: 856  DKVNQYSEQNIQ----LKRSLEQLDLERDEVQNQLDEVRETNISLQQQIKQMNN---EIQ 908

Query: 797  RKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKE--LQKK 854
            ++  +L     + ++ Y      E++L          D++ + Q L+ E++N +  LQ K
Sbjct: 909  KQQSKLSEVSTKGERGYEAAQQLEEKL---------RDQIYKNQKLQNENDNVKYTLQIK 959

Query: 855  NQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEH 914
             +   E   ++QI   D Q   N L++     +L + +    Q Q   L+  +K    E 
Sbjct: 960  EKEFHEMKSDIQILSKDNQSLNNQLIKSVQEKELQQQQIQFLQQQEIRLKEQIKMFDMEM 1019

Query: 915  QTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENL 974
              L +   +   +     N ++  +I+    ++ ++E+ ++   +LE Q   +K  ++N 
Sbjct: 1020 HDLQLNYSEVCAE-----NQRLTVSIQQ---ISLQHEEVLQRGVELEKQEDFFKVQMQNA 1071

Query: 975  NMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINN 1034
            +   E+  ++ L+  ++ +++   +S +Y E+ I E+ K    L ++      ++     
Sbjct: 1072 SKR-EDQYQIQLQQYEREIERLNRKSEEY-ERQIRELLKDRDQLGKEFHSQRKISTGFQA 1129

Query: 1035 AQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQL-LDSKQHNEELQILVREQDDQIK 1093
            AQ  +   ++  E +         ++++++     QL  + K+ NE  Q++++E+  Q+ 
Sbjct: 1130 AQEDFNRQIAQLEREKQYIENANRDLQKQVDLKDAQLSWEQKRVNEMEQVIIQERQMQMN 1189

Query: 1094 ELKETKLTFEMNIPKTEGMIISSTIEPMS-DDANNVDXXXXXXXXXXXXLKVQEEEEFIQ 1152
             L+E +   + N    +   +    +P     +NN              +  Q ++  ++
Sbjct: 1190 TLQEIQQLKDQNEQLLQE--LEKAYQPQKYSQSNNKQSMNLDYKNESSYISQQSQQSGVK 1247

Query: 1153 ERSVLQEQS 1161
            + S L + S
Sbjct: 1248 DNSQLDQSS 1256



 Score = 98.7 bits (235), Expect = 1e-18
 Identities = 171/921 (18%), Positives = 389/921 (42%), Gaps = 78/921 (8%)

Query: 704  EDIMNKLQNYIQENMDLTDKLE--KMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERD 761
            E ++N L    +    L  +LE  K++A K  +LL  +  E Q  +     +   + +  
Sbjct: 32   ERLLNDLVKTTEGFQQLKKQLEETKINAAKFEQLLLPLKKENQRIVNENNQLHMTMIQIK 91

Query: 762  LYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQED 821
               E  +++ +K++S++  LE       D ++ L +K +      +E  K  +E    + 
Sbjct: 92   ---EECDTKENKWRSQVRMLESE---RNDWKFILGQKNNAEKKLQEELFKKNNENNYSQS 145

Query: 822  ELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDM--------- 872
               ++   L+D  + +E++LL+++ ++++      +L E+ ++L+  + +          
Sbjct: 146  NQPDKTLKLVDQIQELERKLLQVQQDSRDNDNSKVLLEEKCKHLEFQIENREKEILRLKS 205

Query: 873  -------------QQHY-NALVEKANRT----DLAESESTKYQTQLRDLESNLKRITHE- 913
                         Q+H  +   +KA RT    DL   E+TK   +L +L   L+R   + 
Sbjct: 206  KLDIQGTNIEKLAQEHILSEAQQKAQRTQTQLDLLTEENTKLNDELSNLRKELQRFRKKP 265

Query: 914  HQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIEN 973
             Q       K  +  E+    Q  S I D+K  N++  K I  ++QLE +  +    ++ 
Sbjct: 266  SQPQNSSPNKSDKKNELNQIKQRLSVIEDEKEKNQEQFKKI--LSQLEYENSQLIEKVQQ 323

Query: 974  LNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYIN-EINKLNAL--LKQKDEEIIALNQ 1030
            L    E+L    L   ++ V   QT    +++   N + +K N +  LK  +E+   L  
Sbjct: 324  LQQQNEQLQLKALNA-EQVVSAYQTDKMVFSKAVNNLKSDKENTVQTLKSLEEDNQKLRF 382

Query: 1031 KINNAQVSYMSMVSDYESKLAQ---FTTKLENMEEEMQRVSKQLLDSKQHNEELQILVRE 1087
            ++N          S+Y+    +   +    + + +E +R  + +   +Q   +L+   RE
Sbjct: 383  QLNEMDDQLQIQKSEYQQLQREKELYDRNYKKLNDEYEREKEFVQQLRQDKRDLE---RE 439

Query: 1088 QDDQIKELKETKLTFE-MNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQE 1146
             D + + ++E K+ FE M++ K     + S ++    +  N              L +  
Sbjct: 440  LDQEKQVIRELKVEFERMDVSKQN---LDSLLQKFKQEQKNQQQSQQHNPNQGQQLMM-- 494

Query: 1147 EEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQL 1206
             ++  +E  +L ++       ++    ++ + +  N EL     +  +Q+++L  K   L
Sbjct: 495  -DQLRKENDLLTKEVQTTEGLIKSIKRELGEKDRDNYELKQQKRLLNDQLSELAQKNANL 553

Query: 1207 NTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFES 1266
            +++    L  +A+L   +     ++  ++    +  L Q++    +T  EL++      S
Sbjct: 554  DSQIKLKLQDIAQLEQEVEQYKREQS-KMRLNQQSILEQKQKIENETVGELKLLQQQNNS 612

Query: 1267 KYEQLLD-SVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVIN-QIEILR 1324
               Q+ D  + +S  EE  KI   +++ + Q    DK +   NL+++  +    Q  +LR
Sbjct: 613  LKLQISDLGIFNSQLEEKLKIA--QELLNEQRLENDKLQ--MNLRQQSDETFKYQQNVLR 668

Query: 1325 SEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQ-LKKSSXX 1383
            ++ + E   +                 +  E    + ++ +S++N   +  + L K    
Sbjct: 669  NK-DKEMDYYNLTHEIERLRDQERKILIEKERFQSENLKLESVINQQTKQMEFLNKLKEE 727

Query: 1384 XXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVE 1443
                       +N  +       H+++    ++ +K + Y ++L   N   E +++++  
Sbjct: 728  AMKEARELRQMINGLKTN----DHEIKNTSIKLSEKVNNYEMSLQDIN---EQLQKEISR 780

Query: 1444 YEKRIEDLTYEKESELAILRLKMHENANHYETMQ---KESEIERVKLIEELNVKITESVS 1500
              K   +LT E +S+++ L+L+  +  N    ++   +  E ++ +L++ L  K +  + 
Sbjct: 781  SNKLYNELT-ESQSQISSLKLQKTDYENQIRQLKLLCESLEKQKEELLQRLQQKNSTKIE 839

Query: 1501 LNKQVA---ELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKH 1557
              +QV    ELN+ LE++V + +E    L+    ++    DE+ N  + VR ++  +Q+ 
Sbjct: 840  DERQVLQLRELNENLEDKVNQYSEQNIQLKRSLEQLDLERDEVQNQLDEVRETNISLQQQ 899

Query: 1558 VSFASDTKQGRDEQLDNTMNK 1578
            +   ++  Q +  +L     K
Sbjct: 900  IKQMNNEIQKQQSKLSEVSTK 920



 Score = 70.5 bits (165), Expect = 4e-10
 Identities = 146/708 (20%), Positives = 295/708 (41%), Gaps = 69/708 (9%)

Query: 892  ESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYE 951
            ++T+   QL+      K    + + L++  KKE + +  E N    + I+ K+  + K  
Sbjct: 40   KTTEGFQQLKKQLEETKINAAKFEQLLLPLKKENQRIVNENNQLHMTMIQIKEECDTKEN 99

Query: 952  KNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQS--PDYTEQYIN 1009
            K    V  LE++  ++K  +   N N E+  K+  EL  K+ +   +QS  PD T + ++
Sbjct: 100  KWRSQVRMLESERNDWKFILGQKN-NAEK--KLQEELFKKNNENNYSQSNQPDKTLKLVD 156

Query: 1010 EINKLNALLKQ-------KDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEE 1062
            +I +L   L Q        D   + L +K  + +      + + E ++ +  +KL+    
Sbjct: 157  QIQELERKLLQVQQDSRDNDNSKVLLEEKCKHLEFQ----IENREKEILRLKSKLDIQGT 212

Query: 1063 EMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEM-NIPKTEGMIISSTIEPM 1121
             +++++++ + S+   +  +   + Q D + E + TKL  E+ N+ K          +P 
Sbjct: 213  NIEKLAQEHILSEAQQKAQR--TQTQLDLLTE-ENTKLNDELSNLRKELQRFRKKPSQPQ 269

Query: 1122 SDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKII-QLET 1180
            +   N  D             K  E  +  Q  SV++++  K     QE + KI+ QLE 
Sbjct: 270  NSSPNKSD-------------KKNELNQIKQRLSVIEDEKEKN----QEQFKKILSQLEY 312

Query: 1181 LNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWK 1240
             N++L       Q+Q  QL+  L+ LN E   ++S     +   S AV+    +  E   
Sbjct: 313  ENSQLIEKVQQLQQQNEQLQ--LKALNAEQ--VVSAYQTDKMVFSKAVNNLKSD-KENTV 367

Query: 1241 QHLAQREADFQKTEHELRV---QLSAFESKYEQLL--DSVQSSTQEETNKIVTMEQVTSL 1295
            Q L   E D QK   +L     QL   +S+Y+QL     +     ++ N     E+   +
Sbjct: 368  QTLKSLEEDNQKLRFQLNEMDDQLQIQKSEYQQLQREKELYDRNYKKLNDEYEREK-EFV 426

Query: 1296 QNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTE 1355
            Q   QDK +  R L ++   VI ++++   E E   V+                   +++
Sbjct: 427  QQLRQDKRDLERELDQE-KQVIRELKV---EFERMDVSKQNLDSLLQKFKQEQKNQQQSQ 482

Query: 1356 NQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSE 1415
              +  Q Q+  +  + +EN  L K               + + +    EL  Q  L + +
Sbjct: 483  QHNPNQGQQLMMDQLRKENDLLTKEVQTTEGLIKSIKRELGEKDRDNYELKQQKRLLNDQ 542

Query: 1416 IYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYET 1475
            + +        L Q+N   ++  +  ++   ++E    + + E + +RL         + 
Sbjct: 543  LSE--------LAQKNANLDSQIKLKLQDIAQLEQEVEQYKREQSKMRLNQQSILEQKQK 594

Query: 1476 MQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEM--QTALENQEIE- 1532
            ++ E+ +  +KL+++ N  +   +S    +   N  LEE++    E+  +  LEN +++ 
Sbjct: 595  IENET-VGELKLLQQQNNSLKLQIS---DLGIFNSQLEEKLKIAQELLNEQRLENDKLQM 650

Query: 1533 -IVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKE 1579
             +   +DE    Q  V  +  K   + +   + ++ RD++    + KE
Sbjct: 651  NLRQQSDETFKYQQNVLRNKDKEMDYYNLTHEIERLRDQERKILIEKE 698


>UniRef50_Q86KX8 Cluster: Similar to Dictyostelium discoideum (Slime
            mold). Interaptin; n=2; Dictyostelium discoideum|Rep:
            Similar to Dictyostelium discoideum (Slime mold).
            Interaptin - Dictyostelium discoideum (Slime mold)
          Length = 1781

 Score =  143 bits (346), Expect = 4e-32
 Identities = 281/1457 (19%), Positives = 617/1457 (42%), Gaps = 140/1457 (9%)

Query: 233  KDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQEL---EQXXXXXXXXX 289
            +DE + L K I+ K  +  +  +  K+ +    E+  E +K+  EL   E+         
Sbjct: 13   EDENEDLKKRIKQKAQQFDNQADVLKVTQKTATELKNEKNKILSELKLVEEKFNNGQIEI 72

Query: 290  XXXXXLAKQSI---EPSCEEKTEIE-EKGSLEIANMTEL-------TKKIEL-LEHLNCQ 337
                 + KQ+    +  CE   +++ EKG+LE  +  E+        K+IE+  E L   
Sbjct: 73   KKLQEILKQTKTNHQKVCELIDQLKVEKGNLEKQHQKEMREFEDKTNKQIEIQTEKLEKL 132

Query: 338  IRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQD 397
            I +T+K L    + +      + + +K+    + + +      KM+    QL  +  +  
Sbjct: 133  INETDK-LRCDKSNLEVRIVHLENSNKENKSYLLQSN--KEMGKMEIEIQQLQEQLTDSK 189

Query: 398  TDKKINKNEIAKLEMVIQSLN-------KDLVDKEYVIS---EKDTXXXXXXXXXXGKDT 447
              +   +++I   +++IQ L        K+L + ++  +   EK+              T
Sbjct: 190  EQESNQRSKIENKDIMIQQLRDKQQQYEKELRELQHQFNADNEKNQQIIDIQSEEISTST 249

Query: 448  LIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLK-QELNDEIKDVNVK--DLIEK 504
            LI   +LE +       L       ++ +EI  +  Q++  +L     D N +   LI +
Sbjct: 250  LI-MTELEEKLEFVSDKLKSEQEKLKE-SEILIMDLQIQVSDLQSTSDDDNERYQSLISE 307

Query: 505  LKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFS-KVSDSNKEIVRLTEE 563
             +   + ++QLN EI+   KN    ++  K  + ++ K  +++   +++ +K++  L  +
Sbjct: 308  YQENLKSVSQLNKEINEKLKNE---RTESKSLIDKISKENNDYQILITEQDKDLKDLKSQ 364

Query: 564  LHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKK-MIEMENLAETRLKAISLLESQ 622
            L   S   ++L ++   L L  ++Y+   +  +++  +  IE + L+    +    L+ Q
Sbjct: 365  LDTKSNNYSKLLDD---LSLSKLNYNKLNLEFNNISNEYQIEKQQLSFDFNELKKKLDDQ 421

Query: 623  KFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVI 682
                  +  +L Q+ +E+ DK  +I  L SD      K     +QI+ ++    +L + +
Sbjct: 422  IERNSNQQSLLTQRINEIIDKQKEIDNLNSDLQSLNDKQSDSNDQINTITNENNDLKIKL 481

Query: 683  ENL--------------KLDKEQLYGTIKDLENDKEDIMNKLQNYIQE-NMDLTDKLEKM 727
            EN               K + E LY  I++L +  +D + + +N I++  +D ++ L K 
Sbjct: 482  ENSILLISNHQDKLTTNKKELESLYSIIENLNSTHQDQLKEKENQIEQMKLDQSESLNKF 541

Query: 728  SAEKISEL---LAKINHEEQS------KIQTQFGIDAKI-QERDLYIENIESELSKYKSR 777
              EKI+ L   +  IN E+ S          Q     KI  +++   + + S + +    
Sbjct: 542  Q-EKITTLNHTIVNINSEKDSLNCLINDYSEQINELNKINNQKNQENQQLLSSIREDCQT 600

Query: 778  ICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVV 837
            I +L+ +I  ++D   SL  + + +   LQ  Q +      ++ EL N+   + +    V
Sbjct: 601  INQLKSTIKSLQDESNSLSTEIEAI--KLQLNQLSTITIPEKDQELSNKERTIQEFQ--V 656

Query: 838  EKQLLEIEHENKELQKKNQILLEENQNLQI-SLSD-MQQHYNALVEKANRTDLAESESTK 895
            + Q L+   +  +L     +   +NQ++ I SL++ + Q  +  ++K         +  +
Sbjct: 657  KTQQLKQTIQQNQLTINQHLTTIDNQSVDINSLNEKLVQLNDESIKKQQSIHSLSLQVIE 716

Query: 896  YQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIE 955
               +L + +    +       L  + + + +DL  +   Q++    D   L +K      
Sbjct: 717  LNKKLSEKDDQYNQSLESIDQLTSELQLKQDDLNRQ-QEQLQKNSIDIDQLFDKINLGKS 775

Query: 956  YVTQLEAQLQEYKNNIENLNMNVEE-LNKMN-LELIDKHVQKQQTQSPDYTEQYINEINK 1013
               +L  + Q  +N + NL  ++++ +N  N  +L    ++K   Q     E+  N   +
Sbjct: 776  NFDELNQRYQVEQNQLFNLKQDLQQSINLFNESKLYTTQLEKSIEQVKRVNEEQSNHQGE 835

Query: 1014 LNALLKQKDEEIIALNQKINNAQVSYMSMVSD---YESKLAQFTTKLENMEEEMQRVSKQ 1070
            L  LL ++  +   L   + N++    +   D   Y +++ Q   +L   +E +Q     
Sbjct: 836  LTILLDEERYKCQTLKMDLENSKQINQNQSDDLNFYNNQIEQLKQQLSESKELVQECKLS 895

Query: 1071 LLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMS--DDANNV 1128
            +   ++   ELQ+ ++E  ++ ++ +ET  +  + + K      +  +E +     +N++
Sbjct: 896  ISQFEKTVIELQLEIKELSNEKQQYQETCQSLSLKLSKLNDQ-SNDQLEQIQQLQSSNSL 954

Query: 1129 DXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKI-IQLETLNTELTG 1187
            D             ++   ++ + E S L+ Q      E  E  +K+ +++E    +LT 
Sbjct: 955  DLQNSQN-------QISLLQDSLNETSDLKSQLQCQLNESNEIISKLELKIEENQNQLTE 1007

Query: 1188 HDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQRE 1247
             ++  Q   +Q    L++   ++  L+             +D+   +I +L +Q L+  +
Sbjct: 1008 FELKIQSLSSQYNQDLQEQIEQSKMLIDEKQSCIQLQEMEIDKNNHKIQQL-QQDLSTSD 1066

Query: 1248 ADFQKTEHELRV---QLSAFESKYEQLLDSVQSS------TQEETNK-----IVTMEQVT 1293
               Q+ + +L++   ++   E    Q   S++ S       Q+ET+K     +     +T
Sbjct: 1067 YKIQQLQIDLQIDKDEIIKLEETISQRNQSIKESLVKCNDLQDETSKLNDNLLQLNSTIT 1126

Query: 1294 SLQNKLQDKEEHLRNLQEKYADV---INQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXX 1350
              Q+++ +  E++++LQ +   +   ++Q++   SE  D+                    
Sbjct: 1127 DYQSQITESNENVQSLQNEKNQLQLELDQLKQRISEQHDDITLLNSIEFELNRKISNYQS 1186

Query: 1351 DLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLE 1410
            D++  + + K +Q       NE+N QL+                V+   + +LEL  ++ 
Sbjct: 1187 DIKEYDNNIKVIQ-------NEKN-QLQLELDQLKQVLSDKQDGVSTLNSTLLELNKKIN 1238

Query: 1411 LKDSEIYQKTHEYTITLTQRND---EFENVRQQLVEYEKRIEDL--------TYEKESEL 1459
                EI      Y   + ++N    EF+ ++QQL E +  I  L        + +K S+ 
Sbjct: 1239 DYQMEINDSQSNYQELIDEKNQLQLEFDRLKQQLFEKQDEISTLKQDIQLFNSNKKNSDS 1298

Query: 1460 AILRLKMH----ENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEE 1515
            +I +L  H    ++ N    +   +E+ER KL  ++  ++ E+V L KQ +  N++  ++
Sbjct: 1299 SIDQLSNHVTELKSKNQQLLLDLSNELERNKLQNDMITQLKENVELEKQNSFENQSKSDD 1358

Query: 1516 V-AKTNEMQTALENQEIEIVTLN-DEITNLQNMVRASSSKIQKHVSF--ASDTKQGRDEQ 1571
            + +K +EM      QE + VT N  E TN  + ++    ++++ + F   S+T   ++  
Sbjct: 1359 IKSKLDEM-----IQEFKEVTQNLQEKTNENSNLQCKLDQLEQEIKFEKESNTHLRKEND 1413

Query: 1572 LDNTMNKELLDAVPRAE 1588
             D  + K+L  ++ + E
Sbjct: 1414 KDTLVIKQLEQSISQLE 1430



 Score =  138 bits (333), Expect = 2e-30
 Identities = 294/1540 (19%), Positives = 654/1540 (42%), Gaps = 168/1540 (10%)

Query: 144  VTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINE-KDQIIEAKNKATTXXXXXXXX 202
            + HL N+ KE  + L     +M  ME  I  LQE++ + K+Q    ++K           
Sbjct: 150  IVHLENSNKENKSYLLQSNKEMGKMEIEIQQLQEQLTDSKEQESNQRSKIEN-----KDI 204

Query: 203  XXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSL--EEANKLL 260
                     +  ++++ ++Q  F A      +EK + + DI+S+++  S+L   E  + L
Sbjct: 205  MIQQLRDKQQQYEKELRELQHQFNA-----DNEKNQQIIDIQSEEISTSTLIMTELEEKL 259

Query: 261  EAARFEISLEHSKLAQ-------------ELEQXXXXXXXXXXXXXXLAKQSIEPSCEEK 307
            E    ++  E  KL +             +L+                 +++++   +  
Sbjct: 260  EFVSDKLKSEQEKLKESEILIMDLQIQVSDLQSTSDDDNERYQSLISEYQENLKSVSQLN 319

Query: 308  TEIEEKGSLEIANMTELTKKIELLEH-LNCQIRQTNKELENKLATMGTESKAVS------ 360
             EI EK   E      L  KI    +     I + +K+L++  + + T+S   S      
Sbjct: 320  KEINEKLKNERTESKSLIDKISKENNDYQILITEQDKDLKDLKSQLDTKSNNYSKLLDDL 379

Query: 361  SPSKKGSPLISRKSGRNTASKMKSPWSQLSSE--TLNQDTDKKINKNEIAKLEMVIQSLN 418
            S SK     ++ +   N +++ +    QLS +   L +  D +I +N   +  ++ Q +N
Sbjct: 380  SLSKLNYNKLNLEF-NNISNEYQIEKQQLSFDFNELKKKLDDQIERNS-NQQSLLTQRIN 437

Query: 419  KDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQ---HMEGPSLI------HVG 469
             +++DK+  I   ++            +  I  +  E+      +E   L+       + 
Sbjct: 438  -EIIDKQKEIDNLNSDLQSLNDKQSDSNDQINTITNENNDLKIKLENSILLISNHQDKLT 496

Query: 470  TNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLK-SAEEQITQLNDEIDAANKNMIK 528
            TN +++  +  + E L     D++K+   ++ IE++K    E + +  ++I   N  ++ 
Sbjct: 497  TNKKELESLYSIIENLNSTHQDQLKE--KENQIEQMKLDQSESLNKFQEKITTLNHTIVN 554

Query: 529  V---KSNHKLKLKQMQKTIDNFSKVSD----SNKEIVRLTEE----LHHLSQKVAELEEE 577
            +   K +    +    + I+  +K+++     N++++    E    ++ L   +  L++E
Sbjct: 555  INSEKDSLNCLINDYSEQINELNKINNQKNQENQQLLSSIREDCQTINQLKSTIKSLQDE 614

Query: 578  KGNL--QLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQ 635
              +L  ++  +     ++    + +K  E+ N   T  +     +  K  + Q    + Q
Sbjct: 615  SNSLSTEIEAIKLQLNQLSTITIPEKDQELSNKERTIQEFQVKTQQLKQTIQQNQLTINQ 674

Query: 636  KYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGT 695
                ++++  DI+ L    V    +S+  ++ I +LS    EL   +        Q   +
Sbjct: 675  HLTTIDNQSVDINSLNEKLVQLNDESIKKQQSIHSLSLQVIELNKKLSEKDDQYNQSLES 734

Query: 696  IKDLEND---KEDIMNKLQNYIQEN-MDLTDKLEKMSAEK--ISELLAKINHEEQSKIQT 749
            I  L ++   K+D +N+ Q  +Q+N +D+    +K++  K    EL  +   E+      
Sbjct: 735  IDQLTSELQLKQDDLNRQQEQLQKNSIDIDQLFDKINLGKSNFDELNQRYQVEQNQLFNL 794

Query: 750  QFGIDAKI---QERDLYIENIESELSKYK----SRICRLEESIAVMEDRRYSLERKADQL 802
            +  +   I    E  LY   +E  + + K     +     E   ++++ RY  +     L
Sbjct: 795  KQDLQQSINLFNESKLYTTQLEKSIEQVKRVNEEQSNHQGELTILLDEERYKCQTLKMDL 854

Query: 803  GSYLQEKQKAYSE---YTIQEDELVNRLA---VLMDHDRV----VEKQLLEIEHENKELQ 852
             +  Q  Q    +   Y  Q ++L  +L+    L+   ++     EK ++E++ E KEL 
Sbjct: 855  ENSKQINQNQSDDLNFYNNQIEQLKQQLSESKELVQECKLSISQFEKTVIELQLEIKELS 914

Query: 853  KKNQILLEENQNLQISLSDMQQHYNALVEK------ANRTDLAESES--TKYQTQLR--- 901
             + Q   E  Q+L + LS +    N  +E+      +N  DL  S++  +  Q  L    
Sbjct: 915  NEKQQYQETCQSLSLKLSKLNDQSNDQLEQIQQLQSSNSLDLQNSQNQISLLQDSLNETS 974

Query: 902  DLESNLKRITHEHQTLIVQKKKEIEDLE---IEFNTQIES-AIRDKKVLNEKYEKNIEYV 957
            DL+S L+   +E   +I + + +IE+ +    EF  +I+S + +  + L E+ E++   +
Sbjct: 975  DLKSQLQCQLNESNEIISKLELKIEENQNQLTEFELKIQSLSSQYNQDLQEQIEQSKMLI 1034

Query: 958  TQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYI---NEINKL 1014
             + ++ +Q  +  I+  N  +++L + +L   D  +Q+ Q       ++ I     I++ 
Sbjct: 1035 DEKQSCIQLQEMEIDKNNHKIQQL-QQDLSTSDYKIQQLQIDLQIDKDEIIKLEETISQR 1093

Query: 1015 NALLKQ---KDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEE-------- 1063
            N  +K+   K  ++     K+N+  +   S ++DY+S++ +    +++++ E        
Sbjct: 1094 NQSIKESLVKCNDLQDETSKLNDNLLQLNSTITDYQSQITESNENVQSLQNEKNQLQLEL 1153

Query: 1064 ---MQRVSKQ-----LLDSKQH--NEEL---QILVREQDDQIKELKETKLTFEMNIPKTE 1110
                QR+S+Q     LL+S +   N ++   Q  ++E D+ IK ++  K   ++ + + +
Sbjct: 1154 DQLKQRISEQHDDITLLNSIEFELNRKISNYQSDIKEYDNNIKVIQNEKNQLQLELDQLK 1213

Query: 1111 GMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEE--EEFIQERSVLQEQSAKLNTEL 1168
              ++S   + +S   + +             +   +   +E I E++ LQ +  +L  +L
Sbjct: 1214 -QVLSDKQDGVSTLNSTLLELNKKINDYQMEINDSQSNYQELIDEKNQLQLEFDRLKQQL 1272

Query: 1169 QECYTKIIQLETLNTELTGHDVVNQE-QINQLKSKLEQLNTENDNLLSTVA-EL-RSSIS 1225
             E   +I  L+  + +L   +  N +  I+QL + + +L ++N  LL  ++ EL R+ + 
Sbjct: 1273 FEKQDEISTLKQ-DIQLFNSNKKNSDSSIDQLSNHVTELKSKNQQLLLDLSNELERNKLQ 1331

Query: 1226 SAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNK 1285
            + +  +  E  EL KQ+  +     Q    +++ +L     +++++  ++Q  T E +N 
Sbjct: 1332 NDMITQLKENVELEKQNSFEN----QSKSDDIKSKLDEMIQEFKEVTQNLQEKTNENSNL 1387

Query: 1286 IVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIE-----------DEKVAF 1334
               ++Q+       ++   HLR   +K   VI Q+E   S++E            E+   
Sbjct: 1388 QCKLDQLEQEIKFEKESNTHLRKENDKDTLVIKQLEQSISQLEHLHSQQTENYLKERELI 1447

Query: 1335 XXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXR 1394
                             L+++    +Q  ++S+  +++   +L K               
Sbjct: 1448 QQQHQDEKQSSIQSTHQLKSKFDEKQQQYDESLEKLSQSKQELNKLKQEFDLNILVIQKL 1507

Query: 1395 VNDAEAKV---LELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDL 1451
             +D +++    L+L   LE +  +  Q++ E   TL Q   +  +++QQ       I+ L
Sbjct: 1508 QDDKQSQSDSNLQLKSNLEEQQLQ-NQESIEKISTLQQ---QVNHLQQQFNINTLEIQKL 1563

Query: 1452 TYEKE---SELAILRLKMHENANHY-ETMQKESEIERVKLIEELNVKITESVSLNKQVAE 1507
              EK+     +  L+ K  E    Y E+++K ++++  K  ++L  K+  S + N+Q+ E
Sbjct: 1564 QDEKQLSIESIHQLKSKFDEKQQQYNESIEKSNDLQ--KQSDQLQQKLENSTNENQQLQE 1621

Query: 1508 LNKALEEE----VAKTNEMQTALENQEIEIVTLNDEITNL 1543
                ++ E    V + +     ++  +  ++  +DE+T L
Sbjct: 1622 KISTIQLEQINNVQQDDSKDLIIKQLQQSLLDKDDELTTL 1661



 Score =  134 bits (324), Expect = 2e-29
 Identities = 244/1138 (21%), Positives = 502/1138 (44%), Gaps = 138/1138 (12%)

Query: 312  EKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLIS 371
            EK SL    + + +++I  L  +N Q  Q N++L   L+++  + + ++        L  
Sbjct: 558  EKDSLNCL-INDYSEQINELNKINNQKNQENQQL---LSSIREDCQTINQLKSTIKSLQD 613

Query: 372  RKSGRNTASK-MKSPWSQLSSETLNQDTDKKINKNE-IAKLEMVIQSLNKDLVDKEYVIS 429
              +  +T  + +K   +QLS+ T+ +   +  NK   I + ++  Q L + +   +  I+
Sbjct: 614  ESNSLSTEIEAIKLQLNQLSTITIPEKDQELSNKERTIQEFQVKTQQLKQTIQQNQLTIN 673

Query: 430  EKDTXXXXXXXXXXGKDTLIAQLQ---LEHQQHMEGPSLIHVGTNT------EDVNEIAK 480
            +  T            +  + QL    ++ QQ +   SL  +  N       +  N+  +
Sbjct: 674  QHLTTIDNQSVDINSLNEKLVQLNDESIKKQQSIHSLSLQVIELNKKLSEKDDQYNQSLE 733

Query: 481  VQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNM------IKVKSNHK 534
              +QL  EL  +  D+N +   E+L+     I QL D+I+    N        +V+ N  
Sbjct: 734  SIDQLTSELQLKQDDLNRQQ--EQLQKNSIDIDQLFDKINLGKSNFDELNQRYQVEQNQL 791

Query: 535  LKLKQ-MQKTIDNFSK-------VSDSNKEIVRLTEEL-HHLSQKVAELEEEKGNLQLHL 585
              LKQ +Q++I+ F++       +  S +++ R+ EE  +H  +    L+EE+   Q   
Sbjct: 792  FNLKQDLQQSINLFNESKLYTTQLEKSIEQVKRVNEEQSNHQGELTILLDEERYKCQTLK 851

Query: 586  VDYDSGRMI---ESD---VYKKMIEM--ENLAETR------LKAISLLESQKFDL---VQ 628
            +D ++ + I   +SD    Y   IE   + L+E++        +IS  E    +L   ++
Sbjct: 852  MDLENSKQINQNQSDDLNFYNNQIEQLKQQLSESKELVQECKLSISQFEKTVIELQLEIK 911

Query: 629  ELHILQQKYDEVEDKLA-DISQL--QSDQVCSEIKSVHLEEQIDALSASKKELALVIENL 685
            EL   +Q+Y E    L+  +S+L  QS+    +I+ +     +D L  S+ +++L+ ++L
Sbjct: 912  ELSNEKQQYQETCQSLSLKLSKLNDQSNDQLEQIQQLQSSNSLD-LQNSQNQISLLQDSL 970

Query: 686  KLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMD-LTD---KLEKMSAEKISELLAKINH 741
              +   L   ++   N+  +I++KL+  I+EN + LT+   K++ +S++   +L  +I  
Sbjct: 971  N-ETSDLKSQLQCQLNESNEIISKLELKIEENQNQLTEFELKIQSLSSQYNQDLQEQIEQ 1029

Query: 742  ------EEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSL 795
                  E+QS IQ Q   + +I + +  I+ ++ +LS    +I +L+  + + +D    L
Sbjct: 1030 SKMLIDEKQSCIQLQ---EMEIDKNNHKIQQLQQDLSTSDYKIQQLQIDLQIDKDEIIKL 1086

Query: 796  ERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQ-KK 854
            E    Q    ++E     ++   +  +L + L  L       + Q+ E     + LQ +K
Sbjct: 1087 EETISQRNQSIKESLVKCNDLQDETSKLNDNLLQLNSTITDYQSQITESNENVQSLQNEK 1146

Query: 855  NQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEH 914
            NQ+ LE +Q L+  +S+  QH +  +  +   +L    S  YQ+ +++ ++N+K I +E 
Sbjct: 1147 NQLQLELDQ-LKQRISE--QHDDITLLNSIEFELNRKISN-YQSDIKEYDNNIKVIQNEK 1202

Query: 915  QTL---IVQKKKEIEDLE----------IEFNTQI---ESAIRD-----KKVLNEKYEKN 953
              L   + Q K+ + D +          +E N +I   +  I D     +++++EK +  
Sbjct: 1203 NQLQLELDQLKQVLSDKQDGVSTLNSTLLELNKKINDYQMEINDSQSNYQELIDEKNQLQ 1262

Query: 954  IEYVTQLEAQLQEYKNNIENLNMNVE--ELNKMN----LELIDKHVQKQQTQSPDYTEQY 1007
            +E+  +L+ QL E ++ I  L  +++    NK N    ++ +  HV + ++++       
Sbjct: 1263 LEF-DRLKQQLFEKQDEISTLKQDIQLFNSNKKNSDSSIDQLSNHVTELKSKNQQLLLDL 1321

Query: 1008 INEI--NKL-NALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEM 1064
             NE+  NKL N ++ Q  E +    Q     Q     + S  +  + +F    +N++E+ 
Sbjct: 1322 SNELERNKLQNDMITQLKENVELEKQNSFENQSKSDDIKSKLDEMIQEFKEVTQNLQEKT 1381

Query: 1065 QRVSK------QLLDSKQHNEELQILVREQDDQ----IKELKETKLTFE-MNIPKTEGMI 1113
               S       QL    +  +E    +R+++D+    IK+L+++    E ++  +TE  +
Sbjct: 1382 NENSNLQCKLDQLEQEIKFEKESNTHLRKENDKDTLVIKQLEQSISQLEHLHSQQTENYL 1441

Query: 1114 IS-STIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECY 1172
                 I+    D                  K Q+ +E +++ S  +++  KL  E     
Sbjct: 1442 KERELIQQQHQDEKQSSIQSTHQLKSKFDEKQQQYDESLEKLSQSKQELNKLKQEFDLNI 1501

Query: 1173 TKIIQLET-----------LNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELR 1221
              I +L+            L + L    + NQE I ++ +  +Q+N           E++
Sbjct: 1502 LVIQKLQDDKQSQSDSNLQLKSNLEEQQLQNQESIEKISTLQQQVNHLQQQFNINTLEIQ 1561

Query: 1222 S-------SISSAVDQRG-FEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLD 1273
                    SI S    +  F+  +       ++  D QK   +L+ +L    ++ +QL +
Sbjct: 1562 KLQDEKQLSIESIHQLKSKFDEKQQQYNESIEKSNDLQKQSDQLQQKLENSTNENQQLQE 1621

Query: 1274 SVQSSTQEETNKIVTMEQ----VTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEI 1327
             + +   E+ N +   +     +  LQ  L DK++ L  L E Y  +I + +I   +I
Sbjct: 1622 KISTIQLEQINNVQQDDSKDLIIKQLQQSLLDKDDELTTLFENYEQLIKKNKIDEKKI 1679



 Score =  101 bits (242), Expect = 2e-19
 Identities = 161/811 (19%), Positives = 337/811 (41%), Gaps = 56/811 (6%)

Query: 144  VTHLSNTIKEKDNALSVLQVKMKIMETTI-LDLQEKINEKDQIIEAKNKATTXXXXXXXX 202
            ++ L   I+E  N L+  ++K++ + +    DLQE+I +   +I+ K             
Sbjct: 991  ISKLELKIEENQNQLTEFELKIQSLSSQYNQDLQEQIEQSKMLIDEKQSCIQLQEMEIDK 1050

Query: 203  XXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRIS-SLEEANKLLE 261
                     +D      K+Q+  I ++ + KDE  +L + I  ++  I  SL + N L +
Sbjct: 1051 NNHKIQQLQQDLSTSDYKIQQLQIDLQID-KDEIIKLEETISQRNQSIKESLVKCNDLQD 1109

Query: 262  AARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANM 321
                    E SKL   L Q               + ++++    EK +++ +       +
Sbjct: 1110 --------ETSKLNDNLLQLNSTITDYQSQITE-SNENVQSLQNEKNQLQLELDQLKQRI 1160

Query: 322  TELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASK 381
            +E    I LL  +  ++ +     ++ +       K + +  +K    +     +   S 
Sbjct: 1161 SEQHDDITLLNSIEFELNRKISNYQSDIKEYDNNIKVIQN--EKNQLQLELDQLKQVLSD 1218

Query: 382  MKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVIS-EKDTXXXXXXX 440
             +   S L+S  L  + +KKIN  ++   +   QS  ++L+D++  +  E D        
Sbjct: 1219 KQDGVSTLNSTLL--ELNKKINDYQMEINDS--QSNYQELIDEKNQLQLEFDRLKQQLFE 1274

Query: 441  XXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKD 500
                  TL   +QL +       S I   +N   V E+    +QL  +L++E+       
Sbjct: 1275 KQDEISTLKQDIQLFNSNKKNSDSSIDQLSN--HVTELKSKNQQLLLDLSNEL------- 1325

Query: 501  LIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRL 560
              E+ K   + ITQL + ++   +N  + +S       ++ + I  F +V+ + +E    
Sbjct: 1326 --ERNKLQNDMITQLKENVELEKQNSFENQSKSDDIKSKLDEMIQEFKEVTQNLQE---K 1380

Query: 561  TEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLE 620
            T E  +L  K+ +LE+E         + +S   +  +  K  + ++ L ++  +   L  
Sbjct: 1381 TNENSNLQCKLDQLEQEIK------FEKESNTHLRKENDKDTLVIKQLEQSISQLEHLHS 1434

Query: 621  SQKFDLVQELHILQQKY-DEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELA 679
             Q  + ++E  ++QQ++ DE +  +    QL+S     + K    +E ++ LS SK+EL 
Sbjct: 1435 QQTENYLKERELIQQQHQDEKQSSIQSTHQLKSK---FDEKQQQYDESLEKLSQSKQEL- 1490

Query: 680  LVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKI 739
                 LK + +     I+ L++DK+   +     ++ N++      + S EKIS L  ++
Sbjct: 1491 ---NKLKQEFDLNILVIQKLQDDKQS-QSDSNLQLKSNLEEQQLQNQESIEKISTLQQQV 1546

Query: 740  NHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKA 799
            NH +Q        I     E+ L IE+I    SK+  +  +  ESI    D +   ++  
Sbjct: 1547 NHLQQQFNINTLEIQKLQDEKQLSIESIHQLKSKFDEKQQQYNESIEKSNDLQKQSDQLQ 1606

Query: 800  DQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVV---EKQLLEIEHENKELQKKNQ 856
             +L +   E Q+   + +  + E +N +      D ++   ++ LL+ + E   L +  +
Sbjct: 1607 QKLENSTNENQQLQEKISTIQLEQINNVQQDDSKDLIIKQLQQSLLDKDDELTTLFENYE 1666

Query: 857  ILLEENQNLQISLSDMQQHYNALVEKAN-----RTDLAESESTKYQTQLRDLESNLKRIT 911
             L+++N+  +  +  ++   N++    N     +  L E  ++K         S L+++ 
Sbjct: 1667 QLIKKNKIDEKKIRTLESKLNSINSTVNHNLPIKKPLEEVSNSKINIISSSSPSKLEQLQ 1726

Query: 912  HEHQTLIVQKKKEIEDLEIEFNTQIESAIRD 942
                    Q+K  I    ++   +I+   +D
Sbjct: 1727 TVSNQQSQQQKPTINKPPLQIKRKIDFNSQD 1757



 Score = 83.8 bits (198), Expect = 4e-14
 Identities = 145/695 (20%), Positives = 291/695 (41%), Gaps = 74/695 (10%)

Query: 900  LRDLESNLK-RITHEHQTLIVQKK--KEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEY 956
            L D   +LK RI  + Q    Q    K  +    E   +    + + K++ EK+      
Sbjct: 12   LEDENEDLKKRIKQKAQQFDNQADVLKVTQKTATELKNEKNKILSELKLVEEKFNNGQIE 71

Query: 957  VTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYIN-EINKLN 1015
            + +L+  L++ K N + +   +++L K+    ++K  QK+  +  D T + I  +  KL 
Sbjct: 72   IKKLQEILKQTKTNHQKVCELIDQL-KVEKGNLEKQHQKEMREFEDKTNKQIEIQTEKLE 130

Query: 1016 ALLKQKDEEIIALNQKINNAQVSYMSMV-SDYESK--LAQFTTKLENMEEEMQRVSKQLL 1072
             L+ + D+    L    +N +V  + +  S+ E+K  L Q   ++  ME E+Q++ +QL 
Sbjct: 131  KLINETDK----LRCDKSNLEVRIVHLENSNKENKSYLLQSNKEMGKMEIEIQQLQEQLT 186

Query: 1073 DSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXX 1132
            DSK+     +  +  +D  I++L++ +  +E  + + +    +        +   +D   
Sbjct: 187  DSKEQESNQRSKIENKDIMIQQLRDKQQQYEKELRELQHQFNADN----EKNQQIIDIQS 242

Query: 1133 XXXXXXXXXL-KVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVV 1191
                     + +++E+ EF+ ++  L+ +  KL     E     +Q++  + + T  D  
Sbjct: 243  EEISTSTLIMTELEEKLEFVSDK--LKSEQEKLKE--SEILIMDLQIQVSDLQSTSDDDN 298

Query: 1192 NQEQ--INQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREAD 1249
             + Q  I++ +  L+ ++  N  +   +   R+   S +D+   E  + ++  + +++ D
Sbjct: 299  ERYQSLISEYQENLKSVSQLNKEINEKLKNERTESKSLIDKISKENND-YQILITEQDKD 357

Query: 1250 FQKTEHELRVQLSAFESKYEQLLDSVQSSTQE------ETNKIVTMEQV---------TS 1294
             +    +L+ QL    + Y +LLD +  S         E N I    Q+           
Sbjct: 358  LK----DLKSQLDTKSNNYSKLLDDLSLSKLNYNKLNLEFNNISNEYQIEKQQLSFDFNE 413

Query: 1295 LQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRT 1354
            L+ KL D+ E   N Q      IN+I   + EI D   +                  +  
Sbjct: 414  LKKKLDDQIERNSNQQSLLTQRINEIIDKQKEI-DNLNSDLQSLNDKQSDSNDQINTITN 472

Query: 1355 ENQSYKQMQEQSILNINEENAQL---KKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLEL 1411
            EN   K   E SIL I+    +L   KK                 D   +      Q++L
Sbjct: 473  ENNDLKIKLENSILLISNHQDKLTTNKKELESLYSIIENLNSTHQDQLKEKENQIEQMKL 532

Query: 1412 KDSEIYQKTHEYTITLTQR----NDEFENVRQQLVEYEKRIEDL-------TYEKESELA 1460
              SE   K  E   TL       N E +++   + +Y ++I +L         E +  L+
Sbjct: 533  DQSESLNKFQEKITTLNHTIVNINSEKDSLNCLINDYSEQINELNKINNQKNQENQQLLS 592

Query: 1461 ILR---LKMHENANHYETMQKES-----EIERVKLIEELNVKITESV-SLNKQVAELNKA 1511
             +R     +++  +  +++Q ES     EIE +KL  +LN   T ++   +++++   + 
Sbjct: 593  SIREDCQTINQLKSTIKSLQDESNSLSTEIEAIKL--QLNQLSTITIPEKDQELSNKERT 650

Query: 1512 LEEEVAKTNEM-QTALENQEIEIVTLNDEITNLQN 1545
            ++E   KT ++ QT  +NQ    +T+N  +T + N
Sbjct: 651  IQEFQVKTQQLKQTIQQNQ----LTINQHLTTIDN 681


>UniRef50_A0DQ77 Cluster: Chromosome undetermined scaffold_6, whole
            genome shotgun sequence; n=2; Paramecium tetraurelia|Rep:
            Chromosome undetermined scaffold_6, whole genome shotgun
            sequence - Paramecium tetraurelia
          Length = 3126

 Score =  143 bits (346), Expect = 4e-32
 Identities = 296/1477 (20%), Positives = 626/1477 (42%), Gaps = 175/1477 (11%)

Query: 174  DLQEKINE---KDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEA 230
            DLQ+++NE   ++  + AK K                     + ++Q+ +  + +  +  
Sbjct: 940  DLQKQLNELQKQNAELLAKLKTQKDTQMQYMSKLSQSSENLTNYEKQLQQQTQKYAELNQ 999

Query: 231  EWKDEKQR---LLKD-IESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXX 286
            E+   KQ+   L K+  +SK  +   + +  + +   + +++    +L +++ Q      
Sbjct: 1000 EYIQFKQKYDQLQKESTQSKSAQSKEINQYQQKITQLQQQMNETSKQLKEKVNQLQSQLL 1059

Query: 287  XXXXXXXXLAKQSIE---PSCEEKT---EIEEKGSLEIANMTELTKKI-ELLEHLNCQIR 339
                    L KQ        C +KT   EI+ + +     + E  +++ E+   LN +I 
Sbjct: 1060 LEQEQCQILKKQQENFQRDFCMQKTQNGEIQNQTNTLRQQLIEKEQQLKEVQTILNTKI- 1118

Query: 340  QTNKELENKLATMGTE----SKAVSSPSKKGSPLISRKSGRNTA--SKMKSPWSQLSSET 393
            Q  ++LEN++  +  +    SK V S ++     + ++  ++    +++    S L  + 
Sbjct: 1119 QVIQQLENQVKDVQVQNASTSKQVQSLNQIQVDNLKKQLQQDQLRINELNDQISNLQQKI 1178

Query: 394  LNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQ 453
               +   +  K    K+   IQS  K L+  +Y                  K  L  QLQ
Sbjct: 1179 FTLEQQLQAEKQNNIKITKEIQS-TKILIQNDYQQQTHQLEQENIDLQQKLKQ-LEQQLQ 1236

Query: 454  LEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQIT 513
             E + +++         N   VN++   QE      N++I + N+K  IE+LK   E ++
Sbjct: 1237 KERENNIQIQQQFITIENNYQVNQVKSTQE------NEKIVN-NLKFQIEQLKLQNEDLS 1289

Query: 514  QLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAE 573
                        +IKV+SN+++++  M         V +  K+++   E+  + S ++ +
Sbjct: 1290 S----------QIIKVRSNYEIQMSTMNTMTSQ--NVINLEKQLLFEKEQKENSSMRILQ 1337

Query: 574  LEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHIL 633
            LE++  + Q H++  D     E  +    +E +NL  ++ + I LL  Q+ D  +E+ IL
Sbjct: 1338 LEKQVADFQ-HIIKSDQTE--EYKIQLNQLENQNLKLSKERDILLLSKQRGD--EEIKIL 1392

Query: 634  QQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLY 693
              +  E+ ++    ++L+   + S  K  +  EQI  ++   ++  ++ +  +    ++ 
Sbjct: 1393 NVRISELSNQNTQ-NELELMNLRS--KQGNQMEQISKMTTLTQQTVILQQERQSQNNEMI 1449

Query: 694  GTIKDLENDKEDIMNKLQNY-IQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFG 752
               + +E + +D   ++    I  + DL ++   ++ +   E+L   N  +  + + +F 
Sbjct: 1450 LMRQRMEKNIQDHEQQIAELRISFSRDLENQ-NMLNRKLQDEILNAQNLLQSERREREF- 1507

Query: 753  IDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKA 812
                +Q+   + E +  +L++ K     L + I  +  +   L+ + ++LG     +Q +
Sbjct: 1508 ----LQKSQSHSEQVIQQLNQDKQT---LHDQILKLNSQIQQLQMEINKLGF---NQQNS 1557

Query: 813  YSEYTIQEDELVNRLAVLMDHDRVVEKQL-LEIEHENKELQKKNQIL--LE-ENQNLQIS 868
              E+ + + ++ +     +DH  +  ++L  EI+  N ++Q+ N +   LE +NQNL+  
Sbjct: 1558 KDEHNLFQQQITS-YTTQIDHLNINTQKLNKEIDRLNLQIQQMNVMQGDLECQNQNLKQQ 1616

Query: 869  LSDMQQHYNALVEKANRTDLAESESTKYQT--QLRDLESNLK----------RITHEHQT 916
            LS +    N  +++ +  ++ E  S  Y +  Q++DL   L+          R    +  
Sbjct: 1617 LSLLTSQ-NQTIQQQSEINVIEIRSAAYDSEDQIQDLTQKLEQQIKETEKYQRAAFNNDQ 1675

Query: 917  LIVQKKKEIED-------LEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKN 969
            L+   +K+I D       ++ ++  QIE  IR K    EK++ +     Q+  Q+Q    
Sbjct: 1676 LVQSLQKKISDENLQNQKIKQQYEIQIEELIR-KINEKEKFDSSTPPKAQIFPQIQNTHL 1734

Query: 970  NIEN--LNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNAL---------- 1017
              EN  L + +++  KM +  + +   KQQ +    T++Y N  N+              
Sbjct: 1735 IQENEELLLKIDQYEKM-IRALQEEYYKQQGELQKLTKEYHNVTNQSEQTVVTITQYQQQ 1793

Query: 1018 ---LKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQR-VSKQLLD 1073
               +K+K++    L Q+I + Q  + +  S Y+ ++ + TTK + +  ++Q  ++KQ+++
Sbjct: 1794 QDNIKKKEDLTKQLQQQIQDLQKKFETERSRYQDEINRLTTKNQELSNQLQNNLNKQIIE 1853

Query: 1074 SKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXX 1133
             +  N + QI + EQ+ Q   +KET              II  +  P+    N  +    
Sbjct: 1854 -ENFNLKNQIQLLEQELQNTPIKET--------------IIYQSASPLKK--NEEEITKY 1896

Query: 1134 XXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQ 1193
                    L++ +      + ++L++Q+     +L++   +I QL+ L  +L   +   Q
Sbjct: 1897 KQQANQLQLRMNQ---MASDYNLLEQQTELEKVQLEK---QIKQLQDLEQKLLNENNQQQ 1950

Query: 1194 EQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKT 1253
             QI  L+ +L+QL     N +S   EL   +     Q  FEI +L           +++ 
Sbjct: 1951 RQIEALQRQLQQLQMNRQNDMSQ--ELEFELKKLKSQ--FEITQL----------QYKQI 1996

Query: 1254 EHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKY 1313
            + EL +Q  +   +Y   L   Q+   E   +I+  EQ+ S + K Q+  E         
Sbjct: 1997 QEEL-IQAKSQAFQYRDELVDEQNQKNELNLRIIHYEQILS-ELKQQNNPE--------- 2045

Query: 1314 ADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQ---MQEQSILNI 1370
            + +I +  I++ +++D   A                  L+     Y Q   +Q+  I ++
Sbjct: 2046 STMIKETTIIKEQVQDP--ALIKQVNQLIDDNNSLRKQLQNLEADYIQKFRLQQLQIQDL 2103

Query: 1371 NEENAQLKKSSXXXXXXXXXXXXRV--NDAEAKVLELTHQLELKDSEIYQKTHEYTITLT 1428
            N +  Q  + +                ND  A++ +L  +      E+ ++   Y   + 
Sbjct: 2104 NNKINQNDEENYQKTTITEETTINTVSNDQSAEIRKLKDEKLFLQQELQKQQQLYKKQIE 2163

Query: 1429 QRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHEN---ANHYETMQKESEIERV 1485
            Q  +++E   QQ   Y+  I+ L   KE +    +  + EN   A   + +Q E  I R 
Sbjct: 2164 QITNDYEFRIQQ---YKLTIQQLKESKEIQTNDDQNLLKENQMLAEQIKHLQNELTISRA 2220

Query: 1486 KLIEELNVKITESVSLNK--QVAELNKALEEEVAKTNEM----QTALENQEIEIVTLNDE 1539
               ++L      S   NK   + + N+ L++++ + N++    Q  L+N +I       E
Sbjct: 2221 SFQDQLQQNNQNSTEANKLKSLQKRNEDLDQQIEQQNKIIAQFQQQLQNIQIIYEEKEKE 2280

Query: 1540 ITNLQNMVRASSSKIQKHVSFASDTKQGR--DEQLDN 1574
            + NL+   +  +S++ K    +    Q R  +EQL N
Sbjct: 2281 LQNLKTNYQNLNSQLNKAPQLSEPENQSRIHNEQLIN 2317



 Score =  133 bits (321), Expect = 4e-29
 Identities = 268/1417 (18%), Positives = 588/1417 (41%), Gaps = 105/1417 (7%)

Query: 220  KMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEE----ANKLLEAARFE---ISLEHS 272
            +M++N    E +  + +    +D+E++++    L++    A  LL++ R E   +    S
Sbjct: 1454 RMEKNIQDHEQQIAELRISFSRDLENQNMLNRKLQDEILNAQNLLQSERREREFLQKSQS 1513

Query: 273  KLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCE-EKTEIEEKGSLEIANM--TELTKKIE 329
               Q ++Q              L  Q  +   E  K    ++ S +  N+   ++T    
Sbjct: 1514 HSEQVIQQLNQDKQTLHDQILKLNSQIQQLQMEINKLGFNQQNSKDEHNLFQQQITSYTT 1573

Query: 330  LLEHLNCQIRQTNKELEN---KLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPW 386
             ++HLN   ++ NKE++    ++  M      +   ++     +S  + +N   + +S  
Sbjct: 1574 QIDHLNINTQKLNKEIDRLNLQIQQMNVMQGDLECQNQNLKQQLSLLTSQNQTIQQQSEI 1633

Query: 387  SQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKD 446
            + +   +   D++ +I ++   KLE  I+   K      Y  +  +             D
Sbjct: 1634 NVIEIRSAAYDSEDQI-QDLTQKLEQQIKETEK------YQRAAFNNDQLVQSLQKKISD 1686

Query: 447  TLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLK 506
              +   +++ Q  ++   LI      E  +     + Q+  ++ +       ++L+ K+ 
Sbjct: 1687 ENLQNQKIKQQYEIQIEELIRKINEKEKFDSSTPPKAQIFPQIQNTHLIQENEELLLKID 1746

Query: 507  SAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHH 566
              E+ I  L +E       + K+   +     Q ++T+   ++       I +  +    
Sbjct: 1747 QYEKMIRALQEEYYKQQGELQKLTKEYHNVTNQSEQTVVTITQYQQQQDNIKKKEDLTKQ 1806

Query: 567  LSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDL 626
            L Q++ +L+++    +    D +  R+       K  E+ N  +  L    ++E + F+L
Sbjct: 1807 LQQQIQDLQKKFETERSRYQD-EINRLTT-----KNQELSNQLQNNLNK-QIIE-ENFNL 1858

Query: 627  VQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELA----LVI 682
              ++ +L+Q+      K   I Q  S    +E +    ++Q + L     ++A    L+ 
Sbjct: 1859 KNQIQLLEQELQNTPIKETIIYQSASPLKKNEEEITKYKQQANQLQLRMNQMASDYNLLE 1918

Query: 683  ENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHE 742
            +  +L+K QL   IK L++ ++ ++N+     ++   L  +L+++   + +++  ++  E
Sbjct: 1919 QQTELEKVQLEKQIKQLQDLEQKLLNENNQQQRQIEALQRQLQQLQMNRQNDMSQELEFE 1978

Query: 743  EQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQL 802
             + K+++QF I        L  + I+ EL + KS+  +  + +   ++++  L  +    
Sbjct: 1979 LK-KLKSQFEIT------QLQYKQIQEELIQAKSQAFQYRDELVDEQNQKNELNLRIIHY 2031

Query: 803  GSYLQE-KQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQIL--- 858
               L E KQ+   E T+ ++  + +  V    D  + KQ+ ++  +N  L+K+ Q L   
Sbjct: 2032 EQILSELKQQNNPESTMIKETTIIKEQV---QDPALIKQVNQLIDDNNSLRKQLQNLEAD 2088

Query: 859  -LEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTL 917
             +++ +  Q+ + D+    N   E+ N      +E T   T   D  + ++++  E   L
Sbjct: 2089 YIQKFRLQQLQIQDLNNKINQNDEE-NYQKTTITEETTINTVSNDQSAEIRKLKDEKLFL 2147

Query: 918  IVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQL-EAQLQEYKNNIENLNM 976
                ++E++  +  +  QIE    D +   ++Y+  I+ + +  E Q  + +N ++   M
Sbjct: 2148 ----QQELQKQQQLYKKQIEQITNDYEFRIQQYKLTIQQLKESKEIQTNDDQNLLKENQM 2203

Query: 977  NVEELNKMNLEL-IDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNA 1035
              E++  +  EL I +   + Q Q  +      N++  L    +  D++I   N+ I   
Sbjct: 2204 LAEQIKHLQNELTISRASFQDQLQQNNQNSTEANKLKSLQKRNEDLDQQIEQQNKIIAQF 2263

Query: 1036 QVSYMSMVSDYESK---LAQFTTKLENMEEEMQR---VSKQLLDSKQHNEELQILVREQD 1089
            Q    ++   YE K   L    T  +N+  ++ +   +S+    S+ HNE+L  L    D
Sbjct: 2264 QQQLQNIQIIYEEKEKELQNLKTNYQNLNSQLNKAPQLSEPENQSRIHNEQLINLQESVD 2323

Query: 1090 D---QIKELKETKLTFEMNIPKTEGMI--ISSTIEPMSDDANNVDXXXXXXXXXXXXLKV 1144
                QIK+ +E     +  I   E  I  +   IE +      ++            LK 
Sbjct: 2324 TLNLQIKQYREENNNLKKIIEDQEKEIQDLKLIIENLKHQITQLNLQNDELIQK---LKG 2380

Query: 1145 QEEEEFIQERSVLQEQSAKLNTEL-QECYTKIIQLETLNTE---LTGHDVVNQEQINQLK 1200
            QE+ + IQ +   Q  S+    +L Q+   K  +LE +N E   L    + NQ  I +L+
Sbjct: 2381 QEQVQ-IQLKENYQLSSSLDQGKLEQQLINKQFELEQINAENKKLNNKLIDNQNLIRKLQ 2439

Query: 1201 SKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQ 1260
             +L     E   L     + +S IS+  +Q      +L  Q   +R+++    + E+   
Sbjct: 2440 QELMTYGNEKQKLQ---LQYQSEISALQNQNKSMKQQLLDQQEIKRQSEQIPQKIEINQA 2496

Query: 1261 LSAFES-KYEQLLDSVQSS--TQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQ--EKYAD 1315
                 S K +Q   S+  S  +   T+ +       SL  K Q+ + +   L+  +  AD
Sbjct: 2497 HQTVNSPKPKQASKSLNRSDISFHSTDDLRGKYYNCSLYTKNQNGQNYFTPLRAVKSKAD 2556

Query: 1316 VINQIEILRSEIEDE---KVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINE 1372
            ++   EI ++  +DE   +V+                  + + N + KQ++E ++  I+ 
Sbjct: 2557 LLTTPEISQTNTQDELKKQVSLWQSKYEELLKDKYSKAYMYSPNLN-KQVEETTV-QIDV 2614

Query: 1373 ENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYT-----ITL 1427
             N + K                 N+   + L + +  EL  +++YQ   +Y      IT 
Sbjct: 2615 VNWKSKYEELQEQISNSNIKQGQNEKLIEQLRINN--ELLSTQLYQIQTDYQRIQTEITF 2672

Query: 1428 TQRNDEFENVRQQLVEYEKRIEDLTYE---KESELAILRLKMHENANHYETMQKESEIER 1484
            +Q++D    + Q  +  E+ IE L  +   +E+E+  LR K+ +     +   ++S  ++
Sbjct: 2673 SQKSD----LNQNNLNSERVIEQLNLKIKNQENEIEQLRQKLKQYVESKKNQDQKSNNKQ 2728

Query: 1485 VKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLN-DEITNL 1543
             + +++L    TE+    +++  L   ++    K N ++ ++ +QEI + +   D   N+
Sbjct: 2729 NEYLKQLE---TENFDYQQEIQSLRIEIKRLQEKNNLIKQSINDQEINLQSGQVDNEVNI 2785

Query: 1544 QNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKEL 1580
            +   +     +Q  ++   +       QL  +  KEL
Sbjct: 2786 EE-YQQQIEILQNEINIQQNQIYQLQNQLKQSKIKEL 2821



 Score =  124 bits (299), Expect = 2e-26
 Identities = 262/1320 (19%), Positives = 558/1320 (42%), Gaps = 149/1320 (11%)

Query: 306  EKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKK 365
            E+ + + +   E+    +L  + +  +     ++Q     ENKL+    E        K 
Sbjct: 835  EQAQQDNEKLKELYQQNDLNWQKQFQQKYTAALQQLQL-FENKLSLQNKEYNQNIEKQKV 893

Query: 366  GSPLISRKSG--RNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMV-----IQSLN 418
                + +K    + T  K +   +QL  +    D +KK  +NE  K ++      +Q  N
Sbjct: 894  NFNQLQQKFNDQKVTIDKQREEINQLKQQN-QDDKNKKPPQNEEIKDDLQKQLNELQKQN 952

Query: 419  KDLVDKEYVISEKDTXXXXXXXXXXGKDTLI---AQLQLEHQQHME-GPSLIHVGTNTED 474
             +L+ K  + ++KDT            + L     QLQ + Q++ E     I      + 
Sbjct: 953  AELLAK--LKTQKDTQMQYMSKLSQSSENLTNYEKQLQQQTQKYAELNQEYIQF---KQK 1007

Query: 475  VNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHK 534
             +++ K   Q K   + EI     K + +  +   E   QL ++++     ++  +   +
Sbjct: 1008 YDQLQKESTQSKSAQSKEINQYQQK-ITQLQQQMNETSKQLKEKVNQLQSQLLLEQEQCQ 1066

Query: 535  LKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHL-VDYDSGRM 593
            +  KQ +    +F      N EI   T  L    Q++ E E++   +Q  L       + 
Sbjct: 1067 ILKKQQENFQRDFCMQKTQNGEIQNQTNTLR---QQLIEKEQQLKEVQTILNTKIQVIQQ 1123

Query: 594  IESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSD 653
            +E+ V  K ++++N A T  +  SL + Q  +L ++L   Q + +E+ D+++++ Q    
Sbjct: 1124 LENQV--KDVQVQN-ASTSKQVQSLNQIQVDNLKKQLQQDQLRINELNDQISNLQQ---- 1176

Query: 654  QVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNY 713
                  K   LE+Q+ A    +K+      N+K+ KE +  T   ++ND +   ++L+  
Sbjct: 1177 ------KIFTLEQQLQA----EKQ-----NNIKITKE-IQSTKILIQNDYQQQTHQLE-- 1218

Query: 714  IQENMDLTDKLEKMSAEKISELLAKINHEEQS-KIQTQFGIDA--KIQERDLYIENIESE 770
             QEN+DL  KL+++  +   E    I  ++Q   I+  + ++     QE +  + N++ +
Sbjct: 1219 -QENIDLQQKLKQLEQQLQKERENNIQIQQQFITIENNYQVNQVKSTQENEKIVNNLKFQ 1277

Query: 771  LSKYK-------SRICRLEESIAV-MEDRRYSLERKADQLGSYL--QEKQKAYSEYTI-Q 819
            + + K       S+I ++  +  + M        +    L   L  +++QK  S   I Q
Sbjct: 1278 IEQLKLQNEDLSSQIIKVRSNYEIQMSTMNTMTSQNVINLEKQLLFEKEQKENSSMRILQ 1337

Query: 820  EDELVNRLAVLMDHDRVVEK--QLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYN 877
             ++ V     ++  D+  E   QL ++E++N +L K+  ILL   Q     +  +    +
Sbjct: 1338 LEKQVADFQHIIKSDQTEEYKIQLNQLENQNLKLSKERDILLLSKQRGDEEIKILNVRIS 1397

Query: 878  ALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLE-IEFNTQI 936
             L  +  + +L E  + + + Q   +E   K  T   QT+I+Q++++ ++ E I    ++
Sbjct: 1398 ELSNQNTQNEL-ELMNLRSK-QGNQMEQISKMTTLTQQTVILQQERQSQNNEMILMRQRM 1455

Query: 937  ESAIRDKKV----LNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKH 992
            E  I+D +     L   + +++E    L  +LQ+   N +NL +  E   +  L+    H
Sbjct: 1456 EKNIQDHEQQIAELRISFSRDLENQNMLNRKLQDEILNAQNL-LQSERREREFLQKSQSH 1514

Query: 993  VQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQ 1052
             ++   Q     +   ++I KLN+ ++Q   EI  L     N++  +    + ++ ++  
Sbjct: 1515 SEQVIQQLNQDKQTLHDQILKLNSQIQQLQMEINKLGFNQQNSKDEH----NLFQQQITS 1570

Query: 1053 FTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGM 1112
            +TT+++++    Q+++K++       +++ ++  + + Q + LK+     ++++  ++  
Sbjct: 1571 YTTQIDHLNINTQKLNKEIDRLNLQIQQMNVMQGDLECQNQNLKQ-----QLSLLTSQ-- 1623

Query: 1113 IISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECY 1172
              + TI+  S+  N ++                + E+ IQ+ +   EQ  K   + Q   
Sbjct: 1624 --NQTIQQQSE-INVIEIRSAAY----------DSEDQIQDLTQKLEQQIKETEKYQRAA 1670

Query: 1173 TKIIQL-ETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQR 1231
                QL ++L  +++  ++ NQ+   Q + ++E+L       +  + E +    S+   +
Sbjct: 1671 FNNDQLVQSLQKKISDENLQNQKIKQQYEIQIEEL-------IRKINE-KEKFDSSTPPK 1722

Query: 1232 GFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETN------- 1284
                 ++   HL Q   +      +    + A + +Y +    +Q  T+E  N       
Sbjct: 1723 AQIFPQIQNTHLIQENEELLLKIDQYEKMIRALQEEYYKQQGELQKLTKEYHNVTNQSEQ 1782

Query: 1285 KIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXX 1344
             +VT+ Q    Q+ ++ KE+  + LQ++  D+  + E  RS  +DE              
Sbjct: 1783 TVVTITQYQQQQDNIKKKEDLTKQLQQQIQDLQKKFETERSRYQDE-------------- 1828

Query: 1345 XXXXXXDLRTENQSY-KQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVL 1403
                   L T+NQ    Q+Q      I EEN  LK               +    E  + 
Sbjct: 1829 ----INRLTTKNQELSNQLQNNLNKQIIEENFNLKNQIQLLEQELQNTPIK----ETIIY 1880

Query: 1404 ELTHQLELKDSEI---YQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKE-SEL 1459
            +    L+  + EI    Q+ ++  + + Q   ++      L+E +  +E +  EK+  +L
Sbjct: 1881 QSASPLKKNEEEITKYKQQANQLQLRMNQMASDY-----NLLEQQTELEKVQLEKQIKQL 1935

Query: 1460 AILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKT 1519
              L  K+  N N+ +  Q E+ ++R     ++N +   S  L  ++ +L    E    + 
Sbjct: 1936 QDLEQKL-LNENNQQQRQIEA-LQRQLQQLQMNRQNDMSQELEFELKKLKSQFEITQLQY 1993

Query: 1520 NEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKE 1579
             ++Q  L   + +     DE+ + QN     + +I  +    S+ KQ  +   ++TM KE
Sbjct: 1994 KQIQEELIQAKSQAFQYRDELVDEQNQKNELNLRIIHYEQILSELKQQNNP--ESTMIKE 2051



 Score =  110 bits (265), Expect = 3e-22
 Identities = 248/1310 (18%), Positives = 538/1310 (41%), Gaps = 137/1310 (10%)

Query: 297  KQSIEPSCEEKTEIEEKGSLEIANMTELTKKIE-LLEHLNCQIRQTNKELENKLATMGTE 355
            KQ +     +   I+++  + +  +       E  ++ L  ++ Q  KE E         
Sbjct: 1614 KQQLSLLTSQNQTIQQQSEINVIEIRSAAYDSEDQIQDLTQKLEQQIKETEKYQRAAFNN 1673

Query: 356  SKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDK-KINKNEIAKLEMVI 414
             + V S  KK    IS ++ +N   K+K  +     E + +  +K K + +   K ++  
Sbjct: 1674 DQLVQSLQKK----ISDENLQN--QKIKQQYEIQIEELIRKINEKEKFDSSTPPKAQIFP 1727

Query: 415  QSLNKDLVDKE----YVISEKDTXXXXXXXXXXGKDTLIAQLQLE-HQQHMEGPSLIHVG 469
            Q  N  L+ +       I + +            +   + +L  E H    +    +   
Sbjct: 1728 QIQNTHLIQENEELLLKIDQYEKMIRALQEEYYKQQGELQKLTKEYHNVTNQSEQTVVTI 1787

Query: 470  TNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEE--QITQLNDEI-----DAA 522
            T  +   +  K +E L ++L  +I+D+  K   E+ +  +E  ++T  N E+     +  
Sbjct: 1788 TQYQQQQDNIKKKEDLTKQLQQQIQDLQKKFETERSRYQDEINRLTTKNQELSNQLQNNL 1847

Query: 523  NKNMIKVKSNHKLKLKQMQKTIDNF-----------SKVSDSNKEIVRLTEELHHLSQKV 571
            NK +I+   N K +++ +++ + N            S +  + +EI +  ++ + L  ++
Sbjct: 1848 NKQIIEENFNLKNQIQLLEQELQNTPIKETIIYQSASPLKKNEEEITKYKQQANQLQLRM 1907

Query: 572  AELEEEKGNL--QLHLVDYDSGRMIES--DVYKKMIEMENLAETRLKAIS-----LLESQ 622
             ++  +   L  Q  L      + I+   D+ +K++   N  + +++A+      L  ++
Sbjct: 1908 NQMASDYNLLEQQTELEKVQLEKQIKQLQDLEQKLLNENNQQQRQIEALQRQLQQLQMNR 1967

Query: 623  KFDLVQELHI-LQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALV 681
            + D+ QEL   L++   + E       Q+Q + + ++ ++    +++      K EL L 
Sbjct: 1968 QNDMSQELEFELKKLKSQFEITQLQYKQIQEELIQAKSQAFQYRDELVDEQNQKNELNLR 2027

Query: 682  IENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSA--EKISELLAKI 739
            I    +  EQ+   +K  +N+ E  M K    I+E +     +++++   +  + L  ++
Sbjct: 2028 I----IHYEQILSELKQ-QNNPESTMIKETTIIKEQVQDPALIKQVNQLIDDNNSLRKQL 2082

Query: 740  NHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESI-AVMEDRRYSLERK 798
             + E   IQ +F +  ++Q +DL  +  +++   Y+      E +I  V  D+   + + 
Sbjct: 2083 QNLEADYIQ-KFRLQ-QLQIQDLNNKINQNDEENYQKTTITEETTINTVSNDQSAEIRKL 2140

Query: 799  ADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKN-QI 857
             D+     QE QK    Y  Q +++ N     +   ++  +QL     E+KE+Q  + Q 
Sbjct: 2141 KDEKLFLQQELQKQQQLYKKQIEQITNDYEFRIQQYKLTIQQL----KESKEIQTNDDQN 2196

Query: 858  LLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTL 917
            LL+ENQ L   +  +Q      + +A+           +Q QL   + N +  T  ++  
Sbjct: 2197 LLKENQMLAEQIKHLQNELT--ISRAS-----------FQDQL---QQNNQNSTEANKLK 2240

Query: 918  IVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYV-TQLEAQLQEYKNNIENLNM 976
             +QK+ E  D +IE   +I +  + +        +NI+ +  + E +LQ  K N +NLN 
Sbjct: 2241 SLQKRNEDLDQQIEQQNKIIAQFQQQL-------QNIQIIYEEKEKELQNLKTNYQNLN- 2292

Query: 977  NVEELNKMNLELIDKHVQKQQTQSPDYTEQYIN---EINKLNALLKQKDEEIIALNQKIN 1033
               +LNK         + + + QS  + EQ IN    ++ LN  +KQ  EE        N
Sbjct: 2293 --SQLNKA------PQLSEPENQSRIHNEQLINLQESVDTLNLQIKQYREE--------N 2336

Query: 1034 NAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQ---LLDSKQHNEELQILVREQDD 1090
            N   +   ++ D E ++      +EN++ ++ +++ Q   L+   +  E++QI ++E   
Sbjct: 2337 N---NLKKIIEDQEKEIQDLKLIIENLKHQITQLNLQNDELIQKLKGQEQVQIQLKENYQ 2393

Query: 1091 QIKELKETKLTFEMNIPKTEGMIISSTIEPMSD---DANNVDXXXXXXXXXXXXLKVQEE 1147
                L + KL  ++   + E   I++  + +++   D  N+              K + +
Sbjct: 2394 LSSSLDQGKLEQQLINKQFELEQINAENKKLNNKLIDNQNLIRKLQQELMTYGNEKQKLQ 2453

Query: 1148 EEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELT---GHDVVNQEQINQLKSKLE 1204
             ++  E S LQ Q+  +  +L +      Q E +  ++     H  VN  +  Q    L 
Sbjct: 2454 LQYQSEISALQNQNKSMKQQLLDQQEIKRQSEQIPQKIEINQAHQTVNSPKPKQASKSLN 2513

Query: 1205 QLNTE---NDNLLSTVAELRSSISSAVDQRGFEIAELWKQH---LAQREADFQKTEHELR 1258
            + +      D+L            +   Q  F      K     L   E     T+ EL+
Sbjct: 2514 RSDISFHSTDDLRGKYYNCSLYTKNQNGQNYFTPLRAVKSKADLLTTPEISQTNTQDELK 2573

Query: 1259 VQLSAFESKYEQLLDSVQS-------STQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQE 1311
             Q+S ++SKYE+LL    S       +  ++  +      V + ++K ++ +E + N   
Sbjct: 2574 KQVSLWQSKYEELLKDKYSKAYMYSPNLNKQVEETTVQIDVVNWKSKYEELQEQISNSNI 2633

Query: 1312 KYADVINQIEILR--SEIEDEKV--AFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSI 1367
            K       IE LR  +E+   ++                    DL   N + +++ EQ  
Sbjct: 2634 KQGQNEKLIEQLRINNELLSTQLYQIQTDYQRIQTEITFSQKSDLNQNNLNSERVIEQLN 2693

Query: 1368 LNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITL 1427
            L I  +  ++++              +   +  K  E   QLE ++ +  Q+     I +
Sbjct: 2694 LKIKNQENEIEQLRQKLKQYVESKKNQDQKSNNKQNEYLKQLETENFDYQQEIQSLRIEI 2753

Query: 1428 TQRNDEFENVRQQLVEYEKRIE------DLTYEK-ESELAILRLKMHENANHYETMQKES 1480
             +  ++   ++Q + + E  ++      ++  E+ + ++ IL+ +++   N    +Q + 
Sbjct: 2754 KRLQEKNNLIKQSINDQEINLQSGQVDNEVNIEEYQQQIEILQNEINIQQNQIYQLQNQL 2813

Query: 1481 EIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQE 1530
            +  ++K + EL  K+  +V   +   EL +  +++     + Q   + Q+
Sbjct: 2814 KQSKIKEL-ELEQKLKYAVEDLEHAQELQQQQQQQQQYQQKQQQQQQQQQ 2862



 Score =  105 bits (252), Expect = 1e-20
 Identities = 234/1367 (17%), Positives = 552/1367 (40%), Gaps = 106/1367 (7%)

Query: 174  DLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWK 233
            DL +++ +  QI + + K  T                 E + Q    + +  I      K
Sbjct: 1802 DLTKQLQQ--QIQDLQKKFETERSRYQDEINRLTTKNQELSNQLQNNLNKQIIEENFNLK 1859

Query: 234  DEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXX 293
            ++ Q L +++++  ++ + + ++   L+    EI+    K  Q+  Q             
Sbjct: 1860 NQIQLLEQELQNTPIKETIIYQSASPLKKNEEEIT----KYKQQANQLQLRMNQMASDYN 1915

Query: 294  XLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMG 353
             L +Q+     + + +I++   LE   + E  ++   +E L  Q++Q     +N ++   
Sbjct: 1916 LLEQQTELEKVQLEKQIKQLQDLEQKLLNENNQQQRQIEALQRQLQQLQMNRQNDMS-QE 1974

Query: 354  TESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMV 413
             E +     S+     +  K  +    + KS   Q   E +++   K      I   E +
Sbjct: 1975 LEFELKKLKSQFEITQLQYKQIQEELIQAKSQAFQYRDELVDEQNQKNELNLRIIHYEQI 2034

Query: 414  IQSLNKD------LVDKEYVISEK---DTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPS 464
            +  L +       ++ +  +I E+                 ++L  QLQ     +++   
Sbjct: 2035 LSELKQQNNPESTMIKETTIIKEQVQDPALIKQVNQLIDDNNSLRKQLQNLEADYIQKFR 2094

Query: 465  L-------IHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQ-LN 516
            L       ++   N  D     K     +  +N    D + +  I KLK  +  + Q L 
Sbjct: 2095 LQQLQIQDLNNKINQNDEENYQKTTITEETTINTVSNDQSAE--IRKLKDEKLFLQQELQ 2152

Query: 517  DEIDAANKNMIKVKSNHKLKLKQMQKTIDNF--SKVSDSN------KEIVRLTEELHHLS 568
             +     K + ++ ++++ +++Q + TI     SK   +N      KE   L E++ HL 
Sbjct: 2153 KQQQLYKKQIEQITNDYEFRIQQYKLTIQQLKESKEIQTNDDQNLLKENQMLAEQIKHLQ 2212

Query: 569  QKVAELEEE-KGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLV 627
             ++       +  LQ +  +      ++S + K+  +++   E + K I+  + Q  ++ 
Sbjct: 2213 NELTISRASFQDQLQQNNQNSTEANKLKS-LQKRNEDLDQQIEQQNKIIAQFQQQLQNIQ 2271

Query: 628  -------QELHILQQKYDEVEDKLADISQLQSDQVCSEIKS---VHLEEQIDALSASKKE 677
                   +EL  L+  Y  +  +L    QL   +  S I +   ++L+E +D L+   K+
Sbjct: 2272 IIYEEKEKELQNLKTNYQNLNSQLNKAPQLSEPENQSRIHNEQLINLQESVDTLNLQIKQ 2331

Query: 678  LALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLA 737
                  NLK   E     I+DL+   E++ +++    Q N+   + ++K+  ++  ++  
Sbjct: 2332 YREENNNLKKIIEDQEKEIQDLKLIIENLKHQIT---QLNLQNDELIQKLKGQEQVQIQL 2388

Query: 738  KINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDR--RYSL 795
            K N++  S +  Q  ++ ++  +   +E I +E  K  +++   +  I  ++     Y  
Sbjct: 2389 KENYQLSSSLD-QGKLEQQLINKQFELEQINAENKKLNNKLIDNQNLIRKLQQELMTYGN 2447

Query: 796  ERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKN 855
            E++  QL  Y  E     ++    + +L+++  +    +++ +K  +   H+     K  
Sbjct: 2448 EKQKLQL-QYQSEISALQNQNKSMKQQLLDQQEIKRQSEQIPQKIEINQAHQTVNSPKPK 2506

Query: 856  QILLEENQN-LQI-SLSDMQ-QHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITH 912
            Q     N++ +   S  D++ ++YN  +   N+          Y T LR ++S    +T 
Sbjct: 2507 QASKSLNRSDISFHSTDDLRGKYYNCSLYTKNQN------GQNYFTPLRAVKSKADLLT- 2559

Query: 913  EHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIE 972
               T  + +    ++L+ + +       + +++L +KY K   Y   L  Q++E    I+
Sbjct: 2560 ---TPEISQTNTQDELKKQVSLWQS---KYEELLKDKYSKAYMYSPNLNKQVEETTVQID 2613

Query: 973  NLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKI 1032
             +N    +  ++  ++ + ++++ Q +      +  NE+  L+  L Q   +   +  +I
Sbjct: 2614 VVNWK-SKYEELQEQISNSNIKQGQNEKLIEQLRINNEL--LSTQLYQIQTDYQRIQTEI 2670

Query: 1033 NNAQVSYMSMVS-DYESKLAQFTTKLENMEEEMQRVS---KQLLDSKQHNEELQILVREQ 1088
              +Q S ++  + + E  + Q   K++N E E++++    KQ ++SK++ ++      +Q
Sbjct: 2671 TFSQKSDLNQNNLNSERVIEQLNLKIKNQENEIEQLRQKLKQYVESKKNQDQKSN--NKQ 2728

Query: 1089 DDQIKELKETKLTFEMNIP----KTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKV 1144
            ++ +K+L+     ++  I     + + +   + +   S +   ++             + 
Sbjct: 2729 NEYLKQLETENFDYQQEIQSLRIEIKRLQEKNNLIKQSINDQEINLQSGQVDNEVNIEEY 2788

Query: 1145 QEEEEFIQ-ERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKL 1203
            Q++ E +Q E ++ Q Q  +L  +L++   K ++LE    +    D+ + +++ Q + + 
Sbjct: 2789 QQQIEILQNEINIQQNQIYQLQNQLKQSKIKELELEQ-KLKYAVEDLEHAQELQQQQQQQ 2847

Query: 1204 EQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSA 1263
            +Q   +         + +        Q+   +   ++Q+       F     ++  +LS 
Sbjct: 2848 QQYQQKQQQQQQQQQQQQQQQQQPQQQQTQIVQTQYEQN-----NQFDDQYRQILYELSL 2902

Query: 1264 FESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYAD---VINQI 1320
             +S+   L   +Q ST+ +   +  ++++     +L      L N Q+K  D    +N++
Sbjct: 2903 IKSQNSSLQTQLQESTKTQVRLMQEIKELQIQNERLNISNVRLHNEQQKTTDQDNQVNRV 2962

Query: 1321 EILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSY-----KQMQEQSILNINEENA 1375
              L  E++ E                       ++ Q Y      ++++Q I ++  E A
Sbjct: 2963 NDLYKEVQIENQKLRSEISYLQQEKQQLISSFESKLQQYSASANSKIRQQQIEDLKRELA 3022

Query: 1376 QLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLE---LKDSEIYQKTHEYTITLTQRND 1432
            QLK+++                 +  + +L  QLE   +K+ E+ QK      + +Q   
Sbjct: 3023 QLKRATLKSSGVDIEAERLTYSTQ--ITQLKKQLEYEQIKNKELLQKLQ----SSSQYQS 3076

Query: 1433 EFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKE 1479
            +F  V +   E + +I +L   K      +++         E M+KE
Sbjct: 3077 DFGLVERLNKELQDKIVELHQVKSEYKNAIQMIHSLEEQVIERMEKE 3123



 Score =  100 bits (240), Expect = 3e-19
 Identities = 227/1124 (20%), Positives = 462/1124 (41%), Gaps = 142/1124 (12%)

Query: 455  EHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQ 514
            E Q+  + P  I    N  +  +    QEQ KQE   +    N KD ++  ++ E    Q
Sbjct: 697  EQQKEQQTPEQISKPQNPAE--QTKPKQEQPKQEEPQK----NPKDQVKNPQNPENLQKQ 750

Query: 515  LNDEIDAA-NKNMI-KVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVA 572
                 +   N +++ KV  N + + KQ  K ++N        K++V+  E L        
Sbjct: 751  PQKPQNVPQNPSVVNKVSQNPQFQNKQ-PKNLENL-------KQLVQQPESLRRSQPTSV 802

Query: 573  ELEEEKGNLQLHLVDYDSGRMI--ESDVYKKMIEMENLAETRLKAISLLESQKFDLVQEL 630
               ++K  + L   D +  R    E D  K ++E       +LK +     Q+ DL  + 
Sbjct: 803  RNSQDKKQIAL-AQDAEELRKQKQELDRLKNLLEQAQQDNEKLKELY----QQNDLNWQK 857

Query: 631  HILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKE 690
               QQKY       A + QLQ  +    +++    + I+    +  +L     + K+  +
Sbjct: 858  QF-QQKYT------AALQQLQLFENKLSLQNKEYNQNIEKQKVNFNQLQQKFNDQKVTID 910

Query: 691  QLYGTIKDLENDKEDIMNKLQNYIQE-NMDLTDKLEKMSAEKISELLAKINHEEQSKIQT 749
            +    I  L+   +D  NK     +E   DL  +L ++  +  +ELLAK+  ++ +++Q 
Sbjct: 911  KQREEINQLKQQNQDDKNKKPPQNEEIKDDLQKQLNELQKQN-AELLAKLKTQKDTQMQY 969

Query: 750  QFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEK 809
                 +K+ +    + N E +L +   +   L +            ++K DQL     + 
Sbjct: 970  M----SKLSQSSENLTNYEKQLQQQTQKYAELNQEY-------IQFKQKYDQLQKESTQS 1018

Query: 810  QKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISL 869
            + A S+   Q  + + +L   M+      KQL E     K  Q ++Q+LLE+ Q  QI L
Sbjct: 1019 KSAQSKEINQYQQKITQLQQQMNE---TSKQLKE-----KVNQLQSQLLLEQEQ-CQI-L 1068

Query: 870  SDMQQHY--NALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIED 927
               Q+++  +  ++K    ++    +T  Q QL + E  LK +    QT++  K + I+ 
Sbjct: 1069 KKQQENFQRDFCMQKTQNGEIQNQTNTLRQ-QLIEKEQQLKEV----QTILNTKIQVIQ- 1122

Query: 928  LEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLE 987
                   Q+E+ ++D +V N    K ++ + Q+  Q+   K  ++   + + ELN     
Sbjct: 1123 -------QLENQVKDVQVQNASTSKQVQSLNQI--QVDNLKKQLQQDQLRINELN----- 1168

Query: 988  LIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYE 1047
              D+    QQ            +I  L   L+ + +  I + ++I + ++    + +DY+
Sbjct: 1169 --DQISNLQQ------------KIFTLEQQLQAEKQNNIKITKEIQSTKI---LIQNDYQ 1211

Query: 1048 SKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEEL--QILVREQDDQIKELKETKLTFEMN 1105
             +  Q   +  +++++++++ +QL   +++N ++  Q +  E + Q+ ++K T+   E  
Sbjct: 1212 QQTHQLEQENIDLQQKLKQLEQQLQKERENNIQIQQQFITIENNYQVNQVKSTQEN-EKI 1270

Query: 1106 IPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQ-ERSVLQEQSAKL 1164
            +   +  I    ++   D ++ +             +     +  I  E+ +L E+  K 
Sbjct: 1271 VNNLKFQIEQLKLQ-NEDLSSQIIKVRSNYEIQMSTMNTMTSQNVINLEKQLLFEKEQKE 1329

Query: 1165 NTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNL-LSTVAELRSS 1223
            N+ +     +I+QLE    +     ++  +Q  + K +L QL  EN NL LS   ++   
Sbjct: 1330 NSSM-----RILQLEKQVADF--QHIIKSDQTEEYKIQLNQL--ENQNLKLSKERDILLL 1380

Query: 1224 ISSAVDQR----GFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDS---VQ 1276
                 D+        I+EL  Q+  Q E +      +   Q+    SK   L      +Q
Sbjct: 1381 SKQRGDEEIKILNVRISELSNQN-TQNELELMNLRSKQGNQMEQI-SKMTTLTQQTVILQ 1438

Query: 1277 SSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXX 1336
               Q + N+++ M Q   ++  +QD E+ +  L+  ++  +    +L  +++DE      
Sbjct: 1439 QERQSQNNEMILMRQ--RMEKNIQDHEQQIAELRISFSRDLENQNMLNRKLQDE-----I 1491

Query: 1337 XXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVN 1396
                          +   ++QS+    EQ I  +N++   L                 +N
Sbjct: 1492 LNAQNLLQSERREREFLQKSQSH---SEQVIQQLNQDKQTLHDQILKLNSQIQQLQMEIN 1548

Query: 1397 DAEAKVLELTHQLELKDSEIYQKTHE---YTITLTQRNDEFENVRQQLVEYEKRIEDLTY 1453
                       +  L   +I   T +     I   + N E + +  Q+ +      DL  
Sbjct: 1549 KLGFNQQNSKDEHNLFQQQITSYTTQIDHLNINTQKLNKEIDRLNLQIQQMNVMQGDLEC 1608

Query: 1454 EKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALE 1513
            + ++    L L   +N    +T+Q++SEI  +++        + +     Q+ +L + LE
Sbjct: 1609 QNQNLKQQLSLLTSQN----QTIQQQSEINVIEI-------RSAAYDSEDQIQDLTQKLE 1657

Query: 1514 EEVAKTNEMQTALENQEIEIVTLNDEIT--NLQNMVRASSSKIQ 1555
            +++ +T + Q A  N +  + +L  +I+  NLQN       +IQ
Sbjct: 1658 QQIKETEKYQRAAFNNDQLVQSLQKKISDENLQNQKIKQQYEIQ 1701



 Score = 74.1 bits (174), Expect = 3e-11
 Identities = 167/907 (18%), Positives = 381/907 (42%), Gaps = 76/907 (8%)

Query: 240  LKDIESKDVRISS-LEEANKLLEAARFEISLEHSKLAQELE----QXXXXXXXXXXXXXX 294
            LK ++ ++  +   +E+ NK++  A+F+  L++ ++  E +    Q              
Sbjct: 2239 LKSLQKRNEDLDQQIEQQNKII--AQFQQQLQNIQIIYEEKEKELQNLKTNYQNLNSQLN 2296

Query: 295  LAKQSIEPSCEEKTEIEEKGSL-EIANMTELTKKIELLEHLNCQ--IRQTNKELENKLAT 351
             A Q  EP  + +   E+  +L E  +   L  K    E+ N +  I    KE+++    
Sbjct: 2297 KAPQLSEPENQSRIHNEQLINLQESVDTLNLQIKQYREENNNLKKIIEDQEKEIQDLKLI 2356

Query: 352  MGTESKAVSSPSKKGSPLISRKSGRNTAS-KMKSPWSQLSSETLNQDTDKKINKN-EIAK 409
            +      ++  + +   LI +  G+     ++K  +   SS    +   + INK  E+ +
Sbjct: 2357 IENLKHQITQLNLQNDELIQKLKGQEQVQIQLKENYQLSSSLDQGKLEQQLINKQFELEQ 2416

Query: 410  LEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVG 469
            +    + LN  L+D + +I +             G +    +LQL++Q  +      +  
Sbjct: 2417 INAENKKLNNKLIDNQNLIRKLQQELMTY-----GNEK--QKLQLQYQSEISALQNQNKS 2469

Query: 470  TNTE--DVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMI 527
               +  D  EI +  EQ+ Q++  EI   +      K K A + + +   +I   + + +
Sbjct: 2470 MKQQLLDQQEIKRQSEQIPQKI--EINQAHQTVNSPKPKQASKSLNR--SDISFHSTDDL 2525

Query: 528  KVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVD 587
            + K  +     + Q   + F+ +     +   LT      +    EL+++    Q    +
Sbjct: 2526 RGKYYNCSLYTKNQNGQNYFTPLRAVKSKADLLTTPEISQTNTQDELKKQVSLWQSKYEE 2585

Query: 588  YDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQEL----HILQQKYDEVEDK 643
                +  ++ +Y   +  + + ET ++   +    K++ +QE     +I Q + +++ ++
Sbjct: 2586 LLKDKYSKAYMYSPNLNKQ-VEETTVQIDVVNWKSKYEELQEQISNSNIKQGQNEKLIEQ 2644

Query: 644  LADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDK 703
            L   ++L S Q+  +I++ +   Q +   + K +L     N +   EQL   IK+ EN+ 
Sbjct: 2645 LRINNELLSTQLY-QIQTDYQRIQTEITFSQKSDLNQNNLNSERVIEQLNLKIKNQENEI 2703

Query: 704  EDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLY 763
            E +  KL+ Y++   +   K      E + +L  + N + Q +IQ+      ++QE++  
Sbjct: 2704 EQLRQKLKQYVESKKNQDQKSNNKQNEYLKQLETE-NFDYQQEIQSLRIEIKRLQEKNNL 2762

Query: 764  IE--------NIES-------ELSKYKSRICRLEESIAVMEDRRYSLERKADQLG-SYLQ 807
            I+        N++S        + +Y+ +I  L+  I + +++ Y L+ +  Q     L+
Sbjct: 2763 IKQSINDQEINLQSGQVDNEVNIEEYQQQIEILQNEINIQQNQIYQLQNQLKQSKIKELE 2822

Query: 808  EKQKAYSEYTIQEDELVNRL-AVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQ 866
             +QK   +Y +++ E    L        +  +KQ  + + + ++ Q++ Q   ++ Q +Q
Sbjct: 2823 LEQKL--KYAVEDLEHAQELQQQQQQQQQYQQKQQQQQQQQQQQQQQQQQPQQQQTQIVQ 2880

Query: 867  ISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKK-EI 925
                   Q  +   +      L +S+++  QTQL++      R+  E + L +Q ++  I
Sbjct: 2881 TQYEQNNQFDDQYRQILYELSLIKSQNSSLQTQLQESTKTQVRLMQEIKELQIQNERLNI 2940

Query: 926  EDLEIEFNTQ-----------IESAIRDKKVLNEKYEKNIEYVTQ--------LEAQLQE 966
             ++ +    Q           +    ++ ++ N+K    I Y+ Q         E++LQ+
Sbjct: 2941 SNVRLHNEQQKTTDQDNQVNRVNDLYKEVQIENQKLRSEISYLQQEKQQLISSFESKLQQ 3000

Query: 967  YKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEII 1026
            Y  +  N  +  +++  +  EL        ++   D   + +    ++  L KQ + E I
Sbjct: 3001 YSAS-ANSKIRQQQIEDLKRELAQLKRATLKSSGVDIEAERLTYSTQITQLKKQLEYEQI 3059

Query: 1027 ALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQ--HNEELQIL 1084
               + +   Q S     SD+   + +   +L++   E+ +V  +  ++ Q  H+ E Q++
Sbjct: 3060 KNKELLQKLQ-SSSQYQSDF-GLVERLNKELQDKIVELHQVKSEYKNAIQMIHSLEEQVI 3117

Query: 1085 VREQDDQ 1091
             R + +Q
Sbjct: 3118 ERMEKEQ 3124



 Score = 46.8 bits (106), Expect = 0.005
 Identities = 43/169 (25%), Positives = 86/169 (50%), Gaps = 13/169 (7%)

Query: 914  HQTLIVQK---KKEIEDL-EIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKN 969
            H+ L+ +K   +K+++DL +     Q    I+DK    E+  K  + +T+L  Q+ + KN
Sbjct: 9    HKILLSKKDYYEKKMQDLIDRGIPNQYLLEIQDK----EQIAKQAQTITELNQQILQ-KN 63

Query: 970  NIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALN 1029
             +    +  +   +MNL LI + +     Q  +  E YI E+ K N +LKQ+ E+  +L 
Sbjct: 64   ALITQILQEKSQQEMNL-LISQQLFVINEQYKN-AEIYIQELQKENQILKQQFEDAPSLR 121

Query: 1030 QKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVS--KQLLDSKQ 1076
            QK+ N +  Y  ++ +   ++    T+  ++ +   +++   QLL+ K+
Sbjct: 122  QKLYNLEQWYAKLIHEKNQEIQLLKTQQPHIVQHAPQLNIINQLLEQKE 170


>UniRef50_UPI00006CC010 Cluster: hypothetical protein TTHERM_00411580;
            n=1; Tetrahymena thermophila SB210|Rep: hypothetical
            protein TTHERM_00411580 - Tetrahymena thermophila SB210
          Length = 3554

 Score =  142 bits (345), Expect = 5e-32
 Identities = 216/1109 (19%), Positives = 484/1109 (43%), Gaps = 107/1109 (9%)

Query: 467  HVGTNT--EDVNEIAKVQEQLKQELNDEIK-DVNVKDLIEKLKSAE-EQITQLNDEIDAA 522
            ++G+N   E   +  KV+   KQ+ N +++ D N   +    K+ E ++  Q  D+I+  
Sbjct: 2393 NLGSNQSIESTEDTEKVKRNKKQKQNKQVELDNNSNTVRSNSKNEEIQKYIQQQDQINNL 2452

Query: 523  NKNMIKVK------SNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHL--SQKVAEL 574
             K +++++        +++++K++ + I+     +   ++ ++L  ++  +  + +    
Sbjct: 2453 EKQILQLQIYESQDQQNQIRIKELNEKINQLQLQNLELEDKIKLKSKVDTMLSANQNQNQ 2512

Query: 575  EEEKGNLQLHLVDYDSGRMIESDVYKK--MIEMENLAETRLKAISLLESQKFDLVQ-ELH 631
            E+EK  + L +   +  ++I S   K+  +IE  +L +++LK +  L+ Q  +LV+ + +
Sbjct: 2513 EDEKKMIDLLVQIEELNKIINSQNSKEQQLIEENSLLKSQLKTLQDLQIQNEELVKFQKN 2572

Query: 632  ILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQ 691
             +++K   +ED+L D+ Q+  ++  S+ K+   E++I   +  K+        + L K Q
Sbjct: 2573 YIKEK-QIIEDRLKDLDQV-IEKNNSQYKNKIEEQRITIKNLEKR--------IDLFKSQ 2622

Query: 692  LYGTIKDLENDKED---IMNKLQNYIQENMDLTDKLEKMSAE----KISELLAKINHEEQ 744
                IKD  N ++D   I N    Y Q+   L ++LE +  +    ++     K+  E+Q
Sbjct: 2623 SVNNIKDKTNFEQDFYSIQNINAEYSQQVQKLKNELEVLQVKYKQLQVDNSQLKVQSEQQ 2682

Query: 745  SKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGS 804
            +K+ +Q        +++     ++ +L++  S++  LE  I          E+++D +  
Sbjct: 2683 NKVYSQ-------NKKEF--GELQFQLNQANSKVLLLENQIKQKIVADNDNEKQSDTIKG 2733

Query: 805  ---YLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEE 861
               +  E  K  +E+  Q+     +L +  + + +++  ++ ++   K + +K Q L  E
Sbjct: 2734 NDYFSSELIKLQAEFKNQD----KKLEIEKNQNLILQNNIINLQ---KIINQKQQELKNE 2786

Query: 862  NQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQK 921
             +      + ++Q+ N L+++        SE T+    L+ L++N  + T +     +++
Sbjct: 2787 KEESNTKFNLLEQNVNGLIQQNQSLKQQISEKTQ---SLQVLQNNYDQATKK-----LKE 2838

Query: 922  KKEIEDLEIEFNTQIESAIRDKKVLN-------EKYEKNIEYVTQLEAQLQEYKNNIENL 974
            K ++++L  +   Q+   I+D   L        E++ K ++    LE+Q+  YK  I  L
Sbjct: 2839 KMQVQELYEKQQNQLNQLIQDSACLQQELSRSKEEFNKKVQEQIDLESQIFNYKEQIFKL 2898

Query: 975  NMNVEEL-NKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNAL---LKQKDEEIIALNQ 1030
             + +++  + +N++ I       Q Q+   ++  +N+I ++N+    LKQ  + +I  N 
Sbjct: 2899 ELQLKKYQSNLNVDNISSASNTLQDQNDQRSQDLLNQIQRINSQNMQLKQSLDLVIEQNN 2958

Query: 1031 KINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDD 1090
            K+ +  +   + ++    ++ Q+   +  +E+E    +K+      H+  L++ +RE +D
Sbjct: 2959 KLADEVLLQKNQMNSMNQQILQYQQTISQLEDEQNEKTKKSKKIDMHSNNLELQIRELED 3018

Query: 1091 QIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEF 1150
            QI+   +  L   + +      I SS  + +S   N VD             KV++ E+ 
Sbjct: 3019 QIR--SKDLLVNSIQLELDNYRITSS--QKLSSIQNQVDEKTK---------KVEKLEQI 3065

Query: 1151 IQE-RSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTE 1209
             QE     Q+   +L+ + Q      IQ+  L  E     VVN   +N ++ +   LNT+
Sbjct: 3066 YQESEKNFQKHLVELSKKDQAIKNLQIQMSAL--ESKNLHVVN--DLNLIQQREATLNTQ 3121

Query: 1210 NDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYE 1269
               L+   ++LR+      D     ++ L K++   +E    K         + F  + +
Sbjct: 3122 VKQLVQENSQLRAQ-KIISDASQMNLSALIKENQILKEQHLTKIALIKYQVKNLFNHELK 3180

Query: 1270 QLLDSV-QSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYA-------DVINQIE 1321
            Q ++ V Q S Q+E     T++    LQ +LQ+++    +LQ  Y        + IN  E
Sbjct: 3181 QSIEKVKQISLQKEQQLHATIQ---ILQQQLQEEKSKYESLQTTYTSRNKKSQEHINADE 3237

Query: 1322 ILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSS 1381
            + +++I                        +  +N S K+  E+  + I +    L  S 
Sbjct: 3238 LKQNQIIISNKYQSTDLILDPQQIFSTLSQVVNDNTSLKKFIEEMSVKILQMQETLHNSL 3297

Query: 1382 XXXXXXXXXXXXRVNDAEAKVLELT---HQLELKDSEIYQKTHEYTITLTQRNDEFENVR 1438
                           D + +    +   HQ+E +  +I Q  ++  +   ++N    N+ 
Sbjct: 3298 ELLWKEQNVFMSCNLDTQEEQTNSSIQHHQIEKQVKQIIQNLNQLKMHKDEQNVSSGNLN 3357

Query: 1439 QQ---LVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKI 1495
             Q    +    +  +   E +       LK       Y   + E+ +++++ +E+ N K+
Sbjct: 3358 YQDSSSLPISLQAINKQQEDDGNNQSCLLKQITQFTQYTQQELENVVQQIEFLEKQN-KL 3416

Query: 1496 TESVSLNKQVAELNKALEEEVAKTNEMQT 1524
             ++   N Q       +E +V K   + T
Sbjct: 3417 LKNQLQNTQKENNKLLIELKVVKEQYINT 3445



 Score =  120 bits (288), Expect = 4e-25
 Identities = 225/1116 (20%), Positives = 484/1116 (43%), Gaps = 102/1116 (9%)

Query: 473  EDVNEIAKV---QEQLKQELNDEIKDVNVKDLI-EKLKSAEEQITQLNDEIDAANKNMIK 528
            +D N   KV   +EQ ++EL   I+D     L+ ++ +   +QIT+L+D++   ++++IK
Sbjct: 2143 KDENSSLKVKLQEEQQQKELLRNIQDNKQVPLLKQQAQQMIDQITKLSDQLKVKDQDLIK 2202

Query: 529  VKSN-HKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVD 587
             K+N  +++  Q  + I    K+ +S          L +   K A+ E EK N+ +   +
Sbjct: 2203 AKNNLLEIQYSQQNENIQLKQKLQESEL-------NLQYWKTKCADTEAEK-NMWISQYN 2254

Query: 588  YDSGRMIESD--VYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKL- 644
                  I  D  +    IE++N  +  LK    ++ QK + V  L IL     ++E+K+ 
Sbjct: 2255 QSVLNQIAQDKKIQDSKIEIDNQHKEYLKV--QIDEQKKE-VDSLKILNSNL-QLENKIL 2310

Query: 645  -ADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVI--ENL-KLDKEQLYGTIKDLE 700
               I+QL+      + KS   ++ + +L    ++L  ++  EN  KL K  +   + +LE
Sbjct: 2311 SEQINQLKESVTSFQYKSQFKDQYLGSLIRDLEQLNQIVRQENQEKLSKSNIEEQL-NLE 2369

Query: 701  NDKEDIMNKLQNYIQENMDLT-DKLEKMSAEKISELLAKINHEEQSKIQTQFGID----- 754
              + +I+ K    ++  +  T + L    + + +E   K+   ++ K   Q  +D     
Sbjct: 2370 QGRNEILRKHCQELELKIKTTQNNLGSNQSIESTEDTEKVKRNKKQKQNKQVELDNNSNT 2429

Query: 755  ----AKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLE-RKADQLGSYLQEK 809
                +K +E   YI+  + +++  + +I +L+  I   +D++  +  ++ ++  + LQ +
Sbjct: 2430 VRSNSKNEEIQKYIQQ-QDQINNLEKQILQLQ--IYESQDQQNQIRIKELNEKINQLQLQ 2486

Query: 810  QKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQK-------KNQILLEEN 862
                 +    + ++   L+   + ++  EK+++++  + +EL K       K Q L+EEN
Sbjct: 2487 NLELEDKIKLKSKVDTMLSANQNQNQEDEKKMIDLLVQIEELNKIINSQNSKEQQLIEEN 2546

Query: 863  QNLQISLSDMQ--QHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQ 920
              L+  L  +Q  Q  N  + K  +  + E +    + +L+DL+  +++   +++  I +
Sbjct: 2547 SLLKSQLKTLQDLQIQNEELVKFQKNYIKEKQI--IEDRLKDLDQVIEKNNSQYKNKIEE 2604

Query: 921  KKKEIEDLEIE---FNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMN 977
            ++  I++LE     F +Q  + I+DK    + +        +   Q+Q+ KN +E L + 
Sbjct: 2605 QRITIKNLEKRIDLFKSQSVNNIKDKTNFEQDFYSIQNINAEYSQQVQKLKNELEVLQVK 2664

Query: 978  VEELNKMNLELIDKHVQKQQTQSPDYTE----QY-INEIN-KLNALLKQKDEEIIALNQK 1031
             ++L   N +L  +  Q+ +  S +  E    Q+ +N+ N K+  L  Q  ++I+A N  
Sbjct: 2665 YKQLQVDNSQLKVQSEQQNKVYSQNKKEFGELQFQLNQANSKVLLLENQIKQKIVADND- 2723

Query: 1032 INNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQ 1091
             N  Q   +     + S+L +   + +N +++++    Q L  + +   LQ ++ ++  +
Sbjct: 2724 -NEKQSDTIKGNDYFSSELIKLQAEFKNQDKKLEIEKNQNLILQNNIINLQKIINQKQQE 2782

Query: 1092 IK-ELKETKLTFEMNIPKTEGMI--ISSTIEPMSDDANNVDXXXXXXXXXXXXL--KVQE 1146
            +K E +E+   F +      G+I    S  + +S+   ++             L  K+Q 
Sbjct: 2783 LKNEKEESNTKFNLLEQNVNGLIQQNQSLKQQISEKTQSLQVLQNNYDQATKKLKEKMQV 2842

Query: 1147 EEEFIQERSVLQ---EQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKL 1203
            +E + ++++ L    + SA L  EL     +  +      +L       +EQI +L+ +L
Sbjct: 2843 QELYEKQQNQLNQLIQDSACLQQELSRSKEEFNKKVQEQIDLESQIFNYKEQIFKLELQL 2902

Query: 1204 E--QLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREA------DFQKTEH 1255
            +  Q N   DN+ S    L+            +I  +  Q++  +++         K   
Sbjct: 2903 KKYQSNLNVDNISSASNTLQDQNDQRSQDLLNQIQRINSQNMQLKQSLDLVIEQNNKLAD 2962

Query: 1256 ELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYAD 1315
            E+ +Q +   S  +Q+L   Q+ +Q E  +    ++   +     + E  +R L+    D
Sbjct: 2963 EVLLQKNQMNSMNQQILQYQQTISQLEDEQNEKTKKSKKIDMHSNNLELQIRELE----D 3018

Query: 1316 VINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENA 1375
             I   ++L + I+ E   +                +   + +  +Q+ ++S  N  +   
Sbjct: 3019 QIRSKDLLVNSIQLELDNYRITSSQKLSSIQNQVDEKTKKVEKLEQIYQESEKNFQKHLV 3078

Query: 1376 QLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFE 1435
            +L K              +++  E+K L + + L L    I Q+       + Q   E  
Sbjct: 3079 ELSKKD----QAIKNLQIQMSALESKNLHVVNDLNL----IQQREATLNTQVKQLVQENS 3130

Query: 1436 NVRQQLV-------EYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLI 1488
             +R Q +            I++    KE  L  + L  ++  N +    K+S IE+VK  
Sbjct: 3131 QLRAQKIISDASQMNLSALIKENQILKEQHLTKIALIKYQVKNLFNHELKQS-IEKVK-- 3187

Query: 1489 EELNVKITESVSLNKQVAELNKALEEEVAKTNEMQT 1524
                + + +   L+  +  L + L+EE +K   +QT
Sbjct: 3188 ---QISLQKEQQLHATIQILQQQLQEEKSKYESLQT 3220



 Score =  105 bits (252), Expect = 1e-20
 Identities = 242/1238 (19%), Positives = 515/1238 (41%), Gaps = 106/1238 (8%)

Query: 387  SQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKD 446
            S   S+ L   T+  I   EI  ++  I   N    +  YV   K+              
Sbjct: 1881 SNNQSQVLLIQTESNIKDFEIKNIKEKILEENNSDNNSSYVHKYKEPNYSSAKKQ----- 1935

Query: 447  TLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQE-QLKQELN----DEIKDVNVKDL 501
              I QL  EH + +E  + +   TN    +    V+  QL+   N    +  +D  V D+
Sbjct: 1936 --IEQLN-EHVRTLEKQNQLLQSTNRNQSSTSLDVKNYQLESHSNFISPNSKQDRFVNDI 1992

Query: 502  IEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQ-KTIDNFSKVSDSNKEIVRL 560
            + + K     I QL D+I   N   I +K N      Q+Q K +   +++  +++ + + 
Sbjct: 1993 LYENKQLSISIKQLEDKIQ--NYRYIDIKYN------QLQTKVVLLANQLEQTSQFLEQR 2044

Query: 561  TEELHHLSQKVAELEEEKGNLQLHLVDYDS----GRMIESDVYKKMIEM-ENLAETRLK- 614
              E   L QK  +LE++  NLQ  L         GR I+ DV+++ ++  +++ +  L+ 
Sbjct: 2045 GFESQELKQKYFKLEQDYINLQKTLYSLKGQNTQGRSIQ-DVFEEQVKQYQSVEKQNLQY 2103

Query: 615  AISLLESQKFDLVQELHI--LQQKYDEVED-KLADISQLQSDQVCSEIKSVHLEEQIDAL 671
             I + E ++  L Q+  +  LQQKY+  E  +  ++  L+ +    ++K    ++Q + L
Sbjct: 2104 KIQIRELEELSLKQQEQLTQLQQKYNNQEQTQQINLKFLKDENSSLKVKLQEEQQQKELL 2163

Query: 672  S---------ASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTD 722
                        K++   +I+ +    +QL    +DL   K +++    +   EN+ L  
Sbjct: 2164 RNIQDNKQVPLLKQQAQQMIDQITKLSDQLKVKDQDLIKAKNNLLEIQYSQQNENIQLKQ 2223

Query: 723  KLEKMSAE------KISELLAKIN---HEEQSKIQTQFGIDAKIQERDLYIENIESELSK 773
            KL++          K ++  A+ N    +    +  Q   D KIQ+  + I+N   E  K
Sbjct: 2224 KLQESELNLQYWKTKCADTEAEKNMWISQYNQSVLNQIAQDKKIQDSKIEIDNQHKEYLK 2283

Query: 774  YKSRICRLEESIAVMEDRRYSLERK--ADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLM 831
             +    + E     + +    LE K  ++Q+   L+E   ++   +  +D+ +  L  + 
Sbjct: 2284 VQIDEQKKEVDSLKILNSNLQLENKILSEQINQ-LKESVTSFQYKSQFKDQYLGSL--IR 2340

Query: 832  DHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAES 891
            D +++   Q++  E++ K L K N   +EE  NL+   +++ + +   +E   +T     
Sbjct: 2341 DLEQL--NQIVRQENQEK-LSKSN---IEEQLNLEQGRNEILRKHCQELELKIKTTQNNL 2394

Query: 892  ESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEF-NTQIESAIRDKKVLNEKY 950
             S +      D E  +KR   + Q   V+       +     N +I+  I+ +  +N   
Sbjct: 2395 GSNQSIESTEDTEK-VKRNKKQKQNKQVELDNNSNTVRSNSKNEEIQKYIQQQDQINN-L 2452

Query: 951  EKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINE 1010
            EK I  +   E+Q Q+ +  I+ LN  + +L   NLEL DK   K +  +     Q  N+
Sbjct: 2453 EKQILQLQIYESQDQQNQIRIKELNEKINQLQLQNLELEDKIKLKSKVDTMLSANQNQNQ 2512

Query: 1011 IN--KLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTT--KLENMEEEMQR 1066
             +  K+  LL Q +E    LN+ IN+       ++ +     +Q  T   L+   EE+ +
Sbjct: 2513 EDEKKMIDLLVQIEE----LNKIINSQNSKEQQLIEENSLLKSQLKTLQDLQIQNEELVK 2568

Query: 1067 VSKQLLDSKQHNEE----LQILVREQDDQIK-ELKETKLTFEMNIPKTEGMIISSTIEPM 1121
              K  +  KQ  E+    L  ++ + + Q K +++E ++T + N+ K   +  S ++  +
Sbjct: 2569 FQKNYIKEKQIIEDRLKDLDQVIEKNNSQYKNKIEEQRITIK-NLEKRIDLFKSQSVNNI 2627

Query: 1122 SDDAN-NVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLET 1180
             D  N   D             +VQ+ +  ++   V  +Q    N++L+    +  ++ +
Sbjct: 2628 KDKTNFEQDFYSIQNINAEYSQQVQKLKNELEVLQVKYKQLQVDNSQLKVQSEQQNKVYS 2687

Query: 1181 LNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWK 1240
             N +  G     Q Q+NQ  SK+  L  EN      VA+  +   S   +      + + 
Sbjct: 2688 QNKKEFGE---LQFQLNQANSKV--LLLENQIKQKIVADNDNEKQSDTIKGN----DYFS 2738

Query: 1241 QHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQ 1300
              L + +A+F+  + +L ++      K + L+  +Q++      KI+  +Q   L+N+ +
Sbjct: 2739 SELIKLQAEFKNQDKKLEIE------KNQNLI--LQNNIIN-LQKIINQKQ-QELKNEKE 2788

Query: 1301 DKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYK 1360
            +       L++    +I Q + L+ +I ++  +                  ++ + + Y+
Sbjct: 2789 ESNTKFNLLEQNVNGLIQQNQSLKQQISEKTQSLQVLQNNYDQATKKLKEKMQVQ-ELYE 2847

Query: 1361 QMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKT 1420
            + Q Q +  + +++A L++                 D E+++     Q+     E+  K 
Sbjct: 2848 KQQNQ-LNQLIQDSACLQQELSRSKEEFNKKVQEQIDLESQIFNYKEQIF--KLELQLKK 2904

Query: 1421 HEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKES 1480
            ++  + +   +     ++ Q    ++R +DL  + +  +    +++ ++ +       + 
Sbjct: 2905 YQSNLNVDNISSASNTLQDQ---NDQRSQDLLNQIQ-RINSQNMQLKQSLDLVIEQNNKL 2960

Query: 1481 EIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEI 1540
              E +    ++N    + +   + +++L     E+  K+ ++     N E++I  L D+I
Sbjct: 2961 ADEVLLQKNQMNSMNQQILQYQQTISQLEDEQNEKTKKSKKIDMHSNNLELQIRELEDQI 3020

Query: 1541 TNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNK 1578
             +   +V +   ++  +   +S        Q+D    K
Sbjct: 3021 RSKDLLVNSIQLELDNYRITSSQKLSSIQNQVDEKTKK 3058



 Score =  101 bits (241), Expect = 2e-19
 Identities = 249/1328 (18%), Positives = 563/1328 (42%), Gaps = 154/1328 (11%)

Query: 141  LGDVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXX 200
            +  +T LS+ +K KD  L    +K K     +L++Q   +++++ I+ K K         
Sbjct: 2183 IDQITKLSDQLKVKDQDL----IKAK---NNLLEIQ--YSQQNENIQLKQKLQESELNLQ 2233

Query: 201  XXXXXXXXXXXEDTK--QQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANK 258
                       E      Q  +   N IA + + +D K  +  D + K+     ++E  K
Sbjct: 2234 YWKTKCADTEAEKNMWISQYNQSVLNQIAQDKKIQDSKIEI--DNQHKEYLKVQIDEQKK 2291

Query: 259  LLEAARF---EISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQ--SIEPSCEEKTEIEEK 313
             +++ +     + LE+  L++++ Q                +   S+    E+  +I  +
Sbjct: 2292 EVDSLKILNSNLQLENKILSEQINQLKESVTSFQYKSQFKDQYLGSLIRDLEQLNQIVRQ 2351

Query: 314  GSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTE---SKAVSSPSKKGSPLI 370
             + E  + + + +++ L +  N  +R+  +ELE K+ T       ++++ S         
Sbjct: 2352 ENQEKLSKSNIEEQLNLEQGRNEILRKHCQELELKIKTTQNNLGSNQSIESTEDTEKVKR 2411

Query: 371  SRKSGRNTASKMKSPWSQLSSETLNQDTDKKINK-NEIAKLEMVIQSLN----------- 418
            ++K  +N   ++ +  + + S + N++  K I + ++I  LE  I  L            
Sbjct: 2412 NKKQKQNKQVELDNNSNTVRSNSKNEEIQKYIQQQDQINNLEKQILQLQIYESQDQQNQI 2471

Query: 419  --KDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVN 476
              K+L +K   +  ++             DT+++  Q ++Q+  +   +I +    E++N
Sbjct: 2472 RIKELNEKINQLQLQNLELEDKIKLKSKVDTMLSANQNQNQE--DEKKMIDLLVQIEELN 2529

Query: 477  EIAKVQEQLKQELNDE----------IKDVNV---------KDLIEKLKSAEEQITQLND 517
            +I   Q   +Q+L +E          ++D+ +         K+ I++ +  E+++  L+ 
Sbjct: 2530 KIINSQNSKEQQLIEENSLLKSQLKTLQDLQIQNEELVKFQKNYIKEKQIIEDRLKDLDQ 2589

Query: 518  EIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSN-KEIVRLTEELHHL-------SQ 569
             I+  N          ++ +K ++K ID F   S +N K+     ++ + +       SQ
Sbjct: 2590 VIEKNNSQYKNKIEEQRITIKNLEKRIDLFKSQSVNNIKDKTNFEQDFYSIQNINAEYSQ 2649

Query: 570  KVAELEEEKGNLQLHL--VDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLV 627
            +V +L+ E   LQ+    +  D+ ++      +  +  +N  E       L ++    L+
Sbjct: 2650 QVQKLKNELEVLQVKYKQLQVDNSQLKVQSEQQNKVYSQNKKEFGELQFQLNQANSKVLL 2709

Query: 628  QELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLE-EQIDALSASKKELALVIENLK 686
             E  I Q+   + +++    +   +D   SE+  +  E +  D     +K   L+++N  
Sbjct: 2710 LENQIKQKIVADNDNEKQSDTIKGNDYFSSELIKLQAEFKNQDKKLEIEKNQNLILQNNI 2769

Query: 687  LDKEQLYGTIK-DLENDKEDIMNKLQNYIQENMD----LTDKLEKMSAEKISELLAKINH 741
            ++ +++    + +L+N+KE+   K  N +++N++        L++  +EK   L    N+
Sbjct: 2770 INLQKIINQKQQELKNEKEESNTKF-NLLEQNVNGLIQQNQSLKQQISEKTQSLQVLQNN 2828

Query: 742  EEQS------KIQTQFGIDAKIQERDLYIEN---IESELSKYKSRICR-------LEESI 785
             +Q+      K+Q Q   + +  + +  I++   ++ ELS+ K    +       LE  I
Sbjct: 2829 YDQATKKLKEKMQVQELYEKQQNQLNQLIQDSACLQQELSRSKEEFNKKVQEQIDLESQI 2888

Query: 786  AVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQED------ELVNRLAVLMDHDRVVEK 839
               +++ + LE +  +  S L     + +  T+Q+       +L+N++  +   +  +++
Sbjct: 2889 FNYKEQIFKLELQLKKYQSNLNVDNISSASNTLQDQNDQRSQDLLNQIQRINSQNMQLKQ 2948

Query: 840  QL-LEIEHENK----ELQKKNQILLEENQNLQI--SLSDMQQHYNALVEKANRTDLAESE 892
             L L IE  NK     L +KNQ+     Q LQ   ++S ++   N   +K+ + D+    
Sbjct: 2949 SLDLVIEQNNKLADEVLLQKNQMNSMNQQILQYQQTISQLEDEQNEKTKKSKKIDM---H 3005

Query: 893  STKYQTQLRDLESNLKR---ITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEK 949
            S   + Q+R+LE  ++    + +  Q  +   +            Q++   +  + L + 
Sbjct: 3006 SNNLELQIRELEDQIRSKDLLVNSIQLELDNYRITSSQKLSSIQNQVDEKTKKVEKLEQI 3065

Query: 950  YEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELID--KHVQKQQTQSPDYTEQY 1007
            Y+++ +   +   +L +    I+NL + +  L   NL +++    +Q+++       +Q 
Sbjct: 3066 YQESEKNFQKHLVELSKKDQAIKNLQIQMSALESKNLHVVNDLNLIQQREATLNTQVKQL 3125

Query: 1008 INEINKLNALLKQKDEEIIALNQKINNAQV---SYMSMVSDYESKLAQ-FTTKLENMEEE 1063
            + E ++L A     D   + L+  I   Q+    +++ ++  + ++   F  +L+   E+
Sbjct: 3126 VQENSQLRAQKIISDASQMNLSALIKENQILKEQHLTKIALIKYQVKNLFNHELKQSIEK 3185

Query: 1064 MQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEP--- 1120
            ++++S Q    +Q +  +QIL ++  ++  + +  + T+     K++  I +  ++    
Sbjct: 3186 VKQISLQ--KEQQLHATIQILQQQLQEEKSKYESLQTTYTSRNKKSQEHINADELKQNQI 3243

Query: 1121 -MSDDANNVDXXXXXXXXXXXXLKVQEE----EEFIQERSV--LQEQSAKLNT-EL---- 1168
             +S+   + D             +V  +    ++FI+E SV  LQ Q    N+ EL    
Sbjct: 3244 IISNKYQSTDLILDPQQIFSTLSQVVNDNTSLKKFIEEMSVKILQMQETLHNSLELLWKE 3303

Query: 1169 QECYTKI---IQLETLNTELTGHDVVNQ-----EQINQLKSKLEQLNTENDNLLSTVAEL 1220
            Q  +       Q E  N+ +  H +  Q     + +NQLK   ++ N  + NL    +  
Sbjct: 3304 QNVFMSCNLDTQEEQTNSSIQHHQIEKQVKQIIQNLNQLKMHKDEQNVSSGNLNYQDSSS 3363

Query: 1221 RSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELR--VQLSAFESKYEQLLDSVQSS 1278
                  A++++  +        L Q     Q T+ EL   VQ   F  K  +LL +   +
Sbjct: 3364 LPISLQAINKQQEDDGNNQSCLLKQITQFTQYTQQELENVVQQIEFLEKQNKLLKNQLQN 3423

Query: 1279 TQEETNKI-----VTMEQV------TSLQNKLQDKE-EHLRNLQEKYADVINQIEILRSE 1326
            TQ+E NK+     V  EQ       T L + +  +E E  + L+E+  +++ Q+      
Sbjct: 3424 TQKENNKLLIELKVVKEQYINTKYSTILHSSIMKQEGEQSQELKEQNQNILQQLSNTNIS 3483

Query: 1327 IEDEKVAF 1334
             E++K+ +
Sbjct: 3484 -EEQKIVY 3490



 Score = 84.2 bits (199), Expect = 3e-14
 Identities = 203/1054 (19%), Positives = 452/1054 (42%), Gaps = 112/1054 (10%)

Query: 151  IKEK-DNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKN--KATTXXXXXXXXXXXXX 207
            +K K D  LS  Q + +  E  ++DL  +I E ++II ++N  +                
Sbjct: 2496 LKSKVDTMLSANQNQNQEDEKKMIDLLVQIEELNKIINSQNSKEQQLIEENSLLKSQLKT 2555

Query: 208  XXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISS-LEEANKLLEAARFE 266
                +   +++ K Q+N+I  +   +D  + L + IE  + +  + +EE    ++     
Sbjct: 2556 LQDLQIQNEELVKFQKNYIKEKQIIEDRLKDLDQVIEKNNSQYKNKIEEQRITIKNLEKR 2615

Query: 267  ISLEHSKLAQELEQXXXXXXXXXXXXXXLAK--QSIEPSCEEKTEIEEK-GSLEIANMTE 323
            I L  S+    ++                A+  Q ++    E   ++ K   L++ N ++
Sbjct: 2616 IDLFKSQSVNNIKDKTNFEQDFYSIQNINAEYSQQVQKLKNELEVLQVKYKQLQVDN-SQ 2674

Query: 324  LTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMK 383
            L  + E    +  Q ++   EL+ +L      SK +   ++    +++       +  +K
Sbjct: 2675 LKVQSEQQNKVYSQNKKEFGELQFQLNQ--ANSKVLLLENQIKQKIVADNDNEKQSDTIK 2732

Query: 384  ------SPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVI-SEKDTXXX 436
                  S   +L +E  NQD   +I KN+   L+  I +L K +  K+  + +EK+    
Sbjct: 2733 GNDYFSSELIKLQAEFKNQDKKLEIEKNQNLILQNNIINLQKIINQKQQELKNEKEESNT 2792

Query: 437  XXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLK-QELNDEIKD 495
                     + LI Q Q   QQ  E    + V  N  D     K++E+++ QEL ++ ++
Sbjct: 2793 KFNLLEQNVNGLIQQNQSLKQQISEKTQSLQVLQNNYD-QATKKLKEKMQVQELYEKQQN 2851

Query: 496  VNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKS---NHK-------LKLKQMQKT-- 543
              +  LI+     ++++++  +E +   +  I ++S   N+K       L+LK+ Q    
Sbjct: 2852 -QLNQLIQDSACLQQELSRSKEEFNKKVQEQIDLESQIFNYKEQIFKLELQLKKYQSNLN 2910

Query: 544  IDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQ--LHLVDYDSGRMIESDVYKK 601
            +DN S  S++ ++  +  +    L  ++  +  +   L+  L LV   + ++ +  + +K
Sbjct: 2911 VDNISSASNTLQD--QNDQRSQDLLNQIQRINSQNMQLKQSLDLVIEQNNKLADEVLLQK 2968

Query: 602  --MIEMENLAETRLKAISLLESQKFDLVQ-----ELHI--LQQKYDEVEDK------LAD 646
              M  M        + IS LE ++ +  +     ++H   L+ +  E+ED+      L +
Sbjct: 2969 NQMNSMNQQILQYQQTISQLEDEQNEKTKKSKKIDMHSNNLELQIRELEDQIRSKDLLVN 3028

Query: 647  ISQLQSD--QVCSEIKSVHLEEQIDALSASKKELALVIENLK-------LDKEQLYGTIK 697
              QL+ D  ++ S  K   ++ Q+D  +   ++L  + +  +       ++  +    IK
Sbjct: 3029 SIQLELDNYRITSSQKLSSIQNQVDEKTKKVEKLEQIYQESEKNFQKHLVELSKKDQAIK 3088

Query: 698  DLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKI---QTQFGID 754
            +L+     + +K   ++  +++L  + E     ++ +L+ + +     KI    +Q  + 
Sbjct: 3089 NLQIQMSALESK-NLHVVNDLNLIQQREATLNTQVKQLVQENSQLRAQKIISDASQMNLS 3147

Query: 755  AKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYS 814
            A I+E  +  E   ++++  K ++  L        + + S+E K  Q+   LQ++Q+ ++
Sbjct: 3148 ALIKENQILKEQHLTKIALIKYQVKNLFN-----HELKQSIE-KVKQIS--LQKEQQLHA 3199

Query: 815  EYTIQEDELVNRLAVLMD-HDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQ 873
               I + +L    +           +     EH N +  K+NQI++         + D Q
Sbjct: 3200 TIQILQQQLQEEKSKYESLQTTYTSRNKKSQEHINADELKQNQIIISNKYQSTDLILDPQ 3259

Query: 874  QHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFN 933
            Q ++ L +  N     +    +   ++  ++  L      H +L +  K++   +    +
Sbjct: 3260 QIFSTLSQVVNDNTSLKKFIEEMSVKILQMQETL------HNSLELLWKEQNVFMSCNLD 3313

Query: 934  TQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKN--NIENLNMNVEELNKM--NLELI 989
            TQ E    +  + + + EK ++ + Q   QL+ +K+  N+ + N+N ++ + +  +L+ I
Sbjct: 3314 TQEEQT--NSSIQHHQIEKQVKQIIQNLNQLKMHKDEQNVSSGNLNYQDSSSLPISLQAI 3371

Query: 990  DKHVQ----------KQQTQSPDYTEQYI-NEINKLNALLKQKD--EEIIALNQKINNAQ 1036
            +K  +          KQ TQ   YT+Q + N + ++  L KQ    +  +   QK NN  
Sbjct: 3372 NKQQEDDGNNQSCLLKQITQFTQYTQQELENVVQQIEFLEKQNKLLKNQLQNTQKENNKL 3431

Query: 1037 VSYMSMVSD-----------YESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILV 1085
            +  + +V +           + S + Q   + + ++E+ Q + +QL ++    E+  + +
Sbjct: 3432 LIELKVVKEQYINTKYSTILHSSIMKQEGEQSQELKEQNQNILQQLSNTNISEEQKIVYL 3491

Query: 1086 REQDDQIKELKETKLTFEMNIPKTEGMIISSTIE 1119
              Q+ Q+ E+ +   TF++N  K    + SS I+
Sbjct: 3492 MMQNKQLIEMIK---TFQINEAKRSEQLNSSNIQ 3522



 Score = 56.4 bits (130), Expect = 6e-06
 Identities = 162/822 (19%), Positives = 350/822 (42%), Gaps = 90/822 (10%)

Query: 212  EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEE-ANKLLEAARFEISLE 270
            E  K Q   +Q N I ++     ++Q L  + E  + + + LE+  N L++        +
Sbjct: 2756 EIEKNQNLILQNNIINLQKIINQKQQELKNEKEESNTKFNLLEQNVNGLIQ--------Q 2807

Query: 271  HSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIEL 330
            +  L Q++ +                K+      +EK +++E    +   + +L +    
Sbjct: 2808 NQSLKQQISEKTQSLQVLQNNYDQATKK-----LKEKMQVQELYEKQQNQLNQLIQDSAC 2862

Query: 331  L-EHLNCQIRQTNK------ELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMK 383
            L + L+    + NK      +LE+++     +   +    KK    ++  +  + ++ ++
Sbjct: 2863 LQQELSRSKEEFNKKVQEQIDLESQIFNYKEQIFKLELQLKKYQSNLNVDNISSASNTLQ 2922

Query: 384  SPWSQLSSETLNQDTDKKINKNEI---AKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXX 440
                Q S + LNQ   ++IN   +     L++VI+  NK L D+  V+ +K+        
Sbjct: 2923 DQNDQRSQDLLNQ--IQRINSQNMQLKQSLDLVIEQNNK-LADE--VLLQKNQMNSMNQQ 2977

Query: 441  XXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQE------LNDEIK 494
                + T I+QL+ E  +  +    I + +N  ++ +I ++++Q++ +      +  E+ 
Sbjct: 2978 ILQYQQT-ISQLEDEQNEKTKKSKKIDMHSNNLEL-QIRELEDQIRSKDLLVNSIQLELD 3035

Query: 495  DVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSN---HKLKLKQMQKTIDN----F 547
            +  +    +KL S + Q+ +   +++   +   + + N   H ++L +  + I N     
Sbjct: 3036 NYRITS-SQKLSSIQNQVDEKTKKVEKLEQIYQESEKNFQKHLVELSKKDQAIKNLQIQM 3094

Query: 548  SKVSDSNKEIVR----LTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMI 603
            S +   N  +V     + +    L+ +V +L +E   L+   +  D+ +M  S + K   
Sbjct: 3095 SALESKNLHVVNDLNLIQQREATLNTQVKQLVQENSQLRAQKIISDASQMNLSALIK--- 3151

Query: 604  EMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVED-KLADISQLQS-----DQVCS 657
            E + L E  L  I+L++ Q  +L    H L+Q  ++V+   L    QL +      Q   
Sbjct: 3152 ENQILKEQHLTKIALIKYQVKNLFN--HELKQSIEKVKQISLQKEQQLHATIQILQQQLQ 3209

Query: 658  EIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIK----DLENDKEDIMNKLQNY 713
            E KS +   Q    S +KK    +  + +L + Q+  + K    DL  D + I + L   
Sbjct: 3210 EEKSKYESLQTTYTSRNKKSQEHINAD-ELKQNQIIISNKYQSTDLILDPQQIFSTLSQV 3268

Query: 714  IQENMDLTDKLEKMSAEKISELLAKINHE-----EQSKIQTQFGIDAKIQERDLYIENIE 768
            + +N  L   +E+MS  KI ++   +++      ++  +     +D + ++ +  I++ +
Sbjct: 3269 VNDNTSLKKFIEEMSV-KILQMQETLHNSLELLWKEQNVFMSCNLDTQEEQTNSSIQHHQ 3327

Query: 769  SELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLA 828
             E  + K  I  L +     +++  S      Q  S L    +A ++   QED+  N+  
Sbjct: 3328 IE-KQVKQIIQNLNQLKMHKDEQNVSSGNLNYQDSSSLPISLQAINKQ--QEDDGNNQSC 3384

Query: 829  VLMDHDRVVE--KQLLE--------IEHENKELQKKNQILLEENQNLQISLSDMQQHYNA 878
            +L    +  +  +Q LE        +E +NK L+ + Q   +EN  L I L  +++ Y  
Sbjct: 3385 LLKQITQFTQYTQQELENVVQQIEFLEKQNKLLKNQLQNTQKENNKLLIELKVVKEQY-- 3442

Query: 879  LVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIES 938
             +     T L  S   +   Q ++L+   + I  +     + ++++I  L ++ N Q+  
Sbjct: 3443 -INTKYSTILHSSIMKQEGEQSQELKEQNQNILQQLSNTNISEEQKIVYLMMQ-NKQLIE 3500

Query: 939  AIRDKKVLNEKYEKNIEYVT-QLEAQLQEYKNNIENLNMNVE 979
             I+  ++   K  + +     QL   L++   N ++ N N E
Sbjct: 3501 MIKTFQINEAKRSEQLNSSNIQLYMALKDIA-NFKSKNFNFE 3541


>UniRef50_UPI00015A6057 Cluster: UPI00015A6057 related cluster; n=1;
            Danio rerio|Rep: UPI00015A6057 UniRef100 entry - Danio
            rerio
          Length = 1894

 Score =  142 bits (345), Expect = 5e-32
 Identities = 255/1308 (19%), Positives = 560/1308 (42%), Gaps = 101/1308 (7%)

Query: 313  KGSLEIAN-MTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLIS 371
            +G +E A  +TE  +K    EH+    RQ  K+ E+++       K + +   + + L  
Sbjct: 534  RGQVEEAEKLTEELRKEN--EHMR---RQREKQEEDRIQQDRERHKRMEAEMLESAQLCE 588

Query: 372  RKSGRNTASKMKSPWSQLSSETLNQ---DTDKKINKNEIAKLE--MVIQSLNKDLVDKEY 426
            R+S   T  ++      L  ETL++   + + +  K+ + K    ++ QS  ++ + +E 
Sbjct: 589  RES--RTRLELHRLQVALERETLDRARAEQEAEQAKDALIKARESLLAQSSGQNQLKREL 646

Query: 427  VISEKDTXXXXXXXXXXGKDTL---IAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQE 483
              +               KD     +  LQL  Q       L  V     ++ + A++Q 
Sbjct: 647  AGAGDALEKMAALNEALAKDKRELGVRSLQLTEQCSTVMKELQSVKV---ELLKAAELQR 703

Query: 484  QLKQELNDEIKDVN-VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQK 542
            + ++E +D +++   ++D +  L+  +E++ Q+ +E+  + + +  ++++ + +  Q ++
Sbjct: 704  RAERERDDLMRESQRLEDTVCTLEREKEELAQVKEELRYSQREIQCLQTDLERETAQKER 763

Query: 543  TIDNFSKVSDSNKEIVRLTEELHHLSQKV-----AELEEEKGNLQLHLVDYDSGRMIESD 597
             +    + S+++K     ++      QK      AEL ++ G +++ L +   G + E +
Sbjct: 764  ELQESIEESENSKIQAEESKTDRERWQKERESLSAELGQKDGEVEI-LRNRIDGLLKEKE 822

Query: 598  VYKKMIEMENLAETRLKAISLLESQKFDL-----VQELHILQQKYDEVEDKLADISQLQS 652
                 +E  N    +L+  S  E +  +L       E+   +++ ++V+ +  +++Q   
Sbjct: 823  ELLDHLEKRNTELEKLQTKSAAEQKAAELRLRGACDEVERWKERENKVQREKEELNQKFL 882

Query: 653  DQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQN 712
            ++V  E +++ + ++       K +++ +++  + +KE L   ++ LE     +  K  +
Sbjct: 883  ERVERESQNLEITQR------EKAKMSDLMKKKEDEKETLESRVETLEKLNTQLKEKKLD 936

Query: 713  YIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERD---LYIENIES 769
             I+EN     K ++   EK      ++  +++  I+ +  ID  I E++   L +E  E 
Sbjct: 937  KIRENESRQKKRDEQEREKEVRWRRQLEQKDEGLIELKSRIDELIGEKEHISLLVEEREK 996

Query: 770  ELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAV 829
            ++ + +S +   +E    ++ R    E K +QL   L E+     +   +  E VNR   
Sbjct: 997  DIEQLQSTLSTEKEREEEVQKR----EEKNEQL-ELLNEQISQIKKLKAEHAE-VNRCKA 1050

Query: 830  LMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLA 889
             +      +  L E + E ++ QK  + +  E + L++ + ++ Q     +E+  R  + 
Sbjct: 1051 KIAEMEQDQVNLKERDEEQRKRQKMEKDV--EVRQLKLKIEELNQE----IEQDRRIRME 1104

Query: 890  ESESTKYQTQL-RDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNE 948
            + E  + QT L RD E   + +    Q    QK KE  D  +    + ++ +++K  L+E
Sbjct: 1105 QQEDLEQQTALLRDAEEEARTLKKTLQ----QKDKEERD-RLHHEEKEKTLLKEK--LHE 1157

Query: 949  KYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLEL-IDKHVQKQQTQSPDYTEQY 1007
              ++NI+ ++ L+      +     L    E L + N EL + K  + Q+ +S +   + 
Sbjct: 1158 AEQRNIKVLSSLQEIETTLEKERYQLRGKEERLMECNEELFLIKRERDQEKESIEELNKL 1217

Query: 1008 INEINK----LNALLKQKDEEIIALNQKINNAQVSYM---SMVSDYESKLAQFTTKLENM 1060
            I E  K    L   L ++ EE   L++ + N +V      S   + E +  Q    L  +
Sbjct: 1218 IGEQGKEVKTLRGKLDERLEEEGRLSKLLQNQRVEVQVLESRAENIEEEKQQLKRSLSQI 1277

Query: 1061 EEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEP 1120
            EEE + +  QL D K   E L++ + +Q  ++ +L   K+  E    K   ++ +S +E 
Sbjct: 1278 EEEKRHLETQLTDEKVDKERLRVRLEDQATEVTKLN--KILEEER--KLSQLLQNSRVEA 1333

Query: 1121 MSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLET 1180
               ++   +             ++++EE  + +      Q++++  ++ E   + I++E 
Sbjct: 1334 QMFESRAQNTEEEKQLLKRSLSQIEKEERKLSQLL----QNSRVEAQMLESRAENIEVEK 1389

Query: 1181 LNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWK 1240
               + +   +  +E+   L ++L     + + L + V +  + ++   ++    I E  +
Sbjct: 1390 QQLKRSLTQI--EEEKRHLGTQLTDEKMDKERLRAWVEDQATEVTKLKEKLSEMIEE--E 1445

Query: 1241 QHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQ 1300
            + L+Q   + +   H L  +    E + +QL    +S TQ E  K       T L ++  
Sbjct: 1446 RKLSQLLQNSRVEAHILESRTENIEEEKQQL---TRSLTQIEKEK---RHLETQLTDEKM 1499

Query: 1301 DKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYK 1360
            DKE     L+++  +V    E L   IE+E+                   + R EN   +
Sbjct: 1500 DKERLRARLKDQATEVTKLKEKLNEMIEEER---KLSQLLQNSRVEAQMLESRAENTIEE 1556

Query: 1361 QMQEQSILN-INEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQL------ELKD 1413
            + Q + +L+ + EE   L+               R+ D   +V +L  +L      E K 
Sbjct: 1557 KQQLKRVLSQVEEEKRLLETQLTDEKIDRERLKARLEDQATEVTKLKEKLNKMVEDERKL 1616

Query: 1414 SEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHY 1473
            S + Q +   T  L  R +  E  +QQL     +IE+     E++L   ++         
Sbjct: 1617 SHLLQNSQVETQMLESRTENLEEEKQQLKRSLTQIEEEKRCLETQLTDEKIDRERLRARL 1676

Query: 1474 ETMQKESEIERVK-LIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIE 1532
            E  Q  S +   K   E L+V++    SL +Q+  L+++ E+   K  E +   +     
Sbjct: 1677 EDFQISSLLSDAKERKESLSVQVD---SLQEQLVSLSRSKEQTKLKIQEQKEQNKEMREG 1733

Query: 1533 IVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKEL 1580
            +V    E+  L+ ++  S  + ++  S     ++ + E L+ T+  ++
Sbjct: 1734 LVAGLQEMATLKELLEESHREGERLRSMMQMLEKQKQE-LETTLQLQV 1780



 Score =  122 bits (294), Expect = 8e-26
 Identities = 211/1119 (18%), Positives = 479/1119 (42%), Gaps = 97/1119 (8%)

Query: 147  LSNTIKEKDNALSVLQVKMKIM---ETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXX 203
            LS  + +KD  + +L+ ++  +   +  +LD  EK N + + ++ K+ A           
Sbjct: 796  LSAELGQKDGEVEILRNRIDGLLKEKEELLDHLEKRNTELEKLQTKSAAEQKAAELRLRG 855

Query: 204  XXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAA 263
                    ++ + ++ + +E       E  + + + L+  + +  ++S L +  K  E  
Sbjct: 856  ACDEVERWKERENKVQREKEELNQKFLERVERESQNLEITQREKAKMSDLMK-KKEDEKE 914

Query: 264  RFEISLEH-SKLAQEL-EQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANM 321
              E  +E   KL  +L E+                +Q  E     + ++E+K    I   
Sbjct: 915  TLESRVETLEKLNTQLKEKKLDKIRENESRQKKRDEQEREKEVRWRRQLEQKDEGLIELK 974

Query: 322  TELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASK 381
            + + + I   EH++  + +  K++E   +T+ TE +      K+               +
Sbjct: 975  SRIDELIGEKEHISLLVEEREKDIEQLQSTLSTEKEREEEVQKR---------------E 1019

Query: 382  MKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXX 441
             K+   +L +E ++Q    K    E+ + +  I  + +D V+    + E+D         
Sbjct: 1020 EKNEQLELLNEQISQIKKLKAEHAEVNRCKAKIAEMEQDQVN----LKERDEEQRKRQKM 1075

Query: 442  XXGKDTLIAQLQL---EHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNV 498
               KD  + QL+L   E  Q +E    I +    ED+ +   +    ++E     K +  
Sbjct: 1076 E--KDVEVRQLKLKIEELNQEIEQDRRIRM-EQQEDLEQQTALLRDAEEEARTLKKTLQQ 1132

Query: 499  KDLIEK--LKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFS-KVSDSNK 555
            KD  E+  L   E++ T L +++  A +  IKV S+    L++++ T++    ++    +
Sbjct: 1133 KDKEERDRLHHEEKEKTLLKEKLHEAEQRNIKVLSS----LQEIETTLEKERYQLRGKEE 1188

Query: 556  EIVRLTEELHHLSQKVAELEEEKGNLQ-LHLVDYDSGRMIES---DVYKKMIE---MENL 608
             ++   EEL  + +   E ++EK +++ L+ +  + G+ +++    + +++ E   +  L
Sbjct: 1189 RLMECNEELFLIKR---ERDQEKESIEELNKLIGEQGKEVKTLRGKLDERLEEEGRLSKL 1245

Query: 609  AETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADI-SQLQSDQVCSEIKSVHLEEQ 667
             + +   + +LES+  ++ +E   L++   ++E++   + +QL  ++V  E   V LE+Q
Sbjct: 1246 LQNQRVEVQVLESRAENIEEEKQQLKRSLSQIEEEKRHLETQLTDEKVDKERLRVRLEDQ 1305

Query: 668  ------IDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLT 721
                  ++ +   +++L+ +++N +++ +      ++ E +K+ +   L    +E   L+
Sbjct: 1306 ATEVTKLNKILEEERKLSQLLQNSRVEAQMFESRAQNTEEEKQLLKRSLSQIEKEERKLS 1365

Query: 722  DKLE--KMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRIC 779
              L+  ++ A+ +      I  E+Q   ++   I+   ++R L  +  + ++ K + R  
Sbjct: 1366 QLLQNSRVEAQMLESRAENIEVEKQQLKRSLTQIEE--EKRHLGTQLTDEKMDKERLR-- 1421

Query: 780  RLEESIAVMEDRRYSLERKADQLGSYLQEKQKA---YSEYTIQEDELVNRLAVLMDHDRV 836
                  A +ED+   + +  ++L   ++E++K         ++   L +R   + +  + 
Sbjct: 1422 ------AWVEDQATEVTKLKEKLSEMIEEERKLSQLLQNSRVEAHILESRTENIEEEKQQ 1475

Query: 837  VEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKY 896
            + + L +IE E + L+ +      + + L+  L D       L EK N   + E      
Sbjct: 1476 LTRSLTQIEKEKRHLETQLTDEKMDKERLRARLKDQATEVTKLKEKLNEM-IEEERKLSQ 1534

Query: 897  QTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEY 956
              Q   +E+ +     E+     Q+ K +     E    +E+ + D+K+  E+ +     
Sbjct: 1535 LLQNSRVEAQMLESRAENTIEEKQQLKRVLSQVEEEKRLLETQLTDEKIDRERLK----- 1589

Query: 957  VTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNA 1016
              +LE Q  E     E LN  VE+  K++  L +  V+ Q  +S   TE    E  +L  
Sbjct: 1590 -ARLEDQATEVTKLKEKLNKMVEDERKLSHLLQNSQVETQMLESR--TENLEEEKQQLKR 1646

Query: 1017 LLKQKDEEIIALNQKINNAQVS---YMSMVSDYE--SKLAQFTTKLENMEEEMQRVSKQL 1071
             L Q +EE   L  ++ + ++      + + D++  S L+    + E++  ++  + +QL
Sbjct: 1647 SLTQIEEEKRCLETQLTDEKIDRERLRARLEDFQISSLLSDAKERKESLSVQVDSLQEQL 1706

Query: 1072 LDSKQHNEELQILVREQDDQIKELKETKLTF--EMNIPKT-------EGMIISSTIEPMS 1122
            +   +  E+ ++ ++EQ +Q KE++E  +    EM   K        EG  + S ++ + 
Sbjct: 1707 VSLSRSKEQTKLKIQEQKEQNKEMREGLVAGLQEMATLKELLEESHREGERLRSMMQMLE 1766

Query: 1123 DDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLN 1182
                 ++            LK ++ EE +QE+  LQ++  KL  EL    +     E   
Sbjct: 1767 KQKQELETTLQLQVEQ---LK-KKNEEGMQEKEQLQQRQEKLEGELMAMKSVKEHREAEL 1822

Query: 1183 TELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELR 1221
            T       + ++Q  +L S   +   + + L +   +LR
Sbjct: 1823 TRAKARLDILEDQRTELSSLAAERTKDAEELSNRFRDLR 1861



 Score =  110 bits (264), Expect = 4e-22
 Identities = 192/977 (19%), Positives = 428/977 (43%), Gaps = 92/977 (9%)

Query: 141  LGDVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXX 200
            +G+  H+S  ++E++  +  LQ  +   +    ++Q++  EK++ +E  N+  +      
Sbjct: 981  IGEKEHISLLVEEREKDIEQLQSTLSTEKEREEEVQKR-EEKNEQLELLNEQISQIKKLK 1039

Query: 201  XXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLL 260
                       +    +M + Q N    + E + ++Q++ KD+E + +++  +EE N+ +
Sbjct: 1040 AEHAEVNRCKAKIA--EMEQDQVNLKERDEEQR-KRQKMEKDVEVRQLKLK-IEELNQEI 1095

Query: 261  EAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIAN 320
            E  R  I +E     ++LEQ              L K   +   EE+  +      E   
Sbjct: 1096 EQDR-RIRMEQQ---EDLEQQTALLRDAEEEARTLKKTLQQKDKEERDRLHH----EEKE 1147

Query: 321  MTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKK-GSPLISRKSGRNTA 379
             T L +K+   E  N ++  + +E+E  L     + +       +    L   K  R+  
Sbjct: 1148 KTLLKEKLHEAEQRNIKVLSSLQEIETTLEKERYQLRGKEERLMECNEELFLIKRERDQE 1207

Query: 380  SKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXX 439
             +     ++L  E   Q  + K  + ++ +       L+K L ++   +   ++      
Sbjct: 1208 KESIEELNKLIGE---QGKEVKTLRGKLDERLEEEGRLSKLLQNQRVEVQVLESRAENIE 1264

Query: 440  XXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVK 499
                     ++Q++ E ++H+E        T   D  ++ K  E+L+  L D+  +V   
Sbjct: 1265 EEKQQLKRSLSQIE-EEKRHLE--------TQLTD-EKVDK--ERLRVRLEDQATEVTK- 1311

Query: 500  DLIEKLKSAEEQITQL--NDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEI 557
              + K+   E +++QL  N  ++A    M + ++ +  + KQ+ K   + S++    +++
Sbjct: 1312 --LNKILEEERKLSQLLQNSRVEA---QMFESRAQNTEEEKQLLKR--SLSQIEKEERKL 1364

Query: 558  VRLTE----ELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRL 613
             +L +    E   L  +   +E EK  L+  L   +     E       +  E + + RL
Sbjct: 1365 SQLLQNSRVEAQMLESRAENIEVEKQQLKRSLTQIEE----EKRHLGTQLTDEKMDKERL 1420

Query: 614  KAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSA 673
            +A   +E Q  ++ +    L++K  E+ ++   +SQL  +   S +++  LE + + +  
Sbjct: 1421 RA--WVEDQATEVTK----LKEKLSEMIEEERKLSQLLQN---SRVEAHILESRTENIEE 1471

Query: 674  SKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAE--K 731
             K++L   +  ++ +K  L   + D + DKE +  +L++   E   L +KL +M  E  K
Sbjct: 1472 EKQQLTRSLTQIEKEKRHLETQLTDEKMDKERLRARLKDQATEVTKLKEKLNEMIEEERK 1531

Query: 732  ISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDR 791
            +S+LL      + S+++ Q      ++ R    EN   E  + K  + ++EE   ++E +
Sbjct: 1532 LSQLL------QNSRVEAQM-----LESR---AENTIEEKQQLKRVLSQVEEEKRLLETQ 1577

Query: 792  RYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKEL 851
                +   ++L + L+++    +E T    +L  +L  +++ +R +   L   + E + L
Sbjct: 1578 LTDEKIDRERLKARLEDQA---TEVT----KLKEKLNKMVEDERKLSHLLQNSQVETQML 1630

Query: 852  QKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRIT 911
            + + + L EE Q L+ SL+ +++    L E     +  + E  + + +   + S L    
Sbjct: 1631 ESRTENLEEEKQQLKRSLTQIEEEKRCL-ETQLTDEKIDRERLRARLEDFQISSLLSDAK 1689

Query: 912  HEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEY---K 968
               ++L VQ    ++ L+ +  +   S  + K  + E+ E+N E    L A LQE    K
Sbjct: 1690 ERKESLSVQ----VDSLQEQLVSLSRSKEQTKLKIQEQKEQNKEMREGLVAGLQEMATLK 1745

Query: 969  NNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIAL 1028
              +E  +   E L  M +++++K  QKQ+ ++    +  + ++ K N    Q+ E++   
Sbjct: 1746 ELLEESHREGERLRSM-MQMLEK--QKQELETT--LQLQVEQLKKKNEEGMQEKEQLQQR 1800

Query: 1029 NQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQ 1088
             +K+    ++  S+    E++L +   +L+ +E++   +S    +  +  EEL    R+ 
Sbjct: 1801 QEKLEGELMAMKSVKEHREAELTRAKARLDILEDQRTELSSLAAERTKDAEELSNRFRDL 1860

Query: 1089 DDQIKELKETKLTFEMN 1105
              +   L+E ++  + N
Sbjct: 1861 RLEADRLREDRIREKNN 1877



 Score = 55.6 bits (128), Expect = 1e-05
 Identities = 172/976 (17%), Positives = 378/976 (38%), Gaps = 52/976 (5%)

Query: 600  KKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEI 659
            KK+ E       +   I  L+ +  D       L+Q+    E +L    ++  D+    +
Sbjct: 66   KKLREGREREARQALLIHKLQHKVLDYRARCQALEQQAVGEERELRIRERILRDERSDTL 125

Query: 660  KS--VHLEEQIDALSASKKEL-ALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQE 716
            +S  + LEE+  + S    E+ AL+   L    E       DL     D    ++  +Q+
Sbjct: 126  ESTLIRLEEEQQSRSLGLSEVSALLRSQLSQSTEANEALRDDLRKLTADWSKAVEEVVQK 185

Query: 717  NMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENI-ESELSKYK 775
             +D          +K  E+L     +E S++ T +G    ++ +   ++   + +L + K
Sbjct: 186  EIDW---------QKEKEVLTGYIGKEHSRLMTLWGRVVTLRRQCHSLKTATDKDLWELK 236

Query: 776  SRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDR 835
            +   RL  S+  +     S  +      S L +   A    T Q    ++ L      +R
Sbjct: 237  ADFSRLSSSLLSVWASPLSAPKLTHN--SSLSQSTSAQPLSTTQGPLSLDDLNHEQTDER 294

Query: 836  VVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLA--ESES 893
               +   +IE E  EL+ +   + E N  ++   S+ ++    + E+ +R ++   + + 
Sbjct: 295  KSSELKADIESETLELRNR---ITELNMTVKALESEREKQEEEM-ERRHRHEMEREQEQE 350

Query: 894  TKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKN 953
             K++ Q+ +LE N + +    +TL+ Q+  + E+L  +F   I+      K+ ++K    
Sbjct: 351  RKWERQM-ELERNFESVCQAVKTLVSQRIDDSENL-FQFKGAIKCIDTLFKLFSDK-SPE 407

Query: 954  IEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINK 1013
               +  LEA           L++  +   +  L+  ++ VQ  Q     +       +N+
Sbjct: 408  TSPLRSLEADDASSDGLCSVLSVIAQA--ETALQWREQEVQVDQYDIKIHRFLTSLFMNE 465

Query: 1014 LNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLD 1073
                L++   E  +L Q+I   +  ++ +         Q     E +      +    + 
Sbjct: 466  AQMSLRRLGTEKESLEQRITQLESEWVELQEQTNQGALQIKHTQELLNRVKLNIRHSFMM 525

Query: 1074 SKQHNEELQILVREQDDQIKEL-KETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXX 1132
            SK+  + L+  V E +   +EL KE +        + E  I          +A  ++   
Sbjct: 526  SKKMLKNLRGQVEEAEKLTEELRKENEHMRRQREKQEEDRIQQDRERHKRMEAEMLESAQ 585

Query: 1133 XXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQL-ETLNTELTGHDVV 1191
                     L++   +  + ER  L    A+   E ++    +I+  E+L  + +G + +
Sbjct: 586  LCERESRTRLELHRLQVAL-ERETLDR--ARAEQEAEQAKDALIKARESLLAQSSGQNQL 642

Query: 1192 NQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHL-AQREADF 1250
             +E +      LE++   N+ L     EL        +Q    + EL    +   + A+ 
Sbjct: 643  KRE-LAGAGDALEKMAALNEALAKDKRELGVRSLQLTEQCSTVMKELQSVKVELLKAAEL 701

Query: 1251 QKTEHELRVQLSAFESKYEQLLDSVQSSTQE----ETNKIVTMEQVTSLQNKLQ-DKEEH 1305
            Q+     R  L     + E  + +++   +E    +     +  ++  LQ  L+ +  + 
Sbjct: 702  QRRAERERDDLMRESQRLEDTVCTLEREKEELAQVKEELRYSQREIQCLQTDLERETAQK 761

Query: 1306 LRNLQEKYADVIN-QIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXD-LRTENQSYKQMQ 1363
             R LQE   +  N +I+   S+ + E+                   + LR       + +
Sbjct: 762  ERELQESIEESENSKIQAEESKTDRERWQKERESLSAELGQKDGEVEILRNRIDGLLKEK 821

Query: 1364 EQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEY 1423
            E+ + ++ + N +L+K              R+  A  +V     + + +++++ ++  E 
Sbjct: 822  EELLDHLEKRNTELEKLQTKSAAEQKAAELRLRGACDEV----ERWKERENKVQREKEEL 877

Query: 1424 TITLTQRNDEFENVRQQLVEYEK-RIEDLTYEKESELAILRLKMHENANHYETMQKESEI 1482
                 +R  E E+   ++ + EK ++ DL  +KE E   L  ++ E      T  KE ++
Sbjct: 878  NQKFLER-VERESQNLEITQREKAKMSDLMKKKEDEKETLESRV-ETLEKLNTQLKEKKL 935

Query: 1483 ERVKLIEELNVKITE-----SVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLN 1537
            ++++  E    K  E      V   +Q+ + ++ L E  ++ +E+    E+  + +    
Sbjct: 936  DKIRENESRQKKRDEQEREKEVRWRRQLEQKDEGLIELKSRIDELIGEKEHISLLVEERE 995

Query: 1538 DEITNLQNMVRASSSK 1553
             +I  LQ+ +     +
Sbjct: 996  KDIEQLQSTLSTEKER 1011



 Score = 37.9 bits (84), Expect = 2.3
 Identities = 76/412 (18%), Positives = 167/412 (40%), Gaps = 27/412 (6%)

Query: 146  HLSNTIKEKDNALSVLQVKMKIMETTILDLQEKIN---EKDQIIEAKNKATTXXXXXXXX 202
            HL   + ++      L+ ++K   T +  L+EK+N   E+++ +    + +         
Sbjct: 1489 HLETQLTDEKMDKERLRARLKDQATEVTKLKEKLNEMIEEERKLSQLLQNSRVEAQMLES 1548

Query: 203  XXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEK---QRLLKDIESKDVRISSL-EEANK 258
                     +  K+ +++++E    +E +  DEK   +RL   +E +   ++ L E+ NK
Sbjct: 1549 RAENTIEEKQQLKRVLSQVEEEKRLLETQLTDEKIDRERLKARLEDQATEVTKLKEKLNK 1608

Query: 259  LLEAARFEISLEHSKLAQELE-QXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLE 317
            ++E  R    L H     ++E Q                K+S+    EEK  +E + + E
Sbjct: 1609 MVEDER---KLSHLLQNSQVETQMLESRTENLEEEKQQLKRSLTQIEEEKRCLETQLTDE 1665

Query: 318  IANMTELTKKIE--LLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSG 375
              +   L  ++E   +  L    ++  + L  ++ ++  +  ++S   ++    I  +  
Sbjct: 1666 KIDRERLRARLEDFQISSLLSDAKERKESLSVQVDSLQEQLVSLSRSKEQTKLKIQEQKE 1725

Query: 376  RNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVIS-EKDTX 434
            +N   +           TL +  ++   + E  +L  ++Q L K   + E  +  + +  
Sbjct: 1726 QNKEMREGLVAGLQEMATLKELLEESHREGE--RLRSMMQMLEKQKQELETTLQLQVEQL 1783

Query: 435  XXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIK 494
                      K+    QLQ + Q+ +EG  +           E+ + + +L   L D+  
Sbjct: 1784 KKKNEEGMQEKE----QLQ-QRQEKLEGELMAMKSVKEHREAELTRAKARL-DILEDQRT 1837

Query: 495  DVNVKDLIEKLKSAEEQITQLND---EIDAANKNMIKVKSN-HKLKLKQMQK 542
            +++     E+ K AEE   +  D   E D   ++ I+ K+N  +LK +  +K
Sbjct: 1838 ELS-SLAAERTKDAEELSNRFRDLRLEADRLREDRIREKNNWEELKRENKEK 1888


>UniRef50_A2DZ81 Cluster: Viral A-type inclusion protein, putative;
            n=1; Trichomonas vaginalis G3|Rep: Viral A-type inclusion
            protein, putative - Trichomonas vaginalis G3
          Length = 1547

 Score =  142 bits (345), Expect = 5e-32
 Identities = 258/1327 (19%), Positives = 558/1327 (42%), Gaps = 105/1327 (7%)

Query: 57   AQKCLENAALVSK---RIKEHRKATAELLGRP-FVPGISESLANTLKQKEILMEKIKQYK 112
            A++  EN+  V +    IK+ ++   E   R   +  ++E   + L   E       Q K
Sbjct: 140  AEESKENSKSVKQLEDEIKQLKQELDEQTNRADSLEEMNEKFRSLLPDSEDFESAYSQLK 199

Query: 113  ELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNALSVLQVKMKIMETTI 172
             L + S++TI                  +G +   +N IK+ +  +  L++ +      +
Sbjct: 200  SLCENSNSTIDDNDSEEKSHKKRHHKDLIGKLNEKNNEIKQLEKEIKSLKLTLSERSNEL 259

Query: 173  LDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEW 232
             +++  + EK++ IE  NK ++                 ED K++  ++++  +  E E 
Sbjct: 260  NNIRRTLAEKEEEIENLNKNSS------------NSSNEEDLKKKDEEIEK--LKEEIEK 305

Query: 233  KDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH--SKLAQELEQXXXXXXXXXX 290
             + K +  ++ E KD    S E      E +  +   +    KL ++  +          
Sbjct: 306  LNSKPQKEEENEEKDKENDSEEGEENTSEKSHHKKHHKDLIGKLNKKNNEIKQLEKEIKG 365

Query: 291  XXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQ-TNKEL-ENK 348
                L+++S E +   +T  E++ +   +N   L KK+E +E+L  +I +  NK   E +
Sbjct: 366  LKLTLSERSNELNNIRRTLAEKENN---SNDETLQKKVEEIENLKKEIEEFKNKSSNEEE 422

Query: 349  LATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIA 408
            L ++   ++ +    +K S    ++ G     K ++   +    T  +   KK +K+ I 
Sbjct: 423  LNSLRESNQKLKEEIEKLSNKPQKEEGNEEKDK-ENDSEEGEENTSEKSHHKKHHKDLIG 481

Query: 409  KLEM---VIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSL 465
            KL      I+ L K++   +  +SE+             K+      ++E+ ++ EG + 
Sbjct: 482  KLNKKNNEIKQLEKEIKSLKLTLSERSNELNNIRRTLAEKEQ-----EMENLKNGEGNT- 535

Query: 466  IHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDL-IEKLKS--AEEQITQLNDEIDAA 522
                 N E++N++ +   + K+EL    K +  KD  +E+++S      IT+ + E+++ 
Sbjct: 536  ----QNNEELNQLKEDNNKQKEELESLKKQLQDKDAELEQIRSNTNTSTITEESKEMNSD 591

Query: 523  NKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQ 582
            N +    KS  K   K+  K  D   K++  N EI +L +E+  L   ++E   E  N++
Sbjct: 592  NDDEESEKSQSKSGHKKHHK--DLIGKLNQKNNEIKQLEKEIKSLKLTLSERSNELNNIR 649

Query: 583  LHLVDYD----------SGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHI 632
              L + +          S    E D+ KK  E+++L E+  K    L ++  + +++L  
Sbjct: 650  RTLTEKEQEIDNLKKSGSNSSNEEDLKKKDEEIKSLRESNDKLQKELLTRD-EEIEKLSN 708

Query: 633  LQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASK------KELALVIENLK 686
              QK +E E+K  +    + ++  SE KS H +   D +          K+L   I+ LK
Sbjct: 709  KPQKEEENEEKDKENDSEEGEENTSE-KSHHKKHHKDLIGKLNKKNNEIKQLEKEIKGLK 767

Query: 687  LDKEQLYGTIKDLEN---DKEDIMNKLQNYIQ-ENMDLTDKLEKMSAEKISELLAKINHE 742
            L   +    + ++     +KE  M  L   +Q +N D   +L++ + +  SEL +K    
Sbjct: 768  LTLSERSNELNNIRRTLAEKEQEMENLNGSVQNKNDDEIKELQQENEKLKSELASKDAEL 827

Query: 743  EQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQL 802
            EQ +  T      + + +++  +N + E S+        ++    +  +      +  QL
Sbjct: 828  EQIRSNTNTSTITE-ESKEMNSDNDDDEESEKSQSKSGHKKHHKDLIGKLNQKNNEIKQL 886

Query: 803  GSYLQEKQKAYSEYTIQEDELVNRLAVLMD--HDRVVEKQLLEIEHENKELQ--KKNQIL 858
               ++  +   SE + + + +   LA   +  +D  ++K+  EIE+  KE+   KK+   
Sbjct: 887  EKEIKSLKLTLSERSNELNNIRRTLAEKENNSNDETLQKKEEEIENLKKEIDNLKKSSSN 946

Query: 859  LEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITH---EHQ 915
             EE ++L+  +  +++   +       T     E      +    E N    +H    H+
Sbjct: 947  EEETKSLRDEIEKLKKELESKESMNTNTSTINEEIDGEAKENDSEEENTSEKSHHKKHHK 1006

Query: 916  TLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLN 975
             LI +  ++  +++     Q+E  I+  K+   +    +  + +  A+ +E  +N E L 
Sbjct: 1007 DLIGKLNQKNNEIK-----QLEKEIKSLKLTLSERSNELNNIRRTLAE-KENNSNDETLQ 1060

Query: 976  MNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQK-INN 1034
              VEE+  +  E+       ++ ++    E+ +N + + N  LK++ E++ +  QK   N
Sbjct: 1061 KKVEEIENLKKEI-------EEFKNKSSNEEELNSLRESNQKLKEEIEKLNSKPQKEEEN 1113

Query: 1035 AQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKE 1094
             +    +   + E   ++ +   ++ ++ + +++K+  + KQ  +E++ L     ++  E
Sbjct: 1114 EEKDKENDSEEGEENTSEKSHHKKHHKDLIGKLNKKNNEIKQLEKEIKGLKLTLSEKSNE 1173

Query: 1095 LKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQER 1154
            L   + T       +    +   +E + +    ++            +   ++++    +
Sbjct: 1174 LNNIRRTLAEKENNSNDETLQKKVEEIENLKKEINSLTESNENLKNLIDEMKKKDTTNNK 1233

Query: 1155 SVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDV-VNQEQINQLKSKLEQLNTENDNL 1213
            S    +  K     +E   K +     + +L   D  +N+EQ  Q     +++ TE    
Sbjct: 1234 SKTPVKFIKKAMSEKELSFKPMAQTVRSRDLNLTDFSLNEEQFRQEMESWKRIATER--- 1290

Query: 1214 LSTVAELRSSISSAVDQRGFEIAELWKQHLAQR----EADFQKTEHELRVQLSAFESKYE 1269
                A     +   ++ R  EI +L K+  +      + +  K E     Q + ++ K  
Sbjct: 1291 ----ARENDDLRQQINSRDQEIEKLKKEEKSTNFQISKMNNDKQELAKLRQDNTYKDKEI 1346

Query: 1270 QLLDSVQSSTQEETNKIVT-MEQVTSLQNKLQ----DKEEHLRNLQEKYADVINQIEILR 1324
            Q L S  SS + E NK+ T ++Q  +  NKL+     KE  ++ L++  +   N+I+ L+
Sbjct: 1347 QRLLSEASSKETENNKLKTELDQKNNECNKLKTLNNSKENDIKQLKQDLSHKDNEIQALK 1406

Query: 1325 SEIEDEK 1331
            +EI  ++
Sbjct: 1407 NEIHSKE 1413



 Score =  137 bits (332), Expect = 2e-30
 Identities = 216/1096 (19%), Positives = 484/1096 (44%), Gaps = 82/1096 (7%)

Query: 475  VNEIAKVQEQLKQELNDEIK-DVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNH 533
            +N +  + +QL     DE      V   I +L     ++++ N    A+N  +++   + 
Sbjct: 73   MNFLRTIADQLGITQQDEASLKCQVSTRIHELIKINGKMSKQNVSEVASNDPLVQNSDSE 132

Query: 534  KLKLKQM-QKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGR 592
              K + + +++ +N   V     EI +L +EL   + +   LEE     +  L D +   
Sbjct: 133  SSKSQDIAEESKENSKSVKQLEDEIKQLKQELDEQTNRADSLEEMNEKFRSLLPDSE--- 189

Query: 593  MIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQS 652
                D      ++++L E     I   +S++    +  H  +    ++ +K  +I QL+ 
Sbjct: 190  ----DFESAYSQLKSLCENSNSTIDDNDSEEKSHKKRHH--KDLIGKLNEKNNEIKQLEK 243

Query: 653  DQVCSEIKSVHLEEQIDALSASKKELALVIENLKLD------KEQLYGTIKDLENDKEDI 706
            +    ++       +++ +  +  E    IENL  +      +E L    +++E  KE+I
Sbjct: 244  EIKSLKLTLSERSNELNNIRRTLAEKEEEIENLNKNSSNSSNEEDLKKKDEEIEKLKEEI 303

Query: 707  MNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAK---IQERDLY 763
              KL +  Q+  +  +K ++  +E+  E  ++ +H ++        ++ K   I++ +  
Sbjct: 304  -EKLNSKPQKEEENEEKDKENDSEEGEENTSEKSHHKKHHKDLIGKLNKKNNEIKQLEKE 362

Query: 764  IENIESELSKYKSRICRLEESIAVMEDRRY--SLERKADQLGSYLQEKQKAYSEYTIQED 821
            I+ ++  LS+  + +  +  ++A  E+     +L++K +++ + L+++ + +   +  E+
Sbjct: 363  IKGLKLTLSERSNELNNIRRTLAEKENNSNDETLQKKVEEIEN-LKKEIEEFKNKSSNEE 421

Query: 822  ELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVE 881
            EL +           +EK   + + E    +K  +   EE +      S  ++H+  L+ 
Sbjct: 422  ELNSLRESNQKLKEEIEKLSNKPQKEEGNEEKDKENDSEEGEENTSEKSHHKKHHKDLIG 481

Query: 882  KANRTDLAESESTKYQTQLRDLESNLKRITHEHQTL---IVQKKKEIEDLEI-EFNTQIE 937
            K N+ +   +E  + + +++ L+  L   ++E   +   + +K++E+E+L+  E NTQ  
Sbjct: 482  KLNKKN---NEIKQLEKEIKSLKLTLSERSNELNNIRRTLAEKEQEMENLKNGEGNTQNN 538

Query: 938  SAIRDKKVLNEKYEKNIEYVT-QLE---AQLQEYKNNIENLNMNVEELNKMNLELIDKHV 993
              +   K  N K ++ +E +  QL+   A+L++ ++N  N +   EE  +MN +  D+  
Sbjct: 539  EELNQLKEDNNKQKEELESLKKQLQDKDAELEQIRSNT-NTSTITEESKEMNSDNDDEES 597

Query: 994  QKQQTQS--PDYTEQYINEINKLNALLKQKDEEIIALNQKIN---NAQVSYMSMVSDYES 1048
            +K Q++S    + +  I ++N+ N  +KQ ++EI +L   ++   N   +    +++ E 
Sbjct: 598  EKSQSKSGHKKHHKDLIGKLNQKNNEIKQLEKEIKSLKLTLSERSNELNNIRRTLTEKEQ 657

Query: 1049 KLAQFTTKLENM--EEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNI 1106
            ++        N   EE++++  +++   ++ N++LQ  +  +D++I++L       E N 
Sbjct: 658  EIDNLKKSGSNSSNEEDLKKKDEEIKSLRESNDKLQKELLTRDEEIEKLSNKPQKEEENE 717

Query: 1107 PKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKV--QEEEEFIQERSVLQEQSAKL 1164
             K +        E  S+ +++                   Q E+E    +  L E+S +L
Sbjct: 718  EKDKENDSEEGEENTSEKSHHKKHHKDLIGKLNKKNNEIKQLEKEIKGLKLTLSERSNEL 777

Query: 1165 NTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSI 1224
            N   +    K  ++E LN  +      N ++I +L+ + E+L +E  +  + + ++RS+ 
Sbjct: 778  NNIRRTLAEKEQEMENLNGSVQNK---NDDEIKELQQENEKLKSELASKDAELEQIRSNT 834

Query: 1225 SSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETN 1284
            +++       I E  K+  +  + D    E E     S  +  ++ L+  +     ++ N
Sbjct: 835  NTST------ITEESKEMNSDNDDD---EESEKSQSKSGHKKHHKDLIGKLN----QKNN 881

Query: 1285 KIVTME-QVTSLQNKLQDKEEHLRNLQEKYADVINQIE---ILRSEIEDEKVAFXXXXXX 1340
            +I  +E ++ SL+  L ++   L N++   A+  N      + + E E E +        
Sbjct: 882  EIKQLEKEIKSLKLTLSERSNELNNIRRTLAEKENNSNDETLQKKEEEIENLKKEIDNLK 941

Query: 1341 XXXXXXXXXXDLRTENQSYK-QMQEQSILNINEE--NAQLKKSSXXXXXXXXXXXXRVND 1397
                       LR E +  K +++ +  +N N    N ++   +            + + 
Sbjct: 942  KSSSNEEETKSLRDEIEKLKKELESKESMNTNTSTINEEIDGEAKENDSEEENTSEKSHH 1001

Query: 1398 AEAKVLELTHQLELKDSEIYQKTHEYT---ITLTQRNDEFENVRQQLVEYEKRIEDLTYE 1454
             +    +L  +L  K++EI Q   E     +TL++R++E  N+R+ L E E    D T +
Sbjct: 1002 KKHHK-DLIGKLNQKNNEIKQLEKEIKSLKLTLSERSNELNNIRRTLAEKENNSNDETLQ 1060

Query: 1455 KE-SELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESV-SLNKQVAELNKAL 1512
            K+  E+  L+ ++ E  N      K S  E +  + E N K+ E +  LN +  +  +  
Sbjct: 1061 KKVEEIENLKKEIEEFKN------KSSNEEELNSLRESNQKLKEEIEKLNSKPQKEEE-- 1112

Query: 1513 EEEVAKTNEMQTALEN 1528
             EE  K N+ +   EN
Sbjct: 1113 NEEKDKENDSEEGEEN 1128



 Score =  137 bits (332), Expect = 2e-30
 Identities = 261/1316 (19%), Positives = 556/1316 (42%), Gaps = 133/1316 (10%)

Query: 318  IANMTELTKKIELLEHLNCQIRQTNKEL---ENKLATMGTESKAVSSPSKKGSPLISRKS 374
            IA+   +T++ E    L CQ+     EL     K++       A + P  + S   S KS
Sbjct: 79   IADQLGITQQDEA--SLKCQVSTRIHELIKINGKMSKQNVSEVASNDPLVQNSDSESSKS 136

Query: 375  GRNTASKMKSPWS--QLSSET--LNQDTDKKINK-NEIAKLEMVIQSLNKDLVDKEYVIS 429
                    ++  S  QL  E   L Q+ D++ N+ + + ++    +SL  D  D E   S
Sbjct: 137  QDIAEESKENSKSVKQLEDEIKQLKQELDEQTNRADSLEEMNEKFRSLLPDSEDFESAYS 196

Query: 430  EKDTXXXXXXXXXXGKDT------------LIAQLQLEH----QQHMEGPSL-IHVGTNT 472
            +  +            D+            LI +L  ++    Q   E  SL + +   +
Sbjct: 197  QLKSLCENSNSTIDDNDSEEKSHKKRHHKDLIGKLNEKNNEIKQLEKEIKSLKLTLSERS 256

Query: 473  EDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSN 532
             ++N I +   + ++E+ +  K+ +     E LK  +E+I +L +EI+  N    K + N
Sbjct: 257  NELNNIRRTLAEKEEEIENLNKNSSNSSNEEDLKKKDEEIEKLKEEIEKLNSKPQKEEEN 316

Query: 533  -HKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSG 591
              K K    ++  +N S+ S   K    L  +L+  + ++ +LE+E   L+L L +  + 
Sbjct: 317  EEKDKENDSEEGEENTSEKSHHKKHHKDLIGKLNKKNNEIKQLEKEIKGLKLTLSERSN- 375

Query: 592  RMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQ 651
                        E+ N+  T    ++  E+   D       LQ+K +E+E+   +I + +
Sbjct: 376  ------------ELNNIRRT----LAEKENNSND-----ETLQKKVEEIENLKKEIEEFK 414

Query: 652  SDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGT-IKDLENDKEDIMNKL 710
            +       KS + EE++++L  S ++L   IE L    ++  G   KD END E+     
Sbjct: 415  N-------KSSN-EEELNSLRESNQKLKEEIEKLSNKPQKEEGNEEKDKENDSEE----- 461

Query: 711  QNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESE 770
                +EN       +K   + I +L  K N  +Q        ++ +I+   L +    +E
Sbjct: 462  ---GEENTSEKSHHKKHHKDLIGKLNKKNNEIKQ--------LEKEIKSLKLTLSERSNE 510

Query: 771  LSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVL 830
            L+  +  +   E+ +  +++   + +   ++L    ++  K       Q++EL +    L
Sbjct: 511  LNNIRRTLAEKEQEMENLKNGEGNTQNN-EELNQLKEDNNK-------QKEELESLKKQL 562

Query: 831  MDHDRVVEK-----QLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANR 885
             D D  +E+         I  E+KE+   N    EE++  Q S S  ++H+  L+ K N+
Sbjct: 563  QDKDAELEQIRSNTNTSTITEESKEMNSDNDD--EESEKSQ-SKSGHKKHHKDLIGKLNQ 619

Query: 886  TDLAESESTKYQTQLRDLESNLKRITHEHQTL---IVQKKKEIEDLEIE-FNTQIESAIR 941
             +   +E  + + +++ L+  L   ++E   +   + +K++EI++L+    N+  E  ++
Sbjct: 620  KN---NEIKQLEKEIKSLKLTLSERSNELNNIRRTLTEKEQEIDNLKKSGSNSSNEEDLK 676

Query: 942  DK----KVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQ 997
             K    K L E  +K  + +   + ++++  N  +    N EE +K N     +    ++
Sbjct: 677  KKDEEIKSLRESNDKLQKELLTRDEEIEKLSNKPQKEEEN-EEKDKENDSEEGEENTSEK 735

Query: 998  TQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKL 1057
            +    + +  I ++NK N  +KQ ++EI  L   ++       + +++    LA+   ++
Sbjct: 736  SHHKKHHKDLIGKLNKKNNEIKQLEKEIKGLKLTLSERS----NELNNIRRTLAEKEQEM 791

Query: 1058 ENMEEEMQ-RVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISS 1116
            EN+   +Q +   ++ + +Q NE+L+  +  +D ++++++    T  +   +++ M   +
Sbjct: 792  ENLNGSVQNKNDDEIKELQQENEKLKSELASKDAELEQIRSNTNTSTIT-EESKEMNSDN 850

Query: 1117 TIEPMSDDANNVDXXXXXXXXXXXXL--KVQEEEEFIQERSVLQEQSAKLNTELQECYTK 1174
              +  S+ + +              L  K  E ++  +E   L+   ++ + EL      
Sbjct: 851  DDDEESEKSQSKSGHKKHHKDLIGKLNQKNNEIKQLEKEIKSLKLTLSERSNELNNIRRT 910

Query: 1175 IIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFE 1234
            + + E  + + T      +E+I  LK +++ L   + N   T   LR  I     +   +
Sbjct: 911  LAEKENNSNDETLQK--KEEEIENLKKEIDNLKKSSSNEEET-KSLRDEIEKLKKELESK 967

Query: 1235 IAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTME-QVT 1293
             +          E D +  E++   + ++ +S +++    +     ++ N+I  +E ++ 
Sbjct: 968  ESMNTNTSTINEEIDGEAKENDSEEENTSEKSHHKKHHKDLIGKLNQKNNEIKQLEKEIK 1027

Query: 1294 SLQNKLQDKEEHLRNLQEKYADVINQI--EILRSEIED-EKVAFXXXXXXXXXXXXXXXX 1350
            SL+  L ++   L N++   A+  N    E L+ ++E+ E +                  
Sbjct: 1028 SLKLTLSERSNELNNIRRTLAEKENNSNDETLQKKVEEIENLKKEIEEFKNKSSNEEELN 1087

Query: 1351 DLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLE 1410
             LR  NQ  K+  E+      +E    +K                +  +    +L  +L 
Sbjct: 1088 SLRESNQKLKEEIEKLNSKPQKEEENEEKDKENDSEEGEENTSEKSHHKKHHKDLIGKLN 1147

Query: 1411 LKDSEIYQKTHE---YTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMH 1467
             K++EI Q   E     +TL+++++E  N+R+ L E E    D T +K+ E  I  LK  
Sbjct: 1148 KKNNEIKQLEKEIKGLKLTLSEKSNELNNIRRTLAEKENNSNDETLQKKVE-EIENLKKE 1206

Query: 1468 ENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALE 1527
             N+        ES      LI+E+  K T +      V  + KA+ E+      M   + 
Sbjct: 1207 INS------LTESNENLKNLIDEMKKKDTTNNKSKTPVKFIKKAMSEKELSFKPMAQTVR 1260

Query: 1528 NQEIEIV--TLNDE--ITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKE 1579
            ++++ +   +LN+E     +++  R ++ + +++          RD++++    +E
Sbjct: 1261 SRDLNLTDFSLNEEQFRQEMESWKRIATERARENDDLRQQI-NSRDQEIEKLKKEE 1315



 Score =  127 bits (307), Expect = 2e-27
 Identities = 253/1206 (20%), Positives = 523/1206 (43%), Gaps = 138/1206 (11%)

Query: 356  SKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQ 415
            +K  SS S+  SP  S ++   ++ +   P SQ  SE    D      +N+  +LE+++ 
Sbjct: 17   TKRKSSGSEGFSPKQSSENESYSSQQDNQPESQ--SEQNVPDVCSDSERNDSQRLEILMN 74

Query: 416  SLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPS---LIH----V 468
             L + + D +  I+++D             + +    ++  Q   E  S   L+      
Sbjct: 75   FL-RTIAD-QLGITQQDEASLKCQVSTRIHELIKINGKMSKQNVSEVASNDPLVQNSDSE 132

Query: 469  GTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAA---NKN 525
             + ++D+ E +K   +  ++L DEIK   +K  +++  +  + + ++N++  +    +++
Sbjct: 133  SSKSQDIAEESKENSKSVKQLEDEIK--QLKQELDEQTNRADSLEEMNEKFRSLLPDSED 190

Query: 526  MIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVR--LTEELHHLSQKVAELEEEKGNLQL 583
                 S  K   +    TID+      S+K+     L  +L+  + ++ +LE+E  +L+L
Sbjct: 191  FESAYSQLKSLCENSNSTIDDNDSEEKSHKKRHHKDLIGKLNEKNNEIKQLEKEIKSLKL 250

Query: 584  HLVDYDSG-RMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVED 642
             L +  +    I   + +K  E+ENL +    + +  + +K D  +E+  L+++ +++  
Sbjct: 251  TLSERSNELNNIRRTLAEKEEEIENLNKNSSNSSNEEDLKKKD--EEIEKLKEEIEKLNS 308

Query: 643  KLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLEND 702
            K     + ++++   E  S   EE     S  KK    +I   KL+K+     IK LE +
Sbjct: 309  K--PQKEEENEEKDKENDSEEGEENTSEKSHHKKHHKDLIG--KLNKKN--NEIKQLEKE 362

Query: 703  KEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDL 762
                +  L+  + E  +  + + +  AEK          E  S  +T   +  K++E   
Sbjct: 363  ----IKGLKLTLSERSNELNNIRRTLAEK----------ENNSNDET---LQKKVEE--- 402

Query: 763  YIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDE 822
             IEN++ E+ ++K++    EE +  + +    L+ + ++L +  Q+++    +    + E
Sbjct: 403  -IENLKKEIEEFKNKSSN-EEELNSLRESNQKLKEEIEKLSNKPQKEEGNEEKDKENDSE 460

Query: 823  LVNRLAVLMDHDRVVEKQLL-EIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVE 881
                      H +   K L+ ++  +N E+++    L +E ++L+++LS+     N +  
Sbjct: 461  EGEENTSEKSHHKKHHKDLIGKLNKKNNEIKQ----LEKEIKSLKLTLSERSNELNNI-- 514

Query: 882  KANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIR 941
               R  LAE E        +++E NLK    E  T   Q  +E+  L+ + N Q E    
Sbjct: 515  ---RRTLAEKE--------QEME-NLK--NGEGNT---QNNEELNQLKEDNNKQKEELES 557

Query: 942  DKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSP 1001
             KK L +K           +A+L++ ++N  N +   EE  +MN +  D+  +K Q++S 
Sbjct: 558  LKKQLQDK-----------DAELEQIRSN-TNTSTITEESKEMNSDNDDEESEKSQSKS- 604

Query: 1002 DYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENME 1061
             + + + + I KLN    QK+ EI  L ++I + +++    +S+  ++L      L   E
Sbjct: 605  GHKKHHKDLIGKLN----QKNNEIKQLEKEIKSLKLT----LSERSNELNNIRRTLTEKE 656

Query: 1062 EEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPM 1121
            +E+  + K    S   NEE    ++++D++IK L+E+    +  +   +  I   + +P 
Sbjct: 657  QEIDNLKKS--GSNSSNEE---DLKKKDEEIKSLRESNDKLQKELLTRDEEIEKLSNKPQ 711

Query: 1122 SDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETL 1181
             ++ N                  +E EE   E+S  ++    L  +L +   +I QLE  
Sbjct: 712  KEEENEEKDKENDS---------EEGEENTSEKSHHKKHHKDLIGKLNKKNNEIKQLE-- 760

Query: 1182 NTELTGHDVVNQE---QINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAEL 1238
              E+ G  +   E   ++N ++  L +   E +NL  +V          + Q      E 
Sbjct: 761  -KEIKGLKLTLSERSNELNNIRRTLAEKEQEMENLNGSVQNKNDDEIKELQQEN----EK 815

Query: 1239 WKQHLAQREADFQKTEHELRVQLSAFESKY-------EQLLDSVQSSTQEETNKIVTMEQ 1291
             K  LA ++A+ ++            ESK        ++  +  QS +  + +    + +
Sbjct: 816  LKSELASKDAELEQIRSNTNTSTITEESKEMNSDNDDDEESEKSQSKSGHKKHHKDLIGK 875

Query: 1292 VTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXD 1351
            +    N+++  E+ +++L+   ++  N++  +R  +  EK                    
Sbjct: 876  LNQKNNEIKQLEKEIKSLKLTLSERSNELNNIRRTLA-EKENNSNDETLQKKEEEIENLK 934

Query: 1352 LRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLEL 1411
               +N       E+   ++ +E  +LKK                 + + +  E   + E 
Sbjct: 935  KEIDNLKKSSSNEEETKSLRDEIEKLKKELESKESMNTNTSTINEEIDGEAKENDSEEEN 994

Query: 1412 KDSEIYQKTHEYTI--TLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILR--LKMH 1467
               + + K H   +   L Q+N+E + + +++    K ++    E+ +EL  +R  L   
Sbjct: 995  TSEKSHHKKHHKDLIGKLNQKNNEIKQLEKEI----KSLKLTLSERSNELNNIRRTLAEK 1050

Query: 1468 ENANHYETMQKE-SEIERVKL-IEELNVKITESVSLNKQVAELNKALEEEVAKTN-EMQT 1524
            EN ++ ET+QK+  EIE +K  IEE   K +    LN  + E N+ L+EE+ K N + Q 
Sbjct: 1051 ENNSNDETLQKKVEEIENLKKEIEEFKNKSSNEEELN-SLRESNQKLKEEIEKLNSKPQK 1109

Query: 1525 ALENQE 1530
              EN+E
Sbjct: 1110 EEENEE 1115



 Score =  122 bits (295), Expect = 6e-26
 Identities = 259/1240 (20%), Positives = 507/1240 (40%), Gaps = 153/1240 (12%)

Query: 143  DVTHLSNTIKEKDNALSVLQVKMKIMETTILD--LQEKINE----KDQIIEAKNKATTXX 196
            ++  L  T+ E+ N L+ ++  +   E    D  LQ+K+ E    K +I E KNK++   
Sbjct: 362  EIKGLKLTLSERSNELNNIRRTLAEKENNSNDETLQKKVEEIENLKKEIEEFKNKSSNEE 421

Query: 197  XXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEA 256
                           +  K+++ K+       E   + +K+   ++ E      S  ++ 
Sbjct: 422  ELNSLRESN------QKLKEEIEKLSNKPQKEEGNEEKDKENDSEEGEENTSEKSHHKKH 475

Query: 257  NKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSL 316
            +K L     + + E  +L +E++               + +   E   E++ E  + G  
Sbjct: 476  HKDLIGKLNKKNNEIKQLEKEIKSLKLTLSERSNELNNIRRTLAEK--EQEMENLKNGEG 533

Query: 317  EIANMTELT-------KKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPL 369
               N  EL        K+ E LE L  Q++  + ELE       T +  ++  SK+    
Sbjct: 534  NTQNNEELNQLKEDNNKQKEELESLKKQLQDKDAELEQ--IRSNTNTSTITEESKE---- 587

Query: 370  ISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINK--NEIAKLEMVIQSLNKDLVDKEYV 427
                +  N   + +   S+   +  ++D   K+N+  NEI +LE  I+SL   L ++   
Sbjct: 588  ---MNSDNDDEESEKSQSKSGHKKHHKDLIGKLNQKNNEIKQLEKEIKSLKLTLSERSNE 644

Query: 428  ISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLK- 486
            ++                   I +   E +Q ++  +L   G+N+ +  ++ K  E++K 
Sbjct: 645  LNN------------------IRRTLTEKEQEID--NLKKSGSNSSNEEDLKKKDEEIKS 684

Query: 487  -QELNDEI-KDVNVKDL-IEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKT 543
             +E ND++ K++  +D  IEKL S + Q  + N+E D  N +  + + N   K    +  
Sbjct: 685  LRESNDKLQKELLTRDEEIEKL-SNKPQKEEENEEKDKENDSE-EGEENTSEKSHHKKHH 742

Query: 544  IDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSG-RMIESDVYKKM 602
             D   K++  N EI +L +E+  L   ++E   E  N++  L + +     +   V  K 
Sbjct: 743  KDLIGKLNKKNNEIKQLEKEIKGLKLTLSERSNELNNIRRTLAEKEQEMENLNGSVQNKN 802

Query: 603  I-EMENLAETRLKAISLLESQKFDLVQ-----ELHILQQKYDEVEDKLADISQLQSDQVC 656
              E++ L +   K  S L S+  +L Q         + ++  E+     D  + +  Q  
Sbjct: 803  DDEIKELQQENEKLKSELASKDAELEQIRSNTNTSTITEESKEMNSDNDDDEESEKSQSK 862

Query: 657  SEIKSVHLE---------EQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKED-I 706
            S  K  H +          +I  L    K L L +     +   +  T+ + EN+  D  
Sbjct: 863  SGHKKHHKDLIGKLNQKNNEIKQLEKEIKSLKLTLSERSNELNNIRRTLAEKENNSNDET 922

Query: 707  MNKLQNYIQENMDLTDKLEKMSAEK-----ISELLAKINHEEQSK--IQTQFG-----ID 754
            + K +  I+      D L+K S+ +     + + + K+  E +SK  + T        ID
Sbjct: 923  LQKKEEEIENLKKEIDNLKKSSSNEEETKSLRDEIEKLKKELESKESMNTNTSTINEEID 982

Query: 755  AKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYS 814
             + +E D   EN  SE S +K     L   +    +    LE++   L   L E+    +
Sbjct: 983  GEAKENDSEEENT-SEKSHHKKHHKDLIGKLNQKNNEIKQLEKEIKSLKLTLSERSNELN 1041

Query: 815  EYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQK-KNQILLEENQNLQISLSDMQ 873
                   E  N       +D  ++K++ EIE+  KE+++ KN+   EE  N   SL +  
Sbjct: 1042 NIRRTLAEKENN-----SNDETLQKKVEEIENLKKEIEEFKNKSSNEEELN---SLRESN 1093

Query: 874  QHYNALVEKANRTDLAESESTKY--QTQLRDLESNLKRITHE---HQTLIVQKKKEIEDL 928
            Q     +EK N     E E+ +   +    + E N    +H    H+ LI +  K+  ++
Sbjct: 1094 QKLKEEIEKLNSKPQKEEENEEKDKENDSEEGEENTSEKSHHKKHHKDLIGKLNKKNNEI 1153

Query: 929  EIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLEL 988
            +     Q+E  I+  K+   +    +  + +  A+ +E  +N E L   VEE+  +  E+
Sbjct: 1154 K-----QLEKEIKGLKLTLSEKSNELNNIRRTLAE-KENNSNDETLQKKVEEIENLKKEI 1207

Query: 989  IDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYES 1048
                     T+S +  +  I+E+ K +    +    +  + + ++  ++S+  M     S
Sbjct: 1208 ------NSLTESNENLKNLIDEMKKKDTTNNKSKTPVKFIKKAMSEKELSFKPMAQTVRS 1261

Query: 1049 K---LAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMN 1105
            +   L  F+   E   +EM+   +   +  + N++L+  +  +D +I++LK+ + +    
Sbjct: 1262 RDLNLTDFSLNEEQFRQEMESWKRIATERARENDDLRQQINSRDQEIEKLKKEEKSTNFQ 1321

Query: 1106 IPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLN 1165
            I K                  N D             K +E +  + E S  + ++ KL 
Sbjct: 1322 ISKM-----------------NNDKQELAKLRQDNTYKDKEIQRLLSEASSKETENNKLK 1364

Query: 1166 TELQECYTKIIQLETLNT-----------ELTGHDVVNQEQINQLKSK-LEQLNTENDNL 1213
            TEL +   +  +L+TLN            +L+  D   Q   N++ SK  E +  +N+ L
Sbjct: 1365 TELDQKNNECNKLKTLNNSKENDIKQLKQDLSHKDNEIQALKNEIHSKENEIIKVKNEGL 1424

Query: 1214 LSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLD 1273
            +++V +L+  +++    +   + E  K H ++        E + R +     +K ++ L 
Sbjct: 1425 MNSVTQLQRKVAALTTDKTM-LTEEVKLHTSR--LSVLAAERKSREEEEQLMAKLKRRLI 1481

Query: 1274 SVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRN-LQEK 1312
            +     QE+  +   +E + S   KL+ + E L N L+EK
Sbjct: 1482 AKDVELQEKDRQ---LEFLNSSVKKLKKENEQLNNELKEK 1518



 Score =  118 bits (285), Expect = 1e-24
 Identities = 243/1228 (19%), Positives = 519/1228 (42%), Gaps = 128/1228 (10%)

Query: 55   ERAQKCLENAALVSKRIKEHRKATAELLGRPFVPGISESLANTLKQKEILMEKIKQYKEL 114
            E  QK +E    + K I+E +  ++       +   ++ L   +++     +K +  +E 
Sbjct: 394  ETLQKKVEEIENLKKEIEEFKNKSSNEEELNSLRESNQKLKEEIEKLSNKPQKEEGNEEK 453

Query: 115  SKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNALSVLQVKMKIMETTILD 174
             K + +                    +G +   +N IK+ +  +  L++ +      + +
Sbjct: 454  DKENDSEEGEENTSEKSHHKKHHKDLIGKLNKKNNEIKQLEKEIKSLKLTLSERSNELNN 513

Query: 175  LQEKINEKDQIIE-AKN-KATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEW 232
            ++  + EK+Q +E  KN +  T                 E+ +    ++Q+    +E   
Sbjct: 514  IRRTLAEKEQEMENLKNGEGNTQNNEELNQLKEDNNKQKEELESLKKQLQDKDAELEQIR 573

Query: 233  KDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHS---KLAQELEQXXXXXXXXX 289
             +     + + ESK++   + +E ++  ++             KL Q+  +         
Sbjct: 574  SNTNTSTITE-ESKEMNSDNDDEESEKSQSKSGHKKHHKDLIGKLNQKNNEIKQLEKEIK 632

Query: 290  XXXXXLAKQSIEPS------CEEKTEIE--EKGSLEIANMTELTKKIELLEHLNCQIRQT 341
                 L+++S E +       E++ EI+  +K     +N  +L KK E ++ L    R++
Sbjct: 633  SLKLTLSERSNELNNIRRTLTEKEQEIDNLKKSGSNSSNEEDLKKKDEEIKSL----RES 688

Query: 342  NKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLN-QDTDK 400
            N +L+ +L T   E + +S+  +K       K   N + + +   S+ S    + +D   
Sbjct: 689  NDKLQKELLTRDEEIEKLSNKPQKEEEN-EEKDKENDSEEGEENTSEKSHHKKHHKDLIG 747

Query: 401  KINK--NEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQ 458
            K+NK  NEI +LE  I+ L   L ++   ++                   I +   E +Q
Sbjct: 748  KLNKKNNEIKQLEKEIKGLKLTLSERSNELNN------------------IRRTLAEKEQ 789

Query: 459  HMEGPSLIHVGTNTEDVNEIAKVQEQLKQEL---NDEIKDVNVKDLIEKLKSAEEQITQL 515
             ME  +      N +++ E+ +  E+LK EL   + E++ +        +    +++   
Sbjct: 790  EMENLNGSVQNKNDDEIKELQQENEKLKSELASKDAELEQIRSNTNTSTITEESKEMNSD 849

Query: 516  NDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELE 575
            ND+ + + K+  + KS HK   K      D   K++  N EI +L +E+  L   ++E  
Sbjct: 850  NDDDEESEKS--QSKSGHKKHHK------DLIGKLNQKNNEIKQLEKEIKSLKLTLSERS 901

Query: 576  EEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAET--RLKAISLLESQKFDLVQELHIL 633
             E  N++  L + ++    E+ + KK  E+ENL +    LK  S  E +   L  E+  L
Sbjct: 902  NELNNIRRTLAEKENNSNDET-LQKKEEEIENLKKEIDNLKKSSSNEEETKSLRDEIEKL 960

Query: 634  QQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLY 693
            +++ +  E    + S + ++++  E K    EE+    + S+K       + K   + L 
Sbjct: 961  KKELESKESMNTNTSTI-NEEIDGEAKENDSEEE----NTSEKS------HHKKHHKDLI 1009

Query: 694  GTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGI 753
            G +    N K + + +L+  I+ ++ LT          I   LA+   E  S  +T   +
Sbjct: 1010 GKL----NQKNNEIKQLEKEIK-SLKLTLSERSNELNNIRRTLAE--KENNSNDET---L 1059

Query: 754  DAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAY 813
              K++E    IEN++ E+ ++K++    EE +  + +    L+ + ++L S  Q++++  
Sbjct: 1060 QKKVEE----IENLKKEIEEFKNKSSN-EEELNSLRESNQKLKEEIEKLNSKPQKEEENE 1114

Query: 814  SEYTIQEDELVNRLAVLMDHDRVVEKQLL-EIEHENKELQKKNQILLEENQNLQISLSDM 872
             +    + E          H +   K L+ ++  +N E+++    L +E + L+++LS+ 
Sbjct: 1115 EKDKENDSEEGEENTSEKSHHKKHHKDLIGKLNKKNNEIKQ----LEKEIKGLKLTLSEK 1170

Query: 873  QQHYN----ALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTL--IVQKKKEIE 926
                N     L EK N ++  +    K   ++ +L+  +  +T  ++ L  ++ + K+ +
Sbjct: 1171 SNELNNIRRTLAEKENNSN--DETLQKKVEEIENLKKEINSLTESNENLKNLIDEMKKKD 1228

Query: 927  DLEIEFNTQIESAIRDKKVLNEK---YEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNK 983
                +  T ++     KK ++EK   ++   + V   +  L ++  N E     +E   +
Sbjct: 1229 TTNNKSKTPVKFI---KKAMSEKELSFKPMAQTVRSRDLNLTDFSLNEEQFRQEMESWKR 1285

Query: 984  MNLELIDKHVQ-KQQTQSPDYTEQYINEINKLN----ALLKQKDEEIIALNQKINNAQVS 1038
            +  E   ++   +QQ  S D   + + +  K      + +    +E+  L Q        
Sbjct: 1286 IATERARENDDLRQQINSRDQEIEKLKKEEKSTNFQISKMNNDKQELAKLRQDNTYKDKE 1345

Query: 1039 YMSMVSDYESKLAQ---FTTKLENMEEEMQRVSKQLLDSKQHN-EELQILVREQDDQIKE 1094
               ++S+  SK  +     T+L+    E  ++ K L +SK+++ ++L+  +  +D++I+ 
Sbjct: 1346 IQRLLSEASSKETENNKLKTELDQKNNECNKL-KTLNNSKENDIKQLKQDLSHKDNEIQA 1404

Query: 1095 LKETKLTFEMNI--PKTEGMIISST-----IEPMSDD----ANNVDXXXXXXXXXXXXLK 1143
            LK    + E  I   K EG++ S T     +  ++ D       V              K
Sbjct: 1405 LKNEIHSKENEIIKVKNEGLMNSVTQLQRKVAALTTDKTMLTEEVKLHTSRLSVLAAERK 1464

Query: 1144 VQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSK- 1202
             +EEEE +  +  L+ +    + ELQE   K  QLE LN+ +      N++  N+LK K 
Sbjct: 1465 SREEEEQLMAK--LKRRLIAKDVELQE---KDRQLEFLNSSVKKLKKENEQLNNELKEKN 1519

Query: 1203 --LEQLNTENDNLLSTVAELRSSISSAV 1228
              L QL+  +++ + T+   +++  S +
Sbjct: 1520 LRLSQLDNVHESAIRTMRRRQATKKSGI 1547


>UniRef50_Q23PQ6 Cluster: Putative uncharacterized protein; n=1;
            Tetrahymena thermophila SB210|Rep: Putative
            uncharacterized protein - Tetrahymena thermophila SB210
          Length = 2269

 Score =  142 bits (343), Expect = 9e-32
 Identities = 226/1294 (17%), Positives = 545/1294 (42%), Gaps = 99/1294 (7%)

Query: 337  QIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSG---RNTASKMKSPWSQLSSET 393
            QI +TN+EL  +       +  ++        ++ +++    +N + ++++   + S + 
Sbjct: 351  QIIRTNQELSEQFDNNSNFNTDLNERILDRKVILQKQNKLEKKNKSLRVENIELKNSLKV 410

Query: 394  LNQDTDKKINKNEIAKL--EMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQ 451
             N +T K   K E+ K   +++   LN++  +K+ +    D            K   I Q
Sbjct: 411  FNNETSKLEKKLEVEKKNNKLLNDILNQEFSEKQLIAQLNDIIENQKQEISELKID-IEQ 469

Query: 452  LQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQ 511
            LQ++     +    I    N++D +E+    +Q +    D+ K   +K +I+   S  E+
Sbjct: 470  LQIKVDNSKQEFEYIKSNPNSQDFDEMENEYDQAEALKQDQWK---IK-IIQAKSSVLEE 525

Query: 512  ITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKV 571
              Q+  +     + +  ++   ++  +Q Q   +  +++ +  K + +  ++    + K+
Sbjct: 526  KQQMESQKKDIEEKLRLIEEEKEVIYRQNQNYQNENTQLKNCYKTVEKQFKDAVKENDKL 585

Query: 572  AELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELH 631
             + ++E    Q  L + +              + + L E +L+ +  L  Q  D+ Q+L 
Sbjct: 586  KKKQQEFEEKQKRLEELEQ-------------QSQQLQE-QLQELEELRKQNEDIQQQLI 631

Query: 632  ILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQ 691
              ++   E+E +L+ + QL S+   ++  +  +EE  + L A K       E L+ D ++
Sbjct: 632  SEKKSRLEIETQLSSLRQLDSNNPSAQ--NSFIEEDKEQLLAEK-------EKLEEDLKE 682

Query: 692  LYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQF 751
               T  ++E  K     +  ++ Q+   +  +L+K   EK +      N ++    Q Q 
Sbjct: 683  ALRTKSEIELQKASFQTENASFRQQYKKIEKQLKKSIKEKEALKKELENEKKLFAEQLQS 742

Query: 752  GIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQK 811
            G    I++    ++  + E  +++ R  +LE  +  ++  + ++E+        ++EK  
Sbjct: 743  GEAKVIEQLKQELKQTKEERDEFQKRSSKLENKLKSLQQEQ-NMEKMETDFDKQIEEKIN 801

Query: 812  AYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSD 871
            A     I+E +      VL      ++K+L E   E   +++K+Q +L ENQN Q +LS 
Sbjct: 802  AAKSQVIEEKQ------VLEAEKEDIQKKLEETNREKLLIERKSQAVLSENQNFQQTLSS 855

Query: 872  MQQHYN-ALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEI 930
            +Q+    A+ E+ +  +   S   K+  ++  +E    +  ++ +    ++++E   L  
Sbjct: 856  LQKELKVAIKERDSIKNEVTSLRNKFAKKVELIEKLKTKFGYQEEEDQEEEEQEDPKLMH 915

Query: 931  EFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYK--NNIENLNMNVEELNKMNLEL 988
            + N ++   +     L E+ E  I+ + + ++++ E +  ++++ L    +E N    EL
Sbjct: 916  QHNREVRDLLTQIDQLKEEKEDLIQQIKEKQSKIDELQSDSSMQKLEEEYDEENSNKTEL 975

Query: 989  ---IDKHVQKQ---QTQSPDYTEQYINEINKLNALLKQKDE---EIIALNQKINNA---- 1035
               ID  V+++   + ++  Y + Y N   +    +KQ DE   ++    QKI+      
Sbjct: 976  QVQIDNLVKQKSRVEIENNYYKDTYKNVEKEFKKSVKQNDELKKKLAEAEQKISQLEKKV 1035

Query: 1036 ---------QVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVR 1086
                     +     + S  ++++ +   +LE ++ E + +  +L      N++LQ  + 
Sbjct: 1036 PKEDQEEGDEEEQQQIESSAQAEINELKQQLEKVKNENKNLKNELNSITDSNKDLQKAIE 1095

Query: 1087 E--QDDQIKELKE--TKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXL 1142
            +  ++ QIK L+        E  + K + M I   +  +  +   +             L
Sbjct: 1096 DAREEQQIKRLENEYDNQPDEDKLEKAKSMFIQEKL-VLEIEKEEIANQLSQKLSELDSL 1154

Query: 1143 KVQEEEEFIQERSVLQ----------EQSAKLNTELQECYTKIIQLETLNTELTGHDVVN 1192
            + +  ++ + E + L+          +++ K N EL++ + K   +ET N ++     + 
Sbjct: 1155 Q-KSSQQIVLENNGLKSTFKSFEKEFKRTVKENDELKKSFKK---METENQKIKDQVAMY 1210

Query: 1193 QEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQK 1252
            ++Q+  + +  E    E+ + +    +     S+  DQ   E+ +  K +L  +E +  K
Sbjct: 1211 KQQLGIVDTPTED-QEEDQSPVQNKHQQPLKQSNHSDQEFNELQD--KYNLMVKEFEEFK 1267

Query: 1253 TEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEK 1312
             EHE+  Q+  F+ K   L  +     Q E  K     +  SL  +    ++    L+++
Sbjct: 1268 KEHEM--QIMEFQEKEVYLQKTKTEIEQIEWEKSDLERKANSLSQEQSTHKQFYVTLEKQ 1325

Query: 1313 YADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTEN--QSYKQMQEQSILNI 1370
            +   + +I+ LR +  D+ V +                 L  +N  +  K +    ++ +
Sbjct: 1326 FKKSVKEIDNLRKD-NDKLVKYKERLSELVSQVIKKQEPLDEQNGDEEDKLLTVNPLVEL 1384

Query: 1371 NEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQR 1430
              + A L++ +            + N      ++  +    + SE+ ++           
Sbjct: 1385 TRQKAMLEQKNSYLTEQLEEMSKQNNQPSPAYVQQNNDNGAEVSELTEQLQNEQNENKSL 1444

Query: 1431 NDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEE 1490
              +   +  Q  + +   +D   E E++L  ++LK+ E        +K+   E +  +++
Sbjct: 1445 KAQIRTIEDQYQQKDSEQKDKIAELETQLQEIKLKLQEKDQKVNEKEKKLN-ELLGQLDQ 1503

Query: 1491 LNVKITESVSLNKQVAELNKALEEEVAKTNEMQ-----TALENQEIE-IVTLNDEITNLQ 1544
             N +I +  +  +Q  + NK L ++  +  E+Q       L+N+ +E     N+ + N  
Sbjct: 1504 QNQEIKKQYTFIQQSQQNNKELAKKNQEIEELQLQVKDLILDNKIVEQYKQQNEMLKNKC 1563

Query: 1545 NMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNK 1578
             ++ +S ++IQ+  +   +  + ++ +++  +N+
Sbjct: 1564 EILESSLTEIQEKKNQLINKIKDKESKIEVELNQ 1597



 Score =  128 bits (310), Expect = 9e-28
 Identities = 222/1103 (20%), Positives = 474/1103 (42%), Gaps = 102/1103 (9%)

Query: 490  NDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIK-VKSNHKL----KLKQMQKTI 544
            +DEI      D  EK  + EEQI QL +E      NM K +K ++ L     L+Q Q + 
Sbjct: 286  SDEILSSKSLDDDEKKYNLEEQIEQLKEE------NMFKQIKIDNLLVQLGALEQKQSSF 339

Query: 545  DNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIE 604
            D      D   +I+R  +EL       +E  +   N    L    + R+++    K +++
Sbjct: 340  DYQDAKIDELMQIIRTNQEL-------SEQFDNNSNFNTDL----NERILDR---KVILQ 385

Query: 605  MENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKL---ADISQLQSDQVCSEIKS 661
             +N  E + K+   L  +  +L   L +   +  ++E KL      ++L +D +  E   
Sbjct: 386  KQNKLEKKNKS---LRVENIELKNSLKVFNNETSKLEKKLEVEKKNNKLLNDILNQEFSE 442

Query: 662  VHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLT 721
              L  Q++ +  ++K+    I  LK+D EQL   IK ++N K++       YI+ N +  
Sbjct: 443  KQLIAQLNDIIENQKQ---EISELKIDIEQL--QIK-VDNSKQEF-----EYIKSNPNSQ 491

Query: 722  DKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRL 781
            D  ++M  E      A+   ++Q KI+      + ++E+    + +ES+    + ++  +
Sbjct: 492  D-FDEMENEYDQ---AEALKQDQWKIKIIQAKSSVLEEK----QQMESQKKDIEEKLRLI 543

Query: 782  EESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQL 841
            EE   V+  +  + + +  QL +  +  +K + +   + D+L  +     +     +K+L
Sbjct: 544  EEEKEVIYRQNQNYQNENTQLKNCYKTVEKQFKDAVKENDKLKKKQQEFEEK----QKRL 599

Query: 842  LEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLR 901
             E+E ++++LQ++    L+E + L+    D+QQ    + EK +R ++    S+  Q    
Sbjct: 600  EELEQQSQQLQEQ----LQELEELRKQNEDIQQ--QLISEKKSRLEIETQLSSLRQLDSN 653

Query: 902  DLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLE 961
            +  +    I  + + L+ +K+K  EDL+    T+ E  ++      E      +Y  ++E
Sbjct: 654  NPSAQNSFIEEDKEQLLAEKEKLEEDLKEALRTKSEIELQKASFQTENASFRQQY-KKIE 712

Query: 962  AQLQEYKNNIENLNMNVEELNKMNLELI---DKHVQKQQTQSPDYTEQYINEINKLNALL 1018
             QL++     E L   +E   K+  E +   +  V +Q  Q    T++  +E  K ++ L
Sbjct: 713  KQLKKSIKEKEALKKELENEKKLFAEQLQSGEAKVIEQLKQELKQTKEERDEFQKRSSKL 772

Query: 1019 KQKDEEIIALNQKINNAQVSYMSMVSD-YESKLAQFTTKLENMEEEMQRVSKQLLDSKQH 1077
            + K +  +   Q +   +  +   + +   +  +Q   + + +E E + + K+L   ++ 
Sbjct: 773  ENKLKS-LQQEQNMEKMETDFDKQIEEKINAAKSQVIEEKQVLEAEKEDIQKKL---EET 828

Query: 1078 NEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXX 1137
            N E  ++ R+    + E +  + T   ++ K   + I    + + ++  ++         
Sbjct: 829  NREKLLIERKSQAVLSENQNFQQTLS-SLQKELKVAIKER-DSIKNEVTSLRNKFAKKVE 886

Query: 1138 XXXXLKV----QEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQ 1193
                LK     QEEE+  +E     +   + N E+++  T+I QL+    +L       Q
Sbjct: 887  LIEKLKTKFGYQEEEDQEEEEQEDPKLMHQHNREVRDLLTQIDQLKEEKEDLIQQIKEKQ 946

Query: 1194 EQINQLK--SKLEQLNTENDNLLSTVAELRSSISSAVDQRG-FEIA-ELWKQHLAQREAD 1249
             +I++L+  S +++L  E D   S   EL+  I + V Q+   EI    +K      E +
Sbjct: 947  SKIDELQSDSSMQKLEEEYDEENSNKTELQVQIDNLVKQKSRVEIENNYYKDTYKNVEKE 1006

Query: 1250 FQKT---EHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHL 1306
            F+K+     EL+ +L+  E K  QL   V    QEE ++    +  +S Q ++ + ++ L
Sbjct: 1007 FKKSVKQNDELKKKLAEAEQKISQLEKKVPKEDQEEGDEEEQQQIESSAQAEINELKQQL 1066

Query: 1307 RNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQ----- 1361
              ++ +  ++ N++  +    +D + A                 D + +    ++     
Sbjct: 1067 EKVKNENKNLKNELNSITDSNKDLQKAIEDAREEQQIKRLENEYDNQPDEDKLEKAKSMF 1126

Query: 1362 MQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQ-LELKDSEIYQKT 1420
            +QE+ +L I +E    + S             +    E   L+ T +  E +     ++ 
Sbjct: 1127 IQEKLVLEIEKEEIANQLSQKLSELDSLQKSSQQIVLENNGLKSTFKSFEKEFKRTVKEN 1186

Query: 1421 HEYTITLTQRNDEFENVRQQLVEYEKR---IEDLTYEKESELAILRLKMHENANHYETMQ 1477
             E   +  +   E + ++ Q+  Y+++   ++  T ++E + + ++ K      H + ++
Sbjct: 1187 DELKKSFKKMETENQKIKDQVAMYKQQLGIVDTPTEDQEEDQSPVQNK------HQQPLK 1240

Query: 1478 KESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLN 1537
            + +  ++     EL  K    V   K+  E  K  E ++ +  E +  L+  + EI  + 
Sbjct: 1241 QSNHSDQE--FNELQDKYNLMV---KEFEEFKKEHEMQIMEFQEKEVYLQKTKTEIEQIE 1295

Query: 1538 DEITNLQNMVRASSSKIQKHVSF 1560
             E ++L+    + S +   H  F
Sbjct: 1296 WEKSDLERKANSLSQEQSTHKQF 1318



 Score =  128 bits (309), Expect = 1e-27
 Identities = 228/1161 (19%), Positives = 495/1161 (42%), Gaps = 94/1161 (8%)

Query: 212  EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271
            E  KQ   K++   I  ++   +EKQ++    +  + ++  +EE  +++         E+
Sbjct: 504  EALKQDQWKIK--IIQAKSSVLEEKQQMESQKKDIEEKLRLIEEEKEVIYRQNQNYQNEN 561

Query: 272  SKLAQELEQXXXXXXXXXXXXXXLAK--QSIEPSCEEKTEIEEKGSL---EIANMTELTK 326
            ++L    +               L K  Q  E   +   E+E++      ++  + EL K
Sbjct: 562  TQLKNCYKTVEKQFKDAVKENDKLKKKQQEFEEKQKRLEELEQQSQQLQEQLQELEELRK 621

Query: 327  KIELLEHLNCQIRQTNKELENKLATMGT-ESKAVSSPSK-----KGSPLISRKSGRNTAS 380
            + E ++      +++  E+E +L+++   +S   S+ +      K   L  ++       
Sbjct: 622  QNEDIQQQLISEKKSRLEIETQLSSLRQLDSNNPSAQNSFIEEDKEQLLAEKEKLEEDLK 681

Query: 381  KMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISE-KDTXXXXXX 439
            +     S++  +  +  T+    + +  K+E   + L K + +KE +  E ++       
Sbjct: 682  EALRTKSEIELQKASFQTENASFRQQYKKIE---KQLKKSIKEKEALKKELENEKKLFAE 738

Query: 440  XXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVK 499
                G+  +I QL+ E +Q  E        ++  + N++  +Q++   E  +   D   K
Sbjct: 739  QLQSGEAKVIEQLKQELKQTKEERDEFQKRSSKLE-NKLKSLQQEQNMEKMETDFD---K 794

Query: 500  DLIEKLKSAEEQITQLNDEIDAANKNMIK-VKSNHKLKLKQMQKTIDNFSKVSDSNKEIV 558
             + EK+ +A+ Q+ +    ++A  +++ K ++  ++ KL   +K+    S+  +  + + 
Sbjct: 795  QIEEKINAAKSQVIEEKQVLEAEKEDIQKKLEETNREKLLIERKSQAVLSENQNFQQTLS 854

Query: 559  RLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYK-KMIEMENLAETRLKAIS 617
             L +EL    ++   ++ E  +L+          +IE    K    E E+  E   +   
Sbjct: 855  SLQKELKVAIKERDSIKNEVTSLRNKFAK--KVELIEKLKTKFGYQEEEDQEEEEQEDPK 912

Query: 618  LLESQKFDLVQELHILQQKYDEVEDKLADISQLQS--DQVCSEIKSVHLEEQIDALSASK 675
            L+     ++   L  + Q  +E ED +  I + QS  D++ S+     LEE+ D  +++K
Sbjct: 913  LMHQHNREVRDLLTQIDQLKEEKEDLIQQIKEKQSKIDELQSDSSMQKLEEEYDEENSNK 972

Query: 676  KELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISEL 735
             EL + I+NL   K ++       ++  +++  + +  +++N +L  KL + + +KIS+L
Sbjct: 973  TELQVQIDNLVKQKSRVEIENNYYKDTYKNVEKEFKKSVKQNDELKKKLAE-AEQKISQL 1031

Query: 736  LAKINHEEQSK--IQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRY 793
              K+  E+Q +   + Q  I++  Q     I  ++ +L K K+    L+  +  + D   
Sbjct: 1032 EKKVPKEDQEEGDEEEQQQIESSAQAE---INELKQQLEKVKNENKNLKNELNSITDSNK 1088

Query: 794  SLERKADQLGSYLQEKQKAYSEYTIQ--EDELVNRLAVLMDHDRVVEKQLLEIEHENKE- 850
             L+ KA +     Q+ ++  +EY  Q  ED+L    ++ +    V+E +  EI ++  + 
Sbjct: 1089 DLQ-KAIEDAREEQQIKRLENEYDNQPDEDKLEKAKSMFIQEKLVLEIEKEEIANQLSQK 1147

Query: 851  ------LQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLA----ESESTK----- 895
                  LQK +Q ++ EN  L+ +    ++ +   V++ +    +    E+E+ K     
Sbjct: 1148 LSELDSLQKSSQQIVLENNGLKSTFKSFEKEFKRTVKENDELKKSFKKMETENQKIKDQV 1207

Query: 896  --YQTQL-------RDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVL 946
              Y+ QL        D E +   + ++HQ  + Q     ++   E   +    +++ +  
Sbjct: 1208 AMYKQQLGIVDTPTEDQEEDQSPVQNKHQQPLKQSNHSDQEFN-ELQDKYNLMVKEFEEF 1266

Query: 947  NEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDK---HVQKQQTQSPDY 1003
             +++E  I    + E  LQ+ K  IE +     +L +    L  +   H Q   T    +
Sbjct: 1267 KKEHEMQIMEFQEKEVYLQKTKTEIEQIEWEKSDLERKANSLSQEQSTHKQFYVTLEKQF 1326

Query: 1004 TEQY--INEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKL------AQFTT 1055
             +    I+ + K N  L +  E +  L  ++   Q        D E KL       + T 
Sbjct: 1327 KKSVKEIDNLRKDNDKLVKYKERLSELVSQVIKKQEPLDEQNGDEEDKLLTVNPLVELTR 1386

Query: 1056 KLENMEEEMQRVSKQLLD-SKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMII 1114
            +   +E++   +++QL + SKQ+N+     V++ +D   E+ E  LT ++   + E   +
Sbjct: 1387 QKAMLEQKNSYLTEQLEEMSKQNNQPSPAYVQQNNDNGAEVSE--LTEQLQNEQNENKSL 1444

Query: 1115 SSTIEPMSDDANNVDXXXXXXXXXXXX------LKVQEEEEFIQERSV-LQEQSAKL--- 1164
             + I  + D     D                  LK+QE+++ + E+   L E   +L   
Sbjct: 1445 KAQIRTIEDQYQQKDSEQKDKIAELETQLQEIKLKLQEKDQKVNEKEKKLNELLGQLDQQ 1504

Query: 1165 NTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSI 1224
            N E+++ YT I Q +  N EL      NQE I +L+ +++ L  +N  ++    +    +
Sbjct: 1505 NQEIKKQYTFIQQSQQNNKELAKK---NQE-IEELQLQVKDLILDN-KIVEQYKQQNEML 1559

Query: 1225 SSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETN 1284
             +  +     + E+ ++   Q     +  E ++ V+L+  +    QL    +   ++  +
Sbjct: 1560 KNKCEILESSLTEI-QEKKNQLINKIKDKESKIEVELNQIKQVNHQLAQQNEMLKKDRIS 1618

Query: 1285 KIVTMEQVTSLQNKLQDKEEH 1305
             +V +EQ   LQN   D  +H
Sbjct: 1619 MLVELEQAIQLQN--VDNRQH 1637



 Score =  108 bits (259), Expect = 1e-21
 Identities = 272/1287 (21%), Positives = 539/1287 (41%), Gaps = 175/1287 (13%)

Query: 140  QLGDVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXX 199
            Q  D    ++ +K+K       Q +++ +E     LQE++ E ++ +  +N+        
Sbjct: 574  QFKDAVKENDKLKKKQQEFEEKQKRLEELEQQSQQLQEQLQELEE-LRKQNEDIQQQLIS 632

Query: 200  XXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKL 259
                           +Q  +    N  A  +  +++K++LL + E  +  +         
Sbjct: 633  EKKSRLEIETQLSSLRQLDS---NNPSAQNSFIEEDKEQLLAEKEKLEEDLKEALRTKSE 689

Query: 260  LEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIA 319
            +E  +     E++   Q+ ++              L K   E   E+K   E+  S E  
Sbjct: 690  IELQKASFQTENASFRQQYKKIEKQLKKSIKEKEALKK---ELENEKKLFAEQLQSGEAK 746

Query: 320  NMTELTKKIELLEHLNCQIRQTNKELENKLATMGTE---SKAVSSPSKKGSPLISRKSGR 376
             + +L ++++  +    + ++ + +LENKL ++  E    K  +   K+    I+    +
Sbjct: 747  VIEQLKQELKQTKEERDEFQKRSSKLENKLKSLQQEQNMEKMETDFDKQIEEKINAAKSQ 806

Query: 377  NTASK---------MKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYV 427
                K         ++    + + E L  +   +   +E    +  + SL K+L   +  
Sbjct: 807  VIEEKQVLEAEKEDIQKKLEETNREKLLIERKSQAVLSENQNFQQTLSSLQKEL---KVA 863

Query: 428  ISEKDT---XXXXXXXXXXGKDTLIAQLQL---------EHQQHMEGPSLIHVGTNTEDV 475
            I E+D+              K  LI +L+          + ++  E P L+H   +  +V
Sbjct: 864  IKERDSIKNEVTSLRNKFAKKVELIEKLKTKFGYQEEEDQEEEEQEDPKLMH--QHNREV 921

Query: 476  NEIAKVQEQLKQELNDEIKDVNVK-DLIEKLKSAEEQITQLNDEIDA--ANKNMIKVKSN 532
             ++    +QLK+E  D I+ +  K   I++L+S +  + +L +E D   +NK  ++V+ +
Sbjct: 922  RDLLTQIDQLKEEKEDLIQQIKEKQSKIDELQS-DSSMQKLEEEYDEENSNKTELQVQID 980

Query: 533  HKLKLKQMQKTIDNFSKVSDSN--KEIVRLTEELHHLSQKVAELEEEKGNLQLHLV---- 586
            + +K K   +  +N+ K +  N  KE  +  ++   L +K+AE E++   L+  +     
Sbjct: 981  NLVKQKSRVEIENNYYKDTYKNVEKEFKKSVKQNDELKKKLAEAEQKISQLEKKVPKEDQ 1040

Query: 587  ---DYDSGRMIESDVYKKMIEMENLAE--------TRLKAISLLESQKFDL--------- 626
               D +  + IES    ++ E++   E         + +  S+ +S K DL         
Sbjct: 1041 EEGDEEEQQQIESSAQAEINELKQQLEKVKNENKNLKNELNSITDSNK-DLQKAIEDARE 1099

Query: 627  VQELHILQQKYDEV--EDKLADI-SQLQSDQVCSEIKSVHLEEQ-------IDALSASKK 676
             Q++  L+ +YD    EDKL    S    +++  EI+   +  Q       +D+L  S +
Sbjct: 1100 EQQIKRLENEYDNQPDEDKLEKAKSMFIQEKLVLEIEKEEIANQLSQKLSELDSLQKSSQ 1159

Query: 677  ELALVIENLK-----LDKE---------QLYGTIKDLENDKEDIMNKLQNYIQE----NM 718
            ++ L    LK      +KE         +L  + K +E + + I +++  Y Q+    + 
Sbjct: 1160 QIVLENNGLKSTFKSFEKEFKRTVKENDELKKSFKKMETENQKIKDQVAMYKQQLGIVDT 1219

Query: 719  DLTDKLEKMS--AEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKS 776
               D+ E  S    K  + L + NH +Q   + Q   +  ++E + + +  E ++ +++ 
Sbjct: 1220 PTEDQEEDQSPVQNKHQQPLKQSNHSDQEFNELQDKYNLMVKEFEEFKKEHEMQIMEFQE 1279

Query: 777  RICRLEES---IAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVL-MD 832
            +   L+++   I  +E  +  LERKA+ L       ++ Y     Q  + V  +  L  D
Sbjct: 1280 KEVYLQKTKTEIEQIEWEKSDLERKANSLSQEQSTHKQFYVTLEKQFKKSVKEIDNLRKD 1339

Query: 833  HDRVV--EKQLLEI----------------EHENK--------ELQKKNQILLEENQNLQ 866
            +D++V  +++L E+                + E+K        EL ++  +L ++N  L 
Sbjct: 1340 NDKLVKYKERLSELVSQVIKKQEPLDEQNGDEEDKLLTVNPLVELTRQKAMLEQKNSYLT 1399

Query: 867  ISLSDMQQHYN----ALVEKANRTDLAESESTKY----QTQLRDLESNLKRITHEHQTLI 918
              L +M +  N    A V++ N      SE T+     Q + + L++ ++ I  ++Q   
Sbjct: 1400 EQLEEMSKQNNQPSPAYVQQNNDNGAEVSELTEQLQNEQNENKSLKAQIRTIEDQYQQKD 1459

Query: 919  VQKKKEIEDLEIEF-NTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNN---IENL 974
             ++K +I +LE +    +++   +D+KV NEK +K  E + QL+ Q QE K     I+  
Sbjct: 1460 SEQKDKIAELETQLQEIKLKLQEKDQKV-NEKEKKLNELLGQLDQQNQEIKKQYTFIQQS 1518

Query: 975  NMNVEELNKMNLELIDKHVQ-KQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKIN 1033
              N +EL K N E+ +  +Q K         EQY     + N +LK K E + +   +I 
Sbjct: 1519 QQNNKELAKKNQEIEELQLQVKDLILDNKIVEQY----KQQNEMLKNKCEILESSLTEIQ 1574

Query: 1034 NAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIK 1093
              +   ++ + D ES       K+E    ++++V+ QL    +  ++ +I +  + +Q  
Sbjct: 1575 EKKNQLINKIKDKES-------KIEVELNQIKQVNHQLAQQNEMLKKDRISMLVELEQAI 1627

Query: 1094 ELKETKLTFEMNIPKTEGMIIS--STIEPMS-DDANNVDXXXXXXXXXXXXLKVQEEEEF 1150
            +L+        NIP +     S  +   P S  D  N +             KV  EE +
Sbjct: 1628 QLQNVDNRQHFNIPTSGSKFTSPNNLKNPKSLTDIQNDNQAKIQDKIHEYQQKVY-EEVY 1686

Query: 1151 IQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQ-EQINQLKSK--LE-QL 1206
             Q+   L E +  L +E  + Y K  +L  L  E   HD +   +QI + K    L+ +L
Sbjct: 1687 NQQDDDLNE-NYPLPSEGSDGYGK--KLSKLEDEF--HDQIQALKQIIKSKEHEILQLKL 1741

Query: 1207 NTENDNLLSTVAELRSSISSAVDQR--GFEIAELWKQHLAQREADFQKTEHELRVQLSAF 1264
            N E +NL  T  + +  IS    QR  GF+IA    Q +     D +   H   +     
Sbjct: 1742 NKEENNLEITPRD-KKVISDISPQRKTGFKIATGSNQQITDYATDRRTKNHSANM----- 1795

Query: 1265 ESKYEQLLDSVQSSTQEETNKIVTMEQ 1291
               Y Q + S+Q++  +  +K++   Q
Sbjct: 1796 --LYYQSIQSIQNNQGDSQSKLLGSTQ 1820



 Score = 87.8 bits (208), Expect = 2e-15
 Identities = 153/806 (18%), Positives = 350/806 (43%), Gaps = 66/806 (8%)

Query: 806  LQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNL 865
            L+EKQ    + TI++D   +        D ++  + L+ + +   L+++ + L EEN   
Sbjct: 263  LKEKQFETLKQTIEQDNKSDGSR----SDEILSSKSLDDDEKKYNLEEQIEQLKEENMFK 318

Query: 866  QISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEI 925
            QI + ++     AL +K +  D        YQ    D    L +I   +Q L      E 
Sbjct: 319  QIKIDNLLVQLGALEQKQSSFD--------YQDAKID---ELMQIIRTNQEL-----SEQ 362

Query: 926  EDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMN 985
             D    FNT +   I D+KV+ +K  K  +    L  +  E KN+++  N    +L K  
Sbjct: 363  FDNNSNFNTDLNERILDRKVILQKQNKLEKKNKSLRVENIELKNSLKVFNNETSKLEK-K 421

Query: 986  LELIDKHVQ-KQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVS 1044
            LE+  K+ +      + +++E+ +  I +LN +++ + +EI  L   I   Q+   +   
Sbjct: 422  LEVEKKNNKLLNDILNQEFSEKQL--IAQLNDIIENQKQEISELKIDIEQLQIKVDNSKQ 479

Query: 1045 DYE----SKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQ--DDQIKELKE- 1097
            ++E    +  +Q   ++EN  ++ + + +     K    +  +L  +Q  + Q K+++E 
Sbjct: 480  EFEYIKSNPNSQDFDEMENEYDQAEALKQDQWKIKIIQAKSSVLEEKQQMESQKKDIEEK 539

Query: 1098 -TKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSV 1156
               +  E  +   +     +    + +    V+            LK ++++EF +++  
Sbjct: 540  LRLIEEEKEVIYRQNQNYQNENTQLKNCYKTVEKQFKDAVKENDKLK-KKQQEFEEKQKR 598

Query: 1157 LQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLST 1216
            L+E    L  + Q+   ++ +LE L  +   ++ + Q+ I++ KS+LE + T+  +L   
Sbjct: 599  LEE----LEQQSQQLQEQLQELEELRKQ---NEDIQQQLISEKKSRLE-IETQLSSLRQL 650

Query: 1217 VAELRSSISSAVDQRGFE-IAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSV 1275
             +   S+ +S +++   + +AE  K+ L +   +  +T+ E+ +Q ++F+++        
Sbjct: 651  DSNNPSAQNSFIEEDKEQLLAE--KEKLEEDLKEALRTKSEIELQKASFQTENASFRQQY 708

Query: 1276 QSSTQEETNKIVTMEQVTSLQNKLQ-DKEEHLRNLQEKYADVINQIEILRSEIEDEKVAF 1334
            +   +++  K  ++++  +L+ +L+ +K+     LQ   A VI Q++    + ++E+  F
Sbjct: 709  K-KIEKQLKK--SIKEKEALKKELENEKKLFAEQLQSGEAKVIEQLKQELKQTKEERDEF 765

Query: 1335 XXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXR 1394
                            +   E        +Q    IN   +Q+ +              +
Sbjct: 766  QKRSSKLENKLKSLQQEQNMEKME-TDFDKQIEEKINAAKSQVIEEKQVLEAEKEDIQKK 824

Query: 1395 VNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYE 1454
            + +   + L     +E K   +  +   +  TL+    E +   ++    +  +  L  +
Sbjct: 825  LEETNREKL----LIERKSQAVLSENQNFQQTLSSLQKELKVAIKERDSIKNEVTSLRNK 880

Query: 1455 KESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKI----TESVSLNKQVAELNK 1510
               ++ ++     +     E  Q+E E E  KL+ + N ++    T+   L ++  +L +
Sbjct: 881  FAKKVELIEKLKTKFGYQEEEDQEEEEQEDPKLMHQHNREVRDLLTQIDQLKEEKEDLIQ 940

Query: 1511 ALEEEVAKTNEMQ--TALENQEIEIVTLNDEITNLQ----NMVRASSSKIQKHVSFASDT 1564
             ++E+ +K +E+Q  ++++  E E    N   T LQ    N+V+   S+++   ++  DT
Sbjct: 941  QIKEKQSKIDELQSDSSMQKLEEEYDEENSNKTELQVQIDNLVK-QKSRVEIENNYYKDT 999

Query: 1565 KQGRDEQLDNTM--NKELLDAVPRAE 1588
             +  +++   ++  N EL   +  AE
Sbjct: 1000 YKNVEKEFKKSVKQNDELKKKLAEAE 1025



 Score = 69.3 bits (162), Expect = 8e-10
 Identities = 126/677 (18%), Positives = 281/677 (41%), Gaps = 42/677 (6%)

Query: 860  EENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIV 919
            EE+ N  I   +  +   +  +  ++ +  + +  K Q Q    E  L++I +E   L++
Sbjct: 93   EESDNEDIDSKNNGKQEKSRTQNTSKYNSKKIDELKKQLQNAKNELQLQKIKYE---LMI 149

Query: 920  QKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIE-YVTQLEAQLQEYKNNIENLNMNV 978
             K  E    ++  +TQ E  I+D ++L+E++   +  Y+ Q +   + +KN    L  + 
Sbjct: 150  LKFNEFITHQVFCHTQCEQNIKDDELLSEQFNILLNTYLCQKDDYAKYFKNQSWTLQGSA 209

Query: 979  EELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVS 1038
            + L    L+  ++  Q+   Q+    +   N I K   +L+++  + I+    IN  +++
Sbjct: 210  QSLPTSPLK--NQSPQESFLQAEFLVD---NTIKKFYQILEKETSDPISYRNHIN--EIT 262

Query: 1039 YMSMVSDYESKLAQFTTKLENMEEEMQRVSKQL-LDSKQHNEELQILVREQDDQIKELKE 1097
                  +   +  +   K +    +    SK L  D K++N E QI   ++++  K++K 
Sbjct: 263  LKEKQFETLKQTIEQDNKSDGSRSDEILSSKSLDDDEKKYNLEEQIEQLKEENMFKQIKI 322

Query: 1098 TKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEE-EEFIQERSV 1156
              L  ++   + +          + +    +                  +  E I +R V
Sbjct: 323  DNLLVQLGALEQKQSSFDYQDAKIDELMQIIRTNQELSEQFDNNSNFNTDLNERILDRKV 382

Query: 1157 LQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLST 1216
            + ++  KL     E   K +++E  N EL     V   + ++L+ KLE +  +N+ LL+ 
Sbjct: 383  ILQKQNKL-----EKKNKSLRVE--NIELKNSLKVFNNETSKLEKKLE-VEKKNNKLLND 434

Query: 1217 VAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQ 1276
            +     S    + Q   +I E  KQ +++ + D +    +L++++   + ++E +  +  
Sbjct: 435  ILNQEFSEKQLIAQLN-DIIENQKQEISELKIDIE----QLQIKVDNSKQEFEYIKSNPN 489

Query: 1277 SSTQEE-TNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFX 1335
            S   +E  N+    E +   Q K++  +     L+EK      Q+E  + +IE EK+   
Sbjct: 490  SQDFDEMENEYDQAEALKQDQWKIKIIQAKSSVLEEK-----QQMESQKKDIE-EKLRLI 543

Query: 1336 XXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRV 1395
                           +  T+ ++  +  E+   +  +EN +LKK                
Sbjct: 544  EEEKEVIYRQNQNYQNENTQLKNCYKTVEKQFKDAVKENDKLKKKQQEFEEKQKRLEELE 603

Query: 1396 NDAE--AKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTY 1453
              ++   + L+   +L  ++ +I Q+      +  +   +  ++RQ              
Sbjct: 604  QQSQQLQEQLQELEELRKQNEDIQQQLISEKKSRLEIETQLSSLRQLDSNNPSAQNSFIE 663

Query: 1454 EKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALE 1513
            E + +L   + K+ E+    E ++ +SEIE  K   +     TE+ S  +Q  ++ K L+
Sbjct: 664  EDKEQLLAEKEKLEEDLK--EALRTKSEIELQKASFQ-----TENASFRQQYKKIEKQLK 716

Query: 1514 EEVAKTNEMQTALENQE 1530
            + + +   ++  LEN++
Sbjct: 717  KSIKEKEALKKELENEK 733


>UniRef50_A0CPT0 Cluster: Chromosome undetermined scaffold_23, whole
            genome shotgun sequence; n=2; Paramecium tetraurelia|Rep:
            Chromosome undetermined scaffold_23, whole genome shotgun
            sequence - Paramecium tetraurelia
          Length = 2301

 Score =  142 bits (343), Expect = 9e-32
 Identities = 327/1612 (20%), Positives = 659/1612 (40%), Gaps = 140/1612 (8%)

Query: 90   ISESLANTLKQKEILMEKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLG------- 142
            +S ++   +KQ   + ++IKQ +E S + S  + +               ++        
Sbjct: 217  LSYNIKEIIKQNSNVQKEIKQKEEESTKQSNKLEKYKKQIEQKNSQIDSLKMDVKNLNQQ 276

Query: 143  -----DVTHLSNTIKEKDNALSVLQVKM----KIM---ETTILDLQEKINEKDQIIEAKN 190
                  +  L++ IK++   + +LQ ++    KI+   ET I   QEK N+  Q I+   
Sbjct: 277  LQNQETINSLNDCIKKQSQQIDILQQQIIEQNKILEQNETIIAKQQEKENQLFQEIKMIK 336

Query: 191  KATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRL-LKDIESKDVR 249
                                  D +Q++ ++      M  E    +Q+   ++IE K  +
Sbjct: 337  CEKVKSLQQDEDDQIKYKNTINDLRQEINELNAQLENMYTEQAQLQQQFDEQEIEHKKSQ 396

Query: 250  ISSLEEANKL-LEAARFEISLEHSKLA--QELEQXXXXXXXXXXXXXXLAKQSIEPSCEE 306
            I       K  LE  +++  +E +K+   Q+L+Q                + SI+    E
Sbjct: 397  IQMTNTIQKFQLEVKKYQQLVEDNKIQFNQQLKQQQQQHKQIQQELIN-NQNSIQNQLSE 455

Query: 307  KTEIEEKGSLEIANMTELTKKIE-LLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKK 365
              +I E     + +   L + +E L+++LN  I+Q  K L+N  +T    S  +   SK 
Sbjct: 456  YLQIIE----NLKSKENLNQVLENLIDNLNLVIKQ--KLLQNLKSTSSLASSPMRGMSKN 509

Query: 366  GSPL--ISRKSGRN--TASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDL 421
             SP+  I   +  N     K+ S    +S + LN+  +  I K+E  K + +IQ   + +
Sbjct: 510  SSPVRQILNHNNNNQIDLQKIHSTLDNISEQFLNR-LNLLIKKDE--KNQELIQHYCQQI 566

Query: 422  VDKEYVISE--KDTXXXXXXXXXXGKDTLIAQL-QLEHQQHM--EGPSLIH-VGTNTEDV 475
             + +  I +   D            K   I ++  L+ ++    E  S I  +  N   +
Sbjct: 567  EESQQTIQQLCDDNDQQKQFITQMCKILNIEKIDDLKERKSFSKEDQSYIETLNQNNAQI 626

Query: 476  NEIAKVQEQLKQELNDE---IKDVNV-----KDLIEKLKSAEEQ----ITQLNDEIDAAN 523
             ++    ++L+Q++  +   IKD  +     K+ I+ L   +E      TQ+     ++ 
Sbjct: 627  QQLISYNQELQQDIQQQQIIIKDYEIQIDHLKNQIKYLSQEKEDQCKFTTQIASPTQSSR 686

Query: 524  K-NMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQ 582
            K ++IK+  N +++ +  Q +  N  K+S  + EI  L  +L    + V    EE  +L 
Sbjct: 687  KDSIIKILQNEEIQNRDQQISELN-DKISILDIEISNLQHQLESQIKLVQSRNEEIQHLN 745

Query: 583  LHLVDYDSGRMIESDVYKKMIEMENLAETRLKA-ISLLESQKFDLVQELHILQQKYDEVE 641
              + D    +     +  ++      ++ + +  I  LE   +D+               
Sbjct: 746  SQVRDLLEKQQYFEQLINELNAYHQQSKNQQEVQIIKLEGVSYDISHNSFNFDALRTPTN 805

Query: 642  DK--LADISQLQS-DQVCSEIKSVHLEEQI-DALSASKKELALVIENLKLDKEQLYGTIK 697
                + +I Q QS +   S I  +    QI   +  +K++   +I+  +L +E+     K
Sbjct: 806  QNYIIDEIQQEQSINSSLSSIVQMSPNTQIKQIIQLNKQQEENIIQKNRLIQEKEVDLEK 865

Query: 698  DLE--NDKEDIMNKLQNYIQE-NMDLTDKLEKMSAEKISELLAKINHEEQSK---IQTQF 751
              E     + I  K +  I E N+ LT   EK+   +  +   +  ++E +K   I+ Q 
Sbjct: 866  QNEELQQLQSINAKNEQEINELNLQLTQLHEKIETLREEQTQIQQQNDEYTKKLVIEKQS 925

Query: 752  GIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSL---ERKADQLGSYLQE 808
             ID +I+     I+ ++S   +  ++I  L   +   ++ + +L   E+   Q    +Q 
Sbjct: 926  AID-QIELYKKEIQQVKSINDQLSTQIAELRIQLQTNQEEQITLTENEQIIQQQNKEIQF 984

Query: 809  KQKAYSEYTI---QEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNL 865
             +   +E  I   Q+D  +  L    DH +   K L  I   N  +++   I  EE Q +
Sbjct: 985  LKTINNEKQIQISQQDYQLQNLKEQFDHLKSKSKNL--IIKTNSAIKEIKIIHAEELQQI 1042

Query: 866  QISLSDMQQ--HYNALVEKANRTDLAESESTK-YQTQLRDLESNLKRIT-HEHQTLIVQK 921
            +++L   QQ   Y+    +     + +S  +K Y  Q++ LES    +   E   L+ Q 
Sbjct: 1043 KVNLLQEQQLLKYDMKQLETKFVAIEQSYQSKIYNAQVKILESEQSIVQFQEELKLLQQS 1102

Query: 922  KKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEEL 981
            K +IE+   +   +     +     N K +     + Q E QLQ  +  I+  + ++E+ 
Sbjct: 1103 KLQIEEKYCKAQDEFLEQSQFIDQQNTKLKSQKSQLEQKEKQLQCIEIQIQEQSDHIEQS 1162

Query: 982  NKMNLELIDKHVQKQQTQSPDYTEQ-YINEINKLNA----LLKQKDEEIIALNQKINNAQ 1036
            N+    L  +  Q QQ  S    E+  I+++N+ N+    LL+QK++++  L+ ++ N Q
Sbjct: 1163 NQTTKTLQLEINQLQQILSQQLQEKNLIHDLNQQNSEKQQLLQQKEQQLKVLHSELENLQ 1222

Query: 1037 VSYMSMVSDYESKLAQFTTK-------LENMEEEMQRVSKQLLDSKQHNEELQILVREQD 1089
            +    +V +   K      K       LE  E  ++ V++ L  +KQ  +    L+ + +
Sbjct: 1223 LQLDGIVQNQREKEQNLNVKILDQQSQLEQYESRLKEVTQTLQHNKQEFQNRINLIEQVN 1282

Query: 1090 DQIKELKETKLT----FEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQ 1145
              + E  +  +      E+N       I+    E       + +             K+Q
Sbjct: 1283 QDLNEKNQNNIVQIQKLEINEELMNKKILELEFELAKIRNESQEKARELSLINQDYHKLQ 1342

Query: 1146 EE-EEFIQERSVLQEQSAKLNTEL----QECYTKIIQLETLNTELTGHDVVNQEQINQLK 1200
            ++ ++ IQ+   L +Q+ K   ++    Q   TK  QL  LN +L      NQ+  +Q  
Sbjct: 1343 DDLKKEIQKAQNLIDQNIKYEQDIIQLKQNLTTKDQQLVGLNEQLNVSIKQNQDIQSQYT 1402

Query: 1201 SKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEI-AELWKQHLAQREADFQKTE----H 1255
             K+ QL  +  NL      L  S    + ++   +  +L KQ+L + + +   ++     
Sbjct: 1403 LKVTQLEKQIINLEREKLLLNESNDQLIREKQNNLQQQLTKQNLNEEKENATSSQEVKIQ 1462

Query: 1256 ELRVQLSAFESKYEQLLDSVQSSTQEETN-KIVTMEQVTS--------LQNKLQDKEEHL 1306
            +L+ QL   +   +QL DS Q   Q+  N K   ++Q+TS        L    Q   EHL
Sbjct: 1463 QLKDQLQKEQENIKQLQDSHQKQIQQYFNEKSQQIQQLTSNNDNLTLQLNESKQISNEHL 1522

Query: 1307 RNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQS 1366
             N  +K   +IN       + E   + +                 L      +  + EQ+
Sbjct: 1523 -NDNDKLKSIINNQLTQIKQFEQAIIQYKNQLQDVKSQNENLVTILHQSENKWTNLNEQN 1581

Query: 1367 I---LNINEENAQLKKSSXXXXXXXXXXXXRV---NDAEAKVLELTHQL--ELKDSEIYQ 1418
                L+I ++  Q+++ S            ++    D E K+ E+ +QL  E + SE   
Sbjct: 1582 TQYKLSIQQQEHQIQQQSLLILTQEEALKKQIIINVDQEKKLFEINNQLWQEQQVSEDLN 1641

Query: 1419 KTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKE---SELAILRLKMHENANHYET 1475
               +  +  +QR+++   + QQ+ + + ++ +   E +   SE   LR    EN N  ++
Sbjct: 1642 LNKQKKLEQSQRDNDL--LLQQVKQLQDKLNECQNELQVLKSENNQLRELSEENINQTQS 1699

Query: 1476 MQK--ESEIERV-KLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIE 1532
            ++   ++++ ++ +L  +L+    +  S  K++ EL   L+  +A+  E Q   +   + 
Sbjct: 1700 IKALYQNQLFQISELRNDLSESEEKEGSNLKRIEELTNQLQNVLAE-KEKQRLNQEAGVN 1758

Query: 1533 IVTLNDEITNLQ--NMVRASSSKIQKHVSFASDTKQGRDE---QLDNTMNKE 1579
             +    ++  +Q   + +    +I+++    +   Q ++E   QL++ + K+
Sbjct: 1759 GILKEKQLIEIQLNEVTQTGLKQIEQYKQEIAQLNQEKEEIKKQLEDNLEKK 1810



 Score =  138 bits (333), Expect = 2e-30
 Identities = 266/1318 (20%), Positives = 573/1318 (43%), Gaps = 142/1318 (10%)

Query: 317  EIANMTELTKKIEL-LEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGS--PLISRK 373
            +I     + K  E+ ++HL  QI+  ++E E++     T+  + +  S+K S   ++  +
Sbjct: 639  DIQQQQIIIKDYEIQIDHLKNQIKYLSQEKEDQ-CKFTTQIASPTQSSRKDSIIKILQNE 697

Query: 374  SGRNT---ASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLN---KDLVDK--- 424
              +N     S++    S L  E  N     +     +      IQ LN   +DL++K   
Sbjct: 698  EIQNRDQQISELNDKISILDIEISNLQHQLESQIKLVQSRNEEIQHLNSQVRDLLEKQQY 757

Query: 425  -EYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQE 483
             E +I+E +            +   +  +  +   +      +   TN   + +  + ++
Sbjct: 758  FEQLINELNAYHQQSKNQQEVQIIKLEGVSYDISHNSFNFDALRTPTNQNYIIDEIQQEQ 817

Query: 484  QLKQELNDEIK---DVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQM 540
             +   L+  ++   +  +K +I+  K  EE I Q N  I    K +   K N +L+  Q+
Sbjct: 818  SINSSLSSIVQMSPNTQIKQIIQLNKQQEENIIQKNRLIQ--EKEVDLEKQNEELQ--QL 873

Query: 541  QK-TIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVY 599
            Q     N  ++++ N ++ +L E++  L ++  +++++       LV      + + ++Y
Sbjct: 874  QSINAKNEQEINELNLQLTQLHEKIETLREEQTQIQQQNDEYTKKLVIEKQSAIDQIELY 933

Query: 600  KKMIEM---------ENLAETRLKAISLLESQKFDLVQELHILQQKYDEVE--DKLADIS 648
            KK I+            +AE R++ +   + ++  L +   I+QQ+  E++    + +  
Sbjct: 934  KKEIQQVKSINDQLSTQIAELRIQ-LQTNQEEQITLTENEQIIQQQNKEIQFLKTINNEK 992

Query: 649  QLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMN 708
            Q+Q  Q   ++++  L+EQ D L +  K L  +I+     KE      ++L+  K +++ 
Sbjct: 993  QIQISQQDYQLQN--LKEQFDHLKSKSKNL--IIKTNSAIKEIKIIHAEELQQIKVNLLQ 1048

Query: 709  KLQNYIQENMDLTDK---LEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIE 765
            + Q    +   L  K   +E+    KI     KI   EQS +Q Q  +   +Q+  L IE
Sbjct: 1049 EQQLLKYDMKQLETKFVAIEQSYQSKIYNAQVKILESEQSIVQFQEELKL-LQQSKLQIE 1107

Query: 766  NIESELS-KYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELV 824
                +   ++  +   +++    ++ ++  LE+K  QL   ++ + +  S++  Q ++  
Sbjct: 1108 EKYCKAQDEFLEQSQFIDQQNTKLKSQKSQLEQKEKQL-QCIEIQIQEQSDHIEQSNQTT 1166

Query: 825  NRLAVLMDH-DRVVEKQLLE---IEHENKELQKKNQILLEENQNLQI---SLSDMQQHYN 877
              L + ++   +++ +QL E   I   N++  +K Q+L ++ Q L++    L ++Q   +
Sbjct: 1167 KTLQLEINQLQQILSQQLQEKNLIHDLNQQNSEKQQLLQQKEQQLKVLHSELENLQLQLD 1226

Query: 878  ALVEKANRTDLAESESTKY---QTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNT 934
             +V+  N+ +  ++ + K    Q+QL   ES LK +T   QTL  Q  K+      EF  
Sbjct: 1227 GIVQ--NQREKEQNLNVKILDQQSQLEQYESRLKEVT---QTL--QHNKQ------EFQN 1273

Query: 935  QIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQ 994
            +I    +  + LNEK + NI  + +LE              +N E +NK  LEL +  + 
Sbjct: 1274 RINLIEQVNQDLNEKNQNNIVQIQKLE--------------INEELMNKKILEL-EFELA 1318

Query: 995  KQQTQSPDYTEQ--YIN-EINKLNALLK---QKDEEIIALNQKINNAQVSYMSMVSDYES 1048
            K + +S +   +   IN + +KL   LK   QK + +I  N K     +     ++  + 
Sbjct: 1319 KIRNESQEKARELSLINQDYHKLQDDLKKEIQKAQNLIDQNIKYEQDIIQLKQNLTTKDQ 1378

Query: 1049 KLAQFTTKL-----ENMEEEMQRVSKQLLDSKQ--HNEELQILVREQDDQIKELKETKLT 1101
            +L     +L     +N + + Q   K     KQ  + E  ++L+ E +DQ+   K+  L 
Sbjct: 1379 QLVGLNEQLNVSIKQNQDIQSQYTLKVTQLEKQIINLEREKLLLNESNDQLIREKQNNLQ 1438

Query: 1102 FEM---NIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQ 1158
             ++   N+ + +    SS    +    + +              + Q ++ F ++   +Q
Sbjct: 1439 QQLTKQNLNEEKENATSSQEVKIQQLKDQLQKEQENIKQLQDSHQKQIQQYFNEKSQQIQ 1498

Query: 1159 E-QSAKLNTELQECYTKIIQLETLNTELTGHDVVN---------QEQINQLKSKLEQLNT 1208
            +  S   N  LQ   +K I  E LN       ++N         ++ I Q K++L+ + +
Sbjct: 1499 QLTSNNDNLTLQLNESKQISNEHLNDNDKLKSIINNQLTQIKQFEQAIIQYKNQLQDVKS 1558

Query: 1209 ENDNLLSTVAELRSSISSAVDQR-GFEIAELWKQHLAQREADFQKTEHE-LRVQLSAFES 1266
            +N+NL++ + +  +  ++  +Q   ++++   ++H  Q+++    T+ E L+ Q+     
Sbjct: 1559 QNENLVTILHQSENKWTNLNEQNTQYKLSIQQQEHQIQQQSLLILTQEEALKKQIIINVD 1618

Query: 1267 KYEQLLD-SVQSSTQEETNKIVTMEQVTSLQNKLQDKE---EHLRNLQEKYADVINQIEI 1322
            + ++L + + Q   +++ ++ + + +   L+   +D +   + ++ LQ+K  +  N++++
Sbjct: 1619 QEKKLFEINNQLWQEQQVSEDLNLNKQKKLEQSQRDNDLLLQQVKQLQDKLNECQNELQV 1678

Query: 1323 LRS------EIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQ 1376
            L+S      E+ +E +                  +LR +    ++ +  ++  I E   Q
Sbjct: 1679 LKSENNQLRELSEENINQTQSIKALYQNQLFQISELRNDLSESEEKEGSNLKRIEELTNQ 1738

Query: 1377 LKKSSXXXXXXXXXXXXRVND-------AEAKVLELTH----QLELKDSEIYQKTHEYTI 1425
            L+                VN         E ++ E+T     Q+E    EI Q   E   
Sbjct: 1739 LQNVLAEKEKQRLNQEAGVNGILKEKQLIEIQLNEVTQTGLKQIEQYKQEIAQLNQEKEE 1798

Query: 1426 TLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKE--SEIE 1483
               Q  D  E  +Q   E  +++ ++  E + E+  L+ K +EN    E  Q +   +++
Sbjct: 1799 IKKQLEDNLEKKKQVEEELNQKVNNIRLEFQLEIDQLKQKQYENQKAIEDQQNQLIIQVQ 1858

Query: 1484 RVK-----LIEELNV---KITESVSLNKQVAELNKALEEEVAKTN-EMQTALENQEIE 1532
            + K     LI E+N         +S N+Q+   NK L++ ++++N +     + Q+IE
Sbjct: 1859 QEKQQQNSLIAEINKIQNDFNNEMSKNQQLMHENKRLQKFLSQSNLDKDLMHDRQQIE 1916



 Score =  136 bits (328), Expect = 6e-30
 Identities = 275/1351 (20%), Positives = 573/1351 (42%), Gaps = 118/1351 (8%)

Query: 321  MTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTAS 380
            +T+L +KIE L     QI+Q N E   KL              +K S +   +  +    
Sbjct: 891  LTQLHEKIETLREEQTQIQQQNDEYTKKLVI------------EKQSAIDQIELYKKEIQ 938

Query: 381  KMKSPWSQLSSETLNQDTDKKINKNE---IAKLEMVIQSLNKDLV-------DKEYVISE 430
            ++KS   QLS++        + N+ E   + + E +IQ  NK++        +K+  IS+
Sbjct: 939  QVKSINDQLSTQIAELRIQLQTNQEEQITLTENEQIIQQQNKEIQFLKTINNEKQIQISQ 998

Query: 431  KDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELN 490
            +D              +    L ++    ++   +IH     +    + + Q+ LK ++ 
Sbjct: 999  QDYQLQNLKEQFDHLKSKSKNLIIKTNSAIKEIKIIHAEELQQIKVNLLQEQQLLKYDMK 1058

Query: 491  D-EIKDVNVKDLIE-KLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQ-KTIDNF 547
              E K V ++   + K+ +A+ +I +    I    + + K+    KL++++   K  D F
Sbjct: 1059 QLETKFVAIEQSYQSKIYNAQVKILESEQSIVQFQEEL-KLLQQSKLQIEEKYCKAQDEF 1117

Query: 548  SKVSDS-NKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEME 606
             + S   +++  +L  +   L QK  +L+  +  +Q      +        +  ++ +++
Sbjct: 1118 LEQSQFIDQQNTKLKSQKSQLEQKEKQLQCIEIQIQEQSDHIEQSNQTTKTLQLEINQLQ 1177

Query: 607  NLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADIS--QLQSDQVCSEIK---- 660
             +   +L+  +L+        ++  +LQQK  +++   +++   QLQ D +    +    
Sbjct: 1178 QILSQQLQEKNLIHDLNQQNSEKQQLLQQKEQQLKVLHSELENLQLQLDGIVQNQREKEQ 1237

Query: 661  --SVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENM 718
              +V + +Q   L   +  L  V + L+ +K++    I  +E   +D+  K QN I +  
Sbjct: 1238 NLNVKILDQQSQLEQYESRLKEVTQTLQHNKQEFQNRINLIEQVNQDLNEKNQNNIVQIQ 1297

Query: 719  DLTDKLEKMSAEKISEL---LAKINHEEQSKIQTQFGIDA---KIQERDLYIE-----NI 767
             L    E M+ +KI EL   LAKI +E Q K +    I+    K+Q+ DL  E     N+
Sbjct: 1298 KLEINEELMN-KKILELEFELAKIRNESQEKARELSLINQDYHKLQD-DLKKEIQKAQNL 1355

Query: 768  ESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRL 827
              +  KY+  I +L++++   + +   L    +QL   +++ Q   S+YT++  +L  ++
Sbjct: 1356 IDQNIKYEQDIIQLKQNLTTKDQQLVGLN---EQLNVSIKQNQDIQSQYTLKVTQLEKQI 1412

Query: 828  AVLMDHDRVVEK---QLLEIEHENKELQKKNQILLEENQNLQISLS-DMQQHYNALV-EK 882
              L     ++ +   QL+  +  N + Q   Q L EE +N   S    +QQ  + L  E+
Sbjct: 1413 INLEREKLLLNESNDQLIREKQNNLQQQLTKQNLNEEKENATSSQEVKIQQLKDQLQKEQ 1472

Query: 883  ANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQ--KKKEIEDLEIEFNTQIESAI 940
             N   L +S   + Q    +    ++++T  +  L +Q  + K+I +  +  N +++S I
Sbjct: 1473 ENIKQLQDSHQKQIQQYFNEKSQQIQQLTSNNDNLTLQLNESKQISNEHLNDNDKLKSII 1532

Query: 941  RDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQ---Q 997
             ++    +++E+ I    Q + QLQ+ K+  ENL   + +       L +++ Q +   Q
Sbjct: 1533 NNQLTQIKQFEQAI---IQYKNQLQDVKSQNENLVTILHQSENKWTNLNEQNTQYKLSIQ 1589

Query: 998  TQSPDYTEQYINEINKLNALLKQ------KDEEIIALNQKINNAQVSYMSMVSDYESKLA 1051
             Q     +Q +  + +  AL KQ      +++++  +N ++   Q     +  + + KL 
Sbjct: 1590 QQEHQIQQQSLLILTQEEALKKQIIINVDQEKKLFEINNQLWQEQQVSEDLNLNKQKKLE 1649

Query: 1052 QFTTKLENMEEEMQRVSKQLLDS-KQHNEELQILVREQDDQIKELKETKLTFEMNIPKTE 1110
            Q  ++ +N +  +Q+V KQL D   +   ELQ+L + +++Q++EL E  +    +I    
Sbjct: 1650 Q--SQRDN-DLLLQQV-KQLQDKLNECQNELQVL-KSENNQLRELSEENINQTQSIKALY 1704

Query: 1111 GMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQE 1170
               +   I  + +D +  +            L  Q +    ++      Q A +N  L+E
Sbjct: 1705 QNQLFQ-ISELRNDLSESEEKEGSNLKRIEELTNQLQNVLAEKEKQRLNQEAGVNGILKE 1763

Query: 1171 CYTKIIQL-ETLNTELTGHDVVNQE--QINQLKSKLE-QLNTENDNLLSTVAELRSSISS 1226
                 IQL E   T L   +   QE  Q+NQ K +++ QL    +       EL   +++
Sbjct: 1764 KQLIEIQLNEVTQTGLKQIEQYKQEIAQLNQEKEEIKKQLEDNLEKKKQVEEELNQKVNN 1823

Query: 1227 AVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKI 1286
               +   EI +L KQ   + +   +  +++L +Q+   + +   L+  +     +  N++
Sbjct: 1824 IRLEFQLEIDQL-KQKQYENQKAIEDQQNQLIIQVQQEKQQQNSLIAEINKIQNDFNNEM 1882

Query: 1287 VTMEQVTSLQNKLQ--------DKE-EHLRNLQEKYADVIN--QIEILRSE--IEDEKVA 1333
               +Q+     +LQ        DK+  H R   E+  + IN  + + LR +  I D +  
Sbjct: 1883 SKNQQLMHENKRLQKFLSQSNLDKDLMHDRQQIEQGEEKINCDENKSLRQDNSISDRQQC 1942

Query: 1334 FXXXXXXXXXXXXXXXXDLRTE-NQSYKQMQEQS-ILNINEENAQLKKSSXXXXXXXXXX 1391
                              +++  NQ+ K +  Q  I  + +EN +LK+            
Sbjct: 1943 VSVLYAISGNASENFENQMKSSSNQNQKIIVLQDKIAQLYDENDKLKRQQLQSLDDFIEI 2002

Query: 1392 X-XRVNDA------EAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEY 1444
               + +D       E + L+   +     SE+  +       L ++++E +N+++    Y
Sbjct: 2003 SPLKESDLIKQLRQEIETLKADKEQGRAKSELQLEIVNLEKKLIKKDEEMQNIKKGTYMY 2062

Query: 1445 EKRIEDLTYEKESELAILRLKMHENANH----------YETMQKESEIERVKLIE-ELNV 1493
                E    +    +  L       AN           YE +Q E    +  + E +L +
Sbjct: 2063 IDMCEKAIVQDRDWMIDLNSLEERQANRWRIVCEKLVEYEQLQGEIMKNQNDIQELQLQL 2122

Query: 1494 KITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSK 1553
            K  E++S+   + + +++L+EE   +     +   QE+E   L  E + L++ +++    
Sbjct: 2123 KNKENLSIKSMIMKQSQSLDEEDIFSIRSTVSKLRQELEQEKL--ENSKLKSYLKSYLKD 2180

Query: 1554 IQKHVSFASDTKQGRDEQLDNTMNKELLDAV 1584
             Q+        KQ +++++    NK L + +
Sbjct: 2181 EQRFEVSNRQIKQEQNQRVKEE-NKSLRNRI 2210



 Score =  121 bits (291), Expect = 2e-25
 Identities = 227/1161 (19%), Positives = 501/1161 (43%), Gaps = 135/1161 (11%)

Query: 475  VNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHK 534
            +N I  +++   QEL  E K+  ++D+++KL   +E   ++ DE+      + K K  ++
Sbjct: 106  INSILYLKQSKLQEL--ESKEQKMRDILQKLLKKQESKEKI-DEVKNILTFIAKEKQKYQ 162

Query: 535  LKL-----------KQMQKTIDNFSKVS-----------DSNKEIVRLTEELHHLSQKVA 572
            LKL           K+ QK +  +  V            D  K      + ++ LS  + 
Sbjct: 163  LKLPDNSLQQNNLSKEYQKIVTKYESVMIQINRLNQLIFDQIKPAYTCEDSIYQLSYNIK 222

Query: 573  ELEEEKGNLQLHLVDYDSGRMIES---DVYKKMIEMENLAETRLK--------------A 615
            E+ ++  N+Q  +   +     +S   + YKK IE +N     LK               
Sbjct: 223  EIIKQNSNVQKEIKQKEEESTKQSNKLEKYKKQIEQKNSQIDSLKMDVKNLNQQLQNQET 282

Query: 616  ISLL------ESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQID 669
            I+ L      +SQ+ D++Q+  I Q K  E  + +    Q + +Q+  EIK +   E++ 
Sbjct: 283  INSLNDCIKKQSQQIDILQQQIIEQNKILEQNETIIAKQQEKENQLFQEIKMIKC-EKVK 341

Query: 670  ALSASKKE---LALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQ----NYIQENMDLTD 722
            +L   + +       I +L+ +  +L   ++++  ++  +  +       + +  + +T+
Sbjct: 342  SLQQDEDDQIKYKNTINDLRQEINELNAQLENMYTEQAQLQQQFDEQEIEHKKSQIQMTN 401

Query: 723  KLEKMSAE--KISELLA--KINHEEQSKIQTQFGIDAKIQERDLYIEN-IESELSKYKSR 777
             ++K   E  K  +L+   KI   +Q K Q Q     +IQ+  +  +N I+++LS+Y   
Sbjct: 402  TIQKFQLEVKKYQQLVEDNKIQFNQQLKQQQQ--QHKQIQQELINNQNSIQNQLSEY--- 456

Query: 778  ICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVV 837
              ++ E++   E+    LE   D L   +++K     + T     L +     M  +   
Sbjct: 457  -LQIIENLKSKENLNQVLENLIDNLNLVIKQKLLQNLKST---SSLASSPMRGMSKNSSP 512

Query: 838  EKQLLEIEHENK-ELQKKNQIL--LEENQNLQISLSDMQQHYNALVEKANRTDLAESEST 894
             +Q+L   + N+ +LQK +  L  + E    +++L   +   N  + +     + ES+ T
Sbjct: 513  VRQILNHNNNNQIDLQKIHSTLDNISEQFLNRLNLLIKKDEKNQELIQHYCQQIEESQQT 572

Query: 895  KYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNI 954
              Q    D +   + IT   + L ++K  ++++ +  F+ + +S I      N + ++ I
Sbjct: 573  -IQQLCDDNDQQKQFITQMCKILNIEKIDDLKERK-SFSKEDQSYIETLNQNNAQIQQLI 630

Query: 955  EYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQ-----QTQSPDYTEQYIN 1009
             Y  +L+  +Q+ +  I++  + ++ L K  ++ + +  + Q     Q  SP  + +  +
Sbjct: 631  SYNQELQQDIQQQQIIIKDYEIQIDHL-KNQIKYLSQEKEDQCKFTTQIASPTQSSRKDS 689

Query: 1010 EINKL-NALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVS 1068
             I  L N  ++ +D++I  LN KI+   +   ++    ES++    ++ E ++    +V 
Sbjct: 690  IIKILQNEEIQNRDQQISELNDKISILDIEISNLQHQLESQIKLVQSRNEEIQHLNSQV- 748

Query: 1069 KQLLDSKQHNEEL--------QILVREQDDQIKELK-------ETKLTFE-MNIPKTEGM 1112
            + LL+ +Q+ E+L        Q    +Q+ QI +L+            F+ +  P  +  
Sbjct: 749  RDLLEKQQYFEQLINELNAYHQQSKNQQEVQIIKLEGVSYDISHNSFNFDALRTPTNQNY 808

Query: 1113 IISSTIEPMSDD---ANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQ 1169
            II    +  S +   ++ V             L  Q+EE  IQ+  ++QE+   L  + +
Sbjct: 809  IIDEIQQEQSINSSLSSIVQMSPNTQIKQIIQLNKQQEENIIQKNRLIQEKEVDLEKQNE 868

Query: 1170 ECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVD 1229
            E    + QL+++N +          Q+ QL  K+E L  E   +     E    +     
Sbjct: 869  E----LQQLQSINAKNEQEINELNLQLTQLHEKIETLREEQTQIQQQNDEYTKKL-VIEK 923

Query: 1230 QRGFEIAELWKQHLAQREA--DFQKTE-HELRVQLSAFESKYEQLLDSVQSSTQEETNKI 1286
            Q   +  EL+K+ + Q ++  D   T+  ELR+QL   + +   L ++ Q   Q++  +I
Sbjct: 924  QSAIDQIELYKKEIQQVKSINDQLSTQIAELRIQLQTNQEEQITLTENEQ-IIQQQNKEI 982

Query: 1287 VTMEQVTS-LQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXX 1345
              ++ + +  Q ++  ++  L+NL+E       Q + L+S+ ++  +             
Sbjct: 983  QFLKTINNEKQIQISQQDYQLQNLKE-------QFDHLKSKSKNLIIKTNSAIKEIKIIH 1035

Query: 1346 XXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVN--DAEAKVL 1403
                  ++        +QEQ +L  + +  + K  +            +V   ++E  ++
Sbjct: 1036 AEELQQIKV-----NLLQEQQLLKYDMKQLETKFVAIEQSYQSKIYNAQVKILESEQSIV 1090

Query: 1404 ELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILR 1463
            +   +L+L      Q   +Y     +  ++ + + QQ  + + +   L  +KE +L  + 
Sbjct: 1091 QFQEELKLLQQSKLQIEEKYCKAQDEFLEQSQFIDQQNTKLKSQKSQLE-QKEKQLQCIE 1149

Query: 1464 LKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQ 1523
            +++ E ++H E   + ++  +++ I +L   +++ +     + +LN+       + +E Q
Sbjct: 1150 IQIQEQSDHIEQSNQTTKTLQLE-INQLQQILSQQLQEKNLIHDLNQ-------QNSEKQ 1201

Query: 1524 TALENQEIEIVTLNDEITNLQ 1544
              L+ +E ++  L+ E+ NLQ
Sbjct: 1202 QLLQQKEQQLKVLHSELENLQ 1222



 Score = 96.3 bits (229), Expect = 6e-18
 Identities = 179/917 (19%), Positives = 402/917 (43%), Gaps = 80/917 (8%)

Query: 212  EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271
            +D K+++ K Q N I    +++ +  +L +++ +KD ++  L E   +      +I  ++
Sbjct: 1343 DDLKKEIQKAQ-NLIDQNIKYEQDIIQLKQNLTTKDQQLVGLNEQLNVSIKQNQDIQSQY 1401

Query: 272  SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELL 331
            +    +LE+                 Q I    E++  ++++  L   N+ E  +     
Sbjct: 1402 TLKVTQLEKQIINLEREKLLLNESNDQLIR---EKQNNLQQQ--LTKQNLNEEKENATSS 1456

Query: 332  EHLNCQIR--QTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWS-Q 388
            + +  Q    Q  KE EN      +  K +     + S  I + +  N    ++   S Q
Sbjct: 1457 QEVKIQQLKDQLQKEQENIKQLQDSHQKQIQQYFNEKSQQIQQLTSNNDNLTLQLNESKQ 1516

Query: 389  LSSETLNQ-DTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDT 447
            +S+E LN  D  K I  N++ +++   Q++ +     + V S+ +               
Sbjct: 1517 ISNEHLNDNDKLKSIINNQLTQIKQFEQAIIQYKNQLQDVKSQNENLVTILHQSENKWTN 1576

Query: 448  LIAQ-----LQLEHQQHMEGPSLIHVGTNTEDVNE--IAKVQEQLKQ-ELNDEI------ 493
            L  Q     L ++ Q+H      + + T  E + +  I  V ++ K  E+N+++      
Sbjct: 1577 LNEQNTQYKLSIQQQEHQIQQQSLLILTQEEALKKQIIINVDQEKKLFEINNQLWQEQQV 1636

Query: 494  -KDVNVKDLIEKLKSAE-------EQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTID 545
             +D+N+    +KL+ ++       +Q+ QL D+++     +  +KS +  +L+++ +  +
Sbjct: 1637 SEDLNLNKQ-KKLEQSQRDNDLLLQQVKQLQDKLNECQNELQVLKSENN-QLRELSE--E 1692

Query: 546  NFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSG-RMIESDVYKKMIE 604
            N ++             ++  L   ++E EE++G+    + +  +  + + ++  K+ + 
Sbjct: 1693 NINQTQSIKALYQNQLFQISELRNDLSESEEKEGSNLKRIEELTNQLQNVLAEKEKQRLN 1752

Query: 605  MENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHL 664
             E      LK   L+E      +Q   + Q    ++E    +I+QL  ++   EIK   L
Sbjct: 1753 QEAGVNGILKEKQLIE------IQLNEVTQTGLKQIEQYKQEIAQLNQEK--EEIKK-QL 1803

Query: 665  EEQIDALSASKKELALVIENLKLD--------KEQLYGTIKDLENDKEDIMNKLQNYIQE 716
            E+ ++     ++EL   + N++L+        K++ Y   K +E+ +  ++ ++Q   Q+
Sbjct: 1804 EDNLEKKKQVEEELNQKVNNIRLEFQLEIDQLKQKQYENQKAIEDQQNQLIIQVQQEKQQ 1863

Query: 717  NMDLTDKLEKMSAEKISELLA--KINHEEQ--SKIQTQFGIDAKIQERDLYIENIESELS 772
               L  ++ K+  +  +E+    ++ HE +   K  +Q  +D  +      IE  E +++
Sbjct: 1864 QNSLIAEINKIQNDFNNEMSKNQQLMHENKRLQKFLSQSNLDKDLMHDRQQIEQGEEKIN 1923

Query: 773  KYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMD 832
              +++  R + SI+  +     L   +       + + K+ S    +   L +++A L D
Sbjct: 1924 CDENKSLRQDNSISDRQQCVSVLYAISGNASENFENQMKSSSNQNQKIIVLQDKIAQLYD 1983

Query: 833  HDRVVEKQLLEIEHENKELQ--KKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAE 890
             +  +++Q L+   +  E+   K++ ++ +  Q ++   +D +Q   A  E        E
Sbjct: 1984 ENDKLKRQQLQSLDDFIEISPLKESDLIKQLRQEIETLKADKEQG-RAKSELQLEIVNLE 2042

Query: 891  SESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKY 950
             +  K   +++    N+K+ T+ +  +  +   +  D  I+ N+  E      +++ EK 
Sbjct: 2043 KKLIKKDEEMQ----NIKKGTYMYIDMCEKAIVQDRDWMIDLNSLEERQANRWRIVCEKL 2098

Query: 951  EKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINE 1010
               +EY  QL+ ++ + +N+I+ L + ++  NK NL +  K +  +Q+QS D  E+ I  
Sbjct: 2099 ---VEY-EQLQGEIMKNQNDIQELQLQLK--NKENLSI--KSMIMKQSQSLD--EEDIFS 2148

Query: 1011 INKLNALLKQKDEEIIALNQKINNAQVSYMS-----MVSDYESKLAQFTTKLENMEEEMQ 1065
            I    + L+Q+ E+    N K+ +   SY+       VS+ + K  Q     E  +    
Sbjct: 2149 IRSTVSKLRQELEQEKLENSKLKSYLKSYLKDEQRFEVSNRQIKQEQNQRVKEENKSLRN 2208

Query: 1066 RVSKQLLDSKQHNEELQ 1082
            R+S Q  + KQ NE++Q
Sbjct: 2209 RISDQQEEIKQLNEQIQ 2225



 Score = 87.0 bits (206), Expect = 4e-15
 Identities = 157/836 (18%), Positives = 350/836 (41%), Gaps = 74/836 (8%)

Query: 719  DLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRI 778
            D   KL+K      ++ + K + + Q+  +   G   K QER   ++ + S L      I
Sbjct: 4    DQIAKLQKDLQIYKNQQVDKFDSDHQNLNKLMQGYQRKAQERKAIMKQLYSILKTKDQEI 63

Query: 779  CRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVE 838
              L ++     D         D     +Q K+++ S+   QED++     V+     + +
Sbjct: 64   EELSQTFECQMD---------DMNNKMIQLKEQSDSQLFQQEDKIKQIEQVINSILYLKQ 114

Query: 839  KQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDL--------AE 890
             +L E+E + ++++   Q LL++ ++ +  + +++     + ++  +  L          
Sbjct: 115  SKLQELESKEQKMRDILQKLLKKQESKE-KIDEVKNILTFIAKEKQKYQLKLPDNSLQQN 173

Query: 891  SESTKYQTQLRDLESNLKRITHEHQTLIVQKKK--EIEDLEIEFNTQIESAIRDKKVLNE 948
            + S +YQ  +   ES + +I   +Q +  Q K     ED   + +  I+  I+    + +
Sbjct: 174  NLSKEYQKIVTKYESVMIQINRLNQLIFDQIKPAYTCEDSIYQLSYNIKEIIKQNSNVQK 233

Query: 949  KYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYI 1008
            + ++  E  T+   +L++YK  IE  N  ++ L KM+++ +++ +Q Q+T          
Sbjct: 234  EIKQKEEESTKQSNKLEKYKKQIEQKNSQIDSL-KMDVKNLNQQLQNQET---------- 282

Query: 1009 NEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVS 1068
              IN LN  +K++ ++I  L Q+I    +    ++   E+ +A+   K   + +E++ + 
Sbjct: 283  --INSLNDCIKKQSQQIDILQQQI----IEQNKILEQNETIIAKQQEKENQLFQEIKMIK 336

Query: 1069 KQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNV 1128
             + + S Q +E+ QI   +  + I +L++     E+N  + E M           D   +
Sbjct: 337  CEKVKSLQQDEDDQI---KYKNTINDLRQE--INELN-AQLENMYTEQAQLQQQFDEQEI 390

Query: 1129 DXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGH 1188
            +             K Q E +  Q+  ++++   + N +L++   +  Q + +  EL  +
Sbjct: 391  EHKKSQIQMTNTIQKFQLEVKKYQQ--LVEDNKIQFNQQLKQ---QQQQHKQIQQELINN 445

Query: 1189 DVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREA 1248
                Q Q+++    +E L ++ +NL   +  L  +++  + Q+  +  +      +    
Sbjct: 446  QNSIQNQLSEYLQIIENLKSK-ENLNQVLENLIDNLNLVIKQKLLQNLKSTSSLASSPMR 504

Query: 1249 DFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRN 1308
               K    +R Q+    +  +  L  + S+           EQ  +  N L  K+E  + 
Sbjct: 505  GMSKNSSPVR-QILNHNNNNQIDLQKIHSTLDN------ISEQFLNRLNLLIKKDEKNQE 557

Query: 1309 LQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSIL 1368
            L + Y   I + +    ++ D+                    D   E +S+ +  +  I 
Sbjct: 558  LIQHYCQQIEESQQTIQQLCDDNDQQKQFITQMCKILNIEKIDDLKERKSFSKEDQSYIE 617

Query: 1369 NINEENAQLKKSSXXXXXXXXXXXXR---VNDAEAKVLELTHQLEL----KDSEIYQKTH 1421
             +N+ NAQ+++              +   + D E ++  L +Q++     K+ +    T 
Sbjct: 618  TLNQNNAQIQQLISYNQELQQDIQQQQIIIKDYEIQIDHLKNQIKYLSQEKEDQCKFTTQ 677

Query: 1422 EYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESE 1481
              + T + R D    + Q   E + R + ++ E   +++IL +++  N  H    Q ES+
Sbjct: 678  IASPTQSSRKDSIIKILQN-EEIQNRDQQIS-ELNDKISILDIEI-SNLQH----QLESQ 730

Query: 1482 IERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEM-QTALENQEIEIVTL 1536
            I   KL++  N +I    S  + + E  +  E+ + + N   Q +   QE++I+ L
Sbjct: 731  I---KLVQSRNEEIQHLNSQVRDLLEKQQYFEQLINELNAYHQQSKNQQEVQIIKL 783



 Score = 70.1 bits (164), Expect = 5e-10
 Identities = 136/765 (17%), Positives = 313/765 (40%), Gaps = 77/765 (10%)

Query: 823  LVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEK 882
            L +++A L    ++ + Q  +++  + + Q  N+++    +  Q   + M+Q Y+ L  K
Sbjct: 2    LNDQIAKLQKDLQIYKNQ--QVDKFDSDHQNLNKLMQGYQRKAQERKAIMKQLYSIL--K 57

Query: 883  ANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRD 942
                ++ E   T ++ Q+ D+ + + ++  +  + + Q++ +I+ +E   N+ +      
Sbjct: 58   TKDQEIEELSQT-FECQMDDMNNKMIQLKEQSDSQLFQQEDKIKQIEQVINSILYLKQSK 116

Query: 943  KKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPD 1002
             + L  K +K  + + +L  + QE K  I+ +  N+       L  I K  QK Q + PD
Sbjct: 117  LQELESKEQKMRDILQKL-LKKQESKEKIDEVK-NI-------LTFIAKEKQKYQLKLPD 167

Query: 1003 YTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEE 1062
             + Q  N   +   ++ + +  +I +N ++N      +      E  + Q +  ++ + +
Sbjct: 168  NSLQQNNLSKEYQKIVTKYESVMIQIN-RLNQLIFDQIKPAYTCEDSIYQLSYNIKEIIK 226

Query: 1063 EMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISS-TIEPM 1121
            +   V K++   ++ + +    + +   QI++      + +M++      + +  TI  +
Sbjct: 227  QNSNVQKEIKQKEEESTKQSNKLEKYKKQIEQKNSQIDSLKMDVKNLNQQLQNQETINSL 286

Query: 1122 SDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETL 1181
            +D                    +++ +   Q  +++ +Q  K N   QE   K+I+ E +
Sbjct: 287  NDCIKKQSQQIDILQQQI----IEQNKILEQNETIIAKQQEKENQLFQEI--KMIKCEKV 340

Query: 1182 NTELTGHD--VVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELW 1239
             +     D  +  +  IN L+ ++ +LN + +N+ +  A+L         Q+ F+     
Sbjct: 341  KSLQQDEDDQIKYKNTINDLRQEINELNAQLENMYTEQAQL---------QQQFD----- 386

Query: 1240 KQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKL 1299
            +Q +  +++  Q T    + QL     KY+QL+         E NKI   +Q+   Q + 
Sbjct: 387  EQEIEHKKSQIQMTNTIQKFQLEV--KKYQQLV---------EDNKIQFNQQLKQQQQQH 435

Query: 1300 QDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSY 1359
            +  ++ L N Q     + NQ+      IE+ K                   +L  + +  
Sbjct: 436  KQIQQELINNQNS---IQNQLSEYLQIIENLK---SKENLNQVLENLIDNLNLVIKQKLL 489

Query: 1360 KQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQK 1419
            + ++  S L  +      K SS            +++      L+  H      SE +  
Sbjct: 490  QNLKSTSSLASSPMRGMSKNSSPVRQILNHNNNNQID------LQKIHSTLDNISEQFLN 543

Query: 1420 THEYTITLTQRNDEF-ENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQK 1478
                 I   ++N E  ++  QQ+ E ++ I+ L  + + +   +             M K
Sbjct: 544  RLNLLIKKDEKNQELIQHYCQQIEESQQTIQQLCDDNDQQKQFIT-----------QMCK 592

Query: 1479 ESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLND 1538
               IE++  ++E      E  S  + + + N  +++ ++   E+Q  ++ Q+I I     
Sbjct: 593  ILNIEKIDDLKERKSFSKEDQSYIETLNQNNAQIQQLISYNQELQQDIQQQQIIIKDYEI 652

Query: 1539 EITNLQNMVRASSSKIQKHVSF----ASDTKQGRDEQLDNTMNKE 1579
            +I +L+N ++  S + +    F    AS T+  R + +   +  E
Sbjct: 653  QIDHLKNQIKYLSQEKEDQCKFTTQIASPTQSSRKDSIIKILQNE 697



 Score = 48.4 bits (110), Expect = 0.002
 Identities = 95/518 (18%), Positives = 229/518 (44%), Gaps = 45/518 (8%)

Query: 216  QQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLA 275
            +++T   +N +A     + EKQRL     +++  ++ + +  +L+E    E++    K  
Sbjct: 1733 EELTNQLQNVLA-----EKEKQRL-----NQEAGVNGILKEKQLIEIQLNEVTQTGLK-- 1780

Query: 276  QELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANM-TELTKKIELLEHL 334
             ++EQ              + KQ +E + E+K ++EE+ + ++ N+  E   +I+ L+  
Sbjct: 1781 -QIEQYKQEIAQLNQEKEEIKKQ-LEDNLEKKKQVEEELNQKVNNIRLEFQLEIDQLKQK 1838

Query: 335  NCQIRQTNKELENKLATMGTESK----AVSSPSKKGSPLISRKSGRNTASKMKSPWSQLS 390
              + ++  ++ +N+L     + K    ++ +   K     + +  +N     ++   Q  
Sbjct: 1839 QYENQKAIEDQQNQLIIQVQQEKQQQNSLIAEINKIQNDFNNEMSKNQQLMHENKRLQKF 1898

Query: 391  SETLNQDTDKKINKNEIAKLEMVIQ-SLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLI 449
                N D D   ++ +I + E  I    NK L     +   +              +   
Sbjct: 1899 LSQSNLDKDLMHDRQQIEQGEEKINCDENKSLRQDNSISDRQQCVSVLYAISGNASENFE 1958

Query: 450  AQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELND--EIKDVNVKDLIEKLKS 507
             Q++    Q+ +   L        D N+  K++ Q  Q L+D  EI  +   DLI++L+ 
Sbjct: 1959 NQMKSSSNQNQKIIVLQDKIAQLYDEND--KLKRQQLQSLDDFIEISPLKESDLIKQLRQ 2016

Query: 508  AEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSK-----VSDSNKEIVRLTE 562
              E +    ++  A ++  +++ +  K KL +  + + N  K     +    K IV+  +
Sbjct: 2017 EIETLKADKEQGRAKSELQLEIVNLEK-KLIKKDEEMQNIKKGTYMYIDMCEKAIVQDRD 2075

Query: 563  ELHHLSQKVAELEEEKGN----LQLHLVDYD--SGRMI--ESDVYKKMIEMENLAETRLK 614
             +  L+     LEE + N    +   LV+Y+   G ++  ++D+ +  ++++N     +K
Sbjct: 2076 WMIDLN----SLEERQANRWRIVCEKLVEYEQLQGEIMKNQNDIQELQLQLKNKENLSIK 2131

Query: 615  AISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSAS 674
            ++ + +SQ  D  +++  ++    ++  +L +  +L++ ++ S +KS   +EQ   +S +
Sbjct: 2132 SMIMKQSQSLD-EEDIFSIRSTVSKLRQEL-EQEKLENSKLKSYLKSYLKDEQRFEVS-N 2188

Query: 675  KKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQN 712
            ++      + +K + + L   I D + + + +  ++QN
Sbjct: 2189 RQIKQEQNQRVKEENKSLRNRISDQQEEIKQLNEQIQN 2226


>UniRef50_A2FP55 Cluster: Viral A-type inclusion protein, putative;
            n=1; Trichomonas vaginalis G3|Rep: Viral A-type inclusion
            protein, putative - Trichomonas vaginalis G3
          Length = 1974

 Score =  141 bits (342), Expect = 1e-31
 Identities = 233/1160 (20%), Positives = 496/1160 (42%), Gaps = 116/1160 (10%)

Query: 472  TEDVNEIAKVQEQLKQEL----NDEIKDV-----NVKDLIEKLKSAEEQITQLNDEIDAA 522
            TE +  ++K  + L  +L    +D  +D+     + +  + + +  EE  +Q+  E+++ 
Sbjct: 80   TEQIAALSKKNQDLSAKLEMFTHDTTEDILPRADSPRRSVRRYEDDEENTSQMKFEMESL 139

Query: 523  NK-NMI---KV-KSNHKLKLKQMQ--KTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELE 575
             + N +   K+ K +H L+ K+ +  K ++N+ + S   +++    E+     +K+ E +
Sbjct: 140  QRENKVLTQKIEKLSHSLQNKKNREKKLVENYQQASQKFRDLRASYEQTTENYKKLLESK 199

Query: 576  EEKG--NLQL---HLVDYDSGRMIESDVYKKMIEMENLAETRLKAIS---LLESQKFDLV 627
            ++    N+++    +   D   M+E +  +   ++E L +T LK +S    LE++  +  
Sbjct: 200  KDDDIRNVEIMKQQIALNDEKHMLEKENTELKSKLEKLEQTNLKLVSENMALENKFTECA 259

Query: 628  QELHILQQKYDEVEDKLADISQLQSDQVCS-EIKSVHLEEQIDALSASKKELAL------ 680
            +    L+++YD++E   ++I+    +Q    E+   ++ + +     ++K L+       
Sbjct: 260  KGYQALKKEYDQLESAHSEINDKSEEQQKEVELLKANIVKVMKIQKRTEKNLSKAQDKCN 319

Query: 681  ----VIENLKLDKEQL--------------YGTIKDLENDKEDIMNKLQNYIQENMDLTD 722
                ++++   +KE +              Y  +KDLE++ +++    +   QEN DL  
Sbjct: 320  QQEQLLKSFNQEKENITKQLQECTGLLDKSYTRLKDLESNNKELSRVNKKLTQENEDLRG 379

Query: 723  KLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLE 782
              + + A   S++    + +     +T   + +++ +    I++ +++ +  +S++ +L+
Sbjct: 380  VNKNLKAA--SQISQSKDFQISKLNETINSLRSELDDTASKIKDSQNDATDLRSQLAQLQ 437

Query: 783  ESIAVMEDR--RYSLERKA--------DQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMD 832
            E    +E+R   Y  E KA         ++   +   Q    E    + E V   + L  
Sbjct: 438  EEKFELENRCKEYEQELKAANDKISKSKEMSQNINSMQSDLKELNKLKSENVELKSKLEI 497

Query: 833  HDRVVEK--QLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAE 890
            H +      Q  E+  EN EL++  +I  EE QN  +  + +    NA+ E  +  +   
Sbjct: 498  HSQKSFNRIQFEELRQENNELRETIRIAEEEEQNDTVHSNLL----NAIKEYYDENEELR 553

Query: 891  SESTKYQTQLRDLESNLKRITHEHQTLI-VQKKKEIEDLEIEFNTQIESAIRDKKV---L 946
              + K   QL+DL S L R  H++  L  +  K ++E+ E++ + + E  ++  KV   L
Sbjct: 554  KVNNKLTKQLKDLSSQLVRAQHQNMQLTDIINKSQLEEEELDSDEECEKLLKSPKVKTVL 613

Query: 947  NEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQ 1006
            NE     +E   +L  Q++E K   E L  N    ++     +    ++ Q    D+ E 
Sbjct: 614  NELNSSLLEN-KELRRQVKELKQENEQLKQNSRLNDEEESPEVKLSEEEDQIFEEDFPEV 672

Query: 1007 YINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQR 1066
             ++E N  N+  ++ D E+I +  KI   Q  Y  ++ D ES  A+    LE ++ E + 
Sbjct: 673  ELDESN--NSPEEKSDSELIPI--KIE-PQFIYNKIIDDEESN-AESDDNLEEVKSEEED 726

Query: 1067 VSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMI--ISSTIEPMSDD 1124
             + +  ++ +++EE         +  +  +E   + E N   +E     IS   +  +D 
Sbjct: 727  ANLEENNNSENSEENNNSEENNSEGSENSEENNNSEENNSEHSENSEEDISEEEKTKNDL 786

Query: 1125 ANNVDXXXXXXXXXXXXLKVQEEEEFI--QERSVLQEQSAKLNTELQECYTKIIQLETLN 1182
               +             +K QEE++ +  +E + + E + KLN+ ++    ++  L   N
Sbjct: 787  IQQIGDLQKKVYFLNNGIKSQEEQKDVLHKENNQIIEHNEKLNSAVETLKRELSTLNLEN 846

Query: 1183 TELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRS-SISSAVDQRGFEIAELWKQ 1241
             ++   +    ++I +LK ++E+L     NL     E++S    +  D+  +   E    
Sbjct: 847  EKIIEDNENKDKEIERLKEEIEKLKNHEMNLDELEKEIKSLEQENDDDEVNYLKKETEDL 906

Query: 1242 HLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQD 1301
                +E  F+  + +L  ++   E +   L+++ Q+  +EE         + SL+ ++ +
Sbjct: 907  EKMAKEVIFRNEKIQLEQKIRDLEEENRLLIENYQNGHEEEN--------LDSLEAQMTE 958

Query: 1302 KEEHLRNLQEKYADVINQIEILRS-EIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYK 1360
              E  + L  +  +VI++ E   S E+E+ K AF                   T +    
Sbjct: 959  LMEMNQKLSRELDEVISKKENESSIEVEELKNAFTEANKQKEQVLKQYNTLKATYSLLLT 1018

Query: 1361 QMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKT 1420
            Q  +    N  E+  + + S               N    K LEL     + DS+  +  
Sbjct: 1019 QYNDLKDQNNFEKVTETETSEIQSLKEENEKLKAYN----KSLELKF---MNDSDNVRFA 1071

Query: 1421 HEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEK-ESELAILRLKMHENANHYETMQKE 1479
            HE T          E ++Q++  YE++I+ L  EK E E    RL    +    E +++E
Sbjct: 1072 HEET----------EKLKQKVTNYEEKIKTLEKEKKEHETEEQRL----SGKLKEFIKQE 1117

Query: 1480 SEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDE 1539
             +     L+        E  +L K + +LN  L++   +  + +  + N+E EI      
Sbjct: 1118 EDFG--VLLGNYKKLNEEKTNLEKSLNKLNDDLQKVTKENEKNKIIISNRETEISMYQHA 1175

Query: 1540 ITNLQNMVRASSSKIQKHVS 1559
             T  QN +   + ++Q  V+
Sbjct: 1176 NTAQQNDLARENQQLQNQVT 1195



 Score =  141 bits (341), Expect = 2e-31
 Identities = 269/1333 (20%), Positives = 557/1333 (41%), Gaps = 120/1333 (9%)

Query: 311  EEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLI 370
            +EK  LE  N TEL  K+E LE  N ++   N  LENK       +K   +  K+   L 
Sbjct: 218  DEKHMLEKEN-TELKSKLEKLEQTNLKLVSENMALENKFTEC---AKGYQALKKEYDQLE 273

Query: 371  SRKSGRNTASKMKSPWSQLSSET------LNQDTDKKINK--NEIAKLEMVIQSLNKDLV 422
            S  S  N  S+ +    +L          + + T+K ++K  ++  + E +++S N++  
Sbjct: 274  SAHSEINDKSEEQQKEVELLKANIVKVMKIQKRTEKNLSKAQDKCNQQEQLLKSFNQEKE 333

Query: 423  DKEYVISEKDTXXXXXXXXXXGKDTLIAQL-QLEHQQHMEGPSLIHVGTNTEDVNEIAKV 481
            +    + E               ++   +L ++  +   E   L  V  N +  ++I++ 
Sbjct: 334  NITKQLQECTGLLDKSYTRLKDLESNNKELSRVNKKLTQENEDLRGVNKNLKAASQISQS 393

Query: 482  QEQLKQELNDEIKDV--NVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQ 539
            ++    +LN+ I  +   + D   K+K ++   T L  ++    +   ++++  K   ++
Sbjct: 394  KDFQISKLNETINSLRSELDDTASKIKDSQNDATDLRSQLAQLQEEKFELENRCKEYEQE 453

Query: 540  MQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVY 599
            ++   D  SK  + ++ I  +  +L  L++  +E  E K  L++H     S   I+ +  
Sbjct: 454  LKAANDKISKSKEMSQNINSMQSDLKELNKLKSENVELKSKLEIH--SQKSFNRIQFEEL 511

Query: 600  KKMIEMENLAETRLKAISLLESQKFDLVQE--LHILQQKYDEVEDKLADISQLQSDQVCS 657
            ++  E   L ET   A    E ++ D V    L+ +++ YDE E+ L  +    ++++  
Sbjct: 512  RQ--ENNELRETIRIA---EEEEQNDTVHSNLLNAIKEYYDENEE-LRKV----NNKLTK 561

Query: 658  EIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYG---TIKDLENDK-EDIMNKLQNY 713
            ++K   L  Q+        +L  +I   +L++E+L       K L++ K + ++N+L + 
Sbjct: 562  QLKD--LSSQLVRAQHQNMQLTDIINKSQLEEEELDSDEECEKLLKSPKVKTVLNELNSS 619

Query: 714  IQENMDLTDKLEKMSAEKIS-ELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELS 772
            + EN +L  +++++  E    +  +++N EE+S        + +I E D     +E + S
Sbjct: 620  LLENKELRRQVKELKQENEQLKQNSRLNDEEESPEVKLSEEEDQIFEED--FPEVELDES 677

Query: 773  KYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMD 832
                      E I +  + ++   +  D       E+  A S+  ++E +     A L +
Sbjct: 678  NNSPEEKSDSELIPIKIEPQFIYNKIID------DEESNAESDDNLEEVKSEEEDANLEE 731

Query: 833  HDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALV--EKANRTDLAE 890
            ++     +      EN     +N    EEN N + + S+  ++    +  E+  + DL +
Sbjct: 732  NNNSENSEENNNSEENNSEGSENS---EENNNSEENNSEHSENSEEDISEEEKTKNDLIQ 788

Query: 891  SESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKY 950
             +    Q ++  L + +K    +   L  +  + IE  E + N+ +E+  R+   LN + 
Sbjct: 789  -QIGDLQKKVYFLNNGIKSQEEQKDVLHKENNQIIEHNE-KLNSAVETLKRELSTLNLEN 846

Query: 951  EKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINE 1010
            EK IE     + +++  K  IE L     + ++MNL+ ++K ++  + ++ D     +N 
Sbjct: 847  EKIIEDNENKDKEIERLKEEIEKL-----KNHEMNLDELEKEIKSLEQENDD---DEVNY 898

Query: 1011 INKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQ 1070
            + K    L++  +E+I  N+KI   Q+       + E++L     +  + EE +  +  Q
Sbjct: 899  LKKETEDLEKMAKEVIFRNEKI---QLEQKIRDLEEENRLLIENYQNGHEEENLDSLEAQ 955

Query: 1071 LLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDX 1130
            + +  + N++L    RE D+ I + KE + + E+   K      +   E +    N +  
Sbjct: 956  MTELMEMNQKLS---RELDEVISK-KENESSIEVEELKNAFTEANKQKEQVLKQYNTLKA 1011

Query: 1131 XXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDV 1190
                       LK Q   E + E    + QS K   E  + Y K ++L+ +N      D 
Sbjct: 1012 TYSLLLTQYNDLKDQNNFEKVTETETSEIQSLKEENEKLKAYNKSLELKFMN------DS 1065

Query: 1191 VNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADF 1250
             N    ++   KL+Q  T  +  + T+ + +    +   +   ++ E  KQ     E DF
Sbjct: 1066 DNVRFAHEETEKLKQKVTNYEEKIKTLEKEKKEHETEEQRLSGKLKEFIKQ-----EEDF 1120

Query: 1251 ---QKTEHELRVQLSAFESKYEQLLDSVQSSTQE-ETNKIVTMEQVTSLQNKLQDKEEHL 1306
                    +L  + +  E    +L D +Q  T+E E NKI+   + T +           
Sbjct: 1121 GVLLGNYKKLNEEKTNLEKSLNKLNDDLQKVTKENEKNKIIISNRETEISMYQHANTAQQ 1180

Query: 1307 RNLQEKYADVINQIEILRSEIE--DEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQE 1364
             +L  +   + NQ+  L+ E+    +KV                   L  E    +Q  +
Sbjct: 1181 NDLARENQQLQNQVTSLQKEVTSLQDKVTSLQTSNGDNSDAEDTINGLEAEITDLQQKFD 1240

Query: 1365 QSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELT---HQL-----ELKDSEI 1416
                +  EE +  +K                 +    + +LT    QL     +LK S+ 
Sbjct: 1241 NLTEDFEEEKSSHEKDVEELSQTIEGLNKLCEEQHNTISQLTLKASQLQSEIDQLKPSDS 1300

Query: 1417 YQKTHEYTITL-------TQRN-DEFENVRQQLVEYEKRIEDLTYEKE-----------S 1457
             +    Y++ +        Q N +E EN+ +Q  E  K  E+   E+E           +
Sbjct: 1301 SKPKPNYSVFVKLDLEKPEQPNFNEEENLNEQNEEENKEEEEENKEEEENQNNEEEDDDN 1360

Query: 1458 ELAILRLKMHENANHYETMQKE-SEIERVKLIEELNVKITESVSLNKQVAELNKALEEEV 1516
            +  +L  ++ E +     ++K+ +++E+ K  E  +     ++    ++ E N  ++ ++
Sbjct: 1361 DNEMLMYQIQEQSREISKLKKQLNKLEKDK--ENADAAFKTAMDRVHELEEENTLMKHKI 1418

Query: 1517 AK--TNEMQTALENQEIEIVTLNDEITNLQNMVRAS-SSKIQKHVSFASDTK---QGRDE 1570
                  E + +LE  + +I  L  E + LQ  V +  S+ +Q+   FA + +   Q +D 
Sbjct: 1419 DSDGVKEDKPSLEEMKGKIDLLEYENSKLQQQVSSQPSTPVQQKNDFAENIEEQIQQKDS 1478

Query: 1571 QLDNTMNKELLDA 1583
            +++  + +EL DA
Sbjct: 1479 EIEK-LKEELADA 1490



 Score =  136 bits (328), Expect = 6e-30
 Identities = 256/1228 (20%), Positives = 517/1228 (42%), Gaps = 104/1228 (8%)

Query: 140  QLGD----VTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTX 195
            Q+GD    V  L+N IK ++    VL  +       I++  EK+N   + ++ +      
Sbjct: 789  QIGDLQKKVYFLNNGIKSQEEQKDVLHKE----NNQIIEHNEKLNSAVETLKRELSTLNL 844

Query: 196  XXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESK--DVRISSL 253
                            E  K+++ K++ + + +     DE ++ +K +E +  D  ++ L
Sbjct: 845  ENEKIIEDNENKDKEIERLKEEIEKLKNHEMNL-----DELEKEIKSLEQENDDDEVNYL 899

Query: 254  EEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEK 313
            ++  + LE    E+   + K+  +LEQ              L  ++ +   EE    E  
Sbjct: 900  KKETEDLEKMAKEVIFRNEKI--QLEQKIRDLEEENR----LLIENYQNGHEE----ENL 949

Query: 314  GSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRK 373
             SLE A MTEL   +E+ + L+ ++ +   + EN+ +    E K   + + K    + ++
Sbjct: 950  DSLE-AQMTEL---MEMNQKLSRELDEVISKKENESSIEVEELKNAFTEANKQKEQVLKQ 1005

Query: 374  SGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDT 433
               NT     S      ++  +Q+  +K+ + E ++++ + +  N+ L      +  K  
Sbjct: 1006 Y--NTLKATYSLLLTQYNDLKDQNNFEKVTETETSEIQSLKEE-NEKLKAYNKSLELKFM 1062

Query: 434  XXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEI 493
                       +   + Q    +++ ++          TE+     K++E +KQE +  +
Sbjct: 1063 NDSDNVRFAHEETEKLKQKVTNYEEKIKTLEKEKKEHETEEQRLSGKLKEFIKQEEDFGV 1122

Query: 494  KDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVK---SNHKLKLKQMQKTIDNFSKV 550
               N K L E+  + E+ + +LND++    K   K K   SN + ++   Q    N ++ 
Sbjct: 1123 LLGNYKKLNEEKTNLEKSLNKLNDDLQKVTKENEKNKIIISNRETEISMYQHA--NTAQQ 1180

Query: 551  SDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVD----YDSGRMIESDVYKKMIEME 606
            +D  +E  +L  ++  L ++V  L+++  +LQ    D     D+   +E+++     + +
Sbjct: 1181 NDLARENQQLQNQVTSLQKEVTSLQDKVTSLQTSNGDNSDAEDTINGLEAEITDLQQKFD 1240

Query: 607  NLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEE 666
            NL E   +  S  E    +L Q +  L +  +E  + ++ ++ L++ Q+ SEI  +   +
Sbjct: 1241 NLTEDFEEEKSSHEKDVEELSQTIEGLNKLCEEQHNTISQLT-LKASQLQSEIDQLKPSD 1299

Query: 667  QIDALSASKKELALVIENLK---LDKEQLYGTIKDLENDKEDIMNK----LQNYIQENMD 719
                       + L +E  +    ++E+      + EN +E+  NK     QN  +E+ D
Sbjct: 1300 SSKPKPNYSVFVKLDLEKPEQPNFNEEENLNEQNEEENKEEEEENKEEEENQNNEEEDDD 1359

Query: 720  LTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRIC 779
              +++     ++ S  ++K+  +     + +   DA  +     +  +E E +  K +I 
Sbjct: 1360 NDNEMLMYQIQEQSREISKLKKQLNKLEKDKENADAAFKTAMDRVHELEEENTLMKHKI- 1418

Query: 780  RLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEK 839
               +S  V ED+  SLE    ++     E  K   + + Q    V +     D    +E+
Sbjct: 1419 ---DSDGVKEDKP-SLEEMKGKIDLLEYENSKLQQQVSSQPSTPVQQ---KNDFAENIEE 1471

Query: 840  QLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRT-DLAESESTKYQT 898
            Q   I+ ++ E++K  + L +  ++L+ +L+ +     +L   +++T D  E +    ++
Sbjct: 1472 Q---IQQKDSEIEKLKEELADAKEDLKYALAKLDDANTSLTLNSSQTKDEEEDDLESLKS 1528

Query: 899  QLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYE------K 952
            Q+ +LE        + + L  +K KE+      F  QIE     K  + +KY+      K
Sbjct: 1529 QVNELEEQRDFYIKKSENL-EEKVKELTRKVTNFKPQIEETKTPKSNIEDKYQNLQTVNK 1587

Query: 953  NI-EYVTQLEAQL----QEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQY 1007
             + E ++  E Q+     + KN  E +  N  E+NK+ +E  D  ++ Q  QS D    +
Sbjct: 1588 GLAEEISAKEKQIDLLNSQIKNKEEQIKQNESEINKLFVEKNDLKIKLQ--QSSDELAAF 1645

Query: 1008 INEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRV 1067
              E +++    ++KDE +           VSY     + + K+ +   + + + E+    
Sbjct: 1646 KRERSEVK---REKDEAVKKCQDLEKVLAVSY-----EQDDKIQELERENQKLNEQYLFA 1697

Query: 1068 SKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPK--TEGMIISSTIEPMSDDA 1125
            + Q  DS +  +ELQ   +E  ++I  L+   L  E  + +   E   +   +     D 
Sbjct: 1698 ADQCKDSNKQRDELQKENKELIEKINNLENDLLQAEKELDELTDEKEKLEEELSQAKKDL 1757

Query: 1126 NNVDXXXXXXXXXXXXLKVQ--EEEEFIQERSV----LQEQSAKLNTELQECYTKIIQLE 1179
            +               +K Q  E+E  I E+SV    L  Q+ KLN E++E   +  + E
Sbjct: 1758 SQSKRQLQESKDDLFQIKKQMAEKERTISEQSVSIEDLGNQNDKLNEEIEEIQKEKDENE 1817

Query: 1180 TLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAEL---RSSISSAVDQRGFEIA 1236
                +L     + Q + + LKS+  QL  + DNL + + E       I   +     ++A
Sbjct: 1818 EKLKDLQEKLKIAQSKADSLKSQNNQLIKDRDNLQNQLNEFLLDGGKIDEKLVSENKQLA 1877

Query: 1237 ELWKQHLAQREADFQKTEHELRVQLSAFES-KYEQLLDSVQSSTQEETNKIVTMEQVTSL 1295
            E  K  + Q  A  +  E   RV   A E    E+ ++S+Q S  +  NK     Q+  L
Sbjct: 1878 E--KVQILQAHA-IKNIEGGSRVSAKAEEDPALERKVESLQVSL-DGANK-----QIQEL 1928

Query: 1296 QNKLQDKEEHLRNLQEKYADVINQIEIL 1323
            Q K  +  E    L+ K ++ I +  +L
Sbjct: 1929 QKKNNELNELNGVLRSKLSNAIKEKTLL 1956



 Score =  125 bits (301), Expect = 1e-26
 Identities = 181/963 (18%), Positives = 422/963 (43%), Gaps = 71/963 (7%)

Query: 665  EEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKL 724
            + QI +L+   ++L   + +       L  T  DL+ D+  +  ++    ++N DL+ KL
Sbjct: 38   QTQIKSLTDQVQDLEARLSSPTKTDTSLVKTCNDLQKDRSKLTEQIAALSKKNQDLSAKL 97

Query: 725  EKMSAEKISELLAKINH----------EEQSKIQTQFGIDAKIQERDLYIENIES---EL 771
            E  + +   ++L + +           +E++  Q +F +++  +E  +  + IE     L
Sbjct: 98   EMFTHDTTEDILPRADSPRRSVRRYEDDEENTSQMKFEMESLQRENKVLTQKIEKLSHSL 157

Query: 772  SKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLM 831
               K+R  +L E+      +   L    +Q     ++  ++  +  I+  E++ +   L 
Sbjct: 158  QNKKNREKKLVENYQQASQKFRDLRASYEQTTENYKKLLESKKDDDIRNVEIMKQQIALN 217

Query: 832  DHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAES 891
            D   ++EK+  E++ + ++L++ N  L+ EN  L+   ++  + Y AL ++ ++ + A S
Sbjct: 218  DEKHMLEKENTELKSKLEKLEQTNLKLVSENMALENKFTECAKGYQALKKEYDQLESAHS 277

Query: 892  E----STKYQTQLRDLESNLKRI------THEHQTLIVQKKKEIEDLEIEFNTQIESAIR 941
            E    S + Q ++  L++N+ ++      T ++ +    K  + E L   FN + E+  +
Sbjct: 278  EINDKSEEQQKEVELLKANIVKVMKIQKRTEKNLSKAQDKCNQQEQLLKSFNQEKENITK 337

Query: 942  DKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSP 1001
              +      +K+   +  LE+  +E     + L    E+L  +N  L       Q +QS 
Sbjct: 338  QLQECTGLLDKSYTRLKDLESNNKELSRVNKKLTQENEDLRGVNKNL---KAASQISQSK 394

Query: 1002 DYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENME 1061
            D+    +NE   +N+L  + D+    +    N+A     S ++  + +  +   + +  E
Sbjct: 395  DFQISKLNE--TINSLRSELDDTASKIKDSQNDA-TDLRSQLAQLQEEKFELENRCKEYE 451

Query: 1062 EEMQRVSKQLLDSKQHNEELQIL---VREQDDQIKELKETKLTFEMNIPKTEGMIISSTI 1118
            +E++  + ++  SK+ ++ +  +   ++E +    E  E K   E++  K+   I    +
Sbjct: 452  QELKAANDKISKSKEMSQNINSMQSDLKELNKLKSENVELKSKLEIHSQKSFNRIQFEEL 511

Query: 1119 EPMSDDANNVDXXXXXXXXXXXXLK--VQEEEEFIQERSVLQEQSAKLNTELQECYTKII 1176
               +++                     +   +E+  E   L++ + KL  +L++  ++++
Sbjct: 512  RQENNELRETIRIAEEEEQNDTVHSNLLNAIKEYYDENEELRKVNNKLTKQLKDLSSQLV 571

Query: 1177 QLETLNTELTGHDVVNQEQI--NQLKSKLE-QLNTENDNLLSTVAELRSSISSAVDQRGF 1233
            + +  N +LT  D++N+ Q+   +L S  E +   ++  + + + EL SS+    + R  
Sbjct: 572  RAQHQNMQLT--DIINKSQLEEEELDSDEECEKLLKSPKVKTVLNELNSSLLENKELRR- 628

Query: 1234 EIAELWKQH-LAQREADFQKTEHELRVQLS-----AFESKYEQL-LDSVQSSTQEET-NK 1285
            ++ EL +++   ++ +     E    V+LS      FE  + ++ LD   +S +E++ ++
Sbjct: 629  QVKELKQENEQLKQNSRLNDEEESPEVKLSEEEDQIFEEDFPEVELDESNNSPEEKSDSE 688

Query: 1286 IVTME-QVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXX 1344
            ++ ++ +   + NK+ D E       E  A+  + +E ++SE ED  +            
Sbjct: 689  LIPIKIEPQFIYNKIIDDE-------ESNAESDDNLEEVKSEEEDANL--EENNNSENSE 739

Query: 1345 XXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLE 1404
                  +  +E     +    S  N +E +   ++              ++ D + KV  
Sbjct: 740  ENNNSEENNSEGSENSEENNNSEENNSEHSENSEEDISEEEKTKNDLIQQIGDLQKKVYF 799

Query: 1405 LTHQLELKD--SEIYQKTHEYTITLTQR-NDEFENVRQQL----VEYEKRIEDLTYEKES 1457
            L + ++ ++   ++  K +   I   ++ N   E ++++L    +E EK IED    K+ 
Sbjct: 800  LNNGIKSQEEQKDVLHKENNQIIEHNEKLNSAVETLKRELSTLNLENEKIIED-NENKDK 858

Query: 1458 ELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVA 1517
            E+  L+ ++ +  NH E    E E E +K +E+ N    E   L K+  +L K  +E + 
Sbjct: 859  EIERLKEEIEKLKNH-EMNLDELEKE-IKSLEQEN-DDDEVNYLKKETEDLEKMAKEVIF 915

Query: 1518 KTNEMQTALENQEIEIVTLNDEITNLQN-MVRASSSKIQKHVSFASDTKQGRDEQLDNTM 1576
            +  ++Q   + +++E       I N QN     +   ++  ++   +  Q    +LD  +
Sbjct: 916  RNEKIQLEQKIRDLEEEN-RLLIENYQNGHEEENLDSLEAQMTELMEMNQKLSRELDEVI 974

Query: 1577 NKE 1579
            +K+
Sbjct: 975  SKK 977



 Score =  123 bits (297), Expect = 4e-26
 Identities = 296/1499 (19%), Positives = 613/1499 (40%), Gaps = 153/1499 (10%)

Query: 154  KDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXX------XXXXXXXXXX 207
            K N + V++++ K  E  +   Q+K N+++Q++++ N+                      
Sbjct: 294  KANIVKVMKIQ-KRTEKNLSKAQDKCNQQEQLLKSFNQEKENITKQLQECTGLLDKSYTR 352

Query: 208  XXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLL---KDIESKDVRISSLEEANKLLEAAR 264
                E   ++++++ +       + +   + L    +  +SKD +IS L   N+ + + R
Sbjct: 353  LKDLESNNKELSRVNKKLTQENEDLRGVNKNLKAASQISQSKDFQISKL---NETINSLR 409

Query: 265  FEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTEL 324
             E+    SK+     Q                K  +E  C+E  +  +  + +I+   E+
Sbjct: 410  SELDDTASKIKDS--QNDATDLRSQLAQLQEEKFELENRCKEYEQELKAANDKISKSKEM 467

Query: 325  TKKIEL----LEHLNCQIRQTNKELENKLATMGTES-KAVSSPSKKGSPLISRKSGRNTA 379
            ++ I      L+ LN +++  N EL++KL     +S   +     +      R++ R   
Sbjct: 468  SQNINSMQSDLKELN-KLKSENVELKSKLEIHSQKSFNRIQFEELRQENNELRETIRIAE 526

Query: 380  SKMKSPWSQLSSETLNQDTDKKINKNEIAK----LEMVIQSLNKDLVDKEYV------IS 429
             + ++    + S  LN   +      E+ K    L   ++ L+  LV  ++       I 
Sbjct: 527  EEEQN--DTVHSNLLNAIKEYYDENEELRKVNNKLTKQLKDLSSQLVRAQHQNMQLTDII 584

Query: 430  EKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQE- 488
             K              + L+   +++   +    SL+        V E+ +  EQLKQ  
Sbjct: 585  NKSQLEEEELDSDEECEKLLKSPKVKTVLNELNSSLLENKELRRQVKELKQENEQLKQNS 644

Query: 489  -LNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKL---KLKQM---Q 541
             LNDE +   VK   E+ +  EE   ++  E+D +N N  + KS+ +L   K++      
Sbjct: 645  RLNDEEESPEVKLSEEEDQIFEEDFPEV--ELDESN-NSPEEKSDSELIPIKIEPQFIYN 701

Query: 542  KTIDN--FSKVSDSNKEIVRLTEELHHLSQKV-AELEEEKGNLQLHLVDYDSGRMIESDV 598
            K ID+   +  SD N E V+  EE  +L +   +E  EE  N + +  + +     E + 
Sbjct: 702  KIIDDEESNAESDDNLEEVKSEEEDANLEENNNSENSEENNNSEEN--NSEGSENSEENN 759

Query: 599  YKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSE 658
              +    E+ +E   + IS  E  K DL+Q++  LQ+K   + + +    + Q D +  E
Sbjct: 760  NSEENNSEH-SENSEEDISEEEKTKNDLIQQIGDLQKKVYFLNNGIKSQEE-QKDVLHKE 817

Query: 659  IKSV--HLEEQIDALSASKKELA-LVIENLKL-------DKE--QLYGTIKDLENDK--- 703
               +  H E+   A+   K+EL+ L +EN K+       DKE  +L   I+ L+N +   
Sbjct: 818  NNQIIEHNEKLNSAVETLKRELSTLNLENEKIIEDNENKDKEIERLKEEIEKLKNHEMNL 877

Query: 704  EDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLY 763
            +++  ++++  QEN D      K   E + ++  ++    + KIQ +  I    +E  L 
Sbjct: 878  DELEKEIKSLEQENDDDEVNYLKKETEDLEKMAKEVIFRNE-KIQLEQKIRDLEEENRLL 936

Query: 764  IENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSY--------LQEKQKAYSE 815
            IEN ++     +  +  LE  +  + +    L R+ D++ S         ++E + A++E
Sbjct: 937  IENYQN--GHEEENLDSLEAQMTELMEMNQKLSRELDEVISKKENESSIEVEELKNAFTE 994

Query: 816  YTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQH 875
               Q+++++ +   L     ++  Q  +++ +N   +K  +    E Q+L+     ++ +
Sbjct: 995  ANKQKEQVLKQYNTLKATYSLLLTQYNDLKDQNN-FEKVTETETSEIQSLKEENEKLKAY 1053

Query: 876  YNALVEK-ANRTD---LAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIE 931
              +L  K  N +D    A  E+ K + ++ + E  +K +  E        KKE E  E  
Sbjct: 1054 NKSLELKFMNDSDNVRFAHEETEKLKQKVTNYEEKIKTLEKE--------KKEHETEEQR 1105

Query: 932  FNTQIESAIRDKK---VLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLEL 988
             + +++  I+ ++   VL   Y+K  E  T LE  L +  ++++ +    E+ NK+ +  
Sbjct: 1106 LSGKLKEFIKQEEDFGVLLGNYKKLNEEKTNLEKSLNKLNDDLQKVTKENEK-NKIIISN 1164

Query: 989  IDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSY------MSM 1042
             +  +   Q  +         E  +L   +    +E+ +L  K+ + Q S          
Sbjct: 1165 RETEISMYQHANTAQQNDLARENQQLQNQVTSLQKEVTSLQDKVTSLQTSNGDNSDAEDT 1224

Query: 1043 VSDYESKLAQFTTKLENM----EEEMQRVSKQLLDSKQHNEELQILVREQDDQIKEL--K 1096
            ++  E+++     K +N+    EEE     K + +  Q  E L  L  EQ + I +L  K
Sbjct: 1225 INGLEAEITDLQQKFDNLTEDFEEEKSSHEKDVEELSQTIEGLNKLCEEQHNTISQLTLK 1284

Query: 1097 ETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSV 1156
             ++L  E++  K      SS  +P      N                  EEE   ++   
Sbjct: 1285 ASQLQSEIDQLKPSD---SSKPKP------NYSVFVKLDLEKPEQPNFNEEENLNEQNEE 1335

Query: 1157 LQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQE-QINQLKSKLEQLNTENDNLLS 1215
              ++  + N E +E      + +  + E+  + +  Q  +I++LK +L +L  + +N  +
Sbjct: 1336 ENKEEEEENKEEEENQNNEEEDDDNDNEMLMYQIQEQSREISKLKKQLNKLEKDKENADA 1395

Query: 1216 TVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFE-SKYEQLLDS 1274
                    +    ++      ++    + + +   +  E + ++ L  +E SK +Q + S
Sbjct: 1396 AFKTAMDRVHELEEENTLMKHKIDSDGVKEDKPSLE--EMKGKIDLLEYENSKLQQQVSS 1453

Query: 1275 VQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAF 1334
              S+  ++ N         +++ ++Q K+  +  L+E+ AD    ++   ++++D   + 
Sbjct: 1454 QPSTPVQQKNDFAE-----NIEEQIQQKDSEIEKLKEELADAKEDLKYALAKLDDANTSL 1508

Query: 1335 XXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSIL---NINEENAQLK------------- 1378
                             L+++    ++ ++  I    N+ E+  +L              
Sbjct: 1509 TLNSSQTKDEEEDDLESLKSQVNELEEQRDFYIKKSENLEEKVKELTRKVTNFKPQIEET 1568

Query: 1379 KSSXXXXXXXXXXXXRVN-------DAEAKVLELTH-QLELKDSEIYQKTHEYTITLTQR 1430
            K+              VN        A+ K ++L + Q++ K+ +I Q   E      ++
Sbjct: 1569 KTPKSNIEDKYQNLQTVNKGLAEEISAKEKQIDLLNSQIKNKEEQIKQNESEINKLFVEK 1628

Query: 1431 ND---EFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERV-- 1485
            ND   + +    +L  +++   ++  EK+  +   +      A  YE   K  E+ER   
Sbjct: 1629 NDLKIKLQQSSDELAAFKRERSEVKREKDEAVKKCQDLEKVLAVSYEQDDKIQELERENQ 1688

Query: 1486 KLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQ 1544
            KL E+      +    NKQ  EL K  +E + K N ++  L   E E+  L DE   L+
Sbjct: 1689 KLNEQYLFAADQCKDSNKQRDELQKENKELIEKINNLENDLLQAEKELDELTDEKEKLE 1747



 Score =  111 bits (267), Expect = 2e-22
 Identities = 251/1382 (18%), Positives = 573/1382 (41%), Gaps = 102/1382 (7%)

Query: 220  KMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELE 279
            + Q   +  E E   +  RL  + ES +V++S  EE +++ E    E+ L+ S  + E E
Sbjct: 627  RRQVKELKQENEQLKQNSRLNDEEESPEVKLS--EEEDQIFEEDFPEVELDESNNSPE-E 683

Query: 280  QXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIR 339
            +              +  + I+   +E++  E   +LE     E    +E  E+ N +  
Sbjct: 684  KSDSELIPIKIEPQFIYNKIID---DEESNAESDDNLEEVKSEEEDANLE--ENNNSENS 738

Query: 340  QTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTD 399
            + N   E   +  G+E+   ++ S++ +   S  S  + + + K+  + L  +    D  
Sbjct: 739  EENNNSEENNSE-GSENSEENNNSEENNSEHSENSEEDISEEEKTK-NDLIQQI--GDLQ 794

Query: 400  KKIN--KNEIAKLEM---VIQSLNKDLVD-KEYVISEKDTXXXXXXXXXXGKDTLIAQLQ 453
            KK+    N I   E    V+   N  +++  E + S  +T            + +I   +
Sbjct: 795  KKVYFLNNGIKSQEEQKDVLHKENNQIIEHNEKLNSAVETLKRELSTLNLENEKIIEDNE 854

Query: 454  LEHQQHMEGPSLIHVGTNTE-DVNEIAKVQEQLKQELNDEIKDVN-VKDLIEKLKSAEEQ 511
             + ++       I    N E +++E+ K  + L+QE +D+  +VN +K   E L+   ++
Sbjct: 855  NKDKEIERLKEEIEKLKNHEMNLDELEKEIKSLEQENDDD--EVNYLKKETEDLEKMAKE 912

Query: 512  ITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKV 571
            +   N++I    K +  ++  ++L ++  Q   +    +     ++  L E    LS+++
Sbjct: 913  VIFRNEKIQLEQK-IRDLEEENRLLIENYQNGHEE-ENLDSLEAQMTELMEMNQKLSREL 970

Query: 572  AELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELH 631
             E+  +K N     V+       E++  K+ +  +    T     SLL +Q  DL  + +
Sbjct: 971  DEVISKKENESSIEVEELKNAFTEANKQKEQVLKQY--NTLKATYSLLLTQYNDLKDQNN 1028

Query: 632  ---ILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLD 688
               + + +  E++    +  +L++     E+K ++  + +       ++L   + N +  
Sbjct: 1029 FEKVTETETSEIQSLKEENEKLKAYNKSLELKFMNDSDNVRFAHEETEKLKQKVTNYEEK 1088

Query: 689  KEQLYGTIKDLENDKEDIMNKLQNYIQENMD---LTDKLEKMSAEK--ISELLAKINHEE 743
             + L    K+ E +++ +  KL+ +I++  D   L    +K++ EK  + + L K+N + 
Sbjct: 1089 IKTLEKEKKEHETEEQRLSGKLKEFIKQEEDFGVLLGNYKKLNEEKTNLEKSLNKLNDDL 1148

Query: 744  QSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIA----VMEDRRYSLERKA 799
            Q        +  + ++  + I N E+E+S Y+      +  +A     ++++  SL+++ 
Sbjct: 1149 QK-------VTKENEKNKIIISNRETEISMYQHANTAQQNDLARENQQLQNQVTSLQKEV 1201

Query: 800  DQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILL 859
              L   +   Q +  + +  ED +    A + D  +  +    + E E    +K  + L 
Sbjct: 1202 TSLQDKVTSLQTSNGDNSDAEDTINGLEAEITDLQQKFDNLTEDFEEEKSSHEKDVEELS 1261

Query: 860  EENQNLQISLSDMQQHYNALVEKANRTD-----LAESESTK----YQTQLR-DLESNLKR 909
            +  + L     +     + L  KA++       L  S+S+K    Y   ++ DLE   + 
Sbjct: 1262 QTIEGLNKLCEEQHNTISQLTLKASQLQSEIDQLKPSDSSKPKPNYSVFVKLDLEKPEQP 1321

Query: 910  ITHEHQTLIVQKKKEIEDLEIEF-------NTQIESAIRDKKVLNEKYEKNIEYVTQLEA 962
              +E + L  Q ++E ++ E E        N + E    D ++L  + ++    +++L+ 
Sbjct: 1322 NFNEEENLNEQNEEENKEEEEENKEEEENQNNEEEDDDNDNEMLMYQIQEQSREISKLKK 1381

Query: 963  QLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKD 1022
            QL + + + EN +   +       EL +++   +     D  ++    + ++   +   +
Sbjct: 1382 QLNKLEKDKENADAAFKTAMDRVHELEEENTLMKHKIDSDGVKEDKPSLEEMKGKIDLLE 1441

Query: 1023 EEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQ 1082
             E   L Q++++   + +   +D+   + +   +++  + E++++ ++L D+K   E+L+
Sbjct: 1442 YENSKLQQQVSSQPSTPVQQKNDFAENIEE---QIQQKDSEIEKLKEELADAK---EDLK 1495

Query: 1083 ILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXL 1142
              + + DD       T LT   +  K E       +E +    N ++            L
Sbjct: 1496 YALAKLDDA-----NTSLTLNSSQTKDEE---EDDLESLKSQVNELEEQRDFYIKKSENL 1547

Query: 1143 KVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQIN----Q 1198
            + ++ +E  ++ +  + Q  +  T       K   L+T+N  L       ++QI+    Q
Sbjct: 1548 E-EKVKELTRKVTNFKPQIEETKTPKSNIEDKYQNLQTVNKGLAEEISAKEKQIDLLNSQ 1606

Query: 1199 LKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHL-AQREADFQ-KTEHE 1256
            +K+K EQ+  +N++ ++ +   ++ +   + Q   E+A   ++    +RE D   K   +
Sbjct: 1607 IKNKEEQIK-QNESEINKLFVEKNDLKIKLQQSSDELAAFKRERSEVKREKDEAVKKCQD 1665

Query: 1257 LRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADV 1316
            L   L+     YEQ  D +Q   + E  K+   EQ     ++ +D  +    LQ++  ++
Sbjct: 1666 LEKVLAV---SYEQD-DKIQE-LERENQKL--NEQYLFAADQCKDSNKQRDELQKENKEL 1718

Query: 1317 INQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQ 1376
            I +I  L +++   +                     +  +QS +Q+QE       ++  Q
Sbjct: 1719 IEKINNLENDLLQAEKELDELTDEKEKLEEELSQAKKDLSQSKRQLQESK-----DDLFQ 1773

Query: 1377 LKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFEN 1436
            +KK               + D   +  +L  ++E    EI ++  E    L    ++ + 
Sbjct: 1774 IKKQMAEKERTISEQSVSIEDLGNQNDKLNEEIE----EIQKEKDENEEKLKDLQEKLKI 1829

Query: 1437 VRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESE--IERVKLIEELNVK 1494
             + +    + +   L  ++++    L   + +     E +  E++   E+V++++   +K
Sbjct: 1830 AQSKADSLKSQNNQLIKDRDNLQNQLNEFLLDGGKIDEKLVSENKQLAEKVQILQAHAIK 1889

Query: 1495 ITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKI 1554
              E  S     AE + ALE +V            Q  E+   N+E+  L  ++R+  S  
Sbjct: 1890 NIEGGSRVSAKAEEDPALERKVESLQVSLDGANKQIQELQKKNNELNELNGVLRSKLSNA 1949

Query: 1555 QK 1556
             K
Sbjct: 1950 IK 1951



 Score = 66.1 bits (154), Expect = 8e-09
 Identities = 135/656 (20%), Positives = 289/656 (44%), Gaps = 65/656 (9%)

Query: 229  EAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQEL---EQXXXXX 285
            E E K+E++   ++ E+++      +  N++L     E S E SKL ++L   E+     
Sbjct: 1334 EEENKEEEEENKEEEENQNNEEEDDDNDNEMLMYQIQEQSREISKLKKQLNKLEKDKENA 1393

Query: 286  XXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIA-NMTELTKKIELLEHLNCQIRQ-TNK 343
                        +  E +   K +I+  G  E   ++ E+  KI+LLE+ N +++Q  + 
Sbjct: 1394 DAAFKTAMDRVHELEEENTLMKHKIDSDGVKEDKPSLEEMKGKIDLLEYENSKLQQQVSS 1453

Query: 344  ELENKLATMGTESKAVSSP-SKKGSPLISRKSGRNTASK-MKSPWSQL----SSETLNQD 397
            +    +      ++ +     +K S +   K     A + +K   ++L    +S TLN  
Sbjct: 1454 QPSTPVQQKNDFAENIEEQIQQKDSEIEKLKEELADAKEDLKYALAKLDDANTSLTLNSS 1513

Query: 398  TDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQ 457
              K   ++++  L+  +  L +    +++ I + +                  Q++    
Sbjct: 1514 QTKDEEEDDLESLKSQVNELEEQ---RDFYIKKSENLEEKVKELTRKVTNFKPQIE---- 1566

Query: 458  QHMEGPSLIHVGTNTED-VNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLN 516
               + P      +N ED    +  V + L +E++ + K +++  L  ++K+ EEQI Q  
Sbjct: 1567 -ETKTPK-----SNIEDKYQNLQTVNKGLAEEISAKEKQIDL--LNSQIKNKEEQIKQNE 1618

Query: 517  DEIDAANKNMIKVKSNHKLKLKQMQKTIDNF----SKVSDSNKEIVRLTEELHHL----- 567
             EI   NK  ++ K++ K+KL+Q    +  F    S+V     E V+  ++L  +     
Sbjct: 1619 SEI---NKLFVE-KNDLKIKLQQSSDELAAFKRERSEVKREKDEAVKKCQDLEKVLAVSY 1674

Query: 568  --SQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFD 625
                K+ ELE E   L    + + + +  +S+  +  ++ EN  +  ++ I+ LE+    
Sbjct: 1675 EQDDKIQELERENQKLNEQYL-FAADQCKDSNKQRDELQKEN--KELIEKINNLENDLLQ 1731

Query: 626  LVQELHILQQKYDEVEDKLA----DISQLQSDQVCSEIKSVHLEEQIDALSASKKELALV 681
              +EL  L  + +++E++L+    D+SQ +     S+     +++Q+     +  E ++ 
Sbjct: 1732 AEKELDELTDEKEKLEEELSQAKKDLSQSKRQLQESKDDLFQIKKQMAEKERTISEQSVS 1791

Query: 682  IENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTD-KLEKMSAEKISELLAKIN 740
            IE+L    ++L   I++++ +K++   KL++ +QE + +   K + + ++    +  + N
Sbjct: 1792 IEDLGNQNDKLNEEIEEIQKEKDENEEKLKD-LQEKLKIAQSKADSLKSQNNQLIKDRDN 1850

Query: 741  HEEQ-SKIQTQFG-IDAK-IQERDLYIENIES-ELSKYK-----SRICRLEESIAVMEDR 791
             + Q ++     G ID K + E     E ++  +    K     SR+    E    +E +
Sbjct: 1851 LQNQLNEFLLDGGKIDEKLVSENKQLAEKVQILQAHAIKNIEGGSRVSAKAEEDPALERK 1910

Query: 792  RYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHE 847
              SL+   D     +QE QK  +E       L ++L+     + + EK LLE +++
Sbjct: 1911 VESLQVSLDGANKQIQELQKKNNELNELNGVLRSKLS-----NAIKEKTLLEFKND 1961


>UniRef50_A0EEL6 Cluster: Chromosome undetermined scaffold_91, whole
            genome shotgun sequence; n=2; Paramecium tetraurelia|Rep:
            Chromosome undetermined scaffold_91, whole genome shotgun
            sequence - Paramecium tetraurelia
          Length = 1894

 Score =  141 bits (342), Expect = 1e-31
 Identities = 225/1163 (19%), Positives = 500/1163 (42%), Gaps = 82/1163 (7%)

Query: 470  TNTEDVNEIAKVQEQLKQEL-NDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIK 528
            T+ +   +I ++Q + K E  N E++  N K+L ++L +  +++ Q N+ +        +
Sbjct: 453  THIKAKQQIEELQNKFKLEFQNYELQLKNYKELYDQLSNTNKELVQKNENLQVEFNRQTQ 512

Query: 529  VKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEEL----HHLSQKVAELEEEKGNLQLH 584
            +       L+  Q+ I N ++ +   KE +  ++EL    +    ++ + ++E   L   
Sbjct: 513  ISVT---ALQNKQQEILNLNEQTKKLKEDITKSQELKLTYNEQQTQINQFKKEIERLNQV 569

Query: 585  LVDYDSGRMIESDVYKKMIEMENLAETRLKAISL-LESQKFDLVQELHILQQKYDEVEDK 643
            ++   S    + +    +IE      TRL  + + L SQ      ++ +L++    ++DK
Sbjct: 570  ILQNQSKSSQQEENLLTVIEQNKSEITRLHQLIIDLHSQIEQSDNQIQLLKEAEQIIKDK 629

Query: 644  LADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKL--DKEQLYGTIKDLEN 701
            +   S + SD+V  +++ +   ++I+  +  ++  A+  +N++    ++Q   TIK ++ 
Sbjct: 630  ITKDSLVYSDKV-KKLQEIIQNKEIEHSALEEEYKAIQSQNVEFYSQQQQDQDTIKLMKK 688

Query: 702  DKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERD 761
            D    + K Q   ++ ++   KL +    +I +L  K    E  + + Q     K+++  
Sbjct: 689  D----LQKNQEQYEQKINEFIKLSERQLAEIKDLSEKYQQAENER-RNQDETITKLKKE- 742

Query: 762  LYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAY--SEYTIQ 819
              ++       + K+   + ++S  +++ +  S ER  +Q    + E++K    S+  +Q
Sbjct: 743  -LLKQTNDHQKQVKTLQDQQKQSQEMLQQKLQSFERLNEQNQMIICEQKKLLHESQAQLQ 801

Query: 820  EDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEEN---QNLQISLSDMQQH- 875
            +  L N  A+L ++   ++    + E    EL +  Q++L++    QN Q+   D QQ  
Sbjct: 802  KVNLENE-ALLQNNSESMQSMKEQYELLALELNQTKQVVLDQQELIQNQQLLHHDTQQEC 860

Query: 876  --------YNALVEKANRTDLAES--ESTKYQTQLR-DLESNLKR-----ITHEH--QTL 917
                       +V K N+++L ++  +      QL+ +LE+  KR     IT E   QTL
Sbjct: 861  YKFKKQIEQQDIVNKQNQSELGKTIQDQINLINQLKSNLEATEKRHIENKITAEQLSQTL 920

Query: 918  IVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQL-EAQLQEYKNNIENL-N 975
            I  +  EI  L  E +TQ+ + I       +  +  ++   Q  E +L++ + N++ + N
Sbjct: 921  ITTQS-EITQLRFE-STQLNNTIEQNSKTIQDLQSQLQIDQQQHEIELKQIQKNLDLVQN 978

Query: 976  MNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEI-IALNQKINN 1034
             + +E   + LEL  K +Q+ Q Q  +  +QY +++ +    +K   E   + L Q+IN 
Sbjct: 979  QSNQEKESIILEL-HKQIQEFQEQLQNQRDQYQHDVQQHQIQIKLNQERFDLVLQQEINQ 1037

Query: 1035 AQVSYMSMVSDYESKLAQFTTK---LENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQ 1091
                    +S  E +   F  +   LEN   ++ + +K++    Q N+ L   + EQ + 
Sbjct: 1038 INCQMEQQISTKEEEKQGFLDQIKALENKIVQLDQKNKEIYLQSQSNQNLYRQLIEQLET 1097

Query: 1092 IK-ELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEF 1150
            ++ E +  +L ++  + + +  I +  I   S+    ++            ++ Q++ + 
Sbjct: 1098 LQQESQNEQLKWKDLLQQKDEKIRTIEINSKSE-IGKLNEQLIHTSERRAQIE-QDQIKL 1155

Query: 1151 IQERSVLQEQSAKLNTELQECYTKIIQLETL-NTELTGHDVVNQEQINQLKSKLEQLNTE 1209
            I++  +  ++  KL  +L++   +I  ++ L N  +  ++ +N + I  +  ++     +
Sbjct: 1156 IEQEQITNQELQKLKEQLEQKQNEIDSIDKLLNERVLDNEELNGKLI-LVSKEMSLYKDQ 1214

Query: 1210 NDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYE 1269
            N +L S +++   S S+ +++  F+I          +E DF    ++L+ Q+  FE +  
Sbjct: 1215 NKDLQSQISQQSESNSNTINELKFKI----------KEQDF--LINQLQSQVKDFECQMN 1262

Query: 1270 QLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIED 1329
              L  V   +++  NK    +++    N+L   +     LQ +  D++ QI IL+ EI +
Sbjct: 1263 LQLSEVILQSKDLVNK--KQQELDISSNELTQLKNQFIKLQNENDDLLKQITILQ-EINN 1319

Query: 1330 EKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNI-NEENAQLKKSSXXXXXXX 1388
             K                    +   NQ  KQ +  ++LN+      Q+   +       
Sbjct: 1320 NKDIQINDFENQVTKLHEQVNTINNYNQ-LKQEELDNVLNLLKNREQQIADQNELINNLQ 1378

Query: 1389 XXXXXRVNDAEAKVLELTH---QLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYE 1445
                 +  D   K+  L     Q   + SE+ Q   +  +   +  +E     + L E  
Sbjct: 1379 ILQVKQEQDYNEKLNNLNQVSMQSSSEQSELKQIVEQVQMEKEKITEELLKKNENLKEIV 1438

Query: 1446 KRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQV 1505
            K  +    +   +L+    ++ E     E  Q +S++  ++L EEL + + E    N ++
Sbjct: 1439 KNQQTTCQQLNEQLSSKDTELQEQGILIE--QYQSQV--LQLNEELTLIMDEKSQQNLKI 1494

Query: 1506 AELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTK 1565
             +L   +E+           L+N ++E      +  +  N +   + ++   +S   +  
Sbjct: 1495 HQLRTNIEKIQQDLEVKSIQLQNSDLESENQKQQFESQLNELGNQNKELFVRLSELQEEN 1554

Query: 1566 QGRDEQLDNTMNKELLDAVPRAE 1588
                EQ+    N+  L      E
Sbjct: 1555 STLIEQVRKRENEYRLKVFEMGE 1577



 Score =  135 bits (326), Expect = 1e-29
 Identities = 282/1444 (19%), Positives = 604/1444 (41%), Gaps = 120/1444 (8%)

Query: 92   ESLANTLKQKEILME-KIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSN- 149
            E L N  K +    E ++K YKEL  + S T                      VT L N 
Sbjct: 462  EELQNKFKLEFQNYELQLKNYKELYDQLSNTNKELVQKNENLQVEFNRQTQISVTALQNK 521

Query: 150  -----TIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXX 204
                  + E+   L     K + ++ T  + Q +IN+  + IE  N+             
Sbjct: 522  QQEILNLNEQTKKLKEDITKSQELKLTYNEQQTQINQFKKEIERLNQVILQNQSKSSQQE 581

Query: 205  XXXXXXXEDTKQQMTKMQENFIAMEA--EWKDEKQRLLKDIES--KD-VRISSLEEANKL 259
                   E  K ++T++ +  I + +  E  D + +LLK+ E   KD +   SL  ++K+
Sbjct: 582  ENLLTVIEQNKSEITRLHQLIIDLHSQIEQSDNQIQLLKEAEQIIKDKITKDSLVYSDKV 641

Query: 260  --LEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLE 317
              L+       +EHS L +E +                 + +I+   ++  + +E+   +
Sbjct: 642  KKLQEIIQNKEIEHSALEEEYKAIQSQNVEFYSQQQQ-DQDTIKLMKKDLQKNQEQYEQK 700

Query: 318  IANMTELTKK-IELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGR 376
            I    +L+++ +  ++ L+ + +Q   E  N+  T+    K +   +      +     +
Sbjct: 701  INEFIKLSERQLAEIKDLSEKYQQAENERRNQDETITKLKKELLKQTNDHQKQVKTLQDQ 760

Query: 377  NTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVI---SEKDT 433
               S+        S E LN+     I + +    E   Q L K  ++ E ++   SE   
Sbjct: 761  QKQSQEMLQQKLQSFERLNEQNQMIICEQKKLLHESQAQ-LQKVNLENEALLQNNSESMQ 819

Query: 434  XXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEI 493
                       +     Q+ L+ Q+ ++   L+H  T      E  K ++Q++Q+  D +
Sbjct: 820  SMKEQYELLALELNQTKQVVLDQQELIQNQQLLHHDTQ----QECYKFKKQIEQQ--DIV 873

Query: 494  KDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKT-IDNFSKVSD 552
               N  +L + ++     I QL   ++A  K  I+    +K+  +Q+ +T I   S+++ 
Sbjct: 874  NKQNQSELGKTIQDQINLINQLKSNLEATEKRHIE----NKITAEQLSQTLITTQSEITQ 929

Query: 553  SNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETR 612
               E  +L   +   S+ + +L+ +   LQ   +D     +    + K +  ++N +   
Sbjct: 930  LRFESTQLNNTIEQNSKTIQDLQSQ---LQ---IDQQQHEIELKQIQKNLDLVQNQSNQE 983

Query: 613  LKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSD-QVCSEIKSVHLEEQIDAL 671
             ++I L   ++    QE   LQ + D+ +    D+ Q Q   ++  E   + L+++I+ +
Sbjct: 984  KESIILELHKQIQEFQEQ--LQNQRDQYQH---DVQQHQIQIKLNQERFDLVLQQEINQI 1038

Query: 672  SASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEK 731
            +   ++    I   + +K+     IK LEN       K+    Q+N ++   L+  S + 
Sbjct: 1039 NCQMEQQ---ISTKEEEKQGFLDQIKALEN-------KIVQLDQKNKEIY--LQSQSNQN 1086

Query: 732  I-SELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMED 790
            +  +L+ ++   +Q     Q      +Q++D  I  IE      KS I +L E +    +
Sbjct: 1087 LYRQLIEQLETLQQESQNEQLKWKDLLQQKDEKIRTIEINS---KSEIGKLNEQLIHTSE 1143

Query: 791  RRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKE 850
            RR  +E+  DQ+   ++++Q    E    +++L  +   +   D+++ +++L+ E  N +
Sbjct: 1144 RRAQIEQ--DQI-KLIEQEQITNQELQKLKEQLEQKQNEIDSIDKLLNERVLDNEELNGK 1200

Query: 851  L---QKKNQILLEENQNLQISLSDMQQ-HYNALVEKANRTDLAESESTKYQTQLRDLESN 906
            L    K+  +  ++N++LQ  +S   + + N + E   +    +    + Q+Q++D E  
Sbjct: 1201 LILVSKEMSLYKDQNKDLQSQISQQSESNSNTINELKFKIKEQDFLINQLQSQVKDFECQ 1260

Query: 907  LKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQE 966
            +     E   +I+Q K  +   + E +       + K    +   +N + + Q+   LQE
Sbjct: 1261 MNLQLSE---VILQSKDLVNKKQQELDISSNELTQLKNQFIKLQNENDDLLKQITI-LQE 1316

Query: 967  YKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEII 1026
              NN +       ++N    ++   H Q     + +  +Q   E++ +  LLK ++++I 
Sbjct: 1317 INNNKDI------QINDFENQVTKLHEQVNTINNYNQLKQ--EELDNVLNLLKNREQQIA 1368

Query: 1027 ALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVR 1086
              N+ INN Q+  +    DY         KL N+ +   + S +  + KQ  E++Q+   
Sbjct: 1369 DQNELINNLQILQVKQEQDYNE-------KLNNLNQVSMQSSSEQSELKQIVEQVQM--- 1418

Query: 1087 EQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSD-DANNVDXXXXXXXXXXXXLKVQ 1145
            E++   +EL +     +  I K +        E +S  D    +            L++ 
Sbjct: 1419 EKEKITEELLKKNENLK-EIVKNQQTTCQQLNEQLSSKDTELQEQGILIEQYQSQVLQLN 1477

Query: 1146 EEEEFIQERSVLQEQSAKLNTELQECYTKIIQ-LETLNTELTGHDVVNQEQINQLKSKLE 1204
            EE   I +     +Q+ K++ +L+    KI Q LE  + +L   D+ ++ Q  Q +S+L 
Sbjct: 1478 EELTLIMDEK--SQQNLKIH-QLRTNIEKIQQDLEVKSIQLQNSDLESENQKQQFESQLN 1534

Query: 1205 QLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAF 1264
            +L  +N  L   ++EL+   S+ ++Q            + +RE +++    E+  + + F
Sbjct: 1535 ELGNQNKELFVRLSELQEENSTLIEQ------------VRKRENEYRLKVFEMG-EKNRF 1581

Query: 1265 ESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQI-EIL 1323
            E++ +  ++ +    QE +   V+ E V +  ++++++ + L + Q +Y+ +I Q+   L
Sbjct: 1582 ENEEQNKINQILQ--QELSISEVSEENVINALSQIKNEFQELLDKQSQYSTLIFQLYSEL 1639

Query: 1324 RSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINE--ENAQLKKSS 1381
             ++ E+E V                  D   + ++  + +   ++ I E   + Q K+SS
Sbjct: 1640 LTDDEEEDVEKQIQVISNQMVGLIDVRDKYKKIENEFEGEGDILVKIKELKLSEQKKQSS 1699

Query: 1382 XXXXXXXXXXXXRVNDA---EAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVR 1438
                        ++ D    E     +   ++   S + ++  +      ++  E +N  
Sbjct: 1700 NSQDIKSIEAYSQLLDGLMQEFLHNRVNLTMQSMKSLLTEQQRQNVNEYRKKIGELQNKL 1759

Query: 1439 QQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITES 1498
             Q  + +K I+D  +  +    I+  K  + A +YE   K    + V+ I+E+  ++ + 
Sbjct: 1760 LQAEKQQKCIDDTKFNLQQYQQIVD-KSEQKAMYYEMECK----KLVQQIQEMKQRMPQR 1814

Query: 1499 VSLN 1502
            +SLN
Sbjct: 1815 ISLN 1818



 Score =  128 bits (309), Expect = 1e-27
 Identities = 232/1195 (19%), Positives = 489/1195 (40%), Gaps = 94/1195 (7%)

Query: 446  DTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQL-KQELNDEIKDVNVKDLIEK 504
            D+L  QL+   Q++      +    N++ ++ +A+++ QL K E   E + V +K L + 
Sbjct: 136  DSLAVQLEKIKQENDTLRKRVSDNINSQSLSNLAQLKMQLQKAEKKAESRKVCIKKLYQL 195

Query: 505  LKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEEL 564
            L  +E+++     E+  + K   K   + K +L ++       +     NKE +  T E 
Sbjct: 196  LDKSEKEL-----ELYKSGKKSAKTSFSKKNELNEI------LNGTYPKNKENIPDTYEP 244

Query: 565  HHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKF 624
              LS  + +++++  N +  + +      + +DV     E  NL    LK+  L+  QK 
Sbjct: 245  MLLSL-IKDIDQK--NYEA-IENLSKNNSLNTDVEN---EKNNLISNSLKSFKLMCEQKE 297

Query: 625  DLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSV-HLEEQIDALSASKKELALVIE 683
            ++++    + +   ++  K  +I      Q+ +  +++  LE  I +      ++     
Sbjct: 298  EILKYSAQICENNQDLWKKFLEIDLTCQKQISTLRQAISELETNIKSYYQYLNKIGHNSA 357

Query: 684  NLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEE 743
                D  Q  G I D        + ++Q  I +      + ++     +  L   I + +
Sbjct: 358  QKFQDAYQFQGVIGDSIAKWLKQLGEIQEIINQRESEQYEFQQFQETLVMRLKEIIQNNK 417

Query: 744  QSKIQTQF-GIDAKIQERDLYIENIESELSKYKSRICRLEESIAVME-DRRYSLERKADQ 801
                Q  F G+   I ER L+ ++ E  L   +     ++    + E   ++ LE +  +
Sbjct: 418  IVHKQNDFKGLLDAINER-LFNQSEEILLINKELNNTHIKAKQQIEELQNKFKLEFQNYE 476

Query: 802  LGSYLQEKQKAYSEYTIQEDELVNRLAVL-MDHDRVVEKQLLEIEHENKELQKKNQIL-- 858
            L   L+  ++ Y + +    ELV +   L ++ +R  +  +  ++++ +E+   N+    
Sbjct: 477  L--QLKNYKELYDQLSNTNKELVQKNENLQVEFNRQTQISVTALQNKQQEILNLNEQTKK 534

Query: 859  ----LEENQNLQISLSDMQQHYNAL---VEKANRTDLAESESTKYQTQ--LRDLESNLKR 909
                + ++Q L+++ ++ Q   N     +E+ N+  L     +  Q +  L  +E N   
Sbjct: 535  LKEDITKSQELKLTYNEQQTQINQFKKEIERLNQVILQNQSKSSQQEENLLTVIEQNKSE 594

Query: 910  ITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKN 969
            IT  HQ LI+    +IE    + + QI+     ++++ +K  K+    +    +LQE   
Sbjct: 595  ITRLHQ-LIIDLHSQIE----QSDNQIQLLKEAEQIIKDKITKDSLVYSDKVKKLQEIIQ 649

Query: 970  NIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALN 1029
            N E  +  +EE  K  ++  +     QQ Q  D  +    ++ K     +QK  E I L+
Sbjct: 650  NKEIEHSALEEEYKA-IQSQNVEFYSQQQQDQDTIKLMKKDLQKNQEQYEQKINEFIKLS 708

Query: 1030 QKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLL-DSKQHNEELQILVREQ 1088
            ++        ++ + D   K  Q   +  N +E + ++ K+LL  +  H ++++ L ++Q
Sbjct: 709  ER-------QLAEIKDLSEKYQQAENERRNQDETITKLKKELLKQTNDHQKQVKTL-QDQ 760

Query: 1089 DDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEE 1148
              Q +E+ + KL     + +   MII    + + +    +               +Q   
Sbjct: 761  QKQSQEMLQQKLQSFERLNEQNQMIICEQKKLLHESQAQLQKVNLENEAL-----LQNNS 815

Query: 1149 EFIQERSVLQEQSAKLNTELQECYTKIIQLETL--NTELTGHDVVNQEQINQLKSKLEQL 1206
            E +Q    ++EQ   L  EL +    ++  + L  N +L  HD   Q++  + K ++EQ 
Sbjct: 816  ESMQS---MKEQYELLALELNQTKQVVLDQQELIQNQQLLHHDT--QQECYKFKKQIEQQ 870

Query: 1207 NTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFES 1266
            +  N    S + +      + ++Q    +    K+H+  +      T  +L   L   +S
Sbjct: 871  DIVNKQNQSELGKTIQDQINLINQLKSNLEATEKRHIENKI-----TAEQLSQTLITTQS 925

Query: 1267 KYEQL-LDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRS 1325
            +  QL  +S Q +   E N     +  + LQ   Q  E  L+ +Q+    V NQ    + 
Sbjct: 926  EITQLRFESTQLNNTIEQNSKTIQDLQSQLQIDQQQHEIELKQIQKNLDLVQNQSNQEKE 985

Query: 1326 EIEDE-KVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSIL----NINEENAQLKKS 1380
             I  E                     D++      K  QE+  L     IN+ N Q+++ 
Sbjct: 986  SIILELHKQIQEFQEQLQNQRDQYQHDVQQHQIQIKLNQERFDLVLQQEINQINCQMEQQ 1045

Query: 1381 SXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQ 1440
                         ++   E K++    QL+ K+ EIY ++        Q  ++ E ++Q+
Sbjct: 1046 ISTKEEEKQGFLDQIKALENKIV----QLDQKNKEIYLQSQSNQNLYRQLIEQLETLQQE 1101

Query: 1441 LVEYEKRIEDLTYEKESELAILRL-------KMHENANHYETMQKESEIERVKLIEELNV 1493
                + + +DL  +K+ ++  + +       K++E   H    + + E +++KLIE+  +
Sbjct: 1102 SQNEQLKWKDLLQQKDEKIRTIEINSKSEIGKLNEQLIHTSERRAQIEQDQIKLIEQEQI 1161

Query: 1494 KITESVSLNKQVAE-------LNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNM 1546
               E   L +Q+ +       ++K L E V    E+   L     E+    D+  +LQ+ 
Sbjct: 1162 TNQELQKLKEQLEQKQNEIDSIDKLLNERVLDNEELNGKLILVSKEMSLYKDQNKDLQSQ 1221

Query: 1547 VRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDLAMYMLHQRDV 1601
            +   S      ++     K    + L N +  ++ D   +  L L+  +L  +D+
Sbjct: 1222 ISQQSESNSNTIN-ELKFKIKEQDFLINQLQSQVKDFECQMNLQLSEVILQSKDL 1275



 Score =  128 bits (309), Expect = 1e-27
 Identities = 239/1164 (20%), Positives = 527/1164 (45%), Gaps = 139/1164 (11%)

Query: 498  VKDLIEKLKSAEEQITQ---LNDEIDAANKNMIKVK-SNHKLKLKQMQKTIDNFSKVSDS 553
            +KD+ +K   A E +++   LN +++    N+I     + KL  +Q ++ +   +++ ++
Sbjct: 250  IKDIDQKNYEAIENLSKNNSLNTDVENEKNNLISNSLKSFKLMCEQKEEILKYSAQICEN 309

Query: 554  NKEI------VRLT--EELHHLSQKVAELEEE-KGNLQ-LHLVDYDSGRMIESDVYKKMI 603
            N+++      + LT  +++  L Q ++ELE   K   Q L+ + ++S +  + D Y+   
Sbjct: 310  NQDLWKKFLEIDLTCQKQISTLRQAISELETNIKSYYQYLNKIGHNSAQKFQ-DAYQFQG 368

Query: 604  EMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVH 663
             + +     LK +  ++    +++ +    Q ++ + ++ L     ++  ++    K VH
Sbjct: 369  VIGDSIAKWLKQLGEIQ----EIINQRESEQYEFQQFQETLV----MRLKEIIQNNKIVH 420

Query: 664  LEEQIDAL-SASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTD 722
             +     L  A  + L    E + L  ++L  T    +   E++ NK +   Q N +L  
Sbjct: 421  KQNDFKGLLDAINERLFNQSEEILLINKELNNTHIKAKQQIEELQNKFKLEFQ-NYELQL 479

Query: 723  KLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLE 782
            K  K   +++S    ++  + ++ +Q +F    +I    L  +N + E+     +  +L+
Sbjct: 480  KNYKELYDQLSNTNKELVQKNEN-LQVEFNRQTQISVTAL--QNKQQEILNLNEQTKKLK 536

Query: 783  ESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLL 842
            E I   ++ + +   +  Q+  + +E ++  ++  +Q     ++           E+ LL
Sbjct: 537  EDITKSQELKLTYNEQQTQINQFKKEIERL-NQVILQNQSKSSQQ----------EENLL 585

Query: 843  EIEHENK-ELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLR 901
             +  +NK E+ + +Q++++ +   QI  SD Q       E+  + D    +S  Y  +++
Sbjct: 586  TVIEQNKSEITRLHQLIIDLHS--QIEQSDNQIQLLKEAEQIIK-DKITKDSLVYSDKVK 642

Query: 902  DLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQ-------IESAIRDKKVLNEKYEKNI 954
             L+  ++    EH  L  ++ K I+   +EF +Q       I+   +D +   E+YE+ I
Sbjct: 643  KLQEIIQNKEIEHSAL-EEEYKAIQSQNVEFYSQQQQDQDTIKLMKKDLQKNQEQYEQKI 701

Query: 955  -EYVTQLEAQLQEYKN------NIENLNMNVEE-LNKMNLELID---------KHVQKQQ 997
             E++   E QL E K+        EN   N +E + K+  EL+          K +Q QQ
Sbjct: 702  NEFIKLSERQLAEIKDLSEKYQQAENERRNQDETITKLKKELLKQTNDHQKQVKTLQDQQ 761

Query: 998  TQSPDYTEQYINEINKLNALLKQKDEEIIALNQKI-NNAQVSYMSMVSDYESKLAQFTTK 1056
             QS +  +Q +    +LN    ++++ II   +K+ + +Q     +  + E+ L   +  
Sbjct: 762  KQSQEMLQQKLQSFERLN----EQNQMIICEQKKLLHESQAQLQKVNLENEALLQNNSES 817

Query: 1057 LENMEEEMQRVSKQLLDSKQHNEELQILVREQD----DQIKELKETKLTFEMN--IPKTE 1110
            +++M+E+ + ++ +L  +KQ   + Q L++ Q     D  +E  + K   E    + K  
Sbjct: 818  MQSMKEQYELLALELNQTKQVVLDQQELIQNQQLLHHDTQQECYKFKKQIEQQDIVNKQN 877

Query: 1111 GMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQE 1170
               +  TI+   +  N +              K+  E+   Q     Q +  +L  E  +
Sbjct: 878  QSELGKTIQDQINLINQLKSNLEATEKRHIENKITAEQ-LSQTLITTQSEITQLRFESTQ 936

Query: 1171 CYTKIIQLETLNTELTGHDVVNQEQINQLKSKLE--QLNTENDNLLSTVAELRSSISSAV 1228
                I Q    N++ T  D+ +Q QI+Q + ++E  Q+    D + +   + + SI   +
Sbjct: 937  LNNTIEQ----NSK-TIQDLQSQLQIDQQQHEIELKQIQKNLDLVQNQSNQEKESIILEL 991

Query: 1229 DQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSV------QSSTQEE 1282
             ++  E  E  +    Q + D Q+ + ++++    F+   +Q ++ +      Q ST+EE
Sbjct: 992  HKQIQEFQEQLQNQRDQYQHDVQQHQIQIKLNQERFDLVLQQEINQINCQMEQQISTKEE 1051

Query: 1283 TNKIVTMEQVTSLQNKL-----QDKEEHLRNL--QEKYADVINQIEILRSEIEDEKVAFX 1335
              K   ++Q+ +L+NK+     ++KE +L++   Q  Y  +I Q+E L+ E ++E++ + 
Sbjct: 1052 -EKQGFLDQIKALENKIVQLDQKNKEIYLQSQSNQNLYRQLIEQLETLQQESQNEQLKWK 1110

Query: 1336 XXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRV 1395
                           + ++E     ++ EQ +++ +E  AQ+++              ++
Sbjct: 1111 DLLQQKDEKIRTIEINSKSE---IGKLNEQ-LIHTSERRAQIEQDQIKLIEQE-----QI 1161

Query: 1396 NDAEAKVLELTHQLELKDSEIY---QKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLT 1452
             + E +  +L  QLE K +EI    +  +E  +   + N +   V +++  Y+ + +DL 
Sbjct: 1162 TNQELQ--KLKEQLEQKQNEIDSIDKLLNERVLDNEELNGKLILVSKEMSLYKDQNKDLQ 1219

Query: 1453 YE--KESEL---AILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAE 1507
             +  ++SE     I  LK       +   Q +S+++  +   ++N++++E +  +K +  
Sbjct: 1220 SQISQQSESNSNTINELKFKIKEQDFLINQLQSQVKDFEC--QMNLQLSEVILQSKDL-- 1275

Query: 1508 LNKALEEEVAKTNEMQTALENQEIEIVTLNDE----ITNLQ----------NMVRASSSK 1553
            +NK  +E    +NE+ T L+NQ I++   ND+    IT LQ          N      +K
Sbjct: 1276 VNKKQQELDISSNEL-TQLKNQFIKLQNENDDLLKQITILQEINNNKDIQINDFENQVTK 1334

Query: 1554 IQKHVSFASDTKQGRDEQLDNTMN 1577
            + + V+  ++  Q + E+LDN +N
Sbjct: 1335 LHEQVNTINNYNQLKQEELDNVLN 1358



 Score =  127 bits (307), Expect = 2e-27
 Identities = 237/1248 (18%), Positives = 538/1248 (43%), Gaps = 94/1248 (7%)

Query: 369  LISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDK-EYV 427
            L+  K   NT  K K    +L ++   +  + ++      +L   + + NK+LV K E +
Sbjct: 444  LLINKELNNTHIKAKQQIEELQNKFKLEFQNYELQLKNYKELYDQLSNTNKELVQKNENL 503

Query: 428  ISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSL-----IHVGTNTEDVNEIAKVQ 482
              E +            K   I  L  + ++  E  +      +        +N+  K  
Sbjct: 504  QVEFNRQTQISVTALQNKQQEILNLNEQTKKLKEDITKSQELKLTYNEQQTQINQFKKEI 563

Query: 483  EQLKQEL--NDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQM 540
            E+L Q +  N        ++L+  ++  + +IT+L+  I   + + I+   N    LK+ 
Sbjct: 564  ERLNQVILQNQSKSSQQEENLLTVIEQNKSEITRLHQLIIDLH-SQIEQSDNQIQLLKEA 622

Query: 541  QKTI-DNFSKVS-DSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDV 598
            ++ I D  +K S   + ++ +L E + +   + + LEEE   +Q   V++ S +  + D 
Sbjct: 623  EQIIKDKITKDSLVYSDKVKKLQEIIQNKEIEHSALEEEYKAIQSQNVEFYSQQQQDQDT 682

Query: 599  YKKMIE--MENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVC 656
             K M +   +N  +   K    ++  +  L  E+  L +KY + E++  +  +  +    
Sbjct: 683  IKLMKKDLQKNQEQYEQKINEFIKLSERQLA-EIKDLSEKYQQAENERRNQDETITKLKK 741

Query: 657  SEIKSVH-LEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQ 715
              +K  +  ++Q+  L   +K+   +++      E+L    + +  +++ ++++ Q  +Q
Sbjct: 742  ELLKQTNDHQKQVKTLQDQQKQSQEMLQQKLQSFERLNEQNQMIICEQKKLLHESQAQLQ 801

Query: 716  E-NMD----LTDKLEKMSAEKIS-ELLA-KINHEEQSKIQTQFGIDAKIQERDLYIENIE 768
            + N++    L +  E M + K   ELLA ++N  +Q  +  Q      IQ + L   + +
Sbjct: 802  KVNLENEALLQNNSESMQSMKEQYELLALELNQTKQVVLDQQ----ELIQNQQLLHHDTQ 857

Query: 769  SELSKYKSRICRLEESIAVMEDRRYSLERKA-------DQLGSYLQEKQKAYSEYTIQED 821
             E  K+K +I   E+   V +  +  L +         +QL S L+  +K + E  I  +
Sbjct: 858  QECYKFKKQI---EQQDIVNKQNQSELGKTIQDQINLINQLKSNLEATEKRHIENKITAE 914

Query: 822  ELVNRLAVLMDHD---RVVEKQLLE-IEHENKELQKKNQILLEENQNLQISLSDMQQHYN 877
            +L   L          R    QL   IE  +K +Q     L  + Q  +I L  +Q++ +
Sbjct: 915  QLSQTLITTQSEITQLRFESTQLNNTIEQNSKTIQDLQSQLQIDQQQHEIELKQIQKNLD 974

Query: 878  ALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIE 937
             +  ++N+    ES   +   Q+++ +  L+    ++Q  + Q + +I+  +  F+  ++
Sbjct: 975  LVQNQSNQEK--ESIILELHKQIQEFQEQLQNQRDQYQHDVQQHQIQIKLNQERFDLVLQ 1032

Query: 938  SAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELI-----DKH 992
              I     +N + E+ I   +  E + Q + + I+ L   + +L++ N E+      +++
Sbjct: 1033 QEINQ---INCQMEQQI---STKEEEKQGFLDQIKALENKIVQLDQKNKEIYLQSQSNQN 1086

Query: 993  VQKQQTQSPDYTEQYI-NEINKLNALLKQKDEEI--IALNQKINNAQVSYMSM-VSDYES 1048
            + +Q  +  +  +Q   NE  K   LL+QKDE+I  I +N K    +++   +  S+  +
Sbjct: 1087 LYRQLIEQLETLQQESQNEQLKWKDLLQQKDEKIRTIEINSKSEIGKLNEQLIHTSERRA 1146

Query: 1049 KLAQFTTKLENMEE----EMQRVSKQLLDSKQHNEELQILVREQDDQIKEL--KETKLTF 1102
            ++ Q   KL   E+    E+Q++ +QL   +   + +  L+ E+    +EL  K   ++ 
Sbjct: 1147 QIEQDQIKLIEQEQITNQELQKLKEQLEQKQNEIDSIDKLLNERVLDNEELNGKLILVSK 1206

Query: 1103 EMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQE-RSVLQEQS 1161
            EM++ K +   + S I   S+  +N               K++E++  I + +S +++  
Sbjct: 1207 EMSLYKDQNKDLQSQISQQSESNSNT--------INELKFKIKEQDFLINQLQSQVKDFE 1258

Query: 1162 AKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVA--- 1218
             ++N +L E    I+Q + L  +      ++  ++ QLK++  +L  END+LL  +    
Sbjct: 1259 CQMNLQLSEV---ILQSKDLVNKKQQELDISSNELTQLKNQFIKLQNENDDLLKQITILQ 1315

Query: 1219 ELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSS 1278
            E+ ++    ++    ++ +L +Q       +  K E EL   L+  +++ +Q+ D  +  
Sbjct: 1316 EINNNKDIQINDFENQVTKLHEQVNTINNYNQLKQE-ELDNVLNLLKNREQQIADQNELI 1374

Query: 1279 TQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXX 1338
               +  ++   +      N L        + Q +   ++ Q+++ + +I +E +      
Sbjct: 1375 NNLQILQVKQEQDYNEKLNNLNQVSMQSSSEQSELKQIVEQVQMEKEKITEELLKKNENL 1434

Query: 1339 XXXXXXXXXXXXDLRTENQSYK-QMQEQSIL--NINEENAQLKKSSXXXXXXXXXXXXRV 1395
                         L  +  S   ++QEQ IL      +  QL +              ++
Sbjct: 1435 KEIVKNQQTTCQQLNEQLSSKDTELQEQGILIEQYQSQVLQLNEELTLIMDEKSQQNLKI 1494

Query: 1396 NDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEK 1455
            +     + ++   LE+K  ++     E      Q   +   +  Q  E   R+ +L  E 
Sbjct: 1495 HQLRTNIEKIQQDLEVKSIQLQNSDLESENQKQQFESQLNELGNQNKELFVRLSELQEEN 1554

Query: 1456 ESELAILR-------LKMHE--NANHYETMQKESEIERVKLIEELNVKITESVSLNKQVA 1506
             + +  +R       LK+ E    N +E  +++++I ++ L +EL++      ++   ++
Sbjct: 1555 STLIEQVRKRENEYRLKVFEMGEKNRFEN-EEQNKINQI-LQQELSISEVSEENVINALS 1612

Query: 1507 ELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKI 1554
            ++    +E + K ++  T +     E++T +DE  +++  ++  S+++
Sbjct: 1613 QIKNEFQELLDKQSQYSTLIFQLYSELLT-DDEEEDVEKQIQVISNQM 1659



 Score =  117 bits (281), Expect = 3e-24
 Identities = 213/1147 (18%), Positives = 485/1147 (42%), Gaps = 101/1147 (8%)

Query: 500  DLIEKLKSAEEQITQLNDEIDAANKNMI-KVKSNHKLKLKQMQKTIDNFSKVSDSNKEIV 558
            D++E   S   Q+ ++  E D   K +   + S     L Q++  +    K ++S K  +
Sbjct: 130  DVLESADSLAVQLEKIKQENDTLRKRVSDNINSQSLSNLAQLKMQLQKAEKKAESRKVCI 189

Query: 559  RLTEELHHLSQKVAELEEE-KGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETR----L 613
            +   +L   S+K  EL +  K + +      +    I +  Y K    EN+ +T     L
Sbjct: 190  KKLYQLLDKSEKELELYKSGKKSAKTSFSKKNELNEILNGTYPK--NKENIPDTYEPMLL 247

Query: 614  KAISLLESQKFDLVQELHILQQKYDEVEDKLADI--SQLQSDQVCSEIKSVHLEEQIDAL 671
              I  ++ + ++ ++ L        +VE++  ++  + L+S ++  E K   L+      
Sbjct: 248  SLIKDIDQKNYEAIENLSKNNSLNTDVENEKNNLISNSLKSFKLMCEQKEEILKYSAQIC 307

Query: 672  SASKKELALVIE-NLKLDKE--QLYGTIKDLENDKEDI---MNKLQNYIQENMDLTDKLE 725
              ++      +E +L   K+   L   I +LE + +     +NK+ +   +      + +
Sbjct: 308  ENNQDLWKKFLEIDLTCQKQISTLRQAISELETNIKSYYQYLNKIGHNSAQKFQDAYQFQ 367

Query: 726  KMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESI 785
             +  + I++ L ++  E Q  I  +     + Q+    +     E+ +    + +  +  
Sbjct: 368  GVIGDSIAKWLKQLG-EIQEIINQRESEQYEFQQFQETLVMRLKEIIQNNKIVHKQNDFK 426

Query: 786  AVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIE 845
             +++     L  +++++    +E    + +   Q +EL N+  +   +    E QL   +
Sbjct: 427  GLLDAINERLFNQSEEILLINKELNNTHIKAKQQIEELQNKFKLEFQN---YELQLKNYK 483

Query: 846  HENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLES 905
                +L   N+ L+++N+NLQ+  +   Q     ++   +  L  +E TK   +      
Sbjct: 484  ELYDQLSNTNKELVQKNENLQVEFNRQTQISVTALQNKQQEILNLNEQTKKLKEDITKSQ 543

Query: 906  NLKRITHEHQTLIVQKKKEIEDL-EIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQL 964
             LK   +E QT I Q KKEIE L ++    Q +S+ +++ +L    E+N   +T+L   +
Sbjct: 544  ELKLTYNEQQTQINQFKKEIERLNQVILQNQSKSSQQEENLLT-VIEQNKSEITRLHQLI 602

Query: 965  QEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEE 1024
             +  + IE  +  ++ L +   ++I   + K           Y +++ KL  +++ K+ E
Sbjct: 603  IDLHSQIEQSDNQIQLLKEAE-QIIKDKITKDSL-------VYSDKVKKLQEIIQNKEIE 654

Query: 1025 IIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQIL 1084
              AL ++    Q   +   S  +    Q T KL  M++++Q+      + +Q+ +++   
Sbjct: 655  HSALEEEYKAIQSQNVEFYSQQQQD--QDTIKL--MKKDLQK------NQEQYEQKINEF 704

Query: 1085 VREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKV 1144
            ++  + Q+ E+K+                +S   +   ++  N D              +
Sbjct: 705  IKLSERQLAEIKD----------------LSEKYQQAENERRNQDETITKLKKEL----L 744

Query: 1145 QEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLE 1204
            ++  +  ++   LQ+Q  +    LQ+   K+   E LN +        ++ +++ +++L+
Sbjct: 745  KQTNDHQKQVKTLQDQQKQSQEMLQQ---KLQSFERLNEQNQMIICEQKKLLHESQAQLQ 801

Query: 1205 QLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQRE--ADFQKTEHELRVQLS 1262
            ++N EN+ LL   +E   S+    +    E+ +  +  L Q+E   + Q   H+ + +  
Sbjct: 802  KVNLENEALLQNNSESMQSMKEQYELLALELNQTKQVVLDQQELIQNQQLLHHDTQQECY 861

Query: 1263 AFESKYEQLLDSVQSSTQEETNKIV--TMEQVTSLQNKLQDKEE-HLRN--LQEKYADVI 1317
             F+ + EQ  D V    Q E  K +   +  +  L++ L+  E+ H+ N    E+ +  +
Sbjct: 862  KFKKQIEQ-QDIVNKQNQSELGKTIQDQINLINQLKSNLEATEKRHIENKITAEQLSQTL 920

Query: 1318 NQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSY----KQMQEQSILNINEE 1373
               +   +++  E                     L+ + Q +    KQ+Q+   L  N+ 
Sbjct: 921  ITTQSEITQLRFESTQLNNTIEQNSKTIQDLQSQLQIDQQQHEIELKQIQKNLDLVQNQS 980

Query: 1374 NAQLKKSSXXXXXXXXXXXXRVNDAEAKVLE--LTHQLELK------DSEIYQKTHEYTI 1425
            N + +               ++ +   +       HQ+++K      D  + Q+ ++   
Sbjct: 981  NQEKESIILELHKQIQEFQEQLQNQRDQYQHDVQQHQIQIKLNQERFDLVLQQEINQINC 1040

Query: 1426 TLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHY-------ETMQK 1478
             + Q+    E  +Q  ++  K +E+   + + +   + L+   N N Y       ET+Q+
Sbjct: 1041 QMEQQISTKEEEKQGFLDQIKALENKIVQLDQKNKEIYLQSQSNQNLYRQLIEQLETLQQ 1100

Query: 1479 ESEIERVK---LIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVT 1535
            ES+ E++K   L+++ + KI  ++ +N + +E+ K L E++  T+E +  +E  +I+++ 
Sbjct: 1101 ESQNEQLKWKDLLQQKDEKI-RTIEINSK-SEIGK-LNEQLIHTSERRAQIEQDQIKLIE 1157

Query: 1536 LNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDLAMYM 1595
              ++ITN Q + +      QK     S  K   +  LD   N+EL   +     ++++Y 
Sbjct: 1158 -QEQITN-QELQKLKEQLEQKQNEIDSIDKLLNERVLD---NEELNGKLILVSKEMSLYK 1212

Query: 1596 LHQRDVR 1602
               +D++
Sbjct: 1213 DQNKDLQ 1219



 Score = 62.5 bits (145), Expect = 9e-08
 Identities = 103/523 (19%), Positives = 223/523 (42%), Gaps = 43/523 (8%)

Query: 386  WSQLSSETLNQDTDKKINKNE-IAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXG 444
            ++QL  E L+   +   N+ + IA    +I +L    V +E   +EK             
Sbjct: 1345 YNQLKQEELDNVLNLLKNREQQIADQNELINNLQILQVKQEQDYNEKLNNLNQVSMQSSS 1404

Query: 445  KDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEI--KDVNVKDLI 502
            + + + Q+  + Q   E  +   +  N E++ EI K Q+   Q+LN+++  KD  +++  
Sbjct: 1405 EQSELKQIVEQVQMEKEKITEELLKKN-ENLKEIVKNQQTTCQQLNEQLSSKDTELQEQG 1463

Query: 503  EKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSK-VSDSNKEIVRLT 561
              ++  + Q+ QLN+E+      ++  KS   LK+ Q++  I+   + +   + ++    
Sbjct: 1464 ILIEQYQSQVLQLNEELTL----IMDEKSQQNLKIHQLRTNIEKIQQDLEVKSIQLQNSD 1519

Query: 562  EELHHLSQKVAELEEEKGNLQLHL-VDYDSGRMIESDVYKKMIEMENLAETRLKAISLLE 620
             E  +  Q+      E GN    L V     +   S + +++ + EN  E RLK   + E
Sbjct: 1520 LESENQKQQFESQLNELGNQNKELFVRLSELQEENSTLIEQVRKREN--EYRLKVFEMGE 1577

Query: 621  SQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELAL 680
              +F+  ++  I Q    E+   ++++S+       S+IK+   +E +D  S     +  
Sbjct: 1578 KNRFENEEQNKINQILQQELS--ISEVSEENVINALSQIKN-EFQELLDKQSQYSTLIFQ 1634

Query: 681  VIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISE--LLAK 738
            +   L  D E+     +D+E   + I N++   I    D+ DK +K+  E   E  +L K
Sbjct: 1635 LYSELLTDDEE-----EDVEKQIQVISNQMVGLI----DVRDKYKKIENEFEGEGDILVK 1685

Query: 739  INHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERK 798
            I   + S+ + Q      I+  + Y + ++  + ++                 R +L  +
Sbjct: 1686 IKELKLSEQKKQSSNSQDIKSIEAYSQLLDGLMQEFLHN--------------RVNLTMQ 1731

Query: 799  ADQLGSYLQEKQKA-YSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQI 857
            +  + S L E+Q+   +EY  +  EL N+L       + ++     ++   + + K  Q 
Sbjct: 1732 S--MKSLLTEQQRQNVNEYRKKIGELQNKLLQAEKQQKCIDDTKFNLQQYQQIVDKSEQK 1789

Query: 858  LLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQL 900
             +      +  +  +Q+    + ++ +  DL + +S ++   +
Sbjct: 1790 AMYYEMECKKLVQQIQEMKQRMPQRISLNDLDQDQSEQHSLNI 1832


>UniRef50_Q2NHV1 Cluster: Putative uncharacterized protein; n=1;
            Methanosphaera stadtmanae DSM 3091|Rep: Putative
            uncharacterized protein - Methanosphaera stadtmanae
            (strain DSM 3091)
          Length = 1104

 Score =  141 bits (341), Expect = 2e-31
 Identities = 203/981 (20%), Positives = 436/981 (44%), Gaps = 105/981 (10%)

Query: 392  ETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQ 451
            E  +Q++   +N+  ++K E  I++L   +  ++  ISE +             + L  +
Sbjct: 98   EVESQNSGSSLNEMVLSKYENQIKALEDKIQTQKTTISELEEAANNSNDYLAEINRLKEE 157

Query: 452  ---LQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSA 508
               LQ E  Q         +   T ++ EI  ++ QL  E++   +D  +K   E++   
Sbjct: 158  KSLLQSESSQTEVNQLKSIIEKQTVELKEIPILKNQLTMEVSS--RDQKIKKYEEEIDLL 215

Query: 509  EEQITQLNDEIDAANKNMIKVK---SNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELH 565
             E++ + N+++ +  +++I+ +   S +KL++ Q +K +    + S  +K    LT ++ 
Sbjct: 216  NEKLGE-NEDVSSIKEDLIQKEDEISKYKLEILQFEKQVAALKENSSEDKS-EDLTAQIT 273

Query: 566  HLSQKVAELEEEKGNLQLHLVDYDSGRM--IESDVYKKMIEMENLAETRLKAISLLESQK 623
             L  K+A LE E  +L+   V  D   +  +  D+ KK  E+ +L     +     +  +
Sbjct: 274  DLESKIAFLEHENNSLREGNVTSDKQGLDSLIEDITKKSNELIDLRSKYQRLQDTNKINE 333

Query: 624  FDLVQELHILQQKYDEVED-KLADISQLQSDQVCSEIKSVH--LEEQIDALSASKKELAL 680
            F ++ EL     K +E  D K +D+S+    ++ SE K +   L E+   LS S+ E+ L
Sbjct: 334  FKII-ELENENAKLNESIDLKESDVSETVDLELISENKELKNTLLEKEQLLSQSENEVNL 392

Query: 681  VIENLKLDKEQLYGTIKDLENDKEDIM---NKLQNYIQENMDLTDKLEKM-SAEKISELL 736
            +   +  ++ ++    + L   +ED+    NKLQ+   +  DL D + K+ S EK  EL 
Sbjct: 393  LKNTILKNQTEVDDLSEKLAQSREDVTTLNNKLQDSQLKVGDLNDDVLKLKSLEKTIELK 452

Query: 737  -------------AKINHEEQSKIQTQF----GIDAKIQERDLYIENIESELSKYKSRIC 779
                          K N++   K Q        +  ++ E+DL I ++ S+    +S+I 
Sbjct: 453  DMDYSKLEDKYQQLKDNYDNLEKSQVDVDELSSLKEQVNEKDLNIRSLTSQNEASESKIA 512

Query: 780  RLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQE-----DELVNRLA----VL 830
             LE+++   ++    L+ + D       +K+   +  T QE      EL  + A    + 
Sbjct: 513  ELEKTLTTRDNEISELKSELDSFD--FSKKESEINNATNQEIKSIKKELYTKDAEFDKLK 570

Query: 831  MDHDRVVEKQLLEIEHENKELQK---KNQILLEENQNLQISLSDMQQHYNALVEKANRTD 887
            +D++++ +    +I   N+ L K   +N+ +L E + L+ SL       N L ++ N  +
Sbjct: 571  LDYNQLRKNSSKQINELNEALDKFTNENEKILTEKKYLEDSLDSKNSLLNKLEQENNSLN 630

Query: 888  LAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLN 947
            L   +       L+     +KR   E   L+ Q  ++  D       ++E    +   LN
Sbjct: 631  LIIKDKDSNYNVLKKKFQEIKRNNEEQINLLKQDVQDKNDKIAALPQKLELKDIEISQLN 690

Query: 948  EKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELN---KMNLELIDKHVQKQQTQSPDYT 1004
            +  + +   V     +++  +N ++     +++LN     N  +ID+ ++ ++ +     
Sbjct: 691  KIVKSHENDVLSKNNEIKTLRNKVQESREVIKQLNDKLSENSVVIDEKIRSKEDEIFKLK 750

Query: 1005 EQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEM 1064
            + + N +N       +KDEEI  L            S++S    K+ + T  + ++  ++
Sbjct: 751  DNFKNSVN-------EKDEEISRLK-----------SLLSQRNYKIDELTENVGSLNHDL 792

Query: 1065 QRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMI--ISSTIEPMS 1122
            + +S +  D+K+   + + +++ +DD I +  E        I + E  I   +  IE ++
Sbjct: 793  EVLSFKFEDNKEQFNKCEEIIQAKDDVISKKDELIEDINQQINRLENKIKLKNDDIEELN 852

Query: 1123 DDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLN 1182
            DD +  D              ++EE         + E + KLN +L +  ++I + +TL 
Sbjct: 853  DDLSKKDTLIS---------NLKEE---------ISESNLKLN-KLDDLSSQIKENDTLI 893

Query: 1183 TELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQH 1242
             +L     + ++++ +    + +L+T+  + ++ + EL    +  ++     ++E   Q 
Sbjct: 894  EKLNDELALKEQEVQE---NVRELDTDKSH-ITELKELIERKNKDIEDHKKLLSEKNTQL 949

Query: 1243 LAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQE----ETNKIVTMEQVTSLQNK 1298
            L  +  D +   +EL V+ S   + Y+Q + S+ +  ++    +T     +EQ++ L+ +
Sbjct: 950  LEFK--DLKPRINELEVEKSDMMANYQQQITSLNADLEKAQLFKTENEKKIEQISQLKEQ 1007

Query: 1299 LQDKEEHLRNLQE--KYADVI 1317
            L DK+  + + ++  KY DV+
Sbjct: 1008 LNDKDAQIASYEQYKKYFDVL 1028



 Score =  135 bits (326), Expect = 1e-29
 Identities = 229/1113 (20%), Positives = 504/1113 (45%), Gaps = 114/1113 (10%)

Query: 493  IKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSD 552
            +KDV  ++L E +KS  ++I  L ++++  NK+   +KSN  +K   +Q   +N +  + 
Sbjct: 4    LKDVESEELRELVKSCFKEINTLKEQLNDENKD---IKSNKVVKNVLIQSESNNTNLQAK 60

Query: 553  SNKEIVRLTEELHHLSQKVAELEE-----EKGNLQLHLVD-YDSGRMIESDVYKKMIEME 606
             N+   ++ ++  +L +K  EL+E     ++ +LQ+  V+  +SG  +   V  K     
Sbjct: 61   INELTDKVHKQDTYLKEKELELQEMETRLKEKDLQIKEVESQNSGSSLNEMVLSKY---- 116

Query: 607  NLAETRLKAI-SLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLE 665
               E ++KA+   +++QK  + +    L++  +   D LA+I++L+ ++  S ++S   +
Sbjct: 117  ---ENQIKALEDKIQTQKTTISE----LEEAANNSNDYLAEINRLKEEK--SLLQSESSQ 167

Query: 666  EQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKL- 724
             +++ L +  ++  + ++ + + K QL      +E    D   K++ Y +E   L +KL 
Sbjct: 168  TEVNQLKSIIEKQTVELKEIPILKNQL-----TMEVSSRD--QKIKKYEEEIDLLNEKLG 220

Query: 725  EKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEES 784
            E      I E L +   +E SK + +  +  + Q   L   + E +     ++I  LE  
Sbjct: 221  ENEDVSSIKEDLIQ-KEDEISKYKLEI-LQFEKQVAALKENSSEDKSEDLTAQITDLESK 278

Query: 785  IAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELV---NRLAVLMDHDRVVEKQL 841
            IA +E    SL  +   + S  Q       + T + +EL+   ++   L D +++ E ++
Sbjct: 279  IAFLEHENNSL--REGNVTSDKQGLDSLIEDITKKSNELIDLRSKYQRLQDTNKINEFKI 336

Query: 842  LEIEHENKELQ-----KKNQI-------LLEENQNLQISLSDMQQHYNALVEKANRTDLA 889
            +E+E+EN +L      K++ +       L+ EN+ L+ +L + +Q    L +  N  +L 
Sbjct: 337  IELENENAKLNESIDLKESDVSETVDLELISENKELKNTLLEKEQ---LLSQSENEVNLL 393

Query: 890  ESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEK 949
            ++   K QT++ DL   L +   +  TL      +++D +++     +  ++ K +    
Sbjct: 394  KNTILKNQTEVDDLSEKLAQSREDVTTL----NNKLQDSQLKVGDLNDDVLKLKSLEKTI 449

Query: 950  YEKNIEYVTQLEAQLQEYKNNIENL---NMNVEELNKMNLELIDKHVQKQQTQSPDYTEQ 1006
              K+++Y ++LE + Q+ K+N +NL    ++V+EL+ +  ++ +K +  +   S +   +
Sbjct: 450  ELKDMDY-SKLEDKYQQLKDNYDNLEKSQVDVDELSSLKEQVNEKDLNIRSLTSQNEASE 508

Query: 1007 YINEINKLNALLKQKDEEIIALNQKIN----NAQVSYMSMVSDYESKLAQFTTKLENMEE 1062
              ++I +L   L  +D EI  L  +++    + + S ++  ++ E K  +     ++ E 
Sbjct: 509  --SKIAELEKTLTTRDNEISELKSELDSFDFSKKESEINNATNQEIKSIKKELYTKDAEF 566

Query: 1063 EMQRVSKQLL---DSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIE 1119
            +  ++    L    SKQ NE  + L +  ++  K L E K   E ++     ++  + +E
Sbjct: 567  DKLKLDYNQLRKNSSKQINELNEALDKFTNENEKILTEKKY-LEDSLDSKNSLL--NKLE 623

Query: 1120 PMSDDANNV----DXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKI 1175
              ++  N +    D            +K   EE+    +  +Q+++ K+    Q+   K 
Sbjct: 624  QENNSLNLIIKDKDSNYNVLKKKFQEIKRNNEEQINLLKQDVQDKNDKIAALPQKLELKD 683

Query: 1176 IQLETLNTELTGH--DVVNQ-EQINQLKSKLEQ----LNTENDNLLSTVAELRSSISSAV 1228
            I++  LN  +  H  DV+++  +I  L++K+++    +   ND L      +   I S  
Sbjct: 684  IEISQLNKIVKSHENDVLSKNNEIKTLRNKVQESREVIKQLNDKLSENSVVIDEKIRSKE 743

Query: 1229 DQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQE-ETNKIV 1287
            D+  F++ + +K  + +++ +  +    L+  LS    K ++L ++V S   + E     
Sbjct: 744  DEI-FKLKDNFKNSVNEKDEEISR----LKSLLSQRNYKIDELTENVGSLNHDLEVLSFK 798

Query: 1288 ---TMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIE---DEKVAFXXXXXXX 1341
                 EQ    +  +Q K++ +    E   D+  QI  L ++I+   D+           
Sbjct: 799  FEDNKEQFNKCEEIIQAKDDVISKKDELIEDINQQINRLENKIKLKNDDIEELNDDLSKK 858

Query: 1342 XXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAE-- 1399
                     ++   N    ++ + S   I E +  ++K +             V + +  
Sbjct: 859  DTLISNLKEEISESNLKLNKLDDLS-SQIKENDTLIEKLNDELALKEQEVQENVRELDTD 917

Query: 1400 -AKVLELTHQLELKDSEIYQKTHEYTITLTQRND---EFENVRQQLVEYEKRIEDLTYEK 1455
             + + EL   +E K+ +I     ++   L+++N    EF++++ ++ E E    D+    
Sbjct: 918  KSHITELKELIERKNKDI----EDHKKLLSEKNTQLLEFKDLKPRINELEVEKSDMMANY 973

Query: 1456 ESELAILRLKMHENANHYETMQKESEIERV-KLIEELNVKITESVSLNKQVAELNKALEE 1514
            + ++  L   + E A  ++T + E +IE++ +L E+LN K  +  S      +  K  + 
Sbjct: 974  QQQITSLNADL-EKAQLFKT-ENEKKIEQISQLKEQLNDKDAQIASYE----QYKKYFDV 1027

Query: 1515 EVAKTNEMQTALENQEIEIVTLNDEITNLQNMV 1547
             VAK     T+ ++Q   ++      T L N +
Sbjct: 1028 LVAKPLPSLTSFQSQIYRLLPDAMSATELYNYI 1060



 Score =  120 bits (288), Expect = 4e-25
 Identities = 205/977 (20%), Positives = 426/977 (43%), Gaps = 102/977 (10%)

Query: 151  IKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXX 210
            + + +N +  L+ K++  +TTI +L+E  N  +  +   N+                   
Sbjct: 113  LSKYENQIKALEDKIQTQKTTISELEEAANNSNDYLAEINRLKEEKSLLQSESSQT---- 168

Query: 211  XEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLE 270
              +  Q  + +++  + ++ E    K +L  ++ S+D +I   EE   LL     E + +
Sbjct: 169  --EVNQLKSIIEKQTVELK-EIPILKNQLTMEVSSRDQKIKKYEEEIDLLNEKLGE-NED 224

Query: 271  HSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIEL 330
             S + ++L Q                KQ    +  ++   E+K     A +T+L  KI  
Sbjct: 225  VSSIKEDLIQKEDEISKYKLEILQFEKQV---AALKENSSEDKSEDLTAQITDLESKIAF 281

Query: 331  LEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLS 390
            LEH N  +R+ N   + +    G +S  +   +KK + LI           ++S + +L 
Sbjct: 282  LEHENNSLREGNVTSDKQ----GLDS-LIEDITKKSNELID----------LRSKYQRL- 325

Query: 391  SETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIA 450
                 QDT+ KIN+ +I +LE     LN+ +  KE  +SE              K+TL+ 
Sbjct: 326  -----QDTN-KINEFKIIELENENAKLNESIDLKESDVSE-TVDLELISENKELKNTLLE 378

Query: 451  QLQL----EHQQHMEGPSLIHVGTNTEDVNE-IAKVQEQ---LKQELND-EIKDVNVKDL 501
            + QL    E++ ++   +++   T  +D++E +A+ +E    L  +L D ++K  ++ D 
Sbjct: 379  KEQLLSQSENEVNLLKNTILKNQTEVDDLSEKLAQSREDVTTLNNKLQDSQLKVGDLNDD 438

Query: 502  IEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFS----KVSDSNKEI 557
            + KLKS E+ I   + +         ++K N+   L++ Q  +D  S    +V++ +  I
Sbjct: 439  VLKLKSLEKTIELKDMDYSKLEDKYQQLKDNYD-NLEKSQVDVDELSSLKEQVNEKDLNI 497

Query: 558  VRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAI- 616
              LT +      K+AELE+        + +  S  +   D  KK  E+ N     +K+I 
Sbjct: 498  RSLTSQNEASESKIAELEKTLTTRDNEISELKS-ELDSFDFSKKESEINNATNQEIKSIK 556

Query: 617  -------SLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQID 669
                   +  +  K D  Q      ++ +E+ + L   +  +++++ +E K  +LE+ +D
Sbjct: 557  KELYTKDAEFDKLKLDYNQLRKNSSKQINELNEALDKFTN-ENEKILTEKK--YLEDSLD 613

Query: 670  ALSASKKELALVIENLKL---DKEQLYGTIK----DLENDKEDIMNKLQNYIQENMD--- 719
            + ++   +L     +L L   DK+  Y  +K    +++ + E+ +N L+  +Q+  D   
Sbjct: 614  SKNSLLNKLEQENNSLNLIIKDKDSNYNVLKKKFQEIKRNNEEQINLLKQDVQDKNDKIA 673

Query: 720  -LTDKLEKMSAE--KISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKS 776
             L  KLE    E  ++++++    ++  SK      +  K+QE    I+ +  +LS+  S
Sbjct: 674  ALPQKLELKDIEISQLNKIVKSHENDVLSKNNEIKTLRNKVQESREVIKQLNDKLSE-NS 732

Query: 777  RICRLEESIAVMEDRRYSL----ERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMD 832
             +  ++E I   ED  + L    +   ++    +   +   S+   + DEL   +  L +
Sbjct: 733  VV--IDEKIRSKEDEIFKLKDNFKNSVNEKDEEISRLKSLLSQRNYKIDELTENVGSL-N 789

Query: 833  HDRVVEKQLLEIEHENKELQKKNQILLEENQNLQIS---LSDMQQHYNALVEKANRTDLA 889
            HD  +E    + E   ++  K  +I+  ++  +      + D+ Q  N L  K    +  
Sbjct: 790  HD--LEVLSFKFEDNKEQFNKCEEIIQAKDDVISKKDELIEDINQQINRLENKIKLKNDD 847

Query: 890  ESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEK 949
              E     ++   L SNLK    E   L + K  ++     E +T IE    +  +  ++
Sbjct: 848  IEELNDDLSKKDTLISNLKEEISE-SNLKLNKLDDLSSQIKENDTLIEKLNDELALKEQE 906

Query: 950  YEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYIN 1009
             ++N+  +   ++ + E K  IE  N ++E+  K+   L +K+ Q  + +     +  IN
Sbjct: 907  VQENVRELDTDKSHITELKELIERKNKDIEDHKKL---LSEKNTQLLEFKD---LKPRIN 960

Query: 1010 EIN-KLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVS 1068
            E+  + + ++    ++I +LN  +  AQ+      ++ E K+ Q    +  ++E++    
Sbjct: 961  ELEVEKSDMMANYQQQITSLNADLEKAQL----FKTENEKKIEQ----ISQLKEQLNDKD 1012

Query: 1069 KQLLDSKQHNEELQILV 1085
             Q+   +Q+ +   +LV
Sbjct: 1013 AQIASYEQYKKYFDVLV 1029



 Score =  107 bits (256), Expect = 3e-21
 Identities = 148/753 (19%), Positives = 348/753 (46%), Gaps = 65/753 (8%)

Query: 843  EIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDL----AESESTKYQT 898
            ++  ENK++ K N+++       + + +++Q   N L +K ++ D      E E  + +T
Sbjct: 29   QLNDENKDI-KSNKVVKNVLIQSESNNTNLQAKINELTDKVHKQDTYLKEKELELQEMET 87

Query: 899  QLRDLESNLKRITHEHQ-----TLIVQK-KKEIEDLEIEFNTQIESAIRDKKVLNEKYEK 952
            +L++ +  +K +  ++       +++ K + +I+ LE +  TQ ++ I +   L E    
Sbjct: 88   RLKEKDLQIKEVESQNSGSSLNEMVLSKYENQIKALEDKIQTQ-KTTISE---LEEAANN 143

Query: 953  NIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEIN 1012
            + +Y+ ++  +L+E K+ +++ +   E +N++   +I+K   + + + P    Q   E++
Sbjct: 144  SNDYLAEIN-RLKEEKSLLQSESSQTE-VNQLK-SIIEKQTVELK-EIPILKNQLTMEVS 199

Query: 1013 KLNALLKQKDEEIIALNQKIN-NAQVSYMSM-VSDYESKLAQFTTKLENMEEEMQRVSKQ 1070
              +  +K+ +EEI  LN+K+  N  VS +   +   E +++++  KLE ++ E Q  + +
Sbjct: 200  SRDQKIKKYEEEIDLLNEKLGENEDVSSIKEDLIQKEDEISKY--KLEILQFEKQVAALK 257

Query: 1071 LLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDX 1130
               S+  +E+L   + + + +I  L+    +       ++   + S IE ++  +N +  
Sbjct: 258  ENSSEDKSEDLTAQITDLESKIAFLEHENNSLREGNVTSDKQGLDSLIEDITKKSNELID 317

Query: 1131 XXXXXXXXXXXLKVQEEE--EFIQERSVLQEQSAKLNTELQECYT-KIIQ--LETLNTEL 1185
                        K+ E +  E   E + L E      +++ E    ++I    E  NT L
Sbjct: 318  LRSKYQRLQDTNKINEFKIIELENENAKLNESIDLKESDVSETVDLELISENKELKNTLL 377

Query: 1186 TGHDVVNQEQ--INQLKSKLEQLNTENDNLLSTVAELR---SSISSAVDQRGFEIAELWK 1240
                +++Q +  +N LK+ + +  TE D+L   +A+ R   +++++ +     ++ +L  
Sbjct: 378  EKEQLLSQSENEVNLLKNTILKNQTEVDDLSEKLAQSREDVTTLNNKLQDSQLKVGDLND 437

Query: 1241 QHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQ 1300
              L  +    +KT     +  S  E KY+QL D+  +  + +    V +++++SL+ ++ 
Sbjct: 438  DVLKLKS--LEKTIELKDMDYSKLEDKYQQLKDNYDNLEKSQ----VDVDELSSLKEQVN 491

Query: 1301 DKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYK 1360
            +K+ ++R+L  +            +E  + K+A                 +L++E  S+ 
Sbjct: 492  EKDLNIRSLTSQ------------NEASESKIA---ELEKTLTTRDNEISELKSELDSFD 536

Query: 1361 QMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTH-QLELKDSEIYQK 1419
              +++S +N N  N ++K                  DAE   L+L + QL    S+   +
Sbjct: 537  FSKKESEIN-NATNQEIKSIKKELYT---------KDAEFDKLKLDYNQLRKNSSKQINE 586

Query: 1420 THEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKE 1479
             +E     T  N++    ++ L +       L  + E E   L L + +  ++Y  ++K+
Sbjct: 587  LNEALDKFTNENEKILTEKKYLEDSLDSKNSLLNKLEQENNSLNLIIKDKDSNYNVLKKK 646

Query: 1480 SEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDE 1539
             +  +    E++N+   +    N ++A L + LE +  + +++   +++ E ++++ N+E
Sbjct: 647  FQEIKRNNEEQINLLKQDVQDKNDKIAALPQKLELKDIEISQLNKIVKSHENDVLSKNNE 706

Query: 1540 ITNLQNMVRASSSKIQKHVSFASDTKQGRDEQL 1572
            I  L+N V+ S   I++     S+     DE++
Sbjct: 707  IKTLRNKVQESREVIKQLNDKLSENSVVIDEKI 739



 Score = 96.3 bits (229), Expect = 6e-18
 Identities = 145/692 (20%), Positives = 315/692 (45%), Gaps = 68/692 (9%)

Query: 147  LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINE-KDQIIEAKNKATTXXXXXXXXXXX 205
            L NT+ EK+  LS  + ++ +++ TIL  Q ++++  +++ +++   TT           
Sbjct: 372  LKNTLLEKEQLLSQSENEVNLLKNTILKNQTEVDDLSEKLAQSREDVTT----------- 420

Query: 206  XXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARF 265
                  +D++ ++  + ++ + +++        L K IE KD+  S LE+  + L+   +
Sbjct: 421  -LNNKLQDSQLKVGDLNDDVLKLKS--------LEKTIELKDMDYSKLEDKYQQLK-DNY 470

Query: 266  EISLEHSKL-AQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTEL 324
            + +LE S++   EL                L  Q+ E S  +  E+E+  +     ++EL
Sbjct: 471  D-NLEKSQVDVDELSSLKEQVNEKDLNIRSLTSQN-EASESKIAELEKTLTTRDNEISEL 528

Query: 325  TKKIELLEHLNCQI---RQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASK 381
              +++  +    +      TN+E+++    + T+           + L  RK+     ++
Sbjct: 529  KSELDSFDFSKKESEINNATNQEIKSIKKELYTKDAEFDKLKLDYNQL--RKNSSKQINE 586

Query: 382  MKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDT----XXXX 437
            +     + ++E     T+KK  ++ +     ++  L ++      +I +KD+        
Sbjct: 587  LNEALDKFTNENEKILTEKKYLEDSLDSKNSLLNKLEQENNSLNLIIKDKDSNYNVLKKK 646

Query: 438  XXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEI-KDV 496
                    +  I  L+ + Q   +  + +      +D+ EI+++ + +K   ND + K+ 
Sbjct: 647  FQEIKRNNEEQINLLKQDVQDKNDKIAALPQKLELKDI-EISQLNKIVKSHENDVLSKNN 705

Query: 497  NVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNF-SKVSDSNK 555
             +K L  K++ + E I QLND++   ++N + +    + K  ++ K  DNF + V++ ++
Sbjct: 706  EIKTLRNKVQESREVIKQLNDKL---SENSVVIDEKIRSKEDEIFKLKDNFKNSVNEKDE 762

Query: 556  EIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKA 615
            EI RL   L   + K+ EL E  G+L  H ++  S +    D  ++  + E + + +   
Sbjct: 763  EISRLKSLLSQRNYKIDELTENVGSLN-HDLEVLSFKF--EDNKEQFNKCEEIIQAKDDV 819

Query: 616  ISLLESQKFDLVQELHILQQKY----DEVEDKLADISQLQS--DQVCSEIKSVHLE-EQI 668
            IS  +    D+ Q+++ L+ K     D++E+   D+S+  +    +  EI   +L+  ++
Sbjct: 820  ISKKDELIEDINQQINRLENKIKLKNDDIEELNDDLSKKDTLISNLKEEISESNLKLNKL 879

Query: 669  DALSASKKELALVIENLK----LDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKL 724
            D LS+  KE   +IE L     L ++++   +++L+ DK  I    +   ++N D+ D  
Sbjct: 880  DDLSSQIKENDTLIEKLNDELALKEQEVQENVRELDTDKSHITELKELIERKNKDIEDH- 938

Query: 725  EKMSAEKISELL------AKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRI 778
            +K+ +EK ++LL       +IN  E  K        A  Q++   I ++ ++L K +   
Sbjct: 939  KKLLSEKNTQLLEFKDLKPRINELEVEKSDMM----ANYQQQ---ITSLNADLEKAQLFK 991

Query: 779  CRLEESIAVMEDRRYSLERKADQLGSYLQEKQ 810
               E+ I  +   +  L  K  Q+ SY Q K+
Sbjct: 992  TENEKKIEQISQLKEQLNDKDAQIASYEQYKK 1023


>UniRef50_A0DKF0 Cluster: Chromosome undetermined scaffold_54, whole
            genome shotgun sequence; n=3; Paramecium tetraurelia|Rep:
            Chromosome undetermined scaffold_54, whole genome shotgun
            sequence - Paramecium tetraurelia
          Length = 1892

 Score =  140 bits (339), Expect = 3e-31
 Identities = 207/1086 (19%), Positives = 462/1086 (42%), Gaps = 90/1086 (8%)

Query: 476  NEIAKVQEQLKQELNDEI--KDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNH 533
            NE  +++ +  ++LN ++  K+  ++ ++E+ +   ++   LN++I  AN+   +VK  +
Sbjct: 617  NEQLELKSRAVEQLNQQLFQKEQEIQQIVEQNQIHIQEAQHLNEQIGEANQ---EVKQLN 673

Query: 534  KLKLKQMQKTIDNFSKVSDSNKEIVRLTE-ELHHLSQKVAELEEEKGNLQLHLVDYDSGR 592
            +  L Q Q  ++      DS +  V L++ E   L  ++  L+ EK NLQ+         
Sbjct: 674  QQLLSQ-QNELEQAKLQQDSLQNTVHLSKLENDQLKLQIETLKTEKQNLQVQ------SN 726

Query: 593  MIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQS 652
              + D+   + + +   ET L  +     ++ +L+ ++H   ++ +E++++   +++ + 
Sbjct: 727  QNQDDLSNSLQQQKQQNETLLSQLQNSIQEQNNLINQIHSQLKENNELKEQNLLLNREKQ 786

Query: 653  DQVCSEIKSVH-LEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQ 711
            D      K +  L  Q+  L   +++  LV +N      +L   IK+ + +  +I N+ +
Sbjct: 787  DIQLQNNKQIDDLLNQVKQLIQKQEQQELVYQN------ELQTIIKNSKVENTNIQNEYE 840

Query: 712  NYIQENMDLTD-KLEKMSAEKISELLAKINHEEQSKIQTQFG--------IDAKIQERDL 762
            + IQ  +     ++E++  E   +L   +N +E S IQTQ          ++ ++QE+ L
Sbjct: 841  SQIQTIVKKHQMQIEELKDENKRQLDQFVNQQE-SVIQTQINQLQNQIQQLNKELQEKQL 899

Query: 763  YIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDE 822
             + N   E    K    +LE+ I   E+ +  ++++  +L    +E  +A  E   +E+E
Sbjct: 900  QLVNKNKEFELLKENQTKLEQQI---EENKAVMKQQEQELLIKKEELNQAVQEIITKEEE 956

Query: 823  LVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQIL------LEENQN-LQISLSDMQQH 875
               +LA + +  +  E   LE++  +K + +K  ++      +E+ ++ LQI   D    
Sbjct: 957  FQEQLAQVNEKQKEFEDNCLELK--SKAIPEKESVIEQLRADIEQKESELQIQNEDFINQ 1014

Query: 876  YNALVEKANRTDLAESESTKYQTQLRDLESNLK---RITHEHQTLIVQKKKEIEDLEIEF 932
             N L E   + D+   E  K    L D  + LK   ++   +     + K  I+ L  + 
Sbjct: 1015 QNLLFEMIKQKDV---EIKKLTEDLDDHSNRLKEASKVIDRYSNCNSELKGTIDSLNHQL 1071

Query: 933  NTQIESAIRDKKVL-NEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDK 991
              Q +  + D K+  N   +   E +  L   LQ  +N + NL M +EE NK        
Sbjct: 1072 EKQ-QQILNDIKIKENTSTQIYDEKMKSLNEILQSKQNEVANLQMRLEEENK-------- 1122

Query: 992  HVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLA 1051
             V KQQ Q      Q   ++      +K  ++E I   ++I   + S + + S  ++ L 
Sbjct: 1123 -VYKQQNQ------QSSQQMKTTEKRMKDLEKEKINYQEEIQKKETSIIQLESKLQASLK 1175

Query: 1052 QFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKEL-KETKLTFEMNIPKTE 1110
            +        + +++ + +QLL S Q  EE +I V     ++ +L KE  L+ +++     
Sbjct: 1176 EKEIMSNQFKNQIKELQQQLLSSNQGVEEQKIWVIHYKKEVDKLNKEVSLSQQISQQYQS 1235

Query: 1111 GMIISSTIEPMSDDANNV-DXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQ 1169
                +  I+  +   N + D            ++  ++E+     S+ Q+++  L  E  
Sbjct: 1236 QKNDNDQIKQENQKLNKLLDNQQQQIVSLKKEVEQHKQEKSKLVESISQQENRILELEEI 1295

Query: 1170 ECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVD 1229
            +   +I+Q +    + +  +V  Q++  Q +++L+ +  +  +    + E +        
Sbjct: 1296 KLQKQILQGKVSELQKSQQEV--QQKYQQAQAQLQSVQDDLQHSKKEIQETKQKNKVLAQ 1353

Query: 1230 QRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTM 1289
            Q+  E+++  ++ +A +E    + E   ++Q+   +S+ EQ   ++Q     E  K+   
Sbjct: 1354 QQQNEMSKFNQEIIAIQE----ELEQSRKIQMEIKKSEQEQREQNMQIRQNYEKLKLENQ 1409

Query: 1290 E---QVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXX 1346
            +   Q+  +Q  ++ ++E +    E    + +Q++    ++E +                
Sbjct: 1410 QLNNQLDEIQQDMKYEKEEVLKKDETIYKLSDQVKYKTQQLEAQNTLINQVEQNKLSQTN 1469

Query: 1347 XXXXDL-RTENQSYKQMQEQSILNINEENAQ-LKKSSXXXXXXXXXXXXRVNDAEAKVLE 1404
                   +  N S +    +  L IN+  ++  K+              +V D + +  +
Sbjct: 1470 QILQQSNQLTNLSKELFSLKQQLQINDAQSESYKREVERLRRELEFQEKQVEDYKQQTKK 1529

Query: 1405 LTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRL 1464
            L+ QL+      ++K H     + + ++    +   L    K ++  T    S+      
Sbjct: 1530 LSQQLD------FEKKHSQKQKIYEASELLSKIDNTLSPI-KGVKGQTLYGSSDS----- 1577

Query: 1465 KMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQT 1524
            K  +     +T Q+E   +       LN        L K+  +L ++LE+++    +++ 
Sbjct: 1578 KTQKRIFQQKTPQREYGFQNSNSASMLNASFNSQDQLAKENRKLKQSLEQKMKIIEQLEQ 1637

Query: 1525 ALENQE 1530
            AL   E
Sbjct: 1638 ALLQSE 1643



 Score =  140 bits (338), Expect = 4e-31
 Identities = 244/1271 (19%), Positives = 542/1271 (42%), Gaps = 108/1271 (8%)

Query: 379  ASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVI--SEKDTXXX 436
            A   +   +Q+  E L +    +IN++ +  L  VI SL +D     YV     K T   
Sbjct: 241  AGSERQKHTQVQGERLREGC--QINRS-LHILGNVINSLVEDKEQNRYVHYRDSKLTFLL 297

Query: 437  XXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDV 496
                    +  LIA +Q  +  + E  S +      + V   A+V E     L + +K+ 
Sbjct: 298  KDSLGGNSRTHLIANIQQSNLFYQETFSTLQFSKRVKQVKNKARVNEDESGSL-ESLKN- 355

Query: 497  NVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKE 556
             +K L ++L      +   +   ++ +K  I +   H +  + +      + K+ +  K 
Sbjct: 356  EIKRLKQELAKWIVGLQTTSKLAESPSKQNIIM---HNINFEDLNAKDQRYIKLEEILK- 411

Query: 557  IVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAI 616
             V L +     +    E+E+    ++     +     +E  + K +I ++N    RLK  
Sbjct: 412  -VYLEQSTESETALYVEIEKYLSGIKELREAFQLSSQLEQQL-KLIIRLQNEQIVRLKHA 469

Query: 617  SLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKS-VHLEEQIDALSASK 675
            +  E    D  +EL         V  K +D  +++     +  K+ + + E +  L+   
Sbjct: 470  NGAEDLSNDYQEELSKALLSQAAVMKKFSDSLRIKEGSAKNVEKAKLQINENVSMLNTIV 529

Query: 676  KELALVI-ENLKLDKE------QLYGTIKD---LENDKEDIMNKLQNYIQENMDLTDKLE 725
              +   + E  KL K+      Q+Y  +++   L+++KE I  KL  ++++   +   L+
Sbjct: 530  TTVNESLDERKKLQKQIQQQFSQVYVPVEEFTQLQSEKEKINEKLTKFVEKEDKIKQSLD 589

Query: 726  KMSAEKISELLAKI-NHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEES 784
            ++      E   KI +H+++     Q     +++ R   +E +  +L + +  I ++ E 
Sbjct: 590  QIGITIHDEDEIKIIDHKQRDLTLDQQNEQLELKSRA--VEQLNQQLFQKEQEIQQIVEQ 647

Query: 785  --IAVMEDRRYSLE-----RKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVV 837
              I + E +  + +     ++  QL   L  +Q    +  +Q+D L N +     H   +
Sbjct: 648  NQIHIQEAQHLNEQIGEANQEVKQLNQQLLSQQNELEQAKLQQDSLQNTV-----HLSKL 702

Query: 838  EKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESEST--K 895
            E   L+++ E  + +K+N + ++ NQN     + +QQ      ++ N T L++ +++  +
Sbjct: 703  ENDQLKLQIETLKTEKQN-LQVQSNQNQDDLSNSLQQQ-----KQQNETLLSQLQNSIQE 756

Query: 896  YQTQLRDLESNLKRITH-EHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKN- 953
                +  + S LK     + Q L++ ++K+  D++++ N QI+  +   K L +K E+  
Sbjct: 757  QNNLINQIHSQLKENNELKEQNLLLNREKQ--DIQLQNNKQIDDLLNQVKQLIQKQEQQE 814

Query: 954  IEYVTQLEAQLQ-----------EYKNNIENL----NMNVEELNKMNLELIDKHVQKQQT 998
            + Y  +L+  ++           EY++ I+ +     M +EEL   N   +D+ V +Q++
Sbjct: 815  LVYQNELQTIIKNSKVENTNIQNEYESQIQTIVKKHQMQIEELKDENKRQLDQFVNQQES 874

Query: 999  QSPDYTEQYINEINKLNALLKQKDEEIIALNQK---INNAQVSYMSMVSDYESKLAQFTT 1055
                   Q  N+I +LN  L++K  +++  N++   +   Q      + + ++ + Q   
Sbjct: 875  VIQTQINQLQNQIQQLNKELQEKQLQLVNKNKEFELLKENQTKLEQQIEENKAVMKQQEQ 934

Query: 1056 KLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMN-IPKTEGMI- 1113
            +L   +EE+ +  ++++  +   EE Q  + + +++ KE ++  L  +   IP+ E +I 
Sbjct: 935  ELLIKKEELNQAVQEIITKE---EEFQEQLAQVNEKQKEFEDNCLELKSKAIPEKESVIE 991

Query: 1114 -ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECY 1172
             + + IE    +    +            +  Q++ E  +    L + S      L+E  
Sbjct: 992  QLRADIEQKESELQIQNEDFINQQNLLFEMIKQKDVEIKKLTEDLDDHS----NRLKEAS 1047

Query: 1173 TKIIQLETLNTELTG------HDVVNQEQI-NQLKSK---LEQLNTENDNLLSTVAELRS 1222
              I +    N+EL G      H +  Q+QI N +K K     Q+  E    L+ + + + 
Sbjct: 1048 KVIDRYSNCNSELKGTIDSLNHQLEKQQQILNDIKIKENTSTQIYDEKMKSLNEILQSKQ 1107

Query: 1223 SISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEE 1282
            +  + +  R  E  +++KQ   Q     + TE  ++  L   +  Y++ +   ++S  + 
Sbjct: 1108 NEVANLQMRLEEENKVYKQQNQQSSQQMKTTEKRMK-DLEKEKINYQEEIQKKETSIIQL 1166

Query: 1283 TNKI---VTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEIL--RSEIE--DEKVAFX 1335
             +K+   +  +++ S Q K Q KE   + L         +I ++  + E++  +++V+  
Sbjct: 1167 ESKLQASLKEKEIMSNQFKNQIKELQQQLLSSNQGVEEQKIWVIHYKKEVDKLNKEVSLS 1226

Query: 1336 XXXXXXXXXXXXXXXDLRTENQSYKQM---QEQSILNINEENAQLKKSSXXXXXXXXXXX 1392
                            ++ ENQ   ++   Q+Q I+++ +E  Q K+             
Sbjct: 1227 QQISQQYQSQKNDNDQIKQENQKLNKLLDNQQQQIVSLKKEVEQHKQEKSKLVESISQQE 1286

Query: 1393 XRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLT 1452
             R+ + E   L+    L+ K SE+ +   E      Q   + ++V+  L   +K I++ T
Sbjct: 1287 NRILELEEIKLQ-KQILQGKVSELQKSQQEVQQKYQQAQAQLQSVQDDLQHSKKEIQE-T 1344

Query: 1453 YEKESELAILRLKMHENANHYETMQKESEIERVKLIE-ELNVKITESVSLNKQVAELNKA 1511
             +K   LA  +       N  E +  + E+E+ + I+ E+     E    N Q+ +  + 
Sbjct: 1345 KQKNKVLAQQQQNEMSKFNQ-EIIAIQEELEQSRKIQMEIKKSEQEQREQNMQIRQNYEK 1403

Query: 1512 LEEEVAKTN----EMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQG 1567
            L+ E  + N    E+Q  ++ ++ E++  ++ I  L + V+  + +++   +  +  +Q 
Sbjct: 1404 LKLENQQLNNQLDEIQQDMKYEKEEVLKKDETIYKLSDQVKYKTQQLEAQNTLINQVEQN 1463

Query: 1568 RDEQLDNTMNK 1578
            +  Q +  + +
Sbjct: 1464 KLSQTNQILQQ 1474



 Score =  110 bits (264), Expect = 4e-22
 Identities = 174/845 (20%), Positives = 381/845 (45%), Gaps = 83/845 (9%)

Query: 306  EKTEIEEKGSLE-IANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSK 364
            E+ + E K  L+   N  E   + ++   L  QI+Q NKEL+ K   +  ++K      +
Sbjct: 855  EELKDENKRQLDQFVNQQESVIQTQI-NQLQNQIQQLNKELQEKQLQLVNKNKEFELLKE 913

Query: 365  KGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMV-IQSLNKDLVD 423
              + L  +        K +     +  E LNQ   + I K E  + ++  +    K+  D
Sbjct: 914  NQTKLEQQIEENKAVMKQQEQELLIKKEELNQAVQEIITKEEEFQEQLAQVNEKQKEFED 973

Query: 424  -----KEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEI 478
                 K   I EK++           K++   +LQ++++  +   +L+      +DV EI
Sbjct: 974  NCLELKSKAIPEKESVIEQLRADIEQKES---ELQIQNEDFINQQNLLFEMIKQKDV-EI 1029

Query: 479  AKVQEQLKQELNDEIKDVNVKDLIEKLKSA-EEQITQLNDEIDAANK--NMIKVKSNHKL 535
             K+ E L    N   +   V D      S  +  I  LN +++   +  N IK+K N   
Sbjct: 1030 KKLTEDLDDHSNRLKEASKVIDRYSNCNSELKGTIDSLNHQLEKQQQILNDIKIKENTST 1089

Query: 536  KL-KQMQKTIDNF--SKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGR 592
            ++  +  K+++    SK ++     +RL EE     Q+  +  ++    +  + D +  +
Sbjct: 1090 QIYDEKMKSLNEILQSKQNEVANLQMRLEEENKVYKQQNQQSSQQMKTTEKRMKDLEKEK 1149

Query: 593  M-IESDVYKK---MIEMENLAETRLKAISLLESQKFDLVQELH--ILQQKYDEVEDKLAD 646
            +  + ++ KK   +I++E+  +  LK   ++ +Q  + ++EL   +L       E K+  
Sbjct: 1150 INYQEEIQKKETSIIQLESKLQASLKEKEIMSNQFKNQIKELQQQLLSSNQGVEEQKIWV 1209

Query: 647  ISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDI 706
            I   +  +V    K V L +QI     S+K      + +K + ++L    K L+N ++ I
Sbjct: 1210 IHYKK--EVDKLNKEVSLSQQISQQYQSQKNDN---DQIKQENQKLN---KLLDNQQQQI 1261

Query: 707  MNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIEN 766
            ++ L+  ++++     KL     E IS+   +I   E+ K+Q Q  +  K+ E     + 
Sbjct: 1262 VS-LKKEVEQHKQEKSKL----VESISQQENRILELEEIKLQKQI-LQGKVSELQKSQQE 1315

Query: 767  IESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQ-EDELVN 825
            ++ +  + ++++  +++ +   +      ++K   L    Q +   +++  I  ++EL  
Sbjct: 1316 VQQKYQQAQAQLQSVQDDLQHSKKEIQETKQKNKVLAQQQQNEMSKFNQEIIAIQEELEQ 1375

Query: 826  RLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQ---HYNALVEK 882
               + M+    ++K   E   +N ++++  + L  ENQ L   L ++QQ   +    V K
Sbjct: 1376 SRKIQME----IKKSEQEQREQNMQIRQNYEKLKLENQQLNNQLDEIQQDMKYEKEEVLK 1431

Query: 883  ANRTDLAESESTKYQTQLRDLESNLKRITHEHQ----TLIVQKKKEIEDLEIE-FNTQIE 937
             + T    S+  KY+TQ  + ++ L     +++      I+Q+  ++ +L  E F+ + +
Sbjct: 1432 KDETIYKLSDQVKYKTQQLEAQNTLINQVEQNKLSQTNQILQQSNQLTNLSKELFSLKQQ 1491

Query: 938  SAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQ 997
              I D +  +E Y++ +E   +L  +L+  +  +E+     ++L++  L+   KH QKQ+
Sbjct: 1492 LQINDAQ--SESYKREVE---RLRRELEFQEKQVEDYKQQTKKLSQQ-LDFEKKHSQKQK 1545

Query: 998  T-QSPDYTEQYINEINKLNALLKQ--------KDEEIIALNQKI--------NNAQVSYM 1040
              ++ +   +  N ++ +  +  Q        K ++ I   QK         N+   S +
Sbjct: 1546 IYEASELLSKIDNTLSPIKGVKGQTLYGSSDSKTQKRI-FQQKTPQREYGFQNSNSASML 1604

Query: 1041 SMVSDYESKLAQFTTKL-ENMEEEM---QRVSKQLLDSKQH----NEELQILVREQDDQI 1092
            +   + + +LA+   KL +++E++M   +++ + LL S+Q     +E+     ++Q+D+I
Sbjct: 1605 NASFNSQDQLAKENRKLKQSLEQKMKIIEQLEQALLQSEQTLKEVHEKANQFCQQQEDEI 1664

Query: 1093 KELKE 1097
            K++K+
Sbjct: 1665 KQIKD 1669



 Score = 77.4 bits (182), Expect = 3e-12
 Identities = 157/870 (18%), Positives = 357/870 (41%), Gaps = 72/870 (8%)

Query: 159  SVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQM 218
            SV+Q ++  ++  I  L +++ EK   +  KNK                    E+ K  M
Sbjct: 874  SVIQTQINQLQNQIQQLNKELQEKQLQLVNKNK----EFELLKENQTKLEQQIEENKAVM 929

Query: 219  TKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQEL 278
             + ++  +  + E     Q ++   E    +++ + E  K  E    E+  +     + +
Sbjct: 930  KQQEQELLIKKEELNQAVQEIITKEEEFQEQLAQVNEKQKEFEDNCLELKSKAIPEKESV 989

Query: 279  EQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQI 338
             +              +  +          E+ ++  +EI  +TE     +L +H N ++
Sbjct: 990  IEQLRADIEQKESELQIQNEDFINQQNLLFEMIKQKDVEIKKLTE-----DLDDHSN-RL 1043

Query: 339  RQTNKELEN----KLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETL 394
            ++ +K ++          GT         K+   L   K   NT++++         ++L
Sbjct: 1044 KEASKVIDRYSNCNSELKGTIDSLNHQLEKQQQILNDIKIKENTSTQIYDE----KMKSL 1099

Query: 395  NQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQL 454
            N+    K  +NE+A L+M ++  N     K Y    + +           KD    ++  
Sbjct: 1100 NEILQSK--QNEVANLQMRLEEEN-----KVYKQQNQQSSQQMKTTEKRMKDLEKEKINY 1152

Query: 455  EHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQ--- 511
            + +   +  S+I + +    +    K +E +  +  ++IK++  + L+   +  EEQ   
Sbjct: 1153 QEEIQKKETSIIQLESK---LQASLKEKEIMSNQFKNQIKELQ-QQLLSSNQGVEEQKIW 1208

Query: 512  ITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKV 571
            +     E+D  NK   +V  + ++  +   +  DN  ++   N+++ +L   L +  Q++
Sbjct: 1209 VIHYKKEVDKLNK---EVSLSQQISQQYQSQKNDN-DQIKQENQKLNKL---LDNQQQQI 1261

Query: 572  AELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELH 631
              L++E   ++ H    +  +++ES + ++   +  L E +L+   +L+ +  +L +   
Sbjct: 1262 VSLKKE---VEQH--KQEKSKLVES-ISQQENRILELEEIKLQK-QILQGKVSELQKSQQ 1314

Query: 632  ILQQKYDEVEDKLADI-SQLQ-SDQVCSEIK---SVHLEEQIDALSASKKELALVIENLK 686
             +QQKY + + +L  +   LQ S +   E K    V  ++Q + +S   +E+  + E L+
Sbjct: 1315 EVQQKYQQAQAQLQSVQDDLQHSKKEIQETKQKNKVLAQQQQNEMSKFNQEIIAIQEELE 1374

Query: 687  LDKEQLYGTIKDLENDKEDIMNKLQNYIQ---ENMDLTDKLEKMSAEKISELLAKINHEE 743
              ++      K  +  +E  M   QNY +   EN  L ++L+++  +   E    +  +E
Sbjct: 1375 QSRKIQMEIKKSEQEQREQNMQIRQNYEKLKLENQQLNNQLDEIQQDMKYEKEEVLKKDE 1434

Query: 744  Q-SKIQTQFGIDA-KIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKAD- 800
               K+  Q      +++ ++  I  +E       ++I +    +  +    +SL+++   
Sbjct: 1435 TIYKLSDQVKYKTQQLEAQNTLINQVEQNKLSQTNQILQQSNQLTNLSKELFSLKQQLQI 1494

Query: 801  ---QLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQL-LEIEHENKELQKKNQ 856
               Q  SY +E ++   E   QE ++ +         + + +QL  E +H  K+   +  
Sbjct: 1495 NDAQSESYKREVERLRRELEFQEKQVED----YKQQTKKLSQQLDFEKKHSQKQKIYEAS 1550

Query: 857  ILLEENQNLQISLSDM--QQHYNALVEKA-NRTDLAESESTKYQTQLRDLESNLKRITHE 913
             LL +  N    +  +  Q  Y +   K   R    ++   +Y  Q  +  S L    + 
Sbjct: 1551 ELLSKIDNTLSPIKGVKGQTLYGSSDSKTQKRIFQQKTPQREYGFQNSNSASMLNASFNS 1610

Query: 914  HQTLIVQKKKEIEDLE--IEFNTQIESA-IRDKKVLNEKYEKNIEYVTQLEAQLQEYKNN 970
               L  + +K  + LE  ++   Q+E A ++ ++ L E +EK  ++  Q E ++++ K+ 
Sbjct: 1611 QDQLAKENRKLKQSLEQKMKIIEQLEQALLQSEQTLKEVHEKANQFCQQQEDEIKQIKDQ 1670

Query: 971  IENLNMNVEELNKMNLELIDKHVQKQQTQS 1000
               L      +     E  ++ + KQ+ Q+
Sbjct: 1671 YSRLEQEHNTI-LAEREYENQQISKQKEQA 1699



 Score = 71.3 bits (167), Expect = 2e-10
 Identities = 176/955 (18%), Positives = 394/955 (41%), Gaps = 79/955 (8%)

Query: 152  KEKDNALSVLQVKMKIMETTILDLQEKINE-KDQIIEAKNKATTXXXXXXXXXXXXXXXX 210
            +E + A+  +  K +  +  +  + EK  E +D  +E K+KA                  
Sbjct: 941  EELNQAVQEIITKEEEFQEQLAQVNEKQKEFEDNCLELKSKAIPEKESVIEQLRADIEQK 1000

Query: 211  XEDTKQQMTKM--QENFIAMEAEWKD-EKQRLLKDIESKDVRISSLEEANKLLEA---AR 264
              + + Q      Q+N +    + KD E ++L +D++    R   L+EA+K+++      
Sbjct: 1001 ESELQIQNEDFINQQNLLFEMIKQKDVEIKKLTEDLDDHSNR---LKEASKVIDRYSNCN 1057

Query: 265  FEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMT-E 323
             E+      L  +LE+               + Q  +   +   EI +    E+AN+   
Sbjct: 1058 SELKGTIDSLNHQLEKQQQILNDIKIKENT-STQIYDEKMKSLNEILQSKQNEVANLQMR 1116

Query: 324  LTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSP-SKKGSPLISRKSGRNTASKM 382
            L ++ ++ +  N Q  Q  K  E ++  +  E         KK + +I  +S    + K 
Sbjct: 1117 LEEENKVYKQQNQQSSQQMKTTEKRMKDLEKEKINYQEEIQKKETSIIQLESKLQASLKE 1176

Query: 383  KSPWS--------QLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDL-----VDKEYVIS 429
            K   S        +L  + L+ +   +  K  +   +  +  LNK++     + ++Y   
Sbjct: 1177 KEIMSNQFKNQIKELQQQLLSSNQGVEEQKIWVIHYKKEVDKLNKEVSLSQQISQQYQSQ 1236

Query: 430  EKDTXXXXXXXXXXGK-----DTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQE- 483
            + D            K        I  L+ E +QH +  S + V + ++  N I +++E 
Sbjct: 1237 KNDNDQIKQENQKLNKLLDNQQQQIVSLKKEVEQHKQEKSKL-VESISQQENRILELEEI 1295

Query: 484  -QLKQELNDEIKDV--NVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQM 540
               KQ L  ++ ++  + +++ +K + A+ Q+  + D++  + K + + K  +K+  +Q 
Sbjct: 1296 KLQKQILQGKVSELQKSQQEVQQKYQQAQAQLQSVQDDLQHSKKEIQETKQKNKVLAQQQ 1355

Query: 541  QKTIDNFSKVSDSNKEIVRLTEELHH-----LSQKVAELEEEKGNLQLHLVDYDSGRMIE 595
            Q  +  F      N+EI+ + EEL       +  K +E E+ + N+Q+   +Y+  ++  
Sbjct: 1356 QNEMSKF------NQEIIAIQEELEQSRKIQMEIKKSEQEQREQNMQIRQ-NYEKLKLEN 1408

Query: 596  SDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQV 655
              +  ++ E++   +   + +   +   + L  ++   + K  ++E +   I+Q++ +++
Sbjct: 1409 QQLNNQLDEIQQDMKYEKEEVLKKDETIYKLSDQV---KYKTQQLEAQNTLINQVEQNKL 1465

Query: 656  CSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQ 715
                + +    Q+  LS   KEL  + + L+++  Q     +++E  + ++  + +  ++
Sbjct: 1466 SQTNQILQQSNQLTNLS---KELFSLKQQLQINDAQSESYKREVERLRRELEFQ-EKQVE 1521

Query: 716  ENMDLTDKL-EKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKY 774
            +    T KL +++  EK         H ++ KI     + +KI      I+ ++ + + Y
Sbjct: 1522 DYKQQTKKLSQQLDFEK--------KHSQKQKIYEASELLSKIDNTLSPIKGVKGQ-TLY 1572

Query: 775  KSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHD 834
             S   + ++ I   +  +     +     S L     +  +   +  +L   L   M   
Sbjct: 1573 GSSDSKTQKRIFQQKTPQREYGFQNSNSASMLNASFNSQDQLAKENRKLKQSLEQKMKII 1632

Query: 835  RVVEKQLLEIEHENKELQKK-NQILLEENQNL-QIS--LSDMQQHYNALV---EKANRTD 887
              +E+ LL+ E   KE+ +K NQ   ++   + QI    S ++Q +N ++   E  N+  
Sbjct: 1633 EQLEQALLQSEQTLKEVHEKANQFCQQQEDEIKQIKDQYSRLEQEHNTILAEREYENQQI 1692

Query: 888  LAESESTKYQTQ-LRDLESNLKRITHEHQTLIVQKKKE-IEDLEIEFNTQIESAIRDKKV 945
              + E   ++ Q L+D     KR +   Q +   K  E ++D+ +          R    
Sbjct: 1693 SKQKEQALFKVQILQDEVLKSKRGSVGSQHIPGSKYSETVQDMSMRETPSSSHRFRLSDG 1752

Query: 946  LNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNK-MNLELIDKHVQKQQTQSPDYT 1004
              + Y   ++  ++L    Q+     + LN  + +L + + LE    +  +   +     
Sbjct: 1753 QFKSYY-GVDAHSKLIYDTQKLLLENQRLNSQMCKLYQILGLEKNRSNKLEDGEKIIQSV 1811

Query: 1005 EQYINEIN--KLNALLKQKDEEIIALNQKINNAQVSYMSMVSD-YESKLAQFTTK 1056
            +  + E+   K+  LLK   +EI  L Q   +  + Y SM  D  ++KL  +  +
Sbjct: 1812 QLLLQEVIVFKIQLLLKDCKQEIQNLIQAQPSRSLKYQSMEKDLQQTKLKYYAVE 1866



 Score = 62.9 bits (146), Expect = 7e-08
 Identities = 161/799 (20%), Positives = 335/799 (41%), Gaps = 76/799 (9%)

Query: 49   ERQIKFERAQKCLENAALVSKRIKEHRKATAELLGRPFVPGISE-SLANT--LKQKEILM 105
            E+Q +FE    CLE   L SK I E +++  E L        SE  + N   + Q+ +L 
Sbjct: 966  EKQKEFE--DNCLE---LKSKAIPE-KESVIEQLRADIEQKESELQIQNEDFINQQNLLF 1019

Query: 106  EKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNALSVLQV-- 163
            E IKQ K++  +  T  +                     + L  TI   ++ L   Q   
Sbjct: 1020 EMIKQ-KDVEIKKLTEDLDDHSNRLKEASKVIDRYSNCNSELKGTIDSLNHQLEKQQQIL 1078

Query: 164  -KMKIMETTILDL-QEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKM 221
              +KI E T   +  EK+   ++I+++K                      + + QQM   
Sbjct: 1079 NDIKIKENTSTQIYDEKMKSLNEILQSKQNEVANLQMRLEEENKVYKQQNQQSSQQMKTT 1138

Query: 222  QENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQX 281
            ++    +E E    K    ++I+ K+  I  LE   +     +  +S +     +EL+Q 
Sbjct: 1139 EKRMKDLEKE----KINYQEEIQKKETSIIQLESKLQASLKEKEIMSNQFKNQIKELQQQ 1194

Query: 282  XXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQT 341
                         + +Q I      K E++ K + E++   +++++ +  ++ N QI+Q 
Sbjct: 1195 LLSSNQG------VEEQKIWV-IHYKKEVD-KLNKEVSLSQQISQQYQSQKNDNDQIKQE 1246

Query: 342  NKELENKLATMGTESKAVSSPSKKGSPLISRKSGR-NTASKMKSPWSQLSSETLN-QDTD 399
            N++L NKL  +  + + + S  K+       KS    + S+ ++   +L    L  Q   
Sbjct: 1247 NQKL-NKL--LDNQQQQIVSLKKEVEQHKQEKSKLVESISQQENRILELEEIKLQKQILQ 1303

Query: 400  KKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQH 459
             K++  E+ K +  +Q   +    +   + +              K+ ++AQ Q +++  
Sbjct: 1304 GKVS--ELQKSQQEVQQKYQQAQAQLQSVQDDLQHSKKEIQETKQKNKVLAQQQ-QNEMS 1360

Query: 460  MEGPSLIHVGTNTEDVNEIAKVQEQLKQ-ELNDEIKDVNVKDLIEKLKSAEEQITQLNDE 518
                 +I +    E++ +  K+Q ++K+ E     +++ ++   EKLK   +Q+    DE
Sbjct: 1361 KFNQEIIAI---QEELEQSRKIQMEIKKSEQEQREQNMQIRQNYEKLKLENQQLNNQLDE 1417

Query: 519  I---------DAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQ 569
            I         +   K+    K + ++K K  Q    N + ++   +  +  T ++   S 
Sbjct: 1418 IQQDMKYEKEEVLKKDETIYKLSDQVKYKTQQLEAQN-TLINQVEQNKLSQTNQILQQSN 1476

Query: 570  KVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIE-MENLAETRLKAISLLESQKFDLVQ 628
            ++  L +E  +L+  L   D+    +S+ YK+ +E +    E + K +   + Q   L Q
Sbjct: 1477 QLTNLSKELFSLKQQLQINDA----QSESYKREVERLRRELEFQEKQVEDYKQQTKKLSQ 1532

Query: 629  ELHILQQKYDEVEDKLADISQLQS--DQVCSEIKSVHLEEQIDALSASKKELALVIENLK 686
            +L   ++K+ + + K+ + S+L S  D   S IK V  + Q    S+  K    + +   
Sbjct: 1533 QLDF-EKKHSQ-KQKIYEASELLSKIDNTLSPIKGV--KGQTLYGSSDSKTQKRIFQQKT 1588

Query: 687  LDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSK 746
              +E  YG     +N     M       Q+ +   ++  K S E+  +++ ++   EQ+ 
Sbjct: 1589 PQRE--YG----FQNSNSASMLNASFNSQDQLAKENRKLKQSLEQKMKIIEQL---EQAL 1639

Query: 747  IQTQFGIDAKIQERDLYIENIESELSKYKSRICRLE-ESIAVMEDRRYSLERKADQLGSY 805
            +Q++  +    ++ + + +  E E+ + K +  RLE E   ++ +R Y  ++ + Q    
Sbjct: 1640 LQSEQTLKEVHEKANQFCQQQEDEIKQIKDQYSRLEQEHNTILAEREYENQQISKQ---- 1695

Query: 806  LQEKQKAYSEYTIQEDELV 824
               K++A  +  I +DE++
Sbjct: 1696 ---KEQALFKVQILQDEVL 1711


>UniRef50_Q9VJE5 Cluster: Restin homolog; n=4; Drosophila
            melanogaster|Rep: Restin homolog - Drosophila
            melanogaster (Fruit fly)
          Length = 1690

 Score =  140 bits (339), Expect = 3e-31
 Identities = 249/1188 (20%), Positives = 520/1188 (43%), Gaps = 128/1188 (10%)

Query: 483  EQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKS---NHKLKLKQ 539
            + L +E    ++ + V+  +++ + A+ Q  QL   I+     +++++S   N + K ++
Sbjct: 370  QDLLREKQQHVEKLMVERDLDR-EDAQNQALQLQKNINELKARIVELESALDNERKKTEE 428

Query: 540  MQKTIDNFSKVSDS-NKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDV 598
            +Q +ID      D  N +     E++H L  K+ +L     +LQ  ++  D    + SD 
Sbjct: 429  LQCSIDEAQFCGDELNAQSQVYKEKIHDLESKITKLVSATPSLQ-SILPPD----LPSDD 483

Query: 599  YKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSE 658
                 E+  L E        +ES+  + ++E   L++    + +++A    LQS+ V  +
Sbjct: 484  GALQEEIAKLQEKMTIQQKEVESRIAEQLEEEQRLRENVKYLNEQIAT---LQSELVSKD 540

Query: 659  IKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENM 718
                   E ++  S S+  +  +   L+L KE+     K  +  + +   KL     E +
Sbjct: 541  -------EALEKFSLSECGIENLRRELELLKEE---NEKQAQEAQAEFTRKLAEKSVEVL 590

Query: 719  DLTDKLEKMSAEKISELLAKINHEEQSKI-QTQFGI-DAKIQERDLYIENIESELSKYKS 776
             L+ +L+ + A   S    ++N  ++ +I QT+  + D +I+E +  ++ + ++L+  K+
Sbjct: 591  RLSSELQNLKATSDSLESERVNKTDECEILQTEVRMRDEQIRELNQQLDEVTTQLNVQKA 650

Query: 777  RICRLEESIAVM----EDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMD 832
                L++ + +     E++   LE+   +L    ++  K  ++   Q ++ ++ L  L +
Sbjct: 651  DSSALDDMLRLQKEGTEEKSTLLEKTEKELVQSKEQAAKTLNDKE-QLEKQISDLKQLAE 709

Query: 833  HDRVV----EKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTD- 887
             +++V    E  + +I+ E + ++++  +   E ++ Q   S+ + H   +  +  + D 
Sbjct: 710  QEKLVREMTENAINQIQLEKESIEQQLALKQNELEDFQKKQSESEVHLQEIKAQNTQKDF 769

Query: 888  -LAESEST--KYQTQLRD-------LESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIE 937
             L ES  +  K Q QL         L++ L+ +  E +T+I +K++E++ L+ + + + E
Sbjct: 770  ELVESGESLKKLQQQLEQKTLGHEKLQAALEELKKEKETIIKEKEQELQQLQSK-SAESE 828

Query: 938  SAIRDKKVLNEKYEKNIEYVTQLEAQ-LQEYKNNIENLNMNVEELNKMNLELIDKHVQKQ 996
            SA++  +V  E+ ++      +  ++ + +  + I  L    EE  +  L+    +++ +
Sbjct: 829  SALKVVQVQLEQLQQQAAASGEEGSKTVAKLHDEISQLKSQAEE-TQSELKSTQSNLEAK 887

Query: 997  QTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTK 1056
              Q          E  K   LL    E+I  L  ++   Q +  S  +D ESK    T +
Sbjct: 888  SKQLEAANGSLEEEAKKSGHLL----EQITKLKSEVGETQAALSSCHTDVESK----TKQ 939

Query: 1057 LENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIK-ELK---------ETKLTFEMNI 1106
            LE     +++V+K+  +S+    +LQ  V+E  D +  EL+          TKL+   + 
Sbjct: 940  LEAANAALEKVNKEYAESRAEASDLQDKVKEITDTLHAELQAERSSSSALHTKLSKFSDE 999

Query: 1107 PKTEGMIISSTIEPMSDDA-------NNVDXXXXXXXXXXXXLKVQ---EEEEFIQERSV 1156
              T    ++S  +  S +          +             LK +   +E+ F +    
Sbjct: 1000 IATGHKELTSKADAWSQEMLQKEKELQELRQQLQDSQDSQTKLKAEGERKEKSFEESIKN 1059

Query: 1157 LQEQSAKLNTELQECYT------KIIQ--LETLNTELTGHDVVNQE---QINQLKSKLEQ 1205
            LQE+  K  TE  E  T      K +Q  LE  N EL   + +  E   +I  LK+ +E 
Sbjct: 1060 LQEEVTKAKTENLELSTGTQTTIKDLQERLEITNAELQHKEKMASEDAQKIADLKTLVEA 1119

Query: 1206 LNTENDNLLSTVAELRSSISSAVDQRG-----FEI----AELWKQHLAQREADFQKTEHE 1256
            +   N N+ +T AEL + +     ++      FE+    A++  + L ++    ++   E
Sbjct: 1120 IQVANANISATNAELSTVLEVLQAEKSETNHIFELFEMEADMNSERLIEKVTGIKEELKE 1179

Query: 1257 LRVQLSAFESKYEQLLDSVQSSTQEETN----KIVTMEQVTSLQNKLQD-------KEEH 1305
              +QL   + K+E+L + ++ + Q E         + E++T +Q  LQ+       KEE 
Sbjct: 1180 THLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEEL 1239

Query: 1306 LRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQ 1365
            ++NL+EK  +  + IE   +++ +  V                   L    +  KQ+QE+
Sbjct: 1240 VQNLEEKVRESSSIIEAQNTKLNESNVQL----ENKTSCLKETQDQLLESQKKEKQLQEE 1295

Query: 1366 SILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDS------EIYQK 1419
            +   ++ E  Q+++++             V   E K+   T QL+ + +      E+  K
Sbjct: 1296 A-AKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQATNKELQELLVK 1354

Query: 1420 THEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKE 1479
            + E    L   +       QQL +    +++   +KE+ L  L+ K+ E+    E+ QK+
Sbjct: 1355 SQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESNTVLES-QKK 1413

Query: 1480 SEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDE 1539
            S  E    +E+   K     +L ++ ++L + L +      E+Q +L+ +++ +   N+ 
Sbjct: 1414 SHNEIQDKLEQAQQK---ERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLLEKGNEF 1470

Query: 1540 ITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRA 1587
             T L     A   K+   +  A+  K    EQL N +  EL  A+ +A
Sbjct: 1471 DTQL-----AEYQKVIDEMDDAASVKSALLEQLQNRV-AELETALRQA 1512



 Score =  126 bits (303), Expect = 7e-27
 Identities = 233/1205 (19%), Positives = 497/1205 (41%), Gaps = 74/1205 (6%)

Query: 146  HLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXX 205
            H+   + E+D      Q +   ++  I +L+ +I E +  ++ + K T            
Sbjct: 379  HVEKLMVERDLDREDAQNQALQLQKNINELKARIVELESALDNERKKTEELQCSIDEAQF 438

Query: 206  XXXXXXEDT---KQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEA 262
                    +   K+++  ++     + +     +  L  D+ S D  +   EE  KL E 
Sbjct: 439  CGDELNAQSQVYKEKIHDLESKITKLVSATPSLQSILPPDLPSDDGALQ--EEIAKLQEK 496

Query: 263  ARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMT 322
               +     S++A++LE+              +A  +++     K E  EK SL    + 
Sbjct: 497  MTIQQKEVESRIAEQLEEEQRLRENVKYLNEQIA--TLQSELVSKDEALEKFSLSECGIE 554

Query: 323  ELTKKIELLEHLN-CQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASK 381
             L +++ELL+  N  Q ++   E   KLA    E   +SS       L + K+   T+  
Sbjct: 555  NLRRELELLKEENEKQAQEAQAEFTRKLAEKSVEVLRLSSE------LQNLKA---TSDS 605

Query: 382  MKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXX 441
            ++S     + E     T+ ++   +I +L   +  +   L  ++   S  D         
Sbjct: 606  LESERVNKTDECEILQTEVRMRDEQIRELNQQLDEVTTQLNVQKADSSALDDMLRLQKEG 665

Query: 442  XXGKDTLIAQLQLEHQQHME--GPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVK 499
               K TL+ + + E  Q  E    +L       + ++++ ++ EQ  ++L  E+ +  + 
Sbjct: 666  TEEKSTLLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQ--EKLVREMTENAIN 723

Query: 500  DLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVR 559
             +  + +S E+Q+    +E++   K   + +S   L+  + Q T  +F  V +S + + +
Sbjct: 724  QIQLEKESIEQQLALKQNELEDFQKK--QSESEVHLQEIKAQNTQKDFELV-ESGESLKK 780

Query: 560  LTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLL 619
            L ++L    QK   L  EK    L  +  +   +I+ +  +++ ++++ +     A+ ++
Sbjct: 781  LQQQLE---QKT--LGHEKLQAALEELKKEKETIIK-EKEQELQQLQSKSAESESALKVV 834

Query: 620  ESQKFDLVQELHILQQKYDEVEDKLAD-ISQL--QSDQVCSEIKSVHLEEQIDALSASKK 676
            + Q   L Q+     ++  +   KL D ISQL  Q+++  SE+KS         L A  K
Sbjct: 835  QVQLEQLQQQAAASGEEGSKTVAKLHDEISQLKSQAEETQSELKSTQSN-----LEAKSK 889

Query: 677  ELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELL 736
            +L     +L+ + ++    ++ +   K ++          + D+  K +++ A   +  L
Sbjct: 890  QLEAANGSLEEEAKKSGHLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAA--L 947

Query: 737  AKINHEEQSKIQTQFGIDAKIQE-RDLYIENIESELSKYKSRICRLEESIAVMEDRRYSL 795
             K+N E          +  K++E  D     +++E S   +   +L +    +      L
Sbjct: 948  EKVNKEYAESRAEASDLQDKVKEITDTLHAELQAERSSSSALHTKLSKFSDEIATGHKEL 1007

Query: 796  ERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLE-IEHENKELQKK 854
              KAD     + +K+K   E   Q  +  +    L       EK   E I++  +E+ K 
Sbjct: 1008 TSKADAWSQEMLQKEKELQELRQQLQDSQDSQTKLKAEGERKEKSFEESIKNLQEEVTKA 1067

Query: 855  NQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEH 914
                LE +   Q ++ D+Q+       +    +   SE  +    L+ L   ++      
Sbjct: 1068 KTENLELSTGTQTTIKDLQERLEITNAELQHKEKMASEDAQKIADLKTLVEAIQVANANI 1127

Query: 915  QTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENL 974
                 +    +E L+ E +         +   +   E+ IE VT ++ +L+E    ++  
Sbjct: 1128 SATNAELSTVLEVLQAEKSETNHIFELFEMEADMNSERLIEKVTGIKEELKETHLQLDER 1187

Query: 975  NMNVEELNKM--NLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKI 1032
                EEL +     +  ++ +Q++   S +   +    + +L   +KQK+E +  L +K+
Sbjct: 1188 QKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKV 1247

Query: 1033 NNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQI 1092
              +     S++    +KL +   +LEN    ++    QLL+S++  ++LQ    +   ++
Sbjct: 1248 RESS----SIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGEL 1303

Query: 1093 KELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXL-KVQEEEEFI 1151
            ++++E     + ++ K E  ++    E +    + +D            L K QE E  +
Sbjct: 1304 QQVQEANGDIKDSLVKVE-ELVKVLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNL 1362

Query: 1152 QERSVL----QEQSAKLNTELQECY-TKIIQLETLNTELTGHDVVNQEQ---INQLKSKL 1203
            Q  S+      +Q  + N EL+E    K   L+ L  +L   + V + Q    N+++ KL
Sbjct: 1363 QGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKL 1422

Query: 1204 EQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSA 1263
            EQ   +   L    ++L   +S  + Q   E+    ++ L Q++   +K  +E   QL  
Sbjct: 1423 EQAQQKERTLQEETSKLAEQLSQ-LKQANEEL----QKSLQQKQLLLEK-GNEFDTQL-- 1474

Query: 1264 FESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEIL 1323
              ++Y++++D +  +    + K   +EQ   LQN++ + E  LR   +       + + L
Sbjct: 1475 --AEYQKVIDEMDDAA---SVKSALLEQ---LQNRVAELETALRQANDAQKTAYLETKEL 1526

Query: 1324 RSEIE 1328
            R ++E
Sbjct: 1527 RRQLE 1531



 Score =  112 bits (270), Expect = 7e-23
 Identities = 207/1006 (20%), Positives = 407/1006 (40%), Gaps = 90/1006 (8%)

Query: 51   QIKFERAQK-CLENAALVSKRIKEHRKATAELLGRPFVPGISESLANTLKQKEILMEKIK 109
            Q+  ++A    L++   + K   E +    E   +  V    E  A TL  KE L ++I 
Sbjct: 644  QLNVQKADSSALDDMLRLQKEGTEEKSTLLEKTEKELVQS-KEQAAKTLNDKEQLEKQIS 702

Query: 110  QYKELSKRSSTT--IVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNALSVLQVKMKI 167
              K+L+++      +                 QL    +     ++K +   V   ++K 
Sbjct: 703  DLKQLAEQEKLVREMTENAINQIQLEKESIEQQLALKQNELEDFQKKQSESEVHLQEIKA 762

Query: 168  METT----ILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQE 223
              T     +++  E + +  Q +E K                      ++ +Q++ ++Q 
Sbjct: 763  QNTQKDFELVESGESLKKLQQQLEQKTLGHEKLQAALEELKKEKETIIKEKEQELQQLQS 822

Query: 224  NFIAMEAEWK-------DEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQ 276
                 E+  K         +Q+     E     ++ L +    L++   E   E      
Sbjct: 823  KSAESESALKVVQVQLEQLQQQAAASGEEGSKTVAKLHDEISQLKSQAEETQSELKSTQS 882

Query: 277  ELEQXXXXXXXXXXXXXXLAKQS---IEPSCEEKTEIEEKGSLEIANMTELTKKIELLEH 333
             LE                AK+S   +E   + K+E+ E  +   +  T++  K + LE 
Sbjct: 883  NLEAKSKQLEAANGSLEEEAKKSGHLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEA 942

Query: 334  LNCQIRQTNKEL-ENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSE 392
             N  + + NKE  E++      + K         + L   ++ R+++S + +  S+ S E
Sbjct: 943  ANAALEKVNKEYAESRAEASDLQDKVKEITDTLHAEL---QAERSSSSALHTKLSKFSDE 999

Query: 393  --TLNQDTDKKIN--KNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTL 448
              T +++   K +    E+ + E  +Q L + L D +     +              +  
Sbjct: 1000 IATGHKELTSKADAWSQEMLQKEKELQELRQQLQDSQ---DSQTKLKAEGERKEKSFEES 1056

Query: 449  IAQLQLEHQQHMEGPSLIHVGTNT--EDVNEI-----AKVQEQLKQELNDEIKDVNVKDL 501
            I  LQ E  +       +  GT T  +D+ E      A++Q + K    D  K  ++K L
Sbjct: 1057 IKNLQEEVTKAKTENLELSTGTQTTIKDLQERLEITNAELQHKEKMASEDAQKIADLKTL 1116

Query: 502  IEKLKSAEEQITQLNDEIDAANKNMIKVKS--NHKLKLKQMQKTIDN---FSKVSDSNKE 556
            +E ++ A   I+  N E+    + +   KS  NH  +L +M+  +++     KV+   +E
Sbjct: 1117 VEAIQVANANISATNAELSTVLEVLQAEKSETNHIFELFEMEADMNSERLIEKVTGIKEE 1176

Query: 557  IVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAI 616
            +     +L    +K  ELEE+    Q       S + ++ +        E L E +    
Sbjct: 1177 LKETHLQLDERQKKFEELEEKLKQAQ------QSEQKLQQE---SQTSKEKLTEIQQSLQ 1227

Query: 617  SLLES--QKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSAS 674
             L +S  QK +LVQ L    ++   + +  A  ++L    V  E K+  L+E  D L  S
Sbjct: 1228 ELQDSVKQKEELVQNLEEKVRESSSIIE--AQNTKLNESNVQLENKTSCLKETQDQLLES 1285

Query: 675  -KKELALVIENLKLDKE-----QLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMS 728
             KKE  L  E  KL  E     +  G IKD     E+++  L+  +Q      D  +  +
Sbjct: 1286 QKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQATN 1345

Query: 729  AEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVM 788
             E + ELL K    E +       +  K+Q+    +E    EL   K  +C+ E  +   
Sbjct: 1346 KE-LQELLVKSQENEGNLQGESLAVTEKLQQ----LEQANGEL---KEALCQKENGLK-- 1395

Query: 789  EDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHEN 848
                  L+ K D+  + L+ ++K+++E   + ++   +   L +    + +QL +++  N
Sbjct: 1396 -----ELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQAN 1450

Query: 849  KELQK---KNQILLEENQNLQISLSDMQQHYNALVEKAN-RTDLAESESTKYQTQLRDLE 904
            +ELQK   + Q+LLE+       L++ Q+  + + + A+ ++ L E    + Q ++ +LE
Sbjct: 1451 EELQKSLQQKQLLLEKGNEFDTQLAEYQKVIDEMDDAASVKSALLE----QLQNRVAELE 1506

Query: 905  SNLKRITHEHQTLIVQKK---KEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLE 961
            + L++     +T  ++ K   +++E LE+E + ++ S        + +  K  E V  L+
Sbjct: 1507 TALRQANDAQKTAYLETKELRRQLESLELEKSREVLSLKAQMNGASSRSGKGDE-VESLD 1565

Query: 962  AQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQY 1007
             +    K N   LN  + ++ + N + +   VQ  +T   D+T+ +
Sbjct: 1566 IETSLAKINF--LNSIIADMQQKN-DALKAKVQTLETLPMDFTKPH 1608



 Score = 90.6 bits (215), Expect = 3e-16
 Identities = 150/813 (18%), Positives = 325/813 (39%), Gaps = 72/813 (8%)

Query: 748  QTQFGIDAKIQERDLYIEN--IESELSKY--KSRICRLEESIAVMEDRRYSLERKADQLG 803
            ++QF +   ++E+  ++E   +E +L +   +++  +L+++I  ++ R   LE   D   
Sbjct: 364  KSQFSMQDLLREKQQHVEKLMVERDLDREDAQNQALQLQKNINELKARIVELESALDNER 423

Query: 804  SYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQK-KNQILLEEN 862
               +E Q +  E     DEL  +  V  +    +E ++ ++      LQ      L  ++
Sbjct: 424  KKTEELQCSIDEAQFCGDELNAQSQVYKEKIHDLESKITKLVSATPSLQSILPPDLPSDD 483

Query: 863  QNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKK 922
              LQ  ++ +Q+    + +K   + +AE    + + +LR+    L       Q+ +V K 
Sbjct: 484  GALQEEIAKLQEKMT-IQQKEVESRIAEQ--LEEEQRLRENVKYLNEQIATLQSELVSKD 540

Query: 923  KEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELN 982
            + +E   +     IE+  R+ ++L E+ EK  +   Q E   +  + ++E L ++ E   
Sbjct: 541  EALEKFSLS-ECGIENLRRELELLKEENEKQAQEA-QAEFTRKLAEKSVEVLRLSSE--- 595

Query: 983  KMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSM 1042
              NL+     ++ ++    D  E    E+       + +DE+I  LNQ+++         
Sbjct: 596  LQNLKATSDSLESERVNKTDECEILQTEV-------RMRDEQIRELNQQLDEVTTQLNVQ 648

Query: 1043 VSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTF 1102
             +D  +       + E  EE+   + K   +  Q  E+    + +++   K++ + K   
Sbjct: 649  KADSSALDDMLRLQKEGTEEKSTLLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLA 708

Query: 1103 EMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSA 1162
            E              +  M+++A N              LK  E E+F       Q++ +
Sbjct: 709  EQE----------KLVREMTENAINQIQLEKESIEQQLALKQNELEDF-------QKKQS 751

Query: 1163 KLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRS 1222
            +    LQE       ++  NT+     V + E + +L+ +LEQ    ++ L + + EL+ 
Sbjct: 752  ESEVHLQE-------IKAQNTQKDFELVESGESLKKLQQQLEQKTLGHEKLQAALEELKK 804

Query: 1223 SISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEE 1282
               + + ++  E+     Q L  + A+ +     ++VQL       EQL     +S +E 
Sbjct: 805  EKETIIKEKEQEL-----QQLQSKSAESESALKVVQVQL-------EQLQQQAAASGEEG 852

Query: 1283 TNKIVTM-EQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXX 1341
            +  +  + ++++ L+++ ++ +  L++ Q        Q+E     +E+E           
Sbjct: 853  SKTVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKK-SGHLLEQ 911

Query: 1342 XXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAK 1401
                     + +    S     E     +   NA L+K +              +D + K
Sbjct: 912  ITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALEKVNKEYAESRA----EASDLQDK 967

Query: 1402 VLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAI 1461
            V E+T  L  +       +      L++ +DE     ++L            +KE EL  
Sbjct: 968  VKEITDTLHAELQAERSSSSALHTKLSKFSDEIATGHKELTSKADAWSQEMLQKEKELQE 1027

Query: 1462 LRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNE 1521
            LR ++ ++ +    ++ E E  + K  EE         S+     E+ KA  E +  +  
Sbjct: 1028 LRQQLQDSQDSQTKLKAEGE-RKEKSFEE---------SIKNLQEEVTKAKTENLELSTG 1077

Query: 1522 MQTALENQEIEIVTLNDEITNLQNMVRASSSKI 1554
             QT +++ +  +   N E+ + + M    + KI
Sbjct: 1078 TQTTIKDLQERLEITNAELQHKEKMASEDAQKI 1110



 Score = 64.9 bits (151), Expect = 2e-08
 Identities = 131/711 (18%), Positives = 287/711 (40%), Gaps = 44/711 (6%)

Query: 878  ALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIE 937
            +L   + +T L+ + S +  T +  + S     T   +    Q+K       I    + +
Sbjct: 307  SLSPSSKKTRLSRTGSRESLTSIGTMNSIATTATSRMRMNAQQRKSSTPVKPILATPKSQ 366

Query: 938  SAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLEL---IDKHVQ 994
             +++D  +L EK +   + + + +   ++ +N    L  N+ EL    +EL   +D   +
Sbjct: 367  FSMQD--LLREKQQHVEKLMVERDLDREDAQNQALQLQKNINELKARIVELESALDNERK 424

Query: 995  K-QQTQ-SPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVS-DYESKLA 1051
            K ++ Q S D  +   +E+N  + + K+K  ++ +   K+ +A  S  S++  D  S   
Sbjct: 425  KTEELQCSIDEAQFCGDELNAQSQVYKEKIHDLESKITKLVSATPSLQSILPPDLPSDDG 484

Query: 1052 QFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEG 1111
                ++  ++E+M    K++        E +  +RE    +K L E   T +  +   + 
Sbjct: 485  ALQEEIAKLQEKMTIQQKEVESRIAEQLEEEQRLREN---VKYLNEQIATLQSELVSKDE 541

Query: 1112 MIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQEC 1171
             +   ++     +  N+                + + EF ++ +    +  +L++ELQ  
Sbjct: 542  ALEKFSLSECGIE--NLRRELELLKEENEKQAQEAQAEFTRKLAEKSVEVLRLSSELQNL 599

Query: 1172 YTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQR 1231
                  LE+     T    + Q ++     ++ +LN + D + +T   ++ + SSA+D  
Sbjct: 600  KATSDSLESERVNKTDECEILQTEVRMRDEQIRELNQQLDEV-TTQLNVQKADSSALD-- 656

Query: 1232 GFEIAELWKQHLAQREADFQKTEHELRVQ--------LSAFESKYEQLLDSVQSSTQEET 1283
              ++  L K+   ++    +KTE EL VQ        L+  E   +Q+ D  Q + QE+ 
Sbjct: 657  --DMLRLQKEGTEEKSTLLEKTEKEL-VQSKEQAAKTLNDKEQLEKQISDLKQLAEQEKL 713

Query: 1284 NKIVTMEQVTSLQNKLQDKEEHL---RNLQEKYADVINQIEILRSEIEDEKVAFXXXXXX 1340
             + +T   +  +Q + +  E+ L   +N  E +    ++ E+   EI+ +          
Sbjct: 714  VREMTENAINQIQLEKESIEQQLALKQNELEDFQKKQSESEVHLQEIKAQNTQKDFELVE 773

Query: 1341 XXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEA 1400
                       L  +   ++++Q  ++  + +E   + K                +++  
Sbjct: 774  SGESLKKLQQQLEQKTLGHEKLQA-ALEELKKEKETIIKEKEQELQQLQSKSAE-SESAL 831

Query: 1401 KVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYE---KES 1457
            KV+++  QLE    +      E + T+ + +DE   ++ Q  E +  ++        K  
Sbjct: 832  KVVQV--QLEQLQQQAAASGEEGSKTVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSK 889

Query: 1458 ELAILRLKMHENANH----YETMQK-ESEIERVKLIEELNVKITESVSLNKQVAELNKAL 1512
            +L      + E A       E + K +SE+   +    L+   T+  S  KQ+   N AL
Sbjct: 890  QLEAANGSLEEEAKKSGHLLEQITKLKSEVGETQAA--LSSCHTDVESKTKQLEAANAAL 947

Query: 1513 EEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASD 1563
            E+   +  E +    + + ++  + D +       R+SSS +   +S  SD
Sbjct: 948  EKVNKEYAESRAEASDLQDKVKEITDTLHAELQAERSSSSALHTKLSKFSD 998



 Score = 40.7 bits (91), Expect = 0.32
 Identities = 59/334 (17%), Positives = 135/334 (40%), Gaps = 20/334 (5%)

Query: 49   ERQIKFERAQKCLENAALVSKRIKEHRKATAELLGRPFVPGISESLANTLKQKEILM--- 105
            ERQ KFE  ++ L+ A    +++++  + + E L    +    + L +++KQKE L+   
Sbjct: 1186 ERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTE--IQQSLQELQDSVKQKEELVQNL 1243

Query: 106  -EKIKQYKELSKRSSTTIVRXXXXXXXXXX--XXXXXQLGDVTHLSNTIKEKDNALSVLQ 162
             EK+++   + +  +T +                   QL +       ++E+   LS   
Sbjct: 1244 EEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGEL 1303

Query: 163  VKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQ 222
             +++     I D   K+ E  +++E K +A T                   +++    +Q
Sbjct: 1304 QQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQ 1363

Query: 223  ENFIAMEAEWKDEKQ---RLLKDIESKDVRI----SSLEEANKLLEAAR-----FEISLE 270
               +A+  + +  +Q    L + +  K+  +      L+E+N +LE+ +      +  LE
Sbjct: 1364 GESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLE 1423

Query: 271  HSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIEL 330
             ++  +   Q               A + ++ S ++K  + EKG+     + E  K I+ 
Sbjct: 1424 QAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLLEKGNEFDTQLAEYQKVIDE 1483

Query: 331  LEHLNCQIRQTNKELENKLATMGTESKAVSSPSK 364
            ++          ++L+N++A + T  +  +   K
Sbjct: 1484 MDDAASVKSALLEQLQNRVAELETALRQANDAQK 1517


>UniRef50_A0D7Y2 Cluster: Chromosome undetermined scaffold_40, whole
            genome shotgun sequence; n=1; Paramecium tetraurelia|Rep:
            Chromosome undetermined scaffold_40, whole genome shotgun
            sequence - Paramecium tetraurelia
          Length = 1498

 Score =  140 bits (338), Expect = 4e-31
 Identities = 238/1228 (19%), Positives = 541/1228 (44%), Gaps = 98/1228 (7%)

Query: 387  SQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKD 446
            SQ   +  NQ+   + + N+  +LE  I+SL  ++  K   +S+ +            + 
Sbjct: 2    SQTPEQNRNQEVWLRNSLNKNNRLEFEIKSLQNEVKTKNQQLSQLEMDYKGQVNQLQQQI 61

Query: 447  TLIAQLQLEHQQHMEG-PSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDL---- 501
             +   LQL+ QQ  +G            D N   K Q +  QE N+  KD + ++L    
Sbjct: 62   QINQSLQLQIQQISQGNTDQKKAIEQLTDQNNQLKNQLKQVQETNNIEKDQSKQNLERAN 121

Query: 502  --IEKLKSAEEQITQLNDEIDAANKNMI-KVKSNHKLKLKQMQKTIDNFSKVSDSNKEIV 558
              I+KLK+   Q+ + ND +       I ++ +N K  ++++Q+ I    ++S ++K I 
Sbjct: 122  TDIQKLKNEILQLQRNNDSLQQQKTYQISQLDTNSKKVIEELQEQIRKM-QLSATSK-IE 179

Query: 559  RLTEEL----HHLSQKVAELEEEKGNLQLHLVDYD------SGRMIESDVYKKMIEM--- 605
             LT EL      L + + E+  +K  L     +Y+      S ++I++   ++  +    
Sbjct: 180  SLTSELSLKNDQLDKLMKEINIKKNELYQSTANYEAVNATKSQQLIQAQQIQQKCQQDFN 239

Query: 606  ENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLE 665
            + LA+ +L+A   +   + ++ Q+  I+++   ++  K  +I   +++Q   +I + + +
Sbjct: 240  DKLAQFQLQAQMKITQMEQEIGQKNTIIEKANQDLAKKAQEIK--ENNQNFEQINNQNQK 297

Query: 666  E-QIDALSASKKELALVIENLKLDKEQLYGTIK-DLENDKEDIMNKLQNYIQENMDLTDK 723
            + Q   +   K +LA+  EN + D+++  G +K  ++N ++D+  + Q+  Q    L ++
Sbjct: 298  KLQQMMIQVQKLQLAIESENTQYDRKK--GDLKVQIDNLEKDLNMQQQSSNQYTQKLNNE 355

Query: 724  LEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEE 783
            + ++  + + +L  +++ + +S   +Q   DA+I++ +L + + + E+     ++ + E 
Sbjct: 356  INQLKNQNL-DLQRQLSEKHKSLCLSQTESDAQIKQLNLQVASFQKEIQLKNQQLQQAES 414

Query: 784  SIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLE 843
             +  M+  +    ++ DQ+     +++K   E  IQ D+L N     M   +V+    L 
Sbjct: 415  QLLEMKVLKV---QEIDQMKLKFDQREK---ELLIQNDQLNNNNK--MQSQKVI---TLS 463

Query: 844  IEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDL 903
             E  N+++++ +Q   E+  NL  S    +  Y   + +  +  LA+ + T  + ++  +
Sbjct: 464  NEELNRQIKQVDQFWTEKYNNL--SKQTKEDIYQ--LTQQYQMQLAQMDQTN-KEKIYVI 518

Query: 904  ESNLKRITHEHQTLI-VQ---KKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQ 959
            E N  +  +  + L  VQ     K+I DL+ E    I      K  LNE  +K   + ++
Sbjct: 519  EQNHNQFLNSQKELFNVQLSLLNKQILDLQKERENSIIQLDLMKVKLNELQDKTQNFNSR 578

Query: 960  LEAQLQEYKNNIENLNMNVEE-LNKMNLELI--DKHVQKQQTQSPDYTEQYINEINKLNA 1016
             + + +  +N +  L  + EE LN +N + +   K +   QT+     +QY N + +   
Sbjct: 579  DQRKDELMQNQMATLKNSKEELLNVINQQNLAHKKEIYNLQTKIDQLQQQYDNSVREGKQ 638

Query: 1017 LLKQKDEEIIALNQKIN---NAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLD 1073
            + +Q     +   Q  N         ++  +D +S++ +  ++L  +E   ++V  +L  
Sbjct: 639  IKEQLKLSQLEAQQVYNLSHQKNKESLNAQADKDSEIIKLQSELSRVETLYKQVVLELKI 698

Query: 1074 SKQHNEELQIL----VREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVD 1129
              +   +LQ++    ++E+D +I   K   L  +  + + +  I  + +E    +AN   
Sbjct: 699  INEQKNDLQVIDDFQLKEKDIEIGNQKSYILELKQKLQQLQKRI--NELELQLQNANK-- 754

Query: 1130 XXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHD 1189
                        ++   +   IQ+R + QE+  + + EL E   + ++++T N  L    
Sbjct: 755  KLGQKDQEAKKEIENLNQRITIQKRQI-QEERERCD-ELAE--AQEMEVQTWNERLKEQQ 810

Query: 1190 VVNQEQINQLKSKLEQLNTENDNLLSTVAELRSS---ISSAVDQRGFEIAELWKQHLAQR 1246
             +N++ I QL  +L+Q  ++N  L++ +  L+     +++   Q   +  E  KQ    +
Sbjct: 811  KLNEDLIIQL-MRLQQQTSQNSGLINELQNLKQQFEIVTNQYKQLQEDAEEATKQKSMVK 869

Query: 1247 EADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETN-KIVTME-QVTSLQNKLQDKEE 1304
                Q  ++    Q+       +QL D  QS+  ++    I+    Q+ +L + L  K  
Sbjct: 870  NVQIQMLQNHYNKQMDVLT---QQLEDMKQSNLNQKLEFPIMDFNVQIIALNDLLVKKNA 926

Query: 1305 HLRNLQ-EKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTEN-QSYKQM 1362
             +  L+ +    ++ +  ++  + E  +                     R +N Q   + 
Sbjct: 927  EINQLKSQTQQKLLEKDSVIDQQREYAQQLLSEFEKLQVQLMDQHEFQERADNLQMINEE 986

Query: 1363 QEQSILNINEENAQLKKSSXXXXXXXXXXXXR---VNDAEAKVLELTHQLELKDSEIYQK 1419
            ++ SI+ + EE A+LK+ +                + D +  + +L  +L+ K   I  K
Sbjct: 987  KDNSIIYLKEEIAKLKQENKLIKGKLDLKEQSMVVIQDQQQLIKQLKIELQNKQKNIQPK 1046

Query: 1420 THEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANH----YET 1475
                +   T ++     + ++     +   ++ +  ES+       + EN N+    +  
Sbjct: 1047 QIAVSHQQTMKS-SIHRMSKRSESSRQEKSEVDWNGESQF------LMENGNNKLPCFHQ 1099

Query: 1476 MQKESEIERVKLIEELNVKITE-SVSLNKQVAELN---KALEEEVAKTNEMQTALENQEI 1531
               ES  +  KLIE++N +I + ++ L  QV  LN   ++L+ ++ +T +    ++N+  
Sbjct: 1100 QSSESFTDN-KLIEKMNSEIVDTNIRLRNQVDLLNQDKQSLQNDLTRTIQSLNQVKNENS 1158

Query: 1532 EIVTLNDEITNLQNMVRASSSKIQKHVS 1559
            E++     +       + +  K+++ ++
Sbjct: 1159 ELILKLQYVQKALESSQQNQEKLEREIN 1186



 Score =  131 bits (317), Expect = 1e-28
 Identities = 251/1367 (18%), Positives = 582/1367 (42%), Gaps = 138/1367 (10%)

Query: 172  ILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAE 231
            I +LQE+I +      +K ++ T                    K ++ +   N+ A+ A 
Sbjct: 160  IEELQEQIRKMQLSATSKIESLTSELSLKNDQLDKLMKEINIKKNELYQSTANYEAVNAT 219

Query: 232  WKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXX 291
               + Q+L   I+++ ++    ++ N  L   + +  ++ +++ QE+ Q           
Sbjct: 220  ---KSQQL---IQAQQIQQKCQQDFNDKLAQFQLQAQMKITQMEQEIGQKNTIIEKANQD 273

Query: 292  XXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIEL-LEHLNCQIRQTNKEL----E 346
                A Q I+ + +   +I  +   ++  M    +K++L +E  N Q  +   +L    +
Sbjct: 274  LAKKA-QEIKENNQNFEQINNQNQKKLQQMMIQVQKLQLAIESENTQYDRKKGDLKVQID 332

Query: 347  NKLATMGTESKAVSSPSKKGSPLISRKSGRNT--ASKMKSPWSQLSSETLNQDTDKKINK 404
            N    +  + ++ +  ++K +  I++   +N     ++      L       D   K   
Sbjct: 333  NLEKDLNMQQQSSNQYTQKLNNEINQLKNQNLDLQRQLSEKHKSLCLSQTESDAQIKQLN 392

Query: 405  NEIAKLEMVIQSLNKDLVDKEY------VISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQ 458
             ++A  +  IQ  N+ L   E       V+  ++            K+ LI   QL +  
Sbjct: 393  LQVASFQKEIQLKNQQLQQAESQLLEMKVLKVQEIDQMKLKFDQREKELLIQNDQLNNNN 452

Query: 459  HMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDE 518
             M+   +I +  + E++N   K  +Q   E  + +     +D+ +  +  + Q+ Q+   
Sbjct: 453  KMQSQKVITL--SNEELNRQIKQVDQFWTEKYNNLSKQTKEDIYQLTQQYQMQLAQM--- 507

Query: 519  IDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEK 578
             D  NK  I V   +  +    QK + N  ++S  NK+I+ L +E  +   ++  ++ + 
Sbjct: 508  -DQTNKEKIYVIEQNHNQFLNSQKELFNV-QLSLLNKQILDLQKERENSIIQLDLMKVKL 565

Query: 579  GNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYD 638
              LQ    +++S    + ++ +   +M  L  ++ + ++++  Q     +E++ LQ K D
Sbjct: 566  NELQDKTQNFNSRDQRKDELMQN--QMATLKNSKEELLNVINQQNLAHKKEIYNLQTKID 623

Query: 639  EVEDKLADISQLQSDQVCSEIKSVHLE-EQIDALSASKKELALVIENLKLDKEQLYGTIK 697
            +++ +  D S  +  Q+  ++K   LE +Q+  LS  K            +KE L     
Sbjct: 624  QLQQQY-DNSVREGKQIKEQLKLSQLEAQQVYNLSHQK------------NKESL----- 665

Query: 698  DLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKI 757
            + + DK+  + KLQ+ +        ++E +  + + EL  KI +E+++ +Q     D ++
Sbjct: 666  NAQADKDSEIIKLQSELS-------RVETLYKQVVLEL--KIINEQKNDLQVID--DFQL 714

Query: 758  QERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEK-QKAYSEY 816
            +E+D+ I N +S + + K ++ +L++ I  +E +  +  +K  Q     +++ +      
Sbjct: 715  KEKDIEIGNQKSYILELKQKLQQLQKRINELELQLQNANKKLGQKDQEAKKEIENLNQRI 774

Query: 817  TIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHY 876
            TIQ+ ++          D + E Q +E++  N+ L+++ ++    N++L I L  +QQ  
Sbjct: 775  TIQKRQIQEERERC---DELAEAQEMEVQTWNERLKEQQKL----NEDLIIQLMRLQQQT 827

Query: 877  NALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQI 936
            +      N     + +      Q + L+ + +  T +   +   K  +I+ L+  +N Q+
Sbjct: 828  SQNSGLINELQNLKQQFEIVTNQYKQLQEDAEEATKQKSMV---KNVQIQMLQNHYNKQM 884

Query: 937  ESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLN----MNVEELNKMNLELIDKH 992
            +   +    L +  + N+    +LE  + ++   I  LN        E+N++  +   K 
Sbjct: 885  DVLTQQ---LEDMKQSNLNQ--KLEFPIMDFNVQIIALNDLLVKKNAEINQLKSQTQQKL 939

Query: 993  VQKQQT--QSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKL 1050
            ++K     Q  +Y +Q ++E  KL   L  + E      ++ +N Q+    +  + ++ +
Sbjct: 940  LEKDSVIDQQREYAQQLLSEFEKLQVQLMDQHE----FQERADNLQM----INEEKDNSI 991

Query: 1051 AQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTE 1110
                 ++  +++E  ++ K  LD K   E+  +++++Q   IK+LK      + NI   +
Sbjct: 992  IYLKEEIAKLKQE-NKLIKGKLDLK---EQSMVVIQDQQQLIKQLKIELQNKQKNIQPKQ 1047

Query: 1111 GMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQE 1170
              I  S  + M    + +             +    E +F+ E      +    + +  E
Sbjct: 1048 --IAVSHQQTMKSSIHRMSKRSESSRQEKSEVDWNGESQFLMENG--NNKLPCFHQQSSE 1103

Query: 1171 CYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAV-- 1228
             +T    +E +N+E+   ++  + Q++ L    + L  +    + ++ ++++  S  +  
Sbjct: 1104 SFTDNKLIEKMNSEIVDTNIRLRNQVDLLNQDKQSLQNDLTRTIQSLNQVKNENSELILK 1163

Query: 1229 ---DQRGFEIAELWKQHLAQREADFQKTEHELRV-----QLSAFESKYEQLLDSVQSSTQ 1280
                Q+  E ++  ++ L +RE + QK + E+ +     Q+++      Q L+++QSS  
Sbjct: 1164 LQYVQKALESSQQNQEKL-EREIN-QKKKKEINIVSFDDQINSKVKAMNQQLENLQSSKT 1221

Query: 1281 EETNKIVTMEQVTS-LQNKLQDKEEHLRNLQEKYADVINQI------EILRSEIEDEKVA 1333
            ++T  I  ++Q  S L  ++    +  R L+ K   VIN++      +IL  +++ ++  
Sbjct: 1222 QQTQLINQLQQEHSELYQQIDRLNDQNRELR-KNITVINELNQTQEQQILELQMKLKQEQ 1280

Query: 1334 FXXXXXXXXXXXXXXXXDLRT-----ENQSYKQ--------MQEQSILNINEENAQLKKS 1380
                             D  +     ENQ  KQ        +QEQ+ L  N EN Q KK+
Sbjct: 1281 LVTVKQNSEVRVFQLKQDQTSQIVSFENQQLKQQNVELQNKIQEQNQLISNYENQQQKKN 1340

Query: 1381 SXXXXXXX-----XXXXXRVNDAEAKVLELTHQ---LELKDSEIYQKTHEYTITLTQRND 1432
                              ++++ E +  +L  +   + +  +++  +  +Y I + Q   
Sbjct: 1341 GLEKKYEEQQKQLSLYLDKIDNLENEKRQLEQEQNRIIMDSNKLLVRNEDYAIKVNQLEK 1400

Query: 1433 EFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKE 1479
             ++ ++QQL E + + E   Y ++ + +   L+++    H +T + +
Sbjct: 1401 TYQQLKQQLQEQQAQHEKQQYFQKEKNSNCNLRLNCQIFHCKTYKDQ 1447



 Score =  128 bits (310), Expect = 9e-28
 Identities = 254/1383 (18%), Positives = 592/1383 (42%), Gaps = 140/1383 (10%)

Query: 305  EEKTEIEEKGSLEI---ANMTELTKKIELLEHLNCQIRQT---NKELENKLATMGTESKA 358
            E KT+ ++   LE+     + +L ++I++ + L  QI+Q    N + +  +  +  ++  
Sbjct: 35   EVKTKNQQLSQLEMDYKGQVNQLQQQIQINQSLQLQIQQISQGNTDQKKAIEQLTDQNNQ 94

Query: 359  VSSPSKKGSPL--ISRKSGRNTASKMKSPWSQLSSETL----NQDTDKKINKNEIAKLEM 412
            + +  K+      I +   +    +  +   +L +E L    N D+ ++    +I++L+ 
Sbjct: 95   LKNQLKQVQETNNIEKDQSKQNLERANTDIQKLKNEILQLQRNNDSLQQQKTYQISQLDT 154

Query: 413  ----VIQSLNKDLVDKEYVISEK-DTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIH 467
                VI+ L + +   +   + K ++            D L+ ++ ++  +  +  +   
Sbjct: 155  NSKKVIEELQEQIRKMQLSATSKIESLTSELSLKNDQLDKLMKEINIKKNELYQSTANYE 214

Query: 468  V--GTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKN 525
                T ++ + +  ++Q++ +Q+ ND++    ++        A+ +ITQ+  EI    KN
Sbjct: 215  AVNATKSQQLIQAQQIQQKCQQDFNDKLAQFQLQ--------AQMKITQMEQEI--GQKN 264

Query: 526  MIKVKSNHKL--KLKQMQKTIDNFSKVSDSN-KEIVRLTEELHHLSQKV----AELEEEK 578
             I  K+N  L  K +++++   NF ++++ N K++ ++  ++  L   +     + + +K
Sbjct: 265  TIIEKANQDLAKKAQEIKENNQNFEQINNQNQKKLQQMMIQVQKLQLAIESENTQYDRKK 324

Query: 579  GNLQLHLVDYDSGRMIE---SDVYKKMI--EMENLAETRL----------KAISLLESQK 623
            G+L++ + + +    ++   S+ Y + +  E+  L    L          K++ L +++ 
Sbjct: 325  GDLKVQIDNLEKDLNMQQQSSNQYTQKLNNEINQLKNQNLDLQRQLSEKHKSLCLSQTES 384

Query: 624  FDLVQELHILQQKYD-EVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVI 682
               +++L++    +  E++ K   + Q +S  +  ++  V   +Q+  L   ++E  L+I
Sbjct: 385  DAQIKQLNLQVASFQKEIQLKNQQLQQAESQLLEMKVLKVQEIDQM-KLKFDQREKELLI 443

Query: 683  ENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHE 742
            +N +L+      + K +    E++  +++   Q   +  + L K + E I +L  +   +
Sbjct: 444  QNDQLNNNNKMQSQKVITLSNEELNRQIKQVDQFWTEKYNNLSKQTKEDIYQLTQQYQMQ 503

Query: 743  EQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQL 802
                 QT       I++      N + EL  +  ++  L + I  ++  R +   + D +
Sbjct: 504  LAQMDQTNKEKIYVIEQNHNQFLNSQKEL--FNVQLSLLNKQILDLQKERENSIIQLDLM 561

Query: 803  G---SYLQEKQKAYSEYTIQEDELV-NRLAVLMDHD----RVVEKQLLEIEHENKELQKK 854
                + LQ+K + ++    ++DEL+ N++A L +       V+ +Q L  + E   LQ K
Sbjct: 562  KVKLNELQDKTQNFNSRDQRKDELMQNQMATLKNSKEELLNVINQQNLAHKKEIYNLQTK 621

Query: 855  NQILLEENQN-----------LQISLSDMQQHYNALVEKANRTDL-----AESESTKYQT 898
               L ++  N           L++S  + QQ YN L  + N+  L      +SE  K Q+
Sbjct: 622  IDQLQQQYDNSVREGKQIKEQLKLSQLEAQQVYN-LSHQKNKESLNAQADKDSEIIKLQS 680

Query: 899  QLRDLESNLKRITHEHQTLIVQKK--KEIEDLEI-EFNTQIESAIRDKKVLNEKYEKNIE 955
            +L  +E+  K++  E + +  QK   + I+D ++ E + +I +       L +K ++  +
Sbjct: 681  ELSRVETLYKQVVLELKIINEQKNDLQVIDDFQLKEKDIEIGNQKSYILELKQKLQQLQK 740

Query: 956  YVTQLEAQLQEYKNNI----ENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEI 1011
             + +LE QLQ     +    +     +E LN+  + +  + +Q+++ +  +  E    E+
Sbjct: 741  RINELELQLQNANKKLGQKDQEAKKEIENLNQ-RITIQKRQIQEERERCDELAEAQEMEV 799

Query: 1012 NKLNALLKQK---DEEIIALNQKINNAQVSYMSMVSDYESKLAQF---TTKLENMEEEMQ 1065
               N  LK++   +E++I    ++         ++++ ++   QF   T + + ++E+ +
Sbjct: 800  QTWNERLKEQQKLNEDLIIQLMRLQQQTSQNSGLINELQNLKQQFEIVTNQYKQLQEDAE 859

Query: 1066 RVSKQLLDSKQHNEELQILVREQDDQIKEL-KETKLTFEMNI-PKTEGMIISSTIEPMSD 1123
              +KQ   S   N ++Q+L    + Q+  L ++ +   + N+  K E  I+   ++ ++ 
Sbjct: 860  EATKQ--KSMVKNVQIQMLQNHYNKQMDVLTQQLEDMKQSNLNQKLEFPIMDFNVQIIA- 916

Query: 1124 DANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQ---SAKLNTELQECYTKIIQLET 1180
                ++            LK Q +++ +++ SV+ +Q   + +L +E ++   +++    
Sbjct: 917  ----LNDLLVKKNAEINQLKSQTQQKLLEKDSVIDQQREYAQQLLSEFEKLQVQLMDQHE 972

Query: 1181 LNTELTGHDVVNQEQINQ---LKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAE 1237
                     ++N+E+ N    LK ++ +L  EN  L+    +L+   S  V Q   ++ +
Sbjct: 973  FQERADNLQMINEEKDNSIIYLKEEIAKLKQEN-KLIKGKLDLKEQ-SMVVIQDQQQLIK 1030

Query: 1238 LWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQN 1297
              K  L  ++ + Q  +  +  Q    +S   ++    +SS QE++      E    ++N
Sbjct: 1031 QLKIELQNKQKNIQPKQIAVSHQ-QTMKSSIHRMSKRSESSRQEKSEVDWNGESQFLMEN 1089

Query: 1298 KLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQ 1357
                     +   E + D    IE + SEI D  +                  DL    Q
Sbjct: 1090 GNNKLPCFHQQSSESFTD-NKLIEKMNSEIVDTNIRLRNQVDLLNQDKQSLQNDLTRTIQ 1148

Query: 1358 SYKQMQ-EQSILNINEENAQ-LKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSE 1415
            S  Q++ E S L +  +  Q   +SS            +    E  ++    Q+  K   
Sbjct: 1149 SLNQVKNENSELILKLQYVQKALESSQQNQEKLEREINQKKKKEINIVSFDDQINSKVKA 1208

Query: 1416 IYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLT---------------YEKESELA 1460
            + Q+      + TQ+      ++Q+  E  ++I+ L                  +  E  
Sbjct: 1209 MNQQLENLQSSKTQQTQLINQLQQEHSELYQQIDRLNDQNRELRKNITVINELNQTQEQQ 1268

Query: 1461 ILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTN 1520
            IL L+M        T+++ SE+   +L ++   +I      N+Q+ + N  L+ ++ + N
Sbjct: 1269 ILELQMKLKQEQLVTVKQNSEVRVFQLKQDQTSQIVSFE--NQQLKQQNVELQNKIQEQN 1326

Query: 1521 EMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKEL 1580
            ++ +  ENQ+ +   L  +    Q  +     KI        D  +    QL+   N+ +
Sbjct: 1327 QLISNYENQQQKKNGLEKKYEEQQKQLSLYLDKI--------DNLENEKRQLEQEQNRII 1378

Query: 1581 LDA 1583
            +D+
Sbjct: 1379 MDS 1381



 Score =  102 bits (245), Expect = 7e-20
 Identities = 180/932 (19%), Positives = 397/932 (42%), Gaps = 82/932 (8%)

Query: 678  LALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLA 737
            L   I++L+ + +     +  LE D +  +N+LQ  IQ N  L  +++++S     +  A
Sbjct: 25   LEFEIKSLQNEVKTKNQQLSQLEMDYKGQVNQLQQQIQINQSLQLQIQQISQGNTDQKKA 84

Query: 738  KINHEEQS-KIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLE 796
                 +Q+ +++ Q     ++QE +    NIE + SK    + R    I  +++    L+
Sbjct: 85   IEQLTDQNNQLKNQL---KQVQETN----NIEKDQSK--QNLERANTDIQKLKNEILQLQ 135

Query: 797  RKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLL---EIEHENKELQK 853
            R  D L    Q+K    S+      +++  L      +++ + QL    +IE    EL  
Sbjct: 136  RNNDSLQ---QQKTYQISQLDTNSKKVIEEL-----QEQIRKMQLSATSKIESLTSELSL 187

Query: 854  KNQILLEENQNLQISLSDMQQHYNALVEKANRT---DLAESESTKYQTQLRDLESNLKRI 910
            KN  L +  + + I  +++ Q   A  E  N T    L +++  + + Q +D    L + 
Sbjct: 188  KNDQLDKLMKEINIKKNELYQS-TANYEAVNATKSQQLIQAQQIQQKCQ-QDFNDKLAQF 245

Query: 911  THEHQTLIVQKKKEI--EDLEIE-FNTQIESAIRDKKVLNEKYEK----NIEYVTQLEAQ 963
              + Q  I Q ++EI  ++  IE  N  +    ++ K  N+ +E+    N + + Q+  Q
Sbjct: 246  QLQAQMKITQMEQEIGQKNTIIEKANQDLAKKAQEIKENNQNFEQINNQNQKKLQQMMIQ 305

Query: 964  LQEYKNNIENLNMNVEELN---KMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQ 1020
            +Q+ +  IE+ N   +      K+ ++ ++K +  QQ  S  YT++  NEIN+L      
Sbjct: 306  VQKLQLAIESENTQYDRKKGDLKVQIDNLEKDLNMQQQSSNQYTQKLNNEINQLKNQNLD 365

Query: 1021 KDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHN-E 1079
               ++   ++ +  +Q    + +     ++A F  +++   +++Q+   QLL+ K    +
Sbjct: 366  LQRQLSEKHKSLCLSQTESDAQIKQLNLQVASFQKEIQLKNQQLQQAESQLLEMKVLKVQ 425

Query: 1080 ELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXX 1139
            E+  +  + D + KEL         N       +I+ + E ++     VD          
Sbjct: 426  EIDQMKLKFDQREKELLIQNDQLNNNNKMQSQKVITLSNEELNRQIKQVD---QFWTEKY 482

Query: 1140 XXLKVQEEEEFIQERSVLQEQSAKLN-TELQECYTKIIQLETLNTELTGHDVVNQEQINQ 1198
              L  Q +E+  Q     Q Q A+++ T  ++ Y  +I+ +  N  L     +   Q++ 
Sbjct: 483  NNLSKQTKEDIYQLTQQYQMQLAQMDQTNKEKIY--VIE-QNHNQFLNSQKELFNVQLSL 539

Query: 1199 LKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELR 1258
            L  ++  L  E +N +  +  ++  ++   D+          Q+   R+   Q+ +  ++
Sbjct: 540  LNKQILDLQKERENSIIQLDLMKVKLNELQDK---------TQNFNSRD---QRKDELMQ 587

Query: 1259 VQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVIN 1318
             Q++  ++  E+LL+ +          +   +++ +LQ K+   ++   N   +   +  
Sbjct: 588  NQMATLKNSKEELLNVINQ------QNLAHKKEIYNLQTKIDQLQQQYDNSVREGKQIKE 641

Query: 1319 QIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXD-----LRTENQSYKQMQEQSILNINEE 1373
            Q+++  S++E ++V                  D     L++E    + + +Q +L +   
Sbjct: 642  QLKL--SQLEAQQVYNLSHQKNKESLNAQADKDSEIIKLQSELSRVETLYKQVVLELKII 699

Query: 1374 NAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDE 1433
            N Q                  + + ++ +LEL  +L+    ++ ++ +E  + L   N  
Sbjct: 700  NEQKNDLQVIDDFQLKEKDIEIGNQKSYILELKQKLQ----QLQKRINELELQLQNAN-- 753

Query: 1434 FENVRQQLVEYEKRIEDLTYE---KESELAILRLKMHENANHYETMQKESEIERVKLIEE 1490
             + + Q+  E +K IE+L      ++ ++   R +  E A   E M+ ++  ER+K  ++
Sbjct: 754  -KKLGQKDQEAKKEIENLNQRITIQKRQIQEERERCDELAEAQE-MEVQTWNERLKEQQK 811

Query: 1491 LNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVR-A 1549
            LN  +   +   +Q    N  L  E+    +    + NQ  ++    +E T  ++MV+  
Sbjct: 812  LNEDLIIQLMRLQQQTSQNSGLINELQNLKQQFEIVTNQYKQLQEDAEEATKQKSMVKNV 871

Query: 1550 SSSKIQKHVSFASDT-KQGRDEQLDNTMNKEL 1580
                +Q H +   D   Q  ++   + +N++L
Sbjct: 872  QIQMLQNHYNKQMDVLTQQLEDMKQSNLNQKL 903



 Score = 72.9 bits (171), Expect = 7e-11
 Identities = 111/580 (19%), Positives = 254/580 (43%), Gaps = 57/580 (9%)

Query: 1008 INEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRV 1067
            +N+ N+L   +K    E+   NQ+++  ++ Y   V+  + ++ Q     ++++ ++Q++
Sbjct: 19   LNKNNRLEFEIKSLQNEVKTKNQQLSQLEMDYKGQVNQLQQQI-QIN---QSLQLQIQQI 74

Query: 1068 SKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANN 1127
            S+   D K+  E+L     +  +Q+K+++ET      NI K +       +E  + D   
Sbjct: 75   SQGNTDQKKAIEQLTDQNNQLKNQLKQVQETN-----NIEKDQS---KQNLERANTDIQK 126

Query: 1128 VDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTE-LT 1186
            +             L+ Q+  +  Q    L   S K+  ELQE   K+    T   E LT
Sbjct: 127  LKNEILQLQRNNDSLQQQKTYQISQ----LDTNSKKVIEELQEQIRKMQLSATSKIESLT 182

Query: 1187 GHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQR 1246
                +  +Q+++L   ++++N + + L  + A    ++++   Q+  +  ++  Q   Q+
Sbjct: 183  SELSLKNDQLDKL---MKEINIKKNELYQSTANY-EAVNATKSQQLIQAQQI--QQKCQQ 236

Query: 1247 EADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHL 1306
            + + +  + +L+ Q+    ++ EQ +   +++  E+ N+ +  ++   ++   Q+ E+  
Sbjct: 237  DFNDKLAQFQLQAQMKI--TQMEQEIGQ-KNTIIEKANQDLA-KKAQEIKENNQNFEQIN 292

Query: 1307 RNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQS 1366
               Q+K   ++ Q++ L+  IE E   +                DL  + QS  Q  ++ 
Sbjct: 293  NQNQKKLQQMMIQVQKLQLAIESENTQYDRKKGDLKVQIDNLEKDLNMQQQSSNQYTQK- 351

Query: 1367 ILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTIT 1426
               +N E  QLK  +               D + ++ E    L L  +E   +  +  + 
Sbjct: 352  ---LNNEINQLKNQNL--------------DLQRQLSEKHKSLCLSQTESDAQIKQLNLQ 394

Query: 1427 LTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVK 1486
            +     E +   QQL + E ++ ++   K  E+  ++LK  +     E + +  ++    
Sbjct: 395  VASFQKEIQLKNQQLQQAESQLLEMKVLKVQEIDQMKLKFDQREK--ELLIQNDQLNNNN 452

Query: 1487 LIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNM 1546
             ++   V    +  LN+Q+ ++++   E+    ++ QT    ++I  +T   ++  L  M
Sbjct: 453  KMQSQKVITLSNEELNRQIKQVDQFWTEKYNNLSK-QT---KEDIYQLTQQYQM-QLAQM 507

Query: 1547 VRASSSKI----QKHVSFASDTKQGRDEQLDNTMNKELLD 1582
             + +  KI    Q H  F +  K+  + QL + +NK++LD
Sbjct: 508  DQTNKEKIYVIEQNHNQFLNSQKELFNVQL-SLLNKQILD 546


>UniRef50_Q23DA0 Cluster: Putative uncharacterized protein; n=1;
            Tetrahymena thermophila SB210|Rep: Putative
            uncharacterized protein - Tetrahymena thermophila SB210
          Length = 1404

 Score =  139 bits (337), Expect = 5e-31
 Identities = 237/1121 (21%), Positives = 491/1121 (43%), Gaps = 129/1121 (11%)

Query: 473  EDVNEIAKVQEQLKQELNDEIKDVNVK----DLIEKLKS-------AEEQITQLNDEIDA 521
            E +N + ++ E   Q L D I+DV  K    DLI+ +K          +++ +L +EI  
Sbjct: 61   ERINSMRELYEMRFQTLQDTIRDVYEKIIKDDLIQTMKDNPISQEYIHQRVRELFEEIVL 120

Query: 522  ANKNMIKVKSNHKLKLKQMQKTIDNFSKV-SDSNKEIVRLTEELHHLSQKVAELEE---- 576
            + + +I  K + +    + +     FSK+ ++  KE+ +  EE+   ++ +  L+E    
Sbjct: 121  SEREVIIDKLSSQYTFLKAE-----FSKLENEKRKELQQHDEEMEESARIINMLKEDLHK 175

Query: 577  EKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQK 636
            E+ N Q +  ++   +   ++V ++  +   L +   K    LE ++  ++Q    L QK
Sbjct: 176  ERQNRQFYEQEFQRMQKKMNEVTEQFEDA--LIKKEQKMQDKLEQEQNQVIQ----LTQK 229

Query: 637  YDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLD--KEQLYG 694
            ++++E +   + + Q+ Q+ SE + +    ++     S+K+L L    + L+  ++++  
Sbjct: 230  FNDLEKEYEQLIKSQN-QIFSENQELKQRGELMKADLSEKQLELNTYKIDLNTAEDKIKQ 288

Query: 695  TIKDLENDKEDIMNKLQNY---IQENMDLTDKLE--KMSAEKI-SELLAKINHEEQSKIQ 748
             +K  +N K ++      Y   ++EN  L  +LE  K+ A  I +++  K  H +Q+  +
Sbjct: 289  QLKLNDNLKLEVSQLSSRYNQLMEENTHLNMELENTKLDATTIENQMQQKFQHAQQNLQK 348

Query: 749  TQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQE 808
             Q  ++   Q+    +E  ++++ +YK R    E+ I  +         K DQ     +E
Sbjct: 349  GQEYLEKVKQKNKQKLEAYKNKIIEYKQRNQEAEQIIRQL---------KQDQN----EE 395

Query: 809  KQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQIS 868
            K+K+                 L + +R++++  +E E + +E+   +Q+  +ENQ     
Sbjct: 396  KEKSQKS--------------LQNWERILQETKIEYERKIEEIHNVSQMKFDENQRRHDE 441

Query: 869  -LSDMQQHY----NALVEKANRTDLAESESTKYQT-QLRD-LESNLKRITHE------HQ 915
             L ++Q HY    N  ++        E +  +YQ  QL+  LE  L ++  +      H 
Sbjct: 442  YLQELQLHYQETMNQKIDDIKNESNLEIDQLRYQERQLKQMLEEKLNQLQKDYISKSLHD 501

Query: 916  TLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYE--KNIEYVTQLEA----------- 962
             ++ +KKK I+ ++ +F+  +    ++ ++ NE+ E  KN E+  QL             
Sbjct: 502  EIMDEKKKSIDKMKQDFDHFLSEFKKETEMKNEQIELRKNKEHEQQLAYLQSNFFFDYFY 561

Query: 963  -QLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQK 1021
             Q + +K+  +NL    E L +  L+   + +Q +  Q  D  ++ I ++       +  
Sbjct: 562  NQFKSFKSKSDNLKELEESLREYKLQ--GRELQSKNEQLEDQQQKIIADLENQIKQNRIY 619

Query: 1022 DEEIIALNQKIN---NAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHN 1078
            + EI  L +K+N   N        + D +   AQ  + LE+    +QR S+ L +    N
Sbjct: 620  ESEIQRLQEKLNKQKNKNNELQKTLDDLDQLSAQLKSDLESSRSTIQRYSQDLENITVQN 679

Query: 1079 EELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXX 1138
            E+L   + EQ     + K  +L   ++  KTE       I+   +   N+          
Sbjct: 680  EKLFAQINEQ-----KQKNAELIGSVSNLKTEVSNGQQVIQFKEEVIKNIKENLEELKQE 734

Query: 1139 XXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQ 1198
               L  +  + + +E++   E  +K     +E  T+I +L+    E      + + Q++ 
Sbjct: 735  NKQLNTKFFDLY-KEKAQKNEDESK---RFEEINTQITRLQYEAQEKAHQSEILKSQLDT 790

Query: 1199 LKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELR 1258
            +  + + L  E   L   + E +  IS A  +   E+  L+ + L Q++    + ++EL 
Sbjct: 791  ISEQKKILEEEIQYLKIDLLE-KERISQASLREKLELENLFSKKLQQQKELKYQIKNELT 849

Query: 1259 VQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRN-LQEKYADVI 1317
            ++L+       Q+ + VQ   + ++N+I     V S+Q K +D      N LQEK   V 
Sbjct: 850  IELTRLRKDLSQIQEFVQHQIKMKSNEIELW--VKSIQGKSKDILNKQNNQLQEKLQIVE 907

Query: 1318 NQI-EILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQ 1376
            N+I      +I+D K  F                DL+ + +   +     +  +++ N  
Sbjct: 908  NEISRECEEQIQDYKHRF-----------EQEISDLQQQKEREIKQLSDYVNKLSQANQD 956

Query: 1377 LKKSSXXXXXXXXXXXXRVN--DAEAKVLELTHQLELKDSEIYQKTHEYTIT-LTQRNDE 1433
            L   S            + +    + + L+ ++   +K SE  ++T +  ++   QR +E
Sbjct: 957  LINESKGYQEELNELKNQYDLLQQQNQNLQKSYDNAIKKSEQMEQTFDLRLSEYQQRKEE 1016

Query: 1434 FENVRQQLVEYEKRI--EDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEEL 1491
                R+Q+VE E  I  E++   K     ++  +M++N    ++ Q+E E+E V+     
Sbjct: 1017 SGLKRKQMVERELDIANEEIIQWKNKYQNLID-QMNKNVEQMQS-QREIEVETVRQKMNF 1074

Query: 1492 NVKITES--VSLNKQVAELNKALEEEVAKTNEMQTALENQE 1530
            +++  ES    L +   EL  +L ++  K N +Q  ++ +E
Sbjct: 1075 SIQQLESQIEMLQQNELELRDSLAKQNDKINLLQKIIQEKE 1115



 Score =  116 bits (278), Expect = 7e-24
 Identities = 214/1114 (19%), Positives = 482/1114 (43%), Gaps = 99/1114 (8%)

Query: 473  EDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSN 532
            E++ E A++   LK++L+ E ++    +  ++ +  ++++ ++ ++ + A   +IK +  
Sbjct: 157  EEMEESARIINMLKEDLHKERQNRQFYE--QEFQRMQKKMNEVTEQFEDA---LIKKEQK 211

Query: 533  HKLKLKQMQKTIDNFS-KVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSG 591
             + KL+Q Q  +   + K +D  KE  +L +  + +  +  EL++    ++  L    S 
Sbjct: 212  MQDKLEQEQNQVIQLTQKFNDLEKEYEQLIKSQNQIFSENQELKQRGELMKADL----SE 267

Query: 592  RMIESDVYKKMIEMENLAETRLKA-ISLLESQKFDLVQELHILQQKYDEVEDKLADIS-Q 649
            + +E + YK  I++ N AE ++K  + L ++ K ++ Q    L  +Y+++ ++   ++ +
Sbjct: 268  KQLELNTYK--IDL-NTAEDKIKQQLKLNDNLKLEVSQ----LSSRYNQLMEENTHLNME 320

Query: 650  LQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNK 709
            L++ ++ +      ++++      + ++    +E +K   +Q     K+   + +    +
Sbjct: 321  LENTKLDATTIENQMQQKFQHAQQNLQKGQEYLEKVKQKNKQKLEAYKNKIIEYKQRNQE 380

Query: 710  LQNYIQE-NMDLTDKLEKM--SAEKISELLAKINHEEQSKIQ-----TQFGIDAKIQERD 761
             +  I++   D  ++ EK   S +    +L +   E + KI+     +Q   D   +  D
Sbjct: 381  AEQIIRQLKQDQNEEKEKSQKSLQNWERILQETKIEYERKIEEIHNVSQMKFDENQRRHD 440

Query: 762  LYIENIESELSK-YKSRICRLE-ESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQ 819
             Y++ ++    +    +I  ++ ES   ++  RY   +    L   L + QK Y   ++ 
Sbjct: 441  EYLQELQLHYQETMNQKIDDIKNESNLEIDQLRYQERQLKQMLEEKLNQLQKDYISKSLH 500

Query: 820  EDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQH---- 875
             DE+++     +D  +      L  E + +   K  QI L +N+  +  L+ +Q +    
Sbjct: 501  -DEIMDEKKKSIDKMKQDFDHFLS-EFKKETEMKNEQIELRKNKEHEQQLAYLQSNFFFD 558

Query: 876  --YNALVEKANRTD-LAESEST--KYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEI 930
              YN      +++D L E E +  +Y+ Q R+L+S  +++  + Q +I   + +I+   I
Sbjct: 559  YFYNQFKSFKSKSDNLKELEESLREYKLQGRELQSKNEQLEDQQQKIIADLENQIKQNRI 618

Query: 931  -EFNTQ-IESAIRDKKVLNEKYEKNIEYVTQLEAQL-----------QEYKNNIENLNMN 977
             E   Q ++  +  +K  N + +K ++ + QL AQL           Q Y  ++EN+ + 
Sbjct: 619  YESEIQRLQEKLNKQKNKNNELQKTLDDLDQLSAQLKSDLESSRSTIQRYSQDLENITVQ 678

Query: 978  VEELNKMNLELIDKHVQKQQTQSPDYTEQYINE--INKLNALLKQKDEEIIALNQKINNA 1035
             E+L     E   K+ +   + S   TE    +  I     ++K   E +  L Q+    
Sbjct: 679  NEKLFAQINEQKQKNAELIGSVSNLKTEVSNGQQVIQFKEEVIKNIKENLEELKQENKQL 738

Query: 1036 QVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKEL 1095
               +  +  +   K    + + E +  ++ R+  +  +    +E L+  +    +Q K L
Sbjct: 739  NTKFFDLYKEKAQKNEDESKRFEEINTQITRLQYEAQEKAHQSEILKSQLDTISEQKKIL 798

Query: 1096 KETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERS 1155
            +E     ++++ + E +  +S  E +      ++            LK Q + E   E +
Sbjct: 799  EEEIQYLKIDLLEKERISQASLREKLE-----LENLFSKKLQQQKELKYQIKNELTIELT 853

Query: 1156 VLQEQSAKLNTELQ---ECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTE--- 1209
             L++  +++   +Q   +  +  I+L   + +    D++N++  NQL+ KL+ +  E   
Sbjct: 854  RLRKDLSQIQEFVQHQIKMKSNEIELWVKSIQGKSKDILNKQN-NQLQEKLQIVENEISR 912

Query: 1210 --NDNLLSTVAELRSSISSAVDQRGFEIAEL--WKQHLAQREADFQKTEHELRVQLSAFE 1265
               + +          IS    Q+  EI +L  +   L+Q   D        + +L+  +
Sbjct: 913  ECEEQIQDYKHRFEQEISDLQQQKEREIKQLSDYVNKLSQANQDLINESKGYQEELNELK 972

Query: 1266 SKYEQLLD---SVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEI 1322
            ++Y+ L     ++Q S      K   MEQ   L+     + +    L+ K   V  +++I
Sbjct: 973  NQYDLLQQQNQNLQKSYDNAIKKSEQMEQTFDLRLSEYQQRKEESGLKRKQM-VERELDI 1031

Query: 1323 LRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSX 1382
               EI   K  +                 +   N++ +QMQ Q  + +  E  + K +  
Sbjct: 1032 ANEEIIQWKNKYQNL--------------IDQMNKNVEQMQSQREIEV--ETVRQKMNFS 1075

Query: 1383 XXXXXXXXXXXRVNDAEAK--VLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQ 1440
                       + N+ E +  + +   ++ L    I +K   +     +++ + ++V + 
Sbjct: 1076 IQQLESQIEMLQQNELELRDSLAKQNDKINLLQKIIQEKEEAFEGLRREKDQQIKSVTEV 1135

Query: 1441 LVEYEKRIEDLTYEKESELAILRLKMHENANHY--ETMQKESEIERVKLIEELNVKITES 1498
             +EY+ + E L  +K+S   ILR +  E  NH+  E     S+I   +LIEE  + I ++
Sbjct: 1136 ELEYKLKEEGLRKQKKSYDEILR-EQEEKINHFVNEITILNSKIN--QLIEEKTILINKN 1192

Query: 1499 VSLNKQVAELNKALEEEVAKTNEMQTALENQEIE 1532
              L  Q+ +L ++   ++AK    +    N+EIE
Sbjct: 1193 KDLQFQL-DLKQSQLNQLAKEFHDKQTKSNKEIE 1225



 Score =  108 bits (259), Expect = 1e-21
 Identities = 186/1034 (17%), Positives = 431/1034 (41%), Gaps = 62/1034 (5%)

Query: 212  EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLE-EANKLLEAARFEISLE 270
            E   +Q+ K Q    +   E K   + +  D+  K + +++ + + N   +  + ++ L 
Sbjct: 234  EKEYEQLIKSQNQIFSENQELKQRGELMKADLSEKQLELNTYKIDLNTAEDKIKQQLKL- 292

Query: 271  HSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTE-LTKKIE 329
            +  L  E+ Q              L    +E +  + T IE +   +  +  + L K  E
Sbjct: 293  NDNLKLEVSQLSSRYNQLMEENTHL-NMELENTKLDATTIENQMQQKFQHAQQNLQKGQE 351

Query: 330  LLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQL 389
             LE +  + +Q  +  +NK+      ++      ++      +   +  + K    W ++
Sbjct: 352  YLEKVKQKNKQKLEAYKNKIIEYKQRNQEAEQIIRQLKQ--DQNEEKEKSQKSLQNWERI 409

Query: 390  SSETLNQDTDKKINK-NEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTL 448
              ET   + ++KI + + +++++        D   +E  +  ++T            +  
Sbjct: 410  LQET-KIEYERKIEEIHNVSQMKFDENQRRHDEYLQELQLHYQETMNQKIDDIKNESNLE 468

Query: 449  IAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSA 508
            I QL+ + +Q  +           E +N++ K  + + + L+DEI D   K + +  +  
Sbjct: 469  IDQLRYQERQLKQ--------MLEEKLNQLQK--DYISKSLHDEIMDEKKKSIDKMKQDF 518

Query: 509  EEQITQLNDEIDAANKNM-IKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHL 567
            +  +++   E +  N+ + ++    H+ +L  +Q     F    +  K     ++ L  L
Sbjct: 519  DHFLSEFKKETEMKNEQIELRKNKEHEQQLAYLQSNFF-FDYFYNQFKSFKSKSDNLKEL 577

Query: 568  SQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLV 627
             + + E + +   LQ           +E    K + ++EN    ++K   + ES+   L 
Sbjct: 578  EESLREYKLQGRELQ------SKNEQLEDQQQKIIADLEN----QIKQNRIYESEIQRLQ 627

Query: 628  QELHILQQKYDEVEDKLADI----SQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIE 683
            ++L+  + K +E++  L D+    +QL+SD   S        + ++ ++   ++L   I 
Sbjct: 628  EKLNKQKNKNNELQKTLDDLDQLSAQLKSDLESSRSTIQRYSQDLENITVQNEKLFAQIN 687

Query: 684  NLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEE 743
              K    +L G++ +L+ +  +    +Q   +   ++ + LE++  E   +L  K     
Sbjct: 688  EQKQKNAELIGSVSNLKTEVSNGQQVIQFKEEVIKNIKENLEELKQEN-KQLNTKFFDLY 746

Query: 744  QSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLG 803
            + K Q       + +E +  I  ++ E  +   +   L+  +  + +++  LE +   L 
Sbjct: 747  KEKAQKNEDESKRFEEINTQITRLQYEAQEKAHQSEILKSQLDTISEQKKILEEEIQYLK 806

Query: 804  SYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLL-EIEHENKELQKK-NQILLEE 861
              L EK++       ++ EL N  +  +   + ++ Q+  E+  E   L+K  +QI    
Sbjct: 807  IDLLEKERISQASLREKLELENLFSKKLQQQKELKYQIKNELTIELTRLRKDLSQIQEFV 866

Query: 862  NQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEH-QTLIVQ 920
               +++  ++++    ++  K+   D+   ++ + Q +L+ +E+ + R   E  Q    +
Sbjct: 867  QHQIKMKSNEIELWVKSIQGKSK--DILNKQNNQLQEKLQIVENEISRECEEQIQDYKHR 924

Query: 921  KKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEE 980
             ++EI DL+ +   +I+        L++  +  I      + +L E KN  + L    + 
Sbjct: 925  FEQEISDLQQQKEREIKQLSDYVNKLSQANQDLINESKGYQEELNELKNQYDLLQQQNQN 984

Query: 981  LNKMNLELIDKHVQKQQT---QSPDYTEQYINEINKLNALLKQK----DEEIIALNQKIN 1033
            L K     I K  Q +QT   +  +Y ++      K   +++++    +EEII    K  
Sbjct: 985  LQKSYDNAIKKSEQMEQTFDLRLSEYQQRKEESGLKRKQMVERELDIANEEIIQWKNKYQ 1044

Query: 1034 NAQVSYMSMVSDYESKLA-QFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQI 1092
            N        V   +S+   +  T  + M   +Q++  Q+   +Q+  EL+  + +Q+D+I
Sbjct: 1045 NLIDQMNKNVEQMQSQREIEVETVRQKMNFSIQQLESQIEMLQQNELELRDSLAKQNDKI 1104

Query: 1093 ----KELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEE 1148
                K ++E +  FE  + + +   I S  E   +     +            L+ QEE+
Sbjct: 1105 NLLQKIIQEKEEAFE-GLRREKDQQIKSVTEVELEYKLKEEGLRKQKKSYDEILREQEEK 1163

Query: 1149 --EFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQL 1206
               F+ E ++L   ++K+N  ++E    I + + L  +L     + Q Q+NQL  +    
Sbjct: 1164 INHFVNEITIL---NSKINQLIEEKTILINKNKDLQFQLD----LKQSQLNQLAKEFHDK 1216

Query: 1207 NTENDNLLSTVAEL 1220
             T+++  +  + +L
Sbjct: 1217 QTKSNKEIEDLHKL 1230



 Score =   99 bits (238), Expect = 5e-19
 Identities = 173/969 (17%), Positives = 407/969 (42%), Gaps = 88/969 (9%)

Query: 651  QSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYG---TIKDLENDKEDIM 707
            Q  QV S  +S  +   +  ++++ ++ A  I      +EQL      I+D+E D  + +
Sbjct: 4    QEFQVSSPQQSETMNTGLSNINSADQQHAFRINQYFQGQEQLLDQQINIQDVEMDYNERI 63

Query: 708  NKLQNYIQENMD-----LTDKLEKMSAEKISELLAK--INHEEQSKIQTQFGIDAKIQER 760
            N ++   +         + D  EK+  + + + +    I+ E   +   +   +  + ER
Sbjct: 64   NSMRELYEMRFQTLQDTIRDVYEKIIKDDLIQTMKDNPISQEYIHQRVRELFEEIVLSER 123

Query: 761  DLYIENIESELSKYKSRICRLE-ESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQ 819
            ++ I+ + S+ +  K+   +LE E    ++     +E  A  +    ++  K        
Sbjct: 124  EVIIDKLSSQYTFLKAEFSKLENEKRKELQQHDEEMEESARIINMLKEDLHKERQNRQFY 183

Query: 820  EDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQIS--LSDMQQHYN 877
            E E       + +     E  L++     KE + ++++  E+NQ +Q++   +D+++ Y 
Sbjct: 184  EQEFQRMQKKMNEVTEQFEDALIK-----KEQKMQDKLEQEQNQVIQLTQKFNDLEKEYE 238

Query: 878  ALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIE 937
             L++  N+   +E++  K + +L  ++++L            +K+ E+   +I+ NT  E
Sbjct: 239  QLIKSQNQI-FSENQELKQRGEL--MKADLS-----------EKQLELNTYKIDLNTA-E 283

Query: 938  SAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQ 997
              I+ +  LN+  +  +  ++    QL E     EN ++N+E     N +L    ++ Q 
Sbjct: 284  DKIKQQLKLNDNLKLEVSQLSSRYNQLME-----ENTHLNME---LENTKLDATTIENQM 335

Query: 998  TQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKL 1057
             Q   + +Q + +  +    +KQK+++ +   +   N  + Y     + E  + Q     
Sbjct: 336  QQKFQHAQQNLQKGQEYLEKVKQKNKQKL---EAYKNKIIEYKQRNQEAEQIIRQLK--- 389

Query: 1058 ENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISST 1117
            ++  EE ++  K L + ++  +E +I    + ++I  + + K  F+ N  + +  +    
Sbjct: 390  QDQNEEKEKSQKSLQNWERILQETKIEYERKIEEIHNVSQMK--FDENQRRHDEYLQELQ 447

Query: 1118 IEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQ 1177
            +         +D            L+ QE     Q + +L+E   KLN   ++  +K + 
Sbjct: 448  LHYQETMNQKIDDIKNESNLEIDQLRYQER----QLKQMLEE---KLNQLQKDYISKSLH 500

Query: 1178 LETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNL-LSTVAELRSSISSAVDQRGFEIA 1236
             E ++ +    D + Q+  + L    ++   +N+ + L    E    ++       F+  
Sbjct: 501  DEIMDEKKKSIDKMKQDFDHFLSEFKKETEMKNEQIELRKNKEHEQQLAYLQSNFFFDYF 560

Query: 1237 ELWKQHLAQREADFQKTEHELR---VQLSAFESKYEQLLDSVQSSTQEETNKI----VTM 1289
                +    +  + ++ E  LR   +Q    +SK EQL D  Q    +  N+I    +  
Sbjct: 561  YNQFKSFKSKSDNLKELEESLREYKLQGRELQSKNEQLEDQQQKIIADLENQIKQNRIYE 620

Query: 1290 EQVTSLQNKLQDKEEHLRNLQEKYADVINQIEI-LRSEIEDEKVAFXXXXXXXXXXXXXX 1348
             ++  LQ KL +K+++  N  +K  D ++Q+   L+S++E  +                 
Sbjct: 621  SEIQRLQEKL-NKQKNKNNELQKTLDDLDQLSAQLKSDLESSR--------STIQRYSQD 671

Query: 1349 XXDLRTENQS-YKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTH 1407
              ++  +N+  + Q+ EQ      ++NA+L  S              +   E  +  +  
Sbjct: 672  LENITVQNEKLFAQINEQK-----QKNAELIGSVSNLKTEVSNGQQVIQFKEEVIKNIKE 726

Query: 1408 QLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYE---KESELAILRL 1464
             LE    E  Q   ++     ++  + E+  ++  E   +I  L YE   K  +  IL+ 
Sbjct: 727  NLEELKQENKQLNTKFFDLYKEKAQKNEDESKRFEEINTQITRLQYEAQEKAHQSEILKS 786

Query: 1465 KMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQT 1524
            ++   +   + +++E +  ++ L+E+  +      SL +++ EL     +++ +  E++ 
Sbjct: 787  QLDTISEQKKILEEEIQYLKIDLLEKERIS---QASLREKL-ELENLFSKKLQQQKELKY 842

Query: 1525 ALENQ-EIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDA 1583
             ++N+  IE+  L  +++ +Q  V+         +     + QG+ + + N  N +L + 
Sbjct: 843  QIKNELTIELTRLRKDLSQIQEFVQHQIKMKSNEIELWVKSIQGKSKDILNKQNNQLQEK 902

Query: 1584 VPRAELDLA 1592
            +   E +++
Sbjct: 903  LQIVENEIS 911



 Score = 97.5 bits (232), Expect = 3e-18
 Identities = 169/816 (20%), Positives = 345/816 (42%), Gaps = 77/816 (9%)

Query: 331  LEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLS 390
            ++ L  Q RQ  + LE KL  +    K   S S     +  +K    +  KMK  +    
Sbjct: 469  IDQLRYQERQLKQMLEEKLNQL---QKDYISKSLHDEIMDEKKK---SIDKMKQDFDHFL 522

Query: 391  SETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIA 450
            SE   ++T+ K  + E+ K +   Q L    +   +     D             D L  
Sbjct: 523  SE-FKKETEMKNEQIELRKNKEHEQQLA--YLQSNFFF---DYFYNQFKSFKSKSDNLKE 576

Query: 451  QLQLEHQQHMEGPSLIHVGTNTEDVNE--IAKVQEQLKQELNDEIKDVNVKDLIEKLKSA 508
              +   +  ++G  L       ED  +  IA ++ Q+KQ   + I +  ++ L EKL   
Sbjct: 577  LEESLREYKLQGRELQSKNEQLEDQQQKIIADLENQIKQ---NRIYESEIQRLQEKLNKQ 633

Query: 509  EEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLS 568
            + +  +L   +D  ++   ++KS+ +     +Q+   +   ++  N+   +L  +++   
Sbjct: 634  KNKNNELQKTLDDLDQLSAQLKSDLESSRSTIQRYSQDLENITVQNE---KLFAQINEQK 690

Query: 569  QKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQ 628
            QK AEL     NL+  + +       + +V K +   ENL E + +    L ++ FDL +
Sbjct: 691  QKNAELIGSVSNLKTEVSNGQQVIQFKEEVIKNI--KENLEELKQEN-KQLNTKFFDLYK 747

Query: 629  ELHILQQKYDE---VEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENL 685
            E    Q+  DE    E+    I++LQ +      +S  L+ Q+D +S  KK L   I+ L
Sbjct: 748  EK--AQKNEDESKRFEEINTQITRLQYEAQEKAHQSEILKSQLDTISEQKKILEEEIQYL 805

Query: 686  KLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQS 745
            K+D  +     +    +K ++ N     +Q+  +L  +++     +++ L   ++ + Q 
Sbjct: 806  KIDLLEKERISQASLREKLELENLFSKKLQQQKELKYQIKNELTIELTRLRKDLS-QIQE 864

Query: 746  KIQTQFGIDAKIQERDLYIENIESELSKYKSRIC-RLEESIAVME------------DRR 792
             +Q Q  I  K  E +L++++I+ +     ++   +L+E + ++E            D +
Sbjct: 865  FVQHQ--IKMKSNEIELWVKSIQGKSKDILNKQNNQLQEKLQIVENEISRECEEQIQDYK 922

Query: 793  YSLERKADQLGSYLQEKQKAYSEYTIQ----EDELVNRLAVLMDHDRVVEKQLLEIEHEN 848
            +  E++   L    + + K  S+Y  +      +L+N      +    ++ Q   ++ +N
Sbjct: 923  HRFEQEISDLQQQKEREIKQLSDYVNKLSQANQDLINESKGYQEELNELKNQYDLLQQQN 982

Query: 849  KELQKK--NQILLEEN--QNLQISLSDMQQHY--NALVEKA---NRTDLAESE----STK 895
            + LQK   N I   E   Q   + LS+ QQ    + L  K       D+A  E      K
Sbjct: 983  QNLQKSYDNAIKKSEQMEQTFDLRLSEYQQRKEESGLKRKQMVERELDIANEEIIQWKNK 1042

Query: 896  YQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIE 955
            YQ  +  +  N++++  + +  +   ++++     +  +QIE   +++  L +   K  +
Sbjct: 1043 YQNLIDQMNKNVEQMQSQREIEVETVRQKMNFSIQQLESQIEMLQQNELELRDSLAKQND 1102

Query: 956  YVTQLEAQLQEYKNNIENL----NMNVEELNKMNLE--LIDKHVQKQQ-------TQSPD 1002
             +  L+  +QE +   E L    +  ++ + ++ LE  L ++ ++KQ+        +  +
Sbjct: 1103 KINLLQKIIQEKEEAFEGLRREKDQQIKSVTEVELEYKLKEEGLRKQKKSYDEILREQEE 1162

Query: 1003 YTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEE 1062
                ++NEI  LN+ + Q  EE   L  K  + Q       S       +F  K     +
Sbjct: 1163 KINHFVNEITILNSKINQLIEEKTILINKNKDLQFQLDLKQSQLNQLAKEFHDKQTKSNK 1222

Query: 1063 EMQRVSKQLLDSKQH---NEELQILVREQDDQIKEL 1095
            E++ + K L  S ++   N E   L R+ D++ + L
Sbjct: 1223 EIEDLHKLLTQSFKNMNDNSENIDLARKLDEETRLL 1258



 Score = 51.2 bits (117), Expect = 2e-04
 Identities = 127/638 (19%), Positives = 264/638 (41%), Gaps = 67/638 (10%)

Query: 147  LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXX 206
            +SN   E  N   V+Q K    E  I +++E + E  Q  +  N                
Sbjct: 700  VSNLKTEVSNGQQVIQFK----EEVIKNIKENLEELKQENKQLNTKFFDLYKEKAQKNED 755

Query: 207  XXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFE 266
                 E+   Q+T++Q      EA+ K  +  +LK       ++ ++ E  K+LE     
Sbjct: 756  ESKRFEEINTQITRLQ-----YEAQEKAHQSEILKS------QLDTISEQKKILEE---- 800

Query: 267  ISLEHSKL-AQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELT 325
              +++ K+   E E+              L  + ++   E K +I+ + ++E+  + +  
Sbjct: 801  -EIQYLKIDLLEKERISQASLREKLELENLFSKKLQQQKELKYQIKNELTIELTRLRKDL 859

Query: 326  KKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSP 385
             +I+  E +  QI+  + E+E  +       K++   SK     I  K       K++  
Sbjct: 860  SQIQ--EFVQHQIKMKSNEIELWV-------KSIQGKSKD----ILNKQNNQLQEKLQIV 906

Query: 386  WSQLSSETLNQDTDKKIN-KNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXG 444
             +++S E   Q  D K   + EI+ L+   +   K L D    +S+ +            
Sbjct: 907  ENEISRECEEQIQDYKHRFEQEISDLQQQKEREIKQLSDYVNKLSQANQDLINESKGYQE 966

Query: 445  K-DTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIE 503
            + + L  Q  L  QQ+             +  +   K  EQ++Q  +  + +   +    
Sbjct: 967  ELNELKNQYDLLQQQNQ---------NLQKSYDNAIKKSEQMEQTFDLRLSEYQQR---- 1013

Query: 504  KLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVR--LT 561
            K +S  ++   +  E+D AN+ +I+ K+ ++  + QM K ++      +   E VR  + 
Sbjct: 1014 KEESGLKRKQMVERELDIANEEIIQWKNKYQNLIDQMNKNVEQMQSQREIEVETVRQKMN 1073

Query: 562  EELHHLSQKVAELEEEKGNLQLHLV-DYDSGRMIESDVYKKMIEMENL---AETRLKAIS 617
              +  L  ++  L++ +  L+  L    D   +++  + +K    E L    + ++K+++
Sbjct: 1074 FSIQQLESQIEMLQQNELELRDSLAKQNDKINLLQKIIQEKEEAFEGLRREKDQQIKSVT 1133

Query: 618  LLESQKFDLVQE-LHILQQKYDEV-EDKLADISQLQSDQVCSEIKSVHLEEQIDALSASK 675
             +E + + L +E L   ++ YDE+  ++   I+   ++      K   L E+   L    
Sbjct: 1134 EVELE-YKLKEEGLRKQKKSYDEILREQEEKINHFVNEITILNSKINQLIEEKTILINKN 1192

Query: 676  KELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISEL 735
            K+L      L L + QL    K+  +DK+   NK    + + +  + K    ++E I +L
Sbjct: 1193 KDLQF---QLDLKQSQLNQLAKEF-HDKQTKSNKEIEDLHKLLTQSFKNMNDNSENI-DL 1247

Query: 736  LAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSK 773
              K+  +E++++ T+   D  +Q  + Y+E  +S  SK
Sbjct: 1248 ARKL--DEETRLLTKKVKD--LQHINRYLEISKSPSSK 1281


>UniRef50_UPI0000F2D5B2 Cluster: PREDICTED: similar to centromere
            protein E; n=2; Mammalia|Rep: PREDICTED: similar to
            centromere protein E - Monodelphis domestica
          Length = 2638

 Score =  139 bits (336), Expect = 7e-31
 Identities = 235/1240 (18%), Positives = 536/1240 (43%), Gaps = 101/1240 (8%)

Query: 147  LSNTIKEKDNALSVLQVK---MKIMETTILDLQEKINEKDQI---IEAKNKATTXXXXXX 200
            L++T ++ +  +  LQ K   M  +   +++ QEK+NE +QI   +E+KN          
Sbjct: 1118 LADTEEKLNKKIQELQEKENQMLNVRKEVIEAQEKVNEMEQIRNQLESKNSTLERVEIEN 1177

Query: 201  XXXXXXXXXXXEDTK---QQMTKMQENFIAMEAEWKDEKQRLLKDIESK------DVRIS 251
                       E T    Q++ + ++  +A++ E +D+ +  +K++ +K      ++RI+
Sbjct: 1178 LKLAQKLQASLEQTSSITQEINEFKKTQVALQLE-RDQLKENIKEVVTKGLETQEELRIA 1236

Query: 252  --SLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXL--AKQSIEPSCEEK 307
               L++  + ++  +  +S + +++++  E               L   K+ +    EE 
Sbjct: 1237 QMGLKDHQETIDRLKECVSEKVAQVSKNQEAFEKTKAELQEKIQELQEKKEQVVNVREEN 1296

Query: 308  TEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGS 367
            +E+EEK    +  + +L K+++  E    +I   N EL  KL     E+  V+       
Sbjct: 1297 SEVEEK----VIEIEQLKKQLKTKECTLERIEMENLELAQKLQASLEETTCVAK------ 1346

Query: 368  PLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYV 427
                R               QL  ET+ +D   KI + E AK E +     +D  D+   
Sbjct: 1347 ---ERDELTKIQEAFYIEMEQL-KETI-RDLRAKIQELE-AKQEQIFNVREEDNEDQ--- 1397

Query: 428  ISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHME--GPSLIHVGTNTEDVNEIAKVQEQL 485
              EK             K++++ ++ LE+ +  +    SL    +  E+ +E+ K++E L
Sbjct: 1398 --EKMKEMEQLKEQLMSKESILERISLENLELAQKLQASLEETTSVAEERDELTKIKEAL 1455

Query: 486  ---KQELNDEIKDVNVKDL--IEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQM 540
               + +L + I+D+  KDL   E+L+ A+  + +  + +D   K  I  K + +    Q+
Sbjct: 1456 HIERDQLKETIRDLRAKDLEIQEELRIAQMSLKEHQETVDKL-KECISEKEDIEKTSAQL 1514

Query: 541  QKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYK 600
            Q+ I    ++  + +++  + EE++   + + E+E+ K  L       +   M   ++ +
Sbjct: 1515 QEKI---QELQTNQEQMFSVREEINKTQENIKEVEQLKEQLMSKESSLERIEMENLELAQ 1571

Query: 601  K----MIEMENLAETRLKAISLLES---QKFDLVQELHILQQKYDEVEDKLADISQLQSD 653
            K    + E+ ++A+ R +   + E+   ++  L + +  L+ K  E+E K   +  ++ +
Sbjct: 1572 KLQASLEEINSVAKERDELTKIQEAFYIERDQLKEAIRDLRAKIQELESKQEQMFNVREE 1631

Query: 654  QVCSEIKSVHLEEQIDALSASKKELALV-IENLKLDKEQLYGTIKDLEN--DKEDIMNKL 710
               ++ K   +E+  + L + +  L  + +ENL+L  ++L  ++++  +  ++ D + K+
Sbjct: 1632 DNEAQEKMKEMEQLKEQLISKESTLERISLENLEL-AQKLQASLEETTSVAEERDELTKI 1690

Query: 711  QNYIQ-ENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIES 769
            +  +  E   L + +  + A+ + E+  ++   ++S  + Q  +D K++E     E++E 
Sbjct: 1691 KEALHIERDQLKETIRDLRAKDL-EIQEELRIAQKSLKEHQETVD-KLKECISEKEDVEK 1748

Query: 770  ELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAV 829
              ++ + +    +E + + +      +   D+L   + EK+    +   Q  E +  L  
Sbjct: 1749 TSAQLQEKDLETQEELRIAQKSLKEHQETVDKLKECISEKEDV-EKTRAQLQEKIQELES 1807

Query: 830  LMDHDRVVEKQLLEIEHENKEL-QKKNQILLEENQNLQISLSDMQ--QHYNALVEKANRT 886
                   V ++  E + + KE+ Q K Q++ +E    +ISL +++  Q   A +E+    
Sbjct: 1808 KQKQMFNVREEDNEAQEKMKEMEQLKEQLISKEFTLERISLENLELAQKLQASLEETTSV 1867

Query: 887  DLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVL 946
                 E TK +  L      LK+   + +   ++ ++E+   ++      E+  R K+ +
Sbjct: 1868 AEERDELTKIKEALHIERDQLKKTIRDLRAKGLETQEELRIAQMGLKDHQETIDRLKECV 1927

Query: 947  NEK---YEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDY 1003
            +EK     KN E   + +A+LQE    ++     V  + + N E+ +K ++ +Q +    
Sbjct: 1928 SEKVAQVSKNQEAFEKTKAELQEKIQELQEKKEQVVNVREENSEVEEKVIEIEQLKKQLK 1987

Query: 1004 TEQ-YINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEE 1062
            T++  +  I   N  L QK +  +     +   +     +   +  ++ Q    + ++  
Sbjct: 1988 TKECTLERIEMENLELAQKLQASLEETTCVTKERDELTKIQEAFYIEMEQLKETIRDLRA 2047

Query: 1063 EMQRVSKQLL--------DSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMII 1114
            + Q+  K+L+        D KQH  E    ++E+  +I EL++     E          +
Sbjct: 2048 KNQQKPKELVKMEATARKDIKQHPIE---SLKEKCSKINELQKKYTMMENRCGFLSK--L 2102

Query: 1115 SSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTK 1174
            S  ++   +  N +             L    E+     R        + N +L    T 
Sbjct: 2103 SVDLKKAFESQNELQVKVRASLYHTPQLTKAVEKILASNR--------RCNNDLHSSSTC 2154

Query: 1175 II-QLETLNTELTGHDVVNQEQINQLKSKL-EQLNTENDNLLSTVAELRSSISSAVDQRG 1232
            I+ +LE +   + G    +   +N+ +  L  +   +N+ L+ T    + S   +++  G
Sbjct: 2155 ILRKLEGVLKRVVGLRKEHHTTVNKFQMDLIREAERQNELLVKTQHLQQHSQGGSLESSG 2214

Query: 1233 FEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQV 1292
            +++++    H+ Q   D  +T++++   ++ F    +QLL++ +         + T   V
Sbjct: 2215 YKLSQKMNLHVEQILKDVSETQNDVHNMIAEF----QQLLNAKKEIILFLDVCLNTHFDV 2270

Query: 1293 TSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKV 1332
              L+  +Q++ + + N+   Y + I  I    SE ED+ +
Sbjct: 2271 ECLKKVIQEENDRIVNVNNSYCNKIKAIINESSEFEDKSI 2310



 Score =  126 bits (303), Expect = 7e-27
 Identities = 251/1175 (21%), Positives = 517/1175 (44%), Gaps = 151/1175 (12%)

Query: 215  KQQMTKMQENFIAMEAEWKDEK-QRLLKDIESK-DVRISSLEEANKLLEAARFEISLEHS 272
            KQQ   ++E     E E +  + Q  L D E K + +I  L+E    +   R E+ +E  
Sbjct: 1092 KQQEAVLKERRKTAEKEGELVRTQERLADTEEKLNKKIQELQEKENQMLNVRKEV-IEAQ 1150

Query: 273  KLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLE 332
            +   E+EQ              +  ++++ + + +  +E+  S+    + E  K    L+
Sbjct: 1151 EKVNEMEQIRNQLESKNSTLERVEIENLKLAQKLQASLEQTSSIT-QEINEFKKTQVALQ 1209

Query: 333  HLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQ-LSS 391
                Q+++  KE+     T G E++     ++ G      K  + T  ++K   S+ ++ 
Sbjct: 1210 LERDQLKENIKEV----VTKGLETQEELRIAQMGL-----KDHQETIDRLKECVSEKVAQ 1260

Query: 392  ETLNQDTDKKINKNEIAKLEMVIQSLNKDLV---DKEYVISEKDTXXXXXXXXXXGKDTL 448
             + NQ+  +K  K E+ +    +Q   + +V   ++   + EK             K+  
Sbjct: 1261 VSKNQEAFEK-TKAELQEKIQELQEKKEQVVNVREENSEVEEKVIEIEQLKKQLKTKECT 1319

Query: 449  IAQLQLEHQQHMEG--PSLIHVGTNTEDVNEIAKVQEQL---KQELNDEIKDVNVKDLIE 503
            + ++++E+ +  +    SL       ++ +E+ K+QE      ++L + I+D+  K  I+
Sbjct: 1320 LERIEMENLELAQKLQASLEETTCVAKERDELTKIQEAFYIEMEQLKETIRDLRAK--IQ 1377

Query: 504  KLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEE 563
            +L++ +EQI  + +E    N++  K+K   +LK + M K      ++S  N E   L ++
Sbjct: 1378 ELEAKQEQIFNVREE---DNEDQEKMKEMEQLKEQLMSKE-SILERISLENLE---LAQK 1430

Query: 564  LHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQK 623
            L    ++   + EE+  L            I+  ++   IE + L ET    I  L ++ 
Sbjct: 1431 LQASLEETTSVAEERDELT----------KIKEALH---IERDQLKET----IRDLRAKD 1473

Query: 624  FDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIE 683
             ++ +EL I Q    E ++ +  + +  S++   E  S  L+E+I  L  +++++  V E
Sbjct: 1474 LEIQEELRIAQMSLKEHQETVDKLKECISEKEDIEKTSAQLQEKIQELQTNQEQMFSVRE 1533

Query: 684  NLKLDKEQLYGTIKDLENDKEDIMNK---LQNYIQENMDLTDKLEKMSAEKISELLAKIN 740
             +   +E     IK++E  KE +M+K   L+    EN++L  KL+  S E+I+ + AK  
Sbjct: 1534 EINKTQEN----IKEVEQLKEQLMSKESSLERIEMENLELAQKLQA-SLEEINSV-AK-E 1586

Query: 741  HEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLER--K 798
             +E +KIQ  F I     ERD   E I    +K +    + E+   V E+   + E+  +
Sbjct: 1587 RDELTKIQEAFYI-----ERDQLKEAIRDLRAKIQELESKQEQMFNVREEDNEAQEKMKE 1641

Query: 799  ADQLGSYLQEKQKAYSEYTIQEDELVNRL--------AVLMDHDRVVE-KQLLEIEHEN- 848
             +QL   L  K+      +++  EL  +L        +V  + D + + K+ L IE +  
Sbjct: 1642 MEQLKEQLISKESTLERISLENLELAQKLQASLEETTSVAEERDELTKIKEALHIERDQL 1701

Query: 849  ----KELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLE 904
                ++L+ K+  + EE +  Q SL + Q+  + L E  +  +  + E T  Q Q +DLE
Sbjct: 1702 KETIRDLRAKDLEIQEELRIAQKSLKEHQETVDKLKECISEKE--DVEKTSAQLQEKDLE 1759

Query: 905  SNLK-RITH----EHQTLI------VQKKKEIEDLEIEFNTQI-ESAIRDKKVLNEKYEK 952
            +  + RI      EHQ  +      + +K+++E    +   +I E   + K++ N + E 
Sbjct: 1760 TQEELRIAQKSLKEHQETVDKLKECISEKEDVEKTRAQLQEKIQELESKQKQMFNVREED 1819

Query: 953  N-----IEYVTQLEAQLQEYKNNIENLNM-NVEELNKMNLELIDK-HVQKQQTQSPDYTE 1005
            N     ++ + QL+ QL   +  +E +++ N+E   K+   L +   V +++ +     E
Sbjct: 1820 NEAQEKMKEMEQLKEQLISKEFTLERISLENLELAQKLQASLEETTSVAEERDELTKIKE 1879

Query: 1006 -------QYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFT---- 1054
                   Q    I  L A   +  EE+      + + Q +   +      K+AQ +    
Sbjct: 1880 ALHIERDQLKKTIRDLRAKGLETQEELRIAQMGLKDHQETIDRLKECVSEKVAQVSKNQE 1939

Query: 1055 ----TKLENME--EEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPK 1108
                TK E  E  +E+Q   +Q+++ ++ N E++  V E +   K+LK  + T E    +
Sbjct: 1940 AFEKTKAELQEKIQELQEKKEQVVNVREENSEVEEKVIEIEQLKKQLKTKECTLER--IE 1997

Query: 1109 TEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTEL 1168
             E + ++  ++   ++   V              K+Q  E F  E   L+E    L  + 
Sbjct: 1998 MENLELAQKLQASLEETTCV------TKERDELTKIQ--EAFYIEMEQLKETIRDLRAKN 2049

Query: 1169 QECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAV 1228
            Q+   +++++E      T    + Q  I  LK K  ++N           EL+   +   
Sbjct: 2050 QQKPKELVKMEA-----TARKDIKQHPIESLKEKCSKIN-----------ELQKKYTMME 2093

Query: 1229 DQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFES-KYEQLLDSVQSSTQEETNKIV 1287
            ++ GF    L K  +  ++A   + E +++V+ S + + +  + ++ + +S +   N + 
Sbjct: 2094 NRCGF----LSKLSVDLKKAFESQNELQVKVRASLYHTPQLTKAVEKILASNRRCNNDLH 2149

Query: 1288 TMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEI 1322
            +    T +  KL+   + +  L++++   +N+ ++
Sbjct: 2150 SSS--TCILRKLEGVLKRVVGLRKEHHTTVNKFQM 2182



 Score =  120 bits (290), Expect = 3e-25
 Identities = 277/1385 (20%), Positives = 596/1385 (43%), Gaps = 145/1385 (10%)

Query: 319  ANMTELTKKIELLEHLNCQIRQT-NKELE-NKLATMGTESKAVSSPSKKGSPLIS----- 371
            AN   L    E L+  N +I Q  N++LE  +  T+  E +++     +   +++     
Sbjct: 504  ANFDNLVLDYEQLQIKNAEIEQKLNEKLELEEFVTL--EMQSIKEQEVRNHEILNIMKHE 561

Query: 372  RKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEK 431
             K  +++ ++  S  SQL  E   Q  +K +    I  +E+ +   + + + +E    ++
Sbjct: 562  DKDDQDSENEQNSK-SQLLKEKEEQIKEKFLELQLIKNIELDLY-YDGEKIYEELKHLKQ 619

Query: 432  DTXXXXXXXXXXGKDTLIAQLQ-LEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELN 490
                         K+T   + + LE ++ M+   L       E  N +   Q QL QE  
Sbjct: 620  SLCDTETIALDAQKETAFLKCENLELKEKMK--ELSSQCKQLEKDNHL--YQSQL-QERR 674

Query: 491  DEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKV 550
            D  K     DL ++L+SA  +IT+L   I+      + +    + K+K +QK +D   K 
Sbjct: 675  DSSKRRQA-DLEKELQSAFSEITRLTSIIEGKYPKDVLLTVELERKVKDLQKDLDKAIKE 733

Query: 551  SDSNKEIVRLTEELHHLSQKVAELEEEK--GNLQLHLVDYDSGRMIESDVYK--KMIEME 606
            + + ++ +    EL  L  ++  L++E+   + +L+L+  +  ++    +YK  ++ E+ 
Sbjct: 734  NATLQKEINTLSELKSLPTELEILKKERLEKSEELNLIIAEKDKLRAEIMYKDNRLQELL 793

Query: 607  NLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLE- 665
            +  E   + ++  ++      QE    +Q + E E     + + + +++  +I++V +E 
Sbjct: 794  DEIEKSKEELAAAQATHQTTTQEFQDFKQYHGEFEQNYFTVLE-EIEKMKHQIRTVSVEA 852

Query: 666  EQI-----DALSASKKE----LALVIENL-----KLDKEQLYGTIKDLENDKEDIMNKLQ 711
             +I     D +S   KE    L  V E L     KL+ E+L G    L   +E+    L 
Sbjct: 853  HEIALDFDDLVSEPTKEVREKLLEVREQLCKAQQKLE-ERLSGRRSSLRTSEEE-TQFLP 910

Query: 712  NYIQENMDLTD-KLEKMSAEKISELLAKINHE---EQSKIQTQFGIDAKIQER-DLYIEN 766
              + E++ ++    EK + E+  +L  +   E   ++    + +  D   QE    Y E+
Sbjct: 911  KSLHEHLQVSSGTCEKDAPEQFPKLPFQTKEEQPRQELHAASHWSTDKGTQEELRNYSES 970

Query: 767  IESELSKYKSRI-CRLEESIAV---MEDRRYSLERKADQL--GSYLQEKQKAYSEYTIQE 820
             + + +K  S +  RL E   V    E+    L+ K  +L  G  L+  +        ++
Sbjct: 971  HKCQDTKDSSSMPTRLSEESGVKGIQEEALDELQGKTVKLNEGQNLESPRNLVPLPDYEK 1030

Query: 821  D-ELV---NRLAVLMDHDRVVEKQLLEIEHENK----ELQKKNQILLEENQNLQISLSDM 872
            D EL+    +++ L+     +++ L  +  E      +L++   + +E  + L+   + +
Sbjct: 1031 DNELLQQQRKISSLIQEKNQLQQMLECVTAEKNQLKTDLEENIGMSIENQEELRNIGAAL 1090

Query: 873  QQHYNALVEKANRTDLAESESTKYQTQLRDLESNL-KRI--THEHQTLIVQKKKEIEDLE 929
            ++   A++++  +T   E E  + Q +L D E  L K+I    E +  ++  +KE+ + +
Sbjct: 1091 KKQQEAVLKERRKTAEKEGELVRTQERLADTEEKLNKKIQELQEKENQMLNVRKEVIEAQ 1150

Query: 930  IEFN--TQIESAIRDKKVLNEKYE-KNIEYVTQLEAQLQEYKNNIENLN--MNVEELNKM 984
             + N   QI + +  K    E+ E +N++   +L+A L++  +  + +N     +   ++
Sbjct: 1151 EKVNEMEQIRNQLESKNSTLERVEIENLKLAQKLQASLEQTSSITQEINEFKKTQVALQL 1210

Query: 985  NLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVS 1044
              + + +++++  T+  +  E    E+      LK   E I  L + ++      ++ VS
Sbjct: 1211 ERDQLKENIKEVVTKGLETQE----ELRIAQMGLKDHQETIDRLKECVSEK----VAQVS 1262

Query: 1045 DYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFE- 1103
              +    +   +L+   +E+Q   +Q+++ ++ N E++  V E +   K+LK  + T E 
Sbjct: 1263 KNQEAFEKTKAELQEKIQELQEKKEQVVNVREENSEVEEKVIEIEQLKKQLKTKECTLER 1322

Query: 1104 MNIPKTE-GMIISSTIEPMSDDANNVDXXXXXXXXXXXXLK-----VQEEEEFIQERSVL 1157
            + +   E    + +++E  +  A   D            ++     +++    IQE    
Sbjct: 1323 IEMENLELAQKLQASLEETTCVAKERDELTKIQEAFYIEMEQLKETIRDLRAKIQELEAK 1382

Query: 1158 QEQSAKLNTELQECYTKIIQLETLNTELTGHDVV-------NQEQINQLKSKLEQ----- 1205
            QEQ   +  E  E   K+ ++E L  +L   + +       N E   +L++ LE+     
Sbjct: 1383 QEQIFNVREEDNEDQEKMKEMEQLKEQLMSKESILERISLENLELAQKLQASLEETTSVA 1442

Query: 1206 ------------LNTENDNLLSTVAELRSS---------ISSAVDQRGFEIAELWKQHLA 1244
                        L+ E D L  T+ +LR+          I+    +   E  +  K+ ++
Sbjct: 1443 EERDELTKIKEALHIERDQLKETIRDLRAKDLEIQEELRIAQMSLKEHQETVDKLKECIS 1502

Query: 1245 QREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKI-VTMEQVTSLQNKLQDKE 1303
            ++E D +KT  +L+ ++   ++  EQ+      S +EE NK    +++V  L+ +L  KE
Sbjct: 1503 EKE-DIEKTSAQLQEKIQELQTNQEQMF-----SVREEINKTQENIKEVEQLKEQLMSKE 1556

Query: 1304 EHLRNLQEKYADVINQIEILRSEI------EDEKVAFXXXXXXXXXXXXXXXXDLRTENQ 1357
              L  ++ +  ++  +++    EI       DE                    DLR + Q
Sbjct: 1557 SSLERIEMENLELAQKLQASLEEINSVAKERDELTKIQEAFYIERDQLKEAIRDLRAKIQ 1616

Query: 1358 SYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIY 1417
              +  QEQ + N+ EE+ + ++              + +  E   LE    LEL  ++  
Sbjct: 1617 ELESKQEQ-MFNVREEDNEAQEKMKEMEQLKEQLISKESTLERISLE---NLEL--AQKL 1670

Query: 1418 QKTHEYTITLTQRNDEFENVRQQL-VEYEKRIEDLTYEKESELAI---LRLKMHENANHY 1473
            Q + E T ++ +  DE   +++ L +E ++  E +   +  +L I   LR+       H 
Sbjct: 1671 QASLEETTSVAEERDELTKIKEALHIERDQLKETIRDLRAKDLEIQEELRIAQKSLKEHQ 1730

Query: 1474 ETMQKESE-IERVKLIEELNVKITE-SVSLNKQVAELNKAL---EEEVAKTNEMQTALEN 1528
            ET+ K  E I   + +E+ + ++ E  +   +++    K+L   +E V K  E  +  E+
Sbjct: 1731 ETVDKLKECISEKEDVEKTSAQLQEKDLETQEELRIAQKSLKEHQETVDKLKECISEKED 1790

Query: 1529 QEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKEL-LDAVPRA 1587
             E     L ++I  L++  +     +++  + A +  +  ++  +  ++KE  L+ +   
Sbjct: 1791 VEKTRAQLQEKIQELESK-QKQMFNVREEDNEAQEKMKEMEQLKEQLISKEFTLERISLE 1849

Query: 1588 ELDLA 1592
             L+LA
Sbjct: 1850 NLELA 1854



 Score =  113 bits (272), Expect = 4e-23
 Identities = 236/1237 (19%), Positives = 512/1237 (41%), Gaps = 107/1237 (8%)

Query: 49   ERQIKFERAQKCL-ENAALVSKRIKEHRKATAELLGR-PFVPGISESLANTLKQKEILME 106
            + Q   +R ++C+ E  A VSK  +   K  AEL  +   +    E + N  ++   + E
Sbjct: 1242 DHQETIDRLKECVSEKVAQVSKNQEAFEKTKAELQEKIQELQEKKEQVVNVREENSEVEE 1301

Query: 107  KIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNALSVLQ---V 163
            K+ + ++L K+  T                   Q   +   +   KE+D    + +   +
Sbjct: 1302 KVIEIEQLKKQLKTKECTLERIEMENLELAQKLQ-ASLEETTCVAKERDELTKIQEAFYI 1360

Query: 164  KMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQE 223
            +M+ ++ TI DL+ KI E    +EAK +                    E  K+Q+   + 
Sbjct: 1361 EMEQLKETIRDLRAKIQE----LEAKQEQI-FNVREEDNEDQEKMKEMEQLKEQLMSKES 1415

Query: 224  NFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXX 283
                +  E  +  Q+L   +E         +E  K+ EA   E   +  +  ++L     
Sbjct: 1416 ILERISLENLELAQKLQASLEETTSVAEERDELTKIKEALHIERD-QLKETIRDLRAKDL 1474

Query: 284  XXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNK 343
                         K+  E   + K  I EK  +E  +  +L +KI+ L+    Q+    +
Sbjct: 1475 EIQEELRIAQMSLKEHQETVDKLKECISEKEDIEKTS-AQLQEKIQELQTNQEQMFSVRE 1533

Query: 344  ELENKLATMG-TESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKI 402
            E+      +   E       SK+ S           A K+++   +++S    +D   KI
Sbjct: 1534 EINKTQENIKEVEQLKEQLMSKESSLERIEMENLELAQKLQASLEEINSVAKERDELTKI 1593

Query: 403  N----------KNEIAKLEMVIQSLNK------DLVDKEYVISEKDTXXXXXXXXXXGKD 446
                       K  I  L   IQ L        ++ +++    EK             K+
Sbjct: 1594 QEAFYIERDQLKEAIRDLRAKIQELESKQEQMFNVREEDNEAQEKMKEMEQLKEQLISKE 1653

Query: 447  TLIAQLQLEHQQHMEG--PSLIHVGTNTEDVNEIAKVQEQL---KQELNDEIKDVNVKDL 501
            + + ++ LE+ +  +    SL    +  E+ +E+ K++E L   + +L + I+D+  KDL
Sbjct: 1654 STLERISLENLELAQKLQASLEETTSVAEERDELTKIKEALHIERDQLKETIRDLRAKDL 1713

Query: 502  I--EKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVR 559
               E+L+ A++ + +  + +D   + + + +   K   +  +K ++   ++  + K +  
Sbjct: 1714 EIQEELRIAQKSLKEHQETVDKLKECISEKEDVEKTSAQLQEKDLETQEELRIAQKSLKE 1773

Query: 560  LTEELHHLSQKVAELEE-EKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISL 618
              E +  L + ++E E+ EK   QL     +  + +ES    K  +M N+ E        
Sbjct: 1774 HQETVDKLKECISEKEDVEKTRAQLQ----EKIQELES----KQKQMFNVREE------- 1818

Query: 619  LESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKEL 678
             +++  + ++E+  L+++    E  L  IS L++ ++  ++++  LEE   +++  + EL
Sbjct: 1819 -DNEAQEKMKEMEQLKEQLISKEFTLERIS-LENLELAQKLQA-SLEETT-SVAEERDEL 1874

Query: 679  ALVIENLKLDKEQLYGTIKDLENDKEDIMNKL---QNYIQENMDLTDKLEKMSAEKISEL 735
              + E L ++++QL  TI+DL     +   +L   Q  ++++ +  D+L++  +EK++++
Sbjct: 1875 TKIKEALHIERDQLKKTIRDLRAKGLETQEELRIAQMGLKDHQETIDRLKECVSEKVAQV 1934

Query: 736  LAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSL 795
                   E++K + Q  I  ++QE+   + N+  E S+ + ++  +E+    ++ +  +L
Sbjct: 1935 SKNQEAFEKTKAELQEKIQ-ELQEKKEQVVNVREENSEVEEKVIEIEQLKKQLKTKECTL 1993

Query: 796  ERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKN 855
            ER   +     Q+ Q +  E T    E  + L  + +   +  +QL E     ++L+ KN
Sbjct: 1994 ERIEMENLELAQKLQASLEETTCVTKER-DELTKIQEAFYIEMEQLKETI---RDLRAKN 2049

Query: 856  QILLEENQNLQISL-SDMQQH-YNALVEKANRTDLAESESTKYQTQ---LRDLESNLKRI 910
            Q   +E   ++ +   D++QH   +L EK ++ +  + + T  + +   L  L  +LK+ 
Sbjct: 2050 QQKPKELVKMEATARKDIKQHPIESLKEKCSKINELQKKYTMMENRCGFLSKLSVDLKKA 2109

Query: 911  THEHQTLIVQKKKEIEDLEIEFNTQIESAIR-DKKVLNEKYEKNIEYVTQLEAQLQ---- 965
                  L V+ +  +     +    +E  +  +++  N+ +  +   + +LE  L+    
Sbjct: 2110 FESQNELQVKVRASLYHTP-QLTKAVEKILASNRRCNNDLHSSSTCILRKLEGVLKRVVG 2168

Query: 966  ---EYKNNIENLNMN-VEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQ- 1020
               E+   +    M+ + E  + N  L+     +Q +Q             K+N  ++Q 
Sbjct: 2169 LRKEHHTTVNKFQMDLIREAERQNELLVKTQHLQQHSQGGSLESSGYKLSQKMNLHVEQI 2228

Query: 1021 -KD--------EEIIALNQKINNAQ---VSYMSM-------VSDYESKLAQFTTKLENME 1061
             KD          +IA  Q++ NA+   + ++ +       V   +  + +   ++ N+ 
Sbjct: 2229 LKDVSETQNDVHNMIAEFQQLLNAKKEIILFLDVCLNTHFDVECLKKVIQEENDRIVNVN 2288

Query: 1062 EEMQRVSKQLLDSKQHNEELQIL-VREQDDQIKELKET--KLTFEMNIPKTEGMIISSTI 1118
                   K +++     E+  I+  +E + +++++KE   +L  ++   +T    ++  +
Sbjct: 2289 NSYCNKIKAIINESSEFEDKSIIECKEWEHELRQMKEENEELVKKLQTTQTPPTALND-L 2347

Query: 1119 EPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQL 1178
            + +S      D             K      F +E   L+ +  KLN E      K  + 
Sbjct: 2348 DALSGGEKKHDLKLRHTGRTTKDAKATLGAVFSKEIDDLKMKLVKLNMEKMNESKKFEKE 2407

Query: 1179 ETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLS 1215
                T +  H   N+E I+QLK +L +    ND  +S
Sbjct: 2408 IASKTAIIEH---NEEIISQLKERLRRAQQCNDTSMS 2441



 Score = 60.1 bits (139), Expect = 5e-07
 Identities = 118/606 (19%), Positives = 248/606 (40%), Gaps = 48/606 (7%)

Query: 743  EQSKIQTQFGIDAKIQERDLYIENI---ESELSKYKSRICRLEESIAVMEDRRYSLERKA 799
            E++    QF   AK  +   ++  +   E+ L +Y+  I  L++ +  +         + 
Sbjct: 314  EETLSTLQFASTAKYMKNTPHVNEVLDDEALLKRYRKEIIDLKKQLEEVSSETRVQAMEK 373

Query: 800  DQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILL 859
            DQL   L+EK        +Q D++ N   +L+    +  +Q L+ + + +      ++  
Sbjct: 374  DQLAQLLEEKDLLQK---VQNDKIQNLTQMLVTSSSITIQQDLKAKRKRRVTWCPGKM-- 428

Query: 860  EENQNLQISLSDMQQHYNALVEKANRTDL-AESESTKYQTQLRDLESNLKRITHEHQTLI 918
              N+   I   D       LV K+ +  L   +++ +      D+ SN      E +   
Sbjct: 429  --NKMKDIGYMDDFDITKTLVAKSVKPALPIIADTDESMCSEFDIFSNTLETISEMEWNP 486

Query: 919  VQKKKEIEDLEIEFNT---QIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLN 975
              K  + E+++ E N+     ++ + D + L  K    IE     + +L+E+   +E  +
Sbjct: 487  ATKLNQ-ENVQSELNSLRANFDNLVLDYEQLQIK-NAEIEQKLNEKLELEEFV-TLEMQS 543

Query: 976  MNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEI---IALNQKI 1032
            +  +E+    +  I KH  K    S        NE N  + LLK+K+E+I       Q I
Sbjct: 544  IKEQEVRNHEILNIMKHEDKDDQDSE-------NEQNSKSQLLKEKEEQIKEKFLELQLI 596

Query: 1033 NNAQVS-YMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQ 1091
             N ++  Y      YE +L      L + E       K+    K  N EL+  ++E   Q
Sbjct: 597  KNIELDLYYDGEKIYE-ELKHLKQSLCDTETIALDAQKETAFLKCENLELKEKMKELSSQ 655

Query: 1092 IKELK------ETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQ 1145
             K+L+      +++L    +  K     +   ++    +   +             L V+
Sbjct: 656  CKQLEKDNHLYQSQLQERRDSSKRRQADLEKELQSAFSEITRLTSIIEGKYPKDVLLTVE 715

Query: 1146 EEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQ 1205
             E + +++     +++ K N  LQ+    + +L++L TEL   +++ +E++ +   +L  
Sbjct: 716  LERK-VKDLQKDLDKAIKENATLQKEINTLSELKSLPTEL---EILKKERLEK-SEELNL 770

Query: 1206 LNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFE 1265
            +  E D L + +    + +   +D+      E  K+ LA  +A  Q T  E +     + 
Sbjct: 771  IIAEKDKLRAEIMYKDNRLQELLDE-----IEKSKEELAAAQATHQTTTQEFQ-DFKQYH 824

Query: 1266 SKYEQLLDSVQSSTQEETNKIVTME-QVTSLQNKLQD-KEEHLRNLQEKYADVINQIEIL 1323
             ++EQ   +V    ++  ++I T+  +   +     D   E  + ++EK  +V  Q+   
Sbjct: 825  GEFEQNYFTVLEEIEKMKHQIRTVSVEAHEIALDFDDLVSEPTKEVREKLLEVREQLCKA 884

Query: 1324 RSEIED 1329
            + ++E+
Sbjct: 885  QQKLEE 890



 Score = 54.0 bits (124), Expect = 3e-05
 Identities = 103/553 (18%), Positives = 240/553 (43%), Gaps = 63/553 (11%)

Query: 813  YSEYTIQEDELVNRLAVLMDHDRVV---EKQLLEIEHENK-ELQKKNQI--LLEENQNLQ 866
            Y + T   +E+++  A+L  + + +   +KQL E+  E + +  +K+Q+  LLEE   LQ
Sbjct: 328  YMKNTPHVNEVLDDEALLKRYRKEIIDLKKQLEEVSSETRVQAMEKDQLAQLLEEKDLLQ 387

Query: 867  ISLSDMQQHYNALVEKANRTDLAESESTKYQTQLR---DLESNLKRITHEH-----QTLI 918
               +D  Q+   ++  ++   + +    K + ++       + +K I +       +TL+
Sbjct: 388  KVQNDKIQNLTQMLVTSSSITIQQDLKAKRKRRVTWCPGKMNKMKDIGYMDDFDITKTLV 447

Query: 919  VQKKKE----IEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQ--LEAQLQEYKNNIE 972
             +  K     I D +    ++ +      + ++E        + Q  ++++L   + N +
Sbjct: 448  AKSVKPALPIIADTDESMCSEFDIFSNTLETISEMEWNPATKLNQENVQSELNSLRANFD 507

Query: 973  NLNMNVEELNKMNLELIDKHVQKQQTQS------PDYTEQYINEINKLNALLKQKDEEII 1026
            NL ++ E+L   N E+  K  +K + +           EQ +     LN ++K +D++  
Sbjct: 508  NLVLDYEQLQIKNAEIEQKLNEKLELEEFVTLEMQSIKEQEVRNHEILN-IMKHEDKD-- 564

Query: 1027 ALNQKINNAQVSYMSMVSDYESKLAQFTTKLE---NMEEEMQRVSKQLLDSKQHNEELQI 1083
              +Q   N Q S   ++ + E ++ +   +L+   N+E ++    +++ +  +H +  Q 
Sbjct: 565  --DQDSENEQNSKSQLLKEKEEQIKEKFLELQLIKNIELDLYYDGEKIYEELKHLK--QS 620

Query: 1084 LVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLK 1143
            L   +   +   KET         K E + +   ++ +S     ++              
Sbjct: 621  LCDTETIALDAQKETAFL------KCENLELKEKMKELSSQCKQLEKDNHLY-------- 666

Query: 1144 VQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKL 1203
               + +  + R   + + A L  ELQ  +++I +L ++       DV+      +L+ K+
Sbjct: 667  ---QSQLQERRDSSKRRQADLEKELQSAFSEITRLTSIIEGKYPKDVL---LTVELERKV 720

Query: 1204 EQLNTENDNLLSTVAELRSSISSAVDQRGF--EIAELWKQHLAQ-READFQKTEHE-LRV 1259
            + L  + D  +   A L+  I++  + +    E+  L K+ L +  E +    E + LR 
Sbjct: 721  KDLQKDLDKAIKENATLQKEINTLSELKSLPTELEILKKERLEKSEELNLIIAEKDKLRA 780

Query: 1260 QLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQ 1319
            ++   +++ ++LLD ++ S +E      T +  T    + QD +++    ++ Y  V+ +
Sbjct: 781  EIMYKDNRLQELLDEIEKSKEELAAAQATHQTTT---QEFQDFKQYHGEFEQNYFTVLEE 837

Query: 1320 IEILRSEIEDEKV 1332
            IE ++ +I    V
Sbjct: 838  IEKMKHQIRTVSV 850


>UniRef50_UPI00004995B4 Cluster: myosin heavy chain; n=1; Entamoeba
            histolytica HM-1:IMSS|Rep: myosin heavy chain - Entamoeba
            histolytica HM-1:IMSS
          Length = 1312

 Score =  139 bits (336), Expect = 7e-31
 Identities = 256/1274 (20%), Positives = 517/1274 (40%), Gaps = 123/1274 (9%)

Query: 396  QDTDKKINKNEIAKLEMVIQSLNKDLVDKE--------YVISEKDTXXXXXXXXXXGKDT 447
            Q+ + K+ KNE+   E VI++  K+L + E         ++ EK+            KD 
Sbjct: 62   QNENAKL-KNELQTKEDVIKNYQKELTEVEEKNKGVDDRILEEKEKRKSAELELENKKDD 120

Query: 448  LI-AQLQLEH-QQHMEG------PSLIHVGTNTEDVNE---IAKVQEQLKQELNDEIKDV 496
            ++  Q  + + +Q++ G           + T T+  N+     KV ++ K++L  E+ DV
Sbjct: 121  ILELQAMVSNLKQNLAGLQQELKNKEEEIITETDKSNKALAAQKVYQEQKEKLESELADV 180

Query: 497  NVK------DLIEKLKSAE------EQITQ-----------LNDEIDAANKNMIKVKSNH 533
             +K      +L+     A+      E ITQ            + +ID+ N  + +V+ + 
Sbjct: 181  KIKLDTTQQELVATQARADGNEKEIEDITQEQNGWIRQAKEASKQIDSLNTELEEVEKDL 240

Query: 534  KLKLKQMQKTIDNFSK----VSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYD 589
              ++K+   T  +  K    +  SN +I +L E+   L +  AE +E K      +V   
Sbjct: 241  DDEIKRHTATKADLEKTKNDLESSNNQINKLKEQ---LEKTKAEKDENKNVADQEVVTRK 297

Query: 590  SGRMIESDVYKKMIEMENLAETRLKAISLLE-------SQKFDLVQE-------LHILQ- 634
            +     SD+ KK+   +   ET    ++ L+        +K DL +E       L +LQ 
Sbjct: 298  AVERKVSDLEKKVEGYKTDYETSQNLVNDLQVKLRAVTKEKEDLEKEYSSGNNILEVLQQ 357

Query: 635  --QKYDEVEDKLADISQLQSDQVCSEIKSV-HLEEQIDALSASKKELALVIENLKLDKEQ 691
              QK DE   KL D    Q+ +    ++ +  LE    AL+    EL L ++  K    +
Sbjct: 358  SKQKGDEEIIKLHDDLAEQAKKTTDAMRDIKQLEYDKVALNGEITELNLELDKQKQLVTK 417

Query: 692  LYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELL--AKINHEEQSKIQT 749
            L   +K L++DKE     +++   EN  LT+++         EL+   K+  E Q+   T
Sbjct: 418  LQQEVKQLQDDKELNEQDIRDAGFENKKLTNQINDAKEAMDKELMKEEKLKQEIQALKDT 477

Query: 750  QFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEK 809
                D +  + +  I N E  + + ++    L E++      + +  RK +Q+ + L+EK
Sbjct: 478  IAKNDEEHDKLESDINNNEKTIKQLQNANKVLTENLENCTRDKEAALRKKEQVETDLKEK 537

Query: 810  QKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISL 869
             + Y     ++ EL ++L  L   +  + + +  I  +     K  + LL++ Q     L
Sbjct: 538  SEEYDALNEKQRELNSQLVTLQKENAGLNETVGTISPD----LKNTKALLKQTQK---EL 590

Query: 870  SDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLE 929
             D +     L          + E  +    + +LE   K++  E   +  +  KE E+L 
Sbjct: 591  KDAKDKIEGLTLDNEDLKKKQKEILEGHVSMEELEDYEKQLQREVAKIKQKSDKEAEELL 650

Query: 930  IEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELI 989
               +   +   +   ++N+ Y++N++ +TQ   ++++ KN  E   + V++  K   E I
Sbjct: 651  DALDASDKKNEKLNNIINQ-YKENLDKLTQEHEEMEKAKNTAEKRVIIVQQDVKDKEETI 709

Query: 990  DKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESK 1049
             K ++K +    D        I  L + +   +   + ++  +N A  SY   + D    
Sbjct: 710  AK-LEKDKNTLKD-------RITDLESRIDGLEGGNVDVSVVVNAATESYKKQIDDLNKT 761

Query: 1050 LAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKT 1109
            +     + +++ +E++ +   ++D K   E  +  V +  D++  + +   + +  +   
Sbjct: 762  IQDAKDQEKDLRDEIKDLRLDIVDLKGELESKEQEVNKAGDKLVLIDDENQSLKQTVND- 820

Query: 1110 EGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQE---RSVLQEQSAKLNT 1166
                +   I+   D+ N +              + + EE+  QE      LQ++   +NT
Sbjct: 821  ----LKLKIKQSGDEKNELTMKIKYMELQMSAPQKEIEEKLNQEVMKNQDLQDEITSINT 876

Query: 1167 ELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSS--- 1223
            +L E   K    E    E+           N L++  ++   +   L + VA+L +    
Sbjct: 877  QLAEAVEKRKASEAALEEMKEQMDGKIRNSNDLEATYQECFNKKTELENKVADLENQLEI 936

Query: 1224 ISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEET 1283
            I  +++++  +IA+L  Q L+    D    +          ++   Q LD      Q ++
Sbjct: 937  IKDSIEEKDDKIADLQSQ-LSSNSNDAVANDKLGDAMQLKIDTINRQYLDLKSKYDQLKS 995

Query: 1284 NKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXX 1343
            + ++ + +   ++ +L   +E +  ++  Y     +IE L+ ++   K            
Sbjct: 996  DNLMVLSEKEDIEEELSSVKEEMTKMEGDYRKKAAEIEKLKHDVNFTK----QVTGDDAN 1051

Query: 1344 XXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVL 1403
                   D     + Y  + E S   +  +N QL+K              ++   E ++ 
Sbjct: 1052 DLEKLQEDYDQLQEDYDDLMEDSDA-LTAKNQQLEKRVTELTDEVEISQDKIKALEKQLR 1110

Query: 1404 ELTHQLELKDSEIYQKTHEYTITLTQRND----EFENVRQQLVEYEKRIEDL---TYEKE 1456
            +  ++LE    +      +Y + +   ND    E +  R ++ E E+ ++ L     E++
Sbjct: 1111 KQNNELEDHADDAENADDDY-VRMKADNDKIRKERDEYRNKITEMEENMDQLKKTITEQD 1169

Query: 1457 SELAILRLKMHENANHYETMQKESEIERVKLIEELNVKI----TESVSLNKQVAELNKAL 1512
             ++  LR    E A   +   K+ E E  K  EEL  K     T+     KQ  EL + +
Sbjct: 1170 IKITELRGGNGEEALKIKAQIKQIEEENDKEKEELLAKAQQFKTKMNKFKKQAQELAEKV 1229

Query: 1513 EE-----EVAKTNEMQTALENQEIEIVTLNDEITNLQNMV---RASSSKIQKHVSFASDT 1564
            E+     E AK +       + + +I  L DEI ++   +   +  SS++Q+ V+     
Sbjct: 1230 EDLEGQLEKAKGSAAAAGASDLKSKIKDLQDEIEDVNQKLSSEKEKSSRLQRKVTSLESD 1289

Query: 1565 KQGRDEQLDNTMNK 1578
             Q +DEQ+     K
Sbjct: 1290 SQDKDEQIAKLKKK 1303



 Score =  126 bits (304), Expect = 5e-27
 Identities = 244/1230 (19%), Positives = 518/1230 (42%), Gaps = 113/1230 (9%)

Query: 153  EKDNALSVLQVKMKIMETTILDLQEKI-NEKDQIIEAKNKATTXXXXXXXXXXXXXXXXX 211
            +KD+ L  LQ  +  ++  +  LQ+++ N++++II   +K+                   
Sbjct: 117  KKDDILE-LQAMVSNLKQNLAGLQQELKNKEEEIITETDKSNKALAAQKVYQEQKEKLES 175

Query: 212  E--DTKQQMTKMQENFIAMEAEWKDEKQRLLKDI-ESKDVRISSLEEANKLLEAARFEIS 268
            E  D K ++   Q+  +A +A   D  ++ ++DI + ++  I   +EA+K +++   E+ 
Sbjct: 176  ELADVKIKLDTTQQELVATQAR-ADGNEKEIEDITQEQNGWIRQAKEASKQIDSLNTELE 234

Query: 269  LEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKI 328
                 L  E+++              L   + + + + K ++E+  + +  N     +++
Sbjct: 235  EVEKDLDDEIKRHTATKADLEKTKNDLESSNNQIN-KLKEQLEKTKAEKDENKNVADQEV 293

Query: 329  ELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQ 388
               + +  ++    K++E       T    V+    K   +   K          +   +
Sbjct: 294  VTRKAVERKVSDLEKKVEGYKTDYETSQNLVNDLQVKLRAVTKEKEDLEKEYSSGNNILE 353

Query: 389  LSSETLNQDTDKKINK--NEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKD 446
            +  ++  Q  D++I K  +++A+         +D+   EY     +            + 
Sbjct: 354  VLQQS-KQKGDEEIIKLHDDLAEQAKKTTDAMRDIKQLEYDKVALNGEITELNLELDKQK 412

Query: 447  TLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLK 506
             L+ +LQ E +Q  +   L     N +D+ +     ++L  ++ND  K+   K+L+++ K
Sbjct: 413  QLVTKLQQEVKQLQDDKEL-----NEQDIRDAGFENKKLTNQINDA-KEAMDKELMKEEK 466

Query: 507  SAEEQITQLNDEIDAANKNMIKVKS---NHKLKLKQMQKT----IDNFSKVSDSNKEIVR 559
              +E I  L D I   ++   K++S   N++  +KQ+Q       +N    +   +  +R
Sbjct: 467  LKQE-IQALKDTIAKNDEEHDKLESDINNNEKTIKQLQNANKVLTENLENCTRDKEAALR 525

Query: 560  LTEELH-HLSQKVAE---LEEEKGNLQLHLVDYDSGRM-IESDVYKKMIEMENLAETRLK 614
              E++   L +K  E   L E++  L   LV        +   V     +++N      +
Sbjct: 526  KKEQVETDLKEKSEEYDALNEKQRELNSQLVTLQKENAGLNETVGTISPDLKNTKALLKQ 585

Query: 615  AISLLESQKFDLVQELHI----LQQKYDEVEDKLADISQLQS--DQVCSEIKSV------ 662
                L+  K D ++ L +    L++K  E+ +    + +L+    Q+  E+  +      
Sbjct: 586  TQKELKDAK-DKIEGLTLDNEDLKKKQKEILEGHVSMEELEDYEKQLQREVAKIKQKSDK 644

Query: 663  HLEEQIDALSASKKE---LALVIENLK--LDK-EQLYGTIKDLENDKEDIMNKLQNYIQE 716
              EE +DAL AS K+   L  +I   K  LDK  Q +  ++  +N  E  +  +Q  +++
Sbjct: 645  EAEELLDALDASDKKNEKLNNIINQYKENLDKLTQEHEEMEKAKNTAEKRVIIVQQDVKD 704

Query: 717  NMDLTDKLEKMS---AEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSK 773
              +   KLEK      ++I++L ++I+  E   +     ++A  +     I+++   +  
Sbjct: 705  KEETIAKLEKDKNTLKDRITDLESRIDGLEGGNVDVSVVVNAATESYKKQIDDLNKTIQD 764

Query: 774  YKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDE------LVNRL 827
             K +   L + I   +D R  +     +L S  QE  KA  +  + +DE       VN L
Sbjct: 765  AKDQEKDLRDEI---KDLRLDIVDLKGELESKEQEVNKAGDKLVLIDDENQSLKQTVNDL 821

Query: 828  AVLMDHDRVVEKQL--------LEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNAL 879
             + +      + +L        L++    KE+++K    + +NQ+LQ  ++ +       
Sbjct: 822  KLKIKQSGDEKNELTMKIKYMELQMSAPQKEIEEKLNQEVMKNQDLQDEITSINTQLAEA 881

Query: 880  VEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESA 939
            VEK   ++ A  E  K Q   +   SN    T++       KK E+E+   +   Q+E  
Sbjct: 882  VEKRKASEAA-LEEMKEQMDGKIRNSNDLEATYQE---CFNKKTELENKVADLENQLE-I 936

Query: 940  IRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNI---ENLNMNVEELNKMNLELIDKHVQKQ 996
            I+D   + EK +K  +  +QL +   +   N    + + + ++ +N+  L+L  K+ Q +
Sbjct: 937  IKDS--IEEKDDKIADLQSQLSSNSNDAVANDKLGDAMQLKIDTINRQYLDLKSKYDQLK 994

Query: 997  Q------TQSPDYTEQYIN---EINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYE 1047
                   ++  D  E+  +   E+ K+    ++K  EI  L   +N  +       +D E
Sbjct: 995  SDNLMVLSEKEDIEEELSSVKEEMTKMEGDYRKKAAEIEKLKHDVNFTKQVTGDDANDLE 1054

Query: 1048 SKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIP 1107
                 +    E+ ++ M+      L +K  N++L+  V E  D+++  ++     E  + 
Sbjct: 1055 KLQEDYDQLQEDYDDLME--DSDALTAK--NQQLEKRVTELTDEVEISQDKIKALEKQLR 1110

Query: 1108 KTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTE 1167
            K      ++ +E  +DDA N D            ++ +E +E+  + + ++E   +L   
Sbjct: 1111 KQ-----NNELEDHADDAENADDDYVRMKADNDKIR-KERDEYRNKITEMEENMDQLKKT 1164

Query: 1168 LQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSA 1227
            + E   KI       TEL G    N E+  ++K++++Q+  END     +        + 
Sbjct: 1165 ITEQDIKI-------TELRGG---NGEEALKIKAQIKQIEEENDKEKEELLAKAQQFKTK 1214

Query: 1228 VDQRGFEIAELWKQHLAQREADFQKTEHELRVQ-LSAFESKYEQLLDSVQSSTQE---ET 1283
            +++   +  EL  + +   E   +K +        S  +SK + L D ++   Q+   E 
Sbjct: 1215 MNKFKKQAQEL-AEKVEDLEGQLEKAKGSAAAAGASDLKSKIKDLQDEIEDVNQKLSSEK 1273

Query: 1284 NKIVTMEQ-VTSLQNKLQDKEEHLRNLQEK 1312
             K   +++ VTSL++  QDK+E +  L++K
Sbjct: 1274 EKSSRLQRKVTSLESDSQDKDEQIAKLKKK 1303



 Score =  122 bits (294), Expect = 8e-26
 Identities = 217/1117 (19%), Positives = 470/1117 (42%), Gaps = 85/1117 (7%)

Query: 145  THLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXX 204
            T L    K+ D+ +         +E T  DL+   N+ +++ E   K T           
Sbjct: 231  TELEEVEKDLDDEIKRHTATKADLEKTKNDLESSNNQINKLKEQLEK-TKAEKDENKNVA 289

Query: 205  XXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAAR 264
                   +  +++++ +++     + ++ +  Q L+ D++ K +R  + E+ +   E + 
Sbjct: 290  DQEVVTRKAVERKVSDLEKKVEGYKTDY-ETSQNLVNDLQVK-LRAVTKEKEDLEKEYSS 347

Query: 265  FEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSL--EIANMT 322
                LE   L Q  ++               AK++ +   + K    +K +L  EI  + 
Sbjct: 348  GNNILE--VLQQSKQKGDEEIIKLHDDLAEQAKKTTDAMRDIKQLEYDKVALNGEITELN 405

Query: 323  -ELTKKIELLEHLNCQIRQT--NKEL-ENKLATMGTESKAVSSPSKKGSPLISRKSGRNT 378
             EL K+ +L+  L  +++Q   +KEL E  +   G E+K +++        + ++  +  
Sbjct: 406  LELDKQKQLVTKLQQEVKQLQDDKELNEQDIRDAGFENKKLTNQINDAKEAMDKELMKEE 465

Query: 379  ASKMKSPWSQLSSETLNQDTDK---KINKNE--IAKLEMVIQSLNKDLV----DKEYVIS 429
              K +    + +    +++ DK    IN NE  I +L+   + L ++L     DKE  + 
Sbjct: 466  KLKQEIQALKDTIAKNDEEHDKLESDINNNEKTIKQLQNANKVLTENLENCTRDKEAALR 525

Query: 430  EKDTXXXXXXXXXXGKDTLIA-QLQLEHQQ---HMEGPSLIH-VGTNTEDVNEIAKVQEQ 484
            +K+             D L   Q +L  Q      E   L   VGT + D+     + +Q
Sbjct: 526  KKEQVETDLKEKSEEYDALNEKQRELNSQLVTLQKENAGLNETVGTISPDLKNTKALLKQ 585

Query: 485  LKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTI 544
             ++EL D       KD IE L    E + +   EI   + +M +++   K    Q+Q+ +
Sbjct: 586  TQKELKD------AKDKIEGLTLDNEDLKKKQKEILEGHVSMEELEDYEK----QLQREV 635

Query: 545  DNFSKVSDSN-KEIVRLTEELHHLSQKVAEL-EEEKGNLQLHLVDYDSGRMIESDVYKKM 602
                + SD   +E++   +     ++K+  +  + K NL     +++     ++   K++
Sbjct: 636  AKIKQKSDKEAEELLDALDASDKKNEKLNNIINQYKENLDKLTQEHEEMEKAKNTAEKRV 695

Query: 603  IEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSV 662
            I ++   + + + I+ LE  K  L   +  L+ + D +E    D+S + +    S  K +
Sbjct: 696  IIVQQDVKDKEETIAKLEKDKNTLKDRITDLESRIDGLEGGNVDVSVVVNAATESYKKQI 755

Query: 663  H-LEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLT 721
              L + I      +K+L   I++L+LD   L G ++  E +     +KL     EN  L 
Sbjct: 756  DDLNKTIQDAKDQEKDLRDEIKDLRLDIVDLKGELESKEQEVNKAGDKLVLIDDENQSLK 815

Query: 722  D-----KLE-KMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYK 775
                  KL+ K S ++ +EL  KI + E      Q  I+ K+ +  +  ++++ E++   
Sbjct: 816  QTVNDLKLKIKQSGDEKNELTMKIKYMELQMSAPQKEIEEKLNQEVMKNQDLQDEITSIN 875

Query: 776  SRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDR 835
            +++    E     E     ++ + D       + +  Y E   ++ EL N++A L +   
Sbjct: 876  TQLAEAVEKRKASEAALEEMKEQMDGKIRNSNDLEATYQECFNKKTELENKVADLENQLE 935

Query: 836  VVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTK 895
            +++  + E + +  +LQ +    L  N N  ++   +       ++  NR          
Sbjct: 936  IIKDSIEEKDDKIADLQSQ----LSSNSNDAVANDKLGDAMQLKIDTINR---------- 981

Query: 896  YQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEI--EFNTQIESAIRDKKVLNEKYEKN 953
               Q  DL+S   ++  ++  ++ +K+   E+L    E  T++E   R K    EK + +
Sbjct: 982  ---QYLDLKSKYDQLKSDNLMVLSEKEDIEEELSSVKEEMTKMEGDYRKKAAEIEKLKHD 1038

Query: 954  IEYVTQLEA----QLQEYKNNIENLNMNVEELNKMNLELIDKH--VQKQQTQSPDYTEQY 1007
            + +  Q+       L++ + + + L  + ++L + +  L  K+  ++K+ T+  D  E  
Sbjct: 1039 VNFTKQVTGDDANDLEKLQEDYDQLQEDYDDLMEDSDALTAKNQQLEKRVTELTDEVEIS 1098

Query: 1008 INEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYE---SKLAQFTTKLENMEEEM 1064
             ++I  L   L++++ E+        NA   Y+ M +D +    +  ++  K+  MEE M
Sbjct: 1099 QDKIKALEKQLRKQNNELEDHADDAENADDDYVRMKADNDKIRKERDEYRNKITEMEENM 1158

Query: 1065 QRVSK-------QLLDSKQHNEELQILVREQDDQIKE---LKETKLTFEMNIPKTEGMII 1114
             ++ K       ++ + +  N E  + ++ Q  QI+E    ++ +L  +    KT+    
Sbjct: 1159 DQLKKTITEQDIKITELRGGNGEEALKIKAQIKQIEEENDKEKEELLAKAQQFKTKMNKF 1218

Query: 1115 SSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTK 1174
                + +++   +++                + +  I++   LQ++   +N +L     K
Sbjct: 1219 KKQAQELAEKVEDLEGQLEKAKGSAAAAGASDLKSKIKD---LQDEIEDVNQKLSSEKEK 1275

Query: 1175 IIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTEND 1211
              +L+   T L        EQI +LK K++++  ++D
Sbjct: 1276 SSRLQRKVTSLESDSQDKDEQIAKLKKKIKRMMVDDD 1312



 Score =  104 bits (250), Expect = 2e-20
 Identities = 194/1021 (19%), Positives = 427/1021 (41%), Gaps = 86/1021 (8%)

Query: 575  EEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQ 634
            EE    +Q  + +Y + + I   ++K+  E +  +  + K +   +++  +L Q L  LQ
Sbjct: 4    EEAISIIQSAIKEYCNQKSIWLKLFKEC-EKDLESYHKAKQLDGTKAEVGELEQTLIKLQ 62

Query: 635  QKYDEVEDKLAD----ISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKE 690
             +  +++++L      I   Q +    E K+  ++++I      +K   L +EN K D  
Sbjct: 63   NENAKLKNELQTKEDVIKNYQKELTEVEEKNKGVDDRILEEKEKRKSAELELENKKDDIL 122

Query: 691  QLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQ 750
            +L   + +L+ +   +  +L+N  +E +  TDK  K  A +      K+  E++ K++++
Sbjct: 123  ELQAMVSNLKQNLAGLQQELKNKEEEIITETDKSNKALAAQ------KVYQEQKEKLESE 176

Query: 751  FGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQ 810
               D KI+     ++  + EL   ++R    E+ I  +   +    R+A +    +    
Sbjct: 177  LA-DVKIK-----LDTTQQELVATQARADGNEKEIEDITQEQNGWIRQAKEASKQIDSLN 230

Query: 811  KAYSEYTIQ-EDELVNRLAVLMDHDRVVEKQLLEIEHENKELQK-KNQI---LLEENQNL 865
                E     +DE+    A   D    +EK   ++E  N ++ K K Q+     E+++N 
Sbjct: 231  TELEEVEKDLDDEIKRHTATKAD----LEKTKNDLESSNNQINKLKEQLEKTKAEKDENK 286

Query: 866  QISLSDMQQHYNALVEKANRTDLAESESTKYQTQ---LRDLESNLKRITHEHQTL----- 917
             ++  ++        + ++     E   T Y+T    + DL+  L+ +T E + L     
Sbjct: 287  NVADQEVVTRKAVERKVSDLEKKVEGYKTDYETSQNLVNDLQVKLRAVTKEKEDLEKEYS 346

Query: 918  -------IVQKKKEIEDLEI--------EFNTQIESAIRDKKVLN-EKYEKNIEYVTQLE 961
                   ++Q+ K+  D EI        E   +   A+RD K L  +K   N E +T+L 
Sbjct: 347  SGNNILEVLQQSKQKGDEEIIKLHDDLAEQAKKTTDAMRDIKQLEYDKVALNGE-ITELN 405

Query: 962  AQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKL--NALLK 1019
             +L + K  +  L   V++L   + EL ++ ++    ++   T Q IN+  +     L+K
Sbjct: 406  LELDKQKQLVTKLQQEVKQLQD-DKELNEQDIRDAGFENKKLTNQ-INDAKEAMDKELMK 463

Query: 1020 QK--DEEIIALNQKINNAQVSYMSMVSDY---ESKLAQFTTKLENMEEEMQRVSKQLLDS 1074
            ++   +EI AL   I      +  + SD    E  + Q     + + E ++  ++    +
Sbjct: 464  EEKLKQEIQALKDTIAKNDEEHDKLESDINNNEKTIKQLQNANKVLTENLENCTRDKEAA 523

Query: 1075 KQHNEELQILVREQDDQIKEL--KETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXX 1132
             +  E+++  ++E+ ++   L  K+ +L  ++   + E   ++ T+  +S D  N     
Sbjct: 524  LRKKEQVETDLKEKSEEYDALNEKQRELNSQLVTLQKENAGLNETVGTISPDLKNTKALL 583

Query: 1133 XXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVN 1192
                      ++++ ++ I+  ++  E   K   E+ E +  + +LE    +L       
Sbjct: 584  KQTQK-----ELKDAKDKIEGLTLDNEDLKKKQKEILEGHVSMEELEDYEKQL------- 631

Query: 1193 QEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQK 1252
            Q ++ ++K K ++   E  + L    +    +++ ++Q    + +L ++H    E +  K
Sbjct: 632  QREVAKIKQKSDKEAEELLDALDASDKKNEKLNNIINQYKENLDKLTQEH---EEMEKAK 688

Query: 1253 TEHELRVQLSAFESK-YEQLLDSVQSSTQEETNKIVTME-QVTSLQNKLQDKEEHLRNLQ 1310
               E RV +   + K  E+ +  ++       ++I  +E ++  L+    D    +    
Sbjct: 689  NTAEKRVIIVQQDVKDKEETIAKLEKDKNTLKDRITDLESRIDGLEGGNVDVSVVVNAAT 748

Query: 1311 EKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNI 1370
            E Y   I+ +     + +D++                   +L ++ Q   +  ++ +L I
Sbjct: 749  ESYKKQIDDLNKTIQDAKDQEKDLRDEIKDLRLDIVDLKGELESKEQEVNKAGDKLVL-I 807

Query: 1371 NEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQR 1430
            ++EN  LK++               N+   K+  +  Q+     EI +K ++  +     
Sbjct: 808  DDENQSLKQTVNDLKLKIKQSGDEKNELTMKIKYMELQMSAPQKEIEEKLNQEVMKNQDL 867

Query: 1431 NDEFENVRQQLVE-YEKRIED---LTYEKESELAILRLKMHENANHYETMQKESEIE-RV 1485
             DE  ++  QL E  EKR      L   KE     +R      A + E   K++E+E +V
Sbjct: 868  QDEITSINTQLAEAVEKRKASEAALEEMKEQMDGKIRNSNDLEATYQECFNKKTELENKV 927

Query: 1486 KLIEELNVKITESV-SLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQ 1544
              +E     I +S+   + ++A+L   L              +  +++I T+N +  +L+
Sbjct: 928  ADLENQLEIIKDSIEEKDDKIADLQSQLSSNSNDAVANDKLGDAMQLKIDTINRQYLDLK 987

Query: 1545 N 1545
            +
Sbjct: 988  S 988



 Score =  103 bits (246), Expect = 5e-20
 Identities = 190/1063 (17%), Positives = 445/1063 (41%), Gaps = 90/1063 (8%)

Query: 536  KLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDS----- 590
            K KQ+  T    ++V +  + +++L  E   L  ++   E+   N Q  L + +      
Sbjct: 40   KAKQLDGTK---AEVGELEQTLIKLQNENAKLKNELQTKEDVIKNYQKELTEVEEKNKGV 96

Query: 591  -GRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQ 649
              R++E    +K  E+E   E +   I  L++   +L Q L  LQQ+    E+++  I++
Sbjct: 97   DDRILEEKEKRKSAELE--LENKKDDILELQAMVSNLKQNLAGLQQELKNKEEEI--ITE 152

Query: 650  LQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNK 709
                      + V+ +EQ + L +   ++ + ++  + +           E + EDI  +
Sbjct: 153  TDKSNKALAAQKVY-QEQKEKLESELADVKIKLDTTQQELVATQARADGNEKEIEDITQE 211

Query: 710  LQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIES 769
               +I++  + + +++ ++ E     L ++  +   +I+      A +++    +E+  +
Sbjct: 212  QNGWIRQAKEASKQIDSLNTE-----LEEVEKDLDDEIKRHTATKADLEKTKNDLESSNN 266

Query: 770  ELSKYKSRICRLE---ESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNR 826
            +++K K ++ + +   +    + D+     +  ++  S L++K + Y         LVN 
Sbjct: 267  QINKLKEQLEKTKAEKDENKNVADQEVVTRKAVERKVSDLEKKVEGYKTDYETSQNLVND 326

Query: 827  LAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRT 886
            L V +   R V K+  ++E   KE    N IL    Q+ Q    ++ + ++ L E+A +T
Sbjct: 327  LQVKL---RAVTKEKEDLE---KEYSSGNNILEVLQQSKQKGDEEIIKLHDDLAEQAKKT 380

Query: 887  DLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVL 946
                   T     ++ LE +   +  E   L ++  K+ + L  +   +++  ++D K L
Sbjct: 381  -------TDAMRDIKQLEYDKVALNGEITELNLELDKQ-KQLVTKLQQEVKQ-LQDDKEL 431

Query: 947  NEKYEKNIEYVTQ-LEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTE 1005
            NE+  ++  +  + L  Q+ + K  ++   M  E+L K  ++ +   + K   +  D  E
Sbjct: 432  NEQDIRDAGFENKKLTNQINDAKEAMDKELMKEEKL-KQEIQALKDTIAKNDEEH-DKLE 489

Query: 1006 QYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQ 1065
              IN   K    L+  ++ +    +     + + +      E+ L + + + + + E+ +
Sbjct: 490  SDINNNEKTIKQLQNANKVLTENLENCTRDKEAALRKKEQVETDLKEKSEEYDALNEKQR 549

Query: 1066 RVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDA 1125
             ++ QL+  ++ N  L   V      +K  K      +  +   +  I   T++      
Sbjct: 550  ELNSQLVTLQKENAGLNETVGTISPDLKNTKALLKQTQKELKDAKDKIEGLTLD------ 603

Query: 1126 NNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTEL 1185
             N D            + ++E E++ ++   LQ + AK+  +  +   ++  L+ L+   
Sbjct: 604  -NEDLKKKQKEILEGHVSMEELEDYEKQ---LQREVAKIKQKSDKEAEEL--LDALDASD 657

Query: 1186 TGHDVVNQEQINQLKSKLEQLNTENDNL--LSTVAELRSSI-SSAVDQRGFEIAELWKQH 1242
              ++ +N   INQ K  L++L  E++ +      AE R  I    V  +   IA+L K  
Sbjct: 658  KKNEKLNNI-INQYKENLDKLTQEHEEMEKAKNTAEKRVIIVQQDVKDKEETIAKLEKDK 716

Query: 1243 --LAQREADFQKT-------EHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQ-- 1291
              L  R  D +           ++ V ++A    Y++ +D +  + Q+  ++   +    
Sbjct: 717  NTLKDRITDLESRIDGLEGGNVDVSVVVNAATESYKKQIDDLNKTIQDAKDQEKDLRDEI 776

Query: 1292 ------VTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXX 1345
                  +  L+ +L+ KE+ +    +K   + ++ + L+  + D K+             
Sbjct: 777  KDLRLDIVDLKGELESKEQEVNKAGDKLVLIDDENQSLKQTVNDLKLKIKQSGDEKNELT 836

Query: 1346 XXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLEL 1405
                      +   K+++E+    + + N  L+               +   +EA + E+
Sbjct: 837  MKIKYMELQMSAPQKEIEEKLNQEVMK-NQDLQDEITSINTQLAEAVEKRKASEAALEEM 895

Query: 1406 THQLE--LKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILR 1463
              Q++  +++S   + T++       +  E EN    L    + I+D   EK+ ++A L+
Sbjct: 896  KEQMDGKIRNSNDLEATYQECFN---KKTELENKVADLENQLEIIKDSIEEKDDKIADLQ 952

Query: 1464 LKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQ 1523
             ++  N+N          +   KL + + +KI    ++N+Q  +L    ++  +    + 
Sbjct: 953  SQLSSNSN--------DAVANDKLGDAMQLKID---TINRQYLDLKSKYDQLKSDNLMVL 1001

Query: 1524 TALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQ 1566
            +  E+ E E+ ++ +E+T ++   R  +++I+K     + TKQ
Sbjct: 1002 SEKEDIEEELSSVKEEMTKMEGDYRKKAAEIEKLKHDVNFTKQ 1044



 Score = 93.5 bits (222), Expect = 4e-17
 Identities = 139/786 (17%), Positives = 330/786 (41%), Gaps = 43/786 (5%)

Query: 793  YSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQ 852
            Y   ++ D   + + E ++   +   +  +L N L    D  +  +K+L E+E +NK + 
Sbjct: 38   YHKAKQLDGTKAEVGELEQTLIKLQNENAKLKNELQTKEDVIKNYQKELTEVEEKNKGVD 97

Query: 853  KKNQILLEENQNLQISLSDMQQ---HYNALVE--KANRTDLAESESTKYQTQLRDLESNL 907
             +     E+ ++ ++ L + +       A+V   K N   L +    K +  + + + + 
Sbjct: 98   DRILEEKEKRKSAELELENKKDDILELQAMVSNLKQNLAGLQQELKNKEEEIITETDKSN 157

Query: 908  KRITHE--HQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLE---- 961
            K +  +  +Q    + + E+ D++I+ +T  +  +  +   +   EK IE +TQ +    
Sbjct: 158  KALAAQKVYQEQKEKLESELADVKIKLDTTQQELVATQARADGN-EKEIEDITQEQNGWI 216

Query: 962  AQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQT--QSPDYTEQYINEINKLNALLK 1019
             Q +E    I++LN  +EE+ K   + I +H   +    ++ +  E   N+INKL   L+
Sbjct: 217  RQAKEASKQIDSLNTELEEVEKDLDDEIKRHTATKADLEKTKNDLESSNNQINKLKEQLE 276

Query: 1020 ----QKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSK 1075
                +KDE     +Q++   + +    VSD E K+  + T  E  +  +  +  +L    
Sbjct: 277  KTKAEKDENKNVADQEVVTRK-AVERKVSDLEKKVEGYKTDYETSQNLVNDLQVKLRAVT 335

Query: 1076 QHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISS---TIEPMSDDAN-NVDXX 1131
            +  E+L+      ++ ++ L+++K   +  I K    +      T + M D      D  
Sbjct: 336  KEKEDLEKEYSSGNNILEVLQQSKQKGDEEIIKLHDDLAEQAKKTTDAMRDIKQLEYDKV 395

Query: 1132 XXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVV 1191
                      L++ ++++ + +   LQ++  +L  + +     I      N +LT     
Sbjct: 396  ALNGEITELNLELDKQKQLVTK---LQQEVKQLQDDKELNEQDIRDAGFENKKLTN---- 448

Query: 1192 NQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQ 1251
               QIN  K  +++   + + L   +  L+ +I+   ++      +  +  +   E   +
Sbjct: 449  ---QINDAKEAMDKELMKEEKLKQEIQALKDTIAKNDEEH-----DKLESDINNNEKTIK 500

Query: 1252 KTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQE 1311
            + ++  +V     E+       +++   Q ET+     E+  +L  K ++    L  LQ+
Sbjct: 501  QLQNANKVLTENLENCTRDKEAALRKKEQVETDLKEKSEEYDALNEKQRELNSQLVTLQK 560

Query: 1312 KYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNIN 1371
            + A +   +  +  ++++ K A                  L  +N+  K+ Q++ IL  +
Sbjct: 561  ENAGLNETVGTISPDLKNTK-ALLKQTQKELKDAKDKIEGLTLDNEDLKKKQKE-ILEGH 618

Query: 1372 EENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRN 1431
                +L+               + +    ++L+     + K+ ++    ++Y   L +  
Sbjct: 619  VSMEELEDYEKQLQREVAKIKQKSDKEAEELLDALDASDKKNEKLNNIINQYKENLDKLT 678

Query: 1432 DEFENVRQQLVEYEKRIEDLTYE-KESELAILRLKMHENANHYETMQKESEIERVKLIE- 1489
             E E + +     EKR+  +  + K+ E  I +L+  +N         ES I+ ++    
Sbjct: 679  QEHEEMEKAKNTAEKRVIIVQQDVKDKEETIAKLEKDKNTLKDRITDLESRIDGLEGGNV 738

Query: 1490 ELNVKITESV-SLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVR 1548
            +++V +  +  S  KQ+ +LNK +++   +  +++  +++  ++IV L  E+ + +  V 
Sbjct: 739  DVSVVVNAATESYKKQIDDLNKTIQDAKDQEKDLRDEIKDLRLDIVDLKGELESKEQEVN 798

Query: 1549 ASSSKI 1554
             +  K+
Sbjct: 799  KAGDKL 804



 Score = 58.0 bits (134), Expect = 2e-06
 Identities = 120/603 (19%), Positives = 255/603 (42%), Gaps = 64/603 (10%)

Query: 144  VTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXX 203
            +  L+ TI++  +    L+ ++K +   I+DL+ ++  K+Q +   NKA           
Sbjct: 755  IDDLNKTIQDAKDQEKDLRDEIKDLRLDIVDLKGELESKEQEV---NKAGDKLVLI---- 807

Query: 204  XXXXXXXXEDTKQQMTKMQENFIAMEAEWK-DEKQRLLKDIESKDVRISSLEEANKLLEA 262
                     D + Q  K   N + ++ +   DEK  L   I+  ++++S+ ++  ++ E 
Sbjct: 808  ---------DDENQSLKQTVNDLKLKIKQSGDEKNELTMKIKYMELQMSAPQK--EIEEK 856

Query: 263  ARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMT 322
               E+ +++  L  E+                  +++ E + EE  E +  G +  +N  
Sbjct: 857  LNQEV-MKNQDLQDEITSINTQLAEAVE-----KRKASEAALEEMKE-QMDGKIRNSNDL 909

Query: 323  ELTKKIELLEHLNCQIRQTNK--ELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTAS 380
            E T +    E  N +    NK  +LEN+L  +    +            +S  S    A+
Sbjct: 910  EATYQ----ECFNKKTELENKVADLENQLEIIKDSIEEKDDKIADLQSQLSSNSNDAVAN 965

Query: 381  KMKSPWSQLSSETLN-QDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXX 439
                   QL  +T+N Q  D K   +++    +++ S  +D+ ++   + E+ T      
Sbjct: 966  DKLGDAMQLKIDTINRQYLDLKSKYDQLKSDNLMVLSEKEDIEEELSSVKEEMTKMEG-- 1023

Query: 440  XXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVK 499
                  D      ++E  +H    +    G +  D+ ++ +  +QL+++ +D ++D +  
Sbjct: 1024 ------DYRKKAAEIEKLKHDVNFTKQVTGDDANDLEKLQEDYDQLQEDYDDLMEDSDA- 1076

Query: 500  DLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVR 559
             L  K +  E+++T+L DE++ +     K+K+  K   KQ  +  D+     +++ + VR
Sbjct: 1077 -LTAKNQQLEKRVTELTDEVEISQD---KIKALEKQLRKQNNELEDHADDAENADDDYVR 1132

Query: 560  LTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLL 619
            +  +    + K+ +  +E  N    + +         D  KK I  +++  T L+  +  
Sbjct: 1133 MKAD----NDKIRKERDEYRNKITEMEE-------NMDQLKKTITEQDIKITELRGGNGE 1181

Query: 620  ESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELA 679
            E+ K    Q   I ++   E E+ LA   Q ++     + ++  L E+++ L    ++  
Sbjct: 1182 EALKIK-AQIKQIEEENDKEKEELLAKAQQFKTKMNKFKKQAQELAEKVEDLEGQLEKAK 1240

Query: 680  LVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDK---LEKMSAEKISELL 736
                        L   IKDL+++ ED+  KL +  +++  L  K   LE  S +K  E +
Sbjct: 1241 --GSAAAAGASDLKSKIKDLQDEIEDVNQKLSSEKEKSSRLQRKVTSLESDSQDK-DEQI 1297

Query: 737  AKI 739
            AK+
Sbjct: 1298 AKL 1300


>UniRef50_P25386 Cluster: Intracellular protein transport protein
            USO1; n=3; Saccharomyces cerevisiae|Rep: Intracellular
            protein transport protein USO1 - Saccharomyces cerevisiae
            (Baker's yeast)
          Length = 1790

 Score =  139 bits (336), Expect = 7e-31
 Identities = 214/1024 (20%), Positives = 446/1024 (43%), Gaps = 88/1024 (8%)

Query: 159  SVLQVKMKIMETTILDLQEKINEKDQ---IIEAKNKATTXXXXXXXXXXXXXXXXXEDTK 215
            S L+    I+ET + ++++ ++E  Q   ++E K+K                    ED+ 
Sbjct: 786  SSLKENFSILETELKNVRDSLDEMTQLRDVLETKDKENQTALLEYKSTIHKQ----EDSI 841

Query: 216  QQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLA 275
            + + K  E  ++ + + +D   ++ KD+ +    + ++EE  K L+  + + ++ H K  
Sbjct: 842  KTLEKGLETILSQKKKAEDGINKMGKDLFALSREMQAVEENCKNLQKEKDKSNVNHQKET 901

Query: 276  QEL-EQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHL 334
            + L E               L +  I+  C   ++ +E  S E   + E   + +  ++L
Sbjct: 902  KSLKEDIAAKITEIKAINENLEEMKIQ--CNNLSKEKEHISKE---LVEYKSRFQSHDNL 956

Query: 335  NCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETL 394
              ++ +  K L N    M  E++++    ++     S+       S +++    +S E  
Sbjct: 957  VAKLTEKLKSLANNYKDMQAENESLIKAVEE-----SKNESSIQLSNLQNKIDSMSQEKE 1011

Query: 395  NQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQL 454
            N   ++   +  I +L+  I  L +    KE +IS+ D+              L  +L+ 
Sbjct: 1012 NFQIERGSIEKNIEQLKKTISDLEQ---TKEEIISKSDSSKDEYESQI---SLLKEKLET 1065

Query: 455  EHQQHMEGPSLIHVGTNT-EDVNEIAKVQEQLKQELNDE-------IKDV--NVKDLIEK 504
                + E  + I   T T E++       + LK EL  +       +K+V  N + L E+
Sbjct: 1066 ATTANDENVNKISELTKTREELEAELAAYKNLKNELETKLETSEKALKEVKENEEHLKEE 1125

Query: 505  LKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNF-SKVSDSNKEIVRLTEE 563
                E++ T+   ++++   N+  ++  H+    Q++K  +   +K    N+EI +L +E
Sbjct: 1126 KIQLEKEATETKQQLNSLRANLESLEKEHEDLAAQLKKYEEQIANKERQYNEEISQLNDE 1185

Query: 564  LHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLK------AIS 617
            +    Q+   ++++   L+  +    S    +S++ K  I+  NL    LK        S
Sbjct: 1186 ITSTQQENESIKKKNDELEGEVKAMKSTSEEQSNLKKSEIDALNLQIKELKKKNETNEAS 1245

Query: 618  LLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIK-SVHLEEQIDALSASKK 676
            LLES K  +  E   +++  DE   K  ++S+L+     SE K S +LE Q ++    K+
Sbjct: 1246 LLESIK-SVESETVKIKELQDECNFKEKEVSELEDKLKASEDKNSKYLELQKES-EKIKE 1303

Query: 677  ELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAE-----K 731
            EL      LK+  E++    K  E  + ++    +   +E  +  ++LEK+  E     +
Sbjct: 1304 ELDAKTTELKIQLEKITNLSKAKEKSESELSRLKKTSSEERKNAEEQLEKLKNEIQIKNQ 1363

Query: 732  ISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLE-ESIAVMED 790
              E   K+ +E  S I  ++       E +L     E+EL   +    R E E +++  D
Sbjct: 1364 AFEKERKLLNEGSSTITQEYSEKINTLEDELIRLQNENELKAKEIDNTRSELEKVSLSND 1423

Query: 791  RRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVE--KQLLEIEHEN 848
                LE K + + S LQ++  +Y +   + DE +  L++  D+ R +E  K+ L    E+
Sbjct: 1424 E--LLEEKQNTIKS-LQDEILSYKDKITRNDEKL--LSIERDNKRDLESLKEQLRAAQES 1478

Query: 849  K-ELQKKNQILLEENQNLQISL---SDMQQHYNALVEKANRTDLAESEST------KYQT 898
            K ++++  + L EE+   +  L    +M +   + +E +N T+L  S  T      K + 
Sbjct: 1479 KAKVEEGLKKLEEESSKEKAELEKSKEMMKKLESTIE-SNETELKSSMETIRKSDEKLEQ 1537

Query: 899  QLRDLESNLKRITHEHQTLIV---QKKKEIEDL------EIEFNTQIESAIRDKKVLNEK 949
              +  E ++K + HE   LI    + +K+IE+L      E +  +++E+  ++     EK
Sbjct: 1538 SKKSAEEDIKNLQHEKSDLISRINESEKDIEELKSKLRIEAKSGSELETVKQELNNAQEK 1597

Query: 950  YEKNIEYVTQLEAQLQEYKNNIEN------LNMNVEELNKMNLELIDKHVQKQQTQSPDY 1003
               N E  T L+++L++ +  +++       N   +EL    L+ +++ +   Q ++   
Sbjct: 1598 IRINAEENTVLKSKLEDIERELKDKQAEIKSNQEEKELLTSRLKELEQELDSTQQKAQKS 1657

Query: 1004 TEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEE 1063
             E+   E+ K      Q DE+ + L  K N+      +   D ++   + TT  ++  +E
Sbjct: 1658 EEERRAEVRKFQVEKSQLDEKAMLLETKYNDLVNKEQAWKRDEDT--VKKTT--DSQRQE 1713

Query: 1064 MQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSD 1123
            +++++K+L + K  N +L+    E   +I +L       +    K    +    +E  SD
Sbjct: 1714 IEKLAKELDNLKAENSKLK-EANEDRSEIDDLMLLVTDLDEKNAKYRSKLKDLGVEISSD 1772

Query: 1124 DANN 1127
            + ++
Sbjct: 1773 EEDD 1776



 Score =  136 bits (330), Expect = 4e-30
 Identities = 180/916 (19%), Positives = 413/916 (45%), Gaps = 81/916 (8%)

Query: 486  KQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTID 545
            KQE + +  +  ++ ++ + K AE+ I ++  ++ A ++ M  V+ N K   K+  K+  
Sbjct: 836  KQEDSIKTLEKGLETILSQKKKAEDGINKMGKDLFALSREMQAVEENCKNLQKEKDKSNV 895

Query: 546  NFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEM 605
            N  K + S KE          ++ K+ E++    NL+   +  ++    +  + K+++E 
Sbjct: 896  NHQKETKSLKE---------DIAAKITEIKAINENLEEMKIQCNNLSKEKEHISKELVEY 946

Query: 606  ENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLE 665
            ++  ++    ++ L  +   L      +Q + + +      I  ++  +  S I+  +L+
Sbjct: 947  KSRFQSHDNLVAKLTEKLKSLANNYKDMQAENESL------IKAVEESKNESSIQLSNLQ 1000

Query: 666  EQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQN----YIQENMDLT 721
             +ID++S  K+   +   +++ + EQL  TI DLE  KE+I++K  +    Y  +   L 
Sbjct: 1001 NKIDSMSQEKENFQIERGSIEKNIEQLKKTISDLEQTKEEIISKSDSSKDEYESQISLLK 1060

Query: 722  DKLEKM------SAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYK 775
            +KLE        +  KISE L K   E ++++     +  +++ +   +E  E  L + K
Sbjct: 1061 EKLETATTANDENVNKISE-LTKTREELEAELAAYKNLKNELETK---LETSEKALKEVK 1116

Query: 776  SRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQ----EDELVNRLAVLM 831
                 L+E    +E      +++ + L + L+  +K + +   Q    E+++ N+     
Sbjct: 1117 ENEEHLKEEKIQLEKEATETKQQLNSLRANLESLEKEHEDLAAQLKKYEEQIANKERQYN 1176

Query: 832  DHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAES 891
            +    +  ++   + EN+ ++KKN  L  E + ++ S S+ Q +       A    + E 
Sbjct: 1177 EEISQLNDEITSTQQENESIKKKNDELEGEVKAMK-STSEEQSNLKKSEIDALNLQIKEL 1235

Query: 892  ESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKY- 950
            +  K +T    L  ++K +  E +T+ +++ ++  + + +  +++E  ++  +  N KY 
Sbjct: 1236 KK-KNETNEASLLESIKSV--ESETVKIKELQDECNFKEKEVSELEDKLKASEDKNSKYL 1292

Query: 951  --EKNIEYV-TQLEAQLQEYKNNIENL-NMN-VEELNKMNLELIDKHVQKQQTQSPDYTE 1005
              +K  E +  +L+A+  E K  +E + N++  +E ++  L  + K   +++  + +  E
Sbjct: 1293 ELQKESEKIKEELDAKTTELKIQLEKITNLSKAKEKSESELSRLKKTSSEERKNAEEQLE 1352

Query: 1006 QYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQ 1065
            +  NEI   N    +K+ ++  LN+  +     Y   ++  E +L +   + E   +E+ 
Sbjct: 1353 KLKNEIQIKNQAF-EKERKL--LNEGSSTITQEYSEKINTLEDELIRLQNENELKAKEID 1409

Query: 1066 RVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDA 1125
                +L      N+E   L+ E+ + IK L++  L+++  I + +  ++S  IE   D+ 
Sbjct: 1410 NTRSELEKVSLSNDE---LLEEKQNTIKSLQDEILSYKDKITRNDEKLLS--IE--RDNK 1462

Query: 1126 NNVDXXXXXXXXXXXXLKVQEEEEFIQE-RSVLQEQSAKLNTELQECYTKIIQLETLNTE 1184
             +++               QE +  ++E    L+E+S+K   EL++    + +LE+    
Sbjct: 1463 RDLESLKEQLRA------AQESKAKVEEGLKKLEEESSKEKAELEKSKEMMKKLES---- 1512

Query: 1185 LTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLA 1244
                 + + E   +LKS +E +   ++ L  +       I +   ++   I+      + 
Sbjct: 1513 ----TIESNE--TELKSSMETIRKSDEKLEQSKKSAEEDIKNLQHEKSDLIS-----RIN 1561

Query: 1245 QREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKI-VTMEQVTSLQNKLQDKE 1303
            + E D ++ + +LR+     E+K    L++V+        KI +  E+ T L++KL+D E
Sbjct: 1562 ESEKDIEELKSKLRI-----EAKSGSELETVKQELNNAQEKIRINAEENTVLKSKLEDIE 1616

Query: 1304 EHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQ 1363
              L++ Q +      + E+L S +++ +                   ++R       Q+ 
Sbjct: 1617 RELKDKQAEIKSNQEEKELLTSRLKELEQELDSTQQKAQKSEEERRAEVRKFQVEKSQLD 1676

Query: 1364 EQSILNINEENAQLKK 1379
            E+++L   + N  + K
Sbjct: 1677 EKAMLLETKYNDLVNK 1692



 Score =  113 bits (272), Expect = 4e-23
 Identities = 176/829 (21%), Positives = 362/829 (43%), Gaps = 88/829 (10%)

Query: 833  HDRVVEKQLLEIEHENKELQKKNQIL------LEEN--------QNLQISLSDMQQHYNA 878
            H+ + EK L+ + +E+KEL +K QIL      L+EN        +N++ SL +M Q  + 
Sbjct: 757  HENLTEK-LIALTNEHKELDEKYQILNSSHSSLKENFSILETELKNVRDSLDEMTQLRDV 815

Query: 879  L--VEKANRTDLAESEST--KYQTQLRDLESNLKRITHEHQTL---IVQKKKEIEDLEIE 931
            L   +K N+T L E +ST  K +  ++ LE  L+ I  + +     I +  K++  L  E
Sbjct: 816  LETKDKENQTALLEYKSTIHKQEDSIKTLEKGLETILSQKKKAEDGINKMGKDLFALSRE 875

Query: 932  FNTQIESAIRDKKVLNEKYEKNIEY---VTQLEAQLQEYKNNIENLNMNVEELNKM--NL 986
                 E+    K +  EK + N+ +      L+  +      I+ +N N+EE+     NL
Sbjct: 876  MQAVEENC---KNLQKEKDKSNVNHQKETKSLKEDIAAKITEIKAINENLEEMKIQCNNL 932

Query: 987  ELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQ----------KDEEII-ALNQKINNA 1035
                +H+ K+  +     + + N + KL   LK           ++E +I A+ +  N +
Sbjct: 933  SKEKEHISKELVEYKSRFQSHDNLVAKLTEKLKSLANNYKDMQAENESLIKAVEESKNES 992

Query: 1036 QVSYMSMVSDYES---KLAQFTTKLENMEEEMQRVSKQLLDSKQHNEEL----QILVREQ 1088
             +   ++ +  +S   +   F  +  ++E+ ++++ K + D +Q  EE+         E 
Sbjct: 993  SIQLSNLQNKIDSMSQEKENFQIERGSIEKNIEQLKKTISDLEQTKEEIISKSDSSKDEY 1052

Query: 1089 DDQIKELKETKLTFEMNIPKTEGMI--ISSTIEPMSDD----ANNVDXXXXXXXXXXXXL 1142
            + QI  LKE   T      +    I  ++ T E +  +     N  +            L
Sbjct: 1053 ESQISLLKEKLETATTANDENVNKISELTKTREELEAELAAYKNLKNELETKLETSEKAL 1112

Query: 1143 K-VQEEEEFIQERSV-LQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQI-NQL 1199
            K V+E EE ++E  + L++++ +   +L      +  LE  + +L       +EQI N+ 
Sbjct: 1113 KEVKENEEHLKEEKIQLEKEATETKQQLNSLRANLESLEKEHEDLAAQLKKYEEQIANKE 1172

Query: 1200 KSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHE-LR 1258
            +   E+++  ND + ST  E   SI    D+   E+  +  +  ++ +++ +K+E + L 
Sbjct: 1173 RQYNEEISQLNDEITSTQQE-NESIKKKNDELEGEVKAM--KSTSEEQSNLKKSEIDALN 1229

Query: 1259 VQLSAFESKYE----QLLDSVQSSTQEETNKIVTMEQVTSLQNK----LQDKEEHLRNLQ 1310
            +Q+   + K E     LL+S++ S + ET KI  ++   + + K    L+DK +   +  
Sbjct: 1230 LQIKELKKKNETNEASLLESIK-SVESETVKIKELQDECNFKEKEVSELEDKLKASEDKN 1288

Query: 1311 EKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNI 1370
             KY ++  + E ++ E+ D K                      +E    K+   +   N 
Sbjct: 1289 SKYLELQKESEKIKEEL-DAKTTELKIQLEKITNLSKAKEKSESELSRLKKTSSEERKNA 1347

Query: 1371 NEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVL-ELTHQLELKDSEIYQKTHEYTITLTQ 1429
             E+  +LK                +N+  + +  E + ++   + E+ +  +E  +    
Sbjct: 1348 EEQLEKLKNEIQIKNQAFEKERKLLNEGSSTITQEYSEKINTLEDELIRLQNENEL---- 1403

Query: 1430 RNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIE 1489
            +  E +N R +L +     ++L  EK++ +  L+    E  ++ + + +    E++  IE
Sbjct: 1404 KAKEIDNTRSELEKVSLSNDELLEEKQNTIKSLQ---DEILSYKDKITRND--EKLLSIE 1458

Query: 1490 ELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIE-----IVTLNDEITNLQ 1544
              N +  ES+    + A+ +KA  EE  K  E +++ E  E+E     +  L   I + +
Sbjct: 1459 RDNKRDLESLKEQLRAAQESKAKVEEGLKKLEEESSKEKAELEKSKEMMKKLESTIESNE 1518

Query: 1545 NMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNK--ELLDAVPRAELDL 1591
              +++S   I+K       +K+  +E + N  ++  +L+  +  +E D+
Sbjct: 1519 TELKSSMETIRKSDEKLEQSKKSAEEDIKNLQHEKSDLISRINESEKDI 1567



 Score =  111 bits (267), Expect = 2e-22
 Identities = 197/1087 (18%), Positives = 463/1087 (42%), Gaps = 69/1087 (6%)

Query: 212  EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271
            E  ++Q TK++    +++ E +   + L + + +       L+E  ++L ++   +    
Sbjct: 733  EKLQRQCTKLKGEITSLQTETESTHENLTEKLIALTNEHKELDEKYQILNSSHSSLKENF 792

Query: 272  SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSL--EIANMTELTKKIE 329
            S L  EL+               L  +  E    +   +E K ++  +  ++  L K +E
Sbjct: 793  SILETELKNVRDSLDEMTQLRDVLETKDKE---NQTALLEYKSTIHKQEDSIKTLEKGLE 849

Query: 330  LLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQL 389
             +     +      ++   L  +  E +AV   + K       KS  N   + KS    +
Sbjct: 850  TILSQKKKAEDGINKMGKDLFALSREMQAVEE-NCKNLQKEKDKSNVNHQKETKSLKEDI 908

Query: 390  SS-----ETLNQDTDK-KINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXX 443
            ++     + +N++ ++ KI  N ++K +   + ++K+LV+ +      D           
Sbjct: 909  AAKITEIKAINENLEEMKIQCNNLSKEK---EHISKELVEYKSRFQSHDNLVAKLTEKLK 965

Query: 444  GKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIE 503
                    +Q E++  ++        ++ +  N   K+    +++ N +I+  +++  IE
Sbjct: 966  SLANNYKDMQAENESLIKAVEESKNESSIQLSNLQNKIDSMSQEKENFQIERGSIEKNIE 1025

Query: 504  KLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSN-KEIVRLTE 562
            +LK     + Q  +EI + + +    K  ++ ++  +++ ++  +  +D N  +I  LT+
Sbjct: 1026 QLKKTISDLEQTKEEIISKSDSS---KDEYESQISLLKEKLETATTANDENVNKISELTK 1082

Query: 563  ELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQ 622
                L  ++A  +  K  L+  L         E  + +     E+L E +++    LE +
Sbjct: 1083 TREELEAELAAYKNLKNELETKL------ETSEKALKEVKENEEHLKEEKIQ----LEKE 1132

Query: 623  KFDLVQELHILQQKYDEVEDKLADI-SQLQSDQVCSEIKSVHLEEQIDALSASKKELALV 681
              +  Q+L+ L+   + +E +  D+ +QL+  +     K     E+I  L+         
Sbjct: 1133 ATETKQQLNSLRANLESLEKEHEDLAAQLKKYEEQIANKERQYNEEISQLNDEITSTQQE 1192

Query: 682  IENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQE-NMDLTDKLEKMSAEKISELLAKIN 740
             E++K   ++L G +K +++  E+  N  ++ I   N+ + + L+K +    + LL  I 
Sbjct: 1193 NESIKKKNDELEGEVKAMKSTSEEQSNLKKSEIDALNLQIKE-LKKKNETNEASLLESIK 1251

Query: 741  HEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKAD 800
              E   ++ +  +  +   ++  +  +E +L   + +  +  E     E  +  L+ K  
Sbjct: 1252 SVESETVKIK-ELQDECNFKEKEVSELEDKLKASEDKNSKYLELQKESEKIKEELDAKTT 1310

Query: 801  QLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLE 860
            +L   L++           E EL        +  +  E+QL ++++   E+Q KNQ   +
Sbjct: 1311 ELKIQLEKITNLSKAKEKSESELSRLKKTSSEERKNAEEQLEKLKN---EIQIKNQAFEK 1367

Query: 861  ENQNLQISLSDMQQHYNALVEK-ANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIV 919
            E + L    S + Q Y+  +    +     ++E+     ++ +  S L++++  +  L+ 
Sbjct: 1368 ERKLLNEGSSTITQEYSEKINTLEDELIRLQNENELKAKEIDNTRSELEKVSLSNDELLE 1427

Query: 920  QKKKEIEDLEIEFNTQIESAIR-DKKVLN--EKYEKNIEYVTQLEAQLQEYKNNI-ENLN 975
            +K+  I+ L+ E  +  +   R D+K+L+     ++++E + +     QE K  + E L 
Sbjct: 1428 EKQNTIKSLQDEILSYKDKITRNDEKLLSIERDNKRDLESLKEQLRAAQESKAKVEEGLK 1487

Query: 976  MNVEELNKMNLEL-IDKHVQK--QQTQSPDYTE--QYINEINKLNALLKQKDEEIIALNQ 1030
               EE +K   EL   K + K  + T   + TE    +  I K +  L+Q  +      +
Sbjct: 1488 KLEEESSKEKAELEKSKEMMKKLESTIESNETELKSSMETIRKSDEKLEQSKKSAEEDIK 1547

Query: 1031 KINNAQVSYMSMVSDYESKLAQFTTKLE---NMEEEMQRVSKQLLDSKQ----HNEELQI 1083
             + + +   +S +++ E  + +  +KL        E++ V ++L ++++    + EE  +
Sbjct: 1548 NLQHEKSDLISRINESEKDIEELKSKLRIEAKSGSELETVKQELNNAQEKIRINAEENTV 1607

Query: 1084 LVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLK 1143
            L  + +D  +ELK+ +   + N  + E  +++S ++ +  + ++               +
Sbjct: 1608 LKSKLEDIERELKDKQAEIKSN--QEEKELLTSRLKELEQELDSTQQKAQKSEEE----R 1661

Query: 1144 VQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKL 1203
              E  +F  E+S L E++  L T+    Y  ++  E         D V +   +Q + ++
Sbjct: 1662 RAEVRKFQVEKSQLDEKAMLLETK----YNDLVNKE--QAWKRDEDTVKKTTDSQ-RQEI 1714

Query: 1204 EQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSA 1263
            E+L  E DNL +  ++L+ +     D+   +   L    L ++ A ++    +L V++S+
Sbjct: 1715 EKLAKELDNLKAENSKLKEANE---DRSEIDDLMLLVTDLDEKNAKYRSKLKDLGVEISS 1771

Query: 1264 FESKYEQ 1270
             E   E+
Sbjct: 1772 DEEDDEE 1778



 Score = 91.9 bits (218), Expect = 1e-16
 Identities = 129/617 (20%), Positives = 265/617 (42%), Gaps = 59/617 (9%)

Query: 979  EELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVS 1038
            E +NK++ E ++K +Q+Q T+          E    +  L +K   +IAL  +       
Sbjct: 722  EPINKISFEEVEK-LQRQCTKLKGEITSLQTETESTHENLTEK---LIALTNEHKELDEK 777

Query: 1039 YMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKET 1098
            Y  + S + S    F+     +E E++ V   L +  Q  + L+   +E    + E K T
Sbjct: 778  YQILNSSHSSLKENFSI----LETELKNVRDSLDEMTQLRDVLETKDKENQTALLEYKST 833

Query: 1099 KLTFEMNIPKTE-GMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVL 1157
                E +I   E G+    + +  ++D  N               ++Q  EE  +    L
Sbjct: 834  IHKQEDSIKTLEKGLETILSQKKKAEDGIN----KMGKDLFALSREMQAVEENCKN---L 886

Query: 1158 QEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTV 1217
            Q++  K N   Q+  TK ++ E +  ++T    +N E + ++K +   L+ E +++   +
Sbjct: 887  QKEKDKSNVNHQK-ETKSLK-EDIAAKITEIKAIN-ENLEEMKIQCNNLSKEKEHISKEL 943

Query: 1218 AELRSSISS------AVDQRGFEIAELWKQHLAQREA---DFQKTEHELRVQLSAFESKY 1268
             E +S   S       + ++   +A  +K   A+ E+     +++++E  +QLS  ++K 
Sbjct: 944  VEYKSRFQSHDNLVAKLTEKLKSLANNYKDMQAENESLIKAVEESKNESSIQLSNLQNKI 1003

Query: 1269 EQLLDSVQSSTQEETNKIVTMEQVTSLQNKL-QDKEEHLRNLQEKYADVINQIEILRSEI 1327
            + +    ++   E  +    +EQ+    + L Q KEE +        +  +QI +L+ ++
Sbjct: 1004 DSMSQEKENFQIERGSIEKNIEQLKKTISDLEQTKEEIISKSDSSKDEYESQISLLKEKL 1063

Query: 1328 EDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXX 1387
            E    A                 +L  E  +YK ++ +    +      LK+        
Sbjct: 1064 ETATTA-NDENVNKISELTKTREELEAELAAYKNLKNELETKLETSEKALKE-------- 1114

Query: 1388 XXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKR 1447
                   V + E  + E   QLE + +E  Q+ +     L     E E++  QL +YE++
Sbjct: 1115 -------VKENEEHLKEEKIQLEKEATETKQQLNSLRANLESLEKEHEDLAAQLKKYEEQ 1167

Query: 1448 IEDLTYEKESELAILRLKMHENANHYETMQK-----ESEIERVKLI--EELNVKITESVS 1500
            I +   +   E++ L  ++       E+++K     E E++ +K    E+ N+K +E  +
Sbjct: 1168 IANKERQYNEEISQLNDEITSTQQENESIKKKNDELEGEVKAMKSTSEEQSNLKKSEIDA 1227

Query: 1501 LNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLND-------EITNLQNMVRASSSK 1553
            LN Q+ EL K  E   A   E   ++E++ ++I  L D       E++ L++ ++AS  K
Sbjct: 1228 LNLQIKELKKKNETNEASLLESIKSVESETVKIKELQDECNFKEKEVSELEDKLKASEDK 1287

Query: 1554 IQKHVSFASDTKQGRDE 1570
              K++    ++++ ++E
Sbjct: 1288 NSKYLELQKESEKIKEE 1304



 Score = 85.4 bits (202), Expect = 1e-14
 Identities = 172/790 (21%), Positives = 348/790 (44%), Gaps = 111/790 (14%)

Query: 813  YSEYTIQE-DELVNRLAVLMDHDRVVEKQLLEIEHENKE-LQKKNQILLEENQNLQISLS 870
            +S Y IQ  +E + R+   + HD   E+ + +I  E  E LQ++   L  E  +LQ    
Sbjct: 696  FSTYFIQLFNENIYRIRTALSHDPD-EEPINKISFEEVEKLQRQCTKLKGEITSLQTETE 754

Query: 871  DMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEI 930
                H N   +    T+  +    KYQ  L    S+LK    E+ +++  + K + D  +
Sbjct: 755  ST--HENLTEKLIALTNEHKELDEKYQI-LNSSHSSLK----ENFSILETELKNVRD-SL 806

Query: 931  EFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELID 990
            +  TQ+    RD  VL  K ++N   + + ++ + + +++I+ L   +E +     +  D
Sbjct: 807  DEMTQL----RD--VLETKDKENQTALLEYKSTIHKQEDSIKTLEKGLETILSQKKKAED 860

Query: 991  KHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYES-- 1048
               +  +       E    E N  N L K+KD+  +   ++  + +    + +++ ++  
Sbjct: 861  GINKMGKDLFALSREMQAVEENCKN-LQKEKDKSNVNHQKETKSLKEDIAAKITEIKAIN 919

Query: 1049 -KLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKEL----KETKLTFE 1103
              L +   +  N+ +E + +SK+L++ K   +    LV +  +++K L    K+ +   E
Sbjct: 920  ENLEEMKIQCNNLSKEKEHISKELVEYKSRFQSHDNLVAKLTEKLKSLANNYKDMQAENE 979

Query: 1104 MNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQ---EQ 1160
              I   E     S+I+ +S+  N +D               QE+E F  ER  ++   EQ
Sbjct: 980  SLIKAVEESKNESSIQ-LSNLQNKIDSMS------------QEKENFQIERGSIEKNIEQ 1026

Query: 1161 SAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAEL 1220
              K  ++L++   +II     + +        + QI+ LK KLE   T ND  ++ ++EL
Sbjct: 1027 LKKTISDLEQTKEEIISKSDSSKD------EYESQISLLKEKLETATTANDENVNKISEL 1080

Query: 1221 RSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQ 1280
              +                ++ L    A ++  ++EL  +L   E   +++ ++ +   +
Sbjct: 1081 TKT----------------REELEAELAAYKNLKNELETKLETSEKALKEVKENEEHLKE 1124

Query: 1281 EETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXX 1340
            E   KI   ++ T  + +L     +L +L++++ D+  Q++    +I +++         
Sbjct: 1125 E---KIQLEKEATETKQQLNSLRANLESLEKEHEDLAAQLKKYEEQIANKE--------- 1172

Query: 1341 XXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVND-AE 1399
                        R  N+   Q+ ++ I +  +EN  +KK +               + + 
Sbjct: 1173 ------------RQYNEEISQLNDE-ITSTQQENESIKKKNDELEGEVKAMKSTSEEQSN 1219

Query: 1400 AKVLELTH-QLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESE 1458
             K  E+    L++K+ +   +T+E ++  + ++ E E V+       K ++D    KE E
Sbjct: 1220 LKKSEIDALNLQIKELKKKNETNEASLLESIKSVESETVKI------KELQDECNFKEKE 1273

Query: 1459 LAIL--RLKMHENANH-YETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEE 1515
            ++ L  +LK  E+ N  Y  +QKESE    K+ EEL+ K TE     +++  L+KA E+ 
Sbjct: 1274 VSELEDKLKASEDKNSKYLELQKESE----KIKEELDAKTTELKIQLEKITNLSKAKEKS 1329

Query: 1516 VAKTNEM-QTALE---NQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQ 1571
             ++ + + +T+ E   N E ++  L +EI  ++N       K+    S  S   Q   E+
Sbjct: 1330 ESELSRLKKTSSEERKNAEEQLEKLKNEI-QIKNQAFEKERKLLNEGS--STITQEYSEK 1386

Query: 1572 LDNTMNKELL 1581
            + NT+  EL+
Sbjct: 1387 I-NTLEDELI 1395


>UniRef50_A2ESM9 Cluster: Putative uncharacterized protein; n=1;
            Trichomonas vaginalis G3|Rep: Putative uncharacterized
            protein - Trichomonas vaginalis G3
          Length = 1105

 Score =  138 bits (335), Expect = 9e-31
 Identities = 187/976 (19%), Positives = 417/976 (42%), Gaps = 64/976 (6%)

Query: 381  KMKSPWSQLSSETLNQDTDKKI-NKNEIAKLEMVIQSLNKDL---VDKEYVISEKDTXXX 436
            ++KS   + S   +N  +   I  K+EI++ +  IQ  N      +  +  +S+ D    
Sbjct: 134  QLKSLQDENSQLRVNSISSTSILQKSEISRPQKTIQDFNSPTFLHIFAQVDVSDLDRKLK 193

Query: 437  XXXXXXXGKDTLIAQLQLEHQQHMEG--PSLIHVGTNTEDVNEIAKVQEQLKQEL--NDE 492
                       L+  LQ   +Q+       +I + T  +D   +  V+ +LKQEL  N +
Sbjct: 194  ALQTDSKTASKLVNSLQKSFKQYTTQMKSKMIEIATQCKD--RVDSVERRLKQELERNSQ 251

Query: 493  IKDVNVKDLIEKLKSAEEQI-TQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVS 551
            +K     + I  L +  E+  TQL DE++ + +   ++K +    L   +  I    +  
Sbjct: 252  LKHRYDDETIPSLMANHEETETQLRDELNQSMRESDRIKRD----LLDRENAIKTLKR-- 305

Query: 552  DSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAET 611
               +++  + E L + + K   +EEE   L+      ++  +  S V  K  E  N A+ 
Sbjct: 306  -QQRQLFSVCESLKNQNTK---MEEELSQLRSETA-MNASALSTSSV--KYDEAMNEAKR 358

Query: 612  RLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDAL 671
              + I+ L+        ++    Q+ D  E +LA + + + +          +++ I  L
Sbjct: 359  ANEEINQLQGVLNIAKNKVKKATQRADAAEKELAQLKRNEEE----------MQQSIADL 408

Query: 672  SASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLE--KMSA 729
            + S  E    +++L+   +QL            ++ ++L     EN  +  KL   ++ A
Sbjct: 409  TTSNGEKESKLKDLREANKQLKNKCIQQNEQINELQHELDTIKAENESMQKKLNAAQIEA 468

Query: 730  EKISELLAKINHEEQSKIQTQ---FGIDAKIQERDLYIEN-IESELSKYKSRICRLEESI 785
            + + + L     +E+S ++ +    G  AK  E+   I N ++ +  K + +I  LE+ +
Sbjct: 469  KNLQQSLTNA-FDEKSVLEEKADSLGTTAKEYEKLKQILNDLKQKKEKAEGQITDLEQKL 527

Query: 786  AVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIE 845
               E+ + +L++   + G+ +Q +Q    +   + DE+ N +   ++ ++ +E QL  ++
Sbjct: 528  EKSEEEKTALDKTVKEQGNQIQREQAQIKQLIGENDEMQNLIEEKINDNKKLETQLKNLQ 587

Query: 846  HENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLES 905
             +  +L  +   L      LQ SL D  Q  + L       D    +    Q ++    +
Sbjct: 588  QQLDQLSNEKAELQSNTTILQASLDDKNQKISQLKSDIQEKDAKAFDVQSEQEEMNAKLA 647

Query: 906  NLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQ 965
            NL++I  +H+  I   KK++ D     +  I     +K  LNE+  +  + +  L+ + Q
Sbjct: 648  NLEKINDKHKKKIEDLKKQLGD----SSATIVKVENEKNDLNEELGRLKKALESLKQESQ 703

Query: 966  EYKNNIENLNMNVEELNKMNLELIDK--HVQKQQTQSPDYTEQYINEINKLNALLKQKDE 1023
             Y++  + L   +EE  ++  ++ DK  ++ K   Q  ++T +     ++L  +  Q D+
Sbjct: 704  GYQDANKKL---IEENEQLENQIKDKDGNIDKLSRQIQNHTNRISENESQLGEVQSQLDD 760

Query: 1024 EIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQI 1083
              + ++ +    Q      ++   ++      +++ +E + Q ++++L ++K   +ELQ 
Sbjct: 761  AAMTVHSQDQKIQ-QLQRQLAQLTTQKQVSDDRIKELERQNQGIARKLANAK---DELQT 816

Query: 1084 LVREQDDQIKELKETKLTFEMNIPKTEGMII----SSTIEPMSDDANNVDXXXXXXXXXX 1139
             +    +   +++  +   E++I   EG  +      TI+ +++  N             
Sbjct: 817  ALHNNAENEDKIQSQQR--ELDILHKEGESLQKRNQQTIDDLTNQLNKTKEELRQTEQQL 874

Query: 1140 XXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQL 1199
              L+  +E    + ++ + +  ++L+    +      QLE    +       +  QI   
Sbjct: 875  RELQKMKENNDDKMQTAITDLGSELDRTKAKLQATSRQLEQQTKQAQQDKEASDSQIENQ 934

Query: 1200 KSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQ-HLAQREAD-FQKTEHEL 1257
            K ++E+LN   ++L + + +   S+ ++ +    ++ +L    +   +E D  QK   +L
Sbjct: 935  KQEIEKLNQTVNDLTNQINQTNQSLQNSANLYEEQVEQLQNDLNNRNKENDQLQKQTQQL 994

Query: 1258 RVQLSAFESKYEQLLDSVQSSTQEETNKIVTME-QVTSLQNKLQDKEEHL-RNLQEKYAD 1315
            +  L     + +  LD+  +  ++ T +   +E Q+   + KL DK  +L + LQ    +
Sbjct: 995  KDDLIGKIEQLQGDLDAANNKLKDTTQQKGDLEKQMNEEKQKLNDKINNLDQQLQNTQRE 1054

Query: 1316 VINQIEILRSEIEDEK 1331
               Q + L +E E  K
Sbjct: 1055 AQQQAKKLSNENEQLK 1070



 Score =  127 bits (307), Expect = 2e-27
 Identities = 183/866 (21%), Positives = 369/866 (42%), Gaps = 78/866 (9%)

Query: 297  KQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTES 356
            KQ +E + + K   +++    +    E T+  +L + LN  +R++++   + L       
Sbjct: 243  KQELERNSQLKHRYDDETIPSLMANHEETET-QLRDELNQSMRESDRIKRDLL----DRE 297

Query: 357  KAVSSPSKKGSPLISR-KSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQ 415
             A+ +  ++   L S  +S +N  +KM+   SQL SET    +    +  +  +     +
Sbjct: 298  NAIKTLKRQQRQLFSVCESLKNQNTKMEEELSQLRSETAMNASALSTSSVKYDEAMNEAK 357

Query: 416  SLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHV--GTNTE 473
              N+++   + V++                +  +AQL+   ++  +  + +    G    
Sbjct: 358  RANEEINQLQGVLNIAKNKVKKATQRADAAEKELAQLKRNEEEMQQSIADLTTSNGEKES 417

Query: 474  DVNEIAKVQEQLKQELNDEIKDVN-VKDLIEKLKSAEEQITQ-LND-EIDAAN-----KN 525
             + ++ +  +QLK +   + + +N ++  ++ +K+  E + + LN  +I+A N      N
Sbjct: 418  KLKDLREANKQLKNKCIQQNEQINELQHELDTIKAENESMQKKLNAAQIEAKNLQQSLTN 477

Query: 526  MIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTE----ELHHLSQKVAELEEEKGNL 581
                KS  + K   +  T   + K+     ++ +  E    ++  L QK+ + EEEK  L
Sbjct: 478  AFDEKSVLEEKADSLGTTAKEYEKLKQILNDLKQKKEKAEGQITDLEQKLEKSEEEKTAL 537

Query: 582  QLHLVDYDSGRMIESDVYKKMI----EMENLAETRLKAISLLESQKFDLVQELHILQQKY 637
               + +  +    E    K++I    EM+NL E ++     LE+Q  +L Q+L  L  + 
Sbjct: 538  DKTVKEQGNQIQREQAQIKQLIGENDEMQNLIEEKINDNKKLETQLKNLQQQLDQLSNEK 597

Query: 638  DEVE-----------DKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALV----- 681
             E++           DK   ISQL+SD    + K+  ++ + + ++A    L  +     
Sbjct: 598  AELQSNTTILQASLDDKNQKISQLKSDIQEKDAKAFDVQSEQEEMNAKLANLEKINDKHK 657

Query: 682  --IENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKI 739
              IE+LK        TI  +EN+K D+  +L    +    L  K E    +  ++ L + 
Sbjct: 658  KKIEDLKKQLGDSSATIVKVENEKNDLNEELGRLKKALESL--KQESQGYQDANKKLIEE 715

Query: 740  NHEEQSKIQTQFG----IDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSL 795
            N + +++I+ + G    +  +IQ     I   ES+L + +S++     ++   + +   L
Sbjct: 716  NEQLENQIKDKDGNIDKLSRQIQNHTNRISENESQLGEVQSQLDDAAMTVHSQDQKIQQL 775

Query: 796  ERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKN 855
            +R+  QL +  Q       E   Q   +  +LA   D  +       E E + +  Q++ 
Sbjct: 776  QRQLAQLTTQKQVSDDRIKELERQNQGIARKLANAKDELQTALHNNAENEDKIQSQQREL 835

Query: 856  QILLEENQNLQI----SLSDMQQHYNALVEKANRTD--------LAESESTKYQTQLRDL 903
             IL +E ++LQ     ++ D+    N   E+  +T+        + E+   K QT + DL
Sbjct: 836  DILHKEGESLQKRNQQTIDDLTNQLNKTKEELRQTEQQLRELQKMKENNDDKMQTAITDL 895

Query: 904  ESNLKRITH---------EHQTLIVQKKKEIEDLEIEFNTQ----IESAIRD-KKVLNEK 949
             S L R            E QT   Q+ KE  D +IE   Q    +   + D    +N+ 
Sbjct: 896  GSELDRTKAKLQATSRQLEQQTKQAQQDKEASDSQIENQKQEIEKLNQTVNDLTNQINQT 955

Query: 950  YEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQK-QQTQSP-DYTEQY 1007
             +         E Q+++ +N++ N N   ++L K   +L D  + K +Q Q   D     
Sbjct: 956  NQSLQNSANLYEEQVEQLQNDLNNRNKENDQLQKQTQQLKDDLIGKIEQLQGDLDAANNK 1015

Query: 1008 INEINKLNA-LLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQR 1066
            + +  +    L KQ +EE   LN KINN      +   + + +  + + + E ++ ++  
Sbjct: 1016 LKDTTQQKGDLEKQMNEEKQKLNDKINNLDQQLQNTQREAQQQAKKLSNENEQLKADLDS 1075

Query: 1067 VSKQLLDSKQHNEELQILVREQDDQI 1092
              K +   +Q N++L +  + Q D+I
Sbjct: 1076 AKKDIERYEQRNKDL-LQAKGQSDKI 1100



 Score =  116 bits (280), Expect = 4e-24
 Identities = 187/993 (18%), Positives = 407/993 (40%), Gaps = 58/993 (5%)

Query: 500  DLIEKLKSAEEQITQLNDEIDAANKNMIKVKSN-HKLKLKQMQKTIDNFSKVSDSNKEIV 558
            D +  + S  EQ+  L DE      N I   S   K ++ + QKTI +F+  +  +   +
Sbjct: 123  DRLRVIHSLTEQLKSLQDENSQLRVNSISSTSILQKSEISRPQKTIQDFNSPTFLH---I 179

Query: 559  RLTEELHHLSQKVAELE-EEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAIS 617
                ++  L +K+  L+ + K   +L      S +   + +  KMIE+    + R+ ++ 
Sbjct: 180  FAQVDVSDLDRKLKALQTDSKTASKLVNSLQKSFKQYTTQMKSKMIEIATQCKDRVDSVE 239

Query: 618  LLESQKFDLVQELHILQQKYDE--VEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASK 675
                Q+ +   +L   + +YD+  +   +A+  + ++ Q+  E+     E   D +    
Sbjct: 240  RRLKQELERNSQL---KHRYDDETIPSLMANHEETET-QLRDELNQSMRES--DRIKRDL 293

Query: 676  KELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISEL 735
             +    I+ LK  + QL+   + L+N    +  +L     E       L   S  K  E 
Sbjct: 294  LDRENAIKTLKRQQRQLFSVCESLKNQNTKMEEELSQLRSETAMNASALSTSSV-KYDEA 352

Query: 736  L--AKINHEEQSKIQTQFGIDA-KIQERDLYIENIESELSKYKSRICRLEESIAVMEDRR 792
            +  AK  +EE +++Q    I   K+++     +  E EL++ K     +++SIA +    
Sbjct: 353  MNEAKRANEEINQLQGVLNIAKNKVKKATQRADAAEKELAQLKRNEEEMQQSIADLTTSN 412

Query: 793  YSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQ 852
               E K   L    ++ +    +   Q +EL + L  +   +  ++K+L   + E K LQ
Sbjct: 413  GEKESKLKDLREANKQLKNKCIQQNEQINELQHELDTIKAENESMQKKLNAAQIEAKNLQ 472

Query: 853  KKNQILLEENQNLQI---SLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKR 909
            +      +E   L+    SL    + Y  L +  N  DL + +  K + Q+ DLE  L++
Sbjct: 473  QSLTNAFDEKSVLEEKADSLGTTAKEYEKLKQILN--DLKQKKE-KAEGQITDLEQKLEK 529

Query: 910  ITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKN 969
               E   L    K++   ++ E   QI+  I +   +    E+ I    +LE QL+  + 
Sbjct: 530  SEEEKTALDKTVKEQGNQIQRE-QAQIKQLIGENDEMQNLIEEKINDNKKLETQLKNLQQ 588

Query: 970  NIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALN 1029
             ++ L+    EL   N  ++   +   + Q     +  I E +     ++ + EE+ A  
Sbjct: 589  QLDQLSNEKAELQS-NTTILQASLD-DKNQKISQLKSDIQEKDAKAFDVQSEQEEMNAKL 646

Query: 1030 QKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQD 1089
              +      +   + D + +L   +  +  +E E   ++++L   K+  E L+   +   
Sbjct: 647  ANLEKINDKHKKKIEDLKKQLGDSSATIVKVENEKNDLNEELGRLKKALESLKQESQGYQ 706

Query: 1090 DQIKELKETKLTFEMNIPKTEGMI--ISSTIEPMSD--DANNVDXXXXXXXXXXXXLKVQ 1145
            D  K+L E     E  I   +G I  +S  I+  ++    N               + V 
Sbjct: 707  DANKKLIEENEQLENQIKDKDGNIDKLSRQIQNHTNRISENESQLGEVQSQLDDAAMTVH 766

Query: 1146 EEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTG--------------HDVV 1191
             +++ IQ+   LQ Q A+L T+ Q    +I +LE  N  +                ++  
Sbjct: 767  SQDQKIQQ---LQRQLAQLTTQKQVSDDRIKELERQNQGIARKLANAKDELQTALHNNAE 823

Query: 1192 NQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQ 1251
            N+++I   + +L+ L+ E ++L     +    +++ +++   E+ +  +Q L + +   +
Sbjct: 824  NEDKIQSQQRELDILHKEGESLQKRNQQTIDDLTNQLNKTKEELRQT-EQQLRELQKMKE 882

Query: 1252 KTEHELRVQLSAFESKYEQLLDSVQSSTQ--EETNKIVTMEQVTSLQNKLQDKEEHLRNL 1309
              + +++  ++   S+ ++    +Q++++  E+  K    ++  S  ++++++++ +  L
Sbjct: 883  NNDDKMQTAITDLGSELDRTKAKLQATSRQLEQQTKQAQQDKEAS-DSQIENQKQEIEKL 941

Query: 1310 QEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXD---LRTENQSYKQ----M 1362
             +   D+ NQI      +++    +                +   L+ + Q  K      
Sbjct: 942  NQTVNDLTNQINQTNQSLQNSANLYEEQVEQLQNDLNNRNKENDQLQKQTQQLKDDLIGK 1001

Query: 1363 QEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHE 1422
             EQ   +++  N +LK ++                   K+  L  QL+    E  Q+  +
Sbjct: 1002 IEQLQGDLDAANNKLKDTTQQKGDLEKQMNEEKQKLNDKINNLDQQLQNTQREAQQQAKK 1061

Query: 1423 YTITLTQRNDEFENVRQQLVEYEKRIEDLTYEK 1455
             +    Q   + ++ ++ +  YE+R +DL   K
Sbjct: 1062 LSNENEQLKADLDSAKKDIERYEQRNKDLLQAK 1094



 Score =  107 bits (256), Expect = 3e-21
 Identities = 176/996 (17%), Positives = 414/996 (41%), Gaps = 63/996 (6%)

Query: 634  QQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLY 693
            ++K   ++     I  + SD +  ++    L+EQI +   S++   L+ + L   +EQ  
Sbjct: 26   ERKKSFIKSLQDSIKSISSDLIVRQL----LQEQISSNYLSQRIDELISKMLNDGREQFI 81

Query: 694  GTIKDLENDKEDIMNKLQNYIQENM-----DLTDKLEKMSAEKISELLA-----KINHEE 743
             T+    N  E I N  +  +   M        D     SA+++  + +     K   +E
Sbjct: 82   DTLIQKINKYEAIFNDERTELLRVMGDRVLSFADSQITTSADRLRVIHSLTEQLKSLQDE 141

Query: 744  QSKIQTQFGIDAKIQERDLYIENIESELSKYKS-RICRLEESIAVME-DRRY-SLERKAD 800
             S+++        I ++   I   +  +  + S     +   + V + DR+  +L+  + 
Sbjct: 142  NSQLRVNSISSTSILQKS-EISRPQKTIQDFNSPTFLHIFAQVDVSDLDRKLKALQTDSK 200

Query: 801  QLGSYLQEKQKAYSEYTIQ-EDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKK--NQI 857
                 +   QK++ +YT Q + +++       D    VE++L +    N +L+ +  ++ 
Sbjct: 201  TASKLVNSLQKSFKQYTTQMKSKMIEIATQCKDRVDSVERRLKQELERNSQLKHRYDDET 260

Query: 858  LLEENQNLQISLSDMQQHYNALVEKANRT--DLAESEST--KYQTQLRDLESNLKRITHE 913
            +     N + + + ++   N  + +++R   DL + E+     + Q R L S  + + ++
Sbjct: 261  IPSLMANHEETETQLRDELNQSMRESDRIKRDLLDRENAIKTLKRQQRQLFSVCESLKNQ 320

Query: 914  HQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIEN 973
            +  +  +  +   +  +  +    S+++  + +NE    N E + QL+  L   KN ++ 
Sbjct: 321  NTKMEEELSQLRSETAMNASALSTSSVKYDEAMNEAKRAN-EEINQLQGVLNIAKNKVKK 379

Query: 974  LNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALL---KQKDEEIIALNQ 1030
                 +   K  L  + ++ ++ Q    D T     + +KL  L    KQ   + I  N+
Sbjct: 380  ATQRADAAEK-ELAQLKRNEEEMQQSIADLTTSNGEKESKLKDLREANKQLKNKCIQQNE 438

Query: 1031 KINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDD 1090
            +IN  Q    ++ ++ ES   +     +   + +Q+      D K   EE    +     
Sbjct: 439  QINELQHELDTIKAENESMQKKLNAA-QIEAKNLQQSLTNAFDEKSVLEEKADSLGTTAK 497

Query: 1091 QIKELKETKLTFEMNIPKTEGMI--ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEE 1148
            + ++LK+     +    K EG I  +   +E   ++   +D             + Q ++
Sbjct: 498  EYEKLKQILNDLKQKKEKAEGQITDLEQKLEKSEEEKTALDKTVKEQGNQIQREQAQIKQ 557

Query: 1149 ---EFIQERSVLQEQ---SAKLNTELQECYTKIIQLETLNTELTGHDVVNQ-------EQ 1195
               E  + +++++E+   + KL T+L+    ++ QL     EL  +  + Q       ++
Sbjct: 558  LIGENDEMQNLIEEKINDNKKLETQLKNLQQQLDQLSNEKAELQSNTTILQASLDDKNQK 617

Query: 1196 INQLKSKLEQLNTENDNLLSTVAELRSSISSAV---DQRGFEIAELWKQHLAQREADFQK 1252
            I+QLKS +++ + +  ++ S   E+ + +++     D+   +I +L KQ L    A   K
Sbjct: 618  ISQLKSDIQEKDAKAFDVQSEQEEMNAKLANLEKINDKHKKKIEDLKKQ-LGDSSATIVK 676

Query: 1253 TEHELRVQLSAFESKYEQLLDSVQSSTQ--EETNKIVTMEQVTSLQNKLQDKEEHLRNLQ 1310
             E+E +  L+    + ++ L+S++  +Q  ++ NK + +E+   L+N+++DK+ ++  L 
Sbjct: 677  VENE-KNDLNEELGRLKKALESLKQESQGYQDANKKL-IEENEQLENQIKDKDGNIDKLS 734

Query: 1311 EKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQ--SYKQMQEQSIL 1368
             +  +  N+I    S++ + +                     R   Q  + KQ+ +  I 
Sbjct: 735  RQIQNHTNRISENESQLGEVQSQLDDAAMTVHSQDQKIQQLQRQLAQLTTQKQVSDDRIK 794

Query: 1369 NINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLEL--KDSEIYQKTHEYTIT 1426
             +  +N  + +                 + E K+     +L++  K+ E  QK ++ TI 
Sbjct: 795  ELERQNQGIARKLANAKDELQTALHNNAENEDKIQSQQRELDILHKEGESLQKRNQQTID 854

Query: 1427 -----LTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESE 1481
                 L +  +E     QQL E +K  E+   + ++ +  L  ++       +   ++ E
Sbjct: 855  DLTNQLNKTKEELRQTEQQLRELQKMKENNDDKMQTAITDLGSELDRTKAKLQATSRQLE 914

Query: 1482 IERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEIT 1541
             +  +  ++     ++  +  +++ +LN+ + +   + N+   +L+N         +++ 
Sbjct: 915  QQTKQAQQDKEASDSQIENQKQEIEKLNQTVNDLTNQINQTNQSLQNSANLYEEQVEQLQ 974

Query: 1542 NLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMN 1577
            N  N     + ++QK      D   G+ EQL   ++
Sbjct: 975  NDLNNRNKENDQLQKQTQQLKDDLIGKIEQLQGDLD 1010



 Score = 99.1 bits (236), Expect = 9e-19
 Identities = 175/908 (19%), Positives = 373/908 (41%), Gaps = 80/908 (8%)

Query: 55   ERAQKCLENAALVSKRIKEHRKATAELLGRPFVPGISESLANTLKQKEILMEKIKQYKEL 114
            E A +C +    V +R+K+  +  ++L  R     I   +AN  + +  L +++ Q    
Sbjct: 226  EIATQCKDRVDSVERRLKQELERNSQLKHRYDDETIPSLMANHEETETQLRDELNQSMRE 285

Query: 115  SKRSSTTIV-RXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKD--NALSVLQVKMKIMETT 171
            S R    ++ R                + +     NT  E++     S   +    + T+
Sbjct: 286  SDRIKRDLLDRENAIKTLKRQQRQLFSVCESLKNQNTKMEEELSQLRSETAMNASALSTS 345

Query: 172  ILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAE 231
             +   E +NE  +  E  N+                    +  ++++ +++ N    E E
Sbjct: 346  SVKYDEAMNEAKRANEEINQ-LQGVLNIAKNKVKKATQRADAAEKELAQLKRN----EEE 400

Query: 232  WKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELE------QXXXXX 285
             +     L      K+ ++  L EANK L+    + + + ++L  EL+      +     
Sbjct: 401  MQQSIADLTTSNGEKESKLKDLREANKQLKNKCIQQNEQINELQHELDTIKAENESMQKK 460

Query: 286  XXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKEL 345
                       +QS+  + +EK+ +EEK      ++    K+ E L+ +   ++Q  ++ 
Sbjct: 461  LNAAQIEAKNLQQSLTNAFDEKSVLEEKAD----SLGTTAKEYEKLKQILNDLKQKKEKA 516

Query: 346  ENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSET--LNQDTDKKIN 403
            E ++  +  E K   S  +K +   + K   N   + ++   QL  E   +    ++KIN
Sbjct: 517  EGQITDL--EQKLEKSEEEKTALDKTVKEQGNQIQREQAQIKQLIGENDEMQNLIEEKIN 574

Query: 404  KNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQ----- 458
             N+  KLE  +++L + L       +E  +           K+  I+QL+ + Q+     
Sbjct: 575  DNK--KLETQLKNLQQQLDQLSNEKAELQSNTTILQASLDDKNQKISQLKSDIQEKDAKA 632

Query: 459  ---HMEGPSLIHVGTNTEDVNEIAKVQ-EQLKQELNDE----IKDVNVK-DLIE---KLK 506
                 E   +     N E +N+  K + E LK++L D     +K  N K DL E   +LK
Sbjct: 633  FDVQSEQEEMNAKLANLEKINDKHKKKIEDLKKQLGDSSATIVKVENEKNDLNEELGRLK 692

Query: 507  SAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFS--------KVSDSNKEIV 558
             A E + Q +     ANK +I+     + ++K     ID  S        ++S++  ++ 
Sbjct: 693  KALESLKQESQGYQDANKKLIEENEQLENQIKDKDGNIDKLSRQIQNHTNRISENESQLG 752

Query: 559  RLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISL 618
             +  +L   +  V   +++   LQ  L    + + +  D  K+ +E +N    R      
Sbjct: 753  EVQSQLDDAAMTVHSQDQKIQQLQRQLAQLTTQKQVSDDRIKE-LERQNQGIAR-----K 806

Query: 619  LESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKEL 678
            L + K +L   LH   +  D+++ +  ++  L  +    E      ++ ID L+    +L
Sbjct: 807  LANAKDELQTALHNNAENEDKIQSQQRELDILHKE---GESLQKRNQQTIDDLT---NQL 860

Query: 679  ALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAK 738
                E L+  ++QL    ++L+  KE+  +K+Q  I    DL  +L++  A K+     +
Sbjct: 861  NKTKEELRQTEQQL----RELQKMKENNDDKMQTAI---TDLGSELDRTKA-KLQATSRQ 912

Query: 739  INHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERK 798
            +  + +   Q +   D++I+ +   IE +   ++   ++I +  +S   +++     E +
Sbjct: 913  LEQQTKQAQQDKEASDSQIENQKQEIEKLNQTVNDLTNQINQTNQS---LQNSANLYEEQ 969

Query: 799  ADQLGSYLQEKQKAYSEYTIQ----EDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKK 854
             +QL + L  + K   +   Q    +D+L+ ++  L         +L +   +  +L+K+
Sbjct: 970  VEQLQNDLNNRNKENDQLQKQTQQLKDDLIGKIEQLQGDLDAANNKLKDTTQQKGDLEKQ 1029

Query: 855  NQILLEENQNLQISLSDM-QQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHE 913
               + EE Q L   ++++ QQ  N   E   +     +E+ + +  L   + +++R    
Sbjct: 1030 ---MNEEKQKLNDKINNLDQQLQNTQREAQQQAKKLSNENEQLKADLDSAKKDIERYEQR 1086

Query: 914  HQTLIVQK 921
            ++ L+  K
Sbjct: 1087 NKDLLQAK 1094



 Score = 93.5 bits (222), Expect = 4e-17
 Identities = 164/838 (19%), Positives = 354/838 (42%), Gaps = 84/838 (10%)

Query: 212  EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271
            E  K Q TKM+E    + +E       L       D  ++  + AN+ +   +  +++  
Sbjct: 315  ESLKNQNTKMEEELSQLRSETAMNASALSTSSVKYDEAMNEAKRANEEINQLQGVLNIAK 374

Query: 272  SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELL 331
            +K+ +  ++                ++ ++ S  + T    +   ++ ++ E  K+   L
Sbjct: 375  NKVKKATQRADAAEKELAQLKRN--EEEMQQSIADLTTSNGEKESKLKDLREANKQ---L 429

Query: 332  EHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSS 391
            ++   Q  +   EL+++L T+  E++  S   K  +  I  K+ + + +      S L  
Sbjct: 430  KNKCIQQNEQINELQHELDTIKAENE--SMQKKLNAAQIEAKNLQQSLTNAFDEKSVLEE 487

Query: 392  ETLNQDTDKKINKNEIAKLEMVIQSLNK-------DLVDKEYVI--SEKDTXXXXXXXXX 442
            +  +  T  K    E  KL+ ++  L +        + D E  +  SE++          
Sbjct: 488  KADSLGTTAK----EYEKLKQILNDLKQKKEKAEGQITDLEQKLEKSEEEKTALDKTVKE 543

Query: 443  XGKDTLIAQLQLEH--QQHMEGPSLIH--VGTNTEDVNEIAKVQEQLKQELNDEIK-DVN 497
             G      Q Q++    ++ E  +LI   +  N +   ++  +Q+QL Q  N++ +   N
Sbjct: 544  QGNQIQREQAQIKQLIGENDEMQNLIEEKINDNKKLETQLKNLQQQLDQLSNEKAELQSN 603

Query: 498  VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSN-KE 556
               L   L    ++I+QL  +I   +     V+S      ++M   + N  K++D + K+
Sbjct: 604  TTILQASLDDKNQKISQLKSDIQEKDAKAFDVQSEQ----EEMNAKLANLEKINDKHKKK 659

Query: 557  IVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAI 616
            I  L ++L   S  + ++E EK +L   L     GR+      KK +E       + ++ 
Sbjct: 660  IEDLKKQLGDSSATIVKVENEKNDLNEEL-----GRL------KKALE-----SLKQESQ 703

Query: 617  SLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSV-HLEEQIDALSASK 675
               ++ K  L++E    +Q  ++++DK  +I +L S Q+ +    +   E Q+  + +  
Sbjct: 704  GYQDANK-KLIEE---NEQLENQIKDKDGNIDKL-SRQIQNHTNRISENESQLGEVQSQL 758

Query: 676  KELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISEL 735
             + A+ + +     +QL   +  L   K+   ++++   ++N  +  KL     E  + L
Sbjct: 759  DDAAMTVHSQDQKIQQLQRQLAQLTTQKQVSDDRIKELERQNQGIARKLANAKDELQTAL 818

Query: 736  LAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSL 795
                N E + KIQ+        Q+R+L I + E E S  K    R +++I  + ++    
Sbjct: 819  --HNNAENEDKIQS--------QQRELDILHKEGE-SLQK----RNQQTIDDLTNQLNKT 863

Query: 796  ERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRV-VEKQLLEIEHENKELQKK 854
            + +  Q    L+E QK       +    +  L   +D  +  ++    ++E + K+ Q+ 
Sbjct: 864  KEELRQTEQQLRELQKMKENNDDKMQTAITDLGSELDRTKAKLQATSRQLEQQTKQAQQD 923

Query: 855  NQILLEENQNLQISLSDMQQHYNALVEKANRTDLA-ESESTKYQTQLRDLESNLKRITHE 913
             +    + +N +  +  + Q  N L  + N+T+ + ++ +  Y+ Q+  L+++L     E
Sbjct: 924  KEASDSQIENQKQEIEKLNQTVNDLTNQINQTNQSLQNSANLYEEQVEQLQNDLNNRNKE 983

Query: 914  HQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIEN 973
            +     Q +K+ + L+ +   +IE    D    N K +   +    LE Q+ E K   + 
Sbjct: 984  ND----QLQKQTQQLKDDLIGKIEQLQGDLDAANNKLKDTTQQKGDLEKQMNEEK---QK 1036

Query: 974  LNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQK 1031
            LN   +++N      +D+ +Q  Q ++    ++  NE  +L A L    ++I    Q+
Sbjct: 1037 LN---DKINN-----LDQQLQNTQREAQQQAKKLSNENEQLKADLDSAKKDIERYEQR 1086


>UniRef50_UPI0000F1FE72 Cluster: PREDICTED: hypothetical protein; n=2;
            Danio rerio|Rep: PREDICTED: hypothetical protein - Danio
            rerio
          Length = 1889

 Score =  138 bits (334), Expect = 1e-30
 Identities = 246/1246 (19%), Positives = 531/1246 (42%), Gaps = 127/1246 (10%)

Query: 387  SQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKD 446
            +Q++S    Q  D + ++  I  L   ++ L+      E  + EK+             D
Sbjct: 446  AQVASLRSQQIKDAEKHQLVITNLNKQLKGLSSTQECLESSLMEKEHTLARTSEKLECID 505

Query: 447  TLIAQLQLEHQQHME-GPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVK-----D 500
            +L   L+ + +Q+ +    L+    N  +V +     E+   E+   + ++ +K     D
Sbjct: 506  SLREALEAKEKQNQDQADRLLQSEHNLAEVKKTCSNFEKENSEMKAAVAELTLKLGVMKD 565

Query: 501  LIEK----LKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKV-SDSNK 555
              +K    ++S +  + Q NDE+D  N   ++ ++     L+  ++ ID    V +D +K
Sbjct: 566  KSQKQDTAIESLQSDLVQTNDELDRLNTVHLEERAQLVHDLQSCEREIDRLQDVITDKDK 625

Query: 556  EIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKA 615
            EI+ L+  +   S+++ EL++E                ++ DV  K+   EN+   R   
Sbjct: 626  EILALSSSMAEYSEQIHELKQEM--------------KLKEDVLTKV--EENVQIFRDPQ 669

Query: 616  ISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASK 675
            +S  + Q F+++    I Q K  E + K+A   + +S+   +EIK    + + D     K
Sbjct: 670  LS--DQQFFNILIPKLIEQLKKTESDLKVA---KKESESRSNEIKDFIKQTEDD-----K 719

Query: 676  KELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISEL 735
            K    +I++L+++ ++L   +K+ ++D E +  K  ++++E  +    L ++S +K   L
Sbjct: 720  K----IIQDLRMEIQKLQINLKEPQSDGEQVHEK--DFLKEERNKL--LSEVSKQKSELL 771

Query: 736  LAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRIC----RLEESIAVMEDR 791
                  EEQ   Q Q   D  IQ++   I ++E +L   +  +     R    + + ++ 
Sbjct: 772  RFSKTIEEQVACQEQLKQD--IQDKSEVIFSLEQKLKIVQEELVVERDRFNSELTIRDEA 829

Query: 792  RYSLER----KADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHE 847
            +  LE+    + D + S   + QK          EL ++  +L      +E Q L+ ++ 
Sbjct: 830  KEHLEKSLSCEIDSVKSVKNDNQKLKESLEQNLGELASQKQLL--DSAAIEIQALQDQNS 887

Query: 848  N-----KELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTK----YQT 898
            +     K L+  N  L  E +    SLSD+ +    L+ K ++ +L  SES K    +Q 
Sbjct: 888  SLIFQVKSLESDNCHLRVEIETRVQSLSDVSEEKKRLLNKISQIELQLSESVKTISDFQR 947

Query: 899  QLRDL---ESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNI- 954
               +L   E++LK+   +++  I +   E + +    N  I+   + +++L+EK ++ + 
Sbjct: 948  DKEELYLREADLKKELEKNKQSITEISLEKDGVVELHNALIKQNQQLQEILDEKQKEALV 1007

Query: 955  --EYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEIN 1012
              + V+ L  ++       E L   +  L++ N  L  + + +Q     + T++     N
Sbjct: 1008 LTQAVSDLNNKITITLKENEKLASQIVSLDEQNGSL-QRQINEQMKSLTETTKERETLQN 1066

Query: 1013 KLNALLKQKDEEIIALNQKINNAQVSYMSMVSDY---ESKLAQFTTKLENMEEEMQRVSK 1069
            K+    + +D E   + + +  A+   +  V ++   E KL      L+    E   +++
Sbjct: 1067 KIQ-FFETQDVENHKIIEGLLKAKEDLLLQVEEHKVIEQKLQANAEMLQKKSSECTDLTQ 1125

Query: 1070 QLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVD 1129
             L ++K+  + L+  +   + ++ + K   L  E  I   + M I +  +      +N+ 
Sbjct: 1126 GLSETKEEVDHLKRKLESSNSEVVKCKNIMLEKE-KILTDQRMQIEAYQQQFKHLQDNIS 1184

Query: 1130 XXXXXXXXXXXXLKVQEEEEFIQERS----VLQEQSAK----LNTELQECYTKIIQLETL 1181
                        L   E++  +Q+ S    +LQ++       + T  QE  +  ++   L
Sbjct: 1185 VLQEQAFKHKSGLT--EKDTLLQKESNACVLLQKELGHERELVFTSQQEISSLKVECSRL 1242

Query: 1182 NTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAEL---RSSISSAVDQRGFEIAEL 1238
            N  L   +   +E+  + ++ LE+L   N+ L+S  ++L    +SI+  ++     + + 
Sbjct: 1243 NQALEEKENTLREKNLECQNHLEELCKRNETLVSLTSQLGLMNASIAK-LESDNANLKDT 1301

Query: 1239 WKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTM----EQVTS 1294
             ++HL++  A  ++   + +++L  ++   + + D       E  N +  M    E +TS
Sbjct: 1302 LERHLSE-SARLKEELMQKQIELVEYQDSGQAMNDQNSIIKSELKNSMTEMVRQKEMITS 1360

Query: 1295 LQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXD--- 1351
            LQN+L+ K   L +L+EK+    +Q+E L+  + D++  F                    
Sbjct: 1361 LQNELESKRVKLGSLEEKFKSEHSQLEALQLTLRDKEDVFQTQEMHVNNMQAKLLESEGQ 1420

Query: 1352 -------LRTENQSYKQMQEQSILNINEENAQLKKSSXXXXX-------XXXXXXXRVND 1397
                   L+ ENQS +   E      +     L   S                    + +
Sbjct: 1421 IKQRILKLQEENQSLRTALEDKDKEFSLVKTTLLAQSEACESRLKSEMVATAQFQREIQN 1480

Query: 1398 AEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQ------QLVEYEKRIEDL 1451
             + K+ +L   +  KDS + Q+  +Y    +  ++    V Q      QL    K++ + 
Sbjct: 1481 LQEKMNQLISIITEKDSLLMQEKEKYMCLQSSASELESTVSQLNCQIKQLTSEIKQLRET 1540

Query: 1452 TYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKA 1511
              +KE      + +M +    Y+ +Q+E ++ + +L++ LN K  +   + K + E    
Sbjct: 1541 QTKKEQVTFAAQSQMQKLDELYKNLQQECDLTKQELLKVLNEKSLKEEEVRKLILE---- 1596

Query: 1512 LEEEVAKTN--EMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQ 1555
             +E++ +T+  ++QT  + Q     T  +++  +Q M +    K++
Sbjct: 1597 -KEDILRTSSYQIQTTQDQQHNWRSTTMNKVEEVQAMEKKKLHKME 1641



 Score =  117 bits (281), Expect = 3e-24
 Identities = 226/1176 (19%), Positives = 483/1176 (41%), Gaps = 101/1176 (8%)

Query: 477  EIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLN--DEIDAANKNMIKVKSNHK 534
            E+ KVQ  +   ++ ++  ++ + + E  +  EE +++L   +++ A N+ + K    +K
Sbjct: 194  ELKKVQSGICVNMSPDVTSLHSR-ITELQEEREEMLSKLELYEDMKAKNEELRKQLMEYK 252

Query: 535  LKLKQMQKTIDNFSKVSDSNKEIVRLTE-ELHHLSQKVAELEE-EKGNLQLHLVDYDSGR 592
             +  +MQ  ++  +K + S      + + ++    + V  + E E+G  Q H  +  + R
Sbjct: 253  EQQSKMQADLEQVTKRASSQASETGMDDVQVMEWQEMVTMVTEAERGRDQGHEKNVMAFR 312

Query: 593  MIESDVYKKMI-EMENLAETRLKAISLLESQKFDLVQEL--HILQQKYDEVEDKLADISQ 649
            M   +  ++ +   +   E  L  +  L  QK    +      LQ+++   +D + D+  
Sbjct: 313  MSHIEEEREALANRQQEVEEELAQVHGLCPQKSRKPKYFTPRSLQEEFHNTQDPMGDMDH 372

Query: 650  LQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNK 709
               D + +         Q  A  A    L  V+E L+L++ QL   I  LE   +D+ ++
Sbjct: 373  ---DGLINGENMGGWWPQHSA--ADTDGLRSVVEELELERNQLQEQILVLEKQCQDLEDR 427

Query: 710  LQNYIQENMDLTD-KLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIE 768
            LQ  +Q  ++L   + E++ A+  S    +I   E+ ++     ++ +++      E +E
Sbjct: 428  LQ--LQARIELLQHESERLQAQVASLRSQQIKDAEKHQLVIT-NLNKQLKGLSSTQECLE 484

Query: 769  SELSKYKSRICRLEESIAVMEDRRYSLERKA----DQLGSYLQEK-------------QK 811
            S L + +  + R  E +  ++  R +LE K     DQ    LQ +             +K
Sbjct: 485  SSLMEKEHTLARTSEKLECIDSLREALEAKEKQNQDQADRLLQSEHNLAEVKKTCSNFEK 544

Query: 812  AYSEYTIQEDELVNRLAVLMD----HDRVVEKQLLEIEHENKELQKKNQILLEENQNLQI 867
              SE      EL  +L V+ D     D  +E    ++   N EL + N + LEE   L  
Sbjct: 545  ENSEMKAAVAELTLKLGVMKDKSQKQDTAIESLQSDLVQTNDELDRLNTVHLEERAQLVH 604

Query: 868  SLSDMQQHYNALVEKANRTD---LAESES-TKYQTQLRDLESNLKR----ITHEHQTLIV 919
             L   ++  + L +     D   LA S S  +Y  Q+ +L+  +K     +T   + + +
Sbjct: 605  DLQSCEREIDRLQDVITDKDKEILALSSSMAEYSEQIHELKQEMKLKEDVLTKVEENVQI 664

Query: 920  QKKKEIEDLEIEFNTQIESAIR-------DKKVLNEKYEKNIEYVTQLEAQLQEYKNNIE 972
             +  ++ D +  FN  I   I        D KV  ++ E     +     Q ++ K  I+
Sbjct: 665  FRDPQLSDQQF-FNILIPKLIEQLKKTESDLKVAKKESESRSNEIKDFIKQTEDDKKIIQ 723

Query: 973  NLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKI 1032
            +L M   E+ K+ + L +     +Q    D+ ++   E NKL + + ++  E++  ++ I
Sbjct: 724  DLRM---EIQKLQINLKEPQSDGEQVHEKDFLKE---ERNKLLSEVSKQKSELLRFSKTI 777

Query: 1033 NNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLL-DSKQHNEELQILVREQDDQ 1091
                     +  D + K    +  + ++E++++ V ++L+ +  + N EL I      D+
Sbjct: 778  EEQVACQEQLKQDIQDK----SEVIFSLEQKLKIVQEELVVERDRFNSELTIR-----DE 828

Query: 1092 IKELKETKLTFEMNIPKT---EGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEE 1148
             KE  E  L+ E++  K+   +   +  ++E    +  +              L+ Q   
Sbjct: 829  AKEHLEKSLSCEIDSVKSVKNDNQKLKESLEQNLGELASQKQLLDSAAIEIQALQDQNSS 888

Query: 1149 EFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNT 1208
               Q +S L+  +  L  E++     +  +      L       + Q+++    +     
Sbjct: 889  LIFQVKS-LESDNCHLRVEIETRVQSLSDVSEEKKRLLNKISQIELQLSESVKTISDFQR 947

Query: 1209 ENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKY 1268
            + + L    A+L+  +    +++      L K  + +      K   +L+  L   E + 
Sbjct: 948  DKEELYLREADLKKELEK--NKQSITEISLEKDGVVELHNALIKQNQQLQEILD--EKQK 1003

Query: 1269 EQLLDSVQSSTQEETNKI-VTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEI 1327
            E L+  +  +  +  NKI +T+++   L +++   +E   +LQ +  + +  +     E 
Sbjct: 1004 EALV--LTQAVSDLNNKITITLKENEKLASQIVSLDEQNGSLQRQINEQMKSLTETTKER 1061

Query: 1328 EDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNIN-EENAQL--KKSSXXX 1384
            E  +                    L+ +     Q++E  ++    + NA++  KKSS   
Sbjct: 1062 ETLQNKIQFFETQDVENHKIIEGLLKAKEDLLLQVEEHKVIEQKLQANAEMLQKKSSECT 1121

Query: 1385 XXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTH---EYTITLTQRNDEFENVRQQL 1441
                      +++ + +V  L  +LE  +SE+ +  +   E    LT +  + E  +QQ 
Sbjct: 1122 DLTQG-----LSETKEEVDHLKRKLESSNSEVVKCKNIMLEKEKILTDQRMQIEAYQQQF 1176

Query: 1442 VEYEKRI---EDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITES 1498
               +  I   ++  ++ +S L      + + +N    +QKE   ER    E +     E 
Sbjct: 1177 KHLQDNISVLQEQAFKHKSGLTEKDTLLQKESNACVLLQKELGHER----ELVFTSQQEI 1232

Query: 1499 VSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHV 1558
             SL  + + LN+ALEE+     E     +N   E+   N+ + +L + +   ++ I K  
Sbjct: 1233 SSLKVECSRLNQALEEKENTLREKNLECQNHLEELCKRNETLVSLTSQLGLMNASIAKLE 1292

Query: 1559 SFASDTKQGRDEQLDNTMNKELLDAVPRAELDLAMY 1594
            S  ++ K   +  L    +  L + + + +++L  Y
Sbjct: 1293 SDNANLKDTLERHLSE--SARLKEELMQKQIELVEY 1326



 Score = 99.1 bits (236), Expect = 9e-19
 Identities = 218/1069 (20%), Positives = 435/1069 (40%), Gaps = 83/1069 (7%)

Query: 147  LSNTIKEKDNAL---SVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXX 203
            LS   K+K   L     ++ ++   E    D+Q+K +E    +E K K            
Sbjct: 760  LSEVSKQKSELLRFSKTIEEQVACQEQLKQDIQDK-SEVIFSLEQKLKIVQEELVVERDR 818

Query: 204  XXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAA 263
                    ++ K+ + K     I      K++ Q+L + +E     +  L    +LL++A
Sbjct: 819  FNSELTIRDEAKEHLEKSLSCEIDSVKSVKNDNQKLKESLEQN---LGELASQKQLLDSA 875

Query: 264  RFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAK--QSIEPSCEEKTEIEEKGSLEIANM 321
              EI     + +  + Q              +    QS+    EEK  +  K S     +
Sbjct: 876  AIEIQALQDQNSSLIFQVKSLESDNCHLRVEIETRVQSLSDVSEEKKRLLNKISQIELQL 935

Query: 322  TELTKKIELL----EHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRN 377
            +E  K I       E L  +     KELE    ++   S       +  + LI +     
Sbjct: 936  SESVKTISDFQRDKEELYLREADLKKELEKNKQSITEISLEKDGVVELHNALIKQNQQLQ 995

Query: 378  TASKMKSPWSQLSSETLNQDTDK-KINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXX 436
                 K   + + ++ ++   +K  I   E  KL   I SL++     +  I+E+     
Sbjct: 996  EILDEKQKEALVLTQAVSDLNNKITITLKENEKLASQIVSLDEQNGSLQRQINEQ---MK 1052

Query: 437  XXXXXXXGKDTLIAQLQLEHQQHMEGPSLIH-VGTNTEDVN---EIAKVQEQLKQELNDE 492
                    ++TL  ++Q    Q +E   +I  +    ED+    E  KV EQ K + N E
Sbjct: 1053 SLTETTKERETLQNKIQFFETQDVENHKIIEGLLKAKEDLLLQVEEHKVIEQ-KLQANAE 1111

Query: 493  I---KDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSK 549
            +   K     DL + L   +E++  L  +++++N  ++K K N  L+ +++         
Sbjct: 1112 MLQKKSSECTDLTQGLSETKEEVDHLKRKLESSNSEVVKCK-NIMLEKEKI--------- 1161

Query: 550  VSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESD----VYKKMIEM 605
            ++D   +I    ++  HL   ++ L+E+    +  L + D+    ES+    + K++   
Sbjct: 1162 LTDQRMQIEAYQQQFKHLQDNISVLQEQAFKHKSGLTEKDTLLQKESNACVLLQKELGHE 1221

Query: 606  ENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKS-VHL 664
              L  T  + IS L+ +   L Q L   ++K + + +K  +  Q   +++C   ++ V L
Sbjct: 1222 RELVFTSQQEISSLKVECSRLNQAL---EEKENTLREKNLEC-QNHLEELCKRNETLVSL 1277

Query: 665  EEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKL 724
              Q+  ++AS  +L     NLK   + L   + +    KE++M K Q  + E  D    +
Sbjct: 1278 TSQLGLMNASIAKLESDNANLK---DTLERHLSESARLKEELMQK-QIELVEYQDSGQAM 1333

Query: 725  EKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEES 784
               ++   SEL   +    + K +    +  +++ + + + ++E +     S++  L+ +
Sbjct: 1334 NDQNSIIKSELKNSMTEMVRQK-EMITSLQNELESKRVKLGSLEEKFKSEHSQLEALQLT 1392

Query: 785  IAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQ-EDELVNRLAVLMDHDRVVE--KQL 841
            +   ED   + E   + + + L E +    +  ++ ++E  +    L D D+     K  
Sbjct: 1393 LRDKEDVFQTQEMHVNNMQAKLLESEGQIKQRILKLQEENQSLRTALEDKDKEFSLVKTT 1452

Query: 842  LEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTD-LAESESTKY---Q 897
            L  + E  E + K++++       Q  + ++Q+  N L+      D L   E  KY   Q
Sbjct: 1453 LLAQSEACESRLKSEMVA--TAQFQREIQNLQEKMNQLISIITEKDSLLMQEKEKYMCLQ 1510

Query: 898  TQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYV 957
            +   +LES + ++  + + L   + K++ + + +      +A    + L+E Y KN++  
Sbjct: 1511 SSASELESTVSQLNCQIKQL-TSEIKQLRETQTKKEQVTFAAQSQMQKLDELY-KNLQQE 1568

Query: 958  TQLEAQLQEYKNNIENLNMNVEELNKMNLELID------KHVQKQQTQSPDYTEQYINEI 1011
              L  Q  E    +   ++  EE+ K+ LE  D        +Q  Q Q  ++    +N++
Sbjct: 1569 CDLTKQ--ELLKVLNEKSLKEEEVRKLILEKEDILRTSSYQIQTTQDQQHNWRSTTMNKV 1626

Query: 1012 NKLNALLKQK--DEEIIALNQK---------INNAQVSYMSMVSDYESKLAQFTTKLENM 1060
             ++ A+ K+K    E +AL  K         +N         +   E  L Q   KL+  
Sbjct: 1627 EEVQAMEKKKLHKMEFMALQGKEASSDQWVQLNGHLQQCQLEIQQRECGLQQLNIKLQQT 1686

Query: 1061 EEEMQRVSKQLLDSKQHNEELQILVREQDDQIK-ELKETKLTFEMNIPK-TEGMIISSTI 1118
             EE + VS+ L D++Q   ELQ      + Q++ +L  T+ +    +P       ISST+
Sbjct: 1687 IEEKEGVSRMLKDTQQSVSELQNRCYWLERQVQNQLSPTQGSVYGEVPPGAPQEPISSTV 1746

Query: 1119 EPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTE 1167
              +  D+ ++             L  + EEE  + R  + E++ +L  +
Sbjct: 1747 NQVGSDSRDLRMRLSEAEIHLSQLNSRLEEE--RSRREVAEEALRLTEQ 1793



 Score = 83.4 bits (197), Expect = 5e-14
 Identities = 207/1133 (18%), Positives = 463/1133 (40%), Gaps = 98/1133 (8%)

Query: 143  DVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXX 202
            ++  L + I +KD  +  L   M      I +L++++  K+ ++    +           
Sbjct: 612  EIDRLQDVITDKDKEILALSSSMAEYSEQIHELKQEMKLKEDVLTKVEENVQIFRDPQLS 671

Query: 203  XXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEA 262
                         +Q+ K + +    + E +     +   I+  +     +++    +E 
Sbjct: 672  DQQFFNILIPKLIEQLKKTESDLKVAKKESESRSNEIKDFIKQTEDDKKIIQDLR--MEI 729

Query: 263  ARFEISLEHSKL-AQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANM 321
             + +I+L+  +   +++ +              ++KQ  E     KT IEE+ + +    
Sbjct: 730  QKLQINLKEPQSDGEQVHEKDFLKEERNKLLSEVSKQKSELLRFSKT-IEEQVACQEQLK 788

Query: 322  TELTKKIELLEHLNCQIRQTNKELE------NKLATMGTESKAVSSPSKKGSPLISRKSG 375
             ++  K E++  L  +++   +EL       N   T+  E+K     S     + S KS 
Sbjct: 789  QDIQDKSEVIFSLEQKLKIVQEELVVERDRFNSELTIRDEAKEHLEKSLS-CEIDSVKSV 847

Query: 376  RNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXX 435
            +N   K+K    Q   E  +Q   K++  +   +++  +Q  N  L+   + +   ++  
Sbjct: 848  KNDNQKLKESLEQNLGELASQ---KQLLDSAAIEIQ-ALQDQNSSLI---FQVKSLESDN 900

Query: 436  XXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKD 495
                     +   ++ +  E ++ +   S I +  + E V  I+  Q   K+EL   +++
Sbjct: 901  CHLRVEIETRVQSLSDVSEEKKRLLNKISQIELQLS-ESVKTISDFQRD-KEELY--LRE 956

Query: 496  VNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSK-VSDSN 554
             ++K  +EK K +  +I+   D +   +  +IK     +  L + QK     ++ VSD N
Sbjct: 957  ADLKKELEKNKQSITEISLEKDGVVELHNALIKQNQQLQEILDEKQKEALVLTQAVSDLN 1016

Query: 555  KEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLK 614
             +I    +E   L+ ++  L+E+ G+LQ         R I   + K + E     ET   
Sbjct: 1017 NKITITLKENEKLASQIVSLDEQNGSLQ---------RQINEQM-KSLTETTKERETLQN 1066

Query: 615  AISLLESQKFDLVQELH-ILQQKYD---EVEDKLADISQLQSDQVCSEIKSVHLEEQIDA 670
             I   E+Q  +  + +  +L+ K D   +VE+      +LQ++    + KS    +    
Sbjct: 1067 KIQFFETQDVENHKIIEGLLKAKEDLLLQVEEHKVIEQKLQANAEMLQKKSSECTDLTQG 1126

Query: 671  LSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMN----KLQNYIQENMDLTDKLEK 726
            LS +K+E+  +   L+    ++    K++  +KE I+     +++ Y Q+   L D +  
Sbjct: 1127 LSETKEEVDHLKRKLESSNSEVV-KCKNIMLEKEKILTDQRMQIEAYQQQFKHLQDNISV 1185

Query: 727  MSAEKISELLAKINHEEQSKIQTQFGIDAKIQ-----ERDLYIENIESELSKYKSRICRL 781
            +  +           E+ + +Q +      +Q     ER+L   + + E+S  K    RL
Sbjct: 1186 LQEQAFKHKSGLT--EKDTLLQKESNACVLLQKELGHERELVFTS-QQEISSLKVECSRL 1242

Query: 782  EESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDEL--VNRLAVLMDHDRV--- 836
             +++   E++  +L  K  +  ++L+E  K          +L  +N     ++ D     
Sbjct: 1243 NQAL---EEKENTLREKNLECQNHLEELCKRNETLVSLTSQLGLMNASIAKLESDNANLK 1299

Query: 837  --VEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQ-----QHYNALVEKANRTDLA 889
              +E+ L E     +EL +K QI L E Q+   +++D       +  N++ E   + ++ 
Sbjct: 1300 DTLERHLSESARLKEELMQK-QIELVEYQDSGQAMNDQNSIIKSELKNSMTEMVRQKEMI 1358

Query: 890  ESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEK 949
             S   + +++   L S  ++   EH  L   +   + D E  F TQ       +  L E 
Sbjct: 1359 TSLQNELESKRVKLGSLEEKFKSEHSQLEALQLT-LRDKEDVFQTQEMHVNNMQAKLLES 1417

Query: 950  YEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNL---ELIDKHVQKQQTQSPDYTEQ 1006
              +  + + +L+ + Q  +  +E+ +     +    L   E  +  ++ +   +  +  +
Sbjct: 1418 EGQIKQRILKLQEENQSLRTALEDKDKEFSLVKTTLLAQSEACESRLKSEMVATAQFQRE 1477

Query: 1007 YIN---EINKLNALLKQKDEEIIALNQK---INNAQVSYMSMVSDYESKLAQFTTKLENM 1060
              N   ++N+L +++ +KD  ++   +K   + ++     S VS    ++ Q T++++ +
Sbjct: 1478 IQNLQEKMNQLISIITEKDSLLMQEKEKYMCLQSSASELESTVSQLNCQIKQLTSEIKQL 1537

Query: 1061 EEEMQRVSKQLLDSKQHNEELQILVRE--------QDDQIKELKETKLTFE----MNIPK 1108
             E   +  +    ++   ++L  L +         + + +K L E  L  E    + + K
Sbjct: 1538 RETQTKKEQVTFAAQSQMQKLDELYKNLQQECDLTKQELLKVLNEKSLKEEEVRKLILEK 1597

Query: 1109 TEGMIISS-TIEPMSDDANNVDXXXXXXXXXXXXLKVQE--EEEF--IQERSVLQEQSAK 1163
             + +  SS  I+   D  +N              ++ ++  + EF  +Q +    +Q  +
Sbjct: 1598 EDILRTSSYQIQTTQDQQHNWRSTTMNKVEEVQAMEKKKLHKMEFMALQGKEASSDQWVQ 1657

Query: 1164 LNTELQECYTKIIQ----LETLNTELTGHDVVNQEQINQLKSKLEQLNTENDN 1212
            LN  LQ+C  +I Q    L+ LN +L    +  +E ++++    +Q  +E  N
Sbjct: 1658 LNGHLQQCQLEIQQRECGLQQLNIKLQ-QTIEEKEGVSRMLKDTQQSVSELQN 1709



 Score = 55.6 bits (128), Expect = 1e-05
 Identities = 141/737 (19%), Positives = 300/737 (40%), Gaps = 61/737 (8%)

Query: 98   LKQKEILMEKIKQYKELSKR--SSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKD 155
            LK KE L+ +++++K + ++  ++  +++                  +V HL   ++  +
Sbjct: 1086 LKAKEDLLLQVEEHKVIEQKLQANAEMLQKKSSECTDLTQGLSETKEEVDHLKRKLESSN 1145

Query: 156  NALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTK 215
            + +   +  M   E  + D + +I    Q  + K+                     +DT 
Sbjct: 1146 SEVVKCKNIMLEKEKILTDQRMQIEAYQQ--QFKHLQDNISVLQEQAFKHKSGLTEKDTL 1203

Query: 216  QQMTKMQENFIAMEAEWKDEKQRLL---KDIESKDVRISSLEEANKLLEAARFEISLEHS 272
             Q  K     + ++ E   E++ +    ++I S  V  S L +A +  E    E +LE  
Sbjct: 1204 LQ--KESNACVLLQKELGHERELVFTSQQEISSLKVECSRLNQALEEKENTLREKNLECQ 1261

Query: 273  KLAQEL----EQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTE--LTK 326
               +EL    E               +AK  +E       +  E+   E A + E  + K
Sbjct: 1262 NHLEELCKRNETLVSLTSQLGLMNASIAK--LESDNANLKDTLERHLSESARLKEELMQK 1319

Query: 327  KIELLEH------LNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTAS 380
            +IEL+E+      +N Q      EL+N +  M  + + ++S   +      R    +   
Sbjct: 1320 QIELVEYQDSGQAMNDQNSIIKSELKNSMTEMVRQKEMITSLQNELES--KRVKLGSLEE 1377

Query: 381  KMKSPWSQLSSETLN-QDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVIS--EKDTXXXX 437
            K KS  SQL +  L  +D +      E+    M  + L  +   K+ ++   E++     
Sbjct: 1378 KFKSEHSQLEALQLTLRDKEDVFQTQEMHVNNMQAKLLESEGQIKQRILKLQEENQSLRT 1437

Query: 438  XXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEI-KDV 496
                   + +L+    L   +  E      +    +   EI  +QE++ Q ++    KD 
Sbjct: 1438 ALEDKDKEFSLVKTTLLAQSEACESRLKSEMVATAQFQREIQNLQEKMNQLISIITEKDS 1497

Query: 497  NVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKE 556
             +    EK    +   ++L   +   N  + ++ S    ++KQ+++T     +V+ + + 
Sbjct: 1498 LLMQEKEKYMCLQSSASELESTVSQLNCQIKQLTS----EIKQLRETQTKKEQVTFAAQS 1553

Query: 557  IVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAI 616
             ++  +EL+   Q+  +L +++    L +++  S  + E +V K ++E E++  T    I
Sbjct: 1554 QMQKLDELYKNLQQECDLTKQE---LLKVLNEKS--LKEEEVRKLILEKEDILRTSSYQI 1608

Query: 617  SLLESQK-------FDLVQELHILQQK-YDEVEDKLADISQLQSDQVCSEIKSVHLEEQI 668
               + Q+        + V+E+  +++K   ++E       +  SDQ      + HL++  
Sbjct: 1609 QTTQDQQHNWRSTTMNKVEEVQAMEKKKLHKMEFMALQGKEASSDQWVQ--LNGHLQQC- 1665

Query: 669  DALSASKKELALVIENLKLDK--EQLYGTIKDLENDKEDIMNKLQN--YIQENMDLTDKL 724
              L   ++E  L   N+KL +  E+  G  + L++ ++ + ++LQN  Y  E   + ++L
Sbjct: 1666 -QLEIQQRECGLQQLNIKLQQTIEEKEGVSRMLKDTQQSV-SELQNRCYWLERQ-VQNQL 1722

Query: 725  EKMSAEKISELLAKINHEEQSKIQTQFGIDAK-----IQERDLYIENIESELSKYKSRIC 779
                     E+      E  S    Q G D++     + E ++++  + S L + +SR  
Sbjct: 1723 SPTQGSVYGEVPPGAPQEPISSTVNQVGSDSRDLRMRLSEAEIHLSQLNSRLEEERSRRE 1782

Query: 780  RLEESIAVMEDRRYSLE 796
              EE++ + E R  S+E
Sbjct: 1783 VAEEALRLTEQRVVSME 1799


>UniRef50_UPI00006CFFCF Cluster: hypothetical protein TTHERM_00755860;
            n=1; Tetrahymena thermophila SB210|Rep: hypothetical
            protein TTHERM_00755860 - Tetrahymena thermophila SB210
          Length = 1211

 Score =  138 bits (334), Expect = 1e-30
 Identities = 187/1001 (18%), Positives = 441/1001 (44%), Gaps = 88/1001 (8%)

Query: 375  GRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTX 434
            G       +SP + + S+   Q   +  N+  I    +++Q +++     + +I E D  
Sbjct: 192  GNKNVQNFESPNNNMESQ---QQQQQSYNEKNIKGDYVLMQKISEQQKQIQTLIDENDGL 248

Query: 435  XXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIK 494
                      K++L  +L++  ++ ++    IH     + + +  K  E+    +  +  
Sbjct: 249  TRITQLLSEEKNSLKDELKILKEERIQVIHKIHEDDKIQRLKQRVKELEENNLYVRKQFS 308

Query: 495  DVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKV----KSNHKLKLKQMQKTIDNFSKV 550
            ++ + +L+EK  + +     + D  +A ++ +I +    +  +K ++K+++K I  +   
Sbjct: 309  ELEI-NLLEKEATIKTYQETIQDRSEANSEKLINIYIENEEKYKKRIKELEKEIKKYENT 367

Query: 551  SDSNKEIVRLTEELHHLSQK---VAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMEN 607
                ++  ++ E+     QK   + +L+  + N +L L + ++    E   Y K I+ E 
Sbjct: 368  FQ--EQTAKMNEQQIKFQQKDLSIQQLQSNQMNEKLKLQEENN----ELRKYIKQIQEEQ 421

Query: 608  LAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQS--DQVCSEIKSVHLE 665
                ++KA ++ ++++    +  + ++Q   +++     ++ LQ   D    E K+V  E
Sbjct: 422  ----QIKAFNVSQNEQECQKELKNHIEQLNKQIQLYTEQLNNLQDNYDLKAEEYKNVLYE 477

Query: 666  EQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLE 725
               D  S   +EL + I  LK DK+ +   +K + N+ + + N LQ    E      +L 
Sbjct: 478  S--DKKSKEIRELNIQIAQLKKDKDDILEKLKIMMNENDKLSNILQQKDSEQHANQQRLL 535

Query: 726  KMSA--EKISELLAKINHEE-------QSKIQTQFGIDAKIQERDLYIENIESELSKYKS 776
            ++     K+SE L KIN+ E       Q K Q Q  +  K +  ++ ++ IE  L + ++
Sbjct: 536  QIDGLKSKLSEQLDKINNLEKIVKEFDQFKKQ-QIIVVEKNENLNIQLQTIEKNLQEKQN 594

Query: 777  RICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRV 836
             I +L ES++   +      +  D+  S +++ ++   + + + +++ + L      + +
Sbjct: 595  EIQKLNESLSEKNEIILEKAKINDEKISCIRQNEQQLIQISEKLNQVSSSLEATTKQNEL 654

Query: 837  VEKQLLEIEHENKELQKKNQILLEENQN-------LQISLSDMQQHYNALVEKANRTDLA 889
            +++Q+ + + E + LQ++ Q   E+ Q        L++ + ++ Q         ++ ++ 
Sbjct: 655  LQQQIAQQKKETELLQEQIQFQAEQIQQQKQQKKELELKIVNLDQELTDKKLLISQDEIQ 714

Query: 890  ESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEK 949
             +E++    +L +   + +    + + +I +  + I+ L+            +   L E 
Sbjct: 715  ANEASSRIDKLSEALKSAEEDLRQKEIIIQELSQSIDQLQGVMKQVANDQNLEISNLKES 774

Query: 950  YEKNIEYVTQLEAQLQ-EYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYI 1008
            ++K I+Y+  L AQL+ EY   IE  NM +  L+   ++   K V +   ++ +  +Q  
Sbjct: 775  HQKEIQYLQALNAQLEKEYLKKIEEKNMKINSLDD-RIKFYKKEVSQLNEEAKENEQQIQ 833

Query: 1009 ---NEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQ 1065
               +EI+ L   +     +I  + + +N +++   ++     +   Q        +++ Q
Sbjct: 834  MKNSEISNLKVNISDLSSQISNIAKHLNESKLCEETLQEKVINYTTQINEYKSEQQQQQQ 893

Query: 1066 RVSKQLLDSKQH-NEELQILVREQDDQIKELKETKLTFEMNIPKTE--GMIISSTIEPMS 1122
             +SK  +    H N E Q+ V E+  +IKEL+  ++T    I + E  G+  +  I+ + 
Sbjct: 894  LISKLSISYDFHSNLEKQLSVFEE--KIKELERERVTLNTKISEHESNGIETNQKIKILE 951

Query: 1123 D----------DANNVDXXXXXXXXXXXXLK-----VQEEEEFIQERSVLQEQSAKLNTE 1167
            D          D  N              L      ++   EF++++    E + +L TE
Sbjct: 952  DKLQFTENSYKDLQNQKSQDLEKHQNIANLSEGFQFIKSTYEFLKDKEQADE-NLRL-TE 1009

Query: 1168 LQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSA 1227
             +    K+ + E  N++L   D + ++ +NQ++ +L+ +NT+ D  +        ++  A
Sbjct: 1010 QELIKHKLKEYEIQNSQL---DALVKQYMNQIE-QLKSVNTQKDQEIQEYKRKMMNLQDA 1065

Query: 1228 VDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIV 1287
            ++      + L ++ + + E D  K E       S  ++K  +    +     E T   +
Sbjct: 1066 LN------SNLIEKSIIEEELDSIKEEK------SDLKTKMNECQLQISQIKNEST---L 1110

Query: 1288 TMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIE 1328
            T E++ ++Q  L  ++E  +NLQ+K  +   Q+    ++++
Sbjct: 1111 TAEEMKNIQQNLTLRKESNQNLQKKLLETSQQLAFALNQLQ 1151



 Score =  117 bits (281), Expect = 3e-24
 Identities = 160/829 (19%), Positives = 361/829 (43%), Gaps = 79/829 (9%)

Query: 807  QEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQ 866
            Q++Q++Y+E  I+ D       VLM      +KQ+  +  EN  L +  Q+L EE  +L+
Sbjct: 210  QQQQQSYNEKNIKGDY------VLMQKISEQQKQIQTLIDENDGLTRITQLLSEEKNSLK 263

Query: 867  ISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQ-KKKEI 925
              L  +++    ++ K +  D  +    + + ++++LE N   +  +   L +   +KE 
Sbjct: 264  DELKILKEERIQVIHKIHEDDKIQ----RLKQRVKELEENNLYVRKQFSELEINLLEKEA 319

Query: 926  EDLEIEFNTQIESAIRDKKVLN---EKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELN 982
                 +   Q  S    +K++N   E  EK  + + +LE ++++Y+N  +       ++N
Sbjct: 320  TIKTYQETIQDRSEANSEKLINIYIENEEKYKKRIKELEKEIKKYENTFQE---QTAKMN 376

Query: 983  KMNLELIDKHVQKQQTQSPDYTE--QYINEINKLNALLK--QKDEEIIALN--QKINNAQ 1036
            +  ++   K +  QQ QS    E  +   E N+L   +K  Q++++I A N  Q     Q
Sbjct: 377  EQQIKFQQKDLSIQQLQSNQMNEKLKLQEENNELRKYIKQIQEEQQIKAFNVSQNEQECQ 436

Query: 1037 VSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELK 1096
                + +     ++  +T +L N+++     +++  +    +++    +RE + QI +LK
Sbjct: 437  KELKNHIEQLNKQIQLYTEQLNNLQDNYDLKAEEYKNVLYESDKKSKEIRELNIQIAQLK 496

Query: 1097 ETK--LTFEMNIPKTEGMIISSTIEPMSDD--AN-----NVDXXXXXXXXXXXXLK---- 1143
            + K  +  ++ I   E   +S+ ++    +  AN      +D            +     
Sbjct: 497  KDKDDILEKLKIMMNENDKLSNILQQKDSEQHANQQRLLQIDGLKSKLSEQLDKINNLEK 556

Query: 1144 -VQEEEEFIQERSVLQEQSAKLNTELQ----ECYTKIIQLETLNTELTGHDVVNQEQINQ 1198
             V+E ++F +++ ++ E++  LN +LQ        K  +++ LN  L+  + +  E+   
Sbjct: 557  IVKEFDQFKKQQIIVVEKNENLNIQLQTIEKNLQEKQNEIQKLNESLSEKNEIILEKAKI 616

Query: 1199 LKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELR 1258
               K+  +  +N+  L  ++E  + +SS+++    +  EL +Q +AQ++ + +  + +++
Sbjct: 617  NDEKISCIR-QNEQQLIQISEKLNQVSSSLEATTKQ-NELLQQQIAQQKKETELLQEQIQ 674

Query: 1259 VQLSAFESKYEQLLD---SVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYAD 1315
             Q    + + +Q  +    + +  QE T+K + + Q     N+   + + L    +   +
Sbjct: 675  FQAEQIQQQKQQKKELELKIVNLDQELTDKKLLISQDEIQANEASSRIDKLSEALKSAEE 734

Query: 1316 VINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENA 1375
             + Q EI+  E+                       +L+  +Q  K++Q    LN   E  
Sbjct: 735  DLRQKEIIIQELSQSIDQLQGVMKQVANDQNLEISNLKESHQ--KEIQYLQALNAQLEKE 792

Query: 1376 QLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYT---ITLTQRND 1432
             LKK              R+   + +V +L  + +  + +I  K  E +   + ++  + 
Sbjct: 793  YLKKIE-EKNMKINSLDDRIKFYKKEVSQLNEEAKENEQQIQMKNSEISNLKVNISDLSS 851

Query: 1433 EFENV--------------RQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQK 1478
            +  N+              +++++ Y  +I +   E++ +  ++  K+  + + +  ++K
Sbjct: 852  QISNIAKHLNESKLCEETLQEKVINYTTQINEYKSEQQQQQQLIS-KLSISYDFHSNLEK 910

Query: 1479 ESEI--ERVKLIEE----LNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIE 1532
            +  +  E++K +E     LN KI+E  S   +  +  K LE+++  T      L+NQ+ +
Sbjct: 911  QLSVFEEKIKELERERVTLNTKISEHESNGIETNQKIKILEDKLQFTENSYKDLQNQKSQ 970

Query: 1533 IVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELL 1581
             +  +  I NL          I+    F  D +Q  DE L  T  +EL+
Sbjct: 971  DLEKHQNIANLSE----GFQFIKSTYEFLKDKEQA-DENLRLT-EQELI 1013



 Score =  102 bits (245), Expect = 7e-20
 Identities = 214/1046 (20%), Positives = 463/1046 (44%), Gaps = 118/1046 (11%)

Query: 476  NEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAE--EQITQLNDE--IDAANKNMIKVKS 531
            N++   ++ L QE N ++    ++     LK  +     T L+D       NKN+   +S
Sbjct: 143  NQVTTNEQNLAQE-NQQVAYQQIRLSASALKQLKYNNSPTVLSDYNYSGLGNKNVQNFES 201

Query: 532  -NHKLKLKQMQKTIDN----------FSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGN 580
             N+ ++ +Q Q+   N            K+S+  K+I  L +E   L++    L EEK +
Sbjct: 202  PNNNMESQQQQQQSYNEKNIKGDYVLMQKISEQQKQIQTLIDENDGLTRITQLLSEEKNS 261

Query: 581  L--QLHLVDYDSGRMI----ESDVYKKMIE-MENLAETRLKAISLLESQKFDLVQELHIL 633
            L  +L ++  +  ++I    E D  +++ + ++ L E  L         + +L+++   +
Sbjct: 262  LKDELKILKEERIQVIHKIHEDDKIQRLKQRVKELEENNLYVRKQFSELEINLLEKEATI 321

Query: 634  QQKYDEVEDKL-ADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQL 692
            +   + ++D+  A+  +L +  + +E K     ++++     K E     +  K++++Q+
Sbjct: 322  KTYQETIQDRSEANSEKLINIYIENEEKYKKRIKELEK-EIKKYENTFQEQTAKMNEQQI 380

Query: 693  YGTIKDLE---------NDK---EDIMNKLQNY---IQENMDL----TDKLEKMSAEKIS 733
                KDL          N+K   ++  N+L+ Y   IQE   +      + E+   +++ 
Sbjct: 381  KFQQKDLSIQQLQSNQMNEKLKLQEENNELRKYIKQIQEEQQIKAFNVSQNEQECQKELK 440

Query: 734  ELLAKINH------EEQSKIQTQFGIDAKIQERDLYIENIES-ELSKYKSRICRLEESIA 786
              + ++N       E+ + +Q  + + A+  +  LY  + +S E+ +   +I +L++   
Sbjct: 441  NHIEQLNKQIQLYTEQLNNLQDNYDLKAEEYKNVLYESDKKSKEIRELNIQIAQLKKDKD 500

Query: 787  VMEDRRYSLERKADQLGSYLQEK---QKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLE 843
             + ++   +  + D+L + LQ+K   Q A  +  +Q D L ++L+  +D    +EK + E
Sbjct: 501  DILEKLKIMMNENDKLSNILQQKDSEQHANQQRLLQIDGLKSKLSEQLDKINNLEKIVKE 560

Query: 844  IEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTD-LAESESTKYQTQLRD 902
             +    + +K+  I++E+N+NL I L  ++++   L EK N    L ES S K +  L  
Sbjct: 561  FD----QFKKQQIIVVEKNENLNIQLQTIEKN---LQEKQNEIQKLNESLSEKNEIILEK 613

Query: 903  LESNLKRIT----HEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVT 958
             + N ++I+    +E Q + + +K       +E  T+    ++ +    +K  + ++   
Sbjct: 614  AKINDEKISCIRQNEQQLIQISEKLNQVSSSLEATTKQNELLQQQIAQQKKETELLQEQI 673

Query: 959  QLEA-QLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNAL 1017
            Q +A Q+Q+ K   + L + +  L++   EL DK +   Q +      +  + I+KL+  
Sbjct: 674  QFQAEQIQQQKQQKKELELKIVNLDQ---ELTDKKLLISQDEI--QANEASSRIDKLSEA 728

Query: 1018 LKQKDE-----EII--ALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQ 1070
            LK  +E     EII   L+Q I+  Q     + +D   +++      +   + +Q ++ Q
Sbjct: 729  LKSAEEDLRQKEIIIQELSQSIDQLQGVMKQVANDQNLEISNLKESHQKEIQYLQALNAQ 788

Query: 1071 L-LDSKQHNEELQILVREQDDQIKELKE--TKLTFEMNIPKTEGMIISSTIEPMSDDANN 1127
            L  +  +  EE  + +   DD+IK  K+  ++L  E    + +  + +S I  +  + ++
Sbjct: 789  LEKEYLKKIEEKNMKINSLDDRIKFYKKEVSQLNEEAKENEQQIQMKNSEISNLKVNISD 848

Query: 1128 VDXXXXXXXXXXXXLKVQEE---EEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTE 1184
            +              K+ EE   E+ I   + + E  ++   + Q+  +K+      ++ 
Sbjct: 849  LSSQISNIAKHLNESKLCEETLQEKVINYTTQINEYKSE-QQQQQQLISKLSISYDFHSN 907

Query: 1185 LTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLA 1244
            L     V +E+I +L+ +   LNT+     S   E    I    D+  F     +K    
Sbjct: 908  LEKQLSVFEEKIKELERERVTLNTKISEHESNGIETNQKIKILEDKLQF-TENSYKDLQN 966

Query: 1245 QREADFQKTEH--ELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDK 1302
            Q+  D +K ++   L       +S YE L D  Q+    + N  +T +++  +++KL++ 
Sbjct: 967  QKSQDLEKHQNIANLSEGFQFIKSTYEFLKDKEQA----DENLRLTEQEL--IKHKLKEY 1020

Query: 1303 EEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQM 1362
            E     L       +NQIE L+S +  +K                   D    N   K +
Sbjct: 1021 EIQNSQLDALVKQYMNQIEQLKS-VNTQK----DQEIQEYKRKMMNLQDALNSNLIEKSI 1075

Query: 1363 QEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHE 1422
             E+ + +I EE + LK               ++N+ + ++ ++ ++  L   E+  K  +
Sbjct: 1076 IEEELDSIKEEKSDLK--------------TKMNECQLQISQIKNESTLTAEEM--KNIQ 1119

Query: 1423 YTITLTQRNDEFENVRQQLVEYEKRI 1448
              +TL  R +  +N++++L+E  +++
Sbjct: 1120 QNLTL--RKESNQNLQKKLLETSQQL 1143



 Score = 96.7 bits (230), Expect = 5e-18
 Identities = 178/892 (19%), Positives = 376/892 (42%), Gaps = 66/892 (7%)

Query: 217  QMTKMQENFIAMEAE-WKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLA 275
            Q+   ++N +  E +  K+E+ +++  I   D +I  L++  K LE     +  + S+L 
Sbjct: 253  QLLSEEKNSLKDELKILKEERIQVIHKIHEDD-KIQRLKQRVKELEENNLYVRKQFSELE 311

Query: 276  QELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLN 335
              L +               ++ + E       E EEK    I  + +  KK E     N
Sbjct: 312  INLLEKEATIKTYQETIQDRSEANSEKLINIYIENEEKYKKRIKELEKEIKKYE-----N 366

Query: 336  CQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASK-MKSPWSQLSSETL 394
                QT K  E ++     +       S + +  +  +   N   K +K    +   +  
Sbjct: 367  TFQEQTAKMNEQQIKFQQKDLSIQQLQSNQMNEKLKLQEENNELRKYIKQIQEEQQIKAF 426

Query: 395  N-----QDTDKKINKNEIAKLEMVIQSLNKDL--VDKEYVISEKDTXXXXXXXXXXGKDT 447
            N     Q+  K++ KN I +L   IQ   + L  +   Y +  ++            K+ 
Sbjct: 427  NVSQNEQECQKEL-KNHIEQLNKQIQLYTEQLNNLQDNYDLKAEEYKNVLYESDKKSKEI 485

Query: 448  LIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELN-DEIKDVNVKDLIEKLK 506
                +Q+   +  +   L  +     + ++++ + +Q   E + ++ + + +  L  KL 
Sbjct: 486  RELNIQIAQLKKDKDDILEKLKIMMNENDKLSNILQQKDSEQHANQQRLLQIDGLKSKLS 545

Query: 507  SAEEQITQLND---EIDAANKN-MIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTE 562
               ++I  L     E D   K  +I V+ N  L + Q+Q TI+    + +   EI +L E
Sbjct: 546  EQLDKINNLEKIVKEFDQFKKQQIIVVEKNENLNI-QLQ-TIEK--NLQEKQNEIQKLNE 601

Query: 563  ELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQ 622
             L   ++ + E + +  + ++  +  +  ++I+  + +K+ ++ +  E   K   LL+ Q
Sbjct: 602  SLSEKNEIILE-KAKINDEKISCIRQNEQQLIQ--ISEKLNQVSSSLEATTKQNELLQQQ 658

Query: 623  KFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQID--ALSASKKELAL 680
                 +E  +LQ+   +++ +   I Q +  +   E+K V+L++++    L  S+ E+  
Sbjct: 659  IAQQKKETELLQE---QIQFQAEQIQQQKQQKKELELKIVNLDQELTDKKLLISQDEIQA 715

Query: 681  VIENLKLDK--EQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAK 738
               + ++DK  E L    +DL   KE I+ +L   I +   +  ++      +IS L  K
Sbjct: 716  NEASSRIDKLSEALKSAEEDLRQ-KEIIIQELSQSIDQLQGVMKQVANDQNLEISNL--K 772

Query: 739  INHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERK 798
             +H  Q +IQ    ++A++++   Y++ IE +  K  S    L++ I   +     L  +
Sbjct: 773  ESH--QKEIQYLQALNAQLEKE--YLKKIEEKNMKINS----LDDRIKFYKKEVSQLNEE 824

Query: 799  ADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQI- 857
            A +    +Q K    S   +   +L ++++ +  H  + E +L E   + K +    QI 
Sbjct: 825  AKENEQQIQMKNSEISNLKVNISDLSSQISNIAKH--LNESKLCEETLQEKVINYTTQIN 882

Query: 858  -LLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQT 916
                E Q  Q  +S +   Y+       +  + E +  + + +   L  N K   HE   
Sbjct: 883  EYKSEQQQQQQLISKLSISYDFHSNLEKQLSVFEEKIKELERERVTL--NTKISEHESNG 940

Query: 917  LIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNI-------EYVTQLEAQLQEYKN 969
            +   +K +I + +++F       ++++K  + +  +NI       +++      L++ + 
Sbjct: 941  IETNQKIKILEDKLQFTENSYKDLQNQKSQDLEKHQNIANLSEGFQFIKSTYEFLKDKEQ 1000

Query: 970  NIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALN 1029
              ENL +  +EL K  L    K  + Q +Q     +QY+N+I +L ++  QKD+EI    
Sbjct: 1001 ADENLRLTEQELIKHKL----KEYEIQNSQLDALVKQYMNQIEQLKSVNTQKDQEIQEYK 1056

Query: 1030 QKINNAQVSYMSMV---SDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHN 1078
            +K+ N Q +  S +   S  E +L     +  +++ +M     Q+   K  +
Sbjct: 1057 RKMMNLQDALNSNLIEKSIIEEELDSIKEEKSDLKTKMNECQLQISQIKNES 1108



 Score = 67.3 bits (157), Expect = 3e-09
 Identities = 132/664 (19%), Positives = 293/664 (44%), Gaps = 79/664 (11%)

Query: 298  QSIEPSCEEK-TEIEEKG-SLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTE 355
            Q+IE + +EK  EI++   SL   N   L K     E ++C IRQ  ++L      +   
Sbjct: 583  QTIEKNLQEKQNEIQKLNESLSEKNEIILEKAKINDEKISC-IRQNEQQLIQISEKLNQV 641

Query: 356  SKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQ 415
            S ++ + +K+   L  + + +   +++     Q  +E + Q   +K       +LE+ I 
Sbjct: 642  SSSLEATTKQNELLQQQIAQQKKETELLQEQIQFQAEQIQQQKQQK------KELELKIV 695

Query: 416  SLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDV 475
            +L+++L DK+ +IS+ +             D L   L+   +   +   +I      E  
Sbjct: 696  NLDQELTDKKLLISQDEIQANEASSRI---DKLSEALKSAEEDLRQKEIIIQ-----ELS 747

Query: 476  NEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKL 535
              I ++Q  +KQ  ND+  ++ + +L E  +   + +  LN +++      I+ K N K+
Sbjct: 748  QSIDQLQGVMKQVANDQ--NLEISNLKESHQKEIQYLQALNAQLEKEYLKKIEEK-NMKI 804

Query: 536  -----KLKQMQKTIDNFSKVSDSNKEIVRL-TEELHHLSQKVAELEEEKGNLQLHLVDYD 589
                 ++K  +K +   ++ +  N++ +++   E+ +L   +++L  +  N+  HL   +
Sbjct: 805  NSLDDRIKFYKKEVSQLNEEAKENEQQIQMKNSEISNLKVNISDLSSQISNIAKHL---N 861

Query: 590  SGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLA---- 645
              ++ E  + +K+I       T++      + Q+  L+ +L I    +  +E +L+    
Sbjct: 862  ESKLCEETLQEKVINYT----TQINEYKSEQQQQQQLISKLSISYDFHSNLEKQLSVFEE 917

Query: 646  DISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKED 705
             I +L+ ++V    K    E + + +  ++K    ++E+     E  Y   KDL+N K  
Sbjct: 918  KIKELERERVTLNTKIS--EHESNGIETNQK--IKILEDKLQFTENSY---KDLQNQKSQ 970

Query: 706  IMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIE 765
             + K QN    N+    +  K + E + +   K   +E  ++  Q  I  K++E ++   
Sbjct: 971  DLEKHQNIA--NLSEGFQFIKSTYEFLKD---KEQADENLRLTEQELIKHKLKEYEIQNS 1025

Query: 766  NIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVN 825
             +++ + +Y ++I                     +QL S   +K +   EY  +   L +
Sbjct: 1026 QLDALVKQYMNQI---------------------EQLKSVNTQKDQEIQEYKRKMMNLQD 1064

Query: 826  RLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQ-NLQISLSDMQQHYNALVEKAN 884
             L     +  ++EK ++E E ++ + ++K+ +  + N+  LQIS    +    A   K  
Sbjct: 1065 AL-----NSNLIEKSIIEEELDSIK-EEKSDLKTKMNECQLQISQIKNESTLTAEEMKNI 1118

Query: 885  RTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLE-IEFNTQIESAIRDK 943
            + +L   + +    Q + LE++ +     +Q   +QK +    ++ +E N+Q E    D 
Sbjct: 1119 QQNLTLRKESNQNLQKKLLETSQQLAFALNQLQQIQKSRYQSPIKSVEENSQ-EQGFPDN 1177

Query: 944  KVLN 947
            ++++
Sbjct: 1178 QIIS 1181



 Score = 50.0 bits (114), Expect = 5e-04
 Identities = 113/611 (18%), Positives = 255/611 (41%), Gaps = 67/611 (10%)

Query: 154  KDNALSVLQVKMKIME-TTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXE 212
            + N   ++Q+  K+ + ++ L+   K NE  Q   A+ K  T                 +
Sbjct: 625  RQNEQQLIQISEKLNQVSSSLEATTKQNELLQQQIAQQKKETELLQEQIQFQAEQI---Q 681

Query: 213  DTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHS 272
              KQQ  +++   + ++ E  D+K  + +D    +   S +++ ++ L++A  ++  +  
Sbjct: 682  QQKQQKKELELKIVNLDQELTDKKLLISQDEIQANEASSRIDKLSEALKSAEEDLR-QKE 740

Query: 273  KLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTEL-TKKIELL 331
             + QEL                   QSI+       ++    +LEI+N+ E   K+I+ L
Sbjct: 741  IIIQEL------------------SQSIDQLQGVMKQVANDQNLEISNLKESHQKEIQYL 782

Query: 332  EHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSS 391
            + LN Q+    KE   K+     E K     + K + L  R          K   SQL+ 
Sbjct: 783  QALNAQL---EKEYLKKI-----EEK-----NMKINSLDDR------IKFYKKEVSQLNE 823

Query: 392  ETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQ 451
            E    +   ++  +EI+ L++ I  L+  + +    ++E                T I +
Sbjct: 824  EAKENEQQIQMKNSEISNLKVNISDLSSQISNIAKHLNESKLCEETLQEKVINYTTQINE 883

Query: 452  LQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQ 511
             + E QQ  +  S + +  +       + +++QL       + +  +K+L        E+
Sbjct: 884  YKSEQQQQQQLISKLSISYDFH-----SNLEKQL------SVFEEKIKEL------ERER 926

Query: 512  ITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKV 571
            +T LN +I     N I+     K+   ++Q T +++  + +   + +   + + +LS+  
Sbjct: 927  VT-LNTKISEHESNGIETNQKIKILEDKLQFTENSYKDLQNQKSQDLEKHQNIANLSEGF 985

Query: 572  AELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQEL- 630
              ++     L+      ++ R+ E ++ K  ++   +  ++L A   L  Q  + +++L 
Sbjct: 986  QFIKSTYEFLKDKEQADENLRLTEQELIKHKLKEYEIQNSQLDA---LVKQYMNQIEQLK 1042

Query: 631  HILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKE 690
             +  QK  E+++    +  LQ     + I+   +EE++D++   K +L   +   +L   
Sbjct: 1043 SVNTQKDQEIQEYKRKMMNLQDALNSNLIEKSIIEEELDSIKEEKSDLKTKMNECQLQIS 1102

Query: 691  QLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQ 750
            Q+         + ++I   L    + N +L  KL + S ++++  L ++   ++S+ Q+ 
Sbjct: 1103 QIKNESTLTAEEMKNIQQNLTLRKESNQNLQKKLLETS-QQLAFALNQLQQIQKSRYQSP 1161

Query: 751  F-GIDAKIQER 760
               ++   QE+
Sbjct: 1162 IKSVEENSQEQ 1172


>UniRef50_Q22W02 Cluster: Putative uncharacterized protein; n=1;
            Tetrahymena thermophila SB210|Rep: Putative
            uncharacterized protein - Tetrahymena thermophila SB210
          Length = 2101

 Score =  138 bits (333), Expect = 2e-30
 Identities = 264/1347 (19%), Positives = 585/1347 (43%), Gaps = 124/1347 (9%)

Query: 321  MTELTKKIELLEHLNCQ-IRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTA 379
            M +L ++I+LL+++  Q I     +L         ++   S   +K S   S K+G +  
Sbjct: 393  MQKLQEEIQLLQNICVQMINMRIAQLHPFSRDSRKQTLQDSKQLEKDSD--SNKNGNDKR 450

Query: 380  SKMKSPWSQLSSETLNQDTDK--KINKNEIAKLEMVIQSLNKDLVDKEYVISE---KDTX 434
            S         SSE    +  +  KIN++   K++   Q+   DL + E VIS+       
Sbjct: 451  SYSVDGDLYESSEAAQNNLKQQLKINQSFDKKVQQDKQNFVNDLSEAEGVISDILSMSQI 510

Query: 435  XXXXXXXXXGKDTLIAQLQ--LEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDE 492
                      KD    Q Q   +  Q+++  +L  +    +D+ +  K    + Q++N+ 
Sbjct: 511  SSTNYNKNFQKDGQQQQYQDYFKKNQNVD-QTLDELSEIQQDIKDSQKAL--MSQDINES 567

Query: 493  IKD--VNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKV 550
            I+   VN++++ E LK   E++  L +     N+ + K+ +    +  + ++ +    K 
Sbjct: 568  IQSYSVNIQEVQEILKDCSEKLKYLKESNMLNNQQIAKILNQVFYQFLKQEEFLSQQEKE 627

Query: 551  SDSNKEIVRLTE-ELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLA 609
            +   K+I  L   E   +  +   + +E   LQL       G  I+          + + 
Sbjct: 628  NSDEKQIRSLPNLENQSMDNQAEAIIKEHNLLQLESCCQIQGLKIDDISPFSQRFYQEIL 687

Query: 610  ETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQID 669
            E     +   + Q+   + +    Q +  + +  +      Q+D    ++ ++ +EE+I 
Sbjct: 688  EKHKSELEQNQKQEIQNLLDKQDQQNRLYQPQQDIRKDEMNQNDISDDKVNTIKMEEEIQ 747

Query: 670  ALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSA 729
                 +++    + + +L++ +L      +++DK+  + K+Q  IQ+   + ++LE +  
Sbjct: 748  KQVRIREKEIDKMYSAQLEEYKL-----QVQDDKQKELEKIQ--IQQKKQI-EQLENIIK 799

Query: 730  EKISE-LLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVM 788
            E+ +   + +    E+  I+ Q  I+ + +E+ + I+N++ E   +K ++  L + I  +
Sbjct: 800  EQNNNHQIIQNKFIEEQNIKQQLEINLR-EEKQIAIQNLKEE---HKLQMENLMKHINCL 855

Query: 789  -EDRRYSLERKADQ-LGSYLQ---EKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLE 843
             ++ + + E+  +Q L S  Q   EK K  ++ ++ E +    +      ++V+E+  ++
Sbjct: 856  NQELKINQEKVKEQILHSEKQVNLEKDKLKNQESLIEQQQNQNILQQQKINQVIEEYKIQ 915

Query: 844  IEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEK-ANRTDLAESESTKYQTQLRD 902
            +    KEL+ + QI  ++   L+I L + Q +Y    E+  ++T+    ++   Q +   
Sbjct: 916  LNQLRKELESQ-QIQYDK---LKIELQNEQTNYLRQTEQFKSKTEELNQKNKNLQIEFEQ 971

Query: 903  LESNLKRITHE-HQTLIVQKKKEIEDLE-IEFNTQIESAIRDKKVLNEKYEKNIEY-VTQ 959
               N + I  + HQ     +K   +DLE IEF  Q    I   K +NEK +  ++  V Q
Sbjct: 972  ELQNQRNIQQKLHQENEKLQKINSQDLENIEFLNQ---EINQLKEINEKNQNELKSEVKQ 1028

Query: 960  LEAQLQEYKNNIENLNMNV----EELNKMNLELIDKHVQKQQTQ-SPDYTEQYINEINKL 1014
               + Q  + N+  L  N     E++N++  E+ D +++   ++   +  ++ IN I + 
Sbjct: 1029 YSHRCQSLQQNLIELQNNESLYNEKINQLQQEIDDLNMKANSSKLQEEQLKEQINLIKQK 1088

Query: 1015 NALLKQKDEEIIALNQ----KINNAQVSYMSMVS--------DYESKLAQFTTKLENM-- 1060
             + L+Q+ +++   NQ    KI N Q + +  +         + E K+    T+ E++  
Sbjct: 1089 YSKLQQEFDQLKQFNQQQKEKIENLQRTAVEQIQIIQRLKEQECEQKIKDIITEKEDLMK 1148

Query: 1061 ------EEEMQRVSK----QLLDSKQHN--EELQILVREQDDQIKELKETKLTFEMNIPK 1108
                   +E+Q+ +K    +LL+ +++N  +E+Q +++E D QI+ +++ K+  E N   
Sbjct: 1149 QTVEITSKEIQKKNKLEIEKLLEQQENNKQQEIQKILKEHDQQIRSVQQ-KIE-EQN--- 1203

Query: 1109 TEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTEL 1168
             E +I    ++      +               + +QE+E+       L+ Q+ KLN E+
Sbjct: 1204 KEDLITKQKLQSELSKCSEFQKEIFIKDQKIASV-IQEKEQLSLSIKKLEIQNQKLNDEI 1262

Query: 1169 -QECYTKIIQLETL----NTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSS 1223
             Q+  T+  + E L    N  +   +++N++   +++  +E L  +  N+ + + E    
Sbjct: 1263 IQQKQTQKHENEELRQNTNNRINELEILNKDLNKKIQDFVEILKDKEQNINNLIKEKEIE 1322

Query: 1224 ISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESK---YEQLLDSV-QSST 1279
            I   +D    +   + KQ   Q  A  Q+    ++ QLS  +S+    +Q  D++ Q+ T
Sbjct: 1323 IQKNIDFTNCQ--NILKQS-QQENAQLQQQVENIKQQLSQLQSQNALLQQDADNLKQNIT 1379

Query: 1280 QEETNKIVTMEQVTSLQNKL----QDKEEHLR--NLQEKYA-----DVINQ---IEILRS 1325
            +   + +   + + SLQ ++    Q K +HLR  +LQ+K       +++NQ   +  L+S
Sbjct: 1380 KTNKDNLDQKKLIESLQEQIKTADQQKSQHLRQIDLQQKALVQSEKEIVNQKMIVNELKS 1439

Query: 1326 EIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXX 1385
            +I+D++                   D   + +   ++++Q I  +  +N QL+K      
Sbjct: 1440 QIQDQENKKLALLKNEHKTMIDQQNDASNQKKIISELKQQ-ISTLENQNQQLQKQIGEDC 1498

Query: 1386 XXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYE 1445
                     + D   +++E  ++   K  +     +     L Q N         + + +
Sbjct: 1499 TLQSDIIIFLKDKSNQLIETENKFNHKIIDSINTFYTLIEGLIQENKNKIEKLTSIEQKQ 1558

Query: 1446 KRIEDLTYEK--------ESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITE 1497
              +  + Y +        +SE   L+ K+ E +   +  + +     ++   + N++I +
Sbjct: 1559 DNLFSIDYNQLFRKLDTIQSETFKLKKKVIEFSKQIDNQKDQLLDSNIQQAVQKNLQIKD 1618

Query: 1498 SVSLNKQVAELNKALEEEVAKTNEMQTALENQEI--EIVTLND----EITNLQNMVRASS 1551
              S  +++ +L +  EE + K    +   E QE+  +++ L      E+  +QN      
Sbjct: 1619 FKSYFERLQKLVEN-EENLNKKYFKEITDEQQELCLKLMQLQHDIELEVFKIQNQTLEKV 1677

Query: 1552 SKIQKHVSFASDTKQGRDEQLDNTMNK 1578
             K+QK +       Q + E L+  +N+
Sbjct: 1678 DKVQKKIFIGGIPDQSQFENLNQNLNQ 1704



 Score =  111 bits (267), Expect = 2e-22
 Identities = 232/1146 (20%), Positives = 487/1146 (42%), Gaps = 98/1146 (8%)

Query: 475  VNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDE-IDAANKNMIK---VK 530
            +N++   Q+Q +Q    + +  N++   +     ++  +   D  I   ++N+I+     
Sbjct: 209  INKVQNKQKQSQQTFLSKSQQQNLQKNQQMSNQNDQFSSNFQDSPIRIEDQNIIQRHNKN 268

Query: 531  SNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDS 590
             N ++ L+   ++     K+    +  +   +++ HL  K  +L +        L     
Sbjct: 269  KNEQIILQNKDQSQIEAIKLPQDCQIPLEYLKKVQHLIAKYNKLHQNSKLQNTILEQMIQ 328

Query: 591  GRMIESDVYKKMIEMENLAETRLKAISLLESQK-FDLVQELHILQQKYDEVEDKLADISQ 649
             R  +SD   K      L E      +L E +K +  +Q+L  L ++   V DK A + +
Sbjct: 329  QRQPQSDTVSKF-----LFEKYQNGKNLQELEKDYQSIQKLVELLERKILVLDK-AYLKK 382

Query: 650  LQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNK 709
             Q++ V  ++    L+E+I  L    + + + + N+++   QL+   +D          +
Sbjct: 383  RQNE-VQYKLIMQKLQEEIQLL----QNICVQMINMRI--AQLHPFSRDSRKQTLQDSKQ 435

Query: 710  LQNYIQENMDLTDKLEKMSAEKISEL--LAKINHEEQSKIQTQFGIDAKIQERDLYIENI 767
            L+     N +  DK        + E    A+ N ++Q KI   F  D K+Q+      N 
Sbjct: 436  LEKDSDSNKNGNDKRSYSVDGDLYESSEAAQNNLKQQLKINQSF--DKKVQQDKQNFVND 493

Query: 768  ESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQ---KAYSEYTIQEDELV 824
             SE     S I  + +  +   ++ +  + +  Q   Y ++ Q   +   E +  + ++ 
Sbjct: 494  LSEAEGVISDILSMSQISSTNYNKNFQKDGQQQQYQDYFKKNQNVDQTLDELSEIQQDIK 553

Query: 825  NRLAVLMDHD-----RVVEKQLLEIEHENKELQKKNQILLEENQ-NLQISLSDMQQHYNA 878
            +    LM  D     +     + E++   K+  +K + L E N  N Q     + Q +  
Sbjct: 554  DSQKALMSQDINESIQSYSVNIQEVQEILKDCSEKLKYLKESNMLNNQQIAKILNQVFYQ 613

Query: 879  LVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIES 938
             +++       E E++  + Q+R L  NL+  + ++Q   + K+  +  L++E   QI+ 
Sbjct: 614  FLKQEEFLSQQEKENSD-EKQIRSLP-NLENQSMDNQAEAIIKEHNL--LQLESCCQIQG 669

Query: 939  A-IRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQ 997
              I D    ++++ + I    + E + Q  K  I+NL    ++ N++     D  ++K +
Sbjct: 670  LKIDDISPFSQRFYQEILEKHKSELE-QNQKQEIQNLLDKQDQQNRLYQPQQD--IRKDE 726

Query: 998  TQSPDYTEQYINEINKLNALLKQ---KDEEIIALNQKINNAQVS-YMSMVSDYESK---L 1050
                D ++  +N I     + KQ   +++EI     K+ +AQ+  Y   V D + K    
Sbjct: 727  MNQNDISDDKVNTIKMEEEIQKQVRIREKEI----DKMYSAQLEEYKLQVQDDKQKELEK 782

Query: 1051 AQFTTK-----LENMEEEM----QRVSKQLLDSKQHNEELQILVREQDD-QIKELKET-K 1099
             Q   K     LEN+ +E     Q +  + ++ +   ++L+I +RE+    I+ LKE  K
Sbjct: 783  IQIQQKKQIEQLENIIKEQNNNHQIIQNKFIEEQNIKQQLEINLREEKQIAIQNLKEEHK 842

Query: 1100 LTFE-----MNIPKTEGMIISSTI-EPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQE 1153
            L  E     +N    E  I    + E +      V+            ++ Q+ +  +Q+
Sbjct: 843  LQMENLMKHINCLNQELKINQEKVKEQILHSEKQVNLEKDKLKNQESLIEQQQNQNILQQ 902

Query: 1154 RS---VLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTEN 1210
            +    V++E   +LN   +E  ++ IQ + L  EL         Q  Q KSK E+LN +N
Sbjct: 903  QKINQVIEEYKIQLNQLRKELESQQIQYDKLKIELQNEQTNYLRQTEQFKSKTEELNQKN 962

Query: 1211 DNL-LSTVAELRS--SISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESK 1267
             NL +    EL++  +I   + Q   ++ ++  Q L   E         L  +++  +  
Sbjct: 963  KNLQIEFEQELQNQRNIQQKLHQENEKLQKINSQDLENIEF--------LNQEINQLKEI 1014

Query: 1268 YEQLLDSVQSSTQEETNKIVTMEQ-VTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSE 1326
             E+  + ++S  ++ +++  +++Q +  LQN      E +  LQ++  D+   ++   S+
Sbjct: 1015 NEKNQNELKSEVKQYSHRCQSLQQNLIELQNNESLYNEKINQLQQEIDDL--NMKANSSK 1072

Query: 1327 IEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXX 1386
            +++E++                  D   + + + Q Q++ I N+  +   +++       
Sbjct: 1073 LQEEQLKEQINLIKQKYSKLQQEFD---QLKQFNQQQKEKIENL--QRTAVEQIQIIQRL 1127

Query: 1387 XXXXXXXRVNDAEAKVLELTHQ-LELKDSEIYQKTH-EYTITLTQR-NDEFENVRQQLVE 1443
                   ++ D   +  +L  Q +E+   EI +K   E    L Q+ N++ + +++ L E
Sbjct: 1128 KEQECEQKIKDIITEKEDLMKQTVEITSKEIQKKNKLEIEKLLEQQENNKQQEIQKILKE 1187

Query: 1444 YEKRIEDLTY---EKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVS 1500
            ++++I  +     E+  E  I + K+    +     QKE  I+  K+   +  K   S+S
Sbjct: 1188 HDQQIRSVQQKIEEQNKEDLITKQKLQSELSKCSEFQKEIFIKDQKIASVIQEKEQLSLS 1247

Query: 1501 LNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSF 1560
            + K   + N+ L +E+ +  + Q   EN+E+   T N+ I  L+ + +  + KIQ  V  
Sbjct: 1248 IKKLEIQ-NQKLNDEIIQQKQTQKH-ENEELRQNT-NNRINELEILNKDLNKKIQDFVEI 1304

Query: 1561 ASDTKQ 1566
              D +Q
Sbjct: 1305 LKDKEQ 1310



 Score =  102 bits (245), Expect = 7e-20
 Identities = 230/1106 (20%), Positives = 473/1106 (42%), Gaps = 131/1106 (11%)

Query: 177  EKINEKD-QIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAM---EAEW 232
            +KIN +D + IE  N+                    +    +   +Q+N I +   E+ +
Sbjct: 991  QKINSQDLENIEFLNQEINQLKEINEKNQNELKSEVKQYSHRCQSLQQNLIELQNNESLY 1050

Query: 233  KDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXX 292
             ++  +L ++I+  +++ +S +   + L+     I  ++SKL QE +Q            
Sbjct: 1051 NEKINQLQQEIDDLNMKANSSKLQEEQLKEQINLIKQKYSKLQQEFDQLKQFNQQQKEKI 1110

Query: 293  XXLAKQSIEP----------SCEEK-----TEIEE--KGSLEIANMTELTK-KIELLEHL 334
              L + ++E            CE+K     TE E+  K ++EI +     K K+E+ + L
Sbjct: 1111 ENLQRTAVEQIQIIQRLKEQECEQKIKDIITEKEDLMKQTVEITSKEIQKKNKLEIEKLL 1170

Query: 335  NCQIRQTNKELENKLATMGTESKAVSSPSKKGSP--LISRKSGRNTASKMKSPWSQL--- 389
              Q     +E++  L     + ++V    ++ +   LI+++  ++  SK      ++   
Sbjct: 1171 EQQENNKQQEIQKILKEHDQQIRSVQQKIEEQNKEDLITKQKLQSELSKCSEFQKEIFIK 1230

Query: 390  SSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLI 449
              +  +   +K+     I KLE+  Q LN +      +I +K T            +  I
Sbjct: 1231 DQKIASVIQEKEQLSLSIKKLEIQNQKLNDE------IIQQKQTQKHENEELRQNTNNRI 1284

Query: 450  AQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQ----LKQELNDEI-KDVNVKDLIEK 504
             +L++ ++          +    +D  EI K +EQ    L +E   EI K+++  +    
Sbjct: 1285 NELEILNKD---------LNKKIQDFVEILKDKEQNINNLIKEKEIEIQKNIDFTNCQNI 1335

Query: 505  LKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEEL 564
            LK ++++  QL  +++   + + +++S + L  +       N +K +  N +  +L E L
Sbjct: 1336 LKQSQQENAQLQQQVENIKQQLSQLQSQNALLQQDADNLKQNITKTNKDNLDQKKLIESL 1395

Query: 565  HHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKF 624
                +++   +++K    L  +D     +++S+  K+++  + +       I   E++K 
Sbjct: 1396 Q---EQIKTADQQKSQ-HLRQIDLQQKALVQSE--KEIVNQKMIVNELKSQIQDQENKKL 1449

Query: 625  DLVQELH--ILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVI 682
             L++  H  ++ Q+ D    K   IS+L+      E ++  L++QI      + ++ +  
Sbjct: 1450 ALLKNEHKTMIDQQNDASNQKKI-ISELKQQISTLENQNQQLQKQIGEDCTLQSDIIIF- 1507

Query: 683  ENLKLDKEQLYGTIKDLENDKEDIMNK----LQNYIQENMDLTDKLEKMSAEKISELLAK 738
              LK    QL  T     +   D +N     ++  IQEN +  +KL   S E+  + L  
Sbjct: 1508 --LKDKSNQLIETENKFNHKIIDSINTFYTLIEGLIQENKNKIEKLT--SIEQKQDNLFS 1563

Query: 739  INHEEQSK----IQTQ-FGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRY 793
            I++ +  +    IQ++ F +  K+ E    I+N + +L    S I +  +    ++D + 
Sbjct: 1564 IDYNQLFRKLDTIQSETFKLKKKVIEFSKQIDNQKDQL--LDSNIQQAVQKNLQIKDFKS 1621

Query: 794  SLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKE--- 850
              ER    + +     +K + E T ++ EL  +L  L  HD  +E ++ +I+++  E   
Sbjct: 1622 YFERLQKLVENEENLNKKYFKEITDEQQELCLKLMQLQ-HD--IELEVFKIQNQTLEKVD 1678

Query: 851  -LQKK-------NQILLEE-NQNLQISLSDMQQHYNALVEKANRT--DLAESESTKYQTQ 899
             +QKK       +Q   E  NQNL    S  +  +  +  +A  T  D  + E+   + +
Sbjct: 1679 KVQKKIFIGGIPDQSQFENLNQNLNQIFSKFENDFKQVTTQAQGTYWDYGK-ENRLLERK 1737

Query: 900  LRDLESNLKRITHEHQTLIVQ-KKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIE--Y 956
            L D+   +K++     ++ +Q +KKE++DL+  FN QI   + ++  LN K++  IE  +
Sbjct: 1738 LIDIYEEVKKMREGQFSMKMQLRKKEMQDLD-SFN-QISKNLVNQ--LN-KFQTIIEGLH 1792

Query: 957  VTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNA 1016
            VTQ       Y  N++  N N +       +++      + + +P     +I   N++N 
Sbjct: 1793 VTQFSPVRSSY--NVDLFNQNSDG------DVV------RSSSNP-----FIKNGNQINL 1833

Query: 1017 LLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEE--MQRVSKQLLDS 1074
               +K + +    +K++  Q +  + +S+ E     F    EN+ E+    ++  + + S
Sbjct: 1834 FGSRKSQILQQKFEKVDEKQENEENAISEIEDDDEDFKKFQENLIEDSDQSQIQSKEITS 1893

Query: 1075 KQHNEELQILVREQDDQ-IKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXX 1133
             Q+   LQ   ++QDD+ +       L F+ N   T        I P+ +   N D    
Sbjct: 1894 LQNLSTLQSPQKKQDDKRVSSASAIALAFQ-NEGGTSSNTSLGKISPLRESMTNFDGMRQ 1952

Query: 1134 XXXXXXXXLKVQEEEEFIQE--RSVLQEQSAKLNTELQ----ECYTKIIQ--LETLNTEL 1185
                     + Q    FI E  + + Q     +N+ LQ    E   K ++  +ETL TEL
Sbjct: 1953 SVSRIEN--EDQRNIRFILEELKKIKQNVEKVVNSLLQYNFEEIKIKTLKQTIETLETEL 2010

Query: 1186 TGHDVVNQEQINQLKSKLEQLNTEND 1211
            T +    Q+ +  ++   ++L    D
Sbjct: 2011 TEYKNYYQQSVGYIQGVFDELQQIGD 2036



 Score = 92.3 bits (219), Expect = 1e-16
 Identities = 181/921 (19%), Positives = 389/921 (42%), Gaps = 71/921 (7%)

Query: 212  EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271
            E  + Q    Q+    +  E+K +  +L K++ES+ ++   L          + E+  E 
Sbjct: 892  EQQQNQNILQQQKINQVIEEYKIQLNQLRKELESQQIQYDKL----------KIELQNEQ 941

Query: 272  SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTEL-TKKIEL 330
            +   ++ EQ              L +   E   + +  I++K   E   + ++ ++ +E 
Sbjct: 942  TNYLRQTEQFKSKTEELNQKNKNL-QIEFEQELQNQRNIQQKLHQENEKLQKINSQDLEN 1000

Query: 331  LEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLS 390
            +E LN +I Q  +  E     + +E K  S   +     +     +N  S      +QL 
Sbjct: 1001 IEFLNQEINQLKEINEKNQNELKSEVKQYSHRCQSLQQNLIEL--QNNESLYNEKINQLQ 1058

Query: 391  SETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIA 450
             E    D + K N +++ + E + + +N  L+ ++Y  S+              +   I 
Sbjct: 1059 QEI--DDLNMKANSSKLQE-EQLKEQIN--LIKQKY--SKLQQEFDQLKQFNQQQKEKIE 1111

Query: 451  QLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQL-KQELNDEIKDVNVKDLIEKLKSAE 509
             LQ    + ++    +      + + +I   +E L KQ +    K++  K+ +E  K  E
Sbjct: 1112 NLQRTAVEQIQIIQRLKEQECEQKIKDIITEKEDLMKQTVEITSKEIQKKNKLEIEKLLE 1171

Query: 510  EQITQLNDEIDAANKNMIKVKSNHKLKLKQMQK-TIDNFSKVSDSNKEIVRLTEELHHLS 568
            +Q      EI    K   +   + + K+++  K  +    K+     +     +E+    
Sbjct: 1172 QQENNKQQEIQKILKEHDQQIRSVQQKIEEQNKEDLITKQKLQSELSKCSEFQKEIFIKD 1231

Query: 569  QKVAELEEEKGNLQLHL--VDYDSGRMIESDVYKKMI---EMENLAETRLKAISLLESQK 623
            QK+A + +EK  L L +  ++  + ++ +  + +K     E E L +     I+ LE   
Sbjct: 1232 QKIASVIQEKEQLSLSIKKLEIQNQKLNDEIIQQKQTQKHENEELRQNTNNRINELEILN 1291

Query: 624  FDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALV-- 681
             DL ++   +Q   + ++DK  +I+ L  ++     K++      + L  S++E A +  
Sbjct: 1292 KDLNKK---IQDFVEILKDKEQNINNLIKEKEIEIQKNIDFTNCQNILKQSQQENAQLQQ 1348

Query: 682  -IENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKIN 740
             +EN+K    QL      L+ D +++   +    ++N+D     +K   E + E   +I 
Sbjct: 1349 QVENIKQQLSQLQSQNALLQQDADNLKQNITKTNKDNLD-----QKKLIESLQE---QIK 1400

Query: 741  HEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKAD 800
              +Q K Q    ID  +Q++ L     E E+   K  +  L+  I   E+++ +L +   
Sbjct: 1401 TADQQKSQHLRQID--LQQKALV--QSEKEIVNQKMIVNELKSQIQDQENKKLALLKNEH 1456

Query: 801  QLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKEL-----QKKN 855
            +  + + ++  A ++  I   EL  +++ L + ++ ++KQ+ E      ++      K N
Sbjct: 1457 K--TMIDQQNDASNQKKI-ISELKQQISTLENQNQQLQKQIGEDCTLQSDIIIFLKDKSN 1513

Query: 856  QILLEENQ-NLQI--SLSDMQQHYNALV-EKANRTDLAESESTKYQTQLRDLESN-LKRI 910
            Q++  EN+ N +I  S++        L+ E  N+ +   S   K Q  L  ++ N L R 
Sbjct: 1514 QLIETENKFNHKIIDSINTFYTLIEGLIQENKNKIEKLTSIEQK-QDNLFSIDYNQLFRK 1572

Query: 911  THEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNN 970
                Q+   + KK++    IEF+ QI++  +D+ +     + NI+   Q   Q++++K+ 
Sbjct: 1573 LDTIQSETFKLKKKV----IEFSKQIDNQ-KDQLL-----DSNIQQAVQKNLQIKDFKSY 1622

Query: 971  IENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQ 1030
             E L   VE    +N +   +   +QQ       +   +   ++  +  Q  E++  + +
Sbjct: 1623 FERLQKLVENEENLNKKYFKEITDEQQELCLKLMQLQHDIELEVFKIQNQTLEKVDKVQK 1682

Query: 1031 KINNAQVSYMSMVSDYESKLAQFTTKLEN-MEEEMQRVSKQLLDSKQHNEELQILVREQD 1089
            KI    +   S   +    L Q  +K EN  ++   +      D  + N  L+  + +  
Sbjct: 1683 KIFIGGIPDQSQFENLNQNLNQIFSKFENDFKQVTTQAQGTYWDYGKENRLLERKLIDIY 1742

Query: 1090 DQIKELKETKLTFEMNIPKTE 1110
            +++K+++E + + +M + K E
Sbjct: 1743 EEVKKMREGQFSMKMQLRKKE 1763



 Score = 50.8 bits (116), Expect = 3e-04
 Identities = 131/812 (16%), Positives = 339/812 (41%), Gaps = 73/812 (8%)

Query: 297  KQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTES 356
            +Q+I    +EK EIE + +++  N   + K+ +     N Q++Q  + ++ +L+ + +++
Sbjct: 1309 EQNINNLIKEK-EIEIQKNIDFTNCQNILKQSQ---QENAQLQQQVENIKQQLSQLQSQN 1364

Query: 357  KAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQS 416
              +   +      I++ +  N   K      Q   +T +Q   + + + ++ + + ++QS
Sbjct: 1365 ALLQQDADNLKQNITKTNKDNLDQKKLIESLQEQIKTADQQKSQHLRQIDLQQ-KALVQS 1423

Query: 417  LNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVN 476
              K++V+++ +++E  +                 +  ++ Q        I +    + ++
Sbjct: 1424 -EKEIVNQKMIVNELKSQIQDQENKKLALLKNEHKTMIDQQNDASNQKKI-ISELKQQIS 1481

Query: 477  EIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDE-----IDAAN------KN 525
             +    +QL++++ ++       D+I  LK    Q+ +  ++     ID+ N      + 
Sbjct: 1482 TLENQNQQLQKQIGEDC--TLQSDIIIFLKDKSNQLIETENKFNHKIIDSINTFYTLIEG 1539

Query: 526  MIKVKSNHKLKLKQMQKTIDNFSKVSDSN--KEIVRLTEELHHLSQKVAELEEEKGNLQL 583
            +I+   N   KL  +++  DN   +  +   +++  +  E   L +KV E  ++  N + 
Sbjct: 1540 LIQENKNKIEKLTSIEQKQDNLFSIDYNQLFRKLDTIQSETFKLKKKVIEFSKQIDNQKD 1599

Query: 584  HLVDYDSGRMIESDV----YKKMIE-MENLAETRLKAISLLESQKFDLVQELHI-LQQKY 637
             L+D +  + ++ ++    +K   E ++ L E           +  D  QEL + L Q  
Sbjct: 1600 QLLDSNIQQAVQKNLQIKDFKSYFERLQKLVENEENLNKKYFKEITDEQQELCLKLMQLQ 1659

Query: 638  DEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIK 697
             ++E    ++ ++Q+ Q   ++  V  +  I  +    +      ENL  +  Q++    
Sbjct: 1660 HDIE---LEVFKIQN-QTLEKVDKVQKKIFIGGIPDQSQ-----FENLNQNLNQIFSKF- 1709

Query: 698  DLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAK- 756
              END + +  + Q    +      K  ++   K+ ++  ++    + +   +  +  K 
Sbjct: 1710 --ENDFKQVTTQAQGTYWDY----GKENRLLERKLIDIYEEVKKMREGQFSMKMQLRKKE 1763

Query: 757  IQERDLYIE---NIESELSKYKSRICRLEESIAVMEDRRYSLER-KADQLGSYLQEKQKA 812
            +Q+ D + +   N+ ++L+K+++ I  L  +        Y+++    +  G  ++     
Sbjct: 1764 MQDLDSFNQISKNLVNQLNKFQTIIEGLHVTQFSPVRSSYNVDLFNQNSDGDVVRSSSNP 1823

Query: 813  YSEYTIQEDELVNRLAVLMDH--DRVVEKQ------LLEIEHENKELQKKNQILLEENQN 864
            + +   Q +   +R + ++    ++V EKQ      + EIE ++++ +K  + L+E++  
Sbjct: 1824 FIKNGNQINLFGSRKSQILQQKFEKVDEKQENEENAISEIEDDDEDFKKFQENLIEDSDQ 1883

Query: 865  LQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKE 924
             QI   +       +    N + L   +  +   ++    +      +E  T       +
Sbjct: 1884 SQIQSKE-------ITSLQNLSTLQSPQKKQDDKRVSSASAIALAFQNEGGTSSNTSLGK 1936

Query: 925  IEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIEN-----LNMNVE 979
            I  L  E  T  +   +    +  + ++NI ++ +   +L++ K N+E      L  N E
Sbjct: 1937 ISPLR-ESMTNFDGMRQSVSRIENEDQRNIRFILE---ELKKIKQNVEKVVNSLLQYNFE 1992

Query: 980  ELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSY 1039
            E+    L+   + ++ + T+  +Y +Q +  I  +   L+Q  + +   +Q     +   
Sbjct: 1993 EIKIKTLKQTIETLETELTEYKNYYQQSVGYIQGVFDELQQIGDPVYQFSQMNTIFKKCC 2052

Query: 1040 MSMVSDYESKLAQFTTKLENMEEEMQRVSKQL 1071
              +   Y+ ++       +N   E+ +  KQL
Sbjct: 2053 TDLQEFYKKQIQSQDCAEQNQVIEVIQQVKQL 2084


>UniRef50_A0EHS3 Cluster: Chromosome undetermined scaffold_97, whole
            genome shotgun sequence; n=2; Paramecium tetraurelia|Rep:
            Chromosome undetermined scaffold_97, whole genome shotgun
            sequence - Paramecium tetraurelia
          Length = 2950

 Score =  138 bits (333), Expect = 2e-30
 Identities = 238/1165 (20%), Positives = 486/1165 (41%), Gaps = 91/1165 (7%)

Query: 472  TEDVNE---IAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEID--AANKNM 526
            T+D N+   I +V E  KQ+ +    D+  K+L+ +++  E Q+T    E++   A+   
Sbjct: 554  TQDKNQKTIIDEVNEGTKQQSSKVSLDLQNKELVVEVE--ENQVTFKPKEVEKQGASLEQ 611

Query: 527  IKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLV 586
             ++KS  K  ++Q  K      K  D  K I   ++   +    ++++       Q    
Sbjct: 612  QQMKSQKKPIIQQNYKESIQKQKDDDIEKPIDESSQNQAN-DNTISKIPNTDSQQQFK-- 668

Query: 587  DYDSGRMIESDVYKKMIEMENLAETRLKAISLLES----QKFDLVQELHILQQKYDEVED 642
            D ++ ++  +++  K  + E       K    +E+    Q     Q+++ LQQ     ++
Sbjct: 669  DKNNKQIQIANLDNKQSQKEQTQSISQKEPQKIENPQNQQNNQQKQKVNNLQQNKSSDQN 728

Query: 643  KLADISQL-QSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLEN 701
             L +   L Q+ Q  ++++ +   +  +     +K+      N + DK+Q   T ++ + 
Sbjct: 729  NLENKKDLLQNQQENNQVQKIETTQDGNKNQFLRKQNT----NQQQDKDQQQETQQEHQI 784

Query: 702  DKEDIMNKLQNYIQEN---MDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQ 758
             K+   NKL    +E    ++L  + EK  AE+   L  +   +E+   Q +   D + Q
Sbjct: 785  QKDGQQNKLVEEEKEKDRQLELQRQQEKQQAEQQKRLEEEQKEQEKKDRQLELQKDQERQ 844

Query: 759  ERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTI 818
            + +   +N   E  K K R   L++     E +R   E++  +L    +EK++       
Sbjct: 845  QAEQ--QNKLEEEQKEKERQLELQK-----EQQRQQAEQQK-KLDEEQKEKERQLQLQKE 896

Query: 819  QEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNA 878
            QE +   +   L +  +  E+QL E++ E +  Q + Q  LEE Q  +    ++Q+    
Sbjct: 897  QERQQAEQQKKLEEEQKEKERQL-ELQKEQERQQAEQQKKLEEEQKEKERQLELQKQQEQ 955

Query: 879  LVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIE-DLEIEFNTQIE 937
              ++A +    E E  +   QL +L+   +R   E Q  + +++KE E  LE++   + +
Sbjct: 956  --QQAEQQKKLEDEQKEKNRQL-ELQKEQERQQAEQQKKLEEEQKEKERQLELQKEQERQ 1012

Query: 938  SAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLEL-IDKHVQKQ 996
             A + KK+  E+ E+      QLE Q ++ +   E      EE  +   +L + K  ++Q
Sbjct: 1013 QAEQQKKIEEEQKEQE----RQLEIQKEQERQQAEQQKKLDEEQKEKERQLELQKEQERQ 1068

Query: 997  QTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVS-YMSMVSDYESKLAQFTT 1055
            Q +     E+   E  +     K+++++     +K+   +    + M  + E + A+   
Sbjct: 1069 QVEQQKKLEEEQKEKERKLEQQKEQEKQQAEQKKKLEEEEKERQLEMQKEQERQQAEQQK 1128

Query: 1056 KLENME------------EEMQRVSKQL-LDSKQHNEELQI-LVREQDDQIKELKETKLT 1101
            KLE  +            +E+Q+V +Q  +D +Q  +E  + L +EQ++Q  + ++ KL 
Sbjct: 1129 KLEEEQKEKERQLELQKGQELQQVEQQKKIDEEQKEKERSLGLQKEQENQ--QAEQQKLL 1186

Query: 1102 FEMNIPKTEGMIISSTIEPM-SDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQ 1160
             E N  K   + +    EP  ++    ++             K Q+ ++  Q + + +EQ
Sbjct: 1187 EEENKEKERQLQLQKEQEPQQAEQQKKLEEEQKEKERQLEQQKEQDRQKVEQSKKLEEEQ 1246

Query: 1161 SAK-LNTELQECYT-------KIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDN 1212
              K    ELQ+          K ++ E    E        QEQ  + + KLE+   E + 
Sbjct: 1247 KEKERQIELQKVQENQQTEQQKRLEEEQKEKERQLQLQREQEQQAEQQKKLEEEQQEKER 1306

Query: 1213 LLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQ--LSAFESKYEQ 1270
             L    EL+   +    ++  E  E  +Q   Q+E D Q+ E + +++    A E + EQ
Sbjct: 1307 QL----ELQKQQAEQQKKQEEEQKEKERQLELQKEQDRQQAEEQKKIEEEQKAKELQLEQ 1362

Query: 1271 LLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEE-----HLRNLQEKYADVINQIEILRS 1325
              +  +   +++  K+   +Q    Q +LQ ++E       + L+E+  +   Q+E+ + 
Sbjct: 1363 QKEQERQQAEQQ-KKLEEEQQEKERQLELQKEQEKQQAEQQKRLEEEQKEKERQLELQKE 1421

Query: 1326 EIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQE-QSILNINEENAQLKKSSXXX 1384
            +   +                        E Q  +Q ++ +      E   +L+K     
Sbjct: 1422 QERQQAEQQKKLEEEQKEKERQLELQKEQERQQAEQQKKLEEEQKEKERQLELQKEQERQ 1481

Query: 1385 XXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEY 1444
                          + + LEL  + E + +E  +K  E      ++ +  +   +Q  E 
Sbjct: 1482 LAEQQKKLEEEQKEKERQLELQKEQERQQAEQQKKLEEEQKEKERQLELQKEQERQQAEQ 1541

Query: 1445 EKRIEDLTYEKESELAILRLKMHENANHY-----ETMQKESEIERVKLIEELNV----KI 1495
            +K++E+   EKE +L + + +  + A        E  +KE ++E  K  E   V    K+
Sbjct: 1542 QKKLEEEQKEKERQLELQKQQEQQQAEQQKKLEEEQKEKERQLELQKEQERQQVEQQKKL 1601

Query: 1496 TESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQ 1555
             E     ++  EL K  E+E  +  + Q   + Q+ EIV   D++   Q+     S  + 
Sbjct: 1602 EEDQKEKERQLELQK--EQEKQQAEQQQIDQQQQQKEIVINQDQLQQPQHNAEPQSHPVS 1659

Query: 1556 KHVSFASD-TKQGRDEQLDNTMNKE 1579
               S   D   Q ++   +N++ ++
Sbjct: 1660 LQQSQLIDQNAQNQNNNNNNSLKQQ 1684



 Score =  132 bits (319), Expect = 8e-29
 Identities = 272/1392 (19%), Positives = 569/1392 (40%), Gaps = 100/1392 (7%)

Query: 215  KQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAAR-----FEISL 269
            +QQ  +  E    +E E K+++++  +    KD      E+ NKL E  +      E+  
Sbjct: 808  RQQEKQQAEQQKRLEEEQKEQEKKDRQLELQKDQERQQAEQQNKLEEEQKEKERQLELQK 867

Query: 270  EHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIE 329
            E  +   E ++              L K+      E++ ++EE+   E     EL K+ E
Sbjct: 868  EQQRQQAEQQKKLDEEQKEKERQLQLQKEQERQQAEQQKKLEEE-QKEKERQLELQKEQE 926

Query: 330  LLE-HLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQ 388
              +     ++ +  KE E +L     + +  +   KK       K+ +    K +     
Sbjct: 927  RQQAEQQKKLEEEQKEKERQLELQKQQEQQQAEQQKKLEDEQKEKNRQLELQKEQERQQA 986

Query: 389  LSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTL 448
               + L ++  +K  + E+ K +   Q+  +  +++E    +K+            +   
Sbjct: 987  EQQKKLEEEQKEKERQLELQKEQERQQAEQQKKIEEE----QKEQERQLEIQKEQERQQA 1042

Query: 449  IAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSA 508
              Q +L+ +Q  +   L       +   E  +V++Q K E   + K+  ++   E+ K  
Sbjct: 1043 EQQKKLDEEQKEKERQL-----ELQKEQERQQVEQQKKLEEEQKEKERKLEQQKEQEKQQ 1097

Query: 509  EEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLS 568
             EQ  +L +E     +  ++++   + +  + QK ++   K  +   E+ +  E      
Sbjct: 1098 AEQKKKLEEE---EKERQLEMQKEQERQQAEQQKKLEEEQKEKERQLELQKGQELQQVEQ 1154

Query: 569  QKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQ 628
            QK  + E+++    L L      +  E    +K++E EN  + R   + L + Q+    +
Sbjct: 1155 QKKIDEEQKEKERSLGLQKEQENQQAEQ---QKLLEEENKEKER--QLQLQKEQEPQQAE 1209

Query: 629  ELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLD 688
            +   L+++  E E +L    Q + D+   E +S  LEE+       + EL  V EN + +
Sbjct: 1210 QQKKLEEEQKEKERQLE--QQKEQDRQKVE-QSKKLEEE-QKEKERQIELQKVQENQQTE 1265

Query: 689  KEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQ 748
            +++    +++ + +KE  + +LQ   ++  +   KLE+   EK  +L  +    EQ K Q
Sbjct: 1266 QQK---RLEEEQKEKERQL-QLQREQEQQAEQQKKLEEEQQEKERQLELQKQQAEQQKKQ 1321

Query: 749  TQFGIDAKIQERDLYIENIESELSKYKSRICRLEESI--AVMEDRRYSLERKADQ---LG 803
             +   + K +ER L ++  +      + +    E+      +E ++    ++A+Q   L 
Sbjct: 1322 EE---EQKEKERQLELQKEQDRQQAEEQKKIEEEQKAKELQLEQQKEQERQQAEQQKKLE 1378

Query: 804  SYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQ 863
               QEK++       QE +   +   L +  +  E+Q LE++ E +  Q + Q  LEE Q
Sbjct: 1379 EEQQEKERQLELQKEQEKQQAEQQKRLEEEQKEKERQ-LELQKEQERQQAEQQKKLEEEQ 1437

Query: 864  NLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKK 923
              +    ++Q+      ++A +    E E  + + QL +L+   +R   E Q  + +++K
Sbjct: 1438 KEKERQLELQKEQER--QQAEQQKKLEEEQKEKERQL-ELQKEQERQLAEQQKKLEEEQK 1494

Query: 924  EIE-DLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELN 982
            E E  LE++   + + A + KK+  E+ EK      QLE Q ++ +   E      EE  
Sbjct: 1495 EKERQLELQKEQERQQAEQQKKLEEEQKEKE----RQLELQKEQERQQAEQQKKLEEEQK 1550

Query: 983  KMNLEL-IDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMS 1041
            +   +L + K  ++QQ +     E+   E  +   L K+++ + +   +K+   Q     
Sbjct: 1551 EKERQLELQKQQEQQQAEQQKKLEEEQKEKERQLELQKEQERQQVEQQKKLEEDQ---KE 1607

Query: 1042 MVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLT 1101
                 E +  Q   + E  + + Q+  K+++ ++   ++ Q     Q   +  L++++L 
Sbjct: 1608 KERQLELQKEQEKQQAEQQQIDQQQQQKEIVINQDQLQQPQHNAEPQSHPV-SLQQSQL- 1665

Query: 1102 FEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQS 1161
             + N         +S  +    D + +D             + Q   +F+QE S++ +  
Sbjct: 1666 IDQNAQNQNNNNNNSLKQQTFGDLSKIDQEPGKSPSEIQKSESQHSRKFVQEPSIMIKTP 1725

Query: 1162 AKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELR 1221
             K   + Q+ +      ET N E     VV  EQI   K      +    N   T   L 
Sbjct: 1726 PK---QQQKTF------ETFNEE----KVVQAEQIASPKEVKIGNDIPQYNQTGTFVGL- 1771

Query: 1222 SSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQE 1281
             S     D R  E ++   Q   Q+E    K +++ +   +   S  +++     SS  +
Sbjct: 1772 -SEQQIPDTRRKEGSDNQSQGEQQQEI---KQQNDQKTDKTVSRSSIQKVNSRPPSSKGQ 1827

Query: 1282 ETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXX 1341
            E    +T+E     Q + Q+  +  R+ Q    +     EI++ E  + +          
Sbjct: 1828 EKKAPLTLE-----QQQQQESAQTNRSEQPHDKEKTQSKEIIQQEQNESQSQKPQSQSGI 1882

Query: 1342 XXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAK 1401
                       +T  +   Q +  +    ++ N+ +KKS+              N    +
Sbjct: 1883 RSIKSAGKRGEKTNPEQPSQKEGDNTQQPDQTNS-VKKSNKITPKIQSRPLSGAN----Q 1937

Query: 1402 VLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIED---LTYE-KES 1457
             +EL+     K+S + + T E      +++++ +N   +L E +  IED   LT    + 
Sbjct: 1938 PIELSRPNSTKNS-VKKITIEQQQMKQEQSNQQDNKPPELTESQLSIEDAKRLTQTMSQQ 1996

Query: 1458 ELAILRLKMHENANHYETMQKES-EIERVKLIEELNVKITESVSL------NKQVAELNK 1510
            +L + +L+  E A+H +  Q+ + + +  +   + N +I    SL       K+V + N+
Sbjct: 1997 DLPVKQLQ--ETASHPQLQQQANPQTQNQQQSSKNNSRIQSGKSLQKSDRTQKKVEQPNQ 2054

Query: 1511 ALEEEVAKTNEMQTALENQEIEIV---TLNDEITNLQNMVRASSSKIQKHVSFASDTKQG 1567
               +++ K  + QT  E+Q  EI    T+  E  +     ++S+++ Q   +  S  +  
Sbjct: 2055 DSTQQLEKDQQPQTKSEDQNKEIKDSNTIKSEGKSKGGSNKSSNAQQQPIQNEESKPQSA 2114

Query: 1568 RDEQLDNTMNKE 1579
            +D+Q   T  ++
Sbjct: 2115 KDKQKPVTKEQQ 2126



 Score =  124 bits (300), Expect = 2e-26
 Identities = 212/1076 (19%), Positives = 447/1076 (41%), Gaps = 69/1076 (6%)

Query: 235  EKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXX 294
            + Q+  KD  +K ++I++L+      E  +  IS +  +  +  +               
Sbjct: 662  DSQQQFKDKNNKQIQIANLDNKQSQKEQTQ-SISQKEPQKIENPQNQQNNQQKQKVNNLQ 720

Query: 295  LAKQSIEPSCEEKTEI----EEKGSLEIANMTELTKKIELLEHLNC-----QIRQTNKEL 345
              K S + + E K ++    +E   ++    T+   K + L   N      + +Q   + 
Sbjct: 721  QNKSSDQNNLENKKDLLQNQQENNQVQKIETTQDGNKNQFLRKQNTNQQQDKDQQQETQQ 780

Query: 346  ENKLATMGTESKAVSSPSKKGSPL-ISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINK 404
            E+++   G ++K V    +K   L + R+  +  A + K    +L  E   Q+  KK  +
Sbjct: 781  EHQIQKDGQQNKLVEEEKEKDRQLELQRQQEKQQAEQQK----RLEEEQKEQE--KKDRQ 834

Query: 405  NEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPS 464
             E+ K +   Q+  ++ +++E    +K+            +     Q +L+ +Q  +   
Sbjct: 835  LELQKDQERQQAEQQNKLEEE----QKEKERQLELQKEQQRQQAEQQKKLDEEQKEKERQ 890

Query: 465  LIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANK 524
            L       E   + A+ Q++L++E  ++ + + ++   E+ +   EQ  +L +E     +
Sbjct: 891  L---QLQKEQERQQAEQQKKLEEEQKEKERQLELQK--EQERQQAEQQKKLEEE-QKEKE 944

Query: 525  NMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLH 584
              ++++   + +  + QK +++  K  +   E+ +  E      QK  E E+++   QL 
Sbjct: 945  RQLELQKQQEQQQAEQQKKLEDEQKEKNRQLELQKEQERQQAEQQKKLEEEQKEKERQLE 1004

Query: 585  LVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKL 644
            L      +  E    +K IE E   + R      LE QK    Q+    Q+K DE + + 
Sbjct: 1005 LQKEQERQQAEQ---QKKIEEEQKEQERQ-----LEIQKEQERQQAE-QQKKLDEEQKEK 1055

Query: 645  ADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKE 704
                +LQ +Q   ++      EQ   L   +KE    +E  K  ++Q     K LE +++
Sbjct: 1056 ERQLELQKEQERQQV------EQQKKLEEEQKEKERKLEQQKEQEKQQAEQKKKLEEEEK 1109

Query: 705  DIMNKLQNYIQ-ENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLY 763
            +   ++Q   + +  +   KLE+   EK  +L  +   E Q +++ Q  ID + +E++  
Sbjct: 1110 ERQLEMQKEQERQQAEQQKKLEEEQKEKERQLELQKGQELQ-QVEQQKKIDEEQKEKERS 1168

Query: 764  IENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDEL 823
            +  ++ E    ++   +L E     ++R+  L++  +Q     ++++K   E   +E +L
Sbjct: 1169 L-GLQKEQENQQAEQQKLLEEENKEKERQLQLQK--EQEPQQAEQQKKLEEEQKEKERQL 1225

Query: 824  VNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKA 883
              +     D  +V + + LE E + KE Q + Q + E  Q  Q    + +Q       + 
Sbjct: 1226 EQQKE--QDRQKVEQSKKLEEEQKEKERQIELQKVQENQQTEQQKRLEEEQKEKERQLQL 1283

Query: 884  NRTDLAESESTKY---QTQLRDLESNLKRITHEHQTLIVQKKKEIE-DLEIEFNTQIESA 939
             R    ++E  K    + Q ++ +  L++   E Q    +++KE E  LE++     + A
Sbjct: 1284 QREQEQQAEQQKKLEEEQQEKERQLELQKQQAEQQKKQEEEQKEKERQLELQKEQDRQQA 1343

Query: 940  IRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLEL-IDKHVQKQQT 998
               KK+  E+  K +    QLE Q ++ +   E      EE  +   +L + K  +KQQ 
Sbjct: 1344 EEQKKIEEEQKAKEL----QLEQQKEQERQQAEQQKKLEEEQQEKERQLELQKEQEKQQA 1399

Query: 999  QSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLE 1058
            +     E+   E  +   L K+++ +     +K+   Q      +   + +  Q   + +
Sbjct: 1400 EQQKRLEEEQKEKERQLELQKEQERQQAEQQKKLEEEQKEKERQLELQKEQERQQAEQQK 1459

Query: 1059 NMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTI 1118
             +EEE +   +QL   K+   +L    ++ +++ KE KE +L  +    + +        
Sbjct: 1460 KLEEEQKEKERQLELQKEQERQLAEQQKKLEEEQKE-KERQLELQKEQERQQAEQQKKLE 1518

Query: 1119 EPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSV-LQEQSAKLNTELQECYTKIIQ 1177
            E   +    ++             K  EEE+  +ER + LQ+Q  +   E Q+   +  +
Sbjct: 1519 EEQKEKERQLELQKEQERQQAEQQKKLEEEQKEKERQLELQKQQEQQQAEQQKKLEEEQK 1578

Query: 1178 LETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAE 1237
             +    EL       ++Q+ Q K KLE+   E +  L    E         +Q+  +  +
Sbjct: 1579 EKERQLELQKEQ--ERQQVEQQK-KLEEDQKEKERQLELQKEQE---KQQAEQQQIDQQQ 1632

Query: 1238 LWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVT 1293
              K+ +  ++   Q+ +H    Q      +  QL+D  Q++  +  N   +++Q T
Sbjct: 1633 QQKEIVINQD-QLQQPQHNAEPQSHPVSLQQSQLID--QNAQNQNNNNNNSLKQQT 1685



 Score =  124 bits (298), Expect = 3e-26
 Identities = 257/1376 (18%), Positives = 564/1376 (40%), Gaps = 114/1376 (8%)

Query: 233  KDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXX 292
            K +KQ+  +D   K + I  + E  K  ++++  + L++ +L  E+E+            
Sbjct: 548  KTDKQKT-QDKNQKTI-IDEVNEGTKQ-QSSKVSLDLQNKELVVEVEENQVTFKPKEVEK 604

Query: 293  XXLAKQSIEPSCEEKTEIEE--KGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLA 350
               + +  +   ++K  I++  K S++     ++ K I+          Q N    +K+ 
Sbjct: 605  QGASLEQQQMKSQKKPIIQQNYKESIQKQKDDDIEKPID-----ESSQNQANDNTISKIP 659

Query: 351  TMGTESKAVSSPSKKG--SPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIA 408
               ++ +     +K+   + L +++S +     +     Q      NQ  +++  K ++ 
Sbjct: 660  NTDSQQQFKDKNNKQIQIANLDNKQSQKEQTQSISQKEPQKIENPQNQQNNQQ--KQKVN 717

Query: 409  KLEMVIQSLNKDLVDKEYVIS---EKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSL 465
             L+    S   +L +K+ ++    E +            K+  + +     QQ  +    
Sbjct: 718  NLQQNKSSDQNNLENKKDLLQNQQENNQVQKIETTQDGNKNQFLRKQNTNQQQDKDQQQ- 776

Query: 466  IHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKN 525
                  T+  ++I K  +Q K    ++ KD  ++   ++ K   EQ  +L +E     K 
Sbjct: 777  -----ETQQEHQIQKDGQQNKLVEEEKEKDRQLELQRQQEKQQAEQQKRLEEEQKEQEKK 831

Query: 526  --MIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQL 583
               ++++ + + +  + Q  ++   K  +   E+ +  +      QK  + E+++   QL
Sbjct: 832  DRQLELQKDQERQQAEQQNKLEEEQKEKERQLELQKEQQRQQAEQQKKLDEEQKEKERQL 891

Query: 584  HLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDK 643
             L      +  E    KK+ E +   E +L+   L + Q+    ++   L+++  E E +
Sbjct: 892  QLQKEQERQQAEQQ--KKLEEEQKEKERQLE---LQKEQERQQAEQQKKLEEEQKEKERQ 946

Query: 644  LADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDK 703
            L ++ + Q  Q   + K +  E++        ++L L  E  +   EQ    +++ + +K
Sbjct: 947  L-ELQKQQEQQQAEQQKKLEDEQK-----EKNRQLELQKEQERQQAEQ-QKKLEEEQKEK 999

Query: 704  EDIMNKLQNYIQENMDLTDKLEKMSAEKISEL-LAKINHEEQSKIQTQFGIDAKIQERDL 762
            E  +   +   ++  +   K+E+   E+  +L + K    +Q++ Q +   + K +ER L
Sbjct: 1000 ERQLELQKEQERQQAEQQKKIEEEQKEQERQLEIQKEQERQQAEQQKKLDEEQKEKERQL 1059

Query: 763  YIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDE 822
                   EL K + R  +  E    +E+ +   ERK +Q     QEKQ+A  +  ++E+E
Sbjct: 1060 -------ELQKEQER--QQVEQQKKLEEEQKEKERKLEQQKE--QEKQQAEQKKKLEEEE 1108

Query: 823  LVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEK 882
               +L +  + +R   +Q  ++E E KE  K+ Q+ L++ Q LQ             VE+
Sbjct: 1109 KERQLEMQKEQERQQAEQQKKLEEEQKE--KERQLELQKGQELQ------------QVEQ 1154

Query: 883  ANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIE-DLEIEFNTQIESAIR 941
              + D    E  K + +   L+   +    E Q L+ ++ KE E  L+++   + + A +
Sbjct: 1155 QKKID----EEQKEKERSLGLQKEQENQQAEQQKLLEEENKEKERQLQLQKEQEPQQAEQ 1210

Query: 942  DKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLEL-IDKHVQKQQTQS 1000
             KK+  E+ EK      QLE Q ++ +  +E      EE  +   ++ + K  + QQT+ 
Sbjct: 1211 QKKLEEEQKEKE----RQLEQQKEQDRQKVEQSKKLEEEQKEKERQIELQKVQENQQTEQ 1266

Query: 1001 PDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENM 1060
                E+   E  K   L  Q+++E  A  QK    ++       + + +L +   + +  
Sbjct: 1267 QKRLEEEQKE--KERQLQLQREQEQQAEQQK----KLEEEQQEKERQLELQKQQAEQQKK 1320

Query: 1061 EEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEP 1120
            +EE Q+  ++ L+ ++  +  Q   +++ ++ ++ KE +L  +    + +        E 
Sbjct: 1321 QEEEQKEKERQLELQKEQDRQQAEEQKKIEEEQKAKELQLEQQKEQERQQAEQQKKLEEE 1380

Query: 1121 MSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSV-LQEQSAKLNTELQECYTKIIQLE 1179
              +    ++             K  EEE+  +ER + LQ++  +   E Q+   +  + +
Sbjct: 1381 QQEKERQLELQKEQEKQQAEQQKRLEEEQKEKERQLELQKEQERQQAEQQKKLEEEQKEK 1440

Query: 1180 TLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELW 1239
                EL       ++Q  Q K KLE+   E +  L    E    ++    +   E  E  
Sbjct: 1441 ERQLELQKEQ--ERQQAEQQK-KLEEEQKEKERQLELQKEQERQLAEQQKKLEEEQKEKE 1497

Query: 1240 KQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTS----- 1294
            +Q   Q+E + Q+ E + +++    E + +  L   Q   Q E  K +  EQ        
Sbjct: 1498 RQLELQKEQERQQAEQQKKLEEEQKEKERQLELQKEQERQQAEQQKKLEEEQKEKERQLE 1557

Query: 1295 LQNKLQDKE-EHLRNLQEKYADVINQIEIL----RSEIEDE-KVAFXXXXXXXXXXXXXX 1348
            LQ + + ++ E  + L+E+  +   Q+E+     R ++E + K+                
Sbjct: 1558 LQKQQEQQQAEQQKKLEEEQKEKERQLELQKEQERQQVEQQKKLEEDQKEKERQLELQKE 1617

Query: 1349 XXDLRTENQSYKQMQEQSILNINEENAQL-KKSSXXXXXXXXXXXXRVNDAEAKVLELTH 1407
                + E Q   Q Q+Q  + IN++  Q  + ++            ++ D  A+     +
Sbjct: 1618 QEKQQAEQQQIDQQQQQKEIVINQDQLQQPQHNAEPQSHPVSLQQSQLIDQNAQ-----N 1672

Query: 1408 QLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMH 1467
            Q    ++ + Q+T      + Q   +  +  Q+      R     + +E  + +++    
Sbjct: 1673 QNNNNNNSLKQQTFGDLSKIDQEPGKSPSEIQKSESQHSR----KFVQEPSI-MIKTPPK 1727

Query: 1468 ENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQ---- 1523
            +    +ET  +E  ++  ++     VKI   +    Q        E+++  T   +    
Sbjct: 1728 QQQKTFETFNEEKVVQAEQIASPKEVKIGNDIPQYNQTGTFVGLSEQQIPDTRRKEGSDN 1787

Query: 1524 TALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKE 1579
             +   Q+ EI   ND+ T+       S S IQK V+    + +G++++   T+ ++
Sbjct: 1788 QSQGEQQQEIKQQNDQKTD----KTVSRSSIQK-VNSRPPSSKGQEKKAPLTLEQQ 1838



 Score =  119 bits (287), Expect = 6e-25
 Identities = 193/1042 (18%), Positives = 444/1042 (42%), Gaps = 67/1042 (6%)

Query: 527  IKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLV 586
            ++ + NH     Q QK  +  S  ++ N EI            K     +EK        
Sbjct: 452  LEQQKNHSGDNSQHQKFHEESS--NEMNNEIPNQQRTKTEEQGKAKNQFKEKFGFSESHP 509

Query: 587  DYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLAD 646
            D +  +  E   ++   +   L+  + +++ + ESQ+    ++     +    + D++ +
Sbjct: 510  DQEPQQPKEQFTFQGNSDPYRLSSIKERSMEIGESQRVKTDKQ-KTQDKNQKTIIDEVNE 568

Query: 647  ISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDL--ENDKE 704
             ++ QS +V  ++++  L  +++    + K   +  +   L+++Q+    K +  +N KE
Sbjct: 569  GTKQQSSKVSLDLQNKELVVEVEENQVTFKPKEVEKQGASLEQQQMKSQKKPIIQQNYKE 628

Query: 705  DIMNKLQNYIQENMDL----------------TDKLEKMSAEKISEL-LAKINHEEQSKI 747
             I  +  + I++ +D                 TD  ++   +   ++ +A +++++  K 
Sbjct: 629  SIQKQKDDDIEKPIDESSQNQANDNTISKIPNTDSQQQFKDKNNKQIQIANLDNKQSQKE 688

Query: 748  QTQFGIDAKIQERDLYIENIESELS-KYKSRICRLEESIAVMEDRRYSLERKADQLGSYL 806
            QTQ  I  K  ++   IEN +++ + + K ++  L+++ +  ++   +LE K D L +  
Sbjct: 689  QTQ-SISQKEPQK---IENPQNQQNNQQKQKVNNLQQNKSSDQN---NLENKKDLLQNQQ 741

Query: 807  QEKQKAYSEYTIQ--EDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQ- 863
            +  Q    E T    +++ + +       D+  ++Q  + EH+ ++  ++N+++ EE + 
Sbjct: 742  ENNQVQKIETTQDGNKNQFLRKQNTNQQQDKD-QQQETQQEHQIQKDGQQNKLVEEEKEK 800

Query: 864  NLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKK 923
            + Q+ L   Q+   A  E+  R +  + E  K   QL +L+ + +R   E Q  + +++K
Sbjct: 801  DRQLELQRQQEKQQA--EQQKRLEEEQKEQEKKDRQL-ELQKDQERQQAEQQNKLEEEQK 857

Query: 924  EIE-DLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELN 982
            E E  LE++   Q + A + KK+  E+ EK      QL+ Q ++ +   E      EE  
Sbjct: 858  EKERQLELQKEQQRQQAEQQKKLDEEQKEKE----RQLQLQKEQERQQAEQQKKLEEEQK 913

Query: 983  KMNLEL-IDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMS 1041
            +   +L + K  ++QQ +     E+   E  +   L KQ++++     +K+ + Q     
Sbjct: 914  EKERQLELQKEQERQQAEQQKKLEEEQKEKERQLELQKQQEQQQAEQQKKLEDEQKEKNR 973

Query: 1042 MVSDYESKLAQFTTKLENMEEEMQRVSKQL-LDSKQHNEELQILVREQDDQIKELKETKL 1100
             +   + +  Q   + + +EEE +   +QL L  +Q  ++ +   + +++Q ++ ++ ++
Sbjct: 974  QLELQKEQERQQAEQQKKLEEEQKEKERQLELQKEQERQQAEQQKKIEEEQKEQERQLEI 1033

Query: 1101 TFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQ 1160
              E    + E        E   +    ++             K  EEE+  +ER + Q++
Sbjct: 1034 QKEQERQQAEQQ--KKLDEEQKEKERQLELQKEQERQQVEQQKKLEEEQKEKERKLEQQK 1091

Query: 1161 SAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAEL 1220
              +     Q+   K ++ E    +L       ++Q  Q K KLE+   E +  L    + 
Sbjct: 1092 EQEKQQAEQK---KKLEEEEKERQLEMQKEQERQQAEQQK-KLEEEQKEKERQLE--LQK 1145

Query: 1221 RSSISSAVDQRGFEIAELWKQHL--AQREADFQKTEHELRVQLSAFESKYEQLLDSVQSS 1278
               +     Q+  +  +  K+     Q+E + Q+ E +  ++    E + +  L   Q  
Sbjct: 1146 GQELQQVEQQKKIDEEQKEKERSLGLQKEQENQQAEQQKLLEEENKEKERQLQLQKEQEP 1205

Query: 1279 TQEETNKIVTMEQVTS----LQNKLQDKE--EHLRNLQEKYADVINQIEILRSEIEDEKV 1332
             Q E  K +  EQ        Q K QD++  E  + L+E+  +   QIE+ + + E+++ 
Sbjct: 1206 QQAEQQKKLEEEQKEKERQLEQQKEQDRQKVEQSKKLEEEQKEKERQIELQKVQ-ENQQ- 1263

Query: 1333 AFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXX 1392
                               L+ + +  +Q ++Q  L   ++  + +              
Sbjct: 1264 --TEQQKRLEEEQKEKERQLQLQREQEQQAEQQKKLEEEQQEKERQLELQKQQAEQQKKQ 1321

Query: 1393 XRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLT 1452
                  + + LEL  + + + +E  +K  E       + ++ +   +Q  E +K++E+  
Sbjct: 1322 EEEQKEKERQLELQKEQDRQQAEEQKKIEEEQKAKELQLEQQKEQERQQAEQQKKLEEEQ 1381

Query: 1453 YEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKAL 1512
             EKE +L + + +  + A   + +++E + E+ + +E    +  +     K++ E  K  
Sbjct: 1382 QEKERQLELQKEQEKQQAEQQKRLEEEQK-EKERQLELQKEQERQQAEQQKKLEEEQKEK 1440

Query: 1513 EE--EVAKTNEMQTALENQEIE 1532
            E   E+ K  E Q A + +++E
Sbjct: 1441 ERQLELQKEQERQQAEQQKKLE 1462



 Score =  105 bits (253), Expect = 8e-21
 Identities = 165/821 (20%), Positives = 352/821 (42%), Gaps = 54/821 (6%)

Query: 212  EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDV-RISSLEEANKLLEAARFEISLE 270
            +D ++Q  + Q+N +  E + K+ +  L K+ + +   +   L+E  K  E  + ++  E
Sbjct: 839  KDQERQQAE-QQNKLEEEQKEKERQLELQKEQQRQQAEQQKKLDEEQKEKER-QLQLQKE 896

Query: 271  HSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIEL 330
              +   E ++              L K+      E++ ++EE+   E     EL K+ E 
Sbjct: 897  QERQQAEQQKKLEEEQKEKERQLELQKEQERQQAEQQKKLEEEQK-EKERQLELQKQQEQ 955

Query: 331  LE-HLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQL 389
             +     ++    KE   +L     + +  +   KK       K  +    K +      
Sbjct: 956  QQAEQQKKLEDEQKEKNRQLELQKEQERQQAEQQKKLEEEQKEKERQLELQKEQERQQAE 1015

Query: 390  SSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLI 449
              + + ++  ++  + EI K +   Q+  +  +D+E    +K+            +  + 
Sbjct: 1016 QQKKIEEEQKEQERQLEIQKEQERQQAEQQKKLDEE----QKEKERQLELQKEQERQQVE 1071

Query: 450  AQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAE 509
             Q +LE +Q  +   L       E   E  K Q + K++L +E K+  ++   E+ +   
Sbjct: 1072 QQKKLEEEQKEKERKL-------EQQKEQEKQQAEQKKKLEEEEKERQLEMQKEQERQQA 1124

Query: 510  EQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQ 569
            EQ  +L +E     +  ++++   +L+  + QK ID   K  + +  + +  E      Q
Sbjct: 1125 EQQKKLEEE-QKEKERQLELQKGQELQQVEQQKKIDEEQKEKERSLGLQKEQENQQAEQQ 1183

Query: 570  KVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQE 629
            K+ E E ++   QL L      +  E    KK+ E +   E +L+     + QK   V++
Sbjct: 1184 KLLEEENKEKERQLQLQKEQEPQQAEQQ--KKLEEEQKEKERQLEQQKEQDRQK---VEQ 1238

Query: 630  LHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLE--EQIDALSASKKELALVIENLKL 687
               L+++  E E ++ ++ ++Q +Q   + K +  E  E+   L   +++     +  KL
Sbjct: 1239 SKKLEEEQKEKERQI-ELQKVQENQQTEQQKRLEEEQKEKERQLQLQREQEQQAEQQKKL 1297

Query: 688  DKEQLYGTIKDLENDKEDI-MNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSK 746
            ++EQ     + LE  K+     K Q   Q+  +   +L+K    + +E   KI  E+++K
Sbjct: 1298 EEEQQEKE-RQLELQKQQAEQQKKQEEEQKEKERQLELQKEQDRQQAEEQKKIEEEQKAK 1356

Query: 747  ---IQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLG 803
               ++ Q   + +  E+   +E  + E  + +  + + +E     + +R   E+K  +  
Sbjct: 1357 ELQLEQQKEQERQQAEQQKKLEEEQQEKER-QLELQKEQEKQQAEQQKRLEEEQKEKERQ 1415

Query: 804  SYLQ---EKQKAYSEYTIQED--ELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQIL 858
              LQ   E+Q+A  +  ++E+  E   +L +  + +R   +Q  ++E E KE +++ ++ 
Sbjct: 1416 LELQKEQERQQAEQQKKLEEEQKEKERQLELQKEQERQQAEQQKKLEEEQKEKERQLELQ 1475

Query: 859  LEENQNL---QISLSDMQQHYNALVE--------KANRTDLAESESTKYQTQLRDLESNL 907
             E+ + L   Q  L + Q+     +E        +A +    E E  + + QL +L+   
Sbjct: 1476 KEQERQLAEQQKKLEEEQKEKERQLELQKEQERQQAEQQKKLEEEQKEKERQL-ELQKEQ 1534

Query: 908  KRITHEHQTLIVQKKKEIE-DLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQE 966
            +R   E Q  + +++KE E  LE++   + + A + KK+  E+ EK      QLE Q ++
Sbjct: 1535 ERQQAEQQKKLEEEQKEKERQLELQKQQEQQQAEQQKKLEEEQKEKE----RQLELQKEQ 1590

Query: 967  YKNNIENLNMNVEELNKMNLEL-IDKHVQKQQTQSPDYTEQ 1006
             +  +E      E+  +   +L + K  +KQQ +     +Q
Sbjct: 1591 ERQQVEQQKKLEEDQKEKERQLELQKEQEKQQAEQQQIDQQ 1631



 Score = 70.1 bits (164), Expect = 5e-10
 Identities = 137/702 (19%), Positives = 280/702 (39%), Gaps = 48/702 (6%)

Query: 882  KANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIR 941
            K    ++ ES+  K   Q +  + N K I  E      Q+  ++  L+++ N ++   + 
Sbjct: 535  KERSMEIGESQRVKTDKQ-KTQDKNQKTIIDEVNEGTKQQSSKVS-LDLQ-NKELVVEVE 591

Query: 942  DKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHV-QKQQTQS 1000
            + +V  +  E   +  +  + Q++  K  I   N   E + K   + I+K + +  Q Q+
Sbjct: 592  ENQVTFKPKEVEKQGASLEQQQMKSQKKPIIQQNYK-ESIQKQKDDDIEKPIDESSQNQA 650

Query: 1001 PDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYE-SKLAQFTTKLEN 1059
             D T   I   +       + +++I   N     +Q      +S  E  K+     +  N
Sbjct: 651  NDNTISKIPNTDSQQQFKDKNNKQIQIANLDNKQSQKEQTQSISQKEPQKIENPQNQQNN 710

Query: 1060 MEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIE 1119
             +++     +Q   S Q+N E +  + +   +  ++++ + T + N  K + +   +T +
Sbjct: 711  QQKQKVNNLQQNKSSDQNNLENKKDLLQNQQENNQVQKIETTQDGN--KNQFLRKQNTNQ 768

Query: 1120 PMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQE-CYTKIIQL 1178
                D                  K+ EEE+    +  LQ Q  K   E Q+    +  + 
Sbjct: 769  QQDKDQQQETQQEHQIQKDGQQNKLVEEEKEKDRQLELQRQQEKQQAEQQKRLEEEQKEQ 828

Query: 1179 ETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAEL 1238
            E  + +L       ++Q  Q ++KLE+   E +  L    E +   +    +   E  E 
Sbjct: 829  EKKDRQLELQKDQERQQAEQ-QNKLEEEQKEKERQLELQKEQQRQQAEQQKKLDEEQKEK 887

Query: 1239 WKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNK 1298
             +Q   Q+E + Q+ E + +++    E + +  L   Q   Q E  K +  EQ      K
Sbjct: 888  ERQLQLQKEQERQQAEQQKKLEEEQKEKERQLELQKEQERQQAEQQKKLEEEQ------K 941

Query: 1299 LQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQS 1358
             ++++  L+  QE+      Q E  + ++EDE+                     R + + 
Sbjct: 942  EKERQLELQKQQEQ-----QQAE-QQKKLEDEQ-------KEKNRQLELQKEQERQQAEQ 988

Query: 1359 YKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQ 1418
             K+++E+      E   +L+K                   + + LE+  + E + +E  +
Sbjct: 989  QKKLEEEQ--KEKERQLELQKEQERQQAEQQKKIEEEQKEQERQLEIQKEQERQQAEQQK 1046

Query: 1419 KTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQK 1478
            K  E      ++ +  +   +Q VE +K++E+   EKE +L   + +  + A   + +++
Sbjct: 1047 KLDEEQKEKERQLELQKEQERQQVEQQKKLEEEQKEKERKLEQQKEQEKQQAEQKKKLEE 1106

Query: 1479 ESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALE-NQEIEIVTLN 1537
            E +  ++++ +E            +Q AE  K LEEE  K  E Q  L+  QE++ V   
Sbjct: 1107 EEKERQLEMQKEQE----------RQQAEQQKKLEEE-QKEKERQLELQKGQELQQVEQQ 1155

Query: 1538 DEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKE 1579
             +I   Q   +  S  +QK      + +Q   ++L    NKE
Sbjct: 1156 KKIDEEQK-EKERSLGLQKE----QENQQAEQQKLLEEENKE 1192



 Score = 67.7 bits (158), Expect = 2e-09
 Identities = 195/1092 (17%), Positives = 432/1092 (39%), Gaps = 69/1092 (6%)

Query: 212  EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFE----I 267
            E  K+Q  +  E    +E E K EK+R    IE + V+ +   E  K LE  + E    +
Sbjct: 1226 EQQKEQDRQKVEQSKKLEEEQK-EKER---QIELQKVQENQQTEQQKRLEEEQKEKERQL 1281

Query: 268  SLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKK 327
             L+  +  Q+ EQ              L  Q  +   ++K E E+K       + +   +
Sbjct: 1282 QLQREQ-EQQAEQQKKLEEEQQEKERQLELQKQQAEQQKKQEEEQKEKERQLELQKEQDR 1340

Query: 328  IELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWS 387
             +  E    +  Q  KEL+  L     + +  +   KK       K  +    K +    
Sbjct: 1341 QQAEEQKKIEEEQKAKELQ--LEQQKEQERQQAEQQKKLEEEQQEKERQLELQKEQEKQQ 1398

Query: 388  QLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDT 447
                + L ++  +K  + E+ K +   Q+  +  +++E    +K+            +  
Sbjct: 1399 AEQQKRLEEEQKEKERQLELQKEQERQQAEQQKKLEEE----QKEKERQLELQKEQERQQ 1454

Query: 448  LIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKS 507
               Q +LE +Q  +   L       E   ++A+ Q++L++E  ++ + + ++   E+ + 
Sbjct: 1455 AEQQKKLEEEQKEKERQL---ELQKEQERQLAEQQKKLEEEQKEKERQLELQK--EQERQ 1509

Query: 508  AEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHL 567
              EQ  +L +E     +  ++++   + +  + QK ++   K  +   E+ +  E+    
Sbjct: 1510 QAEQQKKLEEE-QKEKERQLELQKEQERQQAEQQKKLEEEQKEKERQLELQKQQEQQQAE 1568

Query: 568  SQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLV 627
             QK  E E+++   QL L      + +E    KK+ E +   E +L+   L + Q+    
Sbjct: 1569 QQKKLEEEQKEKERQLELQKEQERQQVEQQ--KKLEEDQKEKERQLE---LQKEQEKQQA 1623

Query: 628  QELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKL 687
            ++  I QQ+  + ++ + +  QLQ  Q  +E +S  +  Q   L     +      N  L
Sbjct: 1624 EQQQIDQQQ--QQKEIVINQDQLQQPQHNAEPQSHPVSLQQSQLIDQNAQNQNNNNNNSL 1681

Query: 688  DKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKI 747
             K+Q +G +  ++ +     +++Q    E+      +++ S      ++ K   ++Q K 
Sbjct: 1682 -KQQTFGDLSKIDQEPGKSPSEIQK--SESQHSRKFVQEPS------IMIKTPPKQQQKT 1732

Query: 748  QTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQ 807
               F  + K+ + +      E ++     +  +    + + E +     RK         
Sbjct: 1733 FETFN-EEKVVQAEQIASPKEVKIGNDIPQYNQTGTFVGLSEQQIPDTRRKEGSDNQSQG 1791

Query: 808  EKQKAYSEYTIQE-DELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQ 866
            E+Q+   +   Q+ D+ V+R ++   + R            +K  +KK  + LE+ Q  +
Sbjct: 1792 EQQQEIKQQNDQKTDKTVSRSSIQKVNSR---------PPSSKGQEKKAPLTLEQQQQQE 1842

Query: 867  ISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIE 926
             + ++  +  +   EK    ++ + E  + Q+Q    +S ++ I    +       ++  
Sbjct: 1843 SAQTNRSEQPHDK-EKTQSKEIIQQEQNESQSQKPQSQSGIRSIKSAGKRGEKTNPEQPS 1901

Query: 927  DLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMN-VEELNKMN 985
              E + NTQ        K  N K    I+    L    Q  + +  N   N V+++    
Sbjct: 1902 QKEGD-NTQQPDQTNSVKKSN-KITPKIQS-RPLSGANQPIELSRPNSTKNSVKKITIEQ 1958

Query: 986  LELIDKHVQKQQTQSPDYTEQY--INEINKLNALLKQKDEEIIALNQKINNAQVSYMS-- 1041
             ++  +   +Q  + P+ TE    I +  +L   + Q+D  +  L +  ++ Q+   +  
Sbjct: 1959 QQMKQEQSNQQDNKPPELTESQLSIEDAKRLTQTMSQQDLPVKQLQETASHPQLQQQANP 2018

Query: 1042 -----MVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELK 1096
                   S   +   Q    L+  +   ++V +   DS Q  E+ Q    + +DQ KE+K
Sbjct: 2019 QTQNQQQSSKNNSRIQSGKSLQKSDRTQKKVEQPNQDSTQQLEKDQQPQTKSEDQNKEIK 2078

Query: 1097 ETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSV 1156
            ++  T +    K++G    S+        N                K Q++    Q+  V
Sbjct: 2079 DSN-TIKSE-GKSKGGSNKSSNAQQQPIQNEESKPQSAKDKQKPVTKEQQQPVQNQDEQV 2136

Query: 1157 LQEQSA--KLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLL 1214
             ++Q    ++  +  +     I++++ ++ + G   +NQ + +  K   + +  E + ++
Sbjct: 2137 FRQQQTIEQIKDKANQEDIPQIKVQSPHSSMKGSQDMNQLEASLHKDD-QVVEQEQEQVV 2195

Query: 1215 STVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQL-LD 1273
                +++  + S+  Q   +  E   Q   ++E   Q  + +++   S    + EQ  + 
Sbjct: 2196 EQNQDIQ-EVRSSNQQDQEQANENAIQQNNEQEKQEQNNDQDVKGPKSEQNGQEEQEGMK 2254

Query: 1274 SVQSSTQEETNK 1285
            S  S+  ++TNK
Sbjct: 2255 SSDSNRSQKTNK 2266


>UniRef50_A0D3I1 Cluster: Chromosome undetermined scaffold_36, whole
            genome shotgun sequence; n=2; Paramecium tetraurelia|Rep:
            Chromosome undetermined scaffold_36, whole genome shotgun
            sequence - Paramecium tetraurelia
          Length = 1351

 Score =  137 bits (332), Expect = 2e-30
 Identities = 212/1085 (19%), Positives = 474/1085 (43%), Gaps = 87/1085 (8%)

Query: 478  IAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKL 537
            + ++QEQ KQ   D++ D N+    E++   E+Q++Q+  ++  A K+   +  N+K  +
Sbjct: 267  VLQLQEQRKQI--DKMVDQNIYQ--EQICQYEQQLSQIQSQLRQAQKDNENLTQNYKKAM 322

Query: 538  KQMQK-TIDNFSKVSDSNKEIVRLTEEL-HHLSQKVAELEEEKGNLQLHLVDYDSGRMIE 595
            ++  K +I++  + + S K+ ++  EE+  +  Q  + LE    + Q   +++++    +
Sbjct: 323  QKYNKLSINSEEQNTSSLKQRLQELEEICKNKDQLYSVLERSNNDSQHRNINFENQITQQ 382

Query: 596  SD----VYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQ 651
            +     +  K+ E + L +++ ++++ L  Q  +L  +   LQQ      +K+ ++S+  
Sbjct: 383  NQQLLQLKNKLDEKDILIDSQKESLNNLNLQLLNLQNQNCSLQQNEKIHNEKIDELSK-- 440

Query: 652  SDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQ 711
                    + +  +EQI+  S   K+     ++L LD +       ++EN  + + NK  
Sbjct: 441  --------QIIQQQEQINQQSIEIKKQCE--DHLSLDNQ-------NIENLTQQLNNK-N 482

Query: 712  NYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESEL 771
            N + E     ++ ++    ++ ELL +I  ++Q K Q Q  ++ K  E++   +N ++EL
Sbjct: 483  NELAEYQTQCEQQKQKHQLEVEELLKQIQQQKQEKEQIQADLEQKYMEKE---KNFQNEL 539

Query: 772  SKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQ--EDELVNRLAV 829
             + + R   L   + V+  +   L++  +   +  Q  +K + +   +  E +L N+L  
Sbjct: 540  KQQQEREEELSTKVQVLIQQTNQLQQLINDSTNQAQVMRKLFLDPQNESAEADLPNQLME 599

Query: 830  LMDHDRVVEKQLLE-IEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKAN-RTD 887
            L     +   +L + +E  +K++Q+      + + N Q  L +  Q     + +A  + D
Sbjct: 600  LNKAIALKFCKLKQDLEQNSKQIQEYEIEDSKNSYNQQSLLIEQLQLTTIELNQAKQKID 659

Query: 888  LAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKK--EIEDLEIEFNTQIESAIRDKKV 945
              +SE+   Q Q+   ++N + + + +Q  + Q +K   +++LEI+    I+ +I +K++
Sbjct: 660  NLQSENALLQKQM---QTNSEFLNNLNQLTLQQNEKIQNLQNLEIQNKDLIQQSISEKQI 716

Query: 946  LNEKYEKNIEYVTQ----------LEAQLQEYKNNIENLNMNVEELNKMNLE--LIDKHV 993
              +  E+NI +  Q          L+ ++ + ++ I NL+  + +LN+ N E  +I++ +
Sbjct: 717  NQQLSEQNIIFDQQNQDLQIKLQALQIEILKKEDLINNLSSKISQLNQQNQEQVIINEQL 776

Query: 994  QKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQF 1053
            Q Q  +S   T++   E         Q++E +   N  +    +     ++  + ++   
Sbjct: 777  QFQIKESIHNTQELQQENQISKTQYDQQNENLTMQNSTLEKEIIQLKDQITILDEQVNNL 836

Query: 1054 TTKLENME--EEMQRVSKQLLDSKQHNEELQ--ILVREQD-----DQIKELKETKLTFEM 1104
              K++ +E    +++   Q  D  Q  +++Q  + V+EQD     DQ+++  + +   + 
Sbjct: 837  NQKIKELEILNSLKQDEIQQQDQIQQQDQIQQQVQVQEQDQTQQYDQLQQQVQLQDQVQQ 896

Query: 1105 --NIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEE---EEFIQERSVLQE 1159
              N    +  II  T + +      ++            L    E   E+  + +  ++E
Sbjct: 897  KDNQDNKQNEIIQQTYQEIGIQTEQLEQQQVINLELNSQLAEPLEINKEQHSKLQQQIEE 956

Query: 1160 QSAKLN---TELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLST 1216
             + +LN   T LQ+    I Q++  NT L     +   +  +   ++EQL   N+   S 
Sbjct: 957  LTIQLNQQTTALQQAQNDIDQMKIENTSLVKSHEMQLLREGEFTLQIEQLIEINEQKSSK 1016

Query: 1217 VAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQ 1276
            + EL + I  +  Q   +I EL +Q L     ++ K +  ++  +   E K  +L + ++
Sbjct: 1017 IEELETQIKESQLQYQNDIQEL-QQQLFTENDEWLKEKEIIQQYIDQLEHKGLELTNQIK 1075

Query: 1277 SSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXX 1336
                E  N     +Q++     LQ   E  + L+++  +   + E    EI  + +    
Sbjct: 1076 VKDDEIQNIQKQNQQLSDQLEGLQIVNEKAQQLEKQCLENKQKFEQQIDEINLKNILKNN 1135

Query: 1337 XXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVN 1396
                          D + +    K+  E+   +I E++    K +            R+ 
Sbjct: 1136 DFIKQIQQLQQQSQDDQVKLLELKKQLEEKEESIKEKDG---KHAIEIQLITNNYVNRLK 1192

Query: 1397 DAEAKVLELT------HQLELKDSEIYQKTHEYTITLTQRNDE-FENVRQQLVEYEKRIE 1449
            D +  +  L        Q+EL    + +        L Q+  E FE +++  +  EK I+
Sbjct: 1193 DKDDVIQNLQQEIQSYQQVELDQQNLIKFLENVKENLEQQKSENFEYIQEIQLTNEKIIQ 1252

Query: 1450 DLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELN 1509
                 ++ EL I +L++       E    E E E++ +       + E+ SLN+     N
Sbjct: 1253 Q---SEQQELQINQLQV--TIKELEQKNHELETEKINISNNYQQALIEAQSLNQTQDNSN 1307

Query: 1510 KALEE 1514
            + +E+
Sbjct: 1308 EIIEK 1312



 Score =  133 bits (321), Expect = 4e-29
 Identities = 216/1048 (20%), Positives = 437/1048 (41%), Gaps = 95/1048 (9%)

Query: 331  LEHLNCQIRQTNKELEN-----KLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSP 385
            L  +  Q+RQ  K+ EN     K A       +++S  +  S L  R        K K  
Sbjct: 297  LSQIQSQLRQAQKDNENLTQNYKKAMQKYNKLSINSEEQNTSSLKQRLQELEEICKNKDQ 356

Query: 386  WSQLSSETLNQDTDKKIN-KNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXG 444
               +   + N    + IN +N+I +    +  L   L +K+ +I  +             
Sbjct: 357  LYSVLERSNNDSQHRNINFENQITQQNQQLLQLKNKLDEKDILIDSQKESLNNLNLQLLN 416

Query: 445  KDTLIAQLQLEHQQHMEGPSLI--HVGTNTEDVNEIA-KVQEQLKQELNDEIKDVNVKDL 501
                   LQ   + H E    +   +    E +N+ + ++++Q +  L+  + + N+++L
Sbjct: 417  LQNQNCSLQQNEKIHNEKIDELSKQIIQQQEQINQQSIEIKKQCEDHLS--LDNQNIENL 474

Query: 502  IEKLKSAEEQITQLNDEIDAANKN-------MIKVKSNHKLKLKQMQKTIDN--FSKVSD 552
             ++L +   ++ +   + +   +        ++K     K + +Q+Q  ++     K  +
Sbjct: 475  TQQLNNKNNELAEYQTQCEQQKQKHQLEVEELLKQIQQQKQEKEQIQADLEQKYMEKEKN 534

Query: 553  SNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVY------KKMIEME 606
               E+ +  E    LS KV  L ++   LQ  + D  +   +   ++          ++ 
Sbjct: 535  FQNELKQQQEREEELSTKVQVLIQQTNQLQQLINDSTNQAQVMRKLFLDPQNESAEADLP 594

Query: 607  NLAETRLKAISLLESQ-KFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLE 665
            N      KAI+L   + K DL Q    +Q+   E+ED     +Q        ++ ++ L 
Sbjct: 595  NQLMELNKAIALKFCKLKQDLEQNSKQIQEY--EIEDSKNSYNQQSLLIEQLQLTTIELN 652

Query: 666  EQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKL- 724
            +    +   + E AL+ + ++ + E L   +  L   + + +  LQN   +N DL  +  
Sbjct: 653  QAKQKIDNLQSENALLQKQMQTNSEFL-NNLNQLTLQQNEKIQNLQNLEIQNKDLIQQSI 711

Query: 725  -EKMSAEKISE---LLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICR 780
             EK   +++SE   +  + N + Q K+Q    +  +I +++  I N+ S++S+   +   
Sbjct: 712  SEKQINQQLSEQNIIFDQQNQDLQIKLQA---LQIEILKKEDLINNLSSKISQLNQQN-- 766

Query: 781  LEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEY-------TIQEDELVNRLAVLMDH 833
             +E + + E  ++ ++          QE Q + ++Y       T+Q   L   +  L D 
Sbjct: 767  -QEQVIINEQLQFQIKESIHNTQELQQENQISKTQYDQQNENLTMQNSTLEKEIIQLKDQ 825

Query: 834  DRVVEKQLLEIEHENKELQKKNQILLEE-NQNLQISLSDMQQHYNALVEKANRTD----L 888
              ++++Q+  +  + KEL+  N +  +E  Q  QI   D  Q     V++ ++T     L
Sbjct: 826  ITILDEQVNNLNQKIKELEILNSLKQDEIQQQDQIQQQDQIQQ-QVQVQEQDQTQQYDQL 884

Query: 889  AESESTKYQTQLRDLESNLKR--ITHEHQTLIVQKKK--EIEDLEIEFNTQIESAIRDKK 944
             +    + Q Q +D + N +   I   +Q + +Q ++  + + + +E N+Q+   +   K
Sbjct: 885  QQQVQLQDQVQQKDNQDNKQNEIIQQTYQEIGIQTEQLEQQQVINLELNSQLAEPLEINK 944

Query: 945  VLNEKYEKNIEYVT-QLEAQ---LQEYKNNIENLNMNVEELNKMN-LELI-DKHVQKQQT 998
              + K ++ IE +T QL  Q   LQ+ +N+I+ + +    L K + ++L+ +     Q  
Sbjct: 945  EQHSKLQQQIEELTIQLNQQTTALQQAQNDIDQMKIENTSLVKSHEMQLLREGEFTLQIE 1004

Query: 999  QSPDYTEQYINEINKLNALLK----QKDEEIIALNQKI---NNAQVSYMSMVSDY----E 1047
            Q  +  EQ  ++I +L   +K    Q   +I  L Q++   N+  +    ++  Y    E
Sbjct: 1005 QLIEINEQKSSKIEELETQIKESQLQYQNDIQELQQQLFTENDEWLKEKEIIQQYIDQLE 1064

Query: 1048 SKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIP 1107
             K  + T +++  ++E+Q + KQ        E LQI+  +     K+  E K  FE  I 
Sbjct: 1065 HKGLELTNQIKVKDDEIQNIQKQNQQLSDQLEGLQIVNEKAQQLEKQCLENKQKFEQQID 1124

Query: 1108 KTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQ--EEEEFIQERSVLQEQSAKL- 1164
            +     I    + +      +             LK Q  E+EE I+E+        +L 
Sbjct: 1125 EINLKNILKNNDFIKQ-IQQLQQQSQDDQVKLLELKKQLEEKEESIKEKDGKHAIEIQLI 1183

Query: 1165 -NTELQECYTKIIQLETLNTELTGHDVVNQEQIN------QLKSKLEQLNTENDNLLSTV 1217
             N  +     K   ++ L  E+  +  V  +Q N       +K  LEQ  +EN   +  +
Sbjct: 1184 TNNYVNRLKDKDDVIQNLQQEIQSYQQVELDQQNLIKFLENVKENLEQQKSENFEYIQEI 1243

Query: 1218 AELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQS 1277
                  I    +Q+  +I +L    +  +E + QK  HEL  +     + Y+Q L   QS
Sbjct: 1244 QLTNEKIIQQSEQQELQINQL---QVTIKELE-QKN-HELETEKINISNNYQQALIEAQS 1298

Query: 1278 --STQEETNKIV--TMEQVTSLQNKLQD 1301
               TQ+ +N+I+    E+V  L+ ++ D
Sbjct: 1299 LNQTQDNSNEIIEKMQEEVVLLKCRIGD 1326



 Score =  111 bits (268), Expect = 1e-22
 Identities = 191/919 (20%), Positives = 392/919 (42%), Gaps = 109/919 (11%)

Query: 702  DKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGI------DA 755
            D  D +N+ +N I E + L D  +K +   +   LA++   +   I +Q  I      D 
Sbjct: 99   DIADYLNQYKNDINEELLLQDCPDKKAKIHLKIHLAEVGEVDFDAINSQSSIVQEQTSDK 158

Query: 756  KIQERDLYIENIESELSKY----KSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQK 811
            K      + E  ES    +      +   L +S +  +    ++   + QLGS  Q++  
Sbjct: 159  KTGIFTPFKEAFESTKKYFGDSQSGQSPNLNKSFSKSQSNHPTVTDVSSQLGSPKQQQNS 218

Query: 812  AYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSD 871
              S   IQ D  +  L   ++  +++    +EI+ +N +LQ++ Q    + + L + L +
Sbjct: 219  NMSNQ-IQLD--LQHLHEELNQQKIL---YMEIKDQNNKLQQEVQTEKVKKEALVLQLQE 272

Query: 872  MQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIED---L 928
             ++  + +V++    ++ + +  +Y+ QL  ++S L++   +++ L    KK ++    L
Sbjct: 273  QRKQIDKMVDQ----NIYQEQICQYEQQLSQIQSQLRQAQKDNENLTQNYKKAMQKYNKL 328

Query: 929  EI---EFNT--------QIESAIRDKKVL--------NEKYEKNIEY---VTQLEAQLQE 966
             I   E NT        ++E   ++K  L        N+   +NI +   +TQ   QL +
Sbjct: 329  SINSEEQNTSSLKQRLQELEEICKNKDQLYSVLERSNNDSQHRNINFENQITQQNQQLLQ 388

Query: 967  YKNNIENLNMNV----EELNKMNLELIDKHVQK---QQTQS------PDYTEQYINE--- 1010
             KN ++  ++ +    E LN +NL+L++   Q    QQ +        + ++Q I +   
Sbjct: 389  LKNKLDEKDILIDSQKESLNNLNLQLLNLQNQNCSLQQNEKIHNEKIDELSKQIIQQQEQ 448

Query: 1011 INKLNALLKQKDEEIIAL-NQKINNAQVSYMSMVSDYESKLAQFTTKLENMEE----EMQ 1065
            IN+ +  +K++ E+ ++L NQ I N        +++  ++LA++ T+ E  ++    E++
Sbjct: 449  INQQSIEIKKQCEDHLSLDNQNIENLT----QQLNNKNNELAEYQTQCEQQKQKHQLEVE 504

Query: 1066 RVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDA 1125
             + KQ+   KQ  E++Q    + + +  E KE     E+   +     +S+ ++ +    
Sbjct: 505  ELLKQIQQQKQEKEQIQA---DLEQKYME-KEKNFQNELKQQQEREEELSTKVQVLIQQT 560

Query: 1126 NNVDXXXXXXXXXXXXL-KVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTE 1184
            N +             + K+  + +     + L  Q  +LN  +   + K+ Q    N++
Sbjct: 561  NQLQQLINDSTNQAQVMRKLFLDPQNESAEADLPNQLMELNKAIALKFCKLKQDLEQNSK 620

Query: 1185 LTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLA 1244
                  + + +I   K+   Q +   + L  T  EL  +    +D    E A L KQ   
Sbjct: 621  Q-----IQEYEIEDSKNSYNQQSLLIEQLQLTTIELNQA-KQKIDNLQSENALLQKQ--M 672

Query: 1245 QREADFQKTEHELRVQ----LSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQ 1300
            Q  ++F    ++L +Q    +   ++   Q  D +Q S  E+       EQ      + Q
Sbjct: 673  QTNSEFLNNLNQLTLQQNEKIQNLQNLEIQNKDLIQQSISEKQINQQLSEQNIIFDQQNQ 732

Query: 1301 DKEEHLRNLQE---KYADVINQIEILRSEIED---EKVAFXXXXXXXXXXXXXXXXDLRT 1354
            D +  L+ LQ    K  D+IN +    S++     E+V                  +L+ 
Sbjct: 733  DLQIKLQALQIEILKKEDLINNLSSKISQLNQQNQEQVIINEQLQFQIKESIHNTQELQQ 792

Query: 1355 ENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDS 1414
            ENQ  K   +Q   N+  +N+ L+K              +VN+   K+ EL     LK  
Sbjct: 793  ENQISKTQYDQQNENLTMQNSTLEKEIIQLKDQITILDEQVNNLNQKIKELEILNSLKQD 852

Query: 1415 EIYQK---------THEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLK 1465
            EI Q+           +  +    +  +++ ++QQ V+ + +++    +   +  I++  
Sbjct: 853  EIQQQDQIQQQDQIQQQVQVQEQDQTQQYDQLQQQ-VQLQDQVQQKDNQDNKQNEIIQQT 911

Query: 1466 MHENANHYETMQKESEIERVKLIEELNVKITESVSLNK-QVAELNKALEEEVAKTNEMQT 1524
              E     E ++++  I       ELN ++ E + +NK Q ++L + +EE   + N+  T
Sbjct: 912  YQEIGIQTEQLEQQQVINL-----ELNSQLAEPLEINKEQHSKLQQQIEELTIQLNQQTT 966

Query: 1525 ALENQEIEIVTLNDEITNL 1543
            AL+  + +I  +  E T+L
Sbjct: 967  ALQQAQNDIDQMKIENTSL 985



 Score = 97.9 bits (233), Expect = 2e-18
 Identities = 171/871 (19%), Positives = 354/871 (40%), Gaps = 64/871 (7%)

Query: 212  EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDV-RISSLEEANKLLEAARFEISLE 270
            E  KQ+     E  +    + K EK+++  D+E K + +  + +   K  +    E+S +
Sbjct: 493  EQQKQKHQLEVEELLKQIQQQKQEKEQIQADLEQKYMEKEKNFQNELKQQQEREEELSTK 552

Query: 271  HSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIEL 330
               L Q+  Q              + K  ++P   E  E +    L   N     K  +L
Sbjct: 553  VQVLIQQTNQLQQLINDSTNQAQVMRKLFLDPQ-NESAEADLPNQLMELNKAIALKFCKL 611

Query: 331  LEHLNCQIRQTNK-ELENKLATMGTESKAVSSPSKKGSPLISRK---SGRNTASKMKSPW 386
             + L    +Q  + E+E+   +   +S  +         L   K       + + +    
Sbjct: 612  KQDLEQNSKQIQEYEIEDSKNSYNQQSLLIEQLQLTTIELNQAKQKIDNLQSENALLQKQ 671

Query: 387  SQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKD 446
             Q +SE LN      + +NE  +    ++  NKDL+ +   ISEK             + 
Sbjct: 672  MQTNSEFLNNLNQLTLQQNEKIQNLQNLEIQNKDLIQQS--ISEKQ------INQQLSEQ 723

Query: 447  TLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLK 506
             +I   Q +  Q       I +    + +N ++    QL Q+ N E   +N + L  ++K
Sbjct: 724  NIIFDQQNQDLQIKLQALQIEILKKEDLINNLSSKISQLNQQ-NQEQVIIN-EQLQFQIK 781

Query: 507  SAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHH 566
             +     +L  E   +     +   N  ++   ++K I    ++ D   +I  L E++++
Sbjct: 782  ESIHNTQELQQENQISKTQYDQQNENLTMQNSTLEKEI---IQLKD---QITILDEQVNN 835

Query: 567  LSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDL 626
            L+QK+ ELE      Q  +   D  ++ + D  ++ ++++   +T+       + Q  D 
Sbjct: 836  LNQKIKELEILNSLKQDEIQQQD--QIQQQDQIQQQVQVQEQDQTQQYDQLQQQVQLQDQ 893

Query: 627  VQEL--------HILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKEL 678
            VQ+          I+QQ Y E+        QL+  QV +   +  L E ++       +L
Sbjct: 894  VQQKDNQDNKQNEIIQQTYQEIG---IQTEQLEQQQVINLELNSQLAEPLEINKEQHSKL 950

Query: 679  ALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAK 738
               IE L +   Q    ++  +ND + +  K++N           L +       E L +
Sbjct: 951  QQQIEELTIQLNQQTTALQQAQNDIDQM--KIENTSLVKSHEMQLLREGEFTLQIEQLIE 1008

Query: 739  INHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERK 798
            IN ++ SKI+    ++ +I+E  L          +Y++ I  L++ +    D     +  
Sbjct: 1009 INEQKSSKIEE---LETQIKESQL----------QYQNDIQELQQQLFTENDEWLKEKEI 1055

Query: 799  ADQLGSYLQEK-QKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQI 857
              Q    L+ K  +  ++  +++DE+ N    +   ++ +  QL  ++  N++ Q+  + 
Sbjct: 1056 IQQYIDQLEHKGLELTNQIKVKDDEIQN----IQKQNQQLSDQLEGLQIVNEKAQQLEKQ 1111

Query: 858  LLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTL 917
             LE  Q  +  + ++    N L        + + +      Q++ LE  LK+   E +  
Sbjct: 1112 CLENKQKFEQQIDEINLK-NILKNNDFIKQIQQLQQQSQDDQVKLLE--LKKQLEEKEES 1168

Query: 918  IVQKK-KEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNM 976
            I +K  K   ++++  N  + + ++DK  + +  ++ I+   Q+E   Q     +EN+  
Sbjct: 1169 IKEKDGKHAIEIQLITNNYV-NRLKDKDDVIQNLQQEIQSYQQVELDQQNLIKFLENVKE 1227

Query: 977  NVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIAL-NQKINNA 1035
            N+E+    N E I + +Q    +    +EQ   +IN+L   +K+ +++   L  +KIN +
Sbjct: 1228 NLEQQKSENFEYI-QEIQLTNEKIIQQSEQQELQINQLQVTIKELEQKNHELETEKINIS 1286

Query: 1036 QVSYMSMVSDYESKLAQFTTK--LENMEEEM 1064
                 +++        Q  +   +E M+EE+
Sbjct: 1287 NNYQQALIEAQSLNQTQDNSNEIIEKMQEEV 1317



 Score = 73.7 bits (173), Expect = 4e-11
 Identities = 159/841 (18%), Positives = 363/841 (43%), Gaps = 62/841 (7%)

Query: 152  KEKD--NALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXX 209
            KEK+  N L   Q + + + T +  L ++ N+  Q+I   N +T                
Sbjct: 531  KEKNFQNELKQQQEREEELSTKVQVLIQQTNQLQQLI---NDSTNQAQVMRKLFLDPQNE 587

Query: 210  XXE-DTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRIS--SLEEANKLLEAARFE 266
              E D   Q+ ++ +       + K + ++  K I+  ++  S  S  + + L+E  +  
Sbjct: 588  SAEADLPNQLMELNKAIALKFCKLKQDLEQNSKQIQEYEIEDSKNSYNQQSLLIEQLQLT 647

Query: 267  -ISLEHSKLA-QELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTEL 324
             I L  +K     L+                     + + ++  +I+   +LEI N   +
Sbjct: 648  TIELNQAKQKIDNLQSENALLQKQMQTNSEFLNNLNQLTLQQNEKIQNLQNLEIQNKDLI 707

Query: 325  TKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKS 384
             + I   + +N Q+ + N   + +   +  + +A+     K   LI+  S + +    ++
Sbjct: 708  QQSISE-KQINQQLSEQNIIFDQQNQDLQIKLQALQIEILKKEDLINNLSSKISQLNQQN 766

Query: 385  PWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXG 444
                + +E L     + I+  +  + E  I     D    E +  +  T           
Sbjct: 767  QEQVIINEQLQFQIKESIHNTQELQQENQISKTQYDQ-QNENLTMQNSTLEKEIIQLKDQ 825

Query: 445  KDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVK-DLIE 503
               L  Q+   +Q+  E   L  +  +     +  + Q+Q++Q++  + +D   + D ++
Sbjct: 826  ITILDEQVNNLNQKIKELEILNSLKQDEIQQQDQIQQQDQIQQQVQVQEQDQTQQYDQLQ 885

Query: 504  KLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQM-QKTIDNFSKVSDSNKEIVRLTE 562
            +    ++Q+ Q +++ +  N+ + +      ++ +Q+ Q+ + N  +++    E + + +
Sbjct: 886  QQVQLQDQVQQKDNQDNKQNEIIQQTYQEIGIQTEQLEQQQVINL-ELNSQLAEPLEINK 944

Query: 563  ELHH-LSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLES 621
            E H  L Q++ EL      +QL+     + +  ++D+ +  IE  +L ++    + LL  
Sbjct: 945  EQHSKLQQQIEEL-----TIQLNQ-QTTALQQAQNDIDQMKIENTSLVKSH--EMQLLRE 996

Query: 622  QKFDLVQE--LHILQQKYDEVEDKLADI--SQLQSDQVCSEIKSVHLEEQIDALSASKKE 677
             +F L  E  + I +QK  ++E+    I  SQLQ      E++     E  + L   K+ 
Sbjct: 997  GEFTLQIEQLIEINEQKSSKIEELETQIKESQLQYQNDIQELQQQLFTENDEWLK-EKEI 1055

Query: 678  LALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLA 737
            +   I+ L+    +L   IK     K+D   ++QN  ++N  L+D+LE +    ++E   
Sbjct: 1056 IQQYIDQLEHKGLELTNQIKV----KDD---EIQNIQKQNQQLSDQLEGLQI--VNE--- 1103

Query: 738  KINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLER 797
            K    E+  ++ +   + +I E +L  +NI    + +  +I +L++     + +   L++
Sbjct: 1104 KAQQLEKQCLENKQKFEQQIDEINL--KNILKN-NDFIKQIQQLQQQSQDDQVKLLELKK 1160

Query: 798  KADQLGSYLQEKQKAYS-EYTIQEDELVNRLAVLMDHDRVVEKQLLEIE-HENKELQKKN 855
            + ++    ++EK   ++ E  +  +  VNRL    D D V++    EI+ ++  EL ++N
Sbjct: 1161 QLEEKEESIKEKDGKHAIEIQLITNNYVNRLK---DKDDVIQNLQQEIQSYQQVELDQQN 1217

Query: 856  QILLEEN--QNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHE 913
             I   EN  +NL+   S+  ++    ++  N   + +SE  + + Q+  L+  +K +   
Sbjct: 1218 LIKFLENVKENLEQQKSENFEYIQE-IQLTNEKIIQQSE--QQELQINQLQVTIKELE-- 1272

Query: 914  HQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIEN 973
                  QK  E+E  +I  +   + A+ + + LN+  + + E + +++ ++   K  I +
Sbjct: 1273 ------QKNHELETEKINISNNYQQALIEAQSLNQTQDNSNEIIEKMQEEVVLLKCRIGD 1326

Query: 974  L 974
            +
Sbjct: 1327 M 1327



 Score = 69.7 bits (163), Expect = 6e-10
 Identities = 131/742 (17%), Positives = 308/742 (41%), Gaps = 62/742 (8%)

Query: 887  DLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDL--EIEFNTQ-IESAIRDK 943
            D    +S          +SN   +T     L   K+++  ++  +I+ + Q +   +  +
Sbjct: 179  DSQSGQSPNLNKSFSKSQSNHPTVTDVSSQLGSPKQQQNSNMSNQIQLDLQHLHEELNQQ 238

Query: 944  KVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDY 1003
            K+L   Y +  +   +L+ ++Q  K   E L + ++E  K   +++D+++ ++Q      
Sbjct: 239  KIL---YMEIKDQNNKLQQEVQTEKVKKEALVLQLQEQRKQIDKMVDQNIYQEQIC---- 291

Query: 1004 TEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSM-VSDYESKLAQFTTKLENMEE 1062
              QY  +++++ + L+Q  ++   L Q    A   Y  + ++  E   +    +L+ +EE
Sbjct: 292  --QYEQQLSQIQSQLRQAQKDNENLTQNYKKAMQKYNKLSINSEEQNTSSLKQRLQELEE 349

Query: 1063 ------EMQRVSKQLLDSKQH-NEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIIS 1115
                  ++  V ++  +  QH N   +  + +Q+ Q+ +LK      ++ I   +  + +
Sbjct: 350  ICKNKDQLYSVLERSNNDSQHRNINFENQITQQNQQLLQLKNKLDEKDILIDSQKESLNN 409

Query: 1116 STIEPMSDDANNVDXXXXXXXXXXXXLKVQE-EEEFIQERSVLQEQSAKLNTELQECYTK 1174
              ++ ++    N               K+ E  ++ IQ++  + +QS ++  + ++  + 
Sbjct: 410  LNLQLLNLQNQNCSLQQNEKIHNE---KIDELSKQIIQQQEQINQQSIEIKKQCEDHLSL 466

Query: 1175 IIQ-LETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSS---ISSAVDQ 1230
              Q +E L  +L   +    E   Q + + ++   E + LL  + + +     I + ++Q
Sbjct: 467  DNQNIENLTQQLNNKNNELAEYQTQCEQQKQKHQLEVEELLKQIQQQKQEKEQIQADLEQ 526

Query: 1231 RGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEET--NKIVT 1288
            +  E  + ++  L Q+    Q+ E EL  ++     +  QL   +  ST +     K+  
Sbjct: 527  KYMEKEKNFQNELKQQ----QEREEELSTKVQVLIQQTNQLQQLINDSTNQAQVMRKLFL 582

Query: 1289 MEQVTS----LQNKLQD--KEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXX 1342
              Q  S    L N+L +  K   L+  + K     N  +I   EIED K ++        
Sbjct: 583  DPQNESAEADLPNQLMELNKAIALKFCKLKQDLEQNSKQIQEYEIEDSKNSYNQQSLLIE 642

Query: 1343 XXXXXXXXDLRTENQSYKQMQEQSIL--NINEENAQLKKSSXXXXXXXXXXXXRVNDAEA 1400
                    +L    Q    +Q ++ L     + N++   +              + + E 
Sbjct: 643  QLQLTTI-ELNQAKQKIDNLQSENALLQKQMQTNSEFLNNLNQLTLQQNEKIQNLQNLEI 701

Query: 1401 KVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQL-VEYEKR----------IE 1449
            +  +L  Q  + + +I Q+  E  I   Q+N + +   Q L +E  K+          I 
Sbjct: 702  QNKDLIQQ-SISEKQINQQLSEQNIIFDQQNQDLQIKLQALQIEILKKEDLINNLSSKIS 760

Query: 1450 DLTYEKESELAI---LRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVA 1506
             L  + + ++ I   L+ ++ E+ ++ + +Q+E++I + +  ++      ++ +L K++ 
Sbjct: 761  QLNQQNQEQVIINEQLQFQIKESIHNTQELQQENQISKTQYDQQNENLTMQNSTLEKEII 820

Query: 1507 ELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQ 1566
            +L   +     + N +   ++  EI      DEI   Q+ ++    +IQ+ V      + 
Sbjct: 821  QLKDQITILDEQVNNLNQKIKELEILNSLKQDEIQQ-QDQIQ-QQDQIQQQVQVQEQDQT 878

Query: 1567 GRDEQLDNTMNKELLDAVPRAE 1588
             + +QL   +  +L D V + +
Sbjct: 879  QQYDQLQQQV--QLQDQVQQKD 898


>UniRef50_Q4RT41 Cluster: Chromosome 12 SCAF14999, whole genome
            shotgun sequence; n=4; Eumetazoa|Rep: Chromosome 12
            SCAF14999, whole genome shotgun sequence - Tetraodon
            nigroviridis (Green puffer)
          Length = 1488

 Score =  137 bits (331), Expect = 3e-30
 Identities = 267/1364 (19%), Positives = 552/1364 (40%), Gaps = 106/1364 (7%)

Query: 240  LKDIESKD-VRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQ 298
            +K++E ++ V     E+ ++  +    E+    S++AQ  E+               + Q
Sbjct: 15   VKELEERETVLTQQTEDKDRETKEQMAEMVALRSQVAQNNEEMVTLKKQLEVVQSQGSDQ 74

Query: 299  S---IEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTE 355
                +E SC+ ++  +E  SL+ +      +K  L + L C  +  ++  E K  +  T 
Sbjct: 75   GAKVVELSCQLESGQQEVLSLQKSLAASKQEKEALDKELACLKQNLSESTEEKTKSAKTM 134

Query: 356  SKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQ 415
             +A+   SKK     S  +   T        SQL+        ++K+ K     LE  ++
Sbjct: 135  QEALDQLSKKEEEYTSLTAESETLR------SQLAG------LERKL-KTAAEALEQHVK 181

Query: 416  SLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVG-TNTED 474
               K   D   ++  K +           +D +  + +LE  Q         V   N + 
Sbjct: 182  DKRKLETDMSEMM--KQSGDSSAQLTKMNQDLIEKERKLEDFQSQLAEEKNKVALLNEQA 239

Query: 475  VNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQ---LNDEIDAANKNMIKVKS 531
              E +    +LK+    E     V DL EK++S E+ + +   L +E+ A+ ++ +   S
Sbjct: 240  EQEKSHKDRELKE--TKETHQSQVNDLQEKIRSLEKAVKEGETLAEELKASQQSSVSQAS 297

Query: 532  N-HKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDS 590
              H  +++ +Q  +D   +   S+K       +   L + V+EL+  K   Q    + DS
Sbjct: 298  ELHAKEVELLQNQVDKLEQELSSSK------VKSEALEKSVSELQAYKEQAQCLSAELDS 351

Query: 591  GRMIESDVYKKMIEMENL-AETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADIS- 648
             + ++ +   + +E ++L  E   K    + ++K  L +EL  +Q ++  +E     +S 
Sbjct: 352  YK-LDVEHLSRNLEKQSLDLENMCKESDCVRAEKGKLEKELSEVQSRFSALETAHGALSG 410

Query: 649  QLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMN 708
            Q +  Q+  E  S + EE +  +  S +E       L    E+L   +++++   E   N
Sbjct: 411  QKEELQMVREELSKNQEELLAKMKCSDEER----NQLNKQLEKLREDLQEMQRQNE---N 463

Query: 709  KLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSK---IQTQFGIDAKIQERDLYIE 765
              Q   Q+ ++ T+ L+K +AE    LL +    +Q++    Q     DA   ER    +
Sbjct: 464  LKQINDQQKIE-TEDLQKQNAESNDSLLKQQEQLQQAEGKYRQLLHDYDAACHER----K 518

Query: 766  NIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVN 825
             +E EL + +S++    +++ +  D   + ++  D   + LQ K K+ +   +++++L  
Sbjct: 519  RLEGELGESRSKLTCERDNVVLERDSARNAKKALDAKNAELQAKLKSLN---LEKEDLTL 575

Query: 826  RLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLS----DMQQHYNALVE 881
            +   L      + K+  E+  E     +  + L    + LQ  LS    D++       E
Sbjct: 576  KNTQLQALTEALTKEKEEMSSEISTAVRDKKSLEAAKEELQNKLSATKKDLESSIRECEE 635

Query: 882  -KANRTDLAES-ESTKYQTQLRDLESNLKRITHEHQTLIVQKK--KEIEDLEIEFNTQIE 937
             +A++  LA+  E  K  +Q+ D E  +  +  + + L  Q++   E E+L+ E     E
Sbjct: 636  LRASKVSLAQMLEEFKKTSQVTDSE-RMNLLQQKEELLASQRRACSEREELQGEIGEVQE 694

Query: 938  SAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQ 997
                  + L+E   K+ + ++  EA+ + +        M +    K  + L +  +++Q+
Sbjct: 695  KLRAATEQLSELRGKHTDALSSFEAEKKAFSLQTSEAEMALHVSRKEKMSL-ESALEQQK 753

Query: 998  TQSPDYTEQYINEINKLNALLKQKDE-----EIIALNQKINNAQVSYMSMV-SDYESKLA 1051
                   E+     N+L   + +KD      + +A + +    Q+   S   +D+  + +
Sbjct: 754  MGYECLLEEKGELENRLTDTVSEKDALSCECDRLARDLQTLKDQLDRSSRENADFVQEKS 813

Query: 1052 QFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEG 1111
              T KLE            +   ++    LQ  +++    ++ L++ K   E    K + 
Sbjct: 814  DLTAKLEESVRSKAAADADVSSLEKEKATLQGELQKHKSDLEALEKNKRELEQEREKLKT 873

Query: 1112 MIISST------IEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLN 1165
                ST      I+ + +D   +             ++ +E++E ++E   L+ Q+  L+
Sbjct: 874  EFKESTSELAQQIDSLKNDCQRLQSLRTESDAGLQAVQ-KEKQEMLEESQELRRQAEALS 932

Query: 1166 TELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSIS 1225
             + +   T++    +  T+   H      Q+ +L+ ++ Q+  EN  L S +  L   + 
Sbjct: 933  EDKRLLETRLQAESSERTKAASHQDQLARQLEELQKEMVQVTQENQELSSNLRNLDEQMR 992

Query: 1226 SAVDQRGFEIAELWKQHLAQREADF-QKTE---------HELRVQLSAFESKYEQLLDSV 1275
            ++V  R     E  K+ L QRE D  Q+ E          E   Q+++  ++ E LLD  
Sbjct: 993  TSVMDR-----EALKEQLKQREQDIGQRAEEKEGLLVQLQEREKQVASLTTERESLLDGR 1047

Query: 1276 QSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDE---KV 1332
                 + +    + E   + ++ +  + E  R LQEK    +  ++  + ++E++    V
Sbjct: 1048 SKLEMDVSALRSSQESWLAERSTVLAEVEESRCLQEKLEADMKVLQTAKEQLEEQHKSAV 1107

Query: 1333 AFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXX 1392
                              DL  + ++ +  ++++   I +   QLK +S           
Sbjct: 1108 EEISASALAKAESRSSIADLTAQKKTLQAERDEAAQQIRQLQIQLKNASAKQVEMKELRA 1167

Query: 1393 XRV---NDAEAKVLELTHQLELKDS---EIYQ-KTHE--YTITLTQRNDEFENVRQQLVE 1443
                   D  A   +L  + +   S   EI   KT +   T +L    DE + + Q+L  
Sbjct: 1168 ENSKYHEDLSASKEQLCTETQRTKSLCQEIEDLKTADSAKTQSLQALKDENDKLTQELDI 1227

Query: 1444 YEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEE---LNVKITESVS 1500
                  +LT  K++    LR +  E  N  E  QK +   R +   E   L   + ++ +
Sbjct: 1228 AHGGQSELTKVKQAYFLKLRKENSELQNQLEESQKSASTFREQSDGEKAALQQSMRKNSA 1287

Query: 1501 LNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQ 1544
            L  +  +L + L  EVA+ +    A+ + +  +  L  +   L+
Sbjct: 1288 LIAEKEQLVQKLRSEVAELHSRGAAVPSLQGAVQALEQDKKELE 1331



 Score = 89.0 bits (211), Expect = 9e-16
 Identities = 153/793 (19%), Positives = 318/793 (40%), Gaps = 50/793 (6%)

Query: 765  ENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELV 824
            E+ + E  +  + +  L   +A   +   +L+++ + + S   ++     E + Q  E  
Sbjct: 30   EDKDRETKEQMAEMVALRSQVAQNNEEMVTLKKQLEVVQSQGSDQGAKVVELSCQL-ESG 88

Query: 825  NRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKAN 884
             +  + +       KQ  E E  +KEL    Q L E  +    S   MQ+  + L +K  
Sbjct: 89   QQEVLSLQKSLAASKQ--EKEALDKELACLKQNLSESTEEKTKSAKTMQEALDQLSKKEE 146

Query: 885  RTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKK 944
                  +ES   ++QL  LE  LK      +  +  K+K   D+        +S+ +  K
Sbjct: 147  EYTSLTAESETLRSQLAGLERKLKTAAEALEQHVKDKRKLETDMSEMMKQSGDSSAQLTK 206

Query: 945  VLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYT 1004
            +  +  EK  + +   ++QL E KN +  LN   E+           H  ++  ++ +  
Sbjct: 207  MNQDLIEKERK-LEDFQSQLAEEKNKVALLNEQAEQEKS--------HKDRELKETKETH 257

Query: 1005 EQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEM 1064
            +  +N++ +    L++  +E   L +++  +Q S +S  S+  +K      ++E ++ ++
Sbjct: 258  QSQVNDLQEKIRSLEKAVKEGETLAEELKASQQSSVSQASELHAK------EVELLQNQV 311

Query: 1065 QRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDD 1124
             ++ ++L  SK  +E L+  V E     KE  +  L+ E++  K +   +S  +E  S D
Sbjct: 312  DKLEQELSSSKVKSEALEKSVSELQ-AYKEQAQC-LSAELDSYKLDVEHLSRNLEKQSLD 369

Query: 1125 ANNVDXXXXXXXXXXXXLKVQEEEEFIQER-SVLQEQSAKLNTELQECYTKIIQLETLNT 1183
              N+              K+++E   +Q R S L+     L+ + +E      +L     
Sbjct: 370  LENMCKESDCVRAEKG--KLEKELSEVQSRFSALETAHGALSGQKEELQMVREELSKNQE 427

Query: 1184 ELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHL 1243
            EL      + E+ NQL  +LE+L  +    L  +     ++    DQ+  E  +L KQ+ 
Sbjct: 428  ELLAKMKCSDEERNQLNKQLEKLRED----LQEMQRQNENLKQINDQQKIETEDLQKQNA 483

Query: 1244 AQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKE 1303
               ++  ++ E     QL   E KY QLL    ++  E         ++   ++KL  + 
Sbjct: 484  ESNDSLLKQQE-----QLQQAEGKYRQLLHDYDAACHERKR---LEGELGESRSKLTCER 535

Query: 1304 EHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQ 1363
            +++   ++   +    ++   +E++    A                  L+   ++  + +
Sbjct: 536  DNVVLERDSARNAKKALDAKNAELQ----AKLKSLNLEKEDLTLKNTQLQALTEALTKEK 591

Query: 1364 EQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEY 1423
            E+    I+      K                  D E+ + E   +L      + Q   E+
Sbjct: 592  EEMSSEISTAVRDKKSLEAAKEELQNKLSATKKDLESSIREC-EELRASKVSLAQMLEEF 650

Query: 1424 TITLTQRNDEFENVRQQ---LVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKES 1480
              T    + E  N+ QQ   L+  ++R      E + E+  ++ K+          ++ S
Sbjct: 651  KKTSQVTDSERMNLLQQKEELLASQRRACSEREELQGEIGEVQEKLRA------ATEQLS 704

Query: 1481 EIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEI 1540
            E+ R K  + L+    E  + + Q +E   AL     +   +++ALE Q++    L +E 
Sbjct: 705  EL-RGKHTDALSSFEAEKKAFSLQTSEAEMALHVSRKEKMSLESALEQQKMGYECLLEEK 763

Query: 1541 TNLQNMVRASSSK 1553
              L+N +  + S+
Sbjct: 764  GELENRLTDTVSE 776



 Score = 85.4 bits (202), Expect = 1e-14
 Identities = 166/898 (18%), Positives = 359/898 (39%), Gaps = 49/898 (5%)

Query: 228  MEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXX 287
            +E E  + + +L  + ++  +   S   A K L+A   E+  +   L  E E        
Sbjct: 520  LEGELGESRSKLTCERDNVVLERDSARNAKKALDAKNAELQAKLKSLNLEKEDLTLKNTQ 579

Query: 288  XXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELL-EHLNCQIRQTNKELE 346
                   L K+  E S E  T + +K SLE A   EL  K+    + L   IR+  +   
Sbjct: 580  LQALTEALTKEKEEMSSEISTAVRDKKSLEAAK-EELQNKLSATKKDLESSIRECEELRA 638

Query: 347  NK--LATMGTESKAVSSPSKKGSPLISRKSGRNTASKMK--SPWSQLSSETLNQDTDKKI 402
            +K  LA M  E K  S  +      + ++     AS+ +  S   +L  E        + 
Sbjct: 639  SKVSLAQMLEEFKKTSQVTDSERMNLLQQKEELLASQRRACSEREELQGEIGEVQEKLRA 698

Query: 403  NKNEIAKLE-MVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHME 461
               ++++L      +L+    +K+       T           K+ +  +  LE Q+   
Sbjct: 699  ATEQLSELRGKHTDALSSFEAEKK--AFSLQTSEAEMALHVSRKEKMSLESALEQQKMGY 756

Query: 462  GPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDV-NVKDLIEKLKSAEEQITQLNDEID 520
               L   G     + +    ++ L  E +   +D+  +KD +++         Q   ++ 
Sbjct: 757  ECLLEEKGELENRLTDTVSEKDALSCECDRLARDLQTLKDQLDRSSRENADFVQEKSDLT 816

Query: 521  AANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGN 580
            A  +  ++ K+     +  ++K      + +    E+ +   +L  L +   ELE+E+  
Sbjct: 817  AKLEESVRSKAAADADVSSLEK------EKATLQGELQKHKSDLEALEKNKRELEQEREK 870

Query: 581  LQLHLVDYDSGRMIESDVYKKMIE-MENLAETRLKAISLLESQKFDLVQELHILQQKYDE 639
            L+    +  S    + D  K   + +++L       +  ++ +K ++++E   L+++ + 
Sbjct: 871  LKTEFKESTSELAQQIDSLKNDCQRLQSLRTESDAGLQAVQKEKQEMLEESQELRRQAEA 930

Query: 640  V-EDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKD 698
            + EDK    ++LQ++       + H ++    L   +KE+  V +    + ++L   +++
Sbjct: 931  LSEDKRLLETRLQAESSERTKAASHQDQLARQLEELQKEMVQVTQ----ENQELSSNLRN 986

Query: 699  L-ENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKI 757
            L E  +  +M++    ++E +   ++     AE+   LL ++   E+         ++ +
Sbjct: 987  LDEQMRTSVMDR--EALKEQLKQREQDIGQRAEEKEGLLVQLQEREKQVASLTTERESLL 1044

Query: 758  QERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYT 817
              R     ++ +  S  +S +      +A +E+ R  L+ K +     LQ  ++   E  
Sbjct: 1045 DGRSKLEMDVSALRSSQESWLAERSTVLAEVEESR-CLQEKLEADMKVLQTAKEQLEEQH 1103

Query: 818  IQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYN 877
                E ++  A+     R     + ++  + K LQ +     ++ + LQI L       N
Sbjct: 1104 KSAVEEISASALAKAESR---SSIADLTAQKKTLQAERDEAAQQIRQLQIQLK------N 1154

Query: 878  ALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIE 937
            A  ++    +L  +E++KY   L   +  L   T   ++L     +EIEDL+   + + +
Sbjct: 1155 ASAKQVEMKEL-RAENSKYHEDLSASKEQLCTETQRTKSLC----QEIEDLKTADSAKTQ 1209

Query: 938  SAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMN-LELIDKHVQKQ 996
            S ++  K  N+K  + ++     +++L + K     L +  E     N LE   K     
Sbjct: 1210 S-LQALKDENDKLTQELDIAHGGQSELTKVK-QAYFLKLRKENSELQNQLEESQKSASTF 1267

Query: 997  QTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTK 1056
            + QS          + K +AL+ +K++ +  L  ++     S  + V   +  +      
Sbjct: 1268 REQSDGEKAALQQSMRKNSALIAEKEQLVQKLRSEVAELH-SRGAAVPSLQGAVQALEQD 1326

Query: 1057 LENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMII 1114
             + +EE  QR+ ++L  +K       + +   D  + +L+E K T E  I     +I+
Sbjct: 1327 KKELEERAQRLEEELAAAKN-----TLSLPSGDAVLDQLREDKETAESQIQFLNSVIV 1379



 Score = 55.6 bits (128), Expect = 1e-05
 Identities = 92/508 (18%), Positives = 194/508 (38%), Gaps = 21/508 (4%)

Query: 1060 MEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIE 1119
            ME+ + ++    L  K+  E   +L ++ +D+ +E KE     EM   +++    +  + 
Sbjct: 1    MEDVLGKLHAAELRVKELEERETVLTQQTEDKDRETKEQMA--EMVALRSQVAQNNEEMV 58

Query: 1120 PMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLE 1179
             +      V             L  Q E    QE   LQ+  A    E +    ++  L+
Sbjct: 59   TLKKQLEVVQSQGSDQGAKVVELSCQLESGQ-QEVLSLQKSLAASKQEKEALDKELACLK 117

Query: 1180 TLNTELTGHDVVN----QEQINQLKSKLEQ---LNTENDNLLSTVAELRSSISSAVDQRG 1232
               +E T     +    QE ++QL  K E+   L  E++ L S +A L   + +A +   
Sbjct: 118  QNLSESTEEKTKSAKTMQEALDQLSKKEEEYTSLTAESETLRSQLAGLERKLKTAAEALE 177

Query: 1233 FEIAELWKQHLAQREADFQKTEHELRVQLSAFES---KYEQLLDSVQSSTQEETNKIVTM 1289
              + +  K+ L    ++  K   +   QL+       + E+ L+  QS   EE NK+  +
Sbjct: 178  QHVKD--KRKLETDMSEMMKQSGDSSAQLTKMNQDLIEKERKLEDFQSQLAEEKNKVALL 235

Query: 1290 EQVTSLQNKLQDKEEHLRNLQEKYADVINQI-EILRSEIEDEKVAFXXXXXXXXXXXXXX 1348
             +    +   +D+E  L+  +E +   +N + E +RS  +  K                 
Sbjct: 236  NEQAEQEKSHKDRE--LKETKETHQSQVNDLQEKIRSLEKAVKEGETLAEELKASQQSSV 293

Query: 1349 XXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQ 1408
                    +  + +Q Q +  + +E +  K  S                A+    EL   
Sbjct: 294  SQASELHAKEVELLQNQ-VDKLEQELSSSKVKSEALEKSVSELQAYKEQAQCLSAELD-S 351

Query: 1409 LELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHE 1468
             +L    + +   + ++ L     E + VR +  + EK + ++   + S L      +  
Sbjct: 352  YKLDVEHLSRNLEKQSLDLENMCKESDCVRAEKGKLEKELSEVQ-SRFSALETAHGALSG 410

Query: 1469 NANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALEN 1528
                 + +++E    + +L+ ++     E   LNKQ+ +L + L+E   +   ++   + 
Sbjct: 411  QKEELQMVREELSKNQEELLAKMKCSDEERNQLNKQLEKLREDLQEMQRQNENLKQINDQ 470

Query: 1529 QEIEIVTLNDEITNLQNMVRASSSKIQK 1556
            Q+IE   L  +     + +     ++Q+
Sbjct: 471  QKIETEDLQKQNAESNDSLLKQQEQLQQ 498



 Score = 54.0 bits (124), Expect = 3e-05
 Identities = 116/576 (20%), Positives = 228/576 (39%), Gaps = 43/576 (7%)

Query: 174  DLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWK 233
            DL+     K ++ + + K  T                  D ++  +   E+   ++A  K
Sbjct: 853  DLEALEKNKRELEQEREKLKTEFKESTSELAQQIDSLKNDCQRLQSLRTESDAGLQAVQK 912

Query: 234  DEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXX 293
             EKQ +L++ +    +  +L E  +LLE      S E +K A   +Q             
Sbjct: 913  -EKQEMLEESQELRRQAEALSEDKRLLETRLQAESSERTKAASHQDQLARQLEELQKEMV 971

Query: 294  XLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMG 353
             + +++ E S   +  ++E+    + +   L ++++  E     I Q  +E E  L  + 
Sbjct: 972  QVTQENQELSSNLR-NLDEQMRTSVMDREALKEQLKQREQ---DIGQRAEEKEGLLVQLQ 1027

Query: 354  TESKAVSS-PSKKGSPLISRKSGRNTASKMKS---PWSQLSSETLNQDTDKKINKNEIAK 409
               K V+S  +++ S L  R       S ++S    W    S  L +  + +  + ++  
Sbjct: 1028 EREKQVASLTTERESLLDGRSKLEMDVSALRSSQESWLAERSTVLAEVEESRCLQEKLEA 1087

Query: 410  LEMVIQSLNKDLVDK-EYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHV 468
               V+Q+  + L ++ +  + E                 L AQ +    +  E    I  
Sbjct: 1088 DMKVLQTAKEQLEEQHKSAVEEISASALAKAESRSSIADLTAQKKTLQAERDEAAQQIR- 1146

Query: 469  GTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIK 528
                +  N  AK Q ++K     E++  N K   E L +++EQ+        +  + +  
Sbjct: 1147 QLQIQLKNASAK-QVEMK-----ELRAENSK-YHEDLSASKEQLCTETQRTKSLCQEIED 1199

Query: 529  VKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQK-VAELEEEKGNLQLHLVD 587
            +K+    K + +Q   D   K++           EL  + Q    +L +E   LQ  L +
Sbjct: 1200 LKTADSAKTQSLQALKDENDKLTQELDIAHGGQSELTKVKQAYFLKLRKENSELQNQLEE 1259

Query: 588  YDSGRMIESDVYKKMIEMENLA-ETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLAD 646
                    +  +++  + E  A +  ++  S L ++K  LVQ+   L+ +  E+  + A 
Sbjct: 1260 SQK----SASTFREQSDGEKAALQQSMRKNSALIAEKEQLVQK---LRSEVAELHSRGAA 1312

Query: 647  ISQLQSDQVCSEIKSVHLEEQI----DALSASKKELAL-----VIENLKLDKEQLYGTIK 697
            +  LQ      E     LEE+     + L+A+K  L+L     V++ L+ DKE     I+
Sbjct: 1313 VPSLQGAVQALEQDKKELEERAQRLEEELAAAKNTLSLPSGDAVLDQLREDKETAESQIQ 1372

Query: 698  DLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKIS 733
             L +   D+  K       N +L +KLEK++A  ++
Sbjct: 1373 FLNSVIVDLQRK-------NEELKEKLEKVAAAALN 1401


>UniRef50_A0DQH1 Cluster: Chromosome undetermined scaffold_6, whole
            genome shotgun sequence; n=4; Paramecium tetraurelia|Rep:
            Chromosome undetermined scaffold_6, whole genome shotgun
            sequence - Paramecium tetraurelia
          Length = 1075

 Score =  137 bits (331), Expect = 3e-30
 Identities = 217/1058 (20%), Positives = 462/1058 (43%), Gaps = 93/1058 (8%)

Query: 546  NFSKVSDSNK--EIVRLTEELHHLSQKVAELE---EEKGNLQLHLV-DYDSGRMIESDVY 599
            N+ K  D +   E+ +  ++   L  ++A+ E   E K  LQ  ++   +  +  + D  
Sbjct: 54   NYDKEVDESARDELEQWKKKYFSLEARLAKYEIDNEIKDELQSRILGSQEDVKKFQIDFT 113

Query: 600  KKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEI 659
            K   +++N      K I  +E+QK  L Q++ + + K   V ++   ISQL   Q C E 
Sbjct: 114  KAQADLDNQKSEMNKLI--IENQKL-LNQQVEVERLK-KLVAEREDTISQLL--QKCKEY 167

Query: 660  KSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKD--LENDKEDIMNKLQNYIQEN 717
                 +EQ   L A ++ L   + N    KE +  T K   +END     NK Q  I E 
Sbjct: 168  -----QEQFQELEAFQQALQ-DMHNQNQGKELMIETWKQKYIEND-----NKKQKEIDEL 216

Query: 718  MDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFG-IDAKIQERDLYIENIESELSKYKS 776
                 +      + + +   +   E Q++++ Q   + A +++ D +     +   +++ 
Sbjct: 217  KSKLAEFNPAEVQNLKDQFQRERQESQNQLKKQQSDLAAALKQLDQWKIKYNNLDLQHQQ 276

Query: 777  RICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRV 836
                 +ESIA +E       + + Q+    ++KQK   E    + +L     ++ + DR+
Sbjct: 277  LSSAQKESIARVETLTQEQNKLSTQIHQLNEDKQKLQIELEQTKGQLKLHQGLIGELDRI 336

Query: 837  VEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKY 896
              K+LL    ++ ELQ+    +L+++Q   I L++ +   + L +K     L + E+ + 
Sbjct: 337  --KKLLS--DKSAELQQ----MLQQSQQKDIDLNNAELTISELNQKIKSLSLLQQENQRL 388

Query: 897  QTQLRDLESNLKRITHEHQTLI--VQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNI 954
            Q ++ +     +++  E+  L+  + K K +E  + +  +++     + + L  + ++  
Sbjct: 389  QHEIDESHRENEKLAQENSQLLKDIDKFKLLEQEKQQLESKVSMLASEIERLKVQLKQKN 448

Query: 955  EYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKL 1014
            E + +   Q ++ KN  E L   +E+L   N +L+ +  QK +    +  EQ + E+N L
Sbjct: 449  EKILE---QQEDLKNLQEQLG-EIEQLENQNQQLLKELEQKDKII--EELEQKLQELNVL 502

Query: 1015 NALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQ--RVSKQLL 1072
               L   + +I  L  K+  A +S  S    Y +   Q T +L+N EE++    + K+ L
Sbjct: 503  EQKLADANNKIYDLENKV--AMLSAESQRLRYLND--QKTEQLKNAEEQLSDLNILKEKL 558

Query: 1073 DSKQHNEELQILVREQ-DDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXX 1131
               Q+  + Q  V +   D++++L+        NI + +  +     + +    +N +  
Sbjct: 559  SQLQNKYDAQQQVNQNYQDELEKLRGQSNQANTNIAELKRQLEEQKAQDIIHKQSNSESV 618

Query: 1132 XXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQL-ETLNTELT--GH 1188
                      L  Q+  + + E ++  E+   L  +LQ   T + Q  + LN  +     
Sbjct: 619  IAELQQQLSSL--QQSYKKVSESNLANEEDPTL--DLQNRLTLLKQENQRLNQTIQQKNQ 674

Query: 1189 DVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQ-----RGFEIAELWKQHL 1243
            +V+N +Q NQ    L+Q   E D+L   + EL  S +   +Q     +G +  E   Q  
Sbjct: 675  EVLNHQQQNQ---NLQQELLELDSLKVQIKELHESNTVLQEQLQNEAKGRQELEQRIQQT 731

Query: 1244 AQREADFQKTEHELRVQLSAFESKYEQL--LDSVQSSTQEETNKIVTME----QVTSLQN 1297
               + D Q     L   +   + K +++  +D ++   QE   ++  M+    ++ SL++
Sbjct: 732  ESEKYDLQSKCAMLSTHIEGMKYKLDKMENVDDLKKRIQELEGQLAEMQALELEIESLKD 791

Query: 1298 KLQDKEEHLRNLQEKYADV---INQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRT 1354
            ++ + E+ L+  ++K+  +     Q+++ + ++E++                    ++  
Sbjct: 792  RIAELEKELKLWKQKHESLDQSYQQLQMTKEQMENKLAMLSSEIERLKVLNKKKQDEIDQ 851

Query: 1355 ENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTH------Q 1408
            +NQ   ++ +Q + +++ +   + +              +++D + K+ E+TH      +
Sbjct: 852  QNQELIKL-DQEMNDLHNQLEDINELKTQLGSLENQLQQQIDDNQDKLNEITHLKQQVAE 910

Query: 1409 LE--LKDSEIYQKTHEYTITLTQRNDEF-ENVRQQLVEYEKRI---EDLTYEKESELAIL 1462
            +E  L + E  Q   +   T +Q  DE  +  +Q+L + E +I   ED+ Y+ E ++A+L
Sbjct: 911  IEGLLVNQEDLQNQIKKLETESQSKDEIIDQFKQKLTQLESKIAELEDIKYKYEDKMALL 970

Query: 1463 RLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEE---EVAKT 1519
                      YE   K+ E +  +L  +++    +    +++V EL K L +   E +K 
Sbjct: 971  ----SSEVKRYEFKAKKLEDKSNELTTQVDHLTADLNEADQKVIELEKDLGQWKFEYSKL 1026

Query: 1520 NEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKH 1557
            N +Q  ++     +V    EI  L++ V   + ++  H
Sbjct: 1027 NSLQYKIDEYSFLLVVSFAEIEALRSQVTTLNEQLDGH 1064



 Score =  127 bits (306), Expect = 3e-27
 Identities = 178/876 (20%), Positives = 396/876 (45%), Gaps = 68/876 (7%)

Query: 372  RKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEK 431
            ++  + + +++K   S L++  L Q    KI  N +      + S  K+ + +   ++++
Sbjct: 236  QRERQESQNQLKKQQSDLAA-ALKQLDQWKIKYNNLDLQHQQLSSAQKESIARVETLTQE 294

Query: 432  DTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELND 491
                         +D    Q++LE  +   G   +H G   E ++ I K+      EL  
Sbjct: 295  QNKLSTQIHQL-NEDKQKLQIELEQTK---GQLKLHQGLIGE-LDRIKKLLSDKSAELQQ 349

Query: 492  EIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVS 551
             ++    KD+   L +AE  I++LN +I + +   +  + N +L+ +  +   +N  K++
Sbjct: 350  MLQQSQQKDI--DLNNAELTISELNQKIKSLS---LLQQENQRLQHEIDESHREN-EKLA 403

Query: 552  DSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESD-VYKKMIEMENLAE 610
              N ++++  ++   L Q+  +LE +   L   +         +++ + ++  +++NL E
Sbjct: 404  QENSQLLKDIDKFKLLEQEKQQLESKVSMLASEIERLKVQLKQKNEKILEQQEDLKNLQE 463

Query: 611  TRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDA 670
             +L  I  LE+Q   L++EL    +  +E+E KL +++ L+     +  K   LE ++  
Sbjct: 464  -QLGEIEQLENQNQQLLKELEQKDKIIEELEQKLQELNVLEQKLADANNKIYDLENKVAM 522

Query: 671  LSASKKELALV----IENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEK 726
            LSA  + L  +     E LK  +EQL   +  L+     + NK     Q N +  D+LEK
Sbjct: 523  LSAESQRLRYLNDQKTEQLKNAEEQL-SDLNILKEKLSQLQNKYDAQQQVNQNYQDELEK 581

Query: 727  MSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEES-I 785
            +  +           + Q + Q    I  K    +  I  ++ +LS  +    ++ ES +
Sbjct: 582  LRGQSNQANTNIAELKRQLEEQKAQDIIHKQSNSESVIAELQQQLSSLQQSYKKVSESNL 641

Query: 786  AVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIE 845
            A  ED    L+ +   L    QE Q+       +  E++N        ++ ++++LLE++
Sbjct: 642  ANEEDPTLDLQNRLTLL---KQENQRLNQTIQQKNQEVLNH----QQQNQNLQQELLELD 694

Query: 846  H---ENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRD 902
                + KEL + N +L E+ QN      +++Q             + ++ES KY     D
Sbjct: 695  SLKVQIKELHESNTVLQEQLQNEAKGRQELEQR------------IQQTESEKY-----D 737

Query: 903  LESNLKRI-TH-EHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQL 960
            L+S    + TH E     + K + ++DL+     ++E  + + + L  + E   + + +L
Sbjct: 738  LQSKCAMLSTHIEGMKYKLDKMENVDDLKKRIQ-ELEGQLAEMQALELEIESLKDRIAEL 796

Query: 961  EAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQ 1020
            E +L+ +K   E+L+ + ++L +M  E ++  +    ++      + +N+  K    + Q
Sbjct: 797  EKELKLWKQKHESLDQSYQQL-QMTKEQMENKLAMLSSEIERL--KVLNK--KKQDEIDQ 851

Query: 1021 KDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEE 1080
            +++E+I L+Q++N+   + +  +++ +++L     +L+   ++ Q    ++   KQ   E
Sbjct: 852  QNQELIKLDQEMNDLH-NQLEDINELKTQLGSLENQLQQQIDDNQDKLNEITHLKQQVAE 910

Query: 1081 LQ-ILVREQD--DQIKELKETKLTFEMNIPKTEGMI--ISSTIEPMSDDANNVDXXXXXX 1135
            ++ +LV ++D  +QIK+L+    + +  I + +  +  + S I  + D     +      
Sbjct: 911  IEGLLVNQEDLQNQIKKLETESQSKDEIIDQFKQKLTQLESKIAELEDIKYKYEDKMALL 970

Query: 1136 XXXXXXLKVQEEEEFIQERS-VLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQE 1194
                   + + ++  ++++S  L  Q   L  +L E   K+I+LE    +  G       
Sbjct: 971  SSEVKRYEFKAKK--LEDKSNELTTQVDHLTADLNEADQKVIELE----KDLGQWKFEYS 1024

Query: 1195 QINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQ 1230
            ++N L+ K+++ +       + +  LRS +++  +Q
Sbjct: 1025 KLNSLQYKIDEYSFLLVVSFAEIEALRSQVTTLNEQ 1060



 Score = 95.1 bits (226), Expect = 1e-17
 Identities = 184/889 (20%), Positives = 373/889 (41%), Gaps = 58/889 (6%)

Query: 698  DLENDKEDIMNKLQNYIQENMDLTDKLEK--MSAEKISELLAKI--NHEEQSKIQTQF-- 751
            D E D E   ++L+ + ++   L  +L K  +  E   EL ++I  + E+  K Q  F  
Sbjct: 56   DKEVD-ESARDELEQWKKKYFSLEARLAKYEIDNEIKDELQSRILGSQEDVKKFQIDFTK 114

Query: 752  ---GIDAKIQERD-LYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQ 807
                +D +  E + L IEN   +L   +  + RL++ +A  ED    L +K  +     Q
Sbjct: 115  AQADLDNQKSEMNKLIIEN--QKLLNQQVEVERLKKLVAEREDTISQLLQKCKEYQEQFQ 172

Query: 808  EKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQI 867
            E + A+ +  +Q+    N+   LM  +   +K +     + KE+ +    L E N     
Sbjct: 173  ELE-AFQQ-ALQDMHNQNQGKELMI-ETWKQKYIENDNKKQKEIDELKSKLAEFNPAEVQ 229

Query: 868  SLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIED 927
            +L D  Q      E  N+    +S+      QL   +     +  +HQ L   +K+ I  
Sbjct: 230  NLKDQFQRERQ--ESQNQLKKQQSDLAAALKQLDQWKIKYNNLDLQHQQLSSAQKESIAR 287

Query: 928  LEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLE 987
            +E     Q + + +  ++  +K +  IE + Q + QL+ ++  I  L+   + L+  + E
Sbjct: 288  VETLTQEQNKLSTQIHQLNEDKQKLQIE-LEQTKGQLKLHQGLIGELDRIKKLLSDKSAE 346

Query: 988  LIDKHVQKQQTQSP-DYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDY 1046
            L     Q QQ     +  E  I+E+N+    L    +E   L  +I+ +      +  + 
Sbjct: 347  LQQMLQQSQQKDIDLNNAELTISELNQKIKSLSLLQQENQRLQHEIDESHRENEKLAQE- 405

Query: 1047 ESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNI 1106
             S+L +   K + +E+E Q++  ++       E L++ +++++++I E +E     +  +
Sbjct: 406  NSQLLKDIDKFKLLEQEKQQLESKVSMLASEIERLKVQLKQKNEKILEQQEDLKNLQEQL 465

Query: 1107 PKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNT 1166
             + E +   +  + +  +    D              ++E E+ +QE +VL+++ A  N 
Sbjct: 466  GEIEQL--ENQNQQLLKELEQKDKI------------IEELEQKLQELNVLEQKLADANN 511

Query: 1167 ELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISS 1226
            ++ +   K+  L   +  L     +N ++  QLK+  EQL+  N  L   +++L++   +
Sbjct: 512  KIYDLENKVAMLSAESQRLR---YLNDQKTEQLKNAEEQLSDLNI-LKEKLSQLQNKYDA 567

Query: 1227 AVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKI 1286
                      EL K      +A+    E  L+ QL   E K + ++   QS+++    ++
Sbjct: 568  QQQVNQNYQDELEKLRGQSNQANTNIAE--LKRQLE--EQKAQDIIHK-QSNSESVIAEL 622

Query: 1287 VTMEQVTSLQNKLQD-KEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXX 1345
               +Q++SLQ   +   E +L N ++   D+ N++ +L+ E +                 
Sbjct: 623  --QQQLSSLQQSYKKVSESNLANEEDPTLDLQNRLTLLKQENQRLNQTIQQKNQEVLNHQ 680

Query: 1346 XXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLEL 1405
                 +L+ E      ++ Q I  ++E N  L++              R+   E++  +L
Sbjct: 681  QQNQ-NLQQELLELDSLKVQ-IKELHESNTVLQEQLQNEAKGRQELEQRIQQTESEKYDL 738

Query: 1406 THQLELKDSEIYQKTH-----EYTITLTQRNDEFEN--VRQQLVEYE-KRIEDLTYEKES 1457
              +  +  + I    +     E    L +R  E E      Q +E E + ++D   E E 
Sbjct: 739  QSKCAMLSTHIEGMKYKLDKMENVDDLKKRIQELEGQLAEMQALELEIESLKDRIAELEK 798

Query: 1458 ELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVA 1517
            EL + + K       Y+ +Q   E    KL   L+ +I     LNK+  +      +E+ 
Sbjct: 799  ELKLWKQKHESLDQSYQQLQMTKEQMENKLAM-LSSEIERLKVLNKKKQDEIDQQNQELI 857

Query: 1518 KTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQ 1566
            K ++    L NQ  +I  L  ++ +L+N ++      Q  ++  +  KQ
Sbjct: 858  KLDQEMNDLHNQLEDINELKTQLGSLENQLQQQIDDNQDKLNEITHLKQ 906



 Score = 95.1 bits (226), Expect = 1e-17
 Identities = 164/791 (20%), Positives = 335/791 (42%), Gaps = 72/791 (9%)

Query: 843  EIEHENK-ELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLR 901
            EI++E K ELQ +     E+ +  QI  +  Q   +    + N+  +   E+ K   Q  
Sbjct: 85   EIDNEIKDELQSRILGSQEDVKKFQIDFTKAQADLDNQKSEMNKLII---ENQKLLNQQV 141

Query: 902  DLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLE 961
            ++E  LK++  E +  I Q  ++ ++ + +F  ++E+    ++ L + + +N      +E
Sbjct: 142  EVE-RLKKLVAEREDTISQLLQKCKEYQEQFQ-ELEAF---QQALQDMHNQNQGKELMIE 196

Query: 962  AQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINK----LNAL 1017
               Q+Y  N       ++EL     E     VQ  + Q     ++  N++ K    L A 
Sbjct: 197  TWKQKYIENDNKKQKEIDELKSKLAEFNPAEVQNLKDQFQRERQESQNQLKKQQSDLAAA 256

Query: 1018 LKQKDEEIIALN------QKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQL 1071
            LKQ D+  I  N      Q++++AQ   ++ V     +  + +T++  + E+ Q++  +L
Sbjct: 257  LKQLDQWKIKYNNLDLQHQQLSSAQKESIARVETLTQEQNKLSTQIHQLNEDKQKLQIEL 316

Query: 1072 LDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMII-----SSTIEPMSDDAN 1126
              +K   +  Q L+ E D   K L +     +  + +++   I       TI  ++    
Sbjct: 317  EQTKGQLKLHQGLIGELDRIKKLLSDKSAELQQMLQQSQQKDIDLNNAELTISELNQKIK 376

Query: 1127 NVDXXXXXXXXXXXXL--KVQEEEEFIQERSVLQEQSAK---LNTELQECYTKI----IQ 1177
            ++             +    +E E+  QE S L +   K   L  E Q+  +K+     +
Sbjct: 377  SLSLLQQENQRLQHEIDESHRENEKLAQENSQLLKDIDKFKLLEQEKQQLESKVSMLASE 436

Query: 1178 LETLNTELTGHD---VVNQEQINQLKSKL---EQLNTENDNLLSTVAELRSSISSAVDQR 1231
            +E L  +L   +   +  QE +  L+ +L   EQL  +N  LL  + E +  I   ++Q+
Sbjct: 437  IERLKVQLKQKNEKILEQQEDLKNLQEQLGEIEQLENQNQQLLKEL-EQKDKIIEELEQK 495

Query: 1232 GFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKY----EQLLDSVQSSTQEETNKIV 1287
              E+  L +Q LA         E+++   LSA   +     +Q  + ++++ ++ ++  +
Sbjct: 496  LQELNVL-EQKLADANNKIYDLENKV-AMLSAESQRLRYLNDQKTEQLKNAEEQLSDLNI 553

Query: 1288 TMEQVTSLQNKLQDKEEHLRNLQ---EKYADVINQ----IEILRSEIEDEKVA-FXXXXX 1339
              E+++ LQNK   +++  +N Q   EK     NQ    I  L+ ++E++K         
Sbjct: 554  LKEKLSQLQNKYDAQQQVNQNYQDELEKLRGQSNQANTNIAELKRQLEEQKAQDIIHKQS 613

Query: 1340 XXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAE 1399
                        L +  QSYK++ E ++ N  +    L+                +    
Sbjct: 614  NSESVIAELQQQLSSLQQSYKKVSESNLANEEDPTLDLQNRLTLLKQENQRLNQTIQQKN 673

Query: 1400 AKVLELTHQ--------LELKDSEI-YQKTHEYTITLTQRNDEFENVRQQLVEYEKRIED 1450
             +VL    Q        LEL   ++  ++ HE    L ++       RQ+L +  ++ E 
Sbjct: 674  QEVLNHQQQNQNLQQELLELDSLKVQIKELHESNTVLQEQLQNEAKGRQELEQRIQQTES 733

Query: 1451 LTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELN- 1509
              Y+ +S+ A+  L  H     Y+  + E+  +  K I+EL  ++ E  +L  ++  L  
Sbjct: 734  EKYDLQSKCAM--LSTHIEGMKYKLDKMENVDDLKKRIQELEGQLAEMQALELEIESLKD 791

Query: 1510 --KALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQG 1567
                LE+E+    +   +L+ Q  + + +  E   ++N +   SS+I++ +   +  KQ 
Sbjct: 792  RIAELEKELKLWKQKHESLD-QSYQQLQMTKE--QMENKLAMLSSEIER-LKVLNKKKQD 847

Query: 1568 RDEQLDNTMNK 1578
              +Q +  + K
Sbjct: 848  EIDQQNQELIK 858



 Score = 92.7 bits (220), Expect = 8e-17
 Identities = 130/644 (20%), Positives = 292/644 (45%), Gaps = 51/644 (7%)

Query: 234  DEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXX 293
            DE  R  + +  ++ ++    +  KLLE  + ++  + S LA E+E+             
Sbjct: 393  DESHRENEKLAQENSQLLKDIDKFKLLEQEKQQLESKVSMLASEIERLKVQLKQKNEKIL 452

Query: 294  XLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTN----------- 342
               ++ ++   E+  EIE+  +     + EL +K +++E L  ++++ N           
Sbjct: 453  E-QQEDLKNLQEQLGEIEQLENQNQQLLKELEQKDKIIEELEQKLQELNVLEQKLADANN 511

Query: 343  --KELENKLATMGTESKAVS-SPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTD 399
               +LENK+A +  ES+ +     +K   L + +   +  + +K   SQL ++    D  
Sbjct: 512  KIYDLENKVAMLSAESQRLRYLNDQKTEQLKNAEEQLSDLNILKEKLSQLQNK---YDAQ 568

Query: 400  KKINKN---EIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLE- 455
            +++N+N   E+ KL       N ++ + +  + E+              +++IA+LQ + 
Sbjct: 569  QQVNQNYQDELEKLRGQSNQANTNIAELKRQLEEQ--KAQDIIHKQSNSESVIAELQQQL 626

Query: 456  --HQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQIT 513
               QQ  +  S  ++    +   ++      LKQE N  +    ++   +++ + ++Q  
Sbjct: 627  SSLQQSYKKVSESNLANEEDPTLDLQNRLTLLKQE-NQRLNQ-TIQQKNQEVLNHQQQNQ 684

Query: 514  QLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTE-ELHHLSQKVA 572
             L  E+   +   +++K  H+     +Q+ + N +K     ++ ++ TE E + L  K A
Sbjct: 685  NLQQELLELDSLKVQIKELHESN-TVLQEQLQNEAKGRQELEQRIQQTESEKYDLQSKCA 743

Query: 573  ELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEME-NLAETRLKAISL--LESQKFDLVQE 629
             L      ++  L   D    ++ D+ K++ E+E  LAE +   + +  L+ +  +L +E
Sbjct: 744  MLSTHIEGMKYKL---DKMENVD-DLKKRIQELEGQLAEMQALELEIESLKDRIAELEKE 799

Query: 630  LHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDK 689
            L + +QK++ ++       QLQ  +   E K   L  +I+ L    K+    I+    + 
Sbjct: 800  LKLWKQKHESLDQ---SYQQLQMTKEQMENKLAMLSSEIERLKVLNKKKQDEIDQQNQEL 856

Query: 690  EQLYGTIKDLENDKEDI------MNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEE 743
             +L   + DL N  EDI      +  L+N +Q+ +D  D  +K++  +I+ L  ++  E 
Sbjct: 857  IKLDQEMNDLHNQLEDINELKTQLGSLENQLQQQID--DNQDKLN--EITHLKQQV-AEI 911

Query: 744  QSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLG 803
            +  +  Q  +  +I++ +   ++ +  + ++K ++ +LE  IA +ED +Y  E K   L 
Sbjct: 912  EGLLVNQEDLQNQIKKLETESQSKDEIIDQFKQKLTQLESKIAELEDIKYKYEDKMALLS 971

Query: 804  SYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHE 847
            S ++  +    +   + +EL  ++  L       +++++E+E +
Sbjct: 972  SEVKRYEFKAKKLEDKSNELTTQVDHLTADLNEADQKVIELEKD 1015



 Score = 82.2 bits (194), Expect = 1e-13
 Identities = 125/596 (20%), Positives = 270/596 (45%), Gaps = 49/596 (8%)

Query: 213  DTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHS 272
            + ++ +  +QE    +E + +++ Q+LLK++E KD  I  LE+  + L     +++  ++
Sbjct: 453  EQQEDLKNLQEQLGEIE-QLENQNQQLLKELEQKDKIIEELEQKLQELNVLEQKLADANN 511

Query: 273  KLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLE 332
            K+  +LE               L  Q  E     + ++ +   L+   +++L  K +  +
Sbjct: 512  KI-YDLENKVAMLSAESQRLRYLNDQKTEQLKNAEEQLSDLNILK-EKLSQLQNKYDAQQ 569

Query: 333  HLNCQIRQTNKELENKLATMGTESKAVSS--PSKKGSPLISRKSGRNTASKMKSPWSQLS 390
             +N   +   ++L  +     T    +      +K   +I ++S  N+ S +     QLS
Sbjct: 570  QVNQNYQDELEKLRGQSNQANTNIAELKRQLEEQKAQDIIHKQS--NSESVIAELQQQLS 627

Query: 391  SETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIA 450
            S    Q + KK++++ +A  E     L   L      + +++            ++ L  
Sbjct: 628  S---LQQSYKKVSESNLANEEDPTLDLQNRL-----TLLKQENQRLNQTIQQKNQEVLNH 679

Query: 451  QLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEE 510
            Q Q ++ Q      L+ + +    + E+ +    L+++L +E K    ++L ++++  E 
Sbjct: 680  QQQNQNLQQ----ELLELDSLKVQIKELHESNTVLQEQLQNEAK--GRQELEQRIQQTES 733

Query: 511  QITQLNDEIDAANKNMIKVKSNHKL-KLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQ 569
            +   L  +    + ++  +K  +KL K++ +        ++     E+  L  E+  L  
Sbjct: 734  EKYDLQSKCAMLSTHIEGMK--YKLDKMENVDDLKKRIQELEGQLAEMQALELEIESLKD 791

Query: 570  KVAELEEE-KGNLQLH-LVD--YDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFD 625
            ++AELE+E K   Q H  +D  Y   +M +  +  K+  + +  E RLK ++  +  + D
Sbjct: 792  RIAELEKELKLWKQKHESLDQSYQQLQMTKEQMENKLAMLSSEIE-RLKVLNKKKQDEID 850

Query: 626  LV-QELHILQQKYDEVEDKLADISQLQSDQVCSEIK-SVHLEEQIDALS--ASKKELALV 681
               QEL  L Q+ +++ ++L DI++L++     E +    +++  D L+     K+    
Sbjct: 851  QQNQELIKLDQEMNDLHNQLEDINELKTQLGSLENQLQQQIDDNQDKLNEITHLKQQVAE 910

Query: 682  IENLKLDKEQLYGTIKDLEND---KEDI-------MNKLQNYIQENMDL----TDKLEKM 727
            IE L +++E L   IK LE +   K++I       + +L++ I E  D+     DK+  +
Sbjct: 911  IEGLLVNQEDLQNQIKKLETESQSKDEIIDQFKQKLTQLESKIAELEDIKYKYEDKMALL 970

Query: 728  SAE-KISELLAKINHEEQSKIQTQFG-IDAKIQERDLYIENIESELSKYKSRICRL 781
            S+E K  E  AK   ++ +++ TQ   + A + E D  +  +E +L ++K    +L
Sbjct: 971  SSEVKRYEFKAKKLEDKSNELTTQVDHLTADLNEADQKVIELEKDLGQWKFEYSKL 1026



 Score = 41.1 bits (92), Expect = 0.25
 Identities = 88/465 (18%), Positives = 191/465 (41%), Gaps = 43/465 (9%)

Query: 155  DNALSVLQVKMKIMETTILDLQEK--INEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXE 212
            ++ ++ LQ ++  ++ +   + E    NE+D  ++ +N+ T                  E
Sbjct: 616  ESVIAELQQQLSSLQQSYKKVSESNLANEEDPTLDLQNRLTLLKQENQRLNQTIQQKNQE 675

Query: 213  --DTKQQMTKMQENFIAMEA------EWKDEKQRLLKDIESKDVRISSLEEANKLLEAAR 264
              + +QQ   +Q+  + +++      E  +    L + ++++      LE+  +  E+ +
Sbjct: 676  VLNHQQQNQNLQQELLELDSLKVQIKELHESNTVLQEQLQNEAKGRQELEQRIQQTESEK 735

Query: 265  FEISLEHSKLAQELEQXXXXXXXXXXXXXXLAK-QSIEPSCEEKTEIE-EKGSLEIANMT 322
            +++  + + L+  +E                 + Q +E    E   +E E  SL+   + 
Sbjct: 736  YDLQSKCAMLSTHIEGMKYKLDKMENVDDLKKRIQELEGQLAEMQALELEIESLK-DRIA 794

Query: 323  ELTKKIEL-------LEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSG 375
            EL K+++L       L+    Q++ T +++ENKLA + +E + +   +KK    I +++ 
Sbjct: 795  ELEKELKLWKQKHESLDQSYQQLQMTKEQMENKLAMLSSEIERLKVLNKKKQDEIDQQN- 853

Query: 376  RNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXX 435
                 K+    + L     NQ  D    K ++  LE  +Q    D  DK   I+      
Sbjct: 854  -QELIKLDQEMNDLH----NQLEDINELKTQLGSLENQLQQQIDDNQDKLNEITHLKQQV 908

Query: 436  XXXXXXXXGKDTL---IAQLQLEHQQHME-----GPSLIHVGTNTEDVNEIAKVQEQLKQ 487
                     ++ L   I +L+ E Q   E        L  + +   ++ +I    E    
Sbjct: 909  AEIEGLLVNQEDLQNQIKKLETESQSKDEIIDQFKQKLTQLESKIAELEDIKYKYEDKMA 968

Query: 488  ELNDEIK--DVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSN------HKLKLKQ 539
             L+ E+K  +   K L +K      Q+  L  +++ A++ +I+++ +         KL  
Sbjct: 969  LLSSEVKRYEFKAKKLEDKSNELTTQVDHLTADLNEADQKVIELEKDLGQWKFEYSKLNS 1028

Query: 540  MQKTIDNFS-KVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQL 583
            +Q  ID +S  +  S  EI  L  ++  L++++   ++ K  L L
Sbjct: 1029 LQYKIDEYSFLLVVSFAEIEALRSQVTTLNEQLDGHQKTKVALAL 1073


>UniRef50_A0DI28 Cluster: Chromosome undetermined scaffold_51, whole
            genome shotgun sequence; n=1; Paramecium tetraurelia|Rep:
            Chromosome undetermined scaffold_51, whole genome shotgun
            sequence - Paramecium tetraurelia
          Length = 1335

 Score =  136 bits (330), Expect = 4e-30
 Identities = 184/919 (20%), Positives = 441/919 (47%), Gaps = 79/919 (8%)

Query: 454  LEHQQHMEGPSLIHVGTNTEDVN----EIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAE 509
            + +   + G  +I +     D+N    E A+  + L Q+LN +I++  ++  IE LK   
Sbjct: 64   INNSDDVSGAKIIQLEVEIHDLNQQLQESAQKIKALTQQLNAKIEENEME--IEILKDDH 121

Query: 510  EQ-ITQLNDEIDAANKNMIKVKSNHK-LKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHL 567
            ++ ++    +I+A  K + +++   K  + KQ Q+     ++++D  + + ++    + +
Sbjct: 122  QKSLSDQQIQIEALQKTINELQQLQKNTETKQSQEIAP--TQLNDQEELLQKIQNLTNQI 179

Query: 568  SQKVAELE-EEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAE--TRLKAISLL---ES 621
             Q   +LE ++K   QL L +   G M E    +   E +NL E   +L+ + L    E+
Sbjct: 180  EQYAKQLEIKDKQIEQLQLNEGKQGSMEEVGK-RSQEEDQNLEEKIAQLEEVLLQYQEEN 238

Query: 622  QKFDLVQEL-----HILQQKYDEVEDKLADISQLQSD-QVCSEIKSVHLE--EQIDALSA 673
             +F   +E        L+Q+ + +E ++ +I Q + D  V  +++ + LE  E ++  ++
Sbjct: 239  SQFAAKEEASQKEKQQLKQQLESLEKQIKEIQQQEQDASVAQQLEDLKLEYEELVEEYTS 298

Query: 674  SKKELALV-IENLKL-DKEQLYGTIKD-LENDKEDIMNKLQNY---IQENMDLTDKLEKM 727
            + ++L    +E  +L DK Q Y ++K+ L++        LQ++   ++EN +L   + K 
Sbjct: 299  TNEKLQQSELECQQLTDKCQEYLSVKEQLQDQITQFETTLQHHNEVLEENNELKQLMNKA 358

Query: 728  SAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAV 787
            S E+I+ L +  N+E Q+ +  Q   + +  +  L+I   E +   Y++   +  + +  
Sbjct: 359  S-EQINNLQS--NNEYQT-LYLQLRDEYEEFKEQLHITIKEKDQQLYQA--AQFCQELEA 412

Query: 788  MEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVE---KQLLEI 844
             +++ + LE     L + LQ + +   +Y  + +EL N+L  L + ++ V    ++L ++
Sbjct: 413  FKEQAHMLEENNTLLSNQLQTQLENNEKYQQRIEELENQLNTLQNQNQDVNDLMQKLDQL 472

Query: 845  EHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLE 904
            + +N+ L+ +N    E  +N +I +  ++Q      +K ++     SE+T    +L++  
Sbjct: 473  KQDNENLKTQNYEYDEMIKNYEIQMDALKQIECDSPKKISKLQQENSETTAEYIKLKE-- 530

Query: 905  SNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQL 964
             N +R  H    L+ Q++  +++  +E  + +++ I   +    K +  I+Y  +L++  
Sbjct: 531  -NTQREIH----LLKQERTNLQNEIVEIKSLLDTYINSGETFESKTQYIIDYWNKLQSIQ 585

Query: 965  QEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQK--- 1021
             E  N +E   + ++ELN+ N+      +Q  Q  S D+  Q +N+  ++N+  K +   
Sbjct: 586  DEQNNLVEKFQLEIQELNE-NI----GQIQSLQNLSTDH--QQLNQELQINSSEKNELAA 638

Query: 1022 DEEI-IALNQKINNAQVS----YMSMVSDYESKLAQFTTKLENM------EEEMQRVSKQ 1070
            DE + ++L + + N + +    +  +    +++  + +T+ E++      ++++Q+  +Q
Sbjct: 639  DENLNLSLEKLVTNEETNQNNFHFEVKKVQQTEYVEISTQTEDVIEQNQQQDQVQQQEQQ 698

Query: 1071 LLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDX 1130
                +Q  ++ Q   ++Q  Q ++ ++ +  +E  + +T+ +I S+   P + D    D 
Sbjct: 699  QEQQQQQQQQQQQQQQQQQQQQQQQQQEQKQYESQLIQTDDVIFSA---PQNSDKETNDQ 755

Query: 1131 XXXXXXXXXXXLKV--QEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGH 1188
                        ++  Q  E+   E++ ++  S +LN E     + I +L   N +L G 
Sbjct: 756  LCQTDEQKEDLQEIQGQNSEQQNNEQNGIELNSQQLNGEQDHDQSIITKLMQPNEDLDGQ 815

Query: 1189 DVVNQE--QINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQR 1246
                Q+  Q +QLK K+E ++    +L   V  L+   +  ++++  +I +       Q 
Sbjct: 816  GSQFQDLNQTDQLKKKVEDMDNLRKSLEKEVYNLKDK-NKKLEEK-LQIIQKPGTPRKQS 873

Query: 1247 EADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTME--QVTSLQNKLQDKEE 1304
            +A  ++ + +    +   + + ++L + +QS    + N+ +  +  ++  LQ++++  +E
Sbjct: 874  DAKEERKKQQDNELIQRLQKQIKELQEEIQSFNVHQLNEQIEQQSNEIEQLQSEIEQYKE 933

Query: 1305 HLRNLQEKYADVINQIEIL 1323
             L   +++     NQ++ +
Sbjct: 934  QLIKQKQQTIKFKNQLDTI 952



 Score =  107 bits (256), Expect = 3e-21
 Identities = 193/971 (19%), Positives = 409/971 (42%), Gaps = 86/971 (8%)

Query: 650  LQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNK 709
            LQ  ++  EI  +   EQ+  L    KE    I+  KLD       IK+L+   ++ + K
Sbjct: 3    LQVQKLQQEITDLKEYEQM--LEDQIKEHEETIDKQKLDLNTKETEIKNLKKQLQEAIKK 60

Query: 710  LQNYIQENMDLTD-KLEKMSAEKISELLAKINHEEQS-KIQTQFGIDAKIQERDLYIENI 767
              + I  + D++  K+ ++  E I +L  ++    Q  K  TQ  ++AKI+E ++ IE +
Sbjct: 61   A-DVINNSDDVSGAKIIQLEVE-IHDLNQQLQESAQKIKALTQ-QLNAKIEENEMEIEIL 117

Query: 768  ESE----LSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDEL 823
            + +    LS  + +I  L+++I  ++  + + E K  Q  +  Q   +      IQ   L
Sbjct: 118  KDDHQKSLSDQQIQIEALQKTINELQQLQKNTETKQSQEIAPTQLNDQEELLQKIQN--L 175

Query: 824  VNRLAVLMDHDRVVEKQLLEIE-HENKE--LQKKNQILLEENQNLQISLSDMQ----QHY 876
             N++        + +KQ+ +++ +E K+  +++  +   EE+QNL+  ++ ++    Q+ 
Sbjct: 176  TNQIEQYAKQLEIKDKQIEQLQLNEGKQGSMEEVGKRSQEEDQNLEEKIAQLEEVLLQYQ 235

Query: 877  NALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQI 936
                + A + + ++ E  + + QL  LE  +K I  + Q   V +  ++EDL++E+    
Sbjct: 236  EENSQFAAKEEASQKEKQQLKQQLESLEKQIKEIQQQEQDASVAQ--QLEDLKLEY---- 289

Query: 937  ESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQ 996
            E  + +    NEK +++     QL  + QEY        ++V+E      +L D+  Q +
Sbjct: 290  EELVEEYTSTNEKLQQSELECQQLTDKCQEY--------LSVKE------QLQDQITQFE 335

Query: 997  QTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTK 1056
             T    +  + + E N+L  L+ +  E+I  L Q  N  Q  Y+ +  +YE    Q    
Sbjct: 336  TTLQ--HHNEVLEENNELKQLMNKASEQINNL-QSNNEYQTLYLQLRDEYEEFKEQLHIT 392

Query: 1057 LENMEEEMQRVSKQLLDSKQHNEELQILVREQ---DDQIKELKETKLTFEMNIPKTEGMI 1113
            ++  ++++ + ++   + +   E+  +L        +Q++   E    ++  I + E  +
Sbjct: 393  IKEKDQQLYQAAQFCQELEAFKEQAHMLEENNTLLSNQLQTQLENNEKYQQRIEELENQL 452

Query: 1114 ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQ--EEEEFIQERSVLQEQSAKLNTELQEC 1171
              +T++  + D N++             LK Q  E +E I+   +  +   ++  +  + 
Sbjct: 453  --NTLQNQNQDVNDLMQKLDQLKQDNENLKTQNYEYDEMIKNYEIQMDALKQIECDSPK- 509

Query: 1172 YTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQR 1231
              KI +L+  N+E T   +  +E   +   ++  L  E  NL + + E++S + + ++  
Sbjct: 510  --KISKLQQENSETTAEYIKLKENTQR---EIHLLKQERTNLQNEIVEIKSLLDTYINSG 564

Query: 1232 GFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQ 1291
              E  E   Q++       Q  + E    +  F+ + ++L +++    Q   N     +Q
Sbjct: 565  --ETFESKTQYIIDYWNKLQSIQDEQNNLVEKFQLEIQELNENI-GQIQSLQNLSTDHQQ 621

Query: 1292 VTS-LQNKLQDKEEHL--RNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXX 1348
            +   LQ    +K E     NL      ++   E  ++    E                  
Sbjct: 622  LNQELQINSSEKNELAADENLNLSLEKLVTNEETNQNNFHFE---VKKVQQTEYVEISTQ 678

Query: 1349 XXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQ 1408
              D+  +NQ   Q+Q+Q      +E  Q ++              +    E K  E    
Sbjct: 679  TEDVIEQNQQQDQVQQQEQ---QQEQQQQQQQQQQQQQQQQQQQQQQQQQEQKQYE---- 731

Query: 1409 LELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHE 1468
                 S++ Q T +   +  Q +D+  N   QL + +++ EDL  E + + +  +    +
Sbjct: 732  -----SQLIQ-TDDVIFSAPQNSDKETN--DQLCQTDEQKEDLQ-EIQGQNSEQQ-NNEQ 781

Query: 1469 NANHYETMQKESEIERVKLIEELNVKITESVS-LNKQVAELNKALEEEVAKTNEMQTALE 1527
            N     + Q   E +  + I    ++  E +     Q  +LN+  ++   K  +M    +
Sbjct: 782  NGIELNSQQLNGEQDHDQSIITKLMQPNEDLDGQGSQFQDLNQT-DQLKKKVEDMDNLRK 840

Query: 1528 NQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRA 1587
            + E E+  L D+   L+  ++             SD K+ R +Q DN + + L   +   
Sbjct: 841  SLEKEVYNLKDKNKKLEEKLQIIQKPGTPRKQ--SDAKEERKKQQDNELIQRLQKQIKEL 898

Query: 1588 ELDLAMYMLHQ 1598
            + ++  + +HQ
Sbjct: 899  QEEIQSFNVHQ 909



 Score =  100 bits (240), Expect = 3e-19
 Identities = 214/1059 (20%), Positives = 447/1059 (42%), Gaps = 88/1059 (8%)

Query: 498  VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSN--- 554
            + DL E  +  E+QI +  + ID    ++   ++  K   KQ+Q+ I     +++S+   
Sbjct: 12   ITDLKEYEQMLEDQIKEHEETIDKQKLDLNTKETEIKNLKKQLQEAIKKADVINNSDDVS 71

Query: 555  -KEIVRLTEELHHLSQKVAELEEE-KGNLQLHLVDYDSGRM----IESDVYKKMIEMENL 608
              +I++L  E+H L+Q++ E  ++ K   Q      +   M    ++ D  K + + +  
Sbjct: 72   GAKIIQLEVEIHDLNQQLQESAQKIKALTQQLNAKIEENEMEIEILKDDHQKSLSDQQIQ 131

Query: 609  AETRLKAISLLE--SQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHL-E 665
             E   K I+ L+   +  +  Q   I   + ++ E+ L  I  L ++Q+    K + + +
Sbjct: 132  IEALQKTINELQQLQKNTETKQSQEIAPTQLNDQEELLQKIQNL-TNQIEQYAKQLEIKD 190

Query: 666  EQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLE 725
            +QI+ L  ++ +   + E  K  +E+     ++LE     +   L  Y +EN     K E
Sbjct: 191  KQIEQLQLNEGKQGSMEEVGKRSQEE----DQNLEEKIAQLEEVLLQYQEENSQFAAKEE 246

Query: 726  KMSAEKISELLAKINH-EEQSKIQTQFGIDAKI--QERDLYIENIESELSKYKSRICRLE 782
                EK  +L  ++   E+Q K   Q   DA +  Q  DL +E  E  + +Y S   +L+
Sbjct: 247  ASQKEK-QQLKQQLESLEKQIKEIQQQEQDASVAQQLEDLKLE-YEELVEEYTSTNEKLQ 304

Query: 783  ESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLL 842
            +S           ++  D+   YL  K++   + T  E  L +   VL +++ +  KQL+
Sbjct: 305  QS-------ELECQQLTDKCQEYLSVKEQLQDQITQFETTLQHHNEVLEENNEL--KQLM 355

Query: 843  EIEHEN-KELQKKNQILLEENQNLQISLSD-----MQQHYNALVEKANRTDLAE---SES 893
                E    LQ  N     E Q L + L D      +Q +  + EK  +   A     E 
Sbjct: 356  NKASEQINNLQSNN-----EYQTLYLQLRDEYEEFKEQLHITIKEKDQQLYQAAQFCQEL 410

Query: 894  TKYQTQLRDLESNLKRITHEHQTLIVQKKK---EIEDLEIEFNTQIESAIRDKKVLNEKY 950
              ++ Q   LE N   ++++ QT +   +K    IE+LE + NT +++  +D   L +K 
Sbjct: 411  EAFKEQAHMLEENNTLLSNQLQTQLENNEKYQQRIEELENQLNT-LQNQNQDVNDLMQKL 469

Query: 951  EKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINE 1010
            ++  +    L+ Q  EY   I+N  + ++ L ++  +   K + K Q ++ + T +YI  
Sbjct: 470  DQLKQDNENLKTQNYEYDEMIKNYEIQMDALKQIECD-SPKKISKLQQENSETTAEYIK- 527

Query: 1011 INKLNALLKQKDEEIIALNQKINNAQ---VSYMSMVSDYESKLAQFTTKLENMEEEMQRV 1067
                  L +    EI  L Q+  N Q   V   S++  Y +    F +K + + +   ++
Sbjct: 528  ------LKENTQREIHLLKQERTNLQNEIVEIKSLLDTYINSGETFESKTQYIIDYWNKL 581

Query: 1068 SKQLLDSKQHN--EELQILVREQDDQIKELKETK-LTFEMNIPKTEGMIISSTIEPMSDD 1124
              Q +  +Q+N  E+ Q+ ++E ++ I +++  + L+ +      E  I SS    ++ D
Sbjct: 582  --QSIQDEQNNLVEKFQLEIQELNENIGQIQSLQNLSTDHQQLNQELQINSSEKNELAAD 639

Query: 1125 AN-NVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNT-ELQECYTKIIQLETLN 1182
             N N+                  E + +Q+   ++  +   +  E  +   ++ Q E   
Sbjct: 640  ENLNLSLEKLVTNEETNQNNFHFEVKKVQQTEYVEISTQTEDVIEQNQQQDQVQQQEQQQ 699

Query: 1183 TELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQH 1242
             +        Q+Q  Q + + +Q   E     S + +    I SA      E  +   Q 
Sbjct: 700  EQQQQQQQQQQQQQQQQQQQQQQQQQEQKQYESQLIQTDDVIFSAPQNSDKETNDQLCQT 759

Query: 1243 LAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDK 1302
              Q+E D Q+ + +   Q +  ++  E  L+S Q + +++ ++        S+  KL   
Sbjct: 760  DEQKE-DLQEIQGQNSEQQNNEQNGIE--LNSQQLNGEQDHDQ--------SIITKLMQP 808

Query: 1303 EEHLRNLQEKYADVINQIEILRSEIED-EKVAFXXXXXXXXXXXXXXXXDLRTE-NQSYK 1360
             E L     ++ D +NQ + L+ ++ED + +                  + + +  Q   
Sbjct: 809  NEDLDGQGSQFQD-LNQTDQLKKKVEDMDNLRKSLEKEVYNLKDKNKKLEEKLQIIQKPG 867

Query: 1361 QMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKT 1420
              ++QS  +  EE  + + +             +       V +L  Q+E + +EI Q  
Sbjct: 868  TPRKQS--DAKEERKKQQDNELIQRLQKQIKELQEEIQSFNVHQLNEQIEQQSNEIEQLQ 925

Query: 1421 HEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKES 1480
             E    + Q  ++    +QQ ++++ +++ +       L +L+ +  +  +  + +Q+E 
Sbjct: 926  SE----IEQYKEQLIKQKQQTIKFKNQLDTIYNLGPQALTMLQSEPKKEFSSTQLIQQEK 981

Query: 1481 -EIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAK 1518
             +I     I+       + + LN++  +L ++++ ++ K
Sbjct: 982  YQISSFLYIKSQKSYQCQFIELNRKQIKLFQSIKGKIEK 1020



 Score = 91.9 bits (218), Expect = 1e-16
 Identities = 145/724 (20%), Positives = 305/724 (42%), Gaps = 57/724 (7%)

Query: 887  DLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNT---QIESAIRDK 943
            DL   +  +  T L++ E  L+    EH+  I ++K ++   E E      Q++ AI+  
Sbjct: 2    DLQVQKLQQEITDLKEYEQMLEDQIKEHEETIDKQKLDLNTKETEIKNLKKQLQEAIKKA 61

Query: 944  KVLNEKYEKNIEYVTQLEA-------QLQEYKNNI----ENLNMNVEELNKMNLELIDKH 992
             V+N   + +   + QLE        QLQE    I    + LN  +EE N+M +E++   
Sbjct: 62   DVINNSDDVSGAKIIQLEVEIHDLNQQLQESAQKIKALTQQLNAKIEE-NEMEIEILKDD 120

Query: 993  VQK----QQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYES 1048
             QK    QQ Q  +  ++ INE+ +L    + K  + IA  Q   N Q   +  + +  +
Sbjct: 121  HQKSLSDQQIQI-EALQKTINELQQLQKNTETKQSQEIAPTQL--NDQEELLQKIQNLTN 177

Query: 1049 KLAQFTTKLENMEEEMQRVSKQLLDSKQHN-EELQILVREQDDQIKE----LKETKLTFE 1103
            ++ Q+  +LE  +++++++  QL + KQ + EE+    +E+D  ++E    L+E  L ++
Sbjct: 178  QIEQYAKQLEIKDKQIEQL--QLNEGKQGSMEEVGKRSQEEDQNLEEKIAQLEEVLLQYQ 235

Query: 1104 MNIPKTEGMIISSTIEP--MSDDANNVDXXXXXXXXXXXXLKV-QEEEEFIQERSVLQEQ 1160
                +      +S  E   +     +++              V Q+ E+   E   L E+
Sbjct: 236  EENSQFAAKEEASQKEKQQLKQQLESLEKQIKEIQQQEQDASVAQQLEDLKLEYEELVEE 295

Query: 1161 SAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAEL 1220
                N +LQ+   +  QL     E        Q+QI Q ++ L+  N     +L    EL
Sbjct: 296  YTSTNEKLQQSELECQQLTDKCQEYLSVKEQLQDQITQFETTLQHHN----EVLEENNEL 351

Query: 1221 RSSISSAVDQ-RGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSST 1279
            +  ++ A +Q    +    ++    Q   ++++ + +L + +   + +  Q     Q   
Sbjct: 352  KQLMNKASEQINNLQSNNEYQTLYLQLRDEYEEFKEQLHITIKEKDQQLYQAAQFCQELE 411

Query: 1280 QEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXX 1339
              +    +  E  T L N+LQ + E+    Q++  ++ NQ+  L+++ +D          
Sbjct: 412  AFKEQAHMLEENNTLLSNQLQTQLENNEKYQQRIEELENQLNTLQNQNQD-----VNDLM 466

Query: 1340 XXXXXXXXXXXDLRTENQSYKQMQEQSILNINE----ENAQLKKSSXXXXXXXXXXXXRV 1395
                       +L+T+N  Y +M +   + ++     E    KK S             +
Sbjct: 467  QKLDQLKQDNENLKTQNYEYDEMIKNYEIQMDALKQIECDSPKKISKLQQENSETTAEYI 526

Query: 1396 NDAEAKVLELTHQLELKDSEIYQKTHEYTI---TLTQRNDEFENVRQQLVEYEKRIEDLT 1452
               E    E+ H L+ + + +  +  E      T     + FE+  Q +++Y  +++ + 
Sbjct: 527  KLKENTQREI-HLLKQERTNLQNEIVEIKSLLDTYINSGETFESKTQYIIDYWNKLQSIQ 585

Query: 1453 YEKESELAILRL---KMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELN 1509
             E+ + +   +L   +++EN    +++Q  S  +  +L +EL +  +E   L      LN
Sbjct: 586  DEQNNLVEKFQLEIQELNENIGQIQSLQNLS-TDHQQLNQELQINSSEKNELAAD-ENLN 643

Query: 1510 KALEEEVA--KTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQG 1567
             +LE+ V   +TN+     E ++++     +  T  ++++  +  + Q         +Q 
Sbjct: 644  LSLEKLVTNEETNQNNFHFEVKKVQQTEYVEISTQTEDVIEQNQQQDQVQQQEQQQEQQQ 703

Query: 1568 RDEQ 1571
            + +Q
Sbjct: 704  QQQQ 707



 Score = 55.6 bits (128), Expect = 1e-05
 Identities = 135/680 (19%), Positives = 278/680 (40%), Gaps = 73/680 (10%)

Query: 220 KMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELE 279
           ++Q+     E   +   + L ++ E K +   + E+ N L   +  E    + +L  E E
Sbjct: 326 QLQDQITQFETTLQHHNEVLEENNELKQLMNKASEQINNL--QSNNEYQTLYLQLRDEYE 383

Query: 280 QXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIR 339
           +                 Q+ +  C+E    +E+  +   N T L+ +++     N + +
Sbjct: 384 EFKEQLHITIKEKDQQLYQAAQ-FCQELEAFKEQAHMLEENNTLLSNQLQTQLENNEKYQ 442

Query: 340 QTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTD 399
           Q  +ELEN+L T+  +++ V+   +K   L  ++   N              +T N + D
Sbjct: 443 QRIEELENQLNTLQNQNQDVNDLMQKLDQL--KQDNENL-------------KTQNYEYD 487

Query: 400 KKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQH 459
           + I   EI      + +L +   D    IS+               +T    ++L+    
Sbjct: 488 EMIKNYEIQ-----MDALKQIECDSPKKISKLQQE---------NSETTAEYIKLKENTQ 533

Query: 460 MEGPSLIHVGTNTEDVNEIAKVQEQLKQELND----EIKDVNVKDLIEKLKSAEEQITQL 515
            E   L    TN +  NEI +++  L   +N     E K   + D   KL+S +++   L
Sbjct: 534 REIHLLKQERTNLQ--NEIVEIKSLLDTYINSGETFESKTQYIIDYWNKLQSIQDEQNNL 591

Query: 516 ND----EIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKV 571
            +    EI   N+N+ +++S   L     Q  ++   +++ S K  +   E L+   +K+
Sbjct: 592 VEKFQLEIQELNENIGQIQSLQNLSTDHQQ--LNQELQINSSEKNELAADENLNLSLEKL 649

Query: 572 AELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELH 631
              EE   N   H   ++  ++ +++  +   + E++ E   +    ++ Q+    Q+  
Sbjct: 650 VTNEETNQN-NFH---FEVKKVQQTEYVEISTQTEDVIEQNQQQ-DQVQQQEQQQEQQQQ 704

Query: 632 ILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQI-DALSASKKELALVIENLKLDKE 690
             QQ+  + + +     Q Q +Q   E + +  ++ I  A   S KE    +      KE
Sbjct: 705 QQQQQQQQQQQQQQQQQQQQQEQKQYESQLIQTDDVIFSAPQNSDKETNDQLCQTDEQKE 764

Query: 691 QLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQ 750
            L    ++++    +  N  QN I+ N    +  +      I++L+      +    Q Q
Sbjct: 765 DL----QEIQGQNSEQQNNEQNGIELNSQQLNGEQDHDQSIITKLMQPNEDLDGQGSQFQ 820

Query: 751 F-----GIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMED----RRYS---LERK 798
                  +  K+++ D   +++E E+   K +  +LEE + +++     R+ S    ERK
Sbjct: 821 DLNQTDQLKKKVEDMDNLRKSLEKEVYNLKDKNKKLEEKLQIIQKPGTPRKQSDAKEERK 880

Query: 799 ADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKEL-QKKNQI 857
             Q    +Q  QK   E  +QE+  +    V   ++++ E+Q  EIE    E+ Q K Q+
Sbjct: 881 KQQDNELIQRLQKQIKE--LQEE--IQSFNVHQLNEQI-EQQSNEIEQLQSEIEQYKEQL 935

Query: 858 LLEENQNLQISLSDMQQHYN 877
           + ++ Q ++   + +   YN
Sbjct: 936 IKQKQQTIKFK-NQLDTIYN 954



 Score = 47.6 bits (108), Expect = 0.003
 Identities = 117/667 (17%), Positives = 275/667 (41%), Gaps = 53/667 (7%)

Query: 216  QQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLA 275
            Q   + Q  ++ +  E+++ K++L   I+ KD ++    +  + LEA +     E + + 
Sbjct: 366  QSNNEYQTLYLQLRDEYEEFKEQLHITIKEKDQQLYQAAQFCQELEAFK-----EQAHML 420

Query: 276  QELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLN 335
            +E                   +Q IE    +   ++ +      ++ +L +K++ L+  N
Sbjct: 421  EENNTLLSNQLQTQLENNEKYQQRIEELENQLNTLQNQNQ----DVNDLMQKLDQLKQDN 476

Query: 336  CQIRQTNKELENKLATMGTES---KAVSSPSKKGSPLISRKSGRNTASKMK-SPWSQLSS 391
              ++  N E +  +     +    K +   S K    + +++   TA  +K    +Q   
Sbjct: 477  ENLKTQNYEYDEMIKNYEIQMDALKQIECDSPKKISKLQQENSETTAEYIKLKENTQREI 536

Query: 392  ETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQ 451
              L Q+      +NEI +++ ++ +        E                   ++ L+ +
Sbjct: 537  HLLKQERTNL--QNEIVEIKSLLDTYINSGETFESKTQYIIDYWNKLQSIQDEQNNLVEK 594

Query: 452  LQLEHQQHMEG----PSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKS 507
             QLE Q+  E      SL ++ T+ + +N+  ++    K EL     D N+   +EKL +
Sbjct: 595  FQLEIQELNENIGQIQSLQNLSTDHQQLNQELQINSSEKNEL---AADENLNLSLEKLVT 651

Query: 508  AEE-QITQLNDEIDAANKN-MIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELH 565
             EE      + E+    +   +++ +  +  ++Q Q+      +V    ++  +  ++  
Sbjct: 652  NEETNQNNFHFEVKKVQQTEYVEISTQTEDVIEQNQQQ----DQVQQQEQQQEQQQQQQQ 707

Query: 566  HLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFD 625
               Q+  + ++++   Q     Y+S ++I++D         +  ET    +   + QK D
Sbjct: 708  QQQQQQQQQQQQQQQQQQEQKQYES-QLIQTDDVIFSAPQNSDKETN-DQLCQTDEQKED 765

Query: 626  LVQELHILQQKYDEVEDKLADIS--QLQSDQVCSE---IKSVHLEEQIDALSASKKELAL 680
            L QE+     +    E    +++  QL  +Q   +    K +   E +D   +  ++L  
Sbjct: 766  L-QEIQGQNSEQQNNEQNGIELNSQQLNGEQDHDQSIITKLMQPNEDLDGQGSQFQDLNQ 824

Query: 681  VIENLKLDKEQLYGTIKDLENDK---EDIMNKLQNYIQ---------ENMDLTDKLEKMS 728
              + LK   E +    K LE +    +D   KL+  +Q         +  D  ++ +K  
Sbjct: 825  T-DQLKKKVEDMDNLRKSLEKEVYNLKDKNKKLEEKLQIIQKPGTPRKQSDAKEERKKQQ 883

Query: 729  AEKISELLAKINHEEQSKIQT--QFGIDAKIQERDLYIENIESELSKYKSRICRLEESIA 786
              ++ + L K   E Q +IQ+     ++ +I+++   IE ++SE+ +YK ++ + ++   
Sbjct: 884  DNELIQRLQKQIKELQEEIQSFNVHQLNEQIEQQSNEIEQLQSEIEQYKEQLIKQKQQTI 943

Query: 787  VMEDRRYSLERKADQLGSYLQ-EKQKAYSE-YTIQEDELVNRLAVLMDHDRVVEKQLLEI 844
              +++  ++     Q  + LQ E +K +S    IQ+++      + +   +  + Q +E+
Sbjct: 944  KFKNQLDTIYNLGPQALTMLQSEPKKEFSSTQLIQQEKYQISSFLYIKSQKSYQCQFIEL 1003

Query: 845  EHENKEL 851
              +  +L
Sbjct: 1004 NRKQIKL 1010


>UniRef50_A0CUZ8 Cluster: Chromosome undetermined scaffold_29, whole
            genome shotgun sequence; n=1; Paramecium tetraurelia|Rep:
            Chromosome undetermined scaffold_29, whole genome shotgun
            sequence - Paramecium tetraurelia
          Length = 1389

 Score =  136 bits (330), Expect = 4e-30
 Identities = 255/1291 (19%), Positives = 564/1291 (43%), Gaps = 122/1291 (9%)

Query: 317  EIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGR 376
            E+  +  L  K + ++  +   +Q N++   K+  +  + + + S        I++ +  
Sbjct: 151  EVYRLRSLNDKSKYVQEESYHYQQENQQYLAKIRQLEMQIRDLMSKEDNYIMQINKAAQG 210

Query: 377  NTASKM--KSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISE--KD 432
            N    M  K   +QL  + L      ++ K    +LE + Q  +K L D+   I+   KD
Sbjct: 211  NNNENMILKEQNAQLQQQLL------QLQKQYQKQLEDMSQERDKILSDQRNTINIQIKD 264

Query: 433  TXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNT--EDVNEIAKVQEQLKQ--- 487
                        ++ L+ ++QL  QQ  +    I        E+VN   +   +L+Q   
Sbjct: 265  QLLREQQKWQNEREALLQEIQLLKQQLSQNEQQILRKRQQIEEEVNRNQQYLIELEQGNT 324

Query: 488  ELNDEIKDV-NVKDLIEKLKSAEEQITQLNDE----IDAANKNMIKVKSNHKLKLKQM-Q 541
            +L +  +++ N   L+EK K   +Q T+  DE    +D   + M  + + +   L+Q  Q
Sbjct: 325  QLQNRCRELQNQISLMEKDKHRIDQYTRRIDEQQQQLDQLQRQMYDLTNKYNNLLQQYEQ 384

Query: 542  KTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKK 601
            K   N    S  N     + +E  H  QK+  LE++   LQ  L D    R   + + + 
Sbjct: 385  KKYQNEQLNSQLN-----MVQE--HDKQKIINLEKQIRELQDQLADTQRLRQQLNQMNEN 437

Query: 602  MIEMENLAETRLKAISLLESQKFDLVQELHILQQ-KYDEVEDKLADISQLQSDQVCSEIK 660
               ++   +T  K +   +    +L+Q    L+  K  +V++K  D+ Q +S  +  E +
Sbjct: 438  YTALQLSFKTSQKQLQDFDELNQELIQLQRELEYYKQQDVKNK-QDLDQYKSQLLMIENR 496

Query: 661  -SVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNY-IQENM 718
             +     +++ L    ++L   + NL+   +QL    +  +ND +      QNY + E+ 
Sbjct: 497  QNQQANSELEKLKYQNQQLNDELNNLRNTNQQLTFKFQQAQNDLQS-----QNYALNESN 551

Query: 719  DLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRI 778
             L  K++++  ++I     +IN +++   + Q  +  + Q+ DL I  +E E   ++ RI
Sbjct: 552  QLKAKIKEL-LDQIQYQQIEINKKDKLIQELQIKLQQQNQKIDLII-TMEKERKDFEYRI 609

Query: 779  CRLEESIA---VMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDR 835
             +LE+ +A   + + +   L+ K + L    +  +    EY   + ++V     L D + 
Sbjct: 610  IQLEKQLADSNLYKSQFIELQSKYENLRKDYELLRIKLEEYNNMQQKMVWLEKQLADAN- 668

Query: 836  VVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTK 895
            + + Q LE+E++   L    Q  + + +  Q+  ++M +   A ++      + E+E  K
Sbjct: 669  IYKTQYLELENKYNNLDANYQFKISQLEK-QLQEANMYKMQYAELQNKYNFIIQENEIVK 727

Query: 896  YQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIE 955
                 +D E    ++   +  LI+ KK+    + I+FNT+ ++   + +    K +    
Sbjct: 728  -----KDYEQLRYKLEEVNNQLIISKKQ----ITIQFNTEFDALKSEMQTWILKCKTYEN 778

Query: 956  YVTQLEAQLQEYKNNIENLNMNVE-ELNKMNLELIDKHVQKQQT----QSPDYTEQYINE 1010
             +  L + +++Y++N +N N+ V+ EL +  ++  +   ++QQ     Q  D     IN+
Sbjct: 779  EINFLRSTIKDYQDN-DNENLLVKKELERWQIKCSELERERQQLKLNLQELDKLRYRIND 837

Query: 1011 INKLNALLKQK----DEEIIALNQKI---NNAQVSYMSMVSDYES---KLAQFTTKLENM 1060
            + K N   + K    ++E  A  Q+I      +  Y  +  DY++   +L +   +   +
Sbjct: 838  LEKDNQNYQFKIARLEKEADATRQQIIILEQQRTQYDLIKKDYDALQIRLQEQEREKSQL 897

Query: 1061 EEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEP 1120
              EM  + +QL   +Q   ++Q+L +E++  + +L+E+    E    K + +I+++T   
Sbjct: 898  RNEMDILRQQL---QQFKSQVQMLEQERNQSLMKLEESDR--ERQGLKQQILILNNT--- 949

Query: 1121 MSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLET 1180
               +  N+                +E E F Q+   L  ++  L  +LQ    +  + + 
Sbjct: 950  -KVELENIR---------------REYENFKQKYEQLDRETISLRQQLQILNNQKGEFDR 993

Query: 1181 LNTELTGHDVVNQEQINQ---LKSKLEQLNTENDNLLSTVAE---LRSSISSAVDQRGFE 1234
            +  E +   +  +EQ  +   L+S+L+  + + ++L     E   +R  +  +   +  +
Sbjct: 994  IKVEYSQLKINVEEQDREHLSLRSQLQLASNQKNDLEKFRQEYDIIRIKLEESEKDKN-Q 1052

Query: 1235 IAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKI-VTMEQVT 1293
            +    + ++    A   + EH L +Q+S F+    Q L S Q        +I + ++Q+ 
Sbjct: 1053 VKSQLQVYITNINAYKDQIEH-LNIQISQFQ----QDLSSFQQQEIMMKREIEMLIQQID 1107

Query: 1294 SLQNKLQDKEEHLRNLQEKYADVINQIEILRS-EIEDEKVAFXXXXXXXXXXXXXXXXDL 1352
              +   Q+K++ ++  Q KY +++ + E+L+S ++  +  A                   
Sbjct: 1108 IFKKDQQNKQQQIQEFQFKYQEILREYEVLQSKQVNIDVDALMYEIFELKKQLVQKEKQY 1167

Query: 1353 RTENQSYKQMQEQSILNIN-EENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLEL 1411
              E Q Y + + QS  NI      ++++ +            ++   + + L++  +L L
Sbjct: 1168 EIERQEYLEQKFQSEKNIKLRVEQEIRQITERYNFEREELRKQIQVEKQQKLQIETELRL 1227

Query: 1412 KDSE---IYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHE 1468
            K  +   I QK  +  I +     +   +++Q+V  ++++E L  E+      +RL++ +
Sbjct: 1228 KYEQQILILQKQIKPVIDVDALMYDIFELKKQVVAKDQQLEQLKKEQYQ----MRLQIEQ 1283

Query: 1469 NANHYETMQKESEIERVKLIEELNVKITESVSLN-KQVAELNKALEEEVAKTNEMQTALE 1527
              N  + M+ ESE+ RVKL  EL + I   +    +   + ++ +++ + +  + ++  +
Sbjct: 1284 QFNQ-QRMKFESEL-RVKLERELRMSIESEIRFQIENDYKFDQNIQDYILQVEKWKSVCQ 1341

Query: 1528 NQEIEIVTLNDEITNLQNMVRASSSKIQKHV 1558
             ++ EI    D +  LQ  ++   ++  + +
Sbjct: 1342 MRDEEI----DHMRGLQQALKEKLNQYTQEI 1368



 Score =  109 bits (262), Expect = 6e-22
 Identities = 256/1317 (19%), Positives = 548/1317 (41%), Gaps = 120/1317 (9%)

Query: 168  METTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIA 227
            M  ++ + +E+I  + QII+  N                          Q   +Q++   
Sbjct: 74   MNQSVKEYEEEIQRQKQIIDRLNLDLDKAKRDNEQLLQGFNDIKHRGLSQEQNLQQDNQR 133

Query: 228  MEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSK-LAQ--ELEQXXXX 284
            M+    D     L++++ +  R+ SL + +K ++   +    E+ + LA+  +LE     
Sbjct: 134  MK-HTIDGLNNDLRNLQQEVYRLRSLNDKSKYVQEESYHYQQENQQYLAKIRQLEMQIRD 192

Query: 285  XXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKE 344
                         ++ + +  E   ++E+ +     + +L K+ +  + L    ++ +K 
Sbjct: 193  LMSKEDNYIMQINKAAQGNNNENMILKEQNAQLQQQLLQLQKQYQ--KQLEDMSQERDKI 250

Query: 345  LENKLATMGTESK-AVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLN--QDTDKK 401
            L ++  T+  + K  +    +K      R++       +K   SQ   + L   Q  +++
Sbjct: 251  LSDQRNTINIQIKDQLLREQQKWQN--EREALLQEIQLLKQQLSQNEQQILRKRQQIEEE 308

Query: 402  INKNE--IAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQL-QLEHQQ 458
            +N+N+  + +LE     L     + +  IS  +             D    QL QL+ Q 
Sbjct: 309  VNRNQQYLIELEQGNTQLQNRCRELQNQISLMEKDKHRIDQYTRRIDEQQQQLDQLQRQM 368

Query: 459  HMEGPSLIHVGTNTEDVNEIAKVQ-EQLKQELN-----DEIKDVNVKDLIEKLKSAEEQI 512
            +     L +   N     E  K Q EQL  +LN     D+ K +N++  I +L+      
Sbjct: 369  Y----DLTNKYNNLLQQYEQKKYQNEQLNSQLNMVQEHDKQKIINLEKQIRELQDQLADT 424

Query: 513  TQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVA 572
             +L  +++  N+N   +    +L  K  QK + +F ++   N+E+++L  EL +  Q+  
Sbjct: 425  QRLRQQLNQMNENYTAL----QLSFKTSQKQLQDFDEL---NQELIQLQRELEYYKQQDV 477

Query: 573  ELEE--EKGNLQLHLVDYDSGRMIESDVYKKMI-------EMENLAETRLKAISLLESQK 623
            + ++  ++   QL +++    +   S++ K          E+ NL  T  +     +  +
Sbjct: 478  KNKQDLDQYKSQLLMIENRQNQQANSELEKLKYQNQQLNDELNNLRNTNQQLTFKFQQAQ 537

Query: 624  FDLVQELHILQQKYDEVEDKLAD-ISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVI 682
             DL  + + L +  ++++ K+ + + Q+Q  Q+    K   ++E    L    +++ L+I
Sbjct: 538  NDLQSQNYALNES-NQLKAKIKELLDQIQYQQIEINKKDKLIQELQIKLQQQNQKIDLII 596

Query: 683  ENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHE 742
               K  K+  Y  I+ LE    D  + L  Y  + ++L  K E +   K  ELL +I  E
Sbjct: 597  TMEKERKDFEYRIIQ-LEKQLAD--SNL--YKSQFIELQSKYENL--RKDYELL-RIKLE 648

Query: 743  EQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQL 802
            E +           +Q++ +++E   ++ + YK++   LE     + D  Y    K  QL
Sbjct: 649  EYN----------NMQQKMVWLEKQLADANIYKTQYLELENKYNNL-DANYQF--KISQL 695

Query: 803  GSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEEN 862
               LQE     + Y +Q  EL N+   ++  + +V+K   ++ ++ +E+   NQ+++ + 
Sbjct: 696  EKQLQEA----NMYKMQYAELQNKYNFIIQENEIVKKDYEQLRYKLEEV--NNQLIISKK 749

Query: 863  QNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRI-THEHQTLIVQK 921
               QI++      ++AL  +     L   +   Y+ ++  L S +K    ++++ L+V  
Sbjct: 750  ---QITI-QFNTEFDALKSEMQTWIL---KCKTYENEINFLRSTIKDYQDNDNENLLV-- 800

Query: 922  KKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEEL 981
            KKE+E  +I+  +++E   +  K+  ++ +K    +  LE   Q Y+  I  L     + 
Sbjct: 801  KKELERWQIKC-SELERERQQLKLNLQELDKLRYRINDLEKDNQNYQFKIARLEKEA-DA 858

Query: 982  NKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMS 1041
             +  + ++++   +      DY    I  + +      Q   E+  L Q++      + S
Sbjct: 859  TRQQIIILEQQRTQYDLIKKDYDALQI-RLQEQEREKSQLRNEMDILRQQLQ----QFKS 913

Query: 1042 MVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLT 1101
             V   E +  Q   KLE  + E Q + +Q+L       EL+ + RE ++  ++ ++    
Sbjct: 914  QVQMLEQERNQSLMKLEESDRERQGLKQQILILNNTKVELENIRREYENFKQKYEQL--- 970

Query: 1102 FEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQS 1161
                    E + +   ++ +++     D            ++ +++ E +  RS LQ  S
Sbjct: 971  ------DRETISLRQQLQILNNQKGEFDRIKVEYSQLKINVE-EQDREHLSLRSQLQLAS 1023

Query: 1162 AKLN--TELQECYTKIIQLETLNTELTGHDVVNQEQ-----INQLKSKLEQLNTENDNLL 1214
             + N   + ++ Y  II+++   +E   + V +Q Q     IN  K ++E LN +     
Sbjct: 1024 NQKNDLEKFRQEY-DIIRIKLEESEKDKNQVKSQLQVYITNINAYKDQIEHLNIQ----- 1077

Query: 1215 STVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLD- 1273
              +++ +  +SS   Q      E+  + L Q+   F+K +   + Q+  F+ KY+++L  
Sbjct: 1078 --ISQFQQDLSSFQQQEIMMKREI--EMLIQQIDIFKKDQQNKQQQIQEFQFKYQEILRE 1133

Query: 1274 -SVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIE-ILRSEIEDEK 1331
              V  S Q   +    M ++  L+ +L  KE+     +++Y +   Q E  ++  +E E 
Sbjct: 1134 YEVLQSKQVNIDVDALMYEIFELKKQLVQKEKQYEIERQEYLEQKFQSEKNIKLRVEQE- 1192

Query: 1332 VAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXX 1391
                                ++ E Q   Q++ +  L   ++   L+K            
Sbjct: 1193 --IRQITERYNFEREELRKQIQVEKQQKLQIETELRLKYEQQILILQK-QIKPVIDVDAL 1249

Query: 1392 XXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRI 1448
               + + + +V+    QLE    E YQ   +      Q+  +FE+  +  +E E R+
Sbjct: 1250 MYDIFELKKQVVAKDQQLEQLKKEQYQMRLQIEQQFNQQRMKFESELRVKLERELRM 1306



 Score =  105 bits (253), Expect = 8e-21
 Identities = 189/967 (19%), Positives = 396/967 (40%), Gaps = 85/967 (8%)

Query: 682  IENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEK--ISELLAKI 739
            I+ L+     L   + + +   +D     +   Q N  + +  E++  +K  I  L   +
Sbjct: 40   IQQLQAQLHYLNQKVPEFQQIFKDNQQMKKALDQMNQSVKEYEEEIQRQKQIIDRLNLDL 99

Query: 740  NHEEQSKIQTQFGIDAKIQERDLYIE-NIESELSKYKSRICRLEESIAVMEDRRYSLERK 798
            +  ++   Q   G +  I+ R L  E N++ +  + K  I  L   +  ++   Y L R 
Sbjct: 100  DKAKRDNEQLLQGFN-DIKHRGLSQEQNLQQDNQRMKHTIDGLNNDLRNLQQEVYRL-RS 157

Query: 799  ADQLGSYLQEKQKAYSEYTIQEDELVNRLAV-LMDHDRVVEKQLLEIEHENKELQKKNQI 857
             +    Y+QE+   Y +   Q    + +L + + D     +  +++I    +    +N I
Sbjct: 158  LNDKSKYVQEESYHYQQENQQYLAKIRQLEMQIRDLMSKEDNYIMQINKAAQGNNNENMI 217

Query: 858  LLEENQNLQISLSDMQQHYNALVEKAN--RTDLAESESTKYQTQLRD-LESNLKRITHEH 914
            L E+N  LQ  L  +Q+ Y   +E  +  R  +   +      Q++D L    ++  +E 
Sbjct: 218  LKEQNAQLQQQLLQLQKQYQKQLEDMSQERDKILSDQRNTINIQIKDQLLREQQKWQNER 277

Query: 915  QTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLE---AQLQEYKNNI 971
            + L+    +EI+ L+ + +   +  +R ++ + E+  +N +Y+ +LE    QLQ     +
Sbjct: 278  EALL----QEIQLLKQQLSQNEQQILRKRQQIEEEVNRNQQYLIELEQGNTQLQNRCREL 333

Query: 972  ENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIA---L 1028
            +N  +++ E +K  ++   + + +QQ Q      Q  +  NK N LL+Q +++      L
Sbjct: 334  QN-QISLMEKDKHRIDQYTRRIDEQQQQLDQLQRQMYDLTNKYNNLLQQYEQKKYQNEQL 392

Query: 1029 NQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVS-----------------KQL 1071
            N ++N  Q      + + E ++ +   +L + +   Q+++                 KQL
Sbjct: 393  NSQLNMVQEHDKQKIINLEKQIRELQDQLADTQRLRQQLNQMNENYTALQLSFKTSQKQL 452

Query: 1072 LDSKQHNEELQILVRE------QDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMS--D 1123
             D  + N+EL  L RE      QD + K+  +   +  + I   +    +S +E +   +
Sbjct: 453  QDFDELNQELIQLQRELEYYKQQDVKNKQDLDQYKSQLLMIENRQNQQANSELEKLKYQN 512

Query: 1124 DANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNT 1183
               N +             K Q+ +  +Q ++    +S +L  +++E    + Q++    
Sbjct: 513  QQLNDELNNLRNTNQQLTFKFQQAQNDLQSQNYALNESNQLKAKIKEL---LDQIQYQQI 569

Query: 1184 ELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAE--LWKQ 1241
            E+   D + QE    L+ KL+Q N + D L+ T+ + R      + Q   ++A+  L+K 
Sbjct: 570  EINKKDKLIQE----LQIKLQQQNQKID-LIITMEKERKDFEYRIIQLEKQLADSNLYKS 624

Query: 1242 HLAQREADFQ--KTEHEL-RVQLSAFESKYE-------QLLDSVQSSTQ--EETNKIVTM 1289
               + ++ ++  + ++EL R++L  + +  +       QL D+    TQ  E  NK   +
Sbjct: 625  QFIELQSKYENLRKDYELLRIKLEEYNNMQQKMVWLEKQLADANIYKTQYLELENKYNNL 684

Query: 1290 E-----QVTSLQNKLQDKEEH---LRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXX 1341
            +     +++ L+ +LQ+   +      LQ KY  +I + EI++ + E  +          
Sbjct: 685  DANYQFKISQLEKQLQEANMYKMQYAELQNKYNFIIQENEIVKKDYEQLRYKLEEVNNQL 744

Query: 1342 XXXXXXXXXDLRTENQSYKQMQEQSILNIN--EENAQLKKSSXXXXXXXXXXXXRVNDAE 1399
                        TE  + K   +  IL     E      +S+             V    
Sbjct: 745  IISKKQITIQFNTEFDALKSEMQTWILKCKTYENEINFLRSTIKDYQDNDNENLLVKKEL 804

Query: 1400 AKVLELTHQLELKDSEIYQKTHEYTITLTQRND---EFENVRQQLVEYEKRIEDLTYEKE 1456
             +      +LE +  ++     E      + ND   + +N + ++   EK   D T ++ 
Sbjct: 805  ERWQIKCSELERERQQLKLNLQELDKLRYRINDLEKDNQNYQFKIARLEKEA-DATRQQI 863

Query: 1457 SELAILRLKMHENANHYETMQ---KESEIERVKLIEELNVKITESVSLNKQVAELNKALE 1513
              L   R +       Y+ +Q   +E E E+ +L  E+++   +      QV  L +   
Sbjct: 864  IILEQQRTQYDLIKKDYDALQIRLQEQEREKSQLRNEMDILRQQLQQFKSQVQMLEQERN 923

Query: 1514 EEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDE-QL 1572
            + + K  E     +  + +I+ LN+    L+N+ R   +  QK+     +T   R + Q+
Sbjct: 924  QSLMKLEESDRERQGLKQQILILNNTKVELENIRREYENFKQKYEQLDRETISLRQQLQI 983

Query: 1573 DNTMNKE 1579
             N    E
Sbjct: 984  LNNQKGE 990



 Score = 84.2 bits (199), Expect = 3e-14
 Identities = 112/571 (19%), Positives = 254/571 (44%), Gaps = 46/571 (8%)

Query: 534  KLKLKQMQKTIDNFSKVSDSNK----EIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYD 589
            KL L+++ K     + +   N+    +I RL +E     Q++  LE+++    L   DYD
Sbjct: 822  KLNLQELDKLRYRINDLEKDNQNYQFKIARLEKEADATRQQIIILEQQRTQYDLIKKDYD 881

Query: 590  SGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQ 649
            + ++   +  ++  ++ N  +   + +   +SQ   L QE +    K +E + +   + Q
Sbjct: 882  ALQIRLQEQEREKSQLRNEMDILRQQLQQFKSQVQMLEQERNQSLMKLEESDRERQGLKQ 941

Query: 650  --LQSDQVCSEIKSVHLE--------EQIDALSASKKELALVIENLKLDKEQL---YGTI 696
              L  +    E++++  E        EQ+D  + S ++   ++ N K + +++   Y  +
Sbjct: 942  QILILNNTKVELENIRREYENFKQKYEQLDRETISLRQQLQILNNQKGEFDRIKVEYSQL 1001

Query: 697  KDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAK 756
            K    +++     L++ +Q   +  + LEK   E    +  K+   E+ K Q +  +   
Sbjct: 1002 KINVEEQDREHLSLRSQLQLASNQKNDLEKFRQE-YDIIRIKLEESEKDKNQVKSQLQVY 1060

Query: 757  IQERDLY---IENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAY 813
            I   + Y   IE++  ++S+++  +   ++   +M+     L ++ D      Q KQ+  
Sbjct: 1061 ITNINAYKDQIEHLNIQISQFQQDLSSFQQQEIMMKREIEMLIQQIDIFKKDQQNKQQQI 1120

Query: 814  SEYTIQEDELVNRLAVLMDHDRVVEKQLL--EIEHENKEL-QKKNQILLEENQNLQISLS 870
             E+  +  E++    VL      ++   L  EI    K+L QK+ Q  +E  + L+    
Sbjct: 1121 QEFQFKYQEILREYEVLQSKQVNIDVDALMYEIFELKKQLVQKEKQYEIERQEYLEQKFQ 1180

Query: 871  D-------MQQHYNALVEKAN--RTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQK 921
                    ++Q    + E+ N  R +L +    + Q +L+ +E+ L R+ +E Q LI+QK
Sbjct: 1181 SEKNIKLRVEQEIRQITERYNFEREELRKQIQVEKQQKLQ-IETEL-RLKYEQQILILQK 1238

Query: 922  K-KEIEDLEI----EFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIEN-LN 975
            + K + D++      F  + +   +D++ L +  ++  +   Q+E Q  + +   E+ L 
Sbjct: 1239 QIKPVIDVDALMYDIFELKKQVVAKDQQ-LEQLKKEQYQMRLQIEQQFNQQRMKFESELR 1297

Query: 976  MNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNA 1035
            + +E   +M++E   +   +   +     + YI ++ K  ++ + +DEEI      +   
Sbjct: 1298 VKLERELRMSIESEIRFQIENDYKFDQNIQDYILQVEKWKSVCQMRDEEI----DHMRGL 1353

Query: 1036 QVSYMSMVSDYESKLAQFTTKLENMEEEMQR 1066
            Q +    ++ Y  ++    T+L   + E ++
Sbjct: 1354 QQALKEKLNQYTQEIESLKTQLSMFQGERKK 1384


>UniRef50_UPI0000E476CA Cluster: PREDICTED: similar to KIAA0445
            protein; n=6; Deuterostomia|Rep: PREDICTED: similar to
            KIAA0445 protein - Strongylocentrotus purpuratus
          Length = 2435

 Score =  136 bits (329), Expect = 5e-30
 Identities = 255/1263 (20%), Positives = 527/1263 (41%), Gaps = 113/1263 (8%)

Query: 358  AVSSPSKKGSPLISRKSGRNTAS--KMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQ 415
            +++SP  K +PL      R TAS  + +SP    S+ +  Q   +K  + ++ +L+  + 
Sbjct: 499  SLASPYAKSTPLRPVTPSRRTASPSRARSPGFPDSTYSAVQAALQK-RQLQVQELKARLN 557

Query: 416  SLNKDL--VDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTE 473
            S       + K    SE +             +  ++Q QLE  +         +  + E
Sbjct: 558  STRDQASTLKKNLEGSENERRQTERAVDAHRDNLSVSQRQLEEIKRDRD----RLRNSLE 613

Query: 474  DVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNH 533
                     E L+Q LN +I+ +NV++  E+L++A   + +  D ++   ++  K     
Sbjct: 614  ATGSEKSGLENLRQSLNAQIESLNVEN--ERLQAANSDLQRQRDHLEDEREDREKDSIRQ 671

Query: 534  KLKLKQMQKTIDNFS-KVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGR 592
            K ++++  K ++    K S+  ++IV L E L+    +   LE+EK  +   L   +  R
Sbjct: 672  KKEIERSHKLLEQMEGKNSNLKEDIVTLKEALNKAVLEKDVLEQEKAEISESLARLEVQR 731

Query: 593  M-IESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQ 651
              +E ++ +   E   L ++ LK  +L E    D ++   I+ Q   E    + D   + 
Sbjct: 732  AELEVELNRLRTEEAGLRDSLLKMQALNEGLGQDKIELNKIIMQLEAEKNRLIEDKDNIH 791

Query: 652  SDQVCSEIKSVHLE-EQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKL 710
             ++     + + +E E++D             E  K+   Q    ++D     E+ M+ L
Sbjct: 792  HERAAIRDELMRVESEKVDT------------ETEKMGLNQSLSLMEDNRTRLEEEMSLL 839

Query: 711  QNYIQENMDLTDKLEKMSAEK--ISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIE 768
                +E  +L D L ++S +K  ++E L +   + + +I+    I  + +E       + 
Sbjct: 840  N---REKGELGDNLSQLSRQKNSLAEELLQTRRDVERQIEAVTRIAKEKEELTKEKAELI 896

Query: 769  SELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDEL----V 824
             +L+  +       E IA M   + SLER    L  Y Q   K  ++ T  E EL    V
Sbjct: 897  VQLTASERENRAQAEVIAAMNTDKESLERT---LYEYQQSLAKLEAKRTQLESELQEQGV 953

Query: 825  NRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKAN 884
            ++  V ++  R  ++  +E+    K+L+  NQ ++++ ++ Q++L   QQ ++  VE+ N
Sbjct: 954  SKEGVTVELARQRKEMEIEMTRYQKDLELLNQRMVQQERDTQLALKQRQQAHDEDVERLN 1013

Query: 885  RTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKK 944
            R  ++ES   + + Q  +LE  L R+  E   L         D  ++     E   +DK 
Sbjct: 1014 RERVSES-LARLEVQRAELEVELNRLRTEEAGL--------RDSLLKMQALNEGLGQDKI 1064

Query: 945  VLNEKYEKNIEYVTQLEAQ---LQEYKNNIENLNMNV-EELNKMNLELIDKHVQKQQTQS 1000
             LN       + + QLEA+   L E K+NI +    + +EL ++  E +D   +K     
Sbjct: 1065 ELN-------KIIMQLEAEKNRLIEDKDNIHHERAAIRDELMRVESEKVDTETEKMGLNQ 1117

Query: 1001 PDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENM 1060
                   + E N+      + +EE+  LN++             +    L+Q + +  ++
Sbjct: 1118 ----SLSLMEDNR-----TRLEEEMSLLNRE-----------KGELGDNLSQLSRQKNSL 1157

Query: 1061 EEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEP 1120
             EE+ +  +   D ++  E +  + +E+++  KE  + +L  ++   + E    +  I  
Sbjct: 1158 AEELLQTRR---DVERQIEAVTRIAKEKEELTKE--KAELIVQLTASERENRAQAEVIAA 1212

Query: 1121 MSDDANNVDXXXXXXXXXXXXLKVQ--EEEEFIQERSVLQE-QSAKLNTELQECYTKIIQ 1177
            M+ D  +++            L+ +  + E  +QE+ V +E  + +L  + +E   ++ +
Sbjct: 1213 MNTDKESLERTLYEYQQSLAKLEAKRTQLESELQEQGVSKEGVTVELARQRKEMEIEMTR 1272

Query: 1178 LETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAE 1237
             +  + EL    +V QE+  QL   L+Q    +D  +  +   R S+  A++    ++  
Sbjct: 1273 YQK-DLELLNQRMVQQERDTQL--ALKQRQQAHDEDVERLNRERESLKLAMEAEKEDLVR 1329

Query: 1238 LWKQHLAQREADFQKTEHELRVQLSAFESKYEQLL-----DSVQSSTQEETNKIVTMEQV 1292
               Q   +    + + + EL   L   + + ++ L     D  QS +  +T +   +E++
Sbjct: 1330 KTNQEREELNGRYMQEKEELTEDLMGLQRERDESLLLAENDKQQSLSLAQTERNQLVEKL 1389

Query: 1293 TSLQNKLQDKEEHL-RNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXD 1351
             S Q  + +    + R  +E +       E +R +++DE                    D
Sbjct: 1390 NSSQRDMANASMEMDRIKREAFTRAETDKEAIR-DVQDELKELRARFEEGTNVRERQAKD 1448

Query: 1352 LRTENQSYKQMQEQSILNINEENAQLK---KSSXXXXXXXXXXXXRVNDA-EAKVLELTH 1407
            L  + +  ++++E  +  +NE   QLK   +S             ++ +  E + ++   
Sbjct: 1449 LSNQIKDLQKVKEALLREVNELKTQLKMAEESRDGVRRELIEAHRKIREGDEGREIQRKE 1508

Query: 1408 QLELK---DSEIYQK--THEYTITLTQRNDEFENVRQQL-VEYEKRIEDLTYEKESELAI 1461
             +ELK   + E+ +K   +     L Q+  + E  R QL    E+R + +   +ES+ AI
Sbjct: 1509 NMELKRQMNDEVREKDAINRANEELRQKVKKVETDRIQLNRNVEERTQKIAVLEESKTAI 1568

Query: 1462 LRL--KMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNK--ALEEEVA 1517
             +    +  +    E  + E+  E  +L  ++    T+   L K + +L    A ++E  
Sbjct: 1569 QKEAGDLRASLREVEKSRLEARRELQELRRQVKTLDTDKAKLTKDIHDLQNRVARDDEKE 1628

Query: 1518 KTNEMQT-ALENQEI--EIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDN 1574
            + N  +  AL+ +    +   L     +L+  +R         V  A   ++   E+L  
Sbjct: 1629 EENRKEIYALKQKSARKDAQNLTRRFGDLEEELRLKEKDYAMSVDEARSAERRISERLRT 1688

Query: 1575 TMN 1577
            T N
Sbjct: 1689 TEN 1691



 Score =  122 bits (294), Expect = 8e-26
 Identities = 219/1072 (20%), Positives = 468/1072 (43%), Gaps = 97/1072 (9%)

Query: 297  KQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTES 356
            + S+E +  EK+ +E       A +  L  + E L+  N  +++    LE++      +S
Sbjct: 609  RNSLEATGSEKSGLENLRQSLNAQIESLNVENERLQAANSDLQRQRDHLEDEREDREKDS 668

Query: 357  KAVSSPSKKGSPLISRKSGRNTASK-----MKSPWSQ--LSSETLNQ---DTDKKINKNE 406
                   ++   L+ +  G+N+  K     +K   ++  L  + L Q   +  + + + E
Sbjct: 669  IRQKKEIERSHKLLEQMEGKNSNLKEDIVTLKEALNKAVLEKDVLEQEKAEISESLARLE 728

Query: 407  I--AKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPS 464
            +  A+LE+ +  L  +       + +               + +I QL+ E  + +E   
Sbjct: 729  VQRAELEVELNRLRTEEAGLRDSLLKMQALNEGLGQDKIELNKIIMQLEAEKNRLIEDKD 788

Query: 465  LIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVK-DLIEKLKSAEEQITQLNDEIDAAN 523
             IH        +E A ++++L +  ++++     K  L + L   E+  T+L +E+   N
Sbjct: 789  NIH--------HERAAIRDELMRVESEKVDTETEKMGLNQSLSLMEDNRTRLEEEMSLLN 840

Query: 524  KNMIKVKSNHKLKLKQMQKTIDNFS-KVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQ 582
            +   ++  N    L Q+ +  ++ + ++  + +++ R  E +  ++++  EL +EK  L 
Sbjct: 841  REKGELGDN----LSQLSRQKNSLAEELLQTRRDVERQIEAVTRIAKEKEELTKEKAELI 896

Query: 583  LHLVDYDSGRMIESDVYKKM-IEMENLAETRL---KAISLLESQKFDLVQELHILQQKYD 638
            + L   +     +++V   M  + E+L  T     ++++ LE+++  L  EL       +
Sbjct: 897  VQLTASERENRAQAEVIAAMNTDKESLERTLYEYQQSLAKLEAKRTQLESELQEQGVSKE 956

Query: 639  EVEDKLA--------DISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKE 690
             V  +LA        ++++ Q D      + V  +E+   L+  +++ A   +  +L++E
Sbjct: 957  GVTVELARQRKEMEIEMTRYQKDLELLNQRMVQ-QERDTQLALKQRQQAHDEDVERLNRE 1015

Query: 691  QLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSA-------EKI--SELLAKINH 741
            ++  ++  LE  + ++  +L     E   L D L KM A       +KI  ++++ ++  
Sbjct: 1016 RVSESLARLEVQRAELEVELNRLRTEEAGLRDSLLKMQALNEGLGQDKIELNKIIMQLEA 1075

Query: 742  EEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQ 801
            E+   I+ +  I  +       +  +ESE    ++    L +S+++MED R  LE +   
Sbjct: 1076 EKNRLIEDKDNIHHERAAIRDELMRVESEKVDTETEKMGLNQSLSLMEDNRTRLEEEMSL 1135

Query: 802  LGSYLQEKQKAYSEYTIQEDELVNR-LAVLMDHDRVVEKQLLEIEHENKELQKKNQILLE 860
            L     E     S+ + Q++ L    L    D +R +E  +  I  E +EL K+   L+ 
Sbjct: 1136 LNREKGELGDNLSQLSRQKNSLAEELLQTRRDVERQIE-AVTRIAKEKEELTKEKAELI- 1193

Query: 861  ENQNLQISLSDMQQHYNALVEKANRTDLAESEST--KYQTQLRDLESNLKRITHEHQTLI 918
                +Q++ S+ +    A V  A  TD    E T  +YQ  L  LE+   ++  E Q   
Sbjct: 1194 ----VQLTASERENRAQAEVIAAMNTDKESLERTLYEYQQSLAKLEAKRTQLESELQEQG 1249

Query: 919  VQKK---KEIEDLEIEFNTQIESAIRDKKVLNEK-YEKNIEYVTQLEAQLQEYKNNIENL 974
            V K+    E+     E   ++    +D ++LN++  ++  +    L+ + Q +  ++E L
Sbjct: 1250 VSKEGVTVELARQRKEMEIEMTRYQKDLELLNQRMVQQERDTQLALKQRQQAHDEDVERL 1309

Query: 975  NMNVEELNKMNLE-----LIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEE-IIAL 1028
            N   E L K+ +E     L+ K  Q+++  +  Y ++       L  L +++DE  ++A 
Sbjct: 1310 NRERESL-KLAMEAEKEDLVRKTNQEREELNGRYMQEKEELTEDLMGLQRERDESLLLAE 1368

Query: 1029 NQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQ 1088
            N K  +  ++     +    KL      + N   EM R+ ++     + ++E    +R+ 
Sbjct: 1369 NDKQQSLSLAQTER-NQLVEKLNSSQRDMANASMEMDRIKREAFTRAETDKE---AIRDV 1424

Query: 1089 DDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEE 1148
             D++KEL+  +     N+ + +   +S+ I+    D   V               ++E  
Sbjct: 1425 QDELKELR-ARFEEGTNVRERQAKDLSNQIK----DLQKVKEAL-----------LREVN 1468

Query: 1149 EFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNT 1208
            E   +  + +E    +  EL E + KI + +         ++  + Q+N    + + +N 
Sbjct: 1469 ELKTQLKMAEESRDGVRRELIEAHRKIREGDEGREIQRKENMELKRQMNDEVREKDAINR 1528

Query: 1209 ENDNLLSTVAEL---RSSISSAVDQRGFEIAELWKQHLA-QREA-DFQKTEHELRVQLSA 1263
             N+ L   V ++   R  ++  V++R  +IA L +   A Q+EA D + +  E  V+ S 
Sbjct: 1529 ANEELRQKVKKVETDRIQLNRNVEERTQKIAVLEESKTAIQKEAGDLRASLRE--VEKSR 1586

Query: 1264 FESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKL-QDKEEHLRNLQEKYA 1314
             E++ E L +  +     +T+K    + +  LQN++ +D E+   N +E YA
Sbjct: 1587 LEARRE-LQELRRQVKTLDTDKAKLTKDIHDLQNRVARDDEKEEENRKEIYA 1637



 Score =  115 bits (277), Expect = 9e-24
 Identities = 185/1031 (17%), Positives = 429/1031 (41%), Gaps = 76/1031 (7%)

Query: 619  LESQKFDLVQEL-HILQQKYDEVEDKLADISQLQ-SDQVCSEI--KSVHLEEQIDALSAS 674
            L++   DL ++  H+  ++ D  +D +    +++ S ++  ++  K+ +L+E I  L  +
Sbjct: 643  LQAANSDLQRQRDHLEDEREDREKDSIRQKKEIERSHKLLEQMEGKNSNLKEDIVTLKEA 702

Query: 675  KKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSA----- 729
              +  L  + L+ +K ++  ++  LE  + ++  +L     E   L D L KM A     
Sbjct: 703  LNKAVLEKDVLEQEKAEISESLARLEVQRAELEVELNRLRTEEAGLRDSLLKMQALNEGL 762

Query: 730  --EKI--SELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESI 785
              +KI  ++++ ++  E+   I+ +  I  +       +  +ESE    ++    L +S+
Sbjct: 763  GQDKIELNKIIMQLEAEKNRLIEDKDNIHHERAAIRDELMRVESEKVDTETEKMGLNQSL 822

Query: 786  AVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLA-VLMDHDRVVEKQLLEI 844
            ++MED R  LE +   L     E     S+ + Q++ L   L     D +R +E  +  I
Sbjct: 823  SLMEDNRTRLEEEMSLLNREKGELGDNLSQLSRQKNSLAEELLQTRRDVERQIEA-VTRI 881

Query: 845  EHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESEST--KYQTQLRD 902
              E +EL K+   L+     +Q++ S+ +    A V  A  TD    E T  +YQ  L  
Sbjct: 882  AKEKEELTKEKAELI-----VQLTASERENRAQAEVIAAMNTDKESLERTLYEYQQSLAK 936

Query: 903  LESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEA 962
            LE+   ++  E Q   V K    E + +E   Q     ++ ++   +Y+K++E + Q   
Sbjct: 937  LEAKRTQLESELQEQGVSK----EGVTVELARQR----KEMEIEMTRYQKDLELLNQRMV 988

Query: 963  QLQEYKNNI---ENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLK 1019
            Q QE    +   +    + E++ ++N E + + + + + Q  +  E  +N +    A L+
Sbjct: 989  Q-QERDTQLALKQRQQAHDEDVERLNRERVSESLARLEVQRAEL-EVELNRLRTEEAGLR 1046

Query: 1020 QKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLL--DSKQH 1077
                ++ ALN+ +   ++    ++   E++  +     +N+  E   +  +L+  +S++ 
Sbjct: 1047 DSLLKMQALNEGLGQDKIELNKIIMQLEAEKNRLIEDKDNIHHERAAIRDELMRVESEKV 1106

Query: 1078 NEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXX 1137
            + E + +   Q   + E   T+L  EM++   E   +   +  +S   N++         
Sbjct: 1107 DTETEKMGLNQSLSLMEDNRTRLEEEMSLLNREKGELGDNLSQLSRQKNSL-AEELLQTR 1165

Query: 1138 XXXXLKVQEEEEFIQERSVLQEQSAKLNTEL------QECYTKIIQLETLNTELTGHDVV 1191
                 +++      +E+  L ++ A+L  +L           ++I     + E     + 
Sbjct: 1166 RDVERQIEAVTRIAKEKEELTKEKAELIVQLTASERENRAQAEVIAAMNTDKESLERTLY 1225

Query: 1192 NQEQI--------NQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHL 1243
              +Q          QL+S+L++     + +   +A  R  +   + +   ++ EL  Q +
Sbjct: 1226 EYQQSLAKLEAKRTQLESELQEQGVSKEGVTVELARQRKEMEIEMTRYQKDL-ELLNQRM 1284

Query: 1244 AQREADFQKTEHELRVQLSAFESKYEQL---LDSVQSSTQEETNKIV--TMEQVTSLQNK 1298
             Q+E D   T+  L+ +  A +   E+L    +S++ + + E   +V  T ++   L  +
Sbjct: 1285 VQQERD---TQLALKQRQQAHDEDVERLNRERESLKLAMEAEKEDLVRKTNQEREELNGR 1341

Query: 1299 -LQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQ 1357
             +Q+KEE   +L     +    + +  ++ +                      D+   + 
Sbjct: 1342 YMQEKEELTEDLMGLQRERDESLLLAENDKQQSLSLAQTERNQLVEKLNSSQRDMANASM 1401

Query: 1358 SYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQ---LELKDS 1414
               +++ ++      +   ++                 N  E +  +L++Q   L+    
Sbjct: 1402 EMDRIKREAFTRAETDKEAIRDVQDELKELRARFEEGTNVRERQAKDLSNQIKDLQKVKE 1461

Query: 1415 EIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKE---SELAILRLKMHENAN 1471
             + ++ +E    L    +  + VR++L+E  ++I +    +E    E   L+ +M++   
Sbjct: 1462 ALLREVNELKTQLKMAEESRDGVRRELIEAHRKIREGDEGREIQRKENMELKRQMNDEVR 1521

Query: 1472 HYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEI 1531
              + + + +E  R K ++++    T+ + LN+ V E      +++A   E +TA++ +  
Sbjct: 1522 EKDAINRANEELRQK-VKKVE---TDRIQLNRNVEERT----QKIAVLEESKTAIQKEAG 1573

Query: 1532 EIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDL 1591
            ++     E+   +   R    ++++ V      K    + + +  N+   D     E   
Sbjct: 1574 DLRASLREVEKSRLEARRELQELRRQVKTLDTDKAKLTKDIHDLQNRVARDDEKEEENRK 1633

Query: 1592 AMYMLHQRDVR 1602
             +Y L Q+  R
Sbjct: 1634 EIYALKQKSAR 1644



 Score =  113 bits (272), Expect = 4e-23
 Identities = 191/972 (19%), Positives = 402/972 (41%), Gaps = 67/972 (6%)

Query: 669  DALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMS 728
            D LS S+++L    E +K D+++L  +++   ++K  + N  Q+   +   L  + E++ 
Sbjct: 589  DNLSVSQRQL----EEIKRDRDRLRNSLEATGSEKSGLENLRQSLNAQIESLNVENERLQ 644

Query: 729  AEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVM 788
            A   S+L  + +H E  +   +   D+  Q+++  IE     L + + +   L+E I  +
Sbjct: 645  AAN-SDLQRQRDHLEDEREDREK--DSIRQKKE--IERSHKLLEQMEGKNSNLKEDIVTL 699

Query: 789  EDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHEN 848
            ++       + D L     E  ++ +   +Q  EL   L  L   +  +   LL+++  N
Sbjct: 700  KEALNKAVLEKDVLEQEKAEISESLARLEVQRAELEVELNRLRTEEAGLRDSLLKMQALN 759

Query: 849  KEL-QKK---NQIL--LEENQNLQISLSDMQQHYNALVE------KANRTDLAESESTKY 896
            + L Q K   N+I+  LE  +N  I   D   H  A +       ++ + D  E+E    
Sbjct: 760  EGLGQDKIELNKIIMQLEAEKNRLIEDKDNIHHERAAIRDELMRVESEKVD-TETEKMGL 818

Query: 897  QTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEY 956
               L  +E N  R+  E  +L+ ++K E+ D   + + Q  S   +        E+ IE 
Sbjct: 819  NQSLSLMEDNRTRL-EEEMSLLNREKGELGDNLSQLSRQKNSLAEELLQTRRDVERQIEA 877

Query: 957  VTQLEAQLQEYKNNIENLNMNV---EELNKMNLELIDK-HVQKQQTQSPDYTEQYINEIN 1012
            VT++  + +E       L + +   E  N+   E+I   +  K+  +   Y  +Y   + 
Sbjct: 878  VTRIAKEKEELTKEKAELIVQLTASERENRAQAEVIAAMNTDKESLERTLY--EYQQSLA 935

Query: 1013 KLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEM---QRVSK 1069
            KL A   Q + E+           V       + E ++ ++   LE + + M   +R ++
Sbjct: 936  KLEAKRTQLESELQEQGVSKEGVTVELARQRKEMEIEMTRYQKDLELLNQRMVQQERDTQ 995

Query: 1070 QLLDSKQ--HNEELQILVREQDDQIK---ELKETKLTFEMNIPKTEGMIISSTIEPMSDD 1124
              L  +Q  H+E+++ L RE+  +     E++  +L  E+N  +TE   +  ++  M   
Sbjct: 996  LALKQRQQAHDEDVERLNRERVSESLARLEVQRAELEVELNRLRTEEAGLRDSLLKMQAL 1055

Query: 1125 ANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTE 1184
               +             L+  E+   I+++  +  + A +  EL    ++ +  ET    
Sbjct: 1056 NEGLGQDKIELNKIIMQLEA-EKNRLIEDKDNIHHERAAIRDELMRVESEKVDTETEKMG 1114

Query: 1185 LTGHDVVNQEQINQLKSKLEQLNTENDNL---LSTVAELRSSISSAVDQRGFEIAELWKQ 1241
            L     + ++   +L+ ++  LN E   L   LS ++  ++S++  + Q   ++    + 
Sbjct: 1115 LNQSLSLMEDNRTRLEEEMSLLNREKGELGDNLSQLSRQKNSLAEELLQTRRDVERQIEA 1174

Query: 1242 --HLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKL 1299
               +A+ + +  K + EL VQL+A E +     + + +   ++ +   T+ +      KL
Sbjct: 1175 VTRIAKEKEELTKEKAELIVQLTASERENRAQAEVIAAMNTDKESLERTLYEYQQSLAKL 1234

Query: 1300 QDKEEHLRN-LQEKYAD---VINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTE 1355
            + K   L + LQE+      V  ++   R E+E E   +                D +  
Sbjct: 1235 EAKRTQLESELQEQGVSKEGVTVELARQRKEMEIEMTRYQKDLELLNQRMVQQERDTQLA 1294

Query: 1356 NQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDA-EAKVLELTHQLELKDS 1414
             +  +Q  ++ +  +N E   LK +             +  +    + ++   +L  +D 
Sbjct: 1295 LKQRQQAHDEDVERLNRERESLKLAMEAEKEDLVRKTNQEREELNGRYMQEKEELT-EDL 1353

Query: 1415 EIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKM----HENA 1470
               Q+  + ++ L + ND+ +++     E  + +E L    + ++A   ++M     E  
Sbjct: 1354 MGLQRERDESLLLAE-NDKQQSLSLAQTERNQLVEKLN-SSQRDMANASMEMDRIKREAF 1411

Query: 1471 NHYET-------MQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQ 1523
               ET       +Q E +  R +  E  NV+  ++  L+ Q+ +L K  E  + + NE++
Sbjct: 1412 TRAETDKEAIRDVQDELKELRARFEEGTNVRERQAKDLSNQIKDLQKVKEALLREVNELK 1471

Query: 1524 TALENQEIEIVTLNDEITNLQNMVRASSS--KIQKHVSFASDTKQG---RDEQLDNTMNK 1578
            T L+  E     +  E+      +R      +IQ+  +     +     R++   N  N+
Sbjct: 1472 TQLKMAEESRDGVRRELIEAHRKIREGDEGREIQRKENMELKRQMNDEVREKDAINRANE 1531

Query: 1579 ELLDAVPRAELD 1590
            EL   V + E D
Sbjct: 1532 ELRQKVKKVETD 1543



 Score = 91.5 bits (217), Expect = 2e-16
 Identities = 181/907 (19%), Positives = 388/907 (42%), Gaps = 84/907 (9%)

Query: 212  EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271
            E  K ++ + ++N     A  +DE  R+  +    +     L ++  L+E  R  +  E 
Sbjct: 777  EAEKNRLIEDKDNIHHERAAIRDELMRVESEKVDTETEKMGLNQSLSLMEDNRTRLEEEM 836

Query: 272  SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTK-KIEL 330
            S L +E  +              LA++ ++   + + +IE    +      ELTK K EL
Sbjct: 837  SLLNREKGELGDNLSQLSRQKNSLAEELLQTRRDVERQIEAVTRI-AKEKEELTKEKAEL 895

Query: 331  LEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLS 390
            +  L    R+   + E  +A M T+ +++           +    + + +K+++  +QL 
Sbjct: 896  IVQLTASERENRAQAE-VIAAMNTDKESLER---------TLYEYQQSLAKLEAKRTQLE 945

Query: 391  SETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIA 450
            SE   Q   K     E   +E+  Q    ++    Y   +KD            +DT +A
Sbjct: 946  SELQEQGVSK-----EGVTVELARQRKEMEIEMTRY---QKDLELLNQRMVQQERDTQLA 997

Query: 451  QLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELND-EIKDVNVKDLIEKLKSAE 509
             L+   Q H E    ++    +E +  +   + +L+ ELN    ++  ++D + K+++  
Sbjct: 998  -LKQRQQAHDEDVERLNRERVSESLARLEVQRAELEVELNRLRTEEAGLRDSLLKMQALN 1056

Query: 510  EQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQ 569
            E + Q  D+I+  NK ++++++     ++         + + D   E++R+       S+
Sbjct: 1057 EGLGQ--DKIE-LNKIIMQLEAEKNRLIEDKDNIHHERAAIRD---ELMRVE------SE 1104

Query: 570  KVAELEEEKG-NLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQ 628
            KV    E+ G N  L L++ D+   +E ++     E   L +     +S L  QK  L +
Sbjct: 1105 KVDTETEKMGLNQSLSLME-DNRTRLEEEMSLLNREKGELGDN----LSQLSRQKNSLAE 1159

Query: 629  ELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLD 688
            EL  LQ + D VE ++  ++++  ++     +   L  Q+ A     +  A VI  +  D
Sbjct: 1160 EL--LQTRRD-VERQIEAVTRIAKEKEELTKEKAELIVQLTASERENRAQAEVIAAMNTD 1216

Query: 689  KEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQ 748
            KE L  T+ + +     +  K      E  +     + +S E ++  LA+   E + ++ 
Sbjct: 1217 KESLERTLYEYQQSLAKLEAKRTQLESELQE-----QGVSKEGVTVELARQRKEMEIEM- 1270

Query: 749  TQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLE-----RKADQLG 803
            T++  D ++  + +  +  +++L+  K R    +E +  +   R SL+      K D + 
Sbjct: 1271 TRYQKDLELLNQRMVQQERDTQLA-LKQRQQAHDEDVERLNRERESLKLAMEAEKEDLVR 1329

Query: 804  SYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQ 863
               QE+++    Y  +++EL      LM   R  ++ LL    EN + Q  +    E NQ
Sbjct: 1330 KTNQEREELNGRYMQEKEELTED---LMGLQRERDESLLLA--ENDKQQSLSLAQTERNQ 1384

Query: 864  NLQISLSDMQQHYNALVE--KANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQK 921
             ++   S  +   NA +E  +  R     +E+ K    +RD++  LK +    +     +
Sbjct: 1385 LVEKLNSSQRDMANASMEMDRIKREAFTRAETDK--EAIRDVQDELKELRARFEEGTNVR 1442

Query: 922  KKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEEL 981
            +++ +DL    + QI+   + K+ L       +  V +L+ QL+  + + + +   + E 
Sbjct: 1443 ERQAKDL----SNQIKDLQKVKEAL-------LREVNELKTQLKMAEESRDGVRRELIEA 1491

Query: 982  NKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMS 1041
            ++  +   D+  + Q+ ++ +   Q  +E+ + +A+ +  +E    L QK+   +   + 
Sbjct: 1492 HR-KIREGDEGREIQRKENMELKRQMNDEVREKDAINRANEE----LRQKVKKVETDRIQ 1546

Query: 1042 MVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLT 1101
            +  + E +    T K+  +EE    + K+  D +    E++    E   +++EL+    T
Sbjct: 1547 LNRNVEER----TQKIAVLEESKTAIQKEAGDLRASLREVEKSRLEARRELQELRRQVKT 1602

Query: 1102 FEMNIPK 1108
             + +  K
Sbjct: 1603 LDTDKAK 1609



 Score = 78.2 bits (184), Expect = 2e-12
 Identities = 159/887 (17%), Positives = 377/887 (42%), Gaps = 77/887 (8%)

Query: 235  EKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXX 294
            EK+ L K+     V++++ E  N+        ++ +   L + L +              
Sbjct: 884  EKEELTKEKAELIVQLTASERENRAQAEVIAAMNTDKESLERTLYEYQQSLAKLEAKRTQ 943

Query: 295  LAKQSIEPSC-EEKTEIE---EKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLA 350
            L  +  E    +E   +E   ++  +EI  MT   K +ELL       R   +E + +LA
Sbjct: 944  LESELQEQGVSKEGVTVELARQRKEMEI-EMTRYQKDLELLNQ-----RMVQQERDTQLA 997

Query: 351  TMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKL 410
                  K       +    ++R+    + ++++   ++L  E     T++   ++ + K+
Sbjct: 998  L-----KQRQQAHDEDVERLNRERVSESLARLEVQRAELEVELNRLRTEEAGLRDSLLKM 1052

Query: 411  EMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGT 470
            + + + L +D ++   +I + +            KD +  +      + M   S   V T
Sbjct: 1053 QALNEGLGQDKIELNKIIMQLEAEKNRLIED---KDNIHHERAAIRDELMRVESE-KVDT 1108

Query: 471  NTEDV--NEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIK 528
             TE +  N+   + E  +  L +E+  +N      +     + ++QL+ + ++  + +++
Sbjct: 1109 ETEKMGLNQSLSLMEDNRTRLEEEMSLLN-----REKGELGDNLSQLSRQKNSLAEELLQ 1163

Query: 529  VKSNHKLKLKQMQKTIDNFSKVSDSNKE-IVRLT---EELHHLSQKVAELEEEKGNLQLH 584
             + + + +++ + +      +++    E IV+LT    E    ++ +A +  +K +L+  
Sbjct: 1164 TRRDVERQIEAVTRIAKEKEELTKEKAELIVQLTASERENRAQAEVIAAMNTDKESLERT 1223

Query: 585  LVDYDSG-RMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDK 643
            L +Y      +E+   +   E++    ++      L  Q+ ++  E+   Q+  + +  +
Sbjct: 1224 LYEYQQSLAKLEAKRTQLESELQEQGVSKEGVTVELARQRKEMEIEMTRYQKDLELLNQR 1283

Query: 644  LADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDK 703
            +  + Q +  Q+  + +    +E ++ L+  ++ L L +E    +KE L   ++    ++
Sbjct: 1284 M--VQQERDTQLALKQRQQAHDEDVERLNRERESLKLAME---AEKEDL---VRKTNQER 1335

Query: 704  EDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSK--IQTQFG-IDAKIQER 760
            E++  +   Y+QE  +LT+ L  +  E+   LL   N ++QS    QT+   +  K+   
Sbjct: 1336 EELNGR---YMQEKEELTEDLMGLQRERDESLLLAENDKQQSLSLAQTERNQLVEKLNSS 1392

Query: 761  DLYIENIESELSKYKSR-ICRLE---ESIAVMEDRRYSL-----------ERKADQLGSY 805
               + N   E+ + K     R E   E+I  ++D    L           ER+A  L + 
Sbjct: 1393 QRDMANASMEMDRIKREAFTRAETDKEAIRDVQDELKELRARFEEGTNVRERQAKDLSNQ 1452

Query: 806  LQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNL 865
            +++ QK       + +EL  +L +  +    V ++L+E   + +E  +  +I  +EN  L
Sbjct: 1453 IKDLQKVKEALLREVNELKTQLKMAEESRDGVRRELIEAHRKIREGDEGREIQRKENMEL 1512

Query: 866  QISLSDMQQHYNALVEKAN---RTDLAESESTKYQTQLRDLESNLKRIT--HEHQTLIVQ 920
            +  ++D  +  +A + +AN   R  + + E+ + Q   R++E   ++I    E +T I  
Sbjct: 1513 KRQMNDEVREKDA-INRANEELRQKVKKVETDRIQLN-RNVEERTQKIAVLEESKTAI-- 1568

Query: 921  KKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEE 980
             +KE  DL        +S +  ++ L E   + ++ +   +A+L +  ++++N     +E
Sbjct: 1569 -QKEAGDLRASLREVEKSRLEARRELQE-LRRQVKTLDTDKAKLTKDIHDLQNRVARDDE 1626

Query: 981  LNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKD-----EEIIALNQKINNA 1035
              + N + I    QK   +      +   ++ +    LK+KD     +E  +  ++I+  
Sbjct: 1627 KEEENRKEIYALKQKSARKDAQNLTRRFGDLEE-ELRLKEKDYAMSVDEARSAERRISER 1685

Query: 1036 QVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQ 1082
              +  + + + ++ L     KL   E  +  +  QL   +   +E++
Sbjct: 1686 LRTTENALDETKADLGDLKLKLSAAEGRVNGLESQLAQVEGAKQEVE 1732



 Score = 66.1 bits (154), Expect = 8e-09
 Identities = 84/395 (21%), Positives = 175/395 (44%), Gaps = 46/395 (11%)

Query: 487  QELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDN 546
            +E   ++    ++ L+ +++  E + T L   +D  + ++ + +        Q+Q     
Sbjct: 1982 KETESQVLQDRIEALMRQIQDLESKNTSLQLTVDRLSSSLARSEEGEHTLKDQLQSLS-- 2039

Query: 547  FSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEME 606
               ++D+  E  +  E+LHHL Q VA  E+++  LQ  L   D+ R   SD  K+  ++ 
Sbjct: 2040 -LSLNDTAMESTQKQEQLHHLQQAVANSEKDRRVLQERL---DAARHGASDAKKQNHQLI 2095

Query: 607  NLAETRLKAISLLESQKFDLVQEL----HILQQKYDEVEDKLADISQLQSDQVCSEIKSV 662
               +     ++  E ++ +L Q++     +++Q  +  E  +  I + Q+++   +    
Sbjct: 2096 ERVQQGQNDLAECELRRAELEQQVRSSQQLVKQHQESEETTMTQIQRFQAEKRSLKEHVT 2155

Query: 663  HLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDK----EDIM----------N 708
             L++    L   K+E+      L+ DK  L  T+  +E +K    E +M           
Sbjct: 2156 TLQKAYSNLETEKREVQRSAGRLEKDKTALKKTLDKVEREKMRHEEAVMRATSEKGALDQ 2215

Query: 709  KLQNYIQENMDL---TDKL-------EKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQ 758
             L +  QEN++L   T  L       E+  A+++ EL  +  H ++++I+T+    A++Q
Sbjct: 2216 SLTSLDQENIELQRQTQALQATLAETEQQHAQRLIELTTR--HRQETEIETERLRTAQLQ 2273

Query: 759  ERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTI 818
                    +E+    ++ R+  LEE  + ++D+ +   RK  Q   Y+    K   E   
Sbjct: 2274 AE----RTLEARERAHRQRVKGLEEQNSTLKDQMHHEVRKRQQ---YISMSSKTNDEIQD 2326

Query: 819  QEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQK 853
              + L + L  +   D  ++  LL  EHE ++L +
Sbjct: 2327 LRNMLSDSLHSVA-RDPTLDPLLL--EHETRKLDE 2358



 Score = 62.5 bits (145), Expect = 9e-08
 Identities = 86/454 (18%), Positives = 192/454 (42%), Gaps = 20/454 (4%)

Query: 649  QLQSDQVC-SEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIM 707
            +LQ D +  SE     ++E+I+ L  S +       N      ++    + +E DK  + 
Sbjct: 1889 KLQDDIIRRSERDRKGMQEKINTLERSLQSAEAEKRNQSDRIAKMNQGSQRMEGDKRSLR 1948

Query: 708  NKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENI 767
              L+        L  K   +  +     L+  + E +S++  Q  I+A +++    I+++
Sbjct: 1949 ETLEASENRCTQLELKRRALEGDLQRSHLSMNDKETESQV-LQDRIEALMRQ----IQDL 2003

Query: 768  ESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRL 827
            ES+ +  +  + RL  S+A  E+  ++L+ +   L   L +     ++   Q   L   +
Sbjct: 2004 ESKNTSLQLTVDRLSSSLARSEEGEHTLKDQLQSLSLSLNDTAMESTQKQEQLHHLQQAV 2063

Query: 828  AVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTD 887
            A      RV++++L    H   + +K+N  L+E  Q  Q  L++ +     L ++   + 
Sbjct: 2064 ANSEKDRRVLQERLDAARHGASDAKKQNHQLIERVQQGQNDLAECELRRAELEQQVRSSQ 2123

Query: 888  L-----AESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRD 942
                   ESE T   TQ++  ++  KR   EH T + +    +E  + E         +D
Sbjct: 2124 QLVKQHQESEETT-MTQIQRFQAE-KRSLKEHVTTLQKAYSNLETEKREVQRSAGRLEKD 2181

Query: 943  KKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPD 1002
            K  L +  +K      + E  +    +    L+ ++  L++ N+EL  +  Q  Q    +
Sbjct: 2182 KTALKKTLDKVEREKMRHEEAVMRATSEKGALDQSLTSLDQENIEL-QRQTQALQATLAE 2240

Query: 1003 YTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEE 1062
              +Q+   + +L    +Q+ E      +++  AQ   +      E++      +++ +EE
Sbjct: 2241 TEQQHAQRLIELTTRHRQETE---IETERLRTAQ---LQAERTLEARERAHRQRVKGLEE 2294

Query: 1063 EMQRVSKQLLDSKQHNEELQILVREQDDQIKELK 1096
            +   +  Q+    +  ++   +  + +D+I++L+
Sbjct: 2295 QNSTLKDQMHHEVRKRQQYISMSSKTNDEIQDLR 2328



 Score = 56.8 bits (131), Expect = 5e-06
 Identities = 92/522 (17%), Positives = 222/522 (42%), Gaps = 49/522 (9%)

Query: 483  EQLKQELNDEIKDVNVKDLIEKLKSAEEQ-----ITQLNDEIDAANKNMIKVKSNHKLK- 536
            EQL  +++ E   + +KD  ++LK  E +     +T+  +    A+ ++    +  KL+ 
Sbjct: 1833 EQLVADIDPETVRIALKDFSQQLKDTERERFQKSLTEAYEGKSGADGHLNNEHTALKLQD 1892

Query: 537  ---------LKQMQKTIDNFSK-VSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLV 586
                      K MQ+ I+   + +  +  E    ++ +  ++Q    +E +K +L+   +
Sbjct: 1893 DIIRRSERDRKGMQEKINTLERSLQSAEAEKRNQSDRIAKMNQGSQRMEGDKRSLR-ETL 1951

Query: 587  DYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLAD 646
            +    R  + ++ ++ +E  +L  + L +++  E++   L   +  L ++  ++E K   
Sbjct: 1952 EASENRCTQLELKRRALE-GDLQRSHL-SMNDKETESQVLQDRIEALMRQIQDLESKNTS 2009

Query: 647  ----ISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLEND 702
                + +L S    SE     L++Q+ +LS S  + A+     +     L   + + E D
Sbjct: 2010 LQLTVDRLSSSLARSEEGEHTLKDQLQSLSLSLNDTAMESTQKQEQLHHLQQAVANSEKD 2069

Query: 703  KEDIMNKL-------QNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDA 755
            +  +  +L        +  ++N  L +++++   +     L +   E+Q +   Q     
Sbjct: 2070 RRVLQERLDAARHGASDAKKQNHQLIERVQQGQNDLAECELRRAELEQQVRSSQQLVKQH 2129

Query: 756  KIQERD--LYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAY 813
            +  E      I+  ++E    K  +  L+++ + +E  +  ++R A +L       +K  
Sbjct: 2130 QESEETTMTQIQRFQAEKRSLKEHVTTLQKAYSNLETEKREVQRSAGRLEKDKTALKKTL 2189

Query: 814  SEYTIQEDELVNRLAVL--MDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSD 871
             +  ++ +++ +  AV+        +++ L  ++ EN ELQ+       + Q LQ +L++
Sbjct: 2190 DK--VEREKMRHEEAVMRATSEKGALDQSLTSLDQENIELQR-------QTQALQATLAE 2240

Query: 872  M-QQHYNALVEKANRTDLAESESTKYQTQ-LRDLESNLKRITHEHQTLIVQKKKEIEDLE 929
              QQH   L+E   R      + T+ +T+ LR  +   +R     +    Q+ K +E+  
Sbjct: 2241 TEQQHAQRLIELTTR----HRQETEIETERLRTAQLQAERTLEARERAHRQRVKGLEEQN 2296

Query: 930  IEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNI 971
                 Q+   +R ++       K  + +  L   L +  +++
Sbjct: 2297 STLKDQMHHEVRKRQQYISMSSKTNDEIQDLRNMLSDSLHSV 2338



 Score = 37.9 bits (84), Expect = 2.3
 Identities = 58/301 (19%), Positives = 120/301 (39%), Gaps = 28/301 (9%)

Query: 827  LAVLMDHDRVVEKQLLEIEH-------ENKELQKKNQIL---LEENQNLQISLSDMQQHY 876
            L  L + +R+++ +L  +E        +  EL  K Q L   LE++          ++  
Sbjct: 71   LGNLQEENRMLQNELSRVEDLLSSSRADRDELAIKYQALSDRLEQSYKADAGFEREREEQ 130

Query: 877  NALVEKAN---RTDLAESESTKYQTQLRDLESNLKR---ITHEHQTLIVQKKKEIEDLEI 930
            N  +   N   R  L E E   Y+ +L+  +   +R   +  + Q  ++Q K++  DLE 
Sbjct: 131  NRSLVSQNVELRRKL-EDEHGSYKRKLQAYQDGQQRQAQLVQKLQAKVLQYKRKCGDLES 189

Query: 931  EFNTQIESAIRDK---KVLNEKYEK-----NIEYVTQLEAQLQEYKNNI-ENLNMNVEEL 981
                 +  + R+K   +V     E       +E   Q  A L +  + + E L+   E  
Sbjct: 190  SLQDSLNESDREKISMRVDEHATELEGTLIRLEEEQQRSASLAQVNSMLREQLDQATEAN 249

Query: 982  NKMNLEL--IDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSY 1039
              +N E+  +   V++ Q    +   ++ +E    N     +   ++ L ++I   + ++
Sbjct: 250  RSLNHEIDQLSNEVKRSQDDLDNRETEWRDEEKSFNEYFNSEHSRLLVLWRQIVAFRRNF 309

Query: 1040 MSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETK 1099
              M S  E  L Q  + +       Q   + L  + Q +E   ++  E++   K   E++
Sbjct: 310  AEMKSSTERDLTQMRSDVTRTSRNTQSACQNLQSASQGSETGAVMALEREKGEKMQLESQ 369

Query: 1100 L 1100
            +
Sbjct: 370  M 370



 Score = 37.5 bits (83), Expect = 3.0
 Identities = 93/538 (17%), Positives = 202/538 (37%), Gaps = 36/538 (6%)

Query: 1050 LAQFTTKLENMEEE-MQRVSKQLLDSKQ----HNEELQILVREQDDQIKELKETKLTFEM 1104
            L  F+ +L++ E E  Q+   +  + K     H       ++ QDD I+  +  +   + 
Sbjct: 1848 LKDFSQQLKDTERERFQKSLTEAYEGKSGADGHLNNEHTALKLQDDIIRRSERDRKGMQE 1907

Query: 1105 NIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSV-LQEQSAK 1163
             I   E  + S+  E  +                     ++E  E  + R   L+ +   
Sbjct: 1908 KINTLERSLQSAEAEKRNQSDRIAKMNQGSQRMEGDKRSLRETLEASENRCTQLELKRRA 1967

Query: 1164 LNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSS 1223
            L  +LQ  +  +   ET +  L       Q++I  L  +++ L ++N +L  TV  L SS
Sbjct: 1968 LEGDLQRSHLSMNDKETESQVL-------QDRIEALMRQIQDLESKNTSLQLTVDRLSSS 2020

Query: 1224 ISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEET 1283
            ++ + +       +L    L+  +   + T+            K EQL    Q+    E 
Sbjct: 2021 LARSEEGEHTLKDQLQSLSLSLNDTAMESTQ------------KQEQLHHLQQAVANSEK 2068

Query: 1284 NKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQI---EILRSEIEDEKVAFXXXXXX 1340
            ++ V  E++ + ++   D ++    L E+     N +   E+ R+E+E +  +       
Sbjct: 2069 DRRVLQERLDAARHGASDAKKQNHQLIERVQQGQNDLAECELRRAELEQQVRSSQQLVKQ 2128

Query: 1341 XXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEA 1400
                       ++   Q+ K+  ++ +  + +  + L+ +             +   A  
Sbjct: 2129 HQESEETTMTQIQ-RFQAEKRSLKEHVTTLQKAYSNLE-TEKREVQRSAGRLEKDKTALK 2186

Query: 1401 KVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELA 1460
            K L+   + +++  E   +       L Q     +    +L    + ++    E E + A
Sbjct: 2187 KTLDKVEREKMRHEEAVMRATSEKGALDQSLTSLDQENIELQRQTQALQATLAETEQQHA 2246

Query: 1461 ILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLN--KQVAELNKALEEEVAK 1518
              RL      +  ET  +   +   +L  E  ++  E       K + E N  L++++  
Sbjct: 2247 -QRLIELTTRHRQETEIETERLRTAQLQAERTLEARERAHRQRVKGLEEQNSTLKDQMH- 2304

Query: 1519 TNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTM 1576
             +E++   +   +   T NDEI +L+NM+  S   + +  +      +    +LD +M
Sbjct: 2305 -HEVRKRQQYISMSSKT-NDEIQDLRNMLSDSLHSVARDPTLDPLLLEHETRKLDESM 2360


>UniRef50_Q23QE6 Cluster: Guanylate-binding protein, N-terminal domain
            containing protein; n=1; Tetrahymena thermophila
            SB210|Rep: Guanylate-binding protein, N-terminal domain
            containing protein - Tetrahymena thermophila SB210
          Length = 1697

 Score =  136 bits (329), Expect = 5e-30
 Identities = 246/1179 (20%), Positives = 491/1179 (41%), Gaps = 111/1179 (9%)

Query: 475  VNEIAKVQEQLKQELNDEIKDVNVKDLIEKL---KSAEEQITQLND-EIDAANKNMIKVK 530
            VN      E L++ +N E  ++ VK+L +++   +S   ++ + N+ E+    K     +
Sbjct: 480  VNRNVIFLEFLQRSIN-EAANIFVKNLEQEVDIQRSCNSEVQRRNETELVELRKKTDNER 538

Query: 531  SNHKLKLKQMQKTIDNFSKVSDSNKEIVR-LTEELHHLSQKVAEL-EEEKGNLQLHLVDY 588
               + K++Q+ K  D+ +     N+  V+ + EE   + ++  EL   E+  L   + + 
Sbjct: 539  VLLERKVEQLLKEKDSIATDKVKNERAVKEIEEEKQKMEKEYKELLNSERVELNDQINNL 598

Query: 589  DSGRMIESDVYKKMIEMENLAETRL-KAISLLE--SQKFDLVQELHILQQKYDE--VEDK 643
             +   I  +  KK+     L E+   K  +LLE  +Q F+ + E ++ + K  E  ++  
Sbjct: 599  RNKSKITEETLKKVERELLLKESSFQKEKALLEQRAQHFEKLCEEYLAKDKATENMMQST 658

Query: 644  LADIS-QLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLEND 702
             +  + Q++  Q   E     LE ++  L  S  EL   I N   +  Q   T++  E  
Sbjct: 659  HSGFNTQMKEQQTKYERIIKELENKLTNLKESNFELNEKISNQSQNFSQEVETLQTRERG 718

Query: 703  KEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDL 762
                + +LQ  I        +      + + +L  + N+E           D KIQ   L
Sbjct: 719  LLRQIEELQTEISSTKKQLSEASTNGLKNLGDLKEQFNNETN---------DLKIQNTQL 769

Query: 763  YIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDE 822
              E +   L K+K  +  L +  A+++ +   +  + D+  S L E +KA+ E T+Q  E
Sbjct: 770  Q-EELSKTLDKHKQDVSELRKREALLQQQIEFVRHELDESRSQLVEAKKAH-ESTLQALE 827

Query: 823  LVNRLAVLMDHDRVVEKQLLEIEHEN-KELQKKNQILLEENQNLQIS-------LSDMQQ 874
            + N     M  +   +KQ+LE++  + K+++      L + + LQ         LSD++ 
Sbjct: 828  INN-----MGDEESGQKQILELKDTHMKQIRAMEAEALSQKKTLQSQIDALNKELSDLEL 882

Query: 875  HYNALVE------KANRTDLAESES--TKYQTQLRDLESNLKRITHEHQTLIVQKKKEIE 926
             Y   +       K     L ES++  T+  T+L + E  LK  + + +   +QK +E+E
Sbjct: 883  KYKVSIHDYETEVKTLSDQLTESQAIRTQLSTKLSESEEMLKLSSKDMEKKFIQKIRELE 942

Query: 927  DLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNL 986
            D       + +S IR+ +  +E+              LQ+ KN  E   +  E L K  +
Sbjct: 943  DTNEAIKDRSQSEIRENQAKSEE-------------SLQQLKNMFE---IERETLEKRLI 986

Query: 987  ELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDY 1046
            E  +K  +K   Q     E+Y  ++ +  A L   +EEI  L   I + ++  ++M   Y
Sbjct: 987  EEKEKR-EKSYNQ---VVEEYEQKLREEQAAL---EEEIENLRDDIKDYEIQVINMQGQY 1039

Query: 1047 ESKLAQFTTKLENMEEEMQRVSKQLLDSK-QHNEELQILVREQDDQIKELKETKLTFEMN 1105
            E +L      +EN+E+ +Q    QLL S+  +  +L+  +   +   KEL++   T + N
Sbjct: 1040 EHELDLKQKTIENLEKMLQETKAQLLSSQASYQSQLEQQMASYNADRKELQQKYETVQKN 1099

Query: 1106 IPKTEGMIISSTIEPMSDDA---------------NNVDXXXXXXXXXXXXLKVQEEEEF 1150
            +  ++  I++ T +  S +A               N ++             K QE  + 
Sbjct: 1100 LQLSDNKILTLTQKLESSEASYENKKKELAQLKQDNIIERQALEEKLEETRKKYQELSDE 1159

Query: 1151 IQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTEN 1210
              +  +  E+S  L+++  E Y K +Q   L   L       +E++   K++  Q   E 
Sbjct: 1160 HLQTKINSEKSIALSSQQNEFYQKKVQ--ELQVALESSTQRFEERLKTSKAEWAQETLEK 1217

Query: 1211 -DNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYE 1269
              NL      L S I++       +  + ++    +R  D +K +     +L   ESK +
Sbjct: 1218 IQNLQDEKVNLESKINALK-----KSTKEFETQYQKRVTDLEKEKAIYVEKLQYTESKLK 1272

Query: 1270 QLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIED 1329
            +  D     T++  +++   ++ TS + K+  +E  +  L+ +   + N+   L +  E 
Sbjct: 1273 ETEDKYMIETEQLKDQLSKAKEFTSTEKKMLIQE--IEKLKSQNVQLDNEKHELNTSYER 1330

Query: 1330 EKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXX 1389
            +KV +                DL    + +    EQ++ ++ ++    K           
Sbjct: 1331 DKVLWEGKFSFLQQQKEQAKQDLIEAQKKF----EQTLTHLQKQRQNEKNEREQSVSDML 1386

Query: 1390 XXXXRVNDAEAKVLELTHQLELK--DSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKR 1447
                R    +   L+ T   +L   + +I +   E   +L Q   E        +  EKR
Sbjct: 1387 MQIERKYQTQISELQETSNTKLSAANQKITKLEAELKNSLDQTMMESRQKNSNAIFTEKR 1446

Query: 1448 IEDLTYEKE---SELAILRLKMH-ENANHYETMQKESEIERVKLIEELNVKITESVSLNK 1503
            + +L   ++   SEL I+R +   E       + +E E  + K++ ++  K  E+    K
Sbjct: 1447 LAELLESEKKLSSELDIIRKEREAEKTEAQRKLDQERETLKTKML-QIEEKFREA---EK 1502

Query: 1504 QVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASD 1563
            +   L    E+E AK N  +  L NQ+ E+    ++I   + ++   + +++     +  
Sbjct: 1503 KRNTLIFEHEKERAKWNLEKDHLLNQKNELQENLNKIEKKKEILLRENERLKNDSRQSRR 1562

Query: 1564 TKQGRDEQLDN---TMNKELLDAVPRAELDLAMYMLHQR 1599
              +   +Q  N   T N+++++A   + L+++  M  +R
Sbjct: 1563 QFERLSDQNSNIFLTQNRQMMNANQPSFLNMSRNMGSER 1601


>UniRef50_UPI00006615CF Cluster: Homolog of Homo sapiens "Golgi
            autoantigen, golgin subfamily B member 1; n=1; Takifugu
            rubripes|Rep: Homolog of Homo sapiens "Golgi autoantigen,
            golgin subfamily B member 1 - Takifugu rubripes
          Length = 4286

 Score =  136 bits (328), Expect = 6e-30
 Identities = 245/1237 (19%), Positives = 519/1237 (41%), Gaps = 111/1237 (8%)

Query: 360  SSPSKKGSPL-ISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLN 418
            S+P  + +P  +   S +N   K++S   QL+S    Q  D + ++  +  L   +Q L+
Sbjct: 609  STPDTESNPCTLVCFSAQNELEKLQS---QLASVRHQQSRDAEKHQLLVTSLNEQLQGLS 665

Query: 419  KDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHME-GPSLIHVGTNTEDVNE 477
                  E  + EK+              +L   L L+  Q  E    L+    + E++++
Sbjct: 666  DMQESLESSLVEKENTLAKTSEKLELVSSLRESLSLKETQFKEVSDKLLQTEQSLENISQ 725

Query: 478  IAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQIT--QLNDEIDAANKNMIKVKSNHKL 535
                 E+   EL  E+ D+  K  + K K+ ++++T   L  E+D  N+ + K+ + +  
Sbjct: 726  KCSGSEKQCGELKSEVTDLTQKLSLLKEKTQKQEVTIDTLQTEVDQTNEELDKLNTAYLE 785

Query: 536  KLKQMQKTIDNFSKVSDSNKEIV-RLTEELHHLSQKVAELEEEKGNLQLHL-VDYDSGRM 593
            +  Q+   + +  +  DS K+++    +E+  LS  ++E  E+   L+  L +  D+   
Sbjct: 786  ERAQLIHDLQSCEREIDSLKDVLLEKDKEISVLSGNISEYTEQLIALKQDLKMKEDNLIQ 845

Query: 594  IESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVED----KLADISQ 649
            +E+ + K   E+  L E++      LE++  +L++ L   + +  +  D    K A++  
Sbjct: 846  VENALSKAEREVSILRESQNSDQRTLENKITELMENLKDTEMELLKARDLRDSKTAEVET 905

Query: 650  L--QSDQVCSEIKSVH--LEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKE- 704
            L  Q+D     I+ +   +++Q+ +      E  + I +LK   EQL  + + L+   E 
Sbjct: 906  LVKQADDDKKAIQELRGEIQKQLQSHCHHLSECEMHIASLK---EQLMSSAQKLQEALEL 962

Query: 705  --DIMNKLQNYIQENMDLTDKLEKMSA--EKISELLAKINHEEQSKIQTQFGIDAKIQER 760
                 NK Q++ +E     D+  ++ +  EK    +  ++ + + + +T+  I  +++E+
Sbjct: 963  QQQFSNKEQSFEKELKSSKDEQNRLCSQVEKYRNEMHVVSQQLEEQTRTEDIIRGEMKEK 1022

Query: 761  DLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQE 820
            +  I ++E +L +  +++   EE     ED   + + + +++ S LQ K +  S      
Sbjct: 1023 EQIIASLEIQLKEAGAQV---EEERQRFEDALKTRDSEREKMSSDLQSKSENISNLQNLL 1079

Query: 821  DELVNRLAVLMDHDRVVEKQLLEIEHEN-KELQKKNQILLEENQNLQISLSDMQQHYNAL 879
            + L N    L ++   +  +  E++ +N  +L+++    L+ N + Q  +  +      L
Sbjct: 1080 NSLKNEKKQLQENLEALTGEF-EMQKQNVHQLKEQVTSALDSNASYQNQVQQLSAEAARL 1138

Query: 880  VEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESA 939
             ++ + + +  SE    +  LRD  S L+R   ++ T+I   +K+ E+L ++ N+++   
Sbjct: 1139 QQELSDSQITISELRCEKESLRDEVSVLERQVSQNSTVIEALQKDKEELTLQ-NSELSRG 1197

Query: 940  IRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQ 999
                     + +     V QL++ +      + NL M +E   K  ++L     Q++++ 
Sbjct: 1198 ---------RVQSLTSKVDQLQSDVAGKDGTLGNLQMTMEAQQKRLMQL-----QEEESS 1243

Query: 1000 SPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLEN 1059
                  +   E+ K N  LK +     A N KI     S  +       + +Q   +++N
Sbjct: 1244 LKSQLREK-EEVWKENQCLKSE-----ASNHKI--TVCSLQAEAESLREQHSQVCQQIKN 1295

Query: 1060 MEEEMQRVSKQLLDSKQHNEELQI---LVREQDDQIKELKETKLTFEMNIPKTEGMII-- 1114
             EE ++ V  Q    ++H EEL +    ++   +QI  L+      E +     G ++  
Sbjct: 1296 GEETLRNVKHQ---CQKHKEELNVTNETIKSLTEQIGVLEGNARELESDAELRRGEVVKL 1352

Query: 1115 SSTIEPMSDDANNV-------DXXXXXXXXXXXXLKVQEEEEFIQERS------VLQEQS 1161
             S I+  +++ + +       +            L  Q E+   Q  S      +L E +
Sbjct: 1353 QSHIQAATEENHQLRAACESKEKELAHHSQVLLDLNGQLEKALEQNSSFSATVNILTENN 1412

Query: 1162 AKLNTELQECYTKIIQL----ETLNTELTGHD---VVNQEQINQLKSKLEQLNTENDNLL 1214
             +L  EL +    + +L     +L   L+G +     +++ I++L  + E+L T  D   
Sbjct: 1413 QRLQEELAQKEKAVSELNADKSSLQELLSGLEKQISEDRQAIDRLLKEKEELATAADGFK 1472

Query: 1215 STVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDS 1274
              + E   S S+ + Q+  E   L K  L ++E   Q    E        +   +Q+ + 
Sbjct: 1473 KVLQESEQSNSAGLLQKTNECEALSKV-LKEKEGWLQNLREEA-------DGLKKQVAEL 1524

Query: 1275 VQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADV---INQIEILRSEIEDEK 1331
             +  TQ+E   +    Q+   QN+L    + +R LQE+ + +   I + + L  +  +E+
Sbjct: 1525 TEMFTQKEQTALAQRSQLEDKQNELLQLHDAIRVLQEQESVLRSGIMEKDALIQQGAEER 1584

Query: 1332 VAFXXXXXXXXXXXXXXXXDLRT------ENQSYKQMQEQSILNINEENAQLKKSSXXXX 1385
              +                +L T      E Q   Q +E+      +E  +  +S     
Sbjct: 1585 QVYQREISREKSVVSQLQAELETVRGDCAEAQLQLQQREEEFQMSRDELNKQTQSVVLLS 1644

Query: 1386 XXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYE 1445
                    R  + E +V +L  +  L   E+ Q+  E     T   D+ + +++Q   ++
Sbjct: 1645 SQLGEANERAREMEVRVQKLADEHRLLTRELEQRNAE----ATDLTDDAQALKEQSAAFK 1700

Query: 1446 KRIE-DLTYEKESELAILRLKMH-ENANHYETMQKESEIERVKLIEELNVKITESVSLNK 1503
              ++  +T    S+  + RLK         + + +E +       E L  K T    LN 
Sbjct: 1701 SELQKTVTALARSQEEVTRLKTECSGLERLQGILQEKD-------EALRQKDTLVQQLND 1753

Query: 1504 QVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEI 1540
             +AEL+K L+++          + + E  +  L D++
Sbjct: 1754 SMAELDKMLKQKTDDAVGQSAKISDLEDSVCRLRDQV 1790



 Score =  130 bits (315), Expect = 2e-28
 Identities = 241/1221 (19%), Positives = 488/1221 (39%), Gaps = 115/1221 (9%)

Query: 391  SETLNQDTDKKINKNEI-AKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLI 449
            S+   Q+  K   K++  A LE ++++L + L +KE V+  K            G+D  I
Sbjct: 280  SQMHEQELFKLAAKSDASADLEQLLKALKQKLHEKEEVLLGKTQVINVLQGEVDGRDQQI 339

Query: 450  AQLQLEHQQHMEGPSLIHVGTNTEDVN----EIAKVQEQLK---QELNDEIKDVNVKDLI 502
                 EH+     P +      TED +    +  K++   K   ++L +E+K +   D  
Sbjct: 340  KVSITEHKCRF--PRVAQAKQKTEDASRSEAKFLKMKAWSKSRIRQLEEELKKIQAGDAH 397

Query: 503  EKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLK------------QMQKTIDNFSKV 550
              L S + +IT L +E +   +N+ K++   +L+ K            + Q+T+   + +
Sbjct: 398  LDLISLQSRITALEEERE---ENLCKLEQYDELQAKNEMLQAKLAAYEEQQRTLQ--ADL 452

Query: 551  SDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDV--YKKMIEMENL 608
                K        L   S K +    +  N  +   +  S    +S V  +++M+     
Sbjct: 453  EQFTKRAASQVRALGFQSTKTSRTHCKCMNGLILASESGSADDAQSQVLEWQEMVAEAAT 512

Query: 609  AETRLKAISLLESQKFD-LVQELHILQQKYDEVEDKLADISQLQSDQV----CSEIKSVH 663
            A  R K      + +   + +E   L+ +  E+E++LA    L   +         +S+ 
Sbjct: 513  ARERAKEEKAAMALRISHMEEEREALETRQQELEEELAQARGLGQHRAKKPAAPSQRSLQ 572

Query: 664  LEEQIDALSASKKELALVIENLKLDKEQLYG-----TIKDLENDKEDIM-----NKLQNY 713
             + + D  S  +   +       ++ E + G     +  D E++   ++     N+L+  
Sbjct: 573  EDFEFDGQSQFQDPRSTSESTTPMEGENMGGWWPEHSTPDTESNPCTLVCFSAQNELEK- 631

Query: 714  IQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESEL-- 771
            +Q  +      +   AEK   L+  +N + Q     Q  +++ + E++  +     +L  
Sbjct: 632  LQSQLASVRHQQSRDAEKHQLLVTSLNEQLQGLSDMQESLESSLVEKENTLAKTSEKLEL 691

Query: 772  -SKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVL 830
             S  +  +   E     + D+    E+  + +       +K   E   +  +L  +L++L
Sbjct: 692  VSSLRESLSLKETQFKEVSDKLLQTEQSLENISQKCSGSEKQCGELKSEVTDLTQKLSLL 751

Query: 831  MDHDRVVEKQL----LEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNAL----VEK 882
             +  +  E  +     E++  N+EL K N   LEE   L   L   ++  ++L    +EK
Sbjct: 752  KEKTQKQEVTIDTLQTEVDQTNEELDKLNTAYLEERAQLIHDLQSCEREIDSLKDVLLEK 811

Query: 883  ANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRD 942
                 +     ++Y  QL  L+ +LK      +  ++Q +  +   E E +   ES   D
Sbjct: 812  DKEISVLSGNISEYTEQLIALKQDLKM----KEDNLIQVENALSKAEREVSILRESQNSD 867

Query: 943  KKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEEL------NKMNLELIDKHVQKQ 996
            ++ L  K  + +E +   E +L + ++  ++    VE L      +K  ++ +   +QKQ
Sbjct: 868  QRTLENKITELMENLKDTEMELLKARDLRDSKTAEVETLVKQADDDKKAIQELRGEIQKQ 927

Query: 997  QTQSPDYTEQYINEINKLNALLK---QKDEEIIALNQKINNAQVSYMSMVSDYESKLAQF 1053
                  +  +    I  L   L    QK +E + L Q+ +N + S+   +   + +  + 
Sbjct: 928  LQSHCHHLSECEMHIASLKEQLMSSAQKLQEALELQQQFSNKEQSFEKELKSSKDEQNRL 987

Query: 1054 TTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIK----ELKETKLTFEMNIPKT 1109
             +++E    EM  VS+QL +  +  + ++  ++E++  I     +LKE     E    + 
Sbjct: 988  CSQVEKYRNEMHVVSQQLEEQTRTEDIIRGEMKEKEQIIASLEIQLKEAGAQVEEERQRF 1047

Query: 1110 EGMIIS--STIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTE 1167
            E  + +  S  E MS D  +              LK         E+  LQE    L  E
Sbjct: 1048 EDALKTRDSEREKMSSDLQSKSENISNLQNLLNSLK--------NEKKQLQENLEALTGE 1099

Query: 1168 LQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSA 1227
             +     + QL+   T     +   Q Q+ QL ++  +L  E  +   T++ELR    S 
Sbjct: 1100 FEMQKQNVHQLKEQVTSALDSNASYQNQVQQLSAEAARLQQELSDSQITISELRCEKESL 1159

Query: 1228 VDQRGFEIAELWKQHLAQREADFQKTEHELRVQLS--------AFESKYEQLLDSVQSST 1279
             D+      ++  Q+    EA  QK + EL +Q S        +  SK +QL   V    
Sbjct: 1160 RDEVSVLERQV-SQNSTVIEA-LQKDKEELTLQNSELSRGRVQSLTSKVDQLQSDVAGKD 1217

Query: 1280 QEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXX 1339
                N  +TME       +LQ++E  L++   +  +V  + + L+SE  + K+       
Sbjct: 1218 GTLGNLQMTMEAQQKRLMQLQEEESSLKSQLREKEEVWKENQCLKSEASNHKITVCSLQA 1277

Query: 1340 XXXXXXXXXXXDLRTENQSYKQMQ--EQSILNINEENAQLKKSSXXXXXXXXXXXXRVND 1397
                            +Q  +Q++  E+++ N+  +  + K+              ++  
Sbjct: 1278 EAESLR-------EQHSQVCQQIKNGEETLRNVKHQCQKHKEELNVTNETIKSLTEQIGV 1330

Query: 1398 AEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEF----ENVRQQLVEYEKRIEDLTY 1453
             E    EL    EL+  E+  K   +    T+ N +     E+  ++L  + + + DL  
Sbjct: 1331 LEGNARELESDAELRRGEVV-KLQSHIQAATEENHQLRAACESKEKELAHHSQVLLDLNG 1389

Query: 1454 EKESEL---AILRLKMHENANHYETMQKESEIERVKLIEELNV---KITESVS-LNKQVA 1506
            + E  L   +     ++    + + +Q+E   ++ K + ELN     + E +S L KQ++
Sbjct: 1390 QLEKALEQNSSFSATVNILTENNQRLQEEL-AQKEKAVSELNADKSSLQELLSGLEKQIS 1448

Query: 1507 ELNKALEEEVAKTNEMQTALE 1527
            E  +A++  + +  E+ TA +
Sbjct: 1449 EDRQAIDRLLKEKEELATAAD 1469



 Score =  124 bits (298), Expect = 3e-26
 Identities = 271/1456 (18%), Positives = 597/1456 (41%), Gaps = 113/1456 (7%)

Query: 143  DVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEK-DQIIEAKNKATTXXXXXXX 201
            ++  L + + EKD  +SVL   +      ++ L++ +  K D +I+ +N A +       
Sbjct: 800  EIDSLKDVLLEKDKEISVLSGNISEYTEQLIALKQDLKMKEDNLIQVEN-ALSKAEREVS 858

Query: 202  XXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLE 261
                         + ++T++ EN        KD +  LLK  + +D + + +E   K  +
Sbjct: 859  ILRESQNSDQRTLENKITELMENL-------KDTEMELLKARDLRDSKTAEVETLVKQAD 911

Query: 262  AARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQ--SIEPSCEEKTEIEEK-GSLEI 318
              +  I     ++ ++L+               L +Q  S     +E  E++++  + E 
Sbjct: 912  DDKKAIQELRGEIQKQLQSHCHHLSECEMHIASLKEQLMSSAQKLQEALELQQQFSNKEQ 971

Query: 319  ANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNT 378
            +   EL    +    L  Q+ +   E+   + +   E +  +    +G      +   + 
Sbjct: 972  SFEKELKSSKDEQNRLCSQVEKYRNEMH--VVSQQLEEQTRTEDIIRGEMKEKEQIIASL 1029

Query: 379  ASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVI-SEKDTXXXX 437
              ++K   +Q+  E    +   K   +E  K+   +QS ++++ + + ++ S K+     
Sbjct: 1030 EIQLKEAGAQVEEERQRFEDALKTRDSEREKMSSDLQSKSENISNLQNLLNSLKNEKKQL 1089

Query: 438  XXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTED-VNEIAKVQEQLKQELNDEIKDV 496
                         Q Q  HQ   +  S +    + ++ V +++    +L+QEL+D    +
Sbjct: 1090 QENLEALTGEFEMQKQNVHQLKEQVTSALDSNASYQNQVQQLSAEAARLQQELSD--SQI 1147

Query: 497  NVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKE 556
             + +L  + +S  ++++ L  ++ + N  +I+     K +L     T+ N S++  S   
Sbjct: 1148 TISELRCEKESLRDEVSVLERQV-SQNSTVIEALQKDKEEL-----TLQN-SEL--SRGR 1198

Query: 557  IVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAI 616
            +  LT ++  L   VA  +   GNLQ+  ++    R+++    +  ++    ++ R K  
Sbjct: 1199 VQSLTSKVDQLQSDVAGKDGTLGNLQM-TMEAQQKRLMQLQEEESSLK----SQLREKEE 1253

Query: 617  SLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVH--LEEQIDALSAS 674
               E+Q        H +     + E   A+  + Q  QVC +IK+    L          
Sbjct: 1254 VWKENQCLKSEASNHKITVCSLQAE---AESLREQHSQVCQQIKNGEETLRNVKHQCQKH 1310

Query: 675  KKELALVIENLKLDKEQ---LYGTIKDLENDKE---DIMNKLQNYIQENMDLTDKLEKMS 728
            K+EL +  E +K   EQ   L G  ++LE+D E     + KLQ++IQ   +   +L    
Sbjct: 1311 KEELNVTNETIKSLTEQIGVLEGNARELESDAELRRGEVVKLQSHIQAATEENHQLRAAC 1370

Query: 729  AEKISELLAKINHEEQSKIQTQFGIDAKIQERDLY--IENIESELS-KYKSRICRLEESI 785
              K  EL     H  Q  +     ++  +++   +    NI +E + + +  + + E+++
Sbjct: 1371 ESKEKELA----HHSQVLLDLNGQLEKALEQNSSFSATVNILTENNQRLQEELAQKEKAV 1426

Query: 786  AVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRL----AVLMDHDRVVEKQL 841
            + +   + SL+     L   + E ++A      +++EL         VL + ++     L
Sbjct: 1427 SELNADKSSLQELLSGLEKQISEDRQAIDRLLKEKEELATAADGFKKVLQESEQSNSAGL 1486

Query: 842  LEIEHENKELQKKNQILLEEN---QNLQISLSDMQQHYNALVEKANRTDLAESESTKYQT 898
            L+  +E + L K   +L E+    QNL+     +++    L E   +    E  +   ++
Sbjct: 1487 LQKTNECEALSK---VLKEKEGWLQNLREEADGLKKQVAELTEMFTQ---KEQTALAQRS 1540

Query: 899  QLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVT 958
            QL D ++ L ++ H+   ++ +++  +    +E +  I+    +++V   +  +    V+
Sbjct: 1541 QLEDKQNELLQL-HDAIRVLQEQESVLRSGIMEKDALIQQGAEERQVYQREISREKSVVS 1599

Query: 959  QLEAQLQEYKNNI-----------ENLNMNVEELNKMNLELIDKHVQ-KQQTQSPDYTEQ 1006
            QL+A+L+  + +            E   M+ +ELNK    ++    Q  +  +     E 
Sbjct: 1600 QLQAELETVRGDCAEAQLQLQQREEEFQMSRDELNKQTQSVVLLSSQLGEANERAREMEV 1659

Query: 1007 YINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQR 1066
             + ++   + LL ++ E+  A    + +   +     + ++S+L +  T L   +EE+ R
Sbjct: 1660 RVQKLADEHRLLTRELEQRNAEATDLTDDAQALKEQSAAFKSELQKTVTALARSQEEVTR 1719

Query: 1067 VSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDAN 1126
            +  +        E LQ +++E+D+ +++ K+T L  ++N    E   +   ++  +DDA 
Sbjct: 1720 LKTEC----SGLERLQGILQEKDEALRQ-KDT-LVQQLNDSMAE---LDKMLKQKTDDAV 1770

Query: 1127 NVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQ---EQSAKLNTELQECYTKIIQLETLNT 1183
                           L+ Q +   + E S LQ   +Q  +L+ E Q      +Q  TL T
Sbjct: 1771 GQSAKISDLEDSVCRLRDQVDSSGL-EVSTLQHSLKQKEELSLEWQSQSAAAVQ--TLGT 1827

Query: 1184 ELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHL 1243
             L   +V    + + LK K+  L    + L +T+    S +       G +   L  Q  
Sbjct: 1828 NLQAKEV----ECSSLKEKVFHLEESVEKLNNTLQAQTSEVEDLKRVLGQKDVALSDQFK 1883

Query: 1244 AQREADFQKTEHEL-RVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDK 1302
              ++   +  E  L + Q +       QL   + S + +  +   + E+  S  N L  +
Sbjct: 1884 CLQDVQRRADEALLFKTQFTESAELVSQLQSQLHSLSTDSEHLKKSAEETQSAFNNL--R 1941

Query: 1303 EEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSY-KQ 1361
            E++  NL+E   D   Q+     E+   +                    LR+E  +  ++
Sbjct: 1942 EKYAANLEE-LQDARRQLSQRMDEVSGLQ-KLLDDSARQRERASSTTETLRSELSAVCQK 1999

Query: 1362 MQEQSILN--INEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLE----LTHQLELKDSE 1415
            ++E   LN  +++E  +   S             ++     +V      LT  LE ++  
Sbjct: 2000 LEEAEDLNAKLSKEKDEALVSHQANVSLLTVEIEKLKSQYLQVATQLNVLTENLEQREMA 2059

Query: 1416 IYQKTHEYTITLTQRNDEFENVRQQLVEYEKRI-EDLTYEKESELAILRLKMHENANHYE 1474
            ++    +Y++   +   +  +  Q+L E  +R+ E++   KE    +L     ENA+  E
Sbjct: 2060 LHAINSQYSLQ-NKNTSQLVSEMQKLEEVNQRLKEEIALSKEENRKLLTAVSCENAHLKE 2118

Query: 1475 TMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIV 1534
               K S  E+ +L    +      + + ++ + L + +E   ++ + +QT +  Q+ E+ 
Sbjct: 2119 EFSK-SLAEKKELENRCH---QMRLQMEEECSSLKEMMERVTSERDGIQTKVSVQDQELC 2174

Query: 1535 TLNDEITNLQNMVRAS 1550
             L + +  ++ +++ S
Sbjct: 2175 QLKENLQKVEQVLQDS 2190



 Score =  119 bits (286), Expect = 8e-25
 Identities = 296/1591 (18%), Positives = 641/1591 (40%), Gaps = 154/1591 (9%)

Query: 89   GISESLANTLKQKEILMEKIKQY-KELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHL 147
            G +E  A   ++++  M+K++Q  KE+   SST                   +L  VTH 
Sbjct: 2540 GAAEKDAAAEQERKDWMQKLEQLQKEIQNASSTA---------SAAVEEAEKELAQVTHE 2590

Query: 148  SNTIKEKDNA--LSVLQVKMKIMETT---ILDLQEKINEKDQIIEAKNKATTXXXXXXXX 202
               +++K +A  L+  +   K  E       +L E   E   ++E + + T         
Sbjct: 2591 KTKLEKKVHAALLARKETTKKAHEREKKLTQELTELKEEYQALLEQQRQQTNDLNALQFN 2650

Query: 203  XXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIES----KDVRISSLEEANK 258
                     E  K  ++   E  +A   +   E+ + L+D++     ++++  SL     
Sbjct: 2651 FEKKVKEVEELNKTSLSDQDE--LASLKQLMQERDKSLQDLKKTMGEREIQSQSLPNLQM 2708

Query: 259  LLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXL--AKQSIEPS---CEEKTEI--E 311
             LE  + +I   + +LA + E               L  A++ +E +    +EKT+   E
Sbjct: 2709 ELENLKSQIGKMYEELASKDEALTVGEQGAEALKSKLLTAEKHLEEAQAEIKEKTDQAEE 2768

Query: 312  EKGSLEIANMTELTKKIELLEH---LNCQIRQTNKELENKLATMGT--ESKAVSSPSKKG 366
             + +L+   +    +K  L+     L  ++      L++   T     E++   +  ++ 
Sbjct: 2769 RRDALKAFELRVQQEKHVLISEKDALESRLNLLESALQHHTETAAALEETRLQCAEKQRS 2828

Query: 367  SPLISRKSGRNTA--SKMKSPWSQLSSETLNQDTDKK--INKNEIAKLEMVIQSLNKDLV 422
              ++ R+    TA  S++K   S  + +      DK   + K      +    S  +   
Sbjct: 2829 LDVLKREQAEATALISELKDEISSANKKLAEFAKDKTCAVCKTRRDDQDGPCFSCQRH-E 2887

Query: 423  DKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQ 482
            + +  + E++            K+ LIA L+L+ QQ +      H  +      E A++Q
Sbjct: 2888 NLQIKLKEREEAFLMSKAQLSEKEELIAALELQLQQQIGA----HEASMERVKTEAAELQ 2943

Query: 483  E-QLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQ 541
              Q    +ND+     +  L  KL++A     +L  E ++A K  +K +++ K + K+++
Sbjct: 2944 RSQHNGTVNDQDNQSKIAALTRKLQAALLSRKELIKE-NSALKQDVKRQAD-KERAKELE 3001

Query: 542  KTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEE-KGNLQLHLVDYDSGRMIESDVYK 600
                 FS +  + +EI R   EL   +   +  ++  +G +   L D  S   + +    
Sbjct: 3002 -----FSSLEAALEEIKRQNMELESSASSASRDKDRLRGEVDQLLSDNHS---LSAACDS 3053

Query: 601  KMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIK 660
              + +EN+ + +      LES K     EL   + K+ E++ +   + Q   + + SE++
Sbjct: 3054 LKLTIENITQQKEAFSCQLESLKDSQTDELSKWKSKHAELKQEYESLLQ-SYENISSEME 3112

Query: 661  SVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDL 720
               + + ++A    ++E      +L+ +++ L   +  LE ++E I  K++ + +E +  
Sbjct: 3113 K--MRQVLEATKRDQQEAIKKAHHLEAERDVLEKQVAKLEEEQEGIKEKMRKFSKEKLCK 3170

Query: 721  TDKLEKMSAEKISEL--LAKINHEEQSKIQTQFG-IDAKIQERDLYIENIESELSKYKSR 777
             ++LE+ +     EL  L + +  E S++  +   ++A+I +     E ++ +LS+  S 
Sbjct: 3171 VEELEEENRNTRRELTELTENHRTEVSELTDRNRQLEAEICKLKASSEELDEKLSELHSE 3230

Query: 778  ICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSE-------YTIQEDELVNRLAVL 830
                +E  A +E+  Y+LE+ + +  +Y    Q    E        T Q +   + L   
Sbjct: 3231 N---KEMAAKLEEATYTLEKASTESKTYTSSVQLKLDEALGLSNSLTAQMETQTSELGAQ 3287

Query: 831  MDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDM-QQHYNALVEKANRTDLA 889
            M+ +  ++K+   +  + +++Q  +++ L +   +   L D+   H    V    +  + 
Sbjct: 3288 MEVNNSLQKEKQSLCQQLEKMQNDHELQLGKKDVVIQELRDVISGHSQETVSLNEKVRIL 3347

Query: 890  ESESTKYQTQLRDLESNLKRITHEHQ---TLIVQKKKEIEDL----------EIEFNTQI 936
            E + +  Q +L +++    ++ +E++   T+ ++  ++I++L          ++E ++Q+
Sbjct: 3348 EDDKSLLQEELENVQEISDKVKNENEYLETVALRNSEKIDELTESIALLQAQKMELSSQL 3407

Query: 937  ESAIRD--KKVLNEKYEKNIEYVTQLEAQLQEYKNNIE---NLNMNVEELNKMNLELIDK 991
             +A +D   +V  EK E+ +  V + E +L+  +   E   N+N  ++EL K   + I++
Sbjct: 3408 -AATKDMNNQVRQEKEEEQLRLVREFEGKLKTVQRGNEGSKNVNKELQELLKEKHQEINQ 3466

Query: 992  HVQK--------QQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYM--- 1040
              Q          + +S   + Q + E  +L   LK+  EE+ AL QK   A+       
Sbjct: 3467 LQQNCIRYQEVILELESSSKSSQAVAE--ELKRELKKSSEELSALQQKCGRAEAELSVQR 3524

Query: 1041 SMVSDYESKLAQFTTKLENMEEEMQRVSK-------------QLLDSKQHNE-----ELQ 1082
             ++   + KL    ++ + M   + + S+             Q  DS  H E     +++
Sbjct: 3525 DLLLQAKEKLLSVESERDQMASHVSQSSRRPDNQVLQETQPVQKTDSHVHKEFVFQQQIE 3584

Query: 1083 ILVREQDDQIKELKETKLTF-----EMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXX 1137
             L+  +D + K++ E K        EMN  K       + +  +S      +        
Sbjct: 3585 ELILSKDGESKKVDELKRQLDSKDGEMNALKRAMKTNEAKLSALSSSPGGAEASSLWNHL 3644

Query: 1138 XXXXLKVQE----EEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQ 1193
                L  ++    E+ F+ +R  L++   K + E+ +     ++LE    E +      Q
Sbjct: 3645 YQKALNEKDNQLLEQGFVIKR-FLEDMRVK-DKEMNDLRVTHLKLERTINEYSVAAAAQQ 3702

Query: 1194 EQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKT 1253
             Q+  L +   +L+   + + + V +L   +    + +  +  +L     A       K 
Sbjct: 3703 RQLFVLSADNAELSESAELMAAQVKDLSDHVERLEEDKNVQNRQLSDGEDAVSRMQL-KL 3761

Query: 1254 EHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVT-SLQNKLQDKEEHLRNLQE- 1311
            +H  ++   A E++   LL S     Q ++ ++   E +T  L+  LQ K+  + +L   
Sbjct: 3762 QHTEKINADA-EAQL-LLLRSQNDRLQADSERL---EGITVHLKTLLQSKDAEIASLLSC 3816

Query: 1312 KYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNIN 1371
            +   +   I+ L++    +  A+                +LR      + +Q Q   +  
Sbjct: 3817 RDGQMSGYIQQLQANHRSQAAAYEDRLASLGHRREAAVKELRRLEAKLRHLQVQVDRSSQ 3876

Query: 1372 E-ENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLE-------LKDSEIYQKTHEY 1423
            E E   +K  S                ++ + L  T   +       L    + Q+  + 
Sbjct: 3877 EREQTAVKMESFKESMASLQSERERLISQQRTLATTGGKDGAASGERLVSKGMKQEIRKL 3936

Query: 1424 TITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIE 1483
               +   N E   +R QLV Y + +  +   K+++L +L  K  +   + E  +  +E  
Sbjct: 3937 LNQMDDLNSENAMLRAQLVRYREDLNQVLSLKDNQLKVLLQKQQDVIRNLEHQKAAAEKR 3996

Query: 1484 RVKLIEELNVKITESVSLNKQVAELNK--ALEEEVAKTNEMQTALENQEIEIVTLNDEIT 1541
              +   E+  +  ES +L  ++++L    A +E    T   Q +  N+   I  L D + 
Sbjct: 3997 HRETRLEIQRRGEESGALAAEISQLKDRVATQEAEILTLRNQRSATNEGRVIADLQDAVA 4056

Query: 1542 NLQNMVRASSSKIQKHVSFASDTKQGRDEQL 1572
                +  A  S +Q+++        G  EQ+
Sbjct: 4057 ----VKAAECSHLQQNLLSQRTLTDGLQEQI 4083



 Score =  113 bits (271), Expect = 5e-23
 Identities = 267/1432 (18%), Positives = 600/1432 (41%), Gaps = 114/1432 (7%)

Query: 216  QQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLA 275
            Q ++ MQE+   +E+   +++  L K  E  ++ +SSL E+  L E    E+S +  +  
Sbjct: 662  QGLSDMQES---LESSLVEKENTLAKTSEKLEL-VSSLRESLSLKETQFKEVSDKLLQTE 717

Query: 276  QELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIEL-LEHL 334
            Q LE                 KQ  E    E T++ +K SL    + E T+K E+ ++ L
Sbjct: 718  QSLENISQKCSGS-------EKQCGELK-SEVTDLTQKLSL----LKEKTQKQEVTIDTL 765

Query: 335  NCQIRQTNKELENKLATMGTESKA-----VSSPSKKGSPLISRKSGRN-TASKMKSPWSQ 388
              ++ QTN+EL+ KL T   E +A     + S  ++   L      ++   S +    S+
Sbjct: 766  QTEVDQTNEELD-KLNTAYLEERAQLIHDLQSCEREIDSLKDVLLEKDKEISVLSGNISE 824

Query: 389  LSSETLNQDTDKKINKNEIAKLEMVIQSLNKDL-VDKEYVISEKDTXXXXXXXXXXG-KD 446
             + + +    D K+ ++ + ++E  +    +++ + +E   S++ T            KD
Sbjct: 825  YTEQLIALKQDLKMKEDNLIQVENALSKAEREVSILRESQNSDQRTLENKITELMENLKD 884

Query: 447  T---LIAQLQLEHQQHMEGPSLI-HVGTNTEDVNEI-AKVQEQLKQELND----EIKDVN 497
            T   L+    L   +  E  +L+     + + + E+  ++Q+QL+   +     E+   +
Sbjct: 885  TEMELLKARDLRDSKTAEVETLVKQADDDKKAIQELRGEIQKQLQSHCHHLSECEMHIAS 944

Query: 498  VKDLI----EKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDS 553
            +K+ +    +KL+ A E   Q +++  +  K +   K        Q++K  +    VS  
Sbjct: 945  LKEQLMSSAQKLQEALELQQQFSNKEQSFEKELKSSKDEQNRLCSQVEKYRNEMHVVSQQ 1004

Query: 554  NKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRL 613
             +E  R TE++  +  ++ E E+   +L++ L   ++G  +E +  +    ++     R 
Sbjct: 1005 LEEQTR-TEDI--IRGEMKEKEQIIASLEIQL--KEAGAQVEEERQRFEDALKTRDSERE 1059

Query: 614  KAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSA 673
            K  S L+S+  ++    ++L    +E +    ++  L  +    +     L+EQ+ +   
Sbjct: 1060 KMSSDLQSKSENISNLQNLLNSLKNEKKQLQENLEALTGEFEMQKQNVHQLKEQVTSALD 1119

Query: 674  SKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKIS 733
            S       ++ L  +  +L   +    +D +  +++L+   +   D    LE+  ++  +
Sbjct: 1120 SNASYQNQVQQLSAEAARLQQEL----SDSQITISELRCEKESLRDEVSVLERQVSQNST 1175

Query: 734  ELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRY 793
             + A    +E+  +Q       ++Q     ++ ++S+++     +  L+ ++   + R  
Sbjct: 1176 VIEALQKDKEELTLQNSELSRGRVQSLTSKVDQLQSDVAGKDGTLGNLQMTMEAQQKRLM 1235

Query: 794  SLERKADQLGSYLQEKQKAYSEYTIQEDELVNR---LAVLMDHDRVVEKQLLEIEHENKE 850
             L+ +   L S L+EK++ + E    + E  N    +  L      + +Q  ++  + K 
Sbjct: 1236 QLQEEESSLKSQLREKEEVWKENQCLKSEASNHKITVCSLQAEAESLREQHSQVCQQIKN 1295

Query: 851  LQKKNQILLEENQNLQISLSDMQQHYNALVE-----KANRTDLAESESTKYQTQLRDLES 905
             ++  + +  + Q  +  L+   +   +L E     + N  +L ES++   + ++  L+S
Sbjct: 1296 GEETLRNVKHQCQKHKEELNVTNETIKSLTEQIGVLEGNAREL-ESDAELRRGEVVKLQS 1354

Query: 906  NLKRITHEHQTL---IVQKKKEI---EDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQ 959
            +++  T E+  L      K+KE+     + ++ N Q+E A+      N  +   +  +T+
Sbjct: 1355 HIQAATEENHQLRAACESKEKELAHHSQVLLDLNGQLEKALEQ----NSSFSATVNILTE 1410

Query: 960  LEAQLQEYKNNIENLNMNVEELN--KMNLELIDKHVQKQQTQSPDYTEQYINEINKLNAL 1017
               +LQE    +      V ELN  K +L+ +   ++KQ ++     ++ + E  +L A 
Sbjct: 1411 NNQRLQE---ELAQKEKAVSELNADKSSLQELLSGLEKQISEDRQAIDRLLKEKEEL-AT 1466

Query: 1018 LKQKDEEIIALNQKINNAQVSYMSMVSDYESK-LAQFTTKLENMEEEMQRVSKQLLDSKQ 1076
                 ++++  +++ N+A +   +   +  SK L +    L+N+ EE   + KQ+ +  +
Sbjct: 1467 AADGFKKVLQESEQSNSAGLLQKTNECEALSKVLKEKEGWLQNLREEADGLKKQVAELTE 1526

Query: 1077 ---HNEELQILVREQ-DDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXX 1132
                 E+  +  R Q +D+  EL   +L   + + + +  ++ S I  M  DA       
Sbjct: 1527 MFTQKEQTALAQRSQLEDKQNEL--LQLHDAIRVLQEQESVLRSGI--MEKDA------- 1575

Query: 1133 XXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVN 1192
                      +   + E  +E+SV+ +  A+L T   +C    +QL+    E      ++
Sbjct: 1576 --LIQQGAEERQVYQREISREKSVVSQLQAELETVRGDCAEAQLQLQQREEEFQ----MS 1629

Query: 1193 QEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQK 1252
            ++++N+    +  L+++         E+   +    D+      EL +Q  A+   D   
Sbjct: 1630 RDELNKQTQSVVLLSSQLGEANERAREMEVRVQKLADEHRLLTREL-EQRNAE-ATDLTD 1687

Query: 1253 TEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLR---NL 1309
                L+ Q +AF+S+ ++ + ++  S +E T        +  LQ  LQ+K+E LR    L
Sbjct: 1688 DAQALKEQSAAFKSELQKTVTALARSQEEVTRLKTECSGLERLQGILQEKDEALRQKDTL 1747

Query: 1310 QEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILN 1369
             ++  D + +++ +  +  D+ V                   + +       +Q  S+  
Sbjct: 1748 VQQLNDSMAELDKMLKQKTDDAVGQSAKISDLEDSVCRLRDQVDSSGLEVSTLQ-HSLKQ 1806

Query: 1370 INEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQ 1429
              E + + +  S               + +AK +E +  L+ K   + +   +   TL  
Sbjct: 1807 KEELSLEWQSQSAAAVQTLG------TNLQAKEVECS-SLKEKVFHLEESVEKLNNTLQA 1859

Query: 1430 RNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIE 1489
            +  E E++++ L + +  + D  ++   ++     +  + A  ++T   ES     +L  
Sbjct: 1860 QTSEVEDLKRVLGQKDVALSD-QFKCLQDVQ----RRADEALLFKTQFTESAELVSQLQS 1914

Query: 1490 ELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRA 1549
            +L+   T+S  L K   E   A      K       L++   ++    DE++ LQ ++  
Sbjct: 1915 QLHSLSTDSEHLKKSAEETQSAFNNLREKYAANLEELQDARRQLSQRMDEVSGLQKLLDD 1974

Query: 1550 SSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDLAMYMLHQRDV 1601
            S+ + ++  S     +             E L+A    E D A+ + HQ +V
Sbjct: 1975 SARQRERASSTTETLRSELSAVCQKLEEAEDLNAKLSKEKDEAL-VSHQANV 2025



 Score =  110 bits (265), Expect = 3e-22
 Identities = 278/1512 (18%), Positives = 637/1512 (42%), Gaps = 147/1512 (9%)

Query: 144  VTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKD-QIIEAKNKAT--TXXXXXX 200
            V+ L  ++  K+     +  K+   E ++ ++ +K +  + Q  E K++ T  T      
Sbjct: 692  VSSLRESLSLKETQFKEVSDKLLQTEQSLENISQKCSGSEKQCGELKSEVTDLTQKLSLL 751

Query: 201  XXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLL 260
                       +  + ++ +  E    +   + +E+ +L+ D++S +  I SL++   LL
Sbjct: 752  KEKTQKQEVTIDTLQTEVDQTNEELDKLNTAYLEERAQLIHDLQSCEREIDSLKDV--LL 809

Query: 261  EAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAK-QSIEPSCEEKTEI--EEKGSLE 317
            E  + EIS+    +++  EQ              L + ++     E +  I  E + S +
Sbjct: 810  EKDK-EISVLSGNISEYTEQLIALKQDLKMKEDNLIQVENALSKAEREVSILRESQNSDQ 868

Query: 318  IANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRN 377
                 ++T+ +E L+    ++ +     ++K A + T  K      K    L      + 
Sbjct: 869  RTLENKITELMENLKDTEMELLKARDLRDSKTAEVETLVKQADDDKKAIQELRGEIQKQL 928

Query: 378  TASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXX 437
             +        ++   +L +       K + A LE+  Q  NK+   ++ + S KD     
Sbjct: 929  QSHCHHLSECEMHIASLKEQLMSSAQKLQEA-LELQQQFSNKEQSFEKELKSSKDEQNRL 987

Query: 438  XXXXXXGKDTL-IAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDV 496
                   ++ + +   QLE Q   E    I  G   E    IA ++ QLK E   ++++ 
Sbjct: 988  CSQVEKYRNEMHVVSQQLEEQTRTED---IIRGEMKEKEQIIASLEIQLK-EAGAQVEEE 1043

Query: 497  NVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKS---NHKLKLKQMQKTIDNFSKVSDS 553
              +   + LK+ + +  +++ ++ + ++N+  +++   + K + KQ+Q+ ++  +   + 
Sbjct: 1044 RQR-FEDALKTRDSEREKMSSDLQSKSENISNLQNLLNSLKNEKKQLQENLEALTGEFEM 1102

Query: 554  NKEIVRLTEELHHLSQKVAELEEEKGNLQ--LHLVDYDSGRMIE--SDVYKKMIEMENLA 609
             K+ V      H L ++V    +   + Q  +  +  ++ R+ +  SD    + E+    
Sbjct: 1103 QKQNV------HQLKEQVTSALDSNASYQNQVQQLSAEAARLQQELSDSQITISELRCEK 1156

Query: 610  ETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQID 669
            E+    +S+LE Q       +  LQ+  +E+  + +++S+ +   + S++      +Q+ 
Sbjct: 1157 ESLRDEVSVLERQVSQNSTVIEALQKDKEELTLQNSELSRGRVQSLTSKV------DQLQ 1210

Query: 670  ALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSA 729
            +  A K      + NL++  E     +  L+ ++  + ++L+   +E +   ++  K  A
Sbjct: 1211 SDVAGKDG---TLGNLQMTMEAQQKRLMQLQEEESSLKSQLRE--KEEVWKENQCLKSEA 1265

Query: 730  EKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVME 789
                  +  +  E +S  +    +  +I+  +  + N++ +  K+K  +    E+I  + 
Sbjct: 1266 SNHKITVCSLQAEAESLREQHSQVCQQIKNGEETLRNVKHQCQKHKEELNVTNETIKSLT 1325

Query: 790  DRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENK 849
            ++   LE  A +L S          +  ++  E+V   + +        +     E + K
Sbjct: 1326 EQIGVLEGNARELES----------DAELRRGEVVKLQSHIQAATEENHQLRAACESKEK 1375

Query: 850  ELQKKNQILLEENQNLQISL---SDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESN 906
            EL   +Q+LL+ N  L+ +L   S      N L E   R     ++  K  ++L   +S+
Sbjct: 1376 ELAHHSQVLLDLNGQLEKALEQNSSFSATVNILTENNQRLQEELAQKEKAVSELNADKSS 1435

Query: 907  LKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKN----IEYVTQLEA 962
            L+ +    +  I + ++ I+ L  E      +A   KKVL E  + N    ++   + EA
Sbjct: 1436 LQELLSGLEKQISEDRQAIDRLLKEKEELATAADGFKKVLQESEQSNSAGLLQKTNECEA 1495

Query: 963  Q---LQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYT--EQYINEINKLNAL 1017
                L+E +  ++NL    + L K   EL +   QK+QT     +  E   NE+ +L+  
Sbjct: 1496 LSKVLKEKEGWLQNLREEADGLKKQVAELTEMFTQKEQTALAQRSQLEDKQNELLQLHDA 1555

Query: 1018 LK--QKDEEII--------ALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRV 1067
            ++  Q+ E ++        AL Q+    +  Y   +S  +S ++Q   +LE +  +    
Sbjct: 1556 IRVLQEQESVLRSGIMEKDALIQQGAEERQVYQREISREKSVVSQLQAELETVRGDCAEA 1615

Query: 1068 SKQLLDSKQH--------NEELQILVREQDDQIKELKETKLTFEMNIPKT--EGMIISST 1117
              QL   ++         N++ Q +V     Q+ E  E     E+ + K   E  +++  
Sbjct: 1616 QLQLQQREEEFQMSRDELNKQTQSVVL-LSSQLGEANERAREMEVRVQKLADEHRLLTRE 1674

Query: 1118 IEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQ 1177
            +E  + +A ++              K  E ++ +   +  QE+  +L TE          
Sbjct: 1675 LEQRNAEATDLTDDAQALKEQSAAFK-SELQKTVTALARSQEEVTRLKTECSGLERLQGI 1733

Query: 1178 LETLNTELTGHDVVNQEQINQLKSKLEQ-LNTENDNLL---STVAELRSSIS---SAVDQ 1230
            L+  +  L   D + Q Q+N   ++L++ L  + D+ +   + +++L  S+      VD 
Sbjct: 1734 LQEKDEALRQKDTLVQ-QLNDSMAELDKMLKQKTDDAVGQSAKISDLEDSVCRLRDQVDS 1792

Query: 1231 RGFEIAELW-----KQHLA-----QREADFQKTEHELR---VQLSAFESKYEQLLDSVQ- 1276
             G E++ L      K+ L+     Q  A  Q     L+   V+ S+ + K   L +SV+ 
Sbjct: 1793 SGLEVSTLQHSLKQKEELSLEWQSQSAAAVQTLGTNLQAKEVECSSLKEKVFHLEESVEK 1852

Query: 1277 --SSTQEETNKIVTMEQVTSLQN-KLQDKEEHLRNLQEKY-------------ADVINQI 1320
              ++ Q +T+++  +++V   ++  L D+ + L+++Q +              A++++Q+
Sbjct: 1853 LNNTLQAQTSEVEDLKRVLGQKDVALSDQFKCLQDVQRRADEALLFKTQFTESAELVSQL 1912

Query: 1321 EI----LRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQ-----SILNIN 1371
            +     L ++ E  K +                 +L     + +Q+ ++      +  + 
Sbjct: 1913 QSQLHSLSTDSEHLKKSAEETQSAFNNLREKYAANLEELQDARRQLSQRMDEVSGLQKLL 1972

Query: 1372 EENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRN 1431
            +++A+ ++ +             V     +  +L  +L  K+ +    +H+  ++L    
Sbjct: 1973 DDSARQRERASSTTETLRSELSAVCQKLEEAEDLNAKLS-KEKDEALVSHQANVSLL--T 2029

Query: 1432 DEFENVRQQLVEYEKRIEDLTYEKES-ELAILRLKMHENANHYETMQKESEIERVKLIEE 1490
             E E ++ Q ++   ++  LT   E  E+A+  +    +  +  T Q  SE+++   +EE
Sbjct: 2030 VEIEKLKSQYLQVATQLNVLTENLEQREMALHAINSQYSLQNKNTSQLVSEMQK---LEE 2086

Query: 1491 LNVKITESVSLNKQ--------VAELNKALEEEVAKTNEMQTALENQEIEI-VTLNDEIT 1541
            +N ++ E ++L+K+        V+  N  L+EE +K+   +  LEN+  ++ + + +E +
Sbjct: 2087 VNQRLKEEIALSKEENRKLLTAVSCENAHLKEEFSKSLAEKKELENRCHQMRLQMEEECS 2146

Query: 1542 NLQNMVRASSSK 1553
            +L+ M+   +S+
Sbjct: 2147 SLKEMMERVTSE 2158



 Score =  107 bits (258), Expect = 2e-21
 Identities = 274/1457 (18%), Positives = 572/1457 (39%), Gaps = 136/1457 (9%)

Query: 144  VTHLSNTIKEKDNALSVLQVKMKIMETTILDLQE-------KINEKDQIIEAKNKATTXX 196
            V  L + +  KD  L  LQ+ M+  +  ++ LQE       ++ EK+++ + +N+     
Sbjct: 1206 VDQLQSDVAGKDGTLGNLQMTMEAQQKRLMQLQEEESSLKSQLREKEEVWK-ENQCLKSE 1264

Query: 197  XXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDV---RISSL 253
                           E  ++Q +++ +     E   ++ K +  K  E  +V    I SL
Sbjct: 1265 ASNHKITVCSLQAEAESLREQHSQVCQQIKNGEETLRNVKHQCQKHKEELNVTNETIKSL 1324

Query: 254  EEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEK-TEIEE 312
             E   +LE    E+  +      EL +                   +  +CE K  E+  
Sbjct: 1325 TEQIGVLEGNARELESD-----AELRRGEVVKLQSHIQAATEENHQLRAACESKEKELAH 1379

Query: 313  KGSLEIANMTELTKKIELLEHLNCQIR---QTNKELENKLATMGTESKAVSSPSKKGSPL 369
               + +    +L K +E     +  +    + N+ L+ +LA    + KAVS  +   S L
Sbjct: 1380 HSQVLLDLNGQLEKALEQNSSFSATVNILTENNQRLQEELA---QKEKAVSELNADKSSL 1436

Query: 370  ISRKSG-RNTASKMKSPWSQLSSE-----TLNQDTDKKINKNEIAKLEMVIQSLNK-DLV 422
                SG     S+ +    +L  E     T      K + ++E +    ++Q  N+ + +
Sbjct: 1437 QELLSGLEKQISEDRQAIDRLLKEKEELATAADGFKKVLQESEQSNSAGLLQKTNECEAL 1496

Query: 423  DKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQ 482
             K  V+ EK+           G    +A+L  E     E  +L       +  NE+ ++ 
Sbjct: 1497 SK--VLKEKEGWLQNLREEADGLKKQVAEL-TEMFTQKEQTALAQRSQLEDKQNELLQLH 1553

Query: 483  EQLK--QELNDEI------KDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHK 534
            + ++  QE    +      KD  ++   E+ +  + +I++    +      +  V+ +  
Sbjct: 1554 DAIRVLQEQESVLRSGIMEKDALIQQGAEERQVYQREISREKSVVSQLQAELETVRGDCA 1613

Query: 535  LKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDY-DSGRM 593
                Q+Q+  + F     S  E+ + T+ +  LS ++ E  E    +++ +    D  R+
Sbjct: 1614 EAQLQLQQREEEFQM---SRDELNKQTQSVVLLSSQLGEANERAREMEVRVQKLADEHRL 1670

Query: 594  IESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSD 653
            +  ++ ++  E  +L +          + K +L + +  L +  +EV     + S L+  
Sbjct: 1671 LTRELEQRNAEATDLTDDAQALKEQSAAFKSELQKTVTALARSQEEVTRLKTECSGLERL 1730

Query: 654  QVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNY 713
            Q   + K   L ++   +      +A + + LK   +   G    + +D ED + +L++ 
Sbjct: 1731 QGILQEKDEALRQKDTLVQQLNDSMAELDKMLKQKTDDAVGQSAKI-SDLEDSVCRLRDQ 1789

Query: 714  IQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSK 773
            +             S  ++S L   +  +E+  ++ Q    A +Q     ++  E E S 
Sbjct: 1790 VDS-----------SGLEVSTLQHSLKQKEELSLEWQSQSAAAVQTLGTNLQAKEVECSS 1838

Query: 774  YKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYS-EYTIQEDELVNRLAVLMD 832
             K ++  LEES+  + +   +   + + L   L +K  A S ++   +D  V R A   D
Sbjct: 1839 LKEKVFHLEESVEKLNNTLQAQTSEVEDLKRVLGQKDVALSDQFKCLQD--VQRRA---D 1893

Query: 833  HDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEK--ANRTDLAE 890
               + + Q  E      +LQ +   L  ++++L+ S  + Q  +N L EK  AN  +L +
Sbjct: 1894 EALLFKTQFTESAELVSQLQSQLHSLSTDSEHLKKSAEETQSAFNNLREKYAANLEELQD 1953

Query: 891  S---------ESTKYQTQLRDLESNLKRITHEHQTL------IVQKKKEIEDLEIEFNTQ 935
            +         E +  Q  L D     +R +   +TL      + QK +E EDL  + + +
Sbjct: 1954 ARRQLSQRMDEVSGLQKLLDDSARQRERASSTTETLRSELSAVCQKLEEAEDLNAKLSKE 2013

Query: 936  IESAIRDKKVLNEKYEKNIEYVT-QLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQ 994
             + A+         ++ N+  +T ++E    +Y      LN+  E L +  + L    + 
Sbjct: 2014 KDEAL-------VSHQANVSLLTVEIEKLKSQYLQVATQLNVLTENLEQREMAL--HAIN 2064

Query: 995  KQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMS-----MVSDYESK 1049
             Q +     T Q ++E+ KL   + Q+ +E IAL+++ N   ++ +S     +  ++   
Sbjct: 2065 SQYSLQNKNTSQLVSEMQKLEE-VNQRLKEEIALSKEENRKLLTAVSCENAHLKEEFSKS 2123

Query: 1050 LAQFTTKLEN--------MEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLT 1101
            LA+   +LEN        MEEE   + + +       + +Q  V  QD ++ +LKE    
Sbjct: 2124 LAE-KKELENRCHQMRLQMEEECSSLKEMMERVTSERDGIQTKVSVQDQELCQLKENLQK 2182

Query: 1102 FEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQS 1161
             E  +  +E   +   +        N+              K  + +   Q+   LQE+ 
Sbjct: 2183 VEQVLQDSEREWL--FVLDREKQEKNLLVEQLKSVENEMKSKDIKVDALKQDLDGLQEKL 2240

Query: 1162 AKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELR 1221
            A  ++ +++      QL     E +    V++ Q+ ++ + +++   EN  L   +   +
Sbjct: 2241 ALASSAIRQGSD---QLSAKELEAS----VSRVQLEKVLASVQEKEFENSRLKEALNAAQ 2293

Query: 1222 SSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQE 1281
              + + + +RGF I         +R       +  L+  ++  E+ ++  +D++ S   +
Sbjct: 2294 HQLHALLQKRGFSICA-----PGERSPALSDEQVSLQNMITRLEASHQGEVDTLNSDLNQ 2348

Query: 1282 ETNKIVTMEQVTSLQNKLQDKEEH-LRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXX 1340
                +   EQ+     +  D+++H    LQ K   + +Q   L +E+E  K A       
Sbjct: 2349 TVAHLKRTEQMLHEGERCSDEKDHQTALLQTKVEQLQSQ---LSAEVERAKDAAVTLSCL 2405

Query: 1341 XXXXXXXXXXDLRTENQSYKQM-----QEQSILNINEENAQLKKSSXXXXXXXXXXXXRV 1395
                        R   Q  +Q+       Q +L+ +   AQ+ +S+             V
Sbjct: 2406 NSELREKGDQIGRMNIQISQQLLLLADLSQQLLDKDASIAQVMESAANERIKTREENSAV 2465

Query: 1396 NDAEAKVLELTHQLELK---DSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLT 1452
               + + LE  H    K   + E   +  E      +   E + +   L E E+R+   T
Sbjct: 2466 -VGQLQSLEQEHATSAKRKGNLETEGQITEQKAQSERLQSEKQLLESTLNEKEQRLSQ-T 2523

Query: 1453 YEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKAL 1512
             +  +E + L  ++   A   +   ++   + ++ +E+L  +I  + S      E     
Sbjct: 2524 LQTLTEKSFLLEQLQAGAAEKDAAAEQERKDWMQKLEQLQKEIQNASSTASAAVE---EA 2580

Query: 1513 EEEVAKTNEMQTALENQ 1529
            E+E+A+    +T LE +
Sbjct: 2581 EKELAQVTHEKTKLEKK 2597



 Score = 97.5 bits (232), Expect = 3e-18
 Identities = 261/1435 (18%), Positives = 593/1435 (41%), Gaps = 124/1435 (8%)

Query: 216  QQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLA 275
            Q++ +++EN   +E   +D ++  L  ++ +    + L E  K +E       ++   L 
Sbjct: 2171 QELCQLKENLQKVEQVLQDSEREWLFVLDREKQEKNLLVEQLKSVENEMKSKDIKVDALK 2230

Query: 276  QELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLN 335
            Q+L+               LA  +I    ++ +  E + S+    + ++   ++  E  N
Sbjct: 2231 QDLD--------GLQEKLALASSAIRQGSDQLSAKELEASVSRVQLEKVLASVQEKEFEN 2282

Query: 336  CQIRQTNKELENKL-ATMGTESKAVSSPSKKGSPLISRK--SGRNTASKMKSPWSQLSSE 392
             ++++     +++L A +     ++ +P ++ SP +S +  S +N  +++++   Q   +
Sbjct: 2283 SRLKEALNAAQHQLHALLQKRGFSICAPGER-SPALSDEQVSLQNMITRLEAS-HQGEVD 2340

Query: 393  TLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTX-----XXXXXXXXXGKDT 447
            TLN D ++ +    + + E ++    +   +K++  +   T                KD 
Sbjct: 2341 TLNSDLNQTVA--HLKRTEQMLHEGERCSDEKDHQTALLQTKVEQLQSQLSAEVERAKDA 2398

Query: 448  LIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKS 507
             +    L  +   +G     +G     +++   +   L Q+L D  KD ++  ++E   +
Sbjct: 2399 AVTLSCLNSELREKGDQ---IGRMNIQISQQLLLLADLSQQLLD--KDASIAQVMES--A 2451

Query: 508  AEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHL 567
            A E+I +  +E  A    +  ++  H    K+ +  ++   ++++   +  RL  E   L
Sbjct: 2452 ANERI-KTREENSAVVGQLQSLEQEHATSAKR-KGNLETEGQITEQKAQSERLQSEKQLL 2509

Query: 568  SQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKA-ISLLESQKFDL 626
                + L E++  L   L        +   +     E +  AE   K  +  LE  + ++
Sbjct: 2510 E---STLNEKEQRLSQTLQTLTEKSFLLEQLQAGAAEKDAAAEQERKDWMQKLEQLQKEI 2566

Query: 627  VQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLK 686
                       +E E +LA ++  +  ++  ++ +  L  +     A ++E  L  E  +
Sbjct: 2567 QNASSTASAAVEEAEKELAQVTH-EKTKLEKKVHAALLARKETTKKAHEREKKLTQELTE 2625

Query: 687  LDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSK 746
            L +E  Y  + + +  + + +N LQ   ++ +   ++L K S     EL A +    Q +
Sbjct: 2626 LKEE--YQALLEQQRQQTNDLNALQFNFEKKVKEVEELNKTSLSDQDEL-ASLKQLMQER 2682

Query: 747  IQTQFGIDAKIQERDLY---IENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLG 803
             ++   +   + ER++    + N++ EL   KS+I ++ E +A  ++     E+ A+ L 
Sbjct: 2683 DKSLQDLKKTMGEREIQSQSLPNLQMELENLKSQIGKMYEELASKDEALTVGEQGAEALK 2742

Query: 804  SYLQEKQK----AYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILL 859
            S L   +K    A +E   + D+   R   L   +  V+++   +  E   L+ +  +L 
Sbjct: 2743 SKLLTAEKHLEEAQAEIKEKTDQAEERRDALKAFELRVQQEKHVLISEKDALESRLNLLE 2802

Query: 860  EENQNLQISLSDMQQHYNALVEKANRTDLA---ESESTKYQTQLRD-LESNLKRITH--E 913
               Q+   + + +++      EK    D+    ++E+T   ++L+D + S  K++    +
Sbjct: 2803 SALQHHTETAAALEETRLQCAEKQRSLDVLKREQAEATALISELKDEISSANKKLAEFAK 2862

Query: 914  HQTLIVQKKKEI------------EDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLE 961
             +T  V K +              E+L+I+   + E+ +  K  L+EK E       QL+
Sbjct: 2863 DKTCAVCKTRRDDQDGPCFSCQRHENLQIKLKEREEAFLMSKAQLSEKEELIAALELQLQ 2922

Query: 962  AQLQEYKNNIENLNMNVEELNKM--NLELIDKHVQKQ---QTQSPDYTEQYINEINKLNA 1016
             Q+  ++ ++E +     EL +   N  + D+  Q +    T+          E+ K N+
Sbjct: 2923 QQIGAHEASMERVKTEAAELQRSQHNGTVNDQDNQSKIAALTRKLQAALLSRKELIKENS 2982

Query: 1017 LLKQKDEEIIALNQKINNAQVSYM-SMVSDYESKLAQFTTKLENMEEEMQRVSKQL--LD 1073
             LKQ D +  A  ++    + S + + + + + +  +  +   +   +  R+  ++  L 
Sbjct: 2983 ALKQ-DVKRQADKERAKELEFSSLEAALEEIKRQNMELESSASSASRDKDRLRGEVDQLL 3041

Query: 1074 SKQHN-----EELQILVR---EQDD----QIKELKETKLTFEMNIPKTEGMIISSTIEPM 1121
            S  H+     + L++ +    +Q +    Q++ LK+++ T E++  K++   +    E +
Sbjct: 3042 SDNHSLSAACDSLKLTIENITQQKEAFSCQLESLKDSQ-TDELSKWKSKHAELKQEYESL 3100

Query: 1122 SDDANNVDXXXXXXXXXXXXLKVQEEEEFIQ------ERSVLQEQSAKLNTE---LQE-- 1170
                 N+              K  ++E   +      ER VL++Q AKL  E   ++E  
Sbjct: 3101 LQSYENISSEMEKMRQVLEATKRDQQEAIKKAHHLEAERDVLEKQVAKLEEEQEGIKEKM 3160

Query: 1171 ---CYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSA 1227
                  K+ ++E L  E         E     ++++ +L   N  L + + +L++S S  
Sbjct: 3161 RKFSKEKLCKVEELEEENRNTRRELTELTENHRTEVSELTDRNRQLEAEICKLKAS-SEE 3219

Query: 1228 VDQRGFEIAELWKQHLAQ-READF--QKTEHELRVQLSAFESKYEQLL---DSVQSSTQE 1281
            +D++  E+    K+  A+  EA +  +K   E +   S+ + K ++ L   +S+ +  + 
Sbjct: 3220 LDEKLSELHSENKEMAAKLEEATYTLEKASTESKTYTSSVQLKLDEALGLSNSLTAQMET 3279

Query: 1282 ETNKI-VTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXX 1340
            +T+++   ME   SLQ + Q   + L  +Q  +   + + +++  E+ D           
Sbjct: 3280 QTSELGAQMEVNNSLQKEKQSLCQQLEKMQNDHELQLGKKDVVIQELRDVISGHSQETVS 3339

Query: 1341 XXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEA 1400
                      D     +  + +QE S   +  EN  L+  +             +   +A
Sbjct: 3340 LNEKVRILEDDKSLLQEELENVQEISD-KVKNENEYLETVALRNSEKIDELTESIALLQA 3398

Query: 1401 KVLELTHQL-ELKD--SEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKES 1457
            + +EL+ QL   KD  +++ Q+  E  + L +   EFE   + +    +R  + +     
Sbjct: 3399 QKMELSSQLAATKDMNNQVRQEKEEEQLRLVR---EFEGKLKTV----QRGNEGSKNVNK 3451

Query: 1458 ELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVA 1517
            EL  L  + H+  N  +    ++ I   ++I EL    + S S      EL + L++   
Sbjct: 3452 ELQELLKEKHQEINQLQ----QNCIRYQEVILELE---SSSKSSQAVAEELKRELKKSSE 3504

Query: 1518 KTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQL 1572
            + + +Q      E E+    D +   +  + +  S+  +  S  S + +  D Q+
Sbjct: 3505 ELSALQQKCGRAEAELSVQRDLLLQAKEKLLSVESERDQMASHVSQSSRRPDNQV 3559



 Score = 94.3 bits (224), Expect = 2e-17
 Identities = 276/1468 (18%), Positives = 592/1468 (40%), Gaps = 137/1468 (9%)

Query: 147  LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXX 206
            L++ ++EK + +  + +++      + DL +++ +KD  I    ++              
Sbjct: 2405 LNSELREKGDQIGRMNIQISQQLLLLADLSQQLLDKDASIAQVMESAANERIKTREENSA 2464

Query: 207  XXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKD-IES-KDVRISSLEEANKLLEAAR 264
                 +  +Q+     +    +E E +  +Q+   + ++S K +  S+L E  + L +  
Sbjct: 2465 VVGQLQSLEQEHATSAKRKGNLETEGQITEQKAQSERLQSEKQLLESTLNEKEQRL-SQT 2523

Query: 265  FEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEE-------KTEIEEKGSLE 317
             +   E S L ++L+                  Q +E   +E        +   E+   E
Sbjct: 2524 LQTLTEKSFLLEQLQAGAAEKDAAAEQERKDWMQKLEQLQKEIQNASSTASAAVEEAEKE 2583

Query: 318  IANMTELTKKIELLEHLNCQIR-QTNK---ELENKLATMGTESKAVSSPSKKGSPLISRK 373
            +A +T    K+E   H     R +T K   E E KL    TE K      +  + L  ++
Sbjct: 2584 LAQVTHEKTKLEKKVHAALLARKETTKKAHEREKKLTQELTELK-----EEYQALLEQQR 2638

Query: 374  SGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDT 433
               N  + ++  + +   E    +     +++E+A L+ ++Q  +K L D +  + E++ 
Sbjct: 2639 QQTNDLNALQFNFEKKVKEVEELNKTSLSDQDELASLKQLMQERDKSLQDLKKTMGEREI 2698

Query: 434  XXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVG-TNTEDVNEIAKVQEQLKQELNDE 492
                        + L +Q+   +++       + VG    E +       E+  +E   E
Sbjct: 2699 QSQSLPNLQMELENLKSQIGKMYEELASKDEALTVGEQGAEALKSKLLTAEKHLEEAQAE 2758

Query: 493  IKDV--NVKDLIEKLKSAEEQITQ----LNDEIDA--ANKNMIKVKSNH----------- 533
            IK+     ++  + LK+ E ++ Q    L  E DA  +  N+++    H           
Sbjct: 2759 IKEKTDQAEERRDALKAFELRVQQEKHVLISEKDALESRLNLLESALQHHTETAAALEET 2818

Query: 534  KLKLKQMQKTIDNFSK-VSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHL-VDYDSG 591
            +L+  + Q+++D   +  +++   I  L +E+   ++K+AE  ++K         D   G
Sbjct: 2819 RLQCAEKQRSLDVLKREQAEATALISELKDEISSANKKLAEFAKDKTCAVCKTRRDDQDG 2878

Query: 592  RMIESDVYKKM-IEMENLAETRLKAISLLESQKFDLVQELHI-LQQK-------YDEVED 642
                   ++ + I+++   E  L + + L S+K +L+  L + LQQ+        + V+ 
Sbjct: 2879 PCFSCQRHENLQIKLKEREEAFLMSKAQL-SEKEELIAALELQLQQQIGAHEASMERVKT 2937

Query: 643  KLADISQLQSDQVC----SEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKD 698
            + A++ + Q +       ++ K   L  ++ A   S+KEL      LK D ++     + 
Sbjct: 2938 EAAELQRSQHNGTVNDQDNQSKIAALTRKLQAALLSRKELIKENSALKQDVKRQADKERA 2997

Query: 699  LENDKEDIMNKLQNYIQENMDLTDKLEKMSAEK------ISELLAKINHEEQSKIQT-QF 751
             E +   +   L+   ++NM+L       S +K      + +LL+  NH   +   + + 
Sbjct: 2998 KELEFSSLEAALEEIKRQNMELESSASSASRDKDRLRGEVDQLLSD-NHSLSAACDSLKL 3056

Query: 752  GIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQK 811
             I+   Q+++ +   +ES        + + +   A ++    SL +  + + S +++ ++
Sbjct: 3057 TIENITQQKEAFSCQLESLKDSQTDELSKWKSKHAELKQEYESLLQSYENISSEMEKMRQ 3116

Query: 812  AYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHE-----------NKELQKKNQILLE 860
                    + E + +   L     V+EKQ+ ++E E           +KE   K + L E
Sbjct: 3117 VLEATKRDQQEAIKKAHHLEAERDVLEKQVAKLEEEQEGIKEKMRKFSKEKLCKVEELEE 3176

Query: 861  ENQNLQISLSDM-QQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIV 919
            EN+N +  L+++ + H   + E  +R    E+E  K +    +L+  L  +  E++ +  
Sbjct: 3177 ENRNTRRELTELTENHRTEVSELTDRNRQLEAEICKLKASSEELDEKLSELHSENKEMAA 3236

Query: 920  QKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVE 979
            + ++    LE       ES      V   K ++ +     L AQ++   + +    M V 
Sbjct: 3237 KLEEATYTLE---KASTESKTYTSSV-QLKLDEALGLSNSLTAQMETQTSEL-GAQMEVN 3291

Query: 980  ELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSY 1039
               +   + + + ++K Q        +    I +L  ++    +E ++LN+K+       
Sbjct: 3292 NSLQKEKQSLCQQLEKMQNDHELQLGKKDVVIQELRDVISGHSQETVSLNEKVR------ 3345

Query: 1040 MSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETK 1099
              ++ D +S L +   +LEN++E   +V       K  NE L+ +     ++I EL E+ 
Sbjct: 3346 --ILEDDKSLLQE---ELENVQEISDKV-------KNENEYLETVALRNSEKIDELTES- 3392

Query: 1100 LTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQE 1159
                + + + + M +SS +    D  N V               V+E E  ++      E
Sbjct: 3393 ----IALLQAQKMELSSQLAATKDMNNQVRQEKEEEQLRL----VREFEGKLKTVQRGNE 3444

Query: 1160 QSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAE 1219
             S  +N ELQE   +  + + +N +L  + +  QE I +L+S  +      + L   + +
Sbjct: 3445 GSKNVNKELQELLKE--KHQEIN-QLQQNCIRYQEVILELESSSKSSQAVAEELKRELKK 3501

Query: 1220 LRSSISSAVDQRGFEIAELWKQH--LAQREADFQKTEHELRVQLSAFESKYEQLLDS-VQ 1276
                +S+   + G   AEL  Q   L Q +      E E R Q+++  S+  +  D+ V 
Sbjct: 3502 SSEELSALQQKCGRAEAELSVQRDLLLQAKEKLLSVESE-RDQMASHVSQSSRRPDNQVL 3560

Query: 1277 SSTQ--EETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAF 1334
              TQ  ++T+  V  E V   Q ++++         +K  ++  Q++    E+   K A 
Sbjct: 3561 QETQPVQKTDSHVHKEFV--FQQQIEELILSKDGESKKVDELKRQLDSKDGEMNALKRAM 3618

Query: 1335 XXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXR 1394
                                 +  +  + +++   +NE++ QL +              R
Sbjct: 3619 KTNEAKLSALSSSPGG--AEASSLWNHLYQKA---LNEKDNQLLEQG--FVIKRFLEDMR 3671

Query: 1395 VNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYE 1454
            V D E   L +TH L+L+     +  +EY++    +  +   +     E  +  E +  +
Sbjct: 3672 VKDKEMNDLRVTH-LKLE-----RTINEYSVAAAAQQRQLFVLSADNAELSESAELMAAQ 3725

Query: 1455 -KESELAILRLKMHENANHYETMQKESEIERVKL----IEELNVKI-TESVSLNKQVAEL 1508
             K+    + RL+  +N  + +    E  + R++L     E++N     + + L  Q   L
Sbjct: 3726 VKDLSDHVERLEEDKNVQNRQLSDGEDAVSRMQLKLQHTEKINADAEAQLLLLRSQNDRL 3785

Query: 1509 NKALEEEVAKTNEMQTALENQEIEIVTL 1536
                E     T  ++T L++++ EI +L
Sbjct: 3786 QADSERLEGITVHLKTLLQSKDAEIASL 3813



 Score = 83.0 bits (196), Expect = 6e-14
 Identities = 196/1141 (17%), Positives = 485/1141 (42%), Gaps = 88/1141 (7%)

Query: 213  DTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHS 272
            + KQ+   + +++  + +E   EK R + +   +D +  ++++A+ L EA R  +  + +
Sbjct: 3092 ELKQEYESLLQSYENISSEM--EKMRQVLEATKRDQQ-EAIKKAHHL-EAERDVLEKQVA 3147

Query: 273  KLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLE 332
            KL +E E                 ++  E +   + E+ E        ++ELT +   LE
Sbjct: 3148 KLEEEQEGIKEKMRKFSKEKLCKVEELEEENRNTRRELTELTENHRTEVSELTDRNRQLE 3207

Query: 333  HLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRN---TAS-KMK----- 383
               C+++ +++EL+ KL+ + +E+K +++  ++ +  + + S  +   T+S ++K     
Sbjct: 3208 AEICKLKASSEELDEKLSELHSENKEMAAKLEEATYTLEKASTESKTYTSSVQLKLDEAL 3267

Query: 384  ----SPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXX 439
                S  +Q+ ++T       ++N +   + + + Q L K   D E  + +KD       
Sbjct: 3268 GLSNSLTAQMETQTSELGAQMEVNNSLQKEKQSLCQQLEKMQNDHELQLGKKDVVIQELR 3327

Query: 440  XXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVK 499
                G       L  + +   +  SL+      E++  + ++ +++K E N+ ++ V ++
Sbjct: 3328 DVISGHSQETVSLNEKVRILEDDKSLLQ-----EELENVQEISDKVKNE-NEYLETVALR 3381

Query: 500  DLIEKLKSAEEQITQLNDEIDAANKNMIKVKS-NHKLKLKQMQKTIDNFSKVSDSNKEIV 558
            +  EK+    E I  L  +    +  +   K  N++++ ++ ++ +    +     K + 
Sbjct: 3382 N-SEKIDELTESIALLQAQKMELSSQLAATKDMNNQVRQEKEEEQLRLVREFEGKLKTVQ 3440

Query: 559  RLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISL 618
            R  E   ++++++ EL +EK + +++ +  +  R  E      ++E+E+ +++       
Sbjct: 3441 RGNEGSKNVNKELQELLKEK-HQEINQLQQNCIRYQE-----VILELESSSKSSQAVAEE 3494

Query: 619  LESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKEL 678
            L+ +     +EL  LQQK    E   A++S  +   + ++ K + +E + D +++   + 
Sbjct: 3495 LKRELKKSSEELSALQQKCGRAE---AELSVQRDLLLQAKEKLLSVESERDQMASHVSQS 3551

Query: 679  ALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYI---QENMDLTDKLEKMSAEKISEL 735
            +   +N  L + Q         + +     +++  I          D+L++    K  E+
Sbjct: 3552 SRRPDNQVLQETQPVQKTDSHVHKEFVFQQQIEELILSKDGESKKVDELKRQLDSKDGEM 3611

Query: 736  --LAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAV---MED 790
              L +     ++K+          +   L+    +  L++  +++  LE+   +   +ED
Sbjct: 3612 NALKRAMKTNEAKLSALSSSPGGAEASSLWNHLYQKALNEKDNQL--LEQGFVIKRFLED 3669

Query: 791  RRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKE 850
             R   +   D   ++L + ++  +EY++       +L VL   +  + +    +  + K+
Sbjct: 3670 MRVKDKEMNDLRVTHL-KLERTINEYSVAAAAQQRQLFVLSADNAELSESAELMAAQVKD 3728

Query: 851  LQKKNQILLEENQNLQ-ISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKR 909
            L    +  LEE++N+Q   LSD +   + +  K   T+   +++      LR     L+ 
Sbjct: 3729 LSDHVE-RLEEDKNVQNRQLSDGEDAVSRMQLKLQHTEKINADAEAQLLLLRSQNDRLQA 3787

Query: 910  ITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKN 969
             +   + + V  K  ++  + E  + +  + RD ++     +    + +Q  A      +
Sbjct: 3788 DSERLEGITVHLKTLLQSKDAEIASLL--SCRDGQMSGYIQQLQANHRSQAAAYEDRLAS 3845

Query: 970  NIENLNMNVEELNKMNLELIDKHVQ-KQQTQSPDYTEQYINEINKLNALLKQKDEEIIAL 1028
                    V+EL ++  +L    VQ  + +Q  + T   +    +  A L+ + E +I+ 
Sbjct: 3846 LGHRREAAVKELRRLEAKLRHLQVQVDRSSQEREQTAVKMESFKESMASLQSERERLISQ 3905

Query: 1029 NQKI-----NNAQVSYMSMVS-DYESKLAQFTTKLENMEEEMQRVSKQLLDSKQ------ 1076
             + +      +   S   +VS   + ++ +   +++++  E   +  QL+  ++      
Sbjct: 3906 QRTLATTGGKDGAASGERLVSKGMKQEIRKLLNQMDDLNSENAMLRAQLVRYREDLNQVL 3965

Query: 1077 --HNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXX 1134
               + +L++L+++Q D I+ L+  K   E    +T   I     E  +  A         
Sbjct: 3966 SLKDNQLKVLLQKQQDVIRNLEHQKAAAEKRHRETRLEIQRRGEESGALAAEISQLKDRV 4025

Query: 1135 XXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQE 1194
                   L ++ +     E  V+ +    +  +  EC    +Q + L ++ T  D + QE
Sbjct: 4026 ATQEAEILTLRNQRSATNEGRVIADLQDAVAVKAAEC--SHLQ-QNLLSQRTLTDGL-QE 4081

Query: 1195 QINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQH--LAQREADFQK 1252
            QI  L+ + +Q++          AE +    S +D  G E+  + ++     QR A+  K
Sbjct: 4082 QIQLLEKEKKQMS----------AEAKDKGKSQIDAFGREVEGMRRERETAEQRAAELAK 4131

Query: 1253 TEHELRVQLSAFESK------YEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHL 1306
             + +L+ +LS  +++        + L    ++ Q++ ++++  E   +L+N+  ++    
Sbjct: 4132 DQLQLQQKLSESDTRSRNTRLQNESLCKAMAALQDDRDQLI--EDFKTLRNRYDEELRET 4189

Query: 1307 R 1307
            R
Sbjct: 4190 R 4190



 Score = 45.6 bits (103), Expect = 0.011
 Identities = 63/350 (18%), Positives = 144/350 (41%), Gaps = 37/350 (10%)

Query: 506  KSAEEQITQLNDEIDAANKNMIKVKSN---HKLKLKQMQKTIDNFSKVS-DSNKEIVRLT 561
            K  +++I +L +++D  N     +++    ++  L Q+    DN  KV     ++++R  
Sbjct: 3927 KGMKQEIRKLLNQMDDLNSENAMLRAQLVRYREDLNQVLSLKDNQLKVLLQKQQDVIR-- 3984

Query: 562  EELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLES 621
              L H  +  AE    +  L++     +SG +       ++ ++++   T+   I  L +
Sbjct: 3985 -NLEH-QKAAAEKRHRETRLEIQRRGEESGALAA-----EISQLKDRVATQEAEILTLRN 4037

Query: 622  QKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALV 681
            Q+     E  ++    D V  K A+ S LQ + +     +  L+EQI  L   KK+++  
Sbjct: 4038 QR-SATNEGRVIADLQDAVAVKAAECSHLQQNLLSQRTLTDGLQEQIQLLEKEKKQMSAE 4096

Query: 682  IENLKLDKEQLYGT-IKDLENDKEDIMNKLQNYIQENMDLTDKLE---------KMSAEK 731
             ++    +   +G  ++ +  ++E    +     ++ + L  KL          ++  E 
Sbjct: 4097 AKDKGKSQIDAFGREVEGMRRERETAEQRAAELAKDQLQLQQKLSESDTRSRNTRLQNES 4156

Query: 732  ISELLAKINHEEQSKIQT----QFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAV 787
            + + +A +  +    I+     +   D +++E    +  +E  L    S +  L +   V
Sbjct: 4157 LCKAMAALQDDRDQLIEDFKTLRNRYDEELRETRAALNKVERSLQDASSDLAMLAKQRDV 4216

Query: 788  M---------EDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLA 828
            +         +D    L +  DQL   L EK++  ++  ++      +LA
Sbjct: 4217 LLLKINALESKDSHAELNKLLDQLSKALSEKERDLTQAVLENSAHSRQLA 4266



 Score = 41.1 bits (92), Expect = 0.25
 Identities = 90/478 (18%), Positives = 199/478 (41%), Gaps = 54/478 (11%)

Query: 319  ANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNT 378
            A + EL +    L HL  Q+ ++++E E     M +  ++++S   +   LIS++    T
Sbjct: 3852 AAVKELRRLEAKLRHLQVQVDRSSQEREQTAVKMESFKESMASLQSERERLISQQRTLAT 3911

Query: 379  ASKMKSPWS--QLSSETLNQDTDKKINKNEIAKLE--MVIQSLNKDLVDKEYVISEKDTX 434
                    S  +L S+ + Q+  K +N+ +    E  M+   L +   D   V+S KD  
Sbjct: 3912 TGGKDGAASGERLVSKGMKQEIRKLLNQMDDLNSENAMLRAQLVRYREDLNQVLSLKDNQ 3971

Query: 435  XXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIK 494
                         ++ Q Q +  +++E     H     E  +   +++ Q + E +  + 
Sbjct: 3972 LK-----------VLLQKQQDVIRNLE-----HQKAAAEKRHRETRLEIQRRGEESGALA 4015

Query: 495  DVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSN 554
               +  L +++ + E +I  L ++  A N+  +       + +K         ++ S   
Sbjct: 4016 -AEISQLKDRVATQEAEILTLRNQRSATNEGRVIADLQDAVAVKA--------AECSHLQ 4066

Query: 555  KEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLK 614
            + ++        L +++  LE+EK  +     D    ++   D + +  E+E +   R  
Sbjct: 4067 QNLLSQRTLTDGLQEQIQLLEKEKKQMSAEAKDKGKSQI---DAFGR--EVEGMRRERET 4121

Query: 615  AISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSAS 674
            A    E +  +L ++   LQQK  E + +  + ++LQ++ +C             A++A 
Sbjct: 4122 A----EQRAAELAKDQLQLQQKLSESDTRSRN-TRLQNESLCK------------AMAAL 4164

Query: 675  KKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISE 734
            + +   +IE+ K  + +    +++       +   LQ+    ++ +  K   +   KI+ 
Sbjct: 4165 QDDRDQLIEDFKTLRNRYDEELRETRAALNKVERSLQD-ASSDLAMLAKQRDVLLLKINA 4223

Query: 735  LLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRR 792
            L +K +H E +K+  Q       +ERDL    +E+  S +  ++     S+  ++D R
Sbjct: 4224 LESKDSHAELNKLLDQLSKALSEKERDLTQAVLEN--SAHSRQLAAFSRSMGSLQDER 4279



 Score = 37.5 bits (83), Expect = 3.0
 Identities = 70/396 (17%), Positives = 163/396 (41%), Gaps = 22/396 (5%)

Query: 948  EKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQY 1007
            E+  + + +  +L AQL+E     + +  + ++  K   E  +  + K + Q+       
Sbjct: 31   EEMAERLTHTERLVAQLKEMIREKDAVLCSKDDQLKAEKEASEAKLSKLRLQNKAKVTSL 90

Query: 1008 INEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRV 1067
              ++ +L       D    +       A  +    +   + K+ +   +L    EE+   
Sbjct: 91   TIQLEELRRQQGGPDTPTRSKKGSSEGADQASRGKIVLLKKKVEELEQQLAQRVEELDNK 150

Query: 1068 SKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANN 1127
             K++   +   EE+  ++ E+D ++ E    K  + +++        S T  P      +
Sbjct: 151  RKEVESQRLRGEEMDAMLIERDRKLTE----KEAYIVHLQTALSGDQSFTPAPAQTSEAS 206

Query: 1128 VDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTEL---QECYTKIIQLETLNTE 1184
                           KV E EE     S+LQEQS  L   L   +E YT+   +   N +
Sbjct: 207  GAVQELQLLVQSLTRKVGESEE---RYSLLQEQSESLKELLVTEKEQYTRKEIMYKENIQ 263

Query: 1185 LTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSIS---SAVDQRGFEIAELW-- 1239
             T  D++ Q+  NQL  ++ Q++ +    L+  ++  + +     A+ Q+  E  E+   
Sbjct: 264  -TFKDIIIQKD-NQL-MEVSQMHEQELFKLAAKSDASADLEQLLKALKQKLHEKEEVLLG 320

Query: 1240 -KQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNK 1298
              Q +   + +    + +++V ++  + ++ ++  + Q +     ++   ++     +++
Sbjct: 321  KTQVINVLQGEVDGRDQQIKVSITEHKCRFPRVAQAKQKTEDASRSEAKFLKMKAWSKSR 380

Query: 1299 LQDKEEHLRNLQ--EKYADVIN-QIEILRSEIEDEK 1331
            ++  EE L+ +Q  + + D+I+ Q  I   E E E+
Sbjct: 381  IRQLEEELKKIQAGDAHLDLISLQSRITALEEEREE 416


>UniRef50_Q4T928 Cluster: Chromosome undetermined SCAF7646, whole
            genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
            Chromosome undetermined SCAF7646, whole genome shotgun
            sequence - Tetraodon nigroviridis (Green puffer)
          Length = 4089

 Score =  135 bits (327), Expect = 8e-30
 Identities = 269/1412 (19%), Positives = 567/1412 (40%), Gaps = 115/1412 (8%)

Query: 218  MTKMQENFIAMEAEWKDE---KQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKL 274
            +T +++  +A   + ++    +Q+L K  ES +  + + +E    L +   E   E   +
Sbjct: 930  ITSLKDQLVAAAQKLQESSQLQQQLSKKEESLEKELKASKEERNRLHSQAEEYRKEAQTV 989

Query: 275  AQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHL 334
            +Q+LE+               A+ +     + +   +E+  LE    T  ++K +L   L
Sbjct: 990  SQQLEEQKRSQGITRGEMKATAETAAALEAQLREAEKERQRLEAELKTRDSEKEKLSSDL 1049

Query: 335  NCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETL 394
              +    +  L+N L ++ +E + +    +  +  +  +  +      ++  S L S T 
Sbjct: 1050 QSKAENISN-LQNLLNSLKSEKQQLQEELEALTEELDLQKEKVRQLSQEAA-SALDSRTS 1107

Query: 395  NQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQL 454
             Q+  ++++  E A+L+  +  L + L +       +                +I  L+ 
Sbjct: 1108 YQNQAQQLSA-EAARLQQELDHLQRTLSELGCEAESRRDRVSVLEAQVSENAAVIKALRE 1166

Query: 455  EHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQ 514
            E ++     +L     ++E V  +A   EQL++ L +  +D  + DL  +  + ++++TQ
Sbjct: 1167 EKEEL----TLQKQELSSEHVQGLASTAEQLRRSLAE--RDEALADLQARADAQQKELTQ 1220

Query: 515  LNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSK-VSDSNKEIVRLTEELHHLSQKVAE 573
            L ++ + + K  +  K +   + + ++  +    + VS    +   L E+   + Q++  
Sbjct: 1221 LQEQ-ERSLKTQLAEKEHLGRENQSLKSEVGRQEEAVSKLQSDAKSLQEKHSQVCQQMEN 1279

Query: 574  LEEEKGNLQLHLVDYDSGRMIESDVYKKMIE-----------MENLAETRLKAISLLESQ 622
             EE   N++     +     + ++  K + E           +E+ AE R K +  L SQ
Sbjct: 1280 REETLRNVKRECQQHKEELNVRNETIKSLTEQMGLLRGAAGELESGAELRQKELIQLHSQ 1339

Query: 623  KFDLVQELHILQQKYDEVEDKLADISQLQSDQVCS-EIKSVHLEEQIDALSASKKELALV 681
               L ++   LQ      E +LA    LQS ++C  + +     EQ  +LSA    L   
Sbjct: 1340 IQALTEDKQQLQAARRTTEKELA----LQSQRLCDLQGQLKEALEQNSSLSAELGSLTQK 1395

Query: 682  IENLKLDKEQLYGTIKDLENDKEDIMNKL---QNYIQENMDLTDKLEKMSAE---KISEL 735
               L+ D  Q   ++ +L  D+  +  +L   +  I E+   TD+L K   E    + EL
Sbjct: 1396 NRALREDLAQKLESVSELAADRSALQQQLSGLEEQIAEDRQATDRLVKQKEELGSTVDEL 1455

Query: 736  LAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSL 795
               +    QS          +  +    ++  E  L      +  LE+ +A + D     
Sbjct: 1456 KKVLEESHQSNAAGLLEKTNECAKLSTALKEREGRLQSLSQDVVSLEKQVAELTDLMKEK 1515

Query: 796  ERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKN 855
            ER   +  S L+EKQ+   +       L    +VL     ++EK+ L  +   +      
Sbjct: 1516 ERTVLEQSSQLEEKQQELWQLGDSIRVLQGEESVL--RSGILEKEALVQQTAEQSRLHLE 1573

Query: 856  QILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQ 915
            Q+ L+++   Q+ + +++       E A      E E  K +     L S L ++T +++
Sbjct: 1574 QVALQKSLTAQLEV-ELECVRRERSEAALHLQQKEEELNKERQSGLSLSSQLSQVTQKNE 1632

Query: 916  TL---IVQKKKEIEDLEIEFNTQIESAIRDKKVLNEK---YEKNIEYVTQLEAQLQEYKN 969
             L   + Q+K EI DL        +     K  L E      ++ E V QL+A+      
Sbjct: 1633 LLARELEQRKAEITDLSDNVQALSQQRATFKSELRETGTALARSQEEVAQLKAECSRQ-- 1690

Query: 970  NIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALN 1029
              E L + ++E  ++   L  K    QQ  +            +L+ LL+QK +E ++L+
Sbjct: 1691 --EGLQVALQEKEQL---LRQKEALIQQMTASKA---------ELDQLLRQKTDEAVSLS 1736

Query: 1030 QKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQD 1089
             + ++ Q S   +    E    + +T   +++++ +   + L  S    E L+  ++++ 
Sbjct: 1737 TQTSDLQESIRRLRGQLERSALEVSTLQRSLQQKEESSLEGLSRSAAALETLRTDLQDKQ 1796

Query: 1090 DQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEE 1149
             +   LKE       ++ +    + + + E   DD   V               +Q+ + 
Sbjct: 1797 AECLSLKEQLSHLRESVTELSSALRAQSTEV--DDLKRVLGQKDAALSDQGRC-LQDVQS 1853

Query: 1150 FIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTE 1209
               E S+ + Q  + +TEL        QL +L+TE    D    +   + +S    L  +
Sbjct: 1854 RADEASLFKAQFME-STELVSQLQS--QLHSLSTECARLD----KSAGEAQSAFNNLKEK 1906

Query: 1210 NDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTE---HELRVQLSAFES 1266
                L  + + R  +S    QR  E++ L KQ L    +  Q+       LR ++SA   
Sbjct: 1907 YATSLEELQDARGQLS----QRMEEVSSLQKQ-LEDSASQHQRAAGAVETLRSEISAVGR 1961

Query: 1267 KYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSE 1326
            K E+  D   S ++E+       E + S Q K+      +  L+ ++  V  Q+ +L   
Sbjct: 1962 KLERAEDLNSSLSREKE------EALASHQAKVSLLTVEIEKLKSQHVQVAAQVNVLTEN 2015

Query: 1327 IEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXX 1386
            +E  ++A                  L +E Q+ +++ ++    + EE A  K+       
Sbjct: 2016 LEQREMALHAINSQHSSQARRTS-QLLSEMQTLQEVNQR----LQEEMASAKEEHQKLLA 2070

Query: 1387 XXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEK 1446
                   R+ +   + L    +LE +   + +++     T+ +   E ++++ ++   +K
Sbjct: 2071 ASSQENARLKEDAGRFLAEKEELEDRCHRLERQSSSLGETMARTTSERDDLQTKVSVQDK 2130

Query: 1447 RIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVA 1506
             +  L                +N    E + ++SE E + ++E       E    N+ V 
Sbjct: 2131 ELSQLK---------------DNVRKVEQILQDSEREWLLVLER------EKEEKNQLVE 2169

Query: 1507 ELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQ 1566
             L  ++E E++  +    AL+ Q+++  +L +++    + +R  S ++      AS ++ 
Sbjct: 2170 RLT-SVENEMSSKDVKVNALK-QDLD--SLQEKLALASSAIRQGSDQLGAKELEASASRL 2225

Query: 1567 GRDEQLDNTMNKELLDAVPRAELDLAMYMLHQ 1598
              ++ L +   KEL ++  +  L  A + LH+
Sbjct: 2226 QLEKLLASVQEKELDNSRLQQALGAAQHRLHR 2257



 Score =  129 bits (311), Expect = 7e-28
 Identities = 257/1382 (18%), Positives = 565/1382 (40%), Gaps = 93/1382 (6%)

Query: 212  EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271
            E  ++++ +  E    +     +E+ +L+ D++  +  I SL++   LLE  R EIS   
Sbjct: 751  ESLQREVDQTNEELDKLNTACLEERAQLIHDLQGCEREIDSLKDV--LLEKDR-EISALS 807

Query: 272  SKLAQELEQXXXXXXXXXXXXXXL--AKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIE 329
              +++  EQ              L   + ++  +  E   + E  S E  ++ +  + I+
Sbjct: 808  GHVSECTEQLSLLKHELKLKEQNLIQVENALSKAERELLLLRESRSSEQQSLED--RLIQ 865

Query: 330  LLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQL 389
            L + L     +  K  E++  ++  +  A+   + +    I    G     +M+S   +L
Sbjct: 866  LGDSLKDAQTELVKVREHR-DSLAAQVGALQEQAHQDEESILELRGE-VQKQMRSHGQRL 923

Query: 390  SSETLNQDTDKKINKNEIAKLE---MVIQSLNK--DLVDKEYVISEKDTXXXXXXXXXXG 444
            S    +  + K        KL+    + Q L+K  + ++KE   S+++            
Sbjct: 924  SEGEAHITSLKDQLVAAAQKLQESSQLQQQLSKKEESLEKELKASKEERNRLHSQAEEYR 983

Query: 445  KDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEK 504
            K+      QLE Q+  +G   I  G         A ++ QL++   +  +      L  +
Sbjct: 984  KEAQTVSQQLEEQKRSQG---ITRGEMKATAETAAALEAQLREAEKERQR------LEAE 1034

Query: 505  LKSAEEQITQLNDEIDAANKNMIKVKS---NHKLKLKQMQKTIDNFSKVSDSNKEIVRLT 561
            LK+ + +  +L+ ++ +  +N+  +++   + K + +Q+Q+ ++  ++  D  KE VR  
Sbjct: 1035 LKTRDSEKEKLSSDLQSKAENISNLQNLLNSLKSEKQQLQEELEALTEELDLQKEKVR-- 1092

Query: 562  EELHHLSQKVAELEEEKGNLQ--LHLVDYDSGRMIES--DVYKKMIEMENLAETRLKAIS 617
                 LSQ+ A   + + + Q     +  ++ R+ +    + + + E+   AE+R   +S
Sbjct: 1093 ----QLSQEAASALDSRTSYQNQAQQLSAEAARLQQELDHLQRTLSELGCEAESRRDRVS 1148

Query: 618  LLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKE 677
            +LE+Q   + +   +++   +E E+      +L S+ V     +    EQ+    A + E
Sbjct: 1149 VLEAQ---VSENAAVIKALREEKEELTLQKQELSSEHVQGLASTA---EQLRRSLAERDE 1202

Query: 678  LALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLA 737
             AL     + D +Q    +  L+  +  +  +L    +E++   ++  K    +  E ++
Sbjct: 1203 -ALADLQARADAQQK--ELTQLQEQERSLKTQLAE--KEHLGRENQSLKSEVGRQEEAVS 1257

Query: 738  KINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLER 797
            K+  + +S  +    +  +++ R+  + N++ E  ++K  +    E+I  + ++   L  
Sbjct: 1258 KLQSDAKSLQEKHSQVCQQMENREETLRNVKRECQQHKEELNVRNETIKSLTEQMGLLRG 1317

Query: 798  KADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQI 857
             A +L S  + +QK   +   Q   L      L    R  EK+L        +LQ + + 
Sbjct: 1318 AAGELESGAELRQKELIQLHSQIQALTEDKQQLQAARRTTEKELALQSQRLCDLQGQLKE 1377

Query: 858  LLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNL-KRITHEHQT 916
             LE+N +L   L  + Q   AL E   +   + SE    ++ L+   S L ++I  + Q 
Sbjct: 1378 ALEQNSSLSAELGSLTQKNRALREDLAQKLESVSELAADRSALQQQLSGLEEQIAEDRQA 1437

Query: 917  L--IVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENL 974
               +V++K+E+     E    +E + +         EK  E   +L   L+E +  +++L
Sbjct: 1438 TDRLVKQKEELGSTVDELKKVLEESHQSNAA--GLLEKTNE-CAKLSTALKEREGRLQSL 1494

Query: 975  NMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINN 1034
            + +V  L K   EL D   +K++T            + + ++ L++K +E+  L   I  
Sbjct: 1495 SQDVVSLEKQVAELTDLMKEKERT------------VLEQSSQLEEKQQELWQLGDSIRV 1542

Query: 1035 AQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKE 1094
             Q     + S    K A      E     +++V+ Q   + Q   EL+ + RE+ +    
Sbjct: 1543 LQGEESVLRSGILEKEALVQQTAEQSRLHLEQVALQKSLTAQLEVELECVRRERSEAALH 1602

Query: 1095 LKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQER 1154
            L++ +   E+N  +  G+ +SS +  ++     +             L     +   Q+R
Sbjct: 1603 LQQKE--EELNKERQSGLSLSSQLSQVTQKNELLARELEQRKAEITDLS-DNVQALSQQR 1659

Query: 1155 SVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLL 1214
            +  + +  +  T L     ++ QL+   +   G  V  QE+        EQL  + + L+
Sbjct: 1660 ATFKSELRETGTALARSQEEVAQLKAECSRQEGLQVALQEK--------EQLLRQKEALI 1711

Query: 1215 STVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQL--SAFE-SKYEQL 1271
              +   ++ +   + Q+  E        L+ + +D Q++   LR QL  SA E S  ++ 
Sbjct: 1712 QQMTASKAELDQLLRQKTDEAVS-----LSTQTSDLQESIRRLRGQLERSALEVSTLQRS 1766

Query: 1272 LDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEK 1331
            L   + S+ E  ++  +   + +L+  LQDK+    +L+E+ + +   +  L S +  + 
Sbjct: 1767 LQQKEESSLEGLSR--SAAALETLRTDLQDKQAECLSLKEQLSHLRESVTELSSALRAQS 1824

Query: 1332 VAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNIN-EENAQLKKSSXXXXXXXXX 1390
                                 R       +  E S+      E+ +L             
Sbjct: 1825 TEVDDLKRVLGQKDAALSDQGRCLQDVQSRADEASLFKAQFMESTELVSQLQSQLHSLST 1884

Query: 1391 XXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQL---VEYEKR 1447
               R++ +  +     + L+ K +   ++  +    L+QR +E  ++++QL       +R
Sbjct: 1885 ECARLDKSAGEAQSAFNNLKEKYATSLEELQDARGQLSQRMEEVSSLQKQLEDSASQHQR 1944

Query: 1448 IEDLTYEKESELAIL--RLKMHENANHYETMQKESEI-ERVKLIEELNVKITESVSLNKQ 1504
                     SE++ +  +L+  E+ N   + +KE  +      +  L V+I +  S + Q
Sbjct: 1945 AAGAVETLRSEISAVGRKLERAEDLNSSLSREKEEALASHQAKVSLLTVEIEKLKSQHVQ 2004

Query: 1505 VAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDT 1564
            VA     L E + +      A+ +Q         ++ +    ++  + ++Q+ ++ A + 
Sbjct: 2005 VAAQVNVLTENLEQREMALHAINSQHSSQARRTSQLLSEMQTLQEVNQRLQEEMASAKEE 2064

Query: 1565 KQ 1566
             Q
Sbjct: 2065 HQ 2066



 Score =  122 bits (295), Expect = 6e-26
 Identities = 278/1497 (18%), Positives = 599/1497 (40%), Gaps = 128/1497 (8%)

Query: 155  DNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDT 214
            +NA +V++   +  E   L  QE  +E  Q + +  +                    +  
Sbjct: 1156 ENA-AVIKALREEKEELTLQKQELSSEHVQGLASTAEQLRRSLAERDEALADLQARADAQ 1214

Query: 215  KQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKL 274
            ++++T++QE   +++ +   EK+ L ++ +S    +   EEA   L++    +  +HS++
Sbjct: 1215 QKELTQLQEQERSLKTQLA-EKEHLGRENQSLKSEVGRQEEAVSKLQSDAKSLQEKHSQV 1273

Query: 275  AQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSL-----EIANMTELTKKIE 329
             Q++E                 ++    +   K+  E+ G L     E+ +  EL +K E
Sbjct: 1274 CQQMENREETLRNVKRECQQHKEELNVRNETIKSLTEQMGLLRGAAGELESGAELRQK-E 1332

Query: 330  LLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISR-KSGRNTASKMKSPWSQ 388
            L++ L+ QI+   ++ +   A   T  K ++  S++   L  + K      S + +    
Sbjct: 1333 LIQ-LHSQIQALTEDKQQLQAARRTTEKELALQSQRLCDLQGQLKEALEQNSSLSAELGS 1391

Query: 389  LS--SETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKD 446
            L+  +  L +D  +K+    +++L     +L + L   E  I+E                
Sbjct: 1392 LTQKNRALREDLAQKL--ESVSELAADRSALQQQLSGLEEQIAEDRQATDRLVKQKEELG 1449

Query: 447  TLIAQLQ--LEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEK 504
            + + +L+  LE         L+      E  NE AK+   LK+      ++  ++ L + 
Sbjct: 1450 STVDELKKVLEESHQSNAAGLL------EKTNECAKLSTALKE------REGRLQSLSQD 1497

Query: 505  LKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRL-TEE 563
            + S E+Q+ +L D +    + +++  S  + K +++ +  D+  +V    + ++R    E
Sbjct: 1498 VVSLEKQVAELTDLMKEKERTVLEQSSQLEEKQQELWQLGDSI-RVLQGEESVLRSGILE 1556

Query: 564  LHHLSQKVAE---LEEEKGNLQLHL-----VDYDSGRMIESDVYKKMIEM-ENLAETRLK 614
               L Q+ AE   L  E+  LQ  L     V+ +  R   S+    + +  E L + R  
Sbjct: 1557 KEALVQQTAEQSRLHLEQVALQKSLTAQLEVELECVRRERSEAALHLQQKEEELNKERQS 1616

Query: 615  AISLLESQKFDLVQELHILQQKYDEVEDKLADIS-QLQS-DQVCSEIKSVHLEEQIDALS 672
             +S L SQ   + Q+  +L ++ ++ + ++ D+S  +Q+  Q  +  KS  L E   AL+
Sbjct: 1617 GLS-LSSQLSQVTQKNELLARELEQRKAEITDLSDNVQALSQQRATFKS-ELRETGTALA 1674

Query: 673  ASKKELALV------IENLKL---DKEQLY----GTIKDLENDKEDIMNKLQNYIQE--- 716
             S++E+A +       E L++   +KEQL       I+ +   K ++   L+    E   
Sbjct: 1675 RSQEEVAQLKAECSRQEGLQVALQEKEQLLRQKEALIQQMTASKAELDQLLRQKTDEAVS 1734

Query: 717  ----NMDLTDKLEKM------SAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIEN 766
                  DL + + ++      SA ++S L   +  +E+S ++      A ++     +++
Sbjct: 1735 LSTQTSDLQESIRRLRGQLERSALEVSTLQRSLQQKEESSLEGLSRSAAALETLRTDLQD 1794

Query: 767  IESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNR 826
             ++E    K ++  L ES+  +     +   + D L   L +K  A S+    +   +  
Sbjct: 1795 KQAECLSLKEQLSHLRESVTELSSALRAQSTEVDDLKRVLGQKDAALSD----QGRCLQD 1850

Query: 827  LAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRT 886
            +    D   + + Q +E      +LQ +   L  E   L  S  + Q  +N L EK   T
Sbjct: 1851 VQSRADEASLFKAQFMESTELVSQLQSQLHSLSTECARLDKSAGEAQSAFNNLKEK-YAT 1909

Query: 887  DLAESESTKYQTQLR-----DLESNLKRITHEHQT---LIVQKKKEIEDL--EIEFNTQI 936
             L E +  + Q   R      L+  L+    +HQ     +   + EI  +  ++E    +
Sbjct: 1910 SLEELQDARGQLSQRMEEVSSLQKQLEDSASQHQRAAGAVETLRSEISAVGRKLERAEDL 1969

Query: 937  ESAI-RDKKVLNEKYEKNIEYVT-QLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQ 994
             S++ R+K+     ++  +  +T ++E    ++      +N+  E L +  + L    + 
Sbjct: 1970 NSSLSREKEEALASHQAKVSLLTVEIEKLKSQHVQVAAQVNVLTENLEQREMAL--HAIN 2027

Query: 995  KQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFT 1054
             Q +     T Q ++E+  L  + ++  EE+ +  ++      +     +  +    +F 
Sbjct: 2028 SQHSSQARRTSQLLSEMQTLQEVNQRLQEEMASAKEEHQKLLAASSQENARLKEDAGRFL 2087

Query: 1055 TKLENMEEEMQRVSKQ-------LLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIP 1107
             + E +E+   R+ +Q       +  +    ++LQ  V  QD ++ +LK+     E  + 
Sbjct: 2088 AEKEELEDRCHRLERQSSSLGETMARTTSERDDLQTKVSVQDKELSQLKDNVRKVEQILQ 2147

Query: 1108 KTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTE 1167
             +E   +   +E   ++ N +               V +     Q+   LQE+ A  ++ 
Sbjct: 2148 DSEREWL-LVLEREKEEKNQLVERLTSVENEMSSKDV-KVNALKQDLDSLQEKLALASSA 2205

Query: 1168 LQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSA 1227
            +++      QL     E +     ++ Q+ +L + +++   +N  L   +   +  +   
Sbjct: 2206 IRQGSD---QLGAKELEAS----ASRLQLEKLLASVQEKELDNSRLQQALGAAQHRLHRL 2258

Query: 1228 VDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIV 1287
            + ++GF        H  Q   D       L   ++  E   +  +D+++S    E NK V
Sbjct: 2259 LQKKGFSAG---APH--QSPPDLSAAAACLHTMITQLEEGQQGQVDTLRS----EVNKSV 2309

Query: 1288 TMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDE----KVAFXXXXXXXXX 1343
                +   Q KL++ E      +++ A +  ++E+L+S++  +      A          
Sbjct: 2310 A--DLERTQEKLEEAERRSEQKEQEAAGLQTEVELLQSQLHAQVDITNQAAAKLERLSSQ 2367

Query: 1344 XXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVL 1403
                     R   Q  +Q Q+Q +++ +   AQ  +S                + +  V 
Sbjct: 2368 LQEKGDQISRMSVQLQQQQQQQQLVDKDAAVAQAMESQANQESVLAQLESLQQEHQRSVK 2427

Query: 1404 ELTHQLE--LKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAI 1461
                 LE   K  ++  +       L+++ +      Q L+E    +E L      + A 
Sbjct: 2428 RREQILEQKAKSEQLRSEKQLLESALSEKEERLSQAVQTLMEKSSVLEQLQASAAQKDAA 2487

Query: 1462 LRLKMHENANHYETMQKESEIE------RVKLIEELNVKITESVSLNKQVAELNKALEEE 1515
               +  +     + +QKE + E        +L +EL     E   L ++V     A +E 
Sbjct: 2488 FEQERKDWMQKLDQLQKELQKESTSPSASAELGKELAQVRLEKTKLERKVQAALLARKEA 2547

Query: 1516 VAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQL 1572
            + K  E + AL  +   + +  +++ +L+ + R++ S  Q  ++      Q RDE L
Sbjct: 2548 MKKAEEQERALTQELTGLRSFEEKVRDLEEL-RSTCSSDQDELAALRQLLQERDESL 2603



 Score =  107 bits (257), Expect = 2e-21
 Identities = 206/1022 (20%), Positives = 437/1022 (42%), Gaps = 98/1022 (9%)

Query: 628  QELHILQQKYDEVEDKLADISQLQS-DQVCSEIKSVHLEEQIDALSASKKEL--ALVIEN 684
            Q L + Q + ++++ +LA     QS D    ++    L +Q+  L+ +++ L  +LV + 
Sbjct: 608  QRLWVSQNELEKLQSQLASARHQQSRDAEKHQLLVTSLNQQLKGLTDTQESLESSLVEKE 667

Query: 685  LKLDKE----QLYGTIKDLENDKE-DIMNKLQNYIQENMDLTDKLEKMSA--EKISELLA 737
              L +     +L  ++++  + KE  +       +Q    L    +K S   ++ SEL A
Sbjct: 668  TALARTCQQLELVSSLQEALSLKELQLREASDKLLQAEHSLDSIWQKCSGSEKQCSELKA 727

Query: 738  KINHEEQSKIQTQFGI-DAKIQERDLYIENIESELSKYKSRICRL-----EESIAVMEDR 791
            ++     + +  + G+   K Q++++ IE+++ E+ +    + +L     EE   ++ D 
Sbjct: 728  EV-----ADLTQKLGVLKEKTQKQEVTIESLQREVDQTNEELDKLNTACLEERAQLIHDL 782

Query: 792  RYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKEL 851
            +   ER+ D L   L EK +  S  +    E   +L++L    ++ E+ L+++E+   + 
Sbjct: 783  Q-GCEREIDSLKDVLLEKDREISALSGHVSECTEQLSLLKHELKLKEQNLIQVENALSKA 841

Query: 852  QKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRIT 911
            +++  +L E   + Q SL D        ++ A +T+L +    +++  L      L+   
Sbjct: 842  ERELLLLRESRSSEQQSLEDRLIQLGDSLKDA-QTELVKVR--EHRDSLAAQVGALQEQA 898

Query: 912  HEHQTLIVQKKKEIEDLEIEFNTQI---ESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYK 968
            H+ +  I++ + E++        ++   E+ I   K       + ++  +QL+ QL + +
Sbjct: 899  HQDEESILELRGEVQKQMRSHGQRLSEGEAHITSLKDQLVAAAQKLQESSQLQQQLSKKE 958

Query: 969  NNIEN-LNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIA 1027
             ++E  L  + EE N+++ +  +++ ++ QT S    EQ  ++       +K   E   A
Sbjct: 959  ESLEKELKASKEERNRLHSQA-EEYRKEAQTVSQQLEEQKRSQ-GITRGEMKATAETAAA 1016

Query: 1028 LNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVRE 1087
            L  ++  A           E +  +   +L+  + E +++S  L    ++   LQ L+  
Sbjct: 1017 LEAQLREA-----------EKERQRLEAELKTRDSEKEKLSSDLQSKAENISNLQNLLNS 1065

Query: 1088 QDDQIKELKET--KLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQ 1145
               + ++L+E    LT E+++ K +       +  +S +A +              L   
Sbjct: 1066 LKSEKQQLQEELEALTEELDLQKEK-------VRQLSQEAASALDSRTSYQNQAQQLSA- 1117

Query: 1146 EEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQ 1205
            E     QE   LQ   ++L  E +    ++  LE   +E        +E+  +L  + ++
Sbjct: 1118 EAARLQQELDHLQRTLSELGCEAESRRDRVSVLEAQVSENAAVIKALREEKEELTLQKQE 1177

Query: 1206 LNTEN-DNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQRE--ADFQKTEHELRVQLS 1262
            L++E+   L ST  +LR S++    +R   +A+L  +  AQ++     Q+ E  L+ QL+
Sbjct: 1178 LSSEHVQGLASTAEQLRRSLA----ERDEALADLQARADAQQKELTQLQEQERSLKTQLA 1233

Query: 1263 AFE--SKYEQLLDSVQSSTQEETNKIVT-----MEQVTSLQNKLQDKEEHLRNLQEKYAD 1315
              E   +  Q L S     +E  +K+ +      E+ + +  +++++EE LRN++ +   
Sbjct: 1234 EKEHLGRENQSLKSEVGRQEEAVSKLQSDAKSLQEKHSQVCQQMENREETLRNVKRECQQ 1293

Query: 1316 VINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENA 1375
               ++ +    I+   +                  +LR +       Q Q++    E+  
Sbjct: 1294 HKEELNVRNETIKS--LTEQMGLLRGAAGELESGAELRQKELIQLHSQIQAL---TEDKQ 1348

Query: 1376 QLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQ---LELKDSEIYQKTHEYTITLTQRND 1432
            QL+ +             R+ D + ++ E   Q   L  +   + QK       L Q+ +
Sbjct: 1349 QLQAARRTTEKELALQSQRLCDLQGQLKEALEQNSSLSAELGSLTQKNRALREDLAQKLE 1408

Query: 1433 EFENV-------RQQLVEYEKRI-ED------LTYEKE---SELAILRLKMHEN--ANHY 1473
                +       +QQL   E++I ED      L  +KE   S +  L+  + E+  +N  
Sbjct: 1409 SVSELAADRSALQQQLSGLEEQIAEDRQATDRLVKQKEELGSTVDELKKVLEESHQSNAA 1468

Query: 1474 ETMQKESEIERVKL-IEELNVKIT----ESVSLNKQVAELNKALEEEVAKTNEMQTALEN 1528
              ++K +E  ++   ++E   ++     + VSL KQVAEL   ++E+     E  + LE 
Sbjct: 1469 GLLEKTNECAKLSTALKEREGRLQSLSQDVVSLEKQVAELTDLMKEKERTVLEQSSQLEE 1528

Query: 1529 QEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAE 1588
            ++ E+  L D I  LQ       S I +  +    T +     L+    ++ L A    E
Sbjct: 1529 KQQELWQLGDSIRVLQGEESVLRSGILEKEALVQQTAEQSRLHLEQVALQKSLTAQLEVE 1588

Query: 1589 LD 1590
            L+
Sbjct: 1589 LE 1590



 Score =  104 bits (249), Expect = 2e-20
 Identities = 223/1210 (18%), Positives = 493/1210 (40%), Gaps = 91/1210 (7%)

Query: 387  SQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKD 446
            SQL+S    Q  D + ++  +  L   ++ L       E  + EK+T             
Sbjct: 622  SQLASARHQQSRDAEKHQLLVTSLNQQLKGLTDTQESLESSLVEKETALARTCQQLELVS 681

Query: 447  TLIAQLQLEHQQHMEGPS-LIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKL 505
            +L   L L+  Q  E    L+    + + + +     E+   EL  E+ D+  K  + K 
Sbjct: 682  SLQEALSLKELQLREASDKLLQAEHSLDSIWQKCSGSEKQCSELKAEVADLTQKLGVLKE 741

Query: 506  KSAEEQIT---------QLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKV-SDSNK 555
            K+ ++++T         Q N+E+D  N   ++ ++     L+  ++ ID+   V  + ++
Sbjct: 742  KTQKQEVTIESLQREVDQTNEELDKLNTACLEERAQLIHDLQGCEREIDSLKDVLLEKDR 801

Query: 556  EIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKA 615
            EI  L+  +   +++++ L+ E    + +L+       +E+ + K   E+  L E+R   
Sbjct: 802  EISALSGHVSECTEQLSLLKHELKLKEQNLI------QVENALSKAERELLLLRESRSSE 855

Query: 616  ISLLESQKFDLVQELHILQQ---KYDEVEDKL-ADISQLQSDQVCSEIKSVHLEEQID-A 670
               LE +   L   L   Q    K  E  D L A +  LQ      E   + L  ++   
Sbjct: 856  QQSLEDRLIQLGDSLKDAQTELVKVREHRDSLAAQVGALQEQAHQDEESILELRGEVQKQ 915

Query: 671  LSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAE 730
            + +  + L+    ++   K+QL    + L+       ++LQ  + +  +  +K  K S E
Sbjct: 916  MRSHGQRLSEGEAHITSLKDQLVAAAQKLQES-----SQLQQQLSKKEESLEKELKASKE 970

Query: 731  KISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMED 790
            + + L ++   E + + QT   +  +++E+         E+         LE  +   E 
Sbjct: 971  ERNRLHSQA-EEYRKEAQT---VSQQLEEQKRSQGITRGEMKATAETAAALEAQLREAEK 1026

Query: 791  RRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLL-EIEHENK 849
             R  LE    +L +   EK+K  S+   + + + N L  L++  +  ++QL  E+E   +
Sbjct: 1027 ERQRLEA---ELKTRDSEKEKLSSDLQSKAENISN-LQNLLNSLKSEKQQLQEELEALTE 1082

Query: 850  ELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKR 909
            EL  + + + + +Q    +L D +  Y       N+     +E+ + Q +L  L+  L  
Sbjct: 1083 ELDLQKEKVRQLSQEAASAL-DSRTSYQ------NQAQQLSAEAARLQQELDHLQRTLSE 1135

Query: 910  ITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKK--VLNEKYEKNIEYVTQLEAQLQEY 967
            +  E ++   + +  + + ++  N  +  A+R++K  +  +K E + E+V  L +  ++ 
Sbjct: 1136 LGCEAESR--RDRVSVLEAQVSENAAVIKALREEKEELTLQKQELSSEHVQGLASTAEQL 1193

Query: 968  KNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIA 1027
            + ++   +  + +L +   +   K + + Q Q      Q + E   L    +    E+  
Sbjct: 1194 RRSLAERDEALADL-QARADAQQKELTQLQEQERSLKTQ-LAEKEHLGRENQSLKSEVGR 1251

Query: 1028 LNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQI---L 1084
              + ++  Q    S+    + K +Q   ++EN EE ++ V +   + +QH EEL +    
Sbjct: 1252 QEEAVSKLQSDAKSL----QEKHSQVCQQMENREETLRNVKR---ECQQHKEELNVRNET 1304

Query: 1085 VREQDDQIKELKET--KLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXL 1142
            ++   +Q+  L+    +L     + + E + + S I+ +++D   +             L
Sbjct: 1305 IKSLTEQMGLLRGAAGELESGAELRQKELIQLHSQIQALTEDKQQLQ-AARRTTEKELAL 1363

Query: 1143 KVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQL-ETL--NTELTGHDVVNQEQINQL 1199
            + Q   +   +     EQ++ L+ EL     K   L E L    E       ++  + Q 
Sbjct: 1364 QSQRLCDLQGQLKEALEQNSSLSAELGSLTQKNRALREDLAQKLESVSELAADRSALQQQ 1423

Query: 1200 KSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEH--EL 1257
             S LE+   E+      + + +  + S VD+    + E    H +      +KT    +L
Sbjct: 1424 LSGLEEQIAEDRQATDRLVKQKEELGSTVDELKKVLEE---SHQSNAAGLLEKTNECAKL 1480

Query: 1258 RVQLSAFESKYEQLLDSVQSSTQE--ETNKIVTMEQVTSLQ--NKLQDKEEHLRNLQEKY 1313
               L   E + + L   V S  ++  E   ++  ++ T L+  ++L++K++ L  L +  
Sbjct: 1481 STALKEREGRLQSLSQDVVSLEKQVAELTDLMKEKERTVLEQSSQLEEKQQELWQLGDSI 1540

Query: 1314 ADVINQIEILRSEIEDEKVAFXXXXXXX------XXXXXXXXXDLRTENQSYKQMQEQSI 1367
              +  +  +LRS I +++                          L  E +  ++ + ++ 
Sbjct: 1541 RVLQGEESVLRSGILEKEALVQQTAEQSRLHLEQVALQKSLTAQLEVELECVRRERSEAA 1600

Query: 1368 LNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITL 1427
            L++ ++  +L K              +++    K   L  +LE + +EI   +       
Sbjct: 1601 LHLQQKEEELNKE----RQSGLSLSSQLSQVTQKNELLARELEQRKAEITDLSDNVQALS 1656

Query: 1428 TQR---NDEFENVRQQLVEYEKRIEDLTYE--KESELAILRLKMHENANHYETMQKESEI 1482
             QR     E       L   ++ +  L  E  ++  L +   +  +     E + ++   
Sbjct: 1657 QQRATFKSELRETGTALARSQEEVAQLKAECSRQEGLQVALQEKEQLLRQKEALIQQMTA 1716

Query: 1483 ERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITN 1542
             + +L + L  K  E+VSL+ Q ++L +++     +    ++ALE   ++      E ++
Sbjct: 1717 SKAELDQLLRQKTDEAVSLSTQTSDLQESIRR--LRGQLERSALEVSTLQRSLQQKEESS 1774

Query: 1543 LQNMVRASSS 1552
            L+ + R++++
Sbjct: 1775 LEGLSRSAAA 1784



 Score =  100 bits (239), Expect = 4e-19
 Identities = 242/1257 (19%), Positives = 522/1257 (41%), Gaps = 126/1257 (10%)

Query: 147  LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXX 206
            L   I E   A   L  + + + +T+ +L++ + E  Q   A     T            
Sbjct: 1427 LEEQIAEDRQATDRLVKQKEELGSTVDELKKVLEESHQSNAAGLLEKTNECAKLSTALKE 1486

Query: 207  XXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKD---IESKDVRISSLEEANKLLEAA 263
                 +   Q +  +++    +    K++++ +L+    +E K   +  L ++ ++L+  
Sbjct: 1487 REGRLQSLSQDVVSLEKQVAELTDLMKEKERTVLEQSSQLEEKQQELWQLGDSIRVLQGE 1546

Query: 264  RFEIS---LEHSKLAQEL-EQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIA 319
               +    LE   L Q+  EQ               A+  +E  C  +   E    L+  
Sbjct: 1547 ESVLRSGILEKEALVQQTAEQSRLHLEQVALQKSLTAQLEVELECVRRERSEAALHLQ-Q 1605

Query: 320  NMTELTKKIELLEHLNCQIRQTN-------KELENKLATMGTESKAVSSPSKKGSPLISR 372
               EL K+ +    L+ Q+ Q         +ELE + A +   S  V + S++ +   S 
Sbjct: 1606 KEEELNKERQSGLSLSSQLSQVTQKNELLARELEQRKAEITDLSDNVQALSQQRATFKSE 1665

Query: 373  KSGRNTA-SKMKSPWSQLSSETLNQD-TDKKINKNE--IAKLEMVIQSLNKDLVDKEYVI 428
                 TA ++ +   +QL +E   Q+     + + E  + + E +IQ +     + + ++
Sbjct: 1666 LRETGTALARSQEEVAQLKAECSRQEGLQVALQEKEQLLRQKEALIQQMTASKAELDQLL 1725

Query: 429  SEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVG------TNTEDVNEIAKVQ 482
             +K                 I +L+ + ++     S +         ++ E ++  A   
Sbjct: 1726 RQKTDEAVSLSTQTSDLQESIRRLRGQLERSALEVSTLQRSLQQKEESSLEGLSRSAAAL 1785

Query: 483  EQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVK----------SN 532
            E L+ +L D  K      L E+L    E +T+L+  + A +  +  +K          S+
Sbjct: 1786 ETLRTDLQD--KQAECLSLKEQLSHLRESVTELSSALRAQSTEVDDLKRVLGQKDAALSD 1843

Query: 533  HKLKLKQMQKTIDNFS----KVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDY 588
                L+ +Q   D  S    +  +S + + +L  +LH LS + A L++  G  Q     +
Sbjct: 1844 QGRCLQDVQSRADEASLFKAQFMESTELVSQLQSQLHSLSTECARLDKSAGEAQSA---F 1900

Query: 589  DSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADIS 648
            ++ +   +   +++ +       R++ +S L+ Q  D   + H  Q+    VE   ++IS
Sbjct: 1901 NNLKEKYATSLEELQDARGQLSQRMEEVSSLQKQLEDSASQ-H--QRAAGAVETLRSEIS 1957

Query: 649  QL-QSDQVCSEIKSVHLEEQIDALSASKKELALV---IENLKLDKEQLYGTIKDLENDKE 704
             + +  +   ++ S    E+ +AL++ + +++L+   IE LK    Q+   +  L  + E
Sbjct: 1958 AVGRKLERAEDLNSSLSREKEEALASHQAKVSLLTVEIEKLKSQHVQVAAQVNVLTENLE 2017

Query: 705  DIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYI 764
                 L     ++     +  ++ +E   + L ++N   Q ++ +     AK + + L  
Sbjct: 2018 QREMALHAINSQHSSQARRTSQLLSEM--QTLQEVNQRLQEEMAS-----AKEEHQKLLA 2070

Query: 765  ENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYL----QEKQKAYSEYTIQE 820
             + + E ++ K    R       +EDR + LER++  LG  +     E+    ++ ++Q+
Sbjct: 2071 ASSQ-ENARLKEDAGRFLAEKEELEDRCHRLERQSSSLGETMARTTSERDDLQTKVSVQD 2129

Query: 821  DELVNRLAVLMDHDRVVEKQLLEIEHE-----NKELQKKNQILLEENQNLQISLSDMQQH 875
             E    L+ L D+ R VE+ L + E E      +E ++KNQ L+E   +++  +S     
Sbjct: 2130 KE----LSQLKDNVRKVEQILQDSEREWLLVLEREKEEKNQ-LVERLTSVENEMSSKDVK 2184

Query: 876  YNALVEKAN----RTDLAESESTKYQTQL--RDLESNLKRITHEHQTLIVQKKKEIEDLE 929
             NAL +  +    +  LA S   +   QL  ++LE++  R+  E     VQ +KE+++  
Sbjct: 2185 VNALKQDLDSLQEKLALASSAIRQGSDQLGAKELEASASRLQLEKLLASVQ-EKELDNSR 2243

Query: 930  IEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELI 989
            ++    + +A      L +K   +     Q    L      +  +   +EE  +  ++ +
Sbjct: 2244 LQ--QALGAAQHRLHRLLQKKGFSAGAPHQSPPDLSAAAACLHTMITQLEEGQQGQVDTL 2301

Query: 990  DKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQV---SYMSMVSDY 1046
               V K      + T++ + E  + +   +QK++E   L  ++   Q    + + + +  
Sbjct: 2302 RSEVNK-SVADLERTQEKLEEAERRS---EQKEQEAAGLQTEVELLQSQLHAQVDITNQA 2357

Query: 1047 ESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNI 1106
             +KL + +++L+   +++ R+S QL    Q  ++ Q LV ++D  + +  E++   E  +
Sbjct: 2358 AAKLERLSSQLQEKGDQISRMSVQL----QQQQQQQQLV-DKDAAVAQAMESQANQESVL 2412

Query: 1107 PKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNT 1166
             + E +          +   +V              +++ E++ ++  S L E+  +L+ 
Sbjct: 2413 AQLESL--------QQEHQRSVKRREQILEQKAKSEQLRSEKQLLE--SALSEKEERLSQ 2462

Query: 1167 ELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTE---NDNLLSTVAELRSS 1223
             +Q    K   LE L       D   +++      KL+QL  E        S  AEL   
Sbjct: 2463 AVQTLMEKSSVLEQLQASAAQKDAAFEQERKDWMQKLDQLQKELQKESTSPSASAELGKE 2522

Query: 1224 ISSAVDQRGFEIAELWKQHLAQREA--DFQKTEHELRVQLSAFESKYEQL--LDSVQSST 1279
            ++    ++     ++    LA++EA    ++ E  L  +L+   S  E++  L+ ++S+ 
Sbjct: 2523 LAQVRLEKTKLERKVQAALLARKEAMKKAEEQERALTQELTGLRSFEEKVRDLEELRSTC 2582

Query: 1280 QEETNKIVTMEQVTSLQNKLQDKEEHLRNL-----QEKYADVINQIEILRSEIEDEK 1331
              + +++  + Q+      LQ+++E LR+L     Q + A + N    L+ E+ED K
Sbjct: 2583 SSDQDELAALRQL------LQERDESLRDLKLSLDQHQSASLAN----LKEELEDLK 2629



 Score =   99 bits (238), Expect = 5e-19
 Identities = 197/1113 (17%), Positives = 449/1113 (40%), Gaps = 76/1113 (6%)

Query: 445  KDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEK 504
            K+ L   ++L+ QQ     S  H        +E A++Q   +   + + K   +   ++ 
Sbjct: 2808 KEELRPAVELQLQQQ----SRAHHAWMERAKSEAAELQRSQQHPQDGQSKMAALTRKLQA 2863

Query: 505  LKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKV-----SDSNKEIVR 559
               + +++ + N  +    K + + +   +++L  ++  ++   +      + ++K+ V 
Sbjct: 2864 ALLSRKELMKENSALKQDAKRLAEKEHAKEVELSALEAALEEVKREKRELETSASKDKVE 2923

Query: 560  LTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLL 619
            L  E+  L  +   L    G+L+L + +    +   S       ++E L +++ + +S  
Sbjct: 2924 LRGEMDRLLSENHSLSAACGSLKLTIENMGQQKEAFS------CQLEALKDSQAEELSRW 2977

Query: 620  ESQKFDLVQELHILQQKYDEVE---DKLADISQLQSDQVCSEIKSVH-LEEQIDALSASK 675
             SQ  +L Q+   L + Y       D +  + +         ++  H LE + DAL    
Sbjct: 2978 RSQHAELKQQHESLLRSYQSTGAQMDAMRHVLEATERDALEAVRKSHRLETERDALEKQA 3037

Query: 676  KELA----LVIENLKLDKEQLYGTIKDLENDKEDIMNKL----QNYIQENMDLTDKLEKM 727
            +EL      + E +     +   T+++LE +K++   +L    +N+ +E  +L    +++
Sbjct: 3038 RELEGEHDRIKERMHTFSREKQWTVEELEREKQNSRRRLRELEENHSREASELGHANQQL 3097

Query: 728  SAEKISELLAKINH--EEQSKIQTQFGIDAK-IQERDLYIENIESELSKYKSRI-CRLEE 783
             AE I  L A      E+ S++Q++    A+ +QE    +E   +E  + +S +  +LEE
Sbjct: 3098 EAE-ICRLRASAEELGEKLSELQSENKRMAQELQESSCTLEERSAESERSRSSLQLQLEE 3156

Query: 784  SIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLE 843
            ++  ME +   L  + +      +EKQ         + EL  + A++ +   VV +   E
Sbjct: 3157 ALGRMETQTTELGAQVELNNLLQKEKQNLSQHMEAMQTELGKKEALIQELQEVVSRHSQE 3216

Query: 844  IEHENKE---LQKKNQILLEENQNLQISLSDM--QQHY--NALVEKANRTDLAESESTKY 896
                N++   L+    +L EE +N+Q +   +  ++ Y    L++ + + D         
Sbjct: 3217 TVSLNEKVRILEDDKSLLQEELENVQETSDKVKNEKEYLETVLLQNSEKVDELTESVAVL 3276

Query: 897  QTQLRDLESNLKRITHEHQTLIVQKKKE----IEDLEIEFNTQIESAIRDKKVLNEKYEK 952
            Q+Q  +L S L   +H +  +  +K++E    + +LE +    ++   +  K +N++ ++
Sbjct: 3277 QSQNLELNSQLAASSHTNHRVRQEKEEEQLRLVRELEEKLRA-VQRGSQGSKTINKELQE 3335

Query: 953  NIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEIN 1012
             ++   Q   QLQ+     + + + +E  +K +   +++ +Q++  +S +       + +
Sbjct: 3336 LLKEKHQEINQLQQNCIRYQEVILQLESSSKSSQAAVEQ-LQRELEKSSEQLSAVRQKCS 3394

Query: 1013 KLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLL 1072
            +  A L ++   +    QK   A+        D            E+   E  +  K+ +
Sbjct: 3395 RAEAELSEQRNLLQQAQQKRPGAESQRDPTALDLSHPSRSSEGHRESQPAE--KADKEAV 3452

Query: 1073 DSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXX 1132
              +Q   +L +   ++  +++ELK+   + ++ +   EG + SS  +  +  A       
Sbjct: 3453 -LQQQMAQLVLSKDQESKKVQELKQQLDSGDVELKALEGALRSSEAKLSALSARPAGPEA 3511

Query: 1133 XXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVN 1192
                         E+ + ++  SV++     +  + +E     +    L   +  + V  
Sbjct: 3512 SSLWTQVHQQAGSEDHQLLEPGSVIKRSLQNIRVKEKEMDELRLTHLKLQRTIDQYSVAA 3571

Query: 1193 QEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQK 1252
              Q  QL   L   N +       +    + +S+ VD+   E  +L ++ L+ RE    +
Sbjct: 3572 AAQQRQL-FVLSANNADVCERAELMGAQVTELSAQVDRLEKE-KDLLRRQLSDREDAVCQ 3629

Query: 1253 TEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQE- 1311
            T+ +L+      +++  + L +     +     + T+         LQ K+  + +L   
Sbjct: 3630 TQLQLQ------QAQKRRCLQAASERLEGLAAHLKTL---------LQSKDAEISSLLSC 3674

Query: 1312 KYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNIN 1371
            K A +   ++ L++    +  A+                 LR      + +Q Q   +  
Sbjct: 3675 KDAQMSGYLQQLQANGRSQAAAYEARLAALGHQREAAAGQLRGLQAKVRHLQVQVDTSSQ 3734

Query: 1372 EENAQLKKSSXXXXXXXXXXXXRVN-DAEAKVLELTHQLELK--DSE------IYQKTHE 1422
            E      K              R    +  + LE  ++L L+  D E      + Q+  +
Sbjct: 3735 ESQQAAAKMDAFRKSMAALQSERERLVSRCRTLETENRLGLRGPDGEGGASKGLKQEIRK 3794

Query: 1423 YTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEI 1482
                +   N E   +R QLV Y + +  +   K+ +L +L  K  +   + E  +  +E 
Sbjct: 3795 LLNQMDDLNSENAMLRAQLVRYREDLNQVLSLKDDQLKLLLQKQQDAIRNLEQQKAAAEE 3854

Query: 1483 ERVKLIEELNVKITESVSLNKQVAELNKALEEE 1515
            ++ +   ++  K  ES +L  Q+A   +A EEE
Sbjct: 3855 QQREARLQVQQKEEESEALRAQLAR-ERAQEEE 3886



 Score = 92.3 bits (219), Expect = 1e-16
 Identities = 267/1449 (18%), Positives = 563/1449 (38%), Gaps = 114/1449 (7%)

Query: 147  LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXX 206
            ++ T  E+D+    LQ K+ + +  +  L++ + + +QI++   +               
Sbjct: 2111 MARTTSERDD----LQTKVSVQDKELSQLKDNVRKVEQILQDSEREWLLVLEREKEEKNQ 2166

Query: 207  XXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFE 266
                    + +M+       A++ +    +++L   + S  +R  S +   K LEA+   
Sbjct: 2167 LVERLTSVENEMSSKDVKVNALKQDLDSLQEKLA--LASSAIRQGSDQLGAKELEASASR 2224

Query: 267  ISLEHSKLA-QELE-QXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTEL 324
            + LE    + QE E                L +   +         +    L  A     
Sbjct: 2225 LQLEKLLASVQEKELDNSRLQQALGAAQHRLHRLLQKKGFSAGAPHQSPPDLSAAAACLH 2284

Query: 325  TKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKS 384
            T   +L E    Q+     E+   +A +    + +    ++        +G  T  ++  
Sbjct: 2285 TMITQLEEGQQGQVDTLRSEVNKSVADLERTQEKLEEAERRSEQKEQEAAGLQTEVELLQ 2344

Query: 385  PWSQLSSETLNQDTDK--KINKNEIAKLEMVIQ-SLNKDLVDKEYVISEKDTXXXXXXXX 441
                   +  NQ   K  +++     K + + + S+      ++  + +KD         
Sbjct: 2345 SQLHAQVDITNQAAAKLERLSSQLQEKGDQISRMSVQLQQQQQQQQLVDKDAAVAQAMES 2404

Query: 442  XXGKDTLIAQLQLEHQQHMEG----PSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVN 497
               +++++AQL+   Q+H         ++     +E +    ++ E    E  + +    
Sbjct: 2405 QANQESVLAQLESLQQEHQRSVKRREQILEQKAKSEQLRSEKQLLESALSEKEERLSQA- 2463

Query: 498  VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKL-KQMQKTIDNFSKVSDSNKE 556
            V+ L+EK  S  EQ+     + DAA +   K       +L K++QK   + S  ++  KE
Sbjct: 2464 VQTLMEK-SSVLEQLQASAAQKDAAFEQERKDWMQKLDQLQKELQKESTSPSASAELGKE 2522

Query: 557  IVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIE-MENLAETRLKA 615
            + ++  E   L +KV      +        + +     E    +   E + +L E R   
Sbjct: 2523 LAQVRLEKTKLERKVQAALLARKEAMKKAEEQERALTQELTGLRSFEEKVRDLEELR--- 2579

Query: 616  ISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVH-LEEQIDALS-- 672
             S   S + +L     +LQ++ + + D    + Q QS  + +  + +  L+ Q   LS  
Sbjct: 2580 -STCSSDQDELAALRQLLQERDESLRDLKLSLDQHQSASLANLKEELEDLKSQNGHLSEE 2638

Query: 673  -ASKKELALVIENLK--LDKEQLYGTIKDLEN------DKEDIMNKLQNYIQENMDLTDK 723
             ASK+E  +V E     LD + L   ++ LE       DK + + K Q  ++   +LT +
Sbjct: 2639 LASKEEALMVGEQRAQALDSK-LLTVVEHLETAQAELRDKSEQVEKHQEALRAQ-ELTAE 2696

Query: 724  LEKMSAEKISELLAKINHEEQSKI-QTQFGIDAKIQERD---LYIENIESELSKYKSRIC 779
             EK + E   +LL     EE+ +  + Q  +D   +E+      I  ++ EL    +++ 
Sbjct: 2697 QEKGALESQLDLLTSALEEERRRCAEQQSRLDLSEREQAGAATLIRQLKDELGAGGTKLA 2756

Query: 780  RLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEK 839
            + ++    ++          DQ G+    +Q+      +QED    + A LM   ++ EK
Sbjct: 2757 QFDK----VKTCDVCKSGPDDQQGACFSCQQRE----KLQEDLKERQEAFLMSRAQLSEK 2808

Query: 840  QLLE--IEHENKELQKKNQILLEENQNLQISLSDMQQHYN-------ALVEKANRTDLAE 890
            + L   +E + ++  + +   +E  ++    L   QQH         AL  K     L+ 
Sbjct: 2809 EELRPAVELQLQQQSRAHHAWMERAKSEAAELQRSQQHPQDGQSKMAALTRKLQAALLSR 2868

Query: 891  SESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKY 950
             E  K  + L+     L    H  +  +   +  +E+++ E      SA +DK  L  + 
Sbjct: 2869 KELMKENSALKQDAKRLAEKEHAKEVELSALEAALEEVKREKRELETSASKDKVELRGEM 2928

Query: 951  EKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINE 1010
            ++ +     L A     K  IEN+    E  +   LE +            D   + ++ 
Sbjct: 2929 DRLLSENHSLSAACGSLKLTIENMGQQKEAFS-CQLEAL-----------KDSQAEELSR 2976

Query: 1011 INKLNALLKQKDEEIIALNQKINNAQVSYMSMVSD-YESKLAQFTTKLENMEEEMQRVSK 1069
                +A LKQ+ E ++   Q    AQ+  M  V +  E    +   K   +E E   + K
Sbjct: 2977 WRSQHAELKQQHESLLRSYQS-TGAQMDAMRHVLEATERDALEAVRKSHRLETERDALEK 3035

Query: 1070 QLLDSK-QHN---EELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDA 1125
            Q  + + +H+   E +    RE+   ++EL+  K      + + E        E  S +A
Sbjct: 3036 QARELEGEHDRIKERMHTFSREKQWTVEELEREKQNSRRRLRELE--------ENHSREA 3087

Query: 1126 NNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQE--CYTKIIQLETLNT 1183
            + +             L+    EE  ++ S LQ ++ ++  ELQE  C  +    E+  +
Sbjct: 3088 SELGHANQQLEAEICRLRA-SAEELGEKLSELQSENKRMAQELQESSCTLEERSAESERS 3146

Query: 1184 ELTGHDVVNQEQINQLKSKLEQL--NTENDNLL----STVAELRSSISSAVDQRGFEIAE 1237
              +   +  +E + +++++  +L    E +NLL      +++   ++ + + ++   I E
Sbjct: 3147 R-SSLQLQLEEALGRMETQTTELGAQVELNNLLQKEKQNLSQHMEAMQTELGKKEALIQE 3205

Query: 1238 LWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQN 1297
            L ++ +++   +      ++R+ L   +S  ++ L++VQ ++ +  N+   +E V  LQN
Sbjct: 3206 L-QEVVSRHSQETVSLNEKVRI-LEDDKSLLQEELENVQETSDKVKNEKEYLETVL-LQN 3262

Query: 1298 --KLQDKEEHLRNLQEKYADVINQIEI-------LRSEIEDEKVAFXXXXXXXXXXXXXX 1348
              K+ +  E +  LQ +  ++ +Q+         +R E E+E++                
Sbjct: 3263 SEKVDELTESVAVLQSQNLELNSQLAASSHTNHRVRQEKEEEQLRLVRELEEKLRAVQRG 3322

Query: 1349 XXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQ 1408
                +T N+  +++ ++    IN    QL+++                 ++A V +L  +
Sbjct: 3323 SQGSKTINKELQELLKEKHQEIN----QLQQNCIRYQEVILQLESSSKSSQAAVEQLQRE 3378

Query: 1409 LELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHE 1468
            LE K SE      +          E  N+ QQ  +     E    +++     L      
Sbjct: 3379 LE-KSSEQLSAVRQKCSRAEAELSEQRNLLQQAQQKRPGAES---QRDPTALDLSHPSRS 3434

Query: 1469 NANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALEN 1528
            +  H E+   E   +   L +++   +      +K+V EL + L+    +   ++ AL +
Sbjct: 3435 SEGHRESQPAEKADKEAVLQQQMAQLVLSKDQESKKVQELKQQLDSGDVELKALEGALRS 3494

Query: 1529 QEIEIVTLN 1537
             E ++  L+
Sbjct: 3495 SEAKLSALS 3503



 Score = 83.8 bits (198), Expect = 4e-14
 Identities = 258/1477 (17%), Positives = 585/1477 (39%), Gaps = 114/1477 (7%)

Query: 148  SNTIKEKDNALSVLQVKMKIMETTILDLQEK-------INEKDQIIEAKNKATTXXXXXX 200
            S+  +EK+ AL+  Q K+ ++   I  L+ +       +N   + +E +  A        
Sbjct: 1971 SSLSREKEEALASHQAKVSLLTVEIEKLKSQHVQVAAQVNVLTENLEQREMALHAINSQH 2030

Query: 201  XXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLL 260
                        +  Q + ++ +      A  K+E Q+LL     ++ R+   E+A + L
Sbjct: 2031 SSQARRTSQLLSEM-QTLQEVNQRLQEEMASAKEEHQKLLAASSQENARLK--EDAGRFL 2087

Query: 261  -EAARFE-----ISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQ--SIEPSCEEKTEIEE 312
             E    E     +  + S L + + +                K+   ++ +  +  +I +
Sbjct: 2088 AEKEELEDRCHRLERQSSSLGETMARTTSERDDLQTKVSVQDKELSQLKDNVRKVEQILQ 2147

Query: 313  KGSLEIANMTELTK--KIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLI 370
                E   + E  K  K +L+E L   +       + K+  +  +  ++       S  I
Sbjct: 2148 DSEREWLLVLEREKEEKNQLVERLT-SVENEMSSKDVKVNALKQDLDSLQEKLALASSAI 2206

Query: 371  SRKSGRNTASKMKSPWSQLSSETLNQDT-DKKINKNEIAK-LEMVIQSLNKDLVDKEYVI 428
             + S +  A ++++  S+L  E L     +K+++ + + + L      L++ L  K +  
Sbjct: 2207 RQGSDQLGAKELEASASRLQLEKLLASVQEKELDNSRLQQALGAAQHRLHRLLQKKGFSA 2266

Query: 429  SEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHME------GPSLIHVGTNTEDVNEIAKVQ 482
                              T+I QL+   Q  ++        S+  +    E + E  +  
Sbjct: 2267 GAPHQSPPDLSAAAACLHTMITQLEEGQQGQVDTLRSEVNKSVADLERTQEKLEEAERRS 2326

Query: 483  EQLKQE---LNDEIK--DVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKL 537
            EQ +QE   L  E++     +   ++    A  ++ +L+ ++      + ++ S    + 
Sbjct: 2327 EQKEQEAAGLQTEVELLQSQLHAQVDITNQAAAKLERLSSQLQEKGDQISRM-SVQLQQQ 2385

Query: 538  KQMQKTIDNFSKV-----SDSNKEIV----RLTEELHHLSQKVAE--LEEEKGNLQLHLV 586
            +Q Q+ +D  + V     S +N+E V       ++ H  S K  E  LE++  + QL   
Sbjct: 2386 QQQQQLVDKDAAVAQAMESQANQESVLAQLESLQQEHQRSVKRREQILEQKAKSEQLR-- 2443

Query: 587  DYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLAD 646
                 +++ES + +K   +    +T ++  S+LE  +    Q+    +Q+  +   KL  
Sbjct: 2444 --SEKQLLESALSEKEERLSQAVQTLMEKSSVLEQLQASAAQKDAAFEQERKDWMQKLDQ 2501

Query: 647  ISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDI 706
            + +    +  S   S  L +++  +   K +L   ++   L +++     ++ E      
Sbjct: 2502 LQKELQKESTSPSASAELGKELAQVRLEKTKLERKVQAALLARKEAMKKAEEQERALTQE 2561

Query: 707  MNKLQNYIQENMDLTDKLEKMSAEK--ISELLAKINHEEQSKIQTQFGIDAKIQERDLYI 764
            +  L+++ ++  DL +     S+++  ++ L   +   ++S    +  +D   Q +   +
Sbjct: 2562 LTGLRSFEEKVRDLEELRSTCSSDQDELAALRQLLQERDESLRDLKLSLD---QHQSASL 2618

Query: 765  ENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELV 824
             N++ EL   KS+   L E +A  E+     E++A  L S L          T+ E  L 
Sbjct: 2619 ANLKEELEDLKSQNGHLSEELASKEEALMVGEQRAQALDSKL---------LTVVE-HLE 2668

Query: 825  NRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKAN 884
               A L D    VEK    +  +    +++   L  E+Q L +  S +++      E+ +
Sbjct: 2669 TAQAELRDKSEQVEKHQEALRAQELTAEQEKGAL--ESQ-LDLLTSALEEERRRCAEQQS 2725

Query: 885  RTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKK 944
            R DL+E E     T +R L+  L     +       K  ++     +       + + ++
Sbjct: 2726 RLDLSEREQAGAATLIRQLKDELGAGGTKLAQFDKVKTCDVCKSGPDDQQGACFSCQQRE 2785

Query: 945  VLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYT 1004
             L E  ++  E      AQL E +     + + +++ ++ +      H   ++ +S    
Sbjct: 2786 KLQEDLKERQEAFLMSRAQLSEKEELRPAVELQLQQQSRAH------HAWMERAKSE--- 2836

Query: 1005 EQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEM 1064
                 E+ +     +    ++ AL +K+  A +S   ++ +  S L Q   +L   +E  
Sbjct: 2837 ---AAELQRSQQHPQDGQSKMAALTRKLQAALLSRKELMKE-NSALKQDAKRLAE-KEHA 2891

Query: 1065 QRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDD 1124
            + V    L++    EE++   RE +    + K  +L  EM+   +E   +S+    +   
Sbjct: 2892 KEVELSALEAAL--EEVKREKRELETSASKDK-VELRGEMDRLLSENHSLSAACGSLKLT 2948

Query: 1125 ANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLN-- 1182
              N+             LK  + EE  + RS   E   +  + L+   +   Q++ +   
Sbjct: 2949 IENMGQQKEAFSCQLEALKDSQAEELSRWRSQHAELKQQHESLLRSYQSTGAQMDAMRHV 3008

Query: 1183 TELTGHDVVNQ-EQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELW-- 1239
             E T  D +    + ++L+++ + L  +   L      ++  + +   ++ + + EL   
Sbjct: 3009 LEATERDALEAVRKSHRLETERDALEKQARELEGEHDRIKERMHTFSREKQWTVEELERE 3068

Query: 1240 KQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKL 1299
            KQ+  +R  + ++       +L     + E  +  +++S +E   K+  ++     +   
Sbjct: 3069 KQNSRRRLRELEENHSREASELGHANQQLEAEICRLRASAEELGEKLSELQSEN--KRMA 3126

Query: 1300 QDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSY 1359
            Q+ +E    L+E+ A+       L+ ++E E +                   L+ E Q+ 
Sbjct: 3127 QELQESSCTLEERSAESERSRSSLQLQLE-EALGRMETQTTELGAQVELNNLLQKEKQNL 3185

Query: 1360 KQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQK 1419
             Q  E     + ++ A +++               +N+ + ++LE    L  ++ E  Q+
Sbjct: 3186 SQHMEAMQTELGKKEALIQELQEVVSRHSQETVS-LNE-KVRILEDDKSLLQEELENVQE 3243

Query: 1420 THEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEK---ESELAILRLKMHENANHYETM 1476
            T +         +E E +   L++  +++++LT      +S+   L  ++  +++    +
Sbjct: 3244 TSDKV------KNEKEYLETVLLQNSEKVDELTESVAVLQSQNLELNSQLAASSHTNHRV 3297

Query: 1477 QKESEIERVKLIEELNVKITE-------SVSLNKQVAELNKALEEEVAKTNEMQTALENQ 1529
            ++E E E+++L+ EL  K+         S ++NK++ EL K   +E+ +    Q  +  Q
Sbjct: 3298 RQEKEEEQLRLVRELEEKLRAVQRGSQGSKTINKELQELLKEKHQEINQL--QQNCIRYQ 3355

Query: 1530 EIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQ 1566
            E+ I+ L     + Q  V     +++K     S  +Q
Sbjct: 3356 EV-ILQLESSSKSSQAAVEQLQRELEKSSEQLSAVRQ 3391



 Score = 76.2 bits (179), Expect = 7e-12
 Identities = 155/752 (20%), Positives = 300/752 (39%), Gaps = 76/752 (10%)

Query: 821  DELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEE-NQNLQISLSDMQQHY-NA 878
            DE   RL V  +    ++ QL    H+     +K+Q+L+   NQ L+  L+D Q+   ++
Sbjct: 604  DEDEQRLWVSQNELEKLQSQLASARHQQSRDAEKHQLLVTSLNQQLK-GLTDTQESLESS 662

Query: 879  LVEKAN---RT--------DLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIED 927
            LVEK     RT         L E+ S K + QLR+    L +  H   + I QK    E 
Sbjct: 663  LVEKETALARTCQQLELVSSLQEALSLK-ELQLREASDKLLQAEHSLDS-IWQKCSGSEK 720

Query: 928  LEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLE 987
               E   ++    +   VL EK +K        E  ++  +  ++  N   EEL+K+N  
Sbjct: 721  QCSELKAEVADLTQKLGVLKEKTQKQ-------EVTIESLQREVDQTN---EELDKLNTA 770

Query: 988  LIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYE 1047
             +++  Q          +    EI+ L  +L +KD EI AL+  ++      +S++  +E
Sbjct: 771  CLEERAQLIHD-----LQGCEREIDSLKDVLLEKDREISALSGHVSEC-TEQLSLLK-HE 823

Query: 1048 SKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIP 1107
             KL +    L  +E  + +  ++LL  ++         R  + Q  E +  +L   +   
Sbjct: 824  LKLKE--QNLIQVENALSKAERELLLLRES--------RSSEQQSLEDRLIQLGDSLKDA 873

Query: 1108 KTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTE 1167
            +TE + +    + ++     +                Q+EE  ++ R  +Q+Q       
Sbjct: 874  QTELVKVREHRDSLAAQVGALQEQAH-----------QDEESILELRGEVQKQMRSHGQR 922

Query: 1168 LQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSA 1227
            L E    I    +L  +L       QE  +QL+ +L +     +  L    E R+ + S 
Sbjct: 923  LSEGEAHI---TSLKDQLVAAAQKLQES-SQLQQQLSKKEESLEKELKASKEERNRLHSQ 978

Query: 1228 VDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIV 1287
             ++   E A+   Q L +++     T  E++       +   QL ++ +   + E     
Sbjct: 979  AEEYRKE-AQTVSQQLEEQKRSQGITRGEMKATAETAAALEAQLREAEKERQRLEAELKT 1037

Query: 1288 TMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIE--DEKVAFXXXXXXXXXXX 1345
               +   L + LQ K E++ NLQ     + ++ + L+ E+E   E++             
Sbjct: 1038 RDSEKEKLSSDLQSKAENISNLQNLLNSLKSEKQQLQEELEALTEELDLQKEKVRQLSQE 1097

Query: 1346 XXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLEL 1405
                 D RT  Q+  Q        + +E   L+++             RV+  EA+V E 
Sbjct: 1098 AASALDSRTSYQNQAQQLSAEAARLQQELDHLQRTLSELGCEAESRRDRVSVLEAQVSEN 1157

Query: 1406 THQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLK 1465
               ++    E      +  +TL ++    E+V Q L    +++     E++  LA L+ +
Sbjct: 1158 AAVIKALREE------KEELTLQKQELSSEHV-QGLASTAEQLRRSLAERDEALADLQAR 1210

Query: 1466 MHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTA 1525
                      +Q++    + +L E+ ++   E+ SL  +V       EE V+K      +
Sbjct: 1211 ADAQQKELTQLQEQERSLKTQLAEKEHLG-RENQSLKSEVGR----QEEAVSKLQSDAKS 1265

Query: 1526 LENQEIEIVTLNDEITNLQNMVRASSSKIQKH 1557
            L+ +  ++     ++ N +  +R    + Q+H
Sbjct: 1266 LQEKHSQVC---QQMENREETLRNVKRECQQH 1294



 Score = 75.8 bits (178), Expect = 9e-12
 Identities = 218/1159 (18%), Positives = 456/1159 (39%), Gaps = 115/1159 (9%)

Query: 240  LKDIESKDVRISS-LEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQ 298
            L+D++S++  +S  L    + L           SKL   +E               + K 
Sbjct: 2625 LEDLKSQNGHLSEELASKEEALMVGEQRAQALDSKLLTVVEHLETAQAELRDKSEQVEKH 2684

Query: 299  SIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKEL-ENKLATMGTESK 357
                  +E T  +EKG+LE + +  LT  +E  E   C  +Q+  +L E + A   T  +
Sbjct: 2685 QEALRAQELTAEQEKGALE-SQLDLLTSALEE-ERRRCAEQQSRLDLSEREQAGAATLIR 2742

Query: 358  AVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSL 417
             +      G   +++     T    KS          +    +K+ ++   + E  + S 
Sbjct: 2743 QLKDELGAGGTKLAQFDKVKTCDVCKSGPDDQQGACFSCQQREKLQEDLKERQEAFLMS- 2801

Query: 418  NKDLVDKEY----VISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTE 473
               L +KE     V  +                +  A+LQ   Q   +G S +   T   
Sbjct: 2802 RAQLSEKEELRPAVELQLQQQSRAHHAWMERAKSEAAELQRSQQHPQDGQSKMAALTRKL 2861

Query: 474  DV-----NEIAKVQEQLKQELNDEIKDVNVKDL-IEKLKSAEEQITQLNDEID-AANKNM 526
                    E+ K    LKQ+     +  + K++ +  L++A E++ +   E++ +A+K+ 
Sbjct: 2862 QAALLSRKELMKENSALKQDAKRLAEKEHAKEVELSALEAALEEVKREKRELETSASKDK 2921

Query: 527  IKVKS--------NHKLKLK--QMQKTIDNFSKVSDS---NKEIVR--LTEELHHLSQKV 571
            ++++         NH L      ++ TI+N  +  ++     E ++    EEL     + 
Sbjct: 2922 VELRGEMDRLLSENHSLSAACGSLKLTIENMGQQKEAFSCQLEALKDSQAEELSRWRSQH 2981

Query: 572  AELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEM-ENLAETRLKAISLLESQKFDLVQEL 630
            AEL+++  +L   L  Y S    + D  + ++E  E  A   ++    LE+++  L ++ 
Sbjct: 2982 AELKQQHESL---LRSYQSTGA-QMDAMRHVLEATERDALEAVRKSHRLETERDALEKQA 3037

Query: 631  HILQQKYDEVEDKLADIS--------QLQSDQVCSEIKSVHLEE----QIDALSASKKEL 678
              L+ ++D +++++   S        +L+ ++  S  +   LEE    +   L  + ++L
Sbjct: 3038 RELEGEHDRIKERMHTFSREKQWTVEELEREKQNSRRRLRELEENHSREASELGHANQQL 3097

Query: 679  ALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNY---IQEN------------MDLTDK 723
               I  L+   E+L   + +L+++ + +  +LQ     ++E             + L + 
Sbjct: 3098 EAEICRLRASAEELGEKLSELQSENKRMAQELQESSCTLEERSAESERSRSSLQLQLEEA 3157

Query: 724  LEKMSAEKIS-----ELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRI 778
            L +M  +        EL   +  E+Q+  Q    +  ++ +++  I+ ++  +S++    
Sbjct: 3158 LGRMETQTTELGAQVELNNLLQKEKQNLSQHMEAMQTELGKKEALIQELQEVVSRHSQET 3217

Query: 779  CRLEESIAVMEDRRYSLERKAD--QLGSYLQEKQKAYSEYTIQE-----DELVNRLAVLM 831
              L E + ++ED +  L+ + +  Q  S   + +K Y E  + +     DEL   +AVL 
Sbjct: 3218 VSLNEKVRILEDDKSLLQEELENVQETSDKVKNEKEYLETVLLQNSEKVDELTESVAVLQ 3277

Query: 832  DHDRVVEKQLLEIEHENKEL-QKKNQILLEENQNLQISLSDMQ-----------QHYNAL 879
              +  +  QL    H N  + Q+K +  L   + L+  L  +Q           +    L
Sbjct: 3278 SQNLELNSQLAASSHTNHRVRQEKEEEQLRLVRELEEKLRAVQRGSQGSKTINKELQELL 3337

Query: 880  VEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESA 939
             EK    +  +    +YQ  +  LES+ K      Q  + Q ++E+E    + +   +  
Sbjct: 3338 KEKHQEINQLQQNCIRYQEVILQLESSSK----SSQAAVEQLQRELEKSSEQLSAVRQKC 3393

Query: 940  IRDKKVLNEKYEKNIEYVTQ-----LEAQLQEYKNNIENLNMNVE-ELNKMNLELIDKH- 992
             R +  L+E  ++N+    Q      E+Q      ++ + + + E        E  DK  
Sbjct: 3394 SRAEAELSE--QRNLLQQAQQKRPGAESQRDPTALDLSHPSRSSEGHRESQPAEKADKEA 3451

Query: 993  -VQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLA 1051
             +Q+Q  Q     +Q   ++ +L   L   D E+ AL   + +++   +S +S   +   
Sbjct: 3452 VLQQQMAQLVLSKDQESKKVQELKQQLDSGDVELKALEGALRSSEAK-LSALSARPAG-P 3509

Query: 1052 QFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEG 1111
            + ++    + ++      QLL+     +     +R ++ ++ EL+ T L  +  I +   
Sbjct: 3510 EASSLWTQVHQQAGSEDHQLLEPGSVIKRSLQNIRVKEKEMDELRLTHLKLQRTIDQYSV 3569

Query: 1112 MIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQ-ERSVLQEQSAKLNTELQE 1170
               +   +     ANN D             ++  + + ++ E+ +L+ Q +  + E   
Sbjct: 3570 AAAAQQRQLFVLSANNADVCERAELMGAQVTELSAQVDRLEKEKDLLRRQLS--DREDAV 3627

Query: 1171 CYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQ 1230
            C T   QL+    +         E++  L + L+ L    D  +S++   + +  S   Q
Sbjct: 3628 CQT---QLQLQQAQKRRCLQAASERLEGLAAHLKTLLQSKDAEISSLLSCKDAQMSGYLQ 3684

Query: 1231 RGFEIAELWKQHLAQREADFQKTEHELRV---QLSAFESKYEQLLDSVQSSTQEETNKIV 1287
               ++    +   A  EA      H+      QL   ++K   L   V +S+QE      
Sbjct: 3685 ---QLQANGRSQAAAYEARLAALGHQREAAAGQLRGLQAKVRHLQVQVDTSSQESQQAAA 3741

Query: 1288 TMEQVTSLQNKLQDKEEHL 1306
             M+        LQ + E L
Sbjct: 3742 KMDAFRKSMAALQSERERL 3760



 Score = 66.5 bits (155), Expect = 6e-09
 Identities = 205/1148 (17%), Positives = 466/1148 (40%), Gaps = 126/1148 (10%)

Query: 212  EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLE---EANK--LLEAARFE 266
            E  K    +    + +  AE K + + LL+  +S   ++ ++    EA +   LEA R  
Sbjct: 2964 EALKDSQAEELSRWRSQHAELKQQHESLLRSYQSTGAQMDAMRHVLEATERDALEAVRKS 3023

Query: 267  ISLEHS-----KLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKT-------EIEEKG 314
              LE       K A+ELE                 + ++E    EK        E+EE  
Sbjct: 3024 HRLETERDALEKQARELEGEHDRIKERMHTFSREKQWTVEELEREKQNSRRRLRELEENH 3083

Query: 315  SLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKS 374
            S E +   EL    + LE   C++R + +EL  KL+ + +E+K ++   ++ S  +  +S
Sbjct: 3084 SREAS---ELGHANQQLEAEICRLRASAEELGEKLSELQSENKRMAQELQESSCTLEERS 3140

Query: 375  GRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTX 434
                        S+ S  +L    ++ + + E    E+  Q    +L+ KE         
Sbjct: 3141 AE----------SERSRSSLQLQLEEALGRMETQTTELGAQVELNNLLQKEK--QNLSQH 3188

Query: 435  XXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIK 494
                      K+ LI +LQ    +H +          T  +NE  ++ E  K  L +E++
Sbjct: 3189 MEAMQTELGKKEALIQELQEVVSRHSQ---------ETVSLNEKVRILEDDKSLLQEELE 3239

Query: 495  DVNVKDLIEKLKSAEEQ----ITQLNDEIDAANKNMIKVKS-NHKLKLKQMQKTIDNFSK 549
              NV++  +K+K+ +E     + Q ++++D   +++  ++S N +L  +    +  N   
Sbjct: 3240 --NVQETSDKVKNEKEYLETVLLQNSEKVDELTESVAVLQSQNLELNSQLAASSHTNHRV 3297

Query: 550  VSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLA 609
              +  +E +RL  EL    + V     ++G+     ++ +   +++ + ++++ +++   
Sbjct: 3298 RQEKEEEQLRLVRELEEKLRAV-----QRGSQGSKTINKELQELLK-EKHQEINQLQQNC 3351

Query: 610  ETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQID 669
                + I  LES        +  LQ++ ++  ++L+ +      Q CS  ++  L EQ +
Sbjct: 3352 IRYQEVILQLESSSKSSQAAVEQLQRELEKSSEQLSAVR-----QKCSRAEA-ELSEQRN 3405

Query: 670  ALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSA 729
             L  ++++           + Q   T  DL +         ++   E  D    L++  A
Sbjct: 3406 LLQQAQQKRPGA-------ESQRDPTALDLSHPSRSSEGHRESQPAEKADKEAVLQQQMA 3458

Query: 730  EKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVME 789
            + +      ++ +++SK         K+QE    +++ + EL   +  +   E  ++ + 
Sbjct: 3459 QLV------LSKDQESK---------KVQELKQQLDSGDVELKALEGALRSSEAKLSALS 3503

Query: 790  DRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENK 849
             R    E  A  L + + ++  +     ++   ++ R    + + RV EK++ E+   + 
Sbjct: 3504 ARPAGPE--ASSLWTQVHQQAGSEDHQLLEPGSVIKR---SLQNIRVKEKEMDELRLTHL 3558

Query: 850  ELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKR 909
            +LQ+            Q S++   Q     V  AN  D+ E  +     Q+ +L + + R
Sbjct: 3559 KLQRTID---------QYSVAAAAQQRQLFVLSANNADVCE-RAELMGAQVTELSAQVDR 3608

Query: 910  ITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKN 969
            +  E + L+ ++  + ED   +   Q++ A + ++ L    E+       LE      K 
Sbjct: 3609 LEKE-KDLLRRQLSDREDAVCQTQLQLQQA-QKRRCLQAASER-------LEGLAAHLKT 3659

Query: 970  NIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALN 1029
             +++ +  +  L       +  ++Q+ Q         Y   +  L    +    ++  L 
Sbjct: 3660 LLQSKDAEISSLLSCKDAQMSGYLQQLQANGRSQAAAYEARLAALGHQREAAAGQLRGLQ 3719

Query: 1030 QKINNAQVSYMSMVSDYE---SKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVR 1086
             K+ + QV   +   + +   +K+  F   +  ++ E +R+  +    +  N   ++ +R
Sbjct: 3720 AKVRHLQVQVDTSSQESQQAAAKMDAFRKSMAALQSERERLVSRCRTLETEN---RLGLR 3776

Query: 1087 EQDDQ---IKELKE--TKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXX 1141
              D +    K LK+   KL  +M+   +E  ++ + +    +D N V             
Sbjct: 3777 GPDGEGGASKGLKQEIRKLLNQMDDLNSENAMLRAQLVRYREDLNQVLSLKDDQLKLLLQ 3836

Query: 1142 LKVQEEEEFIQERSVLQEQ--SAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQL 1199
             +        Q+++  +EQ   A+L  + +E  ++ ++ + L  E    +   +E++   
Sbjct: 3837 KQQDAIRNLEQQKAAAEEQQREARLQVQQKEEESEALRAQ-LARERAQEEEEEEEEVAGG 3895

Query: 1200 KSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRV 1259
             ++L +L  E  +  +  AELR  I    + +G     +    LA+ +    +   E   
Sbjct: 3896 AAQLRRLQQELLSQRTLTAELRQHIQLLEEDQGRTSTLVEAARLAEDQPQLPQKLSESES 3955

Query: 1260 QLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQ 1319
            Q  +   + E L  ++ ++ Q++ ++++  E   +L+N     ++ LR  +  ++ V   
Sbjct: 3956 QGRSARLQNEALRKAM-AALQDDRDRLI--EDFKTLRN---GYDQELRESRAAFSRVERS 4009

Query: 1320 IEILRSEI 1327
            ++   S++
Sbjct: 4010 LQEASSDL 4017



 Score = 36.3 bits (80), Expect = 7.0
 Identities = 61/341 (17%), Positives = 136/341 (39%), Gaps = 11/341 (3%)

Query: 505  LKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNF-SKVSDSNKEIVRLTEE 563
            L+S  E++      ++  N+  ++         K +++ I    +++ D N E   L  +
Sbjct: 3753 LQSERERLVSRCRTLETENRLGLRGPDGEGGASKGLKQEIRKLLNQMDDLNSENAMLRAQ 3812

Query: 564  LHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQK 623
            L    + + ++   K + QL L+       I +   +K    E   E RL+     E  +
Sbjct: 3813 LVRYREDLNQVLSLKDD-QLKLLLQKQQDAIRNLEQQKAAAEEQQREARLQVQQKEEESE 3871

Query: 624  FDLVQELHILQQKYDEVEDKLA----DISQLQSDQVCSEIKSVHLEEQIDALSASKKELA 679
                Q      Q+ +E E+++A     + +LQ + +     +  L + I  L   +   +
Sbjct: 3872 ALRAQLARERAQEEEEEEEEVAGGAAQLRRLQQELLSQRTLTAELRQHIQLLEEDQGRTS 3931

Query: 680  LVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKI 739
             ++E  +L ++Q     K  E++ +    +LQN   E +       +   +++ E    +
Sbjct: 3932 TLVEAARLAEDQPQLPQKLSESESQGRSARLQN---EALRKAMAALQDDRDRLIEDFKTL 3988

Query: 740  NHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKA 799
             +    +++      +++ ER L   + +  +   +  +  L+ S          L    
Sbjct: 3989 RNGYDQELRESRAAFSRV-ERSLQEASSDLAVLAKQRDVLLLQMSALKSSQTHAELSGLV 4047

Query: 800  DQLGSYLQEKQKAYSEYTIQEDELVNRLAVLM-DHDRVVEK 839
            DQL   L EK++  S ++ Q D     +  L  + DR++E+
Sbjct: 4048 DQLSGALAEKERELSSHSRQLDAFSRSMGSLQNERDRLMEE 4088


>UniRef50_A2ERV4 Cluster: Putative uncharacterized protein; n=1;
            Trichomonas vaginalis G3|Rep: Putative uncharacterized
            protein - Trichomonas vaginalis G3
          Length = 1095

 Score =  135 bits (327), Expect = 8e-30
 Identities = 204/1058 (19%), Positives = 468/1058 (44%), Gaps = 99/1058 (9%)

Query: 507  SAEEQITQLNDEIDAAN---KNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEE 563
            +A + +T+ N+ I+  N   ++ ++ +S +    +Q +K     +K+ + N    +    
Sbjct: 60   AANKTVTEQNNRIEKLNSEIQHFVEKESKYVQIGEQAKKFAAERNKLMEENNLFRQANNN 119

Query: 564  LHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKA-ISLLESQ 622
            ++ + +  A+L EE   LQ  + +       E+D +K    ++N A   L   + L++ +
Sbjct: 120  VNEVVESAAKLREENKELQSKVNELQK----ENDDFKSKT-LQNQASALLGGFMGLVKGE 174

Query: 623  KFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVI 682
                 QE+  L+++++E E  LA IS  +++Q+  +++ +  E+       +  E   +I
Sbjct: 175  S----QEVTELRKRHNEREAILAKIST-ENNQLKEKLQKLEAEKN------NNSEYEQII 223

Query: 683  ENLKLDKEQLYGTIKDLENDKEDIMNK--------LQNYIQENMDLTDKLEKMSAEKIS- 733
            E +  + E L   +++  N  ++ + K        +++   +N  L+D+LEK+ +EK   
Sbjct: 224  EEITKENENLKSKLQNQNNSSDETLRKQLLEKDSTIKSLSDDNKSLSDELEKLDSEKEQK 283

Query: 734  --ELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDR 791
              E +AKIN  + S          KI E +L  + + + L + K     +      +E +
Sbjct: 284  EKEFIAKINELQNSLSNLNDKNKNKISELELQNQALNNSLIELKHNNETILMEKQQIETQ 343

Query: 792  RYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKEL 851
              +L  K  +L + LQ+ Q+  +  + Q+ ++++ L   ++   +  K L E+ +EN  L
Sbjct: 344  ISNLISKNSELETKLQKMQQMNAG-SEQDRDIISDLQKSLESSNIKAKNL-ELTNEN--L 399

Query: 852  QKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRIT 911
            QK+   L  E   L  ++  + Q     +E  N+ +  +  + K    L++ +  ++++ 
Sbjct: 400  QKEGNSLKLEISKLNSNIEKLNQEK---IENNNKINELQLNNEKSLENLQNHQKIIEKLN 456

Query: 912  HEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNI 971
             E +  I +K  +++ +  +    I++  +  + LN++  +N + + +L    ++ K NI
Sbjct: 457  QE-KIEITKKINDLQSVNDKSKENIQNYEKIIEKLNQEKIENTKKIDELNDVNEKSKENI 515

Query: 972  ENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQK 1031
            +N    +E+LN   LE  +  ++++ ++     E+  N ++ L    ++ D+ +    Q 
Sbjct: 516  QNNQKIIEKLNSKFLEF-ENQMKEKDSEIAKLQEENSNFVSNLQKSKEESDKNLTEKIQN 574

Query: 1032 INNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQ 1091
            + N +    + ++D   +  + T K +N+  E ++   Q     Q+ E+   L  ++   
Sbjct: 575  LINDRTKLNNTLNDLSKENKEITEKYQNLSSENEKTKSQ----NQNLEKNLDLATKELST 630

Query: 1092 IKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFI 1151
            IKE +  +L  +    +TE   ++   +   ++  N+             L + +E E I
Sbjct: 631  IKE-QNKELVKQNQDMQTE---LNDLKKFKQENLTNLQNY----------LNLMKESETI 676

Query: 1152 Q-ERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTEN 1210
            + E   L+       TELQ   + +  L+  +  L       +E    +  KL+Q N  N
Sbjct: 677  KTENKSLKTNLENATTELQTTKSNLQNLQKQSQNLEKRANSAEETAENVLQKLKQQNEIN 736

Query: 1211 DNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQ 1270
            +NL   +  L+    + + +R  +  E     + Q+  + +K   E + Q+   E+KY+ 
Sbjct: 737  NNLELNLQTLKQE--NEIQKRKIDEKEKILLQIQQQNEENEKKNSENKKQM---ETKYDI 791

Query: 1271 LLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDE 1330
            +++ ++    E  ++I           K + KE    NLQ+   + +N  +I   ++E+E
Sbjct: 792  MINDLKQEINELNDQI-----------KSKSKELDEINLQKVTENNMNHEKI--EKLENE 838

Query: 1331 KVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXX 1390
               +                +LR     + + +  S   +N EN  + K           
Sbjct: 839  NKMYSDRCSDLESQLQSMISELR-----HLKSERDSTPVLNSEN--VNKIIEGLREENKD 891

Query: 1391 XXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIED 1450
               +++++  +   L +     D EI +      + L+ +N++   ++Q++ E+  ++ +
Sbjct: 892  LSEKLSESLDRENNLLNDATNHDMEITK----LKVDLSNKNNQIIELKQKVTEFSTKVTN 947

Query: 1451 LTYEKESELAILRLKMHENANHYETMQKESEIERVKL--IEELNVKITESV-SLNKQVAE 1507
              +E+ SE      K+ E  + YE ++ E+EI   KL  ++++   ++++V  L + + +
Sbjct: 948  --FEEISE------KLKEKEHDYERIKNENEIANGKLQSLDKIRGDLSKTVDELRENLQK 999

Query: 1508 LNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQN 1545
             N +L +   +  +   A E     IV L   I  +++
Sbjct: 1000 TNLSLSKTQDELKQKNGAYEEAVKRIVKLMKYIKKIES 1037



 Score =  128 bits (310), Expect = 9e-28
 Identities = 181/942 (19%), Positives = 411/942 (43%), Gaps = 63/942 (6%)

Query: 638  DEVEDKLADISQLQS--DQVCSEIKSVH--LEEQIDALSASKKELALVIENLKLDKEQLY 693
            +++E+K   IS LQS  D   +E  + +  + EQ + +     E+   +E  +    Q+ 
Sbjct: 35   NDIEEKKTKISMLQSIIDTTTNERDAANKTVTEQNNRIEKLNSEIQHFVEK-ESKYVQIG 93

Query: 694  GTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSA--EKISELLAKINHEEQS----KI 747
               K    ++  +M +   + Q N ++ + +E  +   E+  EL +K+N  ++     K 
Sbjct: 94   EQAKKFAAERNKLMEENNLFRQANNNVNEVVESAAKLREENKELQSKVNELQKENDDFKS 153

Query: 748  QT-QFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYL 806
            +T Q    A +      ++    E+++ + R    E  +A +      L+ K  +L +  
Sbjct: 154  KTLQNQASALLGGFMGLVKGESQEVTELRKRHNEREAILAKISTENNQLKEKLQKLEAEK 213

Query: 807  Q---EKQKAYSEYTIQEDELVNRLAVLMDH-DRVVEKQLLEIEHENKELQKKNQILLEEN 862
                E ++   E T + + L ++L    +  D  + KQLLE +   K L   N+ L +E 
Sbjct: 214  NNNSEYEQIIEEITKENENLKSKLQNQNNSSDETLRKQLLEKDSTIKSLSDDNKSLSDEL 273

Query: 863  QNLQISLSDMQQHYNALVEK-----ANRTDLAESESTKYQTQLRDLESNLKRITHEHQTL 917
            + L       ++ + A + +     +N  D  +++ ++ + Q + L ++L  + H ++T+
Sbjct: 274  EKLDSEKEQKEKEFIAKINELQNSLSNLNDKNKNKISELELQNQALNNSLIELKHNNETI 333

Query: 918  IVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMN 977
            +++K+            QIE+ I +    N + E  ++ + Q+ A  ++ ++ I +L  +
Sbjct: 334  LMEKQ------------QIETQISNLISKNSELETKLQKMQQMNAGSEQDRDIISDLQKS 381

Query: 978  VEELN--KMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNA 1035
            +E  N    NLEL ++++QK+             EI+KLN+ +++ ++E I  N KIN  
Sbjct: 382  LESSNIKAKNLELTNENLQKEGNSLK-------LEISKLNSNIEKLNQEKIENNNKINEL 434

Query: 1036 QVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKEL 1095
            Q++    + +    L      +E + +E   ++K++ D +  N++ +  ++  +  I++L
Sbjct: 435  QLNNEKSLEN----LQNHQKIIEKLNQEKIEITKKINDLQSVNDKSKENIQNYEKIIEKL 490

Query: 1096 KETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEE--EFIQE 1153
             + K+     I +   +   S  E + ++   ++            +K ++ E  +  +E
Sbjct: 491  NQEKIENTKKIDELNDVNEKSK-ENIQNNQKIIEKLNSKFLEFENQMKEKDSEIAKLQEE 549

Query: 1154 RSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQ--EQINQLKSKLEQLNTEND 1211
             S       K   E  +  T+ IQ   +N     ++ +N   ++  ++  K + L++EN+
Sbjct: 550  NSNFVSNLQKSKEESDKNLTEKIQ-NLINDRTKLNNTLNDLSKENKEITEKYQNLSSENE 608

Query: 1212 NLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQL 1271
               S    L  ++  A  +    I E  K+ L ++  D Q   ++L+       +  +  
Sbjct: 609  KTKSQNQNLEKNLDLATKELS-TIKEQNKE-LVKQNQDMQTELNDLKKFKQENLTNLQNY 666

Query: 1272 LDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEK 1331
            L+ ++ S   +T        + +   +LQ  + +L+NLQ++  ++  +      E  +  
Sbjct: 667  LNLMKESETIKTENKSLKTNLENATTELQTTKSNLQNLQKQSQNLEKRANSAE-ETAENV 725

Query: 1332 VAFXXXXXXXXXXXXXXXXDLRTENQSYKQM---QEQSILNINEENAQL-KKSSXXXXXX 1387
            +                   L+ EN+  K+    +E+ +L I ++N +  KK+S      
Sbjct: 726  LQKLKQQNEINNNLELNLQTLKQENEIQKRKIDEKEKILLQIQQQNEENEKKNSENKKQM 785

Query: 1388 XXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKR 1447
                   +ND + ++ EL  Q++ K  E+ +   +        +++ E +  +   Y  R
Sbjct: 786  ETKYDIMINDLKQEINELNDQIKSKSKELDEINLQKVTENNMNHEKIEKLENENKMYSDR 845

Query: 1448 IEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITE--SVSLNKQV 1505
              DL  + +S ++ LR  +    +    +  E+  + ++ + E N  ++E  S SL+++ 
Sbjct: 846  CSDLESQLQSMISELR-HLKSERDSTPVLNSENVNKIIEGLREENKDLSEKLSESLDREN 904

Query: 1506 AELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMV 1547
              LN A   ++  T +++  L N+  +I+ L  ++T     V
Sbjct: 905  NLLNDATNHDMEIT-KLKVDLSNKNNQIIELKQKVTEFSTKV 945



 Score =  125 bits (301), Expect = 1e-26
 Identities = 185/1010 (18%), Positives = 425/1010 (42%), Gaps = 72/1010 (7%)

Query: 406  EIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPS- 464
            EI KL+  I+     +   + +I                ++  I +L  E Q  +E  S 
Sbjct: 29   EIGKLKNDIEEKKTKISMLQSIIDTTTNERDAANKTVTEQNNRIEKLNSEIQHFVEKESK 88

Query: 465  LIHVGTNTEDVNEIAKVQEQLKQELN-DEIKDVNVKDLIEKLKSAEEQITQLNDEIDAAN 523
             + +G   E   + A  + +L +E N     + NV +++E      E+  +L  +++   
Sbjct: 89   YVQIG---EQAKKFAAERNKLMEENNLFRQANNNVNEVVESAAKLREENKELQSKVNELQ 145

Query: 524  KNMIKVKSNHKLKLKQMQKTIDNF-SKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQ 582
            K     KS  K    Q    +  F   V   ++E+  L +  +     +A++  E   L+
Sbjct: 146  KENDDFKS--KTLQNQASALLGGFMGLVKGESQEVTELRKRHNEREAILAKISTENNQLK 203

Query: 583  LHLVDYDSGRMIESDVYKKMIEM-----ENL-AETRLKAISLLESQKFDLVQELHILQQK 636
              L   ++ +   S+ Y+++IE      ENL ++ + +  S  E+ +  L+++   ++  
Sbjct: 204  EKLQKLEAEKNNNSE-YEQIIEEITKENENLKSKLQNQNNSSDETLRKQLLEKDSTIKSL 262

Query: 637  YDEVEDKLADISQLQSDQVCSEIKSV-HLEEQIDALSASKKELALVIENLKLDKEQLYGT 695
             D+ +    ++ +L S++   E + +  + E  ++LS    +    I  L+L  + L  +
Sbjct: 263  SDDNKSLSDELEKLDSEKEQKEKEFIAKINELQNSLSNLNDKNKNKISELELQNQALNNS 322

Query: 696  IKDLENDKEDIM-------NKLQNYIQENMDLTDKLEKMSAEKI-SELLAKINHEEQSKI 747
            + +L+++ E I+        ++ N I +N +L  KL+KM      SE    I  + Q  +
Sbjct: 323  LIELKHNNETILMEKQQIETQISNLISKNSELETKLQKMQQMNAGSEQDRDIISDLQKSL 382

Query: 748  QTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLG---- 803
            ++    + K +  +L  EN++ E +  K  I +L  +I  +   +     K ++L     
Sbjct: 383  ESS---NIKAKNLELTNENLQKEGNSLKLEISKLNSNIEKLNQEKIENNNKINELQLNNE 439

Query: 804  ---SYLQEKQKAYSEYTIQEDELVNRLAVLM-----------DHDRVVEKQLLEIEHENK 849
                 LQ  QK   +   ++ E+  ++  L            ++++++EK   E     K
Sbjct: 440  KSLENLQNHQKIIEKLNQEKIEITKKINDLQSVNDKSKENIQNYEKIIEKLNQEKIENTK 499

Query: 850  ELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKR 909
            ++ + N +  +  +N+Q +   +++  +  +E  N+    +SE  K Q +  +  SNL++
Sbjct: 500  KIDELNDVNEKSKENIQNNQKIIEKLNSKFLEFENQMKEKDSEIAKLQEENSNFVSNLQK 559

Query: 910  ITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKN 969
               E    + +K + + +   + N  +    ++ K + EKY+       + ++Q Q  + 
Sbjct: 560  SKEESDKNLTEKIQNLINDRTKLNNTLNDLSKENKEITEKYQNLSSENEKTKSQNQNLEK 619

Query: 970  NIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTE-QYINEINKLNALLKQKDEEIIAL 1028
            N++     +  + + N EL+ K  Q  QT+  D  + +  N  N  N L   K+ E I  
Sbjct: 620  NLDLATKELSTIKEQNKELV-KQNQDMQTELNDLKKFKQENLTNLQNYLNLMKESETIKT 678

Query: 1029 NQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQ 1088
              K      S  + + +  ++L    + L+N++++ Q + K+   +++  E +   +++Q
Sbjct: 679  ENK------SLKTNLENATTELQTTKSNLQNLQKQSQNLEKRANSAEETAENVLQKLKQQ 732

Query: 1089 DD-------QIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXX 1141
            ++        ++ LK+     +  I + E +++    +   ++  N +            
Sbjct: 733  NEINNNLELNLQTLKQENEIQKRKIDEKEKILLQIQQQNEENEKKNSENKKQMETKYDIM 792

Query: 1142 L-----KVQEEEEFIQERS-VLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQ 1195
            +     ++ E  + I+ +S  L E + +  TE    + KI +LE  N   +      + Q
Sbjct: 793  INDLKQEINELNDQIKSKSKELDEINLQKVTENNMNHEKIEKLENENKMYSDRCSDLESQ 852

Query: 1196 INQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADF--QKT 1253
            +  + S+L  L +E D+     +E  + I   + +   +++E   + L  RE +     T
Sbjct: 853  LQSMISELRHLKSERDSTPVLNSENVNKIIEGLREENKDLSEKLSESL-DRENNLLNDAT 911

Query: 1254 EHELRV-QLSA-FESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQE 1311
             H++ + +L     +K  Q+++  Q  T+  T K+   E+++    + +   E ++N  E
Sbjct: 912  NHDMEITKLKVDLSNKNNQIIELKQKVTEFST-KVTNFEEISEKLKEKEHDYERIKNENE 970

Query: 1312 KYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQ 1361
                 +  ++ +R ++                       +L+ +N +Y++
Sbjct: 971  IANGKLQSLDKIRGDLSKTVDELRENLQKTNLSLSKTQDELKQKNGAYEE 1020



 Score =  109 bits (261), Expect = 8e-22
 Identities = 176/874 (20%), Positives = 363/874 (41%), Gaps = 54/874 (6%)

Query: 723  KLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLE 782
            K   + AE I +L   I  ++      Q  ID    ERD   + +  +     +RI +L 
Sbjct: 22   KCNNLEAE-IGKLKNDIEEKKTKISMLQSIIDTTTNERDAANKTVTEQ----NNRIEKLN 76

Query: 783  ESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLL 842
              I    ++    E K  Q+G   Q K+ A     + E+  + R A   + + VVE    
Sbjct: 77   SEIQHFVEK----ESKYVQIGE--QAKKFAAERNKLMEENNLFRQAN-NNVNEVVESAA- 128

Query: 843  EIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAES-ESTKYQTQLR 901
            ++  ENKELQ K   L +EN + +     +Q   +AL+         ES E T+ + +  
Sbjct: 129  KLREENKELQSKVNELQKENDDFKSKT--LQNQASALLGGFMGLVKGESQEVTELRKRHN 186

Query: 902  DLESNLKRITHEHQTLI--VQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYE-KNIEYVT 958
            + E+ L +I+ E+  L   +QK +  ++   E+   IE   ++ + L  K + +N     
Sbjct: 187  EREAILAKISTENNQLKEKLQKLEAEKNNNSEYEQIIEEITKENENLKSKLQNQNNSSDE 246

Query: 959  QLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALL 1018
             L  QL E  + I++L+ + + L+   LE +D   ++++ +      +  N ++ LN   
Sbjct: 247  TLRKQLLEKDSTIKSLSDDNKSLSD-ELEKLDSEKEQKEKEFIAKINELQNSLSNLNDKN 305

Query: 1019 KQKDEEIIALNQKINNAQV-------SYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQL 1071
            K K  E+   NQ +NN+ +       + +      E++++   +K   +E ++Q++ +  
Sbjct: 306  KNKISELELQNQALNNSLIELKHNNETILMEKQQIETQISNLISKNSELETKLQKMQQMN 365

Query: 1072 LDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXX 1131
              S+Q  + +  L +  +    + K  +LT E N+ K EG  +   I  ++ +   ++  
Sbjct: 366  AGSEQDRDIISDLQKSLESSNIKAKNLELTNE-NLQK-EGNSLKLEISKLNSNIEKLNQE 423

Query: 1132 XXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVV 1191
                      L++  E+  ++     Q+   KLN E  E   KI  L+++N + +  ++ 
Sbjct: 424  KIENNNKINELQLNNEKS-LENLQNHQKIIEKLNQEKIEITKKINDLQSVNDK-SKENIQ 481

Query: 1192 NQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQ 1251
            N E+I +   KL Q   EN   +  + ++       + Q   +I E       + E   +
Sbjct: 482  NYEKIIE---KLNQEKIENTKKIDELNDVNEKSKENI-QNNQKIIEKLNSKFLEFENQMK 537

Query: 1252 KTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTM-EQVTSLQNKLQDKEEHLRNLQ 1310
            + + E+        +    L  S + S +  T KI  +    T L N L D  +  + + 
Sbjct: 538  EKDSEIAKLQEENSNFVSNLQKSKEESDKNLTEKIQNLINDRTKLNNTLNDLSKENKEIT 597

Query: 1311 EKYADVINQIEILRSEIED-EK-----VAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQE 1364
            EKY ++ ++ E  +S+ ++ EK                        D++TE    K+ ++
Sbjct: 598  EKYQNLSSENEKTKSQNQNLEKNLDLATKELSTIKEQNKELVKQNQDMQTELNDLKKFKQ 657

Query: 1365 QSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYT 1424
            +++ N+ +    L K S             + +A       T +L+   S + Q   + +
Sbjct: 658  ENLTNL-QNYLNLMKESETIKTENKSLKTNLENA-------TTELQTTKSNL-QNLQKQS 708

Query: 1425 ITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIER 1484
              L +R +  E   + +++  K+  ++      EL +  LK        +  +KE  + +
Sbjct: 709  QNLEKRANSAEETAENVLQKLKQQNEIN--NNLELNLQTLKQENEIQKRKIDEKEKILLQ 766

Query: 1485 VKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQ 1544
            ++   E N K   S +  +   + +  + +   + NE+   ++++  E+  +N +     
Sbjct: 767  IQQQNEENEK-KNSENKKQMETKYDIMINDLKQEINELNDQIKSKSKELDEINLQKVTEN 825

Query: 1545 NMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNK 1578
            NM      K++      SD     + QL + +++
Sbjct: 826  NMNHEKIEKLENENKMYSDRCSDLESQLQSMISE 859



 Score = 92.3 bits (219), Expect = 1e-16
 Identities = 170/774 (21%), Positives = 324/774 (41%), Gaps = 53/774 (6%)

Query: 151  IKEKDNALSVLQVKMKIMETTILDLQEKINEKDQI-IEAKNKATTXXXXXXXXXXXXXXX 209
            I E  N+LS L  K K  + + L+LQ +      I ++  N+                  
Sbjct: 291  INELQNSLSNLNDKNK-NKISELELQNQALNNSLIELKHNNETILMEKQQIETQISNLIS 349

Query: 210  XXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISL 269
               + + ++ KMQ+     E + +D    L K +ES +++  +LE  N+ L+     + L
Sbjct: 350  KNSELETKLQKMQQMNAGSEQD-RDIISDLQKSLESSNIKAKNLELTNENLQKEGNSLKL 408

Query: 270  EHSKLAQELEQXXXXXXXXXXXXXXLA---KQSIEPSCEEKTEIEEKGSLEIANMTELTK 326
            E SKL   +E+              L    ++S+E + +   +I EK + E     E+TK
Sbjct: 409  EISKLNSNIEKLNQEKIENNNKINELQLNNEKSLE-NLQNHQKIIEKLNQE---KIEITK 464

Query: 327  KIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPW 386
            KI  L+ +N + ++  +  E  +  +  E K  ++        ++ KS  N  +  K   
Sbjct: 465  KINDLQSVNDKSKENIQNYEKIIEKLNQE-KIENTKKIDELNDVNEKSKENIQNNQKI-I 522

Query: 387  SQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKD 446
             +L+S+ L  +   K   +EIAKL    Q  N + V       E+              D
Sbjct: 523  EKLNSKFLEFENQMKEKDSEIAKL----QEENSNFVSNLQKSKEESDKNLTEKIQNLIND 578

Query: 447  TLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQ-LKQELNDEIKDVN-VKDLIEK 504
                   L +    E   +     N    NE  K Q Q L++ L+   K+++ +K+  ++
Sbjct: 579  RTKLNNTL-NDLSKENKEITEKYQNLSSENEKTKSQNQNLEKNLDLATKELSTIKEQNKE 637

Query: 505  L-KSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEE 563
            L K  ++  T+LND      +N+  ++  + L L +  +TI   +K   +N E    T E
Sbjct: 638  LVKQNQDMQTELNDLKKFKQENLTNLQ--NYLNLMKESETIKTENKSLKTNLE--NATTE 693

Query: 564  LHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQK 623
            L      +  L+++  NL+      +S      +V +K+ +   +          LE   
Sbjct: 694  LQTTKSNLQNLQKQSQNLEKRA---NSAEETAENVLQKLKQQNEINNN-------LELNL 743

Query: 624  FDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIE 683
              L QE  I ++K DE E  L  I Q Q+++  +E K+   ++Q++       +  ++I 
Sbjct: 744  QTLKQENEIQKRKIDEKEKILLQIQQ-QNEE--NEKKNSENKKQMET------KYDIMIN 794

Query: 684  NLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEK--ISELLAKINH 741
            +LK +  +L   IK    + ++I   LQ   + NM+  +K+EK+  E    S+  + +  
Sbjct: 795  DLKQEINELNDQIKSKSKELDEI--NLQKVTENNMN-HEKIEKLENENKMYSDRCSDLES 851

Query: 742  EEQSKIQTQFGIDAKIQERD-LYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKA- 799
            + QS I     + ++      L  EN+   +   +     L E ++   DR  +L   A 
Sbjct: 852  QLQSMISELRHLKSERDSTPVLNSENVNKIIEGLREENKDLSEKLSESLDRENNLLNDAT 911

Query: 800  --DQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQI 857
              D   + L+      +   I+  + V   +  + +   + ++L E EH+ + ++ +N+I
Sbjct: 912  NHDMEITKLKVDLSNKNNQIIELKQKVTEFSTKVTNFEEISEKLKEKEHDYERIKNENEI 971

Query: 858  LLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRD-LESNLKRI 910
               + Q+L     D+ +  + L E   +T+L+ S++     Q     E  +KRI
Sbjct: 972  ANGKLQSLDKIRGDLSKTVDELRENLQKTNLSLSKTQDELKQKNGAYEEAVKRI 1025



 Score = 85.8 bits (203), Expect = 9e-15
 Identities = 136/721 (18%), Positives = 303/721 (42%), Gaps = 59/721 (8%)

Query: 897  QTQLRDLESNLKRITHEHQTL---IVQKKKEIEDLEIEFNTQIESAIRDKKVLNE--KYE 951
            +T++  L+S +   T+E       + ++   IE L  E    +E   +  ++  +  K+ 
Sbjct: 41   KTKISMLQSIIDTTTNERDAANKTVTEQNNRIEKLNSEIQHFVEKESKYVQIGEQAKKFA 100

Query: 952  KNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEI 1011
                 + +     ++  NN+  +  +  +L + N EL  K V + Q ++ D+  + +   
Sbjct: 101  AERNKLMEENNLFRQANNNVNEVVESAAKLREENKELQSK-VNELQKENDDFKSKTLQ-- 157

Query: 1012 NKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQL 1071
            N+ +ALL      +   +Q++   +  +    ++ E+ LA+ +T+   ++E++Q++  + 
Sbjct: 158  NQASALLGGFMGLVKGESQEVTELRKRH----NEREAILAKISTENNQLKEKLQKLEAEK 213

Query: 1072 LDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXX 1131
             ++ ++ + ++ + +E ++   +L+    + +  + K + +   STI+ +SDD  ++   
Sbjct: 214  NNNSEYEQIIEEITKENENLKSKLQNQNNSSDETLRK-QLLEKDSTIKSLSDDNKSLSDE 272

Query: 1132 XXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKI-IQLETLNTELTG--H 1188
                       K Q+E+EFI + + LQ   + LN + +   +++ +Q + LN  L    H
Sbjct: 273  LEKLDSE----KEQKEKEFIAKINELQNSLSNLNDKNKNKISELELQNQALNNSLIELKH 328

Query: 1189 D----VVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVD-----QRGFEIAELW 1239
            +    ++ ++QI    S L   N+E +  L  + ++ +      D     Q+  E + + 
Sbjct: 329  NNETILMEKQQIETQISNLISKNSELETKLQKMQQMNAGSEQDRDIISDLQKSLESSNIK 388

Query: 1240 KQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKI--VTMEQVTSLQN 1297
             ++L     + QK  + L++++S   S  E+L         E  NKI  + +    SL+N
Sbjct: 389  AKNLELTNENLQKEGNSLKLEISKLNSNIEKL----NQEKIENNNKINELQLNNEKSLEN 444

Query: 1298 KLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKV------AFXXXXXXXXXXXXXXXXD 1351
             LQ+ ++ +  L ++  ++  +I  L+S  +  K                         +
Sbjct: 445  -LQNHQKIIEKLNQEKIEITKKINDLQSVNDKSKENIQNYEKIIEKLNQEKIENTKKIDE 503

Query: 1352 LRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLEL 1411
            L   N+  K+  + +   I + N++  +                 +    V  L    E 
Sbjct: 504  LNDVNEKSKENIQNNQKIIEKLNSKFLEFENQMKEKDSEIAKLQEENSNFVSNLQKSKEE 563

Query: 1412 KDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKE---SELAILRLKMHE 1468
             D  + +K        T+ N+   ++ ++  E  ++ ++L+ E E   S+   L   +  
Sbjct: 564  SDKNLTEKIQNLINDRTKLNNTLNDLSKENKEITEKYQNLSSENEKTKSQNQNLEKNLDL 623

Query: 1469 NANHYETMQKESEIERVKLIEELNVKITE-----SVSLNKQVAELNKALEEEVAKTNE-- 1521
                  T+ KE   E VK  +++  ++ +       +L      LN   E E  KT    
Sbjct: 624  ATKELSTI-KEQNKELVKQNQDMQTELNDLKKFKQENLTNLQNYLNLMKESETIKTENKS 682

Query: 1522 MQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQL--DNTMNKE 1579
            ++T LEN   E+ T    + NLQ      S  ++K  + A +T +   ++L   N +N  
Sbjct: 683  LKTNLENATTELQTTKSNLQNLQK----QSQNLEKRANSAEETAENVLQKLKQQNEINNN 738

Query: 1580 L 1580
            L
Sbjct: 739  L 739



 Score = 61.7 bits (143), Expect = 2e-07
 Identities = 81/448 (18%), Positives = 196/448 (43%), Gaps = 24/448 (5%)

Query: 1157 LQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLST 1216
            L+ +  KL  +++E  TKI  L+++    T       + + +  +++E+LN+E  + +  
Sbjct: 26   LEAEIGKLKNDIEEKKTKISMLQSIIDTTTNERDAANKTVTEQNNRIEKLNSEIQHFVEK 85

Query: 1217 VAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTE-----HELRVQLSAFESKYEQL 1271
             ++    I     +   E  +L +++   R+A+    E      +LR +    +SK  +L
Sbjct: 86   ESKY-VQIGEQAKKFAAERNKLMEENNLFRQANNNVNEVVESAAKLREENKELQSKVNEL 144

Query: 1272 L---DSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIE 1328
                D  +S T +     +    +  ++ + Q+  E LR    +   ++ +I    ++++
Sbjct: 145  QKENDDFKSKTLQNQASALLGGFMGLVKGESQEVTE-LRKRHNEREAILAKISTENNQLK 203

Query: 1329 DEKVAFXXXXXXXXXXXXXXXXDLRTENQSYK-QMQEQSILNINEENAQLKKSSXXXXXX 1387
             EK+                  ++  EN++ K ++Q Q+    N  +  L+K        
Sbjct: 204  -EKLQKLEAEKNNNSEYEQIIEEITKENENLKSKLQNQN----NSSDETLRKQLLEKDST 258

Query: 1388 XXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKR 1447
                         ++ +L  + E K+ E   K +E   +L+  ND+ +N   +L    + 
Sbjct: 259  IKSLSDDNKSLSDELEKLDSEKEQKEKEFIAKINELQNSLSNLNDKNKNKISELELQNQA 318

Query: 1448 IEDLTYE-KESELAILRLKMHENANHYETMQKESEIE-RVKLIEELNVKITESVSLNKQV 1505
            + +   E K +   IL  K          + K SE+E +++ ++++N    +   +   +
Sbjct: 319  LNNSLIELKHNNETILMEKQQIETQISNLISKNSELETKLQKMQQMNAGSEQDRDI---I 375

Query: 1506 AELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNL-QNMVRASSSKIQKHVSFASDT 1564
            ++L K+LE    K   ++   EN + E  +L  EI+ L  N+ + +  KI+ + +  ++ 
Sbjct: 376  SDLQKSLESSNIKAKNLELTNENLQKEGNSLKLEISKLNSNIEKLNQEKIENN-NKINEL 434

Query: 1565 KQGRDEQLDNTMN-KELLDAVPRAELDL 1591
            +   ++ L+N  N +++++ + + ++++
Sbjct: 435  QLNNEKSLENLQNHQKIIEKLNQEKIEI 462


>UniRef50_Q7SHZ4 Cluster: Putative uncharacterized protein NCU00658.1;
            n=1; Neurospora crassa|Rep: Putative uncharacterized
            protein NCU00658.1 - Neurospora crassa
          Length = 4007

 Score =  135 bits (327), Expect = 8e-30
 Identities = 262/1403 (18%), Positives = 579/1403 (41%), Gaps = 105/1403 (7%)

Query: 213  DTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLE----EANKLLEAA----R 264
            D K ++ + +  F   +A  + E   L   ++ K  ++SS E    E  KL EA     R
Sbjct: 1355 DLKAELKQDRAEFDKKKALLEGEVATLQGKVDDKSSKLSSKEAEFNELKKLNEAQIAELR 1414

Query: 265  FEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEE-KTEIEEKGSLEIANMTE 323
             +++ + + L  +LE+                 Q  E   +  K + E K S    N T 
Sbjct: 1415 KDVADKSNSLQDKLEELSDLKGQQKTRIEDFNVQINEKMAQLLKAQNELKASQASLNTTT 1474

Query: 324  LTKKIELLEHLNCQIRQTNKELENK--LATMGTESKAVSSPSKKGSPLISRKSGRNTASK 381
             T+    +  L   +++   EL+ K   AT  TE   V            +K      ++
Sbjct: 1475 -TEYDAKIAQLEKSLKEKKDELKRKEGAATSSTEQNTVQLNKLNDDVKDKQKKLDEQQAE 1533

Query: 382  MKSPWSQLSSET--LNQ---DTDKKINKNEIAKLEMVIQSLNKDLVDK-EYVISEKDTXX 435
            + +  ++  +ET  LNQ   DT  K+ + E   +++  +  +KD +D  E  I+EK T  
Sbjct: 1534 LNNLKTKHQAETTDLNQTIKDTKAKLKQKETELIDL--KKKHKDRLDTLEKTIAEKQTTL 1591

Query: 436  XXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKD 495
                     K+T +  L+ +++ +M   +   +G  T ++ +       L+Q+ +D  K 
Sbjct: 1592 AQ-------KETELENLKAQNRTNMMNTNR-EIGDKTAELLKKEGELRDLRQKYDDAQKL 1643

Query: 496  VN-VKDLIEKLKSAEEQITQLNDEIDAANKN---MIKVKSNHKLKLKQMQKTIDNFSKVS 551
             +  K+    +   ++ I     E++ A K+   + K  ++ K ++K ++ ++   SK +
Sbjct: 1644 ADGSKEKDLAIAQYKQIIATKTSELEKAKKDVAALTKDVNDQKARIKDLESSVS--SKRA 1701

Query: 552  DSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAET 611
            D  K+   +++      + +  L  +  + +  L   ++    E    K         + 
Sbjct: 1702 DLKKKETEISDLKRQYEENIKRLNNDLSSQKATLTAKEN----EIAALKSGNASRLSRDI 1757

Query: 612  RLKAISLLESQKF--DLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQID 669
            + KA  L +  +   +L  +L  LQ+K +++  K +D ++LQ+D      K     +++ 
Sbjct: 1758 QEKASELAQKNQLVANLKVQLDGLQKKQNDLLQKGSDAAKLQADVDSLNKKISEKRQKVT 1817

Query: 670  ALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSA 729
             L     +L      L  +K ++    +++ + K+D+ ++     + + ++TD  + +S 
Sbjct: 1818 ELEGKVNKLD---SELAEEKARVSRRDREITDLKKDVSDEKARTTKRDREITDLKKDVSD 1874

Query: 730  EKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVME 789
            EK    +++ + E     +      A+  + D  I  ++S+L   ++    LE+ I   +
Sbjct: 1875 EKAR--VSRRDREVTDLKKDVSDEKARTTKHDNEIGGLQSKLDAKQASKEMLEQDI---K 1929

Query: 790  DRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELV----NRLAVLMDHDRVVEKQLLEIE 845
            D +   E++   L S +  K K    Y      L          L +     EK+L EI+
Sbjct: 1930 DLKAKQEKEVASLTSQILAKSKEIVGYERDLSSLKADYQKETTKLKNEISQKEKELAEIQ 1989

Query: 846  HENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLES 905
              NK+L   N  + E+   L  S + ++     + +K ++    E+++ K Q  + + ++
Sbjct: 1990 KTNKKL---NADIKEKEATLTASQAKVKDLNREVQQKKDQIKDFEAQNAKLQIDIENKKA 2046

Query: 906  NLKRITHEHQTLIVQKKKEIEDLE-IEFNT-QIESAIRDKKVLNEKYEKNIEYVTQLEAQ 963
             ++RI  E +TL  +  K I  +E +E    ++  +  +K+   ++Y+ ++    + EA+
Sbjct: 2047 EIERIKEERRTLNTEADKSIARIEGLERKIKELTGSSAEKEAQMKQYQADLAAKAETEAR 2106

Query: 964  LQEYKNNIENLNMNVEELNKM----NLELIDKHVQKQQTQSPDYTEQYINEINKLNALLK 1019
            +++ + ++   + ++ E  K     N++  +       TQ      +   EI      ++
Sbjct: 2107 IKQLERDLATKSNSLAEFEKKYKRANMDANNYRSSLAHTQGE--VAKLEEEIKTTKGDVQ 2164

Query: 1020 QKDEEIIALN---QKINNAQVSYMSM-VSDYESKLAQFTTKLENMEEEMQRVSKQLLDSK 1075
              ++++I      QKI + QV  + M V D    L     +++ +++   R+S+ L+  K
Sbjct: 2165 YWEDQMIMNQEETQKIQD-QVDRLKMDVKDKNKILEDHEKEIQTLKDTATRLSQDLIHKK 2223

Query: 1076 QHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXX 1135
               E     ++   +Q+ +L +      + +   +G I    ++   DD N         
Sbjct: 2224 SELEGSNSELQRVKNQVAQLTQDNKDQRVVVDTKDGEI--RKLQREVDDLNT----HVMD 2277

Query: 1136 XXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQ 1195
                   + ++ ++   E    ++  +   T L+E   +I +L   N +LT        +
Sbjct: 2278 KGDQLMKRGEDIKKLRDEIKNFKKDISDHETTLEETMAEIEKLSADNKQLTA-------E 2330

Query: 1196 INQLKSKLEQLNTENDNLLSTVAELRSSISS-AVDQRGFE--IAELWKQHLAQREADFQK 1252
            I+  K KL+Q  TE D L + + +++S+      D +  E  +AE  K+    +++   +
Sbjct: 2331 ISSYKDKLKQSQTEADALNNDIKDMKSTKEKLGQDAKAKETVLAEKMKEIQGLKDS-INR 2389

Query: 1253 TEHELRVQLSAFESKYE---QLLDSVQSSTQE-ETNKIVTMEQVTSLQNKLQDKEEHLRN 1308
               ++  + +  + K E   QL D ++++    +T +    ++   L +K +D       
Sbjct: 2390 LNQDISTKNATLDDKREIIDQLKDDIKTANSTIDTLRKDVKDKDAILAHKTKDVVARDAE 2449

Query: 1309 LQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQ----- 1363
            L +  A++ ++   L  + E+ K AF                D+ T+     Q +     
Sbjct: 2450 LAKLKAEIASKNAALAKKTEEAK-AFEKNVQTLTDQAKGLNQDVATKTTQLAQDRATISK 2508

Query: 1364 -EQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHE 1422
              + I ++  +  +LK+               +   +A + +L  +L  K++ + +KT E
Sbjct: 2509 LNKDIFDLKTDVTKLKQELSTKDANLTQKAGEIGSRDAGLAKLREELRAKEAALAKKTEE 2568

Query: 1423 YTI---TLTQRNDEFENVRQQLVEYEKRI-EDLTYEKESELAILRLKMHENANHYETMQK 1478
             +     + +  DE   +++ +   + ++ +D     + E  I +L    +       QK
Sbjct: 2569 ASSLEKNVKKLTDEATGLKKDVTSRDTQLAQDKDAISKLEKDIAKLNQELSTKDASLTQK 2628

Query: 1479 ESEI-----ERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEI 1533
              E+     E  KL EE+ VK T      +++  LN++++ +  +  + +  +E  E E+
Sbjct: 2629 TGEVGSKNAELAKLREEIRVKETALAKKTEELKGLNQSVDAKDTQLAQDKIKIERLEKEV 2688

Query: 1534 VTLNDEITNLQNMVRASSSKIQK 1556
              L  +I  L+  V        K
Sbjct: 2689 KGLTADIVKLREDVAFKDKSFAK 2711



 Score =  134 bits (324), Expect = 2e-29
 Identities = 275/1415 (19%), Positives = 580/1415 (40%), Gaps = 137/1415 (9%)

Query: 240  LKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQS 299
            LKDI+S  +   SLE+  + ++A       E   L Q+L Q               A Q 
Sbjct: 776  LKDIQSLRLENKSLEDQRQRVQA-------EKEVLQQQLSQTKARLEKVETTLKNTASQK 828

Query: 300  IEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAV 359
            ++   +     + K  LE   ++ L K+++L    +        + E  +A   T  + +
Sbjct: 829  MDLETQRNEWSKAKKVLE-EEISRLKKEVDLARKNSAAPTIVEIKPEPNIAESITRVEQL 887

Query: 360  SSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNK 419
                K   PL +R   +   +K+K      +    + D  + + +  I  L  V++    
Sbjct: 888  MKEQKPQLPLTARDFVQGLVAKLKD-----AQGHKDLDASEDVIRECIGLLNRVLKEPVF 942

Query: 420  DLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIA 479
            D  DKE + + ++            ++   AQLQ    ++ EG             +EI 
Sbjct: 943  DEKDKEMLQTLQNELNEALRKGKEDREQ-SAQLQSIIDKY-EGEKESLEKEVKVHKDEIK 1000

Query: 480  KVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQ 539
            K+++++ ++          +D+++  +S EEQI  LN +     K   ++K  H+ +L Q
Sbjct: 1001 KLKQEITEKKTSLANKQQERDMLK--ESYEEQIKNLNAD---HKKAAAELKVKHQNELTQ 1055

Query: 540  MQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVY 599
            ++K         D + +   L ++L  L Q   + E E+  LQ    DY + +   + + 
Sbjct: 1056 LRK---------DGDLKETNLLQKLDTLRQ---QNESERNRLQ---ADYAAEK---AKLT 1097

Query: 600  KKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEV----EDKLADISQLQSDQV 655
            K +   + L   + K ++ L+S+K   ++EL   Q+K  E+      K  D+ QL++  +
Sbjct: 1098 KDIEAQKKLVAQKEKDLAELKSKKEKEIKEL--TQKKDVEIATLKSTKQVDMEQLKNRHL 1155

Query: 656  CSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQL--YGTIKD---LENDKEDIMNKL 710
              E + +  + Q   +   + E+A + E  K D ++L    T +D   L+  + ++ N  
Sbjct: 1156 -QETEILRKQHQ-SRVGELESEIATIKEKYKKDLDELSRNNTSQDAIKLKQHENELANFK 1213

Query: 711  QNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQF-----GIDAKIQERDLYIE 765
              Y QE   L  +  K   E +++      + E+ K+ TQ+      + A++ ++   + 
Sbjct: 1214 AKYEQEKKQLAVQ-HKTEMESLTD-----RYHEKEKLATQYQERVQALSAELADKKTALA 1267

Query: 766  NIESELSKYKSRICRLEESIAVMEDRRYSLERK------ADQLGSYLQEKQKAYSEYTI- 818
              + +LS  K+++ +L+    V  D   +  +       AD  G+  + + K   E  + 
Sbjct: 1268 EYKEQLSASKAQLDKLKADHGVKVDELQAKLKSEVAKVTADYEGNLSELRTKHQGEVNVL 1327

Query: 819  ---QEDELVNRLAVLMDHDRVVEKQL----LEIEHENKELQKKNQILLEENQNLQISLSD 871
                +DE+    A   +  R +E ++     E++ +  E  KK  +L  E   LQ  + D
Sbjct: 1328 KVHHQDEIKKLTAGHNEKIRNLEHRINDLKAELKQDRAEFDKKKALLEGEVATLQGKVDD 1387

Query: 872  MQQHYNALVEKANR-TDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEI 930
                 ++   + N    L E++  + +  + D  ++L+    E   L  Q+K  IED   
Sbjct: 1388 KSSKLSSKEAEFNELKKLNEAQIAELRKDVADKSNSLQDKLEELSDLKGQQKTRIED--- 1444

Query: 931  EFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELID 990
             FN QI          NEK  + ++   +L+A            +  + +L K   E  D
Sbjct: 1445 -FNVQI----------NEKMAQLLKAQNELKASQASLNTTTTEYDAKIAQLEKSLKEKKD 1493

Query: 991  KHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKL 1050
            + +++++  +   TEQ   ++NKLN  +K K +++     ++NN +  + +  +D    +
Sbjct: 1494 E-LKRKEGAATSSTEQNTVQLNKLNDDVKDKQKKLDEQQAELNNLKTKHQAETTDLNQTI 1552

Query: 1051 AQFTTKLENMEEE---MQRVSKQLLDSKQHN-EELQILVREQDDQIKELKETKLTFEMNI 1106
                 KL+  E E   +++  K  LD+ +    E Q  + +++ +++ LK    T  MN 
Sbjct: 1553 KDTKAKLKQKETELIDLKKKHKDRLDTLEKTIAEKQTTLAQKETELENLKAQNRTNMMNT 1612

Query: 1107 PKTEGMIISSTIEPMSD--DANNV--DXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSA 1162
             +  G   +  ++   +  D      D            L + + ++ I  ++   E++ 
Sbjct: 1613 NREIGDKTAELLKKEGELRDLRQKYDDAQKLADGSKEKDLAIAQYKQIIATKTSELEKAK 1672

Query: 1163 K----LNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQ-LNTENDNLLSTV 1217
            K    L  ++ +   +I  LE+  +         + +I+ LK + E+ +   N++L S  
Sbjct: 1673 KDVAALTKDVNDQKARIKDLESSVSSKRADLKKKETEISDLKRQYEENIKRLNNDLSSQK 1732

Query: 1218 AELRSSISSAVDQRGFEIAELWK--QHLAQREADFQKTEHELRVQLSAFESKYEQLLDSV 1275
            A L +  +     +    + L +  Q  A   A   +    L+VQL   + K   LL   
Sbjct: 1733 ATLTAKENEIAALKSGNASRLSRDIQEKASELAQKNQLVANLKVQLDGLQKKQNDLLQKG 1792

Query: 1276 QSSTQ-----EETNKIVT--MEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIE 1328
              + +     +  NK ++   ++VT L+ K+   +  L   + + +    +I  L+ ++ 
Sbjct: 1793 SDAAKLQADVDSLNKKISEKRQKVTELEGKVNKLDSELAEEKARVSRRDREITDLKKDVS 1852

Query: 1329 DEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXX 1388
            DEK                   D+  E     + +++ + ++ ++ +  K  +       
Sbjct: 1853 DEK----ARTTKRDREITDLKKDVSDEKARVSR-RDREVTDLKKDVSDEKARTTKHDNEI 1907

Query: 1389 XXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRI 1448
                 ++ DA+    E+  Q ++KD +  Q+    ++T      +     +++V YE+ +
Sbjct: 1908 GGLQSKL-DAKQASKEMLEQ-DIKDLKAKQEKEVASLT-----SQILAKSKEIVGYERDL 1960

Query: 1449 EDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEE---LNVKITESVSLNKQV 1505
              L  + + E   L+ ++ +       +QK ++     + E+   L     +   LN++V
Sbjct: 1961 SSLKADYQKETTKLKNEISQKEKELAEIQKTNKKLNADIKEKEATLTASQAKVKDLNREV 2020

Query: 1506 AELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQ------KHVS 1559
             +    +++  A+  ++Q  +EN++ EI  + +E   L      S ++I+      K ++
Sbjct: 2021 QQKKDQIKDFEAQNAKLQIDIENKKAEIERIKEERRTLNTEADKSIARIEGLERKIKELT 2080

Query: 1560 FASDTK--QGRDEQLDNTMNKELLDAVPRAELDLA 1592
             +S  K  Q +  Q D     E    + + E DLA
Sbjct: 2081 GSSAEKEAQMKQYQADLAAKAETEARIKQLERDLA 2115



 Score =  132 bits (318), Expect = 1e-28
 Identities = 285/1465 (19%), Positives = 598/1465 (40%), Gaps = 157/1465 (10%)

Query: 143  DVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEK-DQIIEAKN--KATTXXXXX 199
            DV   SN++++K   LS L+ + K   T I D   +INEK  Q+++A+N  KA+      
Sbjct: 1416 DVADKSNSLQDKLEELSDLKGQQK---TRIEDFNVQINEKMAQLLKAQNELKASQASLNT 1472

Query: 200  XXXXXXXXXXXXEDT---KQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEA 256
                        E +   K+   K +E       E    +   L D + KD +   L+E 
Sbjct: 1473 TTTEYDAKIAQLEKSLKEKKDELKRKEGAATSSTEQNTVQLNKLND-DVKDKQ-KKLDEQ 1530

Query: 257  NKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSL 316
               L   + +   E + L Q ++               L K+      +++ +  EK   
Sbjct: 1531 QAELNNLKTKHQAETTDLNQTIKDTKAKLKQKETELIDLKKKH-----KDRLDTLEKTIA 1585

Query: 317  EIANMTELTKKIELLEHLNCQIR----QTNKELENKLATMGTESKAVSSPSKKGSPLISR 372
            E    T L +K   LE+L  Q R     TN+E+ +K A +           KK   L   
Sbjct: 1586 E--KQTTLAQKETELENLKAQNRTNMMNTNREIGDKTAEL----------LKKEGELRDL 1633

Query: 373  KSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKD 432
            +   + A K+     +                +E+ K +  + +L KD+ D++  I + +
Sbjct: 1634 RQKYDDAQKLADGSKEKDLAIAQYKQIIATKTSELEKAKKDVAALTKDVNDQKARIKDLE 1693

Query: 433  TXXXXXXXXXXGKDTLIAQLQLEHQQHME---GPSLIHVGTNTEDVNEIAKVQEQLKQEL 489
            +           K+T I+ L+ +++++++           T T   NEIA ++      L
Sbjct: 1694 SSVSSKRADLKKKETEISDLKRQYEENIKRLNNDLSSQKATLTAKENEIAALKSGNASRL 1753

Query: 490  NDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANK--NMIKVKSNHKLKLKQMQKTIDNF 547
            + +I++    +L +K     + +  L  ++D   K  N +  K +   KL   Q  +D+ 
Sbjct: 1754 SRDIQE-KASELAQK----NQLVANLKVQLDGLQKKQNDLLQKGSDAAKL---QADVDSL 1805

Query: 548  SK-VSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEME 606
            +K +S+  +++  L  +++ L    +EL EEK  +        S R  E    KK +  E
Sbjct: 1806 NKKISEKRQKVTELEGKVNKLD---SELAEEKARV--------SRRDREITDLKKDVSDE 1854

Query: 607  NLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEE 666
              A T  +   + + +K D+  E   + ++  EV D   D+S  ++     + +   L+ 
Sbjct: 1855 K-ARTTKRDREITDLKK-DVSDEKARVSRRDREVTDLKKDVSDEKARTTKHDNEIGGLQS 1912

Query: 667  QIDALSASKKELALVIENLKLDKE--------QLYGTIKDLENDKEDIMNKLQNYIQENM 718
            ++DA  ASK+ L   I++LK  +E        Q+    K++   + D+ +   +Y +E  
Sbjct: 1913 KLDAKQASKEMLEQDIKDLKAKQEKEVASLTSQILAKSKEIVGYERDLSSLKADYQKETT 1972

Query: 719  DLTDKLEKMSAE--KISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKS 776
             L +++ +   E  +I +   K+N + + K  T     AK+++ +  ++  + ++  +++
Sbjct: 1973 KLKNEISQKEKELAEIQKTNKKLNADIKEKEATLTASQAKVKDLNREVQQKKDQIKDFEA 2032

Query: 777  RICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRV 836
            +  +L+  I   E+++  +ER        ++E+++  +    + D+ + R+  L    + 
Sbjct: 2033 QNAKLQIDI---ENKKAEIER--------IKEERRTLNT---EADKSIARIEGLERKIKE 2078

Query: 837  VEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKY 896
            +     E E + K+ Q       E    ++    D+    N+L E   +   A  ++  Y
Sbjct: 2079 LTGSSAEKEAQMKQYQADLAAKAETEARIKQLERDLATKSNSLAEFEKKYKRANMDANNY 2138

Query: 897  QTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEY 956
            ++ L   +  + ++  E +T     K +++  E            D+ ++N++       
Sbjct: 2139 RSSLAHTQGEVAKLEEEIKTT----KGDVQYWE------------DQMIMNQE------- 2175

Query: 957  VTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKL-- 1014
                  + Q+ ++ ++ L M+V++ NK+ LE  +K +Q  +  +   ++  I++ ++L  
Sbjct: 2176 ------ETQKIQDQVDRLKMDVKDKNKI-LEDHEKEIQTLKDTATRLSQDLIHKKSELEG 2228

Query: 1015 -NALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLL- 1072
             N+ L++   ++  L Q   + +V    +V   + ++ +   +++++   +     QL+ 
Sbjct: 2229 SNSELQRVKNQVAQLTQDNKDQRV----VVDTKDGEIRKLQREVDDLNTHVMDKGDQLMK 2284

Query: 1073 ---DSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVD 1129
               D K+  +E++   ++  D    L+ET    E      +   +++ I    D      
Sbjct: 2285 RGEDIKKLRDEIKNFKKDISDHETTLEETMAEIEKL--SADNKQLTAEISSYKDKLKQSQ 2342

Query: 1130 XXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQL-ETLNTELTGH 1188
                        +K   +E+  Q+    +   A+   E+Q     I +L + ++T+    
Sbjct: 2343 TEADALNNDIKDMK-STKEKLGQDAKAKETVLAEKMKEIQGLKDSINRLNQDISTKNATL 2401

Query: 1189 DVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSA---VDQRGFEIAELWKQHLAQ 1245
            D   +E I+QLK  ++  N+  D L   V +  + ++     V  R  E+A+L K  +A 
Sbjct: 2402 DD-KREIIDQLKDDIKTANSTIDTLRKDVKDKDAILAHKTKDVVARDAELAKL-KAEIAS 2459

Query: 1246 READFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQ----VTSLQNKLQD 1301
            + A   K   E +    AFE   + L D  +   Q+   K   + Q    ++ L   + D
Sbjct: 2460 KNAALAKKTEEAK----AFEKNVQTLTDQAKGLNQDVATKTTQLAQDRATISKLNKDIFD 2515

Query: 1302 KEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQ 1361
             +  +  L+++ +     +     EI                         +TE  S   
Sbjct: 2516 LKTDVTKLKQELSTKDANLTQKAGEIGSRDAGLAKLREELRAKEAALAK--KTEEAS--- 2570

Query: 1362 MQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTH 1421
              E+++  + +E   LKK               ++  E  + +L  +L  KD+ + QKT 
Sbjct: 2571 SLEKNVKKLTDEATGLKKDVTSRDTQLAQDKDAISKLEKDIAKLNQELSTKDASLTQKTG 2630

Query: 1422 EYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESE 1481
            E      +     E +R +     K+ E+L    +S  A    ++ ++    E ++KE +
Sbjct: 2631 EVGSKNAELAKLREEIRVKETALAKKTEELKGLNQSVDA-KDTQLAQDKIKIERLEKEVK 2689

Query: 1482 ---IERVKLIEELN------VKITESVS-LNKQVAELNKALEEEVAKTNEMQTALENQEI 1531
                + VKL E++        K  E+V  L   + ELN  + +   +      A+  +E 
Sbjct: 2690 GLTADIVKLREDVAFKDKSFAKKAEAVDHLKADITELNSEVAKLKKEGTNKDAAILGKEK 2749

Query: 1532 EIVTLNDEITNLQNMVRASSSKIQK 1556
            E+V+L   + +L N  + S+   +K
Sbjct: 2750 ELVSLRKAVRDLTNQAKQSAQDSKK 2774



 Score =  130 bits (313), Expect = 4e-28
 Identities = 302/1593 (18%), Positives = 659/1593 (41%), Gaps = 146/1593 (9%)

Query: 53   KFERAQKCLENAALVSKRIKEHRKATAELLGRPFVPGISESLANTLKQKEILMEKIK-QY 111
            K    +K  ++ A ++K + + +    +L        +S   A+ LK+KE  +  +K QY
Sbjct: 1664 KTSELEKAKKDVAALTKDVNDQKARIKDLES-----SVSSKRAD-LKKKETEISDLKRQY 1717

Query: 112  KELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNALSVLQVKMKIMETT 171
            +E  KR +  +                 + G+ + LS  I+EK + L+     +  ++  
Sbjct: 1718 EENIKRLNNDLSSQKATLTAKENEIAALKSGNASRLSRDIQEKASELAQKNQLVANLKVQ 1777

Query: 172  ILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAE 231
            +  LQ+K N+   +++  + A                    + +Q++T+++     +++E
Sbjct: 1778 LDGLQKKQND---LLQKGSDAAKLQADVDSLNKKIS-----EKRQKVTELEGKVNKLDSE 1829

Query: 232  WKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXX 291
              +EK R    +  +D  I+ L++     +A   +   E + L +++             
Sbjct: 1830 LAEEKAR----VSRRDREITDLKKDVSDEKARTTKRDREITDLKKDVSDEKARVSRRDRE 1885

Query: 292  XXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLAT 351
               L K   +          E G L+    ++L  K    E L   I+    + E ++A+
Sbjct: 1886 VTDLKKDVSDEKARTTKHDNEIGGLQ----SKLDAKQASKEMLEQDIKDLKAKQEKEVAS 1941

Query: 352  MGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLE 411
            + ++  A      K   ++  +      S +K+ + + +++  N+ + K+    E+A+++
Sbjct: 1942 LTSQILA------KSKEIVGYE---RDLSSLKADYQKETTKLKNEISQKE---KELAEIQ 1989

Query: 412  MVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTN 471
               + LN D+ +KE  ++               K   I   + ++ +       I +   
Sbjct: 1990 KTNKKLNADIKEKEATLTASQAKVKDLNREVQQKKDQIKDFEAQNAKLQ-----IDIENK 2044

Query: 472  TEDVNEIAKVQEQLKQELNDEIKDVN-----VKDLIEKLKSAEEQITQLNDEIDAANKNM 526
              ++  I + +  L  E +  I  +      +K+L       E Q+ Q   ++ A  +  
Sbjct: 2045 KAEIERIKEERRTLNTEADKSIARIEGLERKIKELTGSSAEKEAQMKQYQADLAAKAETE 2104

Query: 527  IKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEE----KGNLQ 582
             ++K   +    +     +   K   +N +       L H   +VA+LEEE    KG++Q
Sbjct: 2105 ARIKQLERDLATKSNSLAEFEKKYKRANMDANNYRSSLAHTQGEVAKLEEEIKTTKGDVQ 2164

Query: 583  LH----LVDYDSGRMIESDVYKKMIEMEN---LAETRLKAISLLESQKFDLVQ------- 628
                  +++ +  + I+  V +  +++++   + E   K I  L+     L Q       
Sbjct: 2165 YWEDQMIMNQEETQKIQDQVDRLKMDVKDKNKILEDHEKEIQTLKDTATRLSQDLIHKKS 2224

Query: 629  ELHILQQKYDEVEDKLADISQLQSDQ-VCSEIKSVH---LEEQIDALSA----SKKELAL 680
            EL     +   V++++A ++Q   DQ V  + K      L+ ++D L+        +L  
Sbjct: 2225 ELEGSNSELQRVKNQVAQLTQDNKDQRVVVDTKDGEIRKLQREVDDLNTHVMDKGDQLMK 2284

Query: 681  VIENLKLDKEQLYGTIKDL---ENDKEDIMNKLQNYIQENMDLTDKLEKMSAE-KISELL 736
              E++K  ++++    KD+   E   E+ M +++    +N  LT ++     + K S+  
Sbjct: 2285 RGEDIKKLRDEIKNFKKDISDHETTLEETMAEIEKLSADNKQLTAEISSYKDKLKQSQTE 2344

Query: 737  AK-INHE--EQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESI----AVME 789
            A  +N++  +    + + G DAK +E  L  E ++ E+   K  I RL + I    A ++
Sbjct: 2345 ADALNNDIKDMKSTKEKLGQDAKAKETVL-AEKMK-EIQGLKDSINRLNQDISTKNATLD 2402

Query: 790  DRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENK 849
            D+R  +++  D + +          +   ++  L ++   ++  D  + K   EI  +N 
Sbjct: 2403 DKREIIDQLKDDIKTANSTIDTLRKDVKDKDAILAHKTKDVVARDAELAKLKAEIASKNA 2462

Query: 850  ELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESEST--KYQTQLRDLESNL 907
             L KK +      +N+Q +L+D  +  N  V     T LA+  +T  K    + DL++++
Sbjct: 2463 ALAKKTEEAKAFEKNVQ-TLTDQAKGLNQDVA-TKTTQLAQDRATISKLNKDIFDLKTDV 2520

Query: 908  KRITHEHQTL---IVQKKKEIEDLEI---EFNTQI---ESAIRDKKVLNEKYEKNIEYVT 958
             ++  E  T    + QK  EI   +    +   ++   E+A+  K       EKN++ +T
Sbjct: 2521 TKLKQELSTKDANLTQKAGEIGSRDAGLAKLREELRAKEAALAKKTEEASSLEKNVKKLT 2580

Query: 959  QLEAQLQ-EYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNAL 1017
                 L+ +  +    L  + + ++K+  + I K  Q+  T+    T++   E+   NA 
Sbjct: 2581 DEATGLKKDVTSRDTQLAQDKDAISKLEKD-IAKLNQELSTKDASLTQK-TGEVGSKNAE 2638

Query: 1018 LKQKDEEI----IALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLD 1073
            L +  EEI     AL +K    +    S V   +++LAQ   K+E +E+E++ ++  ++ 
Sbjct: 2639 LAKLREEIRVKETALAKKTEELKGLNQS-VDAKDTQLAQDKIKIERLEKEVKGLTADIVK 2697

Query: 1074 SKQHNEELQILVREQDDQIKELKE--TKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXX 1131
             ++          ++ + +  LK   T+L  E+   K EG    + I     +  ++   
Sbjct: 2698 LREDVAFKDKSFAKKAEAVDHLKADITELNSEVAKLKKEGTNKDAAILGKEKELVSLRKA 2757

Query: 1132 XXXXXXXX--XXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQL-ETLN-TELTG 1187
                           ++  E +  R  L ++  K   ELQ+   K+    E LN T  T 
Sbjct: 2758 VRDLTNQAKQSAQDSKKSAEDLANRDALLKEKEKKIFELQQEIQKVKDTAEELNQTTKTR 2817

Query: 1188 HDVVNQ--EQINQLKSKLEQLNTENDNLLSTVAELRSSIS---SAVDQRGFEIAELWKQ- 1241
               ++Q  E++ +L+ +++QL  E ++L      L  +I+   S+++Q+  EI+ L K+ 
Sbjct: 2818 DSTLSQKNEELRKLREQIKQLEDEANSLKMDKETLGRTINTRDSSLEQKEQEISGLEKEI 2877

Query: 1242 -HLAQREADFQKTEHELRVQLSAFESKYEQL---LDSVQSSTQEETNKIVTMEQVTSLQN 1297
              L+++ A+  + + +L   + A ++   Q    +D ++ S +    K   + ++ + Q+
Sbjct: 2878 KRLSEQAANLTQEKVDLGQIVGARDASLLQANKDIDGLKGSIKILEEKAAELSKLNAGQD 2937

Query: 1298 K-LQDKEEHLRNLQEKYADVINQIEILRSE---IEDEKVAFXXXXXXXXXXXXXXXXDLR 1353
            + + +K+  L+   E   ++   ++ L ++   + +EK                   D++
Sbjct: 2938 QTIGEKDASLQKANEDIDNLKGSVQKLENKAATLAEEKAQMGQTIGAHETSLLKKDEDIK 2997

Query: 1354 TENQSYKQMQ-EQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQ---L 1409
                + +++  E + L    EN  L                 + + E  + +L  +   L
Sbjct: 2998 KLTANIQRLTAEANDLKKGIEN--LTGDIAIQNRALAQKEKDIQNMEKTIQDLNTEVARL 3055

Query: 1410 ELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIE-------DLTYEKESELAIL 1462
            +   +E  QKT     TLT +ND+   +  Q+ +    +        DL     S+  +L
Sbjct: 3056 KTNAAEHNQKTIAKDATLTAKNDQISKLNDQIKQLRAEVTKLKSDAADLNQATTSKDIVL 3115

Query: 1463 RLKMHE-NANHYETMQKESEIER-----VKLIEELNVKITESVS-LNKQVAELNKALEEE 1515
              +M E N    E ++    ++      ++  +E+N ++ E+V  L  +  +L K   + 
Sbjct: 3116 AQRMEEINGLRNEMVELNKALDTRDTTFLQNTDEIN-RLKENVRRLGDETTKLKKDTVKL 3174

Query: 1516 VAKTNEMQTALENQEIEIVTLNDEITNLQNMVR 1548
               +   +  ++ ++ EI  LND I NLQ  ++
Sbjct: 3175 KEDSKSWEETVKQRQTEINKLNDNIKNLQEEIK 3207



 Score =  119 bits (287), Expect = 6e-25
 Identities = 257/1310 (19%), Positives = 518/1310 (39%), Gaps = 112/1310 (8%)

Query: 328  IELLEHLNCQIRQTNKEL-ENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPW 386
            +E+ +++      T + L + + A    E+ A  S ++  S  I + +  N   K +   
Sbjct: 602  LEVFDNILNLYEDTEQRLVQTEEAKDKAEAAAKESATRSRSETIQKLTSENNKLKEQRDE 661

Query: 387  SQLSSETLNQDTDKK--INKNEIAKLEMVI-QSLNKDLVDKEYVISEKDTXXXXXXXXXX 443
             +  ++   Q   KK  +   E     + + Q   KD  D+    SEK+           
Sbjct: 662  QKRKADAFYQKLKKKGWLEPTEDPSASLALDQKSLKDQQDRWE--SEKNALNQKITNLNK 719

Query: 444  GKDTLIAQLQLEHQQHMEGPSLIHVGTNTE-DVNEIAKVQEQLKQELNDEIK-DVNVKDL 501
              +     L+      +E  SL+ +    E D+  + +    LKQ+L  +     ++KD 
Sbjct: 720  SIEEANVALKDMKLMQVERDSLVDLQQRQEGDIKSLNQQVLDLKQKLASKASAGADLKD- 778

Query: 502  IEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLT 561
            I+ L+   + +      + A  + + +  S  K +L++++ T+ N +    S K  + L 
Sbjct: 779  IQSLRLENKSLEDQRQRVQAEKEVLQQQLSQTKARLEKVETTLKNTA----SQK--MDLE 832

Query: 562  EELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLES 621
             + +  S+    LEEE   L+   VD          + +   E  N+AE+  +   L++ 
Sbjct: 833  TQRNEWSKAKKVLEEEISRLKKE-VDLARKNSAAPTIVEIKPE-PNIAESITRVEQLMKE 890

Query: 622  QKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALV 681
            QK     +L +  +  D V+  +A +   Q  +     + V + E I  L+   KE    
Sbjct: 891  QK----PQLPLTAR--DFVQGLVAKLKDAQGHKDLDASEDV-IRECIGLLNRVLKEPVFD 943

Query: 682  IENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKIS-ELLAKIN 740
                + DKE L    + L+N+  + + K +   +++  L   ++K   EK S E   K++
Sbjct: 944  ----EKDKEML----QTLQNELNEALRKGKEDREQSAQLQSIIDKYEGEKESLEKEVKVH 995

Query: 741  HEEQSKIQTQF-----GIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSL 795
             +E  K++ +       +  K QERD+  E+ E ++    +   +    + V      + 
Sbjct: 996  KDEIKKLKQEITEKKTSLANKQQERDMLKESYEEQIKNLNADHKKAAAELKVKHQNELTQ 1055

Query: 796  ERKADQLG--SYLQE----KQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENK 849
             RK   L   + LQ+    +Q+  SE    + +     A L       +K + + E +  
Sbjct: 1056 LRKDGDLKETNLLQKLDTLRQQNESERNRLQADYAAEKAKLTKDIEAQKKLVAQKEKDLA 1115

Query: 850  ELQ-KKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLR--DLESN 906
            EL+ KK + + E  Q   + ++ ++      +E+     L E+E  + Q Q R  +LES 
Sbjct: 1116 ELKSKKEKEIKELTQKKDVEIATLKSTKQVDMEQLKNRHLQETEILRKQHQSRVGELESE 1175

Query: 907  LKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKN--IEYVTQLEAQL 964
            +  I  +++  + +  +     +     Q E+ + + K   E+ +K   +++ T++E+  
Sbjct: 1176 IATIKEKYKKDLDELSRNNTSQDAIKLKQHENELANFKAKYEQEKKQLAVQHKTEMESLT 1235

Query: 965  QEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEE 1024
              Y    +      E +  ++ EL DK     +T   +Y EQ      +L+ L      +
Sbjct: 1236 DRYHEKEKLATQYQERVQALSAELADK-----KTALAEYKEQLSASKAQLDKLKADHGVK 1290

Query: 1025 IIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQ---HNEEL 1081
            +  L  K+ +       + +DYE  L++  TK +  E  + +V  Q    K    HNE++
Sbjct: 1291 VDELQAKLKS---EVAKVTADYEGNLSELRTKHQG-EVNVLKVHHQDEIKKLTAGHNEKI 1346

Query: 1082 QILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXX 1141
            + L    +D   ELK+ +  F+      EG +  +T++   DD ++              
Sbjct: 1347 RNLEHRINDLKAELKQDRAEFDKKKALLEGEV--ATLQGKVDDKSS---KLSSKEAEFNE 1401

Query: 1142 LKVQEEEEFIQERSVLQEQSAKLNTELQECYT----KIIQLETLNTELTGHDVVNQEQIN 1197
            LK   E +  + R  + ++S  L  +L+E       +  ++E  N ++        +  N
Sbjct: 1402 LKKLNEAQIAELRKDVADKSNSLQDKLEELSDLKGQQKTRIEDFNVQINEKMAQLLKAQN 1461

Query: 1198 QLKSKLEQLNTENDNLLSTVAELRSSISSAVDQ---RGFEIAELWKQHLAQREA------ 1248
            +LK+    LNT      + +A+L  S+    D+   +        +Q+  Q         
Sbjct: 1462 ELKASQASLNTTTTEYDAKIAQLEKSLKEKKDELKRKEGAATSSTEQNTVQLNKLNDDVK 1521

Query: 1249 DFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTME-QVTSLQNKLQDK----E 1303
            D QK   E + +L+  ++K++     +  + ++   K+   E ++  L+ K +D+    E
Sbjct: 1522 DKQKKLDEQQAELNNLKTKHQAETTDLNQTIKDTKAKLKQKETELIDLKKKHKDRLDTLE 1581

Query: 1304 EHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQ 1363
            + +   Q   A    ++E L+++     +                  +LR   Q Y   Q
Sbjct: 1582 KTIAEKQTTLAQKETELENLKAQNRTNMMNTNREIGDKTAELLKKEGELRDLRQKYDDAQ 1641

Query: 1364 E----------------QSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTH 1407
            +                Q I     E  + KK              R+ D E+ V     
Sbjct: 1642 KLADGSKEKDLAIAQYKQIIATKTSELEKAKKDVAALTKDVNDQKARIKDLESSVSSKRA 1701

Query: 1408 QLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLT-----------YEKE 1456
             L+ K++EI     +Y   + + N++  + +  L   E  I  L             EK 
Sbjct: 1702 DLKKKETEISDLKRQYEENIKRLNNDLSSQKATLTAKENEIAALKSGNASRLSRDIQEKA 1761

Query: 1457 SELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEV 1516
            SELA     +       + +QK+      K  +   ++  +  SLNK+++E  + + E  
Sbjct: 1762 SELAQKNQLVANLKVQLDGLQKKQNDLLQKGSDAAKLQ-ADVDSLNKKISEKRQKVTELE 1820

Query: 1517 AKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQ 1566
             K N++ + L  ++  +   + EIT+L+  V    ++  K     +D K+
Sbjct: 1821 GKVNKLDSELAEEKARVSRRDREITDLKKDVSDEKARTTKRDREITDLKK 1870



 Score =  111 bits (266), Expect = 2e-22
 Identities = 295/1610 (18%), Positives = 630/1610 (39%), Gaps = 170/1610 (10%)

Query: 57   AQKCLENAALVSKRIKEHRKATAELLGRPFVPGISESLANTLKQKEILMEKIKQYKELSK 116
            A K   +   ++K+I E R+   EL G+  V  +   LA   ++K  +  + ++  +L K
Sbjct: 1795 AAKLQADVDSLNKKISEKRQKVTELEGK--VNKLDSELA---EEKARVSRRDREITDLKK 1849

Query: 117  RSSTTIVRXXXXXXXXXXXXX--XXQLGDVTHLSNTIKEKDNALSVLQVKMKIMETTILD 174
              S    R                 +   V+     + +    +S  + +    +  I  
Sbjct: 1850 DVSDEKARTTKRDREITDLKKDVSDEKARVSRRDREVTDLKKDVSDEKARTTKHDNEIGG 1909

Query: 175  LQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKD 234
            LQ K++ K    E   +                        +++   + +  +++A+++ 
Sbjct: 1910 LQSKLDAKQASKEMLEQDIKDLKAKQEKEVASLTSQILAKSKEIVGYERDLSSLKADYQK 1969

Query: 235  EKQRLLKDIESKDVRISSLEEANKLLEA--ARFEISLEHSK-----LAQELEQXXXXXXX 287
            E  +L  +I  K+  ++ +++ NK L A     E +L  S+     L +E++Q       
Sbjct: 1970 ETTKLKNEISQKEKELAEIQKTNKKLNADIKEKEATLTASQAKVKDLNREVQQKKDQIKD 2029

Query: 288  XXXXXXXLA------KQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLE----HLNCQ 337
                   L       K  IE   EE+  +  +    IA +  L +KI+ L         Q
Sbjct: 2030 FEAQNAKLQIDIENKKAEIERIKEERRTLNTEADKSIARIEGLERKIKELTGSSAEKEAQ 2089

Query: 338  IRQTNKELENKLAT----------MGTESKAVSSPSKKGSPL-ISRKSGRNTASKMKSPW 386
            ++Q   +L  K  T          + T+S +++   KK     +   + R++ +  +   
Sbjct: 2090 MKQYQADLAAKAETEARIKQLERDLATKSNSLAEFEKKYKRANMDANNYRSSLAHTQGEV 2149

Query: 387  SQLSSE--TLNQDT----DKKI-NKNEIAKLEMVIQSLNKDLVDKEYVIS--EKDTXXXX 437
            ++L  E  T   D     D+ I N+ E  K++  +  L  D+ DK  ++   EK+     
Sbjct: 2150 AKLEEEIKTTKGDVQYWEDQMIMNQEETQKIQDQVDRLKMDVKDKNKILEDHEKEIQTLK 2209

Query: 438  XXXXXXGKDTLIAQLQLEHQ----QHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEI 493
                   +D +  + +LE      Q ++   +  +  + +D   +   ++   ++L  E+
Sbjct: 2210 DTATRLSQDLIHKKSELEGSNSELQRVKN-QVAQLTQDNKDQRVVVDTKDGEIRKLQREV 2268

Query: 494  KDVN--VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVS 551
             D+N  V D  ++L    E I +L DEI    KN  K  S+H+  L++   T+    K+S
Sbjct: 2269 DDLNTHVMDKGDQLMKRGEDIKKLRDEI----KNFKKDISDHETTLEE---TMAEIEKLS 2321

Query: 552  DSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDS--------GRMIESDVYKKMI 603
              NK+   LT E+     K+ + + E   L   + D  S         +  E+ + +KM 
Sbjct: 2322 ADNKQ---LTAEISSYKDKLKQSQTEADALNNDIKDMKSTKEKLGQDAKAKETVLAEKMK 2378

Query: 604  EMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVH 663
            E++ L ++  +    + ++   L  +  I+ Q  D+++   + I  L+ D    +    H
Sbjct: 2379 EIQGLKDSINRLNQDISTKNATLDDKREIIDQLKDDIKTANSTIDTLRKDVKDKDAILAH 2438

Query: 664  LEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDK 723
              + + A  A   +L   I +      +     K  E + + + ++ +   Q+    T +
Sbjct: 2439 KTKDVVARDAELAKLKAEIASKNAALAKKTEEAKAFEKNVQTLTDQAKGLNQDVATKTTQ 2498

Query: 724  L--EKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRL 781
            L  ++ +  K+++ +  +  +     Q     DA + ++   I + ++ L+K +  +   
Sbjct: 2499 LAQDRATISKLNKDIFDLKTDVTKLKQELSTKDANLTQKAGEIGSRDAGLAKLREELRAK 2558

Query: 782  EESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQL 841
            E ++A   +   SLE+   +L     E      + T ++ +L      +   ++ + K  
Sbjct: 2559 EAALAKKTEEASSLEKNVKKL---TDEATGLKKDVTSRDTQLAQDKDAISKLEKDIAKLN 2615

Query: 842  LEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANR-------TDLAESEST 894
             E+  ++  L +K   +  +N  L     +++    AL +K           D  +++  
Sbjct: 2616 QELSTKDASLTQKTGEVGSKNAELAKLREEIRVKETALAKKTEELKGLNQSVDAKDTQLA 2675

Query: 895  KYQTQLRDLESNLKRITHEHQTL----------IVQKKKEIEDLEI---EFNTQI----- 936
            + + ++  LE  +K +T +   L            +K + ++ L+    E N+++     
Sbjct: 2676 QDKIKIERLEKEVKGLTADIVKLREDVAFKDKSFAKKAEAVDHLKADITELNSEVAKLKK 2735

Query: 937  ESAIRDKKVLNEKYEKNIEYVTQLEAQL-QEYKNNIENLNMNVEELNKMNLELIDKHVQ- 994
            E   +D  +L +  EK +  + +    L  + K + ++   + E+L   +  L +K  + 
Sbjct: 2736 EGTNKDAAILGK--EKELVSLRKAVRDLTNQAKQSAQDSKKSAEDLANRDALLKEKEKKI 2793

Query: 995  ---KQQTQSPDYTEQYINEINKL-NALLKQKDEEIIALNQKINNAQVSYMSMVSDYE--- 1047
               +Q+ Q    T + +N+  K  ++ L QK+EE+  L ++I   +    S+  D E   
Sbjct: 2794 FELQQEIQKVKDTAEELNQTTKTRDSTLSQKNEELRKLREQIKQLEDEANSLKMDKETLG 2853

Query: 1048 -------SKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQD----------D 1090
                   S L Q   ++  +E+E++R+S+Q  +  Q   +L  +V  +D          D
Sbjct: 2854 RTINTRDSSLEQKEQEISGLEKEIKRLSEQAANLTQEKVDLGQIVGARDASLLQANKDID 2913

Query: 1091 QIK---ELKETKLTFEMNIPKTEGMII---SSTIEPMSDDANNVDXXXXXXXXXXXXL-- 1142
             +K   ++ E K      +   +   I    ++++  ++D +N+             L  
Sbjct: 2914 GLKGSIKILEEKAAELSKLNAGQDQTIGEKDASLQKANEDIDNLKGSVQKLENKAATLAE 2973

Query: 1143 -KVQEEEEF-IQERSVLQ--EQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQ 1198
             K Q  +     E S+L+  E   KL   +Q    +   L+     LTG   +    + Q
Sbjct: 2974 EKAQMGQTIGAHETSLLKKDEDIKKLTANIQRLTAEANDLKKGIENLTGDIAIQNRALAQ 3033

Query: 1199 LKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELR 1258
             +  ++ +     +L + VA L+   ++A +     IA+     L  +     K   +++
Sbjct: 3034 KEKDIQNMEKTIQDLNTEVARLK---TNAAEHNQKTIAK--DATLTAKNDQISKLNDQIK 3088

Query: 1259 VQLSAFESKYE-QLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVI 1317
             QL A  +K +    D  Q++T ++      ME++  L+N++ +  + L      +    
Sbjct: 3089 -QLRAEVTKLKSDAADLNQATTSKDIVLAQRMEEINGLRNEMVELNKALDTRDTTFLQNT 3147

Query: 1318 NQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQL 1377
            ++I  L+  +                       D ++  ++ KQ Q + I  +N+    L
Sbjct: 3148 DEINRLKENVR----RLGDETTKLKKDTVKLKEDSKSWEETVKQRQTE-INKLNDNIKNL 3202

Query: 1378 KKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENV 1437
            ++               +N  + +++ L   L  KD++           L  R+ E    
Sbjct: 3203 QEEIKRKEALLATRQGEINALKDEIVGLKKDLAEKDAQ-----------LKSRDGELGKF 3251

Query: 1438 RQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITE 1497
            R+ +   E  +E L    E E   LR K+          ++  ++   K++E  N +   
Sbjct: 3252 RKSIAAKETALERL----EKEKTALREKVEHLEGEVGRRRRSLDLRADKILELTNSESAA 3307

Query: 1498 SVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMV 1547
             + L+KQ A  NK+LEE       ++     +   +  L DE+T L   +
Sbjct: 3308 RLDLDKQRAR-NKSLEE---TNTGLRNRAAKEGGSLGRLGDEVTKLSRQL 3353



 Score =  108 bits (259), Expect = 1e-21
 Identities = 271/1416 (19%), Positives = 557/1416 (39%), Gaps = 121/1416 (8%)

Query: 144  VTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKAT--TXXXXXXX 201
            V  L   +K+K+  L   + +++ ++ T   L + +  K   +E  N             
Sbjct: 2184 VDRLKMDVKDKNKILEDHEKEIQTLKDTATRLSQDLIHKKSELEGSNSELQRVKNQVAQL 2243

Query: 202  XXXXXXXXXXEDTKQ-QMTKMQENFIAMEAEWKDEKQRLLK---DIESKDVRISSLEEAN 257
                       DTK  ++ K+Q     +     D+  +L+K   DI+     I + ++  
Sbjct: 2244 TQDNKDQRVVVDTKDGEIRKLQREVDDLNTHVMDKGDQLMKRGEDIKKLRDEIKNFKKDI 2303

Query: 258  KLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQS--IEPSCEEKTEIEEK-G 314
               E    E   E  KL+ + +Q                 ++  +    ++    +EK G
Sbjct: 2304 SDHETTLEETMAEIEKLSADNKQLTAEISSYKDKLKQSQTEADALNNDIKDMKSTKEKLG 2363

Query: 315  SLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKS 374
                A  T L +K++ ++ L   I + N+++  K AT+  + + +             K+
Sbjct: 2364 QDAKAKETVLAEKMKEIQGLKDSINRLNQDISTKNATLDDKREIIDQLKD------DIKT 2417

Query: 375  GRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDK--EYVISEKD 432
              +T   ++       +   ++  D      E+AKL+  I S N  L  K  E    EK+
Sbjct: 2418 ANSTIDTLRKDVKDKDAILAHKTKDVVARDAELAKLKAEIASKNAALAKKTEEAKAFEKN 2477

Query: 433  TXXXXXXXXXXGKDTLIAQLQLEHQQ---HMEGPSLIHVGTN-TEDVNEIAKVQEQLKQE 488
                        +D      QL   +         +  + T+ T+   E++     L Q+
Sbjct: 2478 VQTLTDQAKGLNQDVATKTTQLAQDRATISKLNKDIFDLKTDVTKLKQELSTKDANLTQK 2537

Query: 489  LND-EIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNF 547
              +   +D  +  L E+L++ E  + +  +E  +  KN+ K+        K +       
Sbjct: 2538 AGEIGSRDAGLAKLREELRAKEAALAKKTEEASSLEKNVKKLTDEATGLKKDVTSRDTQL 2597

Query: 548  SKVSDS----NKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDY-DSGRMIESDVYKKM 602
            ++  D+     K+I +L +EL      + +   E G+    L    +  R+ E+ + KK 
Sbjct: 2598 AQDKDAISKLEKDIAKLNQELSTKDASLTQKTGEVGSKNAELAKLREEIRVKETALAKKT 2657

Query: 603  IEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSV 662
             E++ L ++       ++++   L Q+   +++   EV+   ADI +L+ D    +    
Sbjct: 2658 EELKGLNQS-------VDAKDTQLAQDKIKIERLEKEVKGLTADIVKLREDVAFKDKSFA 2710

Query: 663  HLEEQIDALSASKKELALVIENLKLDKEQ----LYGTIKDLENDKE---DIMNKLQNYIQ 715
               E +D L A   EL   +  LK +       + G  K+L + ++   D+ N+ +   Q
Sbjct: 2711 KKAEAVDHLKADITELNSEVAKLKKEGTNKDAAILGKEKELVSLRKAVRDLTNQAKQSAQ 2770

Query: 716  ENMDLTDKLEKMSA--EKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSK 773
            ++    + L    A  ++  + + ++  E Q    T   ++   + RD  +     EL K
Sbjct: 2771 DSKKSAEDLANRDALLKEKEKKIFELQQEIQKVKDTAEELNQTTKTRDSTLSQKNEELRK 2830

Query: 774  YKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYS----EYTIQEDELVNRLAV 829
             + +I +LE+    ++  + +L R  +   S L++K++  S    E     ++  N    
Sbjct: 2831 LREQIKQLEDEANSLKMDKETLGRTINTRDSSLEQKEQEISGLEKEIKRLSEQAANLTQE 2890

Query: 830  LMDHDRVVEKQLLEIEHENKELQK-KNQILLEENQNLQISLSDMQQHY-----NALVEKA 883
             +D  ++V  +   +   NK++   K  I + E +  ++S  +  Q       +A ++KA
Sbjct: 2891 KVDLGQIVGARDASLLQANKDIDGLKGSIKILEEKAAELSKLNAGQDQTIGEKDASLQKA 2950

Query: 884  NRT-DLAESESTKYQTQ---LRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESA 939
            N   D  +    K + +   L + ++ + +    H+T +++K ++I+ L      ++ + 
Sbjct: 2951 NEDIDNLKGSVQKLENKAATLAEEKAQMGQTIGAHETSLLKKDEDIKKLTANIQ-RLTAE 3009

Query: 940  IRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQ-KQQT 998
              D K   E    +I    +  AQ ++   +I+N+   +++LN     L     +  Q+T
Sbjct: 3010 ANDLKKGIENLTGDIAIQNRALAQKEK---DIQNMEKTIQDLNTEVARLKTNAAEHNQKT 3066

Query: 999  QSPDYTEQYINE-INKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKL 1057
             + D T    N+ I+KLN  +KQ   E+  L  K + A ++  +   D    LAQ   ++
Sbjct: 3067 IAKDATLTAKNDQISKLNDQIKQLRAEVTKL--KSDAADLNQATTSKDIV--LAQRMEEI 3122

Query: 1058 ENMEEEMQRVSKQLLDSK-----QHNEELQIL---VREQDDQIKELKETKLTFEMNIPKT 1109
              +  EM  ++K L D++     Q+ +E+  L   VR   D+  +LK+  +  + +    
Sbjct: 3123 NGLRNEMVELNKAL-DTRDTTFLQNTDEINRLKENVRRLGDETTKLKKDTVKLKEDSKSW 3181

Query: 1110 EGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQ 1169
            E  +     E ++   +N+             L  ++ E      + L+++   L  +L 
Sbjct: 3182 EETVKQRQTE-INKLNDNIKNLQEEIKRKEALLATRQGEI-----NALKDEIVGLKKDLA 3235

Query: 1170 ECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISS--- 1226
            E   K  QL++ + EL       ++ I   ++ LE+L  E   L   V  L   +     
Sbjct: 3236 E---KDAQLKSRDGELGKF----RKSIAAKETALERLEKEKTALREKVEHLEGEVGRRRR 3288

Query: 1227 AVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKI 1286
            ++D R  +I EL     A R  D  K          A     E+    +++   +E   +
Sbjct: 3289 SLDLRADKILELTNSESAAR-LDLDKQR--------ARNKSLEETNTGLRNRAAKEGGSL 3339

Query: 1287 VTM-EQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXX 1345
              + ++VT L  +L +KE  L +L+++   +   I  L   +  E               
Sbjct: 3340 GRLGDEVTKLSRQLLEKENDLASLRDECDGLQTDIHNLTRALAAE----GANVSQRDEQI 3395

Query: 1346 XXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLEL 1405
                 +L T   +    Q      IN   +QL ++                +        
Sbjct: 3396 ALLKQELTTRQAALDAKQAA----INTLESQLTEAQQAYDILASSNTTSQEELARSAAAT 3451

Query: 1406 THQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEK-ESELAILRL 1464
              +L   ++EI     E    +T  N++    + Q+ + EKRI+ L  E   SE  + R+
Sbjct: 3452 QARLLACEAEIASLRSE----ITNLNEDITAKKTQIADNEKRIDTLLREAGTSEAQLARM 3507

Query: 1465 KMHENANHYETMQKESEIERVKLIEELNVKITESVS 1500
            KM         +Q+E E ++ +L++E   ++ ++ +
Sbjct: 3508 KM-----TIAELQEEQENQQ-RLLDEYQSRLAQAAT 3537



 Score = 37.1 bits (82), Expect = 4.0
 Identities = 98/549 (17%), Positives = 216/549 (39%), Gaps = 47/549 (8%)

Query: 143  DVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXX 202
            D+ +L  ++++ +N  + L  +   M  TI   +  + +KD+ I    K  T        
Sbjct: 2953 DIDNLKGSVQKLENKAATLAEEKAQMGQTIGAHETSLLKKDEDI----KKLTANIQRLTA 3008

Query: 203  XXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRI-SSLEEANKLLE 261
                     E+    +  +Q   +A + +     ++ ++D+ ++  R+ ++  E N+   
Sbjct: 3009 EANDLKKGIENLTGDIA-IQNRALAQKEKDIQNMEKTIQDLNTEVARLKTNAAEHNQKTI 3067

Query: 262  AARFEISLEH---SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEI 318
            A    ++ ++   SKL  +++Q              L + +          +EE   L  
Sbjct: 3068 AKDATLTAKNDQISKLNDQIKQLRAEVTKLKSDAADLNQATTSKDIVLAQRMEEINGLR- 3126

Query: 319  ANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNT 378
              M EL K ++  +    Q       L+  +  +G E+  +   + K       KS   T
Sbjct: 3127 NEMVELNKALDTRDTTFLQNTDEINRLKENVRRLGDETTKLKKDTVKLKE--DSKSWEET 3184

Query: 379  ASKMKSPWSQLSS--ETLNQDTDKK-----INKNEIAKLEMVIQSLNKDLVDKEYVISEK 431
              + ++  ++L+   + L ++  +K       + EI  L+  I  L KDL +K+  +  +
Sbjct: 3185 VKQRQTEINKLNDNIKNLQEEIKRKEALLATRQGEINALKDEIVGLKKDLAEKDAQLKSR 3244

Query: 432  DTXXXXXXXXXXGKDTLIAQLQLEHQ------QHMEGPSLIHVGTNTEDVNEIAKVQEQL 485
            D            K+T + +L+ E        +H+EG     VG     ++   +  + L
Sbjct: 3245 DGELGKFRKSIAAKETALERLEKEKTALREKVEHLEG----EVGRRRRSLD--LRADKIL 3298

Query: 486  KQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTID 545
            +   ++    +++     + KS EE  T L +       ++ ++        +Q+ +  +
Sbjct: 3299 ELTNSESAARLDLDKQRARNKSLEETNTGLRNRAAKEGGSLGRLGDEVTKLSRQLLEKEN 3358

Query: 546  NFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEM 605
            + + + D   E   L  ++H+L++ +A    E  N+        S R  +  + K+ +  
Sbjct: 3359 DLASLRD---ECDGLQTDIHNLTRALA---AEGANV--------SQRDEQIALLKQELTT 3404

Query: 606  ENLA-ETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLA-DISQLQSDQVCSEIKSVH 663
               A + +  AI+ LESQ  +  Q   IL       +++LA   +  Q+  +  E +   
Sbjct: 3405 RQAALDAKQAAINTLESQLTEAQQAYDILASSNTTSQEELARSAAATQARLLACEAEIAS 3464

Query: 664  LEEQIDALS 672
            L  +I  L+
Sbjct: 3465 LRSEITNLN 3473


>UniRef50_Q8MSS1 Cluster: Protein lava lamp; n=1; Drosophila
            melanogaster|Rep: Protein lava lamp - Drosophila
            melanogaster (Fruit fly)
          Length = 2779

 Score =  135 bits (327), Expect = 8e-30
 Identities = 286/1545 (18%), Positives = 623/1545 (40%), Gaps = 117/1545 (7%)

Query: 99   KQKEILMEKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNAL 158
            + K  + + ++  K L ++ +    R                 GDV+ L  +  EK    
Sbjct: 87   RHKSSMSDSMESLKTLGQKLTVLKTRSGDSSTPLVSPTKDSDPGDVSLLQTSGSEK---- 142

Query: 159  SVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQM 218
             +L +  +  +   L  Q K +    ++  K+                       +   +
Sbjct: 143  -LLMLTQRTEQNRALLEQRKRDLAKSLLSVKSNIGHQTTAELGSSMTDLRHAASVSNPPV 201

Query: 219  TKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISL-EHSKLAQE 277
            ++   + + +EA+ ++        +    ++++ L++  +  E       L + +KL + 
Sbjct: 202  SR-HRSALDLEAQGQEAVDESRVKLLRSRMKLTELKQGRQEQELNELRTELAKRAKLIER 260

Query: 278  LE-QXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNC 336
            LE                L +  +  + E+  +++E   L+   +  L +++  LE++N 
Sbjct: 261  LELSGAELQRTLTQRNEELEQLRVVQAEEDSLKVQENSRLQ-GEVLVLRERLAELENVND 319

Query: 337  QIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQ 396
             +  T  EL+ +L T     + +    ++       K+ R+  S+     +Q+S+E   Q
Sbjct: 320  LLETTRCELQEELTTARERQRNLELEQEQ------EKASRSPQSEAAHTDAQVSAELAKQ 373

Query: 397  DTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQL-QLE 455
              +     N++A L+   + L + +  +  +   + T           + T+ AQL +L+
Sbjct: 374  LQELT---NQLADLQATNEELRQQVAAQAKL---QVTDEIVSQRLEELEATIAAQLLELQ 427

Query: 456  HQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQEL--NDEIKDVNVKDLIEKL---KSAEE 510
             Q+         +   T ++N +      L+++L  +   K + ++D  E     K  +E
Sbjct: 428  EQKSAMAAQNEELAEKTTELNVLNVNLRLLEEKLAQSSRSKPLFLEDHSEDSAASKQMQE 487

Query: 511  QITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQK 570
             + QL  ++D  NK  IK+K    LK KQ +K +  F    D  +++  L  +   L Q+
Sbjct: 488  DLQQLKLKLDETNKANIKLK----LKCKQAEKKLQKFQS-QDGQQQLASLLADNEELQQR 542

Query: 571  VAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQEL 630
            +A LE+EKG  QL         M E D   +    E+    +L+ I LLE QK +L Q L
Sbjct: 543  IAVLEDEKGQWQL-------ANMQEDDRQPEQ-STESNNPLQLETIRLLEEQKLELQQAL 594

Query: 631  HILQQKYDEVED-KLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDK 689
              L       E  ++ +   L+             +EQ          ++ + +  + ++
Sbjct: 595  EALLSSSSSAESIEIVERHHLECLGQRRPASEGDAQEQKQVHPPGPSHVSELTQTEQTEE 654

Query: 690  EQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQT 749
            E   G           +  +L+ + QE  ++ DKLE++SAE + +L A++  E  S +Q 
Sbjct: 655  EDSSG------ETLSQLRERLELFTQERGEVLDKLEQLSAENL-QLQARL-EESSSSLQ- 705

Query: 750  QFGIDAKIQERDLYIE-NIESELSKYKSRICRLEESIAVME--DRRYSLERKADQLGSYL 806
               +  + +E+DL    +  S LS+  S + R  E +A ++  +    L  K ++  S L
Sbjct: 706  ---LLQREREKDLISSTSTSSNLSQELSSMQRSSEVVATLDAGEGGPVLFEKCEKSLSKL 762

Query: 807  QEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQ 866
              + +AY +   ++ +  N    L    +    QL E+ H+ KE     + +      + 
Sbjct: 763  NSELEAYRKANDRQAKF-NVSKKLAKEAKNCHTQLSELLHKVKEASTAVETVTVVETVVA 821

Query: 867  ISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIE 926
            ++  + +         A   +L ++  ++ + +L +L  +      E    IV    + E
Sbjct: 822  VTAPNGKALAEYEQLNAQNAEL-KAVISRLRQELDELRESYPET--EAPLAIVGSDSQRE 878

Query: 927  DLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNL 986
            D  ++  +Q+E A   +    ++ E+ ++ + +L     E    +   +  + +L ++  
Sbjct: 879  DEILQLQSQLEDARSLQAEQRQQIEEQVDQIKELRQTEAEQLQLVARQSAEITQL-QLQS 937

Query: 987  ELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDY 1046
            E  D+ +  ++       EQ      +L A  +  + E+  L   +   +   +  VS+ 
Sbjct: 938  EQFDQLLNSKEMSHEKQLEQQTRIRRELEARAESLEGELSILQTLVAEQKQQLIESVSES 997

Query: 1047 ESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQI---LVREQDDQIKELKETKLTFE 1103
            E  L     +L++ +EE++ + +   D  Q  E L++   LV +Q  ++   +ET     
Sbjct: 998  EHALNLKMLELQSAQEELREL-RAKEDPDQLREALRVSKSLVAQQVRELTSSQETVDALN 1056

Query: 1104 MNIPKTEGMIIS---------STIEPMSDDANNV-----DXXXXXXXXXXXXLKVQEEEE 1149
              I + +G+  +            E +   A N+     D             ++QE++E
Sbjct: 1057 QQIQEYQGLEHAHKEEQFKNRELREKLKKYALNLKKRTQDNADLEQKVQELTSQLQEQQE 1116

Query: 1150 FIQERSVLQEQSAKLNTELQECYTKIIQL-ETLNTELTGHDVVNQEQINQLKSKL---EQ 1205
             ++++  ++ +    N  +++   ++ +L E L  ++   ++ N++ + QLK ++   EQ
Sbjct: 1117 LVKQKEEVEREPIVDNHRVEQLQQQVSKLNEDLKAKI-HLNLENRDALRQLKQQIQEQEQ 1175

Query: 1206 LNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQRE--ADFQKTEHELRVQLSA 1263
            L  E D  L     +   +     +   E+ +L +++   RE  +  Q+  H L  +++ 
Sbjct: 1176 LIQERDAELQDANLVSKELRRERQEADQEVFQLGQENSRLREEISKLQEEIHNLGQRVNE 1235

Query: 1264 FESKYEQLLDSVQSSTQ--EETNKIVTMEQVT--SLQNKLQDKEEHLRNLQEKYADVINQ 1319
              +  E L   +++ ++  E++ +++ +   T  SLQ +LQ  ++   +  E   +    
Sbjct: 1236 EPTAVEDLRRQLEAKSKKFEKSKELIKLRNATIQSLQRELQQLQQDQDSEVEHVRNARAA 1295

Query: 1320 IEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKK 1379
             E LR E + E  A                 D      S++ ++ QS      E+ Q+ +
Sbjct: 1296 HEQLRLEKDAEITALRQEILKLERSRAAGEGDDTITKTSHQLLESQS--QQQAESLQVAE 1353

Query: 1380 SSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQ 1439
                           +     ++     Q  L   +       + +T+ +     E ++ 
Sbjct: 1354 -------------RELQQLRVQLTAAQEQHALLAQQYASDKANFEMTIARLETLHEGIQA 1400

Query: 1440 QLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESV 1499
            +L E    IE L   + +EL      + E A      Q  S+ ++V+++E+   ++ E  
Sbjct: 1401 KLQEDASYIESLE-AQNTELQARSAALEEQAASQANQQAASQ-DKVQILEQ---QLKEQR 1455

Query: 1500 SLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEIT--NLQNMVRASSSKIQKH 1557
               +Q  + ++ L+E   +  + + A +++++E++T   E +   L  +     S + KH
Sbjct: 1456 EQEEQKRQQDQQLQERFYELGQREQA-QSRQLELLTSEAEESRQQLAGLRTEYESLLAKH 1514

Query: 1558 VSFASDTKQGRDEQLDNTMNKELLDAVPRAELDLAMYMLH-QRDV 1601
             S  + T Q   EQ+ +   +EL +   R +LD+    LH QR V
Sbjct: 1515 -SQLTATAQAEREQMSSHSQEELAEL--RQQLDVKEADLHRQRQV 1556



 Score =  118 bits (284), Expect = 1e-24
 Identities = 196/984 (19%), Positives = 419/984 (42%), Gaps = 69/984 (7%)

Query: 148  SNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNK-----ATTXXXXXXXX 202
            +N  + K N    L  + K   T + +L  K+ E    +E         A T        
Sbjct: 772  ANDRQAKFNVSKKLAKEAKNCHTQLSELLHKVKEASTAVETVTVVETVVAVTAPNGKALA 831

Query: 203  XXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEA 262
                      + K  ++++++    +   +  E +  L  + S   R   + +    LE 
Sbjct: 832  EYEQLNAQNAELKAVISRLRQELDELRESYP-ETEAPLAIVGSDSQREDEILQLQSQLED 890

Query: 263  ARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMT 322
            AR   + +  ++ ++++Q              +A+QS E +   + +++ +   ++ N  
Sbjct: 891  ARSLQAEQRQQIEEQVDQIKELRQTEAEQLQLVARQSAEIT---QLQLQSEQFDQLLNSK 947

Query: 323  ELT--KKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTAS 380
            E++  K++E    +  ++    + LE +L+ + T   A        S   S  +      
Sbjct: 948  EMSHEKQLEQQTRIRRELEARAESLEGELSILQT-LVAEQKQQLIESVSESEHALNLKML 1006

Query: 381  KMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXX 440
            +++S   +L      +D D+      ++K  +V Q + +    +E V +           
Sbjct: 1007 ELQSAQEELRELRAKEDPDQLREALRVSK-SLVAQQVRELTSSQETVDALNQQIQEYQGL 1065

Query: 441  XXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQE-----QLKQELNDEIKD 495
                K+      +L  +      +L     +  D+ +  KVQE     Q +QEL  + ++
Sbjct: 1066 EHAHKEEQFKNRELREKLKKYALNLKKRTQDNADLEQ--KVQELTSQLQEQQELVKQKEE 1123

Query: 496  VNVKDLIE--KLKSAEEQITQLNDEIDAA-NKNMIKVKSNHKLK--LKQMQKTI-DNFSK 549
            V  + +++  +++  ++Q+++LN+++ A  + N+    +  +LK  +++ ++ I +  ++
Sbjct: 1124 VEREPIVDNHRVEQLQQQVSKLNEDLKAKIHLNLENRDALRQLKQQIQEQEQLIQERDAE 1183

Query: 550  VSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLA 609
            + D+N     L  E     Q+V +L +E   L+  +    S    E     + +  E  A
Sbjct: 1184 LQDANLVSKELRRERQEADQEVFQLGQENSRLREEI----SKLQEEIHNLGQRVNEEPTA 1239

Query: 610  ETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVH----LE 665
               L+     +S+KF+  +EL  ++ +   ++    ++ QLQ DQ  SE++ V       
Sbjct: 1240 VEDLRRQLEAKSKKFEKSKEL--IKLRNATIQSLQRELQQLQQDQD-SEVEHVRNARAAH 1296

Query: 666  EQIDALSASKKELALVIENLKLDKEQLYGTIKD---------LENDKEDIMNKLQNYIQE 716
            EQ+  L    +  AL  E LKL++ +  G   D         LE+  +     LQ   +E
Sbjct: 1297 EQL-RLEKDAEITALRQEILKLERSRAAGEGDDTITKTSHQLLESQSQQQAESLQVAERE 1355

Query: 717  NMDLTDKLEKMSAEKISELLA------KINHEEQ-SKIQTQF-GIDAKIQERDLYIENIE 768
               L  +++  +A++   LLA      K N E   ++++T   GI AK+QE   YIE++E
Sbjct: 1356 LQQL--RVQLTAAQEQHALLAQQYASDKANFEMTIARLETLHEGIQAKLQEDASYIESLE 1413

Query: 769  SELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLA 828
            ++ ++ ++R   LEE  A   +++ + + K   L   L+E+++   +   Q+ +L  R  
Sbjct: 1414 AQNTELQARSAALEEQAASQANQQAASQDKVQILEQQLKEQREQEEQKRQQDQQLQERFY 1473

Query: 829  VLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDL 888
             L   ++   +QL  +  E +E +++   L  E ++L    S +     A  E+   +  
Sbjct: 1474 ELGQREQAQSRQLELLTSEAEESRQQLAGLRTEYESLLAKHSQLTA--TAQAEREQMSSH 1531

Query: 889  AESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNE 948
            ++ E  + + QL   E++L R    +   +  K  E+++LE + N+ +E A  + + L +
Sbjct: 1532 SQEELAELRQQLDVKEADLHRQRQVYDAKLAAKATELDELECDLNSHVERAAAETRELCQ 1591

Query: 949  KYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYI 1008
            + E++ E V Q   +LQ        LN   +E+ +     + + V   + Q  D  EQ +
Sbjct: 1592 QLERSQELVAQRTEELQ-------RLNEEFQEVER-ERSTLSREVTLLRLQH-DSAEQDV 1642

Query: 1009 NEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVS 1068
             E+ +L     Q   E+  L  +I+    ++   +   + ++A+  T  +N  ++   + 
Sbjct: 1643 LELQELRMQAMQDKTEMDNLRTQIDALCANHSQELQALQQRIAELDTLGQNQTDDQVYIE 1702

Query: 1069 KQLLDSKQHNEELQI-LVREQDDQ 1091
             +     +   ELQ  L R+Q  Q
Sbjct: 1703 TENKRLAEQLSELQAQLARQQHQQ 1726



 Score = 95.5 bits (227), Expect = 1e-17
 Identities = 183/887 (20%), Positives = 384/887 (43%), Gaps = 101/887 (11%)

Query: 455  EHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQ 514
            E     E P  I VG++++  +EI ++Q QL     ++ + +      E+ +  EEQ+ Q
Sbjct: 859  ESYPETEAPLAI-VGSDSQREDEILQLQSQL-----EDARSLQA----EQRQQIEEQVDQ 908

Query: 515  LNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSN-----KEIVRLTEELHHLSQ 569
            +  E+       +++ +    ++ Q+Q   + F ++ +S      K++ + T     L  
Sbjct: 909  IK-ELRQTEAEQLQLVARQSAEITQLQLQSEQFDQLLNSKEMSHEKQLEQQTRIRRELEA 967

Query: 570  KVAELEEEKGNLQLHLVDYDSGRMIES------DVYKKMIEMENLAET--RLKAISLLES 621
            +   LE E   LQ  LV     ++IES       +  KM+E+++  E    L+A    + 
Sbjct: 968  RAESLEGELSILQT-LVAEQKQQLIESVSESEHALNLKMLELQSAQEELRELRAKEDPDQ 1026

Query: 622  QKFDLVQELHILQQKYDEVEDKLADISQL-QSDQVCSEIKSVHLEEQID--ALSASKKEL 678
             +  L     ++ Q+  E+      +  L Q  Q    ++  H EEQ     L    K+ 
Sbjct: 1027 LREALRVSKSLVAQQVRELTSSQETVDALNQQIQEYQGLEHAHKEEQFKNRELREKLKKY 1086

Query: 679  ALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAK 738
            AL ++    D   L   +++L +  ++    ++   +E ++    ++    E++ + ++K
Sbjct: 1087 ALNLKKRTQDNADLEQKVQELTSQLQEQQELVKQ--KEEVEREPIVDNHRVEQLQQQVSK 1144

Query: 739  INHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERK 798
            +N + ++KI     ++ +   R L  + I+ +    + R   L+++  V ++ R   +  
Sbjct: 1145 LNEDLKAKIH--LNLENRDALRQLK-QQIQEQEQLIQERDAELQDANLVSKELRRERQEA 1201

Query: 799  ADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQIL 858
              ++    QE  +   E +  ++E+ N    + +    VE    ++E ++K+ +K  +++
Sbjct: 1202 DQEVFQLGQENSRLREEISKLQEEIHNLGQRVNEEPTAVEDLRRQLEAKSKKFEKSKELI 1261

Query: 859  LEEN---QNLQISLSDMQQHYNALVEKANRTDLA--------ESESTKYQTQLRDLESNL 907
               N   Q+LQ  L  +QQ  ++ VE       A        ++E T  + ++  LE + 
Sbjct: 1262 KLRNATIQSLQRELQQLQQDQDSEVEHVRNARAAHEQLRLEKDAEITALRQEILKLERSR 1321

Query: 908  KR------ITH-EHQTLIVQKKKEIEDLEI------EFNTQIESAIRDKKVLNEKY---E 951
                    IT   HQ L  Q +++ E L++      +   Q+ +A     +L ++Y   +
Sbjct: 1322 AAGEGDDTITKTSHQLLESQSQQQAESLQVAERELQQLRVQLTAAQEQHALLAQQYASDK 1381

Query: 952  KNIEY-VTQLE-------AQLQEYKNNIENLNMNVEELNKMNLELIDKHVQK--QQTQSP 1001
             N E  + +LE       A+LQE  + IE+L     EL   +  L ++   +  QQ  S 
Sbjct: 1382 ANFEMTIARLETLHEGIQAKLQEDASYIESLEAQNTELQARSAALEEQAASQANQQAASQ 1441

Query: 1002 DYT---EQYINEINKLNALLKQKDEEI------IALNQKINNAQVSYM-SMVSDYESKLA 1051
            D     EQ + E  +     +Q+D+++      +   ++  + Q+  + S   +   +LA
Sbjct: 1442 DKVQILEQQLKEQREQEEQKRQQDQQLQERFYELGQREQAQSRQLELLTSEAEESRQQLA 1501

Query: 1052 QFTTKLENM-EEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTE 1110
               T+ E++  +  Q  +    + +Q +   Q  + E   Q+ ++KE  L  +  +   +
Sbjct: 1502 GLRTEYESLLAKHSQLTATAQAEREQMSSHSQEELAELRQQL-DVKEADLHRQRQVYDAK 1560

Query: 1111 GMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQE 1170
                ++ ++ +  D N+               +++  +E + +R+   E+  +LN E QE
Sbjct: 1561 LAAKATELDELECDLNS-HVERAAAETRELCQQLERSQELVAQRT---EELQRLNEEFQE 1616

Query: 1171 CYTKIIQLETLNTELT----GHDVVNQE--QINQLKSKLEQLNTENDNLLSTVAELRSSI 1224
                  +  TL+ E+T     HD   Q+  ++ +L+ +  Q  TE DNL + +  L ++ 
Sbjct: 1617 VER---ERSTLSREVTLLRLQHDSAEQDVLELQELRMQAMQDKTEMDNLRTQIDALCANH 1673

Query: 1225 SSAVDQRGFEIAELWKQHLAQREADFQ---KTEHE-LRVQLSAFESK 1267
            S  +      IAEL    L Q + D Q   +TE++ L  QLS  +++
Sbjct: 1674 SQELQALQQRIAEL--DTLGQNQTDDQVYIETENKRLAEQLSELQAQ 1718



 Score = 89.4 bits (212), Expect = 7e-16
 Identities = 162/919 (17%), Positives = 386/919 (42%), Gaps = 57/919 (6%)

Query: 318  IANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRN 377
            +A   +L  +   L+ +  ++RQ   EL             V S S++   ++  +S   
Sbjct: 830  LAEYEQLNAQNAELKAVISRLRQELDELRESYPETEAPLAIVGSDSQREDEILQLQSQLE 889

Query: 378  TASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXX 437
             A  +++   Q   E ++Q   K++ + E  +L++V +   +  + +  + SE+      
Sbjct: 890  DARSLQAEQRQQIEEQVDQI--KELRQTEAEQLQLVARQSAE--ITQLQLQSEQFDQLLN 945

Query: 438  XXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVN 497
                   K  L  Q ++  +      SL   G  +     +A+ ++QL + +++    +N
Sbjct: 946  SKEMSHEKQ-LEQQTRIRRELEARAESL--EGELSILQTLVAEQKQQLIESVSESEHALN 1002

Query: 498  VKDLIEKLKSAEEQITQLNDEIDAAN-KNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKE 556
            +K L  +L+SA+E++ +L  + D    +  ++V  +  L  +Q+++   +   V   N++
Sbjct: 1003 LKML--ELQSAQEELRELRAKEDPDQLREALRVSKS--LVAQQVRELTSSQETVDALNQQ 1058

Query: 557  IVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAI 616
            I       H   ++  +  E +  L+ + ++        +D+ +K+ E+ +  + + + +
Sbjct: 1059 IQEYQGLEHAHKEEQFKNRELREKLKKYALNLKKRTQDNADLEQKVQELTSQLQEQQELV 1118

Query: 617  SLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKK 676
               E  + + + + H ++Q   +V       S+L  D       ++   + +  L    +
Sbjct: 1119 KQKEEVEREPIVDNHRVEQLQQQV-------SKLNEDLKAKIHLNLENRDALRQLKQQIQ 1171

Query: 677  ELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELL 736
            E   +I+    + +      K+L  ++++   ++    QEN  L +++ K+  E+I  L 
Sbjct: 1172 EQEQLIQERDAELQDANLVSKELRRERQEADQEVFQLGQENSRLREEISKLQ-EEIHNLG 1230

Query: 737  AKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLE 796
             ++N E  +    +  ++AK ++ +   E I+   +  +S    L++   + +D+   +E
Sbjct: 1231 QRVNEEPTAVEDLRRQLEAKSKKFEKSKELIKLRNATIQSLQRELQQ---LQQDQDSEVE 1287

Query: 797  RKADQLGSYLQEKQKAYSEYTIQEDELVN--RLAVLMDHDRVVEKQLLEI-EHENKELQK 853
               +   ++ Q + +  +E T    E++   R     + D  + K   ++ E ++++  +
Sbjct: 1288 HVRNARAAHEQLRLEKDAEITALRQEILKLERSRAAGEGDDTITKTSHQLLESQSQQQAE 1347

Query: 854  KNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESEST--KYQTQLRDLESNLKRIT 911
              Q+   E Q L++ L+  Q+ + AL+ +   +D A  E T  + +T    +++ L+   
Sbjct: 1348 SLQVAERELQQLRVQLTAAQEQH-ALLAQQYASDKANFEMTIARLETLHEGIQAKLQEDA 1406

Query: 912  H-----EHQTLIVQKKKEIEDLEIEFNTQIESAIRDK-KVLNEKYEKNIEYVTQLEAQLQ 965
                  E Q   +Q +    + +       ++A +DK ++L ++ ++  E   Q   Q Q
Sbjct: 1407 SYIESLEAQNTELQARSAALEEQAASQANQQAASQDKVQILEQQLKEQREQEEQKRQQDQ 1466

Query: 966  EYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALL------- 1018
            + +     L    E+     LEL+    ++ + Q      +Y + + K + L        
Sbjct: 1467 QLQERFYELGQR-EQAQSRQLELLTSEAEESRQQLAGLRTEYESLLAKHSQLTATAQAER 1525

Query: 1019 ----KQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENME----EEMQRVSKQ 1070
                    EE+  L Q+++  +         Y++KLA   T+L+ +E      ++R + +
Sbjct: 1526 EQMSSHSQEELAELRQQLDVKEADLHRQRQVYDAKLAAKATELDELECDLNSHVERAAAE 1585

Query: 1071 LLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDX 1130
              +  Q  E  Q LV ++ ++++ L E    F+    +   +    T+  +  D+   D 
Sbjct: 1586 TRELCQQLERSQELVAQRTEELQRLNEE---FQEVERERSTLSREVTLLRLQHDSAEQDV 1642

Query: 1131 XXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDV 1190
                         +Q++ E    R+ +    A  + ELQ    +I +L+TL    T   V
Sbjct: 1643 LELQELRMQA---MQDKTEMDNLRTQIDALCANHSQELQALQQRIAELDTLGQNQTDDQV 1699

Query: 1191 VNQEQINQLKSKLEQLNTE 1209
              + +  +L  +L +L  +
Sbjct: 1700 YIETENKRLAEQLSELQAQ 1718



 Score = 84.2 bits (199), Expect = 3e-14
 Identities = 163/824 (19%), Positives = 339/824 (41%), Gaps = 84/824 (10%)

Query: 498  VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEI 557
            ++DL   +   E+    L  ++ A N+N+ + +   +L+L+Q    ++    +S+  +++
Sbjct: 1786 IEDLQRNVSDLEKHAQDLETKLLARNQNLAE-QEERRLQLEQRLSEVERL--LSERTQQL 1842

Query: 558  VRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIES---DVYKKMIEMENLAETRLK 614
              + +  +    ++A LE+         +D   G   E    D     +++  L +T   
Sbjct: 1843 ADI-QTANEERDRLAALEKLIQPAAAPTLDMFFGGQAEETVPDAVSHHLDL-GLPQTEPV 1900

Query: 615  AISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSAS 674
               L++ +K  L Q    +Q++  +  D   D     S    +E     +E     L   
Sbjct: 1901 VEPLIQPKKAYLCQPKQEIQEQTAQTIDWGVDEDPWAS--AANEAPQTDVEH----LHTR 1954

Query: 675  KKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISE 734
              +L L + N +  K +L      L    ++   K        + + + L+    E++  
Sbjct: 1955 IAQLELQLSNAEQQKTELQTKAAKLMKRLKEYKTKATTTATPTVTVDNDLDSTIIEELKH 2014

Query: 735  LLAKINHEEQSK---IQTQFGIDA-KIQERDLYIENIESELSKYKSRICRLEESIAVMED 790
             L ++     SK   I  Q  ++  K+ +R   +      +++ K R    +  + + + 
Sbjct: 2015 QL-QLQESRLSKAEEISQQHALEKEKLAKRIDVLTAGNDRMAEMKER---QDMDVQMYQA 2070

Query: 791  RRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKE 850
            R   L+ K  QL  + +      S  ++  DE   R+  L    + + +Q+ E+E E   
Sbjct: 2071 RIRELQEKLSQLDQWGEPAATVSS--SLDGDEAA-RIESLQQEIQQLRQQVSELEDERTR 2127

Query: 851  LQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRI 910
             Q +   L + +Q    +  + +     L ++ +     E+  T+ Q++L  L  + +  
Sbjct: 2128 DQAELGALRQSSQGYDEAEDNQKLELQQLRQQESEL---EALRTRDQSELEALRQSCQG- 2183

Query: 911  THEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNN 970
             H+    I   +++ + LE++   Q+  AI + + L  + +      T+LEA  Q  + +
Sbjct: 2184 -HDETVRIATLQQDNQQLELQ---QLRQAIIELETLRARDQ------TELEALRQSSQGH 2233

Query: 971  IENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQ 1030
             E   + +E+ +   LEL                +Q   ++ +L AL  +   E+ AL Q
Sbjct: 2234 DEAARIAIEQRDNQQLEL----------------QQLRQQLIELEALRARDQAELEALRQ 2277

Query: 1031 KINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDD 1090
                 Q+S + M S  + ++AQ   K   +    QR+ + + + +      +IL + Q+ 
Sbjct: 2278 SCQGQQLS-VDMASRNDEQMAQLQEKESEIVHLKQRIEELMREDQTEKLVFEILTKNQEL 2336

Query: 1091 QIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEF 1150
            Q+  ++  +L  +      E   +S+   P  DD   V+                EEE  
Sbjct: 2337 QLLRMQVKQLEEDK-----EDQQVSAA--PPKDDGETVEKLKSLCQQLQQEKSDMEEELR 2389

Query: 1151 IQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTEN 1210
            +    VL   S +L   +++    ++QL+T N E+T  ++    +I Q ++  +    E 
Sbjct: 2390 VLNNHVLS--SLELEDRMKQT---LLQLDTKNIEIT--ELRRSLEILQSQNLGQNSAAEQ 2442

Query: 1211 DNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQ 1270
               LS + +    +   V+Q+  E+A +W++HL+QREA F       + QL     + ++
Sbjct: 2443 IPDLSAINQQWEQL---VEQKCGEVASIWQEHLSQREAAF-------KAQLEEVTQQQQR 2492

Query: 1271 LLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYA 1314
             L   Q STQ E     T + +  +Q  L+ +E  +  L+E+ A
Sbjct: 2493 ELPQSQQSTQGE----ATSDIMQKMQKALETQEMEIVTLKEQLA 2532



 Score = 79.4 bits (187), Expect = 8e-13
 Identities = 265/1460 (18%), Positives = 578/1460 (39%), Gaps = 131/1460 (8%)

Query: 152  KEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIE-AKNKATTXXXXXXXXXXXXXXXX 210
            +E +     L+ ++ I++T + + ++++ E     E A N                    
Sbjct: 963  RELEARAESLEGELSILQTLVAEQKQQLIESVSESEHALNLKMLELQSAQEELRELRAKE 1022

Query: 211  XEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLE 270
              D  ++  ++ ++ +A +       Q  +  +  +      LE A+K  +    E+  +
Sbjct: 1023 DPDQLREALRVSKSLVAQQVRELTSSQETVDALNQQIQEYQGLEHAHKEEQFKNRELREK 1082

Query: 271  HSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPS--CEEKTEIEEKGSLEIANMTELTKKI 328
              K A  L++              L  Q  E     ++K E+E +  ++   + +L +++
Sbjct: 1083 LKKYALNLKKRTQDNADLEQKVQELTSQLQEQQELVKQKEEVEREPIVDNHRVEQLQQQV 1142

Query: 329  ELL-EHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWS 387
              L E L  +I   +  LEN+ A      + +    ++   LI  +      + + S   
Sbjct: 1143 SKLNEDLKAKI---HLNLENRDAL-----RQLKQQIQEQEQLIQERDAELQDANLVS--K 1192

Query: 388  QLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDT 447
            +L  E    D +      E ++L   I  L +++ +    ++E+ T            + 
Sbjct: 1193 ELRRERQEADQEVFQLGQENSRLREEISKLQEEIHNLGQRVNEEPTAV----------ED 1242

Query: 448  LIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDV-NVKDLIEKLK 506
            L  QL+ + ++  +   LI +   T  +  + +  +QL+Q+ + E++ V N +   E+L+
Sbjct: 1243 LRRQLEAKSKKFEKSKELIKLRNAT--IQSLQRELQQLQQDQDSEVEHVRNARAAHEQLR 1300

Query: 507  SAEE-QITQLNDEIDAANKNMIK-------VKSNHKLKLKQMQKTIDNFSKVSDSNKEI- 557
              ++ +IT L  EI    ++           K++H+L   Q Q+  ++        +++ 
Sbjct: 1301 LEKDAEITALRQEILKLERSRAAGEGDDTITKTSHQLLESQSQQQAESLQVAERELQQLR 1360

Query: 558  VRLTEELHHLSQKVAELEEEKGNLQLHLVDYDS------GRMIESDVYKKMIEMENLAET 611
            V+LT      +    +   +K N ++ +   ++       ++ E   Y + +E +N   T
Sbjct: 1361 VQLTAAQEQHALLAQQYASDKANFEMTIARLETLHEGIQAKLQEDASYIESLEAQN---T 1417

Query: 612  RLKAISL-LESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDA 670
             L+A S  LE Q      +    Q K   +E +L +  + Q +Q     +   L+E+   
Sbjct: 1418 ELQARSAALEEQAASQANQQAASQDKVQILEQQLKEQRE-QEEQ--KRQQDQQLQERFYE 1474

Query: 671  LSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAE 730
            L   ++  +  +E L  + E+    +  L  + E ++ K            +++   S E
Sbjct: 1475 LGQREQAQSRQLELLTSEAEESRQQLAGLRTEYESLLAKHSQLTATAQAEREQMSSHSQE 1534

Query: 731  KISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMED 790
            +++EL  +++ +E    + +   DAK+  +   ++ +E +L+ +      +E + A   +
Sbjct: 1535 ELAELRQQLDVKEADLHRQRQVYDAKLAAKATELDELECDLNSH------VERAAAETRE 1588

Query: 791  RRYSLERKADQLGSYLQEKQKAYSEYTIQEDE---LVNRLAVL-MDHDRVVEKQLLEIEH 846
                LER  + +    +E Q+   E+   E E   L   + +L + HD   E+ +LE++ 
Sbjct: 1589 LCQQLERSQELVAQRTEELQRLNEEFQEVERERSTLSREVTLLRLQHDSA-EQDVLELQE 1647

Query: 847  ENKE-LQKKNQILLEENQNLQISL--SDMQQHYNALVEKA--------NRTD---LAESE 892
               + +Q K ++   +N   QI    ++  Q   AL ++         N+TD     E+E
Sbjct: 1648 LRMQAMQDKTEM---DNLRTQIDALCANHSQELQALQQRIAELDTLGQNQTDDQVYIETE 1704

Query: 893  STKYQTQLRDLESNLKRITHE-----HQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLN 947
            + +   QL +L++ L R  H+     H    VQ ++      + F     +A      + 
Sbjct: 1705 NKRLAEQLSELQAQLARQQHQQQQQQHHHPAVQSQQHPPPASLFFGGDALAAPSPFDEIA 1764

Query: 948  EKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPD----- 1002
            +     +  +             IE+L  NV +L K   +L  K + + Q  +       
Sbjct: 1765 QPLR--VSSLAASAPPPISPPPTIEDLQRNVSDLEKHAQDLETKLLARNQNLAEQEERRL 1822

Query: 1003 YTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEE 1062
              EQ ++E+ +L +   Q+  +I   N++  +   +   ++    +         +  E 
Sbjct: 1823 QLEQRLSEVERLLSERTQQLADIQTANEE-RDRLAALEKLIQPAAAPTLDMFFGGQAEET 1881

Query: 1063 EMQRVSKQL-LDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPM 1121
                VS  L L   Q    ++ L++ +   + + K+     E      +  +        
Sbjct: 1882 VPDAVSHHLDLGLPQTEPVVEPLIQPKKAYLCQPKQE--IQEQTAQTIDWGVDEDPWASA 1939

Query: 1122 SDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLET- 1180
            +++A   D            L++   E   Q+++ LQ ++AKL   L+E  TK     T 
Sbjct: 1940 ANEAPQTDVEHLHTRIAQLELQLSNAE---QQKTELQTKAAKLMKRLKEYKTKATTTATP 1996

Query: 1181 ---LNTELTG---HDVVNQEQINQLK-SKLEQLNTENDNLLSTVAELRSSISSAVDQRGF 1233
               ++ +L      ++ +Q Q+ + + SK E+++ ++      +A+ R  + +A + R  
Sbjct: 1997 TVTVDNDLDSTIIEELKHQLQLQESRLSKAEEISQQHALEKEKLAK-RIDVLTAGNDRMA 2055

Query: 1234 EIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQ-V 1292
            E+ E     +   +A  +    EL+ +LS  +   E       S   +E  +I +++Q +
Sbjct: 2056 EMKERQDMDVQMYQARIR----ELQEKLSQLDQWGEPAATVSSSLDGDEAARIESLQQEI 2111

Query: 1293 TSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDL 1352
              L+ ++ + E+  R   +     + Q      E ED +                    L
Sbjct: 2112 QQLRQQVSELEDE-RTRDQAELGALRQSSQGYDEAEDNQ----KLELQQLRQQESELEAL 2166

Query: 1353 RTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELK 1412
            RT +QS  +   QS    ++E  ++  +             R    E + L    Q EL+
Sbjct: 2167 RTRDQSELEALRQSCQG-HDETVRIA-TLQQDNQQLELQQLRQAIIELETLRARDQTELE 2224

Query: 1413 DSEIYQKTHEYT--ITLTQRND---EFENVRQQLVEYEK-------RIEDLTYEKESELA 1460
                  + H+    I + QR++   E + +RQQL+E E         +E L    + +  
Sbjct: 2225 ALRQSSQGHDEAARIAIEQRDNQQLELQQLRQQLIELEALRARDQAELEALRQSCQGQQL 2284

Query: 1461 ILRLKMHENANHYETMQKESEIERVK-LIEELNVKITESVSLNKQVAELNKALEEEVAKT 1519
             + +    +    +  +KESEI  +K  IEEL ++  ++  L  ++   N+ L+    + 
Sbjct: 2285 SVDMASRNDEQMAQLQEKESEIVHLKQRIEEL-MREDQTEKLVFEILTKNQELQLLRMQV 2343

Query: 1520 NEMQTALENQEIEIVTLNDE 1539
             +++   E+Q++      D+
Sbjct: 2344 KQLEEDKEDQQVSAAPPKDD 2363



 Score = 79.4 bits (187), Expect = 8e-13
 Identities = 260/1440 (18%), Positives = 562/1440 (39%), Gaps = 135/1440 (9%)

Query: 213  DTKQQMTKMQENFIAMEAEWKDEKQRLLKDIES-KDVRISSLEEANKLLEAARFEISLEH 271
            + K +  +  +  I +        QR L+ ++  +D  +  +  A    E  R E   E 
Sbjct: 1248 EAKSKKFEKSKELIKLRNATIQSLQRELQQLQQDQDSEVEHVRNARAAHEQLRLEKDAEI 1307

Query: 272  SKLAQELE--QXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANM-TELTKKI 328
            + L QE+   +               + Q +E   +++ E  +    E+  +  +LT   
Sbjct: 1308 TALRQEILKLERSRAAGEGDDTITKTSHQLLESQSQQQAESLQVAERELQQLRVQLTAAQ 1367

Query: 329  ELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQ 388
            E    L  Q        E  +A + T  + + +  ++ +  I     +NT  + +S  + 
Sbjct: 1368 EQHALLAQQYASDKANFEMTIARLETLHEGIQAKLQEDASYIESLEAQNTELQARS--AA 1425

Query: 389  LSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTL 448
            L  +  +Q   +  +++++  LE   Q L +    +E    +              +   
Sbjct: 1426 LEEQAASQANQQAASQDKVQILE---QQLKEQREQEEQKRQQDQQLQERFYELGQREQAQ 1482

Query: 449  IAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSA 508
              QL+L   +  E    +  G  TE  + +AK   QL      E + ++          +
Sbjct: 1483 SRQLELLTSEAEESRQQL-AGLRTEYESLLAK-HSQLTATAQAEREQMS--------SHS 1532

Query: 509  EEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLS 568
            +E++ +L  ++D    ++ + +  +  KL      +D      D N  + R   E   L 
Sbjct: 1533 QEELAELRQQLDVKEADLHRQRQVYDAKLAAKATELDELE--CDLNSHVERAAAETRELC 1590

Query: 569  QKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQ 628
            Q++   +E                     V ++  E++ L E        +E ++  L +
Sbjct: 1591 QQLERSQEL--------------------VAQRTEELQRLNEE----FQEVERERSTLSR 1626

Query: 629  ELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLD 688
            E+ +L+ ++D  E  + ++ +L+   +  + +  +L  QIDAL A+  +    ++    +
Sbjct: 1627 EVTLLRLQHDSAEQDVLELQELRMQAMQDKTEMDNLRTQIDALCANHSQELQALQQRIAE 1686

Query: 689  KEQLYGTIKDLENDKEDIMNKLQNYIQ-ENMDLTDKLEKMSAEKISELLAKINHEEQSK- 746
             + L       +N  +D     Q YI+ EN  L ++L ++ A+     LA+  H++Q + 
Sbjct: 1687 LDTLG------QNQTDD-----QVYIETENKRLAEQLSELQAQ-----LARQQHQQQQQQ 1730

Query: 747  -----IQTQ---------FGIDAKIQER--DLYIENIE-SELSKYKSRICRLEESIAVME 789
                 +Q+Q         FG DA       D   + +  S L+           +I  ++
Sbjct: 1731 HHHPAVQSQQHPPPASLFFGGDALAAPSPFDEIAQPLRVSSLAASAPPPISPPPTIEDLQ 1790

Query: 790  DRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENK 849
                 LE+ A  L + L  + +  +E   +  +L  RL+ +        +QL +I+  N+
Sbjct: 1791 RNVSDLEKHAQDLETKLLARNQNLAEQEERRLQLEQRLSEVERLLSERTQQLADIQTANE 1850

Query: 850  ELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKR 909
            E   ++++   E      +   +   +    E+     + ++ S      L   E  ++ 
Sbjct: 1851 E---RDRLAALEKLIQPAAAPTLDMFFGGQAEET----VPDAVSHHLDLGLPQTEPVVEP 1903

Query: 910  ITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKN 969
            +    +  + Q K+EI++   +               NE  + ++E++    AQL+   +
Sbjct: 1904 LIQPKKAYLCQPKQEIQEQTAQTIDWGVDEDPWASAANEAPQTDVEHLHTRIAQLELQLS 1963

Query: 970  NIENLNMNVE-ELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIAL 1028
            N E     ++ +  K+   L +   +   T +P  T    N+++  + ++++   ++   
Sbjct: 1964 NAEQQKTELQTKAAKLMKRLKEYKTKATTTATPTVTVD--NDLD--STIIEELKHQLQLQ 2019

Query: 1029 NQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVS-KQLLDSKQHNEELQILVRE 1087
              +++ A+        + E KLA+    L    + M  +  +Q +D + +   ++ L +E
Sbjct: 2020 ESRLSKAEEISQQHALEKE-KLAKRIDVLTAGNDRMAEMKERQDMDVQMYQARIREL-QE 2077

Query: 1088 QDDQIKELKETKLTFEMNIPKTEGMIISST---IEPMSDDANNVDXXXXXXXXXXXXLKV 1144
            +  Q+ +  E   T   ++   E   I S    I+ +    + ++            L+ 
Sbjct: 2078 KLSQLDQWGEPAATVSSSLDGDEAARIESLQQEIQQLRQQVSELEDERTRDQAELGALRQ 2137

Query: 1145 QEE--EEFIQERSVLQEQSAKLNTELQECYTKI-IQLETLNTELTGHD----VVNQEQIN 1197
              +  +E    + +  +Q  +  +EL+   T+   +LE L     GHD    +   +Q N
Sbjct: 2138 SSQGYDEAEDNQKLELQQLRQQESELEALRTRDQSELEALRQSCQGHDETVRIATLQQDN 2197

Query: 1198 QLKSKLEQLNTENDNLLSTVAELRSSISSA--VDQRGFEIAELWKQHLAQREADFQKTEH 1255
            Q + +L+QL      L +  A  ++ + +     Q   E A +  +    ++ + Q+   
Sbjct: 2198 Q-QLELQQLRQAIIELETLRARDQTELEALRQSSQGHDEAARIAIEQRDNQQLELQQLRQ 2256

Query: 1256 ELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYAD 1315
            +L ++L A  ++ +  L++++ S Q +   +    +      +LQ+KE  + +L+++   
Sbjct: 2257 QL-IELEALRARDQAELEALRQSCQGQQLSVDMASRNDEQMAQLQEKESEIVHLKQR--- 2312

Query: 1316 VINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENA 1375
                IE L  E + EK+ F                    E++  +Q+      +  E   
Sbjct: 2313 ----IEELMREDQTEKLVFEILTKNQELQLLRMQVKQLEEDKEDQQVSAAPPKDDGETVE 2368

Query: 1376 QLKKSSXXXXXXXXXXXXRVNDAEAKVLE-LTHQLELKDSEIYQKTHEYTITLTQRNDEF 1434
            +LK                +      VL  L  +  +K + +   T    IT  +R+ E 
Sbjct: 2369 KLKSLCQQLQQEKSDMEEELRVLNNHVLSSLELEDRMKQTLLQLDTKNIEITELRRSLEI 2428

Query: 1435 ---ENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEEL 1491
               +N+ Q      ++I DL+   +    ++  K  E A+ ++    + E      +EE+
Sbjct: 2429 LQSQNLGQNSAA--EQIPDLSAINQQWEQLVEQKCGEVASIWQEHLSQREAAFKAQLEEV 2486

Query: 1492 NVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEIT-NLQNMVRAS 1550
              +    +  ++Q  +  +A  + + K   MQ ALE QE+EIVTL +++        R +
Sbjct: 2487 TQQQQRELPQSQQSTQ-GEATSDIMQK---MQKALETQEMEIVTLKEQLAIRSAEYARLA 2542

Query: 1551 SS----KIQKHVSFA----SDTKQGRDEQLDNTMNKELLDAVPRAELDLAMYMLHQRDVR 1602
            +     ++Q     +    + T          T N+ L + V +A+LD A+ MLHQRD+R
Sbjct: 2543 AQYDPFRLQNRGGASGGNPASTTVSAGGPPSLTANEPLPEYVLKADLDYALMMLHQRDMR 2602


>UniRef50_A0CKT9 Cluster: Chromosome undetermined scaffold_20, whole
            genome shotgun sequence; n=2; Paramecium tetraurelia|Rep:
            Chromosome undetermined scaffold_20, whole genome shotgun
            sequence - Paramecium tetraurelia
          Length = 932

 Score =  135 bits (326), Expect = 1e-29
 Identities = 200/940 (21%), Positives = 411/940 (43%), Gaps = 100/940 (10%)

Query: 628  QELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDAL-SASKKELALVIENLK 686
            +EL I + KY+ ++ +   ++QL+  Q     + ++  + ++ +   S  +   ++ N  
Sbjct: 38   KELEIWKDKYETLQKRWDTLNQLKEKQDGKTKQDINDSKTLNQVPKTSGHQQTSLLPNT- 96

Query: 687  LDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSK 746
             +K+Q    ++ L       + K +  IQE   L+D+ EK S   I     +I +++ S+
Sbjct: 97   -EKQQFQILVQQLNEQ----IAKQKKQIQE---LSDRNEKHS---IDNKKLEIENKKYSE 145

Query: 747  IQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYL 806
               QF   +  +  D        ++ +Y+  + +  ++I  M+  + S E++ ++L    
Sbjct: 146  QLNQFRKTSHHKFND-------QQMLQYEENVQKFIQTIDEMKQEKNSFEKQIEKLTKEN 198

Query: 807  QEKQKAYSEY--TIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQN 864
            Q  Q++  E   +IQE +   +      H    + Q+ E+  +N +L+K  + L +++Q+
Sbjct: 199  QSLQQSNDELKKSIQEHDKGQQ------HKNQFQLQISELGLKNNQLEKLVKDLEKQSQH 252

Query: 865  LQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKE 924
             Q  LS  +Q    + +K       +++  +YQ +L +L + L+ + +E Q  + Q  + 
Sbjct: 253  QQ-DLS--KQTAKQMDDKQQEIQSLQNKVQEYQKELSNL-NQLQDVYNEQQLQLQQLAQV 308

Query: 925  IEDLE--IEFNTQIESAIRDKKVLNEKYEKNIEYVTQLE--------------AQLQEYK 968
            I++LE  +  +T  +S   + K ++ KY+   +  T L+              +QL++ K
Sbjct: 309  IQELEGKLSESTNPQSYESEIKQISIKYDDLYQQYTDLQTQDIMKQEWLNLQKSQLEDLK 368

Query: 969  NNIENLNMNVEELNKMNLELIDK-HVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIA 1027
               + L+  +EEL K N  LI +  +QK +T+    + Q  ++IN    ++  K+EEI  
Sbjct: 369  QENDQLSQKIEELQKQNDVLIGQIEIQKDETKLS--SSQLQDQINSYEHIVSDKNEEIHK 426

Query: 1028 LNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQ-HNEELQILVR 1086
            L  ++   + S  +   DYE K+ Q  T+ E +E E    SK  ++  +  N EL+  + 
Sbjct: 427  LKVELTKQKCSLKN--DDYEEKIQQLKTQYEKLESE----SKMKIEWMEIQNTELEETIN 480

Query: 1087 EQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKV-- 1144
            E + +I+   E       N P+ +   I+   E +      V+            +K   
Sbjct: 481  EYEKKIQNFVEQLNQINKNNPEDQSQKITELKEHLQQYELIVNNKNFEIDELKKQIKEIN 540

Query: 1145 --QEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSK 1202
              Q +E+F ++   L+ Q  KL TE Q       Q + +  E        QEQIN L ++
Sbjct: 541  QKQNDEDFEKKYLNLKTQFEKLETENQMKQ----QWQNIQEE------EQQEQINTLNAQ 590

Query: 1203 LEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQK--TEHELRVQ 1260
            + +LN + ++  +   +L++ +   VD+   ++++  +QHL   +  F      + LR  
Sbjct: 591  IVELNDQLNSTQNLYLKLQTDLQQEVDKNE-QLSKQSQQHLLDIQNSFNSGNIRNALRKS 649

Query: 1261 LSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQI 1320
            +   ES +E   +  +++ ++  N +   E++ +L  +L + EE+  NLQ++  ++  Q 
Sbjct: 650  IKKEES-FEDEANIKKNADEKCINDL--KEKIQTLNEELGEYEENQSNLQQQIGELTEQK 706

Query: 1321 EILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLR----------TENQSYKQMQEQSILNI 1370
              ++ + E E   +                DL            ENQ   Q  E  +L +
Sbjct: 707  NKIQLQYE-EMYNYYSKAYDQIQNFITQVEDLNKIILDKENQIVENQYQIQQLEDQLLQM 765

Query: 1371 NEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLE-LKDSEIYQKTHEYTITLTQ 1429
            NE N      +            R  + E  +  L  QLE   D E YQK ++    +  
Sbjct: 766  NEINKDAYTENQDINQMKAFYEQRFLEQETLIQNLQQQLEQTSDQEYYQKMNQ----ILH 821

Query: 1430 RNDEFENVR----QQLVEYEKRIEDLTYEKESELAIL-RLKMHENANHYETMQKESEIER 1484
             N+E + +R    ++L + ++ IE+L  +  S+  +     + E     E + K  + ++
Sbjct: 822  ENEELKQLRSENQEELNKKDQLIEELQMQMLSQSQVTGSSDLQERKRRQELLDKVKD-DK 880

Query: 1485 VKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQT 1524
             +  E  N ++ + +      A    +L+ +  +    QT
Sbjct: 881  SEKSESSNEQLVKKIGKKTSGASAKLSLKLDYNQDGSKQT 920



 Score =  111 bits (268), Expect = 1e-22
 Identities = 197/882 (22%), Positives = 394/882 (44%), Gaps = 96/882 (10%)

Query: 484  QLKQELNDEIKDVNV-KDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQK 542
            + K E     K++ + KD  E L+   + + QL ++ D   K  I    N    L Q+ K
Sbjct: 28   RFKFEKEASSKELEIWKDKYETLQKRWDTLNQLKEKQDGKTKQDI----NDSKTLNQVPK 83

Query: 543  TIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKM 602
            T  +       N E  +    +  L++++A+   +K  +Q  L D +    I++    K 
Sbjct: 84   TSGHQQTSLLPNTEKQQFQILVQQLNEQIAK---QKKQIQ-ELSDRNEKHSIDN----KK 135

Query: 603  IEMENLAET-RLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKS 661
            +E+EN   + +L         KF+  Q L    Q  + V+  +  I +++ ++   E + 
Sbjct: 136  LEIENKKYSEQLNQFRKTSHHKFNDQQML----QYEENVQKFIQTIDEMKQEKNSFEKQI 191

Query: 662  VHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLT 721
              L ++  +L  S  EL   I+  + DK Q +     L+  +  + N   N +++   L 
Sbjct: 192  EKLTKENQSLQQSNDELKKSIQ--EHDKGQQHKNQFQLQISELGLKN---NQLEK---LV 243

Query: 722  DKLEKMSAEK--ISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRIC 779
              LEK S  +  +S+  AK   ++Q +IQ+   +  K+QE    + N+      Y  +  
Sbjct: 244  KDLEKQSQHQQDLSKQTAKQMDDKQQEIQS---LQNKVQEYQKELSNLNQLQDVYNEQQL 300

Query: 780  RLEESIAVMEDRRYSLERKADQLGSYLQEKQKA--YSEYTIQEDELVNRLAVLMDHDRVV 837
            +L++   V+++    L    +      + KQ +  Y +   Q  +L  +  +  +   + 
Sbjct: 301  QLQQLAQVIQELEGKLSESTNPQSYESEIKQISIKYDDLYQQYTDLQTQDIMKQEWLNLQ 360

Query: 838  EKQLLEIEHEN-------KELQKKNQILLEE----NQNLQISLSDMQQHYNA----LVEK 882
            + QL +++ EN       +ELQK+N +L+ +        ++S S +Q   N+    + +K
Sbjct: 361  KSQLEDLKQENDQLSQKIEELQKQNDVLIGQIEIQKDETKLSSSQLQDQINSYEHIVSDK 420

Query: 883  ANRTDLAESESTKYQTQLR--DLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAI 940
                   + E TK +  L+  D E  ++++  +++ L  + K +IE +EI+ NT++E  I
Sbjct: 421  NEEIHKLKVELTKQKCSLKNDDYEEKIQQLKTQYEKLESESKMKIEWMEIQ-NTELEETI 479

Query: 941  RD--KKV------LNEKYEKNIE----YVTQLEAQLQEYKNNIENLNMNVEELNKMNLEL 988
             +  KK+      LN+  + N E     +T+L+  LQ+Y+  + N N  ++EL K   E+
Sbjct: 480  NEYEKKIQNFVEQLNQINKNNPEDQSQKITELKEHLQQYELIVNNKNFEIDELKKQIKEI 539

Query: 989  IDKHVQKQQTQSPDYTEQYIN---EINKLNA--LLKQKDEEIIALNQ--KIN--NAQVSY 1039
                   Q+    D+ ++Y+N   +  KL     +KQ+ + I    Q  +IN  NAQ+  
Sbjct: 540  ------NQKQNDEDFEKKYLNLKTQFEKLETENQMKQQWQNIQEEEQQEQINTLNAQIVE 593

Query: 1040 MS-MVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQD--DQIKE-- 1094
            ++  ++  ++   +  T L+   ++ +++SKQ   S+QH  ++Q      +  + +++  
Sbjct: 594  LNDQLNSTQNLYLKLQTDLQQEVDKNEQLSKQ---SQQHLLDIQNSFNSGNIRNALRKSI 650

Query: 1095 LKETKLTFEMNIPKT--EGMI--ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEF 1150
             KE     E NI K   E  I  +   I+ ++++    +            L  Q+ +  
Sbjct: 651  KKEESFEDEANIKKNADEKCINDLKEKIQTLNEELGEYEENQSNLQQQIGELTEQKNKIQ 710

Query: 1151 IQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTEN 1210
            +Q   +    S K   ++Q   T++  L  +  +     V NQ QI QL+ +L Q+N  N
Sbjct: 711  LQYEEMYNYYS-KAYDQIQNFITQVEDLNKIILDKENQIVENQYQIQQLEDQLLQMNEIN 769

Query: 1211 DNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQ 1270
             +  +   ++ + + +  +QR  E  E   Q+L Q+    Q ++ E   +++    + E+
Sbjct: 770  KDAYTENQDI-NQMKAFYEQRFLE-QETLIQNLQQQLE--QTSDQEYYQKMNQILHENEE 825

Query: 1271 LLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEK 1312
             L  ++S  QEE NK   + +   +Q   Q +     +LQE+
Sbjct: 826  -LKQLRSENQEELNKKDQLIEELQMQMLSQSQVTGSSDLQER 866



 Score = 87.0 bits (206), Expect = 4e-15
 Identities = 169/798 (21%), Positives = 327/798 (40%), Gaps = 112/798 (14%)

Query: 829  VLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDL 888
            VL  + ++ E+  L  + E +   K+ +I  ++ + LQ     + Q    L EK +    
Sbjct: 14   VLKQYKKMYEEICLRFKFEKEASSKELEIWKDKYETLQKRWDTLNQ----LKEKQDGKTK 69

Query: 889  AESESTKYQTQLRDLESNLKRITHEHQTLIVQ-KKKEIEDLEIEFNTQIESAIRDKKVLN 947
             +   +K   Q+       K   H+  +L+   +K++ + L  + N QI    + KK + 
Sbjct: 70   QDINDSKTLNQVP------KTSGHQQTSLLPNTEKQQFQILVQQLNEQIA---KQKKQIQ 120

Query: 948  EKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQY 1007
            E  ++N ++       +   K  IEN   + E+LN+       K   +Q  Q  +  +++
Sbjct: 121  ELSDRNEKH------SIDNKKLEIENKKYS-EQLNQFRKTSHHKFNDQQMLQYEENVQKF 173

Query: 1008 INEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRV 1067
            I  I+++       +++I  L ++  + Q S     +D   K  Q   K +  + + Q  
Sbjct: 174  IQTIDEMKQEKNSFEKQIEKLTKENQSLQQS-----NDELKKSIQEHDKGQQHKNQFQL- 227

Query: 1068 SKQLLDSKQHNEELQILVREQDDQIKELKE-TKLTF-EMNIPKTEGMIISSTIEPMSDDA 1125
              Q+ +    N +L+ LV++ + Q +  ++ +K T  +M+  + E   + + ++    + 
Sbjct: 228  --QISELGLKNNQLEKLVKDLEKQSQHQQDLSKQTAKQMDDKQQEIQSLQNKVQEYQKEL 285

Query: 1126 NNVDXXXXXXXXXXXXLKVQEEEEFIQE-RSVLQEQS--AKLNTELQECYTKIIQLETLN 1182
            +N++            L++Q+  + IQE    L E +      +E+++   K   L    
Sbjct: 286  SNLNQLQDVYNEQQ--LQLQQLAQVIQELEGKLSESTNPQSYESEIKQISIKYDDLYQQY 343

Query: 1183 TELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSS-------ISSAVDQRGFEI 1235
            T+L   D++ QE +N  KS+LE L  END L   + EL+         I    D+     
Sbjct: 344  TDLQTQDIMKQEWLNLQKSQLEDLKQENDQLSQKIEELQKQNDVLIGQIEIQKDETKLSS 403

Query: 1236 AELWKQHLAQREADFQKTE--HELRVQLSA---------FESKYEQLLDSVQSSTQEETN 1284
            ++L  Q  +       K E  H+L+V+L+          +E K +QL    +    E   
Sbjct: 404  SQLQDQINSYEHIVSDKNEEIHKLKVELTKQKCSLKNDDYEEKIQQLKTQYEKLESESKM 463

Query: 1285 KIVTME-QVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXX 1343
            KI  ME Q T L+  + + E+ ++N  E+    +NQI     E + +K+           
Sbjct: 464  KIEWMEIQNTELEETINEYEKKIQNFVEQ----LNQINKNNPEDQSQKIT---------- 509

Query: 1344 XXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVL 1403
                   +L+   Q Y+ +       I+E   Q+K+ +               D E K L
Sbjct: 510  -------ELKEHLQQYELIVNNKNFEIDELKKQIKEINQKQND---------EDFEKKYL 553

Query: 1404 ELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVE-----------YEKRIEDLT 1452
             L  Q E  ++E   K     I   ++ ++   +  Q+VE           Y K   DL 
Sbjct: 554  NLKTQFEKLETENQMKQQWQNIQEEEQQEQINTLNAQIVELNDQLNSTQNLYLKLQTDLQ 613

Query: 1453 YE--------KESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQ 1504
             E        K+S+  +L ++   N+ +     ++S  +     +E N+K          
Sbjct: 614  QEVDKNEQLSKQSQQHLLDIQNSFNSGNIRNALRKSIKKEESFEDEANIKKNADEKCIND 673

Query: 1505 VAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDT 1564
            + E  + L EE+ +  E Q+ L+ Q         E+T  +N ++    ++  + S A D 
Sbjct: 674  LKEKIQTLNEELGEYEENQSNLQQQ-------IGELTEQKNKIQLQYEEMYNYYSKAYDQ 726

Query: 1565 KQGRDEQLDNTMNKELLD 1582
             Q    Q+++ +NK +LD
Sbjct: 727  IQNFITQVED-LNKIILD 743



 Score = 60.1 bits (139), Expect = 5e-07
 Identities = 86/442 (19%), Positives = 190/442 (42%), Gaps = 34/442 (7%)

Query: 1189 DVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSA-VDQRGFEIAELWKQHLAQRE 1247
            D + QE+ N  + ++E+L  EN +L  +  EL+ SI      Q+     +L    L  + 
Sbjct: 178  DEMKQEK-NSFEKQIEKLTKENQSLQQSNDELKKSIQEHDKGQQHKNQFQLQISELGLKN 236

Query: 1248 ADFQKTEHELRVQLSAFESKYEQL---LDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEE 1304
               +K   +L  Q    +   +Q    +D  Q   Q   NK+   ++  S  N+LQD   
Sbjct: 237  NQLEKLVKDLEKQSQHQQDLSKQTAKQMDDKQQEIQSLQNKVQEYQKELSNLNQLQDVYN 296

Query: 1305 HLRNLQEKYADVINQIEILRSEIEDEKV--AFXXXXXXXXXXXXXXXXDLRTEN---QSY 1359
              +   ++ A VI ++E   SE  + +   +                 DL+T++   Q +
Sbjct: 297  EQQLQLQQLAQVIQELEGKLSESTNPQSYESEIKQISIKYDDLYQQYTDLQTQDIMKQEW 356

Query: 1360 KQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRV----NDAEAKVLELTHQLELKD-- 1413
              +Q+  + ++ +EN QL +              ++    ++ +    +L  Q+   +  
Sbjct: 357  LNLQKSQLEDLKQENDQLSQKIEELQKQNDVLIGQIEIQKDETKLSSSQLQDQINSYEHI 416

Query: 1414 -SEIYQKTHEYTITLTQ-----RNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMH 1467
             S+  ++ H+  + LT+     +ND++E   QQL    +++E  +  K   + I   ++ 
Sbjct: 417  VSDKNEEIHKLKVELTKQKCSLKNDDYEEKIQQLKTQYEKLESESKMKIEWMEIQNTELE 476

Query: 1468 ENANHYETMQKESEIERVKLI-----EELNVKITESVSLNKQVAELNKALEEEVAKTNEM 1522
            E  N YE  + ++ +E++  I     E+ + KITE   L + + +    +  +  + +E+
Sbjct: 477  ETINEYE-KKIQNFVEQLNQINKNNPEDQSQKITE---LKEHLQQYELIVNNKNFEIDEL 532

Query: 1523 QTALE--NQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKEL 1580
            +  ++  NQ+        +  NL+       ++ Q    + +  ++ + EQ+ NT+N ++
Sbjct: 533  KKQIKEINQKQNDEDFEKKYLNLKTQFEKLETENQMKQQWQNIQEEEQQEQI-NTLNAQI 591

Query: 1581 LDAVPRAELDLAMYMLHQRDVR 1602
            ++   +      +Y+  Q D++
Sbjct: 592  VELNDQLNSTQNLYLKLQTDLQ 613


>UniRef50_A0CCF8 Cluster: Chromosome undetermined scaffold_167, whole
            genome shotgun sequence; n=4; Paramecium tetraurelia|Rep:
            Chromosome undetermined scaffold_167, whole genome
            shotgun sequence - Paramecium tetraurelia
          Length = 2085

 Score =  135 bits (326), Expect = 1e-29
 Identities = 290/1540 (18%), Positives = 663/1540 (43%), Gaps = 126/1540 (8%)

Query: 140  QLGDVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXX 199
            Q  ++  + NT  + +  L  L+ ++ ++   ++ +++  N++ +I   K +  T     
Sbjct: 142  QKQELEQIINTYGDDEKILKQLKQQISVLNEQLV-VEKAYNQEVRIQLKKLQQETQNLND 200

Query: 200  XXXXXXXXXXXXED----TKQQMT--KMQENFIAMEAEWKDEKQRLLKDIESKDVRISSL 253
                        ED    TK Q+   K Q   + +    K E ++L+  I+    +  ++
Sbjct: 201  QLEMKLAEKQDFEDQVAKTKSQLDYLKSQNIMLGIGTPVKGETEKLIA-IDDLVKQNQAV 259

Query: 254  EEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIE-E 312
            ++    L+    E    H++L  +L +              L  QS+ P  E  +++E E
Sbjct: 260  DDLMNELQTKLLEKQQAHNQLMDQLSKQNIQENEQNSSTS-LRPQSLSPKKELISQLEVE 318

Query: 313  KGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISR 372
            +   EI       K++E+ E L  Q+ +  +E+      +  E +   S  ++   + SR
Sbjct: 319  QHECEIIQQQLKQKQLEI-EELRDQLEKEEQEVFRLQYKLQEEIEVKVSVEQQIQSVQSR 377

Query: 373  K---SGRNTASKMKSPWSQL---SSETLNQDTDKKIN--KNEIAKLEMVIQSLNKDLVDK 424
            +       T+   ++P   +    +E++ QD   +I+  K  I + E  I+ L  ++  K
Sbjct: 378  QLIIEPTVTSYIQEAPTINVFGPQTESIPQDYQFQIDQLKETIKQQESQIEFLKFEIQQK 437

Query: 425  EYVIS-EKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAK--V 481
            + +++  + T            ++ I +L+ +    ++    +    N ED     K  V
Sbjct: 438  DEIMNMSQHTYLQDLNQQNQEVESRIQELKKQLSYKIKRKDQLESIVN-EDQKPRRKSFV 496

Query: 482  QEQLKQELNDEI--KDVNVKDLIEKLKSAEEQITQLNDEI---DAANKNMIKVKSNHKLK 536
            Q     +L +++  K++N+  L E++   ++Q+     E+   D   +    +K+N    
Sbjct: 497  QNTELMDLQEQLHEKNMNIVQLYEEISRFQKQLYDKEQELQQRDVELRYQALMKTNEDQC 556

Query: 537  LKQMQKTIDNFSKVSDSNKEIVRLTE------ELHHL-SQKVAELEEEKGNLQLHL---- 585
             K  +    N S     +   VRL E      EL +L S K  E+E  + N   +     
Sbjct: 557  EKADELVKKNLSMDELIHSLEVRLVEKESKLKELEYLNSSKNFEIESNQNNNSFYKDRES 616

Query: 586  VDYDSG-RMIESDVYKKMIEMENLA---ETRLKAI-SLLESQKFDLVQELHILQQKYDEV 640
            +  DSG    + D   + ++ + +     + L+ + S +E QK++L ++  I++Q   ++
Sbjct: 617  IIRDSGINSYDQDQDHQFVQQQQILAGFNSGLEHLKSRVECQKYELQEKDKIIEQLKQQL 676

Query: 641  ED-KLADISQ--LQSDQVCSEIKSVH-LEEQIDALSASKKELALVIENL-------KLDK 689
             D K ++ +Q  L +  V    + ++ L+EQ D L      L  VI  L       K  +
Sbjct: 677  NDLKRSNFNQQILATQDVSVINRQINVLQEQADNLVKQNLALEDVIHELEYKLQEKKNKQ 736

Query: 690  EQLYGTIKDLENDKEDIMN-KLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQ 748
            E++   I+++  ++  +   K    +++N++L +K+++M +  I +   +   E++   Q
Sbjct: 737  EEVQQIIQNMMEEEVQLRQLKSDEMVKKNLELDEKIQQMESRLIQKQQQQYELEQRLS-Q 795

Query: 749  TQFGIDAKI----QERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGS 804
             Q  +  ++    +++D+ I++  S LS+   +I ++ ES+  +      LE    Q   
Sbjct: 796  HQRSMPQRLPVFHEDQDI-IQDHNSNLSELTIQIAQITESVRQLSQDDIELEFLLKQK-- 852

Query: 805  YLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQN 864
              +EKQ    +  +      + L  L    ++ ++Q+ +++ +NK++++    L  +  N
Sbjct: 853  --KEKQSQIEQLKLFIQSSTDVLQDLQSEQQIKQEQVEKMKSQNKDIEQMVNDLQNQQVN 910

Query: 865  LQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKE 924
            L   ++  QQ+    + +   +    +E  K Q ++++   NL+ +  + Q ++ +K++E
Sbjct: 911  LIEDVNKSQQNVPNWLNQNMESSKRLNELQKGQQKVKEQIKNLESLILDLQIVVKEKQEE 970

Query: 925  IEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIE-NLNMNVEELNK 983
            ++ +  E N Q+        +L  K ++  +++ + +  L E    +E  +N  V E  +
Sbjct: 971  LQRISQE-NYQL-------SILTRKQKQKRDHLLREQMPLGEKVGLLEQQVNDLVAENKR 1022

Query: 984  MNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMV 1043
            + LEL     + +  +    T++   +I+ L+    Q D+ I+ L   I  A++    ++
Sbjct: 1023 LQLELARLFQEAESAKQVKQTKE--QQISALSIESSQLDQNIMLLKDDIEQAKILEQQLL 1080

Query: 1044 SDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFE 1103
                    Q+  K   +E+E++  ++  LD    N++++ L  +  ++ K+L E +L  E
Sbjct: 1081 DQQN----QYKQKNALIEQEIKIYTEMNLDGANINKKIEDLTHQISEE-KQLFE-QLIEE 1134

Query: 1104 MNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQS-A 1162
            + I K + ++I    + +                    L+ Q+++   Q+  V QE +  
Sbjct: 1135 LQIQKEQVLLIVPQKDEIQKLYLQTKQQYDQSVEDLSELQKQQQKVQDQKNQVTQEVNYL 1194

Query: 1163 KLNTELQECYTKIIQLETLNTELTGHDVVNQEQI--NQLKSKLEQLNTE---NDNLLSTV 1217
            KL TE QE   ++++L+ L  +L   D + QE    N ++ K +++  E   N   + T 
Sbjct: 1195 KLFTENQE--KQLVELQALRIKL--DDNIKQENTLKNAIQDKADRIQQELDRNKQAIQTQ 1250

Query: 1218 AELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELR-----VQLSAFESKYEQLL 1272
             ++    +   +QR  +I ++  +   Q+    + T+ +++      Q++  +   E+L+
Sbjct: 1251 IQILEKQNREKEQRQEQIQKIQTEIEDQKNNLNKLTDQQMKHLYQLDQIAKLDKDMERLM 1310

Query: 1273 DSV---QSSTQEETNKIVTMEQVTSLQ----NKLQDKEEHLRNLQEKYADVINQIEILRS 1325
              V   +   Q+    +   +Q  + Q    N+L+D+ +     +E+    I++ +   S
Sbjct: 1311 KDVFEKEEQVQQYAGLVYQKQQKVNDQKQKFNQLEDELKFYEREEEEIKKRISEQDEKLS 1370

Query: 1326 EIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQL---KKSSX 1382
            ++E E                    DL    +  +   E+ + N NE   +L   K+   
Sbjct: 1371 KLEREFQIRSEKRSKFEDEIAKAEMDLSNLEEMLRNRDEE-LRNFNESKVELMKFKQQYS 1429

Query: 1383 XXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLV 1442
                       ++ + E +  +L+ +++ +  ++ +   E   T  +  +    ++Q+L 
Sbjct: 1430 TIQGEIREKQEQIQEFEKQRSKLSEEIKKEQEQLTEINQEIYQTKVKEEEMNFQIQQKLK 1489

Query: 1443 EYE------KRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKIT 1496
            + +      ++++D     E+ + +   ++ +  +  ET++KE +I   +++E   VK  
Sbjct: 1490 DLDILNDQFRKLDDDAKMLEAVIQLKEKELKQYQDKKETLKKELDIANFQVVE---VK-- 1544

Query: 1497 ESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEI-TNLQNMVRASSSKIQ 1555
                LNK+  +  K +E +  +    + AL  Q   + T N  +  +LQ +V++ S  I 
Sbjct: 1545 --KQLNKK--KQQKPIEADNNEVEVYEDALSQQISCLNTKNLNLKDDLQRLVQSQSQPIF 1600

Query: 1556 KHVSFASDTKQGRDE-QLDNTMNKELLDAVPRAELDLAMY 1594
            + +     TK   +E QL      + LD + +    L+M+
Sbjct: 1601 QTMQQIEGTKTQLEELQLTIREKDKKLDILEQQLQQLSMH 1640



 Score =  134 bits (324), Expect = 2e-29
 Identities = 292/1524 (19%), Positives = 656/1524 (43%), Gaps = 135/1524 (8%)

Query: 144  VTHLSNTIKEKDNALSVL----QVKMKIMETTILDLQEKINEKDQIIEAK-NKATTXXXX 198
            +  L  TIK++++ +  L    Q K +IM  +     + +N+++Q +E++  +       
Sbjct: 413  IDQLKETIKQQESQIEFLKFEIQQKDEIMNMSQHTYLQDLNQQNQEVESRIQELKKQLSY 472

Query: 199  XXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANK 258
                         ED K +     +N   M+         L + +  K++ I  L E   
Sbjct: 473  KIKRKDQLESIVNEDQKPRRKSFVQNTELMD---------LQEQLHEKNMNIVQLYE--- 520

Query: 259  LLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEI 318
              E +RF+  L   +  QEL+Q              L K + E  CE+  E+ +K     
Sbjct: 521  --EISRFQKQLYDKE--QELQQRDVELRYQA-----LMKTN-EDQCEKADELVKKN---- 566

Query: 319  ANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNT 378
             +M EL   +E+   +  + +    E  N       ES   ++   K    I R SG N+
Sbjct: 567  LSMDELIHSLEV-RLVEKESKLKELEYLNSSKNFEIESNQNNNSFYKDRESIIRDSGINS 625

Query: 379  ASKMKSPWSQLSSETL---NQDTDKKINKNEIAKLEM-----VIQSLNKDLVD------K 424
              + +        + L   N   +   ++ E  K E+     +I+ L + L D       
Sbjct: 626  YDQDQDHQFVQQQQILAGFNSGLEHLKSRVECQKYELQEKDKIIEQLKQQLNDLKRSNFN 685

Query: 425  EYVISEKDTXXXXXXXXXXGK--DTLIAQ-LQLEHQQHMEGPSLIHVGTNTEDVNEIAK- 480
            + +++ +D            +  D L+ Q L LE   H     L       E+V +I + 
Sbjct: 686  QQILATQDVSVINRQINVLQEQADNLVKQNLALEDVIHELEYKLQEKKNKQEEVQQIIQN 745

Query: 481  -VQE--QLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKL 537
             ++E  QL+Q  +DE+   N+ +L EK++  E ++ Q   +     + + + + +   +L
Sbjct: 746  MMEEEVQLRQLKSDEMVKKNL-ELDEKIQQMESRLIQKQQQQYELEQRLSQHQRSMPQRL 804

Query: 538  K---QMQKTI-DNFSKVSDSNKEIVRLTEELHHLSQKVAELE---EEKGNLQLHLVDYDS 590
                + Q  I D+ S +S+   +I ++TE +  LSQ   ELE   ++K   Q  +     
Sbjct: 805  PVFHEDQDIIQDHNSNLSELTIQIAQITESVRQLSQDDIELEFLLKQKKEKQSQIEQLKL 864

Query: 591  GRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQ-QKYDEVEDKLAD--- 646
                 +DV +   ++++  + + + +  ++SQ  D+ Q ++ LQ Q+ + +ED       
Sbjct: 865  FIQSSTDVLQ---DLQSEQQIKQEQVEKMKSQNKDIEQMVNDLQNQQVNLIEDVNKSQQN 921

Query: 647  ----ISQ-LQSDQVCSEIKSVH--LEEQIDALSASKKELALVIENLKLDKEQLYGTIKDL 699
                ++Q ++S +  +E++     ++EQI  L +   +L +V++  + + +++      L
Sbjct: 922  VPNWLNQNMESSKRLNELQKGQQKVKEQIKNLESLILDLQIVVKEKQEELQRISQENYQL 981

Query: 700  ENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQF--GIDAKI 757
                     K  + ++E M L +K+  +  +++++L+A+ N   Q ++   F     AK 
Sbjct: 982  SILTRKQKQKRDHLLREQMPLGEKVGLLE-QQVNDLVAE-NKRLQLELARLFQEAESAKQ 1039

Query: 758  --QERDLYIENIESELSKYKSRICRLEESIA---VMEDRRYSLERKADQLGSYLQEKQKA 812
              Q ++  I  +  E S+    I  L++ I    ++E +    + +  Q  + ++++ K 
Sbjct: 1040 VKQTKEQQISALSIESSQLDQNIMLLKDDIEQAKILEQQLLDQQNQYKQKNALIEQEIKI 1099

Query: 813  YSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILL-EENQNLQISLSD 871
            Y+E  + +   +N+    + H    EKQL E   E  ++QK+  +L+  +   +Q     
Sbjct: 1100 YTEMNL-DGANINKKIEDLTHQISEEKQLFEQLIEELQIQKEQVLLIVPQKDEIQKLYLQ 1158

Query: 872  MQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITH--EHQTLIVQKKKEIEDLE 929
             +Q Y+  VE  +     + +    + Q+    + LK  T   E Q + +Q  +   D  
Sbjct: 1159 TKQQYDQSVEDLSELQKQQQKVQDQKNQVTQEVNYLKLFTENQEKQLVELQALRIKLDDN 1218

Query: 930  IEFNTQIESAIRDKKV-LNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLEL 988
            I+    +++AI+DK   + ++ ++N + + Q + Q+ E K N E      E++ K+  E+
Sbjct: 1219 IKQENTLKNAIQDKADRIQQELDRNKQAI-QTQIQILE-KQNREK-EQRQEQIQKIQTEI 1275

Query: 989  IDK--HVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINN-AQVSYMSM--V 1043
             D+  ++ K   Q   +  Q +++I KL+  +++  +++    +++   A + Y     V
Sbjct: 1276 EDQKNNLNKLTDQQMKHLYQ-LDQIAKLDKDMERLMKDVFEKEEQVQQYAGLVYQKQQKV 1334

Query: 1044 SDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFE 1103
            +D + K  Q   +L+  E E + + K++ +  +   +L+   + + ++  + ++     E
Sbjct: 1335 NDQKQKFNQLEDELKFYEREEEEIKKRISEQDEKLSKLEREFQIRSEKRSKFEDEIAKAE 1394

Query: 1104 MNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAK 1163
            M++   E M+ +   E  + + + V+             +++E++E IQE    ++Q +K
Sbjct: 1395 MDLSNLEEMLRNRDEELRNFNESKVELMKFKQQYSTIQGEIREKQEQIQE---FEKQRSK 1451

Query: 1164 LNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSS 1223
            L+ E+++   +  QL  +N E+    V  +E   Q++ KL+ L+  ND       + +  
Sbjct: 1452 LSEEIKK---EQEQLTEINQEIYQTKVKEEEMNFQIQQKLKDLDILNDQFRKLDDDAKM- 1507

Query: 1224 ISSAVDQRGFEIAELW-KQHLAQREADFQKTEH-ELRVQLSAFESKYEQLLDSVQSSTQE 1281
            + + +  +  E+ +   K+   ++E D    +  E++ QL+  + K ++ +++   + + 
Sbjct: 1508 LEAVIQLKEKELKQYQDKKETLKKELDIANFQVVEVKKQLN--KKKQQKPIEA--DNNEV 1563

Query: 1282 ETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVI----NQIEILRSEIEDEKVAFXXX 1337
            E  +    +Q++ L  K  + ++ L+ L +  +  I     QIE  ++++E+ ++     
Sbjct: 1564 EVYEDALSQQISCLNTKNLNLKDDLQRLVQSQSQPIFQTMQQIEGTKTQLEELQLTIREK 1623

Query: 1338 XXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVND 1397
                          L+  +    ++  QS    ++E   L+                +  
Sbjct: 1624 DKKLDILEQ----QLQQLSMHQSKVTIQSGFYFDDEPLLLELQDKFTKESEMLDD--LQQ 1677

Query: 1398 AEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKES 1457
               +  E  H+L LK  +  +K H+  I L QR       RQ + + EK +E L ++K+S
Sbjct: 1678 KLKRTAERHHELALKLQDWAEKEHKLAIELDQR-------RQCVEKIEKELEVL-FQKQS 1729

Query: 1458 ELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVA 1517
            +L   ++ + +     E   +E   + +  +  +  K      L K + E    ++E++ 
Sbjct: 1730 DLESDQVNLQQRMYQLELDNQELNEQEIISLNRIKEKKDYVQVLFKNLIE----MDEKLL 1785

Query: 1518 KTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMN 1577
            +          +  ++    + + N + M   S   IQ+ +  + + ++G  + +   + 
Sbjct: 1786 QLRNRMAVYSREGRQLAEQVENLENEKEMREESLQVIQEELE-SLELEKGEKQSMIQQIK 1844

Query: 1578 KELLDA-VPRAELDLAMYMLHQRD 1600
            KE+ D    + +L++   + H ++
Sbjct: 1845 KEIQDQNTEKDKLEIQYALTHSKN 1868



 Score =  111 bits (267), Expect = 2e-22
 Identities = 245/1276 (19%), Positives = 544/1276 (42%), Gaps = 113/1276 (8%)

Query: 149  NTIKEK-DNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXX 207
            N ++E+ DN +        ++      LQEK N+++++ +                    
Sbjct: 702  NVLQEQADNLVKQNLALEDVIHELEYKLQEKKNKQEEVQQIIQNMMEEEVQLRQLKSDEM 761

Query: 208  XXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEI 267
                 +  +++ +M+   I  + +  + +QRL +   S   R+    E   +++     +
Sbjct: 762  VKKNLELDEKIQQMESRLIQKQQQQYELEQRLSQHQRSMPQRLPVFHEDQDIIQDHNSNL 821

Query: 268  SLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKK 327
            S    ++AQ  E               L ++  + S  E+ ++  + S ++    +  ++
Sbjct: 822  SELTIQIAQITESVRQLSQDDIELEFLLKQKKEKQSQIEQLKLFIQSSTDVLQDLQSEQQ 881

Query: 328  I-----ELLEHLNCQIRQTNKELENKLATM--GTESKAVSSPSKKGSPLISRK---SGRN 377
            I     E ++  N  I Q   +L+N+   +         + P+     + S K     + 
Sbjct: 882  IKQEQVEKMKSQNKDIEQMVNDLQNQQVNLIEDVNKSQQNVPNWLNQNMESSKRLNELQK 941

Query: 378  TASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLN----KDLVDKEYVISEKDT 433
               K+K     L S  L+     K  + E+ ++      L+    K    +++++ E+  
Sbjct: 942  GQQKVKEQIKNLESLILDLQIVVKEKQEELQRISQENYQLSILTRKQKQKRDHLLREQMP 1001

Query: 434  XXXXXXXXXXGKDTLIAQ---LQLEHQQ-HMEGPSLIHVG-TNTEDVNEIAKVQEQLKQE 488
                        + L+A+   LQLE  +   E  S   V  T  + ++ ++    QL Q 
Sbjct: 1002 LGEKVGLLEQQVNDLVAENKRLQLELARLFQEAESAKQVKQTKEQQISALSIESSQLDQN 1061

Query: 489  LNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAAN---KNMIKVKSNHKLKLKQMQKTID 545
            +      + +KD IE+ K  E+Q+    ++    N   +  IK+ +   L    + K I+
Sbjct: 1062 I------MLLKDDIEQAKILEQQLLDQQNQYKQKNALIEQEIKIYTEMNLDGANINKKIE 1115

Query: 546  NFS-KVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQ-LHLV---DYDSGRMIESDVYK 600
            + + ++S+  +   +L EEL    ++V  +  +K  +Q L+L     YD      S++ K
Sbjct: 1116 DLTHQISEEKQLFEQLIEELQIQKEQVLLIVPQKDEIQKLYLQTKQQYDQSVEDLSELQK 1175

Query: 601  ---KMIEMENLAETRLKAISLL-ESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVC 656
               K+ + +N     +  + L  E+Q+  LV EL  L+ K D+      +I Q  + +  
Sbjct: 1176 QQQKVQDQKNQVTQEVNYLKLFTENQEKQLV-ELQALRIKLDD------NIKQENTLKNA 1228

Query: 657  SEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQE 716
             + K+  +++++D    + +    ++E    +KEQ    I+ ++ + ED  N L     +
Sbjct: 1229 IQDKADRIQQELDRNKQAIQTQIQILEKQNREKEQRQEQIQKIQTEIEDQKNNLNKLTDQ 1288

Query: 717  NMDLTDKLEKMSA-EKISELLAKINHEEQSKIQTQFGI----DAKIQERDLYIENIESEL 771
             M    +L++++  +K  E L K   E++ ++Q   G+      K+ ++      +E EL
Sbjct: 1289 QMKHLYQLDQIAKLDKDMERLMKDVFEKEEQVQQYAGLVYQKQQKVNDQKQKFNQLEDEL 1348

Query: 772  SKYKSRICRLEESIAVMEDRRYSLER----KADQLGSYLQEKQKAYSEYTIQEDELVNRL 827
              Y+     +++ I+  +++   LER    ++++   +  E  KA  + +  E+ L NR 
Sbjct: 1349 KFYEREEEEIKKRISEQDEKLSKLEREFQIRSEKRSKFEDEIAKAEMDLSNLEEMLRNRD 1408

Query: 828  AVLMD-HDRVVE-----KQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVE 881
              L + ++  VE     +Q   I+ E +E Q++ Q   ++   L   +   Q+    + +
Sbjct: 1409 EELRNFNESKVELMKFKQQYSTIQGEIREKQEQIQEFEKQRSKLSEEIKKEQEQLTEINQ 1468

Query: 882  KANRTDLAESEST-KYQTQLRDLE---SNLKRITHEHQTL--IVQ-KKKEIEDLEIEFNT 934
            +  +T + E E   + Q +L+DL+      +++  + + L  ++Q K+KE++  + +  T
Sbjct: 1469 EIYQTKVKEEEMNFQIQQKLKDLDILNDQFRKLDDDAKMLEAVIQLKEKELKQYQDKKET 1528

Query: 935  -QIESAIRDKKVLNEKYEKNIEYVTQ-LEAQLQEYKNNIENLNMNVEELNKMNLELIDKH 992
             + E  I + +V+  K + N +   + +EA   E +   + L+  +  LN  NL L D  
Sbjct: 1529 LKKELDIANFQVVEVKKQLNKKKQQKPIEADNNEVEVYEDALSQQISCLNTKNLNLKDDL 1588

Query: 993  VQKQQTQS-PDY-TEQYIN----EINKLNALLKQKDEEIIALNQKI-----NNAQVSYMS 1041
             +  Q+QS P + T Q I     ++ +L   +++KD+++  L Q++     + ++V+  S
Sbjct: 1589 QRLVQSQSQPIFQTMQQIEGTKTQLEELQLTIREKDKKLDILEQQLQQLSMHQSKVTIQS 1648

Query: 1042 -MVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVR---EQDDQIK-ELK 1096
                D E  L +   K     E +  + ++L  + + + EL + ++   E++ ++  EL 
Sbjct: 1649 GFYFDDEPLLLELQDKFTKESEMLDDLQQKLKRTAERHHELALKLQDWAEKEHKLAIELD 1708

Query: 1097 ETKLTFEMNIPKTEGMIISSTIEPMSDDAN--------NVDXXXXXXXXXXXXLKVQEEE 1148
            + +   E  I K   ++     +  SD  N         +D             +++E++
Sbjct: 1709 QRRQCVE-KIEKELEVLFQKQSDLESDQVNLQQRMYQLELDNQELNEQEIISLNRIKEKK 1767

Query: 1149 EFIQE--RSVLQ--EQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLE 1204
            +++Q   +++++  E+  +L   +     +  QL      L     + +E +  ++ +LE
Sbjct: 1768 DYVQVLFKNLIEMDEKLLQLRNRMAVYSREGRQLAEQVENLENEKEMREESLQVIQEELE 1827

Query: 1205 QLNTENDNLLSTVAELRSSI---SSAVDQRGFEIA------ELWKQHLAQREADFQKTEH 1255
             L  E     S + +++  I   ++  D+   + A      +  K  +   E+ ++K + 
Sbjct: 1828 SLELEKGEKQSMIQQIKKEIQDQNTEKDKLEIQYALTHSKNQQLKLFIGVEESLYKKMQT 1887

Query: 1256 ELRVQLSAFESKYEQLLDSVQSSTQEETNKI-VTMEQVTSLQNKLQDKEEHLRNLQ-EKY 1313
            E  +Q    +SKYE +     + T  E ++I V M+ +     K+  KE  L+ L+ E Y
Sbjct: 1888 EFEIQQKRDQSKYENMFVCNSTQTYYEVDQIEVLMDNLVG--QKITKKE--LQKLKTECY 1943

Query: 1314 ADVINQIEILRSEIED 1329
             ++       +S ++D
Sbjct: 1944 TEIQQLFAQNKSYVQD 1959



 Score =  110 bits (265), Expect = 3e-22
 Identities = 245/1261 (19%), Positives = 547/1261 (43%), Gaps = 151/1261 (11%)

Query: 396  QDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLE 455
            Q ++ K  KN I + EM+ Q +  + +D+  +++   +            + L +QLQ +
Sbjct: 33   QASEIKSLKNRINQKEMLSQPIFDNPIDQ--LLTYPKSLNALGLQIQEEFEKLKSQLQEK 90

Query: 456  HQQ-HM-----EGPSLIHVGTNTEDVNEIAKVQEQLKQ---ELNDEIKDVN-----VKDL 501
             Q+ H+     EG    +   NT  V+EI K  E++     EL  ++ D       ++ +
Sbjct: 91   EQELHLLRSGIEGQRRSYK-PNTTQVDEIIKQHEEIDDILIELEKKLYDKKQQKQELEQI 149

Query: 502  IEKLKSAEEQITQLNDEIDAANKNMIKVKSNH---KLKLKQMQKTIDNFSKVSDSNKEIV 558
            I      E+ + QL  +I   N+ ++  K+ +   +++LK++Q+   N       N ++ 
Sbjct: 150  INTYGDDEKILKQLKQQISVLNEQLVVEKAYNQEVRIQLKKLQQETQNL------NDQLE 203

Query: 559  RLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISL 618
                E      +VA+ + +   L+   +    G  ++ +  +K+I +++L +       L
Sbjct: 204  MKLAEKQDFEDQVAKTKSQLDYLKSQNIMLGIGTPVKGET-EKLIAIDDLVKQNQAVDDL 262

Query: 619  LESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKEL 678
            +   +  L+++    QQ ++++ D+L+     Q+ Q   +  S  L  Q  +LS  KKEL
Sbjct: 263  MNELQTKLLEK----QQAHNQLMDQLSK----QNIQENEQNSSTSLRPQ--SLSP-KKEL 311

Query: 679  ALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAK 738
               +E  + + E +   +K  + + E++ ++L+   QE   L  KL++    K+S +  +
Sbjct: 312  ISQLEVEQHECEIIQQQLKQKQLEIEELRDQLEKEEQEVFRLQYKLQEEIEVKVS-VEQQ 370

Query: 739  INHEEQSKIQTQFGIDAKIQER---DLYIENIESELSKYKSRICRLEESIAVMEDR---- 791
            I   +  ++  +  + + IQE    +++    ES    Y+ +I +L+E+I   E +    
Sbjct: 371  IQSVQSRQLIIEPTVTSYIQEAPTINVFGPQTESIPQDYQFQIDQLKETIKQQESQIEFL 430

Query: 792  RYSLERKADQLG----SYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEH- 846
            ++ +++K + +     +YLQ+  +   E   +  EL  +L+  +     +E  + E +  
Sbjct: 431  KFEIQQKDEIMNMSQHTYLQDLNQQNQEVESRIQELKKQLSYKIKRKDQLESIVNEDQKP 490

Query: 847  ------ENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQL 900
                  +N EL    + L E+N N+     ++ +    L +K       + E  +YQ  +
Sbjct: 491  RRKSFVQNTELMDLQEQLHEKNMNIVQLYEEISRFQKQLYDKEQELQQRDVE-LRYQALM 549

Query: 901  RDLES-------------NLKRITHEHQTLIVQKKKEIEDL---------EIE------- 931
            +  E              ++  + H  +  +V+K+ ++++L         EIE       
Sbjct: 550  KTNEDQCEKADELVKKNLSMDELIHSLEVRLVEKESKLKELEYLNSSKNFEIESNQNNNS 609

Query: 932  FNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDK 991
            F    ES IRD  + +   +++ ++V Q +  L  + + +E+L   V E  K  L+  DK
Sbjct: 610  FYKDRESIIRDSGINSYDQDQDHQFVQQQQI-LAGFNSGLEHLKSRV-ECQKYELQEKDK 667

Query: 992  HVQKQQTQSPDYTEQYINE----------INKLNALLKQKDEEIIALNQKINNAQVSYMS 1041
             +++ + Q  D      N+          IN+   +L+++ + ++  N  + +       
Sbjct: 668  IIEQLKQQLNDLKRSNFNQQILATQDVSVINRQINVLQEQADNLVKQNLALEDVIHELEY 727

Query: 1042 MVSDYESKLAQFTTKLEN-MEEEMQ--------RVSKQL-LDSKQHNEELQILVREQDDQ 1091
             + + ++K  +    ++N MEEE+Q         V K L LD K    E +++ ++Q  Q
Sbjct: 728  KLQEKKNKQEEVQQIIQNMMEEEVQLRQLKSDEMVKKNLELDEKIQQMESRLIQKQQ--Q 785

Query: 1092 IKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFI 1151
              EL++     + ++P+    +     + + D  +N+             ++   +++  
Sbjct: 786  QYELEQRLSQHQRSMPQ-RLPVFHEDQDIIQDHNSNLSELTIQIAQITESVRQLSQDDI- 843

Query: 1152 QERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTEND 1211
             E   L +Q  +  +++++    I     +  +L     + QEQ+ ++KS+    N + +
Sbjct: 844  -ELEFLLKQKKEKQSQIEQLKLFIQSSTDVLQDLQSEQQIKQEQVEKMKSQ----NKDIE 898

Query: 1212 NLLSTVAELRSSISSAVDQRGFEIAELWKQHL--AQREADFQKTEHELRVQLSAFESKYE 1269
             +++ +   + ++   V++    +     Q++  ++R  + QK + +++ Q+   ES   
Sbjct: 899  QMVNDLQNQQVNLIEDVNKSQQNVPNWLNQNMESSKRLNELQKGQQKVKEQIKNLESLIL 958

Query: 1270 QLLDSVQSSTQEETNKIVTME-QVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIE 1328
              L  V    QEE  +I     Q++ L  K + K +HL   Q    +   ++ +L  ++ 
Sbjct: 959  D-LQIVVKEKQEELQRISQENYQLSILTRKQKQKRDHLLREQMPLGE---KVGLLEQQVN 1014

Query: 1329 DEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXX 1388
            D                     +  +  Q  KQ +EQ I  ++ E++QL ++        
Sbjct: 1015 D----LVAENKRLQLELARLFQEAESAKQ-VKQTKEQQISALSIESSQLDQN----IMLL 1065

Query: 1389 XXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYT---ITLTQRNDEFENVRQQLVE-- 1443
                 +    E ++L+  +Q + K++ I Q+   YT   +     N + E++  Q+ E  
Sbjct: 1066 KDDIEQAKILEQQLLDQQNQYKQKNALIEQEIKIYTEMNLDGANINKKIEDLTHQISEEK 1125

Query: 1444 --YEKRIEDLTYEKESELAILRLKMHENANHYETMQK-ESEIERVKLIEELNVKITESVS 1500
              +E+ IE+L  +KE  L I+  K      + +T Q+ +  +E +  +++   K+ +   
Sbjct: 1126 QLFEQLIEELQIQKEQVLLIVPQKDEIQKLYLQTKQQYDQSVEDLSELQKQQQKVQD--Q 1183

Query: 1501 LNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEI---TNLQNMVRASSSKIQKH 1557
             N+   E+N     ++   N+ +  +E Q + I  L+D I     L+N ++  + +IQ+ 
Sbjct: 1184 KNQVTQEVNYL---KLFTENQEKQLVELQALRI-KLDDNIKQENTLKNAIQDKADRIQQE 1239

Query: 1558 V 1558
            +
Sbjct: 1240 L 1240



 Score = 99.1 bits (236), Expect = 9e-19
 Identities = 230/1208 (19%), Positives = 517/1208 (42%), Gaps = 139/1208 (11%)

Query: 468  VGTNTEDVNEIAKVQEQLKQELNDEIKD----VNVKDL---------IEKL----KSAEE 510
            V T  +D++ +   QE++  E   EIK     +N K++         I++L    KS   
Sbjct: 12   VSTQIQDLDSLISKQEKVINEQASEIKSLKNRINQKEMLSQPIFDNPIDQLLTYPKSLNA 71

Query: 511  QITQLNDEIDAANKNM-IKVKSNHKLKL---KQMQKTIDNFSKVSDSNKEIVRLTEELHH 566
               Q+ +E +     +  K +  H L+     Q +    N ++V +  K+   + + L  
Sbjct: 72   LGLQIQEEFEKLKSQLQEKEQELHLLRSGIEGQRRSYKPNTTQVDEIIKQHEEIDDILIE 131

Query: 567  LSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDL 626
            L +K+ + +++K  L+  +  Y     I   + K+ I + N      KA +  +  +  L
Sbjct: 132  LEKKLYDKKQQKQELEQIINTYGDDEKILKQL-KQQISVLNEQLVVEKAYN--QEVRIQL 188

Query: 627  VQELHILQQKYDEVEDKLADISQLQSDQVCSE------IKSVHLEEQIDALSASKKELAL 680
             +     Q   D++E KLA+    + DQV         +KS ++   I      + E  +
Sbjct: 189  KKLQQETQNLNDQLEMKLAEKQDFE-DQVAKTKSQLDYLKSQNIMLGIGTPVKGETEKLI 247

Query: 681  VIENLKLDKEQLYGTIKDLEN---DKEDIMNKLQNY-----IQEN-MDLTDKLEKMSAEK 731
             I++L    + +   + +L+    +K+   N+L +      IQEN  + +  L   S   
Sbjct: 248  AIDDLVKQNQAVDDLMNELQTKLLEKQQAHNQLMDQLSKQNIQENEQNSSTSLRPQSLSP 307

Query: 732  ISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDR 791
              EL++++   EQ + +    I  +++++ L IE +  +L K +  + RL+  +    + 
Sbjct: 308  KKELISQL-EVEQHECEI---IQQQLKQKQLEIEELRDQLEKEEQEVFRLQYKLQEEIEV 363

Query: 792  RYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRL-----AVLMDHD-------RVVEK 839
            + S+E++   + S     +   + Y IQE   +N       ++  D+          +++
Sbjct: 364  KVSVEQQIQSVQSRQLIIEPTVTSY-IQEAPTINVFGPQTESIPQDYQFQIDQLKETIKQ 422

Query: 840  QLLEIEHENKELQKKNQI-----------LLEENQNLQISLSDMQQHYNALVEKANRTDL 888
            Q  +IE    E+Q+K++I           L ++NQ ++  + ++++  +  +++ ++ + 
Sbjct: 423  QESQIEFLKFEIQQKDEIMNMSQHTYLQDLNQQNQEVESRIQELKKQLSYKIKRKDQLES 482

Query: 889  AESESTK-------YQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIR 941
              +E  K         T+L DL+  L    HE    IVQ  +EI      F  Q+    +
Sbjct: 483  IVNEDQKPRRKSFVQNTELMDLQEQL----HEKNMNIVQLYEEIS----RFQKQLYD--K 532

Query: 942  DKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEEL-NKMNLELIDKHVQKQQTQS 1000
            ++++     E   + + +      E  + +   N++++EL + + + L++K  + ++ + 
Sbjct: 533  EQELQQRDVELRYQALMKTNEDQCEKADELVKKNLSMDELIHSLEVRLVEKESKLKELEY 592

Query: 1001 PDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENM 1060
             + ++ +  E N+ N     KD E I  +  IN+            +  LA F + LE++
Sbjct: 593  LNSSKNFEIESNQNNNSF-YKDRESIIRDSGINSYDQDQDHQFVQQQQILAGFNSGLEHL 651

Query: 1061 EEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGM-IISSTIE 1119
            +    RV  Q    K   +E   ++ +   Q+ +LK +   F   I  T+ + +I+  I 
Sbjct: 652  K---SRVECQ----KYELQEKDKIIEQLKQQLNDLKRS--NFNQQILATQDVSVINRQIN 702

Query: 1120 PMSDDANNVDXXXXXXXXXXXXL--KVQE---EEEFIQE--RSVLQEQSAKLNTELQECY 1172
             + + A+N+             L  K+QE   ++E +Q+  +++++E+      +  E  
Sbjct: 703  VLQEQADNLVKQNLALEDVIHELEYKLQEKKNKQEEVQQIIQNMMEEEVQLRQLKSDEMV 762

Query: 1173 TKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSI---SSAVD 1229
             K ++L+    ++    +  Q+Q  +L+ +L Q        L    E +  I   +S + 
Sbjct: 763  KKNLELDEKIQQMESRLIQKQQQQYELEQRLSQHQRSMPQRLPVFHEDQDIIQDHNSNLS 822

Query: 1230 QRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQE----ETNK 1285
            +   +IA++  + + Q   D  + E  L+ Q    +S+ EQL   +QSST      ++ +
Sbjct: 823  ELTIQIAQI-TESVRQLSQDDIELEFLLK-QKKEKQSQIEQLKLFIQSSTDVLQDLQSEQ 880

Query: 1286 IVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQI--------EILRSEIEDEK-VAFXX 1336
             +  EQV  ++++ +D E+ + +LQ +  ++I  +          L   +E  K +    
Sbjct: 881  QIKQEQVEKMKSQNKDIEQMVNDLQNQQVNLIEDVNKSQQNVPNWLNQNMESSKRLNELQ 940

Query: 1337 XXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQL-------KKSSXXXXXXXX 1389
                           L  + Q   + +++ +  I++EN QL       K+          
Sbjct: 941  KGQQKVKEQIKNLESLILDLQIVVKEKQEELQRISQENYQLSILTRKQKQKRDHLLREQM 1000

Query: 1390 XXXXRVNDAEAKVLEL---THQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEK 1446
                +V   E +V +L     +L+L+ + ++Q+          +  +   +  +  + ++
Sbjct: 1001 PLGEKVGLLEQQVNDLVAENKRLQLELARLFQEAESAKQVKQTKEQQISALSIESSQLDQ 1060

Query: 1447 RIEDLTYEKESELAILRLKMHENANHYETMQKESEIER-VKLIEELNVKITESVSLNKQV 1505
             I  L  + E +  IL  ++ +  N Y+  QK + IE+ +K+  E+N+   +  ++NK++
Sbjct: 1061 NIMLLKDDIE-QAKILEQQLLDQQNQYK--QKNALIEQEIKIYTEMNL---DGANINKKI 1114

Query: 1506 AELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTK 1565
             +L   + EE     ++   L+ Q+ +++ +  +   +Q +   +  +  + V   S+ +
Sbjct: 1115 EDLTHQISEEKQLFEQLIEELQIQKEQVLLIVPQKDEIQKLYLQTKQQYDQSVEDLSELQ 1174

Query: 1566 QGRDEQLD 1573
            + + +  D
Sbjct: 1175 KQQQKVQD 1182



 Score = 97.5 bits (232), Expect = 3e-18
 Identities = 195/992 (19%), Positives = 431/992 (43%), Gaps = 109/992 (10%)

Query: 166  KIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENF 225
            KI+E  +LD Q +  +K+ +IE + K  T                 ED   Q+++ ++ F
Sbjct: 1073 KILEQQLLDQQNQYKQKNALIEQEIKIYTEMNLDGANINKKI----EDLTHQISEEKQLF 1128

Query: 226  IAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXX 285
              +  E + +K+++L  +  KD  I  L    K     +++ S+E     Q+ +Q     
Sbjct: 1129 EQLIEELQIQKEQVLLIVPQKD-EIQKLYLQTK----QQYDQSVEDLSELQKQQQKVQDQ 1183

Query: 286  XXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKEL 345
                       K   E    ++ ++ E  +L I     + ++  L   +  +  +  +EL
Sbjct: 1184 KNQVTQEVNYLKLFTE---NQEKQLVELQALRIKLDDNIKQENTLKNAIQDKADRIQQEL 1240

Query: 346  ENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKN 405
            +     + T+ + +   +++      ++  +   ++++   + L+  T +Q        +
Sbjct: 1241 DRNKQAIQTQIQILEKQNREKEQ--RQEQIQKIQTEIEDQKNNLNKLT-DQQMKHLYQLD 1297

Query: 406  EIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQ--LEHQQHMEGP 463
            +IAKL+  ++ L KD+ +KE  + +              +     QL+  L+  +  E  
Sbjct: 1298 QIAKLDKDMERLMKDVFEKEEQVQQYAGLVYQKQQKVNDQKQKFNQLEDELKFYEREEEE 1357

Query: 464  SLIHVGTNTEDVNEIAK---VQEQLKQELNDEIK--DVNVKDLIEKLKSAEEQITQLNDE 518
                +    E ++++ +   ++ + + +  DEI   ++++ +L E L++ +E++   N+ 
Sbjct: 1358 IKKRISEQDEKLSKLEREFQIRSEKRSKFEDEIAKAEMDLSNLEEMLRNRDEELRNFNE- 1416

Query: 519  IDAANKNMIKVKSNHKL---KLKQMQKTIDNFSKV-SDSNKEIVRLTEELHHLSQKV--A 572
               +   ++K K  +     ++++ Q+ I  F K  S  ++EI +  E+L  ++Q++   
Sbjct: 1417 ---SKVELMKFKQQYSTIQGEIREKQEQIQEFEKQRSKLSEEIKKEQEQLTEINQEIYQT 1473

Query: 573  ELEEEKGNLQLH--LVDYD-----------SGRMIESDVY---KKMIEMENLAETRLKAI 616
            +++EE+ N Q+   L D D             +M+E+ +    K++ + ++  ET  K +
Sbjct: 1474 KVKEEEMNFQIQQKLKDLDILNDQFRKLDDDAKMLEAVIQLKEKELKQYQDKKETLKKEL 1533

Query: 617  SLLESQKFDLVQELHIL-QQKYDEVEDKLADISQ-LQSDQV-CSEIKSVHLEEQIDALSA 673
             +   Q  ++ ++L+   QQK  E ++   ++ +   S Q+ C   K+++L++ +  L  
Sbjct: 1534 DIANFQVVEVKKQLNKKKQQKPIEADNNEVEVYEDALSQQISCLNTKNLNLKDDLQRLVQ 1593

Query: 674  SKKELALV----IENLKLDKEQLYGTIKDLENDKEDIMNKLQNY--------IQENMDLT 721
            S+ +        IE  K   E+L  TI++ +   + +  +LQ          IQ      
Sbjct: 1594 SQSQPIFQTMQQIEGTKTQLEELQLTIREKDKKLDILEQQLQQLSMHQSKVTIQSGFYFD 1653

Query: 722  DK---LEKMSA-EKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSR 777
            D+   LE      K SE+L  +  + +   +    +  K+Q+       +  EL + +  
Sbjct: 1654 DEPLLLELQDKFTKESEMLDDLQQKLKRTAERHHELALKLQDWAEKEHKLAIELDQRRQC 1713

Query: 778  ICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVV 837
            + ++E+ + V+  ++  LE     L   + + +    E   QE   +NR+    D+ +V+
Sbjct: 1714 VEKIEKELEVLFQKQSDLESDQVNLQQRMYQLELDNQELNEQEIISLNRIKEKKDYVQVL 1773

Query: 838  EKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQ 897
             K L+E++ +  +L+ +  +   E + L   + +++          N  ++ E      Q
Sbjct: 1774 FKNLIEMDEKLLQLRNRMAVYSREGRQLAEQVENLE----------NEKEMREESLQVIQ 1823

Query: 898  TQLRDLESNLKRITHEHQTLIVQKKKEIED-------LEIEF------NTQIESAIRDKK 944
             +L  LE  L++   E Q++I Q KKEI+D       LEI++      N Q++  I  ++
Sbjct: 1824 EELESLE--LEK--GEKQSMIQQIKKEIQDQNTEKDKLEIQYALTHSKNQQLKLFIGVEE 1879

Query: 945  VLNEKYEKNIEYVTQLEAQLQEYKN----NIENLNMNVEELNKMNLELIDKHVQKQQTQS 1000
             L +K +   E+  Q +    +Y+N    N       V+++  +   L+ + + K++ Q 
Sbjct: 1880 SLYKKMQ--TEFEIQQKRDQSKYENMFVCNSTQTYYEVDQIEVLMDNLVGQKITKKELQK 1937

Query: 1001 PDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTK---- 1056
               TE Y  EI +L A  K   ++ + +   I   Q+  +  V + E+ L    TK    
Sbjct: 1938 LK-TECY-TEIQQLFAQNKSYVQDNVNVRNLIQFQQI--LIQVVESENILLSEKTKCRKS 1993

Query: 1057 LENMEEEMQRVSKQLLDSKQHNEEL-QILVRE 1087
            L    EE    + +L+D+  ++  L +I + E
Sbjct: 1994 LTIQSEEQNTFTLELIDTIMNSSSLIEISINE 2025



 Score = 94.7 bits (225), Expect = 2e-17
 Identities = 208/1081 (19%), Positives = 463/1081 (42%), Gaps = 112/1081 (10%)

Query: 222  QENF--IAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELE 279
            QEN+    +  + K ++  LL++      ++  LE+    L A    + LE ++L QE E
Sbjct: 976  QENYQLSILTRKQKQKRDHLLREQMPLGEKVGLLEQQVNDLVAENKRLQLELARLFQEAE 1035

Query: 280  QXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIR 339
                           L   SIE S  ++  +  K  +E A + E     +LL+  N Q +
Sbjct: 1036 SAKQVKQTKEQQISAL---SIESSQLDQNIMLLKDDIEQAKILEQ----QLLDQQN-QYK 1087

Query: 340  QTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTD 399
            Q N  +E ++    TE                   G N   K++    Q+S E   Q  +
Sbjct: 1088 QKNALIEQEIKIY-TEMNL---------------DGANINKKIEDLTHQISEE--KQLFE 1129

Query: 400  KKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQH 459
            + I + +I K ++++    KD + K Y+ +++             K     Q +++ Q++
Sbjct: 1130 QLIEELQIQKEQVLLIVPQKDEIQKLYLQTKQQYDQSVEDLSELQKQ----QQKVQDQKN 1185

Query: 460  MEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEI 519
                 + ++   TE+  +     + L+ +L+D IK  N   L   ++   ++I Q  D  
Sbjct: 1186 QVTQEVNYLKLFTENQEKQLVELQALRIKLDDNIKQENT--LKNAIQDKADRIQQELDRN 1243

Query: 520  DAANKNMIKVKSNHKLKLKQMQKTIDNF-SKVSDSNKEIVRLTEE-LHHLSQ--KVAELE 575
              A +  I++      + +Q Q+ I    +++ D    + +LT++ + HL Q  ++A+L+
Sbjct: 1244 KQAIQTQIQILEKQNREKEQRQEQIQKIQTEIEDQKNNLNKLTDQQMKHLYQLDQIAKLD 1303

Query: 576  EEKGNLQLHLVDYDSG-RMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQ 634
            ++   L   + + +   +     VY+K    + + + + K   L +  KF   +E  I +
Sbjct: 1304 KDMERLMKDVFEKEEQVQQYAGLVYQKQ---QKVNDQKQKFNQLEDELKFYEREEEEI-K 1359

Query: 635  QKYDEVEDKLADIS---QLQSDQVCS---EIKSVHLE-EQIDALSASKKELALVIENLKL 687
            ++  E ++KL+ +    Q++S++      EI    ++   ++ +  ++ E        K+
Sbjct: 1360 KRISEQDEKLSKLEREFQIRSEKRSKFEDEIAKAEMDLSNLEEMLRNRDEELRNFNESKV 1419

Query: 688  DK---EQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQ 744
            +    +Q Y TI+    +K++   ++Q + ++   L+++++K   E+++E+  +I   + 
Sbjct: 1420 ELMKFKQQYSTIQGEIREKQE---QIQEFEKQRSKLSEEIKK-EQEQLTEINQEIYQTKV 1475

Query: 745  SKIQTQFGIDAKIQERDLY---IENIESELSKYKSRICRLEESIAVMEDRRYSLERKAD- 800
             + +  F I  K+++ D+       ++ +    ++ I   E+ +   +D++ +L+++ D 
Sbjct: 1476 KEEEMNFQIQQKLKDLDILNDQFRKLDDDAKMLEAVIQLKEKELKQYQDKKETLKKELDI 1535

Query: 801  ----------QLGSYLQEK--QKAYSEYTIQEDELVNRLAVLM--------DHDRVVEKQ 840
                      QL    Q+K  +   +E  + ED L  +++ L         D  R+V+ Q
Sbjct: 1536 ANFQVVEVKKQLNKKKQQKPIEADNNEVEVYEDALSQQISCLNTKNLNLKDDLQRLVQSQ 1595

Query: 841  -------LLEIEHENKELQKKNQILLEENQNLQISLSDMQQ---HYNALVEKA-----NR 885
                   + +IE    +L++    + E+++ L I    +QQ   H + +  ++     + 
Sbjct: 1596 SQPIFQTMQQIEGTKTQLEELQLTIREKDKKLDILEQQLQQLSMHQSKVTIQSGFYFDDE 1655

Query: 886  TDLAESES--TKYQTQLRDLESNLKRITHEHQTLIVQKKKEIED---LEIEFNTQIESAI 940
              L E +   TK    L DL+  LKR    H  L ++ +   E    L IE + + +   
Sbjct: 1656 PLLLELQDKFTKESEMLDDLQQKLKRTAERHHELALKLQDWAEKEHKLAIELDQRRQCVE 1715

Query: 941  RDKKVLNEKYEKNIEYVT-QLEAQLQEYKNNIENLNMNVEELNKMN-LELIDKHVQKQQT 998
            + +K L   ++K  +  + Q+  Q + Y+  ++N  +N +E+  +N ++    +VQ    
Sbjct: 1716 KIEKELEVLFQKQSDLESDQVNLQQRMYQLELDNQELNEQEIISLNRIKEKKDYVQVLFK 1775

Query: 999  QSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLE 1058
               +  E+ +   N++ A+  ++  ++    + + N +      +   + +L     +  
Sbjct: 1776 NLIEMDEKLLQLRNRM-AVYSREGRQLAEQVENLENEKEMREESLQVIQEELESLELEKG 1834

Query: 1059 NMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTI 1118
              +  +Q++ K++ D     ++L+I       + ++LK   +  E ++ K   M     I
Sbjct: 1835 EKQSMIQQIKKEIQDQNTEKDKLEIQYALTHSKNQQLK-LFIGVEESLYKK--MQTEFEI 1891

Query: 1119 EPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQ-ECYTKIIQ 1177
            +   D +   +            +   ++ E + +  V Q+ + K   +L+ ECYT+I Q
Sbjct: 1892 QQKRDQSKYENMFVCNSTQTYYEV---DQIEVLMDNLVGQKITKKELQKLKTECYTEIQQ 1948

Query: 1178 LETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAE 1237
            L   N      D VN   + Q +  L Q+    + LLS   + R S++   +++     E
Sbjct: 1949 LFAQNKSYV-QDNVNVRNLIQFQQILIQVVESENILLSEKTKCRKSLTIQSEEQNTFTLE 2007

Query: 1238 L 1238
            L
Sbjct: 2008 L 2008



 Score = 82.2 bits (194), Expect = 1e-13
 Identities = 188/955 (19%), Positives = 417/955 (43%), Gaps = 101/955 (10%)

Query: 706  IMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIE 765
            ++  +   IQ+   L  K EK+  E+ SE+ +  N   Q ++ +Q   D  I +   Y +
Sbjct: 8    LLKVVSTQIQDLDSLISKQEKVINEQASEIKSLKNRINQKEMLSQPIFDNPIDQLLTYPK 67

Query: 766  NIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVN 825
            ++ + L        +++E    ++ +    E++   L S ++ ++++Y   T Q DE++ 
Sbjct: 68   SLNA-LG------LQIQEEFEKLKSQLQEKEQELHLLRSGIEGQRRSYKPNTTQVDEIIK 120

Query: 826  RLAVLMDHDRVVEKQLLEIEHENKEL---------------QKKNQI-LLEE-------- 861
            +   + D    +EK+L + + + +EL               Q K QI +L E        
Sbjct: 121  QHEEIDDILIELEKKLYDKKQQKQELEQIINTYGDDEKILKQLKQQISVLNEQLVVEKAY 180

Query: 862  NQNLQISLSDMQQHYNAL-----VEKANRTDLAESESTKYQTQLRDLES-NL-----KRI 910
            NQ ++I L  +QQ    L     ++ A + D  E +  K ++QL  L+S N+       +
Sbjct: 181  NQEVRIQLKKLQQETQNLNDQLEMKLAEKQDF-EDQVAKTKSQLDYLKSQNIMLGIGTPV 239

Query: 911  THEHQTLI-----VQKKKEIEDLEIEFNTQ-IESAIRDKKVLNEKYEKNIE-----YVTQ 959
              E + LI     V++ + ++DL  E  T+ +E      +++++  ++NI+       T 
Sbjct: 240  KGETEKLIAIDDLVKQNQAVDDLMNELQTKLLEKQQAHNQLMDQLSKQNIQENEQNSSTS 299

Query: 960  LEAQ-LQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALL 1018
            L  Q L   K  I  L +   E   +  +L  K ++ ++ +  D  E+   E+ +L   L
Sbjct: 300  LRPQSLSPKKELISQLEVEQHECEIIQQQLKQKQLEIEELR--DQLEKEEQEVFRLQYKL 357

Query: 1019 KQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHN 1078
            +++ E  +++ Q+I + Q S   ++    +   Q    +     + + + +   D +   
Sbjct: 358  QEEIEVKVSVEQQIQSVQ-SRQLIIEPTVTSYIQEAPTINVFGPQTESIPQ---DYQFQI 413

Query: 1079 EELQILVREQDDQIKELKETKLTFEMNIPKTEGMIIS--STIEPMSDDANNVDXXXXXXX 1136
            ++L+  +++Q+ QI+ LK     FE+   K E M +S  + ++ ++     V+       
Sbjct: 414  DQLKETIKQQESQIEFLK-----FEIQ-QKDEIMNMSQHTYLQDLNQQNQEVE-SRIQEL 466

Query: 1137 XXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQI 1196
                  K++ +++   E  V ++Q  +  + +Q   T+++ L+    E   + V   E+I
Sbjct: 467  KKQLSYKIKRKDQL--ESIVNEDQKPRRKSFVQN--TELMDLQEQLHEKNMNIVQLYEEI 522

Query: 1197 NQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHE 1256
            ++ +   +QL  +   L     ELR       ++   E A+     L ++     +  H 
Sbjct: 523  SRFQ---KQLYDKEQELQQRDVELRYQALMKTNEDQCEKAD----ELVKKNLSMDELIHS 575

Query: 1257 LRVQLSAFESKYEQL--LDSVQS----STQEETNKIVTMEQV---TSLQNKLQDKEEHLR 1307
            L V+L   ESK ++L  L+S ++    S Q   +     E +   + + +  QD++    
Sbjct: 576  LEVRLVEKESKLKELEYLNSSKNFEIESNQNNNSFYKDRESIIRDSGINSYDQDQDHQFV 635

Query: 1308 NLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSI 1367
              Q+  A   + +E L+S +E +K                   DL+  N + + +  Q +
Sbjct: 636  QQQQILAGFNSGLEHLKSRVECQKYEL-QEKDKIIEQLKQQLNDLKRSNFNQQILATQDV 694

Query: 1368 LNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITL 1427
              IN +   L++ +             +++ E K+ E  ++ E +  +I Q   E  + L
Sbjct: 695  SVINRQINVLQEQADNLVKQNLALEDVIHELEYKLQEKKNKQE-EVQQIIQNMMEEEVQL 753

Query: 1428 TQ-RNDEFENVRQQLVEYEKRIEDLTYEKESELAIL--RLKMHENA--NHYETMQKESEI 1482
             Q ++DE      +L E  +++E    +K+ +   L  RL  H+ +         ++ +I
Sbjct: 754  RQLKSDEMVKKNLELDEKIQQMESRLIQKQQQQYELEQRLSQHQRSMPQRLPVFHEDQDI 813

Query: 1483 --ERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEI 1540
              +    + EL ++I +     +Q+++ +  LE  + +  E Q+ +E  ++ I +  D +
Sbjct: 814  IQDHNSNLSELTIQIAQITESVRQLSQDDIELEFLLKQKKEKQSQIEQLKLFIQSSTDVL 873

Query: 1541 TNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDLAMYM 1595
             +LQ+  +    +++K  S   D +Q  ++  +  +N  L++ V +++ ++  ++
Sbjct: 874  QDLQSEQQIKQEQVEKMKSQNKDIEQMVNDLQNQQVN--LIEDVNKSQQNVPNWL 926


>UniRef50_UPI00006CD8D3 Cluster: hypothetical protein TTHERM_00522610;
            n=1; Tetrahymena thermophila SB210|Rep: hypothetical
            protein TTHERM_00522610 - Tetrahymena thermophila SB210
          Length = 1547

 Score =  134 bits (325), Expect = 1e-29
 Identities = 231/1235 (18%), Positives = 537/1235 (43%), Gaps = 94/1235 (7%)

Query: 370  ISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIA----KLEMVIQSLNKDLVDK- 424
            IS KS      +M++  +Q   +  NQD  +   ++        +   I++L ++ +++ 
Sbjct: 12   ISYKSSDQDKQQMQNIQAQQDLQQNNQDQSQSNGQSNSQFTPQDVAFYIENLKRNYLERL 71

Query: 425  ---EYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHM----EGPSLIHVGTNTEDVNE 477
               E + S K+            K+ L    Q E + ++    E  S++ +     +  +
Sbjct: 72   EGDEVIDSLKNDPELESFRVERFKEILKQSFQYEQELYIDKMIEANSMLKLDLKKSEEEK 131

Query: 478  IAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKL 537
              ++ EQ K E+ +  K V   +   + ++A++ + Q   E     KN+ K   +  LK+
Sbjct: 132  YIEI-EQAKIEIQNISKKVLEFESAIQQEAAQKMVLQNEYEKLLKQKNLEKANYDELLKI 190

Query: 538  KQMQKT-IDNFSK--VSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMI 594
            K+  +T  D+  K  + +S  EI  L +E  +L  +  +++++   L  +L  Y      
Sbjct: 191  KESSQTKQDSMYKQELQNSRMEIESLLKEKSNLQIQNEQMKDQIDTLTKNLQIYSQKHQA 250

Query: 595  ESD---VY-KKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQL 650
             S+   +Y +K  EM+N+ +     I  LES   + +++LH+  Q+   ++  LA+ +Q 
Sbjct: 251  RSETDRIYEQKNEEMKNIIQKLQTQIVDLESSNENCIEQLHLKDQEIQVIKTSLAE-TQK 309

Query: 651  QSDQVCSEIKSVHLE-EQIDALSASKK-ELALVIENLKLDKEQLYGTIKDLENDKEDIMN 708
            ++D + +  + + ++  ++++L   K  EL+  +E ++  K+ L    K+  N  + I  
Sbjct: 310  ENDYLSNNTEKLKVQIAKLESLVNEKSGELSKKLEKVRSKKKAL----KEKFNQNKQI-- 363

Query: 709  KLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIE 768
             L+N+ +E       +++  AE+    +  +   +   I+ ++       E++  I  + 
Sbjct: 364  -LENHSREISQYKKNIQE-QAEQYERTIQGMK-GDMLTIKNEWEKRCNEVEKECQI-LVN 419

Query: 769  SELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLA 828
               +KY+ +  ++++    + D++    ++ D+  + L   +   S+   +  ++     
Sbjct: 420  QSKTKYEMQAQKIKQEYQQLLDKKM---QELDESTNQLNFSKGFNSQIQTKIQQIEKDYI 476

Query: 829  VLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDL 888
            +   H++++E ++ ++E +++EL   NQI      N+Q  + ++        E+ +R   
Sbjct: 477  LKEQHEKILEGEIAKLEAKHQEL--INQISEIHQNNIQAKIKEIS-------ERKSRE-- 525

Query: 889  AESESTKYQTQLRDLESNLK---RITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKV 945
             E+ S   Q    DL++ L+   ++T +++  I++ +     ++ E N Q    I  K +
Sbjct: 526  YETLSQGLQNNCLDLQAKLQDQIKLTAQYKEKILEVENNFYKIKDEINQQ-NQYINVKLL 584

Query: 946  LNEKYEKNIEYV--TQLEAQLQEYKN---NIENLNMNVEELNKMNLELIDKHVQKQQTQS 1000
               K + N+ Y    QL+ Q +E+ N   N+EN  +N ++ +  ++    K V++   + 
Sbjct: 585  GFFKLQINLSYFMKKQLKGQNEEHINHRKNLENKILNYQQ-DLEDIRNSKKQVEEALQEQ 643

Query: 1001 PDYTEQYINEINKLNALLK---QKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKL 1057
             + ++     I KL   L+   QK+E+    N+++ N      ++   YES+      +L
Sbjct: 644  LELSQMQSESIQKLQTNLEEYNQKEEQWQNENEELQN------NLQQQYESQ-ESLKRQL 696

Query: 1058 ENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISST 1117
            E ++++ +   +  + + Q  E +++   ++ ++ +E K+  L  E  + + +       
Sbjct: 697  EQIKQKQEVEKQSAIRNVQFQESIKL--EKEKEEHEETKQKLLQLERKVKQVQ-KEQEKI 753

Query: 1118 IEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSA---KLNTELQE-CYT 1173
             E   +    +             L+ ++++  IQ   + Q+  A   K+N + Q  C  
Sbjct: 754  NEDYEERLQQMQEKSIKISGQKEKLETEKKDLIIQVNEIQQKYEAFTSKINRDKQRICKR 813

Query: 1174 KIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGF 1233
              +QL++L  +L+  D+ N  Q++   +K+ +++ +   ++ ++    +     +++   
Sbjct: 814  LGLQLKSLKDDLS--DIQNDSQLD--IAKIYEVSKQ--TIVQSIDHFNNLKQREINKLEN 867

Query: 1234 EIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVT 1293
            +  +  ++ L +     ++ E  LR Q ++     + ++D ++S  ++  +KI ++    
Sbjct: 868  QFRQNQEEILNEFNEKMEQIEENLRNQANSTNVDLQNIIDQLKSENEQLQDKISSLLASQ 927

Query: 1294 SLQNKLQDK-EEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDL 1352
             L  K + K E  L NL EK+ + +  I    SE  +E   F                 L
Sbjct: 928  ELIEKEKKKLESQLSNL-EKHNEKLEGIIKRNSEDMEEHNKFFAAEIKRIKDESNSLVQL 986

Query: 1353 RTENQSYKQMQEQSILNINEENAQ-LKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLE- 1410
              ++      QE  IL       Q + + +             +   E  + EL  Q E 
Sbjct: 987  AVDSALQSSKQEIDILQKKIATLQSMNEKAKAKEDTIYDLNREIQQREGNIDELQKQFEQ 1046

Query: 1411 ---LKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMH 1467
               +KD EI QK       L     E +++ +++ E   +  ++    E +L   +  + 
Sbjct: 1047 NMKIKDEEI-QKKENLIEKLRAELQEMQHIYEKMQEENNQAFEVL---EKKLENYKQAIS 1102

Query: 1468 ENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALE 1527
              A  Y+ ++++S +E   L EEL + + + ++  +Q  + N A  +E+ +T   ++ L 
Sbjct: 1103 SEAQKYQMVKEQSNLEIQSLNEELEI-VRQQLATKEQNID-NLAKYQEL-QTYSKRSQLP 1159

Query: 1528 NQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFAS 1562
             Q I+    N++ T  Q            H++  S
Sbjct: 1160 QQFIQNQLQNNQTTQAQQTHNLPPQPPSSHLNTTS 1194



 Score = 87.0 bits (206), Expect = 4e-15
 Identities = 153/754 (20%), Positives = 314/754 (41%), Gaps = 69/754 (9%)

Query: 388  QLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDT 447
            QL  +       +K  +N+I   +  ++ +       E  + E+               T
Sbjct: 600  QLKGQNEEHINHRKNLENKILNYQQDLEDIRNSKKQVEEALQEQLELSQMQSESIQKLQT 659

Query: 448  LIAQL-QLEHQQHMEGPSLIHVGTNTEDVNEIAKVQ-EQLKQ----ELNDEIKDVNVKDL 501
             + +  Q E Q   E   L +      +  E  K Q EQ+KQ    E    I++V  ++ 
Sbjct: 660  NLEEYNQKEEQWQNENEELQNNLQQQYESQESLKRQLEQIKQKQEVEKQSAIRNVQFQES 719

Query: 502  IEKLKSAEE------QITQLNDEIDAANKNMIKVKSNHKLKLKQMQ-KTIDNFSKVSDSN 554
            I+  K  EE      ++ QL  ++    K   K+  +++ +L+QMQ K+I    +     
Sbjct: 720  IKLEKEKEEHEETKQKLLQLERKVKQVQKEQEKINEDYEERLQQMQEKSIKISGQKEKLE 779

Query: 555  KEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLK 614
             E   L  +++ + QK  E    K N     +    G  ++S +   + +++N  +++L 
Sbjct: 780  TEKKDLIIQVNEIQQKY-EAFTSKINRDKQRICKRLGLQLKS-LKDDLSDIQN--DSQLD 835

Query: 615  AISLLESQKFDLVQEL-HILQQKYDEVEDKLADISQLQSDQVCSEI--KSVHLEEQI-DA 670
               + E  K  +VQ + H    K  E+ +KL +  +   +++ +E   K   +EE + + 
Sbjct: 836  IAKIYEVSKQTIVQSIDHFNNLKQREI-NKLENQFRQNQEEILNEFNEKMEQIEENLRNQ 894

Query: 671  LSASKKELALVIENLKLDKEQLYGTIKDL-------ENDKEDIMNKLQNYIQENMDLTDK 723
             +++  +L  +I+ LK + EQL   I  L       E +K+ + ++L N  + N  L + 
Sbjct: 895  ANSTNVDLQNIIDQLKSENEQLQDKISSLLASQELIEKEKKKLESQLSNLEKHNEKL-EG 953

Query: 724  LEKMSAEKISE----LLAKINH-EEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRI 778
            + K ++E + E      A+I   +++S    Q  +D+ +Q     I+ ++ +++  +S  
Sbjct: 954  IIKRNSEDMEEHNKFFAAEIKRIKDESNSLVQLAVDSALQSSKQEIDILQKKIATLQS-- 1011

Query: 779  CRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVE 838
              + E     ED  Y L R+  Q    + E QK + +    +DE + +   L++  R   
Sbjct: 1012 --MNEKAKAKEDTIYDLNREIQQREGNIDELQKQFEQNMKIKDEEIQKKENLIEKLRA-- 1067

Query: 839  KQLLEIEHENKELQKKN----QILLEENQNLQISLSDMQQHYNALVEKANRTDLAESEST 894
             +L E++H  +++Q++N    ++L ++ +N + ++S   Q Y  + E++N    + +E  
Sbjct: 1068 -ELQEMQHIYEKMQEENNQAFEVLEKKLENYKQAISSEAQKYQMVKEQSNLEIQSLNEEL 1126

Query: 895  KY-QTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKN 953
            +  + QL   E N+  +    +     K+ ++    I+   Q     + ++  N   +  
Sbjct: 1127 EIVRQQLATKEQNIDNLAKYQELQTYSKRSQLPQQFIQNQLQNNQTTQAQQTHNLPPQPP 1186

Query: 954  IEYVTQLEAQLQEYKNNIE----NLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQY-- 1007
              ++    +    ++NN +      + +     K N    +    +Q   S  +   +  
Sbjct: 1187 SSHLNTTSSVFSTHRNNQQYPQQQTSYSAVRTLKQNNSASNLIATQQNNNSSSFNISHQP 1246

Query: 1008 -------INEINKLNALLKQ-KDEEIIALNQKINN--------AQVSYMSMVSDYESKLA 1051
                   I  +N LN   K  K E    LNQ   +        A  SY+   S  +S  A
Sbjct: 1247 GNNSASKIQNVNYLNYNEKPVKLEATNQLNQASTHQTQFYKYQADKSYVKQYSLDKSFDA 1306

Query: 1052 QFTTKLENMEEEMQRVSKQLLDSKQHNEELQILV 1085
            Q    L ++  + + VS+  L S+Q N +  + V
Sbjct: 1307 QRLDTLSDLSRQHKIVSQAKLASQQQNSQASLSV 1340


>UniRef50_A0EEQ9 Cluster: Chromosome undetermined scaffold_92, whole
            genome shotgun sequence; n=3; Paramecium tetraurelia|Rep:
            Chromosome undetermined scaffold_92, whole genome shotgun
            sequence - Paramecium tetraurelia
          Length = 1107

 Score =  134 bits (325), Expect = 1e-29
 Identities = 217/1047 (20%), Positives = 450/1047 (42%), Gaps = 84/1047 (8%)

Query: 502  IEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVS-DSNKEIVRL 560
            IE LK AE Q   L  +    N+N       H+L++KQ+ + I N+ + + D   ++ + 
Sbjct: 78   IEFLKQAEAQSKMLTTQFQEMNQN-------HQLEVKQLLEQIQNYKQRNVDLKSQVEQY 130

Query: 561  TEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLK-AISLL 619
              EL+  + K  E   E+     +  +Y      + D+ K  ++ ++     LK  I  +
Sbjct: 131  MTELNKSNLKYQECCRERDEYLKNFREYSQ----DYDIMKMQLQGKDAEIVSLKDRIHNI 186

Query: 620  E-SQKFDLVQELHILQQ-KYDEVEDKLADIS-QLQSDQVCSEIKSVHLEEQIDALSASKK 676
            E S + +L Q     +  K   ++ ++ +I+ Q   D++ S+IK  +LE +   L     
Sbjct: 187  ESSHQQELTQYSQTNEHWKRSLMDTQIKEITQQFNQDRIQSDIKIKNLENKNIELENKCV 246

Query: 677  ELALVIENLKL-DKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMS--AEKIS 733
             LA  +E +++ D EQ     K+L+N+  ++  K+Q  +Q      +++ +M    ++  
Sbjct: 247  LLAQEMERMRVKDLEQNKVVNKNLQNENNELKAKIQEMMQFITRYEEQINEMEFYQDQDQ 306

Query: 734  ELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRY 793
            +   KI        +    I+ + Q+   Y + I+  L +Y+ +   LEE   +    + 
Sbjct: 307  KDRMKIVVLSSEIERLHCVIEEQQQQTQSYQQQIQG-LEQYEMQCQLLEEQQLLNNQLKE 365

Query: 794  SLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQK 853
             L+++ ++  + LQ+++    E+T++  EL ++ A+L       E + L +   N +   
Sbjct: 366  QLDQEVEKNQNTLQQQEYYQQEWTVRNQELQDKCAML-----TTELERLNLVTRNNDRSS 420

Query: 854  KNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHE 913
            +N     E ++LQ     ++ H+  + EK+N     E E + YQ +   L S+   +   
Sbjct: 421  RN--YQYEIESLQ---KQLENHFQIVEEKSNIILQLEMEISNYQQESMLLNSDNDNLNMR 475

Query: 914  HQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNI-- 971
                I Q ++EI++++ + + Q     ++ +   E Y   +   T    Q  + K ++  
Sbjct: 476  ----ITQLEEEIQEIKDQASQQQSRRSQELRQQIEYYANELNRTTYNYNQANQDKESLHQ 531

Query: 972  --ENLNMNVEEL----NKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQK--DE 1023
              E +N   ++L     + ++E+ D + Q Q  +     E  INE+ K    L++   D+
Sbjct: 532  EYEKINREYKDLFFTSQQKDIEIKDLYDQIQLIRDKHQIE--INELKKQGEYLRRSVLDQ 589

Query: 1024 EIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQI 1083
            +I  L +K NN + ++     D + +  Q + +   M+  M    +Q L   Q+  + Q+
Sbjct: 590  QIRDLTEKFNNDKQAF-----DMQFRQLQQSKQQVEMQNSM---LQQNLQELQYTVDGQL 641

Query: 1084 LVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLK 1143
             ++ Q  Q  E +   L  E+   + E   +S+    M +D                 L 
Sbjct: 642  EIQRQKLQTSEKERINLLQEIKDYQMELQRVSNERFQMKEDFVKERMKIVIYATEIDRL- 700

Query: 1144 VQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKL 1203
                E+F  +    +EQ+   N ++Q+         TL T+   H+ ++  ++ + K+ L
Sbjct: 701  WSVIEDFTNQIKKTEEQNRLQNDQIQQL--------TLTTQ-QYHNTISTLELEK-KNHL 750

Query: 1204 EQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSA 1263
             + N +  +L + +  + + +    +Q   E + +++Q + Q+    Q+ E EL  Q+ +
Sbjct: 751  RENNMKEQSLENKMIVMTNELERTKNQLYEEQSRVYEQEIKQKSL-LQEIE-ELYQQIES 808

Query: 1264 FESKYEQL----LDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQ 1319
            ++S+   +    L+     T+ +  ++    Q   L N++QD E+ +  L ++   +   
Sbjct: 809  YQSEITIMQKNGLEVGDLETKFQAERMSWETQKYQLNNQIQDYEQRVHLLSQEIKRLTTI 868

Query: 1320 IEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKK 1379
             +    EIE+ +  F                DL  E Q  +   EQS L +      L+K
Sbjct: 869  GDERLHEIEELRFKFRDASLAENYEQLKTEYDL-LEQQVME--LEQSNLKLKSHTQTLEK 925

Query: 1380 SSXXXXXXXXXXXXRVNDAEAKVLELTHQLEL--KDSEIYQKTHEYTITLTQRNDEFENV 1437
                           V D    + +   Q E   K++E  +KT +    L Q        
Sbjct: 926  QIQLLELSLQDKSREVEDIYNLMNKQRRQSESTNKEAENNRKTQQ---QLQQTISNLGQQ 982

Query: 1438 RQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEI-ERVKLIEELNVKIT 1496
             QQL E  + + +     +S++  ++  +HE     +  +K SE+ E++K I+ L VK  
Sbjct: 983  NQQLKEQLQTVNNENQSLQSQIQYMQNSLHERDQMIQ--KKSSELTEKIKEIDSLKVKYE 1040

Query: 1497 ESV--SLNKQVAELNKALEEEVAKTNE 1521
            + +  S+ +     N ++  +V KT++
Sbjct: 1041 QKMNNSIIQSTVIRNSSITRQVIKTDQ 1067



 Score = 96.3 bits (229), Expect = 6e-18
 Identities = 189/932 (20%), Positives = 386/932 (41%), Gaps = 104/932 (11%)

Query: 704  EDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKIN----HEEQSKIQTQFGIDAKIQE 759
            + ++ ++QNY Q N+DL  ++E+   E     L         +E  K   ++  D  I +
Sbjct: 107  KQLLEQIQNYKQRNVDLKSQVEQYMTELNKSNLKYQECCRERDEYLKNFREYSQDYDIMK 166

Query: 760  RDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLER---KADQLGSYLQEKQKAYSEY 816
              L  +  ++E+   K RI  +E S    E  +YS      K   + + ++E  + +++ 
Sbjct: 167  MQL--QGKDAEIVSLKDRIHNIESSHQ-QELTQYSQTNEHWKRSLMDTQIKEITQQFNQD 223

Query: 817  TIQEDELVNRLA---VLMDHDRVVEKQLLEIEHENKELQKK--NQILLEENQNLQISLSD 871
             IQ D  +  L    + +++  V+  Q +E        Q K  N+ L  EN  L+  + +
Sbjct: 224  RIQSDIKIKNLENKNIELENKCVLLAQEMERMRVKDLEQNKVVNKNLQNENNELKAKIQE 283

Query: 872  MQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKR---ITHEHQTLIVQKKKEIEDL 928
            M Q      E+ N  +  + +  K + ++  L S ++R   +  E Q      +++I+ L
Sbjct: 284  MMQFITRYEEQINEMEFYQDQDQKDRMKIVVLSSEIERLHCVIEEQQQQTQSYQQQIQGL 343

Query: 929  E-IEFNTQI--ESAIRD---KKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLN----MNV 978
            E  E   Q+  E  + +   K+ L+++ EKN   + Q E   QE+    + L     M  
Sbjct: 344  EQYEMQCQLLEEQQLLNNQLKEQLDQEVEKNQNTLQQQEYYQQEWTVRNQELQDKCAMLT 403

Query: 979  EELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVS 1038
             EL ++NL  + ++  +         E    ++     ++++K   I+ L  +I+N Q  
Sbjct: 404  TELERLNL--VTRNNDRSSRNYQYEIESLQKQLENHFQIVEEKSNIILQLEMEISNYQQE 461

Query: 1039 YMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKET 1098
             M + SD ++       ++  +EEE+Q +  Q   S+Q +   Q L ++ +    EL  T
Sbjct: 462  SMLLNSDNDN----LNMRITQLEEEIQEIKDQA--SQQQSRRSQELRQQIEYYANELNRT 515

Query: 1099 KLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQ 1158
              T+  N    +   +    E ++ +    D              + ++ + I+++  ++
Sbjct: 516  --TYNYNQANQDKESLHQEYEKINREYK--DLFFTSQQKDIEIKDLYDQIQLIRDKHQIE 571

Query: 1159 EQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVA 1218
                K   E         Q+  L  +          Q  QL+   +Q+  +N  L   + 
Sbjct: 572  INELKKQGEYLRRSVLDQQIRDLTEKFNNDKQAFDMQFRQLQQSKQQVEMQNSMLQQNLQ 631

Query: 1219 ELRSSISSAVD--QRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESK--------- 1267
            EL+ ++   ++  ++  + +E  + +L Q   D+Q      RV    F+ K         
Sbjct: 632  ELQYTVDGQLEIQRQKLQTSEKERINLLQEIKDYQMELQ--RVSNERFQMKEDFVKERMK 689

Query: 1268 ---YEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEI-- 1322
               Y   +D + S  ++ TN+I   E+   LQN   D+ + L    ++Y + I+ +E+  
Sbjct: 690  IVIYATEIDRLWSVIEDFTNQIKKTEEQNRLQN---DQIQQLTLTTQQYHNTISTLELEK 746

Query: 1323 ---LRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQ-MQEQSILNINEENAQLK 1378
               LR     E+                       +++ Y+Q ++++S+L   EE  Q  
Sbjct: 747  KNHLRENNMKEQSLENKMIVMTNELERTKNQLYEEQSRVYEQEIKQKSLLQEIEELYQQI 806

Query: 1379 KSSXXXXXXXXXXXXRVNDAEAKV-----------LELTHQLELKDSEIY---QKTHEYT 1424
            +S              V D E K             +L +Q++  +  ++   Q+    T
Sbjct: 807  ESYQSEITIMQKNGLEVGDLETKFQAERMSWETQKYQLNNQIQDYEQRVHLLSQEIKRLT 866

Query: 1425 ITLTQRNDEFENVR-----QQLVE-YE--KRIEDLTYEKESELAILRLKMHENANHYETM 1476
                +R  E E +R       L E YE  K   DL  ++  EL    LK+    +H +T+
Sbjct: 867  TIGDERLHEIEELRFKFRDASLAENYEQLKTEYDLLEQQVMELEQSNLKLK---SHTQTL 923

Query: 1477 QKESEIERVKL------IEEL----NVKITESVSLNKQVAELNKALEEEVAKTNEMQTAL 1526
            +K+ ++  + L      +E++    N +  +S S NK+ AE N+  ++++ +T       
Sbjct: 924  EKQIQLLELSLQDKSREVEDIYNLMNKQRRQSESTNKE-AENNRKTQQQLQQTIS-NLGQ 981

Query: 1527 ENQEI--EIVTLNDEITNLQNMVRASSSKIQK 1556
            +NQ++  ++ T+N+E  +LQ+ ++   + + +
Sbjct: 982  QNQQLKEQLQTVNNENQSLQSQIQYMQNSLHE 1013



 Score = 76.6 bits (180), Expect = 5e-12
 Identities = 166/827 (20%), Positives = 336/827 (40%), Gaps = 108/827 (13%)

Query: 743  EQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQL 802
            E+   + +F   A+ Q + L  +  E     ++  + +L E I   + R   L+ + +Q 
Sbjct: 72   EEKNREIEFLKQAEAQSKMLTTQFQEMN-QNHQLEVKQLLEQIQNYKQRNVDLKSQVEQY 130

Query: 803  GSYLQEKQKAYSEYTIQEDE-LVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEE 861
             + L +    Y E   + DE L N      D+D +++ QL   + E   L+ +   +   
Sbjct: 131  MTELNKSNLKYQECCRERDEYLKNFREYSQDYD-IMKMQLQGKDAEIVSLKDRIHNIESS 189

Query: 862  NQNLQISLSDMQQHYN-ALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQ-TLIV 919
            +Q      S   +H+  +L++   +    +    + Q+ ++      K I  E++  L+ 
Sbjct: 190  HQQELTQYSQTNEHWKRSLMDTQIKEITQQFNQDRIQSDIKIKNLENKNIELENKCVLLA 249

Query: 920  QKKKEIEDLEIEFNTQIESAIRDKK-VLNEKYEKNIEYVTQLEAQLQE---YKNNIENLN 975
            Q+ + +   ++E N  +   ++++   L  K ++ ++++T+ E Q+ E   Y++  +   
Sbjct: 250  QEMERMRVKDLEQNKVVNKNLQNENNELKAKIQEMMQFITRYEEQINEMEFYQDQDQKDR 309

Query: 976  MNVEELNKMNLELIDKHVQKQQTQSPDYT------EQY------INEINKLNALLKQKDE 1023
            M +  L+   +E +   +++QQ Q+  Y       EQY      + E   LN  LK++ +
Sbjct: 310  MKIVVLSS-EIERLHCVIEEQQQQTQSYQQQIQGLEQYEMQCQLLEEQQLLNNQLKEQLD 368

Query: 1024 EIIALNQKINNAQVSYMSMVS----DYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNE 1079
            + +  NQ     Q  Y    +    + + K A  TT+LE +    +   +   + +   E
Sbjct: 369  QEVEKNQNTLQQQEYYQQEWTVRNQELQDKCAMLTTELERLNLVTRNNDRSSRNYQYEIE 428

Query: 1080 ELQILVREQDDQIKELKETKLTFEMNIP--KTEGMIISSTIEPMSDDANNVDXXXXXXXX 1137
             LQ  +      ++E     L  EM I   + E M+++S       D +N++        
Sbjct: 429  SLQKQLENHFQIVEEKSNIILQLEMEISNYQQESMLLNS-------DNDNLN-------- 473

Query: 1138 XXXXLKVQEEEEFIQE-RSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQI 1196
                +++ + EE IQE +    +Q ++ + EL++          LN     ++  NQ++ 
Sbjct: 474  ----MRITQLEEEIQEIKDQASQQQSRRSQELRQQIE--YYANELNRTTYNYNQANQDK- 526

Query: 1197 NQLKSKLEQLNTENDNLLST-------VAELRSSISSAVDQRGFEIAELWKQHLAQREAD 1249
              L  + E++N E  +L  T       + +L   I    D+   EI EL KQ    R + 
Sbjct: 527  ESLHQEYEKINREYKDLFFTSQQKDIEIKDLYDQIQLIRDKHQIEINELKKQGEYLRRSV 586

Query: 1250 FQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNL 1309
              +   +L  + +  +  ++     +Q S Q+             +QN +  +     NL
Sbjct: 587  LDQQIRDLTEKFNNDKQAFDMQFRQLQQSKQQ-----------VEMQNSMLQQ-----NL 630

Query: 1310 QEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILN 1369
            QE    V  Q+EI R +++  +                   +L  E + Y QM+ Q + N
Sbjct: 631  QELQYTVDGQLEIQRQKLQTSE---------------KERINLLQEIKDY-QMELQRVSN 674

Query: 1370 INEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQ 1429
               E  Q+K+               ++   + + + T+Q++        KT E       
Sbjct: 675  ---ERFQMKEDFVKERMKIVIYATEIDRLWSVIEDFTNQIK--------KTEEQN---RL 720

Query: 1430 RNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIE 1489
            +ND+ + +     +Y   I  L  EK++ L    +K     N    M  E E  + +L E
Sbjct: 721  QNDQIQQLTLTTQQYHNTISTLELEKKNHLRENNMKEQSLENKMIVMTNELERTKNQLYE 780

Query: 1490 ELNVKITESV---SLNKQVAELNKALEEEVAKTNEMQ-TALENQEIE 1532
            E +    + +   SL +++ EL + +E   ++   MQ   LE  ++E
Sbjct: 781  EQSRVYEQEIKQKSLLQEIEELYQQIESYQSEITIMQKNGLEVGDLE 827



 Score = 74.1 bits (174), Expect = 3e-11
 Identities = 157/856 (18%), Positives = 349/856 (40%), Gaps = 67/856 (7%)

Query: 144  VTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXX 203
            + +L N   E +N   +L  +M+ M    L+  + +N+  Q    + KA           
Sbjct: 231  IKNLENKNIELENKCVLLAQEMERMRVKDLEQNKVVNKNLQNENNELKAKIQEMMQFITR 290

Query: 204  XXXXXXXXEDTKQQMTKMQENFIAMEAEWK------DEKQRLLKDIESKDVRISSLEEAN 257
                    E  + Q  K +   + + +E +      +E+Q+  +  + +   +   E   
Sbjct: 291  YEEQINEMEFYQDQDQKDRMKIVVLSSEIERLHCVIEEQQQQTQSYQQQIQGLEQYEMQC 350

Query: 258  KLLEAARFEISLEHSKLAQELE--QXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGS 315
            +LLE  +   +    +L QE+E  Q              +  Q ++  C   T   E+ +
Sbjct: 351  QLLEEQQLLNNQLKEQLDQEVEKNQNTLQQQEYYQQEWTVRNQELQDKCAMLTTELERLN 410

Query: 316  LEIANMTELTKKIEL-LEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKS 374
            L   N    ++  +  +E L  Q+    + +E K   +      +S+  ++   L S   
Sbjct: 411  LVTRNNDRSSRNYQYEIESLQKQLENHFQIVEEKSNIILQLEMEISNYQQESMLLNSDND 470

Query: 375  GRNTA-SKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDT 433
              N   ++++    ++  +   Q + +     +  ++E     LN+   +      +K++
Sbjct: 471  NLNMRITQLEEEIQEIKDQASQQQSRRSQELRQ--QIEYYANELNRTTYNYNQANQDKES 528

Query: 434  XXXXXXXXXXG-KDTLIAQLQ--LEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELN 490
                        KD      Q  +E +   +   LI      E +NE+ K  E L++ + 
Sbjct: 529  LHQEYEKINREYKDLFFTSQQKDIEIKDLYDQIQLIRDKHQIE-INELKKQGEYLRRSVL 587

Query: 491  DEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKV 550
            D+     ++DL EK  + ++       ++  + + +    S  +  L+++Q T+D     
Sbjct: 588  DQ----QIRDLTEKFNNDKQAFDMQFRQLQQSKQQVEMQNSMLQQNLQELQYTVDG---- 639

Query: 551  SDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEM-ENLA 609
                 EI R         QK+   E+E+ NL   + DY   +M    V  +  +M E+  
Sbjct: 640  ---QLEIQR---------QKLQTSEKERINLLQEIKDY---QMELQRVSNERFQMKEDFV 684

Query: 610  ETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCS-EIKSVHLEEQI 668
            + R+K +  + + + D +    +++   ++++ K  + ++LQ+DQ+    + +      I
Sbjct: 685  KERMKIV--IYATEIDRLWS--VIEDFTNQIK-KTEEQNRLQNDQIQQLTLTTQQYHNTI 739

Query: 669  DALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMS 728
              L   KK   L   N+K  ++ L   +  + N+ E   N+L  Y +++     ++++ S
Sbjct: 740  STLELEKKN-HLRENNMK--EQSLENKMIVMTNELERTKNQL--YEEQSRVYEQEIKQKS 794

Query: 729  A-EKISELLAKI-NHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIA 786
              ++I EL  +I +++ +  I  + G++    E     E +  E  KY+     L   I 
Sbjct: 795  LLQEIEELYQQIESYQSEITIMQKNGLEVGDLETKFQAERMSWETQKYQ-----LNNQIQ 849

Query: 787  VMEDRRYSLERKADQLGSYLQEKQKAYSE--YTIQEDELVNRLAVLMDHDRVVEKQLLEI 844
              E R + L ++  +L +   E+     E  +  ++  L      L     ++E+Q++E+
Sbjct: 850  DYEQRVHLLSQEIKRLTTIGDERLHEIEELRFKFRDASLAENYEQLKTEYDLLEQQVMEL 909

Query: 845  EHENKELQKKNQILLEENQNLQISLSDMQQH----YNALVEKANRTDLAESEST---KYQ 897
            E  N +L+   Q L ++ Q L++SL D  +     YN + ++  +++    E+    K Q
Sbjct: 910  EQSNLKLKSHTQTLEKQIQLLELSLQDKSREVEDIYNLMNKQRRQSESTNKEAENNRKTQ 969

Query: 898  TQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYV 957
             QL+   SNL +   + +  +     E + L+ +      S     +++ +K  +  E +
Sbjct: 970  QQLQQTISNLGQQNQQLKEQLQTVNNENQSLQSQIQYMQNSLHERDQMIQKKSSELTEKI 1029

Query: 958  TQLEAQLQEYKNNIEN 973
             ++++   +Y+  + N
Sbjct: 1030 KEIDSLKVKYEQKMNN 1045


>UniRef50_Q3V6T2 Cluster: Girdin; n=53; Euteleostomi|Rep: Girdin -
            Homo sapiens (Human)
          Length = 1871

 Score =  134 bits (325), Expect = 1e-29
 Identities = 227/1096 (20%), Positives = 448/1096 (40%), Gaps = 75/1096 (6%)

Query: 475  VNEIAKVQEQLKQELND-EIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNH 533
            V+++     + K+ L+D E     V++L E  +   E  T L D+++       K+    
Sbjct: 322  VDKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELE 381

Query: 534  KLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRM 593
            K  L+   K  D   +     K+I  L EE   L     +  +E  +L   L        
Sbjct: 382  KENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTSE 441

Query: 594  IESDVYKKM-IEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQS 652
            +     K +  E+  L  +RL     LE +   L + +  L+   D VE   + I +++ 
Sbjct: 442  LSEAPQKSLGHEVNELTSSRLLK---LEMENQSLTKTVEELRTTVDSVEGNASKILKMEK 498

Query: 653  DQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQN 712
            +      K   LE +I     S +    + ++L  +K QL  TI+ L  + E  +  L+ 
Sbjct: 499  ENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILE- 557

Query: 713  YIQENMDLTDKLEKMSAEKISELLAKINH-EEQSKI--QTQFGIDAKIQERDLYIENIES 769
              QEN  L   +  +         A++   E+++KI  ++     +K+ + +     I+ 
Sbjct: 558  --QENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKK 615

Query: 770  ELSKYKS---RICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNR 826
            EL  YK    R   LE  +  +E     L++K   L     EK +A  +   + +    +
Sbjct: 616  ELEHYKEKGERAEELENELHHLEKENELLQKKITNL-KITCEKIEALEQENSELERENRK 674

Query: 827  LAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRT 886
            L   +D  + +  QL  +E EN +L ++N  L    ++L+ +   M Q     ++  N+ 
Sbjct: 675  LKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQ-----LQLENKE 729

Query: 887  DLAESESTKYQTQLRDLE-SNLKRITHEHQTLIVQKKKEIEDLEIEFNT--QIESAIRDK 943
              +E E  K   +L        +R+   +Q L ++ ++  + LE       Q+ES ++D 
Sbjct: 730  LESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDL 789

Query: 944  KVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQ-KQQTQSPD 1002
            ++ N+  +KN+E +     +L++ +   ++L     +L K   +L  ++ + +QQ +  D
Sbjct: 790  EMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKD 849

Query: 1003 YTEQY----INEINKLNALLKQK----DEEIIALNQK-------INNAQVSYMSMVSDYE 1047
             T +     I  + K N  L ++     E  + L +        +  A +   ++V+  E
Sbjct: 850  TTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLRE 909

Query: 1048 SKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKL--TFEMN 1105
              +++   K + M  ++++++ +L     + E L    +  DD   +L E+KL  T + +
Sbjct: 910  DLVSE-KLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLESKLESTLKKS 968

Query: 1106 IPKTEGMI--ISSTIEPMSDDANNVDXXXXXXXXXXXXLKV-QEEEEFIQERSVLQEQSA 1162
            +   E  I  + + +E  ++    +             LK  Q+EE  +Q    +  +  
Sbjct: 969  LEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGEDN 1028

Query: 1163 KLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRS 1222
            K   E QE   ++++++    E+  ++   Q +   LK++L+QL T+N+NL + +  L+ 
Sbjct: 1029 KWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQR 1088

Query: 1223 SISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEE 1282
               S  +Q            L  + A  Q     L  Q ++  ++  QLL    S   E 
Sbjct: 1089 QTVSLQEQ---------NTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENEN 1139

Query: 1283 TNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXX 1342
             + I   E + SL + L    E L  L E+ A   ++ E L S+    K A         
Sbjct: 1140 ESVIKEREDLKSLYDSLIKDHEKLELLHERQA---SEYESLISKHGTLKSAHKNLEVEHR 1196

Query: 1343 XXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKV 1402
                     L+ + Q  + +++  +L + +E   L+  +              ND     
Sbjct: 1197 DLEDRYNQLLKQKGQ-LEDLEK--MLKVEQEKMLLENKNHETVAAEYKKLCGENDR---- 1249

Query: 1403 LELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAIL 1462
            L  T+   LK++E+ Q  H+   +L   N + E  R +  E+ K       E+  +L I 
Sbjct: 1250 LNHTYSQLLKETEVLQTDHKNLKSLL-NNSKLEQTRLE-AEFSK-----LKEQYQQLDIT 1302

Query: 1463 RLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEE----VAK 1518
              K++        ++   E E   L++++   + ++ +L +Q  E       E    + K
Sbjct: 1303 STKLNNQCELLSQLKGNLEEENRHLLDQIQTLMLQNRTLLEQNMESKDLFHVEQRQYIDK 1362

Query: 1519 TNEMQTALENQEIEIV 1534
             NE++   E  E +I+
Sbjct: 1363 LNELRRQKEKLEEKIM 1378



 Score =  112 bits (269), Expect = 9e-23
 Identities = 226/1099 (20%), Positives = 472/1099 (42%), Gaps = 95/1099 (8%)

Query: 479  AKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLK 538
            AK++ +L+QEL +  K   + D  ++L+  E ++ +L  E    N N++    + ++   
Sbjct: 258  AKIR-RLRQELEE--KTEQLLDCKQELEQMEIELKRLQQE----NMNLLSDARSARMYRD 310

Query: 539  QMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQL------HLVDYDSGR 592
            ++    +   +V     E+ R  E LH +    A +EE K + Q+       L D   G 
Sbjct: 311  ELDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGT 370

Query: 593  MIESDVYKKMIEMENL-AETRLKAISL---LESQKF-DLVQELHILQ----QKYDEVEDK 643
               SD   + +E ENL  + +L  + +   ++ +K  +L++E   L+    Q  DE    
Sbjct: 371  RARSDKLHE-LEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHL 429

Query: 644  LADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDK--EQLYGTIKDLEN 701
              ++ Q+      SE     L  +++ L++S+  L L +EN  L K  E+L  T+  +E 
Sbjct: 430  GWELEQISRTSELSEAPQKSLGHEVNELTSSRL-LKLEMENQSLTKTVEELRTTVDSVEG 488

Query: 702  DKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQS------KIQTQFGIDA 755
            +   I+ K++   +EN  L+ K+E +  E + E  +  N +  S      K Q +  I+ 
Sbjct: 489  NASKIL-KME---KENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIET 544

Query: 756  KIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRY-SLERKADQLGSYLQEKQKAYS 814
              +  +  I+ +E E       +  L +   +  + R   +E++   L   ++E     S
Sbjct: 545  LRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLS 604

Query: 815  EYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQ- 873
            +   ++ ++   L    +H +   ++  E+E+E   L+K+N++L ++  NL+I+   ++ 
Sbjct: 605  KIEFEKRQIKKEL----EHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEA 660

Query: 874  -QHYNALVEKANRTDLAESESTKYQT-QLRDLESNLKRITHEHQTL--IVQKKK----EI 925
             +  N+ +E+ NR      +S K  T QL  LE    ++  E+  L   V+  K    ++
Sbjct: 661  LEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKM 720

Query: 926  EDLEIEFNTQIESAIRDKK----VLNEKYEK--NIEYVTQ-LEAQLQEYKNNIENLNMNV 978
              L++E N ++ES     K    +L   ++K   +E   Q L+ + Q  +  +EN N  +
Sbjct: 721  AQLQLE-NKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKI 779

Query: 979  EELNK--MNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQ 1036
            ++L     +LE+ ++ +QK   +    + + + ++ K N  L+Q+  ++    +++    
Sbjct: 780  QQLESELQDLEMENQTLQK-NLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKEN 838

Query: 1037 VSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELK 1096
                      ++ L +   K+ N+E+E + +SK++   K+    L+ L +E  + +   K
Sbjct: 839  KRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELV---K 895

Query: 1097 ETKLTFEMNIPKTEGMIISS-TIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERS 1155
               +  +  +   E ++      + M++D   +             L   E+        
Sbjct: 896  RATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYK 955

Query: 1156 VLQ---EQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDN 1212
            +L+   E + K + E++E   KI  LE    E T ++   ++++  +K   E L    D 
Sbjct: 956  LLESKLESTLKKSLEIKE--EKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDE 1013

Query: 1213 LLSTVAELRSSISSAVDQRGFEIAELWKQHL--AQREADFQKTEHELRVQLSAFESKYEQ 1270
                + +    IS   ++   E  E  ++ L    R  + ++    L+ +  A +++ +Q
Sbjct: 1014 --ERMVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQ 1071

Query: 1271 L---LDSVQSSTQEETNKIVTM-EQVTSLQN---KLQDKEEHLRNLQEKYADVINQIEIL 1323
            L    +++Q+       + V++ EQ T+LQ    KLQ +   L +      +   Q+ I 
Sbjct: 1072 LETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQ 1131

Query: 1324 RSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXX 1383
            +S +E+E  +                 D   + +   + Q     ++  ++  LK +   
Sbjct: 1132 QSSLENENESVIKEREDLKSLYDSLIKD-HEKLELLHERQASEYESLISKHGTLKSAHKN 1190

Query: 1384 XXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVE 1443
                      R N    ++L+   QLE  D E   K  +  + L  +N E      + + 
Sbjct: 1191 LEVEHRDLEDRYN----QLLKQKGQLE--DLEKMLKVEQEKMLLENKNHETVAAEYKKLC 1244

Query: 1444 YEKRIEDLTYE---KESELAIL---RLKMHENANHYETMQKESEIERVK-LIEELNVKIT 1496
             E    + TY    KE+E+       LK   N +  E  + E+E  ++K   ++L++  T
Sbjct: 1245 GENDRLNHTYSQLLKETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITST 1304

Query: 1497 ESVSLNKQVAELNKALEEE 1515
            +  +  + +++L   LEEE
Sbjct: 1305 KLNNQCELLSQLKGNLEEE 1323



 Score =  106 bits (255), Expect = 4e-21
 Identities = 181/868 (20%), Positives = 388/868 (44%), Gaps = 72/868 (8%)

Query: 295  LAKQSIEPSCEE-KTEIE--EKGSLEIANMTE----LTKKIELLEHLNCQIRQT------ 341
            +  QS+  + EE +T ++  E  + +I  M +    L+KK+E+LE+   Q +Q+      
Sbjct: 467  MENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQN 526

Query: 342  -NKELENKLATMGTESKAVSSPSKKGSPLISRKSG--RNTASKMKSPWSQLSSETLNQDT 398
             +K+L  + A +    + +   S++   ++ +++     T S ++   SQ+S+E   +D 
Sbjct: 527  LSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQR-SQISAEARVKDI 585

Query: 399  DKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQ 458
            +K+ NK     ++     L+K   +K  +  E +            ++ L     LE + 
Sbjct: 586  EKE-NKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENEL---HHLEKEN 641

Query: 459  HMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDV--NVKDLIEKLKSAEEQITQLN 516
             +    + ++    E +  + +   +L++E N ++K    + K+L  +L+S E++ +QL+
Sbjct: 642  ELLQKKITNLKITCEKIEALEQENSELERE-NRKLKKTLDSFKNLTFQLESLEKENSQLD 700

Query: 517  DEIDAANKNMIKVKSNHKLKLKQMQ---KTIDNFSKVSDSNKEIVRLT-EELHHLSQKVA 572
            +E     +N+  +K    +K+ Q+Q   K +++  +      E+++ + ++   L     
Sbjct: 701  EENLELRRNVESLKC-ASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQ 759

Query: 573  ELEEEKGNLQLHLVDYDSG-RMIESDVYKKMIEMEN-LAETRLKAISLLESQKFDLVQEL 630
             L+ E   LQ  L + +   + +ES++  + +EMEN   +  L+ + +   +   L +E 
Sbjct: 760  GLDIENQRLQKTLENSNKKIQQLESEL--QDLEMENQTLQKNLEELKISSKRLEQLEKEN 817

Query: 631  HILQQKYDEVE-DKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDK 689
              L+Q+  ++E DK     + +  +  +EIK   LEE    +   +KE   + + + + K
Sbjct: 818  KSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYK 877

Query: 690  EQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKL--EKMSAEKISELLAKINHE-EQSK 746
            E     +K+LE + ++++ +    I+  + L + L  EK+  ++++  L K+ HE E+  
Sbjct: 878  ESCV-RLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIG 936

Query: 747  IQTQFGIDAKIQERDLYIENIESEL-SKYKSRICRLEESIAVMEDRRYSLERKADQLGSY 805
            +  +  +  +    D   + +ES+L S  K  +   EE IA +E R         QL   
Sbjct: 937  LNKERLLHDEQSTDDSRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQE 996

Query: 806  LQEKQKAYSEYTIQEDE--LVNRLAVLMDHDRVVE-------KQLLEIEHENKELQKKNQ 856
            L+  +K Y     ++DE  +V     +   D   E       ++LL+++    E+++ N 
Sbjct: 997  LKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVERNNA 1056

Query: 857  ILLEENQNLQISLSDMQQHYNAL----VEKANRTDLAESESTKYQTQLRDLESNLKRITH 912
             L  E Q L+  L  ++   N L    +    +T   + ++T  QTQ   L+     + +
Sbjct: 1057 TLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTL-N 1115

Query: 913  EHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQL----EAQLQEYK 968
               T ++ +  ++   +     + ES I++++ L   Y+  I+   +L    E Q  EY+
Sbjct: 1116 SQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYE 1175

Query: 969  NNIE---NLNMNVEELNKMNLELIDKHVQ--KQQTQSPDYTEQYINEINKLNALLKQKDE 1023
            + I     L    + L   + +L D++ Q  KQ+ Q  D  +    E  K+  LL+ K+ 
Sbjct: 1176 SLISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKM--LLENKNH 1233

Query: 1024 EIIAL--------NQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSK 1075
            E +A         N ++N+     +      ++      + L N + E  R+  +    K
Sbjct: 1234 ETVAAEYKKLCGENDRLNHTYSQLLKETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLK 1293

Query: 1076 QHNEELQILVREQDDQIKELKETKLTFE 1103
            +  ++L I   + ++Q + L + K   E
Sbjct: 1294 EQYQQLDITSTKLNNQCELLSQLKGNLE 1321



 Score =  105 bits (253), Expect = 8e-21
 Identities = 193/906 (21%), Positives = 386/906 (42%), Gaps = 77/906 (8%)

Query: 689  KEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAE--KISELLAKINHEEQSK 746
            ++ L   + D +     +  +L+   ++ +D   +LE+M  E  ++ +    +  + +S 
Sbjct: 246  RQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSA 305

Query: 747  IQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYL 806
               +  +DA ++E+ + ++ +ESE+S+YK R+  +E   A +E      E K D     L
Sbjct: 306  RMYRDELDA-LREKAVRVDKLESEVSRYKERLHDIEFYKARVE------ELKEDN--QVL 356

Query: 807  QEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQ 866
             E +    +         ++L  L   +  ++ +L ++E E    +KK + L+EEN  L+
Sbjct: 357  LETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLE 416

Query: 867  ISLS---DMQQHYNALVEKANRT-DLAESESTKYQTQLRDLESN-LKRITHEHQTLI--V 919
            ++     D   H    +E+ +RT +L+E+       ++ +L S+ L ++  E+Q+L   V
Sbjct: 417  MAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTV 476

Query: 920  QKKKEIEDLEIEFN-TQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKN--------- 969
            ++ +   D  +E N ++I    ++ + L++K E     + Q +  LQ  +N         
Sbjct: 477  EELRTTVD-SVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEK 535

Query: 970  -----NIENLNMNVEELNKMNLELIDKH----VQKQQTQSPDYTEQYINEINKLNALLKQ 1020
                  IE L  N E   K+ LE  ++H    V   + +S    E  + +I K N +L +
Sbjct: 536  AQLEKTIETLRENSERQIKI-LEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHE 594

Query: 1021 KDEEIIALNQKINNAQVSYMSMVSDYESK---LAQFTTKLENMEEEMQRVSKQLLDSKQH 1077
              +E  +   KI   +      +  Y+ K     +   +L ++E+E + + K++ + K  
Sbjct: 595  SIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKIT 654

Query: 1078 NEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXX 1137
             E+++ L +E  +  +E ++ K T + +       + S   E    D  N++        
Sbjct: 655  CEKIEALEQENSELERENRKLKKTLD-SFKNLTFQLESLEKENSQLDEENLELRRNVESL 713

Query: 1138 XXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQ---- 1193
                +K+ + +    E   L+ +  +L   L+       + E L     G D+ NQ    
Sbjct: 714  KCASMKMAQLQ---LENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQK 770

Query: 1194 ------EQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQRE 1247
                  ++I QL+S+L+ L  EN  L   + EL+ S S  ++Q   E   L +Q  +Q E
Sbjct: 771  TLENSNKKIQQLESELQDLEMENQTLQKNLEELKIS-SKRLEQLEKENKSL-EQETSQLE 828

Query: 1248 ADFQKTEHE---LRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQN--KLQDK 1302
             D ++ E E   LR Q    ++  E+  ++V+    E+ NK ++ E     ++  +L++ 
Sbjct: 829  KDKKQLEKENKRLRQQAEIKDTTLEE--NNVKIGNLEKENKTLSKEIGIYKESCVRLKEL 886

Query: 1303 EEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQM 1362
            E+  + L ++    I  +  LR ++  EK+                  +    N+     
Sbjct: 887  EKENKELVKRATIDIKTLVTLREDLVSEKLK--TQQMNNDLEKLTHELEKIGLNKERLLH 944

Query: 1363 QEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHE 1422
             EQS  +   +  + K  S            ++   EA++ E T+  +    E+      
Sbjct: 945  DEQSTDDSRYKLLESKLESTLKKSLEIKEE-KIAALEARLEESTNYNQQLRQELKTVKKN 1003

Query: 1423 YTITLTQRNDEFENVRQQLVEYEKRI--EDLTYEKESELAILRL-KMHENANHYETMQKE 1479
            Y   L QR DE     +++V+    I  ED  +E+ES+     L K+ +     E     
Sbjct: 1004 YE-ALKQRQDE-----ERMVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVERNNAT 1057

Query: 1480 SEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDE 1539
             + E+  L  +L    T++ +L  Q+  L +       +   +QT     ++E  TLN +
Sbjct: 1058 LQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQ 1117

Query: 1540 ITNLQN 1545
             T+L N
Sbjct: 1118 STSLMN 1123



 Score = 98.3 bits (234), Expect = 2e-18
 Identities = 158/809 (19%), Positives = 336/809 (41%), Gaps = 68/809 (8%)

Query: 749  TQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQE 808
            +Q  I+  ++   L+++ +  E  ++   I  L E    +    ++        GS   +
Sbjct: 182  SQEDIEPLLKNMALHLKRLIDERDEHSETIIELSEERDGLHFLPHASSSAQSPCGSPGMK 241

Query: 809  KQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQIS 868
            + ++    +++  +   ++  L        +QLL+ + E ++++ + + L +EN NL   
Sbjct: 242  RTESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSD 301

Query: 869  LSDMQQH---YNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEI 925
                + +    +AL EKA R D  ESE ++Y+ +L D+E    R         V++ KE 
Sbjct: 302  ARSARMYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKAR---------VEELKED 352

Query: 926  EDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMN 985
              + +E  T +E  +   +  ++K  +  +   QL+A+L + +   +     +EEL + N
Sbjct: 353  NQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEEN 412

Query: 986  LELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSD 1045
            + L  +  QKQ      +    + +I++ + L +   +   +L  ++N    S +  +  
Sbjct: 413  MTL--EMAQKQSMDESLHLGWELEQISRTSELSEAPQK---SLGHEVNELTSSRLLKLEM 467

Query: 1046 YESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMN 1105
                L +   +L    + ++  + ++L  ++ N+ L   V   +++I + K++ L    N
Sbjct: 468  ENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQS-LQNCQN 526

Query: 1106 IPK---TEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSA 1162
            + K    E   +  TIE + +++                +  QE E   Q  S L+++S 
Sbjct: 527  LSKDLMKEKAQLEKTIETLRENSER-----------QIKILEQENEHLNQTVSSLRQRS- 574

Query: 1163 KLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRS 1222
            +++ E      ++  +E  N  L        E I +  SKL ++  E   +   +   + 
Sbjct: 575  QISAE-----ARVKDIEKENKIL-------HESIKETSSKLSKIEFEKRQIKKELEHYKE 622

Query: 1223 SISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEE 1282
                   +R  E+ E    HL +     QK    L++     E+     L+   S  + E
Sbjct: 623  K-----GERAEEL-ENELHHLEKENELLQKKITNLKITCEKIEA-----LEQENSELERE 671

Query: 1283 TNKI-VTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILR-SEIEDEKVAFXXXXXX 1340
              K+  T++   +L  +L+  E+    L E+  ++   +E L+ + ++  ++        
Sbjct: 672  NRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELE 731

Query: 1341 XXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEA 1400
                      +L   +    +  E S   ++ EN +L+K+              + D E 
Sbjct: 732  SEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEM 791

Query: 1401 KVLELTHQL-ELK-DSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESE 1458
            +   L   L ELK  S+  ++  +   +L Q   + E  ++QL +  KR+      K++ 
Sbjct: 792  ENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTT 851

Query: 1459 LAILRLKMHENANHYETMQKESEI-----ERVKLIEELNVKITESVSLN-KQVAELNKAL 1512
            L    +K+       +T+ KE  I      R+K +E+ N ++ +  +++ K +  L + L
Sbjct: 852  LEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDL 911

Query: 1513 EEEVAKTNEMQTALE--NQEIEIVTLNDE 1539
              E  KT +M   LE    E+E + LN E
Sbjct: 912  VSEKLKTQQMNNDLEKLTHELEKIGLNKE 940



 Score = 93.5 bits (222), Expect = 4e-17
 Identities = 178/885 (20%), Positives = 369/885 (41%), Gaps = 72/885 (8%)

Query: 213  DTKQQMTKMQENFIAMEAEWKDEKQRLLKDIE--SKDVRISSLEEANKLLEAARFEISLE 270
            +T ++ ++ Q   +  E E  ++    L+     S + R+  +E+ NK+L  +  E S +
Sbjct: 543  ETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSK 602

Query: 271  HSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIEL 330
             SK+  E E+                 + +E       +  E    +I N+    +KIE 
Sbjct: 603  LSKI--EFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEA 660

Query: 331  LEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRK-SGRNTASKMKSPWSQL 389
            LE  N ++ + N++L+  L +    +  + S  K+ S L       R     +K    ++
Sbjct: 661  LEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKM 720

Query: 390  SSETLNQDTDKKINKNEIAK-LEMVIQSLNK-DLVDKEYVISEKDTXXXXXXXXXXGKDT 447
            +   L ++ + +  K ++ K LE++  S  K + ++  Y     D             + 
Sbjct: 721  AQLQL-ENKELESEKEQLKKGLELLKASFKKTERLEVSY--QGLDIENQRLQKTLENSNK 777

Query: 448  LIAQLQLEHQQ-HMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLK 506
             I QL+ E Q   ME  +L     N E++   +K  EQL++E                 K
Sbjct: 778  KIQQLESELQDLEMENQTL---QKNLEELKISSKRLEQLEKE----------------NK 818

Query: 507  SAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHH 566
            S E++ +QL  +     K   +++   ++K   ++   +N  K+ +  KE   L++E+  
Sbjct: 819  SLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLE---ENNVKIGNLEKENKTLSKEIGI 875

Query: 567  LSQKVAELEE-EKGNLQL---HLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQ 622
              +    L+E EK N +L     +D  +   +  D+  + ++ + +     K    LE  
Sbjct: 876  YKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKI 935

Query: 623  KFDLVQELHILQQKYDEVEDKLADISQLQSDQVCS-EIKSVHLEEQIDALSASKKELALV 681
              +  + LH  +Q  D+   KL + S+L+S    S EIK    EE+I AL A  +E    
Sbjct: 936  GLNKERLLHD-EQSTDDSRYKLLE-SKLESTLKKSLEIK----EEKIAALEARLEESTNY 989

Query: 682  IENLKLDKEQL---YGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAK 738
             + L+ + + +   Y  +K  ++++  + +      ++N     K E+ S E   ELL K
Sbjct: 990  NQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGEDN-----KWERESQETTRELL-K 1043

Query: 739  INHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERK 798
            +        +    + A+ Q     ++ +E++ +  +++I  L+     ++++  +L+ +
Sbjct: 1044 VKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQ 1103

Query: 799  ADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQIL 858
              +L       Q   S    Q   L+N+ A L+     +E +   +  E ++L+     L
Sbjct: 1104 NAKL-------QVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSL 1156

Query: 859  LEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLI 918
            +++++ L++        Y +L+ K      A          L D  + L +   + + L 
Sbjct: 1157 IKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKGQLEDLE 1216

Query: 919  VQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQ--LQEYKNNIENLNM 976
               K E E + +E       A   KK+  E    N  Y   L+    LQ    N+++L +
Sbjct: 1217 KMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLLKETEVLQTDHKNLKSL-L 1275

Query: 977  NVEELNKMNLELIDKHVQKQQTQSPDYTEQYINE----INKLNALLKQKDEEIIALNQ-- 1030
            N  +L +  LE  +    K+Q Q  D T   +N     +++L   L++++  ++   Q  
Sbjct: 1276 NNSKLEQTRLE-AEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLEEENRHLLDQIQTL 1334

Query: 1031 KINNAQVSYMSMVSD--YESKLAQFTTKLENMEEEMQRVSKQLLD 1073
             + N  +   +M S   +  +  Q+  KL  +  + +++ ++++D
Sbjct: 1335 MLQNRTLLEQNMESKDLFHVEQRQYIDKLNELRRQKEKLEEKIMD 1379


>UniRef50_Q4N897 Cluster: Putative uncharacterized protein; n=2;
            Theileria|Rep: Putative uncharacterized protein -
            Theileria parva
          Length = 1723

 Score =  134 bits (324), Expect = 2e-29
 Identities = 254/1266 (20%), Positives = 525/1266 (41%), Gaps = 103/1266 (8%)

Query: 213  DTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHS 272
            D  + + +  + F     E++ +KQ L       D   S+LE   + LE  +     +  
Sbjct: 225  DRNKDLNRKIKEFNQKNDEFEKQKQALDDQKSKYDSLNSNLEVRTRDLEREKDNYKRKTD 284

Query: 273  KLAQ---ELEQ--XXXXXXXXXXXXXXLAKQSIEPSCEEKTE-IEEKGSLEIANMTELTK 326
            KLA+   EL++                LA Q  E    +++E +E + +  +    +L +
Sbjct: 285  KLAEMELELQEDIKFYHKKQDELNAERLALQDKEKDYAKRSEDLESERTKILDKDRKLEE 344

Query: 327  KIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPW 386
            ++  ++     + Q +++ +  L T   E+  V   + KG  L S +S R + +  +   
Sbjct: 345  ELARIKEKEATLTQQHQKKDENL-TQREEALKVELETNKGL-LASIESQRTSLASEQREL 402

Query: 387  SQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKD 446
                 E    + +       + KL+   ++  + +V+    +SE+ T           KD
Sbjct: 403  ESKKQEQKLLEANINTETQRLEKLKQENEAAKEHMVNYGKFLSEETTKLNKIK-----KD 457

Query: 447  TLIAQLQL-EHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKL 505
               A+  L E +Q ++  S        E+  E  ++Q+ L+ +++ E K  N K L E+L
Sbjct: 458  NEAAKAVLDEREQKLDEESQKIDQLKVENSKEAKRLQD-LQADIDKE-KLANTK-LSEQL 514

Query: 506  KSAEEQITQLNDEIDAANKNMIKVKSNHKLKL-KQMQKTI-DNFSKVSDSNKEIVRLTEE 563
                +++     E +   K+  + K+   L+  K +QK I +N +  +   K+   +  E
Sbjct: 515  NRERDELATKTQEQERL-KSEYESKNTQILETEKNLQKQISENETLAATLKKQEKDIEAE 573

Query: 564  LHHLSQKVAELEEEKGNLQLHLVDYDSGRMI--ESDVYKKMIEMENLAETRLKAISLLES 621
               + +++  L +E+ N Q +++ Y + +     S +  K   +E+      +  + L+S
Sbjct: 574  NEKIKKEIERLNQEERN-QAYILKYTAKQQSRKSSALLNKQKNLEDQIRLNTEKAASLQS 632

Query: 622  QKFDLVQELHILQQKYDEVEDKLADISQLQSDQV--CSEIKSVHLEEQIDALSASKKELA 679
            Q+ +L ++   +Q +  ++E +  ++ Q +       + ++    + Q  AL   K+E  
Sbjct: 633  QQQNLTEQTQRVQAELSDLERQRGEVQQKEEKLKLDTASVEEAKKKNQQRALDLKKQENT 692

Query: 680  L-VIEN-LKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLT---DKLEKMSAEKISE 734
            +   EN L + + Q     K L+ D++ +  KL  + ++    T   ++ +K   EK  E
Sbjct: 693  VQERENKLLIAQAQNISKAKQLKKDQDVLNTKLAEHTEDVRRKTLEFEQRDKTLKEKELE 752

Query: 735  L---LAKINHEEQSKIQTQFGI-DAKIQERDLYIENIESELSKYKSRICRLEESIAVMED 790
                LA++  + ++  + Q  + DA+ Q R   + ++E E    K+R  +  E +A ++ 
Sbjct: 753  YQLKLAEVAEDHKTLFREQSLLNDAREQLRRDELAHMEKEKEAEKARQAKETELLATIK- 811

Query: 791  RRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKE 850
                 +++ + L    +EKQK  +E   QE +L  R      HD  + +   E++ +  +
Sbjct: 812  -----QQETESLARIAEEKQKREAEILAQEQQLQQRRQA---HDDQIRRSQEELDRKIAD 863

Query: 851  LQKKNQILLEENQNLQISLSDMQQHYNALVEKANRT------DLAESESTKYQTQLRDLE 904
             ++K+    E   N Q  +  ++    A   +A R          E E  K Q Q ++L 
Sbjct: 864  DKQKSAEAEERINNRQKEVDALKSDLEAKNAEAERLLSGHLHTKGELEKLKAQLQQQNLA 923

Query: 905  S-NLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQ 963
            +  L +   E    + Q+         E N  +ES       L+ +        ++LEA 
Sbjct: 924  AQKLTKTLEEQNEAVKQENARATAANQEANRLLESNRAQAASLSRR-------ESELEAN 976

Query: 964  LQEYKNNIENLNMNVEELNKMNLELIDKHVQ-KQQTQSPDYTEQYINEINKLNALLKQKD 1022
            +  Y   ++++      L  +N  L+ K      + Q+    E+ ++E  +   L KQK 
Sbjct: 977  MDAYTIKLKSVQDEDARLTALNKTLLLKEESLGTRDQNVKDKERRVSE-REAEVLKKQKQ 1035

Query: 1023 EEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQ 1082
            +E      K  + Q    S++   E+ L Q  ++    ++E   +S++L D +    EL 
Sbjct: 1036 QE------KTESEQNQRQSLLQSRENTLNQKESQQRTKDQEQSELSQKLADKQ---AELT 1086

Query: 1083 ILVREQDDQIKEL--KETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXX 1140
             L  + D   K+L  ++ +LT   N  +        T +   + AN +            
Sbjct: 1087 ALQSKLDQLQKDLDARQLQLTEAENAVRLRETKADETEKAQKNKANELLLEDEKVKRLGR 1146

Query: 1141 XLKVQEEEEFIQER------SVLQEQSAKL----NTELQECYT----KIIQLETLNTELT 1186
             ++ + +   IQE       S L E+ AK+      +L+E  T    +  +++ ++T+L 
Sbjct: 1147 EVEAKRQLAIIQENKNTQRSSELDEKQAKVEKLATDKLRELETIRTQQAEEIKNVSTQLK 1206

Query: 1187 GHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQR 1246
              +   ++ I +L +K E+L  +N ++LS    + SS  S +         + K  L++ 
Sbjct: 1207 NKETELEQTIAKLNAKYEELKLDNKSVLSANRVMLSSAESNL--------IITKSELSRT 1258

Query: 1247 EADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHL 1306
            ++D    + EL  + S  E++ ++       + + ET       Q+T   N+L       
Sbjct: 1259 KSDLNTVKLELSTRTSELEAEKQKNSTLEAKNNELETQLSTAKSQLTEKGNELSQCVVRE 1318

Query: 1307 RNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQS 1366
              L+ + +D+ +Q+++ +S+  DEK                    LR +  +  Q +   
Sbjct: 1319 TTLKSEKSDLESQLKV-KSDRYDEK---EKEYDTLKNLHKEAQSKLREKESAVSQCE--- 1371

Query: 1367 ILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTH---QLELKDSEIYQKTHEY 1423
             + ++E+N QL+  +            + ++ E KVLEL     +LE K  E+  +    
Sbjct: 1372 -VKLSEKNTQLESVTEQLGGKQKSLEQKTSELEGKVLELADKNLELERKQKEVLDRDARL 1430

Query: 1424 TITLTQ 1429
             I  TQ
Sbjct: 1431 LIKETQ 1436



 Score =  132 bits (319), Expect = 8e-29
 Identities = 233/1151 (20%), Positives = 473/1151 (41%), Gaps = 101/1151 (8%)

Query: 503  EKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTE 562
            E LK   E+   LN E+   N+    + + +      MQK    ++K  D NK++ R  +
Sbjct: 186  EILKERLEKYVNLNRELHKKNEEAENLYNAY------MQK----YAKFYDRNKDLNRKIK 235

Query: 563  ELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQ 622
            E +   QK  E E++K  L      YDS   + S++  +  ++E   +   +    L   
Sbjct: 236  EFN---QKNDEFEKQKQALDDQKSKYDS---LNSNLEVRTRDLEREKDNYKRKTDKLAEM 289

Query: 623  KFDLVQELHILQQKYDEV-------EDKLADISQLQSDQVCSEIKSVHLEEQIDALSA-- 673
            + +L +++    +K DE+       +DK  D ++   D      K +  + +++   A  
Sbjct: 290  ELELQEDIKFYHKKQDELNAERLALQDKEKDYAKRSEDLESERTKILDKDRKLEEELARI 349

Query: 674  SKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKIS 733
             +KE  L  ++ K D E L    + L+ + E     L +   +   L  +  ++ ++K  
Sbjct: 350  KEKEATLTQQHQKKD-ENLTQREEALKVELETNKGLLASIESQRTSLASEQRELESKKQE 408

Query: 734  ELL--AKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDR 791
            + L  A IN E Q   + +   +A  +    Y + +  E +K        E + AV+++R
Sbjct: 409  QKLLEANINTETQRLEKLKQENEAAKEHMVNYGKFLSEETTKLNKIKKDNEAAKAVLDER 468

Query: 792  RYSLE---RKADQLGSYLQEKQKAYSEYT--IQEDELVN-RLAVLMDHDR-VVEKQLLEI 844
               L+   +K DQL     ++ K   +    I +++L N +L+  ++ +R  +  +  E 
Sbjct: 469  EQKLDEESQKIDQLKVENSKEAKRLQDLQADIDKEKLANTKLSEQLNRERDELATKTQEQ 528

Query: 845  EHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQ-LRDL 903
            E    E + KN  +LE  +NLQ  +S+  +   A ++K  +   AE+E  K + + L   
Sbjct: 529  ERLKSEYESKNTQILETEKNLQKQISE-NETLAATLKKQEKDIEAENEKIKKEIERLNQE 587

Query: 904  ESN---LKRITHEHQT----LIVQKKKEIEDLEIEFNTQIESAIRDKKV-LNEKYEKNIE 955
            E N   + + T + Q+     ++ K+K +ED +I  NT+  ++++ ++  L E+ ++   
Sbjct: 588  ERNQAYILKYTAKQQSRKSSALLNKQKNLED-QIRLNTEKAASLQSQQQNLTEQTQRVQA 646

Query: 956  YVTQLEAQLQEYKNNIENLNMN---VEELNKMNLE-LIDKHVQKQQTQSPDYTEQYINEI 1011
             ++ LE Q  E +   E L ++   VEE  K N +  +D   Q+   Q  +         
Sbjct: 647  ELSDLERQRGEVQQKEEKLKLDTASVEEAKKKNQQRALDLKKQENTVQERENKLLIAQAQ 706

Query: 1012 NKLNALLKQKDEEIIALN-----QKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQR 1066
            N   A   +KD++++        + +    + +       + K  ++  KL  + E+ + 
Sbjct: 707  NISKAKQLKKDQDVLNTKLAEHTEDVRRKTLEFEQRDKTLKEKELEYQLKLAEVAEDHKT 766

Query: 1067 VSKQ---LLDSKQH--NEELQILVREQD-DQIKELKETKLTFEMNIPKTEGMI-ISSTIE 1119
            + ++   L D+++    +EL  + +E++ ++ ++ KET+L   +   +TE +  I+   +
Sbjct: 767  LFREQSLLNDAREQLRRDELAHMEKEKEAEKARQAKETELLATIKQQETESLARIAEEKQ 826

Query: 1120 PMSDD--ANNVDXXXXXXXXXXXXLKVQEE--EEFIQERSVLQEQSAKLNTELQECYTKI 1175
                +  A                 + QEE   +   ++    E   ++N   +E     
Sbjct: 827  KREAEILAQEQQLQQRRQAHDDQIRRSQEELDRKIADDKQKSAEAEERINNRQKEVDALK 886

Query: 1176 IQLETLNTE----LTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSI---SSAV 1228
              LE  N E    L+GH +  + ++ +LK++L+Q N     L  T+ E   ++   ++  
Sbjct: 887  SDLEAKNAEAERLLSGH-LHTKGELEKLKAQLQQQNLAAQKLTKTLEEQNEAVKQENARA 945

Query: 1229 DQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVT 1288
                 E   L + + AQ  A   + E EL   + A+  K + + D     T      ++ 
Sbjct: 946  TAANQEANRLLESNRAQA-ASLSRRESELEANMDAYTIKLKSVQDEDARLTALNKTLLLK 1004

Query: 1289 MEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXX 1348
             E + +    ++DKE   R + E+ A+V+ + +  + + E E+                 
Sbjct: 1005 EESLGTRDQNVKDKE---RRVSEREAEVLKK-QKQQEKTESEQNQRQSLLQSRENTLNQK 1060

Query: 1349 XXDLRTENQSYKQMQEQ------SILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKV 1402
                RT++Q   ++ ++       +  +  +  QL+K               V   E K 
Sbjct: 1061 ESQQRTKDQEQSELSQKLADKQAELTALQSKLDQLQKDLDARQLQLTEAENAVRLRETKA 1120

Query: 1403 LEL-------THQLELKDSEIYQKTHEYT----ITLTQRNDEFENVRQQLVEYEKRIEDL 1451
             E         ++L L+D ++ +   E      + + Q N   +    +L E + ++E L
Sbjct: 1121 DETEKAQKNKANELLLEDEKVKRLGREVEAKRQLAIIQENKNTQR-SSELDEKQAKVEKL 1179

Query: 1452 TYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKA 1511
              +K  EL  +R +  E   +  T  K  E E  + I +LN K  E    NK V   N+ 
Sbjct: 1180 ATDKLRELETIRTQQAEEIKNVSTQLKNKETELEQTIAKLNAKYEELKLDNKSVLSANRV 1239

Query: 1512 LEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQ 1571
            +      + E    +   E+     +     L+   R S  + +K  +   + K    E 
Sbjct: 1240 M----LSSAESNLIITKSELSRTKSDLNTVKLELSTRTSELEAEKQKNSTLEAKNNELET 1295

Query: 1572 LDNTMNKELLD 1582
              +T   +L +
Sbjct: 1296 QLSTAKSQLTE 1306



 Score =  124 bits (300), Expect = 2e-26
 Identities = 224/1182 (18%), Positives = 490/1182 (41%), Gaps = 126/1182 (10%)

Query: 475  VNEIAKVQEQLKQELNDEIKDVNVK-DLIEKLKSA----EEQITQLNDEIDAANKNMIKV 529
            + + AK  ++ K +LN +IK+ N K D  EK K A    + +   LN  ++   +++ + 
Sbjct: 217  MQKYAKFYDRNK-DLNRKIKEFNQKNDEFEKQKQALDDQKSKYDSLNSNLEVRTRDLERE 275

Query: 530  KSNHKLKLK-------QMQKTIDNFSKVSDS-NKEIVRLTEELHHLSQKVAELEEEKGNL 581
            K N+K K         ++Q+ I  + K  D  N E + L ++    +++  +LE E+  +
Sbjct: 276  KDNYKRKTDKLAEMELELQEDIKFYHKKQDELNAERLALQDKEKDYAKRSEDLESERTKI 335

Query: 582  --QLHLVDYDSGRMIESDV---YKKMIEMENLA----------ETRLKAISLLESQKFDL 626
              +   ++ +  R+ E +     +   + ENL           ET    ++ +ESQ+  L
Sbjct: 336  LDKDRKLEEELARIKEKEATLTQQHQKKDENLTQREEALKVELETNKGLLASIESQRTSL 395

Query: 627  VQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASK--KELALVIEN 684
              E   L+ K  + E KL + +     Q   ++K  +   +   ++  K   E    +  
Sbjct: 396  ASEQRELESK--KQEQKLLEANINTETQRLEKLKQENEAAKEHMVNYGKFLSEETTKLNK 453

Query: 685  LKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKL---------EKMSAEKISEL 735
            +K D E     + + E   ++   K+     EN     +L         EK++  K+SE 
Sbjct: 454  IKKDNEAAKAVLDEREQKLDEESQKIDQLKVENSKEAKRLQDLQADIDKEKLANTKLSEQ 513

Query: 736  LAKINHEEQSKIQTQFGIDAKIQERDLYI----ENIESELSKYKSRICRLEESIAVMEDR 791
            L +   E  +K Q Q  + ++ + ++  I    +N++ ++S+ ++    L++    +E  
Sbjct: 514  LNRERDELATKTQEQERLKSEYESKNTQILETEKNLQKQISENETLAATLKKQEKDIEAE 573

Query: 792  RYSLERKADQLGSYLQEKQKAYS-EYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKE 850
               ++++ ++L    +E+ +AY  +YT ++     + + L++  + +E Q+     +   
Sbjct: 574  NEKIKKEIERLNQ--EERNQAYILKYTAKQQS--RKSSALLNKQKNLEDQIRLNTEKAAS 629

Query: 851  LQKKNQILLEENQNLQISLSDMQQHYNALVEKANRT--DLAESESTKYQTQLRDLESNLK 908
            LQ + Q L E+ Q +Q  LSD+++    + +K  +   D A  E  K + Q R L+   +
Sbjct: 630  LQSQQQNLTEQTQRVQAELSDLERQRGEVQQKEEKLKLDTASVEEAKKKNQQRALDLKKQ 689

Query: 909  RIT---HEHQTLIVQ-----KKKEIEDLEIEFNTQIESAIRD--KKVLNEKY------EK 952
              T    E++ LI Q     K K+++  +   NT++     D  +K L  +       EK
Sbjct: 690  ENTVQERENKLLIAQAQNISKAKQLKKDQDVLNTKLAEHTEDVRRKTLEFEQRDKTLKEK 749

Query: 953  NIEYVTQLEAQLQEYKNNIEN---LNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYIN 1009
             +EY  +L    +++K        LN   E+L +  L  ++K  + ++ +    TE    
Sbjct: 750  ELEYQLKLAEVAEDHKTLFREQSLLNDAREQLRRDELAHMEKEKEAEKARQAKETE---- 805

Query: 1010 EINKLNALLKQKDEEIIA-LNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVS 1068
                L A +KQ++ E +A + ++    +   ++     + +      ++   +EE+ R  
Sbjct: 806  ----LLATIKQQETESLARIAEEKQKREAEILAQEQQLQQRRQAHDDQIRRSQEELDR-- 859

Query: 1069 KQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNV 1128
             ++ D KQ + E +  +  +  ++  LK      E    + E ++          +    
Sbjct: 860  -KIADDKQKSAEAEERINNRQKEVDALKSD---LEAKNAEAERLLSGHLHTKGELEKLKA 915

Query: 1129 DXXXXXXXXXXXXLKVQEEEEFI-QERSVLQEQSAKLNTELQECYTKIIQLETLNTELTG 1187
                           ++E+ E + QE +     + + N  L+    +   L    +EL  
Sbjct: 916  QLQQQNLAAQKLTKTLEEQNEAVKQENARATAANQEANRLLESNRAQAASLSRRESELEA 975

Query: 1188 HDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQRE 1247
            +      ++  ++ +  +L   N  LL     L +   +  D+         ++ +++RE
Sbjct: 976  NMDAYTIKLKSVQDEDARLTALNKTLLLKEESLGTRDQNVKDK---------ERRVSERE 1026

Query: 1248 ADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTS-LQNKLQDKEEHL 1306
            A+  K + + + +  + +++ + LL S +++  ++ ++  T +Q  S L  KL DK+  L
Sbjct: 1027 AEVLKKQKQ-QEKTESEQNQRQSLLQSRENTLNQKESQQRTKDQEQSELSQKLADKQAEL 1085

Query: 1307 RNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQS 1366
              LQ K   +   ++  + ++ + + A                   +    +   ++++ 
Sbjct: 1086 TALQSKLDQLQKDLDARQLQLTEAENAVRLRETKADETEKA-----QKNKANELLLEDEK 1140

Query: 1367 ILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTIT 1426
            +  +  E    ++ +             +++ +AKV +L             K  E    
Sbjct: 1141 VKRLGREVEAKRQLAIIQENKNTQRSSELDEKQAKVEKLATD----------KLRELETI 1190

Query: 1427 LTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRL--KMHENANHYETMQKESEI-- 1482
             TQ+ +E +NV  QL   E  +E    +  ++   L+L  K   +AN       ES +  
Sbjct: 1191 RTQQAEEIKNVSTQLKNKETELEQTIAKLNAKYEELKLDNKSVLSANRVMLSSAESNLII 1250

Query: 1483 ---ERVKLIEELN-VKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLND 1538
               E  +   +LN VK+  S   ++  AE  K    E AK NE++T L   + ++    +
Sbjct: 1251 TKSELSRTKSDLNTVKLELSTRTSELEAEKQKNSTLE-AKNNELETQLSTAKSQLTEKGN 1309

Query: 1539 EITNL---QNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMN 1577
            E++     +  +++  S ++  +   SD    ++++ D   N
Sbjct: 1310 ELSQCVVRETTLKSEKSDLESQLKVKSDRYDEKEKEYDTLKN 1351



 Score =  113 bits (273), Expect = 3e-23
 Identities = 207/1129 (18%), Positives = 476/1129 (42%), Gaps = 83/1129 (7%)

Query: 477  EIAKVQEQLKQELNDEI-KDVNVKDLIEKLKSAEEQITQLNDEID---AANKNMIKVK-- 530
            + AK  E L+ E    + KD  +++ + ++K  E  +TQ + + D      +  +KV+  
Sbjct: 320  DYAKRSEDLESERTKILDKDRKLEEELARIKEKEATLTQQHQKKDENLTQREEALKVELE 379

Query: 531  SNHKL--KLKQMQKTIDNFSKVSDSNKEIVRLTE-ELHHLSQKVAELEEEKGNLQLHLVD 587
            +N  L   ++  + ++ +  +  +S K+  +L E  ++  +Q++ +L++E    + H+V+
Sbjct: 380  TNKGLLASIESQRTSLASEQRELESKKQEQKLLEANINTETQRLEKLKQENEAAKEHMVN 439

Query: 588  YDSGRMIESDVYK-KMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLAD 646
            Y  G+ +  +  K   I+ +N A    KA+     QK D  +E   + Q   E   +   
Sbjct: 440  Y--GKFLSEETTKLNKIKKDNEAA---KAVLDEREQKLD--EESQKIDQLKVENSKEAKR 492

Query: 647  ISQLQSDQVCSEIKSVHLEEQI----DALSASKKELALVIENLKLDKEQLYGTIKDLE-- 700
            +  LQ+D    ++ +  L EQ+    D L+   +E   +    +    Q+  T K+L+  
Sbjct: 493  LQDLQADIDKEKLANTKLSEQLNRERDELATKTQEQERLKSEYESKNTQILETEKNLQKQ 552

Query: 701  -NDKEDI---MNKLQNYIQ-ENMDLTDKLEKMSAEKISEL-LAKINHEEQSK-----IQT 749
             ++ E +   + K +  I+ EN  +  ++E+++ E+ ++  + K   ++QS+     +  
Sbjct: 553  ISENETLAATLKKQEKDIEAENEKIKKEIERLNQEERNQAYILKYTAKQQSRKSSALLNK 612

Query: 750  QFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLG---SYL 806
            Q  ++ +I+       +++S+      +  R++  ++ +E +R  +++K ++L    + +
Sbjct: 613  QKNLEDQIRLNTEKAASLQSQQQNLTEQTQRVQAELSDLERQRGEVQQKEEKLKLDTASV 672

Query: 807  QEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQ-LLEIEHENKELQKKNQILLEENQNL 865
            +E +K   +  +   +  N +    +   + + Q + + +   K+    N  L E  +++
Sbjct: 673  EEAKKKNQQRALDLKKQENTVQERENKLLIAQAQNISKAKQLKKDQDVLNTKLAEHTEDV 732

Query: 866  QISLSDMQQHYNALVEKA-----NRTDLAESESTKYQTQ--LRDLESNLKRITHEHQTLI 918
            +    + +Q    L EK         ++AE   T ++ Q  L D    L+R    H    
Sbjct: 733  RRKTLEFEQRDKTLKEKELEYQLKLAEVAEDHKTLFREQSLLNDAREQLRRDELAH---- 788

Query: 919  VQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNV 978
            ++K+KE E       T++ + I+ ++   E   +  E   + EA++   +  ++      
Sbjct: 789  MEKEKEAEKARQAKETELLATIKQQET--ESLARIAEEKQKREAEILAQEQQLQQRRQAH 846

Query: 979  EELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNAL-----LKQKDEEIIALNQKIN 1033
            ++  + + E +D+ +   + +S +  E+  N   +++AL      K  + E +       
Sbjct: 847  DDQIRRSQEELDRKIADDKQKSAEAEERINNRQKEVDALKSDLEAKNAEAERLLSGHLHT 906

Query: 1034 NAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIK 1093
              ++  +      ++  AQ  TK   +EE+ + V ++   +   N+E   L+     Q  
Sbjct: 907  KGELEKLKAQLQQQNLAAQKLTK--TLEEQNEAVKQENARATAANQEANRLLESNRAQAA 964

Query: 1094 ELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQE 1153
             L   +   E N+      + S   E     A N                V+++E  + E
Sbjct: 965  SLSRRESELEANMDAYTIKLKSVQDEDARLTALNKTLLLKEESLGTRDQNVKDKERRVSE 1024

Query: 1154 RS--VLQEQSAKLNTELQECYTKII---QLETLNTELTGHDVVNQEQINQLKSKLEQLNT 1208
            R   VL++Q  +  TE ++   + +   +  TLN + +     +QEQ ++L  KL     
Sbjct: 1025 REAEVLKKQKQQEKTESEQNQRQSLLQSRENTLNQKESQQRTKDQEQ-SELSQKLADKQA 1083

Query: 1209 ENDNLLSTVAELRSSISSAVDQRGFEIAELWKQ-HLAQREAD-FQKTEHELRVQLSAFES 1266
            E   L S + +L+  +    D R  ++ E      L + +AD  +K +     +L   + 
Sbjct: 1084 ELTALQSKLDQLQKDL----DARQLQLTEAENAVRLRETKADETEKAQKNKANELLLEDE 1139

Query: 1267 KYEQLLDSVQSSTQ----EETNKIVTMEQVTSLQNKLQD-KEEHLRNLQEKYADVINQIE 1321
            K ++L   V++  Q    +E        ++   Q K++    + LR L+        +I+
Sbjct: 1140 KVKRLGREVEAKRQLAIIQENKNTQRSSELDEKQAKVEKLATDKLRELETIRTQQAEEIK 1199

Query: 1322 ILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSS 1381
             + +++++++                   D ++   + + M   +  N+    ++L ++ 
Sbjct: 1200 NVSTQLKNKETELEQTIAKLNAKYEELKLDNKSVLSANRVMLSSAESNLIITKSELSRTK 1259

Query: 1382 XXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQL 1441
                        R ++ EA+  +    LE K++E+  +       LT++ +E      Q 
Sbjct: 1260 SDLNTVKLELSTRTSELEAEK-QKNSTLEAKNNELETQLSTAKSQLTEKGNELS----QC 1314

Query: 1442 VEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSL 1501
            V  E  ++    + ES+L +   +  E    Y+T++   +  + KL E+ +      V L
Sbjct: 1315 VVRETTLKSEKSDLESQLKVKSDRYDEKEKEYDTLKNLHKEAQSKLREKESAVSQCEVKL 1374

Query: 1502 NKQVAELNKALEEEVAKTNEMQ---TALENQEIEIVTLNDEITNLQNMV 1547
            +++  +L    E+   K   ++   + LE + +E+   N E+   Q  V
Sbjct: 1375 SEKNTQLESVTEQLGGKQKSLEQKTSELEGKVLELADKNLELERKQKEV 1423



 Score = 91.1 bits (216), Expect = 2e-16
 Identities = 175/946 (18%), Positives = 384/946 (40%), Gaps = 100/946 (10%)

Query: 700  ENDKEDIMNKLQNYIQENMDLTDKLEKMSA--EKISELLAKINHEEQSKIQTQFGIDAKI 757
            + ++E +  +L+ Y+  N +L  K E+         +  AK     +   +     + K 
Sbjct: 182  KTEQEILKERLEKYVNLNRELHKKNEEAENLYNAYMQKYAKFYDRNKDLNRKIKEFNQKN 241

Query: 758  QERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYT 817
             E +   + ++ + SKY S    LE     +E  + + +RK D+L     E Q+    Y 
Sbjct: 242  DEFEKQKQALDDQKSKYDSLNSNLEVRTRDLEREKDNYKRKTDKLAEMELELQEDIKFYH 301

Query: 818  IQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDM-QQHY 876
             ++DEL      L D ++   K+  ++E E  ++  K++ L EE   ++   + + QQH 
Sbjct: 302  KKQDELNAERLALQDKEKDYAKRSEDLESERTKILDKDRKLEEELARIKEKEATLTQQHQ 361

Query: 877  NALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQ- 935
                    R +  + E    +  L  +ES    +  E + L   KK+E + LE   NT+ 
Sbjct: 362  KKDENLTQREEALKVELETNKGLLASIESQRTSLASEQREL-ESKKQEQKLLEANINTET 420

Query: 936  --IESAIRDKKVLNE---KYEKNI-EYVTQL----------EAQLQEYKNNIENLNMNVE 979
              +E   ++ +   E    Y K + E  T+L          +A L E +  ++  +  ++
Sbjct: 421  QRLEKLKQENEAAKEHMVNYGKFLSEETTKLNKIKKDNEAAKAVLDEREQKLDEESQKID 480

Query: 980  ELNKMN------LELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKD---EEIIALNQ 1030
            +L   N      L+ +   + K++  +   +EQ   E ++L    ++++    E  + N 
Sbjct: 481  QLKVENSKEAKRLQDLQADIDKEKLANTKLSEQLNRERDELATKTQEQERLKSEYESKNT 540

Query: 1031 KINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQL--LDSKQHNEE--LQILVR 1086
            +I   + +    +S+ E+  A    + +++E E +++ K++  L+ ++ N+   L+   +
Sbjct: 541  QILETEKNLQKQISENETLAATLKKQEKDIEAENEKIKKEIERLNQEERNQAYILKYTAK 600

Query: 1087 EQDDQIKEL--KETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKV 1144
            +Q  +   L  K+  L  ++ +   +   + S  + +++    V             ++ 
Sbjct: 601  QQSRKSSALLNKQKNLEDQIRLNTEKAASLQSQQQNLTEQTQRVQAELSDLERQRGEVQQ 660

Query: 1145 QEEE--------------------EFIQERSVLQEQSAKLNTELQECYTKIIQL----ET 1180
            +EE+                    +  ++ + +QE+  KL     +  +K  QL    + 
Sbjct: 661  KEEKLKLDTASVEEAKKKNQQRALDLKKQENTVQERENKLLIAQAQNISKAKQLKKDQDV 720

Query: 1181 LNTELTGH--DVVNQE-QINQLKSKLEQLNTENDNLLSTVAE-------LRSSISSAVDQ 1230
            LNT+L  H  DV  +  +  Q    L++   E    L+ VAE        +S ++ A +Q
Sbjct: 721  LNTKLAEHTEDVRRKTLEFEQRDKTLKEKELEYQLKLAEVAEDHKTLFREQSLLNDAREQ 780

Query: 1231 -RGFEIAELWKQHLAQ-----READF------QKTEHELRVQLSAFESKYEQLLDSVQSS 1278
             R  E+A + K+  A+     +E +       Q+TE   R+     + + E L    Q  
Sbjct: 781  LRRDELAHMEKEKEAEKARQAKETELLATIKQQETESLARIAEEKQKREAEILAQEQQLQ 840

Query: 1279 TQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXX 1338
             + + +          L  K+ D ++     +E+  +   +++ L+S++E  K A     
Sbjct: 841  QRRQAHDDQIRRSQEELDRKIADDKQKSAEAEERINNRQKEVDALKSDLE-AKNAEAERL 899

Query: 1339 XXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDA 1398
                         L+ + Q      ++    + E+N  +K+ +             +   
Sbjct: 900  LSGHLHTKGELEKLKAQLQQQNLAAQKLTKTLEEQNEAVKQENARATAANQEANRLLESN 959

Query: 1399 EAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENV----------RQQLVEYEKRI 1448
             A+   L+     ++SE+      YTI L    DE   +           + L   ++ +
Sbjct: 960  RAQAASLSR----RESELEANMDAYTIKLKSVQDEDARLTALNKTLLLKEESLGTRDQNV 1015

Query: 1449 EDLTYE-KESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAE 1507
            +D      E E  +L+ +  +     E  Q++S ++  +    LN K ++  + +++ +E
Sbjct: 1016 KDKERRVSEREAEVLKKQKQQEKTESEQNQRQSLLQSRE--NTLNQKESQQRTKDQEQSE 1073

Query: 1508 LNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSK 1553
            L++ L ++ A+   +Q+ L+  + ++     ++T  +N VR   +K
Sbjct: 1074 LSQKLADKQAELTALQSKLDQLQKDLDARQLQLTEAENAVRLRETK 1119


>UniRef50_A2ESN0 Cluster: Viral A-type inclusion protein, putative;
            n=1; Trichomonas vaginalis G3|Rep: Viral A-type inclusion
            protein, putative - Trichomonas vaginalis G3
          Length = 2345

 Score =  134 bits (324), Expect = 2e-29
 Identities = 297/1564 (18%), Positives = 633/1564 (40%), Gaps = 103/1564 (6%)

Query: 61   LENAALVSKRIKEHRKATAELLGRPFVPGISESLANTLKQKEILMEKIKQYKELSKRSST 120
            + NA   SK   E  K   +LL +     +++  ++  KQ + L E+    KE + +++ 
Sbjct: 509  MSNALEKSKNDVEAAKRENDLLQKK----LAQITSDLQKQIDALEEENGDLKEEANKANA 564

Query: 121  TIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKIN 180
               +               QL D       + +  N      +K K+ ET   DL +   
Sbjct: 565  DCAKAKEQLNKAIADTKK-QLADKEQTHEELLKNSNE-EKQGIKKKLNETAN-DLAKTKE 621

Query: 181  EKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFI-AMEAEWKDEKQRL 239
            +  Q+ E K+K T                  +   QQ + +++    AM A        L
Sbjct: 622  QLQQMAEEKDK-TQSKLDAEEGKRKNAENQLKLLSQQNSDLKDLIEQAMHAIGATNNDDL 680

Query: 240  LKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQS 299
            LK I++     S+L++A + +  ++ E+    + +A E  +              +A + 
Sbjct: 681  LKAIQNNASAQSTLDKACRNIGVSQAELPQTLTNIANE-RKHMMSTLQVPEKGGDIASKV 739

Query: 300  IEPSCEEKTEIEEKGSLEIANMT-ELTKKIELLEH---LNCQIRQTNKELENKLATMGTE 355
               + + K  +EE  +L+  N         E   +   L   ++Q N+  E+++      
Sbjct: 740  DSLANQYKENLEELNNLKAYNKKFGKAFNFEFNPNETTLKNAVKQGNQAHEDRVCAQEIV 799

Query: 356  SKAVSSPSKKGSPLISRKSGRNTASK-MKSPWSQLSSETLNQDTDKKINKNEIAKLEMVI 414
             +A        +P+ + +   NT  K +     +  ++   +    K  +++I +L   +
Sbjct: 800  GRAQKLGYIGDNPIEASEYITNTVKKQLGDELDRAKNDNNAKQAQIKGMQDKIDELSEKL 859

Query: 415  QSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQL---QLEHQQHMEGP--SLIH-V 468
             +  K   DK+   + K             K   IA+    + E +  +EG   ++I  +
Sbjct: 860  DTATKTSDDKDKDYAAKMKAAEKQIKELQAKADDIAKEFTDEAESKNQLEGKLKAIIGAL 919

Query: 469  GTNTEDVN-EIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLND--EIDAANKN 525
            G +  D   + A++  Q  +E ++ +  + V +       A + +  LN+  ++ +  ++
Sbjct: 920  GVSDPDTGLQAAQMSFQKAKEFDENLAIIKVDE-----DQAVDTVANLNNKGQVLSQIQD 974

Query: 526  MIKVKSNHKLKLKQMQKTIDNFSKVSD--SNKEIVRLTEELHHLSQKVAELEEEKGNLQL 583
            MI   ++ K+ +  ++K +D  +KV         V L E +  +     +L+ E  N Q 
Sbjct: 975  MISTPNSDKV-VPAIKKLVDERNKVEQFLETNGAVPLPEAVEDVVMNEKKLQFELENAQN 1033

Query: 584  HLVD-YDSGRMI----------ESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHI 632
             +   YD+  MI          +S ++K + +    A+    AI  +  Q   L      
Sbjct: 1034 IIKKFYDANGMIMPQPGASPTKKSQIFKDIEKQREQAQENRDAIIDVLEQAHKLGYGASS 1093

Query: 633  LQQKYDEVEDKLADISQLQSD---QVCSEIKSVHLEEQIDALSASKKELALV-IENLKLD 688
            L +  + +++ +    + + D   Q  S+ K   L+E I+ L +   +LA    +  KL 
Sbjct: 1094 LDEAVEAIKNAVQKDEKKKQDALQQQFSQEKDALLDE-IEELQSQNAKLADENAQQQKLL 1152

Query: 689  KEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQ 748
             +Q    + D + +  ++ NK +N    N+   +K  +  A+K+ ++ A++ +E++    
Sbjct: 1153 NDQ-EKALADADEEISELQNKAENQ-SSNIASKNKENEAIAKKLEDIKAELQNEKKEHEA 1210

Query: 749  TQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQE 808
             +   D K+  +DL  +  + E   +      LEE I  +  +  + ++  D L   L  
Sbjct: 1211 DKAAADKKL--KDLQQQKAQQE-QDFAEEKADLEEQIQNLTKQNENAKKDNDALAGKLAA 1267

Query: 809  KQKAYSEYTIQED--ELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQ 866
             ++   + TI +D  E+ N    + D  +  +++  E      +L+ K + L       Q
Sbjct: 1268 TEEELKQ-TIAKDNEEIENAKKTINDLGKQAKQKDKEAASTVTDLEDKIEDLQNNLNQSQ 1326

Query: 867  ISLSDMQQHYNALVEKANRTDLA-ESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEI 925
                ++ +   AL E+ N+ D   E+E  K Q QL+ L+    +   ++  L  +K +EI
Sbjct: 1327 RDNDNLNKKVAALQEEQNQKDQQYEAELEKLQNQLKQLQQQKAQQEQDNNKLNDEKDEEI 1386

Query: 926  EDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMN 985
            + L    N +IE   R     N+  +K  E   Q + +  +  N I NLN  +E L K N
Sbjct: 1387 QQL----NKEIEEMQR----AND--QKIREMNKQAKQKDDDNNNQIMNLNDQIEALKK-N 1435

Query: 986  LELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSD 1045
            L    K  +    +  +  E+  N I K N  ++   ++I  LN++    +    S + +
Sbjct: 1436 LSQAQKDNEGLNKKLAEKEEELSNVIAKDNDEIENAKKQINDLNKQNKQKEKDSNSQIEE 1495

Query: 1046 YESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIK-ELKETKLTFEM 1104
             + ++      L  ++ +++   K+L D +    E       + DQ+  +L E     + 
Sbjct: 1496 LKDQIDVLENTLAQVQRDLETTQKKLADKEAELAETIAKGNAEQDQLNNQLNELNKQGKQ 1555

Query: 1105 NIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKL 1164
               K     +S   E +      ++            L+ ++EE        L +  AK 
Sbjct: 1556 K-DKENAAAMSQAKEQIEQLQAALNQAQKDNDNANKKLQAKDEE--------LNQTIAKD 1606

Query: 1165 NTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSI 1224
            N EL++   +  Q   LN +    D  N +QI  L+ ++ +L  +   LL     L   +
Sbjct: 1607 NDELEK---QRKQYNDLNKQKQQKDKENADQIQNLQDQIAKLQKQGAQLLKDNENLGKKL 1663

Query: 1225 SSAVDQRGFEIAELWKQHLAQRE--ADFQK-TEHELRVQLSAFESKYEQLLDSVQSSTQE 1281
            +   ++    +A+  ++   Q++  +D  K ++ + R   +      EQ+ D  +S  Q 
Sbjct: 1664 NEKEEELKQTVAKDTEEMEKQKKTISDLNKQSKQKDRENGNQVMDLQEQIEDLQKSLAQA 1723

Query: 1282 ETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXX 1341
            + +  V  +++ +LQN+ + + +  ++  E   + I  +   ++++E EK          
Sbjct: 1724 QRDNEVLGKKIGNLQNEQEQENQEHKDAIENLENQIKALNQQKNQVEQEKNKQKEQQDDE 1783

Query: 1342 XXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAK 1401
                     DL+ + +   +  +Q + ++N + A L++              + NDAE K
Sbjct: 1784 IEQLKQQIEDLQKQAEINDKKHQQQVASLNGDVAGLQEK-------LEAMTQQKNDAEHK 1836

Query: 1402 VLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAI 1461
              +    L+  + E      E      + N    ++++++ E ++  E L  E       
Sbjct: 1837 AAQTKEDLDKVNQENEANKQEKDQLQKKLNQTAGDLQKRVKELQEENETLHEEAVKNNEQ 1896

Query: 1462 LRLKMHENANHYETMQKESE-IERVKLIEELNVKITESVSLNKQVAEL---NKALEEEVA 1517
            L+  + +     +  ++E + + R+   +ELN    E+  L +Q+A++    K  E ++A
Sbjct: 1897 LQRALSDVKKQLKEKEREHDNLSRIS-GDELNDLKRENEGLKEQLAKVTEDKKEAERQLA 1955

Query: 1518 KTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMN 1577
            +TN  +  LE    +   L D+  ++ + +    +K +K ++  +D K+  + +L+    
Sbjct: 1956 QTNNEKKDLEE---KFQKLADDKKDVDDKL----AKTEKELAKVNDEKKEAEGKLEELGK 2008

Query: 1578 KELL 1581
            K+ L
Sbjct: 2009 KDKL 2012



 Score =  126 bits (305), Expect = 4e-27
 Identities = 275/1496 (18%), Positives = 605/1496 (40%), Gaps = 156/1496 (10%)

Query: 147  LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXX 206
            L    ++K  A      ++  +   ++ LQ K++   + +EA  K  +            
Sbjct: 62   LKEITQQKQIAEQQATSQIASLNDQVMQLQGKLDNLSKQLEASQKKLSQTTSELGGELEQ 121

Query: 207  XXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFE 266
                  + +Q+M  +Q           DEK ++   +      + ++++ N  L   +++
Sbjct: 122  TKENNANLEQKMKDLQNQNAKNAQALNDEKDQIQGKLNETMKELDNVKQQNDSLN-KKYD 180

Query: 267  ISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTK 326
              +E+  L  ELE                 +Q ++ +  +KT  E+             K
Sbjct: 181  TDVEN--LKNELEATKALNGQN--------EQKLKDANAQKTAAEQ-------------K 217

Query: 327  KIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPW 386
             ++L +    Q  Q  +ELEN      T +K  ++  K     +  K+  +    ++   
Sbjct: 218  LVQLQQQYEDQTAQLKQELENNKRDNDTNAKKQATLQKDLENQL--KNANDEIETLEQRN 275

Query: 387  SQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKD 446
              L+++  N D     N + I +LE  ++ L KD    +                   KD
Sbjct: 276  KDLTAQKQNNDNK---NASRINELEDEVEKLTKDCETLKIKNGSLKKKLQAASQDNMNKD 332

Query: 447  TLIAQLQLEHQQHMEGPSLIH----VGTNTEDVN---EIAKVQEQLKQE------LNDEI 493
              + QL+ E++Q M+  +  +      TN E  N   +I ++Q+QL Q       LN  I
Sbjct: 333  EAMKQLRDENEQKMKEMNKQNKQKEQETNAEFQNLHDQIEQLQKQLAQSQRENDTLNKRI 392

Query: 494  ------KDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNF 547
                  K    K+  E+L+  E Q+ QL  +     + + K K  +   L++ Q+ +D  
Sbjct: 393  NNLQGDKATQDKEYAEELEKLENQLKQLQQQKQQTEQELSKQKEQNAQDLQKAQEQMDEM 452

Query: 548  SKVSDSN-----KEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYD-SGRMIESDVYKK 601
             K +D+N      +   L EEL    Q++   E++  +L       +       +D+   
Sbjct: 453  QKQNDANDKKNQAQAKALEEELEQAKQQLKNQEQKINDLNAQKTQVEQKAAQNNTDMSNA 512

Query: 602  MIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQ--LQSDQVCSEI 659
            + + +N  E   +   LL+ +   L Q    LQ++ D +E++  D+ +   +++  C++ 
Sbjct: 513  LEKSKNDVEAAKRENDLLQKK---LAQITSDLQKQIDALEEENGDLKEEANKANADCAKA 569

Query: 660  KSVHLEEQIDALSASKKELALVIENLKLDKEQLY-GTIKDLENDKEDIMNKLQNYIQENM 718
            K    E+   A++ +KK+LA        DKEQ +   +K+   +K+ I  KL     +  
Sbjct: 570  K----EQLNKAIADTKKQLA--------DKEQTHEELLKNSNEEKQGIKKKLNETANDLA 617

Query: 719  DLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRI 778
               ++L++M+ EK          + QSK+  + G   K +  +  ++ +  + S  K  I
Sbjct: 618  KTKEQLQQMAEEK---------DKTQSKLDAEEG---KRKNAENQLKLLSQQNSDLKDLI 665

Query: 779  CRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVE 838
             +   +I    +    L +      S      KA     + + EL   L  + +  + + 
Sbjct: 666  EQAMHAIGATNND--DLLKAIQNNASAQSTLDKACRNIGVSQAELPQTLTNIANERKHMM 723

Query: 839  KQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQT 898
              L   E       K + +  +  +NL+  L++++  YN    KA   +   +E+T    
Sbjct: 724  STLQVPEKGGDIASKVDSLANQYKENLE-ELNNLKA-YNKKFGKAFNFEFNPNETTLKNA 781

Query: 899  QLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVT 958
              +  +++  R+  +      QK   I D  IE +  I + +  KK L ++ ++      
Sbjct: 782  VKQGNQAHEDRVCAQEIVGRAQKLGYIGDNPIEASEYITNTV--KKQLGDELDRAKNDNN 839

Query: 959  QLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEIN-KLNAL 1017
              +AQ++  ++ I+ L+  ++   K + +    +  K +       E+ I E+  K + +
Sbjct: 840  AKQAQIKGMQDKIDELSEKLDTATKTSDDKDKDYAAKMKA-----AEKQIKELQAKADDI 894

Query: 1018 LKQKDEEIIALNQKINNAQVSYMSM-VSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQ 1076
             K+  +E  + NQ     +    ++ VSD ++ L       +  +E  + ++   +D  Q
Sbjct: 895  AKEFTDEAESKNQLEGKLKAIIGALGVSDPDTGLQAAQMSFQKAKEFDENLAIIKVDEDQ 954

Query: 1077 HNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXX 1136
              + +  L   +   + ++++      ++ P ++ ++    I+ + D+ N V+       
Sbjct: 955  AVDTVANL-NNKGQVLSQIQDM-----ISTPNSDKVV--PAIKKLVDERNKVE----QFL 1002

Query: 1137 XXXXXLKVQEEEEFIQERSVLQEQSAKLNTE-LQECYTKIIQLETLNTELTGHDVVNQEQ 1195
                 + + E  E +    V+ E+  +   E  Q    K      +     G     + Q
Sbjct: 1003 ETNGAVPLPEAVEDV----VMNEKKLQFELENAQNIIKKFYDANGMIMPQPGASPTKKSQ 1058

Query: 1196 I-NQLKSKLEQLNTENDNLLSTVAELR------SSISSAVD--QRGFEIAELWKQHLAQR 1246
            I   ++ + EQ     D ++  + +        SS+  AV+  +   +  E  KQ   Q+
Sbjct: 1059 IFKDIEKQREQAQENRDAIIDVLEQAHKLGYGASSLDEAVEAIKNAVQKDEKKKQDALQQ 1118

Query: 1247 EADFQKTEHELRVQLSAFESKYEQLLD--SVQSSTQEETNKIV--TMEQVTSLQNKLQDK 1302
            +  F + +  L  ++   +S+  +L D  + Q     +  K +    E+++ LQNK +++
Sbjct: 1119 Q--FSQEKDALLDEIEELQSQNAKLADENAQQQKLLNDQEKALADADEEISELQNKAENQ 1176

Query: 1303 EEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQM 1362
              ++ +  ++   +  ++E +++E+++EK                       + Q + + 
Sbjct: 1177 SSNIASKNKENEAIAKKLEDIKAELQNEKKEHEADKAAADKKLKDLQQQKAQQEQDFAEE 1236

Query: 1363 Q---EQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLE--LKD--SE 1415
            +   E+ I N+ ++N   KK +             +    AK  E     +  + D   +
Sbjct: 1237 KADLEEQIQNLTKQNENAKKDNDALAGKLAATEEELKQTIAKDNEEIENAKKTINDLGKQ 1296

Query: 1416 IYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYET 1475
              QK  E   T+T   D+ E+++  L + ++  ++L      ++A L+ + ++    YE 
Sbjct: 1297 AKQKDKEAASTVTDLEDKIEDLQNNLNQSQRDNDNL----NKKVAALQEEQNQKDQQYEA 1352

Query: 1476 ----MQKE-SEIERVKLIEE-----LNVKITESV-SLNKQVAELNKALEEEVAKTN-EMQ 1523
                +Q +  ++++ K  +E     LN +  E +  LNK++ E+ +A ++++ + N + +
Sbjct: 1353 ELEKLQNQLKQLQQQKAQQEQDNNKLNDEKDEEIQQLNKEIEEMQRANDQKIREMNKQAK 1412

Query: 1524 TALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKE 1579
               ++   +I+ LND+I  L    + + S+ QK     +     ++E+L N + K+
Sbjct: 1413 QKDDDNNNQIMNLNDQIEAL----KKNLSQAQKDNEGLNKKLAEKEEELSNVIAKD 1464



 Score =  118 bits (283), Expect = 2e-24
 Identities = 292/1463 (19%), Positives = 581/1463 (39%), Gaps = 141/1463 (9%)

Query: 212  EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLE---------- 261
            ++ +Q+M +M +     E E   E Q L   IE    +++  +  N  L           
Sbjct: 340  DENEQKMKEMNKQNKQKEQETNAEFQNLHDQIEQLQKQLAQSQRENDTLNKRINNLQGDK 399

Query: 262  -AARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIAN 320
                 E + E  KL  +L+Q                +Q+ +   + + +++E      AN
Sbjct: 400  ATQDKEYAEELEKLENQLKQLQQQKQQTEQELSKQKEQNAQDLQKAQEQMDEMQKQNDAN 459

Query: 321  MTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISR---KSGRN 377
              +   + + LE    Q +Q  K  E K+  +  +   V   + + +  +S    KS  +
Sbjct: 460  DKKNQAQAKALEEELEQAKQQLKNQEQKINDLNAQKTQVEQKAAQNNTDMSNALEKSKND 519

Query: 378  T-ASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXX 436
              A+K ++   Q     +  D  K+I+  E    ++  +  NK   D      + +    
Sbjct: 520  VEAAKRENDLLQKKLAQITSDLQKQIDALEEENGDLK-EEANKANADCAKAKEQLNKAIA 578

Query: 437  XXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDV 496
                    K+    +L     +  +G   I    N E  N++AK +EQL+Q   ++ K  
Sbjct: 579  DTKKQLADKEQTHEELLKNSNEEKQG---IKKKLN-ETANDLAKTKEQLQQMAEEKDKTQ 634

Query: 497  NVKDLIE-KLKSAEEQI---TQLNDEI-DAANKNMIKV-KSNHKLKLKQMQKTIDNFSKV 550
            +  D  E K K+AE Q+   +Q N ++ D   + M  +  +N+   LK +Q   +N S  
Sbjct: 635  SKLDAEEGKRKNAENQLKLLSQQNSDLKDLIEQAMHAIGATNNDDLLKAIQ---NNASAQ 691

Query: 551  SDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEM-ENLA 609
            S  +K    +      L Q +  +  E+ ++   L   + G  I S V     +  ENL 
Sbjct: 692  STLDKACRNIGVSQAELPQTLTNIANERKHMMSTLQVPEKGGDIASKVDSLANQYKENLE 751

Query: 610  E-TRLKAISLLESQKFDL------VQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSV 662
            E   LKA +    + F+           + ++Q     ED++     +   Q    I   
Sbjct: 752  ELNNLKAYNKKFGKAFNFEFNPNETTLKNAVKQGNQAHEDRVCAQEIVGRAQKLGYIGDN 811

Query: 663  HLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLT- 721
             +E      +  KK+L   ++  K D       IK +++  +++  KL    + + D   
Sbjct: 812  PIEASEYITNTVKKQLGDELDRAKNDNNAKQAQIKGMQDKIDELSEKLDTATKTSDDKDK 871

Query: 722  DKLEKMSA--EKISELLAKINH-------EEQSKIQTQFGIDAKI-----QERDLYIENI 767
            D   KM A  ++I EL AK +        E +SK Q +  + A I      + D  ++  
Sbjct: 872  DYAAKMKAAEKQIKELQAKADDIAKEFTDEAESKNQLEGKLKAIIGALGVSDPDTGLQAA 931

Query: 768  ESELSKYKSRICRLEESIAVM---EDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELV 824
            +    K K      +E++A++   ED+        +  G  L + Q   S  T   D++V
Sbjct: 932  QMSFQKAKE----FDENLAIIKVDEDQAVDTVANLNNKGQVLSQIQDMIS--TPNSDKVV 985

Query: 825  NRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKAN 884
              +  L+D    VE Q LE        +    +++ E + LQ  L + Q       + AN
Sbjct: 986  PAIKKLVDERNKVE-QFLETNGAVPLPEAVEDVVMNEKK-LQFELENAQNIIKKFYD-AN 1042

Query: 885  RTDLAE--SESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRD 942
               + +  +  TK     +D+E   ++   E++  I+   ++   L    ++ ++ A+  
Sbjct: 1043 GMIMPQPGASPTKKSQIFKDIEKQREQ-AQENRDAIIDVLEQAHKLGYGASS-LDEAVEA 1100

Query: 943  KKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQ-----Q 997
             K   +K EK  +     +A  Q++    + L   +EEL   N +L D++ Q+Q     Q
Sbjct: 1101 IKNAVQKDEKKKQ-----DALQQQFSQEKDALLDEIEELQSQNAKLADENAQQQKLLNDQ 1155

Query: 998  TQSPDYTEQYINEI-NKL-----NALLKQKDEEIIA-----LNQKINNAQVSYMS----- 1041
             ++    ++ I+E+ NK      N   K K+ E IA     +  ++ N +  + +     
Sbjct: 1156 EKALADADEEISELQNKAENQSSNIASKNKENEAIAKKLEDIKAELQNEKKEHEADKAAA 1215

Query: 1042 --MVSDYESKLAQ----FTTKLENMEEEMQRVSKQLLDSKQHN-----------EELQIL 1084
               + D + + AQ    F  +  ++EE++Q ++KQ  ++K+ N           EEL+  
Sbjct: 1216 DKKLKDLQQQKAQQEQDFAEEKADLEEQIQNLTKQNENAKKDNDALAGKLAATEEELKQT 1275

Query: 1085 VREQDDQIKELKET--KLTFEMNIPKTEGMIISSTIEPMSDDA-NNVDXXXXXXXXXXXX 1141
            + + +++I+  K+T   L  +      E     + +E   +D  NN++            
Sbjct: 1276 IAKDNEEIENAKKTINDLGKQAKQKDKEAASTVTDLEDKIEDLQNNLNQSQRDNDNLNKK 1335

Query: 1142 LKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKS 1201
            +   +EE+  Q+    + +  KL  +L++   +  Q E  N +L        E+I QL  
Sbjct: 1336 VAALQEEQN-QKDQQYEAELEKLQNQLKQLQQQKAQQEQDNNKLNDE---KDEEIQQLNK 1391

Query: 1202 KLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQRE--ADFQKTEHELRV 1259
            ++E++   ND     + E+        D    +I  L  Q  A ++  +  QK    L  
Sbjct: 1392 EIEEMQRANDQ---KIREMNKQAKQKDDDNNNQIMNLNDQIEALKKNLSQAQKDNEGLNK 1448

Query: 1260 QLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQ 1319
            +L+    K E+L + +     E  N     +Q+  L  + + KE+   +  E+  D   Q
Sbjct: 1449 KLA---EKEEELSNVIAKDNDEIEN---AKKQINDLNKQNKQKEKDSNSQIEELKD---Q 1499

Query: 1320 IEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKK 1379
            I++L + +   +                    +   N    Q+  Q    +NE N Q K+
Sbjct: 1500 IDVLENTLAQVQRDLETTQKKLADKEAELAETIAKGNAEQDQLNNQ----LNELNKQGKQ 1555

Query: 1380 SSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQ 1439
                          ++   +A + +     +  + ++  K  E   T+ + NDE E  R+
Sbjct: 1556 KDKENAAAMSQAKEQIEQLQAALNQAQKDNDNANKKLQAKDEELNQTIAKDNDELEKQRK 1615

Query: 1440 QLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESV 1499
            Q  +  K+ +    E   ++  L+ ++ +       + K++E    K + E   ++ ++V
Sbjct: 1616 QYNDLNKQKQQKDKENADQIQNLQDQIAKLQKQGAQLLKDNE-NLGKKLNEKEEELKQTV 1674

Query: 1500 SLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVS 1559
            + + +  E  K    ++ K ++ Q   EN   +++ L ++I +LQ  + A + +  + + 
Sbjct: 1675 AKDTEEMEKQKKTISDLNKQSK-QKDRENGN-QVMDLQEQIEDLQKSL-AQAQRDNEVLG 1731

Query: 1560 FASDTKQGRDEQLDNTMNKELLD 1582
                  Q   EQ +N  +K+ ++
Sbjct: 1732 KKIGNLQNEQEQ-ENQEHKDAIE 1753



 Score =  111 bits (268), Expect = 1e-22
 Identities = 232/1139 (20%), Positives = 473/1139 (41%), Gaps = 99/1139 (8%)

Query: 140  QLGDVTHLSNTIKEKDNALS-VLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXX 198
            Q+ ++T  +   K+ ++AL+  L    + ++ TI    E+I    + I    K       
Sbjct: 1243 QIQNLTKQNENAKKDNDALAGKLAATEEELKQTIAKDNEEIENAKKTINDLGKQAKQKDK 1302

Query: 199  XXXXXXXXXXXXXEDTKQQMTKMQ---ENFIAMEAEWKDEKQRLLKDIESKDVRISSLEE 255
                         ED +  + + Q   +N     A  ++E+ +  KD +  +  +  L+ 
Sbjct: 1303 EAASTVTDLEDKIEDLQNNLNQSQRDNDNLNKKVAALQEEQNQ--KD-QQYEAELEKLQN 1359

Query: 256  ANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGS 315
              K L+  + +   +++KL  E ++                 Q I    ++  + ++  +
Sbjct: 1360 QLKQLQQQKAQQEQDNNKLNDEKDEEIQQLNKEIEEMQRANDQKIREMNKQAKQKDDDNN 1419

Query: 316  LEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTE-SKAVSSPSKKGSPLISRKS 374
             +I N+ +   +IE L+    Q ++ N+ L  KLA    E S  ++  + +      + +
Sbjct: 1420 NQIMNLND---QIEALKKNLSQAQKDNEGLNKKLAEKEEELSNVIAKDNDEIENAKKQIN 1476

Query: 375  GRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTX 434
              N  +K K   S    E L    D  + +N +A+++  +++  K L DKE  ++E    
Sbjct: 1477 DLNKQNKQKEKDSNSQIEELKDQID--VLENTLAQVQRDLETTQKKLADKEAELAE---- 1530

Query: 435  XXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIK 494
                      +D L  QL   ++Q  +         N   +++  +  EQL+  LN   K
Sbjct: 1531 --TIAKGNAEQDQLNNQLNELNKQGKQKDK-----ENAAAMSQAKEQIEQLQAALNQAQK 1583

Query: 495  DVNVKDLIEKLKSAEEQITQL----NDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFS-K 549
            D +  +  +KL++ +E++ Q     NDE++   K    +    + K K+    I N   +
Sbjct: 1584 DNDNAN--KKLQAKDEELNQTIAKDNDELEKQRKQYNDLNKQKQQKDKENADQIQNLQDQ 1641

Query: 550  VSDSNKEIVRLTEELHHLSQKVAELEEE-KGNLQLHLVDYDSGRMIESDVYKKMIEMENL 608
            ++   K+  +L ++  +L +K+ E EEE K  +     + +  +   SD+ K+  + +  
Sbjct: 1642 IAKLQKQGAQLLKDNENLGKKLNEKEEELKQTVAKDTEEMEKQKKTISDLNKQSKQKDR- 1700

Query: 609  AETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSV--HLEE 666
             E   + + L E Q  DL + L   Q+  + +  K+ ++ Q + +Q   E K    +LE 
Sbjct: 1701 -ENGNQVMDLQE-QIEDLQKSLAQAQRDNEVLGKKIGNL-QNEQEQENQEHKDAIENLEN 1757

Query: 667  QIDALSASKKELALVIENLKLDK----EQLYGTIKDLENDKEDIMNKLQNYIQE-NMD-- 719
            QI AL+  K ++       K  +    EQL   I+DL+   E    K Q  +   N D  
Sbjct: 1758 QIKALNQQKNQVEQEKNKQKEQQDDEIEQLKQQIEDLQKQAEINDKKHQQQVASLNGDVA 1817

Query: 720  -LTDKLEKMSAEKI-SELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSR 777
             L +KLE M+ +K  +E  A    E+  K+  +   +A  QE+D   + +       + R
Sbjct: 1818 GLQEKLEAMTQQKNDAEHKAAQTKEDLDKVNQEN--EANKQEKDQLQKKLNQTAGDLQKR 1875

Query: 778  ICRLEESIAVMEDRRYS----LERKADQLGSYLQEKQKAYSEYT-IQEDELVN------- 825
            +  L+E    + +        L+R    +   L+EK++ +   + I  DEL +       
Sbjct: 1876 VKELQEENETLHEEAVKNNEQLQRALSDVKKQLKEKEREHDNLSRISGDELNDLKRENEG 1935

Query: 826  ---RLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEK 882
               +LA + +  +  E+QL +  +E K+L++K Q L ++ +++   L+  ++    + ++
Sbjct: 1936 LKEQLAKVTEDKKEAERQLAQTNNEKKDLEEKFQKLADDKKDVDDKLAKTEKELAKVNDE 1995

Query: 883  ANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDL-EIEFN-TQIESAI 940
                +    E  K    + DL+  L R+  + Q    ++ +  + L E E N  Q +S +
Sbjct: 1996 KKEAEGKLEELGKKDKLVSDLDGQLARVKSQAQAAQDEQAQTRDKLKETEANLAQAQSQV 2055

Query: 941  RDKKVLNEKY-----EKNIEYVTQLEAQLQEYKNNIENL--NMNVEELNKMNLELID--K 991
             + ++  +K       K ++ + Q  + L+  ++++  +   M +E+L        D   
Sbjct: 2056 NNLQIFIDKLCAALSCKQVQAI-QTASNLKLLRDSLVKVFGEMTIEDLIVAFNSYNDSRN 2114

Query: 992  HVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLA 1051
             VQ + T   D+  + I+ I   N   +        + Q++          + +  S LA
Sbjct: 2115 QVQVELTSLRDFVAKIISTIT--NGAARVTFPMATEIQQRV--------IQIVEKSSILA 2164

Query: 1052 QFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEG 1111
            +   K  ++ E +QR           NE + + + +   +I + +E  L     I +T  
Sbjct: 2165 RNDRK--SVSEVLQRAGTVGYQGNDLNEAVDV-IADYAARI-QAQEKLLEIREEIDQTRK 2220

Query: 1112 MIISSTIEPMSDDA---NNVDXXXXXXXXXXXXLKVQEEEEFIQERSV---LQEQSAKLN 1165
            M+         D+A     ++             + +EEE   Q +S+   ++E   KL 
Sbjct: 2221 MLEKEVESRSQDNAASKKKLEEAHQRYAEAKAAARQKEEENASQIQSLEANIRELEDKLR 2280

Query: 1166 TE--LQECYTKIIQLETLNTELTGHDVVNQEQIN-QLKSKLEQLNTENDNLLSTVAELR 1221
             E  L+E  T+I Q +T +  L    + +QE    +L + L     E+  L++ + + R
Sbjct: 2281 VEKQLREEITRIGQGKTADMRLIKAKLSDQEFATIELINNLMAKERESSRLMANLRKAR 2339



 Score =  111 bits (267), Expect = 2e-22
 Identities = 274/1482 (18%), Positives = 585/1482 (39%), Gaps = 136/1482 (9%)

Query: 174  DLQEKI-NEKDQI--IEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEA 230
            DL+ ++ N  D+I  +E +NK  T                 ED  +++TK  E       
Sbjct: 256  DLENQLKNANDEIETLEQRNKDLTAQKQNNDNKNASRINELEDEVEKLTKDCETLKIKNG 315

Query: 231  EWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXX 290
              K + Q   +D  +KD  +  L + N   E    E++ ++ +  QE             
Sbjct: 316  SLKKKLQAASQDNMNKDEAMKQLRDEN---EQKMKEMNKQNKQKEQE---TNAEFQNLHD 369

Query: 291  XXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLA 350
                L KQ  +   E  T  +   +L+    T+  +  E LE L  Q++Q  ++ +    
Sbjct: 370  QIEQLQKQLAQSQRENDTLNKRINNLQGDKATQDKEYAEELEKLENQLKQLQQQKQQTEQ 429

Query: 351  TMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKL 410
             +  + +  +   +K    +     +N A+  K   +Q  ++ L ++ ++   K ++   
Sbjct: 430  ELSKQKEQNAQDLQKAQEQMDEMQKQNDANDKK---NQAQAKALEEELEQA--KQQLKNQ 484

Query: 411  EMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXG--------KDTL---IAQLQLEHQQH 459
            E  I  LN      E   ++ +T                    D L   +AQ+  + Q+ 
Sbjct: 485  EQKINDLNAQKTQVEQKAAQNNTDMSNALEKSKNDVEAAKRENDLLQKKLAQITSDLQKQ 544

Query: 460  MEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEI 519
            ++     + G   E+ N+      + K++LN  I D   K L +K ++ EE +   N+E 
Sbjct: 545  IDALEEEN-GDLKEEANKANADCAKAKEQLNKAIADTK-KQLADKEQTHEELLKNSNEEK 602

Query: 520  DAANKNMIKVKSN---HKLKLKQMQKTIDNF-SKVSDSNKEIVRLTEELHHLSQKVAELE 575
                K + +  ++    K +L+QM +  D   SK+     +      +L  LSQ+ ++L 
Sbjct: 603  QGIKKKLNETANDLAKTKEQLQQMAEEKDKTQSKLDAEEGKRKNAENQLKLLSQQNSDL- 661

Query: 576  EEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQEL-HILQ 634
            ++     +H +    G     D+ K +    +   T  KA   +   + +L Q L +I  
Sbjct: 662  KDLIEQAMHAI----GATNNDDLLKAIQNNASAQSTLDKACRNIGVSQAELPQTLTNIAN 717

Query: 635  QKYD-----EVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIE-NLKLD 688
            ++       +V +K  DI+  + D + ++ K  +LEE ++ L A  K+           +
Sbjct: 718  ERKHMMSTLQVPEKGGDIAS-KVDSLANQYKE-NLEE-LNNLKAYNKKFGKAFNFEFNPN 774

Query: 689  KEQLYGTIKDLENDKED------IMNKLQ--NYIQEN-MDLTDKLEKMSAEKISELLAKI 739
            +  L   +K      ED      I+ + Q   YI +N ++ ++ +     +++ + L + 
Sbjct: 775  ETTLKNAVKQGNQAHEDRVCAQEIVGRAQKLGYIGDNPIEASEYITNTVKKQLGDELDRA 834

Query: 740  ---NHEEQSKIQ-TQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSL 795
               N+ +Q++I+  Q  ID   ++ D   +  + +   Y +++   E+ I  ++ +   +
Sbjct: 835  KNDNNAKQAQIKGMQDKIDELSEKLDTATKTSDDKDKDYAAKMKAAEKQIKELQAKADDI 894

Query: 796  ERK-ADQLGS--YLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVE----KQLLEIEHEN 848
             ++  D+  S   L+ K KA        D      A  M   +  E      +++++ + 
Sbjct: 895  AKEFTDEAESKNQLEGKLKAIIGALGVSDPDTGLQAAQMSFQKAKEFDENLAIIKVDEDQ 954

Query: 849  -----KELQKKNQILLEENQNLQISLSD-MQQHYNALVEKANRTD--LAESESTKYQTQL 900
                   L  K Q+L +    +    SD +      LV++ N+ +  L  + +      +
Sbjct: 955  AVDTVANLNNKGQVLSQIQDMISTPNSDKVVPAIKKLVDERNKVEQFLETNGAVPLPEAV 1014

Query: 901  RDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQL 960
             D+  N K++  E +       K+  D       Q  ++   K  + +  EK  E   + 
Sbjct: 1015 EDVVMNEKKLQFELEN-AQNIIKKFYDANGMIMPQPGASPTKKSQIFKDIEKQREQAQEN 1073

Query: 961  EAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQ 1020
               + +       L      L++  +E I   VQK + +  D  +Q  ++  + +ALL  
Sbjct: 1074 RDAIIDVLEQAHKLGYGASSLDEA-VEAIKNAVQKDEKKKQDALQQQFSQ--EKDALL-D 1129

Query: 1021 KDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNE- 1079
            + EE+ + N K+ +       +++D E  LA    ++  ++ + +  S  +    + NE 
Sbjct: 1130 EIEELQSQNAKLADENAQQQKLLNDQEKALADADEEISELQNKAENQSSNIASKNKENEA 1189

Query: 1080 ----------ELQILVREQ-------DDQIKELKETKLTFEMNIPKTEGMIISSTIEPMS 1122
                      ELQ   +E        D ++K+L++ K   E +  + E   +   I+ ++
Sbjct: 1190 IAKKLEDIKAELQNEKKEHEADKAAADKKLKDLQQQKAQQEQDFAE-EKADLEEQIQNLT 1248

Query: 1123 DDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLN 1182
                N               + + ++   ++   ++     +N   ++   K  +  +  
Sbjct: 1249 KQNENAKKDNDALAGKLAATEEELKQTIAKDNEEIENAKKTINDLGKQAKQKDKEAASTV 1308

Query: 1183 TELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQ- 1241
            T+L       +++I  L++ L Q   +NDNL   VA L+   +    Q   E+ +L  Q 
Sbjct: 1309 TDL-------EDKIEDLQNNLNQSQRDNDNLNKKVAALQEEQNQKDQQYEAELEKLQNQL 1361

Query: 1242 -HLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQ 1300
              L Q++A  ++  ++L  +    + + +QL   ++   +    KI  M +    + K  
Sbjct: 1362 KQLQQQKAQQEQDNNKLNDEK---DEEIQQLNKEIEEMQRANDQKIREMNK--QAKQKDD 1416

Query: 1301 DKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYK 1360
            D    + NL +       QIE L+  +   +                    +  +N   +
Sbjct: 1417 DNNNQIMNLND-------QIEALKKNLSQAQKDNEGLNKKLAEKEEELSNVIAKDNDEIE 1469

Query: 1361 QMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKT 1420
              ++Q I ++N++N Q +K S            +++  E  + ++   LE    ++  K 
Sbjct: 1470 NAKKQ-INDLNKQNKQKEKDS---NSQIEELKDQIDVLENTLAQVQRDLETTQKKLADKE 1525

Query: 1421 HEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKES 1480
             E   T+ + N E + +  QL E  K+ +    +K+ E A    +  E     +    ++
Sbjct: 1526 AELAETIAKGNAEQDQLNNQLNELNKQGK----QKDKENAAAMSQAKEQIEQLQAALNQA 1581

Query: 1481 EIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEI 1540
            + +     ++L  K  E   LN+ +A+ N  LE++  + N++    + ++ E     D+I
Sbjct: 1582 QKDNDNANKKLQAKDEE---LNQTIAKDNDELEKQRKQYNDLNKQKQQKDKENA---DQI 1635

Query: 1541 TNLQNMV---RASSSKIQKHVSFASDTKQGRDEQLDNTMNKE 1579
             NLQ+ +   +   +++ K           ++E+L  T+ K+
Sbjct: 1636 QNLQDQIAKLQKQGAQLLKDNENLGKKLNEKEEELKQTVAKD 1677



 Score = 99.1 bits (236), Expect = 9e-19
 Identities = 149/754 (19%), Positives = 313/754 (41%), Gaps = 68/754 (9%)

Query: 838  EKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQ 897
            E+Q+ E+E E  EL+K   IL  ++  L+      ++H N+  E A +      E    +
Sbjct: 6    ERQINEMEAEIDELKKDIDILKTKHDALK------KKHKNSNDEHAEQLSQLRLEKDDLE 59

Query: 898  TQLRDLESNLKRITHEHQT--------LIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEK 949
             +L+++ +  K+I  +  T         ++Q + ++++L  +     +   +    L  +
Sbjct: 60   KKLKEI-TQQKQIAEQQATSQIASLNDQVMQLQGKLDNLSKQLEASQKKLSQTTSELGGE 118

Query: 950  YEKNIEYVTQLEAQLQEYKN----NIENLNMNVEEL-NKMN--LELIDKHVQKQQTQSPD 1002
             E+  E    LE ++++ +N    N + LN   +++  K+N  ++ +D   Q+  + +  
Sbjct: 119  LEQTKENNANLEQKMKDLQNQNAKNAQALNDEKDQIQGKLNETMKELDNVKQQNDSLNKK 178

Query: 1003 Y---TEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLEN 1059
            Y    E   NE+    AL  Q ++++   N +   A+   + +   YE + AQ   +LEN
Sbjct: 179  YDTDVENLKNELEATKALNGQNEQKLKDANAQKTAAEQKLVQLQQQYEDQTAQLKQELEN 238

Query: 1060 MEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIE 1119
             + +    +K+        ++L+  ++  +D+I+ L++            +    +S I 
Sbjct: 239  NKRDNDTNAKK---QATLQKDLENQLKNANDEIETLEQRNKDLTAQKQNNDNK-NASRIN 294

Query: 1120 PMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLE 1179
             + D+   +             LK ++ +   Q+     E   +L  E ++   ++ +  
Sbjct: 295  ELEDEVEKLTKDCETLKIKNGSLK-KKLQAASQDNMNKDEAMKQLRDENEQKMKEMNKQN 353

Query: 1180 TLNTELTGHDVVN-QEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAEL 1238
                + T  +  N  +QI QL+ +L Q   END L   +  L+    +  D+   E  E 
Sbjct: 354  KQKEQETNAEFQNLHDQIEQLQKQLAQSQRENDTLNKRINNLQGD-KATQDKEYAEELEK 412

Query: 1239 WKQHLAQREADFQKTEHEL---RVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSL 1295
             +  L Q +   Q+TE EL   + Q +    K ++ +D +Q   Q + N      Q  +L
Sbjct: 413  LENQLKQLQQQKQQTEQELSKQKEQNAQDLQKAQEQMDEMQK--QNDANDKKNQAQAKAL 470

Query: 1296 QNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTE 1355
            + +L+  ++ L+N ++K    IN +   ++++E +                      + E
Sbjct: 471  EEELEQAKQQLKNQEQK----INDLNAQKTQVEQKAAQNNTDMSNALEKSKNDVEAAKRE 526

Query: 1356 N--------QSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTH 1407
            N        Q    +Q+Q I  + EEN  LK+ +            ++N A A       
Sbjct: 527  NDLLQKKLAQITSDLQKQ-IDALEEENGDLKEEANKANADCAKAKEQLNKAIADT----- 580

Query: 1408 QLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMH 1467
            + +L D E   +THE    L   N+E + ++++L E    +   T E+  ++A  + K  
Sbjct: 581  KKQLADKE---QTHEE--LLKNSNEEKQGIKKKLNETANDLAK-TKEQLQQMAEEKDKTQ 634

Query: 1468 ENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVA------ELNKALEEEVAKTNE 1521
               +  E  +K +E  ++KL+ + N  + + +             +L KA++   +  + 
Sbjct: 635  SKLDAEEGKRKNAE-NQLKLLSQQNSDLKDLIEQAMHAIGATNNDDLLKAIQNNASAQST 693

Query: 1522 MQTALENQEIEIVTLNDEITNLQNMVRASSSKIQ 1555
            +  A  N  +    L   +TN+ N  +   S +Q
Sbjct: 694  LDKACRNIGVSQAELPQTLTNIANERKHMMSTLQ 727



 Score = 95.5 bits (227), Expect = 1e-17
 Identities = 136/754 (18%), Positives = 321/754 (42%), Gaps = 62/754 (8%)

Query: 639  EVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKD 698
            ++ +  A+I +L+ D    + K   L+++      S  E A  +  L+L+K+ L   +K+
Sbjct: 8    QINEMEAEIDELKKDIDILKTKHDALKKKH---KNSNDEHAEQLSQLRLEKDDLEKKLKE 64

Query: 699  LENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQ 758
            +   K+    +  + I     L D++ ++   K+  L  ++   ++   QT   +  +++
Sbjct: 65   ITQQKQIAEQQATSQIAS---LNDQVMQLQG-KLDNLSKQLEASQKKLSQTTSELGGELE 120

Query: 759  ERDLYIENIESELSKYKSRICRLEESIAVMEDR-RYSLERKADQLGSYLQEKQKAYSEYT 817
            +      N+E ++   +++  +  +++   +D+ +  L     +L +  Q+      +Y 
Sbjct: 121  QTKENNANLEQKMKDLQNQNAKNAQALNDEKDQIQGKLNETMKELDNVKQQNDSLNKKYD 180

Query: 818  IQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYN 877
               + L N L      +   E++L +   +    ++K   L++  Q  +   + ++Q   
Sbjct: 181  TDVENLKNELEATKALNGQNEQKLKDANAQKTAAEQK---LVQLQQQYEDQTAQLKQEL- 236

Query: 878  ALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIE 937
                + N+ D  ++ + K  T  +DLE+ LK    E +TL  Q+ K++   +   + +  
Sbjct: 237  ----ENNKRD-NDTNAKKQATLQKDLENQLKNANDEIETL-EQRNKDLTAQKQNNDNKNA 290

Query: 938  SAIRDKKVLNEKYEKNIEYVT--------QLEAQLQEYKNNIENLNMNVEELNKMNLELI 989
            S I + +   EK  K+ E +         +L+A  Q+  N  E +    +E  +   E+ 
Sbjct: 291  SRINELEDEVEKLTKDCETLKIKNGSLKKKLQAASQDNMNKDEAMKQLRDENEQKMKEMN 350

Query: 990  DKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESK 1049
             ++ QK+Q  + ++   + ++I +L   L Q   E   LN++INN Q    +   +Y  +
Sbjct: 351  KQNKQKEQETNAEFQNLH-DQIEQLQKQLAQSQRENDTLNKRINNLQGDKATQDKEYAEE 409

Query: 1050 LAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKT 1109
            L +   +L+ ++++ Q+  ++L  SKQ  +  Q L + Q+   +  K+     + N  + 
Sbjct: 410  LEKLENQLKQLQQQKQQTEQEL--SKQKEQNAQDLQKAQEQMDEMQKQNDANDKKN--QA 465

Query: 1110 EGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQ 1169
            +   +   +E       N +               Q+  +   +++ +++++A+ NT++ 
Sbjct: 466  QAKALEEELEQAKQQLKNQE---------------QKINDLNAQKTQVEQKAAQNNTDMS 510

Query: 1170 ECYTKIIQLETLNTELTGHDVVNQE--QI-NQLKSKLEQLNTENDNLLSTVAELRSSISS 1226
                K      +      +D++ ++  QI + L+ +++ L  EN +L     +  +  + 
Sbjct: 511  NALEK--SKNDVEAAKRENDLLQKKLAQITSDLQKQIDALEEENGDLKEEANKANADCAK 568

Query: 1227 AVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKI 1286
            A +Q    IA+  KQ LA +E   ++       +    + K  +  + + + T+E+  ++
Sbjct: 569  AKEQLNKAIADTKKQ-LADKEQTHEELLKNSNEEKQGIKKKLNETANDL-AKTKEQLQQM 626

Query: 1287 VTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXX 1346
               E+    Q+KL  +E   +N +       NQ+++L  +  D K               
Sbjct: 627  A--EEKDKTQSKLDAEEGKRKNAE-------NQLKLLSQQNSDLKDLIEQAMHAIGATNN 677

Query: 1347 XXXXDLRTENQSYKQMQEQSILNINEENAQLKKS 1380
                     N S +   +++  NI    A+L ++
Sbjct: 678  DDLLKAIQNNASAQSTLDKACRNIGVSQAELPQT 711



 Score = 67.3 bits (157), Expect = 3e-09
 Identities = 102/573 (17%), Positives = 242/573 (42%), Gaps = 44/573 (7%)

Query: 1043 VSDYESKLAQFTTKLENMEEEMQRVSKQLLDSK-QHNEELQILVREQDDQIKELKETKLT 1101
            +++ E+++ +    ++ ++ +   + K+  +S  +H E+L  L  E+DD  K+LKE  +T
Sbjct: 9    INEMEAEIDELKKDIDILKTKHDALKKKHKNSNDEHAEQLSQLRLEKDDLEKKLKE--IT 66

Query: 1102 FEMNIPKTEGMI-ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQ 1160
             +  I + +    I+S  + +      +D            L  Q   E   E    +E 
Sbjct: 67   QQKQIAEQQATSQIASLNDQVMQLQGKLDNLSKQLEASQKKLS-QTTSELGGELEQTKEN 125

Query: 1161 SAKLNTELQECYTKIIQ-LETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLL----S 1215
            +A L  ++++   +  +  + LN E    D + Q ++N+   +L+ +  +ND+L     +
Sbjct: 126  NANLEQKMKDLQNQNAKNAQALNDE---KDQI-QGKLNETMKELDNVKQQNDSLNKKYDT 181

Query: 1216 TVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSV 1275
             V  L++ + +     G    +L K   AQ+ A  QK   +L+ Q     ++ +Q L++ 
Sbjct: 182  DVENLKNELEATKALNGQNEQKL-KDANAQKTAAEQKLV-QLQQQYEDQTAQLKQELENN 239

Query: 1276 QSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADV--------------INQIE 1321
            +        K  T+++   L+N+L++  + +  L+++  D+              IN++E
Sbjct: 240  KRDNDTNAKKQATLQK--DLENQLKNANDEIETLEQRNKDLTAQKQNNDNKNASRINELE 297

Query: 1322 ILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSS 1381
                ++  +                    D   ++++ KQ+++++   + E N Q K+  
Sbjct: 298  DEVEKLTKDCETLKIKNGSLKKKLQAASQDNMNKDEAMKQLRDENEQKMKEMNKQNKQKE 357

Query: 1382 XXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQ-------KTHEYTITLTQRNDEF 1434
                        ++   + ++ +   + +  +  I         +  EY   L +  ++ 
Sbjct: 358  QETNAEFQNLHDQIEQLQKQLAQSQRENDTLNKRINNLQGDKATQDKEYAEELEKLENQL 417

Query: 1435 ENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVK 1494
            + ++QQ  + E+ +     +   +L   + +M E     +   K+++ +   L EEL   
Sbjct: 418  KQLQQQKQQTEQELSKQKEQNAQDLQKAQEQMDEMQKQNDANDKKNQAQAKALEEELEQA 477

Query: 1495 ITESVSLNKQVAELN---KALEEEVAKTN-EMQTALENQEIEIVTLNDEITNLQNMVRAS 1550
              +  +  +++ +LN     +E++ A+ N +M  ALE  + ++     E   LQ  +   
Sbjct: 478  KQQLKNQEQKINDLNAQKTQVEQKAAQNNTDMSNALEKSKNDVEAAKRENDLLQKKLAQI 537

Query: 1551 SSKIQKHVSFASDTKQGRDEQLDNTMNKELLDA 1583
            +S +QK +  A + + G  ++  N  N +   A
Sbjct: 538  TSDLQKQID-ALEEENGDLKEEANKANADCAKA 569


>UniRef50_A0CFL4 Cluster: Chromosome undetermined scaffold_176, whole
            genome shotgun sequence; n=1; Paramecium tetraurelia|Rep:
            Chromosome undetermined scaffold_176, whole genome
            shotgun sequence - Paramecium tetraurelia
          Length = 1842

 Score =  134 bits (324), Expect = 2e-29
 Identities = 284/1412 (20%), Positives = 594/1412 (42%), Gaps = 115/1412 (8%)

Query: 169  ETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAM 228
            E  +L     I    Q  E +N   T                 ++T++   + Q N +  
Sbjct: 283  EMVVLQKDSDIQALQQTTEVQNVQLTQSQSFNNDLQLSYQQETQNTEKDYNQNQINTLKQ 342

Query: 229  EAE--WKDEKQRLLKDIESKDVRISSLEEAN---KLLEAARFEISLEHSKLAQELEQXXX 283
            +      D K+  LK ++ K V+ S++ + N   +LLE    ++ L ++KL  E++Q   
Sbjct: 343  QIAKLTSDLKECELKHVQVKQVQESTISKLNHDVRLLEQKNEDLILHNNKLINEIKQNEL 402

Query: 284  XXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNK 343
                       +  Q I     E   +E    +E  N  E  K+  ++E LN Q+ Q +K
Sbjct: 403  IQQKEST----IICQKISEF--EIQLLESHHQIEDLNQ-EKQKQERVVEKLNLQM-QASK 454

Query: 344  ELENKLATMGTE-SKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKI 402
            ++++KL    T+    + S  K+   + S +S  ++ S  ++   +   + LN D     
Sbjct: 455  QIQSKLEEDITKYQNFLISHHKQLEAVTSNESSDSSDSSEETITEK--PQQLNFDALCTK 512

Query: 403  NKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQL-QLEHQQHME 461
               +I  +++ ++   K +   +  +  K              +  + +L QL+ +   +
Sbjct: 513  LTEQIRLVQLRLEIYEKQIKQYKQELHSKTVEIQKLFSENSDSNLKVQRLSQLQPKFDNQ 572

Query: 462  GPSLIHVGTNTEDVNE-IAKVQEQLKQELND-EIKDVNVKDLIEKLKSAEEQITQLNDEI 519
               +       E++++ I K Q QL +  N  +   ++ + L  K      QI Q++  I
Sbjct: 573  EAIIKQKDLTIENLSQQITKQQAQLHENENKLQQLQIDKETLNRKNVELSNQI-QIHHTI 631

Query: 520  DAANKNMIKVKSNHK-----LKLKQMQKTIDNF--SKVSDSNKEIVRLTEELHHLSQKVA 572
                KN +++ SN +     ++L   ++T  +      S+ N +I+  TEE  + +Q  +
Sbjct: 632  ----KNDLQISSNKEDPIQHIELMSSEQTSTSIFDQTFSNINYQILLFTEE--NTTQIKS 685

Query: 573  ELEEEKGNLQLHLV-DYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELH 631
             L  +  NL+ +L+   +  + ++  + K    ++NL E   + + + +   + +  +  
Sbjct: 686  ILSNKIDNLENNLLRTINKYQKLQEIIQKNYHNIQNLYEQSQQNL-IQKENLYQIENQKQ 744

Query: 632  ILQQK--YDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDK 689
             +Q++   +EV  +   ISQL++ Q    ++  +L +Q         +L  + E  K+D 
Sbjct: 745  QMQRQTLLEEVHQQTILISQLENQQQILSLQLKNLNQQNQDQKQVITQLQQLDEKQKIDD 804

Query: 690  EQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKIN--HEEQSKI 747
             Q+      LE  ++  +N+  + +++  +   +LE    +  +++ +K+N  +E + ++
Sbjct: 805  LQMGSNQTKLEELQQRTINQEAD-LKKASEQNTQLEIQVKDLNNQVQSKLNTINELRQEL 863

Query: 748  QTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQ 807
             +        Q   + ++  + ++ +  S    L +     +D +  L R+ + L   LQ
Sbjct: 864  DSLKNNQTGSQFDSIKLQQQQKQILELISNNTNLNQQ---SQDAQLRL-REMEALNLELQ 919

Query: 808  EKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQI 867
            ++    S+  + + E +N+L      +++  KQ L    +   LQK+   L  EN+ LQ 
Sbjct: 920  DRVNQLSKQGVSQKETINQL---QQQNQMEVKQNLTFLQQMDPLQKQIDHLTRENRKLQQ 976

Query: 868  SLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIED 927
            S +D ++ Y  L    +   +   +    Q Q++ LE  + +I ++ Q  I +K  E+ +
Sbjct: 977  SNNDFEKAYGKLPTYGSPRKVQNQD----QNQIKKLEDEILQIQYKFQQEIQEKNIELNN 1032

Query: 928  LEIEFNTQIESAIRDKKVLN-EKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNL 986
            ++ ++  Q+E  +R+ K+    K E+N   ++    Q Q   N +   N  +E  N    
Sbjct: 1033 IQKQYEQQLEE-VRELKLDEISKLEQNCVILSNQLKQQQVVNNELLQNNSQIERDNSQLS 1091

Query: 987  ELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDY 1046
            E I+K  ++Q+ QS +  ++ + + +++N   K      I LNQ I N Q+    +++D 
Sbjct: 1092 EEIEKLKKQQKLQSQN--QESLKQQDQINHECK-----YIELNQTIGNLQI----IINDQ 1140

Query: 1047 ESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNI 1106
              +L  F     ++EE+++    Q+ +  +  EEL         QIK+  ++  TF  N 
Sbjct: 1141 NLQLLNFKNHTLDLEEQIKHFEVQIQNLIKEKEEL--------CQIKDSNKSDETFTKNQ 1192

Query: 1107 PKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNT 1166
               E    +  +E + ++   +D             +V +++  +Q++ + Q Q      
Sbjct: 1193 QNEELDSQNQLMEQLKNEQFILD-------------QVNQDKLKLQQQQIEQGQLIHQQQ 1239

Query: 1167 ELQEC-YTKIIQLETLNTELTGHDVVNQEQINQLKS-KLEQLNTENDNLLSTVAELRSSI 1224
            ++ EC   +I +L  + +        + + I++L+S + EQL            EL+   
Sbjct: 1240 QVIECQQVEIKRLTLIESGSVEQKKESDQNISKLQSNQAEQLLPVQQEEFQ--VELKQK- 1296

Query: 1225 SSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETN 1284
               ++ +  EI EL KQ L Q      + E +L+    A     E  +  +Q+  Q +  
Sbjct: 1297 QKQIEAKDIEIHEL-KQKLYQNLQLNNELEQQLK-DKQAISIALENEIKQLQNVNQTQLQ 1354

Query: 1285 KIVTMEQVTSLQ-NKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXX 1343
            KI  + Q       +++++++ L N  E+ A + ++   ++  +   K+           
Sbjct: 1355 KITELNQDFQRSFEQVEEQKQTLTNQSEQNALLESKCNQMQQNV--MKIQTQNNSLIQIN 1412

Query: 1344 XXXXXXXDLRTE-NQSYKQMQEQSI-LNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAK 1401
                   + +   N    Q QEQS  + +++ N QL+                  + E K
Sbjct: 1413 QQLESTLEQQQHVNAQIIQKQEQSFQIQLDKLNIQLEDQQNQLKLLQQENGEYKQEIE-K 1471

Query: 1402 VLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAI 1461
            ++    Q E        K +E    L Q   E +   Q+L++   R E L  E ++E+  
Sbjct: 1472 IMNDQKQWE------QNKLNE----LVQVKKESQGQIQKLMDQISRAEGLNVEHQNEI-- 1519

Query: 1462 LRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNE 1521
              L+M +N       +K+  I    +IE+L +KI  +     ++   NKAL EE A   E
Sbjct: 1520 --LEM-DNVIKKLIQEKDKNINN-DMIEQLQIKIKMNEEQIGRLLMTNKALMEENAHLQE 1575

Query: 1522 -MQTALENQEIEIVTLNDEITNLQNMVRASSS 1552
             ++  L +      + N    N +N V   S+
Sbjct: 1576 QIKDDLNSSFCSNASQNCATKNQENEVSLPSN 1607



 Score =  120 bits (288), Expect = 4e-25
 Identities = 275/1457 (18%), Positives = 617/1457 (42%), Gaps = 128/1457 (8%)

Query: 156  NALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTK 215
            N  ++L+   K     I  LQ+ I   ++ IEA N+                    ED +
Sbjct: 5    NNEALLKQVNKNQTLLIQKLQDDIELLNEEIEASNQQIDTLKSQHHISLSQQQSIIEDLR 64

Query: 216  QQMTKMQENFIAMEAEWKDE--KQRLLK---DIESKDVR--ISSLEEANKLLEAARFEIS 268
             +    Q+  + +++++     + +LL+   D ++K  +  I  L++  KL      +  
Sbjct: 65   SECQNYQQQNMELQSKFTQSVLQNQLLQSKYDKKNKQYKDQIVELKQQIKLSHLKNQDYQ 124

Query: 269  LEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCE-EKTEIEEKGSLE-IANMTE-LT 325
             +  +L + L+               L +Q+ +     +  +++ +  +E   N+ +   
Sbjct: 125  RDILELRKSLDNNKLEICKLIDNSTLLNEQNKQLKANLDLQQVDYENKIEQYQNLIQDKD 184

Query: 326  KKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSP 385
            ++I L+ + N  + +  +++E       +    + +  K+   L+ + S     + +   
Sbjct: 185  EEITLIINENGVLNRNLEQMEKSANLSESLHSQIDTLQKQNQNLLIQLSDLQNHNTLLRQ 244

Query: 386  WSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGK 445
              QL S  +   +     + + A  +    ++N++ V +E V+ +KD+           +
Sbjct: 245  QLQLQSSEIQVSSSSLQLQLQSAPQQQTQDAMNRN-VQQEMVVLQKDSDIQALQQTTEVQ 303

Query: 446  DTLIAQ-------LQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELND-EIKDVN 497
            +  + Q       LQL +QQ  +     +   N   +N + +   +L  +L + E+K V 
Sbjct: 304  NVQLTQSQSFNNDLQLSYQQETQNTEKDY---NQNQINTLKQQIAKLTSDLKECELKHVQ 360

Query: 498  VKDL----IEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDS 553
            VK +    I KL      + Q N+++   N  +I     ++L ++Q + TI    K+S+ 
Sbjct: 361  VKQVQESTISKLNHDVRLLEQKNEDLILHNNKLINEIKQNEL-IQQKESTII-CQKISEF 418

Query: 554  NKEIVRLTEELHHLSQKVAELEE--EKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAET 611
              +++    ++  L+Q+  + E   EK NLQ+      + + I+S + + + + +N   +
Sbjct: 419  EIQLLESHHQIEDLNQEKQKQERVVEKLNLQMQ-----ASKQIQSKLEEDITKYQNFLIS 473

Query: 612  RLKAISLLESQKFDLVQELHILQQKYDEVEDKLADI-SQLQSDQVCSEI-KSVHLEE-QI 668
              K +  + S +              D  E+ + +   QL  D +C+++ + + L + ++
Sbjct: 474  HHKQLEAVTSNESS---------DSSDSSEETITEKPQQLNFDALCTKLTEQIRLVQLRL 524

Query: 669  DALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMS 728
            +      K+    + +  ++ ++L+    D  N K   +++LQ    +N +   K + ++
Sbjct: 525  EIYEKQIKQYKQELHSKTVEIQKLFSENSD-SNLKVQRLSQLQPKF-DNQEAIIKQKDLT 582

Query: 729  AEKISELLAKIN---HEEQSKIQTQFGIDAKIQERDLYIENIE-SELSKYKSRICRLEES 784
             E +S+ + K     HE ++K+Q Q  ID +   R    +N+E S   +    I    + 
Sbjct: 583  IENLSQQITKQQAQLHENENKLQ-QLQIDKETLNR----KNVELSNQIQIHHTIKNDLQI 637

Query: 785  IAVMEDRRYSLE-RKADQLGSYLQEKQKAYSEYTI---QEDELVNRLAVLMDHDRVVEKQ 840
             +  ED    +E   ++Q  + + ++  +   Y I    E+      ++L +    +E  
Sbjct: 638  SSNKEDPIQHIELMSSEQTSTSIFDQTFSNINYQILLFTEENTTQIKSILSNKIDNLENN 697

Query: 841  LLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQL 900
            LL   ++ ++LQ   +I+ +   N+Q      QQ+   L++K N   L + E+ K Q Q 
Sbjct: 698  LLRTINKYQKLQ---EIIQKNYHNIQNLYEQSQQN---LIQKEN---LYQIENQKQQMQR 748

Query: 901  RDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQL 960
            + L   L+ + H+   LI Q + + + L ++            K LN++ +   + +TQL
Sbjct: 749  QTL---LEEV-HQQTILISQLENQQQILSLQL-----------KNLNQQNQDQKQVITQL 793

Query: 961  EAQLQEYKNNIENLNMN-----VEELNK--MNLELIDKHVQKQQTQSPDYTEQYINEI-N 1012
            + QL E K  I++L M      +EEL +  +N E   K   +Q TQ     +   N++ +
Sbjct: 794  Q-QLDE-KQKIDDLQMGSNQTKLEELQQRTINQEADLKKASEQNTQLEIQVKDLNNQVQS 851

Query: 1013 KLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLL 1072
            KLN + + + +E+ +L      +Q   + +    + ++ +  +   N+ ++ Q    +L 
Sbjct: 852  KLNTINELR-QELDSLKNNQTGSQFDSIKL-QQQQKQILELISNNTNLNQQSQDAQLRLR 909

Query: 1073 DSKQHNEELQILVREQDDQIKELKET--------KLTFEMNIPKTEGMI-ISSTIEPMSD 1123
            + +  N ELQ  V +   Q    KET        ++  + N+   + M  +   I+ ++ 
Sbjct: 910  EMEALNLELQDRVNQLSKQGVSQKETINQLQQQNQMEVKQNLTFLQQMDPLQKQIDHLTR 969

Query: 1124 DANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQ-LETLN 1182
            +   +             L        +Q +   Q Q  KL  E+ +   K  Q ++  N
Sbjct: 970  ENRKLQQSNNDFEKAYGKLPTYGSPRKVQNQD--QNQIKKLEDEILQIQYKFQQEIQEKN 1027

Query: 1183 TELTGHDVVNQEQINQLKS-KLEQLNTENDN--LLSTVAELRSSISSAVDQRGFEIAELW 1239
             EL       ++Q+ +++  KL++++    N  +LS   + +  +++ + Q   +I    
Sbjct: 1028 IELNNIQKQYEQQLEEVRELKLDEISKLEQNCVILSNQLKQQQVVNNELLQNNSQI---- 1083

Query: 1240 KQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQN-K 1298
            ++  +Q   + +K + + ++Q    ES  +Q   + +    E    I  ++ + + QN +
Sbjct: 1084 ERDNSQLSEEIEKLKKQQKLQSQNQESLKQQDQINHECKYIELNQTIGNLQIIINDQNLQ 1143

Query: 1299 LQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQS 1358
            L + + H  +L+E+      QI+ L  E E+                     +L ++NQ 
Sbjct: 1144 LLNFKNHTLDLEEQIKHFEVQIQNLIKEKEELCQIKDSNKSDETFTKNQQNEELDSQNQL 1203

Query: 1359 YKQMQ-EQSILN-INEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEI 1416
             +Q++ EQ IL+ +N++  +L++               +   + ++  LT  L    S  
Sbjct: 1204 MEQLKNEQFILDQVNQDKLKLQQQQIEQGQLIHQQQQVIECQQVEIKRLT--LIESGSVE 1261

Query: 1417 YQKTHEYTITLTQRN--DEFENVRQQLVEYEKRIEDLTYE-KESELAILRLKMHENAN-H 1472
             +K  +  I+  Q N  ++   V+Q+  + E + +    E K+ E+  L+ K+++N   +
Sbjct: 1262 QKKESDQNISKLQSNQAEQLLPVQQEEFQVELKQKQKQIEAKDIEIHELKQKLYQNLQLN 1321

Query: 1473 YETMQKESEIERVKLIEELNVKITESVSLNK--QVAELNKALEEEVAKTNEMQTALENQE 1530
             E  Q+  + + + +  E  +K  ++V+  +  ++ ELN+  +    +  E +  L NQ 
Sbjct: 1322 NELEQQLKDKQAISIALENEIKQLQNVNQTQLQKITELNQDFQRSFEQVEEQKQTLTNQS 1381

Query: 1531 IEIVTLNDEITNLQNMV 1547
             +   L  +   +Q  V
Sbjct: 1382 EQNALLESKCNQMQQNV 1398



 Score =  118 bits (283), Expect = 2e-24
 Identities = 238/1231 (19%), Positives = 534/1231 (43%), Gaps = 119/1231 (9%)

Query: 392  ETLNQDTDKKINK--NEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLI 449
            + L QD D++I    NE   L   ++ + K     E + S+ DT              L 
Sbjct: 177  QNLIQDKDEEITLIINENGVLNRNLEQMEKSANLSESLHSQIDTLQKQNQNLLIQLSDLQ 236

Query: 450  AQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAE 509
                L  QQ     S I V +++  +   +  Q+Q +  +N  ++    ++++   K ++
Sbjct: 237  NHNTLLRQQLQLQSSEIQVSSSSLQLQLQSAPQQQTQDAMNRNVQ----QEMVVLQKDSD 292

Query: 510  EQITQLNDEIDAANKNMIKVKS-NHKLKLKQMQKTID-----NFSKVSDSNKEIVRLTE- 562
             Q  Q   E+   N  + + +S N+ L+L   Q+T +     N ++++   ++I +LT  
Sbjct: 293  IQALQQTTEVQ--NVQLTQSQSFNNDLQLSYQQETQNTEKDYNQNQINTLKQQIAKLTSD 350

Query: 563  ----ELHHLSQKVAE-------------LEEEKGNLQLH----LVDYDSGRMIESD---- 597
                EL H+  K  +             LE++  +L LH    + +     +I+      
Sbjct: 351  LKECELKHVQVKQVQESTISKLNHDVRLLEQKNEDLILHNNKLINEIKQNELIQQKESTI 410

Query: 598  VYKKMIEME-NLAETRLKAISL-LESQKFD-LVQELHILQQKYDEVEDKLA-DISQLQSD 653
            + +K+ E E  L E+  +   L  E QK + +V++L++  Q   +++ KL  DI++ Q+ 
Sbjct: 411  ICQKISEFEIQLLESHHQIEDLNQEKQKQERVVEKLNLQMQASKQIQSKLEEDITKYQNF 470

Query: 654  QVC--SEIKSVHLEEQIDALSASKKELALVIENLKLDK--EQLYGTIKDLENDKEDIMNK 709
             +    ++++V   E  D+  +S++ +    + L  D    +L   I+ ++   E    +
Sbjct: 471  LISHHKQLEAVTSNESSDSSDSSEETITEKPQQLNFDALCTKLTEQIRLVQLRLEIYEKQ 530

Query: 710  LQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQF-GIDAKIQERDLYIENIE 768
            ++ Y QE    T +++K+ +E  S+   K+  +  S++Q +F   +A I+++DL IEN+ 
Sbjct: 531  IKQYKQELHSKTVEIQKLFSEN-SDSNLKV--QRLSQLQPKFDNQEAIIKQKDLTIENLS 587

Query: 769  SELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLA 828
             +++K ++++   E  +  ++  + +L RK  +L + +Q        +TI+ D  ++   
Sbjct: 588  QQITKQQAQLHENENKLQQLQIDKETLNRKNVELSNQIQ------IHHTIKNDLQISS-- 639

Query: 829  VLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDL 888
                 D +   +L+  E  +  +  +       N N QI L   +         +N+ D 
Sbjct: 640  --NKEDPIQHIELMSSEQTSTSIFDQTF----SNINYQILLFTEENTTQIKSILSNKIDN 693

Query: 889  AESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNE 948
             E+   +   + + L+  +++  H  Q L  Q ++ +   E  +  + +     ++ L E
Sbjct: 694  LENNLLRTINKYQKLQEIIQKNYHNIQNLYEQSQQNLIQKENLYQIENQKQQMQRQTLLE 753

Query: 949  KYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKM--NLELIDK-------HVQKQQTQ 999
            +  +    ++QLE Q Q     ++NLN   ++  ++   L+ +D+        +   QT+
Sbjct: 754  EVHQQTILISQLENQQQILSLQLKNLNQQNQDQKQVITQLQQLDEKQKIDDLQMGSNQTK 813

Query: 1000 SPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLEN 1059
              +  ++ IN+   L    +Q  +  I +   +NN   S ++ +++   +L         
Sbjct: 814  LEELQQRTINQEADLKKASEQNTQLEIQVKD-LNNQVQSKLNTINELRQELDSLKNNQTG 872

Query: 1060 MEEE---MQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFE--MNIPKTEGMII 1114
             + +   +Q+  KQ+L+   +N  L    ++   +++E++   L  +  +N    +G+  
Sbjct: 873  SQFDSIKLQQQQKQILELISNNTNLNQQSQDAQLRLREMEALNLELQDRVNQLSKQGVSQ 932

Query: 1115 SSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTK 1174
              TI  +    N ++               ++ +   +E   LQ+     N + ++ Y K
Sbjct: 933  KETINQLQQQ-NQMEVKQNLTFLQQMDPLQKQIDHLTRENRKLQQS----NNDFEKAYGK 987

Query: 1175 IIQLETLNTELTGHDVVNQEQ--INQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRG 1232
                  L T  +   V NQ+Q  I +L+ ++ Q+  +    +       ++I    +Q+ 
Sbjct: 988  ------LPTYGSPRKVQNQDQNQIKKLEDEILQIQYKFQQEIQEKNIELNNIQKQYEQQL 1041

Query: 1233 FEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQ--LLDSVQSSTQEETNKIVTME 1290
             E+ EL    +++ E +     ++L+ Q        +    ++   S   EE  K+   +
Sbjct: 1042 EEVRELKLDEISKLEQNCVILSNQLKQQQVVNNELLQNNSQIERDNSQLSEEIEKLKKQQ 1101

Query: 1291 QVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXX 1350
            ++ S QN+   K++   N + KY ++   I  L+  I D+ +                  
Sbjct: 1102 KLQS-QNQESLKQQDQINHECKYIELNQTIGNLQIIINDQNLQLLNFKNHTL-------- 1152

Query: 1351 DLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLE 1410
            DL  + + + ++Q Q+++   EE  Q+K S+               D++ +++E     +
Sbjct: 1153 DLEEQIKHF-EVQIQNLIKEKEELCQIKDSNKSDETFTKNQQNEELDSQNQLME-----Q 1206

Query: 1411 LKDSE-IYQKTHEYTITLTQRNDEFENV---RQQLVEYEK-RIEDLTYEKESELAILRLK 1465
            LK+ + I  + ++  + L Q+  E   +   +QQ++E ++  I+ LT   ES     + +
Sbjct: 1207 LKNEQFILDQVNQDKLKLQQQQIEQGQLIHQQQQVIECQQVEIKRLTLI-ESGSVEQKKE 1265

Query: 1466 MHENANHYETMQKES--EIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQ 1523
              +N +  ++ Q E    +++ +   EL  K  +  + + ++ EL + L + +   NE++
Sbjct: 1266 SDQNISKLQSNQAEQLLPVQQEEFQVELKQKQKQIEAKDIEIHELKQKLYQNLQLNNELE 1325

Query: 1524 TALENQEIEIVTLNDEITNLQNMVRASSSKI 1554
              L++++   + L +EI  LQN+ +    KI
Sbjct: 1326 QQLKDKQAISIALENEIKQLQNVNQTQLQKI 1356



 Score =  116 bits (280), Expect = 4e-24
 Identities = 227/1152 (19%), Positives = 497/1152 (43%), Gaps = 116/1152 (10%)

Query: 493  IKDVNVKD--LIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNF-SK 549
            +K VN     LI+KL   ++ I  LN+EI+A+N+ +  +KS H + L Q Q  I++  S+
Sbjct: 10   LKQVNKNQTLLIQKL---QDDIELLNEEIEASNQQIDTLKSQHHISLSQQQSIIEDLRSE 66

Query: 550  VSDSNKEIVRLTEELHH--LSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMEN 607
              +  ++ + L  +     L  ++ + + +K N Q      +  + I+    K      +
Sbjct: 67   CQNYQQQNMELQSKFTQSVLQNQLLQSKYDKKNKQYKDQIVELKQQIKLSHLKNQDYQRD 126

Query: 608  LAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQ 667
            + E R K++   + +   L+    +L ++  +++  L D+ Q+  +    + +++ ++++
Sbjct: 127  ILELR-KSLDNNKLEICKLIDNSTLLNEQNKQLKANL-DLQQVDYENKIEQYQNL-IQDK 183

Query: 668  IDALSASKKELALVIENL-KLDK-----EQLYGTIKDLENDKEDIMNKLQNYIQENMDLT 721
             + ++    E  ++  NL +++K     E L+  I  L+   ++++ +L +    N  L 
Sbjct: 184  DEEITLIINENGVLNRNLEQMEKSANLSESLHSQIDTLQKQNQNLLIQLSDLQNHNTLLR 243

Query: 722  DKLEKMSAE-KISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICR 780
             +L+  S+E ++S    ++  +   + QTQ  ++  +Q+  + ++  +S++   +     
Sbjct: 244  QQLQLQSSEIQVSSSSLQLQLQSAPQQQTQDAMNRNVQQEMVVLQK-DSDIQALQQ--TT 300

Query: 781  LEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYT-IQEDELVNRLAVLMDHDRVVEK 839
              +++ + + + ++ + +     SY QE Q    +Y   Q + L  ++A L    +  E 
Sbjct: 301  EVQNVQLTQSQSFNNDLQL----SYQQETQNTEKDYNQNQINTLKQQIAKLTSDLKECEL 356

Query: 840  QLLEIEH-ENKELQKKN-QILLEENQNLQISLSDMQQHYNALVEKANRTDL-AESESTKY 896
            + ++++  +   + K N  + L E +N      D+  H N L+ +  + +L  + EST  
Sbjct: 357  KHVQVKQVQESTISKLNHDVRLLEQKN-----EDLILHNNKLINEIKQNELIQQKESTII 411

Query: 897  QTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEY 956
              ++ + E  L    H+ + L  +K+K+   +E + N Q++++ + +  L E   K   +
Sbjct: 412  CQKISEFEIQLLESHHQIEDLNQEKQKQERVVE-KLNLQMQASKQIQSKLEEDITKYQNF 470

Query: 957  VTQLEAQLQEYKNNIENLNMN------VEELNKMNLELIDKHVQKQQTQSPDYTEQYINE 1010
            +     QL+   +N  + + +       E+  ++N + +   + +Q        E Y  +
Sbjct: 471  LISHHKQLEAVTSNESSDSSDSSEETITEKPQQLNFDALCTKLTEQIRLVQLRLEIYEKQ 530

Query: 1011 INKLNALLKQKDEEIIAL--NQKINNAQVSYMSMV----SDYESKLAQFTTKLENMEEEM 1064
            I +    L  K  EI  L      +N +V  +S +     + E+ + Q    +EN+ +++
Sbjct: 531  IKQYKQELHSKTVEIQKLFSENSDSNLKVQRLSQLQPKFDNQEAIIKQKDLTIENLSQQI 590

Query: 1065 QRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKT--EGMIISST----- 1117
             +   QL +++   ++LQI     D +    K  +L+ ++ I  T    + ISS      
Sbjct: 591  TKQQAQLHENENKLQQLQI-----DKETLNRKNVELSNQIQIHHTIKNDLQISSNKEDPI 645

Query: 1118 --IEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTK- 1174
              IE MS +  +              + +  EE   Q +S+L  +   L   L     K 
Sbjct: 646  QHIELMSSEQTSTSIFDQTFSNINYQILLFTEENTTQIKSILSNKIDNLENNLLRTINKY 705

Query: 1175 -----IIQLETLNT----ELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSIS 1225
                 IIQ    N     E +  +++ +E + Q++++ +Q+  +   LL  V +    IS
Sbjct: 706  QKLQEIIQKNYHNIQNLYEQSQQNLIQKENLYQIENQKQQM--QRQTLLEEVHQQTILIS 763

Query: 1226 SAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNK 1285
               +Q+  +I  L  ++L Q+  D    + ++  QL   + K  Q +D +Q  + +    
Sbjct: 764  QLENQQ--QILSLQLKNLNQQNQD----QKQVITQLQQLDEK--QKIDDLQMGSNQ---- 811

Query: 1286 IVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXX 1345
                 ++  LQ +  ++E  L+   E+   +  Q++ L ++++ +               
Sbjct: 812  ----TKLEELQQRTINQEADLKKASEQNTQLEIQVKDLNNQVQSK---LNTINELRQELD 864

Query: 1346 XXXXXDLRTENQSYK-QMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLE 1404
                    ++  S K Q Q++ IL +   N  L + S            R+ + EA  LE
Sbjct: 865  SLKNNQTGSQFDSIKLQQQQKQILELISNNTNLNQQS-------QDAQLRLREMEALNLE 917

Query: 1405 LTHQL-ELKDSEIYQKTHEYTITLTQRNDEFE-----NVRQQLVEYEKRIEDLTYEKESE 1458
            L  ++ +L    + QK    TI   Q+ ++ E        QQ+   +K+I+ LT E    
Sbjct: 918  LQDRVNQLSKQGVSQKE---TINQLQQQNQMEVKQNLTFLQQMDPLQKQIDHLTRENRK- 973

Query: 1459 LAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAK 1518
               L+   ++    Y  +       +V+  ++  +K  E   L  Q  +  + ++E+  +
Sbjct: 974  ---LQQSNNDFEKAYGKLPTYGSPRKVQNQDQNQIKKLEDEILQIQY-KFQQEIQEKNIE 1029

Query: 1519 TNEMQTALENQEIEIVTLN-DEITNL-QNMVRASSSKIQKHVSFASDTKQGRDEQLDNTM 1576
             N +Q   E Q  E+  L  DEI+ L QN V  S+   Q+ V      +     + DN+ 
Sbjct: 1030 LNNIQKQYEQQLEEVRELKLDEISKLEQNCVILSNQLKQQQVVNNELLQNNSQIERDNSQ 1089

Query: 1577 NKELLDAVPRAE 1588
              E ++ + + +
Sbjct: 1090 LSEEIEKLKKQQ 1101



 Score =  113 bits (272), Expect = 4e-23
 Identities = 252/1274 (19%), Positives = 549/1274 (43%), Gaps = 127/1274 (9%)

Query: 388  QLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDT 447
            QLS +   Q+T+K  N+N+I  L+  I  L  DL + E    +                 
Sbjct: 318  QLSYQQETQNTEKDYNQNQINTLKQQIAKLTSDLKECELKHVQVKQVQESTISKLNHDVR 377

Query: 448  LIAQ----LQLEHQQ---HMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKD 500
            L+ Q    L L + +    ++   LI    +T    +I++ + QL  E + +I+D+N + 
Sbjct: 378  LLEQKNEDLILHNNKLINEIKQNELIQQKESTIICQKISEFEIQLL-ESHHQIEDLNQEK 436

Query: 501  -----LIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNK 555
                 ++EKL    +   Q+  +++           +H  +L+ +  T +  S  SDS++
Sbjct: 437  QKQERVVEKLNLQMQASKQIQSKLEEDITKYQNFLISHHKQLEAV--TSNESSDSSDSSE 494

Query: 556  EIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSG-RMIESDVYKKMIEMENLAETRLK 614
            E +    +  +      +L E+   +QL L  Y+   +  + +++ K +E++ L      
Sbjct: 495  ETITEKPQQLNFDALCTKLTEQIRLVQLRLEIYEKQIKQYKQELHSKTVEIQKLFS---- 550

Query: 615  AISLLESQKFDL-VQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSA 673
                 E+   +L VQ L  LQ K+D  E   A I Q        ++   +L +QI    A
Sbjct: 551  -----ENSDSNLKVQRLSQLQPKFDNQE---AIIKQ-------KDLTIENLSQQITKQQA 595

Query: 674  SKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKIS 733
               E    ++ L++DKE L     +L N  + I + ++N +Q + +  D ++ +      
Sbjct: 596  QLHENENKLQQLQIDKETLNRKNVELSNQIQ-IHHTIKNDLQISSNKEDPIQHIELMSSE 654

Query: 734  ELLAKINHEEQSKIQTQ---FGIDAKIQERDLY---IENIESELSKYKSRICRLEESIAV 787
            +    I  +  S I  Q   F  +   Q + +    I+N+E+ L +  ++  +L+E   +
Sbjct: 655  QTSTSIFDQTFSNINYQILLFTEENTTQIKSILSNKIDNLENNLLRTINKYQKLQE---I 711

Query: 788  MEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHE 847
            ++   ++++   +Q    L +K+  Y +   Q+ ++  +  +   H + +    LE + +
Sbjct: 712  IQKNYHNIQNLYEQSQQNLIQKENLY-QIENQKQQMQRQTLLEEVHQQTILISQLENQQQ 770

Query: 848  NKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAE-SESTKYQT-QLRDL-- 903
               LQ KN  L ++NQ+ +  ++ +QQ    L EK    DL   S  TK +  Q R +  
Sbjct: 771  ILSLQLKN--LNQQNQDQKQVITQLQQ----LDEKQKIDDLQMGSNQTKLEELQQRTINQ 824

Query: 904  ESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVT--QLE 961
            E++LK+ + ++  L +Q K     ++ + NT  E       + N +     + +   Q +
Sbjct: 825  EADLKKASEQNTQLEIQVKDLNNQVQSKLNTINELRQELDSLKNNQTGSQFDSIKLQQQQ 884

Query: 962  AQLQEYKNNIENLN-------MNVEELNKMNLELIDK--HVQKQ-----------QTQSP 1001
             Q+ E  +N  NLN       + + E+  +NLEL D+   + KQ           Q Q+ 
Sbjct: 885  KQILELISNNTNLNQQSQDAQLRLREMEALNLELQDRVNQLSKQGVSQKETINQLQQQNQ 944

Query: 1002 DYTEQYINEINKLNALLKQKDE---EIIALNQKINNAQVSYMSMVSDYESKLAQFT--TK 1056
               +Q +  + +++ L KQ D    E   L Q  N+ + +Y  + +    +  Q     +
Sbjct: 945  MEVKQNLTFLQQMDPLQKQIDHLTRENRKLQQSNNDFEKAYGKLPTYGSPRKVQNQDQNQ 1004

Query: 1057 LENMEEEMQRVS-KQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIIS 1115
            ++ +E+E+ ++  K   + ++ N EL  + ++ + Q++E++E KL  E++  +   +I+S
Sbjct: 1005 IKKLEDEILQIQYKFQQEIQEKNIELNNIQKQYEQQLEEVRELKLD-EISKLEQNCVILS 1063

Query: 1116 STIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQ---SAKLNTELQ-EC 1171
            + ++       N +             ++ EE E ++++  LQ Q   S K   ++  EC
Sbjct: 1064 NQLK--QQQVVNNELLQNNSQIERDNSQLSEEIEKLKKQQKLQSQNQESLKQQDQINHEC 1121

Query: 1172 -YTKIIQ--------LETLNTELTG---HDVVNQEQINQLKSKLEQLNTENDNLLSTVAE 1219
             Y ++ Q        +   N +L     H +  +EQI   + +++ L  E + L      
Sbjct: 1122 KYIELNQTIGNLQIIINDQNLQLLNFKNHTLDLEEQIKHFEVQIQNLIKEKEELCQIKDS 1181

Query: 1220 LRSSISSAVDQRGFEIA---ELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQ 1276
             +S  +   +Q+  E+    +L +Q   ++    Q  + +L++Q    E    QL+   Q
Sbjct: 1182 NKSDETFTKNQQNEELDSQNQLMEQLKNEQFILDQVNQDKLKLQQQQIEQG--QLIHQQQ 1239

Query: 1277 S--STQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQI--EILRSEIEDEKV 1332
                 Q+   K +T+ +  S++ K ++ ++++  LQ   A+ +  +  E  + E++ ++ 
Sbjct: 1240 QVIECQQVEIKRLTLIESGSVEQK-KESDQNISKLQSNQAEQLLPVQQEEFQVELKQKQK 1298

Query: 1333 AFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXX 1392
                              +L+  N+  +Q++++  ++I  EN ++K+             
Sbjct: 1299 QIEAKDIEIHELKQKLYQNLQLNNELEQQLKDKQAISIALEN-EIKQLQNVNQTQLQKIT 1357

Query: 1393 XRVNDAEAKVLELTHQLELKDSEIYQKTH-EYTITLTQRND-EFENVRQQLVEYEKRIED 1450
                D +    ++  Q +   ++  Q    E      Q+N  + +     L++  +++E 
Sbjct: 1358 ELNQDFQRSFEQVEEQKQTLTNQSEQNALLESKCNQMQQNVMKIQTQNNSLIQINQQLES 1417

Query: 1451 LTYEKESELAILRLKMHENANHYE----TMQKESEIERVKLIEELNVKITESVSLNKQVA 1506
             T E++  +    ++  E +   +     +Q E +  ++KL+++ N +  + +       
Sbjct: 1418 -TLEQQQHVNAQIIQKQEQSFQIQLDKLNIQLEDQQNQLKLLQQENGEYKQEIE-----K 1471

Query: 1507 ELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQ 1566
             +N   + E  K NE+    +  + +I  L D+I+  + +     ++I +  +      Q
Sbjct: 1472 IMNDQKQWEQNKLNELVQVKKESQGQIQKLMDQISRAEGLNVEHQNEILEMDNVIKKLIQ 1531

Query: 1567 GRDEQLDNTMNKEL 1580
             +D+ ++N M ++L
Sbjct: 1532 EKDKNINNDMIEQL 1545


>UniRef50_Q22NP6 Cluster: Putative uncharacterized protein; n=1;
            Tetrahymena thermophila SB210|Rep: Putative
            uncharacterized protein - Tetrahymena thermophila SB210
          Length = 1674

 Score =  134 bits (323), Expect = 3e-29
 Identities = 212/1067 (19%), Positives = 462/1067 (43%), Gaps = 94/1067 (8%)

Query: 334  LNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSET 393
            LN Q  Q N + ++     G + +   S SK  +      + +  +    +  +  SS  
Sbjct: 479  LNSQ-PQVNSQQKSNQTYSGQQKQLQQSLSKNNNTSNFFNNVQKNSINNNNHNNDNSSMW 537

Query: 394  LNQ--DTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQ 451
            LNQ  + D++I++NE       +Q      +DK   + EK+                + +
Sbjct: 538  LNQYENMDREIHQNEHQ-----LQQERDQFLDKIRDLEEKNKELRQFEKENIQLKQQLYE 592

Query: 452  LQLEHQQHMEGPSLIHVGTNT----EDVNEIAKVQEQLKQELNDEIKDV-NVKDLIEKLK 506
            +Q++ ++       +     T    +D N I ++Q  +++++  +IK   N++D+     
Sbjct: 593  IQIKSEEDKNHEVTMFKDDTTIFSQKDYN-IQRLQSLIQEDVESKIKTFSNIEDIKILCI 651

Query: 507  SAEEQITQLNDEID-AANKNMIKVKSNHKLKL----KQMQKTIDNFSKVSDSNKEIVRLT 561
              E +I QL   ID   N+   ++ S  +  +      +Q  +    + +  +KEI++  
Sbjct: 652  EKEIEIEQLKKRIDDLVNQQSSQILSGTQPDIVTQNADLQNELMQMKQNNQKSKEIIQQK 711

Query: 562  E-ELHHLSQKVA--ELEEEKGNLQLHLVDYDSG--RMIESDVYKKMIEMENLAETRLKAI 616
            + E+  L   +   +LE +K  LQ  +    S   R I   + +   E  N A T++   
Sbjct: 712  QLEIEQLKSVIQKQQLESQKA-LQTGISGMPSTERRSISYRMQESSRE-NNQANTQIYEQ 769

Query: 617  SLLESQKFDLVQELHILQQKYDE-VEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASK 675
             + E  K + + +LH  +++    V+++   I+ L+ + +  + +   LE +   ++   
Sbjct: 770  RIQE--KDNQIGQLHTKREELKTMVQERDNQINHLRKEYITVQGRLSKLESENFDINRKY 827

Query: 676  KELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISEL 735
            KEL  +I++  L+ E       + +   E+I  +LQ  +  N +    L +   + I+E 
Sbjct: 828  KELQSLIQSKTLECEDWKNKFIETDRKIENIP-QLQIELNRNQETIKDLNQRIEQLINE- 885

Query: 736  LAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSL 795
                N   + +I  +FG++ +I E++  IEN+ +++++ K +I   +  +  +++   S 
Sbjct: 886  ----NSGFKLRIGEKFGVENRINEKEREIENMITKINEQKKQIQEFQAKVVELQNIEKSK 941

Query: 796  ERKADQLGSYLQEKQKAYSEYTIQEDEL----------VNRLAVLMDHDRVVEKQLLEIE 845
            E    Q   + +E      +   Q D++          +  +++  + +  ++K++L+++
Sbjct: 942  EILFKQYKLFCEENNSLKQDIQSQLDKIQSLENQVQENIQDISLYQNENMQIKKEILQLK 1001

Query: 846  HENKELQKKNQILLEENQNLQISLSDMQQHYNAL-----------VEKANRTDLAESEST 894
             EN +LQ   Q  ++E ++LQ     + +  N L            E+A +      E+ 
Sbjct: 1002 LENSQLQASLQDAVQEKKDLQSENEKLNETVNQLKQNLSNTLSDTKERAQKVSYLTHENQ 1061

Query: 895  KYQTQLRDLESNLKRITHEHQTL---IVQKKKEIEDL-EI--EFNTQIESAIRDKKVLNE 948
                +L+  +  L+R+  E   +   I Q+K  +E+  EI  +F  +    I D K L  
Sbjct: 1062 NLANELKKNKQELERVRLEKNNILYEINQQKLSVENYNEIIKKFEDKESKQIEDMKQLER 1121

Query: 949  KYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQ----KQQTQSPDYT 1004
            +++K  + V QL   L E ++ ++N  + ++E N + LE + +  Q    + Q Q+  + 
Sbjct: 1122 EFDKKQKDVQQLNKLLSEQESRLQNQIIQIQEQN-IQLECLKQREQDLLNQIQQQNDQFA 1180

Query: 1005 EQYIN---EINK-----LNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTK 1056
             + IN   EIN+     LNA  ++ +++I   N+K          +   Y  ++ +    
Sbjct: 1181 IEGINLRMEINEKMSQMLNAEKEKFNQQINIANKKYEQKDDEINQLTQKYNQEITENDKL 1240

Query: 1057 LENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMI--I 1114
            ++ +EE  Q++++Q  +     ++L+ L +E   QI ++ +T    E N  K +  I  I
Sbjct: 1241 IKKVEEYQQKLNEQFREMTDTKQKLESLQKEYQQQIHKIIKTN---EQNQKKDQNKIEEI 1297

Query: 1115 SSTIEPMSDDANNVDXXXXXXXXXX----XXLKVQEEEEFIQERSVLQEQSAKLNTELQE 1170
            S  +     +   ++                 K   + + IQ+    Q Q   +  E ++
Sbjct: 1298 SEQLRAAIQEKETIEQRLKSKREDAQIWEEKYKKLLQAKEIQQYFDYQNQLTNIKEESEQ 1357

Query: 1171 CYTKIIQLETLNTELTGHDVVNQEQINQ-LKSKLEQLNTENDNLLSTVAELRSSISSAVD 1229
                I+       E   +++   E+ NQ L+ +L+++    +   S  +E    +   + 
Sbjct: 1358 YNQMILNAYQQQIEEKNNEIKCLEEENQSLQQQLQKMVLLQNETYSQQSEKCKKLQEEIS 1417

Query: 1230 QRGFEI--AELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIV 1287
            QR  +I    +    L + + D +  +++ ++Q S  E++ E L    Q S  E+ N+ +
Sbjct: 1418 QREIQIETQTIEINQLKKYKLDQESEKYQWQMQKSKIENQLEVL--QKQYSELEKFNQGL 1475

Query: 1288 T--MEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKV 1332
               ++Q  S   ++QD  E ++     +  +I Q+EI   +IE E++
Sbjct: 1476 NSLLQQRQSEFQQIQDDYERVKKENRDHQRIIKQMEI---QIESEQL 1519



 Score =  125 bits (302), Expect = 9e-27
 Identities = 218/1070 (20%), Positives = 451/1070 (42%), Gaps = 113/1070 (10%)

Query: 228  MEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXX 287
            M+ E    + +L ++ +    +I  LEE NK  E  +FE   E+ +L Q+L +       
Sbjct: 544  MDREIHQNEHQLQQERDQFLDKIRDLEEKNK--ELRQFE--KENIQLKQQLYEIQIKSEE 599

Query: 288  XXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELEN 347
                   + K       ++   I+   SL   ++    K    +E +  +I    KE+E 
Sbjct: 600  DKNHEVTMFKDDTTIFSQKDYNIQRLQSLIQEDVESKIKTFSNIEDI--KILCIEKEIE- 656

Query: 348  KLATMGTESKAVSSPSKKGSPLISRKSGR---NTASKMKSPWSQLSSETLNQDTDKKINK 404
                       +    K+   L++++S +    T   + +  + L +E +    + + +K
Sbjct: 657  -----------IEQLKKRIDDLVNQQSSQILSGTQPDIVTQNADLQNELMQMKQNNQKSK 705

Query: 405  NEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPS 464
              I + ++ I+ L K ++ K+ + S+K             + ++  ++Q   +++ +  +
Sbjct: 706  EIIQQKQLEIEQL-KSVIQKQQLESQKALQTGISGMPSTERRSISYRMQESSRENNQANT 764

Query: 465  LIHVGTNTEDVNEIAKV---QEQLK---QELNDEIKD-----VNVKDLIEKLKSAEEQIT 513
             I+     E  N+I ++   +E+LK   QE +++I       + V+  + KL+S    I 
Sbjct: 765  QIYEQRIQEKDNQIGQLHTKREELKTMVQERDNQINHLRKEYITVQGRLSKLESENFDIN 824

Query: 514  QLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAE 573
            +   E+ +  ++      + K K  +  + I+N  ++     E+ R  E +  L+Q++ +
Sbjct: 825  RKYKELQSLIQSKTLECEDWKNKFIETDRKIENIPQLQI---ELNRNQETIKDLNQRIEQ 881

Query: 574  LEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLA---ETRLKAIS-----LLESQKFD 625
            L  E    +L + +      +E+ + +K  E+EN+      + K I      ++E Q  +
Sbjct: 882  LINENSGFKLRIGEKFG---VENRINEKEREIENMITKINEQKKQIQEFQAKVVELQNIE 938

Query: 626  LVQELHILQQK-YDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALV--- 681
              +E+   Q K + E  + L    Q Q D++ S    V  +E I  +S  + E   +   
Sbjct: 939  KSKEILFKQYKLFCEENNSLKQDIQSQLDKIQSLENQV--QENIQDISLYQNENMQIKKE 996

Query: 682  IENLKLDKEQLYGTIKDLENDKEDI------MNKLQNYIQENMDLTDKLEKMSAEKISEL 735
            I  LKL+  QL  +++D   +K+D+      +N+  N +++N+  T    K  A+K+S L
Sbjct: 997  ILQLKLENSQLQASLQDAVQEKKDLQSENEKLNETVNQLKQNLSNTLSDTKERAQKVSYL 1056

Query: 736  ------LA---KINHEEQSKIQTQFG-IDAKIQERDLYIENIESELSKYKSRICRLEESI 785
                  LA   K N +E  +++ +   I  +I ++ L +EN    + K++ +  +  E +
Sbjct: 1057 THENQNLANELKKNKQELERVRLEKNNILYEINQQKLSVENYNEIIKKFEDKESKQIEDM 1116

Query: 786  AVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIE 845
              +E      ++   QL   L E++       IQ  E   +L  L   ++ +   L +I+
Sbjct: 1117 KQLEREFDKKQKDVQQLNKLLSEQESRLQNQIIQIQEQNIQLECLKQREQDL---LNQIQ 1173

Query: 846  HENKELQKKN-QILLEENQNLQISLSDMQQHYNALVEKANRT-----DLAESESTKYQTQ 899
             +N +   +   + +E N+ +   L+  ++ +N  +  AN+      D     + KY  +
Sbjct: 1174 QQNDQFAIEGINLRMEINEKMSQMLNAEKEKFNQQINIANKKYEQKDDEINQLTQKYNQE 1233

Query: 900  LRDLESNLKRITHEHQTL------IVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKN 953
            + + +  +K++    Q L      +   K+++E L+ E+  QI   I+  +   +K +  
Sbjct: 1234 ITENDKLIKKVEEYQQKLNEQFREMTDTKQKLESLQKEYQQQIHKIIKTNEQNQKKDQNK 1293

Query: 954  IEYVT-QLEAQLQEYKNNIENLNMNVEELN----KMNLELIDKHVQK------QQTQSPD 1002
            IE ++ QL A +QE +   + L    E+      K    L  K +Q+      Q T   +
Sbjct: 1294 IEEISEQLRAAIQEKETIEQRLKSKREDAQIWEEKYKKLLQAKEIQQYFDYQNQLTNIKE 1353

Query: 1003 YTEQYINEI-NKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENME 1061
             +EQY   I N     +++K+ EI  L ++  + Q     MV       +Q + K + ++
Sbjct: 1354 ESEQYNQMILNAYQQQIEEKNNEIKCLEEENQSLQQQLQKMVLLQNETYSQQSEKCKKLQ 1413

Query: 1062 EEMQR--------------VSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIP 1107
            EE+ +              + K  LD +    + Q+   + ++Q++ L++     E    
Sbjct: 1414 EEISQREIQIETQTIEINQLKKYKLDQESEKYQWQMQKSKIENQLEVLQKQYSELEKFNQ 1473

Query: 1108 KTEGMIIS--STIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLN 1165
                ++    S  + + DD   V             +++Q E E +Q +  LQ Q     
Sbjct: 1474 GLNSLLQQRQSEFQQIQDDYERVKKENRDHQRIIKQMEIQIESEQLQNKR-LQSQKKDDE 1532

Query: 1166 TELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLS 1215
               Q    ++  LE  +++     V + +QIN LK   +  N E  N LS
Sbjct: 1533 NIKQNLIERLKSLEEDSSQQNKRFVESLQQINGLKDSFKTKNNELTNFLS 1582



 Score =  121 bits (291), Expect = 2e-25
 Identities = 197/1097 (17%), Positives = 456/1097 (41%), Gaps = 74/1097 (6%)

Query: 453  QLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQI 512
            Q EHQ   E    +    + E+ N+  +  E+   +L  ++ ++ +K   +K      ++
Sbjct: 550  QNEHQLQQERDQFLDKIRDLEEKNKELRQFEKENIQLKQQLYEIQIKSEEDK----NHEV 605

Query: 513  TQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVA 572
            T   D+    ++    ++    L  + ++  I  FS + D     +    E+  L +++ 
Sbjct: 606  TMFKDDTTIFSQKDYNIQRLQSLIQEDVESKIKTFSNIEDIKILCIEKEIEIEQLKKRID 665

Query: 573  ELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHI 632
            +L  ++ +  L     D      +D+  ++++M+   +   K+  +++ ++ ++ Q   +
Sbjct: 666  DLVNQQSSQILSGTQPDIVTQ-NADLQNELMQMK---QNNQKSKEIIQQKQLEIEQLKSV 721

Query: 633  LQQKYDEVEDKL-ADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQ 691
            +Q++  E +  L   IS + S    +E +S+    Q  +   ++    +  + ++ +K+ 
Sbjct: 722  IQKQQLESQKALQTGISGMPS----TERRSISYRMQESSRENNQANTQIYEQRIQ-EKDN 776

Query: 692  LYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQF 751
              G    L   +E+    L+  +QE  +  + L K     +   L+K+  E        F
Sbjct: 777  QIG---QLHTKREE----LKTMVQERDNQINHLRKEYIT-VQGRLSKLESEN-------F 821

Query: 752  GIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQK 811
             I+ K +E    I++   E   +K++    +  I  +   +  L R  + +    Q  ++
Sbjct: 822  DINRKYKELQSLIQSKTLECEDWKNKFIETDRKIENIPQLQIELNRNQETIKDLNQRIEQ 881

Query: 812  AYSEYTIQEDELVNRLAV---LMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQIS 868
              +E +  +  +  +  V   + + +R +E  + +I  + K++Q+  Q  + E QN++ S
Sbjct: 882  LINENSGFKLRIGEKFGVENRINEKEREIENMITKINEQKKQIQEF-QAKVVELQNIEKS 940

Query: 869  LSDMQQHYNALVEKAN--RTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIE 926
               + + Y    E+ N  + D+ +S+  K Q+    ++ N++ I+  +Q   +Q KKEI 
Sbjct: 941  KEILFKQYKLFCEENNSLKQDI-QSQLDKIQSLENQVQENIQDISL-YQNENMQIKKEIL 998

Query: 927  DLEIEFNTQIESAIRD----KKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELN 982
             L++E N+Q++++++D    KK L  + EK  E V QL+  L    ++ +     V  L 
Sbjct: 999  QLKLE-NSQLQASLQDAVQEKKDLQSENEKLNETVNQLKQNLSNTLSDTKERAQKVSYLT 1057

Query: 983  KMNLELIDKHVQKQQTQSPDYTEQ--YINEINKLNALLKQKDEEIIALNQKINNAQVSYM 1040
              N  L ++  + +Q       E+   + EIN+    ++  +E I     K +       
Sbjct: 1058 HENQNLANELKKNKQELERVRLEKNNILYEINQQKLSVENYNEIIKKFEDKESKQIEDMK 1117

Query: 1041 SMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKL 1100
             +  +++ K        + + E+  R+  Q++  ++ N +L+ L + + D + ++++   
Sbjct: 1118 QLEREFDKKQKDVQQLNKLLSEQESRLQNQIIQIQEQNIQLECLKQREQDLLNQIQQQND 1177

Query: 1101 TFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQ 1160
             F +     EG+ +   I        N +             K +++++ I + +     
Sbjct: 1178 QFAI-----EGINLRMEINEKMSQMLNAEKEKFNQQINIANKKYEQKDDEINQLT----- 1227

Query: 1161 SAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAEL 1220
              K N E+ E    I ++E    +L         ++   K KLE L  E    +  + + 
Sbjct: 1228 -QKYNQEITENDKLIKKVEEYQQKLNEQF----REMTDTKQKLESLQKEYQQQIHKIIKT 1282

Query: 1221 RSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQ 1280
                      +  EI+E  +  + ++E   Q+ + + R     +E KY++LL +     +
Sbjct: 1283 NEQNQKKDQNKIEEISEQLRAAIQEKETIEQRLKSK-REDAQIWEEKYKKLLQA-----K 1336

Query: 1281 EETNKIVTMEQVTSLQNKLQDKEEHLRNL-QEKYADVINQIEILRSEIEDEKVAFXXXXX 1339
            E         Q+T+++ + +   + + N  Q++  +  N+I+ L  E +  +        
Sbjct: 1337 EIQQYFDYQNQLTNIKEESEQYNQMILNAYQQQIEEKNNEIKCLEEENQSLQQQLQKMVL 1396

Query: 1340 XXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAE 1399
                         +   +   Q + Q      E N QLKK              + +  E
Sbjct: 1397 LQNETYSQQSEKCKKLQEEISQREIQIETQTIEIN-QLKKYKLDQESEKYQWQMQKSKIE 1455

Query: 1400 AKVLELTHQ---LELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKE 1456
             ++  L  Q   LE  +  +     +      Q  D++E V+++  ++++ I+ +  + E
Sbjct: 1456 NQLEVLQKQYSELEKFNQGLNSLLQQRQSEFQQIQDDYERVKKENRDHQRIIKQMEIQIE 1515

Query: 1457 SELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEV 1516
            SE   L+ K  ++    +   K++ IER+K +EE + +  ++    + + ++N   +   
Sbjct: 1516 SEQ--LQNKRLQSQKKDDENIKQNLIERLKSLEEDSSQ--QNKRFVESLQQINGLKDSFK 1571

Query: 1517 AKTNEMQTALENQEIEI 1533
             K NE+   L     +I
Sbjct: 1572 TKNNELTNFLSKTNKQI 1588



 Score = 93.9 bits (223), Expect = 3e-17
 Identities = 171/913 (18%), Positives = 397/913 (43%), Gaps = 85/913 (9%)

Query: 685  LKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKIN-HEE 743
            L+ +++Q    I+DLE   ++    L+ + +EN+ L  +L ++  +   +   ++   ++
Sbjct: 555  LQQERDQFLDKIRDLEEKNKE----LRQFEKENIQLKQQLYEIQIKSEEDKNHEVTMFKD 610

Query: 744  QSKIQTQFGIDAKIQE-RDLYIENIESELSKYKS----RICRLEESIAVMEDRRYSLERK 798
             + I +Q   D  IQ  + L  E++ES++  + +    +I  +E+ I + E  +  ++  
Sbjct: 611  DTTIFSQK--DYNIQRLQSLIQEDVESKIKTFSNIEDIKILCIEKEIEI-EQLKKRIDDL 667

Query: 799  ADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDR----VVEKQLLEIEHENKELQKK 854
             +Q  S +    +   +   Q  +L N L  +  +++    +++++ LEIE     +QK+
Sbjct: 668  VNQQSSQILSGTQP--DIVTQNADLQNELMQMKQNNQKSKEIIQQKQLEIEQLKSVIQKQ 725

Query: 855  NQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTK---YQTQLRDLESNLKRI- 910
                LE  + LQ  +S M       +    +    E+       Y+ ++++ ++ + ++ 
Sbjct: 726  Q---LESQKALQTGISGMPSTERRSISYRMQESSRENNQANTQIYEQRIQEKDNQIGQLH 782

Query: 911  --THEHQTLIVQKKKEIEDLEIEFNT---QIESAIRDKKVLNEKYEKNIEYVTQLEAQLQ 965
                E +T++ ++  +I  L  E+ T   ++     +   +N KY++    +     + +
Sbjct: 783  TKREELKTMVQERDNQINHLRKEYITVQGRLSKLESENFDINRKYKELQSLIQSKTLECE 842

Query: 966  EYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEI 1025
            ++KN     +  +E + ++ +EL     Q+         EQ INE +     + +K    
Sbjct: 843  DWKNKFIETDRKIENIPQLQIEL--NRNQETIKDLNQRIEQLINENSGFKLRIGEKFGVE 900

Query: 1026 IALNQKINNAQVSYMSMVSDYESKLAQFTTK---LENMEEEMQRVSKQLLDSKQHNEELQ 1082
              +N+K    + + ++ +++ + ++ +F  K   L+N+E+  + + KQ     + N  L+
Sbjct: 901  NRINEKEREIE-NMITKINEQKKQIQEFQAKVVELQNIEKSKEILFKQYKLFCEENNSLK 959

Query: 1083 ILVREQDDQIKELKET--KLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXX 1140
              ++ Q D+I+ L+    +   ++++ + E M I   I  +  + + +            
Sbjct: 960  QDIQSQLDKIQSLENQVQENIQDISLYQNENMQIKKEILQLKLENSQLQASLQDA----- 1014

Query: 1141 XLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLK 1200
               VQE+++   E   L E   +L   L    +   +     + LT  +     ++ + K
Sbjct: 1015 ---VQEKKDLQSENEKLNETVNQLKQNLSNTLSDTKERAQKVSYLTHENQNLANELKKNK 1071

Query: 1201 SKLEQLNTENDNLLSTVAELRSSISSAVDQ-RGFEIAELWK-QHLAQREADFQKTEHELR 1258
             +LE++  E +N+L  + + + S+ +  +  + FE  E  + + + Q E +F K + +++
Sbjct: 1072 QELERVRLEKNNILYEINQQKLSVENYNEIIKKFEDKESKQIEDMKQLEREFDKKQKDVQ 1131

Query: 1259 VQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVIN 1318
             QL+   S+ E  L +     QE+        Q+  L+ + QD    ++   +++A  I 
Sbjct: 1132 -QLNKLLSEQESRLQNQIIQIQEQNI------QLECLKQREQDLLNQIQQQNDQFA--IE 1182

Query: 1319 QIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLK 1378
             I  LR EI +EK++                  +   N+ Y+Q  ++ I  + ++  Q  
Sbjct: 1183 GIN-LRMEI-NEKMS-----QMLNAEKEKFNQQINIANKKYEQKDDE-INQLTQKYNQEI 1234

Query: 1379 KSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVR 1438
              +            ++N+   ++ +   +LE    E  Q+ H+   T  Q   + +N  
Sbjct: 1235 TENDKLIKKVEEYQQKLNEQFREMTDTKQKLESLQKEYQQQIHKIIKTNEQNQKKDQN-- 1292

Query: 1439 QQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITES 1498
             ++ E  +++     EKE+    L+ K  E+A  +E   K       KL++   ++  + 
Sbjct: 1293 -KIEEISEQLRAAIQEKETIEQRLKSK-REDAQIWEEKYK-------KLLQAKEIQ--QY 1341

Query: 1499 VSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHV 1558
                 Q+  +    +EE  + N+M      Q+IE    N+EI  L+   ++   ++QK V
Sbjct: 1342 FDYQNQLTNI----KEESEQYNQMILNAYQQQIE--EKNNEIKCLEEENQSLQQQLQKMV 1395

Query: 1559 SFASDTKQGRDEQ 1571
               ++T   + E+
Sbjct: 1396 LLQNETYSQQSEK 1408



 Score = 91.5 bits (217), Expect = 2e-16
 Identities = 144/747 (19%), Positives = 308/747 (41%), Gaps = 76/747 (10%)

Query: 839  KQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQT 898
            + LL  + +    QK NQ    + + LQ SLS      N        +    + +    +
Sbjct: 476  QSLLNSQPQVNSQQKSNQTYSGQQKQLQQSLSKNNNTSNFFNNVQKNSINNNNHNNDNSS 535

Query: 899  QLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVT 958
               +   N+ R  H+++  + Q++ +  D       +I       K L +  ++NI+   
Sbjct: 536  MWLNQYENMDREIHQNEHQLQQERDQFLD-------KIRDLEEKNKELRQFEKENIQLKQ 588

Query: 959  QL-EAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYI---NEINKL 1014
            QL E Q++  ++    + M  ++    + +  D ++Q+ Q+   +  E  I   + I  +
Sbjct: 589  QLYEIQIKSEEDKNHEVTMFKDDTTIFSQK--DYNIQRLQSLIQEDVESKIKTFSNIEDI 646

Query: 1015 NALLKQKDEEIIALNQKINNAQVSYMSMV-----SDYESKLAQFTTKLENMEEEMQRVSK 1069
              L  +K+ EI  L ++I++      S +      D  ++ A    +L  M++  Q+ SK
Sbjct: 647  KILCIEKEIEIEQLKKRIDDLVNQQSSQILSGTQPDIVTQNADLQNELMQMKQNNQK-SK 705

Query: 1070 QLLDSKQHN-EELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNV 1128
            +++  KQ   E+L+ ++++Q  + ++  +T ++    +P TE   IS  ++  S + N  
Sbjct: 706  EIIQQKQLEIEQLKSVIQKQQLESQKALQTGIS---GMPSTERRSISYRMQESSRENNQA 762

Query: 1129 DXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGH 1188
            +               Q  E+ IQE+     Q  +L+T+ +E  T + + +     L   
Sbjct: 763  NT--------------QIYEQRIQEKD---NQIGQLHTKREELKTMVQERDNQINHL--- 802

Query: 1189 DVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREA 1248
                +E I  ++ +L +L +EN ++     EL+S I S   +      E WK    + + 
Sbjct: 803  ---RKEYIT-VQGRLSKLESENFDINRKYKELQSLIQSKTLE-----CEDWKNKFIETDR 853

Query: 1249 DFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRN 1308
              +    +L+++L+  +   + L   ++    E +   + + +   ++N++ +KE  + N
Sbjct: 854  KIENIP-QLQIELNRNQETIKDLNQRIEQLINENSGFKLRIGEKFGVENRINEKEREIEN 912

Query: 1309 LQEKYADVINQIEILRSE------IEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQM 1362
            +  K  +   QI+  +++      IE  K                   D++++    + +
Sbjct: 913  MITKINEQKKQIQEFQAKVVELQNIEKSKEILFKQYKLFCEENNSLKQDIQSQLDKIQSL 972

Query: 1363 QEQSILNINE------ENAQLKKSSXXXXXXXXXXXXRVNDA----------EAKVLELT 1406
            + Q   NI +      EN Q+KK               + DA            K+ E  
Sbjct: 973  ENQVQENIQDISLYQNENMQIKKEILQLKLENSQLQASLQDAVQEKKDLQSENEKLNETV 1032

Query: 1407 HQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKM 1466
            +QL+   S     T E    ++    E +N+  +L + ++ +E +  EK + L  +  + 
Sbjct: 1033 NQLKQNLSNTLSDTKERAQKVSYLTHENQNLANELKKNKQELERVRLEKNNILYEINQQK 1092

Query: 1467 HENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTAL 1526
                N+ E ++K  + E  K IE++     E     K V +LNK L E+ ++       +
Sbjct: 1093 LSVENYNEIIKKFEDKES-KQIEDMKQLEREFDKKQKDVQQLNKLLSEQESRLQNQIIQI 1151

Query: 1527 ENQEIEIVTLNDEITNLQNMVRASSSK 1553
            + Q I++  L     +L N ++  + +
Sbjct: 1152 QEQNIQLECLKQREQDLLNQIQQQNDQ 1178



 Score = 83.4 bits (197), Expect = 5e-14
 Identities = 165/861 (19%), Positives = 360/861 (41%), Gaps = 77/861 (8%)

Query: 151  IKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXX 210
            I+EKDN +  L  K +       +L+  + E+D  I    K                   
Sbjct: 771  IQEKDNQIGQLHTKRE-------ELKTMVQERDNQINHLRKEYITVQGRLSKLESENFDI 823

Query: 211  XEDTKQQMTKMQENFIAMEAEWKD---EKQRLLKDIESKDVRISSLEEANKLLEAARFEI 267
                K+  + +Q   +  E +WK+   E  R +++I    + ++  +E  K L     ++
Sbjct: 824  NRKYKELQSLIQSKTLECE-DWKNKFIETDRKIENIPQLQIELNRNQETIKDLNQRIEQL 882

Query: 268  SLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKK 327
              E+S     + +              + +  I    E+K +I+E    ++  +  + K 
Sbjct: 883  INENSGFKLRIGEKFGVENRINEKEREI-ENMITKINEQKKQIQE-FQAKVVELQNIEKS 940

Query: 328  IELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASK-----M 382
             E+L        + N  L+  + +   + +++ +  ++    IS     N   K     +
Sbjct: 941  KEILFKQYKLFCEENNSLKQDIQSQLDKIQSLENQVQENIQDISLYQNENMQIKKEILQL 1000

Query: 383  KSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXX 442
            K   SQL +   +   +KK  ++E  KL   +  L ++L +    +S+            
Sbjct: 1001 KLENSQLQASLQDAVQEKKDLQSENEKLNETVNQLKQNLSN---TLSDTKERAQKVSYLT 1057

Query: 443  XGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKV-QEQLKQELNDEIKDVNVKDL 501
                 L  +L+ +++Q +E   L       E  N + ++ Q++L  E  +EI    +K  
Sbjct: 1058 HENQNLANELK-KNKQELERVRL-------EKNNILYEINQQKLSVENYNEI----IKKF 1105

Query: 502  IEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLT 561
             +K     E + QL  E D   K+   V+  +KL  +Q  +  +   ++ + N ++  L 
Sbjct: 1106 EDKESKQIEDMKQLEREFDKKQKD---VQQLNKLLSEQESRLQNQIIQIQEQNIQLECLK 1162

Query: 562  EELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLES 621
            +    L  ++     ++ N Q  +     G  +  ++ +KM +M N            E 
Sbjct: 1163 QREQDLLNQI-----QQQNDQFAI----EGINLRMEINEKMSQMLN-----------AEK 1202

Query: 622  QKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSV-HLEEQIDALSASKKELAL 680
            +KF+  Q+++I  +KY++ +D++  ++Q  + ++    K +  +EE    L+   +E+  
Sbjct: 1203 EKFN--QQINIANKKYEQKDDEINQLTQKYNQEITENDKLIKKVEEYQQKLNEQFREMTD 1260

Query: 681  VIENLK-LDKE---QLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAE-KISEL 735
              + L+ L KE   Q++  IK  E +++   NK++   ++      + E +    K    
Sbjct: 1261 TKQKLESLQKEYQQQIHKIIKTNEQNQKKDQNKIEEISEQLRAAIQEKETIEQRLKSKRE 1320

Query: 736  LAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICR-LEESIAVMEDRRYS 794
             A+I  E+  K+     I      ++  + NI+ E  +Y   I    ++ I    +    
Sbjct: 1321 DAQIWEEKYKKLLQAKEIQQYFDYQN-QLTNIKEESEQYNQMILNAYQQQIEEKNNEIKC 1379

Query: 795  LERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRV-VEKQLLEIEHENK-ELQ 852
            LE +   L   LQ+     +E   Q+ E   +L   +    + +E Q +EI    K +L 
Sbjct: 1380 LEEENQSLQQQLQKMVLLQNETYSQQSEKCKKLQEEISQREIQIETQTIEINQLKKYKLD 1439

Query: 853  KKNQILLEENQNLQI--SLSDMQQHYNALVEKANR--TDLAESESTKYQTQLRDLESNLK 908
            ++++    + Q  +I   L  +Q+ Y+ L EK N+    L +   +++Q Q++D    +K
Sbjct: 1440 QESEKYQWQMQKSKIENQLEVLQKQYSEL-EKFNQGLNSLLQQRQSEFQ-QIQDDYERVK 1497

Query: 909  RITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQL-QEY 967
            +   +HQ +I Q + +IE  +++ N +++S  +D + + +   + ++ + +  +Q  + +
Sbjct: 1498 KENRDHQRIIKQMEIQIESEQLQ-NKRLQSQKKDDENIKQNLIERLKSLEEDSSQQNKRF 1556

Query: 968  KNNIENLNMNVEELNKMNLEL 988
              +++ +N   +     N EL
Sbjct: 1557 VESLQQINGLKDSFKTKNNEL 1577



 Score = 48.4 bits (110), Expect = 0.002
 Identities = 107/580 (18%), Positives = 233/580 (40%), Gaps = 62/580 (10%)

Query: 215  KQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKL 274
            K+ +    E       + K      L D + +  ++S L   N+        ++ E  K 
Sbjct: 1018 KKDLQSENEKLNETVNQLKQNLSNTLSDTKERAQKVSYLTHENQ-------NLANELKKN 1070

Query: 275  AQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELT----KKIEL 330
             QELE+                K S+E   E   + E+K S +I +M +L     KK + 
Sbjct: 1071 KQELERVRLEKNNILYEINQ-QKLSVENYNEIIKKFEDKESKQIEDMKQLEREFDKKQKD 1129

Query: 331  LEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNT-----ASKMKSP 385
            ++ LN  + +    L+N++  +  ++  +    ++   L+++   +N         ++  
Sbjct: 1130 VQQLNKLLSEQESRLQNQIIQIQEQNIQLECLKQREQDLLNQIQQQNDQFAIEGINLRME 1189

Query: 386  WSQLSSETLNQDTDKKINKNEIA---------KLEMVIQSLNKDLVDKEYVISE-KDTXX 435
             ++  S+ LN + +K   +  IA         ++  + Q  N+++ + + +I + ++   
Sbjct: 1190 INEKMSQMLNAEKEKFNQQINIANKKYEQKDDEINQLTQKYNQEITENDKLIKKVEEYQQ 1249

Query: 436  XXXXXXXXGKDTL--IAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLK------- 486
                      DT   +  LQ E+QQ +      +     +D N+I ++ EQL+       
Sbjct: 1250 KLNEQFREMTDTKQKLESLQKEYQQQIHKIIKTNEQNQKKDQNKIEEISEQLRAAIQEKE 1309

Query: 487  ---QELNDEIKDVNV-KDLIEKLKSAEE---------QITQLNDEIDAANKNMIKVKSNH 533
               Q L  + +D  + ++  +KL  A+E         Q+T + +E +  N+ ++      
Sbjct: 1310 TIEQRLKSKREDAQIWEEKYKKLLQAKEIQQYFDYQNQLTNIKEESEQYNQMILNAYQQQ 1369

Query: 534  KLKLKQMQKTID--NFSKVSDSNKEIVRLTEELHHLSQKVAELEEE--KGNLQLHLVDYD 589
              +     K ++  N S      K ++   E     S+K  +L+EE  +  +Q+     +
Sbjct: 1370 IEEKNNEIKCLEEENQSLQQQLQKMVLLQNETYSQQSEKCKKLQEEISQREIQIETQTIE 1429

Query: 590  SGRMI------ESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELH-ILQQKYDEVED 642
              ++       ES+ Y+  ++   + E +L+ +    S+     Q L+ +LQQ+  E + 
Sbjct: 1430 INQLKKYKLDQESEKYQWQMQKSKI-ENQLEVLQKQYSELEKFNQGLNSLLQQRQSEFQQ 1488

Query: 643  KLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLEND 702
               D  +++ +    +     +E QI++     K L    ++ +  K+ L   +K LE D
Sbjct: 1489 IQDDYERVKKENRDHQRIIKQMEIQIESEQLQNKRLQSQKKDDENIKQNLIERLKSLEED 1548

Query: 703  KEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHE 742
                  +    +Q+   L D   K    +++  L+K N +
Sbjct: 1549 SSQQNKRFVESLQQINGLKDSF-KTKNNELTNFLSKTNKQ 1587



 Score = 45.2 bits (102), Expect = 0.015
 Identities = 75/381 (19%), Positives = 161/381 (42%), Gaps = 18/381 (4%)

Query: 176  QEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDE 235
            ++K +E +Q+ +  N+  T                 E  ++ MT  ++   +++ E++ +
Sbjct: 1217 EQKDDEINQLTQKYNQEITENDKLIKKVEEYQQKLNEQFRE-MTDTKQKLESLQKEYQQQ 1275

Query: 236  KQRLLKDIESKDVRISS-LEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXX 294
              +++K  E    +  + +EE ++ L AA  E      +L  + E               
Sbjct: 1276 IHKIIKTNEQNQKKDQNKIEEISEQLRAAIQEKETIEQRLKSKREDAQIWEEKYKKLLQA 1335

Query: 295  LAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIR---QTNKELENKLAT 351
               Q       + T I+E+   E  N   L    + +E  N +I+   + N+ L+ +L  
Sbjct: 1336 KEIQQYFDYQNQLTNIKEES--EQYNQMILNAYQQQIEEKNNEIKCLEEENQSLQQQLQK 1393

Query: 352  MGT-ESKAVSSPSKKGSPLISRKSGRNTASKMKS-PWSQLSSETLNQDTDKKINKNEIAK 409
            M   +++  S  S+K   L    S R    + ++   +QL    L+Q+++K   + + +K
Sbjct: 1394 MVLLQNETYSQQSEKCKKLQEEISQREIQIETQTIEINQLKKYKLDQESEKYQWQMQKSK 1453

Query: 410  LEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVG 469
            +E  ++ L K     +Y  SE +            + +   Q+Q ++++ ++  +  H  
Sbjct: 1454 IENQLEVLQK-----QY--SELEKFNQGLNSLLQQRQSEFQQIQDDYER-VKKENRDHQR 1505

Query: 470  TNTEDVNEIAKVQEQLKQELNDEIKDVNVK-DLIEKLKSAEEQITQLNDEIDAANKNMIK 528
               +   +I   Q Q K+  + +  D N+K +LIE+LKS EE  +Q N     + + +  
Sbjct: 1506 IIKQMEIQIESEQLQNKRLQSQKKDDENIKQNLIERLKSLEEDSSQQNKRFVESLQQING 1565

Query: 529  VKSNHKLKLKQMQKTIDNFSK 549
            +K + K K  ++   +   +K
Sbjct: 1566 LKDSFKTKNNELTNFLSKTNK 1586


>UniRef50_A0CUE6 Cluster: Chromosome undetermined scaffold_28, whole
            genome shotgun sequence; n=1; Paramecium tetraurelia|Rep:
            Chromosome undetermined scaffold_28, whole genome shotgun
            sequence - Paramecium tetraurelia
          Length = 1479

 Score =  134 bits (323), Expect = 3e-29
 Identities = 239/1252 (19%), Positives = 552/1252 (44%), Gaps = 129/1252 (10%)

Query: 445  KDTLIAQL-QLEHQQHMEGPSLIHVGTNTEDVNEIAKVQ-EQLKQE------LNDEIKDV 496
            K+TL + L +L++ ++ +   L+ + +  + + E    Q   LK+E      LN+ + ++
Sbjct: 99   KNTLESNLNELKYHENAQKLELLELESKCQILQEETSTQTNNLKEENIRLQGLNETL-EI 157

Query: 497  NVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSD--SN 554
             +KD   +     +QI Q+N++ +  N+   + + N  L  + + +  +   ++ +  S 
Sbjct: 158  QIKDQKSQNIDQLKQIEQINEKYNLINEQFTQQQKNLSLFEQTINEQRNQIQEIDNGQSK 217

Query: 555  KEIVRLT---EELHHL-SQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAE 610
            +E+  L    E+L  L +Q + E E++   +           MIE+   K +    +  E
Sbjct: 218  QELNILAIQHEQLKLLHNQLIIEKEQQLSYINKQCQQEIDVLMIEN---KDLSFQNHKLE 274

Query: 611  TRLKAISLLESQKFD------LVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSV-H 663
             ++K + L+ +Q  D       +QE  + Q  + E +  L     ++ ++    I+S+  
Sbjct: 275  QKIKKLQLINNQLIDQQDINLKIQENELKQLYFGEQQKNLE--LDIKINETYQRIESLQQ 332

Query: 664  LEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKL----QNYIQENMD 719
            L EQ++      ++   V E   +D  ++   +    N +E  + KL    +  +Q+  D
Sbjct: 333  LNEQLEQKIKDLEQQLNVQEQQNVDLHKVNNELVQNNNIQESNLQKLKIINEIQLQKITD 392

Query: 720  LTDKLEKMSAEKISELLA--KINHEEQSKIQ-TQFGIDAKIQERDLYIENIESEL-SKYK 775
            L +  ++++ +K+++ ++  K+  ++  K++ T   +  K++++ +  +++ S+L +KY 
Sbjct: 393  LANG-QELNLQKLNDPISQLKLLPQKFQKLEITLLRLLPKLRQKIIQQQDLISQLINKYS 451

Query: 776  SRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDR 835
            + I  L + +   +D+   L  +  Q      E +    +   ++ + +++L   +D + 
Sbjct: 452  NNIDDLNQQLLKQQDKSNQLYDQVLQNQELNSELKNLNDKLESEKQQNISKLEKQIDLNE 511

Query: 836  VVEKQLLEIEHENKELQKKNQILLEENQNLQISL-SDMQQHYNALVEKANRTDLAESEST 894
             +  Q   +  + +E + + + L ++ Q+ Q    S++QQ         N  ++   E T
Sbjct: 512  QIGAQNAFLSQQKQEFENELKQLQQDYQDQQSKWNSEIQQKIQENSTIKNENEIFNQELT 571

Query: 895  KYQTQLRDLESNLKRI----THEHQTLIVQKKKEIEDLEIEFNTQ------IESAIRDKK 944
            K   Q++ L   +K+       E + LI+++++EI+ +E++ + Q       ++  ++K+
Sbjct: 572  KKNEQIQILSKEIKQFQINSQCEQEELILKRQQEIKIIEVKISEQQNNFLNNQNQYQEKQ 631

Query: 945  VL-----NEKYEKNIEYVTQLEAQL----QEYKNNIENLNMNVEELNKMNLELIDKHVQK 995
            +L       K+ K  E    L  +L     E K  I+   +    LN+ N +++  +++ 
Sbjct: 632  ILRLNFIKNKFNKEQEVTKLLNIELNSIQMEMKQLIDRHLVQSSSLNQEN-QILQDNLKI 690

Query: 996  QQTQSPDYTEQYI---NEINKLNALLKQKDEEIIA---LNQKINNAQV----SYMSMVSD 1045
            ++    D   Q +    +I KLN  + QKD+EI +   +N  +N  Q+    +  + ++ 
Sbjct: 691  EREAKEDLNSQIVQIKKQIVKLNNTINQKDQEIESFRKINDALNERQIIDKQALSNDLNS 750

Query: 1046 YESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKEL----KETKL- 1100
             +   +QF  +++ +++++  +++ LL   Q   E+Q L ++  DQ+KE+    +E ++ 
Sbjct: 751  IQESNSQFKQQIQQLQDQINNINEILLAKDQ---EIQTLKQKLQDQVKEINLKTQEYEIK 807

Query: 1101 TFEMNIPKTEGM-IISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQE 1159
              E+N  K EG+  +    + +    +N++            L+ Q  E+        +E
Sbjct: 808  NVELNNIKEEGLKKLKCKDDEILQLQDNLEQQKIKYESQSLVLQ-QNLEQLQINLKKKEE 866

Query: 1160 QSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLL----S 1215
            + +++N+  +E      +L+  N  L G  +  ++ +N     +E +  + D+ +    +
Sbjct: 867  EISRINSANEELKASNKELQDQNKILQGQSLQQEQNLNLRIVNIEAIIEDKDDEIQLKQN 926

Query: 1216 TVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSV 1275
             + +L+ SI++ +++   +   + KQ    R    Q    EL+ Q      ++E+L    
Sbjct: 927  ELNDLKESINTYLERFSCDQQIIQKQQFEIR--ILQNQIEELKNQ-----GEFEKLEFQQ 979

Query: 1276 QSSTQEETNKIVTME-QVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAF 1334
            Q   +++ + I   E ++TSL N +++KE+    L++   DVI   +  +S+  ++   F
Sbjct: 980  QLQIKKQKSNIGQFEDEITSLNNVIEEKEKPTDQLKQNMNDVITN-KFNQSQYVNQIKEF 1038

Query: 1335 --XXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILN--------INEENAQLKKSSXXX 1384
                              D+++  Q +    +Q ++N        + EEN  ++K     
Sbjct: 1039 DDFDENNKNSVNEQQQLIDIKSARQRWINETDQELVNEERVLFQKLREENNIIRKQLADQ 1098

Query: 1385 XXXXXXXXXRVNDAEAKVLELTHQLELK-----------------DSEIYQKTHEYTITL 1427
                     R+ D E  +L L  +LE +                 + +I Q + +  I  
Sbjct: 1099 EKELIINNQRIYDHEETILNLQQELEARKYNNNSPRPLDKEINQDEGQIDQDSEQQQIQQ 1158

Query: 1428 TQRNDEFENVR-QQLVEYEKRIEDL---TYEKESELAILRLKMHENANHYETMQKESEIE 1483
             Q   +  NV+ QQ+++  +  E L    Y+ + EL +   K++++    + +Q E   +
Sbjct: 1159 KQYQQKVSNVQPQQILKLREENEILKRNLYDLQLELELNNQKLNDHEQTIQNLQTELYEK 1218

Query: 1484 RVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNL 1543
            + K     N  +   VS   Q++  +K  +E++         +E+Q+   V  ND     
Sbjct: 1219 KEKTENFENKLMDNQVS---QLSNRSKLSQEQIRFDQLPDIGVEDQD---VADNDSFEQE 1272

Query: 1544 QNMVRASSSKI-QKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDLAMY 1594
            +N+ +     + Q+ ++      Q   +QL    NK L D + R      +Y
Sbjct: 1273 ENIFQQRQLNLKQQELTNTIKELQEEIKQL-KEQNKSLQDFINRGSAPSPIY 1323



 Score =  133 bits (321), Expect = 4e-29
 Identities = 255/1212 (21%), Positives = 512/1212 (42%), Gaps = 134/1212 (11%)

Query: 458  QHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQL-- 515
            QH E   L+H     E   +++ + +Q +QE+  ++  +  KDL  +    E++I +L  
Sbjct: 226  QH-EQLKLLHNQLIIEKEQQLSYINKQCQQEI--DVLMIENKDLSFQNHKLEQKIKKLQL 282

Query: 516  --NDEIDAANKNMIKVKSNH--KLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKV 571
              N  ID  + N+ K++ N   +L   + QK ++   K++++ + I  L +    L QK+
Sbjct: 283  INNQLIDQQDINL-KIQENELKQLYFGEQQKNLELDIKINETYQRIESLQQLNEQLEQKI 341

Query: 572  AELEE-----EKGNLQLHLVDYD---SGRMIESDVYKKMI--EMENLAETRLKAISLLES 621
             +LE+     E+ N+ LH V+ +   +  + ES++ K  I  E++    T L     L  
Sbjct: 342  KDLEQQLNVQEQQNVDLHKVNNELVQNNNIQESNLQKLKIINEIQLQKITDLANGQELNL 401

Query: 622  QKF-DLVQELHILQQKYDEVEDKLADISQ------LQSDQVCSEIKSVH------LEEQI 668
            QK  D + +L +L QK+ ++E  L  +        +Q   + S++ + +      L +Q+
Sbjct: 402  QKLNDPISQLKLLPQKFQKLEITLLRLLPKLRQKIIQQQDLISQLINKYSNNIDDLNQQL 461

Query: 669  DALSASKKELA-LVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKM 727
                    +L   V++N +L+ E L      LE++K+  ++KL+  I  N  +  +   +
Sbjct: 462  LKQQDKSNQLYDQVLQNQELNSE-LKNLNDKLESEKQQNISKLEKQIDLNEQIGAQNAFL 520

Query: 728  SAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAV 787
            S +K  E   ++   +Q     Q   +++IQ++      I++E   +   + +  E I +
Sbjct: 521  SQQK-QEFENELKQLQQDYQDQQSKWNSEIQQKIQENSTIKNENEIFNQELTKKNEQIQI 579

Query: 788  M--EDRRYSLERKADQLGSYLQEKQKA-YSEYTIQEDELVNRLAVLMDHDRVVEKQLLEI 844
            +  E +++ +  + +Q    L+ +Q+    E  I E +  N    L + ++  EKQ+L +
Sbjct: 580  LSKEIKQFQINSQCEQEELILKRQQEIKIIEVKISEQQ--NNF--LNNQNQYQEKQILRL 635

Query: 845  EHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLE 904
                 +  K+ ++     + L I L+ +Q     L+++     L +S S   + Q+  L+
Sbjct: 636  NFIKNKFNKEQEV----TKLLNIELNSIQMEMKQLIDR----HLVQSSSLNQENQI--LQ 685

Query: 905  SNLKRITHEHQTL---IVQKKKEI---------EDLEIEFNTQIESAIRDKKV------- 945
             NLK      + L   IVQ KK+I         +D EIE   +I  A+ ++++       
Sbjct: 686  DNLKIEREAKEDLNSQIVQIKKQIVKLNNTINQKDQEIESFRKINDALNERQIIDKQALS 745

Query: 946  --LNEKYEKNIEYVTQLEAQLQEYKNNI-ENLNMNVEELNKMNLELIDKHVQ-KQQTQSP 1001
              LN   E N ++  Q++ QLQ+  NNI E L    +E+  +  +L D+  +   +TQ  
Sbjct: 746  NDLNSIQESNSQFKQQIQ-QLQDQINNINEILLAKDQEIQTLKQKLQDQVKEINLKTQEY 804

Query: 1002 DYTEQYINEINKLNAL-LKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENM 1060
            +     +N I +     LK KD+EI+ L   +   ++ Y S     +  L Q    L+  
Sbjct: 805  EIKNVELNNIKEEGLKKLKCKDDEILQLQDNLEQQKIKYESQSLVLQQNLEQLQINLKKK 864

Query: 1061 EEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEP 1120
            EEE+ R++         NEEL+   +E  DQ K L+   L  E N+     + I + IE 
Sbjct: 865  EEEISRINSA-------NEELKASNKELQDQNKILQGQSLQQEQNL-NLRIVNIEAIIED 916

Query: 1121 MSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAK---LNTELQECYTKIIQ 1177
              D+   +             +     E F  ++ ++Q+Q  +   L  +++E   +  +
Sbjct: 917  KDDE---IQLKQNELNDLKESINTY-LERFSCDQQIIQKQQFEIRILQNQIEELKNQ-GE 971

Query: 1178 LETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAE 1237
             E L  +        +  I Q + ++  LN   +       +L+ +++  +  + F  ++
Sbjct: 972  FEKLEFQQQLQIKKQKSNIGQFEDEITSLNNVIEEKEKPTDQLKQNMNDVITNK-FNQSQ 1030

Query: 1238 LWKQHLAQREAD-FQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIV--TMEQVTS 1294
               Q     + D   K     + QL   +S  ++ ++        E   +     E+   
Sbjct: 1031 YVNQIKEFDDFDENNKNSVNEQQQLIDIKSARQRWINETDQELVNEERVLFQKLREENNI 1090

Query: 1295 LQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKV------AFXXXXXXXXXXXXXX 1348
            ++ +L D+E+ L    ++  D    I  L+ E+E  K                       
Sbjct: 1091 IRKQLADQEKELIINNQRIYDHEETILNLQQELEARKYNNNSPRPLDKEINQDEGQIDQD 1150

Query: 1349 XXDLRTENQSYKQ----MQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLE 1404
                + + + Y+Q    +Q Q IL + EEN  LK++             ++ND E  +  
Sbjct: 1151 SEQQQIQQKQYQQKVSNVQPQQILKLREENEILKRNLYDLQLELELNNQKLNDHEQTIQN 1210

Query: 1405 LTHQL------------ELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLT 1452
            L  +L            +L D+++ Q ++     L+Q    F+ +    VE +   ++ +
Sbjct: 1211 LQTELYEKKEKTENFENKLMDNQVSQLSNR--SKLSQEQIRFDQLPDIGVEDQDVADNDS 1268

Query: 1453 YEKESEL---AILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELN 1509
            +E+E  +     L LK  E  N  + +Q+E     +K ++E N  + + ++     + + 
Sbjct: 1269 FEQEENIFQQRQLNLKQQELTNTIKELQEE-----IKQLKEQNKSLQDFINRGSAPSPIY 1323

Query: 1510 KALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRD 1569
               E +  K++++    E +  +   L +++         + SK Q    F  D +    
Sbjct: 1324 NR-ESDPNKSSKIAQETEKRRQD---LQNQLYEKDQTFSHNKSKSQVLFEFTQDEENQAG 1379

Query: 1570 EQLDNTMNKELL 1581
            + L   + KE L
Sbjct: 1380 DDLAEDIKKERL 1391



 Score = 83.0 bits (196), Expect = 6e-14
 Identities = 146/846 (17%), Positives = 345/846 (40%), Gaps = 55/846 (6%)

Query: 764  IENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDEL 823
            + NI    +  +S +  L+      +     LE K   L      +     E  I+   L
Sbjct: 92   LSNITQTKNTLESNLNELKYHENAQKLELLELESKCQILQEETSTQTNNLKEENIRLQGL 151

Query: 824  VNRLAV-LMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEK 882
               L + + D       QL +IE  N++    N+   ++ +NL +     +Q  N     
Sbjct: 152  NETLEIQIKDQKSQNIDQLKQIEQINEKYNLINEQFTQQQKNLSL----FEQTIN----- 202

Query: 883  ANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRD 942
              R  + E ++ + + +L  L    +++   H  LI++K++++  +  +   +I+  + +
Sbjct: 203  EQRNQIQEIDNGQSKQELNILAIQHEQLKLLHNQLIIEKEQQLSYINKQCQQEIDVLMIE 262

Query: 943  KKVL---NEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQ 999
             K L   N K E+ I+ +  +  QL +     +++N+ ++E     L   ++    +   
Sbjct: 263  NKDLSFQNHKLEQKIKKLQLINNQLIDQ----QDINLKIQENELKQLYFGEQQKNLELDI 318

Query: 1000 SPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLEN 1059
              + T Q I  + +LN  L+QK ++   L Q++N  +   + +     ++L Q     E+
Sbjct: 319  KINETYQRIESLQQLNEQLEQKIKD---LEQQLNVQEQQNVDL-HKVNNELVQNNNIQES 374

Query: 1060 MEEEMQRVSK---QLLDSKQHNEELQILVREQDDQIKELK-------ETKLTFEMNIPKT 1109
              ++++ +++   Q +    + +EL +  ++ +D I +LK       + ++T    +PK 
Sbjct: 375  NLQKLKIINEIQLQKITDLANGQELNL--QKLNDPISQLKLLPQKFQKLEITLLRLLPKL 432

Query: 1110 EGMIISS---TIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQER---SVLQEQSAK 1163
               II       + ++  +NN+D               Q  ++ +Q +   S L+  + K
Sbjct: 433  RQKIIQQQDLISQLINKYSNNIDDLNQQLLKQQDKSN-QLYDQVLQNQELNSELKNLNDK 491

Query: 1164 LNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTE-NDNLLSTVAELRS 1222
            L +E Q+  +K+ +   LN ++   +    +Q  + +++L+QL  +  D      +E++ 
Sbjct: 492  LESEKQQNISKLEKQIDLNEQIGAQNAFLSQQKQEFENELKQLQQDYQDQQSKWNSEIQQ 551

Query: 1223 SISSAVDQRGFEIAELWKQHLAQREADFQKTEHELR-VQLSAFESKYEQLLDSVQSSTQE 1281
             I      +     E++ Q L ++    Q    E++  Q+++   + E +L   Q     
Sbjct: 552  KIQENSTIKNEN--EIFNQELTKKNEQIQILSKEIKQFQINSQCEQEELILKRQQEIKII 609

Query: 1282 ETNKIVTMEQVTSLQNKLQDKE-EHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXX 1340
            E           + QN+ Q+K+   L  ++ K+       ++L  E+   ++        
Sbjct: 610  EVKISEQQNNFLNNQNQYQEKQILRLNFIKNKFNKEQEVTKLLNIELNSIQMEMKQLIDR 669

Query: 1341 XXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEA 1400
                      + +    + K ++ ++  ++N +  Q+KK               + ++  
Sbjct: 670  HLVQSSSLNQENQILQDNLK-IEREAKEDLNSQIVQIKKQIVKLNNTINQKDQEI-ESFR 727

Query: 1401 KVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELA 1460
            K+ +  ++ ++ D +          ++ + N +F+   QQL +    I ++   K+ E+ 
Sbjct: 728  KINDALNERQIIDKQALSNDLN---SIQESNSQFKQQIQQLQDQINNINEILLAKDQEIQ 784

Query: 1461 ILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTN 1520
             L+ K+ +         +E EI+ V+L       + +    + ++ +L   LE++  K  
Sbjct: 785  TLKQKLQDQVKEINLKTQEYEIKNVELNNIKEEGLKKLKCKDDEILQLQDNLEQQKIKYE 844

Query: 1521 E----MQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTM 1576
                 +Q  LE  +I +    +EI+ + N          K +   +   QG+  Q +  +
Sbjct: 845  SQSLVLQQNLEQLQINLKKKEEEISRI-NSANEELKASNKELQDQNKILQGQSLQQEQNL 903

Query: 1577 NKELLD 1582
            N  +++
Sbjct: 904  NLRIVN 909



 Score = 56.0 bits (129), Expect = 8e-06
 Identities = 141/742 (19%), Positives = 308/742 (41%), Gaps = 62/742 (8%)

Query: 147  LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXX 206
            L + +K +  A   L  ++  ++  I+ L   IN+KDQ IE+  K               
Sbjct: 684  LQDNLKIEREAKEDLNSQIVQIKKQIVKLNNTINQKDQEIESFRKINDALNERQIIDKQA 743

Query: 207  XXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLL-KDIESKDVRISSLEEANKL-LEAAR 264
                    ++  ++ ++    ++ +  +  + LL KD E + ++    ++  ++ L+   
Sbjct: 744  LSNDLNSIQESNSQFKQQIQQLQDQINNINEILLAKDQEIQTLKQKLQDQVKEINLKTQE 803

Query: 265  FEI-SLEHSKLAQE-LEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMT 322
            +EI ++E + + +E L++              L +Q I+   +     +    L+I N+ 
Sbjct: 804  YEIKNVELNNIKEEGLKKLKCKDDEILQLQDNLEQQKIKYESQSLVLQQNLEQLQI-NLK 862

Query: 323  ELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKM 382
            +  ++I  +   N +++ +NKEL+++   +  +S       ++   L  R        + 
Sbjct: 863  KKEEEISRINSANEELKASNKELQDQNKILQGQSL------QQEQNLNLRIVNIEAIIED 916

Query: 383  KSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXX 442
            K    QL    LN D  + IN   + +     Q + K   +   + ++ +          
Sbjct: 917  KDDEIQLKQNELN-DLKESIN-TYLERFSCDQQIIQKQQFEIRILQNQIEELKNQGEFE- 973

Query: 443  XGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKD-VNVKDL 501
              K     QLQ++ Q+   G     + +    + E  K  +QLKQ +ND I +  N    
Sbjct: 974  --KLEFQQQLQIKKQKSNIGQFEDEITSLNNVIEEKEKPTDQLKQNMNDVITNKFNQSQY 1031

Query: 502  IEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLT 561
            + ++K          D+ D  NKN +    N + +L  ++     +  ++++++E+V   
Sbjct: 1032 VNQIKEF--------DDFDENNKNSV----NEQQQLIDIKSARQRW--INETDQELV--- 1074

Query: 562  EELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESD-VYKKMIEMENLAETRLKAISLLE 620
             E   L QK   L EE   ++  L D +   +I +  +Y     + NL +  L+A     
Sbjct: 1075 NEERVLFQK---LREENNIIRKQLADQEKELIINNQRIYDHEETILNL-QQELEARKYNN 1130

Query: 621  SQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELAL 680
            +    L +E++  + + D+ + +   I Q Q  Q  S ++   + +  +     K+ L  
Sbjct: 1131 NSPRPLDKEINQDEGQIDQ-DSEQQQIQQKQYQQKVSNVQPQQILKLREENEILKRNLYD 1189

Query: 681  VIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLE-KMSAEKISELLAKI 739
            +   L+L+ ++L        ND E  +  LQ  + E  + T+  E K+   ++S+L    
Sbjct: 1190 LQLELELNNQKL--------NDHEQTIQNLQTELYEKKEKTENFENKLMDNQVSQL---S 1238

Query: 740  NHEEQSKIQTQFG--IDAKIQERDLY-IENIESELSKYKSRICRLEE-----SIAVMEDR 791
            N  + S+ Q +F    D  ++++D+   ++ E E + ++ R   L++     +I  +++ 
Sbjct: 1239 NRSKLSQEQIRFDQLPDIGVEDQDVADNDSFEQEENIFQQRQLNLKQQELTNTIKELQEE 1298

Query: 792  RYSLERKADQLGSYLQEKQKAYSEYTIQED-ELVNRLAVLMDHDRV-VEKQLLEIEHENK 849
               L+ +   L  ++         Y  + D    +++A   +  R  ++ QL E +    
Sbjct: 1299 IKQLKEQNKSLQDFINRGSAPSPIYNRESDPNKSSKIAQETEKRRQDLQNQLYEKDQTFS 1358

Query: 850  ELQKKNQILLEENQNLQISLSD 871
              + K+Q+L E  Q+ +    D
Sbjct: 1359 HNKSKSQVLFEFTQDEENQAGD 1380


>UniRef50_UPI00006CB2D6 Cluster: Viral A-type inclusion protein repeat
            containing protein; n=1; Tetrahymena thermophila
            SB210|Rep: Viral A-type inclusion protein repeat
            containing protein - Tetrahymena thermophila SB210
          Length = 1671

 Score =  133 bits (321), Expect = 4e-29
 Identities = 175/900 (19%), Positives = 395/900 (43%), Gaps = 46/900 (5%)

Query: 451  QLQLEHQQHMEGPSLIHVG-TNTEDVNEIAKVQ---EQLKQELNDEIKDVNVKDLIEKLK 506
            Q+ L + +H + P  I +   N+E  N+I K++   E L  +  D+  ++ +  L +K  
Sbjct: 584  QMNLLNNKHKKDPHQIELEYQNSELRNQIMKLKNEIEMLNLKRKDDNSNIQIDLLTKKNT 643

Query: 507  SAEEQITQLNDEIDAANKN--MIKVKSNHKLKLKQMQKTIDNFSKV-SDSNKEIVRLTEE 563
              ++QI +L  +++  N +   +K  S+ + +L +  K   N        NKE       
Sbjct: 644  LLQDQINKLEQQLNQVNNSNEYVKAISSLQKQLDERDKAYQNLHLYYQKDNKENYISAAN 703

Query: 564  LHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDV---YKKMIEMENLAETRLKAISLLE 620
             +  +  V + EE K   +L+    +   +++      + +++  +N  + +L+     +
Sbjct: 704  QNDANNAVNKTEEAKIIEKLNTRVANLTVLLQQSAKISFNQILRKQNDKQQKLQDKIFQQ 763

Query: 621  SQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELAL 680
             QK    QE    ++K   +      I Q++        K + L +Q       K E+ L
Sbjct: 764  EQKLIASQE-ESQKEKNKYISFHEEKIKQIEQRYYSENKKVLSLLDQTK--EQHKDEINL 820

Query: 681  VIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKIN 740
            + + +K  +  +    K L+N +E I  +L + I +     ++L K S +++   L   N
Sbjct: 821  LNQKIKSQECDMIEKTKQLKNAQEQIA-RLNSQISQKQKEYEELNKKS-QQVENRLKTDN 878

Query: 741  HEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKAD 800
             ++ +++Q+Q   D++  ++ L    +E++L+  +S    L+       + +  L+ K +
Sbjct: 879  AKQVTELQSQLQKDSEKYKKRL--AQLETDLANKQSV---LQNQTKDFNNVKRDLDLKHE 933

Query: 801  QLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKN---QI 857
            +      E Q+  +E    + +++N    + + D+ VEK  LEI+  NK+ Q  N   Q 
Sbjct: 934  EYEKVQYELQQVQNERDRLKKDVMNLKNRIENLDQTVEKNRLEIQQLNKQNQALNNEKQS 993

Query: 858  LLEENQNLQISLSDMQQHYNALVEKANRTDLAESES-TKYQTQLRDLESNLKRITHEHQT 916
            + E+ Q  +  + D+Q+    +++     +   S   ++ ++Q  DL+     I + ++ 
Sbjct: 994  ISEDIQKDKQQVQDLQKRLTQILDSVKSLESERSRLLSQIESQKLDLDKKKIEIDNLNKQ 1053

Query: 917  LIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEK---YEKNIE-YVTQ---LEAQLQEYKN 969
            +  Q  +  + LE    +Q+   ++    LNE+   Y+  I+ + T+   LEA +Q    
Sbjct: 1054 VYEQSNERAQQLEKLMESQMNEKLKIS-ALNEQVQIYKIEIDQFKTKMQILEADIQARDE 1112

Query: 970  NIENLNMNVEELNKMNLELIDKHVQK---QQTQSPDYTEQYINEINKLNALLKQKDEEII 1026
             I+ LN N+E   K+ ++  DK ++    +Q++     EQ    I  LNA ++Q   E  
Sbjct: 1113 KIKILNKNIET-QKITIDENDKKIESLVSEQSKVIAENEQKNQLITNLNAAIEQALIECE 1171

Query: 1027 ALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVR 1086
               +  N+ +V       +Y+ +L +   ++  +   +    ++  ++   N EL   + 
Sbjct: 1172 IQQKNANSKKVELEEKQEEYKHELERLQNEINELGRNLATCKERERETNNKNVELIQQIE 1231

Query: 1087 EQDDQI--KELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKV 1144
            E +  +  KE +  ++  EMN+ K        +++ ++ D    D            L  
Sbjct: 1232 EANHNLNQKEQELNQIVEEMNLNKNHINSNEMSLKQLNLDLKERDDYVSNLQDEVKNL-T 1290

Query: 1145 QEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLE 1204
            Q+ E+  ++    Q++   LN+++ +    +  +E  N EL        + +  L+S L+
Sbjct: 1291 QQLEDLQRQDLQNQQEIENLNSQINKLKNNLNSMEDKNQELQSKTNNLLQNVIDLQSSLQ 1350

Query: 1205 QLNTENDNLLSTVAELRSSISSAVDQRGFEIA---ELWKQHLAQREADFQKTEHELRVQL 1261
            QL  E + +      L+ S+    +++   I    E  K++   + +      H   +  
Sbjct: 1351 QLRVEKELIEQNNQLLQESLQKEKEEKEIAIRCQDEQEKEYEKLKNSTICIDAHTQALDK 1410

Query: 1262 SAFESKYEQL-LDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQI 1320
               ++  ++L ++  Q   ++   +++T E  T++Q++ +  + H + +QE Y   I+++
Sbjct: 1411 LEIKNDQQKLEIEKQQEQLEQFAQQLITAE--TTIQSQKKQLDGH-KIIQENYLKTISEL 1467



 Score =  121 bits (292), Expect = 1e-25
 Identities = 176/895 (19%), Positives = 393/895 (43%), Gaps = 66/895 (7%)

Query: 327  KIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISR-KSGRNTASKMKSP 385
            +I+LL   N  ++    +LE +L  +   ++ V + S     L  R K+ +N     +  
Sbjct: 634  QIDLLTKKNTLLQDQINKLEQQLNQVNNSNEYVKAISSLQKQLDERDKAYQNLHLYYQKD 693

Query: 386  WSQLSSETLNQ-DTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXG 444
              +      NQ D +  +NK E AK   +I+ LN  + +   V+ ++             
Sbjct: 694  NKENYISAANQNDANNAVNKTEEAK---IIEKLNTRVANLT-VLLQQSAKISFNQILRKQ 749

Query: 445  KDTLIAQLQLEHQQHMEGPSLIHVGTNTE-DVNEIAKVQEQLKQELNDEIKDVNVKDLIE 503
             D    Q +L+ +   +   LI     ++ + N+     E+  +++       N K ++ 
Sbjct: 750  NDK---QQKLQDKIFQQEQKLIASQEESQKEKNKYISFHEEKIKQIEQRYYSEN-KKVLS 805

Query: 504  KLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEE 563
             L   +EQ     DEI+  N+ +   + +   K KQ++   +  +++   N +I +  +E
Sbjct: 806  LLDQTKEQH---KDEINLLNQKIKSQECDMIEKTKQLKNAQEQIARL---NSQISQKQKE 859

Query: 564  LHHLSQKVAELEEE-KGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQ 622
               L++K  ++E   K +    + +  S    +S+ YKK   +  L        S+L++Q
Sbjct: 860  YEELNKKSQQVENRLKTDNAKQVTELQSQLQKDSEKYKK--RLAQLETDLANKQSVLQNQ 917

Query: 623  KFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVI 682
              D       L  K++E E    ++ Q+Q+++   +   ++L+ +I+ L  + ++  L I
Sbjct: 918  TKDFNNVKRDLDLKHEEYEKVQYELQQVQNERDRLKKDVMNLKNRIENLDQTVEKNRLEI 977

Query: 683  ENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHE 742
            + L    + L    + +  D +    ++Q+  +    + D ++ + +E+ S LL++I  +
Sbjct: 978  QQLNKQNQALNNEKQSISEDIQKDKQQVQDLQKRLTQILDSVKSLESER-SRLLSQIESQ 1036

Query: 743  EQSKIQTQFGID-------AKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSL 795
            +    + +  ID        +  ER   +E +       K +I  L E + + +      
Sbjct: 1037 KLDLDKKKIEIDNLNKQVYEQSNERAQQLEKLMESQMNEKLKISALNEQVQIYKIEIDQF 1096

Query: 796  ERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKN 855
            + K   L + +Q + +   +  I    +  +   + ++D+ +E  + E      E ++KN
Sbjct: 1097 KTKMQILEADIQARDE---KIKILNKNIETQKITIDENDKKIESLVSEQSKVIAENEQKN 1153

Query: 856  QILLEENQNLQISLSDMQ-QHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEH 914
            Q++   N  ++ +L + + Q  NA    + + +L E +  +Y+ +L  L++ +  +    
Sbjct: 1154 QLITNLNAAIEQALIECEIQQKNA---NSKKVELEEKQE-EYKHELERLQNEINELGRNL 1209

Query: 915  QTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENL 974
             T   ++++E  +  +E   QIE A  +   LN+K ++    + Q+  ++   KN+I + 
Sbjct: 1210 ATC-KERERETNNKNVELIQQIEEANHN---LNQKEQE----LNQIVEEMNLNKNHINSN 1261

Query: 975  NMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINN 1034
             M++++LN ++L+  D +V   Q +  + T+Q + ++ + +    Q  +EI  LN +IN 
Sbjct: 1262 EMSLKQLN-LDLKERDDYVSNLQDEVKNLTQQ-LEDLQRQDL---QNQQEIENLNSQINK 1316

Query: 1035 AQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKE 1094
             + +  SM  D   +L   T  L     ++Q   +QL   K+  E+   L++E   + KE
Sbjct: 1317 LKNNLNSM-EDKNQELQSKTNNLLQNVIDLQSSLQQLRVEKELIEQNNQLLQESLQKEKE 1375

Query: 1095 LKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQER 1154
             KE  +  +    K    + +STI     DA+               L+++ +++ ++  
Sbjct: 1376 EKEIAIRCQDEQEKEYEKLKNSTI---CIDAHT---------QALDKLEIKNDQQKLE-- 1421

Query: 1155 SVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTE 1209
              +++Q  +L    Q+  T    +++   +L GH ++ +  +  +     +LN E
Sbjct: 1422 --IEKQQEQLEQFAQQLITAETTIQSQKKQLDGHKIIQENYLKTISELSSKLNVE 1474



 Score =  116 bits (279), Expect = 5e-24
 Identities = 214/1078 (19%), Positives = 463/1078 (42%), Gaps = 92/1078 (8%)

Query: 483  EQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSN-HKLKLKQMQ 541
            E+L +  N+  +     DL ++L+  E  + Q     D   +  + + +N HK    Q++
Sbjct: 541  EKLPKIENEHDEKDKYFDLFKQLELPEYGLKQEEMIADLKKELQMNLLNNKHKKDPHQIE 600

Query: 542  KTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYK- 600
                N    S+   +I++L  E+  L+ K    +++  N+Q+ L+      +++  + K 
Sbjct: 601  LEYQN----SELRNQIMKLKNEIEMLNLK---RKDDNSNIQIDLLT-KKNTLLQDQINKL 652

Query: 601  -KMIEMENLAETRLKAISLLESQ---KFDLVQELHILQQKYDEVEDKLADISQLQSDQVC 656
             + +   N +   +KAIS L+ Q   +    Q LH+  QK D  E+ ++  +Q  ++   
Sbjct: 653  EQQLNQVNNSNEYVKAISSLQKQLDERDKAYQNLHLYYQK-DNKENYISAANQNDANNAV 711

Query: 657  SEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYI-Q 715
            ++ +   + E+++   A+     L+ ++ K+   Q+       +NDK+    KLQ+ I Q
Sbjct: 712  NKTEEAKIIEKLNTRVANLT--VLLQQSAKISFNQILRK----QNDKQQ---KLQDKIFQ 762

Query: 716  ENMDLTDKLEKMSAEK---ISELLAKINHEEQSKIQTQFGIDAKI-QERDLYIENIESEL 771
            +   L    E+   EK   IS    KI   EQ        + + + Q ++ + + I    
Sbjct: 763  QEQKLIASQEESQKEKNKYISFHEEKIKQIEQRYYSENKKVLSLLDQTKEQHKDEINLLN 822

Query: 772  SKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLM 831
             K KS+ C + E    +++ +  + R    L S + +KQK Y E   +  ++ NRL    
Sbjct: 823  QKIKSQECDMIEKTKQLKNAQEQIAR----LNSQISQKQKEYEELNKKSQQVENRLKT-- 876

Query: 832  DHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAES 891
            D+ + V +   +++ ++++ +K+   L  +  N Q  L +  + +N +       DL   
Sbjct: 877  DNAKQVTELQSQLQKDSEKYKKRLAQLETDLANKQSVLQNQTKDFNNVKRDL---DLKHE 933

Query: 892  ESTKYQTQLRDLESNLKRITHEHQTL---IVQKKKEIED--LEIE-FNTQIESAIRDKKV 945
            E  K Q +L+ +++   R+  +   L   I    + +E   LEI+  N Q ++   +K+ 
Sbjct: 934  EYEKVQYELQQVQNERDRLKKDVMNLKNRIENLDQTVEKNRLEIQQLNKQNQALNNEKQS 993

Query: 946  LNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEEL-NKMNLELIDKHVQKQQTQSPDYT 1004
            ++E  +K+ + V  L+ +L +  +++++L      L +++  + +D  + K++ +  +  
Sbjct: 994  ISEDIQKDKQQVQDLQKRLTQILDSVKSLESERSRLLSQIESQKLD--LDKKKIEIDNLN 1051

Query: 1005 EQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEM 1064
            +Q   + N+    L++  E    +N+K+  + ++    V  Y+ ++ QF TK++ +E ++
Sbjct: 1052 KQVYEQSNERAQQLEKLMES--QMNEKLKISALN--EQVQIYKIEIDQFKTKMQILEADI 1107

Query: 1065 QRVSKQLLDSKQHNEELQILVREQDDQIKEL--KETKLTFEMNIPKTEGMIISSTIEPMS 1122
            Q   +++    ++ E  +I + E D +I+ L  +++K+  E N  K +  +I++    + 
Sbjct: 1108 QARDEKIKILNKNIETQKITIDENDKKIESLVSEQSKVIAE-NEQKNQ--LITNLNAAIE 1164

Query: 1123 DDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLN 1182
                  +            L+ +++EE+  E   LQ +  +L   L  C  +  + ET N
Sbjct: 1165 QALIECEIQQKNANSKKVELE-EKQEEYKHELERLQNEINELGRNLATCKER--ERETNN 1221

Query: 1183 TELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQH 1242
                     N E I Q++     LN +   L   V E+  +  + ++     + +L    
Sbjct: 1222 K--------NVELIQQIEEANHNLNQKEQELNQIVEEMNLN-KNHINSNEMSLKQL-NLD 1271

Query: 1243 LAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDK 1302
            L +R+      + E++      E    Q L + Q    E  N      Q+  L+N L   
Sbjct: 1272 LKERDDYVSNLQDEVKNLTQQLEDLQRQDLQNQQEI--ENLNS-----QINKLKNNLNSM 1324

Query: 1303 EEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQM 1362
            E+  + LQ K  +++  +  L+S ++  +V                  +   +  + +  
Sbjct: 1325 EDKNQELQSKTNNLLQNVIDLQSSLQQLRVEKELIEQNNQLLQESLQKEKEEKEIAIRCQ 1384

Query: 1363 QEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQK-TH 1421
             EQ      +E  +LK S+                 + + LE+  Q E  +    Q  T 
Sbjct: 1385 DEQ-----EKEYEKLKNSTICIDAHTQALDKLEIKNDQQKLEIEKQQEQLEQFAQQLITA 1439

Query: 1422 EYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESE 1481
            E TI   ++  +   + Q+   Y K I +L+ +       L ++  ++   +E  Q E  
Sbjct: 1440 ETTIQSQKKQLDGHKIIQE--NYLKTISELSSK-------LNVEKKDSECQWEEEQDEKM 1490

Query: 1482 IERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEM-QTALENQEIEIVTLND 1538
            I       +   K+ +S+  NK++  +++   E +  T  + +T++  + I    L +
Sbjct: 1491 ISLSTYEAQKFRKLLKSIDHNKKIPIMSQKNIEHIDITQALKKTSIIQESINFTKLEE 1548



 Score =  113 bits (271), Expect = 5e-23
 Identities = 167/846 (19%), Positives = 361/846 (42%), Gaps = 54/846 (6%)

Query: 306  EKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKK 365
            E+ +I EK +  +AN+T L ++   +       +Q +K+ + +      E K ++S  + 
Sbjct: 715  EEAKIIEKLNTRVANLTVLLQQSAKISFNQILRKQNDKQQKLQDKIFQQEQKLIASQEES 774

Query: 366  GSPLISRKSGRNTASK-MKSPWSQLSSETLNQ-DTDKKINKNEIAKLEMVIQSLNKDLVD 423
                    S      K ++  +   + + L+  D  K+ +K+EI  L   I+S   D+++
Sbjct: 775  QKEKNKYISFHEEKIKQIEQRYYSENKKVLSLLDQTKEQHKDEINLLNQKIKSQECDMIE 834

Query: 424  KEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQE 483
            K   +                K     +L  + QQ        +    TE  +++ K  E
Sbjct: 835  KTKQLKNAQEQIARLNSQISQKQKEYEELNKKSQQVENRLKTDNAKQVTELQSQLQKDSE 894

Query: 484  QLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVK------SNHKLKL 537
            + K+ L     D+  K  +  L++  +    +  ++D  ++   KV+       N + +L
Sbjct: 895  KYKKRLAQLETDLANKQSV--LQNQTKDFNNVKRDLDLKHEEYEKVQYELQQVQNERDRL 952

Query: 538  KQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESD 597
            K+    + N  +  D   E  RL  E+  L+++   L  EK ++     D    +    D
Sbjct: 953  KKDVMNLKNRIENLDQTVEKNRL--EIQQLNKQNQALNNEKQSIS---EDIQKDKQQVQD 1007

Query: 598  VYKKMIE----MENLAETRLKAISLLESQKFDL----VQELHILQQKYDEVEDKLADISQ 649
            + K++ +    +++L   R + +S +ESQK DL    ++  ++ +Q Y++  ++   + +
Sbjct: 1008 LQKRLTQILDSVKSLESERSRLLSQIESQKLDLDKKKIEIDNLNKQVYEQSNERAQQLEK 1067

Query: 650  LQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNK 709
            L   Q+  ++K   L EQ+        +    ++ L+ D +     IK L  + E     
Sbjct: 1068 LMESQMNEKLKISALNEQVQIYKIEIDQFKTKMQILEADIQARDEKIKILNKNIETQKIT 1127

Query: 710  LQNYIQENMDLTDKLEKMSA--EKISELLAKINHE-EQSKIQ---TQFGIDAKIQERDLY 763
            +    ++   L  +  K+ A  E+ ++L+  +N   EQ+ I+    Q   ++K  E +  
Sbjct: 1128 IDENDKKIESLVSEQSKVIAENEQKNQLITNLNAAIEQALIECEIQQKNANSKKVELEEK 1187

Query: 764  IENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDEL 823
             E  + EL + ++ I  L  ++A  ++R      K  +L   ++E     ++   + +++
Sbjct: 1188 QEEYKHELERLQNEINELGRNLATCKERERETNNKNVELIQQIEEANHNLNQKEQELNQI 1247

Query: 824  VNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKA 883
            V  + +  +H    E  L ++  + KE       L +E +NL   L D+Q+     ++  
Sbjct: 1248 VEEMNLNKNHINSNEMSLKQLNLDLKERDDYVSNLQDEVKNLTQQLEDLQRQD---LQNQ 1304

Query: 884  NRTDLAESESTKYQTQLRDLESNLKRITHEHQTL---IVQKKKEIEDLEIEFN-TQIESA 939
               +   S+  K +  L  +E   + +  +   L   ++  +  ++ L +E    +  + 
Sbjct: 1305 QEIENLNSQINKLKNNLNSMEDKNQELQSKTNNLLQNVIDLQSSLQQLRVEKELIEQNNQ 1364

Query: 940  IRDKKVLNEKYEKNIEYVTQ--LEAQLQEYKNNIENLNMNVEELNKMNLELIDK--HVQK 995
            +  + +  EK EK I    Q   E + ++ KN+   ++ + + L+K+ ++   +   ++K
Sbjct: 1365 LLQESLQKEKEEKEIAIRCQDEQEKEYEKLKNSTICIDAHTQALDKLEIKNDQQKLEIEK 1424

Query: 996  QQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTT 1055
            QQ Q   + +Q I     + +  KQ D   I     +    +S +S   + E K ++   
Sbjct: 1425 QQEQLEQFAQQLITAETTIQSQKKQLDGHKIIQENYLKT--ISELSSKLNVEKKDSECQW 1482

Query: 1056 KLENMEEEMQRVS-------KQLLDSKQHNEELQILVR---EQDDQIKELKETKLTFE-M 1104
            + E  +E+M  +S       ++LL S  HN+++ I+ +   E  D  + LK+T +  E +
Sbjct: 1483 E-EEQDEKMISLSTYEAQKFRKLLKSIDHNKKIPIMSQKNIEHIDITQALKKTSIIQESI 1541

Query: 1105 NIPKTE 1110
            N  K E
Sbjct: 1542 NFTKLE 1547



 Score =  104 bits (249), Expect = 2e-20
 Identities = 167/826 (20%), Positives = 363/826 (43%), Gaps = 76/826 (9%)

Query: 795  LERKADQLGSYLQE-KQKAYSEYTIQEDELVNRLAV-----LMDHDRVVEKQLLEIEHEN 848
            +E + D+   Y    KQ    EY ++++E++  L       L+++    +   +E+E++N
Sbjct: 546  IENEHDEKDKYFDLFKQLELPEYGLKQEEMIADLKKELQMNLLNNKHKKDPHQIELEYQN 605

Query: 849  KELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLK 908
             EL  +NQI+  +N+   ++L     + N  +      DL   ++T  Q Q+  LE  L 
Sbjct: 606  SEL--RNQIMKLKNEIEMLNLKRKDDNSNIQI------DLLTKKNTLLQDQINKLEQQLN 657

Query: 909  RITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYK 968
            ++ + ++ +     K I  L+ + + + + A ++  +  +K  K   Y++   A  Q   
Sbjct: 658  QVNNSNEYV-----KAISSLQKQLDER-DKAYQNLHLYYQKDNKE-NYIS---AANQNDA 707

Query: 969  NNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTE---QYINEINKLNALLKQKDEEI 1025
            NN  N     + + K+N  + +  V  QQ+    + +   +  ++  KL   + Q+++++
Sbjct: 708  NNAVNKTEEAKIIEKLNTRVANLTVLLQQSAKISFNQILRKQNDKQQKLQDKIFQQEQKL 767

Query: 1026 IALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQIL- 1084
            IA  ++    +  Y+S    +E K+ Q   +  +  +++  +  Q    +QH +E+ +L 
Sbjct: 768  IASQEESQKEKNKYISF---HEEKIKQIEQRYYSENKKVLSLLDQT--KEQHKDEINLLN 822

Query: 1085 --VREQD-DQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXX 1141
              ++ Q+ D I++ K+ K   E  I +    I     E   ++ N               
Sbjct: 823  QKIKSQECDMIEKTKQLKNAQEQ-IARLNSQISQKQKE--YEELNKKSQQVENRLKTDNA 879

Query: 1142 LKVQEEEEFIQERSV-LQEQSAKLNTELQECYTKIIQLETLNTELTGHDV-VNQEQINQL 1199
             +V E +  +Q+ S   +++ A+L T+L    + ++Q +T +      D+ +  E+  ++
Sbjct: 880  KQVTELQSQLQKDSEKYKKRLAQLETDLANKQS-VLQNQTKDFNNVKRDLDLKHEEYEKV 938

Query: 1200 KSKLEQLNTENDNLLSTVAELRSSISS---AVDQRGFEIAELWKQHLA--QREADFQKTE 1254
            + +L+Q+  E D L   V  L++ I +    V++   EI +L KQ+ A    +    +  
Sbjct: 939  QYELQQVQNERDRLKKDVMNLKNRIENLDQTVEKNRLEIQQLNKQNQALNNEKQSISEDI 998

Query: 1255 HELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTME-QVTSLQNKLQDKEEHLRNLQEKY 1313
             + + Q+   + +  Q+LDSV+S   E +  +  +E Q   L  K  + +   + + E+ 
Sbjct: 999  QKDKQQVQDLQKRLTQILDSVKSLESERSRLLSQIESQKLDLDKKKIEIDNLNKQVYEQS 1058

Query: 1314 ADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYK---QMQEQSIL-- 1368
             +   Q+E L     +EK+                    +T+ Q  +   Q +++ I   
Sbjct: 1059 NERAQQLEKLMESQMNEKLKISALNEQVQIYKIEID-QFKTKMQILEADIQARDEKIKIL 1117

Query: 1369 --NINEENAQLKKSSXXXXXXXXXXXXRVNDAEAK---VLELTHQLE--LKDSEIYQKT- 1420
              NI  +   + ++              + + E K   +  L   +E  L + EI QK  
Sbjct: 1118 NKNIETQKITIDENDKKIESLVSEQSKVIAENEQKNQLITNLNAAIEQALIECEIQQKNA 1177

Query: 1421 HEYTITLTQRNDEFENVRQQLV-EYEKRIEDLTYEKESELA-----ILRLKMHENANHYE 1474
            +   + L ++ +E+++  ++L  E  +   +L   KE E       +  ++  E ANH  
Sbjct: 1178 NSKKVELEEKQEEYKHELERLQNEINELGRNLATCKERERETNNKNVELIQQIEEANH-N 1236

Query: 1475 TMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALEN--QEIE 1532
              QKE E+ ++  +EE+N+      S    + +LN  L+E     + +Q  ++N  Q++E
Sbjct: 1237 LNQKEQELNQI--VEEMNLNKNHINSNEMSLKQLNLDLKERDDYVSNLQDEVKNLTQQLE 1294

Query: 1533 IVTLNDEITNLQNMVRASS--SKIQKHVSFASDTKQGRDEQLDNTM 1576
             +   D + N Q +   +S  +K++ +++   D  Q    + +N +
Sbjct: 1295 DLQRQD-LQNQQEIENLNSQINKLKNNLNSMEDKNQELQSKTNNLL 1339



 Score = 93.1 bits (221), Expect = 6e-17
 Identities = 210/1127 (18%), Positives = 467/1127 (41%), Gaps = 82/1127 (7%)

Query: 477  EIAKVQEQLKQELN--DEIKDVNVKDLIEKLKSAEEQITQLNDEIDA-ANKNMIKVKSNH 533
            +++K+ +     +N  ++IK  + K+  E++ S + QI      I   +N+N+  +K   
Sbjct: 297  DVSKMDQWKSHCINHYEKIKKTHSKEQ-EEISSLKRQIKDQQATIQQLSNENIETIKKFD 355

Query: 534  KLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVD-YDSGR 592
               L+    T+ +F+ V +  K + +  + +    Q    L+    N  L   D      
Sbjct: 356  DQCLEGKNYTLTSFNGVYEEYKNLRKCIQYIIDNQQDEYTLKTSLDNCMLQCQDKLKDQE 415

Query: 593  MIESDVYKKMIEMEN----LAETRLKAISLLESQKFDLVQELHILQQ-KYDEVEDKLADI 647
             IE  + + +  + N    + E++ K    ++  +    Q L+ L    YD+++    DI
Sbjct: 416  KIEKQITQYIDALGNYITSIWESKFKQFQRMQQYQQKFTQILNGLNTITYDKLKSLEPDI 475

Query: 648  SQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIM 707
            S+L+ D   S++   +            KE++   E   L     YG     +   E  M
Sbjct: 476  SRLEKD--ISDLTKPYTF--FTNFKVILKEVSRRNEFNSLLDNPNYGKCMPKDFIPELNM 531

Query: 708  NKLQNYIQENMDLTDKLEKMSAEKIS--ELLAKINHEEQSKIQTQFGIDAKIQERDLYIE 765
            N ++ Y Q N +   K+E    EK    +L  ++   E    Q +   D K   ++L + 
Sbjct: 532  N-VKPYPQ-NYEKLPKIENEHDEKDKYFDLFKQLELPEYGLKQEEMIADLK---KELQMN 586

Query: 766  NIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVN 825
             + ++  K   +I  LE   + + ++   L+ + + L   L+ K        IQ D L  
Sbjct: 587  LLNNKHKKDPHQI-ELEYQNSELRNQIMKLKNEIEMLN--LKRKD---DNSNIQIDLLTK 640

Query: 826  RLAVLMDHDRVVEKQLLEIEHENK------ELQKKNQILLEENQNLQISLS-DMQQHYNA 878
            +  +L D    +E+QL ++ + N+       LQK+     +  QNL +    D +++Y  
Sbjct: 641  KNTLLQDQINKLEQQLNQVNNSNEYVKAISSLQKQLDERDKAYQNLHLYYQKDNKENY-- 698

Query: 879  LVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIES 938
             +  AN+ D   + +   + ++  +E    R+ +   T+++Q     +  +I FN  +  
Sbjct: 699  -ISAANQNDANNAVNKTEEAKI--IEKLNTRVAN--LTVLLQ-----QSAKISFNQILRK 748

Query: 939  AIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQT 998
                ++ L +K  +  + +   + + Q+ KN    ++ + E++ ++      ++  K+  
Sbjct: 749  QNDKQQKLQDKIFQQEQKLIASQEESQKEKNKY--ISFHEEKIKQIEQRYYSEN--KKVL 804

Query: 999  QSPDYT-EQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKL 1057
               D T EQ+ +EIN LN  +K ++ ++I   +++ NAQ      ++   S+++Q   + 
Sbjct: 805  SLLDQTKEQHKDEINLLNQKIKSQECDMIEKTKQLKNAQ----EQIARLNSQISQKQKEY 860

Query: 1058 ENMEEEMQRVSKQL-LDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISS 1116
            E + ++ Q+V  +L  D+ +   ELQ  +++  ++ K+        E ++   + ++ + 
Sbjct: 861  EELNKKSQQVENRLKTDNAKQVTELQSQLQKDSEKYKK---RLAQLETDLANKQSVLQNQ 917

Query: 1117 TIEPMSDDANNVDXXXXXXXXXXXXLK-VQEEEEFIQERSV-LQEQSAKLNTELQECYTK 1174
            T +  ++   ++D            L+ VQ E + +++  + L+ +   L+  +++   +
Sbjct: 918  T-KDFNNVKRDLDLKHEEYEKVQYELQQVQNERDRLKKDVMNLKNRIENLDQTVEKNRLE 976

Query: 1175 IIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFE 1234
            I QL   N  L        E I + K +++ L      +L +V  L S  S  + Q   +
Sbjct: 977  IQQLNKQNQALNNEKQSISEDIQKDKQQVQDLQKRLTQILDSVKSLESERSRLLSQIESQ 1036

Query: 1235 IAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTS 1294
              +L K+ +     + Q  E          +    Q+ + ++ S   E  +I  +E +  
Sbjct: 1037 KLDLDKKKIEIDNLNKQVYEQSNERAQQLEKLMESQMNEKLKISALNEQVQIYKIE-IDQ 1095

Query: 1295 LQNKLQDKEEHLRNLQEKYADVINQIEILRSEIE--DEKVAFXXXXXXXXXXXXXXXXDL 1352
             + K+Q  E  ++   EK   +   IE  +  I+  D+K+                   L
Sbjct: 1096 FKTKMQILEADIQARDEKIKILNKNIETQKITIDENDKKIESLVSEQSKVIAENEQKNQL 1155

Query: 1353 RTE-NQSYKQMQEQSIL---NINEENAQLKKSSXXXXXXXXXXXXRVNDAE---AKVLEL 1405
             T  N + +Q   +  +   N N +  +L++               +N+     A   E 
Sbjct: 1156 ITNLNAAIEQALIECEIQQKNANSKKVELEEKQEEYKHELERLQNEINELGRNLATCKER 1215

Query: 1406 THQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLK 1465
              +   K+ E+ Q+  E    L Q+  E   + +++   +  I       E  L  L L 
Sbjct: 1216 ERETNNKNVELIQQIEEANHNLNQKEQELNQIVEEMNLNKNHINS----NEMSLKQLNLD 1271

Query: 1466 MHENANHYETMQKESE--IERVKLIEELNVKITESV-SLNKQVAELNKALEEEVAKTNEM 1522
            + E  ++   +Q E +   ++++ ++  +++  + + +LN Q+ +L   L     K  E+
Sbjct: 1272 LKERDDYVSNLQDEVKNLTQQLEDLQRQDLQNQQEIENLNSQINKLKNNLNSMEDKNQEL 1331

Query: 1523 QTALENQEIEIVTLNDEITNL---QNMVRASSSKIQKHVSFASDTKQ 1566
            Q+   N    ++ L   +  L   + ++  ++  +Q+ +    + K+
Sbjct: 1332 QSKTNNLLQNVIDLQSSLQQLRVEKELIEQNNQLLQESLQKEKEEKE 1378



 Score = 68.5 bits (160), Expect = 1e-09
 Identities = 184/946 (19%), Positives = 382/946 (40%), Gaps = 98/946 (10%)

Query: 718  MDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSR 777
            MD T+       ++    L + N       + Q  +D+K  + D        EL+  + +
Sbjct: 121  MDNTEAAVNFFQQEQENQLKQFNKISLDAKKPQIKLDSKYADTDY---QYPVELNDGQKQ 177

Query: 778  ICRLE-ESIAVMEDRRY----SLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMD 832
            + +L+ ++I  +E + Y    S++RKA +     Q+ ++A  EY IQ   +   L  +++
Sbjct: 178  LVQLKNQNILELEQKFYKFYSSIKRKAYEFIQKWQKVERASKEYEIQYKSIECLLMRVIN 237

Query: 833  HDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESE 892
              +V +    E+  + K L   N+++ +  Q  + SL         + +     D+ + +
Sbjct: 238  EYQVSKNLSTEMHQKIKNL---NEVVSKSVQKYEESLK--------IGKNVELPDVLKKD 286

Query: 893  STKYQTQLRDLESNLKRITH--EHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKV-LNEK 949
            + KY   L D+  ++ ++     H     +K K+    E E  + ++  I+D++  + + 
Sbjct: 287  NKKY---LYDIYYDVSKMDQWKSHCINHYEKIKKTHSKEQEEISSLKRQIKDQQATIQQL 343

Query: 950  YEKNIEYVTQLEAQLQEYKN-NIENLNMNVEE---LNKMNLELIDKHVQKQ--QTQSPDY 1003
              +NIE + + + Q  E KN  + + N   EE   L K    +ID    +   +T   + 
Sbjct: 344  SNENIETIKKFDDQCLEGKNYTLTSFNGVYEEYKNLRKCIQYIIDNQQDEYTLKTSLDNC 403

Query: 1004 TEQYINEINKLNALLKQKDEEIIALNQKINN---AQVSYMSMVSDYESKLAQFTT----- 1055
              Q  +++     + KQ  + I AL   I +   ++      +  Y+ K  Q        
Sbjct: 404  MLQCQDKLKDQEKIEKQITQYIDALGNYITSIWESKFKQFQRMQQYQQKFTQILNGLNTI 463

Query: 1056 ---KLENMEEEMQRVSKQLLD-SKQHN--EELQILVRE--QDDQIKELKETKLTFEMNIP 1107
               KL+++E ++ R+ K + D +K +      +++++E  + ++   L +    +   +P
Sbjct: 464  TYDKLKSLEPDISRLEKDISDLTKPYTFFTNFKVILKEVSRRNEFNSLLDNP-NYGKCMP 522

Query: 1108 KTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTE 1167
            K     ++  ++P   +   +               + ++ E  +     +E  A L  E
Sbjct: 523  KDFIPELNMNVKPYPQNYEKLPKIENEHDEKDKYFDLFKQLELPEYGLKQEEMIADLKKE 582

Query: 1168 LQ-ECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVA-ELRSSIS 1225
            LQ        + +    EL   +   + QI +LK+++E LN +  +  S +  +L +  +
Sbjct: 583  LQMNLLNNKHKKDPHQIELEYQNSELRNQIMKLKNEIEMLNLKRKDDNSNIQIDLLTKKN 642

Query: 1226 SAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLL---------DSVQ 1276
            + +  +  ++ +   Q       ++ K    L+ QL   +  Y+ L          + + 
Sbjct: 643  TLLQDQINKLEQQLNQ--VNNSNEYVKAISSLQKQLDERDKAYQNLHLYYQKDNKENYIS 700

Query: 1277 SSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADV-INQIEILRSEIEDEKVAFX 1335
            ++ Q + N  V   +   +  KL  +  +L  L ++ A +  NQI  LR +  D++    
Sbjct: 701  AANQNDANNAVNKTEEAKIIEKLNTRVANLTVLLQQSAKISFNQI--LRKQ-NDKQQKLQ 757

Query: 1336 XXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINE----ENAQ----LKKSSXXXXXX 1387
                           + + E   Y    E+ I  I +    EN +    L ++       
Sbjct: 758  DKIFQQEQKLIASQEESQKEKNKYISFHEEKIKQIEQRYYSENKKVLSLLDQTKEQHKDE 817

Query: 1388 XXXXXXRVNDAEAKVLELTHQLELK-------DSEIYQKTHEYTITLTQRNDEFENVRQQ 1440
                  ++   E  ++E T QL+         +S+I QK  EY   L +++ + EN  + 
Sbjct: 818  INLLNQKIKSQECDMIEKTKQLKNAQEQIARLNSQISQKQKEYE-ELNKKSQQVEN--RL 874

Query: 1441 LVEYEKRIEDLT--YEKESELAILRLKMHEN--ANHYETMQKES-EIERVKLIEELNVKI 1495
              +  K++ +L    +K+SE    RL   E   AN    +Q ++ +   VK   +L  + 
Sbjct: 875  KTDNAKQVTELQSQLQKDSEKYKKRLAQLETDLANKQSVLQNQTKDFNNVKRDLDLKHEE 934

Query: 1496 TESVSLN-KQVAELNKALEEEVA----KTNEMQTALENQEIEIVTLNDEITNLQNMVRAS 1550
             E V    +QV      L+++V     +   +   +E   +EI  LN +   L N  ++ 
Sbjct: 935  YEKVQYELQQVQNERDRLKKDVMNLKNRIENLDQTVEKNRLEIQQLNKQNQALNNEKQSI 994

Query: 1551 SSKIQKHVSFASDTKQGRDEQLDNTMNKE-----LLDAVPRAELDL 1591
            S  IQK      D ++   + LD+  + E     LL  +   +LDL
Sbjct: 995  SEDIQKDKQQVQDLQKRLTQILDSVKSLESERSRLLSQIESQKLDL 1040



 Score = 65.7 bits (153), Expect = 1e-08
 Identities = 126/642 (19%), Positives = 272/642 (42%), Gaps = 66/642 (10%)

Query: 147  LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXX 206
            L N  K+ +N    L +K +  E    +LQ+  NE+D++   K                 
Sbjct: 914  LQNQTKDFNNVKRDLDLKHEEYEKVQYELQQVQNERDRL---KKDVMNLKNRIENLDQTV 970

Query: 207  XXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEE-ANKLLEAARF 265
                 E   QQ+ K  +          +EKQ + +DI+    ++  L++   ++L++ + 
Sbjct: 971  EKNRLE--IQQLNKQNQAL-------NNEKQSISEDIQKDKQQVQDLQKRLTQILDSVK- 1020

Query: 266  EISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEE------KGSLEIA 319
             +  E S+L  ++E               L KQ  E S E   ++E+         L+I+
Sbjct: 1021 SLESERSRLLSQIESQKLDLDKKKIEIDNLNKQVYEQSNERAQQLEKLMESQMNEKLKIS 1080

Query: 320  NMTELTK--KIEL------LEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLIS 371
             + E  +  KIE+      ++ L   I+  +++++     + T+   +    KK   L+S
Sbjct: 1081 ALNEQVQIYKIEIDQFKTKMQILEADIQARDEKIKILNKNIETQKITIDENDKKIESLVS 1140

Query: 372  RKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEK 431
             +S     ++ K   +QL +  LN   ++ + + EI +     + +  +   +EY   + 
Sbjct: 1141 EQSKVIAENEQK---NQLIT-NLNAAIEQALIECEIQQKNANSKKVELEEKQEEY---KH 1193

Query: 432  DTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELND 491
            +           G++ L    + E + + +   LI      + + E      Q +QELN 
Sbjct: 1194 ELERLQNEINELGRN-LATCKERERETNNKNVELI------QQIEEANHNLNQKEQELNQ 1246

Query: 492  EIKDVNVKDLIEKLKSAEEQITQLN---DEIDAANKNMIKVKSNHKLKLKQMQK-TIDNF 547
             ++++N+      + S E  + QLN    E D    N+     N   +L+ +Q+  + N 
Sbjct: 1247 IVEEMNLNK--NHINSNEMSLKQLNLDLKERDDYVSNLQDEVKNLTQQLEDLQRQDLQNQ 1304

Query: 548  SKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMEN 607
             ++ + N +I +L   L+ +  K  EL+ +  NL  +++D  S  + +  V K++IE  N
Sbjct: 1305 QEIENLNSQINKLKNNLNSMEDKNQELQSKTNNLLQNVIDLQSS-LQQLRVEKELIEQNN 1363

Query: 608  LAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKL----ADISQLQSDQVCSEIKSVH 663
              +   +++   + +K   ++     +++Y+++++      A    L   ++ ++ + + 
Sbjct: 1364 --QLLQESLQKEKEEKEIAIRCQDEQEKEYEKLKNSTICIDAHTQALDKLEIKNDQQKLE 1421

Query: 664  LEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDI--------MNKLQNYIQ 715
            +E+Q + L    ++L      ++  K+QL G     EN  + I        + K  +  Q
Sbjct: 1422 IEKQQEQLEQFAQQLITAETTIQSQKKQLDGHKIIQENYLKTISELSSKLNVEKKDSECQ 1481

Query: 716  ENMDLTDKLEKMS---AEKISELLAKINHEEQSKIQTQFGID 754
               +  +K+  +S   A+K  +LL  I+H ++  I +Q  I+
Sbjct: 1482 WEEEQDEKMISLSTYEAQKFRKLLKSIDHNKKIPIMSQKNIE 1523


>UniRef50_A0DDB5 Cluster: Chromosome undetermined scaffold_46, whole
            genome shotgun sequence; n=1; Paramecium tetraurelia|Rep:
            Chromosome undetermined scaffold_46, whole genome shotgun
            sequence - Paramecium tetraurelia
          Length = 1356

 Score =  133 bits (321), Expect = 4e-29
 Identities = 216/1152 (18%), Positives = 498/1152 (43%), Gaps = 81/1152 (7%)

Query: 474  DVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNH 533
            D++ I+  Q    ++  D+ +    +D +E   +A++   +          +  K  SN+
Sbjct: 122  DIDTISTAQSIADEQTTDKKQPGQTQDKLETESTAKKNSIESQQIKPLQIDDSSKQNSNN 181

Query: 534  KLKLKQMQKTIDNFSKVSD------SNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVD 587
              +L   ++ I+   +VS       S   I +L++EL  L +  AE++++  NL +  + 
Sbjct: 182  TQQLSDKEQAINLAKQVSPLAPSPLSQINIQQLSDELGELRKVNAEIKDQN-NLLIQEIQ 240

Query: 588  YDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADI 647
             +  ++++ ++ ++   ++   +  +  I+  + Q  D  +    L++   E E    ++
Sbjct: 241  KE--KLLKDELIQQFQNLKRQLDNSIN-INKYQDQILDYDKRAQQLKEALQESEISKENL 297

Query: 648  S-QLQSD-QVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKED 705
            S Q QS  Q+ S ++        +A    K+     +E L+ + +++Y   KD+ N +  
Sbjct: 298  SKQYQSTLQLYSGLQD-EFNTVKEAFLIEKENAKTFMEKLQ-ENQEIYKQ-KDVANQELT 354

Query: 706  IMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQ----FGIDAKIQERD 761
            I N  Q+ +Q  +D+  ++  ++ + +S  L +   E  ++I  Q      ++ +IQ++ 
Sbjct: 355  IKN--QSQLQRIIDVESQINLLNQQILS--LNRQKEESNNEILQQKDYIIQLEQQIQQQH 410

Query: 762  LYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLG-SYLQEKQKAYSEYTIQE 820
                ++  +      +I + ++ I  ++ +  + ++K +Q+   + Q+ ++   E  I  
Sbjct: 411  FQCSSLNDQKKSIDQQIQQYQQQIQELQSQLLNQQQKMNQMKIQFQQDSEQNRKESQINN 470

Query: 821  DELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEE-NQNLQISLSDMQQHYNAL 879
             +L +    + +++++     L+IE   +E  ++ +   E   Q +   +  ++Q   +L
Sbjct: 471  QKLQDYSQKISEYEKLQNDTQLKIEKMIEEHSQEIKNCSESIYQGVMPQIKQLKQEIASL 530

Query: 880  VEKANRTDLAESESTKYQTQLRDL-ESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIES 938
             E+AN   L + +  + + + + + E+ LK+  H  +  + Q +K I D+   F    E+
Sbjct: 531  -EQANLVQLEQLKVQESKNEEQTIRETQLKQSIHSSEAQLTQLQKLISDI---FG---ET 583

Query: 939  AIRDKKVLN-EKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQ 997
             I  K+ LN E +EK  E    L     +  + I  L   ++ LN       +K+  + +
Sbjct: 584  QILMKQFLNQENFEKETELPNILSKLHSQINSKINKLQSEIDLLNSQIQLQDEKYKDRSK 643

Query: 998  TQSPDYTEQYIN---EINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFT 1054
            +Q     +Q  N   EIN L   ++    +   L+ +  N + +   + +  E K  +F 
Sbjct: 644  SQQDCLIDQLSNKNCEINDLKLAIENLKNQNQFLHHENENIKKNVNEITNQLEQKQNEFQ 703

Query: 1055 T-KLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELK----------ETKLTFE 1103
              KL N E+ +Q  +KQL D +  N+ELQ+ ++  + + +E++          + K+   
Sbjct: 704  QLKLIN-EDNIQTQTKQLKDQQNLNQELQLKLKNFESESQEIQNSQQNKIKNADVKINEL 762

Query: 1104 MNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQ-SA 1162
            +N  K +  II+     + +   N+              K+QE++  I++ +  Q Q   
Sbjct: 763  LNELKQQENIINDQSHKLKE--GNMIIQDYTKKNQELLNKIQEQQYQIEQNTFQQSQYEI 820

Query: 1163 KLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLS----TVA 1218
            K     QE      Q+  LN +L        E++ +   + E +  EN+  +     T+ 
Sbjct: 821  KQKAIQQENAELQEQINLLNLQLQSFQEKIPEEVQRNAKEYEDIINENNQKIQEQQRTIK 880

Query: 1219 ELRSSISSAVDQ--RGFEIAELWKQHLAQREADFQKT-----EHELRVQLSAFESKYEQL 1271
            +L   I + +++  +  +  E   +   Q++ ++ +T     E EL++   AF  +  ++
Sbjct: 881  QLEQQIKAQMEEYKQNLDQQEQLHKKEFQKQNEYNQTTIQQLEEELKISKQAFLEQKIKI 940

Query: 1272 LDSVQSSTQEE-TNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDE 1330
             +S Q+  Q++  N    +E +  + N ++ + + L          + Q++  +   E +
Sbjct: 941  DESQQNQNQDQLQNSQSIIENLQLVNNTIKQQHQELELQHNNLKQHLVQVD--KKNQEQQ 998

Query: 1331 KVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSIL--NINEENAQLKKSSXXXXXXX 1388
            ++                  D   +N   ++    S L  ++ E   QL   +       
Sbjct: 999  QLLGQQQNQITTLQQKVKEMDGIIKNLEIEKNSISSKLTNDLQELQQQLFSENDEWQKEK 1058

Query: 1389 XXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRI 1448
                 +V D EA+   L   L+ K+ ++     E  I L  +N     ++Q++ E +K  
Sbjct: 1059 EIIQKQVEDLEAQNEGLKETLKEKEQQLLM-IQEQNIALKSQNQLLNEIQQKVQELDKEN 1117

Query: 1449 ED--LTYEKE-SEL-AILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQ 1504
            ++  L ++++  E+ +   L++    N  ++++++SE+ +   I EL  +I +     K 
Sbjct: 1118 KNNKLKWQQQVDEMNSNSNLQIQNLTNQIQSLEQQSEVYKAD-INELKRQINQKDDDIKL 1176

Query: 1505 VAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDT 1564
            + E +K L+ +   +N      E  E+ I  L  ++   Q     S  + Q  + F    
Sbjct: 1177 IEEKSK-LDNQYLNSNYNNKLREQDEL-IQQLQTDLQQFQQ----SEVEQQSLIKFLESA 1230

Query: 1565 KQGRDE-QLDNT 1575
            K+  ++ Q++N+
Sbjct: 1231 KENLEKLQIENS 1242



 Score =  127 bits (307), Expect = 2e-27
 Identities = 238/1201 (19%), Positives = 515/1201 (42%), Gaps = 111/1201 (9%)

Query: 305  EEKTEIEEKGSLEIANMTELTKK---IELLEHLNCQIRQTNKELENKLATMGTESKAVSS 361
            E+ T+ ++ G  +    TE T K   IE  +    QI  ++K+  N    +  + +A++ 
Sbjct: 135  EQTTDKKQPGQTQDKLETESTAKKNSIESQQIKPLQIDDSSKQNSNNTQQLSDKEQAINL 194

Query: 362  PSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTD--KKINKNEIAKLEMVIQSLNK 419
             +K+ SPL              SP SQ++ + L+ +    +K+N     +  ++IQ + K
Sbjct: 195  -AKQVSPLAP------------SPLSQINIQQLSDELGELRKVNAEIKDQNNLLIQEIQK 241

Query: 420  DLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIA 479
            + + K+ +I +                     L  + +      +L     + E++++  
Sbjct: 242  EKLLKDELIQQFQNLKRQLDNSININKYQDQILDYDKRAQQLKEALQESEISKENLSKQY 301

Query: 480  KVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVK--SNHKLKL 537
            +   QL   L DE   V    LIEK ++A+  + +L +     N+ + K K  +N +L +
Sbjct: 302  QSTLQLYSGLQDEFNTVKEAFLIEK-ENAKTFMEKLQE-----NQEIYKQKDVANQELTI 355

Query: 538  K---QMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHL-VDYDSGRM 593
            K   Q+Q+ ID  S+++  N++I+ L  +    + ++  L+++   +QL   +     + 
Sbjct: 356  KNQSQLQRIIDVESQINLLNQQILSLNRQKEESNNEI--LQQKDYIIQLEQQIQQQHFQC 413

Query: 594  IESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSD 653
               +  KK I+ +   +   + I  L+SQ  +  Q+++ ++ ++ +  ++    SQ+ + 
Sbjct: 414  SSLNDQKKSIDQQ--IQQYQQQIQELQSQLLNQQQKMNQMKIQFQQDSEQNRKESQINNQ 471

Query: 654  QVCSEIKSVHLEEQI--DALSASKKELALVIENLKLDKEQLY-GTIKDLENDKEDIMNKL 710
            ++    + +   E++  D     +K +    + +K   E +Y G +  ++  K++I +  
Sbjct: 472  KLQDYSQKISEYEKLQNDTQLKIEKMIEEHSQEIKNCSESIYQGVMPQIKQLKQEIASLE 531

Query: 711  Q-NYIQ-ENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQ------FGIDAKIQERDL 762
            Q N +Q E + + +   +    + ++L   I+  E    Q Q      FG    + ++ L
Sbjct: 532  QANLVQLEQLKVQESKNEEQTIRETQLKQSIHSSEAQLTQLQKLISDIFGETQILMKQFL 591

Query: 763  YIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYT-IQED 821
              EN E E ++  + + +L   I     +   L+ + D L S +Q + + Y + +  Q+D
Sbjct: 592  NQENFEKE-TELPNILSKLHSQI---NSKINKLQSEIDLLNSQIQLQDEKYKDRSKSQQD 647

Query: 822  ELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVE 881
             L+++L+     ++  E   L++  EN  L+ +NQ L  EN+N++ +++++         
Sbjct: 648  CLIDQLS-----NKNCEINDLKLAIEN--LKNQNQFLHHENENIKKNVNEITNQLEQKQN 700

Query: 882  KANRTDLAESESTKYQT-QLRD-------LESNLKRITHEHQTLIVQKKKEIEDLEIEFN 933
            +  +  L   ++ + QT QL+D       L+  LK    E Q +   ++ +I++ +++ N
Sbjct: 701  EFQQLKLINEDNIQTQTKQLKDQQNLNQELQLKLKNFESESQEIQNSQQNKIKNADVKIN 760

Query: 934  TQIESAIRDKKVLNEKYEKNIE---YVTQLEAQLQEYKNNIENLNMNVEE--LNKMNLEL 988
              +    + + ++N++  K  E    +     + QE  N I+     +E+    +   E+
Sbjct: 761  ELLNELKQQENIINDQSHKLKEGNMIIQDYTKKNQELLNKIQEQQYQIEQNTFQQSQYEI 820

Query: 989  IDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYES 1048
              K +Q++  +  +       +IN LN  L+   E+I    Q+  NA+  Y  ++++   
Sbjct: 821  KQKAIQQENAELQE-------QINLLNLQLQSFQEKIPEEVQR--NAK-EYEDIINENNQ 870

Query: 1049 KLAQFTTKLENMEEEMQRVS---KQLLDSKQ--HNEELQILVREQDDQIKELKETKLTFE 1103
            K+ +    ++ +E++++      KQ LD ++  H +E Q         I++L+E     +
Sbjct: 871  KIQEQQRTIKQLEQQIKAQMEEYKQNLDQQEQLHKKEFQKQNEYNQTTIQQLEEELKISK 930

Query: 1104 MNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQE--QS 1161
                + +  I  S      D   N              +K Q +E  +Q  ++ Q   Q 
Sbjct: 931  QAFLEQKIKIDESQQNQNQDQLQNSQSIIENLQLVNNTIKQQHQELELQHNNLKQHLVQV 990

Query: 1162 AKLNTELQECY-TKIIQLETLNTELTGHD--VVNQE-QINQLKSKL-EQLNTENDNLLST 1216
             K N E Q+    +  Q+ TL  ++   D  + N E + N + SKL   L      L S 
Sbjct: 991  DKKNQEQQQLLGQQQNQITTLQQKVKEMDGIIKNLEIEKNSISSKLTNDLQELQQQLFSE 1050

Query: 1217 VAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYE-QLLDSV 1275
              E +      + Q+  ++ +L  Q+   +E   +K +  L +Q      K + QLL+ +
Sbjct: 1051 NDEWQKE--KEIIQK--QVEDLEAQNEGLKETLKEKEQQLLMIQEQNIALKSQNQLLNEI 1106

Query: 1276 QSSTQE-----ETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDE 1330
            Q   QE     + NK+   +QV  + +   +    ++NL  +   +  Q E+ +++I + 
Sbjct: 1107 QQKVQELDKENKNNKLKWQQQVDEMNS---NSNLQIQNLTNQIQSLEQQSEVYKADINEL 1163

Query: 1331 KVAFXXXXXXXXXXXXXXXXDLRTENQSYKQM---QEQSILNINEENAQLKKSSXXXXXX 1387
            K                   D +  N +Y      Q++ I  +  +  Q ++S       
Sbjct: 1164 KRQINQKDDDIKLIEEKSKLDNQYLNSNYNNKLREQDELIQQLQTDLQQFQQSEVEQQSL 1223

Query: 1388 XXXXXXRVNDAEAKVLE---LTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEY 1444
                     + E   +E    T +++L + ++ +K  EY + +    +  EN+ Q+L + 
Sbjct: 1224 IKFLESAKENLEKLQIENSEYTQRIQLANDKMSEKIKEYEVKIISLKETIENLEQRLNQL 1283

Query: 1445 E 1445
            E
Sbjct: 1284 E 1284



 Score =  109 bits (263), Expect = 5e-22
 Identities = 218/1015 (21%), Positives = 440/1015 (43%), Gaps = 109/1015 (10%)

Query: 152  KEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXX 211
            K+KD A   L +K +     I+D++ +IN  +Q I + N+                    
Sbjct: 344  KQKDVANQELTIKNQSQLQRIIDVESQINLLNQQILSLNRQKEESNNEILQQKDYIIQLE 403

Query: 212  EDTKQQ------MTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLE-EANKLLEAAR 264
            +  +QQ      +   +++      +++ + Q L   + ++  +++ ++ +  +  E  R
Sbjct: 404  QQIQQQHFQCSSLNDQKKSIDQQIQQYQQQIQELQSQLLNQQQKMNQMKIQFQQDSEQNR 463

Query: 265  FEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTEL 324
             E  + + KL    ++              + K   E S E K   E      +  + +L
Sbjct: 464  KESQINNQKLQDYSQKISEYEKLQNDTQLKIEKMIEEHSQEIKNCSESIYQGVMPQIKQL 523

Query: 325  TKKIELLEHLN-CQIRQTN-KELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKM 382
             ++I  LE  N  Q+ Q   +E +N+  T+       S  S +      +K   +   + 
Sbjct: 524  KQEIASLEQANLVQLEQLKVQESKNEEQTIRETQLKQSIHSSEAQLTQLQKLISDIFGET 583

Query: 383  KSPWSQ-LSSETLNQDTD-----KKIN---KNEIAKLEMVIQSLNK--DLVDKEYVISEK 431
            +    Q L+ E   ++T+      K++    ++I KL+  I  LN    L D++Y    K
Sbjct: 584  QILMKQFLNQENFEKETELPNILSKLHSQINSKINKLQSEIDLLNSQIQLQDEKYKDRSK 643

Query: 432  DTXXXXXXXXXXGKDTLIAQLQLEHQQ-HMEGPSLIHVGTN-TEDVNEIAKVQEQLKQEL 489
             +           K+  I  L+L  +    +   L H   N  ++VNEI    EQ + E 
Sbjct: 644  -SQQDCLIDQLSNKNCEINDLKLAIENLKNQNQFLHHENENIKKNVNEITNQLEQKQNEF 702

Query: 490  ND--EIKDVNVKDLIEKLKSAE--EQITQL--------NDEIDAANKNMIK---VKSNHK 534
                 I + N++   ++LK  +   Q  QL        + EI  + +N IK   VK N  
Sbjct: 703  QQLKLINEDNIQTQTKQLKDQQNLNQELQLKLKNFESESQEIQNSQQNKIKNADVKINEL 762

Query: 535  L-KLKQMQKTI-DNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGR 592
            L +LKQ +  I D   K+ + N  I   T++   L  K+ E        Q + ++ ++ +
Sbjct: 763  LNELKQQENIINDQSHKLKEGNMIIQDYTKKNQELLNKIQE--------QQYQIEQNTFQ 814

Query: 593  MIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQEL-HILQQKYDEVEDKLADISQLQ 651
              + ++ +K I+ EN AE + + I+LL  Q     +++   +Q+   E ED + + +Q  
Sbjct: 815  QSQYEIKQKAIQQEN-AELQ-EQINLLNLQLQSFQEKIPEEVQRNAKEYEDIINENNQKI 872

Query: 652  SDQVCSEIKSVHLEEQIDALSASKKELALVIENL---KLDKEQLYG--TIKDLENDKEDI 706
             +Q    IK   LE+QI A     K+     E L   +  K+  Y   TI+ LE   E++
Sbjct: 873  QEQQ-RTIK--QLEQQIKAQMEEYKQNLDQQEQLHKKEFQKQNEYNQTTIQQLE---EEL 926

Query: 707  MNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIEN 766
                Q ++++ + + +  +  + +++    + I  E    +     I  + QE +L   N
Sbjct: 927  KISKQAFLEQKIKIDESQQNQNQDQLQNSQSII--ENLQLVNNT--IKQQHQELELQHNN 982

Query: 767  IESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQ----EKQKAYSEYTIQEDE 822
            ++  L +   +    ++ +   +++  +L++K  ++   ++    EK    S+ T    E
Sbjct: 983  LKQHLVQVDKKNQEQQQLLGQQQNQITTLQQKVKEMDGIIKNLEIEKNSISSKLTNDLQE 1042

Query: 823  LVNRLAVLMD----HDRVVEKQLLEIEHENKEL-----QKKNQILLEENQNLQISLSDMQ 873
            L  +L    D       +++KQ+ ++E +N+ L     +K+ Q+L+ + QN  I+L    
Sbjct: 1043 LQQQLFSENDEWQKEKEIIQKQVEDLEAQNEGLKETLKEKEQQLLMIQEQN--IALKSQN 1100

Query: 874  QHYNALVEKANRTDLA-ESESTKYQTQLRDLESN----LKRITHEHQTLIVQK---KKEI 925
            Q  N + +K    D   ++   K+Q Q+ ++ SN    ++ +T++ Q+L  Q    K +I
Sbjct: 1101 QLLNEIQQKVQELDKENKNNKLKWQQQVDEMNSNSNLQIQNLTNQIQSLEQQSEVYKADI 1160

Query: 926  EDLEIEFNTQ------IESAIR-DKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNV 978
             +L+ + N +      IE   + D + LN  Y   +    +L  QLQ      +   +  
Sbjct: 1161 NELKRQINQKDDDIKLIEEKSKLDNQYLNSNYNNKLREQDELIQQLQTDLQQFQQSEVEQ 1220

Query: 979  EELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVS 1038
            + L K  LE   ++++K Q ++ +YT++     +K++  +K+ + +II+L + I N    
Sbjct: 1221 QSLIKF-LESAKENLEKLQIENSEYTQRIQLANDKMSEKIKEYEVKIISLKETIEN---- 1275

Query: 1039 YMSMVSDYESKLAQFTTKLENMEEE-MQRVSKQLLDSKQHNEELQILVREQDDQI 1092
                    E +L Q   +  N +++ +Q V + L+++K   E  Q++ + QD+ I
Sbjct: 1276 -------LEQRLNQLEFENSNHKQQVLQPVVENLIENKSQKESNQLIEQLQDEII 1323



 Score =  106 bits (254), Expect = 6e-21
 Identities = 206/993 (20%), Positives = 423/993 (42%), Gaps = 90/993 (9%)

Query: 642  DKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLEN 701
            D ++    +  +Q   + +    +++++  S +KK     IE+ ++   Q+  + K   N
Sbjct: 124  DTISTAQSIADEQTTDKKQPGQTQDKLETESTAKKNS---IESQQIKPLQIDDSSKQNSN 180

Query: 702  DKEDIMNKLQ--NYIQENMDLTDK-LEKMSAEKISELLAKINH-EEQSKIQTQFGIDAKI 757
            + + + +K Q  N  ++   L    L +++ +++S+ L ++     + K Q    I  +I
Sbjct: 181  NTQQLSDKEQAINLAKQVSPLAPSPLSQINIQQLSDELGELRKVNAEIKDQNNLLIQ-EI 239

Query: 758  QERDLYIENIESELSKYKSRICRLEESIAV--MEDRRYSLERKADQLGSYLQEKQKAYSE 815
            Q+  L  + +  +    K +   L+ SI +   +D+    +++A QL   LQE + +   
Sbjct: 240  QKEKLLKDELIQQFQNLKRQ---LDNSININKYQDQILDYDKRAQQLKEALQESEISKEN 296

Query: 816  YTIQEDELVNRLAVLMDHDRVVEKQLLEIEHEN-KELQKKNQILLEENQNLQISLSDMQQ 874
             + Q    +   + L D    V++  L IE EN K   +K    L+ENQ +        Q
Sbjct: 297  LSKQYQSTLQLYSGLQDEFNTVKEAFL-IEKENAKTFMEK----LQENQEIYKQKDVANQ 351

Query: 875  HYNALVEKANRTDLAESESTKYQTQLRDLES-NLKRITHEHQTLIVQKKKEIEDLEIEFN 933
                     N++ L      + Q  L + +  +L R   E    I+Q+K  I  LE +  
Sbjct: 352  ELTI----KNQSQLQRIIDVESQINLLNQQILSLNRQKEESNNEILQQKDYIIQLEQQIQ 407

Query: 934  TQIE--SAIRD-KKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELID 990
             Q    S++ D KK ++++ ++  + + +L++QL   +  +  + +  ++ ++ N +  +
Sbjct: 408  QQHFQCSSLNDQKKSIDQQIQQYQQQIQELQSQLLNQQQKMNQMKIQFQQDSEQNRK--E 465

Query: 991  KHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALN-QKINNAQVSYMSMVSDYESK 1049
              +  Q+ Q  DY+++ I+E  KL    + K E++I  + Q+I N   S    V     +
Sbjct: 466  SQINNQKLQ--DYSQK-ISEYEKLQNDTQLKIEKMIEEHSQEIKNCSESIYQGVMPQIKQ 522

Query: 1050 LAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKT 1109
            L Q    LE     +Q    ++ +SK   + ++    +Q     E + T+L   ++    
Sbjct: 523  LKQEIASLEQANL-VQLEQLKVQESKNEEQTIRETQLKQSIHSSEAQLTQLQKLISDIFG 581

Query: 1110 EGMIISSTI---EPMSDDANNVDXXXXXXXXXXXXL-KVQEEEEFIQERSVLQEQSAKLN 1165
            E  I+       E    +    +            + K+Q E + +  +  LQ++  K  
Sbjct: 582  ETQILMKQFLNQENFEKETELPNILSKLHSQINSKINKLQSEIDLLNSQIQLQDEKYKDR 641

Query: 1166 TELQE-CYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSI 1224
            ++ Q+ C   I QL   N E+    +     I  LK++ + L+ EN+N+   V E+ + +
Sbjct: 642  SKSQQDCL--IDQLSNKNCEINDLKLA----IENLKNQNQFLHHENENIKKNVNEITNQL 695

Query: 1225 SSAVDQRGFEIAELWKQHLAQREA----DFQKTEHELRVQLSAFESKYEQLLDSVQSSTQ 1280
                 Q  F+  +L  +   Q +     D Q    EL+++L  FES+ +++ +S Q+  +
Sbjct: 696  EQK--QNEFQQLKLINEDNIQTQTKQLKDQQNLNQELQLKLKNFESESQEIQNSQQNKIK 753

Query: 1281 EETNKI-VTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXX 1339
                KI   + ++   +N + D+   L+       D   + + L ++I++++        
Sbjct: 754  NADVKINELLNELKQQENIINDQSHKLKEGNMIIQDYTKKNQELLNKIQEQQYQIEQNTF 813

Query: 1340 XXXXXXXXXXXDLRTENQSYKQMQEQ-SILNINEENAQLKKSSXXXXXXXXXXXXRVNDA 1398
                        ++ EN    ++QEQ ++LN+  ++ Q +K               +N+ 
Sbjct: 814  QQSQYEIKQKA-IQQENA---ELQEQINLLNLQLQSFQ-EKIPEEVQRNAKEYEDIINEN 868

Query: 1399 EAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKR-IEDLTYE-KE 1456
              K+ E    ++  + +I  +  EY   L Q+    +   Q+  EY +  I+ L  E K 
Sbjct: 869  NQKIQEQQRTIKQLEQQIKAQMEEYKQNLDQQEQLHKKEFQKQNEYNQTTIQQLEEELKI 928

Query: 1457 SELAILRLKM-----HENANHYETMQKESEIERVKLI--------EELNVKITES----V 1499
            S+ A L  K+      +N N  +    +S IE ++L+        +EL ++        V
Sbjct: 929  SKQAFLEQKIKIDESQQNQNQDQLQNSQSIIENLQLVNNTIKQQHQELELQHNNLKQHLV 988

Query: 1500 SLNKQVAELNKALEEEV-------AKTNEMQTALENQEIEIVTLNDEITN----LQNMVR 1548
             ++K+  E  + L ++         K  EM   ++N EIE  +++ ++TN    LQ  + 
Sbjct: 989  QVDKKNQEQQQLLGQQQNQITTLQQKVKEMDGIIKNLEIEKNSISSKLTNDLQELQQQLF 1048

Query: 1549 ASSSKIQKHVSFASDTKQGRDEQLDNTMNKELL 1581
            + + + QK        KQ  D +  N   KE L
Sbjct: 1049 SENDEWQKEKEIIQ--KQVEDLEAQNEGLKETL 1079



 Score = 99.1 bits (236), Expect = 9e-19
 Identities = 205/995 (20%), Positives = 426/995 (42%), Gaps = 112/995 (11%)

Query: 144  VTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXX 203
            +  L   I+++    S L  + K ++  I   Q++I E    +  + +            
Sbjct: 399  IIQLEQQIQQQHFQCSSLNDQKKSIDQQIQQYQQQIQELQSQLLNQQQKMNQMKIQFQQD 458

Query: 204  XXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEA-----NK 258
                    +   Q++    +     E    D + ++ K IE     I +  E+       
Sbjct: 459  SEQNRKESQINNQKLQDYSQKISEYEKLQNDTQLKIEKMIEEHSQEIKNCSESIYQGVMP 518

Query: 259  LLEAARFEI-SLEHSKLAQELEQXXXXXXXXXXXXX--XLAKQSIEPSCEEKTEIEEKGS 315
             ++  + EI SLE + L Q LEQ                  KQSI  S  + T++++  S
Sbjct: 519  QIKQLKQEIASLEQANLVQ-LEQLKVQESKNEEQTIRETQLKQSIHSSEAQLTQLQKLIS 577

Query: 316  LEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSG 375
             +I   T++  K    + LN +  +   EL N L+ +   S+  S  +K  S +    S 
Sbjct: 578  -DIFGETQILMK----QFLNQENFEKETELPNILSKL--HSQINSKINKLQSEIDLLNSQ 630

Query: 376  RNTASKMKSPWSQLSSETLNQDTDKKINKN-EIAKLEMVIQSLNKDLVDKEYVISEKDTX 434
                 +     S+   + L    D+  NKN EI  L++ I++L       +++  E +  
Sbjct: 631  IQLQDEKYKDRSKSQQDCL---IDQLSNKNCEINDLKLAIENLKNQ---NQFLHHENENI 684

Query: 435  XXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQEL-NDEI 493
                          + Q Q E QQ ++  +  ++ T T+ + +   + ++L+ +L N E 
Sbjct: 685  KKNVNEIT----NQLEQKQNEFQQ-LKLINEDNIQTQTKQLKDQQNLNQELQLKLKNFES 739

Query: 494  KDVNVKDLIE-KLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQM------QKTIDN 546
            +   +++  + K+K+A+ +I +L +E+    +N+I  +S HKLK   M      +K  + 
Sbjct: 740  ESQEIQNSQQNKIKNADVKINELLNELKQ-QENIINDQS-HKLKEGNMIIQDYTKKNQEL 797

Query: 547  FSKVSDSNKEIVRLT--EELHHLSQKV-----AELEEEKGNLQLHLVDYDSGRMIESDVY 599
             +K+ +   +I + T  +  + + QK      AEL+E+   L L L  +     I  +V 
Sbjct: 798  LNKIQEQQYQIEQNTFQQSQYEIKQKAIQQENAELQEQINLLNLQLQSFQE--KIPEEVQ 855

Query: 600  KKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEI 659
            +   E E++     + I   +     L Q++    ++Y +  D+   + + +  Q  +E 
Sbjct: 856  RNAKEYEDIINENNQKIQEQQRTIKQLEQQIKAQMEEYKQNLDQQEQLHKKEF-QKQNEY 914

Query: 660  KSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMD 719
                +++  + L  SK+  A + + +K+D+ Q        +N  +D +   Q+ I EN+ 
Sbjct: 915  NQTTIQQLEEELKISKQ--AFLEQKIKIDESQ--------QNQNQDQLQNSQSII-ENLQ 963

Query: 720  LTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRIC 779
            L +   K   +   EL  + N+ +Q  +Q    +D K QE+   +   +++++  + ++ 
Sbjct: 964  LVNNTIKQQHQ---ELELQHNNLKQHLVQ----VDKKNQEQQQLLGQQQNQITTLQQKVK 1016

Query: 780  RLEESIAVMEDRRYSLERKADQLGSYLQE-KQKAYSEYTIQEDELVNRLAVLMDHDRVVE 838
             ++  I  +E  + S+  K   L + LQE +Q+ +SE     DE             +++
Sbjct: 1017 EMDGIIKNLEIEKNSISSK---LTNDLQELQQQLFSE----NDEW-------QKEKEIIQ 1062

Query: 839  KQLLEIEHENKEL-----QKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLA-ESE 892
            KQ+ ++E +N+ L     +K+ Q+L+ + QN  I+L    Q  N + +K    D   ++ 
Sbjct: 1063 KQVEDLEAQNEGLKETLKEKEQQLLMIQEQN--IALKSQNQLLNEIQQKVQELDKENKNN 1120

Query: 893  STKYQTQLRDLESN----LKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNE 948
              K+Q Q+ ++ SN    ++ +T++ Q+L  Q +    D+  E   QI     D K++ E
Sbjct: 1121 KLKWQQQVDEMNSNSNLQIQNLTNQIQSLEQQSEVYKADIN-ELKRQINQKDDDIKLIEE 1179

Query: 949  KYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYI 1008
            K + + +Y+         Y N +   +  +++L + +L+   +   +QQ+    + E   
Sbjct: 1180 KSKLDNQYLNS------NYNNKLREQDELIQQL-QTDLQQFQQSEVEQQSLIK-FLESAK 1231

Query: 1009 NEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVS 1068
              + KL     +  + I   N K++         + +YE K+      +EN+E+ + ++ 
Sbjct: 1232 ENLEKLQIENSEYTQRIQLANDKMSEK-------IKEYEVKIISLKETIENLEQRLNQLE 1284

Query: 1069 KQLLDSKQHNEELQILVREQDDQIKELKETKLTFE 1103
                ++  H +++   V E   + K  KE+    E
Sbjct: 1285 ---FENSNHKQQVLQPVVENLIENKSQKESNQLIE 1316



 Score = 41.9 bits (94), Expect = 0.14
 Identities = 69/369 (18%), Positives = 143/369 (38%), Gaps = 33/369 (8%)

Query: 147  LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQII-EAKNKATTXXXXXXXXXXX 205
            ++NTIK++   L +    +K     ++ + +K  E+ Q++ + +N+ TT           
Sbjct: 965  VNNTIKQQHQELELQHNNLK---QHLVQVDKKNQEQQQLLGQQQNQITTLQQKVKEMDGI 1021

Query: 206  XXXXXXEDTK------QQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKL 259
                  E           + ++Q+   +   EW+ EK+ + K +E  + +   L+E   L
Sbjct: 1022 IKNLEIEKNSISSKLTNDLQELQQQLFSENDEWQKEKEIIQKQVEDLEAQNEGLKET--L 1079

Query: 260  LEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIA 319
             E  +  + ++   +A  L+               L K++     + + +++E  S    
Sbjct: 1080 KEKEQQLLMIQEQNIA--LKSQNQLLNEIQQKVQELDKENKNNKLKWQQQVDEMNSNSNL 1137

Query: 320  NMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTA 379
             +  LT +I+ LE  +   +    EL+ ++     + K +   SK  +  ++  S  N  
Sbjct: 1138 QIQNLTNQIQSLEQQSEVYKADINELKRQINQKDDDIKLIEEKSKLDNQYLN--SNYNNK 1195

Query: 380  SKMKSPWSQLSSETLNQDTDKKINKNEIAK-LEMVIQSLNK-DLVDKEYV---------- 427
             + +    Q     L Q    ++ +  + K LE   ++L K  + + EY           
Sbjct: 1196 LREQDELIQQLQTDLQQFQQSEVEQQSLIKFLESAKENLEKLQIENSEYTQRIQLANDKM 1255

Query: 428  ---ISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQ 484
               I E +             +  + QL+ E+  H +   L  V  N  + N+  K   Q
Sbjct: 1256 SEKIKEYEVKIISLKETIENLEQRLNQLEFENSNHKQ-QVLQPVVENLIE-NKSQKESNQ 1313

Query: 485  LKQELNDEI 493
            L ++L DEI
Sbjct: 1314 LIEQLQDEI 1322


>UniRef50_A0CZE8 Cluster: Chromosome undetermined scaffold_32, whole
            genome shotgun sequence; n=3; Paramecium tetraurelia|Rep:
            Chromosome undetermined scaffold_32, whole genome shotgun
            sequence - Paramecium tetraurelia
          Length = 1064

 Score =  133 bits (321), Expect = 4e-29
 Identities = 202/960 (21%), Positives = 416/960 (43%), Gaps = 88/960 (9%)

Query: 623  KFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVI 682
            +F+ ++EL  + ++ +    +L    + Q+ ++ +      +E+ I  +   + EL    
Sbjct: 99   QFNRIKELEGVNEQQEIRIRELQTKLESQTTEISNYKLKSEIEKHIIRIKQLESELNEYK 158

Query: 683  ENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQE-NMDLTD------KLEKMSAEKISEL 735
              L    + L G +K+ E   +D   +L N+  + N D T+      +L  +  +K  EL
Sbjct: 159  SKLGSVDQSLAGRLKEAERKLQDSDKELTNWKNKYNTDKTNWDNEIRRLNDLLTQKQKEL 218

Query: 736  LAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSL 795
                N++ ++  Q Q     ++++ +  I   ES++S YKS I RL +   ++ +R   +
Sbjct: 219  DDYKNNQGKNYEQLQ----QQLRQYETKIREYESQISTYKSDIDRLNK---LLLERNSEI 271

Query: 796  ERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQK-K 854
            +R  ++L + LQE     S++T  +++  N +     ++  +      +++ +++L   K
Sbjct: 272  DRLKNELKTRLQELDDWRSKFTNLQNQF-NTMK--SQYESKINDLTNTLQNRDRDLNDWK 328

Query: 855  NQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEH 914
            N+    E Q   +  S      + + +  NR    +S+  +  TQLRD ++ ++ +  + 
Sbjct: 329  NKYAKLEGQFNNLG-SLQSGSESKITDLQNRLSQLQSDFDRQATQLRDRDAQIQALKEKL 387

Query: 915  QTLIVQK---KKEIEDLEIEFNTQI-ESAIRDKKVLNEKYEKNI--EYVTQLEAQLQEYK 968
            Q L         +++DL+  +N  + E+     ++ N K E +   + + Q   QL+ Y+
Sbjct: 388  QRLEQDNFNLNNQLQDLQSRYNNLLKENEKLQNELRNRKNELDFMKQQLQQANDQLKRYE 447

Query: 969  NNIENLNMNVEELNK--MNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEII 1026
            + I  LN  + E     M L+   + +++Q       +   + E+   N  L+ KD++I 
Sbjct: 448  DQINQLNEQIMECKDQIMALQNSKEMLERQLQDLYSKSNDNVGELKSANDQLEGKDKDIA 507

Query: 1027 ALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVR 1086
             L  ++N  QV    M    ES ++    +L N  +E+QR+  Q     Q   ELQ    
Sbjct: 508  DLRDQLNQFQVDRQIM----ESMISSLNNQLANKNDEIQRLLAQNKLRLQQLLELQSRYA 563

Query: 1087 EQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANN--VDXXXXXXXXXXXXLKV 1144
            + D  + +LK  +L  +  I +       S ++ + DD                    K+
Sbjct: 564  QLDYLLSDLKGVELQNKQLIARI------SELQQLVDDLKRKLAQQELQLLQSKSNEFKI 617

Query: 1145 QEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLE 1204
            QE E  I+E   L ++  +LN  L +   K+ + + LN ++    +  + +IN+LK+ LE
Sbjct: 618  QELENIIKE---LAKEIQRLNEFLNQ---KLSENDKLNMQI----ISMENEINKLKN-LE 666

Query: 1205 QLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAF 1264
             L  E +  L T  +  + +   +D R  E+ E W+   ++ E    + + +L  +   F
Sbjct: 667  PLLRELEKKLQTHLDDIARLKQLLDSRTNELNE-WRLKYSKLEPVIDE-KRQLEEKNRLF 724

Query: 1265 ESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNK-----------LQDKEEHLRNLQEKY 1313
            E++ + L   ++  T++   K + ++Q+  + N+           +   E  L NLQ  Y
Sbjct: 725  ENRIQGLHQDIERLTKQLRQKQLDIDQLNWILNQTEGLLRNRDDSINSLETRLNNLQRSY 784

Query: 1314 ADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEE 1373
             D   Q  +   +I+ +                    DL   N++ K++  Q   N N++
Sbjct: 785  -DNERQKTLNFEQIQSQLQQAVDKINQLETQIKGLQNDL---NRAKKEVTYQQ--NENDQ 838

Query: 1374 NAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRND- 1432
              Q    S            R  + E ++ +   ++E    +   K   Y   L Q N  
Sbjct: 839  MRQQIAKSEITILDLKQNEARFKEVENRLNQSQKEVEKLTRQFNDKLQAYE-ELKQNNGL 897

Query: 1433 ---EFENVRQQLVEYEKRIEDLTYEKESELAILR---LKMHENANHYE--------TM-Q 1477
               +++N++QQ  E  +R+  L  +  ++  IL+   L++  N   Y+        T+ Q
Sbjct: 898  LDTKYKNLQQQYQELLQRLNQLE-QINNQYQILKAKNLELENNNKQYKIDQDRLNSTLNQ 956

Query: 1478 KESEIERVK-LIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTL 1536
            K  E+  ++ L+ +L  KI +     ++ A +    E+E+ K++E+Q  +  QE ++  L
Sbjct: 957  KLQELNELQNLLPQLEDKIHQLTPFEEKYAIVQPKYEQELNKSDELQRKIRGQEQQLQEL 1016



 Score =  118 bits (285), Expect = 1e-24
 Identities = 177/818 (21%), Positives = 366/818 (44%), Gaps = 103/818 (12%)

Query: 331  LEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLS 390
            ++ LN  + + N E++     + T  + +     K + L  +       S+ +S  + L+
Sbjct: 257  IDRLNKLLLERNSEIDRLKNELKTRLQELDDWRSKFTNL--QNQFNTMKSQYESKINDLT 314

Query: 391  SETLNQDTDKKINKNEIAKLEMVIQSLNK-------DLVDKEYVISEKDTXXXXXXXXXX 443
            +   N+D D    KN+ AKLE    +L          + D +  +S+  +          
Sbjct: 315  NTLQNRDRDLNDWKNKYAKLEGQFNNLGSLQSGSESKITDLQNRLSQLQSDFDRQATQLR 374

Query: 444  GKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDV----NEIAKVQEQLKQELNDEIKDVN-- 497
             +D  I  L+ E  Q +E  +  ++    +D+    N + K  E+L+ EL +   +++  
Sbjct: 375  DRDAQIQALK-EKLQRLEQDNF-NLNNQLQDLQSRYNNLLKENEKLQNELRNRKNELDFM 432

Query: 498  ---VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSN 554
               ++   ++LK  E+QI QLN++I      ++ ++++ ++  +Q+Q   D +SK +D+ 
Sbjct: 433  KQQLQQANDQLKRYEDQINQLNEQIMECKDQIMALQNSKEMLERQLQ---DLYSKSNDNV 489

Query: 555  KEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMEN--LAETR 612
             E+    ++L    + +A+L ++    Q           ++  + + MI   N  LA   
Sbjct: 490  GELKSANDQLEGKDKDIADLRDQLNQFQ-----------VDRQIMESMISSLNNQLANKN 538

Query: 613  LKAISLLESQKFDLVQELHILQQKYDEVEDKLADIS--QLQSDQVCSEIKSVHLEEQIDA 670
             +   LL   K  L Q+L  LQ +Y +++  L+D+   +LQ+ Q+ + I    L++ +D 
Sbjct: 539  DEIQRLLAQNKLRL-QQLLELQSRYAQLDYLLSDLKGVELQNKQLIARISE--LQQLVDD 595

Query: 671  LSA--SKKELALVIENLKLDK-EQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKM 727
            L    +++EL L+       K ++L   IK+L  + + +   L   + EN  L  ++  M
Sbjct: 596  LKRKLAQQELQLLQSKSNEFKIQELENIIKELAKEIQRLNEFLNQKLSENDKLNMQIISM 655

Query: 728  SAEKISEL--LAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLE--- 782
              E I++L  L  +  E + K+QT     A++++    +++  +EL++++ +  +LE   
Sbjct: 656  ENE-INKLKNLEPLLRELEKKLQTHLDDIARLKQ---LLDSRTNELNEWRLKYSKLEPVI 711

Query: 783  -------ESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDR 835
                   E   + E+R   L +  ++L   L++KQ    +     ++    L    D   
Sbjct: 712  DEKRQLEEKNRLFENRIQGLHQDIERLTKQLRQKQLDIDQLNWILNQTEGLLRNRDDSIN 771

Query: 836  VVEKQL--LEIEHENK--------ELQKKNQILLEENQNLQISLSDMQQHYNALVEKA-- 883
             +E +L  L+  ++N+        ++Q + Q  +++   L+  +  +Q   N   ++   
Sbjct: 772  SLETRLNNLQRSYDNERQKTLNFEQIQSQLQQAVDKINQLETQIKGLQNDLNRAKKEVTY 831

Query: 884  --NRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIR 941
              N  D    +  K +  + DL+ N  R   E +  + Q +KE+E L  +FN +++ A  
Sbjct: 832  QQNENDQMRQQIAKSEITILDLKQNEARFK-EVENRLNQSQKEVEKLTRQFNDKLQ-AYE 889

Query: 942  DKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSP 1001
            + K  N   +   + + Q   +L +  N +E +N   + L   NLEL + +         
Sbjct: 890  ELKQNNGLLDTKYKNLQQQYQELLQRLNQLEQINNQYQILKAKNLELENNN--------- 940

Query: 1002 DYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENME 1061
               +QY  + ++LN+ L QK +E+       N  Q    +++   E K+ Q T      E
Sbjct: 941  ---KQYKIDQDRLNSTLNQKLQEL-------NELQ----NLLPQLEDKIHQLTP----FE 982

Query: 1062 EEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETK 1099
            E+   V  +       ++ELQ  +R Q+ Q++EL++ K
Sbjct: 983  EKYAIVQPKYEQELNKSDELQRKIRGQEQQLQELEKVK 1020



 Score =  107 bits (258), Expect = 2e-21
 Identities = 200/1014 (19%), Positives = 427/1014 (42%), Gaps = 94/1014 (9%)

Query: 469  GTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEK----LKSAEEQITQLNDEIDAANK 524
            G N +    I ++Q +L+ +   EI +  +K  IEK    +K  E ++ +   ++ + ++
Sbjct: 108  GVNEQQEIRIRELQTKLESQTT-EISNYKLKSEIEKHIIRIKQLESELNEYKSKLGSVDQ 166

Query: 525  NMIKVKSNHKLKLKQMQKTIDNFSKVSDSNK-----EIVRLTEELHHLSQKVAELEEEKG 579
            ++       + KL+   K + N+    +++K     EI RL + L   +QK  EL++ K 
Sbjct: 167  SLAGRLKEAERKLQDSDKELTNWKNKYNTDKTNWDNEIRRLNDLL---TQKQKELDDYKN 223

Query: 580  NLQLHLVDYDSG-RMIESDV--YKKMIEMENLAETRLKAISLLESQKFD-LVQELHILQQ 635
            N   +        R  E+ +  Y+  I        RL  + L  + + D L  EL    Q
Sbjct: 224  NQGKNYEQLQQQLRQYETKIREYESQISTYKSDIDRLNKLLLERNSEIDRLKNELKTRLQ 283

Query: 636  KYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGT 695
            + D+   K  ++ Q Q + + S+ +S  + +  + L    ++L    +N     E  +  
Sbjct: 284  ELDDWRSKFTNL-QNQFNTMKSQYES-KINDLTNTLQNRDRDLN-DWKNKYAKLEGQFNN 340

Query: 696  IKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDA 755
            +  L++  E  +  LQN + +     D+      ++ +++ A +  + Q   Q  F ++ 
Sbjct: 341  LGSLQSGSESKITDLQNRLSQLQSDFDRQATQLRDRDAQIQA-LKEKLQRLEQDNFNLNN 399

Query: 756  KIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSE 815
            ++Q+      N+  E  K ++ +   +  +  M+ +   L++  DQL  Y    +   ++
Sbjct: 400  QLQDLQSRYNNLLKENEKLQNELRNRKNELDFMKQQ---LQQANDQLKRY----EDQINQ 452

Query: 816  YTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQH 875
               Q  E  +++  L +   ++E+QL ++  ++ +   + +   ++ +     ++D++  
Sbjct: 453  LNEQIMECKDQIMALQNSKEMLERQLQDLYSKSNDNVGELKSANDQLEGKDKDIADLRDQ 512

Query: 876  YNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDL-EIEFN- 933
             N       + D    ES      +  L + L     E Q L+ Q K  ++ L E++   
Sbjct: 513  LNQF-----QVDRQIMES-----MISSLNNQLANKNDEIQRLLAQNKLRLQQLLELQSRY 562

Query: 934  TQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHV 993
             Q++  + D K +  + ++ I  +++L+  + + K  +       +EL  +  +  +  +
Sbjct: 563  AQLDYLLSDLKGVELQNKQLIARISELQQLVDDLKRKLAQ-----QELQLLQSKSNEFKI 617

Query: 994  QKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQF 1053
            Q+ +    +  ++   EI +LN  L QK  E   LN +I + + + ++ + + E  L + 
Sbjct: 618  QELE----NIIKELAKEIQRLNEFLNQKLSENDKLNMQIISME-NEINKLKNLEPLLREL 672

Query: 1054 TTKLENMEEEMQRVSKQLLDSKQHN-EELQILVREQD---DQIKELKETKLTFEMNIPKT 1109
              KL+   +++ R+ KQLLDS+ +   E ++   + +   D+ ++L+E    FE  I   
Sbjct: 673  EKKLQTHLDDIARL-KQLLDSRTNELNEWRLKYSKLEPVIDEKRQLEEKNRLFENRIQGL 731

Query: 1110 EGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQ 1169
               I   T + +     ++D            L+ +++         +     +LN  LQ
Sbjct: 732  HQDIERLT-KQLRQKQLDIDQLNWILNQTEGLLRNRDDS--------INSLETRLNN-LQ 781

Query: 1170 ECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSIS---S 1226
              Y    Q +TLN E        Q Q+ Q   K+ QL T+   L + +   +  ++   +
Sbjct: 782  RSYDNERQ-KTLNFEQI------QSQLQQAVDKINQLETQIKGLQNDLNRAKKEVTYQQN 834

Query: 1227 AVDQRGFEIA--ELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETN 1284
              DQ   +IA  E+    L Q EA F++ E+ L       E    Q  D +Q+  + + N
Sbjct: 835  ENDQMRQQIAKSEITILDLKQNEARFKEVENRLNQSQKEVEKLTRQFNDKLQAYEELKQN 894

Query: 1285 KIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRS---EIEDEKVAFXXXXXXX 1341
              +   +  +LQ + Q+  + L  L++    + NQ +IL++   E+E+    +       
Sbjct: 895  NGLLDTKYKNLQQQYQELLQRLNQLEQ----INNQYQILKAKNLELENNNKQYKIDQDRL 950

Query: 1342 XXXXXXXXXDLRTENQSYKQMQEQ--SILNINEENAQLKKSSXXXXXXXXXXXXRVNDAE 1399
                     +L        Q++++   +    E+ A ++               ++   E
Sbjct: 951  NSTLNQKLQELNELQNLLPQLEDKIHQLTPFEEKYAIVQPKYEQELNKSDELQRKIRGQE 1010

Query: 1400 AKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTY 1453
             ++ EL      K  +I Q   + T+ LT    E E +RQQ  + +  I+DL +
Sbjct: 1011 QQLQELE-----KVKKIVQ---DQTVMLTVLFGECEGLRQQCTDKDGEIQDLRF 1056



 Score = 82.2 bits (194), Expect = 1e-13
 Identities = 135/655 (20%), Positives = 291/655 (44%), Gaps = 63/655 (9%)

Query: 377  NTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXX 436
            N    ++S ++ L  E      + +  KNE+  ++  +Q  N  L  K Y    +D    
Sbjct: 399  NQLQDLQSRYNNLLKENEKLQNELRNRKNELDFMKQQLQQANDQL--KRY----EDQINQ 452

Query: 437  XXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTED-VNEIAKVQEQLKQELND--EI 493
                    KD ++A   L++ + M    L  + + + D V E+    +QL+ +  D  ++
Sbjct: 453  LNEQIMECKDQIMA---LQNSKEMLERQLQDLYSKSNDNVGELKSANDQLEGKDKDIADL 509

Query: 494  KDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDS 553
            +D   +  +++ +  E  I+ LN+++   N  + ++ + +KL+L+Q+ +    ++++   
Sbjct: 510  RDQLNQFQVDR-QIMESMISSLNNQLANKNDEIQRLLAQNKLRLQQLLELQSRYAQLDYL 568

Query: 554  NKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRL 613
              ++  +  +   L  +++EL++   +L+  L   +   +       K+ E+EN+ +   
Sbjct: 569  LSDLKGVELQNKQLIARISELQQLVDDLKRKLAQQELQLLQSKSNEFKIQELENIIKELA 628

Query: 614  KAI---------SLLESQKFDL--------VQELHILQQKYDEVEDKLA----DISQLQS 652
            K I          L E+ K ++        + +L  L+    E+E KL     DI++L+ 
Sbjct: 629  KEIQRLNEFLNQKLSENDKLNMQIISMENEINKLKNLEPLLRELEKKLQTHLDDIARLKQ 688

Query: 653  --DQVCSEIKSVHLE-EQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNK 709
              D   +E+    L+  +++ +   K++L    E  +L + ++ G  +D+E   + +  K
Sbjct: 689  LLDSRTNELNEWRLKYSKLEPVIDEKRQLE---EKNRLFENRIQGLHQDIERLTKQLRQK 745

Query: 710  LQNYIQEN--MDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENI 767
              +  Q N  ++ T+ L +   + I+ L  ++N+ ++S        D + +++ L  E I
Sbjct: 746  QLDIDQLNWILNQTEGLLRNRDDSINSLETRLNNLQRS-------YDNE-RQKTLNFEQI 797

Query: 768  ESELSKYKSRICRLEESIAVMED--RRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVN 825
            +S+L +   +I +LE  I  +++   R   E    Q  +    +Q A SE TI   +L  
Sbjct: 798  QSQLQQAVDKINQLETQIKGLQNDLNRAKKEVTYQQNENDQMRQQIAKSEITIL--DLKQ 855

Query: 826  RLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQN---LQISLSDMQQHYNALVEK 882
              A   + +  + +   E+E   ++   K Q   E  QN   L     ++QQ Y  L+++
Sbjct: 856  NEARFKEVENRLNQSQKEVEKLTRQFNDKLQAYEELKQNNGLLDTKYKNLQQQYQELLQR 915

Query: 883  ANRTDLAESESTKYQTQLRDLESNLKRITHEHQTL---IVQKKKEIEDLEIEFNTQIESA 939
             N+ +   ++    + +  +LE+N K+   +   L   + QK +E+ +L+     Q+E  
Sbjct: 916  LNQLEQINNQYQILKAKNLELENNNKQYKIDQDRLNSTLNQKLQELNELQ-NLLPQLEDK 974

Query: 940  IRDKKVLNEKYE-KNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHV 993
            I       EKY     +Y  +L  +  E +  I      ++EL K+   + D+ V
Sbjct: 975  IHQLTPFEEKYAIVQPKYEQELN-KSDELQRKIRGQEQQLQELEKVKKIVQDQTV 1028



 Score = 69.3 bits (162), Expect = 8e-10
 Identities = 141/667 (21%), Positives = 276/667 (41%), Gaps = 81/667 (12%)

Query: 931  EFNTQIESAIRDKKVLNEKYEKNI-EYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELI 989
            E N Q  + I++ + +NE+ E  I E  T+LE+Q  E  N    L   +E+ + + ++ +
Sbjct: 95   ENNAQF-NRIKELEGVNEQQEIRIRELQTKLESQTTEISNY--KLKSEIEK-HIIRIKQL 150

Query: 990  DKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESK 1049
            +  + + +++     +     + +    L+  D+E+     K N  + ++ + +      
Sbjct: 151  ESELNEYKSKLGSVDQSLAGRLKEAERKLQDSDKELTNWKNKYNTDKTNWDNEIRRLNDL 210

Query: 1050 LAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKE-----TKLTFEM 1104
            L Q   +L++ +    +  +QL   +Q   + +  +RE + QI   K       KL  E 
Sbjct: 211  LTQKQKELDDYKNNQGKNYEQL---QQQLRQYETKIREYESQISTYKSDIDRLNKLLLER 267

Query: 1105 NIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKL 1164
            N   +E   + + ++    + ++              +K Q E +     + LQ +   L
Sbjct: 268  N---SEIDRLKNELKTRLQELDDWRSKFTNLQNQFNTMKSQYESKINDLTNTLQNRDRDL 324

Query: 1165 NTELQECYTKII-QLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSS 1223
            N + +  Y K+  Q   L +  +G    ++ +I  L+++L QL ++ D       +LR  
Sbjct: 325  N-DWKNKYAKLEGQFNNLGSLQSG----SESKITDLQNRLSQLQSDFDR---QATQLRD- 375

Query: 1224 ISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEET 1283
                   R  +I  L K+ L + E D       L  QL   +S+Y  LL   +    E  
Sbjct: 376  -------RDAQIQAL-KEKLQRLEQD----NFNLNNQLQDLQSRYNNLLKENEKLQNELR 423

Query: 1284 NKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXX 1343
            N+     ++  ++ +LQ   + L+    +Y D INQ+     E +D+ +A          
Sbjct: 424  NR---KNELDFMKQQLQQANDQLK----RYEDQINQLNEQIMECKDQIMALQNSKEM--- 473

Query: 1344 XXXXXXXDLRTENQSYKQMQEQSILNINEENAQLK-KSSXXXXXXXXXXXXRVNDA--EA 1400
                    L  + Q        ++  +   N QL+ K              +V+    E+
Sbjct: 474  --------LERQLQDLYSKSNDNVGELKSANDQLEGKDKDIADLRDQLNQFQVDRQIMES 525

Query: 1401 KVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELA 1460
             +  L +QL  K+ EI +   +  + L           QQL+E + R   L Y   S+L 
Sbjct: 526  MISSLNNQLANKNDEIQRLLAQNKLRL-----------QQLLELQSRYAQLDYLL-SDLK 573

Query: 1461 ILRLKMHEN-ANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAE-LNKALEEEVAK 1518
             + L+  +  A   E  Q   +++R    +EL +  ++S     Q  E + K L +E+ +
Sbjct: 574  GVELQNKQLIARISELQQLVDDLKRKLAQQELQLLQSKSNEFKIQELENIIKELAKEIQR 633

Query: 1519 TNEM--QTALENQEI--EIVTLNDEITNLQNM---VRASSSKIQKHVSFASDTKQGRDEQ 1571
             NE   Q   EN ++  +I+++ +EI  L+N+   +R    K+Q H+   +  KQ  D +
Sbjct: 634  LNEFLNQKLSENDKLNMQIISMENEINKLKNLEPLLRELEKKLQTHLDDIARLKQLLDSR 693

Query: 1572 LDNTMNK 1578
              N +N+
Sbjct: 694  -TNELNE 699



 Score = 41.1 bits (92), Expect = 0.25
 Identities = 113/551 (20%), Positives = 218/551 (39%), Gaps = 53/551 (9%)

Query: 144  VTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQI------IEAKNKATTXXX 197
            ++ L+N +  K++ +  L  + K+    +L+LQ +  + D +      +E +NK      
Sbjct: 527  ISSLNNQLANKNDEIQRLLAQNKLRLQQLLELQSRYAQLDYLLSDLKGVELQNKQLIARI 586

Query: 198  XXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEA------EWKDEKQRL-------LKDIE 244
                             + Q+ + + N   ++       E   E QRL       L + +
Sbjct: 587  SELQQLVDDLKRKLAQQELQLLQSKSNEFKIQELENIIKELAKEIQRLNEFLNQKLSEND 646

Query: 245  SKDVRISSLE-EANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAK-----Q 298
              +++I S+E E NKL         LE  KL   L+               L +      
Sbjct: 647  KLNMQIISMENEINKLKNLEPLLRELE-KKLQTHLDDIARLKQLLDSRTNELNEWRLKYS 705

Query: 299  SIEPSCEEKTEIEEKGSLEIANMTELTKKIE----LLEHLNCQIRQTNKELENKLATMGT 354
             +EP  +EK ++EEK  L    +  L + IE     L      I Q N  L      +  
Sbjct: 706  KLEPVIDEKRQLEEKNRLFENRIQGLHQDIERLTKQLRQKQLDIDQLNWILNQTEGLLRN 765

Query: 355  ESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVI 414
               +++S   + + L  ++S  N   K  + + Q+ S+ L Q  D KIN+ E  +++ + 
Sbjct: 766  RDDSINSLETRLNNL--QRSYDNERQKTLN-FEQIQSQ-LQQAVD-KINQLE-TQIKGLQ 819

Query: 415  QSLNKDLVDKEYVISEKDTXXXXXXXXXXG-KDTLIAQLQLEHQQHMEGPSLIHVGTNTE 473
              LN+   +  Y  +E D              D    + + +  ++    S   V   T 
Sbjct: 820  NDLNRAKKEVTYQQNENDQMRQQIAKSEITILDLKQNEARFKEVENRLNQSQKEVEKLTR 879

Query: 474  DVNEIAKVQEQLKQELNDEIKDVNVKDL---IEKLKSAEEQITQLNDEIDAANKNMIKVK 530
              N+  +  E+LKQ  N+ + D   K+L    ++L     Q+ Q+N++        ++++
Sbjct: 880  QFNDKLQAYEELKQ--NNGLLDTKYKNLQQQYQELLQRLNQLEQINNQYQILKAKNLELE 937

Query: 531  SNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDS 590
            +N+K + K  Q  ++  S ++   +E+  L   L  L  K+ +L   +    +    Y+ 
Sbjct: 938  NNNK-QYKIDQDRLN--STLNQKLQELNELQNLLPQLEDKIHQLTPFEEKYAIVQPKYEQ 994

Query: 591  GRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLV---QELHILQQ----KYDEVEDK 643
                  ++ +K+   E   +   K   +++ Q   L     E   L+Q    K  E++D 
Sbjct: 995  ELNKSDELQRKIRGQEQQLQELEKVKKIVQDQTVMLTVLFGECEGLRQQCTDKDGEIQDL 1054

Query: 644  LADISQLQSDQ 654
              +++QL SDQ
Sbjct: 1055 RFNVAQL-SDQ 1064


>UniRef50_A5DLM2 Cluster: Putative uncharacterized protein; n=1;
            Pichia guilliermondii|Rep: Putative uncharacterized
            protein - Pichia guilliermondii (Yeast) (Candida
            guilliermondii)
          Length = 1840

 Score =  133 bits (321), Expect = 4e-29
 Identities = 233/1171 (19%), Positives = 502/1171 (42%), Gaps = 122/1171 (10%)

Query: 472  TEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKS 531
            T D  E+ KV    K E ++ +KD    +L  KLK    Q       +      + K+K 
Sbjct: 716  TRDFQELQKVVASTK-EASETVKD----ELNLKLKELTSQYENTEKSLSTTTWELNKLKE 770

Query: 532  NHKL---KLKQMQKTIDNFSKVSDS-NKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVD 587
             HK+   KLK +Q+ +       DS      +  +ELH  ++      E   +L   L  
Sbjct: 771  AHKITEEKLKSLQEELSKTKAERDSLLASTKKFEKELHDTAKASESSNELVKSLTSKLAV 830

Query: 588  YDSGRMIESDVYKKM-IEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLAD 646
             + GR    D   KM  E+ NL +   +A    ++ + +L      L +K DE+E  L  
Sbjct: 831  AEEGRKKAEDGINKMNRELLNLTKLTKEAEKKAKTLENELNSLKKELSKKSDELEKGLKK 890

Query: 647  ISQLQS--DQVCSEIKSVHLE-EQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDK 703
            ++Q +S  +Q   +++   +E E+   +   +K+  LV  + +   E L   ++   N  
Sbjct: 891  LAQEKSSVEQQLEQLRKQMIELEKSHQVQLKEKDEKLV--DTEASNEHLMDKLRSAGNAI 948

Query: 704  EDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQ------FGIDAKI 757
            + +  +++   Q+  +L +++    A   + L+ +  ++ +    T+        I++  
Sbjct: 949  QKMKAEMEKIEQKRKELDEQVAASKASVDAFLVTEEKYKTEISTLTKKTDEQTSEIESLK 1008

Query: 758  QER---DLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLG---SYLQEKQK 811
            +E+   D  I N+E+ L+K K+    L E     E+ +  L+++ ++L    S L+E  +
Sbjct: 1009 EEKKALDEKILNVENNLTKVKAENEILTEK---SEEEKNKLKKQVEELEAKISSLKEDHE 1065

Query: 812  AYSEYTIQEDELVNR-LAVLMDHDRVVEKQL----LEIEHENKELQKKNQILLEENQNLQ 866
            + S   +QE EL+ + L V  +  + ++K++     ++  ++KEL++  ++   +   LQ
Sbjct: 1066 SKSLSGVQEKELLTKELQVAKEQLKKLQKEVSTKESQVLEKSKELEEATKLSDSKATALQ 1125

Query: 867  ISLSDMQ----QHYNALVEKANRTDLAESESTKYQTQLRDLESNL---KRITHEHQTLIV 919
              + +M+    +H + L  K        S+ T+ Q ++ +LES L   K    E +   +
Sbjct: 1126 SEVDEMRKKLDEHESTLKTKEVELKEKTSQITEVQAKVEELESELLIAKTKLEEAEATSL 1185

Query: 920  QKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVE 979
            +  +E+++ +   N+  +   + +  + E   KN ++  ++E QL+E K  +E       
Sbjct: 1186 KTTEELKETKSAENSARKQVAQLENEVKELKSKNADFAAEIE-QLKEQKTALELHKTTSS 1244

Query: 980  ELNKMNLELIDKHVQKQQTQ---SPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQ 1036
            E +  ++  +++ + K + Q   + D  ++   E++K  A+ ++  E I    + I + +
Sbjct: 1245 EKHASSVAELEEAISKAKLQIKKNLDTLKKKDEEVSKSKAIAEKHVETISRHEKSIEDQK 1304

Query: 1037 VSYMSM---VSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIK 1093
            +    +   VS+      +   +LE    ++Q ++ +L  SK    + +  +   + + K
Sbjct: 1305 LKINELETRVSETNELKEKVRKELEQSASKLQELTDELSLSK---NDFRTKLEAAERRAK 1361

Query: 1094 ELKETKLTFEMNIPKTEGMIISST---IEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEF 1150
            EL+ +    E  I +   ++ +++   ++  S+    ++               + E+E 
Sbjct: 1362 ELEVSLSDKEKEIEQDRALLSANSETAVKEYSEKVTKLEASISELKKQNHEKVKEVEDEA 1421

Query: 1151 IQERSVLQEQSAKL---NTELQECYTKIIQLETLNTELTGH-DVVNQ------EQINQLK 1200
             ++  +++E   KL     +L+E   + I+++ L  +L    D +N+      EQ+ +LK
Sbjct: 1422 ERQGQLVKELQKKLEGAEAKLKESSNENIKIDNLKNDLQKKLDTLNESFEEKDEQLKELK 1481

Query: 1201 -------SKLEQLNTENDNLLSTVAELRSSISSAVDQRG-----FEIAELWKQHLAQREA 1248
                    +L ++  E++ L  +  E ++ + SA D+ G      E A    + L +   
Sbjct: 1482 KEANQKTKQLSEIRAEHEGLKESAIESKNKLKSAEDEHGKTRTDLEAARKEVELLQEENE 1541

Query: 1249 DFQKTEHELRVQLSAFESKY----EQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEE 1304
            +F +   EL  + +  +++     E+L    +S+   E  K      V+SLQ ++ + E 
Sbjct: 1542 EFDEKVEELENEKTKLDAQISTLKEELAKVKESNNSAEGEKHALESTVSSLQERISNLET 1601

Query: 1305 HLRNLQEKYADV-INQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQ 1363
             L   + K A+V  N  +IL  E E  K+                  +L  +     + +
Sbjct: 1602 SLSTYEAKIAEVDENDEKILELEKEVHKL---------KEEFEKQREELEKQRDENSKQK 1652

Query: 1364 EQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEY 1423
            ++     NE   Q++K S               D  AK  E  H++  +D    +K  + 
Sbjct: 1653 DEIAKQKNEALKQIEKLSQENDALRA-------DLGAKTEE--HKVYYED---VKKAQKE 1700

Query: 1424 TITLTQRNDEFENVRQQLVEYEKRIEDLTYEKE--SELAILRLKMH--ENANHYETMQKE 1479
            ++TL Q+      V Q   E  +   DL   +E  SE+A L  KM   E  NH   +Q++
Sbjct: 1701 SLTLEQK------VTQMTEEIRRLNLDLASSQETASEVARLETKMKSLEEENHKLELQRQ 1754

Query: 1480 SEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDE 1539
            S    ++ + + N  + E V       EL    ++ V K+      +++  + +  ++++
Sbjct: 1755 SGEREMEKLNQYNDSLREDV----VARELRPDAKQYVRKSE-----VDDLMLLMADMDEK 1805

Query: 1540 ITNLQNMVRASSSKIQKHVSFASDTKQGRDE 1570
            I   + +++     +    S + + ++  D+
Sbjct: 1806 IQGYKKLLKKHGEDVSSDESLSEEEEEEEDD 1836



 Score =  124 bits (298), Expect = 3e-26
 Identities = 179/943 (18%), Positives = 417/943 (44%), Gaps = 80/943 (8%)

Query: 49   ERQIKFERAQKC-LENAALVSKRIKEHRKATAELLGRPFVPGISESLANTLKQKEILMEK 107
            E+Q++  R Q   LE +  V  + K+ +    E      +  +  S  N +++ +  MEK
Sbjct: 899  EQQLEQLRKQMIELEKSHQVQLKEKDEKLVDTEASNEHLMDKL-RSAGNAIQKMKAEMEK 957

Query: 108  IKQY-KELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNALSVLQVKMK 166
            I+Q  KEL ++     V                   +++ L+    E+ + +  L+ + K
Sbjct: 958  IEQKRKELDEQ-----VAASKASVDAFLVTEEKYKTEISTLTKKTDEQTSEIESLKEEKK 1012

Query: 167  IMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFI 226
             ++  IL+++  + +    ++A+N+  T                 E+ K ++ K  E   
Sbjct: 1013 ALDEKILNVENNLTK----VKAENEILTEKS--------------EEEKNKLKKQVEELE 1054

Query: 227  AMEAEWK-DEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXX 285
            A  +  K D + + L  ++ K++    L+ A + L+  + E+S + S++ ++ ++     
Sbjct: 1055 AKISSLKEDHESKSLSGVQEKELLTKELQVAKEQLKKLQKEVSTKESQVLEKSKELEEAT 1114

Query: 286  XXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLN--CQIRQTNK 343
                     L  QS      E  E+ +K  L+    T  TK++EL E  +   +++   +
Sbjct: 1115 KLSDSKATAL--QS------EVDEMRKK--LDEHESTLKTKEVELKEKTSQITEVQAKVE 1164

Query: 344  ELENKLATMGTESKAVSSPSKKGSP-LISRKSGRNTASKMKSPWSQLSSETLNQDTDKKI 402
            ELE++L    T+ +   + S K +  L   KS  N+A K  +       E  +++ D   
Sbjct: 1165 ELESELLIAKTKLEEAEATSLKTTEELKETKSAENSARKQVAQLENEVKELKSKNADFAA 1224

Query: 403  NKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEG 462
               ++ + +  ++ L+K    +++  S  +            K  L   L+ + ++  + 
Sbjct: 1225 EIEQLKEQKTALE-LHKTTSSEKHASSVAELEEAISKAKLQIKKNLDT-LKKKDEEVSKS 1282

Query: 463  PSLIHVGTNTEDVNEIAKVQEQLK-QELNDEIKDVN-VKDLIEK-LKSAEEQITQLNDEI 519
             ++      T   +E +   ++LK  EL   + + N +K+ + K L+ +  ++ +L DE+
Sbjct: 1283 KAIAEKHVETISRHEKSIEDQKLKINELETRVSETNELKEKVRKELEQSASKLQELTDEL 1342

Query: 520  DAANKNMIKVKSNH-KLKLKQMQKTIDNFSKVSDSNKEIVRLTEE--LHHLSQKVAELEE 576
             + +KN  + K    + + K+++ ++ +  K  + ++ ++    E  +   S+KV +LE 
Sbjct: 1343 -SLSKNDFRTKLEAAERRAKELEVSLSDKEKEIEQDRALLSANSETAVKEYSEKVTKLEA 1401

Query: 577  EKGNL--QLH--LVDYDSGRMIESDVYKKMIEMENLAETRLKAIS----LLESQKFDLVQ 628
                L  Q H  + + +     +  + K++ +    AE +LK  S     +++ K DL +
Sbjct: 1402 SISELKKQNHEKVKEVEDEAERQGQLVKELQKKLEGAEAKLKESSNENIKIDNLKNDLQK 1461

Query: 629  ELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLD 688
            +L  L + ++E +++L ++ + +++Q   ++  +  E +        KE A+  +N    
Sbjct: 1462 KLDTLNESFEEKDEQLKELKK-EANQKTKQLSEIRAEHE------GLKESAIESKNKLKS 1514

Query: 689  KEQLYG-TIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEK---------ISELLAK 738
             E  +G T  DLE  ++++   LQ   +EN +  +K+E++  EK         + E LAK
Sbjct: 1515 AEDEHGKTRTDLEAARKEV-ELLQ---EENEEFDEKVEELENEKTKLDAQISTLKEELAK 1570

Query: 739  INHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERK 798
            +     S    +  +++ +      I N+E+ LS Y+++I  ++E+   + +    + + 
Sbjct: 1571 VKESNNSAEGEKHALESTVSSLQERISNLETSLSTYEAKIAEVDENDEKILELEKEVHKL 1630

Query: 799  ADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQIL 858
             ++     +E +K   E + Q+DE+  +    +     + ++   +  +     +++++ 
Sbjct: 1631 KEEFEKQREELEKQRDENSKQKDEIAKQKNEALKQIEKLSQENDALRADLGAKTEEHKVY 1690

Query: 859  LEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLI 918
             E+ +  Q     ++Q    + E+  R +L  + S +  +++  LE+ +K +  E+  L 
Sbjct: 1691 YEDVKKAQKESLTLEQKVTQMTEEIRRLNLDLASSQETASEVARLETKMKSLEEENHKLE 1750

Query: 919  VQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLE 961
            +Q++    + E+E   Q   ++R+  V  E      +YV + E
Sbjct: 1751 LQRQS--GEREMEKLNQYNDSLREDVVARELRPDAKQYVRKSE 1791



 Score =  116 bits (278), Expect = 7e-24
 Identities = 200/1089 (18%), Positives = 439/1089 (40%), Gaps = 69/1089 (6%)

Query: 158  LSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQ 217
            L+ L+   KI E  +  LQE++++     ++   +T                  E  K  
Sbjct: 765  LNKLKEAHKITEEKLKSLQEELSKTKAERDSLLASTKKFEKELHDTAKASESSNELVKSL 824

Query: 218  MTKMQENFIAMEAEWKDEK--QRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLA 275
             +K+    +A E   K E    ++ +++ +        E+  K LE     +  E SK +
Sbjct: 825  TSKLA---VAEEGRKKAEDGINKMNRELLNLTKLTKEAEKKAKTLENELNSLKKELSKKS 881

Query: 276  QELEQXXXXXXXXXXXXXX----LAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELL 331
             ELE+                  L KQ IE     + +++EK    +         ++ L
Sbjct: 882  DELEKGLKKLAQEKSSVEQQLEQLRKQMIELEKSHQVQLKEKDEKLVDTEASNEHLMDKL 941

Query: 332  EHLNCQIRQTNKELEN-KLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLS 390
                  I++   E+E  +      + +  +S +   + L++ +  +   S +     + +
Sbjct: 942  RSAGNAIQKMKAEMEKIEQKRKELDEQVAASKASVDAFLVTEEKYKTEISTLTKKTDEQT 1001

Query: 391  SETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIA 450
            SE  +   +KK    +I  +E    +L K   + E +  + +             +  I+
Sbjct: 1002 SEIESLKEEKKALDEKILNVE---NNLTKVKAENEILTEKSEEEKNKLKKQVEELEAKIS 1058

Query: 451  QLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEI--KDVNV----KDLIEK 504
             L+ +H    E  SL  V        E+   +EQLK +L  E+  K+  V    K+L E 
Sbjct: 1059 SLKEDH----ESKSLSGVQEKELLTKELQVAKEQLK-KLQKEVSTKESQVLEKSKELEEA 1113

Query: 505  LKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEEL 564
             K ++ + T L  E+D   K + + +S  K K  +++   +  S++++   ++  L  EL
Sbjct: 1114 TKLSDSKATALQSEVDEMRKKLDEHESTLKTKEVELK---EKTSQITEVQAKVEELESEL 1170

Query: 565  HHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKF 624
                 K+ E E         L +  S    E+   K++ ++EN  +  LK+ +   + + 
Sbjct: 1171 LIAKTKLEEAEATSLKTTEELKETKSA---ENSARKQVAQLENEVK-ELKSKNADFAAEI 1226

Query: 625  DLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIEN 684
            + ++E     + +     +    S  + ++  S+ K + +++ +D L    +E++     
Sbjct: 1227 EQLKEQKTALELHKTTSSEKHASSVAELEEAISKAK-LQIKKNLDTLKKKDEEVSKSKAI 1285

Query: 685  LKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEK---MSAEKISELLAKINH 741
             +   E +    K +E+ K  I N+L+  + E  +L +K+ K    SA K+ EL  +++ 
Sbjct: 1286 AEKHVETISRHEKSIEDQKLKI-NELETRVSETNELKEKVRKELEQSASKLQELTDELSL 1344

Query: 742  EEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRI-CRLEESIAVMEDRRYSLERKAD 800
             +          + + +E ++ + + E E+ + ++ +    E ++    ++   LE    
Sbjct: 1345 SKNDFRTKLEAAERRAKELEVSLSDKEKEIEQDRALLSANSETAVKEYSEKVTKLEASIS 1404

Query: 801  QLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLE 860
            +L     EK K   +   ++ +LV  L   ++     E +L E  +EN ++      L +
Sbjct: 1405 ELKKQNHEKVKEVEDEAERQGQLVKELQKKLEG---AEAKLKESSNENIKIDNLKNDLQK 1461

Query: 861  ENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQ 920
            +   L  S  +  +    L ++AN       + TK  +++R     LK    E +     
Sbjct: 1462 KLDTLNESFEEKDEQLKELKKEAN-------QKTKQLSEIRAEHEGLKESAIESK----N 1510

Query: 921  KKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEE 980
            K K  ED   +  T +E+A ++ ++L E+ E+  E V +LE +  +    I  L   + +
Sbjct: 1511 KLKSAEDEHGKTRTDLEAARKEVELLQEENEEFDEKVEELENEKTKLDAQISTLKEELAK 1570

Query: 981  LNKMNLELI-DKHVQKQQTQS----PDYTEQYINEINKLNALLKQKDEEIIALNQKINNA 1035
            + + N     +KH  +    S        E  ++      A + + DE+I+ L ++++  
Sbjct: 1571 VKESNNSAEGEKHALESTVSSLQERISNLETSLSTYEAKIAEVDENDEKILELEKEVHKL 1630

Query: 1036 QVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKEL 1095
            +  +     + E +  + + + + + ++     KQ+    Q N+ L+  +  + ++ K  
Sbjct: 1631 KEEFEKQREELEKQRDENSKQKDEIAKQKNEALKQIEKLSQENDALRADLGAKTEEHKVY 1690

Query: 1096 KETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERS 1155
             E     ++   + E + +   +  M+++   ++                E      +  
Sbjct: 1691 YE-----DVKKAQKESLTLEQKVTQMTEEIRRLNLDLASSQET-----ASEVARLETKMK 1740

Query: 1156 VLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLS 1215
             L+E++ KL  + Q    ++ +L   N  L   DVV +E     K  + +  +E D+L+ 
Sbjct: 1741 SLEEENHKLELQRQSGEREMEKLNQYNDSLR-EDVVARELRPDAKQYVRK--SEVDDLML 1797

Query: 1216 TVAELRSSI 1224
             +A++   I
Sbjct: 1798 LMADMDEKI 1806



 Score = 71.7 bits (168), Expect = 2e-10
 Identities = 117/579 (20%), Positives = 234/579 (40%), Gaps = 72/579 (12%)

Query: 1049 KLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPK 1108
            KL + T++ EN E+ +   + +L   K+ ++  +  ++   +++ + K  + +   +  K
Sbjct: 743  KLKELTSQYENTEKSLSTTTWELNKLKEAHKITEEKLKSLQEELSKTKAERDSLLASTKK 802

Query: 1109 TEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTEL 1168
             E        + + D A   +            L V EE      R   ++   K+N EL
Sbjct: 803  FE--------KELHDTAKASESSNELVKSLTSKLAVAEEG-----RKKAEDGINKMNREL 849

Query: 1169 QECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAV 1228
                   + L  L  E        + ++N LK +L + + E +  L  +A+ +SS+   +
Sbjct: 850  -------LNLTKLTKEAEKKAKTLENELNSLKKELSKKSDELEKGLKKLAQEKSSVEQQL 902

Query: 1229 DQRGFEIAELWKQHLAQ-READFQ------KTEH-------------ELRVQLSAFESKY 1268
            +Q   ++ EL K H  Q +E D +        EH             +++ ++   E K 
Sbjct: 903  EQLRKQMIELEKSHQVQLKEKDEKLVDTEASNEHLMDKLRSAGNAIQKMKAEMEKIEQKR 962

Query: 1269 EQLLDSVQSSTQEETNKIVTME----QVTSLQNKLQDKEEHLRNL-QEKYA--DVINQIE 1321
            ++L + V +S       +VT E    ++++L  K  ++   + +L +EK A  + I  +E
Sbjct: 963  KELDEQVAASKASVDAFLVTEEKYKTEISTLTKKTDEQTSEIESLKEEKKALDEKILNVE 1022

Query: 1322 ILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSS 1381
               ++++ E                    +L  +  S K+  E   L+  +E   L K  
Sbjct: 1023 NNLTKVKAENEILTEKSEEEKNKLKKQVEELEAKISSLKEDHESKSLSGVQEKELLTKEL 1082

Query: 1382 XXXXXXXXXXXXRVNDAEAKVLELTHQLE----LKDS----------EIYQKTHEYTITL 1427
                         V+  E++VLE + +LE    L DS          E+ +K  E+  TL
Sbjct: 1083 QVAKEQLKKLQKEVSTKESQVLEKSKELEEATKLSDSKATALQSEVDEMRKKLDEHESTL 1142

Query: 1428 TQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHE-NANHYETMQ-----KESE 1481
              +  E +    Q+ E + ++E+L    ESEL I + K+ E  A   +T +     K +E
Sbjct: 1143 KTKEVELKEKTSQITEVQAKVEEL----ESELLIAKTKLEEAEATSLKTTEELKETKSAE 1198

Query: 1482 IERVKLIEELNVKITESVSLNKQ-VAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEI 1540
                K + +L  ++ E  S N    AE+ +  E++ A      T+ E     +  L + I
Sbjct: 1199 NSARKQVAQLENEVKELKSKNADFAAEIEQLKEQKTALELHKTTSSEKHASSVAELEEAI 1258

Query: 1541 TNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKE 1579
            +  +  ++ +   ++K     S +K   ++ ++     E
Sbjct: 1259 SKAKLQIKKNLDTLKKKDEEVSKSKAIAEKHVETISRHE 1297


>UniRef50_A0DAF7 Cluster: Chromosome undetermined scaffold_43, whole
            genome shotgun sequence; n=2; Paramecium tetraurelia|Rep:
            Chromosome undetermined scaffold_43, whole genome shotgun
            sequence - Paramecium tetraurelia
          Length = 2374

 Score =  132 bits (320), Expect = 6e-29
 Identities = 273/1304 (20%), Positives = 560/1304 (42%), Gaps = 101/1304 (7%)

Query: 325  TKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKS 384
            T+ I+ L+  N ++ QT  E +N+L     E KA +    +   L ++K  ++  S+ + 
Sbjct: 249  TEAIQELKKQN-ELLQTQLEDQNQLQQENDELKA-NKLQLQDQLLQAQKQLQDLLSE-QI 305

Query: 385  PWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXG 444
            P    SS ++   TD +    +I++L+   Q+LN+ + + +    E D            
Sbjct: 306  PKQVTSSGSIQFQTDPQ-KALQISQLQQTNQALNQQIEELQQQRKE-DLQKFQDMIGNGV 363

Query: 445  KDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKD-VNVKDLIE 503
             +  I  L  E QQ      ++        +++I + Q  L+ +L  + K  +++ D ++
Sbjct: 364  NEQQIVALMSEKQQLQSDLRMLQ-----SKLDQIQQEQLALQSQLTQKTKQLIDIHDDVK 418

Query: 504  KLKSAEEQITQLNDEIDAANKNMIKVKSNHK--LKLKQMQKTIDNFS-KVSDSNKEIVRL 560
            + +  ++Q  QL++E +   K + KVKS ++  L+L+    T +    K+    K+I  L
Sbjct: 419  QEEQIQQQ-QQLSNENELLKKQLEKVKSQYQELLELQSQNLTPNGLQEKLLQQTKQIHDL 477

Query: 561  TEELHHLSQKV-AELEEEKGNL---QLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAI 616
             E+ H L  ++  E+ +  G L   +  L D  +   + +D Y  +++ +   + + +  
Sbjct: 478  EEQNHILQHQIETEIPQLVGELTETKQKLKDAITDAQLWNDKYHDLLDHKQSVQPQHQEE 537

Query: 617  SLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKK 676
             + +  K +  Q L  LQQ+Y   ++ L  + Q Q +   +E    +L +  D L  S +
Sbjct: 538  DIAKMTKEEAQQALSDLQQQY---QNSLLKLKQAQDN---AEENKQNLIKAQDNLDNSSR 591

Query: 677  ELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELL 736
            +  L    LK  KE L    ++L+N   D+  K Q   Q+ +DL ++LE+ +AE      
Sbjct: 592  DAKL----LKEQKEILEKQTENLQNVNNDLKQKDQENRQQILDLRNQLEQENAEFWRTEY 647

Query: 737  AKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLE 796
             K+ ++    I TQF    ++  +  +I+  E   ++    + +  E +    + +  L+
Sbjct: 648  QKLANKHGEDIPTQFPSSKQVVPQ--HIQKDEGNQTEAIQELKKQNELLQTQLEDQNQLQ 705

Query: 797  RKADQL-GSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKN 855
            ++ D+L  + LQ + +        +D L  ++   +     ++ Q    +    +L   N
Sbjct: 706  QENDELKANKLQLQDQLLQAQKQLQDLLSEQIPKQVTSSGSIQFQTDPQKALVDQLIIIN 765

Query: 856  QILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEH- 914
            Q+ ++      I++   ++ +  ++    +  L  SE  + Q+ LR L+S L +I  E  
Sbjct: 766  QLSIKLINRRIITIK--KRRFIEVLRYDWKWTLM-SEKQQLQSDLRMLQSKLDQIQQEQL 822

Query: 915  --QTLIVQKKKEIEDLEIEFNTQIESAIRDKKVL---NEKYEKNIEYVTQLEAQLQEYKN 969
              Q+ + QK K++  ++I  + + E  I+ ++ L   NE  +K +E V     +L E ++
Sbjct: 823  ALQSQLTQKTKQL--IDIHDDVKQEEQIQQQQQLSNENELLKKQLEKVKSQYQELLELQS 880

Query: 970  NIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTE--QYINEINKLNALLKQKDEEIIA 1027
                 N   E+L +   ++ D   Q    Q    TE  Q + E+ +    LK    +   
Sbjct: 881  QNLTPNGLQEKLLQQTKQIHDLEEQNHILQHQIETEIPQLVGELTETKQKLKDAITDAQL 940

Query: 1028 LNQKINNAQVSYMSMVSDY-ESKLAQFTTK-----LENMEEEMQRVSKQLLDSKQHNEE- 1080
             N K ++      S+   + E  +A+ T +     L +++++ Q    +L  ++ + EE 
Sbjct: 941  WNDKYHDLLDHKQSVQPQHQEEDIAKMTKEEAQQALSDLQQQYQNSLLKLKQAQDNAEEN 1000

Query: 1081 LQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXX 1140
             Q L++ QD+     ++ KL       K +  I+    E + +  N++            
Sbjct: 1001 KQNLIKAQDNLDNSSRDAKLL------KEQKEILEKQTENLQNVNNDLKQKDQENRQQIL 1054

Query: 1141 XLKVQEEEEFIQ-ERSVLQEQSAKLNTELQECY---TKIIQLETLNTELTGHDVVNQ--E 1194
             LK Q E+E  +  R+  Q+ + K   ++   +    +++       E    + + +  +
Sbjct: 1055 DLKNQLEQENAEFWRTEYQKLANKHGEDIPTQFPSSKQVVPQHIQKDEGNQTEAIQELKK 1114

Query: 1195 QINQLKSKLE---QLNTENDNLLSTVAELRSSISSAVDQRGFEIAE-LWKQHLAQREADF 1250
            Q   L+++LE   QL  END L +   +L+  +  A  Q    ++E + KQ  +     F
Sbjct: 1115 QNELLQTQLEDQNQLQQENDELKANKLQLQDQLLQAQKQLQDLLSEQIPKQVTSSGSIQF 1174

Query: 1251 QKTEHELRVQLSAFESKYE---QLLDSVQSSTQEETNKI-------VTMEQVTSLQNKLQ 1300
            Q T+ +  +Q+S  +   +   Q ++ +Q   +E+  K        V  +Q+ +L ++ Q
Sbjct: 1175 Q-TDPQKALQISQLQQTNQALNQQIEELQQQRKEDLQKFQDMIGNGVNEQQIVALMSEKQ 1233

Query: 1301 DKEEHLRNLQEKYADVINQIEILRSEI-EDEKVAFXXXXXXXXXXXXXXXXDLRTENQSY 1359
              +  LR LQ K   V  +   L+S++ +  K                    L  EN+  
Sbjct: 1234 QLQSDLRMLQSKLDQVQQEQLALQSQLTQKTKQLIDIHDDVKQEEQIQQQQQLSNENELL 1293

Query: 1360 KQMQEQSILNINEENAQLKKSSXX---XXXXXXXXXXRVNDAEAKVLELTHQLELKDSEI 1416
            K+ Q + + +  +E  +L+  +               +++D E +   L HQ+E   +EI
Sbjct: 1294 KK-QLEKVKSQYQELLELQSQNLTPNGLQEKLLQQTKQIHDLEEQNHILQHQIE---TEI 1349

Query: 1417 YQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETM 1476
             Q   E T T  +  D   + +    +Y + + D       ++  L  K+ +  N    +
Sbjct: 1350 PQLVGELTQTKQKLKDAITDAQLWNDKYHQLLGDHQQASPQQILDLEQKLTDAQNE---V 1406

Query: 1477 QKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQE-IEIVT 1535
            QKE E +   L +E   +++ S +  K        L E V + NE++  LE QE   I  
Sbjct: 1407 QKEKE-KYNHLFQEQYSQLSPSSAQAK--------LLEAVNQINELKAQLEAQEKARIAN 1457

Query: 1536 LNDEITNL-QNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNK 1578
            L ++  +L  + ++      QK V       + + +Q++   N+
Sbjct: 1458 LIEKEPSLAMDKLQEDLLNYQKQVEMQEKLNEIQLQQIEFLRNQ 1501



 Score =  108 bits (259), Expect = 1e-21
 Identities = 219/1056 (20%), Positives = 449/1056 (42%), Gaps = 66/1056 (6%)

Query: 560  LTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIES--DVYKKMIEMENLAET-RLKAI 616
            L EE+   ++ + + EEE  +LQ H ++ D  +M+    +V  ++ + E+ A   + K  
Sbjct: 30   LKEEILQETKLIHQQEEEIQSLQ-HQIEQDLPQMVGKLEEVQLRLKQAEDEANLWKSKHQ 88

Query: 617  SLLESQ---KFDLVQELHILQQKYDEVEDKLAD--ISQLQSDQVCSEIKSVHLEEQ--ID 669
             LLE++   +   V +  I +   ++ +  + D  I Q Q++Q   E ++  +E+Q  + 
Sbjct: 89   MLLENRPNIQQPTVDKQSIKELNLEQAQQAVQDLLIKQEQNEQHKDEQQNKIMEQQNQLQ 148

Query: 670  ALSASKKELALVIENLKLDKEQLYGTIKDLENDK-EDIMNKLQNYIQENMDLTDKLEKMS 728
             L   K  L     NL L++ Q+     DL+  + E++ N+     Q+ +DL ++LE+ +
Sbjct: 149  QLQDEKDNLQRE-NNLLLEQNQIVKQQNDLQKKQVEELKNQDLENRQQILDLKNQLEQEN 207

Query: 729  AEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVM 788
            AE       K+ ++    I TQF    ++  +  +I+  E   ++    + +  E +   
Sbjct: 208  AEFWRTEYQKLANKHGEDIPTQFPSSKQVVPQ--HIQKDEGNQTEAIQELKKQNELLQTQ 265

Query: 789  EDRRYSLERKADQL-GSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQL-LEIEH 846
             + +  L+++ D+L  + LQ + +        +D L  ++   +     ++ Q   +   
Sbjct: 266  LEDQNQLQQENDELKANKLQLQDQLLQAQKQLQDLLSEQIPKQVTSSGSIQFQTDPQKAL 325

Query: 847  ENKELQKKNQILLEENQNLQIS-LSDMQQHYNALVEKANRTDLAE--SESTKYQTQLRDL 903
            +  +LQ+ NQ L ++ + LQ     D+Q+  + +    N   +    SE  + Q+ LR L
Sbjct: 326  QISQLQQTNQALNQQIEELQQQRKEDLQKFQDMIGNGVNEQQIVALMSEKQQLQSDLRML 385

Query: 904  ESNLKRITHEH---QTLIVQKKKEIEDLEIEFNTQIESAIRDKKVL---NEKYEKNIEYV 957
            +S L +I  E    Q+ + QK K++  ++I  + + E  I+ ++ L   NE  +K +E V
Sbjct: 386  QSKLDQIQQEQLALQSQLTQKTKQL--IDIHDDVKQEEQIQQQQQLSNENELLKKQLEKV 443

Query: 958  TQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTE--QYINEINKLN 1015
                 +L E ++     N   E+L +   ++ D   Q    Q    TE  Q + E+ +  
Sbjct: 444  KSQYQELLELQSQNLTPNGLQEKLLQQTKQIHDLEEQNHILQHQIETEIPQLVGELTETK 503

Query: 1016 ALLKQKDEEIIALNQKINNAQVSYMSMVSDY-ESKLAQFTTK-----LENMEEEMQRVSK 1069
              LK    +    N K ++      S+   + E  +A+ T +     L +++++ Q    
Sbjct: 504  QKLKDAITDAQLWNDKYHDLLDHKQSVQPQHQEEDIAKMTKEEAQQALSDLQQQYQNSLL 563

Query: 1070 QLLDSKQHNEE-LQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNV 1128
            +L  ++ + EE  Q L++ QD+     ++ KL       K +  I+    E + +  N++
Sbjct: 564  KLKQAQDNAEENKQNLIKAQDNLDNSSRDAKLL------KEQKEILEKQTENLQNVNNDL 617

Query: 1129 DXXXXXXXXXXXXLKVQEEEEFIQ-ERSVLQEQSAKLNTELQECYTKIIQLETLNTELTG 1187
                         L+ Q E+E  +  R+  Q+ + K   ++   +    Q+   + +   
Sbjct: 618  KQKDQENRQQILDLRNQLEQENAEFWRTEYQKLANKHGEDIPTQFPSSKQVVPQHIQ--- 674

Query: 1188 HDVVNQ-EQINQLKSKLEQLNT--ENDNLLSTV-AELRSSISSAVDQRGFEIAELWKQHL 1243
             D  NQ E I +LK + E L T  E+ N L     EL+++     DQ     A+   Q L
Sbjct: 675  KDEGNQTEAIQELKKQNELLQTQLEDQNQLQQENDELKANKLQLQDQ--LLQAQKQLQDL 732

Query: 1244 AQREADFQKTEH-ELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDK 1302
               +   Q T    ++ Q    ++  +QL+   Q S +    +I+T+++   ++    D 
Sbjct: 733  LSEQIPKQVTSSGSIQFQTDPQKALVDQLIIINQLSIKLINRRIITIKKRRFIEVLRYDW 792

Query: 1303 EEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQM 1362
            +  L + +++    +  ++    +I+ E++A                 D++ E Q  +Q 
Sbjct: 793  KWTLMSEKQQLQSDLRMLQSKLDQIQQEQLALQSQLTQKTKQLIDIHDDVKQEEQIQQQQ 852

Query: 1363 QEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHE 1422
            Q  +   + ++  +  KS               N  + K+L+ T Q+   + + +   H+
Sbjct: 853  QLSNENELLKKQLEKVKSQYQELLELQSQNLTPNGLQEKLLQQTKQIHDLEEQNHILQHQ 912

Query: 1423 YTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHY-ETMQKESE 1481
                + Q   E    +Q+L   +  I D     +    +L  K      H  E + K ++
Sbjct: 913  IETEIPQLVGELTETKQKL---KDAITDAQLWNDKYHDLLDHKQSVQPQHQEEDIAKMTK 969

Query: 1482 IERVKLIEELNVKITESVSLNKQV---AELNK--ALEEEVAKTNEMQTA-LENQEIEIVT 1535
             E  + + +L  +   S+   KQ    AE NK   ++ +    N  + A L  ++ EI  
Sbjct: 970  EEAQQALSDLQQQYQNSLLKLKQAQDNAEENKQNLIKAQDNLDNSSRDAKLLKEQKEI-- 1027

Query: 1536 LNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQ 1571
            L  +  NLQN+      K Q++     D K   +++
Sbjct: 1028 LEKQTENLQNVNNDLKQKDQENRQQILDLKNQLEQE 1063



 Score =  101 bits (243), Expect = 1e-19
 Identities = 219/1088 (20%), Positives = 463/1088 (42%), Gaps = 109/1088 (10%)

Query: 430  EKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQEL 489
            +KD            K   + Q QLE Q  ++  +        +  +++ + Q+QL+  L
Sbjct: 1099 QKDEGNQTEAIQELKKQNELLQTQLEDQNQLQQENDELKANKLQLQDQLLQAQKQLQDLL 1158

Query: 490  NDEI-KDVNVKDLIEKLKSAEE--QITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDN 546
            +++I K V     I+     ++  QI+QL     A N+ + +++   K  L++ Q  I N
Sbjct: 1159 SEQIPKQVTSSGSIQFQTDPQKALQISQLQQTNQALNQQIEELQQQRKEDLQKFQDMIGN 1218

Query: 547  FSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEME 606
                  + ++IV L  E   L   +  L+ +   +Q   +       ++S + +K  ++ 
Sbjct: 1219 ----GVNEQQIVALMSEKQQLQSDLRMLQSKLDQVQQEQL------ALQSQLTQKTKQLI 1268

Query: 607  NLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEE 666
            ++ +  +K    ++ Q+  L  E  +L+++ ++V+ +  ++ +LQS  +        L +
Sbjct: 1269 DIHDD-VKQEEQIQQQQ-QLSNENELLKKQLEKVKSQYQELLELQSQNLTPNGLQEKLLQ 1326

Query: 667  QIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEK 726
            Q   +   +++  ++   ++ +  QL G +   +   +D +   Q +  +   L    ++
Sbjct: 1327 QTKQIHDLEEQNHILQHQIETEIPQLVGELTQTKQKLKDAITDAQLWNDKYHQLLGDHQQ 1386

Query: 727  MSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIA 786
             S ++I +L  K+  + Q+++Q +     K +   L+ E   S+LS   ++  +L E++ 
Sbjct: 1387 ASPQQILDLEQKLT-DAQNEVQKE-----KEKYNHLFQEQY-SQLSPSSAQ-AKLLEAVN 1438

Query: 787  VMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEH 846
             + + +  LE +     + L EK+ + +   +QED L  +  V M  +++ E QL +IE 
Sbjct: 1439 QINELKAQLEAQEKARIANLIEKEPSLAMDKLQEDLLNYQKQVEMQ-EKLNEIQLQQIEF 1497

Query: 847  ENKEL---QKKNQILLE-ENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRD 902
               +L    +K QI  + E++  Q SL D      A + +  + +L  +++T  Q Q   
Sbjct: 1498 LRNQLAQRDQKQQIKQDQEDEETQQSLRDQNIILQAQLAQKQK-ELDNAQATLIQNQQII 1556

Query: 903  LESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQ-LE 961
             E   +++  E        KK+  DL     +Q   A + K++L +K  +  + + Q  +
Sbjct: 1557 DEQQQEQLKSEFW------KKQYTDLI----SQQAPADQQKQILKQKESELTQEIKQPSQ 1606

Query: 962  AQLQEYKNNIENLNMNVEELNKMNLEL---IDKHVQK-QQTQSPDYTEQYINEINKLNAL 1017
            +     +  I NL +    L +  ++    + K  Q  + T SP   +    +I KLN  
Sbjct: 1607 SNNDNLQEQINNLLIERASLQQQLIQAQGKLGKATQNLESTDSPQQGQDSQGQIQKLN-- 1664

Query: 1018 LKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQH 1077
              ++ +E+   NQ +     S +S   D   KLAQ   K  N +  +   SK ++D   +
Sbjct: 1665 --REVQELQQRNQNLIEQMKSALSG-DDQGQKLAQLIEK--NNQLSLNN-SKLMIDLDVN 1718

Query: 1078 NEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXX 1137
             +EL   +++Q      +++ K   + ++ +   + +S   + +      VD        
Sbjct: 1719 QKEL---LKQQGQNQVLIEKVKDLSDPSVTENAKLRVSDLQKQIDLIGQQVDFWKQKYQQ 1775

Query: 1138 XXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQIN 1197
                   Q     IQ + + Q Q        QE    ++Q  T  T+L      N+ QIN
Sbjct: 1776 VLNEYSQQLSPTSIQRKMLEQAQYI----HQQEEALLMLQQTTDQTKLD-----NENQIN 1826

Query: 1198 QLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHEL 1257
            QL+ + + LN EN NL   + E  +           +  ++ +QH+  ++  + K     
Sbjct: 1827 QLRIENKILNDENVNLKKRIQEQEN-----------QSQQISRQHVLSQD-QYDK----- 1869

Query: 1258 RVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKE-EHLRNLQEKYADV 1316
              Q+  ++ KY++ L ++    Q+  +  +  +Q  S QN   DK+ + +   Q++ +++
Sbjct: 1870 --QIQFWKEKYQEALQALHKDPQKVQD--IIQQQEESAQNIQSDKDWQPILKQQDQSSEI 1925

Query: 1317 INQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQ 1376
            I+++       + E V F                +L  + Q     Q+ +I +   + +Q
Sbjct: 1926 IDKLRSENQTFQGE-VTF----------YKKRVFELEQQQQKPDPSQQDTIQSQQYQISQ 1974

Query: 1377 LKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFEN 1436
            L +              + ND    V++ +   E+      Q T  Y     Q+ D+ E 
Sbjct: 1975 LDRDLQKALQTSAYWEQKYND----VVQQSINKEVGQRGDAQNTASY---WRQKFDQAEQ 2027

Query: 1437 VRQQLVE-YEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKI 1495
             RQQL++  +++ E +    +S  +IL+ ++ E      T  +  E ++++L  + N   
Sbjct: 2028 SRQQLMQVIQEKEEQIEQHMQSFQSILKDELKEEL----TKIRNQERQKIELQLQQNQPY 2083

Query: 1496 TESVSLNK 1503
             ES  + K
Sbjct: 2084 NESNLIQK 2091



 Score = 99.5 bits (237), Expect = 7e-19
 Identities = 222/1174 (18%), Positives = 483/1174 (41%), Gaps = 100/1174 (8%)

Query: 237  QRLLKDIESKDVRISSLEEANKLLEAA---RFEISLEHSKL-AQELEQXXXXXXXXXXXX 292
            Q + KD  ++   I  L++ N+LL+     + ++  E+ +L A +L+             
Sbjct: 1096 QHIQKDEGNQTEAIQELKKQNELLQTQLEDQNQLQQENDELKANKLQLQDQLLQAQKQLQ 1155

Query: 293  XXLAKQ---SIEPSCEEKTEIEEKGSLEIANMTELTKKI-ELLEHLNCQIRQTNKELENK 348
              L++Q    +  S   + + + + +L+I+ + +  + + + +E L  Q ++  ++ ++ 
Sbjct: 1156 DLLSEQIPKQVTSSGSIQFQTDPQKALQISQLQQTNQALNQQIEELQQQRKEDLQKFQDM 1215

Query: 349  LATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIA 408
            +     E + V+  S+K       +  ++   +++     L S+ L Q T + I+ ++  
Sbjct: 1216 IGNGVNEQQIVALMSEKQQLQSDLRMLQSKLDQVQQEQLALQSQ-LTQKTKQLIDIHDDV 1274

Query: 409  KLEMVIQ-----SLNKDLVDK--EYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQH-M 460
            K E  IQ     S   +L+ K  E V S+                     LQ   Q H +
Sbjct: 1275 KQEEQIQQQQQLSNENELLKKQLEKVKSQYQELLELQSQNLTPNGLQEKLLQQTKQIHDL 1334

Query: 461  EGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNV-KDLIEKLKSAEEQITQLNDEI 519
            E  + I       ++ ++     Q KQ+L D I D  +  D   +L    +Q +     +
Sbjct: 1335 EEQNHILQHQIETEIPQLVGELTQTKQKLKDAITDAQLWNDKYHQLLGDHQQASP-QQIL 1393

Query: 520  DAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKG 579
            D   K         K K K      + +S++S S+ +  +L E ++ +++  A+LE ++ 
Sbjct: 1394 DLEQKLTDAQNEVQKEKEKYNHLFQEQYSQLSPSSAQ-AKLLEAVNQINELKAQLEAQEK 1452

Query: 580  NLQLHLVDYDSGRM---IESDV--YKKMIEM-ENLAETRLKAISLLESQKFDLVQELHIL 633
                +L++ +       ++ D+  Y+K +EM E L E +L+ I  L +Q     Q+  I 
Sbjct: 1453 ARIANLIEKEPSLAMDKLQEDLLNYQKQVEMQEKLNEIQLQQIEFLRNQLAQRDQKQQIK 1512

Query: 634  QQKYDE-VEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQL 692
            Q + DE  +  L D + +   Q+  + K +   +   A     +++    +  +L  E  
Sbjct: 1513 QDQEDEETQQSLRDQNIILQAQLAQKQKEL---DNAQATLIQNQQIIDEQQQEQLKSEFW 1569

Query: 693  YGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHE--EQSKIQTQ 750
                 DL + +     + Q   Q+  +LT ++++ S      L  +IN+   E++ +Q Q
Sbjct: 1570 KKQYTDLISQQAPADQQKQILKQKESELTQEIKQPSQSNNDNLQEQINNLLIERASLQQQ 1629

Query: 751  F-GIDAKIQERDLYIENIESELSKYKSR--ICRLEESIAVMEDRRYSLERKADQLGSYLQ 807
                  K+ +    +E+ +S      S+  I +L   +  ++ R  +L  +     S   
Sbjct: 1630 LIQAQGKLGKATQNLESTDSPQQGQDSQGQIQKLNREVQELQQRNQNLIEQMKSALSGDD 1689

Query: 808  EKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEEN--QNL 865
            + QK            +N   +++D D V +K+LL+ + +N+ L +K + L + +  +N 
Sbjct: 1690 QGQKLAQLIEKNNQLSLNNSKLMIDLD-VNQKELLKQQGQNQVLIEKVKDLSDPSVTENA 1748

Query: 866  QISLSDMQQHYNALVEKANR-TDLAESESTKYQTQLRDLESNLKRIT-----HEHQTLIV 919
            ++ +SD+Q+  + + ++ +      +    +Y  QL       K +      H+ +  ++
Sbjct: 1749 KLRVSDLQKQIDLIGQQVDFWKQKYQQVLNEYSQQLSPTSIQRKMLEQAQYIHQQEEALL 1808

Query: 920  QKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKN----NIENLN 975
              ++  +  +++   QI     + K+LN++     + + + E Q Q+       + +  +
Sbjct: 1809 MLQQTTDQTKLDNENQINQLRIENKILNDENVNLKKRIQEQENQSQQISRQHVLSQDQYD 1868

Query: 976  MNVE---ELNKMNLELIDKHVQKQQT--QSPDYTEQYINEINKLNALLKQKDEEIIALNQ 1030
              ++   E  +  L+ + K  QK Q   Q  + + Q I        +LKQ+D+    ++ 
Sbjct: 1869 KQIQFWKEKYQEALQALHKDPQKVQDIIQQQEESAQNIQSDKDWQPILKQQDQSSEIID- 1927

Query: 1031 KINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDD 1090
            K+ +   ++   V+ Y+ ++ +    LE  +++     +  + S+Q+       + + D 
Sbjct: 1928 KLRSENQTFQGEVTFYKKRVFE----LEQQQQKPDPSQQDTIQSQQYQ------ISQLDR 1977

Query: 1091 QIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLK-----VQ 1145
             +++  +T   +E          I+  +    D  N                +     +Q
Sbjct: 1978 DLQKALQTSAYWEQKYNDVVQQSINKEVGQRGDAQNTASYWRQKFDQAEQSRQQLMQVIQ 2037

Query: 1146 EEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELT------------------G 1187
            E+EE I++   +Q   + L  EL+E  TKI   E    EL                    
Sbjct: 2038 EKEEQIEQH--MQSFQSILKDELKEELTKIRNQERQKIELQLQQNQPYNESNLIQKLKEQ 2095

Query: 1188 HDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLA-QR 1246
            H+V  Q+ I +   +++QL   N          +  I     QR  E+ EL +QHL   +
Sbjct: 2096 HEVEKQQLIQEFLRRIDQLLQSNVQKYPEGENWKELILRYEKQRQNELYEL-RQHLEILQ 2154

Query: 1247 EADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEET-------NKIVT--MEQVTSLQN 1297
             +  Q  + E   +  A+E+   +L + +Q    +E         K++    +QV  LQN
Sbjct: 2155 RSQIQTKDIEFYAERRAYENAINELKNRIQQDDPQELYDTIEYQRKVILDLEDQVGFLQN 2214

Query: 1298 KLQDKEEHLRNLQEKYADVINQIEILRSEIEDEK 1331
            +  + E H+  L ++   + + I   + + ++ K
Sbjct: 2215 ERNNLEMHIMQLNQQIDQLKDNISRYQMQSDNRK 2248



 Score = 96.3 bits (229), Expect = 6e-18
 Identities = 181/889 (20%), Positives = 378/889 (42%), Gaps = 117/889 (13%)

Query: 738  KINHEEQSKIQT-QFGID-------AKIQERDLYIENIESELSKYKSRICRLEESIAVME 789
            K+ H+++ +IQ+ Q  I+        K++E  L ++  E E + +KS+   L E+   ++
Sbjct: 39   KLIHQQEEEIQSLQHQIEQDLPQMVGKLEEVQLRLKQAEDEANLWKSKHQMLLENRPNIQ 98

Query: 790  DRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENK 849
                  ++   +L   L++ Q+A  +  I++++         +     + QL +++ E  
Sbjct: 99   QPTVD-KQSIKELN--LEQAQQAVQDLLIKQEQNEQHKDEQQNKIMEQQNQLQQLQDEKD 155

Query: 850  ELQKKNQILLEENQ--NLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNL 907
             LQ++N +LLE+NQ    Q  L   Q       +  NR  + + ++   Q       +  
Sbjct: 156  NLQRENNLLLEQNQIVKQQNDLQKKQVEELKNQDLENRQQILDLKNQLEQENAEFWRTEY 215

Query: 908  KRITHEH----QTLIVQKKKEI-EDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEA 962
            +++ ++H     T     K+ + + ++ +   Q E AI++ K  NE  +  +E   QL+ 
Sbjct: 216  QKLANKHGEDIPTQFPSSKQVVPQHIQKDEGNQTE-AIQELKKQNELLQTQLEDQNQLQQ 274

Query: 963  QLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKD 1022
            +  E K N   L   + +  K   +L+ + + KQ T S     Q+  +  K    + Q  
Sbjct: 275  ENDELKANKLQLQDQLLQAQKQLQDLLSEQIPKQVTSSGSI--QFQTDPQKA-LQISQLQ 331

Query: 1023 EEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQ 1082
            +   ALNQ+I   Q          +  L +F   + N   E Q V+  L+  KQ   +LQ
Sbjct: 332  QTNQALNQQIEELQ-------QQRKEDLQKFQDMIGNGVNEQQIVA--LMSEKQ---QLQ 379

Query: 1083 ILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXL 1142
              +R    ++ ++++ +L  +  + +    +I      + DD    +             
Sbjct: 380  SDLRMLQSKLDQIQQEQLALQSQLTQKTKQLID-----IHDDVKQEE------------- 421

Query: 1143 KVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTG--HDVVNQ-EQINQL 1199
            ++Q++++   E  +L++Q  K+ ++ QE    +++L++ N    G    ++ Q +QI+ L
Sbjct: 422  QIQQQQQLSNENELLKKQLEKVKSQYQE----LLELQSQNLTPNGLQEKLLQQTKQIHDL 477

Query: 1200 KSK----LEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELW----------KQHL-- 1243
            + +      Q+ TE   L+  + E +  +  A+       A+LW          KQ +  
Sbjct: 478  EEQNHILQHQIETEIPQLVGELTETKQKLKDAITD-----AQLWNDKYHDLLDHKQSVQP 532

Query: 1244 AQREADFQK-TEHELRVQLSAFESKYE-QLLDSVQSSTQEETNKIVTMEQVTSLQNKLQD 1301
              +E D  K T+ E +  LS  + +Y+  LL   Q+    E NK    + +   Q+ L +
Sbjct: 533  QHQEEDIAKMTKEEAQQALSDLQQQYQNSLLKLKQAQDNAEENK----QNLIKAQDNLDN 588

Query: 1302 KEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQ 1361
                 + L+E+   +  Q E L++   D K                    L  EN  + +
Sbjct: 589  SSRDAKLLKEQKEILEKQTENLQNVNNDLK----QKDQENRQQILDLRNQLEQENAEFWR 644

Query: 1362 MQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTH 1421
             + Q + N + E+   +  S              N  EA + EL  Q EL  +++  +  
Sbjct: 645  TEYQKLANKHGEDIPTQFPSSKQVVPQHIQKDEGNQTEA-IQELKKQNELLQTQLEDQNQ 703

Query: 1422 EYTITLTQRNDEFE----NVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQ 1477
                 L Q NDE +     ++ QL++ +K+++DL  E+     I +      +  ++T  
Sbjct: 704  -----LQQENDELKANKLQLQDQLLQAQKQLQDLLSEQ-----IPKQVTSSGSIQFQTDP 753

Query: 1478 KESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTAL-ENQEI--EIV 1534
            +++ ++++ +I +L++K+     +N+++  + K    EV + +   T + E Q++  ++ 
Sbjct: 754  QKALVDQLIIINQLSIKL-----INRRIITIKKRRFIEVLRYDWKWTLMSEKQQLQSDLR 808

Query: 1535 TLNDEITNLQNMVRASSS----KIQKHVSFASDTKQGRDEQLDNTMNKE 1579
             L  ++  +Q    A  S    K ++ +    D KQ    Q    ++ E
Sbjct: 809  MLQSKLDQIQQEQLALQSQLTQKTKQLIDIHDDVKQEEQIQQQQQLSNE 857



 Score = 68.1 bits (159), Expect = 2e-09
 Identities = 165/854 (19%), Positives = 365/854 (42%), Gaps = 94/854 (11%)

Query: 334  LNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSET 393
            L  Q+ Q  KEL+N  AT+    + +    ++          +  +   K  ++ L S+ 
Sbjct: 1531 LQAQLAQKQKELDNAQATLIQNQQIIDEQQQE----------QLKSEFWKKQYTDLISQQ 1580

Query: 394  LNQDTDKKINKNEIAKLEMVI----QSLNKDLVDK-EYVISEKDT--XXXXXXXXXXGKD 446
               D  K+I K + ++L   I    QS N +L ++   ++ E+ +            GK 
Sbjct: 1581 APADQQKQILKQKESELTQEIKQPSQSNNDNLQEQINNLLIERASLQQQLIQAQGKLGKA 1640

Query: 447  TLIAQLQLEHQQHMEGPSLIH-VGTNTEDVNE-IAKVQEQLKQELNDEIKDVNVKDLIEK 504
            T   +     QQ  +    I  +    +++ +    + EQ+K  L+ + +   +  LIEK
Sbjct: 1641 TQNLESTDSPQQGQDSQGQIQKLNREVQELQQRNQNLIEQMKSALSGDDQGQKLAQLIEK 1700

Query: 505  LKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTID-----NFS-KVSDSNKEIV 558
                    ++L  ++D   K ++K +  +++ +++++   D     N   +VSD  K+I 
Sbjct: 1701 NNQLSLNNSKLMIDLDVNQKELLKQQGQNQVLIEKVKDLSDPSVTENAKLRVSDLQKQID 1760

Query: 559  RLTEELHHLSQK----VAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRL- 613
             + +++    QK    + E  ++     +     +  + I       ++  +   +T+L 
Sbjct: 1761 LIGQQVDFWKQKYQQVLNEYSQQLSPTSIQRKMLEQAQYIHQQEEALLMLQQTTDQTKLD 1820

Query: 614  --KAISLLESQKFDLVQELHILQQKYDEVEDKLADISQ---LQSDQVCSEIK--SVHLEE 666
                I+ L  +   L  E   L+++  E E++   IS+   L  DQ   +I+      +E
Sbjct: 1821 NENQINQLRIENKILNDENVNLKKRIQEQENQSQQISRQHVLSQDQYDKQIQFWKEKYQE 1880

Query: 667  QIDALSASKKELALVI-------ENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMD 719
             + AL    +++  +I       +N++ DK+  +  I   ++   +I++KL++   EN  
Sbjct: 1881 ALQALHKDPQKVQDIIQQQEESAQNIQSDKD--WQPILKQQDQSSEIIDKLRS---ENQT 1935

Query: 720  LTDKLE--KMSAEKISELLAKINHEEQSKIQTQ----FGIDAKIQE--------RDLYIE 765
               ++   K    ++ +   K +  +Q  IQ+Q      +D  +Q+           Y +
Sbjct: 1936 FQGEVTFYKKRVFELEQQQQKPDPSQQDTIQSQQYQISQLDRDLQKALQTSAYWEQKYND 1995

Query: 766  NIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEY-----TIQE 820
             ++  ++K   +    + + +    +    E+   QL   +QEK++   ++     +I +
Sbjct: 1996 VVQQSINKEVGQRGDAQNTASYWRQKFDQAEQSRQQLMQVIQEKEEQIEQHMQSFQSILK 2055

Query: 821  DELVNRLAVLMDHDR-VVEKQLLEIE--HENKELQK-KNQILLEENQNLQISLSDMQQHY 876
            DEL   L  + + +R  +E QL + +  +E+  +QK K Q  +E+ Q +Q  L  + Q  
Sbjct: 2056 DELKEELTKIRNQERQKIELQLQQNQPYNESNLIQKLKEQHEVEKQQLIQEFLRRIDQLL 2115

Query: 877  NALVEK----ANRTDLAESESTKYQTQLRDLESNLKRITHEH-QTLIVQKKKEIEDLEIE 931
             + V+K     N  +L      + Q +L +L  +L+ +     QT  ++   E    E  
Sbjct: 2116 QSNVQKYPEGENWKELILRYEKQRQNELYELRQHLEILQRSQIQTKDIEFYAERRAYENA 2175

Query: 932  FNTQIESAIR--DKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELI 989
             N ++++ I+  D + L +  E   + +  LE Q+   +N   NL M++ +LN+  ++ +
Sbjct: 2176 IN-ELKNRIQQDDPQELYDTIEYQRKVILDLEDQVGFLQNERNNLEMHIMQLNQ-QIDQL 2233

Query: 990  DKHVQKQQTQSPDYTEQYINEINKLNALLKQK---DEEIIALNQKINNAQ--VSYMSMVS 1044
              ++ + Q QS +   Q    +  +  + +++    E   + ++++  +Q   S+     
Sbjct: 2234 KDNISRYQMQSDNRKRQRAEVLEAIEEMKRERARERESYKSPHRQMRQSQNRSSWDRYPK 2293

Query: 1045 DY-ESKLAQFTTKLENMEEEMQRV---SKQLLDSKQHNEELQILVREQDDQIKELKETKL 1100
            DY      Q  ++ +     MQR+     Q +  +Q N ++ +L  ++ D++K   +  L
Sbjct: 2294 DYLRPSNIQQPSQFQEHSSPMQRIPFQQSQFVSPQQENRDI-VLKLQELDEVKHKYQNAL 2352

Query: 1101 TFEMNIPKTEGMII 1114
                NI + E  +I
Sbjct: 2353 N---NILQLEAQVI 2363



 Score = 58.4 bits (135), Expect = 2e-06
 Identities = 112/593 (18%), Positives = 250/593 (42%), Gaps = 58/593 (9%)

Query: 394  LNQDTD--KKINKNEIAKLEMVIQSLNKDLVD-KEYVISEKDTXXXXXXXXXXGKDTLIA 450
            L Q TD  K  N+N+I +L +  + LN + V+ K+ +  +++            +D    
Sbjct: 1810 LQQTTDQTKLDNENQINQLRIENKILNDENVNLKKRIQEQENQSQQISRQHVLSQDQYDK 1869

Query: 451  QLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEE 510
            Q+Q   +++ E    +H   + + V +I + QE+  Q +     D + + ++++   + E
Sbjct: 1870 QIQFWKEKYQEALQALH--KDPQKVQDIIQQQEESAQNIQS---DKDWQPILKQQDQSSE 1924

Query: 511  QITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSK--VSDSNKEIVRLTEELHHLS 568
             I +L  E +   +  +        +L+Q Q+  D   +  +     +I +L  +L    
Sbjct: 1925 IIDKLRSE-NQTFQGEVTFYKKRVFELEQQQQKPDPSQQDTIQSQQYQISQLDRDLQKAL 1983

Query: 569  QKVAELEEEKGNLQLHLVDYDSGRMIESD---VYKKMIEMENLAETRLKAISLLESQKFD 625
            Q  A  E++  ++    ++ + G+  ++     Y +  + +   ++R + + +++ ++  
Sbjct: 1984 QTSAYWEQKYNDVVQQSINKEVGQRGDAQNTASYWRQ-KFDQAEQSRQQLMQVIQEKEEQ 2042

Query: 626  LVQELHILQQKY-DEVEDKLADIS---------QLQSDQVCSEIKSVH-LEEQIDALSAS 674
            + Q +   Q    DE++++L  I          QLQ +Q  +E   +  L+EQ +     
Sbjct: 2043 IEQHMQSFQSILKDELKEELTKIRNQERQKIELQLQQNQPYNESNLIQKLKEQHEVEKQQ 2102

Query: 675  K-KELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKIS 733
              +E    I+ L     Q Y    + EN KE I+   +    E  +L   LE +   +I 
Sbjct: 2103 LIQEFLRRIDQLLQSNVQKY---PEGENWKELILRYEKQRQNELYELRQHLEILQRSQIQ 2159

Query: 734  ELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRY 793
                +   E ++       +  +IQ+ D   + +   +   +  I  LE+ +  +++ R 
Sbjct: 2160 TKDIEFYAERRAYENAINELKNRIQQDDP--QELYDTIEYQRKVILDLEDQVGFLQNERN 2217

Query: 794  SLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQK 853
            +LE    QL   + + +   S Y +Q D   NR           ++Q  E+    +E+++
Sbjct: 2218 NLEMHIMQLNQQIDQLKDNISRYQMQSD---NR-----------KRQRAEVLEAIEEMKR 2263

Query: 854  KNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHE 913
            +      E ++ +     M+Q  N         D     + +  +Q ++  S ++RI  +
Sbjct: 2264 ER---ARERESYKSPHRQMRQSQNRSSWDRYPKDYLRPSNIQQPSQFQEHSSPMQRIPFQ 2320

Query: 914  HQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQE 966
             Q+  V  ++E  D+ ++        +++   +  KY+  +  + QLEAQ+ E
Sbjct: 2321 -QSQFVSPQQENRDIVLK--------LQELDEVKHKYQNALNNILQLEAQVIE 2364



 Score = 39.5 bits (88), Expect = 0.75
 Identities = 93/454 (20%), Positives = 188/454 (41%), Gaps = 49/454 (10%)

Query: 453  QLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIK-DVNVKDLIEKLKSAEEQ 511
            +LE QQ    PS     T      +I+++   L++ L      +    D++++  S  ++
Sbjct: 1949 ELEQQQQKPDPS--QQDTIQSQQYQISQLDRDLQKALQTSAYWEQKYNDVVQQ--SINKE 2004

Query: 512  ITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVR-LTEELHHLSQK 570
            + Q  D  + A+    K     + + + MQ   +   ++    +     L +EL     K
Sbjct: 2005 VGQRGDAQNTASYWRQKFDQAEQSRQQLMQVIQEKEEQIEQHMQSFQSILKDELKEELTK 2064

Query: 571  VAELEEEKGNLQLHLVD-YDSGRMIESDVYKKMIEMENLAETRLKAIS-LLES--QKFDL 626
            +   E +K  LQL     Y+   +I+    +  +E + L +  L+ I  LL+S  QK+  
Sbjct: 2065 IRNQERQKIELQLQQNQPYNESNLIQKLKEQHEVEKQQLIQEFLRRIDQLLQSNVQKYPE 2124

Query: 627  VQELHILQQKYDEV-EDKLADISQ----LQSDQVCSEIKSVHLEEQIDALSASKKELALV 681
             +    L  +Y++  +++L ++ Q    LQ  Q+  + K +    +  A   +  EL   
Sbjct: 2125 GENWKELILRYEKQRQNELYELRQHLEILQRSQI--QTKDIEFYAERRAYENAINELKNR 2182

Query: 682  IENLKLDKEQLYGTIK-------DLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISE 734
            I+  + D ++LY TI+       DLE+    + N+  N     M L  +++++  + IS 
Sbjct: 2183 IQ--QDDPQELYDTIEYQRKVILDLEDQVGFLQNERNNLEMHIMQLNQQIDQLK-DNISR 2239

Query: 735  LLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYS 794
               + ++ ++ + +    I+   +ER         E   YKS   ++ +S       R S
Sbjct: 2240 YQMQSDNRKRQRAEVLEAIEEMKRER-------ARERESYKSPHRQMRQS-----QNRSS 2287

Query: 795  LERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKK 854
             +R       YL+          IQ+       +  M      + Q +  + EN+++  K
Sbjct: 2288 WDRYPKD---YLRPSN-------IQQPSQFQEHSSPMQRIPFQQSQFVSPQQENRDIVLK 2337

Query: 855  NQILLEENQNLQISLSDMQQHYNALVEKANRTDL 888
             Q L E     Q +L+++ Q    ++EK  + D+
Sbjct: 2338 LQELDEVKHKYQNALNNILQLEAQVIEKLQQDDI 2371


>UniRef50_Q6CPF6 Cluster: Kluyveromyces lactis strain NRRL Y-1140
            chromosome E of strain NRRL Y- 1140 of Kluyveromyces
            lactis; n=1; Kluyveromyces lactis|Rep: Kluyveromyces
            lactis strain NRRL Y-1140 chromosome E of strain NRRL Y-
            1140 of Kluyveromyces lactis - Kluyveromyces lactis
            (Yeast) (Candida sphaerica)
          Length = 1755

 Score =  132 bits (320), Expect = 6e-29
 Identities = 217/1058 (20%), Positives = 469/1058 (44%), Gaps = 91/1058 (8%)

Query: 529  VKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNL-QLHL-- 585
            VK N K +    + TI+N + ++  N ++ +L++ L HL  +    E E   L + H   
Sbjct: 701  VKFN-KTRADLEKSTIENENVINSLNSKLEKLSKSLEHLETEKVNAETELNQLNERHSAL 759

Query: 586  -VDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEV-EDK 643
             V+ +  ++    V  K  ++E L +   KAI++ + Q     ++++ LQQK  E+ E K
Sbjct: 760  EVELNDTKIALESVNNKSQKLEELKQKNTKAIAVNQEQIDKYKEKINGLQQKVKEISESK 819

Query: 644  LA---DISQLQSDQVCSEIKSVHLEEQIDA----LSASKKELALVIENLKLDKEQLYGTI 696
            L     I+++  +      ++  L+E + +    L   +K+ +    NL+   ++    +
Sbjct: 820  LKAEDGINKMSRELFTLTKENGKLKEDLKSHSKKLEIQEKKYSSETANLEKQLKERGTEV 879

Query: 697  KDL-ENDKEDI--MNKLQNYI----QENMDLTDKLEKMSA--EKISELLAKINHEEQSKI 747
            ++L E   EDI  ++ L+  +     + ++L  KL   ++   K++E L  + +  +   
Sbjct: 880  QELRERISEDIKRIDTLEKNVTILSNQKIELETKLSNQTSLIPKLTEKLKGLANNYKDLE 939

Query: 748  QTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQ 807
              +  +  KI E++   + I   L+     + +  E + +  D +Y+ E    +  ++  
Sbjct: 940  NERDTLAKKILEKEEANKTIMQNLNSEIESLNKEREEMRL--DLQYAAEYHQKEKENFDA 997

Query: 808  EKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQI 867
              QK  SE   + + +++ L   +D     E+Q+ E +  N+EL+     L  +   L+ 
Sbjct: 998  HTQKLTSENNSKSESIIS-LQTKLDE---CERQIKEYKTTNEELKNSLHALNVKCIELES 1053

Query: 868  SLSDMQQ---HYNALVEKANRTDLAESESTKYQTQLRDLESNLK---RITHE---HQTLI 918
            SL   +Q   + +  +E+ N + +A ++  + Q+ L + +  LK   +I  E   +Q  +
Sbjct: 1054 SLESAKQSTDNSDETIEELNDSVIAIND--ELQSVLAEKDELLKQNNKINEELCNYQQEL 1111

Query: 919  VQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNV 978
             +K    + L+ + ++     ++  +  N+K +       +  A++++ K+ I N+  N 
Sbjct: 1112 QEKADSCQGLQDKISSLNNEIMQISEESNDKIKLLEASNEEKVAEIKDLKSEISNIKQNA 1171

Query: 979  E---ELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNA 1035
            +   E  K  ++ +   +   ++      + Y N    +  L + K++    + ++   A
Sbjct: 1172 DTKAEKLKSEIDALKSRISDLESLLETKNKLYENSQTTITELEQAKEKLQRTIQEQYKEA 1231

Query: 1036 QVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKEL 1095
            Q S  S+++  E+K+    ++LE +  ++  VSK+  ++   +EE++ +  E +D +K L
Sbjct: 1232 QYSEDSLLAG-ENKIKHLESQLEKL--KLSSVSKE-KEAHLKDEEIKSVKAEIEDNVK-L 1286

Query: 1096 KETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERS 1155
             + K T E++  K +  +++S +    + A                    + ++F +ER 
Sbjct: 1287 VQAKST-ELDELKKQNSVLNSKLNKEKEKAKIEQHKLRESLATARDELKSKIKDFEEERK 1345

Query: 1156 VLQEQSAKLNTELQECYTKIIQL-ETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLL 1214
            +L E S++LN +  E   KI++L ETLN     H+   Q+  N +++ LEQ   E+ + L
Sbjct: 1346 LLSEGSSELNQQYSE---KILKLEETLNNVKADHEKAVQKLENTIEA-LEQQAEESKSSL 1401

Query: 1215 STVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDS 1274
             T      S+SS   Q+  ++ ++         A+ QK   +L  +L+  +  +++  ++
Sbjct: 1402 DT----ERSLSSKEQQQRLQLEKIL--------ANEQKENKDLENKLADLDQLFKEHENT 1449

Query: 1275 VQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAF 1334
            ++S T+   +    +E+ + +  +L+  E  L++      + I + EIL S++ DE V  
Sbjct: 1450 LESQTKISQDYKQQLEKNSQVIEELKSAESALKDKLIAAEEKIKESEILTSQL-DEAVTS 1508

Query: 1335 XXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXR 1394
                            DL  +N   K   E  IL   +E ++ ++S              
Sbjct: 1509 TSALLEEQTKLKKSISDLEAKN--IKDCGEMEIL--RKELSKCQESLKVSQRLNEEKDEA 1564

Query: 1395 VNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYE 1454
                E  ++ L  ++     E+  K  E +         FE  +++++   K +E     
Sbjct: 1565 NKRTETDIVSLQKEINTLKEELRTKNDEISC--------FEADKKEMIAKLKELE----- 1611

Query: 1455 KESELAILRLKMHENANH-YETMQKESEIERVKL-IEELNVKITESVSL-NKQVAELNKA 1511
             ES+  ++     +NA    E      EI+ +KL +     K+  S  L + +  EL K 
Sbjct: 1612 -ESKTLLVHSAQEKNAQMIQENTSLAEEIKELKLQVNTWTEKLVTSEQLWSSEKTELIKQ 1670

Query: 1512 LEEEVAKTNEMQTALENQE--IEIVTLNDEITNLQNMV 1547
            +  ++ KT   + A EN +  +E+  + +E   L+N V
Sbjct: 1671 M--DIIKTESAKQAQENSQLNVELSAIKEENMKLKNRV 1706



 Score =  127 bits (306), Expect = 3e-27
 Identities = 226/1095 (20%), Positives = 463/1095 (42%), Gaps = 97/1095 (8%)

Query: 147  LSNTIKEKDNALSVLQVKMKIMETTILDLQ-EKINEKDQIIEAKNKATTXXXXXXXXXXX 205
            L  +  E +N ++ L  K++ +  ++  L+ EK+N + ++ +   + +            
Sbjct: 710  LEKSTIENENVINSLNSKLEKLSKSLEHLETEKVNAETELNQLNERHSALEVELNDTKIA 769

Query: 206  XXXXXXEDTK-QQMTKMQENFIAMEAEWKDEKQRLLKDIESK--DVRISSLEEANKLLEA 262
                  +  K +++ +     IA+  E  D+ +  +  ++ K  ++  S L+  + + + 
Sbjct: 770  LESVNNKSQKLEELKQKNTKAIAVNQEQIDKYKEKINGLQQKVKEISESKLKAEDGINKM 829

Query: 263  AR--FEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIAN 320
            +R  F ++ E+ KL ++L+                     +   E  TE++E        
Sbjct: 830  SRELFTLTKENGKLKEDLKSHSKKLEIQEKKYSSETANLEKQLKERGTEVQELRE----R 885

Query: 321  MTELTKKIELLEHLNCQIRQTNK-ELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTA 379
            ++E  K+I+ LE  N  I    K ELE KL+    ++  +   ++K       K   N  
Sbjct: 886  ISEDIKRIDTLEK-NVTILSNQKIELETKLSN---QTSLIPKLTEK------LKGLANNY 935

Query: 380  SKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXX 439
              +++    L+ + L ++   + NK  +  L   I+SLNK+   +E +  +         
Sbjct: 936  KDLENERDTLAKKILEKE---EANKTIMQNLNSEIESLNKE---REEMRLDLQYAAEYHQ 989

Query: 440  XXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVK 499
                  D    +L  E+    E  S+I + T  ++     K  +   +EL + +  +NVK
Sbjct: 990  KEKENFDAHTQKLTSENNSKSE--SIISLQTKLDECERQIKEYKTTNEELKNSLHALNVK 1047

Query: 500  --DLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEI 557
              +L   L+SA++     ++ I+  N ++I +    +  L +  + +   +K+   N+E+
Sbjct: 1048 CIELESSLESAKQSTDNSDETIEELNDSVIAINDELQSVLAEKDELLKQNNKI---NEEL 1104

Query: 558  VRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAIS 617
                +EL   +     L+++  +L   ++        ES+   K++E  N  E ++  I 
Sbjct: 1105 CNYQQELQEKADSCQGLQDKISSLNNEIMQISE----ESNDKIKLLEASN--EEKVAEIK 1158

Query: 618  LLESQKFDLVQELHILQQKY-DEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKK 676
             L+S+  ++ Q      +K   E++   + IS L+S          + +  I  L  +K+
Sbjct: 1159 DLKSEISNIKQNADTKAEKLKSEIDALKSRISDLESLLETKNKLYENSQTTITELEQAKE 1218

Query: 677  ELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELL 736
            +L   I+    + +    ++   EN  + + ++L+     ++   +K   +  E+I  + 
Sbjct: 1219 KLQRTIQEQYKEAQYSEDSLLAGENKIKHLESQLEKLKLSSVS-KEKEAHLKDEEIKSVK 1277

Query: 737  AKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYS-- 794
            A+I    +        +D   ++  +    +  E  K K    +L ES+A   D   S  
Sbjct: 1278 AEIEDNVKLVQAKSTELDELKKQNSVLNSKLNKEKEKAKIEQHKLRESLATARDELKSKI 1337

Query: 795  --LERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQ 852
               E +   L     E  + YSE  ++ +E +N   V  DH++ V+K    IE   ++ +
Sbjct: 1338 KDFEEERKLLSEGSSELNQQYSEKILKLEETLNN--VKADHEKAVQKLENTIEALEQQAE 1395

Query: 853  KKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLK--RI 910
            +    L  E      SLS  +Q     +EK    +  + E+   + +L DL+   K    
Sbjct: 1396 ESKSSLDTER-----SLSSKEQQQRLQLEKILANE--QKENKDLENKLADLDQLFKEHEN 1448

Query: 911  THEHQTLIVQK-KKEIE--DLEIEFNTQIESAIRDKKVLNEKYEKNIEYVT-QLEAQLQE 966
            T E QT I Q  K+++E     IE     ESA++DK +  E+  K  E +T QL+  +  
Sbjct: 1449 TLESQTKISQDYKQQLEKNSQVIEELKSAESALKDKLIAAEEKIKESEILTSQLDEAVTS 1508

Query: 967  YKNNIE---NLNMNVEELNKMN------LELIDKHVQKQQTQSPDYTEQYINEINKLNAL 1017
                +E    L  ++ +L   N      +E++ K + K Q +S   +++   E ++ N  
Sbjct: 1509 TSALLEEQTKLKKSISDLEAKNIKDCGEMEILRKELSKCQ-ESLKVSQRLNEEKDEAN-- 1565

Query: 1018 LKQKDEEIIALNQKINNAQVSYMSM---VSDYESKLAQFTTKLENMEEEMQRVSKQLLDS 1074
             K+ + +I++L ++IN  +    +    +S +E+   +   KL+ +EE     SK LL  
Sbjct: 1566 -KRTETDIVSLQKEINTLKEELRTKNDEISCFEADKKEMIAKLKELEE-----SKTLLVH 1619

Query: 1075 KQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXX 1134
                +  Q +++E     +E+KE KL  ++N   TE ++ S  +   S +   +      
Sbjct: 1620 SAQEKNAQ-MIQENTSLAEEIKELKL--QVN-TWTEKLVTSEQL--WSSEKTEL-IKQMD 1672

Query: 1135 XXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQE 1194
                    + QE  +   E S ++E++ KL   + +  +++  L  L T+L        E
Sbjct: 1673 IIKTESAKQAQENSQLNVELSAIKEENMKLKNRVDD-RSEVDDLVILVTDL-------DE 1724

Query: 1195 QINQLKSKLEQLNTE 1209
            Q ++ K KL +L  E
Sbjct: 1725 QKSKYKRKLIELGVE 1739



 Score =  121 bits (292), Expect = 1e-25
 Identities = 203/1027 (19%), Positives = 427/1027 (41%), Gaps = 91/1027 (8%)

Query: 627  VQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLK 686
            ++  +++     ++E     +  L++++V +E +   L E+  AL     +  + +E++ 
Sbjct: 715  IENENVINSLNSKLEKLSKSLEHLETEKVNAETELNQLNERHSALEVELNDTKIALESVN 774

Query: 687  LDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSK 746
               ++L           E++  K    I  N +  DK +    EKI+ L  K+    +SK
Sbjct: 775  NKSQKL-----------EELKQKNTKAIAVNQEQIDKYK----EKINGLQQKVKEISESK 819

Query: 747  IQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYL 806
            ++ + GI+     R+L+   +  E  K K  +    + + + E ++YS E     L   L
Sbjct: 820  LKAEDGINK--MSRELF--TLTKENGKLKEDLKSHSKKLEIQE-KKYSSETA--NLEKQL 872

Query: 807  QEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQ 866
            +E+     E   +  E + R+  L  +  ++  Q +E+E +          L E+ + L 
Sbjct: 873  KERGTEVQELRERISEDIKRIDTLEKNVTILSNQKIELETKLSNQTSLIPKLTEKLKGLA 932

Query: 867  ISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQT--LIVQKKKE 924
             +  D++   + L +K     L + E+ K  T +++L S ++ +  E +   L +Q   E
Sbjct: 933  NNYKDLENERDTLAKKI----LEKEEANK--TIMQNLNSEIESLNKEREEMRLDLQYAAE 986

Query: 925  IEDLEIE-FNTQIESAIRDKKVLNEKYEKNIEYVTQL---EAQLQEYKNNIENLNMNVEE 980
                E E F+   +    +    N K E  I   T+L   E Q++EYK   E L  ++  
Sbjct: 987  YHQKEKENFDAHTQKLTSEN---NSKSESIISLQTKLDECERQIKEYKTTNEELKNSLHA 1043

Query: 981  LNKMNLELIDK-HVQKQQTQSPDYTEQYINE----IN-KLNALLKQKDEEIIALNQKINN 1034
            LN   +EL       KQ T + D T + +N+    IN +L ++L +KDE ++  N KIN 
Sbjct: 1044 LNVKCIELESSLESAKQSTDNSDETIEELNDSVIAINDELQSVLAEKDE-LLKQNNKINE 1102

Query: 1035 AQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDS----KQHNEELQILVREQDD 1090
               +Y   + +          K+ ++  E+ ++S++  D     +  NEE    +++   
Sbjct: 1103 ELCNYQQELQEKADSCQGLQDKISSLNNEIMQISEESNDKIKLLEASNEEKVAEIKDLKS 1162

Query: 1091 QIKELKET------KLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLK- 1143
            +I  +K+       KL  E++  K+    + S +E  +    N              L+ 
Sbjct: 1163 EISNIKQNADTKAEKLKSEIDALKSRISDLESLLETKNKLYENSQTTITELEQAKEKLQR 1222

Query: 1144 -VQEEEEFIQ--ERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLK 1200
             +QE+ +  Q  E S+L  ++   + E Q    + ++L +++ E   H  +  E+I  +K
Sbjct: 1223 TIQEQYKEAQYSEDSLLAGENKIKHLESQ---LEKLKLSSVSKEKEAH--LKDEEIKSVK 1277

Query: 1201 SKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQ 1260
            +++E  N +     ST  +     +S ++ +  +  E  K    +          EL+ +
Sbjct: 1278 AEIED-NVKLVQAKSTELDELKKQNSVLNSKLNKEKEKAKIEQHKLRESLATARDELKSK 1336

Query: 1261 LSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQI 1320
            +  FE + + L +      Q+ + KI+ +E+  +L N   D E+ ++ L+     +  Q 
Sbjct: 1337 IKDFEEERKLLSEGSSELNQQYSEKILKLEE--TLNNVKADHEKAVQKLENTIEALEQQA 1394

Query: 1321 EILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSIL-----NINEENA 1375
            E  +S ++ E+                   + +       ++ +   L     N  E   
Sbjct: 1395 EESKSSLDTERSLSSKEQQQRLQLEKILANEQKENKDLENKLADLDQLFKEHENTLESQT 1454

Query: 1376 QLKKSSXXXXXXXXXXXXRVNDAEAKVLE--LTHQLELKDSEIYQKTHEYTITLTQRN-D 1432
            ++ +               +  AE+ + +  +  + ++K+SEI     +  +T T    +
Sbjct: 1455 KISQDYKQQLEKNSQVIEELKSAESALKDKLIAAEEKIKESEILTSQLDEAVTSTSALLE 1514

Query: 1433 EFENVRQQLVEYE-KRIEDL----TYEKESELAILRLKMHENANHY-ETMQKESEIERVK 1486
            E   +++ + + E K I+D        KE       LK+ +  N   +   K +E + V 
Sbjct: 1515 EQTKLKKSISDLEAKNIKDCGEMEILRKELSKCQESLKVSQRLNEEKDEANKRTETDIVS 1574

Query: 1487 LIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQ---TAL------ENQEI--EIVT 1535
            L +E+N    E  + N +++      +E +AK  E++   T L      +N ++  E  +
Sbjct: 1575 LQKEINTLKEELRTKNDEISCFEADKKEMIAKLKELEESKTLLVHSAQEKNAQMIQENTS 1634

Query: 1536 LNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDLAMYM 1595
            L +EI  L+  V   + K+       S  K    +Q+D    +    A   ++L++ +  
Sbjct: 1635 LAEEIKELKLQVNTWTEKLVTSEQLWSSEKTELIKQMDIIKTESAKQAQENSQLNVELSA 1694

Query: 1596 LHQRDVR 1602
            + + +++
Sbjct: 1695 IKEENMK 1701



 Score =  107 bits (258), Expect = 2e-21
 Identities = 204/1060 (19%), Positives = 444/1060 (41%), Gaps = 94/1060 (8%)

Query: 464  SLIHVGT---NTE-DVNEIAKVQEQLKQELND-EIKDVNVKDLIEKLKSAEEQITQLNDE 518
            SL H+ T   N E ++N++ +    L+ ELND +I   +V +  +KL    E++ Q N +
Sbjct: 734  SLEHLETEKVNAETELNQLNERHSALEVELNDTKIALESVNNKSQKL----EELKQKNTK 789

Query: 519  IDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEK 578
              A N+  I     +K K+  +Q+      KV + ++  ++  + ++ +S+++  L +E 
Sbjct: 790  AIAVNQEQI---DKYKEKINGLQQ------KVKEISESKLKAEDGINKMSRELFTLTKEN 840

Query: 579  GNLQLHLVDYDSGRMIESDVYK-KMIEMENLAETRLKAISLLESQKFDLVQELHILQQKY 637
            G L+  L  +     I+   Y  +   +E   + R   +  L  +  + ++ +  L++  
Sbjct: 841  GKLKEDLKSHSKKLEIQEKKYSSETANLEKQLKERGTEVQELRERISEDIKRIDTLEKNV 900

Query: 638  DEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLK---LDKEQLYG 694
              + ++  ++    S+Q     K   L E++  L+ + K+L    + L    L+KE+   
Sbjct: 901  TILSNQKIELETKLSNQTSLIPK---LTEKLKGLANNYKDLENERDTLAKKILEKEEANK 957

Query: 695  TIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGID 754
            TI    N + + +NK +  ++ ++    +  +   E       K+  E  SK ++   + 
Sbjct: 958  TIMQNLNSEIESLNKEREEMRLDLQYAAEYHQKEKENFDAHTQKLTSENNSKSESIISLQ 1017

Query: 755  AKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYS 814
             K+ E +  I+  ++   + K+ +  L      +E    S ++  D     ++E   +  
Sbjct: 1018 TKLDECERQIKEYKTTNEELKNSLHALNVKCIELESSLESAKQSTDNSDETIEELNDSVI 1077

Query: 815  EYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQ 874
                  DEL    +VL + D ++ KQ  +I  E    Q++ Q   +  Q LQ  +S +  
Sbjct: 1078 AI---NDEL---QSVLAEKDELL-KQNNKINEELCNYQQELQEKADSCQGLQDKISSLNN 1130

Query: 875  HYNALVEKAN-RTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFN 933
                + E++N +  L E+ + +   +++DL+S +  I     T   + K EI+ L+    
Sbjct: 1131 EIMQISEESNDKIKLLEASNEEKVAEIKDLKSEISNIKQNADTKAEKLKSEIDALKSRI- 1189

Query: 934  TQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQ-----EYK-------------NNIENLN 975
            + +ES +  K  L E  +  I  + Q + +LQ     +YK             N I++L 
Sbjct: 1190 SDLESLLETKNKLYENSQTTITELEQAKEKLQRTIQEQYKEAQYSEDSLLAGENKIKHLE 1249

Query: 976  MNVEEL------NKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALN 1029
              +E+L       +    L D+ ++  + +  D  +    +  +L+ L KQ       LN
Sbjct: 1250 SQLEKLKLSSVSKEKEAHLKDEEIKSVKAEIEDNVKLVQAKSTELDELKKQNSVLNSKLN 1309

Query: 1030 QKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQD 1089
            ++   A++    +     +   +  +K+++ EEE + +S+   +  Q   E +IL  E+ 
Sbjct: 1310 KEKEKAKIEQHKLRESLATARDELKSKIKDFEEERKLLSEGSSELNQQYSE-KILKLEE- 1367

Query: 1090 DQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEE 1149
                 L   K   E  + K E     +TIE +   A                L  +E+++
Sbjct: 1368 ----TLNNVKADHEKAVQKLE-----NTIEALEQQAEE----SKSSLDTERSLSSKEQQQ 1414

Query: 1150 FIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQ-LKSKLEQLNT 1208
             +Q   +L  +  K N +L+    K+  L+ L  E   + + +Q +I+Q  K +LE+ + 
Sbjct: 1415 RLQLEKILANEQ-KENKDLE---NKLADLDQLFKE-HENTLESQTKISQDYKQQLEKNSQ 1469

Query: 1209 ENDNLLSTVAELRSSISSAVDQ-RGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESK 1267
              + L S  + L+  + +A ++ +  EI            +   + + +L+  +S  E+K
Sbjct: 1470 VIEELKSAESALKDKLIAAEEKIKESEILTSQLDEAVTSTSALLEEQTKLKKSISDLEAK 1529

Query: 1268 YEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEI 1327
              +    ++   ++E +K    E +   Q   ++K+E  +  +     +  +I  L+ E+
Sbjct: 1530 NIKDCGEME-ILRKELSK--CQESLKVSQRLNEEKDEANKRTETDIVSLQKEINTLKEEL 1586

Query: 1328 EDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXX 1387
              +                       ++       QE++   I +EN  L +        
Sbjct: 1587 RTKNDEISCFEADKKEMIAKLKELEESKTLLVHSAQEKNAQMI-QENTSLAEEIKELKLQ 1645

Query: 1388 XXXXXXRVNDAE----AKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVE 1443
                  ++  +E    ++  EL  Q+++  +E  ++  E     +Q N E   ++++ ++
Sbjct: 1646 VNTWTEKLVTSEQLWSSEKTELIKQMDIIKTESAKQAQEN----SQLNVELSAIKEENMK 1701

Query: 1444 YEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIE 1483
             + R++D +  +  +L IL   + E  + Y+    E  +E
Sbjct: 1702 LKNRVDDRS--EVDDLVILVTDLDEQKSKYKRKLIELGVE 1739



 Score = 71.7 bits (168), Expect = 2e-10
 Identities = 127/673 (18%), Positives = 283/673 (42%), Gaps = 55/673 (8%)

Query: 143  DVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXX 202
            ++ +    ++EK ++   LQ K+  +   I+ + E+ N+K +++EA N+           
Sbjct: 1103 ELCNYQQELQEKADSCQGLQDKISSLNNEIMQISEESNDKIKLLEASNEEKV-------- 1154

Query: 203  XXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEA 262
                     +D K +++ +++N     A+ K EK  L  +I++   RIS LE    LLE 
Sbjct: 1155 ------AEIKDLKSEISNIKQN-----ADTKAEK--LKSEIDALKSRISDLE---SLLE- 1197

Query: 263  ARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEE-KGSLEIANM 321
             + ++         ELEQ               A+ S +     + +I+  +  LE   +
Sbjct: 1198 TKNKLYENSQTTITELEQAKEKLQRTIQEQYKEAQYSEDSLLAGENKIKHLESQLEKLKL 1257

Query: 322  TELTKKIELLEHL-NCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTAS 380
            + ++K+ E   HL + +I+    E+E+ +  +  +S  +    K+ S L S+ +     +
Sbjct: 1258 SSVSKEKE--AHLKDEEIKSVKAEIEDNVKLVQAKSTELDELKKQNSVLNSKLNKEKEKA 1315

Query: 381  KMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXX 440
            K++    + S  T   +   KI   E  +  +   S   +    E ++  ++T       
Sbjct: 1316 KIEQHKLRESLATARDELKSKIKDFEEERKLLSEGSSELNQQYSEKILKLEETLNNVKAD 1375

Query: 441  XXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQ-EQLKQELNDEIKDVNVK 499
                   L   ++   QQ  E  S +    +     +  ++Q E++      E KD+  K
Sbjct: 1376 HEKAVQKLENTIEALEQQAEESKSSLDTERSLSSKEQQQRLQLEKILANEQKENKDLENK 1435

Query: 500  DL-IEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTI-DNFSKVSDSNKEI 557
               +++L    E   +   +I    K  ++  S    +LK  +  + D      +  KE 
Sbjct: 1436 LADLDQLFKEHENTLESQTKISQDYKQQLEKNSQVIEELKSAESALKDKLIAAEEKIKES 1495

Query: 558  VRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMI---ESDVYKKMIE--------ME 606
              LT +L       + L EE+  L+  + D ++  +    E ++ +K +          +
Sbjct: 1496 EILTSQLDEAVTSTSALLEEQTKLKKSISDLEAKNIKDCGEMEILRKELSKCQESLKVSQ 1555

Query: 607  NLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSD--QVCSEIKSVHL 664
             L E + +A    E+    L +E++ L+   +E+  K  +IS  ++D  ++ +++K +  
Sbjct: 1556 RLNEEKDEANKRTETDIVSLQKEINTLK---EELRTKNDEISCFEADKKEMIAKLKELEE 1612

Query: 665  EEQIDALSASKKELALVIENLKLDKE--QL---YGTIKDLENDKEDIMNKLQNYIQENMD 719
             + +   SA +K   ++ EN  L +E  +L     T  +     E + +  +  + + MD
Sbjct: 1613 SKTLLVHSAQEKNAQMIQENTSLAEEIKELKLQVNTWTEKLVTSEQLWSSEKTELIKQMD 1672

Query: 720  LTDKLEKMSAEKISELLAKIN--HEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSR 777
            +        A++ S+L  +++   EE  K++ +    +++ +  + + +++ + SKYK +
Sbjct: 1673 IIKTESAKQAQENSQLNVELSAIKEENMKLKNRVDDRSEVDDLVILVTDLDEQKSKYKRK 1732

Query: 778  ICRLEESIAVMED 790
            +  L   ++  E+
Sbjct: 1733 LIELGVELSSDEE 1745



 Score = 54.4 bits (125), Expect = 2e-05
 Identities = 67/379 (17%), Positives = 161/379 (42%), Gaps = 26/379 (6%)

Query: 1195 QINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEI--AELWKQHLAQREADFQK 1252
            + N+ ++ LE+   EN+N+++++      +S +++    E   AE     L +R +  + 
Sbjct: 702  KFNKTRADLEKSTIENENVINSLNSKLEKLSKSLEHLETEKVNAETELNQLNERHSALEV 761

Query: 1253 TEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQE- 1311
              ++ ++ L +  +K ++L +  Q +T+      V  EQ+   + K+   ++ ++ + E 
Sbjct: 762  ELNDTKIALESVNNKSQKLEELKQKNTKAIA---VNQEQIDKYKEKINGLQQKVKEISES 818

Query: 1312 --KYADVINQI--EILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQS- 1366
              K  D IN++  E+     E+ K+                     T N   KQ++E+  
Sbjct: 819  KLKAEDGINKMSRELFTLTKENGKLKEDLKSHSKKLEIQEKKYSSETANLE-KQLKERGT 877

Query: 1367 -ILNINEENAQ-------LKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQ 1418
             +  + E  ++       L+K+             ++++  + + +LT +L+   +  Y+
Sbjct: 878  EVQELRERISEDIKRIDTLEKNVTILSNQKIELETKLSNQTSLIPKLTEKLKGLANN-YK 936

Query: 1419 KTHEYTITLTQRNDEFENVRQQLVE-YEKRIEDLTYEKESELAILRLKMHENANHYETMQ 1477
                   TL ++  E E   + +++     IE L  E+E     +RL +   A +++  +
Sbjct: 937  DLENERDTLAKKILEKEEANKTIMQNLNSEIESLNKEREE----MRLDLQYAAEYHQKEK 992

Query: 1478 KESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLN 1537
            +  +    KL  E N K    +SL  ++ E  + ++E      E++ +L    ++ + L 
Sbjct: 993  ENFDAHTQKLTSENNSKSESIISLQTKLDECERQIKEYKTTNEELKNSLHALNVKCIELE 1052

Query: 1538 DEITNLQNMVRASSSKIQK 1556
              + + +     S   I++
Sbjct: 1053 SSLESAKQSTDNSDETIEE 1071



 Score = 46.4 bits (105), Expect = 0.007
 Identities = 79/445 (17%), Positives = 174/445 (39%), Gaps = 38/445 (8%)

Query: 1170 ECYTKI-IQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAV 1228
            E Y K+ ++      +L    + N+  IN L SKLE+L+   ++L +      + ++   
Sbjct: 694  ELYEKLYVKFNKTRADLEKSTIENENVINSLNSKLEKLSKSLEHLETEKVNAETELNQLN 753

Query: 1229 DQRGFEIAELWKQHLAQREAD--FQKTEHELRVQLSAFE------SKYEQLLDSVQSSTQ 1280
            ++      EL    +A    +   QK E   +    A         KY++ ++ +Q   +
Sbjct: 754  ERHSALEVELNDTKIALESVNNKSQKLEELKQKNTKAIAVNQEQIDKYKEKINGLQQKVK 813

Query: 1281 E-ETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXX 1339
            E   +K+   + +  +  +L    +    L+E       ++EI   +   E  A      
Sbjct: 814  EISESKLKAEDGINKMSRELFTLTKENGKLKEDLKSHSKKLEIQEKKYSSE-TANLEKQL 872

Query: 1340 XXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAE 1399
                       +  +E+       E+++  ++ +  +L+               ++    
Sbjct: 873  KERGTEVQELRERISEDIKRIDTLEKNVTILSNQKIELETKLSNQTSLIPKLTEKLKGLA 932

Query: 1400 AKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTY------ 1453
                +L ++ +    +I +K       +   N E E++ ++    E R+ DL Y      
Sbjct: 933  NNYKDLENERDTLAKKILEKEEANKTIMQNLNSEIESLNKE--REEMRL-DLQYAAEYHQ 989

Query: 1454 -EKESELAILRLKMHENANHYETM----QKESEIER-VKLIEELNVKITESV-SLNKQVA 1506
             EKE+  A  +    EN +  E++     K  E ER +K  +  N ++  S+ +LN +  
Sbjct: 990  KEKENFDAHTQKLTSENNSKSESIISLQTKLDECERQIKEYKTTNEELKNSLHALNVKCI 1049

Query: 1507 ELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNL----------QNMVRASSSKIQK 1556
            EL  +LE     T+     +E     ++ +NDE+ ++           N +       Q+
Sbjct: 1050 ELESSLESAKQSTDNSDETIEELNDSVIAINDELQSVLAEKDELLKQNNKINEELCNYQQ 1109

Query: 1557 HVSFASDTKQGRDEQLDNTMNKELL 1581
             +   +D+ QG  +++ +++N E++
Sbjct: 1110 ELQEKADSCQGLQDKI-SSLNNEIM 1133


>UniRef50_UPI0000E48979 Cluster: PREDICTED: similar to kinesin-related
            protein; n=3; Strongylocentrotus purpuratus|Rep:
            PREDICTED: similar to kinesin-related protein -
            Strongylocentrotus purpuratus
          Length = 2537

 Score =  132 bits (319), Expect = 8e-29
 Identities = 249/1291 (19%), Positives = 549/1291 (42%), Gaps = 114/1291 (8%)

Query: 342  NKELENKLATMGTES--KAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLS-SETLNQDT 398
            N +++++L +M T++  +A+++  K    L   ++  ++A++ +  + ++  SE     T
Sbjct: 807  NADIKSRLGSMETDALTEAMTTLEKSHKELAVLQAALDSANQEREAFGEVHISENSQLRT 866

Query: 399  DKKINKNEIAKLEMVIQS-----LNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQ 453
            + +    E+  L+   +      LN+ L   E   ++              K+TL  + +
Sbjct: 867  ELESASRELHSLKEQYEERDTTRLNEALATLEKQAADLTELQAALEISRGEKETLERRSE 926

Query: 454  LEHQQHMEG-PSLIHVGTNTEDVNEIAKVQEQLKQE---LNDEIKDVNVKDLIEKLKSAE 509
                  +    + +     ++ V E+  V E L +E   L D ++++  KD+ +      
Sbjct: 927  EMPSSDLNDIKATLESSQQSDQVREMQVVLETLTEENAALKDRLEELQTKDVNQVQVEEP 986

Query: 510  EQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDS-NKEIVRLTEELHHLS 568
            E+I  +  E++ ++     ++        ++ +TI + ++ + + + ++ +L  EL    
Sbjct: 987  EEILVMRAELEMSSALCDALQEEKDQLQTKLDETIPDAAQATQTPHPDVDKLKGELMESL 1046

Query: 569  QKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEM-ENLAETRL----KAISLLESQK 623
                 L EEK  L   L +      + +D    +I+M E +AE R     KA    E Q+
Sbjct: 1047 TLCEALNEEKNQLHSKLEETRKEIEMRTDESSDIIKMKEEIAELRFVLLQKAEEYAELQQ 1106

Query: 624  FDLVQ-------------ELHILQQKYDEVEDKLADI-SQLQSDQVCSEIKSVHLEEQID 669
            F   +             E++ LQ+   + +  L DI +++ +    SE +   L+ Q+D
Sbjct: 1107 FTRWEDKSLKEQESEYQCEINRLQEIMKQKDKDLRDIETKITAQLTQSENEKTDLDFQLD 1166

Query: 670  ALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSA 729
            A    K+    +   L+   ++ Y  +K+ E  +     +      E  +   +LE   A
Sbjct: 1167 A---EKERNRSMTSELRQQLQEAYDRLKEKEGAEGASAEEGMELETEKRENVVELEVRLA 1223

Query: 730  EKISE---LLAKINHEEQSKIQTQFGIDAKIQERDLY----IENIESELSKYKSRICRLE 782
            E + E   L  K + +E+   + +  +   +QE++      +  +ES L+     I  L+
Sbjct: 1224 EVLREMESLREKESQKEEMVTELETKLAGALQEKENVEEKKVHELESRLASILMEIEALK 1283

Query: 783  ESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELV---NRL-AVLMDHDRVVE 838
            +   V E++   LE K   L + +QE      E T++E ++V   +RL  VL + D   E
Sbjct: 1284 KEKTVREEKVCDLEAK---LANAVQEIDTLREEETLKEQKMVELESRLNMVLQEQDGEKE 1340

Query: 839  KQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQT 898
            ++LLE+  +   L ++ + L EE    +  +++++    +  E+    DL E    + ++
Sbjct: 1341 EKLLELSSKLANLLQETEELREEKNFKEERIAELESLLGSAPEED--VDLKEERVMELES 1398

Query: 899  QLRDL--------------ESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKK 944
             L ++              +  +  +      ++  K+   ED   E   Q+ S +++ +
Sbjct: 1399 HLANVLEETDSLRKAEAWKDERISELESRLGEVVNDKESGAEDKATELEAQLASVLQEVE 1458

Query: 945  VLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYT 1004
             L E+     E +++LE++L   + + E        + K + +L D  +Q+      + T
Sbjct: 1459 ALREEKNVKEEQISELESRLANVQQDKEGEEEG--RVVKQDSQLSDA-LQELDAMKEELT 1515

Query: 1005 EQYINEINKLNALLKQKDEEIIALNQK--INNAQV----SYMSMVS---DYESKLAQFTT 1055
             +   +I +L + L    +EI  L Q+  +  AQ+    S +++VS     E K+A+  +
Sbjct: 1516 LRE-EKIAQLESWLTTGMQEIEVLRQEKDVREAQMTELESRLAIVSKEISEEGKVAELES 1574

Query: 1056 KLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIIS 1115
             L N+  EM  + ++   +K    EL+  +     +++ LKE K   +  I   E  + S
Sbjct: 1575 HLTNVVGEMDSLREEKNLNKDKVAELESDLASVVQELEALKEEKNLKDEEISDLEARLTS 1634

Query: 1116 STIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKI 1175
             + E  +++   V+              ++EE+    E+  + +  A+LN++ QE   + 
Sbjct: 1635 ESQEKSAEEDKVVELESDLASVVQELEALKEEKNLKDEQ--ISDLEARLNSDSQEKSAEE 1692

Query: 1176 IQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGF-- 1233
             ++  L + LTG   V QE        LE L  E +  +    E++S ++ A  +  F  
Sbjct: 1693 EKVVELESHLTG---VLQE--------LEALKEEKNQKVGKFLEMQSHLNDARQELEFLN 1741

Query: 1234 EIAELWKQHLAQREADFQKTEHELRV----QLSAFESKYEQLLDSVQSSTQEETNKIVTM 1289
            E   L ++ +A+ ++ F     E  +    +++  ESK   +L  +++  + +  +   M
Sbjct: 1742 EDKNLREEQMAELKSRFANVSQEQDIFREEKVAEAESKLANVLQEIEALKEGKNLREQHM 1801

Query: 1290 EQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXX 1349
             ++ ++   +  +++ +R  +EK  ++ +++  +  E++  KV                 
Sbjct: 1802 AELEAMLAHVSQEQDTVR--EEKVLELESRLSCVLQEMDTLKVEETLKEAKATELETRHS 1859

Query: 1350 XDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQL 1409
              L       +++Q++ +  I +E A+L+ ++             V   E +  E   ++
Sbjct: 1860 EVL----NDMERLQDE-LTRIKDEKARLEAANYEIMSQMQKD---VVTMETQTEEDVAEV 1911

Query: 1410 ELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHEN 1469
            E +  +++    +    LT ++ E   V+ Q      R+E+L    E E      ++   
Sbjct: 1912 E-QSHDLHAAIEKLRKVLTSKDQEICEVKAQSSHEMGRLEELQQCLEEESREREERITAE 1970

Query: 1470 ANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQ 1529
              + E  +   E   VK   EL   I+E+  L +++    + +E  +A+  E  +AL  Q
Sbjct: 1971 LRNLEAEKTRLEAALVKAELELGDSISETCLLKEEM----EMMESRLAEGRE--SALGQQ 2024

Query: 1530 EIEIVTLNDEITNLQNMVRASSSKIQKHVSF 1560
            + E+  L  E+ + +N++     +I+K   F
Sbjct: 2025 QQEMEELMVELDSARNLLSQKEDEIEKLQEF 2055



 Score =  116 bits (280), Expect = 4e-24
 Identities = 235/1177 (19%), Positives = 491/1177 (41%), Gaps = 131/1177 (11%)

Query: 476  NEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAE---EQITQLNDEIDAANKNMIKVKSN 532
            + I++ Q +   EL   +   N++    K + AE    Q T + D ++AAN   I+V  N
Sbjct: 609  SHISESQNKELMELQAALDSANLEKAELKSRMAEIQEGQQTGMQDALNAANLE-IEVLKN 667

Query: 533  H--KLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDS 590
            H  + + K++ +        + +N E++    E+    Q   E++   G+  L   +  S
Sbjct: 668  HVSESQNKELMELQAALDTANLANAELMSRMAEIEKEQQ--TEIQAALGSANLENAELKS 725

Query: 591  GRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQL 650
              ++     K+++E+++   T    I +L++     VQ   +++ +       + D + L
Sbjct: 726  --LMAEQQNKQLMELQDALNTANLEIEVLKNHMTQ-VQNEQLMETQ------AVLDAANL 776

Query: 651  QSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDK-EDIMNK 709
            +++    E+KS HL    D  +    EL   ++    +   +   +  +E D   + M  
Sbjct: 777  ENE----ELKS-HLA---DVQNKQLMELQAALDLANAENADIKSRLGSMETDALTEAMTT 828

Query: 710  LQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQF--------GIDAKIQERD 761
            L+   +E   L   L+  + E+  E   +++  E S+++T+          +  + +ERD
Sbjct: 829  LEKSHKELAVLQAALDSANQER--EAFGEVHISENSQLRTELESASRELHSLKEQYEERD 886

Query: 762  LY-IENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQE 820
               +    + L K  + +  L+ ++ +    + +LER+++++ S      KA  E + Q 
Sbjct: 887  TTRLNEALATLEKQAADLTELQAALEISRGEKETLERRSEEMPSSDLNDIKATLESSQQS 946

Query: 821  DELVNRLAVLMDHDRVVEKQLLEIEHENKELQKK--NQILLEENQNLQISLSDMQQHYNA 878
            D+ V  + V+++    + ++   ++   +ELQ K  NQ+ +EE + + +  ++++   +A
Sbjct: 947  DQ-VREMQVVLE---TLTEENAALKDRLEELQTKDVNQVQVEEPEEILVMRAELEMS-SA 1001

Query: 879  LVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIES 938
            L       D  + E  + QT+L +   +  + T      + + K E+    +E  T  E+
Sbjct: 1002 LC------DALQEEKDQLQTKLDETIPDAAQATQTPHPDVDKLKGEL----MESLTLCEA 1051

Query: 939  AIRDKKVLNEKYE---KNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQK 995
               +K  L+ K E   K IE  T   + + + K  I  L   + +  +   EL  +  + 
Sbjct: 1052 LNEEKNQLHSKLEETRKEIEMRTDESSDIIKMKEEIAELRFVLLQKAEEYAEL-QQFTRW 1110

Query: 996  QQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSY---------------- 1039
            +     +   +Y  EIN+L  ++KQKD+++  +  KI  AQ++                 
Sbjct: 1111 EDKSLKEQESEYQCEINRLQEIMKQKDKDLRDIETKI-TAQLTQSENEKTDLDFQLDAEK 1169

Query: 1040 ---MSMVSDYESKLAQFTTKL---ENMEEEMQRVSKQLLDSKQHN-EELQILVREQDDQI 1092
                SM S+   +L +   +L   E  E        +L   K+ N  EL++ + E   ++
Sbjct: 1170 ERNRSMTSELRQQLQEAYDRLKEKEGAEGASAEEGMELETEKRENVVELEVRLAEVLREM 1229

Query: 1093 KELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQ 1152
            + L+E +   E  + + E  +  +  E  + +   V             ++  ++E+ ++
Sbjct: 1230 ESLREKESQKEEMVTELETKLAGALQEKENVEEKKVHELESRLASILMEIEALKKEKTVR 1289

Query: 1153 ERSVLQEQSAKLNTELQECYT----------KIIQLET-LNTELTGHDVVNQEQINQLKS 1201
            E  V  +  AKL   +QE  T          K+++LE+ LN  L   D   +E++ +L S
Sbjct: 1290 EEKVC-DLEAKLANAVQEIDTLREEETLKEQKMVELESRLNMVLQEQDGEKEEKLLELSS 1348

Query: 1202 KL-------EQLNTENDNLLSTVAELRSSISSA----VDQRGFEIAELWKQHLAQ--REA 1248
            KL       E+L  E +     +AEL S + SA    VD +   + EL + HLA    E 
Sbjct: 1349 KLANLLQETEELREEKNFKEERIAELESLLGSAPEEDVDLKEERVMEL-ESHLANVLEET 1407

Query: 1249 D-FQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKI-----VTMEQVTSLQNKLQDK 1302
            D  +K E     ++S  ES+  ++++  +S  +++  ++       +++V +L+ +   K
Sbjct: 1408 DSLRKAEAWKDERISELESRLGEVVNDKESGAEDKATELEAQLASVLQEVEALREEKNVK 1467

Query: 1303 EEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQM 1362
            EE +  L+ + A+V    E    E E   V                  +L    +   Q+
Sbjct: 1468 EEQISELESRLANVQQDKE---GEEEGRVVKQDSQLSDALQELDAMKEELTLREEKIAQL 1524

Query: 1363 QEQSILNINE-----ENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIY 1417
            +      + E     +   ++++             +    E KV EL   L     E+ 
Sbjct: 1525 ESWLTTGMQEIEVLRQEKDVREAQMTELESRLAIVSKEISEEGKVAELESHLTNVVGEMD 1584

Query: 1418 QKTHEYTIT---LTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYE 1474
                E  +    + +   +  +V Q+L E  K  ++L  E+ S+L        +  +  E
Sbjct: 1585 SLREEKNLNKDKVAELESDLASVVQEL-EALKEEKNLKDEEISDLEARLTSESQEKSAEE 1643

Query: 1475 TMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIV 1534
                E E +   +++EL     E    ++Q+++L   L  +    ++ ++A E + +E+ 
Sbjct: 1644 DKVVELESDLASVVQELEALKEEKNLKDEQISDLEARLNSD----SQEKSAEEEKVVELE 1699

Query: 1535 T-LNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDE 1570
            + L   +  L+ +    + K+ K +   S     R E
Sbjct: 1700 SHLTGVLQELEALKEEKNQKVGKFLEMQSHLNDARQE 1736



 Score =  116 bits (278), Expect = 7e-24
 Identities = 260/1331 (19%), Positives = 572/1331 (42%), Gaps = 163/1331 (12%)

Query: 365  KGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDK 424
            K S ++ R++ R    +     + L  E L     +  NK E+ +L+  + S N +  + 
Sbjct: 579  KESDVLERQA-REAEMQAALDSANLEKEELKSHISESQNK-ELMELQAALDSANLEKAEL 636

Query: 425  EYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGT--------NTEDVN 476
            +  ++E                 L  ++   H    +   L+ +          N E ++
Sbjct: 637  KSRMAEIQEGQQTGMQDALNAANLEIEVLKNHVSESQNKELMELQAALDTANLANAELMS 696

Query: 477  EIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAAN-KNM-IKVKSNH- 533
             +A+++++ + E+   +   N+++   K   AE+Q  QL +  DA N  N+ I+V  NH 
Sbjct: 697  RMAEIEKEQQTEIQAALGSANLENAELKSLMAEQQNKQLMELQDALNTANLEIEVLKNHM 756

Query: 534  -KLKLKQMQKT--------IDN---FSKVSD-SNKEIVRLTEELHHLSQKVAELEEEKGN 580
             +++ +Q+ +T        ++N    S ++D  NK+++ L   L   + + A+++   G+
Sbjct: 757  TQVQNEQLMETQAVLDAANLENEELKSHLADVQNKQLMELQAALDLANAENADIKSRLGS 816

Query: 581  LQLHLV---------DYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELH 631
            ++   +          +    ++++ +     E E   E  +   S L ++     +ELH
Sbjct: 817  METDALTEAMTTLEKSHKELAVLQAALDSANQEREAFGEVHISENSQLRTELESASRELH 876

Query: 632  ILQQKYDE------------VEDKLADISQLQSDQVCSEIKSVHLEEQIDAL-SASKKEL 678
             L+++Y+E            +E + AD+++LQ+    S  +   LE + + + S+   ++
Sbjct: 877  SLKEQYEERDTTRLNEALATLEKQAADLTELQAALEISRGEKETLERRSEEMPSSDLNDI 936

Query: 679  ALVIENLKLDKE--QLYGTIKDLENDKEDIMNKLQ-----NYIQENMDLTDKLEKMSAE- 730
               +E+ +   +  ++   ++ L  +   + ++L+     +  Q  ++  +++  M AE 
Sbjct: 937  KATLESSQQSDQVREMQVVLETLTEENAALKDRLEELQTKDVNQVQVEEPEEILVMRAEL 996

Query: 731  KISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICR---LEESI-- 785
            ++S  L     EE+ ++QT+  +D  I +     +    ++ K K  +     L E++  
Sbjct: 997  EMSSALCDALQEEKDQLQTK--LDETIPDAAQATQTPHPDVDKLKGELMESLTLCEALNE 1054

Query: 786  ------AVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEK 839
                  + +E+ R  +E + D+    ++ K++  +E      +     A L    R  +K
Sbjct: 1055 EKNQLHSKLEETRKEIEMRTDESSDIIKMKEE-IAELRFVLLQKAEEYAELQQFTRWEDK 1113

Query: 840  QLLEIEHENK-ELQKKNQILLEENQNLQISLSDMQQHYNA-LVEKAN-RTDL-----AES 891
             L E E E + E+ +  +I+ +++++L+    D++    A L +  N +TDL     AE 
Sbjct: 1114 SLKEQESEYQCEINRLQEIMKQKDKDLR----DIETKITAQLTQSENEKTDLDFQLDAEK 1169

Query: 892  ESTKYQT-----QLRDLESNLKR-------ITHEHQTLIVQKKKEIEDLEIEFNTQIESA 939
            E  +  T     QL++    LK           E   L  +K++ + +LE+    ++   
Sbjct: 1170 ERNRSMTSELRQQLQEAYDRLKEKEGAEGASAEEGMELETEKRENVVELEV----RLAEV 1225

Query: 940  IRDKKVLNEKYEKNIEYVTQLEAQLQ---EYKNNIENLNMNVEELN----KMNLELIDKH 992
            +R+ + L EK  +  E VT+LE +L    + K N+E   ++  E       M +E + K 
Sbjct: 1226 LREMESLREKESQKEEMVTELETKLAGALQEKENVEEKKVHELESRLASILMEIEALKKE 1285

Query: 993  VQKQQTQSPDYTEQYINEINKLNALLKQ---KDEEIIALNQKINNAQVSYMSMVSDYESK 1049
               ++ +  D   +  N + +++ L ++   K+++++ L  ++N   +       + E K
Sbjct: 1286 KTVREEKVCDLEAKLANAVQEIDTLREEETLKEQKMVELESRLN---MVLQEQDGEKEEK 1342

Query: 1050 LAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILV---REQDDQIKE------------ 1094
            L + ++KL N+ +E + + ++    ++   EL+ L+    E+D  +KE            
Sbjct: 1343 LLELSSKLANLLQETEELREEKNFKEERIAELESLLGSAPEEDVDLKEERVMELESHLAN 1402

Query: 1095 -LKETKLTFEMNIPKTEGMI-ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQ 1152
             L+ET    +    K E +  + S +  + +D  +                +QE E   +
Sbjct: 1403 VLEETDSLRKAEAWKDERISELESRLGEVVNDKESGAEDKATELEAQLASVLQEVEALRE 1462

Query: 1153 ERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDN 1212
            E++V +EQ ++L + L       +Q +    E  G  V    Q++    +L+ +  E   
Sbjct: 1463 EKNVKEEQISELESRLAN-----VQQDKEGEE-EGRVVKQDSQLSDALQELDAMKEELTL 1516

Query: 1213 LLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLL 1272
                +A+L S +++     G +  E+ +Q    REA  Q TE E R+ + + E   E  +
Sbjct: 1517 REEKIAQLESWLTT-----GMQEIEVLRQEKDVREA--QMTELESRLAIVSKEISEEGKV 1569

Query: 1273 DSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSE--IEDE 1330
              ++S     TN +  M+ +   +N  +DK   +  L+   A V+ ++E L+ E  ++DE
Sbjct: 1570 AELESHL---TNVVGEMDSLREEKNLNKDK---VAELESDLASVVQELEALKEEKNLKDE 1623

Query: 1331 KVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXX 1390
            +++                 D   E +S      Q +  + EE   LK            
Sbjct: 1624 EISDLEARLTSESQEKSAEEDKVVELESDLASVVQELEALKEEK-NLKDEQISDLEARLN 1682

Query: 1391 XXXRVNDA-EAKVLELTHQLE--LKDSE-IYQKTHEYTITLTQRNDEFENVRQQLVEYEK 1446
               +   A E KV+EL   L   L++ E + ++ ++      +      + RQ+L E+  
Sbjct: 1683 SDSQEKSAEEEKVVELESHLTGVLQELEALKEEKNQKVGKFLEMQSHLNDARQEL-EFLN 1741

Query: 1447 RIEDLTYEKESELAILRLKMHENANHY-ETMQKESEIERVKLIEELNVKITESVSLNKQ- 1504
              ++L  E+ +EL      + +  + + E    E+E +   +++E+   + E  +L +Q 
Sbjct: 1742 EDKNLREEQMAELKSRFANVSQEQDIFREEKVAEAESKLANVLQEIEA-LKEGKNLREQH 1800

Query: 1505 VAELNKAL----EEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQ-KHVS 1559
            +AEL   L    +E+     E    LE++   ++   D +   + +  A +++++ +H  
Sbjct: 1801 MAELEAMLAHVSQEQDTVREEKVLELESRLSCVLQEMDTLKVEETLKEAKATELETRHSE 1860

Query: 1560 FASDTKQGRDE 1570
              +D ++ +DE
Sbjct: 1861 VLNDMERLQDE 1871



 Score =  107 bits (256), Expect = 3e-21
 Identities = 253/1294 (19%), Positives = 542/1294 (41%), Gaps = 128/1294 (9%)

Query: 143  DVTHLSNTIKEKDNALSVLQVKMKIM------ETTILDLQ---EKINEKDQIIEAKNKAT 193
            ++  L   +K+KD  L  ++ K+         E T LD Q   EK   +    E + +  
Sbjct: 1125 EINRLQEIMKQKDKDLRDIETKITAQLTQSENEKTDLDFQLDAEKERNRSMTSELRQQLQ 1184

Query: 194  TXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAME---AEWKDEKQRLLKDIESKDVRI 250
                              E  + + T+ +EN + +E   AE   E + L +    K+  +
Sbjct: 1185 EAYDRLKEKEGAEGASAEEGMELE-TEKRENVVELEVRLAEVLREMESLREKESQKEEMV 1243

Query: 251  SSLEE--ANKLLEAARFEISLEH---SKLAQELEQXXXXXXXXXXXXXXLA--KQSIEPS 303
            + LE   A  L E    E    H   S+LA  L +              +   +  +  +
Sbjct: 1244 TELETKLAGALQEKENVEEKKVHELESRLASILMEIEALKKEKTVREEKVCDLEAKLANA 1303

Query: 304  CEEKTEIEEKGSLEIANMTELTKKIEL-LEHLNCQIRQTNKELENKLATMGTESKAVSSP 362
             +E   + E+ +L+   M EL  ++ + L+  + +  +   EL +KLA +  E++ +   
Sbjct: 1304 VQEIDTLREEETLKEQKMVELESRLNMVLQEQDGEKEEKLLELSSKLANLLQETEELREE 1363

Query: 363  SK-KGSPLISRKSGRNTASK-----MKSPWSQLSSETLN--QDTDKKINKNEIAKLEMVI 414
               K   +   +S   +A +      +    +L S   N  ++TD  + K E  K E + 
Sbjct: 1364 KNFKEERIAELESLLGSAPEEDVDLKEERVMELESHLANVLEETDS-LRKAEAWKDERIS 1422

Query: 415  Q---SLNKDLVDKEYVISEKDTXXXXXXXXXXGK-DTLIAQLQLEHQQHMEGPSLIHVGT 470
            +    L + + DKE    +K T           + + L  +  ++ +Q  E  S +    
Sbjct: 1423 ELESRLGEVVNDKESGAEDKATELEAQLASVLQEVEALREEKNVKEEQISELESRLANVQ 1482

Query: 471  NTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVK 530
              ++  E  +V +Q  Q L+D +++++   + E+L   EE+I QL   +    + +  ++
Sbjct: 1483 QDKEGEEEGRVVKQDSQ-LSDALQELDA--MKEELTLREEKIAQLESWLTTGMQEIEVLR 1539

Query: 531  SNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDS 590
                ++  QM +     + VS    E  ++ E   HL+  V E++  +    L+    D 
Sbjct: 1540 QEKDVREAQMTELESRLAIVSKEISEEGKVAELESHLTNVVGEMDSLREEKNLNK---DK 1596

Query: 591  GRMIESDVYKKMIEMENLAETR-LK--AISLLESQKFDLVQELHILQQKYDEVEDKLADI 647
               +ESD+   + E+E L E + LK   IS LE++     QE    + K  E+E  LA +
Sbjct: 1597 VAELESDLASVVQELEALKEEKNLKDEEISDLEARLTSESQEKSAEEDKVVELESDLASV 1656

Query: 648  SQ-LQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDI 706
             Q L++ +    +K   + +    L++  +E +   E +   +  L G +++LE  KE+ 
Sbjct: 1657 VQELEALKEEKNLKDEQISDLEARLNSDSQEKSAEEEKVVELESHLTGVLQELEALKEEK 1716

Query: 707  MNKLQNYIQENMDLTD---KLEKMSAEKI--SELLAKINHEEQSKIQTQ-FGIDAKIQER 760
              K+  +++    L D   +LE ++ +K    E +A++     +  Q Q    + K+ E 
Sbjct: 1717 NQKVGKFLEMQSHLNDARQELEFLNEDKNLREEQMAELKSRFANVSQEQDIFREEKVAEA 1776

Query: 761  DLYIENIESELSKYKS-------RICRLEESIA-VMEDRRYSLERKADQLGS----YLQE 808
            +  + N+  E+   K         +  LE  +A V +++    E K  +L S     LQE
Sbjct: 1777 ESKLANVLQEIEALKEGKNLREQHMAELEAMLAHVSQEQDTVREEKVLELESRLSCVLQE 1836

Query: 809  KQKAYSEYTIQE---DELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNL 865
                  E T++E    EL  R + +++    ++ +L  I+ E   L+  N  ++ + Q  
Sbjct: 1837 MDTLKVEETLKEAKATELETRHSEVLNDMERLQDELTRIKDEKARLEAANYEIMSQMQKD 1896

Query: 866  QISL--------SDMQQHYN--ALVEKANRT------DLAE--SESTKYQTQLRDLESNL 907
             +++        ++++Q ++  A +EK  +       ++ E  ++S+    +L +L+  L
Sbjct: 1897 VVTMETQTEEDVAEVEQSHDLHAAIEKLRKVLTSKDQEICEVKAQSSHEMGRLEELQQCL 1956

Query: 908  K--------RITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQ 959
            +        RIT E + L  +K + +E   ++   ++  +I +  +L E+ E     + +
Sbjct: 1957 EEESREREERITAELRNLEAEKTR-LEAALVKAELELGDSISETCLLKEEMEMMESRLAE 2015

Query: 960  -LEAQLQEYKNNIENLNMNVEELNKM------NLELIDKHVQKQQTQSPDYTEQYINEIN 1012
              E+ L + +  +E L + ++    +       +E + + ++ +  ++     Q  +E  
Sbjct: 2016 GRESALGQQQQEMEELMVELDSARNLLSQKEDEIEKLQEFMKLENEEAIKQEAQSRHETK 2075

Query: 1013 KLNALLKQKDEEIIALNQKINN-AQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQL 1071
            +L+ LL+Q + E   + ++I    + S+  +  +  + + +   + + +E  +    ++ 
Sbjct: 2076 RLHNLLQQLEGESKLVKEQIRQECETSWQVVCEELRTAMQESEREKQRLEAALWNAEEKQ 2135

Query: 1072 LDSKQHNEE-LQILVREQDDQIKELKETKLTFEMNIPKTEGM--IISSTIEPMSDDANNV 1128
            + S Q +E  LQ +  E    ++E +  K   E+ + K E     +   ++   D+   V
Sbjct: 2136 VQSHQFSEHRLQGVCEELRTAMEESEREKERLEVALRKAEEKQESLEKEVKKRKDEVKRV 2195

Query: 1129 DXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTE---LQECYTKIIQLETLNTEL 1185
                           VQ+ EE  +  ++  E   KL+ E   L E   K+ Q E L  EL
Sbjct: 2196 RIESFK--------NVQDWEE--RANTICGEIQEKLDEEQAKLSETKEKLSQFEVLCEEL 2245

Query: 1186 TGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQ 1245
                    E+I+++K     +  + + L    A+++  ++  V     ++ E      A+
Sbjct: 2246 KEELKAKDEEIDRVKEDKRDIFNKKEMLEKQYAKMKKQVNQTVQSSIRDVGEA----EAR 2301

Query: 1246 READFQKTEHELRVQLSAFESKYEQL------LDSVQSSTQEETNKIVTMEQVT--SLQN 1297
              A  ++ E EL  + +  +   E++      +  +++  Q +  +    +  T  SL++
Sbjct: 2302 ANAVCEELEEELEAEKTKVKDAQEKVECQAKHICELEAKLQSQLTQSKGGDPTTRRSLES 2361

Query: 1298 KLQDKEEHLRNLQEKYADVINQIEILRSEIEDEK 1331
            +L  K+  +  L+ ++   I ++E    +++ EK
Sbjct: 2362 ELSAKKREMTVLEMEHTREILKLEERIRDLDSEK 2395



 Score = 94.3 bits (224), Expect = 2e-17
 Identities = 195/1009 (19%), Positives = 428/1009 (42%), Gaps = 99/1009 (9%)

Query: 619  LESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQI-DALSASKKE 677
            LES + ++     +L+ K  +V ++ A  +++Q+    + ++   L+  I ++ +    E
Sbjct: 562  LESAQEEIKTLKEMLEGKESDVLERQAREAEMQAALDSANLEKEELKSHISESQNKELME 621

Query: 678  LALVIENLKLDKEQLYGTIKDLENDKE----DIMNK-------LQNYIQEN-----MDLT 721
            L   +++  L+K +L   + +++  ++    D +N        L+N++ E+     M+L 
Sbjct: 622  LQAALDSANLEKAELKSRMAEIQEGQQTGMQDALNAANLEIEVLKNHVSESQNKELMELQ 681

Query: 722  DKLE--KMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRIC 779
              L+   ++  ++   +A+I  E+Q++IQ   G  A ++  +L  +++ +E  +   ++ 
Sbjct: 682  AALDTANLANAELMSRMAEIEKEQQTEIQAALG-SANLENAEL--KSLMAE--QQNKQLM 736

Query: 780  RLEESIAVMEDRRYSLERKADQL-GSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVE 838
             L++++         L+    Q+    L E Q       ++ +EL + LA       V  
Sbjct: 737  ELQDALNTANLEIEVLKNHMTQVQNEQLMETQAVLDAANLENEELKSHLA------DVQN 790

Query: 839  KQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQT 898
            KQL+E       LQ    +   EN +++  L  M+   +AL E     + +  E    Q 
Sbjct: 791  KQLME-------LQAALDLANAENADIKSRLGSMET--DALTEAMTTLEKSHKELAVLQA 841

Query: 899  QLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIES-AIRDKKVLNEKY---EKNI 954
             L       +     H +   Q + E+E    E ++  E    RD   LNE     EK  
Sbjct: 842  ALDSANQEREAFGEVHISENSQLRTELESASRELHSLKEQYEERDTTRLNEALATLEKQA 901

Query: 955  EYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKL 1014
              +T+L+A L+  +   E L    EE+   +L  I   ++  Q QS        +++ ++
Sbjct: 902  ADLTELQAALEISRGEKETLERRSEEMPSSDLNDIKATLESSQ-QS--------DQVREM 952

Query: 1015 NALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDS 1074
              +L+   EE  AL  ++   Q   ++ V   E +      ++  M  E++ +S  L D+
Sbjct: 953  QVVLETLTEENAALKDRLEELQTKDVNQVQVEEPE------EILVMRAELE-MSSALCDA 1005

Query: 1075 KQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTI--EPMSDDANNVDXXX 1132
             Q  EE   L  + D+ I +  +   T   ++ K +G ++ S    E ++++ N +    
Sbjct: 1006 LQ--EEKDQLQTKLDETIPDAAQATQTPHPDVDKLKGELMESLTLCEALNEEKNQLHSKL 1063

Query: 1133 XXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVN 1192
                     ++  E  + I+    ++E+ A+L   L +   +  +L+   T      +  
Sbjct: 1064 EETRKEIE-MRTDESSDIIK----MKEEIAELRFVLLQKAEEYAELQQF-TRWEDKSLKE 1117

Query: 1193 QEQINQLK-SKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQ 1251
            QE   Q + ++L+++  + D  L    ++ + I++ + Q   E  +L  Q  A++E +  
Sbjct: 1118 QESEYQCEINRLQEIMKQKDKDLR---DIETKITAQLTQSENEKTDLDFQLDAEKERNRS 1174

Query: 1252 KTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVT--MEQVTSLQNKLQDKEEHLRNL 1309
             T  ELR QL     + ++  +  + ++ EE  ++ T   E V  L+ +L +    + +L
Sbjct: 1175 MTS-ELRQQLQEAYDRLKEK-EGAEGASAEEGMELETEKRENVVELEVRLAEVLREMESL 1232

Query: 1310 QEKYA---DVINQIEI-LRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQ 1365
            +EK +   +++ ++E  L   +++++                   ++    +  K ++E+
Sbjct: 1233 REKESQKEEMVTELETKLAGALQEKENVEEKKVHELESRLASILMEIEALKKE-KTVREE 1291

Query: 1366 SILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTI 1425
             + ++  + A   +              ++ + E++   L   L+ +D E  +K  E + 
Sbjct: 1292 KVCDLEAKLANAVQEIDTLREEETLKEQKMVELESR---LNMVLQEQDGEKEEKLLELSS 1348

Query: 1426 TLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERV 1485
             L     E E +R++    E+RI +L        ++L     E+ +  E    E E    
Sbjct: 1349 KLANLLQETEELREEKNFKEERIAELE-------SLLGSAPEEDVDLKEERVMELESHLA 1401

Query: 1486 KLIEELNVKITESVSLNKQVAELNKALEEEV----AKTNEMQTALENQEIEIVTLNDEIT 1541
             ++EE +         +++++EL   L E V    +   +  T LE Q   ++   + + 
Sbjct: 1402 NVLEETDSLRKAEAWKDERISELESRLGEVVNDKESGAEDKATELEAQLASVLQEVEALR 1461

Query: 1542 NLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELD 1590
              +N+     S+++  ++     K+G +E      + +L DA+   ELD
Sbjct: 1462 EEKNVKEEQISELESRLANVQQDKEGEEEGRVVKQDSQLSDAL--QELD 1508



 Score = 43.2 bits (97), Expect = 0.061
 Identities = 98/570 (17%), Positives = 254/570 (44%), Gaps = 50/570 (8%)

Query: 218  MTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQE 277
            M++MQ++ + ME + +++    + ++E      +++E+  K+L +   EI    ++ + E
Sbjct: 1890 MSQMQKDVVTMETQTEED----VAEVEQSHDLHAAIEKLRKVLTSKDQEICEVKAQSSHE 1945

Query: 278  LEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIE-EKGSLEIANMTELTKKIELLEHLN- 335
            + +               +++  E    E   +E EK  LE A +     ++EL + ++ 
Sbjct: 1946 MGRLEELQQCLEEE----SREREERITAELRNLEAEKTRLEAALVKA---ELELGDSISE 1998

Query: 336  -CQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETL 394
             C +++  + +E++LA  G ES       +    ++   S RN  S+ +    +L  E +
Sbjct: 1999 TCLLKEEMEMMESRLAE-GRESALGQQQQEMEELMVELDSARNLLSQKEDEIEKLQ-EFM 2056

Query: 395  NQDTDKKINKNEIAKLEMV-IQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQ 453
              + ++ I +   ++ E   + +L + L  +  ++ E+             ++   A  +
Sbjct: 2057 KLENEEAIKQEAQSRHETKRLHNLLQQLEGESKLVKEQIRQECETSWQVVCEELRTAMQE 2116

Query: 454  LEHQQHMEGPSLIH-----VGTNTEDVNEIAKVQEQLKQELND-----EIKDVNVKDLIE 503
             E ++     +L +     V ++    + +  V E+L+  + +     E  +V ++   E
Sbjct: 2117 SEREKQRLEAALWNAEEKQVQSHQFSEHRLQGVCEELRTAMEESEREKERLEVALRKAEE 2176

Query: 504  KLKSAEEQITQLNDEIDAAN----KNMIKVKSNHKLKLKQMQKTIDNF-SKVSDSNKEIV 558
            K +S E+++ +  DE+        KN+   +        ++Q+ +D   +K+S++ +++ 
Sbjct: 2177 KQESLEKEVKKRKDEVKRVRIESFKNVQDWEERANTICGEIQEKLDEEQAKLSETKEKLS 2236

Query: 559  R-------LTEELHHLSQKVAELEEEKGNL--QLHLVDYDSGRMIESDVYKKMIEMENLA 609
            +       L EEL    +++  ++E+K ++  +  +++    +M +         + ++ 
Sbjct: 2237 QFEVLCEELKEELKAKDEEIDRVKEDKRDIFNKKEMLEKQYAKMKKQVNQTVQSSIRDVG 2296

Query: 610  ETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADI----SQLQSDQVCSEIKSVHLE 665
            E   +A ++ E  + +L  E   ++   ++VE +   I    ++LQS    S+       
Sbjct: 2297 EAEARANAVCEELEEELEAEKTKVKDAQEKVECQAKHICELEAKLQSQLTQSKGGDPTTR 2356

Query: 666  EQIDA-LSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNY----IQENMDL 720
              +++ LSA K+E+ ++      +  +L   I+DL+++K+ +  K + Y     +E+   
Sbjct: 2357 RSLESELSAKKREMTVLEMEHTREILKLEERIRDLDSEKKFLDEKNREYRNELRREHQRA 2416

Query: 721  TDKLEKMSAEKISELLAKINHEEQSKIQTQ 750
             D  + +S + +  +L   + +  SK++ +
Sbjct: 2417 ADSSDTVSQKHLFVVLYVFHRDRNSKLKQE 2446



 Score = 37.5 bits (83), Expect = 3.0
 Identities = 52/235 (22%), Positives = 102/235 (43%), Gaps = 15/235 (6%)

Query: 1363 QEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAK-VLELTHQLELKDSEIYQ-KT 1420
            +E  +L      A+++ +              +++++ K ++EL   L+  + E  + K+
Sbjct: 579  KESDVLERQAREAEMQAALDSANLEKEELKSHISESQNKELMELQAALDSANLEKAELKS 638

Query: 1421 HEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHE-NANHYETMQKE 1479
                I   Q+    + +    +E E     ++  +  EL  L+  +   N  + E M + 
Sbjct: 639  RMAEIQEGQQTGMQDALNAANLEIEVLKNHVSESQNKELMELQAALDTANLANAELMSRM 698

Query: 1480 SEIERVKLIEELNVKITESV-SLNKQVAELNKALEEEVAKT-NEMQTALENQEIEIVTLN 1537
            +EIE+     E   +I  ++ S N + AEL   + E+  K   E+Q AL    +EI  L 
Sbjct: 699  AEIEK-----EQQTEIQAALGSANLENAELKSLMAEQQNKQLMELQDALNTANLEIEVLK 753

Query: 1538 DEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDLA 1592
            + +T +QN       + Q  +  A+   +     L +  NK+L++   +A LDLA
Sbjct: 754  NHMTQVQN---EQLMETQAVLDAANLENEELKSHLADVQNKQLMEL--QAALDLA 803


>UniRef50_A2DUI3 Cluster: Viral A-type inclusion protein, putative;
            n=1; Trichomonas vaginalis G3|Rep: Viral A-type inclusion
            protein, putative - Trichomonas vaginalis G3
          Length = 1262

 Score =  132 bits (319), Expect = 8e-29
 Identities = 210/1104 (19%), Positives = 472/1104 (42%), Gaps = 108/1104 (9%)

Query: 484  QLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKT 543
            Q  +  ++  K++  KD   K  +A +  + +         +   + SN K   K  +K 
Sbjct: 109  QSSKSSSNVTKNIKFKDFSAKQTTASKLASDMKQSYSEFVSSSQNLFSNLK---KLTKKV 165

Query: 544  IDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMI 603
            +   S +  S+K  +   +      QK+ E E  +  L+  L+  +S    + + Y+   
Sbjct: 166  VAKQSSIIQSDKRFISEAKS----QQKIDEAEINR--LKQQLISTES----QLNHYRTQ- 214

Query: 604  EMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVH 663
                L+  R K     +     +++E   L+++  ++  KL + S + +D+  +E++   
Sbjct: 215  ----LSNIRAKPADKTDYSYNSIIEENERLKKENRDLSQKLRNSSSIVTDKNETELEKEA 270

Query: 664  LEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDK 723
             ++Q++       E+      L    ++L   +K+     ++ +N LQN I E  +L +K
Sbjct: 271  KDKQLELALEHIDEIDNERRRLININKKLLNKVKEYSQSNDESLN-LQNIISEKSELNEK 329

Query: 724  LE------KMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSR 777
            ++      +   EK++  +  + HE +   +       K ++ +    +++ EL+   S 
Sbjct: 330  MDAEMKILRNDKEKLNIEIETLKHENEELKKNNKKQIVKYKQLETDYRDLKIELNPIISE 389

Query: 778  ICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVV 837
              +++E +    +R+ S+E  +D   + + E++    E   +  E +  L + +  ++  
Sbjct: 390  NEKMKEEVD--NERQKSMESMSDT--AKVTEREAHLMEEISKHKEKIQNLEISLSKEKKF 445

Query: 838  EKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQ 897
             K L + E E  +++++ + L+EEN+N++  L+   +   +L +K +  +  +S     +
Sbjct: 446  SKSLSKSEEELTQVKRQMEDLMEENENIKEILA---KSVESLKKKKSEINDLKSLVENQK 502

Query: 898  TQLRDLESNLKRITHEHQTLIVQKKKEIEDL--EIEFNTQIESAIRD---KKVLNEKYEK 952
            T++ D+E + + + +E    I Q+KKEIE L  EIE N    +  RD   K +   + EK
Sbjct: 503  TEISDVEKSKEELYNE----IEQQKKEIEQLKKEIERNDMNFNNYRDMSNKTLRKTEEEK 558

Query: 953  N------IEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELID--KHVQKQQ----TQS 1000
            N      ++Y      + + YK     L    +E++ +  ++ D  K + K Q    ++S
Sbjct: 559  NEIERQFVKYKLDTNTESETYKTLQTTLTDRNDEISNLRKKVSDFQKEIIKMQEEMHSKS 618

Query: 1001 PDYTE---QYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKL 1057
             D+ +   ++ N+I  L  L +    ++I+       ++    + +  YE+ +   + ++
Sbjct: 619  KDFDKNKAEFTNKIKNLEKLNEDLRSQVISSQNTRKKSEDMMEASMKQYENDILNLSQQI 678

Query: 1058 ENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISST 1117
            E+     Q + KQ    ++   +++ +  E +D+I + KE KL  ++   + +   I S 
Sbjct: 679  ESNNSNHQEIIKQC--KEESGNKIKEIEAEYEDKINKQKE-KLENKIKDIEFQYSEIKSK 735

Query: 1118 IEPMSDDANNVDXXXXXXXXXXXXL--KVQEEEEFIQERSVLQEQSAKLNTELQECYTKI 1175
             E +++                  L   ++   EF    + ++E++ KLN          
Sbjct: 736  YEEVNNQIQEASQMKETFDNCCISLFGSIKTSNEFSSLINQMKEENLKLN---------- 785

Query: 1176 IQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEI 1235
             +L   N  LTG       ++ ++    + L +EN NL + +  + S  S  +      +
Sbjct: 786  -ELSKTNEILTG-------KLGKIYMANKILKSENANLKNNLV-ISSQSSRKISDEFKNL 836

Query: 1236 AELWKQ--HLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQV- 1292
            ++ + +  + ++   +  KT +E   +L+   +        + S  +  TN    +E+  
Sbjct: 837  SKKYNELNNSSENLTNDNKTLNEKNQKLNELNNNLSSEFLKLSSQNEVLTNNQKILEEKH 896

Query: 1293 TSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDL 1352
              LQN  +  EE+ + L  ++ ++    E L    E  K  +                D+
Sbjct: 897  NKLQNDHKQLEENFQKLNNEHQELTTNYEKLTENHEKLKKEYETATSELSISMN----DV 952

Query: 1353 RTENQSYKQMQEQSILNINEE-------NAQLKKSSXXXXXXXXXXXXRVNDAEAKVLEL 1405
                + YKQ++++ I NIN +       N +LK                ++  + +  E+
Sbjct: 953  NELTEHYKQLKDE-IFNINNQYNEIISDNERLKTELELTKDELNESNNNLSKIKLENEEM 1011

Query: 1406 THQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLK 1465
            +  L + +S+  +  +E    L + N E EN+   L   +K I     E +  L  L  K
Sbjct: 1012 SKSLNISESDKKKLENE----LEENNREIENISLSL---DKEISK-NDELQKCLTKLSSK 1063

Query: 1466 MHENANHYETM-QKESEIERV-KLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEM- 1522
            + ++++  + + ++  E++   K I + N K+   ++ N Q+ ++NK   E    + E+ 
Sbjct: 1064 ITDSSSRIDDLSERNKEMKEYNKQILQENKKLKRKLNSNSQIPDINKLQSENKTLSQELF 1123

Query: 1523 QTALENQEI--EIVTLNDEITNLQ 1544
            +   ENQE+   + T+   ++ L+
Sbjct: 1124 KLKDENQELLERVATMTLSLSQLE 1147



 Score =  116 bits (278), Expect = 7e-24
 Identities = 186/986 (18%), Positives = 422/986 (42%), Gaps = 72/986 (7%)

Query: 148  SNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXX 207
            S+ + +K+      + K K +E  +  + E  NE+ ++I    K                
Sbjct: 255  SSIVTDKNETELEKEAKDKQLELALEHIDEIDNERRRLININKKLLNKVKEYSQSNDESL 314

Query: 208  XXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEI 267
                ++   + +++ E   A     +++K++L  +IE+       L++ NK       ++
Sbjct: 315  NL--QNIISEKSELNEKMDAEMKILRNDKEKLNIEIETLKHENEELKKNNKKQIVKYKQL 372

Query: 268  SLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKK 327
              ++  L  EL                  ++S+E S  +  ++ E+ +  +  +++  +K
Sbjct: 373  ETDYRDLKIELNPIISENEKMKEEVDNERQKSME-SMSDTAKVTEREAHLMEEISKHKEK 431

Query: 328  IELLEHLNCQIRQTNKEL---ENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKS 384
            I+ LE    + ++ +K L   E +L  +  + + +   ++    ++++     +  K KS
Sbjct: 432  IQNLEISLSKEKKFSKSLSKSEEELTQVKRQMEDLMEENENIKEILAKSV--ESLKKKKS 489

Query: 385  PWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXG 444
              + L S   NQ T+    +    +L   I+   K++   +  I   D            
Sbjct: 490  EINDLKSLVENQKTEISDVEKSKEELYNEIEQQKKEIEQLKKEIERNDMNFNNYRDMS-- 547

Query: 445  KDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEK 504
             +  + + + E  +         + TNTE  +E  K  +    + NDEI ++      +K
Sbjct: 548  -NKTLRKTEEEKNEIERQFVKYKLDTNTE--SETYKTLQTTLTDRNDEISNLR-----KK 599

Query: 505  LKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEEL 564
            +   +++I ++ +E+ + +K+  K K+    K+K ++K  ++      S++   + +E++
Sbjct: 600  VSDFQKEIIKMQEEMHSKSKDFDKNKAEFTNKIKNLEKLNEDLRSQVISSQNTRKKSEDM 659

Query: 565  HHLSQKVAELEEEKGNLQLHLVDYDSG-----RMIESDVYKKMIEMENLAETRL-KAISL 618
               S K  + E +  NL   +   +S      +  + +   K+ E+E   E ++ K    
Sbjct: 660  MEASMK--QYENDILNLSQQIESNNSNHQEIIKQCKEESGNKIKEIEAEYEDKINKQKEK 717

Query: 619  LESQKFDLVQELHILQQKYDEVEDKLADISQLQS--DQVC-SEIKSVHLEEQIDALSASK 675
            LE++  D+  +   ++ KY+EV +++ + SQ++   D  C S   S+    +  +L    
Sbjct: 718  LENKIKDIEFQYSEIKSKYEEVNNQIQEASQMKETFDNCCISLFGSIKTSNEFSSLINQM 777

Query: 676  KELALVIENLKLDKEQLYGTI-------KDLENDKEDIMNKLQNYIQENMDLTDKLEKMS 728
            KE  L +  L    E L G +       K L+++  ++ N L    Q +  ++D+ + +S
Sbjct: 778  KEENLKLNELSKTNEILTGKLGKIYMANKILKSENANLKNNLVISSQSSRKISDEFKNLS 837

Query: 729  AEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVM 788
             +K +EL    N+  ++       ++ K Q+ +    N+ SE  K  S+   L  +  ++
Sbjct: 838  -KKYNEL----NNSSENLTNDNKTLNEKNQKLNELNNNLSSEFLKLSSQNEVLTNNQKIL 892

Query: 789  EDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHEN 848
            E++   L+    QL    Q+    + E T   ++L        +H+++ ++        +
Sbjct: 893  EEKHNKLQNDHKQLEENFQKLNNEHQELTTNYEKLTE------NHEKLKKEYETATSELS 946

Query: 849  KELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLK 908
              +   N+ L E  + L+  + ++   YN ++    R    E E TK   +L +  +NL 
Sbjct: 947  ISMNDVNE-LTEHYKQLKDEIFNINNQYNEIISDNERLK-TELELTK--DELNESNNNLS 1002

Query: 909  RITHEHQ------TLIVQKKKEIEDLEIEFNTQIE--SAIRDKKVLNEKYEKNIEYVTQL 960
            +I  E++       +    KK++E+   E N +IE  S   DK++   K ++  + +T+L
Sbjct: 1003 KIKLENEEMSKSLNISESDKKKLENELEENNREIENISLSLDKEI--SKNDELQKCLTKL 1060

Query: 961  EAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQ 1020
             +++ +  + I++L+   +E+ + N +++ ++ + ++  +   +   I +INKL +  K 
Sbjct: 1061 SSKITDSSSRIDDLSERNKEMKEYNKQILQENKKLKRKLN---SNSQIPDINKLQSENKT 1117

Query: 1021 KDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEE 1080
              +E+     K+ +     +  V+     L+Q   + E  EEE   +S Q      H EE
Sbjct: 1118 LSQELF----KLKDENQELLERVATMTLSLSQL--EFEE-EEETMLLSPQFDQLNNHTEE 1170

Query: 1081 -LQILVREQDDQIKELKETKLTFEMN 1105
             ++ ++       K  +   LT  +N
Sbjct: 1171 KIKSVISSPRSSKKRNRPVFLTQSLN 1196



 Score =  105 bits (251), Expect = 1e-20
 Identities = 169/897 (18%), Positives = 390/897 (43%), Gaps = 69/897 (7%)

Query: 705  DIMNKLQNYIQENMDL-----TDKLEKM--SAEKISELLAKINHEEQSKIQT---QFGID 754
            ++ N+L  YI++ M       T+   KM  S++  S +   I  ++ S  QT   +   D
Sbjct: 80   NVPNELNQYIRDLMKTKKSFPTNSTNKMIQSSKSSSNVTKNIKFKDFSAKQTTASKLASD 139

Query: 755  AKIQERDLYI--ENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKA 812
             K    +     +N+ S L K   ++   + SI +  D+R+  E K+ Q     + +   
Sbjct: 140  MKQSYSEFVSSSQNLFSNLKKLTKKVVAKQSSI-IQSDKRFISEAKSQQ--KIDEAEINR 196

Query: 813  YSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDM 872
              +  I  +  +N     + + R   K   + ++    + ++N+ L +EN++L   L   
Sbjct: 197  LKQQLISTESQLNHYRTQLSNIRA--KPADKTDYSYNSIIEENERLKKENRDLSQKL--- 251

Query: 873  QQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEF 932
             ++ +++V   N T+L E E+   Q +L  LE ++  I +E + LI   KK +  ++ E+
Sbjct: 252  -RNSSSIVTDKNETEL-EKEAKDKQLELA-LE-HIDEIDNERRRLININKKLLNKVK-EY 306

Query: 933  NTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKH 992
            +   + ++  + +++EK E N     +++A+++  +N+ E LN+ +E L   N EL  K+
Sbjct: 307  SQSNDESLNLQNIISEKSELN----EKMDAEMKILRNDKEKLNIEIETLKHENEEL-KKN 361

Query: 993  VQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSD---YESK 1049
             +KQ  +       Y +   +LN ++ + ++    + ++++N +   M  +SD      +
Sbjct: 362  NKKQIVKYKQLETDYRDLKIELNPIISENEK----MKEEVDNERQKSMESMSDTAKVTER 417

Query: 1050 LAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKT 1109
             A    ++   +E++Q +   L   K+ ++ L     E+  Q+K   E  +    NI + 
Sbjct: 418  EAHLMEEISKHKEKIQNLEISLSKEKKFSKSLS-KSEEELTQVKRQMEDLMEENENIKEI 476

Query: 1110 EGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQ 1169
                + S ++    + N++             ++ + +EE   E    +++  +L  E++
Sbjct: 477  LAKSVES-LKKKKSEINDLKSLVENQKTEISDVE-KSKEELYNEIEQQKKEIEQLKKEIE 534

Query: 1170 ECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVD 1229
                       ++ +        +E+ N+++ +  +   + +    T +E   ++ + + 
Sbjct: 535  RNDMNFNNYRDMSNKTLRK---TEEEKNEIERQFVKYKLDTN----TESETYKTLQTTLT 587

Query: 1230 QRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTM 1289
             R  EI+ L K+ ++  + +  K + E+  +   F+    +  + +++   E+ N+ +  
Sbjct: 588  DRNDEISNLRKK-VSDFQKEIIKMQEEMHSKSKDFDKNKAEFTNKIKNL--EKLNEDLR- 643

Query: 1290 EQVTSLQNKLQDKEEHLRNLQEKYA-DVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXX 1348
             QV S QN  +  E+ +    ++Y  D++N  + + S   + +                 
Sbjct: 644  SQVISSQNTRKKSEDMMEASMKQYENDILNLSQQIESNNSNHQEIIKQCKEESGNKIKEI 703

Query: 1349 XXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQ 1408
              +   +    K+  E  I +I  + +++K               ++ +A +++ E    
Sbjct: 704  EAEYEDKINKQKEKLENKIKDIEFQYSEIKSK-------YEEVNNQIQEA-SQMKETFDN 755

Query: 1409 LELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHE 1468
              +      + ++E++  + Q  +E  N++  L E  K  E LT +        ++   E
Sbjct: 756  CCISLFGSIKTSNEFSSLINQMKEE--NLK--LNELSKTNEILTGKLGKIYMANKILKSE 811

Query: 1469 NANHYETMQKESEIERVKLIEE---LNVKITESVSLNKQVAELNKALEEEVAKTNEMQTA 1525
            NAN    +   S+  R K+ +E   L+ K  E  + ++ +   NK L E+  K NE+   
Sbjct: 812  NANLKNNLVISSQSSR-KISDEFKNLSKKYNELNNSSENLTNDNKTLNEKNQKLNELNNN 870

Query: 1526 LENQEIEIVTLNDEITNLQNMVRASSSKIQK-HVSFASDTKQGRDEQLDNTMNKELL 1581
            L ++ +++ + N+ +TN Q ++    +K+Q  H     + ++  +E  + T N E L
Sbjct: 871  LSSEFLKLSSQNEVLTNNQKILEEKHNKLQNDHKQLEENFQKLNNEHQELTTNYEKL 927



 Score =  104 bits (250), Expect = 2e-20
 Identities = 181/977 (18%), Positives = 414/977 (42%), Gaps = 65/977 (6%)

Query: 355  ESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQ-DTDKK----INKNEIAK 409
            E++ +S   +  S +++ K+      + K    +L+ E +++ D +++    INK  + K
Sbjct: 243  ENRDLSQKLRNSSSIVTDKNETELEKEAKDKQLELALEHIDEIDNERRRLININKKLLNK 302

Query: 410  LEMVIQSLNKDLVDKEYVISEKD--TXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIH 467
            ++   QS N + ++ + +ISEK                D     +++E  +H       +
Sbjct: 303  VKEYSQS-NDESLNLQNIISEKSELNEKMDAEMKILRNDKEKLNIEIETLKHENEELKKN 361

Query: 468  VGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLND--EIDAANKN 525
                     ++      LK ELN  I + N K   E     ++ +  ++D  ++     +
Sbjct: 362  NKKQIVKYKQLETDYRDLKIELNPIISE-NEKMKEEVDNERQKSMESMSDTAKVTEREAH 420

Query: 526  MIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHL 585
            +++  S HK K++ ++ ++    K S   K + +  EEL  + +++ +L EE  N++  L
Sbjct: 421  LMEEISKHKEKIQNLEISLSKEKKFS---KSLSKSEEELTQVKRQMEDLMEENENIKEIL 477

Query: 586  VDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLA 645
                  + +ES + KK  E+ +L        SL+E+QK ++       ++ Y+E+E +  
Sbjct: 478  A-----KSVES-LKKKKSEINDLK-------SLVENQKTEISDVEKSKEELYNEIEQQKK 524

Query: 646  DISQLQSDQVCSEIKSVHLEEQ----IDALSASKKELALVIENLKLDKEQLYGTIKDLEN 701
            +I QL+ +   +++   +  +     +      K E+       KLD      T K L+ 
Sbjct: 525  EIEQLKKEIERNDMNFNNYRDMSNKTLRKTEEEKNEIERQFVKYKLDTNTESETYKTLQT 584

Query: 702  DKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERD 761
               D  +++ N  ++  D   ++ KM  E  S+  +K   + +++   +     K+ E D
Sbjct: 585  TLTDRNDEISNLRKKVSDFQKEIIKMQEEMHSK--SKDFDKNKAEFTNKIKNLEKLNE-D 641

Query: 762  LYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQE--KQ-KAYSEYTI 818
            L  + I S+ ++ KS    +E S+   E+   +L ++ +   S  QE  KQ K  S   I
Sbjct: 642  LRSQVISSQNTRKKSEDM-MEASMKQYENDILNLSQQIESNNSNHQEIIKQCKEESGNKI 700

Query: 819  QEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNA 878
            +E E      +    +++ E ++ +IE +  E++ K +   E N  +Q   S M++ ++ 
Sbjct: 701  KEIEAEYEDKINKQKEKL-ENKIKDIEFQYSEIKSKYE---EVNNQIQ-EASQMKETFDN 755

Query: 879  LVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTL------IVQKKKEIEDLEIEF 932
                   +    +E +    Q+++    L  ++  ++ L      I    K ++      
Sbjct: 756  CCISLFGSIKTSNEFSSLINQMKEENLKLNELSKTNEILTGKLGKIYMANKILKSENANL 815

Query: 933  NTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKH 992
               +  + +  + ++++++   +   +L    +   N+ + LN   ++LN++N  L  + 
Sbjct: 816  KNNLVISSQSSRKISDEFKNLSKKYNELNNSSENLTNDNKTLNEKNQKLNELNNNLSSEF 875

Query: 993  VQ-KQQTQSPDYTEQYINEI-NKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKL 1050
            ++   Q +     ++ + E  NKL    KQ +E    LN +      +Y  +  ++E   
Sbjct: 876  LKLSSQNEVLTNNQKILEEKHNKLQNDHKQLEENFQKLNNEHQELTTNYEKLTENHEKLK 935

Query: 1051 AQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTE 1110
             ++ T    +   M  V++     KQ  +E+  +  + ++ I +    +L  E+ + K E
Sbjct: 936  KEYETATSELSISMNDVNELTEHYKQLKDEIFNINNQYNEIISD--NERLKTELELTKDE 993

Query: 1111 GMIISSTIEPMSDDANNVDXXXXXXXXXXXXLK--VQEEEEFIQERSVLQEQSAKLNTEL 1168
                ++ +  +  +   +             L+  ++E    I+  S+  ++    N EL
Sbjct: 994  LNESNNNLSKIKLENEEMSKSLNISESDKKKLENELEENNREIENISLSLDKEISKNDEL 1053

Query: 1169 QECYTKI-IQLETLNTELTGHDVVNQE------QINQLKSKLEQLNTENDNLLSTVAELR 1221
            Q+C TK+  ++   ++ +      N+E      QI Q   KL++    N   +  + +L+
Sbjct: 1054 QKCLTKLSSKITDSSSRIDDLSERNKEMKEYNKQILQENKKLKRKLNSNSQ-IPDINKLQ 1112

Query: 1222 SSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQE 1281
            S  +  + Q  F++ +   Q L +R A    +  +L  +            D + + T+E
Sbjct: 1113 SE-NKTLSQELFKLKD-ENQELLERVATMTLSLSQLEFEEEEETMLLSPQFDQLNNHTEE 1170

Query: 1282 ETNKIVTMEQVTSLQNK 1298
            +   +++  + +  +N+
Sbjct: 1171 KIKSVISSPRSSKKRNR 1187



 Score = 84.2 bits (199), Expect = 3e-14
 Identities = 187/949 (19%), Positives = 389/949 (40%), Gaps = 73/949 (7%)

Query: 94   LANTLKQKEILMEKIK-QYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIK 152
            L N  ++  I +E +K + +EL K +   IV+               +L  +  +S   K
Sbjct: 337  LRNDKEKLNIEIETLKHENEELKKNNKKQIVKYKQLETDYRDLKI--ELNPI--ISENEK 392

Query: 153  EKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXE 212
             K+   +  Q  M+ M  T    + + +  ++I  +K+K                     
Sbjct: 393  MKEEVDNERQKSMESMSDTAKVTEREAHLMEEI--SKHKEKIQNLEISLSKEKKFSKSLS 450

Query: 213  DTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEIS-LEH 271
             +++++T+++     +  E ++ K+ L K +ES   + S + +   L+E  + EIS +E 
Sbjct: 451  KSEEELTQVKRQMEDLMEENENIKEILAKSVESLKKKKSEINDLKSLVENQKTEISDVEK 510

Query: 272  SK--LAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIE 329
            SK  L  E+EQ                K+ IE     + ++      +++N T L K  E
Sbjct: 511  SKEELYNEIEQQKKEIEQL--------KKEIE-----RNDMNFNNYRDMSNKT-LRKTEE 556

Query: 330  LLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQL 389
                +  Q  +   +   +  T  T    ++  + + S L  RK   +   ++     ++
Sbjct: 557  EKNEIERQFVKYKLDTNTESETYKTLQTTLTDRNDEISNL--RKKVSDFQKEIIKMQEEM 614

Query: 390  SSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISE-KDTXXXXXXXXXXGKDTL 448
             S++ + D +K    N+I  LE + + L   ++  +    + +D               L
Sbjct: 615  HSKSKDFDKNKAEFTNKIKNLEKLNEDLRSQVISSQNTRKKSEDMMEASMKQYENDILNL 674

Query: 449  IAQLQLEHQQHME---------GPSLIHVGTNTEDVNEIAKVQEQLKQELND-EIKDVNV 498
              Q++  +  H E         G  +  +    ED  +I K +E+L+ ++ D E +   +
Sbjct: 675  SQQIESNNSNHQEIIKQCKEESGNKIKEIEAEYED--KINKQKEKLENKIKDIEFQYSEI 732

Query: 499  KDLIEKLKSAEEQITQLNDEIDAANKNM---IKVKSNHKLKLKQMQKTIDNFSKVSDSNK 555
            K   E++ +  ++ +Q+ +  D    ++   IK  +     + QM++     +++S +N 
Sbjct: 733  KSKYEEVNNQIQEASQMKETFDNCCISLFGSIKTSNEFSSLINQMKEENLKLNELSKTN- 791

Query: 556  EIVRLTEELHHLSQKVAELEEEKGNLQLHLV-DYDSGRMIESDVYKKMIEMENLAETRLK 614
            EI  LT +L  +      L+ E  NL+ +LV    S R I SD +K + +  N  E    
Sbjct: 792  EI--LTGKLGKIYMANKILKSENANLKNNLVISSQSSRKI-SDEFKNLSKKYN--ELNNS 846

Query: 615  AISLLESQKFDLVQELHILQQKYDEVEDKLA-DISQLQSDQVCSEIKSVHLEEQIDALSA 673
            + +L    K      L+   QK +E+ + L+ +  +L S           LEE+ + L  
Sbjct: 847  SENLTNDNK-----TLNEKNQKLNELNNNLSSEFLKLSSQNEVLTNNQKILEEKHNKLQN 901

Query: 674  SKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQE-NMDLTDKLEKMSAEK- 731
              K+L    + L  + ++L    + L  + E +  + +    E ++ + D  E     K 
Sbjct: 902  DHKQLEENFQKLNNEHQELTTNYEKLTENHEKLKKEYETATSELSISMNDVNELTEHYKQ 961

Query: 732  ISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDR 791
            + + +  IN++    I     +  +++     +    + LSK K     + +S+ + E  
Sbjct: 962  LKDEIFNINNQYNEIISDNERLKTELELTKDELNESNNNLSKIKLENEEMSKSLNISESD 1021

Query: 792  RYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKEL 851
            +  LE + ++    ++    +  +   + DEL   L  L         ++ ++   NKE+
Sbjct: 1022 KKKLENELEENNREIENISLSLDKEISKNDELQKCLTKLSSKITDSSSRIDDLSERNKEM 1081

Query: 852  QKKNQILLEENQNLQISLSDMQQ--HYNALVEKANRTDLAESESTKYQTQLRDLESNLKR 909
            ++ N+ +L+EN+ L+  L+   Q    N L +  N+T     E  K + + ++L   +  
Sbjct: 1082 KEYNKQILQENKKLKRKLNSNSQIPDINKL-QSENKT--LSQELFKLKDENQELLERVAT 1138

Query: 910  ITHEHQTLIVQKKKEIEDLEIEF---NTQIESAIRD--KKVLNEKYEKNIEYVTQL--EA 962
            +T     L  ++++E   L  +F   N   E  I+       + K      ++TQ   +A
Sbjct: 1139 MTLSLSQLEFEEEEETMLLSPQFDQLNNHTEEKIKSVISSPRSSKKRNRPVFLTQSLNDA 1198

Query: 963  QL-QEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINE 1010
            +L  E +   E ++ N  E +++N EL   H  +++ +   Y   Y  E
Sbjct: 1199 ELSSETEVKSEVISENHSEGSQIN-ELSKNHFSEEEIE--QYENSYEEE 1244



 Score = 60.1 bits (139), Expect = 5e-07
 Identities = 147/712 (20%), Positives = 286/712 (40%), Gaps = 69/712 (9%)

Query: 92   ESLANTLKQKEILMEKIKQYKELSKRSSTTI--VRXXXXXXXXXXXXXXXQLGDV----T 145
            E L    +Q E LME+ +  KE+  +S  ++   +               ++ DV     
Sbjct: 454  EELTQVKRQMEDLMEENENIKEILAKSVESLKKKKSEINDLKSLVENQKTEISDVEKSKE 513

Query: 146  HLSNTIKEKDNALSVLQVKMK-----------IMETTILDLQEKINE-KDQIIEAKNKAT 193
             L N I+++   +  L+ +++           +   T+   +E+ NE + Q ++ K    
Sbjct: 514  ELYNEIEQQKKEIEQLKKEIERNDMNFNNYRDMSNKTLRKTEEEKNEIERQFVKYKLDTN 573

Query: 194  TXXXXXXXXXXXXXXXXXE--DTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRIS 251
            T                 E  + +++++  Q+  I M+ E   + +   K+      +I 
Sbjct: 574  TESETYKTLQTTLTDRNDEISNLRKKVSDFQKEIIKMQEEMHSKSKDFDKNKAEFTNKIK 633

Query: 252  SLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEI- 310
            +LE+ N+ L +    IS ++++  ++ E                  Q IE +     EI 
Sbjct: 634  NLEKLNEDLRSQ--VISSQNTR--KKSEDMMEASMKQYENDILNLSQQIESNNSNHQEII 689

Query: 311  ----EEKGS----LEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSP 362
                EE G+    +E     ++ K+ E LE+    I     E+++K   +  + +  S  
Sbjct: 690  KQCKEESGNKIKEIEAEYEDKINKQKEKLENKIKDIEFQYSEIKSKYEEVNNQIQEASQM 749

Query: 363  SKK-GSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINK---NEIAKLEM---VIQ 415
             +   +  IS      T+++  S  +Q+  E L  +   K N+    ++ K+ M   +++
Sbjct: 750  KETFDNCCISLFGSIKTSNEFSSLINQMKEENLKLNELSKTNEILTGKLGKIYMANKILK 809

Query: 416  SLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDV 475
            S N +L     VIS + +           K         E+  + +  +L        ++
Sbjct: 810  SENANL-KNNLVISSQSSRKISDEFKNLSKKYNELNNSSENLTN-DNKTLNEKNQKLNEL 867

Query: 476  NEIAKVQEQLKQELNDEIKDVNVKDLIEK-------LKSAEEQITQLNDEIDAANKNMIK 528
            N      E LK    +E+   N K L EK        K  EE   +LN+E      N  K
Sbjct: 868  NNNLS-SEFLKLSSQNEVLTNNQKILEEKHNKLQNDHKQLEENFQKLNNEHQELTTNYEK 926

Query: 529  VKSNHKLKLKQMQKTID-----NFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQL 583
            +  NH+ KLK+  +T       + + V++  +   +L +E+ +++ +  E+  +   L+ 
Sbjct: 927  LTENHE-KLKKEYETATSELSISMNDVNELTEHYKQLKDEIFNINNQYNEIISDNERLKT 985

Query: 584  HLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDK 643
             L +     + ES+     I++EN  E   K++++ ES K  L  EL    ++ + +   
Sbjct: 986  EL-ELTKDELNESNNNLSKIKLEN--EEMSKSLNISESDKKKLENELEENNREIENISLS 1042

Query: 644  L-ADISQLQSDQVC---SEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDL 699
            L  +IS+    Q C      K      +ID LS   KE+    + +  + ++L   +   
Sbjct: 1043 LDKEISKNDELQKCLTKLSSKITDSSSRIDDLSERNKEMKEYNKQILQENKKLKRKLN-- 1100

Query: 700  ENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQF 751
             N +   +NKLQ+   EN  L+ +L K+  E   ELL ++     S  Q +F
Sbjct: 1101 SNSQIPDINKLQS---ENKTLSQELFKLKDEN-QELLERVATMTLSLSQLEF 1148


>UniRef50_A0D2T6 Cluster: Chromosome undetermined scaffold_35, whole
            genome shotgun sequence; n=1; Paramecium tetraurelia|Rep:
            Chromosome undetermined scaffold_35, whole genome shotgun
            sequence - Paramecium tetraurelia
          Length = 1023

 Score =  132 bits (319), Expect = 8e-29
 Identities = 178/898 (19%), Positives = 397/898 (44%), Gaps = 65/898 (7%)

Query: 734  ELLAKINHEEQSKIQTQFGIDAKIQE--RDLYIENI----ESELSKYKSRICRLEES--- 784
            EL  +IN  E  KI    G    +Q+  + L IEN     ++E+ + K     LE     
Sbjct: 66   ELQFQINAGELKKIDYLEGRIKVLQDAVKQLNIENRSQINQNEILRVKCDELELENQDLK 125

Query: 785  IAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEI 844
            +A +E++R  L    D     L + ++  + Y  Q  +L  +  V+ +    + + L+EI
Sbjct: 126  MARLENKR--LRELLDGAHDELSQAKQTIANYEDQLADLAIKDQVIKEQKDKINQLLVEI 183

Query: 845  EHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLE 904
            E   K  Q+ +   ++  +  + S   ++   N+   +  R+   +++   YQ +L++L 
Sbjct: 184  EFWKKRYQQLDTDRIKGIEEFKKSSETLR---NSQFNELRRSGSMQAQG--YQNELKNLR 238

Query: 905  SNLKRITHEHQTLI-----VQKKKEIEDLEI-EFNTQIESAIRDKKVLNEKYEKNIEYVT 958
              L+R+  E+  L      ++  K  ++ +  E NT++ES+ ++ K LN+   +  +   
Sbjct: 239  VQLERLQQENNELKDNIHQLESSKNGQNSQFKEVNTKLESSTKEIKRLNDILLQRGQQNK 298

Query: 959  QLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALL 1018
            QLE +++E +  +   N+  EE++K+  +L DK+  KQ  +  +   Q  N I +L  LL
Sbjct: 299  QLELRIKELERQVSEKNILKEEIDKLKQQLNDKN--KQLQEQHNQITQLNNRIAELERLL 356

Query: 1019 KQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHN 1078
             Q+ ++     Q++        +++   + ++A    K+EN+ ++++ + K + +     
Sbjct: 357  -QESKQYKEKIQQLQTEIAQLKAIIQGKDEEIAILKQKIENLTDQLKEIDKIIQEKYALE 415

Query: 1079 EELQILVREQDDQIKELKETKLTF-EMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXX 1137
             ++ +L  E + +  +LK  + T  E+     +     + +E +  D + +         
Sbjct: 416  NKVAMLATEIERKAAQLKNKEKTIDELRENLDQNNHTLAEVEQLQQDIDGLHLELKGKDD 475

Query: 1138 XXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLET-LNTELTGHDVVNQEQI 1196
                  ++E ++   E    QEQ ++L T++ +   K+  L + +  +    D   ++  
Sbjct: 476  L-----IKELDQKYHEALKYQEQVSQLETQVFDLQGKVAMLSSEIERQRIKLDKYKKDYD 530

Query: 1197 NQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQRE---ADFQKT 1253
             Q + K+  LN    +   ++ +      +  DQ+  E  + W+  L + +   ++ QKT
Sbjct: 531  GQ-QVKINDLNDMKFD-FDSMQDALQRYKAQEDQQQQEY-DSWRDILKKADLESSELQKT 587

Query: 1254 EHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKY 1313
            +  L  +    + +YE+L + ++   +    +   +E +     K QD E  +  +Q K 
Sbjct: 588  QETLSSEKQIAQDQYEKLTEQIKELNKLLQEERAKIEGLHKEIEKYQDLENKVYEMQNKT 647

Query: 1314 ADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEE 1373
            A +  +IE  R  ++++                    +   + +   +   +SI    +E
Sbjct: 648  AMLSAEIE--RRSVKEKTKQQQFDELSQLSKQQQEDLEKMAQIEQENETLNESIKKTQDE 705

Query: 1374 NAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDE 1433
             AQ++K                 + E KV  L+ ++E +   +  KT E +  L ++N E
Sbjct: 706  IAQMQKLQDETQEKLEKVLSERGNLENKVAMLSTEIERQSYRLKNKTEECS-QLNEKNQE 764

Query: 1434 -------FENVRQQLVEYEKRIEDLTYE-KESELAILRLKMHENANHYETMQKESEIERV 1485
                    +++  ++ E  +++E+L +   E++L  ++L    +A  +E  Q E+EI++ 
Sbjct: 765  LQGEILKLQDLPAEVEELSQQVEELRHSLNEADLKQVKLTQDLDAVAHEKAQIEAEIQKH 824

Query: 1486 KLIEELNVKITESVSLNKQVA---ELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITN 1542
            +   +L  ++TE     KQ+A   E  K++EEE +    +++ L   +++   L  +I  
Sbjct: 825  QDEIKLQQQLTEEA--KKQLANFTEKFKSVEEENSSLRALESKLSEYQMKTALLASQI-- 880

Query: 1543 LQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDLAMYMLHQRD 1600
                  A + K Q  +   S  +Q  D+   + ++ E +    + EL+  + +L+++D
Sbjct: 881  -----EAQNKKYQGKLDEMSALQQNFDDLKAHQLDVEDI----QGELERTLTILNEKD 929



 Score =  123 bits (297), Expect = 4e-26
 Identities = 177/834 (21%), Positives = 366/834 (43%), Gaps = 77/834 (9%)

Query: 476  NEIAKVQEQLK--QELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKS-- 531
            NE+  ++ QL+  Q+ N+E+KD N+  L         Q  ++N +++++ K + ++    
Sbjct: 232  NELKNLRVQLERLQQENNELKD-NIHQLESSKNGQNSQFKEVNTKLESSTKEIKRLNDIL 290

Query: 532  -NHKLKLKQMQKTIDNFSK-VSDSN---KEIVRLTEELHHLSQKVAELEEEKGNLQLHLV 586
                 + KQ++  I    + VS+ N   +EI +L ++L+  ++++ E   +   L   + 
Sbjct: 291  LQRGQQNKQLELRIKELERQVSEKNILKEEIDKLKQQLNDKNKQLQEQHNQITQLNNRIA 350

Query: 587  DYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLAD 646
            + +   + ES  YK+ I+       +LKAI     Q  D  +E+ IL+QK + + D+L +
Sbjct: 351  ELER-LLQESKQYKEKIQQLQTEIAQLKAII----QGKD--EEIAILKQKIENLTDQLKE 403

Query: 647  ISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDI 706
            I ++  ++   E K   L  +I+  +A  K     I+ L+ + +Q   T+ ++E  ++DI
Sbjct: 404  IDKIIQEKYALENKVAMLATEIERKAAQLKNKEKTIDELRENLDQNNHTLAEVEQLQQDI 463

Query: 707  MNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQ-FGIDAKIQERDLYIE 765
             + L   ++   DL  +L+    +K  E L     E+ S+++TQ F +  K+      IE
Sbjct: 464  -DGLHLELKGKDDLIKELD----QKYHEALK--YQEQVSQLETQVFDLQGKVAMLSSEIE 516

Query: 766  NIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVN 825
                +L KYK      +  I  + D ++  +   D L  Y  ++ +   EY    D    
Sbjct: 517  RQRIKLDKYKKDYDGQQVKINDLNDMKFDFDSMQDALQRYKAQEDQQQQEYDSWRD---- 572

Query: 826  RLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANR 885
                      +++K  L    E+ ELQK  + L  E Q  Q    D  +     +++ N+
Sbjct: 573  ----------ILKKADL----ESSELQKTQETLSSEKQIAQ----DQYEKLTEQIKELNK 614

Query: 886  TDLAESESTKYQTQLRDLE--SNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDK 943
              L + E  K +   +++E   +L+   +E Q        EIE   ++  T+ +    + 
Sbjct: 615  --LLQEERAKIEGLHKEIEKYQDLENKVYEMQNKTAMLSAEIERRSVKEKTK-QQQFDEL 671

Query: 944  KVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDK--HVQKQQTQSP 1001
              L+++ ++++E + Q+E + +    +I+     + ++ K+  E  +K   V  ++    
Sbjct: 672  SQLSKQQQEDLEKMAQIEQENETLNESIKKTQDEIAQMQKLQDETQEKLEKVLSERGNLE 731

Query: 1002 DYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENM- 1060
            +       EI + +  LK K EE   LN+K    Q   + +  D  +++ + + ++E + 
Sbjct: 732  NKVAMLSTEIERQSYRLKNKTEECSQLNEKNQELQGEILKL-QDLPAEVEELSQQVEELR 790

Query: 1061 ----EEEMQRVS-KQLLDSKQHNE-ELQILVREQDDQIKELKETKLTFEMNIPKTEGMII 1114
                E ++++V   Q LD+  H + +++  +++  D+IK   + +LT E           
Sbjct: 791  HSLNEADLKQVKLTQDLDAVAHEKAQIEAEIQKHQDEIK--LQQQLTEEAKKQLANFTEK 848

Query: 1115 SSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTK 1174
              ++E  +     ++            L  Q E +  + +  L E SA L     +    
Sbjct: 849  FKSVEEENSSLRALESKLSEYQMKTALLASQIEAQNKKYQGKLDEMSA-LQQNFDDLKAH 907

Query: 1175 IIQLETLNTELTGHDVVNQEQINQ---LKSKLEQLNTENDNLLSTVAELRSS---ISSAV 1228
             + +E +  EL     +  E+  +      K+++L  +   L     +L S    +SS V
Sbjct: 908  QLDVEDIQGELERTLTILNEKDKEHGLYDKKIQELEAQIKQLEDVKYQLESKMAMVSSEV 967

Query: 1229 DQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEE 1282
            ++  ++  +L K++  +      + E EL +Q     SK  Q L+     TQ+E
Sbjct: 968  ERVKYKYEKLQKEY-EENHQRLLEAEEEL-IQ----NSKEVQALEDELHHTQQE 1015



 Score =  116 bits (278), Expect = 7e-24
 Identities = 225/1027 (21%), Positives = 441/1027 (42%), Gaps = 115/1027 (11%)

Query: 557  IVRLTEELHHLSQKVAELEEE-KGNL-QLHLVDYDSGRMIESDVYKKMIEMENLAET--- 611
            I R+ EE+     K  +LE + + N  +L  +DY  GR+       K + +EN ++    
Sbjct: 48   ITRMQEEIDVWRNKFFQLELQFQINAGELKKIDYLEGRIKVLQDAVKQLNIENRSQINQN 107

Query: 612  ---RLKAISL-LESQKFDLVQ-ELHILQQKYDEVEDKLADISQL---QSDQVCS-EIKSV 662
               R+K   L LE+Q   + + E   L++  D   D+L+   Q      DQ+    IK  
Sbjct: 108  EILRVKCDELELENQDLKMARLENKRLRELLDGAHDELSQAKQTIANYEDQLADLAIKDQ 167

Query: 663  HLEEQIDALSASKKELALVIENLK-LDKEQLYGTIKDLENDKEDIMN------------K 709
             ++EQ D ++    E+    +  + LD +++ G I++ +   E + N            +
Sbjct: 168  VIKEQKDKINQLLVEIEFWKKRYQQLDTDRIKG-IEEFKKSSETLRNSQFNELRRSGSMQ 226

Query: 710  LQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKI--QTQFG-IDAKIQERDLYIEN 766
             Q Y  E  +L  +LE++  E  +EL   I+  E SK    +QF  ++ K++     I+ 
Sbjct: 227  AQGYQNELKNLRVQLERLQQEN-NELKDNIHQLESSKNGQNSQFKEVNTKLESSTKEIKR 285

Query: 767  IESELSKYKSRICRLEESIAVME---DRRYSLERKADQLGSYLQEKQKAYSEYTIQEDEL 823
            +   L +   +  +LE  I  +E     +  L+ + D+L   L +K K   E   Q  +L
Sbjct: 286  LNDILLQRGQQNKQLELRIKELERQVSEKNILKEEIDKLKQQLNDKNKQLQEQHNQITQL 345

Query: 824  VNRLAVL---MDHDRVVEKQLLEIEHENKEL----QKKNQ---ILLEENQNLQISLSDMQ 873
             NR+A L   +   +  ++++ +++ E  +L    Q K++   IL ++ +NL   L ++ 
Sbjct: 346  NNRIAELERLLQESKQYKEKIQQLQTEIAQLKAIIQGKDEEIAILKQKIENLTDQLKEID 405

Query: 874  QHYNALVEKANRTDLAESESTKYQTQLRDLESNL----KRITHEHQTL--IVQKKKEIED 927
            +         N+  +  +E  +   QL++ E  +    + +   + TL  + Q +++I+ 
Sbjct: 406  KIIQEKYALENKVAMLATEIERKAAQLKNKEKTIDELRENLDQNNHTLAEVEQLQQDIDG 465

Query: 928  LEIEFNTQIESAIRDKKVLNEKYEKNIEY---VTQLEAQLQEYKNNIENLNMNVEELNKM 984
            L +E   + +  I++   L++KY + ++Y   V+QLE Q+ + +  +  L+  +E   ++
Sbjct: 466  LHLELKGK-DDLIKE---LDQKYHEALKYQEQVSQLETQVFDLQGKVAMLSSEIER-QRI 520

Query: 985  NLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVS 1044
             L+   K    QQ +  D  +   +  +  +AL + K +E        +  Q  Y S   
Sbjct: 521  KLDKYKKDYDGQQVKINDLNDMKFDFDSMQDALQRYKAQE--------DQQQQEYDSW-- 570

Query: 1045 DYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEM 1104
                       K +    E+Q+  + L   KQ  ++    + EQ   IKEL   KL  E 
Sbjct: 571  ------RDILKKADLESSELQKTQETLSSEKQIAQDQYEKLTEQ---IKELN--KLLQEE 619

Query: 1105 NIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQE--QSA 1162
               K EG+     IE   D  N V             L  + E   ++E++  Q+  + +
Sbjct: 620  RA-KIEGL--HKEIEKYQDLENKV----YEMQNKTAMLSAEIERRSVKEKTKQQQFDELS 672

Query: 1163 KLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRS 1222
            +L+ + QE   K+ Q+E  N  L       Q++I Q++   ++   + + +LS    L +
Sbjct: 673  QLSKQQQEDLEKMAQIEQENETLNESIKKTQDEIAQMQKLQDETQEKLEKVLSERGNLEN 732

Query: 1223 SI---SSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQ-LSAFESKYEQLLDSVQSS 1278
             +   S+ ++++ + +    ++     E + +     L++Q L A   +  Q ++ ++ S
Sbjct: 733  KVAMLSTEIERQSYRLKNKTEECSQLNEKNQELQGEILKLQDLPAEVEELSQQVEELRHS 792

Query: 1279 TQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXX 1338
              E   K V + Q   L     +K +    +Q K+ D I   + L  E + +   F    
Sbjct: 793  LNEADLKQVKLTQ--DLDAVAHEKAQIEAEIQ-KHQDEIKLQQQLTEEAKKQLANFTEKF 849

Query: 1339 XXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDA 1398
                         LR       + Q ++ L  ++  AQ KK                +D 
Sbjct: 850  KSVEEENSS----LRALESKLSEYQMKTALLASQIEAQNKKYQGKLDEMSALQQ-NFDDL 904

Query: 1399 EAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDE----FENVRQQLVEYEKRIEDLTYE 1454
            +A      HQL+++D    Q   E T+T+    D+    ++   Q+L    K++ED+ Y+
Sbjct: 905  KA------HQLDVED---IQGELERTLTILNEKDKEHGLYDKKIQELEAQIKQLEDVKYQ 955

Query: 1455 KESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEE 1514
             ES++A++  ++      YE +QKE E    +L+E     I  S  +     EL+   ++
Sbjct: 956  LESKMAMVSSEVERVKYKYEKLQKEYEENHQRLLEAEEELIQNSKEVQALEDELHHT-QQ 1014

Query: 1515 EVAKTNE 1521
            E+A++ +
Sbjct: 1015 ELAQSRK 1021



 Score =  108 bits (260), Expect = 1e-21
 Identities = 199/916 (21%), Positives = 407/916 (44%), Gaps = 96/916 (10%)

Query: 215  KQQMTKMQENFIAMEAEWKDEKQRLLKD-IES-KDVRISSLEEANKLLEAARFEISLEHS 272
            K+Q  K+ +  + +E  WK   Q+L  D I+  ++ + SS    N      R   S++  
Sbjct: 170  KEQKDKINQLLVEIEF-WKKRYQQLDTDRIKGIEEFKKSSETLRNSQFNELRRSGSMQAQ 228

Query: 273  KLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLE 332
                EL+               L K +I      K     +       +   TK+I+ L 
Sbjct: 229  GYQNELKNLRVQLERLQQENNEL-KDNIHQLESSKNGQNSQFKEVNTKLESSTKEIKRLN 287

Query: 333  HLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSE 392
             +  Q  Q NK+LE ++  +    + VS  +     +   K   N  +K      QL  E
Sbjct: 288  DILLQRGQQNKQLELRIKEL---ERQVSEKNILKEEIDKLKQQLNDKNK------QL-QE 337

Query: 393  TLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQL 452
              NQ T  ++N N IA+LE ++Q  +K   +K   I +  T          GKD  IA L
Sbjct: 338  QHNQIT--QLN-NRIAELERLLQE-SKQYKEK---IQQLQTEIAQLKAIIQGKDEEIAIL 390

Query: 453  QLEHQQHMEGPSLIHVGTNTEDVNEIAK-VQEQLKQELNDEIKDVNVKDLIEKLKSAEEQ 511
                +Q +E          T+ + EI K +QE+   E    +    ++    +LK+ E+ 
Sbjct: 391  ----KQKIE--------NLTDQLKEIDKIIQEKYALENKVAMLATEIERKAAQLKNKEKT 438

Query: 512  ITQLNDEIDAANKNMIKVKSNHKL-KLKQMQKTIDNFSKVSDSNKEIVRLTEELHH---- 566
            I +L + +D         ++NH L +++Q+Q+ ID          ++++  ++ +H    
Sbjct: 439  IDELRENLD---------QNNHTLAEVEQLQQDIDGLHLELKGKDDLIKELDQKYHEALK 489

Query: 567  LSQKVAELEEEKGNLQLHLVDYDS---GRMIESDVYKK-----MIEMENLAETRLKAISL 618
              ++V++LE +  +LQ  +    S    + I+ D YKK      +++ +L + +    S+
Sbjct: 490  YQEQVSQLETQVFDLQGKVAMLSSEIERQRIKLDKYKKDYDGQQVKINDLNDMKFDFDSM 549

Query: 619  LESQKFDLVQELHILQQKYDEVED--KLADI--SQLQSDQVCSEIKSVHLEEQIDALSAS 674
             ++ +    QE    QQ+YD   D  K AD+  S+LQ  Q     +    ++Q + L+  
Sbjct: 550  QDALQRYKAQE-DQQQQEYDSWRDILKKADLESSELQKTQETLSSEKQIAQDQYEKLTEQ 608

Query: 675  KKELALVIENLKLDKEQLYGTI---KDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEK 731
             KEL  +++  +   E L+  I   +DLEN   ++ NK    +   ++     EK   ++
Sbjct: 609  IKELNKLLQEERAKIEGLHKEIEKYQDLENKVYEMQNKTA-MLSAEIERRSVKEKTKQQQ 667

Query: 732  ISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDR 791
              E L++++ ++Q  ++    I+ + +  +  I+  + E+++ +      +E +  +   
Sbjct: 668  FDE-LSQLSKQQQEDLEKMAQIEQENETLNESIKKTQDEIAQMQKLQDETQEKLEKVLSE 726

Query: 792  RYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKEL 851
            R +LE K   L + ++ +       T +  +L  +   L      ++    E+E  ++++
Sbjct: 727  RGNLENKVAMLSTEIERQSYRLKNKTEECSQLNEKNQELQGEILKLQDLPAEVEELSQQV 786

Query: 852  QKKNQILLEENQNLQISLSDMQQHYNALV-EKANRTDLAESESTKYQTQLRDLESNLKRI 910
            ++    L E +   Q+ L+   Q  +A+  EKA      E+E  K+Q +++ L+  L   
Sbjct: 787  EELRHSLNEADLK-QVKLT---QDLDAVAHEKAQ----IEAEIQKHQDEIK-LQQQLTEE 837

Query: 911  THEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNN 970
              +      +K K +E    E N+ +  A+  K  L+E   K     +Q+EAQ ++Y+  
Sbjct: 838  AKKQLANFTEKFKSVE----EENSSLR-ALESK--LSEYQMKTALLASQIEAQNKKYQGK 890

Query: 971  IEN---LNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIA 1027
            ++    L  N ++L    L++ D   + ++T +       +NE +K + L  +K +E+ A
Sbjct: 891  LDEMSALQQNFDDLKAHQLDVEDIQGELERTLT------ILNEKDKEHGLYDKKIQELEA 944

Query: 1028 LNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSK----QHNEELQI 1083
              +++ + +    S ++   S++ +   K E +++E +   ++LL+++    Q+++E+Q 
Sbjct: 945  QIKQLEDVKYQLESKMAMVSSEVERVKYKYEKLQKEYEENHQRLLEAEEELIQNSKEVQA 1004

Query: 1084 LVREQDDQIKELKETK 1099
            L  E     +EL +++
Sbjct: 1005 LEDELHHTQQELAQSR 1020



 Score = 84.6 bits (200), Expect = 2e-14
 Identities = 154/779 (19%), Positives = 332/779 (42%), Gaps = 75/779 (9%)

Query: 229  EAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXX 288
            E E +  ++ +LK  E  D     L + NK L+    +I+  ++++A ELE+        
Sbjct: 306  ELERQVSEKNILK--EEIDKLKQQLNDKNKQLQEQHNQITQLNNRIA-ELERLLQE---- 358

Query: 289  XXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENK 348
                   +KQ  E   + +TEI +  ++      E+    + +E+L  Q+++ +K ++ K
Sbjct: 359  -------SKQYKEKIQQLQTEIAQLKAIIQGKDEEIAILKQKIENLTDQLKEIDKIIQEK 411

Query: 349  LATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIA 408
             A     +   +   +K + L   K+   T  +++        E L+Q+        E+ 
Sbjct: 412  YALENKVAMLATEIERKAAQL---KNKEKTIDELR--------ENLDQNNH---TLAEVE 457

Query: 409  KLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQL-QLEHQQHMEGPSLIH 467
            +L+  I  L+ +L  K+ +I E D               L  Q+  L+ +  M    +  
Sbjct: 458  QLQQDIDGLHLELKGKDDLIKELDQKYHEALKYQEQVSQLETQVFDLQGKVAMLSSEIER 517

Query: 468  VGTNTEDVNEIAKVQEQLKQELNDEIKDV-NVKDLIEKLKSAEEQITQLNDEIDAANKNM 526
                 +   +    Q+    +LND   D  +++D +++ K+ E+Q  Q   E D+  +++
Sbjct: 518  QRIKLDKYKKDYDGQQVKINDLNDMKFDFDSMQDALQRYKAQEDQQQQ---EYDSW-RDI 573

Query: 527  IKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLV 586
            +K       +L++ Q+T+ +  +++    E  +LTE++  L++    L+EE+  ++    
Sbjct: 574  LKKADLESSELQKTQETLSSEKQIAQDQYE--KLTEQIKELNKL---LQEERAKIEGLHK 628

Query: 587  DYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLAD 646
            + +  + +E+ VY +M     +    ++  S+ E  K     EL  L ++  E  +K+A 
Sbjct: 629  EIEKYQDLENKVY-EMQNKTAMLSAEIERRSVKEKTKQQQFDELSQLSKQQQEDLEKMAQ 687

Query: 647  ISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDI 706
            I Q +++ +   IK    +++I  +   + E    +E +  ++  L   +  L  + E  
Sbjct: 688  IEQ-ENETLNESIKKT--QDEIAQMQKLQDETQEKLEKVLSERGNLENKVAMLSTEIERQ 744

Query: 707  MNKLQNYIQENMDLTDKLEKMSAE--KISELLAKINHEEQSKIQTQFGIDAKIQERDLYI 764
              +L+N  +E   L +K +++  E  K+ +L A++    Q   + +  ++    E DL  
Sbjct: 745  SYRLKNKTEECSQLNEKNQELQGEILKLQDLPAEVEELSQQVEELRHSLN----EADLKQ 800

Query: 765  ENIESELSKYKSRICRLEESIAVMEDR---RYSLERKADQLGSYLQEKQKAYSEYTIQED 821
              +  +L        ++E  I   +D    +  L  +A +  +   EK K+  E      
Sbjct: 801  VKLTQDLDAVAHEKAQIEAEIQKHQDEIKLQQQLTEEAKKQLANFTEKFKSVEEENSSLR 860

Query: 822  ELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNL------QISLSDMQQH 875
             L ++L+       ++  Q   IE +NK+ Q K   +    QN       Q+ + D+Q  
Sbjct: 861  ALESKLSEYQMKTALLASQ---IEAQNKKYQGKLDEMSALQQNFDDLKAHQLDVEDIQGE 917

Query: 876  YNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQ 935
                +   N  D    E   Y  ++++LE+ +K++           K ++E      +++
Sbjct: 918  LERTLTILNEKD---KEHGLYDKKIQELEAQIKQLE--------DVKYQLESKMAMVSSE 966

Query: 936  IESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQ 994
            +E      + L ++YE+N + + + E +L +    ++ L    +EL+    EL     Q
Sbjct: 967  VERVKYKYEKLQKEYEENHQRLLEAEEELIQNSKEVQALE---DELHHTQQELAQSRKQ 1022


>UniRef50_UPI0000E47346 Cluster: PREDICTED: similar to
            Golgi-associated microtubule-binding protein isoform 3,
            partial; n=2; Strongylocentrotus purpuratus|Rep:
            PREDICTED: similar to Golgi-associated
            microtubule-binding protein isoform 3, partial -
            Strongylocentrotus purpuratus
          Length = 2147

 Score =  132 bits (318), Expect = 1e-28
 Identities = 252/1412 (17%), Positives = 568/1412 (40%), Gaps = 113/1412 (8%)

Query: 162  QVKMKIMETTILDLQEKINEKDQIIE--AKNKATTXXXXXXXXXXXXXXXXXEDTKQQMT 219
            +++ + +E  ++ +++++ EKD+I++     K                    +D    + 
Sbjct: 593  EMEKQALEEVVIRMRDQLKEKDRILQDMTAEKGLMAVHKEHSEDLEEKVKTLQDNNASLL 652

Query: 220  KMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELE 279
            K +E    +  E  ++ +R+  +    D  IS + +A   LE    E+   +S + +++E
Sbjct: 653  KEKETAKRVNEEMAEKLKRIEGEKNDLDASISQITKAKDGLENRLHEVESRYSAIEEDME 712

Query: 280  QXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIE-EKGSLEIANMTELTKKIELLEHLNCQI 338
                             +Q +  + EEK ++E +   L+  + T L + I   + L  +I
Sbjct: 713  TSRGDM-----------EQELNRTREEKEQLETDLNQLDAQHQTALEQIISSRDKLIQEI 761

Query: 339  RQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDT 398
                KE E+++  +    K     ++       + +  +   +M+   S   ++ L+ + 
Sbjct: 762  ----KEKESQI--IDVNDKLAKQSAELEQSAADKAALEDEMEEMREDLSTSRADLLDSEQ 815

Query: 399  DKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQ 458
             K+     +  L   +Q++       E+  S K+           G     ++ ++E Q+
Sbjct: 816  MKQEQAVAMTTLRTKLQAMQD-----EHNESLKEFDEFRRESQLNGGGLAASKQEVEKQR 870

Query: 459  HMEGPSL-IHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLND 517
              +   L       ++ ++   K+Q    +E +      +V  L  +L     +I +LN 
Sbjct: 871  QADETDLPSREALQSQILDLTEKLQSLQSKEQSGVSPTESVAYLEHELSRTHHEIEELNK 930

Query: 518  EIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEE 577
             ID  +  + ++ SNH    K++++     + +   N+   R+ EE+    + +     E
Sbjct: 931  SIDERDAKLQEMNSNHSEHSKRLEQKAAEVTALETENE---RIQEEVKSRDEVLTRSHSE 987

Query: 578  KGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISL-LESQKFDLVQELHILQQK 636
               LQ  L    SG     +  ++   +    +     +S+ L S+K  L   +   ++ 
Sbjct: 988  LMKLQADLAAIKSGAERRENAQEQERTLAEQLQKTCDGLSVELNSKKELLESVIESKKEL 1047

Query: 637  YDEVEDKLADISQLQSDQVCSEIKSVHL-EEQIDALSASKKELALVIENLKLDKEQLYGT 695
             D +E K  D+  L +D+     K+V   +++I  L+A  KE+  V   L+  KE     
Sbjct: 1048 EDLIEQKEEDVRAL-ADENTHYFKNVEKSKDKIGELTAKVKEMENVDRQLQETKENFEKL 1106

Query: 696  IKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDA 755
              +LE  K ++ +K+ +  +E+++ T  L K     + + LA+  H+E + ++ +  +  
Sbjct: 1107 TGELERTKSEL-SKMSSSGEEHLETTHTL-KEEVNNLKKNLAQ--HQESTGVEKE-NLQT 1161

Query: 756  KIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSE 815
            K  E    ++    ++S+    +   E  ++ ++    S+++      + L E  +  + 
Sbjct: 1162 KEDELTEELKESTQKISELNEELHAAELELSGVQAELESVQKTMAAQETQLSESNERINV 1221

Query: 816  YTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQH 875
               +  +L +++  L D  +V E     ++    +L +K+ I+ E  + L++S + ++  
Sbjct: 1222 KEAEISQLKSQIESLRDQSKVDESSADAVDQLQTDLIEKSAIINELQKELEVSRAGLESQ 1281

Query: 876  YNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQ 935
                 E     D   S      TQLR+                  +KK +++  +E+ +Q
Sbjct: 1282 LQTFQESIQNKDNEISRLDSSLTQLRN------------------QKKSLDESLVEYESQ 1323

Query: 936  IESAIRDKKVLNEKYEKNIEYVTQLEAQLQE-YKNNIENLNMNVEELNKMNLELIDKH-V 993
            IE   R     +E   +  E V  +  QLQ+  K  ++N  MN+    ++   L      
Sbjct: 1324 IEDLQRTNLQKDEDVNRLREEVGNITTQLQQPAKQPLQNGEMNISVSERIEDALPPSSPF 1383

Query: 994  QKQQTQSPDYTEQYINEINK-LNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQ 1052
             K  T      +  I++  K    +++++++EI  L  +    + S ++ +S+ +S    
Sbjct: 1384 SKSPTGVFQGQDGSISDNEKHYEKIIQEREKEISMLQHE----RQSLLTSLSE-KSTSTM 1438

Query: 1053 FTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKET--KLTFEMNIPKTE 1110
              + L ++ +   +V  + L+S++H  ++  ++ E+  +   LK    KL   ++  K  
Sbjct: 1439 GNSVLVDLHKNQMKV--KTLESERH--QMMTVLNEKTREASNLKNEVHKLVKVISAQK-- 1492

Query: 1111 GMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQE 1170
                 S +E   +D   +               +      IQ++ +  E   + NT L  
Sbjct: 1493 -----SALEKAQEDVKELHNASRGPRDDMQKEALHNLSRIIQDKDLEIEALKQKNTSL-- 1545

Query: 1171 CYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQ 1230
                   LE L +E       N  QI+ + S+ E+L  EN  L     +L  SI     Q
Sbjct: 1546 -------LEVLQSEAPS----NSSQISGVLSESEKLQKENTVLKEERDQLVVSIHQK-HQ 1593

Query: 1231 RGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQE--ETNKIV- 1287
                  E  ++ +     + QK   +L     A +SK ++L +S+  S  E  E++++  
Sbjct: 1594 ESLAYYEEVQRLVGIVNGEVQK-HSDLEKHHGALQSKMDELTESMNQSKMELNESSRVTG 1652

Query: 1288 TMEQVTSLQNKL-QDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXX 1346
            ++E+   +Q +L ++ E  ++ L +   ++  ++E L  ++E  K               
Sbjct: 1653 SLEEELEIQKQLVEELENQVQLLDDSGTEMTKRMEELE-KLEASKTNELGEKENELAHLQ 1711

Query: 1347 XXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELT 1406
                +L+T       + E++++       QL                 + D  +++    
Sbjct: 1712 HMLDELKTRRAP---IIEETVVKAEMAPVQLSAPPVQYEQKMQEKDAEIADLRSRLQPQQ 1768

Query: 1407 HQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESE-LAILRLK 1465
               ++ +  +  K H+  +   +  D+ E+    L+E +  ++D + E E + L I  L+
Sbjct: 1769 VTPQVSEDMVSLKEHDGELASVK--DQLESQGHALLEMDGLVKDRSMELEQKKLEIATLR 1826

Query: 1466 MHENANHYETMQKESEIER-VKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQT 1524
               +      + + + +++    +++L+V       L  +  E N         T ++  
Sbjct: 1827 QQIDQQDQAILDQNATLQKHTSDLQQLHV------DLKAKTEEANTLRHH----TQQISM 1876

Query: 1525 ALENQEIEIVTLNDEITNLQNMVRASSSKIQK 1556
             L+  E E+   + EITN Q+MV     ++++
Sbjct: 1877 RLQAVEQELARAHQEITNQQHMVLNKDGELRQ 1908



 Score =  109 bits (263), Expect = 5e-22
 Identities = 222/1182 (18%), Positives = 502/1182 (42%), Gaps = 113/1182 (9%)

Query: 475  VNEIAKVQEQLKQELND-EIKDVNVKDLIEKLKS-AEEQITQLNDEIDAANKNMIKVKSN 532
            +++I K ++ L+  L++ E +   +++ +E  +   E+++ +  +E +    ++ ++ + 
Sbjct: 683  ISQITKAKDGLENRLHEVESRYSAIEEDMETSRGDMEQELNRTREEKEQLETDLNQLDAQ 742

Query: 533  HKLKLKQMQKTIDNF--------SKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLH 584
            H+  L+Q+  + D          S++ D N ++ + + EL   +   A LE+E   ++  
Sbjct: 743  HQTALEQIISSRDKLIQEIKEKESQIIDVNDKLAKQSAELEQSAADKAALEDEMEEMRED 802

Query: 585  LVDYDSGRMIESDVYKK--MIEMENLAETRLKAI------SLLESQKFDLVQELH---IL 633
            L       +++S+  K+   + M  L  T+L+A+      SL E  +F    +L+   + 
Sbjct: 803  L-STSRADLLDSEQMKQEQAVAMTTL-RTKLQAMQDEHNESLKEFDEFRRESQLNGGGLA 860

Query: 634  QQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLY 693
              K +  + + AD + L S +     + + L E++ +L + ++      E++   + +L 
Sbjct: 861  ASKQEVEKQRQADETDLPSREALQS-QILDLTEKLQSLQSKEQSGVSPTESVAYLEHELS 919

Query: 694  GT---IKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQ 750
             T   I++L    ++   KLQ     + + + +LE+ +AE  +  L   N   Q +++++
Sbjct: 920  RTHHEIEELNKSIDERDAKLQEMNSNHSEHSKRLEQKAAEVTA--LETENERIQEEVKSR 977

Query: 751  FGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQ 810
               D  +      +  ++++L+  KS   R E +          L++  D L   L  K+
Sbjct: 978  ---DEVLTRSHSELMKLQADLAAIKSGAERRENAQEQERTLAEQLQKTCDGLSVELNSKK 1034

Query: 811  KAYSEYTIQEDELVNRLAVLMDHDRVV-EKQLLEIEHENKELQKKNQIL--LEENQNLQI 867
            +        + EL + +    +  R + ++     ++  K   K  ++   ++E +N+  
Sbjct: 1035 ELLESVIESKKELEDLIEQKEEDVRALADENTHYFKNVEKSKDKIGELTAKVKEMENVDR 1094

Query: 868  SLSDMQQHYNALVEKANRTD-----LAESESTKYQTQ--LRDLESNLKRITHEHQTLIVQ 920
             L + ++++  L  +  RT      ++ S     +T   L++  +NLK+   +HQ     
Sbjct: 1095 QLQETKENFEKLTGELERTKSELSKMSSSGEEHLETTHTLKEEVNNLKKNLAQHQESTGV 1154

Query: 921  KKKEIEDLEIEFNTQIESAIRDKKVLNEKY----------EKNIEYVTQ-LEAQLQEYKN 969
            +K+ ++  E E   +++ + +    LNE+           +  +E V + + AQ  +   
Sbjct: 1155 EKENLQTKEDELTEELKESTQKISELNEELHAAELELSGVQAELESVQKTMAAQETQLSE 1214

Query: 970  NIENLNMNVEELNKMNLELIDKHVQ-KQQTQSPDYTEQYINEINKLNALLKQKDEEIIAL 1028
            + E +N+   E++++  ++     Q K    S D  +Q   ++ + +A++ +  +E+   
Sbjct: 1215 SNERINVKEAEISQLKSQIESLRDQSKVDESSADAVDQLQTDLIEKSAIINELQKELEVS 1274

Query: 1029 NQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQ 1088
               + +   ++   + + ++++++  + L  +  + + + + L++ +   E+LQ    ++
Sbjct: 1275 RAGLESQLQTFQESIQNKDNEISRLDSSLTQLRNQKKSLDESLVEYESQIEDLQRTNLQK 1334

Query: 1089 DDQIKELKET--KLTFEMNIPKTE-------GMIISSTIE---PMSDDANNVDXXXXXXX 1136
            D+ +  L+E    +T ++  P  +        + +S  IE   P S   +          
Sbjct: 1335 DEDVNRLREEVGNITTQLQQPAKQPLQNGEMNISVSERIEDALPPSSPFSKSPTGVFQGQ 1394

Query: 1137 XXXXXLKVQEEEEFIQER----SVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVN 1192
                    +  E+ IQER    S+LQ +   L T L E  T  +    L         V 
Sbjct: 1395 DGSISDNEKHYEKIIQEREKEISMLQHERQSLLTSLSEKSTSTMGNSVLVDLHKNQMKVK 1454

Query: 1193 --QEQINQLKSKLEQLNTENDNLLSTVAELRSSIS---SAVDQRGFEIAELWKQHLAQRE 1247
              + + +Q+ + L +   E  NL + V +L   IS   SA+++   ++ EL       R+
Sbjct: 1455 TLESERHQMMTVLNEKTREASNLKNEVHKLVKVISAQKSALEKAQEDVKELHNASRGPRD 1514

Query: 1248 ADFQKTE-HELR-------VQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKL 1299
             D QK   H L        +++ A + K   LL+ +QS     +++I     V S   KL
Sbjct: 1515 -DMQKEALHNLSRIIQDKDLEIEALKQKNTSLLEVLQSEAPSNSSQI---SGVLSESEKL 1570

Query: 1300 QDKEEHLRNLQEKYADVINQI--EILRSEIEDEK-VAFXXXXXXXXXXXXXXXXDLRTEN 1356
            Q +   L+  +++    I+Q   E L    E ++ V                   L+++ 
Sbjct: 1571 QKENTVLKEERDQLVVSIHQKHQESLAYYEEVQRLVGIVNGEVQKHSDLEKHHGALQSKM 1630

Query: 1357 QSYKQMQEQSILNINEEN---AQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKD 1413
                +   QS + +NE +     L++              +V   +    E+T ++E  +
Sbjct: 1631 DELTESMNQSKMELNESSRVTGSLEEELEIQKQLVEELENQVQLLDDSGTEMTKRMEELE 1690

Query: 1414 SEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEK--ESELAILRLKMHENAN 1471
                 KT+E    L ++ +E  +++  L E + R   +  E   ++E+A ++L       
Sbjct: 1691 KLEASKTNE----LGEKENELAHLQHMLDELKTRRAPIIEETVVKAEMAPVQLSAPPVQY 1746

Query: 1472 HYETMQKESEIE--RVKLI-EELNVKITES-VSLNKQVAEL----------NKALEEEVA 1517
              +  +K++EI   R +L  +++  +++E  VSL +   EL            AL E   
Sbjct: 1747 EQKMQEKDAEIADLRSRLQPQQVTPQVSEDMVSLKEHDGELASVKDQLESQGHALLEMDG 1806

Query: 1518 KTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVS 1559
               +    LE +++EI TL  +I      +   ++ +QKH S
Sbjct: 1807 LVKDRSMELEQKKLEIATLRQQIDQQDQAILDQNATLQKHTS 1848



 Score =  102 bits (245), Expect = 7e-20
 Identities = 198/1012 (19%), Positives = 422/1012 (41%), Gaps = 76/1012 (7%)

Query: 146  HLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXX 205
            HL  T   K+   ++ +   +  E+T ++ +    ++D++ E + K +T           
Sbjct: 1127 HLETTHTLKEEVNNLKKNLAQHQESTGVEKENLQTKEDELTE-ELKESTQKISELNEELH 1185

Query: 206  XXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRL-LKDIESKDVR--ISSLEEANKLLEA 262
                     + ++  +Q+   A E +  +  +R+ +K+ E   ++  I SL + +K+ E+
Sbjct: 1186 AAELELSGVQAELESVQKTMAAQETQLSESNERINVKEAEISQLKSQIESLRDQSKVDES 1245

Query: 263  ARFEIS------LEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIE----- 311
            +   +       +E S +  EL++                ++SI+    E + ++     
Sbjct: 1246 SADAVDQLQTDLIEKSAIINELQKELEVSRAGLESQLQTFQESIQNKDNEISRLDSSLTQ 1305

Query: 312  ---EKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTE-SKAVSSPSKKGS 367
               +K SL+  ++ E   +IE L+  N Q  +    L  ++  + T+  +    P + G 
Sbjct: 1306 LRNQKKSLD-ESLVEYESQIEDLQRTNLQKDEDVNRLREEVGNITTQLQQPAKQPLQNGE 1364

Query: 368  PLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYV 427
              IS       A    SP+S+ S   + Q  D  I+ NE    E +IQ   K++   ++ 
Sbjct: 1365 MNISVSERIEDALPPSSPFSK-SPTGVFQGQDGSISDNE-KHYEKIIQEREKEISMLQHE 1422

Query: 428  ISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDV-NEIAKVQEQLK 486
                 T          G   L+      H+  M+  +L         V NE  +    LK
Sbjct: 1423 RQSLLTSLSEKSTSTMGNSVLVDL----HKNQMKVKTLESERHQMMTVLNEKTREASNLK 1478

Query: 487  QELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDN 546
             E++  +K ++ +     L+ A+E + +L++       +M K ++ H L      K ++ 
Sbjct: 1479 NEVHKLVKVISAQK--SALEKAQEDVKELHNASRGPRDDMQK-EALHNLSRIIQDKDLE- 1534

Query: 547  FSKVSDSNKEIVR-LTEELHHLSQKVAELEEEKGNLQLH--LVDYDSGRMIESDVYKKMI 603
               +   N  ++  L  E    S +++ +  E   LQ    ++  +  +++ S   K   
Sbjct: 1535 IEALKQKNTSLLEVLQSEAPSNSSQISGVLSESEKLQKENTVLKEERDQLVVSIHQKHQE 1594

Query: 604  EMENLAET-RLKAISLLESQKFDLVQELH-ILQQKYDEVEDKLADISQLQSDQVCSEIKS 661
             +    E  RL  I   E QK   +++ H  LQ K DE+ + +   S+++ ++  S   +
Sbjct: 1595 SLAYYEEVQRLVGIVNGEVQKHSDLEKHHGALQSKMDELTESMNQ-SKMELNE--SSRVT 1651

Query: 662  VHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKL---QNYIQENM 718
              LEE+++      +EL   ++ L     ++   +++LE  +    N+L   +N +    
Sbjct: 1652 GSLEEELEIQKQLVEELENQVQLLDDSGTEMTKRMEELEKLEASKTNELGEKENELAHLQ 1711

Query: 719  DLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRI 778
             + D+L+   A  I E + K               + K+QE+D       +E++  +SR+
Sbjct: 1712 HMLDELKTRRAPIIEETVVKAEMAPVQLSAPPVQYEQKMQEKD-------AEIADLRSRL 1764

Query: 779  CRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVE 838
               + +  V ED   SL+    +L S ++++ ++     ++ D LV       D    +E
Sbjct: 1765 QPQQVTPQVSEDM-VSLKEHDGELAS-VKDQLESQGHALLEMDGLVK------DRSMELE 1816

Query: 839  KQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQT 898
            ++ LEI    +++ +++Q +L++N  LQ   SD+QQ +  L  K    +     + +   
Sbjct: 1817 QKKLEIATLRQQIDQQDQAILDQNATLQKHTSDLQQLHVDLKAKTEEANTLRHHTQQISM 1876

Query: 899  QLRDLESNLKRITHE---HQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIE 955
            +L+ +E  L R   E    Q +++ K  E+  L+ +  +++ + +R         EK+ E
Sbjct: 1877 RLQAVEQELARAHQEITNQQHMVLNKDGELRQLQ-DLMSRMSAEVR---------EKDFE 1926

Query: 956  YVTQLEAQLQEYKNNIENLNMNVE-ELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKL 1014
             +T L  + +     +++ + +V+ E+ ++  E      Q Q+ Q          E  + 
Sbjct: 1927 -LTALRDKCKTLAKLVDDKDTDVQGEVRRLLGEAEAMQTQAQRFQQERDQAMMALEKCQR 1985

Query: 1015 NALLKQKDEEIIALN-QKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQ-RVSKQLL 1072
            + LL Q++  +   N QK+        + +   E    Q   + E  E+E++ R+S    
Sbjct: 1986 DLLLLQEEAAMRGGNEQKLMRELERLRNHLIQMEDTYTQEALQAEEREKELRNRLSMAEE 2045

Query: 1073 DSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDD 1124
             +   +  +Q + +E   QI  L++      MN  K   ++  S ++  S++
Sbjct: 2046 HAHSSSSAVQSVSKEASAQIDSLQDQ--LGAMNEQKDHALMQLSMVQSESEE 2095



 Score = 98.3 bits (234), Expect = 2e-18
 Identities = 226/1197 (18%), Positives = 483/1197 (40%), Gaps = 116/1197 (9%)

Query: 483  EQLKQELNDEIKDVNVKDL--IEKLKS----AEEQITQLNDE--IDAANKNMIK--VKSN 532
            E L   LN ++K+++ +D    E+  S    +E ++T +  E  +D+  +  ++  V+  
Sbjct: 438  EALITNLNQKVKELSGQDPQGSEQRPSDPSQSESELTLVTGESDLDSLPQGGVEDGVQVR 497

Query: 533  HKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNL--QLHLVDYDS 590
              +  ++ Q   D+ S  SD +  +         LS     L E K +L      V +D 
Sbjct: 498  RHISYRRPQSPTDS-SVASDLSSSVREGWTSETELSSDGGFLTEGKQSLLENSDAVSFD- 555

Query: 591  GRMIESDVYKKMIE-MENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQ 649
            G   +S ++  + E     A+   + ++  E  + D   E   L++    + D+L +  +
Sbjct: 556  GEYDDSIMFAGIKEKFPEAADAFKQQLNQFEMVRADWEMEKQALEEVVIRMRDQLKEKDR 615

Query: 650  LQSDQVCSE-IKSVH------LEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLEND 702
            +  D    + + +VH      LEE++  L  +   L    E  K   E++   +K +E +
Sbjct: 616  ILQDMTAEKGLMAVHKEHSEDLEEKVKTLQDNNASLLKEKETAKRVNEEMAEKLKRIEGE 675

Query: 703  KEDI----------MNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFG 752
            K D+           + L+N + E       +E+       ++  ++N   + K Q +  
Sbjct: 676  KNDLDASISQITKAKDGLENRLHEVESRYSAIEEDMETSRGDMEQELNRTREEKEQLETD 735

Query: 753  IDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKA 812
            ++    +    +E I S   K    I   E  I  + D+   L +++ +L     +K   
Sbjct: 736  LNQLDAQHQTALEQIISSRDKLIQEIKEKESQIIDVNDK---LAKQSAELEQSAADKAAL 792

Query: 813  YSEYTIQEDELVNRLAVLMDHDRVVEKQ----------LLEIEHENKELQKKNQILLEEN 862
              E     ++L    A L+D +++ ++Q          L  ++ E+ E  K+      E+
Sbjct: 793  EDEMEEMREDLSTSRADLLDSEQMKQEQAVAMTTLRTKLQAMQDEHNESLKEFDEFRRES 852

Query: 863  QNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKK 922
            Q     L+  +Q       +A+ TDL   E+   Q+Q+ DL   L+ +  + Q+  V   
Sbjct: 853  QLNGGGLAASKQEVEK-QRQADETDLPSREA--LQSQILDLTEKLQSLQSKEQS-GVSPT 908

Query: 923  KEIEDLEIEFN------TQIESAI--RDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENL 974
            + +  LE E +       ++  +I  RD K L E    + E+  +LE +  E    +E  
Sbjct: 909  ESVAYLEHELSRTHHEIEELNKSIDERDAK-LQEMNSNHSEHSKRLEQKAAEV-TALETE 966

Query: 975  NMNVEELNKMNLELIDK-HVQKQQTQS-----PDYTEQYINEINKLNALLKQKDEEIIAL 1028
            N  ++E  K   E++ + H +  + Q+         E+  N   +   L +Q  +    L
Sbjct: 967  NERIQEEVKSRDEVLTRSHSELMKLQADLAAIKSGAERRENAQEQERTLAEQLQKTCDGL 1026

Query: 1029 NQKINNAQVSYMSMV---SDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILV 1085
            + ++N+ +    S++    + E  + Q    +  + +E     K +  SK    EL   V
Sbjct: 1027 SVELNSKKELLESVIESKKELEDLIEQKEEDVRALADENTHYFKNVEKSKDKIGELTAKV 1086

Query: 1086 REQDDQIKELKET-----KLTFEMNIPKTEGMIISS-------TIEPMSDDANNVDXXXX 1133
            +E ++  ++L+ET     KLT E+   K+E   +SS       T   + ++ NN+     
Sbjct: 1087 KEMENVDRQLQETKENFEKLTGELERTKSELSKMSSSGEEHLETTHTLKEEVNNLKKNLA 1146

Query: 1134 XXXXXXXXLK--VQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVV 1191
                     K  +Q +E+ + E   L+E + K++   +E +   ++L  +  EL      
Sbjct: 1147 QHQESTGVEKENLQTKEDELTEE--LKESTQKISELNEELHAAELELSGVQAELESVQKT 1204

Query: 1192 NQEQINQLKSKLEQLNTENDNLLSTVAELRS-SISSAVDQRGFEIAELWKQHLAQREADF 1250
               Q  QL    E++N +   +    +++ S    S VD+   +  +  +  L ++ A  
Sbjct: 1205 MAAQETQLSESNERINVKEAEISQLKSQIESLRDQSKVDESSADAVDQLQTDLIEKSAII 1264

Query: 1251 QKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQ 1310
             + + EL V  +  ES+ +   +S+Q+   E          ++ L + L       ++L 
Sbjct: 1265 NELQKELEVSRAGLESQLQTFQESIQNKDNE----------ISRLDSSLTQLRNQKKSLD 1314

Query: 1311 EKYADVINQIEIL-RSEIE-DEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSIL 1368
            E   +  +QIE L R+ ++ DE V                      +N        + I 
Sbjct: 1315 ESLVEYESQIEDLQRTNLQKDEDVNRLREEVGNITTQLQQPAKQPLQNGEMNISVSERIE 1374

Query: 1369 NINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLT 1428
            +    ++   KS              ++D E    ++  + E + S +  +      +L+
Sbjct: 1375 DALPPSSPFSKSPTGVFQGQDGS---ISDNEKHYEKIIQEREKEISMLQHERQSLLTSLS 1431

Query: 1429 QRNDEF--ENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVK 1486
            +++      +V   L + + +++ L  E+   + +L  K  E +N    + K      VK
Sbjct: 1432 EKSTSTMGNSVLVDLHKNQMKVKTLESERHQMMTVLNEKTREASNLKNEVHK-----LVK 1486

Query: 1487 LIEELNVKITESVSLNKQVAELNKALEEEVAK--TNEMQTALENQEIEIVTLNDEITNLQ 1544
            +I      + ++    K++   ++   +++ K   + +   ++++++EI  L  + T+L 
Sbjct: 1487 VISAQKSALEKAQEDVKELHNASRGPRDDMQKEALHNLSRIIQDKDLEIEALKQKNTSLL 1546

Query: 1545 NMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDLAMYMLHQRDV 1601
             ++++ +      +S      +    Q +NT+ KE      R +L ++++  HQ  +
Sbjct: 1547 EVLQSEAPSNSSQIS--GVLSESEKLQKENTVLKE-----ERDQLVVSIHQKHQESL 1596



 Score = 79.4 bits (187), Expect = 8e-13
 Identities = 237/1276 (18%), Positives = 518/1276 (40%), Gaps = 152/1276 (11%)

Query: 168  METTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIA 227
            +++ ILDL EK+    Q  E    + T                 E+  + + +       
Sbjct: 883  LQSQILDLTEKLQSL-QSKEQSGVSPTESVAYLEHELSRTHHEIEELNKSIDERDAKLQE 941

Query: 228  MEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXX 287
            M +   +  +RL    E K   +++LE  N+ ++    E+      L +   +       
Sbjct: 942  MNSNHSEHSKRL----EQKAAEVTALETENERIQE---EVKSRDEVLTRSHSELMKLQAD 994

Query: 288  XXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELEN 347
                    A++      +E+T  E+          EL  K ELLE     + ++ KELE+
Sbjct: 995  LAAIKSG-AERRENAQEQERTLAEQLQKTCDGLSVELNSKKELLE----SVIESKKELED 1049

Query: 348  KLATMGTESKAVSSPSK---KGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINK 404
             +     + +A++  +    K       K G  TA K+K        E  N D   +  K
Sbjct: 1050 LIEQKEEDVRALADENTHYFKNVEKSKDKIGELTA-KVK--------EMENVDRQLQETK 1100

Query: 405  NEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHME--G 462
                KL   ++    +L       S+  +               +  L+    QH E  G
Sbjct: 1101 ENFEKLTGELERTKSEL-------SKMSSSGEEHLETTHTLKEEVNNLKKNLAQHQESTG 1153

Query: 463  PSLIHVGTNTEDVNEIAKVQEQLKQELNDEIK--DVNVKDLIEKLKSAEEQITQLNDEID 520
                ++ T  +++ E  K   Q   ELN+E+   ++ +  +  +L+S ++ +     ++ 
Sbjct: 1154 VEKENLQTKEDELTEELKESTQKISELNEELHAAELELSGVQAELESVQKTMAAQETQLS 1213

Query: 521  AANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIV-RLTEELHHLSQKVAELEEE-- 577
             +N+  I VK     +LK   +++ + SKV +S+ + V +L  +L   S  + EL++E  
Sbjct: 1214 ESNER-INVKEAEISQLKSQIESLRDQSKVDESSADAVDQLQTDLIEKSAIINELQKELE 1272

Query: 578  --KGNLQLHLVDY-DSGRMIESDVYK---KMIEMENLAETRLKAISLLESQKFDL----V 627
              +  L+  L  + +S +  ++++ +    + ++ N  ++  +++   ESQ  DL    +
Sbjct: 1273 VSRAGLESQLQTFQESIQNKDNEISRLDSSLTQLRNQKKSLDESLVEYESQIEDLQRTNL 1332

Query: 628  QELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKL 687
            Q+   + +  +EV +    + Q     + +   ++ + E+I+         +     +  
Sbjct: 1333 QKDEDVNRLREEVGNITTQLQQPAKQPLQNGEMNISVSERIEDALPPSSPFSKSPTGVFQ 1392

Query: 688  DKEQLYGTIKDLENDKEDIMNKLQNYIQ----ENMDLTDKLEKMSAEKISELLAKINHEE 743
             ++   G+I D E   E I+ + +  I     E   L   L + S   +   +    H+ 
Sbjct: 1393 GQD---GSISDNEKHYEKIIQEREKEISMLQHERQSLLTSLSEKSTSTMGNSVLVDLHKN 1449

Query: 744  QSKIQT----QFGIDAKIQERDLYIENIESELSKY-------KSRICRLEESIAVMEDR- 791
            Q K++T    +  +   + E+     N+++E+ K        KS + + +E +  + +  
Sbjct: 1450 QMKVKTLESERHQMMTVLNEKTREASNLKNEVHKLVKVISAQKSALEKAQEDVKELHNAS 1509

Query: 792  ---RYSLERKA-DQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHE 847
               R  ++++A   L   +Q+K     E    + +  + L VL         Q+  +  E
Sbjct: 1510 RGPRDDMQKEALHNLSRIIQDKDL---EIEALKQKNTSLLEVLQSEAPSNSSQISGVLSE 1566

Query: 848  NKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANR-TDLAESESTKYQTQLRD---L 903
            +++LQK+N +L EE   L +S+    Q   A  E+  R   +   E  K+    +    L
Sbjct: 1567 SEKLQKENTVLKEERDQLVVSIHQKHQESLAYYEEVQRLVGIVNGEVQKHSDLEKHHGAL 1626

Query: 904  ESNLKRIT---HEHQTLIVQKKKEIEDLEIEFNTQ---IESAIRDKKVLNE---KYEKNI 954
            +S +  +T   ++ +  + +  +    LE E   Q   +E      ++L++   +  K +
Sbjct: 1627 QSKMDELTESMNQSKMELNESSRVTGSLEEELEIQKQLVEELENQVQLLDDSGTEMTKRM 1686

Query: 955  EYVTQLEA----QLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINE 1010
            E + +LEA    +L E +N + +L   ++EL      +I++ V K +      +   +  
Sbjct: 1687 EELEKLEASKTNELGEKENELAHLQHMLDELKTRRAPIIEETVVKAEMAPVQLSAPPVQY 1746

Query: 1011 INKLNALLKQKDEEIIALNQKINNAQVSYM---SMVS--DYESKLAQFTTKLENMEE--- 1062
              K+    ++KD EI  L  ++   QV+      MVS  +++ +LA    +LE+      
Sbjct: 1747 EQKM----QEKDAEIADLRSRLQPQQVTPQVSEDMVSLKEHDGELASVKDQLESQGHALL 1802

Query: 1063 EMQRVSK-QLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPM 1121
            EM  + K + ++ +Q   E+  L ++ D Q + + +   T + +    + + +   ++  
Sbjct: 1803 EMDGLVKDRSMELEQKKLEIATLRQQIDQQDQAILDQNATLQKHTSDLQQLHVD--LKAK 1860

Query: 1122 SDDANNVDXXXXXXXXXXXXLKVQ----EEEEFIQERSVL---------QEQSAKLNTEL 1168
            +++AN +             ++ +     +E   Q+  VL         Q+  ++++ E+
Sbjct: 1861 TEEANTLRHHTQQISMRLQAVEQELARAHQEITNQQHMVLNKDGELRQLQDLMSRMSAEV 1920

Query: 1169 QECYTKIIQL----ETLNTELTGHDVVNQEQINQLKSKLEQLNT-------ENDNLLSTV 1217
            +E   ++  L    +TL   +   D   Q ++ +L  + E + T       E D  +  +
Sbjct: 1921 REKDFELTALRDKCKTLAKLVDDKDTDVQGEVRRLLGEAEAMQTQAQRFQQERDQAMMAL 1980

Query: 1218 AELR---------SSISSAVDQRGFEIAELWKQHLAQREADF-------QKTEHELRVQL 1261
             + +         +++    +Q+     E  + HL Q E  +       ++ E ELR +L
Sbjct: 1981 EKCQRDLLLLQEEAAMRGGNEQKLMRELERLRNHLIQMEDTYTQEALQAEEREKELRNRL 2040

Query: 1262 SAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQD----KEEHLRNLQEKYADVI 1317
            S  E        +VQS ++E + +I +++      N+ +D    +   +++  E+Y   +
Sbjct: 2041 SMAEEHAHSSSSAVQSVSKEASAQIDSLQDQLGAMNEQKDHALMQLSMVQSESEEYILSL 2100

Query: 1318 NQIEILRSEIEDEKVA 1333
              ++++  + + EK A
Sbjct: 2101 GNLQMVLEQFQQEKEA 2116


>UniRef50_Q8IBY8 Cluster: Putative uncharacterized protein PF07_0042;
            n=1; Plasmodium falciparum 3D7|Rep: Putative
            uncharacterized protein PF07_0042 - Plasmodium falciparum
            (isolate 3D7)
          Length = 2910

 Score =  132 bits (318), Expect = 1e-28
 Identities = 252/1294 (19%), Positives = 581/1294 (44%), Gaps = 150/1294 (11%)

Query: 317  EIANMTELTKKIEL-LEHLNCQIRQTNKELENKLATMGTESKAVSSPSKK--GSPLISRK 373
            E+  +  + K I++ LE+      Q +K++E +   M  +   +    +K   + +I++ 
Sbjct: 1207 ELEKIKNINKNIQINLENEKKTNEQKDKQIEKQ--KMNIKEMVIQLEKEKIINNEIITQL 1264

Query: 374  SGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDT 433
                  +K+     +  ++ LN + ++     +    EM+IQ   + +++ E +I  ++ 
Sbjct: 1265 ENEKLNNKIIYEDIEKKNK-LNSELEENYENQQKKINEMIIQLEKEKIINNEIIIQLENE 1323

Query: 434  XXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEI 493
                       ++  I ++  E  + +     I+     +  NE  +     K+   ++I
Sbjct: 1324 KGSVKKINTELEN--IKKMNDEMNEKLNKEQKINNDLQLDLENEKNEKDHINKEFEKEKI 1381

Query: 494  KDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDS 553
            K++ +K  +++ K   E    LN EID     + K+  +  L L++ +K ID F+   ++
Sbjct: 1382 KNIQLKKNMDEEKKTNES---LNVEID----RLYKINEHVLLNLEEEKKIIDQFTIDLEN 1434

Query: 554  NKE---IVRL--TEELHHLSQKVAEL-EEEKGNLQLHLVDYDSGRMIESDVYKKMIEMEN 607
             ++   I++L   +E     Q   +L +E + N +L ++ YD G+   +++ +  I++EN
Sbjct: 1435 ERKRNHILQLHFDDEKKKNDQNYEDLLKEREKNKKLQIL-YDDGK---NNISQLNIDLEN 1490

Query: 608  LAETRLKAISLL---ESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQV---CSEIKS 661
               TR   + +L   E +K + + +    ++K +     + +  Q + +Q+     E K+
Sbjct: 1491 -ERTRNNDLKILLDQEKKKNEQINDDLENERKRNNQLQNILNEEQKKKEQLNVSYEEQKN 1549

Query: 662  VH--LEEQIDALSASKKELALVIENLKL-----------DKEQLYGTIKDLENDKEDIMN 708
            ++  LE ++     + K++    E   L           D +Q+  T K ++  K     
Sbjct: 1550 INHQLENELQKQRITYKKMIAKFERKFLMKNTNDTQKIKDTQQIIDTQKIIDTQKIIDTQ 1609

Query: 709  KL---QNYIQENMDLTDKLEKMS-AEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYI 764
            K+    N + +  D    +++M+ AE       ++  E+  ++     I  K  ++ +  
Sbjct: 1610 KIIDTSNNVNQMNDEHKHVDQMNDAESEDNTFLELQLEKVKQVNIDMIIQLKKDKKRIDE 1669

Query: 765  ENIESELSKYKSR--ICRLEESIAVMEDRRYSLERKAD---QLGSYLQEKQKAYSEYTIQ 819
             N+E E  K  +   I ++EE    +E     LE++ +    L   +++  +   +  IQ
Sbjct: 1670 LNLELEKEKEVNDKIIIQMEEYKMKIEHINEELEKEKEINHNLNIRIEKDNEKNEQLNIQ 1729

Query: 820  ---EDELVNRLAVLMDHDRVVEKQL-LEIEHENKELQKKNQILLEENQ-NLQISLSDMQQ 874
               E ++ N++++ +D ++ +  Q  +E++ E K   + N  L EE + N +I++  +++
Sbjct: 1730 LDTEKKMNNQMSIELDEEKKMNHQRRIELDEEKKMNHEMNIELDEEKKINKEINIL-LEE 1788

Query: 875  HYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNT 934
            + N +++  +     +  +     QL D ++N++ +      + ++ +K++ +   + N 
Sbjct: 1789 NKNKIIQINSCLQKEKEINELLNIQLEDKKNNIQELN-----IKLEDEKKLNE---QINV 1840

Query: 935  QIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQ 994
             +E+ I + + LN K E   +   Q+   L+   NNI+ LN+ +E+  KMN ++   ++Q
Sbjct: 1841 TLENKINNIQELNIKLEDEKKLNEQINITLENKINNIQELNIKLEDEKKMNQQI---NIQ 1897

Query: 995  KQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFT 1054
             ++ +         N+I ++N+ LK++ E    +N+++N        ++ + ++ + + T
Sbjct: 1898 LEEEK---------NKIIQINSHLKKEKE----INEELN-------ILLENKKNNIQEIT 1937

Query: 1055 TKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMII 1114
             KL   EE+ +   +Q +  ++  E +  +V E + +     E K   E    + + ++I
Sbjct: 1938 IKL---EEQKKINEEQYIQLEKDKEIINSMVVEMEKEKIINNEIKQKLEKEKKQNDQLVI 1994

Query: 1115 SSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTK 1174
                E  ++   N+             ++V E+E+ I    ++Q +  K N E  +  + 
Sbjct: 1995 HLENEKQANKKLNILLDQNKKINEELNIQV-EQEKLINNEIIVQLK--KENEENNKINSL 2051

Query: 1175 IIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFE 1234
            + +   LN ++T      +E+  +LK +LE    EN NL   +   +  I++ + Q   E
Sbjct: 2052 LEEQNGLNKKVTLQLEKEKEENGKLKLQLENEKQENGNLRFELENEKKDIANLILQLQ-E 2110

Query: 1235 IAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTS 1294
              E  K  + Q + + +KT++ + V++   +   + ++  ++   +   N  + +E+  +
Sbjct: 2111 EKENTKNVMVQMDKEKEKTKN-VMVEMDKEKENTKNVMIELERERENNQNLNIKLEEGKN 2169

Query: 1295 LQN----KLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXX 1350
            + N    +L +K++ +  L  K  +   + E L+ EI++EK                   
Sbjct: 2170 IMNQISIQLVEKQKIINQLNVKLENEKEENEKLKLEIDEEK---------------KYNK 2214

Query: 1351 DLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLE 1410
             +  E +S K+  E+  L I+EE     + S               + E++  E   +L+
Sbjct: 2215 QMSVELESEKEENEKLKLEIDEEKKYNNQMSV--------------ELESE-KEENEKLK 2259

Query: 1411 LKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESE--------LAIL 1462
            L+  E  +  ++ +I L    +E E ++ ++ E +K  + ++ E ESE        L I 
Sbjct: 2260 LEIDEEKKYKNQMSIELENEKEENEKLKLEIDEEKKYNKQMSVELESEKEENEKLKLEID 2319

Query: 1463 RLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEM 1522
              K + N  + E   K+ E E++KL  E++    E  +LNK + E    L+ E  K N++
Sbjct: 2320 EAKKYNNQMNVELESKKEENEKLKL--EID---EEKKNLNKVIYE----LDGEKIKYNDV 2370

Query: 1523 QTALENQEIEIVTLNDEITNLQNMVRASSSKIQK 1556
               L+N++ ++  LN+++ N +  +     K+++
Sbjct: 2371 CIILDNEKNKMKELNEKLINQEKELENIKKKLEE 2404



 Score =  110 bits (265), Expect = 3e-22
 Identities = 219/1128 (19%), Positives = 469/1128 (41%), Gaps = 115/1128 (10%)

Query: 494  KDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDS 553
            K+ N+     +L ++  Q+     E++ +   +     N  L  K+++  + + SK ++ 
Sbjct: 861  KEDNINIPTCQLNNSTCQLNNSTCELNNSTNQLNNFIYNKDLCSKEIEDLLSDMSKYNNI 920

Query: 554  NKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRL 613
            N +  ++  + +  + ++        N+ + L+      ++ +++Y K+  M        
Sbjct: 921  NVD--KIMHKYNTYNDEILLKMSNMKNVDMLLL------LLSNNIYNKI--MSTTLYNNF 970

Query: 614  KAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSA 673
              I  +    F  V ++ +       + +    I++   D   ++ K  H++  I+  + 
Sbjct: 971  DIIKFIMKWIFVHVIKIFVKDTYMLYINNNQGKINESNEDHNLNKNKDSHIDNNIEGENF 1030

Query: 674  SKKELALVIENLKLDKEQLYGTIK-DLENDKEDIMNKLQNYIQ--ENMDLTDKLEKMSAE 730
               +  L+ E +    E+    IK +LEN+K  I+N ++  +Q  E +   D    +  E
Sbjct: 1031 LMNQ-KLIDEEV----EKRVNIIKVELENEKNIIINNIKEELQNEEKIKYNDIKTNLERE 1085

Query: 731  KISELLAKINHEEQSKIQTQFGI--DAKIQERDLYIENIESELSKYKSRICRLEESIAVM 788
            K   +   I  E++ KI  +  I  + K +  D   + +E+E  + K     L+    + 
Sbjct: 1086 KKINMHMNIELEKERKINDEMMIKFEKKNKMYDDINKELENEKKQNKEIYMELQNIKNIN 1145

Query: 789  EDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHEN 848
             D  ++LE K+ Q      + +K    Y     EL N+  +    +  + K+ +  +   
Sbjct: 1146 SDMNFALEDKSVQYDQKCIDFEKLNKMYEDTCKELNNKNVLYEQMNTQLYKEKINNDEIC 1205

Query: 849  KELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLK 908
             EL+K   I    N+N+QI+L + ++  N   +K         +    Q +   + +N  
Sbjct: 1206 TELEKIKNI----NKNIQINLEN-EKKTNEQKDKQIEKQKMNIKEMVIQLEKEKIINN-- 1258

Query: 909  RITHEHQTLIVQKKKEIEDLE--IEFNTQIESAIRD-KKVLNE---KYEKNIEYVTQLEA 962
             I  + +   +  K   ED+E   + N+++E    + +K +NE   + EK      ++  
Sbjct: 1259 EIITQLENEKLNNKIIYEDIEKKNKLNSELEENYENQQKKINEMIIQLEKEKIINNEIII 1318

Query: 963  QLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKD 1022
            QL+  K +++ +N  +E + KMN E+ +K + K+Q  + D      NE N+ + + K+ +
Sbjct: 1319 QLENEKGSVKKINTELENIKKMNDEMNEK-LNKEQKINNDLQLDLENEKNEKDHINKEFE 1377

Query: 1023 EE---IIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNE 1079
            +E    I L + ++  + +  S+  + +         L N+EEE + + +  +D +   +
Sbjct: 1378 KEKIKNIQLKKNMDEEKKTNESLNVEIDRLYKINEHVLLNLEEEKKIIDQFTIDLENERK 1437

Query: 1080 ELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXX 1139
               IL    DD   E K+    +E  + + E    +  ++ + DD  N            
Sbjct: 1438 RNHILQLHFDD---EKKKNDQNYEDLLKEREK---NKKLQILYDDGKN--------NISQ 1483

Query: 1140 XXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQL 1199
              + ++ E     +  +L +Q  K N ++ +    +      N +L   +++N+EQ    
Sbjct: 1484 LNIDLENERTRNNDLKILLDQEKKKNEQIND---DLENERKRNNQL--QNILNEEQ---- 1534

Query: 1200 KSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRV 1259
              K EQLN   +   +   +L + +          IA+  ++ L +   D QK +     
Sbjct: 1535 -KKKEQLNVSYEEQKNINHQLENELQKQRITYKKMIAKFERKFLMKNTNDTQKIKDT--- 1590

Query: 1260 QLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKL-QDKEEHLRNLQEKYADVIN 1318
                     +Q++D+ +     +T KI+  +++    N + Q  +EH      K+ D +N
Sbjct: 1591 ---------QQIIDTQKII---DTQKIIDTQKIIDTSNNVNQMNDEH------KHVDQMN 1632

Query: 1319 QIEILRS---EIEDEKVAFXXXXXXXXXXXXXXXXD-LRTENQSYKQMQEQSILNINEEN 1374
              E   +   E++ EKV                  D L  E +  K++ ++ I+ + E  
Sbjct: 1633 DAESEDNTFLELQLEKVKQVNIDMIIQLKKDKKRIDELNLELEKEKEVNDKIIIQMEEYK 1692

Query: 1375 AQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEF 1434
             +++  +             +N    K  E   QL ++     +  ++ +I L +     
Sbjct: 1693 MKIEHIN-EELEKEKEINHNLNIRIEKDNEKNEQLNIQLDTEKKMNNQMSIELDEEKKMN 1751

Query: 1435 ENVRQQLVEYEKRIEDLTYEKESELAI---LRLKMHENANHY----ETMQKESEI----- 1482
               R +L E +K   ++  E + E  I   + + + EN N        +QKE EI     
Sbjct: 1752 HQRRIELDEEKKMNHEMNIELDEEKKINKEINILLEENKNKIIQINSCLQKEKEINELLN 1811

Query: 1483 ----ERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALE-----NQEIEI 1533
                ++   I+ELN+K+ +   LN+Q+   N  LE ++    E+   LE     N++I I
Sbjct: 1812 IQLEDKKNNIQELNIKLEDEKKLNEQI---NVTLENKINNIQELNIKLEDEKKLNEQINI 1868

Query: 1534 VTLNDEITNLQ--NMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKE 1579
             TL ++I N+Q  N+      K+ + ++   + ++ +  Q+++ + KE
Sbjct: 1869 -TLENKINNIQELNIKLEDEKKMNQQINIQLEEEKNKIIQINSHLKKE 1915



 Score = 55.6 bits (128), Expect = 1e-05
 Identities = 131/731 (17%), Positives = 308/731 (42%), Gaps = 53/731 (7%)

Query: 306  EKTEIEEKGSLEIANMTELTKKIEL-LEHLNCQIRQTNKELENKLATMGTESKAVSSPSK 364
            EK +I  + ++++ N  E  +K++L ++      +Q + ELE++          +    K
Sbjct: 2180 EKQKIINQLNVKLENEKEENEKLKLEIDEEKKYNKQMSVELESEKEENEKLKLEIDEEKK 2239

Query: 365  KGSPL---ISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDL 421
              + +   +  +   N   K++    +     ++ + + +  +NE  KLE+  +      
Sbjct: 2240 YNNQMSVELESEKEENEKLKLEIDEEKKYKNQMSIELENEKEENEKLKLEIDEEKKYNKQ 2299

Query: 422  VDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKV 481
            +  E    +++            K      ++LE ++       + +    +++N++   
Sbjct: 2300 MSVELESEKEENEKLKLEIDEAKKYNNQMNVELESKKEENEKLKLEIDEEKKNLNKVIYE 2359

Query: 482  QEQLKQELND-----EIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKS-NHKL 535
             +  K + ND     + +   +K+L EKL + E+++  +  +++    N  K +  N+K 
Sbjct: 2360 LDGEKIKYNDVCIILDNEKNKMKELNEKLINQEKELENIKKKLEEETLNFKKYREINYKE 2419

Query: 536  KLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIE 595
            K      T++N   V   NK    +  E++ L       + +K   + +  D D   M +
Sbjct: 2420 KNGSNDYTMENGKNVVTRNK----INNEMNILDILDKNKKTKKTISKSNNNDNDDNNM-K 2474

Query: 596  SDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQ--LQSD 653
             + Y K+    +  E  +K   L    +F+  +++     K D  + K+   ++      
Sbjct: 2475 DEKYNKLYY--SYVEIVIKKEEL--ENEFN--EQMKYFNDKVDIFDKKVQYFNKKITHYK 2528

Query: 654  QVCSEIKSVHLEEQIDALSASKKELALVIENLKL-DKEQLYGTIKDLENDKEDIMNKLQN 712
             VC+    +    +I       +E+   IE + + DK  L G I +++   ++I   +  
Sbjct: 2529 NVCNMY--IKNNGKISTCIKKLEEILYSIEKVHIKDKIILDGKIYNIKIIIKEINECIHM 2586

Query: 713  YIQENMDLTDKL--EKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQE--RDLYIENIE 768
             IQE  D TD L  +++  EK + LL KI + E+ K       D+++++  ++L  +NI 
Sbjct: 2587 KIQETED-TDVLLYDEVINEK-NILLEKILNNEKDKNIYHIEKDSELEKYMKELNFKNIN 2644

Query: 769  SELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSY------LQEKQKAYSEYTIQEDE 822
               + + S    L+E   + +  + ++E  A ++  Y      L ++ +   +     ++
Sbjct: 2645 DLFTFHLSM---LDELCIIKKCYQQAVEENAMKIKEYDNNILILNKQIELKEKKNYINEK 2701

Query: 823  LVNRLAVLMDHDRVVEKQLLE-IEHENKELQKKNQILLEENQ----NLQI-SLSDMQQHY 876
                L + +D+ + +   LL  ++H++ +  K+ + +  +N+    N++I ++ + +Q+ 
Sbjct: 2702 NCKSLLLEVDNLKFILNDLLSYVDHKDGKRNKRQRKMSIKNELKYINMEIKNIENEEQNM 2761

Query: 877  --NALVEK-ANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFN 933
              N+ +E   N  ++  +    ++    +    +   ++ H+ +  +K  E+ D   + N
Sbjct: 2762 LINSEIENDGNHNEVPCAVINVHENIRNNHNRKMDNNSNIHENIETKKTLELHDSIEKMN 2821

Query: 934  TQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHV 993
            T  E++      LNE  E N+  V  L     EYK N    +  ++  N   L+++   +
Sbjct: 2822 T-FENSFERNNTLNE--ENNLRNVQSLYPNFLEYKENSSFKSSTLKSNNLSELDILSNEL 2878

Query: 994  QKQQTQSPDYT 1004
                T    Y+
Sbjct: 2879 NSNTTSKRKYS 2889


>UniRef50_Q7RGY2 Cluster: Repeat organellar protein-related; n=3;
            Plasmodium (Vinckeia)|Rep: Repeat organellar
            protein-related - Plasmodium yoelii yoelii
          Length = 1441

 Score =  132 bits (318), Expect = 1e-28
 Identities = 272/1398 (19%), Positives = 605/1398 (43%), Gaps = 118/1398 (8%)

Query: 213  DTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHS 272
            D   Q+ +   NF   E E +D+ +  LK I +  +++   E  NK+ E    E+ LE  
Sbjct: 7    DDDDQVRETGHNF--KEYELEDQLKETLKSITALSIKVKEYE--NKIEELEN-ELKLEKE 61

Query: 273  K-LAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTK-KIEL 330
            K + +E E+              L K+       ++ +I  K  + +    +L   + E 
Sbjct: 62   KQINKEYEKELNEKCEFIKREMELLKEKELNINIKENKINNKEIITLKKEEKLNDIENEY 121

Query: 331  LEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRK--SGRNTASKMKSPWSQ 388
            +E  N +  + N E+ N   ++   S  +    K+    I++K     N   ++K    +
Sbjct: 122  IEK-NKEKEKLNYEITNIKMSLDKLSCEIQE-KKENLEKINKKVVEKENNLRELKEFMKE 179

Query: 389  LSS--ETLNQDTDKKINKNEIAKLEMVIQSLNK--DLVDKEYVISEKDTXXXXXXXXXXG 444
             +   E+LN+  D K  KN   KLE   +   K  +++D + +  EK             
Sbjct: 180  KNEIIESLNKTIDDK--KNAYEKLETNFEEKRKMIEMLDSKLIEKEKKFEIKKEKLEKEN 237

Query: 445  KDTLIAQLQLEH-QQHMEGPSLIHVGTNTEDVN---EIAKVQEQL-KQELNDEIKDVNVK 499
            +  +     +E+ ++H +           + +N   E+ K++  L K     EI  + +K
Sbjct: 238  EVIMEKLKDIENKEEHFKNKEEKFKNKEEKFINLENELNKLKSDLSKNACQMEIYKMEIK 297

Query: 500  DLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDS--NKEI 557
            DL + L   E +I ++ +E D    NM      +KL         DN  K S+   NK+I
Sbjct: 298  DLSQSLVEKEREIFEIKNEYDDKINNM-----KNKLSNFNNDDNDDNTVKCSEEIINKKI 352

Query: 558  VRLTEELHHLSQKVAELEE--EKGNLQLHLVDYDSG---RMIESDVYKKMIEMENLAETR 612
                 +L  + +K  EL E  +K NL++  +  +     + +E +  K  IE+ +L    
Sbjct: 353  EEAVNKL--IKEKEMELNEIHKKYNLEIEKIKNEINEKEKELEQNKKKHNIEINDLT--- 407

Query: 613  LKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALS 672
             K I + E +  D+ +E  I   K D  ++ +    +++++++ +E+ S  L  ++++L+
Sbjct: 408  -KEIQIREKKIEDVKEEYKIELSKLDSEKNNI----KIENNELNNEVNS--LNNEVNSLN 460

Query: 673  ASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEK---MSA 729
                 L   I +L  DK+ L    K L     D++N L+N I  + +  +K+++   M  
Sbjct: 461  NEVNSLNNEINSLNNDKQTLSKNNKLLN----DLINNLKNEINNSDNKMNKMKEDIIMLN 516

Query: 730  EKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVME 789
            E++      I+  E+      F  + K++E++ Y +++  E++  ++ I   E+    M+
Sbjct: 517  EELEGKCVVIDEIEKKYKNEIFIFEKKLKEKENY-DDLNDEINILRNDISVKEKEFIEMK 575

Query: 790  DRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENK 849
            +     E K +      +EK K Y      E+EL N L +  ++++ + KQ+ E+  +  
Sbjct: 576  E---FYENKINLYNKNFEEKTKYY------ENEL-NILRLKYNNEQDLIKQIDELNIQKL 625

Query: 850  ELQKKNQILLEENQNLQISL-SDMQQHYNALVEKANRTDLAESESTKYQTQLR---DLES 905
            + ++K   L ++N  +  S+ + +   Y+  ++ ++  +  E+   K++ + R   + ES
Sbjct: 626  KTEEKYLQLYDDNIKMFKSICAKINTTYSENIKGSDLVNFVEAY-IKHRDESRFDANSES 684

Query: 906  NLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKK--VLNEKYEKNIEYVTQLEAQ 963
             +K +  E   L  + ++E+  +  E   ++     + K  V+    E   E V   E  
Sbjct: 685  GIKEVVAE---LEEKHREEVSRIREEHKKEVVRIGEEHKEEVVRIGEEHKEEVVKIGEQH 741

Query: 964  LQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDE 1023
             +E     E     V ++ + + E + +  ++ + +     E++  E+    A L+    
Sbjct: 742  REELGEKEEEHKKEVAKIGEQHKEEMVRIREEHKKEVSRIREEHKKEM----AELEDGRT 797

Query: 1024 EIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQI 1083
            +++A+ ++ +  +V  + +  +++ +++    K+E  EE  + VS+     ++H +E+  
Sbjct: 798  DVVAVLEEEHKKEV--VRIGEEHKKEVS----KIE--EEHKKEVSRI---REEHKKEMSE 846

Query: 1084 LVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNV---DXXXXXXXXXXX 1140
            L ++  D + EL+E      + I +     +S   E    + + +               
Sbjct: 847  LEKKHADVVAELEEQHKEEVVKIGEEHREEVSKIEEEHKKEVSRIREEHKKEVNMLEKRH 906

Query: 1141 XLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKII-QLETLNTELTGH-DVVNQEQINQ 1198
               + E EE  +E S L++ SA + TEL+E + + + ++   + E  G  +  ++E++++
Sbjct: 907  AAVMTELEEHKKEMSELEKNSADVVTELEEKHREELGKMGEQHIEEMGKIEEKHREEVSR 966

Query: 1199 L----KSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTE 1254
            +    K ++ +L  ++ +++  + E      + +++R  ++  + ++    RE +  K  
Sbjct: 967  IEEQHKEEVAELEKKHTDVVVMLEEQHKEEVNVLEKRHADVVVVLEEK--HRE-EVSKMG 1023

Query: 1255 HELRVQLSAFESKYEQLLDSVQSSTQEETNKIVT--MEQVTSLQNKLQDKEEHLRNLQEK 1312
             + + +++  E     LLD ++ + + E +++     E    L   L  K E ++N   K
Sbjct: 1024 EQHKEEVAELEKNNASLLDVIEENHKSEVSRLKEEHKESTRELVETLSQKNEEIQNSNNK 1083

Query: 1313 YADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINE 1372
              ++ N I+    ++ D  + +                +++  N+   +M+++S   I +
Sbjct: 1084 IEELTNVIK----DLNDSIMCYKKKISEDVEKRNEYNEEIQKLNKRLNEMKDKSDKEIIK 1139

Query: 1373 ENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLEL-KDSEIYQKTHEYTITLTQRN 1431
            +  ++KK +                  +K+L   ++ E+  D+   +K  E  I    +N
Sbjct: 1140 KEDEIKKLNKKISNYKIFEIKENTYKNSKMLINENKEEIIVDNICKEKISESDIEGKGKN 1199

Query: 1432 DEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEEL 1491
             +   +   L + E+ +  ++  K     ++ +  +   N  E  +KE + +  K +E+L
Sbjct: 1200 LK---MILSLKKKERSVFSVSDNKNENNELVDIVRNTYINKIEVYKKEIK-DNNKNMEDL 1255

Query: 1492 NVKITESVSLNKQVAELNKALEEE---VAKTNEMQTALENQEIEIVTLNDEITNLQNMVR 1548
              KI +  +    +  +   L EE   + K  EM+    N+  EI+ LND+I  L   + 
Sbjct: 1256 KNKIIDLSNELANLKNVKNVLTEENDNLRKEMEMKQNKVNENDEILNLNDDIIKLTKEI- 1314

Query: 1549 ASSSKIQKHVSFASDTKQ 1566
              S   +K++   +D +Q
Sbjct: 1315 --SEWKEKNIKLENDIEQ 1330



 Score =  125 bits (301), Expect = 1e-26
 Identities = 230/1234 (18%), Positives = 529/1234 (42%), Gaps = 101/1234 (8%)

Query: 424  KEYVISE--KDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNE---- 477
            KEY + +  K+T           K+      +LE++  +E    I+     E +NE    
Sbjct: 20   KEYELEDQLKETLKSITALSIKVKEYENKIEELENELKLEKEKQINKEYEKE-LNEKCEF 78

Query: 478  IAKVQEQLKQ-ELNDEIKD--VNVKDLI-----EKLKSAEEQITQLNDEIDAANKNMIKV 529
            I +  E LK+ ELN  IK+  +N K++I     EKL   E +  + N E +  N  +  +
Sbjct: 79   IKREMELLKEKELNINIKENKINNKEIITLKKEEKLNDIENEYIEKNKEKEKLNYEITNI 138

Query: 530  KSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYD 589
            K +      ++Q+  +N  K+   NK++V     L  L + + E  E   +L   + D  
Sbjct: 139  KMSLDKLSCEIQEKKENLEKI---NKKVVEKENNLRELKEFMKEKNEIIESLNKTIDDKK 195

Query: 590  SG-RMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADIS 648
            +    +E++  +K   +E L    ++     E +K  L +E  ++ +K  ++E+K     
Sbjct: 196  NAYEKLETNFEEKRKMIEMLDSKLIEKEKKFEIKKEKLEKENEVIMEKLKDIENKEEHFK 255

Query: 649  QLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGT-------IKDLEN 701
              +      E K ++LE +++ L +   + A  +E  K++ + L  +       I +++N
Sbjct: 256  NKEEKFKNKEEKFINLENELNKLKSDLSKNACQMEIYKMEIKDLSQSLVEKEREIFEIKN 315

Query: 702  DKEDIMNKLQNYIQE--NMDLTDKLEKMSAE----KISELLAKINHEEQ---SKIQTQFG 752
            + +D +N ++N +    N D  D   K S E    KI E + K+  E++   ++I  ++ 
Sbjct: 316  EYDDKINNMKNKLSNFNNDDNDDNTVKCSEEIINKKIEEAVNKLIKEKEMELNEIHKKYN 375

Query: 753  IDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKA 812
            ++ +  + ++  +  E E +K K  I  + +    ++ R   +E   ++    L +    
Sbjct: 376  LEIEKIKNEINEKEKELEQNKKKHNI-EINDLTKEIQIREKKIEDVKEEYKIELSKLDSE 434

Query: 813  YSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDM 872
             +   I+ +EL N +  L +    +  ++  + +E   L    Q L + N+ L   ++++
Sbjct: 435  KNNIKIENNELNNEVNSLNNEVNSLNNEVNSLNNEINSLNNDKQTLSKNNKLLNDLINNL 494

Query: 873  QQHYNALVEKANRTD----LAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDL 928
            +   N    K N+      +   E       + ++E   K      +  + ++K+  +DL
Sbjct: 495  KNEINNSDNKMNKMKEDIIMLNEELEGKCVVIDEIEKKYKNEIFIFEKKL-KEKENYDDL 553

Query: 929  EIEFNT-QIESAIRDKKVLNEK--YEKNIE-YVTQLEAQLQEYKNNIENLNMNVEELNKM 984
              E N  + + ++++K+ +  K  YE  I  Y    E + + Y+N +  L +       +
Sbjct: 554  NDEINILRNDISVKEKEFIEMKEFYENKINLYNKNFEEKTKYYENELNILRLKYNNEQDL 613

Query: 985  NLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKD---EEIIALNQKIN--NAQVSY 1039
              ++ + ++QK +T+   Y + Y + I    ++  + +    E I  +  +N   A + +
Sbjct: 614  IKQIDELNIQKLKTEEK-YLQLYDDNIKMFKSICAKINTTYSENIKGSDLVNFVEAYIKH 672

Query: 1040 MS---MVSDYESKLAQFTTKLENME-EEMQRVSKQLLDSKQHNEELQILVREQDDQIKEL 1095
                   ++ ES + +   +LE    EE+ R+ ++      H +E+  +  E  +++  +
Sbjct: 673  RDESRFDANSESGIKEVVAELEEKHREEVSRIREE------HKKEVVRIGEEHKEEVVRI 726

Query: 1096 KETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERS 1155
             E      + I +     +        ++ +  +            ++++EE +  +E S
Sbjct: 727  GEEHKEEVVKIGEQHREELGE-----KEEEHKKEVAKIGEQHKEEMVRIREEHK--KEVS 779

Query: 1156 VLQEQSAKLNTELQECYTKIIQL--ETLNTELTGHDVVNQEQINQL----KSKLEQLNTE 1209
             ++E+  K   EL++  T ++ +  E    E+      ++++++++    K ++ ++  E
Sbjct: 780  RIREEHKKEMAELEDGRTDVVAVLEEEHKKEVVRIGEEHKKEVSKIEEEHKKEVSRIREE 839

Query: 1210 NDNLLSTVAELRSSISSAVDQRGFE----IAELWKQHLAQREADFQKTEHELRVQLSAFE 1265
            +   +S + +  + + + ++++  E    I E  ++ +++ E + +K    +R +     
Sbjct: 840  HKKEMSELEKKHADVVAELEEQHKEEVVKIGEEHREEVSKIEEEHKKEVSRIREEHKKEV 899

Query: 1266 SKYEQLLDSVQSSTQEETNKIVTMEQVTS-LQNKLQDKE-EHLRNLQEKYADVINQIEIL 1323
            +  E+   +V +  +E   ++  +E+ ++ +  +L++K  E L  + E++ + + +IE  
Sbjct: 900  NMLEKRHAAVMTELEEHKKEMSELEKNSADVVTELEEKHREELGKMGEQHIEEMGKIEEK 959

Query: 1324 RSE----IEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKK 1379
              E    IE++                    +   E  +  + +   ++ + EE  + + 
Sbjct: 960  HREEVSRIEEQHKEEVAELEKKHTDVVVMLEEQHKEEVNVLEKRHADVVVVLEEKHREEV 1019

Query: 1380 SSXXXXXXXXXXXXRVNDAEA-KVLELTHQLELK--DSEIYQKTHEYTITLTQRNDEFEN 1436
            S               N+A    V+E  H+ E+     E  + T E   TL+Q+N+E +N
Sbjct: 1020 SKMGEQHKEEVAELEKNNASLLDVIEENHKSEVSRLKEEHKESTRELVETLSQKNEEIQN 1079

Query: 1437 VRQQLVEYEKRIEDLT-----YEKE-SELAILRLKMHENA----NHYETMQKESEIERVK 1486
               ++ E    I+DL      Y+K+ SE    R + +E           M+ +S+ E +K
Sbjct: 1080 SNNKIEELTNVIKDLNDSIMCYKKKISEDVEKRNEYNEEIQKLNKRLNEMKDKSDKEIIK 1139

Query: 1487 LIEELNVKITESVSLNK--QVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQ 1544
              +E+  K+ + +S  K  ++ E      + +   N+ +  ++N   E ++ +D     +
Sbjct: 1140 KEDEIK-KLNKKISNYKIFEIKENTYKNSKMLINENKEEIIVDNICKEKISESDIEGKGK 1198

Query: 1545 NM-VRASSSKIQKHVSFASDTKQGRDEQLDNTMN 1577
            N+ +  S  K ++ V   SD K   +E +D   N
Sbjct: 1199 NLKMILSLKKKERSVFSVSDNKNENNELVDIVRN 1232



 Score =  115 bits (276), Expect = 1e-23
 Identities = 287/1493 (19%), Positives = 630/1493 (42%), Gaps = 152/1493 (10%)

Query: 90   ISESLANTLKQKEILMEKIKQYK-ELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLS 148
            + + L  TLK    L  K+K+Y+ ++ +  +   +                +   +    
Sbjct: 24   LEDQLKETLKSITALSIKVKEYENKIEELENELKLEKEKQINKEYEKELNEKCEFIKREM 83

Query: 149  NTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNK---ATTXXXXXXXXXXX 205
              +KEK+  +++ + K+   E   L  +EK+N+ +     KNK                 
Sbjct: 84   ELLKEKELNINIKENKINNKEIITLKKEEKLNDIENEYIEKNKEKEKLNYEITNIKMSLD 143

Query: 206  XXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKD---IESKDVRISSLEEANKLLEA 262
                  ++ K+ + K+ +  +  E   ++ K+ + +    IES +  I   + A + LE 
Sbjct: 144  KLSCEIQEKKENLEKINKKVVEKENNLRELKEFMKEKNEIIESLNKTIDDKKNAYEKLE- 202

Query: 263  ARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMT 322
              FE   E  K+ + L+                 ++  E   E+  +IE K      N  
Sbjct: 203  TNFE---EKRKMIEMLDSKLIEKEKKFEIKKEKLEKENEVIMEKLKDIENKEE-HFKNKE 258

Query: 323  ELTK-KIELLEHLNCQIRQTNKELENKLATM---GTESKAVS-SPSKKGSPLISRKSG-R 376
            E  K K E   +L  ++ +   +L      M     E K +S S  +K   +   K+   
Sbjct: 259  EKFKNKEEKFINLENELNKLKSDLSKNACQMEIYKMEIKDLSQSLVEKEREIFEIKNEYD 318

Query: 377  NTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISE----KD 432
            +  + MK+  S  +++  N D   K ++  I K   + +++NK + +KE  ++E     +
Sbjct: 319  DKINNMKNKLSNFNNDD-NDDNTVKCSEEIINK--KIEEAVNKLIKEKEMELNEIHKKYN 375

Query: 433  TXXXXXXXXXXGKDTLIAQLQLEHQQHMEG-PSLIHV-GTNTEDVNEIAKVQ-EQLKQEL 489
                        K+  + Q + +H   +      I +     EDV E  K++  +L  E 
Sbjct: 376  LEIEKIKNEINEKEKELEQNKKKHNIEINDLTKEIQIREKKIEDVKEEYKIELSKLDSEK 435

Query: 490  ND---EIKDVN--VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKL---KLKQMQ 541
            N+   E  ++N  V  L  ++ S   ++  LN+EI++ N +   +  N+KL    +  ++
Sbjct: 436  NNIKIENNELNNEVNSLNNEVNSLNNEVNSLNNEINSLNNDKQTLSKNNKLLNDLINNLK 495

Query: 542  KTIDNF-SKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYK 600
              I+N  +K++   ++I+ L EEL      + E+E++  N ++ + +    ++ E + Y 
Sbjct: 496  NEINNSDNKMNKMKEDIIMLNEELEGKCVVIDEIEKKYKN-EIFIFE---KKLKEKENYD 551

Query: 601  KMIEMENLA--ETRLKAISLLESQKFDLVQELHILQQKYDE----VEDKLADISQLQSDQ 654
             + +  N+   +  +K    +E ++F    ++++  + ++E     E++L +I +L+ + 
Sbjct: 552  DLNDEINILRNDISVKEKEFIEMKEF-YENKINLYNKNFEEKTKYYENEL-NILRLKYNN 609

Query: 655  VCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDL--ENDK-EDIMNKLQ 711
                IK +  E  I  L   +K L L  +N+K+ K  +   I     EN K  D++N ++
Sbjct: 610  EQDLIKQID-ELNIQKLKTEEKYLQLYDDNIKMFK-SICAKINTTYSENIKGSDLVNFVE 667

Query: 712  NYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESEL 771
             YI+   +   + +  S   I E++A++  + + ++       ++I+E   + + +    
Sbjct: 668  AYIKHRDE--SRFDANSESGIKEVVAELEEKHREEV-------SRIREE--HKKEVVRIG 716

Query: 772  SKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLM 831
             ++K  + R+ E     E+     E+  ++LG   +E +K  ++   Q  E + R  +  
Sbjct: 717  EEHKEEVVRIGEE--HKEEVVKIGEQHREELGEKEEEHKKEVAKIGEQHKEEMVR--IRE 772

Query: 832  DHDRVVEKQLLEIEHENKELQKKN----QILLEENQNLQISLSDMQQHYNALVEKANRTD 887
            +H + V +   E + E  EL+        +L EE++   + + +  +   + +E+ ++ +
Sbjct: 773  EHKKEVSRIREEHKKEMAELEDGRTDVVAVLEEEHKKEVVRIGEEHKKEVSKIEEEHKKE 832

Query: 888  LAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRD-KKVL 946
            ++     +++ ++ +LE     +  E   L  Q K+E+  +  E   ++     + KK +
Sbjct: 833  VSRIRE-EHKKEMSELEKKHADVVAE---LEEQHKEEVVKIGEEHREEVSKIEEEHKKEV 888

Query: 947  NEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQ 1006
            +   E++ + V  LE +       +E     + EL K + +++ +  +K + +     EQ
Sbjct: 889  SRIREEHKKEVNMLEKRHAAVMTELEEHKKEMSELEKNSADVVTELEEKHREELGKMGEQ 948

Query: 1007 YINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQR 1066
            +I E+ K    +++K  E      +++  +  +   V++ E K       LE        
Sbjct: 949  HIEEMGK----IEEKHRE------EVSRIEEQHKEEVAELEKKHTDVVVMLE-------- 990

Query: 1067 VSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDAN 1126
                    +QH EE+ +L +   D +  L+E        + K          E   ++A+
Sbjct: 991  --------EQHKEEVNVLEKRHADVVVVLEE---KHREEVSKMGEQHKEEVAELEKNNAS 1039

Query: 1127 NVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELT 1186
             +D            LK +E +E  +E   L E  ++ N E+Q    KI +L  +  +L 
Sbjct: 1040 LLDVIEENHKSEVSRLK-EEHKESTRE---LVETLSQKNEEIQNSNNKIEELTNVIKDLN 1095

Query: 1187 GHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQR 1246
               +  +++I++   K  + N E   L   + E++      + ++  EI +L K+    +
Sbjct: 1096 DSIMCYKKKISEDVEKRNEYNEEIQKLNKRLNEMKDKSDKEIIKKEDEIKKLNKKISNYK 1155

Query: 1247 EADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHL 1306
              + ++  ++   ++   E+K E ++D++      E++ I    +   +   L+ KE  +
Sbjct: 1156 IFEIKENTYK-NSKMLINENKEEIIVDNICKEKISESD-IEGKGKNLKMILSLKKKERSV 1213

Query: 1307 RNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQS 1366
             ++ +   +    ++I+R+   ++   +                +++  N++ + ++ + 
Sbjct: 1214 FSVSDNKNENNELVDIVRNTYINKIEVY--------------KKEIKDNNKNMEDLKNK- 1258

Query: 1367 ILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTIT 1426
            I++++ E A LK                +   + KV E    L L D +I + T E +  
Sbjct: 1259 IIDLSNELANLKNVKNVLTEENDNLRKEMEMKQNKVNENDEILNLND-DIIKLTKEIS-E 1316

Query: 1427 LTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVK 1486
              ++N + EN  +Q +  E +I      KE  L I   K++E+ N    ++ + EIE+ K
Sbjct: 1317 WKEKNIKLENDIEQ-INKEYKI------KEENLMI---KINESINEVNNLKNQIEIEKKK 1366

Query: 1487 LIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDE 1539
              E LN   T +V+        NK +E  + +   ++    N+EIE  T ND+
Sbjct: 1367 K-ENLN---TSNVN--------NKIVENNILENGNLKQNNSNKEIEDKTGNDD 1407



 Score = 68.1 bits (159), Expect = 2e-09
 Identities = 87/490 (17%), Positives = 210/490 (42%), Gaps = 42/490 (8%)

Query: 1084 LVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLK 1143
            ++ + DDQ++E       +E+     E      T++ ++  +  V             LK
Sbjct: 4    IIYDDDDQVRETGHNFKEYELEDQLKE------TLKSITALSIKVKEYENKIEELENELK 57

Query: 1144 VQEEEEFIQE-RSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVN---QEQINQL 1199
            +++E++  +E    L E+   +  E++    K + +     ++   +++    +E++N +
Sbjct: 58   LEKEKQINKEYEKELNEKCEFIKREMELLKEKELNINIKENKINNKEIITLKKEEKLNDI 117

Query: 1200 KSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRV 1259
            +++  + N E + L   +  ++ S+    D+   EI E  K++L +      + E+ LR 
Sbjct: 118  ENEYIEKNKEKEKLNYEITNIKMSL----DKLSCEIQEK-KENLEKINKKVVEKENNLR- 171

Query: 1260 QLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQ 1319
            +L  F  +  ++++S+  +  ++ N          L+   ++K + +  L  K  +   +
Sbjct: 172  ELKEFMKEKNEIIESLNKTIDDKKNAY------EKLETNFEEKRKMIEMLDSKLIEKEKK 225

Query: 1320 IEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKK 1379
             EI + ++E E                      + + + +K  +E+  +N+  E  +LK 
Sbjct: 226  FEIKKEKLEKENEVIMEKLKDIENKEEH----FKNKEEKFKN-KEEKFINLENELNKLKS 280

Query: 1380 SSXXXXXXXXXXXXRVNDAEAKVLELTHQL-ELK---DSEIYQKTHEYTITLTQRNDEFE 1435
                           + D    ++E   ++ E+K   D +I    ++ +      ND+  
Sbjct: 281  DLSKNACQMEIYKMEIKDLSQSLVEKEREIFEIKNEYDDKINNMKNKLSNFNNDDNDDNT 340

Query: 1436 -NVRQQLV--EYEKRIEDLTYEKESELAILR----LKMHENANHYETMQKESEIERVKLI 1488
                ++++  + E+ +  L  EKE EL  +     L++ +  N     +KE E  + K  
Sbjct: 341  VKCSEEIINKKIEEAVNKLIKEKEMELNEIHKKYNLEIEKIKNEINEKEKELEQNKKKHN 400

Query: 1489 EELNVKITESVSLNKQVAELNKALEEEVAK--TNEMQTALENQEI--EIVTLNDEITNLQ 1544
             E+N    E     K++ ++ +  + E++K  + +    +EN E+  E+ +LN+E+ +L 
Sbjct: 401  IEINDLTKEIQIREKKIEDVKEEYKIELSKLDSEKNNIKIENNELNNEVNSLNNEVNSLN 460

Query: 1545 NMVRASSSKI 1554
            N V + +++I
Sbjct: 461  NEVNSLNNEI 470


>UniRef50_Q54NP8 Cluster: Kinesin 4; n=3; Dictyostelium
            discoideum|Rep: Kinesin 4 - Dictyostelium discoideum AX4
          Length = 1922

 Score =  132 bits (318), Expect = 1e-28
 Identities = 267/1392 (19%), Positives = 564/1392 (40%), Gaps = 144/1392 (10%)

Query: 244  ESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPS 303
            E  D+    LEE  KL+E     + L +++L ++  +                 +  E  
Sbjct: 568  EDLDLIYEELEENKKLIEEYESTLELLNNQLDEKEIEHKELLIIIDQWEQECTNR--ENQ 625

Query: 304  CEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKEL---ENKLATMGTESKAVS 360
             +E  EI+++    I  + +  K +E  +     I Q N +L   E++ +      + V 
Sbjct: 626  NQELLEIDQQSKQSIQQLND--KLLETKQQSKQSIDQLNLQLIDIESESSKNKKSFENVL 683

Query: 361  SPSKKGSPLISRKSGRNTASKMKSPWS--QLSSETLNQDTDKKINKNEIAKLEMVIQSLN 418
               +K   L  R   +    +++S      L++  L  +T  +   N   + +  IQSLN
Sbjct: 684  GVFEKSYRLAERLEDKYFTKEIESKKQIETLANSYLQLETTYQQQLNINQQSQQKIQSLN 743

Query: 419  KDLVDKEYV-ISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNE 477
             D+   + V +  KD            K  +I   +LE + +    +LI +    E  N 
Sbjct: 744  NDIEQFKLVWVPLKDQVNGYFQENQMFKQYII---ELEEKYN----TLIDLQKEVEQ-NY 795

Query: 478  IAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKL 537
            +      L+Q+ ND+ + + +  L  +  +  +Q+   N ++     N++   +     L
Sbjct: 796  LTNT---LEQQRNDQYQ-IEINQLTTEYNNQIQQLESTNQKLQTQLYNLLANATQSTQTL 851

Query: 538  KQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESD 597
            +Q  +T         S +EI  LT E+  L  +   +  +  NL    ++     + ++ 
Sbjct: 852  EQQLQT---------SKQEIDTLTNEIEQLKNQYDIIRVDNDNLSKESLELKQILLSKTQ 902

Query: 598  VYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCS 657
              ++ + +    +  ++ I  LES   D  Q +  L+ ++D+ +     I Q   +Q+ S
Sbjct: 903  QLEEQLSLAQQQKGNIEIIQQLESIIVDNQQSIDQLKIEFDQSQQDNQSIKQ-SYNQLES 961

Query: 658  EIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQEN 717
             +     E Q   L    K+    +  +K     L+ +I   +  KE I  +    +Q  
Sbjct: 962  TLTLAQSENQ--RLLTENKQFITSLNEIK----SLFNSI---QQQKETIQLEFNQRLQS- 1011

Query: 718  MDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSR 777
                     + +EK  E+++ +    Q  I++      + QE++      +S L+ Y   
Sbjct: 1012 -------WSLDSEKYKEIISTLEQSNQKSIESYESKSLEFQEKE---NQFDSLLTNYNQL 1061

Query: 778  ICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVV 837
              +  +     E  R   ++        +Q  +        + D L+ +  +L      +
Sbjct: 1062 FSKYNDLATSNESNRLEFDQFKKDSNQSIQSLESLERSLKSENDNLLQQSNLLKSQLESI 1121

Query: 838  EKQ--------LLEIEHENKELQKKN-----------QILLEENQ------NLQISLSDM 872
            EKQ         LE+E +  EL K +           Q+L+  +Q       L+  +SD 
Sbjct: 1122 EKQKQDQLIPIQLELESKKCELSKLSSQFSEQTKQVTQLLISVDQYKISTNKLESQISDR 1181

Query: 873  QQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEF 932
             +  N L  KA   +  + E+   + QL  L+   K  T   + +I   KKE+E L  +F
Sbjct: 1182 NEEINNLKLKAIEINALKEENISLKDQLTKLKKAPKSQTDREKDMI---KKELEKLREKF 1238

Query: 933  N---TQIESAIRDKKVL---NEKYEKNIEYV----TQLEAQLQEYKNNIENLNMNVEELN 982
            N    +++ AI+DK+ +    +  E+ I+ +    T  E +L + K    +L  +V+  +
Sbjct: 1239 NAIDAKLKQAIQDKQTIQSEKQSLEREIKDLKRSHTSTETELDKLKKT--HLAADVKSKD 1296

Query: 983  KMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSM 1042
             + L    + + K Q Q      +  ++++K N  L++K EE++ LNQ     +     +
Sbjct: 1297 FIALNKSVEILTKSQEQLKSTIIELESDLSKKNIELEKKQEELVTLNQDKLEKEKKTNQL 1356

Query: 1043 VSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELK-ETKLT 1101
             SD+ S     T KLEN E ++ +++ +++D K   +E +    E +  IK+ +   K +
Sbjct: 1357 ESDHSSA----TIKLENYENQITQLTSEIIDLKSKFQEFK---SESESNIKQQEINLKES 1409

Query: 1102 FEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQS 1161
             ++N   T         + +SD     D             +  E  + I+E   LQE  
Sbjct: 1410 NDLNQQLTNDKF--ELTKQLSDLKVEFDKSKQLWST-----RSSESNDTIKE---LQESI 1459

Query: 1162 AKLNTELQECYTKIIQL-ETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAEL 1220
               + E Q    ++++L + +N +   ++ +N  Q  QL   L+ + + N+    ++  L
Sbjct: 1460 ISKDKERQLTSEQLVKLTDQINLKTWEYNDLN-SQCQQLTKTLQNVKSSNEQQEQSIVSL 1518

Query: 1221 RSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQ 1280
             S  S+ +     EI+++ + H  +   +  + +++L        S+ + L++  Q + Q
Sbjct: 1519 ESQTSAKIKSLELEISQIQENHRLE-VLELNRCKNQL--------SEKQTLME--QDNIQ 1567

Query: 1281 EETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXX 1340
                 I  + Q T  +N++   E ++ +L+ +  ++ ++IE  + + E EK         
Sbjct: 1568 LNERIIQLLHQKTKHENEILSMESNIIDLENQTKELKSKIETAQQDFEIEKNYHTGLNET 1627

Query: 1341 XXXXXXXXXXDLRTENQSYKQM--QEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDA 1398
                      +L   NQ+ +Q+  +   +   + +  Q ++              ++ D 
Sbjct: 1628 NTTTIKTMNEELTRSNQTIQQLLFKISKLEQTSLQTQQQQELQQATISAQQQKQQQLADD 1687

Query: 1399 EAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESE 1458
            + K  +L  +++L + E+ + T +  + +T++    E+      EY   I D    KE E
Sbjct: 1688 QEK-QQLYQKIKLIEKEL-ESTKQKNLYITEQFTLKES------EYLDTITDYVC-KEKE 1738

Query: 1459 LAILRLKMHENANHYETMQK-ESEIERVKLIEELNVKITESVSLNKQVAELNKALEEE-- 1515
                +  +  +A   + +     +++  K  ++  VK++ S  +N+    +   L++   
Sbjct: 1739 FEKSKASLKTSATKIQALNDIIKKLQEEKPQQQPVVKVSSSQVVNQNGQPIKSILKKPKL 1798

Query: 1516 -VAKTNEMQTALENQEIEIVTLNDEITNLQ-NMVRASSS-----KIQKHVSFASDTKQGR 1568
             +    ++Q   + +E+ + TLN   +N +   V ASS+      I K++   S+     
Sbjct: 1799 VIIPREQLQQPPQFKELTLSTLNSNDSNCEPESVSASSTLTSLQSISKYIGKRSEQTTLE 1858

Query: 1569 DEQLDNTMNKEL 1580
             +   +T+N  L
Sbjct: 1859 HDLTSSTLNLPL 1870



 Score =  122 bits (293), Expect = 1e-25
 Identities = 228/1123 (20%), Positives = 467/1123 (41%), Gaps = 99/1123 (8%)

Query: 473  EDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSN 532
            E + +I  + + L      ++K  ++  + E+L+  ++ I +    ++  N  + + +  
Sbjct: 545  ETIKKIKDLDDSLGISGQVKVKREDLDLIYEELEENKKLIEEYESTLELLNNQLDEKEIE 604

Query: 533  HKLKLKQMQKTIDNFSKVSDSNKEIVRLTEE----LHHLSQKVAELEEEK----GNLQLH 584
            HK  L  + +     +   + N+E++ + ++    +  L+ K+ E +++       L L 
Sbjct: 605  HKELLIIIDQWEQECTNRENQNQELLEIDQQSKQSIQQLNDKLLETKQQSKQSIDQLNLQ 664

Query: 585  LVDYDSGRMIESDVYKKMIE-MENLAETRLKAISLLESQKF----DLVQELHILQQKYDE 639
            L+D +S    ES   KK  E +  + E   +    LE + F    +  +++  L   Y +
Sbjct: 665  LIDIES----ESSKNKKSFENVLGVFEKSYRLAERLEDKYFTKEIESKKQIETLANSYLQ 720

Query: 640  VEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDL 699
            +E       QL  +Q  S+ K   L   I+        L   +     + +     I +L
Sbjct: 721  LETTYQ--QQLNINQQ-SQQKIQSLNNDIEQFKLVWVPLKDQVNGYFQENQMFKQYIIEL 777

Query: 700  ENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQE 759
            E +K + +  LQ  +++N  LT+ LE+   ++    + ++  E  ++IQ     + K+Q 
Sbjct: 778  E-EKYNTLIDLQKEVEQNY-LTNTLEQQRNDQYQIEINQLTTEYNNQIQQLESTNQKLQT 835

Query: 760  RDLY---------IENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQ 810
            + LY          + +E +L   K  I  L   I  ++++   +    D L     E +
Sbjct: 836  Q-LYNLLANATQSTQTLEQQLQTSKQEIDTLTNEIEQLKNQYDIIRVDNDNLSKESLELK 894

Query: 811  KAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLS 870
            +     T Q +E ++ LA     +  + +QL  I  +N+  Q  +Q+ +E +Q+ Q + S
Sbjct: 895  QILLSKTQQLEEQLS-LAQQQKGNIEIIQQLESIIVDNQ--QSIDQLKIEFDQSQQDNQS 951

Query: 871  DMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEI 930
             ++Q YN L    +   LA+SE+ +  T+ +   ++L  I     ++  QK    E +++
Sbjct: 952  -IKQSYNQL---ESTLTLAQSENQRLLTENKQFITSLNEIKSLFNSIQQQK----ETIQL 1003

Query: 931  EFNTQIESAIRDKK-------VLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEEL-N 982
            EFN +++S   D +        L +  +K+IE       + QE +N  ++L  N  +L +
Sbjct: 1004 EFNQRLQSWSLDSEKYKEIISTLEQSNQKSIESYESKSLEFQEKENQFDSLLTNYNQLFS 1063

Query: 983  KMN-LELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMS 1041
            K N L   ++  + +  Q    + Q I  +  L   LK +++ ++   Q+ N  +    S
Sbjct: 1064 KYNDLATSNESNRLEFDQFKKDSNQSIQSLESLERSLKSENDNLL---QQSNLLKSQLES 1120

Query: 1042 MVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLT 1101
            +    + +L     +LE+ + E+ ++S Q   S+Q  +  Q+L+    DQ K +   KL 
Sbjct: 1121 IEKQKQDQLIPIQLELESKKCELSKLSSQF--SEQTKQVTQLLI--SVDQYK-ISTNKLE 1175

Query: 1102 FEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQS 1161
             +++    E     + ++  + + N +             LK   + +  +E+ +++++ 
Sbjct: 1176 SQISDRNEE----INNLKLKAIEINALKEENISLKDQLTKLKKAPKSQTDREKDMIKKEL 1231

Query: 1162 AKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELR 1221
             KL  +      K+ Q       +       + +I  LK       TE D L  T     
Sbjct: 1232 EKLREKFNAIDAKLKQAIQDKQTIQSEKQSLEREIKDLKRSHTSTETELDKLKKT----- 1286

Query: 1222 SSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQE 1281
              +++ V  + F       + L + +   + T  EL   LS    + E+  + + +  Q+
Sbjct: 1287 -HLAADVKSKDFIALNKSVEILTKSQEQLKSTIIELESDLSKKNIELEKKQEELVTLNQD 1345

Query: 1282 ETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXX 1341
            +  K    E+ T   N+L+          E Y    NQI  L SEI D K  F       
Sbjct: 1346 KLEK----EKKT---NQLESDHSSATIKLENYE---NQITQLTSEIIDLKSKFQEFKSES 1395

Query: 1342 XXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAK 1401
                     +L+  N   +Q+         E   QL                R +++   
Sbjct: 1396 ESNIKQQEINLKESNDLNQQLTNDKF----ELTKQLSDLKVEFDKSKQLWSTRSSESNDT 1451

Query: 1402 VLELTHQLELKDSEIYQKTHEYTITLTQRND----EFENVRQQLVEYEKRIEDL-TYEKE 1456
            + EL   +  KD E  Q T E  + LT + +    E+ ++  Q  +  K ++++ +  ++
Sbjct: 1452 IKELQESIISKDKE-RQLTSEQLVKLTDQINLKTWEYNDLNSQCQQLTKTLQNVKSSNEQ 1510

Query: 1457 SELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEV 1516
             E +I+ L+   +A       K  E+E  ++ E   +++ E      Q++E    +E++ 
Sbjct: 1511 QEQSIVSLESQTSAK-----IKSLELEISQIQENHRLEVLELNRCKNQLSEKQTLMEQDN 1565

Query: 1517 AKTNEMQTALENQ----EIEIVTLNDEITNLQNMVRASSSKIQ 1555
             + NE    L +Q    E EI+++   I +L+N  +   SKI+
Sbjct: 1566 IQLNERIIQLLHQKTKHENEILSMESNIIDLENQTKELKSKIE 1608



 Score =  120 bits (290), Expect = 3e-25
 Identities = 260/1346 (19%), Positives = 548/1346 (40%), Gaps = 117/1346 (8%)

Query: 317  EIANMTELTKKIE--LLEHLNCQIR--QTNKELENKLATMGTESKAVSSPSKKGSPLISR 372
            ++A+   + KK E  +LE  N  ++  + N  L N ++T    S       K+ +  I  
Sbjct: 351  QVADANTMLKKYESEILELQNQLVKSEEINSLLRNTISTQEISSNNFKLGMKRFNDAIIG 410

Query: 373  KSGRNTASKMKSPWSQLSSETLNQDT--DKKINKNEIAKLEMVIQSLNKDLVDKEYVISE 430
             S  N   K K   + L    L +D    KKI K+E  K++ +  S N           E
Sbjct: 411  GSLINENKKKKKRRNTLDPSYLLKDKIIKKKIRKSENQKIKKIKNSENNISSSSSNSSGE 470

Query: 431  KDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELN 490
            +D                      E     +        T+ ED  +  +  +    + +
Sbjct: 471  EDDDDKDDENNYSINQDDKDDSNYEDDDDEDEDDDEESDTDNEDDEDNDEDNDDDDDD-D 529

Query: 491  DEIKDVNVKDLIEKLKSAE-EQITQLNDEIDAANKNMIKVKSNHKL--KLKQMQKTIDNF 547
            DE KD N+ +LIE L     ++I  L+D +  + +  +K +    +  +L++ +K I+ +
Sbjct: 530  DEFKD-NL-NLIEPLDDETIKKIKDLDDSLGISGQVKVKREDLDLIYEELEENKKLIEEY 587

Query: 548  SKVSDS-NKEIVRLTEELHHLSQKVAELEEE-----KGNLQLHLVDYDSGRMIESDVYKK 601
                +  N ++     E   L   + + E+E       N +L  +D  S + I+  +  K
Sbjct: 588  ESTLELLNNQLDEKEIEHKELLIIIDQWEQECTNRENQNQELLEIDQQSKQSIQQ-LNDK 646

Query: 602  MIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVE---DKLADISQLQSDQVCSE 658
            ++E +  ++   ++I  L  Q  D+  E    ++ ++ V    +K   +++   D+  + 
Sbjct: 647  LLETKQQSK---QSIDQLNLQLIDIESESSKNKKSFENVLGVFEKSYRLAERLEDKYFT- 702

Query: 659  IKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKED-------IMNKLQ 711
             K +  ++QI+ L+ S  +L    +      +Q    I+ L ND E        + +++ 
Sbjct: 703  -KEIESKKQIETLANSYLQLETTYQQQLNINQQSQQKIQSLNNDIEQFKLVWVPLKDQVN 761

Query: 712  NYIQEN-------MDLTDKLEKMS--AEKISELLAKINHEEQSKIQTQFGIDAKIQERDL 762
             Y QEN       ++L +K   +    +++ +       E+Q   Q Q  I+    E + 
Sbjct: 762  GYFQENQMFKQYIIELEEKYNTLIDLQKEVEQNYLTNTLEQQRNDQYQIEINQLTTEYNN 821

Query: 763  YIENIESELSKYKSRICRL----EESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTI 818
             I+ +ES   K ++++  L     +S   +E +  + +++ D L + +++ +  Y    +
Sbjct: 822  QIQQLESTNQKLQTQLYNLLANATQSTQTLEQQLQTSKQEIDTLTNEIEQLKNQYDIIRV 881

Query: 819  QEDEL----VNRLAVLMDHDRVVEKQLLEIEHE--NKELQKKNQILLEENQN----LQIS 868
              D L    +    +L+   + +E+QL   + +  N E+ ++ + ++ +NQ     L+I 
Sbjct: 882  DNDNLSKESLELKQILLSKTQQLEEQLSLAQQQKGNIEIIQQLESIIVDNQQSIDQLKIE 941

Query: 869  LSDMQQHYNALVEKANRTD----LAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKE 924
                QQ   ++ +  N+ +    LA+SE+ +  T+ +   ++L  I     ++  QK   
Sbjct: 942  FDQSQQDNQSIKQSYNQLESTLTLAQSENQRLLTENKQFITSLNEIKSLFNSIQQQK--- 998

Query: 925  IEDLEIEFNTQIESAIRDKK-------VLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMN 977
             E +++EFN +++S   D +        L +  +K+IE       + QE +N  ++L  N
Sbjct: 999  -ETIQLEFNQRLQSWSLDSEKYKEIISTLEQSNQKSIESYESKSLEFQEKENQFDSLLTN 1057

Query: 978  VEEL-NKMN-LELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNA 1035
              +L +K N L   ++  + +  Q    + Q I  +  L   LK +++ ++  +  + + 
Sbjct: 1058 YNQLFSKYNDLATSNESNRLEFDQFKKDSNQSIQSLESLERSLKSENDNLLQQSNLLKSQ 1117

Query: 1036 QVSYMSMVSDY--------ESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVRE 1087
              S      D         ESK  + +       E+ ++V++ L+   Q+      L  +
Sbjct: 1118 LESIEKQKQDQLIPIQLELESKKCELSKLSSQFSEQTKQVTQLLISVDQYKISTNKLESQ 1177

Query: 1088 QDDQIKELKETKL-TFEMNIPKTEGMIISSTIE-----PMSDDANNVDXXXXXXXXXXXX 1141
              D+ +E+   KL   E+N  K E + +   +      P S      D            
Sbjct: 1178 ISDRNEEINNLKLKAIEINALKEENISLKDQLTKLKKAPKSQTDREKDMIKKELEKLREK 1237

Query: 1142 LKVQEEE--EFIQERSVLQEQSAKLNTELQEC---YTKI-IQLETLNTELTGHDVVNQEQ 1195
                + +  + IQ++  +Q +   L  E+++    +T    +L+ L       DV +++ 
Sbjct: 1238 FNAIDAKLKQAIQDKQTIQSEKQSLEREIKDLKRSHTSTETELDKLKKTHLAADVKSKDF 1297

Query: 1196 INQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEH 1255
            I  L   +E L    + L ST+ EL S +S    +   +  EL    L Q + + +K  +
Sbjct: 1298 I-ALNKSVEILTKSQEQLKSTIIELESDLSKKNIELEKKQEELVT--LNQDKLEKEKKTN 1354

Query: 1256 ELRVQLSAFESKYEQLLDSVQSSTQEETN-KIVTMEQVTSLQNKLQDKEEHLRNLQEKYA 1314
            +L    S+   K E   + +   T E  + K    E  +  ++ ++ +E +L+   +   
Sbjct: 1355 QLESDHSSATIKLENYENQITQLTSEIIDLKSKFQEFKSESESNIKQQEINLKESNDLNQ 1414

Query: 1315 DVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEEN 1374
             + N    L  ++ D KV F                     N + K++QE SI++ ++E 
Sbjct: 1415 QLTNDKFELTKQLSDLKVEFDKSKQLWSTRSSES-------NDTIKELQE-SIISKDKER 1466

Query: 1375 AQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEF 1434
                +                ND  ++  +LT  L+   S   Q+        +Q + + 
Sbjct: 1467 QLTSEQLVKLTDQINLKTWEYNDLNSQCQQLTKTLQNVKSSNEQQEQSIVSLESQTSAKI 1526

Query: 1435 ENVRQQLVEYEK--RIEDLTYEK-ESELAILRLKMHENANHYETMQKESEIERVKLIEEL 1491
            +++  ++ + ++  R+E L   + +++L+  +  M ++  + +  ++  ++   K   E 
Sbjct: 1527 KSLELEISQIQENHRLEVLELNRCKNQLSEKQTLMEQD--NIQLNERIIQLLHQKTKHEN 1584

Query: 1492 NVKITES--VSLNKQVAELNKALE---EEVAKTNEMQTAL-ENQEIEIVTLNDEITNLQN 1545
             +   ES  + L  Q  EL   +E   ++        T L E     I T+N+E+T    
Sbjct: 1585 EILSMESNIIDLENQTKELKSKIETAQQDFEIEKNYHTGLNETNTTTIKTMNEELTRSNQ 1644

Query: 1546 MVRASSSKIQKHVSFASDTKQGRDEQ 1571
             ++    KI K    +  T+Q ++ Q
Sbjct: 1645 TIQQLLFKISKLEQTSLQTQQQQELQ 1670



 Score =  120 bits (289), Expect = 3e-25
 Identities = 222/1057 (21%), Positives = 453/1057 (42%), Gaps = 97/1057 (9%)

Query: 587  DYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLAD 646
            D D    I   V  K  +++ + E   +   L+E  +++   EL   Q    E+E K   
Sbjct: 552  DLDDSLGISGQVKVKREDLDLIYEELEENKKLIE--EYESTLELLNNQLDEKEIEHKELL 609

Query: 647  ISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDI 706
            I   Q +Q C+  ++ + +E ++    SK+ +  + + L   K+Q   +I  L     DI
Sbjct: 610  IIIDQWEQECTNRENQN-QELLEIDQQSKQSIQQLNDKLLETKQQSKQSIDQLNLQLIDI 668

Query: 707  MNKLQNYIQENMDLTDKLEKMS--AEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYI 764
             ++     +   ++    EK    AE++ +       E +SK Q +   ++ +Q    Y 
Sbjct: 669  ESESSKNKKSFENVLGVFEKSYRLAERLEDKY--FTKEIESKKQIETLANSYLQLETTYQ 726

Query: 765  ENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELV 824
            + +     + + +I  L   I   E  +       DQ+  Y QE Q  + +Y I+ +E  
Sbjct: 727  QQLNIN-QQSQQKIQSLNNDI---EQFKLVWVPLKDQVNGYFQENQM-FKQYIIELEEKY 781

Query: 825  NRLAVLMDHDRVVEKQLLE--IEHE-NKELQKK-NQILLEENQNLQISLSDMQ----QHY 876
            N    L+D  + VE+  L   +E + N + Q + NQ+  E N  +Q   S  Q    Q Y
Sbjct: 782  N---TLIDLQKEVEQNYLTNTLEQQRNDQYQIEINQLTTEYNNQIQQLESTNQKLQTQLY 838

Query: 877  NALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKK-EIEDLEI-EFNT 934
            N L      T   E +    + ++  L + ++++ +++  + V       E LE+ +   
Sbjct: 839  NLLANATQSTQTLEQQLQTSKQEIDTLTNEIEQLKNQYDIIRVDNDNLSKESLELKQILL 898

Query: 935  QIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQ 994
                 + ++  L ++ + NIE + QLE+ + + + +I+ L +  ++  + N  +   + Q
Sbjct: 899  SKTQQLEEQLSLAQQQKGNIEIIQQLESIIVDNQQSIDQLKIEFDQSQQDNQSIKQSYNQ 958

Query: 995  KQQT----QSPDY-----TEQYINEINKLNALLK--QKDEEIIAL--NQKINNAQVS--- 1038
             + T    QS +       +Q+I  +N++ +L    Q+ +E I L  NQ++ +  +    
Sbjct: 959  LESTLTLAQSENQRLLTENKQFITSLNEIKSLFNSIQQQKETIQLEFNQRLQSWSLDSEK 1018

Query: 1039 YMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKET 1098
            Y  ++S  E    +     E+   E Q    Q  DS   N     L  + +D     +  
Sbjct: 1019 YKEIISTLEQSNQKSIESYESKSLEFQEKENQF-DSLLTNYNQ--LFSKYNDLATSNESN 1075

Query: 1099 KLTFEMNIPKTEGMI--ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSV 1156
            +L F+     +   I  + S    +  + +N+             ++ Q++++ I  +  
Sbjct: 1076 RLEFDQFKKDSNQSIQSLESLERSLKSENDNLLQQSNLLKSQLESIEKQKQDQLIPIQLE 1135

Query: 1157 LQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLST 1216
            L+ +  +L+    +   +  Q+  L   +  + +      N+L+S++   N E +NL   
Sbjct: 1136 LESKKCELSKLSSQFSEQTKQVTQLLISVDQYKI----STNKLESQISDRNEEINNLKLK 1191

Query: 1217 VAELRSSISSAVDQRGFEIAELWKQHLAQ--READFQKTEHE-LRVQLSAFESKYEQLLD 1273
              E+ +     +  +  ++ +L K   +Q  RE D  K E E LR + +A ++K +Q + 
Sbjct: 1192 AIEINALKEENISLKD-QLTKLKKAPKSQTDREKDMIKKELEKLREKFNAIDAKLKQAIQ 1250

Query: 1274 ---SVQSSTQEETNKIVTMEQV-TSLQNKLQD-KEEHLR-NLQEKYADVINQ-IEILRSE 1326
               ++QS  Q    +I  +++  TS + +L   K+ HL  +++ K    +N+ +EIL   
Sbjct: 1251 DKQTIQSEKQSLEREIKDLKRSHTSTETELDKLKKTHLAADVKSKDFIALNKSVEILTKS 1310

Query: 1327 IEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXX 1386
             E  K                   DL  +N   ++ QE+ ++ +N++  + +K +     
Sbjct: 1311 QEQLK-----------STIIELESDLSKKNIELEKKQEE-LVTLNQDKLEKEKKTNQLES 1358

Query: 1387 XXXXXXXRVNDAEAKVLELTHQL-ELKD------SEIYQKTHEYTITLTQRNDEFENVRQ 1439
                   ++ + E ++ +LT ++ +LK       SE      +  I L + ND  + +  
Sbjct: 1359 DHSSATIKLENYENQITQLTSEIIDLKSKFQEFKSESESNIKQQEINLKESNDLNQQLTN 1418

Query: 1440 QLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQ-------KESEI---ERVKLIE 1489
               E  K++ DL  E +    +   +  E+ +  + +Q       KE ++   + VKL +
Sbjct: 1419 DKFELTKQLSDLKVEFDKSKQLWSTRSSESNDTIKELQESIISKDKERQLTSEQLVKLTD 1478

Query: 1490 ELNVKITESVSLNKQVAELNKALEEEVAKTNEMQ----TALENQ-EIEIVTLNDEITNLQ 1544
            ++N+K  E   LN Q  +L K L + V  +NE Q     +LE+Q   +I +L  EI+ +Q
Sbjct: 1479 QINLKTWEYNDLNSQCQQLTKTL-QNVKSSNEQQEQSIVSLESQTSAKIKSLELEISQIQ 1537

Query: 1545 NMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELL 1581
               R    ++ +  +  S+ KQ   EQ +  +N+ ++
Sbjct: 1538 ENHRLEVLELNRCKNQLSE-KQTLMEQDNIQLNERII 1573



 Score = 90.2 bits (214), Expect = 4e-16
 Identities = 227/1139 (19%), Positives = 465/1139 (40%), Gaps = 92/1139 (8%)

Query: 477  EIAKVQEQLKQELN-DEIKDVN--VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVK--- 530
            + AK  +++K     +++ D N  +K    ++   + Q+ + ++EI++  +N I  +   
Sbjct: 335  QFAKRAKRVKTNYKINQVADANTMLKKYESEILELQNQLVK-SEEINSLLRNTISTQEIS 393

Query: 531  -SNHKLKLKQMQKTIDNFSKVSDSNKEIVRLT--EELHHLSQKVAELEEEKGNLQLHLVD 587
             +N KL +K+    I   S ++++ K+  R    +  + L  K+ + +  K   Q     
Sbjct: 394  SNNFKLGMKRFNDAIIGGSLINENKKKKKRRNTLDPSYLLKDKIIKKKIRKSENQKIKKI 453

Query: 588  YDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKL--A 645
             +S   I S       E ++  +      S+ +  K D   E    + + D+ E      
Sbjct: 454  KNSENNISSSSSNSSGEEDDDDKDDENNYSINQDDKDDSNYEDDDDEDEDDDEESDTDNE 513

Query: 646  DISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKED 705
            D      D    +      ++ ++ +     E    I++L  D   + G +K    D + 
Sbjct: 514  DDEDNDEDNDDDDDDDDEFKDNLNLIEPLDDETIKKIKDLD-DSLGISGQVKVKREDLDL 572

Query: 706  IMNKLQNYIQENMDLTDKLEKMSAEKISELLAK-INHEEQSKIQTQFGIDAKIQERDLYI 764
            I  +L+    EN  L ++ E       ++L  K I H+E   I  Q+  +   +E     
Sbjct: 573  IYEELE----ENKKLIEEYESTLELLNNQLDEKEIEHKELLIIIDQWEQECTNRENQNQ- 627

Query: 765  ENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELV 824
            E +E +  + K  I +L + +  +E ++ S ++  DQL   L + +   SE +  +    
Sbjct: 628  ELLEID-QQSKQSIQQLNDKL--LETKQQS-KQSIDQLNLQLIDIE---SESSKNKKSFE 680

Query: 825  NRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKAN 884
            N L V     R+ E+  LE ++  KE++ K QI    N  LQ+  +  QQ  N   +   
Sbjct: 681  NVLGVFEKSYRLAER--LEDKYFTKEIESKKQIETLANSYLQLETT-YQQQLNINQQSQQ 737

Query: 885  RTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIE--SAIRD 942
            +     ++  +++     L+  +     E+Q      K+ I +LE ++NT I+    +  
Sbjct: 738  KIQSLNNDIEQFKLVWVPLKDQVNGYFQENQMF----KQYIIELEEKYNTLIDLQKEVEQ 793

Query: 943  KKVLNE-KYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQT--Q 999
              + N  + ++N +Y  ++     EY N I+ L    ++L      L+    Q  QT  Q
Sbjct: 794  NYLTNTLEQQRNDQYQIEINQLTTEYNNQIQQLESTNQKLQTQLYNLLANATQSTQTLEQ 853

Query: 1000 SPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSY----MSMVSDYESKLAQFTT 1055
                ++Q I+ +      LK + + I   N  ++   +      +S     E +L+    
Sbjct: 854  QLQTSKQEIDTLTNEIEQLKNQYDIIRVDNDNLSKESLELKQILLSKTQQLEEQLSLAQQ 913

Query: 1056 KLENMEEEMQRVSKQLLDSKQHNEELQILV--REQDDQIKELKETKLTFEMNIPKTEGMI 1113
            +  N+E  +Q++   ++D++Q  ++L+I     +QD+Q  +    +L   + + ++E   
Sbjct: 914  QKGNIEI-IQQLESIIVDNQQSIDQLKIEFDQSQQDNQSIKQSYNQLESTLTLAQSENQR 972

Query: 1114 ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYT 1173
            + +  +      N +               +Q+++E IQ     + QS  L++E    Y 
Sbjct: 973  LLTENKQFITSLNEIKSLFNS---------IQQQKETIQLEFNQRLQSWSLDSEK---YK 1020

Query: 1174 KIIQLETLNTELTGHDVVNQEQINQLKSK-LEQLNTEN--DNLLSTVAELRSSISSAVDQ 1230
            +II   TL          NQ+ I   +SK LE    EN  D+LL+   +L S  +     
Sbjct: 1021 EIIS--TLEQS-------NQKSIESYESKSLEFQEKENQFDSLLTNYNQLFSKYNDLATS 1071

Query: 1231 RGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLD-SVQSSTQEETNKIVTM 1289
                  E  +    Q + D  ++   L     + +S+ + LL  S    +Q E+ +    
Sbjct: 1072 N-----ESNRLEFDQFKKDSNQSIQSLESLERSLKSENDNLLQQSNLLKSQLESIEKQKQ 1126

Query: 1290 EQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXX 1349
            +Q+  +Q +L+ K+  L  L  ++++   Q+  L   ++  K++                
Sbjct: 1127 DQLIPIQLELESKKCELSKLSSQFSEQTKQVTQLLISVDQYKISTNKLESQISD------ 1180

Query: 1350 XDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLE-LTHQ 1408
               R E  +  +++   I  + EEN  LK               R  D   K LE L  +
Sbjct: 1181 ---RNEEINNLKLKAIEINALKEENISLKDQLTKLKKAPKSQTDREKDMIKKELEKLREK 1237

Query: 1409 LELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAI-LRLKMH 1467
                D+++ Q   +     +++      ++     +     +L   K++ LA  ++ K  
Sbjct: 1238 FNAIDAKLKQAIQDKQTIQSEKQSLEREIKDLKRSHTSTETELDKLKKTHLAADVKSKDF 1297

Query: 1468 ENANH-YETMQKESEIERVKLIE---ELNVKITESVSLNKQVAELNKALEEEVAKTNEMQ 1523
               N   E + K  E  +  +IE   +L+ K  E     +++  LN+   E+  KTN+++
Sbjct: 1298 IALNKSVEILTKSQEQLKSTIIELESDLSKKNIELEKKQEELVTLNQDKLEKEKKTNQLE 1357

Query: 1524 TALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQL--DNTMNKEL 1580
            +   +  I++    ++IT L + +    SK Q+  S +    + ++  L   N +N++L
Sbjct: 1358 SDHSSATIKLENYENQITQLTSEIIDLKSKFQEFKSESESNIKQQEINLKESNDLNQQL 1416


>UniRef50_A2DLG1 Cluster: Viral A-type inclusion protein, putative;
            n=1; Trichomonas vaginalis G3|Rep: Viral A-type inclusion
            protein, putative - Trichomonas vaginalis G3
          Length = 883

 Score =  132 bits (318), Expect = 1e-28
 Identities = 200/965 (20%), Positives = 438/965 (45%), Gaps = 113/965 (11%)

Query: 608  LAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQ 667
            +A+   +++S + S        L ++QQ+ DE+ ++L  I++L S    S+I++  +E Q
Sbjct: 1    MAQISAESVSKIRSADELKKTALKLIQQR-DEINEQLT-IAKLSSSAFESQIQAYKMELQ 58

Query: 668  IDALSASKKELALVIENLK--LDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLE 725
                  S    A + E +K  ++ E      K +  D  + + +L N I      T KLE
Sbjct: 59   ASQQKESSLN-AFIDEMMKEKMNFETKLNEQKQIMTDNNEKIKQLNNEIS-----TLKLE 112

Query: 726  KMSAE-KISEL-----LAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRIC 779
              S E K+++L     LA  N  +   ++ Q  I  + +E++  IE  + E  + + +I 
Sbjct: 113  NSSYEQKVNDLMQIINLAPSNPAQDQILELQRTIKQQNKEQNYLIEAFDIEKKELEEQIK 172

Query: 780  RLEESI--AVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRL-AVLMDHDRV 836
            +L+ +   + ++    + + +   L + +Q+ +   +      + L+N      ++++  
Sbjct: 173  KLQSNSNNSEIDSLLLAFQEEKTSLEAQIQDLKAQLANN--DTETLINTFHKEKLEYEEK 230

Query: 837  VEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKY 896
            V K L++ +   KEL+ K+    EE  +L  ++S+ +   + L ++  +    E E+ K 
Sbjct: 231  VNKLLVDNDKLQKELKNKD----EEQTSLLQAISEDKDKLSKLFDETQKQLNEEKENLKK 286

Query: 897  QTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKK-VLNEKYEKNIE 955
            Q +L  L   L+    + +  I  K   I+ ++ +  +++E  ++D++ ++  K E  ++
Sbjct: 287  QLKL--LNEQLENEKLQAKESIKAKDLVIQVIDSQ-RSELEQKLKDQEDIIKIKSENEVK 343

Query: 956  YVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLN 1015
                L  ++Q   N+I+ +  N    +  +L  ++  +  QQ +   Y  Q +       
Sbjct: 344  ----LSDEIQRLNNSIKEMQNN----SNSSLSDLNSQISSQQQKLNQYEAQDVQS----Q 391

Query: 1016 ALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSK 1075
            A +K    EI  L QK  N Q    +++S+ + KLA+    +++ +++++++ +   +  
Sbjct: 392  ATIKSLQTEIDVLKQKETNLQ----NLISEQDEKLAKQDQAIKDSQDKIKQLEEAAQNHS 447

Query: 1076 QHNEE-----LQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDX 1130
            +  +E     +Q++ +E DD   +  E     + N  K     I   ++ +S++ NN   
Sbjct: 448  EEEKEKQFEIIQMITKENDDLKAQNSEY---VKQNQEKDRQ--IEELVQSLSNENNN--- 499

Query: 1131 XXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDV 1190
                        K +EE E +   S L ++  +LNT++QE   ++ QL    TE     +
Sbjct: 500  ----NADIQKLYKEKEETELLI--SQLGDEITQLNTKIQEKVDEVNQL----TET----I 545

Query: 1191 VNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADF 1250
            +++E++      +  +  +N +L + +AEL ++IS    +   +  ++    L ++  + 
Sbjct: 546  LDKEEV------INAVTKDNSDLNNKIAELNNAISEMTKEITEKEEKI--NELNRKIEEL 597

Query: 1251 QKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQ 1310
                 E   +++ F SK  +L +S+     E  N   T   +  L N++++K+E +  L 
Sbjct: 598  NNVIKEKEEEINRFSSKISELNESINEKINEINN---TNTAINELNNQIKEKDEKINELN 654

Query: 1311 EKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNI 1370
             +  +  N+I+ L +E+ +                     + R +     ++ ++ I  I
Sbjct: 655  NQNQEKQNKIDEL-NELNN-------TVQQNETKFGELNKENREKENRINELNKE-IERI 705

Query: 1371 NEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQR 1430
            N  +++  K+              +   +  + EL   ++ K++EI QK       ++  
Sbjct: 706  NNSSSEKDKTIANLNESLLEKDNEITKKDELIKELQESVQTKETEINQKNE----LISSN 761

Query: 1431 NDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQ-KESEIERVKLIE 1489
            N + + + QQ+ E   +I D    KE+ L  +  K+H      ET+Q KE+EI +    E
Sbjct: 762  NTKIDELNQQINELNAQISD----KENSLKEITDKVHTLE---ETVQNKETEINQKN--E 812

Query: 1490 ELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRA 1549
            EL+ + T+   LN+ +++     + E+ + NE + +  N +IE   LN +I+N +N ++ 
Sbjct: 813  ELSERETKINELNEIISQK----DSEIQQKNE-EISSNNSKIE--ELNQQISNKENSLQE 865

Query: 1550 SSSKI 1554
             + K+
Sbjct: 866  LTDKV 870



 Score =  132 bits (318), Expect = 1e-28
 Identities = 196/894 (21%), Positives = 405/894 (45%), Gaps = 98/894 (10%)

Query: 471  NTEDVNEIAKVQEQLKQELN--DEIKDVNVKDLIEKLKSA--EEQITQLNDEIDAANKNM 526
            + E V++I    E  K  L    +  ++N +  I KL S+  E QI     E+ A+ +  
Sbjct: 5    SAESVSKIRSADELKKTALKLIQQRDEINEQLTIAKLSSSAFESQIQAYKMELQASQQK- 63

Query: 527  IKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLV 586
               +S+    + +M K   NF    +  K+I  +T+     ++K+ +L  E   L+L   
Sbjct: 64   ---ESSLNAFIDEMMKEKMNFETKLNEQKQI--MTDN----NEKIKQLNNEISTLKLENS 114

Query: 587  DYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQ--ELHILQQKYDEVEDKL 644
             Y+            ++++ NLA +      +LE Q+    Q  E + L + +D  + +L
Sbjct: 115  SYEQK-------VNDLMQIINLAPSNPAQDQILELQRTIKQQNKEQNYLIEAFDIEKKEL 167

Query: 645  AD-ISQLQSDQVCSEIKSVHL--EEQIDALSASKKELALVIENLKLDKEQLYGTIKDLEN 701
             + I +LQS+   SEI S+ L  +E+  +L A  ++L   + N   D E L  T    + 
Sbjct: 168  EEQIKKLQSNSNNSEIDSLLLAFQEEKTSLEAQIQDLKAQLANN--DTETLINTFHKEKL 225

Query: 702  DKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERD 761
            + E+ +NKL   + +N  L  +L+    E+ S LL  I+ E++ K+   F          
Sbjct: 226  EYEEKVNKL---LVDNDKLQKELKNKDEEQTS-LLQAIS-EDKDKLSKLF---------- 270

Query: 762  LYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQED 821
               +  + +L++ K     L++ + ++ ++   LE +  Q    ++ K         Q  
Sbjct: 271  ---DETQKQLNEEKEN---LKKQLKLLNEQ---LENEKLQAKESIKAKDLVIQVIDSQRS 321

Query: 822  ELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVE 881
            EL  +L    D  ++  +  +++   + E+Q+ N  + E   N   SLSD+    ++  +
Sbjct: 322  ELEQKLKDQEDIIKIKSENEVKL---SDEIQRLNNSIKEMQNNSNSSLSDLNSQISSQQQ 378

Query: 882  KANRTDL--AESEST--KYQTQ---LRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNT 934
            K N+ +    +S++T    QT+   L+  E+NL+ +  E    + ++ + I+D + +   
Sbjct: 379  KLNQYEAQDVQSQATIKSLQTEIDVLKQKETNLQNLISEQDEKLAKQDQAIKDSQDKIKQ 438

Query: 935  QIESAIRDKKVLNEKYEKNIEYVTQ----LEAQLQEYKNNIENLNMNVEEL-------NK 983
              E+A    +   EK  + I+ +T+    L+AQ  EY    +  +  +EEL       N 
Sbjct: 439  LEEAAQNHSEEEKEKQFEIIQMITKENDDLKAQNSEYVKQNQEKDRQIEELVQSLSNENN 498

Query: 984  MNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMV 1043
             N ++   + +K++T+      Q  +EI +LN  +++K +E+  L + I + +    ++ 
Sbjct: 499  NNADIQKLYKEKEETEL--LISQLGDEITQLNTKIQEKVDEVNQLTETILDKEEVINAVT 556

Query: 1044 SDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFE 1103
             D  S L     +L N   EM   +K++ + ++   EL   + E ++ IKE +E    F 
Sbjct: 557  KD-NSDLNNKIAELNNAISEM---TKEITEKEEKINELNRKIEELNNVIKEKEEEINRFS 612

Query: 1104 MNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAK 1163
              I +     ++ +I    ++ NN +             +++E++E I E +   ++   
Sbjct: 613  SKISE-----LNESINEKINEINNTNTAINELNN-----QIKEKDEKINELNNQNQEKQN 662

Query: 1164 LNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSS 1223
               EL E    + Q ET   EL   +   + +IN+L  ++E++N  +     T+A L  S
Sbjct: 663  KIDELNELNNTVQQNETKFGELNKENREKENRINELNKEIERINNSSSEKDKTIANLNES 722

Query: 1224 I---SSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLD-SVQSST 1279
            +    + + ++   I EL ++ +  +E +  +    +    +  +   +Q+ + + Q S 
Sbjct: 723  LLEKDNEITKKDELIKEL-QESVQTKETEINQKNELISSNNTKIDELNQQINELNAQISD 781

Query: 1280 QEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYAD---VINQIEILRSEIEDE 1330
            +E + K +T ++V +L+  +Q+KE  +    E+ ++    IN++  + S+ + E
Sbjct: 782  KENSLKEIT-DKVHTLEETVQNKETEINQKNEELSERETKINELNEIISQKDSE 834



 Score =  130 bits (315), Expect = 2e-28
 Identities = 167/817 (20%), Positives = 348/817 (42%), Gaps = 55/817 (6%)

Query: 445  KDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEK 504
            K+ +  + +L  Q+ +   +   +     +++ +       +Q++ND ++ +N    +  
Sbjct: 76   KEKMNFETKLNEQKQIMTDNNEKIKQLNNEISTLKLENSSYEQKVNDLMQIIN----LAP 131

Query: 505  LKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEEL 564
               A++QI +L   I   NK    +     ++ K++++ I      S+ N EI  L   L
Sbjct: 132  SNPAQDQILELQRTIKQQNKEQNYLIEAFDIEKKELEEQIKKLQSNSN-NSEIDSL---L 187

Query: 565  HHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKF 624
                ++   LE +  +L+  L + D+  +I +  +K+ +E E      L     L+ +  
Sbjct: 188  LAFQEEKTSLEAQIQDLKAQLANNDTETLINT-FHKEKLEYEEKVNKLLVDNDKLQKELK 246

Query: 625  DLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVH-----LEEQIDALSASKKELA 679
            +  +E   L Q   E +DKL+ +      Q+  E +++      L EQ++      KE  
Sbjct: 247  NKDEEQTSLLQAISEDKDKLSKLFDETQKQLNEEKENLKKQLKLLNEQLENEKLQAKESI 306

Query: 680  ----LVIENLKLDKEQLYGTIKDLEN------DKE----DIMNKLQNYIQENMDLTDKLE 725
                LVI+ +   + +L   +KD E+      + E    D + +L N I+E  + ++   
Sbjct: 307  KAKDLVIQVIDSQRSELEQKLKDQEDIIKIKSENEVKLSDEIQRLNNSIKEMQNNSNSSL 366

Query: 726  KMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIE---NIESELSKYKSRICRLE 782
                 +IS    K+N  E   +Q+Q  I +   E D+  +   N+++ +S+   ++ + +
Sbjct: 367  SDLNSQISSQQQKLNQYEAQDVQSQATIKSLQTEIDVLKQKETNLQNLISEQDEKLAKQD 426

Query: 783  ESIAVMEDRRYSLERKADQLGSYLQEKQ-KAYSEYTIQEDELVNRLAVLM----DHDRVV 837
            ++I   +D+   LE  A       +EKQ +     T + D+L  + +  +    + DR +
Sbjct: 427  QAIKDSQDKIKQLEEAAQNHSEEEKEKQFEIIQMITKENDDLKAQNSEYVKQNQEKDRQI 486

Query: 838  EKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQ 897
            E+ +  + +EN       Q L +E +  ++ +S +      L  K         E  +  
Sbjct: 487  EELVQSLSNENNN-NADIQKLYKEKEETELLISQLGDEITQLNTKIQEK---VDEVNQLT 542

Query: 898  TQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYV 957
              + D E  +  +T ++  L   K  E+ +   E   +I         LN K E+    +
Sbjct: 543  ETILDKEEVINAVTKDNSDLN-NKIAELNNAISEMTKEITEKEEKINELNRKIEELNNVI 601

Query: 958  TQLEAQLQEYKNNIENLNMNV-EELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNA 1016
             + E ++  + + I  LN ++ E++N++N      +    Q +  D   + INE+N  N 
Sbjct: 602  KEKEEEINRFSSKISELNESINEKINEINNTNTAINELNNQIKEKD---EKINELNNQNQ 658

Query: 1017 LLKQKDEEIIALNQKINNAQVSYMSMVSDY---ESKLAQFTTKLENMEEEMQRVSKQLLD 1073
              + K +E+  LN  +   +  +  +  +    E+++ +   ++E +        K + +
Sbjct: 659  EKQNKIDELNELNNTVQQNETKFGELNKENREKENRINELNKEIERINNSSSEKDKTIAN 718

Query: 1074 SKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISST--IEPMSDDANNVDXX 1131
              +   E    + ++D+ IKEL+E+  T E  I +   +I S+   I+ ++   N ++  
Sbjct: 719  LNESLLEKDNEITKKDELIKELQESVQTKETEINQKNELISSNNTKIDELNQQINELNAQ 778

Query: 1132 XXXXXXXXXXL--KVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHD 1189
                      +  KV   EE +Q +     Q    N EL E  TKI +L  + ++     
Sbjct: 779  ISDKENSLKEITDKVHTLEETVQNKETEINQK---NEELSERETKINELNEIISQKDSEI 835

Query: 1190 VVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISS 1226
                E+I+   SK+E+LN +  N  +++ EL   + S
Sbjct: 836  QQKNEEISSNNSKIEELNQQISNKENSLQELTDKVHS 872



 Score =  126 bits (305), Expect = 4e-27
 Identities = 177/824 (21%), Positives = 374/824 (45%), Gaps = 82/824 (9%)

Query: 300  IEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKL-ATMGTESKA 358
            I+   +EK   E K + +   MT+  +KI+ L +    ++  N   E K+   M   + A
Sbjct: 71   IDEMMKEKMNFETKLNEQKQIMTDNNEKIKQLNNEISTLKLENSSYEQKVNDLMQIINLA 130

Query: 359  VSSPSKKGSPLISRKSGRNT-------------ASKMKSPWSQLSSETLNQDTDKKI--N 403
             S+P++     + R   +                 +++    +L S + N + D  +   
Sbjct: 131  PSNPAQDQILELQRTIKQQNKEQNYLIEAFDIEKKELEEQIKKLQSNSNNSEIDSLLLAF 190

Query: 404  KNEIAKLEMVIQSLNKDLV--DKEYVIS--EKDTXXXXXXXXXXGKDTLIAQLQLEHQQH 459
            + E   LE  IQ L   L   D E +I+   K+             D    Q +L+++  
Sbjct: 191  QEEKTSLEAQIQDLKAQLANNDTETLINTFHKEKLEYEEKVNKLLVDNDKLQKELKNKDE 250

Query: 460  MEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKL-KSAEEQITQLNDE 518
             E  SL+     +ED ++++K+ ++ +++LN+E +  N+K  ++ L +  E +  Q  + 
Sbjct: 251  -EQTSLLQ--AISEDKDKLSKLFDETQKQLNEEKE--NLKKQLKLLNEQLENEKLQAKES 305

Query: 519  IDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEK 578
            I A +  +I+V  + + +L+Q  K  ++  K+   N+  V+L++E+  L+  + E++   
Sbjct: 306  IKAKDL-VIQVIDSQRSELEQKLKDQEDIIKIKSENE--VKLSDEIQRLNNSIKEMQ--- 359

Query: 579  GNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYD 638
             N    L D +S   I S   +K+ + E         I  L+++   L Q+   LQ    
Sbjct: 360  NNSNSSLSDLNS--QISSQ-QQKLNQYEAQDVQSQATIKSLQTEIDVLKQKETNLQNLIS 416

Query: 639  EVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVI--------ENLKLDKE 690
            E ++KLA   Q   D   S+ K   LEE     S  +KE    I        ++LK    
Sbjct: 417  EQDEKLAKQDQAIKD---SQDKIKQLEEAAQNHSEEEKEKQFEIIQMITKENDDLKAQNS 473

Query: 691  QLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEK---ISEL---LAKINHEEQ 744
            +     ++ +   E+++  L N    N D+  KL K   E    IS+L   + ++N + Q
Sbjct: 474  EYVKQNQEKDRQIEELVQSLSNENNNNADI-QKLYKEKEETELLISQLGDEITQLNTKIQ 532

Query: 745  SKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVM-------EDRRYSLER 797
             K+     +   I +++  I  +  + S   ++I  L  +I+ M       E++   L R
Sbjct: 533  EKVDEVNQLTETILDKEEVINAVTKDNSDLNNKIAELNNAISEMTKEITEKEEKINELNR 592

Query: 798  KADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQI 857
            K ++L + ++EK++  + ++ +  EL   +   ++        + E+ ++ KE  +K   
Sbjct: 593  KIEELNNVIKEKEEEINRFSSKISELNESINEKINEINNTNTAINELNNQIKEKDEKINE 652

Query: 858  LLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRI----THE 913
            L  +NQ  Q  + ++ +  N + +   +      E+ + + ++ +L   ++RI    + +
Sbjct: 653  LNNQNQEKQNKIDELNELNNTVQQNETKFGELNKENREKENRINELNKEIERINNSSSEK 712

Query: 914  HQTL------IVQKKKEIEDLEIEFNTQIESAIRDKKV-LNEKYE---KNIEYVTQLEAQ 963
             +T+      +++K  EI   + E   +++ +++ K+  +N+K E    N   + +L  Q
Sbjct: 713  DKTIANLNESLLEKDNEITKKD-ELIKELQESVQTKETEINQKNELISSNNTKIDELNQQ 771

Query: 964  LQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYI---NEINKLNALLKQ 1020
            + E    I +   +++E+    +  +++ VQ ++T+     E+      +IN+LN ++ Q
Sbjct: 772  INELNAQISDKENSLKEITD-KVHTLEETVQNKETEINQKNEELSERETKINELNEIISQ 830

Query: 1021 KDEEIIALNQKI--NNAQVSYMS-MVSDYESKLAQFTTKLENME 1061
            KD EI   N++I  NN+++  ++  +S+ E+ L + T K+ ++E
Sbjct: 831  KDSEIQQKNEEISSNNSKIEELNQQISNKENSLQELTDKVHSLE 874



 Score =  111 bits (266), Expect = 2e-22
 Identities = 180/914 (19%), Positives = 378/914 (41%), Gaps = 72/914 (7%)

Query: 696  IKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDA 755
            I+  +  K+  +  +Q   + N  LT  + K+S+      +     E Q+  Q +  ++A
Sbjct: 12   IRSADELKKTALKLIQQRDEINEQLT--IAKLSSSAFESQIQAYKMELQASQQKESSLNA 69

Query: 756  KIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSE 815
             I E      N E++L++ K           +M D    +++  +++ S L+ +  +Y +
Sbjct: 70   FIDEMMKEKMNFETKLNEQKQ----------IMTDNNEKIKQLNNEI-STLKLENSSYEQ 118

Query: 816  YTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQH 875
                  +++N        D+++E Q   I+ +NKE     +    E + L+  +  +Q +
Sbjct: 119  KVNDLMQIINLAPSNPAQDQILELQRT-IKQQNKEQNYLIEAFDIEKKELEEQIKKLQSN 177

Query: 876  YNALVEKANRTDLA-ESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNT 934
             N    + +   LA + E T  + Q++DL++ L    ++ +TLI    KE    ++E+  
Sbjct: 178  SNN--SEIDSLLLAFQEEKTSLEAQIQDLKAQLAN--NDTETLINTFHKE----KLEYEE 229

Query: 935  QIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQ 994
            ++   + D   L ++ +   E  T L   + E K+ +  L    ++      E + K ++
Sbjct: 230  KVNKLLVDNDKLQKELKNKDEEQTSLLQAISEDKDKLSKLFDETQKQLNEEKENLKKQLK 289

Query: 995  KQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFT 1054
                Q  +   Q    I   + +++  D +   L QK+ + Q   + + S+ E KL+   
Sbjct: 290  LLNEQLENEKLQAKESIKAKDLVIQVIDSQRSELEQKLKD-QEDIIKIKSENEVKLSDEI 348

Query: 1055 TKLENMEEEMQRVSKQLL---DSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEG 1111
             +L N  +EMQ  S   L   +S+  +++ ++   E  D   +     L  E+++ K + 
Sbjct: 349  QRLNNSIKEMQNNSNSSLSDLNSQISSQQQKLNQYEAQDVQSQATIKSLQTEIDVLKQKE 408

Query: 1112 MIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQEC 1171
              + + I    +     D             K+++ EE  Q  S   E+  +   E+ + 
Sbjct: 409  TNLQNLISEQDEKLAKQDQAIKDSQD-----KIKQLEEAAQNHS---EEEKEKQFEIIQM 460

Query: 1172 YTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNL--LSTVAELRSSISSAVD 1229
             TK  + + L  + + +   NQE+  Q++  ++ L+ EN+N   +  + + +      + 
Sbjct: 461  ITK--ENDDLKAQNSEYVKQNQEKDRQIEELVQSLSNENNNNADIQKLYKEKEETELLIS 518

Query: 1230 QRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTM 1289
            Q G EI +L            Q+   E+  QL+      E+++++V     +  NKI  +
Sbjct: 519  QLGDEITQL--------NTKIQEKVDEVN-QLTETILDKEEVINAVTKDNSDLNNKIAEL 569

Query: 1290 EQ-VTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXX 1348
               ++ +  ++ +KEE +  L  K  ++ N I+    E E+E   F              
Sbjct: 570  NNAISEMTKEITEKEEKINELNRKIEELNNVIK----EKEEEINRFSSKISELNESINEK 625

Query: 1349 XXDLRTENQSYKQMQEQ---SILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLEL 1405
              ++   N +  ++  Q       INE N Q ++               V   E K  EL
Sbjct: 626  INEINNTNTAINELNNQIKEKDEKINELNNQNQEKQNKIDELNELNNT-VQQNETKFGEL 684

Query: 1406 THQLELKDSEIYQKTHEY---TITLTQRNDEFENVRQQLVEYEKRIEDLT-YEKESELAI 1461
              +   K++ I +   E      + ++++    N+ + L+E +  I       KE + ++
Sbjct: 685  NKENREKENRINELNKEIERINNSSSEKDKTIANLNESLLEKDNEITKKDELIKELQESV 744

Query: 1462 LRLKMHENANHYETMQKESEIERV-KLIEELNVKITESVSLNKQVAELNKALEEEV---- 1516
               +   N  +       ++I+ + + I ELN +I++  +  K++ +    LEE V    
Sbjct: 745  QTKETEINQKNELISSNNTKIDELNQQINELNAQISDKENSLKEITDKVHTLEETVQNKE 804

Query: 1517 AKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTM 1576
             + N+    L  +E +I  LN+ I+   + ++  + +I  + S   +  Q    Q+ N  
Sbjct: 805  TEINQKNEELSERETKINELNEIISQKDSEIQQKNEEISSNNSKIEELNQ----QISNKE 860

Query: 1577 N--KELLDAVPRAE 1588
            N  +EL D V   E
Sbjct: 861  NSLQELTDKVHSLE 874



 Score =  102 bits (245), Expect = 7e-20
 Identities = 159/791 (20%), Positives = 328/791 (41%), Gaps = 72/791 (9%)

Query: 222 QENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQX 281
           Q+  + ++   K + +     IE+ D+    LEE  K L++      ++   LA + E+ 
Sbjct: 136 QDQILELQRTIKQQNKEQNYLIEAFDIEKKELEEQIKKLQSNSNNSEIDSLLLAFQ-EEK 194

Query: 282 XXXXXXXXXXXXXLAKQSIEPSC----EEKTEIEEKGSLEIANMTELTKKIELLEHLNCQ 337
                        LA    E       +EK E EEK +  + +  +L K+++  +     
Sbjct: 195 TSLEAQIQDLKAQLANNDTETLINTFHKEKLEYEEKVNKLLVDNDKLQKELKNKDEEQTS 254

Query: 338 IRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQD 397
           + Q   E ++KL+ +  E++   +  K+           N   ++K    QL +E L   
Sbjct: 255 LLQAISEDKDKLSKLFDETQKQLNEEKE-----------NLKKQLKLLNEQLENEKLQAK 303

Query: 398 TDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQ 457
              K     I  ++     L + L D+E +I  K              +  I ++Q    
Sbjct: 304 ESIKAKDLVIQVIDSQRSELEQKLKDQEDIIKIKSENEVKLSDEIQRLNNSIKEMQNNSN 363

Query: 458 QHMEGPSLIHVGTNTEDVN--EIAKVQEQLK-QELNDEI-----KDVNVKDLI----EKL 505
             +   +   + +  + +N  E   VQ Q   + L  EI     K+ N+++LI    EKL
Sbjct: 364 SSLSDLN-SQISSQQQKLNQYEAQDVQSQATIKSLQTEIDVLKQKETNLQNLISEQDEKL 422

Query: 506 KSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQ-KTIDNFSKVSD----SNKEIVRL 560
              ++ I    D+I    K + +   NH  + K+ Q + I   +K +D     N E V+ 
Sbjct: 423 AKQDQAIKDSQDKI----KQLEEAAQNHSEEEKEKQFEIIQMITKENDDLKAQNSEYVKQ 478

Query: 561 TEE----LHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAI 616
            +E    +  L Q ++       ++Q    + +   ++ S +  ++ ++    + ++  +
Sbjct: 479 NQEKDRQIEELVQSLSNENNNNADIQKLYKEKEETELLISQLGDEITQLNTKIQEKVDEV 538

Query: 617 SLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKK 676
           + L     D  + ++ + +   ++ +K+A+++   S ++  EI     EE+I+ L+   +
Sbjct: 539 NQLTETILDKEEVINAVTKDNSDLNNKIAELNNAIS-EMTKEI--TEKEEKINELNRKIE 595

Query: 677 ELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELL 736
           EL  VI+  + +  +    I +L     + +N++ N      +L +++ K   EKI+EL 
Sbjct: 596 ELNNVIKEKEEEINRFSSKISELNESINEKINEINNTNTAINELNNQI-KEKDEKINELN 654

Query: 737 AKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLE 796
            + N E+Q+KI     ++  +Q+ +     +  E  + ++RI  L + I  + +     +
Sbjct: 655 NQ-NQEKQNKIDELNELNNTVQQNETKFGELNKENREKENRINELNKEIERINNSSSEKD 713

Query: 797 RKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQ 856
           +    L   L EK    +E T ++DEL+  L         V+ +  EI  +N+ +   N 
Sbjct: 714 KTIANLNESLLEKD---NEIT-KKDELIKEL------QESVQTKETEINQKNELISSNNT 763

Query: 857 ILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQT 916
            + E NQ +    + +    N+L E  ++    E      +T++      L         
Sbjct: 764 KIDELNQQINELNAQISDKENSLKEITDKVHTLEETVQNKETEINQKNEELS-------- 815

Query: 917 LIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNM 976
              +++ +I +L  E  +Q +S I+ K   NE+   N   + +L  Q+   +N+++ L  
Sbjct: 816 ---ERETKINELN-EIISQKDSEIQQK---NEEISSNNSKIEELNQQISNKENSLQELTD 868

Query: 977 NVEELNKMNLE 987
            V  L   N E
Sbjct: 869 KVHSLETKNSE 879



 Score = 86.2 bits (204), Expect = 7e-15
 Identities = 132/680 (19%), Positives = 299/680 (43%), Gaps = 68/680 (10%)

Query: 173 LDLQEKIN----EKDQII-EAKNK--ATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENF 225
           L+ +EK+N    + D++  E KNK    T                 ++T++Q+ + +EN 
Sbjct: 225 LEYEEKVNKLLVDNDKLQKELKNKDEEQTSLLQAISEDKDKLSKLFDETQKQLNEEKENL 284

Query: 226 IA----MEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAAR------FEISLEHS-KL 274
                 +  + ++EK +  + I++KD+ I  ++     LE          +I  E+  KL
Sbjct: 285 KKQLKLLNEQLENEKLQAKESIKAKDLVIQVIDSQRSELEQKLKDQEDIIKIKSENEVKL 344

Query: 275 AQELEQXXXXXXXXXXXX-XXLAKQSIEPSCEEK--TEIEEKGSLEIANMTELTKKIELL 331
           + E+++               L+  + + S +++   + E +     A +  L  +I++L
Sbjct: 345 SDEIQRLNNSIKEMQNNSNSSLSDLNSQISSQQQKLNQYEAQDVQSQATIKSLQTEIDVL 404

Query: 332 EHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSS 391
           +     ++    E + KLA    + +A+     K   L   ++ +N + + K    ++  
Sbjct: 405 KQKETNLQNLISEQDEKLAK---QDQAIKDSQDKIKQL--EEAAQNHSEEEKEKQFEIIQ 459

Query: 392 ETLNQDTDKKINKNEIAK--------LEMVIQSL---NKDLVDKEYVISEKDTXXXXXXX 440
               ++ D K   +E  K        +E ++QSL   N +  D + +  EK+        
Sbjct: 460 MITKENDDLKAQNSEYVKQNQEKDRQIEELVQSLSNENNNNADIQKLYKEKEETELLISQ 519

Query: 441 XXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVN--V 498
              G +  I QL  + Q+ ++   +  +     D  E+     +   +LN++I ++N  +
Sbjct: 520 L--GDE--ITQLNTKIQEKVD--EVNQLTETILDKEEVINAVTKDNSDLNNKIAELNNAI 573

Query: 499 KDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNH----KLKLKQMQKTI-DNFSKVSDS 553
            ++ +++   EE+I +LN +I+  N N+IK K         K+ ++ ++I +  ++++++
Sbjct: 574 SEMTKEITEKEEKINELNRKIEELN-NVIKEKEEEINRFSSKISELNESINEKINEINNT 632

Query: 554 NKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDS-GRMIES------DVYKKMIEME 606
           N  I  L  ++    +K+ EL  +    Q  + + +     ++       ++ K+  E E
Sbjct: 633 NTAINELNNQIKEKDEKINELNNQNQEKQNKIDELNELNNTVQQNETKFGELNKENREKE 692

Query: 607 NLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSD-QVCSEIKSVHLE 665
           N      K I  + +   +  + +  L +   E ++++    +L  + Q   + K   + 
Sbjct: 693 NRINELNKEIERINNSSSEKDKTIANLNESLLEKDNEITKKDELIKELQESVQTKETEIN 752

Query: 666 EQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLE 725
           ++ + +S++  +    I+ L     +L   I D EN  ++I +K+   ++E +   +   
Sbjct: 753 QKNELISSNNTK----IDELNQQINELNAQISDKENSLKEITDKVHT-LEETVQNKETEI 807

Query: 726 KMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESI 785
               E++SE   KIN  E ++I +Q   D++IQ+++  I +  S++ +   +I   E S+
Sbjct: 808 NQKNEELSERETKIN--ELNEIISQK--DSEIQQKNEEISSNNSKIEELNQQISNKENSL 863

Query: 786 AVMEDRRYSLERKADQLGSY 805
             + D+ +SLE K  +  SY
Sbjct: 864 QELTDKVHSLETKNSEHRSY 883



 Score = 69.7 bits (163), Expect = 6e-10
 Identities = 111/508 (21%), Positives = 201/508 (39%), Gaps = 48/508 (9%)

Query: 96  NTLKQKEILMEKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKD 155
           N +K  + +       KE+   S++++                 +  DV   + TIK   
Sbjct: 340 NEVKLSDEIQRLNNSIKEMQNNSNSSLSDLNSQISSQQQKLNQYEAQDVQSQA-TIKSLQ 398

Query: 156 NALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTK 215
             + VL+ K   ++  I +  EK+ ++DQ I+                         +  
Sbjct: 399 TEIDVLKQKETNLQNLISEQDEKLAKQDQAIKDSQDKIKQLEEAAQNHSEEEKEKQFEII 458

Query: 216 QQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEAN---KLLEAARFEISLEHS 272
           Q +TK  ++  A  +E+  + Q   + IE     +S+    N   + L   + E  L  S
Sbjct: 459 QMITKENDDLKAQNSEYVKQNQEKDRQIEELVQSLSNENNNNADIQKLYKEKEETELLIS 518

Query: 273 KLAQELEQXXXXXXXXXXXXXXLA------KQSIEPSCEEKTEIEEK-GSLE--IANMT- 322
           +L  E+ Q              L       ++ I    ++ +++  K   L   I+ MT 
Sbjct: 519 QLGDEITQLNTKIQEKVDEVNQLTETILDKEEVINAVTKDNSDLNNKIAELNNAISEMTK 578

Query: 323 ELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTA--- 379
           E+T+K E +  LN +I + N  ++ K   +   S  +S  ++  +  I+  +  NTA   
Sbjct: 579 EITEKEEKINELNRKIEELNNVIKEKEEEINRFSSKISELNESINEKINEINNTNTAINE 638

Query: 380 --SKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQ-------SLNKDLVDKEYVISE 430
             +++K    ++ +E  NQ+ +K+   +E+ +L   +Q        LNK+  +KE  I+E
Sbjct: 639 LNNQIKEKDEKI-NELNNQNQEKQNKIDELNELNNTVQQNETKFGELNKENREKENRINE 697

Query: 431 KDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELN 490
            +            KD  IA L           SL+      E  NEI K  E +K EL 
Sbjct: 698 LNKEIERINNSSSEKDKTIANL---------NESLL------EKDNEITKKDELIK-ELQ 741

Query: 491 DEI--KDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFS 548
           + +  K+  +    E + S   +I +LN +I+  N   I  K N   ++     T++   
Sbjct: 742 ESVQTKETEINQKNELISSNNTKIDELNQQINELNA-QISDKENSLKEITDKVHTLE--E 798

Query: 549 KVSDSNKEIVRLTEELHHLSQKVAELEE 576
            V +   EI +  EEL     K+ EL E
Sbjct: 799 TVQNKETEINQKNEELSERETKINELNE 826



 Score = 54.0 bits (124), Expect = 3e-05
 Identities = 59/292 (20%), Positives = 120/292 (41%), Gaps = 12/292 (4%)

Query: 143 DVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXX 202
           D + L+N I E +NA+S +  ++   E  I +L  KI E + +I+ K +           
Sbjct: 558 DNSDLNNKIAELNNAISEMTKEITEKEEKINELNRKIEELNNVIKEKEEEINRFSSKISE 617

Query: 203 XXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEK-QRLLKDIESKDVRISSLEEANKLLE 261
                     +     T + E  +  + + KDEK   L    + K  +I  L E N  ++
Sbjct: 618 LNESINEKINEINNTNTAINE--LNNQIKEKDEKINELNNQNQEKQNKIDELNELNNTVQ 675

Query: 262 AARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANM 321
               +   +  +L +E  +              +   S E   ++KT      SL +   
Sbjct: 676 ----QNETKFGELNKENREKENRINELNKEIERINNSSSE---KDKTIANLNESL-LEKD 727

Query: 322 TELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGR-NTAS 380
            E+TKK EL++ L   ++    E+  K   + + +  +   +++ + L ++ S + N+  
Sbjct: 728 NEITKKDELIKELQESVQTKETEINQKNELISSNNTKIDELNQQINELNAQISDKENSLK 787

Query: 381 KMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKD 432
           ++      L     N++T+      E+++ E  I  LN+ +  K+  I +K+
Sbjct: 788 EITDKVHTLEETVQNKETEINQKNEELSERETKINELNEIISQKDSEIQQKN 839


>UniRef50_UPI00006CA4F0 Cluster: Viral A-type inclusion protein repeat
            containing protein; n=1; Tetrahymena thermophila
            SB210|Rep: Viral A-type inclusion protein repeat
            containing protein - Tetrahymena thermophila SB210
          Length = 1004

 Score =  131 bits (317), Expect = 1e-28
 Identities = 197/1005 (19%), Positives = 434/1005 (43%), Gaps = 77/1005 (7%)

Query: 562  EELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLA-ETRLKAISLLE 620
            + L  L ++V  LE++  + +      D     E   YK   E E +  E+ +K  S LE
Sbjct: 6    DSLDSLKKQVKTLEKQLADQERKAAMNDKKAQKEVSKYKLDAEKEKIEKESLIKERSELE 65

Query: 621  SQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHL----EEQIDALSASK- 675
                D V++L+I   K  +  DK +D +Q   + +  EI+ ++L     E +  L  S+ 
Sbjct: 66   ----DKVRKLNIELNKSSK--DKKSDENQTIINNLKKEIEKLNLMKPSPEMLAMLEMSEA 119

Query: 676  ---KELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKI 732
               +EL    +NL+ D ++    I+ L+    D + +  N +Q+ +   ++L++++    
Sbjct: 120  PTYQELFRNFQNLQNDNKKQEEEIEKLKKGAIDSIVEKTNELQQKVKQIEELQELNQSLE 179

Query: 733  SELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRR 792
              L  K N  E  +++ Q      +Q  +   E +E EL + K  + + +E +   E+ R
Sbjct: 180  RSL--KDNDYENQQMRDQL---RSVQSENNKAELLEEELKQIKVTLQQKDEQL---ENLR 231

Query: 793  YSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQ 852
              +E++  +    L ++Q    E  I+++       V+  ++  + +   +  +  KEL 
Sbjct: 232  QEVEKQQQKFQDQLTQEQSLKEEAIIEKER-----EVIKSYEEKMHEIDSQFRNNEKELL 286

Query: 853  KKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITH 912
            ++ +   E+ +N ++    +++   + + K  +T   + E  KYQ ++++LE+ +     
Sbjct: 287  QELRQCEEKLKNAELQAQSLEEEKQS-ISKGQKTQSDKIE-LKYQQKIKELEAQMDETQS 344

Query: 913  EHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIE 972
             H+ ++   K++ E++ ++    ++  I +   LNE+ E+  ++    E + QE    I+
Sbjct: 345  YHEKILSTTKQQYENMILQQEQSMQKQIDE---LNEQIEQLQKHNNSQEGKSQEANEAIK 401

Query: 973  NLNMNVEELNKMNLEL---IDKHVQKQQTQSPDYTE-------QYINEINKLNAL---LK 1019
                 +++L    +E    ++  +Q+ + Q  ++ +       Q + EI++L        
Sbjct: 402  AKEEQIKKLEDQIIEKQEQLETKIQEYEAQIFEFNKKHKEENSQLLAEIDRLKIYEEKFH 461

Query: 1020 QKDEEIIALNQKI-----NNAQVSYMSMVSDYESKL---AQFT---TKLENMEEEMQRVS 1068
            QK +   + NQ++     +    S  SM SD +  +   A+F    ++ E +E+  ++  
Sbjct: 462  QKKQAADSFNQELKKMIRDRRSSSSFSMNSDSDETMDVKAEFEKIRSEFEKVEQLNEKYE 521

Query: 1069 KQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNV 1128
            +++ +          ++ EQ+ +I+E     +  E  I + +  I SS I+    +A N+
Sbjct: 522  QEIAEKNAEISAFSEIITEQEKKIQEKTNLIIQNEKEIDQFKAEIESSAIKLKEKEA-NI 580

Query: 1129 DXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGH 1188
            +            L  Q +++ ++     + + + L   L     +I QL   NTEL   
Sbjct: 581  ENLKSQIKNATSSLTEQSDKQILELTEKSKAEISHLQDTLTAKLQEIKQLNAKNTELQQQ 640

Query: 1189 DVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREA 1248
            +   Q  ++Q K + E    +  NL   ++ L+      ++Q   ++ E  +Q  +++  
Sbjct: 641  NQNLQSAVDQNKHETESQLKKEQNLQQQISHLK----QLIEQSEAQLNEKNEQLTSEKNQ 696

Query: 1249 DFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRN 1308
            +       L+ Q+   +S   QL D + S T +  +    ++++T  + +L ++ + LR 
Sbjct: 697  N-----KSLKEQVINEKSSQNQLSDEIASLTAQNCDMEQKIKEMTVKEQQLFEESKELRT 751

Query: 1309 LQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSIL 1368
                    I Q E    E   +K                    L++E    KQ  E+   
Sbjct: 752  KLSNLETKIQQSE----ETLTKKNEALEKIKQEKKQILSETEGLKSEISQLKQNLEKQKN 807

Query: 1369 NINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTI-TL 1427
             I E+  Q+ + +               +   ++  L  QL L   E   K ++  I  L
Sbjct: 808  EIQEKQEQVNRLTQQIESQKSQENEMKQNLNKQIQAL--QLSLSKEEAIIKQNDSDIANL 865

Query: 1428 TQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHEN-ANHYETMQKESEIERVK 1486
             ++  + E  ++Q+ +   + E +   K+ EL   +L+  EN  N  +   ++  +E+ +
Sbjct: 866  KEKIAQKEEEKKQIQKKLAQNEGVDV-KQIELFQSQLEEKENQINQLKDQIQDMNLEQEQ 924

Query: 1487 LIEELNVKITE-SVSLNKQVAELNKALEEEVAKTNEMQTALENQE 1530
            ++ ELN +I   +V + +   ++N + E    + N++Q+ LE  E
Sbjct: 925  VVYELNKQINALNVEIKQLNLKINSSEELFQQEKNQLQSELEYAE 969



 Score =  128 bits (310), Expect = 9e-28
 Identities = 218/1005 (21%), Positives = 432/1005 (42%), Gaps = 114/1005 (11%)

Query: 626  LVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENL 685
            L +++  L+++  + E K A ++  ++ +  S+ K    +E+I+  S  K+   L  +  
Sbjct: 11   LKKQVKTLEKQLADQERKAA-MNDKKAQKEVSKYKLDAEKEKIEKESLIKERSELEDKVR 69

Query: 686  KLDKEQLYGTIKDLENDK-EDIMNKLQ------NYIQENMDLTDKLEKMSAEKISELLAK 738
            KL+ E L  + KD ++D+ + I+N L+      N ++ + ++   LE   A    EL   
Sbjct: 70   KLNIE-LNKSSKDKKSDENQTIINNLKKEIEKLNLMKPSPEMLAMLEMSEAPTYQELFRN 128

Query: 739  I-NHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKS--RICRLEESIA-VMEDRRYS 794
              N +  +K Q +     K    D  +E       K K    +  L +S+   ++D  Y 
Sbjct: 129  FQNLQNDNKKQEEEIEKLKKGAIDSIVEKTNELQQKVKQIEELQELNQSLERSLKDNDYE 188

Query: 795  LERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKK 854
             ++  DQL S   E  KA     + E+EL      L   D  +E    E+E + ++ Q  
Sbjct: 189  NQQMRDQLRSVQSENNKA----ELLEEELKQIKVTLQQKDEQLENLRQEVEKQQQKFQ-- 242

Query: 855  NQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQ-LRDLESNLKRITHE 913
            +Q+  E++   +  +   ++   +  EK +  D     + K   Q LR  E  LK    +
Sbjct: 243  DQLTQEQSLKEEAIIEKEREVIKSYEEKMHEIDSQFRNNEKELLQELRQCEEKLKNAELQ 302

Query: 914  HQTLIVQKKKEIEDLEIEFNTQIESAIRDK-KVLNEKYEKNIEYVTQ-LEAQLQEYKNNI 971
             Q+L  ++K+ I   +   + +IE   + K K L  + ++   Y  + L    Q+Y+N I
Sbjct: 303  AQSL-EEEKQSISKGQKTQSDKIELKYQQKIKELEAQMDETQSYHEKILSTTKQQYENMI 361

Query: 972  ----ENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIA 1027
                +++   ++ELN+  +E + KH   Q+ +S +            N  +K K+E+I  
Sbjct: 362  LQQEQSMQKQIDELNEQ-IEQLQKHNNSQEGKSQE-----------ANEAIKAKEEQIKK 409

Query: 1028 LNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVRE 1087
            L  +I   Q    + + +YE+++ +F  K    +EE  ++  ++   K + E+     + 
Sbjct: 410  LEDQIIEKQEQLETKIQEYEAQIFEFNKK---HKEENSQLLAEIDRLKIYEEKFHQKKQA 466

Query: 1088 QDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEE 1147
             D   +ELK  K+  +           SS+    SD    +D             K++ E
Sbjct: 467  ADSFNQELK--KMIRDRRS--------SSSFSMNSDSDETMDVKAEFE-------KIRSE 509

Query: 1148 EEFIQERSVLQEQS-AKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKS----- 1201
             E +++ +   EQ  A+ N E+      I + E    E T   + N+++I+Q K+     
Sbjct: 510  FEKVEQLNEKYEQEIAEKNAEISAFSEIITEQEKKIQEKTNLIIQNEKEIDQFKAEIESS 569

Query: 1202 --KLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRV 1259
              KL++     +NL S +    SS++   D++  E+ E  K  ++  +        E++ 
Sbjct: 570  AIKLKEKEANIENLKSQIKNATSSLTEQSDKQILELTEKSKAEISHLQDTLTAKLQEIK- 628

Query: 1260 QLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQ 1319
            QL+A  ++ +Q   ++QS+  +  NK  T  Q+   QN LQ +  HL+ L       I Q
Sbjct: 629  QLNAKNTELQQQNQNLQSAVDQ--NKHETESQLKKEQN-LQQQISHLKQL-------IEQ 678

Query: 1320 IEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKK 1379
             E   +E  ++                     L +E    K ++EQ ++N      QL  
Sbjct: 679  SEAQLNEKNEQ---------------------LTSEKNQNKSLKEQ-VINEKSSQNQLSD 716

Query: 1380 SSXXXXXXXXXXXXRVNDA---EAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFEN 1436
                          ++ +    E ++ E + +L  K S +  K  +   TLT++N+  E 
Sbjct: 717  EIASLTAQNCDMEQKIKEMTVKEQQLFEESKELRTKLSNLETKIQQSEETLTKKNEALEK 776

Query: 1437 VRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERV-KLIEELNVKI 1495
            ++Q+    +K+I   T   +SE++ L+  + +  N  E  +K+ ++ R+ + IE    + 
Sbjct: 777  IKQE----KKQILSETEGLKSEISQLKQNLEKQKN--EIQEKQEQVNRLTQQIESQKSQE 830

Query: 1496 TE-SVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKI 1554
             E   +LNKQ+  L  +L +E A   +  + + N + +I    +E   +Q  +  +    
Sbjct: 831  NEMKQNLNKQIQALQLSLSKEEAIIKQNDSDIANLKEKIAQKEEEKKQIQKKLAQNEGVD 890

Query: 1555 QKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDLAMYMLHQR 1599
             K +       + ++ Q+ N +  ++ D     E +  +Y L+++
Sbjct: 891  VKQIELFQSQLEEKENQI-NQLKDQIQDM--NLEQEQVVYELNKQ 932



 Score =  120 bits (289), Expect = 3e-25
 Identities = 177/919 (19%), Positives = 406/919 (44%), Gaps = 71/919 (7%)

Query: 233  KDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQE--LEQXXXXXXXXXX 290
            K + + L K +  ++ R +++ +     E +++++  E  K+ +E  +++          
Sbjct: 12   KKQVKTLEKQLADQE-RKAAMNDKKAQKEVSKYKLDAEKEKIEKESLIKERSELEDKVRK 70

Query: 291  XXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLA 350
                L K S +   +E   I      EI  +  +    E+L  L      T +EL     
Sbjct: 71   LNIELNKSSKDKKSDENQTIINNLKKEIEKLNLMKPSPEMLAMLEMSEAPTYQELFRNFQ 130

Query: 351  TMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSS-ETLNQDTDKKINKNEIAK 409
             +  ++K      +K            T ++++    Q+   + LNQ  ++ +  N+   
Sbjct: 131  NLQNDNKKQEEEIEKLKKGAIDSIVEKT-NELQQKVKQIEELQELNQSLERSLKDNDYEN 189

Query: 410  LEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVG 469
             +M  Q  +    + +  + E++            +     + ++E QQ      L    
Sbjct: 190  QQMRDQLRSVQSENNKAELLEEELKQIKVTLQQKDEQLENLRQEVEKQQQKFQDQLTQEQ 249

Query: 470  TNTEDV-----NEIAKVQEQLKQELNDEIKDVNVKDLI-------EKLKSAEEQITQLND 517
            +  E+       E+ K  E+   E++ + ++ N K+L+       EKLK+AE Q   L +
Sbjct: 250  SLKEEAIIEKEREVIKSYEEKMHEIDSQFRN-NEKELLQELRQCEEKLKNAELQAQSLEE 308

Query: 518  EIDAANKNMI----KVKSNHKLKLKQMQKTIDN----FSKVSDSNKEIVR--LTEELHHL 567
            E  + +K       K++  ++ K+K+++  +D       K+  + K+     + ++   +
Sbjct: 309  EKQSISKGQKTQSDKIELKYQQKIKELEAQMDETQSYHEKILSTTKQQYENMILQQEQSM 368

Query: 568  SQKVAELEEEKGNLQLHLVDYDSGRMIESDVYK-KMIEMENLAETRLKAISLLESQKFDL 626
             +++ EL E+   LQ H    +      ++  K K  +++ L +  ++    LE++  + 
Sbjct: 369  QKQIDELNEQIEQLQKHNNSQEGKSQEANEAIKAKEEQIKKLEDQIIEKQEQLETKIQEY 428

Query: 627  VQELHILQQKYDEVEDKL-ADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENL 685
              ++    +K+ E   +L A+I +L+  +     +  H ++Q  A  +  +EL  +I + 
Sbjct: 429  EAQIFEFNKKHKEENSQLLAEIDRLKIYE-----EKFHQKKQ--AADSFNQELKKMIRDR 481

Query: 686  KLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLA--KINHEE 743
            +        +  D   D +    K+++  ++   L +K E+  AEK +E+ A  +I  E+
Sbjct: 482  RSSSSFSMNSDSDETMDVKAEFEKIRSEFEKVEQLNEKYEQEIAEKNAEISAFSEIITEQ 541

Query: 744  QSKIQTQFGIDAKIQ-ERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQL 802
            + KIQ +  +  + + E D +   IES   K K +   +E   + +++   SL  ++D+ 
Sbjct: 542  EKKIQEKTNLIIQNEKEIDQFKAEIESSAIKLKEKEANIENLKSQIKNATSSLTEQSDKQ 601

Query: 803  GSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQK-------KN 855
               L EK KA  E +  +D L  +L  +    + +  +  E++ +N+ LQ        + 
Sbjct: 602  ILELTEKSKA--EISHLQDTLTAKLQEI----KQLNAKNTELQQQNQNLQSAVDQNKHET 655

Query: 856  QILLEENQNLQISLSDMQQHYNA----LVEKANRTDLAESESTKYQTQLRDLESNLKRIT 911
            +  L++ QNLQ  +S ++Q        L EK  +    ++++   + Q+ + +S+  +++
Sbjct: 656  ESQLKKEQNLQQQISHLKQLIEQSEAQLNEKNEQLTSEKNQNKSLKEQVINEKSSQNQLS 715

Query: 912  HEHQTLIVQK---KKEIEDLEIEFNTQIESA--IRDK-KVLNEKYEKNIEYVTQLEAQLQ 965
             E  +L  Q    +++I+++ ++     E +  +R K   L  K +++ E +T+    L+
Sbjct: 716  DEIASLTAQNCDMEQKIKEMTVKEQQLFEESKELRTKLSNLETKIQQSEETLTKKNEALE 775

Query: 966  EYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEI 1025
            + K   + +    E L K  +  + ++++KQ+ +  +  EQ      ++ +   Q++E  
Sbjct: 776  KIKQEKKQILSETEGL-KSEISQLKQNLEKQKNEIQEKQEQVNRLTQQIESQKSQENEMK 834

Query: 1026 IALNQKINNAQVSYM---SMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSK----QHN 1078
              LN++I   Q+S     +++   +S +A    K+   EEE +++ K+L  ++    +  
Sbjct: 835  QNLNKQIQALQLSLSKEEAIIKQNDSDIANLKEKIAQKEEEKKQIQKKLAQNEGVDVKQI 894

Query: 1079 EELQILVREQDDQIKELKE 1097
            E  Q  + E+++QI +LK+
Sbjct: 895  ELFQSQLEEKENQINQLKD 913



 Score =  106 bits (254), Expect = 6e-21
 Identities = 166/828 (20%), Positives = 361/828 (43%), Gaps = 65/828 (7%)

Query: 298  QSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESK 357
            QS+E S ++     ++   ++ ++     K ELLE    QI+ T ++ + +L  +  E +
Sbjct: 176  QSLERSLKDNDYENQQMRDQLRSVQSENNKAELLEEELKQIKVTLQQKDEQLENLRQEVE 235

Query: 358  AVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNE---IAKLEMVI 414
                  K    L   +S +  A   K      S E    + D +   NE   + +L    
Sbjct: 236  --KQQQKFQDQLTQEQSLKEEAIIEKEREVIKSYEEKMHEIDSQFRNNEKELLQELRQCE 293

Query: 415  QSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIH---VGTN 471
            + L    +  + +  EK +            +    Q   E +  M+     H   + T 
Sbjct: 294  EKLKNAELQAQSLEEEKQSISKGQKTQSDKIELKYQQKIKELEAQMDETQSYHEKILSTT 353

Query: 472  TEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKS 531
             +    +   QEQ  Q+  DE+ +  ++ L +   S E +  + N+ I A  + + K++ 
Sbjct: 354  KQQYENMILQQEQSMQKQIDELNE-QIEQLQKHNNSQEGKSQEANEAIKAKEEQIKKLED 412

Query: 532  NHKLKLKQMQKTIDNF-SKVSDSNKEIVRLTEELHHLSQKVAELE--EEKGNLQLHLVD- 587
                K +Q++  I  + +++ + NK   +  EE   L  ++  L+  EEK + +    D 
Sbjct: 413  QIIEKQEQLETKIQEYEAQIFEFNK---KHKEENSQLLAEIDRLKIYEEKFHQKKQAADS 469

Query: 588  --YDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYD-EVEDKL 644
               +  +MI          M + ++  +   +  E  + +  +++  L +KY+ E+ +K 
Sbjct: 470  FNQELKKMIRDRRSSSSFSMNSDSDETMDVKAEFEKIRSEF-EKVEQLNEKYEQEIAEKN 528

Query: 645  ADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKE 704
            A+IS   S+ +  + K +  +E+ + +  ++KE    I+  K + E     +K+ E + E
Sbjct: 529  AEISAF-SEIITEQEKKI--QEKTNLIIQNEKE----IDQFKAEIESSAIKLKEKEANIE 581

Query: 705  DIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQS---KIQTQFGIDAKIQERD 761
            ++ ++++N       LT++ +K   E   +  A+I+H + +   K+Q    ++AK  E  
Sbjct: 582  NLKSQIKN---ATSSLTEQSDKQILELTEKSKAEISHLQDTLTAKLQEIKQLNAKNTELQ 638

Query: 762  LYIENIESELSKYK----SRICR---LEESIA----VMEDRRYSLERKADQLGSYLQEKQ 810
               +N++S + + K    S++ +   L++ I+    ++E     L  K +QL S  + + 
Sbjct: 639  QQNQNLQSAVDQNKHETESQLKKEQNLQQQISHLKQLIEQSEAQLNEKNEQLTSE-KNQN 697

Query: 811  KAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLS 870
            K+  E  I E    N+L+   D    +  Q  ++E + KE+  K Q L EE++ L+  LS
Sbjct: 698  KSLKEQVINEKSSQNQLS---DEIASLTAQNCDMEQKIKEMTVKEQQLFEESKELRTKLS 754

Query: 871  DM----QQHYNALVEKANRTDLAESESTKYQTQLRDLE---SNLKRITHEHQTLIVQKKK 923
            ++    QQ    L +K    +  + E  +  ++   L+   S LK+   + +  I +K++
Sbjct: 755  NLETKIQQSEETLTKKNEALEKIKQEKKQILSETEGLKSEISQLKQNLEKQKNEIQEKQE 814

Query: 924  EIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNK 983
            ++  L  +  +Q       K+ LN++ +     +++ EA +++  ++I NL   + +  +
Sbjct: 815  QVNRLTQQIESQKSQENEMKQNLNKQIQALQLSLSKEEAIIKQNDSDIANLKEKIAQKEE 874

Query: 984  MNLELIDKHVQ------KQQTQSPDYTEQYINEINKLNALLK----QKDEEIIALNQKIN 1033
               ++  K  Q      KQ        E+  N+IN+L   ++    ++++ +  LN++IN
Sbjct: 875  EKKQIQKKLAQNEGVDVKQIELFQSQLEEKENQINQLKDQIQDMNLEQEQVVYELNKQIN 934

Query: 1034 NAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEEL 1081
               V    +     S    F  +   ++ E++      +++K +  E+
Sbjct: 935  ALNVEIKQLNLKINSSEELFQQEKNQLQSELEYAESAAIEAKMNYAEV 982



 Score = 37.1 bits (82), Expect = 4.0
 Identities = 55/287 (19%), Positives = 120/287 (41%), Gaps = 15/287 (5%)

Query: 147  LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXX 206
            +   IKE       L  + K + T + +L+ KI + ++ +  KN+A              
Sbjct: 728  MEQKIKEMTVKEQQLFEESKELRTKLSNLETKIQQSEETLTKKNEA----LEKIKQEKKQ 783

Query: 207  XXXXXEDTKQQMTKMQENFIAMEAEWKDEKQ---RLLKDIESKDVRISSLEE-ANKLLEA 262
                 E  K +++++++N    + E +++++   RL + IES+  + + +++  NK ++A
Sbjct: 784  ILSETEGLKSEISQLKQNLEKQKNEIQEKQEQVNRLTQQIESQKSQENEMKQNLNKQIQA 843

Query: 263  ARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMT 322
             +  +S E + + Q                    K+ I+    +   ++ K  +E+   +
Sbjct: 844  LQLSLSKEEAIIKQ--NDSDIANLKEKIAQKEEEKKQIQKKLAQNEGVDVK-QIELF-QS 899

Query: 323  ELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKM 382
            +L +K   +  L  QI+  N E E  +  +  +  A++   K+ +  I+  S      + 
Sbjct: 900  QLEEKENQINQLKDQIQDMNLEQEQVVYELNKQINALNVEIKQLNLKIN--SSEELFQQE 957

Query: 383  KSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVIS 429
            K+          +   + K+N  E+A      +   K+L  KEY IS
Sbjct: 958  KNQLQSELEYAESAAIEAKMNYAEVACERDYYECCYKNLC-KEYGIS 1003


>UniRef50_Q4Q3D8 Cluster: Putative uncharacterized protein; n=3;
            Leishmania|Rep: Putative uncharacterized protein -
            Leishmania major
          Length = 3167

 Score =  131 bits (317), Expect = 1e-28
 Identities = 219/1139 (19%), Positives = 460/1139 (40%), Gaps = 64/1139 (5%)

Query: 213  DTKQQMTKMQENFIAMEAEW-KDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271
            + + +  K +   +A E E  ++E +RL  +++        L    +  E        ++
Sbjct: 1657 EEEAERQKAENRRLAAELERAQEEAERLAAELDRAQEEAEKLAADLEKAEEDAERQKADN 1716

Query: 272  SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELL 331
             +LA + E+              LA   +E + EE  E ++  +  +A   EL +  E  
Sbjct: 1717 RRLAADNERLAAELDRAQEEAERLAAD-LEKA-EEDAERQKADNERLA--AELDRAQEEA 1772

Query: 332  EHLNCQIRQTNKELENKLATMG-TESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLS 390
            E L  ++ +  +E E   A +   + +A    + K          +  A K+ +   +  
Sbjct: 1773 ERLAAELEKAQEEAERLAAELEKAQEEAERQKADKERLAAELDRAQEEAEKLAADLEKAE 1832

Query: 391  SETLNQDTDKKI----NKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKD 446
             E   Q  D +     N+   A+LE   +   +   + E    E +             +
Sbjct: 1833 EEAERQKADNRRLAADNERLAAELERAQEEAERLAAELERAQEEAERLAAEVDRAQEEAE 1892

Query: 447  TLIAQLQL--EHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELND-EIKDVNVKDLIE 503
             L A L+   E  +  +  +      N     E+ + QE+ ++   + E  +   + L  
Sbjct: 1893 QLAADLEKAEEEAERQKADNRRLAADNERLAAELDRAQEEAERLAAELEKAEEEAERLAA 1952

Query: 504  KLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEE 563
            +L+ A+E+  +L  +++ A ++  + K++++    ++ +  +   +++    ++ R  EE
Sbjct: 1953 ELEKAQEEAERLAADLEKAEEDAERQKADNEQLAAELNRAQEEAKRLA---ADLERAQEE 2009

Query: 564  LHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQK 623
               L+ ++   +EE   L   L         E D  ++  + E LA    +  + LE  +
Sbjct: 2010 AEKLAAELERAQEEAEKLAADL------EKAEEDAERQKADNERLAADNERLAAELERTQ 2063

Query: 624  FDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIE 683
             +  +    L++  ++ E + AD  QL ++   ++ ++  L   ++      ++LA  +E
Sbjct: 2064 EEAEKLAADLEKAEEDAERQKADNEQLAAELNRAQEEAKRLAADLERAQEEAEKLAAELE 2123

Query: 684  NLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMS--AEKISELLAKINH 741
              + + E+L   ++  E D E      +    +N  L  +LE+    AEK++  L K   
Sbjct: 2124 RAQEEAEKLAADLEKAEEDAERQKADNRRLAADNERLAAELERTQEEAEKLAADLEKAEE 2183

Query: 742  EEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQ 801
            E + +      + A++       E + ++L K +      E   A  E     L R  ++
Sbjct: 2184 EAERQKADNERLAAELDRAQEEAEKLAADLEKAEEDA---ERQKADNERLAAELNRAQEE 2240

Query: 802  LGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEE 861
                  + +KA  +   Q+ +     A L       E+   E+E   +E +K    L + 
Sbjct: 2241 AEKLAADLEKAEEDAERQKADNERLAAELNRAQEEAERLAAELERAQEEAEKLAADLEKA 2300

Query: 862  NQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQK 921
             +  +   +D +Q    L       +   +E  K Q +   L ++L++   E +    ++
Sbjct: 2301 EEEAERQKADNEQLAAELNRAQEEAEKLAAELEKAQEEAEKLAADLEKAEEEAE----RQ 2356

Query: 922  KKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEEL 981
            K + E L  E N   E A +    L +  E+      +LE   +E +     LN   EE 
Sbjct: 2357 KADNERLAAELNRAQEEAEKLAAELEKAQEEAERLAAELEKAQEEAERLAAELNRAQEEA 2416

Query: 982  NKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMS 1041
             ++  EL  +  Q++  +     ++   E  +L A L++  EE   L  ++N AQ     
Sbjct: 2417 ERLAAEL--ERAQEEAERLAAELDRAQEEAERLAAELERAQEEAERLAAELNRAQEEAEK 2474

Query: 1042 MVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLT 1101
            + ++ E   AQ   + E  +   +R++ +L   ++  EE + L  E +   +E +  +L 
Sbjct: 2475 LAANLEK--AQ--EEAERQKAHNERLAAEL---ERAREEAERLAAELEKAQEEAE--RLA 2525

Query: 1102 FEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEE-EEFIQERSVLQEQ 1160
             E+   + E   +++ +E   ++A  +              K QEE E    E    QE+
Sbjct: 2526 AELEKAREEAERLAAELERAREEAERLAAELE---------KAQEEAERLAAELDRAQEE 2576

Query: 1161 SAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNL---LSTV 1217
            + KL  +L++   +  + +  N  L       QE+  +L ++LE+   E + L   L   
Sbjct: 2577 AEKLAADLEKAEEEAERQKADNERLAAELDRAQEEAERLAAELERAQEEAERLAAELDRA 2636

Query: 1218 AELRSSISSAVDQRGFEIAELWKQ-HLAQREADFQKTEHE-LRVQLSAFESKYEQLLDSV 1275
             E    +++ +D+   E  +L      A+ EA+ QK ++E L  +L+  + + E+L   +
Sbjct: 2637 QEEAERLAAELDRAQEEAEKLAADLEKAEEEAERQKADNERLAAELNRAQEEAERLAAEL 2696

Query: 1276 QSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVIN-QIEILRSEIEDEKVA 1333
            + + QEE  K+        L+   +D E    + +   AD      E+ R++ E E++A
Sbjct: 2697 EKA-QEEAEKL-----AADLEKAEEDAERQKADNRRLAADNERLAAELDRAQEEAERLA 2749



 Score =  131 bits (316), Expect = 2e-28
 Identities = 279/1433 (19%), Positives = 547/1433 (38%), Gaps = 94/1433 (6%)

Query: 147  LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXX 206
            L    +E +   + L    +  E    DL EK  E+ +  +A+N+               
Sbjct: 1044 LERAQEEAERLAAELDRAQEEAEKLAADL-EKAEEEAERQKAENRRLAAELERAQEEAER 1102

Query: 207  XXXXXEDTKQQMTKMQENFIAMEAE---WKDEKQRLLKDIE---SKDVRISS-LEEANKL 259
                 +  +++  K+  +    E E    K E +RL  ++E    +  R+++ LE A + 
Sbjct: 1103 LAAELDRAQEEAEKLAADLEKAEEEAERQKAENRRLAAELERAQEEAERLAAELERAQEE 1162

Query: 260  LEAARFEISL---EHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSL 316
             E    E+     E  KLA ELE+               A++  E    E  + +E+   
Sbjct: 1163 AERLAAELDRAQEEAEKLAAELERAQEEAEKLAAELDR-AQEEAERLAAELEKAQEEAER 1221

Query: 317  EIANMTELTKKIELLEHLNCQIRQTNKELENKLATMG-TESKAVSSPSKKGSPLISRKSG 375
              A   EL K  E  E L  ++ +  +E E   A +   E  A    ++K          
Sbjct: 1222 LAA---ELEKTQEEAERLAAELEKAQEEAERLAADLEKAEEDAERQKAEKERLAAEVDRA 1278

Query: 376  RNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXX 435
            +  A K+ +   +   +   Q  D +    E+ + +   + L  DL +K    +E+D   
Sbjct: 1279 QEEAEKLAADLEKAEEDAERQKADNERLAAELNRAQEEAERLAADL-EK----AEEDAER 1333

Query: 436  XXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKD 495
                      D      +LE  Q         +    E+   +A   E  K E + E + 
Sbjct: 1334 QKADNRRLAADNERLAAELERAQEEAERLAAELDRAQEEAERLAADLE--KAEEDAERQK 1391

Query: 496  VNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNK 555
             + + L  +L  A+E+  +L  +++ A ++  + K++++      ++     +++  + +
Sbjct: 1392 ADNERLAAELDRAQEEAEKLAADLEKAEEDAERQKADNERLAADNERLA---AELDRAQE 1448

Query: 556  EIVRLTEELHHLSQKVAELEEEKGNLQLHLVD-YDSGRMIESDVYKKMIEMENLAETRLK 614
            E  RL  +L    +     + +   L   L    +    + +++ K   E E LA    K
Sbjct: 1449 EAERLAADLEKAEEDAERQKADNERLAAELDRAQEEAERLAAELEKAQEEAERLAAELEK 1508

Query: 615  AISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSAS 674
            A    E QK D  +    L +  +E E   AD+ + + D    +  +  L  +++     
Sbjct: 1509 AQEEAERQKADKERLAAELDRAQEEAEKLAADLEKAEEDAERQKADNERLAAELNRAQEE 1568

Query: 675  KKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISE 734
             + LA  +E  + D E+     + L  D E +  +L+   +E   L  +LEK   E   +
Sbjct: 1569 AERLAADLEKAEEDAERQKADNRRLAADNERLAAELERAQEEAERLAAELEKAQEEAERQ 1628

Query: 735  LLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYS 794
               K + E  +    +   +A+    DL     E+E  K ++R    E   A  E  R +
Sbjct: 1629 ---KADKERLAAELDRAQEEAEKLAADLEKAEEEAERQKAENRRLAAELERAQEEAERLA 1685

Query: 795  LE-----RKADQLGSYLQ------EKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQL-- 841
             E      +A++L + L+      E+QKA +     ++E   RLA  +D  +   ++L  
Sbjct: 1686 AELDRAQEEAEKLAADLEKAEEDAERQKADNRRLAADNE---RLAAELDRAQEEAERLAA 1742

Query: 842  -LEIEHENKELQK-KNQILLEENQNLQISLSDMQQHYNALVEKANR----TDLAESESTK 895
             LE   E+ E QK  N+ L  E    Q     +        E+A R     + A+ E+ +
Sbjct: 1743 DLEKAEEDAERQKADNERLAAELDRAQEEAERLAAELEKAQEEAERLAAELEKAQEEAER 1802

Query: 896  YQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIE 955
             +     L + L R   E + L    +K  E+ E +          D + L  + E+  E
Sbjct: 1803 QKADKERLAAELDRAQEEAEKLAADLEKAEEEAERQ-KADNRRLAADNERLAAELERAQE 1861

Query: 956  YVTQLEAQLQEYKNNIENLNMNVEELNKMNLEL---IDKHVQKQQTQSPDYTEQYINEIN 1012
               +L A+L+  +   E L   V+   +   +L   ++K  ++ + Q  D   +   +  
Sbjct: 1862 EAERLAAELERAQEEAERLAAEVDRAQEEAEQLAADLEKAEEEAERQKAD-NRRLAADNE 1920

Query: 1013 KLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLL 1072
            +L A L +  EE   L  ++  A+     + ++ E    +      ++E+  +   +Q  
Sbjct: 1921 RLAAELDRAQEEAERLAAELEKAEEEAERLAAELEKAQEEAERLAADLEKAEEDAERQKA 1980

Query: 1073 DSKQHNEELQILVREQDDQIKELKET-----KLTFEMNIPKTEGMIISSTIEPMSDDANN 1127
            D++Q   EL     E      +L+       KL  E+   + E   +++ +E   +DA  
Sbjct: 1981 DNEQLAAELNRAQEEAKRLAADLERAQEEAEKLAAELERAQEEAEKLAADLEKAEEDAER 2040

Query: 1128 VDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTG 1187
                              + E    E    QE++ KL  +L++      + +  N +L  
Sbjct: 2041 QKADNERLAA--------DNERLAAELERTQEEAEKLAADLEKAEEDAERQKADNEQLAA 2092

Query: 1188 HDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISS-AVD-QRGFEIAELWKQHLAQ 1245
                 QE+  +L + LE+   E + L + +   +      A D ++  E AE  K    +
Sbjct: 2093 ELNRAQEEAKRLAADLERAQEEAEKLAAELERAQEEAEKLAADLEKAEEDAERQKADNRR 2152

Query: 1246 READFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEH 1305
              AD ++    L  +L   + + E+L   ++ + +E   +    E++ +  ++ Q++ E 
Sbjct: 2153 LAADNER----LAAELERTQEEAEKLAADLEKAEEEAERQKADNERLAAELDRAQEEAEK 2208

Query: 1306 LRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQ 1365
            L    EK  +     +  R + ++E++A                 +   E+   ++   +
Sbjct: 2209 LAADLEKAEE-----DAERQKADNERLAAELNRAQEEAEKLAADLEKAEEDAERQKADNE 2263

Query: 1366 SI---LNINEEN-----AQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIY 1417
             +   LN  +E      A+L+++                +AE +  +   QL  + +   
Sbjct: 2264 RLAAELNRAQEEAERLAAELERAQEEAEKLAADLEKAEEEAERQKAD-NEQLAAELNRAQ 2322

Query: 1418 QKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQ 1477
            ++  +    L +  +E E +   L + E+  E    + E   A L  +  E A       
Sbjct: 2323 EEAEKLAAELEKAQEEAEKLAADLEKAEEEAERQKADNERLAAELN-RAQEEAEKLAAEL 2381

Query: 1478 KESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQE 1530
            ++++ E  +L  EL     E+  L    AELN+A EE      E++ A E  E
Sbjct: 2382 EKAQEEAERLAAELEKAQEEAERL---AAELNRAQEEAERLAAELERAQEEAE 2431



 Score =  126 bits (304), Expect = 5e-27
 Identities = 258/1379 (18%), Positives = 545/1379 (39%), Gaps = 90/1379 (6%)

Query: 217  QMTKMQENFIAMEAEW---KDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSK 273
            ++ + QE    + AE    ++E +RL  D+E  +      +  N+ L A       E  K
Sbjct: 1351 ELERAQEEAERLAAELDRAQEEAERLAADLEKAEEDAERQKADNERLAAELDRAQEEAEK 1410

Query: 274  LAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEH 333
            LA +LE+              LA  + E    E    +E+     A++ +  +  E    
Sbjct: 1411 LAADLEKAEEDAERQKADNERLAADN-ERLAAELDRAQEEAERLAADLEKAEEDAE---- 1465

Query: 334  LNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSET 393
               + +  N+ L  +L     E++ +++  +K      R +     ++ ++   +   E 
Sbjct: 1466 ---RQKADNERLAAELDRAQEEAERLAAELEKAQEEAERLAAELEKAQEEAERQKADKER 1522

Query: 394  LNQDTDKKINKNE--IAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXG--KDTLI 449
            L  + D+   + E   A LE   +   +   D E + +E +              K    
Sbjct: 1523 LAAELDRAQEEAEKLAADLEKAEEDAERQKADNERLAAELNRAQEEAERLAADLEKAEED 1582

Query: 450  AQLQLEHQQHMEGPS---LIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLK 506
            A+ Q    + +   +      +    E+   +A   E+ ++E   E +  + + L  +L 
Sbjct: 1583 AERQKADNRRLAADNERLAAELERAQEEAERLAAELEKAQEEA--ERQKADKERLAAELD 1640

Query: 507  SAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHH 566
             A+E+  +L  +++ A +   + K+ ++    ++++  +   +++    E+ R  EE   
Sbjct: 1641 RAQEEAEKLAADLEKAEEEAERQKAENRRLAAELERAQEEAERLA---AELDRAQEEAEK 1697

Query: 567  LSQKVAELEE--EKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKF 624
            L+  + + EE  E+       +  D+ R+  +++ +   E E LA    KA    E QK 
Sbjct: 1698 LAADLEKAEEDAERQKADNRRLAADNERLA-AELDRAQEEAERLAADLEKAEEDAERQKA 1756

Query: 625  DLVQELHILQQKYDEVEDKLADISQLQ--SDQVCSEIKSVHLEEQIDALSASKKELALVI 682
            D  +    L +  +E E   A++ + Q  ++++ +E++    +E+ +   A K+ LA  +
Sbjct: 1757 DNERLAAELDRAQEEAERLAAELEKAQEEAERLAAELEKA--QEEAERQKADKERLAAEL 1814

Query: 683  ENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHE 742
            +  + + E+L   ++  E + E      +    +N  L  +LE+ + E+   L A++   
Sbjct: 1815 DRAQEEAEKLAADLEKAEEEAERQKADNRRLAADNERLAAELER-AQEEAERLAAELERA 1873

Query: 743  EQSKIQTQFGIDAKIQERDLY---IENIESELSKYKS---RICRLEESIAVMEDR-RYSL 795
            ++   +    +D   +E +     +E  E E  + K+   R+    E +A   DR +   
Sbjct: 1874 QEEAERLAAEVDRAQEEAEQLAADLEKAEEEAERQKADNRRLAADNERLAAELDRAQEEA 1933

Query: 796  ERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQ----------LLEIE 845
            ER A +L    +E ++  +E    ++E     A L   +   E+Q          L   +
Sbjct: 1934 ERLAAELEKAEEEAERLAAELEKAQEEAERLAADLEKAEEDAERQKADNEQLAAELNRAQ 1993

Query: 846  HENKELQKKNQILLEENQNLQISLSDMQQHYNAL---VEKANR-TDLAESESTKYQTQLR 901
             E K L    +   EE + L   L   Q+    L   +EKA    +  ++++ +      
Sbjct: 1994 EEAKRLAADLERAQEEAEKLAAELERAQEEAEKLAADLEKAEEDAERQKADNERLAADNE 2053

Query: 902  DLESNLKRITHEHQTLIVQKKKEIEDLEIE------FNTQIESAIRDKKVLNEKYEKNIE 955
             L + L+R   E + L    +K  ED E +         ++  A  + K L    E+  E
Sbjct: 2054 RLAAELERTQEEAEKLAADLEKAEEDAERQKADNEQLAAELNRAQEEAKRLAADLERAQE 2113

Query: 956  YVTQLEAQLQEYKNNIENLNMNVE--ELNKMNLELIDKHVQKQQTQSPDYTEQYINEINK 1013
               +L A+L+  +   E L  ++E  E +    +  ++ +     +     E+   E  K
Sbjct: 2114 EAEKLAAELERAQEEAEKLAADLEKAEEDAERQKADNRRLAADNERLAAELERTQEEAEK 2173

Query: 1014 LNALLKQKDEEIIALNQKINNAQVSY-MSMVSDYESKLAQFTTKLENMEEEM----QRVS 1068
            L A L++ +EE  A  QK +N +++  +    +   KLA    K E   E      +R++
Sbjct: 2174 LAADLEKAEEE--AERQKADNERLAAELDRAQEEAEKLAADLEKAEEDAERQKADNERLA 2231

Query: 1069 KQLLDSKQHNEEL--QILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDAN 1126
             +L  +++  E+L   +   E+D + ++    +L  E+N  + E   +++ +E   ++A 
Sbjct: 2232 AELNRAQEEAEKLAADLEKAEEDAERQKADNERLAAELNRAQEEAERLAAELERAQEEAE 2291

Query: 1127 NVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKI----IQLETLN 1182
             +              K  + E+   E +  QE++ KL  EL++   +       LE   
Sbjct: 2292 KLAADLEKAEEEAERQKA-DNEQLAAELNRAQEEAEKLAAELEKAQEEAEKLAADLEKAE 2350

Query: 1183 TELTGHDVVNQE---QINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELW 1239
             E       N+    ++N+ + + E+L  E +        L + +  A ++     AEL 
Sbjct: 2351 EEAERQKADNERLAAELNRAQEEAEKLAAELEKAQEEAERLAAELEKAQEEAERLAAELN 2410

Query: 1240 K-QHLAQR-EADFQKTEHE---LRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTS 1294
            + Q  A+R  A+ ++ + E   L  +L   + + E+L   ++ + QEE  ++    ++  
Sbjct: 2411 RAQEEAERLAAELERAQEEAERLAAELDRAQEEAERLAAELERA-QEEAERLAA--ELNR 2467

Query: 1295 LQNKLQDKEEHLRNLQEKYADVINQIEILRSEIE---DEKVAFXXXXXXXXXXXXXXXXD 1351
             Q + +    +L   QE+        E L +E+E   +E                    +
Sbjct: 2468 AQEEAEKLAANLEKAQEEAERQKAHNERLAAELERAREEAERLAAELEKAQEEAERLAAE 2527

Query: 1352 LRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLEL 1411
            L    +  +++  + +    EE  +L                 ++ A+ +  +L   LE 
Sbjct: 2528 LEKAREEAERLAAE-LERAREEAERLAAELEKAQEEAERLAAELDRAQEEAEKLAADLEK 2586

Query: 1412 KDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENAN 1471
             + E  ++  +    L    D  +   ++L    +R ++      +EL   + +    A 
Sbjct: 2587 AEEEAERQKADNE-RLAAELDRAQEEAERLAAELERAQEEAERLAAELDRAQEEAERLAA 2645

Query: 1472 HYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQE 1530
              +  Q+E+E     L +       +     +  AELN+A EE      E++ A E  E
Sbjct: 2646 ELDRAQEEAEKLAADLEKAEEEAERQKADNERLAAELNRAQEEAERLAAELEKAQEEAE 2704



 Score =  121 bits (291), Expect = 2e-25
 Identities = 241/1373 (17%), Positives = 533/1373 (38%), Gaps = 78/1373 (5%)

Query: 217  QMTKMQENFIAMEAEW---KDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSK 273
            ++ + QE    + AE    ++E ++L  D+E  +      +  N+ L A       E  +
Sbjct: 854  ELERAQEEAEKLAAELDRAQEEAEKLAADLEKAEEEAEKQKAHNERLAAELERAQEEAER 913

Query: 274  LAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEH 333
            LA EL++                +++     E +    +   L      EL +  E  E 
Sbjct: 914  LAAELDRALEEAEKLAADLEKAEEEAERQKAENRRLAADNERL----AAELDRAQEEAEK 969

Query: 334  LNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISR-KSGRNTASKMKSPWSQLSSE 392
            L   + +  +E E + A     +  +    ++   L +     +  A K+ +   +   +
Sbjct: 970  LAADLEKAEEEAERQKAENRRLAAELERAQEEAERLAAELDRAQEEAEKLAADLEKAEEK 1029

Query: 393  TLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEK---DTXXXXXXXXXXGKDTLI 449
               Q  + +    E+ + +   + L  +L D+    +EK   D             +   
Sbjct: 1030 AERQKAENRRLAAELERAQEEAERLAAEL-DRAQEEAEKLAADLEKAEEEAERQKAENRR 1088

Query: 450  AQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAE 509
               +LE  Q         +    E+  ++A   E+ ++E   E +    + L  +L+ A+
Sbjct: 1089 LAAELERAQEEAERLAAELDRAQEEAEKLAADLEKAEEEA--ERQKAENRRLAAELERAQ 1146

Query: 510  EQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNK----EIVRLTEELH 565
            E+  +L  E++ A +   ++ +      ++ +K      +  +  +    E+ R  EE  
Sbjct: 1147 EEAERLAAELERAQEEAERLAAELDRAQEEAEKLAAELERAQEEAEKLAAELDRAQEEAE 1206

Query: 566  HLSQKVAELEEEKGNLQLHL-VDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKF 624
             L+ ++ + +EE   L   L    +    + +++ K   E E LA    KA    E QK 
Sbjct: 1207 RLAAELEKAQEEAERLAAELEKTQEEAERLAAELEKAQEEAERLAADLEKAEEDAERQKA 1266

Query: 625  DLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIEN 684
            +  +    + +  +E E   AD+ + + D    +  +  L  +++      + LA  +E 
Sbjct: 1267 EKERLAAEVDRAQEEAEKLAADLEKAEEDAERQKADNERLAAELNRAQEEAERLAADLEK 1326

Query: 685  LKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKM--SAEKISELLAKINHE 742
             + D E+     + L  D E +  +L+   +E   L  +L++    AE+++  L K   +
Sbjct: 1327 AEEDAERQKADNRRLAADNERLAAELERAQEEAERLAAELDRAQEEAERLAADLEKAEED 1386

Query: 743  EQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLE---ESIAVMEDR-RYSLER- 797
             + +      + A++       E + ++L K +    R +   E +A   +R    L+R 
Sbjct: 1387 AERQKADNERLAAELDRAQEEAEKLAADLEKAEEDAERQKADNERLAADNERLAAELDRA 1446

Query: 798  --KADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKN 855
              +A++L + L++ ++         + L   L    +    +  +L + + E + L  + 
Sbjct: 1447 QEEAERLAADLEKAEEDAERQKADNERLAAELDRAQEEAERLAAELEKAQEEAERLAAEL 1506

Query: 856  QILLEENQNLQISLSDMQQHYNALVEKANR--TDL--AESESTKYQTQLRDLESNLKRIT 911
            +   EE +  +     +    +   E+A +   DL  AE ++ + +     L + L R  
Sbjct: 1507 EKAQEEAERQKADKERLAAELDRAQEEAEKLAADLEKAEEDAERQKADNERLAAELNRAQ 1566

Query: 912  HEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNI 971
             E + L    +K  ED E +          D + L  + E+  E   +L A+L++ +   
Sbjct: 1567 EEAERLAADLEKAEEDAERQ-KADNRRLAADNERLAAELERAQEEAERLAAELEKAQEEA 1625

Query: 972  ENLNMNVEELNKMNLELIDKHVQK---QQTQSPDYTEQYINEINKLNALLKQKDEEIIAL 1028
            E    + E L    L+   +  +K      ++ +  E+   E  +L A L++  EE   L
Sbjct: 1626 ERQKADKERL-AAELDRAQEEAEKLAADLEKAEEEAERQKAENRRLAAELERAQEEAERL 1684

Query: 1029 NQKINNAQVSYMSMVSDYE-SKLAQFTTKLEN--MEEEMQRVSKQLLDSKQHNEEL--QI 1083
              +++ AQ     + +D E ++      K +N  +  + +R++ +L  +++  E L   +
Sbjct: 1685 AAELDRAQEEAEKLAADLEKAEEDAERQKADNRRLAADNERLAAELDRAQEEAERLAADL 1744

Query: 1084 LVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLK 1143
               E+D + ++    +L  E++  + E   +++ +E   ++A  +              K
Sbjct: 1745 EKAEEDAERQKADNERLAAELDRAQEEAERLAAELEKAQEEAERLAAELEKAQEEAERQK 1804

Query: 1144 VQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKL 1203
              ++E    E    QE++ KL  +L++   +  + +  N  L   +     ++ + + + 
Sbjct: 1805 A-DKERLAAELDRAQEEAEKLAADLEKAEEEAERQKADNRRLAADNERLAAELERAQEEA 1863

Query: 1204 EQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEH-------- 1255
            E+L  E +        L + +  A ++     A+L K   A+ EA+ QK ++        
Sbjct: 1864 ERLAAELERAQEEAERLAAEVDRAQEEAEQLAADLEK---AEEEAERQKADNRRLAADNE 1920

Query: 1256 ELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKL-------QDKEEHLRN 1308
             L  +L   + + E+L   ++ + +E       +E+      +L       ++  E  + 
Sbjct: 1921 RLAAELDRAQEEAERLAAELEKAEEEAERLAAELEKAQEEAERLAADLEKAEEDAERQKA 1980

Query: 1309 LQEKYADVINQ---------IEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSY 1359
              E+ A  +N+          ++ R++ E EK+A                 +   E+   
Sbjct: 1981 DNEQLAAELNRAQEEAKRLAADLERAQEEAEKLAAELERAQEEAEKLAADLEKAEEDAER 2040

Query: 1360 KQMQEQSILNINEE-NAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQ 1418
            ++   + +   NE   A+L+++                DAE +  +   QL  + +   +
Sbjct: 2041 QKADNERLAADNERLAAELERTQEEAEKLAADLEKAEEDAERQKAD-NEQLAAELNRAQE 2099

Query: 1419 KTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKE-SELAILRLKMHENANHYETMQ 1477
            +       L +  +E E +  +L   ++  E L  + E +E    R K        +  +
Sbjct: 2100 EAKRLAADLERAQEEAEKLAAELERAQEEAEKLAADLEKAEEDAERQKADNRRLAADNER 2159

Query: 1478 KESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQE 1530
              +E+ER +  EE   K+   +   ++ AE  KA  E +A   E+  A E  E
Sbjct: 2160 LAAELERTQ--EEAE-KLAADLEKAEEEAERQKADNERLAA--ELDRAQEEAE 2207



 Score =  120 bits (290), Expect = 3e-25
 Identities = 260/1375 (18%), Positives = 532/1375 (38%), Gaps = 89/1375 (6%)

Query: 217  QMTKMQENFIAMEAEW---KDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSK 273
            ++ + QE    + AE    ++E ++L  D+E  + +    +  N+ L A       E  +
Sbjct: 994  ELERAQEEAERLAAELDRAQEEAEKLAADLEKAEEKAERQKAENRRLAAELERAQEEAER 1053

Query: 274  LAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEK---TEIEEKGSLEIANMTELTKKIEL 330
            LA EL++                +++     E +    E+E           EL +  E 
Sbjct: 1054 LAAELDRAQEEAEKLAADLEKAEEEAERQKAENRRLAAELERAQEEAERLAAELDRAQEE 1113

Query: 331  LEHLNCQIRQTNKELENKLA---TMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWS 387
             E L   + +  +E E + A    +  E +     +++ +  + R          +   +
Sbjct: 1114 AEKLAADLEKAEEEAERQKAENRRLAAELERAQEEAERLAAELERAQEEAERLAAELDRA 1173

Query: 388  QLSSETLNQDTDKKINKNE--IAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGK 445
            Q  +E L  + ++   + E   A+L+   +   +   + E    E +             
Sbjct: 1174 QEEAEKLAAELERAQEEAEKLAAELDRAQEEAERLAAELEKAQEEAERLAAELEKTQEEA 1233

Query: 446  DTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEI--KDVNVKDLIE 503
            + L A+L+ + Q+  E      +  + E   E A+ Q+  K+ L  E+       + L  
Sbjct: 1234 ERLAAELE-KAQEEAE-----RLAADLEKAEEDAERQKAEKERLAAEVDRAQEEAEKLAA 1287

Query: 504  KLKSAEEQI-------TQLNDEIDAANKNMIKVKSN-HKLKLKQMQKTIDNFSKVSDSNK 555
             L+ AEE          +L  E++ A +   ++ ++  K +    ++  DN    +D+ +
Sbjct: 1288 DLEKAEEDAERQKADNERLAAELNRAQEEAERLAADLEKAEEDAERQKADNRRLAADNER 1347

Query: 556  ---EIVRLTEELHHLSQKVAELEEEKGNL--QLHLVDYDSGRM------IESDVYKKMIE 604
               E+ R  EE   L+ ++   +EE   L   L   + D+ R       + +++ +   E
Sbjct: 1348 LAAELERAQEEAERLAAELDRAQEEAERLAADLEKAEEDAERQKADNERLAAELDRAQEE 1407

Query: 605  MENLAETRLKAISLLESQKFD---LVQELHILQQKYD----EVEDKLADISQLQSDQVCS 657
             E LA    KA    E QK D   L  +   L  + D    E E   AD+ + + D    
Sbjct: 1408 AEKLAADLEKAEEDAERQKADNERLAADNERLAAELDRAQEEAERLAADLEKAEEDAERQ 1467

Query: 658  EIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQEN 717
            +  +  L  ++D      + LA  +E  + + E+L   ++  + + E      +    E 
Sbjct: 1468 KADNERLAAELDRAQEEAERLAAELEKAQEEAERLAAELEKAQEEAERQKADKERLAAEL 1527

Query: 718  MDLTDKLEKMSAE-KISELLAKINHEEQSKIQTQFGIDAKIQER-DLYIENIESELSKYK 775
                ++ EK++A+ + +E  A+    +  ++  +     +  ER    +E  E +  + K
Sbjct: 1528 DRAQEEAEKLAADLEKAEEDAERQKADNERLAAELNRAQEEAERLAADLEKAEEDAERQK 1587

Query: 776  SRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDH-D 834
            +   RL    A  E     LER  ++      E +KA  E   Q+ +   RLA  +D   
Sbjct: 1588 ADNRRL---AADNERLAAELERAQEEAERLAAELEKAQEEAERQKAD-KERLAAELDRAQ 1643

Query: 835  RVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESEST 894
               EK   ++E   +E +++      EN+ L   L   Q+    L   A   D A+ E+ 
Sbjct: 1644 EEAEKLAADLEKAEEEAERQK----AENRRLAAELERAQEEAERL---AAELDRAQEEAE 1696

Query: 895  KYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNI 954
            K    L   E + +R   +++ L    ++   +L+     + E    D +   E  E+  
Sbjct: 1697 KLAADLEKAEEDAERQKADNRRLAADNERLAAELD-RAQEEAERLAADLEKAEEDAERQK 1755

Query: 955  EYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKL 1014
                +L A+L   +   E L   +E+  +   E +   ++K Q ++    E+   +  +L
Sbjct: 1756 ADNERLAAELDRAQEEAERLAAELEKAQE-EAERLAAELEKAQEEA----ERQKADKERL 1810

Query: 1015 NALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLA---QFTTKLENMEEEMQRVSKQL 1071
             A L +  EE   L   +  A+       +D     A   +   +LE  +EE +R++ +L
Sbjct: 1811 AAELDRAQEEAEKLAADLEKAEEEAERQKADNRRLAADNERLAAELERAQEEAERLAAEL 1870

Query: 1072 LDSKQHNEELQILVREQDDQIKELKE--TKLTFEMNIPKTEGMIISSTIEPMSDDANNVD 1129
              +++  E L   V    ++ ++L     K   E    K +   +++  E ++ + +   
Sbjct: 1871 ERAQEEAERLAAEVDRAQEEAEQLAADLEKAEEEAERQKADNRRLAADNERLAAELDRAQ 1930

Query: 1130 XXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHD 1189
                         + +E E    E    QE++ +L  +L++      + +  N +L    
Sbjct: 1931 EEAERLAAELEKAE-EEAERLAAELEKAQEEAERLAADLEKAEEDAERQKADNEQLAAEL 1989

Query: 1190 VVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISS-AVD-QRGFEIAELWKQHLAQRE 1247
               QE+  +L + LE+   E + L + +   +      A D ++  E AE  K    +  
Sbjct: 1990 NRAQEEAKRLAADLERAQEEAEKLAAELERAQEEAEKLAADLEKAEEDAERQKADNERLA 2049

Query: 1248 ADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLR 1307
            AD ++    L  +L   + + E+L   ++ + ++   +    EQ+ +  N+ Q++ + L 
Sbjct: 2050 ADNER----LAAELERTQEEAEKLAADLEKAEEDAERQKADNEQLAAELNRAQEEAKRLA 2105

Query: 1308 NLQEKYADVINQI--EILRSEIEDEKVAF-XXXXXXXXXXXXXXXXDLRTENQSYKQMQE 1364
               E+  +   ++  E+ R++ E EK+A                   L  +N+      E
Sbjct: 2106 ADLERAQEEAEKLAAELERAQEEAEKLAADLEKAEEDAERQKADNRRLAADNERLAAELE 2165

Query: 1365 QSILNINEENAQLKKS---SXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTH 1421
            ++     +  A L+K+   +             ++ A+ +  +L   LE  + +  ++  
Sbjct: 2166 RTQEEAEKLAADLEKAEEEAERQKADNERLAAELDRAQEEAEKLAADLEKAEEDAERQKA 2225

Query: 1422 EYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEK--ESELAILRLKMHENANHYETMQKE 1479
            +      + N   E   +   + EK  ED   +K     LA    +  E A       + 
Sbjct: 2226 DNERLAAELNRAQEEAEKLAADLEKAEEDAERQKADNERLAAELNRAQEEAERLAAELER 2285

Query: 1480 SEIERVKL---IEELNVKITESVSLNKQV-AELNKALEEEVAKTNEMQTALENQE 1530
            ++ E  KL   +E+   +     + N+Q+ AELN+A EE      E++ A E  E
Sbjct: 2286 AQEEAEKLAADLEKAEEEAERQKADNEQLAAELNRAQEEAEKLAAELEKAQEEAE 2340



 Score =  116 bits (279), Expect = 5e-24
 Identities = 258/1377 (18%), Positives = 528/1377 (38%), Gaps = 84/1377 (6%)

Query: 233  KDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXX 292
            ++E ++L  D+E  +      +  N+ L A       E  +LA EL++            
Sbjct: 964  QEEAEKLAADLEKAEEEAERQKAENRRLAAELERAQEEAERLAAELDRAQEEAEKLAADL 1023

Query: 293  XXLAKQSIEPSCEEK---TEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKL 349
                +++     E +    E+E           EL +  E  E L   + +  +E E + 
Sbjct: 1024 EKAEEKAERQKAENRRLAAELERAQEEAERLAAELDRAQEEAEKLAADLEKAEEEAERQK 1083

Query: 350  ATMGTESKAVSSPSKKGSPLISR-KSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIA 408
            A     +  +    ++   L +     +  A K+ +   +   E   Q   K  N+   A
Sbjct: 1084 AENRRLAAELERAQEEAERLAAELDRAQEEAEKLAADLEKAEEEAERQ---KAENRRLAA 1140

Query: 409  KLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQ-LEHQQHMEGPSLIH 467
            +LE   +   +   + E    E +             + L A+L+  + +       L  
Sbjct: 1141 ELERAQEEAERLAAELERAQEEAERLAAELDRAQEEAEKLAAELERAQEEAEKLAAELDR 1200

Query: 468  VGTNTEDV-NEIAKVQEQLKQELND-EIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKN 525
                 E +  E+ K QE+ ++   + E      + L  +L+ A+E+  +L  +++ A ++
Sbjct: 1201 AQEEAERLAAELEKAQEEAERLAAELEKTQEEAERLAAELEKAQEEAERLAADLEKAEED 1260

Query: 526  MIKVKSNHKLKLKQMQKTIDNFSKV-SDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLH 584
              + K+  +    ++ +  +   K+ +D  K       +     +  AEL   +   +  
Sbjct: 1261 AERQKAEKERLAAEVDRAQEEAEKLAADLEKAEEDAERQKADNERLAAELNRAQEEAERL 1320

Query: 585  LVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKL 644
              D +     E D  ++  +   LA    +  + LE  + +  +    L +  +E E   
Sbjct: 1321 AADLEKA---EEDAERQKADNRRLAADNERLAAELERAQEEAERLAAELDRAQEEAERLA 1377

Query: 645  ADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKE 704
            AD+ + + D    +  +  L  ++D      ++LA  +E  + D E+     + L  D E
Sbjct: 1378 ADLEKAEEDAERQKADNERLAAELDRAQEEAEKLAADLEKAEEDAERQKADNERLAADNE 1437

Query: 705  DIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYI 764
             +  +L    +E   L   LEK  AE+ +E   K ++E  +       +D   +E +   
Sbjct: 1438 RLAAELDRAQEEAERLAADLEK--AEEDAE-RQKADNERLAA-----ELDRAQEEAERLA 1489

Query: 765  ENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELV 824
              +E    + +     LE++    E ++   ER A +L    +E +K  ++    E++  
Sbjct: 1490 AELEKAQEEAERLAAELEKAQEEAERQKADKERLAAELDRAQEEAEKLAADLEKAEEDAE 1549

Query: 825  NRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKAN 884
             + A   D++R+      E+    +E ++    L +  ++ +   +D ++        A 
Sbjct: 1550 RQKA---DNERLA----AELNRAQEEAERLAADLEKAEEDAERQKADNRRLAADNERLAA 1602

Query: 885  RTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKK 944
              + A+ E+ +   +L   +   +R   + + L  +  +  E+ E +    +E A  +++
Sbjct: 1603 ELERAQEEAERLAAELEKAQEEAERQKADKERLAAELDRAQEEAE-KLAADLEKA--EEE 1659

Query: 945  VLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYT 1004
               +K E N     +LE   +E +     L+   EE  K+  +L +K  +  + Q  D  
Sbjct: 1660 AERQKAE-NRRLAAELERAQEEAERLAAELDRAQEEAEKLAADL-EKAEEDAERQKAD-N 1716

Query: 1005 EQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEM 1064
             +   +  +L A L +  EE   L   +  A+       +D E    +   +L+  +EE 
Sbjct: 1717 RRLAADNERLAAELDRAQEEAERLAADLEKAEEDAERQKADNE----RLAAELDRAQEEA 1772

Query: 1065 QRVSKQLLDSKQHNEELQILVREQDDQIKELKETK--LTFEMNIPKTEGMIISSTIEPMS 1122
            +R++ +L  +++  E L   + +  ++ +  K  K  L  E++  + E   +++ +E   
Sbjct: 1773 ERLAAELEKAQEEAERLAAELEKAQEEAERQKADKERLAAELDRAQEEAEKLAADLEKAE 1832

Query: 1123 DDANNVDXXXXXXXXXXXXL-----KVQEE-EEFIQERSVLQEQSAKLNTELQECYTKII 1176
            ++A                L     + QEE E    E    QE++ +L  E+     +  
Sbjct: 1833 EEAERQKADNRRLAADNERLAAELERAQEEAERLAAELERAQEEAERLAAEVDRAQEEAE 1892

Query: 1177 QLETLNTELTGHDVVNQEQIN-QLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEI 1235
            QL   + E    +   Q+  N +L +  E+L  E D        L + +  A ++     
Sbjct: 1893 QL-AADLEKAEEEAERQKADNRRLAADNERLAAELDRAQEEAERLAAELEKAEEEAERLA 1951

Query: 1236 AELWK-QHLAQR-EADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVT 1293
            AEL K Q  A+R  AD +K E +   Q    ++  EQL   +  + +E       +E+  
Sbjct: 1952 AELEKAQEEAERLAADLEKAEEDAERQ----KADNEQLAAELNRAQEEAKRLAADLERAQ 2007

Query: 1294 SLQNKLQDKEEHLRNLQEKYADVINQIE--ILRSEIEDEKVAFXXXXXXXXXXXXXXXXD 1351
                KL  + E  +   EK A  + + E    R + ++E++A                  
Sbjct: 2008 EEAEKLAAELERAQEEAEKLAADLEKAEEDAERQKADNERLAADNERLAAELE------- 2060

Query: 1352 LRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLEL 1411
             RT+ ++ K   +   L   EE+A+ +K+              +N A+ +   L   LE 
Sbjct: 2061 -RTQEEAEKLAAD---LEKAEEDAERQKAD------NEQLAAELNRAQEEAKRLAADLER 2110

Query: 1412 KDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENAN 1471
               E  +   E    L +  +E E +   L   EK  ED   +K ++   L       A 
Sbjct: 2111 AQEEAEKLAAE----LERAQEEAEKLAADL---EKAEEDAERQK-ADNRRLAADNERLAA 2162

Query: 1472 HYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEI 1531
              E  Q+E+E     L +       +     +  AEL++A EE      +++ A E+ E 
Sbjct: 2163 ELERTQEEAEKLAADLEKAEEEAERQKADNERLAAELDRAQEEAEKLAADLEKAEEDAER 2222

Query: 1532 EIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAE 1588
            +    N+ +    N  +  + K+   +  A +  + R +  +  +  EL  A   AE
Sbjct: 2223 QKAD-NERLAAELNRAQEEAEKLAADLEKAEEDAE-RQKADNERLAAELNRAQEEAE 2277



 Score =  112 bits (270), Expect = 7e-23
 Identities = 257/1374 (18%), Positives = 542/1374 (39%), Gaps = 105/1374 (7%)

Query: 233  KDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXX 292
            K + +RL  D E     +   +E  + L A       E  KLA +LE+            
Sbjct: 838  KADNRRLAADNERLAAELERAQEEAEKLAAELDRAQEEAEKLAADLEKAEEEAEKQKAHN 897

Query: 293  XXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATM 352
              LA + +E + EE   +            EL + +E  E L   + +  +E E + A  
Sbjct: 898  ERLAAE-LERAQEEAERL----------AAELDRALEEAEKLAADLEKAEEEAERQKA-- 944

Query: 353  GTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEM 412
              E++ +++ +++ +  + R   +  A K+ +   +   E   Q  + +    E+ + + 
Sbjct: 945  --ENRRLAADNERLAAELDR--AQEEAEKLAADLEKAEEEAERQKAENRRLAAELERAQE 1000

Query: 413  VIQSLNKDLVDKEYVISEK---DTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVG 469
              + L  +L D+    +EK   D             +      +LE  Q         + 
Sbjct: 1001 EAERLAAEL-DRAQEEAEKLAADLEKAEEKAERQKAENRRLAAELERAQEEAERLAAELD 1059

Query: 470  TNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKV 529
               E+  ++A   E+ ++E   E +    + L  +L+ A+E+  +L  E+D A +   K+
Sbjct: 1060 RAQEEAEKLAADLEKAEEEA--ERQKAENRRLAAELERAQEEAERLAAELDRAQEEAEKL 1117

Query: 530  KSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYD 589
             ++ +   ++ ++      +++    E+ R  EE   L+ ++   +EE   L   L    
Sbjct: 1118 AADLEKAEEEAERQKAENRRLA---AELERAQEEAERLAAELERAQEEAERLAAEL---- 1170

Query: 590  SGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADI-- 647
                 + +  K   E+E   E   K  + L+  + +  +    L++  +E E   A++  
Sbjct: 1171 --DRAQEEAEKLAAELERAQEEAEKLAAELDRAQEEAERLAAELEKAQEEAERLAAELEK 1228

Query: 648  SQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIM 707
            +Q +++++ +E++    +E+ + L+A  ++     E  K +KE+L   +   + + E + 
Sbjct: 1229 TQEEAERLAAELEKA--QEEAERLAADLEKAEEDAERQKAEKERLAAEVDRAQEEAEKLA 1286

Query: 708  NKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENI 767
              L+          +  E+  A+    L A++N  ++     +   D +  E D   +  
Sbjct: 1287 ADLEK-------AEEDAERQKADN-ERLAAELNRAQEE--AERLAADLEKAEEDAERQKA 1336

Query: 768  ES-ELSKYKSRI-CRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVN 825
            ++  L+    R+   LE +    E     L+R  ++      + +KA  +   Q+ +   
Sbjct: 1337 DNRRLAADNERLAAELERAQEEAERLAAELDRAQEEAERLAADLEKAEEDAERQKAD-NE 1395

Query: 826  RLAVLMDHDRVVEKQL---LEIEHENKELQK-KNQILLEENQNLQISLSDMQQHYNALVE 881
            RLA  +D  +   ++L   LE   E+ E QK  N+ L  +N+ L   L   Q+    L  
Sbjct: 1396 RLAAELDRAQEEAEKLAADLEKAEEDAERQKADNERLAADNERLAAELDRAQEEAERL-- 1453

Query: 882  KANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKK---EIEDLEIEFNTQIES 938
             A   + AE ++ + +     L + L R   E + L  + +K   E E L  E     E 
Sbjct: 1454 -AADLEKAEEDAERQKADNERLAAELDRAQEEAERLAAELEKAQEEAERLAAELEKAQEE 1512

Query: 939  AIR---DKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVE----ELNKMNLEL--- 988
            A R   DK+ L  + ++  E   +L A L++ + + E    + E    ELN+   E    
Sbjct: 1513 AERQKADKERLAAELDRAQEEAEKLAADLEKAEEDAERQKADNERLAAELNRAQEEAERL 1572

Query: 989  ---IDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSD 1045
               ++K  +  + Q  D   +   +  +L A L++  EE   L  ++  AQ       +D
Sbjct: 1573 AADLEKAEEDAERQKAD-NRRLAADNERLAAELERAQEEAERLAAELEKAQEEAERQKAD 1631

Query: 1046 YESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKE--TKLTFE 1103
             E    +   +L+  +EE ++++  L  +++  E  +   R    +++  +E   +L  E
Sbjct: 1632 KE----RLAAELDRAQEEAEKLAADLEKAEEEAERQKAENRRLAAELERAQEEAERLAAE 1687

Query: 1104 MNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAK 1163
            ++  + E   +++ +E   +DA                    + E    E    QE++ +
Sbjct: 1688 LDRAQEEAEKLAADLEKAEEDAERQKADNRRLAA--------DNERLAAELDRAQEEAER 1739

Query: 1164 LNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSS 1223
            L  +L++      + +  N  L       QE+  +L ++LE+   E + L + + + +  
Sbjct: 1740 LAADLEKAEEDAERQKADNERLAAELDRAQEEAERLAAELEKAQEEAERLAAELEKAQEE 1799

Query: 1224 ISSAVDQRGFEIAELWK-QHLAQR-EADFQKTEHELRVQLS---AFESKYEQLLDSVQSS 1278
                   +    AEL + Q  A++  AD +K E E   Q +      +  E+L   ++ +
Sbjct: 1800 AERQKADKERLAAELDRAQEEAEKLAADLEKAEEEAERQKADNRRLAADNERLAAELERA 1859

Query: 1279 TQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXX 1338
             QEE  ++    ++   Q + +     +   QE+   +   +E    E E +K A     
Sbjct: 1860 -QEEAERLAA--ELERAQEEAERLAAEVDRAQEEAEQLAADLEKAEEEAERQK-ADNRRL 1915

Query: 1339 XXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDA 1398
                          + E +      E++        A+L+K+                DA
Sbjct: 1916 AADNERLAAELDRAQEEAERLAAELEKAEEEAERLAAELEKAQEEAERLAADLEKAEEDA 1975

Query: 1399 EAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKE-S 1457
            E +  +   QL  + +   ++       L +  +E E +  +L   ++  E L  + E +
Sbjct: 1976 ERQKAD-NEQLAAELNRAQEEAKRLAADLERAQEEAEKLAAELERAQEEAEKLAADLEKA 2034

Query: 1458 ELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEV- 1516
            E    R K        +  +  +E+ER +  EE   K+   +   ++ AE  KA  E++ 
Sbjct: 2035 EEDAERQKADNERLAADNERLAAELERTQ--EEAE-KLAADLEKAEEDAERQKADNEQLA 2091

Query: 1517 AKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDE 1570
            A+ N  Q   +    ++    +E   L   +  +  + +K    A+D ++  ++
Sbjct: 2092 AELNRAQEEAKRLAADLERAQEEAEKLAAELERAQEEAEK---LAADLEKAEED 2142



 Score =  105 bits (251), Expect = 1e-20
 Identities = 213/1157 (18%), Positives = 471/1157 (40%), Gaps = 84/1157 (7%)

Query: 469  GTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIK 528
            GT    + E  +  E+ K + N  +   N + L  +L+ A+E+  +L  E+D A +   K
Sbjct: 821  GTLARQLQEAQQDAERQKAD-NRRLAADNER-LAAELERAQEEAEKLAAELDRAQEEAEK 878

Query: 529  VKSNHKLKLKQMQKTIDN----FSKVSDSNKEIVRLTEELHHLSQKV---------AELE 575
            + ++ +   ++ +K   +     +++  + +E  RL  EL    ++          AE E
Sbjct: 879  LAADLEKAEEEAEKQKAHNERLAAELERAQEEAERLAAELDRALEEAEKLAADLEKAEEE 938

Query: 576  EEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFD---LVQELHI 632
             E+   +   +  D+ R + +++ +   E E LA    KA    E QK +   L  EL  
Sbjct: 939  AERQKAENRRLAADNER-LAAELDRAQEEAEKLAADLEKAEEEAERQKAENRRLAAELER 997

Query: 633  LQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQL 692
             Q++ + +  +L D +Q +++++ ++++    EE+ +   A  + LA  +E  + + E+L
Sbjct: 998  AQEEAERLAAEL-DRAQEEAEKLAADLEKA--EEKAERQKAENRRLAAELERAQEEAERL 1054

Query: 693  YGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFG 752
               +   + + E +   L+   +E        E+  AE    L A++   ++   +    
Sbjct: 1055 AAELDRAQEEAEKLAADLEKAEEE-------AERQKAEN-RRLAAELERAQEEAERLAAE 1106

Query: 753  IDAKIQERDLY---IENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEK 809
            +D   +E +     +E  E E  + K+   RL    A +E  +   ER A +L    +E 
Sbjct: 1107 LDRAQEEAEKLAADLEKAEEEAERQKAENRRL---AAELERAQEEAERLAAELERAQEEA 1163

Query: 810  QKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISL 869
            ++  +E    ++E     A L       EK   E++   +E ++    L +  +  +   
Sbjct: 1164 ERLAAELDRAQEEAEKLAAELERAQEEAEKLAAELDRAQEEAERLAAELEKAQEEAERLA 1223

Query: 870  SDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLE 929
            +++++        A   + A+ E+ +    L   E + +R   E + L  +  +  E+ E
Sbjct: 1224 AELEKTQEEAERLAAELEKAQEEAERLAADLEKAEEDAERQKAEKERLAAEVDRAQEEAE 1283

Query: 930  IEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELI 989
             +    +E A  D +   +K + N     +L    +E +    +L    E+  +   +  
Sbjct: 1284 -KLAADLEKAEEDAE--RQKAD-NERLAAELNRAQEEAERLAADLEKAEEDAERQKAD-- 1337

Query: 990  DKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESK 1049
            ++ +     +     E+   E  +L A L +  EE   L   +  A+       +D E  
Sbjct: 1338 NRRLAADNERLAAELERAQEEAERLAAELDRAQEEAERLAADLEKAEEDAERQKADNE-- 1395

Query: 1050 LAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKT 1109
              +   +L+  +EE ++++  L  +++  E      ++ D++       +L  E++  + 
Sbjct: 1396 --RLAAELDRAQEEAEKLAADLEKAEEDAER-----QKADNERLAADNERLAAELDRAQE 1448

Query: 1110 EGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQ 1169
            E   +++ +E   +DA                 + +E E    E    QE++ +L  EL+
Sbjct: 1449 EAERLAADLEKAEEDAERQKADNERLAAELDRAQ-EEAERLAAELEKAQEEAERLAAELE 1507

Query: 1170 ECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVD 1229
            +   +  + +     L       QE+  +L + LE+   + +   +    L + ++ A +
Sbjct: 1508 KAQEEAERQKADKERLAAELDRAQEEAEKLAADLEKAEEDAERQKADNERLAAELNRAQE 1567

Query: 1230 QRGFEIAELWKQHLAQREADFQKTEH--------ELRVQLSAFESKYEQLLDSVQSSTQE 1281
            +     A+L K   A+ +A+ QK ++         L  +L   + + E+L   ++ + +E
Sbjct: 1568 EAERLAADLEK---AEEDAERQKADNRRLAADNERLAAELERAQEEAERLAAELEKAQEE 1624

Query: 1282 ETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXX 1341
               +    E++ +  ++ Q++ E L    EK  +     E  R + E+ ++A        
Sbjct: 1625 AERQKADKERLAAELDRAQEEAEKLAADLEKAEE-----EAERQKAENRRLAAELERAQE 1679

Query: 1342 XXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKS-SXXXXXXXXXXXXRVNDAEA 1400
                     D R + ++ K   +   L   EE+A+ +K+ +             ++ A+ 
Sbjct: 1680 EAERLAAELD-RAQEEAEKLAAD---LEKAEEDAERQKADNRRLAADNERLAAELDRAQE 1735

Query: 1401 KVLELTHQLEL--KDSEIYQKTHE-YTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKE- 1456
            +   L   LE   +D+E  +  +E     L +  +E E +  +L + ++  E L  E E 
Sbjct: 1736 EAERLAADLEKAEEDAERQKADNERLAAELDRAQEEAERLAAELEKAQEEAERLAAELEK 1795

Query: 1457 SELAILRLKMHENANHYETMQKESEIERVKL-IEELNVKITESVSLNKQVAELNKALEEE 1515
            ++    R K  +     E  + + E E++   +E+   +     + N+++A  N+ L  E
Sbjct: 1796 AQEEAERQKADKERLAAELDRAQEEAEKLAADLEKAEEEAERQKADNRRLAADNERLAAE 1855

Query: 1516 VAKTNE----MQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQ 1571
            + +  E    +   LE  + E   L  E+   Q      ++ ++K    A   +Q  D +
Sbjct: 1856 LERAQEEAERLAAELERAQEEAERLAAEVDRAQEEAEQLAADLEKAEEEAE--RQKADNR 1913

Query: 1572 LDNTMNKELLDAVPRAE 1588
                 N+ L   + RA+
Sbjct: 1914 RLAADNERLAAELDRAQ 1930



 Score = 97.5 bits (232), Expect = 3e-18
 Identities = 195/1033 (18%), Positives = 404/1033 (39%), Gaps = 75/1033 (7%)

Query: 564  LHHLSQKVAELEEEKGNLQLHLVDYDS-GRMIESDVYKKMIEMENLAETRLKAISLLESQ 622
            LHH  ++   L  +    Q       +  R + +D  +   E+E   E   K  + L+  
Sbjct: 813  LHHAEEEAGTLARQLQEAQQDAERQKADNRRLAADNERLAAELERAQEEAEKLAAELDRA 872

Query: 623  KFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVI 682
            + +  +    L++  +E E + A   +L ++   ++ ++  L  ++D      ++LA  +
Sbjct: 873  QEEAEKLAADLEKAEEEAEKQKAHNERLAAELERAQEEAERLAAELDRALEEAEKLAADL 932

Query: 683  ENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAE------KISELL 736
            E  + + E+     + L  D E +  +L    +E   L   LEK   E      +   L 
Sbjct: 933  EKAEEEAERQKAENRRLAADNERLAAELDRAQEEAEKLAADLEKAEEEAERQKAENRRLA 992

Query: 737  AKINHEEQSKIQTQFGIDAKIQERDLYIENIE-----SELSKYKSRICRLEESIAVMEDR 791
            A++   ++   +    +D   +E +    ++E     +E  K ++R    E   A  E  
Sbjct: 993  AELERAQEEAERLAAELDRAQEEAEKLAADLEKAEEKAERQKAENRRLAAELERAQEEAE 1052

Query: 792  RYSLE-----RKADQLGSYLQ------EKQKAYSEYTIQE----DELVNRLAVLMDH-DR 835
            R + E      +A++L + L+      E+QKA +     E     E   RLA  +D    
Sbjct: 1053 RLAAELDRAQEEAEKLAADLEKAEEEAERQKAENRRLAAELERAQEEAERLAAELDRAQE 1112

Query: 836  VVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRT-DLAE---S 891
              EK   ++E   +E +++      EN+ L   L   Q+    L  +  R  + AE   +
Sbjct: 1113 EAEKLAADLEKAEEEAERQK----AENRRLAAELERAQEEAERLAAELERAQEEAERLAA 1168

Query: 892  ESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYE 951
            E  + Q +   L + L+R   E + L  +  +  E+ E     ++E A  + + L  + E
Sbjct: 1169 ELDRAQEEAEKLAAELERAQEEAEKLAAELDRAQEEAE-RLAAELEKAQEEAERLAAELE 1227

Query: 952  KNIEYVTQLEAQLQEYKNNIENLNMNVE------ELNKMNLELIDKHVQKQQTQ------ 999
            K  E   +L A+L++ +   E L  ++E      E  K   E +   V + Q +      
Sbjct: 1228 KTQEEAERLAAELEKAQEEAERLAADLEKAEEDAERQKAEKERLAAEVDRAQEEAEKLAA 1287

Query: 1000 ----SPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLA---Q 1052
                + +  E+   +  +L A L +  EE   L   +  A+       +D     A   +
Sbjct: 1288 DLEKAEEDAERQKADNERLAAELNRAQEEAERLAADLEKAEEDAERQKADNRRLAADNER 1347

Query: 1053 FTTKLENMEEEMQRVSKQLLDSKQHNEEL--QILVREQDDQIKELKETKLTFEMNIPKTE 1110
               +LE  +EE +R++ +L  +++  E L   +   E+D + ++    +L  E++  + E
Sbjct: 1348 LAAELERAQEEAERLAAELDRAQEEAERLAADLEKAEEDAERQKADNERLAAELDRAQEE 1407

Query: 1111 GMIISSTIEPMSDDANNVDXXXXXXXXXXXXL-----KVQEE-EEFIQERSVLQEQSAKL 1164
               +++ +E   +DA                L     + QEE E    +    +E + + 
Sbjct: 1408 AEKLAADLEKAEEDAERQKADNERLAADNERLAAELDRAQEEAERLAADLEKAEEDAERQ 1467

Query: 1165 NTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSI 1224
              + +    ++ + +     L       QE+  +L ++LE+   E +   +    L + +
Sbjct: 1468 KADNERLAAELDRAQEEAERLAAELEKAQEEAERLAAELEKAQEEAERQKADKERLAAEL 1527

Query: 1225 SSAVDQRGFEIAELWKQHLAQREADFQKTEHE-LRVQLSAFESKYEQLLDSVQSSTQEET 1283
              A ++     A+L K   A+ +A+ QK ++E L  +L+  + + E+L   ++ + ++  
Sbjct: 1528 DRAQEEAEKLAADLEK---AEEDAERQKADNERLAAELNRAQEEAERLAADLEKAEEDAE 1584

Query: 1284 NKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVIN--QIEILRSEIEDEKVAFXXXXXXX 1341
             +     ++ +   +L  + E  +   E+ A  +   Q E  R + + E++A        
Sbjct: 1585 RQKADNRRLAADNERLAAELERAQEEAERLAAELEKAQEEAERQKADKERLAAELDRAQE 1644

Query: 1342 XXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAK 1401
                     + + E ++ +Q  E   L    E AQ +                   A+ +
Sbjct: 1645 EAEKLAADLE-KAEEEAERQKAENRRLAAELERAQEEAERLAAELDRAQEEAEKLAADLE 1703

Query: 1402 VLELTHQLELKDSEIYQKTHE-YTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKE---S 1457
              E   + +  D+      +E     L +  +E E +   L + E+  E    + E   +
Sbjct: 1704 KAEEDAERQKADNRRLAADNERLAAELDRAQEEAERLAADLEKAEEDAERQKADNERLAA 1763

Query: 1458 ELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVA 1517
            EL   + +    A   E  Q+E+E    +L +       +     +  AEL++A EE   
Sbjct: 1764 ELDRAQEEAERLAAELEKAQEEAERLAAELEKAQEEAERQKADKERLAAELDRAQEEAEK 1823

Query: 1518 KTNEMQTALENQE 1530
               +++ A E  E
Sbjct: 1824 LAADLEKAEEEAE 1836



 Score = 84.2 bits (199), Expect = 3e-14
 Identities = 196/1090 (17%), Positives = 422/1090 (38%), Gaps = 62/1090 (5%)

Query: 53   KFERAQKCLENAALVSKRIKEHRKATAELLGRPFVPGISESLANTLKQKEILMEKIKQYK 112
            + ERAQ+  E  A   +R +E  +  A  + R      +E LA  L++ E   E+ ++ K
Sbjct: 1855 ELERAQEEAERLAAELERAQEEAERLAAEVDR--AQEEAEQLAADLEKAE---EEAERQK 1909

Query: 113  ELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNALSVLQVKMKIMETTI 172
              ++R +    R                      L    +E +   + L+   +  E   
Sbjct: 1910 ADNRRLAADNERLAAELDRAQEEAERL----AAELEKAEEEAERLAAELEKAQEEAERLA 1965

Query: 173  LDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEW 232
             DL EK  E  +  +A N+                    E  +++  K+     A E E 
Sbjct: 1966 ADL-EKAEEDAERQKADNEQLAAELNRAQEEAKRLAADLERAQEEAEKL-----AAELER 2019

Query: 233  -KDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXX 291
             ++E ++L  D+E  +      +  N+ L A    ++ E  +  +E E+           
Sbjct: 2020 AQEEAEKLAADLEKAEEDAERQKADNERLAADNERLAAELERTQEEAEKLAADLEKAEED 2079

Query: 292  XXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLAT 351
                   + + + E     EE   L      +L +  E  E L  ++ +  +E E KLA 
Sbjct: 2080 AERQKADNEQLAAELNRAQEEAKRLA----ADLERAQEEAEKLAAELERAQEEAE-KLAA 2134

Query: 352  MGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKL- 410
               +++  +   K  +  ++  + R  A   ++   Q  +E L  D +K   + E  K  
Sbjct: 2135 DLEKAEEDAERQKADNRRLAADNERLAAELERT---QEEAEKLAADLEKAEEEAERQKAD 2191

Query: 411  -EMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVG 469
             E +   L++   + E + ++ +             + L A+L    ++  +  + +   
Sbjct: 2192 NERLAAELDRAQEEAEKLAADLEKAEEDAERQKADNERLAAELNRAQEEAEKLAADLEKA 2251

Query: 470  TNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKV 529
               ED        E+L  ELN   ++   + L  +L+ A+E+  +L  +++ A +   + 
Sbjct: 2252 E--EDAERQKADNERLAAELNRAQEEA--ERLAAELERAQEEAEKLAADLEKAEEEAERQ 2307

Query: 530  KSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYD 589
            K++++    ++ +  +   K++    E+ +  EE   L+  + + EEE    +      D
Sbjct: 2308 KADNEQLAAELNRAQEEAEKLA---AELEKAQEEAEKLAADLEKAEEEAERQKA-----D 2359

Query: 590  SGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQ 649
            + R+  +++ +   E E LA    KA    E    +L +     ++   E+     +  +
Sbjct: 2360 NERLA-AELNRAQEEAEKLAAELEKAQEEAERLAAELEKAQEEAERLAAELNRAQEEAER 2418

Query: 650  LQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNK 709
            L ++   ++ ++  L  ++D      + LA  +E  + + E+L   +   + + E +   
Sbjct: 2419 LAAELERAQEEAERLAAELDRAQEEAERLAAELERAQEEAERLAAELNRAQEEAEKLAAN 2478

Query: 710  LQNYIQENMDLTDKLEKMSAE--KISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENI 767
            L+   +E        E+++AE  +  E   ++  E +   +    + A++++     E +
Sbjct: 2479 LEKAQEEAERQKAHNERLAAELERAREEAERLAAELEKAQEEAERLAAELEKAREEAERL 2538

Query: 768  ESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVN-- 825
             +EL + +    RL    A +E  +   ER A +L    +E +K  ++    E+E     
Sbjct: 2539 AAELERAREEAERLA---AELEKAQEEAERLAAELDRAQEEAEKLAADLEKAEEEAERQK 2595

Query: 826  ----RLAVLMDH-DRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALV 880
                RLA  +D      E+   E+E   +E ++    L    +  +   +++ +      
Sbjct: 2596 ADNERLAAELDRAQEEAERLAAELERAQEEAERLAAELDRAQEEAERLAAELDRAQEEAE 2655

Query: 881  EKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKK---EIEDLEIEFNTQIE 937
            + A   + AE E+ + +     L + L R   E + L  + +K   E E L  +     E
Sbjct: 2656 KLAADLEKAEEEAERQKADNERLAAELNRAQEEAERLAAELEKAQEEAEKLAADLEKAEE 2715

Query: 938  SAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQ 997
             A R K         N     +L+   +E +     L+   EE  ++  EL D+  ++ +
Sbjct: 2716 DAERQKADNRRLAADNERLAAELDRAQEEAERLAAELDRAQEEAERLAAEL-DRAQEEAE 2774

Query: 998  TQSPDY--TEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTT 1055
              + D    E+        N  L   +E + A   +         + +   + +  +   
Sbjct: 2775 KLAADLEKAEEDAERQKADNRRLAADNERLAAELDRAQEEAERLAAELDRAQEEAEKLAA 2834

Query: 1056 KLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIIS 1115
             LE  EE+ +R   Q  D+++   + + L  E D   +E +  +L  E++  + E   ++
Sbjct: 2835 DLEKAEEDAER---QKADNRRLAADNERLAAELDRAQEEAE--RLAAELDRAQEEAERLA 2889

Query: 1116 STIEPMSDDA 1125
            + ++   +DA
Sbjct: 2890 AELDRAQEDA 2899



 Score = 36.7 bits (81), Expect = 5.3
 Identities = 92/550 (16%), Positives = 203/550 (36%), Gaps = 33/550 (6%)

Query: 53   KFERAQKCLENAALVSKRIKEHRKATAELLGRPFVPGISESLANTLKQKEILMEKIKQYK 112
            +  RAQ+  E  A   +R +E  +  A  L R      +E LA  L++ +   E++    
Sbjct: 2408 ELNRAQEEAERLAAELERAQEEAERLAAELDR--AQEEAERLAAELERAQEEAERLAAEL 2465

Query: 113  ELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNALSVLQVKMKIMETTI 172
              ++  +  +                        L    +E +   + L+   +  E   
Sbjct: 2466 NRAQEEAEKLAANLEKAQEEAERQKAHNERLAAELERAREEAERLAAELEKAQEEAERLA 2525

Query: 173  LDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEW 232
             +L EK  E+ + + A+ +                    E    ++ + QE    + A+ 
Sbjct: 2526 AEL-EKAREEAERLAAELERAREEAERLAAELEKAQEEAERLAAELDRAQEEAEKLAADL 2584

Query: 233  K---DEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXX 289
            +   +E +R   D E     +   +E  + L A       E  +LA EL++         
Sbjct: 2585 EKAEEEAERQKADNERLAAELDRAQEEAERLAAELERAQEEAERLAAELDRAQEEAERLA 2644

Query: 290  XXXXXLAKQSIEPSCEEKTEIEEKGSLEIAN----MTELTKKIELLEHLNCQIRQTNKEL 345
                  A++  E    +  + EE+   + A+      EL +  E  E L  ++ +  +E 
Sbjct: 2645 AELDR-AQEEAEKLAADLEKAEEEAERQKADNERLAAELNRAQEEAERLAAELEKAQEEA 2703

Query: 346  ENKLATMG----------TESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLN 395
            E   A +            +++ +++ +++ +  + R          +   +Q  +E L 
Sbjct: 2704 EKLAADLEKAEEDAERQKADNRRLAADNERLAAELDRAQEEAERLAAELDRAQEEAERLA 2763

Query: 396  QDTDKKINKNE--IAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQL- 452
             + D+   + E   A LE   +   +   D   + ++ +             + L A+L 
Sbjct: 2764 AELDRAQEEAEKLAADLEKAEEDAERQKADNRRLAADNERLAAELDRAQEEAERLAAELD 2823

Query: 453  QLEHQQHMEGPSLIHVGTNTE----DVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSA 508
            + + +       L     + E    D   +A   E+L  EL D  ++   + L  +L  A
Sbjct: 2824 RAQEEAEKLAADLEKAEEDAERQKADNRRLAADNERLAAEL-DRAQE-EAERLAAELDRA 2881

Query: 509  EEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLS 568
            +E+  +L  E+D A ++  + K++++    ++ +  ++  +    N+   RLT EL    
Sbjct: 2882 QEEAERLAAELDRAQEDAERQKADNRRLAAELDRAQEDAERQKADNR---RLTGELADKE 2938

Query: 569  QKVAELEEEK 578
            +++A   E++
Sbjct: 2939 RELAAFREKR 2948


>UniRef50_O96133 Cluster: Putative uncharacterized protein PFB0145c;
            n=1; Plasmodium falciparum 3D7|Rep: Putative
            uncharacterized protein PFB0145c - Plasmodium falciparum
            (isolate 3D7)
          Length = 1979

 Score =  131 bits (317), Expect = 1e-28
 Identities = 202/1096 (18%), Positives = 466/1096 (42%), Gaps = 73/1096 (6%)

Query: 503  EKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSK--VSDSNKEIVRL 560
            E     + +  +  ++ D+  K +I+ K   K K K      DN ++  ++++N      
Sbjct: 22   ESFNEEDNENNEKREKSDSWYKKIIETKGKSKTKYKNDNSLDDNINEDIINNNNNNNNDN 81

Query: 561  TEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMI----EMENLAETRLKAI 616
              + ++ +      +    N   +  D ++      ++ K +I    E+EN  +  LK+I
Sbjct: 82   NNDNNNDNNNDNNNDNNNDNNNENNNDNNNFNNYSDEISKNIIHKDNELENQLKDTLKSI 141

Query: 617  SLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKK 676
            S L ++  +   ++  L+++  EV+DK  D +  ++     + K   ++++ID L+  +K
Sbjct: 142  SSLSNKIVNYESKIEELEKELKEVKDKNIDNNDYENKL---KEKEDFVKQKIDMLN--EK 196

Query: 677  ELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELL 736
            E  L  + L ++K +     K +   +++I+ K + +     +  +K ++     I E++
Sbjct: 197  ENLLQEKELDINKRE-----KKINEKEKNIIKKEETFHNIEKEYLEKNKERETISI-EII 250

Query: 737  AKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLE 796
                H E+ KI+ +   +  ++  +  + + E+ L + K  +    E+I  + D     E
Sbjct: 251  DIKKHLEKLKIEIKEKKE-DLENLNKKLLSKENVLKELKGCVKEKNETINSLNDNIIEKE 309

Query: 797  RKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQ 856
            +K   L   L+EK K       QE E         + +R  EK+  E +   KEL+ +  
Sbjct: 310  KKYKLLEYELEEKNKQIDLLNKQEKEKEKEKEREKEKEREKEKEK-EYDTLIKELKDEKI 368

Query: 857  ILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQT 916
             +LE+  ++++   D+++  +  +   ++    ++   K   QL+  +  +K +    +T
Sbjct: 369  SILEKVHSIKVREMDIEKREHNFLHMEDQLKDLKNSFVKNNNQLKVYKCEIKNL----KT 424

Query: 917  LIVQKKKEIEDLEIEFNTQIESAI-----RDKKVL----NEKYE--------KNIEYVTQ 959
             + +K+KE++D+E     +I   I     ++K++L    N K E        K    +T+
Sbjct: 425  ELEKKEKELKDIENVSKEEINKLINQLNEKEKQILAFNKNHKEEIHGLKEELKESVKITK 484

Query: 960  LEAQ-LQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALL 1018
            +E Q LQE  +  +     ++E     +E I   + K++ +   Y   YI EIN LN  L
Sbjct: 485  IETQELQEMVDIKQKELDQLQEKYNAQIESISIELSKKEKEYNQYKNTYIEEINNLNEKL 544

Query: 1019 KQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHN 1078
            ++ ++E   L     N      + +      +    T++  ++ ++  +++Q+       
Sbjct: 545  EETNKEYTNLQNNYTNEINMLNNDIHMLNGNIKTMNTQISTLKNDVHLLNEQIDKLNNEK 604

Query: 1079 EELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXX 1138
              L   + E + QI +LKE K      I      I   T   M +  N +          
Sbjct: 605  GTLNSKISELNVQIMDLKEEKDFLNNQIVDLSNQIDLLT-RKMEEKENKMLEQENKYKQE 663

Query: 1139 XXXLK---------VQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQL-ETLNTELTGH 1188
               L+         +  +EE    +  L  + +++    +E   K+ +L +  +  +   
Sbjct: 664  MELLRGNIKSSENILNNDEEVCDLKRKLSLKESEMKMMKEEHDKKLAELKDDCDVRIREM 723

Query: 1189 DVVNQEQINQLKSKLE-QLNT---ENDNLLSTVAEL-RSSISSAVDQRGFEIAELWKQHL 1243
            +  N+++IN LK + E ++NT   +N++ ++T+ E     I++  ++   +I  + +++ 
Sbjct: 724  NEKNEDKINMLKEEYEDKINTLKEQNEDKINTLKEQNEDKINTLKEEYEHKINTMKEEYE 783

Query: 1244 AQREADFQKTEHELRVQLSAFESKYEQLLDSVQS--STQEETNKIVTMEQVTSLQNKLQD 1301
             +     ++ EH++       E K   + +  +   +T  E N+    +++ SL+ + ++
Sbjct: 784  HKINTLNEQNEHKINTLNEQNEHKINTMKEEYEDKMNTLNEQNE----DKMNSLKEEYEN 839

Query: 1302 KEEHLRNLQE-KYADVIN----QIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTEN 1356
            K   + +  E K  DV+N    +++ L+  ++++K  F                 L TE 
Sbjct: 840  KINQINSNNEIKIKDVVNEYIEEVDKLKVTLDEKKKQFDKEINYAHIKAHEKEQILLTEM 899

Query: 1357 QSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEI 1416
            +  K  ++    ++ E+  +L KS                D   ++ E  +  +    E+
Sbjct: 900  EELKCQRDNKYSDLYEKYIKLIKSICMIINIECCDDIENEDIIRRIEEYINNNKGLKKEV 959

Query: 1417 YQKTHE--YTITLTQRNDEF--ENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANH 1472
             +K H+   +  + +  ++F   ++  +  E +K+ E     K+ E+     K+ E  N 
Sbjct: 960  EEKEHKRHSSFNILKSKEKFFKNSIEDKSHELKKKHEKDLLSKDKEIEEKNKKIKELNND 1019

Query: 1473 YETMQKESEI-ERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEI 1531
             + +Q E  + ++    ++++ K    + L  +  E  K  E ++      +  L+ ++ 
Sbjct: 1020 IKKLQDEILVYKKQSNAQQVDHKKKSWILLKDKSKEKIKDKENQINVEKNEEKDLKKKDD 1079

Query: 1532 EIVTLNDEITNLQNMV 1547
            EI  LN+E+   + ++
Sbjct: 1080 EIRILNEELVKYKTIL 1095



 Score =  119 bits (287), Expect = 6e-25
 Identities = 218/1189 (18%), Positives = 512/1189 (43%), Gaps = 129/1189 (10%)

Query: 475  VNEIAKVQEQLKQELNDEIKDVNV--KDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSN 532
            VN  +K++E L++EL  E+KD N+   D   KLK  E+ + Q  D ++   +N+++ K  
Sbjct: 149  VNYESKIEE-LEKELK-EVKDKNIDNNDYENKLKEKEDFVKQKIDMLNE-KENLLQEK-- 203

Query: 533  HKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSG- 591
             +L + + +K      K+++  K I++  E  H++ ++  E  +E+  + + ++D     
Sbjct: 204  -ELDINKREK------KINEKEKNIIKKEETFHNIEKEYLEKNKERETISIEIIDIKKHL 256

Query: 592  RMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQ 651
              ++ ++ +K  ++ENL +  L   ++L+  K  + ++   +    D + +K      L+
Sbjct: 257  EKLKIEIKEKKEDLENLNKKLLSKENVLKELKGCVKEKNETINSLNDNIIEKEKKYKLLE 316

Query: 652  SDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGT-IKDLENDKEDIMNKL 710
             + +  + K + L  + +     +KE     E  K +KE+ Y T IK+L+++K  I+ K+
Sbjct: 317  YE-LEEKNKQIDLLNKQEKEKEKEKEREKEKEREK-EKEKEYDTLIKELKDEKISILEKV 374

Query: 711  QNYIQENMDLTDKLEKM--SAEKISELLAK-INHEEQSKIQT----QFGIDAKIQERDLY 763
             +     MD+  +        +++ +L    + +  Q K+          + + +E++L 
Sbjct: 375  HSIKVREMDIEKREHNFLHMEDQLKDLKNSFVKNNNQLKVYKCEIKNLKTELEKKEKELK 434

Query: 764  -IENI-ESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQED 821
             IEN+ + E++K  +++   E+ I          + +   L   L+E  K     T +  
Sbjct: 435  DIENVSKEEINKLINQLNEKEKQILAFNKNH---KEEIHGLKEELKESVKITKIETQELQ 491

Query: 822  ELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVE 881
            E+V+      + D++ EK   +IE  + EL KK +   E NQ     + ++  + N  +E
Sbjct: 492  EMVD--IKQKELDQLQEKYNAQIESISIELSKKEK---EYNQYKNTYIEEIN-NLNEKLE 545

Query: 882  KANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIR 941
            + N+     +    Y  ++  L +++  +    +T+  Q      D+ +  N QI+    
Sbjct: 546  ETNKE--YTNLQNNYTNEINMLNNDIHMLNGNIKTMNTQISTLKNDVHL-LNEQIDKLNN 602

Query: 942  DKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSP 1001
            +K  LN K       +++L  Q+ + K   + LN  + +L+   ++L+ + +++++ +  
Sbjct: 603  EKGTLNSK-------ISELNVQIMDLKEEKDFLNNQIVDLSNQ-IDLLTRKMEEKENKML 654

Query: 1002 DYTEQYINEINKLNALLKQK------DEEIIALNQKINNAQVSYMSMVSDYESKLAQFTT 1055
            +   +Y  E+  L   +K        DEE+  L +K++  +     M  +++ KLA+   
Sbjct: 655  EQENKYKQEMELLRGNIKSSENILNNDEEVCDLKRKLSLKESEMKMMKEEHDKKLAELKD 714

Query: 1056 KL--------ENMEEEMQRVSKQLLDS----KQHNEE-LQILVREQDDQIKELKETKLTF 1102
                      E  E+++  + ++  D     K+ NE+ +  L  + +D+I  LKE +   
Sbjct: 715  DCDVRIREMNEKNEDKINMLKEEYEDKINTLKEQNEDKINTLKEQNEDKINTLKE-EYEH 773

Query: 1103 EMNIPKTEGMIISSTIEPMSDDANN---------VDXXXXXXXXXXXXLKVQEEEEFIQE 1153
            ++N  K E     +T+   ++   N         ++            L  Q E++    
Sbjct: 774  KINTMKEEYEHKINTLNEQNEHKINTLNEQNEHKINTMKEEYEDKMNTLNEQNEDKMNSL 833

Query: 1154 RSVLQEQSAKLNT----ELQECYTKIIQ-LETLNTELTGHDVVNQEQINQ---------- 1198
            +   + +  ++N+    ++++   + I+ ++ L   L        ++IN           
Sbjct: 834  KEEYENKINQINSNNEIKIKDVVNEYIEEVDKLKVTLDEKKKQFDKEINYAHIKAHEKEQ 893

Query: 1199 -LKSKLEQLNTENDNLLSTVAE-----LRS-----SISSAVDQRGFEIAELWKQHLAQRE 1247
             L +++E+L  + DN  S + E     ++S     +I    D    +I    ++++   +
Sbjct: 894  ILLTEMEELKCQRDNKYSDLYEKYIKLIKSICMIINIECCDDIENEDIIRRIEEYINNNK 953

Query: 1248 A---DFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEE 1304
                + ++ EH+     +  +SK +   +S++  + E   K    + + S   ++++K +
Sbjct: 954  GLKKEVEEKEHKRHSSFNILKSKEKFFKNSIEDKSHELKKK--HEKDLLSKDKEIEEKNK 1011

Query: 1305 HLRNLQEKYADVINQIEILRSE-----IEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSY 1359
             ++ L      + ++I + + +     ++ +K ++                 +  E    
Sbjct: 1012 KIKELNNDIKKLQDEILVYKKQSNAQQVDHKKKSWILLKDKSKEKIKDKENQINVEKNEE 1071

Query: 1360 KQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQK 1419
            K ++++    I   N +L K              +  D  +K+    + L + +     K
Sbjct: 1072 KDLKKKDD-EIRILNEELVKYKTILYNLKKDPLLQNQDLLSKID--INSLTINEGMCVDK 1128

Query: 1420 THEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYE------KESELAILRLKMHENANHY 1473
              E+ +     ++E    R  L + +  I  LT E      K++EL     K++      
Sbjct: 1129 IEEHILDY---DEEINKSRSNLFQLKNEICSLTTEVMELNNKKNELIEENNKLNLVDQGK 1185

Query: 1474 ETMQKESEIERVKLIEELNVKITESVS----LNKQVAELNKALEEEVAKTNEMQTALENQ 1529
            + ++K+ E ++ K IE+LN ++T+       LN++V +LN    E +  +N++    + +
Sbjct: 1186 KKLKKDVEKQK-KEIEKLNKQLTKCNKQIDELNEEVEKLNNENIELITYSNDLNNKFDMK 1244

Query: 1530 EIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNK 1578
            E  ++   DE  +    +++    ++K + +  D K+    +++N   K
Sbjct: 1245 ENNLMMKLDENEDNIKKMKSKIDDMEKEIKYREDEKKRNLNEINNLKKK 1293



 Score =  115 bits (277), Expect = 9e-24
 Identities = 260/1357 (19%), Positives = 562/1357 (41%), Gaps = 122/1357 (8%)

Query: 90   ISESLANTLKQKEILMEKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQ--LGDVTHL 147
            I+E   N +K++E      K+Y E +K   T  +                +    D+ +L
Sbjct: 214  INEKEKNIIKKEETFHNIEKEYLEKNKERETISIEIIDIKKHLEKLKIEIKEKKEDLENL 273

Query: 148  SNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXX 207
            +  +  K+N L  L+  +K    TI  L + I EK++      K                
Sbjct: 274  NKKLLSKENVLKELKGCVKEKNETINSLNDNIIEKEK------KYKLLEYELEEKNKQID 327

Query: 208  XXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEI 267
                ++ +++  K +E     E E + E   L+K++  KD +IS LE+ + +        
Sbjct: 328  LLNKQEKEKEKEKEREKEKEREKEKEKEYDTLIKEL--KDEKISILEKVHSIKVREMDIE 385

Query: 268  SLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIE--EKGSLEIANMT--E 323
              EH+ L  E +Q              L     E     KTE+E  EK   +I N++  E
Sbjct: 386  KREHNFLHME-DQLKDLKNSFVKNNNQLKVYKCEIK-NLKTELEKKEKELKDIENVSKEE 443

Query: 324  LTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMK 383
            + K I  L     QI   NK  + ++  +  E K     S K + + +++       K K
Sbjct: 444  INKLINQLNEKEKQILAFNKNHKEEIHGLKEELK----ESVKITKIETQELQEMVDIKQK 499

Query: 384  SPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXX 443
                QL  +   Q     I   E++K E          +++   ++EK            
Sbjct: 500  E-LDQLQEKYNAQIESISI---ELSKKEKEYNQYKNTYIEEINNLNEKLEETNKEYTNLQ 555

Query: 444  GKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDV-NEIAKVQEQLKQELNDEIKDVNVKDLI 502
               T    + L +  HM   ++  + T    + N++  + EQ+  +LN+E   +N     
Sbjct: 556  NNYTNEINM-LNNDIHMLNGNIKTMNTQISTLKNDVHLLNEQI-DKLNNEKGTLN----- 608

Query: 503  EKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTE 562
             K+     QI  L +E D  N  ++ + +   L  ++M++  +   +  +  K+ + L  
Sbjct: 609  SKISELNVQIMDLKEEKDFLNNQIVDLSNQIDLLTRKMEEKENKMLEQENKYKQEMELLR 668

Query: 563  ELHHLSQKVAELEEEKGNLQLHLVDYDSG-RMIESDVYKKMIEMENLAETRLKAISLLES 621
                 S+ +   +EE  +L+  L   +S  +M++ +  KK+ E+++  + R++ ++    
Sbjct: 669  GNIKSSENILNNDEEVCDLKRKLSLKESEMKMMKEEHDKKLAELKDDCDVRIREMNEKNE 728

Query: 622  QKFDLVQELH--ILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELA 679
             K ++++E +   +    ++ EDK+  + +   D++ + +K    EE    ++  K+E  
Sbjct: 729  DKINMLKEEYEDKINTLKEQNEDKINTLKEQNEDKI-NTLK----EEYEHKINTMKEEYE 783

Query: 680  LVIENLKLDKEQLYGTIKD-----LENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISE 734
              I  L    E    T+ +     +   KE+  +K+    ++N D  + L++    KI++
Sbjct: 784  HKINTLNEQNEHKINTLNEQNEHKINTMKEEYEDKMNTLNEQNEDKMNSLKEEYENKINQ 843

Query: 735  LLAK--------INH--EEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEES 784
            + +         +N   EE  K++       K  ++++   +I++   K +  +  +EE 
Sbjct: 844  INSNNEIKIKDVVNEYIEEVDKLKVTLDEKKKQFDKEINYAHIKAH-EKEQILLTEMEE- 901

Query: 785  IAVMEDRRYS-LERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLE 843
            +    D +YS L  K  +L   +           I+ ++++ R+   +++++ ++K++ E
Sbjct: 902  LKCQRDNKYSDLYEKYIKLIKSICMIINIECCDDIENEDIIRRIEEYINNNKGLKKEVEE 961

Query: 844  IEH---------ENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESEST 894
             EH         ++KE   KN I  + ++  +    D+      + EK  +     ++  
Sbjct: 962  KEHKRHSSFNILKSKEKFFKNSIEDKSHELKKKHEKDLLSKDKEIEEKNKKIKELNNDIK 1021

Query: 895  KYQTQL--RDLESNLKRITHEHQTLIVQK---KKEIEDLEIEFNTQ--IESAIRDK---- 943
            K Q ++     +SN +++ H+ ++ I+ K   K++I+D E + N +   E  ++ K    
Sbjct: 1022 KLQDEILVYKKQSNAQQVDHKKKSWILLKDKSKEKIKDKENQINVEKNEEKDLKKKDDEI 1081

Query: 944  KVLNE---KYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNK-MNLELIDKHV---QKQ 996
            ++LNE   KY K I Y  + +  LQ  ++ +  +++N   +N+ M ++ I++H+    ++
Sbjct: 1082 RILNEELVKY-KTILYNLKKDPLLQN-QDLLSKIDINSLTINEGMCVDKIEEHILDYDEE 1139

Query: 997  QTQSPDYTEQYINEINKLNA---LLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQF 1053
              +S     Q  NEI  L      L  K  E+I  N K+N        +  D E +    
Sbjct: 1140 INKSRSNLFQLKNEICSLTTEVMELNNKKNELIEENNKLNLVDQGKKKLKKDVEKQ---- 1195

Query: 1054 TTKLENMEEEMQRVSKQLLD-----SKQHNEELQILVREQDDQIK-ELKETKLTFEMNIP 1107
              ++E + +++ + +KQ+ +      K +NE ++++    D   K ++KE  L  +++  
Sbjct: 1196 KKEIEKLNKQLTKCNKQIDELNEEVEKLNNENIELITYSNDLNNKFDMKENNLMMKLDEN 1255

Query: 1108 KTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSV------LQEQS 1161
            +     + S I+ M  +    +            LK + E+  I+   +      +  + 
Sbjct: 1256 EDNIKKMKSKIDDMEKEIKYREDEKKRNLNEINNLKKKNEDMCIKYNEMNIKYGDICVKY 1315

Query: 1162 AKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELR 1221
             +++   +E   K  Q++    E        + Q ++   + +++N +   LL+ +    
Sbjct: 1316 EEMSLTYKETSLKYEQIKVKYDEKCSQYDEIRFQYDEKCFQYDEINKKYGALLN-INITN 1374

Query: 1222 SSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQE 1281
              + S VD+   EI  +   +  +  A++ K   EL  ++   + +  ++     +   E
Sbjct: 1375 KMVDSKVDRNNNEIISV--DNKVEGIANYLKQIFELNEEIIRLKGEINKISLLYSNELNE 1432

Query: 1282 ETNKIVTM----EQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXX 1337
            + +  + M    EQ+  L+   ++ EE + NL  +Y+D        + + ++ K+     
Sbjct: 1433 KNSYDINMKHIQEQLLFLEKTNKENEEKIINLTSQYSDA------YKKKSDESKLCGAQF 1486

Query: 1338 XXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEEN 1374
                         ++RT    Y++M +    NI E+N
Sbjct: 1487 VDDVNIYGNISNNNIRTNEYKYEEMFD---TNIEEKN 1520



 Score =  109 bits (262), Expect = 6e-22
 Identities = 256/1250 (20%), Positives = 552/1250 (44%), Gaps = 99/1250 (7%)

Query: 143  DVTHLSNTIKEKDN----ALSVLQVKMKIMETTILDL---QEKINEKDQ-IIEAKNKATT 194
            D     N +KEK++     + +L  K  +++   LD+   ++KINEK++ II+ +     
Sbjct: 171  DNNDYENKLKEKEDFVKQKIDMLNEKENLLQEKELDINKREKKINEKEKNIIKKEETFHN 230

Query: 195  XXXXXXXXXXXXXXXXXE--DTKQQMTKMQENFIAMEAEWKDEKQRLL-KDIESKDVRIS 251
                             E  D K+ + K++      + + ++  ++LL K+   K+++  
Sbjct: 231  IEKEYLEKNKERETISIEIIDIKKHLEKLKIEIKEKKEDLENLNKKLLSKENVLKELK-G 289

Query: 252  SLEEANKLLEAARFEISLEHSK---LAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKT 308
             ++E N+ + +    I  +  K   L  ELE+                K+  E   E++ 
Sbjct: 290  CVKEKNETINSLNDNIIEKEKKYKLLEYELEEKNKQIDLLNKQEKEKEKEK-EREKEKER 348

Query: 309  EIEEKGSLEIANMTELTKKIELLEHL-NCQIRQTN-KELENKLATMGTESKAV-SSPSKK 365
            E E++   +        +KI +LE + + ++R+ + ++ E+    M  + K + +S  K 
Sbjct: 349  EKEKEKEYDTLIKELKDEKISILEKVHSIKVREMDIEKREHNFLHMEDQLKDLKNSFVKN 408

Query: 366  GSPL-ISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINK--NEIAKLEMVIQSLNKDLV 422
             + L + +   +N  ++++    +L  + +   + ++INK  N++ + E  I + NK+  
Sbjct: 409  NNQLKVYKCEIKNLKTELEKKEKEL--KDIENVSKEEINKLINQLNEKEKQILAFNKNHK 466

Query: 423  DKEYVISE--KDTXXXXXXXXXXGKDTL------IAQLQLEHQQHMEGPSLIHVGTNTED 474
            ++ + + E  K++           ++ +      + QLQ ++   +E  S I +    ++
Sbjct: 467  EEIHGLKEELKESVKITKIETQELQEMVDIKQKELDQLQEKYNAQIESIS-IELSKKEKE 525

Query: 475  VNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHK 534
             N+      +    LN+++++ N K+      +   +I  LN++I   N N IK  +   
Sbjct: 526  YNQYKNTYIEEINNLNEKLEETN-KEYTNLQNNYTNEINMLNNDIHMLNGN-IKTMNTQI 583

Query: 535  LKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMI 594
              LK     ++   ++   N E   L  ++  L+ ++ +L+EEK  L   +VD  +   I
Sbjct: 584  STLKNDVHLLN--EQIDKLNNEKGTLNSKISELNVQIMDLKEEKDFLNNQIVDLSN--QI 639

Query: 595  ESDVYKKMIEMEN-LAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSD 653
            +  + +KM E EN + E   K    +E  + ++    +IL    +EV D    +S  +S+
Sbjct: 640  DL-LTRKMEEKENKMLEQENKYKQEMELLRGNIKSSENILNND-EEVCDLKRKLSLKESE 697

Query: 654  -QVCSEIKSVHLEEQIDALSASKKELALVIEN-LKLDKEQLYGTIKDLENDKEDIMNKLQ 711
             ++  E     L E  D      +E+    E+ + + KE+    I  L+   ED +N L+
Sbjct: 698  MKMMKEEHDKKLAELKDDCDVRIREMNEKNEDKINMLKEEYEDKINTLKEQNEDKINTLK 757

Query: 712  NYIQENMDLTDKLEKMSAEKISELLAKINHEEQS-KIQTQFGIDAKIQERDLYIENIESE 770
               ++N D  + L++    KI+ +  +  H+  +   Q +  I+   ++ +  I  ++ E
Sbjct: 758  ---EQNEDKINTLKEEYEHKINTMKEEYEHKINTLNEQNEHKINTLNEQNEHKINTMKEE 814

Query: 771  LSKYKSRICRL-EESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAV 829
               Y+ ++  L E++   M   +   E K +Q+ S  + K K      I+E   V++L V
Sbjct: 815  ---YEDKMNTLNEQNEDKMNSLKEEYENKINQINSNNEIKIKDVVNEYIEE---VDKLKV 868

Query: 830  LMDHDRVVEKQL-LEIEHENKELQKKNQILLEENQNLQI----SLSDMQQHYNALVEK-- 882
             +D  +   KQ   EI + + +  +K QILL E + L+       SD+ + Y  L++   
Sbjct: 869  TLDEKK---KQFDKEINYAHIKAHEKEQILLTEMEELKCQRDNKYSDLYEKYIKLIKSIC 925

Query: 883  --ANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAI 940
               N     + E+     ++ +  +N K +  E +    ++      L+ +     +++I
Sbjct: 926  MIINIECCDDIENEDIIRRIEEYINNNKGLKKEVEEKEHKRHSSFNILKSK-EKFFKNSI 984

Query: 941  RDKK-VLNEKYEKNI----EYVTQLEAQLQEYKNNIENLNMNVEELNKM-NLELIDKHVQ 994
             DK   L +K+EK++    + + +   +++E  N+I+ L   +    K  N + +D H +
Sbjct: 985  EDKSHELKKKHEKDLLSKDKEIEEKNKKIKELNNDIKKLQDEILVYKKQSNAQQVD-HKK 1043

Query: 995  KQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFT 1054
            K      D +++ I +  K N +  +K+EE   L +K +  ++    +V  Y++ L  + 
Sbjct: 1044 KSWILLKDKSKEKIKD--KENQINVEKNEE-KDLKKKDDEIRILNEELVK-YKTIL--YN 1097

Query: 1055 TKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMII 1114
             K + + +    +SK  ++S   NE +   V + ++ I +  E       N+ + +  I 
Sbjct: 1098 LKKDPLLQNQDLLSKIDINSLTINEGM--CVDKIEEHILDYDEEINKSRSNLFQLKNEIC 1155

Query: 1115 SSTIEPMS-DDANN--VDXXXXXXXXXXXXLKVQEE-EEFIQERSVLQEQSAKLNTELQE 1170
            S T E M  ++  N  ++             K++++ E+  +E   L +Q  K N ++ E
Sbjct: 1156 SLTTEVMELNNKKNELIEENNKLNLVDQGKKKLKKDVEKQKKEIEKLNKQLTKCNKQIDE 1215

Query: 1171 CYTKIIQLETLNTELT--GHDVVNQEQI--NQLKSKLEQLNTENDNLLSTVAELRSSISS 1226
               ++ +L   N EL    +D+ N+  +  N L  KL++       + S + ++   I  
Sbjct: 1216 LNEEVEKLNNENIELITYSNDLNNKFDMKENNLMMKLDENEDNIKKMKSKIDDMEKEIKY 1275

Query: 1227 AVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQL-LDSVQSSTQEETNK 1285
              D++   + E+   +L ++  D     +E+ ++      KYE++ L   ++S + E  K
Sbjct: 1276 REDEKKRNLNEI--NNLKKKNEDMCIKYNEMNIKYGDICVKYEEMSLTYKETSLKYEQIK 1333

Query: 1286 IVTME---QVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKV 1332
            +   E   Q   ++ +  +K      + +KY  ++N I I  +++ D KV
Sbjct: 1334 VKYDEKCSQYDEIRFQYDEKCFQYDEINKKYGALLN-INI-TNKMVDSKV 1381



 Score = 38.7 bits (86), Expect = 1.3
 Identities = 45/226 (19%), Positives = 97/226 (42%), Gaps = 25/226 (11%)

Query: 1355 ENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQL-ELKD 1413
            +N ++    ++   NI  ++ +L+               ++ + E+K+ EL  +L E+KD
Sbjct: 108  DNNNFNNYSDEISKNIIHKDNELENQLKDTLKSISSLSNKIVNYESKIEELEKELKEVKD 167

Query: 1414 SEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHY 1473
              I              N+++EN  ++  ++ K+  D+  EKE+ L    L +  N    
Sbjct: 168  KNI-------------DNNDYENKLKEKEDFVKQKIDMLNEKENLLQEKELDI--NKREK 212

Query: 1474 ETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEI 1533
            +  +KE  I  +K  E  +       ++ K+  E NK  E    +  +++  LE  +IEI
Sbjct: 213  KINEKEKNI--IKKEETFH-------NIEKEYLEKNKERETISIEIIDIKKHLEKLKIEI 263

Query: 1534 VTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKE 1579
                +++ NL   + +  + +++      +  +  +   DN + KE
Sbjct: 264  KEKKEDLENLNKKLLSKENVLKELKGCVKEKNETINSLNDNIIEKE 309


>UniRef50_Q15075 Cluster: Early endosome antigen 1; n=30;
            Euteleostomi|Rep: Early endosome antigen 1 - Homo sapiens
            (Human)
          Length = 1411

 Score =  131 bits (317), Expect = 1e-28
 Identities = 244/1161 (21%), Positives = 496/1161 (42%), Gaps = 126/1161 (10%)

Query: 477  EIAKVQEQLKQELNDEIK-DVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKL 535
            E+ K  E+ +     E K D  V D   +L+S E+Q+    +E    N N+ ++K   + 
Sbjct: 108  ELKKELEKYQGLQQQEAKPDGLVTDSSAELQSLEQQL----EEAQTENFNIKQMKDLFEQ 163

Query: 536  KLKQMQKTIDNFSKVSDSNK--------EIVRLTEELHHLSQKVAELEEEKGNLQLHLVD 587
            K  Q+   I +     D  +        ++ RLTEEL+  +  + +L+ E     L    
Sbjct: 164  KAAQLATEIADIKSKYDEERSLREAAEQKVTRLTEELNKEATVIQDLKTEL----LQRPG 219

Query: 588  YDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADI 647
             +   +++ ++ +    M+N+   R +     ES+K  L  E   LQ +Y   E   A I
Sbjct: 220  IEDVAVLKKELVQVQTLMDNMTLERER-----ESEK--LKDECKKLQSQYASSE---ATI 269

Query: 648  SQLQSDQVCSEIKSVHLEEQIDALSASKKELA----LVIENLKLDKEQLYGTIKDLENDK 703
            SQL+S+      +     +++  L +S  EL      + ENL L KEQ Y  +++  N++
Sbjct: 270  SQLRSELAKGPQEVAVYVQELQKLKSSVNELTQKNQTLTENL-LKKEQDYTKLEEKHNEE 328

Query: 704  EDIMNKLQNYI-QENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDL 762
                  +Q  + Q+++D      ++SA + S  L +I+ E   K +       K++E   
Sbjct: 329  SVSKKNIQATLHQKDLDCQQLQSRLSASETS--LHRIHVELSEKGEAT----QKLKEE-- 380

Query: 763  YIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEY--TIQE 820
             +  +E++    K+   +L++     E     L+ + +QL S L E ++   E    ++E
Sbjct: 381  -LSEVETKYQHLKAEFKQLQQQREEKEQHGLQLQSEINQLHSKLLETERQLGEAHGRLKE 439

Query: 821  DELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALV 880
               ++    LMD ++ V    L++    ++L++K    +  +  LQ  L   +Q +    
Sbjct: 440  QRQLSS-EKLMDKEQQVADLQLKLSRLEEQLKEK----VTNSTELQHQLDKTKQQHQ--- 491

Query: 881  EKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTL-----IVQKKKE----IEDLEIE 931
                +  L +S + K +    DLE  L++I  + Q +     ++QK KE    +E    +
Sbjct: 492  ---EQQALQQSTTAKLREAQNDLEQVLRQIGDKDQKIQNLEALLQKSKENISLLEKERED 548

Query: 932  FNTQIESAIRDKKVLNEKYEKNI---EYVTQLEAQL----QEYKNNIENLNMNVEELNKM 984
               +I++   +  VLN+  EKN    E VTQL  +L    + +K   ENL+  V+E  K 
Sbjct: 549  LYAKIQAGEGETAVLNQLQEKNHTLQEQVTQLTEKLKNQSESHKQAQENLHDQVQE-QKA 607

Query: 985  NLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVS 1044
            +L      V   +T   +   Q    +N+    + Q D +I A  + + +A+ +  +  +
Sbjct: 608  HLRAAQDRVLSLETSVNELNSQ----LNESKEKVSQLDIQIKAKTELLLSAEAAKTAQRA 663

Query: 1045 DYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEM 1104
            D ++ L      L++ ++E+ +++ QL       ++ Q    + +  +KE KE  L+ E 
Sbjct: 664  DLQNHLDTAQNALQDKQQELNKITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQ 723

Query: 1105 NIPKTEGMI---------ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQ---EEEEFIQ 1152
               + EG I         + ++ E    D                 L  Q   E+E    
Sbjct: 724  KTEELEGQIKKLEADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEIVSS 783

Query: 1153 ERSVLQEQSAKLNT-----ELQECYTKIIQ--LETLNTEL-TGHDVVNQEQINQLKSKLE 1204
             R  LQ++S  L +       QE   +I++   ETL+ E    H+ +N  +I    ++L+
Sbjct: 784  TRLDLQKKSEALESIKQKLTKQEEEKQILKQDFETLSQETKIQHEELN-NRIQTTVTELQ 842

Query: 1205 QLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREA--DFQKT----EHELR 1258
            ++  E + L++ ++ ++  +S   D      +E  K++   + A  D +KT    +H+L+
Sbjct: 843  KVKMEKEALMTELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKELKHQLQ 902

Query: 1259 VQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVIN 1318
            VQ+     + ++L  S++   ++E +  + +E + S+Q +L   +  L+  +++   +  
Sbjct: 903  VQMENTLKEQKELKKSLEK--EKEASHQLKLE-LNSMQEQLIQAQNTLKQNEKEEQQLQG 959

Query: 1319 QIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLK 1378
             I  L+   E +K                   +L  + Q       Q +    E+ + L+
Sbjct: 960  NINELKQSSEQKKKQI-EALQGELKIAVLQKTELENKLQQQLTQAAQELAAEKEKISVLQ 1018

Query: 1379 KSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVR 1438
             +                  E+++L     L         K+ E  ++L Q  D   N R
Sbjct: 1019 NNYEKSQETFKQLQSDFYGRESELLATRQDL---------KSVEEKLSLAQ-EDLISN-R 1067

Query: 1439 QQLVEYEKRIEDLTYEK---ESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKI 1495
             Q+    K I++L   K   E + A    ++ E     + +QKE  ++  +L+ E + K+
Sbjct: 1068 NQIGNQNKLIQELKTAKATLEQDSAKKEQQLQERCKALQDIQKEKSLKEKELVNEKS-KL 1126

Query: 1496 TESVSL----NKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASS 1551
             E   +     K++ +LN+ L+    ++ +  T L++ +  ++    E+    + ++A+ 
Sbjct: 1127 AEIEEIKCRQEKEITKLNEELKSHKLESIKEITNLKDAKQLLIQQKLELQGKADSLKAAV 1186

Query: 1552 SKIQKHVSFASDTKQGRDEQL 1572
             + +++     D  +  +E+L
Sbjct: 1187 EQEKRNQQILKDQVKKEEEEL 1207



 Score =  131 bits (317), Expect = 1e-28
 Identities = 235/1203 (19%), Positives = 501/1203 (41%), Gaps = 95/1203 (7%)

Query: 388  QLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKD- 446
            +  +E  N    K + + + A+L   I  + K   D+E  + E              K+ 
Sbjct: 146  EAQTENFNIKQMKDLFEQKAAQLATEIADI-KSKYDEERSLREAAEQKVTRLTEELNKEA 204

Query: 447  TLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQL---KQELNDEIKDVNVKDLIE 503
            T+I  L+ E  Q    P +  V    +++ ++  + + +   ++  ++++KD   K L  
Sbjct: 205  TVIQDLKTELLQR---PGIEDVAVLKKELVQVQTLMDNMTLERERESEKLKD-ECKKLQS 260

Query: 504  KLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEE 563
            +  S+E  I+QL  E+ A     + V      KLK     +   ++    N  +++  ++
Sbjct: 261  QYASSEATISQLRSEL-AKGPQEVAVYVQELQKLKSSVNELTQKNQTLTEN--LLKKEQD 317

Query: 564  LHHLSQKVAELEEEKGNLQ--LHLVDYDSGRM------IESDVYKKMIEMENLAETRLKA 615
               L +K  E    K N+Q  LH  D D  ++       E+ +++  +E+    E   K 
Sbjct: 318  YTKLEEKHNEESVSKKNIQATLHQKDLDCQQLQSRLSASETSLHRIHVELSEKGEATQKL 377

Query: 616  ---ISLLESQKFDLVQELHILQQKYDEVEDK----LADISQLQSDQVCSE--IKSVH--L 664
               +S +E++   L  E   LQQ+ +E E       ++I+QL S  + +E  +   H  L
Sbjct: 378  KEELSEVETKYQHLKAEFKQLQQQREEKEQHGLQLQSEINQLHSKLLETERQLGEAHGRL 437

Query: 665  EEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKL 724
            +EQ    S    +    + +L+L   +L   +K+   +  ++ ++L    Q++ +    L
Sbjct: 438  KEQRQLSSEKLMDKEQQVADLQLKLSRLEEQLKEKVTNSTELQHQLDKTKQQHQE-QQAL 496

Query: 725  EKMSAEKISEL---LAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRL 781
            ++ +  K+ E    L ++  +   K Q    ++A +Q+    I  +E E     ++I   
Sbjct: 497  QQSTTAKLREAQNDLEQVLRQIGDKDQKIQNLEALLQKSKENISLLEKEREDLYAKIQAG 556

Query: 782  EESIAVM---EDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVE 838
            E   AV+   +++ ++L+ +  QL   L+ + +++ +    ++ L +++     H R  +
Sbjct: 557  EGETAVLNQLQEKNHTLQEQVTQLTEKLKNQSESHKQ---AQENLHDQVQEQKAHLRAAQ 613

Query: 839  KQLLEIEHENKELQKKNQILLEENQNLQISL-SDMQQHYNALVEK-ANRTDLAESESTKY 896
             ++L +E    EL  +     E+   L I + +  +   +A   K A R DL     T  
Sbjct: 614  DRVLSLETSVNELNSQLNESKEKVSQLDIQIKAKTELLLSAEAAKTAQRADLQNHLDTA- 672

Query: 897  QTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKV----LNEKYEK 952
            Q  L+D +  L +IT    T + Q   +++D + E  +Q+ES +++ K     L +K E+
Sbjct: 673  QNALQDKQQELNKIT----TQLDQVTAKLQDKQ-EHCSQLESHLKEYKEKYLSLEQKTEE 727

Query: 953  NIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEIN 1012
                + +LEA   E K + E    ++++  ++N +L     + + T+     E     ++
Sbjct: 728  LEGQIKKLEADSLEVKASKEQALQDLQQQRQLNTDL-----ELRATELSKQLEMEKEIVS 782

Query: 1013 KLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLL 1072
                 L++K E + ++ QK+   +     +  D+E+   +   + E +   +Q    +L 
Sbjct: 783  STRLDLQKKSEALESIKQKLTKQEEEKQILKQDFETLSQETKIQHEELNNRIQTTVTELQ 842

Query: 1073 DSKQHNEELQILVREQDDQIKE----LKETKLTFEMNIPKTEGMIISSTIEPMSDDANNV 1128
              K   E L   +    D++ +    LK +K  FE    K +  I+   +E    +  + 
Sbjct: 843  KVKMEKEALMTELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAILD--LEKTCKELKH- 899

Query: 1129 DXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGH 1188
                         LK Q+E +   E+   +E S +L  EL     ++IQ +    +    
Sbjct: 900  ----QLQVQMENTLKEQKELKKSLEKE--KEASHQLKLELNSMQEQLIQAQNTLKQ---- 949

Query: 1189 DVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREA 1248
               N+++  QL+  + +L   ++     +  L+  +  AV Q+  E+    +Q L Q   
Sbjct: 950  ---NEKEEQQLQGNINELKQSSEQKKKQIEALQGELKIAVLQKT-ELENKLQQQLTQAAQ 1005

Query: 1249 DFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRN 1308
            +    + ++ V  + +E   E            E+  + T + + S++ KL   +E L +
Sbjct: 1006 ELAAEKEKISVLQNNYEKSQETFKQLQSDFYGRESELLATRQDLKSVEEKLSLAQEDLIS 1065

Query: 1309 LQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSIL 1368
             + +     NQ ++++ E++  K                    L+ + Q  K ++E+ ++
Sbjct: 1066 NRNQIG---NQNKLIQ-ELKTAKATLEQDSAKKEQQLQERCKALQ-DIQKEKSLKEKELV 1120

Query: 1369 NINEENAQLKKSSXXXXXXXXXXXXRVNDAEAK-VLELTHQLELKDSEIYQKTH-EYTIT 1426
            N   + A++++               +   + + + E+T+  + K   I QK   +    
Sbjct: 1121 NEKSKLAEIEEIKCRQEKEITKLNEELKSHKLESIKEITNLKDAKQLLIQQKLELQGKAD 1180

Query: 1427 LTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVK 1486
              +   E E   QQ+++ + + E+   E + E      K+H      E   K+ E    K
Sbjct: 1181 SLKAAVEQEKRNQQILKDQVKKEE--EELKKEFIEKEAKLHSEIKEKEVGMKKHEENEAK 1238

Query: 1487 LIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNM 1546
                L ++IT   +LN+ +  + K  +    + +E++   ++   EI  L   + N Q+ 
Sbjct: 1239 ----LTMQIT---ALNENLGTVKKEWQSSQRRVSELEKQTDDLRGEIAVLEATVQNNQDE 1291

Query: 1547 VRA 1549
             RA
Sbjct: 1292 RRA 1294



 Score =  120 bits (290), Expect = 3e-25
 Identities = 222/1145 (19%), Positives = 477/1145 (41%), Gaps = 110/1145 (9%)

Query: 212  EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRI--SSLEEANKLLEAARFEISL 269
            E  +Q++T++ E         +D K  LL+    +DV +    L +   L++    E   
Sbjct: 187  EAAEQKVTRLTEELNKEATVIQDLKTELLQRPGIEDVAVLKKELVQVQTLMDNMTLERER 246

Query: 270  EHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIE 329
            E  KL  E ++              L  +  +   E    ++E   L+ +++ ELT+K +
Sbjct: 247  ESEKLKDECKKLQSQYASSEATISQLRSELAKGPQEVAVYVQELQKLK-SSVNELTQKNQ 305

Query: 330  LLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQL 389
             L     +  Q   +LE K        K + +   +      +   R +AS+       +
Sbjct: 306  TLTENLLKKEQDYTKLEEKHNEESVSKKNIQATLHQKDLDCQQLQSRLSASETSLHRIHV 365

Query: 390  SSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLI 449
                  + T K   K E++++E   Q L  +    +    EK+                 
Sbjct: 366  ELSEKGEATQKL--KEELSEVETKYQHLKAEFKQLQQQREEKEQHG-------------- 409

Query: 450  AQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQE-LNDEIKDVNVKDLIEKLKSA 508
              LQL+ + +     L+       + +   K Q QL  E L D  K+  V DL  KL   
Sbjct: 410  --LQLQSEINQLHSKLLETERQLGEAHGRLKEQRQLSSEKLMD--KEQQVADLQLKLSRL 465

Query: 509  EEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLS 568
            EEQ+ +           + K K  H+ +    Q T    +K+ ++  ++ ++  ++    
Sbjct: 466  EEQLKEKVTNSTELQHQLDKTKQQHQEQQALQQSTT---AKLREAQNDLEQVLRQIGDKD 522

Query: 569  QKVAELEE--EKGNLQLHLVDYDSGRMIESDVYKKMI--EMENLAETRLKAIS-LLESQK 623
            QK+  LE   +K    + L++ +       D+Y K+   E E     +L+  +  L+ Q 
Sbjct: 523  QKIQNLEALLQKSKENISLLEKE-----REDLYAKIQAGEGETAVLNQLQEKNHTLQEQV 577

Query: 624  FDLVQELHILQQKYDEVEDKLADISQLQSDQV-CSEIKSVHLEEQIDALSA----SKKEL 678
              L ++L    + + + ++ L D  Q Q   +  ++ + + LE  ++ L++    SK+++
Sbjct: 578  TQLTEKLKNQSESHKQAQENLHDQVQEQKAHLRAAQDRVLSLETSVNELNSQLNESKEKV 637

Query: 679  ALVIENLKLDKEQLYGTIK-------DLENDKEDIMNKLQNYIQENMDLTDKLEKMSA-- 729
            + +   +K   E L            DL+N  +   N LQ+  QE   +T +L++++A  
Sbjct: 638  SQLDIQIKAKTELLLSAEAAKTAQRADLQNHLDTAQNALQDKQQELNKITTQLDQVTAKL 697

Query: 730  EKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVME 789
            +   E  +++    +   +    ++ K +E +  I+ +E++  + K+   +  + +    
Sbjct: 698  QDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQIKKLEADSLEVKASKEQALQDLQQQR 757

Query: 790  DRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDH--DRVVEKQLLEIEHE 847
                 LE +A +L   L+ +++  S   +   +    L  +      +  EKQ+L+ + E
Sbjct: 758  QLNTDLELRATELSKQLEMEKEIVSSTRLDLQKKSEALESIKQKLTKQEEEKQILKQDFE 817

Query: 848  NKELQKKNQILLEE-NQNLQISLSDMQQHYNALVEKANRTDLA--ESESTKYQTQLRDLE 904
               L ++ +I  EE N  +Q +++++Q+    + ++A  T+L+  + + +K    L++ +
Sbjct: 818  T--LSQETKIQHEELNNRIQTTVTELQKV--KMEKEALMTELSTVKDKLSKVSDSLKNSK 873

Query: 905  SNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQL 964
            S  ++   + +  I+  +K  ++L+ +   Q+E+ ++++K L +  EK  E   QL+   
Sbjct: 874  SEFEKENQKGKAAILDLEKTCKELKHQLQVQMENTLKEQKELKKSLEKEKEASHQLKL-- 931

Query: 965  QEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEE 1024
                           ELN M  +LI      +Q +  +  +Q    IN+L    +QK ++
Sbjct: 932  ---------------ELNSMQEQLIQAQNTLKQNEKEE--QQLQGNINELKQSSEQKKKQ 974

Query: 1025 IIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQIL 1084
            I AL  ++  A +    + +  + +L Q   +L   +E++  +      S++  ++LQ  
Sbjct: 975  IEALQGELKIAVLQKTELENKLQQQLTQAAQELAAEKEKISVLQNNYEKSQETFKQLQSD 1034

Query: 1085 VREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKV 1144
               ++ ++   ++   + E  +   +  +IS+         N +                
Sbjct: 1035 FYGRESELLATRQDLKSVEEKLSLAQEDLISNR--------NQIGNQNKLI--------- 1077

Query: 1145 QEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLE 1204
               +E    ++ L++ SAK   +LQE   +   L+ +  E +   +  +E +N+ KSKL 
Sbjct: 1078 ---QELKTAKATLEQDSAKKEQQLQE---RCKALQDIQKEKS---LKEKELVNE-KSKLA 1127

Query: 1205 QLNTENDNLLSTVAELRSSISSAVDQRGFEIAELW--KQHLAQREADFQKTEHELRVQLS 1262
            ++          + +L   + S   +   EI  L   KQ L Q++ + Q     L+  + 
Sbjct: 1128 EIEEIKCRQEKEITKLNEELKSHKLESIKEITNLKDAKQLLIQQKLELQGKADSLKAAVE 1187

Query: 1263 AFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEI 1322
              E + +Q+L   Q   +EE  K   +E+   L +++++KE  ++  +E  A +  QI  
Sbjct: 1188 Q-EKRNQQILKD-QVKKEEEELKKEFIEKEAKLHSEIKEKEVGMKKHEENEAKLTMQITA 1245

Query: 1323 LRSEI 1327
            L   +
Sbjct: 1246 LNENL 1250



 Score =  110 bits (265), Expect = 3e-22
 Identities = 205/933 (21%), Positives = 384/933 (41%), Gaps = 72/933 (7%)

Query: 162  QVKMKIMETTILDLQ-EKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQ--- 217
            Q+K K+  +T L  Q +K  ++ Q  +A  ++TT                  D  Q+   
Sbjct: 468  QLKEKVTNSTELQHQLDKTKQQHQEQQALQQSTTAKLREAQNDLEQVLRQIGDKDQKIQN 527

Query: 218  ----MTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLE------AARFEI 267
                + K +EN   +E E +D   ++    E +   ++ L+E N  L+        + + 
Sbjct: 528  LEALLQKSKENISLLEKEREDLYAKIQAG-EGETAVLNQLQEKNHTLQEQVTQLTEKLKN 586

Query: 268  SLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMT-ELTK 326
              E  K AQE                     S+E S  E      +   +++ +  ++  
Sbjct: 587  QSESHKQAQENLHDQVQEQKAHLRAAQDRVLSLETSVNELNSQLNESKEKVSQLDIQIKA 646

Query: 327  KIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPW 386
            K ELL            +L+N L T     +       K +  + + + +      +   
Sbjct: 647  KTELLLSAEAAKTAQRADLQNHLDTAQNALQDKQQELNKITTQLDQVTAK--LQDKQEHC 704

Query: 387  SQLSSETLNQDTDKKIN-KNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGK 445
            SQL S  L +  +K ++ + +  +LE  I+ L  D +  E   S++              
Sbjct: 705  SQLESH-LKEYKEKYLSLEQKTEELEGQIKKLEADSL--EVKASKEQALQDLQQQRQLNT 761

Query: 446  DTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELN--DEIKDVNVKDLIE 503
            D  +   +L  Q  ME      V +   D+ + ++  E +KQ+L   +E K +  +D   
Sbjct: 762  DLELRATELSKQLEMEKEI---VSSTRLDLQKKSEALESIKQKLTKQEEEKQILKQDFET 818

Query: 504  KLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEE 563
              +  + Q  +LN+ I      + KVK   +  + ++    D  SKVSDS K      E+
Sbjct: 819  LSQETKIQHEELNNRIQTTVTELQKVKMEKEALMTELSTVKDKLSKVSDSLKNSKSEFEK 878

Query: 564  LHHLSQK-VAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQ 622
             +   +  + +LE+    L+  L       + E    KK +E E  A  +LK    L S 
Sbjct: 879  ENQKGKAAILDLEKTCKELKHQLQVQMENTLKEQKELKKSLEKEKEASHQLKLE--LNSM 936

Query: 623  KFDLVQELHILQQKYDEVEDKLADISQLQ--SDQVCSEIKSVHLEEQIDALSASKKELAL 680
            +  L+Q  + L+Q   E +    +I++L+  S+Q   +I+++  E +I  L   K EL  
Sbjct: 937  QEQLIQAQNTLKQNEKEEQQLQGNINELKQSSEQKKKQIEALQGELKIAVLQ--KTEL-- 992

Query: 681  VIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKIN 740
              EN KL ++QL    ++L  +KE I + LQN  +++ +   +L+     + SELLA   
Sbjct: 993  --EN-KL-QQQLTQAAQELAAEKEKI-SVLQNNYEKSQETFKQLQSDFYGRESELLA--T 1045

Query: 741  HEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKAD 800
             ++   ++ +  +     + DL I N  +++      I  L+ + A +E      E++  
Sbjct: 1046 RQDLKSVEEKLSL----AQEDL-ISN-RNQIGNQNKLIQELKTAKATLEQDSAKKEQQLQ 1099

Query: 801  QLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLE 860
            +    LQ+ QK   E +++E ELVN  + L + + +  +Q  EI   N+EL+      ++
Sbjct: 1100 ERCKALQDIQK---EKSLKEKELVNEKSKLAEIEEIKCRQEKEITKLNEELKSHKLESIK 1156

Query: 861  ENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQ 920
            E  NL+ +   + Q    L  KA+    A  +  + Q  L+D      ++  E + L   
Sbjct: 1157 EITNLKDAKQLLIQQKLELQGKADSLKAAVEQEKRNQQILKD------QVKKEEEEL--- 1207

Query: 921  KKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKN----IEYVTQLEAQLQEYKNNIENLNM 976
             KKE     IE   ++ S I++K+V  +K+E+N       +T L   L   K   ++   
Sbjct: 1208 -KKEF----IEKEAKLHSEIKEKEVGMKKHEENEAKLTMQITALNENLGTVKKEWQSSQR 1262

Query: 977  NVEELNKMNLELIDKHVQKQQT--QSPDYTEQYINEINKLNALLKQKDEEIIALNQKINN 1034
             V EL K   +L  +    + T   + D     +    K    +++   +++ L +K++N
Sbjct: 1263 RVSELEKQTDDLRGEIAVLEATVQNNQDERRALLERCLKGEGEIEKLQTKVLELQRKLDN 1322

Query: 1035 AQVSYMSMVSDYESKLAQFTTKLENMEEEMQRV 1067
               +   +  + +S   + T  L     E   V
Sbjct: 1323 TTAAVQELGRENQSLQIKHTQALNRKWAEDNEV 1355



 Score =  104 bits (249), Expect = 2e-20
 Identities = 201/1026 (19%), Positives = 439/1026 (42%), Gaps = 102/1026 (9%)

Query: 146  HLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXX 205
            ++  T+ +KD     LQ ++   ET++  +  +++EK    EA  K              
Sbjct: 334  NIQATLHQKDLDCQQLQSRLSASETSLHRIHVELSEKG---EATQK-LKEELSEVETKYQ 389

Query: 206  XXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEE-----ANKLL 260
                  +  +QQ  + +++ + +++E      +LL+           L+E     + KL+
Sbjct: 390  HLKAEFKQLQQQREEKEQHGLQLQSEINQLHSKLLETERQLGEAHGRLKEQRQLSSEKLM 449

Query: 261  EAAR--FEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEI----EEKG 314
            +  +   ++ L+ S+L ++L++                +Q  E    +++      E + 
Sbjct: 450  DKEQQVADLQLKLSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQQSTTAKLREAQN 509

Query: 315  SLE--IANMTELTKKIELLEHL------NCQIRQTNKE-LENKLATMGTESKAVSSPSKK 365
             LE  +  + +  +KI+ LE L      N  + +  +E L  K+     E+  ++   +K
Sbjct: 510  DLEQVLRQIGDKDQKIQNLEALLQKSKENISLLEKEREDLYAKIQAGEGETAVLNQLQEK 569

Query: 366  GSPLISR-----KSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKD 420
               L  +     +  +N +   K     L  +   Q    +  ++ +  LE  +  LN  
Sbjct: 570  NHTLQEQVTQLTEKLKNQSESHKQAQENLHDQVQEQKAHLRAAQDRVLSLETSVNELNSQ 629

Query: 421  LVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAK 480
            L + +  +S+ D             +      + + Q H++  +   +    +++N+I  
Sbjct: 630  LNESKEKVSQLDIQIKAKTELLLSAEAAKTAQRADLQNHLD-TAQNALQDKQQELNKITT 688

Query: 481  VQEQLKQELNDEIK-----DVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKL 535
              +Q+  +L D+ +     + ++K+  EK  S E++  +L  +I     + ++VK++ + 
Sbjct: 689  QLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQIKKLEADSLEVKASKEQ 748

Query: 536  KLKQMQK----------TIDNFSKVSDSNKEIVRLT--------EELHHLSQKVAELEEE 577
             L+ +Q+               SK  +  KEIV  T        E L  + QK+ + EEE
Sbjct: 749  ALQDLQQQRQLNTDLELRATELSKQLEMEKEIVSSTRLDLQKKSEALESIKQKLTKQEEE 808

Query: 578  KGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKY 637
            K   Q+   D+++   +  +   +  E+ N  +T +  +  ++ +K  L+ EL  ++ K 
Sbjct: 809  K---QILKQDFET---LSQETKIQHEELNNRIQTTVTELQKVKMEKEALMTELSTVKDKL 862

Query: 638  DEVEDKLADI-SQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTI 696
             +V D L +  S+ + +    +   + LE+    L   K +L + +EN   ++++L    
Sbjct: 863  SKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKEL---KHQLQVQMENTLKEQKELK--- 916

Query: 697  KDLENDKE-DIMNKLQ-NYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGID 754
            K LE +KE     KL+ N +QE +       K + ++  +L   IN  +QS  Q +  I+
Sbjct: 917  KSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQLQGNINELKQSSEQKKKQIE 976

Query: 755  AKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYS 814
            A   E  + +       +K + ++ +  + +A  +++   L+   ++     ++ Q   S
Sbjct: 977  ALQGELKIAVLQKTELENKLQQQLTQAAQELAAEKEKISVLQNNYEKSQETFKQLQ---S 1033

Query: 815  EYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQ 874
            ++  +E EL   LA   D   V EK  L +  E+  +  +NQI    NQN    L    +
Sbjct: 1034 DFYGRESEL---LATRQDLKSVEEK--LSLAQEDL-ISNRNQI---GNQN---KLIQELK 1081

Query: 875  HYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKK--EIEDLEIEF 932
               A +E+    D A+ E  + Q + + L+   K  + + + L+ +K K  EIE+++   
Sbjct: 1082 TAKATLEQ----DSAKKEQ-QLQERCKALQDIQKEKSLKEKELVNEKSKLAEIEEIKCRQ 1136

Query: 933  N---TQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQ-EYKNNIENLNMNVEELNKMNLEL 988
                T++   ++  K+ + K   N++   QL  Q + E +   ++L   VE+  K N ++
Sbjct: 1137 EKEITKLNEELKSHKLESIKEITNLKDAKQLLIQQKLELQGKADSLKAAVEQ-EKRNQQI 1195

Query: 989  IDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYES 1048
            +   V+K++    +  +++I +  KL++ +K+K  E+     + N A+++    ++    
Sbjct: 1196 LKDQVKKEE---EELKKEFIEKEAKLHSEIKEK--EVGMKKHEENEAKLT--MQITALNE 1248

Query: 1049 KLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPK 1108
             L     + ++ +  +  + KQ  D +     L+  V+   D+ + L E  L  E  I K
Sbjct: 1249 NLGTVKKEWQSSQRRVSELEKQTDDLRGEIAVLEATVQNNQDERRALLERCLKGEGEIEK 1308

Query: 1109 TEGMII 1114
             +  ++
Sbjct: 1309 LQTKVL 1314



 Score = 89.8 bits (213), Expect = 5e-16
 Identities = 148/785 (18%), Positives = 332/785 (42%), Gaps = 64/785 (8%)

Query: 146  HLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXX 205
            +L + ++E+   L   Q ++  +ET++ +L  ++NE  + +   +               
Sbjct: 597  NLHDQVQEQKAHLRAAQDRVLSLETSVNELNSQLNESKEKVSQLDIQIKAKTELLLSAEA 656

Query: 206  XXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARF 265
                   D +  +   Q    A++ + + E  ++   ++    ++   +E    LE+   
Sbjct: 657  AKTAQRADLQNHLDTAQN---ALQ-DKQQELNKITTQLDQVTAKLQDKQEHCSQLESHLK 712

Query: 266  EISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELT 325
            E   ++  L Q+ E+              + K S E + ++  +  +  +      TEL+
Sbjct: 713  EYKEKYLSLEQKTEELEGQIKKLEADSLEV-KASKEQALQDLQQQRQLNTDLELRATELS 771

Query: 326  KKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSP 385
            K++E+ + +   +  T  +L+ K       S+A+ S  +K   L  ++  +     +K  
Sbjct: 772  KQLEMEKEI---VSSTRLDLQKK-------SEALESIKQK---LTKQEEEKQI---LKQD 815

Query: 386  WSQLSSETLNQDTDKKINKNEI-AKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXG 444
            +  LS ET       KI   E+  +++  +  L K  ++KE +++E  T           
Sbjct: 816  FETLSQET-------KIQHEELNNRIQTTVTELQKVKMEKEALMTELSTVKDKLSKVSDS 868

Query: 445  KDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAK-VQEQLKQELNDEIKDVNVKDLIE 503
                 ++ + E+Q   +G + I       D+ +  K ++ QL+ ++ + +K+   K+L +
Sbjct: 869  LKNSKSEFEKENQ---KGKAAI------LDLEKTCKELKHQLQVQMENTLKE--QKELKK 917

Query: 504  KLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEE 563
             L+  +E   QL  E+++  + +I+ ++  K   K+ Q+   N +++  S+++  +  E 
Sbjct: 918  SLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQLQGNINELKQSSEQKKKQIEA 977

Query: 564  LH-HLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQ 622
            L   L   V +  E +  LQ  L         E +   K+  ++N  E   +    L+S 
Sbjct: 978  LQGELKIAVLQKTELENKLQQQLTQAAQELAAEKE---KISVLQNNYEKSQETFKQLQSD 1034

Query: 623  KFDLVQELHILQQKYDEVEDKLADISQ---LQSDQVCSEIKSVHLEEQIDAL---SASKK 676
             +    EL   +Q    VE+KL+   +      +Q+ ++ K +   +   A     ++KK
Sbjct: 1035 FYGRESELLATRQDLKSVEEKLSLAQEDLISNRNQIGNQNKLIQELKTAKATLEQDSAKK 1094

Query: 677  ELALVIENLKLDKEQLYGTIKDLE--NDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISE 734
            E  L      L   Q   ++K+ E  N+K  +    +   ++  ++T   E++ + K+  
Sbjct: 1095 EQQLQERCKALQDIQKEKSLKEKELVNEKSKLAEIEEIKCRQEKEITKLNEELKSHKLES 1154

Query: 735  L--LAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRR 792
            +  +  +   +Q  IQ +  +  K       +E  +      K ++ + EE +     ++
Sbjct: 1155 IKEITNLKDAKQLLIQQKLELQGKADSLKAAVEQEKRNQQILKDQVKKEEEEL-----KK 1209

Query: 793  YSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQ 852
              +E++A +L S ++EK+    ++   E +L  ++  L ++   V+K+    +    EL+
Sbjct: 1210 EFIEKEA-KLHSEIKEKEVGMKKHEENEAKLTMQITALNENLGTVKKEWQSSQRRVSELE 1268

Query: 853  KKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITH 912
            K+   L  E   L+ ++ + Q    AL+E+  +    E E  K QT++ +L+  L   T 
Sbjct: 1269 KQTDDLRGEIAVLEATVQNNQDERRALLERCLK---GEGEIEKLQTKVLELQRKLDNTTA 1325

Query: 913  EHQTL 917
              Q L
Sbjct: 1326 AVQEL 1330



 Score = 52.4 bits (120), Expect = 1e-04
 Identities = 102/550 (18%), Positives = 220/550 (40%), Gaps = 50/550 (9%)

Query: 1047 ESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEEL-QILVREQDDQIKELKETKLTFEMN 1105
            ES LA     +  + +E+Q +   L + K ++EEL + L + Q  Q +E K   L  + +
Sbjct: 75   ESNLALKRDDVTLLRQEVQDLQASLKEEKWYSEELKKELEKYQGLQQQEAKPDGLVTDSS 134

Query: 1106 --IPKTEGMIISSTIEPMS----DDANNVDXXXXXXXXXXXXLKVQEE----EEFIQERS 1155
              +   E  +  +  E  +     D                  K  EE    E   Q+ +
Sbjct: 135  AELQSLEQQLEEAQTENFNIKQMKDLFEQKAAQLATEIADIKSKYDEERSLREAAEQKVT 194

Query: 1156 VLQEQSAKLNTELQECYTKIIQ-------------LETLNTELTGHDVVNQEQINQLKSK 1202
             L E+  K  T +Q+  T+++Q             L  + T +    +  + +  +LK +
Sbjct: 195  RLTEELNKEATVIQDLKTELLQRPGIEDVAVLKKELVQVQTLMDNMTLERERESEKLKDE 254

Query: 1203 LEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLS 1262
             ++L ++  +  +T+++LRS ++    +    + EL  Q L     +  +    L   L 
Sbjct: 255  CKKLQSQYASSEATISQLRSELAKGPQEVAVYVQEL--QKLKSSVNELTQKNQTLTENLL 312

Query: 1263 AFESKYEQLLDSVQSSTQEETNKIVTMEQ----VTSLQNKLQDKEEHLRNLQEKYADVIN 1318
              E  Y +L +     +  + N   T+ Q       LQ++L   E  L  +  + ++   
Sbjct: 313  KKEQDYTKLEEKHNEESVSKKNIQATLHQKDLDCQQLQSRLSASETSLHRIHVELSEKGE 372

Query: 1319 QIEILRSEIEDEKVAFXXXXX------XXXXXXXXXXXDLRTE-NQSYKQMQEQSILNIN 1371
              + L+ E+ + +  +                       L++E NQ + ++ E     + 
Sbjct: 373  ATQKLKEELSEVETKYQHLKAEFKQLQQQREEKEQHGLQLQSEINQLHSKLLETE-RQLG 431

Query: 1372 EENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRN 1431
            E + +LK+              +V D + K+  L  QL+ K +   +  H+   T  Q  
Sbjct: 432  EAHGRLKEQRQLSSEKLMDKEQQVADLQLKLSRLEEQLKEKVTNSTELQHQLDKTKQQHQ 491

Query: 1432 DE---FENVRQQLVEYEKRIEDLTY---EKESELAILRLKMHENANHYETMQKESEIERV 1485
            ++    ++   +L E +  +E +     +K+ ++  L   + ++  +   ++KE E    
Sbjct: 492  EQQALQQSTTAKLREAQNDLEQVLRQIGDKDQKIQNLEALLQKSKENISLLEKERE---- 547

Query: 1486 KLIEELNVKITESVSLNKQVAELNKALEEEVAK-TNEMQTALENQEIEIVTLNDEITNLQ 1544
             L  ++     E+  LN Q+ E N  L+E+V + T +++   E+ +     L+D++   +
Sbjct: 548  DLYAKIQAGEGETAVLN-QLQEKNHTLQEQVTQLTEKLKNQSESHKQAQENLHDQVQEQK 606

Query: 1545 NMVRASSSKI 1554
              +RA+  ++
Sbjct: 607  AHLRAAQDRV 616


>UniRef50_Q09EF7 Cluster: Putative uncharacterized protein; n=8;
            Caenorhabditis|Rep: Putative uncharacterized protein -
            Caenorhabditis elegans
          Length = 1911

 Score =  131 bits (316), Expect = 2e-28
 Identities = 245/1223 (20%), Positives = 511/1223 (41%), Gaps = 112/1223 (9%)

Query: 455  EHQQHMEGPSLI-HVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQIT 513
            ++ +H   P ++ H   +  D+     V E+   EL  ++K+   K+    L+   E + 
Sbjct: 93   DYGRHRSSPRVLAHYNLDGADIG----VGEENLDELFAKLKEELFKN--NTLEEVNEMLR 146

Query: 514  QLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAE 573
            + ND   AAN+++    +N   +L+Q+Q+     S    S     R   E  H  +K+  
Sbjct: 147  EENDAALAANEHLRVDATNLSRQLQQLQQQQHTESMRFRSENTRYRNQTETQH--RKLIS 204

Query: 574  LEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHIL 633
            L +E   ++  L  ++      +D+ +++ E    A    KAI   E +  D  Q+  + 
Sbjct: 205  LWKEFTAVKRQL--HELRTTTANDLDRQLTEFTRCATLMRKAIRHAEQKNLD--QKEQMK 260

Query: 634  QQKYDEVEDKLADISQLQSDQVCSEIKS-------VHLEEQIDALSASKKELALVIENLK 686
            ++K D +++ L  ++ +  + + SE K+          E++   L     EL+ ++E L 
Sbjct: 261  REKDDVLDETLRQLNSVTENYMKSEEKANERQRDLKRKEDECRKLREQNDELSDILEQLS 320

Query: 687  LDKEQLYGTIKDLENDKEDIMNKLQNYI-QENMDLTDKLEKMSAEKISELLAKINHEEQS 745
                ++ G  +       D+  K++  +  +N ++ +  E     +     AK + E++ 
Sbjct: 321  KMAHEMAGG-RGRNETPMDVARKMRKLLTTKNGEIDESREAAKQAEKERDRAKKDLEKEE 379

Query: 746  KIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSY 805
            K + +   +A+ +   +Y +  E +L K    + +  E I  +E++R S E+    + + 
Sbjct: 380  K-RRKDDREAERKRSSVYSQR-EHDLKKLDDELRKASEKIRNLEEQRESQEKLTISVQNS 437

Query: 806  LQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHE-----NKELQKKNQILLE 860
            L E  + + ++   E+ ++     L + +   E+ L   + E      KE  ++ +I  E
Sbjct: 438  LNEAHRQHKQFI--EELMIRHREELKEREDSHEEALRSKDTEERSRFEKERSEREKIRRE 495

Query: 861  --ENQNLQISL-SDMQQHYNALVEKANRTDLAESE----STKYQTQLRDLESNLKRITHE 913
              E +  Q SL  D+      L +K  R D+ E+E      K +T+    +     I   
Sbjct: 496  SDELRETQRSLKGDVAAMKTDLDDKTLRLDMLETERDELKKKLETEREQADQRDLEIAEC 555

Query: 914  HQTL--IVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNI 971
               L  + +K+ E+     EF   I +   + K+  E++ ++   +  L  Q++   + +
Sbjct: 556  RAKLDEMAEKEAELRKELAEFQAIITAMEGEGKLNQEQFLESKNELNTLTDQIESLNSEV 615

Query: 972  ENLNMNVEELNKMNLELIDKHVQKQQTQSPDYT---EQYINEINKLNALLKQKDEEIIAL 1028
            EN N  +  L    L+  + H+Q  +T S   T   E+   EI+ L A L +  E++   
Sbjct: 616  ENKNEEIRNL-MATLQEKEVHIQNVRTSSHQLTATYEEANGEIDILKAELTRLHEQVNER 674

Query: 1029 NQKINNAQVSYMSMVSDYESKLAQFTT---KLENMEEEMQRVSKQLLDSKQHNEELQILV 1085
             ++I+ A   Y       ++ L    T   K E ++ E++ ++++  + ++   +L+ L+
Sbjct: 675  TRQISEANEKYDDAARKNDALLEDVATWQEKYEQLKMELEEMNRRGQEKEREEADLRALL 734

Query: 1086 REQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMS---DDANNVDXXXXXXXXXXXXL 1142
                D ++     KLT E+   K +G+ + S  E +S   +  N  +            L
Sbjct: 735  ----DDLRG-NFDKLTNEL---KQKGVTVDSLNEEISSLKEQLNKSEKERKEELLRMEEL 786

Query: 1143 KVQEEEEFIQERSVLQEQSAKLNTELQ----ECYTKIIQLETLNTEL-TGHDVV------ 1191
            + + E E  +E  V  + + K    ++    EC  ++ +L  ++  L   HD +      
Sbjct: 787  EQKNEAEMKEEYEVKLQLAEKDRQGVENFGKECEARMNELTKIHEMLMEEHDQLKVDHLH 846

Query: 1192 NQEQINQLKSK----LEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQRE 1247
             +E++ +LK K    LE+LN +ND   +  +  R+ + S+ ++   E+ E   Q L    
Sbjct: 847  TEEEVERLKEKMRKELEKLNEQNDGDRAEWSNERNRLESSKNEAVTELQER-VQKLEDVV 905

Query: 1248 ADFQKTEHELRVQLSAFESKYEQLLDSVQSS--TQEETNKIVTMEQVTSLQN--KLQDKE 1303
             + +  E  LR  L     K   L D ++    T EE  +    EQ T  +   KL +++
Sbjct: 906  KEKEDKEIALRRDLEDSHEKSRDLDDKLRKMELTDEEKEEDRKKEQKTLNEERMKLMEQK 965

Query: 1304 EHLRNLQEKYADVINQ----IEILRSEIEDEKVAFX---XXXXXXXXXXXXXXXDLRTEN 1356
            E    +  K+A  I+Q    I +L  ++E                          L T  
Sbjct: 966  EEAMLVATKHATTIDQQTRRISVLEGDVEKLTAGIAERESSINALESNTMELISKLETTE 1025

Query: 1357 QSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLE---LTHQLELKD 1413
               ++++++  + + ++N++LK               ++ D   ++ E   + H + +K+
Sbjct: 1026 AELEKLKDELAVML-KQNSELKNGKEGLSEKWNEERKKIQDLADQLREANKVVHNMRMKN 1084

Query: 1414 SEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIE---DLTYEKESEL-AILRLKMHE- 1468
              + +K +E    +T   ++   +  QL++   + E   DL  + E +  ++L+   +E 
Sbjct: 1085 VNLEEKKNELDQNVTDLTNKVRQLEIQLMDKAAKNEVSGDLLRKMEHDAQSMLKQAQNEQ 1144

Query: 1469 -NANHYETMQKESEIERVKLIEEL-NVKITESVSLNKQVAELNKALE-----EEVAKTNE 1521
                  E ++K  + E  +L+ +L  VK    V      + ++  L+     EE A   E
Sbjct: 1145 FRLTDLEKVRKALQDENQRLVNDLATVKAAFEVKRETSKSAISDILDKYRSAEEKANKGE 1204

Query: 1522 MQTALENQEIEIVTLNDEITNLQ-----NMVRASSSKIQKHVSFASDTKQGRDEQLDNTM 1576
            +       ++  VTL  E   L+     N +R S  + ++  S  ++ ++   E L N M
Sbjct: 1205 LDNQRLRSDLATVTLKLERQELKAKDSDNRLRDSQKRFEEVQSKLANLQKSAVESLQNPM 1264

Query: 1577 ------NKELLDAVPRAELDLAM 1593
                  N+ +   +PRA   + +
Sbjct: 1265 SSNSRQNRSIYVDIPRAASSIGL 1287



 Score =  113 bits (271), Expect = 5e-23
 Identities = 277/1504 (18%), Positives = 606/1504 (40%), Gaps = 126/1504 (8%)

Query: 140  QLGDVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXX 199
            QL  VT   N +K ++ A +  Q  +K  E     L+E+ +E   I+E  +K        
Sbjct: 273  QLNSVTE--NYMKSEEKA-NERQRDLKRKEDECRKLREQNDELSDILEQLSKMAHEMAGG 329

Query: 200  XXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQR--LLKDIESKDVRISSLEEAN 257
                        +  K   TK  E   + EA  + EK+R    KD+E ++ R     EA 
Sbjct: 330  RGRNETPMDVARKMRKLLTTKNGEIDESREAAKQAEKERDRAKKDLEKEEKRRKDDREAE 389

Query: 258  KLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLE 317
            +   +   +   +  KL  EL +               A + I  + EE+ E +EK ++ 
Sbjct: 390  RKRSSVYSQREHDLKKLDDELRK---------------ASEKIR-NLEEQRESQEKLTIS 433

Query: 318  IAN-MTELTKKI-ELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSG 375
            + N + E  ++  + +E L  + R+  KE E+        SK     S+       R+  
Sbjct: 434  VQNSLNEAHRQHKQFIEELMIRHREELKEREDSHEE-ALRSKDTEERSRFEKERSEREKI 492

Query: 376  RNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXX 435
            R  + +++     L  +     TD       +  LE     L K L  +     ++D   
Sbjct: 493  RRESDELRETQRSLKGDVAAMKTDLDDKTLRLDMLETERDELKKKLETEREQADQRDLEI 552

Query: 436  XXXXXXXXGKDTLIAQLQLEHQQH------MEGPSLIHVGTNTEDVNEIAKVQEQLKQEL 489
                          A+L+ E  +       MEG   ++     E  NE+  + +Q+ + L
Sbjct: 553  AECRAKLDEMAEKEAELRKELAEFQAIITAMEGEGKLNQEQFLESKNELNTLTDQI-ESL 611

Query: 490  NDEIKDVN--VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNF 547
            N E+++ N  +++L+  L+  E  I   N    +        ++N ++ + + + T  + 
Sbjct: 612  NSEVENKNEEIRNLMATLQEKEVHIQ--NVRTSSHQLTATYEEANGEIDILKAELTRLH- 668

Query: 548  SKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMEN 607
             +V++  ++I    E+    ++K   L E+    Q     Y+  +M   ++ ++  E E 
Sbjct: 669  EQVNERTRQISEANEKYDDAARKNDALLEDVATWQ---EKYEQLKMELEEMNRRGQEKER 725

Query: 608  LAETRLKAISLLESQKFD-LVQELHILQQKYDEVEDKLADIS-QLQSDQVCSEIKSVHLE 665
              E  L+A+       FD L  EL       D + ++++ +  QL   +   + + + +E
Sbjct: 726  -EEADLRALLDDLRGNFDKLTNELKQKGVTVDSLNEEISSLKEQLNKSEKERKEELLRME 784

Query: 666  EQIDALSAS-KKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKL 724
            E      A  K+E  + ++  + D++ +    K+ E    ++  K+   + E  D     
Sbjct: 785  ELEQKNEAEMKEEYEVKLQLAEKDRQGVENFGKECEARMNEL-TKIHEMLMEEHDQLKVD 843

Query: 725  EKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESE-LSKYKSRICRLEE 783
               + E++  L  K+  E +   +   G  A+       +E+ ++E +++ + R+ +LE+
Sbjct: 844  HLHTEEEVERLKEKMRKELEKLNEQNDGDRAEWSNERNRLESSKNEAVTELQERVQKLED 903

Query: 784  SIAVMEDRRYSLERKAD---QLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQ 840
             +   ED+  +L R  +   +    L +K +       +++E   +    ++ +R+   +
Sbjct: 904  VVKEKEDKEIALRRDLEDSHEKSRDLDDKLRKMELTDEEKEEDRKKEQKTLNEERM---K 960

Query: 841  LLEIEHENKELQKKNQILLEEN-QNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQ 899
            L+E + E   +  K+   +++  + + +   D+++    + E+ +  +  ES + +  ++
Sbjct: 961  LMEQKEEAMLVATKHATTIDQQTRRISVLEGDVEKLTAGIAERESSINALESNTMELISK 1020

Query: 900  LRDLESNLKRITHEHQTLIVQK---KKEIEDLEIEFNTQ------IESAIRD-KKVLNEK 949
            L   E+ L+++  E   ++ Q    K   E L  ++N +      +   +R+  KV++  
Sbjct: 1021 LETTEAELEKLKDELAVMLKQNSELKNGKEGLSEKWNEERKKIQDLADQLREANKVVHNM 1080

Query: 950  YEKNI---EYVTQLEAQLQEYKNNIENLNMNVEEL---NKMNLELIDKHVQKQQTQSPD- 1002
              KN+   E   +L+  + +  N +  L + + +    N+++ +L+ K     Q+     
Sbjct: 1081 RMKNVNLEEKKNELDQNVTDLTNKVRQLEIQLMDKAAKNEVSGDLLRKMEHDAQSMLKQA 1140

Query: 1003 YTEQY-INEINKLNALLKQKDEEII----ALNQKINNAQVSYMSMVSDYESKLAQFTTKL 1057
              EQ+ + ++ K+   L+ +++ ++     +       + +  S +SD   K      K 
Sbjct: 1141 QNEQFRLTDLEKVRKALQDENQRLVNDLATVKAAFEVKRETSKSAISDILDKYRSAEEKA 1200

Query: 1058 ENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISST 1117
               E + QR+   L       E  ++  ++ D+++++ ++     +  +   +   + S 
Sbjct: 1201 NKGELDNQRLRSDLATVTLKLERQELKAKDSDNRLRDSQKRFEEVQSKLANLQKSAVESL 1260

Query: 1118 IEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQ 1177
              PMS ++                + + E  + +  RS    + A  +  +Q     +  
Sbjct: 1261 QNPMSSNSRQNRSIYVDIPRAASSIGLNENSDEVPLRSSPSVRFADSSQNMQRAVDSMDV 1320

Query: 1178 LETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAE 1237
              ++   L             LK ++EQL  +N       A+L  ++  A D    E+ +
Sbjct: 1321 SSSVGVTL-----------RFLKERIEQLEADN-------ADLSDALEKAKD----ELRQ 1358

Query: 1238 LWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSS--TQEETNKIVTMEQVTSL 1295
               + LA R+   ++ E +L V ++   +  E  + S +    T EE+++    E + S+
Sbjct: 1359 R-NEKLADRQMVIERVERQL-VHITEERNTIENRMTSQRQMYLTNEESSRSREHE-IRSM 1415

Query: 1296 QNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTE 1355
            + ++   E HLR  + K A +  +IE+L  ++ D  +                  DL  +
Sbjct: 1416 KARISTLELHLREKESKLAHLRKEIEVLHGQLHD-ALESKEKATGLVGVQDSKHRDLEEQ 1474

Query: 1356 NQSYKQMQEQSI---LNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELK 1412
                 + +E +I        EN  L +               + D E ++ E  ++  L+
Sbjct: 1475 LDRANRERELAIGKQRRTLAENENLFRKLEQLEKEREQLMREITD-ERRLNE-RNRTSLE 1532

Query: 1413 DSEIYQKTHEYTITLTQR-NDEFENVRQQLVEYEKRIEDLTYEKES---ELAILRLKMHE 1468
            +  + ++T +  +T  ++  +E E   Q+   +E+   ++T    +   E   LR++M +
Sbjct: 1533 ELRVSERTWKSAMTTAKKPAEEQERAVQEQRRWEESNHEMTNRNTALTKECDRLRVEMRD 1592

Query: 1469 NANHYETMQKESEIERVKLIEELNVKI---TESVSLNKQVAELNKALEEE-------VAK 1518
              N    +   S ++  +  EEL+ K+     +V+  K+  E  K LE E       + K
Sbjct: 1593 QLNRMNGINLRS-VDFERKNEELSSKLIVMQNTVTAMKKFEEEWKRLEAEMRAELKILRK 1651

Query: 1519 TNEMQTA----LENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDN 1574
               MQTA    L+ +     T   EI  ++  +    S +++HV    + K   ++ +  
Sbjct: 1652 EKLMQTAEIEDLKRKSFRSDTEKKEIEGIRVRLEREISALKRHVDALEEEKGKTEKAVRE 1711

Query: 1575 TMNK 1578
            TMN+
Sbjct: 1712 TMNE 1715



 Score = 96.7 bits (230), Expect = 5e-18
 Identities = 222/1224 (18%), Positives = 499/1224 (40%), Gaps = 95/1224 (7%)

Query: 147  LSNTIKEKDNALSVLQVKMKIMETTILDLQEKI---NEKDQIIEAKNKATTXXXXXXXXX 203
            L+ T +E +  + +L+ ++  +   + +   +I   NEK      KN A           
Sbjct: 646  LTATYEEANGEIDILKAELTRLHEQVNERTRQISEANEKYDDAARKNDALLEDVATWQEK 705

Query: 204  XXXXXXXXEDTK---QQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLL 260
                    E+     Q+  + + +  A+  + +    +L  +++ K V + SL E    L
Sbjct: 706  YEQLKMELEEMNRRGQEKEREEADLRALLDDLRGNFDKLTNELKQKGVTVDSLNEEISSL 765

Query: 261  EAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIAN 320
            +    +   E  +    +E+              +  Q  E   +++  +E  G    A 
Sbjct: 766  KEQLNKSEKERKEELLRMEELEQKNEAEMKEEYEVKLQLAE---KDRQGVENFGKECEAR 822

Query: 321  MTELTKKIELLEHLNCQIR----QTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGR 376
            M ELTK  E+L   + Q++     T +E+E     M  E + ++  +       S +  R
Sbjct: 823  MNELTKIHEMLMEEHDQLKVDHLHTEEEVERLKEKMRKELEKLNEQNDGDRAEWSNERNR 882

Query: 377  NTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXX 436
              +SK ++           +D  K+    EIA L   ++  ++   D +  + + +    
Sbjct: 883  LESSKNEAVTELQERVQKLEDVVKEKEDKEIA-LRRDLEDSHEKSRDLDDKLRKMELTDE 941

Query: 437  XXXXXXXGKDTLIAQLQLEHQQHMEGPSLI---HVGTNTEDVNEIAKVQ---EQL----- 485
                    +   + + +++  +  E   L+   H  T  +    I+ ++   E+L     
Sbjct: 942  EKEEDRKKEQKTLNEERMKLMEQKEEAMLVATKHATTIDQQTRRISVLEGDVEKLTAGIA 1001

Query: 486  KQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHK---LKLKQMQK 542
            ++E +    + N  +LI KL++ E ++ +L DE+    K   ++K+  +    K  + +K
Sbjct: 1002 ERESSINALESNTMELISKLETTEAELEKLKDELAVMLKQNSELKNGKEGLSEKWNEERK 1061

Query: 543  TIDNFS-KVSDSNKEI-------VRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMI 594
             I + + ++ ++NK +       V L E+ + L Q V +L  +   L++ L+D  +   +
Sbjct: 1062 KIQDLADQLREANKVVHNMRMKNVNLEEKKNELDQNVTDLTNKVRQLEIQLMDKAAKNEV 1121

Query: 595  ESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQ 654
              D+ +KM   E+ A++ LK     + +  DL +    LQ +   + + LA +    + +
Sbjct: 1122 SGDLLRKM---EHDAQSMLKQAQNEQFRLTDLEKVRKALQDENQRLVNDLATVKA--AFE 1176

Query: 655  VCSEIKSVHLEEQIDAL-SASKKELALVIENLKLDKEQLYGTIKDLENDK---EDIMNKL 710
            V  E     + + +D   SA +K     ++N +L  +    T+K LE  +   +D  N+L
Sbjct: 1177 VKRETSKSAISDILDKYRSAEEKANKGELDNQRLRSDLATVTLK-LERQELKAKDSDNRL 1235

Query: 711  QNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESE 770
            ++  +   ++  KL  +    +  L   ++    S+      +D       + +     E
Sbjct: 1236 RDSQKRFEEVQSKLANLQKSAVESLQNPMS--SNSRQNRSIYVDIPRAASSIGLNENSDE 1293

Query: 771  LSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVL 830
            +    S   R  +S   M+    S++  +  +G  L+  ++   +      +L + L   
Sbjct: 1294 VPLRSSPSVRFADSSQNMQRAVDSMD-VSSSVGVTLRFLKERIEQLEADNADLSDALEKA 1352

Query: 831  MDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAE 890
             D  R   ++L + +   + ++++   + EE   ++  ++  +Q Y    E+++R+   E
Sbjct: 1353 KDELRQRNEKLADRQMVIERVERQLVHITEERNTIENRMTSQRQMY-LTNEESSRS--RE 1409

Query: 891  SESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKY 950
             E    + ++  LE +L+    E ++ +   +KEIE L  + +  +ES  +   ++  + 
Sbjct: 1410 HEIRSMKARISTLELHLR----EKESKLAHLRKEIEVLHGQLHDALESKEKATGLVGVQD 1465

Query: 951  EKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINE 1010
             K+ +   QL+   +E +  I      + E   +  +L     +++Q       E+ +NE
Sbjct: 1466 SKHRDLEEQLDRANRERELAIGKQRRTLAENENLFRKLEQLEKEREQLMREITDERRLNE 1525

Query: 1011 INKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQ 1070
             N+ +        E + ++++   + ++     ++ + +  Q   + E    EM   +  
Sbjct: 1526 RNRTSL-------EELRVSERTWKSAMTTAKKPAEEQERAVQEQRRWEESNHEMTNRNTA 1578

Query: 1071 LLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDX 1130
            L    +  + L++ +R+Q +++  +    + FE    K E   +SS +  M +    +  
Sbjct: 1579 L---TKECDRLRVEMRDQLNRMNGINLRSVDFER---KNEE--LSSKLIVMQNTVTAMKK 1630

Query: 1131 XXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDV 1190
                          + E E   E  +L+++      E+++   K  + +T   E+ G  V
Sbjct: 1631 FEEEWK--------RLEAEMRAELKILRKEKLMQTAEIEDLKRKSFRSDTEKKEIEGIRV 1682

Query: 1191 VNQEQINQLKSKLEQLNTENDNLLSTVAEL---RSSISSAVDQRGFEIAELWKQHLAQRE 1247
              + +I+ LK  ++ L  E       V E    R +I  ++     E  +L++ + AQ +
Sbjct: 1683 RLEREISALKRHVDALEEEKGKTEKAVRETMNERRAIDKSLASMERENQQLYR-NCAQLQ 1741

Query: 1248 ADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLR 1307
            A  Q  E +   +     +K   LL++  ++  EE        Q+ S+ ++      H R
Sbjct: 1742 AQIQNLERDAGNRSVTKLAKEHSLLEARIAALIEE------KRQLQSMLDQKDANYSHKR 1795

Query: 1308 NLQEKYADVINQIEILRSEIEDEK 1331
             L E      +QI++LR ++E E+
Sbjct: 1796 KLLE------SQIQLLREQLEAER 1813



 Score = 95.1 bits (226), Expect = 1e-17
 Identities = 259/1343 (19%), Positives = 542/1343 (40%), Gaps = 133/1343 (9%)

Query: 297  KQSIEPSCEEKTEIEEKGSLEIANM-TELTKKIELLEHLNCQIRQTNKELENKLATMGTE 355
            ++ I    +E  E +     ++A M T+L  K   L+ L  +  +  K+LE +       
Sbjct: 489  REKIRRESDELRETQRSLKGDVAAMKTDLDDKTLRLDMLETERDELKKKLETEREQADQR 548

Query: 356  SKAVSSPSKKGSPLISRKSG-RNTASKMKSPWSQLSSE-TLNQDTDKKINKNEIAKLEMV 413
               ++    K   +  +++  R   ++ ++  + +  E  LNQ+   + +KNE+  L   
Sbjct: 549  DLEIAECRAKLDEMAEKEAELRKELAEFQAIITAMEGEGKLNQEQFLE-SKNELNTLTDQ 607

Query: 414  IQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNT- 472
            I+SLN ++ +K   I                  T   QL   +++      ++       
Sbjct: 608  IESLNSEVENKNEEIRNLMATLQEKEVHIQNVRTSSHQLTATYEEANGEIDILKAELTRL 667

Query: 473  -EDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKS 531
             E VNE  +   +  ++ +D  +  +   L+E + + +E+  QL  E++  N+   + K 
Sbjct: 668  HEQVNERTRQISEANEKYDDAARKNDA--LLEDVATWQEKYEQLKMELEEMNRRG-QEKE 724

Query: 532  NHKLKLKQMQKTI-DNFSKVSDSNKE----IVRLTEELHHLSQKVAELEEEKGNLQLHLV 586
              +  L+ +   +  NF K+++  K+    +  L EE+  L +++ + E+E+    L + 
Sbjct: 725  REEADLRALLDDLRGNFDKLTNELKQKGVTVDSLNEEISSLKEQLNKSEKERKEELLRME 784

Query: 587  DYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLAD 646
            + +          K   EM+   E +L+   L E  +  +       + + +E+  K+ +
Sbjct: 785  ELEQ---------KNEAEMKEEYEVKLQ---LAEKDRQGVENFGKECEARMNELT-KIHE 831

Query: 647  ISQLQSDQVCSEIKSVHLEEQIDALSAS-KKELALVIENLKLDKEQLYGTIKDLENDKED 705
            +   + DQ+  ++  +H EE+++ L    +KEL  + E    D+ +       LE+ K +
Sbjct: 832  MLMEEHDQL--KVDHLHTEEEVERLKEKMRKELEKLNEQNDGDRAEWSNERNRLESSKNE 889

Query: 706  IMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIE 765
             + +LQ  +Q       KLE +  EK  + +A     E S  +++  +D K+++ +L  E
Sbjct: 890  AVTELQERVQ-------KLEDVVKEKEDKEIALRRDLEDSHEKSR-DLDDKLRKMELTDE 941

Query: 766  NIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVN 825
              E +  K +  +   EE + +ME +  ++   A +  + + ++ +  S      ++L  
Sbjct: 942  EKEEDRKKEQKTLN--EERMKLMEQKEEAM-LVATKHATTIDQQTRRISVLEGDVEKLTA 998

Query: 826  RLAVLMDHDRVVEKQLLEI-------EHENKELQKKNQILLEENQNLQISLSDMQQHYNA 878
             +A        +E   +E+       E E ++L+ +  ++L++N  L+     + + +N 
Sbjct: 999  GIAERESSINALESNTMELISKLETTEAELEKLKDELAVMLKQNSELKNGKEGLSEKWNE 1058

Query: 879  LVEKANRTDLAES--ESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQI 936
              E+    DLA+   E+ K    +R    NL+   +E    +     ++  LEI+     
Sbjct: 1059 --ERKKIQDLADQLREANKVVHNMRMKNVNLEEKKNELDQNVTDLTNKVRQLEIQ----- 1111

Query: 937  ESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQ 996
               + DK   NE    + + + ++E   Q      +N    + +L K+   L D++   Q
Sbjct: 1112 ---LMDKAAKNEV---SGDLLRKMEHDAQSMLKQAQNEQFRLTDLEKVRKALQDEN---Q 1162

Query: 997  QTQSPDYTEQYINEINKLNALLKQKD--EEIIALNQKINNAQVSYMSMVSDYESKLAQFT 1054
            +  +   T +   E+ +  +     D  ++  +  +K N  ++    + SD    LA  T
Sbjct: 1163 RLVNDLATVKAAFEVKRETSKSAISDILDKYRSAEEKANKGELDNQRLRSD----LATVT 1218

Query: 1055 TKLENMEEEMQRVSKQLLDSKQHNEELQI-LVREQDDQIKELKET-------KLTFEMNI 1106
             KLE  E + +    +L DS++  EE+Q  L   Q   ++ L+           +  ++I
Sbjct: 1219 LKLERQELKAKDSDNRLRDSQKRFEEVQSKLANLQKSAVESLQNPMSSNSRQNRSIYVDI 1278

Query: 1107 PKTE---GMIISSTIEPMSDD-----ANNVDXXXXXXXXXXXXLKVQEEEEFIQER-SVL 1157
            P+     G+  +S   P+        A++                V     F++ER   L
Sbjct: 1279 PRAASSIGLNENSDEVPLRSSPSVRFADSSQNMQRAVDSMDVSSSVGVTLRFLKERIEQL 1338

Query: 1158 QEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTV 1217
            +  +A L+  L++   ++ Q    N +L    +V +    QL    E+ NT  +N +++ 
Sbjct: 1339 EADNADLSDALEKAKDELRQR---NEKLADRQMVIERVERQLVHITEERNTI-ENRMTSQ 1394

Query: 1218 AELRSSISSAVDQRGFEIAELWKQ------HLAQREADFQKTEHELRV---QL-SAFESK 1267
             ++  +   +   R  EI  +  +      HL ++E+       E+ V   QL  A ESK
Sbjct: 1395 RQMYLTNEESSRSREHEIRSMKARISTLELHLREKESKLAHLRKEIEVLHGQLHDALESK 1454

Query: 1268 YEQL-LDSVQSSTQEETNKIV----------------TMEQVTSLQNKLQDKEEHLRNLQ 1310
             +   L  VQ S   +  + +                T+ +  +L  KL+  E+    L 
Sbjct: 1455 EKATGLVGVQDSKHRDLEEQLDRANRERELAIGKQRRTLAENENLFRKLEQLEKEREQLM 1514

Query: 1311 EKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNI 1370
             +  D     E  R+ +E+ +V+                   R   +  ++  E+S   +
Sbjct: 1515 REITDERRLNERNRTSLEELRVSERTWKSAMTTAKKPAEEQERAVQE--QRRWEESNHEM 1572

Query: 1371 NEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQR 1430
               N  L K              R+N    + ++     E K+ E+  K      T+T  
Sbjct: 1573 TNRNTALTKECDRLRVEMRDQLNRMNGINLRSVDF----ERKNEELSSKLIVMQNTVTAM 1628

Query: 1431 NDEFENVRQQLVEYEKRIEDLTYEKESELAILRLK-MHENANHYETMQKESEIERVKLIE 1489
              +FE   ++L E E R E     KE  +    ++ +   +   +T +KE E  RV+L  
Sbjct: 1629 K-KFEEEWKRL-EAEMRAELKILRKEKLMQTAEIEDLKRKSFRSDTEKKEIEGIRVRLER 1686

Query: 1490 ELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRA 1549
            E++       +L ++  +  KA+ E + +   +  +L + E E    N ++      ++A
Sbjct: 1687 EISALKRHVDALEEEKGKTEKAVRETMNERRAIDKSLASMERE----NQQLYRNCAQLQA 1742

Query: 1550 SSSKIQKHVSFASDTKQGRDEQL 1572
                +++     S TK  ++  L
Sbjct: 1743 QIQNLERDAGNRSVTKLAKEHSL 1765


>UniRef50_A0CGX1 Cluster: Chromosome undetermined scaffold_18, whole
            genome shotgun sequence; n=3; Paramecium tetraurelia|Rep:
            Chromosome undetermined scaffold_18, whole genome shotgun
            sequence - Paramecium tetraurelia
          Length = 2941

 Score =  131 bits (316), Expect = 2e-28
 Identities = 253/1404 (18%), Positives = 591/1404 (42%), Gaps = 129/1404 (9%)

Query: 217  QMTKMQENFIAMEAEWK-DEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLA 275
            ++ K+QEN   +E E + +++++  K    +++     ++    L++A +++ LE  K  
Sbjct: 418  KVRKVQENTNRLENEKQINQEEQFWKQKYEEEIE---KQKRGYSLDSAEYQL-LEQIKEN 473

Query: 276  QELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLN 335
            QEL                  +  ++    E  ++ E    +    + L  +I+ L+  N
Sbjct: 474  QELLSQINLMKNDFLQQELYNEMELKKKQAENNKLMEMQDQQEQQQSFLNFQIKDLQQKN 533

Query: 336  CQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLN 395
             +  +  ++L  KL     E + + +   + +  +  +   N   ++  P     ++   
Sbjct: 534  LENEKVKQDLLIKLQQNDKEMQRLKNTINQSN--LKPQQQDNYQIQLCEPLLIEKNKKQL 591

Query: 396  QDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTL-IAQLQL 454
            +  D+  +KN +   E +I+   +D ++K Y  S K             +  + I+QL+ 
Sbjct: 592  ESEDQLKDKN-LELQEKIIEL--QDELNKIYSESTKTRRNFTQKEIVDPEKAIRISQLEQ 648

Query: 455  EHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQ 514
            E+Q+       +      +++     ++E  ++ + + I    V DLI + +  +E    
Sbjct: 649  ENQK-------LQAQIKEKELQRKDDLKE-FQEMIGNGITQQKVVDLIAEKQKLQEHFRV 700

Query: 515  LNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSN--KEIVRLTEELHHLSQKVA 572
            L +++DA  +N I+++S  + K K++ K ++ F    +    +  + L +++++L  ++ 
Sbjct: 701  LQNKVDALQQNQIRLQSELQSKNKEL-KELEQFQGEQNQPYIQGQINLNDQINNLEAQLI 759

Query: 573  ELEEEKGNLQLHLVDYDSGRMIESDVYKKMI-------EMENLAETRLKAISLLESQKFD 625
              +++   L        S   ++  + ++         ++ NL+    + I +LE Q   
Sbjct: 760  LAKKQYQELLETSQQNSSPNGLKEKILQQQALIHDYENQINNLSNKIEQEIPILEGQLAT 819

Query: 626  LVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENL 685
              Q++ + +      E +  ++  L + Q      +    + +  L+   +EL L    L
Sbjct: 820  ANQQIQVAENDILNQEKRYNEL--LNNKQYLQNPDTQIPSDDLKKLTEKNQELNL---QL 874

Query: 686  KLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKIN---HE 742
            + +  +L   +   E  KE+I  K + Y     +L  +++++  ++I +   KIN    +
Sbjct: 875  QQNNRKLEVQLDIEEKLKEEISEKDREY-----NLAQQIQQIQQDQIKDQQQKINKMIDK 929

Query: 743  EQSKIQTQFGIDAKI-QERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQ 801
            EQ  +Q    + +KI Q+RD+ ++N + +    K  I +++E  + ++ ++   E     
Sbjct: 930  EQQLMQEIANLSSKINQQRDINVDNTKQDNQNNKDDIIQIQEDDSALKIKQLQEELNKVI 989

Query: 802  LGSYLQEKQ-KAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKN--QIL 858
              + L+  + +   +   + +EL  +   L      ++ Q+  +E      Q+ N  Q+ 
Sbjct: 990  NENVLKNNECQVLQKLKPENEELRAQQTQLYYQIVQLQNQIHNLESFKPSKQQDNDQQLT 1049

Query: 859  LEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLI 918
             E +    +++S +QQ    L     R  L E ++ + +   +  E N      +H   +
Sbjct: 1050 FETDPEKTLAISQLQQQIQQL-----RNQLQEIQNQRAEDLQKFKEINENGADQQHIIEL 1104

Query: 919  VQKKKEIEDLEIEFNTQIESAIRDKKVL-NEKYEKNIEYVTQLEAQLQE-YKNNIENLNM 976
             Q K+ +E        Q+++A++++ ++  +  +KN ++        +E +K  +ENLN 
Sbjct: 1105 FQSKQNLEQQLRNLQNQLDNALQEQILIQGQLIQKNKQFSEFCSNYNEEDFKKQLENLNQ 1164

Query: 977  NVEELNKMNLELIDKHVQKQQTQSPDYTEQYINE--INKLNALLKQKDEEIIALNQKINN 1034
             ++E  +  L+   ++ +  +  S + T     E  + + N + +Q+ +EI  ++Q+++N
Sbjct: 1165 IIQEQQEKLLQSKQQYQELLELTSQNLTPNGQKEKLLQQANQIHEQQ-QEIQLMHQQLDN 1223

Query: 1035 AQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKE 1094
                    +++Y+ K     T++  + E  Q +  Q     Q N+      +    +   
Sbjct: 1224 EVPKLQGALAEYKQKYNDSQTEIHLLMERYQNLLNQRSKQDQSND------KSFSTKNNN 1277

Query: 1095 LKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQER 1154
            L++T L+ +    K +     + I    DD N  +              +QE     QE 
Sbjct: 1278 LQDTNLSAQKYDDKND----QTNISDFQDDINRKNI-------------LQE-----QEI 1315

Query: 1155 SVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTE--NDN 1212
            +++ +Q  K ++EL++ + +I               +  ++I  LK+KL + NTE   + 
Sbjct: 1316 ALMHKQQEKFSSELEDLHKQI--------------SLKDQEILILKNKLAEGNTEFWKEE 1361

Query: 1213 LLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLL 1272
                  + + SI +       +I +  +Q+L     D Q+   +L  Q++  E++ ++ L
Sbjct: 1362 YTKLATQNKGSIKT-------QIQDSPEQYLI---VDLQQQSQKLINQIAEIEAERQEDL 1411

Query: 1273 DSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKV 1332
               Q   + +  K  ++ Q+ S   +LQ  +   R +Q +  D++ Q++  + +++D K+
Sbjct: 1412 RKFQKILENDGTKDNSVVQLFSENQQLQQSK---RQMQNQIDDLLQQLKD-QKDLQDSKM 1467

Query: 1333 A--FXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQ--LKKSSXXXXXXX 1388
                                 L+   + Y+Q+QEQ   N+     Q  L +++       
Sbjct: 1468 IQNLANQILELENQNQLLSKQLQQSKEQYQQLQEQLQANLTPNGLQEKLLQNTQIIHQQQ 1527

Query: 1389 XXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEY---E 1445
                   N  +  + E+T QL++ D    +K  E      ++      ++Q++ +    +
Sbjct: 1528 EQILALQNQIQTDIPEVTQQLQVADQN-QKKALEEARNWKEKYLNLLEIKQEIPKIQIDD 1586

Query: 1446 KRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLN--- 1502
              I+ +  E+  +     +K ++ AN  E   K    E+ KLI +   +I    S N   
Sbjct: 1587 NIIKQMNLEESQDYIQTLVKNYQKANEQEQQAKILINEQKKLINQYENQIEAQHSQNSDI 1646

Query: 1503 -KQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQ---NMVRASSSKIQKHV 1558
             K+ A LNK  E + ++   +  + + Q  E++ L ++    Q   N  +  + K  + V
Sbjct: 1647 IKENAILNKLTETQNSQIERLSKSNQAQSQEMIDLKNQQRQEQYWKNEYQKLALKYGEDV 1706

Query: 1559 SFASDTKQGRDEQLDNTMNKELLD 1582
            S  S  ++    Q+D  +  E ++
Sbjct: 1707 SNKSPNQEDLINQIDENIQVESIN 1730



 Score =  122 bits (295), Expect = 6e-26
 Identities = 245/1248 (19%), Positives = 545/1248 (43%), Gaps = 113/1248 (9%)

Query: 402  INKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGK-DTLIAQLQLEHQQHM 460
            + +N+I +L+  +QS NK+L + E    E++            + + L AQL L  +Q+ 
Sbjct: 708  LQQNQI-RLQSELQSKNKELKELEQFQGEQNQPYIQGQINLNDQINNLEAQLILAKKQYQ 766

Query: 461  EGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEID 520
            E        ++   + E    Q+ L  +  ++I +++ K + +++   E Q+   N +I 
Sbjct: 767  ELLETSQQNSSPNGLKEKILQQQALIHDYENQINNLSNK-IEQEIPILEGQLATANQQIQ 825

Query: 521  AANKNMIKVKSNHKLKLKQMQKTIDNFSKV-SDSNKEIVRLTEELH-HLSQKVAELE--- 575
             A  +++  +  +   L   Q   +  +++ SD  K++    +EL+  L Q   +LE   
Sbjct: 826  VAENDILNQEKRYNELLNNKQYLQNPDTQIPSDDLKKLTEKNQELNLQLQQNNRKLEVQL 885

Query: 576  --EEKGNLQLHLVD--YDSGRMIES-------DVYKKMIEMENLAETRLKAISLLESQKF 624
              EEK   ++   D  Y+  + I+        D  +K+ +M +  +  ++ I+ L S K 
Sbjct: 886  DIEEKLKEEISEKDREYNLAQQIQQIQQDQIKDQQQKINKMIDKEQQLMQEIANLSS-KI 944

Query: 625  DLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLE-EQIDALSASKKELALVIE 683
            +  +++++   K D   +K  DI Q+Q D    +IK +  E  ++   +  K     V++
Sbjct: 945  NQQRDINVDNTKQDNQNNK-DDIIQIQEDDSALKIKQLQEELNKVINENVLKNNECQVLQ 1003

Query: 684  NLKLDKE-------QLYGTIKDLENDKEDIMNKLQNYIQEN-MDLTDKLEKMSAEKISEL 735
             LK + E       QLY  I  L+N   ++ +   +  Q+N   LT + +      IS+L
Sbjct: 1004 KLKPENEELRAQQTQLYYQIVQLQNQIHNLESFKPSKQQDNDQQLTFETDPEKTLAISQL 1063

Query: 736  LAKINH--EEQSKIQTQFGIDA-KIQERDLYIENIESELSKYKSRICRLEESIAVMEDRR 792
              +I     +  +IQ Q   D  K +E +    + +  +  ++S+   LE+ +  ++++ 
Sbjct: 1064 QQQIQQLRNQLQEIQNQRAEDLQKFKEINENGADQQHIIELFQSKQ-NLEQQLRNLQNQL 1122

Query: 793  YSLERKADQLGSYLQEKQKAYSEY--TIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKE 850
             +  ++   +   L +K K +SE+     E++   +L  L    +  +++LL+ + + +E
Sbjct: 1123 DNALQEQILIQGQLIQKNKQFSEFCSNYNEEDFKKQLENLNQIIQEQQEKLLQSKQQYQE 1182

Query: 851  L-QKKNQILLEENQNLQI-----SLSDMQQHYNALVEKA-NRTDLAESESTKYQTQLRDL 903
            L +  +Q L    Q  ++      + + QQ    + ++  N     +    +Y+ +  D 
Sbjct: 1183 LLELTSQNLTPNGQKEKLLQQANQIHEQQQEIQLMHQQLDNEVPKLQGALAEYKQKYNDS 1242

Query: 904  ESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQ 963
            ++ +  +   +Q L+ Q+ K+ +  +  F+T+  + ++D               T L AQ
Sbjct: 1243 QTEIHLLMERYQNLLNQRSKQDQSNDKSFSTK-NNNLQD---------------TNLSAQ 1286

Query: 964  LQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDE 1023
              + KN+  N++   +++N+ N+ L ++ +     Q     E++ +E+  L+  +  KD+
Sbjct: 1287 KYDDKNDQTNISDFQDDINRKNI-LQEQEIALMHKQQ----EKFSSELEDLHKQISLKDQ 1341

Query: 1024 EIIALNQKINNAQVSYMSMVSDYESKLAQ----FTTKLENMEEEMQRVSKQLLDSKQHNE 1079
            EI+ L  K+      +     +Y     Q      T++++  E+   V  Q    K  N+
Sbjct: 1342 EILILKNKLAEGNTEFWK--EEYTKLATQNKGSIKTQIQDSPEQYLIVDLQQQSQKLINQ 1399

Query: 1080 ELQILVREQDD--QIKELKETKLTFEMNIPK--TEGMIISSTIEPMSDDANNVDXXXXXX 1135
              +I    Q+D  + +++ E   T + ++ +  +E   +  +   M +  +++       
Sbjct: 1400 IAEIEAERQEDLRKFQKILENDGTKDNSVVQLFSENQQLQQSKRQMQNQIDDLLQQLKDQ 1459

Query: 1136 XXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQL-ETLNTELTGHDVVNQE 1194
                    +Q     I E   L+ Q+  L+ +LQ+   +  QL E L   LT + +  QE
Sbjct: 1460 KDLQDSKMIQNLANQILE---LENQNQLLSKQLQQSKEQYQQLQEQLQANLTPNGL--QE 1514

Query: 1195 QINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTE 1254
            ++ Q    + Q   + + +L+   ++++ I     Q   ++A+   Q  A  EA   K +
Sbjct: 1515 KLLQNTQIIHQ---QQEQILALQNQIQTDIPEVTQQ--LQVADQ-NQKKALEEARNWKEK 1568

Query: 1255 HELRVQLSAFESKYEQLLDSV--QSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEK 1312
            +   +++     K  Q+ D++  Q + +E  + I T+ +     N+ + + + L N Q+K
Sbjct: 1569 YLNLLEIKQEIPKI-QIDDNIIKQMNLEESQDYIQTLVKNYQKANEQEQQAKILINEQKK 1627

Query: 1313 YADVI-NQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNIN 1371
              +   NQIE   S+  D  +                   L   NQ+    Q Q ++++ 
Sbjct: 1628 LINQYENQIEAQHSQNSDI-IKENAILNKLTETQNSQIERLSKSNQA----QSQEMIDLK 1682

Query: 1372 EENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLE--LKDSEIYQKTHEYTITLTQ 1429
             +  Q +                V++      +L +Q++  ++   I +  ++  +   Q
Sbjct: 1683 NQQRQEQYWKNEYQKLALKYGEDVSNKSPNQEDLINQIDENIQVESINELKNQNDLLQQQ 1742

Query: 1430 RNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIE 1489
              D+ E ++   ++++   E L   +     +L  ++ +     E++Q +++ ++   + 
Sbjct: 1743 LIDQIEELKLTKIKFQ---EQLLQAQRQINDLLNNQIPQPTQSQESIQFQNDPQKALQLS 1799

Query: 1490 ELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALEN--QEIEIVTLNDEITNLQNMV 1547
            +L     ++ SLNKQ+ EL +  ++++ K  +M   +EN   E +I++L  E   LQ+ +
Sbjct: 1800 QLK---QQNQSLNKQIEELEQIRKKDLQKFQDM---IENGINENQILSLQKEKQELQSEL 1853

Query: 1548 RASSSKI----QKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDL 1591
            R S +K+    Q+ +   S   Q + +QL +  ++  LD     +L L
Sbjct: 1854 RVSKNKVDNLQQEQLILQSQLTQ-KTKQLIDIHDQIQLDEAKNVQLQL 1900



 Score =  120 bits (289), Expect = 3e-25
 Identities = 298/1601 (18%), Positives = 668/1601 (41%), Gaps = 164/1601 (10%)

Query: 68   SKRIKEHRKATAELLGRPFVPG---ISESLANTLKQKEILMEKIKQYKELSKRSS-TTIV 123
            +K +KE  +   E   +P++ G   +++ + N   + ++++ K KQY+EL + S   +  
Sbjct: 723  NKELKELEQFQGEQ-NQPYIQGQINLNDQINNL--EAQLILAK-KQYQELLETSQQNSSP 778

Query: 124  RXXXXXXXXXXXXXXXQLGDVTHLSNTIKEK----DNALSVLQVKMKIMETTILDLQEKI 179
                                + +LSN I+++    +  L+    ++++ E  IL+ +++ 
Sbjct: 779  NGLKEKILQQQALIHDYENQINNLSNKIEQEIPILEGQLATANQQIQVAENDILNQEKRY 838

Query: 180  NEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRL 239
            NE        N                     E  ++   ++Q+N   +E +  D +++L
Sbjct: 839  NE------LLNNKQYLQNPDTQIPSDDLKKLTEKNQELNLQLQQNNRKLEVQL-DIEEKL 891

Query: 240  LKDIESKDVRISSLEEANKL----LEAARFEISL---EHSKLAQELEQXXXXXXXXXXXX 292
             ++I  KD   +  ++  ++    ++  + +I+    +  +L QE+              
Sbjct: 892  KEEISEKDREYNLAQQIQQIQQDQIKDQQQKINKMIDKEQQLMQEIANLSSKINQQRDIN 951

Query: 293  XXLAKQSIEPSCEEKTEIEEKGS-LEIANMTELTKKI---ELLEHLNCQIRQTNKELENK 348
                KQ  + + ++  +I+E  S L+I  + E   K+    +L++  CQ+ Q  K    +
Sbjct: 952  VDNTKQDNQNNKDDIIQIQEDDSALKIKQLQEELNKVINENVLKNNECQVLQKLKPENEE 1011

Query: 349  LATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIA 408
            L    T+             ++  ++  +     K    Q + + L  +TD +     I+
Sbjct: 1012 LRAQQTQLYY---------QIVQLQNQIHNLESFKPSKQQDNDQQLTFETDPE-KTLAIS 1061

Query: 409  KLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHV 468
            +L+  IQ L   L  +E      +           G D          QQH+    L   
Sbjct: 1062 QLQQQIQQLRNQL--QEIQNQRAEDLQKFKEINENGAD----------QQHII--ELFQS 1107

Query: 469  GTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDE-IDAANKNMI 527
              N E   ++  +Q QL   L ++I  +    LI+K K   E  +  N+E      +N+ 
Sbjct: 1108 KQNLEQ--QLRNLQNQLDNALQEQI--LIQGQLIQKNKQFSEFCSNYNEEDFKKQLENLN 1163

Query: 528  KVKSNHKLKLKQMQKTIDNFSKVSDSN-------KEIVRLTEELHHLSQKVA----ELEE 576
            ++    + KL Q ++      +++  N       +++++   ++H   Q++     +L+ 
Sbjct: 1164 QIIQEQQEKLLQSKQQYQELLELTSQNLTPNGQKEKLLQQANQIHEQQQEIQLMHQQLDN 1223

Query: 577  EKGNLQLHLVDYDSG-RMIESDVYKKMIEMENLAETRLKAISLLE---SQKFDLVQELHI 632
            E   LQ  L +Y       +++++  M   +NL   R K     +   S K + +Q+ ++
Sbjct: 1224 EVPKLQGALAEYKQKYNDSQTEIHLLMERYQNLLNQRSKQDQSNDKSFSTKNNNLQDTNL 1283

Query: 633  LQQKYDEVEDKLADISQLQSD----QVCSEIKSVHLEEQIDALSASKKELALVIENLKLD 688
              QKYD+  D+  +IS  Q D     +  E +   + +Q +  S+  ++L   I +LK D
Sbjct: 1284 SAQKYDDKNDQ-TNISDFQDDINRKNILQEQEIALMHKQQEKFSSELEDLHKQI-SLK-D 1340

Query: 689  KEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQ 748
            +E L    K  E + E    +      +N        + S E+   L+  +  + Q  I 
Sbjct: 1341 QEILILKNKLAEGNTEFWKEEYTKLATQNKGSIKTQIQDSPEQY--LIVDLQQQSQKLIN 1398

Query: 749  TQFGIDAKIQERDL--YIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYL 806
                I+A+ QE DL  + + +E++ +K  S +    E+  + + +R  ++ + D L   L
Sbjct: 1399 QIAEIEAERQE-DLRKFQKILENDGTKDNSVVQLFSENQQLQQSKR-QMQNQIDDLLQQL 1456

Query: 807  QEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEEN---- 862
            ++++       IQ   L N++  L + ++++ KQL + + + ++LQ++ Q  L  N    
Sbjct: 1457 KDQKDLQDSKMIQN--LANQILELENQNQLLSKQLQQSKEQYQQLQEQLQANLTPNGLQE 1514

Query: 863  ---QNLQISLSDMQQHYNALVEKANRTDLAE-SESTKYQTQLRDLESNLKRITHEHQTLI 918
               QN QI +   Q+   AL  +  +TD+ E ++  +   Q +       R   E    +
Sbjct: 1515 KLLQNTQI-IHQQQEQILALQNQI-QTDIPEVTQQLQVADQNQKKALEEARNWKEKYLNL 1572

Query: 919  VQKKKEIEDLEIEFNTQIESAIRDKK----VLNEKYEKNIEYVTQLEAQLQEYKNNIENL 974
            ++ K+EI  ++I+ N   +  + + +     L + Y+K  E   Q +  + E K  I   
Sbjct: 1573 LEIKQEIPKIQIDDNIIKQMNLEESQDYIQTLVKNYQKANEQEQQAKILINEQKKLINQY 1632

Query: 975  NMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINN 1034
               +E  +  N ++I     K+       TE   ++I +L+   + + +E+I L  +   
Sbjct: 1633 ENQIEAQHSQNSDII-----KENAILNKLTETQNSQIERLSKSNQAQSQEMIDLKNQQRQ 1687

Query: 1035 AQV---SYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQ 1091
             Q     Y  +   Y   ++  +   E++  ++   + Q+    +   +  +L ++  DQ
Sbjct: 1688 EQYWKNEYQKLALKYGEDVSNKSPNQEDLINQIDE-NIQVESINELKNQNDLLQQQLIDQ 1746

Query: 1092 IKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFI 1151
            I+ELK TK+ F+  + + +  I        +D  NN              ++ Q + +  
Sbjct: 1747 IEELKLTKIKFQEQLLQAQRQI--------NDLLNN---QIPQPTQSQESIQFQNDPQKA 1795

Query: 1152 QERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTE-- 1209
             + S L++Q+  LN +++E   +I + +    +    + +N+ QI  L+ + ++L +E  
Sbjct: 1796 LQLSQLKQQNQSLNKQIEEL-EQIRKKDLQKFQDMIENGINENQILSLQKEKQELQSELR 1854

Query: 1210 -NDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQ---KTEHEL-RVQLSAF 1264
             + N +  + + +  + S + Q+  ++ ++  Q       + Q   + E++L + QL   
Sbjct: 1855 VSKNKVDNLQQEQLILQSQLTQKTKQLIDIHDQIQLDEAKNVQLQLQNENDLLKKQLHKI 1914

Query: 1265 ESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEI-- 1322
            + +Y++LL  +QS                 LQ K+  + +++ +L+E+   + +Q+E   
Sbjct: 1915 KEQYQELLQ-LQSENLTPNG----------LQEKILQQTQYIHDLEEQVQSLQHQVETQI 1963

Query: 1323 --LRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKS 1380
              L  EI + K+                   ++ + +  +   ++  L I E++ ++++ 
Sbjct: 1964 PQLSGEIVELKLKLKDAITDAQLWNNKYNEVIQIQQERSENQLQKLQLQIAEKDEKIEQQ 2023

Query: 1381 SXXXXXXXXXXXXRV--NDAEAKVLELTHQ---LELKDSEIYQKTHEYTITLTQRNDEFE 1435
                         ++  + A+AK+L+   Q   LE K        ++Y   L   N +  
Sbjct: 2024 KLKFDQLFQEQISQLSPSSAKAKLLKAFQQIIDLEEKLQAAEDLKNQYQSQLINVN-QSN 2082

Query: 1436 NVRQQLVEYEKRI---EDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEEL- 1491
             +  +L EY++++   E +   ++S+++  + ++ +        Q   ++E  K   +  
Sbjct: 2083 QILDELQEYKQKLEMQEKVNQIQDSQISFYKEQLSQQNQTPSNQQIMDQLENEKQKSQFW 2142

Query: 1492 NVKITESVSLNKQVAELNKALEEEVAKTNEM--QTALENQEI---EIVTLNDEITNLQNM 1546
              + TE +   +   +LN+ ++++  +  +   Q   +N +    EI  L  +   LQ +
Sbjct: 2143 KQQYTEMIKQKEPQGDLNEIIKQKEGEIVQQFKQPQDQNSQAFLKEIEDLKKQNIYLQQL 2202

Query: 1547 VRASSSKI---QKHVSFASDTKQGRDEQLDNTMNKELLDAV 1584
            +  + SK+   ++   F  +  Q +++Q     N+ L   V
Sbjct: 2203 IINTQSKLKTQEQKEQFQEEYSQDQEKQSLGLQNQALAKQV 2243



 Score =  117 bits (281), Expect = 3e-24
 Identities = 232/1202 (19%), Positives = 523/1202 (43%), Gaps = 104/1202 (8%)

Query: 380  SKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVI-QSLNKDLVDKEYVISEKDTXXXXX 438
            SK     SQ   +  NQ   ++  KNE  KL +   + ++    ++E +I++ D      
Sbjct: 1668 SKSNQAQSQEMIDLKNQQRQEQYWKNEYQKLALKYGEDVSNKSPNQEDLINQIDENIQVE 1727

Query: 439  XXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEI-KDVN 497
                      + Q QL  Q  +E   L    T  +   ++ + Q Q+   LN++I +   
Sbjct: 1728 SINELKNQNDLLQQQLIDQ--IEELKL----TKIKFQEQLLQAQRQINDLLNNQIPQPTQ 1781

Query: 498  VKDLIEKLKSAEE--QITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNF---SKVSD 552
             ++ I+     ++  Q++QL  +  + NK + +++   K  L++ Q  I+N    +++  
Sbjct: 1782 SQESIQFQNDPQKALQLSQLKQQNQSLNKQIEELEQIRKKDLQKFQDMIENGINENQILS 1841

Query: 553  SNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETR 612
              KE   L  EL     KV  L++E+  LQ  L    + ++I  D++ + I+++     +
Sbjct: 1842 LQKEKQELQSELRVSKNKVDNLQQEQLILQSQLTQ-KTKQLI--DIHDQ-IQLDEAKNVQ 1897

Query: 613  LKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALS 672
            L+    L+++   L ++LH ++++Y E       + QLQS+ +        + +Q   + 
Sbjct: 1898 LQ----LQNENDLLKKQLHKIKEQYQE-------LLQLQSENLTPNGLQEKILQQTQYIH 1946

Query: 673  ASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKI 732
              ++++  +   ++    QL G I +L+   +D +   Q +  +  ++    ++ S  ++
Sbjct: 1947 DLEEQVQSLQHQVETQIPQLSGEIVELKLKLKDAITDAQLWNNKYNEVIQIQQERSENQL 2006

Query: 733  SELLAKINHEEQSKIQTQFGIDAKIQER--DLYIENIESELSKYKSRICRLEESIAVMED 790
             +L  +I  +++   Q +   D   QE+   L   + +++L K   +I  LEE +   ED
Sbjct: 2007 QKLQLQIAEKDEKIEQQKLKFDQLFQEQISQLSPSSAKAKLLKAFQQIIDLEEKLQAAED 2066

Query: 791  RRYSLERK---ADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHE 847
             +   + +    +Q    L E Q+   +  +QE   VN++      D  +     ++  +
Sbjct: 2067 LKNQYQSQLINVNQSNQILDELQEYKQKLEMQEK--VNQI-----QDSQISFYKEQLSQQ 2119

Query: 848  NKELQKKNQILLEENQNLQISLSDMQQHYNALV-EKANRTDLAE----SESTKYQTQLRD 902
            N+     NQ ++++ +N +      +Q Y  ++ +K  + DL E     E    Q   + 
Sbjct: 2120 NQT--PSNQQIMDQLENEKQKSQFWKQQYTEMIKQKEPQGDLNEIIKQKEGEIVQQFKQP 2177

Query: 903  LESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEA 962
             + N +    E + L   KK+ I   ++  NTQ +   +++K   E++++  EY    E 
Sbjct: 2178 QDQNSQAFLKEIEDL---KKQNIYLQQLIINTQSKLKTQEQK---EQFQE--EYSQDQEK 2229

Query: 963  QLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKD 1022
            Q    +N  + L   VEEL ++N +++    Q  +  S D   Q I+E+ + N LL   +
Sbjct: 2230 QSLGLQN--QALAKQVEELKRINQDILQ---QMNKALSGDDKSQLISELLQKNTLLNLAN 2284

Query: 1023 EEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQ 1082
             +++ ++ + N  ++          S++      ++N++       KQ +   Q+  EL 
Sbjct: 2285 SKLL-IDLEANQKELFRQGQQQQQSSEM------IKNLDRSDMTDDKQRIADLQNQIEL- 2336

Query: 1083 ILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXL 1142
                +Q D  K+  +T L  + +   +   +    I+ +S   +  +            +
Sbjct: 2337 --AGQQIDFWKQKYQTVLN-DFSQQHSPTSLQKQLIDQVSQ-IHQQEEALFVLQQTTDKV 2392

Query: 1143 KVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSK 1202
            K+Q E +     + LQ +   +  ++ +   ++I  + +  +L+    + Q+Q+N+ +  
Sbjct: 2393 KLQNENQI----NSLQREIEIIKDQIDQLQKQLISEQNICQQLS-QQKIQQQQVNEKQIN 2447

Query: 1203 LEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELW-KQHLAQREADFQKTEH-ELRVQ 1260
              +   EN+  L +V E    + + + Q   E   L  +Q LAQ   + +  +   +  Q
Sbjct: 2448 FWKDKYENN--LKSVHENPEKVQTILKQAEKEAQNLIVEQDLAQINMNLELIDRLRMENQ 2505

Query: 1261 LSAFESKY--EQLLDSVQSSTQEETNKIVTME----QVTSLQNKLQDKEEHLRNLQEKYA 1314
             S  E K+  +++L+  Q   + + ++  T++    Q+T ++  LQ   ++    Q+KY 
Sbjct: 2506 KSQDEIKFYKKRVLELEQQQQKIQPSQYDTIQSRQYQITQMERDLQKAIQNQEFWQQKYN 2565

Query: 1315 DVINQ---IEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNIN 1371
            DV+ Q    EI +        ++                    E +   +   QS  ++ 
Sbjct: 2566 DVVQQNIDKEIGQQGDVQNSASYWRQKYDQAEQNRQELIQKIAEKEKQLEQNMQSFQSML 2625

Query: 1372 EENAQLKKSSXXXXXXXXXXXXRVNDAE-AKVLELTHQLELKD--SEIYQKTHEYTITLT 1428
            ++  + + +              +N++   + L+  H+ E +    E  ++  +  I+  
Sbjct: 2626 KDELKEELTKIRSQEKQKIPEQTLNESNLLQKLKEQHENEKQQLIQEFLRRIDQLLISNV 2685

Query: 1429 QRNDEFENVRQQLVEYEKRIEDLTYEKESELAIL---RLKMHENANHYETMQKESEIERV 1485
            Q+  E EN ++ +++YEK+ ++  YE + +L IL   +++  +   + E    E+ I  +
Sbjct: 2686 QKYPEGENWKELILKYEKQRQNELYELKQQLQILQRSQIQTQDIEFYAERRVYENTINEL 2745

Query: 1486 K--LIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNL 1543
            K  +  +   ++ +++   ++V +    LE++++  +  +  L NQ I+   LN+EI  L
Sbjct: 2746 KSRIQYDDQQELFDTIEYQRKVIQ---GLEDQISFISNQKQHL-NQHIQ--ELNEEIEML 2799

Query: 1544 QN 1545
            ++
Sbjct: 2800 RD 2801



 Score =  116 bits (279), Expect = 5e-24
 Identities = 242/1128 (21%), Positives = 479/1128 (42%), Gaps = 129/1128 (11%)

Query: 317  EIANMTELTKKIEL-LEHLNCQIRQTNKE---LENKLATMGTE--SKAVSSPSKKGSPLI 370
            EIA M +  +K    LE L+ QI   ++E   L+NKLA   TE   +  +  + +    I
Sbjct: 1314 EIALMHKQQEKFSSELEDLHKQISLKDQEILILKNKLAEGNTEFWKEEYTKLATQNKGSI 1373

Query: 371  SRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNE-IAKLEMVIQSLNKDLVDKEYVIS 429
              +   +    +     Q S + +NQ  + +  + E + K + ++++          + S
Sbjct: 1374 KTQIQDSPEQYLIVDLQQQSQKLINQIAEIEAERQEDLRKFQKILENDGTKDNSVVQLFS 1433

Query: 430  EKDTXXXXXXXXXXGKDTLIAQL--QLEHQQHMEGPSLIHVGTNTEDVNEIAKVQ-EQLK 486
            E               D L+ QL  Q + Q      +L +     E+ N++   Q +Q K
Sbjct: 1434 ENQQLQQSKRQMQNQIDDLLQQLKDQKDLQDSKMIQNLANQILELENQNQLLSKQLQQSK 1493

Query: 487  ---QELNDEIK-DVNVKDLIEKL-------KSAEEQI----TQLNDEIDAANKNMIKVKS 531
               Q+L ++++ ++    L EKL          +EQI     Q+  +I    + +     
Sbjct: 1494 EQYQQLQEQLQANLTPNGLQEKLLQNTQIIHQQQEQILALQNQIQTDIPEVTQQLQVADQ 1553

Query: 532  NHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSG 591
            N K  L++ +   + +  + +  +EI ++  + + + Q    LEE +  +Q  + +Y   
Sbjct: 1554 NQKKALEEARNWKEKYLNLLEIKQEIPKIQIDDNIIKQM--NLEESQDYIQTLVKNYQKA 1611

Query: 592  RMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQE---LHILQQKYDEVEDKLADIS 648
               E      + E + L       I    SQ  D+++E   L+ L +  +   ++L+  +
Sbjct: 1612 NEQEQQAKILINEQKKLINQYENQIEAQHSQNSDIIKENAILNKLTETQNSQIERLSKSN 1671

Query: 649  QLQSDQVCSEIKSVHLEEQIDALSASKKELALV--IENLKLDKEQLYGTIKDLENDKEDI 706
            Q QS ++  ++K+   +EQ       K  L     + N   ++E L   I   EN + + 
Sbjct: 1672 QAQSQEMI-DLKNQQRQEQYWKNEYQKLALKYGEDVSNKSPNQEDLINQID--ENIQVES 1728

Query: 707  MNKLQNYIQE-NMDLTDKLEKMSAEKIS--ELLAKINHEEQSKIQTQFGIDAKIQERDLY 763
            +N+L+N        L D++E++   KI   E L +   +    +  Q     + QE   +
Sbjct: 1729 INELKNQNDLLQQQLIDQIEELKLTKIKFQEQLLQAQRQINDLLNNQIPQPTQSQESIQF 1788

Query: 764  IENIES--ELSKYKSRICRLEESIAVMED-RRYSLERKAD---------QLGSYLQEKQK 811
              + +   +LS+ K +   L + I  +E  R+  L++  D         Q+ S  +EKQ+
Sbjct: 1789 QNDPQKALQLSQLKQQNQSLNKQIEELEQIRKKDLQKFQDMIENGINENQILSLQKEKQE 1848

Query: 812  AYSEYTIQE---DELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLE---ENQNL 865
              SE  + +   D L     +L        KQL++I H+  +L +   + L+   EN  L
Sbjct: 1849 LQSELRVSKNKVDNLQQEQLILQSQLTQKTKQLIDI-HDQIQLDEAKNVQLQLQNENDLL 1907

Query: 866  QISLSDMQQHYNALVE--KANRTDLAESESTKYQTQ-LRDLESNLKRITHEHQTLIVQKK 922
            +  L  +++ Y  L++    N T     E    QTQ + DLE  ++ + H+ +T I Q  
Sbjct: 1908 KKQLHKIKEQYQELLQLQSENLTPNGLQEKILQQTQYIHDLEEQVQSLQHQVETQIPQLS 1967

Query: 923  KEIEDLEIEFNTQIESAIRDKKVLNEKY--------EKNIEYVTQLEAQLQEYKNNIENL 974
             EI +L+++    ++ AI D ++ N KY        E++   + +L+ Q+ E    IE  
Sbjct: 1968 GEIVELKLK----LKDAITDAQLWNNKYNEVIQIQQERSENQLQKLQLQIAEKDEKIEQQ 2023

Query: 975  NMNVEELNKMNL-----------------ELID--KHVQKQQTQSPDYTEQYINEINKLN 1015
             +  ++L +  +                 ++ID  + +Q  +     Y  Q IN +N+ N
Sbjct: 2024 KLKFDQLFQEQISQLSPSSAKAKLLKAFQQIIDLEEKLQAAEDLKNQYQSQLIN-VNQSN 2082

Query: 1016 ALLKQKDE--EIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLD 1073
             +L +  E  + + + +K+N  Q S +S   +  S+  Q  +  + M++      K    
Sbjct: 2083 QILDELQEYKQKLEMQEKVNQIQDSQISFYKEQLSQQNQTPSNQQIMDQLENEKQKSQFW 2142

Query: 1074 SKQHNEELQILVREQD-DQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXX 1132
             +Q+ E ++    + D ++I + KE ++  +   P+ +     + ++ + D         
Sbjct: 2143 KQQYTEMIKQKEPQGDLNEIIKQKEGEIVQQFKQPQDQNS--QAFLKEIEDLKKQNIYLQ 2200

Query: 1133 XXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTG--HDV 1190
                     LK QE++E  QE     ++   L  + Q    ++ +L+ +N ++    +  
Sbjct: 2201 QLIINTQSKLKTQEQKEQFQEEYSQDQEKQSLGLQNQALAKQVEELKRINQDILQQMNKA 2260

Query: 1191 VNQEQINQLKSKLEQLNT----ENDNLL----STVAEL---------RSSISSAVDQRGF 1233
            ++ +  +QL S+L Q NT     N  LL    +   EL          S +   +D+   
Sbjct: 2261 LSGDDKSQLISELLQKNTLLNLANSKLLIDLEANQKELFRQGQQQQQSSEMIKNLDRSDM 2320

Query: 1234 -----EIAELWKQ-HLAQREADFQKTEHELRV----QLSAFESKYEQLLDSVQSSTQEET 1283
                  IA+L  Q  LA ++ DF K +++  +    Q  +  S  +QL+D V    Q+E 
Sbjct: 2321 TDDKQRIADLQNQIELAGQQIDFWKQKYQTVLNDFSQQHSPTSLQKQLIDQVSQIHQQE- 2379

Query: 1284 NKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEK 1331
              +  ++Q T  + KLQ+ E  + +LQ +   + +QI+ L+ ++  E+
Sbjct: 2380 EALFVLQQTTD-KVKLQN-ENQINSLQREIEIIKDQIDQLQKQLISEQ 2425



 Score = 89.8 bits (213), Expect = 5e-16
 Identities = 207/1121 (18%), Positives = 474/1121 (42%), Gaps = 102/1121 (9%)

Query: 230  AEWKDEKQRLLKDIES-KDVRISSLEEANKLLEAARFEIS-LEHSKLAQELEQXXXXXXX 287
            ++ K + Q L K IE  + +R   L++   ++E    E   L   K  QEL+        
Sbjct: 1799 SQLKQQNQSLNKQIEELEQIRKKDLQKFQDMIENGINENQILSLQKEKQELQSELR---- 1854

Query: 288  XXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELEN 347
                   ++K  ++   +E+  ++ + + +   + ++  +I+L E  N Q++  N   EN
Sbjct: 1855 -------VSKNKVDNLQQEQLILQSQLTQKTKQLIDIHDQIQLDEAKNVQLQLQN---EN 1904

Query: 348  KLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEI 407
             L       K +    ++   L+  +S   T + ++    Q +      D ++++   + 
Sbjct: 1905 DLL-----KKQLHKIKEQYQELLQLQSENLTPNGLQEKILQQTQYI--HDLEEQVQSLQ- 1956

Query: 408  AKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIH 467
             ++E  I  L+ ++V+ +  + +  T           K   + Q+Q E  ++      + 
Sbjct: 1957 HQVETQIPQLSGEIVELKLKLKDAITDAQLWN----NKYNEVIQIQQERSENQLQKLQLQ 2012

Query: 468  VGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAAN--KN 525
            +    E + +     +QL QE   ++   + K    KL  A +QI  L +++ AA   KN
Sbjct: 2013 IAEKDEKIEQQKLKFDQLFQEQISQLSPSSAK---AKLLKAFQQIIDLEEKLQAAEDLKN 2069

Query: 526  MIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTE-ELHHLSQKVAELEEEKGNLQLH 584
              + +  +  +  Q+   +  + +  +  +++ ++ + ++    +++++  +   N Q+ 
Sbjct: 2070 QYQSQLINVNQSNQILDELQEYKQKLEMQEKVNQIQDSQISFYKEQLSQQNQTPSNQQI- 2128

Query: 585  LVDYDSGRMIESDVYKKMI-EMENLAETRLKAISLLESQKFDLVQELHILQQKYD----- 638
             +D       +S  +K+   EM    E +     +++ ++ ++VQ+    Q +       
Sbjct: 2129 -MDQLENEKQKSQFWKQQYTEMIKQKEPQGDLNEIIKQKEGEIVQQFKQPQDQNSQAFLK 2187

Query: 639  EVEDKLADISQLQS--DQVCSEIKSVHLEEQI-DALSASKKELALVIENLKLDKEQLYGT 695
            E+ED       LQ       S++K+   +EQ  +  S  +++ +L ++N  L K+     
Sbjct: 2188 EIEDLKKQNIYLQQLIINTQSKLKTQEQKEQFQEEYSQDQEKQSLGLQNQALAKQ--VEE 2245

Query: 696  IKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDA 755
            +K +  D    MNK  +   ++  +++ L+K +   ++     I+ E   K   + G   
Sbjct: 2246 LKRINQDILQQMNKALSGDDKSQLISELLQKNTLLNLANSKLLIDLEANQKELFRQG--Q 2303

Query: 756  KIQERDLYIENIE-SELSKYKSRICRLEESIAVMEDRRYSLERKADQ-LGSYLQEKQKAY 813
            + Q+    I+N++ S+++  K RI  L+  I +   +    ++K    L  + Q+     
Sbjct: 2304 QQQQSSEMIKNLDRSDMTDDKQRIADLQNQIELAGQQIDFWKQKYQTVLNDFSQQHSPTS 2363

Query: 814  SEYTI--QEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSD 871
             +  +  Q  ++  +   L    +  +K  L+ E++   LQ++ +I+ ++   LQ  L  
Sbjct: 2364 LQKQLIDQVSQIHQQEEALFVLQQTTDKVKLQNENQINSLQREIEIIKDQIDQLQKQLIS 2423

Query: 872  MQQHYNALVE-KANRTDLAESE----STKYQTQLRDLESNLKRITHEHQTLIVQKKKEIE 926
             Q     L + K  +  + E +      KY+  L+ +  N +++    QT++ Q +KE +
Sbjct: 2424 EQNICQQLSQQKIQQQQVNEKQINFWKDKYENNLKSVHENPEKV----QTILKQAEKEAQ 2479

Query: 927  DLEIEFN-TQIESAIR--DK-KVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELN 982
            +L +E +  QI   +   D+ ++ N+K +  I++  +   +L++ +  I+    +  +  
Sbjct: 2480 NLIVEQDLAQINMNLELIDRLRMENQKSQDEIKFYKKRVLELEQQQQKIQPSQYDTIQSR 2539

Query: 983  KMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSM 1042
            +  +  +++ +QK   Q+ ++ +Q  N++ + N      D+EI       N+A  SY   
Sbjct: 2540 QYQITQMERDLQKA-IQNQEFWQQKYNDVVQQNI-----DKEIGQQGDVQNSA--SYWRQ 2591

Query: 1043 VSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTF 1102
              D            +N +E +Q+++++    +Q+ +  Q +++  D+  +EL + +   
Sbjct: 2592 KYDQAE---------QNRQELIQKIAEKEKQLEQNMQSFQSMLK--DELKEELTKIRSQE 2640

Query: 1103 EMNIPK---TEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQE 1159
            +  IP+    E  ++    E   ++   +               VQ+  E    + ++ +
Sbjct: 2641 KQKIPEQTLNESNLLQKLKEQHENEKQQLIQEFLRRIDQLLISNVQKYPEGENWKELILK 2700

Query: 1160 QSAKLNTELQECYTKI-----IQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLL 1214
               +   EL E   ++      Q++T + E      V +  IN+LKS+++    +   L 
Sbjct: 2701 YEKQRQNELYELKQQLQILQRSQIQTQDIEFYAERRVYENTINELKSRIQY--DDQQELF 2758

Query: 1215 STVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDS 1274
             T+   R  I    DQ  F   +  KQHL Q   +  +    LR  L     KY+   D+
Sbjct: 2759 DTIEYQRKVIQGLEDQISFISNQ--KQHLNQHIQELNEEIEMLRDNL----QKYQLQSDN 2812

Query: 1275 VQSSTQEETNKIVTMEQVTSLQNKLQDKE-EHLRNLQEKYA 1314
             +    E    I  M++  + +   Q    + +R  Q KY+
Sbjct: 2813 RKKQRLEVLEAISEMKRERTRERDSQKSPFQSMRPSQNKYS 2853



 Score = 87.4 bits (207), Expect = 3e-15
 Identities = 191/989 (19%), Positives = 414/989 (41%), Gaps = 86/989 (8%)

Query: 160  VLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTK--QQ 217
            V+Q++ +  E  +  LQ +I EKD+ IE +                      +  K  QQ
Sbjct: 1994 VIQIQQERSENQLQKLQLQIAEKDEKIEQQKLKFDQLFQEQISQLSPSSAKAKLLKAFQQ 2053

Query: 218  MTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQE 277
            +  ++E   A E + K++ Q  L ++   +  +  L+E  + LE       ++ S+++  
Sbjct: 2054 IIDLEEKLQAAE-DLKNQYQSQLINVNQSNQILDELQEYKQKLEMQEKVNQIQDSQISFY 2112

Query: 278  LEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQ 337
             EQ               + Q I    E +   ++K        TE+ K+ E    LN  
Sbjct: 2113 KEQLSQQNQTP-------SNQQIMDQLENE---KQKSQFWKQQYTEMIKQKEPQGDLNEI 2162

Query: 338  IRQTNKELENKL---ATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKS-PWSQLSSET 393
            I+Q   E+  +        +++        K   +  ++   NT SK+K+    +   E 
Sbjct: 2163 IKQKEGEIVQQFKQPQDQNSQAFLKEIEDLKKQNIYLQQLIINTQSKLKTQEQKEQFQEE 2222

Query: 394  LNQDTDKK---INKNEIAKLEMVIQSLNKDLVDK-EYVISEKDTXXXXXXXXXXGKDTLI 449
             +QD +K+   +    +AK    ++ +N+D++ +    +S  D            K+TL 
Sbjct: 2223 YSQDQEKQSLGLQNQALAKQVEELKRINQDILQQMNKALSGDDKSQLISELLQ--KNTL- 2279

Query: 450  AQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAE 509
              L L + +      LI +  N +++      Q Q +Q+ ++ IK+++  D+ +     +
Sbjct: 2280 --LNLANSK-----LLIDLEANQKELFR----QGQQQQQSSEMIKNLDRSDMTDD----K 2324

Query: 510  EQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQ 569
            ++I  L ++I+ A + +   K  ++  L    +        +   K+++    ++H   +
Sbjct: 2325 QRIADLQNQIELAGQQIDFWKQKYQTVLNDFSQQ----HSPTSLQKQLIDQVSQIHQQEE 2380

Query: 570  KVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMI-EMENLAETRLKAISLLESQKFDLVQ 628
             +  L++    ++L   +  +    E ++ K  I +++    +       L  QK    Q
Sbjct: 2381 ALFVLQQTTDKVKLQNENQINSLQREIEIIKDQIDQLQKQLISEQNICQQLSQQKIQ-QQ 2439

Query: 629  ELHILQQKY--DEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELAL---VIE 683
            +++  Q  +  D+ E+ L  + +   ++V + +K    E Q   +     ++ +   +I+
Sbjct: 2440 QVNEKQINFWKDKYENNLKSVHE-NPEKVQTILKQAEKEAQNLIVEQDLAQINMNLELID 2498

Query: 684  NLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEE 743
             L+++ ++    IK  +    ++  + Q       D     +    +   +L   I ++E
Sbjct: 2499 RLRMENQKSQDEIKFYKKRVLELEQQQQKIQPSQYDTIQSRQYQITQMERDLQKAIQNQE 2558

Query: 744  --QSKIQ--TQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKA 799
              Q K     Q  ID +I ++     +      KY       +E I  + ++   LE+  
Sbjct: 2559 FWQQKYNDVVQQNIDKEIGQQGDVQNSASYWRQKYDQAEQNRQELIQKIAEKEKQLEQNM 2618

Query: 800  DQLGSYLQEKQKAYSEYT-IQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQIL 858
                S L+++ K   E T I+  E        ++   +++K  L+ +HEN++ Q   + L
Sbjct: 2619 QSFQSMLKDELK--EELTKIRSQEKQKIPEQTLNESNLLQK--LKEQHENEKQQLIQEFL 2674

Query: 859  LEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEH-QTL 917
               +Q L   +S++Q++     E  N  +L      + Q +L +L+  L+ +     QT 
Sbjct: 2675 RRIDQLL---ISNVQKY----PEGENWKELILKYEKQRQNELYELKQQLQILQRSQIQTQ 2727

Query: 918  IVQKKKEIEDLEIEFNTQIESAIR--DKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLN 975
             ++   E    E   N +++S I+  D++ L +  E   + +  LE Q+    N  ++LN
Sbjct: 2728 DIEFYAERRVYENTIN-ELKSRIQYDDQQELFDTIEYQRKVIQGLEDQISFISNQKQHLN 2786

Query: 976  MNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALN---QKI 1032
             +++ELN+  +E++  ++QK Q QS +  +Q +  +  ++ + +++  E  +     Q +
Sbjct: 2787 QHIQELNE-EIEMLRDNLQKYQLQSDNRKKQRLEVLEAISEMKRERTRERDSQKSPFQSM 2845

Query: 1033 NNAQVSYMS--MVSDY--ESKLAQFTTKLENMEEEMQRV---SKQLLDSKQHNEELQILV 1085
              +Q  Y       DY   S + Q  +  +     +QR+   S Q + S+Q N E+   +
Sbjct: 2846 RPSQNKYSQDRYPRDYLRPSNIPQQFSSFKEHNSPIQRIPYPSVQFISSQQENREIPQKL 2905

Query: 1086 REQDDQIKELKETKLTFEMNIPKTEGMII 1114
            +E    ++E+K    T   NI K E  ++
Sbjct: 2906 QE----LEEVKNKYQTALNNILKLETQVV 2930



 Score = 55.6 bits (128), Expect = 1e-05
 Identities = 92/484 (19%), Positives = 216/484 (44%), Gaps = 56/484 (11%)

Query: 447  TLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIA----KVQEQLK------QELNDEIKDV 496
            T++ Q + E Q  +    L  +  N E ++ +     K Q+++K       EL  + + +
Sbjct: 2469 TILKQAEKEAQNLIVEQDLAQINMNLELIDRLRMENQKSQDEIKFYKKRVLELEQQQQKI 2528

Query: 497  NVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQ-MQKTIDNFSKVSDS-- 553
                  + ++S + QITQ+  ++  A +N    +  +   ++Q + K I     V +S  
Sbjct: 2529 QPSQY-DTIQSRQYQITQMERDLQKAIQNQEFWQQKYNDVVQQNIDKEIGQQGDVQNSAS 2587

Query: 554  --NKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAET 611
               ++  +  +    L QK+AE E++   L+ ++  + S  M++ ++ +++ ++ +  + 
Sbjct: 2588 YWRQKYDQAEQNRQELIQKIAEKEKQ---LEQNMQSFQS--MLKDELKEELTKIRSQEKQ 2642

Query: 612  RLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQI--- 668
            ++   +L ES     ++E H   +K   +++ L  I QL    V    +  + +E I   
Sbjct: 2643 KIPEQTLNESNLLQKLKEQHE-NEKQQLIQEFLRRIDQLLISNVQKYPEGENWKELILKY 2701

Query: 669  -----DALSASKKELALVIEN-LKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTD 722
                 + L   K++L ++  + ++    + Y   +  EN   ++ +++Q   Q+ +  T 
Sbjct: 2702 EKQRQNELYELKQQLQILQRSQIQTQDIEFYAERRVYENTINELKSRIQYDDQQELFDTI 2761

Query: 723  KLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYK-----SR 777
            + ++   + + + ++ I++++Q        ++  IQE +  IE +   L KY+      +
Sbjct: 2762 EYQRKVIQGLEDQISFISNQKQH-------LNQHIQELNEEIEMLRDNLQKYQLQSDNRK 2814

Query: 778  ICRLEESIAVMEDRRYSLERKADQLGSY--LQEKQKAYSEYTIQEDEL-----VNRLAVL 830
              RLE   A+ E +R     +  Q   +  ++  Q  YS+     D L       + +  
Sbjct: 2815 KQRLEVLEAISEMKRERTRERDSQKSPFQSMRPSQNKYSQDRYPRDYLRPSNIPQQFSSF 2874

Query: 831  MDHDRVVEK------QLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKAN 884
             +H+  +++      Q +  + EN+E+ +K Q L E     Q +L+++ +    +VEK  
Sbjct: 2875 KEHNSPIQRIPYPSVQFISSQQENREIPQKLQELEEVKNKYQTALNNILKLETQVVEKLQ 2934

Query: 885  RTDL 888
            + D+
Sbjct: 2935 QDDI 2938



 Score = 48.4 bits (110), Expect = 0.002
 Identities = 51/177 (28%), Positives = 89/177 (50%), Gaps = 25/177 (14%)

Query: 815 EYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQ 874
           E  +   E+    +VL+D    +EK+ + ++++N++LQ++ QILL E QN +  ++D+QQ
Sbjct: 46  EKVLMSFEIQRLNSVLLD----IEKKRIAMKNQNQKLQEREQILLLEIQNQKQQINDIQQ 101

Query: 875 HYNALVEKANRTDLAESEST--KYQTQLRD--LESNLKRITHEHQTLIVQKKKEIEDLEI 930
                 EK +R  L + + T  K + Q+RD  +   +K++  E   L+ QK   +    +
Sbjct: 102 K-----EKNSRDQLNQLQRTFSKQENQIRDQLMSDEIKKL-QEENILLEQKLSYL----L 151

Query: 931 EFNTQIESAIRDKKVLNEKYEKNIE-YVTQLEAQLQEYKNNIENLNMNVEELNKMNL 986
           E N Q    I++  VL +K    ++     L   LQ      ENL  N+ +  K NL
Sbjct: 152 EVNQQ---QIKNDNVLFQKSGGQLKGKENVLPYSLQ---TGFENLQNNIMQFRKGNL 202


>UniRef50_A0BCM0 Cluster: Chromosome undetermined scaffold_10, whole
            genome shotgun sequence; n=3; Paramecium tetraurelia|Rep:
            Chromosome undetermined scaffold_10, whole genome shotgun
            sequence - Paramecium tetraurelia
          Length = 1328

 Score =  131 bits (316), Expect = 2e-28
 Identities = 209/1113 (18%), Positives = 459/1113 (41%), Gaps = 68/1113 (6%)

Query: 466  IHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKN 525
            I + T    ++ +    + L+QEL  + + +N++D  +K+K  ++ I QL +E++     
Sbjct: 156  IQLRTENASIDSLQGTIKTLQQELASKQERINLRD--DKIKQQDDIIDQLQNELNHLQGL 213

Query: 526  MIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHL 585
             ++V++   LK +Q+   +   +   +     +R    L     +V  LE EK  L+   
Sbjct: 214  KLEVEN---LK-QQVHFKVQELTTCKEKLAAALREVGALRLYKGEVQVLESEKQLLRDE- 268

Query: 586  VDYDSGRMIESDVYKKMIEMENLA------ETRLKAISLLESQKFDLVQELHILQQKYDE 639
            VD+     +  ++ K+++E+E L+      E +LK I  LE +   L    ++L     E
Sbjct: 269  VDH-----LRGEIQKRLLEVEELSFIKASQEAQLKQIPFLEDEISTL---RNLLADAISE 320

Query: 640  VEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDL 699
                     QLQ++ +  + K    E ++D      + L  + ++L    +++       
Sbjct: 321  KGILQTQFGQLQNENLALDNKYHTQEGELDEFKLDNQRLLQINDHLNEQLQKVRNERNQF 380

Query: 700  ENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQE 759
            E D + +   L +  Q   D  +K  ++  E I EL  ++N   Q  +Q +  + AK ++
Sbjct: 381  ERDADQLDKTLHDVQQLLADAEEKNAQLEKE-IKELKDELNKLRQQNLQQELDLQAKDRQ 439

Query: 760  RDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQ 819
             +      E  L++ +  I R E+ I   +D+    E+    L  +  E  K       Q
Sbjct: 440  HEQQRVQYEGYLNELQLEIQRKEQLIKNWKDKYLQSEQLVSDL-QFTAELLKQEQIRARQ 498

Query: 820  EDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNAL 879
             +  + RL     H    + + +  + E  +L+K+ Q L  EN +    +  ++Q    L
Sbjct: 499  LELEIERLKQRQLHQPPPQIEHIVDQDEINQLRKQIQELHRENFDQYQQIQKLKQQIEQL 558

Query: 880  VEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDL-EIEFNTQ-IE 937
                N  ++ E+E   Y  ++  L++ L     E++    Q + ++ DL +  FN + +E
Sbjct: 559  ---NNHINILENEKHLYIQEIDRLKTQLNMKVEENE----QMRAKMNDLNQTIFNLKHLE 611

Query: 938  SAIRD-KKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMN-LELIDKH--- 992
            S + + ++ +N   + + + + QL  + +EY++          E N++N L+L +     
Sbjct: 612  SRVPELEQTINLLRQHSQDLIQQLNVKTKEYEDLYGRYFDKSLEANQVNQLQLSNNKLDI 671

Query: 993  VQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMV---SDYESK 1049
            V++++ Q+ +  +  +N++   N  L+ +++E      K    +V Y+  +   S  +  
Sbjct: 672  VRQEEVQNRENVKTDLNKVGVDNDRLR-REKEYYESKYKYLLLEVEYLQRLKAESLQQDP 730

Query: 1050 LAQF--------TTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLT 1101
            L +            + N+E + Q +  QL   +  NE+    + + + Q+++L+   + 
Sbjct: 731  LLELRGGNQDDVNEDIANLERQQQVLQDQLAKLQSQNEQKDKEIDDLNAQLRQLQAENIQ 790

Query: 1102 FEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQS 1161
               N  + +  ++ + I  +   ++N                   + +  Q      +Q 
Sbjct: 791  DLYNKLQQQYSLLQTQITNLQQSSSNSSAEKDNYINELESHINDLQNQLQQLDQQRSKQI 850

Query: 1162 AKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELR 1221
              L  +LQ+   +  +L    T+LT        ++N ++  +EQLN   +  +   A   
Sbjct: 851  GDLQAQLQKLLDENNKLRQQLTDLTNKFNSQVSEMNSMQKVIEQLNGFQNEFIKYKALYE 910

Query: 1222 SSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQE 1281
                   D +  ++ +L KQ   Q  A+       L  +++  +++ EQL   +Q    E
Sbjct: 911  RECLVTADLKD-QLGQLDKQ-ARQLAAE----RDNLLDRIAKLQAEIEQLGKQIQVKNDE 964

Query: 1282 ETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXX 1341
               +  T+  +     +L+  E   + L++       ++  LR ++ D ++A        
Sbjct: 965  NAAQSKTVSTLEGQVAQLKPLEAENQRLKQLIDQQTKELGDLRQKLADLQLAADDANKQK 1024

Query: 1342 XXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAK 1401
                        + N  ++Q++ +     NE NA LK S+              N     
Sbjct: 1025 TQFQQLY----NSVNGEFEQLKNKFAAKDNEINA-LKASNTKQESIVKQVKVIDNTNPND 1079

Query: 1402 VLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAI 1461
            +  L  Q+  +  E      E      Q + E + V++   E  K ++     K+ EL  
Sbjct: 1080 LKTLQDQIAQRSKE----NEEIKKKFNQMDVELQKVKKDNTEISK-LQQAIQAKDKELDD 1134

Query: 1462 LRLKMH---ENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAK 1518
            L+ K+    +++++ E ++KE E +   L  +LN       +    + +LN+ + +   +
Sbjct: 1135 LKKKLDKFSQDSSNLEKLKKELEAKVNSLNSDLNTSKKNFDNQQNDIKKLNQQINDLQNE 1194

Query: 1519 TNEMQTALENQEIEIVTLNDEITNLQNMVRASS 1551
                Q  + NQ  ++ T N++  ++   +R+ +
Sbjct: 1195 IKRQQNIISNQTSDLQTWNNKYASVVKDLRSDN 1227



 Score =  109 bits (261), Expect = 8e-22
 Identities = 207/1068 (19%), Positives = 446/1068 (41%), Gaps = 91/1068 (8%)

Query: 556  EIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKA 615
            ++ +L +E   L+ ++  L EE G LQ  + +      I   +   +  +++  + +L+ 
Sbjct: 29   DVQQLNDENARLNDEIKRLMEELGKLQSQVSELREQTTIIEQLRSDLHNVQHQLDLKLQQ 88

Query: 616  ISLLESQKFDLVQELHILQQKYDEV---EDKLADISQLQSDQVCSEIKSVHLEE---QID 669
            I  L         EL  LQ         E+KL  + Q + D++ S +K    E    ++ 
Sbjct: 89   IDDLNHDVQTRDAELFKLQGGSSVTIVTENKLLQM-QSEIDRLQSLLKQREAELDGWRLK 147

Query: 670  ALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSA 729
              S  K  + L  EN  +D   L GTIK L+   +++ +K     QE ++L D   K   
Sbjct: 148  YSSLEKVNIQLRTENASIDS--LQGTIKTLQ---QELASK-----QERINLRDDKIKQQD 197

Query: 730  EKISELLAKINHEEQSKIQTQF---GIDAKIQERDLYIENIESELSK------YKSRICR 780
            + I +L  ++NH +  K++ +     +  K+QE     E + + L +      YK  +  
Sbjct: 198  DIIDQLQNELNHLQGLKLEVENLKQQVHFKVQELTTCKEKLAAALREVGALRLYKGEVQV 257

Query: 781  LEESIAVMEDR----RYSLERKADQLG--SYLQEKQKAY-SEYTIQEDE---LVNRLAVL 830
            LE    ++ D     R  ++++  ++   S+++  Q+A   +    EDE   L N LA  
Sbjct: 258  LESEKQLLRDEVDHLRGEIQKRLLEVEELSFIKASQEAQLKQIPFLEDEISTLRNLLADA 317

Query: 831  MDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQIS---LSDMQQHYNALVEKA-NRT 886
            +    +++ Q  ++++EN  L  K      E    ++    L  +  H N  ++K  N  
Sbjct: 318  ISEKGILQTQFGQLQNENLALDNKYHTQEGELDEFKLDNQRLLQINDHLNEQLQKVRNER 377

Query: 887  DLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVL 946
            +  E ++ +    L D++  L     ++     Q +KEI++L+ E N   +  ++ +  L
Sbjct: 378  NQFERDADQLDKTLHDVQQLLADAEEKN----AQLEKEIKELKDELNKLRQQNLQQELDL 433

Query: 947  NEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSP-DYTE 1005
              K         Q E Q  +Y+  +  L + ++   ++     DK++Q +Q  S   +T 
Sbjct: 434  QAKDR-------QHEQQRVQYEGYLNELQLEIQRKEQLIKNWKDKYLQSEQLVSDLQFTA 486

Query: 1006 QYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEE-- 1063
            + + +  ++ A  +Q + EI  L Q+  +     +  + D + ++ Q   +++ +  E  
Sbjct: 487  ELLKQ-EQIRA--RQLELEIERLKQRQLHQPPPQIEHIVD-QDEINQLRKQIQELHRENF 542

Query: 1064 --MQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPM 1121
               Q++ K     +Q N  + IL  E+   I+E+   K    M + + E M   + +  +
Sbjct: 543  DQYQQIQKLKQQIEQLNNHINILENEKHLYIQEIDRLKTQLNMKVEENEQM--RAKMNDL 600

Query: 1122 SDDANNVDXXXXXXXXXXXXLKV--QEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLE 1179
            +    N+             + +  Q  ++ IQ+ +V  ++   L     +   +  Q+ 
Sbjct: 601  NQTIFNLKHLESRVPELEQTINLLRQHSQDLIQQLNVKTKEYEDLYGRYFDKSLEANQVN 660

Query: 1180 TLNTELTGHDVVNQEQI---NQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQ----RG 1232
             L       D+V QE++     +K+ L ++  +ND L        S     + +    + 
Sbjct: 661  QLQLSNNKLDIVRQEEVQNRENVKTDLNKVGVDNDRLRREKEYYESKYKYLLLEVEYLQR 720

Query: 1233 FEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTME-Q 1291
             +   L +  L +     Q   +E    L   +   +  L  +QS  +++  +I  +  Q
Sbjct: 721  LKAESLQQDPLLELRGGNQDDVNEDIANLERQQQVLQDQLAKLQSQNEQKDKEIDDLNAQ 780

Query: 1292 VTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXD 1351
            +  LQ   ++ ++    LQ++Y+ +  QI  L+    +                      
Sbjct: 781  LRQLQ--AENIQDLYNKLQQQYSLLQTQITNLQQSSSNSSAEKDNYINELESHINDLQNQ 838

Query: 1352 L-RTENQSYKQM--QEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQ 1408
            L + + Q  KQ+   +  +  + +EN +L++               +N  + KV+E  + 
Sbjct: 839  LQQLDQQRSKQIGDLQAQLQKLLDENNKLRQQLTDLTNKFNSQVSEMNSMQ-KVIEQLNG 897

Query: 1409 LE---LKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAIL--- 1462
             +   +K   +Y++    T  L  +  + +   +QL      + D   + ++E+  L   
Sbjct: 898  FQNEFIKYKALYERECLVTADLKDQLGQLDKQARQLAAERDNLLDRIAKLQAEIEQLGKQ 957

Query: 1463 -RLKMHENANHYETMQK-ESEIERVKLIEELNVKITESV-SLNKQVAELNKALEE-EVAK 1518
             ++K  ENA   +T+   E ++ ++K +E  N ++ + +    K++ +L + L + ++A 
Sbjct: 958  IQVKNDENAAQSKTVSTLEGQVAQLKPLEAENQRLKQLIDQQTKELGDLRQKLADLQLAA 1017

Query: 1519 TNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQ 1566
             +  +   + Q++   ++N E   L+N   A  ++I  +   AS+TKQ
Sbjct: 1018 DDANKQKTQFQQL-YNSVNGEFEQLKNKFAAKDNEI--NALKASNTKQ 1062



 Score = 37.5 bits (83), Expect = 3.0
 Identities = 61/325 (18%), Positives = 135/325 (41%), Gaps = 27/325 (8%)

Query: 1245 QREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEE 1304
            +R  D++      + +    E+  +QL D   +   +E  ++  ME++  LQ+++ +  E
Sbjct: 7    ERAIDYETLIQAEQARNEELENDVQQLNDE-NARLNDEIKRL--MEELGKLQSQVSELRE 63

Query: 1305 HLRNLQEKYADVIN---QIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQ 1361
                +++  +D+ N   Q+++   +I+D                      + TEN+  + 
Sbjct: 64   QTTIIEQLRSDLHNVQHQLDLKLQQIDDLNHDVQTRDAELFKLQGGSSVTIVTENKLLQM 123

Query: 1362 MQE----QSILNINE---ENAQLKKSS-XXXXXXXXXXXXRVNDAEAKVLELTHQLELKD 1413
              E    QS+L   E   +  +LK SS              ++  +  +  L  +L  K 
Sbjct: 124  QSEIDRLQSLLKQREAELDGWRLKYSSLEKVNIQLRTENASIDSLQGTIKTLQQELASKQ 183

Query: 1414 SEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHY 1473
              I  +  +    + Q++D  + ++ +L      ++ L  E E+    +  K+ E     
Sbjct: 184  ERINLRDDK----IKQQDDIIDQLQNEL----NHLQGLKLEVENLKQQVHFKVQELTTCK 235

Query: 1474 ETMQKE-SEIERVKLIE-ELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEI 1531
            E +     E+  ++L + E+ V  +E   L  +V  L   +++ + +  E+     +QE 
Sbjct: 236  EKLAAALREVGALRLYKGEVQVLESEKQLLRDEVDHLRGEIQKRLLEVEELSFIKASQEA 295

Query: 1532 ---EIVTLNDEITNLQNMVRASSSK 1553
               +I  L DEI+ L+N++  + S+
Sbjct: 296  QLKQIPFLEDEISTLRNLLADAISE 320


>UniRef50_Q22AS4 Cluster: Putative uncharacterized protein; n=1;
            Tetrahymena thermophila SB210|Rep: Putative
            uncharacterized protein - Tetrahymena thermophila SB210
          Length = 1441

 Score =  130 bits (315), Expect = 2e-28
 Identities = 220/1153 (19%), Positives = 508/1153 (44%), Gaps = 104/1153 (9%)

Query: 472  TEDVNEIAKVQEQLK-QELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVK 530
            T+DV  I ++Q +L+ QE  + + +  +K +  ++++ E +IT+L  +ID  + N+ K+ 
Sbjct: 212  TQDVR-IEELQRELRGQEEKNVLLNEKIKHMQIQIQNRESEITRLQSKIDIGSLNVDKLS 270

Query: 531  SNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLS---QKVAELEEEKGNLQLHLVD 587
             +++++ +Q++K      ++    KE  ++  EL +L    +++  ++EE  NL   +  
Sbjct: 271  KDYQIE-QQVEKVERLNHQIDFLTKENHQMDTELKNLKSDLKRIQMIKEENRNLSDKV-- 327

Query: 588  YDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFD-LVQELHILQQKYDEVEDKLAD 646
            YD  + +ES   +++IE  +    +++ +   + QK +  ++     ++++D     L D
Sbjct: 328  YDLNQSLESA--RRIIESHDAKRKQIEDLYKNQLQKLEEKLKNNDASKEEFDNQYKDLED 385

Query: 647  -ISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKED 705
             I +LQ +    + ++   ++ ++A  + K+  +  +E+++ +KEQ              
Sbjct: 386  EIKRLQQENEQLKQEASRADQVVNAYQSDKRVFSQAVESVRAEKEQ-------------- 431

Query: 706  IMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIE 765
             ++K++ Y++E  +   +L+    EK       I H + S++Q +  +    Q+R L  E
Sbjct: 432  ALSKMEKYVKELEEKQVQLQDYEDEK------AILHSKISQLQREIDLTNANQDR-LSSE 484

Query: 766  N--IESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDEL 823
            N  +  E+ + K+ I  LE+    + D+    + + +++      KQK + +  I+  + 
Sbjct: 485  NRLLNDEILRLKANIRSLEQDNLDLNDKYKDAKLEGERI-----LKQKDFLQDQIERAK- 538

Query: 824  VNRLAVLMDHD-RVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEK 882
             +      D D + + ++ LE  +EN  LQK+N IL ++  NL+     M Q   +L+ +
Sbjct: 539  TDTYKFKSDVDTQSIARERLEKLYEN--LQKENSILKKDIGNLE----QMNQQSKSLILE 592

Query: 883  ANRTDLAESESTKYQTQLRDLESNLKRITHEHQ---TLIVQKKKEIEDLEI------EFN 933
                  AE +  +  TQ+R L+  +K +  +++    +I QK KEI  +E         N
Sbjct: 593  ------AEEKQREQFTQIRILQDQVKELERQNKLSNDVIDQKSKEIRQIESARAETEREN 646

Query: 934  TQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNV----EELNKMNLEL- 988
             Q+ +  R    + +K ++ +E +T LE +  +     + L  ++    E + K+  +L 
Sbjct: 647  LQLTAIKRKYDDIVDKQKRQLEQITDLEDKRLKVIREADQLKFDIMDKEESIKKLQDQLR 706

Query: 989  IDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYES 1048
            I++  + +  Q      Q  + IN+     K+K+ E   +  ++   +      + + E+
Sbjct: 707  IERDERVRLAQELQSISQETDSINQTIQKSKEKETEYSYIALELEKTRERERKQIIEIEA 766

Query: 1049 KLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQI---KELKETKLTFEMN 1105
                  T++  ME+ + + ++Q+ +     EE    ++E   ++   K  KE   T  + 
Sbjct: 767  ----LQTEVRKMEQLISQGTRQVENLNNQKEEYLKEIKELRKEMLNTKSDKENGFTKSIQ 822

Query: 1106 IPK---TEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSA 1162
            + +   T+ +++    + +S +   V              +  E+ + I E     +Q  
Sbjct: 823  LQEKINTQELLVQDLKDSLSKEERKVKNLENEIKILTN--ENTEQRQRIYEIETNNKQLK 880

Query: 1163 KLNTELQECYTKIIQ-LETLNTELT---GHDVVNQEQINQLKSKLEQLNTE---NDNLLS 1215
             +   L+    ++++ L+  N+E     G  +  Q++I  L  +L ++N E     + + 
Sbjct: 881  TIAEGLERAKEELLERLQNRNSERVEEEGEKIKLQKEIQSLGKQLNEVNQELKQAQDSIV 940

Query: 1216 TVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSV 1275
            T+ + R  I   +D++  E  ++ KQ L Q E D +K   + R +LS+   +  Q +  +
Sbjct: 941  TIDQERDEIQEQLDKKILENEKI-KQVLEQYENDLEKL-RDKRNELSSKSDQSVQRVIQL 998

Query: 1276 QSSTQEETNKI-VTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAF 1334
            +++ +++  KI   + +V + +  L  K++ L++L      V  + + L  E+   K+A 
Sbjct: 999  EATIKDQNKKIQQLLLEVDNCKYTLTVKDKELQDLANDLNVVTRENQNLTGEL--VKIAG 1056

Query: 1335 XXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSIL----NINEENAQLKKSSXXXXXXXXX 1390
                              + +     +M++  +L     +  +N +L++ S         
Sbjct: 1057 ERDDIRHQLNNVMIEEKKQKQGLRAVEMEKSDLLTQYKQVCIDNERLERQSQDLIIENQN 1116

Query: 1391 XXXRVNDAEAKVLELTHQL---ELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKR 1447
               +  D E ++  L   L   E K  ++          +T  N + E   Q + +  + 
Sbjct: 1117 LFRKAQDLEKELALLQGHLGHHEGKQGQMINDLKNMERQITFLNQKLEQADQHIRDIIQE 1176

Query: 1448 IEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQV-A 1506
             E++  + +S + + +  +  N +  +      E E+++L+E LN+   E  +   ++  
Sbjct: 1177 KENIHRQYDSMMRVSQ-GLEGNRDEMQRQLMTLENEKIQLVENLNMLKRECEAKASELDY 1235

Query: 1507 ELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQ 1566
              N+  + E     E Q A   Q +E+ ++  E   +   +     +      +  D + 
Sbjct: 1236 HRNRVSQLEEILLRERQ-AQHRQSLEVQSIIQERDQISRQLDEMKQQNLNLQGYLQDNE- 1293

Query: 1567 GRDEQLDNTMNKE 1579
             R+  L N+  K+
Sbjct: 1294 -RNNSLYNSAQKD 1305



 Score =  110 bits (264), Expect = 4e-22
 Identities = 173/937 (18%), Positives = 387/937 (41%), Gaps = 71/937 (7%)

Query: 668  IDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKM 727
            ++ L     +++ + +N+K    +    I   E   E +  +    I+EN DL   + K+
Sbjct: 31   VERLLNENLKISEMYQNVKKQNNEALKNIAKAEQSLEPLKKENAKLIKENNDLHYAMIKV 90

Query: 728  SAEKI---SELLAKINHEEQSKIQTQFGIDAK-IQERDLYIENI--ESELSKYKSRIC-- 779
              +     +      N  E  K   +F +D K  + R +  EN+  +++L  + S++   
Sbjct: 91   KEDAELANNRWKTTYNSLEGEKNDLKFLVDQKEARIRKVEDENLALKTKLDTFMSKVYIP 150

Query: 780  ----RLEE------SIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAV 829
                 LE       +  +      SL +K +Q    L +    ++EY    +E +   A 
Sbjct: 151  STQGGLENLPPSYINANISAPTNISLSKKGNQFD--LNKPLNEFNEYQNNREEEMRNWA- 207

Query: 830  LMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLA 889
              D  R  + ++ E++ E +  ++KN +L E+ +++QI + + +     L  K +   L 
Sbjct: 208  --DQIRTQDVRIEELQRELRGQEEKNVLLNEKIKHMQIQIQNRESEITRLQSKIDIGSLN 265

Query: 890  ESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEK 949
              + +K   Q+      ++R+ H+   L     KE   ++ E    ++S ++  +++ E+
Sbjct: 266  VDKLSK-DYQIEQQVEKVERLNHQIDFL----TKENHQMDTELK-NLKSDLKRIQMIKEE 319

Query: 950  YEKNIEYVTQLEAQLQEYKNNIEN---LNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQ 1006
                 + V  L   L+  +  IE+       +E+L K  L+ +++ ++       ++  Q
Sbjct: 320  NRNLSDKVYDLNQSLESARRIIESHDAKRKQIEDLYKNQLQKLEEKLKNNDASKEEFDNQ 379

Query: 1007 Y---INEINKLNALLKQKDEEIIALNQKINNAQVS---YMSMVSDYESKLAQFTTKLENM 1060
            Y    +EI +L    +Q  +E    +Q +N  Q     +   V    ++  Q  +K+E  
Sbjct: 380  YKDLEDEIKRLQQENEQLKQEASRADQVVNAYQSDKRVFSQAVESVRAEKEQALSKMEKY 439

Query: 1061 EEEMQRVSKQLLDSKQHNEEL--QILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTI 1118
             +E++    QL D +     L  +I   +++  +    + +L+ E  +   E + + + I
Sbjct: 440  VKELEEKQVQLQDYEDEKAILHSKISQLQREIDLTNANQDRLSSENRLLNDEILRLKANI 499

Query: 1119 EPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQ---ERSVLQEQSAKLNTELQECYTKI 1175
              +  D  N+D             ++ ++++F+Q   ER+       K + + Q    + 
Sbjct: 500  RSLEQD--NLDLNDKYKDAKLEGERILKQKDFLQDQIERAKTDTYKFKSDVDTQSIARER 557

Query: 1176 IQ--LETLNTE--LTGHDVVNQEQIN-QLKSKLEQLNTENDNLLSTVAELRSSISSAVDQ 1230
            ++   E L  E  +   D+ N EQ+N Q KS + +   +     + +  L+  +     Q
Sbjct: 558  LEKLYENLQKENSILKKDIGNLEQMNQQSKSLILEAEEKQREQFTQIRILQDQVKELERQ 617

Query: 1231 RGF--EIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLD----SVQSSTQEETN 1284
                 ++ +   + + Q E+   +TE E  +QL+A + KY+ ++D     ++  T  E  
Sbjct: 618  NKLSNDVIDQKSKEIRQIESARAETERE-NLQLTAIKRKYDDIVDKQKRQLEQITDLEDK 676

Query: 1285 KIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIE--DEKVAFXXXXXXXX 1342
            ++  + +   L+  + DKEE ++ LQ++     ++   L  E++   ++           
Sbjct: 677  RLKVIREADQLKFDIMDKEESIKKLQDQLRIERDERVRLAQELQSISQETDSINQTIQKS 736

Query: 1343 XXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKV 1402
                     +  E +  ++ + + I+ I     +++K                N  E  +
Sbjct: 737  KEKETEYSYIALELEKTRERERKQIIEIEALQTEVRKMEQLISQGTRQVENLNNQKEEYL 796

Query: 1403 LELTHQLELKDSEIYQKTHEYT--ITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELA 1460
             E+    +   +    K + +T  I L ++ +  E + Q L +   + E      E+E+ 
Sbjct: 797  KEIKELRKEMLNTKSDKENGFTKSIQLQEKINTQELLVQDLKDSLSKEERKVKNLENEIK 856

Query: 1461 IL-------RLKMHE---NANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNK 1510
            IL       R +++E   N    +T+ +  E  + +L+E L  + +E V    +  +L K
Sbjct: 857  ILTNENTEQRQRIYEIETNNKQLKTIAEGLERAKEELLERLQNRNSERVEEEGEKIKLQK 916

Query: 1511 ALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMV 1547
             ++    + NE+   L+  +  IVT++ E   +Q  +
Sbjct: 917  EIQSLGKQLNEVNQELKQAQDSIVTIDQERDEIQEQL 953



 Score = 92.3 bits (219), Expect = 1e-16
 Identities = 149/789 (18%), Positives = 333/789 (42%), Gaps = 79/789 (10%)

Query: 839  KQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQT 898
            K + + E   + L+K+N  L++EN +L         HY A+++     +LA +       
Sbjct: 57   KNIAKAEQSLEPLKKENAKLIKENNDL---------HY-AMIKVKEDAELANNRWKTTYN 106

Query: 899  QLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYV- 957
             L   +++LK +  + +  I    +++ED  +   T++++ +   KV     +  +E + 
Sbjct: 107  SLEGEKNDLKFLVDQKEARI----RKVEDENLALKTKLDTFM--SKVYIPSTQGGLENLP 160

Query: 958  -TQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINE---INK 1013
             + + A +    N   +   N  +LNK  L   +++   ++ +  ++ +Q   +   I +
Sbjct: 161  PSYINANISAPTNISLSKKGNQFDLNK-PLNEFNEYQNNREEEMRNWADQIRTQDVRIEE 219

Query: 1014 LNALLKQKDEEIIALNQKINNAQVSYM---SMVSDYESKLAQFTTKLENMEEEMQRVSKQ 1070
            L   L+ ++E+ + LN+KI + Q+      S ++  +SK+   +  ++ + ++ Q + +Q
Sbjct: 220  LQRELRGQEEKNVLLNEKIKHMQIQIQNRESEITRLQSKIDIGSLNVDKLSKDYQ-IEQQ 278

Query: 1071 LLDSKQHNEELQILVREQDDQIKELKETKLTFE-MNIPKTEGMIISSTIEPMSDDANNVD 1129
            +   ++ N ++  L +E      ELK  K   + + + K E   +S  +  +     N  
Sbjct: 279  VEKVERLNHQIDFLTKENHQMDTELKNLKSDLKRIQMIKEENRNLSDKVYDL-----NQS 333

Query: 1130 XXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHD 1189
                         K ++ E+  + +    E+  K N   +E +    Q + L  E+    
Sbjct: 334  LESARRIIESHDAKRKQIEDLYKNQLQKLEEKLKNNDASKEEFDN--QYKDLEDEIKRLQ 391

Query: 1190 VVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREAD 1249
              N EQ+ Q  S+ +Q+     +     ++   S+ +  +Q      E + + L +++  
Sbjct: 392  QEN-EQLKQEASRADQVVNAYQSDKRVFSQAVESVRAEKEQ-ALSKMEKYVKELEEKQVQ 449

Query: 1250 FQKTEHELRVQLSAFESKYEQL-LDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRN 1308
             Q  E E  +  S       ++ L +         N+++  +++  L+  ++  E+   +
Sbjct: 450  LQDYEDEKAILHSKISQLQREIDLTNANQDRLSSENRLLN-DEILRLKANIRSLEQDNLD 508

Query: 1309 LQEKYAD-------VINQIEILRSEIEDEKV-AFXXXXXXXXXXXXXXXXDLRTEN-QSY 1359
            L +KY D       ++ Q + L+ +IE  K   +                +   EN Q  
Sbjct: 509  LNDKYKDAKLEGERILKQKDFLQDQIERAKTDTYKFKSDVDTQSIARERLEKLYENLQKE 568

Query: 1360 KQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQK 1419
              + ++ I N+ + N Q K               ++   + +V EL  Q +L +  I QK
Sbjct: 569  NSILKKDIGNLEQMNQQSKSLILEAEEKQREQFTQIRILQDQVKELERQNKLSNDVIDQK 628

Query: 1420 THEYTITLTQRNDEFENVRQQLVEYEKRIEDLT------YEKESELAILRLKMHENANH- 1472
            + E    +     E E    QL   +++ +D+        E+ ++L   RLK+   A+  
Sbjct: 629  SKEIR-QIESARAETERENLQLTAIKRKYDDIVDKQKRQLEQITDLEDKRLKVIREADQL 687

Query: 1473 -YETMQKESEIERVKLIEELNVKITESVSLNKQVAELNK---ALEEEVAKTNEMQT---- 1524
             ++ M KE  I+  KL ++L ++  E V L +++  +++   ++ + + K+ E +T    
Sbjct: 688  KFDIMDKEESIK--KLQDQLRIERDERVRLAQELQSISQETDSINQTIQKSKEKETEYSY 745

Query: 1525 -ALE---------NQEIEIVTLNDEITNLQNMVRASSSKIQ----KHVSFASDTKQGRDE 1570
             ALE          Q IEI  L  E+  ++ ++   + +++    +   +  + K+ R E
Sbjct: 746  IALELEKTRERERKQIIEIEALQTEVRKMEQLISQGTRQVENLNNQKEEYLKEIKELRKE 805

Query: 1571 QLDNTMNKE 1579
             L+   +KE
Sbjct: 806  MLNTKSDKE 814



 Score = 79.0 bits (186), Expect = 1e-12
 Identities = 175/968 (18%), Positives = 423/968 (43%), Gaps = 95/968 (9%)

Query: 153  EKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXE 212
            EK+ ALS ++  +K +E   + LQ+  +EK  I+ +K                       
Sbjct: 428  EKEQALSKMEKYVKELEEKQVQLQDYEDEK-AILHSKISQLQREIDLTNANQDRLSSENR 486

Query: 213  DTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARF-EISLEH 271
                ++ +++ N  ++E +  D     L D + KD ++    E  ++L+   F +  +E 
Sbjct: 487  LLNDEILRLKANIRSLEQDNLD-----LND-KYKDAKL----EGERILKQKDFLQDQIER 536

Query: 272  SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELL 331
            +K                     +A++ +E   E    ++++ S+   ++  L +  +  
Sbjct: 537  AK-------TDTYKFKSDVDTQSIARERLEKLYE---NLQKENSILKKDIGNLEQMNQQS 586

Query: 332  EHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSS 391
            + L  +  +  +E   ++  +  + K +   +K  + +I +KS      +++S  ++   
Sbjct: 587  KSLILEAEEKQREQFTQIRILQDQVKELERQNKLSNDVIDQKS--KEIRQIESARAETER 644

Query: 392  ETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEY-VISEKDTXXXXXXXXXXGKDTLIA 450
            E L     K+   + + K +  ++ +  DL DK   VI E D               L  
Sbjct: 645  ENLQLTAIKRKYDDIVDKQKRQLEQIT-DLEDKRLKVIREADQLKFDIMDKEESIKKLQD 703

Query: 451  QLQLEHQQHME-GPSLIHVGTNTEDVNEIAKVQEQLKQELN------DEIKDVNVKDL-- 501
            QL++E  + +     L  +   T+ +N+  +  ++ + E +      ++ ++   K +  
Sbjct: 704  QLRIERDERVRLAQELQSISQETDSINQTIQKSKEKETEYSYIALELEKTRERERKQIIE 763

Query: 502  IEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSN-KEIVRL 560
            IE L++   ++ QL  +     +N+   K  +  ++K+++K + N     ++   + ++L
Sbjct: 764  IEALQTEVRKMEQLISQGTRQVENLNNQKEEYLKEIKELRKEMLNTKSDKENGFTKSIQL 823

Query: 561  TEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLE 620
             E+++     V +L++     +  +      + +E+++  K++  EN  E R +   +  
Sbjct: 824  QEKINTQELLVQDLKDSLSKEERKV------KNLENEI--KILTNEN-TEQRQRIYEIET 874

Query: 621  SQKFDLVQELHILQQKYDEVEDKLAD-ISQLQSDQVCSEIKSVHLEEQIDALSASKKELA 679
            + K     +L  + +  +  +++L + +    S++V  E + + L+++I +L    K+L 
Sbjct: 875  NNK-----QLKTIAEGLERAKEELLERLQNRNSERVEEEGEKIKLQKEIQSLG---KQLN 926

Query: 680  LVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMS------AEKIS 733
             V + LK    Q   +I  ++ ++++I  +L   I EN  +   LE+         +K +
Sbjct: 927  EVNQELK----QAQDSIVTIDQERDEIQEQLDKKILENEKIKQVLEQYENDLEKLRDKRN 982

Query: 734  ELLAKINHEEQSKIQTQFGI---DAKIQERDLYIENIESELSKYKSRICRLEESIAVMED 790
            EL +K +   Q  IQ +  I   + KIQ+  L ++N +  L+     +  L   + V+  
Sbjct: 983  ELSSKSDQSVQRVIQLEATIKDQNKKIQQLLLEVDNCKYTLTVKDKELQDLANDLNVVTR 1042

Query: 791  RRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRL-AVLMDHDRVVEKQLLEIEHENK 849
               +L  +  ++     + +   +   I+E +    L AV M+   ++  Q  ++  +N+
Sbjct: 1043 ENQNLTGELVKIAGERDDIRHQLNNVMIEEKKQKQGLRAVEMEKSDLL-TQYKQVCIDNE 1101

Query: 850  ELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKR 909
             L++++Q L+ ENQNL     D+++    L     +  L   E  + Q  + DL++  ++
Sbjct: 1102 RLERQSQDLIIENQNLFRKAQDLEKELALL-----QGHLGHHEGKQGQ-MINDLKNMERQ 1155

Query: 910  ITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKN 969
            IT  +Q L  Q  + I D+           I++K+ ++ +Y+  +     LE    E + 
Sbjct: 1156 ITFLNQKL-EQADQHIRDI-----------IQEKENIHRQYDSMMRVSQGLEGNRDEMQR 1203

Query: 970  NIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALN 1029
             +  L     +L + NL ++ +  + + ++  DY   + N +++L  +L ++ +     +
Sbjct: 1204 QLMTLENEKIQLVE-NLNMLKRECEAKASEL-DY---HRNRVSQLEEILLRERQAQHRQS 1258

Query: 1030 QKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEEL-QILVREQ 1088
             ++ +  +     +S    ++ Q    L+   ++ +R +  L +S Q ++++  +L ++ 
Sbjct: 1259 LEVQSI-IQERDQISRQLDEMKQQNLNLQGYLQDNER-NNSLYNSAQKDQKIVPVLEKKI 1316

Query: 1089 DDQIKELK 1096
            DD+ + +K
Sbjct: 1317 DDKNQLIK 1324



 Score = 66.5 bits (155), Expect = 6e-09
 Identities = 162/786 (20%), Positives = 330/786 (41%), Gaps = 84/786 (10%)

Query: 215  KQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLE-EANKLLEAARFEISLEHSK 273
            + +  ++ +   ++  E     Q + K  E K+   S +  E  K  E  R +I +E   
Sbjct: 709  RDERVRLAQELQSISQETDSINQTIQKSKE-KETEYSYIALELEKTRERERKQI-IEIEA 766

Query: 274  LAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEH 333
            L  E+ +              L  Q  E   E K   +E  + +       TK I+L E 
Sbjct: 767  LQTEVRKMEQLISQGTRQVENLNNQKEEYLKEIKELRKEMLNTKSDKENGFTKSIQLQEK 826

Query: 334  LNCQ------IRQTNKELENKLATMGTESKAVSSPSKKGSPLI-----SRKSGRNTASKM 382
            +N Q      ++ +  + E K+  +  E K +++ + +    I     + K  +  A  +
Sbjct: 827  INTQELLVQDLKDSLSKEERKVKNLENEIKILTNENTEQRQRIYEIETNNKQLKTIAEGL 886

Query: 383  KSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXX 442
            +    +L     N+++++   + E  KL+  IQSL K L +   V  E            
Sbjct: 887  ERAKEELLERLQNRNSERVEEEGEKIKLQKEIQSLGKQLNE---VNQELKQAQDSIVTID 943

Query: 443  XGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLI 502
              +D +  QL    ++ +E   +  V    E  N++ K++++ + EL+ +  D +V+ +I
Sbjct: 944  QERDEIQEQLD---KKILENEKIKQVLEQYE--NDLEKLRDK-RNELSSK-SDQSVQRVI 996

Query: 503  E---KLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVR 559
            +    +K   ++I QL  E+D   K  + VK       K++Q   ++ + V+  N+    
Sbjct: 997  QLEATIKDQNKKIQQLLLEVDNC-KYTLTVKD------KELQDLANDLNVVTRENQ---N 1046

Query: 560  LTEELHHLSQKVAELEEEKGNLQLHLVDYDSG-RMIESDVYKKMIEMENLAETRLKAISL 618
            LT EL  ++ +  ++  +  N+ +       G R +E +    + + + +     +    
Sbjct: 1047 LTGELVKIAGERDDIRHQLNNVMIEEKKQKQGLRAVEMEKSDLLTQYKQVCIDNER---- 1102

Query: 619  LESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKEL 678
            LE Q  DL+ E   L +K  ++E +LA    LQ      E K     + I+ L   ++++
Sbjct: 1103 LERQSQDLIIENQNLFRKAQDLEKELA---LLQGHLGHHEGKQ---GQMINDLKNMERQI 1156

Query: 679  ALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAK 738
              +  N KL  EQ    I+D+  +KE+I  +  + ++ +  L    ++M  + ++     
Sbjct: 1157 TFL--NQKL--EQADQHIRDIIQEKENIHRQYDSMMRVSQGLEGNRDEMQRQLMT----- 1207

Query: 739  INHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERK 798
                E  KIQ    ++   +E     E   SEL  +++R+ +LEE   ++   R +  R+
Sbjct: 1208 ---LENEKIQLVENLNMLKRE----CEAKASELDYHRNRVSQLEE---ILLRERQAQHRQ 1257

Query: 799  ADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDR------VVEKQLLEIEHENKELQ 852
            + ++ S +QE+ +   +    + + +N    L D++R        +K    +    K++ 
Sbjct: 1258 SLEVQSIIQERDQISRQLDEMKQQNLNLQGYLQDNERNNSLYNSAQKDQKIVPVLEKKID 1317

Query: 853  KKNQILLE-ENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRD-----LESN 906
             KNQ++   E++ +Q+   + +   N ++ +  + DL +       +Q+ D      E N
Sbjct: 1318 DKNQLIKTLESEQIQLRQENSKLKLNMVLYQKEKEDLEKRLYNLKDSQMSDTIKSSYEKN 1377

Query: 907  LKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNI--EYVTQLEAQL 964
             ++  ++ Q    Q  + I+    EF   +  A      LN+   KN+  EY   L    
Sbjct: 1378 PRQQDNDQQN--QQGWERIQAERREFQKSLNEASMRSYALNQNV-KNLKKEYDQVLPPSS 1434

Query: 965  QEYKNN 970
             + KNN
Sbjct: 1435 TKSKNN 1440



 Score = 54.0 bits (124), Expect = 3e-05
 Identities = 141/670 (21%), Positives = 269/670 (40%), Gaps = 53/670 (7%)

Query: 878  ALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIE 937
            A+VE+    +L  SE   YQ   +     LK I    Q+L   KK+  +   I+ N  + 
Sbjct: 29   AMVERLLNENLKISEM--YQNVKKQNNEALKNIAKAEQSLEPLKKENAK--LIKENNDLH 84

Query: 938  SAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQ 997
             A+   KV  +    N  + T   + L+  KN+++ L   V++      ++ D+++  + 
Sbjct: 85   YAMI--KVKEDAELANNRWKTTYNS-LEGEKNDLKFL---VDQKEARIRKVEDENLALKT 138

Query: 998  TQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKL 1057
                  ++ YI        L       I A      N  +S      D    L +F    
Sbjct: 139  KLDTFMSKVYIPSTQ--GGLENLPPSYINANISAPTNISLSKKGNQFDLNKPLNEFNEYQ 196

Query: 1058 ENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISST 1117
             N EEEM+  + Q+       EELQ  +R Q+++   L E     ++ I   E  I  + 
Sbjct: 197  NNREEEMRNWADQIRTQDVRIEELQRELRGQEEKNVLLNEKIKHMQIQIQNRESEI--TR 254

Query: 1118 IEPMSDDAN-NVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKII 1176
            ++   D  + NVD             +V++ E    +   L +++ +++TEL+   + + 
Sbjct: 255  LQSKIDIGSLNVDKLSKDYQIEQ---QVEKVERLNHQIDFLTKENHQMDTELKNLKSDLK 311

Query: 1177 QLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIA 1236
            +++ +  E         +++  L   LE        ++ +    R  I      +  ++ 
Sbjct: 312  RIQMIKEENRN----LSDKVYDLNQSLESAR----RIIESHDAKRKQIEDLYKNQLQKLE 363

Query: 1237 ELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTS-- 1294
            E  K + A +E +F     +L  ++   + + EQL     S   +  N   + ++V S  
Sbjct: 364  EKLKNNDASKE-EFDNQYKDLEDEIKRLQQENEQLKQEA-SRADQVVNAYQSDKRVFSQA 421

Query: 1295 LQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRT 1354
            +++   +KE+ L  + EKY   + + ++   + EDEK                   DL  
Sbjct: 422  VESVRAEKEQALSKM-EKYVKELEEKQVQLQDYEDEKAIL-----HSKISQLQREIDLTN 475

Query: 1355 ENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDS 1414
             NQ   ++  ++ L +N+E  +LK +             +  DA+   LE    L+ KD 
Sbjct: 476  ANQD--RLSSENRL-LNDEILRLKANIRSLEQDNLDLNDKYKDAK---LEGERILKQKDF 529

Query: 1415 EIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYE 1474
               Q     T T   ++D    V  Q +  E R+E L    + E +IL+    ++  + E
Sbjct: 530  LQDQIERAKTDTYKFKSD----VDTQSIARE-RLEKLYENLQKENSILK----KDIGNLE 580

Query: 1475 TMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIV 1534
             M ++S+   ++  E+   + T+   L  QV EL +  + +++     Q + E ++IE  
Sbjct: 581  QMNQQSKSLILEAEEKQREQFTQIRILQDQVKELER--QNKLSNDVIDQKSKEIRQIESA 638

Query: 1535 TLNDEITNLQ 1544
                E  NLQ
Sbjct: 639  RAETERENLQ 648


>UniRef50_A2F8N8 Cluster: Putative uncharacterized protein; n=2;
            Eukaryota|Rep: Putative uncharacterized protein -
            Trichomonas vaginalis G3
          Length = 1996

 Score =  130 bits (315), Expect = 2e-28
 Identities = 244/1298 (18%), Positives = 527/1298 (40%), Gaps = 90/1298 (6%)

Query: 212  EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271
            E T+++ ++ +E     E +++ E+++  K+  +++ +I   E  N  LE  + E  +  
Sbjct: 736  EATEEKYSEREELMKPTEPDFQQEEKQ--KEEVNEEKQIDRKE--NDFLEETKEE-QIHE 790

Query: 272  SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELL 331
             K++ +++                A++S   S E  +E EE+  ++       +++    
Sbjct: 791  VKVSDDIKDDFKEEQKEIEHESNNAEESTNKSKEVVSETEEESKVQTKERENPSEEETKE 850

Query: 332  EHLNCQIRQTNK-ELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLS 390
            E    + ++  K E   ++     E +       K       +      +K + P+   +
Sbjct: 851  EPFEDEYKEETKDENTEEIKEEPFEDETKEENKDKNKEETKEEEPFEDETKEEEPFEDEN 910

Query: 391  SETLNQDT---DKKINKNEIAK---LEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXG 444
             E   ++T   +K  NK E  +    E   +  NKD   +E     KD            
Sbjct: 911  KEETKEETKEENKDENKEETKEEEPFEDETKEENKDENKEETKEETKDKSKEETKEETKD 970

Query: 445  KDTLIAQLQLE-HQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIE 503
            +         E  +++ +     +   N E+  E  K + + ++   DE K+    +  E
Sbjct: 971  ETKEEEPFDGETKEENKDENKEENKDENKEETKEENKEETKEEEPFEDETKEETKDETKE 1030

Query: 504  KLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEE 563
            + K   ++     DE     K   K ++  + K +  ++T +      ++ +E    T+E
Sbjct: 1031 ETKDETKEEEPFEDESKEETKEENKDENKEETKEETKEETKEEEPFEDENKEETKEETKE 1090

Query: 564  LHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQK 623
                  +    EE K        + +  +    D Y++  + EN  + +       E + 
Sbjct: 1091 DEPFEDETK--EENKEEEPFEDENKEETKEDNKDDYEEETKHENNVQEQ-------EDEP 1141

Query: 624  FDLVQELHILQQKYDEV-EDKLADISQLQSDQVCSEIKSV-HLEEQIDALSASKKELALV 681
             +    +  + ++++EV +D+  +  +   +++  E+K       Q D     +      
Sbjct: 1142 TNKANPIASVDEEFEEVFKDEDREFEKHSQEELNREVKEEREFIPQKDETKDQESNHEDF 1201

Query: 682  IENLKLDKEQLYGTIKDLENDK-EDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKIN 740
             E +K +++    TIK+ E  K E + N     I+E  D+ +K E+++ +K+ E+  + N
Sbjct: 1202 EEEIKEEQKIDEDTIKEEEEQKTEKVQNDFDEEIKEE-DIKEKHEEVTKDKV-EMNEEQN 1259

Query: 741  HEEQSKIQTQFGIDAKIQERDL-------YIENIESELSKYKSRICRLEESIAVMEDRRY 793
             EE+ + + +  I+  I E+++        I++ E E+  Y  +  R E+S  V E+R  
Sbjct: 1260 DEEKQQQEVESTIEEDITEQNVEPKKEEQTIQDFEEEVQNYDDK--REEQSEKVHEEREI 1317

Query: 794  SL-------ERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEH 846
             L       E K ++L    ++K++ + E   +E+         +  +   E+QL E E 
Sbjct: 1318 VLNIEQPQEEEKKEELHEEEEKKEELHEEEEKKEELHEEEKKEELHEEEKKEEQLHEEEE 1377

Query: 847  ENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESN 906
            E KE     ++  EE + ++  L + ++      E+     L E E  K + QL + E  
Sbjct: 1378 ETKE-----ELHEEEEEKIE-KLHEEEKKEELHEEEKKEEQLHEEEEEKKEEQLHE-EEE 1430

Query: 907  LKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLN-EKYEKNIEYVTQLEAQLQ 965
             K   HE      +KK+E+ + E +     E     K+ L+ E+ E+  E + + E + +
Sbjct: 1431 KKEELHEE-----EKKEELHEEEKKEELHEEEEEEKKEELHEEEEEEKKEELHEEEEKKE 1485

Query: 966  EYKNNIENLNMNVEELNKMNLELIDKHVQKQQT-QSPDYTEQYINEINKLNALLKQKDEE 1024
            E +  IE L+   EE  K  L   ++  +K++  +  +  E+   +I KL+   ++K E+
Sbjct: 1486 EEEEKIEKLHEEEEEEKKEELHEEEEEEKKEELHEEEEKKEEEEEKIEKLHEEEEKKKEQ 1545

Query: 1025 IIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQIL 1084
                     N +++Y   + + E   ++   K    EE+ +    +  D K+  EE + +
Sbjct: 1546 --------TNEEINYNPAIKEVEGPESEEENKYRKDEEDFEDEKNEESDYKKQKEESESV 1597

Query: 1085 VREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEP--------MSDDANNVDXXXXXXX 1136
             +E ++   E +      E N PK E   ++ T           ++DD    +       
Sbjct: 1598 AKELEETSTENRNNNQE-ETNQPKLENSSLNITEVKEETEEKVNITDDFETENQNEDRET 1656

Query: 1137 XXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQI 1196
                   + +E E I+E+    E+  +   E QE   + I+      E    D   +E+ 
Sbjct: 1657 DAETEKAIHQENEQIREKDFHDEKQIENEEEKQEILKEPIEERNFQQENDFKD-NEEEEK 1715

Query: 1197 NQLKSKLEQLNTENDNL--LSTVAELRSSISSAVDQRGFEI--AELWKQHLAQREADFQK 1252
             + + K+E+L+ + + +  L    E +  +    +++  ++   E  K+ L + E   + 
Sbjct: 1716 KEEEEKIEKLHEKEEKIEKLHEEEEKKEELHEEEEKKEEQLHEEEEKKEELHEEEKKEEL 1775

Query: 1253 TEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEK 1312
             E E + +L   E K EQL +  +   +E+ ++    E+    + K   KEE L   +EK
Sbjct: 1776 HEEEKKEELHEEEKKEEQLHE--EEKKEEQLHEEEKKEEQLHEEEK---KEEQLHE-EEK 1829

Query: 1313 YADVINQIEILRSEI-EDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNIN 1371
              + +++ E    ++ E+EK                   + + E Q +++ +++    ++
Sbjct: 1830 KEEQLHEEEKKEEQLHEEEKKEELHEEEEKKEEQLHEEEEEKKEEQLHEEEEKKE--ELH 1887

Query: 1372 EENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEI-YQKTHEYTITLTQR 1430
            EE  + ++                 + E    +  H L   D EI  ++  E  +   + 
Sbjct: 1888 EEEKKEEQPHEEVVVVEEKMEQPQEEEEDNEADGIHSLSDFDEEISTEEKVEIKVQEKEE 1947

Query: 1431 NDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHE 1468
            N++F+   ++++E EK  +++  E+ +E    R K  E
Sbjct: 1948 NNDFDAEEEKILE-EKLEKEIIEEENNETEDDRPKKSE 1984



 Score =  101 bits (241), Expect = 2e-19
 Identities = 262/1426 (18%), Positives = 575/1426 (40%), Gaps = 101/1426 (7%)

Query: 173  LDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMT-KMQENFIAMEAE 231
            +D  +K +EK+Q  +++  +                   E    +++ K QE     + +
Sbjct: 627  IDSAQKESEKEQAKQSEETSNLESEFESEKHKESSKEETESDNDKLSDKKQEKDKETDDD 686

Query: 232  WKDE--KQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXX 289
            +++E  K ++ +  E K   I S  E +K  +    E    ++++  + E+         
Sbjct: 687  FEEEGKKDQITQSEEEKLNEIIS-SEGDKEKDFHFIEEKKPNNEIQDDFEEATEEKYSER 745

Query: 290  XXXXXLAKQSIEPSCEEKTEIEEKGSLEIA--NMTELTKKIELLE-HLNCQIRQTNKELE 346
                   +   +   ++K E+ E+  ++    +  E TK+ ++ E  ++  I+   KE +
Sbjct: 746  EELMKPTEPDFQQEEKQKEEVNEEKQIDRKENDFLEETKEEQIHEVKVSDDIKDDFKEEQ 805

Query: 347  NKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNE 406
             ++      ++  ++ SK+       +S   T  + ++P  + + E   +D  K+  K+E
Sbjct: 806  KEIEHESNNAEESTNKSKEVVSETEEESKVQTKER-ENPSEEETKEEPFEDEYKEETKDE 864

Query: 407  IAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLI 466
                    + + ++  + E     KD            +D    +   E +   E     
Sbjct: 865  NT------EEIKEEPFEDETKEENKDKNKEETKEEEPFEDETKEEEPFEDENKEETKEET 918

Query: 467  HVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIE--KLKSAEEQITQLNDEIDAANK 524
                N ++  E  K +E  + E  +E KD N ++  E  K KS EE   +  DE      
Sbjct: 919  KE-ENKDENKEETKEEEPFEDETKEENKDENKEETKEETKDKSKEETKEETKDETKEEEP 977

Query: 525  NMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLH 584
               + K  +K + K+  K  +N  +  + NKE  +  EE      K    +E K   +  
Sbjct: 978  FDGETKEENKDENKEENKD-ENKEETKEENKEETK-EEEPFEDETKEETKDETKEETKDE 1035

Query: 585  LVDYDSGRMIESDVYKKMIEMENLAETRLKAIS-LLESQKF-DLVQELHILQQKYDE-VE 641
              + +       +  K+  + EN  ET+ +      E + F D  +E    + K DE  E
Sbjct: 1036 TKEEEPFEDESKEETKEENKDENKEETKEETKEETKEEEPFEDENKEETKEETKEDEPFE 1095

Query: 642  DKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIE--NLKLDKEQLYGTI-KD 698
            D+  + ++ + +    E K    E+  D      K    V E  +   +K     ++ ++
Sbjct: 1096 DETKEENK-EEEPFEDENKEETKEDNKDDYEEETKHENNVQEQEDEPTNKANPIASVDEE 1154

Query: 699  LENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELL-AKINHE---EQSKIQTQFGID 754
             E   +D   + + + QE ++   K E+    +  E    + NHE   E+ K + +   D
Sbjct: 1155 FEEVFKDEDREFEKHSQEELNREVKEEREFIPQKDETKDQESNHEDFEEEIKEEQKIDED 1214

Query: 755  AKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYS 814
               +E +   E ++++  +        E+   V +D+    E + D+      EKQ+   
Sbjct: 1215 TIKEEEEQKTEKVQNDFDEEIKEEDIKEKHEEVTKDKVEMNEEQNDE------EKQQQEV 1268

Query: 815  EYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQ 874
            E TI+ED +  +       ++ ++    E+++ + + +++++ + EE + + +++   Q 
Sbjct: 1269 ESTIEED-ITEQNVEPKKEEQTIQDFEEEVQNYDDKREEQSEKVHEERE-IVLNIEQPQ- 1325

Query: 875  HYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNT 934
                  E+  + +L E E  K   +L + E   K   HE +     KK+E+ + E +   
Sbjct: 1326 ------EEEKKEELHEEEEKK--EELHE-EEEKKEELHEEE-----KKEELHEEEKKEEQ 1371

Query: 935  QIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQ 994
              E     K+ L+E+ E+ IE + + E + + ++   +   ++ EE  K   +L ++  +
Sbjct: 1372 LHEEEEETKEELHEEEEEKIEKLHEEEKKEELHEEEKKEEQLHEEEEEKKEEQLHEEEEK 1431

Query: 995  KQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFT 1054
            K++    +  E+   E  K     ++++E+   L+++    +   +    + + +  +  
Sbjct: 1432 KEELHEEEKKEELHEEEKKEELHEEEEEEKKEELHEEEEEEKKEELHEEEEKKEEEEEKI 1491

Query: 1055 TKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMII 1114
             KL   EEE +   K+ L  ++  E+ + L  E++ + +E ++ +   E    K E    
Sbjct: 1492 EKLHEEEEEEK---KEELHEEEEEEKKEELHEEEEKKEEEEEKIEKLHEEEEKKKEQTNE 1548

Query: 1115 SSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTK 1174
                 P   +    +               ++EE+F  E++  +E   K   E  E   K
Sbjct: 1549 EINYNPAIKEVEGPESEEENKYR-------KDEEDFEDEKN--EESDYKKQKEESESVAK 1599

Query: 1175 IIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFE 1234
              +LE  +TE   +   NQE+ NQ K     L   + N+     E    ++   D   FE
Sbjct: 1600 --ELEETSTENRNN---NQEETNQPK-----LENSSLNITEVKEETEEKVNITDD---FE 1646

Query: 1235 IAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTS 1294
                 +    + +A+ +K  H+   Q+   +   E+ +++ +   ++E  K    E+   
Sbjct: 1647 TEN--QNEDRETDAETEKAIHQENEQIREKDFHDEKQIENEEE--KQEILKEPIEERNFQ 1702

Query: 1295 LQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRT 1354
             +N  +D EE  +  +E+  + +++ E    ++ +E+                   + + 
Sbjct: 1703 QENDFKDNEEEEKKEEEEKIEKLHEKEEKIEKLHEEE----------EKKEELHEEEEKK 1752

Query: 1355 ENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDS 1414
            E Q +++ +++  L+  E+  +L +                   E K  E  H+ E K+ 
Sbjct: 1753 EEQLHEEEEKKEELHEEEKKEELHEEEKKEELHEEEKKEEQLHEEEKKEEQLHEEEKKEE 1812

Query: 1415 EIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDL-TYEKESELAILRLKMHENANHY 1473
            +++++  +      ++  E E   +QL E EK+ E L   EK+ EL     K  E  +  
Sbjct: 1813 QLHEEEKK-----EEQLHEEEKKEEQLHEEEKKEEQLHEEEKKEELHEEEEKKEEQLHEE 1867

Query: 1474 ETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEI 1533
            E  +KE ++      EE   ++ E     +Q  E    +EE++ +  E +   E   I  
Sbjct: 1868 EEEKKEEQLHEE---EEKKEELHEEEKKEEQPHEEVVVVEEKMEQPQEEEEDNEADGIHS 1924

Query: 1534 VTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKE 1579
            ++  DE  + +  V     + +++  F ++ ++  +E+L+  + +E
Sbjct: 1925 LSDFDEEISTEEKVEIKVQEKEENNDFDAEEEKILEEKLEKEIIEE 1970



 Score = 83.0 bits (196), Expect = 6e-14
 Identities = 215/1110 (19%), Positives = 434/1110 (39%), Gaps = 90/1110 (8%)

Query: 534  KLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRM 593
            +L L++  ++ +  S+VS S       +E+L H+S    E +EE  + +    +  S R 
Sbjct: 411  RLSLRRSSESSNQSSQVSSSR------SEKLPHISSSRKE-KEEISSSRKEKEEISSSRK 463

Query: 594  IESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSD 653
             + ++     E E ++ +R +   +  S+K    +E+   +++ +E+     +  ++ S 
Sbjct: 464  EKEEISSSRKEKEEISSSRKEKEEISSSRKEK--EEISSSRKEKEEISSSRKEKEEISSS 521

Query: 654  QV-CSEIKSVHLE-EQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQ 711
            +    EI S   E E+I +    K+   L + N+   K   +  +++   ++E  + K  
Sbjct: 522  RKEKEEISSSRKEKEEISSSRKEKENTQLGLSNIIKGKLSTFD-VEEKPKEREFEVKKSS 580

Query: 712  NYIQENMDLTDKLEKMSAEKISE-LLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESE 770
                +N ++  ++   S  + ++   ++   EE SK +  F  +  I       E  +++
Sbjct: 581  EEENKNNEIPSEIITESYNETNDDFESEKPKEEVSKSENDFESEKHIDSAQKESEKEQAK 640

Query: 771  LSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQK----------AYSEYTIQE 820
             S+  S +    ES    E  +   E   D+L    QEK K             + T  E
Sbjct: 641  QSEETSNLESEFESEKHKESSKEETESDNDKLSDKKQEKDKETDDDFEEEGKKDQITQSE 700

Query: 821  DELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISL-----SDMQQH 875
            +E +N + +  + D+  +   +E +  N E+Q   +   EE  + +  L      D QQ 
Sbjct: 701  EEKLNEI-ISSEGDKEKDFHFIEEKKPNNEIQDDFEEATEEKYSEREELMKPTEPDFQQE 759

Query: 876  --YNALVEKANRTDLAES---ESTKYQTQLRDLE--SNLKRITHEHQTLIVQKKKEIEDL 928
                  V +  + D  E+   E TK + Q+ +++   ++K    E Q  I  +    E+ 
Sbjct: 760  EKQKEEVNEEKQIDRKENDFLEETK-EEQIHEVKVSDDIKDDFKEEQKEIEHESNNAEES 818

Query: 929  EIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLE- 987
              +    +     + KV  ++ E   E  T+ E    EYK   E  + N EE+ +   E 
Sbjct: 819  TNKSKEVVSETEEESKVQTKERENPSEEETKEEPFEDEYKE--ETKDENTEEIKEEPFED 876

Query: 988  ---LIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVS 1044
                 +K   K++T+  +  E    E        K++ +E      K  N + +      
Sbjct: 877  ETKEENKDKNKEETKEEEPFEDETKEEEPFEDENKEETKEETKEENKDENKEETKEEEPF 936

Query: 1045 DYESKLAQFTTKLENMEEEMQRVSKQLL--DSKQHNEELQILVREQDDQIK-ELKETKLT 1101
            + E+K        E  +EE +  SK+    ++K   +E +    E  ++ K E KE    
Sbjct: 937  EDETKEENKDENKEETKEETKDKSKEETKEETKDETKEEEPFDGETKEENKDENKEENKD 996

Query: 1102 FEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQS 1161
                  K E    +   EP  D+                  + +EEE F  E    +E++
Sbjct: 997  ENKEETKEENKEETKEEEPFEDETKEETKDETKEETKD---ETKEEEPFEDES---KEET 1050

Query: 1162 AKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLK-SKLEQLNTENDNLLSTVAEL 1220
             + N +  +  TK    E    E    D   +E   + K  +  +  T+ +N      E 
Sbjct: 1051 KEENKDENKEETKEETKEETKEEEPFEDENKEETKEETKEDEPFEDETKEENKEEEPFED 1110

Query: 1221 RSSISSAVDQR-GFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSST 1279
             +   +  D +  +E     + ++ ++E +     + +      FE  ++      +  +
Sbjct: 1111 ENKEETKEDNKDDYEEETKHENNVQEQEDEPTNKANPIASVDEEFEEVFKDEDREFEKHS 1170

Query: 1280 QEETNKIVTME--------QVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSE-IE-- 1328
            QEE N+ V  E        +    ++  +D EE ++  Q+   D I + E  ++E ++  
Sbjct: 1171 QEELNREVKEEREFIPQKDETKDQESNHEDFEEEIKEEQKIDEDTIKEEEEQKTEKVQND 1230

Query: 1329 -DEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQE-QSIL--NINEENAQLKKSSXXX 1384
             DE++                      +N   KQ QE +S +  +I E+N + KK     
Sbjct: 1231 FDEEIKEEDIKEKHEEVTKDKVEMNEEQNDEEKQQQEVESTIEEDITEQNVEPKKEEQT- 1289

Query: 1385 XXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEY 1444
                      + D E +V     + E +  ++++   E  I L     + E  +++L E 
Sbjct: 1290 ----------IQDFEEEVQNYDDKREEQSEKVHE---EREIVLNIEQPQEEEKKEELHEE 1336

Query: 1445 EKRIEDLTYEKESELAI----LRLKMHENANHYETMQKESEIERVKLIEELNVKITESVS 1500
            E++ E+L  E+E +  +     + ++HE     E + +E E  + +L EE   KI E + 
Sbjct: 1337 EEKKEELHEEEEKKEELHEEEKKEELHEEEKKEEQLHEEEEETKEELHEEEEEKI-EKLH 1395

Query: 1501 LNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEI--TNLQNMVRASSSKIQKHV 1558
              ++  EL++  ++E     E +   E Q  E     +E+     +  +     K + H 
Sbjct: 1396 EEEKKEELHEEEKKEEQLHEEEEEKKEEQLHEEEEKKEELHEEEKKEELHEEEKKEELHE 1455

Query: 1559 SFASDTKQGRDEQLDNTMNKELLDAVPRAE 1588
                + K+   E+ +    +EL +   + E
Sbjct: 1456 EEEEEKKEELHEEEEEEKKEELHEEEEKKE 1485


>UniRef50_Q6RT24 Cluster: Centromere associated protein-E; n=13;
            Eutheria|Rep: Centromere associated protein-E - Mus
            musculus (Mouse)
          Length = 2474

 Score =  130 bits (314), Expect = 3e-28
 Identities = 288/1427 (20%), Positives = 606/1427 (42%), Gaps = 149/1427 (10%)

Query: 244  ESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPS 303
            E++D+++  L+E N+L E    E   E  +  Q + +                 Q +E  
Sbjct: 523  ENEDLKLK-LKEKNELEEFELLEQKEERDQEMQLMHEVSNLKNLIKHAEEY--NQDLEND 579

Query: 304  CEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESK--AVSS 361
               K ++ ++   +I N+ E     +  E +   +  T+   E+    M T S    V+ 
Sbjct: 580  LSSKVKLLKEKEEQIKNLQEYIDA-QKSEKMKIDLSYTSDATEDLKQAMRTLSDLDTVAL 638

Query: 362  PSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEI-AKLEMVIQSLNKD 420
             +KK S  +     R+   ++K   ++LS      ++D ++ + ++ AK +M       D
Sbjct: 639  DAKKESAFL-----RSENLELKEKINELSDSRKQMESDIQMYQRQLEAKKKM-----QTD 688

Query: 421  LVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAK 480
            L DKE  ++ ++           G   L++ L+LE +          +    +++N+ A+
Sbjct: 689  L-DKELQLAFQEISKLSALVDGKG---LLSNLELEKR----------ITDLQKELNKEAE 734

Query: 481  VQEQLKQELN--DEIKDV--NVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLK 536
             ++ L++E+N   E+K +   V+ L  +L    E++  +  E +     M    S  +  
Sbjct: 735  EKQTLQEEVNLLSELKSLPSEVETLRRELYEKSEELHIITTEREKLFSEMAHKDSRIQGL 794

Query: 537  LKQMQKTIDNF--SKVSDSNKEIV-RLTEELH-HLSQKVAELEEEKGNLQLHLVDYDSGR 592
            L+++  T D+   S++S    +   +  E LH  L  + A + EE+  L+  +       
Sbjct: 795  LEEIGNTRDDLATSQLSRRGSDGEWQALESLHAELEHRHAGVLEERERLKQEI------G 848

Query: 593  MIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQS 652
             +  +       ++++          LE +  +  + L+ ++   +E+E + + +  ++ 
Sbjct: 849  ALSKEAESLAFSLDSVKAELSHKTQELEQKTVEGQERLNKMEALREELESRDSSLQSVEK 908

Query: 653  DQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLEN----DKEDIMN 708
            ++V    K     +++ AL+  KK L  + E+L+ +++QL   I+D  N     +E ++N
Sbjct: 909  EKVLLTEKLQQALKEVKALTQEKKNLKQLQESLQTERDQLRSDIQDTVNMNIDTQEQLLN 968

Query: 709  KLQNYIQENMDLTDKLEKMSAEKISE-LLAKINHEEQSKIQTQF-GIDAKIQE-RDLYIE 765
             L++ ++++ +  + L+  +AE++S+ L  K     + + Q +  GID + +    L   
Sbjct: 969  ALES-LKQHQETINMLKMKAAEELSDNLHVKDRGGARDEAQQKMDGIDEQNESAHTLLGG 1027

Query: 766  NIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKA----YSEYTIQED 821
              ++E+++ + +I  L +  + ++    S+  + +QL   L+E  +       E  I  D
Sbjct: 1028 GKDNEVTEEQRKIDSLMQENSGLQQTLESVRAEKEQLKMDLKENIEMSIENQEELRILRD 1087

Query: 822  ELVNRLAV-LMDHDRVVEK-QLL------------EIEHENKELQKKNQILL---EENQN 864
            EL  +  V   + D   EK Q L            ++E +N++LQ+  Q LL   E    
Sbjct: 1088 ELKRQQEVAAQEKDHATEKTQELSRTQERLAKTEEKLEEKNQKLQETQQQLLSTQEAMSK 1147

Query: 865  LQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTL-IVQKKK 923
            LQ  + DM+   N    +    +  E+E  +   +L +    +K IT E   L  +Q+  
Sbjct: 1148 LQAKVIDMESLQNEFRNQGLALERVETEKLELAQRLHESYEEVKSITKERNDLKELQESF 1207

Query: 924  EIEDLEI-EFNTQIES-AIRDKKVLNEKYEKNIEY---VTQLEAQLQEYK---NNIENLN 975
            EIE  ++ E+  +IE+  ++ K+ LN  +    EY   +T+L   + E +    + ++  
Sbjct: 1208 EIEKKQLKEYAREIEAEGLQAKEELNIAHANLKEYQEIITELRGSISENEAQGASTQDTA 1267

Query: 976  MNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNA------LLKQKDEEI--IA 1027
             +  EL     EL+++ +     ++    E+ +N +  + A       +  +  EI  + 
Sbjct: 1268 KSAPELQGEVPELLEQELLPVVKEARHSAEK-VNGLEPVGAHSRTVHSMTMEGIEIGNLR 1326

Query: 1028 LNQKINNAQVSYMSMVSDYES-KLAQFTTKLE--NMEEEMQRVSKQLLDSKQHNEELQIL 1084
            L +K+  +Q+    +  + E  +  Q T ++E   ++E+ +R     L++++     +  
Sbjct: 1327 LTKKLEESQMEISCLTREREDLRRTQETLQVECTQLKEDARRTLANHLETEEELNLARCC 1386

Query: 1085 VREQDDQIKELKETKLTFEMNIPKTEGMIISST------IEPMSDDANNVDXXXXXXXXX 1138
            ++EQ+++I  L  +    E  +    G +  +T      ++ + +    +          
Sbjct: 1387 LKEQENKIDTLITSLSQRETELSSVRGQLALTTAELERKVQELCEKQEELTRKETSEAQG 1446

Query: 1139 XXXLKVQEEEEFIQERSVLQEQSA---KLNTELQECYTKI-------IQLETLNTELTGH 1188
                  Q  E  + + S LQ   +   +LNT+L+E   ++        +L  +   L   
Sbjct: 1447 KMSELEQLRELLLAQASALQNAESDRLRLNTQLEESQEEMKTLREEREELRRMQEALHVE 1506

Query: 1189 DVVNQEQINQLKSKLEQL-NTENDNL-LSTVAELRSSISSAVD--QRGFEIAELWKQHLA 1244
                +E + ++ SKL++L N E + L + T+ E + S    +D   +  E  +   + + 
Sbjct: 1507 SEQQKESMKEISSKLQELQNKEYECLAMKTINETQGS-RCEMDHLNQQLEAQKSTLEKVE 1565

Query: 1245 QREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEE 1304
                +  +  HE   ++ +   + ++L    +  T E      ++E+  +   K  +KEE
Sbjct: 1566 MENVNLTQRLHETLEEMRSVAKERDELWSMEERLTVERDQLKKSLEETVT---KGMEKEE 1622

Query: 1305 HLRNLQ---EKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQ 1361
             LR      E++ + IN++  + S+  DE                    DLR +     Q
Sbjct: 1623 ELRVAHVHLEEHQETINKLRKMVSDYTDEISHTQGDLKHTNAVVEAQNQDLREKEHQLSQ 1682

Query: 1362 MQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQL--ELKDSEIYQK 1419
            + +  +    ++  QLKK               +   E + LELT QL   LK   +  K
Sbjct: 1683 V-KADLRETVDQMEQLKKK-------LEAQSSTLESREIEKLELTQQLNENLKKITLVTK 1734

Query: 1420 THEYTITLTQR-NDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENA--NHYETM 1476
             ++    + +   +E + +R+ L + E R  DL  +++  +A + LK H+       ETM
Sbjct: 1735 ENDSLKIMDEALREERDQLRKSLQQTEAR--DLENQEKLRIAHMNLKEHQETIDRLMETM 1792

Query: 1477 -QKESEIERVKL-IEELNVKITESV----SLNKQVAELNKALEEEVAKTNEMQTALENQE 1530
             +K  EI  +K+ +E +N+K+ E V    +  +Q  +L     E   +  E    L   E
Sbjct: 1793 SEKTEEISNMKMELENVNMKLQEKVQELKTSERQRVKLKADASEAKKELKEQGLTLSKIE 1852

Query: 1531 IEIVTLNDEI-TNLQNM--VRASSSKIQKHVSFASDTKQGRDEQLDN 1574
            +E + L  +I  NL+ M  VR     ++K        +  RD+  DN
Sbjct: 1853 MENLNLAQKIHENLEEMKSVRKERDDLKK---LEEILRMERDQLKDN 1896



 Score =  127 bits (307), Expect = 2e-27
 Identities = 258/1307 (19%), Positives = 539/1307 (41%), Gaps = 111/1307 (8%)

Query: 337  QIRQTNKELENKLAT-MGTESKAVSSPSKKGSPLISRKSGRNTASK----MKSPWSQLSS 391
            +++ +N E E K+ T + T  +  S  S + + L+  K G + AS     + +    L+ 
Sbjct: 427  KMKDSNYEKEFKVPTSITTRKRKTSVTSLRENSLM--KFGESAASSEFEMLNNTLESLAE 484

Query: 392  ETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQ 451
               +  T     +N  ++L  +    N  ++D E +  E +            ++  + +
Sbjct: 485  VEWSSATTLLSEENVESELNSLNAQYNDLVLDYEQLRRENEDLKLKLKEKNELEEFELLE 544

Query: 452  LQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQ 511
             + E  Q M+   L+H  +N ++   + K  E+  Q+L +++        ++ LK  EEQ
Sbjct: 545  QKEERDQEMQ---LMHEVSNLKN---LIKHAEEYNQDLENDLSSK-----VKLLKEKEEQ 593

Query: 512  ITQLNDEIDAANKNMIKVK----SNHKLKLKQMQKTIDNFSKVS-DSNKEIVRLTEELHH 566
            I  L + IDA     +K+     S+    LKQ  +T+ +   V+ D+ KE   L  E   
Sbjct: 594  IKNLQEYIDAQKSEKMKIDLSYTSDATEDLKQAMRTLSDLDTVALDAKKESAFLRSENLE 653

Query: 567  LSQKVAELEEEK----GNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQ 622
            L +K+ EL + +     ++Q++    ++ + +++D+ K++     LA   +  +S L   
Sbjct: 654  LKEKINELSDSRKQMESDIQMYQRQLEAKKKMQTDLDKEL----QLAFQEISKLSALVDG 709

Query: 623  KFDLVQELHILQQKYD---EVEDKLADISQLQSD-QVCSEIKSVHLEEQIDALSASKKEL 678
            K  L+  L + ++  D   E+  +  +   LQ +  + SE+KS  L  +++ L     E 
Sbjct: 710  K-GLLSNLELEKRITDLQKELNKEAEEKQTLQEEVNLLSELKS--LPSEVETLRRELYEK 766

Query: 679  ALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQE--NMDLTDKLEKMSAEKISELL 736
            +  +  +  ++E+L+  +   ++  + ++ ++ N   +     L+ +      + +  L 
Sbjct: 767  SEELHIITTEREKLFSEMAHKDSRIQGLLEEIGNTRDDLATSQLSRRGSDGEWQALESLH 826

Query: 737  AKINH------EEQSKIQTQFGIDAKIQERDLY-IENIESELSKYKSRICRLEESIAVME 789
            A++ H      EE+ +++ + G  +K  E   + ++++++ELS +K++   LE+     +
Sbjct: 827  AELEHRHAGVLEERERLKQEIGALSKEAESLAFSLDSVKAELS-HKTQ--ELEQKTVEGQ 883

Query: 790  DRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVL--MDHDRVVEKQLLE-IEH 846
            +R   +E   ++L S     Q    E  +  ++L   L  +  +  ++   KQL E ++ 
Sbjct: 884  ERLNKMEALREELESRDSSLQSVEKEKVLLTEKLQQALKEVKALTQEKKNLKQLQESLQT 943

Query: 847  ENKELQKKNQILLEEN----QNLQISLSDMQQHY---NALVEKANRTDLAESESTKYQTQ 899
            E  +L+   Q  +  N    + L  +L  ++QH    N L  KA   +L+++   K +  
Sbjct: 944  ERDQLRSDIQDTVNMNIDTQEQLLNALESLKQHQETINMLKMKAAE-ELSDNLHVKDRGG 1002

Query: 900  LRD-LESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVT 958
             RD  +  +  I  ++++         ++   E   +I+S +++   L +  E       
Sbjct: 1003 ARDEAQQKMDGIDEQNESAHTLLGGGKDNEVTEEQRKIDSLMQENSGLQQTLESVRAEKE 1062

Query: 959  QLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALL 1018
            QL+  L+E   NIE    N EEL  +  EL  K  Q+   Q  D+  +   E+++    L
Sbjct: 1063 QLKMDLKE---NIEMSIENQEELRILRDEL--KRQQEVAAQEKDHATEKTQELSRTQERL 1117

Query: 1019 KQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEE-------MQRVSKQL 1071
             + +E++   NQK+   Q   +S   +  SKL      +E+++ E       ++RV  + 
Sbjct: 1118 AKTEEKLEEKNQKLQETQQQLLS-TQEAMSKLQAKVIDMESLQNEFRNQGLALERVETEK 1176

Query: 1072 LDSKQ--HN--EELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANN 1127
            L+  Q  H   EE++ + +E++D +KEL+E+    E    K     I +      ++ N 
Sbjct: 1177 LELAQRLHESYEEVKSITKERND-LKELQES-FEIEKKQLKEYAREIEAEGLQAKEELNI 1234

Query: 1128 VDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNT---- 1183
                          L+    E   Q  S   + +AK   ELQ    ++++ E L      
Sbjct: 1235 AHANLKEYQEIITELRGSISENEAQGAST--QDTAKSAPELQGEVPELLEQELLPVVKEA 1292

Query: 1184 -----ELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRG------ 1232
                 ++ G + V           +E +   N  L   + E +  IS    +R       
Sbjct: 1293 RHSAEKVNGLEPVGAHSRTVHSMTMEGIEIGNLRLTKKLEESQMEISCLTREREDLRRTQ 1352

Query: 1233 ----FEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVT 1288
                 E  +L K+   +  A+  +TE EL +     + +  ++   + S +Q ET     
Sbjct: 1353 ETLQVECTQL-KEDARRTLANHLETEEELNLARCCLKEQENKIDTLITSLSQRETELSSV 1411

Query: 1289 MEQVTSLQNKLQDKEEHLRNLQEKYA-DVINQIEILRSEIEDEKVAFXXXXXXXXXXXXX 1347
              Q+     +L+ K + L   QE+      ++ +   SE+E  +                
Sbjct: 1412 RGQLALTTAELERKVQELCEKQEELTRKETSEAQGKMSELEQLRELLLAQASALQNAESD 1471

Query: 1348 XXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTH 1407
                LR   Q  +  +E   L   EE  +L++               + +  +K+ EL +
Sbjct: 1472 R---LRLNTQLEESQEEMKTLR--EEREELRRMQEALHVESEQQKESMKEISSKLQELQN 1526

Query: 1408 -QLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKM 1466
             + E    +   +T      +   N + E  +  L + E    +LT      L  +R   
Sbjct: 1527 KEYECLAMKTINETQGSRCEMDHLNQQLEAQKSTLEKVEMENVNLTQRLHETLEEMRSVA 1586

Query: 1467 HENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTAL 1526
             E    + +M++   +ER +L + L   +T+ +   +++   +  LEE     N+++  +
Sbjct: 1587 KERDELW-SMEERLTVERDQLKKSLEETVTKGMEKEEELRVAHVHLEEHQETINKLRKMV 1645

Query: 1527 ENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLD 1573
             +   EI     ++ +   +V A +  +++     S  K    E +D
Sbjct: 1646 SDYTDEISHTQGDLKHTNAVVEAQNQDLREKEHQLSQVKADLRETVD 1692



 Score = 97.9 bits (233), Expect = 2e-18
 Identities = 231/1148 (20%), Positives = 480/1148 (41%), Gaps = 101/1148 (8%)

Query: 477  EIAKVQEQLKQELNDEIKDVNV-KDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSN--- 532
            EIA +++QL +E+N + +   + KD + +L   ++ + ++ DE     K M+   S+   
Sbjct: 351  EIADLRKQL-EEVNTKTRAQEMEKDQLAQLLDEKDLLQKVQDEKINNLKRMLVTSSSIAL 409

Query: 533  -HKLKLKQMQKTIDNFSKVSDSNKEI-VRLTEELHHLSQKVAELEEEKGNLQLHLVDYDS 590
              +L++K+ ++    + K+ DSN E   ++   +    +K +     + +L        S
Sbjct: 410  QQELEIKRKRRVTWCYGKMKDSNYEKEFKVPTSITTRKRKTSVTSLRENSLMKFGESAAS 469

Query: 591  GRM-IESDVYKKMIEMENLAETRLKA-------ISLLESQKFDLVQELHILQQKYDEVED 642
                + ++  + + E+E  + T L +       ++ L +Q  DLV +   L+++ ++++ 
Sbjct: 470  SEFEMLNNTLESLAEVEWSSATTLLSEENVESELNSLNAQYNDLVLDYEQLRRENEDLKL 529

Query: 643  KLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLEND 702
            KL + ++L+  ++  + +    E Q+    ++ K L    E    D E    +   L  +
Sbjct: 530  KLKEKNELEEFELLEQKEERDQEMQLMHEVSNLKNLIKHAEEYNQDLENDLSSKVKLLKE 589

Query: 703  KEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDL 762
            KE+ +  LQ YI        K++       +E L K      S + T   +DAK +   L
Sbjct: 590  KEEQIKNLQEYIDAQKSEKMKIDLSYTSDATEDL-KQAMRTLSDLDT-VALDAKKESAFL 647

Query: 763  YIENIESELSKYKSRICRLEESIAVMED--RRY--SLERKADQLGSYLQEKQKAYSEYTI 818
              EN+E      K +I  L +S   ME   + Y   LE K        +E Q A+ E + 
Sbjct: 648  RSENLE-----LKEKINELSDSRKQMESDIQMYQRQLEAKKKMQTDLDKELQLAFQEIS- 701

Query: 819  QEDELVNRLAVLMDHDRVVEKQLLEIEHE-NKELQKKNQILLEEN--QNLQISLSDMQQH 875
            +   LV+   +L + +  +EK++ +++ E NKE ++K  +  E N    L+   S+++  
Sbjct: 702  KLSALVDGKGLLSNLE--LEKRITDLQKELNKEAEEKQTLQEEVNLLSELKSLPSEVETL 759

Query: 876  YNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHE-----HQTLIVQKKKEIEDLEI 930
               L EK+    +  +E  K  +++   +S ++ +  E           Q  +   D E 
Sbjct: 760  RRELYEKSEELHIITTEREKLFSEMAHKDSRIQGLLEEIGNTRDDLATSQLSRRGSDGEW 819

Query: 931  EFNTQIESAI--RDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLEL 988
            +    + + +  R   VL E+ E+  + +  L  + +    +++++     EL+    EL
Sbjct: 820  QALESLHAELEHRHAGVLEER-ERLKQEIGALSKEAESLAFSLDSVK---AELSHKTQEL 875

Query: 989  IDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYES 1048
              K V+ Q+  +    E    E+   ++ L+  ++E + L +K+  A +  +  ++  + 
Sbjct: 876  EQKTVEGQERLNK--MEALREELESRDSSLQSVEKEKVLLTEKLQQA-LKEVKALTQEKK 932

Query: 1049 KLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPK 1108
             L Q     E+++ E  ++   + D+   N + Q  +    + +K+ +ET    +M   +
Sbjct: 933  NLKQLQ---ESLQTERDQLRSDIQDTVNMNIDTQEQLLNALESLKQHQETINMLKMKAAE 989

Query: 1109 --TEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQER----SVLQEQSA 1162
              ++ + +        +    +D            L   ++ E  +E+    S++QE S 
Sbjct: 990  ELSDNLHVKDRGGARDEAQQKMDGIDEQNESAHTLLGGGKDNEVTEEQRKIDSLMQENSG 1049

Query: 1163 KLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRS 1222
             L   L+    +  QL+    E     + NQE++  L+ +L++             E   
Sbjct: 1050 -LQQTLESVRAEKEQLKMDLKENIEMSIENQEELRILRDELKRQQEVAAQEKDHATEKTQ 1108

Query: 1223 SISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEE 1282
             +S   ++    +A+  ++ L ++    Q+T+ +L     A      +++D ++S   E 
Sbjct: 1109 ELSRTQER----LAKT-EEKLEEKNQKLQETQQQLLSTQEAMSKLQAKVID-MESLQNEF 1162

Query: 1283 TNKIVTMEQVTS----LQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXX 1338
             N+ + +E+V +    L  +L +  E ++++ ++     N ++ L+   E EK       
Sbjct: 1163 RNQGLALERVETEKLELAQRLHESYEEVKSITKER----NDLKELQESFEIEKKQLKEYA 1218

Query: 1339 XXXXXXXXXXXXDLRTENQSYKQMQE---QSILNINEENAQLKKSSXXXXXXXXXXXXRV 1395
                        +L   + + K+ QE   +   +I+E  AQ   +               
Sbjct: 1219 REIEAEGLQAKEELNIAHANLKEYQEIITELRGSISENEAQGASTQDTAKSAPELQGEVP 1278

Query: 1396 NDAEAKVL----ELTHQLELKDSEIYQKTHEYTI-TLTQRNDEFENVR--QQLVEYEKRI 1448
               E ++L    E  H  E  +       H  T+ ++T    E  N+R  ++L E +  I
Sbjct: 1279 ELLEQELLPVVKEARHSAEKVNGLEPVGAHSRTVHSMTMEGIEIGNLRLTKKLEESQMEI 1338

Query: 1449 EDLTYEKE------SELAILRLKMHEN-----ANHYETMQ---------KESEIERVKLI 1488
              LT E+E        L +   ++ E+     ANH ET +         KE E +   LI
Sbjct: 1339 SCLTREREDLRRTQETLQVECTQLKEDARRTLANHLETEEELNLARCCLKEQENKIDTLI 1398

Query: 1489 EELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEI-EIVTLNDEITNLQNMV 1547
              L+ + TE  S+  Q+A     LE +V +  E Q  L  +E  E      E+  L+ ++
Sbjct: 1399 TSLSQRETELSSVRGQLALTTAELERKVQELCEKQEELTRKETSEAQGKMSELEQLRELL 1458

Query: 1548 RASSSKIQ 1555
             A +S +Q
Sbjct: 1459 LAQASALQ 1466



 Score = 88.2 bits (209), Expect = 2e-15
 Identities = 166/859 (19%), Positives = 337/859 (39%), Gaps = 81/859 (9%)

Query: 750  QFGIDAKIQERDLYIENIESE---LSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYL 806
            QF   AK  +   Y+  + ++   L +Y+  I  L + +  +  +  + E + DQL   L
Sbjct: 321  QFASTAKYMKNTPYVNEVSNDEALLKRYRREIADLRKQLEEVNTKTRAQEMEKDQLAQLL 380

Query: 807  QEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKE---LQKKNQILLEENQ 863
             EK        +Q++++ N   +L+    +  +Q LEI+ + +      K      E+  
Sbjct: 381  DEKDLLQK---VQDEKINNLKRMLVTSSSIALQQELEIKRKRRVTWCYGKMKDSNYEKEF 437

Query: 864  NLQISLSDMQQHYNALVEKANR-TDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKK 922
             +  S++  ++  +    + N      ES ++     L +   +L  +     T ++ ++
Sbjct: 438  KVPTSITTRKRKTSVTSLRENSLMKFGESAASSEFEMLNNTLESLAEVEWSSATTLLSEE 497

Query: 923  KEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELN 982
                +L    N Q    + D + L  + E +++   + + +L+E+    E L    E   
Sbjct: 498  NVESELN-SLNAQYNDLVLDYEQLRRENE-DLKLKLKEKNELEEF----ELLEQKEERDQ 551

Query: 983  KMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYM-- 1040
            +M L     +++     + +Y +   N+++    LLK+K+E+I  L + I+  +   M  
Sbjct: 552  EMQLMHEVSNLKNLIKHAEEYNQDLENDLSSKVKLLKEKEEQIKNLQEYIDAQKSEKMKI 611

Query: 1041 --SMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELK-- 1096
              S  SD    L Q    L +++       K+    +  N EL+  + E  D  K+++  
Sbjct: 612  DLSYTSDATEDLKQAMRTLSDLDTVALDAKKESAFLRSENLELKEKINELSDSRKQMESD 671

Query: 1097 --------ETKLTFEMNIPKTEGMIIS--STIEPMSDD---ANNVDXXXXXXXXXXXXLK 1143
                    E K   + ++ K   +     S +  + D     +N++             K
Sbjct: 672  IQMYQRQLEAKKKMQTDLDKELQLAFQEISKLSALVDGKGLLSNLELEKRITDLQKELNK 731

Query: 1144 VQEEEEFIQER----SVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQL 1199
              EE++ +QE     S L+   +++ T  +E Y K  +L  + TE          + +++
Sbjct: 732  EAEEKQTLQEEVNLLSELKSLPSEVETLRRELYEKSEELHIITTEREKLFSEMAHKDSRI 791

Query: 1200 KSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRV 1259
            +  LE++    D+L ++    R S         ++  E     L  R A   +    L+ 
Sbjct: 792  QGLLEEIGNTRDDLATSQLSRRGSDGE------WQALESLHAELEHRHAGVLEERERLKQ 845

Query: 1260 QLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQ 1319
            ++ A   + E L  S+ S   E ++K   +EQ T    +  +K E LR   E     +  
Sbjct: 846  EIGALSKEAESLAFSLDSVKAELSHKTQELEQKTVEGQERLNKMEALREELESRDSSLQS 905

Query: 1320 IE---ILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTE-NQSYKQMQEQSILNINEENA 1375
            +E   +L +E   + +                   L+TE +Q    +Q+   +NI+ +  
Sbjct: 906  VEKEKVLLTEKLQQALKEVKALTQEKKNLKQLQESLQTERDQLRSDIQDTVNMNIDTQEQ 965

Query: 1376 QLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKD-----SEIYQK------THEYT 1424
             L                ++  AE    EL+  L +KD      E  QK       +E  
Sbjct: 966  LLNALESLKQHQETINMLKMKAAE----ELSDNLHVKDRGGARDEAQQKMDGIDEQNESA 1021

Query: 1425 ITL---------TQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYET 1475
             TL         T+   + +++ Q+    ++ +E +  EKE     L++ + EN      
Sbjct: 1022 HTLLGGGKDNEVTEEQRKIDSLMQENSGLQQTLESVRAEKEQ----LKMDLKENIEMSIE 1077

Query: 1476 MQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVT 1535
             Q+E  I R +L  +  V   E     ++  EL++  +E +AKT E    LE +  ++  
Sbjct: 1078 NQEELRILRDELKRQQEVAAQEKDHATEKTQELSRT-QERLAKTEE---KLEEKNQKLQE 1133

Query: 1536 LNDEITNLQNMVRASSSKI 1554
               ++ + Q  +    +K+
Sbjct: 1134 TQQQLLSTQEAMSKLQAKV 1152



 Score = 84.6 bits (200), Expect = 2e-14
 Identities = 175/885 (19%), Positives = 378/885 (42%), Gaps = 94/885 (10%)

Query: 242  DIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLA---KQ 298
            ++  +  +I SL + N  L+     +  E  +L  +L++              L    K+
Sbjct: 1032 EVTEEQRKIDSLMQENSGLQQTLESVRAEKEQLKMDLKENIEMSIENQEELRILRDELKR 1091

Query: 299  SIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKA 358
              E + +EK    EK          L K  E LE  N ++++T ++L   L+T       
Sbjct: 1092 QQEVAAQEKDHATEKTQELSRTQERLAKTEEKLEEKNQKLQETQQQL---LSTQ------ 1142

Query: 359  VSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLN 418
              + SK  + +I  +S +N          ++ +E L        +  E+  +      L 
Sbjct: 1143 -EAMSKLQAKVIDMESLQNEFRNQGLALERVETEKLELAQRLHESYEEVKSITKERNDLK 1201

Query: 419  KDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHV--GTNTEDVN 476
            +  + + + I +K            G      +L + H    E   +I    G+ +E+  
Sbjct: 1202 E--LQESFEIEKKQLKEYAREIEAEGLQAK-EELNIAHANLKEYQEIITELRGSISENEA 1258

Query: 477  EIAKVQEQLKQ--ELNDEIKDVNVKDLIEKLKSAEEQITQLND-EIDAANKNMIKVKSNH 533
            + A  Q+  K   EL  E+ ++  ++L+  +K A     ++N  E   A+   +   +  
Sbjct: 1259 QGASTQDTAKSAPELQGEVPELLEQELLPVVKEARHSAEKVNGLEPVGAHSRTVHSMTME 1318

Query: 534  KLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEE----KGNLQLHLVDYD 589
             +++  ++ T     K+ +S  EI  LT E   L +    L+ E    K + +  L ++ 
Sbjct: 1319 GIEIGNLRLT----KKLEESQMEISCLTREREDLRRTQETLQVECTQLKEDARRTLANHL 1374

Query: 590  SGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHI----LQQKYDEVEDKLA 645
                  +     + E EN  +T + ++S  E++   +  +L +    L++K  E+ +K  
Sbjct: 1375 ETEEELNLARCCLKEQENKIDTLITSLSQRETELSSVRGQLALTTAELERKVQELCEKQE 1434

Query: 646  DISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKED 705
            ++++ ++ +  ++ K   LE+  + L A     A  ++N + D+ +L   +++ + + + 
Sbjct: 1435 ELTRKETSE--AQGKMSELEQLRELLLAQ----ASALQNAESDRLRLNTQLEESQEEMKT 1488

Query: 706  IMNKLQNY--IQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLY 763
            +  + +    +QE + +  + +K S ++IS  L ++ ++E   +  +  I+ + Q     
Sbjct: 1489 LREEREELRRMQEALHVESEQQKESMKEISSKLQELQNKEYECLAMKT-IN-ETQGSRCE 1546

Query: 764  IENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYS---EYTIQE 820
            ++++  +L   KS + ++E     +  R   L    +++ S  +E+ + +S     T++ 
Sbjct: 1547 MDHLNQQLEAQKSTLEKVEMENVNLTQR---LHETLEEMRSVAKERDELWSMEERLTVER 1603

Query: 821  DELVNRLAVLMDHDRVVEKQL----LEIEHENKELQKKNQILLEENQNLQISLSDMQQHY 876
            D+L   L   +      E++L    + +E   + + K  +++ +    +  +  D++ H 
Sbjct: 1604 DQLKKSLEETVTKGMEKEEELRVAHVHLEEHQETINKLRKMVSDYTDEISHTQGDLK-HT 1662

Query: 877  NALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQI 936
            NA+VE  N+ DL E E      QL  ++++L+    + + L   KKK    LE + +T +
Sbjct: 1663 NAVVEAQNQ-DLREKEH-----QLSQVKADLRETVDQMEQL---KKK----LEAQSST-L 1708

Query: 937  ESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQ 996
            ES   +K  L ++  +N++ +T +  +    K   E L    ++L K            Q
Sbjct: 1709 ESREIEKLELTQQLNENLKKITLVTKENDSLKIMDEALREERDQLRK----------SLQ 1758

Query: 997  QTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTK 1056
            QT++ D   Q    I  +N  LK+  E I  L           M  +S+   +++    +
Sbjct: 1759 QTEARDLENQEKLRIAHMN--LKEHQETIDRL-----------METMSEKTEEISNMKME 1805

Query: 1057 LENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLT 1101
            LEN+  ++Q   ++L  S++   +L+    +  +  KELKE  LT
Sbjct: 1806 LENVNMKLQEKVQELKTSERQRVKLK---ADASEAKKELKEQGLT 1847



 Score = 69.7 bits (163), Expect = 6e-10
 Identities = 176/930 (18%), Positives = 390/930 (41%), Gaps = 85/930 (9%)

Query: 240  LKDIESK-DVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQ 298
            LK+ E+K D  I+SL +    L + R +++L  ++L +++++               A+ 
Sbjct: 1387 LKEQENKIDTLITSLSQRETELSSVRGQLALTTAELERKVQELCEKQEELTRKETSEAQG 1446

Query: 299  SIEPSCEEKTEI--EEKGSLEIANMTELTKKIELLEHLNCQ--IRQTNKELENKLATMGT 354
             +    E+  E+   +  +L+ A    L    +L E       +R+  +EL      +  
Sbjct: 1447 KMS-ELEQLRELLLAQASALQNAESDRLRLNTQLEESQEEMKTLREEREELRRMQEALHV 1505

Query: 355  ESKAVSSPSKKGSPLISRKSGRN---TASKM--KSPWSQLSSETLNQDTDKKINKNEIAK 409
            ES+      K+ S  +     +     A K   ++  S+   + LNQ  + + +  E  +
Sbjct: 1506 ESEQQKESMKEISSKLQELQNKEYECLAMKTINETQGSRCEMDHLNQQLEAQKSTLEKVE 1565

Query: 410  LEMV--IQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGP---- 463
            +E V   Q L++ L +   V  E+D            +D L   L+    + ME      
Sbjct: 1566 MENVNLTQRLHETLEEMRSVAKERDELWSMEERLTVERDQLKKSLEETVTKGMEKEEELR 1625

Query: 464  -SLIHVGTNTEDVNEIAKVQEQLKQELND---EIKDVN--VKDLIEKLKSAEEQITQLND 517
             + +H+  + E +N++ K+      E++    ++K  N  V+   + L+  E Q++Q+  
Sbjct: 1626 VAHVHLEEHQETINKLRKMVSDYTDEISHTQGDLKHTNAVVEAQNQDLREKEHQLSQVKA 1685

Query: 518  EIDAANKNMIKVKS-----NHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVA 572
            ++      M ++K      +  L+ ++++K ++   +++++ K+I  +T+E   L     
Sbjct: 1686 DLRETVDQMEQLKKKLEAQSSTLESREIEK-LELTQQLNENLKKITLVTKENDSLKIMDE 1744

Query: 573  ELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHI 632
             L EE+  L+  L   ++ R +E+    ++  M NL E +     L+E+   +  +E+  
Sbjct: 1745 ALREERDQLRKSLQQTEA-RDLENQEKLRIAHM-NLKEHQETIDRLMETMS-EKTEEISN 1801

Query: 633  LQQKYDEVEDKLAD-ISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDK-- 689
            ++ + + V  KL + + +L++    SE + V L+          KE  L +  ++++   
Sbjct: 1802 MKMELENVNMKLQEKVQELKT----SERQRVKLKADASEAKKELKEQGLTLSKIEMENLN 1857

Query: 690  --EQLYGTIKDLENDKE--DIMNKLQNYIQENMD-LTDKLEKMSAEKISELLAKINHEEQ 744
              ++++  ++++++ ++  D + KL+  ++   D L D L +      + L A  NHEE 
Sbjct: 1858 LAQKIHENLEEMKSVRKERDDLKKLEEILRMERDQLKDNLRE------AMLKAHQNHEET 1911

Query: 745  SKIQTQF-----GIDAKIQERDLYIENIESELSKYKSRI-CR------LEESIAVMEDRR 792
             K              +++E+   IE +    S+  +   C       LE      ++  
Sbjct: 1912 MKCGKGLLCAGEYCTGRLREKCFRIEKLLKRYSEMANDYECLNKVSLDLERETKTQKELS 1971

Query: 793  YSLERKADQLGSYLQEKQK---AYSEYTIQEDELVNRLA-VLMDHDRVVEKQLLEIEHEN 848
             ++  K     +  +E +K   A    +++    + RL  VL    R+ E+Q     HE+
Sbjct: 1972 VTVRTKLSLPHTQTKEMEKLLTANQRCSLEFHRALKRLKYVLSSIARIKEEQ-----HES 2026

Query: 849  KELQKKNQILLEENQN-LQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDL-ESN 906
               ++   I   E QN LQI +  + Q Y  +  +  +  L++      +  L+D  E++
Sbjct: 2027 INKREMAFIQEVEKQNELQIQIQSLSQTYR-IPARDLQIKLSQEMDLHIEEMLKDFSEND 2085

Query: 907  LKRITHEHQTLIVQKKKEIEDLEIEFNT-----QIESAIRDKK----VLNEKYEKNIEYV 957
               I  E Q ++  +K+  E L    NT      ++S I+ +     ++N  Y   I  +
Sbjct: 2086 FLTIKTEVQQVLNNRKEITEFLGKWLNTLFDTENLKSTIQKENKSIGLVNNFYHSRITAM 2145

Query: 958  TQLEAQLQEYK-NNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNA 1016
                 + +E      ++L+  ++ L +   +L + +     +QS  +    +    + + 
Sbjct: 2146 INESTEFEERSATRSKDLDQYLKSLKETTEQLSEVYQTLTASQSVVHLHPTVQPSTRDSE 2205

Query: 1017 LLKQKD-EEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSK 1075
              +     E +    KI    V Y   + D + +L +   + +   +E  +    L  + 
Sbjct: 2206 RPQAASGAEQLTSKNKIALGAVPYKEEIEDLKMQLVKSDLEKKATAKEFDKKILSLKATV 2265

Query: 1076 QHNEELQILVREQDDQIKELKETKLTFEMN 1105
            +H EE+  L+RE     ++ ++T +  E +
Sbjct: 2266 EHQEEMIRLLRENLRGHQQAQDTSMISEQD 2295



 Score = 68.9 bits (161), Expect = 1e-09
 Identities = 207/1056 (19%), Positives = 451/1056 (42%), Gaps = 99/1056 (9%)

Query: 305  EEKTEIEE-KGSLEIANMTELTKKI-ELLEHLNCQIRQTNKELENKLATMGTESKAVSSP 362
            + +TE+   +G L +    EL +K+ EL E      R+   E + K++ +    + + + 
Sbjct: 1403 QRETELSSVRGQLALTT-AELERKVQELCEKQEELTRKETSEAQGKMSELEQLRELLLA- 1460

Query: 363  SKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLN-KDL 421
              + S L + +S R   +      SQ   +TL ++ ++     E   +E   Q  + K++
Sbjct: 1461 --QASALQNAESDRLRLNTQLEE-SQEEMKTLREEREELRRMQEALHVESEQQKESMKEI 1517

Query: 422  VDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEH-QQHMEGPSLIHVGTNTEDVNEIAK 480
              K   +  K+             +T  ++ +++H  Q +E           E+VN   +
Sbjct: 1518 SSKLQELQNKEYECLAMKTI---NETQGSRCEMDHLNQQLEAQKSTLEKVEMENVNLTQR 1574

Query: 481  VQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQ-LNDEIDAANKNMIKVKSNHKLKLKQ 539
            + E L++  +   +   +  + E+L    +Q+ + L + +    +   +++  H + L++
Sbjct: 1575 LHETLEEMRSVAKERDELWSMEERLTVERDQLKKSLEETVTKGMEKEEELRVAH-VHLEE 1633

Query: 540  MQKTIDNFSK-VSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDV 598
             Q+TI+   K VSD   EI     +L H +  V     E  N  L   ++   + +++D+
Sbjct: 1634 HQETINKLRKMVSDYTDEISHTQGDLKHTNAVV-----EAQNQDLREKEHQLSQ-VKADL 1687

Query: 599  YKKMIEMENLAETRLKAISLLES---QKFDLVQELHILQQKYDEV---EDKLADISQLQS 652
             + + +ME L +      S LES   +K +L Q+L+   +K   V    D L  + +   
Sbjct: 1688 RETVDQMEQLKKKLEAQSSTLESREIEKLELTQQLNENLKKITLVTKENDSLKIMDEALR 1747

Query: 653  DQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQN 712
            ++     KS+   E  D  +  K  +A +  NLK  +E +   ++ +    E+I N    
Sbjct: 1748 EERDQLRKSLQQTEARDLENQEKLRIAHM--NLKEHQETIDRLMETMSEKTEEISNMKME 1805

Query: 713  YIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGID-AKIQERDLYI-----EN 766
                NM L +K++++   +   +  K +  E  K   + G+  +KI+  +L +     EN
Sbjct: 1806 LENVNMKLQEKVQELKTSERQRVKLKADASEAKKELKEQGLTLSKIEMENLNLAQKIHEN 1865

Query: 767  IESELSKYKSR--ICRLEESIAVMEDR-RYSLERKADQLGSYLQEKQKA---------YS 814
            +E   S  K R  + +LEE + +  D+ + +L     +     +E  K          Y 
Sbjct: 1866 LEEMKSVRKERDDLKKLEEILRMERDQLKDNLREAMLKAHQNHEETMKCGKGLLCAGEYC 1925

Query: 815  EYTIQE-----DELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISL 869
               ++E     ++L+ R + + +    + K  L++E E K  QK+    L      ++SL
Sbjct: 1926 TGRLREKCFRIEKLLKRYSEMANDYECLNKVSLDLERETK-TQKE----LSVTVRTKLSL 1980

Query: 870  SDMQ-QHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHE-HQTLIVQKKKEIED 927
               Q +    L+    R  L    + K   +L+ + S++ RI  E H+++  ++   I++
Sbjct: 1981 PHTQTKEMEKLLTANQRCSLEFHRALK---RLKYVLSSIARIKEEQHESINKREMAFIQE 2037

Query: 928  LEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQL-QEYKNNIENLNMNVEELNKMNL 986
            +E +   QI+      + L++ Y         L+ +L QE   +IE +  +  E + + +
Sbjct: 2038 VEKQNELQIQI-----QSLSQTYRIP---ARDLQIKLSQEMDLHIEEMLKDFSENDFLTI 2089

Query: 987  ELIDKHVQKQQTQSPDYTEQYIN---EINKLNALLKQKDEEIIALNQKINNAQVSYMSMV 1043
            +   + V   + +  ++  +++N   +   L + ++++++ I  +N   ++   + ++  
Sbjct: 2090 KTEVQQVLNNRKEITEFLGKWLNTLFDTENLKSTIQKENKSIGLVNNFYHSRITAMINES 2149

Query: 1044 SDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFE 1103
            +++E + A  +  L+   + ++  ++QL      +E  Q L   Q      +     T +
Sbjct: 2150 TEFEERSATRSKDLDQYLKSLKETTEQL------SEVYQTLTASQ-----SVVHLHPTVQ 2198

Query: 1104 MNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQE---- 1159
             +   +E    +S  E ++   N +             LK+Q  +  +++++  +E    
Sbjct: 2199 PSTRDSERPQAASGAEQLT-SKNKIALGAVPYKEEIEDLKMQLVKSDLEKKATAKEFDKK 2257

Query: 1160 -QSAKLNTELQECYTKIIQLETLNTELTGHDV-VNQEQINQLKSKLEQLNTENDNLLSTV 1217
              S K   E QE   ++++ E L       D  +  EQ +QL SK       +  + ST 
Sbjct: 2258 ILSLKATVEHQEEMIRLLR-ENLRGHQQAQDTSMISEQDSQLLSKPLTCGGGSGIVQSTK 2316

Query: 1218 AELRSSISSAVDQRGFEIAELWKQHLAQREADFQ--KTEHELRVQLSAFESKYEQLLDSV 1275
            A +   + S   + G EI++L +Q+   R+ + Q      +L  ++  +E +  +  DS 
Sbjct: 2317 ALI---LKSEYKRMGSEISKLKQQNEQLRKQNNQLLSDNSQLSNEVKTWEERTLK-RDSY 2372

Query: 1276 QSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQE 1311
            + +T E + K   + +  S + +    +   +NLQ+
Sbjct: 2373 RETTCENSPKSPKVTRTDSKRRQNTTSQCRAQNLQD 2408


>UniRef50_Q9BJD3 Cluster: Major plasmodial myosin heavy chain; n=3;
            Physarum polycephalum|Rep: Major plasmodial myosin heavy
            chain - Physarum polycephalum (Slime mold)
          Length = 2148

 Score =  130 bits (314), Expect = 3e-28
 Identities = 266/1312 (20%), Positives = 538/1312 (41%), Gaps = 104/1312 (7%)

Query: 147  LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXX 206
            L   +KE ++ ++ LQ  +K  +  +++LQ+   +  Q I    +               
Sbjct: 872  LERQLKEAEHKIAQLQDSLKAEKANVVNLQDANADLKQEIATHERKIANLESELSEQTKL 931

Query: 207  XXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFE 266
                    K+  TK++E   A++ E +D +  L K     D  +  +++ +         
Sbjct: 932  LDSITVARKEAETKVKELTTALQDE-RDARLNLEKAKRKVDDELDEVKKQHDFDVERIAN 990

Query: 267  ISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTK 326
            +    ++L  E+E+              L KQ  +   + + ++E K + E+   TEL+K
Sbjct: 991  LEKLKNELQAEVEELSDQFADETKSRASLEKQKRKIDSDLE-DLENKYNEEVTQRTELSK 1049

Query: 327  -KIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSP 385
             K +L   L     Q   E+E +    G + K  ++ + + + L   +  RN   K K  
Sbjct: 1050 LKNQLDSDLRSTTSQLESEIERRGILEGLQKKLEAALASETAKLEEEQKNRNALEKAKKA 1109

Query: 386  WSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGK 445
              Q   +   +  D+K N++   K     + L+ DL +    +  K            G 
Sbjct: 1110 LEQQQRDLTQELQDEKKNRDTAEKAR---KKLDLDLTELRDQLDVK-----------GGD 1155

Query: 446  DTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELND---EIKDVNVK--D 500
               +A L+ + +Q +E      V    + V+ + K++  L+ +LND    + + N +  +
Sbjct: 1156 VKALADLKQKVEQELEDLRR-QVEELKKAVSNLEKIKRTLEAQLNDANNALAESNAENAN 1214

Query: 501  LIEKLKSAEEQITQLNDEIDAANKN---MIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEI 557
            L +  K  EE +  LN ++    ++   + K K      +K+++  ++N S    +  + 
Sbjct: 1215 LTKLKKKLEEDLVALNQKLAEEQRDKAALDKAKKKADQDVKELKSNLENVSASRATLDQN 1274

Query: 558  VRLTEELHHLSQKVAELE-EEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAI 616
            ++ TEE   L     ELE E+K   QL      + +++E++++     ++   +   K  
Sbjct: 1275 LKATEE--KLENAKVELEQEQKTKQQLE----KAKKLLETELH----AVQGQLDDEKKGR 1324

Query: 617  SLLESQKFDLVQELHILQQKYDE---VEDKLADI-SQLQSDQVCSEIKSVHLEEQIDALS 672
             +++ ++ DL  EL  L++ ++E       + D  S+LQSD    E+K +    + DA +
Sbjct: 1325 DIVDRKRSDLESELADLREDFEEALSARKVIGDAKSKLQSDY--EELKKI---AESDAAA 1379

Query: 673  ASK-KELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKL--EKMSA 729
              K +E   ++E    D + L   ++D E   E I  + +    +  D+ +KL  E+ + 
Sbjct: 1380 RQKAQEQVKILELQNADSQSL---VQDAEAAAEKIERQRRTLEADLQDVQEKLDEEQKAR 1436

Query: 730  EKISELLAKINHE-EQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVM 788
             +  + LAK + E  Q+K++    +     ++ + ++ ++ E S     +  L+E  A  
Sbjct: 1437 VRFQKQLAKTDEELRQAKLKID-DLTNATSDQYIALKRLQEENSNQHRELEALDEKTAQW 1495

Query: 789  EDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHEN 848
               R   E + + L + L+E   A  +   Q+ +L N++    D +   +     +  + 
Sbjct: 1496 NRLRKQAEVQLEDLKAQLEEAISAKLKVEKQKRDLENKVE---DLESAADVNSANVHPD- 1551

Query: 849  KELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLK 908
             EL+KK Q + E  +  Q++    ++  +  V++  R D+   E       + + E N  
Sbjct: 1552 -ELRKKQQEVDELKK--QLAAEQERKTKDEEVKRQLRKDVTTQEEA-----IEEYERN-- 1601

Query: 909  RITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYK 968
            ++  E     ++KK E E  +++ + + E  +R K  L  K  +  E  T+++  +    
Sbjct: 1602 KLNAER----IRKKLENELEDLKASLESEQILRKKAELLAK-PRGKEGATEIKPTVSSKS 1656

Query: 969  NNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIAL 1028
            +  E+     EEL  +  EL     +K    + +  E+ +   N  + L  Q ++E+ A 
Sbjct: 1657 D--EDFKKLTEELAVLKTEL---DGEKAWRGNAEKRERALRAEN--DELRGQLEDEVTA- 1708

Query: 1029 NQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNE---ELQILV 1085
              K N A+ +    V + + +L +    L+  EE  +R   +L + K+  E   EL + +
Sbjct: 1709 KDKTNKAKRALEVEVEELKDQLDEVEESLQEAEEFKRRKDLELEEVKRKLEGEAELTLKM 1768

Query: 1086 REQDDQI-KELKETKLTF-EMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLK 1143
             E   Q  K+++  K+   E    + E   I   +E  +DD N                K
Sbjct: 1769 DELRKQFEKDIENLKVELEEERRSRGEAERIRKRLEAENDDLNIKLDAEIKTRQKTEKAK 1828

Query: 1144 VQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKL 1203
             + E EF   R+ L E+SA   T+ +    K+ +      E   ++V  +  I + +  L
Sbjct: 1829 KKIEGEFRATRTRLDEESA-TKTQSENLAQKLEEEIAKLKEDLDNEVKQKALIERTRKSL 1887

Query: 1204 EQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSA 1263
            E    +    +   A  R++      Q   E+ +L +Q  A  E +      + R+++  
Sbjct: 1888 ELQLEDTRTQMEVEARQRANADKLRRQAENELEDLREQVDAFDETEQDLLSDKTRLEVEC 1947

Query: 1264 FESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLR-NLQE-------KYAD 1315
             E++   L +S ++    E  +     ++  L+ K  D+E  LR NL+         Y D
Sbjct: 1948 EEARKNVLRES-EAREAAELARTRIQRELAELREK-YDEEVILRTNLERTRKKTDADYED 2005

Query: 1316 VINQIEI---LRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINE 1372
               Q+E+   LR+++E E V                   L+   Q+ ++M E     +  
Sbjct: 2006 AKEQLELESKLRAKLERE-VKAAAAGTKLLQTAKADADKLKARVQALEKM-EADYKKLQA 2063

Query: 1373 ENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLE--LKDSEIYQKTHE 1422
               + + +              +N+A A VL    Q E    D E  +K++E
Sbjct: 2064 RCTEEEDARRAAENEKKKAIADLNEARADVLFYQQQAEKIRTDVEKEKKSNE 2115



 Score = 98.7 bits (235), Expect = 1e-18
 Identities = 218/1102 (19%), Positives = 457/1102 (41%), Gaps = 85/1102 (7%)

Query: 451  QLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNV-KDLIEKL-KSA 508
            Q +LE     E   L     N   + +  K  EQ +++L  E++D    +D  EK  K  
Sbjct: 1079 QKKLEAALASETAKLEEEQKNRNALEKAKKALEQQQRDLTQELQDEKKNRDTAEKARKKL 1138

Query: 509  EEQITQLNDEIDAAN---KNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTE-EL 564
            +  +T+L D++D      K +  +K   + +L+ +++ ++   K   + ++I R  E +L
Sbjct: 1139 DLDLTELRDQLDVKGGDVKALADLKQKVEQELEDLRRQVEELKKAVSNLEKIKRTLEAQL 1198

Query: 565  HHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKF 624
            +  +  +AE   E  NL          + +E D+    +  +   E R KA   L+  K 
Sbjct: 1199 NDANNALAESNAENANLT------KLKKKLEEDLVA--LNQKLAEEQRDKAA--LDKAKK 1248

Query: 625  DLVQELHILQQKYDEVEDKLADISQ-LQSDQVCSEIKSVHLEEQIDALSASKKELALVIE 683
               Q++  L+   + V    A + Q L++ +   E   V LE++      +K++L    +
Sbjct: 1249 KADQDVKELKSNLENVSASRATLDQNLKATEEKLENAKVELEQE----QKTKQQLEKAKK 1304

Query: 684  NLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEK-MSAEK-ISELLAKI-- 739
             L+ +   + G + D +  ++ +  K  +   E  DL +  E+ +SA K I +  +K+  
Sbjct: 1305 LLETELHAVQGQLDDEKKGRDIVDRKRSDLESELADLREDFEEALSARKVIGDAKSKLQS 1364

Query: 740  NHEEQSKI-QTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERK 798
            ++EE  KI ++      K QE+   ++ +E + +  +S +   E +   +E +R +LE  
Sbjct: 1365 DYEELKKIAESDAAARQKAQEQ---VKILELQNADSQSLVQDAEAAAEKIERQRRTLEAD 1421

Query: 799  ADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQIL 858
               +   L E+QKA   +  Q       LA   +  R  + ++ ++ +   +     + L
Sbjct: 1422 LQDVQEKLDEEQKARVRFQKQ-------LAKTDEELRQAKLKIDDLTNATSDQYIALKRL 1474

Query: 859  LEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLI 918
             EEN N         +   AL EK  + +    ++   + QL DL++ L+        + 
Sbjct: 1475 QEENSN-------QHRELEALDEKTAQWNRLRKQA---EVQLEDLKAQLEEAISAKLKVE 1524

Query: 919  VQKK---KEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLN 975
             QK+    ++EDLE      + SA      L +K ++  E   QL A+ QE K   E + 
Sbjct: 1525 KQKRDLENKVEDLESA--ADVNSANVHPDELRKKQQEVDELKKQLAAE-QERKTKDEEVK 1581

Query: 976  MNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLK-----QKDEEIIALNQ 1030
              + +      E I+++ ++ +  +    ++  NE+  L A L+     +K  E++A  +
Sbjct: 1582 RQLRKDVTTQEEAIEEY-ERNKLNAERIRKKLENELEDLKASLESEQILRKKAELLAKPR 1640

Query: 1031 KINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDD 1090
                A     ++ S  +    + T +L  ++ E+          + + E+ +  +R ++D
Sbjct: 1641 GKEGATEIKPTVSSKSDEDFKKLTEELAVLKTELDGEKAW----RGNAEKRERALRAEND 1696

Query: 1091 QIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEF 1150
            +++   E ++T +    K +   +   +E + D  + V+             K  E EE 
Sbjct: 1697 ELRGQLEDEVTAKDKTNKAK-RALEVEVEELKDQLDEVEESLQEAEEFKRR-KDLELEEV 1754

Query: 1151 IQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTEN 1210
             ++     E + K++ EL++ + K   +E L  EL   +  ++ +  +++ +LE    EN
Sbjct: 1755 KRKLEGEAELTLKMD-ELRKQFEK--DIENLKVELE-EERRSRGEAERIRKRLE---AEN 1807

Query: 1211 DNL-LSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHE-LRVQLSAFESKY 1268
            D+L +   AE+++   +   ++  E  E         E    KT+ E L  +L    +K 
Sbjct: 1808 DDLNIKLDAEIKTRQKTEKAKKKIE-GEFRATRTRLDEESATKTQSENLAQKLEEEIAKL 1866

Query: 1269 EQLLDSV--QSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSE 1326
            ++ LD+   Q +  E T K + + Q+   + +++ +     N  +      N++E LR +
Sbjct: 1867 KEDLDNEVKQKALIERTRKSLEL-QLEDTRTQMEVEARQRANADKLRRQAENELEDLREQ 1925

Query: 1327 IE--DEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXX 1384
            ++  DE                             ++  E +   I  E A+L++     
Sbjct: 1926 VDAFDETEQDLLSDKTRLEVECEEARKNVLRESEAREAAELARTRIQRELAELREKYDEE 1985

Query: 1385 XXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEY 1444
                          +A   +   QLEL +S++  K               +  +    + 
Sbjct: 1986 VILRTNLERTRKKTDADYEDAKEQLEL-ESKLRAKLEREVKAAAAGTKLLQTAKADADKL 2044

Query: 1445 EKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQ 1504
            + R++ L  + E++   L+ +  E     E  ++ +E E+ K I +LN    + +   +Q
Sbjct: 2045 KARVQALE-KMEADYKKLQARCTEE----EDARRAAENEKKKAIADLNEARADVLFYQQQ 2099

Query: 1505 VAELNKALEEEVAKTNEMQTAL 1526
              ++   +E+E     ++Q  L
Sbjct: 2100 AEKIRTDVEKEKKSNEDLQANL 2121



 Score = 95.1 bits (226), Expect = 1e-17
 Identities = 203/994 (20%), Positives = 422/994 (42%), Gaps = 90/994 (9%)

Query: 590  SGRMIESDVYKKMIEMENLAETRL--KAISLLESQKFDLVQELHILQQKYDEVEDKLADI 647
            S R+I+ ++ +  +E +N A  +L  KA  LL  +  D  +EL     +  ++  +LA  
Sbjct: 809  SARIIQDNI-RAYLEFKNWAWWKLFAKARPLLVGRNMD--KELKERDSQIKDLSSQLAAE 865

Query: 648  ----SQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDK 703
                ++L+     +E K   L++ + A  A+   L     +LK +       I +LE++ 
Sbjct: 866  KAARAELERQLKEAEHKIAQLQDSLKAEKANVVNLQDANADLKQEIATHERKIANLESEL 925

Query: 704  EDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLY 763
             +    L +      +   K+++++     E  A++N E+ +K +    +D   ++ D  
Sbjct: 926  SEQTKLLDSITVARKEAETKVKELTTALQDERDARLNLEK-AKRKVDDELDEVKKQHDFD 984

Query: 764  IE---NIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQE 820
            +E   N+E   ++ ++ +  L +  A     R SLE++  ++ S L++ +  Y+E   Q 
Sbjct: 985  VERIANLEKLKNELQAEVEELSDQFADETKSRASLEKQKRKIDSDLEDLENKYNEEVTQR 1044

Query: 821  DELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQIS-LSDMQQHYNAL 879
             EL ++L   +D D       LE E E + + +  Q  LE     + + L + Q++ NAL
Sbjct: 1045 TEL-SKLKNQLDSDLRSTTSQLESEIERRGILEGLQKKLEAALASETAKLEEEQKNRNAL 1103

Query: 880  VEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEI--------- 930
             EKA +    E +      +L+D + N        + L +   +  + L++         
Sbjct: 1104 -EKAKKA--LEQQQRDLTQELQDEKKNRDTAEKARKKLDLDLTELRDQLDVKGGDVKALA 1160

Query: 931  EFNTQIESAIRDKKVLNEKYEK---NIEYVTQ-LEAQLQEYKN-----NIENLNMN---- 977
            +   ++E  + D +   E+ +K   N+E + + LEAQL +  N     N EN N+     
Sbjct: 1161 DLKQKVEQELEDLRRQVEELKKAVSNLEKIKRTLEAQLNDANNALAESNAENANLTKLKK 1220

Query: 978  --VEELNKMNLELIDKH-----VQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQ 1030
               E+L  +N +L ++      + K + ++    ++  + +  ++A     D+ + A  +
Sbjct: 1221 KLEEDLVALNQKLAEEQRDKAALDKAKKKADQDVKELKSNLENVSASRATLDQNLKATEE 1280

Query: 1031 KINNAQVSYMSMVSDYESKLAQFTTKLEN-MEEEMQRVSKQLLDSKQHNEELQILVREQD 1089
            K+ NA+V       + E K  Q   K +  +E E+  V  QL D K+  +   I+ R++ 
Sbjct: 1281 KLENAKVEL-----EQEQKTKQQLEKAKKLLETELHAVQGQLDDEKKGRD---IVDRKRS 1332

Query: 1090 DQIKELKETKLTFE--MNIPKTEG---MIISSTIEPMSDDANNVDXXXXXXXXXXXXLKV 1144
            D   EL + +  FE  ++  K  G     + S  E +   A +              L++
Sbjct: 1333 DLESELADLREDFEEALSARKVIGDAKSKLQSDYEELKKIAESDAAARQKAQEQVKILEL 1392

Query: 1145 Q--EEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSK 1202
            Q  + +  +Q+     E+  +    L E   + +Q E L+ E     V  Q+Q+ +   +
Sbjct: 1393 QNADSQSLVQDAEAAAEKIERQRRTL-EADLQDVQ-EKLDEEQKAR-VRFQKQLAKTDEE 1449

Query: 1203 LEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLS 1262
            L Q   + D+L +  ++   ++    ++   +  EL  + L ++ A + +   +  VQL 
Sbjct: 1450 LRQAKLKIDDLTNATSDQYIALKRLQEENSNQHREL--EALDEKTAQWNRLRKQAEVQLE 1507

Query: 1263 AFESKYEQLLDS---VQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQ 1319
              +++ E+ + +   V+   ++  NK+  +E    + N      + LR  Q++  ++  Q
Sbjct: 1508 DLKAQLEEAISAKLKVEKQKRDLENKVEDLESAADV-NSANVHPDELRKKQQEVDELKKQ 1566

Query: 1320 IEILRS-EIEDEKVAFXXXXXXXXXXXXXXXXD---LRTENQSYKQMQEQSILNINEENA 1375
            +   +  + +DE+V                  +   L  E    K   E   L  + E+ 
Sbjct: 1567 LAAEQERKTKDEEVKRQLRKDVTTQEEAIEEYERNKLNAERIRKKLENELEDLKASLESE 1626

Query: 1376 QL--KKSSXXXXXXXXXXXXRV-----NDAEAKVLELTHQLELKDSEI-YQKTHEYTITL 1427
            Q+  KK+              +     + ++    +LT +L +  +E+  +K        
Sbjct: 1627 QILRKKAELLAKPRGKEGATEIKPTVSSKSDEDFKKLTEELAVLKTELDGEKAWRGNAEK 1686

Query: 1428 TQRNDEFEN--VRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHY-ETMQKESEIER 1484
             +R    EN  +R QL E E   +D T + +  L +   ++ +  +   E++Q+  E +R
Sbjct: 1687 RERALRAENDELRGQL-EDEVTAKDKTNKAKRALEVEVEELKDQLDEVEESLQEAEEFKR 1745

Query: 1485 VK--LIEELNVKITESVSLNKQVAELNKALEEEV 1516
             K   +EE+  K+     L  ++ EL K  E+++
Sbjct: 1746 RKDLELEEVKRKLEGEAELTLKMDELRKQFEKDI 1779



 Score = 87.8 bits (208), Expect = 2e-15
 Identities = 149/786 (18%), Positives = 328/786 (41%), Gaps = 59/786 (7%)

Query: 811  KAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLS 870
            K   E   Q  +L ++LA        +E+QL E EH+  +LQ   +       NLQ + +
Sbjct: 846  KELKERDSQIKDLSSQLAAEKAARAELERQLKEAEHKIAQLQDSLKAEKANVVNLQDANA 905

Query: 871  DMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEI 930
            D++Q       K    +   SE TK    +       +    E  T +  ++    +LE 
Sbjct: 906  DLKQEIATHERKIANLESELSEQTKLLDSITVARKEAETKVKELTTALQDERDARLNLE- 964

Query: 931  EFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELID 990
            +   +++  + + K   ++++ ++E +  LE    E +  +E L+    +  K    L +
Sbjct: 965  KAKRKVDDELDEVK---KQHDFDVERIANLEKLKNELQAEVEELSDQFADETKSRASL-E 1020

Query: 991  KHVQKQQTQSPDYTEQYINEINK---LNALLKQKDEEIIALNQKINNAQVSYMSMVSDYE 1047
            K  +K  +   D   +Y  E+ +   L+ L  Q D ++ +   ++ + ++    ++   +
Sbjct: 1021 KQKRKIDSDLEDLENKYNEEVTQRTELSKLKNQLDSDLRSTTSQLES-EIERRGILEGLQ 1079

Query: 1048 SKL-AQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNI 1106
             KL A   ++   +EEE Q+    L  +K+  E+ Q   R+   ++++ K+ + T E   
Sbjct: 1080 KKLEAALASETAKLEEE-QKNRNALEKAKKALEQQQ---RDLTQELQDEKKNRDTAEKAR 1135

Query: 1107 PKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNT 1166
             K + + ++   + +     +V              KV++E E ++ R V + + A  N 
Sbjct: 1136 KKLD-LDLTELRDQLDVKGGDVKALADLKQ------KVEQELEDLR-RQVEELKKAVSNL 1187

Query: 1167 ELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISS 1226
            E  +  T   QL   N  L   +  N   + +LK KLE+     +  L+     ++++  
Sbjct: 1188 EKIK-RTLEAQLNDANNALAESNAENAN-LTKLKKKLEEDLVALNQKLAEEQRDKAALDK 1245

Query: 1227 AVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKI 1286
            A  +   ++ EL K +L    A     +  L+      E+   +L    ++  Q E  K 
Sbjct: 1246 AKKKADQDVKEL-KSNLENVSASRATLDQNLKATEEKLENAKVELEQEQKTKQQLEKAKK 1304

Query: 1287 VTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXX 1346
            +   ++ ++Q +L D+++    +  K +D+ +++  LR + E+   A             
Sbjct: 1305 LLETELHAVQGQLDDEKKGRDIVDRKRSDLESELADLREDFEEALSA--------RKVIG 1356

Query: 1347 XXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELT 1406
                 L+++ +  K++ E       +   Q+K                V DAEA   ++ 
Sbjct: 1357 DAKSKLQSDYEELKKIAESDAAARQKAQEQVK----ILELQNADSQSLVQDAEAAAEKIE 1412

Query: 1407 HQ---LELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILR 1463
             Q   LE    ++ +K  E      +   +     ++L + + +I+DLT     +   L+
Sbjct: 1413 RQRRTLEADLQDVQEKLDEEQKARVRFQKQLAKTDEELRQAKLKIDDLTNATSDQYIALK 1472

Query: 1464 LKMHENANHYETM----QKESEIERVK-----LIEELNVKITESVSLNKQVAELNKALEE 1514
                EN+N +  +    +K ++  R++      +E+L  ++ E++S   +V +  + LE 
Sbjct: 1473 RLQEENSNQHRELEALDEKTAQWNRLRKQAEVQLEDLKAQLEEAISAKLKVEKQKRDLEN 1532

Query: 1515 EVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDN 1574
               K  ++++A +     +    DE+   Q  V     +++K ++ A   ++ +DE++  
Sbjct: 1533 ---KVEDLESAADVNSANVHP--DELRKKQQEV----DELKKQLA-AEQERKTKDEEVKR 1582

Query: 1575 TMNKEL 1580
             + K++
Sbjct: 1583 QLRKDV 1588



 Score = 86.6 bits (205), Expect = 5e-15
 Identities = 235/1213 (19%), Positives = 492/1213 (40%), Gaps = 126/1213 (10%)

Query: 143  DVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXX 202
            +V  LS+   ++  + + L+ + + +++ + DL+ K NE+           T        
Sbjct: 1001 EVEELSDQFADETKSRASLEKQKRKIDSDLEDLENKYNEE----------VTQRTELSKL 1050

Query: 203  XXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEA 262
                       T Q  ++++   I      +  +++L   + S+  ++   ++    LE 
Sbjct: 1051 KNQLDSDLRSTTSQLESEIERRGIL-----EGLQKKLEAALASETAKLEEEQKNRNALEK 1105

Query: 263  ARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEE-KTEIEEKGSLEIANM 321
            A+  +  +   L QEL+                A++ ++    E + +++ KG  ++  +
Sbjct: 1106 AKKALEQQQRDLTQELQDEKKNRDTAEK-----ARKKLDLDLTELRDQLDVKGG-DVKAL 1159

Query: 322  TELTKKIEL-LEHLNCQIRQTNKELENKLATMGT-ESKAVSSPSKKGSPLISRKSGRNTA 379
             +L +K+E  LE L  Q+ +  K + N      T E++   + +          +     
Sbjct: 1160 ADLKQKVEQELEDLRRQVEELKKAVSNLEKIKRTLEAQLNDANNALAESNAENANLTKLK 1219

Query: 380  SKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXX 439
             K++     L+ +   +  DK        K +  ++ L  +L +     +  D       
Sbjct: 1220 KKLEEDLVALNQKLAEEQRDKAALDKAKKKADQDVKELKSNLENVSASRATLDQNLKATE 1279

Query: 440  XXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELND-EIKDVNV 498
                     + Q Q   QQ  +   L+          E+  VQ QL  E    +I D   
Sbjct: 1280 EKLENAKVELEQEQKTKQQLEKAKKLLE--------TELHAVQGQLDDEKKGRDIVDRKR 1331

Query: 499  KDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIV 558
             DL  +L    E      +E  +A K +   KS  +   ++++K  ++ +      +E V
Sbjct: 1332 SDLESELADLREDF----EEALSARKVIGDAKSKLQSDYEELKKIAESDAAARQKAQEQV 1387

Query: 559  RLTEELHHLSQKV---AELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKA 615
            ++ E  +  SQ +   AE   EK   Q   ++ D       DV +K+ E E  A  R + 
Sbjct: 1388 KILELQNADSQSLVQDAEAAAEKIERQRRTLEADL-----QDVQEKLDE-EQKARVRFQK 1441

Query: 616  ISLLESQKFDLVQELHILQQKYDEVEDKLAD----ISQLQSDQVCSEIKSVHLEEQIDAL 671
                +  K D  +EL   + K D++ +  +D    + +LQ +      +   L+E+    
Sbjct: 1442 ----QLAKTD--EELRQAKLKIDDLTNATSDQYIALKRLQEENSNQHRELEALDEKTAQW 1495

Query: 672  SASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEK 731
            +  +K+  + +E+LK   E+       +E  K D+ NK++       DL    +  SA  
Sbjct: 1496 NRLRKQAEVQLEDLKAQLEEAISAKLKVEKQKRDLENKVE-------DLESAADVNSANV 1548

Query: 732  ISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDR 791
              + L K   +E  +++ Q   +   QER    E ++ +L K    +   EE+I   E  
Sbjct: 1549 HPDELRK-KQQEVDELKKQLAAE---QERKTKDEEVKRQLRK---DVTTQEEAIEEYERN 1601

Query: 792  RYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKEL 851
            + + ER   +L + L++ +      +++ ++++ + A L+   R  E         + + 
Sbjct: 1602 KLNAERIRKKLENELEDLKA-----SLESEQILRKKAELLAKPRGKEGATEIKPTVSSKS 1656

Query: 852  QKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRIT 911
             +  + L EE   L+  L D ++ +    EK  R   AE++  + + QL D E   K  T
Sbjct: 1657 DEDFKKLTEELAVLKTEL-DGEKAWRGNAEKRERALRAEND--ELRGQLED-EVTAKDKT 1712

Query: 912  HEHQTLIVQKKKEIEDL--EIEFNTQIESAIRDKKVLN-EKYEKNIEYVTQLEAQLQE-- 966
            ++ +  +  + +E++D   E+E + Q     + +K L  E+ ++ +E   +L  ++ E  
Sbjct: 1713 NKAKRALEVEVEELKDQLDEVEESLQEAEEFKRRKDLELEEVKRKLEGEAELTLKMDELR 1772

Query: 967  --YKNNIENLNMNVEE--LNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKD 1022
              ++ +IENL + +EE   ++   E I K ++ +        +  I    K     K+ +
Sbjct: 1773 KQFEKDIENLKVELEEERRSRGEAERIRKRLEAENDDLNIKLDAEIKTRQKTEKAKKKIE 1832

Query: 1023 EEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKL-ENMEEEMQRVSKQLLDSKQHNEEL 1081
             E  A   +++    +  +   +   KL +   KL E+++ E+++  K L++  + + EL
Sbjct: 1833 GEFRATRTRLDEESAT-KTQSENLAQKLEEEIAKLKEDLDNEVKQ--KALIERTRKSLEL 1889

Query: 1082 QILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXX 1141
            Q+      +  +   E +     N  K       + +E + +  +  D            
Sbjct: 1890 QL------EDTRTQMEVEARQRANADKLRRQ-AENELEDLREQVDAFDETEQDLLSDKTR 1942

Query: 1142 LKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKS 1201
            L+V+ EE     ++VL+E  A+   EL    T+I +      E    +V+ +  + + + 
Sbjct: 1943 LEVECEE---ARKNVLRESEAREAAELAR--TRIQRELAELREKYDEEVILRTNLERTRK 1997

Query: 1202 KLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQL 1261
            K +    +    L   ++LR+ +     +R  + A    + L   +AD  K +  ++  L
Sbjct: 1998 KTDADYEDAKEQLELESKLRAKL-----EREVKAAAAGTKLLQTAKADADKLKARVQA-L 2051

Query: 1262 SAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVI---N 1318
               E+ Y++L    Q+   EE +     E          +K++ + +L E  ADV+    
Sbjct: 2052 EKMEADYKKL----QARCTEEEDARRAAE---------NEKKKAIADLNEARADVLFYQQ 2098

Query: 1319 QIEILRSEIEDEK 1331
            Q E +R+++E EK
Sbjct: 2099 QAEKIRTDVEKEK 2111


>UniRef50_A0ECU5 Cluster: Chromosome undetermined scaffold_9, whole
            genome shotgun sequence; n=3; Paramecium tetraurelia|Rep:
            Chromosome undetermined scaffold_9, whole genome shotgun
            sequence - Paramecium tetraurelia
          Length = 1851

 Score =  130 bits (314), Expect = 3e-28
 Identities = 251/1278 (19%), Positives = 563/1278 (44%), Gaps = 109/1278 (8%)

Query: 377  NTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXX 436
            N + +  + +     E L QD  K   K  I +L+   Q L K +  + Y + +K     
Sbjct: 40   NLSGRKSTLFEDKRYEELLQDNRKL--KEVIEQLDKDNQQL-KQMSGESYNLKQKYMIAQ 96

Query: 437  XXXXXXXGK-DTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKD 495
                    +   L +QL + + Q  E  +L  V    +DV+ + + Q Q +QE++     
Sbjct: 97   AELEAAQQELAKLRSQLLMRNSQDAEQSTL--VTRYKQDVSTLTQQQIQYQQEISQ---- 150

Query: 496  VNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNK 555
              +  L+E+ +   E+  +L  + +   +       N +++++Q+++      + S +  
Sbjct: 151  --LNALLEQQRKQVEEFLRLKSKYEQDVQTYRSRAQNLEIEIRQVKE-----QRNSTTQN 203

Query: 556  EIVRLTEELHHLSQKVAELEEEKGNLQLHLVDY-DSGRMIESDVYKKMIEMENLAETRLK 614
            EI+RLT+E+     +V     +K   +  +    D  + +++D+ + +IE +N  + +L+
Sbjct: 204  EIIRLTQEIARYQSEVQVRSSDKELYERTISTLNDKIKEMDNDI-QILIEAQNQNQYKLE 262

Query: 615  AI-----SLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQID 669
            +      S ++ Q   L QE+   Q +  + ++K   + ++Q ++  SE + + +E +I+
Sbjct: 263  SAMAESKSNMQYQIDQLKQEMTFYQTQCKQWQEKCQTV-EMQKEE--SERRIIQMEIRIN 319

Query: 670  ALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTD----KLE 725
                +KK++    +N K+ +E     I  ++N+ E    K   YI   + + D    +++
Sbjct: 320  E---TKKQIEQQ-QNDKVQRESYQ--IHTIQNELESWKQK---YISLEIKMKDYDNYRMQ 370

Query: 726  KMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERD----LYIENIES------ELSKYK 775
             +  E+ S      N + + +++       ++QE++    L I  +ES      E  +YK
Sbjct: 371  LIQLEEQSNFYKNENDQMKEELEILIAEIKQLQEQNNGYRLSITQLESQARNSVENDRYK 430

Query: 776  SRICRLEESIAVMEDR--RYSLERKA-DQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMD 832
            S+I  LE +I  +  +   Y +E K  +Q   Y Q K         +++E +++L   ++
Sbjct: 431  SQIRNLENTINQLNQQINAYKIETKELEQQVIYHQNKNTNVDYQVREKEETISKLQYKLN 490

Query: 833  HD----RVVEKQLLEIEHENKELQKKNQI---LLEENQNLQISLSDMQQHYNALVEKANR 885
            +     RV+ ++ L+IE ++ + QK+ QI   L +  +  +  +S ++QH+++L E  N+
Sbjct: 491  NMEKELRVIFEEQLKIEKQDWDRQKQQQIDDQLQKITKKYESEISTLRQHFSSL-EIENQ 549

Query: 886  TDLAESESTKYQTQL---RDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRD 942
            T   + E  K + ++   R  E    RI  E +  I+Q + ++   + EF+ +IE   + 
Sbjct: 550  TLTKQYERLKKEGEMSFQRQSEKEKSRII-ELERQIIQLENQLSLQKKEFSLKIEEVNQS 608

Query: 943  K----------KVLNEKYEKNIEYVTQLEAQLQ-EYKNNIENLNMNVEELNKMNLELIDK 991
                       K +NEK ++    V QL  QL  E K  +++      E+  + L+  DK
Sbjct: 609  SNLKEYYEIQLKQINEKLQREQNQVKQLNEQLLIEQKKILDSETKYSREIRDIKLQQ-DK 667

Query: 992  HVQKQQ-TQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKL 1050
             ++ QQ TQ     E +  ++ KL    +  ++E   +  ++   +  +      ++  +
Sbjct: 668  RIEIQQNTQFQFEWENHQKDMEKLRREYRLIEQEYQEMEVQVKLWKEKFYDEQQKHQD-I 726

Query: 1051 AQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTE 1110
             Q   ++ +  E    V+ Q    KQ  +EL++ + +  +Q++     +  ++  I  T 
Sbjct: 727  RQQLIEIRSQYESHTIVNTQSDYDKQRYQELEMEIIQLQEQMRLFSIREEKYKEQIT-TY 785

Query: 1111 GMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQE 1170
             M I    +   DD   +             ++ ++ E  +Q++S+  E   KL  + QE
Sbjct: 786  SMTIEKQ-KSNFDDLKKIKHLEYEIESQR--IQYRDLERQLQDKSIEYE---KLLKKKQE 839

Query: 1171 CYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLL-STVAE---LRSSISS 1226
               + I++ + + +L   ++ +Q QI  L+ +L+QLN+    ++  T+ E   +RSS   
Sbjct: 840  VKLETIEISSNSDKLKIQELESQIQI--LRLQLQQLNSSKQEVIRETIRETVQVRSSEDI 897

Query: 1227 AVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLD-SVQSSTQEETNK 1285
             +  +  E  +LWK    + +    +   E   ++ + ES  +++ +   Q  +     +
Sbjct: 898  KMIAQLEEELQLWKTKYYELDRRKNQVVVETIREVQSLESDKQRIQELEYQLQSLSSKKQ 957

Query: 1286 IVTMEQVT-SLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXX 1344
             V  E +T +++  L+  +  +R L+ + +++    ++L S+ + E +            
Sbjct: 958  EVIREYITETIEVPLESDKLKIRQLETQLSNIQRDYQLL-SQKKQEVIQETITVEVPNQA 1016

Query: 1345 XXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLE 1404
                   L  E+Q  +  QE  ++++ ++    +  +            R+N  + ++  
Sbjct: 1017 DKYRIQQL--ESQLSQVRQELQVVSLKKQEVIKEIVTERIEVPMEQDRLRINHLQEQLSR 1074

Query: 1405 LTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRL 1464
            L    ++ D +  Q+  + TIT+ + + + + +R Q      ++E    E +++L ++  
Sbjct: 1075 LQRDYQILDQK-KQEVIKETITV-EVSSQADKLRIQ------QLESQLSELKTQLQLIIQ 1126

Query: 1465 KMHENANHYETMQKESEIERVKL-IEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQ 1523
            K  E      T + E   E  K  I +L  +I     LNK    LNK  +E + +   ++
Sbjct: 1127 KKQEVIREIITERVEVSSEADKFRIRQLEQQIE---GLNKNYEILNKRKQEVITERITVE 1183

Query: 1524 TALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDA 1583
               +  +++I  L   +T L+  ++  SS+ Q+ +      +     Q+D    ++L   
Sbjct: 1184 VPSQADKLKIQQLETLLTQLRQELQIVSSRKQEVIKEVVTERVEVPSQVDKLRIQQLEQQ 1243

Query: 1584 VPRAELDLAMYMLHQRDV 1601
            +     +L +    ++++
Sbjct: 1244 LDNVRYELQILSQKKQEI 1261



 Score =  130 bits (314), Expect = 3e-28
 Identities = 277/1473 (18%), Positives = 612/1473 (41%), Gaps = 149/1473 (10%)

Query: 212  EDTKQQMTKMQENFIAMEAE-WKDEKQRL---LKDIESKDVRISSLEEANKLLEAARFEI 267
            ++ K Q    Q + I  E E WK +   L   +KD ++  +++  LEE +   +    ++
Sbjct: 329  QNDKVQRESYQIHTIQNELESWKQKYISLEIKMKDYDNYRMQLIQLEEQSNFYKNENDQM 388

Query: 268  SLEHSKLAQELEQXXXXXXXXXXXXXXL---AKQSIEPSCEEKTEIEE-KGSLEIANMTE 323
              E   L  E++Q              L   A+ S+E     K++I   + ++   N   
Sbjct: 389  KEELEILIAEIKQLQEQNNGYRLSITQLESQARNSVEND-RYKSQIRNLENTINQLNQQI 447

Query: 324  LTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLIS--RKSGRNTASK 381
               KIE  E     I   NK   N    +  + + +S    K + +    R         
Sbjct: 448  NAYKIETKELEQQVIYHQNKNT-NVDYQVREKEETISKLQYKLNNMEKELRVIFEEQLKI 506

Query: 382  MKSPWSQLSSETLNQDTDKKINK--NEIAKLEMVIQSLN--KDLVDKEYVISEKDTXXXX 437
             K  W +   + ++    K   K  +EI+ L     SL      + K+Y   +K+     
Sbjct: 507  EKQDWDRQKQQQIDDQLQKITKKYESEISTLRQHFSSLEIENQTLTKQYERLKKEGEMSF 566

Query: 438  XXXXXXGKDTLIAQ----LQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEI 493
                   K  +I      +QLE+Q  ++           E+VN+ + ++E          
Sbjct: 567  QRQSEKEKSRIIELERQIIQLENQLSLQKKEF---SLKIEEVNQSSNLKEYY-------- 615

Query: 494  KDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDS 553
             ++ +K + EKL+  + Q+ QLN+++    K ++  ++ +  +++ ++   D   ++  +
Sbjct: 616  -EIQLKQINEKLQREQNQVKQLNEQLLIEQKKILDSETKYSREIRDIKLQQDKRIEIQQN 674

Query: 554  NK---EIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAE 610
             +   E     +++  L ++   +E+E   +++ +      ++ +   Y +  + +++ +
Sbjct: 675  TQFQFEWENHQKDMEKLRREYRLIEQEYQEMEVQV------KLWKEKFYDEQQKHQDIRQ 728

Query: 611  TRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDA 670
              ++  S  ES      Q  +  +Q+Y E+E    +I QLQ       I+    +EQI  
Sbjct: 729  QLIEIRSQYESHTIVNTQSDYD-KQRYQELE---MEIIQLQEQMRLFSIREEKYKEQITT 784

Query: 671  LSAS-------------KKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQEN 717
             S +              K L   IE+ ++    L   ++D   + E ++ K Q    E 
Sbjct: 785  YSMTIEKQKSNFDDLKKIKHLEYEIESQRIQYRDLERQLQDKSIEYEKLLKKKQEVKLET 844

Query: 718  MDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQE--RDLYIENIESELSKYK 775
            ++++   +K+   KI EL ++I   +  ++Q Q  +++  QE  R+   E ++   S+  
Sbjct: 845  IEISSNSDKL---KIQELESQI---QILRLQLQ-QLNSSKQEVIRETIRETVQVRSSEDI 897

Query: 776  SRICRLEESIAVMEDRRYSLERKADQ-LGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHD 834
              I +LEE + + + + Y L+R+ +Q +   ++E Q   S+   +  EL  +L  L    
Sbjct: 898  KMIAQLEEELQLWKTKYYELDRRKNQVVVETIREVQSLESDKQ-RIQELEYQLQSLSSKK 956

Query: 835  RVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEK----ANRTDLAE 890
            + V ++ +    E  E+  ++  L  + + L+  LS++Q+ Y  L +K       T   E
Sbjct: 957  QEVIREYIT---ETIEVPLESDKL--KIRQLETQLSNIQRDYQLLSQKKQEVIQETITVE 1011

Query: 891  SESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIE---------------FNTQ 935
              +   + +++ LES L ++  E Q + ++K++ I+++  E                  Q
Sbjct: 1012 VPNQADKYRIQQLESQLSQVRQELQVVSLKKQEVIKEIVTERIEVPMEQDRLRINHLQEQ 1071

Query: 936  IESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQK 995
            +    RD ++L++K ++ I+    +E   Q  K  I+ L   + EL K  L+LI   +QK
Sbjct: 1072 LSRLQRDYQILDQKKQEVIKETITVEVSSQADKLRIQQLESQLSEL-KTQLQLI---IQK 1127

Query: 996  QQTQSPDYTEQYINEINKLNAL-LKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFT 1054
            +Q    +   + +   ++ +   ++Q +++I  LN+           ++++      + T
Sbjct: 1128 KQEVIREIITERVEVSSEADKFRIRQLEQQIEGLNKNYEILNKRKQEVITE------RIT 1181

Query: 1055 TKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMII 1114
             ++ +  ++++    + L   Q  +ELQI+   + + IKE+   ++     + K     +
Sbjct: 1182 VEVPSQADKLKIQQLETL-LTQLRQELQIVSSRKQEVIKEVVTERVEVPSQVDKLRIQQL 1240

Query: 1115 SSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSV-LQEQSAKLNTE---LQE 1170
               ++ +  +   +              +V+   E  ++R + L+    KL  +   L +
Sbjct: 1241 EQQLDNVRYELQILSQKKQEIIREVVTERVEVSRESDRKRILELESDLYKLQQDFINLNK 1300

Query: 1171 CYTKIIQLETLNTELTGH-DVVN----QEQINQLKSKLEQLNTENDNLLSTVAELRSSIS 1225
              +++++ ET+  E+    D       + Q++Q++S+L+ ++ +  +++      R  +S
Sbjct: 1301 IKSEVVK-ETVTVEVPSQADKFRIQQLETQLSQVRSELQIVSAKKQDVIRETVTERIEVS 1359

Query: 1226 SAVD-----QRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYE-QLLDSVQSST 1279
            S  D     Q   ++  L + +    +   +K +  L V++ +   +Y  + L+S  SS 
Sbjct: 1360 SEQDKMRIRQLEQQLNSLQQDYFTLNQKKQEKIKETLTVEVPSETDRYRIRQLESQLSSL 1419

Query: 1280 QEETNKIVTMEQVTSLQNK-LQ----DKEEHLRNLQEKYAD------VINQIEILRSEIE 1328
            +E+ N I    Q   +QNK LQ    + ++ +R  Q K  +      ++ Q E    E+ 
Sbjct: 1420 KEDYNGIQVENQNLKIQNKSLQTTNYEYQDQVRIFQSKLEENSKQRSIVIQFERKEQELL 1479

Query: 1329 DEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKK-----SSXX 1383
            ++  +                  L+ ENQ    M    +    EE+ Q K+      S  
Sbjct: 1480 EQIQSLEAQKVREIKELKIQIEFLQKENQKINDMMRIKV----EESEQWKRKYQTVQSEM 1535

Query: 1384 XXXXXXXXXXRVNDAEAKVLELTHQLEL-KDSEIY-QKTHEYTITLTQRND---EFENVR 1438
                      R+     +    T +LEL K +++Y Q  +EYT   ++ N+     + + 
Sbjct: 1536 SSNSSESESLRMQLKSLEQSRETIKLELDKVNKMYFQSQNEYTQYKSKCNELELRIKQIS 1595

Query: 1439 QQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITES 1498
            ++  EY++R + + +EK S L     +  E     E +Q  +++    L  +++ K  + 
Sbjct: 1596 RENQEYQERYQQIDFEKISRLEQENRRKTETIQQLE-VQLRNQVSIKDLQSQISNKDKQI 1654

Query: 1499 VSLNKQVAELNKALEEEVAKTNEMQTALENQEIEI--VTLNDEITNLQNMVRASSSKIQK 1556
              L + ++EL   +     +   +      Q++ +     N +I  L+  ++  + +IQ+
Sbjct: 1655 FQLQENISELQGTIRSLRVENQTISEQTNKQQVIVRETQNNQKIVELETRIQGLNQEIQR 1714

Query: 1557 HVSFASDTKQGRDEQLDNTMNKELLDAVPRAEL 1589
             +      +   D+ ++     E    + R EL
Sbjct: 1715 QIQMKDQIQIKHDKLIERATEYESEINILRNEL 1747



 Score = 72.1 bits (169), Expect = 1e-10
 Identities = 115/650 (17%), Positives = 263/650 (40%), Gaps = 40/650 (6%)

Query: 948  EKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQY 1007
            EKY+     V   + ++ +  NN+      + E  +    L D    K+  +  D   Q 
Sbjct: 20   EKYQTTSGIVASTDKRIVD--NNLSGRKSTLFEDKRYEELLQDNRKLKEVIEQLDKDNQQ 77

Query: 1008 INEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRV 1067
            + +++  +  LKQK     A  +          S +    S+ A+ +T +   ++++  +
Sbjct: 78   LKQMSGESYNLKQKYMIAQAELEAAQQELAKLRSQLLMRNSQDAEQSTLVTRYKQDVSTL 137

Query: 1068 SKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPM------ 1121
            ++Q +  +Q   +L  L+ +Q  Q++E    K  +E ++        +  IE        
Sbjct: 138  TQQQIQYQQEISQLNALLEQQRKQVEEFLRLKSKYEQDVQTYRSRAQNLEIEIRQVKEQR 197

Query: 1122 -SDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSV--LQEQSAKLNTELQECYTKIIQL 1178
             S   N +             ++V+  ++ + ER++  L ++  +++ ++Q       Q 
Sbjct: 198  NSTTQNEIIRLTQEIARYQSEVQVRSSDKELYERTISTLNDKIKEMDNDIQILIEAQNQN 257

Query: 1179 E-TLNTELTGHDVVNQEQINQLKSKLEQLNTEN---DNLLSTVAELRSSISSAVDQRGFE 1234
            +  L + +       Q QI+QLK ++    T+         TV   +      + Q    
Sbjct: 258  QYKLESAMAESKSNMQYQIDQLKQEMTFYQTQCKQWQEKCQTVEMQKEESERRIIQMEIR 317

Query: 1235 IAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTS 1294
            I E  KQ   Q+    Q+  +++    +  ES ++Q   S++   ++  N  + + Q+  
Sbjct: 318  INETKKQIEQQQNDKVQRESYQIHTIQNELES-WKQKYISLEIKMKDYDNYRMQLIQLEE 376

Query: 1295 LQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXX--XDL 1352
              N  +++ + ++   E+   +I +I+ L+ +    +++                    +
Sbjct: 377  QSNFYKNENDQMK---EELEILIAEIKQLQEQNNGYRLSITQLESQARNSVENDRYKSQI 433

Query: 1353 RTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELK 1412
            R    +  Q+ +Q I     E  +L++              +V + E  + +L ++L   
Sbjct: 434  RNLENTINQLNQQ-INAYKIETKELEQQVIYHQNKNTNVDYQVREKEETISKLQYKLNNM 492

Query: 1413 DSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMH----E 1468
            + E+     E    L     +++  +QQ ++   +++ +T + ESE++ LR        E
Sbjct: 493  EKELRVIFEEQ---LKIEKQDWDRQKQQQID--DQLQKITKKYESEISTLRQHFSSLEIE 547

Query: 1469 N---ANHYETMQKESEIERVKLIEELNVKITES----VSLNKQVAELNKALEEEVAKTNE 1521
            N      YE ++KE E+   +  E+   +I E     + L  Q++   K    ++ + N+
Sbjct: 548  NQTLTKQYERLKKEGEMSFQRQSEKEKSRIIELERQIIQLENQLSLQKKEFSLKIEEVNQ 607

Query: 1522 MQTALENQEIEIVTLNDEITNLQNMVRASSSK--IQKHVSFASDTKQGRD 1569
                 E  EI++  +N+++   QN V+  + +  I++     S+TK  R+
Sbjct: 608  SSNLKEYYEIQLKQINEKLQREQNQVKQLNEQLLIEQKKILDSETKYSRE 657


>UniRef50_A0BTE2 Cluster: Chromosome undetermined scaffold_127, whole
            genome shotgun sequence; n=3; Paramecium tetraurelia|Rep:
            Chromosome undetermined scaffold_127, whole genome
            shotgun sequence - Paramecium tetraurelia
          Length = 1858

 Score =  130 bits (313), Expect = 4e-28
 Identities = 280/1367 (20%), Positives = 594/1367 (43%), Gaps = 152/1367 (11%)

Query: 218  MTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHS---KL 274
            M  +  N  A+E E   E  R+ KD   K++   + ++  K +E  R EISL+ S   KL
Sbjct: 1    MQSLAGNKEAIEKELSLE--RVAKDGLKKEILQITNQQKIKDMEL-RNEISLKSSEIIKL 57

Query: 275  AQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHL 334
             +E E+              + +Q+ +    +  +++EK  LEI+      K+IE+   L
Sbjct: 58   NKEAERLDGLFKQATLELKRINEQNEDLRLIDDFQLKEK-DLEISKF----KQIEI--EL 110

Query: 335  NCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETL 394
              +I+Q  K+L N+   +  E+  +    K  +  +S  + R    K ++       + L
Sbjct: 111  KNRIQQLQKQLSNQEWQLSQENIKLKQQVKDLNNDVSILNTRVNMLKTQNKDESERFQEL 170

Query: 395  NQDTDKKINK--NEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQL 452
             Q  D ++    +        I+++ + L   +     K+             D L  Q 
Sbjct: 171  LQSHDVELQSWADRYKDQSQQIETMAQQLFAAQQQNKYKEQLIFEYDKLKQEFDLLNRQY 230

Query: 453  QLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVN-VKDLIEKLKSAEEQ 511
            Q   +  +   +   +  N ++V E+ ++QE  +Q++    K+++ ++D    L+  +  
Sbjct: 231  QSLQENSLRNSN---IKENAKNV-EMQQLQEHYEQQVVQLQKEIDFMRDNKVNLRQ-DAS 285

Query: 512  ITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKV 571
            +   + +I A N  +  VK N+++   +MQ        + + + +I+ L E+L  L  KV
Sbjct: 286  VIDFSVQITALNDQL--VKKNNEITNIRMQAN----RTIMEKDNQIILLQEQLEQLISKV 339

Query: 572  AELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELH 631
              +E  + +    +   ++  +I ++  K +++++       + +   + Q  ++ ++L 
Sbjct: 340  DIIENNQNDQAEAIEKAENLELIMNEKDKFIVQLK-------EELQNCKDQILEMEEQLK 392

Query: 632  ILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQ 691
            I Q   D ++ + + IS+L+S     +++   +E Q       K       ++++    +
Sbjct: 393  IRQNSLDMIQQQASLISELKS-----QVERRQIENQTGV--QPKPVQQCFTKSIRSSTHR 445

Query: 692  LYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQF 751
            + G  K  +N +E    ++ +Y+Q+  D++ K ++ + + IS +  +I+  +Q   Q+Q 
Sbjct: 446  MSG--KKSQNIEES-QKEIISYVQKVTDVSFK-QQSNQQIISIVNPQISETKQILRQSQ- 500

Query: 752  GIDAKIQERDLYIENI---ESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQE 808
                ++Q+R+L  ++I   + EL + K  +   +++ + +         K +QL    Q 
Sbjct: 501  ---EELQQRNLLNQSIMVLQQELKQVKLNLSNEQQASSQLRFELSQANAKIEQL----QL 553

Query: 809  KQKAYSEYTIQEDEL-VNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQI 867
            +Q      + Q D + V+RL  +                  K  +   Q L  E Q+LQ 
Sbjct: 554  EQSQLKNKSQQNDSINVDRLNTM----------------SMKTYESNMQSLKSEKQDLQQ 597

Query: 868  SLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIED 927
             L + +Q +     + N     ++E  K + Q++ L  +     ++ +  I + K  I+ 
Sbjct: 598  KLIEQEQQFTTFTSRINEL---QNEIKKQKEQIQQLNDS----ENQKENQIFEYKSIIDR 650

Query: 928  LEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQ-LEAQLQEYKNNIENLNMNVEELNKMNL 986
            L+    ++ +S +R K+   ++     E + Q L+ + QE K N   L+       K+ L
Sbjct: 651  LQNNLKSE-QSIVRQKQSEVKQITYQQEQIQQMLQQEYQEIKKNNNELSQQ-----KLKL 704

Query: 987  ELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDY 1046
            EL  + ++ Q  QS    + Y ++I KLN+ +    E++    QK    + +      + 
Sbjct: 705  ELEIQELKSQLQQSQVNQQFYESKITKLNSEILLVREKLGKFEQKTIQIEQTKTQSSQNS 764

Query: 1047 ESKLAQFTTKLENMEEEMQRVSKQL--LDSKQHNEELQILVREQDDQIKELKETKLTFEM 1104
            +   +QF  +++ +  +++R  +QL  L+ ++ N +LQIL  +  D I + + +    + 
Sbjct: 765  DQLQSQFQQQIQELTSKLER-QQQLSNLNQQELNNQLQILKEQYQDTIFKFENS----QE 819

Query: 1105 NIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKL 1164
             +   +  +     + ++D   N              LK+Q  E   Q+ S  +E     
Sbjct: 820  QVKLLQNSLAQQKQQYLNDMNENAQ-MLSITNQENQNLKIQ-IEHLNQQLSAYKES---- 873

Query: 1165 NTELQECYTKIIQLETLNTE--LTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAE--- 1219
            NT +Q+  +++ QL+    E  L   D+ NQ Q NQL  + +Q   E  +L+  + E   
Sbjct: 874  NTNVQKWQSQVDQLQKQLREDKLQQQDLNNQLQ-NQL-FQFQQSKREWQDLIQRLQEDNN 931

Query: 1220 -LRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFES--KYEQLLDSVQ 1276
             L+++++  +  R  +  E    +  Q+  + Q T + ++ Q  +  S    E++L  +Q
Sbjct: 932  QLQANLNRVLTARSEK--EQIDNYTHQQNQNIQITTNTIKTQFMSNTSGMSSEKILIELQ 989

Query: 1277 SSTQEETNKIVTMEQVTSLQNK-----LQDKEEHLRNLQEKYADVINQIEILR----SEI 1327
             + QEE  K+++  QV  L NK     +QD +E  R L+ +Y +   +I++       +I
Sbjct: 990  IA-QEENVKLISQLQVLQLNNKQLNKEIQDFDEKQRQLENRYKEQYLRIQLEHDLSFKKI 1048

Query: 1328 EDEKV-------AFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKS 1380
            E E V        +                 +   N    Q+Q Q +L + ++N+   K 
Sbjct: 1049 EQENVKLISQVEVYQKKQQQQEILIDDYIAQIEKLNIINNQLQSQLLL-VQKDNSNFYKD 1107

Query: 1381 SXXXXXXXXXXXXRV--NDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVR 1438
                         ++     +    + T QL++KD  + ++T E    L+Q ++E  ++ 
Sbjct: 1108 QDKQIYRLSEINQQLLTQITQLNNQKNTDQLQIKDLIVIKQTLEE--QLSQHSEEIFSLN 1165

Query: 1439 QQLVEYEKRIEDLTYEK----------ESELAILRLK----MHENANHYETMQ-KESEIE 1483
            ++L +   +   LT+            +++L+ L++K    ++EN   +   Q ++S   
Sbjct: 1166 ERLKDLSDQNTQLTHMNSGYLNQITGLQAQLSELQIKFTQNIYENKPRFSDQQPRQSTSS 1225

Query: 1484 RVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQE 1530
              + IEELN KI   +SLN QV  LN+   +   +   ++  L+N++
Sbjct: 1226 NSRQIEELNNKI---ISLNNQVNILNQQKSQIQQELISVRKQLQNEQ 1269



 Score =  129 bits (312), Expect = 5e-28
 Identities = 291/1476 (19%), Positives = 594/1476 (40%), Gaps = 136/1476 (9%)

Query: 161  LQVKMKIMETTILDLQEKI-NEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMT 219
            L++ M   +  I+ L+E++ N KDQI+E + +                     + K Q+ 
Sbjct: 359  LELIMNEKDKFIVQLKEELQNCKDQILEMEEQLKIRQNSLDMIQQQASLIS--ELKSQVE 416

Query: 220  KMQ-ENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQEL 278
            + Q EN   ++   K  +Q   K I S   R+S  +  N  +E ++ EI     K+    
Sbjct: 417  RRQIENQTGVQP--KPVQQCFTKSIRSSTHRMSGKKSQN--IEESQKEIISYVQKVTDVS 472

Query: 279  --EQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTK-KIELL--EH 333
              +Q                KQ +  S EE  +        +    EL + K+ L   + 
Sbjct: 473  FKQQSNQQIISIVNPQISETKQILRQSQEELQQRNLLNQSIMVLQQELKQVKLNLSNEQQ 532

Query: 334  LNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPL-------ISRKSGRNTASKMKSPW 386
             + Q+R    +   K+  +  E   + + S++   +       +S K+  +    +KS  
Sbjct: 533  ASSQLRFELSQANAKIEQLQLEQSQLKNKSQQNDSINVDRLNTMSMKTYESNMQSLKSEK 592

Query: 387  SQLSSETLNQDTD-----KKINK--NEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXX 439
              L  + + Q+        +IN+  NEI K +  IQ LN     KE  I E  +      
Sbjct: 593  QDLQQKLIEQEQQFTTFTSRINELQNEIKKQKEQIQQLNDSENQKENQIFEYKSIIDRLQ 652

Query: 440  XXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQE-LNDEIKDVNV 498
                 + +++ Q Q E +Q       I      E   EI K   +L Q+ L  E++   +
Sbjct: 653  NNLKSEQSIVRQKQSEVKQITYQQEQIQQMLQQE-YQEIKKNNNELSQQKLKLELEIQEL 711

Query: 499  KDLIEKLKSA----EEQITQLNDEIDAANKNMIKVKSNH-KLKLKQMQKTIDNFSKVSDS 553
            K  +++ +      E +IT+LN EI    + + K +    +++  + Q + ++    S  
Sbjct: 712  KSQLQQSQVNQQFYESKITKLNSEILLVREKLGKFEQKTIQIEQTKTQSSQNSDQLQSQF 771

Query: 554  NKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVD---YDSGRMIESDVYKKMIEMENLAE 610
             ++I  LT +L    Q+++ L +++ N QL ++     D+    E+   +  +   +LA+
Sbjct: 772  QQQIQELTSKLER-QQQLSNLNQQELNNQLQILKEQYQDTIFKFENSQEQVKLLQNSLAQ 830

Query: 611  TRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDA 670
             + + ++ +        Q L I  Q+   ++ ++  ++Q  S    S       + Q+D 
Sbjct: 831  QKQQYLNDMNEN----AQMLSITNQENQNLKIQIEHLNQQLSAYKESNTNVQKWQSQVDQ 886

Query: 671  LSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEK-MSA 729
            L    +E  L  ++L     QL   +   +  K +  + +Q   ++N  L   L + ++A
Sbjct: 887  LQKQLREDKLQQQDLN---NQLQNQLFQFQQSKREWQDLIQRLQEDNNQLQANLNRVLTA 943

Query: 730  EKISELLAKINHEEQSKIQ-TQFGIDAKIQERD--LYIENIESELSKYKSRICRLEESIA 786
                E +    H++   IQ T   I  +       +  E I  EL   +    +L   + 
Sbjct: 944  RSEKEQIDNYTHQQNQNIQITTNTIKTQFMSNTSGMSSEKILIELQIAQEENVKLISQLQ 1003

Query: 787  VMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEH 846
            V++     L ++        ++ +  Y E           L + ++HD   +K    IE 
Sbjct: 1004 VLQLNNKQLNKEIQDFDEKQRQLENRYKE---------QYLRIQLEHDLSFKK----IEQ 1050

Query: 847  ENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANR-TDLAESESTKYQTQ----LR 901
            EN +L  + ++  ++ Q  +I + D    Y A +EK N   +  +S+    Q       +
Sbjct: 1051 ENVKLISQVEVYQKKQQQQEILIDD----YIAQIEKLNIINNQLQSQLLLVQKDNSNFYK 1106

Query: 902  DLESNLKRITHEHQTLIVQKKKEIEDLEIEFNT---QIESAIRDKKVLNEKYEKNIEYVT 958
            D +  + R++  +Q L+ Q    I  L  + NT   QI+  I  K+ L E+  ++ E + 
Sbjct: 1107 DQDKQIYRLSEINQQLLTQ----ITQLNNQKNTDQLQIKDLIVIKQTLEEQLSQHSEEIF 1162

Query: 959  QLEAQLQEYKN-NIENLNMNVEELNKMN------LELIDKHVQKQQTQSPDYTEQYINEI 1011
             L  +L++  + N +  +MN   LN++        EL  K  Q      P +++Q   + 
Sbjct: 1163 SLNERLKDLSDQNTQLTHMNSGYLNQITGLQAQLSELQIKFTQNIYENKPRFSDQQPRQS 1222

Query: 1012 NKLNAL-LKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQ 1070
               N+  +++ + +II+LN ++N          S  + +L     +L+N +++  R S+Q
Sbjct: 1223 TSSNSRQIEELNNKIISLNNQVNILN----QQKSQIQQELISVRKQLQNEQDD--RFSQQ 1276

Query: 1071 LLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDX 1130
               S+Q+      +  E +++I++L++     ++        +     + M  + NN   
Sbjct: 1277 ---SRQNRSNQYKVASEMEERIRQLQQQLEEEKLGKFSNNSEVELKNKQIMILEQNN--- 1330

Query: 1131 XXXXXXXXXXXLKVQEEEEFI-QERSVLQEQSAK---LNTELQ--ECYTKIIQLETLNTE 1184
                       L+++EE+  + +E   L EQ+ +   L T     E    + Q E+L  E
Sbjct: 1331 KKLQQQLEQLNLQIEEEKSLLYKEIDQLSEQNKRTKQLKTSEYDIEFRNSVKQSESLKQE 1390

Query: 1185 LTGHDVVNQEQINQLKSKLEQLNTENDNLLST------VAELRSSISSAVDQRGFEIAEL 1238
            L   +   ++Q +++ +  +Q+  +N+  +        + EL   +     +   EI EL
Sbjct: 1391 LLQANQTIKKQQSRIATLEDQITKQNNGSIDMDRQNRFILELEEKLKGNQRKYEIEIKEL 1450

Query: 1239 WKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTS-LQN 1297
             K          +K ++EL+   S +  + E+    +Q   Q  + ++       S L+ 
Sbjct: 1451 -KNDKQSLNQQLEKAQYELQEIKSKYHIELEKTEQKLQKENQRFSLQLNDKAAYLSQLEV 1509

Query: 1298 KLQDKEEHLRNLQEKYADVINQI-EILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTEN 1356
            K +  +E + N QE+Y + + Q  E ++   ED ++                      +N
Sbjct: 1510 KNRQLKEEILNQQERYDEKLRQANERIKEVTEDLEIMIDNYKKEKQLSQKW-----ERQN 1564

Query: 1357 QSYKQMQEQSI--LNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDS 1414
            +  ++  + S+  + I  E   ++K                     ++  L   + LK+ 
Sbjct: 1565 EDLRRQLQSSVDDVKIKTERLSVEKYERMSLDSRKQIEQVQQQLNNEINGLKQDIRLKNE 1624

Query: 1415 EIYQKTHEYTITLTQRNDEFE----NVRQQLVEY----EKRIEDLTYEKESELA-ILRLK 1465
            +I Q       +L Q+  +FE    ++  QL ++    E+ + DL   K   LA  L +K
Sbjct: 1625 QINQ-LKSTNQSLQQKLSKFETYIRDLEDQLQQFSNKEEQLLRDLNQSKNQSLADSLNVK 1683

Query: 1466 MHENANHY-ETMQKESEI-ERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQ 1523
            +    N+  +  Q+E ++ ++++ +E        +        + N   EE       + 
Sbjct: 1684 VMALENNLVKAQQREDQLLQKIRQLENQQNSFRNNSDYRNLEVKNNNMFEE----IQILV 1739

Query: 1524 TALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVS 1559
              ++NQ+ EI TL +E+T+ Q  V      +++  S
Sbjct: 1740 QTIKNQDQEIATLKNELTSYQREVSFMKEVVKEDTS 1775



 Score =  124 bits (298), Expect = 3e-26
 Identities = 244/1100 (22%), Positives = 477/1100 (43%), Gaps = 118/1100 (10%)

Query: 176  QEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQ-MTKMQENFIAMEAEWKD 234
            Q+++N + QI++ + + T                     KQQ +  M EN   M +    
Sbjct: 793  QQELNNQLQILKEQYQDTIFKFENSQEQVKLLQNSLAQQKQQYLNDMNEN-AQMLSITNQ 851

Query: 235  EKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXX 294
            E Q L   IE  + ++S+ +E+N  ++  + ++     +L ++  Q              
Sbjct: 852  ENQNLKIQIEHLNQQLSAYKESNTNVQKWQSQVDQLQKQLREDKLQQQDLNNQLQNQLFQ 911

Query: 295  LAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGT 354
              +   E     +   E+   L+ AN+  +       E ++    Q N+ ++    T+ T
Sbjct: 912  FQQSKREWQDLIQRLQEDNNQLQ-ANLNRVLTARSEKEQIDNYTHQQNQNIQITTNTIKT 970

Query: 355  ESKAVSSPSKKGSPLISRKSGRNTASKMKSPWS--QLSSETLN---QDTDKKINKNEIAK 409
            +  + +S       LI  +  +    K+ S     QL+++ LN   QD D+K  + E   
Sbjct: 971  QFMSNTSGMSSEKILIELQIAQEENVKLISQLQVLQLNNKQLNKEIQDFDEKQRQLENRY 1030

Query: 410  LEMVIQ-SLNKDL----VDKEYV--ISEKDTXXXXXXXXXXGKDTLIAQLQLEH--QQHM 460
             E  ++  L  DL    +++E V  IS+ +             D  IAQ++  +     +
Sbjct: 1031 KEQYLRIQLEHDLSFKKIEQENVKLISQVEVYQKKQQQQEILIDDYIAQIEKLNIINNQL 1090

Query: 461  EGPSLIHVGTNT-------EDVNEIAKVQEQLKQEL----NDEIKD-VNVKDLIEKLKSA 508
            +   L+    N+       + +  ++++ +QL  ++    N +  D + +KDLI   ++ 
Sbjct: 1091 QSQLLLVQKDNSNFYKDQDKQIYRLSEINQQLLTQITQLNNQKNTDQLQIKDLIVIKQTL 1150

Query: 509  EEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLS 568
            EEQ++Q ++EI + N+ + K  S+   +L  M     N   ++       +L+E     +
Sbjct: 1151 EEQLSQHSEEIFSLNERL-KDLSDQNTQLTHM-----NSGYLNQITGLQAQLSELQIKFT 1204

Query: 569  QKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQ 628
            Q + E +    + Q       + R IE ++  K+I + N        +++L  QK  + Q
Sbjct: 1205 QNIYENKPRFSDQQPRQSTSSNSRQIE-ELNNKIISLNN-------QVNILNQQKSQIQQ 1256

Query: 629  EL-HILQQKYDEVEDKLADIS-QLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLK 686
            EL  + +Q  +E +D+ +  S Q +S+Q   ++ S  +EE+I  L    +E  L   +  
Sbjct: 1257 ELISVRKQLQNEQDDRFSQQSRQNRSNQY--KVAS-EMEERIRQLQQQLEEEKLGKFSNN 1313

Query: 687  LDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAE--KISELLAKINHEEQ 744
             + E     I  LE + + +  +L+   Q N+ + ++   +  E  ++SE   +    + 
Sbjct: 1314 SEVELKNKQIMILEQNNKKLQQQLE---QLNLQIEEEKSLLYKEIDQLSEQNKRTKQLKT 1370

Query: 745  SKIQTQFGIDAKIQERDLYIENIESE--LSKYKSRICRLEESIAVMEDRRYSLERKADQL 802
            S+   +F    K Q   L  E +++   + K +SRI  LE+ I    +    ++R+ ++ 
Sbjct: 1371 SEYDIEFRNSVK-QSESLKQELLQANQTIKKQQSRIATLEDQITKQNNGSIDMDRQ-NRF 1428

Query: 803  GSYLQEKQKAYS-EYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHE-NKELQKKNQILLE 860
               L+EK K    +Y I+  EL N    L       + +L EI+ + + EL+K  Q L +
Sbjct: 1429 ILELEEKLKGNQRKYEIEIKELKNDKQSLNQQLEKAQYELQEIKSKYHIELEKTEQKLQK 1488

Query: 861  ENQNLQISLSDMQQHYNALVEKANRTDLAE--SESTKYQTQLRDLESNLKRITHEHQTLI 918
            ENQ   + L+D   + + L E  NR    E  ++  +Y  +LR     +K +T + + +I
Sbjct: 1489 ENQRFSLQLNDKAAYLSQL-EVKNRQLKEEILNQQERYDEKLRQANERIKEVTEDLEIMI 1547

Query: 919  VQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEK-NIEYVTQLEAQLQEYKNNIENLNMN 977
               KKE                   K L++K+E+ N +   QL++ + + K   E L+  
Sbjct: 1548 DNYKKE-------------------KQLSQKWERQNEDLRRQLQSSVDDVKIKTERLS-- 1586

Query: 978  VEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIAL---NQKINN 1034
            VE+  +M+L   D   Q +Q Q     +Q  NEIN L   ++ K+E+I  L   NQ +  
Sbjct: 1587 VEKYERMSL---DSRKQIEQVQ-----QQLNNEINGLKQDIRLKNEQINQLKSTNQSLQQ 1638

Query: 1035 AQVSYMSMVSDYESKLAQFTTKLENMEEEM-QRVSKQLLDSKQHN----EELQILVREQD 1089
                + + + D E +L QF+ K E +  ++ Q  ++ L DS        E   +  ++++
Sbjct: 1639 KLSKFETYIRDLEDQLQQFSNKEEQLLRDLNQSKNQSLADSLNVKVMALENNLVKAQQRE 1698

Query: 1090 DQ----IKELKETKLTFEMNIP----KTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXX 1141
            DQ    I++L+  + +F  N      + +   +   I+ +     N D            
Sbjct: 1699 DQLLQKIRQLENQQNSFRNNSDYRNLEVKNNNMFEEIQILVQTIKNQDQEIATLKNELT- 1757

Query: 1142 LKVQEEEEFIQERSVLQEQSAKLNTE--LQECYTKIIQLET----LNTELTGHDVVNQEQ 1195
               Q E  F++E  V++E +++L T   L +   +I++LE     L  E T  + +  +Q
Sbjct: 1758 -SYQREVSFMKE--VVKEDTSRLETSSVLDDKNRRIVELENKCALLANENTRLNQLKVKQ 1814

Query: 1196 INQLKSKLEQLNTENDNLLS 1215
            +++ K K ++L  E +  L+
Sbjct: 1815 VDEWKVKYDKLQQELEKSLN 1834


>UniRef50_Q7RIN9 Cluster: Putative uncharacterized protein PY03578;
            n=8; Plasmodium (Vinckeia)|Rep: Putative uncharacterized
            protein PY03578 - Plasmodium yoelii yoelii
          Length = 1527

 Score =  129 bits (312), Expect = 5e-28
 Identities = 251/1236 (20%), Positives = 536/1236 (43%), Gaps = 129/1236 (10%)

Query: 89   GISESLANTLKQ-KEILMEKIKQYKELS----KRSSTTIVRXXXXXXXXXXXXXXXQLGD 143
            G+ E+L N  K+ K I M+  +    +S    KR+STT+VR               ++  
Sbjct: 347  GVIENLENKNKEIKRISMDNFEFNNPISNHINKRNSTTVVRSVFNPQLEYNNVENNEIRK 406

Query: 144  VTHLSNTIKEKDNALSVLQVKMKIMET-TILDLQEKINEKDQIIEAK---NKATTXXXXX 199
               + N          +L +  K++E     +  +  NE   I   K   +K T+     
Sbjct: 407  FNTIGNNYMNIGRENDILNISPKVIEKINRRNTHQLFNESSNISTDKLTIHKVTSPFLFD 466

Query: 200  XXXXXXXXXXXXE----DTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEE 255
                        E      K +  +  E    ME   K EK    + +E  +  ++S   
Sbjct: 467  NINNDSNTNVSNEIPEKGGKMEKVEKMEKMEKMEKMEKVEKMEEFEKMEKSNEHVNSFSM 526

Query: 256  ANK----LLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIE 311
             N      +E+    I+++ + +                    L  Q+I    + K + +
Sbjct: 527  FNLDKGVSVESTSNIIAMDENPIILNDSNTINKNNIIDAESDKLV-QNILDMIKIKLQDD 585

Query: 312  EKGSLE--IAN--------MTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSS 361
             K +++  I N        + E T  +E+L +  CQ+++ N+++E+K  T+  E+  ++ 
Sbjct: 586  NKNNIDTIIKNESKRITSLLEEKTGSMEILCNKICQLKKKNEDVEDKNDTIREETHQINI 645

Query: 362  PSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDL 421
               K + + +     N  +K      +  + + N     K+  +EI  +    +++    
Sbjct: 646  DKDKENEINNLLYVINIKNKKIKEELEAFTNSFNVLKKLKMKNDEIINIYKNRENVFLTT 705

Query: 422  VDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKV 481
            ++K   + EK             K+    +L ++ ++ ++    I    N +++ E  K 
Sbjct: 706  INK---LEEK---RKLKYAEFKEKEKQYKELIMKKEELLK----IXQINNKKNI-ETFKN 754

Query: 482  QEQLKQELNDEIK--DVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQ 539
            QEQ+   L DEI+  ++  K+ IE+LK   E+  ++N E     K    + +N + ++ +
Sbjct: 755  QEQM---LKDEIQKIELKTKEKIEELKQDFEKTQKINMENLEMEKESF-INNNLENEINK 810

Query: 540  MQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVY 599
            M++ ++   K     KE      E+ +  Q   E+E+ K N +    +++S    + + Y
Sbjct: 811  MKEKLE--EKYETQIKE-----TEMKYKYQIKEEIEKTKQNAE---QNFNS----KFEKY 856

Query: 600  KKMIEMEN---LAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVC 656
            K+ +E      +    ++  + +ES K D+ Q+     +K+ E  +KL     LQ++   
Sbjct: 857  KENLEKNKNDFINNLIIEKNNEIESFKNDIEQKKFKEMEKFKEENEKL-----LQNN--F 909

Query: 657  SEIKSVHLEEQIDALSASKKELALVIEN-LKLDKEQL-YGTIKDLENDKEDIMNKLQNYI 714
              +K+  +EEQ   +   KKE  L+  N ++  KE++    I+++EN +  + ++   +I
Sbjct: 910  ENMKNHFIEEQNKHIENIKKEYELIKNNEIEYLKEEMKKNKIQEIENVELKLADEKNKHI 969

Query: 715  QENMDLTDKLEKMSAEKISELLAKINHEE---QSKIQTQFGIDAKIQERDLYIENIESEL 771
                D+  +LE +   +I+ L  KIN E+   Q  ++TQ         R+ Y + +E + 
Sbjct: 970  D---DMKKELENIYNVEINNLKEKINAEQTLAQEMLETQ---------RNEYEQKLEIQR 1017

Query: 772  SKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLM 831
            ++Y+    +LE     ME++     +++  LGS      K  SE  I  D+ + +L + +
Sbjct: 1018 NEYEQ---QLEIRRNEMENKLIEQRKESYDLGS------KKESEIQILTDK-IEKLKMEI 1067

Query: 832  DHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAES 891
            +   ++ K+ +++EH    L  + + +L +N+NL+ +L + +  YN       + ++   
Sbjct: 1068 E---IINKEKIDLEHNISILNDERENILNQNKNLEDNLKNNEDIYN------KKINILND 1118

Query: 892  ESTKYQTQLRDLESN-LKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKY 950
            E  K + ++  ++ N  K      +      ++EI+ ++ E   ++   I+    +NE+Y
Sbjct: 1119 EKLKLEKEIEHIKENGAKESDQIREQFADLLQEEIDRIKKESKEKVNIYIQQYNEINEEY 1178

Query: 951  -EKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMN--LELIDKHVQ-----KQQTQSPD 1002
             EK  EY   LE      K   E    N++++N+    +++++   +     K Q  + D
Sbjct: 1179 EEKKKEYNDLLEKANVSNKQLTEKCEENIQKINEYEDMIKMLENQTEVLVTKKIQELNED 1238

Query: 1003 YTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEE 1062
            + ++     N+ N LLK   E  I  N+ I     ++    +  E K++Q   + E   +
Sbjct: 1239 FLKKKEAFDNEKNDLLKNY-EHAITENKHIKEQLENF---TNSNEEKISQIKNQYETQIK 1294

Query: 1063 EMQRVSKQLLD--SKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEP 1120
            EMQ    +LL+    ++NE L+ +V+EQ+D+ + ++         + K E + ++  I  
Sbjct: 1295 EMQIHFDELLNETKNKNNEMLEDIVKEQNDKEQSIQHMNSVNTELVTKNEQLNLN--ITE 1352

Query: 1121 MSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLN--TELQ-ECYTKIIQ 1177
            + ++ +N              LK +E+ +F+ +   L+  +  L   TE + E   K + 
Sbjct: 1353 IKNELSNFQEKYDKLVKENNHLKNEEQTKFLDKILDLENVNKHLMEVTEKEREINIKNVN 1412

Query: 1178 -LETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLL--STVAELRSSISSAVDQRGFE 1234
             +++L  ++     + +E  ++LK ++ QL  +  N +  +   +  SSI++A+ +   +
Sbjct: 1413 IIKSLQNQINEQTKLYKEYTDELKDEILQLKKQKKNSIDSNVPIDANSSINNALIEENKK 1472

Query: 1235 IAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQ 1270
            + +L  + ++ +          L  +LS  ESK ++
Sbjct: 1473 L-KLQNEVISTKNDTMSTVLDNLTKRLSFIESKIKE 1507



 Score =  109 bits (263), Expect = 5e-22
 Identities = 202/1037 (19%), Positives = 453/1037 (43%), Gaps = 83/1037 (8%)

Query: 315  SLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPL-ISRK 373
            S EI       +K+E +E +    +    E   +   M   ++ V+S S       +S +
Sbjct: 477  SNEIPEKGGKMEKVEKMEKMEKMEKMEKVEKMEEFEKMEKSNEHVNSFSMFNLDKGVSVE 536

Query: 374  SGRNTASKMKSPWSQLSSETLNQDT-----DKKINKNEIAKLEMVIQSLNKDLVDKEYVI 428
            S  N  +  ++P     S T+N++        K+ +N +  +++ +Q  NK+ +D   +I
Sbjct: 537  STSNIIAMDENPIILNDSNTINKNNIIDAESDKLVQNILDMIKIKLQDDNKNNIDT--II 594

Query: 429  SEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQE 488
              +            G   ++     + ++  E     +  T  E+ ++I  + +  + E
Sbjct: 595  KNESKRITSLLEEKTGSMEILCNKICQLKKKNEDVEDKN-DTIREETHQI-NIDKDKENE 652

Query: 489  LND-----EIKDVNVKDLIEKLKSAEEQITQL---NDEIDAANKNMIKVKSNHKLKLKQM 540
            +N+      IK+  +K+ +E   ++   + +L   NDEI    KN   V      KL++ 
Sbjct: 653  INNLLYVINIKNKKIKEELEAFTNSFNVLKKLKMKNDEIINIYKNRENVFLTTINKLEEK 712

Query: 541  QKT-IDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVY 599
            +K     F +     KE++   EEL  + Q   +   E    Q  ++  D  + IE    
Sbjct: 713  RKLKYAEFKEKEKQYKELIMKKEELLKIXQINNKKNIETFKNQEQMLK-DEIQKIELKTK 771

Query: 600  KKMIEM-ENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSE 658
            +K+ E+ ++  +T+   +  LE +K   +   + L+ + +++++KL +  + Q  +   +
Sbjct: 772  EKIEELKQDFEKTQKINMENLEMEKESFIN--NNLENEINKMKEKLEEKYETQIKETEMK 829

Query: 659  IKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENM 718
             K   ++E+I+      K+ A    N K +K +     ++LE +K D +N L   I++N 
Sbjct: 830  YK-YQIKEEIE----KTKQNAEQNFNSKFEKYK-----ENLEKNKNDFINNL--IIEKNN 877

Query: 719  DLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAK--IQERDLYIENIESELSKYKS 776
            ++      +  +K  E+  K   E +  +Q  F       I+E++ +IENI+ E    K+
Sbjct: 878  EIESFKNDIEQKKFKEM-EKFKEENEKLLQNNFENMKNHFIEEQNKHIENIKKEYELIKN 936

Query: 777  R-ICRLEESIAVMEDRRY-SLERK-ADQLGSYLQEKQKAYSE-YTIQEDELVNRLAVLMD 832
              I  L+E +   + +   ++E K AD+   ++ + +K     Y ++    +N L   ++
Sbjct: 937  NEIEYLKEEMKKNKIQEIENVELKLADEKNKHIDDMKKELENIYNVE----INNLKEKIN 992

Query: 833  HDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRT-DLAES 891
             ++ + +++LE +    E QK      E  Q L+I  ++M+   N L+E+   + DL   
Sbjct: 993  AEQTLAQEMLETQRNEYE-QKLEIQRNEYEQQLEIRRNEME---NKLIEQRKESYDLG-- 1046

Query: 892  ESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEK-- 949
              +K +++++ L   ++++  E + +I ++K ++E      N + E+ +   K L +   
Sbjct: 1047 --SKKESEIQILTDKIEKLKMEIE-IINKEKIDLEHNISILNDERENILNQNKNLEDNLK 1103

Query: 950  -----YEKNIEYVTQLEAQLQEYKNNI-ENLNMNVEELNKMNLELIDKHVQKQQTQSPDY 1003
                 Y K I  +   + +L++   +I EN     +++ +   +L+ + + + + +S + 
Sbjct: 1104 NNEDIYNKKINILNDEKLKLEKEIEHIKENGAKESDQIREQFADLLQEEIDRIKKESKEK 1163

Query: 1004 TEQYINEINKLNALLKQKDEEIIALNQKIN--NAQVSY-----MSMVSDYESKLAQFTTK 1056
               YI + N++N   ++K +E   L +K N  N Q++      +  +++YE  +     +
Sbjct: 1164 VNIYIQQYNEINEEYEEKKKEYNDLLEKANVSNKQLTEKCEENIQKINEYEDMIKMLENQ 1223

Query: 1057 LENM-EEEMQRVSKQLLDSKQ-HNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMII 1114
             E +  +++Q +++  L  K+  + E   L++  +  I E K  K   E N   +    I
Sbjct: 1224 TEVLVTKKIQELNEDFLKKKEAFDNEKNDLLKNYEHAITENKHIKEQLE-NFTNSNEEKI 1282

Query: 1115 SSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTK 1174
            S            +                +  E+ ++E++  ++    +N+   E  TK
Sbjct: 1283 SQIKNQYETQIKEMQIHFDELLNETKNKNNEMLEDIVKEQNDKEQSIQHMNSVNTELVTK 1342

Query: 1175 IIQLETLNTELTGHDVVNQEQINQLKSKLEQL-NTENDNLLSTVAELRSSISSAVDQRGF 1233
              QL    TE+       QE+ ++L  +   L N E    L  + +L +     V++   
Sbjct: 1343 NEQLNLNITEIKNELSNFQEKYDKLVKENNHLKNEEQTKFLDKILDLEN-----VNKHLM 1397

Query: 1234 EIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKI---VTME 1290
            E+ E  ++   +     +  ++++  Q   ++   ++L D +    +++ N I   V ++
Sbjct: 1398 EVTEKEREINIKNVNIIKSLQNQINEQTKLYKEYTDELKDEILQLKKQKKNSIDSNVPID 1457

Query: 1291 QVTSLQNKLQDKEEHLR 1307
              +S+ N L ++ + L+
Sbjct: 1458 ANSSINNALIEENKKLK 1474



 Score = 99.1 bits (236), Expect = 9e-19
 Identities = 180/890 (20%), Positives = 395/890 (44%), Gaps = 82/890 (9%)

Query: 461  EGPSLIHVGTNTEDVNEIAKVQ-EQLKQELNDEIK----DVNVKDLIEKLKSAEEQITQL 515
            E P +++  +NT + N I   + ++L Q + D IK    D N  ++   +K+  ++IT L
Sbjct: 546  ENPIILN-DSNTINKNNIIDAESDKLVQNILDMIKIKLQDDNKNNIDTIIKNESKRITSL 604

Query: 516  NDEIDAANKNMIKVKSNHKLKLKQMQKTI-DNFSKVSDSNKEIVRLTEELHHLSQKVAEL 574
             +E        +++  N   +LK+  + + D    + +   +I    ++ + ++  +  +
Sbjct: 605  LEE----KTGSMEILCNKICQLKKKNEDVEDKNDTIREETHQINIDKDKENEINNLLYVI 660

Query: 575  EEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETR----LKAISLLESQKFDLVQEL 630
              +   ++  L  + +   +   +  K  E+ N+ + R    L  I+ LE ++     E 
Sbjct: 661  NIKNKKIKEELEAFTNSFNVLKKLKMKNDEIINIYKNRENVFLTTINKLEEKRKLKYAEF 720

Query: 631  HILQQKYDEV---EDKLADISQLQSDQVCSEIKSVH--LEEQIDALSASKKELALVIENL 685
               +++Y E+   +++L  I Q+ + +     K+    L+++I  +    KE    IE L
Sbjct: 721  KEKEKQYKELIMKKEELLKIXQINNKKNIETFKNQEQMLKDEIQKIELKTKEK---IEEL 777

Query: 686  KLDKEQLYG-TIKDLENDKED-IMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEE 743
            K D E+     +++LE +KE  I N L+N I +   + +KLE+    +I E   K  ++ 
Sbjct: 778  KQDFEKTQKINMENLEMEKESFINNNLENEINK---MKEKLEEKYETQIKETEMKYKYQI 834

Query: 744  QSKIQ-TQFGIDAKIQER-DLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQ 801
            + +I+ T+   +     + + Y EN+E   + + + +  +E++  +   +    ++K  +
Sbjct: 835  KEEIEKTKQNAEQNFNSKFEKYKENLEKNKNDFINNLI-IEKNNEIESFKNDIEQKKFKE 893

Query: 802  LGSYLQEKQKAY-SEYTIQEDELVNRLAVLMDHDRVVEKQLL---EIEHENKELQKKNQI 857
            +  + +E +K   + +   ++  +      +++ +  E +L+   EIE+  +E+ KKN+I
Sbjct: 894  MEKFKEENEKLLQNNFENMKNHFIEEQNKHIENIKK-EYELIKNNEIEYLKEEM-KKNKI 951

Query: 858  LLEENQNLQISLSDMQ-QHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQT 916
              +E +N+++ L+D + +H + + ++       E  + K +    + E  L +   E Q 
Sbjct: 952  --QEIENVELKLADEKNKHIDDMKKELENIYNVEINNLKEKI---NAEQTLAQEMLETQR 1006

Query: 917  LIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNM 976
               ++K EI+  E E   +I     + K++ ++ E + +  ++ E+++Q   + IE L M
Sbjct: 1007 NEYEQKLEIQRNEYEQQLEIRRNEMENKLIEQRKE-SYDLGSKKESEIQILTDKIEKLKM 1065

Query: 977  NVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQ 1036
             +E +NK  ++L     +   +   D  E  +N+   L   LK  ++     N+KIN   
Sbjct: 1066 EIEIINKEKIDL-----EHNISILNDERENILNQNKNLEDNLKNNED---IYNKKIN--- 1114

Query: 1037 VSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELK 1096
                 +++D + KL +   ++E+++E   + S Q+       E+   L++E+ D+IK  K
Sbjct: 1115 -----ILNDEKLKLEK---EIEHIKENGAKESDQI------REQFADLLQEEIDRIK--K 1158

Query: 1097 ETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSV 1156
            E+K   ++NI   +   I+   E    + N++                ++ EE IQ+ + 
Sbjct: 1159 ESKE--KVNIYIQQYNEINEEYEEKKKEYNDL----LEKANVSNKQLTEKCEENIQKINE 1212

Query: 1157 LQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLST 1216
             ++    L  + +   TK IQ   LN +          + N L    E   TEN ++   
Sbjct: 1213 YEDMIKMLENQTEVLVTKKIQ--ELNEDFLKKKEAFDNEKNDLLKNYEHAITENKHIKEQ 1270

Query: 1217 VAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQ 1276
            +    +S    + Q   +     K+     +    +T+++    L     +      S+Q
Sbjct: 1271 LENFTNSNEEKISQIKNQYETQIKEMQIHFDELLNETKNKNNEMLEDIVKEQNDKEQSIQ 1330

Query: 1277 SSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSE 1326
                  T  +   EQ   L   + + +  L N QEKY  ++ +   L++E
Sbjct: 1331 HMNSVNTELVTKNEQ---LNLNITEIKNELSNFQEKYDKLVKENNHLKNE 1377



 Score = 70.9 bits (166), Expect = 3e-10
 Identities = 130/651 (19%), Positives = 271/651 (41%), Gaps = 50/651 (7%)

Query: 919  VQKKKEIEDLEIEFNTQIESAIR---DKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLN 975
            V+K +E E +E + N  + S      DK V  E    NI  + +    L +  N I   N
Sbjct: 505  VEKMEEFEKME-KSNEHVNSFSMFNLDKGVSVES-TSNIIAMDENPIILND-SNTINKNN 561

Query: 976  MNVEELNKMNLELIDKHVQKQQTQSPDYTEQYI-NEINKLNALLKQKDEEIIALNQKINN 1034
            +   E +K+   ++D    K Q  + +  +  I NE  ++ +LL++K   +  L  KI  
Sbjct: 562  IIDAESDKLVQNILDMIKIKLQDDNKNNIDTIIKNESKRITSLLEEKTGSMEILCNKICQ 621

Query: 1035 AQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKE 1094
             +      V D    + + T ++   +++   ++  L      N++++  +    +    
Sbjct: 622  LKKKNED-VEDKNDTIREETHQINIDKDKENEINNLLYVINIKNKKIKEELEAFTNSFNV 680

Query: 1095 LKETKLTFE--MNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQ 1152
            LK+ K+  +  +NI K    +  +TI  + ++   +               + ++EE ++
Sbjct: 681  LKKLKMKNDEIINIYKNRENVFLTTINKL-EEKRKLKYAEFKEKEKQYKELIMKKEELLK 739

Query: 1153 ERSVLQEQSAKLNTELQECYTKIIQLETLNT----ELTGHDVVNQEQINQLKSKLEQLNT 1208
               +  +++ +     ++     IQ   L T    E    D    ++IN    ++E+ + 
Sbjct: 740  IXQINNKKNIETFKNQEQMLKDEIQKIELKTKEKIEELKQDFEKTQKINMENLEMEKESF 799

Query: 1209 ENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKY 1268
             N+NL + + +++  +    +    +I E   ++  Q + + +KT+         F SK+
Sbjct: 800  INNNLENEINKMKEKLEEKYET---QIKETEMKYKYQIKEEIEKTKQNAEQN---FNSKF 853

Query: 1269 EQLLDSVQSSTQEETNKIVTME--QVTSLQNKLQDKE-EHLRNLQEKYADVI-NQIEILR 1324
            E+  ++++ +  +  N ++  +  ++ S +N ++ K+ + +   +E+   ++ N  E ++
Sbjct: 854  EKYKENLEKNKNDFINNLIIEKNNEIESFKNDIEQKKFKEMEKFKEENEKLLQNNFENMK 913

Query: 1325 SEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXX 1384
            +   +E+                   +   E     ++QE   + +   + + K      
Sbjct: 914  NHFIEEQNKHIENIKKEYELIKNNEIEYLKEEMKKNKIQEIENVELKLADEKNKHIDDMK 973

Query: 1385 XXXXXXXXXRVNDAEAKV-LELT---HQLELKDSEIYQKT----HEYTITLTQRNDEFEN 1436
                      +N+ + K+  E T     LE + +E  QK     +EY   L  R +E EN
Sbjct: 974  KELENIYNVEINNLKEKINAEQTLAQEMLETQRNEYEQKLEIQRNEYEQQLEIRRNEMEN 1033

Query: 1437 VRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKIT 1496
               +L+E  K   DL  +KESE+ IL  K+ +     E + KE      K+  E N+ I 
Sbjct: 1034 ---KLIEQRKESYDLGSKKESEIQILTDKIEKLKMEIEIINKE------KIDLEHNISIL 1084

Query: 1497 ESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMV 1547
                 N  +   NK LE+ + K NE    + N++I I  LNDE   L+  +
Sbjct: 1085 NDEREN--ILNQNKNLEDNL-KNNE---DIYNKKINI--LNDEKLKLEKEI 1127



 Score = 64.5 bits (150), Expect = 2e-08
 Identities = 161/811 (19%), Positives = 334/811 (41%), Gaps = 97/811 (11%)

Query: 831  MDHDRVVEK--QLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALV----EKAN 884
            M+    VEK  +  ++E  N+ +   +   L++  +++ + + +    N ++       N
Sbjct: 499  MEKMEKVEKMEEFEKMEKSNEHVNSFSMFNLDKGVSVESTSNIIAMDENPIILNDSNTIN 558

Query: 885  RTDLAESESTKYQTQLRDLESNLKRITHEHQ--TLIVQKKKEIEDLEIEFNTQIESAIRD 942
            + ++ ++ES K    + D+     +  +++   T+I  + K I  L  E    +E  I  
Sbjct: 559  KNNIIDAESDKLVQNILDMIKIKLQDDNKNNIDTIIKNESKRITSLLEEKTGSME--ILC 616

Query: 943  KKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPD 1002
             K+   K +KN +    +E +    +     +N++ ++ N++N  L   +++ ++ +  +
Sbjct: 617  NKICQLK-KKNED----VEDKNDTIREETHQINIDKDKENEINNLLYVINIKNKKIK--E 669

Query: 1003 YTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYES-KLAQFTTKLENME 1061
              E + N  N L  L K K++EII + +   N  ++ ++ + +    K A+F  K E   
Sbjct: 670  ELEAFTNSFNVLKKL-KMKNDEIINIYKNRENVFLTTINKLEEKRKLKYAEFKEK-EKQY 727

Query: 1062 EEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPM 1121
            +E+    ++LL   Q N +  I   +  +Q+  LK+     E+   +    +     +  
Sbjct: 728  KELIMKKEELLKIXQINNKKNIETFKNQEQM--LKDEIQKIELKTKEKIEELKQDFEKTQ 785

Query: 1122 SDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETL 1181
              +  N++             ++ + +E ++E+   Q +  ++  + Q      I+ E  
Sbjct: 786  KINMENLEMEKESFINNNLENEINKMKEKLEEKYETQIKETEMKYKYQ------IKEEIE 839

Query: 1182 NTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSA---VDQRGFEIAEL 1238
             T+       N +   + K  LE+   +ND + + + E  + I S    ++Q+ F+  E 
Sbjct: 840  KTKQNAEQNFNSK-FEKYKENLEK--NKNDFINNLIIEKNNEIESFKNDIEQKKFKEMEK 896

Query: 1239 WKQH---LAQREADFQKTE--HELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVT 1293
            +K+    L Q   +  K     E    +   + +YE + ++     +EE  K   ++++ 
Sbjct: 897  FKEENEKLLQNNFENMKNHFIEEQNKHIENIKKEYELIKNNEIEYLKEEMKKN-KIQEIE 955

Query: 1294 SLQNKLQD-KEEHLRNLQEKYADVIN-QIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXD 1351
            +++ KL D K +H+ +++++  ++ N +I  L+ +I  E+                    
Sbjct: 956  NVELKLADEKNKHIDDMKKELENIYNVEINNLKEKINAEQTL---AQEMLETQRNEYEQK 1012

Query: 1352 LRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLEL 1411
            L  +   Y+Q  E   +  NE   +L +               +     K+ +L  ++E+
Sbjct: 1013 LEIQRNEYEQQLE---IRRNEMENKLIEQRKESYDLGSKKESEIQILTDKIEKLKMEIEI 1069

Query: 1412 KDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYE---KRIEDLTYEKESELAILRLKMHE 1468
             + E     H  +I     NDE EN+  Q    E   K  ED+  +K + L   +LK+ +
Sbjct: 1070 INKEKIDLEHNISIL----NDERENILNQNKNLEDNLKNNEDIYNKKINILNDEKLKLEK 1125

Query: 1469 NANHY-ETMQKES-------------EIERVKLI--EELNVKITESVSLNKQVAEL---- 1508
               H  E   KES             EI+R+K    E++N+ I +   +N++  E     
Sbjct: 1126 EIEHIKENGAKESDQIREQFADLLQEEIDRIKKESKEKVNIYIQQYNEINEEYEEKKKEY 1185

Query: 1509 ----------NKAL----EEEVAKTNE---MQTALENQEIEIVT-----LNDEITNLQNM 1546
                      NK L    EE + K NE   M   LENQ   +VT     LN++    +  
Sbjct: 1186 NDLLEKANVSNKQLTEKCEENIQKINEYEDMIKMLENQTEVLVTKKIQELNEDFLKKKEA 1245

Query: 1547 VRASSSKIQKHVSFASDTKQGRDEQLDNTMN 1577
                 + + K+   A    +   EQL+N  N
Sbjct: 1246 FDNEKNDLLKNYEHAITENKHIKEQLENFTN 1276



 Score = 59.3 bits (137), Expect = 9e-07
 Identities = 145/782 (18%), Positives = 307/782 (39%), Gaps = 58/782 (7%)

Query: 845  EHENKELQKKNQILLEENQN-LQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDL 903
            E     L K +  +L+ N+N +    + +       + K N  +L E    KY ++  D 
Sbjct: 205  EEFTNNLNKISDNVLDGNKNNIPFESNHINDKERTSLSKDNLFNLNEINKNKYDSKNDDN 264

Query: 904  ESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIE-SAIRDKKVLNEK-YEKNIEYV---T 958
             +NL  +  E+QTLI  K  E+ ++E       E + + + ++   K    NI       
Sbjct: 265  NNNL--LFSENQTLIPAKVNEVTEIEASRTPNYEINRVPNYEINKSKGIHPNIPQFNNPA 322

Query: 959  QLEAQLQEYKNNI--ENLNMNVEELNKM-NLELIDKHVQKQQTQSPDYTEQYINEINKLN 1015
            QL  ++   KNNI  +N++  +     + NLE  +K +++    + ++     N INK N
Sbjct: 323  QLPTEI-NIKNNINYDNISPKINSKGVIENLENKNKEIKRISMDNFEFNNPISNHINKRN 381

Query: 1016 ALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENM--EEEMQRVSKQLLD 1073
            +           + + + N Q+ Y ++ ++   K         N+  E ++  +S ++++
Sbjct: 382  S---------TTVVRSVFNPQLEYNNVENNEIRKFNTIGNNYMNIGRENDILNISPKVIE 432

Query: 1074 SKQHNEELQILVREQDDQIKELKETKLTFEM---NIPKTEGMIISSTIEPMSDDANNVDX 1130
                    Q+     +    +L   K+T      NI       +S+ I         V+ 
Sbjct: 433  KINRRNTHQLFNESSNISTDKLTIHKVTSPFLFDNINNDSNTNVSNEIPEKGGKMEKVEK 492

Query: 1131 XXXXXXXXXXXLKVQEEEEFIQ-ERSVLQEQS-AKLNTE---LQECYTKIIQLETLNTEL 1185
                        KV++ EEF + E+S     S +  N +     E  + II ++     L
Sbjct: 493  MEKMEKMEKME-KVEKMEEFEKMEKSNEHVNSFSMFNLDKGVSVESTSNIIAMDENPIIL 551

Query: 1186 TGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQ 1245
               + +N+  I   +S     N  +   +    + +++I + +      I  L ++    
Sbjct: 552  NDSNTINKNNIIDAESDKLVQNILDMIKIKLQDDNKNNIDTIIKNESKRITSLLEEKTGS 611

Query: 1246 READFQKTEHELRVQLSAFESKYEQLLDSVQ--SSTQEETNKIVTMEQVTSLQNKLQDKE 1303
             E    K   +L+ +    E K + + +     +  +++ N+I  +  V +++NK + KE
Sbjct: 612  MEILCNKI-CQLKKKNEDVEDKNDTIREETHQINIDKDKENEINNLLYVINIKNK-KIKE 669

Query: 1304 EHLRNLQEKYADVINQIEILRSEI----EDEKVAFXXXXXXXXXXXXXXXXDLRTENQSY 1359
            E L      + +V+ ++++   EI    ++ +  F                + + + + Y
Sbjct: 670  E-LEAFTNSF-NVLKKLKMKNDEIINIYKNRENVFLTTINKLEEKRKLKYAEFKEKEKQY 727

Query: 1360 KQ--MQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIY 1417
            K+  M+++ +L I + N   KK+              +   E K  E   +L+ +D E  
Sbjct: 728  KELIMKKEELLKIXQINN--KKNIETFKNQEQMLKDEIQKIELKTKEKIEELK-QDFEKT 784

Query: 1418 QKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQ 1477
            QK +   + + + +    N+  ++ + ++++E+  YE + +   ++ K        +T Q
Sbjct: 785  QKINMENLEMEKESFINNNLENEINKMKEKLEE-KYETQIKETEMKYKYQIKEEIEKTKQ 843

Query: 1478 KESEIERVKLIE-ELNVKITESVSLNKQVAELNKALEE-----EVAKTNEMQTALENQEI 1531
               +    K  + + N++  ++  +N  + E N  +E      E  K  EM+   E  E 
Sbjct: 844  NAEQNFNSKFEKYKENLEKNKNDFINNLIIEKNNEIESFKNDIEQKKFKEMEKFKEENE- 902

Query: 1532 EIVTLNDEITNLQN-MVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELD 1590
                L +   N++N  +   +  I+         K    E L   M K  +  +   EL 
Sbjct: 903  --KLLQNNFENMKNHFIEEQNKHIENIKKEYELIKNNEIEYLKEEMKKNKIQEIENVELK 960

Query: 1591 LA 1592
            LA
Sbjct: 961  LA 962


>UniRef50_UPI00006A154D Cluster: Centrosomal protein 2 (Centrosomal
            Nek2-associated protein 1) (C-NAP1) (Centrosome protein
            250) (Centrosome-associated protein CEP250).; n=1;
            Xenopus tropicalis|Rep: Centrosomal protein 2
            (Centrosomal Nek2-associated protein 1) (C-NAP1)
            (Centrosome protein 250) (Centrosome-associated protein
            CEP250). - Xenopus tropicalis
          Length = 1575

 Score =  129 bits (311), Expect = 7e-28
 Identities = 280/1436 (19%), Positives = 591/1436 (41%), Gaps = 137/1436 (9%)

Query: 216  QQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLA 275
            Q++ ++QE+   +    +     L  +I  +  +    E A + LEA   ++  E  +L 
Sbjct: 173  QRIERLQESEKELALAREQLHSELSAEIAKRQHQAQESEGAKESLEAELADVMGERERLQ 232

Query: 276  QEL---EQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLE 332
             EL    Q              L KQ +    +    ++E+   EI ++ E  ++ +   
Sbjct: 233  AELTQDSQTEKETALYNLEHQTLMKQELSRETQLNLTVQER-EREIRSLKENIQRAQQEN 291

Query: 333  HLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRK-SGRNTASKMKSPWSQLSS 391
                QIR+  K+ E     M  E  +  + S+KG  +   K S +    KM++   ++ S
Sbjct: 292  EAAEQIRECEKDRE---TAMKAEESSRITLSEKGREISKMKESEKEHQFKMENALKEIES 348

Query: 392  ETL---NQDTDKKINKNEIAKLEMVIQSLNKDLVDKE-YVISEKDTXXXXXXXXXXGKDT 447
            +T+    +DT  +  K  + + E  I  +N+    K   ++ E++            +  
Sbjct: 349  QTIILREKDTFLETLKQRLKECEEEI--MNELQRQKHMLIVEERERDIKILQESVQREKD 406

Query: 448  LIAQL------QLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDL 501
            ++  +      Q E  +  +  +LI      E+     K+ ++  Q   D +K ++    
Sbjct: 407  MVKHISDQWESQRESSERQKESTLIQHRLIVEERERDIKILQESVQRERDMVKHIS-DQW 465

Query: 502  IEKLKSAEEQ----ITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSD----S 553
              + +SAE Q    I++L+  +    +    ++   K     +Q+ +D+ ++  +    +
Sbjct: 466  ESQRESAERQKENKISELSQALSKKEREAELLERQTKRDSDLLQEQLDSLTQHLEEKEIA 525

Query: 554  NKEIVRLTEELHHLSQKVAEL---EEEKGN----LQLHLVDYDSGRMIESDVYKKMIEME 606
            +K+   L  E   L QKV+EL   EE +      LQ  L +  S  + E+++  + I+  
Sbjct: 526  HKKNSELQRENMALEQKVSELTQAEEHREKDIKFLQERLKEL-SQTLTENEIGTERIKQH 584

Query: 607  NLAET-RLK--------AISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCS 657
               +T  LK        A+++ ++++ + ++++  L+++ +  E  L+D  +   D+   
Sbjct: 585  AEKDTSALKVRVSELSAALTMRDTKELETLEQIKSLKREIESCEMALSDKEKRAEDERRQ 644

Query: 658  EIKSV-HLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNK--LQNYI 714
              K +  + +++  LS +     +  E  +++   L G +++LE+  E+   K  ++  I
Sbjct: 645  SEKEISSVRQRVTELSEAIMSKEIQQEEREIEVRALKGRLEELEHALEESAEKSRVERQI 704

Query: 715  QENMDLTDKLEKM-SAEKISELLAKINHEEQSKIQ---TQFGIDAKIQERDLYIENIESE 770
            +E   L  + E    A K  E     +H E+  ++    +   D   +ERD      E E
Sbjct: 705  REGDTLIQRAELFGKALKEKERRHMDDHREKEMLRQRVNELSQDIINKERD-----AEEE 759

Query: 771  LSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVL 830
            L   + +   L +++   E+ +   +R+++     L+ K     +  ++E+ +     V 
Sbjct: 760  LKALRRKTVELRQTLIEKEEDKAEEQRRSENEKEALRHKATGLLQ-ALEEERMA--AEVR 816

Query: 831  MDHDRVVEKQLLEIEHENKELQKKNQILLE---ENQNLQISLSDMQQHYNAL-------- 879
                 +  + LLE E E ++ +K+ Q L +   E + LQ  ++ +++    L        
Sbjct: 817  QGRLEITSQALLEKEIETEKQEKERQTLDKKDREGETLQEEMAAVRRKREELGQALRDKE 876

Query: 880  VEKANRTDLAESESTKYQTQLRDLESNLKR------ITHEHQTLIVQKKKEI-EDLEIEF 932
             EK       E E+     +++DL   L        I  E  T + +K +E+ + L+ + 
Sbjct: 877  QEKCEADTQKEKENESLSKKVKDLSQALLEKEREADILQEEVTAVRRKGEELKQTLKDKE 936

Query: 933  NTQIESAIRDKK---VLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELI 989
              +IE  ++++K    L+ K E   + + + E +    +  +  +    EEL +   +  
Sbjct: 937  QDKIEKEVQNEKEREALSLKVEHLSQALLEKEREADTLQEEVTAVRRKGEELKQTLKDKE 996

Query: 990  DKHVQKQQTQSPDYTEQYINEINKLNALLKQKD-------EEIIALNQKINNAQVSYMSM 1042
             K ++K + Q+    E    ++ +L+  L +K+       EE+ AL +K    + +  + 
Sbjct: 997  QKKIEK-EVQNDKEKEALSQKVKQLSQALLEKEREADTLQEEVAALRRKGEELKQTLKNK 1055

Query: 1043 VSDYESKLAQFTTKLENMEEEMQRVSKQLLD-------SKQHNEELQILVRE----QDDQ 1091
              ++  K  Q   + E   ++++ +S+ LL+       +K   E+L I +R+    Q + 
Sbjct: 1056 EQEHIEKEVQNEKEKEAQSQKVEHLSQALLEKESEVELTKGKKEDLTIQIRDLRQFQLEN 1115

Query: 1092 IKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFI 1151
             KE+KE +    + + +    +I+ T++   ++   ++            LKV+E EE  
Sbjct: 1116 EKEIKEEERQSRLKVTELSETLINKTLQ---EEEKQLE--VKSLKGKTLKLKVKECEEEK 1170

Query: 1152 QERSVLQEQSAKLNTELQECYTKIIQLE-TLNT--ELTGHDVVNQEQINQLKSKLEQLNT 1208
            +ER  L ++ ++L+  L E       +E  +NT  E  G       +  Q K++  Q   
Sbjct: 1171 KERKKLNQKVSELSQALLEKQRNSEMIEQEMNTLREKIGESGKALIEKEQEKAEARQSVK 1230

Query: 1209 ENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKY 1268
            E + L   VAEL  ++     QR  E+ E     L ++  +  K         +  E + 
Sbjct: 1231 EKETLRQKVAELSQALLE--KQRNSEMIEQEMNSLREKIGETGK---------AFIEKEQ 1279

Query: 1269 EQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQI-----EIL 1323
            E+  +  QS  + ET +    E   +L  K +D  + L +L+EK  ++   +     EI 
Sbjct: 1280 EKAEEGRQSVKESETLRQKVAELSQALLQKERDVGQELVSLREKIGELAQTLVKKEKEIK 1339

Query: 1324 RSEIEDEKVAFXXXXXXXXXXXXXXXXDLR-TENQSYKQ-MQEQSILNINEENAQLKKSS 1381
              E E E+V                  +L  TE ++ ++ + E  ++ IN+E  +L +  
Sbjct: 1340 EGEQEKEEVKLKLTSLCQSLKEKETEVELTGTELKATREKVGELRLVLINKER-ELNEEK 1398

Query: 1382 XXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQL 1441
                        RV      ++E    L  K+ E+ +   +  I +    ++   +    
Sbjct: 1399 RQSECEKEELKQRVESLSQALVEKDRALIEKEEEVKEGAKQSKIEVEALRNQLVQLELAQ 1458

Query: 1442 VEYEKRIEDLTYEKE--------SELAILRLKMHENANHYETMQKESEIERVKLIEELNV 1493
             +  +   DL  EK+        SE    R+ + E         K  E++++K  EE +V
Sbjct: 1459 AQEMQEKGDLQDEKDRQAKEQQISESEKERMALGERIIEISRDLKRREVKQIK-EEEESV 1517

Query: 1494 KITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRA 1549
             + +  +L K+  E  +  E    +    + AL + E E +   ++   L++  RA
Sbjct: 1518 SLQKIETLQKENKEGKQREERLKHRLRRTEMALRHTESEEIAWREKARELESKYRA 1573



 Score =  105 bits (252), Expect = 1e-20
 Identities = 201/1097 (18%), Positives = 455/1097 (41%), Gaps = 80/1097 (7%)

Query: 536  KLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIE 595
            +L+ M+  ++   +V  S +  V   E+   +     +LE  K + Q  +      +  E
Sbjct: 34   ELRSMRSQVETADEVERSLRSQVATLEQ--DIRSTRLQLETSKEDTQ-SMTSRLEAQKEE 90

Query: 596  SDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQV 655
            + + +  +E E   ET    +   E +   L Q++ + + +   V  +LA  S L+++ +
Sbjct: 91   AAILRSQLEAEE--ETSQLKLKASEQEIKALRQQIQMSEAELSFVRSELAG-STLEAESL 147

Query: 656  CSEIKSVHLE---------------EQIDALSASKKELALVIENL--KLDKE--QLYGTI 696
             S +++  +E               ++I+ L  S+KELAL  E L  +L  E  +     
Sbjct: 148  KSRLETYEMEAKSRLEDKKQELRISQRIERLQESEKELALAREQLHSELSAEIAKRQHQA 207

Query: 697  KDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEE--QSKIQTQFGID 754
            ++ E  KE +  +L + + E   L  +L + S  +    L  + H+   + ++  +  ++
Sbjct: 208  QESEGAKESLEAELADVMGERERLQAELTQDSQTEKETALYNLEHQTLMKQELSRETQLN 267

Query: 755  AKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSY-LQEKQKAY 813
              +QER+  I +++  + + +      E+     +DR  ++  KA++     L EK +  
Sbjct: 268  LTVQEREREIRSLKENIQRAQQENEAAEQIRECEKDRETAM--KAEESSRITLSEKGREI 325

Query: 814  SEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQ 873
            S+    E E   ++   +   + +E Q + +  ++  L+   Q L E  + +   L   +
Sbjct: 326  SKMKESEKEHQFKMENAL---KEIESQTIILREKDTFLETLKQRLKECEEEIMNEL--QR 380

Query: 874  QHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFN 933
            Q +  +VE+  R      ES + +  +      +K I+ + ++     +++ E   I+  
Sbjct: 381  QKHMLIVEERERDIKILQESVQREKDM------VKHISDQWESQRESSERQKESTLIQHR 434

Query: 934  TQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMN-VEELNKMNLELIDKH 992
              +E   RD K+L E  ++  + V  +  Q +  + + E    N + EL++  L   ++ 
Sbjct: 435  LIVEERERDIKILQESVQRERDMVKHISDQWESQRESAERQKENKISELSQA-LSKKERE 493

Query: 993  VQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQ 1052
             +  + Q+   ++    +++ L   L++K E     N ++    ++    VS+       
Sbjct: 494  AELLERQTKRDSDLLQEQLDSLTQHLEEK-EIAHKKNSELQRENMALEQKVSELTQAEEH 552

Query: 1053 FTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGM 1112
                ++ ++E ++ +S+ L +++   E ++    E+D    +++ ++L+  + +  T+ +
Sbjct: 553  REKDIKFLQERLKELSQTLTENEIGTERIK-QHAEKDTSALKVRVSELSAALTMRDTKEL 611

Query: 1113 IISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQS-AKLNTELQEC 1171
                 I+ +  +  + +             + Q E+E    R  + E S A ++ E+Q+ 
Sbjct: 612  ETLEQIKSLKREIESCEMALSDKEKRAEDERRQSEKEISSVRQRVTELSEAIMSKEIQQ- 670

Query: 1172 YTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQR 1231
              + I++  L   L   +   +E     KS++E+   E D L+   AEL        ++R
Sbjct: 671  EEREIEVRALKGRLEELEHALEESAE--KSRVERQIREGDTLIQR-AELFGKALKEKERR 727

Query: 1232 GFE---IAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLL--------DSVQSSTQ 1280
              +     E+ +Q + +   D    E +   +L A   K  +L         D  +   +
Sbjct: 728  HMDDHREKEMLRQRVNELSQDIINKERDAEEELKALRRKTVELRQTLIEKEEDKAEEQRR 787

Query: 1281 EETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXX 1340
             E  K     + T L   L++ E     +++   ++ +Q  +L  EIE EK         
Sbjct: 788  SENEKEALRHKATGLLQALEE-ERMAAEVRQGRLEITSQ-ALLEKEIETEK---QEKERQ 842

Query: 1341 XXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEA 1400
                       L+ E  + ++ +E+    + ++  +  ++             +V D   
Sbjct: 843  TLDKKDREGETLQEEMAAVRRKREELGQALRDKEQEKCEADTQKEKENESLSKKVKDLSQ 902

Query: 1401 KVLELTHQLELKDSEIYQ-KTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESEL 1459
             +LE   + ++   E+   +     +  T ++ E + + ++ V+ EK  E L+ + E   
Sbjct: 903  ALLEKEREADILQEEVTAVRRKGEELKQTLKDKEQDKIEKE-VQNEKEREALSLKVEH-- 959

Query: 1460 AILRLKMHENANHYETMQKESEIERVKLIE-ELNVKITESVSLNKQVAELNKALEEEVAK 1518
              L   + E     +T+Q+E    R K  E +  +K  E   + K+V + +K  E    K
Sbjct: 960  --LSQALLEKEREADTLQEEVTAVRRKGEELKQTLKDKEQKKIEKEV-QNDKEKEALSQK 1016

Query: 1519 TNEMQTALENQEIEIVTLNDEITNL----QNMVRASSSKIQKHVSFASDTKQGRDEQLDN 1574
              ++  AL  +E E  TL +E+  L    + + +   +K Q+H+      ++ ++ Q   
Sbjct: 1017 VKQLSQALLEKEREADTLQEEVAALRRKGEELKQTLKNKEQEHIEKEVQNEKEKEAQSQK 1076

Query: 1575 T--MNKELLDAVPRAEL 1589
               +++ LL+     EL
Sbjct: 1077 VEHLSQALLEKESEVEL 1093



 Score = 99.1 bits (236), Expect = 9e-19
 Identities = 260/1273 (20%), Positives = 542/1273 (42%), Gaps = 119/1273 (9%)

Query: 313  KGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISR 372
            +  +E A+  E + + ++   L   IR T  +LE       + +  + +  ++ + L S+
Sbjct: 39   RSQVETADEVERSLRSQVAT-LEQDIRSTRLQLETSKEDTQSMTSRLEAQKEEAAILRSQ 97

Query: 373  KSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKD 432
                   S++K   S+   + L Q    +I  +E A+L  V   L    ++ E + S  +
Sbjct: 98   LEAEEETSQLKLKASEQEIKALRQ----QIQMSE-AELSFVRSELAGSTLEAESLKSRLE 152

Query: 433  TXXXXXXXXXXGK-DTLIAQLQLEHQQHMEGP-SLIHVGTNTEDVNEIAKVQEQLKQ-EL 489
            T           K   L    ++E  Q  E   +L     ++E   EIAK Q Q ++ E 
Sbjct: 153  TYEMEAKSRLEDKKQELRISQRIERLQESEKELALAREQLHSELSAEIAKRQHQAQESEG 212

Query: 490  NDEIKDVNVKDLI---EKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDN 546
              E  +  + D++   E+L++   Q +Q   E    N     +      +  Q+  T+  
Sbjct: 213  AKESLEAELADVMGERERLQAELTQDSQTEKETALYNLEHQTLMKQELSRETQLNLTVQE 272

Query: 547  FSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEM- 605
              +   S KE ++  ++ +  ++++ E E+++   +  +   +S R+  S+  +++ +M 
Sbjct: 273  REREIRSLKENIQRAQQENEAAEQIRECEKDR---ETAMKAEESSRITLSEKGREISKMK 329

Query: 606  ENLAETRLK---AISLLESQKFDLVQE---LHILQQKYDEVEDKLADISQLQSDQVCSEI 659
            E+  E + K   A+  +ESQ   L ++   L  L+Q+  E E+++ +  Q Q   +  E 
Sbjct: 330  ESEKEHQFKMENALKEIESQTIILREKDTFLETLKQRLKECEEEIMNELQRQKHMLIVEE 389

Query: 660  KSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMD 719
            +    E  I  L  S +    +++++    +Q     +  E  KE  + +    I E  +
Sbjct: 390  R----ERDIKILQESVQREKDMVKHIS---DQWESQRESSERQKESTLIQ-HRLIVEERE 441

Query: 720  LTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRIC 779
               K+ + S ++  +++  I+ + +S+ ++     A+ Q+     EN  SELS+  S+  
Sbjct: 442  RDIKILQESVQRERDMVKHISDQWESQRES-----AERQK-----ENKISELSQALSKKE 491

Query: 780  RLEESIAVMEDRRYS--LERKADQLGSYLQEKQKAY---SEYTIQEDELVNRLAVLMDHD 834
            R E  +   + +R S  L+ + D L  +L+EK+ A+   SE   +   L  +++ L   +
Sbjct: 492  R-EAELLERQTKRDSDLLQEQLDSLTQHLEEKEIAHKKNSELQRENMALEQKVSELTQAE 550

Query: 835  RVVEKQLLEIEHENKELQK---KNQILLEE-NQNLQISLSDMQQHYNALVEKANRTDLAE 890
               EK +  ++   KEL +   +N+I  E   Q+ +   S ++   + L       D  E
Sbjct: 551  EHREKDIKFLQERLKELSQTLTENEIGTERIKQHAEKDTSALKVRVSELSAALTMRDTKE 610

Query: 891  SESTKYQTQL-RDLESNLKRITHEHQTLIVQKK---KEIEDLEIEFNTQIESAIRDKKVL 946
             E+ +    L R++ES    ++ + +    +++   KEI  +     T++  AI  K++ 
Sbjct: 611  LETLEQIKSLKREIESCEMALSDKEKRAEDERRQSEKEISSVRQRV-TELSEAIMSKEIQ 669

Query: 947  NEKYEKNIEYVTQLEAQLQEYKNNIEN------LNMNVEELNKM--NLELIDKHV-QKQQ 997
             E  E+ IE V  L+ +L+E ++ +E       +   + E + +    EL  K + +K++
Sbjct: 670  QE--EREIE-VRALKGRLEELEHALEESAEKSRVERQIREGDTLIQRAELFGKALKEKER 726

Query: 998  TQSPDYTE-----QYINEINKLNALLKQKD--EEIIALNQKINNAQVSYMSMVSDYESKL 1050
                D+ E     Q +NE+++ + + K++D  EE+ AL +K     V     + + E   
Sbjct: 727  RHMDDHREKEMLRQRVNELSQ-DIINKERDAEEELKALRRKT----VELRQTLIEKEEDK 781

Query: 1051 AQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTE 1110
            A+   + EN +E ++  +  LL   Q  EE ++    +  +++   +  L  E+   K E
Sbjct: 782  AEEQRRSENEKEALRHKATGLL---QALEEERMAAEVRQGRLEITSQALLEKEIETEKQE 838

Query: 1111 GMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQE 1170
                  T++    +   +             L  Q   +  QE+     Q  K N  L +
Sbjct: 839  KE--RQTLDKKDREGETLQEEMAAVRRKREELG-QALRDKEQEKCEADTQKEKENESLSK 895

Query: 1171 CYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLN-TENDNLLSTVAELRSSISSAVD 1229
               K+  L     E      + QE++  ++ K E+L  T  D     + +         +
Sbjct: 896  ---KVKDLSQALLEKEREADILQEEVTAVRRKGEELKQTLKDKEQDKIEK------EVQN 946

Query: 1230 QRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTM 1289
            ++  E   L  +HL+Q   + ++    L+ +++A   K E+L  +++   Q++  K V  
Sbjct: 947  EKEREALSLKVEHLSQALLEKEREADTLQEEVTAVRRKGEELKQTLKDKEQKKIEKEVQN 1006

Query: 1290 E-QVTSLQNKLQDKEEHLRNLQEKYADVINQ-IEILRSEIEDEKVAFXXXXXXXXXXXXX 1347
            + +  +L  K++   + L   +E+ AD + + +  LR + E+ K                
Sbjct: 1007 DKEKEALSQKVKQLSQALLE-KEREADTLQEEVAALRRKGEELKQTLKNKEQEHIEKEVQ 1065

Query: 1348 XXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVN-DAEAKVLELT 1406
               +   ++Q  + +  Q++L   E   +L K              +   + E ++ E  
Sbjct: 1066 NEKEKEAQSQKVEHLS-QALLE-KESEVELTKGKKEDLTIQIRDLRQFQLENEKEIKEEE 1123

Query: 1407 HQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLV-------EYEKRIEDLTYEKESEL 1459
             Q  LK +E+ +     T+   ++  E ++++ + +       E EK+      +K SEL
Sbjct: 1124 RQSRLKVTELSETLINKTLQEEEKQLEVKSLKGKTLKLKVKECEEEKKERKKLNQKVSEL 1183

Query: 1460 AILRLKMHENANHYE----TMQKESEIERVKLIE------ELNVKITESVSLNKQVAELN 1509
            +   L+   N+   E    T++++       LIE      E    + E  +L ++VAEL+
Sbjct: 1184 SQALLEKQRNSEMIEQEMNTLREKIGESGKALIEKEQEKAEARQSVKEKETLRQKVAELS 1243

Query: 1510 KALEEEVAKTNEM 1522
            +AL E+  + +EM
Sbjct: 1244 QALLEK-QRNSEM 1255



 Score = 99.1 bits (236), Expect = 9e-19
 Identities = 199/1019 (19%), Positives = 418/1019 (41%), Gaps = 73/1019 (7%)

Query: 170  TTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAME 229
            T  L+ +E  ++K+  ++ +N A                   +  ++++ ++ +     E
Sbjct: 516  TQHLEEKEIAHKKNSELQRENMALEQKVSELTQAEEHREKDIKFLQERLKELSQTLTENE 575

Query: 230  AEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXX 289
               +  KQ   KD  +  VR+S L  A  + +    E   +   L +E+E          
Sbjct: 576  IGTERIKQHAEKDTSALKVRVSELSAALTMRDTKELETLEQIKSLKREIESCEMALSDKE 635

Query: 290  XXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKL 349
                   +QS +     +  + E   L  A M++  ++ E    +   ++   +ELE+ L
Sbjct: 636  KRAEDERRQSEKEISSVRQRVTE---LSEAIMSKEIQQEEREIEVRA-LKGRLEELEHAL 691

Query: 350  ATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKS-------PWSQLSSETLNQDTDKKI 402
                 +S+ V    ++G  LI R      A K K           ++  + +N+ +   I
Sbjct: 692  EESAEKSR-VERQIREGDTLIQRAELFGKALKEKERRHMDDHREKEMLRQRVNELSQDII 750

Query: 403  NKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEG 462
            NK   A+ E  +++L +  V+    + EK+            +   +        Q +E 
Sbjct: 751  NKERDAEEE--LKALRRKTVELRQTLIEKEEDKAEEQRRSENEKEALRHKATGLLQALEE 808

Query: 463  PSL-IHVGTNTEDVNEIAKVQEQLKQELND-EIKDVNVKDLI-EKLKSAEEQITQLNDEI 519
              +   V     ++   A ++++++ E  + E + ++ KD   E L+     + +  +E+
Sbjct: 809  ERMAAEVRQGRLEITSQALLEKEIETEKQEKERQTLDKKDREGETLQEEMAAVRRKREEL 868

Query: 520  DAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKG 579
              A ++  + K     + ++  +++    KV D ++ ++    E   L ++V  +  +  
Sbjct: 869  GQALRDKEQEKCEADTQKEKENESLS--KKVKDLSQALLEKEREADILQEEVTAVRRKGE 926

Query: 580  NLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDE 639
             L+  L D       E D  +K ++ E   E     +  L     +  +E   LQ++   
Sbjct: 927  ELKQTLKDK------EQDKIEKEVQNEKEREALSLKVEHLSQALLEKEREADTLQEEVTA 980

Query: 640  VEDKLADISQLQSDQVCSEI-KSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKD 698
            V  K  ++ Q   D+   +I K V  +++ +ALS   K+L+  +   + + + L   +  
Sbjct: 981  VRRKGEELKQTLKDKEQKKIEKEVQNDKEKEALSQKVKQLSQALLEKEREADTLQEEVAA 1040

Query: 699  LENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGID-AKI 757
            L    E++   L+N  QE+++   + EK   EK ++   K+ H  Q+ ++ +  ++  K 
Sbjct: 1041 LRRKGEELKQTLKNKEQEHIEKEVQNEK---EKEAQ-SQKVEHLSQALLEKESEVELTKG 1096

Query: 758  QERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYT 817
            ++ DL I+    +L ++     +LE    + E+ R S   K  +L   L  K       T
Sbjct: 1097 KKEDLTIQ--IRDLRQF-----QLENEKEIKEEERQS-RLKVTELSETLINK-------T 1141

Query: 818  IQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNL---QISLSDMQQ 874
            +QE+E   +L V     + ++ ++ E E E KE +K NQ + E +Q L   Q +   ++Q
Sbjct: 1142 LQEEE--KQLEVKSLKGKTLKLKVKECEEEKKERKKLNQKVSELSQALLEKQRNSEMIEQ 1199

Query: 875  HYNALVEKANRTDLA----ESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEI 930
              N L EK   +  A    E E  + +  +++ E+  +++    Q L+ +K++  E +E 
Sbjct: 1200 EMNTLREKIGESGKALIEKEQEKAEARQSVKEKETLRQKVAELSQALL-EKQRNSEMIEQ 1258

Query: 931  EFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELID 990
            E N+  E      K   EK ++  E     E + Q  K + E L   V EL++  L    
Sbjct: 1259 EMNSLREKIGETGKAFIEKEQEKAE-----EGR-QSVKES-ETLRQKVAELSQALL---- 1307

Query: 991  KHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKL 1050
               QK++    +       +I +L   L +K++EI    Q+    ++   S+    + K 
Sbjct: 1308 ---QKERDVGQELV-SLREKIGELAQTLVKKEKEIKEGEQEKEEVKLKLTSLCQSLKEKE 1363

Query: 1051 AQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTE 1110
             +       ++   ++V +  L       EL    R+ + + +ELK+   +    + + +
Sbjct: 1364 TEVELTGTELKATREKVGELRLVLINKERELNEEKRQSECEKEELKQRVESLSQALVEKD 1423

Query: 1111 GMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQ 1169
              +I    E + + A                L++ + +E +QE+  LQ++  +   E Q
Sbjct: 1424 RALIEKE-EEVKEGAKQSKIEVEALRNQLVQLELAQAQE-MQEKGDLQDEKDRQAKEQQ 1480



 Score = 89.8 bits (213), Expect = 5e-16
 Identities = 194/1088 (17%), Positives = 434/1088 (39%), Gaps = 77/1088 (7%)

Query: 49   ERQIKFERAQKCLENAALVSKRIKEHRKATAELLGRPFVPGISESLANTLKQKEILMEKI 108
            ++  + +R    LE       + +EHR+   + L         + L+ TL + EI  E+I
Sbjct: 527  KKNSELQRENMALEQKVSELTQAEEHREKDIKFLQERL-----KELSQTLTENEIGTERI 581

Query: 109  KQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNALSVLQVK---- 164
            KQ+ E    +    V                 L  +  L   I+  + ALS  + +    
Sbjct: 582  KQHAEKDTSALKVRVSELSAALTMRDTKELETLEQIKSLKREIESCEMALSDKEKRAEDE 641

Query: 165  MKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQEN 224
             +  E  I  +++++ E  + I +K                         ++   K +  
Sbjct: 642  RRQSEKEISSVRQRVTELSEAIMSKEIQQEEREIEVRALKGRLEELEHALEESAEKSRVE 701

Query: 225  FIAMEAEWKDEKQRLL-KDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXX 283
                E +   ++  L  K ++ K+ R        ++L     E+S +     ++ E+   
Sbjct: 702  RQIREGDTLIQRAELFGKALKEKERRHMDDHREKEMLRQRVNELSQDIINKERDAEEELK 761

Query: 284  XXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNK 343
                          +  E   EE+   E +        T L + +E  E +  ++RQ   
Sbjct: 762  ALRRKTVELRQTLIEKEEDKAEEQRRSENEKEALRHKATGLLQALE-EERMAAEVRQGRL 820

Query: 344  ELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQD-TDKKI 402
            E+ ++      E +  +   +K    + +K       + +    +   E L Q   DK+ 
Sbjct: 821  EITSQAL---LEKEIETEKQEKERQTLDKKDREGETLQEEMAAVRRKREELGQALRDKEQ 877

Query: 403  NKNEI-AKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHME 461
             K E   + E   +SL+K + D    + EK+            ++  I Q ++   +  +
Sbjct: 878  EKCEADTQKEKENESLSKKVKDLSQALLEKE------------READILQEEVTAVRR-K 924

Query: 462  GPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDA 521
            G  L      T    E  K++++++ E   E   + V+ L + L   E +   L +E+ A
Sbjct: 925  GEEL----KQTLKDKEQDKIEKEVQNEKEREALSLKVEHLSQALLEKEREADTLQEEVTA 980

Query: 522  ANKNMIKVKSNHKLK-LKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGN 580
              +   ++K   K K  K+++K + N  +    ++++ +L++ L    ++   L+EE   
Sbjct: 981  VRRKGEELKQTLKDKEQKKIEKEVQNDKEKEALSQKVKQLSQALLEKEREADTLQEEVAA 1040

Query: 581  LQLHLVDY-DSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDE 639
            L+    +   + +  E +  +K ++ E   E + + +  L     +   E+ + + K ++
Sbjct: 1041 LRRKGEELKQTLKNKEQEHIEKEVQNEKEKEAQSQKVEHLSQALLEKESEVELTKGKKED 1100

Query: 640  VEDKLADISQLQ--------SDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQ 691
            +  ++ D+ Q Q         ++  S +K   L E +   +  ++E  L +++LK   + 
Sbjct: 1101 LTIQIRDLRQFQLENEKEIKEEERQSRLKVTELSETLINKTLQEEEKQLEVKSLK--GKT 1158

Query: 692  LYGTIKDLENDKEDIMNKLQNYIQENMDLTDKL--EKMSAEKISELLAKINHEEQSKIQT 749
            L   +K+ E +K++     Q   + +  L +K    +M  ++++ L  KI    ++ I+ 
Sbjct: 1159 LKLKVKECEEEKKERKKLNQKVSELSQALLEKQRNSEMIEQEMNTLREKIGESGKALIEK 1218

Query: 750  QFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEK 809
            +    A+ ++     E +  ++++    +   + +  ++E    SL  K  + G    EK
Sbjct: 1219 E-QEKAEARQSVKEKETLRQKVAELSQALLEKQRNSEMIEQEMNSLREKIGETGKAFIEK 1277

Query: 810  QKAYSE---YTIQEDELVNRLA-----VLMDHDRVVEKQLLEIEHENKEL-----QKKNQ 856
            ++  +E    +++E E + +        L+  +R V ++L+ +  +  EL     +K+ +
Sbjct: 1278 EQEKAEEGRQSVKESETLRQKVAELSQALLQKERDVGQELVSLREKIGELAQTLVKKEKE 1337

Query: 857  ILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQT 916
            I   E +  ++ L  +     +L EK    +L  +E    + ++ +L   L  I  E + 
Sbjct: 1338 IKEGEQEKEEVKLK-LTSLCQSLKEKETEVELTGTELKATREKVGEL--RLVLINKERE- 1393

Query: 917  LIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNM 976
             + ++K++ E  + E   ++ES     + L EK    IE   +++   ++ K  +E L  
Sbjct: 1394 -LNEEKRQSECEKEELKQRVESL---SQALVEKDRALIEKEEEVKEGAKQSKIEVEALRN 1449

Query: 977  NVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQ 1036
             + +L     + + +    Q  +     EQ I+E  K    L    E II +++ +   +
Sbjct: 1450 QLVQLELAQAQEMQEKGDLQDEKDRQAKEQQISESEKERMAL---GERIIEISRDLKRRE 1506

Query: 1037 VSYMSMVSDYESKLAQFTTKLENME--EEMQRVSKQLLDSK---QHNEELQILVREQDDQ 1091
            V  +    +  S     T + EN E  +  +R+  +L  ++   +H E  +I  RE+  +
Sbjct: 1507 VKQIKEEEESVSLQKIETLQKENKEGKQREERLKHRLRRTEMALRHTESEEIAWREKARE 1566

Query: 1092 IKELKETK 1099
            ++     K
Sbjct: 1567 LESKYRAK 1574



 Score = 81.8 bits (193), Expect = 1e-13
 Identities = 173/905 (19%), Positives = 364/905 (40%), Gaps = 76/905 (8%)

Query: 658  EIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQEN 717
            E +SVH   Q++      + +   +E     +  L   +  LE D      +L+   ++ 
Sbjct: 20   ESRSVHA--QLETTREELRSMRSQVETADEVERSLRSQVATLEQDIRSTRLQLETSKEDT 77

Query: 718  MDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSR 777
              +T +LE    E+ + L +++  EE++        + +I+     I+  E+ELS  +S 
Sbjct: 78   QSMTSRLEAQK-EEAAILRSQLEAEEETSQLKLKASEQEIKALRQQIQMSEAELSFVRSE 136

Query: 778  IC--RLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDR 835
            +    LE          Y +E K+ +L    QE + +     +QE E    LA    H  
Sbjct: 137  LAGSTLEAESLKSRLETYEMEAKS-RLEDKKQELRISQRIERLQESEKELALAREQLHSE 195

Query: 836  VVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTK 895
             +  ++ + +H+ +E +          ++L+  L+D+      L     + +L +   T+
Sbjct: 196  -LSAEIAKRQHQAQESE-------GAKESLEAELADVMGERERL-----QAELTQDSQTE 242

Query: 896  YQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIE 955
             +T L +L         EHQTL+   K+E+   E + N  ++   R+ + L E  ++  +
Sbjct: 243  KETALYNL---------EHQTLM---KQEL-SRETQLNLTVQEREREIRSLKENIQR-AQ 288

Query: 956  YVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDY---TEQYINEIN 1012
               +   Q++E + + E   M  EE +++ L    + + K +    ++    E  + EI 
Sbjct: 289  QENEAAEQIRECEKDRETA-MKAEESSRITLSEKGREISKMKESEKEHQFKMENALKEIE 347

Query: 1013 KLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKL--AQFTTKLENMEEEMQRVSKQ 1070
                +L++KD  +  L Q++   +   M+ +   +  L   +    ++ ++E +QR    
Sbjct: 348  SQTIILREKDTFLETLKQRLKECEEEIMNELQRQKHMLIVEERERDIKILQESVQREK-- 405

Query: 1071 LLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDX 1130
              D  +H  +     RE  ++ KE    +    +   + +  I+  +++   D   ++  
Sbjct: 406  --DMVKHISDQWESQRESSERQKESTLIQHRLIVEERERDIKILQESVQRERDMVKHISD 463

Query: 1131 XXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDV 1190
                        K  +  E  Q  S  +E+ A+L     +  + ++Q E L++ LT H +
Sbjct: 464  QWESQRESAERQKENKISELSQALS-KKEREAELLERQTKRDSDLLQ-EQLDS-LTQH-L 519

Query: 1191 VNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADF 1250
              +E  ++  S+L++ N   +  +S + +        +      + EL  Q L + E   
Sbjct: 520  EEKEIAHKKNSELQRENMALEQKVSELTQAEEHREKDIKFLQERLKEL-SQTLTENEIGT 578

Query: 1251 QKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQ 1310
            ++ +       SA + +  +L  ++   T  +T ++ T+EQ+ SL+ +++  E  L + +
Sbjct: 579  ERIKQHAEKDTSALKVRVSELSAAL---TMRDTKELETLEQIKSLKREIESCEMALSDKE 635

Query: 1311 EKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQ---EQSI 1367
            ++  D   Q E   S +                       ++R      ++++   E+S 
Sbjct: 636  KRAEDERRQSEKEISSVRQRVTELSEAIMSKEIQQEEREIEVRALKGRLEELEHALEESA 695

Query: 1368 ------LNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTH 1421
                    I E +  ++++              ++D   K + L  ++     +I  K  
Sbjct: 696  EKSRVERQIREGDTLIQRAELFGKALKEKERRHMDDHREKEM-LRQRVNELSQDIINKER 754

Query: 1422 EYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLK-------MHENANHYE 1474
            +    L     +   +RQ L+E E+   +     E+E   LR K       + E     E
Sbjct: 755  DAEEELKALRRKTVELRQTLIEKEEDKAEEQRRSENEKEALRHKATGLLQALEEERMAAE 814

Query: 1475 TMQKESEIERVKLIE---ELNVKITESVSLNKQVAELNKALEEEVA----KTNEMQTALE 1527
              Q   EI    L+E   E   +  E  +L+K+  E  + L+EE+A    K  E+  AL 
Sbjct: 815  VRQGRLEITSQALLEKEIETEKQEKERQTLDKKDRE-GETLQEEMAAVRRKREELGQALR 873

Query: 1528 NQEIE 1532
            ++E E
Sbjct: 874  DKEQE 878



 Score = 67.7 bits (158), Expect = 2e-09
 Identities = 142/831 (17%), Positives = 327/831 (39%), Gaps = 58/831 (6%)

Query: 766  NIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVN 825
            ++ ++L   +  +  +   +   ++   SL  +   L   ++  +            + +
Sbjct: 23   SVHAQLETTREELRSMRSQVETADEVERSLRSQVATLEQDIRSTRLQLETSKEDTQSMTS 82

Query: 826  RLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANR 885
            RL    +   ++  QL E E E  +L+ K      +    QI +S+ +  +    E A  
Sbjct: 83   RLEAQKEEAAILRSQL-EAEEETSQLKLKASEQEIKALRQQIQMSEAELSF-VRSELAGS 140

Query: 886  TDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEF---NTQIESAIRD 942
            T   E+ES K + +  ++E+  +    + +  I Q+ + +++ E E      Q+ S +  
Sbjct: 141  T--LEAESLKSRLETYEMEAKSRLEDKKQELRISQRIERLQESEKELALAREQLHSELSA 198

Query: 943  KKVLNEKYEKNIEYVTQ-LEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSP 1001
            +    +   +  E   + LEA+L +     E L   + + ++   E    +++ Q     
Sbjct: 199  EIAKRQHQAQESEGAKESLEAELADVMGERERLQAELTQDSQTEKETALYNLEHQTLM-- 256

Query: 1002 DYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVS------YMSMVSDYESKLAQFTT 1055
               +Q ++   +LN  +++++ EI +L + I  AQ              D E+ +    +
Sbjct: 257  ---KQELSRETQLNLTVQEREREIRSLKENIQRAQQENEAAEQIRECEKDRETAMKAEES 313

Query: 1056 KLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIIS 1115
                + E+ + +SK     K+H  +++  ++E + Q   L+E K TF   + +       
Sbjct: 314  SRITLSEKGREISKMKESEKEHQFKMENALKEIESQTIILRE-KDTFLETLKQRLKECEE 372

Query: 1116 STIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKI 1175
              +  +    + +               VQ E++ ++  S  Q +S + ++E Q+     
Sbjct: 373  EIMNELQRQKHMLIVEERERDIKILQESVQREKDMVKHISD-QWESQRESSERQK----- 426

Query: 1176 IQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEI 1235
                   + L  H ++ +E+   +K   E +  E D +     +  S   SA  Q+  +I
Sbjct: 427  ------ESTLIQHRLIVEERERDIKILQESVQRERDMVKHISDQWESQRESAERQKENKI 480

Query: 1236 AELWKQHLAQREADFQKTEHE-------LRVQLSAFESKYEQLLDSVQSSTQEETNKIVT 1288
            +EL  Q L+++E + +  E +       L+ QL +     E+   + + +++ +   +  
Sbjct: 481  SEL-SQALSKKEREAELLERQTKRDSDLLQEQLDSLTQHLEEKEIAHKKNSELQRENMAL 539

Query: 1289 MEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXX 1348
             ++V+ L    + +E+ ++ LQE+  ++     +  +EI  E++                
Sbjct: 540  EQKVSELTQAEEHREKDIKFLQERLKELSQ--TLTENEIGTERIKQHAEKDTSALKVRVS 597

Query: 1349 XXDLRTENQSYKQMQE-QSILNINEE----NAQLKKSSXXXXXXXXXXXXRVNDAEAKVL 1403
                    +  K+++  + I ++  E       L                 ++    +V 
Sbjct: 598  ELSAALTMRDTKELETLEQIKSLKREIESCEMALSDKEKRAEDERRQSEKEISSVRQRVT 657

Query: 1404 ELTHQLELKDSEIYQKTHEYTI-TLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAIL 1462
            EL+  +  K  EI Q+  E  +  L  R +E E+  ++  E + R+E     +E +  I 
Sbjct: 658  ELSEAIMSK--EIQQEEREIEVRALKGRLEELEHALEESAE-KSRVE--RQIREGDTLIQ 712

Query: 1463 RLKMHENA-NHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNE 1521
            R ++   A    E    +   E+  L + +N    + ++  +   E  KAL  +  +   
Sbjct: 713  RAELFGKALKEKERRHMDDHREKEMLRQRVNELSQDIINKERDAEEELKALRRKTVELR- 771

Query: 1522 MQTALENQEIEIVTLNDEITNLQNMVRASSSKIQ--KHVSFASDTKQGRDE 1570
             QT +E +E +           + +   ++  +Q  +    A++ +QGR E
Sbjct: 772  -QTLIEKEEDKAEEQRRSENEKEALRHKATGLLQALEEERMAAEVRQGRLE 821



 Score = 52.8 bits (121), Expect = 8e-05
 Identities = 109/529 (20%), Positives = 215/529 (40%), Gaps = 60/529 (11%)

Query: 1108 KTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTE 1167
            K +   I S  E   +++ +V             ++ Q E     ERS L+ Q A L  +
Sbjct: 4    KRKSYHIRSKHETAKEESRSVHAQLETTREELRSMRSQVETADEVERS-LRSQVATLEQD 62

Query: 1168 LQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLE-QLNTENDNLLSTVAE---LRSS 1223
            ++    ++   +     +T      +E+   L+S+LE +  T    L ++  E   LR  
Sbjct: 63   IRSTRLQLETSKEDTQSMTSRLEAQKEEAAILRSQLEAEEETSQLKLKASEQEIKALRQQ 122

Query: 1224 ISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEET 1283
            I  +  +  F  +EL    L       +   +E+  + S  E K ++L  S +    +E+
Sbjct: 123  IQMSEAELSFVRSELAGSTLEAESLKSRLETYEMEAK-SRLEDKKQELRISQRIERLQES 181

Query: 1284 NKIVTME----------QVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVA 1333
             K + +           ++   Q++ Q+ E    +L+ + ADV+ + E L++E+  +   
Sbjct: 182  EKELALAREQLHSELSAEIAKRQHQAQESEGAKESLEAELADVMGERERLQAELTQDSQT 241

Query: 1334 FXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXX 1393
                             +L  E Q    +QE+       E   LK++             
Sbjct: 242  EKETALYNLEHQTLMKQELSRETQLNLTVQERE-----REIRSLKEN--------IQRAQ 288

Query: 1394 RVNDAEAKVLELTHQLELKDSEIYQKTHEYT-ITLTQRNDEFENVRQQLVEYEKRIEDLT 1452
            + N+A  ++ E       KD E   K  E + ITL+++  E   +++   E++ ++E+  
Sbjct: 289  QENEAAEQIRECE-----KDRETAMKAEESSRITLSEKGREISKMKESEKEHQFKMENAL 343

Query: 1453 YEKESELAILRLK---MHENANHYETMQKE--SEIERVK---LIE--ELNVKI-TESVSL 1501
             E ES+  ILR K   +       +  ++E  +E++R K   ++E  E ++KI  ESV  
Sbjct: 344  KEIESQTIILREKDTFLETLKQRLKECEEEIMNELQRQKHMLIVEERERDIKILQESVQR 403

Query: 1502 NKQVAELNKALEEEVAKTNEMQ---------TALENQEIEIVTLNDEITNLQNMVRASSS 1552
             K + +      E   +++E Q           +E +E +I  L + +   ++MV+  S 
Sbjct: 404  EKDMVKHISDQWESQRESSERQKESTLIQHRLIVEERERDIKILQESVQRERDMVKHISD 463

Query: 1553 KIQKHVSFASDTKQGRDEQLDNTMNK-----ELLDAVPRAELDLAMYML 1596
            + +     A   K+ +  +L   ++K     ELL+   + + DL    L
Sbjct: 464  QWESQRESAERQKENKISELSQALSKKEREAELLERQTKRDSDLLQEQL 512


>UniRef50_A0D4Y2 Cluster: Chromosome undetermined scaffold_38, whole
            genome shotgun sequence; n=1; Paramecium tetraurelia|Rep:
            Chromosome undetermined scaffold_38, whole genome shotgun
            sequence - Paramecium tetraurelia
          Length = 1239

 Score =  129 bits (311), Expect = 7e-28
 Identities = 213/966 (22%), Positives = 431/966 (44%), Gaps = 116/966 (12%)

Query: 396  QDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLE 455
            Q  D  I+ NE   L  +IQ  N++L D   ++ ++             +  LI  L  +
Sbjct: 276  QIIDFPISSNEY--LTQIIQEQNEELSDMTELLEQQQQEIQNKDLYVQQQQLLINDLLRK 333

Query: 456  HQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQ-ELNDEIKDVNVKDLIEKLKSAEEQITQ 514
             ++ +   +       ++   E    Q+ +KQ + N + +D+ +K+L ++ +  + Q+  
Sbjct: 334  LEEFVNCTNAFKKQLESQG-EEKKNYQQYIKQLDFNIKQQDLQIKNLQKEKEVYKRQVQS 392

Query: 515  LNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAEL 574
            L  + D   K   K++  +   ++ M   ++  S++  +++E   L +    L   +   
Sbjct: 393  LQRDKDMYIKQNEKLRRQYDEDIQMMNSQLEQ-SQLLINDQECAELRQIKDQLQFDLEIA 451

Query: 575  EEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLV-QELHIL 633
            + E  NL+  LV   S  +     +   +E+  + ET+L   +L  S + +   Q+L   
Sbjct: 452  KSEIQNLK-QLVYEISTEINVGFKFLGSLEVRQI-ETKLDIQTLCHSYRREYQKQKLQKE 509

Query: 634  QQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDA----LSASKKELAL--------- 680
            Q     ++D  A I Q+   +   E      E+QI+     + +SKKE+AL         
Sbjct: 510  QGHLSILQDYKAQIFQINLQKSSLESIVAQQEKQINNYINDVVSSKKEIALICQEYEQKI 569

Query: 681  ---------VIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEK 731
                     V+  LK  ++QL+ T   L N +++  ++L+N I E+ + T  LEK     
Sbjct: 570  AEVNDQKSVVLNELKQCEDQLFQTNLQLINQQQEFQSQLRNKILEHNEQTTDLEKSL--- 626

Query: 732  ISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDR 791
                       +QSKI+ +F +  +I ++       E E+ KY      L+E I  ++  
Sbjct: 627  -----------QQSKIEHEF-LKKQIHDK-------EKEIEKYSLNSKELQEQIIRLDQE 667

Query: 792  RYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKEL 851
            + +L+         ++ ++K   +   Q D+  +++  L      + +QL +  +  +E 
Sbjct: 668  KKTLQHSIQNSDKLIELEKKQLEQ---QRDQNQHKILELQTQVEQITEQLSQQMNLFEEQ 724

Query: 852  QKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRIT 911
            Q++NQ L+E+ +  Q      +Q Y+ ++++       E   TK Q     L++ +++  
Sbjct: 725  QQENQNLIEQIEKYQ----QKEQEYDFILQQQE-----ELSQTKQQ-----LQNQIQQ-- 768

Query: 912  HEHQTLIVQK-KKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNN 970
            HE+Q  IVQ    E++        Q +S  ++  +LN++   +   V QL+   Q+++N 
Sbjct: 769  HENQLQIVQNLYDELKISHENSKHQNDSLQQEIDLLNQQLLDSKNEVEQLKQMQQQFENL 828

Query: 971  IENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEI--IAL 1028
            I  LN  +EE N+ N    D    +QQ Q   + +  +N+IN+L   +++  E I  I  
Sbjct: 829  ILQLNEQIEEQNQ-NQNQTD---LQQQLQEEIHNK--VNQINQLTEQIEELTENIRQIKD 882

Query: 1029 NQKINNAQVSYMSMV--SDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVR 1086
            N  +  AQ+     +  +  +  + Q  T L N++ +    S++L + +Q+ +      R
Sbjct: 883  NNAVEIAQIQQQHTIELNGKKEVIIQLETSLHNLQHQNSVNSQELANLQQYAQN----ER 938

Query: 1087 EQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQ- 1145
             Q  Q  E+++ +L  ++     E + ++S I  +S    +              ++ + 
Sbjct: 939  SQQQQETEIEKQQLKLQITSFNEERVTLNSQITQLSQQVEHYSNLNSQLTQKIEEIQQKL 998

Query: 1146 EEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQ 1205
             +++  Q+ S   +Q    N E QE      Q+  L  EL    VV QE+ +Q ++  E+
Sbjct: 999  SDQQSQQQPSNKVDQQEYRNLE-QENQDLTDQISKLLEEL---GVVEQER-SQKEADNEE 1053

Query: 1206 LNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFE 1265
            L  + +  L+T+AELRS        + +++++L + H       FQ  + E    L    
Sbjct: 1054 LKIQYEQALNTIAELRS--------KEYDVSQLKQSH-----NQFQTLQDE-NTNLKQLY 1099

Query: 1266 SKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRS 1325
            ++  +L+D +    QE+       EQ   + N LQ+++E+ + L+ KY ++I + + L S
Sbjct: 1100 AQKLKLVDQLNKQIQEQ-------EQ--QMNNYLQNEQEY-QKLKVKYQELIIEKDQLSS 1149

Query: 1326 EIEDEK 1331
            +IE ++
Sbjct: 1150 QIEKQQ 1155



 Score =  120 bits (290), Expect = 3e-25
 Identities = 216/1120 (19%), Positives = 466/1120 (41%), Gaps = 97/1120 (8%)

Query: 487  QELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKT-ID 545
            Q  N++  +   +D  ++L+   EQ  QL     +  +N    ++N ++ + Q +   I 
Sbjct: 107  QTNNNQTLNQQQQDQPKQLEKQPEQEKQLEQNESSQQRN---TQNNPQIAVSQPKANQIS 163

Query: 546  NFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEM 605
            N  ++  SN  +    ++L  L Q+V +L  E   L   L +        + +       
Sbjct: 164  NQPEIQQSNHHVNN--QQLVVLQQQVLQLATENKELSSQLQELCKAY---NQLILNYDSC 218

Query: 606  ENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLE 665
             N  +T  KA+ L ++   +L Q +  L  K  + ++   D+ Q   + + ++       
Sbjct: 219  NNFIQTLPKAL-LPQNYMDNLDQNMKYL--KLFQPQNISLDLQQFNLNLLKNQTHVFVPP 275

Query: 666  EQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENM----DLT 721
            + ID   +S + L  +I+      E+L    + LE  +++I NK   Y+Q+      DL 
Sbjct: 276  QIIDFPISSNEYLTQIIQE---QNEELSDMTELLEQQQQEIQNK-DLYVQQQQLLINDLL 331

Query: 722  DKLEKM--SAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRIC 779
             KLE+         + L     E+++  Q    +D  I+++DL I+N++ E   YK ++ 
Sbjct: 332  RKLEEFVNCTNAFKKQLESQGEEKKNYQQYIKQLDFNIKQQDLQIKNLQKEKEVYKRQVQ 391

Query: 780  RLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEK 839
             L+    +   +   L R+ D+    +   Q   S+  I + E            R ++ 
Sbjct: 392  SLQRDKDMYIKQNEKLRRQYDE-DIQMMNSQLEQSQLLINDQECAEL--------RQIKD 442

Query: 840  QL-LEIEHENKELQKKNQILLEENQNLQISLSDM-QQHYNALVEKANRTDLAESESTKYQ 897
            QL  ++E    E+Q   Q++ E +  + +    +       +  K +   L  S   +YQ
Sbjct: 443  QLQFDLEIAKSEIQNLKQLVYEISTEINVGFKFLGSLEVRQIETKLDIQTLCHSYRREYQ 502

Query: 898  TQLRDLESNLKRITHEHQTLIVQ---KKKEIEDL----EIEFNTQIESAIRDKK---VLN 947
             Q    E     I  +++  I Q   +K  +E +    E + N  I   +  KK   ++ 
Sbjct: 503  KQKLQKEQGHLSILQDYKAQIFQINLQKSSLESIVAQQEKQINNYINDVVSSKKEIALIC 562

Query: 948  EKYEKNIEYVTQLEAQL---------QEYKNNIENLNMNVEELNKMNLELIDKH-----V 993
            ++YE+ I  V   ++ +         Q ++ N++ +N   E  +++  ++++ +     +
Sbjct: 563  QEYEQKIAEVNDQKSVVLNELKQCEDQLFQTNLQLINQQQEFQSQLRNKILEHNEQTTDL 622

Query: 994  QKQQTQSP---DYTEQYIN----EINKLNALLKQKDEEIIALNQKINNAQVSYMSM---- 1042
            +K   QS    ++ ++ I+    EI K +   K+  E+II L+Q+    Q S  +     
Sbjct: 623  EKSLQQSKIEHEFLKKQIHDKEKEIEKYSLNSKELQEQIIRLDQEKKTLQHSIQNSDKLI 682

Query: 1043 ---VSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETK 1099
                   E +  Q   K+  ++ +++++++QL       EE Q   +   +QI++ ++ +
Sbjct: 683  ELEKKQLEQQRDQNQHKILELQTQVEQITEQLSQQMNLFEEQQQENQNLIEQIEKYQQKE 742

Query: 1100 LTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQE 1159
              ++  + + E   +S T + + +     +            LK+  E    Q  S LQ+
Sbjct: 743  QEYDFILQQQEE--LSQTKQQLQNQIQQHENQLQIVQNLYDELKISHENSKHQNDS-LQQ 799

Query: 1160 QSAKLNTELQECYTKIIQLETL-----NTELTGHDVVNQEQINQLKSKL-EQLNTENDN- 1212
            +   LN +L +   ++ QL+ +     N  L  ++ + ++  NQ ++ L +QL  E  N 
Sbjct: 800  EIDLLNQQLLDSKNEVEQLKQMQQQFENLILQLNEQIEEQNQNQNQTDLQQQLQEEIHNK 859

Query: 1213 ------LLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFES 1266
                  L   + EL  +I    D    EIA++ +QH  +      K E  ++++ S    
Sbjct: 860  VNQINQLTEQIEELTENIRQIKDNNAVEIAQIQQQHTIELNG---KKEVIIQLETSLHNL 916

Query: 1267 KYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSE 1326
            +++  ++S + +  ++  +    +Q    + + Q  +  + +  E+   + +QI  L  +
Sbjct: 917  QHQNSVNSQELANLQQYAQNERSQQQQETEIEKQQLKLQITSFNEERVTLNSQITQLSQQ 976

Query: 1327 IEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXX 1386
            +E                      D +++ Q   ++ +Q   N+ +EN  L         
Sbjct: 977  VEHYS-NLNSQLTQKIEEIQQKLSDQQSQQQPSNKVDQQEYRNLEQENQDLTDQISKLLE 1035

Query: 1387 XXXXXXXRVNDAEAKVLELTHQLELKDSEIYQ-KTHEYTIT-LTQRNDEFENVRQQLVEY 1444
                     +  EA   EL  Q E   + I + ++ EY ++ L Q +++F+ ++ +    
Sbjct: 1036 ELGVVEQERSQKEADNEELKIQYEQALNTIAELRSKEYDVSQLKQSHNQFQTLQDENTNL 1095

Query: 1445 EKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKL-IEELNVKITESVSLNK 1503
             K++     +   +L     +  +  N+Y  +Q E E +++K+  +EL ++  +  S  +
Sbjct: 1096 -KQLYAQKLKLVDQLNKQIQEQEQQMNNY--LQNEQEYQKLKVKYQELIIEKDQLSSQIE 1152

Query: 1504 QVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNL 1543
            +  + +  +E+      E    L+  E EI  LN +I  L
Sbjct: 1153 KQQQTSSKIEDTKEFIVEQNLKLQRMEQEIAGLNSKILQL 1192



 Score = 94.3 bits (224), Expect = 2e-17
 Identities = 141/808 (17%), Positives = 345/808 (42%), Gaps = 83/808 (10%)

Query: 815  EYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQ 874
            ++ I  +E + +  ++ + +  +      +E + +E+Q K+  + ++   +   L  +++
Sbjct: 279  DFPISSNEYLTQ--IIQEQNEELSDMTELLEQQQQEIQNKDLYVQQQQLLINDLLRKLEE 336

Query: 875  HYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIE-FN 933
              N       + +    E   YQ  ++ L+ N+K+   + Q   +QK+KE+   +++   
Sbjct: 337  FVNCTNAFKKQLESQGEEKKNYQQYIKQLDFNIKQ--QDLQIKNLQKEKEVYKRQVQSLQ 394

Query: 934  TQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMN-VEELNKMNLELIDKH 992
               +  I+  + L  +Y+++I+ +     Q Q   N+ E   +  +++  + +LE+    
Sbjct: 395  RDKDMYIKQNEKLRRQYDEDIQMMNSQLEQSQLLINDQECAELRQIKDQLQFDLEIAKSE 454

Query: 993  VQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALN------------QKINNAQVSYM 1040
            +Q  +    + + +       L +L  ++ E  + +             QK+   Q  ++
Sbjct: 455  IQNLKQLVYEISTEINVGFKFLGSLEVRQIETKLDIQTLCHSYRREYQKQKLQKEQ-GHL 513

Query: 1041 SMVSDYESKLAQFTTKLENME----EEMQRVSKQLLDSKQHNEELQILVREQDDQIKELK 1096
            S++ DY++++ Q   +  ++E    ++ ++++  + D     +E+ ++ +E + +I E+ 
Sbjct: 514  SILQDYKAQIFQINLQKSSLESIVAQQEKQINNYINDVVSSKKEIALICQEYEQKIAEVN 573

Query: 1097 ETKLTFEMNIPKTEGMIISSTIEPMSDDA-------NNVDXXXXXXXXXXXXLKVQE-EE 1148
            + K      + + E  +  + ++ ++          N +             L+  + E 
Sbjct: 574  DQKSVVLNELKQCEDQLFQTNLQLINQQQEFQSQLRNKILEHNEQTTDLEKSLQQSKIEH 633

Query: 1149 EFIQERSVLQEQSA-KLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLN 1207
            EF++++   +E+   K +   +E   +II+L+     L  H + N +++ +L+ K  QL 
Sbjct: 634  EFLKKQIHDKEKEIEKYSLNSKELQEQIIRLDQEKKTLQ-HSIQNSDKLIELEKK--QLE 690

Query: 1208 TENDNLLSTVAELRSSISSAVDQRG-----FEIAELWKQHLAQREADFQKTEHELRVQLS 1262
             + D     + EL++ +    +Q       FE  +   Q+L ++   +Q+ E E    L 
Sbjct: 691  QQRDQNQHKILELQTQVEQITEQLSQQMNLFEEQQQENQNLIEQIEKYQQKEQEYDFILQ 750

Query: 1263 AFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEI 1322
              E +  Q    +Q+  Q+  N++  ++ +        +  +H  +  ++  D++NQ ++
Sbjct: 751  QQE-ELSQTKQQLQNQIQQHENQLQIVQNLYDELKISHENSKHQNDSLQQEIDLLNQ-QL 808

Query: 1323 LRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSX 1382
            L S+ E E++                  + + +NQ+   +Q+Q    I+ +  Q      
Sbjct: 809  LDSKNEVEQLKQMQQQFENLILQLNEQIEEQNQNQNQTDLQQQLQEEIHNKVNQ------ 862

Query: 1383 XXXXXXXXXXXRVNDAEAKVLELTHQL-ELKDS---EIYQKTHEYTITLTQRNDEFENVR 1438
                        +N    ++ ELT  + ++KD+   EI Q   ++TI L  +       +
Sbjct: 863  ------------INQLTEQIEELTENIRQIKDNNAVEIAQIQQQHTIELNGK-------K 903

Query: 1439 QQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITES 1498
            + +++ E  + +L ++       L        N     Q+E+EIE+ +L  ++     E 
Sbjct: 904  EVIIQLETSLHNLQHQNSVNSQELANLQQYAQNERSQQQQETEIEKQQLKLQITSFNEER 963

Query: 1499 VSLNKQVAELNKALE-------EEVAKTNEMQTALENQEIEIVTLN----DEITNLQNMV 1547
            V+LN Q+ +L++ +E       +   K  E+Q  L +Q+ +    N     E  NL+   
Sbjct: 964  VTLNSQITQLSQQVEHYSNLNSQLTQKIEEIQQKLSDQQSQQQPSNKVDQQEYRNLEQEN 1023

Query: 1548 RASSSKIQKHVSFASDTKQGRDE-QLDN 1574
            +  + +I K +      +Q R + + DN
Sbjct: 1024 QDLTDQISKLLEELGVVEQERSQKEADN 1051



 Score = 86.2 bits (204), Expect = 7e-15
 Identities = 92/415 (22%), Positives = 205/415 (49%), Gaps = 39/415 (9%)

Query: 446  DTLIAQLQLEHQQHMEGPSLIHVGTNTEDV--NEIAKVQEQLKQELNDEIKDVNVKDLIE 503
            D+L  ++ L +QQ ++  + +      +    N I ++ EQ++++  ++ +    + L E
Sbjct: 795  DSLQQEIDLLNQQLLDSKNEVEQLKQMQQQFENLILQLNEQIEEQNQNQNQTDLQQQLQE 854

Query: 504  KLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEE 563
            ++ +   QI QL ++I+   +N+ ++K N+ +++ Q+Q+   +  +++   + I++L   
Sbjct: 855  EIHNKVNQINQLTEQIEELTENIRQIKDNNAVEIAQIQQ--QHTIELNGKKEVIIQLETS 912

Query: 564  LHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEME--NLAETRLKAISLLE- 620
            LH+L  + +   +E  NLQ +  +  S +  E+++ K+ ++++  +  E R+   S +  
Sbjct: 913  LHNLQHQNSVNSQELANLQQYAQNERSQQQQETEIEKQQLKLQITSFNEERVTLNSQITQ 972

Query: 621  -SQKFDLVQELHI-LQQKYDEVEDKLAD-ISQLQSDQVCSEIKSVHLEEQ----IDALSA 673
             SQ+ +    L+  L QK +E++ KL+D  SQ Q      + +  +LE++     D +S 
Sbjct: 973  LSQQVEHYSNLNSQLTQKIEEIQQKLSDQQSQQQPSNKVDQQEYRNLEQENQDLTDQISK 1032

Query: 674  SKKELALV----------IENLKLDKEQLYGTIKDLENDKEDI--MNKLQNYIQENMDLT 721
              +EL +V           E LK+  EQ   TI +L + + D+  + +  N  Q   D  
Sbjct: 1033 LLEELGVVEQERSQKEADNEELKIQYEQALNTIAELRSKEYDVSQLKQSHNQFQTLQDEN 1092

Query: 722  DKLEKMSAEK---ISELLAKINHEEQ---SKIQTQFGID-AKIQERDLYIE--NIESELS 772
              L+++ A+K   + +L  +I  +EQ   + +Q +      K++ ++L IE   + S++ 
Sbjct: 1093 TNLKQLYAQKLKLVDQLNKQIQEQEQQMNNYLQNEQEYQKLKVKYQELIIEKDQLSSQIE 1152

Query: 773  KYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRL 827
            K +    ++E++   + ++   L+R   ++   L  K     + T Q DE   +L
Sbjct: 1153 KQQQTSSKIEDTKEFIVEQNLKLQRMEQEIAG-LNSK---ILQLTAQRDEYKEQL 1203



 Score = 47.6 bits (108), Expect = 0.003
 Identities = 86/453 (18%), Positives = 194/453 (42%), Gaps = 52/453 (11%)

Query: 143  DVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXX 202
            ++  L+  + +  N +  L+   +  E  IL L E+I E++Q     N+  T        
Sbjct: 800  EIDLLNQQLLDSKNEVEQLKQMQQQFENLILQLNEQIEEQNQ-----NQNQTDLQQQLQE 854

Query: 203  XXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKD-VRISSLEEANKLLE 261
                         +Q+ ++ EN      + KD     +  I+ +  + ++  +E    LE
Sbjct: 855  EIHNKVNQINQLTEQIEELTENI----RQIKDNNAVEIAQIQQQHTIELNGKKEVIIQLE 910

Query: 262  AARFEISLEHSKLAQEL---EQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEI 318
             +   +  ++S  +QEL   +Q              + KQ ++       E  E+ +L  
Sbjct: 911  TSLHNLQHQNSVNSQELANLQQYAQNERSQQQQETEIEKQQLKLQITSFNE--ERVTLN- 967

Query: 319  ANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNT 378
            + +T+L++++E   +LN Q+ Q  +E++ KL    ++ ++   PS K    + ++  RN 
Sbjct: 968  SQITQLSQQVEHYSNLNSQLTQKIEEIQQKL----SDQQSQQQPSNK----VDQQEYRNL 1019

Query: 379  ASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXX 438
                         E  NQD   +I+K  + +L +V Q  ++   D E +  + +      
Sbjct: 1020 -------------EQENQDLTDQISK-LLEELGVVEQERSQKEADNEELKIQYE-QALNT 1064

Query: 439  XXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDV-NEIAKVQEQLKQELNDEIKDVN 497
                  K+  ++QL+  H Q     +L    TN + +  +  K+ +QL +++ ++ + +N
Sbjct: 1065 IAELRSKEYDVSQLKQSHNQFQ---TLQDENTNLKQLYAQKLKLVDQLNKQIQEQEQQMN 1121

Query: 498  ----VKDLIEKLKSAEEQI----TQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSK 549
                 +   +KLK   +++     QL+ +I+   +   K++   +  ++Q  K      +
Sbjct: 1122 NYLQNEQEYQKLKVKYQELIIEKDQLSSQIEKQQQTSSKIEDTKEFIVEQNLKLQRMEQE 1181

Query: 550  VSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQ 582
            ++  N +I++LT +     +++ E +++  N Q
Sbjct: 1182 IAGLNSKILQLTAQRDEYKEQL-EFKQKNANSQ 1213


>UniRef50_Q23E34 Cluster: Putative uncharacterized protein; n=2;
            Tetrahymena thermophila SB210|Rep: Putative
            uncharacterized protein - Tetrahymena thermophila SB210
          Length = 3482

 Score =  128 bits (310), Expect = 9e-28
 Identities = 207/1056 (19%), Positives = 446/1056 (42%), Gaps = 106/1056 (10%)

Query: 337  QIRQTNKELENKLATMGTESKAVSSPSKKGSP-------LISRKSGRNTASKMKSPWSQL 389
            Q +Q+N++ +N+L +  T   A S+P+   +        +ISR        + ++     
Sbjct: 2446 QFQQSNQQNQNQLESSRTLRSASSNPNIAANTQPIQLQYVISRNQLNQPQQQQQANIIPD 2505

Query: 390  SSETLNQDTDK-KINKNEIAKLEMVIQSLNKDLVD--KEYVISEKDTXXXXXXXXXXG-- 444
            +S+ +NQ  +K +I +N I++L+ + +++ K +    ++ +  E+++          G  
Sbjct: 2506 NSKQINQQVNKNQILRNSISQLKNIDENIQKQIKSNVEDKMQQEQNSSLHSETFSLNGTF 2565

Query: 445  --KDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQL------KQELNDEIKDV 496
                 ++ +  L++  +    +     ++ + + E+   + QL      KQ   D++K  
Sbjct: 2566 DQTREILKERNLQNMINTASKNFSKAQSHEQKIIELQTDRSQLLKMIATKQLEIDDLKQK 2625

Query: 497  NVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKE 556
            N ++ I  L    +++ + N++++  N+ + +       ++ Q  K +  ++ +++ N+ 
Sbjct: 2626 NNQEAI--LIQRIDKLVEENEQLNFQNQKLAQDYQQLNERVNQNLKYMKEYNLLNEENQS 2683

Query: 557  IVRLTEELHHLSQKV---AELEEEKGNLQLHLVDYDSGRMIE---------SDVYKKMIE 604
            +   TEE   L  K+     +   + N  L +++ +    IE         S     M +
Sbjct: 2684 LCEKTEEYQELLDKLEIKITILSNENNTLLKMME-EKQEQIELLKQREEEHSQSQNSMTK 2742

Query: 605  MENLAETRLKAISLLESQKFDLVQELHILQ-----QKYDEVEDKLAD------------I 647
             ++L E + + I  LE Q  +  ++  +L      Q+    EDKL +            I
Sbjct: 2743 FQDLLEKKNQLIKQLEKQLREAQEQNKVLNNEIIFQQEQFTEDKLNEAVSNIVSEKNTLI 2802

Query: 648  SQLQSDQVCSEIKSVHLEEQIDALS---ASKKELALVIENLKLDKEQLYGTIKDLENDKE 704
             Q+ ++    +IK   L E+  +L    A +  +    + LK  KE +      +  D++
Sbjct: 2803 EQISAENSNFKIKIKSLLEENKSLQEKVAKQNAIEWYADQLKTTKETI--EENQMIKDRQ 2860

Query: 705  DIMNK-LQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKI-QTQFGIDAKIQERDL 762
             I NK L   +++ +DL  +  ++   KI +L    + E+++ + +T+  I+ K++E   
Sbjct: 2861 LIENKELIQEMKKIIDLNKEQLELKENKILQLKQTYDKEKEAILRETEHQINEKLEEIKA 2920

Query: 763  YIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYL--QEKQKAYSEYTIQE 820
            Y   IE    K++  +   ++ +  ME++  + +   DQ   Y+  QE QK   E  I  
Sbjct: 2921 YTLEIE----KFRDELVLTKKQL--MEEKNRA-DYFQDQFKIYMGNQEHQKFQQEQIIMN 2973

Query: 821  DELVNRLAVLMDHDRV-VEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQH-YNA 878
              L N+ +     D++    ++ +++++N  +  K   ++  N NL   L +  Q     
Sbjct: 2974 TCLENKRS---QQDKIHFLNEIEDLKNKNIAVTDKLDQMIAVNDNLTEVLKEKSQEIQEL 3030

Query: 879  LVEKANRTDLAESES---TKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQ 935
            L+EK       E E     + Q  L  LE   +    E Q +   K+K        +  Q
Sbjct: 3031 LIEKDKLLYEREQEQIQLERIQNNLHQLEEERENFLKETQDVYELKEKVSHQETNRYKQQ 3090

Query: 936  IES---AIRDKKV-LNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDK 991
            IE     I+ K+   NE+++KN+  + Q + ++ + K+ I  LN  + ++   +   I +
Sbjct: 3091 IEDLKLQIQQKEFETNEQFQKNLNQLEQSQQEIIQLKDQINKLNYQISQIQSEDRLKIQE 3150

Query: 992  HVQ------KQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSD 1045
             V       + Q  + D   +  N  +KL  L  Q+D+    L+++     + +     +
Sbjct: 3151 RVHFDSTLLELQKINEDNQIEIANLKDKLLKLENQRDKLQRQLSEEKEENDLKFRKSEQN 3210

Query: 1046 YESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMN 1105
            YE+++A   TK + + +E + +S+     KQ   EL     E      ++K  K+    +
Sbjct: 3211 YENQIASLDTKYKRLLDEFKYLSESYEHKKQ---ELNQFKEELPQIANKIKNEKIELTKS 3267

Query: 1106 IPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLN 1165
            I + E  +   +I+      N V             + + + E+       LQ Q   L 
Sbjct: 3268 IEEKEKQLDILSIQ------NKVSNEKILDLESQVNIMINKNEQIQNTYLALQTQYQVLE 3321

Query: 1166 TELQECYTKIIQLETLNTELTGHDVVN----QEQINQLKSKLEQLNTENDNLLSTVAELR 1221
             +  + + KI QLE  N     H  ++    + Q++Q K ++ +L T+N  L+  ++   
Sbjct: 3322 NKYTQQHKKIQQLEKQNDNTKSHLTISLQQAETQLSQTKMQIIELETKNKRLIDDISRAN 3381

Query: 1222 SSISSAVDQR-----GF--EIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDS 1274
                   DQ       F  E+ E+ ++ +      F++ + EL  ++    ++  QL   
Sbjct: 3382 HLKQLMKDQMEDLEINFKKEMDEVREESIKDLNNKFEREKRELNFKIQKLGNQVRQLESD 3441

Query: 1275 VQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQ 1310
                 Q+   K   +E +T    ++ ++E++L   Q
Sbjct: 3442 KDIMKQDLDAKQREVESITLQLQRVAEREKNLYQKQ 3477



 Score =  120 bits (289), Expect = 3e-25
 Identities = 196/1012 (19%), Positives = 440/1012 (43%), Gaps = 77/1012 (7%)

Query: 538  KQMQKTIDNFSKVSDSNKEIVRLTEELH-HLSQKVAELEEEKGNLQLHLVDYD-SGRMIE 595
            KQ+ + ++    + +S  ++  + E +   +   V +  +++ N  LH   +  +G   +
Sbjct: 2508 KQINQQVNKNQILRNSISQLKNIDENIQKQIKSNVEDKMQQEQNSSLHSETFSLNGTFDQ 2567

Query: 596  SDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQV 655
            +    K   ++N+  T  K  S  +S +  +++      Q    +  K  +I  L+    
Sbjct: 2568 TREILKERNLQNMINTASKNFSKAQSHEQKIIELQTDRSQLLKMIATKQLEIDDLKQKNN 2627

Query: 656  CSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQ 715
               I    L ++ID L    ++L    + L  D +QL   +    N     M +     +
Sbjct: 2628 QEAI----LIQRIDKLVEENEQLNFQNQKLAQDYQQLNERV----NQNLKYMKEYNLLNE 2679

Query: 716  ENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYK 775
            EN  L +K E+   E + +L  KI         T   +  + QE+   ++  E E S+ +
Sbjct: 2680 ENQSLCEKTEEYQ-ELLDKLEIKITILSNEN-NTLLKMMEEKQEQIELLKQREEEHSQSQ 2737

Query: 776  SRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDR 835
            + + + ++   ++E +   +++   QL    ++ +   +E   Q+++           + 
Sbjct: 2738 NSMTKFQD---LLEKKNQLIKQLEKQLREAQEQNKVLNNEIIFQQEQFTEDKLNEAVSNI 2794

Query: 836  VVEKQLL--EIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESES 893
            V EK  L  +I  EN   + K + LLEEN++LQ  ++      NA+   A++    + E+
Sbjct: 2795 VSEKNTLIEQISAENSNFKIKIKSLLEENKSLQEKVAKQ----NAIEWYADQLKTTK-ET 2849

Query: 894  TKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEK--YE 951
             +    ++D      R   E++ LI Q+ K+I DL  E   Q+E  +++ K+L  K  Y+
Sbjct: 2850 IEENQMIKD------RQLIENKELI-QEMKKIIDLNKE---QLE--LKENKILQLKQTYD 2897

Query: 952  KNIEYVT-QLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINE 1010
            K  E +  + E Q+ E    I+   + +E+     L L  K + +++ ++  + +Q+  +
Sbjct: 2898 KEKEAILRETEHQINEKLEEIKAYTLEIEKFRD-ELVLTKKQLMEEKNRADYFQDQF--K 2954

Query: 1011 INKLNALLKQKDEEIIALNQKINNAQ-----VSYMSMVSDYESKLAQFTTKLENMEEEMQ 1065
            I   N   ++  +E I +N  + N +     + +++ + D ++K    T KL+ M     
Sbjct: 2955 IYMGNQEHQKFQQEQIIMNTCLENKRSQQDKIHFLNEIEDLKNKNIAVTDKLDQMIAVND 3014

Query: 1066 RVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEM---NIPKTEGM---IISST-- 1117
             +++ L   K+ ++E+Q L+ E+D  + E ++ ++  E    N+ + E      +  T  
Sbjct: 3015 NLTEVL---KEKSQEIQELLIEKDKLLYEREQEQIQLERIQNNLHQLEEERENFLKETQD 3071

Query: 1118 IEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQ 1177
            +  + +  ++ +            L++Q++E    E+   Q+   +L    QE      Q
Sbjct: 3072 VYELKEKVSHQETNRYKQQIEDLKLQIQQKEFETNEQ--FQKNLNQLEQSQQEIIQLKDQ 3129

Query: 1178 LETLN---TELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFE 1234
            +  LN   +++   D +  ++     S L +L   N++    +A L+  +    +QR  +
Sbjct: 3130 INKLNYQISQIQSEDRLKIQERVHFDSTLLELQKINEDNQIEIANLKDKLLKLENQRD-K 3188

Query: 1235 IAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTM----E 1290
            +     +   + +  F+K+E     Q+++ ++KY++LLD  +  ++   +K   +    E
Sbjct: 3189 LQRQLSEEKEENDLKFRKSEQNYENQIASLDTKYKRLLDEFKYLSESYEHKKQELNQFKE 3248

Query: 1291 QVTSLQNKLQ-DKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXX 1349
            ++  + NK++ +K E  ++++EK   +   I  +++++ +EK+                 
Sbjct: 3249 ELPQIANKIKNEKIELTKSIEEKEKQL--DILSIQNKVSNEKILDLESQVNIMINKNEQI 3306

Query: 1350 XD----LRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLEL 1405
             +    L+T+ Q  +    Q    I +   Q   +             +++  + +++EL
Sbjct: 3307 QNTYLALQTQYQVLENKYTQQHKKIQQLEKQNDNTKSHLTISLQQAETQLSQTKMQIIEL 3366

Query: 1406 THQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEY-EKRIEDLTYEKESELAILRL 1464
              + +    +I +  H   +   Q  D   N ++++ E  E+ I+DL  + E E   L  
Sbjct: 3367 ETKNKRLIDDISRANHLKQLMKDQMEDLEINFKKEMDEVREESIKDLNNKFEREKRELNF 3426

Query: 1465 KMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQ-VAELNKALEEE 1515
            K+ +  N    ++ + +I +  L  +   +  ES++L  Q VAE  K L ++
Sbjct: 3427 KIQKLGNQVRQLESDKDIMKQDL--DAKQREVESITLQLQRVAEREKNLYQK 3476



 Score =  109 bits (261), Expect = 8e-22
 Identities = 181/908 (19%), Positives = 401/908 (44%), Gaps = 64/908 (7%)

Query: 231  EWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXX 290
            E + ++ +LLK I +K + I  L++ N   EA   +      KL +E EQ          
Sbjct: 2600 ELQTDRSQLLKMIATKQLEIDDLKQKNNQ-EAILIQ---RIDKLVEENEQLNFQNQKLAQ 2655

Query: 291  XXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKI-ELLEHLNCQIRQTNKELENKL 349
                L  + +  + +   E       E  ++ E T++  ELL+ L  +I   + E    L
Sbjct: 2656 DYQQL-NERVNQNLKYMKEYNLLNE-ENQSLCEKTEEYQELLDKLEIKITILSNENNTLL 2713

Query: 350  ATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAK 409
              M  + + +         L+ ++   ++ S+      Q   E  NQ   K++ K ++ +
Sbjct: 2714 KMMEEKQEQIE--------LLKQREEEHSQSQNSMTKFQDLLEKKNQ-LIKQLEK-QLRE 2763

Query: 410  LEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQH-MEGPSLIHV 468
             +   + LN +++ ++   +E D            K+TLI Q+  E+    ++  SL+  
Sbjct: 2764 AQEQNKVLNNEIIFQQEQFTE-DKLNEAVSNIVSEKNTLIEQISAENSNFKIKIKSLLEE 2822

Query: 469  GTNTEDV----NEIAKVQEQLK--QELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAA 522
              + ++     N I    +QLK  +E  +E + +  + LIE     +E I ++   ID  
Sbjct: 2823 NKSLQEKVAKQNAIEWYADQLKTTKETIEENQMIKDRQLIEN----KELIQEMKKIIDL- 2877

Query: 523  NKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQ 582
            NK  +++K N  L+LKQ     +  + + ++  +I    EE+   + ++ +  +E    +
Sbjct: 2878 NKEQLELKENKILQLKQTYDK-EKEAILRETEHQINEKLEEIKAYTLEIEKFRDELVLTK 2936

Query: 583  LHLVDYDSGRMIESDVYKKMI---EMENLAETRLKAISLLESQKFDLVQELHILQQKYDE 639
              L++  +      D +K  +   E +   + ++   + LE+++     ++H L +  D 
Sbjct: 2937 KQLMEEKNRADYFQDQFKIYMGNQEHQKFQQEQIIMNTCLENKRSQQ-DKIHFLNEIEDL 2995

Query: 640  VEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDL 699
                +A   +L  DQ+ +   + +L E +   S   +EL +  + L  ++EQ    ++ +
Sbjct: 2996 KNKNIAVTDKL--DQMIAV--NDNLTEVLKEKSQEIQELLIEKDKLLYEREQEQIQLERI 3051

Query: 700  ENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQE 759
            +N+   +  + +N+++E  D+ +  EK+S ++ +    +I   +    Q +F  + + Q+
Sbjct: 3052 QNNLHQLEEERENFLKETQDVYELKEKVSHQETNRYKQQIEDLKLQIQQKEFETNEQFQK 3111

Query: 760  RDLYIENIESELSKYKSRICRLEESIA-VMEDRRYSLERKADQLGSYLQEKQKAYSEYTI 818
                +E  + E+ + K +I +L   I+ +  + R  ++ +     S L E QK   +  I
Sbjct: 3112 NLNQLEQSQQEIIQLKDQINKLNYQISQIQSEDRLKIQERV-HFDSTLLELQKINEDNQI 3170

Query: 819  QEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNA 878
            +   L ++L  L +    +++QL E + EN    +K++      QN +  ++ +   Y  
Sbjct: 3171 EIANLKDKLLKLENQRDKLQRQLSEEKEENDLKFRKSE------QNYENQIASLDTKYKR 3224

Query: 879  LVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFN-TQIE 937
            L+++     L+ES   K Q +L   +  L +I ++ +   ++  K IE+ E + +   I+
Sbjct: 3225 LLDEFKY--LSESYEHKKQ-ELNQFKEELPQIANKIKNEKIELTKSIEEKEKQLDILSIQ 3281

Query: 938  SAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQ 997
            + + ++K+L+   E  +  +     Q+Q     ++     +E  NK   +   K +Q+ +
Sbjct: 3282 NKVSNEKILD--LESQVNIMINKNEQIQNTYLALQTQYQVLE--NKYTQQ--HKKIQQLE 3335

Query: 998  TQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKL 1057
             Q+ +        + +    L Q   +II L  K N   +  +S  +  +  +      L
Sbjct: 3336 KQNDNTKSHLTISLQQAETQLSQTKMQIIELETK-NKRLIDDISRANHLKQLMKDQMEDL 3394

Query: 1058 E-NMEEEMQRVSKQL---LDSKQHNE--ELQILVREQDDQIKELKETKLTFEMNIPKTEG 1111
            E N ++EM  V ++    L++K   E  EL   +++  +Q+++L+  K   + ++   + 
Sbjct: 3395 EINFKKEMDEVREESIKDLNNKFEREKRELNFKIQKLGNQVRQLESDKDIMKQDLDAKQR 3454

Query: 1112 MIISSTIE 1119
             + S T++
Sbjct: 3455 EVESITLQ 3462



 Score = 86.2 bits (204), Expect = 7e-15
 Identities = 175/892 (19%), Positives = 387/892 (43%), Gaps = 85/892 (9%)

Query: 696  IKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKI------NHEEQSKIQT 749
            I++L+++ + I N   N +  N +   ++E+ + +K ++L +K       N+   S+   
Sbjct: 2375 IQNLQSNPQVINNGTNNIVYINQETQKRIEEQN-KKFNKLFSKDKGQHNPNNFSFSQKNQ 2433

Query: 750  QFGIDAKIQERDLYIE-NIESELSKYKSRICRLEES---IAVMEDR---RYSLER----- 797
            Q   +++IQ+++ + + N +++     SR  R   S   IA        +Y + R     
Sbjct: 2434 QSIQNSQIQQQNQFQQSNQQNQNQLESSRTLRSASSNPNIAANTQPIQLQYVISRNQLNQ 2493

Query: 798  -KADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQ 856
             +  Q  + + +  K  ++   +   L N ++ L + D  ++KQ+ +   E+K  Q++N 
Sbjct: 2494 PQQQQQANIIPDNSKQINQQVNKNQILRNSISQLKNIDENIQKQI-KSNVEDKMQQEQNS 2552

Query: 857  ILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQT 916
             L  E  +L  +    ++    ++++ N  ++  + S  +       +  ++  T   Q 
Sbjct: 2553 SLHSETFSLNGTFDQTRE----ILKERNLQNMINTASKNFSKAQSHEQKIIELQTDRSQL 2608

Query: 917  L--IVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENL 974
            L  I  K+ EI+DL+ + N +     R  K++ E  + N     Q +   Q+Y+   E +
Sbjct: 2609 LKMIATKQLEIDDLKQKNNQEAILIQRIDKLVEENEQLNF----QNQKLAQDYQQLNERV 2664

Query: 975  NMNVEE------LNKMNLELIDKHVQKQQTQSPDYTEQYI--NEINKLNALLKQKDEEII 1026
            N N++       LN+ N  L +K  + Q+       +  I  NE N L  ++++K E+I 
Sbjct: 2665 NQNLKYMKEYNLLNEENQSLCEKTEEYQELLDKLEIKITILSNENNTLLKMMEEKQEQIE 2724

Query: 1027 ALNQKINNAQVSYMSMVS--DYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQIL 1084
             L Q+      S  SM    D   K  Q   +LE    E Q  +K L +     +E Q  
Sbjct: 2725 LLKQREEEHSQSQNSMTKFQDLLEKKNQLIKQLEKQLREAQEQNKVLNNEIIFQQE-QFT 2783

Query: 1085 VREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXL-K 1143
              + ++ +  +   K T    I   E       I+ + ++  ++               +
Sbjct: 2784 EDKLNEAVSNIVSEKNTLIEQI-SAENSNFKIKIKSLLEENKSLQEKVAKQNAIEWYADQ 2842

Query: 1144 VQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKL 1203
            ++  +E I+E  +++++    N EL +   KII L     EL  + ++  +Q    K K 
Sbjct: 2843 LKTTKETIEENQMIKDRQLIENKELIQEMKKIIDLNKEQLELKENKILQLKQTYD-KEK- 2900

Query: 1204 EQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQRE-ADFQKTEHELRVQLS 1262
            E +  E ++ ++   E   + +  +++   E+    KQ + ++  AD+ + + ++ +   
Sbjct: 2901 EAILRETEHQINEKLEEIKAYTLEIEKFRDELVLTKKQLMEEKNRADYFQDQFKIYMGNQ 2960

Query: 1263 AFESKYEQ---LLDSVQSSTQEETNKIVTMEQVTSLQNK---LQDKEEHLRNLQEKYADV 1316
              + K++Q   ++++   + + + +KI  + ++  L+NK   + DK + +  + +   +V
Sbjct: 2961 EHQ-KFQQEQIIMNTCLENKRSQQDKIHFLNEIEDLKNKNIAVTDKLDQMIAVNDNLTEV 3019

Query: 1317 INQI--EILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEEN 1374
            + +   EI    IE +K+ +                  R + Q   +  + ++  + EE 
Sbjct: 3020 LKEKSQEIQELLIEKDKLLYE-----------------REQEQIQLERIQNNLHQLEEER 3062

Query: 1375 AQ-LKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRN-D 1432
               LK++               N  + ++ +L  Q++ K+ E    T+E      Q+N +
Sbjct: 3063 ENFLKETQDVYELKEKVSHQETNRYKQQIEDLKLQIQQKEFE----TNEQF----QKNLN 3114

Query: 1433 EFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELN 1492
            + E  +Q++++ + +I  L Y+     +  RLK+ E  +   T+ +  +I     IE  N
Sbjct: 3115 QLEQSQQEIIQLKDQINKLNYQISQIQSEDRLKIQERVHFDSTLLELQKINEDNQIEIAN 3174

Query: 1493 VKITESVSLNKQVAELNKALEEEVAKTN-EMQTALENQEIEIVTLNDEITNL 1543
            +K  + + L  Q  +L + L EE  + + + + + +N E +I +L+ +   L
Sbjct: 3175 LK-DKLLKLENQRDKLQRQLSEEKEENDLKFRKSEQNYENQIASLDTKYKRL 3225



 Score = 79.4 bits (187), Expect = 8e-13
 Identities = 187/859 (21%), Positives = 369/859 (42%), Gaps = 124/859 (14%)

Query: 235  EKQRLLKDIESKDVRISS----LEEANKLLEAARF--EISLEHSKLAQELEQXXXXXXXX 288
            + Q+L +D +  + R++     ++E N L E  +   E + E+ +L  +LE         
Sbjct: 2649 QNQKLAQDYQQLNERVNQNLKYMKEYNLLNEENQSLCEKTEEYQELLDKLEIKITILSNE 2708

Query: 289  XXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTE----LTKKIELLEHLNCQIRQT--- 341
                  + ++  E   E   + EE+ S    +MT+    L KK +L++ L  Q+R+    
Sbjct: 2709 NNTLLKMMEEKQE-QIELLKQREEEHSQSQNSMTKFQDLLEKKNQLIKQLEKQLREAQEQ 2767

Query: 342  NKELENKLATMG---TESK---AVSSPSKKGSPLISRKSGRNTASKMK-----SPWSQLS 390
            NK L N++       TE K   AVS+   + + LI + S  N+  K+K          L 
Sbjct: 2768 NKVLNNEIIFQQEQFTEDKLNEAVSNIVSEKNTLIEQISAENSNFKIKIKSLLEENKSLQ 2827

Query: 391  SETLNQD-----------TDKKINKNEIAKLEMVIQSLNKDLVD--KEYVISEKDTXXXX 437
             +   Q+           T + I +N++ K   +I+  NK+L+   K+ +   K+     
Sbjct: 2828 EKVAKQNAIEWYADQLKTTKETIEENQMIKDRQLIE--NKELIQEMKKIIDLNKEQLELK 2885

Query: 438  XXXXXXGKDTLIAQLQ--LEHQQHMEGPSLIHVGTNTEDV----NEIAKVQEQLKQELN- 490
                   K T   + +  L   +H     L  +   T ++    +E+   ++QL +E N 
Sbjct: 2886 ENKILQLKQTYDKEKEAILRETEHQINEKLEEIKAYTLEIEKFRDELVLTKKQLMEEKNR 2945

Query: 491  -----DEIK--------------DVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKS 531
                 D+ K               + +   +E  +S +++I  LN+  D  NKN+     
Sbjct: 2946 ADYFQDQFKIYMGNQEHQKFQQEQIIMNTCLENKRSQQDKIHFLNEIEDLKNKNIAVTD- 3004

Query: 532  NHKLKLKQMQKTIDNFSKV-SDSNKEIVRLTEE----LHHLSQKVAELEEEKGNLQLHLV 586
                KL QM    DN ++V  + ++EI  L  E    L+   Q+  +LE  + NL     
Sbjct: 3005 ----KLDQMIAVNDNLTEVLKEKSQEIQELLIEKDKLLYEREQEQIQLERIQNNLHQLEE 3060

Query: 587  DYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLAD 646
            + ++      DVY+   ++ +    R K       Q  DL  +L I Q++++  E    +
Sbjct: 3061 ERENFLKETQDVYELKEKVSHQETNRYK------QQIEDL--KLQIQQKEFETNEQFQKN 3112

Query: 647  ISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLY-GTIKDLENDKED 705
            ++QL+  Q   EI  + L++QI+ L+    ++    + LK+ +   +  T+ +L+   ED
Sbjct: 3113 LNQLEQSQ--QEI--IQLKDQINKLNYQISQIQSE-DRLKIQERVHFDSTLLELQKINED 3167

Query: 706  IMNKLQNYIQENMDLT---DKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQ---E 759
               ++ N   + + L    DKL++  +E+  E   K    EQ+       +D K +   +
Sbjct: 3168 NQIEIANLKDKLLKLENQRDKLQRQLSEEKEENDLKFRKSEQNYENQIASLDTKYKRLLD 3227

Query: 760  RDLYI----ENIESELSKYKSRICRLEESIAVME-DRRYSLERKADQLGSYLQEKQKAYS 814
               Y+    E+ + EL+++K  + ++   I   + +   S+E K  QL   L  + K  +
Sbjct: 3228 EFKYLSESYEHKKQELNQFKEELPQIANKIKNEKIELTKSIEEKEKQL-DILSIQNKVSN 3286

Query: 815  EYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQ 874
            E  +  +  VN   ++++ +  ++   L ++ + + L+ K     ++ Q L+    + + 
Sbjct: 3287 EKILDLESQVN---IMINKNEQIQNTYLALQTQYQVLENKYTQQHKKIQQLEKQNDNTKS 3343

Query: 875  HYNALVEKANRTDLAESEST--KYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEF 932
            H    +++A  T L++++    + +T+ + L  ++ R  H  Q +    K ++EDLEI F
Sbjct: 3344 HLTISLQQAE-TQLSQTKMQIIELETKNKRLIDDISRANHLKQLM----KDQMEDLEINF 3398

Query: 933  NTQI----ESAIRD--------KKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEE 980
              ++    E +I+D        K+ LN K +K    V QLE+     K +++     VE 
Sbjct: 3399 KKEMDEVREESIKDLNNKFEREKRELNFKIQKLGNQVRQLESDKDIMKQDLDAKQREVES 3458

Query: 981  LNKMNLELIDKHVQKQQTQ 999
            +      + ++     Q Q
Sbjct: 3459 ITLQLQRVAEREKNLYQKQ 3477



 Score = 69.7 bits (163), Expect = 6e-10
 Identities = 145/730 (19%), Positives = 297/730 (40%), Gaps = 56/730 (7%)

Query: 849  KELQKKNQILLEENQNLQISLSDMQQHY--NALVEKANRTDLAESESTKYQTQLRDLESN 906
            +++Q K Q  L  N+NL   +  +Q H   N    +A      ++  +  Q  + +  +N
Sbjct: 2334 QQVQAKLQPNLANNKNLPYQMV-IQPHIQQNQFSNQAQNIQPIQNLQSNPQV-INNGTNN 2391

Query: 907  LKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQE 966
            +  I  E Q  I ++ K+   L   F+        +    ++K +++I+  +Q++ Q Q 
Sbjct: 2392 IVYINQETQKRIEEQNKKFNKL---FSKDKGQHNPNNFSFSQKNQQSIQN-SQIQQQNQF 2447

Query: 967  YKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEII 1026
             ++N +N N  +E    +     + ++    TQ      QY+   N+LN   +Q+   II
Sbjct: 2448 QQSNQQNQNQ-LESSRTLRSASSNPNIAAN-TQPIQL--QYVISRNQLNQPQQQQQANII 2503

Query: 1027 ALNQKINNAQVSYMSMVSDYESKLAQFTTKLE-NMEEEMQRVSKQLLDSKQHNEELQILV 1085
              N K  N QV+   ++ +  S+L      ++  ++  ++   +Q  +S  H+E   +  
Sbjct: 2504 PDNSKQINQQVNKNQILRNSISQLKNIDENIQKQIKSNVEDKMQQEQNSSLHSETFSL-- 2561

Query: 1086 REQDDQIKE-LKETKLTFEMNIPK---TEGMIISSTIEPMSDDANNVDXXXXXXXXXXXX 1141
                DQ +E LKE  L   +N      ++       I  +  D + +             
Sbjct: 2562 NGTFDQTREILKERNLQNMINTASKNFSKAQSHEQKIIELQTDRSQLLKMIATKQLEIDD 2621

Query: 1142 LKVQEEEE--FIQERSVLQEQSAKLNTELQECYTKIIQL-ETLNTELTGHDVVNQEQINQ 1198
            LK +  +E   IQ    L E++ +LN + Q+      QL E +N  L      N   +N+
Sbjct: 2622 LKQKNNQEAILIQRIDKLVEENEQLNFQNQKLAQDYQQLNERVNQNLKYMKEYN--LLNE 2679

Query: 1199 LKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQH---LAQREADFQKTEH 1255
                L +   E   LL  + E++ +I S  +    ++ E  ++    L QRE +  ++++
Sbjct: 2680 ENQSLCEKTEEYQELLDKL-EIKITILSNENNTLLKMMEEKQEQIELLKQREEEHSQSQN 2738

Query: 1256 ELRVQLSAFESKYEQLLDSVQSSTQE--ETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKY 1313
             +       E K  QL+  ++   +E  E NK++  E +   +   +DK      L E  
Sbjct: 2739 SMTKFQDLLEKK-NQLIKQLEKQLREAQEQNKVLNNEIIFQQEQFTEDK------LNEAV 2791

Query: 1314 ADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQ-SYKQMQEQSILNINE 1372
            ++++++   L  +I  E   F                 +  +N   +   Q ++     E
Sbjct: 2792 SNIVSEKNTLIEQISAENSNFKIKIKSLLEENKSLQEKVAKQNAIEWYADQLKTTKETIE 2851

Query: 1373 ENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLT--QR 1430
            EN  +K               ++ D   + LEL     L+  + Y K  E  +  T  Q 
Sbjct: 2852 ENQMIKDRQLIENKELIQEMKKIIDLNKEQLELKENKILQLKQTYDKEKEAILRETEHQI 2911

Query: 1431 NDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEE 1490
            N++ E ++   +E EK           EL + + ++ E  N  +  Q +    ++ +  +
Sbjct: 2912 NEKLEEIKAYTLEIEK--------FRDELVLTKKQLMEEKNRADYFQDQF---KIYMGNQ 2960

Query: 1491 LNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEI----TNLQNM 1546
             + K  +   +     E  ++ ++++   NE++  L+N+ I +    D++     NL  +
Sbjct: 2961 EHQKFQQEQIIMNTCLENKRSQQDKIHFLNEIED-LKNKNIAVTDKLDQMIAVNDNLTEV 3019

Query: 1547 VRASSSKIQK 1556
            ++  S +IQ+
Sbjct: 3020 LKEKSQEIQE 3029



 Score = 61.7 bits (143), Expect = 2e-07
 Identities = 144/740 (19%), Positives = 309/740 (41%), Gaps = 68/740 (9%)

Query: 151  IKEKDNALSVLQVKMKIMETTILDLQE-----KINEK-DQIIEAKNKATTXXXXXXXXXX 204
            IK+ +  L   Q + K++   I+  QE     K+NE    I+  KN              
Sbjct: 2754 IKQLEKQLREAQEQNKVLNNEIIFQQEQFTEDKLNEAVSNIVSEKNTLIEQISAENSNFK 2813

Query: 205  XXXXXXXEDTKQQMTKM-QENFIAMEAEWKDEKQRLLKDI--ESKDVRISSLEEANKLLE 261
                   E+ K    K+ ++N I    EW  ++ +  K+   E++ ++   L E  +L++
Sbjct: 2814 IKIKSLLEENKSLQEKVAKQNAI----EWYADQLKTTKETIEENQMIKDRQLIENKELIQ 2869

Query: 262  AARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANM 321
              +  I L   +L  +  +              + +++ E    EK E  +  +LEI   
Sbjct: 2870 EMKKIIDLNKEQLELKENKILQLKQTYDKEKEAILRET-EHQINEKLEEIKAYTLEIEKF 2928

Query: 322  TE---LTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNT 378
             +   LTKK +L+E  N   R    + + K+     E +         +  +  K  +  
Sbjct: 2929 RDELVLTKK-QLMEEKN---RADYFQDQFKIYMGNQEHQKFQQEQIIMNTCLENKRSQQD 2984

Query: 379  ASKMKSPWSQLSSETLNQDTDK-----KINKNEIAKLEMVIQSLNKDLVDKEYVISEKDT 433
                 +    L ++ +   TDK      +N N    L+   Q + + L++K+ ++ E++ 
Sbjct: 2985 KIHFLNEIEDLKNKNIAV-TDKLDQMIAVNDNLTEVLKEKSQEIQELLIEKDKLLYEREQ 3043

Query: 434  XXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHV---GTNTEDVNEIAKVQEQLKQELN 490
                           + QL+ E +  ++    ++      + ++ N   +  E LK ++ 
Sbjct: 3044 EQIQLERIQNN----LHQLEEERENFLKETQDVYELKEKVSHQETNRYKQQIEDLKLQIQ 3099

Query: 491  DEIKDVN--VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQ---MQKTID 545
             +  + N   +  + +L+ ++++I QL D+I+  N  + +++S  +LK+++      T+ 
Sbjct: 3100 QKEFETNEQFQKNLNQLEQSQQEIIQLKDQINKLNYQISQIQSEDRLKIQERVHFDSTLL 3159

Query: 546  NFSKVSDSNK-EIVRLTEELHHLSQKVAEL------EEEKGNLQLHLVDYDSGRMIES-- 596
               K+++ N+ EI  L ++L  L  +  +L      E+E+ +L+    + +    I S  
Sbjct: 3160 ELQKINEDNQIEIANLKDKLLKLENQRDKLQRQLSEEKEENDLKFRKSEQNYENQIASLD 3219

Query: 597  DVYKKMI-EMENLAETRLKAISLLESQKFDLVQELHILQQKYDE----VEDKLADISQLQ 651
              YK+++ E + L+E+       L   K +L Q  + ++ +  E    +E+K   +  L 
Sbjct: 3220 TKYKRLLDEFKYLSESYEHKKQELNQFKEELPQIANKIKNEKIELTKSIEEKEKQLDILS 3279

Query: 652  SDQVCSEIKSVHLEEQIDALSASKKE-----LALVIENLKLDKE--QLYGTIKDLENDKE 704
                 S  K + LE Q++ +    ++     LAL  +   L+ +  Q +  I+ LE   +
Sbjct: 3280 IQNKVSNEKILDLESQVNIMINKNEQIQNTYLALQTQYQVLENKYTQQHKKIQQLEKQND 3339

Query: 705  DIMNKLQNYIQE-NMDLTD-KLEKMSAE----KISELLAKINHEEQ-SKIQTQ-FGIDAK 756
            +  + L   +Q+    L+  K++ +  E    ++ + +++ NH +Q  K Q +   I+ K
Sbjct: 3340 NTKSHLTISLQQAETQLSQTKMQIIELETKNKRLIDDISRANHLKQLMKDQMEDLEINFK 3399

Query: 757  IQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEY 816
             +  ++  E+I+   +K++     L   I  + ++   LE   D +   L  KQ+     
Sbjct: 3400 KEMDEVREESIKDLNNKFEREKRELNFKIQKLGNQVRQLESDKDIMKQDLDAKQREVESI 3459

Query: 817  TIQEDELVNRLAVLMDHDRV 836
            T+Q   +  R   L    R+
Sbjct: 3460 TLQLQRVAEREKNLYQKQRL 3479


>UniRef50_UPI00006CCC54 Cluster: hypothetical protein TTHERM_00335640;
            n=1; Tetrahymena thermophila SB210|Rep: hypothetical
            protein TTHERM_00335640 - Tetrahymena thermophila SB210
          Length = 1512

 Score =  128 bits (309), Expect = 1e-27
 Identities = 201/1019 (19%), Positives = 451/1019 (44%), Gaps = 85/1019 (8%)

Query: 308  TEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELEN---KLATMGTESKAVSSPSK 364
            T+I +   ++I N+ +   K+      N +++ +N +L+    +L+ + TE++A+     
Sbjct: 344  TQINDVQQVKIKNLEQALDKVN---EENIKLQSSNLDLDQVKTELSVIKTENEALRQSQT 400

Query: 365  KGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDK 424
             GS  ++++        ++           + +   K+N + I++LE  I  + K+L +K
Sbjct: 401  SGSESLTQEIKLLEQQYLQEKDKNHHLVAAHSEEILKLN-HHISELEDQIVHIQKELNEK 459

Query: 425  EYVISEKDTXXXXXXXXXXGKDTLIAQL-QLEHQQHMEGPSLIHVGT-NTEDVNEIAKVQ 482
               + +              K+T+   L + E     E   ++H+ + N  +V+ + +  
Sbjct: 460  SIQVQQLQKEKEIILVE---KNTISQSLVEKETIIEKEKKEIVHISSVNESEVHSLREQI 516

Query: 483  EQLKQE--LNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQM 540
             +L+ E  LN E +  +   LIE LK     I + + ++    + +++V+   ++K+ + 
Sbjct: 517  SKLQSEIRLNSEGQQNDFTALIEALK---RDIEEKDQQLKQLREFVMEVQHAGQIKVLER 573

Query: 541  QKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYK 600
            ++ +    K+ +S KE      EL  LS K+ ++  EK       V  + G + ES    
Sbjct: 574  EQQLLEKDKIIESQKE------ELMLLSSKLEQVIREK----TFTVSGEIGHVTESVRID 623

Query: 601  KMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDE--VEDKLADISQLQSDQVCSE 658
               + +   ET +K            VQE+ I  ++ +E  VE+   D+   Q+ +   E
Sbjct: 624  VKSQNKERQETEVK----------QQVQEIPIEGEEEEEAGVEEVEFDMEVKQAKETRQE 673

Query: 659  IKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLEN---DKEDIMN-KLQNYI 714
                   +Q  +LS    E   V +NL  +K+ L   + +L     D E   N K+  Y 
Sbjct: 674  GDKQGFFDQASSLSKELMENKQVQDNLLKEKDGLSKKVTELNVKYLDAEKQNNEKIAQYQ 733

Query: 715  QENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAK-IQERDLYIENIESELSK 773
            ++  +L  +++K+  + + EL  +I  +++   Q Q   DAK + E +   +  ++++  
Sbjct: 734  KQEAELKQQIQKLQ-QNVDELTKQIQSQKE---QLQQDADAKLVNETNKIKQGHQAKVIY 789

Query: 774  YKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDH 833
              + I  L+E +   E++  S +R +  L S      +  +++ ++  EL N    L  +
Sbjct: 790  LNAEIAALKEKLN--EEKTQSEQRVSQVLQSQNSSSSELITKHELRVTELQNNFN-LQRN 846

Query: 834  DRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLS-DMQQHYNALVEKANRTDLAESE 892
            D  +E ++++++H+   L++K   L +E  N +  ++ ++  + ++L E+A   +L  +E
Sbjct: 847  D--LETKIVDLQHQLAALEQK---LRDEKSNHEALINQNIASNKSSLDEQARGYELKLAE 901

Query: 893  STK-YQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQI---ESAIRDKKVLNE 948
              K Y+ ++ ++ S  ++ + E +   +  KK+I +L+ +    +   E      K L +
Sbjct: 902  QQKSYELKITEINSKHQQASQEVE---INYKKQITELQAQSQLNLKLFEERETTTKQLEQ 958

Query: 949  KYEKNIEYVTQLE-AQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQY 1007
             + + I+ +     +++   KN        +++ NK  +  +   +Q  + Q  +  + +
Sbjct: 959  NHSQAIQNIKDTHLSEINNLKNQFSADQAKLQQENKAVITQLKAQIQNLEIQINELNQNH 1018

Query: 1008 INEINKLNALLKQKDEEI-IALNQKINNAQVSYMSMVSDY-ESKLAQFTTKLENMEEEMQ 1065
              +I  LN   + K  ++ +   Q I+  + S+ + +S   E+   + +   E  ++++ 
Sbjct: 1019 SIQIQNLNKDHQAKLTQVEVQYKQTISTIEESHKTYISSIQENHKKEISLAEEASKKQLN 1078

Query: 1066 RVSKQLLDS--KQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSD 1123
               +Q L++   Q+ + +  L  E   QI++L++       N+ K     I  TI+  + 
Sbjct: 1079 ASEQQKLETIENQYKQRINNLESEHKLQIEQLEKQHTQKVSNLEKDFQSKIDETIKSYNI 1138

Query: 1124 DANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVL----QEQSAKLNTELQECYTKIIQLE 1179
                ++            + + E+EE   + S      Q++ A+L  E+ E   KI   E
Sbjct: 1139 KIQEIEKNYSQKIA----IVISEKEELSAQNSAASKGQQDKEAQLQKEISELKLKI---E 1191

Query: 1180 TLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRG--FEIAE 1237
            TL        +  +E+ N L+  ++Q++  + N +S  + ++SS SS+    G    +  
Sbjct: 1192 TLVNNHQKEIIKQEEKYNLLRQTVQQISQNSQN-VSVTSNIQSSSSSSTVNNGDYLVLQH 1250

Query: 1238 LWKQHLAQREADFQKTEHELRVQ--LSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTS 1294
             + Q +   + + +K + E R+   L     K EQ   ++++  +    K  T E  T+
Sbjct: 1251 DYNQLIEVNKENLKKIQEERRLYGILQDDYIKLEQQFTTLKNEKKNSDKKSKTAESNTA 1309



 Score =  101 bits (241), Expect = 2e-19
 Identities = 179/874 (20%), Positives = 387/874 (44%), Gaps = 87/874 (9%)

Query: 496  VNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLK-QMQKTIDNF-SKVSDS 553
            V VK  ++ L   +E++ Q   E     K++  + +  K +++ + +KT+D+  +  ++S
Sbjct: 266  VEVKAQMKYLSHVKEEMLQKQQEYQ---KDISGLLTGMKREMEAEFEKTLDHVHNSQNES 322

Query: 554  N-------KEIVRLTEELHHLSQKVAELEEEK-GNLQ--LHLVDYDSGRMIESDVYKKMI 603
            N       KE+  LTE+L  +S ++ ++++ K  NL+  L  V+ ++ ++  S++    +
Sbjct: 323  NQKSLVLQKEVETLTEKLF-MSTQINDVQQVKIKNLEQALDKVNEENIKLQSSNLDLDQV 381

Query: 604  EME-NLAETRLKAISLLESQKFD-LVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKS 661
            + E ++ +T  +A+   ++   + L QE+ +L+Q+Y + +DK   +    S+++      
Sbjct: 382  KTELSVIKTENEALRQSQTSGSESLTQEIKLLEQQYLQEKDKNHHLVAAHSEEILKLNHH 441

Query: 662  V-HLEEQIDALSASKKELALVIENLKLDKEQLY---GTIKDLENDKEDIMNKLQNYIQEN 717
            +  LE+QI  +     E ++ ++ L+ +KE +     TI     +KE I+ K +  I   
Sbjct: 442  ISELEDQIVHIQKELNEKSIQVQQLQKEKEIILVEKNTISQSLVEKETIIEKEKKEIVHI 501

Query: 718  MDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSR 777
              + +       E+IS+L ++I    + + Q  F    +  +RD  IE  + +L + +  
Sbjct: 502  SSVNESEVHSLREQISKLQSEIRLNSEGQ-QNDFTALIEALKRD--IEEKDQQLKQLREF 558

Query: 778  ICRLEES--IAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDR 835
            +  ++ +  I V+E  +  LE+  D++    +E+    S   +++        V  +   
Sbjct: 559  VMEVQHAGQIKVLEREQQLLEK--DKIIESQKEELMLLSS-KLEQVIREKTFTVSGEIGH 615

Query: 836  VVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKAN-RTDLAESEST 894
            V E   ++++ +NKE Q+      E  Q +Q    + ++   A VE+     ++ +++ T
Sbjct: 616  VTESVRIDVKSQNKERQET-----EVKQQVQEIPIEGEEEEEAGVEEVEFDMEVKQAKET 670

Query: 895  KYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEK-N 953
            + +   +        ++ E     + + K+++D  ++    +   + +  V     EK N
Sbjct: 671  RQEGDKQGFFDQASSLSKE-----LMENKQVQDNLLKEKDGLSKKVTELNVKYLDAEKQN 725

Query: 954  IEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINK 1013
             E + Q + Q  E K  I+ L  NV+EL K          QK+Q Q  D   + +NE NK
Sbjct: 726  NEKIAQYQKQEAELKQQIQKLQQNVDELTKQIQS------QKEQLQQ-DADAKLVNETNK 778

Query: 1014 LNALLKQK----DEEIIALNQKINNAQVSYMSMVSDY----ESKLAQFTTKLENMEEEMQ 1065
            +    + K    + EI AL +K+N  +      VS       S  ++  TK E    E+Q
Sbjct: 779  IKQGHQAKVIYLNAEIAALKEKLNEEKTQSEQRVSQVLQSQNSSSSELITKHELRVTELQ 838

Query: 1066 R-VSKQLLDSKQHNEELQILVREQDDQIKELKET-KLTFEMNIPKTEGMIISSTIE---P 1120
               + Q  D +    +LQ  +   + ++++ K   +     NI   +  +          
Sbjct: 839  NNFNLQRNDLETKIVDLQHQLAALEQKLRDEKSNHEALINQNIASNKSSLDEQARGYELK 898

Query: 1121 MSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTEL-QECYTKIIQLE 1179
            +++   + +               + E  + ++ + LQ QS +LN +L +E  T   QLE
Sbjct: 899  LAEQQKSYELKITEINSKHQQASQEVEINYKKQITELQAQS-QLNLKLFEERETTTKQLE 957

Query: 1180 TLNTE-LTGHDVVNQEQINQLKSKL--EQLNTENDN------LLSTVAELRSSISSAVDQ 1230
              +++ +      +  +IN LK++   +Q   + +N      L + +  L   I+     
Sbjct: 958  QNHSQAIQNIKDTHLSEINNLKNQFSADQAKLQQENKAVITQLKAQIQNLEIQINELNQN 1017

Query: 1231 RGFEIAELWKQH---LAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIV 1287
               +I  L K H   L Q E  +++T       +S  E  ++  + S+Q + ++E    +
Sbjct: 1018 HSIQIQNLNKDHQAKLTQVEVQYKQT-------ISTIEESHKTYISSIQENHKKE----I 1066

Query: 1288 TMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIE 1321
            ++ +  S +     +++ L  ++ +Y   IN +E
Sbjct: 1067 SLAEEASKKQLNASEQQKLETIENQYKQRINNLE 1100



 Score = 85.0 bits (201), Expect = 2e-14
 Identities = 151/763 (19%), Positives = 313/763 (41%), Gaps = 61/763 (7%)

Query: 213  DTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHS 272
            D ++Q  +    +   EAE K + Q+L ++++    +I S +E  +L + A  ++  E +
Sbjct: 720  DAEKQNNEKIAQYQKQEAELKQQIQKLQQNVDELTKQIQSQKE--QLQQDADAKLVNETN 777

Query: 273  KLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEI----ANMTELTKKI 328
            K    ++Q                K+ +    EEKT+ E++ S  +    ++ +EL  K 
Sbjct: 778  K----IKQGHQAKVIYLNAEIAALKEKLN---EEKTQSEQRVSQVLQSQNSSSSELITKH 830

Query: 329  EL-LEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWS 387
            EL +  L         +LE K+  +  +  A+    +           +N AS   S   
Sbjct: 831  ELRVTELQNNFNLQRNDLETKIVDLQHQLAALEQKLRDEKSNHEALINQNIASNKSSLDE 890

Query: 388  QLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDL-VDKEYVISEKDTXXXXXXXXXXGKD 446
            Q     L     +K  + +I ++    Q  ++++ ++ +  I+E              ++
Sbjct: 891  QARGYELKLAEQQKSYELKITEINSKHQQASQEVEINYKKQITELQAQSQLNLKLFEERE 950

Query: 447  TLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLK 506
            T   QL+  H Q ++     H+       N+ +  Q +L+QE N  +    +  L  +++
Sbjct: 951  TTTKQLEQNHSQAIQNIKDTHLSEINNLKNQFSADQAKLQQE-NKAV----ITQLKAQIQ 1005

Query: 507  SAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQ-KTIDNFSKVSDSNKEIVRLTEELH 565
            + E QI +LN       +N+ K   +H+ KL Q++ +     S + +S+K  +   +E H
Sbjct: 1006 NLEIQINELNQNHSIQIQNLNK---DHQAKLTQVEVQYKQTISTIEESHKTYISSIQENH 1062

Query: 566  HLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFD 625
               +K   L EE    QL+  +      IE+  YK+ I   NL       I  LE Q   
Sbjct: 1063 ---KKEISLAEEASKKQLNASEQQKLETIENQ-YKQRI--NNLESEHKLQIEQLEKQHTQ 1116

Query: 626  LVQELH-ILQQKYDEV----EDKLADISQLQSDQVCSEI-KSVHLEEQIDALSASKK--- 676
             V  L    Q K DE       K+ +I +  S ++   I +   L  Q  A S  ++   
Sbjct: 1117 KVSNLEKDFQSKIDETIKSYNIKIQEIEKNYSQKIAIVISEKEELSAQNSAASKGQQDKE 1176

Query: 677  -ELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISEL 735
             +L   I  LKL  E L    +     +E+  N L+  +Q+    +  +   S  + S  
Sbjct: 1177 AQLQKEISELKLKIETLVNNHQKEIIKQEEKYNLLRQTVQQISQNSQNVSVTSNIQSSSS 1236

Query: 736  LAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKY---KSRICRLEESIAVMEDRR 792
             + +N+ +   +Q  +    ++ + +L  + I+ E   Y   +    +LE+    +++ +
Sbjct: 1237 SSTVNNGDYLVLQHDYNQLIEVNKENL--KKIQEERRLYGILQDDYIKLEQQFTTLKNEK 1294

Query: 793  YSLERK---------ADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLE 843
             + ++K         A       Q K KAY E   +  + +    + +  +  + +  L+
Sbjct: 1295 KNSDKKSKTAESNTAATTTSGASQLKNKAYFEVDQRVSKELELTVLKLKEENAIIRDQLK 1354

Query: 844  IEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTK----YQTQ 899
             E+E+K    + Q +  E +   I L  ++    A+ ++    D  ++           +
Sbjct: 1355 KEYEDKIYSLEKQAI--EYEKKMIELEQVKVELKAMKDEKEEADWEKARKNNGNKGASKE 1412

Query: 900  LRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRD 942
             +  ++ L++   E Q ++ +K +EI  L+ ++  ++E  +++
Sbjct: 1413 EQAKKTGLEKEKEELQKVLEKKNEEIRKLKNDYK-KLEKQLKN 1454



 Score = 84.6 bits (200), Expect = 2e-14
 Identities = 170/795 (21%), Positives = 343/795 (43%), Gaps = 98/795 (12%)

Query: 793  YSLERKADQ--LGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKE 850
            Y +E KA    L    +E  +   EY      L+  +   M+ +   EK L  + +   E
Sbjct: 264  YRVEVKAQMKYLSHVKEEMLQKQQEYQKDISGLLTGMKREMEAE--FEKTLDHVHNSQNE 321

Query: 851  LQKKNQILLEENQNL------QISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLE 904
              +K+ +L +E + L         ++D+QQ     +E+A   D    E+ K Q+   DL+
Sbjct: 322  SNQKSLVLQKEVETLTEKLFMSTQINDVQQVKIKNLEQA--LDKVNEENIKLQSSNLDLD 379

Query: 905  ---SNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKK-------VLNEKYEKNI 954
               + L  I  E++ L   +    E L  E     +  +++K          +E+  K  
Sbjct: 380  QVKTELSVIKTENEALRQSQTSGSESLTQEIKLLEQQYLQEKDKNHHLVAAHSEEILKLN 439

Query: 955  EYVTQLEAQLQEYKNNIENLNMNVEELNK-MNLELIDKHVQKQQ-TQSPDYTEQYINEIN 1012
             ++++LE Q+   +  +   ++ V++L K   + L++K+   Q   +     E+   EI 
Sbjct: 440  HHISELEDQIVHIQKELNEKSIQVQQLQKEKEIILVEKNTISQSLVEKETIIEKEKKEIV 499

Query: 1013 KLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLL 1072
             ++++    + E+ +L ++I+  Q S + + S  E +   FT  +E ++ +++   +QL 
Sbjct: 500  HISSV---NESEVHSLREQISKLQ-SEIRLNS--EGQQNDFTALIEALKRDIEEKDQQLK 553

Query: 1073 DSKQHNEELQ----ILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNV 1128
              ++   E+Q    I V E++ Q+  L++ K+   +   K E M++SS +E +  +    
Sbjct: 554  QLREFVMEVQHAGQIKVLEREQQL--LEKDKI---IESQKEELMLLSSKLEQVIREKTFT 608

Query: 1129 DXXXXXXXXXXXXLKVQEEEEFIQERSVLQE-QSAKLN-TELQECYTKIIQ--LETLNTE 1184
                         + V+ + +  QE  V Q+ Q   +   E +E   + ++  +E    +
Sbjct: 609  VSGEIGHVTESVRIDVKSQNKERQETEVKQQVQEIPIEGEEEEEAGVEEVEFDMEVKQAK 668

Query: 1185 LTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLA 1244
             T  +   Q   +Q  S  ++L  EN  +   + + +  +S  V +   +  +  KQ+  
Sbjct: 669  ETRQEGDKQGFFDQASSLSKEL-MENKQVQDNLLKEKDGLSKKVTELNVKYLDAEKQN-N 726

Query: 1245 QREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEE 1304
            ++ A +QK E EL+ Q+   +   ++L   +QS  Q+E  +     ++ +  NK+  K+ 
Sbjct: 727  EKIAQYQKQEAELKQQIQKLQQNVDELTKQIQS--QKEQLQQDADAKLVNETNKI--KQG 782

Query: 1305 HLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQE 1364
            H    Q K   +  +I  L+ ++ +EK                    L+++N S  ++  
Sbjct: 783  H----QAKVIYLNAEIAALKEKLNEEKTQSEQRVSQV----------LQSQNSSSSELIT 828

Query: 1365 QSILNINE--ENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHE 1422
            +  L + E   N  L++                ND E K+++L HQL   + ++  +   
Sbjct: 829  KHELRVTELQNNFNLQR----------------NDLETKIVDLQHQLAALEQKLRDEKSN 872

Query: 1423 YTITLTQR-NDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESE 1481
            +   + Q       ++ +Q   YE ++ +   +K  EL I  +    N+ H +  Q E E
Sbjct: 873  HEALINQNIASNKSSLDEQARGYELKLAE--QQKSYELKITEI----NSKHQQASQ-EVE 925

Query: 1482 IERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEIT 1541
            I   K I EL  +   ++ L ++     K LE+     N  Q A++N  I+   L+ EI 
Sbjct: 926  INYKKQITELQAQSQLNLKLFEERETTTKQLEQ-----NHSQ-AIQN--IKDTHLS-EIN 976

Query: 1542 NLQNMVRASSSKIQK 1556
            NL+N   A  +K+Q+
Sbjct: 977  NLKNQFSADQAKLQQ 991



 Score = 76.6 bits (180), Expect = 5e-12
 Identities = 195/1015 (19%), Positives = 425/1015 (41%), Gaps = 101/1015 (9%)

Query: 147  LSNTIKEKDNALSVL-QVKMKIM---ETTILDLQEKINEKDQIIEAKNKATTXXXXXXXX 202
            L   I+EKD  L  L +  M++    +  +L+ ++++ EKD+IIE++ +           
Sbjct: 541  LKRDIEEKDQQLKQLREFVMEVQHAGQIKVLEREQQLLEKDKIIESQKEELMLLSSKLEQ 600

Query: 203  XXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEA 262
                           +T+     I ++++ K+ ++  +K  + +++ I   EE    +E 
Sbjct: 601  VIREKTFTVSGEIGHVTESVR--IDVKSQNKERQETEVKQ-QVQEIPIEGEEEEEAGVEE 657

Query: 263  ARFEISLEHSK-LAQELEQXXXXXXXXXXXXXXLAKQSIEPSC-EEKTEIEEKGS-LEIA 319
              F++ ++ +K   QE ++              +  + ++ +  +EK  + +K + L + 
Sbjct: 658  VEFDMEVKQAKETRQEGDKQGFFDQASSLSKELMENKQVQDNLLKEKDGLSKKVTELNVK 717

Query: 320  NMT---ELTKKIELLEHLNCQIRQTNKELENKL--ATMGTESKAVSSPSKKGSPLISRKS 374
             +    +  +KI   +    +++Q  ++L+  +   T   +S+         + L++  +
Sbjct: 718  YLDAEKQNNEKIAQYQKQEAELKQQIQKLQQNVDELTKQIQSQKEQLQQDADAKLVNETN 777

Query: 375  GRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTX 434
                  + K  +       L +  +++  ++E  ++  V+QS N      E +   +   
Sbjct: 778  KIKQGHQAKVIYLNAEIAALKEKLNEEKTQSE-QRVSQVLQSQNSS--SSELITKHELRV 834

Query: 435  XXXXXXXXXGKDTLIAQL-QLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEI 493
                      ++ L  ++  L+HQ       L    +N E +  I +     K  L+++ 
Sbjct: 835  TELQNNFNLQRNDLETKIVDLQHQLAALEQKLRDEKSNHEAL--INQNIASNKSSLDEQA 892

Query: 494  KDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDS 553
            +   +K L E+ KS E +IT++N +   A++   +V+ N+K ++ ++Q       K+ + 
Sbjct: 893  RGYELK-LAEQQKSYELKITEINSKHQQASQ---EVEINYKKQITELQAQSQLNLKLFEE 948

Query: 554  NKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRL 613
             +   +  E+ H  SQ +  +++       HL + ++ +   S    K+ +      T+L
Sbjct: 949  RETTTKQLEQNH--SQAIQNIKDT------HLSEINNLKNQFSADQAKLQQENKAVITQL 1000

Query: 614  KA-ISLLESQKFDLVQELHI-LQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDAL 671
            KA I  LE Q  +L Q   I +Q    + + KL  + ++Q  Q  S I+  H        
Sbjct: 1001 KAQIQNLEIQINELNQNHSIQIQNLNKDHQAKLTQV-EVQYKQTISTIEESHKTYISSIQ 1059

Query: 672  SASKKELALVIENLKLDKEQLYGTIKD-LENDKEDIMNKLQNYIQENMDLTDKLEKMSAE 730
               KKE++L  E     K+QL  + +  LE  +     ++ N   E+    ++LEK   +
Sbjct: 1060 ENHKKEISLAEE---ASKKQLNASEQQKLETIENQYKQRINNLESEHKLQIEQLEKQHTQ 1116

Query: 731  KISELLAKINHEEQSKI-QTQFGIDAKIQERDL-YIENIESELSKYKSRICRLEESIAVM 788
            K+S L      + QSKI +T    + KIQE +  Y + I   +S+ +    +   +    
Sbjct: 1117 KVSNL----EKDFQSKIDETIKSYNIKIQEIEKNYSQKIAIVISEKEELSAQNSAASKGQ 1172

Query: 789  EDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDH--------------- 833
            +D+   L+++  +L   ++     + +  I+++E  N L   +                 
Sbjct: 1173 QDKEAQLQKEISELKLKIETLVNNHQKEIIKQEEKYNLLRQTVQQISQNSQNVSVTSNIQ 1232

Query: 834  -----DRVVEKQLLEIEHENKEL---QKKNQILLEENQNLQISLSD----MQQHYNALV- 880
                   V     L ++H+  +L    K+N   ++E + L   L D    ++Q +  L  
Sbjct: 1233 SSSSSSTVNNGDYLVLQHDYNQLIEVNKENLKKIQEERRLYGILQDDYIKLEQQFTTLKN 1292

Query: 881  EKAN---RTDLAESES----TKYQTQLRD---LESNLKRITHEHQTLIVQKKKEIEDLEI 930
            EK N   ++  AES +    T   +QL++    E + +R++ E +  +++ K+E   +  
Sbjct: 1293 EKKNSDKKSKTAESNTAATTTSGASQLKNKAYFEVD-QRVSKELELTVLKLKEENAIIRD 1351

Query: 931  EFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELID 990
            +   + E  I   +    +YEK +  + Q++ +L+  K+  E  +      N  N     
Sbjct: 1352 QLKKEYEDKIYSLEKQAIEYEKKMIELEQVKVELKAMKDEKEEADWEKARKNNGN----- 1406

Query: 991  KHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKL 1050
            K   K++       E+   E+ K   +L++K+EEI    +K+ N        + + ++K 
Sbjct: 1407 KGASKEEQAKKTGLEKEKEELQK---VLEKKNEEI----RKLKNDYKKLEKQLKNLQAKS 1459

Query: 1051 AQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMN 1105
             Q T     +E +    +++    K   +  +I     DD  K  K + + +++N
Sbjct: 1460 PQVTPAPATVESQPTLNTEEAETKKGKKKGYKI----DDDLQKIFKLSDIIYQIN 1510



 Score = 58.8 bits (136), Expect = 1e-06
 Identities = 123/662 (18%), Positives = 277/662 (41%), Gaps = 46/662 (6%)

Query: 954  IEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELID---KHVQKQQTQSPDYTEQYINE 1010
            I Y  +++AQ++   +  E +    +E  K    L+    + ++ +  ++ D+     NE
Sbjct: 262  INYRVEVKAQMKYLSHVKEEMLQKQQEYQKDISGLLTGMKREMEAEFEKTLDHVHNSQNE 321

Query: 1011 INKLNALLKQKDE---EIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRV 1067
             N+ + +L+++ E   E + ++ +IN+ Q   +  +     K+ +   KL++   ++ +V
Sbjct: 322  SNQKSLVLQKEVETLTEKLFMSTQINDVQQVKIKNLEQALDKVNEENIKLQSSNLDLDQV 381

Query: 1068 SKQLLDSKQHNEEL-QILVREQDDQIKELKETKLTFEMNIPKTEGMI---------ISST 1117
              +L   K  NE L Q      +   +E+K  +  +     K   ++         ++  
Sbjct: 382  KTELSVIKTENEALRQSQTSGSESLTQEIKLLEQQYLQEKDKNHHLVAAHSEEILKLNHH 441

Query: 1118 IEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQ 1177
            I  + D   ++             L+ +E+E  + E++ + +   +  T +++   +I+ 
Sbjct: 442  ISELEDQIVHIQKELNEKSIQVQQLQ-KEKEIILVEKNTISQSLVEKETIIEKEKKEIVH 500

Query: 1178 LETLNTELTGHDVVNQEQINQLKSKLEQLNTE--NDNLLSTVAELRSSISSAVDQRGFEI 1235
            + ++N E   H +  +EQI++L+S++ +LN+E   ++  + +  L+  I    DQ+  ++
Sbjct: 501  ISSVN-ESEVHSL--REQISKLQSEI-RLNSEGQQNDFTALIEALKRDIEEK-DQQLKQL 555

Query: 1236 AELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSL 1295
             E   +     +    + E +L  +    ES+ E+L+       Q    K  T+      
Sbjct: 556  REFVMEVQHAGQIKVLEREQQLLEKDKIIESQKEELMLLSSKLEQVIREKTFTVSGEIGH 615

Query: 1296 QNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTE 1355
              +    +   +N + +  +V  Q++ +  E E+E+ A                    T 
Sbjct: 616  VTESVRIDVKSQNKERQETEVKQQVQEIPIEGEEEEEAGVEEVEFDMEVKQAK----ETR 671

Query: 1356 NQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSE 1415
             +  KQ       ++++E  + K+              +V +   K L+   Q   K ++
Sbjct: 672  QEGDKQGFFDQASSLSKELMENKQVQDNLLKEKDGLSKKVTELNVKYLDAEKQNNEKIAQ 731

Query: 1416 IYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYET 1475
             YQK         Q+    +NV +   + + + E L  + +++L     K+ +  +  + 
Sbjct: 732  -YQKQEAELKQQIQKLQ--QNVDELTKQIQSQKEQLQQDADAKLVNETNKI-KQGHQAKV 787

Query: 1476 MQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQ-TALENQ-EIEI 1533
            +   +EI  +K  E+LN + T+S     QV +   +   E+   +E++ T L+N   ++ 
Sbjct: 788  IYLNAEIAALK--EKLNEEKTQSEQRVSQVLQSQNSSSSELITKHELRVTELQNNFNLQR 845

Query: 1534 VTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTM--NKELLDAVPRA-ELD 1590
              L  +I +LQ+ + A   K++       D K   +  ++  +  NK  LD   R  EL 
Sbjct: 846  NDLETKIVDLQHQLAALEQKLR-------DEKSNHEALINQNIASNKSSLDEQARGYELK 898

Query: 1591 LA 1592
            LA
Sbjct: 899  LA 900


>UniRef50_A4S4A9 Cluster: Predicted protein; n=2; Viridiplantae|Rep:
            Predicted protein - Ostreococcus lucimarinus CCE9901
          Length = 3608

 Score =  128 bits (309), Expect = 1e-27
 Identities = 293/1493 (19%), Positives = 609/1493 (40%), Gaps = 136/1493 (9%)

Query: 150  TIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXX 209
            ++ E+  +L   +++    E     LQ+  N+  ++ EA  +                  
Sbjct: 1005 SLLERSISLRAKELQNITSEPQYQRLQKSFNDLKRLSEAAERKLQEKERKIKSLKADSKE 1064

Query: 210  XXEDTK---QQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEAN-KLLEAARF 265
               + K    ++  ++E+   +    K+E+   ++ IES  + + S E A     EA RF
Sbjct: 1065 SAAELKALTSELASVKEDLKYIRDIAKEERDEQIQRIESLMLEVDSFENAKFDGEEAVRF 1124

Query: 266  E---ISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMT 322
                  L   K+  E E               LA+   E         EE  +LE+ ++T
Sbjct: 1125 RNEAAKLRGMKIRLEAE-LKLSQDLAETASSELARAREEHDVVITQLSEEIAALEL-DIT 1182

Query: 323  ELTKKIELLEHLNCQIR-QTNKELENKLATMGT-----ESKAVSSPSKKGSPLISRKSGR 376
              ++ IE LE     I  +   +LE+ LA + T     + K+    S + + +  +++  
Sbjct: 1183 VKSEAIEKLESKTNNIEVKLGSDLESALAKLNTTLEELDKKSTDFASLESASVEQKRNFE 1242

Query: 377  NTASKMKSPW--SQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTX 434
                +++     S+   + L QD D  I   E    EMV + L++  +  + + SE+D  
Sbjct: 1243 KHVDELEKRLGASEAEVQRLIQDRDLAI---EAKDNEMVSKILSQSAIVSD-LESERDAL 1298

Query: 435  XXXXXXXXXGKDTLIAQLQ--LEHQQHMEGPSLIHVGTNTEDVNE-IAKVQEQLKQELND 491
                      +D+ +A ++  LE Q       +  V +  ++    +   ++ L+ EL  
Sbjct: 1299 RSQLADLSSARDSELASVRADLESQLREREEDIERVRSELDESKAALESERDALQSELER 1358

Query: 492  EIKDVNVKD-----LIEKLKSAEEQI-TQLNDEIDAANKNMIKVKSNHKLKLKQMQKTID 545
             +  V   D     ++  L+S  + + +QL D   A +  +  V+++ + +L++ ++ I+
Sbjct: 1359 VLSQVPEVDASQSAIVSDLESERDALRSQLADLSSARDSELASVRADLESQLREREEDIE 1418

Query: 546  NFSKVSDSNKEIVR-----LTEELHHL-----------SQKVAELEEEKGNLQLHLVDYD 589
                  D +K  +      L  EL  +           S  V++LE E+  L+  L D  
Sbjct: 1419 RVRSELDESKAALESERDALQSELERVLSQVPEVDASQSAAVSDLESERDALRSQLADLS 1478

Query: 590  SGRMIESDVYKKMIEMENLAETRLKAI----SLLESQKFDLVQELHILQQKYDEVEDKLA 645
            S R  +S++     ++E+    R + I    S L+  K  L  E   LQ + + V  ++ 
Sbjct: 1479 SAR--DSELASVRADLESQLREREEDIERVRSELDESKAALESERDALQSELERVLSQVP 1536

Query: 646  DISQLQSDQVCSEIKSVH--LEEQI-DALSASKKELALVIENLKLDKEQLYGTIKDLEND 702
            ++   QS  + S+++S    L  Q+ D  SA   ELA V  +L+    QL    +D+E  
Sbjct: 1537 EVDASQS-AIVSDLESERDALRSQLADLSSARDSELASVRADLE---SQLREREEDIERV 1592

Query: 703  KEDIMNKLQNYIQENMDLTDKLEKMSA---EKISELLAKINHEEQSKIQTQFGIDAKIQE 759
            + ++         E   L  +LE++ +   E  +   A ++  E  +   +  +      
Sbjct: 1593 RSELDESKAALESERDALQSELERVLSQVPEVDASQSAAVSDLESERDALRSQLADLSSA 1652

Query: 760  RDLYIENIESEL-SKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTI 818
            RD  + ++ ++L S+ + R   +E   + +++ + +LE + D L S L+       E   
Sbjct: 1653 RDSELASVRADLESQLREREEDIERVRSELDESKAALESERDALQSELERVLSQVPEVDA 1712

Query: 819  QEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNA 878
             +  +V+ L    D    +  QL ++         ++  L     +L+  L + ++    
Sbjct: 1713 SQSAIVSDLESERD---ALRSQLADLS------SARDSELASVRADLESQLREREED--- 1760

Query: 879  LVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIES 938
             +E+  R++L ES++   +++   L+S L+R+  +   +   +   + DLE E +  + S
Sbjct: 1761 -IERV-RSELDESKAA-LESERDALQSELERVLSQVPEVDASQSAAVSDLESERDA-LRS 1816

Query: 939  AIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQT 998
             + D     +    ++     LE+QL+E + +IE +   ++E +K  LE      ++   
Sbjct: 1817 QLADLSSARDSELASVR--ADLESQLREREEDIERVRSELDE-SKAALES-----ERDAL 1868

Query: 999  QSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYE--SKLAQFTTK 1056
            QS    E+ ++++ +++A       ++ +    + + Q++ +S   D E  S  A   ++
Sbjct: 1869 QSE--LERVLSQVPEVDASQSAAVSDLESERDALRS-QLADLSSARDSELASVRADLESQ 1925

Query: 1057 LENMEEEMQRVSKQLLDSKQHNE-ELQILVREQDDQIKELKETKLTFEMNIPKTEGMIIS 1115
            L   EE+++RV  +L +SK   E E   L  E +  + ++ E   +    +   E     
Sbjct: 1926 LREREEDIERVRSELDESKAALESERDALQSELERVLSQVPEVDASQSAAVSDLESE--R 1983

Query: 1116 STIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQE-RSVLQEQSAKLNTELQECYTK 1174
              +     D ++               +++E EE I+  RS L E  A L +E     + 
Sbjct: 1984 DALRSQLADLSSARDSELASVRADLESQLREREEDIERVRSELDESKAALESERDALQS- 2042

Query: 1175 IIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFE 1234
              +LE + +++   D      ++ L+S       E D L S ++ELR   S ++     +
Sbjct: 2043 --ELERVLSQVPEVDASQSAAMSDLES-------ERDALRSQLSELRQMSSESIAGLQQQ 2093

Query: 1235 IAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQ------LLDSVQSSTQEETNKIVT 1288
            +     +  A   A  +KT  EL+  +   E+   +      L D +     E  +K   
Sbjct: 2094 LVAFSAE--ADSAASLRKTVKELKATIRQRENLLSETVFDPMLNDDLDRMNDELASKSAE 2151

Query: 1289 MEQV-TSLQ---NKLQDKEEHLRNLQEKYADVINQIEILRSEI--EDEKVAFXXXXXXXX 1342
            ++   T LQ   NKL+++EE   + Q   + VI++I   R+E+   +EK+A         
Sbjct: 2152 LDSARTKLQSTLNKLKEREEQAESSQAVASAVIDEI---RAELLNANEKLAARESYANAV 2208

Query: 1343 XXXXXXXXDLRTENQSYKQMQEQSIL-NINEENAQLKKSSXXXXXXXXXXXXRVNDAE-A 1400
                      R +  +  +++   IL +   +   L  +              + D E +
Sbjct: 2209 ELALRSELTEREKEIALLRVKVAKILDDSTNKQTSLTTALDSAQSEIERLTRELEDVEQS 2268

Query: 1401 KVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIED------LTYE 1454
            K + +    E  +S+I      +     +  DE +   +     EK + D       T  
Sbjct: 2269 KQVAMKESFERNESQIASLNAAHRELDQRLRDELDAALKAKASLEKELSDRAESTAATET 2328

Query: 1455 KESELAILRLKMHENANHYETMQKESEIERVK----LIEELNVKITESVSLNKQVAELNK 1510
             +     L   +    +   T + E E   VK    L+ EL+    E+ +   + A+L +
Sbjct: 2329 AKRNAEALSESLQSQLDALSTQRAELEQRLVKREEELVAELDAAKHEATAQAARFAQLGE 2388

Query: 1511 ALEEEV-AKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFAS 1562
            A  +    + +++++ +E  E E+  + +E+T+  +  +A  +++   ++ AS
Sbjct: 2389 AASDHAHDEVDKLKSEVERLEFELGAVKNELTSATSTAKADIARLTDELASAS 2441



 Score =  105 bits (253), Expect = 8e-21
 Identities = 258/1341 (19%), Positives = 561/1341 (41%), Gaps = 123/1341 (9%)

Query: 323  ELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKM 382
            EL  K++  +  +    +  + LE++  T+ T+ K+++      +  + + + R    + 
Sbjct: 633  ELLAKLQTAQDQSDTDAEAIRRLEHETETLQTKLKSLTEQLSVANASVEQINSRRFDLE- 691

Query: 383  KSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXX 442
                SQL ++    D     N+ + + +E + + + K+L  +   + ++ +         
Sbjct: 692  ----SQLRAKATELDL-ANANRADTSLVEELRRQV-KNLSTEICWLRDQKSREGSEAEAV 745

Query: 443  XGKDTLIAQLQLEHQQH-MEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEI-KDVNVKD 500
              K    A+ QLE Q++ +E  +   +      ++ I +  E+L  E++++  K +  + 
Sbjct: 746  LQKQLAEARTQLEIQRNELEIEAKAEISELKRSMDVIREEMERLTSEMSEKTEKSLEYQR 805

Query: 501  LIEKLKSAEEQITQLND----EIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVS----D 552
            ++++ +   E +T+  +     ID + KN+ + +   + K K +   +   + +S     
Sbjct: 806  IVQERQKEIESLTKNKELAARAIDESKKNLAQAQEALETKQKALDDRVSQVASLSLDLAA 865

Query: 553  SNKEIVRLTEELHHLSQKVAELEEEKGNLQLH-------LVDYDSGRMIESDVYKKMI-- 603
            S ++ + L  EL    Q+  ELEE   +L+ +       L D D     E+D  + M+  
Sbjct: 866  SEEKTLTLERELSASCQRSQELEELISSLRSYSESRDALLADIDLLLGNENDEREAMLRG 925

Query: 604  -----EMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLA------DISQLQS 652
                 ++    + RL+   +LE +K D  Q L  +    +E++ + A      D+ Q+ S
Sbjct: 926  SKNASDLVERIQKRLRREVVLE-KKLDQAQLLEQVGLTVEELKTREAASLWWKDLVQIGS 984

Query: 653  DQVCSEIKSVHLEEQIDALSAS--KKELALVIENLK-LDKEQLYGTIKDLENDKEDIMNK 709
             +    I+S  ++     ++AS  ++ ++L  + L+ +  E  Y  ++   ND + +   
Sbjct: 985  -KALETIQSTAVDLSKGTVTASLLERSISLRAKELQNITSEPQYQRLQKSFNDLKRLSEA 1043

Query: 710  LQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIES 769
             +  +QE       L+  S E  +EL A  +     K   ++  D   +ERD  I+ IES
Sbjct: 1044 AERKLQEKERKIKSLKADSKESAAELKALTSELASVKEDLKYIRDIAKEERDEQIQRIES 1103

Query: 770  ---ELSKYKS------RICRLEESIAVMEDRRYSLERK----ADQLGSYLQEKQKAYSEY 816
               E+  +++         R     A +   +  LE +     D   +   E  +A  E+
Sbjct: 1104 LMLEVDSFENAKFDGEEAVRFRNEAAKLRGMKIRLEAELKLSQDLAETASSELARAREEH 1163

Query: 817  TIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHY 876
             +   +L   +A L + D  V+ + +E     K   K N I ++   +L+ +L+ +    
Sbjct: 1164 DVVITQLSEEIAAL-ELDITVKSEAIE-----KLESKTNNIEVKLGSDLESALAKLNTTL 1217

Query: 877  NALVEKANRTDLAESEST------KYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEI 930
              L +K+  TD A  ES        ++  + +LE  L     E Q LI  +   IE  + 
Sbjct: 1218 EELDKKS--TDFASLESASVEQKRNFEKHVDELEKRLGASEAEVQRLIQDRDLAIEAKDN 1275

Query: 931  EFNTQI--ESAI-RDKKVLNEKYEKNI-EYVTQLEAQLQEYKNNIEN-LNMNVEELNKMN 985
            E  ++I  +SAI  D +   +     + +  +  +++L   + ++E+ L    E++ ++ 
Sbjct: 1276 EMVSKILSQSAIVSDLESERDALRSQLADLSSARDSELASVRADLESQLREREEDIERVR 1335

Query: 986  LELIDKH--VQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMV 1043
             EL +    ++ ++       E+ ++++ +++A       ++ +    +  +Q++ +S  
Sbjct: 1336 SELDESKAALESERDALQSELERVLSQVPEVDASQSAIVSDLESERDAL-RSQLADLSSA 1394

Query: 1044 SDYE--SKLAQFTTKLENMEEEMQRVSKQLLDSKQHNE-ELQILVREQDDQIKELKETKL 1100
             D E  S  A   ++L   EE+++RV  +L +SK   E E   L  E +  + ++ E   
Sbjct: 1395 RDSELASVRADLESQLREREEDIERVRSELDESKAALESERDALQSELERVLSQVPEVDA 1454

Query: 1101 TFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQE-RSVLQE 1159
            +    +   E       +     D ++               +++E EE I+  RS L E
Sbjct: 1455 SQSAAVSDLESE--RDALRSQLADLSSARDSELASVRADLESQLREREEDIERVRSELDE 1512

Query: 1160 QSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAE 1219
              A L +E     +   +LE + +++   D      ++ L+S       E D L S +A+
Sbjct: 1513 SKAALESERDALQS---ELERVLSQVPEVDASQSAIVSDLES-------ERDALRSQLAD 1562

Query: 1220 LRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSST 1279
            L    SSA D     +    +  L +RE D ++   EL    +A ES+     D++QS  
Sbjct: 1563 L----SSARDSELASVRADLESQLREREEDIERVRSELDESKAALESE----RDALQSEL 1614

Query: 1280 QEETNKIVTMEQVTSLQ-NKLQDKEEHLRN-LQEKYADVINQIEILRSEIEDEKVAFXXX 1337
            +   +++  ++   S   + L+ + + LR+ L +  +   +++  +R+++E +       
Sbjct: 1615 ERVLSQVPEVDASQSAAVSDLESERDALRSQLADLSSARDSELASVRADLESQLREREED 1674

Query: 1338 XXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVND 1397
                          L +E  + +   E+ +  + E +A                    ++
Sbjct: 1675 IERVRSELDESKAALESERDALQSELERVLSQVPEVDA----------SQSAIVSDLESE 1724

Query: 1398 AEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKES 1457
             +A   +L      +DSE+     +    L +R ++ E VR +L E +  +E      +S
Sbjct: 1725 RDALRSQLADLSSARDSELASVRADLESQLREREEDIERVRSELDESKAALESERDALQS 1784

Query: 1458 ELAILRLKMHE----NANHYETMQKESEIERVKLIEELNVKITESVS----LNKQVAELN 1509
            EL  +  ++ E     +     ++ E +  R +L +  + + +E  S    L  Q+ E  
Sbjct: 1785 ELERVLSQVPEVDASQSAAVSDLESERDALRSQLADLSSARDSELASVRADLESQLRERE 1844

Query: 1510 KALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRD 1569
            + +E   ++ +E + ALE++   + +  + + +    V AS S     +    D  + + 
Sbjct: 1845 EDIERVRSELDESKAALESERDALQSELERVLSQVPEVDASQSAAVSDLESERDALRSQL 1904

Query: 1570 EQLDNTMNKELLDAVPRAELD 1590
              L +  + EL  A  RA+L+
Sbjct: 1905 ADLSSARDSEL--ASVRADLE 1923



 Score =  101 bits (242), Expect = 2e-19
 Identities = 284/1594 (17%), Positives = 611/1594 (38%), Gaps = 124/1594 (7%)

Query: 61   LENAALVSKRIKEHRKATAELLGRPFVPGISESLANTLKQKEILMEKIKQYKELSKRSST 120
            LE+A++  KR  E  K   EL  R    G SE+    L Q   L  + K  + +SK  S 
Sbjct: 1230 LESASVEQKRNFE--KHVDELEKRL---GASEAEVQRLIQDRDLAIEAKDNEMVSKILSQ 1284

Query: 121  TIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKIN 180
            + +                QL D++   ++  E  +  + L+ +++  E  I  ++ +++
Sbjct: 1285 SAI---VSDLESERDALRSQLADLSSARDS--ELASVRADLESQLREREEDIERVRSELD 1339

Query: 181  EKDQIIEAKNKATTXXXXXXXXXX----XXXXXXXEDTKQQMTKMQENFIAMEAEWKDEK 236
            E    +E++  A                        D + +   ++     + +    E 
Sbjct: 1340 ESKAALESERDALQSELERVLSQVPEVDASQSAIVSDLESERDALRSQLADLSSARDSEL 1399

Query: 237  QRLLKDIESK-DVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXL 295
              +  D+ES+   R   +E     L+ ++  +  E   L  ELE+               
Sbjct: 1400 ASVRADLESQLREREEDIERVRSELDESKAALESERDALQSELERVLSQVPEVDASQSAA 1459

Query: 296  AKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIEL-LEHLNCQIRQTNKELENKLATMGT 354
                       ++++ +  S   + +  +   +E  L      I +   EL+   A + +
Sbjct: 1460 VSDLESERDALRSQLADLSSARDSELASVRADLESQLREREEDIERVRSELDESKAALES 1519

Query: 355  ESKAVSSPSKKGSPLISRKSGRNTA--SKMKSPWSQLSSETLNQDTDKKINKNEIAKLEM 412
            E  A+ S  ++    +       +A  S ++S    L S+  +  + +    +E+A +  
Sbjct: 1520 ERDALQSELERVLSQVPEVDASQSAIVSDLESERDALRSQLADLSSARD---SELASVRA 1576

Query: 413  VIQS-LNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQ--LEHQQHMEGPSLIHVG 469
             ++S L +   D E V SE D            +D L ++L+  L     ++      V 
Sbjct: 1577 DLESQLREREEDIERVRSELDESKAALESE---RDALQSELERVLSQVPEVDASQSAAVS 1633

Query: 470  TNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKV 529
                + + +      L    + E+  V   DL  +L+  EE I ++  E+D   ++   +
Sbjct: 1634 DLESERDALRSQLADLSSARDSELASVRA-DLESQLREREEDIERVRSELD---ESKAAL 1689

Query: 530  KSNHKLKLKQMQKTIDNFSKVSDSNKEIVR-LTEELHHLSQKVAELEEEKGNLQLHLVDY 588
            +S       ++++ +    +V  S   IV  L  E   L  ++A+L   + + +L  V  
Sbjct: 1690 ESERDALQSELERVLSQVPEVDASQSAIVSDLESERDALRSQLADLSSARDS-ELASVRA 1748

Query: 589  DSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVE-DKLADI 647
            D    +ES + ++  ++E +     ++ + LES++  L  EL  +  +  EV+  + A +
Sbjct: 1749 D----LESQLREREEDIERVRSELDESKAALESERDALQSELERVLSQVPEVDASQSAAV 1804

Query: 648  SQLQSDQVCSEIKSVHLEEQIDA-LSASKKELALVIENLKLDKEQLYGTIKDLENDKEDI 706
            S L+S++     +   L    D+ L++ + +L   +   + D E++   + + +   E  
Sbjct: 1805 SDLESERDALRSQLADLSSARDSELASVRADLESQLREREEDIERVRSELDESKAALESE 1864

Query: 707  MNKLQNYIQENMDLTDKLEKMSAEKISEL----------LAKINHEEQSKIQT-QFGIDA 755
             + LQ+ ++  +    +++   +  +S+L          LA ++    S++ + +  +++
Sbjct: 1865 RDALQSELERVLSQVPEVDASQSAAVSDLESERDALRSQLADLSSARDSELASVRADLES 1924

Query: 756  KIQERDLYIENIESELSKYKSRI--------CRLEESIAVMEDRRYS-------LERKAD 800
            +++ER+  IE + SEL + K+ +          LE  ++ + +   S       LE + D
Sbjct: 1925 QLREREEDIERVRSELDESKAALESERDALQSELERVLSQVPEVDASQSAAVSDLESERD 1984

Query: 801  QLGSYLQEKQKAY-SEYTIQEDELVNRLAVLMDHDRVVEKQLLE----IEHENKELQKKN 855
             L S L +   A  SE      +L ++L    +    V  +L E    +E E   LQ + 
Sbjct: 1985 ALRSQLADLSSARDSELASVRADLESQLREREEDIERVRSELDESKAALESERDALQSEL 2044

Query: 856  QILL----EENQNLQISLSDMQQHYNALVEKANRTDLAESES-TKYQTQL------RDLE 904
            + +L    E + +   ++SD++   +AL  + +      SES    Q QL       D  
Sbjct: 2045 ERVLSQVPEVDASQSAAMSDLESERDALRSQLSELRQMSSESIAGLQQQLVAFSAEADSA 2104

Query: 905  SNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQL 964
            ++L++   E +  I Q++  +   E  F+  +     D   +N++       +     +L
Sbjct: 2105 ASLRKTVKELKATIRQRENLLS--ETVFDPMLND---DLDRMNDELASKSAELDSARTKL 2159

Query: 965  QEYKNNIENLNMNVEELNKMNLELIDKHVQK--QQTQSPDYTEQYINEIN-KLNALLKQK 1021
            Q   N ++      E    +   +ID+   +     +     E Y N +   L + L ++
Sbjct: 2160 QSTLNKLKEREEQAESSQAVASAVIDEIRAELLNANEKLAARESYANAVELALRSELTER 2219

Query: 1022 DEEIIALNQKI-------NNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDS 1074
            ++EI  L  K+        N Q S  + +   +S++ + T +LE++E+  Q   K+  + 
Sbjct: 2220 EKEIALLRVKVAKILDDSTNKQTSLTTALDSAQSEIERLTRELEDVEQSKQVAMKESFER 2279

Query: 1075 KQHN-EELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXX 1133
             +     L    RE D ++++  +  L  + ++ K       ST         N +    
Sbjct: 2280 NESQIASLNAAHRELDQRLRDELDAALKAKASLEKELSDRAEST-AATETAKRNAEALSE 2338

Query: 1134 XXXXXXXXLKVQEEEEFIQERSVLQEQS--AKLNTELQECYTKIIQLETLNTELTGHDVV 1191
                    L  Q  E  +++R V +E+   A+L+    E   +  +   L    + H   
Sbjct: 2339 SLQSQLDALSTQRAE--LEQRLVKREEELVAELDAAKHEATAQAARFAQLGEAASDH--- 2393

Query: 1192 NQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQ 1251
              +++++LKS++E+L  E   + + +    S+  + + +   E+A       A R+A   
Sbjct: 2394 AHDEVDKLKSEVERLEFELGAVKNELTSATSTAKADIARLTDELASA----SAARDA-VA 2448

Query: 1252 KTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQE 1311
            +T H      S   S +E +   +     E    +  + ++ S +       E +R    
Sbjct: 2449 ETAHPEEDGSSESASAFEAMRRDMTRLESELAAALAELAELESPRESESSDTEAIREFTT 2508

Query: 1312 KYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNIN 1371
                  ++IE L  E+ED + +                  L   ++   Q     +    
Sbjct: 2509 ALDSAQSEIERLTRELEDVEQSKQVAMKESFERNESQIASLNAAHRELDQRLRDELDAAL 2568

Query: 1372 EENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSE-------IYQKTHEYT 1424
            +  A L++ S            + N AEA    L  QL+   ++       + ++  E  
Sbjct: 2569 KAKASLEERSDRAESTAATETAKRN-AEALSESLQSQLDALSTQRAELEQRLVKREEELV 2627

Query: 1425 ITLTQRNDEFENVRQQLVEYEKRIEDLTYEK----ESELAILRLKMHENANHYETMQKES 1480
              L     E      +  +  +   D  +++    +SE+  L  ++    N   +    +
Sbjct: 2628 AELDAAKHEATAQAARFAQLGEAASDHAHDEVDKLKSEVERLEFELGAVKNELTSATSTA 2687

Query: 1481 EIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEI 1540
            + +  +L +EL        ++ +          E  +    M+  +   E E+     E+
Sbjct: 2688 KADIARLTDELASASAARDAVAETAHPEEDGSSESASAFEAMRRDMTRLESELAAALAEL 2747

Query: 1541 TNLQNMVRASSSKIQ--KHVSFASDTKQGRDEQL 1572
              L++   + SS  +  +  + A D+ Q   E+L
Sbjct: 2748 AELESPRESESSDTEAIREFTTALDSAQSEIERL 2781



 Score = 97.5 bits (232), Expect = 3e-18
 Identities = 308/1658 (18%), Positives = 648/1658 (39%), Gaps = 139/1658 (8%)

Query: 11   SEMELSEETTARLPSSEVSSVAGXXXXXXXXXXXXXXXERQIKFERAQKCLEN--AALVS 68
            S++E SE    R   +++SS                  ER+   ER +  L+   AAL S
Sbjct: 1977 SDLE-SERDALRSQLADLSSARDSELASVRADLESQLREREEDIERVRSELDESKAALES 2035

Query: 69   KRIKEHRKATAELLGRPFVPGISESLANTLK-QKEILMEKIKQYKELSKRSSTTIVRXXX 127
            +R     +    L   P V     +  + L+ +++ L  ++ + +++S  S   + +   
Sbjct: 2036 ERDALQSELERVLSQVPEVDASQSAAMSDLESERDALRSQLSELRQMSSESIAGLQQQLV 2095

Query: 128  XXXXXXXXXXXXQLGDVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIE 187
                        +   V  L  TI++++N LS       + +  + D  +++N+     E
Sbjct: 2096 AFSAEADSAASLRK-TVKELKATIRQRENLLSET-----VFDPMLNDDLDRMND-----E 2144

Query: 188  AKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKD 247
              +K+                   ++ ++Q    Q    A+  E + E     + + +++
Sbjct: 2145 LASKSAELDSARTKLQSTLNKL--KEREEQAESSQAVASAVIDEIRAELLNANEKLAARE 2202

Query: 248  VRISSLEEA--NKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCE 305
               +++E A  ++L E  + EI+L   K+A+ L+                A+  IE    
Sbjct: 2203 SYANAVELALRSELTEREK-EIALLRVKVAKILDDSTNKQTSLTTALDS-AQSEIERLTR 2260

Query: 306  EKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKL-ATMGTESKAVSSPSK 364
            E  ++E+  S ++A      +    +  LN   R+ ++ L ++L A +  ++      S 
Sbjct: 2261 ELEDVEQ--SKQVAMKESFERNESQIASLNAAHRELDQRLRDELDAALKAKASLEKELSD 2318

Query: 365  KG-SPLISRKSGRNTASKMKSPWSQLSS-ETLNQDTDKKINKNE---IAKLEMVIQSLNK 419
            +  S   +  + RN  +  +S  SQL +  T   + ++++ K E   +A+L+        
Sbjct: 2319 RAESTAATETAKRNAEALSESLQSQLDALSTQRAELEQRLVKREEELVAELDAAKHEATA 2378

Query: 420  DLVD-KEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIH--VGTNTEDVN 476
                  +   +  D             + L  +L     +     S     +   T+++ 
Sbjct: 2379 QAARFAQLGEAASDHAHDEVDKLKSEVERLEFELGAVKNELTSATSTAKADIARLTDELA 2438

Query: 477  EIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLK 536
              +  ++ + +  + E  +    +     ++    +T+L  E+ AA   + +++S  + +
Sbjct: 2439 SASAARDAVAETAHPE--EDGSSESASAFEAMRRDMTRLESELAAALAELAELESPRESE 2496

Query: 537  LKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQ--KVAELEEEKGN----LQLHLVDYDS 590
                +   +  + +  +  EI RLT EL  + Q  +VA  E  + N      L+    + 
Sbjct: 2497 SSDTEAIREFTTALDSAQSEIERLTRELEDVEQSKQVAMKESFERNESQIASLNAAHREL 2556

Query: 591  GRMIESDVYKKMIEMENLAET--RLKAISLLESQKFDLVQELHILQQKYDEVEDKLADIS 648
             + +  ++   +    +L E   R ++ +  E+ K +       LQ + D +  + A++ 
Sbjct: 2557 DQRLRDELDAALKAKASLEERSDRAESTAATETAKRNAEALSESLQSQLDALSTQRAELE 2616

Query: 649  QL---QSDQVCSEIKSVHLEEQIDALS-ASKKELALVIENLKLDKEQLYGTIKDLENDKE 704
            Q    + +++ +E+ +   E    A   A   E A    + ++DK  L   ++ LE +  
Sbjct: 2617 QRLVKREEELVAELDAAKHEATAQAARFAQLGEAASDHAHDEVDK--LKSEVERLEFELG 2674

Query: 705  DIMNKLQNYIQ----ENMDLTDKLEKMSAEKISELLAKINH-EEQSKIQTQFGIDAKIQE 759
             + N+L +       +   LTD+L   SA +  + +A+  H EE    ++    +A    
Sbjct: 2675 AVKNELTSATSTAKADIARLTDELASASAAR--DAVAETAHPEEDGSSESASAFEA--MR 2730

Query: 760  RDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQ 819
            RD+    +ESEL+   + +  LE           ++      L S   E ++   E  ++
Sbjct: 2731 RDM--TRLESELAAALAELAELESPRESESSDTEAIREFTTALDSAQSEIERLTRE--LE 2786

Query: 820  EDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQ----ILLEENQNLQISLSDMQQH 875
            + E   ++A+    +R  E Q+  +   ++EL ++ +      L+   +L+   SD  + 
Sbjct: 2787 DVEQSKQVAMKESFERN-ESQIASLNAAHRELDQRLRDELDAALKAKASLEKERSDRAES 2845

Query: 876  YNALVEKANRTDLAESESTKYQ-----TQLRDLESNLKRITHEHQTLIVQKKKEIEDLEI 930
              A  E A R   A SES + Q     TQ  +LE  L +   E    +   K E      
Sbjct: 2846 -TAATETAKRNAEALSESLQSQLDALSTQRAELEQRLVKREEELVAELDAAKHEATAQAA 2904

Query: 931  EFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVE-ELNKMNLELI 989
             F  Q+  A  D    +++ +K    V +LE +L   KN + +     + ++ ++  EL 
Sbjct: 2905 RF-AQLGEAASDHA--HDEVDKLKSEVERLEFELGAVKNELTSATSTAKADIARLTDELA 2961

Query: 990  DKHVQKQ---QTQSP--DYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVS 1044
                 +    +T  P  D + +  +    +   + + + E+ A   ++   +    S  S
Sbjct: 2962 SASAARDAVAETAHPEEDGSSESASAFEAMRRDMTRLESELAAALAELAELESPRESESS 3021

Query: 1045 DYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNE-ELQILVREQDDQIKELKETKLTFE 1103
            D E+ + +FTT L++ + E++R++++L D +Q  +  ++      + QI  L       +
Sbjct: 3022 DTEA-IREFTTALDSAQSEIERLTRELEDVEQSKQVAMKESFERNESQIASLNAAHRELD 3080

Query: 1104 MNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAK 1163
              +       + +      + ++  +              + E  +   + S  +E  AK
Sbjct: 3081 QRLRDELDAALKAKASLEKELSDRAESTAATEIAKRNAEALSESLQSQLDASRAEE--AK 3138

Query: 1164 LNTELQECYTKII--QLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELR 1221
            L  EL   + ++   ++  L+ E+T     +QE    L        T     +ST+A L 
Sbjct: 3139 LRDELNH-FQELAREEISALHNEITEIKFTSQESQASLGESPWPSIT-----ISTLAGLN 3192

Query: 1222 SSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQE 1281
              +S    + G E  + W +H A      +K+  +   +L   E++YEQ +  +Q S ++
Sbjct: 3193 EMMSRG-SEFGSEGLD-WLEHAAHEVQALEKSVLDATAELELRENEYEQTIAQLQDSVRD 3250

Query: 1282 -ETN-------KIVTMEQVTSLQNKLQDKEEHLRNLQEKYA-----DVINQIEILRSEIE 1328
             ET+           +  V  L +KL +++E L +L+ + A     DV  ++E+  S + 
Sbjct: 3251 AETDLNSQKSLASAALSDVEHLNDKLAERDEELASLRLELANLVSDDVTRELELTISNLR 3310

Query: 1329 DEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQ----------EQSILNINEENAQLK 1378
             +  A                 D R   ++  ++Q          + SI  I+  N +L 
Sbjct: 3311 IQLTAKDNELNGAVASLNDLENDKRAIEEAMSELQAAADMQAARVQTSIEQISSLNVELA 3370

Query: 1379 KSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVR 1438
            K S              + A     E      L +  +  K       L +   + E++R
Sbjct: 3371 KRSAALDASWDNLSHAESRARFAEQERDDVRRLFEERLAVKER----ALRETQGDVEHLR 3426

Query: 1439 QQLVEYEKRIEDLTYEK-ESELAILRLK-MHENANHYETMQKESEIERVKLIEELNVKIT 1496
            Q +   + +++   Y + E+E          E+A+ +E M++    +  +L  EL   + 
Sbjct: 3427 QTVRNLQDKLKAHRYARSETEAGHPEEDGSSESASAFEAMRR----DMTRLESELAAALA 3482

Query: 1497 ESVSLNKQVAELNKALEEEVAKT---NEMQTALENQEIEIVTLNDEITNLQNMVRASSSK 1553
            E       +AEL    E E + T    E  TAL++ + EI  L  E+ +++   + +  +
Sbjct: 3483 E-------LAELESPRESESSDTEAIREFTTALDSAQSEIERLTRELEDVEQSKQVAMKE 3535

Query: 1554 IQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDL 1591
              +       +      +LD  +  E LDA  +A+  L
Sbjct: 3536 SFERNESQIASLNAAHRELDQRLRDE-LDAALKAKASL 3572



 Score = 66.1 bits (154), Expect = 8e-09
 Identities = 185/950 (19%), Positives = 375/950 (39%), Gaps = 96/950 (10%)

Query: 714  IQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSK 773
            I E  D  D  E  S+ +I+EL   I   E    + Q   + K Q  D  I  +E  L K
Sbjct: 525  IVELQDSLDSGEARSSARIAELRGAIESLELKLTRLQ---EEKTQSVDNRIL-LEDRLQK 580

Query: 774  YKSRICRLEESIAVMED----RRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAV 829
                I  + E   V ++     R  LE + +     LQ   +   +    + EL+ +L  
Sbjct: 581  LNLEIDSVRERERVAQEDWQRERLRLEVELEASVKELQTATRTVDDALKAKLELLAKLQT 640

Query: 830  LMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLS-------DMQQHYNALVEK 882
              D      + +  +EHE + LQ K + L E+      S+        D++    A   +
Sbjct: 641  AQDQSDTDAEAIRRLEHETETLQTKLKSLTEQLSVANASVEQINSRRFDLESQLRAKATE 700

Query: 883  -----ANRTDLAESESTKYQTQ--------LRDLES---NLKRITHEHQTLIVQKKKEIE 926
                 ANR D +  E  + Q +        LRD +S   +      + Q    + + EI+
Sbjct: 701  LDLANANRADTSLVEELRRQVKNLSTEICWLRDQKSREGSEAEAVLQKQLAEARTQLEIQ 760

Query: 927  --DLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKM 984
              +LEIE   +I    R   V+ E+ E+    +++   +  EY+  ++     +E L K 
Sbjct: 761  RNELEIEAKAEISELKRSMDVIREEMERLTSEMSEKTEKSLEYQRIVQERQKEIESLTK- 819

Query: 985  NLELIDKHVQKQ-----QTQSPDYTEQ-----YINEINKLNALLKQKDEEIIALNQKIN- 1033
            N EL  + + +      Q Q    T+Q      ++++  L+  L   +E+ + L ++++ 
Sbjct: 820  NKELAARAIDESKKNLAQAQEALETKQKALDDRVSQVASLSLDLAASEEKTLTLERELSA 879

Query: 1034 NAQVS-----YMSMVSDY-ESK---LAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQIL 1084
            + Q S      +S +  Y ES+   LA     L N  +E + + +   ++    E +Q  
Sbjct: 880  SCQRSQELEELISSLRSYSESRDALLADIDLLLGNENDEREAMLRGSKNASDLVERIQKR 939

Query: 1085 VREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKV 1144
            +R +    K+L + +L  ++ +   E     +      D                  L  
Sbjct: 940  LRREVVLEKKLDQAQLLEQVGLTVEELKTREAASLWWKDLVQIGSKALETIQSTAVDLSK 999

Query: 1145 QEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLE 1204
                  + ERS+        N   +  Y +   L+    +L       + ++ + + K++
Sbjct: 1000 GTVTASLLERSISLRAKELQNITSEPQYQR---LQKSFNDLKRLSEAAERKLQEKERKIK 1056

Query: 1205 QLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAF 1264
             L  ++    + +  L S ++S  +   + I ++ K+   +R+   Q+ E  L +++ +F
Sbjct: 1057 SLKADSKESAAELKALTSELASVKEDLKY-IRDIAKE---ERDEQIQRIE-SLMLEVDSF 1111

Query: 1265 E-SKY--EQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQ-- 1319
            E +K+  E+ +     + +    KI    ++   Q+  +     L   +E++  VI Q  
Sbjct: 1112 ENAKFDGEEAVRFRNEAAKLRGMKIRLEAELKLSQDLAETASSELARAREEHDVVITQLS 1171

Query: 1320 --IEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTE----NQSYKQMQEQSILNINEE 1373
              I  L  +I  +  A                 DL +     N + +++ ++S    + E
Sbjct: 1172 EEIAALELDITVKSEAIEKLESKTNNIEVKLGSDLESALAKLNTTLEELDKKSTDFASLE 1231

Query: 1374 NAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQ----LELKDSEIYQKTHEYTITLTQ 1429
            +A +++              R+  +EA+V  L       +E KD+E+  K    +  ++ 
Sbjct: 1232 SASVEQ-KRNFEKHVDELEKRLGASEAEVQRLIQDRDLAIEAKDNEMVSKILSQSAIVSD 1290

Query: 1430 RNDEFENVRQQLVEYEKRIEDLTYEKESELAILRL----KMHENANHYETMQKESEIERV 1485
               E + +R QL        DL+  ++SELA +R     ++ E     E ++ E +  + 
Sbjct: 1291 LESERDALRSQLA-------DLSSARDSELASVRADLESQLREREEDIERVRSELDESKA 1343

Query: 1486 KLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLND-EI---- 1540
             L  E +   +E   +  QV E++ +    V+     + AL +Q  ++ +  D E+    
Sbjct: 1344 ALESERDALQSELERVLSQVPEVDASQSAIVSDLESERDALRSQLADLSSARDSELASVR 1403

Query: 1541 TNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMN--KELLDAVPRAE 1588
             +L++ +R     I++  S   ++K   + + D   +  + +L  VP  +
Sbjct: 1404 ADLESQLREREEDIERVRSELDESKAALESERDALQSELERVLSQVPEVD 1453



 Score = 63.7 bits (148), Expect = 4e-08
 Identities = 226/1146 (19%), Positives = 447/1146 (39%), Gaps = 110/1146 (9%)

Query: 449  IAQL-QLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELND--EIKDVNVKDLIEK- 504
            +A+L +LE  +  E      +   T  ++      E+L +EL D  + K V +K+  E+ 
Sbjct: 2483 LAELAELESPRESESSDTEAIREFTTALDSAQSEIERLTRELEDVEQSKQVAMKESFERN 2542

Query: 505  ------LKSAEEQITQ-LNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEI 557
                  L +A  ++ Q L DE+DAA    +K K++ + +  + + T    +   ++    
Sbjct: 2543 ESQIASLNAAHRELDQRLRDELDAA----LKAKASLEERSDRAESTAATETAKRNAEALS 2598

Query: 558  VRLTEELHHLSQKVAELEEEKGNLQLHLV-DYDSGRMIESDVYKKMIEM-ENLAETRLKA 615
              L  +L  LS + AELE+     +  LV + D+ +   +    +  ++ E  ++     
Sbjct: 2599 ESLQSQLDALSTQRAELEQRLVKREEELVAELDAAKHEATAQAARFAQLGEAASDHAHDE 2658

Query: 616  ISLLESQKFDLVQELHILQQKYDEVEDKL-ADISQLQSDQVCSE-------IKSVHLEEQ 667
            +  L+S+   L  EL  ++ +         ADI++L +D++ S         ++ H EE 
Sbjct: 2659 VDKLKSEVERLEFELGAVKNELTSATSTAKADIARL-TDELASASAARDAVAETAHPEED 2717

Query: 668  IDALSASKKELALVIENLKLDKE--QLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLE 725
              + SAS  E A+  +  +L+ E       + +LE+ +E   +  +  I+E    T  L+
Sbjct: 2718 GSSESASAFE-AMRRDMTRLESELAAALAELAELESPRESESSDTE-AIRE---FTTALD 2772

Query: 726  KMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESI 785
               +E I  L  ++   EQSK   Q  +    +  +  I ++    + ++    RL + +
Sbjct: 2773 SAQSE-IERLTRELEDVEQSK---QVAMKESFERNESQIASLN---AAHRELDQRLRDEL 2825

Query: 786  AVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIE 845
                  + SLE++           + A        + L ++L  L      +E++L++ E
Sbjct: 2826 DAALKAKASLEKERSDRAESTAATETAKRNAEALSESLQSQLDALSTQRAELEQRLVKRE 2885

Query: 846  HE-NKELQ-KKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDL 903
             E   EL   K++   +  +  Q+  +     ++ + +  +  +  E E    + +L   
Sbjct: 2886 EELVAELDAAKHEATAQAARFAQLGEAASDHAHDEVDKLKSEVERLEFELGAVKNELTSA 2945

Query: 904  ESNLK----RITHE------HQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKN 953
             S  K    R+T E       +  + +     ED   E  +  E+  RD   L  +    
Sbjct: 2946 TSTAKADIARLTDELASASAARDAVAETAHPEEDGSSESASAFEAMRRDMTRLESELAAA 3005

Query: 954  IEYVTQLEAQLQEYKNNIE-------NLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQ 1006
            +  + +LE+  +   ++ E        L+    E+ ++  EL D    KQ      + E+
Sbjct: 3006 LAELAELESPRESESSDTEAIREFTTALDSAQSEIERLTRELEDVEQSKQVAMKESF-ER 3064

Query: 1007 YINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQR 1066
              ++I  LNA  ++ D+ +         A+ S    +SD     A       N E   + 
Sbjct: 3065 NESQIASLNAAHRELDQRLRDELDAALKAKASLEKELSDRAESTAATEIAKRNAEALSES 3124

Query: 1067 VSKQLLDSKQHNEEL-------QILVREQDDQI-KELKETKLTF-EMNIPKTEGMIISST 1117
            +  QL  S+    +L       Q L RE+   +  E+ E K T  E      E    S T
Sbjct: 3125 LQSQLDASRAEEAKLRDELNHFQELAREEISALHNEITEIKFTSQESQASLGESPWPSIT 3184

Query: 1118 IEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQ 1177
            I  ++     +             L+    E    E+SVL + +A+L     E    I Q
Sbjct: 3185 ISTLAGLNEMMSRGSEFGSEGLDWLEHAAHEVQALEKSVL-DATAELELRENEYEQTIAQ 3243

Query: 1178 LE----TLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQR-G 1232
            L+       T+L     +    ++ ++   ++L   ++ L S   EL + +S  V +   
Sbjct: 3244 LQDSVRDAETDLNSQKSLASAALSDVEHLNDKLAERDEELASLRLELANLVSDDVTRELE 3303

Query: 1233 FEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVT-MEQ 1291
              I+ L +  L  ++ +       L   L   +   E+ +  +Q++   +  ++ T +EQ
Sbjct: 3304 LTISNL-RIQLTAKDNELNGAVASLN-DLENDKRAIEEAMSELQAAADMQAARVQTSIEQ 3361

Query: 1292 VTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXD 1351
            ++SL  +L  +   L    +  +   ++      E +D +  F                D
Sbjct: 3362 ISSLNVELAKRSAALDASWDNLSHAESRARFAEQERDDVRRLFEERLAVKERALRETQGD 3421

Query: 1352 LRTENQSYKQMQE----------QSILNINEENAQLKKSSX--XXXXXXXXXXXRVNDAE 1399
            +    Q+ + +Q+          ++     EE+   + +S               +  A 
Sbjct: 3422 VEHLRQTVRNLQDKLKAHRYARSETEAGHPEEDGSSESASAFEAMRRDMTRLESELAAAL 3481

Query: 1400 AKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQL--VEYEKRI--EDLTYEK 1455
            A++ EL    E + S+  +   E+T  L     E E + ++L  VE  K++  ++     
Sbjct: 3482 AELAELESPRESESSDT-EAIREFTTALDSAQSEIERLTRELEDVEQSKQVAMKESFERN 3540

Query: 1456 ESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAE-LNKALEE 1514
            ES++A L      NA H E  Q        +L +EL+  +    SL K++++        
Sbjct: 3541 ESQIASL------NAAHRELDQ--------RLRDELDAALKAKASLEKELSDRAESTAAT 3586

Query: 1515 EVAKTN 1520
            E AK N
Sbjct: 3587 ETAKRN 3592


>UniRef50_UPI0000D57874 Cluster: PREDICTED: similar to GRIP and
            coiled-coil domain-containing 2; n=1; Tribolium
            castaneum|Rep: PREDICTED: similar to GRIP and coiled-coil
            domain-containing 2 - Tribolium castaneum
          Length = 1323

 Score =  128 bits (308), Expect = 2e-27
 Identities = 197/1028 (19%), Positives = 442/1028 (42%), Gaps = 86/1028 (8%)

Query: 614  KAISLLESQKFDLV---QELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDA 670
            K I L    K +LV   + L IL QK  + +D L    Q +++++ + +KS    E  DA
Sbjct: 11   KKIVLENLSKEELVKRCERLLILAQKAKQAKDAL----QEENNELKNRLKS----ESGDA 62

Query: 671  LSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAE 730
             +A       +IENL   K Q   TI+DL++    ++NK+QN  Q+   L ++ +++ +E
Sbjct: 63   TTA-------IIENLTQQKLQFVTTIEDLKSQNAALVNKVQNCTQD-ARLCEEKDRLESE 114

Query: 731  KIS--ELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVM 788
             IS    + ++  E +  I     ++ +++E     +N+  E    ++++  LEE+   +
Sbjct: 115  NISYKRQIKRLTDENEQLITHLESLEKQLEE----CKNLGLE---QQNQLLMLEEANQKL 167

Query: 789  --EDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEH 846
              +D           L   L+E +K  +E     +++      L + D+ +     E++ 
Sbjct: 168  RSDDTSDKSAELQTMLSISLEEVKKLQAENNTMREKIDVLKTNLGEKDKNILTIGQELQE 227

Query: 847  ENKELQKKNQILLEENQNLQI--SLSDMQQHYNALVEK-ANRTDLAESESTKYQTQLRDL 903
            + K ++   +I  E  +N+++   L    + Y++ V K A    + +    +    LR L
Sbjct: 228  KLKLVEDLEKIKNESRENVELVEKLKGRLKFYHSKVVKLAGNVKVLKENKNEV---LRLL 284

Query: 904  ESNLKRITHEHQTLIVQKKK---EIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQL 960
            ++   ++    + L V  KK   EI D++++ N++    I   K  N KY K +E   + 
Sbjct: 285  KTYSHQVEEWKEQLGVASKKLCQEISDIKVQ-NSEYHKEIEGLKESNAKYLKQLE-AHKT 342

Query: 961  EAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQ 1020
            + +  +     E ++   ++L + N  L+   +  QQT     T +  + +  L+ L ++
Sbjct: 343  DDEKSKELGEFERISKEHKKLIEENQRLLQLQLDYQQTVE-TLTVEKESLLENLSQLEER 401

Query: 1021 KDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHN-- 1078
              EEI   + +     +   + + + E    ++   +  +EE++    ++L D+KQ N  
Sbjct: 402  HQEEIKVFDDQSKKDTIEIKNRIEENEKICIEYRKVISKLEEDLDLNLRELNDAKQKNYS 461

Query: 1079 ----------EELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNV 1128
                       E QI  +  ++ +K ++E     EMN            +E  ++D+ N 
Sbjct: 462  LQEALEHSKETERQIADKTSEEILKLVQENAQLVEMNRKLQTTRDNCKQVECQTEDSTNS 521

Query: 1129 DXXXXXXXXXXXXLK-VQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTG 1187
            +             + + E  E  Q      E  +KL +  +E   K+   ET   +   
Sbjct: 522  ELEEVVSGLKRENSELLAEMNEMNQALKERGETISKLQSHCEEVMKKLQLYETQANKNVD 581

Query: 1188 HDVVNQEQINQLKSKLEQLNTEND--NLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQ 1245
            +    +E I +L+ ++E+L   +D  +  S +++L++ I +  ++    +   +      
Sbjct: 582  NISQKEEIIKKLEDEIERLKATSDLNSNTSEISDLKNEIENLKERLNSNLDSSYADSECM 641

Query: 1246 READFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTM-EQVTSLQNKLQDKEE 1304
              +   +TE   R  +   E  +E+    +++   +   K+  +  ++   QN+  D ++
Sbjct: 642  STSTISRTEESNR--MKDLEGSWEERYGKLRNLAVKLKGKVRDLSNELVKEQNEKNDIQQ 699

Query: 1305 HLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLR--TENQSYKQM 1362
               +  +  A +  Q + L+ E+++ K                   D +  +EN+    +
Sbjct: 700  KCASNVKTIATLQAQCDKLQDELDENKKQIKEYSARLDSTLAEVSKDKQKLSENEEIITI 759

Query: 1363 QEQSILNINEENAQLK--KSSXXXXXXXXXXXXRVN-----DAEAKVLELTHQLELKDSE 1415
             ++ +  +N+E    +  K                N     + EAK+ +LT  LE K+  
Sbjct: 760  LKKELEELNQEKVTTEAWKKQISGKVSTFRKELEANKVLKKEYEAKIAKLTSDLEAKEQA 819

Query: 1416 IYQKT--HEYT-ITLTQRNDEFEN---VRQQLVEYEKRIEDLTY---EKESELAILRLKM 1466
            +  ++  H+ T  +L   N E +    +  ++ +YE+ +++L+    +K+ E+  L+ ++
Sbjct: 820  LKAESEYHQQTKNSLEHSNIERKKNSVLNLEMQDYERSVKELSQKLEKKQEEINKLKSQL 879

Query: 1467 HENANHYETMQKESEI--ERV-KLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQ 1523
                +    +++++++  ER  ++  E+     E ++  KQ+++L   +  +  K +++ 
Sbjct: 880  ESQKSTTNAVREQNKLLEERAEEMKSEVGATQAEIIACKKQISDLESVMSSKENKIHDLT 939

Query: 1524 TALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDA 1583
              LE    E    N+E++   + V A   K+   +    +  +G+   L  T+ +++ DA
Sbjct: 940  QILETVRSE----NEELSTELSKVIAEHQKVNTSLKSEKENLKGQILGLQQTL-RDVQDA 994

Query: 1584 VPRAELDL 1591
            +   E +L
Sbjct: 995  LKLKEDEL 1002



 Score =  100 bits (240), Expect = 3e-19
 Identities = 235/1148 (20%), Positives = 483/1148 (42%), Gaps = 84/1148 (7%)

Query: 175  LQEKINE-KDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENF--IAMEAE 231
            LQE+ NE K+++      ATT                 ED K Q   +         +A 
Sbjct: 44   LQEENNELKNRLKSESGDATTAIIENLTQQKLQFVTTIEDLKSQNAALVNKVQNCTQDAR 103

Query: 232  WKDEKQRLLKDIESKDVRISSLEEANKLL--EAARFEISLEHSK---LAQELEQXXXXXX 286
              +EK RL  +  S   +I  L + N+ L       E  LE  K   L Q+ +       
Sbjct: 104  LCEEKDRLESENISYKRQIKRLTDENEQLITHLESLEKQLEECKNLGLEQQNQLLMLEEA 163

Query: 287  XXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLE----HLNCQIRQTN 342
                     + +S E        +EE   L+  N T + +KI++L+      +  I    
Sbjct: 164  NQKLRSDDTSDKSAELQTMLSISLEEVKKLQAENNT-MREKIDVLKTNLGEKDKNILTIG 222

Query: 343  KELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKI 402
            +EL+ KL  +    K + + S++   L+ +  GR     +K   S++     N    K+ 
Sbjct: 223  QELQEKLKLVEDLEK-IKNESRENVELVEKLKGR-----LKFYHSKVVKLAGNVKVLKE- 275

Query: 403  NKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGK-DTLIAQLQLEHQQHME 461
            NKNE+ +L        ++  ++  V S+K             +    I  L+  + ++++
Sbjct: 276  NKNEVLRLLKTYSHQVEEWKEQLGVASKKLCQEISDIKVQNSEYHKEIEGLKESNAKYLK 335

Query: 462  GPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDA 521
               L    T+ E   E+ +  E++ +E    I++ N + L++     ++ +  L  E ++
Sbjct: 336  --QLEAHKTDDEKSKELGEF-ERISKEHKKLIEE-NQR-LLQLQLDYQQTVETLTVEKES 390

Query: 522  ANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKV-AELEEEKG- 579
              +N+ +++  H+ ++K      D   K +   K  +   E++    +KV ++LEE+   
Sbjct: 391  LLENLSQLEERHQEEIKVFD---DQSKKDTIEIKNRIEENEKICIEYRKVISKLEEDLDL 447

Query: 580  NL-QLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLE--SQKFDLVQELHILQQK 636
            NL +L+     +  + E+  + K  E +   +T  + + L++  +Q  ++ ++L   +  
Sbjct: 448  NLRELNDAKQKNYSLQEALEHSKETERQIADKTSEEILKLVQENAQLVEMNRKLQTTRDN 507

Query: 637  YDEVEDKLADISQLQSDQVCSEIKSVHLE--EQIDALSASKKELALVIENLK------LD 688
              +VE +  D +  + ++V S +K  + E   +++ ++ + KE    I  L+      + 
Sbjct: 508  CKQVECQTEDSTNSELEEVVSGLKRENSELLAEMNEMNQALKERGETISKLQSHCEEVMK 567

Query: 689  KEQLYGTI--KDLEN--DKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQ 744
            K QLY T   K+++N   KE+I+ KL++ I E +  T  L   ++E IS+L  +I   E 
Sbjct: 568  KLQLYETQANKNVDNISQKEEIIKKLEDEI-ERLKATSDLNSNTSE-ISDLKNEI---EN 622

Query: 745  SKIQTQFGIDAKIQERDLYIENIES---ELSKYKSRICRLEESIAVMEDRRYSLERKADQ 801
             K +    +D+   + +    +  S   E ++ K      EE    + +    L+ K   
Sbjct: 623  LKERLNSNLDSSYADSECMSTSTISRTEESNRMKDLEGSWEERYGKLRNLAVKLKGKVRD 682

Query: 802  LGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEE 861
            L + L ++Q   ++   +    V  +A L      ++ +L E + + KE   +    L E
Sbjct: 683  LSNELVKEQNEKNDIQQKCASNVKTIATLQAQCDKLQDELDENKKQIKEYSARLDSTLAE 742

Query: 862  NQNLQISLSDMQQHYNAL---VEKANRTDLAESE-----STKYQTQLRDLESNLKRITHE 913
                +  LS+ ++    L   +E+ N+  +         S K  T  ++LE+N K +  E
Sbjct: 743  VSKDKQKLSENEEIITILKKELEELNQEKVTTEAWKKQISGKVSTFRKELEAN-KVLKKE 801

Query: 914  HQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVL-NEKYEKNIEYVTQLEAQLQEYKNNIE 972
            ++  I +   ++E  E     + E   + K  L +   E+    V  LE  +Q+Y+ +++
Sbjct: 802  YEAKIAKLTSDLEAKEQALKAESEYHQQTKNSLEHSNIERKKNSVLNLE--MQDYERSVK 859

Query: 973  NLNMNVE----ELNKMNLELIDKHVQKQQTQSPDYTEQYINE-INKLNALLKQKDEEIIA 1027
             L+  +E    E+NK+  +L     QK  T +     + + E   ++ + +     EIIA
Sbjct: 860  ELSQKLEKKQEEINKLKSQL---ESQKSTTNAVREQNKLLEERAEEMKSEVGATQAEIIA 916

Query: 1028 LNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVRE 1087
              ++I++ +    S++S  E+K+   T  LE +  E + +S +L      ++++   ++ 
Sbjct: 917  CKKQISDLE----SVMSSKENKIHDLTQILETVRSENEELSTELSKVIAEHQKVNTSLKS 972

Query: 1088 QDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEE 1147
            + + +K  +   L   +   +    +    ++ + +D  N                V  E
Sbjct: 973  EKENLKG-QILGLQQTLRDVQDALKLKEDELKIVQNDYENYKVRAQSVLRQNQSRDVGLE 1031

Query: 1148 EEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLN 1207
            E+  +E S L  +   L  EL +C T +  L+  N  L         +   + S++E L 
Sbjct: 1032 EKLSEEVSALGVKCEALTAELNKCKTVVDDLKKENEALVHEKSEVLTKYEDVLSEVEDLK 1091

Query: 1208 TENDNLLS----TVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSA 1263
            +  D L +    T+ E   ++ S +      +A+ ++Q L+++E    +   EL+ ++  
Sbjct: 1092 SLYDQLTNKHQQTMIEHSETVRS-LKVHAETLAQCYRQQLSEQEVRHNREIIELQSKIEK 1150

Query: 1264 FESKYEQL 1271
              S   QL
Sbjct: 1151 APSPELQL 1158



 Score = 95.9 bits (228), Expect = 8e-18
 Identities = 236/1144 (20%), Positives = 491/1144 (42%), Gaps = 141/1144 (12%)

Query: 498  VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEI 557
            VK L  +  +  E+I  L   +   +KN++ +      +L++  K +++  K+ + ++E 
Sbjct: 190  VKKLQAENNTMREKIDVLKTNLGEKDKNILTIGQ----ELQEKLKLVEDLEKIKNESREN 245

Query: 558  VRLTEELH-HLSQKVAELEEEKGNLQLHLVDYDSG-RMIE--SDVYKKMIEMENLAETRL 613
            V L E+L   L    +++ +  GN+++   + +   R+++  S   ++  E   +A  +L
Sbjct: 246  VELVEKLKGRLKFYHSKVVKLAGNVKVLKENKNEVLRLLKTYSHQVEEWKEQLGVASKKL 305

Query: 614  -KAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALS 672
             + IS ++ Q  +  +E+  L+      E     + QL++ +   E KS  L E  + +S
Sbjct: 306  CQEISDIKVQNSEYHKEIEGLK------ESNAKYLKQLEAHKTDDE-KSKELGE-FERIS 357

Query: 673  ASKKELALVIENLKLDKEQL--YGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAE 730
               K+  L+ EN +L + QL    T++ L  +KE ++  L    + + +     +  S +
Sbjct: 358  KEHKK--LIEENQRLLQLQLDYQQTVETLTVEKESLLENLSQLEERHQEEIKVFDDQSKK 415

Query: 731  KISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMED 790
               E+  +I   E+  I+ +  I    ++ DL +  +     K  S    LE S    E 
Sbjct: 416  DTIEIKNRIEENEKICIEYRKVISKLEEDLDLNLRELNDAKQKNYSLQEALEHS---KET 472

Query: 791  RRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQL-----LEIE 845
             R   ++ ++++   +QE          Q  E+  +L    D+ + VE Q       E+E
Sbjct: 473  ERQIADKTSEEILKLVQE--------NAQLVEMNRKLQTTRDNCKQVECQTEDSTNSELE 524

Query: 846  HENKELQKKNQILLEE----NQNLQ---ISLSDMQQHYNALVEKANRTDLAESESTKYQT 898
                 L+++N  LL E    NQ L+    ++S +Q H   +++K    +   +++    +
Sbjct: 525  EVVSGLKRENSELLAEMNEMNQALKERGETISKLQSHCEEVMKKLQLYETQANKNVDNIS 584

Query: 899  Q----LRDLESNLKRI-----THEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEK 949
            Q    ++ LE  ++R+      + + + I   K EIE+L+   N+ ++S+  D + ++  
Sbjct: 585  QKEEIIKKLEDEIERLKATSDLNSNTSEISDLKNEIENLKERLNSNLDSSYADSECMSTS 644

Query: 950  YEKNIE---YVTQLEAQLQEYKNNIENLNMNVE-ELNKMNLELIDKHVQKQQTQSPDYTE 1005
                 E    +  LE   +E    + NL + ++ ++  ++ EL+     K+Q +  D  +
Sbjct: 645  TISRTEESNRMKDLEGSWEERYGKLRNLAVKLKGKVRDLSNELV-----KEQNEKNDIQQ 699

Query: 1006 QYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQ 1065
            +  + +  +  L  Q D        K+ +        + +Y ++L    + L  + ++ Q
Sbjct: 700  KCASNVKTIATLQAQCD--------KLQDELDENKKQIKEYSARL---DSTLAEVSKDKQ 748

Query: 1066 RVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDA 1125
            ++S+        NEE+  ++++   +++EL + K+T E    +  G +  ST      +A
Sbjct: 749  KLSE--------NEEIITILKK---ELEELNQEKVTTEAWKKQISGKV--STFR-KELEA 794

Query: 1126 NNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTEL 1185
            N V               ++ +E+ ++  S   +Q+      L+    +  +   LN E+
Sbjct: 795  NKVLKKEYEAKIAKLTSDLEAKEQALKAESEYHQQT---KNSLEHSNIERKKNSVLNLEM 851

Query: 1186 TGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGF--EIAELWKQHL 1243
              +    +  + +L  KLE+   E + L S +   +S+ ++  +Q     E AE  K  +
Sbjct: 852  QDY----ERSVKELSQKLEKKQEEINKLKSQLESQKSTTNAVREQNKLLEERAEEMKSEV 907

Query: 1244 AQREADF---QKTEHELRVQLSAFESKYE---QLLDSVQSSTQE---ETNKIVTMEQV-- 1292
               +A+    +K   +L   +S+ E+K     Q+L++V+S  +E   E +K++   Q   
Sbjct: 908  GATQAEIIACKKQISDLESVMSSKENKIHDLTQILETVRSENEELSTELSKVIAEHQKVN 967

Query: 1293 TSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDL 1352
            TSL+++ ++ +  +  LQ+   DV + +++   E++  +  +                 L
Sbjct: 968  TSLKSEKENLKGQILGLQQTLRDVQDALKLKEDELKIVQNDYENYKVRAQSV-------L 1020

Query: 1353 RTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELK 1412
            R +NQS     E+    ++EE + L                 V+D + +   L H+    
Sbjct: 1021 R-QNQSRDVGLEE---KLSEEVSALGVKCEALTAELNKCKTVVDDLKKENEALVHE---- 1072

Query: 1413 DSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHEN--A 1470
             SE+  K   Y   L++  D  +++  QL    ++    T  + SE  +  LK+H    A
Sbjct: 1073 KSEVLTK---YEDVLSEVED-LKSLYDQLTNKHQQ----TMIEHSE-TVRSLKVHAETLA 1123

Query: 1471 NHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEE---EVAKTNEMQTALE 1527
              Y     E E+   + I EL  KI ++ S   Q+  L    EE     +  N  + A+ 
Sbjct: 1124 QCYRQQLSEQEVRHNREIIELQSKIEKAPSPELQLPPLPMHREEGEGSESTENTSKNAMH 1183

Query: 1528 NQEIEIVTLND---EITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAV 1584
               +E +  +D   EI  L+  +    SK+    +  +DT+Q  D      MNK L + +
Sbjct: 1184 PVPLERLLGSDNDQEIVFLKKQLSEEESKVVHLTALLADTEQ--DLAKHAQMNKLLKEEI 1241

Query: 1585 PRAE 1588
             R +
Sbjct: 1242 RRQQ 1245



 Score = 75.4 bits (177), Expect = 1e-11
 Identities = 160/821 (19%), Positives = 340/821 (41%), Gaps = 58/821 (7%)

Query: 213  DTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVR-----ISSLEEANKLLEAARFEI 267
            +  +++   ++N   +E + +D     L+++ S   R     ++ + E N+ L+     I
Sbjct: 496  EMNRKLQTTRDNCKQVECQTEDSTNSELEEVVSGLKRENSELLAEMNEMNQALKERGETI 555

Query: 268  SLEHSKLAQELEQXXXXXXXXXXXXXXLA-KQSIEPSCEEKTE-IEEKGSLE--IANMTE 323
            S   S   + +++              ++ K+ I    E++ E ++    L    + +++
Sbjct: 556  SKLQSHCEEVMKKLQLYETQANKNVDNISQKEEIIKKLEDEIERLKATSDLNSNTSEISD 615

Query: 324  LTKKIE-LLEHLNCQIRQTNKELE-NKLATMGTESKAVSSPSKKGSPLISRKSGRNTASK 381
            L  +IE L E LN  +  +  + E    +T+    ++      +GS        RN A K
Sbjct: 616  LKNEIENLKERLNSNLDSSYADSECMSTSTISRTEESNRMKDLEGSWEERYGKLRNLAVK 675

Query: 382  MKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXX 441
            +K     LS+E + +  +K   + + A     I +L     DK  +  E D         
Sbjct: 676  LKGKVRDLSNELVKEQNEKNDIQQKCASNVKTIATLQAQC-DK--LQDELDENKKQIKEY 732

Query: 442  XXGKDTLIAQLQLEHQQHMEGPSLIHV-GTNTEDVNEIAKVQEQLKQELNDEIKDVNVKD 500
                D+ +A++  + Q+  E   +I +     E++N+     E  K++++ ++     + 
Sbjct: 733  SARLDSTLAEVSKDKQKLSENEEIITILKKELEELNQEKVTTEAWKKQISGKVSTFRKEL 792

Query: 501  LIEKL--KSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIV 558
               K+  K  E +I +L  +++A  + +      H+     ++ +     K S  N E+ 
Sbjct: 793  EANKVLKKEYEAKIAKLTSDLEAKEQALKAESEYHQQTKNSLEHSNIERKKNSVLNLEMQ 852

Query: 559  RLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISL 618
                 +  LSQK+ + +EE   L+  L   +S +   + V ++   +E  AE     +  
Sbjct: 853  DYERSVKELSQKLEKKQEEINKLKSQL---ESQKSTTNAVREQNKLLEERAEEMKSEVGA 909

Query: 619  LESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKEL 678
             +++     +++  L+      E+K+ D++     Q+   ++S + EE    LS    E 
Sbjct: 910  TQAEIIACKKQISDLESVMSSKENKIHDLT-----QILETVRSEN-EELSTELSKVIAEH 963

Query: 679  ALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAK 738
              V  +LK +KE L G I  L+    D+ + L+  ++E+ +L  K+ +   E        
Sbjct: 964  QKVNTSLKSEKENLKGQILGLQQTLRDVQDALK--LKED-EL--KIVQNDYENYKVRAQS 1018

Query: 739  INHEEQSK-IQTQFGIDAKIQERDLYIENIESELSKYKSRICRL-EESIAVMEDRRYSLE 796
            +  + QS+ +  +  +  ++    +  E + +EL+K K+ +  L +E+ A++ ++   L 
Sbjct: 1019 VLRQNQSRDVGLEEKLSEEVSALGVKCEALTAELNKCKTVVDDLKKENEALVHEKSEVLT 1078

Query: 797  RKADQLGSYLQEKQKAYSEYT-------IQEDELVNRLAVLMDHDRVVEKQLL---EIEH 846
            +  D L S +++ +  Y + T       I+  E V  L V  +      +Q L   E+ H
Sbjct: 1079 KYEDVL-SEVEDLKSLYDQLTNKHQQTMIEHSETVRSLKVHAETLAQCYRQQLSEQEVRH 1137

Query: 847  ENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQL---RDL 903
              + ++ +++I    +  LQ+    M +      E    T          +  L    D 
Sbjct: 1138 NREIIELQSKIEKAPSPELQLPPLPMHREEGEGSESTENTSKNAMHPVPLERLLGSDNDQ 1197

Query: 904  E-SNLKRITHEHQTLIVQKKKEIEDLE------IEFNTQIESAIR--DKKVLNEKYEKNI 954
            E   LK+   E ++ +V     + D E       + N  ++  IR   + V  EK+ +N+
Sbjct: 1198 EIVFLKKQLSEEESKVVHLTALLADTEQDLAKHAQMNKLLKEEIRRQQRSVEREKHAENL 1257

Query: 955  EYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQK 995
            EY+  +  +     +  E   + V  LN + L+L  +  QK
Sbjct: 1258 EYLKNVVFKFVTLHSGDERSRL-VPVLNTI-LKLSPEETQK 1296



 Score = 46.4 bits (105), Expect = 0.007
 Identities = 129/597 (21%), Positives = 244/597 (40%), Gaps = 51/597 (8%)

Query: 147  LSNTIKEKDNALSVLQVKMKIMETTIL-DLQEKINEKDQIIEAKNKATTXXXXXXXXXXX 205
            L  + +E+   L  L VK+K     +  +L ++ NEK+ I + K  +             
Sbjct: 658  LEGSWEERYGKLRNLAVKLKGKVRDLSNELVKEQNEKNDI-QQKCASNVKTIATLQAQCD 716

Query: 206  XXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANK---LLEA 262
                  ++ K+Q+ +      +  AE   +KQ+L ++ E   +    LEE N+     EA
Sbjct: 717  KLQDELDENKKQIKEYSARLDSTLAEVSKDKQKLSENEEIITILKKELEELNQEKVTTEA 776

Query: 263  ARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAK--QSIEPSCEEKTEIEE--KGSLEI 318
             + +IS + S   +ELE               L    ++ E + + ++E  +  K SLE 
Sbjct: 777  WKKQISGKVSTFRKELEANKVLKKEYEAKIAKLTSDLEAKEQALKAESEYHQQTKNSLEH 836

Query: 319  ANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNT 378
            +N+    KK  +L        ++ KEL  KL       K     +K  S L S+KS  N 
Sbjct: 837  SNIER--KKNSVLNLEMQDYERSVKELSQKL------EKKQEEINKLKSQLESQKSTTNA 888

Query: 379  ASK----MKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVD----KEYVISE 430
              +    ++    ++ SE      +    K +I+ LE V+ S    + D     E V SE
Sbjct: 889  VREQNKLLEERAEEMKSEVGATQAEIIACKKQISDLESVMSSKENKIHDLTQILETVRSE 948

Query: 431  KDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQE-QLKQEL 489
             +               +   L+ E +++++G  ++ +     DV +  K++E +LK   
Sbjct: 949  NEELSTELSKVIAEHQKVNTSLKSE-KENLKG-QILGLQQTLRDVQDALKLKEDELKIVQ 1006

Query: 490  ND-EIKDVNVKDLIEKLKSAEEQITQ-LNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNF 547
            ND E   V  + ++ + +S +  + + L++E+ A     +K ++    +L + +  +D+ 
Sbjct: 1007 NDYENYKVRAQSVLRQNQSRDVGLEEKLSEEVSALG---VKCEA-LTAELNKCKTVVDDL 1062

Query: 548  SKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIE-SDVYKKM-IEM 605
             K    N+ +V    E+    + V    E+  +L   L +     MIE S+  + + +  
Sbjct: 1063 KK---ENEALVHEKSEVLTKYEDVLSEVEDLKSLYDQLTNKHQQTMIEHSETVRSLKVHA 1119

Query: 606  ENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSE-----IK 660
            E LA+   + +S  E +    + EL    +K    E +L  +   + +   SE      K
Sbjct: 1120 ETLAQCYRQQLSEQEVRHNREIIELQSKIEKAPSPELQLPPLPMHREEGEGSESTENTSK 1179

Query: 661  SVHLEEQIDALSASKKELALVIENLKLDKEQ-----LYGTIKDLEND--KEDIMNKL 710
            +      ++ L  S  +  +V    +L +E+     L   + D E D  K   MNKL
Sbjct: 1180 NAMHPVPLERLLGSDNDQEIVFLKKQLSEEESKVVHLTALLADTEQDLAKHAQMNKL 1236


>UniRef50_Q23KF2 Cluster: Putative uncharacterized protein; n=1;
            Tetrahymena thermophila SB210|Rep: Putative
            uncharacterized protein - Tetrahymena thermophila SB210
          Length = 1325

 Score =  128 bits (308), Expect = 2e-27
 Identities = 180/918 (19%), Positives = 393/918 (42%), Gaps = 62/918 (6%)

Query: 480  KVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQ 539
            K QE++++ L D + D   K+++E +K   ++  Q N+ ++   ++ +K +   KL LKQ
Sbjct: 401  KQQEEIQKLLQDSMND---KEILENMKQQLKKCKQENEMLE--QRDRMKQEDMQKL-LKQ 454

Query: 540  MQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVY 599
            + +  +  S++ + NK ++    E+  L Q+  E  +   NLQ +    +S  + ++   
Sbjct: 455  LMELSEENSQMRNENKNLIL---EIQELKQQQHEQSQNGVNLQSN----NSYELDQNQNE 507

Query: 600  KKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEI 659
            K     +N          +L  Q  + +  +  L  K+  +   +     L S      I
Sbjct: 508  KSPYSQDNE--------QILNDQAGEDI--ISFLNHKFCNLFYDIEKYQFLDSIYCLPSI 557

Query: 660  KSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNK----LQNYIQ 715
            +   +E+ I   + +  E     +N   D +QL   I  L+   ++I  K    L     
Sbjct: 558  QDKIIEQSIHETNENNSEQINDYQNNNQDNQQLIQQIAGLQQIIDEINQKNLQQLDTINS 617

Query: 716  ENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYK 775
            +N  L ++L K S ++++ L  K +  E   +Q +  I+  +QE   + + +  E  + K
Sbjct: 618  QNQQLQEQLTKNS-DQVASLEQKTS--ENKDLQEK--INQLLQEEKNF-DLLTQENKELK 671

Query: 776  SRICRLEESIAVMEDRRYSLERKADQLGSY---LQEKQKAYSEYTIQEDELVNRLAVLMD 832
             +I  L++    ++  +     K D+LG     LQE+ +   +   + ++  N    L +
Sbjct: 672  QQIQILQQQQEQIQQEQIKNNEKIDELGQKELNLQEQIRQLQQEINELNQKFNNQKQLNE 731

Query: 833  HDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESE 892
               ++++ L +      E++ +N  L E+NQ  Q  +  +QQ  N  +E  N+ +  E  
Sbjct: 732  ESTILQENLQQSLKNIDEIKLENNNLNEQNQQQQEKIKQIQQELNKNIELINQNEKREQN 791

Query: 893  STKYQTQLRDLESNLKRITH-EHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYE 951
                Q ++  L+  +K+IT  ++Q   +  ++   D E + N  +E   + K++  +K +
Sbjct: 792  ---LQDEVDQLQQKIKQITDAQNQQNELHLQQSSSDQE-KINNLLEELEKVKELYEQKSK 847

Query: 952  KNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEI 1011
             N E +  L+ Q+++ +  I  L   +   N+    L+ +  ++Q  +     E  + ++
Sbjct: 848  DNEEKIEVLQQQVKQKQLEINQLEQQINNKNQEIEALMQQSKEEQIKKLQAQLEDNLQKV 907

Query: 1012 NKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQL 1071
            N L + +K  + E     Q+IN  +   + +    + K       +   +++   +   L
Sbjct: 908  NTLQSEIKGLNLETDEQKQQINQFKQKMIELNEILDKK----QVIINQQQQDFNNLKNNL 963

Query: 1072 LDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMII---SSTIEPMSDDANNV 1128
            L+ +Q   +L+  ++E++D+I +L       + N  + E  +    SS    + +    +
Sbjct: 964  LNQEQQANKLEKEIKEKEDKINDLLNQINQAQQNYQEKEENLKQQNSSNQVQLQEYKQQI 1023

Query: 1129 DXXXXXXXXXXXXLKVQEEE-----EFIQERSVLQEQSAKLNTELQECYTKIIQL-ETLN 1182
                         L  Q +E     + I  + +L EQ+ K + +  E   K+  L ++  
Sbjct: 1024 GMLNQKLISLEQQLSDQIDENQNKQKQIDSQKLLHEQNLKESKKHTENLAKVQNLLDSQI 1083

Query: 1183 TELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQH 1242
             E      +N +Q +QLKSK  Q    ++ L  +  +    + +  +Q   +   L +Q 
Sbjct: 1084 KECKKLKEMNNQQEDQLKSKQNQYEKVSEQLKESEKK-NLDLQNQNEQLISQTNILAQQI 1142

Query: 1243 LAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDK 1302
                 A+ Q ++  L+VQ    ES+ +QL+        +   +   + Q+ +  NK Q+ 
Sbjct: 1143 QLLNFAENQNSDLNLKVQ--QLESQIQQLIAENNGLNNQNIEQQNQLSQLNNKLNKFQED 1200

Query: 1303 EEHLRNLQEKYADVINQIEILRSEIED---EKVAFXXXXXXXXXXXXXXXXDLRTENQSY 1359
             ++ +N Q  Y  +I ++   R+ I     E ++F                 +   ++ Y
Sbjct: 1201 NQYFQN-QYTYGQLIQKLLQNRNGISQAMFENISFFMREIHQHIQHQQNNYVIDLYHKVY 1259

Query: 1360 KQMQEQSILNINEENAQL 1377
            + ++ +S L  N+++ Q+
Sbjct: 1260 QNLESES-LQFNQKSEQI 1276



 Score =  124 bits (298), Expect = 3e-26
 Identities = 175/922 (18%), Positives = 420/922 (45%), Gaps = 64/922 (6%)

Query: 214  TKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSK 273
            +KQ + K  E  I    +   E ++ ++D+ +K  +    +E N +L+  ++ IS +  +
Sbjct: 346  SKQIILKGCEQKIKYLNKQLQESKKKIQDLNNKLNKQEKDKEINSILDPNQY-ISDKQQE 404

Query: 274  LAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEH 333
              Q+L Q                KQ ++   +E   +E++  ++  +M +L K++  L  
Sbjct: 405  EIQKLLQDSMNDKEILENM----KQQLKKCKQENEMLEQRDRMKQEDMQKLLKQLMELSE 460

Query: 334  LNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGR-NTASKMKSPWSQLSSE 392
             N Q+R  NK L  ++  +  +       S+ G  L S  S   +     KSP+SQ + +
Sbjct: 461  ENSQMRNENKNLILEIQELKQQQ---HEQSQNGVNLQSNNSYELDQNQNEKSPYSQDNEQ 517

Query: 393  TLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQL 452
             LN               E +I  LN    +  Y I EK             +D +I   
Sbjct: 518  ILNDQAG-----------EDIISFLNHKFCNLFYDI-EKYQFLDSIYCLPSIQDKIIE-- 563

Query: 453  QLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDL---IEKLKSAE 509
            Q  H+ +      I+   N    N+    Q    Q++ DEI   N++ L     + +  +
Sbjct: 564  QSIHETNENNSEQINDYQNNNQDNQQLIQQIAGLQQIIDEINQKNLQQLDTINSQNQQLQ 623

Query: 510  EQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQ 569
            EQ+T+ +D++ +  +   + K   + K+ Q+ +   NF  ++  NKE   L +++  L Q
Sbjct: 624  EQLTKNSDQVASLEQKTSENKDLQE-KINQLLQEEKNFDLLTQENKE---LKQQIQILQQ 679

Query: 570  KVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQE 629
            +  ++++E+      + +     +   +  +++ +  N    +      L  +   L + 
Sbjct: 680  QQEQIQQEQIKNNEKIDELGQKELNLQEQIRQLQQEINELNQKFNNQKQLNEESTILQEN 739

Query: 630  LHILQQKYDEVEDKLADISQLQSDQVCSEIKSV--HLEEQIDALSASKKELALVIENLKL 687
            L    +  DE++ +  ++++ Q+ Q   +IK +   L + I+ ++ ++K      +NL+ 
Sbjct: 740  LQQSLKNIDEIKLENNNLNE-QNQQQQEKIKQIQQELNKNIELINQNEKR----EQNLQD 794

Query: 688  DKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKM--SAEKISELLAKINHEEQS 745
            + +QL   IK +  D ++  N+L  ++Q++    +K+  +    EK+ EL  + + + + 
Sbjct: 795  EVDQLQQKIKQI-TDAQNQQNEL--HLQQSSSDQEKINNLLEELEKVKELYEQKSKDNEE 851

Query: 746  KIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKAD-QLGS 804
            KI+    +  +++++ L I  +E +++     I  L +     + ++   + + + Q  +
Sbjct: 852  KIEV---LQQQVKQKQLEINQLEQQINNKNQEIEALMQQSKEEQIKKLQAQLEDNLQKVN 908

Query: 805  YLQEKQKAYSEYTIQEDELVNRL-AVLMDHDRVVEKQLLEIEHENKELQK-KNQILLEEN 862
             LQ + K  +  T ++ + +N+    +++ + +++K+ + I  + ++    KN +L +E 
Sbjct: 909  TLQSEIKGLNLETDEQKQQINQFKQKMIELNEILDKKQVIINQQQQDFNNLKNNLLNQEQ 968

Query: 863  Q--NLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQ 920
            Q   L+  + + +   N L+ + N+   A+    + +  L+   S+ +    E++  I  
Sbjct: 969  QANKLEKEIKEKEDKINDLLNQINQ---AQQNYQEKEENLKQQNSSNQVQLQEYKQQIGM 1025

Query: 921  KKKEIEDLEIEFNTQI-ESAIRDKKVLNEK--YEKNIEYVTQLEAQLQEYKNNIENLNMN 977
              +++  LE + + QI E+  + K++ ++K  +E+N++   +    L + +N +++    
Sbjct: 1026 LNQKLISLEQQLSDQIDENQNKQKQIDSQKLLHEQNLKESKKHTENLAKVQNLLDSQIKE 1085

Query: 978  VEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQV 1037
             ++L +MN +  D+ ++ +Q Q    +EQ + E  K N  L+ ++E++I+      N   
Sbjct: 1086 CKKLKEMNNQQEDQ-LKSKQNQYEKVSEQ-LKESEKKNLDLQNQNEQLISQ----TNILA 1139

Query: 1038 SYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKE 1097
              + +++  E++ +    K++ +E ++Q++  +       N E Q  + + ++++ + +E
Sbjct: 1140 QQIQLLNFAENQNSDLNLKVQQLESQIQQLIAENNGLNNQNIEQQNQLSQLNNKLNKFQE 1199

Query: 1098 TKLTFEMNIPKTEGMIISSTIE 1119
                F+     T G +I   ++
Sbjct: 1200 DNQYFQNQY--TYGQLIQKLLQ 1219



 Score =  111 bits (268), Expect = 1e-22
 Identities = 201/1022 (19%), Positives = 443/1022 (43%), Gaps = 106/1022 (10%)

Query: 632  ILQQKYDEVEDKLADISQLQSDQ-VCSEIKSVHLEEQIDALSASKKELALVIENLKLDKE 690
            +L Q  +  E++   I+  Q  Q   ++I+ V   +Q   L+ +K +   + E ++   +
Sbjct: 206  VLDQANNSDEEQQNKINYYQGTQNSLNQIEKVRKIDQSYHLAINKSKFGEIQEEMESPMK 265

Query: 691  QLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLE---KMSAEKISELLAKINHEEQSKI 747
            + +G+     N ++ I+NK  N   +  +  D+ E    ++ EK  EL+  +N+ +  K+
Sbjct: 266  EDFGS-----NIQKAIINKNDNLNTDYFNQNDQQEGQFNINLEKQKELIQDLNNLD--KL 318

Query: 748  QTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQ 807
             +        Q + L+ +NIE +L   K    + +    +++      E+K   L   LQ
Sbjct: 319  TSD-------QIKKLF-KNIEEQLHCLKFCYQQNQSKQIILK----GCEQKIKYLNKQLQ 366

Query: 808  EKQKAYSEYT--IQEDELVNRLAVLMDHDRVV-EKQLLEIEHENKELQKKNQILLEENQN 864
            E +K   +    + + E    +  ++D ++ + +KQ  EI+   ++     +IL    +N
Sbjct: 367  ESKKKIQDLNNKLNKQEKDKEINSILDPNQYISDKQQEEIQKLLQDSMNDKEIL----EN 422

Query: 865  LQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQ---- 920
            ++  L   +Q  N ++E+ +R  + + +  K   QL +L     ++ +E++ LI++    
Sbjct: 423  MKQQLKKCKQE-NEMLEQRDR--MKQEDMQKLLKQLMELSEENSQMRNENKNLILEIQEL 479

Query: 921  KKKEIEDLEIEFNTQIESAIRDKKVLNEK--YEKNIEYVTQLEA--QLQEYKNN-IENLN 975
            K+++ E  +   N Q  ++    +  NEK  Y ++ E +   +A   +  + N+   NL 
Sbjct: 480  KQQQHEQSQNGVNLQSNNSYELDQNQNEKSPYSQDNEQILNDQAGEDIISFLNHKFCNLF 539

Query: 976  MNVEELNKMNL-----ELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQ 1030
             ++E+   ++       + DK +++   ++ +   + IN+    N   +Q  ++I  L Q
Sbjct: 540  YDIEKYQFLDSIYCLPSIQDKIIEQSIHETNENNSEQINDYQNNNQDNQQLIQQIAGLQQ 599

Query: 1031 KINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQ-- 1088
             I+      +  +    S+  Q   +L    +++  + ++  ++K   E++  L++E+  
Sbjct: 600  IIDEINQKNLQQLDTINSQNQQLQEQLTKNSDQVASLEQKTSENKDLQEKINQLLQEEKN 659

Query: 1089 -DDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEE 1147
             D   +E KE K   ++   + E +           D                  ++ E 
Sbjct: 660  FDLLTQENKELKQQIQILQQQQEQIQQEQIKNNEKIDELGQKELNLQEQIRQLQQEINEL 719

Query: 1148 EEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLE--- 1204
             +    +  L E+S  L   LQ+    I +++  N  L   +   QE+I Q++ +L    
Sbjct: 720  NQKFNNQKQLNEESTILQENLQQSLKNIDEIKLENNNLNEQNQQQQEKIKQIQQELNKNI 779

Query: 1205 QLNTEND----NLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEH---EL 1257
            +L  +N+    NL   V +L+  I    D +  +  EL   HL Q  +D +K  +   EL
Sbjct: 780  ELINQNEKREQNLQDEVDQLQQKIKQITDAQNQQ-NEL---HLQQSSSDQEKINNLLEEL 835

Query: 1258 RVQLSAFESKY---EQLLDSVQSSTQEETNKIVTMEQVTSLQNK------LQDKEEHLRN 1308
                  +E K    E+ ++ +Q   +++  +I  +EQ  + +N+       Q KEE ++ 
Sbjct: 836  EKVKELYEQKSKDNEEKIEVLQQQVKQKQLEINQLEQQINNKNQEIEALMQQSKEEQIKK 895

Query: 1309 LQEKYADVINQIEILRSEIE------DEKVA----FXXXXXXXXXXXXXXXXDLRTENQS 1358
            LQ +  D + ++  L+SEI+      DE+      F                 +  + Q 
Sbjct: 896  LQAQLEDNLQKVNTLQSEIKGLNLETDEQKQQINQFKQKMIELNEILDKKQVIINQQQQD 955

Query: 1359 YKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQ 1418
            +  ++  ++LN  ++  +L+K              ++N A+    E    L+ ++S    
Sbjct: 956  FNNLKN-NLLNQEQQANKLEKEIKEKEDKINDLLNQINQAQQNYQEKEENLKQQNSSNQV 1014

Query: 1419 KTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQK 1478
            +  EY   +   N +  ++ QQL +     ++   + +S+  +    + E+  H E + K
Sbjct: 1015 QLQEYKQQIGMLNQKLISLEQQLSDQIDENQNKQKQIDSQKLLHEQNLKESKKHTENLAK 1074

Query: 1479 -----ESEIERVKLIEELNVKITESV-SLNKQVAELNKALEEEVAKT------NEM---Q 1523
                 +S+I+  K ++E+N +  + + S   Q  ++++ L+E   K       NE    Q
Sbjct: 1075 VQNLLDSQIKECKKLKEMNNQQEDQLKSKQNQYEKVSEQLKESEKKNLDLQNQNEQLISQ 1134

Query: 1524 TALENQEIEIVTL-NDEITNLQNMVRASSSKIQKHVSFASD------TKQGRDEQLDNTM 1576
            T +  Q+I+++    ++ ++L   V+   S+IQ+ ++  +        +Q +  QL+N +
Sbjct: 1135 TNILAQQIQLLNFAENQNSDLNLKVQQLESQIQQLIAENNGLNNQNIEQQNQLSQLNNKL 1194

Query: 1577 NK 1578
            NK
Sbjct: 1195 NK 1196



 Score =  102 bits (245), Expect = 7e-20
 Identities = 171/884 (19%), Positives = 389/884 (44%), Gaps = 74/884 (8%)

Query: 331  LEHLNCQIRQTNKELENKLATMGTESKAVSSPS-KKGSPLISRKSGRNTASKMKSPWSQL 389
            +++LN Q++++ K++++    +  + K     S    +  IS K        ++   +  
Sbjct: 358  IKYLNKQLQESKKKIQDLNNKLNKQEKDKEINSILDPNQYISDKQQEEIQKLLQDSMNDK 417

Query: 390  SS-ETLNQDTDKKINKNE-IAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDT 447
               E + Q   K   +NE + + + + Q   + L+ +   +SE+++           K+ 
Sbjct: 418  EILENMKQQLKKCKQENEMLEQRDRMKQEDMQKLLKQLMELSEENSQMRNE-----NKNL 472

Query: 448  LIAQLQLEHQQHMEGPSLIHVGTNT-----EDVNEIAKVQEQLKQELNDEIKDVNVKDLI 502
            ++   +L+ QQH +  + +++ +N      ++ NE +   +  +Q LND+  +  +  L 
Sbjct: 473  ILEIQELKQQQHEQSQNGVNLQSNNSYELDQNQNEKSPYSQDNEQILNDQAGEDIISFLN 532

Query: 503  EKLKSAEEQIT--QLNDEIDAANKNMIKV--KSNHKLKLKQMQKTIDNFSKVSDSNKEIV 558
             K  +    I   Q  D I        K+  +S H+      ++ I+++   +  N++++
Sbjct: 533  HKFCNLFYDIEKYQFLDSIYCLPSIQDKIIEQSIHETNENNSEQ-INDYQNNNQDNQQLI 591

Query: 559  RLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISL 618
               +++  L Q + E+ ++  NLQ         + ++  + K   ++ +L +   +   L
Sbjct: 592  ---QQIAGLQQIIDEINQK--NLQQLDTINSQNQQLQEQLTKNSDQVASLEQKTSENKDL 646

Query: 619  LE--SQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKK 676
             E  +Q     +   +L Q+  E++ ++  I Q Q +Q+  E   +   E+ID L   +K
Sbjct: 647  QEKINQLLQEEKNFDLLTQENKELKQQI-QILQQQQEQIQQE--QIKNNEKIDELG--QK 701

Query: 677  ELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDK-LEKMSAEKISEL 735
            EL L  E ++  ++++    +   N K+  +N+    +QEN+  + K ++++  E  +  
Sbjct: 702  ELNLQ-EQIRQLQQEINELNQKFNNQKQ--LNEESTILQENLQQSLKNIDEIKLENNN-- 756

Query: 736  LAKINHEEQSKI-QTQFGIDAKIQ---ERDLYIENIESELSKYKSRICRLEESIAVMEDR 791
            L + N ++Q KI Q Q  ++  I+   + +   +N++ E+ + + +I ++ ++    ++ 
Sbjct: 757  LNEQNQQQQEKIKQIQQELNKNIELINQNEKREQNLQDEVDQLQQKIKQITDA-QNQQNE 815

Query: 792  RYSLERKADQ--LGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQL------LE 843
             +  +  +DQ  + + L+E +K    Y  +  +   ++ VL    +V +KQL       +
Sbjct: 816  LHLQQSSSDQEKINNLLEELEKVKELYEQKSKDNEEKIEVLQQ--QVKQKQLEINQLEQQ 873

Query: 844  IEHENKELQKKNQILLEEN-QNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRD 902
            I ++N+E++   Q   EE  + LQ  L D  Q  N L  +    +L   E  +   Q + 
Sbjct: 874  INNKNQEIEALMQQSKEEQIKKLQAQLEDNLQKVNTLQSEIKGLNLETDEQKQQINQFKQ 933

Query: 903  LESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEA 962
                L  I  + Q +I Q++++  +L+     Q + A + +K + EK +K  + + Q+  
Sbjct: 934  KMIELNEILDKKQVIINQQQQDFNNLKNNLLNQEQQANKLEKEIKEKEDKINDLLNQINQ 993

Query: 963  QLQEYKNNIENL----NMNVEELN--KMNLELIDKHVQKQQTQSPDYTEQYINE------ 1010
              Q Y+   ENL    + N  +L   K  + ++++ +   + Q  D  ++  N+      
Sbjct: 994  AQQNYQEKEENLKQQNSSNQVQLQEYKQQIGMLNQKLISLEQQLSDQIDENQNKQKQIDS 1053

Query: 1011 ---INKLNALLKQKDEEIIALNQKINNAQV----SYMSMVSDYESKLAQFTTKLENMEEE 1063
               +++ N    +K  E +A  Q + ++Q+        M +  E +L     + E + E+
Sbjct: 1054 QKLLHEQNLKESKKHTENLAKVQNLLDSQIKECKKLKEMNNQQEDQLKSKQNQYEKVSEQ 1113

Query: 1064 MQRVSKQLLDSKQHNEEL--QILVREQDDQIKELKETKLT-FEMNIPKTEGMIISSTIEP 1120
            ++   K+ LD +  NE+L  Q  +  Q  Q+    E + +   + + + E  I     E 
Sbjct: 1114 LKESEKKNLDLQNQNEQLISQTNILAQQIQLLNFAENQNSDLNLKVQQLESQIQQLIAEN 1173

Query: 1121 MSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKL 1164
               +  N++             K QE+ ++ Q +    +   KL
Sbjct: 1174 NGLNNQNIEQQNQLSQLNNKLNKFQEDNQYFQNQYTYGQLIQKL 1217



 Score =   99 bits (238), Expect = 5e-19
 Identities = 182/952 (19%), Positives = 405/952 (42%), Gaps = 89/952 (9%)

Query: 701  NDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISE---LLAKINH---EEQSKIQTQFGID 754
            ++K D +NK  + + E  D  D   +   ++ +E   +L + N+   E+Q+KI    G  
Sbjct: 169  SNKNDQLNKSAHQVIEEQDQNDHFSEQEQDEYNENGDVLDQANNSDEEQQNKINYYQGTQ 228

Query: 755  AKIQERDLYIENIES-ELSKYKSRICRLEESI--AVMEDRRYSLER----KADQLGS-YL 806
              + + +   +  +S  L+  KS+   ++E +   + ED   ++++    K D L + Y 
Sbjct: 229  NSLNQIEKVRKIDQSYHLAINKSKFGEIQEEMESPMKEDFGSNIQKAIINKNDNLNTDYF 288

Query: 807  QEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQ 866
             +  +   ++ I  ++    +  L + D++   Q+ ++    +E     +   ++NQ+ Q
Sbjct: 289  NQNDQQEGQFNINLEKQKELIQDLNNLDKLTSDQIKKLFKNIEEQLHCLKFCYQQNQSKQ 348

Query: 867  ISLSDMQQHYNALVEKANRT-DLAESESTKYQTQLRDLESNL----KRITHEHQTLIVQK 921
            I L   +Q    L ++   +    +  + K   Q +D E N      +   + Q   +QK
Sbjct: 349  IILKGCEQKIKYLNKQLQESKKKIQDLNNKLNKQEKDKEINSILDPNQYISDKQQEEIQK 408

Query: 922  --KKEIEDLEI--EFNTQIESAIRDKKVL-------NEKYEKNIEYVTQLEAQLQEYKNN 970
              +  + D EI      Q++   ++ ++L        E  +K ++ + +L  +  + +N 
Sbjct: 409  LLQDSMNDKEILENMKQQLKKCKQENEMLEQRDRMKQEDMQKLLKQLMELSEENSQMRNE 468

Query: 971  IENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLN-----ALLKQKDEEI 1025
             +NL + ++EL +   E     V  Q   S +  +Q  NE +  +      L  Q  E+I
Sbjct: 469  NKNLILEIQELKQQQHEQSQNGVNLQSNNSYE-LDQNQNEKSPYSQDNEQILNDQAGEDI 527

Query: 1026 IA-LNQKINNAQV---SYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEEL 1081
            I+ LN K  N       Y  + S Y     Q     +++ E  +  S+Q+ D + +N++ 
Sbjct: 528  ISFLNHKFCNLFYDIEKYQFLDSIYCLPSIQDKIIEQSIHETNENNSEQINDYQNNNQDN 587

Query: 1082 QILVRE---QDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXX 1138
            Q L+++       I E+ +  L  +++   ++   +   +   SD   +++         
Sbjct: 588  QQLIQQIAGLQQIIDEINQKNLQ-QLDTINSQNQQLQEQLTKNSDQVASLEQKTSENKDL 646

Query: 1139 XXXLK--VQEEEEF---IQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQ 1193
               +   +QEE+ F    QE   L++Q   L  + ++   + I+      EL   ++  Q
Sbjct: 647  QEKINQLLQEEKNFDLLTQENKELKQQIQILQQQQEQIQQEQIKNNEKIDELGQKELNLQ 706

Query: 1194 EQINQLKSKLEQLNTENDNLL-----STVAE--LRSSISSAVDQRGFEIAELWKQHLAQR 1246
            EQI QL+ ++ +LN + +N       ST+ +  L+ S+ + +D+   E   L +Q+  Q+
Sbjct: 707  EQIRQLQQEINELNQKFNNQKQLNEESTILQENLQQSLKN-IDEIKLENNNLNEQNQQQQ 765

Query: 1247 EADFQ-KTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKI---------VTMEQVTSLQ 1296
            E   Q + E    ++L     K EQ L       Q++  +I         + ++Q +S Q
Sbjct: 766  EKIKQIQQELNKNIELINQNEKREQNLQDEVDQLQQKIKQITDAQNQQNELHLQQSSSDQ 825

Query: 1297 NKLQDKEEHLRNLQEKY----ADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDL 1352
             K+ +  E L  ++E Y     D   +IE+L+ +++ +++                   +
Sbjct: 826  EKINNLLEELEKVKELYEQKSKDNEEKIEVLQQQVKQKQLEINQLEQQINNKNQEIEALM 885

Query: 1353 -RTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLEL 1411
             +++ +  K++Q Q   N+ + N  L+               ++N  + K++EL   L+ 
Sbjct: 886  QQSKEEQIKKLQAQLEDNLQKVNT-LQSEIKGLNLETDEQKQQINQFKQKMIELNEILDK 944

Query: 1412 KDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYE-KESELAILRLKMHENA 1470
            K            + + Q+  +F N++  L+  E++   L  E KE E  I  L    N 
Sbjct: 945  KQ-----------VIINQQQQDFNNLKNNLLNQEQQANKLEKEIKEKEDKINDLLNQINQ 993

Query: 1471 NHYETMQKESEIERVKLIEELNV-KITESVS-LNKQVAELNKALEEEVAKTNEMQTALEN 1528
                  +KE  +++     ++ + +  + +  LN+++  L + L +++ +    Q  +++
Sbjct: 994  AQQNYQEKEENLKQQNSSNQVQLQEYKQQIGMLNQKLISLEQQLSDQIDENQNKQKQIDS 1053

Query: 1529 QE-IEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKE 1579
            Q+ +    L +   + +N+ +   + +   +      K+  ++Q D   +K+
Sbjct: 1054 QKLLHEQNLKESKKHTENLAKV-QNLLDSQIKECKKLKEMNNQQEDQLKSKQ 1104



 Score = 37.9 bits (84), Expect = 2.3
 Identities = 76/424 (17%), Positives = 177/424 (41%), Gaps = 37/424 (8%)

Query: 152  KEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXX 211
            K+ +  + VLQ ++K  +  I  L+++IN K+Q IEA  + +                  
Sbjct: 847  KDNEEKIEVLQQQVKQKQLEINQLEQQINNKNQEIEALMQQS------KEEQIKKLQAQL 900

Query: 212  EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISS-LEEANKLLEAARFEIS-- 268
            ED  Q++  +Q     +  E  ++KQ+ +   + K + ++  L++   ++   + + +  
Sbjct: 901  EDNLQKVNTLQSEIKGLNLETDEQKQQ-INQFKQKMIELNEILDKKQVIINQQQQDFNNL 959

Query: 269  ----LEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTEL 324
                L   + A +LE+                 Q+ +   E++  ++++ S     + E 
Sbjct: 960  KNNLLNQEQQANKLEKEIKEKEDKINDLLNQINQAQQNYQEKEENLKQQNSSNQVQLQEY 1019

Query: 325  TKKIELLEH----LNCQIRQTNKELENKLATMGTES---KAVSSPSKKGSPLISR----- 372
             ++I +L      L  Q+     E +NK   + ++    +     SKK +  +++     
Sbjct: 1020 KQQIGMLNQKLISLEQQLSDQIDENQNKQKQIDSQKLLHEQNLKESKKHTENLAKVQNLL 1079

Query: 373  KSGRNTASKMKSPWSQLSSETLN-QDTDKKINK--NEIAKLEMVIQSLNKDLVDKEYVIS 429
             S      K+K   +Q   +  + Q+  +K+++   E  K  + +Q+ N+ L+ +  +++
Sbjct: 1080 DSQIKECKKLKEMNNQQEDQLKSKQNQYEKVSEQLKESEKKNLDLQNQNEQLISQTNILA 1139

Query: 430  EKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLK--Q 487
            ++              +  + QL+ + QQ +   + ++   N E  N+++++  +L   Q
Sbjct: 1140 QQIQLLNFAENQNSDLNLKVQQLESQIQQLIAENNGLN-NQNIEQQNQLSQLNNKLNKFQ 1198

Query: 488  ELNDEIKD-VNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDN 546
            E N   ++      LI+KL      I+Q   E    N +    + +  ++ +Q    ID 
Sbjct: 1199 EDNQYFQNQYTYGQLIQKLLQNRNGISQAMFE----NISFFMREIHQHIQHQQNNYVIDL 1254

Query: 547  FSKV 550
            + KV
Sbjct: 1255 YHKV 1258


>UniRef50_Q16FM5 Cluster: LL5 beta protein, putative; n=2; Aedes
            aegypti|Rep: LL5 beta protein, putative - Aedes aegypti
            (Yellowfever mosquito)
          Length = 2242

 Score =  128 bits (308), Expect = 2e-27
 Identities = 269/1439 (18%), Positives = 570/1439 (39%), Gaps = 115/1439 (7%)

Query: 212  EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271
            E  KQ   + Q    A++ +   +K+ LLK I  KD    +L + N  L      +  EH
Sbjct: 549  ELVKQTANEYQRKNQALDEDVNRQKRDLLKLISEKD----ALSQQNLTLNVEFNSLKGEH 604

Query: 272  SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEE--KTEIEEKGSLEIANMTELTKKIE 329
              L  +++                +        +E  +T  E+K  L   NM    +K+ 
Sbjct: 605  ESLTAKIDYLMLSLNEDYEGSDFSSWFDKMDDLKERVRTLKEDKERLTGMNMKITMEKVG 664

Query: 330  LLEHLNC------QIRQTNKELENKLATMGTE-SKAVSSPSKKGSPLISRKSGRNTASKM 382
            L +H++       ++++ + E E KL  +  + S++  +  +KG+ + S +      + +
Sbjct: 665  LEKHISVSEMRLKEMKELHAESEKKLRRLSEQLSESEKALEEKGNCVTSLE---KLKADL 721

Query: 383  KSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVIS-EKDTXXXXXXXX 441
            +     LS+E L   +       +    E  ++S+  +L  ++  +S  K+T        
Sbjct: 722  EENIQGLSAELLESQSKLNEMSEDFQSCEETLRSVRDELESRDQELSCAKNTIEELQTNL 781

Query: 442  XXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDL 501
               +  L + +QL+ +   E   L     N  DV +    + ++ QE   +++ VN++  
Sbjct: 782  EKQQVELQSAMQLQQETASEKEQL---AVNLTDVQQKLSEESEILQETIKKLEQVNLE-- 836

Query: 502  IEKLKSAEEQITQ--------LNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDS 553
             +KL    + + Q        L ++ +   KN  K   N +L+L+ +Q+ + N +  S  
Sbjct: 837  WQKLTEHRDNLQQDKLILEEALAEQCNELGKNS-KTIQNLELQLQNLQQLLANEADQSKE 895

Query: 554  NKEIV--RLTEELHHL--SQKVAELEEEKGNLQLHLVDYDSGRM--IESDVYKKMIEME- 606
             ++ +  ++  + H L  S+K   +        L  ++   G++  +E     K+  +E 
Sbjct: 896  TQQSLNAQIINQQHQLDASRKEQHILSAANRSLLTGLELVQGKITQLEGQYVSKIGTLEA 955

Query: 607  NLAE-----TRLKAISL--------LESQKFDLVQELHILQQKYD---EVEDKLAD-ISQ 649
             L E     T+L A           LE     +++E  ILQ + D   EVE+ L   + +
Sbjct: 956  KLGEFAALLTKLSAYQFKLRLEKAQLEDNLGKMIREFEILQTENDKLLEVENALQQTVQE 1015

Query: 650  LQSDQVCSEIKSVHLEEQ-------IDALSASKKELALVIENLKLDKEQLYG----TIKD 698
            L+ ++   E +SV LEEQ       +D      KEL      L+ ++ +L G      K+
Sbjct: 1016 LRLEKTAVEERSVGLEEQLAEMEVRVDLNGNRIKELEGSCAELEAERTRLLGDGSQREKE 1075

Query: 699  LENDKEDI---MNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQ-TQFGID 754
            L+   E+      KL+  I++       L+    EK+ +     N  ++ +++  +  +D
Sbjct: 1076 LQKQIEEAAAGSEKLEQEIKQMNKAQSDLQAQLIEKLEQFKCVSNERDEMEVKCARLEVD 1135

Query: 755  AKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYS 814
             K  + DL  E      S  +++   LE  +  + +    LE+   ++   L++ +    
Sbjct: 1136 MKELQADLE-EQKHMTTSNCEAK-AALEAQLLAVREELSQLEQDKSRVEETLEKNRATLE 1193

Query: 815  EYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQ 874
            E T     L     +L +  + +   L  +      +Q+K +   E++  L   L D+  
Sbjct: 1194 ERTETISRLSREKELLSEKVQELATVLATVRQTKSTIQQKLEEQQEKSDELSCQLEDLNS 1253

Query: 875  HYNALVEKANR-TDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFN 933
               A+ E+  R T+  E+   +   + ++L   ++ +T E   +  + +  + + +    
Sbjct: 1254 KLLAVAEELGRVTEEKEAILIRQNAEKQELVEKVEELT-ESIAMAEEDRDTLREEKCRLQ 1312

Query: 934  TQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHV 993
             ++E    DK  L+E+  K ++   QL  + ++  N      + +  L +      ++  
Sbjct: 1313 AEVERIEHDKGSLDEQCGKLLK---QLSKEREDAANEKARQEITIAALGE------ERDA 1363

Query: 994  QKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQK--INNAQVSYMSMVSDYESKLA 1051
             +++  + D  E+      K+  L + K     AL+ K  + +  V    ++ +  S+  
Sbjct: 1364 LQEKLAAID--EERGALAGKVAELEETKTGLECALSDKGAVESKVVELSKLIDELRSEKM 1421

Query: 1052 QFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEG 1111
            +   +  ++ EE+   +K + + K++   L+   +    Q+    ET       +     
Sbjct: 1422 KLEGEWSSLSEELHSNNKTIEELKENVRTLEESKKNLQSQVSNGNETNKQLRQEVQDLSK 1481

Query: 1112 MIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQE-EEEFIQERSVLQEQSAKLNTELQE 1170
             + +S  E    +A  V+             KV+E   E  Q  S LQE  A L T+ +E
Sbjct: 1482 ALQASKQE---IEAMEVETKKLATELTQSEAKVEELSAEIKQTSSQLQEVEAILKTKERE 1538

Query: 1171 CYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQ 1230
                  +L     +L       ++ I Q    +E + TE   L   + ++ +  S+    
Sbjct: 1539 SAVVSEKLVERTKDLELVRSQKEDVILQQSRNIESIQTEQQELAKRLQQVLTESSN---- 1594

Query: 1231 RGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTME 1290
            R  E+ +L  + L  R  + +  E E+  +     S  E L  S   + +   N    ++
Sbjct: 1595 REAEVKQLTGE-LNSRSLELKAKEQEVHAKEQEIRSATELLTASEAKAAELSLN----VD 1649

Query: 1291 QVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXX 1350
            Q+ + ++ L   E  +R LQ+ +       +    + ED   A                 
Sbjct: 1650 QLNAAKSSL---EMQIRKLQDDFDHERELCQATERKAED-LAASLSEASESKIRLEHQLH 1705

Query: 1351 DLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLE 1410
             L  E  + +   +Q I  +++  AQ+ K                   E KV  +   LE
Sbjct: 1706 QLEIERTNAESANQQLIQQLSDLKAQVAKQQTSIDAKDTEIHHLTEGLE-KVKRIQSHLE 1764

Query: 1411 LKDSE---IYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKE--SELAILRLK 1465
             K ++   +  +  E    L +  +E E ++      E  ++ +  EK       I +L+
Sbjct: 1765 EKVTDFESVVTEKDEIETQLIRLQNELETIQDDKRRIETELDAVKEEKADVDRRLIQQLQ 1824

Query: 1466 MHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTA 1525
             ++  N     ++E+  E     + LN K+ E+ + N  +   +++ + ++A   E + A
Sbjct: 1825 NYDTVNEAYRNEREANKELQAKQQNLNKKLQEATAENALLVHTHESSKAQLA-AKEKRIA 1883

Query: 1526 LENQEIEIVTLNDEITNL--QNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLD 1582
             +++++E   L  E+ NL  +N    S +    H+       + + E+L+  + ++ ++
Sbjct: 1884 EQDKQME--KLKREMENLFGKNQQMDSLASEFMHLKVEKSELEAKKEELNEAIEQKEIE 1940



 Score =  127 bits (306), Expect = 3e-27
 Identities = 283/1448 (19%), Positives = 591/1448 (40%), Gaps = 126/1448 (8%)

Query: 169  ETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAM 228
            E  +  L E+++E ++ +E K    T                  +  +  +K+ E  ++ 
Sbjct: 687  EKKLRRLSEQLSESEKALEEKGNCVTSLEKLKADLEENIQGLSAELLESQSKLNE--MSE 744

Query: 229  EAEWKDEKQRLLKD-IESKDVRIS----SLEEANKLLEAARFEISLEHSKLAQELEQXXX 283
            + +  +E  R ++D +ES+D  +S    ++EE    LE  + E+     + A +L+Q   
Sbjct: 745  DFQSCEETLRSVRDELESRDQELSCAKNTIEELQTNLEKQQVEL-----QSAMQLQQETA 799

Query: 284  XXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNK 343
                         +Q +    E   E  +K  LE  N+ E  K  E  ++L        +
Sbjct: 800  SEKEQLAVNLTDVQQKLSEESEILQETIKK--LEQVNL-EWQKLTEHRDNLQQDKLILEE 856

Query: 344  ELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKIN 403
             L  +   +G  SK + +   +   L  ++   N A + K     L+++ +NQ      +
Sbjct: 857  ALAEQCNELGKNSKTIQNLELQLQNL--QQLLANEADQSKETQQSLNAQIINQQHQLDAS 914

Query: 404  KNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGP 463
            + E    + ++ + N+ L+    ++  K T          G  TL A+L  E    +   
Sbjct: 915  RKE----QHILSAANRSLLTGLELVQGKITQLEGQYVSKIG--TLEAKLG-EFAALLTKL 967

Query: 464  SLIHVGTNTEDVNEIAKVQEQLKQELND-EIKDVNVKDLIEKLKSAEEQITQLNDEIDAA 522
            S        E     A++++ L + + + EI       L+E   + ++ + +L  E  A 
Sbjct: 968  SAYQFKLRLEK----AQLEDNLGKMIREFEILQTENDKLLEVENALQQTVQELRLEKTAV 1023

Query: 523  NKNMIKVKSNHKLKLKQMQKTID-NFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNL 581
             +  + ++     +L +M+  +D N +++ +       L  E   L    ++ E+E   L
Sbjct: 1024 EERSVGLEE----QLAEMEVRVDLNGNRIKELEGSCAELEAERTRLLGDGSQREKE---L 1076

Query: 582  QLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVE 641
            Q  + +  +G    S+  ++ I+  N      KA S L++Q  + +++   +  + DE+E
Sbjct: 1077 QKQIEEAAAG----SEKLEQEIKQMN------KAQSDLQAQLIEKLEQFKCVSNERDEME 1126

Query: 642  DKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLEN 701
             K A   +L+ D    E+++  LEEQ    +++ +  A +   L   +E+L      LE 
Sbjct: 1127 VKCA---RLEVDM--KELQA-DLEEQKHMTTSNCEAKAALEAQLLAVREEL----SQLEQ 1176

Query: 702  DKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERD 761
            DK  +   L+       + T+ + ++S EK  ELL++   E  + + T     + IQ++ 
Sbjct: 1177 DKSRVEETLEKNRATLEERTETISRLSREK--ELLSEKVQELATVLATVRQTKSTIQQK- 1233

Query: 762  LYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQED 821
                 +E +  K     C+LE       D    L   A++LG   +EK+        ++ 
Sbjct: 1234 -----LEEQQEKSDELSCQLE-------DLNSKLLAVAEELGRVTEEKEAILIRQNAEKQ 1281

Query: 822  ELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVE 881
            ELV ++  L +   + E+    +  E   LQ + + +  +  +L      + +  +   E
Sbjct: 1282 ELVEKVEELTESIAMAEEDRDTLREEKCRLQAEVERIEHDKGSLDEQCGKLLKQLSKERE 1341

Query: 882  KANRTDLAESESTKYQTQLRD-LESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAI 940
             A      +  +     + RD L+  L  I  E   L   K  E+E    E  T +E A+
Sbjct: 1342 DAANEKARQEITIAALGEERDALQEKLAAIDEERGAL-AGKVAELE----ETKTGLECAL 1396

Query: 941  RDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQS 1000
             DK  +  K  +  + + +L ++  + +    +L+  +   NK  +E + ++V+  +   
Sbjct: 1397 SDKGAVESKVVELSKLIDELRSEKMKLEGEWSSLSEELHSNNK-TIEELKENVRTLEESK 1455

Query: 1001 PDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSM-VSDYESKLAQFTTKLEN 1059
             +   Q  N  N+ N  L+Q+ +++    Q  +  ++  M +      ++L Q   K+E 
Sbjct: 1456 KNLQSQVSNG-NETNKQLRQEVQDLSKALQA-SKQEIEAMEVETKKLATELTQSEAKVEE 1513

Query: 1060 MEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMII--SST 1117
            +  E+++ S QL   ++    L+   RE     ++L E     E+   + E +I+  S  
Sbjct: 1514 LSAEIKQTSSQL---QEVEAILKTKERESAVVSEKLVERTKDLELVRSQKEDVILQQSRN 1570

Query: 1118 IEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQ 1177
            IE +  +   +                  E E  Q    L  +S +L  + QE + K  +
Sbjct: 1571 IESIQTEQQELAKRLQQVLTESS----NREAEVKQLTGELNSRSLELKAKEQEVHAKEQE 1626

Query: 1178 LETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAE 1237
            + +    LT     ++ +  +L   ++QLN    +L   + +L+       ++   +  E
Sbjct: 1627 IRSATELLTA----SEAKAAELSLNVDQLNAAKSSLEMQIRKLQDDFDH--ERELCQATE 1680

Query: 1238 LWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTME-QVTSLQ 1296
               + LA   ++  +++  L  QL   E +      + +S+ Q+   ++  ++ QV   Q
Sbjct: 1681 RKAEDLAASLSEASESKIRLEHQLHQLEIERT----NAESANQQLIQQLSDLKAQVAKQQ 1736

Query: 1297 NKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTEN 1356
              +  K+  + +L E     + +++ ++S +E EKV                   L+ E 
Sbjct: 1737 TSIDAKDTEIHHLTEG----LEKVKRIQSHLE-EKVTDFESVVTEKDEIETQLIRLQNEL 1791

Query: 1357 QSY---KQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKD 1413
            ++    K+  E  +  + EE A + +               VN+A     E   +L+ K 
Sbjct: 1792 ETIQDDKRRIETELDAVKEEKADVDRRLIQQLQNYDT----VNEAYRNEREANKELQAKQ 1847

Query: 1414 SEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHY 1473
              + +K  E T          E+ + QL   EKRI     E++ ++  L+ +M EN    
Sbjct: 1848 QNLNKKLQEATAENALLVHTHESSKAQLAAKEKRIA----EQDKQMEKLKREM-ENL--- 1899

Query: 1474 ETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEI 1533
                K  +++ +   E +++K+ +S  L  +  ELN+A+E++  +   MQ ++E+ +  +
Sbjct: 1900 --FGKNQQMDSLAS-EFMHLKVEKS-ELEAKKEELNEAIEQKEIEEKAMQESMEHLKESL 1955

Query: 1534 VTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDLAM 1593
                 E+ +L + V      +       S  K   + QL   +N EL +A    +++   
Sbjct: 1956 KVKQQELDSLHSDVTNLKESLHSLKIENSKLKSTHELQLTKMLNLELKNAEQSKKIEKLE 2015

Query: 1594 YMLHQRDV 1601
              L++ ++
Sbjct: 2016 ESLNKTEI 2023



 Score =  121 bits (292), Expect = 1e-25
 Identities = 232/1174 (19%), Positives = 477/1174 (40%), Gaps = 89/1174 (7%)

Query: 473  EDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSN 532
            E V + A   ++  Q L++++     +DL+ KL S ++ ++Q N  ++    ++     +
Sbjct: 549  ELVKQTANEYQRKNQALDEDVNRQK-RDLL-KLISEKDALSQQNLTLNVEFNSLKGEHES 606

Query: 533  HKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGR 592
               K+  +  +++   + SD +       +++  L ++V  L+E+K  L        +G 
Sbjct: 607  LTAKIDYLMLSLNEDYEGSDFSSWF----DKMDDLKERVRTLKEDKERL--------TGM 654

Query: 593  MIESDVYKKMIEME-NLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQ 651
             ++  + K  +E   +++E RLK +  L ++     ++L  L ++  E E  L +     
Sbjct: 655  NMKITMEKVGLEKHISVSEMRLKEMKELHAES---EKKLRRLSEQLSESEKALEEKGNCV 711

Query: 652  SDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQ 711
            +     ++K+  LEE I  LSA   E    +  +  D +    T++ + ++ E    +L 
Sbjct: 712  TS--LEKLKA-DLEENIQGLSAELLESQSKLNEMSEDFQSCEETLRSVRDELESRDQELS 768

Query: 712  NYIQENMDLTDKLEKMSAEKIS--ELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIES 769
                   +L   LEK   E  S  +L  +   E++        +  K+ E    ++    
Sbjct: 769  CAKNTIEELQTNLEKQQVELQSAMQLQQETASEKEQLAVNLTDVQQKLSEESEILQETIK 828

Query: 770  ELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAV 829
            +L +      +L E    ++  +  LE    +  + L +  K      +Q   L   LA 
Sbjct: 829  KLEQVNLEWQKLTEHRDNLQQDKLILEEALAEQCNELGKNSKTIQNLELQLQNLQQLLAN 888

Query: 830  LMDHDRVVEK----QLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNAL----VE 881
              D  +  ++    Q++  +H+    +K+  IL   N++L   L  +Q     L    V 
Sbjct: 889  EADQSKETQQSLNAQIINQQHQLDASRKEQHILSAANRSLLTGLELVQGKITQLEGQYVS 948

Query: 882  KANRTD--LAE-----SESTKYQTQLR----DLESNLKRITHEHQTLIVQKKKEIEDLEI 930
            K    +  L E     ++ + YQ +LR     LE NL ++  E + L  +  K +E +E 
Sbjct: 949  KIGTLEAKLGEFAALLTKLSAYQFKLRLEKAQLEDNLGKMIREFEILQTENDKLLE-VEN 1007

Query: 931  EFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELI- 989
                 ++    +K  + E+     E + ++E ++    N I+ L  +  EL      L+ 
Sbjct: 1008 ALQQTVQELRLEKTAVEERSVGLEEQLAEMEVRVDLNGNRIKELEGSCAELEAERTRLLG 1067

Query: 990  -----DKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVS 1044
                 +K +QKQ  ++   +E+   EI ++N        ++I   +K+   Q   +S   
Sbjct: 1068 DGSQREKELQKQIEEAAAGSEKLEQEIKQMNKAQSDLQAQLI---EKLE--QFKCVSNER 1122

Query: 1045 D-YESKLAQFTTKLENME---EEMQRVSKQLLDSKQHNEELQILVREQDDQIKELK-ETK 1099
            D  E K A+    ++ ++   EE + ++    ++K   E   + VRE+  Q+++ K   +
Sbjct: 1123 DEMEVKCARLEVDMKELQADLEEQKHMTTSNCEAKAALEAQLLAVREELSQLEQDKSRVE 1182

Query: 1100 LTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQE 1159
             T E N    E    + TI  +S +   +             ++ Q +    Q+    QE
Sbjct: 1183 ETLEKNRATLEER--TETISRLSREKELLSEKVQELATVLATVR-QTKSTIQQKLEEQQE 1239

Query: 1160 QSAKLNTELQECYTKIIQL-ETLN--TELTGHDVVNQ--------EQINQLKSKLEQLNT 1208
            +S +L+ +L++  +K++ + E L   TE     ++ Q        E++ +L   +     
Sbjct: 1240 KSDELSCQLEDLNSKLLAVAEELGRVTEEKEAILIRQNAEKQELVEKVEELTESIAMAEE 1299

Query: 1209 ENDNLLSTVAELRSSISSAVDQRGF---EIAELWKQHLAQRE-ADFQKTEHELRV-QLSA 1263
            + D L      L++ +      +G    +  +L KQ   +RE A  +K   E+ +  L  
Sbjct: 1300 DRDTLREEKCRLQAEVERIEHDKGSLDEQCGKLLKQLSKEREDAANEKARQEITIAALGE 1359

Query: 1264 FESKYEQLLDSVQSSTQEETNKIVTMEQV-TSLQNKLQDKEEHLRNLQEKYADVINQIEI 1322
                 ++ L ++         K+  +E+  T L+  L DK      ++ K  ++   I+ 
Sbjct: 1360 ERDALQEKLAAIDEERGALAGKVAELEETKTGLECALSDKGA----VESKVVELSKLIDE 1415

Query: 1323 LRSE---IEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKK 1379
            LRSE   +E E  +                 ++RT  +S K +Q Q + N NE N QL++
Sbjct: 1416 LRSEKMKLEGEWSSLSEELHSNNKTIEELKENVRTLEESKKNLQSQ-VSNGNETNKQLRQ 1474

Query: 1380 SSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQ 1439
                           +   E +  +L  +L   ++++ + + E   T +Q   E E + +
Sbjct: 1475 EVQDLSKALQASKQEIEAMEVETKKLATELTQSEAKVEELSAEIKQTSSQL-QEVEAILK 1533

Query: 1440 QLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESV 1499
                    + +   E+  +L ++R +  +         +  + E+ +L + L   +TES 
Sbjct: 1534 TKERESAVVSEKLVERTKDLELVRSQKEDVILQQSRNIESIQTEQQELAKRLQQVLTESS 1593

Query: 1500 SLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKI-QKHV 1558
            +   +V +L   L     +    +  +  +E EI +  + +T  +      S  + Q + 
Sbjct: 1594 NREAEVKQLTGELNSRSLELKAKEQEVHAKEQEIRSATELLTASEAKAAELSLNVDQLNA 1653

Query: 1559 SFASDTKQGRDEQLDNTMNKELLDAVPRAELDLA 1592
            + +S   Q R  Q D    +EL  A  R   DLA
Sbjct: 1654 AKSSLEMQIRKLQDDFDHERELCQATERKAEDLA 1687



 Score =  121 bits (292), Expect = 1e-25
 Identities = 217/1113 (19%), Positives = 468/1113 (42%), Gaps = 83/1113 (7%)

Query: 212  EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271
            E+      K+++    M     D + +L++ +E    +  S E     ++ AR E+ ++ 
Sbjct: 1081 EEAAAGSEKLEQEIKQMNKAQSDLQAQLIEKLEQ--FKCVSNERDEMEVKCARLEVDMK- 1137

Query: 272  SKLAQELEQXXXXXXXXXXXXXXL------AKQSIEPSCEEKTEIEEKGSLEIANMTELT 325
             +L  +LE+              L       ++ +    ++K+ +EE      A + E T
Sbjct: 1138 -ELQADLEEQKHMTTSNCEAKAALEAQLLAVREELSQLEQDKSRVEETLEKNRATLEERT 1196

Query: 326  KKIELLEHLNCQIRQTNKELENKLATM----GTESKAVSSPSKKGSPLISRKSGRNTASK 381
            + I  L      + +  +EL   LAT+     T  + +    +K   L  +    N  SK
Sbjct: 1197 ETISRLSREKELLSEKVQELATVLATVRQTKSTIQQKLEEQQEKSDELSCQLEDLN--SK 1254

Query: 382  MKSPWSQLSSETLNQDT---DKKINKNEIA-KLEMVIQSLNKDLVDKEYVISEKDTXXXX 437
            + +   +L   T  ++     +   K E+  K+E + +S+     D++ +  EK      
Sbjct: 1255 LLAVAEELGRVTEEKEAILIRQNAEKQELVEKVEELTESIAMAEEDRDTLREEKCRLQAE 1314

Query: 438  XXXXXXGKDTLIAQL-QLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDV 496
                   K +L  Q  +L  Q   E     +     E    IA + E+ +  L +++  +
Sbjct: 1315 VERIEHDKGSLDEQCGKLLKQLSKEREDAANEKARQEIT--IAALGEE-RDALQEKLAAI 1371

Query: 497  NVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNF-SKVSDSNK 555
            + +      K AE + T+   E   ++K  ++ K      + ++ K ID   S+      
Sbjct: 1372 DEERGALAGKVAELEETKTGLECALSDKGAVESK------VVELSKLIDELRSEKMKLEG 1425

Query: 556  EIVRLTEELH-------HLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENL 608
            E   L+EELH        L + V  LEE K NLQ  +    +G      + +++ ++   
Sbjct: 1426 EWSSLSEELHSNNKTIEELKENVRTLEESKKNLQSQV---SNGNETNKQLRQEVQDLSKA 1482

Query: 609  AETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADIS-QLQSDQVCSEIKSVHLEEQ 667
             +   + I  +E +   L  EL   + K +E+  ++   S QLQ  +   + K       
Sbjct: 1483 LQASKQEIEAMEVETKKLATELTQSEAKVEELSAEIKQTSSQLQEVEAILKTKERESAVV 1542

Query: 668  IDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKM 727
             + L    K+L LV    +    Q    I+ ++ +++++  +LQ  + E+ +   +++++
Sbjct: 1543 SEKLVERTKDLELVRSQKEDVILQQSRNIESIQTEQQELAKRLQQVLTESSNREAEVKQL 1602

Query: 728  SAEKIS---ELLAKIN--HEEQSKIQTQFGI----DAKIQERDLYIENIESELSKYKSRI 778
            + E  S   EL AK    H ++ +I++   +    +AK  E  L ++ + +  S  + +I
Sbjct: 1603 TGELNSRSLELKAKEQEVHAKEQEIRSATELLTASEAKAAELSLNVDQLNAAKSSLEMQI 1662

Query: 779  CRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVE 838
             +L++      +   + ERKA+ L + L E     SE  I+ +  +++L +   +     
Sbjct: 1663 RKLQDDFDHERELCQATERKAEDLAASLSEA----SESKIRLEHQLHQLEIERTNAESAN 1718

Query: 839  KQLLEIEHENKELQKKNQILLE----ENQNLQISLSDMQQHYNALVEKANRTDLAESEST 894
            +QL++   + K    K Q  ++    E  +L   L  +++  + L EK    +   +E  
Sbjct: 1719 QQLIQQLSDLKAQVAKQQTSIDAKDTEIHHLTEGLEKVKRIQSHLEEKVTDFESVVTEKD 1778

Query: 895  KYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNI 954
            + +TQL  L++ L+ I  + +  I  +   +++ + + + ++   +++   +NE Y    
Sbjct: 1779 EIETQLIRLQNELETIQDDKRR-IETELDAVKEEKADVDRRLIQQLQNYDTVNEAYRNER 1837

Query: 955  EYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKL 1014
            E   +L+A+ Q       NLN  ++E    N  L+  H   +   +    E+ I E +K 
Sbjct: 1838 EANKELQAKQQ-------NLNKKLQEATAENALLVHTHESSKAQLAAK--EKRIAEQDKQ 1888

Query: 1015 NALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDS 1074
               LK++ E +   NQ++++    +M +  + +S+L     +L    E+ +   K + +S
Sbjct: 1889 MEKLKREMENLFGKNQQMDSLASEFMHLKVE-KSELEAKKEELNEAIEQKEIEEKAMQES 1947

Query: 1075 KQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXX 1134
             +H +E  + V++Q+        T L   ++  K E   + ST E       N++     
Sbjct: 1948 MEHLKE-SLKVKQQELDSLHSDVTNLKESLHSLKIENSKLKSTHELQLTKMLNLELKNAE 2006

Query: 1135 XXXXXXXLKVQEEEEFIQERSVLQ-EQSAKLNTELQEC------YTKIIQLETLNTELTG 1187
                    K+++ EE + +  +   E ++K +T L++         K+ +LE L+ +   
Sbjct: 2007 QSK-----KIEKLEESLNKTEISHLEDNSKASTLLKQLEKYKGYMVKVQELEELHQKERE 2061

Query: 1188 HDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQRE 1247
             + +    I+ LK+KL +   + +       + RS++   +     E     + +  + E
Sbjct: 2062 LNKMLSGDIDVLKAKLSKHREKTEEKEQQWKQERSTLQQKITNEIKENEIKLRDYRIEYE 2121

Query: 1248 ADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQ 1280
            +  +K + ++ VQ +   S  +   + + SS++
Sbjct: 2122 SKLEKMKEKMMVQSTIVSSTCDGAPEGIASSSE 2154



 Score =  112 bits (270), Expect = 7e-23
 Identities = 209/1102 (18%), Positives = 467/1102 (42%), Gaps = 85/1102 (7%)

Query: 473  EDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSN 532
            + + E A   E+L+QE+    K  +  DL  +L    EQ   +++E D       +++  
Sbjct: 1078 KQIEEAAAGSEKLEQEIKQMNKAQS--DLQAQLIEKLEQFKCVSNERDEMEVKCARLE-- 1133

Query: 533  HKLKLKQMQKTIDNFSKVSDSNKEI-VRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSG 591
              + +K++Q  ++    ++ SN E    L  +L  + +++++LE++K  ++  L    + 
Sbjct: 1134 --VDMKELQADLEEQKHMTTSNCEAKAALEAQLLAVREELSQLEQDKSRVEETLEKNRAT 1191

Query: 592  RMIESDVYKKMIEMENLAETRLK----AISLLESQKFDLVQELHILQQKYDEVEDKLADI 647
                ++   ++   + L   +++     ++ +   K  + Q+L   Q+K DE+  +L D+
Sbjct: 1192 LEERTETISRLSREKELLSEKVQELATVLATVRQTKSTIQQKLEEQQEKSDELSCQLEDL 1251

Query: 648  SQLQSDQVCSEIKSVHLEEQIDAL--SASKKELALVIENLKLDKEQLYGTIKDLENDKED 705
            +  +   V  E+  V  E++   +  +A K+EL   +E L    E +    +D +  +E+
Sbjct: 1252 NS-KLLAVAEELGRVTEEKEAILIRQNAEKQELVEKVEELT---ESIAMAEEDRDTLREE 1307

Query: 706  IMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIE 765
               +LQ  ++        L++   + + +L  +       K + +  I A  +ERD   E
Sbjct: 1308 KC-RLQAEVERIEHDKGSLDEQCGKLLKQLSKEREDAANEKARQEITIAALGEERDALQE 1366

Query: 766  N---IESELSKYKSRICRLEESIAVME---DRRYSLERKADQLGSYLQE----KQKAYSE 815
                I+ E      ++  LEE+   +E     + ++E K  +L   + E    K K   E
Sbjct: 1367 KLAAIDEERGALAGKVAELEETKTGLECALSDKGAVESKVVELSKLIDELRSEKMKLEGE 1426

Query: 816  YTIQEDELVNR---LAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDM 872
            ++   +EL +    +  L ++ R +E+    ++ +     + N+ L +E Q+L  +L   
Sbjct: 1427 WSSLSEELHSNNKTIEELKENVRTLEESKKNLQSQVSNGNETNKQLRQEVQDLSKALQAS 1486

Query: 873  QQHYNAL-VE-KANRTDLAESEST---------KYQTQLRDLESNLKRITHEHQTLIVQK 921
            +Q   A+ VE K   T+L +SE+          +  +QL+++E+ LK  T E ++ +V +
Sbjct: 1487 KQEIEAMEVETKKLATELTQSEAKVEELSAEIKQTSSQLQEVEAILK--TKERESAVVSE 1544

Query: 922  K--KEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVE 979
            K  +  +DLE+  + + +  ++  + +     +  E   +L+  L E  N    +     
Sbjct: 1545 KLVERTKDLELVRSQKEDVILQQSRNIESIQTEQQELAKRLQQVLTESSNREAEVKQLTG 1604

Query: 980  ELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSY 1039
            ELN  +LEL      K + Q     EQ I    +L    + K  E+     ++N A+ S 
Sbjct: 1605 ELNSRSLEL------KAKEQEVHAKEQEIRSATELLTASEAKAAELSLNVDQLNAAKSSL 1658

Query: 1040 MSMVS------DYESKLAQFT-TKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQI 1092
               +       D+E +L Q T  K E++   +   S+  +  +    +L+I     +   
Sbjct: 1659 EMQIRKLQDDFDHERELCQATERKAEDLAASLSEASESKIRLEHQLHQLEIERTNAESAN 1718

Query: 1093 KELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXL--KVQEEEEF 1150
            ++L +     +  + K +     ++I+    + +++             L  KV + E  
Sbjct: 1719 QQLIQQLSDLKAQVAKQQ-----TSIDAKDTEIHHLTEGLEKVKRIQSHLEEKVTDFESV 1773

Query: 1151 IQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTEN 1210
            + E+  ++ Q  +L  EL+       ++E   TEL   D V +E+ +  +  ++QL  +N
Sbjct: 1774 VTEKDEIETQLIRLQNELETIQDDKRRIE---TEL---DAVKEEKADVDRRLIQQL--QN 1825

Query: 1211 DNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQ 1270
             + ++         +  +  +   + +  ++  A+  A    T    + QL+A E +  +
Sbjct: 1826 YDTVNEAYRNEREANKELQAKQQNLNKKLQEATAE-NALLVHTHESSKAQLAAKEKRIAE 1884

Query: 1271 LLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDE 1330
                ++   +E  N     +Q+ SL ++    +     L+ K  ++   IE  + EIE++
Sbjct: 1885 QDKQMEKLKREMENLFGKNQQMDSLASEFMHLKVEKSELEAKKEELNEAIE--QKEIEEK 1942

Query: 1331 KVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXX 1390
              A                 +L + +     ++E S+ ++  EN++LK +          
Sbjct: 1943 --AMQESMEHLKESLKVKQQELDSLHSDVTNLKE-SLHSLKIENSKLKSTHELQLTKMLN 1999

Query: 1391 XXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVR---QQLVEYEKR 1447
               +  +   K+ +L   L  K    + + +    TL ++ ++++      Q+L E  ++
Sbjct: 2000 LELKNAEQSKKIEKLEESLN-KTEISHLEDNSKASTLLKQLEKYKGYMVKVQELEELHQK 2058

Query: 1448 IEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITES-VSLNKQVA 1506
              +L      ++ +L+ K+ ++    E  +++ + ER  L +++  +I E+ + L     
Sbjct: 2059 ERELNKMLSGDIDVLKAKLSKHREKTEEKEQQWKQERSTLQQKITNEIKENEIKLRDYRI 2118

Query: 1507 ELNKALEEEVAKTNEMQTALEN 1528
            E    LE+   K     T + +
Sbjct: 2119 EYESKLEKMKEKMMVQSTIVSS 2140



 Score =  103 bits (246), Expect = 5e-20
 Identities = 175/947 (18%), Positives = 397/947 (41%), Gaps = 66/947 (6%)

Query: 91   SESLANTLKQKEILMEKIKQYKEL--SKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLS 148
            +E+++   ++KE+L EK+++   +  + R + + ++               QL D+   S
Sbjct: 1196 TETISRLSREKELLSEKVQELATVLATVRQTKSTIQQKLEEQQEKSDELSCQLEDLN--S 1253

Query: 149  NTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXX 208
              +   +    V + K  I+     + QE + + +++ E+   A                
Sbjct: 1254 KLLAVAEELGRVTEEKEAILIRQNAEKQELVEKVEELTESIAMA-EEDRDTLREEKCRLQ 1312

Query: 209  XXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEIS 268
               E  +     + E    +  +   E++    +   +++ I++L E    L+     I 
Sbjct: 1313 AEVERIEHDKGSLDEQCGKLLKQLSKEREDAANEKARQEITIAALGEERDALQEKLAAID 1372

Query: 269  LEHSKLA---QELEQXXXXXXXXXXXXXXLAKQSIEPS------CEEKTEIEEKGSLEIA 319
             E   LA    ELE+              +  + +E S        EK ++E + S    
Sbjct: 1373 EERGALAGKVAELEETKTGLECALSDKGAVESKVVELSKLIDELRSEKMKLEGEWSSLSE 1432

Query: 320  NMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTA 379
             +    K IE L+     + ++ K L+++++     +K +    +  S  +  ++ +   
Sbjct: 1433 ELHSNNKTIEELKENVRTLEESKKNLQSQVSNGNETNKQLRQEVQDLSKAL--QASKQEI 1490

Query: 380  SKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKE---YVISEK--DTX 434
              M+    +L++E    +   +    EI +    +Q +   L  KE    V+SEK  +  
Sbjct: 1491 EAMEVETKKLATELTQSEAKVEELSAEIKQTSSQLQEVEAILKTKERESAVVSEKLVERT 1550

Query: 435  XXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIH--VGTNTEDVNEIAKVQEQLKQELND- 491
                      +D ++ Q +       E   L        TE  N  A+V +QL  ELN  
Sbjct: 1551 KDLELVRSQKEDVILQQSRNIESIQTEQQELAKRLQQVLTESSNREAEV-KQLTGELNSR 1609

Query: 492  ----EIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNF 547
                + K+  V    ++++SA E +T    +    + N+ ++ +       Q++K  D+F
Sbjct: 1610 SLELKAKEQEVHAKEQEIRSATELLTASEAKAAELSLNVDQLNAAKSSLEMQIRKLQDDF 1669

Query: 548  SKVSDSNKEIVRLTE-ELHHLSQKVAELEEEKGNL--QLHLVDYD--SGRMIESDVYKKM 602
                D  +E+ + TE +   L+  ++E  E K  L  QLH ++ +  +       + +++
Sbjct: 1670 ----DHERELCQATERKAEDLAASLSEASESKIRLEHQLHQLEIERTNAESANQQLIQQL 1725

Query: 603  IEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSV 662
             +++     +  +I   +++   L + L  +++    +E+K+ D   + +++   E + +
Sbjct: 1726 SDLKAQVAKQQTSIDAKDTEIHHLTEGLEKVKRIQSHLEEKVTDFESVVTEKDEIETQLI 1785

Query: 663  HLEEQIDALSASKKELALVIENLKLDKEQL-YGTIKDLENDKEDIMNKLQNYIQENMDLT 721
             L+ +++ +   K+ +   ++ +K +K  +    I+ L+N  + +    +N  + N +L 
Sbjct: 1786 RLQNELETIQDDKRRIETELDAVKEEKADVDRRLIQQLQN-YDTVNEAYRNEREANKELQ 1844

Query: 722  DK---LEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKY---K 775
             K   L K   E  +E    ++  E SK Q     + +I E+D  +E ++ E+       
Sbjct: 1845 AKQQNLNKKLQEATAENALLVHTHESSKAQLA-AKEKRIAEQDKQMEKLKREMENLFGKN 1903

Query: 776  SRICRLEESIAVMEDRRYSLERKADQLGSYLQEK---QKAYSEYT--IQEDELVNRLAVL 830
             ++  L      ++  +  LE K ++L   +++K   +KA  E    ++E   V +  + 
Sbjct: 1904 QQMDSLASEFMHLKVEKSELEAKKEELNEAIEQKEIEEKAMQESMEHLKESLKVKQQELD 1963

Query: 831  MDHDRV--VEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDL 888
              H  V  +++ L  ++ EN +L+  +++ L +  NL++  ++  +    L E  N+T++
Sbjct: 1964 SLHSDVTNLKESLHSLKIENSKLKSTHELQLTKMLNLELKNAEQSKKIEKLEESLNKTEI 2023

Query: 889  AESE-STKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLN 947
            +  E ++K  T L+ LE       ++   + VQ+ +E+   E E N  +     D  VL 
Sbjct: 2024 SHLEDNSKASTLLKQLEK------YKGYMVKVQELEELHQKERELNKMLSG---DIDVLK 2074

Query: 948  EKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQ 994
             K  K+ E   + E Q ++ ++ ++    N  E+ +  ++L D  ++
Sbjct: 2075 AKLSKHREKTEEKEQQWKQERSTLQQKITN--EIKENEIKLRDYRIE 2119



 Score = 79.0 bits (186), Expect = 1e-12
 Identities = 181/993 (18%), Positives = 413/993 (41%), Gaps = 68/993 (6%)

Query: 622  QKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALV 681
            Q    V++++I +  Y+ + ++L    +  S ++  E KS  LE+ + AL         V
Sbjct: 477  QDVGFVEKMNIFKSCYESLFEELGKFKE--SKEMLEE-KSDALEKDVRALKTELLARTEV 533

Query: 682  IENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQE-NMDLTDKLEKMS-AEKISELLAKI 739
            +ENL+     +   ++ ++    +   K Q   ++ N    D L+ +S  + +S+    +
Sbjct: 534  LENLERHSADIERQLELVKQTANEYQRKNQALDEDVNRQKRDLLKLISEKDALSQQNLTL 593

Query: 740  NHEEQSKIQTQFGIDAKIQERDLYI-ENIE-SELSKYKSRICRLEESIAVM-EDRR---- 792
            N E  S       + AKI    L + E+ E S+ S +  ++  L+E +  + ED+     
Sbjct: 594  NVEFNSLKGEHESLTAKIDYLMLSLNEDYEGSDFSSWFDKMDDLKERVRTLKEDKERLTG 653

Query: 793  YSLERKADQLG-----SYLQEKQKAYSEYTIQEDELVNRLA-VLMDHDRVVEKQ---LLE 843
             +++   +++G     S  + + K   E   + ++ + RL+  L + ++ +E++   +  
Sbjct: 654  MNMKITMEKVGLEKHISVSEMRLKEMKELHAESEKKLRRLSEQLSESEKALEEKGNCVTS 713

Query: 844  IEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVE--KANRTDL--AESESTKYQTQ 899
            +E    +L++  Q L  E    Q  L++M + + +  E  ++ R +L   + E +  +  
Sbjct: 714  LEKLKADLEENIQGLSAELLESQSKLNEMSEDFQSCEETLRSVRDELESRDQELSCAKNT 773

Query: 900  LRDLESNLKRITHEHQTLI-VQKKKEIEDLEIEFN-TQIESAIRDKKVLNEKYEKNIEYV 957
            + +L++NL++   E Q+ + +Q++   E  ++  N T ++  + ++  + ++  K +E V
Sbjct: 774  IEELQTNLEKQQVELQSAMQLQQETASEKEQLAVNLTDVQQKLSEESEILQETIKKLEQV 833

Query: 958  TQLEAQLQEYKNNIENLNMNVEE-LNKMNLEL--IDKHVQKQQTQSPDYTEQYINEINKL 1014
                 +L E+++N++   + +EE L +   EL    K +Q  + Q  +  +   NE ++ 
Sbjct: 834  NLEWQKLTEHRDNLQQDKLILEEALAEQCNELGKNSKTIQNLELQLQNLQQLLANEADQS 893

Query: 1015 NALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEE-EMQRVSKQLLD 1073
                +  + +II    +++ ++     + +   S L         + + E Q VSK    
Sbjct: 894  KETQQSLNAQIINQQHQLDASRKEQHILSAANRSLLTGLELVQGKITQLEGQYVSKIGTL 953

Query: 1074 SKQHNEELQILVREQDDQIKELKETKLTFEMNIPK--TEGMIISSTIEPMSDDANNVDXX 1131
              +  E   +L +    Q K L+  K   E N+ K   E  I+ +  + + +  N +   
Sbjct: 954  EAKLGEFAALLTKLSAYQFK-LRLEKAQLEDNLGKMIREFEILQTENDKLLEVENALQQT 1012

Query: 1132 XXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLN-TELQECYTKIIQLETLNTELTG--- 1187
                        V+E    ++E+    E    LN   ++E      +LE   T L G   
Sbjct: 1013 VQELRLEKTA--VEERSVGLEEQLAEMEVRVDLNGNRIKELEGSCAELEAERTRLLGDGS 1070

Query: 1188 -HDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQR 1246
              +   Q+QI +  +  E+L  E   +    ++L++ +   ++Q  F+     +  +  +
Sbjct: 1071 QREKELQKQIEEAAAGSEKLEQEIKQMNKAQSDLQAQLIEKLEQ--FKCVSNERDEMEVK 1128

Query: 1247 EADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHL 1306
             A  +    EL+  L   E +      + ++    E   +   E+++ L+   QDK    
Sbjct: 1129 CARLEVDMKELQADL---EEQKHMTTSNCEAKAALEAQLLAVREELSQLE---QDKSRVE 1182

Query: 1307 RNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQS 1366
              L++  A +  + E + S +  EK                      T  Q  ++ QE+S
Sbjct: 1183 ETLEKNRATLEERTETI-SRLSREKELLSEKVQELATVLATVRQTKSTIQQKLEEQQEKS 1241

Query: 1367 ILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTIT 1426
                +E + QL+  +               + EA ++    +   +  E+ +K  E T +
Sbjct: 1242 ----DELSCQLEDLNSKLLAVAEELGRVTEEKEAILI----RQNAEKQELVEKVEELTES 1293

Query: 1427 LTQRNDEFENVRQQLVEYEKRIEDLTYEK---ESELAILRLKMHENANHYETMQKESEIE 1483
            +    ++ + +R++    +  +E + ++K   + +   L  ++ +        +   EI 
Sbjct: 1294 IAMAEEDRDTLREEKCRLQAEVERIEHDKGSLDEQCGKLLKQLSKEREDAANEKARQEIT 1353

Query: 1484 RVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNL 1543
               L EE +  + E ++    + E   AL  +VA+  E +T LE    +   +  ++  L
Sbjct: 1354 IAALGEERDA-LQEKLA---AIDEERGALAGKVAELEETKTGLECALSDKGAVESKVVEL 1409

Query: 1544 QNMV---RASSSKIQKHVSFASDTKQGRDEQLD 1573
              ++   R+   K++   S  S+     ++ ++
Sbjct: 1410 SKLIDELRSEKMKLEGEWSSLSEELHSNNKTIE 1442



 Score = 65.3 bits (152), Expect = 1e-08
 Identities = 138/741 (18%), Positives = 283/741 (38%), Gaps = 36/741 (4%)

Query: 863  QNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKK 922
            + + I  S  +  +  L +     ++ E +S   +  +R L++ L   T   + L     
Sbjct: 483  EKMNIFKSCYESLFEELGKFKESKEMLEEKSDALEKDVRALKTELLARTEVLENLERHSA 542

Query: 923  KEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELN 982
                 LE+   T  E   R  + L+E   +    + +L ++          LN+    L 
Sbjct: 543  DIERQLELVKQTANEYQ-RKNQALDEDVNRQKRDLLKLISEKDALSQQNLTLNVEFNSLK 601

Query: 983  KMNLELIDKHVQKQQTQSPDYT-EQYINEINKLNAL------LKQKDEEIIALNQKINNA 1035
              +  L  K      + + DY    + +  +K++ L      LK+  E +  +N KI   
Sbjct: 602  GEHESLTAKIDYLMLSLNEDYEGSDFSSWFDKMDDLKERVRTLKEDKERLTGMNMKITME 661

Query: 1036 QVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEE-------LQILVREQ 1088
            +V     +S  E +L +        E++++R+S+QL +S++  EE       L+ L  + 
Sbjct: 662  KVGLEKHISVSEMRLKEMKELHAESEKKLRRLSEQLSESEKALEEKGNCVTSLEKLKADL 721

Query: 1089 DDQIKELKETKLTFE--MNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQE 1146
            ++ I+ L    L  +  +N    +      T+  + D+  + D            L+   
Sbjct: 722  EENIQGLSAELLESQSKLNEMSEDFQSCEETLRSVRDELESRDQELSCAKNTIEELQTNL 781

Query: 1147 EEEFIQERSV--LQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLE 1204
            E++ ++ +S   LQ+++A    +L    T + Q  +  +E+    +   EQ+N    KL 
Sbjct: 782  EKQQVELQSAMQLQQETASEKEQLAVNLTDVQQKLSEESEILQETIKKLEQVNLEWQKLT 841

Query: 1205 QL--NTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLS 1262
            +   N + D L+   A          + +  +  EL  Q+L Q  A+      E +  L+
Sbjct: 842  EHRDNLQQDKLILEEALAEQCNELGKNSKTIQNLELQLQNLQQLLANEADQSKETQQSLN 901

Query: 1263 AFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEI 1322
            A     +  LD+  S  ++          +T L+  +Q K   +  L+ +Y   I  +E 
Sbjct: 902  AQIINQQHQLDA--SRKEQHILSAANRSLLTGLE-LVQGK---ITQLEGQYVSKIGTLEA 955

Query: 1323 LRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSX 1382
               E                        +L    + ++ +Q ++   +  ENA L+++  
Sbjct: 956  KLGEFAALLTKLSAYQFKLRLEKAQLEDNLGKMIREFEILQTENDKLLEVENA-LQQTVQ 1014

Query: 1383 XXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLV 1442
                       R    E ++ E+  +++L  + I +          +R     +  Q+  
Sbjct: 1015 ELRLEKTAVEERSVGLEEQLAEMEVRVDLNGNRIKELEGSCAELEAERTRLLGDGSQREK 1074

Query: 1443 EYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLI-EELNVKITESVSL 1501
            E +K+IE+      SE     +K    A      Q   ++E+ K +  E +    +   L
Sbjct: 1075 ELQKQIEEAA--AGSEKLEQEIKQMNKAQSDLQAQLIEKLEQFKCVSNERDEMEVKCARL 1132

Query: 1502 NKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFA 1561
               + EL   LEE+   T     A    E +++ + +E++ L+       S++++ +   
Sbjct: 1133 EVDMKELQADLEEQKHMTTSNCEAKAALEAQLLAVREELSQLEQ----DKSRVEETLEKN 1188

Query: 1562 SDTKQGRDEQLDN-TMNKELL 1581
              T + R E +   +  KELL
Sbjct: 1189 RATLEERTETISRLSREKELL 1209



 Score = 54.4 bits (125), Expect = 2e-05
 Identities = 140/737 (18%), Positives = 300/737 (40%), Gaps = 59/737 (8%)

Query: 838  EKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQ 897
            EK  LE++   K+LQ KN+  LE+ +     + +++    A     NR    E+ES   Q
Sbjct: 231  EKGYLEVQL--KQLQDKNEKFLEDKRKYVKEIRELRTELQA----CNR----ENESPNKQ 280

Query: 898  TQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYV 957
               R  +  + RI    + L+ +K++ ++ L IE  T  E+     +++N    +N++ +
Sbjct: 281  ---RGADHKVARI----ERLLAEKEEALDRLRIELETVAENNRNSTEMIN---YRNVQ-I 329

Query: 958  TQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNAL 1017
             +L+ Q+QE +N++ +L+  + E +++   L + + + Q+       +Q I     LN  
Sbjct: 330  VKLKDQIQELENSLGSLSECIAEKDEVIKCLRENNEELQRFIEESRFKQNIPLPENLNTS 389

Query: 1018 LKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQH 1077
                 E     +   N    SY     +    +     K +  E  + + S ++++ ++ 
Sbjct: 390  FDGMMELSSGGSSNGNGTGRSYNITPENMAHAVVDVQLKEKEAENCLLKRSLEIIEQEKV 449

Query: 1078 NEE--LQILVREQDDQIKELKETKLTFEMNIPKTEGM-IISSTIEPMSDDANNVDXXXXX 1134
                 +    R   D +  +         ++   E M I  S  E + ++          
Sbjct: 450  RVSGLVGSFFRLYGDLVGAMPYGSAN-PQDVGFVEKMNIFKSCYESLFEELGKFKESKEM 508

Query: 1135 XXXXXXXLK--VQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVN 1192
                   L+  V+  +  +  R+ + E   + + +++       QLE +      +   N
Sbjct: 509  LEEKSDALEKDVRALKTELLARTEVLENLERHSADIER------QLELVKQTANEYQRKN 562

Query: 1193 Q---EQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREAD 1249
            Q   E +N+ K  L +L +E D L      L    +S   +     A++    L+  E D
Sbjct: 563  QALDEDVNRQKRDLLKLISEKDALSQQNLTLNVEFNSLKGEHESLTAKIDYLMLSLNE-D 621

Query: 1250 FQKTEHELRVQLSAFESKYEQLLDSVQSSTQEE-----TNKIVTMEQVTSLQNKLQDKEE 1304
            ++ ++       S++  K + L + V++  +++      N  +TME+V  L+  +   E 
Sbjct: 622  YEGSD------FSSWFDKMDDLKERVRTLKEDKERLTGMNMKITMEKV-GLEKHISVSEM 674

Query: 1305 HLRNLQEKYADVINQIEILRSEI-EDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQ 1363
             L+ ++E +A+   ++  L  ++ E EK                   +   +  S + ++
Sbjct: 675  RLKEMKELHAESEKKLRRLSEQLSESEKALEEKGNCVTSLEKLKADLEENIQGLSAELLE 734

Query: 1364 EQSILN-INEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHE 1422
             QS LN ++E+    +++              ++ A+  + EL   LE +  E+      
Sbjct: 735  SQSKLNEMSEDFQSCEETLRSVRDELESRDQELSCAKNTIEELQTNLEKQQVELQSAMQL 794

Query: 1423 YTITLTQRNDEFENVR--QQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKES 1480
               T +++     N+   QQ +  E  I   T +K   L  + L+  +   H + +Q++ 
Sbjct: 795  QQETASEKEQLAVNLTDVQQKLSEESEILQETIKK---LEQVNLEWQKLTEHRDNLQQDK 851

Query: 1481 EIERVKLIEELNV--KITESV-SLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLN 1537
             I    L E+ N   K ++++ +L  Q+  L + L  E  ++ E Q +L  Q I      
Sbjct: 852  LILEEALAEQCNELGKNSKTIQNLELQLQNLQQLLANEADQSKETQQSLNAQIINQQHQL 911

Query: 1538 DEITNLQNMVRASSSKI 1554
            D     Q+++ A++  +
Sbjct: 912  DASRKEQHILSAANRSL 928


>UniRef50_A0BIX7 Cluster: Chromosome undetermined scaffold_11, whole
            genome shotgun sequence; n=2; Paramecium tetraurelia|Rep:
            Chromosome undetermined scaffold_11, whole genome shotgun
            sequence - Paramecium tetraurelia
          Length = 1014

 Score =  128 bits (308), Expect = 2e-27
 Identities = 198/976 (20%), Positives = 437/976 (44%), Gaps = 80/976 (8%)

Query: 395  NQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQL 454
            NQ  + +   +EI++L++ +   + ++   +  ++  D            K+T  +++ L
Sbjct: 3    NQSPEPEKQSDEISRLKLSLMMKDNEIRALKLKVNPSDEIERLQQEAEKMKETYESEINL 62

Query: 455  EHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQ 514
              +++ E   L+     T+D  E  K     K +   E+K  N  D I K +S   ++ Q
Sbjct: 63   LKEENYEYSELLK---ETQDQAEFLKSVVIGKDKEIAELKSQNANDEIVKSRSRNGEL-Q 118

Query: 515  LNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAEL 574
            L    +A  KN +++    KL    + K + +    S      V     L+  +Q ++ L
Sbjct: 119  LALAENANLKNELQILQT-KLDDAYLSKQVMDEQLQSLGQMLEVEQRNTLNQANQ-ISTL 176

Query: 575  EEEKGNLQLHLVDYDSGRMIESDVYK-KMIEMENLAETRLKAISLLESQKFDLVQELHIL 633
            ++E   L+  + D +   + +  + K K  E+    E     ++ L   + D    +   
Sbjct: 177  QKEAQYLRNSVNDRERFIVGKEKIIKLKDGEINRQQEIINDTLAKLAEMQHDNQVIVTQN 236

Query: 634  QQKYDEVEDKLADISQLQSDQV---CSEIKSV-HLEEQIDALSASKKELALVIENLKLDK 689
             Q Y  +++K A+I  L+ DQ+     +++ V + E Q +   A  K+LA  I+ L+   
Sbjct: 237  DQYYKLLQEKQAEIDSLK-DQLQFFAEDLQRVQNYEGQYNDAQAKIKQLAQYIQELE--- 292

Query: 690  EQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQT 749
            +QL   +   E   ++++N  +    E     D+LEK ++ K ++L A+  +++ S++Q 
Sbjct: 293  KQLQDQMNQYEKQIKELLNNAKATEDEKDHNIDQLEKDNSNKANQLEAQ--NKQISQLQK 350

Query: 750  QFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEK 809
            +   DA   +RD  +++++ +L     +   L+++   ++D+    + +A Q+ +  +E 
Sbjct: 351  ELK-DAD-NKRDREVKDVQRKLDAELKKTATLDKNNKTLKDKN---DEQAKQINAANEEL 405

Query: 810  QKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISL 869
                       D+L  ++A L    +  + Q+ ++E E K+L K+ Q L+++N NL    
Sbjct: 406  -----------DQLDQKIADLEQKVKDQQNQIKDLEKEIKDLNKEKQNLIQDNNNLH--- 451

Query: 870  SDMQQHYNALVEKA--NRTDL--AESESTKYQTQLRDLESNLKRITHEHQTL---IVQKK 922
                Q +N   EKA   + DL  A+ E          L  +L     E++ L   I    
Sbjct: 452  ----QKFNQAEEKALQQQKDLVKAQKELNDKHNNAEQLNKDLDEYEQENKELQKEINSLN 507

Query: 923  KEIEDLEIEFN---TQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVE 979
             +I  L  E N    QI+   +D + L E  EK  +     + + ++ + N  +LN  + 
Sbjct: 508  DQINQLNKEINQKQKQIDQQAKDIQKLQENLEKQKQDNQSKQQENKQLQQNNNDLNKQLN 567

Query: 980  ELNKMNLELIDK--HVQKQQTQSPDYTEQYI----NEINKLNALLKQKDEEIIALNQKIN 1033
            E  K N +L D+  + +++Q ++ D  +  +    NEI +L   +K++++E   L  ++N
Sbjct: 568  ESKKQNQKLQDQINNTEQKQNKTQDQLKNQLQDAQNEIKQLKDQIKEQEKEKKNLQNEVN 627

Query: 1034 NAQVSYMSMVSDYESKL--AQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQ 1091
            N       + +  + K+   Q  +++  + +E+ +  +QL   KQ  ++L   V+ + ++
Sbjct: 628  NLNKECDDLDAKLQQKIKEQQENSEINRLNDELNKAQQQL---KQKEDQL-TKVQNELNK 683

Query: 1092 IKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLK--VQEEEE 1149
            +KE K+ K   E      +   +   ++ +  + +++D            LK  +Q   +
Sbjct: 684  LKEQKQ-KEQKEQKDKDQQRKDLEKQVKDLDAECDHLDQQRQAAINEAEKLKQELQNLND 742

Query: 1150 FIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVV---NQ--EQINQLKSKLE 1204
              ++    Q + A+   ++ +   + ++ +    E    + +   NQ  + +++  S+L+
Sbjct: 743  LKKQLKDTQNKLAQAEKQIAQLDPEAVKNKLQKAEQDAKNAIQAQNQAKKDLDKANSQLK 802

Query: 1205 QLNTENDNLLSTVAELRSSISSAVD---QRGFEIAELWKQ--HLAQREADFQKTEHELRV 1259
            Q   EN +L      L + + +  +   Q+  EI E  KQ   L +     +K + +  +
Sbjct: 803  QKEKENKDLDDECNALDTQVQNLKEQAKQQEDEIKEKQKQIDQLQKENQQLKKDDIKGEI 862

Query: 1260 -QLSAFESKYEQLLDSVQ-SSTQEETNKIVTMEQVTSLQ---NKLQDKEEHLRNLQEKYA 1314
             +L  F  + + +LD+++  STQ +  +    +Q+   Q   NKL+ K+    +  ++  
Sbjct: 863  DKLRKFIQEQKPILDNLEKESTQSDKRRSDLEKQIAKSQDDLNKLKKKKGGNGDDDQQIQ 922

Query: 1315 DVINQIEILRSEIEDE 1330
             ++ +++ L ++++ E
Sbjct: 923  GLVQKLDELDNKLQQE 938



 Score =  126 bits (304), Expect = 5e-27
 Identities = 184/853 (21%), Positives = 388/853 (45%), Gaps = 78/853 (9%)

Query: 527  IKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLV 586
            +K+K N   +++++Q+  +   +  +S  EI  L EE +  S+ + E +++   L+  ++
Sbjct: 32   LKLKVNPSDEIERLQQEAEKMKETYES--EINLLKEENYEYSELLKETQDQAEFLKSVVI 89

Query: 587  DYDSGRMIESDVYKKMIEMENLAETRLK--AISLLESQKFDLVQELHILQQKYDEVE-DK 643
              D     E    K     + + ++R +   + L  ++  +L  EL ILQ K D+    K
Sbjct: 90   GKDK----EIAELKSQNANDEIVKSRSRNGELQLALAENANLKNELQILQTKLDDAYLSK 145

Query: 644  LADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQ-LYGT-----IK 697
                 QLQS     E++  +   Q + +S  +KE A  + N   D+E+ + G      +K
Sbjct: 146  QVMDEQLQSLGQMLEVEQRNTLNQANQISTLQKE-AQYLRNSVNDRERFIVGKEKIIKLK 204

Query: 698  DLE-NDKEDIMN----KLQNYIQENMDLT---DKLEKMSAEKISELLAKINH-----EEQ 744
            D E N +++I+N    KL     +N  +    D+  K+  EK +E+ +  +      E+ 
Sbjct: 205  DGEINRQQEIINDTLAKLAEMQHDNQVIVTQNDQYYKLLQEKQAEIDSLKDQLQFFAEDL 264

Query: 745  SKIQTQFG----IDAKIQERDLYIENIESEL----SKYKSRICRLEESIAVMEDRRYSLE 796
             ++Q   G      AKI++   YI+ +E +L    ++Y+ +I  L  +    ED +   +
Sbjct: 265  QRVQNYEGQYNDAQAKIKQLAQYIQELEKQLQDQMNQYEKQIKELLNNAKATEDEK---D 321

Query: 797  RKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQ 856
               DQL        KA ++   Q  ++      L D D   ++++ +++ +     KK  
Sbjct: 322  HNIDQLEK--DNSNKA-NQLEAQNKQISQLQKELKDADNKRDREVKDVQRKLDAELKKTA 378

Query: 857  ILLEENQNLQISLSDMQQHYNALVEKANRTD--LAESEST--KYQTQLRDLESNLKRITH 912
             L + N+ L+    +  +  NA  E+ ++ D  +A+ E      Q Q++DLE  +K +  
Sbjct: 379  TLDKNNKTLKDKNDEQAKQINAANEELDQLDQKIADLEQKVKDQQNQIKDLEKEIKDLNK 438

Query: 913  EHQTLIVQKK---KEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKN 969
            E Q LI       ++    E +   Q +  ++ +K LN+K+    +    L+   QE K 
Sbjct: 439  EKQNLIQDNNNLHQKFNQAEEKALQQQKDLVKAQKELNDKHNNAEQLNKDLDEYEQENKE 498

Query: 970  NIENLNMNVEELNKMNLELIDKHVQ-KQQTQSPDYTEQYINEINKLNALLKQKDEEIIA- 1027
              + +N   +++N++N E+  K  Q  QQ +     ++ + +  + N   +Q+++++   
Sbjct: 499  LQKEINSLNDQINQLNKEINQKQKQIDQQAKDIQKLQENLEKQKQDNQSKQQENKQLQQN 558

Query: 1028 ---LNQKINNAQVSYMSM---VSDYESKLAQFTTKLENMEEEMQRVSKQLLDS-KQHNEE 1080
               LN+++N ++     +   +++ E K  +   +L+N  ++ Q   KQL D  K+  +E
Sbjct: 559  NNDLNKQLNESKKQNQKLQDQINNTEQKQNKTQDQLKNQLQDAQNEIKQLKDQIKEQEKE 618

Query: 1081 LQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXX 1140
             + L  E ++  KE  +     +  I + +    +S I  ++D+ N              
Sbjct: 619  KKNLQNEVNNLNKECDDLDAKLQQKIKEQQE---NSEINRLNDELNKAQQQLKQKEDQLT 675

Query: 1141 XLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLK 1200
              KVQ E   ++E+   +++  K   + ++   K  Q++ L+ E    D   Q  IN+ +
Sbjct: 676  --KVQNELNKLKEQKQKEQKEQKDKDQQRKDLEK--QVKDLDAECDHLDQQRQAAINEAE 731

Query: 1201 SKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQ 1260
               ++L   ND L   + + ++ ++ A  Q    IA+L  + +  +    QK E + +  
Sbjct: 732  KLKQELQNLND-LKKQLKDTQNKLAQAEKQ----IAQLDPEAVKNK---LQKAEQDAKNA 783

Query: 1261 LSAFESKYEQLLDSVQSSTQ--EETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVIN 1318
            + A +++ ++ LD   S  +  E+ NK +  ++  +L  ++Q+ +E  +  +++  +   
Sbjct: 784  IQA-QNQAKKDLDKANSQLKQKEKENKDLD-DECNALDTQVQNLKEQAKQQEDEIKEKQK 841

Query: 1319 QIEILRSEIEDEK 1331
            QI+ L+ E +  K
Sbjct: 842  QIDQLQKENQQLK 854



 Score =  115 bits (277), Expect = 9e-24
 Identities = 179/955 (18%), Positives = 408/955 (42%), Gaps = 57/955 (5%)

Query: 101  KEILMEKIKQYKEL-SKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNALS 159
            K +++ K K+  EL S+ ++  IV+                L +  +L N ++     L 
Sbjct: 85   KSVVIGKDKEIAELKSQNANDEIVKSRSRNGELQLA-----LAENANLKNELQILQTKLD 139

Query: 160  VLQVKMKIMETTILDLQE--KINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQ 217
               +  ++M+  +  L +  ++ +++ + +A   +T                     K++
Sbjct: 140  DAYLSKQVMDEQLQSLGQMLEVEQRNTLNQANQISTLQKEAQYLRNSVNDRERFIVGKEK 199

Query: 218  MTKMQENFIAMEAEWKDEKQRLLKDIE-SKDVRISSLEEANKLLEAARFEISLEHSKL-- 274
            + K+++  I  + E  ++    L +++    V ++  ++  KLL+  + EI     +L  
Sbjct: 200  IIKLKDGEINRQQEIINDTLAKLAEMQHDNQVIVTQNDQYYKLLQEKQAEIDSLKDQLQF 259

Query: 275  -AQELEQXXXXXXXXXXXXXXLAK-----QSIEPSCEEKTEIEEKGSLEIANMTELTKKI 328
             A++L++              + +     Q +E   +++    EK   E+ N  + T+  
Sbjct: 260  FAEDLQRVQNYEGQYNDAQAKIKQLAQYIQELEKQLQDQMNQYEKQIKELLNNAKATEDE 319

Query: 329  ELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQ 388
            +  +H    I Q  K+  NK   +  ++K +S   K+       K  R      +   ++
Sbjct: 320  K--DH---NIDQLEKDNSNKANQLEAQNKQISQLQKELKDA-DNKRDREVKDVQRKLDAE 373

Query: 389  LSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTL 448
            L  +T   D + K  K++  +    I + N++L   +  I++ +             +  
Sbjct: 374  LK-KTATLDKNNKTLKDKNDEQAKQINAANEELDQLDQKIADLEQKVKDQQNQIKDLEKE 432

Query: 449  IAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLK--QELNDEIKDVNV--KDLIE- 503
            I  L  E Q  ++  + +H   N  +   + + ++ +K  +ELND+  +     KDL E 
Sbjct: 433  IKDLNKEKQNLIQDNNNLHQKFNQAEEKALQQQKDLVKAQKELNDKHNNAEQLNKDLDEY 492

Query: 504  --KLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNK----EI 557
              + K  +++I  LND+I+  NK + + +     + K +QK  +N  K    N+    E 
Sbjct: 493  EQENKELQKEINSLNDQINQLNKEINQKQKQIDQQAKDIQKLQENLEKQKQDNQSKQQEN 552

Query: 558  VRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLK-AI 616
             +L +  + L++++ E +++   LQ  + + +  +    D  K  ++       +LK  I
Sbjct: 553  KQLQQNNNDLNKQLNESKKQNQKLQDQINNTEQKQNKTQDQLKNQLQDAQNEIKQLKDQI 612

Query: 617  SLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVH--LEEQIDALSAS 674
               E +K +L  E++ L ++ D+++ KL    +++  Q  SEI  ++  L +    L   
Sbjct: 613  KEQEKEKKNLQNEVNNLNKECDDLDAKLQQ--KIKEQQENSEINRLNDELNKAQQQLKQK 670

Query: 675  KKELALV---IENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQE--NMDLTDKLEKMSA 729
            + +L  V   +  LK  K++     KD +  ++D+  ++++   E  ++D   +     A
Sbjct: 671  EDQLTKVQNELNKLKEQKQKEQKEQKDKDQQRKDLEKQVKDLDAECDHLDQQRQAAINEA 730

Query: 730  EKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVME 789
            EK+ + L  +N  ++    TQ     K+ + +  I  ++ E  K K +    +   A+  
Sbjct: 731  EKLKQELQNLNDLKKQLKDTQ----NKLAQAEKQIAQLDPEAVKNKLQKAEQDAKNAIQA 786

Query: 790  DRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENK 849
              +   ++  D+  S L++K+K   +   + + L  ++  L +  +  E ++ E + +  
Sbjct: 787  QNQ--AKKDLDKANSQLKQKEKENKDLDDECNALDTQVQNLKEQAKQQEDEIKEKQKQID 844

Query: 850  ELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKR 909
            +LQK+NQ L +++   +I   D  + +  + E+    D  E EST+   +  DLE  + +
Sbjct: 845  QLQKENQQLKKDDIKGEI---DKLRKF--IQEQKPILDNLEKESTQSDKRRSDLEKQIAK 899

Query: 910  ITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKN 969
             + +    + +KK    D + +    ++        L ++ +K IE V+ +E  L +   
Sbjct: 900  -SQDDLNKLKKKKGGNGDDDQQIQGLVQKLDELDNKLQQEVDKYIESVSNIEKLLTDITE 958

Query: 970  NIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEE 1024
             +  L + + E+ + + +  +   Q  +    DY +        +  LLKQ +++
Sbjct: 959  KLLKLKLQINEVQEEDGQQFNDVFQLVKNLCNDYKQGLATHNQAMEDLLKQINKQ 1013



 Score =  102 bits (245), Expect = 7e-20
 Identities = 141/645 (21%), Positives = 295/645 (45%), Gaps = 75/645 (11%)

Query: 480  KVQEQLKQ--ELNDEIK--DVNVKDLIEKLKSAEEQITQLNDEIDAANK---NMIKVKSN 532
            K  EQ KQ    N+E+   D  + DL +K+K  + QI  L  EI   NK   N+I+  +N
Sbjct: 390  KNDEQAKQINAANEELDQLDQKIADLEQKVKDQQNQIKDLEKEIKDLNKEKQNLIQDNNN 449

Query: 533  HKLKLKQMQ-KTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDY-DS 590
               K  Q + K +     +  + KE+         L++ + E E+E   LQ  +    D 
Sbjct: 450  LHQKFNQAEEKALQQQKDLVKAQKELNDKHNNAEQLNKDLDEYEQENKELQKEINSLNDQ 509

Query: 591  GRMIESDVYKKMIEMENLAETRLKAISLLESQKFD---LVQELHILQQKYDEVEDKLADI 647
               +  ++ +K  +++  A+   K    LE QK D     QE   LQQ  +++  +L + 
Sbjct: 510  INQLNKEINQKQKQIDQQAKDIQKLQENLEKQKQDNQSKQQENKQLQQNNNDLNKQLNE- 568

Query: 648  SQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIM 707
            S+ Q+ ++  +I +   ++     + ++ +L   +++ + + +QL   IK+ E +K+++ 
Sbjct: 569  SKKQNQKLQDQINNTEQKQ-----NKTQDQLKNQLQDAQNEIKQLKDQIKEQEKEKKNLQ 623

Query: 708  NKLQNYIQENMDLTDKLE-KMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIEN 766
            N++ N  +E  DL  KL+ K+  ++ +  + ++N +E +K Q Q      +++++  +  
Sbjct: 624  NEVNNLNKECDDLDAKLQQKIKEQQENSEINRLN-DELNKAQQQ------LKQKEDQLTK 676

Query: 767  IESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYL----QEKQKAYSEYTIQEDE 822
            +++EL+K K +  + ++     + +R  LE++   L +      Q++Q A +E    + E
Sbjct: 677  VQNELNKLKEQKQKEQKEQKDKDQQRKDLEKQVKDLDAECDHLDQQRQAAINEAEKLKQE 736

Query: 823  LVN------RLAVLMDHDRVVEKQLLEIEHE--NKELQKKNQILLEENQNLQISLSDMQQ 874
            L N      +L    +     EKQ+ +++ E    +LQK  Q      Q    +  D+ +
Sbjct: 737  LQNLNDLKKQLKDTQNKLAQAEKQIAQLDPEAVKNKLQKAEQDAKNAIQAQNQAKKDLDK 796

Query: 875  HYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNT 934
              + L +K       + E     TQ+++L+   K+   E    I +K+K+I+ L+ E N 
Sbjct: 797  ANSQLKQKEKENKDLDDECNALDTQVQNLKEQAKQQEDE----IKEKQKQIDQLQKE-NQ 851

Query: 935  Q-----IESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIEN-LNMNVEELNKMNLEL 988
            Q     I+  I   +   ++ +  ++ + +   Q  + ++++E  +  + ++LNK+  + 
Sbjct: 852  QLKKDDIKGEIDKLRKFIQEQKPILDNLEKESTQSDKRRSDLEKQIAKSQDDLNKLKKKK 911

Query: 989  IDKHVQKQQTQS------------PDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQ 1036
                   QQ Q                 ++YI  ++ +  LL    E+++ L  +IN  Q
Sbjct: 912  GGNGDDDQQIQGLVQKLDELDNKLQQEVDKYIESVSNIEKLLTDITEKLLKLKLQINEVQ 971

Query: 1037 VS-----------YMSMVSDYESKLAQFTTKLENMEEEMQRVSKQ 1070
                           ++ +DY+  LA   T  + ME+ +++++KQ
Sbjct: 972  EEDGQQFNDVFQLVKNLCNDYKQGLA---THNQAMEDLLKQINKQ 1013



 Score = 89.8 bits (213), Expect = 5e-16
 Identities = 195/959 (20%), Positives = 405/959 (42%), Gaps = 114/959 (11%)

Query: 665  EEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKL 724
            E+Q D +S  K  L +    ++  K      +K   +D+ + + +    ++E  +    L
Sbjct: 9    EKQSDEISRLKLSLMMKDNEIRALK------LKVNPSDEIERLQQEAEKMKETYESEINL 62

Query: 725  EKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEES 784
             K    + SELL +   + +       G D +I E  L  +N   E+ K +SR   L+ +
Sbjct: 63   LKEENYEYSELLKETQDQAEFLKSVVIGKDKEIAE--LKSQNANDEIVKSRSRNGELQLA 120

Query: 785  IAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEI 844
            +A       +L+ +   L + L +   AY    + +++L +              Q+LE+
Sbjct: 121  LA----ENANLKNELQILQTKLDD---AYLSKQVMDEQLQSL------------GQMLEV 161

Query: 845  EHENKELQKKNQI--LLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRD 902
            E  N  L + NQI  L +E Q L+ S++D ++    +V K     L + E  + Q  + D
Sbjct: 162  EQRNT-LNQANQISTLQKEAQYLRNSVNDRERF---IVGKEKIIKLKDGEINRQQEIIND 217

Query: 903  LESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEA 962
              + L  + H++Q ++ Q  +  + L+ E   +I+S ++D+    + + ++++ V   E 
Sbjct: 218  TLAKLAEMQHDNQVIVTQNDQYYKLLQ-EKQAEIDS-LKDQL---QFFAEDLQRVQNYEG 272

Query: 963  QLQEYKNNIENLNMNVEELNKM---NLELIDKHVQKQQTQSPDYTEQYINEINKLNALLK 1019
            Q  + +  I+ L   ++EL K     +   +K +++    +    ++  + I++L     
Sbjct: 273  QYNDAQAKIKQLAQYIQELEKQLQDQMNQYEKQIKELLNNAKATEDEKDHNIDQLEKDNS 332

Query: 1020 QKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNE 1079
             K  ++ A N++I+  Q       +  + ++     KL+   ++   + K     K  N+
Sbjct: 333  NKANQLEAQNKQISQLQKELKDADNKRDREVKDVQRKLDAELKKTATLDKNNKTLKDKND 392

Query: 1080 ELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXX 1139
            E    +   ++++ +L +     E  +   +  I    +E    D N             
Sbjct: 393  EQAKQINAANEELDQLDQKIADLEQKVKDQQNQI--KDLEKEIKDLNKEKQNLIQDNNNL 450

Query: 1140 XXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQL 1199
                 Q EE+ +Q++  L +   +LN +           E LN +L  ++  N+E   ++
Sbjct: 451  HQKFNQAEEKALQQQKDLVKAQKELNDKHNNA-------EQLNKDLDEYEQENKELQKEI 503

Query: 1200 KSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRV 1259
             S  +Q+N  N  +        +     +DQ+  +I +L +++L +++ D Q  + E + 
Sbjct: 504  NSLNDQINQLNKEI--------NQKQKQIDQQAKDIQKL-QENLEKQKQDNQSKQQENK- 553

Query: 1260 QLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQ 1319
            QL    +   + L+  +   Q+  ++I   EQ    QNK QD+      L+ +  D  N+
Sbjct: 554  QLQQNNNDLNKQLNESKKQNQKLQDQINNTEQK---QNKTQDQ------LKNQLQDAQNE 604

Query: 1320 IEILRSEI-EDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLK 1378
            I+ L+ +I E EK                   D + + Q  K+ QE S   IN  N +L 
Sbjct: 605  IKQLKDQIKEQEKEKKNLQNEVNNLNKECDDLDAKLQ-QKIKEQQENS--EINRLNDELN 661

Query: 1379 KSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVR 1438
            K+             ++   E ++ ++ ++L  K  E  QK  +          E ++  
Sbjct: 662  KAQQ-----------QLKQKEDQLTKVQNELN-KLKEQKQKEQK----------EQKDKD 699

Query: 1439 QQLVEYEKRIEDLTYE-----KESELAI---LRLKMH-ENANHYETMQKESE---IERVK 1486
            QQ  + EK+++DL  E     ++ + AI    +LK   +N N  +   K+++    +  K
Sbjct: 700  QQRKDLEKQVKDLDAECDHLDQQRQAAINEAEKLKQELQNLNDLKKQLKDTQNKLAQAEK 759

Query: 1487 LIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTA---LENQEIEIVTLNDEITNL 1543
             I +L+ +  ++  L K   +   A++ +     ++  A   L+ +E E   L+DE   L
Sbjct: 760  QIAQLDPEAVKN-KLQKAEQDAKNAIQAQNQAKKDLDKANSQLKQKEKENKDLDDECNAL 818

Query: 1544 QNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELD-LAMYMLHQRDV 1601
               V+    + ++      + KQ + +QL    N++L     + E+D L  ++  Q+ +
Sbjct: 819  DTQVQNLKEQAKQQEDEIKE-KQKQIDQLQKE-NQQLKKDDIKGEIDKLRKFIQEQKPI 875



 Score = 89.4 bits (212), Expect = 7e-16
 Identities = 128/620 (20%), Positives = 267/620 (43%), Gaps = 75/620 (12%)

Query: 999  QSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLE 1058
            QSP+  E+  +EI++L   L  KD EI AL  K+N +      +  + E     + +++ 
Sbjct: 4    QSPE-PEKQSDEISRLKLSLMMKDNEIRALKLKVNPSD-EIERLQQEAEKMKETYESEIN 61

Query: 1059 NMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFE----------MNIPK 1108
             ++EE    S+ L +++   E L+ +V  +D +I ELK      E          + +  
Sbjct: 62   LLKEENYEYSELLKETQDQAEFLKSVVIGKDKEIAELKSQNANDEIVKSRSRNGELQLAL 121

Query: 1109 TEGMIISSTIEPMS---DDAN-NVDXXXXXXXXXXXXLKVQEEEEFIQER--SVLQEQSA 1162
             E   + + ++ +    DDA  +              L+V++     Q    S LQ+++ 
Sbjct: 122  AENANLKNELQILQTKLDDAYLSKQVMDEQLQSLGQMLEVEQRNTLNQANQISTLQKEAQ 181

Query: 1163 KLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLN-------TENDNLLS 1215
             L   + +    I+  E +     G     QE IN   +KL ++        T+ND    
Sbjct: 182  YLRNSVNDRERFIVGKEKIIKLKDGEINRQQEIINDTLAKLAEMQHDNQVIVTQNDQYYK 241

Query: 1216 TVAELRSSISSAVDQRGFEIAELWKQH------------LAQREADFQKTEHELRVQLSA 1263
             + E ++ I S  DQ  F   +L +              + Q     Q+ E +L+ Q++ 
Sbjct: 242  LLQEKQAEIDSLKDQLQFFAEDLQRVQNYEGQYNDAQAKIKQLAQYIQELEKQLQDQMNQ 301

Query: 1264 FESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQ-NKLQDKEEHLRNLQEKYADVINQIEI 1322
            +E + ++LL++ +++  E+ + I  +E+  S + N+L+ + + +  LQ++  D  N+ + 
Sbjct: 302  YEKQIKELLNNAKATEDEKDHNIDQLEKDNSNKANQLEAQNKQISQLQKELKDADNKRD- 360

Query: 1323 LRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSX 1382
               E++D +                    L   N++ K   ++    IN  N +L +   
Sbjct: 361  --REVKDVQRKLDAELKKTAT--------LDKNNKTLKDKNDEQAKQINAANEELDQLDQ 410

Query: 1383 XXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLV 1442
                       ++ D E KV +  +Q++  + EI     E    L Q N+   N+ Q+  
Sbjct: 411  -----------KIADLEQKVKDQQNQIKDLEKEIKDLNKEKQ-NLIQDNN---NLHQKFN 455

Query: 1443 EYEKRIEDLTYEKESELAILRLKMHENANHYETMQK---ESEIERVKLIEELNVKITESV 1499
            + E++      +++ +L   + ++++  N+ E + K   E E E  +L +E+N    +  
Sbjct: 456  QAEEK----ALQQQKDLVKAQKELNDKHNNAEQLNKDLDEYEQENKELQKEINSLNDQIN 511

Query: 1500 SLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVS 1559
             LNK++ +  K ++++     ++Q  LE Q+ +  +   E   LQ     +++ + K ++
Sbjct: 512  QLNKEINQKQKQIDQQAKDIQKLQENLEKQKQDNQSKQQENKQLQQ----NNNDLNKQLN 567

Query: 1560 FASDTKQGRDEQLDNTMNKE 1579
             +    Q   +Q++NT  K+
Sbjct: 568  ESKKQNQKLQDQINNTEQKQ 587


>UniRef50_A0NCN7 Cluster: ENSANGP00000031886; n=1; Anopheles gambiae
            str. PEST|Rep: ENSANGP00000031886 - Anopheles gambiae
            str. PEST
          Length = 1029

 Score =  127 bits (307), Expect = 2e-27
 Identities = 197/905 (21%), Positives = 395/905 (43%), Gaps = 99/905 (10%)

Query: 472  TEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIK--- 528
            T   +  AK+   L+    +E     + D +E+  +    +T  N E+D   K + +   
Sbjct: 146  TSKASTDAKIAALLQSLDANEQNKAQLADNLEREMAKTRNLTSRNTELDVVKKQLTEELE 205

Query: 529  -VKSNHKLKLKQMQKTIDNF----SKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQL 583
             VK++       +Q+++D      ++++D+ ++ +  T +L+ L++   ELE EK  L  
Sbjct: 206  LVKTSMHESNAGLQRSLDALEHTKTQLADNLEQEMAKTADLNRLTE---ELEAEKKQLMQ 262

Query: 584  HLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDK 643
             L       M E +V K  +  EN AE + +++  +E  K  L           D +E +
Sbjct: 263  ELEIQKKQLMQELEVAKTSMS-ENNAELQ-RSLKAIEQTKMQLA----------DNLEKE 310

Query: 644  LADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDK 703
            +A  + L       E++   L ++++    SK       EN+     +L  +++ +E  K
Sbjct: 311  IAKTADLNRRTEELEVEKKQLTQELEVAKTSKS------ENI----AELQRSLEAIEQTK 360

Query: 704  EDIMNKLQNYIQENMDLTDKLEKMSAEK---ISELLAKINHEEQSKIQTQFGIDAKIQER 760
              + + L+  I +  DL  + EK+  EK   + EL        ++  + Q  ++A  Q +
Sbjct: 361  LQLADNLEKEIAKTADLNRRTEKLEVEKKQLMQELEVAKTSMSENIAELQRSLEAIEQTK 420

Query: 761  DLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGS----YLQEKQKAYSEY 816
              + +N+E E++K      R EE     +     LE  A   GS     LQ+  KA  + 
Sbjct: 421  LQFADNLEKEIAKTADLNRRTEELEVEKKQLTQELE-VAKSSGSENIAELQQSLKAIEQT 479

Query: 817  TIQ-EDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQH 875
             +Q  D L   +A   D +R  EK  +E +   +EL+     + E    LQ SL  ++Q 
Sbjct: 480  KLQLADNLEKEIAKTTDLNRRTEKLEVEKKQLMQELEVAKTSMSENIAELQQSLKAIEQT 539

Query: 876  Y-----NALVEKANRTDLAESESTKYQTQLRDLESNL---KRITHEHQTLIVQKKKEIED 927
                  N   E A  TDL    + K + + + L   L   K    E+   + +  K IE 
Sbjct: 540  KLQLADNLEKEIAKTTDL-NRRTEKLEVEKKQLMQELEVAKTSMSENNAELQRSLKAIEL 598

Query: 928  LEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLE 987
             +++    +E  I     LN + E   E   + +  LQE +    +++ N+ EL +    
Sbjct: 599  TKLQLADNLEKEIAKTADLNRRTE---ELEVEKKQLLQELEVAKTSMSENIAELQRSL-- 653

Query: 988  LIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIA-LNQKINNAQVSYMSMVSDY 1046
               K +++ + Q  D  E+ I +  +LN + K  + E IA L + +   + + + +  + 
Sbjct: 654  ---KAIEQTKLQLADNLEKEIAKTAELNQVAKSSESENIAELQRSLEAIEQTKLQLADNL 710

Query: 1047 ESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNI 1106
            E ++A+ T  L    EE++   KQLL      +EL++    + + I EL+++    E   
Sbjct: 711  EKEIAK-TADLNRRTEELEVEKKQLL------QELEVAKTSKSESIAELQQSLEAIEQT- 762

Query: 1107 PKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNT 1166
                 + +++ +E   + A   D             ++ +E E    ++ + E +A+L  
Sbjct: 763  ----KLQLANNLE--KEIAKTADLNRRTEELEAEKKQLMQELEV--AKTSMSENNAELQR 814

Query: 1167 ELQEC-YTKIIQLETLNTELTGHDVVNQ--EQINQLKSKL-EQLNTENDNLLSTVAELRS 1222
             L+    TK+   + L  E+     +N+  E++   K +L ++L     +    +AEL+ 
Sbjct: 815  SLKAIEQTKLQLADNLEKEIAKTAELNRRTEELEVEKKQLTQELEVAKSSGSENIAELQQ 874

Query: 1223 SISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQ----------LSAFESKYEQLL 1272
            S+  A++Q   ++A+  ++ +  + AD  +   EL V+          +    +   Q L
Sbjct: 875  SL-KAIEQTKLQLADNLEKEIT-KTADLNRRTEELEVEKKQLTQELDDMKTTNASLRQSL 932

Query: 1273 DSVQSSTQEETNKI-VTMEQVTSLQNKLQDKEEHLRNLQEKYAD-----VINQIEILRSE 1326
            + ++ +  + TN + + + ++  LQ++L+  +E  + L EK  D     ++ +I +L+  
Sbjct: 933  EVLELTKTQITNSLELELVKIGDLQHQLKAMDE-AKTLAEKLGDSERSEMLAKISLLQQN 991

Query: 1327 IEDEK 1331
            +E+E+
Sbjct: 992  LEEER 996



 Score =  122 bits (293), Expect = 1e-25
 Identities = 182/839 (21%), Positives = 358/839 (42%), Gaps = 49/839 (5%)

Query: 298  QSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESK 357
            +SIE   EE +  +E  S E+     + K+   LE  N  ++ T + L  +LA     ++
Sbjct: 75   RSIEALEEELSRAKETASTEMERYRAMKKQYATLEEDNQLMKLTAEALREELAAKDGANQ 134

Query: 358  AVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSL 417
             ++   K+        S  +T +K+ +    L +   N+       + E+AK    + S 
Sbjct: 135  NLAEALKEEF----ETSKASTDAKIAALLQSLDANEQNKAQLADNLEREMAKTRN-LTSR 189

Query: 418  NKDL-VDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVN 476
            N +L V K+ +  E +           G    +  L  EH +     +L      T D+N
Sbjct: 190  NTELDVVKKQLTEELELVKTSMHESNAGLQRSLDAL--EHTKTQLADNLEQEMAKTADLN 247

Query: 477  EIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLK 536
             + +  E  K++L  E+ ++  K L+++L+ A+  +++ N E+  + K + + K      
Sbjct: 248  RLTEELEAEKKQLMQEL-EIQKKQLMQELEVAKTSMSENNAELQRSLKAIEQTKMQLADN 306

Query: 537  L-KQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIE 595
            L K++ KT D   +  +   E  +LT+EL     K ++  E    LQ  L   +  ++  
Sbjct: 307  LEKEIAKTADLNRRTEELEVEKKQLTQELE--VAKTSK-SENIAELQRSLEAIEQTKLQL 363

Query: 596  SDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHI----LQQKYDEVEDKLADISQLQ 651
            +D  +K  E+   A+   +    LE +K  L+QEL +    + +   E++  L  I Q +
Sbjct: 364  ADNLEK--EIAKTADLN-RRTEKLEVEKKQLMQELEVAKTSMSENIAELQRSLEAIEQTK 420

Query: 652  ---SDQVCSEI-KSVHLEEQIDALSASKKELALVIENLKLDKE----QLYGTIKDLENDK 703
               +D +  EI K+  L  + + L   KK+L   +E  K        +L  ++K +E  K
Sbjct: 421  LQFADNLEKEIAKTADLNRRTEELEVEKKQLTQELEVAKSSGSENIAELQQSLKAIEQTK 480

Query: 704  EDIMNKLQNYIQENMDLTDKLEKMSAEK---ISELLAKINHEEQSKIQTQFGIDAKIQER 760
              + + L+  I +  DL  + EK+  EK   + EL        ++  + Q  + A  Q +
Sbjct: 481  LQLADNLEKEIAKTTDLNRRTEKLEVEKKQLMQELEVAKTSMSENIAELQQSLKAIEQTK 540

Query: 761  DLYIENIESELSK---YKSRICRLE-ESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEY 816
                +N+E E++K      R  +LE E   +M++   + +    +  + LQ   KA    
Sbjct: 541  LQLADNLEKEIAKTTDLNRRTEKLEVEKKQLMQELEVA-KTSMSENNAELQRSLKAIELT 599

Query: 817  TIQ-EDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQH 875
             +Q  D L   +A   D +R  E+  +E +   +EL+     + E    LQ SL  ++Q 
Sbjct: 600  KLQLADNLEKEIAKTADLNRRTEELEVEKKQLLQELEVAKTSMSENIAELQRSLKAIEQT 659

Query: 876  Y-----NALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEI 930
                  N   E A   +L +   +     + +L+ +L+ I      L    +KEI     
Sbjct: 660  KLQLADNLEKEIAKTAELNQVAKSSESENIAELQRSLEAIEQTKLQLADNLEKEIAK-TA 718

Query: 931  EFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNV-EELNKMNLELI 989
            + N + E    +KK L ++ E      ++  A+LQ+    IE   + +   L K   +  
Sbjct: 719  DLNRRTEELEVEKKQLLQELEVAKTSKSESIAELQQSLEAIEQTKLQLANNLEKEIAKTA 778

Query: 990  DKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESK 1049
            D + + ++ ++    +Q + E+      + + + E+    + I   ++     +    +K
Sbjct: 779  DLNRRTEELEAE--KKQLMQELEVAKTSMSENNAELQRSLKAIEQTKLQLADNLEKEIAK 836

Query: 1050 LAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPK 1108
             A+   + E +E E ++++++L  +K    E    + E    +K +++TKL    N+ K
Sbjct: 837  TAELNRRTEELEVEKKQLTQELEVAKSSGSE---NIAELQQSLKAIEQTKLQLADNLEK 892



 Score =  107 bits (256), Expect = 3e-21
 Identities = 178/911 (19%), Positives = 385/911 (42%), Gaps = 75/911 (8%)

Query: 237  QRLLKDIESKDVRISSL-EEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXL 295
            ++L K +ESK+  I +L EE ++  E A  E+    +   Q                   
Sbjct: 64   EQLQKQLESKNRSIEALEEELSRAKETASTEMERYRAMKKQYATLEEDNQLMKLTAEALR 123

Query: 296  AKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTE 355
             + + +    +      K   E +  +   K   LL+ L+    Q   +L + L     +
Sbjct: 124  EELAAKDGANQNLAEALKEEFETSKASTDAKIAALLQSLDAN-EQNKAQLADNLEREMAK 182

Query: 356  SKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQ 415
            ++ ++S + +    + +K        +K+     S    N    + ++  E  K ++   
Sbjct: 183  TRNLTSRNTELD--VVKKQLTEELELVKT-----SMHESNAGLQRSLDALEHTKTQLA-- 233

Query: 416  SLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSL--IHVGTNTE 473
                D +++E  +++              K  L+ +L+++ +Q M+   +    +  N  
Sbjct: 234  ----DNLEQE--MAKTADLNRLTEELEAEKKQLMQELEIQKKQLMQELEVAKTSMSENNA 287

Query: 474  DVNEIAKVQEQLKQELNDEI-KDV-NVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKS 531
            ++    K  EQ K +L D + K++    DL  + +  E +  QL  E++ A  +  +  +
Sbjct: 288  ELQRSLKAIEQTKMQLADNLEKEIAKTADLNRRTEELEVEKKQLTQELEVAKTSKSENIA 347

Query: 532  NHKLKLKQMQKT----IDNFSKVSDSNKEIVRLTEELH-HLSQKVAELEEEKGNLQLHLV 586
              +  L+ +++T     DN  K      ++ R TE+L     Q + ELE  K ++  ++ 
Sbjct: 348  ELQRSLEAIEQTKLQLADNLEKEIAKTADLNRRTEKLEVEKKQLMQELEVAKTSMSENIA 407

Query: 587  DYDSGRMIESDVYKKMIEMENLAETRLKAISL------LESQKFDLVQELHILQ----QK 636
            +    R +E+    K+   +NL +   K   L      LE +K  L QEL + +    + 
Sbjct: 408  ELQ--RSLEAIEQTKLQFADNLEKEIAKTADLNRRTEELEVEKKQLTQELEVAKSSGSEN 465

Query: 637  YDEVEDKLADISQLQ---SDQVCSEI-KSVHLEEQIDALSASKKELALVIENLKLDKE-- 690
              E++  L  I Q +   +D +  EI K+  L  + + L   KK+L   +E  K      
Sbjct: 466  IAELQQSLKAIEQTKLQLADNLEKEIAKTTDLNRRTEKLEVEKKQLMQELEVAKTSMSEN 525

Query: 691  --QLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQ 748
              +L  ++K +E  K  + + L+  I +  DL  + EK+  EK  +L+ ++   + S  +
Sbjct: 526  IAELQQSLKAIEQTKLQLADNLEKEIAKTTDLNRRTEKLEVEK-KQLMQELEVAKTSMSE 584

Query: 749  TQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQE 808
                 +A++Q     IE  + +L+        LE+ IA   D    L R+ ++L     E
Sbjct: 585  N----NAELQRSLKAIELTKLQLAD------NLEKEIAKTAD----LNRRTEELE---VE 627

Query: 809  KQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEI-EHENKELQKKNQILLEENQNLQI 867
            K++   E  + +  +   +A L    + +E+  L++ ++  KE+ K  ++      +   
Sbjct: 628  KKQLLQELEVAKTSMSENIAELQRSLKAIEQTKLQLADNLEKEIAKTAELNQVAKSSESE 687

Query: 868  SLSDMQQHYNALVE-KANRTDLAESESTK---YQTQLRDLESNLKRITHEHQTLIVQKKK 923
            +++++Q+   A+ + K    D  E E  K      +  +LE   K++  E +     K +
Sbjct: 688  NIAELQRSLEAIEQTKLQLADNLEKEIAKTADLNRRTEELEVEKKQLLQELEVAKTSKSE 747

Query: 924  EIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEY---VTQLEAQLQEYKNNIENLNMNVEE 980
             I +L+       ++ ++    L ++  K  +      +LEA+ ++    +E    ++ E
Sbjct: 748  SIAELQQSLEAIEQTKLQLANNLEKEIAKTADLNRRTEELEAEKKQLMQELEVAKTSMSE 807

Query: 981  LNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYM 1040
             N   L+   K +++ + Q  D  E+ I +  +LN   ++ + E   L Q++  A+ S  
Sbjct: 808  -NNAELQRSLKAIEQTKLQLADNLEKEIAKTAELNRRTEELEVEKKQLTQELEVAKSSGS 866

Query: 1041 SMVSDYESKL-AQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETK 1099
              +++ +  L A   TKL+ + + +++   +  D  +  EEL++  ++   ++ ++K T 
Sbjct: 867  ENIAELQQSLKAIEQTKLQ-LADNLEKEITKTADLNRRTEELEVEKKQLTQELDDMKTTN 925

Query: 1100 LTFEMNIPKTE 1110
             +   ++   E
Sbjct: 926  ASLRQSLEVLE 936



 Score =  105 bits (252), Expect = 1e-20
 Identities = 202/965 (20%), Positives = 389/965 (40%), Gaps = 93/965 (9%)

Query: 621  SQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELAL 680
            SQ+  + Q L  +Q+  +E    LA IS L+  + C     V + + +D L+     L  
Sbjct: 10   SQERQIEQLLQSVQELQEEKRRNLAKISALELKEAC-----VCMSDAVDYLA---HPLGR 61

Query: 681  VIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSA--EKISELLAK 738
              E L+   E    +I+ LE +    +++ +      M+    ++K  A  E+ ++L+  
Sbjct: 62   ATEQLQKQLESKNRSIEALEEE----LSRAKETASTEMERYRAMKKQYATLEEDNQLMKL 117

Query: 739  INHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERK 798
                 + ++  + G +  + E     E  E+  +   ++I  L +S+   E      + K
Sbjct: 118  TAEALREELAAKDGANQNLAEA--LKEEFETSKASTDAKIAALLQSLDANE------QNK 169

Query: 799  ADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQIL 858
            A QL   L+ +       T +  EL            VV+KQL E      EL+     +
Sbjct: 170  A-QLADNLEREMAKTRNLTSRNTEL-----------DVVKKQLTE------ELELVKTSM 211

Query: 859  LEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLI 918
             E N  LQ SL  ++     L +   + ++A++      T+  +LE+  K++  E   L 
Sbjct: 212  HESNAGLQRSLDALEHTKTQLADNLEQ-EMAKTADLNRLTE--ELEAEKKQLMQE---LE 265

Query: 919  VQKKKEIEDLEI------EFNTQIESAIR----DKKVLNEKYEKNIEYVTQLEAQLQEYK 968
            +QKK+ +++LE+      E N +++ +++     K  L +  EK I     L  + +E +
Sbjct: 266  IQKKQLMQELEVAKTSMSENNAELQRSLKAIEQTKMQLADNLEKEIAKTADLNRRTEELE 325

Query: 969  NNIENLNMNVEELNKMNLELIDK------HVQKQQTQSPDYTEQYINEINKLNALLKQKD 1022
               + L   +E       E I +       +++ + Q  D  E+ I +   LN   ++ +
Sbjct: 326  VEKKQLTQELEVAKTSKSENIAELQRSLEAIEQTKLQLADNLEKEIAKTADLNRRTEKLE 385

Query: 1023 EEIIALNQKINNAQVSYMSMVSDYESKLAQFT-TKLENMEEEMQRVSKQLLDSKQHNEEL 1081
             E   L Q++  A+ S    +++ +  L     TKL+  +   + ++K   D  +  EEL
Sbjct: 386  VEKKQLMQELEVAKTSMSENIAELQRSLEAIEQTKLQFADNLEKEIAKTA-DLNRRTEEL 444

Query: 1082 QILVREQDDQIKELKETKLTFEMNIPKTEGMI--ISSTIEPMSDDANNVDXXXXXXXXXX 1139
            ++   E+    +EL+  K +   NI + +  +  I  T   ++D+               
Sbjct: 445  EV---EKKQLTQELEVAKSSGSENIAELQQSLKAIEQTKLQLADNLEKEIAKTTDLNRRT 501

Query: 1140 XXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQL 1199
              L+V E+++ +QE  V +   ++   ELQ+    I Q +    +    ++     +N+ 
Sbjct: 502  EKLEV-EKKQLMQELEVAKTSMSENIAELQQSLKAIEQTKLQLADNLEKEIAKTTDLNRR 560

Query: 1200 KSKLEQLNTENDNLLSTVAELRSSIS--SAVDQRGFEIAELWKQHLAQ-------READF 1250
              KLE    E   L+  +   ++S+S  +A  QR  +  EL K  LA        + AD 
Sbjct: 561  TEKLE---VEKKQLMQELEVAKTSMSENNAELQRSLKAIELTKLQLADNLEKEIAKTADL 617

Query: 1251 QKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVT-SLQNKLQDKEEHLRNL 1309
             +   EL V+      + E    S+  +  E    +  +EQ    L + L+ +      L
Sbjct: 618  NRRTEELEVEKKQLLQELEVAKTSMSENIAELQRSLKAIEQTKLQLADNLEKEIAKTAEL 677

Query: 1310 QE--KYADVINQIEILRS--EIEDEKVAFXXXXXXXXXXXXXX---XXDLRTENQSYKQM 1362
             +  K ++  N  E+ RS   IE  K+                     +L  E +   Q 
Sbjct: 678  NQVAKSSESENIAELQRSLEAIEQTKLQLADNLEKEIAKTADLNRRTEELEVEKKQLLQE 737

Query: 1363 QEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHE 1422
             E +  + +E  A+L++S              +    AK  +L  + E  ++E  Q   E
Sbjct: 738  LEVAKTSKSESIAELQQSLEAIEQTKLQLANNLEKEIAKTADLNRRTEELEAEKKQLMQE 797

Query: 1423 YTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELA-ILRLKMHENANHYETMQKESE 1481
              +  T  ++    +++ L   E+    L    E E+A    L         E  Q   E
Sbjct: 798  LEVAKTSMSENNAELQRSLKAIEQTKLQLADNLEKEIAKTAELNRRTEELEVEKKQLTQE 857

Query: 1482 IERVKLIEELNV-KITESVSLNKQVA-ELNKALEEEVAKTNEMQTALENQEIEIVTLNDE 1539
            +E  K     N+ ++ +S+   +Q   +L   LE+E+ KT ++    E  E+E   L  E
Sbjct: 858  LEVAKSSGSENIAELQQSLKAIEQTKLQLADNLEKEITKTADLNRRTEELEVEKKQLTQE 917

Query: 1540 ITNLQ 1544
            + +++
Sbjct: 918  LDDMK 922



 Score = 99.1 bits (236), Expect = 9e-19
 Identities = 164/848 (19%), Positives = 351/848 (41%), Gaps = 66/848 (7%)

Query: 764  IENIESELSKYKSRICRLE--ESIAVMEDR----RYSLERKADQLGSYLQEKQKAYSEYT 817
            ++ ++ E  +  ++I  LE  E+   M D      + L R  +QL   L+ K ++     
Sbjct: 22   VQELQEEKRRNLAKISALELKEACVCMSDAVDYLAHPLGRATEQLQKQLESKNRSIEALE 81

Query: 818  IQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEE-------NQNLQISLS 870
             +        +  M+  R ++KQ   +E +N+ ++   + L EE       NQNL  +L 
Sbjct: 82   EELSRAKETASTEMERYRAMKKQYATLEEDNQLMKLTAEALREELAAKDGANQNLAEALK 141

Query: 871  DMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEI 930
            +  +   A  + A    L +S     Q + + L  NL+R   + + L   +  E++ ++ 
Sbjct: 142  EEFETSKASTD-AKIAALLQSLDANEQNKAQ-LADNLEREMAKTRNL-TSRNTELDVVKK 198

Query: 931  EFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELID 990
            +   ++E         N   +++++ +   + QL +   N+E       +LN++  EL  
Sbjct: 199  QLTEELELVKTSMHESNAGLQRSLDALEHTKTQLAD---NLEQEMAKTADLNRLTEELEA 255

Query: 991  KHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKL 1050
            +  Q  Q +     +Q + E+      + + + E   L + +   + + M +  + E ++
Sbjct: 256  EKKQLMQ-ELEIQKKQLMQELEVAKTSMSENNAE---LQRSLKAIEQTKMQLADNLEKEI 311

Query: 1051 AQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTE 1110
            A+ T  L    EE++      ++ KQ  +EL++    + + I EL+ +    E       
Sbjct: 312  AK-TADLNRRTEELE------VEKKQLTQELEVAKTSKSENIAELQRSLEAIEQT----- 359

Query: 1111 GMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQE 1170
             + ++  +E   + A   D             ++ +E E    ++ + E  A+L   L+ 
Sbjct: 360  KLQLADNLE--KEIAKTADLNRRTEKLEVEKKQLMQELEVA--KTSMSENIAELQRSLEA 415

Query: 1171 C-YTKIIQLETLNTELTGHDVVNQ--EQINQLKSKLEQ-LNTENDNLLSTVAELRSSISS 1226
               TK+   + L  E+     +N+  E++   K +L Q L     +    +AEL+ S+  
Sbjct: 416  IEQTKLQFADNLEKEIAKTADLNRRTEELEVEKKQLTQELEVAKSSGSENIAELQQSLK- 474

Query: 1227 AVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKI 1286
            A++Q   ++A+  ++ +A +  D  +   +L V+      + E    S+  +  E    +
Sbjct: 475  AIEQTKLQLADNLEKEIA-KTTDLNRRTEKLEVEKKQLMQELEVAKTSMSENIAELQQSL 533

Query: 1287 VTMEQVT-SLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXX 1345
              +EQ    L + L+ +     +L  +   +  + + L  E+E  K +            
Sbjct: 534  KAIEQTKLQLADNLEKEIAKTTDLNRRTEKLEVEKKQLMQELEVAKTSMSENNAELQRSL 593

Query: 1346 XXXX-XDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEA-KVL 1403
                   L+  +   K++ + + LN   E  +++K                N AE  + L
Sbjct: 594  KAIELTKLQLADNLEKEIAKTADLNRRTEELEVEKKQLLQELEVAKTSMSENIAELQRSL 653

Query: 1404 ELTHQLELKDSEIYQKTHEYTITLTQ--RNDEFENVRQQLVEYEKRIEDLTYEKESELAI 1461
            +   Q +L+ ++  +K    T  L Q  ++ E EN+     E ++ +E +   K      
Sbjct: 654  KAIEQTKLQLADNLEKEIAKTAELNQVAKSSESENI----AELQRSLEAIEQTKLQLADN 709

Query: 1462 LRLKMHENANHYETMQKESEIERVKLIEELNVKIT---ESVSLNKQVAE--------LNK 1510
            L  ++ + A+      +E E+E+ +L++EL V  T   ES++  +Q  E        L  
Sbjct: 710  LEKEIAKTAD-LNRRTEELEVEKKQLLQELEVAKTSKSESIAELQQSLEAIEQTKLQLAN 768

Query: 1511 ALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDE 1570
             LE+E+AKT ++    E  E E   L  E+   +  +  +++++Q+ +     TK    +
Sbjct: 769  NLEKEIAKTADLNRRTEELEAEKKQLMQELEVAKTSMSENNAELQRSLKAIEQTKLQLAD 828

Query: 1571 QLDNTMNK 1578
             L+  + K
Sbjct: 829  NLEKEIAK 836



 Score = 81.8 bits (193), Expect = 1e-13
 Identities = 158/747 (21%), Positives = 315/747 (42%), Gaps = 65/747 (8%)

Query: 212  EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRIS-SLE-EANKLLEAARF--EI 267
            E  K+Q+T+  E     ++E   E QR L+ IE   ++++ +LE E  K  +  R   ++
Sbjct: 325  EVEKKQLTQELEVAKTSKSENIAELQRSLEAIEQTKLQLADNLEKEIAKTADLNRRTEKL 384

Query: 268  SLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKK 327
             +E  +L QELE                 ++S+E   + K +  +    EIA   +L ++
Sbjct: 385  EVEKKQLMQELEVAKTSMSENIAEL----QRSLEAIEQTKLQFADNLEKEIAKTADLNRR 440

Query: 328  IELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWS 387
             E LE    + +Q  +ELE   ++ G+E+ A    S K       +   N   ++    +
Sbjct: 441  TEELE---VEKKQLTQELEVAKSS-GSENIAELQQSLKAIEQTKLQLADNLEKEIAKT-T 495

Query: 388  QLSSETLNQDTDKK--INKNEIAKLEMV--IQSLNKDLVDKEYVISEKDTXXXXXXXXXX 443
             L+  T   + +KK  + + E+AK  M   I  L + L   E    +             
Sbjct: 496  DLNRRTEKLEVEKKQLMQELEVAKTSMSENIAELQQSLKAIEQTKLQLADNLEKEIAKTT 555

Query: 444  GKDTLIAQLQLEHQQHMEGPSLIH--VGTNTEDVNEIAKVQEQLKQELNDEIKDVNVK-- 499
              +    +L++E +Q M+   +    +  N  ++    K  E  K +L D ++    K  
Sbjct: 556  DLNRRTEKLEVEKKQLMQELEVAKTSMSENNAELQRSLKAIELTKLQLADNLEKEIAKTA 615

Query: 500  DLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVR 559
            DL  + +  E +  QL  E++ A  +M +  +  +  LK +++T        +  KEI +
Sbjct: 616  DLNRRTEELEVEKKQLLQELEVAKTSMSENIAELQRSLKAIEQT--KLQLADNLEKEIAK 673

Query: 560  LTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLL 619
             T EL+ ++ K +E  E    LQ  L   +  ++  +D  +K  E+   A+   +   L 
Sbjct: 674  -TAELNQVA-KSSE-SENIAELQRSLEAIEQTKLQLADNLEK--EIAKTADLNRRTEEL- 727

Query: 620  ESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELA 679
            E +K  L+QEL + +    E       I++LQ      E   + L   ++   A   +L 
Sbjct: 728  EVEKKQLLQELEVAKTSKSE------SIAELQQSLEAIEQTKLQLANNLEKEIAKTADLN 781

Query: 680  LVIENLKLDKEQLYGTIK----DLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISEL 735
               E L+ +K+QL   ++     +  +  ++   L+   Q  + L D LEK  A+     
Sbjct: 782  RRTEELEAEKKQLMQELEVAKTSMSENNAELQRSLKAIEQTKLQLADNLEKEIAK----- 836

Query: 736  LAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSL 795
             A++N   +         + +++++ L  + +E   S     I  L++S+  +E  +  L
Sbjct: 837  TAELNRRTE---------ELEVEKKQL-TQELEVAKSSGSENIAELQQSLKAIEQTKLQL 886

Query: 796  ERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKN 855
                ++  +   +  +   E  +++ +L   L  +   +  + +Q LE+  E  + Q  N
Sbjct: 887  ADNLEKEITKTADLNRRTEELEVEKKQLTQELDDMKTTNASL-RQSLEV-LELTKTQITN 944

Query: 856  QILLEENQNLQISLSDMQQHYNALVE-KANRTDLAESESTKYQTQLRDLESNLKRITHEH 914
             + LE      + + D+Q    A+ E K     L +SE ++   ++  L+ NL+    + 
Sbjct: 945  SLELE-----LVKIGDLQHQLKAMDEAKTLAEKLGDSERSEMLAKISLLQQNLEEEREKS 999

Query: 915  QTLIVQ---KKKEIEDLEIEFNTQIES 938
              +  Q    K++ +DL+ +    ++S
Sbjct: 1000 DEINCQYLAMKRQADDLDAQCTKLMKS 1026



 Score = 71.7 bits (168), Expect = 2e-10
 Identities = 127/637 (19%), Positives = 243/637 (38%), Gaps = 36/637 (5%)

Query: 947  NEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQ 1006
            N   E+ IE + Q   +LQE K        N+ +++ + L    K      + + DY   
Sbjct: 8    NTSQERQIEQLLQSVQELQEEKRR------NLAKISALEL----KEACVCMSDAVDYLAH 57

Query: 1007 YINEINK-LNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQ 1065
             +    + L   L+ K+  I AL ++++ A+ +  + +  Y +   Q+ T    +EE+ Q
Sbjct: 58   PLGRATEQLQKQLESKNRSIEALEEELSRAKETASTEMERYRAMKKQYAT----LEEDNQ 113

Query: 1066 RVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDA 1125
             +    L ++   EEL        +  + LKE    FE +   T+  I +      S DA
Sbjct: 114  LMK---LTAEALREELAAKDGANQNLAEALKEE---FETSKASTDAKIAALL---QSLDA 164

Query: 1126 NNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTEL 1185
            N  +             K +       E  V+++Q   L  EL+   T    +   N  L
Sbjct: 165  NEQNKAQLADNLEREMAKTRNLTSRNTELDVVKKQ---LTEELELVKTS---MHESNAGL 218

Query: 1186 TGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQ 1245
                   +    QL   LEQ   +  +L     EL +     + +   +  +L  Q L  
Sbjct: 219  QRSLDALEHTKTQLADNLEQEMAKTADLNRLTEELEAEKKQLMQELEIQKKQLM-QELEV 277

Query: 1246 READFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKL-QDKEE 1304
             +    +   EL+  L A E    QL D+++    +  +     E++   + +L Q+ E 
Sbjct: 278  AKTSMSENNAELQRSLKAIEQTKMQLADNLEKEIAKTADLNRRTEELEVEKKQLTQELEV 337

Query: 1305 HLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQE 1364
               +  E  A++   +E +  + + +                     L  E +   Q  E
Sbjct: 338  AKTSKSENIAELQRSLEAIE-QTKLQLADNLEKEIAKTADLNRRTEKLEVEKKQLMQELE 396

Query: 1365 QSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYT 1424
             +  +++E  A+L++S              +    AK  +L  + E  + E  Q T E  
Sbjct: 397  VAKTSMSENIAELQRSLEAIEQTKLQFADNLEKEIAKTADLNRRTEELEVEKKQLTQELE 456

Query: 1425 ITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELA-ILRLKMHENANHYETMQKESEIE 1483
            +  +  ++    ++Q L   E+    L    E E+A    L         E  Q   E+E
Sbjct: 457  VAKSSGSENIAELQQSLKAIEQTKLQLADNLEKEIAKTTDLNRRTEKLEVEKKQLMQELE 516

Query: 1484 RVKLIEELNV-KITESVSLNKQVA-ELNKALEEEVAKTNEMQTALENQEIEIVTLNDEIT 1541
              K     N+ ++ +S+   +Q   +L   LE+E+AKT ++    E  E+E   L  E+ 
Sbjct: 517  VAKTSMSENIAELQQSLKAIEQTKLQLADNLEKEIAKTTDLNRRTEKLEVEKKQLMQELE 576

Query: 1542 NLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNK 1578
              +  +  +++++Q+ +     TK    + L+  + K
Sbjct: 577  VAKTSMSENNAELQRSLKAIELTKLQLADNLEKEIAK 613


>UniRef50_A2DGV9 Cluster: Viral A-type inclusion protein, putative;
            n=1; Trichomonas vaginalis G3|Rep: Viral A-type inclusion
            protein, putative - Trichomonas vaginalis G3
          Length = 1150

 Score =  127 bits (306), Expect = 3e-27
 Identities = 216/1079 (20%), Positives = 471/1079 (43%), Gaps = 78/1079 (7%)

Query: 473  EDVNEIAKVQEQLKQELNDE-IKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKS 531
            + + E+ K Q Q+  EL +  I D N   +   + S     T +  E      N+  V  
Sbjct: 49   QSLYELFKQQIQMYNELKEAYINDTNSYSVT--ITSINNLYTYIQQEFGQKVDNIDSVLK 106

Query: 532  NHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSG 591
              K K+K   +++D          +I +L  E  HL  K+ E  ++ G+L+  +      
Sbjct: 107  IFKEKVKSSNESVDLQKNEKSLKHQIKKLQRENSHLQDKLNE-RDKSGDLRRKI------ 159

Query: 592  RMIESDVYKKMIEMENLAETRLKAISLLESQKFD---LVQELHILQQK-YDEVEDKLADI 647
            + +++D+  K  E++ L  T  +     E QK D   L  + H LQ+     V+ K  +I
Sbjct: 160  QSLKNDMDSKETEIKQLNSTLKEIKQKFEKQKQDNEKLRNDYHELQETVVTSVDTKTEEI 219

Query: 648  SQLQSDQVCSEIKSVHLE-EQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDI 706
                 D   S++  +  E EQ+    +  ++ A   ++L++ +E +  T K LE  ++ +
Sbjct: 220  R--PDDIRMSQLSQLQRENEQLQHKISILEDEAQ--KSLEISQEDMKKT-KGLEKSQQIL 274

Query: 707  MNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIEN 766
             ++L +  ++  +L ++L +++ +K   +   +   ++   + +  +D K  E +  I  
Sbjct: 275  QSQLDDANEDIKNLNEEL-RLANQKTQSIEKSMRSLQRENSELKAKLDEKDAEHETTISE 333

Query: 767  IESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDEL--V 824
            ++ E++K  S I ++    + +ED +  + R  D+L    +E +   SE    + ++   
Sbjct: 334  MKGEIAKSDSNIRKIASLNSKIEDYQEEITRINDELAQTHEELRTVTSENARLKTKVGEF 393

Query: 825  NRLAVLMDHDRVVEKQLLEIEHENKELQKK-NQILLEENQNLQISLSDMQQHYNALVEKA 883
             R A L+  +R  ++Q   +E EN  L+ K N+  L+  Q+++ + ++ ++    + E  
Sbjct: 394  ERRASLLS-ERPSKEQFTVLEEENARLKSKINENQLKYQQSIETAQNENKELKQTISEIQ 452

Query: 884  NRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEI---EFNTQIESAI 940
            N+T     E T ++ +  D    LKRI  E  +L  Q K   +D +I   +  T  E A 
Sbjct: 453  NQTVQITKEKTSFEQENND----LKRIAGEVDSLKQQIKSLKQDNDILKDKLQTAEEKAS 508

Query: 941  RDKKVLN--EKYEKNIEYVTQ-LEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQ 997
              +K  +  E+ + +   + Q +    +++KN+I  L     +L +   +L D+   KQ 
Sbjct: 509  NTQKAQSSFERLQNDYRNLKQEVNENTEKHKNSISQLKKENSQLKETIEDLEDQIHAKQN 568

Query: 998  T--QSPDYTEQYINEINKLNA-------LLKQKDEEIIALNQKINNAQVSYMSMVSDYES 1048
            +  +         N I +L++       LL++K  E   L Q   +AQ S   + S  + 
Sbjct: 569  SLDREKSNNNNLRNTIEELHSKSLENSRLLEKKKAENEDLKQSYEDAQ-SKSIISSSQQR 627

Query: 1049 KLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPK 1108
             + +   +   + E ++ +  QL ++    + +Q L + +++++K   E+K    +   +
Sbjct: 628  SIDRLRNENNELRETIEDLQNQLGNNGSQTKTIQKL-KAENEELKAEMESKQNRSLERLR 686

Query: 1109 TEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTEL 1168
             E   +   I  + D    +               V+E     QE   L++QS      +
Sbjct: 687  NENRQLKQEIADL-DSKYQLSQSQLQST-------VKENAGLKQEIEDLEDQS------M 732

Query: 1169 QECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAV 1228
            Q    +I +L+  N +L   + +++ Q N+  ++L+    EN++L  T+ EL+S +S ++
Sbjct: 733  QNVSKEIDRLKNENLDL--KEKIDRLQNNRSSARLK---AENEDLKQTIEELKSQMSKSI 787

Query: 1229 DQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVT 1288
            D    E  EL +++    EA   K     +  +     + ++L   + S ++ +  K   
Sbjct: 788  DNLKSENRELRRKNSDLVEATQIKPTDVDQDTIEQLTRENDELRRKL-SLSKNDNEKSNL 846

Query: 1289 MEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXX 1348
            +EQVT+L+ K  +    +R++ E  A+  N  + ++ ++ D +                 
Sbjct: 847  IEQVTTLKEKNIELLMKMRDMMED-AENGNNNDQMKRQVSDLQRQNADLQRQLSESQRIL 905

Query: 1349 XXDLRTENQSYKQMQEQSILNINE------ENAQLKKSSXXXXXXXXXXXXRVNDAEAKV 1402
              + + ++ +   + +++I  I+E      E   LK+S             +  D     
Sbjct: 906  DNERQKKSVNDDTIDQKTIKLISENREMKLEIESLKRSISDYEKLIDFERQKRYDNSDDK 965

Query: 1403 LELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAIL 1462
             +++  ++ +++++     +  + L+++ +  ++VR+++   E ++  +  E  S     
Sbjct: 966  SKISRLID-ENNDLRSVIKDLNLKLSEKKEFADSVRRRIESIEAKVGYVANEFSSYKQRK 1024

Query: 1463 RLKMHENANHYET---MQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAK 1518
              + + N N+ E    +QKE++   V L+ +L  +I    ++  Q     K+L  E  K
Sbjct: 1025 SSQYNGNENNSEEVRYLQKENQ-RLVSLVSKLKCEIIGIRNIAAQQISSKKSLSPEEIK 1082



 Score =  110 bits (265), Expect = 3e-22
 Identities = 196/1040 (18%), Positives = 441/1040 (42%), Gaps = 124/1040 (11%)

Query: 589  DSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADIS 648
            +S + +E+ + K+  ++E    T  K      S  F ++Q L+ L ++  ++ ++L +  
Sbjct: 12   ESFKQLEAQISKQTQDIEEFISTHSKYHK--PSHTFQVLQSLYELFKQQIQMYNELKEAY 69

Query: 649  QLQSDQVCSEIKSVHLEEQIDALSASKKELALVIEN----LKLDKEQLYGTIK--DLEND 702
               ++     I S++     +  +  ++E    ++N    LK+ KE++  + +  DL+ +
Sbjct: 70   INDTNSYSVTITSIN-----NLYTYIQQEFGQKVDNIDSVLKIFKEKVKSSNESVDLQKN 124

Query: 703  KEDIMNKLQNYIQENMDLTDKL-EKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERD 761
            ++ + ++++   +EN  L DKL E+  +  +   +  + ++  SK      +++ ++E  
Sbjct: 125  EKSLKHQIKKLQRENSHLQDKLNERDKSGDLRRKIQSLKNDMDSKETEIKQLNSTLKEIK 184

Query: 762  LYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQED 821
               E  + +  K ++    L+E++    D +    R  D   S L + Q+       + +
Sbjct: 185  QKFEKQKQDNEKLRNDYHELQETVVTSVDTKTEEIRPDDIRMSQLSQLQR-------ENE 237

Query: 822  ELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVE 881
            +L +++++L D      ++ LEI  E+    KK + L +  Q LQ  L D  +    L E
Sbjct: 238  QLQHKISILEDE----AQKSLEISQED---MKKTKGLEKSQQILQSQLDDANEDIKNLNE 290

Query: 882  K---AN-RTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIE 937
            +   AN +T   E      Q +  +L++ L     EH+T I + K EI         + +
Sbjct: 291  ELRLANQKTQSIEKSMRSLQRENSELKAKLDEKDAEHETTISEMKGEI--------AKSD 342

Query: 938  SAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQ 997
            S IR    LN K E   E +T++  +L +    +  +      L       + +  ++  
Sbjct: 343  SNIRKIASLNSKIEDYQEEITRINDELAQTHEELRTVTSENARLKTK----VGEFERRAS 398

Query: 998  TQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKL 1057
              S   +++    + + NA LK K          IN  Q+ Y   +   +++  +    +
Sbjct: 399  LLSERPSKEQFTVLEEENARLKSK----------INENQLKYQQSIETAQNENKELKQTI 448

Query: 1058 ENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISST 1117
              ++ +  +++K+    +Q N +L+ +  E D   +++K           K +  I+   
Sbjct: 449  SEIQNQTVQITKEKTSFEQENNDLKRIAGEVDSLKQQIKSL---------KQDNDILKDK 499

Query: 1118 IEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQ 1177
            ++   + A+N               K Q   E +Q      +Q    NTE  +    I Q
Sbjct: 500  LQTAEEKASNTQ-------------KAQSSFERLQNDYRNLKQEVNENTEKHK--NSISQ 544

Query: 1178 LETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSI---SSAVDQRGFE 1234
            L+  N++L       ++QI+  ++ L++  + N+NL +T+ EL S     S  ++++  E
Sbjct: 545  LKKENSQLKETIEDLEDQIHAKQNSLDREKSNNNNLRNTIEELHSKSLENSRLLEKKKAE 604

Query: 1235 IAELWKQHL-AQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVT 1293
              +L + +  AQ ++    ++     +L    ++  + ++ +Q+      ++  T++++ 
Sbjct: 605  NEDLKQSYEDAQSKSIISSSQQRSIDRLRNENNELRETIEDLQNQLGNNGSQTKTIQKLK 664

Query: 1294 S----LQNKLQDKE----EHLRN----LQEKYADVINQIEILRSEIEDE-------KVAF 1334
            +    L+ +++ K+    E LRN    L+++ AD+ ++ ++ +S+++         K   
Sbjct: 665  AENEELKAEMESKQNRSLERLRNENRQLKQEIADLDSKYQLSQSQLQSTVKENAGLKQEI 724

Query: 1335 XXXXXXXXXXXXXXXXDLRTENQSYKQ-----MQEQSILNINEENAQLKKSSXXXXXXXX 1389
                             L+ EN   K+        +S   +  EN  LK++         
Sbjct: 725  EDLEDQSMQNVSKEIDRLKNENLDLKEKIDRLQNNRSSARLKAENEDLKQTIEELKSQMS 784

Query: 1390 XXXXRV----NDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFE---NVRQQLV 1442
                 +     +   K  +L    ++K +++ Q T E    LT+ NDE     ++ +   
Sbjct: 785  KSIDNLKSENRELRRKNSDLVEATQIKPTDVDQDTIE---QLTRENDELRRKLSLSKNDN 841

Query: 1443 EYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLN 1502
            E    IE +T  KE  + +L +KM +     E      +++R   + +L     ++  L 
Sbjct: 842  EKSNLIEQVTTLKEKNIELL-MKMRDMMEDAENGNNNDQMKR--QVSDLQ---RQNADLQ 895

Query: 1503 KQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFAS 1562
            +Q++E  + L+ E  K +     ++ + I++++ N E+      ++ S S  +K + F  
Sbjct: 896  RQLSESQRILDNERQKKSVNDDTIDQKTIKLISENREMKLEIESLKRSISDYEKLIDF-- 953

Query: 1563 DTKQGRDEQLDNTMNKELLD 1582
            + ++  D   D +    L+D
Sbjct: 954  ERQKRYDNSDDKSKISRLID 973



 Score =  110 bits (264), Expect = 4e-22
 Identities = 178/981 (18%), Positives = 430/981 (43%), Gaps = 94/981 (9%)

Query: 161  LQVKMKIMETTILDLQEKINEKDQI--IEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQM 218
            L+ ++K ++     LQ+K+NE+D+   +  K ++                   ++ KQ+ 
Sbjct: 128  LKHQIKKLQRENSHLQDKLNERDKSGDLRRKIQSLKNDMDSKETEIKQLNSTLKEIKQKF 187

Query: 219  TKMQENFIAMEAEWKDEKQRLLKDIESK-------DVRISSLEEANKLLEAARFEISL-- 269
             K +++   +  ++ + ++ ++  +++K       D+R+S L +  +  E  + +IS+  
Sbjct: 188  EKQKQDNEKLRNDYHELQETVVTSVDTKTEEIRPDDIRMSQLSQLQRENEQLQHKISILE 247

Query: 270  EHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIE 329
            + ++ + E+ Q              + +  ++ + E+   + E+  L       + K + 
Sbjct: 248  DEAQKSLEISQEDMKKTKGLEKSQQILQSQLDDANEDIKNLNEELRLANQKTQSIEKSMR 307

Query: 330  LLEHLNCQIR----QTNKELENKLATMGTESKAVSSPSKKGSPLISR-KSGRNTASKMKS 384
             L+  N +++    + + E E  ++ M  E     S  +K + L S+ +  +   +++  
Sbjct: 308  SLQRENSELKAKLDEKDAEHETTISEMKGEIAKSDSNIRKIASLNSKIEDYQEEITRIND 367

Query: 385  PWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXG 444
              +Q   E     ++    K ++ + E     L++    +++ + E++            
Sbjct: 368  ELAQTHEELRTVTSENARLKTKVGEFERRASLLSERPSKEQFTVLEEENARL-------- 419

Query: 445  KDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQ----LKQELNDEIKDVNVKD 500
              + I + QL++QQ +E         N E    I+++Q Q     K++ + E ++ ++K 
Sbjct: 420  -KSKINENQLKYQQSIETAQ----NENKELKQTISEIQNQTVQITKEKTSFEQENNDLKR 474

Query: 501  LIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVR- 559
            +  ++ S ++QI  L  + D     +   +     K    QK   +F ++ +  + + + 
Sbjct: 475  IAGEVDSLKQQIKSLKQDNDILKDKLQTAEE----KASNTQKAQSSFERLQNDYRNLKQE 530

Query: 560  LTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLL 619
            + E        +++L++E   L+  + D      +E  ++ K   ++          + +
Sbjct: 531  VNENTEKHKNSISQLKKENSQLKETIED------LEDQIHAKQNSLDREKSNNNNLRNTI 584

Query: 620  ESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELA 679
            E      ++   +L++K  E E    D+ Q   D     I S   +  ID L     EL 
Sbjct: 585  EELHSKSLENSRLLEKKKAENE----DLKQSYEDAQSKSIISSSQQRSIDRLRNENNELR 640

Query: 680  LVIENLKL---DKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELL 736
              IE+L+    +      TI+ L+ + E++  ++++    +++      +   ++I++L 
Sbjct: 641  ETIEDLQNQLGNNGSQTKTIQKLKAENEELKAEMESKQNRSLERLRNENRQLKQEIADLD 700

Query: 737  AKINHEE---QSKIQTQFGIDAKIQE-RDLYIENIESELSKYKSRICRLEESIAVMEDRR 792
            +K    +   QS ++   G+  +I++  D  ++N+  E+ + K+    L+E I  +++ R
Sbjct: 701  SKYQLSQSQLQSTVKENAGLKQEIEDLEDQSMQNVSKEIDRLKNENLDLKEKIDRLQNNR 760

Query: 793  YSLERKA--DQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKE 850
             S   KA  + L   ++E +   S+ +I   +  NR     + D V   Q+   + +   
Sbjct: 761  SSARLKAENEDLKQTIEELKSQMSK-SIDNLKSENRELRRKNSDLVEATQIKPTDVDQDT 819

Query: 851  LQKKNQILLEENQNL--QISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLK 908
            +++    L  EN  L  ++SLS      + L+E+   T L E ++ +   ++RD+  + +
Sbjct: 820  IEQ----LTRENDELRRKLSLSKNDNEKSNLIEQV--TTLKE-KNIELLMKMRDMMEDAE 872

Query: 909  RITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRD-KKVL-NEKYEKNI------EYVTQL 960
               +       Q K+++ DL+ + N  ++  + + +++L NE+ +K++      +   +L
Sbjct: 873  NGNNND-----QMKRQVSDLQRQ-NADLQRQLSESQRILDNERQKKSVNDDTIDQKTIKL 926

Query: 961  EAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTE--QYINEINKLNALL 1018
             ++ +E K  IE+L  ++ +  K    LID   QK+   S D ++  + I+E N L +++
Sbjct: 927  ISENREMKLEIESLKRSISDYEK----LIDFERQKRYDNSDDKSKISRLIDENNDLRSVI 982

Query: 1019 KQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHN 1078
            K  +   + L++K   A  S    +   E+K+     +  + +   QR S Q   ++ ++
Sbjct: 983  KDLN---LKLSEKKEFAD-SVRRRIESIEAKVGYVANEFSSYK---QRKSSQYNGNENNS 1035

Query: 1079 EELQILVREQDDQIKELKETK 1099
            EE++ L +E    +  + + K
Sbjct: 1036 EEVRYLQKENQRLVSLVSKLK 1056



 Score =  108 bits (260), Expect = 1e-21
 Identities = 197/985 (20%), Positives = 420/985 (42%), Gaps = 87/985 (8%)

Query: 390  SSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLI 449
            S+E+++   ++K  K++I KL+     L   L +++    +              K+T I
Sbjct: 115  SNESVDLQKNEKSLKHQIKKLQRENSHLQDKLNERDKS-GDLRRKIQSLKNDMDSKETEI 173

Query: 450  AQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDL-IEKLKSA 508
             QL    ++ ++         N +  N+  ++QE +   ++ + +++   D+ + +L   
Sbjct: 174  KQLNSTLKE-IKQKFEKQKQDNEKLRNDYHELQETVVTSVDTKTEEIRPDDIRMSQLSQL 232

Query: 509  EEQITQLNDEI----DAANKNMIKVKSNHKLKLKQMQKTIDNF-SKVSDSNKEIVRLTEE 563
            + +  QL  +I    D A K++ ++      K K ++K+     S++ D+N++I  L EE
Sbjct: 233  QRENEQLQHKISILEDEAQKSL-EISQEDMKKTKGLEKSQQILQSQLDDANEDIKNLNEE 291

Query: 564  LHHLSQKVAELEE-------EKGNLQLHLVDYDS----------GRMIESDV-YKKMIEM 605
            L   +QK   +E+       E   L+  L + D+          G + +SD   +K+  +
Sbjct: 292  LRLANQKTQSIEKSMRSLQRENSELKAKLDEKDAEHETTISEMKGEIAKSDSNIRKIASL 351

Query: 606  ENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADI---SQLQSDQVCSEIKSV 662
             +  E   + I+ +  +     +EL  +  +   ++ K+ +    + L S++   E  +V
Sbjct: 352  NSKIEDYQEEITRINDELAQTHEELRTVTSENARLKTKVGEFERRASLLSERPSKEQFTV 411

Query: 663  HLEEQIDALSASKKELAL----VIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENM 718
             LEE+   L +   E  L     IE  + + ++L  TI +++N    I  +  ++ QEN 
Sbjct: 412  -LEEENARLKSKINENQLKYQQSIETAQNENKELKQTISEIQNQTVQITKEKTSFEQENN 470

Query: 719  DLTDKL-EKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSR 777
            DL     E  S ++  + L + N   + K+QT     +  Q+     E ++++    K  
Sbjct: 471  DLKRIAGEVDSLKQQIKSLKQDNDILKDKLQTAEEKASNTQKAQSSFERLQNDYRNLKQE 530

Query: 778  ICRLEE----SIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDH 833
            +    E    SI+ ++     L+   + L   +  KQ +        + L N +  L  H
Sbjct: 531  VNENTEKHKNSISQLKKENSQLKETIEDLEDQIHAKQNSLDREKSNNNNLRNTIEEL--H 588

Query: 834  DRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESES 893
             + +E   L        L+KK      EN++L+ S  D Q        +    D   +E+
Sbjct: 589  SKSLENSRL--------LEKKK----AENEDLKQSYEDAQSKSIISSSQQRSIDRLRNEN 636

Query: 894  TKYQTQLRDLESNLKRITHEHQTLIVQK-KKEIEDLEIEFNTQIESAIRDKKVLNEKYEK 952
             + +  + DL++ L    +  QT  +QK K E E+L+ E  ++   ++   +  N + ++
Sbjct: 637  NELRETIEDLQNQLG--NNGSQTKTIQKLKAENEELKAEMESKQNRSLERLRNENRQLKQ 694

Query: 953  NI---EYVTQL-EAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYI 1008
             I   +   QL ++QLQ        L   +E+L   +++ + K + + + ++ D  E+  
Sbjct: 695  EIADLDSKYQLSQSQLQSTVKENAGLKQEIEDLEDQSMQNVSKEIDRLKNENLDLKEKID 754

Query: 1009 N-EINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRV 1067
              + N+ +A LK ++E+   L Q I   +      + + +S+  +   K  ++ E     
Sbjct: 755  RLQNNRSSARLKAENED---LKQTIEELKSQMSKSIDNLKSENRELRRKNSDLVE----- 806

Query: 1068 SKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANN 1127
            + Q+  +    + ++ L RE D    EL+  KL+   N  +   +I   T    +    N
Sbjct: 807  ATQIKPTDVDQDTIEQLTREND----ELRR-KLSLSKNDNEKSNLIEQVT----TLKEKN 857

Query: 1128 VDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTG 1187
            ++                  ++  ++ S LQ Q+A L  +L E   +I+  E    +   
Sbjct: 858  IELLMKMRDMMEDAENGNNNDQMKRQVSDLQRQNADLQRQLSES-QRILDNER-QKKSVN 915

Query: 1188 HDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWK-QHLAQR 1246
             D ++Q+ I +L S+  ++  E ++L  ++++    I     +R     +  K   L   
Sbjct: 916  DDTIDQKTI-KLISENREMKLEIESLKRSISDYEKLIDFERQKRYDNSDDKSKISRLIDE 974

Query: 1247 EADFQKTEHELRVQLS---AFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQ-NKLQDK 1302
              D +    +L ++LS    F     + ++S+++      N+  + +Q  S Q N  ++ 
Sbjct: 975  NNDLRSVIKDLNLKLSEKKEFADSVRRRIESIEAKVGYVANEFSSYKQRKSSQYNGNENN 1034

Query: 1303 EEHLRNLQEKYADVINQIEILRSEI 1327
             E +R LQ++   +++ +  L+ EI
Sbjct: 1035 SEEVRYLQKENQRLVSLVSKLKCEI 1059



 Score = 92.7 bits (220), Expect = 8e-17
 Identities = 186/922 (20%), Positives = 381/922 (41%), Gaps = 63/922 (6%)

Query: 215  KQQMTKMQ-EN-FIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHS 272
            K Q+ K+Q EN  +  +   +D+   L + I+S    + S E   K L +   EI  +  
Sbjct: 129  KHQIKKLQRENSHLQDKLNERDKSGDLRRKIQSLKNDMDSKETEIKQLNSTLKEIKQKFE 188

Query: 273  KLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLE 332
            K  Q+ E+                ++++  S + KTE      + ++ +++L ++ E L+
Sbjct: 189  KQKQDNEKLRNDYHEL--------QETVVTSVDTKTEEIRPDDIRMSQLSQLQRENEQLQ 240

Query: 333  HLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSE 392
            H   +I     E +  L     + K      K    L S+    N   K  +   +L+++
Sbjct: 241  H---KISILEDEAQKSLEISQEDMKKTKGLEKSQQILQSQLDDANEDIKNLNEELRLANQ 297

Query: 393  TLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQL 452
               Q  +K +   +    E+  +   KD  + E  ISE                  IA L
Sbjct: 298  K-TQSIEKSMRSLQRENSELKAKLDEKD-AEHETTISE----MKGEIAKSDSNIRKIASL 351

Query: 453  QLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQI 512
              + + + E   +  +       +E  +        L  ++ +   +  +   + ++EQ 
Sbjct: 352  NSKIEDYQE--EITRINDELAQTHEELRTVTSENARLKTKVGEFERRASLLSERPSKEQF 409

Query: 513  TQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSK-----VSDSNKEIVRLTEELHHL 567
            T L +E +A  K+ I   + ++LK +Q  +T  N +K     +S+   + V++T+E    
Sbjct: 410  TVLEEE-NARLKSKI---NENQLKYQQSIETAQNENKELKQTISEIQNQTVQITKEKTSF 465

Query: 568  SQKVAELEEEKGNLQLHLVDYDSGRMIESDVYK-KMIEMENLAETRLKAISLLESQKFDL 626
             Q+  +L+   G +   L         ++D+ K K+   E  A    KA S  E  + D 
Sbjct: 466  EQENNDLKRIAGEVD-SLKQQIKSLKQDNDILKDKLQTAEEKASNTQKAQSSFERLQNDY 524

Query: 627  VQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSV--HLEEQIDALSASKKELALVIEN 684
                ++ Q+  +  E     ISQL+ +   S++K     LE+QI A   S         N
Sbjct: 525  ---RNLKQEVNENTEKHKNSISQLKKEN--SQLKETIEDLEDQIHAKQNSLDREKSNNNN 579

Query: 685  LKLDKEQLYGTIKDLENDKEDIMNKLQN--YIQENMDLTDK-LEKMSAEKISELLAKINH 741
            L+   E+L+   K LEN +     K +N    Q   D   K +   S ++  + L   N+
Sbjct: 580  LRNTIEELHS--KSLENSRLLEKKKAENEDLKQSYEDAQSKSIISSSQQRSIDRLRNENN 637

Query: 742  EEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRI-CRLEESIAVMEDRRYSLERKAD 800
            E +  I+           +   I+ +++E  + K+ +  +   S+  + +    L+++  
Sbjct: 638  ELRETIEDLQNQLGNNGSQTKTIQKLKAENEELKAEMESKQNRSLERLRNENRQLKQEIA 697

Query: 801  QLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHD-RVVEKQLLEIEHENKELQKKNQILL 859
             L S  Q  Q        +   L   +  L D   + V K++  +++EN +L++K   L 
Sbjct: 698  DLDSKYQLSQSQLQSTVKENAGLKQEIEDLEDQSMQNVSKEIDRLKNENLDLKEKIDRLQ 757

Query: 860  EENQN--LQISLSDMQQHYNALVEKANRT-DLAESESTKYQTQLRDL-ESNLKRITHEHQ 915
                +  L+    D++Q    L  + +++ D  +SE+ + + +  DL E+   + T   Q
Sbjct: 758  NNRSSARLKAENEDLKQTIEELKSQMSKSIDNLKSENRELRRKNSDLVEATQIKPTDVDQ 817

Query: 916  TLIVQKKKEIEDLEIEFNTQIESAIRDKKV--LNEKYEKNIEYVTQLEAQLQ--EYKNNI 971
              I Q  +E ++L  + +       +   +  +    EKNIE + ++   ++  E  NN 
Sbjct: 818  DTIEQLTRENDELRRKLSLSKNDNEKSNLIEQVTTLKEKNIELLMKMRDMMEDAENGNNN 877

Query: 972  ENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQK 1031
            + +   V +L + N +L     Q+Q ++S    +    + +  +  + QK  ++I+ N++
Sbjct: 878  DQMKRQVSDLQRQNADL-----QRQLSESQRILDNERQKKSVNDDTIDQKTIKLISENRE 932

Query: 1032 INNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQ 1091
            +     S    +SDYE  +     K  +  ++  ++S+ L+D    N +L+ ++++ + +
Sbjct: 933  MKLEIESLKRSISDYEKLIDFERQKRYDNSDDKSKISR-LID---ENNDLRSVIKDLNLK 988

Query: 1092 IKELKETKLTFEMNIPKTEGMI 1113
            + E KE   +    I   E  +
Sbjct: 989  LSEKKEFADSVRRRIESIEAKV 1010



 Score = 72.9 bits (171), Expect = 7e-11
 Identities = 121/617 (19%), Positives = 270/617 (43%), Gaps = 58/617 (9%)

Query: 212  EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271
            E+      K Q +F  ++ ++++ KQ + ++ E     IS L++ N  L+    ++  + 
Sbjct: 504  EEKASNTQKAQSSFERLQNDYRNLKQEVNENTEKHKNSISQLKKENSQLKETIEDLEDQI 563

Query: 272  SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSC---EEKTEIEE-KGSLEIANMTELT-- 325
                  L++              L  +S+E S    ++K E E+ K S E A    +   
Sbjct: 564  HAKQNSLDREKSNNNNLRNTIEELHSKSLENSRLLEKKKAENEDLKQSYEDAQSKSIISS 623

Query: 326  ---KKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTAS-- 380
               + I+ L + N ++R+T ++L+N+L   G+++K +     +   L +    +   S  
Sbjct: 624  SQQRSIDRLRNENNELRETIEDLQNQLGNNGSQTKTIQKLKAENEELKAEMESKQNRSLE 683

Query: 381  KMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXX 440
            ++++   QL  E  + D+  +++++++         L +++ D E    ++         
Sbjct: 684  RLRNENRQLKQEIADLDSKYQLSQSQLQSTVKENAGLKQEIEDLE----DQSMQNVSKEI 739

Query: 441  XXXGKDTLIAQLQLEHQQHMEGPSLIHV------GTNTEDVNEIAKVQEQLKQELNDEIK 494
                 + L  + +++  Q+    + +         T  E  ++++K  + LK E N E++
Sbjct: 740  DRLKNENLDLKEKIDRLQNNRSSARLKAENEDLKQTIEELKSQMSKSIDNLKSE-NRELR 798

Query: 495  DVNVKDLIE--KLKSAE------EQITQLNDEIDAANKNMIKVKSNHKLKLKQM-----Q 541
              N  DL+E  ++K  +      EQ+T+ NDE+    K  +    N K  L +      +
Sbjct: 799  RKN-SDLVEATQIKPTDVDQDTIEQLTRENDEL--RRKLSLSKNDNEKSNLIEQVTTLKE 855

Query: 542  KTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKK 601
            K I+   K+ D  ++          + ++V++L+ +  +LQ  L   +S R+++++  KK
Sbjct: 856  KNIELLMKMRDMMEDAENGNNN-DQMKRQVSDLQRQNADLQRQL--SESQRILDNERQKK 912

Query: 602  MIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADIS-QLQSDQVCSEIK 660
             +  + + +  +K IS  E+++  L  E+  L++   + E KL D   Q + D    + K
Sbjct: 913  SVNDDTIDQKTIKLIS--ENREMKL--EIESLKRSISDYE-KLIDFERQKRYDNSDDKSK 967

Query: 661  SVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDL 720
               L ++ + L +  K+L L +   K   + +   I+ +E     + N+  +Y Q     
Sbjct: 968  ISRLIDENNDLRSVIKDLNLKLSEKKEFADSVRRRIESIEAKVGYVANEFSSYKQRKSSQ 1027

Query: 721  TDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRIC- 779
             +  E  ++E++  L        Q + Q    + +K++   + I NI ++    K  +  
Sbjct: 1028 YNGNEN-NSEEVRYL--------QKENQRLVSLVSKLKCEIIGIRNIAAQQISSKKSLSP 1078

Query: 780  -RLEESIAVMEDRRYSL 795
              ++E I   E+ RY++
Sbjct: 1079 EEIKEIIRAFEELRYAV 1095


>UniRef50_A0DR44 Cluster: Chromosome undetermined scaffold_6, whole
            genome shotgun sequence; n=3; Paramecium tetraurelia|Rep:
            Chromosome undetermined scaffold_6, whole genome shotgun
            sequence - Paramecium tetraurelia
          Length = 1947

 Score =  127 bits (306), Expect = 3e-27
 Identities = 217/1148 (18%), Positives = 479/1148 (41%), Gaps = 100/1148 (8%)

Query: 483  EQLKQELN-DEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANK----NMIKVKS-NHKLK 536
            ++LK+E+   E+K ++   +  + +    + +++ DE    NK    N++  ++ N+K K
Sbjct: 504  QKLKKEVQLSEVKFIDQTKITHQFEKEVNEKSRIIDEYKKKNKELQENLVSAQTENNKYK 563

Query: 537  LKQMQ-KTID------NFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYD 589
            ++ ++ K ++      N  K +   +E+ R+ +E   L +K+AELE +         D +
Sbjct: 564  IQLLEVKALEGGSANGNGQKSNSYQREVERIQDENARLQKKIAELENQVLEQNSKSSDQN 623

Query: 590  SGRMIESDV----YKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLA 645
              R ++  +      K +    L++ R   I+ L+ Q   L+ E + ++ + D+V  +  
Sbjct: 624  ESRKLQIQITQLEQSKFLINAQLSQ-REATITQLQRQIQGLLDE-NNMKSEGDQVIQERR 681

Query: 646  DISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKED 705
              ++LQ      +      + ++  +    KE  L+ + LK        +I   +++ + 
Sbjct: 682  KNAELQLQLSNYQTSEKVWKSKLSDIEHKLKEQTLINQELKTKVNSSNPSITITKDENDR 741

Query: 706  IMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIE 765
               +++  +   ++    L K   + I EL  K+N E       Q   D  +++ +    
Sbjct: 742  NYERIREQLSLELEAKTSLTKQLFQSIDELTIKLNQERSKSQNLQIEYDQLLEQTNF--- 798

Query: 766  NIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVN 825
                          R   S  + +  +   +R  D   + +++ Q   S+   Q+ +L +
Sbjct: 799  --------------RQNRSQTIQQQNQQKDQRIQD-FQAQIEQLQLELSKAKSQQSQLAS 843

Query: 826  RLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANR 885
                L ++ +  E +++E+EH+ +   +  Q  +E+  + +  + ++    N L E+   
Sbjct: 844  MHQNLQENFKAAEMKIVELEHQKRMYDRTIQEKVEQVTSHETKIKELNTQKNQLDEQLTE 903

Query: 886  TDLAES------ESTKYQTQLRDLE-SNLKRITHEHQTLIVQKKKEI----EDLEIEFNT 934
            +   +S      ES ++Q   +  E  NLK+   E + +I+ + ++I    E  E E N 
Sbjct: 904  SLKKQSEQRVLLESLQFQVGNKGKEYENLKKKIEEQELIILGQNEKIHKVKESNEAEQNE 963

Query: 935  QIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQ 994
            +       + +  + Y K  E +   + Q+    + I NLN  V  L +    L +K V+
Sbjct: 964  KSILGTEQENLKKQLYMKE-EQIRSRQEQINSLNDQIRNLNEKVSSLEQQR-TLQNKQVK 1021

Query: 995  KQQTQSPDYTEQYINEINKLNA---LLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLA 1051
              + Q      +Y+ E +K+++   L KQ+  E  A   K+  +   Y + +S+   +L 
Sbjct: 1022 HLEDQINSREREYMTEHSKVSSERDLQKQRVIEAEAQILKLQQSDKKYKTEISNLNEELQ 1081

Query: 1052 QFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEG 1111
            Q    LE++ ++++    Q   S++ N E     + Q  ++++L++      + I + + 
Sbjct: 1082 QQLLTLEHLNKQIKDYEIQQNQSRESNLENS---KVQSIRLEKLEQQNQNMNIKI-EAQS 1137

Query: 1112 MIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQEC 1171
              I      + +    +              KVQEEE     R   ++Q      ++ + 
Sbjct: 1138 QEIKQYTAKIEEQLTTI---------TELKYKVQEEESL---RKAKEKQVNDKTQQIGQL 1185

Query: 1172 YTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQR 1231
              ++I+++    +        Q Q + LK K +       +L S   E  +S+ S   ++
Sbjct: 1186 ENQLIKIQEKYNQSNRSSQDIQNQYDDLKKKFDVELNNMQSLQSRSIEY-NSLQSRYMEQ 1244

Query: 1232 GFEIAELWKQHLAQREA--DFQKTEHELRVQLSAFESK------YEQLLDSVQSSTQEET 1283
            G +++ L KQ L   E    +QK + EL+      +SK      +E  +  + +  +E  
Sbjct: 1245 GQKLSSLEKQLLDYNEISDQYQKQKKELQSLTDLLDSKLATIVSHETKIIDLTNQLKESN 1304

Query: 1284 NKI--VTMEQVTSLQNKLQDKE--EHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXX 1339
            +++  V  E    +Q + QD +    L+ ++ +  D+  Q+    + I++++ A      
Sbjct: 1305 SQLQQVRKENHEIMQKRAQDMQAMAQLKQIEVENGDLKQQVYSHEATIQNQE-ALLSVLK 1363

Query: 1340 XXXXXXXXXXXDLRTENQSYKQMQEQSILNINEE-----NAQLKKSSXXXXXXXXXXXXR 1394
                        L+ + Q   +   + +++++E+     N Q K  S            R
Sbjct: 1364 GNQLNLEQSQMKLKIDYQHLDEKYNEKLIDLDEKSKTLFNLQNKFDSLSFRAQQSEENLR 1423

Query: 1395 VNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYE 1454
            + + +    +  ++L L++ +IY K  +  I L   N + E +++Q+   +K+ + L  E
Sbjct: 1424 LVEDQRDDYQSRYELALQELDIY-KGKDKEINLMAAN-KIE-LQEQMHSVQKKNKVLERE 1480

Query: 1455 KESELAILRLKMHENANHYETMQ-KESEIERVK-LIEELNVKITESVS----LNKQVAEL 1508
             +     L+ K  +      T+Q KE +I  ++  I +L   +T S +    L  ++ E+
Sbjct: 1481 LQVSQNALQSKESDILQLQHTIQKKEQQITTLEGTIVKLKADLTNSKNSYEQLQLELTEM 1540

Query: 1509 NK---ALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTK 1565
            N    +  E  ++  ++     N+  +I  L  +I  LQ+  R    +  K  S A    
Sbjct: 1541 NSEQTSSGELFSQVKKLTNDNLNKNTQIDQLKLQINELQDKNRNLEKQYNKLRSDALVGN 1600

Query: 1566 QGRDEQLD 1573
            QG  E  +
Sbjct: 1601 QGNSESFE 1608



 Score =  124 bits (299), Expect = 2e-26
 Identities = 232/1176 (19%), Positives = 511/1176 (43%), Gaps = 86/1176 (7%)

Query: 456  HQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKL---KSAEEQI 512
            + Q   GP L    T      +   +Q  LKQ  ++++   N++     L   +  +E +
Sbjct: 402  NSQLNNGPELNRKKTVQMKQKDQTNIQGDLKQVEDEDLVFSNLRRKTMHLLNQEEVDEDV 461

Query: 513  TQLNDEIDAANKNMI---KVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQ 569
              L D I+   + +I   +V  +  LK+ +MQ+  +   +     K+ V+L+E       
Sbjct: 462  AVLTDYINKLEEVLILKHRVVKDQNLKILEMQEKNEKIFEEIQKLKKEVQLSEVKFIDQT 521

Query: 570  KVAELEEEKGNLQLHLVD--YDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFD-L 626
            K+    E++ N +  ++D      + ++ ++     E  N  + +L  +  LE    +  
Sbjct: 522  KITHQFEKEVNEKSRIIDEYKKKNKELQENLVSAQTE-NNKYKIQLLEVKALEGGSANGN 580

Query: 627  VQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASK-KELALVIENL 685
             Q+ +  Q++ + ++D+ A   +LQ  +  +E+++  LE+   +   ++ ++L + I  L
Sbjct: 581  GQKSNSYQREVERIQDENA---RLQ--KKIAELENQVLEQNSKSSDQNESRKLQIQITQL 635

Query: 686  KLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAE--KISELLAKI-NHE 742
            +  K  +   +   E     +  ++Q  + EN ++  + +++  E  K +EL  ++ N++
Sbjct: 636  EQSKFLINAQLSQREATITQLQRQIQGLLDEN-NMKSEGDQVIQERRKNAELQLQLSNYQ 694

Query: 743  EQSKI--QTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKAD 800
               K+       I+ K++E+ L  + ++++++     I   ++      DR Y  ER  +
Sbjct: 695  TSEKVWKSKLSDIEHKLKEQTLINQELKTKVNSSNPSITITKDE----NDRNY--ERIRE 748

Query: 801  QLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLE 860
            QL   L+ K     +     DEL  +L       + ++ +  ++  +    Q ++Q + +
Sbjct: 749  QLSLELEAKTSLTKQLFQSIDELTIKLNQERSKSQNLQIEYDQLLEQTNFRQNRSQTIQQ 808

Query: 861  ENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQ 920
            +NQ     + D Q     L  + ++   A+S+ ++  +  ++L+ N K    E + + ++
Sbjct: 809  QNQQKDQRIQDFQAQIEQLQLELSK---AKSQQSQLASMHQNLQENFK--AAEMKIVELE 863

Query: 921  KKKEIEDLEIEFNT-QIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVE 979
             +K + D  I+    Q+ S     K LN +  +  E +T+   +  E +  +E+L   V 
Sbjct: 864  HQKRMYDRTIQEKVEQVTSHETKIKELNTQKNQLDEQLTESLKKQSEQRVLLESLQFQVG 923

Query: 980  ELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSY 1039
               K   E + K +++Q+       E+ I+++ + N   +Q ++ I+   Q+ N  +  Y
Sbjct: 924  NKGK-EYENLKKKIEEQELIILGQNEK-IHKVKESNE-AEQNEKSILGTEQE-NLKKQLY 979

Query: 1040 M--SMVSDYESKLAQFTTKLENMEEEMQRVSKQ-LLDSKQ--HNEELQILVREQDDQIKE 1094
            M    +   + ++     ++ N+ E++  + +Q  L +KQ  H E+ QI  RE++     
Sbjct: 980  MKEEQIRSRQEQINSLNDQIRNLNEKVSSLEQQRTLQNKQVKHLED-QINSREREYM--- 1035

Query: 1095 LKETKLTFEMNIPKTEGMIISSTIEPM--SDDANNVDXXXXXXXXXXXXLKVQEEEEFIQ 1152
             + +K++ E ++ K   +   + I  +  SD     +            L ++   + I+
Sbjct: 1036 TEHSKVSSERDLQKQRVIEAEAQILKLQQSDKKYKTEISNLNEELQQQLLTLEHLNKQIK 1095

Query: 1153 ERSVLQEQSAKLNTELQECYT-KIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTEND 1211
            +  + Q QS + N E  +  + ++ +LE  N  +        ++I Q  +K+E+  T   
Sbjct: 1096 DYEIQQNQSRESNLENSKVQSIRLEKLEQQNQNMNIKIEAQSQEIKQYTAKIEEQLTTIT 1155

Query: 1212 NLLSTVAE---LRSSISSAVDQRGFEIAELWKQHLAQREADFQ--KTEHELRVQLSAFES 1266
             L   V E   LR +    V+ +  +I +L  Q +  +E   Q  ++  +++ Q    + 
Sbjct: 1156 ELKYKVQEEESLRKAKEKQVNDKTQQIGQLENQLIKIQEKYNQSNRSSQDIQNQYDDLKK 1215

Query: 1267 KYEQLLDSVQS--STQEETNKIVT--MEQ---VTSLQNKLQDKEEHLRNLQEKYADVINQ 1319
            K++  L+++QS  S   E N + +  MEQ   ++SL+ +L D  E     Q++  ++ + 
Sbjct: 1216 KFDVELNNMQSLQSRSIEYNSLQSRYMEQGQKLSSLEKQLLDYNEISDQYQKQKKELQSL 1275

Query: 1320 IEILRSEIED--EKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQ------SILNIN 1371
             ++L S++                          +R EN    Q + Q       +  I 
Sbjct: 1276 TDLLDSKLATIVSHETKIIDLTNQLKESNSQLQQVRKENHEIMQKRAQDMQAMAQLKQIE 1335

Query: 1372 EENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTH-QLELK--DSEIYQKTHEYTITLT 1428
             EN  LK+               ++  +   L L   Q++LK     + +K +E  I L 
Sbjct: 1336 VENGDLKQQVYSHEATIQNQEALLSVLKGNQLNLEQSQMKLKIDYQHLDEKYNEKLIDLD 1395

Query: 1429 QRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLI 1488
            +++    N++ +      R +    + E  L ++  +  +  + YE   +E +I + K  
Sbjct: 1396 EKSKTLFNLQNKFDSLSFRAQ----QSEENLRLVEDQRDDYQSRYELALQELDIYKGK-D 1450

Query: 1489 EELNVKITESVSLNKQ---VAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQN 1545
            +E+N+     + L +Q   V + NK LE E+  +   Q AL+++E +I+ L   I   + 
Sbjct: 1451 KEINLMAANKIELQEQMHSVQKKNKVLERELQVS---QNALQSKESDILQLQHTIQKKEQ 1507

Query: 1546 MVRASSSKIQKHVSFASDTKQGRDE-QLDNT-MNKE 1579
             +      I K  +  +++K   ++ QL+ T MN E
Sbjct: 1508 QITTLEGTIVKLKADLTNSKNSYEQLQLELTEMNSE 1543



 Score =  116 bits (280), Expect = 4e-24
 Identities = 235/1231 (19%), Positives = 534/1231 (43%), Gaps = 85/1231 (6%)

Query: 154  KDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXED 213
            KD  L +L+++ K     I +  +K+ ++ Q+ E K    T                 ++
Sbjct: 483  KDQNLKILEMQEK--NEKIFEEIQKLKKEVQLSEVKFIDQTKITHQFEKEVNEKSRIIDE 540

Query: 214  TKQQMTKMQENFIAMEAEWKDEKQRLL--KDIESKDVRISSLEEANKLLEAARFEI-SLE 270
             K++  ++QEN ++ + E    K +LL  K +E      +  +  +   E  R +  +  
Sbjct: 541  YKKKNKELQENLVSAQTENNKYKIQLLEVKALEGGSANGNGQKSNSYQREVERIQDENAR 600

Query: 271  HSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTE--IEEKGSLEIANMTELTKKI 328
              K   ELE                 K  I+ +  E+++  I  + S   A +T+L ++I
Sbjct: 601  LQKKIAELENQVLEQNSKSSDQNESRKLQIQITQLEQSKFLINAQLSQREATITQLQRQI 660

Query: 329  E-LLEHLNC--------QIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTA 379
            + LL+  N         Q R+ N EL+ +L+   T  K   S        +  ++  N  
Sbjct: 661  QGLLDENNMKSEGDQVIQERRKNAELQLQLSNYQTSEKVWKSKLSDIEHKLKEQTLINQE 720

Query: 380  SKMKSPWSQLSSETLNQDTDKKINK-NEIAKLEMVIQ-SLNKDLVDKEYVISEK-DTXXX 436
             K K   S  S      + D+   +  E   LE+  + SL K L      ++ K +    
Sbjct: 721  LKTKVNSSNPSITITKDENDRNYERIREQLSLELEAKTSLTKQLFQSIDELTIKLNQERS 780

Query: 437  XXXXXXXGKDTLIAQLQL-EHQQHMEGPSLIHVGTNTEDVN-EIAKVQEQLKQELNDEIK 494
                     D L+ Q    +++               +D   +I ++Q +L +  + + +
Sbjct: 781  KSQNLQIEYDQLLEQTNFRQNRSQTIQQQNQQKDQRIQDFQAQIEQLQLELSKAKSQQSQ 840

Query: 495  DVNV-KDLIEKLKSAEEQITQLNDE---IDAANKNMIKVKSNHKLKLKQMQKTIDNFSK- 549
              ++ ++L E  K+AE +I +L  +    D   +  ++  ++H+ K+K++    +   + 
Sbjct: 841  LASMHQNLQENFKAAEMKIVELEHQKRMYDRTIQEKVEQVTSHETKIKELNTQKNQLDEQ 900

Query: 550  VSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLA 609
            +++S K+       L  L  +V    +E  NL+  + + +   + +++   K+ E  N A
Sbjct: 901  LTESLKKQSEQRVLLESLQFQVGNKGKEYENLKKKIEEQELIILGQNEKIHKVKE-SNEA 959

Query: 610  ETRLKAI-----SLLESQKFDLVQELHILQQKYDEVEDKLAD----ISQLQSDQVCSEIK 660
            E   K+I       L+ Q +   +++   Q++ + + D++ +    +S L+  +     +
Sbjct: 960  EQNEKSILGTEQENLKKQLYMKEEQIRSRQEQINSLNDQIRNLNEKVSSLEQQRTLQNKQ 1019

Query: 661  SVHLEEQIDALSAS-KKELALVIENLKLDKEQLYGT----IKDLENDKE---DIMNKLQN 712
              HLE+QI++       E + V     L K+++       +K  ++DK+   +I N  + 
Sbjct: 1020 VKHLEDQINSREREYMTEHSKVSSERDLQKQRVIEAEAQILKLQQSDKKYKTEISNLNEE 1079

Query: 713  YIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELS 772
              Q+ + L    +++   +I +  ++ ++ E SK+Q+      + Q +++ I+ IE++  
Sbjct: 1080 LQQQLLTLEHLNKQIKDYEIQQNQSRESNLENSKVQSIRLEKLEQQNQNMNIK-IEAQSQ 1138

Query: 773  KYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMD 832
            + K    ++EE +  + + +Y ++ +     S  + K+K  ++ T Q  +L N+L  + +
Sbjct: 1139 EIKQYTAKIEEQLTTITELKYKVQEEE----SLRKAKEKQVNDKTQQIGQLENQLIKIQE 1194

Query: 833  HDRVVEKQLLEIEHENKELQKKNQILLEENQNLQ---ISLSDMQQHYNALVEKANRTD-- 887
                  +   +I+++  +L+KK  + L   Q+LQ   I  + +Q  Y    +K +  +  
Sbjct: 1195 KYNQSNRSSQDIQNQYDDLKKKFDVELNNMQSLQSRSIEYNSLQSRYMEQGQKLSSLEKQ 1254

Query: 888  -LAESE-STKYQTQLRDLESNLKRITHEHQTLIVQKKKEIE--DLEIEFNTQIESAIRDK 943
             L  +E S +YQ Q ++L+S    +  +  T++  + K I+  +   E N+Q++   ++ 
Sbjct: 1255 LLDYNEISDQYQKQKKELQSLTDLLDSKLATIVSHETKIIDLTNQLKESNSQLQQVRKEN 1314

Query: 944  KVLNEKYEKNIEYVTQL---EAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQS 1000
              + +K  ++++ + QL   E +  + K  + +    ++    +   L    +  +Q+Q 
Sbjct: 1315 HEIMQKRAQDMQAMAQLKQIEVENGDLKQQVYSHEATIQNQEALLSVLKGNQLNLEQSQM 1374

Query: 1001 P---DYTEQYINE-INKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTK 1056
                DY  Q+++E  N+    L +K + +  L  K ++  +S+ +  S+   +L +   +
Sbjct: 1375 KLKIDY--QHLDEKYNEKLIDLDEKSKTLFNLQNKFDS--LSFRAQQSEENLRLVE--DQ 1428

Query: 1057 LENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISS 1116
             ++ +   +   ++L   K  ++E+ ++   + +  +++   +   +  + + E  +  +
Sbjct: 1429 RDDYQSRYELALQELDIYKGKDKEINLMAANKIELQEQMHSVQK--KNKVLERELQVSQN 1486

Query: 1117 TIEPMSDDANNVDXXXXXXXXXXXXLK---VQEEEEFIQERSVLQEQSAKLNTELQECYT 1173
             ++    D   +             L+   V+ + +    ++  ++   +L TE+    T
Sbjct: 1487 ALQSKESDILQLQHTIQKKEQQITTLEGTIVKLKADLTNSKNSYEQLQLEL-TEMNSEQT 1545

Query: 1174 KIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGF 1233
               +L +   +LT  ++    QI+QLK ++ +L  +N NL     +LRS  +   +Q   
Sbjct: 1546 SSGELFSQVKKLTNDNLNKNTQIDQLKLQINELQDKNRNLEKQYNKLRSD-ALVGNQGNS 1604

Query: 1234 EIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLD--SVQS--STQEETNKIVTM 1289
            E  EL +  + + E  F+++++ +R Q      + +QLLD  S QS  S Q E  +    
Sbjct: 1605 ESFEL-RSRVDELEGQFKQSQNSIR-QKDQQIQELKQLLDNQSYQSNQSNQREKEREREK 1662

Query: 1290 EQVTSLQNK-LQDKEEHLRNLQEKYADVINQ 1319
            E+     NK + +  +H     ++Y  +I Q
Sbjct: 1663 EKEKQTYNKPINNSNDHENMKIQEYQFIIEQ 1693



 Score =  110 bits (265), Expect = 3e-22
 Identities = 223/1221 (18%), Positives = 523/1221 (42%), Gaps = 110/1221 (9%)

Query: 305  EEKTEIEEKGSLEIANMT-ELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPS 363
            +++ ++ E   ++   +T +  K++     +  + ++ NKEL+  L +  TE+       
Sbjct: 507  KKEVQLSEVKFIDQTKITHQFEKEVNEKSRIIDEYKKKNKELQENLVSAQTENNKYKIQL 566

Query: 364  KKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVD 423
             +   L   + G    +  KS   Q   E + QD + ++ K +IA+LE  +   N    D
Sbjct: 567  LEVKAL---EGGSANGNGQKSNSYQREVERI-QDENARLQK-KIAELENQVLEQNSKSSD 621

Query: 424  K------EYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNT-EDVN 476
            +      +  I++ +            ++  I QLQ + Q  ++  ++   G    ++  
Sbjct: 622  QNESRKLQIQITQLEQSKFLINAQLSQREATITQLQRQIQGLLDENNMKSEGDQVIQERR 681

Query: 477  EIAKVQEQLKQ-ELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKL 535
            + A++Q QL   + ++++    + D+  KLK       +L  +++++N ++   K  +  
Sbjct: 682  KNAELQLQLSNYQTSEKVWKSKLSDIEHKLKEQTLINQELKTKVNSSNPSITITKDENDR 741

Query: 536  KLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLH---LVDYDSGR 592
              +++++ +    +   S  +  +L + +  L+ K+ +   +  NLQ+    L++  + R
Sbjct: 742  NYERIREQLSLELEAKTSLTK--QLFQSIDELTIKLNQERSKSQNLQIEYDQLLEQTNFR 799

Query: 593  MIESDVYKKMIEMENLAETRLKA--------ISLLESQKFDLVQELHILQQKYDEVEDKL 644
               S   ++  + ++      +A        +S  +SQ+  L      LQ+ +   E K+
Sbjct: 800  QNRSQTIQQQNQQKDQRIQDFQAQIEQLQLELSKAKSQQSQLASMHQNLQENFKAAEMKI 859

Query: 645  ADISQLQS--DQVCSE-IKSVHLEE-QIDALSASKKEL-ALVIENLKLDKEQ--LYGTIK 697
             ++   +   D+   E ++ V   E +I  L+  K +L   + E+LK   EQ  L  +++
Sbjct: 860  VELEHQKRMYDRTIQEKVEQVTSHETKIKELNTQKNQLDEQLTESLKKQSEQRVLLESLQ 919

Query: 698  DLENDKEDIMNKLQNYIQEN----MDLTDKLEKMSAEKISELLAK-INHEEQSKIQTQFG 752
                +K      L+  I+E     +   +K+ K+     +E   K I   EQ  ++ Q  
Sbjct: 920  FQVGNKGKEYENLKKKIEEQELIILGQNEKIHKVKESNEAEQNEKSILGTEQENLKKQLY 979

Query: 753  I-DAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGS----YLQ 807
            + + +I+ R   I ++  ++     ++  LE+   +   +   LE   DQ+ S    Y+ 
Sbjct: 980  MKEEQIRSRQEQINSLNDQIRNLNEKVSSLEQQRTLQNKQVKHLE---DQINSREREYMT 1036

Query: 808  EKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQI 867
            E  K  SE  +Q+  ++   A ++   +  +K   EI + N+ELQ+  Q+L  E+ N QI
Sbjct: 1037 EHSKVSSERDLQKQRVIEAEAQILKLQQSDKKYKTEISNLNEELQQ--QLLTLEHLNKQI 1094

Query: 868  SLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIED 927
               ++QQ+ +      N + +      K + Q +++   ++  + E +    + ++++  
Sbjct: 1095 KDYEIQQNQSRESNLEN-SKVQSIRLEKLEQQNQNMNIKIEAQSQEIKQYTAKIEEQLTT 1153

Query: 928  L-EIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNL 986
            + E+++  Q E ++R  K   ++     + + QLE QL + +      N + +++     
Sbjct: 1154 ITELKYKVQEEESLRKAK--EKQVNDKTQQIGQLENQLIKIQEKYNQSNRSSQDIQNQYD 1211

Query: 987  ELIDK------HVQKQQTQSPDYTE---QYINEINKLNALLKQKDE--EIIALNQK---- 1031
            +L  K      ++Q  Q++S +Y     +Y+ +  KL++L KQ  +  EI    QK    
Sbjct: 1212 DLKKKFDVELNNMQSLQSRSIEYNSLQSRYMEQGQKLSSLEKQLLDYNEISDQYQKQKKE 1271

Query: 1032 ---INNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHN-EELQILVRE 1087
               + +   S ++ +  +E+K+   T +L+    ++Q+V K+  +  Q   +++Q + + 
Sbjct: 1272 LQSLTDLLDSKLATIVSHETKIIDLTNQLKESNSQLQQVRKENHEIMQKRAQDMQAMAQL 1331

Query: 1088 QDDQIK--ELKETKLTFEMNIPKTEGMI---------ISSTIEPMSDDANNVDXXXXXXX 1136
            +  +++  +LK+   + E  I   E ++         +  +   +  D  ++D       
Sbjct: 1332 KQIEVENGDLKQQVYSHEATIQNQEALLSVLKGNQLNLEQSQMKLKIDYQHLDEKYNEKL 1391

Query: 1137 X-----XXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTEL-TGHDV 1190
                        +Q + + +  R+   E++ +L  + ++ Y    +L     ++  G D 
Sbjct: 1392 IDLDEKSKTLFNLQNKFDSLSFRAQQSEENLRLVEDQRDDYQSRYELALQELDIYKGKDK 1451

Query: 1191 -VNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREAD 1249
             +N    N+++ + EQ+++          EL+ S  +A+  +  +I +L  QH  Q++  
Sbjct: 1452 EINLMAANKIELQ-EQMHSVQKKNKVLERELQVS-QNALQSKESDILQL--QHTIQKKEQ 1507

Query: 1250 ----FQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEH 1305
                 + T  +L+  L+  ++ YEQL   +     E+T+      QV  L N   +K   
Sbjct: 1508 QITTLEGTIVKLKADLTNSKNSYEQLQLELTEMNSEQTSSGELFSQVKKLTNDNLNKNTQ 1567

Query: 1306 LRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQ 1365
            +  L+ +    IN+++     +E +                    +LR+     +   +Q
Sbjct: 1568 IDQLKLQ----INELQDKNRNLEKQYNKLRSDALVGNQGNSESF-ELRSRVDELEGQFKQ 1622

Query: 1366 SILNINEENAQLKK-----SSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQ-- 1418
            S  +I +++ Q+++      +            +  + E +  + T+   + +S  ++  
Sbjct: 1623 SQNSIRQKDQQIQELKQLLDNQSYQSNQSNQREKEREREKEKEKQTYNKPINNSNDHENM 1682

Query: 1419 KTHEYTITLTQRNDEFENVRQ 1439
            K  EY   + Q+ +E EN+++
Sbjct: 1683 KIQEYQFIIEQQTEEIENMKR 1703



 Score =  101 bits (242), Expect = 2e-19
 Identities = 178/948 (18%), Positives = 398/948 (41%), Gaps = 86/948 (9%)

Query: 606  ENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLE 665
            +N+A+ +   +++ E      ++ + + Q KY  ++D      + +S Q    +K++ + 
Sbjct: 311  QNIADVKANQLNIEE------IEVILLRQVKYSMIQD---GYFKTKSVQFSPYVKTMSIS 361

Query: 666  EQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLE 725
            +     S+  ++      N+  D+  +   I  +EN KE+I  KL + +    +L  K  
Sbjct: 362  QITSRFSSVIQDTTS--SNMDFDRVSILNKI--VENQKEEIA-KLNSQLNNGPELNRKKT 416

Query: 726  KMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYI---ENIESELSKYKSRICRLE 782
                +K    +      +  +++ +  + + ++ + +++   E ++ +++     I +LE
Sbjct: 417  VQMKQKDQTNI----QGDLKQVEDEDLVFSNLRRKTMHLLNQEEVDEDVAVLTDYINKLE 472

Query: 783  ESIA----VMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVV- 837
            E +     V++D+   +    ++     +E QK   E  + E + +++  +    ++ V 
Sbjct: 473  EVLILKHRVVKDQNLKILEMQEKNEKIFEEIQKLKKEVQLSEVKFIDQTKITHQFEKEVN 532

Query: 838  EKQLL--EIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVE-KANRTDLAESEST 894
            EK  +  E + +NKELQ+       EN   +I L +++            +++  + E  
Sbjct: 533  EKSRIIDEYKKKNKELQENLVSAQTENNKYKIQLLEVKALEGGSANGNGQKSNSYQREVE 592

Query: 895  KYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNI 954
            + Q +   L+  +  +  E+Q L    K   ++   +   QI    + K ++N +  +  
Sbjct: 593  RIQDENARLQKKIAEL--ENQVLEQNSKSSDQNESRKLQIQITQLEQSKFLINAQLSQRE 650

Query: 955  EYVTQLEAQLQEY--KNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEIN 1012
              +TQL+ Q+Q    +NN+++    V +  + N EL     Q Q +      + + ++++
Sbjct: 651  ATITQLQRQIQGLLDENNMKSEGDQVIQERRKNAEL-----QLQLSNYQTSEKVWKSKLS 705

Query: 1013 KLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLL 1072
             +   LK++      L  K+N++  S      + +    +   +L    E    ++KQL 
Sbjct: 706  DIEHKLKEQTLINQELKTKVNSSNPSITITKDENDRNYERIREQLSLELEAKTSLTKQLF 765

Query: 1073 DSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXX 1132
             S    +EL I + ++  + + L+   + ++  + +T      +  + +       D   
Sbjct: 766  QSI---DELTIKLNQERSKSQNLQ---IEYDQLLEQTN--FRQNRSQTIQQQNQQKDQRI 817

Query: 1133 XXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVN 1192
                     L+++  +   Q+ S L      L    +    KI++LE             
Sbjct: 818  QDFQAQIEQLQLELSKAKSQQ-SQLASMHQNLQENFKAAEMKIVELEHQKRMYDRTIQEK 876

Query: 1193 QEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQK 1252
             EQ+   ++K+++LNT+ + L   + E   S+    +QR   + E  +  +  +  +++ 
Sbjct: 877  VEQVTSHETKIKELNTQKNQLDEQLTE---SLKKQSEQR--VLLESLQFQVGNKGKEYEN 931

Query: 1253 TEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEK 1312
             + ++  Q      + E++    +S+  E+  K +   +  +L+ +L  KEE +R+ QE+
Sbjct: 932  LKKKIEEQELIILGQNEKIHKVKESNEAEQNEKSILGTEQENLKKQLYMKEEQIRSRQEQ 991

Query: 1313 YADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRT-ENQSYKQMQEQSILNIN 1371
               + +QI  L     +EKV+                   RT +N+  K +++Q    IN
Sbjct: 992  INSLNDQIRNL-----NEKVS--------------SLEQQRTLQNKQVKHLEDQ----IN 1028

Query: 1372 EENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRN 1431
                +                 RV +AEA++L+L    +   +EI     E    L Q+ 
Sbjct: 1029 SREREYMTEHSKVSSERDLQKQRVIEAEAQILKLQQSDKKYKTEISNLNEE----LQQQL 1084

Query: 1432 DEFENVRQQLVEYEKRIEDLTYE--KESELAILRLKMHENANHYETMQKESEIERVKL-- 1487
               E++ +Q+ +YE +         + S++  +RL+  E  N    ++ E++ + +K   
Sbjct: 1085 LTLEHLNKQIKDYEIQQNQSRESNLENSKVQSIRLEKLEQQNQNMNIKIEAQSQEIKQYT 1144

Query: 1488 --IEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEI 1533
              IEE    ITE     ++   L KA E++V    +    LENQ I+I
Sbjct: 1145 AKIEEQLTTITELKYKVQEEESLRKAKEKQVNDKTQQIGQLENQLIKI 1192



 Score = 95.1 bits (226), Expect = 1e-17
 Identities = 187/997 (18%), Positives = 408/997 (40%), Gaps = 76/997 (7%)

Query: 235  EKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXX 294
            E++ L K +  K+ +I S +E    L      ++ + S L Q+                 
Sbjct: 970  EQENLKKQLYMKEEQIRSRQEQINSLNDQIRNLNEKVSSLEQQRTLQNKQVKHLEDQINS 1029

Query: 295  LAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGT 354
              ++ +    +  +E + +    I    ++ K  +  +    +I   N+EL+ +L T+  
Sbjct: 1030 REREYMTEHSKVSSERDLQKQRVIEAEAQILKLQQSDKKYKTEISNLNEELQQQLLTLEH 1089

Query: 355  ESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVI 414
             +K +     + +   SR+S    +        +L  +  N +   +    EI +    I
Sbjct: 1090 LNKQIKDYEIQQNQ--SRESNLENSKVQSIRLEKLEQQNQNMNIKIEAQSQEIKQYTAKI 1147

Query: 415  QSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQ-----LEHQQHMEGPSLIHVG 469
            +     + + +Y + E+++           K   I QL+     ++ + +    S   + 
Sbjct: 1148 EEQLTTITELKYKVQEEESLRKAKEKQVNDKTQQIGQLENQLIKIQEKYNQSNRSSQDIQ 1207

Query: 470  TNTEDVNEIAKVQEQLKQELNDEIKDVN-----VKDLIEKLKSAEEQITQLNDEIDAANK 524
               +D+ +   V+    Q L     + N       +  +KL S E+Q+   N+  D   K
Sbjct: 1208 NQYDDLKKKFDVELNNMQSLQSRSIEYNSLQSRYMEQGQKLSSLEKQLLDYNEISDQYQK 1267

Query: 525  NMIKVKS-----NHKLK--LKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEE 577
               +++S     + KL   +    K ID  +++ +SN ++ ++ +E H + QK A  ++ 
Sbjct: 1268 QKKELQSLTDLLDSKLATIVSHETKIIDLTNQLKESNSQLQQVRKENHEIMQKRA--QDM 1325

Query: 578  KGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKY 637
            +   QL  ++ ++G     D+ +++   E   + +   +S+L+  + +L Q    L+  Y
Sbjct: 1326 QAMAQLKQIEVENG-----DLKQQVYSHEATIQNQEALLSVLKGNQLNLEQSQMKLKIDY 1380

Query: 638  DEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIK 697
              +++K  +   +  D+    +   +L+ + D+LS   ++     ENL+L ++Q      
Sbjct: 1381 QHLDEKYNE-KLIDLDEKSKTL--FNLQNKFDSLSFRAQQSE---ENLRLVEDQR----D 1430

Query: 698  DLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKI 757
            D ++  E  + +L  Y  ++ +    +  M+A KI   L +  H  Q K +    ++ ++
Sbjct: 1431 DYQSRYELALQELDIYKGKDKE----INLMAANKIE--LQEQMHSVQKKNKV---LEREL 1481

Query: 758  QERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERK-ADQLGSYLQ---EKQKAY 813
            Q     +++ ES++ + +  I + E+ I  +E     L+    +   SY Q   E  +  
Sbjct: 1482 QVSQNALQSKESDILQLQHTIQKKEQQITTLEGTIVKLKADLTNSKNSYEQLQLELTEMN 1541

Query: 814  SEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQ 873
            SE T    EL +++  L + +     Q+ +++ +  ELQ KN+ L ++   L+       
Sbjct: 1542 SEQT-SSGELFSQVKKLTNDNLNKNTQIDQLKLQINELQDKNRNLEKQYNKLRSDALVGN 1600

Query: 874  QHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIE-DLEIEF 932
            Q  +   E  +R D  E +  + Q  +R  +  ++ +         Q  +  + + E E 
Sbjct: 1601 QGNSESFELRSRVDELEGQFKQSQNSIRQKDQQIQELKQLLDNQSYQSNQSNQREKERER 1660

Query: 933  NTQIESAIRDKKVLNEKYEKNI---EYVTQLEAQLQEYKN---NIENLNMNVEELNKMNL 986
              + E    +K + N    +N+   EY   +E Q +E +N   N + L   + EL  + +
Sbjct: 1661 EKEKEKQTYNKPINNSNDHENMKIQEYQFIIEQQTEEIENMKRNSQGLGEELTELLTLVV 1720

Query: 987  EL-IDKHVQKQQTQSPDYTEQ--YINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMV 1043
             + + K ++K Q       +Q     + NK   + ++ DE+++   QK+   +  Y++  
Sbjct: 1721 NVFLKKKIKKDQLNIATVLDQIKLFQKENKTLTIREEDDEQLVL--QKLQQYRGDYINFR 1778

Query: 1044 SDYESKLAQFTT----KLENMEEEMQRVSKQLLDSKQHNEEL----QILVREQ------D 1089
               E  L + T      L+ + E   +  K+ +D     E L    ++L+  Q       
Sbjct: 1779 FRVEQNLTRITVLKQQMLQIISEAKIQGKKKDVDKNMDVENLVMYFKLLLDSQAVQYSNQ 1838

Query: 1090 DQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEE 1149
             Q+ +  E +L    N    +G II    E +S                   +K++++++
Sbjct: 1839 LQLCQQYEAELRSYQNNTSPQGQIIQQVKELLSKAPFLTQQQIYQFTEPKVSIKLRKDQD 1898

Query: 1150 FIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELT 1186
                R +L+ ++ ++         K  QL  +NT LT
Sbjct: 1899 QEDARLLLEARNQQIQWLKNLINEKQDQLAVMNTYLT 1935



 Score = 79.0 bits (186), Expect = 1e-12
 Identities = 165/879 (18%), Positives = 354/879 (40%), Gaps = 89/879 (10%)

Query: 732  ISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDR 791
            IS++ ++ +   Q    +    D ++   +  +EN + E++K  S+   L     +   +
Sbjct: 360  ISQITSRFSSVIQDTTSSNMDFD-RVSILNKIVENQKEEIAKLNSQ---LNNGPELNRKK 415

Query: 792  RYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENK-- 849
               +++K DQ    +Q   K   +  +    L  +   L++ + V E   +  ++ NK  
Sbjct: 416  TVQMKQK-DQTN--IQGDLKQVEDEDLVFSNLRRKTMHLLNQEEVDEDVAVLTDYINKLE 472

Query: 850  -ELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLES-NL 907
              L  K++++  ++QNL+I   +MQ+    + E        E +  K + QL +++  + 
Sbjct: 473  EVLILKHRVV--KDQNLKIL--EMQEKNEKIFE--------EIQKLKKEVQLSEVKFIDQ 520

Query: 908  KRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEA----- 962
             +ITH+ +  + +K + I++ + + N +++  +   +  N KY+  +  V  LE      
Sbjct: 521  TKITHQFEKEVNEKSRIIDEYKKK-NKELQENLVSAQTENNKYKIQLLEVKALEGGSANG 579

Query: 963  ---QLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLK 1019
               +   Y+  +E +      L K   EL +  V +Q ++S D      NE  KL   + 
Sbjct: 580  NGQKSNSYQREVERIQDENARLQKKIAEL-ENQVLEQNSKSSDQ-----NESRKLQIQIT 633

Query: 1020 QKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLEN---MEEEMQRVSKQLLDSKQ 1076
            Q ++    +N +++  + +   +    +  L +   K E    ++E  +    QL  S  
Sbjct: 634  QLEQSKFLINAQLSQREATITQLQRQIQGLLDENNMKSEGDQVIQERRKNAELQLQLSNY 693

Query: 1077 HNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXX 1136
               E ++   +  D   +LKE  L  +    K      S TI    +D N          
Sbjct: 694  QTSE-KVWKSKLSDIEHKLKEQTLINQELKTKVNSSNPSITITKDENDRNYERIREQLSL 752

Query: 1137 XXXXXLKVQEEE-EFIQERSVLQEQSAKLNTELQECYTKIIQL----ETLNTELTGHDVV 1191
                   + ++  + I E ++   Q    +  LQ  Y ++++     +  +  +   +  
Sbjct: 753  ELEAKTSLTKQLFQSIDELTIKLNQERSKSQNLQIEYDQLLEQTNFRQNRSQTIQQQNQQ 812

Query: 1192 NQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQ 1251
              ++I   ++++EQL  E     S  ++L S   +   Q  F+ AE+    L  ++  + 
Sbjct: 813  KDQRIQDFQAQIEQLQLELSKAKSQQSQLASMHQNL--QENFKAAEMKIVELEHQKRMYD 870

Query: 1252 KTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQE 1311
            +T  E   Q+++ E+K ++L           T K    EQ+T    K  ++   L +LQ 
Sbjct: 871  RTIQEKVEQVTSHETKIKEL----------NTQKNQLDEQLTESLKKQSEQRVLLESLQF 920

Query: 1312 KYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNIN 1371
            +  +   + E L+ +IE++++                    + +  +  +  E+SIL   
Sbjct: 921  QVGNKGKEYENLKKKIEEQELIILGQNEKIH----------KVKESNEAEQNEKSILGTE 970

Query: 1372 EENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRN 1431
            +EN  LKK              ++N    ++  L  ++   + +   +  +      Q N
Sbjct: 971  QEN--LKKQLYMKEEQIRSRQEQINSLNDQIRNLNEKVSSLEQQRTLQNKQVKHLEDQIN 1028

Query: 1432 DEFENVRQQLVEYEK--RIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIE 1489
                  R+ + E+ K     DL  ++  E     LK+ ++   Y+T       E   L E
Sbjct: 1029 ---SREREYMTEHSKVSSERDLQKQRVIEAEAQILKLQQSDKKYKT-------EISNLNE 1078

Query: 1490 ELNVKITESVSLNKQVAEL----NKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQN 1545
            EL  ++     LNKQ+ +     N++ E  +  +      LE  E +   +N +I     
Sbjct: 1079 ELQQQLLTLEHLNKQIKDYEIQQNQSRESNLENSKVQSIRLEKLEQQNQNMNIKIEAQSQ 1138

Query: 1546 MVRASSSKIQKHVSFASDTKQ--GRDEQLDNTMNKELLD 1582
             ++  ++KI++ ++  ++ K     +E L     K++ D
Sbjct: 1139 EIKQYTAKIEEQLTTITELKYKVQEEESLRKAKEKQVND 1177



 Score = 65.7 bits (153), Expect = 1e-08
 Identities = 109/607 (17%), Positives = 254/607 (41%), Gaps = 46/607 (7%)

Query: 956  YVTQLEAQLQEYKNNIENLNMNVEEL--NKMNLELIDKHVQKQQTQSPDYTEQYINEINK 1013
            Y    +AQ +  K     L+ N+ ++  N++N+E I+  + +Q   S      +  +  +
Sbjct: 291  YSLHQQAQDEFIKFIASALSQNIADVKANQLNIEEIEVILLRQVKYSMIQDGYFKTKSVQ 350

Query: 1014 LNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLD 1073
             +  +K     I  +  + ++      S   D++ +++     +EN +EE+ +++ QL +
Sbjct: 351  FSPYVKTMS--ISQITSRFSSVIQDTTSSNMDFD-RVSILNKIVENQKEEIAKLNSQLNN 407

Query: 1074 SKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXX 1133
              + N       R++  Q+K+  +T +  ++   + E ++ S+         N  +    
Sbjct: 408  GPELN-------RKKTVQMKQKDQTNIQGDLKQVEDEDLVFSNLRRKTMHLLNQEEVDED 460

Query: 1134 XXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQ-LETLNTELTGHDV-- 1190
                     K+  EE  I +  V+++Q+ K+  E+QE   KI + ++ L  E+   +V  
Sbjct: 461  VAVLTDYINKL--EEVLILKHRVVKDQNLKI-LEMQEKNEKIFEEIQKLKKEVQLSEVKF 517

Query: 1191 VNQEQI-NQLKSKLEQLNTENDNLLSTVAELRSSISSA-VDQRGFEIAELWKQHLAQREA 1248
            ++Q +I +Q + ++ + +   D       EL+ ++ SA  +   ++I  L  + L    A
Sbjct: 518  IDQTKITHQFEKEVNEKSRIIDEYKKKNKELQENLVSAQTENNKYKIQLLEVKALEGGSA 577

Query: 1249 DFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRN 1308
            +    +           + Y++ ++ +Q        KI  +E     QN     +   R 
Sbjct: 578  NGNGQK----------SNSYQREVERIQDENARLQKKIAELENQVLEQNSKSSDQNESRK 627

Query: 1309 LQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSIL 1368
            LQ +   +     ++ +++   +                    L  EN    + +   ++
Sbjct: 628  LQIQITQLEQSKFLINAQLSQREATITQLQRQIQG--------LLDENNM--KSEGDQVI 677

Query: 1369 NINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLT 1428
                +NA+L+               +++D E K+ E T   +   +++       TIT  
Sbjct: 678  QERRKNAELQLQLSNYQTSEKVWKSKLSDIEHKLKEQTLINQELKTKVNSSNPSITITKD 737

Query: 1429 QRNDEFENVRQQL-VEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKL 1487
            + +  +E +R+QL +E E +   LT +    +  L +K+++  +  + +Q    IE  +L
Sbjct: 738  ENDRNYERIREQLSLELEAK-TSLTKQLFQSIDELTIKLNQERSKSQNLQ----IEYDQL 792

Query: 1488 IEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMV 1547
            +E+ N +   S ++ +Q  + ++ +++  A+  ++Q  L   + +   L     NLQ   
Sbjct: 793  LEQTNFRQNRSQTIQQQNQQKDQRIQDFQAQIEQLQLELSKAKSQQSQLASMHQNLQENF 852

Query: 1548 RASSSKI 1554
            +A+  KI
Sbjct: 853  KAAEMKI 859


>UniRef50_UPI00006CB6DE Cluster: hypothetical protein TTHERM_00494050;
            n=1; Tetrahymena thermophila SB210|Rep: hypothetical
            protein TTHERM_00494050 - Tetrahymena thermophila SB210
          Length = 1181

 Score =  126 bits (305), Expect = 4e-27
 Identities = 227/1129 (20%), Positives = 489/1129 (43%), Gaps = 96/1129 (8%)

Query: 476  NEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDE---IDAANKNMIK---- 528
            + +  + ++LK      + +   ++ +EK++  E ++ QL  E   ID +    ++    
Sbjct: 45   SSLFNMSQELKYSTPSILNNQEKEEKLEKIRQMESRMKQLQQEKMQIDLSVSETVERTQL 104

Query: 529  VKSNHKLK--LKQMQKTIDNFSKVSDSNKEIVRLTEELH---HLSQKVAELEEEKGNL-- 581
            V+ N+ LK  L  M+  I  + +    +   V L+ E         KV +L +E  NL  
Sbjct: 105  VQENNDLKNQLYAMELQIKQYQQHQQQDLTEVSLSLEKQKQIEFENKVNQLVKENANLIE 164

Query: 582  QLHLVDYDSGRMIESD----VYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKY 637
            Q ++   D   +I+       + +++E + LA  R+     LE +   L  E+  +Q   
Sbjct: 165  QFNMAKQDLELLIKQKEVDRAHIQVLEEKLLAFERMN--EKLEEKNIQLRDEMIKIQYHS 222

Query: 638  DEVEDKLADIS---QLQSDQVCSEIKSVHLEE----QIDALSASKKELALVIENLKLDKE 690
            +  E+ + D+    +  +D +  E+K+  + E    Q      S K+L L   +L+ + E
Sbjct: 223  NTDENYVQDLKNQYKRVNDLLDLELKNKKVYEMQLIQAKQSQQSLKQLELEYTSLQQNLE 282

Query: 691  QLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQ 750
            +L    ++L  +   I    Q Y  EN      LEK S  KI +L  +++  +Q+    Q
Sbjct: 283  KLKKLNQELTIENNTIK---QQYYSENQK-NIILEKNSL-KIYQLQKELDISQQNTQDIQ 337

Query: 751  FGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQ 810
              + A+ Q++   ++N + EL   + +  +++E I    + +   ++KA QL     E+Q
Sbjct: 338  MQL-AQAQKQIQELKN-QCELKMLEEK--QMKEQIIKESEIKVDSQQKAFQL-----EQQ 388

Query: 811  KAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLS 870
            K+  E  I+  EL   +  L +  +  ++++++ + +NK+L+     L ++ Q L+  L 
Sbjct: 389  KSEKEQQIR--ELKRDIEQLKEDLQDQKEKVIQEQQKNKDLKNNEYSLTKDIQTLEEQLQ 446

Query: 871  DMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEI 930
            ++Q  ++ L EK  R   A+ +S   Q ++ + +  +  I  + +  I+Q  K+ + LE 
Sbjct: 447  NIQNDHDKLQEKYAR---AQKQS---QKEIEESQMIIDEIKSQTEGEILQLTKKCQKLE- 499

Query: 931  EFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVE-ELNKMNLELI 989
                           +NE  E+N++ V    ++L+E+K    +  +  E E  K+N +L 
Sbjct: 500  --------------SINEDLEQNLKIV---RSELEEFKKKHGSTKLKYEDEFVKVN-QLQ 541

Query: 990  DKHVQKQQT--QSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYE 1047
             K  +++ T  Q  +  E +  +  KL   L +  E+   ++Q+  N Q+  M  VSD +
Sbjct: 542  RKLDEREDTIKQQKEQIETHKLKEQKLTEQLGKIQEQTKIISQEKEN-QLREMIKVSDMK 600

Query: 1048 SKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIP 1107
             KLA+   ++E  E EM+ + ++++   +  ++   +++E D Q  E++   LT + +  
Sbjct: 601  VKLAE--RQMEQKENEMKLLREEMVYLSEQLDQGSEVMKEYDRQCIEIE--MLTQQKDQL 656

Query: 1108 KTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLK--VQEEEEFIQERSVLQEQSAKLN 1165
            +   MI+   I+  + +   +             L+  V ++E  IQE    +    +  
Sbjct: 657  QQTIMILEKQIDEKNLEFMQLQQAYRDIEIDREKLQETVIKQESIIQEAKQTENHIREEK 716

Query: 1166 TELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSIS 1225
             ++ E + ++   + ++ E      V ++Q  +L  KL+    E   LL  + + +  + 
Sbjct: 717  RKVIEQFKQVSYEKRISDEKALVTEVVEKQNEELLQKLDSTRNEMKQLLEQLRQEKLQVE 776

Query: 1226 SAVDQ---RGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEE 1282
               ++   +   I EL +     R    +K + E R+++   + K+E +   V  + Q E
Sbjct: 777  KLTEENEKQNQRIKELEESQSVMRAIQSEKEKEESRLEVEMLKMKHESM---VSLNKQYE 833

Query: 1283 TNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXX 1342
               +   + +  L+  L++  + +  LQ++  +   QI  LR E++              
Sbjct: 834  DEILQLSKDIQELEKSLKNSYKRINALQQEIEEKEQQISDLRKELDLVDRQVILKINHEK 893

Query: 1343 XXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKV 1402
                    DL+ E +  + +Q+Q  L +   +A+  ++                D + K+
Sbjct: 894  SQYQTQVTDLQLEVEQMRNLQQQIAL-LKSNDAKYIETIASLQKEINKLEIDNQDLQFKI 952

Query: 1403 LELTHQLELKDSEIYQKTH----EYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESE 1458
             +   QL+  +    Q  H    ++ I L  +  + +  R Q++E + +     YE++++
Sbjct: 953  KQQDLQLQKTEIAFNQNIHYQASQHVIDLETQIHQ-QQARNQILEQQLKAMTEKYEQKAK 1011

Query: 1459 LAILRLKMHENANHYETMQKESEI-ERVKLIEELNVKITESVSLNKQVAELNKALEEEVA 1517
            L   R  ++ +  H    Q   +I +   ++        ++      ++  N  L     
Sbjct: 1012 L-FERYGVNFDPQHPNYNQTVKKIPQPTNMLTSPPFSPRKNQVSTASISNNNNPLFLSPP 1070

Query: 1518 KTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQ 1566
            +  + Q  L NQ+     + +     QN++ + SS+ Q+  +F+S   Q
Sbjct: 1071 QKLQSQNLLFNQQ----AIPNSSQQTQNLIYSPSSQNQEQFNFSSRQNQ 1115



 Score =  119 bits (286), Expect = 8e-25
 Identities = 179/915 (19%), Positives = 392/915 (42%), Gaps = 89/915 (9%)

Query: 672  SASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEK 731
            SA K++      N   D    Y     L N  +++     + I  N +  +KLEK     
Sbjct: 21   SAQKRQYTFTFNNESKDLSS-YQAGSSLFNMSQELKYSTPS-ILNNQEKEEKLEK----- 73

Query: 732  ISELLAKINHEEQSKIQTQFGIDAKIQERDLYIEN---------IESELSKYKSRICR-- 780
            I ++ +++   +Q K+Q    +   ++   L  EN         +E ++ +Y+    +  
Sbjct: 74   IRQMESRMKQLQQEKMQIDLSVSETVERTQLVQENNDLKNQLYAMELQIKQYQQHQQQDL 133

Query: 781  LEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDE---LVNRLAVLMDHDRVV 837
             E S+++ + ++   E K +QL   ++E      ++ + + +   L+ +  V   H +V+
Sbjct: 134  TEVSLSLEKQKQIEFENKVNQL---VKENANLIEQFNMAKQDLELLIKQKEVDRAHIQVL 190

Query: 838  EKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQ 897
            E++LL  E  N++L++KN  L +E   +Q         Y++  ++    DL      K  
Sbjct: 191  EEKLLAFERMNEKLEEKNIQLRDEMIKIQ---------YHSNTDENYVQDL--KNQYKRV 239

Query: 898  TQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYV 957
              L DLE   K++         Q ++ ++ LE+E+ T ++  +   K LN+  E  IE  
Sbjct: 240  NDLLDLELKNKKVYEMQLIQAKQSQQSLKQLELEY-TSLQQNLEKLKKLNQ--ELTIENN 296

Query: 958  TQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNAL 1017
            T    + Q Y  N +N+   + E N + +  + K +   Q  + D   Q      ++  L
Sbjct: 297  T---IKQQYYSENQKNI---ILEKNSLKIYQLQKELDISQQNTQDIQMQLAQAQKQIQEL 350

Query: 1018 LKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQH 1077
              Q   E+  L +K    Q+   S +   +S+   F  + +  E+E Q++ +   D +Q 
Sbjct: 351  KNQC--ELKMLEEKQMKEQIIKESEIK-VDSQQKAFQLEQQKSEKE-QQIRELKRDIEQL 406

Query: 1078 NEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXX 1137
             E+L      QD + K ++E +   ++   K     ++  I+ + +   N+         
Sbjct: 407  KEDL------QDQKEKVIQEQQKNKDL---KNNEYSLTKDIQTLEEQLQNIQNDHDKLQE 457

Query: 1138 XXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQIN 1197
                 + Q ++E  + + ++ E  ++   E+ +   K  +LE++N +L  +  + + ++ 
Sbjct: 458  KYARAQKQSQKEIEESQMIIDEIKSQTEGEILQLTKKCQKLESINEDLEQNLKIVRSELE 517

Query: 1198 QLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHEL 1257
            + K K      + ++    V +L+  +    D    +  ++    L +++   Q  + + 
Sbjct: 518  EFKKKHGSTKLKYEDEFVKVNQLQRKLDEREDTIKQQKEQIETHKLKEQKLTEQLGKIQE 577

Query: 1258 RVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVI 1317
            + ++ + + K  QL + ++ S  +       MEQ  +    L+++  +L    ++ ++V+
Sbjct: 578  QTKIIS-QEKENQLREMIKVSDMKVKLAERQMEQKENEMKLLREEMVYLSEQLDQGSEVM 636

Query: 1318 NQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQL 1377
             + +  R  IE E +                  D   +N  + Q+Q Q+  +I  +  +L
Sbjct: 637  KEYD--RQCIEIEMLTQQKDQLQQTIMILEKQID--EKNLEFMQLQ-QAYRDIEIDREKL 691

Query: 1378 KKS---SXXXXXXXXXXXXRVNDAEAKVLE----LTHQLELKD-----SEIYQKTHEYTI 1425
            +++                 + + + KV+E    ++++  + D     +E+ +K +E  +
Sbjct: 692  QETVIKQESIIQEAKQTENHIREEKRKVIEQFKQVSYEKRISDEKALVTEVVEKQNEELL 751

Query: 1426 -TLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIER 1484
              L    +E + + +QL + + ++E LT E E +   ++ ++ E+ +    +Q E E E 
Sbjct: 752  QKLDSTRNEMKQLLEQLRQEKLQVEKLTEENEKQNQRIK-ELEESQSVMRAIQSEKEKEE 810

Query: 1485 VKL-IEELNVKITESVSLNKQ-----------VAELNKALEEEVAKTNEMQTALENQEIE 1532
             +L +E L +K    VSLNKQ           + EL K+L+    + N +Q  +E +E +
Sbjct: 811  SRLEVEMLKMKHESMVSLNKQYEDEILQLSKDIQELEKSLKNSYKRINALQQEIEEKEQQ 870

Query: 1533 IVTLNDEITNLQNMV 1547
            I  L  E+  +   V
Sbjct: 871  ISDLRKELDLVDRQV 885



 Score =  116 bits (280), Expect = 4e-24
 Identities = 192/984 (19%), Positives = 437/984 (44%), Gaps = 95/984 (9%)

Query: 337  QIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQ 396
            Q+ Q N +L+N+L  M  + K      ++    +S    +    + ++  +QL  E  N 
Sbjct: 103  QLVQENNDLKNQLYAMELQIKQYQQHQQQDLTEVSLSLEKQKQIEFENKVNQLVKENANL 162

Query: 397  DTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEH 456
                 + K +   LE++I+    D    + V+ EK             K+  +    ++ 
Sbjct: 163  IEQFNMAKQD---LELLIKQKEVDRAHIQ-VLEEKLLAFERMNEKLEEKNIQLRDEMIKI 218

Query: 457  QQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDL-IEKLKSAEEQITQL 515
            Q H          T+   V ++    +++   L+ E+K+  V ++ + + K +++ + QL
Sbjct: 219  QYHSN--------TDENYVQDLKNQYKRVNDLLDLELKNKKVYEMQLIQAKQSQQSLKQL 270

Query: 516  NDEIDAANKNMIKVKS-NHKLKLKQMQKTIDNFSKVSDSNKEIV--RLTEELHHLSQKVA 572
              E  +  +N+ K+K  N +L ++    TI      S++ K I+  + + +++ L +++ 
Sbjct: 271  ELEYTSLQQNLEKLKKLNQELTIEN--NTIKQ-QYYSENQKNIILEKNSLKIYQLQKELD 327

Query: 573  ELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQ-KFDLVQELH 631
              ++   ++Q+ L    + + I+    K   E++ L E ++K   + ES+ K D  Q+  
Sbjct: 328  ISQQNTQDIQMQLAQ--AQKQIQE--LKNQCELKMLEEKQMKEQIIKESEIKVDSQQKAF 383

Query: 632  ILQQKYDEVEDKLA----DISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKL 687
             L+Q+  E E ++     DI QL+ D    + K +  +++   L  ++  L   I+ L+ 
Sbjct: 384  QLEQQKSEKEQQIRELKRDIEQLKEDLQDQKEKVIQEQQKNKDLKNNEYSLTKDIQTLEE 443

Query: 688  DKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKI 747
              + +      L+        + Q  I+E+  + D+++  +  +I +L  K   ++   I
Sbjct: 444  QLQNIQNDHDKLQEKYARAQKQSQKEIEESQMIIDEIKSQTEGEILQLTKKC--QKLESI 501

Query: 748  QTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQ 807
                  + KI   +L     E    K+ S   + E+    +      L+RK D+    ++
Sbjct: 502  NEDLEQNLKIVRSEL-----EEFKKKHGSTKLKYEDEFVKVN----QLQRKLDEREDTIK 552

Query: 808  EKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKN--QILLEENQNL 865
            ++++    + ++E +L  +L  + +  +++ +   E E++ +E+ K +  ++ L E Q +
Sbjct: 553  QQKEQIETHKLKEQKLTEQLGKIQEQTKIISQ---EKENQLREMIKVSDMKVKLAERQ-M 608

Query: 866  QISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEI 925
            +   ++M+     +V  + + D       +Y  Q  ++E   ++     QT+++  +K+I
Sbjct: 609  EQKENEMKLLREEMVYLSEQLDQGSEVMKEYDRQCIEIEMLTQQKDQLQQTIMI-LEKQI 667

Query: 926  EDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMN 985
            ++  +EF  Q++ A RD ++  EK +   E V + E+ +QE K   EN   ++ E     
Sbjct: 668  DEKNLEF-MQLQQAYRDIEIDREKLQ---ETVIKQESIIQEAKQT-EN---HIRE----- 714

Query: 986  LELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSD 1045
                +K    +Q +   Y ++  +E   +  ++++++EE++   QK+++ +     ++  
Sbjct: 715  ----EKRKVIEQFKQVSYEKRISDEKALVTEVVEKQNEELL---QKLDSTRNEMKQLLEQ 767

Query: 1046 YESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMN 1105
               +  Q     E  E++ QR+ K+L       EE Q ++R    + KE +E++L  EM 
Sbjct: 768  LRQEKLQVEKLTEENEKQNQRI-KEL-------EESQSVMRAIQSE-KEKEESRLEVEML 818

Query: 1106 IPKTEGMI-----ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQ 1160
              K E M+         I  +S D   ++            L+ QE EE  Q+ S L+++
Sbjct: 819  KMKHESMVSLNKQYEDEILQLSKDIQELEKSLKNSYKRINALQ-QEIEEKEQQISDLRKE 877

Query: 1161 SAKLNTE-LQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAE 1219
               ++ + + +   +  Q +T  T+L     +  EQ+  L+ ++  L + +   + T+A 
Sbjct: 878  LDLVDRQVILKINHEKSQYQTQVTDLQ----LEVEQMRNLQQQIALLKSNDAKYIETIAS 933

Query: 1220 LRSSISS-AVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSS 1278
            L+  I+   +D +  +        + Q++   QKTE      +    S++  ++D     
Sbjct: 934  LQKEINKLEIDNQDLQF------KIKQQDLQLQKTEIAFNQNIHYQASQH--VIDLETQI 985

Query: 1279 TQEETNKIVTMEQVTSLQNKLQDK 1302
             Q++    +  +Q+ ++  K + K
Sbjct: 986  HQQQARNQILEQQLKAMTEKYEQK 1009



 Score = 95.5 bits (227), Expect = 1e-17
 Identities = 171/885 (19%), Positives = 376/885 (42%), Gaps = 54/885 (6%)

Query: 212  EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271
            E+   Q+ K   N I      K + + L+K  E     I  LEE  KLL   R    LE 
Sbjct: 149  ENKVNQLVKENANLIEQFNMAKQDLELLIKQKEVDRAHIQVLEE--KLLAFERMNEKLEE 206

Query: 272  S--KLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIE 329
               +L  E+ +              L  Q    +     E++ K   E+  + +  +  +
Sbjct: 207  KNIQLRDEMIKIQYHSNTDENYVQDLKNQYKRVNDLLDLELKNKKVYEM-QLIQAKQSQQ 265

Query: 330  LLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQL 389
             L+ L  +     + LE KL  +  E    ++  K+     S         K      QL
Sbjct: 266  SLKQLELEYTSLQQNLE-KLKKLNQELTIENNTIKQ--QYYSENQKNIILEKNSLKIYQL 322

Query: 390  SSE-TLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTL 448
              E  ++Q   + I + ++A+ +  IQ L      K  ++ EK              D+ 
Sbjct: 323  QKELDISQQNTQDI-QMQLAQAQKQIQELKNQCELK--MLEEKQMKEQIIKESEIKVDSQ 379

Query: 449  IAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQ---LKQELNDEIKDVNVKDLIEKL 505
                QLE Q+  +   +  +  + E + E  + Q++    +Q+ N ++K+ N   L + +
Sbjct: 380  QKAFQLEQQKSEKEQQIRELKRDIEQLKEDLQDQKEKVIQEQQKNKDLKN-NEYSLTKDI 438

Query: 506  KSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELH 565
            ++ EEQ+  + ++ D   +   + +   + ++++ Q  ID     S +  EI++LT++  
Sbjct: 439  QTLEEQLQNIQNDHDKLQEKYARAQKQSQKEIEESQMIIDEIK--SQTEGEILQLTKKCQ 496

Query: 566  HLSQKVAELEEE----KGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLES 621
             L     +LE+     +  L+     + S ++   D + K+ +++   + R   I   + 
Sbjct: 497  KLESINEDLEQNLKIVRSELEEFKKKHGSTKLKYEDEFVKVNQLQRKLDEREDTIKQQKE 556

Query: 622  QKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKK--ELA 679
            Q      +   L ++  +++++   ISQ + +Q+   IK   ++ ++      +K  E+ 
Sbjct: 557  QIETHKLKEQKLTEQLGKIQEQTKIISQEKENQLREMIKVSDMKVKLAERQMEQKENEMK 616

Query: 680  LVIENLKLDKEQL-YGTIKDLENDKEDIMNKLQNYIQENMDLTDK-LEKMSAEKISELLA 737
            L+ E +    EQL  G+    E D++ I  ++    ++ +  T   LEK   EK  E + 
Sbjct: 617  LLREEMVYLSEQLDQGSEVMKEYDRQCIEIEMLTQQKDQLQQTIMILEKQIDEKNLEFMQ 676

Query: 738  KINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLER 797
                    +I  +     K+QE  +  E+I  E  + ++ I R E+   + + ++ S E+
Sbjct: 677  LQQAYRDIEIDRE-----KLQETVIKQESIIQEAKQTENHI-REEKRKVIEQFKQVSYEK 730

Query: 798  KADQLGSYLQEKQKAYSEYTIQE-DELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQ 856
            +     + + E  +  +E  +Q+ D   N +  L++    + ++ L++E   +E +K+NQ
Sbjct: 731  RISDEKALVTEVVEKQNEELLQKLDSTRNEMKQLLEQ---LRQEKLQVEKLTEENEKQNQ 787

Query: 857  IL--LEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEH 914
             +  LEE+Q++  ++   ++   + +E      +          Q  D    L +   E 
Sbjct: 788  RIKELEESQSVMRAIQSEKEKEESRLE-VEMLKMKHESMVSLNKQYEDEILQLSKDIQEL 846

Query: 915  QTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENL 974
            +  +    K I  L+ E   + E  I D +   +  ++ +  + ++  +  +Y+  + +L
Sbjct: 847  EKSLKNSYKRINALQQEIEEK-EQQISDLRKELDLVDRQV--ILKINHEKSQYQTQVTDL 903

Query: 975  NMNVEELNKMNLEL-IDKHVQKQQTQSPDYTEQYINEI----NKLNALLKQKDEEI---- 1025
             + VE++  +  ++ + K    +  ++    ++ IN++      L   +KQ+D ++    
Sbjct: 904  QLEVEQMRNLQQQIALLKSNDAKYIETIASLQKEINKLEIDNQDLQFKIKQQDLQLQKTE 963

Query: 1026 IALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQ 1070
            IA NQ I + Q S    V D E+++ Q   + + +E++++ ++++
Sbjct: 964  IAFNQNI-HYQAS--QHVIDLETQIHQQQARNQILEQQLKAMTEK 1005



 Score = 81.4 bits (192), Expect = 2e-13
 Identities = 136/742 (18%), Positives = 313/742 (42%), Gaps = 65/742 (8%)

Query: 847  ENKELQKKN-QILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLES 905
            EN+E   +N Q L    Q  Q + +   +  +    +A  +    S+  KY T    L +
Sbjct: 6    ENEEFGDENSQNLHNSAQKRQYTFTFNNESKDLSSYQAGSSLFNMSQELKYSTP-SILNN 64

Query: 906  NLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYE-KNIEYVTQLEAQL 964
              K    E    +  + K+++  +++ +  +   +   +++ E  + KN  Y   +E Q+
Sbjct: 65   QEKEEKLEKIRQMESRMKQLQQEKMQIDLSVSETVERTQLVQENNDLKNQLYA--MELQI 122

Query: 965  QEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEE 1024
            ++Y+ + +      ++L +++L L  +   + + +     ++  N I + N  + ++D E
Sbjct: 123  KQYQQHQQ------QDLTEVSLSLEKQKQIEFENKVNQLVKENANLIEQFN--MAKQDLE 174

Query: 1025 IIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQIL 1084
            ++   ++++ A +  +      E KL  F    E +EE+  ++  +++  + H+   +  
Sbjct: 175  LLIKQKEVDRAHIQVL------EEKLLAFERMNEKLEEKNIQLRDEMIKIQYHSNTDENY 228

Query: 1085 VREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKV 1144
            V++  +Q K + +  L  E+   K   M +    +        ++            LK 
Sbjct: 229  VQDLKNQYKRVNDL-LDLELKNKKVYEMQLIQA-KQSQQSLKQLELEYTSLQQNLEKLKK 286

Query: 1145 QEEEEFIQERSVLQEQSAK--LNTELQECYTKIIQLET------LNTELTGHDVVN-QEQ 1195
              +E  I+  ++ Q+  ++   N  L++   KI QL+        NT+     +   Q+Q
Sbjct: 287  LNQELTIENNTIKQQYYSENQKNIILEKNSLKIYQLQKELDISQQNTQDIQMQLAQAQKQ 346

Query: 1196 INQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEH 1255
            I +LK++ E    E   +   + +  S I     Q+ F++    +Q  +++E   ++ + 
Sbjct: 347  IQELKNQCELKMLEEKQMKEQIIK-ESEIKVDSQQKAFQL----EQQKSEKEQQIRELKR 401

Query: 1256 ELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYAD 1315
            ++       + + E+++   Q +   + N+    + + +L+ +LQ+ +     LQEKYA 
Sbjct: 402  DIEQLKEDLQDQKEKVIQEQQKNKDLKNNEYSLTKDIQTLEEQLQNIQNDHDKLQEKYAR 461

Query: 1316 VINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENA 1375
               Q +    EIE+ ++                    + + +S  +  EQ++  +  E  
Sbjct: 462  AQKQSQ---KEIEESQMIIDEIKSQTEGEILQLTKKCQ-KLESINEDLEQNLKIVRSELE 517

Query: 1376 QLKKSSXXXXXXXXXXXXRVNDAEAKVLEL------------THQL-ELKDSEIYQKTHE 1422
            + KK              +VN  + K+ E             TH+L E K +E   K  E
Sbjct: 518  EFKKKHGSTKLKYEDEFVKVNQLQRKLDEREDTIKQQKEQIETHKLKEQKLTEQLGKIQE 577

Query: 1423 YTITLTQRNDEFENVRQQLVEYE----KRIEDLTYEKESELAILRLKMHENANHYETMQK 1478
             T  ++Q   E EN  +++++      K  E    +KE+E+ +LR    E     E + +
Sbjct: 578  QTKIISQ---EKENQLREMIKVSDMKVKLAERQMEQKENEMKLLR---EEMVYLSEQLDQ 631

Query: 1479 ESEI--ERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTL 1536
             SE+  E  +   E+ +   +   L + +  L K ++E+  +  ++Q A  + EI+   L
Sbjct: 632  GSEVMKEYDRQCIEIEMLTQQKDQLQQTIMILEKQIDEKNLEFMQLQQAYRDIEIDREKL 691

Query: 1537 NDEITNLQNMVRASSSKIQKHV 1558
             + +   +++++  + + + H+
Sbjct: 692  QETVIKQESIIQ-EAKQTENHI 712



 Score = 81.0 bits (191), Expect = 2e-13
 Identities = 151/809 (18%), Positives = 355/809 (43%), Gaps = 56/809 (6%)

Query: 149  NTIKEKDNALSV--LQVKMKIMETTILDLQEKINE-KDQIIEAKNKATTXXXXXXXXXXX 205
            N I EK N+L +  LQ ++ I +    D+Q ++ + + QI E KN+              
Sbjct: 309  NIILEK-NSLKIYQLQKELDISQQNTQDIQMQLAQAQKQIQELKNQCELKMLEEKQMKEQ 367

Query: 206  XXXXXX--EDTKQQMTKMQENFIAMEAEWKDEK---QRLLKDIESKDVRISSLEEANKLL 260
                     D++Q+  ++++     E + ++ K   ++L +D++ +  ++   ++ NK L
Sbjct: 368  IIKESEIKVDSQQKAFQLEQQKSEKEQQIRELKRDIEQLKEDLQDQKEKVIQEQQKNKDL 427

Query: 261  EAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIAN 320
            +   + ++ +   L ++L+                 KQS +   E +  I+E  S     
Sbjct: 428  KNNEYSLTKDIQTLEEQLQNIQNDHDKLQEKYARAQKQSQKEIEESQMIIDEIKSQTEGE 487

Query: 321  MTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTAS 380
            + +LTKK + LE +N  + Q  K + ++L     E K      K GS  +  +      +
Sbjct: 488  ILQLTKKCQKLESINEDLEQNLKIVRSEL----EEFK-----KKHGSTKLKYEDEFVKVN 538

Query: 381  KMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXX 440
            +++    +   +T+ Q  + +I  +++ K + + + L K + ++  +IS++         
Sbjct: 539  QLQRKLDE-REDTIKQQKE-QIETHKL-KEQKLTEQLGK-IQEQTKIISQEKENQLREMI 594

Query: 441  XXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKD 500
                    +A+ Q+E +++        +   +E +++ ++V ++  ++       + ++ 
Sbjct: 595  KVSDMKVKLAERQMEQKENEMKLLREEMVYLSEQLDQGSEVMKEYDRQC------IEIEM 648

Query: 501  LIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHK---LKLKQMQKTIDNFSKVSDSNKEI 557
            L ++    ++ I  L  +ID  N   ++++  ++   +  +++Q+T+     +    K+ 
Sbjct: 649  LTQQKDQLQQTIMILEKQIDEKNLEFMQLQQAYRDIEIDREKLQETVIKQESIIQEAKQ- 707

Query: 558  VRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIE-MENLAETRLKAI 616
               TE  +H+ ++  ++ E+   +       D   ++   V K+  E ++ L  TR +  
Sbjct: 708  ---TE--NHIREEKRKVIEQFKQVSYEKRISDEKALVTEVVEKQNEELLQKLDSTRNEMK 762

Query: 617  SLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKK 676
             LLE  + + +Q +  L ++ ++   ++ ++ + QS     + +    E +++      K
Sbjct: 763  QLLEQLRQEKLQ-VEKLTEENEKQNQRIKELEESQSVMRAIQSEKEKEESRLEVEMLKMK 821

Query: 677  ELALVIENLKLDKE--QLYGTIKDLENDKEDI---MNKLQNYIQENMDLTDKLEKMSAEK 731
              ++V  N + + E  QL   I++LE   ++    +N LQ  I+E       L K     
Sbjct: 822  HESMVSLNKQYEDEILQLSKDIQELEKSLKNSYKRINALQQEIEEKEQQISDLRKELDLV 881

Query: 732  ISELLAKINHEEQSKIQTQF-GIDAKIQE-RDL--YIENIESELSKYKSRICRLEESIAV 787
              +++ KINH E+S+ QTQ   +  ++++ R+L   I  ++S  +KY   I  L++ I  
Sbjct: 882  DRQVILKINH-EKSQYQTQVTDLQLEVEQMRNLQQQIALLKSNDAKYIETIASLQKEINK 940

Query: 788  MEDRRYSLERKADQLGSYLQEKQKAYSE-YTIQEDELVNRLAVLMDHDRVVEKQLLEIEH 846
            +E     L+ K  Q    LQ+ + A+++    Q  + V  L   + H +    Q+L  E 
Sbjct: 941  LEIDNQDLQFKIKQQDLQLQKTEIAFNQNIHYQASQHVIDLETQI-HQQQARNQIL--EQ 997

Query: 847  ENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESN 906
            + K + +K +   +  +   ++      +YN  V+K  +     +  T      R  + +
Sbjct: 998  QLKAMTEKYEQKAKLFERYGVNFDPQHPNYNQTVKKIPQ---PTNMLTSPPFSPRKNQVS 1054

Query: 907  LKRITHEHQTLIVQKKKEIEDLEIEFNTQ 935
               I++ +  L +   ++++   + FN Q
Sbjct: 1055 TASISNNNNPLFLSPPQKLQSQNLLFNQQ 1083


>UniRef50_Q52L24 Cluster: LOC733209 protein; n=1; Xenopus laevis|Rep:
            LOC733209 protein - Xenopus laevis (African clawed frog)
          Length = 1713

 Score =  126 bits (305), Expect = 4e-27
 Identities = 246/1317 (18%), Positives = 553/1317 (41%), Gaps = 129/1317 (9%)

Query: 309  EIEEKGSLEIANMTELTKKIE-LLEHLNCQIRQTNKELE-NKLATMGTESKAVSSPSKKG 366
            EI+EK  LEI       ++++  L++L   + +T +     ++A +  + +      +  
Sbjct: 414  EIQEKHELEIQEKCLTVQQLQHQLQNLGNNVGETAQPTNITEMAVVKLQDEVKLKTEESQ 473

Query: 367  SPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEY 426
                  +   N   +++    +L ++       + IN+  +AKL +  +   K   D E 
Sbjct: 474  GKNQDLRGLSNRIVELEEEKHELETKLKTLTELQAINEQLLAKLVLYEEQQRKLQADLEQ 533

Query: 427  VISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLK 486
            V    D+            + L+   ++  +   E P       ++E+ + +A    Q++
Sbjct: 534  VAKRADSQTSESGSVDELHNQLLEWNEMSPEME-EAPE-----NSSEEKSVLALRMAQIE 587

Query: 487  QELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLK---QMQKT 543
            +E   E  D   ++L E+L SA   + ++       +K   K++       K       T
Sbjct: 588  EER--EAMDSGQQELEEEL-SAARGLGKMRPARRKGSKAATKMQEEDDYSRKGFDDQNVT 644

Query: 544  IDNFSKVSDSNKEIVR-LTEEL----HHLSQKVAELE------EEKGNLQLHLVDYDS-G 591
            +D+       N   +R + EEL    + L +++  LE      E++  LQL +       
Sbjct: 645  LDSIDSAEGENMGGLRTVVEELELERNQLQEQIMSLEDRCQELEDRLQLQLRIESLQGEN 704

Query: 592  RMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVED-------KL 644
              +++ + +   +     E +    S L  Q          L+    E E        KL
Sbjct: 705  ERLQAQLGQLRQQQNRETEKQHSFTSTLSEQLKGFTDRNAFLENVIAEKEQIILEAAGKL 764

Query: 645  ADISQLQSDQVCSEIKSVHLEEQIDA----LSASKKELALV---IENLKLDKEQLY---G 694
             ++++L+      E  +  + E++D     L  + K+LA++    + LKL   +L     
Sbjct: 765  EELARLKKILKEKEDLNKAIAEKLDQSELQLEETSKKLAVLETESQALKLSNNELTEKAA 824

Query: 695  TIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGID 754
            T+K+    ++  + K+Q  +++  +  D+L     E+ S+L+  +   E+     +    
Sbjct: 825  TLKEKLLKQDAALEKMQLDLEQTNEELDRLNTSHLEERSQLIYDLQRCEREMDVLR---- 880

Query: 755  AKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYS 814
              +QE+D  + ++ S L++Y  ++  L+E I +  ++   +   +D L    +E Q    
Sbjct: 881  EVLQEKDKELASLSSSLTEYNEQVVILKEQIDLKNEQ---MREMSDALVKAERESQLLRE 937

Query: 815  EYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQ 874
              T    E+ ++++ L D    ++ +L + ++ ++   K+ + L+ +     I++ +++ 
Sbjct: 938  AQTSDTREMSDKISSLTDQLSEMDMELNKAKYLSETKAKEAEELIRQINENGITIKNLRS 997

Query: 875  HYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNT 934
               A  + A   + A   ST+  +  + + +++ ++  E +T   + +KEIE L+++  +
Sbjct: 998  EIQA--QSATHNNHAIECSTQITSLKQQINASVAKLD-ETET---KYRKEIESLKLQLES 1051

Query: 935  QIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDK--- 991
             +    +   +L EK  +   +  +L+   ++Y N +  ++   EE+ K+  E+ ++   
Sbjct: 1052 DVSEREKIAGLLAEKSSQERSFENELKVAKEQYNNLVSGISKKDEEIEKLLTEVAEQKKF 1111

Query: 992  --HVQKQ-QTQSPDYT---EQYINEINKLNALLKQKDEEIIALN-------QKINNAQVS 1038
              H++K+ Q +  D +   E+ + +I      L+   E   AL          IN +  +
Sbjct: 1112 CDHLRKELQIKEKDASSLQEKLLADIKDREEKLRGFQESTQALQAQLSEKLDNINKSDAT 1171

Query: 1039 YMSMVSDYESKLAQFTTKLENMEEEM---QRVSKQLLDSKQHNEELQILVREQDDQIKEL 1095
               +V   +      + K +N+E  +   +   K +L+ +QHN++   L+ E++   KEL
Sbjct: 1172 KNELVEQNKILKTALSEKDKNLEVHLTATEECRKSILELEQHNQQ---LLNEKEHLAKEL 1228

Query: 1096 KETK-----LTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQ--EEE 1148
             E K     L  E+NI +   + +   +E    D NN D            L+ Q  EE 
Sbjct: 1229 SEQKQFYDDLKKELNIKEENSLCLQQKLEM---DINNRDEKLTVLEERVLELQKQLDEEL 1285

Query: 1149 EFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNT 1208
            E I   +  +++  K N  L+    +  + + L+  L   +   ++ I  L+ + +QL +
Sbjct: 1286 ENIHNLNTAKDELDKRNKILEVALAE--REKNLSVHLNKTEEC-RKHILDLEQQKQQLYS 1342

Query: 1209 ENDNLLSTVAELRSSIS------SAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLS 1262
            E ++L+  +A+ +           A +Q+   + +  + HL  R+   +  +   +    
Sbjct: 1343 EKEHLVEELAKQKQCCDHLTAELQATEQKASTLQQKHEAHLKDRDELLRVLQESTQKLQK 1402

Query: 1263 AFESKYEQL--LDSVQSSTQEETNKIVTM-----EQVTSLQNKLQDKEEHLRNLQEKYAD 1315
              E K E +  LD+ ++   E+  K+ +      E +   QN  ++   ++ +L+++   
Sbjct: 1403 QLEEKVEHINTLDAAKNGLCEQNKKLESSLAEKNENLGVYQNSAEELRRNIVDLEQQKQQ 1462

Query: 1316 VINQIEILRSEI---EDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQM---QEQSILN 1369
            + ++ E +R E+   E   ++                  L  E +   Q+   +E+  L 
Sbjct: 1463 LHSEKEHIRQELSARESALLSLNQVLHDLQGKMSEMELLLMEEKKWVSQLTLDKEELQLK 1522

Query: 1370 IN-------EENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQL-----ELKDSE-- 1415
            I+       E +  + K              ++++ +     L +Q+     +LK+S+  
Sbjct: 1523 ISHMSEQSLERDTVISKQLEDKALESFSLKDQLSEEKQNAKNLLNQIHVQENQLKESQKR 1582

Query: 1416 IYQKTHEYTITLTQRNDEFENVRQ---QLVEYEKRIEDLTYEKESELAILRLKMHENANH 1472
            + Q   E  +   + N  FE+++Q   + VE +K +E+LT     E   L+ ++ +    
Sbjct: 1583 VQQSVEELELMKVEYNTIFESLKQNEERNVELQKHVEELTTALGRENQALKAELEQWKAS 1642

Query: 1473 YETMQKESEIERVKLIEELNVKITE-SVSLNKQVAELNKALEEEVAKTNEMQTALEN 1528
            +  +Q E  I R +  + ++++ITE S  L K   + ++  +E V KT E  + L++
Sbjct: 1643 FAALQNEENILREE-HKRVSLQITELSAELLKLNVDQDRLQQEAVQKTEENASLLKS 1698



 Score =  120 bits (290), Expect = 3e-25
 Identities = 257/1331 (19%), Positives = 547/1331 (41%), Gaps = 118/1331 (8%)

Query: 320  NMTELTKKIELLEHLNCQIRQTNKELENKLATM---------GTESKAVSSPSKKGSPLI 370
            ++ +LT+++   E L  Q+++  +E +N+L              ESK   +  +  + ++
Sbjct: 38   SVADLTEQLAQTEQLVVQLKELIREKDNELRKKDQQLKEKRESAESKISKAKLQNKAKIV 97

Query: 371  SRKSGRNTASKMKS---PWSQLS-SETLNQDTD---KKINKNEIAKLEMVIQSLNKDLVD 423
            S  S      K ++   P  + S ++  + D D      N+ +I  L+  ++ L   L  
Sbjct: 98   SLTSQLEELKKQQASSRPHEKKSENKKASGDGDYENSSANRGKILLLKRRVEELESQLAH 157

Query: 424  KEYVISEKDTXXXXXXXXXXGKDTLIAQLQ--LEHQQHMEGPSLIHVGTNTED--VNEIA 479
            K   + +K+             D ++++ +  L  ++       +  G+NT     +   
Sbjct: 158  KNEELQKKEADLEQQRLRGSQMDAMLSEKEQKLAAKEAYIIDLQMAAGSNTSKNVPSSQD 217

Query: 480  KVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQ 539
              QE  K + N E++ V +++L  K+  ++E+ + L ++ ++    + K K + K +   
Sbjct: 218  NTQETNKDKANQELQ-VLIQNLTRKVGESDEKCSLLQEQAESLKTLLNKEKDHFKAREAM 276

Query: 540  MQKTIDNFSK-VSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLH-LVDYDSGRMIESD 597
              + I  F   V +  KE+   +++  H       L +   N  LH L+     ++ E +
Sbjct: 277  YTENIRVFQNLVQEKEKELKEQSQK--HEQDIFKLLAKSDANADLHQLLKALKQKLHEEE 334

Query: 598  VYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCS 657
              + ++    + +   K +   E Q  ++ ++   LQ + + ++ KL     +   Q+  
Sbjct: 335  --EVLLGKNQVIDVLQKELDNKEQQNMEITEKCKRLQSEKENLQSKLEAEKHVMRAQL-R 391

Query: 658  EIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQEN 717
            ++   H  E          ++  + E  +L+ ++   T++ L++     +  L N + E 
Sbjct: 392  DMMDKHETELRGLHDKHVAQIQEIQEKHELEIQEKCLTVQQLQHQ----LQNLGNNVGET 447

Query: 718  MDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSR 777
               T+ + +M+  K+ + +     E Q K Q   G+  +I E       +E E  + +++
Sbjct: 448  AQPTN-ITEMAVVKLQDEVKLKTEESQGKNQDLRGLSNRIVE-------LEEEKHELETK 499

Query: 778  ICRLEESIAVMEDRRYSL---ERKADQLGSYLQEKQKAYSEYTIQE---DELVNRLAVLM 831
            +  L E  A+ E     L   E +  +L + L++  K     T +    DEL N+L    
Sbjct: 500  LKTLTELQAINEQLLAKLVLYEEQQRKLQADLEQVAKRADSQTSESGSVDELHNQLLEWN 559

Query: 832  DHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAES 891
            +    +E+       E   L  +   + EE + +     ++++  +A      +   A  
Sbjct: 560  EMSPEMEEAPENSSEEKSVLALRMAQIEEEREAMDSGQQELEEELSA-ARGLGKMRPARR 618

Query: 892  ESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYE 951
            + +K  T++++ E +  R   + Q + +     I+  E E    + + + + ++   + +
Sbjct: 619  KGSKAATKMQE-EDDYSRKGFDDQNVTLD---SIDSAEGENMGGLRTVVEELELERNQLQ 674

Query: 952  KNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEI 1011
               E +  LE + QE ++ ++ L + +E L   N  L  +  Q +Q Q+ + TE+  +  
Sbjct: 675  ---EQIMSLEDRCQELEDRLQ-LQLRIESLQGENERLQAQLGQLRQQQNRE-TEKQHSFT 729

Query: 1012 NKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQL 1071
            + L+  LK   +    L   I   +   +      E +LA+    L+  E+  + ++++L
Sbjct: 730  STLSEQLKGFTDRNAFLENVIAEKEQIILEAAGKLE-ELARLKKILKEKEDLNKAIAEKL 788

Query: 1072 LDSKQHNEEL--QILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVD 1129
              S+   EE   ++ V E + Q  +L   +LT +    K + +   + +E M  D    +
Sbjct: 789  DQSELQLEETSKKLAVLETESQALKLSNNELTEKAATLKEKLLKQDAALEKMQLDLEQTN 848

Query: 1130 XXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHD 1189
                          ++E  + I +    + +   L   LQE   ++  L +  TE     
Sbjct: 849  EELDRLNTS----HLEERSQLIYDLQRCEREMDVLREVLQEKDKELASLSSSLTEYNEQV 904

Query: 1190 VVNQEQINQLKSKLEQLN-----TENDNLL------STVAELRSSISSAVDQRGFEIAEL 1238
            V+ +EQI+    ++ +++      E ++ L      S   E+   ISS  DQ      EL
Sbjct: 905  VILKEQIDLKNEQMREMSDALVKAERESQLLREAQTSDTREMSDKISSLTDQLSEMDMEL 964

Query: 1239 WK-QHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTME-QVTSLQ 1296
             K ++L++ +A   K   EL  Q++      + L   +Q+ +    N  +    Q+TSL+
Sbjct: 965  NKAKYLSETKA---KEAEELIRQINENGITIKNLRSEIQAQSATHNNHAIECSTQITSLK 1021

Query: 1297 NKLQDKEEHLRNLQEKYADVINQIEI-LRSEI-EDEKVAFXXXXXXXXXXXXXXXXDLRT 1354
             ++      L   + KY   I  +++ L S++ E EK+A                 +L+ 
Sbjct: 1022 QQINASVAKLDETETKYRKEIESLKLQLESDVSEREKIA--GLLAEKSSQERSFENELKV 1079

Query: 1355 ENQSYKQM------QEQSILNINEENAQLKK-----------SSXXXXXXXXXXXXRVND 1397
              + Y  +      +++ I  +  E A+ KK                          + D
Sbjct: 1080 AKEQYNNLVSGISKKDEEIEKLLTEVAEQKKFCDHLRKELQIKEKDASSLQEKLLADIKD 1139

Query: 1398 AEAKV---LELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIE-DLTY 1453
             E K+    E T  L+ + SE     ++   T  +  ++ + ++  L E +K +E  LT 
Sbjct: 1140 REEKLRGFQESTQALQAQLSEKLDNINKSDATKNELVEQNKILKTALSEKDKNLEVHLTA 1199

Query: 1454 EKESELAILRLKMHEN--ANHYETMQKE-SEIERV--KLIEELNVKITESVSLNKQVAEL 1508
             +E   +IL L+ H     N  E + KE SE ++    L +ELN+K   S+ L ++    
Sbjct: 1200 TEECRKSILELEQHNQQLLNEKEHLAKELSEQKQFYDDLKKELNIKEENSLCLQQK---- 1255

Query: 1509 NKALEEEVAKTNEMQTALENQEIEI-VTLNDEITNLQNMVRASSSKIQKHVSFASDTKQG 1567
               LE ++   +E  T LE + +E+   L++E+ N+ N+   +  ++ K           
Sbjct: 1256 ---LEMDINNRDEKLTVLEERVLELQKQLDEELENIHNL-NTAKDELDKRNKILEVALAE 1311

Query: 1568 RDEQLDNTMNK 1578
            R++ L   +NK
Sbjct: 1312 REKNLSVHLNK 1322



 Score =  119 bits (287), Expect = 6e-25
 Identities = 223/1140 (19%), Positives = 478/1140 (41%), Gaps = 123/1140 (10%)

Query: 469  GTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIK 528
            G + + V +I ++QE  K EL  + K + V+ L  +L++    + +     +     ++K
Sbjct: 403  GLHDKHVAQIQEIQE--KHELEIQEKCLTVQQLQHQLQNLGNNVGETAQPTNITEMAVVK 460

Query: 529  VKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDY 588
            ++   KLK ++ Q                    ++L  LS ++ ELEEEK  L+  L   
Sbjct: 461  LQDEVKLKTEESQGK-----------------NQDLRGLSNRIVELEEEKHELETKL--- 500

Query: 589  DSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADIS 648
                       K + E++ + E  L  + L E Q+  L  +L  + ++ D    +   + 
Sbjct: 501  -----------KTLTELQAINEQLLAKLVLYEEQQRKLQADLEQVAKRADSQTSESGSVD 549

Query: 649  QLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDI-- 706
            +L +  +     S  +EE  +  S  K  LAL +  ++ ++E +    ++LE +      
Sbjct: 550  ELHNQLLEWNEMSPEMEEAPENSSEEKSVLALRMAQIEEEREAMDSGQQELEEELSAARG 609

Query: 707  MNKLQNYIQENMDLTDKLEK---MSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLY 763
            + K++   ++      K+++    S +   +    ++  + ++ +   G+   ++E +L 
Sbjct: 610  LGKMRPARRKGSKAATKMQEEDDYSRKGFDDQNVTLDSIDSAEGENMGGLRTVVEELELE 669

Query: 764  IENIESELSKYKSRICRLEESIAV---MEDRRYSLERKADQLGSYLQEKQKAYSEYTIQE 820
               ++ ++   + R   LE+ + +   +E  +   ER   QLG   Q++ +   +     
Sbjct: 670  RNQLQEQIMSLEDRCQELEDRLQLQLRIESLQGENERLQAQLGQLRQQQNRETEKQHSFT 729

Query: 821  DELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALV 880
              L  +L    D +  +E  + E E    E   K    LEE   L+  L + +    A+ 
Sbjct: 730  STLSEQLKGFTDRNAFLENVIAEKEQIILEAAGK----LEELARLKKILKEKEDLNKAIA 785

Query: 881  EKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAI 940
            EK ++++L   E++K    L      LK   +E    + +K   +++  ++ +  +E   
Sbjct: 786  EKLDQSELQLEETSKKLAVLETESQALKLSNNE----LTEKAATLKEKLLKQDAALEKMQ 841

Query: 941  RDKKVLNEKYEK----NIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQ 996
             D +  NE+ ++    ++E  +QL   LQ  +  ++ L   ++E         DK +   
Sbjct: 842  LDLEQTNEELDRLNTSHLEERSQLIYDLQRCEREMDVLREVLQEK--------DKELASL 893

Query: 997  QTQSPDYTEQYI---NEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQF 1053
             +   +Y EQ +    +I+  N  +++  + ++   ++    + +  S   +   K++  
Sbjct: 894  SSSLTEYNEQVVILKEQIDLKNEQMREMSDALVKAERESQLLREAQTSDTREMSDKISSL 953

Query: 1054 TTKLENMEEEMQRVSKQLLDSK-QHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGM 1112
            T +L  M+ E+ + +K L ++K +  EEL   + E    IK L+ +++  +        +
Sbjct: 954  TDQLSEMDMELNK-AKYLSETKAKEAEELIRQINENGITIKNLR-SEIQAQSATHNNHAI 1011

Query: 1113 IISSTIEPMSDDAN----NVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTEL 1168
              S+ I  +    N     +D            LK+Q E + + ER    E+ A L  E 
Sbjct: 1012 ECSTQITSLKQQINASVAKLDETETKYRKEIESLKLQLESD-VSER----EKIAGLLAE- 1065

Query: 1169 QECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAV 1228
                 K  Q  +   EL     V +EQ N L S + + + E + LL+ VAE +       
Sbjct: 1066 -----KSSQERSFENELK----VAKEQYNNLVSGISKKDEEIEKLLTEVAEQKKFCDHL- 1115

Query: 1229 DQRGFEIAELWKQHLAQR-EADFQKTEHELR---VQLSAFESKYEQLLDSVQSSTQEETN 1284
             ++  +I E     L ++  AD +  E +LR       A +++  + LD++  S   + N
Sbjct: 1116 -RKELQIKEKDASSLQEKLLADIKDREEKLRGFQESTQALQAQLSEKLDNINKSDATK-N 1173

Query: 1285 KIVTMEQV--TSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXX 1342
            ++V   ++  T+L  K ++ E HL   +E    ++ ++E    ++ +EK           
Sbjct: 1174 ELVEQNKILKTALSEKDKNLEVHLTATEECRKSIL-ELEQHNQQLLNEKEHLAKELSEQK 1232

Query: 1343 XXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKV 1402
                    +L  + ++   +Q++  ++IN  + +L                +  D E   
Sbjct: 1233 QFYDDLKKELNIKEENSLCLQQKLEMDINNRDEKL-----TVLEERVLELQKQLDEE--- 1284

Query: 1403 LELTHQLELKDSEIYQKTHEYTITLTQRN-------DEFENVRQQLVEYEKRIEDLTYEK 1455
            LE  H L     E+ ++     + L +R        ++ E  R+ +++ E++ + L  EK
Sbjct: 1285 LENIHNLNTAKDELDKRNKILEVALAEREKNLSVHLNKTEECRKHILDLEQQKQQLYSEK 1344

Query: 1456 ESELAILRLKMHENANHY--ETMQKESEIERVKLIEELNVKITESV--SLNKQVAELNKA 1511
            E  +  L  K  +  +H   E    E +   ++   E ++K  + +   L +   +L K 
Sbjct: 1345 EHLVEEL-AKQKQCCDHLTAELQATEQKASTLQQKHEAHLKDRDELLRVLQESTQKLQKQ 1403

Query: 1512 LEEEVAKTNEMQTAL-----ENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQ 1566
            LEE+V   N +  A      +N+++E  +L ++  NL  + + S+ ++++++      KQ
Sbjct: 1404 LEEKVEHINTLDAAKNGLCEQNKKLE-SSLAEKNENL-GVYQNSAEELRRNIVDLEQQKQ 1461



 Score =  105 bits (252), Expect = 1e-20
 Identities = 184/956 (19%), Positives = 415/956 (43%), Gaps = 82/956 (8%)

Query: 310  IEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPL 369
            I EK       + E +KK+ +LE  +  ++ +N EL  K AT+  + K +   +      
Sbjct: 784  IAEKLDQSELQLEETSKKLAVLETESQALKLSNNELTEKAATL--KEKLLKQDAALEKMQ 841

Query: 370  ISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVIS 429
            +  +       ++ +   +  S+ +    D +  + E+  L  V+Q  +K+L      ++
Sbjct: 842  LDLEQTNEELDRLNTSHLEERSQLI---YDLQRCEREMDVLREVLQEKDKELASLSSSLT 898

Query: 430  EKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQEL 489
            E +            K+  + ++  +     E  S +     T D  E++     L  +L
Sbjct: 899  EYNEQVVILKEQIDLKNEQMREMS-DALVKAERESQLLREAQTSDTREMSDKISSLTDQL 957

Query: 490  NDEIKDVN-VKDLIE-KLKSAEEQITQLNDE-IDAAN-KNMIKVKS----NHKL----KL 537
            ++   ++N  K L E K K AEE I Q+N+  I   N ++ I+ +S    NH +    ++
Sbjct: 958  SEMDMELNKAKYLSETKAKEAEELIRQINENGITIKNLRSEIQAQSATHNNHAIECSTQI 1017

Query: 538  KQMQKTID-NFSKVSDSNKEIVRLTEELH-HLSQKVAELEEEKGNL---QLHLVDYDSGR 592
              +++ I+ + +K+ ++  +  +  E L   L   V+E E+  G L         +++  
Sbjct: 1018 TSLKQQINASVAKLDETETKYRKEIESLKLQLESDVSEREKIAGLLAEKSSQERSFENEL 1077

Query: 593  MIESDVYKKMIEMENLAETRLKAI--SLLESQKF--DLVQELHILQQKYDEVEDK-LADI 647
             +  + Y  ++   +  +  ++ +   + E +KF   L +EL I ++    +++K LADI
Sbjct: 1078 KVAKEQYNNLVSGISKKDEEIEKLLTEVAEQKKFCDHLRKELQIKEKDASSLQEKLLADI 1137

Query: 648  ----SQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLE--- 700
                 +L+  Q  ++     L E++D ++ S      ++E  K+ K  L    K+LE   
Sbjct: 1138 KDREEKLRGFQESTQALQAQLSEKLDNINKSDATKNELVEQNKILKTALSEKDKNLEVHL 1197

Query: 701  NDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQER 760
               E+    +    Q N  L ++ E ++ E   +     + +++  I+ +  +  + Q+ 
Sbjct: 1198 TATEECRKSILELEQHNQQLLNEKEHLAKELSEQKQFYDDLKKELNIKEENSLCLQ-QKL 1256

Query: 761  DLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQE 820
            ++ I N + +L+  + R+  L++ +    +  ++L    D+L     +K+    E  + E
Sbjct: 1257 EMDINNRDEKLTVLEERVLELQKQLDEELENIHNLNTAKDEL-----DKRNKILEVALAE 1311

Query: 821  DELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALV 880
             E    L+V ++      K +L++E + ++L  + + L+EE       L+  +Q  + L 
Sbjct: 1312 RE--KNLSVHLNKTEECRKHILDLEQQKQQLYSEKEHLVEE-------LAKQKQCCDHLT 1362

Query: 881  EKANRTD-LAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESA 939
             +   T+  A +   K++  L+D +  L+ +    Q L    +K++E+ ++E    +++A
Sbjct: 1363 AELQATEQKASTLQQKHEAHLKDRDELLRVLQESTQKL----QKQLEE-KVEHINTLDAA 1417

Query: 940  IRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLEL-IDKHVQKQQT 998
               K  L E+ +K    + +    L  Y+N+ E L  N+ +L +   +L  +K   +Q+ 
Sbjct: 1418 ---KNGLCEQNKKLESSLAEKNENLGVYQNSAEELRRNIVDLEQQKQQLHSEKEHIRQEL 1474

Query: 999  QSPDYTEQYINEI--------NKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKL 1050
             + +     +N++        +++  LL ++ + +  L       Q+    M      + 
Sbjct: 1475 SARESALLSLNQVLHDLQGKMSEMELLLMEEKKWVSQLTLDKEELQLKISHMSEQSLERD 1534

Query: 1051 AQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKE--TKLTFEMNIPK 1108
               + +LE+   E   +  QL + KQ+ + L   +  Q++Q+KE ++   +   E+ + K
Sbjct: 1535 TVISKQLEDKALESFSLKDQLSEEKQNAKNLLNQIHVQENQLKESQKRVQQSVEELELMK 1594

Query: 1109 TEGMIISSTIEPMSDDAN-----NVDXXXXXXXXXXXXLKVQEEE------EFIQERSVL 1157
             E   I  +++  +++ N     +V+            LK + E+          E ++L
Sbjct: 1595 VEYNTIFESLK-QNEERNVELQKHVEELTTALGRENQALKAELEQWKASFAALQNEENIL 1653

Query: 1158 QEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNL 1213
            +E+  +++ ++ E   ++++L      L    V   E+   L   L+ +N   D L
Sbjct: 1654 REEHKRVSLQITELSAELLKLNVDQDRLQQEAVQKTEENASLLKSLDSINVVADTL 1709



 Score = 77.0 bits (181), Expect = 4e-12
 Identities = 160/850 (18%), Positives = 345/850 (40%), Gaps = 66/850 (7%)

Query: 90   ISESLANTLKQKEILMEKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSN 149
            +S SL    +Q  IL E+I    E  +  S  +V+               Q  D   +S+
Sbjct: 893  LSSSLTEYNEQVVILKEQIDLKNEQMREMSDALVKAERESQLLREA----QTSDTREMSD 948

Query: 150  TIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXX 209
             I    + LS  ++ M++ +   L  + K  E +++I   N+                  
Sbjct: 949  KISSLTDQLS--EMDMELNKAKYLS-ETKAKEAEELIRQINENGITIKNLRSEIQAQSAT 1005

Query: 210  XXE---DTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFE 266
                  +   Q+T +++   A  A+  + + +  K+IES  +++ S     + +     E
Sbjct: 1006 HNNHAIECSTQITSLKQQINASVAKLDETETKYRKEIESLKLQLESDVSEREKIAGLLAE 1065

Query: 267  ISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTK 326
             S +      EL+               ++K+  E   +  TE+ E+         EL  
Sbjct: 1066 KSSQERSFENELK---VAKEQYNNLVSGISKKDEEIE-KLLTEVAEQKKFCDHLRKELQI 1121

Query: 327  KIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPW 386
            K +    L  ++    K+ E KL      ++A+ +   +    I++     T +++    
Sbjct: 1122 KEKDASSLQEKLLADIKDREEKLRGFQESTQALQAQLSEKLDNINKSDA--TKNELVEQN 1179

Query: 387  SQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKD 446
              L +    +D + +++     +    I  L +     + +++EK+             D
Sbjct: 1180 KILKTALSEKDKNLEVHLTATEECRKSILELEQ---HNQQLLNEKEHLAKELSEQKQFYD 1236

Query: 447  TLIAQLQLEHQQHMEGPSLIHVGTNTED------VNEIAKVQEQLKQELNDEIKDVN-VK 499
             L  +L ++ +  +     + +  N  D         + ++Q+QL +EL + I ++N  K
Sbjct: 1237 DLKKELNIKEENSLCLQQKLEMDINNRDEKLTVLEERVLELQKQLDEEL-ENIHNLNTAK 1295

Query: 500  DLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVR 559
            D ++K     E      ++  + + N  +    H L L+Q ++ +  +S+     +E+ +
Sbjct: 1296 DELDKRNKILEVALAEREKNLSVHLNKTEECRKHILDLEQQKQQL--YSEKEHLVEELAK 1353

Query: 560  LTEELHHLSQKVAELEEEKGNLQ----LHLVDYDS-GRMIESDVYKKMIEMENLAETRLK 614
              +   HL+ ++   E++   LQ     HL D D   R+++    K    ++   E +++
Sbjct: 1354 QKQCCDHLTAELQATEQKASTLQQKHEAHLKDRDELLRVLQESTQK----LQKQLEEKVE 1409

Query: 615  AISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSAS 674
             I+ L++ K  L ++   L+    E  + L  + Q  ++++   I  V LE+Q   L + 
Sbjct: 1410 HINTLDAAKNGLCEQNKKLESSLAEKNENLG-VYQNSAEELRRNI--VDLEQQKQQLHSE 1466

Query: 675  KKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISE 734
            K+ +   +      +E    ++  + +D +  M++++  + E      +L   + +K  E
Sbjct: 1467 KEHIRQELS----ARESALLSLNQVLHDLQGKMSEMELLLMEEKKWVSQL---TLDK-EE 1518

Query: 735  LLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYS 794
            L  KI+H  +  ++    I  +++++ L   +++ +LS+ K     L   I V E++   
Sbjct: 1519 LQLKISHMSEQSLERDTVISKQLEDKALESFSLKDQLSEEKQNAKNLLNQIHVQENQLKE 1578

Query: 795  LERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKK 854
             +++  Q    L+  +  Y+  TI E       ++  + +R VE Q   +E     L ++
Sbjct: 1579 SQKRVQQSVEELELMKVEYN--TIFE-------SLKQNEERNVELQ-KHVEELTTALGRE 1628

Query: 855  NQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEH 914
            NQ L  E +  + S + +Q   N L E+  R  L   + T+   +L  L  +  R+  E 
Sbjct: 1629 NQALKAELEQWKASFAALQNEENILREEHKRVSL---QITELSAELLKLNVDQDRLQQE- 1684

Query: 915  QTLIVQKKKE 924
                VQK +E
Sbjct: 1685 ---AVQKTEE 1691


>UniRef50_Q7NBF8 Cluster: Putative uncharacterized protein; n=1;
            Mycoplasma gallisepticum|Rep: Putative uncharacterized
            protein - Mycoplasma gallisepticum
          Length = 1931

 Score =  126 bits (305), Expect = 4e-27
 Identities = 231/1182 (19%), Positives = 500/1182 (42%), Gaps = 115/1182 (9%)

Query: 233  KDEKQRLLKDIESKDVRI-SSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXX 291
            K+E ++  ++   + ++I  S   A++     + E+   + K    + +           
Sbjct: 319  KNEVEKAKQNFNDQQLKILQSKANADQYFALRKIELENSYKKAKNAILEANKAHAKNVQE 378

Query: 292  XXXLAKQSIEPSCEEKTEIEEKGSLEIANMT-ELTKKIEL--LEHLNCQIRQTNKELENK 348
               LA ++ +         E+   L+IA+++ E  +K  L  L +L  +++Q +  LE K
Sbjct: 379  EQALANKNNKTQRLLNKLKEDYDRLKIASLSFESMRKQSLAALNNLQDELKQKHNLLERK 438

Query: 349  LATM-GTESKAVSSPSKKGSPLISRK-----SGRNTASKMKSPWSQLSSETLNQDT---D 399
                 G  ++ +S      S L+ +K        N   + K+  + L+ +    D    +
Sbjct: 439  KHEQDGIVNEKISELEGYRSDLVDQKLKIEREKENQERRYKAAEASLNKKRQEIDELFLE 498

Query: 400  KKINKNEIAKLEMVIQSLNKDLVDK----EYVISEKDTXXXXXXXXXXGKDTLIAQLQLE 455
                 NE +  E  + +  ++++ K    E++ SE D                I ++QL+
Sbjct: 499  ANTKLNEASLKENDLNNQKREILAKLRNLEHLKSEIDQRRRDLDQRELIDQQTIRKIQLD 558

Query: 456  HQQH---MEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVN--VKDLIEK---LKS 507
             +     ++   LI    N E   E+ + +  +K++  D    VN   K L ++   LK 
Sbjct: 559  VESERADLQRILLIERKKNDERQQELLQYERDIKRQQTDFENTVNWEQKKLSQREKELKD 618

Query: 508  AEEQI----TQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEE 563
              EQ+    +++ ++ID  N+ + + + + +  L   QK   +   ++ S   + +  EE
Sbjct: 619  GYEQLQLKQSEVQEKIDELNEEINRAQKSKQNSLVLEQKLKSDLEHLNLSKNYLDKQQEE 678

Query: 564  LHHLSQKVAELEEEKGNLQLHLVDYDSGRMIES-DVYKKMIEMENLAETRLKA-ISLLES 621
            L+  S K+ E         L + + D  R  E   +Y+K ++ +  +    +  +++ ++
Sbjct: 679  LNQKSDKMIE--------DLKVFERDLKRQKEDLSIYEKSLQQKEASLINFQNDVTVQKN 730

Query: 622  QKFDLVQELHI-LQQKYDEVEDKL----ADISQLQSDQVCSEIKSVHLEEQIDALSASKK 676
            + +   Q +H  L+ K   +E++L    A+   + +D+  +      ++E+I +L+  +K
Sbjct: 731  EAYHKAQAIHQELELKKAAIENELRKLTAERKAVDADKEENTKLKKFIDEEIRSLANERK 790

Query: 677  ELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISEL- 735
            EL +   N++  K      +  LE+D     N+L+   +E     ++L      ++ EL 
Sbjct: 791  ELEIYQNNIENFKNNAVDRLNVLESDLVKKRNELEQLKKEQQTHYNELNSNLTNELQELE 850

Query: 736  --LAKINHEEQSK----IQTQFGIDAKIQERDLYIENIESELSKYK----SRICRLEESI 785
                K  H++Q K    +Q +  +  K  E  LY + +    ++ K    S   + E   
Sbjct: 851  EQKKKFAHQKQQKFEELLQAKNNLSIKENELVLYAQKVNDRYNELKAIEKSNTAKSEMIN 910

Query: 786  AVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIE 845
            A +E+ +++     +      QE+ K  ++  I E +   R  +L+  +  ++++  E +
Sbjct: 911  AKLEEFKHAEIDYLNYQNKIKQEQIKFDNQVKILESQYNQRNEILLIREEQIKQKKAEQQ 970

Query: 846  HENKELQKKNQILLEENQNL----QISLSDMQQHYNALVEKANRTDLAES--ESTKYQTQ 899
             + K++QK  + L EE  N     +   + +   Y  + ++ +  DLA+   E  K +  
Sbjct: 971  AQEKQIQKDFKRLQEEKNNFDDQKRNKFNKISNLYLEIKKQRDEVDLAQRQIEDQKEELL 1030

Query: 900  LRDLESNLKRITHEHQTLIVQK-------------KKEIEDLE------IEFNTQIESAI 940
            ++  E  L++   E +  +++K             KK I+ +E       + N + E   
Sbjct: 1031 IKAREGRLQKQEIEDRLAVLEKSEKRFRQEDELLAKKRIDLIERIGVLKADINKKHEILS 1090

Query: 941  RDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVE-ELNKMNLELIDKHVQKQQTQ 999
                 L EK +K  E    L+ +    ++ +E  N   + E  K+ +E  DK   +++  
Sbjct: 1091 LRSVQLTEKAKKQQEKDADLQRKFDLLESEVERFNEEKKSEFQKLKVER-DKLAHREKNV 1149

Query: 1000 SPDYTEQYINEINKLNALLKQKDEEIIALNQKIN--NAQVSYMSMVSDY-ESKLAQFTTK 1056
            S +  E  +  + KL+ + K    +   +N+K+   N Q   +   +D  ++K  +  T+
Sbjct: 1150 SKNMNEINL-ALAKLDLIRKNNKVDKAKINEKLALLNDQKEKIDRENDLLDAKKTEVITR 1208

Query: 1057 LENMEEEMQRVSKQLLDSKQHNEEL----QILVREQDDQIKELKETKLTFEMNIPKTEGM 1112
            L  ME +++   +++L  + + E +    Q L RE + + + L+  K +F          
Sbjct: 1209 LRKMENDLEFEKQKVLLDRSNIERISSDQQALARELETKYQTLEREKRSFSQRK------ 1262

Query: 1113 IISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECY 1172
               + ++ + D    V             LK+   E+  Q R +L+++S  +N   ++  
Sbjct: 1263 --ENELKEIDDFYQQVQHKERTLN-----LKI---EDLKQLRYLLEKESYNVNVNKKDLK 1312

Query: 1173 TKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAV--DQ 1230
             +I   + L   +         Q N   +K+E LN + +   S +A LRS I +     Q
Sbjct: 1313 VRIEHYQRLERAIKNEQHKLNNQKNNFFNKVELLNDQLNKKSSKIALLRSKIYNTYKQQQ 1372

Query: 1231 RGFEIAELWKQHLAQREADFQKTEHEL---RVQLSAFESKYEQLLDSVQSSTQEETNKIV 1287
            +  +I    K   +Q      KT+ EL   + Q S  + + E+ L + +   Q   ++++
Sbjct: 1373 QQKQILLEEKHKNSQLRKSLLKTQEELHQQKAQFSIAKKQEEKKLKNQKDLIQNTLSEVI 1432

Query: 1288 TM-EQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIE 1328
               +Q+T+++ ++  K+  L NL++    +I Q   L+ E+E
Sbjct: 1433 KQKDQITNIKQEVDLKQTQLNNLEKL---IIKQRADLQKELE 1471



 Score =  123 bits (296), Expect = 5e-26
 Identities = 229/1151 (19%), Positives = 491/1151 (42%), Gaps = 107/1151 (9%)

Query: 494  KDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDS 553
            K+   + L+ KLK   +++   +   ++  K  +   +N + +LKQ    ++      D 
Sbjct: 385  KNNKTQRLLNKLKEDYDRLKIASLSFESMRKQSLAALNNLQDELKQKHNLLERKKHEQDG 444

Query: 554  --NKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENL--- 608
              N++I  L      L  +  ++E EK N +         +  E+ + KK  E++ L   
Sbjct: 445  IVNEKISELEGYRSDLVDQKLKIEREKENQERRY------KAAEASLNKKRQEIDELFLE 498

Query: 609  AETRLKAISL----LESQKFDLVQELHILQQKYDEVEDKLADISQLQS-DQVCSEIKSVH 663
            A T+L   SL    L +QK +++ +L  L+    E++ +  D+ Q +  DQ    I+ + 
Sbjct: 499  ANTKLNEASLKENDLNNQKREILAKLRNLEHLKSEIDQRRRDLDQRELIDQ--QTIRKIQ 556

Query: 664  LEEQIDALSASKKELALVIENLKLDKEQ-----LYGTIKDLENDKEDIMNKLQNYI-QEN 717
            L+ + +     +    L+IE  K D+ Q         IK  + D E+ +N  Q  + Q  
Sbjct: 557  LDVESERADLQR---ILLIERKKNDERQQELLQYERDIKRQQTDFENTVNWEQKKLSQRE 613

Query: 718  MDLTDKLEKMSA------EKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESEL 771
             +L D  E++        EKI EL  +IN  ++SK Q    ++ K++    ++   ++ L
Sbjct: 614  KELKDGYEQLQLKQSEVQEKIDELNEEINRAQKSK-QNSLVLEQKLKSDLEHLNLSKNYL 672

Query: 772  SKYKSRICRLEESIAVMEDRRY---SLERKADQLGSY---LQEKQKAY----SEYTIQED 821
             K +  +   ++S  ++ED +     L+R+ + L  Y   LQ+K+ +     ++ T+Q++
Sbjct: 673  DKQQEELN--QKSDKMIEDLKVFERDLKRQKEDLSIYEKSLQQKEASLINFQNDVTVQKN 730

Query: 822  ELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQIL-LEENQNLQISLSDMQQHYNALV 880
            E  ++   +  H  + E +   IE+E ++L  + + +  ++ +N ++    + +   +L 
Sbjct: 731  EAYHKAQAI--HQEL-ELKKAAIENELRKLTAERKAVDADKEENTKLK-KFIDEEIRSLA 786

Query: 881  EKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAI 940
             +    ++       YQ  + + ++N     +  ++ +V+K+ E+E L+ E  T      
Sbjct: 787  NERKELEI-------YQNNIENFKNNAVDRLNVLESDLVKKRNELEQLKKEQQTHYNELN 839

Query: 941  RD-KKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQ 999
             +    L E  E+  ++  Q + + +E      NL++   EL     ++ D++ + +  +
Sbjct: 840  SNLTNELQELEEQKKKFAHQKQQKFEELLQAKNNLSIKENELVLYAQKVNDRYNELKAIE 899

Query: 1000 SPDYTEQYINEINKLNALLKQ-KDEEIIALN--QKINNAQVSYMSMVSDYESKLAQFTTK 1056
              +  +  +     +NA L++ K  EI  LN   KI   Q+ + + V   ES+  Q    
Sbjct: 900  KSNTAKSEM-----INAKLEEFKHAEIDYLNYQNKIKQEQIKFDNQVKILESQYNQRNEI 954

Query: 1057 LENMEEEM-QRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIIS 1115
            L   EE++ Q+ ++Q    KQ  ++ + L +E+ +   + K  K     N+     + I 
Sbjct: 955  LLIREEQIKQKKAEQQAQEKQIQKDFKRL-QEEKNNFDDQKRNKFNKISNLY----LEIK 1009

Query: 1116 STIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTK- 1174
               + +      ++             ++Q++E  I++R  + E+S K   +  E   K 
Sbjct: 1010 KQRDEVDLAQRQIEDQKEELLIKAREGRLQKQE--IEDRLAVLEKSEKRFRQEDELLAKK 1067

Query: 1175 ----IIQLETLNTELTG-HDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVD 1229
                I ++  L  ++   H++++   + QL  K ++   ++ +L      L S +    +
Sbjct: 1068 RIDLIERIGVLKADINKKHEILSLRSV-QLTEKAKKQQEKDADLQRKFDLLESEVERFNE 1126

Query: 1230 QRGFEIAELW--KQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIV 1287
            ++  E  +L   +  LA RE +  K  +E+ + L+         LD ++ + + +  KI 
Sbjct: 1127 EKKSEFQKLKVERDKLAHREKNVSKNMNEINLALAK--------LDLIRKNNKVDKAKIN 1178

Query: 1288 TMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXX 1347
                + + Q +  D+E  L  L  K  +VI ++  + +++E EK                
Sbjct: 1179 EKLALLNDQKEKIDRENDL--LDAKKTEVITRLRKMENDLEFEKQKVLLDRSNIERISSD 1236

Query: 1348 XXXDLRTENQSYKQMQ-EQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELT 1406
                 R     Y+ ++ E+   +  +EN   +                +   + K L   
Sbjct: 1237 QQALARELETKYQTLEREKRSFSQRKENELKEIDDFYQQVQHKERTLNLKIEDLKQLRYL 1296

Query: 1407 HQLELKDSEIYQKTHEYTITLTQR-----NDEFENVRQQLVEYEKRIE---DLTYEKESE 1458
             + E  +  + +K  +  I   QR      +E   +  Q   +  ++E   D   +K S+
Sbjct: 1297 LEKESYNVNVNKKDLKVRIEHYQRLERAIKNEQHKLNNQKNNFFNKVELLNDQLNKKSSK 1356

Query: 1459 LAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVS-LNKQVAELNKALEEEVA 1517
            +A+LR K++ N    +  QK+  +E      +L   + ++   L++Q A+ + A ++E  
Sbjct: 1357 IALLRSKIY-NTYKQQQQQKQILLEEKHKNSQLRKSLLKTQEELHQQKAQFSIAKKQEEK 1415

Query: 1518 KTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMN 1577
            K    +  ++N   E++   D+ITN++  V    +++          KQ  D Q +   N
Sbjct: 1416 KLKNQKDLIQNTLSEVIKQKDQITNIKQEVDLKQTQLNNLEKLI--IKQRADLQKELEKN 1473

Query: 1578 KELLDAVPRAE 1588
             E    + +AE
Sbjct: 1474 SENTYRLQKAE 1484



 Score =  116 bits (280), Expect = 4e-24
 Identities = 243/1276 (19%), Positives = 526/1276 (41%), Gaps = 96/1276 (7%)

Query: 147  LSNTIKEKDNALSVLQVKMKIMETTILDLQEKIN------EKDQIIEAKNKATTXXXXXX 200
            LS   KE  +    LQ+K   ++  I +L E+IN      +   ++E K K+        
Sbjct: 609  LSQREKELKDGYEQLQLKQSEVQEKIDELNEEINRAQKSKQNSLVLEQKLKS---DLEHL 665

Query: 201  XXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLL 260
                       E+  Q+  KM E+    E + K +K+ L    +S   + +SL      +
Sbjct: 666  NLSKNYLDKQQEELNQKSDKMIEDLKVFERDLKRQKEDLSIYEKSLQQKEASLINFQNDV 725

Query: 261  EAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIAN 320
               + E   +   + QELE                 +++++   EE T++++    EI +
Sbjct: 726  TVQKNEAYHKAQAIHQELE-LKKAAIENELRKLTAERKAVDADKEENTKLKKFIDEEIRS 784

Query: 321  MTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTAS 380
            +    K++E+ ++    I        ++L  +  ES  V    KK + L   K  + T  
Sbjct: 785  LANERKELEIYQN---NIENFKNNAVDRLNVL--ESDLV----KKRNELEQLKKEQQTHY 835

Query: 381  KMKSPWSQLSSETLN-QDTDKKINKNEIAKLEMVIQSLNK-DLVDKEYV-----ISEKDT 433
               +  S L++E    ++  KK    +  K E ++Q+ N   + + E V     ++++  
Sbjct: 836  NELN--SNLTNELQELEEQKKKFAHQKQQKFEELLQAKNNLSIKENELVLYAQKVNDRYN 893

Query: 434  XXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEI 493
                       K  +I   +LE  +H E   L +        N+I   QEQ+K +   +I
Sbjct: 894  ELKAIEKSNTAKSEMI-NAKLEEFKHAEIDYLNY-------QNKIK--QEQIKFDNQVKI 943

Query: 494  KDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIK-VKSNHKLKLKQMQKTIDNFSKVSD 552
             +       E L   EEQI Q   E  A  K + K  K   + K     +  + F+K+S+
Sbjct: 944  LESQYNQRNEILLIREEQIKQKKAEQQAQEKQIQKDFKRLQEEKNNFDDQKRNKFNKISN 1003

Query: 553  SNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETR 612
               EI +  +E+  L+Q+  ++E++K  L   L+    GR+ + ++  ++  +E   +  
Sbjct: 1004 LYLEIKKQRDEV-DLAQR--QIEDQKEEL---LIKAREGRLQKQEIEDRLAVLEKSEKRF 1057

Query: 613  LKAISLLESQKFDLVQELHILQQKYDEVEDKLADIS-QLQSDQVCSEIKSVHLEEQIDAL 671
             +   LL  ++ DL++ + +L+   ++  + L+  S QL       + K   L+ + D L
Sbjct: 1058 RQEDELLAKKRIDLIERIGVLKADINKKHEILSLRSVQLTEKAKKQQEKDADLQRKFDLL 1117

Query: 672  SAS----KKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKM 727
             +      +E     + LK+++++L    K++  +  +I     N     +DL  K  K+
Sbjct: 1118 ESEVERFNEEKKSEFQKLKVERDKLAHREKNVSKNMNEI-----NLALAKLDLIRKNNKV 1172

Query: 728  SAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAV 787
               KI+E LA +N +++   +    +DAK  E    +  +E++L   K ++     +I  
Sbjct: 1173 DKAKINEKLALLNDQKEKIDRENDLLDAKKTEVITRLRKMENDLEFEKQKVLLDRSNIER 1232

Query: 788  MEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDH-DRVVE-------- 838
            +   + +L R+ +     L+ +++++S+    E + ++     + H +R +         
Sbjct: 1233 ISSDQQALARELETKYQTLEREKRSFSQRKENELKEIDDFYQQVQHKERTLNLKIEDLKQ 1292

Query: 839  -KQLLEIEHENKELQKKN-QILLEENQNLQISLSDMQQHYNALVEK-ANRTDLAESESTK 895
             + LLE E  N  + KK+ ++ +E  Q L+ ++ + Q   N       N+ +L   +  K
Sbjct: 1293 LRYLLEKESYNVNVNKKDLKVRIEHYQRLERAIKNEQHKLNNQKNNFFNKVELLNDQLNK 1352

Query: 896  YQTQLRDLESNL----KRITHEHQTLIVQK------KKEIEDLEIEFNTQIESAIRDKKV 945
              +++  L S +    K+   + Q L+ +K      +K +   + E + Q       KK 
Sbjct: 1353 KSSKIALLRSKIYNTYKQQQQQKQILLEEKHKNSQLRKSLLKTQEELHQQKAQFSIAKKQ 1412

Query: 946  LNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTE 1005
              +K +   + +    +++ + K+ I N+   V +L +  L  ++K + KQ+       E
Sbjct: 1413 EEKKLKNQKDLIQNTLSEVIKQKDQITNIKQEV-DLKQTQLNNLEKLIIKQRADLQKELE 1471

Query: 1006 QYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQ 1065
            +      +L    +  +E+   L  + + A+   +S     +  L     K+++  +++ 
Sbjct: 1472 KNSENTYRLQKAERLLEEKKTKLRLEYDKAK-KVLSTAKATDQALKTKQAKVQDQFKKLV 1530

Query: 1066 RVSKQLLDSKQH-NEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDD 1124
             ++K++++++ +  ++  I+ +E +++     +      +N+     ++ + TI P+   
Sbjct: 1531 LINKKIIEARNNLLKQRNIIQKEINNRNMANFQNPYPNFLNLAPNTQVVPAQTIMPV-QT 1589

Query: 1125 ANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTE 1184
               V               + + ++ I ++ +L  Q  +    L+E   K  +L     +
Sbjct: 1590 PQLVGVNYPNQPAFDFNNPLMQMQQLINQQQMLMMQK-EHQWALEEANKKNSRLAKQLKQ 1648

Query: 1185 LTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLA 1244
            L  H     E  ++  +    LN +N   ++++  L S ++    +R   I +L + +L 
Sbjct: 1649 LKHHKQALTESTSEHLNYHNLLNADNSYKINSLQNLLSKVAYNTKRR---INQL-EHNLD 1704

Query: 1245 QREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEE 1304
               AD  +  HEL            QLLD +++     T     +    S   +L+   +
Sbjct: 1705 PETADLNQL-HELNAN--------SQLLDEIRTVLSNTTTNTNAVVPANSYSKELRMLFD 1755

Query: 1305 HLRNLQEKYADVIN-QIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQ 1363
             ++   +K A + N Q E+  ++I     A                   +    +++   
Sbjct: 1756 EIKADFKKQAVLFNTQKEVFTNQINQLAQAVEQGPIEVRKTLESQDQKYQQMFDNFRDAY 1815

Query: 1364 EQSILNINEENAQLKK 1379
            EQ+I  +  EN +++K
Sbjct: 1816 EQNISLLRNENNEVQK 1831



 Score =  105 bits (252), Expect = 1e-20
 Identities = 236/1186 (19%), Positives = 503/1186 (42%), Gaps = 127/1186 (10%)

Query: 453  QLEHQQHMEGPSLIHVGTNTEDVNEI-AKVQEQLKQELND----EIKDVNVKDL-IEKLK 506
            Q E  Q++    +  +  ++  V+ + +  +E+LK+E++D      K  + K L +  L 
Sbjct: 218  QSERLQNLIDERIAKLNNDSYGVSSLDSSTRERLKKEIHDLSEQRKKLQSAKKLHLYNLN 277

Query: 507  SAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHH 566
              +E I +   +++   +++ ++++ H  KLK   + +DN     +  K+         +
Sbjct: 278  LKKESIRRYRSQLEQYLESLKQMRNEHNKKLKGYAQNLDNIKNEVEKAKQ---------N 328

Query: 567  LSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDL 626
             + +  ++ + K N   +                + IE+EN  +    AI          
Sbjct: 329  FNDQQLKILQSKANADQYFA-------------LRKIELENSYKKAKNAILEANKAHAKN 375

Query: 627  VQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLK 686
            VQE   L  K ++ +  L   ++L+ D    +I S+  E      S  K+ LA  + NL+
Sbjct: 376  VQEEQALANKNNKTQRLL---NKLKEDYDRLKIASLSFE------SMRKQSLA-ALNNLQ 425

Query: 687  LDKEQLYGTIKDLENDKEDIMN-KLQNYIQENMDLTDKLEKMSAEKISE------LLAKI 739
             + +Q +  ++  +++++ I+N K+        DL D+  K+  EK ++        A +
Sbjct: 426  DELKQKHNLLERKKHEQDGIVNEKISELEGYRSDLVDQKLKIEREKENQERRYKAAEASL 485

Query: 740  NHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKA 799
            N + Q   +     + K+ E  L   ++ ++  +  +++  LE   + ++ RR  L+++ 
Sbjct: 486  NKKRQEIDELFLEANTKLNEASLKENDLNNQKREILAKLRNLEHLKSEIDQRRRDLDQRE 545

Query: 800  ---DQLGSYLQ---EKQKAYSE--YTIQEDELVNRLAVLMDHDRVVEKQLLEIEH----E 847
                Q    +Q   E ++A  +    I+  +   R   L+ ++R +++Q  + E+    E
Sbjct: 546  LIDQQTIRKIQLDVESERADLQRILLIERKKNDERQQELLQYERDIKRQQTDFENTVNWE 605

Query: 848  NKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLR-DLES- 905
             K+L ++ + L +  + LQ+  S++Q+  + L E+ NR   ++  S   + +L+ DLE  
Sbjct: 606  QKKLSQREKELKDGYEQLQLKQSEVQEKIDELNEEINRAQKSKQNSLVLEQKLKSDLEHL 665

Query: 906  NLKR--ITHEHQTLIVQKKKEIEDLEI---EFNTQIESAIRDKKVLNEKYEKNIEYVTQL 960
            NL +  +  + + L  +  K IEDL++   +   Q E     +K L +K    I +   +
Sbjct: 666  NLSKNYLDKQQEELNQKSDKMIEDLKVFERDLKRQKEDLSIYEKSLQQKEASLINFQNDV 725

Query: 961  EAQLQEYKNNIENLNMNVE--------ELNKMNLELIDKHVQKQQTQSPDYTEQYINEIN 1012
              Q  E  +  + ++  +E        EL K+  E       K++       +++I+E  
Sbjct: 726  TVQKNEAYHKAQAIHQELELKKAAIENELRKLTAERKAVDADKEENTK---LKKFIDE-- 780

Query: 1013 KLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLL 1072
            ++ +L  ++ E  I  N  I N + + +  ++  ES L +   +LE +++E Q    + L
Sbjct: 781  EIRSLANERKELEIYQN-NIENFKNNAVDRLNVLESDLVKKRNELEQLKKEQQTHYNE-L 838

Query: 1073 DSKQHNE--ELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDX 1130
            +S   NE  EL+   ++   Q ++  E  L  + N+   E  ++    + ++D  N +  
Sbjct: 839  NSNLTNELQELEEQKKKFAHQKQQKFEELLQAKNNLSIKENELVLYA-QKVNDRYNELKA 897

Query: 1131 XXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDV 1190
                       +  + EE    E   L  Q+ K+  E  +   ++  LE+   +     +
Sbjct: 898  IEKSNTAKSEMINAKLEEFKHAEIDYLNYQN-KIKQEQIKFDNQVKILESQYNQRNEILL 956

Query: 1191 VNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELW----KQH---- 1242
            + +EQI Q K++ +    +       + E +++       +  +I+ L+    KQ     
Sbjct: 957  IREEQIKQKKAEQQAQEKQIQKDFKRLQEEKNNFDDQKRNKFNKISNLYLEIKKQRDEVD 1016

Query: 1243 LAQREADFQKTE-----HELRVQLSAFESKYEQLLDSVQSSTQEE----TNKIVTMEQVT 1293
            LAQR+ + QK E      E R+Q    E +   L  S +   QE+      +I  +E++ 
Sbjct: 1017 LAQRQIEDQKEELLIKAREGRLQKQEIEDRLAVLEKSEKRFRQEDELLAKKRIDLIERIG 1076

Query: 1294 SLQNKLQDKEEHL-----------RNLQEKYADVINQIEILRSEI----EDEKVAFXXXX 1338
             L+  +  K E L           +  QEK AD+  + ++L SE+    E++K  F    
Sbjct: 1077 VLKADINKKHEILSLRSVQLTEKAKKQQEKDADLQRKFDLLESEVERFNEEKKSEFQKLK 1136

Query: 1339 XXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLK-KSSXXXXXXXXXXXXRVND 1397
                          +  N+    + +  ++  N +  + K                R ND
Sbjct: 1137 VERDKLAHREKNVSKNMNEINLALAKLDLIRKNNKVDKAKINEKLALLNDQKEKIDREND 1196

Query: 1398 -AEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLV--EYEKRIEDLTYE 1454
              +AK  E+  +L   ++++  +  +  + L + N E  +  QQ +  E E + + L  E
Sbjct: 1197 LLDAKKTEVITRLRKMENDL--EFEKQKVLLDRSNIERISSDQQALARELETKYQTLERE 1254

Query: 1455 KESELAILRLKMHENANHYETMQKESEIERVKLIEELNVK-ITESVSLNKQVAELNKALE 1513
            K S       ++ E  + Y+ +Q +     +K+ +   ++ + E  S N  V +  K L+
Sbjct: 1255 KRSFSQRKENELKEIDDFYQQVQHKERTLNLKIEDLKQLRYLLEKESYNVNVNK--KDLK 1312

Query: 1514 EEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVS 1559
              +     ++ A++N++ +   LN++  N  N V   + ++ K  S
Sbjct: 1313 VRIEHYQRLERAIKNEQHK---LNNQKNNFFNKVELLNDQLNKKSS 1355



 Score = 97.9 bits (233), Expect = 2e-18
 Identities = 168/933 (18%), Positives = 381/933 (40%), Gaps = 63/933 (6%)

Query: 669  DALSASKKELALVIENLKLDKEQLY-GTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKM 727
            D    + +E  +  +  KLDK     G       D+ + + K    + +++D   + +  
Sbjct: 37   DGYIKANQENLIANQYKKLDKNSYQNGNNSFYTKDELEKLKKQSFQVNQDIDYYQQAQTE 96

Query: 728  SAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEE---- 783
             + +   LL  I+  E +  Q QF  +    ER   I    +EL +  S +  +E+    
Sbjct: 97   ISSERQRLLQAIDDLEAN--QDQFHPEDFQAERQYLI----NELDRLDSELYHIEQYKND 150

Query: 784  SIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAV-LMDHDRVVEKQLL 842
            SI  + +    L  +  ++ SY     K   +  IQ D+L N+LA    +++ ++ +   
Sbjct: 151  SIDFVNELNQRLSAEQAKIDSYNSSLDKNIRKDYIQIDQLKNKLAEETTEYNDLLNRSTD 210

Query: 843  EIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRD 902
            EI   +++ ++   ++ E    L          Y         + L  S   + + ++ D
Sbjct: 211  EISEIDRQSERLQNLIDERIAKLN------NDSYGV-------SSLDSSTRERLKKEIHD 257

Query: 903  LESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEA 962
            L    K++    +  +     + E +   + +Q+E  +   K +  ++ K ++   Q   
Sbjct: 258  LSEQRKKLQSAKKLHLYNLNLKKESIR-RYRSQLEQYLESLKQMRNEHNKKLKGYAQ--- 313

Query: 963  QLQEYKNNIENL--NMNVEELNKMNLEL-IDKHVQKQQTQSPDYTEQYINEINKLNALLK 1019
             L   KN +E    N N ++L  +  +   D++   ++ +  +  ++  N I + N    
Sbjct: 314  NLDNIKNEVEKAKQNFNDQQLKILQSKANADQYFALRKIELENSYKKAKNAILEANKAHA 373

Query: 1020 QKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDS-KQHN 1078
            +  +E  AL  K N  Q     +  DY+ +L   +   E+M ++       L D  KQ +
Sbjct: 374  KNVQEEQALANKNNKTQRLLNKLKEDYD-RLKIASLSFESMRKQSLAALNNLQDELKQKH 432

Query: 1079 EELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXX 1138
              L+    EQD  + E    K++ E+   +++  ++   ++ +  +  N +         
Sbjct: 433  NLLERKKHEQDGIVNE----KIS-ELEGYRSD--LVDQKLK-IEREKENQERRYKAAEAS 484

Query: 1139 XXXLKVQEEEEFIQERSVLQEQSAK---LNTELQECYTKIIQLETLNTELTGH--DVVNQ 1193
                + + +E F++  + L E S K   LN + +E   K+  LE L +E+     D+  +
Sbjct: 485  LNKKRQEIDELFLEANTKLNEASLKENDLNNQKREILAKLRNLEHLKSEIDQRRRDLDQR 544

Query: 1194 EQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKT 1253
            E I+Q   +  QL+ E++   + +  +        D+R  E+ + +++ + +++ DF+ T
Sbjct: 545  ELIDQQTIRKIQLDVESER--ADLQRILLIERKKNDERQQELLQ-YERDIKRQQTDFENT 601

Query: 1254 EHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKY 1313
             +  + +LS  E + +   + +Q    E   KI   +++    N+ Q  +++   L++K 
Sbjct: 602  VNWEQKKLSQREKELKDGYEQLQLKQSEVQEKI---DELNEEINRAQKSKQNSLVLEQKL 658

Query: 1314 ADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYK------QMQEQSI 1367
               +  + + ++ ++ ++                   DL+ + +         Q +E S+
Sbjct: 659  KSDLEHLNLSKNYLDKQQEELNQKSDKMIEDLKVFERDLKRQKEDLSIYEKSLQQKEASL 718

Query: 1368 LNI-NEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTIT 1426
            +N  N+   Q  ++             +    E ++ +LT + +  D++  + T +    
Sbjct: 719  INFQNDVTVQKNEAYHKAQAIHQELELKKAAIENELRKLTAERKAVDADKEENT-KLKKF 777

Query: 1427 LTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVK 1486
            + +      N R++L  Y+  IE+        L +L   + +  N  E ++KE +    +
Sbjct: 778  IDEEIRSLANERKELEIYQNNIENFKNNAVDRLNVLESDLVKKRNELEQLKKEQQTHYNE 837

Query: 1487 LIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIV-TLNDEITNLQN 1545
            L   L  ++ E     K+ A   +   EE+ +     +  EN+ +     +ND    L+ 
Sbjct: 838  LNSNLTNELQELEEQKKKFAHQKQQKFEELLQAKNNLSIKENELVLYAQKVNDRYNELKA 897

Query: 1546 MVRASSSKIQKHVSFASDTKQGRDEQLDNTMNK 1578
            + +++++K +   +   + K    + L N  NK
Sbjct: 898  IEKSNTAKSEMINAKLEEFKHAEIDYL-NYQNK 929



 Score = 36.3 bits (80), Expect = 7.0
 Identities = 56/256 (21%), Positives = 124/256 (48%), Gaps = 34/256 (13%)

Query: 484  QLKQELNDEIKDVN-VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQK 542
            QL+  L+ E  D+N + +L    +  +E  T L++     N N +   +++  +L+ +  
Sbjct: 1698 QLEHNLDPETADLNQLHELNANSQLLDEIRTVLSNT--TTNTNAVVPANSYSKELRMLFD 1755

Query: 543  TID-NFSKVS---DSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDV 598
             I  +F K +   ++ KE+   T +++ L+Q V     E+G +++        + +ES  
Sbjct: 1756 EIKADFKKQAVLFNTQKEV--FTNQINQLAQAV-----EQGPIEVR-------KTLESQD 1801

Query: 599  YKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSE 658
             K     +N  +   + ISLL ++  ++ ++L  L   YDE+     +  +++   +  E
Sbjct: 1802 QKYQQMFDNFRDAYEQNISLLRNENNEVQKKLTDL---YDEIAAIKTNTEKIKKTTLRPE 1858

Query: 659  IKSVHLE--EQIDALSASKKELA----LVIENLKLDKEQLYGTIKDLENDKEDIMNKLQN 712
            +++   E     ++++  KK+       V +NL++D  Q     +DL + K++ +N+L N
Sbjct: 1859 VRNNANEGLASFNSVNRDKKDYLDQTLPVHQNLRIDLNQN----RDLSHAKKERINQLAN 1914

Query: 713  YIQENMDLTDKLEKMS 728
             I+   +L +K ++ S
Sbjct: 1915 EIKTIKELIEKRKQTS 1930


>UniRef50_Q16IF0 Cluster: Condensin, SMC5-subunit, putative; n=1;
            Aedes aegypti|Rep: Condensin, SMC5-subunit, putative -
            Aedes aegypti (Yellowfever mosquito)
          Length = 1237

 Score =  126 bits (305), Expect = 4e-27
 Identities = 249/1165 (21%), Positives = 497/1165 (42%), Gaps = 137/1165 (11%)

Query: 498  VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEI 557
            + DL +KL  AE  I Q + ++  + +    +K + + ++ ++ + +    K  D  +  
Sbjct: 10   IADLEKKLLKAE--ILQRDQKLHLSEE----LKHSLEDEISKLHERVAEAEKNLDFKESS 63

Query: 558  VRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAIS 617
              ++E+   L +K+A LE+    L + L   D+      ++ K+ ++++N       A  
Sbjct: 64   FNISEQC--LKEKIAYLEDRIEVLGVELTAKDA------ELEKQYLDLKN-------AEG 108

Query: 618  LLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSE--IKSVHLEEQIDALSASK 675
             L+ ++  +V++   +++   E++  L DI Q     +  E  +K+V LEE+  A+   K
Sbjct: 109  QLDEEESLVVEKERQIEKLTGEIQGLLNDIRQRDVKLLEGETGLKAV-LEEKDGAIGKLK 167

Query: 676  KELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKM--SAEKIS 733
            KEL    E L++ +E    + K    D+E  + +L   I  N ++  KLE     A+K+ 
Sbjct: 168  KEL----EELRMKEE----SAKVAVEDRERKLGELNVRIVSNEEIIKKLEDSLKDAKKVE 219

Query: 734  ELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESE--LSKYKSRICRLEESIAVMEDR 791
            + L +    ++  ++ +  + AKIQ+ DL   +  SE  +   +S+   LE+    +E +
Sbjct: 220  QTLEEAIKAKEKSLEEKESLLAKIQD-DLKNSSAGSEQQMVLLRSKESELEQKQHEVEAK 278

Query: 792  RYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKEL 851
            ++ +      + +  ++ ++A  +   +E  L  + A L    +  E  L ++ +   E 
Sbjct: 279  QFQISNLESTITNLTKKLEEAVKD---REARLAEQRASLEFETKSKEDLLNKLANYETEQ 335

Query: 852  QKKNQILLEENQ----NLQISLSDMQQHYNALVEKANRTD--LAESEST--KYQTQLRDL 903
              K++ LLE+N     +LQ  L D++    ++V++   T    A+ +S   K   +   L
Sbjct: 336  LAKDK-LLEDNDVLISSLQTKLKDLEVAKASVVQELEDTTKRFADRDSALRKLNEERMHL 394

Query: 904  ESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQ 963
               L++   E  + I   ++ +++ +      +  A   K+   +        V++LEA 
Sbjct: 395  SEQLEKTRKESASAIALLEERLKNAQKLHEEDVRKA---KEAQKDTLASKDAIVSELEAS 451

Query: 964  LQEYKNNIENLNMNVEELNKMNLEL-IDKHVQKQQTQSPDYTEQY--INE-INKLNALLK 1019
            L + +     L ++ E  +K+N    ++K ++    Q    TE    +N+ +   N  L+
Sbjct: 452  LDKLRQEKTELLLHDELTSKLNENRELNKQIESLTAQLATKTENLDKLNQSLTGTNGKLE 511

Query: 1020 QKDEEIIALNQKINNAQVSYMSM---VSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQ 1076
              + ++I L +     ++ Y  +   +   E K  Q   + +++E+E+  +    LDS  
Sbjct: 512  ATEAKLIELQEAFGKLEIEYADLKRKLEAQEQKSTQLQQQKQDLEKEIDTLRSSTLDS-- 569

Query: 1077 HNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXX 1136
             N EL  +  E   + K+L+E +  F  N  K +       +E   D+AN  +       
Sbjct: 570  -NSELSKVTDELKTKQKQLEELQDAF--NGSKID-------MERRLDEANQTNQGLNEQI 619

Query: 1137 XXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECY-TKIIQLETLNTELTGHDVVNQEQ 1195
                  +V+ E + +  + + +E   +LN EL +   T  I+ E L  E+ G     +E+
Sbjct: 620  D-----RVRNEMQQVSSQKIDREN--ELNVELAKIKETAEIERENLVQEIAGLKASFEEE 672

Query: 1196 INQLK----SKLEQLNTENDNLLSTVAELRSSISS-----------AVDQRGFEIAELWK 1240
             NQL     +K E+  T  + L   V  L  S+S            AV +R  E AE   
Sbjct: 673  RNQLVKGGVAKSEEFETVKEELSGKVKSLEKSLSELERELAKNRECAVKER--EEAEGRL 730

Query: 1241 QHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTME-QVTSLQNKL 1299
            +   ++E   QK   EL+ + S+  +  E L  S++  + + ++++     +++ L+ +L
Sbjct: 731  KEQMEKETTLQKEFDELKKEESSLRAALEDLRQSMEKGSHDASSQLDAKNTKISELEKEL 790

Query: 1300 QDKEEHLRNLQEKYADVINQIEILRSEIED------EKVAFXXXXXXXXXXXXXXXXDLR 1353
            +  +E L   QE+  D   Q+E       D      + +                  ++ 
Sbjct: 791  RSVQEELSRKQEQVDDSTKQLERNAETHSDLLKQLEQNLNQIQELSGDKAKAEGSLKEIS 850

Query: 1354 TENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXR--VNDAEAKVLELTHQLEL 1411
             E  S+K   ++    + EE   LK+ +               V + ++ V EL  +LE 
Sbjct: 851  DELASFKAKYDE----MEEEQVDLKQLNEIERLHKEVKEKESYVFEKDSSVAELRKKLEQ 906

Query: 1412 KDSEIYQ--KTHEYTIT-LTQRNDEFENVRQQLVEYEKRIE----------DLTYEKESE 1458
            K  E  Q  K  EYT   LT+++ + E       E ++ +E          D   E+   
Sbjct: 907  KQEETQQLMKKLEYTEKCLTEKSQQEEKTAATSSELKEALEKSKAAVKEQDDKIKEQGRT 966

Query: 1459 LAILRLKMHENANHYETM---QKESEIE--------RVKLIEELNVKITESVSLNKQVAE 1507
            +  L  K+   +  +E +   +K SE E          KL+E  NVK  E   L+ ++AE
Sbjct: 967  INELETKLSAQSTQFEELLNKKKASETESSHKLHEMNQKLLELENVKQQEISDLSAKLAE 1026

Query: 1508 LNKALE---EEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDT 1564
                 E    E AKT     ++E ++ E+     E+   +  ++ ++ K+QK V      
Sbjct: 1027 TMNRFETQMAESAKTVGSMRSVEKRQYELECEKKEMELRETEMQITTRKLQKEVDLLRSQ 1086

Query: 1565 KQGRDEQLDNTMNKELLDAVPRAEL 1589
               +D ++   + +EL +A   A L
Sbjct: 1087 LLLKDSEV-RKLTQELANAPTSAPL 1110



 Score =  124 bits (299), Expect = 2e-26
 Identities = 213/1012 (21%), Positives = 426/1012 (42%), Gaps = 76/1012 (7%)

Query: 483  EQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQK 542
            E+L  E+   + D+  +D+  KL   E  +  + +E D A   + K     ++K +  + 
Sbjct: 125  EKLTGEIQGLLNDIRQRDV--KLLEGETGLKAVLEEKDGAIGKLKKELEELRMKEESAKV 182

Query: 543  TI-DNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSG-RMIESDVYK 600
             + D   K+ + N  IV   E +  L   + + ++ +  L+  +   +      ES + K
Sbjct: 183  AVEDRERKLGELNVRIVSNEEIIKKLEDSLKDAKKVEQTLEEAIKAKEKSLEEKESLLAK 242

Query: 601  KMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIK 660
               +++N +    + + LL S++ +L Q+ H       EVE K   IS L+S  + +  K
Sbjct: 243  IQDDLKNSSAGSEQQMVLLRSKESELEQKQH-------EVEAKQFQISNLEST-ITNLTK 294

Query: 661  SVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDL 720
               LEE +       +E  L  +   L+ E            KED++NKL NY  E +  
Sbjct: 295  K--LEEAV-----KDREARLAEQRASLEFET---------KSKEDLLNKLANYETEQL-A 337

Query: 721  TDKLEKMSAEKISELLAKINHEEQSK---IQTQFGIDAKIQERDLYIENIESELSKYKSR 777
             DKL + +   IS L  K+   E +K   +Q       +  +RD  +  +  E      +
Sbjct: 338  KDKLLEDNDVLISSLQTKLKDLEVAKASVVQELEDTTKRFADRDSALRKLNEERMHLSEQ 397

Query: 778  ICRLEE----SIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDH 833
            + +  +    +IA++E+R  + ++  ++     +E QK   +    +D +V+ L   +D 
Sbjct: 398  LEKTRKESASAIALLEERLKNAQKLHEEDVRKAKEAQK---DTLASKDAIVSELEASLDK 454

Query: 834  DRVVEKQLL---EIE---HENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTD 887
             R  + +LL   E+    +EN+EL K+ + L  +      +L  + Q       K   T+
Sbjct: 455  LRQEKTELLLHDELTSKLNENRELNKQIESLTAQLATKTENLDKLNQSLTGTNGKLEATE 514

Query: 888  LAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLN 947
                E  +   +L    ++LKR     +    Q +++ +DLE E +T   S +     L+
Sbjct: 515  AKLIELQEAFGKLEIEYADLKRKLEAQEQKSTQLQQQKQDLEKEIDTLRSSTLDSNSELS 574

Query: 948  EKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQY 1007
            +  ++      QLE     +  +  ++   ++E N+ N + +++ + + + +    + Q 
Sbjct: 575  KVTDELKTKQKQLEELQDAFNGSKIDMERRLDEANQTN-QGLNEQIDRVRNEMQQVSSQK 633

Query: 1008 INEINKLN---ALLKQKDE-EIIALNQKINNAQVSY----MSMVSDYESKLAQFTTKLEN 1059
            I+  N+LN   A +K+  E E   L Q+I   + S+      +V    +K  +F T  E 
Sbjct: 634  IDRENELNVELAKIKETAEIERENLVQEIAGLKASFEEERNQLVKGGVAKSEEFETVKEE 693

Query: 1060 MEEEMQRVSKQLLDSKQH---NEELQILVREQ-DDQIKEL--KETKLTFEMNIPKTEGMI 1113
            +  +++ + K L + ++    N E  +  RE+ + ++KE   KET L  E +  K E   
Sbjct: 694  LSGKVKSLEKSLSELERELAKNRECAVKEREEAEGRLKEQMEKETTLQKEFDELKKEESS 753

Query: 1114 ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYT 1173
            + + +E +                     K+ E E+  + RSV QE+ ++   ++ +   
Sbjct: 754  LRAALEDLRQSMEK-GSHDASSQLDAKNTKISELEK--ELRSV-QEELSRKQEQVDDSTK 809

Query: 1174 KIIQLETLNTELTGHDVVNQEQINQL---KSKLE-QLNTENDNLLSTVAELRSSISSAVD 1229
            ++ +    +++L      N  QI +L   K+K E  L   +D L S  A+        VD
Sbjct: 810  QLERNAETHSDLLKQLEQNLNQIQELSGDKAKAEGSLKEISDELASFKAKYDEMEEEQVD 869

Query: 1230 QRGF-EIAELWKQHLAQREADFQKTEH--ELRVQLSAFESKYEQLLDSVQSSTQEETNKI 1286
             +   EI  L K+   +    F+K     ELR +L   + + +QL+  ++ + +  T K 
Sbjct: 870  LKQLNEIERLHKEVKEKESYVFEKDSSVAELRKKLEQKQEETQQLMKKLEYTEKCLTEKS 929

Query: 1287 VTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQ----IEILRSEIEDEKVAFXXXXXXXX 1342
               E+  +  ++L++  E  +   ++  D I +    I  L +++  +   F        
Sbjct: 930  QQEEKTAATSSELKEALEKSKAAVKEQDDKIKEQGRTINELETKLSAQSTQFEELLNKKK 989

Query: 1343 XXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKV 1402
                     L   NQ   +++      I++ +A+L ++              V    + V
Sbjct: 990  ASETESSHKLHEMNQKLLELENVKQQEISDLSAKLAETMNRFETQMAESAKTVGSMRS-V 1048

Query: 1403 LELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYE 1454
             +  ++LE +  E+  +  E  IT  +   E + +R QL+  +  +  LT E
Sbjct: 1049 EKRQYELECEKKEMELRETEMQITTRKLQKEVDLLRSQLLLKDSEVRKLTQE 1100



 Score =  108 bits (259), Expect = 1e-21
 Identities = 203/1003 (20%), Positives = 436/1003 (43%), Gaps = 112/1003 (11%)

Query: 90   ISESLANTLKQKEILMEKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSN 149
            + +SL +  K ++ L E IK  KE S     +++                Q+  +    +
Sbjct: 208  LEDSLKDAKKVEQTLEEAIKA-KEKSLEEKESLLAKIQDDLKNSSAGSEQQMVLLRSKES 266

Query: 150  TIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXX 209
             +++K + +   Q ++  +E+TI +L +K+ E  +  EA+                    
Sbjct: 267  ELEQKQHEVEAKQFQISNLESTITNLTKKLEEAVKDREAR------------------LA 308

Query: 210  XXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISL 269
                + +  TK +E+ +   A ++ E+    K +E  DV ISSL+   K LE A+     
Sbjct: 309  EQRASLEFETKSKEDLLNKLANYETEQLAKDKLLEDNDVLISSLQTKLKDLEVAK----- 363

Query: 270  EHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIE 329
              + + QELE               L ++ +  S E+  +  ++ +  IA + E  K  +
Sbjct: 364  --ASVVQELEDTTKRFADRDSALRKLNEERMHLS-EQLEKTRKESASAIALLEERLKNAQ 420

Query: 330  LLEHLNC-QIRQTNKE-LENKLATMGTESKAVSSPSKKGSPLI-------SRKSGRNTAS 380
             L   +  + ++  K+ L +K A +     ++    ++ + L+            R    
Sbjct: 421  KLHEEDVRKAKEAQKDTLASKDAIVSELEASLDKLRQEKTELLLHDELTSKLNENRELNK 480

Query: 381  KMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXX 440
            +++S  +QL+++T N D   K+N++ +      +++    L++ +    + +        
Sbjct: 481  QIESLTAQLATKTENLD---KLNQS-LTGTNGKLEATEAKLIELQEAFGKLEIEYADLKR 536

Query: 441  XXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVN-EIAKVQEQL--KQELNDEIKDV- 496
                ++    QLQ + +Q +E   +  + ++T D N E++KV ++L  KQ+  +E++D  
Sbjct: 537  KLEAQEQKSTQLQ-QQKQDLE-KEIDTLRSSTLDSNSELSKVTDELKTKQKQLEELQDAF 594

Query: 497  --NVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSN 554
              +  D+  +L  A +    LN++ID     M +V S    +  ++   +    + ++  
Sbjct: 595  NGSKIDMERRLDEANQTNQGLNEQIDRVRNEMQQVSSQKIDRENELNVELAKIKETAEIE 654

Query: 555  KEIVRLTEELHHLSQKVAELEEEKGNL---------QLHLVDYDSGRMIESDVYKKMIEM 605
            +E   L +E+  L    A  EEE+  L         +   V  +    ++S + K + E+
Sbjct: 655  RE--NLVQEIAGLK---ASFEEERNQLVKGGVAKSEEFETVKEELSGKVKS-LEKSLSEL 708

Query: 606  E-NLAETRLKAISLLESQKFDLVQELH---ILQQKYDEVEDKLADISQLQSDQVCSEIKS 661
            E  LA+ R  A+   E  +  L +++     LQ+++DE++ + + +     D   S  K 
Sbjct: 709  ERELAKNRECAVKEREEAEGRLKEQMEKETTLQKEFDELKKEESSLRAALEDLRQSMEKG 768

Query: 662  VH-LEEQIDA----LSASKKELALVIENLKLDKEQLYGTIKDLENDKE---DIMNKLQNY 713
             H    Q+DA    +S  +KEL  V E L   +EQ+  + K LE + E   D++ +L+  
Sbjct: 769  SHDASSQLDAKNTKISELEKELRSVQEELSRKQEQVDDSTKQLERNAETHSDLLKQLEQN 828

Query: 714  IQENMDLT-DKLE-KMSAEKISELLA--KINHEEQSKIQTQFGIDAKIQERDLYIENIES 769
            + +  +L+ DK + + S ++IS+ LA  K  ++E  + Q    +D K       IE +  
Sbjct: 829  LNQIQELSGDKAKAEGSLKEISDELASFKAKYDEMEEEQ----VDLKQLNE---IERLHK 881

Query: 770  ELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAV 829
            E+ + +S +   + S+A +  +    + +  QL   L+  +K  +E + QE++     A 
Sbjct: 882  EVKEKESYVFEKDSSVAELRKKLEQKQEETQQLMKKLEYTEKCLTEKSQQEEKTA---AT 938

Query: 830  LMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTD-- 887
              +    +EK    ++ ++ +++++ + + E    L    +  ++  N   +KA+ T+  
Sbjct: 939  SSELKEALEKSKAAVKEQDDKIKEQGRTINELETKLSAQSTQFEELLNK--KKASETESS 996

Query: 888  ---------LAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIES 938
                     L E E+ K Q ++ DL + L    +  +T + +  K +  +      Q E 
Sbjct: 997  HKLHEMNQKLLELENVK-QQEISDLSAKLAETMNRFETQMAESAKTVGSMRSVEKRQYEL 1055

Query: 939  AIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIEN-LNMNVEELNKMNLELIDKHVQKQQ 997
                K++  E  E  ++  T+   +LQ+  + + + L +   E+ K+  EL +       
Sbjct: 1056 ECEKKEM--ELRETEMQITTR---KLQKEVDLLRSQLLLKDSEVRKLTQELANAPTSAPL 1110

Query: 998  TQSPDY---TEQYINEINKLNALLKQKDEEIIALNQKINNAQV 1037
              S +    TE  I+ +N + A +++K++++    Q +    +
Sbjct: 1111 ISSAEANGDTEAQISFLNSIIADMQRKNDKLTLRIQALEQTSI 1153



 Score = 70.1 bits (164), Expect = 5e-10
 Identities = 130/677 (19%), Positives = 284/677 (41%), Gaps = 78/677 (11%)

Query: 922  KKEIEDLEIEFNTQIESAIRDKKV-LNEKYEKNIE-YVTQLEAQLQEYKNNIE--NLNMN 977
            K+ I DLE +   + E   RD+K+ L+E+ + ++E  +++L  ++ E + N++    + N
Sbjct: 7    KERIADLEKKL-LKAEILQRDQKLHLSEELKHSLEDEISKLHERVAEAEKNLDFKESSFN 65

Query: 978  V-EELNKMNLELIDKHVQ----KQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKI 1032
            + E+  K  +  ++  ++    +   +  +  +QY+ ++      L +++  ++   ++I
Sbjct: 66   ISEQCLKEKIAYLEDRIEVLGVELTAKDAELEKQYL-DLKNAEGQLDEEESLVVEKERQI 124

Query: 1033 NNAQVSYMSMVSDYES---KLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQD 1089
                     +++D      KL +  T L+ + EE      +L   K+  EEL++  +E+ 
Sbjct: 125  EKLTGEIQGLLNDIRQRDVKLLEGETGLKAVLEEKDGAIGKL---KKELEELRM--KEES 179

Query: 1090 DQIK-ELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEE 1148
             ++  E +E KL  E+N+       I   +E    DA  V+              ++ +E
Sbjct: 180  AKVAVEDRERKLG-ELNVRIVSNEEIIKKLEDSLKDAKKVEQTLEEA--------IKAKE 230

Query: 1149 EFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNT 1208
            + ++E+  L    AK+  +L+       Q   L           + ++ Q + ++E    
Sbjct: 231  KSLEEKESLL---AKIQDDLKNSSAGSEQQMVLLRS-------KESELEQKQHEVEAKQF 280

Query: 1209 ENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQ-KTEHELRVQLSAFESK 1267
            +  NL ST+  L   +  AV  R   +AE       +   +F+ K++ +L  +L+ +E+ 
Sbjct: 281  QISNLESTITNLTKKLEEAVKDREARLAE------QRASLEFETKSKEDLLNKLANYET- 333

Query: 1268 YEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRS-- 1325
             EQL          E N ++    ++SLQ KL+D E    ++ ++  D   +     S  
Sbjct: 334  -EQLA----KDKLLEDNDVL----ISSLQTKLKDLEVAKASVVQELEDTTKRFADRDSAL 384

Query: 1326 -EIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXX 1384
             ++ +E++                   L    ++ +++ E+ +    E       S    
Sbjct: 385  RKLNEERMHLSEQLEKTRKESASAIALLEERLKNAQKLHEEDVRKAKEAQKDTLASKDAI 444

Query: 1385 XXXXXXXXXRVNDAEAKVL---ELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQL 1441
                     ++   + ++L   ELT +L  ++ E+ ++    T  L  + +  + + Q L
Sbjct: 445  VSELEASLDKLRQEKTELLLHDELTSKLN-ENRELNKQIESLTAQLATKTENLDKLNQSL 503

Query: 1442 VEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSL 1501
                 ++E       +E  ++ L+        E   K  EIE   L  +L  +  +S  L
Sbjct: 504  TGTNGKLE------ATEAKLIELQ--------EAFGK-LEIEYADLKRKLEAQEQKSTQL 548

Query: 1502 NKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFA 1561
             +Q  +L K ++   + T +  + L     E+ T   ++  LQ+    S   +++ +  A
Sbjct: 549  QQQKQDLEKEIDTLRSSTLDSNSELSKVTDELKTKQKQLEELQDAFNGSKIDMERRLDEA 608

Query: 1562 SDTKQGRDEQLDNTMNK 1578
            + T QG +EQ+D   N+
Sbjct: 609  NQTNQGLNEQIDRVRNE 625


>UniRef50_A0E6F4 Cluster: Chromosome undetermined scaffold_8, whole
            genome shotgun sequence; n=2; Paramecium tetraurelia|Rep:
            Chromosome undetermined scaffold_8, whole genome shotgun
            sequence - Paramecium tetraurelia
          Length = 1391

 Score =  126 bits (305), Expect = 4e-27
 Identities = 221/1146 (19%), Positives = 489/1146 (42%), Gaps = 112/1146 (9%)

Query: 474  DVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNH 533
            D+ +    Q + KQ+L  E+K        + +++ +   +Q   +I     ++  + S++
Sbjct: 130  DLQQQINEQNKYKQKLEAELKFYKDNRFTQTIETQDMNFSQNQRKIKEMEDDIQILISDY 189

Query: 534  KLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRM 593
                ++++K ++   +   S  +I ++  ++  LS ++   ++   NL++  ++ ++   
Sbjct: 190  SRNQEKLEKALNE--QKQQSKYDIDQMKSQIQSLSSQIQGWQQRYQNLEIMKIELEN--- 244

Query: 594  IESDVYKKMIEMENLAETRLKAISLLESQ-KFDLVQELHI-LQQKYDEVEDKLADISQLQ 651
                   K+I +E   +  +   S  ESQ   D V +L   + Q++ ++ D  A+I Q Q
Sbjct: 245  -------KLIILEKENQQLIGKSSYRESQANLDTVSQLKDQIYQQFKQINDLKAEIQQKQ 297

Query: 652  SDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKE--QLYGTIKDLENDKEDIMNK 709
              +     +  +L+++++  S S+   +  +EN +   E  +L   I+ L+ + E+   +
Sbjct: 298  QSEYQLIKEQQNLKQKLEQ-SQSQTYNSQQVENTQYVNEIFKLKQYIEQLQYENENYRTQ 356

Query: 710  LQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQS--KIQTQFGIDAKIQERDLYIENI 767
              N  Q   +++ K E    ++I+  L +I   + +   +QTQ+      QE    IE +
Sbjct: 357  KSNLYQNQTNISSK-EVQQNQQINAYLEEIERLKGNIFSLQTQYEKQLNDQENRFQIE-L 414

Query: 768  ESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEK---QKAYSEYTIQEDELV 824
            +S   K+ S+   L     + E+ R++ + +     + +Q K    K Y + T+ ED L+
Sbjct: 415  KSVSDKFVSQQKELNCKTQIFEESRFTFQNQQQIQENDIQTKIWQDKFYEQQTLNED-LM 473

Query: 825  NRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEK-- 882
             +   L +          + E++ K +Q   + L+EE QN+  SL   + HY   + +  
Sbjct: 474  YKHQELRNQLTQYLNYKTQNEYDQKTIQNL-EALVEEQQNIMHSLYQKELHYKDTINQYM 532

Query: 883  --------------ANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDL 928
                           N+    + +  + Q +LRD ES L       +   ++++ E+E L
Sbjct: 533  LIIEEHQQRNNGVFENQIQQLQLQLDQLQIKLRDQESQLN--IKSSKCFDLERQIEVEKL 590

Query: 929  EI-EFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVE-ELNKMNL 986
               E  +     ++ +K+  ++ E  ++ + +  A   + +N +    + VE + ++  +
Sbjct: 591  RFSERESLFSQQLKQEKIRIQQLELQVDNLQKDMALQNQKRNEVIKEYIYVENQQDQERI 650

Query: 987  ELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDE---------EIIALNQKINNAQV 1037
             L+++ +Q  Q +     EQYI   N+ NA + Q ++         +I  L +++   + 
Sbjct: 651  ILLEQSLQNLQQEYLLMKEQYICVQNQYNAQIIQIEQLQGLQEDKSKIRQLEEQLRMLKD 710

Query: 1038 SYMSMVSDYESKLAQFTTK------------LENMEEEMQRVSKQ--LLDSKQHNEELQI 1083
             Y  + +  +  L +   +            ++ + +E+Q++  +  +L++++ N  ++I
Sbjct: 711  QYFELNTLKQQVLKEVVKEVIEVPSQSDQILIKELRQELQQLQSEYRILNAQKQNY-VEI 769

Query: 1084 LVREQDDQIKELKETKLT----FEMNIPKTEGMIISSTIEPMSDDANNV---DXXXXXXX 1136
                  ++IKEL++  +T    +E    K +  I          D   +   +       
Sbjct: 770  QSEVDKNRIKELEKQLITLRRDYEEVCNKKQSQITEFVEVSSKQDLQRIQQLEKIVQQLQ 829

Query: 1137 XXXXXLKVQEEEEFI------QERSVLQEQSAKLNTELQECYTKIIQLETLNTEL---TG 1187
                 L++Q  E+        Q+R  +QE S +L T  QE      QL   N  L     
Sbjct: 830  EENFKLQIQSNEQIKKSVIVNQDREQVQELSVQLATLKQENKALHQQLNQQNESLRKSQN 889

Query: 1188 HDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQRE 1247
             D +  +Q+ Q    LEQ N E  N  S +  ++ ++  + D+  F+I +L  Q L  + 
Sbjct: 890  SDFLKIQQLEQKIRILEQSNFEVQNQQSQIKIVKETVEVSKDEDVFKIQQLELQ-LQVKT 948

Query: 1248 ADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLR 1307
             D Q  E +L +Q    +   E+L+ + +    E T     + ++ S  ++LQ K +   
Sbjct: 949  DDIQYLEKQLNLQ----KKNVEELISANEKMKYENTKMRQQLYELQSSIDELQLKIKENN 1004

Query: 1308 NLQE---KYADVINQI---EILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQ 1361
              QE   +Y  +I+Q    E L+++ ++                     +     Q Y+ 
Sbjct: 1005 QFQEETKQYKQMISQYEQREKLKNDSQELVTELKRKLNESENQIKRQWGEFELSKQDYEF 1064

Query: 1362 MQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTH 1421
              +      N++  QL++               ++    K      Q+++++ E+ ++ +
Sbjct: 1065 KLKSQETKYNQQIQQLQQ-EFQMKQQSKEDEYYISKNSFK------QMQMQNDELQREIN 1117

Query: 1422 EYTITLTQRNDEFENVRQQLVEYEKRIEDLTYE-KESELAILRLKMHENANHYETMQKES 1480
              +  + Q++DE + +  ++  Y  +++      KE+++ I    + +     + MQK +
Sbjct: 1118 RLSDLIRQKSDEIKKLNDKISAYAVKLDQQQSNLKENQIQIQDYSLQQE-KMSQLMQKNN 1176

Query: 1481 EIER-VKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDE 1539
            ++E  +K  EE   K  E++ L+KQ       ++E + K +     L N    IVTL ++
Sbjct: 1177 KLENALKQFEE--EKKIENLELHKQFNIKVMEIQEIIQKKDNEIQQLSNY---IVTLKEQ 1231

Query: 1540 ITNLQN 1545
            I N +N
Sbjct: 1232 IKNQEN 1237



 Score =  114 bits (275), Expect = 2e-23
 Identities = 162/781 (20%), Positives = 348/781 (44%), Gaps = 81/781 (10%)

Query: 445  KDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEK 504
            KDT I Q  L  ++H +  +    G     + ++    +QL+ +L D+   +N+K    K
Sbjct: 525  KDT-INQYMLIIEEHQQRNN----GVFENQIQQLQLQLDQLQIKLRDQESQLNIKS--SK 577

Query: 505  LKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSK----VSDSNKEIVR- 559
                E QI               +     K++++Q++  +DN  K     +    E+++ 
Sbjct: 578  CFDLERQIEVEKLRFSERESLFSQQLKQEKIRIQQLELQVDNLQKDMALQNQKRNEVIKE 637

Query: 560  -LTEELHHLSQKVAELEEEKGNLQL-HLVDYDSGRMIESDVYKKMIEMENLA---ETRLK 614
             +  E     +++  LE+   NLQ  +L+  +    +++    ++I++E L    E + K
Sbjct: 638  YIYVENQQDQERIILLEQSLQNLQQEYLLMKEQYICVQNQYNAQIIQIEQLQGLQEDKSK 697

Query: 615  AISLLESQKF--DLVQELHIL-QQKYDEVEDKLADISQLQSDQVC-SEIKSV--HLEEQI 668
               L E  +   D   EL+ L QQ   EV  ++ ++   QSDQ+   E++     L+ + 
Sbjct: 698  IRQLEEQLRMLKDQYFELNTLKQQVLKEVVKEVIEVPS-QSDQILIKELRQELQQLQSEY 756

Query: 669  DALSASKKELALVIENLKLDK-EQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKM 727
              L+A K+    +   +  ++ ++L   +  L  D E++ NK Q+ I E ++++ K +  
Sbjct: 757  RILNAQKQNYVEIQSEVDKNRIKELEKQLITLRRDYEEVCNKKQSQITEFVEVSSKQDLQ 816

Query: 728  SAEKISELLAKINHEEQSKIQTQFGIDAK-----------IQERDLYIENIESE------ 770
              +++ +++ ++  EE  K+Q Q     K           +QE  + +  ++ E      
Sbjct: 817  RIQQLEKIVQQLQ-EENFKLQIQSNEQIKKSVIVNQDREQVQELSVQLATLKQENKALHQ 875

Query: 771  --------LSKYKS----RICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTI 818
                    L K ++    +I +LE+ I ++E   + ++ +  Q+    +  + +  E   
Sbjct: 876  QLNQQNESLRKSQNSDFLKIQQLEQKIRILEQSNFEVQNQQSQIKIVKETVEVSKDEDVF 935

Query: 819  QEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNA 878
            +  +L  +L V  D  + +EKQL   +   +EL   N+ +  EN  ++  L ++Q   + 
Sbjct: 936  KIQQLELQLQVKTDDIQYLEKQLNLQKKNVEELISANEKMKYENTKMRQQLYELQSSIDE 995

Query: 879  LVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIES 938
            L  K    +  + E+ +Y+  +   E   +++ ++ Q L+ + K+++ + E     QI+ 
Sbjct: 996  LQLKIKENNQFQEETKQYKQMISQYEQR-EKLKNDSQELVTELKRKLNESE----NQIKR 1050

Query: 939  AIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMN--VEELNKMNLELIDKHVQKQ 996
               + ++  + YE       +L++Q  +Y   I+ L     +++ +K +   I K+  KQ
Sbjct: 1051 QWGEFELSKQDYE------FKLKSQETKYNQQIQQLQQEFQMKQQSKEDEYYISKNSFKQ 1104

Query: 997  QTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQV---SYMSMVSDYESKLAQF 1053
                 D  ++   EIN+L+ L++QK +EI  LN KI+   V      S + + + ++  +
Sbjct: 1105 MQMQNDELQR---EINRLSDLIRQKSDEIKKLNDKISAYAVKLDQQQSNLKENQIQIQDY 1161

Query: 1054 TTKLENMEEEMQRVSKQLLDSKQHNEELQI----LVREQDDQIKELKETKLTFEMNIPKT 1109
            + + E M + MQ+ +K     KQ  EE +I    L ++ + ++ E++E     +  I + 
Sbjct: 1162 SLQQEKMSQLMQKNNKLENALKQFEEEKKIENLELHKQFNIKVMEIQEIIQKKDNEIQQL 1221

Query: 1110 EGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEE--EEFIQERSVLQEQSAKLNTE 1167
               I++   E + +  NN              L+ Q    ++ +  ++ L+E+    N E
Sbjct: 1222 SNYIVTLK-EQIKNQENNKSQKQNDNQQFLIDLQNQLSIVKQDLMRQTTLKEEYQNKNNE 1280

Query: 1168 L 1168
            L
Sbjct: 1281 L 1281



 Score = 99.5 bits (237), Expect = 7e-19
 Identities = 224/1084 (20%), Positives = 467/1084 (43%), Gaps = 143/1084 (13%)

Query: 504  KLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEE 563
            K +  ++ I+   D  +  NK  + +KS      +  QK +    ++S + +E+ R+  +
Sbjct: 51   KREEQKQGISYYRDLCEQLNKENLLLKSFQIENNELKQKLLLINVELSAAQQELSRIRNQ 110

Query: 564  LHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQK 623
            L   SQ+  +   +K  +Q   VD    ++ E + YK+ +E E       +    +E+Q 
Sbjct: 111  LG--SQQPTDRYIQK--IQQDNVDLQQ-QINEQNKYKQKLEAELKFYKDNRFTQTIETQD 165

Query: 624  FDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIE 683
             +  Q     Q+K  E+ED   DI  L SD   ++ K   LE+   AL+  K++      
Sbjct: 166  MNFSQN----QRKIKEMED---DIQILISDYSRNQEK---LEK---ALNEQKQQS----- 207

Query: 684  NLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEE 743
              K D +Q+   I+ L +  +    + QN     ++L +KL  +  E   +L+ K ++ E
Sbjct: 208  --KYDIDQMKSQIQSLSSQIQGWQQRYQNLEIMKIELENKLIILEKEN-QQLIGKSSYRE 264

Query: 744  QSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLG 803
                 +Q  +D   Q +D   +  + +++  K+ I + ++S   +   + +L++K +Q  
Sbjct: 265  -----SQANLDTVSQLKDQIYQQFK-QINDLKAEIQQKQQSEYQLIKEQQNLKQKLEQ-- 316

Query: 804  SYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQ 863
                 + + Y+   ++  + VN +  L  +   +E+  L+ E+EN   QK N  L +   
Sbjct: 317  ----SQSQTYNSQQVENTQYVNEIFKLKQY---IEQ--LQYENENYRTQKSN--LYQNQT 365

Query: 864  NLQISLSDMQQHYNALVEKANRTD-LAESESTKYQTQLRDLESNLKRITHEHQTLIVQKK 922
            N+        Q  NA +E+  R      S  T+Y+ QL D E+  +          V ++
Sbjct: 366  NISSKEVQQNQQINAYLEEIERLKGNIFSLQTQYEKQLNDQENRFQIELKSVSDKFVSQQ 425

Query: 923  KEI-------EDLEIEFNTQIESAIRD--KKVLNEKYEKNIEYVTQLEAQLQEYKNNI-E 972
            KE+       E+    F  Q +    D   K+  +K+ +       L  + QE +N + +
Sbjct: 426  KELNCKTQIFEESRFTFQNQQQIQENDIQTKIWQDKFYEQQTLNEDLMYKHQELRNQLTQ 485

Query: 973  NLNMNVE-ELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQK 1031
             LN   + E ++  ++ ++  V++QQ       ++ ++  + +N  +      II  +Q+
Sbjct: 486  YLNYKTQNEYDQKTIQNLEALVEEQQNIMHSLYQKELHYKDTINQYML-----IIEEHQQ 540

Query: 1032 INNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQ 1091
             NN    + + +   + +L Q   KL + E ++   S +  D ++  E  ++   E++  
Sbjct: 541  RNNGV--FENQIQQLQLQLDQLQIKLRDQESQLNIKSSKCFDLERQIEVEKLRFSERESL 598

Query: 1092 I-KELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEF 1150
              ++LK+ K+  +    + + +     ++  +   N V             + V+ +++ 
Sbjct: 599  FSQQLKQEKIRIQQLELQVDNLQKDMALQ--NQKRNEV---------IKEYIYVENQQD- 646

Query: 1151 IQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQL---KSKLEQLN 1207
             QER +L EQS +    LQ+ Y  + +            ++  EQ+  L   KSK+ QL 
Sbjct: 647  -QERIILLEQSLQ---NLQQEYLLMKEQYICVQNQYNAQIIQIEQLQGLQEDKSKIRQLE 702

Query: 1208 TENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESK 1267
             +   L     EL +     + +   E+ E+  Q      +D Q    ELR +L   +S+
Sbjct: 703  EQLRMLKDQYFELNTLKQQVLKEVVKEVIEVPSQ------SD-QILIKELRQELQQLQSE 755

Query: 1268 YEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEI 1327
            Y  L         ++ N +    +V   +N++++ E+ L  L+  Y +V N+ +   +E 
Sbjct: 756  YRIL-------NAQKQNYVEIQSEVD--KNRIKELEKQLITLRRDYEEVCNKKQSQITEF 806

Query: 1328 EDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXX 1387
             +                      ++   +  +Q+QE++     + N Q+KKS       
Sbjct: 807  VE-------------VSSKQDLQRIQQLEKIVQQLQEENFKLQIQSNEQIKKSVI----- 848

Query: 1388 XXXXXXRVNDAEAKVLELTHQLELKDSE---IYQKTHEYTITLTQ-RNDEFENVRQQLVE 1443
                   VN    +V EL+ QL     E   ++Q+ ++   +L + +N +F  + QQL +
Sbjct: 849  -------VNQDREQVQELSVQLATLKQENKALHQQLNQQNESLRKSQNSDFLKI-QQLEQ 900

Query: 1444 YEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIE-ELNVKITESVSLN 1502
              + +E   +E +++ + +++ + E       + K+ ++ +++ +E +L VK  +   L 
Sbjct: 901  KIRILEQSNFEVQNQQSQIKI-VKETVE----VSKDEDVFKIQQLELQLQVKTDDIQYLE 955

Query: 1503 KQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFAS 1562
            KQ+    K +EE ++       A E  + E   +  ++  LQ+ +     KI+++  F  
Sbjct: 956  KQLNLQKKNVEELIS-------ANEKMKYENTKMRQQLYELQSSIDELQLKIKENNQFQE 1008

Query: 1563 DTKQ 1566
            +TKQ
Sbjct: 1009 ETKQ 1012



 Score = 96.3 bits (229), Expect = 6e-18
 Identities = 114/636 (17%), Positives = 296/636 (46%), Gaps = 37/636 (5%)

Query: 477  EIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDE---IDAANKNMIKVKSN- 532
            E+  +++Q+ +E+  E+ +V  +     +K   +++ QL  E   ++A  +N ++++S  
Sbjct: 714  ELNTLKQQVLKEVVKEVIEVPSQSDQILIKELRQELQQLQSEYRILNAQKQNYVEIQSEV 773

Query: 533  HKLKLKQMQKTIDNFSKVSDS--NKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDS 590
             K ++K+++K +    +  +   NK+  ++TE +   S++  +  ++   +   L + + 
Sbjct: 774  DKNRIKELEKQLITLRRDYEEVCNKKQSQITEFVEVSSKQDLQRIQQLEKIVQQLQEENF 833

Query: 591  GRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQL 650
               I+S+   K   + N    +++ +S+   Q   L QE   L Q+ ++  + L      
Sbjct: 834  KLQIQSNEQIKKSVIVNQDREQVQELSV---QLATLKQENKALHQQLNQQNESLRKSQNS 890

Query: 651  QSDQVCSEIKSVHLEEQID-ALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNK 709
               ++    + + + EQ +  +   + ++ +V E +++ K++    I+ LE   +   + 
Sbjct: 891  DFLKIQQLEQKIRILEQSNFEVQNQQSQIKIVKETVEVSKDEDVFKIQQLELQLQVKTDD 950

Query: 710  LQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYI-EN-- 766
            +Q Y+++ ++L    +K + E++     K+ +E     Q  + + + I E  L I EN  
Sbjct: 951  IQ-YLEKQLNL----QKKNVEELISANEKMKYENTKMRQQLYELQSSIDELQLKIKENNQ 1005

Query: 767  IESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNR 826
             + E  +YK  I + E+   +  D +  +     +L     + ++ + E+ + + +   +
Sbjct: 1006 FQEETKQYKQMISQYEQREKLKNDSQELVTELKRKLNESENQIKRQWGEFELSKQDYEFK 1065

Query: 827  LAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEEN--QNLQISLSDMQQHYNALVE--- 881
            L    +     + Q L+ E + K+  K+++  + +N  + +Q+   ++Q+  N L +   
Sbjct: 1066 LKS-QETKYNQQIQQLQQEFQMKQQSKEDEYYISKNSFKQMQMQNDELQREINRLSDLIR 1124

Query: 882  -KANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAI 940
             K++       + + Y  +L   +SNLK    + Q   +Q++K +  L ++ N ++E+A+
Sbjct: 1125 QKSDEIKKLNDKISAYAVKLDQQQSNLKENQIQIQDYSLQQEK-MSQL-MQKNNKLENAL 1182

Query: 941  RDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELID--KHVQKQQT 998
              K+   EK  +N+E   Q   ++ E +  I+  +  +++L+   + L +  K+ +  ++
Sbjct: 1183 --KQFEEEKKIENLELHKQFNIKVMEIQEIIQKKDNEIQQLSNYIVTLKEQIKNQENNKS 1240

Query: 999  QSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYES------KLAQ 1052
            Q  +  +Q++ ++    +++KQ       L ++  N     +  +++YE       K   
Sbjct: 1241 QKQNDNQQFLIDLQNQLSIVKQDLMRQTTLKEEYQNKNNELLLKIAEYEKGNRISVKSDY 1300

Query: 1053 FTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQ 1088
            F T++       + +    +D  Q++ + QI  +++
Sbjct: 1301 FVTEMYQGTGSFRNLGNASVDFNQNDSQFQIASQQR 1336



 Score = 69.3 bits (162), Expect = 8e-10
 Identities = 114/559 (20%), Positives = 248/559 (44%), Gaps = 48/559 (8%)

Query: 216  QQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLA 275
            Q  T  QEN  A+  +   + + L K   S  ++I  LE+  ++LE + FE+  + S++ 
Sbjct: 862  QLATLKQENK-ALHQQLNQQNESLRKSQNSDFLKIQQLEQKIRILEQSNFEVQNQQSQIK 920

Query: 276  QELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLN 335
               E               L  Q ++   ++   +E++ +L+  N+ EL    E +++ N
Sbjct: 921  IVKETVEVSKDEDVFKIQQLELQ-LQVKTDDIQYLEKQLNLQKKNVEELISANEKMKYEN 979

Query: 336  CQIRQTNKELENKLATMG---TESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSE 392
             ++RQ   EL++ +  +     E+      +K+   +IS+   R    K+K+      S+
Sbjct: 980  TKMRQQLYELQSSIDELQLKIKENNQFQEETKQYKQMISQYEQR---EKLKN-----DSQ 1031

Query: 393  TLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQL 452
             L  +  +K+N++E  +++           D E+ +  ++T            +  I QL
Sbjct: 1032 ELVTELKRKLNESE-NQIKRQWGEFELSKQDYEFKLKSQETKY----------NQQIQQL 1080

Query: 453  QLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQI 512
            Q E Q   +         + ED   I+K   +  Q  NDE++   +  L + ++   ++I
Sbjct: 1081 QQEFQMKQQ---------SKEDEYYISKNSFKQMQMQNDELQR-EINRLSDLIRQKSDEI 1130

Query: 513  TQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVA 572
             +LND+I A    + + +SN    LK+ Q  I ++S   +   ++++   +L + + K  
Sbjct: 1131 KKLNDKISAYAVKLDQQQSN----LKENQIQIQDYSLQQEKMSQLMQKNNKLEN-ALKQF 1185

Query: 573  ELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHI 632
            E E++  NL+LH         I+  + KK  E++ L+   +     +++Q+ +  Q+ + 
Sbjct: 1186 EEEKKIENLELHKQFNIKVMEIQEIIQKKDNEIQQLSNYIVTLKEQIKNQENNKSQKQND 1245

Query: 633  LQQKYDEVEDKLADISQ--LQSDQVCSEIKSVHLEEQIDALSASK-KELALVIENLKLDK 689
             QQ   +++++L+ + Q  ++   +  E ++ + E  +      K   +++  +    + 
Sbjct: 1246 NQQFLIDLQNQLSIVKQDLMRQTTLKEEYQNKNNELLLKIAEYEKGNRISVKSDYFVTEM 1305

Query: 690  EQLYGTIKDLENDKEDI-MNKLQNYIQENMDLTD--KLEKMSAEKISELLAKINHEEQSK 746
             Q  G+ ++L N   D   N  Q  I     + D  +++   A   + L + +N  +Q +
Sbjct: 1306 YQGTGSFRNLGNASVDFNQNDSQFQIASQQRIRDSTRMQNPKANNFNPLNSFVNIFKQFR 1365

Query: 747  IQTQFGIDAKIQERDLYIE 765
               Q   ++ +++R  YIE
Sbjct: 1366 ---QLNNNSLLRKRVEYIE 1381



 Score = 66.9 bits (156), Expect = 4e-09
 Identities = 110/595 (18%), Positives = 242/595 (40%), Gaps = 43/595 (7%)

Query: 990  DKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESK 1049
            ++  +++Q Q   Y      ++NK N LLK    E   L QK+    V  +S      S+
Sbjct: 48   EQRKREEQKQGISYYRDLCEQLNKENLLLKSFQIENNELKQKLLLINVE-LSAAQQELSR 106

Query: 1050 LAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKT 1109
            +       +  +  +Q++ +  +D +Q   E     ++ + ++K  K+ + T  +     
Sbjct: 107  IRNQLGSQQPTDRYIQKIQQDNVDLQQQINEQNKYKQKLEAELKFYKDNRFTQTIETQDM 166

Query: 1110 EGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQ 1169
                    I+ M DD   +                +++++   +   ++ Q   L++++Q
Sbjct: 167  NFSQNQRKIKEMEDDIQILISDYSRNQEKLEKALNEQKQQSKYDIDQMKSQIQSLSSQIQ 226

Query: 1170 ECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVD 1229
                +   LE +  EL    ++ +++  QL  K      E+   L TV++L+  I     
Sbjct: 227  GWQQRYQNLEIMKIELENKLIILEKENQQLIGKSSY--RESQANLDTVSQLKDQIYQQFK 284

Query: 1230 QRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTM 1289
            Q     AE+  Q   Q E    K +  L+ +L   E    Q  +S Q    +  N+I  +
Sbjct: 285  QINDLKAEI--QQKQQSEYQLIKEQQNLKQKL---EQSQSQTYNSQQVENTQYVNEIFKL 339

Query: 1290 EQ-VTSLQNKLQDKEEHLRNLQEKYADV----INQIEILRSEIED-EKVAFXXXXXXXXX 1343
            +Q +  LQ + ++      NL +   ++    + Q + + + +E+ E++           
Sbjct: 340  KQYIEQLQYENENYRTQKSNLYQNQTNISSKEVQQNQQINAYLEEIERLKGNIFSLQTQY 399

Query: 1344 XXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVL 1403
                   + R + +  K + ++ +    E N + +               + ND + K+ 
Sbjct: 400  EKQLNDQENRFQIE-LKSVSDKFVSQQKELNCKTQIFEESRFTFQNQQQIQENDIQTKIW 458

Query: 1404 E--------LTHQLELKDSEIYQKTHEYTITLTQRNDEFENVR--QQLVEYEKRIEDLTY 1453
            +        L   L  K  E+  +  +Y    TQ   + + ++  + LVE ++ I    Y
Sbjct: 459  QDKFYEQQTLNEDLMYKHQELRNQLTQYLNYKTQNEYDQKTIQNLEALVEEQQNIMHSLY 518

Query: 1454 EKESELA------ILRLKMHENANHYETMQKESEIERVKL-IEELNVKITESVS-LN--- 1502
            +KE          +L ++ H+  N+      E++I++++L +++L +K+ +  S LN   
Sbjct: 519  QKELHYKDTINQYMLIIEEHQQRNNGVF---ENQIQQLQLQLDQLQIKLRDQESQLNIKS 575

Query: 1503 KQVAELNKALEEEVAKTNEMQT----ALENQEIEIVTLNDEITNLQNMVRASSSK 1553
             +  +L + +E E  + +E ++     L+ ++I I  L  ++ NLQ  +   + K
Sbjct: 576  SKCFDLERQIEVEKLRFSERESLFSQQLKQEKIRIQQLELQVDNLQKDMALQNQK 630


>UniRef50_A7DN60 Cluster: Chromosome segregation ATPase-like protein;
            n=1; Candidatus Nitrosopumilus maritimus SCM1|Rep:
            Chromosome segregation ATPase-like protein - Candidatus
            Nitrosopumilus maritimus SCM1
          Length = 1206

 Score =  126 bits (305), Expect = 4e-27
 Identities = 222/1107 (20%), Positives = 479/1107 (43%), Gaps = 107/1107 (9%)

Query: 474  DVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMI----KV 529
            +++ + K  E  + EL +     + K L EK+ S + ++ +L  E D A K       KV
Sbjct: 142  ELDALKKTYESSQTELQE-----SKKQLEEKIYSQQSELERLRGERDLAKKEAEFESKKV 196

Query: 530  KSNHKL--KLKQMQKTIDNFSK-----VSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQ 582
                +L  K+KQ Q+ +   S+        ++ E  +L E++H    ++  L +++   +
Sbjct: 197  VEQAELEEKIKQQQEELSQLSRDYSVATRKASLEKAKLEEQIHVQQAELERLAQDREETE 256

Query: 583  LHLVDYDSGRM----IESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQ-KY 637
             H +  +  ++    +E  +  +  ++E LA+ R       E +  DL +++ + +Q + 
Sbjct: 257  -HKMSLEKAKLEKMKLEEKIATQQTQLEKLAKDRELLAKKSEQETNDL-EKISLTEQIRA 314

Query: 638  DEVE-DKLA-DISQLQ----SDQVCSEIKSVHLEEQIDALSASKK--ELALVIENLKLDK 689
             E E +K+A D   ++    +D+   E K   L+ ++ A+S  +   E  L  E   L+ 
Sbjct: 315  QEAELEKMAHDYESVKRKATADKAMLEEKIQTLQVELKAISEERSTFEKKLASEKAALE- 373

Query: 690  EQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQT 749
            EQLY     LEN  +   N + N  Q+  DL + L++  AE     +  IN + QSKI+ 
Sbjct: 374  EQLYIQQVQLENLSKS--NSINNE-QQITDLENNLQEKQAE-----IDTINKQHQSKIE- 424

Query: 750  QFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEK 809
            Q   +    +  +  +  E + +K KS   ++E  +    D     ++K  QL   ++E 
Sbjct: 425  QIQSEKIALQNKIQSQQAELDATKSKSSSAKMESQLQSQVD---DYKKKHAQLDDIMKEY 481

Query: 810  QKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISL 869
            Q   S+   ++  L  ++  L       + + +  E E+K   +K Q  L+E Q    SL
Sbjct: 482  QAVMSKSQSEKTALHEKIQTLQAELDATKSKSISPELESKLTLQKEQ--LQEKQAEIYSL 539

Query: 870  SDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLE 929
            +  +QH + L +  +     + +    Q +L +++S    I+ E ++ +  +K+++E  +
Sbjct: 540  T--RQHQSKLEQVQSEKTALQKQLDSKQAELEEIKSK-PTISPELESQLALQKEQLESKQ 596

Query: 930  IEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELN-KMNLEL 988
             E +T  +      K+   + EK     T L+  L+  K  +E L         +  L L
Sbjct: 597  AEIDTITKQ--HQSKLEQVQSEK-----TTLQKLLEVQKAELEELKSKSPSPELESQLAL 649

Query: 989  IDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYES 1048
              + ++ +Q +    T+Q+ ++       L+Q   E IAL  KI   Q      + + +S
Sbjct: 650  QKEQLESKQAEIDTITKQHQSK-------LEQVQSEKIALQNKIEFQQTK----LEEIKS 698

Query: 1049 KLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPK 1108
            K     T    +E ++  + K+ L+SKQ   E+  L ++   ++++++  K   +  +  
Sbjct: 699  K----PTSYPKLESQLA-LQKEQLESKQ--AEIDALTKQHQSKLEQVQSEKTALQKQLES 751

Query: 1109 TEGMI--ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNT 1166
             +  +  I S   P  +    ++               ++ +  +++   +Q +   L  
Sbjct: 752  KQAELDTIQSKSSPKLESQLTLERQELQKKQAEIDALTKQHQSKLEQ---VQSEKTALQN 808

Query: 1167 ELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISS 1226
            +++   +K+ +L++ +        +  E+  QL+SK  +++T      S + +++S  ++
Sbjct: 809  KVKFQQSKLEELKSKSPSSKIESQLTLER-EQLESKQAEIDTITKQYQSKLEQVQSEKTA 867

Query: 1227 AVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKI 1286
              ++  F+ ++L  + +  +   + + E +L +Q    ESK  ++ D++    Q +  +I
Sbjct: 868  LQNKVKFQQSQL--EEIKSKPTSYPELESKLTLQKEQLESKQAEI-DTITKQHQSKLEQI 924

Query: 1287 VTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXX 1346
                + T+LQ ++  +   L+ L  +  +       L  ++  ++ +             
Sbjct: 925  --QSEKTALQKQVNSQHADLKKLTAERKE-------LEKKLSSKQTSLVQSGQEESVDKK 975

Query: 1347 XXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELT 1406
                      +S  +  +   LN     AQ+K++             ++   E  +++  
Sbjct: 976  PSWLSKILGKKSKARPVDPVSLNEKLLQAQIKEAEAGATVTNDLRTQQIKLVE--LMKKR 1033

Query: 1407 HQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKM 1466
             + E K S++     E  I   Q  DE E   Q  V  E+R        E++++ LR K 
Sbjct: 1034 DEAE-KKSQVISPALEKQIQKLQ--DELEKFEQISVLAEQRALKKKESLEAQISSLREKE 1090

Query: 1467 HENANHYETMQKES-EIERV-KLIEELNVKITESV-----SLNKQVAELNKALEEEV-AK 1518
             EN    E++++E  ++E+  +  E+  +K+ E        + ++ A++ + L+ +V  K
Sbjct: 1091 FENKMRMESLEQEKIDLEKSHQDHEDQMIKLAEDEMQIIDQIKREKAQIRRLLQTQVKLK 1150

Query: 1519 TNEMQTALENQEIEIVTLNDEITNLQN 1545
             +  +T+ E QE E+  + D+I  L N
Sbjct: 1151 EHMSKTSAEVQE-ELKEIEDQILFLIN 1176



 Score =  120 bits (290), Expect = 3e-25
 Identities = 207/1088 (19%), Positives = 457/1088 (42%), Gaps = 66/1088 (6%)

Query: 498  VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEI 557
            ++DLI + K    ++  + + I   NK + K    +  +  + + T D       S   I
Sbjct: 13   LEDLIAQNKGDVGRLRHILNSIKN-NKVLAKSDKQYLEEKVEQEYTADETQPPEQSIDFI 71

Query: 558  VRLTEELHHLSQKVAE-LEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAI 616
             +L  E    S ++   L   K    +H  D +    +    Y ++ + ++   T +   
Sbjct: 72   SKLVSEGFGDSNRLRYILHSLKQGKTIHASDKNYLDSVTQSYYAEVAQKKSSESTTVS-- 129

Query: 617  SLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKK 676
            S ++ +      EL  L++ Y+  + +L +  +   +++ S+     LE        +KK
Sbjct: 130  STIDEEHKQKQSELDALKKTYESSQTELQESKKQLEEKIYSQ--QSELERLRGERDLAKK 187

Query: 677  ELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELL 736
            E     E+ K+ ++       +LE   E I  + +   Q + D +    K S EK ++L 
Sbjct: 188  EAEF--ESKKVVEQA------ELE---EKIKQQQEELSQLSRDYSVATRKASLEK-AKLE 235

Query: 737  AKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLE 796
             +I H +Q++++ +   D +  E  + +E  + E  K + +I   +  +  +   R  L 
Sbjct: 236  EQI-HVQQAELE-RLAQDREETEHKMSLEKAKLEKMKLEEKIATQQTQLEKLAKDRELLA 293

Query: 797  RKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLE---IEHENKELQK 853
            +K++Q  + L EK     +   QE EL  ++A   D++ V  K   +   +E + + LQ 
Sbjct: 294  KKSEQETNDL-EKISLTEQIRAQEAEL-EKMA--HDYESVKRKATADKAMLEEKIQTLQV 349

Query: 854  KNQILLEENQNLQISLSDMQQ--HYNALVEKANRTDLAESESTKYQTQLRDLESNLKRIT 911
            + + + EE    +  L+  +        +++    +L++S S   + Q+ DLE+NL+   
Sbjct: 350  ELKAISEERSTFEKKLASEKAALEEQLYIQQVQLENLSKSNSINNEQQITDLENNLQEKQ 409

Query: 912  HEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNI 971
             E  T+  Q + +IE ++ E    +++ I+ ++   +   K+     ++E+QLQ   ++ 
Sbjct: 410  AEIDTINKQHQSKIEQIQSE-KIALQNKIQSQQAELDA-TKSKSSSAKMESQLQSQVDDY 467

Query: 972  ENLNMNVEELNKMNLELIDK-HVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQ 1030
            +  +  ++++ K    ++ K   +K        T Q   +  K  ++  + + ++    +
Sbjct: 468  KKKHAQLDDIMKEYQAVMSKSQSEKTALHEKIQTLQAELDATKSKSISPELESKLTLQKE 527

Query: 1031 KINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQH---NEELQILVRE 1087
            ++   Q    S+   ++SKL Q  ++   +++++     +L + K     + EL+  +  
Sbjct: 528  QLQEKQAEIYSLTRQHQSKLEQVQSEKTALQKQLDSKQAELEEIKSKPTISPELESQLAL 587

Query: 1088 QDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEE 1147
            Q +Q+ E K+ ++     I K       S +E +  +   +             LK +  
Sbjct: 588  QKEQL-ESKQAEID---TITKQH----QSKLEQVQSEKTTLQKLLEVQKAELEELKSKSP 639

Query: 1148 EEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLN 1207
               ++ +  LQ++  +L ++  E  T   Q ++   ++    +  Q +I   ++KLE++ 
Sbjct: 640  SPELESQLALQKE--QLESKQAEIDTITKQHQSKLEQVQSEKIALQNKIEFQQTKLEEIK 697

Query: 1208 TENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQRE------ADFQKTEHELRVQL 1261
            ++  +     ++L       ++ +  EI  L KQH ++ E         QK     + +L
Sbjct: 698  SKPTSYPKLESQLALQ-KEQLESKQAEIDALTKQHQSKLEQVQSEKTALQKQLESKQAEL 756

Query: 1262 SAFESKYEQLLDS-VQSSTQEETNKIVTMEQVTSL-QNKLQDKEEHLRNLQEKYADVINQ 1319
               +SK    L+S +    QE   K   ++ +T   Q+KL+  +     LQ K     ++
Sbjct: 757  DTIQSKSSPKLESQLTLERQELQKKQAEIDALTKQHQSKLEQVQSEKTALQNKVKFQQSK 816

Query: 1320 IEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKK 1379
            +E L+S+    K+                  D  T+    K  Q QS     +   + ++
Sbjct: 817  LEELKSKSPSSKIESQLTLEREQLESKQAEIDTITKQYQSKLEQVQSEKTALQNKVKFQQ 876

Query: 1380 SSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQ 1439
            S              +   E+K+     QLE K +EI   T ++   L Q   E   +++
Sbjct: 877  SQLEEIKSKPTSYPEL---ESKLTLQKEQLESKQAEIDTITKQHQSKLEQIQSEKTALQK 933

Query: 1440 QLVEYEKRIEDLTYEK---ESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKIT 1496
            Q+      ++ LT E+   E +L+  +  + ++       +K S + ++ L ++   +  
Sbjct: 934  QVNSQHADLKKLTAERKELEKKLSSKQTSLVQSGQEESVDKKPSWLSKI-LGKKSKARPV 992

Query: 1497 ESVSLNKQVAELN-KALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQ 1555
            + VSLN+++ +   K  E     TN+++T    Q+I++V L  +    +   +  S  ++
Sbjct: 993  DPVSLNEKLLQAQIKEAEAGATVTNDLRT----QQIKLVELMKKRDEAEKKSQVISPALE 1048

Query: 1556 KHVSFASD 1563
            K +    D
Sbjct: 1049 KQIQKLQD 1056



 Score =  100 bits (239), Expect = 4e-19
 Identities = 165/853 (19%), Positives = 371/853 (43%), Gaps = 80/853 (9%)

Query: 763  YIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDE 822
            Y E  + + S+  +    ++E     +    +L++  +   + LQE +K   E    +  
Sbjct: 114  YAEVAQKKSSESTTVSSTIDEEHKQKQSELDALKKTYESSQTELQESKKQLEEKIYSQQS 173

Query: 823  LVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEK 882
             + RL      +R + K+  E E E+K++ ++ + L E+ +  Q  LS + + Y+    K
Sbjct: 174  ELERLR----GERDLAKK--EAEFESKKVVEQAE-LEEKIKQQQEELSQLSRDYSVATRK 226

Query: 883  ANRTDLAESESTKYQTQLRDLESNLKRITH-----EHQTLIVQKKKEIEDLEIEF---NT 934
            A+       E  K + Q+   ++ L+R+       EH+  + + K E   LE +     T
Sbjct: 227  ASL------EKAKLEEQIHVQQAELERLAQDREETEHKMSLEKAKLEKMKLEEKIATQQT 280

Query: 935  QIESAIRDKKVLNEKYEKNIEYVTQ--LEAQLQEYKNNIENLNMNVEELNKMNLELIDKH 992
            Q+E   +D+++L +K E+    + +  L  Q++  +  +E +  + E + +      DK 
Sbjct: 281  QLEKLAKDRELLAKKSEQETNDLEKISLTEQIRAQEAELEKMAHDYESVKRK--ATADKA 338

Query: 993  VQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQ 1052
            + +++ Q+     + I+E  + +   K+   E  AL +++   QV   ++         Q
Sbjct: 339  MLEEKIQTLQVELKAISE--ERSTFEKKLASEKAALEEQLYIQQVQLENLSKSNSINNEQ 396

Query: 1053 FTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGM 1112
              T LEN  +E Q     +  +KQH  +++ +  E+     +++  +   +    K+   
Sbjct: 397  QITDLENNLQEKQAEIDTI--NKQHQSKIEQIQSEKIALQNKIQSQQAELDATKSKSSSA 454

Query: 1113 IISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECY 1172
             + S ++   DD                 +  + + E    ++ L E+   L  EL    
Sbjct: 455  KMESQLQSQVDDYKKKHAQLDDIMKEYQAVMSKSQSE----KTALHEKIQTLQAELDATK 510

Query: 1173 TKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRG 1232
            +K I  E L ++LT    + +EQ+ + ++++  L  ++ + L  V   ++++   +D + 
Sbjct: 511  SKSISPE-LESKLT----LQKEQLQEKQAEIYSLTRQHQSKLEQVQSEKTALQKQLDSKQ 565

Query: 1233 FEIAELWKQHLAQREAD----FQKTEHELR-VQLSAFESKYEQLLDSVQS--STQEETNK 1285
             E+ E+  +     E +     QK + E +  ++     +++  L+ VQS  +T ++  +
Sbjct: 566  AELEEIKSKPTISPELESQLALQKEQLESKQAEIDTITKQHQSKLEQVQSEKTTLQKLLE 625

Query: 1286 I--VTMEQVTS------LQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXX 1337
            +    +E++ S      L+++L  ++E L + Q +   +  Q +    +++ EK+A    
Sbjct: 626  VQKAELEELKSKSPSPELESQLALQKEQLESKQAEIDTITKQHQSKLEQVQSEKIALQNK 685

Query: 1338 XXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVND 1397
                         +++++  SY +++ Q  L    +  QL+               ++  
Sbjct: 686  IEFQQTKLE----EIKSKPTSYPKLESQLAL----QKEQLESKQAEIDALTKQHQSKLEQ 737

Query: 1398 AEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKES 1457
             +++   L  QLE K +E+     + +  L     +    RQ+L + +  I+ LT + +S
Sbjct: 738  VQSEKTALQKQLESKQAELDTIQSKSSPKL---ESQLTLERQELQKKQAEIDALTKQHQS 794

Query: 1458 ELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVA 1517
                   K+ +  +    +Q + + ++ KL EEL  K   S    K  ++L    E+  +
Sbjct: 795  -------KLEQVQSEKTALQNKVKFQQSKL-EELKSKSPSS----KIESQLTLEREQLES 842

Query: 1518 KTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMN 1577
            K  E+ T  +  + ++  +  E T LQN V+   S++++  S  +   +  + +L  T+ 
Sbjct: 843  KQAEIDTITKQYQSKLEQVQSEKTALQNKVKFQQSQLEEIKSKPTSYPE-LESKL--TLQ 899

Query: 1578 KELLDAVPRAELD 1590
            KE L++  +AE+D
Sbjct: 900  KEQLES-KQAEID 911



 Score = 98.7 bits (235), Expect = 1e-18
 Identities = 187/1035 (18%), Positives = 428/1035 (41%), Gaps = 78/1035 (7%)

Query: 215  KQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKL 274
            +++++++  ++     +   EK +L + I    V+ + LE   +  E    ++SLE +KL
Sbjct: 210  QEELSQLSRDYSVATRKASLEKAKLEEQIH---VQQAELERLAQDREETEHKMSLEKAKL 266

Query: 275  AQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSL--EI-ANMTELTKKIELL 331
             +   +                ++ +    E++T   EK SL  +I A   EL K     
Sbjct: 267  EKMKLEEKIATQQTQLEKLAKDRELLAKKSEQETNDLEKISLTEQIRAQEAELEKMAHDY 326

Query: 332  EHLNCQIRQTNKELENKLATMGTESKAVSSP-SKKGSPLISRKSGRNTASKMKSPWSQLS 390
            E +  +       LE K+ T+  E KA+S   S     L S K+       ++    +  
Sbjct: 327  ESVKRKATADKAMLEEKIQTLQVELKAISEERSTFEKKLASEKAALEEQLYIQQVQLENL 386

Query: 391  SETLNQDTDKKIN--KNEIAKLEMVIQSLNKDLVDK-EYVISEKDTXXXXXXXXXXGKDT 447
            S++ + + +++I   +N + + +  I ++NK    K E + SEK              D 
Sbjct: 387  SKSNSINNEQQITDLENNLQEKQAEIDTINKQHQSKIEQIQSEKIALQNKIQSQQAELDA 446

Query: 448  L-----IAQLQLEHQQHMEGPSLIHVGTNT--EDVNEIAKVQEQLKQELNDEIKDVNVKD 500
                   A+++ + Q  ++     H   +   ++   +    +  K  L+++I+ +  + 
Sbjct: 447  TKSKSSSAKMESQLQSQVDDYKKKHAQLDDIMKEYQAVMSKSQSEKTALHEKIQTLQAEL 506

Query: 501  LIEKLKSA----EEQITQLNDEIDAANKNMIKVKSNHKLKLKQ-------MQKTIDNFSK 549
               K KS     E ++T   +++      +  +   H+ KL+Q       +QK +D+   
Sbjct: 507  DATKSKSISPELESKLTLQKEQLQEKQAEIYSLTRQHQSKLEQVQSEKTALQKQLDSKQA 566

Query: 550  VSDSNKEIVRLTEELH-HLSQKVAELEEEKGNLQLHLVDYDSG-RMIESD--VYKKMIEM 605
              +  K    ++ EL   L+ +  +LE ++  +      + S    ++S+    +K++E+
Sbjct: 567  ELEEIKSKPTISPELESQLALQKEQLESKQAEIDTITKQHQSKLEQVQSEKTTLQKLLEV 626

Query: 606  ENLAETRLKAISL---LESQKFDLVQELHILQQKYDEV-EDKLADISQLQSDQVCSEIKS 661
            +      LK+ S    LESQ     ++L   Q + D + +   + + Q+QS+++  + K 
Sbjct: 627  QKAELEELKSKSPSPELESQLALQKEQLESKQAEIDTITKQHQSKLEQVQSEKIALQNKI 686

Query: 662  VHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLT 721
               + +++ + +       +   L L KEQL     +++   +   +KL+    E   L 
Sbjct: 687  EFQQTKLEEIKSKPTSYPKLESQLALQKEQLESKQAEIDALTKQHQSKLEQVQSEKTALQ 746

Query: 722  DKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRL 781
             +LE   AE     L  I  +   K+++Q  ++   QE       I++   +++S++ ++
Sbjct: 747  KQLESKQAE-----LDTIQSKSSPKLESQLTLER--QELQKKQAEIDALTKQHQSKLEQV 799

Query: 782  EESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQL 841
            +     ++++    + K ++L S      K  S+ T++ ++L ++ A             
Sbjct: 800  QSEKTALQNKVKFQQSKLEELKSK-SPSSKIESQLTLEREQLESKQA------------- 845

Query: 842  LEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLR 901
             EI+   K+ Q K + +  E   LQ  +   Q     +  K       ES+ T  + QL 
Sbjct: 846  -EIDTITKQYQSKLEQVQSEKTALQNKVKFQQSQLEEIKSKPTSYPELESKLTLQKEQLE 904

Query: 902  DLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQ---IESAIRDKKVLNEKYEKNIEYVT 958
              ++ +  IT +HQ+ + Q + E   L+ + N+Q   ++    ++K L +K       + 
Sbjct: 905  SKQAEIDTITKQHQSKLEQIQSEKTALQKQVNSQHADLKKLTAERKELEKKLSSKQTSLV 964

Query: 959  Q--LEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNA 1016
            Q   E  + +  + +  +     +   ++   +++ + + Q +  +      N+      
Sbjct: 965  QSGQEESVDKKPSWLSKILGKKSKARPVDPVSLNEKLLQAQIKEAEAGATVTND------ 1018

Query: 1017 LLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQ 1076
             L+ +  +++ L +K + A+     +    E ++ +   +LE  E+      ++ L  K+
Sbjct: 1019 -LRTQQIKLVELMKKRDEAEKKSQVISPALEKQIQKLQDELEKFEQISVLAEQRALKKKE 1077

Query: 1077 HNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXX 1136
              E     +RE++ + K   E+    ++++ K+        I+   D+   +D       
Sbjct: 1078 SLEAQISSLREKEFENKMRMESLEQEKIDLEKSHQDHEDQMIKLAEDEMQIIDQIKREKA 1137

Query: 1137 XXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTEL-TGHDVVNQEQ 1195
                 L+ Q     ++ +  + + SA++  EL+E   +I+ L     E     DV+  + 
Sbjct: 1138 QIRRLLQTQ-----VKLKEHMSKTSAEVQEELKEIEDQILFLINRQAEKPLSTDVI--KS 1190

Query: 1196 INQLKSKLEQLNTEN 1210
            +  L  KL ++ ++N
Sbjct: 1191 LESLNDKLNEVLSKN 1205



 Score = 85.8 bits (203), Expect = 9e-15
 Identities = 123/675 (18%), Positives = 293/675 (43%), Gaps = 59/675 (8%)

Query: 951  EKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQS--PDYTEQYI 1008
            E++I+++++L ++     N +  +  ++++   ++    DK+     TQS   +  ++  
Sbjct: 65   EQSIDFISKLVSEGFGDSNRLRYILHSLKQGKTIHAS--DKNYLDSVTQSYYAEVAQKKS 122

Query: 1009 NEINKLNALL----KQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEM 1064
            +E   +++ +    KQK  E+ AL +   ++Q          E K+    ++LE +  E 
Sbjct: 123  SESTTVSSTIDEEHKQKQSELDALKKTYESSQTELQESKKQLEEKIYSQQSELERLRGER 182

Query: 1065 QRVSKQL-LDSKQHNE--ELQILVREQDDQIKELKE--TKLTFEMNIPKTEGMIISSTIE 1119
                K+   +SK+  E  EL+  +++Q +++ +L    +  T + ++ K +   +   I 
Sbjct: 183  DLAKKEAEFESKKVVEQAELEEKIKQQQEELSQLSRDYSVATRKASLEKAK---LEEQIH 239

Query: 1120 PMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLE 1179
                +   +              K + E+  ++E+   Q+   +   + +E   K  + E
Sbjct: 240  VQQAELERLAQDREETEHKMSLEKAKLEKMKLEEKIATQQTQLEKLAKDRELLAKKSEQE 299

Query: 1180 TLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELW 1239
            T + E     +   EQI   +++LE++  + +++     + +++   A+ +   +  ++ 
Sbjct: 300  TNDLE----KISLTEQIRAQEAELEKMAHDYESV-----KRKATADKAMLEEKIQTLQVE 350

Query: 1240 KQHLAQREADFQKTEHELRVQLSAFESKYEQL-LDSVQSSTQEETNKIVTMEQVTSLQNK 1298
             + +++  + F+K   +L  + +A E   EQL +  VQ     ++N I   +Q+T L+N 
Sbjct: 351  LKAISEERSTFEK---KLASEKAALE---EQLYIQQVQLENLSKSNSINNEQQITDLENN 404

Query: 1299 LQDKEEHLRNLQEKYADVINQIE----ILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRT 1354
            LQ+K+  +  + +++   I QI+     L+++I+ ++                     + 
Sbjct: 405  LQEKQAEIDTINKQHQSKIEQIQSEKIALQNKIQSQQAELDATKSKSSSAKMESQLQSQV 464

Query: 1355 ENQSYKQMQEQSIL---------NINEENAQLKKSSXXXXXXXXXXXXRVN-DAEAKVLE 1404
            ++   K  Q   I+         + +E+ A  +K               ++ + E+K+  
Sbjct: 465  DDYKKKHAQLDDIMKEYQAVMSKSQSEKTALHEKIQTLQAELDATKSKSISPELESKLTL 524

Query: 1405 LTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIED------LTYEKESE 1458
               QL+ K +EIY  T ++   L Q   E   +++QL   +  +E+      ++ E ES+
Sbjct: 525  QKEQLQEKQAEIYSLTRQHQSKLEQVQSEKTALQKQLDSKQAELEEIKSKPTISPELESQ 584

Query: 1459 LAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAK 1518
            LA+ + ++       +T+ K+    + KL +  + K T    L  Q AEL +   +  + 
Sbjct: 585  LALQKEQLESKQAEIDTITKQ---HQSKLEQVQSEKTTLQKLLEVQKAELEELKSKSPSP 641

Query: 1519 TNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNK 1578
              E Q AL+ +++E  +   EI  +    ++   ++Q       +  + +  +L+   +K
Sbjct: 642  ELESQLALQKEQLE--SKQAEIDTITKQHQSKLEQVQSEKIALQNKIEFQQTKLEEIKSK 699

Query: 1579 ELLDAVPRAELDLAM 1593
                + P+ E  LA+
Sbjct: 700  P--TSYPKLESQLAL 712


>UniRef50_A0DA04 Cluster: Chromosome undetermined scaffold_42, whole
            genome shotgun sequence; n=2; Paramecium tetraurelia|Rep:
            Chromosome undetermined scaffold_42, whole genome shotgun
            sequence - Paramecium tetraurelia
          Length = 1357

 Score =  126 bits (304), Expect = 5e-27
 Identities = 238/1186 (20%), Positives = 500/1186 (42%), Gaps = 120/1186 (10%)

Query: 474  DVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAA---NKNMIKVK 530
            +  ++ +  +Q+K+ L D++    +K+  E+++  ++ I +LN ++D +   N+ +++  
Sbjct: 97   EFQQLLRDNQQMKKTL-DQMNQ-QIKEYEEEIQRQKQVIDRLNFDLDKSKRDNEQLLQAL 154

Query: 531  SNHKLK-LKQMQKTI-DNF---SKVSDSNKEIVRLTEELHHL---SQKVAELEEEKGNLQ 582
            ++ K + L Q Q  + DN    S +   N ++  L +E++ L   + K   +++E    Q
Sbjct: 155  NDIKQRGLSQEQSLLQDNQRMKSTIDSLNNDLRSLQQEIYRLKSINDKSRYVQDESNRYQ 214

Query: 583  L-HLVDYDSGRMIESDVYKKMIEMENLAETRLKAIS-------LLESQKFDLVQELHILQ 634
              +  +    R +E  +   M + E+      +A         LL+ Q   L Q+LH++Q
Sbjct: 215  QENQANLARIRQLEMQIRDLMSKEESYQLQITRAAQGTNTENQLLKDQIAQLNQQLHMMQ 274

Query: 635  QKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKK---ELALVIENLKLDKEQ 691
            ++Y +   +L D+ Q Q   +  +  +++++ +       +K   E   ++  ++L K+Q
Sbjct: 275  KQYQK---QLDDVRQDQDRMISEQRNTINIQIKDQLQRDQQKWMDEREALLHEIQLLKQQ 331

Query: 692  LYGTIKDLENDK---EDIMNKLQNYI----QENMDLTDKLEKMSAEKISELLAKINHEEQ 744
            L      +   +   ED  NK Q +I    Q N  L +KL  +  +       K+ +++ 
Sbjct: 332  LAQNELQVTRKRQLLEDEANKNQQFIVEMEQANGQLQNKLRDLQMQLQQSEKDKMRNDQY 391

Query: 745  SKIQTQFGIDAKIQERDLY-----IENIESELSKYKSRICRLEESIAVMEDRR----YSL 795
             +   +  +  +  +R LY       N+ S+  + K +I +L   + V +D       +L
Sbjct: 392  VRKIDELQLQVEQLQRQLYDLTSKYNNLLSQYEQKKYQIDQLNGQLNVSQDNEKQKIMNL 451

Query: 796  ERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKN 855
            ER+  +L   L + Q+   +   Q +E  + L +   +    +KQL E +   +EL    
Sbjct: 452  ERQIRELQDQLADTQRLRQQLH-QMNENYSALQITFKNS---QKQLSEADELRQELDALF 507

Query: 856  QILLEENQNLQISLSDMQQHYNALV---EKANRTDLAESESTKYQTQ-----LRDLESNL 907
            Q L    Q    S  D+ ++   L+    K ++    E E  + Q Q     L + ++  
Sbjct: 508  QELEYYKQQDMKSKQDLDRYKQQLIIIENKHSQQSNYEIEKLRQQNQQLIDELNEWKNRN 567

Query: 908  KRITHEHQTLIVQKKKEIEDLEIE--FNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQ 965
            K++  + Q  IV   +   DL+     N + + A+ +   L  K ++ ++ +  LE +L 
Sbjct: 568  KQLEGKLQQQIVMLNQAQNDLQAHQALNEKQQYALNESNQLRVKIKELLDQIQYLEMELN 627

Query: 966  EYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEI 1025
            +  N I++L +++++ +K    LI    +K+     D+ E  I ++ K  A L     + 
Sbjct: 628  KKDNLIQDLQISLDQFSKQRDSLIIIEKEKK-----DF-EYRIIQLEKQLAELTMYKTQF 681

Query: 1026 IALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILV 1085
              L  K NN    Y S+  DYE  L ++  K + +  +  +  KQ+  + Q N E++ L 
Sbjct: 682  QDLQFKYNNLGQEYESLRKDYE--LLRY--KYDEINNQYIQSKKQI--NIQINSEVEALK 735

Query: 1086 REQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQ 1145
             E    I + K    T+E  I       + STI    +     +                
Sbjct: 736  SEIQTWIIKCK----TYESEIS-----FLRSTINDYQEIEQESEMLKQELETWQIKF-AD 785

Query: 1146 EEEEFIQERSVLQEQSAKLNTELQECYTKIIQLE-TLNTELTGHDVVNQEQ--INQLKSK 1202
             + E IQ R  +QE   K    + E   +I   +  L +     D   Q+   + Q + +
Sbjct: 786  ADRERIQLRQSIQEYE-KFKFRISELEREISNYKYKLESTEKERDGARQQLTILQQQRVQ 844

Query: 1203 LEQLNTENDNLLSTVAEL-RSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQL 1261
             EQ+  E D+L+    E  R ++S   +        +  Q L Q+    ++ + +L  ++
Sbjct: 845  FEQIKKEYDSLVYKFQEQERDNLSLRNEIENLRQQLISLQQLKQQLILIEQEKSQLLYKI 904

Query: 1262 SAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQ-I 1320
              F+ + + L   + S+   +        +   L+ KL+  +  +  ++++     NQ I
Sbjct: 905  EEFDRERQLLKQQISSANNIKMESESLKREYEMLRMKLESSDREISTMRQQLTLASNQKI 964

Query: 1321 EI--LRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLK 1378
            E   LRSE +  +++F                 +  +N+  +  +E  ++ +  E ++ +
Sbjct: 965  EFDRLRSEYQQLRMSFEDSEREKQGLKQQLQIGINVKNELEQFRKEYDLIRLKFEESEKE 1024

Query: 1379 KSSXXXXXXXXXXXXRVNDAEAKVLELTHQL-ELKDSEIYQKTHEYTITLTQRNDEFENV 1437
            K+              VN  + ++ +L+ Q+ + +  E+  K             E E +
Sbjct: 1025 KNQLRIQYQSSQS--NVNGYKIQIEQLSSQINQFQSQELVMKR------------EIEML 1070

Query: 1438 RQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQ-KESEIERVKLIEELNVKIT 1496
             QQ+  Y+K        K+ ++   + K  E    YE +Q K+  I+    ++ L  +I 
Sbjct: 1071 IQQIDVYKKD----QINKQQQIQEYQFKYQEIMKEYENLQGKQKNID----VDALMYEIY 1122

Query: 1497 ESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQK 1556
            E   L KQ+A+ +K  E E  + NE +  +E + ++I  L  EI  L     +  +++++
Sbjct: 1123 E---LKKQLAQKDKQYEYERQEINEQKFQME-KSVKI-RLEQEIRILNEKFNSELNELRR 1177

Query: 1557 HVSFASDTKQGRDEQLDNTMNKELL----DAVPRAELDLAMYMLHQ 1598
             +      K   + +L     ++++       P  ++D  MY + +
Sbjct: 1178 QIQIEKQEKLKLESELRIKYEQQIMQLQQQIKPSVDVDALMYEIFE 1223



 Score =  111 bits (267), Expect = 2e-22
 Identities = 195/975 (20%), Positives = 421/975 (43%), Gaps = 102/975 (10%)

Query: 685  LKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQ 744
            ++ + E L G I  L+      + + Q  +++N  +   L++M+ ++I E   +I  ++Q
Sbjct: 73   IERENEILKGEIAKLQQFANSKVPEFQQLLRDNQQMKKTLDQMN-QQIKEYEEEIQRQKQ 131

Query: 745  SKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGS 804
               +  F +D   ++     E +   L+  K R    E+S+  ++D +  ++   D L +
Sbjct: 132  VIDRLNFDLDKSKRDN----EQLLQALNDIKQRGLSQEQSL--LQDNQ-RMKSTIDSLNN 184

Query: 805  YLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENK---------ELQKKN 855
             L+  Q        QE   + RL  + D  R V+ +    + EN+         E+Q ++
Sbjct: 185  DLRSLQ--------QE---IYRLKSINDKSRYVQDESNRYQQENQANLARIRQLEMQIRD 233

Query: 856  QILLEENQNLQISLSDMQQHY-NALVEK--ANRTDLAESESTKYQTQLRDLESNLKR-IT 911
             +  EE+  LQI+ +    +  N L++   A           +YQ QL D+  +  R I+
Sbjct: 234  LMSKEESYQLQITRAAQGTNTENQLLKDQIAQLNQQLHMMQKQYQKQLDDVRQDQDRMIS 293

Query: 912  HEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNI 971
             +  T+ +Q K +++  + ++  + E+ + + ++L ++  +N   VT+    L++  N  
Sbjct: 294  EQRNTINIQIKDQLQRDQQKWMDEREALLHEIQLLKQQLAQNELQVTRKRQLLEDEANKN 353

Query: 972  ENLNMNVEELN-KMNLELIDKHVQKQQTQSPDY-TEQYINEINKLNALLKQKDEEIIALN 1029
            +   + +E+ N ++  +L D  +Q QQ++      +QY+ +I++L   ++Q   ++  L 
Sbjct: 354  QQFIVEMEQANGQLQNKLRDLQMQLQQSEKDKMRNDQYVRKIDELQLQVEQLQRQLYDLT 413

Query: 1030 QKINNAQVSYMSMVSDYESKLAQFTT-------KLENMEEEMQRVSKQLLDSK------- 1075
             K NN    Y       +    Q          K+ N+E +++ +  QL D++       
Sbjct: 414  SKYNNLLSQYEQKKYQIDQLNGQLNVSQDNEKQKIMNLERQIRELQDQLADTQRLRQQLH 473

Query: 1076 QHNEE---LQILVREQDDQIKELKETK-----LTFEMNIPKTEGMIISSTIEPMSDDANN 1127
            Q NE    LQI  +    Q+ E  E +     L  E+   K + M     ++        
Sbjct: 474  QMNENYSALQITFKNSQKQLSEADELRQELDALFQELEYYKQQDMKSKQDLDRYKQQLII 533

Query: 1128 VDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTG 1187
            ++               Q+ ++ I E +  + ++ +L  +LQ+   +I+ L     +L  
Sbjct: 534  IENKHSQQSNYEIEKLRQQNQQLIDELNEWKNRNKQLEGKLQQ---QIVMLNQAQNDLQA 590

Query: 1188 HDVVNQEQ------INQLKSKLEQLNTENDNL---LSTVAELRSSISSAVDQRGFEIAEL 1238
            H  +N++Q       NQL+ K+++L  +   L   L+    L   +  ++DQ   +   L
Sbjct: 591  HQALNEKQQYALNESNQLRVKIKELLDQIQYLEMELNKKDNLIQDLQISLDQFSKQRDSL 650

Query: 1239 WKQHLAQREADFQKTEHELRV-QLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQN 1297
                  +++ +++  + E ++ +L+ ++++++ L     +  QE  +     E +    +
Sbjct: 651  IIIEKEKKDFEYRIIQLEKQLAELTMYKTQFQDLQFKYNNLGQEYESLRKDYELLRYKYD 710

Query: 1298 KLQDKEEHLRNLQEKYADVINQIEILRSEIED--EKVAFXXXXXXXXXXXXXXXXDLRTE 1355
            ++ +  +++++ ++    + +++E L+SEI+    K                   ++  E
Sbjct: 711  EINN--QYIQSKKQINIQINSEVEALKSEIQTWIIKCKTYESEISFLRSTINDYQEIEQE 768

Query: 1356 NQSYKQMQEQ---SILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELK 1412
            ++  KQ  E       + + E  QL++S             R+++ E ++    ++LE  
Sbjct: 769  SEMLKQELETWQIKFADADRERIQLRQS----IQEYEKFKFRISELEREISNYKYKLEST 824

Query: 1413 DSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANH 1472
            + E      + TI L Q+  +FE +++   EY+  +     E+E +   LR ++      
Sbjct: 825  EKERDGARQQLTI-LQQQRVQFEQIKK---EYDSLVYKF-QEQERDNLSLRNEIENLRQQ 879

Query: 1473 YETMQKES------EIERVKLIEELNVKITESVSLNKQVAELN--KALEEEVAKTNEM-Q 1523
              ++Q+        E E+ +L+ ++     E   L +Q++  N  K   E + +  EM +
Sbjct: 880  LISLQQLKQQLILIEQEKSQLLYKIEEFDRERQLLKQQISSANNIKMESESLKREYEMLR 939

Query: 1524 TALENQEIEIVTLNDEITNLQNMV----RASSSKIQKHVSF--ASDTKQGRDEQLDNTMN 1577
              LE+ + EI T+  ++T   N      R  S   Q  +SF  +   KQG  +QL   +N
Sbjct: 940  MKLESSDREISTMRQQLTLASNQKIEFDRLRSEYQQLRMSFEDSEREKQGLKQQLQIGIN 999

Query: 1578 -KELLDAVPRAELDL 1591
             K  L+   R E DL
Sbjct: 1000 VKNELEQF-RKEYDL 1013



 Score =  107 bits (256), Expect = 3e-21
 Identities = 171/902 (18%), Positives = 381/902 (42%), Gaps = 76/902 (8%)

Query: 476  NEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKL 535
            N++  +Q QL+Q   D++++      I++L+   EQ+ +   ++ +   N++      K 
Sbjct: 369  NKLRDLQMQLQQSEKDKMRNDQYVRKIDELQLQVEQLQRQLYDLTSKYNNLLSQYEQKKY 428

Query: 536  KLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIE 595
            ++ Q+   + N S+ ++  K I+ L  ++  L  ++A+ +  +  L     +Y + ++  
Sbjct: 429  QIDQLNGQL-NVSQDNEKQK-IMNLERQIRELQDQLADTQRLRQQLHQMNENYSALQITF 486

Query: 596  SDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQV 655
             +  K++ E + L   R +  +L +  ++   Q++   +Q  D  + +L  I    S Q 
Sbjct: 487  KNSQKQLSEADEL---RQELDALFQELEYYKQQDMKS-KQDLDRYKQQLIIIENKHSQQS 542

Query: 656  CSEIKSVHLEEQ--IDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNY 713
              EI+ +  + Q  ID L+  K     +   L+     L     DL+      +N+ Q Y
Sbjct: 543  NYEIEKLRQQNQQLIDELNEWKNRNKQLEGKLQQQIVMLNQAQNDLQ--AHQALNEKQQY 600

Query: 714  -IQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELS 772
             + E+  L  K++++  ++I  L  ++N ++      Q  +D   ++RD  I  IE E  
Sbjct: 601  ALNESNQLRVKIKEL-LDQIQYLEMELNKKDNLIQDLQISLDQFSKQRDSLII-IEKEKK 658

Query: 773  KYKSRICRLEESIAVM---EDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLA- 828
             ++ RI +LE+ +A +   + +   L+ K + LG   +  +K Y     + DE+ N+   
Sbjct: 659  DFEYRIIQLEKQLAELTMYKTQFQDLQFKYNNLGQEYESLRKDYELLRYKYDEINNQYIQ 718

Query: 829  ----VLMDHDRVVEKQLLEIE--------------------HENKELQKKNQILLEENQN 864
                + +  +  VE    EI+                    ++ +E+++++++L +E + 
Sbjct: 719  SKKQINIQINSEVEALKSEIQTWIIKCKTYESEISFLRSTINDYQEIEQESEMLKQELET 778

Query: 865  LQISLSDMQQHYNALVEKAN-------RTDLAESESTKYQTQLRDLESNLKRITHEHQTL 917
             QI  +D  +    L +          R    E E + Y+ +L   E   +    +  T+
Sbjct: 779  WQIKFADADRERIQLRQSIQEYEKFKFRISELEREISNYKYKLESTEKE-RDGARQQLTI 837

Query: 918  IVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMN 977
            + Q++ + E ++ E+++ +    ++++  N      IE + Q    LQ+ K  +  +   
Sbjct: 838  LQQQRVQFEQIKKEYDSLVYK-FQEQERDNLSLRNEIENLRQQLISLQQLKQQLILIEQE 896

Query: 978  VEELNKMNLELIDKHVQ--KQQTQSPDY----TEQYINEINKLNALLKQKDEEIIALNQK 1031
              +L    +E  D+  Q  KQQ  S +     +E    E   L   L+  D EI  + Q+
Sbjct: 897  KSQL-LYKIEEFDRERQLLKQQISSANNIKMESESLKREYEMLRMKLESSDREISTMRQQ 955

Query: 1032 I---NNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLL-------DSKQHNEEL 1081
            +   +N ++ +  + S+Y+    Q     E+ E E Q + +QL        + +Q  +E 
Sbjct: 956  LTLASNQKIEFDRLRSEYQ----QLRMSFEDSEREKQGLKQQLQIGINVKNELEQFRKEY 1011

Query: 1082 QILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXX 1141
             ++  + ++  KE  + ++ ++ +     G  I   IE +S   N               
Sbjct: 1012 DLIRLKFEESEKEKNQLRIQYQSSQSNVNGYKIQ--IEQLSSQINQFQSQELVMKREIEM 1069

Query: 1142 LKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQ--EQINQL 1199
            L +Q+ + + +++   Q+Q  +   + QE   +   L+     +    ++ +  E   QL
Sbjct: 1070 L-IQQIDVYKKDQINKQQQIQEYQFKYQEIMKEYENLQGKQKNIDVDALMYEIYELKKQL 1128

Query: 1200 KSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRV 1259
              K +Q   E   +     ++  S+   ++Q    + E +   L +     Q  + E   
Sbjct: 1129 AQKDKQYEYERQEINEQKFQMEKSVKIRLEQEIRILNEKFNSELNELRRQIQIEKQEKLK 1188

Query: 1260 QLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQ 1319
              S    KYEQ +  +Q   +   +    M ++  L+ +   KE+ +  ++++   +  Q
Sbjct: 1189 LESELRIKYEQQIMQLQQQIKPSVDVDALMYEIFELKKQAVTKEQVIEQMKKEQYQLRVQ 1248

Query: 1320 IE 1321
            +E
Sbjct: 1249 ME 1250



 Score =  104 bits (249), Expect = 2e-20
 Identities = 244/1285 (18%), Positives = 550/1285 (42%), Gaps = 125/1285 (9%)

Query: 99   KQKEILMEKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNAL 158
            +QK+++ +++    + SKR +  +++                L D   + +TI   +N L
Sbjct: 128  RQKQVI-DRLNFDLDKSKRDNEQLLQALNDIKQRGLSQEQSLLQDNQRMKSTIDSLNNDL 186

Query: 159  SVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQM 218
              LQ ++  +++ I D    + ++    + +N+A                   E  + Q+
Sbjct: 187  RSLQQEIYRLKS-INDKSRYVQDESNRYQQENQANLARIRQLEMQIRDLMSKEESYQLQI 245

Query: 219  TKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSL-----EEANKLLEAARFEISLEHSK 273
            T+  +         KD+  +L + +     +         ++ ++++   R  I+++   
Sbjct: 246  TRAAQGTNTENQLLKDQIAQLNQQLHMMQKQYQKQLDDVRQDQDRMISEQRNTINIQIKD 305

Query: 274  LAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEH 333
              Q  +Q              L KQ +    + + ++  K  L       L  +    + 
Sbjct: 306  QLQRDQQKWMDEREALLHEIQLLKQQL---AQNELQVTRKRQL-------LEDEANKNQQ 355

Query: 334  LNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSET 393
               ++ Q N +L+NKL  +  + +  S   K  +    RK       +++    QL  + 
Sbjct: 356  FIVEMEQANGQLQNKLRDLQMQLQQ-SEKDKMRNDQYVRK-----IDELQLQVEQLQRQL 409

Query: 394  LNQDTDKKINKNEIAKLEMVIQSLNKDL-VDKEYVISEKDTXXXXXXXXXXGKDTLIAQL 452
             +  +      ++  + +  I  LN  L V ++   +EK             +D L    
Sbjct: 410  YDLTSKYNNLLSQYEQKKYQIDQLNGQLNVSQD---NEKQKIMNLERQIRELQDQLADTQ 466

Query: 453  QLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQI 512
            +L  Q H    +   +    ++  +     ++L+QEL+   +++      + +KS ++  
Sbjct: 467  RLRQQLHQMNENYSALQITFKNSQKQLSEADELRQELDALFQELEYYKQ-QDMKSKQDLD 525

Query: 513  TQLNDEIDAANKNMIKVKSNHKL-KLKQM-QKTIDNFSKVSDSNKEIVRLTEELHHLSQK 570
                  I   NK+    +SN+++ KL+Q  Q+ ID  ++  + NK++         L Q+
Sbjct: 526  RYKQQLIIIENKH--SQQSNYEIEKLRQQNQQLIDELNEWKNRNKQLEG------KLQQQ 577

Query: 571  VAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQEL 630
            +  L + + +LQ H    +  +   ++  +  ++++ L + +++ + +  ++K +L+Q+L
Sbjct: 578  IVMLNQAQNDLQAHQALNEKQQYALNESNQLRVKIKELLD-QIQYLEMELNKKDNLIQDL 636

Query: 631  HILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASK---KELALVIENLKL 687
             I   ++ +  D L  I + + D    E + + LE+Q+  L+  K   ++L     NL  
Sbjct: 637  QISLDQFSKQRDSLIIIEKEKKD---FEYRIIQLEKQLAELTMYKTQFQDLQFKYNNLGQ 693

Query: 688  DKEQLYGTIKDLENDKEDIMNK-LQNYIQENMDLTDKLEKMSAEKISELL-AKINHEEQS 745
            + E L    + L    ++I N+ +Q+  Q N+ +  ++E + +E  + ++  K    E S
Sbjct: 694  EYESLRKDYELLRYKYDEINNQYIQSKKQINIQINSEVEALKSEIQTWIIKCKTYESEIS 753

Query: 746  KIQTQFGIDAKI-QERDLYIENIESELSKY----KSRICRLEESIAVMEDRRYSLERKAD 800
             +++      +I QE ++  + +E+   K+    + RI +L +SI   E  ++ +     
Sbjct: 754  FLRSTINDYQEIEQESEMLKQELETWQIKFADADRERI-QLRQSIQEYEKFKFRISELER 812

Query: 801  QLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLE 860
            ++ +Y     K   E T +E +   +   ++   RV   Q  +I+ E   L  K Q    
Sbjct: 813  EISNY-----KYKLESTEKERDGARQQLTILQQQRV---QFEQIKKEYDSLVYKFQEQER 864

Query: 861  ENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQ 920
            +N +L+  + +++Q   +L +   +  L E E ++   ++ + +        E Q L+ Q
Sbjct: 865  DNLSLRNEIENLRQQLISLQQLKQQLILIEQEKSQLLYKIEEFD-------RERQ-LLKQ 916

Query: 921  KKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQL---QEYKNNIENLNMN 977
            +     ++++E     ES  R+ ++L  K E +   ++ +  QL      K   + L   
Sbjct: 917  QISSANNIKMES----ESLKREYEMLRMKLESSDREISTMRQQLTLASNQKIEFDRLRSE 972

Query: 978  VEELNKMNLELIDKHVQ--KQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNA 1035
             ++L +M+ E  ++  Q  KQQ Q     +  + +  K   L++ K EE      ++   
Sbjct: 973  YQQL-RMSFEDSEREKQGLKQQLQIGINVKNELEQFRKEYDLIRLKFEESEKEKNQLRIQ 1031

Query: 1036 QVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKEL 1095
              S  S V+ Y+ ++ Q ++++ N  +  + V K+ ++     +++ +  ++Q ++ +++
Sbjct: 1032 YQSSQSNVNGYKIQIEQLSSQI-NQFQSQELVMKREIEMLI--QQIDVYKKDQINKQQQI 1088

Query: 1096 KETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERS 1155
            +E +  ++  + + E +      + +  DA   +             + + E + I E+ 
Sbjct: 1089 QEYQFKYQEIMKEYENL--QGKQKNIDVDALMYEIYELKKQLAQKDKQYEYERQEINEQK 1146

Query: 1156 VLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQIN-QLKSKLE-QLNTENDN- 1212
               E+S K+  E QE   +I+  E  N+EL  +++  Q QI  Q K KLE +L  + +  
Sbjct: 1147 FQMEKSVKIRLE-QEI--RILN-EKFNSEL--NELRRQIQIEKQEKLKLESELRIKYEQQ 1200

Query: 1213 LLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREA--DFQKTEHELRVQLSA------- 1263
            ++    +++ S+   VD   +EI EL KQ + + +     +K +++LRVQ+         
Sbjct: 1201 IMQLQQQIKPSVD--VDALMYEIFELKKQAVTKEQVIEQMKKEQYQLRVQMEQRYNEQKL 1258

Query: 1264 -FESKYEQLLD-----SVQSSTQEETNKIVTME--------QVTSLQNKLQDKEE---HL 1306
             FES+    L+     S++S  + +       E        Q+   ++  Q ++E   HL
Sbjct: 1259 QFESEIRMKLERELRISIESDLRYQIENEYNFESNIQDYVLQIEKWKSVCQMRDEEIAHL 1318

Query: 1307 RNLQEKYADVINQ----IEILRSEI 1327
            R LQ+   + +NQ    IE LR+++
Sbjct: 1319 RGLQQALKEKLNQYTSEIESLRTQL 1343



 Score = 41.5 bits (93), Expect = 0.19
 Identities = 95/501 (18%), Positives = 206/501 (41%), Gaps = 39/501 (7%)

Query: 212  EDTKQQMTKMQE---NFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEIS 268
            E+ +QQ+  +Q+     I +E     EK +LL  IE  D     L++    + +A   I 
Sbjct: 874  ENLRQQLISLQQLKQQLILIE----QEKSQLLYKIEEFDRERQLLKQQ---ISSAN-NIK 925

Query: 269  LEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIE----EKGSLEIANMTEL 324
            +E   L +E E               + +Q +  +  +K E +    E   L ++     
Sbjct: 926  MESESLKREYEMLRMKLESSDREISTM-RQQLTLASNQKIEFDRLRSEYQQLRMSFEDSE 984

Query: 325  TKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKS 384
             +K  L + L   I   N+  + +        K   S  +K    I  +S ++  +  K 
Sbjct: 985  REKQGLKQQLQIGINVKNELEQFRKEYDLIRLKFEESEKEKNQLRIQYQSSQSNVNGYKI 1044

Query: 385  PWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISE---KDTXXXXXXXX 441
               QLSS+     + + + K EI  L   I    KD ++K+  I E   K          
Sbjct: 1045 QIEQLSSQINQFQSQELVMKREIEMLIQQIDVYKKDQINKQQQIQEYQFKYQEIMKEYEN 1104

Query: 442  XXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTE-DVNEIAKVQEQLKQELNDEIKDVNVKD 500
              GK   I    L ++ +     L       E +  EI + + Q+++ +   ++   ++ 
Sbjct: 1105 LQGKQKNIDVDALMYEIYELKKQLAQKDKQYEYERQEINEQKFQMEKSVKIRLEQ-EIRI 1163

Query: 501  LIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLK----LKQMQKTIDNFSKVSDSNKE 556
            L EK  S   ++ +L  +I    +  +K++S  ++K    + Q+Q+ I     V     E
Sbjct: 1164 LNEKFNS---ELNELRRQIQIEKQEKLKLESELRIKYEQQIMQLQQQIKPSVDVDALMYE 1220

Query: 557  IVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAI 616
            I  L ++     Q + ++++E+  L++ +    + + ++   ++  I M+   E R   I
Sbjct: 1221 IFELKKQAVTKEQVIEQMKKEQYQLRVQMEQRYNEQKLQ---FESEIRMKLERELR---I 1274

Query: 617  SLLESQKFDLVQELHILQQKYDEV--EDKLADISQLQSDQVCSEIKSVH--LEEQIDALS 672
            S+    ++ +  E +      D V   +K   + Q++ +++ + ++ +   L+E+++  +
Sbjct: 1275 SIESDLRYQIENEYNFESNIQDYVLQIEKWKSVCQMRDEEI-AHLRGLQQALKEKLNQYT 1333

Query: 673  ASKKELALVIENLKLDKEQLY 693
            +  + L   +  ++ D+  +Y
Sbjct: 1334 SEIESLRTQLALMQGDRRTVY 1354


>UniRef50_A0CJD5 Cluster: Chromosome undetermined scaffold_2, whole
            genome shotgun sequence; n=2; Paramecium tetraurelia|Rep:
            Chromosome undetermined scaffold_2, whole genome shotgun
            sequence - Paramecium tetraurelia
          Length = 986

 Score =  126 bits (304), Expect = 5e-27
 Identities = 172/862 (19%), Positives = 375/862 (43%), Gaps = 63/862 (7%)

Query: 451  QLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEE 510
            QLQL+++    G +   +    E++ + AK+ + L++++  +  D  +K+L E LK   +
Sbjct: 150  QLQLQNKL-FGGKAPEEISKELEELRKKAKILDDLQKKIGAKGPDELLKEL-ENLKKKAQ 207

Query: 511  QITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQK 570
            Q   +N +++  N       S+ + +L+++++  D F ++S        + +EL  L +K
Sbjct: 208  QFDDINKKLNGKNF------SDLEKELEKLRQKADKFDEISKQFSNPSDIQKELDQLKKK 261

Query: 571  VAELEEEKGNLQLHLVDYDSGRMIES-DVYKKMIEMENLAETRLK-AISLLESQKFDLVQ 628
             AEL++    L+  L + +  ++++S D  KK ++ ++     LK  +S L+  +     
Sbjct: 262  AAELDK----LKTQLNNQNPDQLLKSLDENKKQLQSKDREIGDLKRLLSELQQNQGSYDD 317

Query: 629  ELHILQQKYDEVEDKLADISQ-LQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKL 687
            ++ +LQQK DE+E+K+  ++Q L   ++  + K   L +       S+  LA +   L+ 
Sbjct: 318  QIRLLQQKIDELEEKVVGLAQELSRYKMLLKAKDDELNKLQLLFRDSETRLAQMNNELQR 377

Query: 688  DKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLT-DKLEKMSAEKISELLAKINHEEQSK 746
             K  L     DL+  + D+     +  +   DL+  + E  + ++ S+ L + N E    
Sbjct: 378  SKNDLQRAQGDLQRAQGDLQKAQGDLRKAQTDLSRSQQENQNLKQQSDDLRRQNQE---- 433

Query: 747  IQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYL 806
                       QE +   +++E++ ++   ++  +++ +  ++D +  L  K   L + L
Sbjct: 434  ---------LAQENNNLQQDLENQ-TQNLGQLDEIKDQLNELQDEKNQLNDKVSDLQNNL 483

Query: 807  QEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQ 866
            +EKQ+ + +   ++ EL + L  + D    +E +LLE++H    L+   Q   ++NQ L 
Sbjct: 484  KEKQRLFDQ---KQKELEDALKRVKD----LEAKLLEMDHYIDTLEDDLQKFEKDNQQLN 536

Query: 867  ISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIE 926
                  Q     L       D  +++  + Q +L  L++NL ++  + Q  + Q K E+ 
Sbjct: 537  REAGQKQLADRELERLRGLLDQMKNQYDQQQKELGKLKNNLDQM-RDLQDELAQAKSEL- 594

Query: 927  DLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNL 986
            D       Q +  +  K+    +  + ++ + +   QLQ+  NN++      + +   N 
Sbjct: 595  DRANSVIAQQQDELAQKENEISQLVREVQNLEESNNQLQDQNNNLQQTLQEQQAVTNGNQ 654

Query: 987  ELIDK--HVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVS 1044
            E + K   + +   +     E   NE + +   LKQ D  I  L           M+ + 
Sbjct: 655  EELTKLRRIAEDYKEKIRQLELKFNEYSNMEERLKQSDHRIAVL-----------MTEIE 703

Query: 1045 DYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFE- 1103
               S + Q T++ E+ +++  R+   LL+ +Q  +  +  V +    I E++  K   E 
Sbjct: 704  RLNSLVKQITSETEDWKQKHSRIELALLEYRQIEKTNRDAVNKNQQFINEIERLKKLLEA 763

Query: 1104 MNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQ------EEEEFIQERSVL 1157
             +I   + +     +E       N              + +Q      E E        +
Sbjct: 764  KHIELLQTIERCELLESQQQTLMNQVQDALKKADTGDEILLQYLLIAAENERLSGILQPM 823

Query: 1158 QEQSAKLNTELQECYTKIIQLE--TLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLS 1215
            QE+  +L T+++E   K  +L+  TL  +L  ++ + ++ I + ++K+  L+ E   L +
Sbjct: 824  QEKFNQLTTQVKEMTVKYTELQNKTLGIDLDEYERL-KKLIIEYENKIAMLSLEIQRLKA 882

Query: 1216 TVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSV 1275
                L  +  S        I   +   + Q   D      +L   ++   ++ + L  + 
Sbjct: 883  KTNILDKNGQSGNFGSNNNINIQYNSSMFQSNEDLSNKITDLLCLVAMMSAELDVLRSNN 942

Query: 1276 QSSTQEE-TNKIVTMEQVTSLQ 1296
            +   Q++  N+     +VT++Q
Sbjct: 943  EKQVQQQLVNQYRQNTEVTNIQ 964



 Score =  111 bits (267), Expect = 2e-22
 Identities = 193/888 (21%), Positives = 392/888 (44%), Gaps = 101/888 (11%)

Query: 474  DVNEIAKVQEQLKQELNDEIK--------DVNVKDLIEKLKSAEEQITQLNDEIDAANKN 525
            +V  + +   QLKQE+ + I         ++ ++DL+EKLK+   ++   ++E +     
Sbjct: 59   EVERLVRENTQLKQEIQNFIDSGLDRVNYEMQIRDLMEKLKNQTFEVNSYSEERERL-VI 117

Query: 526  MIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEI-VRLTEELH--HLSQKVA-ELEEEKGNL 581
            +I+   +   +L++  K  D   + S  + E+ ++L  +L      ++++ ELEE +   
Sbjct: 118  IIRELEDEIRRLEEQLKDYDPNWRKSQRDLELQLQLQNKLFGGKAPEEISKELEELRKKA 177

Query: 582  QLHLVDYDS--GRMIESDVYKKMIEMENLAETRLKAISLLESQKF-DLVQELHILQQK-- 636
            ++ L D     G     ++ K++  ++  A+        L  + F DL +EL  L+QK  
Sbjct: 178  KI-LDDLQKKIGAKGPDELLKELENLKKKAQQFDDINKKLNGKNFSDLEKELEKLRQKAD 236

Query: 637  -YDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGT 695
             +DE+  + ++ S +Q +    + K+  L++    L+    +  L  ++L  +K+QL   
Sbjct: 237  KFDEISKQFSNPSDIQKELDQLKKKAAELDKLKTQLNNQNPDQLL--KSLDENKKQLQSK 294

Query: 696  IKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDA 755
             +++ +     + +L + +Q+N    D   ++  +KI EL  K+            G+  
Sbjct: 295  DREIGD-----LKRLLSELQQNQGSYDDQIRLLQQKIDELEEKV-----------VGLAQ 338

Query: 756  KIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSE 815
            ++    + ++  + EL+K +      E  +A M +    L+R  + L     + Q+A  +
Sbjct: 339  ELSRYKMLLKAKDDELNKLQLLFRDSETRLAQMNNE---LQRSKNDLQRAQGDLQRAQGD 395

Query: 816  YTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQH 875
                + +L      L    +  E Q   ++ ++ +L+++NQ L +EN NLQ  L +  Q+
Sbjct: 396  LQKAQGDLRKAQTDLSRSQQ--ENQ--NLKQQSDDLRRQNQELAQENNNLQQDLENQTQN 451

Query: 876  YNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQ 935
               L E  ++ +  + E  +   ++ DL++NLK    E Q L  QK+KE+ED        
Sbjct: 452  LGQLDEIKDQLNELQDEKNQLNDKVSDLQNNLK----EKQRLFDQKQKELED-------- 499

Query: 936  IESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQK 995
               A++  K L  K  +   Y+  LE  LQ+++ + + LN    +    + EL  + ++ 
Sbjct: 500  ---ALKRVKDLEAKLLEMDHYIDTLEDDLQKFEKDNQQLNREAGQKQLADREL--ERLRG 554

Query: 996  QQTQSPDYTEQYINEINKL-NALLKQKD--EEIIALNQKINNAQVSYMSMVSDYESKLAQ 1052
               Q  +  +Q   E+ KL N L + +D  +E+     +++ A     S+++  + +LAQ
Sbjct: 555  LLDQMKNQYDQQQKELGKLKNNLDQMRDLQDELAQAKSELDRAN----SVIAQQQDELAQ 610

Query: 1053 FTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGM 1112
               ++  +  E+Q + +     +  N  LQ  ++EQ   +    + +LT    I +    
Sbjct: 611  KENEISQLVREVQNLEESNNQLQDQNNNLQQTLQEQ-QAVTNGNQEELTKLRRIAEDYKE 669

Query: 1113 IISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECY 1172
             I   +E   ++ +N++            L  + E        V Q  S   + + +   
Sbjct: 670  KIRQ-LELKFNEYSNMEERLKQSDHRIAVLMTEIER---LNSLVKQITSETEDWKQKHSR 725

Query: 1173 TKIIQLETLNTELTGHDVVNQEQ--INQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQ 1230
             ++  LE    E T  D VN+ Q  IN+++   + L  ++  LL T+             
Sbjct: 726  IELALLEYRQIEKTNRDAVNKNQQFINEIERLKKLLEAKHIELLQTIERC---------- 775

Query: 1231 RGFEIAELWKQHLAQREADFQK---TEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIV 1287
               E+ E  +Q L  +  D  K   T  E+ +Q     ++ E+ L  +    QE+ N++ 
Sbjct: 776  ---ELLESQQQTLMNQVQDALKKADTGDEILLQYLLIAAENER-LSGILQPMQEKFNQLT 831

Query: 1288 TM-----EQVTSLQNKLQ--DKEEHLRNLQEKYADVINQIEILRSEIE 1328
            T       + T LQNK    D +E+ R L++   +  N+I +L  EI+
Sbjct: 832  TQVKEMTVKYTELQNKTLGIDLDEYER-LKKLIIEYENKIAMLSLEIQ 878



 Score = 89.8 bits (213), Expect = 5e-16
 Identities = 193/999 (19%), Positives = 427/999 (42%), Gaps = 104/999 (10%)

Query: 575  EEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELH--- 631
            + ++ ++   L+  +  R++  +   K  E++N  ++ L  ++  E Q  DL+++L    
Sbjct: 45   QNQELDIACFLMAVEVERLVRENTQLKQ-EIQNFIDSGLDRVNY-EMQIRDLMEKLKNQT 102

Query: 632  ILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQ 691
                 Y E  ++L  I +   D++        LEEQ+     + ++    +E     + +
Sbjct: 103  FEVNSYSEERERLVIIIRELEDEIR------RLEEQLKDYDPNWRKSQRDLELQLQLQNK 156

Query: 692  LYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQF 751
            L+G         E+I  +L+   ++   L D  +K+ A+   ELL ++ + ++ K Q   
Sbjct: 157  LFGG-----KAPEEISKELEELRKKAKILDDLQKKIGAKGPDELLKELENLKK-KAQQFD 210

Query: 752  GIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQK 811
             I+ K+  ++    ++E EL K + +  + +E I+        ++++ DQL     E  K
Sbjct: 211  DINKKLNGKNF--SDLEKELEKLRQKADKFDE-ISKQFSNPSDIQKELDQLKKKAAELDK 267

Query: 812  AYSEYTIQE-DELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLS 870
              ++   Q  D+L+  L       +  ++++ +++    ELQ+      ++ + LQ  + 
Sbjct: 268  LKTQLNNQNPDQLLKSLDENKKQLQSKDREIGDLKRLLSELQQNQGSYDDQIRLLQQKID 327

Query: 871  DMQQHYNALVEKANRTDLA----ESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIE 926
            ++++    L ++ +R  +     + E  K Q   RD E+ L ++ +E Q      ++   
Sbjct: 328  ELEEKVVGLAQELSRYKMLLKAKDDELNKLQLLFRDSETRLAQMNNELQRSKNDLQRAQG 387

Query: 927  DLEIEFNTQIESAIRDKKV----LNEKYEKNIEYVTQ---LEAQLQEYKNNIENLNMNVE 979
            DL+      ++ A  D +     L+   ++N     Q   L  Q QE      NL  ++E
Sbjct: 388  DLQ-RAQGDLQKAQGDLRKAQTDLSRSQQENQNLKQQSDDLRRQNQELAQENNNLQQDLE 446

Query: 980  ELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSY 1039
               + NL  +D+ ++ Q  +  D   Q  ++++ L   LK+K        +++ +A    
Sbjct: 447  NQTQ-NLGQLDE-IKDQLNELQDEKNQLNDKVSDLQNNLKEKQRLFDQKQKELEDA---- 500

Query: 1040 MSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETK 1099
            +  V D E+KL +    ++ +E+++Q+  K      +   + Q+  RE +     L + K
Sbjct: 501  LKRVKDLEAKLLEMDHYIDTLEDDLQKFEKDNQQLNREAGQKQLADRELERLRGLLDQMK 560

Query: 1100 LTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVL-- 1157
              ++    K  G +  + ++ M D  + +                Q + E  +  SV+  
Sbjct: 561  NQYDQQ-QKELGKL-KNNLDQMRDLQDEL---------------AQAKSELDRANSVIAQ 603

Query: 1158 -QEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLST 1216
             Q++ A+   E+ +   ++  LE  N +L       Q+Q N L+  L++     +     
Sbjct: 604  QQDELAQKENEISQLVREVQNLEESNNQL-------QDQNNNLQQTLQEQQAVTNGNQEE 656

Query: 1217 VAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQ 1276
            + +LR  I+    ++  ++ EL     +  E   ++++H + V ++  E +   L+  + 
Sbjct: 657  LTKLRR-IAEDYKEKIRQL-ELKFNEYSNMEERLKQSDHRIAVLMTEIE-RLNSLVKQIT 713

Query: 1277 SSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXX 1336
            S T++   K   +E +  L+ +  +K    R+   K    IN+IE L+  +E + +    
Sbjct: 714  SETEDWKQKHSRIE-LALLEYRQIEKTN--RDAVNKNQQFINEIERLKKLLEAKHIELLQ 770

Query: 1337 XXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVN 1396
                              E     + Q+Q+++N   ++A  K  +              N
Sbjct: 771  TI----------------ERCELLESQQQTLMN-QVQDALKKADTGDEILLQYLLIAAEN 813

Query: 1397 DAEAKVLE-LTHQLELKDSEIYQKTHEYTI----TLTQRNDEFENVRQQLVEYEKRIEDL 1451
            +  + +L+ +  +     +++ + T +YT     TL    DE+E +++ ++EYE +I  L
Sbjct: 814  ERLSGILQPMQEKFNQLTTQVKEMTVKYTELQNKTLGIDLDEYERLKKLIIEYENKIAML 873

Query: 1452 TYEKESELAILRL--KMHENAN--HYETMQKESEIERVKLIEELNVKITESVSLNKQVAE 1507
            + E +   A   +  K  ++ N      +  +      +  E+L+ KIT+ + L   VA 
Sbjct: 874  SLEIQRLKAKTNILDKNGQSGNFGSNNNINIQYNSSMFQSNEDLSNKITDLLCL---VAM 930

Query: 1508 LNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNM 1546
            ++  L + +   NE Q  ++ Q +     N E+TN+Q +
Sbjct: 931  MSAEL-DVLRSNNEKQ--VQQQLVNQYRQNTEVTNIQTV 966



 Score = 89.8 bits (213), Expect = 5e-16
 Identities = 153/771 (19%), Positives = 337/771 (43%), Gaps = 76/771 (9%)

Query: 321  MTELTKKIELLEHLNCQIRQTNK-ELENKLATMGTESKAVSSPSKK--GSPLISRKSGRN 377
            + EL KK ++L+ L  +I      EL  +L  +  +++     +KK  G      +    
Sbjct: 170  LEELRKKAKILDDLQKKIGAKGPDELLKELENLKKKAQQFDDINKKLNGKNFSDLEKELE 229

Query: 378  TASKMKSPWSQLSSETLN-QDTDKKIN--KNEIAKLEMVIQSLNKDLVDKEYVISEKDTX 434
               +    + ++S +  N  D  K+++  K + A+L+ +   LN    D+     +++  
Sbjct: 230  KLRQKADKFDEISKQFSNPSDIQKELDQLKKKAAELDKLKTQLNNQNPDQLLKSLDENKK 289

Query: 435  XXXXXXXXXGK-DTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEI 493
                     G    L+++LQ     + +   L+    +  +   +   QE  + ++  + 
Sbjct: 290  QLQSKDREIGDLKRLLSELQQNQGSYDDQIRLLQQKIDELEEKVVGLAQELSRYKMLLKA 349

Query: 494  KDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSK---- 549
            KD  +  L    + +E ++ Q+N+E+  +  ++ + + + +     +QK   +  K    
Sbjct: 350  KDDELNKLQLLFRDSETRLAQMNNELQRSKNDLQRAQGDLQRAQGDLQKAQGDLRKAQTD 409

Query: 550  VSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLA 609
            +S S +E   L ++   L ++  EL +E  NLQ  L +         ++  ++ E+++  
Sbjct: 410  LSRSQQENQNLKQQSDDLRRQNQELAQENNNLQQDLENQTQNLGQLDEIKDQLNELQDEK 469

Query: 610  ETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQID 669
                  +S L++   +L ++  +  QK  E+ED L  +  L++  +  +     LE+ + 
Sbjct: 470  NQLNDKVSDLQN---NLKEKQRLFDQKQKELEDALKRVKDLEAKLLEMDHYIDTLEDDLQ 526

Query: 670  ALSASKKELALVIENLKL---DKEQLYGTIKDLEN---DKEDIMNKLQNYIQENMDLTDK 723
                  ++L       +L   + E+L G +  ++N    ++  + KL+N + +  DL D+
Sbjct: 527  KFEKDNQQLNREAGQKQLADRELERLRGLLDQMKNQYDQQQKELGKLKNNLDQMRDLQDE 586

Query: 724  LEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICR-LE 782
            L +  +E +    + I  ++    Q +  I   ++E    +E   ++L    + + + L+
Sbjct: 587  LAQAKSE-LDRANSVIAQQQDELAQKENEISQLVREVQ-NLEESNNQLQDQNNNLQQTLQ 644

Query: 783  ESIAVM---EDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELV---NRLAVLM----- 831
            E  AV    ++    L R A+     +++ +  ++EY+  E+ L    +R+AVLM     
Sbjct: 645  EQQAVTNGNQEELTKLRRIAEDYKEKIRQLELKFNEYSNMEERLKQSDHRIAVLMTEIER 704

Query: 832  -----------------DHDRVVEKQLLE---IEHENKELQKKNQILLEENQNLQISLSD 871
                              H R +E  LLE   IE  N++   KNQ  + E + L+  L  
Sbjct: 705  LNSLVKQITSETEDWKQKHSR-IELALLEYRQIEKTNRDAVNKNQQFINEIERLKKLL-- 761

Query: 872  MQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRI-THEH---QTLIVQKKKE--- 924
             +  +  L++   R +L ES+    QT +  ++  LK+  T +    Q L++  + E   
Sbjct: 762  -EAKHIELLQTIERCELLESQQ---QTLMNQVQDALKKADTGDEILLQYLLIAAENERLS 817

Query: 925  --IEDLEIEFN---TQI-ESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNV 978
              ++ ++ +FN   TQ+ E  ++  ++ N+    +++   +L+  + EY+N I  L++ +
Sbjct: 818  GILQPMQEKFNQLTTQVKEMTVKYTELQNKTLGIDLDEYERLKKLIIEYENKIAMLSLEI 877

Query: 979  EELNKMNLELIDKHVQKQQTQSPDYTE-QYINEINKLNALLKQKDEEIIAL 1028
            + L K    ++DK+ Q     S +    QY + + + N  L  K  +++ L
Sbjct: 878  QRL-KAKTNILDKNGQSGNFGSNNNINIQYNSSMFQSNEDLSNKITDLLCL 927



 Score = 43.6 bits (98), Expect = 0.046
 Identities = 100/527 (18%), Positives = 203/527 (38%), Gaps = 33/527 (6%)

Query: 140 QLGD-VTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXX 198
           QL D V+ L N +KEK       Q +++     + DL+ K+ E D  I+     T     
Sbjct: 471 QLNDKVSDLQNNLKEKQRLFDQKQKELEDALKRVKDLEAKLLEMDHYID-----TLEDDL 525

Query: 199 XXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANK 258
                           KQ   +  E    +  + K++  +  K++      +  + +   
Sbjct: 526 QKFEKDNQQLNREAGQKQLADRELERLRGLLDQMKNQYDQQQKELGKLKNNLDQMRDLQD 585

Query: 259 LLEAARFEISLEHSKLAQ---ELEQXXXXXXXXXXXXXXLAK---QSIEPSCEEKTEIEE 312
            L  A+ E+   +S +AQ   EL Q              L +   Q  + +   +  ++E
Sbjct: 586 ELAQAKSELDRANSVIAQQQDELAQKENEISQLVREVQNLEESNNQLQDQNNNLQQTLQE 645

Query: 313 KGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISR 372
           + ++   N  ELTK   + E    +IRQ    LE K        + +     + + L++ 
Sbjct: 646 QQAVTNGNQEELTKLRRIAEDYKEKIRQ----LELKFNEYSNMEERLKQSDHRIAVLMTE 701

Query: 373 KSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLE-MVIQSLNKDLVDK-EYVISE 430
               N+  K      Q++SET  +D  +K ++ E+A LE   I+  N+D V+K +  I+E
Sbjct: 702 IERLNSLVK------QITSET--EDWKQKHSRIELALLEYRQIEKTNRDAVNKNQQFINE 753

Query: 431 KDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELN 490
            +                I + +L   Q     + +       D  +   +Q  L    N
Sbjct: 754 IERLKKLLEAKHIELLQTIERCELLESQQQTLMNQVQDALKKADTGDEILLQYLLIAAEN 813

Query: 491 DEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKV 550
           + +  + ++ + EK      Q+ ++  +        + +  +   +LK++   I+  +K+
Sbjct: 814 ERLSGI-LQPMQEKFNQLTTQVKEMTVKYTELQNKTLGIDLDEYERLKKL--IIEYENKI 870

Query: 551 SDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAE 610
           +  + EI RL  + + L  K  +      N  +++    S      D+  K+ ++  L  
Sbjct: 871 AMLSLEIQRLKAKTNIL-DKNGQSGNFGSNNNINIQYNSSMFQSNEDLSNKITDLLCLVA 929

Query: 611 TRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCS 657
                + +L S     VQ+  + Q + +    ++ +I  +QS +  S
Sbjct: 930 MMSAELDVLRSNNEKQVQQQLVNQYRQN---TEVTNIQTVQSVETTS 973


>UniRef50_O61308 Cluster: 227 kDa spindle- and centromere-associated
            protein; n=1; Parascaris univalens|Rep: 227 kDa spindle-
            and centromere-associated protein - Parascaris univalens
          Length = 1955

 Score =  126 bits (304), Expect = 5e-27
 Identities = 253/1333 (18%), Positives = 563/1333 (42%), Gaps = 116/1333 (8%)

Query: 212  EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271
            EDTK  + K  EN         +E   L    E+    I+ LE   K +   R EIS E 
Sbjct: 570  EDTKLDLLKDLENQRTRYDAVTNELDTLQTTFETSTKNIAQLEANIKEINLMRDEISKEK 629

Query: 272  SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELL 331
              LAQ+L                + ++ I+ SC   +E  EK  L+I    E  +++  L
Sbjct: 630  DSLAQKL-----ADVTHKLEIETVRREDIQRSCVGHSEDVEKQRLQI---IEYEREVMAL 681

Query: 332  EHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPL---ISRKSGRNTASKMKSPWS- 387
              LN ++    K  + K+ ++     +V +   K + L   + ++     +SK K+    
Sbjct: 682  RRLNDELDTNVKTGQAKVTSLENSIISVQTEVTKLTTLNDKLQKEKQSIMSSKQKADTDV 741

Query: 388  QLSSE---TLNQDTDKKINKNE-IAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXX 443
             L  E    L Q+ DK   +N+ + + E + + + K+   + +++ E+D           
Sbjct: 742  DLLKEKLRKLEQECDKLKEENKALHEDEQIARQMCKEEASRIHLL-ERDLKDAMTEVEEL 800

Query: 444  GKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIE 503
             K   + ++  E+ + +E      + ++T D +EIA            E  +V VK+L E
Sbjct: 801  KKQ--LQKMDEENSERLESVLRTKISSDTVDTSEIA------------EYTEVKVKELRE 846

Query: 504  KLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEE 563
            K K+  E++    D+++     +++ +   + ++ + Q+T  N  K+ +   E  RL  E
Sbjct: 847  KYKADLERLQSNKDDLE-RRVQILEDELAERQRIVERQRTEMNDLKL-EYQLESDRLRAE 904

Query: 564  LHHLSQKV-AELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQ 622
            +  +  K  +E+E+E+        D DS ++   ++  K+  ME + E         E++
Sbjct: 905  MATVELKYQSEVEDERDQRSR---DADSWKVTSEELRSKISFMEKMLE---------EAK 952

Query: 623  KFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVI 682
              + V     L+++  E E+K  DI   +S ++ +EI+ +  + + D +   KK++ +  
Sbjct: 953  HRETV-----LREEATEWEEK-HDIISNESLKLRNEIERIRSDAEED-IQKWKKDVHMAQ 1005

Query: 683  ENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSA--EKISELLAKIN 740
              LK + E++  T++       D +  L   I E    T K+ ++++   ++ E LA  +
Sbjct: 1006 NELK-NLERVCETLRSQLTAANDRVASLNTTINEQ---TSKIRELNSHEHRLEEDLAD-S 1060

Query: 741  HEEQSKIQTQFG-IDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKA 799
                S I+   G    +++  + +   ++SE  K K+ I  L+  I  + + + S E + 
Sbjct: 1061 RATSSAIENDLGNATGRLRSSEEHNAILQSENRKSKTEIEALKHQIDTIMNTKESCESEV 1120

Query: 800  DQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDH-DRVVEKQLLEIEHENKELQKKNQIL 858
            ++    L++K    +  T +++E + +L +  DH +R   ++  E++   KE++K  +  
Sbjct: 1121 ER----LKKKIVQTTTITKEQNEKIEKLRIEHDHLERDYREKTKEVD-RLKEVEKTFE-- 1173

Query: 859  LEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHE-HQTL 917
            L+ N+  Q    ++ +    L+      +    E+ K   +++ ++  L+  + E H+ L
Sbjct: 1174 LKVNRARQ----ELDEFSKKLIVTETERNAISGEAQKLDKEVQLVKEQLQYKSDEFHKAL 1229

Query: 918  --IVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLN 975
              +    +  E+  +    Q+E+   +   L  + E + + +  L+   QEY N  +   
Sbjct: 1230 DELANAHRISEEGRVNAIHQLEARRFEIDDLKSRLENSEQRLATLQ---QEYVNADKERG 1286

Query: 976  MNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNA 1035
               + + +    +    V ++         Q    ++++ A+ ++++E   +LN+  N  
Sbjct: 1287 ALNDAMRRFQATISRSVVAEEHVDVSTIETQMQKLMSRIEAIERERNEYRDSLNRLKNRC 1346

Query: 1036 QVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKEL 1095
              SY S V   E+    F  ++ + E+E ++V  +L   K+  +  +  ++++D++ + L
Sbjct: 1347 STSY-SSVDRQETVYRTFEERVISAEDERRKVELKLSSMKEMLKSQEEKLKQRDEERRNL 1405

Query: 1096 KETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERS 1155
            K   +TFE+     E     + I  ++D    V             L+ + +E++   R 
Sbjct: 1406 KSNIVTFEL-----EARAKDAQIRHLNDLLKRVQAELENSQNDNRALR-ERQEQYETNRI 1459

Query: 1156 VLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLS 1215
             L++   +L T+  E   K + +    TE         + + +L S+L+   T+N +L  
Sbjct: 1460 HLEQ---RLPTDEGEPRVKAL-MAAFATERQS----LSDSLKKLASQLQISETKNADLRD 1511

Query: 1216 TVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSV 1275
                L+  +  A       + E  +++L + + +  +   +LR QL   +S      D  
Sbjct: 1512 DAERLKRDLLKAE-----RVEEDLRRNLVE-QTEIMRENQQLRSQLGVAQS------DLA 1559

Query: 1276 QSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIE---ILRSEIEDEKV 1332
             +S +++  +     ++ +++ +L+D ++HL +   + A++  Q++     +S + D  +
Sbjct: 1560 NASGRKQQLE----GELAAVRAELRDHKQHLHDAISRIAELQRQLQDANAEKSRLTDRII 1615

Query: 1333 AFXXXXXXXXXXXXXXXXDLRTENQSYKQM-QEQSILNINEENAQLKKSSXXXXXXXXXX 1391
                               L T     K +  E   +       + +K            
Sbjct: 1616 GLEKTIGTLRNTETELRAQLSTAADERKALNSELEEMRRRIVQMESEKKDVDNQLEEVNK 1675

Query: 1392 XXRVNDAEAKVLEL-THQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIED 1450
               +   + ++LE   H  EL  SE   +      +L     E + + +   + +++I  
Sbjct: 1676 ARIIMTKKIEILETEKHSAELVISETASQREAIERSLNALERENKELYKNCAQLQQQIAQ 1735

Query: 1451 LTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELN-VKITESVSLNKQVAELN 1509
            L  +    L  L  K  E+   +    K  +++  +++E  +  + +    L  Q++ + 
Sbjct: 1736 LEMDNGERLIALTTKQKEDHEKFVAAVKAEKVQVERIVENRDRAQKSRIRQLENQLSMMR 1795

Query: 1510 KALEEEVAKTNEM 1522
            + L+ E A++++M
Sbjct: 1796 EQLDNERARSHQM 1808



 Score = 98.7 bits (235), Expect = 1e-18
 Identities = 206/1170 (17%), Positives = 478/1170 (40%), Gaps = 110/1170 (9%)

Query: 495  DVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSN 554
            D  ++ +  KLK+++ Q+ +L   ++   +   + +S+ +L   + +  I   + V D+N
Sbjct: 393  DSEMQHIQRKLKNSDTQVCELTTRLEGTEE--ARRRSDKQLVDAKREINIQQRA-VDDAN 449

Query: 555  KEIVRLTEELHHL-SQKVA------ELEEE--KGNLQLHLVDYDSGRMI--ESDVYKKMI 603
            +E+ R+ + LH + S+K+       +LEEE  +  LQ+     D  R +  E ++ K+++
Sbjct: 450  RELRRVEDRLHIMESEKIVAENARQQLEEEVRRLTLQVDQSKADGERRVVEEGEIQKRIV 509

Query: 604  EME--NLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKL-ADISQLQSDQVC-SEI 659
            E E  ++     + ++  + +   L  +L   +++   VE +  + + +L+   +    +
Sbjct: 510  EDEYRSMISELTRRMNAFQDENKRLKNDLGCTKERLKNVEFEYNSTVRKLEDKDIALKHL 569

Query: 660  KSVHLE---------EQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKL 710
            +   L+          + DA++     L    E    +  QL   IK++   +++I  + 
Sbjct: 570  EDTKLDLLKDLENQRTRYDAVTNELDTLQTTFETSTKNIAQLEANIKEINLMRDEISKEK 629

Query: 711  QNYIQENMDLTDKLEKMSAEKISELLAKINH-EEQSKIQTQF---------------GID 754
             +  Q+  D+T KLE  +  +     + + H E+  K + Q                 +D
Sbjct: 630  DSLAQKLADVTHKLEIETVRREDIQRSCVGHSEDVEKQRLQIIEYEREVMALRRLNDELD 689

Query: 755  AKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSL---ERKADQLGSYLQEKQK 811
              ++     + ++E+ +   ++ + +L      ++  + S+   ++KAD     L+EK +
Sbjct: 690  TNVKTGQAKVTSLENSIISVQTEVTKLTTLNDKLQKEKQSIMSSKQKADTDVDLLKEKLR 749

Query: 812  AYSE---------YTIQEDELVNRLAVLMDHDRV--VEKQLLEIEHENKELQKKNQILLE 860
               +           + EDE + R     +  R+  +E+ L +   E +EL+K+ Q + E
Sbjct: 750  KLEQECDKLKEENKALHEDEQIARQMCKEEASRIHLLERDLKDAMTEVEELKKQLQKMDE 809

Query: 861  EN-QNLQISL-SDMQQHYNALVEKANRTDLAESE-STKYQTQLRDLESNLKRITHEHQTL 917
            EN + L+  L + +        E A  T++   E   KY+  L  L+SN   +    Q L
Sbjct: 810  ENSERLESVLRTKISSDTVDTSEIAEYTEVKVKELREKYKADLERLQSNKDDLERRVQIL 869

Query: 918  ---IVQKKKEIEDLEIEFN-TQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIEN 973
               + ++++ +E    E N  ++E  +   ++  E     ++Y +++E +  +   + ++
Sbjct: 870  EDELAERQRIVERQRTEMNDLKLEYQLESDRLRAEMATVELKYQSEVEDERDQRSRDADS 929

Query: 974  LNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKIN 1033
              +  EEL +  +  ++K +++ + +     E+      K + +      E + L  +I 
Sbjct: 930  WKVTSEEL-RSKISFMEKMLEEAKHRETVLREEATEWEEKHDII----SNESLKLRNEIE 984

Query: 1034 NAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIK 1093
              +      +  ++  +     +L+N+E   + +  QL  +      L   + EQ  +I+
Sbjct: 985  RIRSDAEEDIQKWKKDVHMAQNELKNLERVCETLRSQLTAANDRVASLNTTINEQTSKIR 1044

Query: 1094 ELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQE 1153
            EL   +   E ++   +    SS IE   +D  N              L+ +  +   + 
Sbjct: 1045 ELNSHEHRLEEDL--ADSRATSSAIE---NDLGNATGRLRSSEEHNAILQSENRKSKTEI 1099

Query: 1154 RSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLK---SKLEQLNTEN 1210
             ++  +    +NT+ + C +++ +L+    + T       E+I +L+     LE+   E 
Sbjct: 1100 EALKHQIDTIMNTK-ESCESEVERLKKKIVQTTTITKEQNEKIEKLRIEHDHLERDYREK 1158

Query: 1211 DNLLSTVAELRSSISSAVDQRGFEIAELWKQHL------------AQR-EADFQKTEHEL 1257
               +  + E+  +    V++   E+ E  K+ +            AQ+ + + Q  + +L
Sbjct: 1159 TKEVDRLKEVEKTFELKVNRARQELDEFSKKLIVTETERNAISGEAQKLDKEVQLVKEQL 1218

Query: 1258 RVQLSAFESKYEQLLDSVQSSTQEETNKIVTME----QVTSLQNKLQDKEEHLRNLQEKY 1313
            + +   F    ++L ++ + S +   N I  +E    ++  L+++L++ E+ L  LQ++Y
Sbjct: 1219 QYKSDEFHKALDELANAHRISEEGRVNAIHQLEARRFEIDDLKSRLENSEQRLATLQQEY 1278

Query: 1314 ADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEE 1373
             +   +   L   +   +                       +  S  +  E+      + 
Sbjct: 1279 VNADKERGALNDAMRRFQATISRSVVAEEHVDVSTIETQMQKLMSRIEAIERERNEYRDS 1338

Query: 1374 NAQLKKSSXXXXXXXXXXXXRVNDAEAKVL---ELTHQLELKDSEIYQKTHEYTITLTQR 1430
              +LK                    E +V+   +   ++ELK S + +        L QR
Sbjct: 1339 LNRLKNRCSTSYSSVDRQETVYRTFEERVISAEDERRKVELKLSSMKEMLKSQEEKLKQR 1398

Query: 1431 NDEFENVRQQLV--EYEKRIEDLTYEKESEL---AILRLKMHENANH-YETMQKESEIER 1484
            ++E  N++  +V  E E R +D      ++L       L+  +N N      Q++ E  R
Sbjct: 1399 DEERRNLKSNIVTFELEARAKDAQIRHLNDLLKRVQAELENSQNDNRALRERQEQYETNR 1458

Query: 1485 VKLIEELNVKITES--VSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITN 1542
            + L + L     E    +L    A   ++L + + K   + + L+  E +   L D+   
Sbjct: 1459 IHLEQRLPTDEGEPRVKALMAAFATERQSLSDSLKK---LASQLQISETKNADLRDDAER 1515

Query: 1543 L-QNMVRASSSKIQKHVSFASDTKQGRDEQ 1571
            L +++++A   +     +    T+  R+ Q
Sbjct: 1516 LKRDLLKAERVEEDLRRNLVEQTEIMRENQ 1545



 Score = 86.2 bits (204), Expect = 7e-15
 Identities = 199/987 (20%), Positives = 403/987 (40%), Gaps = 106/987 (10%)

Query: 633  LQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIE-NLKLDKEQ 691
            LQ+K +E   ++ D  +  S Q  ++  S  ++E  D      K  A   E   +LD+E+
Sbjct: 102  LQRKIEEYRRRIVDAEKQVSIQKANDDVSFSIKETADTWLPDMKSDAADYEWASRLDEER 161

Query: 692  LYGTIKDLENDKEDI-MNKLQNYIQENMDLTDKLEKMSAEKISELLAKINH------EEQ 744
                   ++  ++ + + +LQ Y + NM   +K+ +   + ++  L           EE 
Sbjct: 162  RRNDELHMQITQQQVDLQRLQKYFEANMQEKEKIYQTREKNLAYYLNAEQRKMLDLWEEL 221

Query: 745  SKIQTQFGIDAKIQERDLYIENIESELSKYKSRI--------------CRLEESIAVMED 790
             +++ QF    +  ERDL  EN ++E++K    +                L + + ++E 
Sbjct: 222  QRVRRQFADYKEQTERDL--ENQKNEVAKVTQSVGGMAGRLNTSSHGDSGLVQDVVLLEA 279

Query: 791  RRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKE 850
             R   E +A  +G+   +      +Y    +E V R+  L  H      ++L +E    E
Sbjct: 280  MRRFRELQAVPVGASADDYNALMKKY----EETVERVIELESHGDGSTAKMLSLE---AE 332

Query: 851  LQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRI 910
            L++     +E ++ L+  L D+        E+ ++            +++     N+ R 
Sbjct: 333  LRRTKDKFIECSEFLR-KLGDLAAGSYRGDERTSKIVSLSPGGMSLPSEIYRSVRNILR- 390

Query: 911  THEHQTLIVQKKKEIEDLEI-EFNTQIESAIR-----DKKVLNEKYEKNIEY--VTQLEA 962
             H+ +   +Q+K +  D ++ E  T++E         DK++++ K E NI+   V     
Sbjct: 391  NHDSEMQHIQRKLKNSDTQVCELTTRLEGTEEARRRSDKQLVDAKREINIQQRAVDDANR 450

Query: 963  QLQEYKNNIENLNMN--VEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQ 1020
            +L+  ++ +  +     V E  +  LE   + +  Q  QS    E+ + E  ++   + +
Sbjct: 451  ELRRVEDRLHIMESEKIVAENARQQLEEEVRRLTLQVDQSKADGERRVVEEGEIQKRIVE 510

Query: 1021 KDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSK---QH 1077
              +E  ++  ++     ++       ++ L     +L+N+E E     ++L D     +H
Sbjct: 511  --DEYRSMISELTRRMNAFQDENKRLKNDLGCTKERLKNVEFEYNSTVRKLEDKDIALKH 568

Query: 1078 NEELQI-LVREQDDQ-------IKELKETKLTFEM---NIPKTEGMIISSTIEPMSDD-A 1125
             E+ ++ L+++ ++Q         EL   + TFE    NI + E  I    I  M D+ +
Sbjct: 569  LEDTKLDLLKDLENQRTRYDAVTNELDTLQTTFETSTKNIAQLEANI--KEINLMRDEIS 626

Query: 1126 NNVDXXXXXXXXXXXXLKVQE-EEEFIQERSV-LQEQSAKLNTELQECYTKIIQLETLNT 1183
               D            L+++    E IQ   V   E   K   ++ E   +++ L  LN 
Sbjct: 627  KEKDSLAQKLADVTHKLEIETVRREDIQRSCVGHSEDVEKQRLQIIEYEREVMALRRLND 686

Query: 1184 ELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVD--QRGFEIAELWKQ 1241
            EL  +    Q ++  L++ +  + TE   L +   +L+    S +   Q+     +L K+
Sbjct: 687  ELDTNVKTGQAKVTSLENSIISVQTEVTKLTTLNDKLQKEKQSIMSSKQKADTDVDLLKE 746

Query: 1242 HLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQD 1301
             L + E +  K + E +        + EQ+    +   +EE ++I  +E+   L++ + +
Sbjct: 747  KLRKLEQECDKLKEENKAL-----HEDEQI---ARQMCKEEASRIHLLER--DLKDAMTE 796

Query: 1302 KEEHLRNLQEKYADVINQIE-ILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYK 1360
             EE  + LQ+   +   ++E +LR++I  + V                  +LR   + YK
Sbjct: 797  VEELKKQLQKMDEENSERLESVLRTKISSDTV----DTSEIAEYTEVKVKELR---EKYK 849

Query: 1361 QMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKT 1420
               E+  L  N+++ + +                    E   L+L +QLE         T
Sbjct: 850  ADLER--LQSNKDDLERRVQILEDELAERQRIVERQRTEMNDLKLEYQLESDRLRAEMAT 907

Query: 1421 HEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKES 1480
             E      +   E E+ R Q        +  + E  S+++ +  KM E A H ET+ +E 
Sbjct: 908  VEL-----KYQSEVEDERDQRSRDADSWKVTSEELRSKISFME-KMLEEAKHRETVLRE- 960

Query: 1481 EIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNE----MQTALENQEIEIVTL 1536
              E  +  E+ ++   ES+ L  ++  +    EE++ K  +     Q  L+N E    TL
Sbjct: 961  --EATEWEEKHDIISNESLKLRNEIERIRSDAEEDIQKWKKDVHMAQNELKNLERVCETL 1018

Query: 1537 -------NDEITNLQNMVRASSSKIQK 1556
                   ND + +L   +   +SKI++
Sbjct: 1019 RSQLTAANDRVASLNTTINEQTSKIRE 1045



 Score = 72.1 bits (169), Expect = 1e-10
 Identities = 160/879 (18%), Positives = 353/879 (40%), Gaps = 80/879 (9%)

Query: 695  TIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKI-NHEEQSKIQ-TQFG 752
            ++  L+ D      ++    +E  +  D +  +   KI E   +I + E+Q  IQ     
Sbjct: 70   SVSGLDRDLNSFKKRIDANTEEQREHADMMVGLQ-RKIEEYRRRIVDAEKQVSIQKANDD 128

Query: 753  IDAKIQER-DLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQK 811
            +   I+E  D ++ +++S+ + Y+    RL+E       R   L  +  Q    LQ  QK
Sbjct: 129  VSFSIKETADTWLPDMKSDAADYEWA-SRLDEE----RRRNDELHMQITQQQVDLQRLQK 183

Query: 812  AYSEYTIQEDELV--NRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQ-NLQIS 868
             Y E  +QE E +   R   L  +    ++++L++  E + ++++     E+ + +L+  
Sbjct: 184  -YFEANMQEKEKIYQTREKNLAYYLNAEQRKMLDLWEELQRVRRQFADYKEQTERDLENQ 242

Query: 869  LSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDL 928
             +++ +   ++   A R + +    +     +  LE+ ++R        +     +   L
Sbjct: 243  KNEVAKVTQSVGGMAGRLNTSSHGDSGLVQDVVLLEA-MRRFRELQAVPVGASADDYNAL 301

Query: 929  EIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLEL 988
              ++   +E  I     L    + +   +  LEA+L+  K+     +  + +L  +    
Sbjct: 302  MKKYEETVERVIE----LESHGDGSTAKMLSLEAELRRTKDKFIECSEFLRKLGDLAAGS 357

Query: 989  I--DKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDY 1046
               D+   K  + SP            +  +L+  D E+  + +K+ N+           
Sbjct: 358  YRGDERTSKIVSLSPGGMSLPSEIYRSVRNILRNHDSEMQHIQRKLKNS----------- 406

Query: 1047 ESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNI 1106
            ++++ + TT+LE  EE  +R  KQL+D+K+   E+ I  R  DD  +EL+  ++   ++I
Sbjct: 407  DTQVCELTTRLEGTEEARRRSDKQLVDAKR---EINIQQRAVDDANRELR--RVEDRLHI 461

Query: 1107 PKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNT 1166
             ++E ++  +  + + ++   +               V+E E  IQ+R V  E       
Sbjct: 462  MESEKIVAENARQQLEEEVRRLTLQVDQSKADGERRVVEEGE--IQKRIVEDE------- 512

Query: 1167 ELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISS 1226
                 Y  +I      +ELT      Q++  +LK+    L    + L +   E  S++  
Sbjct: 513  -----YRSMI------SELTRRMNAFQDENKRLKN---DLGCTKERLKNVEFEYNSTV-- 556

Query: 1227 AVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKI 1286
                R  E  ++  +HL   + D  K     R +  A  ++ + L  + ++ST+      
Sbjct: 557  ----RKLEDKDIALKHLEDTKLDLLKDLENQRTRYDAVTNELDTLQTTFETSTKNIAQLE 612

Query: 1287 VTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXX 1346
              ++++  +++++  +++   +L +K ADV +++EI     ED + +             
Sbjct: 613  ANIKEINLMRDEISKEKD---SLAQKLADVTHKLEIETVRREDIQRS-CVGHSEDVEKQR 668

Query: 1347 XXXXDLRTENQSYKQMQEQSILNINEENAQLK--KSSXXXXXXXXXXXXRVNDAEAKVLE 1404
                +   E  + +++ ++   N+    A++   ++S             +ND   K  +
Sbjct: 669  LQIIEYEREVMALRRLNDELDTNVKTGQAKVTSLENSIISVQTEVTKLTTLNDKLQKEKQ 728

Query: 1405 LTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRL 1464
                 + K         E    L Q  D+ +   + L E E+    +  E+ S + +L  
Sbjct: 729  SIMSSKQKADTDVDLLKEKLRKLEQECDKLKEENKALHEDEQIARQMCKEEASRIHLLER 788

Query: 1465 KMHENANHYE----TMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEV---- 1516
             + +     E     +QK  E    +L   L  KI+       ++AE  +   +E+    
Sbjct: 789  DLKDAMTEVEELKKQLQKMDEENSERLESVLRTKISSDTVDTSEIAEYTEVKVKELREKY 848

Query: 1517 -AKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKI 1554
             A    +Q+  ++ E  +  L DE+   Q +V    +++
Sbjct: 849  KADLERLQSNKDDLERRVQILEDELAERQRIVERQRTEM 887


>UniRef50_Q8IWJ2 Cluster: GRIP and coiled-coil domain-containing
            protein 2; n=25; Euteleostomi|Rep: GRIP and coiled-coil
            domain-containing protein 2 - Homo sapiens (Human)
          Length = 1583

 Score =  126 bits (304), Expect = 5e-27
 Identities = 243/1171 (20%), Positives = 499/1171 (42%), Gaps = 127/1171 (10%)

Query: 473  EDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSA-EEQITQLNDEIDAAN-------- 523
            E +N   ++ EQLK + N E     +++ IEK++   EEQI  L  ++DA          
Sbjct: 57   EAMNTQLELSEQLKFQNNSEDNVKKLQEEIEKIRPGFEEQILYLQKQLDATTDEKKETVT 116

Query: 524  --KNMIKVKSNHKLK-LKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGN 580
              +N+I+  S H  K +  +Q+ +     +    +E+  L  ++   S K  E E  K N
Sbjct: 117  QLQNIIEANSQHYQKNINSLQEELLQLKAIHQ--EEVKELMCQIE-ASAKEHEAEINKLN 173

Query: 581  -LQLHLVDYDSGRMIESDVYKKM-IEMENLAETRLKA-----ISLLESQKFDLVQELHIL 633
             L+ +LV        E ++ KK   E+ENL +    A     I  +  Q+   V++  ++
Sbjct: 174  ELKENLVKQCEAS--EKNIQKKYECELENLRKATSNANQDNQICSILLQENTFVEQ--VV 229

Query: 634  QQKYDEVEDKLADISQLQS---DQVCSEIKSVHLEEQIDALSAS------KKELALVIEN 684
             +K   +ED L ++    S   D+V + + ++ L+ ++DA          +++L   I  
Sbjct: 230  NEKVKHLEDTLKELESQHSILKDEV-TYMNNLKLKLEMDAQHIKDEFFHEREDLEFKINE 288

Query: 685  LKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAK-INHEE 743
            L L KE+    I+ L+++   +  +    ++++      L++   ++ISEL    ++  E
Sbjct: 289  LLLAKEEQGCVIEKLKSELAGLNKQFCYTVEQHNREVQSLKEQHQKEISELNETFLSDSE 348

Query: 744  QSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLG 803
            + K+   F I   ++E+    EN++ E  +    I   E    +ME  +  L   A   G
Sbjct: 349  KEKLTLMFEIQG-LKEQ---CENLQQEKQE---AILNYESLREIMEILQTELGESA---G 398

Query: 804  SYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQ 863
               QE +    +      EL  +L         + + +  ++ EN++L  + +++ E   
Sbjct: 399  KISQEFESMKQQQASDVHELQQKLRTAFTEKDALLETVNRLQGENEKLLSQQELVPE--- 455

Query: 864  NLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKK 923
             L+ ++ ++Q+     +   ++ D          T L++LE  +  +T E    I + K 
Sbjct: 456  -LENTIKNLQEKNGVYLLSLSQRD----------TMLKELEGKINSLTEEKDDFINKLKN 504

Query: 924  EIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENL----NMNVE 979
              E+++  F+ + E   R    L +K E+ I+Y ++LE ++ E    +E      + N +
Sbjct: 505  SHEEMD-NFHKKCEREERLILELGKKVEQTIQYNSELEQKVNELTGGLEETLKEKDQNDQ 563

Query: 980  ELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEI-IALNQKINNAQVS 1038
            +L K+ +++  K + + +       +    E NKL++  KQ   ++ + L+QK     V 
Sbjct: 564  KLEKLMVQM--KVLSEDKEVLSAEVKSLYEENNKLSSEKKQLSRDLEVFLSQK---EDVI 618

Query: 1039 YMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKET 1098
                ++  E KL     + +N+ + ++    Q L  K    +L   ++E   ++ E  E 
Sbjct: 619  LKEHITQLEKKLQLMVEEQDNLNKLLENEQVQKLFVKT---QLYGFLKEMGSEVSEDSEE 675

Query: 1099 KLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQ 1158
            K    +N+ +  G  ++   E   + A   D            L++++E + +QE SV+Q
Sbjct: 676  KDV--VNVLQAVGESLAKINEEKCNLAFQRDEKV---------LELEKEIKCLQEESVVQ 724

Query: 1159 EQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVA 1218
             +  +L + L++   + + L     E+       Q  + ++K+  E+   EN NLL  V 
Sbjct: 725  CE--ELKSLLRDYEQEKVLLRKELEEIQSEKEALQSDLLEMKNANEKTRLENQNLLIQVE 782

Query: 1219 ELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSS 1278
            E+  + S +      E   + K+H   +    QK   + R +L   +    +   SV++ 
Sbjct: 783  EVSQTCSKSEIHNEKEKCFI-KEHENLKPLLEQKELRDRRAELILLKDSLAKS-PSVKND 840

Query: 1279 TQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXX 1338
                  ++   E++ +L+ + ++KEE +  ++        +++  R E +  K       
Sbjct: 841  PLSSVKELE--EKIENLEKECKEKEEKINKIKLVAVKAKKELDSSRKETQTVKEELESLR 898

Query: 1339 XXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDA 1398
                        DL    +SYK +    +L   +++ QL                R N+ 
Sbjct: 899  SEKDQLSASMR-DLIQGAESYKNL----LLEYEKQSEQLDVEKE-----------RANNF 942

Query: 1399 EAKVLELTHQLE---LKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEK 1455
            E ++ +LT QL    L+   I     +    +       + +  Q++E ++    +  E 
Sbjct: 943  EHRIEDLTRQLRNSTLQCETINSDNEDLLARIETLQSNAKLLEVQILEVQRAKAMVDKEL 1002

Query: 1456 ESELAILRLKMHENA---NHYETMQKESEIERVKL---IEELNV---KITESVSLNKQVA 1506
            E+E      K+ E+A   N  E +Q + + ++ +L   ++EL +      ++  +N ++A
Sbjct: 1003 EAEKLQKEQKIKEHATTVNELEELQVQLQKQKKQLQKTMQELELVKKDAQQTTLMNMEIA 1062

Query: 1507 ELNKALEEEVAKTNEMQTALEN--QEIEIV-----TLNDEITNLQNMVRASSSKIQKHVS 1559
            +  + ++E   K       +E+  QEI+I      TL +EIT+LQ+ V+    K  K   
Sbjct: 1063 DYERLMKELNQKLTNKNNKIEDLEQEIKIQKQKQETLQEEITSLQSSVQQYEEKNTKIKQ 1122

Query: 1560 FASDTKQGRDEQLDNTMNKELLDAVPRAELD 1590
                TK+   +      +  +L A  + EL+
Sbjct: 1123 LLVKTKKELADSKQAETDHLILQASLKGELE 1153



 Score = 98.3 bits (234), Expect = 2e-18
 Identities = 191/963 (19%), Positives = 380/963 (39%), Gaps = 81/963 (8%)

Query: 144  VTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKIN----EKDQII-EAKNKATTXXXX 198
            V  L NTIK       V  + +   +T + +L+ KIN    EKD  I + KN        
Sbjct: 453  VPELENTIKNLQEKNGVYLLSLSQRDTMLKELEGKINSLTEEKDDFINKLKNSHEEMDNF 512

Query: 199  XXXXXXXXXXXXXEDTKQQMTKMQENFIAMEA-EWKDEKQRLLKDIESKDVRISSLEEAN 257
                            K + T    + +  +  E     +  LK+ +  D ++  L    
Sbjct: 513  HKKCEREERLILELGKKVEQTIQYNSELEQKVNELTGGLEETLKEKDQNDQKLEKLMVQM 572

Query: 258  KLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEK-TEIEEKGSL 316
            K+L   +  +S E   L +E  +                 Q  +   +E  T++E+K  L
Sbjct: 573  KVLSEDKEVLSAEVKSLYEENNKLSSEKKQLSRDLEVFLSQKEDVILKEHITQLEKKLQL 632

Query: 317  EIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPL-ISRKSG 375
             +     L K   LLE+   Q      +L   L  MG+E   VS  S++   + + +  G
Sbjct: 633  MVEEQDNLNK---LLENEQVQKLFVKTQLYGFLKEMGSE---VSEDSEEKDVVNVLQAVG 686

Query: 376  RNTASKMKSPWS---QLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKD 432
             + A   +   +   Q   + L  + + K  + E       ++SL +D  ++E V+  K+
Sbjct: 687  ESLAKINEEKCNLAFQRDEKVLELEKEIKCLQEESVVQCEELKSLLRD-YEQEKVLLRKE 745

Query: 433  TXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDE 492
                         D L+       +  +E  +L+      E+V++     E   ++    
Sbjct: 746  LEEIQSEKEALQSD-LLEMKNANEKTRLENQNLL---IQVEEVSQTCSKSEIHNEKEKCF 801

Query: 493  IKD-VNVKDLIE--KLKSAEEQITQLNDEI----DAANKNMIKVK------SNHKLKLKQ 539
            IK+  N+K L+E  +L+    ++  L D +       N  +  VK       N + + K+
Sbjct: 802  IKEHENLKPLLEQKELRDRRAELILLKDSLAKSPSVKNDPLSSVKELEEKIENLEKECKE 861

Query: 540  MQKTIDNFSKVS-DSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDV 598
             ++ I+    V+  + KE+    +E   + +++  L  EK  L   + D   G     ++
Sbjct: 862  KEEKINKIKLVAVKAKKELDSSRKETQTVKEELESLRSEKDQLSASMRDLIQGAESYKNL 921

Query: 599  YKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEV----EDKLADISQLQSDQ 654
              +  +     +   +  +  E +  DL ++L     + + +    ED LA I  LQS+ 
Sbjct: 922  LLEYEKQSEQLDVEKERANNFEHRIEDLTRQLRNSTLQCETINSDNEDLLARIETLQSNA 981

Query: 655  VCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYI 714
               E++ + ++    A +   KEL    E  KL KEQ         N+ E++  +LQ   
Sbjct: 982  KLLEVQILEVQR---AKAMVDKEL----EAEKLQKEQKIKEHATTVNELEELQVQLQKQK 1034

Query: 715  QENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKY 774
            ++      +LE +  +     L  +   +  ++  +  ++ K+  ++  IE++E E+   
Sbjct: 1035 KQLQKTMQELELVKKDAQQTTLMNMEIADYERLMKE--LNQKLTNKNNKIEDLEQEIKIQ 1092

Query: 775  KSR-------ICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRL 827
            K +       I  L+ S+   E++   +++   +    L + ++A +++ I +  L   L
Sbjct: 1093 KQKQETLQEEITSLQSSVQQYEEKNTKIKQLLVKTKKELADSKQAETDHLILQASLKGEL 1152

Query: 828  AVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTD 887
                    V + QL EI  E  ++ +  +   E++Q    +LS  QQ   AL E+     
Sbjct: 1153 EASQQQVEVYKIQLAEITSEKHKIHEHLKTSAEQHQR---TLSAYQQRVTALQEECR--- 1206

Query: 888  LAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQ----IESAIRDK 943
             A++E     T   + ES   R+   H  L  QK K +   E E   Q    +E  I   
Sbjct: 1207 AAKAEQA---TVTSEFESYKVRV---HNVLKQQKNKSMSQAETEGAKQEREHLEMLIDQL 1260

Query: 944  KVLNEKYEKNIEY-VTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDK--HVQKQQTQS 1000
            K+  +  + N++  V++L+    E+   +E  N  ++E      EL +K   +Q +    
Sbjct: 1261 KIKLQDSQNNLQINVSELQTLQSEHDTLLERHNKMLQETVSKEAELREKLCSIQSENMMM 1320

Query: 1001 PDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENM 1060
                 Q ++++   N +L+       +   ++ + Q  +   V   + +L++   +L  +
Sbjct: 1321 KSEHTQTVSQLTSQNEVLRN------SFRDQVRHLQEEHRKTVETLQQQLSKMEAQLFQL 1374

Query: 1061 EEE 1063
            + E
Sbjct: 1375 KNE 1377



 Score = 80.2 bits (189), Expect = 4e-13
 Identities = 141/689 (20%), Positives = 293/689 (42%), Gaps = 85/689 (12%)

Query: 907  LKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQE 966
            +K+   +  T +    KE+E   I +  +IE+   +   +  KY    E    L+ QL+E
Sbjct: 1    MKQEVEDSVTKMGDAHKELEQSHINYVKEIENLKNELMAVRSKYS---EDKANLQKQLEE 57

Query: 967  YKNNIENLNMNVEELNKM--NLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEE 1024
              N    L+  ++  N    N++ + + ++K +   P + EQ +    +L+A   +K E 
Sbjct: 58   AMNTQLELSEQLKFQNNSEDNVKKLQEEIEKIR---PGFEEQILYLQKQLDATTDEKKET 114

Query: 1025 IIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQIL 1084
            +  L   I      Y   ++  + +L Q   K  + EE  + + +    +K+H  E+  L
Sbjct: 115  VTQLQNIIEANSQHYQKNINSLQEELLQL--KAIHQEEVKELMCQIEASAKEHEAEINKL 172

Query: 1085 VREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKV 1144
               +++ +K+ + +    E NI K     + + +   + +AN  +              +
Sbjct: 173  NELKENLVKQCEAS----EKNIQKKYECELEN-LRKATSNANQDNQICSI---------L 218

Query: 1145 QEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLE 1204
             +E  F+++  V+ E+   L   L+E  +   Q   L  E+T         +N LK KLE
Sbjct: 219  LQENTFVEQ--VVNEKVKHLEDTLKELES---QHSILKDEVT--------YMNNLKLKLE 265

Query: 1205 -QLNTENDNLLSTVAELRSSISS---AVDQRGFEIAELWKQHLAQREADFQKTEHELRVQ 1260
                   D       +L   I+    A +++G  I +L K  LA     F  T  +   +
Sbjct: 266  MDAQHIKDEFFHEREDLEFKINELLLAKEEQGCVIEKL-KSELAGLNKQFCYTVEQHNRE 324

Query: 1261 LSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQI 1320
            + + + ++++ +  +  +   ++ K    E++T L  ++Q  +E   NLQ++  + I   
Sbjct: 325  VQSLKEQHQKEISELNETFLSDSEK----EKLT-LMFEIQGLKEQCENLQQEKQEAILNY 379

Query: 1321 EILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKS 1380
            E LR  +E  +                        +Q ++ M++Q   +++E   +L ++
Sbjct: 380  ESLREIMEILQTELGESAGKI--------------SQEFESMKQQQASDVHELQQKL-RT 424

Query: 1381 SXXXXXXXXXXXXRVNDAEAKVL---ELTHQLELKDSEIYQKTHEYTITLTQRNDEFENV 1437
            +            R+     K+L   EL  +LE     + +K   Y ++L+QR+      
Sbjct: 425  AFTEKDALLETVNRLQGENEKLLSQQELVPELENTIKNLQEKNGVYLLSLSQRD------ 478

Query: 1438 RQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITE 1497
               L E E +I  LT EK+  +  L+    E  N ++  ++E      +LI EL  K+ +
Sbjct: 479  -TMLKELEGKINSLTEEKDDFINKLKNSHEEMDNFHKKCEREE-----RLILELGKKVEQ 532

Query: 1498 SVSLN----KQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSK 1553
            ++  N    ++V EL   LEE + + ++    LE   +++  L+++   L   V+   S 
Sbjct: 533  TIQYNSELEQKVNELTGGLEETLKEKDQNDQKLEKLMVQMKVLSEDKEVLSAEVK---SL 589

Query: 1554 IQKHVSFASDTKQ-GRDEQLDNTMNKELL 1581
             +++   +S+ KQ  RD ++  +  ++++
Sbjct: 590  YEENNKLSSEKKQLSRDLEVFLSQKEDVI 618



 Score = 76.6 bits (180), Expect = 5e-12
 Identities = 152/707 (21%), Positives = 290/707 (41%), Gaps = 72/707 (10%)

Query: 837  VEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKY 896
            VE  + ++   +KEL++ +   ++E +NL+  L  ++  Y+   +KAN   L +      
Sbjct: 5    VEDSVTKMGDAHKELEQSHINYVKEIENLKNELMAVRSKYSE--DKAN---LQKQLEEAM 59

Query: 897  QTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEY 956
             TQL +L   LK   +  +  + + ++EIE +   F  QI   +  +K L+   ++  E 
Sbjct: 60   NTQL-ELSEQLK-FQNNSEDNVKKLQEEIEKIRPGFEEQI---LYLQKQLDATTDEKKET 114

Query: 957  VTQL----EAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEIN 1012
            VTQL    EA  Q Y+ NI +L   + +L  ++ E     V++   Q     +++  EIN
Sbjct: 115  VTQLQNIIEANSQHYQKNINSLQEELLQLKAIHQE----EVKELMCQIEASAKEHEAEIN 170

Query: 1013 KLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLL 1072
            KLN L +            +   + S  ++   YE +L        N  ++ Q  S  L 
Sbjct: 171  KLNELKE----------NLVKQCEASEKNIQKKYECELENLRKATSNANQDNQICSILLQ 220

Query: 1073 DSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXX 1132
            ++    + +   V+  +D +KEL+      +  +     + +   ++             
Sbjct: 221  ENTFVEQVVNEKVKHLEDTLKELESQHSILKDEVTYMNNLKLKLEMDAQHIKDEFFHERE 280

Query: 1133 XXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVN 1192
                     L  +EE+  + E+  L+ + A LN   Q CYT    +E  N E+      +
Sbjct: 281  DLEFKINELLLAKEEQGCVIEK--LKSELAGLNK--QFCYT----VEQHNREVQSLKEQH 332

Query: 1193 QEQINQL-KSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQ 1251
            Q++I++L ++ L     E   L+  +  L+    +   ++  + A L  + L +     Q
Sbjct: 333  QKEISELNETFLSDSEKEKLTLMFEIQGLKEQCENLQQEK--QEAILNYESLREIMEILQ 390

Query: 1252 KTEHELRVQLS-AFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQ 1310
                E   ++S  FES  +Q    V    Q+        + +    N+LQ + E L + Q
Sbjct: 391  TELGESAGKISQEFESMKQQQASDVHELQQKLRTAFTEKDALLETVNRLQGENEKLLSQQ 450

Query: 1311 EKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNI 1370
            E   ++ N I+ L+ +                         L   +   K++ E  I ++
Sbjct: 451  ELVPELENTIKNLQEK------------------NGVYLLSLSQRDTMLKEL-EGKINSL 491

Query: 1371 NEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELK---DSEIYQKTHEYTITL 1427
             EE                    +    E  +LEL  ++E     +SE+ QK +E T  L
Sbjct: 492  TEEKDDFINKLKNSHEEMDNFHKKCEREERLILELGKKVEQTIQYNSELEQKVNELTGGL 551

Query: 1428 TQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKL 1487
             +   E +   Q+L +   +++ L+ +KE   A       E  + YE   K S  E+ +L
Sbjct: 552  EETLKEKDQNDQKLEKLMVQMKVLSEDKEVLSA-------EVKSLYEENNKLSS-EKKQL 603

Query: 1488 IEELNVKIT--ESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIE 1532
              +L V ++  E V L + + +L K L+  V + + +   LEN++++
Sbjct: 604  SRDLEVFLSQKEDVILKEHITQLEKKLQLMVEEQDNLNKLLENEQVQ 650


>UniRef50_Q245H6 Cluster: Putative uncharacterized protein; n=1;
            Tetrahymena thermophila SB210|Rep: Putative
            uncharacterized protein - Tetrahymena thermophila SB210
          Length = 1610

 Score =  126 bits (303), Expect = 7e-27
 Identities = 188/911 (20%), Positives = 378/911 (41%), Gaps = 83/911 (9%)

Query: 449  IAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSA 508
            IA LQ E +Q +E   +      T++V  + K+Q++    L ++I + N K L + L+ +
Sbjct: 324  IADLQAEMKQILEKLQM-----QTDEVERLKKLQQETIDTLQNKI-EFNEKSLRDNLEES 377

Query: 509  EEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVR--LTEELHH 566
            +  I     +I   N+ + ++       +    K +   +K +D+ ++ ++  L    + 
Sbjct: 378  QRIIANQQVDIQYKNRQIAELSQKLTQSITDHAKQLQLLAKEADAQRDDIQQELIANSNA 437

Query: 567  LSQKVAELEEEKGNLQL-HLVDYDSGRMIESDVYKK---MIEMENLAETRLKAISLLESQ 622
            L   + +L+ +   +Q  + V +D  + +  D + K   + E+E   +     I+ L+ +
Sbjct: 438  LENDIQDLKSQLTRIQNENTVLHDENKKLFYDSHSKENRIKELEGQIKQNQSKINDLQQK 497

Query: 623  KFDLVQELHILQQKYDEVE--------DKLADISQLQSD----QVCSEIKSVH--LEEQI 668
              DL +  + L ++   ++        D  A I+Q +      Q   +++++H  L+E++
Sbjct: 498  LEDLNKLSNHLDEQNRSLDAQNQQFFNDNKALIAQTEEQEKAIQNLKDLETLHIQLQEKL 557

Query: 669  DALSASKKELALV----IENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKL 724
              + + K  LA      IE  +  K QL+   +  E +K   ++      +  + L  ++
Sbjct: 558  KLIESEKASLAQTAQQHIEESEKYKNQLFELQQGQEKEKRYALDGQMRLKENEVSLKIEV 617

Query: 725  EKMSAE-KISELL--AKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRL 781
            E+  +E K ++LL   K++ +++     Q  +++   E+   +E +     KY+ +    
Sbjct: 618  ERQQSEIKHNQLLFEEKLSTKQKEIEFIQIQLNSTTSEKVKCLETLSELTKKYEQQ---- 673

Query: 782  EESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQL 841
            +E +  +++++  LE K + L + LQEK  A+ + +IQ D L      + +      +Q+
Sbjct: 674  KEKLKDLQEQKIQLEAKINNLEALLQEKNNAFEKTSIQIDLLTQESQTIKEQYNQKVRQI 733

Query: 842  LEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAE--SESTKYQTQ 899
              ++ EN     K      +NQ L   L D+ Q  N  VEK    DL +  SE  + Q Q
Sbjct: 734  -SLQEENISQYAK------DNQKLNNELKDLLQEKNN-VEKKLLLDLQQKTSEVAQLQQQ 785

Query: 900  LRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQ 959
            ++  +  L+    +H   + ++K  +E     F  + +   ++     E+ E+ IE +T+
Sbjct: 786  IKATQKQLQFEAQQHNLQVEREKLYMEQQLKTFEQKCQELQQNLIQKEEEQEEFIEQLTE 845

Query: 960  LEAQLQEYKNNIENLNMNVEE----LNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLN 1015
             E  L E +N IE L +  ++    LN   L+L D   QK++       +Q     +KL 
Sbjct: 846  KETMLNEQRNQIEELKLQFQKEEDSLNSEILQLQDSLKQKEKQYHIYQKQQKEYTQDKLK 905

Query: 1016 ALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSK 1075
             +L    E      Q +   Q    S ++D  S+  Q+   +     E +   K   D++
Sbjct: 906  GVLSSLAEA----RQDLTIFQSKCNSEINDTHSRTLQYFQDIMQFSREQKSKLKVQYDNE 961

Query: 1076 QHNEELQILVREQDDQIKE---LKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXX 1132
                +  I  + +    KE   ++E +  F   I   E  ++        ++        
Sbjct: 962  MEKYQENISTKFETQLDKERLIMRERESHFNKQISLLEQKVLEQNTR-FQEEKQKYQQEI 1020

Query: 1133 XXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVN 1192
                      K+Q   E IQ ++ L +  ++    +++      QLE +N       V+ 
Sbjct: 1021 NSLEERNITEKIQLNNEIIQLKNQLLKVESRSARSVEKNQK---QLEMVNQNAQKSQVMY 1077

Query: 1193 QEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQK 1252
               I+ +K+KLE+   +    L  + E RS I +             K HL Q E +   
Sbjct: 1078 ANMISDIKNKLEESEKKE---LQVLNETRSKIHN------------MKAHLQQIELEDSN 1122

Query: 1253 TEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNK--LQDKEEHLRNLQ 1310
             +       ++  +K     D   S+    TN I     + SLQN   LQ +      LQ
Sbjct: 1123 EQLAHSTSSTSSMNKQNSNNDGRSSNNLNNTNNI----NIDSLQNNTLLQTQRTARLALQ 1178

Query: 1311 EKYADVINQIE 1321
            ++Y   +   +
Sbjct: 1179 KEYEKTMKNFQ 1189



 Score =  123 bits (297), Expect = 4e-26
 Identities = 213/1074 (19%), Positives = 475/1074 (44%), Gaps = 101/1074 (9%)

Query: 509  EEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLS 568
            +E IT L++   ++     ++K   + +L Q ++ +   SK++  N+      E+L   +
Sbjct: 60   DELITTLSESQTSSEFIEERIKEIIENQLFQEKEQV--ISKLASDNQAFQLKIEQLEIDN 117

Query: 569  QKVAELEEEKGNLQLHLVDYDSGRMIES--DVYKKMIEMENLAETRLKAISLLESQKFDL 626
            Q +A   +   N Q++ ++Y+  ++ ++  ++ +K   +E L +   +    L+ +K +L
Sbjct: 118  QTLASSIQSVHN-QVNNLNYEGDKLKKNTLELNEKDARIEQLLDKITRQEGQLQ-EKENL 175

Query: 627  VQELHILQQKYD---EVE-DKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVI 682
            +Q+  I +Q+ +   + E +KL  + QLQ  +   E++  +L+++ D L +   +L    
Sbjct: 176  IQQKDIDKQRVELQLQTERNKLTHVDQLQGVE---EVEKKNLQQKYDELLSKYDKLNEEF 232

Query: 683  ENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHE 742
              ++L  EQ+ G   +  N++E     +     +  D T  L K+  ++  ++      E
Sbjct: 233  NGIRLRYEQI-GV--ERINEQEQYKLLIDQIKVKCKDKTHNL-KIKYKQYKDMSRNFQ-E 287

Query: 743  EQSKIQTQFGI-DAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQ 801
            +  + +T+F   + ++ E  + ++     + +Y+ +I  L+   A M+     L+ + D+
Sbjct: 288  KLIQNETEFSNKNLQVNEMKIKVQESSRAIIEYQRQIADLQ---AEMKQILEKLQMQTDE 344

Query: 802  LGSYLQEKQKAYSEYTIQEDELVNRLAVLMD--HDRVVEKQLLEIEHENKELQKKNQILL 859
            +     E+ K   + TI  D L N++        D + E Q + I ++  ++Q KN+ + 
Sbjct: 345  V-----ERLKKLQQETI--DTLQNKIEFNEKSLRDNLEESQRI-IANQQVDIQYKNRQIA 396

Query: 860  EENQNLQISLSDMQQHYNALVEKAN--RTDLAE---SESTKYQTQLRDLESNLKRITHEH 914
            E +Q L  S++D  +    L ++A+  R D+ +   + S   +  ++DL+S L RI +E+
Sbjct: 397  ELSQKLTQSITDHAKQLQLLAKEADAQRDDIQQELIANSNALENDIQDLKSQLTRIQNEN 456

Query: 915  QTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENL 974
              L  + KK   D   + N                       + +LE Q+++ ++ I +L
Sbjct: 457  TVLHDENKKLFYDSHSKENR----------------------IKELEGQIKQNQSKINDL 494

Query: 975  NMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINN 1034
               +E+LNK++      H+ +Q        +Q+ N+   L A  +++++ I  L   +  
Sbjct: 495  QQKLEDLNKLS-----NHLDEQNRSLDAQNQQFFNDNKALIAQTEEQEKAIQNLKD-LET 548

Query: 1035 AQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKE 1094
              +     +   ES+ A      +   EE ++   QL + +Q  E+ +      D Q++ 
Sbjct: 549  LHIQLQEKLKLIESEKASLAQTAQQHIEESEKYKNQLFELQQGQEKEKRYAL--DGQMR- 605

Query: 1095 LKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQ-E 1153
            LKE +++ ++ + + +  I  + +  + ++  +                 Q+E EFIQ +
Sbjct: 606  LKENEVSLKIEVERQQSEIKHNQL--LFEEKLSTK---------------QKEIEFIQIQ 648

Query: 1154 RSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNT--END 1211
             +    +  K    L E   K  Q +    +L    +  + +IN L++ L++ N   E  
Sbjct: 649  LNSTTSEKVKCLETLSELTKKYEQQKEKLKDLQEQKIQLEAKINNLEALLQEKNNAFEKT 708

Query: 1212 NL-LSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQ 1270
            ++ +  + +   +I    +Q+  +I+ L +++++Q   D QK  +EL+  L    +  ++
Sbjct: 709  SIQIDLLTQESQTIKEQYNQKVRQIS-LQEENISQYAKDNQKLNNELKDLLQEKNNVEKK 767

Query: 1271 LLDSVQSSTQEETNKIVTMEQVTSLQNKLQ-DKEEHLRNLQEKYADVINQIEILRSEIED 1329
            LL  +Q  T E        +Q+ + Q +LQ + ++H   ++ +   +  Q++    + ++
Sbjct: 768  LLLDLQQKTSEVAQ---LQQQIKATQKQLQFEAQQHNLQVEREKLYMEQQLKTFEQKCQE 824

Query: 1330 EKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXX 1389
             +                        N+   Q++E   L   +E   L            
Sbjct: 825  LQQNLIQKEEEQEEFIEQLTEKETMLNEQRNQIEELK-LQFQKEEDSLNSEILQLQDSLK 883

Query: 1390 XXXXRVNDAEAKVLELTHQLELKD--SEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKR 1447
                + +  + +  E T Q +LK   S + +   + TI  ++ N E  +   + ++Y + 
Sbjct: 884  QKEKQYHIYQKQQKEYT-QDKLKGVLSSLAEARQDLTIFQSKCNSEINDTHSRTLQYFQD 942

Query: 1448 IEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLI-EELNVKITESVSLNKQ-V 1505
            I   + E++S+L +      E      + + E+++++ +LI  E      + +SL +Q V
Sbjct: 943  IMQFSREQKSKLKVQYDNEMEKYQENISTKFETQLDKERLIMRERESHFNKQISLLEQKV 1002

Query: 1506 AELNKALEEEVAKTNEMQTALENQEI-EIVTLNDEITNLQNMVRASSSKIQKHV 1558
             E N   +EE  K  +   +LE + I E + LN+EI  L+N +    S+  + V
Sbjct: 1003 LEQNTRFQEEKQKYQQEINSLEERNITEKIQLNNEIIQLKNQLLKVESRSARSV 1056



 Score =  105 bits (252), Expect = 1e-20
 Identities = 174/912 (19%), Positives = 398/912 (43%), Gaps = 82/912 (8%)

Query: 458  QHMEGPSLIHVGTNTEDVNEIAKVQ---EQLKQELNDEIKDVNVKDLIEKLKSAEEQITQ 514
            +   G  L +     E +NE  + +   +Q+K +  D+  ++ +K    K  S   Q   
Sbjct: 230  EEFNGIRLRYEQIGVERINEQEQYKLLIDQIKVKCKDKTHNLKIKYKQYKDMSRNFQEKL 289

Query: 515  LNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSK-VSDSNKEIVRLTEELHHLSQKVAE 573
            + +E + +NKN+    +  K+K+++  + I  + + ++D   E+ ++ E+L   + +V  
Sbjct: 290  IQNETEFSNKNL--QVNEMKIKVQESSRAIIEYQRQIADLQAEMKQILEKLQMQTDEVER 347

Query: 574  LEEEKGNLQLHLVDYDSGRM--IESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELH 631
            L++    LQ   +D    ++   E  +   + E + +   +   I     Q  +L Q+L 
Sbjct: 348  LKK----LQQETIDTLQNKIEFNEKSLRDNLEESQRIIANQQVDIQYKNRQIAELSQKLT 403

Query: 632  ILQQKYDEVEDKLADISQLQSDQVCSEI--KSVHLEEQIDALSASKKELALVIENLKLDK 689
                 + +    LA  +  Q D +  E+   S  LE  I  L +    +      L  + 
Sbjct: 404  QSITDHAKQLQLLAKEADAQRDDIQQELIANSNALENDIQDLKSQLTRIQNENTVLHDEN 463

Query: 690  EQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMS--AEKISELLAKINHEEQSKI 747
            ++L+      EN  +++  +++    +  DL  KLE ++  +  + E    ++ + Q   
Sbjct: 464  KKLFYDSHSKENRIKELEGQIKQNQSKINDLQQKLEDLNKLSNHLDEQNRSLDAQNQQFF 523

Query: 748  QTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQ 807
                 + A+ +E++  I+N    L   ++   +L+E + ++E  + SL + A Q   +++
Sbjct: 524  NDNKALIAQTEEQEKAIQN----LKDLETLHIQLQEKLKLIESEKASLAQTAQQ---HIE 576

Query: 808  EKQKAYSE-YTIQEDELVNRLAVLMDHDRVVEKQL---LEIEHENKELQKKNQILLEENQ 863
            E +K  ++ + +Q+ +   +   L    R+ E ++   +E+E +  E+ K NQ+L EE  
Sbjct: 577  ESEKYKNQLFELQQGQEKEKRYALDGQMRLKENEVSLKIEVERQQSEI-KHNQLLFEE-- 633

Query: 864  NLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKK 923
                 LS  Q+    +  + N T    SE  K       LE+ L  +T +++    Q+K+
Sbjct: 634  ----KLSTKQKEIEFIQIQLNST---TSEKVKC------LET-LSELTKKYE----QQKE 675

Query: 924  EIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVT-QLEAQLQEYKNNIENLNMNVEE-- 980
            +++DL+ E   Q+E+ I + + L ++     E  + Q++   QE +   E  N  V +  
Sbjct: 676  KLKDLQ-EQKIQLEAKINNLEALLQEKNNAFEKTSIQIDLLTQESQTIKEQYNQKVRQIS 734

Query: 981  LNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYM 1040
            L + N+    K  QK   +  D  ++  N   KL   L+QK  E+  L Q+I   Q    
Sbjct: 735  LQEENISQYAKDNQKLNNELKDLLQEKNNVEKKLLLDLQQKTSEVAQLQQQIKATQKQLQ 794

Query: 1041 SMVSDY----ESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEEL-------QILVREQD 1089
                 +    E +      +L+  E++ Q + + L+  ++  EE        + ++ EQ 
Sbjct: 795  FEAQQHNLQVEREKLYMEQQLKTFEQKCQELQQNLIQKEEEQEEFIEQLTEKETMLNEQR 854

Query: 1090 DQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEE 1149
            +QI+ELK  +   E +   +E + +  +++      +                 +    E
Sbjct: 855  NQIEELK-LQFQKEEDSLNSEILQLQDSLKQKEKQYHIYQKQQKEYTQDKLKGVLSSLAE 913

Query: 1150 FIQERSVLQEQSAKLNTELQECYTKIIQL--ETLNTELTGHDVVNQEQINQLKSKLEQLN 1207
              Q+ ++ Q   +K N+E+ + +++ +Q   + +         +  +  N+++   E ++
Sbjct: 914  ARQDLTIFQ---SKCNSEINDTHSRTLQYFQDIMQFSREQKSKLKVQYDNEMEKYQENIS 970

Query: 1208 TENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESK 1267
            T+ +  L     +     S  +++      L +Q + ++   FQ+ + + + ++++ E +
Sbjct: 971  TKFETQLDKERLIMRERESHFNKQ----ISLLEQKVLEQNTRFQEEKQKYQQEINSLEER 1026

Query: 1268 YEQLLDSVQSSTQ--EETNKIVTME-----QVTSLQNKLQDKEEHLRNLQEKYADVINQI 1320
               + + +Q + +  +  N+++ +E      V   Q +L+   ++ +  Q  YA++I+ I
Sbjct: 1027 --NITEKIQLNNEIIQLKNQLLKVESRSARSVEKNQKQLEMVNQNAQKSQVMYANMISDI 1084

Query: 1321 EILRSEIEDEKV 1332
            +    E E +++
Sbjct: 1085 KNKLEESEKKEL 1096



 Score =  103 bits (247), Expect = 4e-20
 Identities = 185/911 (20%), Positives = 372/911 (40%), Gaps = 61/911 (6%)

Query: 719  DLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSR- 777
            DL    E+  + ++S L  KI ++E     ++    ++  E  +  E IE++L + K + 
Sbjct: 37   DLYSFYEQRLSAQMSLLYQKIINDELITTLSESQTSSEFIEERIK-EIIENQLFQEKEQV 95

Query: 778  ICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVV 837
            I +L       + +   LE     L S +Q      +    + D+L      L + D  +
Sbjct: 96   ISKLASDNQAFQLKIEQLEIDNQTLASSIQSVHNQVNNLNYEGDKLKKNTLELNEKDARI 155

Query: 838  EKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQ 897
            E+ L +I  +  +LQ+K  ++ +++ + Q     +Q   N L        + E E    Q
Sbjct: 156  EQLLDKITRQEGQLQEKENLIQQKDIDKQRVELQLQTERNKLTHVDQLQGVEEVEKKNLQ 215

Query: 898  TQLRDLESNLKRITHE-------HQTLIVQKKKEIEDLEIEFNTQIESAIRDK-KVLNEK 949
             +  +L S   ++  E       ++ + V++  E E  ++  + QI+   +DK   L  K
Sbjct: 216  QKYDELLSKYDKLNEEFNGIRLRYEQIGVERINEQEQYKLLID-QIKVKCKDKTHNLKIK 274

Query: 950  YEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYIN 1009
            Y++  +     + +L + +    N N+ V E+ K+ ++   + + + Q Q  D   +   
Sbjct: 275  YKQYKDMSRNFQEKLIQNETEFSNKNLQVNEM-KIKVQESSRAIIEYQRQIADLQAEMKQ 333

Query: 1010 EINKL-------NALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEE 1062
             + KL         L K + E I  L  KI   + S    + + +  +A     ++    
Sbjct: 334  ILEKLQMQTDEVERLKKLQQETIDTLQNKIEFNEKSLRDNLEESQRIIANQQVDIQYKNR 393

Query: 1063 EMQRVSKQLLDS-KQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPM 1121
            ++  +S++L  S   H ++LQ+L +E D Q  ++++ +L    N  + +   + S +  +
Sbjct: 394  QIAELSQKLTQSITDHAKQLQLLAKEADAQRDDIQQ-ELIANSNALENDIQDLKSQLTRI 452

Query: 1122 SDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETL 1181
             ++ N V              K    +E   E  + Q QS K+N +LQ+      +LE L
Sbjct: 453  QNE-NTVLHDENKKLFYDSHSKENRIKEL--EGQIKQNQS-KIN-DLQQ------KLEDL 501

Query: 1182 NTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQ 1241
            N +L+ H     EQ   L ++ +Q   +N  L++   E   +I +  D     I    K 
Sbjct: 502  N-KLSNH---LDEQNRSLDAQNQQFFNDNKALIAQTEEQEKAIQNLKDLETLHIQLQEKL 557

Query: 1242 HLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQD 1301
             L + E        +  ++ S    KY+  L  +Q   QE+  +     Q+   +N++  
Sbjct: 558  KLIESEKASLAQTAQQHIEES---EKYKNQLFELQQG-QEKEKRYALDGQMRLKENEVSL 613

Query: 1302 KEEHLRNLQE-KYADVI--NQIEILRSEIEDEKVAFXXXXXXX---XXXXXXXXXDLRTE 1355
            K E  R   E K+  ++   ++   + EIE  ++                         +
Sbjct: 614  KIEVERQQSEIKHNQLLFEEKLSTKQKEIEFIQIQLNSTTSEKVKCLETLSELTKKYEQQ 673

Query: 1356 NQSYKQMQEQSI---LNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELK 1412
             +  K +QEQ I     IN   A L++ +               +++  + E  +Q   +
Sbjct: 674  KEKLKDLQEQKIQLEAKINNLEALLQEKNNAFEKTSIQIDLLTQESQT-IKEQYNQKVRQ 732

Query: 1413 DSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAIL--RLKMHENA 1470
             S   +   +Y     + N+E +++ Q+    EK++     +K SE+A L  ++K  +  
Sbjct: 733  ISLQEENISQYAKDNQKLNNELKDLLQEKNNVEKKLLLDLQQKTSEVAQLQQQIKATQKQ 792

Query: 1471 NHYETMQKESEIERVKLIEELNVKITES--VSLNKQVAELNKALEEEVAKTNEMQTALEN 1528
              +E  Q   ++ER KL  E  +K  E     L + + +  +  EE + +  E +T L  
Sbjct: 793  LQFEAQQHNLQVEREKLYMEQQLKTFEQKCQELQQNLIQKEEEQEEFIEQLTEKETMLNE 852

Query: 1529 Q-----EIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDA 1583
            Q     E+++    +E +    +++   S  QK   +    KQ ++   D    K +L +
Sbjct: 853  QRNQIEELKLQFQKEEDSLNSEILQLQDSLKQKEKQYHIYQKQQKEYTQDKL--KGVLSS 910

Query: 1584 VPRAELDLAMY 1594
            +  A  DL ++
Sbjct: 911  LAEARQDLTIF 921



 Score =  103 bits (247), Expect = 4e-20
 Identities = 164/842 (19%), Positives = 373/842 (44%), Gaps = 70/842 (8%)

Query: 297  KQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEH-LNCQIRQTNKELENKLATMGTE 355
            KQ +E    +  E+E    L+   +  L  KIE  E  L   + ++ + + N+   +  +
Sbjct: 332  KQILEKLQMQTDEVERLKKLQQETIDTLQNKIEFNEKSLRDNLEESQRIIANQQVDIQYK 391

Query: 356  SKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQ 415
            ++ ++  S+K +  I+     + A +++    +  ++    D  +++  N  A LE  IQ
Sbjct: 392  NRQIAELSQKLTQSIT-----DHAKQLQLLAKEADAQ--RDDIQQELIANSNA-LENDIQ 443

Query: 416  SLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDV 475
             L   L   +   +               K+  I +L+ + +Q+     +  +    ED+
Sbjct: 444  DLKSQLTRIQNENTVLHDENKKLFYDSHSKENRIKELEGQIKQNQS--KINDLQQKLEDL 501

Query: 476  NEIAKVQEQLKQELNDEIKDV--NVKDLIEKLKSAEEQITQLND--EIDAANKNMIKVKS 531
            N+++   ++  + L+ + +    + K LI + +  E+ I  L D   +    +  +K+  
Sbjct: 502  NKLSNHLDEQNRSLDAQNQQFFNDNKALIAQTEEQEKAIQNLKDLETLHIQLQEKLKLIE 561

Query: 532  NHKLKLKQM-QKTIDNFSKVSDSNKEIVRLTE-ELHHLSQKVAELEEEKGNLQLHLVDYD 589
            + K  L Q  Q+ I+   K  +   E+ +  E E  +       L+E + +L++ +    
Sbjct: 562  SEKASLAQTAQQHIEESEKYKNQLFELQQGQEKEKRYALDGQMRLKENEVSLKIEV---- 617

Query: 590  SGRMIESDVYKKMIEMENLAETRLKAISLLE-------SQKFDLVQELHILQQKYDEVED 642
                 +S++    +  E    T+ K I  ++       S+K   ++ L  L +KY++ ++
Sbjct: 618  --ERQQSEIKHNQLLFEEKLSTKQKEIEFIQIQLNSTTSEKVKCLETLSELTKKYEQQKE 675

Query: 643  KLADISQLQSDQVCSEIKSVH--LEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLE 700
            KL D+ + Q  Q+ ++I ++   L+E+ +A   +  ++ L+ +  +  KEQ    ++ + 
Sbjct: 676  KLKDLQE-QKIQLEAKINNLEALLQEKNNAFEKTSIQIDLLTQESQTIKEQYNQKVRQIS 734

Query: 701  NDKEDIMNKLQNYIQENMDLTDKL-EKMSAEK--ISELLAKINHEEQSKIQ---TQFGID 754
              +E+I    ++  + N +L D L EK + EK  + +L  K +   Q + Q   TQ  + 
Sbjct: 735  LQEENISQYAKDNQKLNNELKDLLQEKNNVEKKLLLDLQQKTSEVAQLQQQIKATQKQLQ 794

Query: 755  AKIQERDLYIEN----IESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQ 810
             + Q+ +L +E     +E +L  ++ +   L++++   E+ +     +  +  + L E++
Sbjct: 795  FEAQQHNLQVEREKLYMEQQLKTFEQKCQELQQNLIQKEEEQEEFIEQLTEKETMLNEQR 854

Query: 811  KAYSEYTIQ----EDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQ 866
                E  +Q    ED L + +  L D  +  EKQ    + + KE  +      ++ + + 
Sbjct: 855  NQIEELKLQFQKEEDSLNSEILQLQDSLKQKEKQYHIYQKQQKEYTQ------DKLKGVL 908

Query: 867  ISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIE 926
             SL++ +Q       K N    +E   T  +T L+  +  ++    +   L VQ   E+E
Sbjct: 909  SSLAEARQDLTIFQSKCN----SEINDTHSRT-LQYFQDIMQFSREQKSKLKVQYDNEME 963

Query: 927  DLEIEFNTQIESAI-RDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVE-ELNKM 984
              +   +T+ E+ + +++ ++ E+     + ++ LE ++ E     +      + E+N +
Sbjct: 964  KYQENISTKFETQLDKERLIMRERESHFNKQISLLEQKVLEQNTRFQEEKQKYQQEINSL 1023

Query: 985  NLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVS 1044
                I + +Q    +      Q +   ++    +++  +++  +NQ    +QV Y +M+S
Sbjct: 1024 EERNITEKIQLNN-EIIQLKNQLLKVESRSARSVEKNQKQLEMVNQNAQKSQVMYANMIS 1082

Query: 1045 DYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKEL-KETKLTFE 1103
            D ++KL       E+ ++E+Q +++    SK HN +  +   E +D  ++L   T  T  
Sbjct: 1083 DIKNKLE------ESEKKELQVLNE--TRSKIHNMKAHLQQIELEDSNEQLAHSTSSTSS 1134

Query: 1104 MN 1105
            MN
Sbjct: 1135 MN 1136



 Score = 70.1 bits (164), Expect = 5e-10
 Identities = 158/851 (18%), Positives = 350/851 (41%), Gaps = 93/851 (10%)

Query: 154  KDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXED 213
            K+N +  L+ ++K  ++ I DLQ+K       +E  NK +                   D
Sbjct: 473  KENRIKELEGQIKQNQSKINDLQQK-------LEDLNKLSNHLDEQNRSLDAQNQQFFND 525

Query: 214  TKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSK 273
             K  + + +E   A++          LKD+E+  ++   L+E  KL+E+       E + 
Sbjct: 526  NKALIAQTEEQEKAIQN---------LKDLETLHIQ---LQEKLKLIES-------EKAS 566

Query: 274  LAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEH 333
            LAQ  +Q              L     +   E++      G + +    E++ KIE +E 
Sbjct: 567  LAQTAQQHIEESEKYKNQLFEL-----QQGQEKEKRYALDGQMRLKE-NEVSLKIE-VER 619

Query: 334  LNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSET 393
               +I+      E KL+T            +K    I  +    T+ K+K        ET
Sbjct: 620  QQSEIKHNQLLFEEKLST-----------KQKEIEFIQIQLNSTTSEKVK------CLET 662

Query: 394  LNQDTDK-KINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQL 452
            L++ T K +  K ++  L+     L   + + E ++ EK+             D L  + 
Sbjct: 663  LSELTKKYEQQKEKLKDLQEQKIQLEAKINNLEALLQEKNNAFEKTSIQI---DLLTQES 719

Query: 453  QLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVN--VKDLIEKLKSAEE 510
            Q   +Q+ +   +  +    E++++ AK  ++L  EL D +++ N   K L+  L+    
Sbjct: 720  QTIKEQYNQ--KVRQISLQEENISQYAKDNQKLNNELKDLLQEKNNVEKKLLLDLQQKTS 777

Query: 511  QITQLNDEIDAANKNMIKVKSNHKLKLKQ----MQKTIDNF-SKVSDSNKEIVRLTEE-- 563
            ++ QL  +I A  K +      H L++++    M++ +  F  K  +  + +++  EE  
Sbjct: 778  EVAQLQQQIKATQKQLQFEAQQHNLQVEREKLYMEQQLKTFEQKCQELQQNLIQKEEEQE 837

Query: 564  --LHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLES 621
              +  L++K   L E++  ++   + +      E  +  +++++++  + + K   + + 
Sbjct: 838  EFIEQLTEKETMLNEQRNQIEELKLQFQKE---EDSLNSEILQLQDSLKQKEKQYHIYQK 894

Query: 622  QKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVH---LEEQIDALSAS---K 675
            Q+ +  Q+   L+     + +   D++  QS +  SEI   H   L+   D +  S   K
Sbjct: 895  QQKEYTQDK--LKGVLSSLAEARQDLTIFQS-KCNSEINDTHSRTLQYFQDIMQFSREQK 951

Query: 676  KELALVIENLKLDKEQLYGTIKDLENDKED-IMNKLQNYIQENMDLTDKLEKMSAEKISE 734
             +L +  +N     ++   T  + + DKE  IM + +++  + + L +  +K+  +    
Sbjct: 952  SKLKVQYDNEMEKYQENISTKFETQLDKERLIMRERESHFNKQISLLE--QKVLEQNTRF 1009

Query: 735  LLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICR-LEESIAVMEDRRY 793
               K  ++++     +  I  KIQ  +  I+ ++++L K +SR  R +E++   +E    
Sbjct: 1010 QEEKQKYQQEINSLEERNITEKIQLNNEIIQ-LKNQLLKVESRSARSVEKNQKQLEMVNQ 1068

Query: 794  SLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKEL-- 851
            + ++      + + + +    E   +E +++N     + H+     Q +E+E  N++L  
Sbjct: 1069 NAQKSQVMYANMISDIKNKLEESEKKELQVLNETRSKI-HNMKAHLQQIELEDSNEQLAH 1127

Query: 852  --QKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKR 909
                 + +  + + N   S +++    N  ++      L +++ T      ++ E  +K 
Sbjct: 1128 STSSTSSMNKQNSNNDGRSSNNLNNTNNINIDSLQNNTLLQTQRTARLALQKEYEKTMKN 1187

Query: 910  ITHEHQTLI-VQKKKEIEDLEIEFNTQIESAIR--DKKVLNEKYEKNIEYVTQLEAQLQE 966
               +   +      K    L++  N+Q   +IR   K +    +   I Y     ++ Q+
Sbjct: 1188 FQKQEIPVSGNSSNKSNNSLQLS-NSQNNISIRGQSKSMQTNNFVDGINYTLGSTSKYQK 1246

Query: 967  YKNNIENLNMN 977
                I N  M+
Sbjct: 1247 SPQQITNSKMS 1257



 Score = 35.9 bits (79), Expect = 9.2
 Identities = 77/452 (17%), Positives = 188/452 (41%), Gaps = 29/452 (6%)

Query: 144  VTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXX 203
            + +L   ++EK+NA     +++ ++      ++E+ N+K + I  + +            
Sbjct: 691  INNLEALLQEKNNAFEKTSIQIDLLTQESQTIKEQYNQKVRQISLQEE----NISQYAKD 746

Query: 204  XXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAA 263
                    +D  Q+   +++  +    +   E  +L + I++   ++   E     L+  
Sbjct: 747  NQKLNNELKDLLQEKNNVEKKLLLDLQQKTSEVAQLQQQIKATQKQL-QFEAQQHNLQVE 805

Query: 264  RFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEI-EEKGSLEIANMT 322
            R ++ +E     +  EQ                ++ IE   E++T + E++  +E   + 
Sbjct: 806  REKLYMEQQ--LKTFEQKCQELQQNLIQKEEEQEEFIEQLTEKETMLNEQRNQIEELKL- 862

Query: 323  ELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKG---SPLISRKSGRNTA 379
            +  K+ + L     Q++ + K+ E +      + K  +    KG   S   +R+      
Sbjct: 863  QFQKEEDSLNSEILQLQDSLKQKEKQYHIYQKQQKEYTQDKLKGVLSSLAEARQDLTIFQ 922

Query: 380  SKMKSPWSQLSSETLNQDTD-KKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXX 438
            SK  S  +   S TL    D  + ++ + +KL+  +Q  N+    +E + ++ +T     
Sbjct: 923  SKCNSEINDTHSRTLQYFQDIMQFSREQKSKLK--VQYDNEMEKYQENISTKFETQLDKE 980

Query: 439  XXXXXGKDT-LIAQLQLEHQQHMEGPSLIHVGTN--TEDVNEIAKVQEQLKQELNDEIKD 495
                  +++    Q+ L  Q+ +E  +          +++N + +     K +LN+EI  
Sbjct: 981  RLIMRERESHFNKQISLLEQKVLEQNTRFQEEKQKYQQEINSLEERNITEKIQLNNEI-- 1038

Query: 496  VNVKDLIEKLKSAEEQITQLND-EIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSN 554
            + +K+ + K++S   +  + N  +++  N+N  K +  +   +  ++  ++   K     
Sbjct: 1039 IQLKNQLLKVESRSARSVEKNQKQLEMVNQNAQKSQVMYANMISDIKNKLEESEK----- 1093

Query: 555  KEIVRLTE---ELHHLSQKVAELEEEKGNLQL 583
            KE+  L E   ++H++   + ++E E  N QL
Sbjct: 1094 KELQVLNETRSKIHNMKAHLQQIELEDSNEQL 1125


>UniRef50_Q22TK4 Cluster: Putative uncharacterized protein; n=1;
            Tetrahymena thermophila SB210|Rep: Putative
            uncharacterized protein - Tetrahymena thermophila SB210
          Length = 2536

 Score =  126 bits (303), Expect = 7e-27
 Identities = 294/1482 (19%), Positives = 627/1482 (42%), Gaps = 141/1482 (9%)

Query: 159  SVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXE-DTKQQ 217
            + L  K++I +  + D  ++ +E  Q+ E K K                    + D K +
Sbjct: 305  NALDKKIQIKKAILKDENDQQHEA-QLKEIKEKYRQLVLKSKQQKLAFQKAFKQIDLKGK 363

Query: 218  MTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSL-EEANKLLEAARFEISLEHSKLAQ 276
            + +M+E   +M  + K+E  +   D+  K ++  SL  +  K +   R +   +  K+  
Sbjct: 364  LNEMREEIHSMIEQEKEESIQNFNDLAQKLLKEKSLNNQFQKEIRKLRSDNQEKDIKIQS 423

Query: 277  ELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKI-ELLEHLN 335
              E                 KQ  +    +  + +++ S      TEL  K+ EL + ++
Sbjct: 424  INEHTSTVERNQKEFYEKQLKQLQDKINSQTKKYQDEQSKSKQEQTELANKVKELQKQID 483

Query: 336  CQIRQT---NKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSE 392
             Q+ +      E+E K   M T+   + S +K+    I  K  +    K++    +  + 
Sbjct: 484  QQVAEIELFKSEIEEKDLLMKTQEDTIESRNKEIE--IKGKDLKTIQKKLQQ--KEQENN 539

Query: 393  TLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQL 452
            +LNQ    K  +N + + +   Q   ++L  ++ +I EK +           K+ L  QL
Sbjct: 540  SLNQQI--KEAQNSLQQKQEETQKNIENL--QQTIIKEKKSFQIE-------KEKLSQQL 588

Query: 453  QLEHQQHMEGPSLIHVGTN---TEDVNEIAKVQEQLKQELNDEIKDV--NVKDLIEKL-K 506
            Q E   ++E  +L     N   TE  N++ ++Q +   +  ++IK +    +  IEK+ K
Sbjct: 589  Q-EQLNNVENKTLTIQKLNQTVTELQNKLKQIQLESNNQSGNQIKQIRQEYEQKIEKIQK 647

Query: 507  SAEEQITQLNDE----IDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTE 562
              +EQI  +  E    I    +   K++S  K    Q QK  +   K +++ + I  L +
Sbjct: 648  EQQEQINLIKQENLKAISLLTQKDQKIESLQKQFNLQQQKLAEQIKKQNENQQLIQSLQQ 707

Query: 563  ELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQ 622
             L + ++   ++  E+ +LQ       + + +E + +  +   +  ++  LK IS  E+Q
Sbjct: 708  NLKNQNKFNNQIVNEQQDLQ-----ETNNQQLEDEYF--LSTQQKQSQDVLK-IS-KENQ 758

Query: 623  KFDLVQELH-ILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALV 681
              D  Q+ H I+QQ  ++++++  +  Q + +++   + S     Q +    +     L 
Sbjct: 759  FLDQNQDSHFIIQQNNEDIQNEEVN-HQFEQEEIFQNLSSNIQNNQEERDKCANNNNNLG 817

Query: 682  IENLKLDKEQLYGT-----IKDLENDKEDIMNKL--QNYIQENMDLTD------KLEKMS 728
            +E+L+++ E ++G      IK  E + ++ +N+L   N+IQ   + ++      +++   
Sbjct: 818  LEDLEIE-ENVWGNQNNSQIKQEEEEHDEKINQLNQDNFIQAKHERSEFQKEENEIQNKD 876

Query: 729  AEKISE-LLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAV 787
             EK  E L  + N  EQS  Q Q+        +DL+   ++ E       I  ++     
Sbjct: 877  QEKKYETLFEQNNFVEQSNNQQQY--------QDLFYNTVKQE------EISPIKMQQQN 922

Query: 788  MEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEH- 846
              D  +  +++ + + S  Q+ Q      ++ +D+  N+  ++ + D++ ++Q  + E  
Sbjct: 923  NFDAVFGNQKQQENIFSNFQQNQNG----SLNKDQNANQ-QLVSNIDQIQQQQHQQNEDI 977

Query: 847  --ENKELQKKNQILLEENQNLQ---ISLSDMQQHYNALVEKANRTD-LAESESTKYQTQL 900
               + ++++ +QI ++ +QN Q    S +++QQ+   L E + +   + ++E  + Q Q 
Sbjct: 978  AINHSQIEELSQIKVQNDQNNQQTSSSQNELQQNNPGLSESSLKDQTIQQNEEFQVQKQQ 1037

Query: 901  RD------LESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQI-ESAIRDKKVLNEKYEKN 953
             D      L+  +   T  +Q    +KKK+           + E +    + +NE  +  
Sbjct: 1038 HDENKLDALDLLMNNNTQTNQPSKKKKKKKKGKTNSNAPVNLFEESTPQNEFINESSQNE 1097

Query: 954  IEYVTQLEAQLQEYKNNIE--NLNMNVEELNKMNLEL-IDKHVQKQQTQSPDYTEQYINE 1010
            ++    L++ +Q  K+N +   L    +E ++ N +   D    + + ++ ++  Q+ N 
Sbjct: 1098 LKI---LDSSMQSNKSNKDQKQLEKQQDEQSQNNKQAQKDNFYNQFEVKNENWENQFFNT 1154

Query: 1011 INKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQ 1070
              K N     KD   I+ NQ+ NNA  +    +S ++SK  Q   K+ N       + K 
Sbjct: 1155 A-KQNIQDAFKD---ISKNQQQNNASKNQNQQIS-FDSKADQSFDKVLN-----NSIDKN 1204

Query: 1071 LLDSKQHNEELQILVR-EQDDQIKELKET--KLTF----EMNIPKTE-GMIISSTIE-PM 1121
             L  K  NE  Q  +R  Q+D    ++E   KLTF    E+N+ +   G+ + S  E   
Sbjct: 1205 NLQKKNLNEREQTQIRNNQEDLFSNIQENKQKLTFQNIEELNVEEDAWGIQVESPKEIEQ 1264

Query: 1122 SDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETL 1181
                N V             +K    +  ++ +S  Q +    N  +Q+ +   IQ +  
Sbjct: 1265 QGKQNEVPKESIQRDNEHAEIKNDTFQSKLESQSFFQVEQ---NNNVQKIFE--IQNDFF 1319

Query: 1182 NTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQ 1241
            +     +    Q++  + +SK+ +  T+N  +L +  +L  +  ++  Q       L  Q
Sbjct: 1320 SQINQQNQQDKQQKDEKQESKINKNETQNVQILISDVDLDDNWGTSQPQNDSNDNNLKTQ 1379

Query: 1242 HLAQ---READFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNK 1298
             + +     +D + ++H+  +  S+ + ++   L   +++ Q + +K+  ++ + S  N+
Sbjct: 1380 AIIESKLNNSDLKSSKHKEELDQSSKQDEFS--LKEQKNAQQIQEHKLDILDLLMSNNNQ 1437

Query: 1299 LQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQS 1358
               +    +   +K  +V NQ   L  E   +                     ++   + 
Sbjct: 1438 QTGQTVKKKKKSKKAKNVNNQSLNLFEENTPQSTQQNETSQNDIKNLDNSIQSIKQNKEQ 1497

Query: 1359 YKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQ 1418
             KQ   ++I N ++ N QL  S+            + N  + ++     Q E K  +I  
Sbjct: 1498 KKQASSENIENNSDLNQQLNTSTQKGSLEKLNEDKQDNCQKEQI--AFEQSENKIIDI-N 1554

Query: 1419 KTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQK 1478
            K  +  I  T   +E +   Q++ + E+  E++  E ++E  I  +K     ++ E  Q 
Sbjct: 1555 KNDQSEIQ-TDNKEELQQENQRIHQIEE--ENVHQESQAE-NIQEIKF----DNIEVNQT 1606

Query: 1479 ESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAK-TNEMQTALENQEIEIVTLN 1537
            E+E ++++LIEE+ + I  +    +Q     K L++E  +  +E      NQEI+  T  
Sbjct: 1607 ENEQKQLELIEEIQIDIEINQQQQRQEEMQIKDLKQENNQIVSEENQINVNQEID--TQV 1664

Query: 1538 DEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKE 1579
            ++  N +N     +S  Q   ++     + ++ Q  N  N++
Sbjct: 1665 EQAINQENDDINQNSNNQIQFTYQEQDNKEQNNQEINEANQQ 1706



 Score =  121 bits (292), Expect = 1e-25
 Identities = 265/1348 (19%), Positives = 563/1348 (41%), Gaps = 126/1348 (9%)

Query: 220  KMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELE 279
            K QEN  +   +  ++   L KD  +    +S++++  +       +I++ HS++ +EL 
Sbjct: 932  KQQENIFSNFQQ--NQNGSLNKDQNANQQLVSNIDQIQQQQHQQNEDIAINHSQI-EELS 988

Query: 280  QXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKG-SLEIANMTELTKKIELLEHLNCQI 338
            Q                 Q+ + +   + E+++    L  +++ + T  I+  E    Q 
Sbjct: 989  QIKVQND-----------QNNQQTSSSQNELQQNNPGLSESSLKDQT--IQQNEEFQVQK 1035

Query: 339  RQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDT 398
            +Q ++   + L  +   +   + PSKK      +K G+  ++   +P +     T   + 
Sbjct: 1036 QQHDENKLDALDLLMNNNTQTNQPSKKKK---KKKKGKTNSN---APVNLFEESTPQNEF 1089

Query: 399  DKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQ 458
              + ++NE+  L+  +QS NK   D++ +  EK             KD    Q +++++ 
Sbjct: 1090 INESSQNELKILDSSMQS-NKSNKDQKQL--EKQQDEQSQNNKQAQKDNFYNQFEVKNE- 1145

Query: 459  HMEGPSLIHVGTNTEDV-NEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLND 517
            + E         N +D   +I+K Q+Q     N+  K+ N +   +  K+ +     LN+
Sbjct: 1146 NWENQFFNTAKQNIQDAFKDISKNQQQ-----NNASKNQNQQISFDS-KADQSFDKVLNN 1199

Query: 518  EIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIV-RLTEELHHLSQKVAELEE 576
             ID  N     +    + +++  Q+  D FS + ++ +++  +  EEL+        +EE
Sbjct: 1200 SIDKNNLQKKNLNEREQTQIRNNQE--DLFSNIQENKQKLTFQNIEELN--------VEE 1249

Query: 577  EKGNLQLHLVDYDSGRMIESDVYKKMIEMENL-AETRLKAI-SLLESQKFDLVQELHILQ 634
            +   +Q+        +  +++V K+ I+ +N  AE +     S LESQ F  V++ + +Q
Sbjct: 1250 DAWGIQVESPKEIEQQGKQNEVPKESIQRDNEHAEIKNDTFQSKLESQSFFQVEQNNNVQ 1309

Query: 635  QKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYG 694
            + ++   D  + I+Q   +Q   + K    E +I+      + + ++I ++ LD    +G
Sbjct: 1310 KIFEIQNDFFSQINQ--QNQQDKQQKDEKQESKIN--KNETQNVQILISDVDLDDN--WG 1363

Query: 695  TIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGID 754
            T +  +ND  D   K Q  I+  ++ +D       E++ +   +     + +   Q   +
Sbjct: 1364 TSQP-QNDSNDNNLKTQAIIESKLNNSDLKSSKHKEELDQSSKQDEFSLKEQKNAQQIQE 1422

Query: 755  AKIQERDLYIENIESELS-----KYKSRICRL--EESIAVMEDRRYSLERKADQLGSYLQ 807
             K+   DL + N   +       K KS+  +    +S+ + E+      ++ +   + ++
Sbjct: 1423 HKLDILDLLMSNNNQQTGQTVKKKKKSKKAKNVNNQSLNLFEENTPQSTQQNETSQNDIK 1482

Query: 808  EKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQI 867
                +       +++     +  ++++  + +QL     +   L+K N+   +  Q  QI
Sbjct: 1483 NLDNSIQSIKQNKEQKKQASSENIENNSDLNQQL-NTSTQKGSLEKLNEDKQDNCQKEQI 1541

Query: 868  SLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHE--HQTLIVQKKKEI 925
            +    +Q  N +++  N+ D +E + T  + +L+     + +I  E  HQ    +  +EI
Sbjct: 1542 AF---EQSENKIID-INKNDQSEIQ-TDNKEELQQENQRIHQIEEENVHQESQAENIQEI 1596

Query: 926  EDLEIEFNTQIESAIRDKKVLNE---KYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELN 982
            +   IE N Q E+  +  +++ E     E N +   Q E Q+++ K   EN N  V E N
Sbjct: 1597 KFDNIEVN-QTENEQKQLELIEEIQIDIEINQQQQRQEEMQIKDLKQ--EN-NQIVSEEN 1652

Query: 983  KMNL-ELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMS 1041
            ++N+ + ID  V++   Q  D   Q  N  N++    +++D +    NQ+IN A     +
Sbjct: 1653 QINVNQEIDTQVEQAINQENDDINQ--NSNNQIQFTYQEQDNKE-QNNQEINEANQQQDT 1709

Query: 1042 MVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLT 1101
               + E          EN+E++ Q   ++     Q +      V+ Q+D  + L++ +  
Sbjct: 1710 EEGNIEQTALINQGLAENIEDQSQEQKQEEFKLSQDD------VQGQEDLGENLQDNQKV 1763

Query: 1102 FEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQS 1161
             E    + +        E       N++             ++ +EEE      V Q QS
Sbjct: 1764 QEFKQSEDDETDDKKDQEIQQKSNENIEIIQDNLEDQQEVNQINQEEEL----DVKQNQS 1819

Query: 1162 AKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELR 1221
              L+ EL E        E  N+E+  H  V + QINQ++ K      EN + L      +
Sbjct: 1820 -NLDQELNE-------REIQNSEVQNHQDVQENQINQIEKKNSNEQLENQSELQAAQGNK 1871

Query: 1222 SSISSAVDQRGFEIAELWKQHLAQREAD-----FQKTEHELRVQLSAFESKYEQLLDSVQ 1276
                S  D++     ++    + Q+E D      Q   ++++V L+      +Q  +S++
Sbjct: 1872 HQEFS--DEQNDNQDQINDDQILQQEQDEKIDLSQANNNDIQVDLN--NQIEDQKRNSLK 1927

Query: 1277 SSTQEETNKIVTMEQVTSLQNKLQDKEEH--LRNLQEKYADVINQIEILRSEIEDEKVAF 1334
             +  E+  + +  E     +N ++DKEE   +++ +E+  ++I Q       IE ++   
Sbjct: 1928 ENLVEDKQEEILFEDKQE-ENLVEDKEEENLVQDKEEENVEIIQQENENNQNIEQQQ--- 1983

Query: 1335 XXXXXXXXXXXXXXXXDLRTENQSYKQMQE---QSILNINEENAQLKKSSXXXXXXXXXX 1391
                            + + E Q +KQ QE    S    NE   Q ++ +          
Sbjct: 1984 DQNVNQFENNQEQNTFEDQNEQQQFKQEQEVLDNSEQIKNEIQQQQQQQTESIDSNQDNQ 2043

Query: 1392 XXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDL 1451
              ++   E K LE   Q E  D +I ++ +   +   Q + + ++  Q +    +++E+ 
Sbjct: 2044 QLQIKSEEQKELEYELQNE-DDQKIEEQQNNQQVDKAQ-SQQIQHEEQNMNAQLEQLEEN 2101

Query: 1452 TYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKA 1511
              E ++       +  EN +HY    +  + ++ K + E      E     K +   N+ 
Sbjct: 2102 PVELQTNQLESNGQNEENIDHYNLETENLDNQKEKELHE------EQTQEEKPIE--NQQ 2153

Query: 1512 LEEEVAKTNEMQTALENQEIEIVTLNDE 1539
             E+E  + N+ +  ++ ++IEI +   E
Sbjct: 2154 NEDENQQLNQKENNIQKEDIEITSQTKE 2181



 Score =  101 bits (242), Expect = 2e-19
 Identities = 179/870 (20%), Positives = 392/870 (45%), Gaps = 96/870 (11%)

Query: 475  VNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQ--ITQLN-DEIDAANKNMIKVKS 531
            +  I + +EQ KQ  ++ I+  N  DL ++L ++ ++  + +LN D+ D   K  I  + 
Sbjct: 1488 IQSIKQNKEQKKQASSENIE--NNSDLNQQLNTSTQKGSLEKLNEDKQDNCQKEQIAFEQ 1545

Query: 532  NHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSG 591
            +   K+  + K  ++ S++   NKE      EL   +Q++ ++EEE        V  +S 
Sbjct: 1546 SEN-KIIDINK--NDQSEIQTDNKE------ELQQENQRIHQIEEEN-------VHQESQ 1589

Query: 592  RMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQ 651
                 ++    IE+ N  E   K + L+E  + D+  E++  QQ+ +E++ K  D+ Q +
Sbjct: 1590 AENIQEIKFDNIEV-NQTENEQKQLELIEEIQIDI--EINQQQQRQEEMQIK--DLKQ-E 1643

Query: 652  SDQVCSEIKSVHLEEQIDAL--SASKKELALVIENLKLDKEQLYGTIKDLENDKEDI--M 707
            ++Q+ SE   +++ ++ID     A  +E   + +N     +  Y    + E + ++I   
Sbjct: 1644 NNQIVSEENQINVNQEIDTQVEQAINQENDDINQNSNNQIQFTYQEQDNKEQNNQEINEA 1703

Query: 708  NKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEE----QSKIQTQFGIDAKIQERDLY 763
            N+ Q+  + N++ T  + +  AE I +   +   EE    Q  +Q Q  +   +Q+    
Sbjct: 1704 NQQQDTEEGNIEQTALINQGLAENIEDQSQEQKQEEFKLSQDDVQGQEDLGENLQDNQKV 1763

Query: 764  -----IENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSY--LQEKQKAYS-E 815
                  E+ E++  K +    +  E+I +++D     +++ +Q+     L  KQ   + +
Sbjct: 1764 QEFKQSEDDETDDKKDQEIQQKSNENIEIIQDNLED-QQEVNQINQEEELDVKQNQSNLD 1822

Query: 816  YTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQ-NLQISLSDMQQ 874
              + E E+ N  + + +H  V E Q+ +IE +N   Q +NQ  L+  Q N     SD Q 
Sbjct: 1823 QELNEREIQN--SEVQNHQDVQENQINQIEKKNSNEQLENQSELQAAQGNKHQEFSDEQN 1880

Query: 875  HYNALV--------EKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIE 926
                 +        E+  + DL+++ +   Q  L +   + KR + + + L+  K++EI 
Sbjct: 1881 DNQDQINDDQILQQEQDEKIDLSQANNNDIQVDLNNQIEDQKRNSLK-ENLVEDKQEEIL 1939

Query: 927  DLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNL 986
              + +    +E    ++ ++ +K E+N+E + Q     Q  +   ++ N+N  E N+   
Sbjct: 1940 FEDKQEENLVEDK-EEENLVQDKEEENVEIIQQENENNQNIEQQ-QDQNVNQFENNQEQN 1997

Query: 987  ELIDKHVQ---KQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMV 1043
               D++ Q   KQ+ +  D +EQ  NEI +     +Q+  E I  NQ  +N Q+     +
Sbjct: 1998 TFEDQNEQQQFKQEQEVLDNSEQIKNEIQQQ----QQQQTESIDSNQ--DNQQLQ----I 2047

Query: 1044 SDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFE 1103
               E K  ++  + E+ ++  ++ + Q +D  Q ++++Q   +  + Q+++L+E  +  +
Sbjct: 2048 KSEEQKELEYELQNEDDQKIEEQQNNQQVDKAQ-SQQIQHEEQNMNAQLEQLEENPVELQ 2106

Query: 1104 MNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAK 1163
             N  ++ G      I+  + +  N+D             K   EE+  +E+ +  +Q+  
Sbjct: 2107 TNQLESNGQN-EENIDHYNLETENLDNQKE---------KELHEEQTQEEKPIENQQNED 2156

Query: 1164 LNTELQECYTKIIQLETLNTELTGHDVVNQ-EQINQLKSKLEQLNTENDNLLSTVAELRS 1222
             N +L +    I + +   T  T  +   + ++ + L       N  +D+L+      + 
Sbjct: 2157 ENQQLNQKENNIQKEDIEITSQTKEEKPKELDEDDLLNEDAGWGNQNDDSLIQEDQNWKV 2216

Query: 1223 SISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEE 1282
              +    ++  ++ ++++    Q++   QK            +S  +++     S+ QE+
Sbjct: 2217 EENEPQIEKDIQVNDIFENLTEQKD---QKLN----------DSNQDEINCDQHSNNQEQ 2263

Query: 1283 TNKIVTMEQVTSLQNKLQDKEEHLRNLQEK 1312
                   ++  S  N  ++KE+ + N+ E+
Sbjct: 2264 QQISENPQKECSNNNLQEEKEDKITNVNEE 2293



 Score = 98.3 bits (234), Expect = 2e-18
 Identities = 291/1578 (18%), Positives = 657/1578 (41%), Gaps = 142/1578 (8%)

Query: 57   AQKCLENAALVSKRIKEHRKATAELLGRPF-VPGISESLANTLKQKEILMEKIKQYKELS 115
            AQK L+  +L ++  KE RK  ++   +   +  I+E  +   + ++   EK  Q K+L 
Sbjct: 390  AQKLLKEKSLNNQFQKEIRKLRSDNQEKDIKIQSINEHTSTVERNQKEFYEK--QLKQLQ 447

Query: 116  KRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNALSVLQVKMKIMETTILDL 175
             + ++   +                  + T L+N +KE    +     ++++ ++ I + 
Sbjct: 448  DKINSQTKKYQDEQSKSKQ--------EQTELANKVKELQKQIDQQVAEIELFKSEIEEK 499

Query: 176  QEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDE 235
               +  ++  IE++NK                       K+   K QEN  ++  + K+ 
Sbjct: 500  DLLMKTQEDTIESRNKEIEIKGKDLKTIQ----------KKLQQKEQENN-SLNQQIKEA 548

Query: 236  KQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXL 295
            +  L +  E     I +L++   + E   F+I  E  KL+Q+L++              L
Sbjct: 549  QNSLQQKQEETQKNIENLQQTI-IKEKKSFQI--EKEKLSQQLQEQLNNVENKTLTIQKL 605

Query: 296  AKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTE 355
              Q++     +  +I+ + + +  N  +     ++ +    +I +  KE + ++  +  E
Sbjct: 606  -NQTVTELQNKLKQIQLESNNQSGNQIK-----QIRQEYEQKIEKIQKEQQEQINLIKQE 659

Query: 356  S-KAVSSPSKKGSPLISRKSGRNTASKM------KSPWSQLSSETLNQDTDKKINK--NE 406
            + KA+S  ++K   + S +   N   +       K   +Q   ++L Q+  K  NK  N+
Sbjct: 660  NLKAISLLTQKDQKIESLQKQFNLQQQKLAEQIKKQNENQQLIQSLQQNL-KNQNKFNNQ 718

Query: 407  IAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLI 466
            I   +  +Q  N   ++ EY +S +             ++  + Q Q  H    +    I
Sbjct: 719  IVNEQQDLQETNNQQLEDEYFLSTQQKQSQDVLKISK-ENQFLDQNQDSHFIIQQNNEDI 777

Query: 467  HVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDA---AN 523
                  E+VN   + QE++ Q L+  I+  N ++  +K  +    +   + EI+     N
Sbjct: 778  Q----NEEVNHQFE-QEEIFQNLSSNIQ--NNQEERDKCANNNNNLGLEDLEIEENVWGN 830

Query: 524  KNMIKVKSN---HKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGN 580
            +N  ++K     H  K+ Q+ +  DNF +      E  +   E+ +  Q   E + E   
Sbjct: 831  QNNSQIKQEEEEHDEKINQLNQ--DNFIQAKHERSEFQKEENEIQNKDQ---EKKYETLF 885

Query: 581  LQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEV 640
             Q + V+  + +    D++   ++ E ++  +++  +  ++   +  Q+ +I    + + 
Sbjct: 886  EQNNFVEQSNNQQQYQDLFYNTVKQEEISPIKMQQQNNFDAVFGNQKQQENIFSN-FQQN 944

Query: 641  EDKLADISQLQSDQVCSEIKSV----HLEEQIDALSASK-KELALVIENLKLDKEQLYGT 695
            ++   +  Q  + Q+ S I  +    H + +  A++ S+ +EL+ +      + +Q   +
Sbjct: 945  QNGSLNKDQNANQQLVSNIDQIQQQQHQQNEDIAINHSQIEELSQIKVQNDQNNQQTSSS 1004

Query: 696  IKDLENDKEDIM-NKLQNY-IQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGI 753
              +L+ +   +  + L++  IQ+N +   + ++    K+  L   +N+  Q+   ++   
Sbjct: 1005 QNELQQNNPGLSESSLKDQTIQQNEEFQVQKQQHDENKLDALDLLMNNNTQTNQPSKKKK 1064

Query: 754  DAKIQERDLYIE-NIESELSKYKSRICRLEES-IAVMEDRRYSLERKADQLGSYLQEKQK 811
              K  + +     N+  E +     I    ++ + +++    S +   DQ     Q+ ++
Sbjct: 1065 KKKKGKTNSNAPVNLFEESTPQNEFINESSQNELKILDSSMQSNKSNKDQKQLEKQQDEQ 1124

Query: 812  AYSEYTIQEDELVNRLAVLMDH--DRVVEKQLLEIEHENKELQK-KNQILLEENQNLQIS 868
            + +    Q+D   N+  V  ++  ++        I+   K++ K + Q    +NQN QIS
Sbjct: 1125 SQNNKQAQKDNFYNQFEVKNENWENQFFNTAKQNIQDAFKDISKNQQQNNASKNQNQQIS 1184

Query: 869  L-SDMQQHYNALVEKA-NRTDLAESE-STKYQTQLRDLESNL-KRITHEHQTLIVQKKKE 924
              S   Q ++ ++  + ++ +L +   + + QTQ+R+ + +L   I    Q L  Q  +E
Sbjct: 1185 FDSKADQSFDKVLNNSIDKNNLQKKNLNEREQTQIRNNQEDLFSNIQENKQKLTFQNIEE 1244

Query: 925  IEDLEIEFNTQIESA--IRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELN 982
            +   E  +  Q+ES   I  +   NE  +++I    Q + +  E KN  +     +E  +
Sbjct: 1245 LNVEEDAWGIQVESPKEIEQQGKQNEVPKESI----QRDNEHAEIKN--DTFQSKLESQS 1298

Query: 983  KMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKIN-NAQVSYMS 1041
               +E  + +VQK      D+  Q IN+ N+ +   +QKDE+      KIN N   +   
Sbjct: 1299 FFQVEQ-NNNVQKIFEIQNDFFSQ-INQQNQQDK--QQKDEK---QESKINKNETQNVQI 1351

Query: 1042 MVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQD-DQIKELKETKL 1100
            ++SD +      T++ +N   +    ++ +++SK +N +L+    +++ DQ  +  E  L
Sbjct: 1352 LISDVDLDDNWGTSQPQNDSNDNNLKTQAIIESKLNNSDLKSSKHKEELDQSSKQDEFSL 1411

Query: 1101 TFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQ 1160
              + N  + +   +      MS+  NN                 Q+  + ++++    ++
Sbjct: 1412 KEQKNAQQIQEHKLDILDLLMSN--NN-----------------QQTGQTVKKKKK-SKK 1451

Query: 1161 SAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQ-INQLKSKLEQLNTENDNLLSTVAE 1219
            +  +N +    + +     T   E + +D+ N +  I  +K   EQ    +   +   ++
Sbjct: 1452 AKNVNNQSLNLFEENTPQSTQQNETSQNDIKNLDNSIQSIKQNKEQKKQASSENIENNSD 1511

Query: 1220 LRSSISSAVDQRGFEIAELWKQHLAQREA-DFQKTEHELRVQLSAFESKYEQLLDSVQSS 1278
            L   ++++  +   E     KQ   Q+E   F+++E+++ + ++    K +Q    +Q+ 
Sbjct: 1512 LNQQLNTSTQKGSLEKLNEDKQDNCQKEQIAFEQSENKI-IDIN----KNDQ--SEIQTD 1564

Query: 1279 TQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQE-KYADV-INQIEILRSEIE--DEKVAF 1334
             +EE  +    +++  ++ +   +E    N+QE K+ ++ +NQ E  + ++E  +E    
Sbjct: 1565 NKEELQQ--ENQRIHQIEEENVHQESQAENIQEIKFDNIEVNQTENEQKQLELIEEIQID 1622

Query: 1335 XXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEE-NAQLKKS---SXXXXXXXXX 1390
                            DL+ EN     + E++ +N+N+E + Q++++             
Sbjct: 1623 IEINQQQQRQEEMQIKDLKQENNQI--VSEENQINVNQEIDTQVEQAINQENDDINQNSN 1680

Query: 1391 XXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDE--FENVRQQLVEYEKRI 1448
               +    E    E  +Q E+ ++   Q T E  I  T   ++   EN+  Q  E ++  
Sbjct: 1681 NQIQFTYQEQDNKEQNNQ-EINEANQQQDTEEGNIEQTALINQGLAENIEDQSQEQKQEE 1739

Query: 1449 EDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQ---- 1504
              L+ +       L   + +N    E  Q E +    K  +E+  K  E++ + +     
Sbjct: 1740 FKLSQDDVQGQEDLGENLQDNQKVQEFKQSEDDETDDKKDQEIQQKSNENIEIIQDNLED 1799

Query: 1505 VAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDT 1564
              E+N+  +EE     + Q+ L+ +  E    N E+ N Q++     ++I+K  S     
Sbjct: 1800 QQEVNQINQEEELDVKQNQSNLDQELNEREIQNSEVQNHQDVQENQINQIEKKNSNEQLE 1859

Query: 1565 KQGRDEQLDNTMNKELLD 1582
             Q   +      ++E  D
Sbjct: 1860 NQSELQAAQGNKHQEFSD 1877



 Score = 93.5 bits (222), Expect = 4e-17
 Identities = 227/1173 (19%), Positives = 477/1173 (40%), Gaps = 124/1173 (10%)

Query: 473  EDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSN 532
            + +    K  +Q K EL+   ++ N  D  +      E      +  D+ N   I     
Sbjct: 134  QQIQHANKGGQQKKDELDVVEEESNNCDESQIQNQIREYQNNSKNNYDSLN---INDGFQ 190

Query: 533  HKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGR 592
             + + KQ+ + +  F     S  +     E+         E +E+K N Q      +   
Sbjct: 191  QQFQQKQVNEKMQGFGGAKQSQSQNAFNQEKKVQKDNLFQEQQEKKQNDQKKQKQKNIEF 250

Query: 593  MIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQ----ELHILQQKYD-EVEDKLADI 647
             +E    +++ EM+NL         L    + + +Q    +L + Q+  D ++++K A  
Sbjct: 251  SLE--YVRQISEMQNLLNQEKLEFQLSLQARQNHIQMWEEDLKLRQEALDRQLDEKNALD 308

Query: 648  SQLQSDQ-VCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDI 706
             ++Q  + +  +      E Q+  +    ++L L  +  KL  ++ +  I DL+    ++
Sbjct: 309  KKIQIKKAILKDENDQQHEAQLKEIKEKYRQLVLKSKQQKLAFQKAFKQI-DLKGKLNEM 367

Query: 707  MNKLQNYI-QENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIE 765
              ++ + I QE  +       ++ + + E    +N++ Q +I+    + +  QE+D+ I+
Sbjct: 368  REEIHSMIEQEKEESIQNFNDLAQKLLKE--KSLNNQFQKEIRK---LRSDNQEKDIKIQ 422

Query: 766  NIESELSKYKSRICRL-EESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELV 824
            +I    S  +       E+ +  ++D+  S  +K      Y  E+ K+  E T    EL 
Sbjct: 423  SINEHTSTVERNQKEFYEKQLKQLQDKINSQTKK------YQDEQSKSKQEQT----ELA 472

Query: 825  NRLAVLMDH--DRVVEKQLLEIEHENKELQKKNQ--ILLEENQNLQISLSDMQQHYNALV 880
            N++  L      +V E +L + E E K+L  K Q   +   N+ ++I   D++     L 
Sbjct: 473  NKVKELQKQIDQQVAEIELFKSEIEEKDLLMKTQEDTIESRNKEIEIKGKDLKTIQKKLQ 532

Query: 881  EKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAI 940
            +K    +    +  + Q  L+  +   ++     Q  I+++KK  +  + + + Q++  +
Sbjct: 533  QKEQENNSLNQQIKEAQNSLQQKQEETQKNIENLQQTIIKEKKSFQIEKEKLSQQLQEQL 592

Query: 941  RDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMN-VEELNKMNLELIDKHVQKQQTQ 999
             + +      +K  + VT+L+ +L++ +    N + N ++++ +   + I+K +QK+Q +
Sbjct: 593  NNVENKTLTIQKLNQTVTELQNKLKQIQLESNNQSGNQIKQIRQEYEQKIEK-IQKEQQE 651

Query: 1000 SPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLEN 1059
              +  +Q   E  K  +LL QKD++I +L ++ N  Q            KLA+   K   
Sbjct: 652  QINLIKQ---ENLKAISLLTQKDQKIESLQKQFNLQQ-----------QKLAEQIKKQNE 697

Query: 1060 MEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIE 1119
             ++ +Q + + L +  + N +   +V EQ D    L+ET      N  + E     ST +
Sbjct: 698  NQQLIQSLQQNLKNQNKFNNQ---IVNEQQD----LQET------NNQQLEDEYFLSTQQ 744

Query: 1120 PMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQ-ECYTKIIQL 1178
              S D                 LK+ +E +F+ +         + N ++Q E      + 
Sbjct: 745  KQSQDV----------------LKISKENQFLDQNQDSHFIIQQNNEDIQNEEVNHQFEQ 788

Query: 1179 ETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTV--AELRSSISSAVDQRGFEIA 1236
            E +   L+ +   NQE+ ++  +    L  E+  +   V   +  S I    ++   +I 
Sbjct: 789  EEIFQNLSSNIQNNQEERDKCANNNNNLGLEDLEIEENVWGNQNNSQIKQEEEEHDEKIN 848

Query: 1237 ELWKQHLAQ---READFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQV- 1292
            +L + +  Q     ++FQK E+E  +Q    E KYE L +  Q++  E++N     + + 
Sbjct: 849  QLNQDNFIQAKHERSEFQKEENE--IQNKDQEKKYETLFE--QNNFVEQSNNQQQYQDLF 904

Query: 1293 --TSLQNKLQD-KEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXX 1349
              T  Q ++   K +   N    + +   Q  I  +  +++  +                
Sbjct: 905  YNTVKQEEISPIKMQQQNNFDAVFGNQKQQENIFSNFQQNQNGSLNKDQNANQQLVSNID 964

Query: 1350 XDLRTENQSYKQMQEQSILNIN-EENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQ 1408
               + + Q ++Q ++ +I +   EE +Q+K  +             +      + E +  
Sbjct: 965  ---QIQQQQHQQNEDIAINHSQIEELSQIKVQNDQNNQQTSSSQNELQQNNPGLSESS-- 1019

Query: 1409 LELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHE 1468
              LKD  I Q+  E+ +   Q ++   +    L+    +    + +K+ +    + K + 
Sbjct: 1020 --LKDQTI-QQNEEFQVQKQQHDENKLDALDLLMNNNTQTNQPSKKKKKK---KKGKTNS 1073

Query: 1469 NA--NHYETMQKESEIERVKLIEELNV--KITESVSLNKQVAELNKALEEEVAKTNEMQT 1524
            NA  N +E    ++E        EL +     +S   NK   +L K  +E+     + Q 
Sbjct: 1074 NAPVNLFEESTPQNEFINESSQNELKILDSSMQSNKSNKDQKQLEKQQDEQSQNNKQAQK 1133

Query: 1525 -------ALENQEIEIVTLNDEITNLQ--------NMVRASSSKIQ-KHVSFASDTKQGR 1568
                    ++N+  E    N    N+Q        N  + ++SK Q + +SF S   Q  
Sbjct: 1134 DNFYNQFEVKNENWENQFFNTAKQNIQDAFKDISKNQQQNNASKNQNQQISFDSKADQSF 1193

Query: 1569 DEQLDNTMNKELLDAVPRAELDLAMYMLHQRDV 1601
            D+ L+N+++K  L      E +      +Q D+
Sbjct: 1194 DKVLNNSIDKNNLQKKNLNEREQTQIRNNQEDL 1226



 Score = 91.5 bits (217), Expect = 2e-16
 Identities = 303/1554 (19%), Positives = 637/1554 (40%), Gaps = 175/1554 (11%)

Query: 153  EKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXE 212
            EK+     LQ ++  +E   L +Q K+N+   + E +NK                    +
Sbjct: 580  EKEKLSQQLQEQLNNVENKTLTIQ-KLNQT--VTELQNKLKQIQLESNNQSGNQIKQIRQ 636

Query: 213  DTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLE---AARFEISL 269
            + +Q++ K+Q+         K E  + +  +  KD +I SL++   L +   A + +   
Sbjct: 637  EYEQKIEKIQKEQQEQINLIKQENLKAISLLTQKDQKIESLQKQFNLQQQKLAEQIKKQN 696

Query: 270  EHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIE------EKGSLEIANMTE 323
            E+ +L Q L+Q                +Q ++ +  ++ E E      +K S ++  +++
Sbjct: 697  ENQQLIQSLQQNLKNQNKFNNQIVN-EQQDLQETNNQQLEDEYFLSTQQKQSQDVLKISK 755

Query: 324  LTKKIELLEHLNCQIRQTNKELENKLATMGTESKAV----SSPSKKGSPLISRKSGRNTA 379
              + ++  +  +  I+Q N++++N+      E + +    SS  +       + +  N  
Sbjct: 756  ENQFLDQNQDSHFIIQQNNEDIQNEEVNHQFEQEEIFQNLSSNIQNNQEERDKCANNNNN 815

Query: 380  SKMK------SPWSQLSSETLNQDT---DKKIN-------------KNEIAKLEMVIQSL 417
              ++      + W   ++  + Q+    D+KIN             ++E  K E  IQ  
Sbjct: 816  LGLEDLEIEENVWGNQNNSQIKQEEEEHDEKINQLNQDNFIQAKHERSEFQKEENEIQ-- 873

Query: 418  NKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEH----QQHMEGPSLIHVGTNTE 473
            NKD   K   + E++            +D     ++ E     +   +       G   +
Sbjct: 874  NKDQEKKYETLFEQNNFVEQSNNQQQYQDLFYNTVKQEEISPIKMQQQNNFDAVFGNQKQ 933

Query: 474  DVNEIAKVQEQLKQELNDEIKDVNV-KDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSN 532
              N  +  Q+     LN   KD N  + L+  +   ++Q  Q N++I A N + I+  S 
Sbjct: 934  QENIFSNFQQNQNGSLN---KDQNANQQLVSNIDQIQQQQHQQNEDI-AINHSQIEELSQ 989

Query: 533  HKLKLKQM-QKTIDNFSKVSDSNKEIVR--LTEELHHLSQKVAELEEEKGNLQLHLVDYD 589
             K++  Q  Q+T  + +++  +N  +    L ++    +++    +++    +L  +D  
Sbjct: 990  IKVQNDQNNQQTSSSQNELQQNNPGLSESSLKDQTIQQNEEFQVQKQQHDENKLDALDLL 1049

Query: 590  SGRMIESDVYKKMIEMENLAETRLKA-ISLLESQKFDLVQELHILQQKYDEVEDKLADIS 648
                 +++   K  + +   +T   A ++L E       Q   I +   +E+  K+ D S
Sbjct: 1050 MNNNTQTNQPSKKKKKKKKGKTNSNAPVNLFEEST---PQNEFINESSQNEL--KILD-S 1103

Query: 649  QLQSDQVCSEIKSVHLEEQIDALSASKKELA-------LVIENLKLD-------KEQLYG 694
             +QS++   + K   LE+Q D  S + K+           ++N   +       K+ +  
Sbjct: 1104 SMQSNKSNKDQKQ--LEKQQDEQSQNNKQAQKDNFYNQFEVKNENWENQFFNTAKQNIQD 1161

Query: 695  TIKDL-ENDKEDIMNKLQNY---IQENMDLT-DKLEKMSAEKISELLAKINHEEQSKIQT 749
              KD+ +N +++  +K QN         D + DK+   S +K +     +N  EQ++I+ 
Sbjct: 1162 AFKDISKNQQQNNASKNQNQQISFDSKADQSFDKVLNNSIDKNNLQKKNLNEREQTQIRN 1221

Query: 750  -QFGIDAKIQE--RDLYIENIES---ELSKYKSRI---CRLEESIAVMEDRRYSLERK-- 798
             Q  + + IQE  + L  +NIE    E   +  ++     +E+     E  + S++R   
Sbjct: 1222 NQEDLFSNIQENKQKLTFQNIEELNVEEDAWGIQVESPKEIEQQGKQNEVPKESIQRDNE 1281

Query: 799  -ADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQI 857
             A+      Q K ++ S + ++++  V ++  + +       Q  + + + K+ +++++I
Sbjct: 1282 HAEIKNDTFQSKLESQSFFQVEQNNNVQKIFEIQNDFFSQINQQNQQDKQQKDEKQESKI 1341

Query: 858  LLEENQNLQISLSDMQQHYN------------------ALVE-KANRTDLAESESTKYQT 898
               E QN+QI +SD+    N                  A++E K N +DL  S+  +   
Sbjct: 1342 NKNETQNVQILISDVDLDDNWGTSQPQNDSNDNNLKTQAIIESKLNNSDLKSSKHKEELD 1401

Query: 899  QL-RDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNI--- 954
            Q  +  E +LK   +  Q  I + K +I DL +  N Q ++    KK    K  KN+   
Sbjct: 1402 QSSKQDEFSLKEQKNAQQ--IQEHKLDILDLLMSNNNQ-QTGQTVKKKKKSKKAKNVNNQ 1458

Query: 955  ------EYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYI 1008
                  E   Q   Q +  +N+I+NL+ +++ + K N E   K    +  ++     Q +
Sbjct: 1459 SLNLFEENTPQSTQQNETSQNDIKNLDNSIQSI-KQNKEQ-KKQASSENIENNSDLNQQL 1516

Query: 1009 NEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVS 1068
            N   +  +L K  ++       K +N Q   ++     E+K+       +N + E+Q  +
Sbjct: 1517 NTSTQKGSLEKLNED-------KQDNCQKEQIAFEQS-ENKIIDIN---KNDQSEIQTDN 1565

Query: 1069 KQLLDSKQHNEELQILVRE---QDDQIKELKETKL-TFEMNIPKTEGMIISSTIEPMSDD 1124
            K+ L  +Q N+ +  +  E   Q+ Q + ++E K    E+N  + E   +   IE +  D
Sbjct: 1566 KEEL--QQENQRIHQIEEENVHQESQAENIQEIKFDNIEVNQTENEQKQLE-LIEEIQID 1622

Query: 1125 ANNVDXXXXXXXXXXXXLKVQEEEEFIQERS---VLQEQSAKLNTELQECYTKIIQLETL 1181
                             LK QE  + + E +   V QE   ++   + +    I Q    
Sbjct: 1623 IEINQQQQRQEEMQIKDLK-QENNQIVSEENQINVNQEIDTQVEQAINQENDDINQNSNN 1681

Query: 1182 NTELTGHDVVNQEQINQ-LKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWK 1240
              + T  +  N+EQ NQ +    +Q +TE  N+  T    +    +  DQ   +  E +K
Sbjct: 1682 QIQFTYQEQDNKEQNNQEINEANQQQDTEEGNIEQTALINQGLAENIEDQSQEQKQEEFK 1741

Query: 1241 QHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQ 1300
              L+Q +   Q+   E  +Q +    +++Q  D      +++  +  + E +  +Q+ L+
Sbjct: 1742 --LSQDDVQGQEDLGE-NLQDNQKVQEFKQSEDDETDDKKDQEIQQKSNENIEIIQDNLE 1798

Query: 1301 DKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYK 1360
            D++E  +  QE+  DV      L  E+ + ++                   +  +N S +
Sbjct: 1799 DQQEVNQINQEEELDVKQNQSNLDQELNEREIQ-NSEVQNHQDVQENQINQIEKKN-SNE 1856

Query: 1361 QMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEA-KVLELTH------QLELKD 1413
            Q++ QS L   + N   + S             ++   E  + ++L+       Q++L +
Sbjct: 1857 QLENQSELQAAQGNKHQEFSDEQNDNQDQINDDQILQQEQDEKIDLSQANNNDIQVDLNN 1916

Query: 1414 SEIYQKTHEYTITLTQRNDE---FENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENA 1470
                QK +     L +   E   FE+ +++ +  +K  E+L  +KE E   +  + +EN 
Sbjct: 1917 QIEDQKRNSLKENLVEDKQEEILFEDKQEENLVEDKEEENLVQDKEEENVEIIQQENENN 1976

Query: 1471 NHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQE 1530
             + E  Q++  + + +  +E N    E  +  +Q  +  + L+      NE+Q   + Q+
Sbjct: 1977 QNIE-QQQDQNVNQFENNQEQNT--FEDQNEQQQFKQEQEVLDNSEQIKNEIQQQ-QQQQ 2032

Query: 1531 IEIVTLNDEITNLQNMVRASSSK-IQKHVSFASDTK---QGRDEQLDNTMNKEL 1580
             E +  N +  N Q  +++   K ++  +    D K   Q  ++Q+D   ++++
Sbjct: 2033 TESIDSNQD--NQQLQIKSEEQKELEYELQNEDDQKIEEQQNNQQVDKAQSQQI 2084



 Score = 89.4 bits (212), Expect = 7e-16
 Identities = 160/801 (19%), Positives = 351/801 (43%), Gaps = 66/801 (8%)

Query: 307  KTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAV--SSPSK 364
            +T  ++K S +  N+    + + L E    Q  Q N+  +N +  +    +++  +   K
Sbjct: 1441 QTVKKKKKSKKAKNVNN--QSLNLFEENTPQSTQQNETSQNDIKNLDNSIQSIKQNKEQK 1498

Query: 365  KGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIA--KLEMVIQSLNKDLV 422
            K +   + ++  +   ++ +   + S E LN+D      K +IA  + E  I  +NK+  
Sbjct: 1499 KQASSENIENNSDLNQQLNTSTQKGSLEKLNEDKQDNCQKEQIAFEQSENKIIDINKNDQ 1558

Query: 423  DKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQ 482
             +    ++++            ++ +  + Q E+ Q ++  + I V     +  ++  ++
Sbjct: 1559 SEIQTDNKEELQQENQRIHQIEEENVHQESQAENIQEIKFDN-IEVNQTENEQKQLELIE 1617

Query: 483  E-QLKQELNDEIK---DVNVKDLIEKLKS--AEEQITQLNDEIDAANKNMIKVKSNHKLK 536
            E Q+  E+N + +   ++ +KDL ++     +EE    +N EID   +  I  +++    
Sbjct: 1618 EIQIDIEINQQQQRQEEMQIKDLKQENNQIVSEENQINVNQEIDTQVEQAINQENDD--- 1674

Query: 537  LKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNL-QLHLVDYDSGRMIE 595
            + Q       F+     NKE  +  +E++  +Q   + + E+GN+ Q  L++      IE
Sbjct: 1675 INQNSNNQIQFTYQEQDNKE--QNNQEINEANQ---QQDTEEGNIEQTALINQGLAENIE 1729

Query: 596  SDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKL-ADISQLQSDQ 654
                ++  E   L++  ++    L     D  +     Q + DE +DK   +I Q  ++ 
Sbjct: 1730 DQSQEQKQEEFKLSQDDVQGQEDLGENLQDNQKVQEFKQSEDDETDDKKDQEIQQKSNEN 1789

Query: 655  VCSEIKSVHLEEQIDALSASKKELALVIENLK-LDKEQLYGTIKDLE-NDKEDIMNKLQN 712
            +  EI   +LE+Q +    +++E   V +N   LD+E     I++ E  + +D+     N
Sbjct: 1790 I--EIIQDNLEDQQEVNQINQEEELDVKQNQSNLDQELNEREIQNSEVQNHQDVQENQIN 1847

Query: 713  YIQENMDLTDKLEKMSAEKISELLAKINH-EEQSKIQTQFGIDAKIQERDLYIENIESEL 771
             I E  +  ++LE  S  + ++        +EQ+  Q Q   D  +Q+     ++ + +L
Sbjct: 1848 QI-EKKNSNEQLENQSELQAAQGNKHQEFSDEQNDNQDQINDDQILQQE----QDEKIDL 1902

Query: 772  SKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLM 831
            S+  +   +++ +  + + +R SL+       + +++KQ+       QE+ LV       
Sbjct: 1903 SQANNNDIQVDLNNQIEDQKRNSLKE------NLVEDKQEEILFEDKQEENLVE------ 1950

Query: 832  DHDRVVEKQLLEIEHENKEL-QKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAE 890
              D+  E  + + E EN E+ Q++N    E NQN++         +    E+    D  E
Sbjct: 1951 --DKEEENLVQDKEEENVEIIQQEN----ENNQNIEQQQDQNVNQFENNQEQNTFEDQNE 2004

Query: 891  SESTKYQTQLRDLESNLK---RITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLN 947
             +  K + ++ D    +K   +   + QT  +   ++ + L+I+   Q E     +   +
Sbjct: 2005 QQQFKQEQEVLDNSEQIKNEIQQQQQQQTESIDSNQDNQQLQIKSEEQKELEYELQNEDD 2064

Query: 948  EKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQY 1007
            +K E+        +AQ Q+ ++  +N+N  +E+L +  +EL     Q  Q +S    E+ 
Sbjct: 2065 QKIEEQQNNQQVDKAQSQQIQHEEQNMNAQLEQLEENPVEL-----QTNQLESNGQNEEN 2119

Query: 1008 INEIN-KLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQR 1066
            I+  N +   L  QK++E   L+++    +    +  ++ E++  Q   K  N+++E   
Sbjct: 2120 IDHYNLETENLDNQKEKE---LHEEQTQEEKPIENQQNEDENQ--QLNQKENNIQKEDIE 2174

Query: 1067 VSKQLLDSKQHNEELQILVRE 1087
            ++ Q  + K    +   L+ E
Sbjct: 2175 ITSQTKEEKPKELDEDDLLNE 2195



 Score = 84.6 bits (200), Expect = 2e-14
 Identities = 138/758 (18%), Positives = 318/758 (41%), Gaps = 72/758 (9%)

Query: 860  EENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIV 919
            ++N+N    L DM    +  +  AN+ +  + ++ +Y+T +   +   ++ T++ + L  
Sbjct: 16   QQNENGFSDLLDMMNEVSKKLPTANKNNQVQEQTNQYKTDMTIQQQQQQQETNQQKWLFY 75

Query: 920  QKKKEIEDLEI-----------EFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQ---LQ 965
             K+K + D +I            F+   E      +    +    +++   L+ Q    Q
Sbjct: 76   NKQK-VADFDINEDDLNDGWGDNFSDPEEEEDNQNEGNGNQSNNQVDFSDLLKGQNPSRQ 134

Query: 966  EYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLN---ALLKQ-K 1021
            + ++  +      +EL+ +  E  +    + Q Q  +Y     N  + LN      +Q +
Sbjct: 135  QIQHANKGGQQKKDELDVVEEESNNCDESQIQNQIREYQNNSKNNYDSLNINDGFQQQFQ 194

Query: 1022 DEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEEL 1081
             +++    Q    A+ S      + E K+ +     E  E++     KQ    KQ N E 
Sbjct: 195  QKQVNEKMQGFGGAKQSQSQNAFNQEKKVQKDNLFQEQQEKKQNDQKKQ----KQKNIEF 250

Query: 1082 QI-LVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXX 1140
             +  VR+  +    L + KL F++++   +   I    E +      +D           
Sbjct: 251  SLEYVRQISEMQNLLNQEKLEFQLSLQARQNH-IQMWEEDLKLRQEALDRQLDEKNALDK 309

Query: 1141 XLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQ------- 1193
              K+Q ++  +++ +  Q+  A+L  E++E Y +++ L++   +L       Q       
Sbjct: 310  --KIQIKKAILKDEND-QQHEAQLK-EIKEKYRQLV-LKSKQQKLAFQKAFKQIDLKGKL 364

Query: 1194 -EQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQK 1252
             E   ++ S +EQ   E+    + +A+      S  +Q   EI +L +    +++   Q 
Sbjct: 365  NEMREEIHSMIEQEKEESIQNFNDLAQKLLKEKSLNNQFQKEIRKL-RSDNQEKDIKIQS 423

Query: 1253 -TEHELRV---QLSAFESKYEQLLDSVQSSTQE-ETNKIVTMEQVTSLQNKLQDKEEHLR 1307
              EH   V   Q   +E + +QL D + S T++ +  +  + ++ T L NK+++      
Sbjct: 424  INEHTSTVERNQKEFYEKQLKQLQDKINSQTKKYQDEQSKSKQEQTELANKVKE------ 477

Query: 1308 NLQEKYADVINQIEILRSEIEDEKVAFXX---XXXXXXXXXXXXXXDLRTENQSYKQMQE 1364
             LQ++    + +IE+ +SEIE++ +                     DL+T  +  +Q ++
Sbjct: 478  -LQKQIDQQVAEIELFKSEIEEKDLLMKTQEDTIESRNKEIEIKGKDLKTIQKKLQQKEQ 536

Query: 1365 QSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYT 1424
            ++    N  N Q+K++              + + +  +++     +++  ++ Q+  E  
Sbjct: 537  EN----NSLNQQIKEAQNSLQQKQEETQKNIENLQQTIIKEKKSFQIEKEKLSQQLQEQL 592

Query: 1425 ITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELA-ILRLKMHENANHYETMQKESEIE 1483
              +  +    + + Q + E + +++ +  E  ++    ++    E     E +QKE + E
Sbjct: 593  NNVENKTLTIQKLNQTVTELQNKLKQIQLESNNQSGNQIKQIRQEYEQKIEKIQKEQQ-E 651

Query: 1484 RVKLIEELNVK----ITES----VSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVT 1535
            ++ LI++ N+K    +T+      SL KQ     + L E++ K NE Q  +++ +  +  
Sbjct: 652  QINLIKQENLKAISLLTQKDQKIESLQKQFNLQQQKLAEQIKKQNENQQLIQSLQQNLKN 711

Query: 1536 ---LNDEITN-LQNMVRASSSKIQKHVSFASDTKQGRD 1569
                N++I N  Q++   ++ +++     ++  KQ +D
Sbjct: 712  QNKFNNQIVNEQQDLQETNNQQLEDEYFLSTQQKQSQD 749


>UniRef50_A0CFQ2 Cluster: Chromosome undetermined scaffold_177, whole
            genome shotgun sequence; n=6; Eukaryota|Rep: Chromosome
            undetermined scaffold_177, whole genome shotgun sequence
            - Paramecium tetraurelia
          Length = 2953

 Score =  126 bits (303), Expect = 7e-27
 Identities = 230/1144 (20%), Positives = 485/1144 (42%), Gaps = 102/1144 (8%)

Query: 476  NEIAKVQEQLKQELNDEI-KDVNVKDLIEKLKSAEE--QITQLNDEIDAANKNMIKVKSN 532
            +++ + +++L ++LN +I K ++ +  IE  +  E+  QI+ L  E     K +  V+  
Sbjct: 432  DQLIQTKQKLNEQLNQQIQKPLSSEKQIEFQQDPEKVFQISSLQAECVNLKKQIQDVEQQ 491

Query: 533  HKLKLKQMQKTID---NFSKVSD--SNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVD 587
             K  LK  +K +    N ++V    S+K+ +++         K  +L++E+  LQ  L+ 
Sbjct: 492  RKDDLKSFEKMLGEGVNETQVIGLTSDKQQLQIQVTGFEGQNKCDQLQQEQIALQNQLLQ 551

Query: 588  YDSGRMIESDVYKKMIEMENLAETRLKAISLLESQ---KFDLVQELHILQQKYDEVEDKL 644
             +  ++++     K  E E     +   I LLE Q     D  QEL  LQQ+       L
Sbjct: 552  KNK-QIVDLQDETKQSEKEEQIRGKDNEIKLLEQQVQTAKDQYQELLDLQQQ------NL 604

Query: 645  ADISQLQSDQVCSEIKSVHLEEQI--DALSASKKELALVIENLKLDKEQLYGTIKDLE-- 700
                Q   +++  + K +H +E++  +     + E+  +   L   +E+L    KD E  
Sbjct: 605  TPGGQ--KEKILQQTKEIHDQEEVINELQQKVETEVPQLQGQLSEAQEKLKDAQKDAELW 662

Query: 701  NDK-EDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQE 759
            N K  +++   Q  +Q N+   +++EK+S+E+    L ++N +   K Q    ++  +Q 
Sbjct: 663  NKKYHELLESKQTQVQ-NILAPEEIEKLSSEEAKNALTQLNKQYSDKAQENKELEMVVQH 721

Query: 760  RDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTI- 818
                 ++++S   K + +    ++  +V+E +   L  +   L +  + +    S++   
Sbjct: 722  LR---QDLDSSQEKVQQQAKEAQQEKSVLEQQTQLLNNQLKDLVAKEEVQPTRESQWLTF 778

Query: 819  --QEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHY 876
              ++ + ++     +   +  + Q  ++  + +E++ K +IL EE + L+I L       
Sbjct: 779  WKKQYQQLSEKQPEISSTQAGDLQEQQVSQQEREVKPK-EILNEEVELLKIKL------- 830

Query: 877  NALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQI 936
                EK N       E    Q  ++D     K+  +E     +QK +   D +I+F T  
Sbjct: 831  ----EKLNDMQKENEELKAQQILIQDELLKTKQQLNEQLQQQIQKPQG-NDQQIQFQTDP 885

Query: 937  ESAIRDKKVLNE--KYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQ 994
            E  ++   +  E    +K I+ V Q   +  + K+  + L   V E   + L    + +Q
Sbjct: 886  EKVLQISSLQAECVNLKKQIQDVEQ--QRKDDLKSFEKMLGEGVNETQVIGLTSDKQQLQ 943

Query: 995  KQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLA-QF 1053
                Q  +  +Q   E   L   L QK+++I+ L  +   ++        D E KL  Q 
Sbjct: 944  SDLRQLQNKCDQLQQEQIALQDQLLQKNKQIVDLQDETKQSEKEEQIRGKDNEIKLLEQQ 1003

Query: 1054 TTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMI 1113
                ++  +E+  + +Q L      E++    +E  DQ + + + +   E  +P+ + ++
Sbjct: 1004 VQTAKDQYQELLDLQQQNLTPGGQKEKILQQTKEIHDQEEVINQLQHKVETEVPQLQNLL 1063

Query: 1114 ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYT 1173
              +  E   +  N  D              +QE ++ + +  V  EQ    N +L +   
Sbjct: 1064 CEAE-EKAKEAQNQADLWNKKYKD------LQEAKQQLVDDYVKPEQIE--NYDLDQAKD 1114

Query: 1174 KIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGF 1233
                L  LN EL     +N EQ+        Q+N    N L    ++ S   + +D    
Sbjct: 1115 A---LNKLNEELKKQKQINNEQL--------QINENLKNQLKDPQQMLSQAQNEIDDLKL 1163

Query: 1234 EIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVT 1293
            +  +L K  L Q +   Q+   +L+ Q+   +   +Q    +Q  T  E  K++   Q++
Sbjct: 1164 DQIKL-KDELIQAK---QQLNEQLQQQIQKPQGNDQQ----IQFQTDPE--KVL---QIS 1210

Query: 1294 SLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLR 1353
            SLQ +  + ++ +++++++  D +   E +  E  +E                    DLR
Sbjct: 1211 SLQAQCVNLKKQIQDVEQQRKDDLKSFEKMLGEGVNETQVIGLTSDKQQLQS-----DLR 1265

Query: 1354 TENQSYKQMQEQSILN---INEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLE 1410
                   Q+Q++ I     + ++N Q+                R  D E K+LE   Q  
Sbjct: 1266 QLQNKCDQLQQEQIAQQDQLLQKNKQIVDLQDETKQSEKEEQIRGKDNEIKLLEQQVQTA 1325

Query: 1411 LKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENA 1470
                +      +  +T   + ++     +++ + E+ I +L  + E+E+  L+ ++ E  
Sbjct: 1326 KDQYQELLDLQQQNLTPGGQKEKILQQTKEIHDQEEVINELQQKVETEVPQLQGQLSEAQ 1385

Query: 1471 NHYETMQKESEIERVKLIEELNVKIT--ESVSLNKQVAEL-NKALEEEVAKTNEMQT--A 1525
               +  QK++E+   K  E L  K T  +++   +++ +L ++  +  + + N+  +  A
Sbjct: 1386 EKLKDAQKDAELWNKKYHELLESKQTQVQNILAPEEIEKLSSEEAKNALTQLNKQYSDKA 1445

Query: 1526 LENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVP 1585
             EN+E+E+V     + +L+  + +S  K+Q+    A   K   ++Q    +N +L D V 
Sbjct: 1446 QENKELEMV-----VQHLRQDLDSSQEKVQQQAKEAQQEKSVLEQQ-TQLLNNQLKDLVA 1499

Query: 1586 RAEL 1589
            + E+
Sbjct: 1500 KEEV 1503



 Score =  118 bits (283), Expect = 2e-24
 Identities = 230/1242 (18%), Positives = 538/1242 (43%), Gaps = 115/1242 (9%)

Query: 399  DKKIN-KNEIAK--LEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLE 455
            +KKIN KN I K  L+ V Q   +DL   + +I                +     Q QL 
Sbjct: 3    NKKINQKNIILKDQLQEVEQQRQEDLKSFKEIIGNGADQQCIADLVTQKQKLQTDQRQLL 62

Query: 456  HQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQL 515
             Q +     LI       + NE+ K+  QLK +  D+I+   +++  E LK  + +I  L
Sbjct: 63   IQINKLQEELIQ---QQNENNEMKKMVNQLKNQQQDQIQ---IQE-NEVLKIRQNEIDDL 115

Query: 516  N-DEIDAANKNM-IKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAE 573
              D+I   ++ +  K K N +L  +Q+QK +        S+++ +   ++   + Q ++ 
Sbjct: 116  KLDQIKLKDELIQTKQKLNEQLN-QQIQKPL--------SSEKQIEFQQDPEKVFQ-ISS 165

Query: 574  LEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHIL 633
            L+ E  NL+  + D +  R  +   ++KM+  E + ET++     L S K  L  +L  L
Sbjct: 166  LQAECVNLKKQIQDVEQQRKDDLKSFEKMLG-EGVNETQVIG---LTSDKQQLQSDLRQL 221

Query: 634  QQKYDEV-EDKLADISQL--QSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKE 690
            Q K D++ ++++A   QL  ++ Q+          E+ + +     E+ L+ + ++  K+
Sbjct: 222  QNKCDQLQQEQIALQDQLLQKNKQIVDLQDETKQSEKEEQIRGKDNEIKLLEQQVQTAKD 281

Query: 691  QLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQ 750
            Q Y  + DL+        + +  +Q+  ++ D+          E++ ++ H+ ++++   
Sbjct: 282  Q-YQELLDLQQQNLTPGGQKEKILQQTKEIHDQ---------EEVINQLQHKVETEVPQL 331

Query: 751  FGIDAKIQERDLYIENIESEL--SKYK----SRICRLEESIAVMEDRRYSLERKADQLGS 804
              +  + +E+    +N +++L   KYK    ++   +++ +   +   Y L++  D L  
Sbjct: 332  QNLLCEAEEKAKEAQN-QADLWNKKYKDLQEAKQQLVDDYVKPEQIENYDLDQAKDALNK 390

Query: 805  YLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQN 864
             + E+ K   +   ++ ++ NR  +    + + + +L +I+ +++ +Q K ++  + NQ 
Sbjct: 391  -MNEELKKQKQINNEQLQIHNR-CLHETQNEIDDLKLDQIKLKDQLIQTKQKLNEQLNQQ 448

Query: 865  LQISLSDMQQ-HYNALVEKANRTDLAESESTKYQTQLRDLESNLK-------RITHE--H 914
            +Q  LS  +Q  +    EK  +    ++E    + Q++D+E   K       ++  E  +
Sbjct: 449  IQKPLSSEKQIEFQQDPEKVFQISSLQAECVNLKKQIQDVEQQRKDDLKSFEKMLGEGVN 508

Query: 915  QTLIVQKKKEIEDLEIE---FNTQIE-SAIRDKKVL--NEKYEKNIEYV--------TQL 960
            +T ++    + + L+I+   F  Q +   ++ +++   N+  +KN + V        ++ 
Sbjct: 509  ETQVIGLTSDKQQLQIQVTGFEGQNKCDQLQQEQIALQNQLLQKNKQIVDLQDETKQSEK 568

Query: 961  EAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQK-----------QQTQSPDYTEQYIN 1009
            E Q++   N I+ L   V+       EL+D   Q            QQT+     E+ IN
Sbjct: 569  EEQIRGKDNEIKLLEQQVQTAKDQYQELLDLQQQNLTPGGQKEKILQQTKEIHDQEEVIN 628

Query: 1010 EI-NKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENM--EEEMQR 1066
            E+  K+   + Q   ++    +K+ +AQ         Y   L    T+++N+   EE+++
Sbjct: 629  ELQQKVETEVPQLQGQLSEAQEKLKDAQKDAELWNKKYHELLESKQTQVQNILAPEEIEK 688

Query: 1067 VS------------KQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMII 1114
            +S            KQ  D  Q N+EL+++V+     +   +E K+  +    + E  ++
Sbjct: 689  LSSEEAKNALTQLNKQYSDKAQENKELEMVVQHLRQDLDSSQE-KVQQQAKEAQQEKSVL 747

Query: 1115 SSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTK 1174
                + +++   ++                  ++++ Q      E S+    +LQE    
Sbjct: 748  EQQTQLLNNQLKDLVAKEEVQPTRESQWLTFWKKQYQQLSEKQPEISSTQAGDLQE---- 803

Query: 1175 IIQLETLNTELTGHDVVNQEQINQLKSKLEQLN---TENDNLLSTVAELRSSISSAVDQR 1231
              Q+     E+   +++N E++  LK KLE+LN    EN+ L +    ++  +     Q 
Sbjct: 804  -QQVSQQEREVKPKEILN-EEVELLKIKLEKLNDMQKENEELKAQQILIQDELLKTKQQL 861

Query: 1232 GFEI-AELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTME 1290
              ++  ++ K     ++  FQ T+ E  +Q+S+ +++   L   +Q   Q+  + + + E
Sbjct: 862  NEQLQQQIQKPQGNDQQIQFQ-TDPEKVLQISSLQAECVNLKKQIQDVEQQRKDDLKSFE 920

Query: 1291 QVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXX 1350
            ++   +   + +   L + +++    + Q++    +++ E++A                 
Sbjct: 921  KMLG-EGVNETQVIGLTSDKQQLQSDLRQLQNKCDQLQQEQIALQDQLLQKNKQIVDLQD 979

Query: 1351 DLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLE 1410
            + +   +  +   + + + + E+  Q  K                   + K+L+ T ++ 
Sbjct: 980  ETKQSEKEEQIRGKDNEIKLLEQQVQTAKDQYQELLDLQQQNLTPGGQKEKILQQTKEIH 1039

Query: 1411 LKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENA 1470
             ++  I Q  H+    + Q  +      ++  E + +  DL  +K  +L   + ++ ++ 
Sbjct: 1040 DQEEVINQLQHKVETEVPQLQNLLCEAEEKAKEAQNQ-ADLWNKKYKDLQEAKQQLVDDY 1098

Query: 1471 NHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQE 1530
               E ++     +    + +LN ++ +   +N +  ++N+ L+ ++    +M +  +N E
Sbjct: 1099 VKPEQIENYDLDQAKDALNKLNEELKKQKQINNEQLQINENLKNQLKDPQQMLSQAQN-E 1157

Query: 1531 IEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQL 1572
            I+ + L D+I     +++A   ++ + +       QG D+Q+
Sbjct: 1158 IDDLKL-DQIKLKDELIQA-KQQLNEQLQQQIQKPQGNDQQI 1197



 Score =  116 bits (280), Expect = 4e-24
 Identities = 270/1464 (18%), Positives = 613/1464 (41%), Gaps = 116/1464 (7%)

Query: 143  DVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQE--KINEKDQIIEAKNKATTXXXXXX 200
            D+  L N   +       LQ ++      I+DLQ+  K +EK++ I  K+          
Sbjct: 217  DLRQLQNKCDQLQQEQIALQDQLLQKNKQIVDLQDETKQSEKEEQIRGKDNEIKLLEQQV 276

Query: 201  XXXXXXXXXXXEDTKQQMTK--MQENFIAMEAEWKDEKQ---RLLKDIESKDVRISSLE- 254
                       +  +Q +T    +E  +    E  D+++   +L   +E++  ++ +L  
Sbjct: 277  QTAKDQYQELLDLQQQNLTPGGQKEKILQQTKEIHDQEEVINQLQHKVETEVPQLQNLLC 336

Query: 255  EANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKG 314
            EA +  + A+ +  L + K  ++L++              +    ++ + +   ++ E  
Sbjct: 337  EAEEKAKEAQNQADLWNKKY-KDLQEAKQQLVDDYVKPEQIENYDLDQAKDALNKMNE-- 393

Query: 315  SLEIANMTELTKKIELLEHLNCQIRQTNKELEN-KLATMGTESKAVSSPSKKGSPLISRK 373
              E+    ++  + +L  H  C + +T  E+++ KL  +  + + + +  K    L    
Sbjct: 394  --ELKKQKQINNE-QLQIHNRC-LHETQNEIDDLKLDQIKLKDQLIQTKQKLNEQL---- 445

Query: 374  SGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDT 433
                   +++ P S        QD +K     +I+ L+    +L K + D E     KD 
Sbjct: 446  -----NQQIQKPLSSEKQIEFQQDPEKVF---QISSLQAECVNLKKQIQDVEQ--QRKDD 495

Query: 434  XXXXXXXXXXG-KDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDE 492
                      G  +T +  L  + QQ       I V T  E  N+  ++Q++     N  
Sbjct: 496  LKSFEKMLGEGVNETQVIGLTSDKQQLQ-----IQV-TGFEGQNKCDQLQQEQIALQNQL 549

Query: 493  I-KDVNVKDLIEKLKSAE--EQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTID---N 546
            + K+  + DL ++ K +E  EQI   ++EI    + +   K  ++  L   Q+ +     
Sbjct: 550  LQKNKQIVDLQDETKQSEKEEQIRGKDNEIKLLEQQVQTAKDQYQELLDLQQQNLTPGGQ 609

Query: 547  FSKVSDSNKEIVRLTEELHHLSQKV-AELEEEKGNL---QLHLVDYDSGRMIESDVYKKM 602
              K+    KEI    E ++ L QKV  E+ + +G L   Q  L D      + +  Y ++
Sbjct: 610  KEKILQQTKEIHDQEEVINELQQKVETEVPQLQGQLSEAQEKLKDAQKDAELWNKKYHEL 669

Query: 603  IEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQS--DQVCSEIK 660
            +E +      + A    E +K    +  + L Q   +  DK  +  +L+     +  ++ 
Sbjct: 670  LESKQTQVQNILAPE--EIEKLSSEEAKNALTQLNKQYSDKAQENKELEMVVQHLRQDLD 727

Query: 661  SVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDL 720
            S   + Q  A  A ++E +++ +  +L   QL   +   E         L  + ++   L
Sbjct: 728  SSQEKVQQQAKEA-QQEKSVLEQQTQLLNNQLKDLVAKEEVQPTRESQWLTFWKKQYQQL 786

Query: 721  TDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICR 780
            ++K  ++S+ +  +L  +   +++ +++ +  ++ +++   + +E + +++ K    +  
Sbjct: 787  SEKQPEISSTQAGDLQEQQVSQQEREVKPKEILNEEVELLKIKLEKL-NDMQKENEEL-- 843

Query: 781  LEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQED-ELVNRLAVLMDHDRVVEK 839
              + I + ++   + ++  +QL   +Q+ Q    +   Q D E V +++ L      ++K
Sbjct: 844  KAQQILIQDELLKTKQQLNEQLQQQIQKPQGNDQQIQFQTDPEKVLQISSLQAECVNLKK 903

Query: 840  QLLEIEHENKELQKKNQILLEE--NQNLQISL-SDMQQHYNALVEKANRTDLAESESTKY 896
            Q+ ++E + K+  K  + +L E  N+   I L SD QQ  + L +  N+ D  + E    
Sbjct: 904  QIQDVEQQRKDDLKSFEKMLGEGVNETQVIGLTSDKQQLQSDLRQLQNKCDQLQQEQIAL 963

Query: 897  QTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEY 956
            Q QL  L+ N + +  + +T   +K+++I   + E    +E  ++  K   ++Y++ ++ 
Sbjct: 964  QDQL--LQKNKQIVDLQDETKQSEKEEQIRGKDNEIKL-LEQQVQTAK---DQYQELLD- 1016

Query: 957  VTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNA 1016
               L+ Q        E +    +E++    E+I++   K +T+ P    Q  N + +   
Sbjct: 1017 ---LQQQNLTPGGQKEKILQQTKEIHDQE-EVINQLQHKVETEVP----QLQNLLCEAEE 1068

Query: 1017 LLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQ 1076
              K+   +    N+K  + Q +   +V DY          L+  ++ + +++++L   KQ
Sbjct: 1069 KAKEAQNQADLWNKKYKDLQEAKQQLVDDYVKPEQIENYDLDQAKDALNKLNEELKKQKQ 1128

Query: 1077 -HNEELQILVREQDDQIKELKE--TKLTFEMNIPKTEGMIISSTIEPMSDDANN-VDXXX 1132
             +NE+LQI      +Q+K+ ++  ++   E++  K + + +   +       N  +    
Sbjct: 1129 INNEQLQIN-ENLKNQLKDPQQMLSQAQNEIDDLKLDQIKLKDELIQAKQQLNEQLQQQI 1187

Query: 1133 XXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVN 1192
                     ++ Q + E + + S LQ Q   L  ++Q+   +         ++ G  V N
Sbjct: 1188 QKPQGNDQQIQFQTDPEKVLQISSLQAQCVNLKKQIQDVEQQRKDDLKSFEKMLGEGV-N 1246

Query: 1193 QEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQ---RGFEIAELWKQ-HLAQREA 1248
            + Q+  L S  +QL ++   L +   +L+    +  DQ   +  +I +L  +   +++E 
Sbjct: 1247 ETQVIGLTSDKQQLQSDLRQLQNKCDQLQQEQIAQQDQLLQKNKQIVDLQDETKQSEKEE 1306

Query: 1249 DFQKTEHELRV---QLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEH 1305
              +  ++E+++   Q+   + +Y++LLD  Q +      K    E++     ++ D+EE 
Sbjct: 1307 QIRGKDNEIKLLEQQVQTAKDQYQELLDLQQQNLTPGGQK----EKILQQTKEIHDQEEV 1362

Query: 1306 LRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQ 1365
            +  LQ+K    + Q++   SE +++                      +T+ Q+    +E 
Sbjct: 1363 INELQQKVETEVPQLQGQLSEAQEKLKDAQKDAELWNKKYHELLESKQTQVQNILAPEEI 1422

Query: 1366 SILNINE-ENA--QLKKSSXXXXXXXXXXXXRV-------NDAEAKVLELTHQLELKDSE 1415
              L+  E +NA  QL K               V       + ++ KV +   + + + S 
Sbjct: 1423 EKLSSEEAKNALTQLNKQYSDKAQENKELEMVVQHLRQDLDSSQEKVQQQAKEAQQEKSV 1482

Query: 1416 IYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIE----DLTYEKESELAILRLKMHE--- 1468
            + Q+T      L     + E  RQ++++ + +++    D   ++  +L+  + ++     
Sbjct: 1483 LEQQTQLLNNQLKDLVAKEEVQRQEILDLKNKLDQENADFWKKQYQQLSEKQPEISSTQA 1542

Query: 1469 -NANHYETMQKESEIERVKLIEE----LNVKITESVSLNKQVAELNKA---LEEEVAKTN 1520
             +    +  Q+E E++  +++ E    L +K+ +   + K+  EL      +++E+ KT 
Sbjct: 1543 GDLQEQQVSQQEREVKPKEILNEEVELLKIKLEKLNDMQKENEELKAQQILIQDELLKTK 1602

Query: 1521 EMQTALENQEIEIVTLNDEITNLQ 1544
            +       Q+I+    ND+    Q
Sbjct: 1603 QQLNEQLQQQIQKPQGNDQQIQFQ 1626



 Score = 92.7 bits (220), Expect = 8e-17
 Identities = 202/1110 (18%), Positives = 479/1110 (43%), Gaps = 97/1110 (8%)

Query: 525  NMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLH 584
            N  K+   + +   Q+Q+      +   S KEI+    +     Q +A+L  +K  LQ  
Sbjct: 2    NNKKINQKNIILKDQLQEVEQQRQEDLKSFKEIIGNGAD----QQCIADLVTQKQKLQ-- 55

Query: 585  LVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQ--ELHILQQKYDEVED 642
              D     +  + + +++I+ +N      K ++ L++Q+ D +Q  E  +L+ + +E++D
Sbjct: 56   -TDQRQLLIQINKLQEELIQQQNENNEMKKMVNQLKNQQQDQIQIQENEVLKIRQNEIDD 114

Query: 643  KLADISQLQSDQVCSEIK-SVHLEEQIDALSASKKEL--------ALVIENLKLDKEQLY 693
               D  +L+ + + ++ K +  L +QI    +S+K++           I +L+ +   L 
Sbjct: 115  LKLDQIKLKDELIQTKQKLNEQLNQQIQKPLSSEKQIEFQQDPEKVFQISSLQAECVNLK 174

Query: 694  GTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMS-AEKISELLAKINHEEQSKIQTQFG 752
              I+D+E  ++D +   +  + E ++ T  +   S  +++   L ++ ++     Q Q  
Sbjct: 175  KQIQDVEQQRKDDLKSFEKMLGEGVNETQVIGLTSDKQQLQSDLRQLQNKCDQLQQEQIA 234

Query: 753  IDAKIQERDLYIENIESEL--SKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQE-- 808
            +  ++ +++  I +++ E   S+ + +I   +  I ++E +  + + +  +L    Q+  
Sbjct: 235  LQDQLLQKNKQIVDLQDETKQSEKEEQIRGKDNEIKLLEQQVQTAKDQYQELLDLQQQNL 294

Query: 809  -----KQKAYSEYTI--QEDELVNRLAVLMDHD-RVVEKQLLEIEHENKELQKKNQILLE 860
                 K+K   +      ++E++N+L   ++ +   ++  L E E + KE Q +  +  +
Sbjct: 295  TPGGQKEKILQQTKEIHDQEEVINQLQHKVETEVPQLQNLLCEAEEKAKEAQNQADLWNK 354

Query: 861  ENQNLQISLSDMQQHYNALVEKANRT-DLAESESTKYQTQLRDLESNLKRITHEHQTLIV 919
            + ++LQ +   +   Y    +  N   D A+    K   +L+  +         H   + 
Sbjct: 355  KYKDLQEAKQQLVDDYVKPEQIENYDLDQAKDALNKMNEELKKQKQINNEQLQIHNRCLH 414

Query: 920  QKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVE 979
            + + EI+DL+++     +  I+ K+ LNE+  + I+     E Q+ E++ + E     V 
Sbjct: 415  ETQNEIDDLKLDQIKLKDQLIQTKQKLNEQLNQQIQKPLSSEKQI-EFQQDPE----KVF 469

Query: 980  ELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSY 1039
            +++ +  E ++    K+Q Q  D  +Q  +++     +L +   E   +    +  Q+  
Sbjct: 470  QISSLQAECVN---LKKQIQ--DVEQQRKDDLKSFEKMLGEGVNETQVIGLTSDKQQLQI 524

Query: 1040 MSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLD----SKQHNEELQILVREQDDQIKEL 1095
                 + ++K  Q   +   ++ ++ + +KQ++D    +KQ  +E QI  R +D++IK L
Sbjct: 525  QVTGFEGQNKCDQLQQEQIALQNQLLQKNKQIVDLQDETKQSEKEEQI--RGKDNEIKLL 582

Query: 1096 KETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQE-R 1154
            ++     ++   K +        E +     N+              ++ ++EE I E +
Sbjct: 583  EQ-----QVQTAKDQYQ------ELLDLQQQNLTPGGQKEKILQQTKEIHDQEEVINELQ 631

Query: 1155 SVLQEQSAKLNTELQECYTKIIQLETLNTELTG---HDVV--NQEQINQLKSKLEQLNTE 1209
              ++ +  +L  +L E   K+   +  + EL     H+++   Q Q+  + +  E     
Sbjct: 632  QKVETEVPQLQGQLSEAQEKLKDAQK-DAELWNKKYHELLESKQTQVQNILAPEEIEKLS 690

Query: 1210 NDNLLSTVAELRSSIS-SAVDQRGFE-IAELWKQHLAQREADFQKTEHELRVQLSAFESK 1267
            ++   + + +L    S  A + +  E + +  +Q L   +   Q+   E + + S  E +
Sbjct: 691  SEEAKNALTQLNKQYSDKAQENKELEMVVQHLRQDLDSSQEKVQQQAKEAQQEKSVLEQQ 750

Query: 1268 YEQLLDSVQS-STQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSE 1326
             + L + ++    +EE       + +T  + + Q   E    +    A  + + ++ + E
Sbjct: 751  TQLLNNQLKDLVAKEEVQPTRESQWLTFWKKQYQQLSEKQPEISSTQAGDLQEQQVSQQE 810

Query: 1327 IEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQ---EQSILNINEE-NAQLKKSSX 1382
             E +                    D++ EN+  K  Q   +  +L   ++ N QL++   
Sbjct: 811  REVKPKEILNEEVELLKIKLEKLNDMQKENEELKAQQILIQDELLKTKQQLNEQLQQQIQ 870

Query: 1383 XXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLV 1442
                       +  D E KVL+++  L+ +   + ++  +      QR D+ ++  + L 
Sbjct: 871  KPQGNDQQIQFQ-TDPE-KVLQIS-SLQAECVNLKKQIQDVE---QQRKDDLKSFEKMLG 924

Query: 1443 E--YEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVS 1500
            E   E ++  LT +K+     L+  + +  N  + +Q+    E++ L ++L  K  + V 
Sbjct: 925  EGVNETQVIGLTSDKQQ----LQSDLRQLQNKCDQLQQ----EQIALQDQLLQKNKQIVD 976

Query: 1501 LNKQVAELNKALEEEV-AKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVS 1559
            L  +  +  K  EE++  K NE++  LE Q   + T  D+   L ++ + + +   +   
Sbjct: 977  LQDETKQSEK--EEQIRGKDNEIK-LLEQQ---VQTAKDQYQELLDLQQQNLTPGGQKEK 1030

Query: 1560 FASDTKQGRD-EQLDNTMNKELLDAVPRAE 1588
                TK+  D E++ N +  ++   VP+ +
Sbjct: 1031 ILQQTKEIHDQEEVINQLQHKVETEVPQLQ 1060



 Score = 85.0 bits (201), Expect = 2e-14
 Identities = 138/748 (18%), Positives = 321/748 (42%), Gaps = 43/748 (5%)

Query: 858  LLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTL 917
            L+ + Q LQ     +    N L E+  +     +E  K   QL++ + +  +I  E++ L
Sbjct: 47   LVTQKQKLQTDQRQLLIQINKLQEELIQQQNENNEMKKMVNQLKNQQQDQIQI-QENEVL 105

Query: 918  IVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMN 977
             + ++ EI+DL+++     +  I+ K+ LNE+  + I+     E Q++  ++  +   ++
Sbjct: 106  KI-RQNEIDDLKLDQIKLKDELIQTKQKLNEQLNQQIQKPLSSEKQIEFQQDPEKVFQIS 164

Query: 978  VEELNKMNLELIDKHVQKQQTQSPDYTEQYINE-INKLNALLKQKDEEIIA--LNQKINN 1034
              +   +NL+   + V++Q+       E+ + E +N+   +    D++ +   L Q  N 
Sbjct: 165  SLQAECVNLKKQIQDVEQQRKDDLKSFEKMLGEGVNETQVIGLTSDKQQLQSDLRQLQNK 224

Query: 1035 AQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEE--LQILVREQDDQI 1092
                    ++  + +L Q   ++ ++++E ++  K+     + NE   L+  V+   DQ 
Sbjct: 225  CDQLQQEQIA-LQDQLLQKNKQIVDLQDETKQSEKEEQIRGKDNEIKLLEQQVQTAKDQY 283

Query: 1093 KELKETKLTFEMNI-PKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLK--VQEEEE 1149
            +EL + +   + N+ P  +   I    + + D    ++            L+  + E EE
Sbjct: 284  QELLDLQ---QQNLTPGGQKEKILQQTKEIHDQEEVINQLQHKVETEVPQLQNLLCEAEE 340

Query: 1150 FIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVN-QEQINQLKSKLEQLNT 1208
              +E     +   K   +LQE   +++       ++  +D+   ++ +N++  +L++   
Sbjct: 341  KAKEAQNQADLWNKKYKDLQEAKQQLVDDYVKPEQIENYDLDQAKDALNKMNEELKKQKQ 400

Query: 1209 ENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKY 1268
             N+  L           + +D    +  +L K  L Q +   QK   +L  Q+       
Sbjct: 401  INNEQLQIHNRCLHETQNEIDDLKLDQIKL-KDQLIQTK---QKLNEQLNQQIQ------ 450

Query: 1269 EQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIE 1328
            + L    Q   Q++  K+    Q++SLQ +  + ++ +++++++  D +   E +  E  
Sbjct: 451  KPLSSEKQIEFQQDPEKVF---QISSLQAECVNLKKQIQDVEQQRKDDLKSFEKMLGEGV 507

Query: 1329 DEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILN--INEENAQLKKSSXXXXX 1386
            +E                    +   +N+  +  QEQ  L   + ++N Q+         
Sbjct: 508  NETQVIGLTSDKQQLQIQVTGFE--GQNKCDQLQQEQIALQNQLLQKNKQIVDLQDETKQ 565

Query: 1387 XXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEK 1446
                   R  D E K+LE   Q      +      +  +T   + ++     +++ + E+
Sbjct: 566  SEKEEQIRGKDNEIKLLEQQVQTAKDQYQELLDLQQQNLTPGGQKEKILQQTKEIHDQEE 625

Query: 1447 RIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKIT--ESVSLNKQ 1504
             I +L  + E+E+  L+ ++ E     +  QK++E+   K  E L  K T  +++   ++
Sbjct: 626  VINELQQKVETEVPQLQGQLSEAQEKLKDAQKDAELWNKKYHELLESKQTQVQNILAPEE 685

Query: 1505 VAEL-NKALEEEVAKTNEMQT--ALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFA 1561
            + +L ++  +  + + N+  +  A EN+E+E+V     + +L+  + +S  K+Q+    A
Sbjct: 686  IEKLSSEEAKNALTQLNKQYSDKAQENKELEMV-----VQHLRQDLDSSQEKVQQQAKEA 740

Query: 1562 SDTKQGRDEQLDNTMNKELLDAVPRAEL 1589
               K   ++Q    +N +L D V + E+
Sbjct: 741  QQEKSVLEQQ-TQLLNNQLKDLVAKEEV 767



 Score = 76.2 bits (179), Expect = 7e-12
 Identities = 112/524 (21%), Positives = 240/524 (45%), Gaps = 42/524 (8%)

Query: 596  SDVYKKMIEMENLAET-RLKAISLLESQKFDLVQEL---HILQQKYDEVEDKLADISQLQ 651
            S+  +K+ + +  AE    K   LLES++  +   L    I +   +E ++ L  +++  
Sbjct: 2353 SEAQEKLKDAQKDAELWNKKYHELLESKQTQVQNILAPEEIEKLSSEEAKNALTQLNKQY 2412

Query: 652  SD--QVCSEIKSV--HLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIM 707
            SD  Q   E++ V  HL + +D+   S++++    +  + +K  L    + L N  +D++
Sbjct: 2413 SDKAQENKELEMVVQHLRQDLDS---SQEKVQQQAKEAQQEKSVLEQQTQLLNNQLKDLV 2469

Query: 708  NKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFG--IDAKIQERDLYIE 765
             K +   QE +DL +KL++ +A+   +   +++ ++     TQ G   + ++ +++  ++
Sbjct: 2470 AKEEVQRQEILDLKNKLDQENADFWKKQYQQLSEKQPEISSTQAGDLQEQQVSQQEREVK 2529

Query: 766  NIESELSKYKSRICRLEESIAVMEDRRYSLE--------RKADQLGSYLQEKQKAYSEYT 817
              E    +    IC+  + +   +  RY  +         + ++L   +Q+ Q    +  
Sbjct: 2530 PKEILNEERNQMICK--KKMKNWKHNRYQFKMNYSKLSNSQMNKLQQQIQKPQGNDQQIQ 2587

Query: 818  IQED-ELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEE--NQNLQISL-SDMQ 873
             Q D E V +++ L      ++KQ+ ++E + K+  K  + +L E  N+   I L SD Q
Sbjct: 2588 FQTDPEKVLQISSLQAECVNLKKQIQDVEQQRKDDLKSFEKMLGEGVNETQVIGLTSDKQ 2647

Query: 874  QHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFN 933
            Q  + L +  N+ D  + E    Q QL  L+ N + +  + +T   +K+++I   + E  
Sbjct: 2648 QLQSDLRQLQNKCDQLQQEQIALQNQL--LQKNKQIVDLQDETKQSEKEEQIRGKDNEIK 2705

Query: 934  TQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHV 993
              +E  ++  K   ++Y++ ++    L+ Q        E +    +E++    E+I++  
Sbjct: 2706 L-LEQQVQTAK---DQYQELLD----LQQQNLTPGGQKEKILQQTKEIHDQE-EVINELQ 2756

Query: 994  QKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQF 1053
            QK +T+ P    Q      KL     QKD E+   N+K +    S  + V +  +     
Sbjct: 2757 QKVETEVPQLQGQLSEAQEKLKD--AQKDAEL--WNKKYHELLESKQTQVQNILAPEEIE 2812

Query: 1054 TTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKE 1097
                E  +  + +++KQ  D  Q N+EL+++V+     +   +E
Sbjct: 2813 KLSSEEAKNALTQLNKQYSDKAQENKELEMVVQHLRQDLDSSQE 2856



 Score = 74.9 bits (176), Expect = 2e-11
 Identities = 137/632 (21%), Positives = 277/632 (43%), Gaps = 62/632 (9%)

Query: 476  NEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKL 535
            N     + +L  EL  ++ +  V  L  +L  A+E++     + +  NK   ++  + + 
Sbjct: 2324 NTTETFRHKLINELQQKV-ETEVPQLQGQLSEAQEKLKDAQKDAELWNKKYHELLESKQT 2382

Query: 536  KLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIE 595
            +++ +    +   K+S    +   LT+     S K  E +E +  +Q    D DS +   
Sbjct: 2383 QVQNILAP-EEIEKLSSEEAKNA-LTQLNKQYSDKAQENKELEMVVQHLRQDLDSSQEKV 2440

Query: 596  SDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQV 655
                K+  + +++ E + +   LL +Q  DLV +  + +Q+  ++++KL    Q  +D  
Sbjct: 2441 QQQAKEAQQEKSVLEQQTQ---LLNNQLKDLVAKEEVQRQEILDLKNKL---DQENADFW 2494

Query: 656  CSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIM---NKLQN 712
              + + +  E+Q +  S    +L    +  ++ +++     K++ N++ + M    K++N
Sbjct: 2495 KKQYQQLS-EKQPEISSTQAGDL----QEQQVSQQEREVKPKEILNEERNQMICKKKMKN 2549

Query: 713  YIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELS 772
            +            K+S  ++++L  +I   + +  Q QF  D    E+ L I ++++E  
Sbjct: 2550 WKHNRYQFKMNYSKLSNSQMNKLQQQIQKPQGNDQQIQFQTDP---EKVLQISSLQAECV 2606

Query: 773  KYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMD 832
              K +I  +E+       R+  L+     LG  + E Q      T  + +L + L  L +
Sbjct: 2607 NLKKQIQDVEQQ------RKDDLKSFEKMLGEGVNETQVI--GLTSDKQQLQSDLRQLQN 2658

Query: 833  HDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESE 892
                ++++  +I  +N+ LQK  QI+  +++  Q   S+ ++       K N   L E +
Sbjct: 2659 KCDQLQQE--QIALQNQLLQKNKQIVDLQDETKQ---SEKEEQIRG---KDNEIKLLEQQ 2710

Query: 893  STKYQTQLRDL-ESNLKRITHEHQT-LIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKY 950
                + Q ++L +   + +T   Q   I+Q+ KEI D E              +V+NE  
Sbjct: 2711 VQTAKDQYQELLDLQQQNLTPGGQKEKILQQTKEIHDQE--------------EVINELQ 2756

Query: 951  EKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELID-KHVQKQQTQSPDYTEQYIN 1009
            +K    V QL+ QL E +  +++   + E  NK   EL++ K  Q Q   +P+  E+  +
Sbjct: 2757 QKVETEVPQLQGQLSEAQEKLKDAQKDAELWNKKYHELLESKQTQVQNILAPEEIEKLSS 2816

Query: 1010 E--INKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRV 1067
            E   N L  L KQ  ++  A   K     V ++    D   +  Q   K    E+ +   
Sbjct: 2817 EEAKNALTQLNKQYSDK--AQENKELEMVVQHLRQDLDSSQEKVQQQAKEAQQEKSVLEQ 2874

Query: 1068 SKQLLDSKQHNEELQILVREQDDQIKELKETK 1099
              QLL     N +L+ LV +++ Q +E+ + K
Sbjct: 2875 QTQLL-----NNQLKDLVAKEEVQRQEILDLK 2901



 Score = 74.9 bits (176), Expect = 2e-11
 Identities = 116/584 (19%), Positives = 254/584 (43%), Gaps = 51/584 (8%)

Query: 1032 INNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSK---QLLDSKQHNEELQILVREQ 1088
            IN  Q    + V   + +L++   KL++ +++ +  +K   +LL+SKQ   +  IL  E+
Sbjct: 2334 INELQQKVETEVPQLQGQLSEAQEKLKDAQKDAELWNKKYHELLESKQTQVQ-NILAPEE 2392

Query: 1089 DDQI--KELKE--TKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKV 1144
             +++  +E K   T+L  + +    E   +   ++ +  D ++               KV
Sbjct: 2393 IEKLSSEEAKNALTQLNKQYSDKAQENKELEMVVQHLRQDLDSSQE------------KV 2440

Query: 1145 QEE-EEFIQERSVLQEQSAKLNTELQECYTK-IIQLETLNTELTGHDVVNQEQINQLKSK 1202
            Q++ +E  QE+SVL++Q+  LN +L++   K  +Q + +   L   + ++QE  +  K +
Sbjct: 2441 QQQAKEAQQEKSVLEQQTQLLNNQLKDLVAKEEVQRQEI---LDLKNKLDQENADFWKKQ 2497

Query: 1203 LEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLS 1262
             +QL+ +   + ST A        +  +R  +  E+  +   + +   +K     +    
Sbjct: 2498 YQQLSEKQPEISSTQAGDLQEQQVSQQEREVKPKEILNEE--RNQMICKKKMKNWKHNRY 2555

Query: 1263 AFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEI 1322
             F+  Y +L +S  +  Q++  K    +Q    Q    +K   + +LQ +  ++  QI+ 
Sbjct: 2556 QFKMNYSKLSNSQMNKLQQQIQKPQGNDQQIQFQTD-PEKVLQISSLQAECVNLKKQIQD 2614

Query: 1323 LRSEIEDEKVAF---------XXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNIN-- 1371
            +  + +D+  +F                         DLR       Q+Q++ I   N  
Sbjct: 2615 VEQQRKDDLKSFEKMLGEGVNETQVIGLTSDKQQLQSDLRQLQNKCDQLQQEQIALQNQL 2674

Query: 1372 -EENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQR 1430
             ++N Q+                R  D E K+LE   Q      +      +  +T   +
Sbjct: 2675 LQKNKQIVDLQDETKQSEKEEQIRGKDNEIKLLEQQVQTAKDQYQELLDLQQQNLTPGGQ 2734

Query: 1431 NDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEE 1490
             ++     +++ + E+ I +L  + E+E+  L+ ++ E     +  QK++E+   K  E 
Sbjct: 2735 KEKILQQTKEIHDQEEVINELQQKVETEVPQLQGQLSEAQEKLKDAQKDAELWNKKYHEL 2794

Query: 1491 LNVKIT--ESVSLNKQVAEL-NKALEEEVAKTNEMQT--ALENQEIEIVTLNDEITNLQN 1545
            L  K T  +++   +++ +L ++  +  + + N+  +  A EN+E+E+V     + +L+ 
Sbjct: 2795 LESKQTQVQNILAPEEIEKLSSEEAKNALTQLNKQYSDKAQENKELEMV-----VQHLRQ 2849

Query: 1546 MVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAEL 1589
             + +S  K+Q+    A   K   ++Q    +N +L D V + E+
Sbjct: 2850 DLDSSQEKVQQQAKEAQQEKSVLEQQ-TQLLNNQLKDLVAKEEV 2892



 Score = 52.8 bits (121), Expect = 8e-05
 Identities = 122/592 (20%), Positives = 255/592 (43%), Gaps = 66/592 (11%)

Query: 217  QMTKMQENF--IAMEAE-WKDEKQRLLKDIESKDVRISSLEEANKLL--EA--ARFEISL 269
            Q+++ QE       +AE W  +   LL+  +++   I + EE  KL   EA  A  +++ 
Sbjct: 2351 QLSEAQEKLKDAQKDAELWNKKYHELLESKQTQVQNILAPEEIEKLSSEEAKNALTQLNK 2410

Query: 270  EHSKLAQE---LEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTK 326
            ++S  AQE   LE                 +Q  + + +EK+ +E++  L    + +L  
Sbjct: 2411 QYSDKAQENKELEMVVQHLRQDLDSSQEKVQQQAKEAQQEKSVLEQQTQLLNNQLKDLVA 2470

Query: 327  KIELLEH----LNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKM 382
            K E+       L  ++ Q N +   K     +E +   S ++ G     + S +    K 
Sbjct: 2471 KEEVQRQEILDLKNKLDQENADFWKKQYQQLSEKQPEISSTQAGDLQEQQVSQQEREVKP 2530

Query: 383  KSPWSQLSSETLNQDTDK---------KINKNEIAKLEM--VIQSLNKDLVDKEYVISEK 431
            K   ++  ++ + +   K         K+N ++++  +M  + Q + K   + + +  + 
Sbjct: 2531 KEILNEERNQMICKKKMKNWKHNRYQFKMNYSKLSNSQMNKLQQQIQKPQGNDQQIQFQT 2590

Query: 432  DTXXXXXXXXXXGKDT-LIAQLQLEHQQHMEG----PSLIHVGTNTEDVNEIAKVQEQLK 486
            D            +   L  Q+Q   QQ  +       ++  G N   V  +   ++QL+
Sbjct: 2591 DPEKVLQISSLQAECVNLKKQIQDVEQQRKDDLKSFEKMLGEGVNETQVIGLTSDKQQLQ 2650

Query: 487  QELN------DEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKN-MIKVKSNH-KLKLK 538
             +L       D+++   +  L  +L    +QI  L DE   + K   I+ K N  KL  +
Sbjct: 2651 SDLRQLQNKCDQLQQEQIA-LQNQLLQKNKQIVDLQDETKQSEKEEQIRGKDNEIKLLEQ 2709

Query: 539  QMQKTIDNFSKVSD----------SNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDY 588
            Q+Q   D + ++ D            ++I++ T+E+H   + + EL+++       L   
Sbjct: 2710 QVQTAKDQYQELLDLQQQNLTPGGQKEKILQQTKEIHDQEEVINELQQKVETEVPQL--- 2766

Query: 589  DSGRMIESDVYKKMIEMENLAET-RLKAISLLESQKFDLVQEL---HILQQKYDEVEDKL 644
              G++  S+  +K+ + +  AE    K   LLES++  +   L    I +   +E ++ L
Sbjct: 2767 -QGQL--SEAQEKLKDAQKDAELWNKKYHELLESKQTQVQNILAPEEIEKLSSEEAKNAL 2823

Query: 645  ADISQLQSD--QVCSEIKSV--HLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLE 700
              +++  SD  Q   E++ V  HL + +D+   S++++    +  + +K  L    + L 
Sbjct: 2824 TQLNKQYSDKAQENKELEMVVQHLRQDLDS---SQEKVQQQAKEAQQEKSVLEQQTQLLN 2880

Query: 701  NDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFG 752
            N  +D++ K +   QE +DL +KL++ +A+   +   +++ ++     TQ G
Sbjct: 2881 NQLKDLVAKEEVQRQEILDLKNKLDQENADFWKKQYQQLSEKQPEISSTQAG 2932



 Score = 39.1 bits (87), Expect = 0.99
 Identities = 35/149 (23%), Positives = 76/149 (51%), Gaps = 11/149 (7%)

Query: 1446 KRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKIT--ESVSLNK 1503
            K I +L  + E+E+  L+ ++ E     +  QK++E+   K  E L  K T  +++   +
Sbjct: 2332 KLINELQQKVETEVPQLQGQLSEAQEKLKDAQKDAELWNKKYHELLESKQTQVQNILAPE 2391

Query: 1504 QVAEL-NKALEEEVAKTNEMQT--ALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSF 1560
            ++ +L ++  +  + + N+  +  A EN+E+E+V     + +L+  + +S  K+Q+    
Sbjct: 2392 EIEKLSSEEAKNALTQLNKQYSDKAQENKELEMV-----VQHLRQDLDSSQEKVQQQAKE 2446

Query: 1561 ASDTKQGRDEQLDNTMNKELLDAVPRAEL 1589
            A   K   ++Q    +N +L D V + E+
Sbjct: 2447 AQQEKSVLEQQ-TQLLNNQLKDLVAKEEV 2474


>UniRef50_A0BYX7 Cluster: Chromosome undetermined scaffold_138, whole
            genome shotgun sequence; n=2; Paramecium tetraurelia|Rep:
            Chromosome undetermined scaffold_138, whole genome
            shotgun sequence - Paramecium tetraurelia
          Length = 929

 Score =  126 bits (303), Expect = 7e-27
 Identities = 191/889 (21%), Positives = 399/889 (44%), Gaps = 87/889 (9%)

Query: 485  LKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTI 544
            LK+ +N+  KD  + DL +KL+  + ++ +  +E++A  +N      N+  ++ + +  I
Sbjct: 11   LKKTINE--KDQQIGDLEKKLRLEQFRVKKQQNELNAKIENEKSTAQNNADQINRFELQI 68

Query: 545  DNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIE 604
             +  K   + K I +L+E      +K  +L EE   L+       SG   E    KK  E
Sbjct: 69   SDL-KSKVAMKFIFKLSET----EKKNLQLIEEISALKKRRA---SGSTDEDFQPKK--E 118

Query: 605  MENLAETRLKAISLLESQKFDLVQELHILQQKYDEV-EDKLADISQLQSDQVCSEIKSVH 663
             +    +  + + ++++ + +   EL  + + Y E  + K   I+ L+      EIK   
Sbjct: 119  HQGDFPSLQQILGIIQANQGNYQPELTKMYECYTEACQSKDEQINSLKE-----EIKD-- 171

Query: 664  LEEQIDAL-SASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTD 722
            L +Q+D   S S K+L           EQL   IK L+   ++  N+L+N +Q+  D +D
Sbjct: 172  LTQQLDIKQSDSTKQL-----------EQLEERIKSLKQSLDERENELKNVVQQTSDNSD 220

Query: 723  K----LEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRI 778
            +    LEK    ++SE   ++    +      F ++ ++ E+   +E+ +++ +  + +I
Sbjct: 221  QKIQELEKQYQTQLSEKDKQLQETTKKAKFDVFKLNKQLTEQKTVVESEQAKTNLLQQQI 280

Query: 779  CRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVE 838
             R E S+   E +   LE+K   L    + KQK      + E+ L       +  D+   
Sbjct: 281  DRQESSLREFEIKLSELEQK--NLLLIEEAKQKQQEIERLNEESLTRVQVEEIPQDKPSY 338

Query: 839  KQLLEI--EHENKELQKKNQIL-LEENQNLQISLS-DMQQHYNALVEKANRTDLAESEST 894
            ++L+E   + +  E+  + ++  LEE  NL+ + S ++Q+  N  +EK    D    ES 
Sbjct: 339  EELVEFIQKFQVNEINYQQELKNLEEELNLKNTHSFELQEELNQYIEKVQLQDRKYQESM 398

Query: 895  KYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEF----------NTQIESAIRDKK 944
            +    L + + + +++  E Q  + Q K+E E  + EF          NT ++ A+ D +
Sbjct: 399  RAIKALEEQQISERQVAQELQHYVEQLKQEKEHQQAEFIHKIKELGEHNTNVDDAVNDVE 458

Query: 945  --------VLNEKYEKN----IEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKH 992
                    +  E+Y++     I  + Q E +L + +  ++      +   K + E   + 
Sbjct: 459  QKFQKMMMIQEEQYQRREQELIHQIEQSEEKLSQQEQLLKKQEQKYKNEIKQSEENNSQM 518

Query: 993  VQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALN-QKINNAQVSYMSMVSDYESKLA 1051
            +Q++Q Q     +Q  +E +K+     ++  E+   N +K  + +     +   YE +L+
Sbjct: 519  IQQKQLQVTQLQKQLQDETHKIREDSNKQINELKQENYKKEKSLEQKIQEVTKQYEGELS 578

Query: 1052 QFTTKLENMEEEMQRVSKQLLDSKQHNEE-LQILVREQDDQIKE----LKETKLTFEMNI 1106
            +   K+E + ++ +R   +  ++K+  EE LQIL  + +  I++    +KE ++  ++N 
Sbjct: 579  KIR-KMEIVLKKKEREIAEEKEAKKFAEEQLQILTEKSNKMIEQYDNKIKEIQIANQVNK 637

Query: 1107 P-KTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLN 1165
              +    I    +   S D N               L+ + + E   E + L E+   L 
Sbjct: 638  QDQHRNSIFDQRMSISSSDINKT-FEIEVLKAQIEQLQSKGDIELQAEINRLNERERALK 696

Query: 1166 TELQECYTKIIQLETLNTELTGHDVVNQ-----EQINQLK----SKLEQLNTE-NDNLLS 1215
             EL +   +I   E LN  +    +  +     ++IN LK    S+L+++N E N NL S
Sbjct: 697  KELLDLQNEIGN-ERLNFMVVQRQLEKEVESLHQEINNLKQDHQSELDEINKESNKNLSS 755

Query: 1216 TVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSV 1275
               + ++ I+    +   + ++  K+     E + +    +L++++ + E +  +L D  
Sbjct: 756  QKNDFQTKINKLEQKLELQASQFSKKQ-NDIEEEKENIIQQLKIKIKSLEEQIIELKD-- 812

Query: 1276 QSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILR 1324
            + + +  + ++VT +    LQ ++    E  R L+++  D+ N+I  L+
Sbjct: 813  KKTIKNNSQQVVTQDDTIQLQQEIVSLNEKERVLRKELLDLQNEIGNLK 861



 Score =  111 bits (267), Expect = 2e-22
 Identities = 169/787 (21%), Positives = 354/787 (44%), Gaps = 86/787 (10%)

Query: 534  KLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRM 593
            K ++K + + +D   K SDS K++ +L E +  L Q + E E E  N+     D    ++
Sbjct: 166  KEEIKDLTQQLD--IKQSDSTKQLEQLEERIKSLKQSLDERENELKNVVQQTSDNSDQKI 223

Query: 594  IESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSD 653
             E +   K  + + L+E   +     +  KFD+ +    L ++   VE + A  + LQ  
Sbjct: 224  QELE---KQYQTQ-LSEKDKQLQETTKKAKFDVFKLNKQLTEQKTVVESEQAKTNLLQQ- 278

Query: 654  QVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQ-N 712
            Q+  +  S+  E +I      +K L L+IE  K  K+Q      ++E   E+ + ++Q  
Sbjct: 279  QIDRQESSLR-EFEIKLSELEQKNL-LLIEEAK-QKQQ------EIERLNEESLTRVQVE 329

Query: 713  YIQENM----DLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIE 768
             I ++     +L + ++K    +I+      N EE+  ++     + + +E + YIE ++
Sbjct: 330  EIPQDKPSYEELVEFIQKFQVNEINYQQELKNLEEELNLKNTHSFELQ-EELNQYIEKVQ 388

Query: 769  SELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLA 828
             +  KY+  +     +I  +E+++ S  + A +L  Y+ E+ K   E+  Q+ E ++++ 
Sbjct: 389  LQDRKYQESM----RAIKALEEQQISERQVAQELQHYV-EQLKQEKEH--QQAEFIHKIK 441

Query: 829  VLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDL 888
             L +H+  V+  + ++E   ++ QK   I  E+ Q  +  L  + Q   +  + + +  L
Sbjct: 442  ELGEHNTNVDDAVNDVE---QKFQKMMMIQEEQYQRREQEL--IHQIEQSEEKLSQQEQL 496

Query: 889  AESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNE 948
             + +  KY+ +++  E N  ++  + Q  + Q +K+++D   +        I + K  N 
Sbjct: 497  LKKQEQKYKNEIKQSEENNSQMIQQKQLQVTQLQKQLQDETHKIREDSNKQINELKQENY 556

Query: 949  KYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELID----KHVQKQQTQ----- 999
            K EK++E   +++   ++Y+  +  +      L K   E+ +    K   ++Q Q     
Sbjct: 557  KKEKSLE--QKIQEVTKQYEGELSKIRKMEIVLKKKEREIAEEKEAKKFAEEQLQILTEK 614

Query: 1000 SPDYTEQYINEINKL---NALLKQKDEEIIALNQK--INNAQVSYMSMVSDYESKLAQFT 1054
            S    EQY N+I ++   N + KQ        +Q+  I+++ ++    +   ++++ Q  
Sbjct: 615  SNKMIEQYDNKIKEIQIANQVNKQDQHRNSIFDQRMSISSSDINKTFEIEVLKAQIEQLQ 674

Query: 1055 TK--------LENMEEEMQRVSKQLLDSKQH--NEELQILVREQD---------DQIKEL 1095
            +K        +  + E  + + K+LLD +    NE L  +V ++           +I  L
Sbjct: 675  SKGDIELQAEINRLNERERALKKELLDLQNEIGNERLNFMVVQRQLEKEVESLHQEINNL 734

Query: 1096 KETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERS 1155
            K+   +    I K     +SS         N ++             +   EEE   + +
Sbjct: 735  KQDHQSELDEINKESNKNLSSQKNDFQTKINKLEQKLELQASQFSKKQNDIEEE---KEN 791

Query: 1156 VLQEQSAKLNTELQECYTKIIQLETLNT-ELTGHDVVNQEQINQLKSKLEQLNTENDNLL 1214
            ++Q+   K+ + L+E   +II+L+   T +     VV Q+   QL+ ++  LN +   L 
Sbjct: 792  IIQQLKIKIKS-LEE---QIIELKDKKTIKNNSQQVVTQDDTIQLQQEIVSLNEKERVLR 847

Query: 1215 STVAELRSSI-----SSAVDQRGFE-IAELWKQHL--AQREADF-QKTEHELRVQLSAFE 1265
              + +L++ I     S  +  R  E ++E +KQ    AQ+E D+ ++   +L VQ +   
Sbjct: 848  KELLDLQNEIGNLKLSHTIKIRELETLSEQYKQEANHAQQEQDYAEQMAAKLSVQYAELA 907

Query: 1266 SKYEQLL 1272
             +YE ++
Sbjct: 908  MEYENVI 914



 Score =  102 bits (244), Expect = 9e-20
 Identities = 199/958 (20%), Positives = 404/958 (42%), Gaps = 113/958 (11%)

Query: 143  DVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXX 202
            D+  L  TI EKD  +  L+ K+++ +  +   Q ++N K      +N+ +T        
Sbjct: 7    DIQLLKKTINEKDQQIGDLEKKLRLEQFRVKKQQNELNAK-----IENEKSTAQNNADQI 61

Query: 203  XXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIES-KDVRISSLEEANKLLE 261
                      D K   +K+   FI   +E + +  +L+++I + K  R S   + +    
Sbjct: 62   NRFELQIS--DLK---SKVAMKFIFKLSETEKKNLQLIEEISALKKRRASGSTDED---- 112

Query: 262  AARFEISLEHSKLAQELEQXXXXXXXXXXXXX-XLAK--QSIEPSCEEKTEIEEKGSLEI 318
               F+   EH      L+Q               L K  +    +C+ K E       EI
Sbjct: 113  ---FQPKKEHQGDFPSLQQILGIIQANQGNYQPELTKMYECYTEACQSKDEQINSLKEEI 169

Query: 319  ANMTEL--------TKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLI 370
             ++T+         TK++E LE     ++Q+  E EN+L  +  ++              
Sbjct: 170  KDLTQQLDIKQSDSTKQLEQLEERIKSLKQSLDERENELKNVVQQT-------------- 215

Query: 371  SRKSGRNTASKMKSPWSQLSSETLN-QDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVIS 429
            S  S +      K   +QLS +    Q+T KK      AK +  +  LNK L +++ V+ 
Sbjct: 216  SDNSDQKIQELEKQYQTQLSEKDKQLQETTKK------AKFD--VFKLNKQLTEQKTVVE 267

Query: 430  EKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQEL 489
             +             +++ + + +++  + +E  +L+ +        E AK ++Q  + L
Sbjct: 268  SEQAKTNLLQQQIDRQESSLREFEIKLSE-LEQKNLLLI--------EEAKQKQQEIERL 318

Query: 490  NDE-IKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFS 548
            N+E +  V V+++ +   S EE    L + I     N I    N++ +LK +++      
Sbjct: 319  NEESLTRVQVEEIPQDKPSYEE----LVEFIQKFQVNEI----NYQQELKNLEE------ 364

Query: 549  KVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVD-YDSGRMIESDVYKKMIEMEN 607
            +++  N     L EEL+   +KV +L++ K    +  +   +  ++ E  V +   E+++
Sbjct: 365  ELNLKNTHSFELQEELNQYIEKV-QLQDRKYQESMRAIKALEEQQISERQVAQ---ELQH 420

Query: 608  LAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQ 667
              E +LK     E Q+ + + ++  L +    V+D + D+ Q     +  + +     EQ
Sbjct: 421  YVE-QLKQEK--EHQQAEFIHKIKELGEHNTNVDDAVNDVEQKFQKMMMIQEEQYQRREQ 477

Query: 668  --IDALSASKKELALVIENLKLDKEQLYGTIKDL-ENDKEDIMNKLQNYIQENMDLTDKL 724
              I  +  S+++L+   + LK  +++    IK   EN+ + I  K     Q    L D+ 
Sbjct: 478  ELIHQIEQSEEKLSQQEQLLKKQEQKYKNEIKQSEENNSQMIQQKQLQVTQLQKQLQDET 537

Query: 725  EKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEES 784
             K+  +   +    IN  +Q   + +  ++ KIQE     +  E ELSK +     L++ 
Sbjct: 538  HKIREDSNKQ----INELKQENYKKEKSLEQKIQE---VTKQYEGELSKIRKMEIVLKKK 590

Query: 785  IAVMEDRRYSLERKADQLGSYLQEKQKAYSEY--TIQEDELVNRLAVLMDHDRVVEKQLL 842
               + + + + +   +QL    ++  K   +Y   I+E ++ N++     H   +  Q +
Sbjct: 591  EREIAEEKEAKKFAEEQLQILTEKSNKMIEQYDNKIKEIQIANQVNKQDQHRNSIFDQRM 650

Query: 843  EIEHENKELQKKNQILLEENQNLQISLS-DMQQHYNAL--VEKANRTDLAE------SES 893
             I   +     + ++L  + + LQ     ++Q   N L   E+A + +L +      +E 
Sbjct: 651  SISSSDINKTFEIEVLKAQIEQLQSKGDIELQAEINRLNERERALKKELLDLQNEIGNER 710

Query: 894  TKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKV----LNEK 949
              +    R LE  ++ +  E   L    + E++++  E N  + S   D +     L +K
Sbjct: 711  LNFMVVQRQLEKEVESLHQEINNLKQDHQSELDEINKESNKNLSSQKNDFQTKINKLEQK 770

Query: 950  YEKNIEYVTQLEAQLQEYKNN-IENLNMNVEELNKMNLELIDKHVQK---QQTQSPDYTE 1005
             E      ++ +  ++E K N I+ L + ++ L +  +EL DK   K   QQ  + D T 
Sbjct: 771  LELQASQFSKKQNDIEEEKENIIQQLKIKIKSLEEQIIELKDKKTIKNNSQQVVTQDDTI 830

Query: 1006 QYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEE 1063
            Q   EI  LN   +   +E++ L  +I N ++S+   + + E+   Q+  +  + ++E
Sbjct: 831  QLQQEIVSLNEKERVLRKELLDLQNEIGNLKLSHTIKIRELETLSEQYKQEANHAQQE 888



 Score = 75.4 bits (177), Expect = 1e-11
 Identities = 133/724 (18%), Positives = 309/724 (42%), Gaps = 43/724 (5%)

Query: 907  LKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKY--EKNIEYVTQLEAQL 964
            LK+  +E    I   +K++  LE +F  + +    + K+ NEK   + N + + + E Q+
Sbjct: 11   LKKTINEKDQQIGDLEKKLR-LE-QFRVKKQQNELNAKIENEKSTAQNNADQINRFELQI 68

Query: 965  QEYKNNIE-NLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDE 1023
             + K+ +       + E  K NL+LI++    ++ ++   T++      +         +
Sbjct: 69   SDLKSKVAMKFIFKLSETEKKNLQLIEEISALKKRRASGSTDEDFQPKKEHQGDFPSLQQ 128

Query: 1024 EIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQI 1083
             +  +     N Q     M   Y         ++ +++EE++ +++QL D KQ +   Q+
Sbjct: 129  ILGIIQANQGNYQPELTKMYECYTEACQSKDEQINSLKEEIKDLTQQL-DIKQSDSTKQL 187

Query: 1084 LVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSD-------DANNVDXXXXXXX 1136
               + +++IK LK++    E  +         ++ + + +         +  D       
Sbjct: 188  --EQLEERIKSLKQSLDERENELKNVVQQTSDNSDQKIQELEKQYQTQLSEKDKQLQETT 245

Query: 1137 XXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQEC---YTKIIQLETLNTELTGHDVVNQ 1193
                    +  ++  ++++V++ + AK N   Q+     + + + E   +EL   +++  
Sbjct: 246  KKAKFDVFKLNKQLTEQKTVVESEQAKTNLLQQQIDRQESSLREFEIKLSELEQKNLLLI 305

Query: 1194 EQINQLKSKLEQLNTENDNLLST--VAELRSSISSAVDQ-RGFEIAEL-WKQHLAQREAD 1249
            E+  Q + ++E+LN E+   +    + + + S    V+  + F++ E+ ++Q L   E +
Sbjct: 306  EEAKQKQQEIERLNEESLTRVQVEEIPQDKPSYEELVEFIQKFQVNEINYQQELKNLEEE 365

Query: 1250 FQ-KTEH--ELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQ--NKLQDKEE 1304
               K  H  EL+ +L+ +  K  QL D     +     K +  +Q++  Q   +LQ   E
Sbjct: 366  LNLKNTHSFELQEELNQYIEKV-QLQDRKYQESMRAI-KALEEQQISERQVAQELQHYVE 423

Query: 1305 HLRNLQE-KYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQ 1363
             L+  +E + A+ I++I+ L     +   A                   +   Q      
Sbjct: 424  QLKQEKEHQQAEFIHKIKELGEHNTNVDDAVNDVEQKFQKMMMIQEEQYQRREQELIHQI 483

Query: 1364 EQSILNINEENAQLKKSSXXXXXXXXXXXXR----VNDAEAKVLELTHQLELKDSEIYQK 1419
            EQS   ++++   LKK                   +   + +V +L  QL+ +  +I + 
Sbjct: 484  EQSEEKLSQQEQLLKKQEQKYKNEIKQSEENNSQMIQQKQLQVTQLQKQLQDETHKIRED 543

Query: 1420 THEYTITLTQRNDEFE-NVRQQLVEYEKRIE-DLTYEKESELAILRLKMHENANHYETMQ 1477
            +++    L Q N + E ++ Q++ E  K+ E +L+  ++ E+ +L+ K  E A   E   
Sbjct: 544  SNKQINELKQENYKKEKSLEQKIQEVTKQYEGELSKIRKMEI-VLKKKEREIAEEKEA-- 600

Query: 1478 KESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLN 1537
            K+   E+++++ E + K+ E    + ++ E+   +  +V K ++ + ++ +Q + I + +
Sbjct: 601  KKFAEEQLQILTEKSNKMIE--QYDNKIKEIQ--IANQVNKQDQHRNSIFDQRMSISSSD 656

Query: 1538 DEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDLAMYMLH 1597
               T    +++A   ++Q         +  R  + +  + KELLD       +   +M+ 
Sbjct: 657  INKTFEIEVLKAQIEQLQSKGDIELQAEINRLNERERALKKELLDLQNEIGNERLNFMVV 716

Query: 1598 QRDV 1601
            QR +
Sbjct: 717  QRQL 720



 Score = 48.0 bits (109), Expect = 0.002
 Identities = 101/536 (18%), Positives = 223/536 (41%), Gaps = 57/536 (10%)

Query: 220 KMQENFIAMEAEWKDEKQRLLKDIESKDV--RISSLEEANKLLEAARFEISLEHSKLAQE 277
           ++ E  +A E +   E+ +  K+ +  +   +I  L E N  ++ A  ++  +  K+   
Sbjct: 408 QISERQVAQELQHYVEQLKQEKEHQQAEFIHKIKELGEHNTNVDDAVNDVEQKFQKMMMI 467

Query: 278 LEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQ 337
            E+               +++ +    +   + E+K   EI    E     ++++    Q
Sbjct: 468 QEEQYQRREQELIHQIEQSEEKLSQQEQLLKKQEQKYKNEIKQSEE--NNSQMIQQKQLQ 525

Query: 338 IRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQD 397
           + Q  K+L+++   +  +S    +  K+ +     K  ++   K++    Q   E     
Sbjct: 526 VTQLQKQLQDETHKIREDSNKQINELKQEN----YKKEKSLEQKIQEVTKQYEGEL---- 577

Query: 398 TDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQ 457
              KI K EI  L+   + + ++   K++   +               D  I ++Q+ +Q
Sbjct: 578 --SKIRKMEIV-LKKKEREIAEEKEAKKFAEEQLQILTEKSNKMIEQYDNKIKEIQIANQ 634

Query: 458 -----QHMEGPSLIHVGTNTEDVN-----EIAKVQEQLKQELNDEIKDVNVKDLIEKLKS 507
                QH        +  ++ D+N     E+ K Q +  Q   D      +  L E+ ++
Sbjct: 635 VNKQDQHRNSIFDQRMSISSSDINKTFEIEVLKAQIEQLQSKGDIELQAEINRLNERERA 694

Query: 508 AEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHL 567
            ++++  L +EI     N + V+   + +++ + + I+N  +  D   E+    +E++  
Sbjct: 695 LKKELLDLQNEIGNERLNFMVVQRQLEKEVESLHQEINNLKQ--DHQSEL----DEINKE 748

Query: 568 SQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLV 627
           S K   L  +K + Q             + + K   ++E  A    K  + +E +K +++
Sbjct: 749 SNK--NLSSQKNDFQ-------------TKINKLEQKLELQASQFSKKQNDIEEEKENII 793

Query: 628 QELHILQQKYDEVEDKLADISQLQ--SDQVCSEIKSVHLEEQIDALSASKKELALVIENL 685
           Q+L I  +  +E   +L D   ++  S QV ++  ++ L+++I  +S ++KE  L  E L
Sbjct: 794 QQLKIKIKSLEEQIIELKDKKTIKNNSQQVVTQDDTIQLQQEI--VSLNEKERVLRKELL 851

Query: 686 KLDKE----QLYGTIK--DLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISEL 735
            L  E    +L  TIK  +LE   E    +  N+ Q+  D  +++    + + +EL
Sbjct: 852 DLQNEIGNLKLSHTIKIRELETLSEQYKQE-ANHAQQEQDYAEQMAAKLSVQYAEL 906


>UniRef50_UPI00015B5164 Cluster: PREDICTED: similar to
            ENSANGP00000005723; n=1; Nasonia vitripennis|Rep:
            PREDICTED: similar to ENSANGP00000005723 - Nasonia
            vitripennis
          Length = 1515

 Score =  125 bits (302), Expect = 9e-27
 Identities = 250/1229 (20%), Positives = 539/1229 (43%), Gaps = 122/1229 (9%)

Query: 147  LSNTIKEKDNALSVLQVKMKI----------METTILDLQEKINEK-DQIIEAKNKATTX 195
            L N I+EKD+ ++ L+ K+K+          +ET  +    K  +K D +++  N +   
Sbjct: 210  LRNDIEEKDHVINSLRTKIKLIQEKSPNIEGLETVEISENHKEGDKVDILVDLSNNSEPD 269

Query: 196  XXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEE 255
                             +   +   ++ ++  ++   K++ + +  ++E+      +L E
Sbjct: 270  QPKKYKDMLKRSKDKMLEMTNEKNTLERDYDILQKSSKEKLESVESELENSKEGFKNLRE 329

Query: 256  ANKLLEAARFE--ISLEHSKLA--QELE------QXXXXXXXXXXXXXXLAKQSIE-PSC 304
               +L+    E  ISL  +KL+  +ELE      +                K+SIE    
Sbjct: 330  ELDVLKKREEESVISLAENKLSIHRELEGKEEQIKQLRSELKQTLEHEKALKESIETQKL 389

Query: 305  E-EKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPS 363
            E EK ++    + E AN   L  K E L+ +  +++Q   +LE    TMG +       +
Sbjct: 390  ELEKVKLVANQNAE-ANQEHLRGKSEALKKVQSEMQQKLIDLEE---TMGAK---YHEEA 442

Query: 364  KKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINK-NEIAKLEMVIQSLNKDLV 422
             K   L+S+       SK     +Q  SE L + T K  +K N++++L     ++ K+  
Sbjct: 443  NKNKELLSKIEELEKQSKE----TQHGSEALEKLTKKLQDKENQVSEL-----AIKKE-- 491

Query: 423  DKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQ 482
            + E ++ E  T               + ++Q E     E  S        +++NE+ K  
Sbjct: 492  EYEKLLEEYKTQNTNLNKEFTEIRNSLEKIQTE----TETSSNALKDKYEKEINELKKTL 547

Query: 483  EQLKQELNDEIKDVNVKDLIEKLK-SAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQ 541
            E+ K +++++  ++ +++  E  K S EE++ +L DE ++ N  ++ + S    +LK  +
Sbjct: 548  EE-KTDISEK-SNLKIQEYTEASKTSDEEKMLRLQDEFESKNTEILGLNS----ELKSYR 601

Query: 542  KTIDNFSK-VSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVD-YDSGRMIESDVY 599
             TI +  K ++        L + L    + V  L+++  +L+  +      G+   SD  
Sbjct: 602  TTITDLKKEINILANHRQNLVKNLKSCKKAVKGLKQDCASLKNDVHSRISEGKCAISDAV 661

Query: 600  KKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEI 659
            +K + +  + + +   I+ L+SQ  +L ++   L++      D     S +Q +++ SE 
Sbjct: 662  EKTVNVFPMMDEK---INNLQSQIVELTEKTKTLEEFNRNCSD-----SNVQLEKILSE- 712

Query: 660  KSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMD 719
              + LE+++ A    K+     I+   +D  +L      L++D E++  K+  Y +   +
Sbjct: 713  -KMALEKELQA----KQHEVETIQAKLIDFGELKENNGKLQSDIENLNFKISEYEKLCTE 767

Query: 720  LTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRIC 779
             + ++++   EK   LL  I  ++Q           K+ ++++  +    E +K    I 
Sbjct: 768  HSMEIQEAKLEK-DNLLKDITLKKQHNESLIQEFSQKLSDKEVITQEFHEERNKLIHEIQ 826

Query: 780  RLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEK 839
             LE  +A +++    L +K  +L  YLQ K     E T +          L++ +     
Sbjct: 827  VLEFELASIKE---ELGKKNTEL-QYLQTKTTEEGEQTDKITNECENYKKLLEENNQTLS 882

Query: 840  QLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHY------NALVEKANRTDLAESES 893
            QL E    +K+ + K +I L+E+++      D +  +      + L       D  ++E 
Sbjct: 883  QLNEELKNSKDERDKIRIELQESKDSLQKAMDTKNGFLQKLKLDELKSSKGELDSLKNEK 942

Query: 894  TKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFN---TQIESAIRDKKVLNEKY 950
                 +L++++S L  + H     +   + ++  L    N   +++   +R+ +  N+  
Sbjct: 943  VIMAEELKEIKS-LHDLLHNENKSLKDNQNDLLRLNEVLNQSQSELTEKLRNLEKKNDDI 1001

Query: 951  EK-NIEYVTQLEA---QLQEYKNNIENLN---MNVEELNKMNLE---LIDKHVQKQQTQS 1000
             K N  ++T++E    QL+   + IENL      +E++ K N E   L+++    QQ  +
Sbjct: 1002 AKENNAFLTEIETFKYQLKNAHSEIENLKSQLAELEDMRKKNNELSILLNEANNHQQNSA 1061

Query: 1001 PDYTE-QYINEINK-LNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLE 1058
              +TE + + + N+ LN+ L+  + +I+AL +K + A V+    +     ++ +    L 
Sbjct: 1062 QLFTEVERLTDTNRSLNSELQNLNNKILAL-EKQHEASVNLEHELQVCRDRIVELENNLS 1120

Query: 1059 NMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTI 1118
            +  +E+   S    +++ HN  +++  +       ELK TKL  E++       + SS +
Sbjct: 1121 SKIQELNSFSSN-SENECHNLRIELEEKNGVLNEMELKNTKLLEEID------QLSSSKL 1173

Query: 1119 EPMSDDANNVDXXXXXXXXXXXXLKVQEEE--EFIQER-SVLQEQSAKLNTELQECYTKI 1175
            +        ++            L  +EE   + IQ+  S  ++  ++L+  L     K 
Sbjct: 1174 DSEEKANQEINKLREASIEFEKNLSDKEENLTKNIQDAISEKRKIESQLDETLVTFQAKE 1233

Query: 1176 IQLETLNTELTGHDVVNQEQ--INQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGF 1233
             Q++ LN EL       +EQ  IN+ +  L +L        + + +    + +A+++R F
Sbjct: 1234 TQMQVLNEELRNQAAKLREQLKINEEEQSL-RLKQIVKEFQAQLHDKEKELQAALEKR-F 1291

Query: 1234 EIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLL---DSVQSSTQEETNKIVTME 1290
            +  + ++  + Q   ++++   + +V+L+    + E+L+   ++ +   QEE  K+  ++
Sbjct: 1292 DRQQNYESDIIQ---EYREQLKDFQVELTKKSEEIERLILNNENTKKEAQEEFEKL--LD 1346

Query: 1291 QVTSLQNKLQDKEEHLRNLQEKYADVINQ 1319
             +   Q KL+ KEE ++ L+ ++  ++NQ
Sbjct: 1347 NIN--QIKLEHKEE-IQELERRWKHIVNQ 1372



 Score =  112 bits (270), Expect = 7e-23
 Identities = 206/1112 (18%), Positives = 466/1112 (41%), Gaps = 79/1112 (7%)

Query: 500  DLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVR 559
            DL+   +  E   T+L   +       ++  S+ K + +  Q+   +  +      +I  
Sbjct: 159  DLVTHYREIERAKTKLESLLVETQDKALRRISDLKEQCQLEQQAKAHLEEAL--RNDIEE 216

Query: 560  LTEELHHLSQKVAELEEEKGNLQ-LHLVDYDSGRMIESDVYKKMIEMENLAETRL--KAI 616
                ++ L  K+  ++E+  N++ L  V+       E D    ++++ N +E     K  
Sbjct: 217  KDHVINSLRTKIKLIQEKSPNIEGLETVEISENHK-EGDKVDILVDLSNNSEPDQPKKYK 275

Query: 617  SLLESQK---FDLVQELHILQQKYDEVEDKLAD-ISQLQSDQVCSEIKSVHLEEQIDALS 672
             +L+  K    ++  E + L++ YD ++    + +  ++S+   S+    +L E++D L 
Sbjct: 276  DMLKRSKDKMLEMTNEKNTLERDYDILQKSSKEKLESVESELENSKEGFKNLREELDVLK 335

Query: 673  ASKKELALVIENLKLD-KEQLYGTIKDLENDKEDIMNKLQNY--IQENMDLTDKLEKMSA 729
              ++E  + +   KL    +L G  + ++  + ++   L++   ++E+++ T KLE    
Sbjct: 336  KREEESVISLAENKLSIHRELEGKEEQIKQLRSELKQTLEHEKALKESIE-TQKLELEKV 394

Query: 730  EKISELLAKINHEE-QSKIQTQFGIDAKIQERDLYIENI-----ESELSKYKSRICRLEE 783
            + ++   A+ N E  + K +    + +++Q++ + +E         E +K K  + ++EE
Sbjct: 395  KLVANQNAEANQEHLRGKSEALKKVQSEMQQKLIDLEETMGAKYHEEANKNKELLSKIEE 454

Query: 784  SIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLE 843
                 ++ ++  E   ++L   LQ+K+   SE  I+++E    L      +  + K+  E
Sbjct: 455  LEKQSKETQHGSEA-LEKLTKKLQDKENQVSELAIKKEEYEKLLEEYKTQNTNLNKEFTE 513

Query: 844  IEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDL 903
            I +  +++Q + +     N        ++ +    L EK   TD++E  + K Q      
Sbjct: 514  IRNSLEKIQTETET--SSNALKDKYEKEINELKKTLEEK---TDISEKSNLKIQEYTEAS 568

Query: 904  ESNLKRITHEHQTLIVQKKKEIEDLEIE---FNTQIESAIRDKKVLNEKYEKNIEYVTQL 960
            +++ +      Q     K  EI  L  E   + T I    ++  +L    +  ++ +   
Sbjct: 569  KTSDEEKMLRLQDEFESKNTEILGLNSELKSYRTTITDLKKEINILANHRQNLVKNLKSC 628

Query: 961  EAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQ 1020
            +  ++  K +  +L  +V          I   V+K     P   E+ IN +      L +
Sbjct: 629  KKAVKGLKQDCASLKNDVHSRISEGKCAISDAVEKTVNVFPMMDEK-INNLQSQIVELTE 687

Query: 1021 KDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDS---KQH 1077
            K + +   N+  +++ V    ++S+   K+A    +L+  + E++ +  +L+D    K++
Sbjct: 688  KTKTLEEFNRNCSDSNVQLEKILSE---KMA-LEKELQAKQHEVETIQAKLIDFGELKEN 743

Query: 1078 NEELQILVREQDDQIKELKE--TKLTFEMNIPKTE--GMIISSTIEPMSDDANNVDXXXX 1133
            N +LQ  +   + +I E ++  T+ + E+   K E   ++   T++   +++   +    
Sbjct: 744  NGKLQSDIENLNFKISEYEKLCTEHSMEIQEAKLEKDNLLKDITLKKQHNESLIQEFSQK 803

Query: 1134 XXXXXXXXLKVQEEE-EFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVN 1192
                     +  EE  + I E  VL+ + A +  EL +  T++  L+T  TE        
Sbjct: 804  LSDKEVITQEFHEERNKLIHEIQVLEFELASIKEELGKKNTELQYLQTKTTE-------E 856

Query: 1193 QEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQK 1252
             EQ +++ ++ E      +    T+++L   + ++ D+R     EL +   + ++A   K
Sbjct: 857  GEQTDKITNECENYKKLLEENNQTLSQLNEELKNSKDERDKIRIELQESKDSLQKAMDTK 916

Query: 1253 TEHELRVQLSAFESKYEQLLDSVQSST---QEETNKIVTMEQVTSLQNK-LQDKEEHLRN 1308
                 +++L   +S   +L DS+++      EE  +I ++  +   +NK L+D +  L  
Sbjct: 917  NGFLQKLKLDELKSSKGEL-DSLKNEKVIMAEELKEIKSLHDLLHNENKSLKDNQNDLLR 975

Query: 1309 LQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSIL 1368
            L E    V+NQ +   SE+ ++                    D+  EN ++  + E    
Sbjct: 976  LNE----VLNQSQ---SELTEK-----------LRNLEKKNDDIAKENNAF--LTEIETF 1015

Query: 1369 NINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLT 1428
                +NA  +  +            + N+  + +L   +  +   ++++ +    T T  
Sbjct: 1016 KYQLKNAHSEIENLKSQLAELEDMRKKNNELSILLNEANNHQQNSAQLFTEVERLTDTNR 1075

Query: 1429 QRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLI 1488
              N E +N+  +++  EK+ E  +   E EL + R ++ E  N+  +  +E         
Sbjct: 1076 SLNSELQNLNNKILALEKQHE-ASVNLEHELQVCRDRIVELENNLSSKIQELNSFSSNSE 1134

Query: 1489 EE---LNVKITESVS-LNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQ 1544
             E   L +++ E    LN+   +  K LEE    ++    + E    EI  L +     +
Sbjct: 1135 NECHNLRIELEEKNGVLNEMELKNTKLLEEIDQLSSSKLDSEEKANQEINKLREASIEFE 1194

Query: 1545 NMVRASSSKIQKHVSFASDTKQGRDEQLDNTM 1576
              +      + K++  A   K+  + QLD T+
Sbjct: 1195 KNLSDKEENLTKNIQDAISEKRKIESQLDETL 1226



 Score =  105 bits (251), Expect = 1e-20
 Identities = 205/1054 (19%), Positives = 440/1054 (41%), Gaps = 82/1054 (7%)

Query: 573  ELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHI 632
            E+E  K  L+  LV+     +      K+  ++E  A+  L+     + ++ D V  ++ 
Sbjct: 166  EIERAKTKLESLLVETQDKALRRISDLKEQCQLEQQAKAHLEEALRNDIEEKDHV--INS 223

Query: 633  LQQKYDEVEDKLADISQLQSDQVCSEIKSVH-LEEQIDALSASKKELALVIEN-LKLDKE 690
            L+ K   +++K  +I  L++ ++    K    ++  +D  + S+ +     ++ LK  K+
Sbjct: 224  LRTKIKLIQEKSPNIEGLETVEISENHKEGDKVDILVDLSNNSEPDQPKKYKDMLKRSKD 283

Query: 691  QLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKIN----HEEQSK 746
            ++     + +N  E   + LQ   +E ++  +   + S E    L  +++     EE+S 
Sbjct: 284  KMLEMTNE-KNTLERDYDILQKSSKEKLESVESELENSKEGFKNLREELDVLKKREEESV 342

Query: 747  I---QTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLG 803
            I   + +  I  +++ ++  I+ + SEL +       L+ESI   +     ++  A+Q  
Sbjct: 343  ISLAENKLSIHRELEGKEEQIKQLRSELKQTLEHEKALKESIETQKLELEKVKLVANQNA 402

Query: 804  SYLQEKQKAYSEYTIQ-EDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEEN 862
               QE  +  SE   + + E+  +L   +D +  +  +  E  ++NKEL  K + L +++
Sbjct: 403  EANQEHLRGKSEALKKVQSEMQQKL---IDLEETMGAKYHEEANKNKELLSKIEELEKQS 459

Query: 863  QNLQISLSDMQQHYNALVEKANR-TDLA--ESESTKYQTQLRDLESNLKRITHEHQTLIV 919
            +  Q     +++    L +K N+ ++LA  + E  K   + +   +NL +   E +  + 
Sbjct: 460  KETQHGSEALEKLTKKLQDKENQVSELAIKKEEYEKLLEEYKTQNTNLNKEFTEIRNSLE 519

Query: 920  QKKKEIEDLEIEFNTQIESAIRD-KKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNV 978
            + + E E        + E  I + KK L EK + + +   +++   +  K + E   + +
Sbjct: 520  KIQTETETSSNALKDKYEKEINELKKTLEEKTDISEKSNLKIQEYTEASKTSDEEKMLRL 579

Query: 979  -EELNKMNLEL--IDKHVQKQQTQSPDYTEQ---YINEINKLNALLKQKDEEIIALNQKI 1032
             +E    N E+  ++  ++  +T   D  ++     N    L   LK   + +  L Q  
Sbjct: 580  QDEFESKNTEILGLNSELKSYRTTITDLKKEINILANHRQNLVKNLKSCKKAVKGLKQDC 639

Query: 1033 NNAQVSYMSMVSDYESKLAQFTTKLEN----MEEEMQRVSKQLLDSKQHNEELQILVREQ 1088
             + +    S +S+ +  ++    K  N    M+E++  +  Q+++  +  + L+   R  
Sbjct: 640  ASLKNDVHSRISEGKCAISDAVEKTVNVFPMMDEKINNLQSQIVELTEKTKTLEEFNRNC 699

Query: 1089 DD---QIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXL--K 1143
             D   Q++++   K+  E  +   +  +   TI+    D   +             L  K
Sbjct: 700  SDSNVQLEKILSEKMALEKELQAKQHEV--ETIQAKLIDFGELKENNGKLQSDIENLNFK 757

Query: 1144 VQEEEEFIQERSV-LQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSK 1202
            + E E+   E S+ +QE   + +  L++   K    E+L  E +   + ++E I Q    
Sbjct: 758  ISEYEKLCTEHSMEIQEAKLEKDNLLKDITLKKQHNESLIQEFS-QKLSDKEVITQ---- 812

Query: 1203 LEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAEL-WKQHLAQREAD-FQKTEHELRVQ 1260
              + + E + L+  +  L   ++S  ++ G +  EL + Q     E +   K  +E    
Sbjct: 813  --EFHEERNKLIHEIQVLEFELASIKEELGKKNTELQYLQTKTTEEGEQTDKITNECENY 870

Query: 1261 LSAFESKYE---QLLDSVQSSTQEETN-KIVTMEQVTSLQNKLQDKE--------EHLRN 1308
                E   +   QL + +++S  E    +I   E   SLQ  +  K         + L++
Sbjct: 871  KKLLEENNQTLSQLNEELKNSKDERDKIRIELQESKDSLQKAMDTKNGFLQKLKLDELKS 930

Query: 1309 LQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTE---NQSYKQMQEQ 1365
             + +   + N+  I+  E+++ K                    LR     NQS  ++ E+
Sbjct: 931  SKGELDSLKNEKVIMAEELKEIKSLHDLLHNENKSLKDNQNDLLRLNEVLNQSQSELTEK 990

Query: 1366 SILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQL-ELKDSEIYQKTHEYT 1424
             + N+ ++N  + K +            ++ +A +++  L  QL EL+D  + +K +E +
Sbjct: 991  -LRNLEKKNDDIAKENNAFLTEIETFKYQLKNAHSEIENLKSQLAELED--MRKKNNELS 1047

Query: 1425 ITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIER 1484
            I L + N+  +N  Q   E E R+ D      SEL  L        N    ++K+ E   
Sbjct: 1048 ILLNEANNHQQNSAQLFTEVE-RLTDTNRSLNSELQNLN-------NKILALEKQHEAS- 1098

Query: 1485 VKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQ 1544
            V L  EL V          ++ EL   L  ++ + N   +  EN+   +    +E   + 
Sbjct: 1099 VNLEHELQV-------CRDRIVELENNLSSKIQELNSFSSNSENECHNLRIELEEKNGVL 1151

Query: 1545 NMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNK 1578
            N +   ++K+ + +   S +K   +E+ +  +NK
Sbjct: 1152 NEMELKNTKLLEEIDQLSSSKLDSEEKANQEINK 1185



 Score = 85.4 bits (202), Expect = 1e-14
 Identities = 212/1069 (19%), Positives = 430/1069 (40%), Gaps = 111/1069 (10%)

Query: 50   RQIKFERAQKCLENAALVSKRIKEHRKATAELLGRPFVPGISESLANTLKQKEILMEKIK 109
            ++++ E  QK ++    +  +  E      ELL +  +  + +    T    E L +  K
Sbjct: 417  KKVQSEMQQKLIDLEETMGAKYHEEANKNKELLSK--IEELEKQSKETQHGSEALEKLTK 474

Query: 110  QYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNALSVLQVKMKIME 169
            + ++   + S   ++                    T+L+    E  N+L  +Q + +   
Sbjct: 475  KLQDKENQVSELAIKKEEYEKLLEEYKTQN-----TNLNKEFTEIRNSLEKIQTETETSS 529

Query: 170  TTILDLQEK-INEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAM 228
              + D  EK INE  + +E K   +                  E+   +M ++Q+ F + 
Sbjct: 530  NALKDKYEKEINELKKTLEEKTDISEKSNLKIQEYTEASKTSDEE---KMLRLQDEFESK 586

Query: 229  EAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEI--SLEHSKLAQE-LEQXXXXX 285
              E       L  +++S    I+ L++   +L   R  +  +L+  K A + L+Q     
Sbjct: 587  NTEILG----LNSELKSYRTTITDLKKEINILANHRQNLVKNLKSCKKAVKGLKQDCASL 642

Query: 286  XXXXXXXXXLAKQSIEPSCEEKTEI----EEKGSLEIANMTELTKKIELLEHLNCQIRQT 341
                       K +I  + E+   +    +EK +   + + ELT+K + LE  N     +
Sbjct: 643  KNDVHSRISEGKCAISDAVEKTVNVFPMMDEKINNLQSQIVELTEKTKTLEEFNRNCSDS 702

Query: 342  N--------------KELENKLATMGT-ESKAVSSPSKKGSPLISRKSGRNTASKMKSPW 386
            N              KEL+ K   + T ++K +     K +    +    N   K+ S +
Sbjct: 703  NVQLEKILSEKMALEKELQAKQHEVETIQAKLIDFGELKENNGKLQSDIENLNFKI-SEY 761

Query: 387  SQLSSETLNQDTDKKINKNEIAK--------LEMVIQSLNKDLVDKEYVISE-------- 430
             +L +E   +  + K+ K+ + K         E +IQ  ++ L DKE +  E        
Sbjct: 762  EKLCTEHSMEIQEAKLEKDNLLKDITLKKQHNESLIQEFSQKLSDKEVITQEFHEERNKL 821

Query: 431  ------KDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQ 484
                   +            K+T +  LQ +  +  EG     +    E+  ++ +   Q
Sbjct: 822  IHEIQVLEFELASIKEELGKKNTELQYLQTKTTE--EGEQTDKITNECENYKKLLEENNQ 879

Query: 485  LKQELNDEIKDVNVKDLIEKLK-SAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKT 543
               +LN+E+K  N KD  +K++   +E    L   +D  N  + K+K +     K    +
Sbjct: 880  TLSQLNEELK--NSKDERDKIRIELQESKDSLQKAMDTKNGFLQKLKLDELKSSKGELDS 937

Query: 544  IDNFSKV-SDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKM 602
            + N   + ++  KEI  L + LH+ ++ + + + +   L+L+ V   S   +   +    
Sbjct: 938  LKNEKVIMAEELKEIKSLHDLLHNENKSLKDNQNDL--LRLNEVLNQSQSELTEKLRNLE 995

Query: 603  IEMENLAETRLKAISLLESQKFDLVQ---ELHILQQKYDEVED---KLADISQLQSDQVC 656
             + +++A+     ++ +E+ K+ L     E+  L+ +  E+ED   K  ++S L ++   
Sbjct: 996  KKNDDIAKENNAFLTEIETFKYQLKNAHSEIENLKSQLAELEDMRKKNNELSILLNEANN 1055

Query: 657  SEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQE 716
             +  S  L  +++ L+ + + L   ++NL          I  LE   E  +N L++ +Q 
Sbjct: 1056 HQQNSAQLFTEVERLTDTNRSLNSELQNLN-------NKILALEKQHEASVN-LEHELQV 1107

Query: 717  NMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAK---IQERDLYIENIESELSK 773
              D   +LE   + KI EL +  ++ E      +  ++ K   + E +L    +  E+ +
Sbjct: 1108 CRDRIVELENNLSSKIQELNSFSSNSENECHNLRIELEEKNGVLNEMELKNTKLLEEIDQ 1167

Query: 774  YKSRICRLEESI--AVMEDRRYSLERK---ADQLGSYLQEKQKAYSEYTIQEDELVNRLA 828
              S     EE     + + R  S+E +   +D+  +  +  Q A SE    E +L   L 
Sbjct: 1168 LSSSKLDSEEKANQEINKLREASIEFEKNLSDKEENLTKNIQDAISEKRKIESQLDETLV 1227

Query: 829  VLMDHDRVVEKQLLEIEHENKELQKKNQILL-EENQNL---------QISLSDMQQHYNA 878
                 +   + Q+L  E  N+  + + Q+ + EE Q+L         Q  L D ++   A
Sbjct: 1228 TFQAKE--TQMQVLNEELRNQAAKLREQLKINEEEQSLRLKQIVKEFQAQLHDKEKELQA 1285

Query: 879  LVEKA-NRTDLAESESTK-YQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQI 936
             +EK  +R    ES+  + Y+ QL+D +  L + + E + LI+  +   ++ + EF   +
Sbjct: 1286 ALEKRFDRQQNYESDIIQEYREQLKDFQVELTKKSEEIERLILNNENTKKEAQEEFEKLL 1345

Query: 937  ESA----IRDKKVLNEKYEKNIEYVTQLEAQLQ-EYKNNIENLN--MNVEELNKMNLELI 989
            ++     +  K+ + E   +    V Q  +QL+ ++++ I  L      E  N  N EL+
Sbjct: 1346 DNINQIKLEHKEEIQELERRWKHIVNQKTSQLETKHEHEIAELTNEWKNERKNDENTELL 1405

Query: 990  DKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVS 1038
            DK ++     +    +      + L   L  +  E+  L + +   Q S
Sbjct: 1406 DKELESTTRVAMAAVQSNTGSFHTLQQTLLSQKRELAELRKLVKLRQES 1454



 Score = 78.6 bits (185), Expect = 1e-12
 Identities = 129/719 (17%), Positives = 300/719 (41%), Gaps = 60/719 (8%)

Query: 859  LEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLE---SNLKRITHEHQ 915
            +++N + Q+     +Q Y+A  +   + D      +   T  R++E   + L+ +  E Q
Sbjct: 123  IDDNISPQLDRVSKEQLYSAYRKARTKYDKYRGRFSDLVTHYREIERAKTKLESLLVETQ 182

Query: 916  TLIVQKKKEIED---LEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIE 972
               +++  ++++   LE +    +E A+R+   + EK        T+++  +QE   NIE
Sbjct: 183  DKALRRISDLKEQCQLEQQAKAHLEEALRND--IEEKDHVINSLRTKIKL-IQEKSPNIE 239

Query: 973  NLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKI 1032
             L       N    + +D  V       PD  ++Y         +LK+  ++++ +  + 
Sbjct: 240  GLETVEISENHKEGDKVDILVDLSNNSEPDQPKKY-------KDMLKRSKDKMLEMTNEK 292

Query: 1033 NNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQI 1092
            N  +  Y  +    + KL    ++LEN +E            K   EEL +L + +++ +
Sbjct: 293  NTLERDYDILQKSSKEKLESVESELENSKEGF----------KNLREELDVLKKREEESV 342

Query: 1093 KELKETKLTFEMNIPKTEGMI--ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEF 1150
              L E KL+    +   E  I  + S ++   +    +             +K+   +  
Sbjct: 343  ISLAENKLSIHRELEGKEEQIKQLRSELKQTLEHEKALKESIETQKLELEKVKLVANQNA 402

Query: 1151 IQERSVLQEQSAKLNTELQECYTKIIQL-ETLNTELTGHDVVNQEQINQLKSKLEQLNTE 1209
               +  L+ +S  L     E   K+I L ET+  +   H+  N+ +  +L SK+E+L  +
Sbjct: 403  EANQEHLRGKSEALKKVQSEMQQKLIDLEETMGAKY--HEEANKNK--ELLSKIEELEKQ 458

Query: 1210 NDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYE 1269
            +       +E    ++  +  +  +++E     LA ++ +++K   E + Q +    ++ 
Sbjct: 459  SKE-TQHGSEALEKLTKKLQDKENQVSE-----LAIKKEEYEKLLEEYKTQNTNLNKEFT 512

Query: 1270 QLLDSVQS-STQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQ-IEILRSEI 1327
            ++ +S++   T+ ET+     ++     N+L+   E   ++ EK    I +  E  ++  
Sbjct: 513  EIRNSLEKIQTETETSSNALKDKYEKEINELKKTLEEKTDISEKSNLKIQEYTEASKTSD 572

Query: 1328 EDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQ-SILNINEEN--AQLKKSSXXX 1384
            E++ +                  +L++   +   ++++ +IL  + +N    LK      
Sbjct: 573  EEKMLRLQDEFESKNTEILGLNSELKSYRTTITDLKKEINILANHRQNLVKNLKSCKKAV 632

Query: 1385 XXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEY 1444
                       ND  +++ E    +    S+  +KT      + ++ +  ++   +L E 
Sbjct: 633  KGLKQDCASLKNDVHSRISEGKCAI----SDAVEKTVNVFPMMDEKINNLQSQIVELTEK 688

Query: 1445 EKRIEDLTYE-KESELAILRLKMHENANHYETMQKESEIERV--KLIE-----ELNVKIT 1496
             K +E+      +S + + ++   + A   E   K+ E+E +  KLI+     E N K+ 
Sbjct: 689  TKTLEEFNRNCSDSNVQLEKILSEKMALEKELQAKQHEVETIQAKLIDFGELKENNGKLQ 748

Query: 1497 ESV-SLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKI 1554
              + +LN +++E  K   E   +  E +   +N  ++ +TL  +  + +++++  S K+
Sbjct: 749  SDIENLNFKISEYEKLCTEHSMEIQEAKLEKDNL-LKDITLKKQ--HNESLIQEFSQKL 804


>UniRef50_UPI00006CB7E3 Cluster: Viral A-type inclusion protein repeat
            containing protein; n=1; Tetrahymena thermophila
            SB210|Rep: Viral A-type inclusion protein repeat
            containing protein - Tetrahymena thermophila SB210
          Length = 2645

 Score =  125 bits (302), Expect = 9e-27
 Identities = 267/1421 (18%), Positives = 622/1421 (43%), Gaps = 133/1421 (9%)

Query: 235  EKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXX 294
            EK   +  +E + +R ++LE  N+ L+     ++ +  +L +ELE               
Sbjct: 1277 EKTNKIIQLEQR-LRDNTLEYQNQALQQKVNLLTEQIERLVRELENARNELIQVSRKC-- 1333

Query: 295  LAKQSIEPSCEEKTEIEEKGSLE--IANMTELTKKIELLEHLNCQIRQTNKELENKLATM 352
               QS+E   E++T   ++   E  IA +    +++        +++++ +  +N++A +
Sbjct: 1334 ---QSLE--IEKQTWDAQRAQYEQTIAQLHAEIQRLREQADEGEKVKRSKQNQDNRVAQL 1388

Query: 353  GTESKAVSSPSKK----GSPLISRKSGRN-TASKMKSPWSQLSSETLNQDTDKKINKNEI 407
              E+K +    +K     + L+ + S    T  ++++  +  + +  NQ+   ++N  + 
Sbjct: 1389 EAENKYLQDQLEKLRNDNNQLLQQVSQLTLTLQQLQAKLNDNTLQIQNQELQNRLNA-KT 1447

Query: 408  AKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIH 467
            A+LE V Q L +       +I+E             G +     L+   Q+      ++ 
Sbjct: 1448 AELERVAQELQR----LSQLINELTLEVNRLKSENAGFEVTKRALEGRIQELASRLEML- 1502

Query: 468  VGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMI 527
                T ++N + ++  +L  +L+       + +   +L  A      L++ +     ++I
Sbjct: 1503 ----TGEINRLNQLNGELSYKLSSS---ATINERYARLSDAYVLQCALSESLSKKVSDLI 1555

Query: 528  KVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHL-SQKVAELEEEK---GNLQL 583
              ++      K+ Q+        S  N+ +++   +L  L ++K  EL+  K    N+ +
Sbjct: 1556 GFQNEADEHRKRAQRQ-------SQDNEALIQRINQLEQLLAEKDRELQNLKVASQNVSI 1608

Query: 584  HLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDK 643
              +        + ++ K++ E+EN+   R K I+ L +       ++++LQ +  + E++
Sbjct: 1609 LQMQLQQSNQDKENLIKRIRELENILGERDKEIAGLRNAN----SQVNLLQIQIQQYENQ 1664

Query: 644  LADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDK 703
            + D+ +  +D    E+++V  + +    S   +E+  +     +  ++L   I+  ++  
Sbjct: 1665 INDLKRRHAD----ELENVKRQYEGLRQSTVNREINELTVKFNIRIQELEREIQKYKSLS 1720

Query: 704  EDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLY 763
            E   N+L+   Q+N +L  +L  + AE  +      + +EQ K +++ G   ++   +  
Sbjct: 1721 EQYENELRAQRQQNSELLQRL--VDAENRAR-----DSDEQVK-RSRAG-QQQVNNLEEN 1771

Query: 764  IENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDEL 823
            +  + +EL K K+ +   +   A +E ++  L  + ++L + L+EK     ++  +E E 
Sbjct: 1772 LRFVTAELEKQKNLLAEEKNKNAQLESQKSILAMEIERLNTILKEKLILIEDFQRREAEY 1831

Query: 824  VNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLE---ENQNLQISLSDMQQHYNALV 880
             N+L  L      V +   +++  N ++Q  N  L +   E Q L   L ++QQ    L 
Sbjct: 1832 ENQLRELQARLASVAELESKLQFFNNQIQTLNFSLEQKEKEKQALGQHLVELQQTIEQL- 1890

Query: 881  EKANRTDLAESESTKYQTQ--LRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIES 938
             +A  T +A   + KYQ +   R+ E+  +R+  + QT+   + +  +   ++F  Q E+
Sbjct: 1891 -RAENTQVA---AFKYQVENLSRENEALKQRLVEQQQTIDKLRAEASQFASLKF--QAEN 1944

Query: 939  AIRDKKVLNEKYEKNIEYVTQLEAQLQEY---KNNIENLNMNVEELNKMNLELIDKHVQK 995
              R+ + L ++  +  + V +L A+  ++   +  +ENL    E L K  L    + + +
Sbjct: 1945 LQRENEALKQRLVELQQTVDKLRAEAAQFGSLQYQVENLTRENEAL-KQRLAQTAETLSQ 2003

Query: 996  QQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTT 1055
            Q  Q+ +   +     ++L  L  Q + E    + K+  ++    +   D +  + Q   
Sbjct: 2004 QVAQNSELQRRVQQLESELQLLKMQLEGE--REDNKVKRSRNDKNN--EDLQKVIQQLQQ 2059

Query: 1056 KLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKE-----TKLTFEMNIPKTE 1110
            ++EN+  E+Q   +++ +    +  +QIL  E++D I++L        K   ++     +
Sbjct: 2060 EIENLRREIQARDQKIAELSNASYTIQILQHEKEDLIRKLDAISQVYAKSQTDLQNSLQK 2119

Query: 1111 GMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQE-----------EEEFIQERSVLQE 1159
             +++S+ +E  SD+AN                K QE           + +F QE+   + 
Sbjct: 2120 VVVLSARVE-SSDEANKNLTAQVQILSQSLQNKDQELRNLMIAYQELQVKFGQEQENSRR 2178

Query: 1160 QSAKLNTE-LQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLE-QLNTE-NDNLLST 1216
             S+  +++ +QE      ++  L  EL   +  +   I ++K ++E QL+ E    L + 
Sbjct: 2179 SSSMASSKFIQERVQLEAEINRLKNELAIIEHKHNLTIEEIKRQMEVQLSEELRKQLAAA 2238

Query: 1217 VAELRSSISSAVD--QRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDS 1274
             AE    ++ A++  Q+ +E   + +    Q+E D  K + +L +Q+     + EQ L  
Sbjct: 2239 KAEYERRLNDALNAQQQQYEDDRVKRSKQQQKENDDLKNQLQLTIQM-----QLEQQLAE 2293

Query: 1275 VQSSTQEETNKIVTMEQVTSLQ-NKLQDKEEH-LRNLQE--KYADVINQIEILR----SE 1326
            V++  + E  ++     +   +  +L+D+ +H L N +E  K+ D+I Q+++ +    SE
Sbjct: 2294 VKARMEAERRRLEEENAMLRARVQQLEDQLQHALVNEEEILKFKDLIQQLQMQKLKDISE 2353

Query: 1327 IEDEKVAF-XXXXXXXXXXXXXXXXDLRTENQSYKQMQEQ--SILNI-NEENAQLKKSSX 1382
            ++ +   +                   +TE Q  +   +Q   IL + ++EN +L+ ++ 
Sbjct: 2354 LQQKLEEYRSLHVNAGGSLQDAIKTSFQTEIQQLRDKVQQLNQILEVKSKENNELQSANL 2413

Query: 1383 XXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLV 1442
                        +  + + + + T ++E    ++ Q +++ T     R   +E    +L 
Sbjct: 2414 NLMRERSEIKKSMTSSNSNI-QFTMEIESLKRQLIQ-SNDRTQEYEARIKSYEG---KLN 2468

Query: 1443 EYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLN 1502
            +YE ++  +  E +    IL +K  E  N +  M  + + + + + + L+ + +  V L 
Sbjct: 2469 QYELQLSQVVNELKQTQDILNIKKMERDNAFNQMD-QLKSQTLSMSQALS-QGSNDVDL- 2525

Query: 1503 KQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFAS 1562
            + +  L K + E +     +   L N+    + LN + T  + M ++ S K    ++  +
Sbjct: 2526 QNIVFLKKEI-ENLQNLKHLFIFLNNK----LNLNQKRTVEKEMYKSQSEKNYAELNRKN 2580

Query: 1563 DTKQGRDEQLDNT-----MNKELLDAVPRAELDLAMYMLHQ 1598
            +    + E+L+N       N   + A+ +  ++L  ++L++
Sbjct: 2581 EELVRKIEELNNVKLQYQQNNNKIYALEKEVINLLFFILNK 2621



 Score =  125 bits (301), Expect = 1e-26
 Identities = 253/1329 (19%), Positives = 541/1329 (40%), Gaps = 82/1329 (6%)

Query: 305  EEKTEIEEKGSLEIANMTELTKKIELL-EHLNCQIRQTN-------KELENKLATMGTES 356
            EE+  +EEK       +  L K++E+  +H N +I+Q++       +EL+NK+A   ++ 
Sbjct: 306  EERARMEEKIVQAQTEIMRLEKQVEIWKDHCN-KIQQSHPNQDQRIQELQNKIADYESKI 364

Query: 357  KAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKIN-KNEIAKLEMVIQ 415
              ++  +++ + LI  K       K  S  S +   T +   ++    KN+++  E++I 
Sbjct: 365  NQLAIDNQRLNQLIQIKDEEADKIKRASRQSNVDQRTYDSLQNENYQLKNDLSSKELLIV 424

Query: 416  SLNKDLVDKEYVISEKDTXXXXXXXXXXGK-DTLIAQLQLEHQQHMEGPSLIHV---GTN 471
             LN+ + D E    +              + D + + L+  +Q++ +     +     TN
Sbjct: 425  QLNQRIRDFEGNGQKTTQELTQKIFILTNELDNVTSHLKARNQEYEDLSKRYNQLLQQTN 484

Query: 472  TEDVNEIAKVQEQLKQ--ELNDEIKDVNV--KDLIEKLKSAEEQITQLNDEIDAANKNMI 527
                +   K QEQL +  +L  E++ +    +   +++K    +   L    +     +I
Sbjct: 485  QMTQSGEFKYQEQLSKSIQLGQEVEKLAALTRAQADEIKDWRNKYADLESRYNQ-QIILI 543

Query: 528  KVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVD 587
              ++N ++  +Q+Q   D   + +    E  +    L   +QK  EL+     L+  +  
Sbjct: 544  SQQTNQEVYRRQIQDLEDQLRRKTAEANEWQQSFTNLQ--AQKERELKNLMETLKDEIRK 601

Query: 588  YDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELH-------ILQQKYDEV 640
              S   +++D Y K+ +   L   +++ ++ +  +K + ++ L        + ++K   +
Sbjct: 602  SSSSLNLQND-YNKLKDQVQLLTHQIEQLNKISIEKDNEIRLLRNQAGNDALYREKIINM 660

Query: 641  EDKLADI-SQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDL 699
            E+KL  + S+LQ+    ++IK   +      L  ++   +  IE   +       T++ L
Sbjct: 661  ENKLVQLTSELQNQINLNQIKESEIVSLKRQLEEARGRYSADIETQLIQLRSQVTTLQQL 720

Query: 700  ENDKEDIMNKLQNYIQENMDLTDKLEK-MSAEKISELLAKINHEEQ--SKIQTQFGIDAK 756
               K++I+N LQ  + E+ D   + +K    +++   + ++  + Q  +K+  +  +   
Sbjct: 721  LQQKDEIINDLQRKLAEHEDPVKRSKKDNETQRLLNQIQELTFDNQRLTKLNNEQAVTID 780

Query: 757  IQERDLY-IENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSE 815
               RDL  ++     + +   +I  L   I V+E +  ++  + D L   L E +    +
Sbjct: 781  QLRRDLINLQQQSQNVVEQNRKIEALLYQIEVLEKQLRAVAEERDNLKRQLLETETLRQK 840

Query: 816  YTIQEDELVNRLAVLMDHDRVVEKQLLEIEHEN-KELQKKNQILLEENQNLQIS-LSDMQ 873
               QE     R   L +  R +  QL   + EN K   K++QI     Q ++I+ L ++ 
Sbjct: 841  LKEQE----ARELYLQEQIRNLVAQLENAQTENVKRAGKESQI---NQQQVRINELENLI 893

Query: 874  QHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFN 933
            Q     +EK N     + +      +  + +S +     + +  I+    EI+ L     
Sbjct: 894  QVLRGEIEKLNNIIRMKDQDLDSLKRESNRKSVVDAEKQQLENKILLLASEIDRLSRSLQ 953

Query: 934  TQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNL-ELIDKH 992
             + E   R K ++ EK +  ++ + QL++++   ++    LN  ++ L + N+ +L D++
Sbjct: 954  DKHEEVNRLKSIIIEK-DSQLQSLPQLQSRIALLQDENNRLNAQIKLLTEENIRKLTDEN 1012

Query: 993  VQKQQ--TQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDY---E 1047
            +Q +Q   +  D+  Q     NK+  L+ ++ E +  +   +   ++S  + ++DY   +
Sbjct: 1013 IQLRQRLNEMADFERQKNELENKIQLLISER-ERLNGIITTMTQEKLSLQAQLNDYAQGD 1071

Query: 1048 SKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIP 1107
                +   ++E+++ + QR+ + L +    N EL+  +++  D  +   E  L  ++N+ 
Sbjct: 1072 RIRKELEYQIESLKRDKQRLEEGLTNLANENNELRSRLQQLGDMDRVRGE--LENKINLL 1129

Query: 1108 KTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTE 1167
              E   + + +   +++ N               L+   E        +  E++ +LN  
Sbjct: 1130 IQENDRLRAALAAKNEE-NTKLILKINDLSNLEKLRADLEGRI----KIYGEENQRLNDI 1184

Query: 1168 LQECYTKIIQLETLNTELTGHDVVNQEQIN-QLKSKLEQLNTENDNLLSTVAELRSSISS 1226
            ++        L+T   +L+     N EQ+   L+ ++  L  EN  L   V      +  
Sbjct: 1185 IRRLTEDNTSLQTRIAQLS-----NIEQVRITLEGQINLLVAENKRLNDLVRAKDEELVQ 1239

Query: 1227 AVD-QRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNK 1285
              D +  FE+ +L       R          +  Q     +K  QL   ++ +T E  N+
Sbjct: 1240 IRDIKTRFELFQLRNIDALARLTITMAELERVSAQSVEKTNKIIQLEQRLRDNTLEYQNQ 1299

Query: 1286 IVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIE--DEKVAFXXXXXXXXX 1343
             +  ++V  L  +++     L N + +   V  + + L  E +  D + A          
Sbjct: 1300 AL-QQKVNLLTEQIERLVRELENARNELIQVSRKCQSLEIEKQTWDAQRAQYEQTIAQLH 1358

Query: 1344 XXXXXXXDLRTENQSY---KQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEA 1400
                   +   E +     KQ Q+  +  +  EN  L+               +V+    
Sbjct: 1359 AEIQRLREQADEGEKVKRSKQNQDNRVAQLEAENKYLQDQLEKLRNDNNQLLQQVSQLTL 1418

Query: 1401 KVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELA 1460
             + +L  Q +L D+ +  +  E    L  +  E E V Q+L    + I +LT E      
Sbjct: 1419 TLQQL--QAKLNDNTLQIQNQELQNRLNAKTAELERVAQELQRLSQLINELTLE------ 1470

Query: 1461 ILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTN 1520
            + RLK  ENA  +E  ++  E    +L   L +   E   LN+   EL+  L    A  N
Sbjct: 1471 VNRLK-SENAG-FEVTKRALEGRIQELASRLEMLTGEINRLNQLNGELSYKLSSS-ATIN 1527

Query: 1521 EMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKEL 1580
            E    L +  +    L++ ++   + +    ++  +H   A    Q  +  +      E 
Sbjct: 1528 ERYARLSDAYVLQCALSESLSKKVSDLIGFQNEADEHRKRAQRQSQDNEALIQRINQLEQ 1587

Query: 1581 LDAVPRAEL 1589
            L A    EL
Sbjct: 1588 LLAEKDREL 1596



 Score =  118 bits (283), Expect = 2e-24
 Identities = 235/1202 (19%), Positives = 515/1202 (42%), Gaps = 118/1202 (9%)

Query: 476  NEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNH-- 533
            N +A+++    + +    K+  +     ++   E  I  L  EI+  N N+I++K     
Sbjct: 857  NLVAQLENAQTENVKRAGKESQINQQQVRINELENLIQVLRGEIEKLN-NIIRMKDQDLD 915

Query: 534  KLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSG-- 591
             LK +  +K++ +  K    NK I+ L  E+  LS+ + +  EE   L+  +++ DS   
Sbjct: 916  SLKRESNRKSVVDAEKQQLENK-ILLLASEIDRLSRSLQDKHEEVNRLKSIIIEKDSQLQ 974

Query: 592  ---------RMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVED 642
                      +++ +  +   +++ L E  ++ ++    Q    + E+   +++ +E+E+
Sbjct: 975  SLPQLQSRIALLQDENNRLNAQIKLLTEENIRKLTDENIQLRQRLNEMADFERQKNELEN 1034

Query: 643  KL----ADISQLQSDQVCSEIKSVHLEEQIDALSAS---KKELALVIENLKLDKEQLYGT 695
            K+    ++  +L         + + L+ Q++  +     +KEL   IE+LK DK++L   
Sbjct: 1035 KIQLLISERERLNGIITTMTQEKLSLQAQLNDYAQGDRIRKELEYQIESLKRDKQRLEEG 1094

Query: 696  IKDLENDKEDIMNKLQ---NYIQENMDLTDKLEKMSAE--KISELLAKINHEEQSKIQTQ 750
            + +L N+  ++ ++LQ   +  +   +L +K+  +  E  ++   LA  N EE +K+  +
Sbjct: 1095 LTNLANENNELRSRLQQLGDMDRVRGELENKINLLIQENDRLRAALAAKN-EENTKLILK 1153

Query: 751  FGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEK- 809
                  +   +    ++E  +  Y     RL + I  + +   SL+ +  QL +  Q + 
Sbjct: 1154 IN---DLSNLEKLRADLEGRIKIYGEENQRLNDIIRRLTEDNTSLQTRIAQLSNIEQVRI 1210

Query: 810  -QKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQIS 868
              +      + E++ +N L    D + V   Q+ +I+   +  Q +N   ++    L I+
Sbjct: 1211 TLEGQINLLVAENKRLNDLVRAKDEELV---QIRDIKTRFELFQLRN---IDALARLTIT 1264

Query: 869  LSDMQQHYNALVEKANRTDLAE----SESTKYQTQLRDLESNLKRITHEHQTLIVQKKKE 924
            ++++++     VEK N+    E      + +YQ Q   L+  +  +T + + L+ + +  
Sbjct: 1265 MAELERVSAQSVEKTNKIIQLEQRLRDNTLEYQNQA--LQQKVNLLTEQIERLVRELENA 1322

Query: 925  IEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNI-ENLNMNVEELNK 983
              +L I+ + + +S   +K+  + +  +  + + QL A++Q  +    E   +   + N+
Sbjct: 1323 RNEL-IQVSRKCQSLEIEKQTWDAQRAQYEQTIAQLHAEIQRLREQADEGEKVKRSKQNQ 1381

Query: 984  MN----LELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSY 1039
             N    LE  +K++Q Q  +  +   Q + ++++L   L+Q       L  K+N+  +  
Sbjct: 1382 DNRVAQLEAENKYLQDQLEKLRNDNNQLLQQVSQLTLTLQQ-------LQAKLNDNTLQI 1434

Query: 1040 MSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDS--------KQHNEELQILVREQDDQ 1091
             +   + +++L   T +LE + +E+QR+S QL++         K  N   ++  R  + +
Sbjct: 1435 QN--QELQNRLNAKTAELERVAQELQRLS-QLINELTLEVNRLKSENAGFEVTKRALEGR 1491

Query: 1092 IKEL--KETKLTFEMN-IPKTEGMI---ISSTIEPMSDDANNVDXXXXX-XXXXXXXLKV 1144
            I+EL  +   LT E+N + +  G +   +SS+       A   D              KV
Sbjct: 1492 IQELASRLEMLTGEINRLNQLNGELSYKLSSSATINERYARLSDAYVLQCALSESLSKKV 1551

Query: 1145 QEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETL----NTELTGHDVVNQEQINQLK 1200
             +   F  E    ++++ + + + +    +I QLE L    + EL    V +Q  ++ L+
Sbjct: 1552 SDLIGFQNEADEHRKRAQRQSQDNEALIQRINQLEQLLAEKDRELQNLKVASQ-NVSILQ 1610

Query: 1201 SKLEQLNTENDNLLSTVAELRS-------------SISSAVDQRGFEIAELWKQ--HLAQ 1245
             +L+Q N + +NL+  + EL +             + +S V+    +I +   Q   L +
Sbjct: 1611 MQLQQSNQDKENLIKRIRELENILGERDKEIAGLRNANSQVNLLQIQIQQYENQINDLKR 1670

Query: 1246 READ-FQKTEHELR-VQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVT-SLQNKLQDK 1302
            R AD  +  + +   ++ S    +  +L        QE   +I   + ++   +N+L+ +
Sbjct: 1671 RHADELENVKRQYEGLRQSTVNREINELTVKFNIRIQELEREIQKYKSLSEQYENELRAQ 1730

Query: 1303 EEHLRNLQEKYADVINQI-----EILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTE-- 1355
             +    L ++  D  N+      ++ RS    ++V                  +L  E  
Sbjct: 1731 RQQNSELLQRLVDAENRARDSDEQVKRSRAGQQQVNNLEENLRFVTAELEKQKNLLAEEK 1790

Query: 1356 NQSYKQMQEQSIL--NINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKD 1413
            N++ +   ++SIL   I   N  LK+                N        L    EL+ 
Sbjct: 1791 NKNAQLESQKSILAMEIERLNTILKEKLILIEDFQRREAEYENQLRELQARLASVAELES 1850

Query: 1414 SEIYQKTHEYTI--TLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENAN 1471
               +      T+  +L Q+  E + + Q LVE ++ IE L  E  +++A  + ++ EN +
Sbjct: 1851 KLQFFNNQIQTLNFSLEQKEKEKQALGQHLVELQQTIEQLRAE-NTQVAAFKYQV-ENLS 1908

Query: 1472 HYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEI 1531
                  K+  +E+ + I++L  + ++  SL  Q   L +  E    +  E+Q  ++    
Sbjct: 1909 RENEALKQRLVEQQQTIDKLRAEASQFASLKFQAENLQRENEALKQRLVELQQTVDKLRA 1968

Query: 1532 EIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDL 1591
            E          ++N+ R + +  Q+     + T +   +Q+    N EL   V + E +L
Sbjct: 1969 EAAQFGSLQYQVENLTRENEALKQR----LAQTAETLSQQV--AQNSELQRRVQQLESEL 2022

Query: 1592 AM 1593
             +
Sbjct: 2023 QL 2024



 Score =   99 bits (238), Expect = 5e-19
 Identities = 187/1071 (17%), Positives = 429/1071 (40%), Gaps = 86/1071 (8%)

Query: 144  VTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXX 203
            +  L   + EKD  L  L+V  + +    + LQ+   +K+ +I+   +            
Sbjct: 1582 INQLEQLLAEKDRELQNLKVASQNVSILQMQLQQSNQDKENLIKRIRELEN-----ILGE 1636

Query: 204  XXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEA--NKLLE 261
                     +   Q+  +Q      E +  D K+R   ++E+   +   L ++  N+ + 
Sbjct: 1637 RDKEIAGLRNANSQVNLLQIQIQQYENQINDLKRRHADELENVKRQYEGLRQSTVNREIN 1696

Query: 262  AARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANM 321
                + ++   +L +E+++                +Q+ E   +   + E +       +
Sbjct: 1697 ELTVKFNIRIQELEREIQKYKSLSEQYENELRAQRQQNSE-LLQRLVDAENRARDSDEQV 1755

Query: 322  TELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASK 381
                   + + +L   +R    ELE +   +  E    +    + S L       NT  K
Sbjct: 1756 KRSRAGQQQVNNLEENLRFVTAELEKQKNLLAEEKNKNAQLESQKSILAMEIERLNTILK 1815

Query: 382  MK----SPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXX 437
             K      + +  +E  NQ  + +     +A+LE  +Q  N  +    + + +K+     
Sbjct: 1816 EKLILIEDFQRREAEYENQLRELQARLASVAELESKLQFFNNQIQTLNFSLEQKEKEKQA 1875

Query: 438  XXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVN 497
                       I QL+ E+ Q         V      V  +++  E LKQ L      V 
Sbjct: 1876 LGQHLVELQQTIEQLRAENTQ---------VAAFKYQVENLSRENEALKQRL------VE 1920

Query: 498  VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNF----SKVSDS 553
             +  I+KL++   Q   L  + +    N+ +     K +L ++Q+T+D      ++    
Sbjct: 1921 QQQTIDKLRAEASQFASLKFQAE----NLQRENEALKQRLVELQQTVDKLRAEAAQFGSL 1976

Query: 554  NKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSG-RMIESDVYKKMIEMENLAETR 612
              ++  LT E   L Q++A+  E          +     + +ES++    +++E   E  
Sbjct: 1977 QYQVENLTRENEALKQRLAQTAETLSQQVAQNSELQRRVQQLESELQLLKMQLEGEREDN 2036

Query: 613  LKAISLLESQKFDLVQELHILQQKYDEV-------EDKLADISQLQSDQVCSEIKSVHLE 665
                S  +    DL + +  LQQ+ + +       + K+A++S         + +   L 
Sbjct: 2037 KVKRSRNDKNNEDLQKVIQQLQQEIENLRREIQARDQKIAELSNASYTIQILQHEKEDLI 2096

Query: 666  EQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLE 725
             ++DA+S    +    ++N       L   ++  +   +++  ++Q   Q   +   +L 
Sbjct: 2097 RKLDAISQVYAKSQTDLQNSLQKVVVLSARVESSDEANKNLTAQVQILSQSLQNKDQELR 2156

Query: 726  KMSAEKISELLAKINHEEQSKIQTQFGIDAK-IQERDLYIENIESELSKYKSRICRLE-- 782
             +      EL  K   E+++  ++     +K IQER      +E+E+++ K+ +  +E  
Sbjct: 2157 NLMI-AYQELQVKFGQEQENSRRSSSMASSKFIQER----VQLEAEINRLKNELAIIEHK 2211

Query: 783  ESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLL 842
             ++ + E +R    + +++L   L     A +EY  + ++ +N      + DRV  K+  
Sbjct: 2212 HNLTIEEIKRQMEVQLSEELRKQL---AAAKAEYERRLNDALNAQQQQYEDDRV--KRSK 2266

Query: 843  EIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRD 902
            + + EN +L  KNQ+ L     +Q+ L        A +E   R    E E+   + +++ 
Sbjct: 2267 QQQKENDDL--KNQLQL----TIQMQLEQQLAEVKARMEAERRR--LEEENAMLRARVQQ 2318

Query: 903  LESNLKRITHEHQTLIVQKK--KEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIE--YVT 958
            LE  L+      + ++  K   ++++  +++  ++++  + + + L+     +++    T
Sbjct: 2319 LEDQLQHALVNEEEILKFKDLIQQLQMQKLKDISELQQKLEEYRSLHVNAGGSLQDAIKT 2378

Query: 959  QLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALL 1018
              + ++Q+ ++ ++ LN  +E  +K N EL   ++   + +S     +    +   N+ +
Sbjct: 2379 SFQTEIQQLRDKVQQLNQILEVKSKENNELQSANLNLMRERS-----EIKKSMTSSNSNI 2433

Query: 1019 KQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHN 1078
             Q   EI +L +++    +       +YE+++  +  KL   E ++ +V  +L   KQ  
Sbjct: 2434 -QFTMEIESLKRQL----IQSNDRTQEYEARIKSYEGKLNQYELQLSQVVNEL---KQTQ 2485

Query: 1079 EELQILVREQD---DQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXX 1135
            + L I   E+D   +Q+ +LK   L+    + +    +    I  +  +  N+       
Sbjct: 2486 DILNIKKMERDNAFNQMDQLKSQTLSMSQALSQGSNDVDLQNIVFLKKEIENLQNLKHLF 2545

Query: 1136 XXXXXXLKVQEEEEFIQE--RSVLQEQSAKLNTELQECYTKIIQLETLNTE 1184
                  L + ++    +E  +S  ++  A+LN + +E   KI +L  +  +
Sbjct: 2546 IFLNNKLNLNQKRTVEKEMYKSQSEKNYAELNRKNEELVRKIEELNNVKLQ 2596



 Score = 97.1 bits (231), Expect = 4e-18
 Identities = 199/1033 (19%), Positives = 447/1033 (43%), Gaps = 102/1033 (9%)

Query: 547  FSKVSDSNKEIVRLTEELH-HLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEM 605
            F  V +  ++  R+ +E +  + Q   +L + + N++      + G   E+DV + + ++
Sbjct: 92   FRDVDEITEQFNRILKEKNDQIDQLKRQLNDPEENVKRAA---NRGGPSENDVSELIQQL 148

Query: 606  ENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEI--KSVH 663
            +NL       + L +S++ ++   L  + Q Y+   +KL+D + L+  Q   E+  ++ +
Sbjct: 149  QNLN------VELTKSRQNEI--RLSAMVQNYENQINKLSD-ANLKLSQELKEVGEQNQY 199

Query: 664  LEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQ-ENMDLTD 722
            L  Q+   +   +   + I++ + +  +L+  +++ + + E   N   N ++ +N +L +
Sbjct: 200  LVSQLQGQNPESRIREIQIKHAE-ELNKLHAQLREAQLNAERNQNDQINQLRKQNQELVN 258

Query: 723  KLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLE 782
            ++E++++     L+  +  E  +K  T   ++  IQ+R+  ++N +++ +       R+E
Sbjct: 259  EIERLTS-----LIKTLQQELSAKGDTT-QLNIIIQQRNQELDNWKNKYNLLAEERARME 312

Query: 783  ESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLL 842
            E I   +     LE++ +    +  + Q+++     +  EL N++A   D+    E ++ 
Sbjct: 313  EKIVQAQTEIMRLEKQVEIWKDHCNKIQQSHPNQDQRIQELQNKIA---DY----ESKIN 365

Query: 843  EIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRD 902
            ++  +N+ L +  QI  EE                   +K  R     +   +    L++
Sbjct: 366  QLAIDNQRLNQLIQIKDEE------------------ADKIKRASRQSNVDQRTYDSLQN 407

Query: 903  LESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEA 962
                LK      + LIVQ  + I D E       +   +   +L  + + N+   + L+A
Sbjct: 408  ENYQLKNDLSSKELLIVQLNQRIRDFEGNGQKTTQELTQKIFILTNELD-NV--TSHLKA 464

Query: 963  QLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKD 1022
            + QEY++  +  N  +++ N+M      K+ Q+Q ++S     Q   E+ KL AL + + 
Sbjct: 465  RNQEYEDLSKRYNQLLQQTNQMTQSGEFKY-QEQLSKS----IQLGQEVEKLAALTRAQA 519

Query: 1023 EEIIALNQKINNAQVSYMSMVSDYESKLAQ--FTTKLENMEEEMQRVSKQLLDSKQHNEE 1080
            +EI     K  + +  Y   +     +  Q  +  +++++E++++R       + + NE 
Sbjct: 520  DEIKDWRNKYADLESRYNQQIILISQQTNQEVYRRQIQDLEDQLRR------KTAEANEW 573

Query: 1081 LQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXX 1140
             Q     Q  + +ELK    T +  I K+     SS++   +D     D           
Sbjct: 574  QQSFTNLQAQKERELKNLMETLKDEIRKS-----SSSLNLQNDYNKLKDQVQLLTHQIEQ 628

Query: 1141 XLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLK 1200
              K+  E++   E  +L+ Q+   N  L     KII +E    +LT  ++ NQ  +NQ+K
Sbjct: 629  LNKISIEKD--NEIRLLRNQAG--NDALYR--EKIINMENKLVQLTS-ELQNQINLNQIK 681

Query: 1201 SKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREA---DFQK--TEH 1255
                ++ +    L        + I + + Q   ++  L +Q L Q++    D Q+   EH
Sbjct: 682  E--SEIVSLKRQLEEARGRYSADIETQLIQLRSQVTTL-QQLLQQKDEIINDLQRKLAEH 738

Query: 1256 ELRVQLSAFESKYEQLLDSVQSSTQE-------ETNKIVTMEQVTSLQNKLQDKEEHLRN 1308
            E  V+ S  +++ ++LL+ +Q  T +          + VT++Q+      LQ + +++  
Sbjct: 739  EDPVKRSKKDNETQRLLNQIQELTFDNQRLTKLNNEQAVTIDQLRRDLINLQQQSQNVVE 798

Query: 1309 LQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSIL 1368
               K   ++ QIE+L  ++    VA                     E ++ +   ++ I 
Sbjct: 799  QNRKIEALLYQIEVLEKQL--RAVAEERDNLKRQLLETETLRQKLKEQEARELYLQEQIR 856

Query: 1369 NI--NEENAQLKK-SSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTI 1425
            N+    ENAQ +                R+N+ E  +  L  ++E  ++ I  K  +   
Sbjct: 857  NLVAQLENAQTENVKRAGKESQINQQQVRINELENLIQVLRGEIEKLNNIIRMKDQDLD- 915

Query: 1426 TLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYET--MQKESEIE 1483
            +L + ++    V  +  + E +I  L  E +     L+ K HE  N  ++  ++K+S+++
Sbjct: 916  SLKRESNRKSVVDAEKQQLENKILLLASEIDRLSRSLQDK-HEEVNRLKSIIIEKDSQLQ 974

Query: 1484 RVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNL 1543
             +  ++   + + +  + N+  A++    EE + K  +    L  +  E+     +   L
Sbjct: 975  SLPQLQS-RIALLQDEN-NRLNAQIKLLTEENIRKLTDENIQLRQRLNEMADFERQKNEL 1032

Query: 1544 QNMVRASSSKIQK 1556
            +N ++   S+ ++
Sbjct: 1033 ENKIQLLISERER 1045



 Score = 61.3 bits (142), Expect = 2e-07
 Identities = 102/518 (19%), Positives = 212/518 (40%), Gaps = 35/518 (6%)

Query: 1052 QFTTKL-ENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTE 1110
            +FTTK  +N+    QR   + +D  +  E+   +++E++DQI +LK      E N+ +  
Sbjct: 74   RFTTKKKQNLSVSPQRGGFRDVD--EITEQFNRILKEKNDQIDQLKRQLNDPEENVKRAA 131

Query: 1111 ---GMIISSTIEPMSDDAN-NVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNT 1166
               G   +   E +    N NV+              VQ  E  I +   L + + KL+ 
Sbjct: 132  NRGGPSENDVSELIQQLQNLNVELTKSRQNEIRLSAMVQNYENQINK---LSDANLKLSQ 188

Query: 1167 ELQECYTK----IIQLETLNTE--LTGHDVVNQEQINQLKSKLE--QLNTENDNLLSTVA 1218
            EL+E   +    + QL+  N E  +    + + E++N+L ++L   QLN E  N    + 
Sbjct: 189  ELKEVGEQNQYLVSQLQGQNPESRIREIQIKHAEELNKLHAQLREAQLNAER-NQNDQIN 247

Query: 1219 ELRSSISSAVDQ--RGFEIAELWKQHLAQREADFQKTE--HELRVQLSAFESKYEQLLDS 1274
            +LR      V++  R   + +  +Q L+ +    Q      +   +L  +++KY  L + 
Sbjct: 248  QLRKQNQELVNEIERLTSLIKTLQQELSAKGDTTQLNIIIQQRNQELDNWKNKYNLLAE- 306

Query: 1275 VQSSTQEETNKIVTME-QVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIED---- 1329
             + +  EE  KIV  + ++  L+ +++  ++H   +Q+ + +   +I+ L+++I D    
Sbjct: 307  -ERARMEE--KIVQAQTEIMRLEKQVEIWKDHCNKIQQSHPNQDQRIQELQNKIADYESK 363

Query: 1330 -EKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXX 1388
              ++A                 D          + +++  ++  EN QLK          
Sbjct: 364  INQLAIDNQRLNQLIQIKDEEADKIKRASRQSNVDQRTYDSLQNENYQLKNDLSSKELLI 423

Query: 1389 XXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRI 1448
                 R+ D E    + T +L  K   +  +    T  L  RN E+E++ ++  +  ++ 
Sbjct: 424  VQLNQRIRDFEGNGQKTTQELTQKIFILTNELDNVTSHLKARNQEYEDLSKRYNQLLQQT 483

Query: 1449 EDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAEL 1508
              +T   E +      K  +     E +   +  +  ++ +  N         N+Q+  +
Sbjct: 484  NQMTQSGEFKYQEQLSKSIQLGQEVEKLAALTRAQADEIKDWRNKYADLESRYNQQIILI 543

Query: 1509 NKALEEEV--AKTNEMQTALENQEIEIVTLNDEITNLQ 1544
            ++   +EV   +  +++  L  +  E        TNLQ
Sbjct: 544  SQQTNQEVYRRQIQDLEDQLRRKTAEANEWQQSFTNLQ 581



 Score = 37.9 bits (84), Expect = 2.3
 Identities = 58/245 (23%), Positives = 103/245 (42%), Gaps = 21/245 (8%)

Query: 140  QLGDVTHLSNTIKEKD----NALSVLQVKMKI-METTILDLQEKINEKDQIIEAKNKATT 194
            +L D++ L   ++E      NA   LQ  +K   +T I  L++K+ + +QI+E K+K   
Sbjct: 2347 KLKDISELQQKLEEYRSLHVNAGGSLQDAIKTSFQTEIQQLRDKVQQLNQILEVKSKENN 2406

Query: 195  XXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLE 254
                              + K+ MT    N I    E +  K++L   I+S D R    E
Sbjct: 2407 ----ELQSANLNLMRERSEIKKSMTSSNSN-IQFTMEIESLKRQL---IQSND-RTQEYE 2457

Query: 255  EANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQ--SIEPSCEEKTEIEE 312
               K  E    +  L+ S++  EL+Q                 Q   ++      ++   
Sbjct: 2458 ARIKSYEGKLNQYELQLSQVVNELKQTQDILNIKKMERDNAFNQMDQLKSQTLSMSQALS 2517

Query: 313  KGS--LEIANMTELTKKIELLEHLNCQIRQTNKELE-NKLATMGTESKAVSSPSKKGSPL 369
            +GS  +++ N+  L K+IE L++L       N +L  N+  T+  E +   S S+K    
Sbjct: 2518 QGSNDVDLQNIVFLKKEIENLQNLKHLFIFLNNKLNLNQKRTV--EKEMYKSQSEKNYAE 2575

Query: 370  ISRKS 374
            ++RK+
Sbjct: 2576 LNRKN 2580


>UniRef50_O42263 Cluster: Kinesin-related protein; n=2; Xenopus|Rep:
            Kinesin-related protein - Xenopus laevis (African clawed
            frog)
          Length = 2954

 Score =  125 bits (302), Expect = 9e-27
 Identities = 234/1120 (20%), Positives = 482/1120 (43%), Gaps = 136/1120 (12%)

Query: 500  DLIEKLKSA-EEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIV 558
            D+ E  K++ E++IT L  ++ +  +   ++  + +LK+ ++++ +     V   N E+V
Sbjct: 542  DMAECRKASFEKEITSLQQQLQSKEEEKKELVQSFELKIAELEEQL----SVKAKNLEMV 597

Query: 559  RLTEELHHLSQKV-AELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAI- 616
              + E H ++ +V  ++E+E    ++ ++         SD+    ++ + L+ +  + I 
Sbjct: 598  TNSRE-HSINAEVQTDVEKEVVRKEMSVLGDSGYNASNSDLQDSSVDGKRLSSSHDECIE 656

Query: 617  --SLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSAS 674
               +LE +  DL + +  L +K +  + K ++   ++S Q+C  I    + E+ +AL   
Sbjct: 657  HRKMLEQKIVDLEEFIENLNKKSENDKQKSSEQDFMESIQLCEAI----MAEKANAL--- 709

Query: 675  KKELALV---IENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEK 731
             +ELAL+    +N+ L+ E L   I DLE             ++EN + T++ E +  E 
Sbjct: 710  -EELALMRDNFDNIILENETLKREIADLERS-----------LKENQE-TNEFEILEKET 756

Query: 732  ISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDR 791
              E  A++ HE  S       +   ++  ++Y +N+E +L + K+++ + E+ I + E  
Sbjct: 757  QKEHEAQLIHEIGS-------LKKLVENAEMYNQNLEEDL-ETKTKLLK-EQEIQLAE-- 805

Query: 792  RYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKEL 851
               L ++AD     LQ+K + +       D        L +    +++ L + E   ++ 
Sbjct: 806  ---LRKRADN----LQKKVRNFDLSVSMGDS-----EKLCEEIFQLKQSLSDAEAVTRDA 853

Query: 852  QKKNQILLEENQNLQISLSDMQQHYNALVEKANRTD-LAESESTKYQTQLRDLESNLKRI 910
            QK+   L  EN  L+  + D    YN   + A+  +   E+E + Y+    DL+  L+  
Sbjct: 854  QKECSFLRSENLELKEKMEDTSNWYNQKEKAASLFEKQLETEKSNYKKMEADLQKELQSA 913

Query: 911  THEHQTL----------IVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQL 960
             +E   L           +  + E+E    EF+ Q+E A+ +K  L  +     EY   L
Sbjct: 914  FNEINYLNGLLAGKVPRDLLSRVELEKKVSEFSKQLEKALEEKNALENEVTCLSEY-KFL 972

Query: 961  EAQLQEYKNNIENLN---MNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNAL 1017
              +++  KN I   +   M +++  + +  +I K     Q QS +   Q  +E+    + 
Sbjct: 973  PNEVECLKNQISKASEEIMLLKQEGEHSASIISKQEIIMQEQS-EQILQLTDEVTHTQSK 1031

Query: 1018 LKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQH 1077
            ++Q +E+ + + +  ++    Y+   S+ E  L +    +EN++  M+ V  ++ D+K  
Sbjct: 1032 VQQTEEQYLEMKKMHDDLFEKYIRNKSEAEDLLRE----MENLKGTMESVEVKIADTK-- 1085

Query: 1078 NEELQILVREQDDQIKELK---ETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXX 1134
              EL+  +R+++  + E K   +   T     P ++ +  S  +E  S D   ++     
Sbjct: 1086 -HELEETIRDKEQLLHEKKYFFQAMQTIFPITPLSDSLPPSKLVEGNSQDPIEINDYHNL 1144

Query: 1135 XXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTE---------- 1184
                     +    E   ER+ L+EQ   LNT+LQ    + I+   L             
Sbjct: 1145 IALATERNNIMVCLE--TERNSLKEQVIDLNTQLQSLQAQSIEKSDLQKPKQDLEEGEVK 1202

Query: 1185 -------LTGHDVVNQEQINQLK-------SKLEQLNTENDNLLSTVAELRSS---ISSA 1227
                   L GH   +Q  I +L+        KL+ L  E  N+     EL+++   + + 
Sbjct: 1203 LLLEMELLKGHLTDSQLSIEKLQLENLEVTEKLQTLQEEMKNITIERNELQTNFEDLKAE 1262

Query: 1228 VDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLD-SVQSSTQEE---- 1282
             D    +++E  +Q + + + + +  + ELR Q    +S  +QLLD SV  S+       
Sbjct: 1263 HDSLKQDLSENIEQSI-ETQDELRAAQEELREQKQLVDSFRQQLLDCSVGISSPNHDAVA 1321

Query: 1283 TNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRS---EIEDEKVAFXXXXX 1339
              + V++ +V SLQ+++   E     LQ     +++++E+LR+    +E E +       
Sbjct: 1322 NQEKVSLGEVNSLQSEMLRGERD--ELQTSCKALVSELELLRAHVKSVEGENLEITKKLN 1379

Query: 1340 XXXXXXXXXXXDLRTENQSYKQMQE-QSILNINEENAQLKKSSXXXXXXXXXXXXRVNDA 1398
                       +        + ++E  + L    E    K++              V++ 
Sbjct: 1380 GLEKEILGKSEESEVLKSMLENLKEDNNKLKEQAEEYSSKENQFSLEEVFSGSQKLVDEI 1439

Query: 1399 E---AKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEK 1455
            E   A++     +LE+KD + ++        L +   + E   Q   ++E+   D   E 
Sbjct: 1440 EVLKAQLKAAEERLEIKDRDYFELVQTANTNLVE--GKLETPLQ--ADHEEDSIDRRSE- 1494

Query: 1456 ESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAE-LNKALEE 1514
            E E+ +L  K+  N    E +Q+E ++E    +E L  ++  SV L   + + L   L E
Sbjct: 1495 EMEIKVLGEKLERNQYLLERLQEE-KLELSNKLEILQKEMETSVLLKDDLQQKLESLLSE 1553

Query: 1515 EVAKTNEMQTALENQ---EIEIVTLNDEITNLQNMVRASS 1551
             +     + T L++    + ++     E+   +N+  A+S
Sbjct: 1554 NIILKENIDTTLKHHSDTQAQLQKTQQELQLAKNLAIAAS 1593



 Score =  112 bits (270), Expect = 7e-23
 Identities = 254/1355 (18%), Positives = 560/1355 (41%), Gaps = 126/1355 (9%)

Query: 213  DTKQQMTKMQEN--FIAMEAEW-KDEKQRLLKDIESKDVRISSLEEANKLLEA---ARFE 266
            D ++ + + QE   F  +E E  K+ + +L+ +I S    + + E  N+ LE     + +
Sbjct: 735  DLERSLKENQETNEFEILEKETQKEHEAQLIHEIGSLKKLVENAEMYNQNLEEDLETKTK 794

Query: 267  ISLEHS-KLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELT 325
            +  E   +LA+  ++              ++    E  CEE  ++++  S   A   +  
Sbjct: 795  LLKEQEIQLAELRKRADNLQKKVRNFDLSVSMGDSEKLCEEIFQLKQSLSDAEAVTRDAQ 854

Query: 326  KKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLIS--RKSGRNTASKMK 383
            K+   L   N ++++  ++  N       + KA S   K+     S  +K   +   +++
Sbjct: 855  KECSFLRSENLELKEKMEDTSN---WYNQKEKAASLFEKQLETEKSNYKKMEADLQKELQ 911

Query: 384  SPWSQLSSETLNQDTDKKINKNEIAKLEMV--IQSLNKDLVDKEYVISEKDTXXXXXXXX 441
            S +++++   LN     K+ ++ ++++E+   +   +K L   E  + EK+         
Sbjct: 912  SAFNEINY--LNGLLAGKVPRDLLSRVELEKKVSEFSKQL---EKALEEKNALENEVTCL 966

Query: 442  XXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVN--VK 499
               K        L++Q       ++ +    E    I   QE + QE +++I  +   V 
Sbjct: 967  SEYKFLPNEVECLKNQISKASEEIMLLKQEGEHSASIISKQEIIMQEQSEQILQLTDEVT 1026

Query: 500  DLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQK---TIDNFS-KVSDSNK 555
                K++  EEQ  ++    D   +  I+ KS  +  L++M+    T+++   K++D+  
Sbjct: 1027 HTQSKVQQTEEQYLEMKKMHDDLFEKYIRNKSEAEDLLREMENLKGTMESVEVKIADTKH 1086

Query: 556  EI---VRLTEELHH-------LSQKVAELEEEKGNLQ-LHLVDYDSGRMIESDVYKKMIE 604
            E+   +R  E+L H         Q +  +     +L    LV+ +S   IE + Y  +I 
Sbjct: 1087 ELEETIRDKEQLLHEKKYFFQAMQTIFPITPLSDSLPPSKLVEGNSQDPIEINDYHNLIA 1146

Query: 605  MENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHL 664
               LA  R   +  LE+++  L +++  L  +   ++ +  + S LQ  +   E   V L
Sbjct: 1147 ---LATERNNIMVCLETERNSLKEQVIDLNTQLQSLQAQSIEKSDLQKPKQDLEEGEVKL 1203

Query: 665  EEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKL 724
              +++ L     +  L IE L+L+  ++   ++ L+ + ++I       I+ N +L    
Sbjct: 1204 LLEMELLKGHLTDSQLSIEKLQLENLEVTEKLQTLQEEMKNIT------IERN-ELQTNF 1256

Query: 725  EKMSAEKISELLAKINHEEQSKIQTQFGIDA---KIQERDLYIENIESELSKYKSRICRL 781
            E + AE  S L   ++   +  I+TQ  + A   +++E+   +++   +L      I   
Sbjct: 1257 EDLKAEHDS-LKQDLSENIEQSIETQDELRAAQEELREQKQLVDSFRQQLLDCSVGISSP 1315

Query: 782  EESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQL 841
                AV    + SL  + + L S +   ++   E       LV+ L +L  H + VE + 
Sbjct: 1316 NHD-AVANQEKVSLG-EVNSLQSEMLRGER--DELQTSCKALVSELELLRAHVKSVEGEN 1371

Query: 842  LEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLR 901
            LEI  +   L+K+     EE++ L+  L ++++  N L E+A      E  S + Q  L 
Sbjct: 1372 LEITKKLNGLEKEILGKSEESEVLKSMLENLKEDNNKLKEQAE-----EYSSKENQFSLE 1426

Query: 902  DLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLE 961
            ++ S  +++  E + L  Q K   E LEI+     E     +       E  +E  T L+
Sbjct: 1427 EVFSGSQKLVDEIEVLKAQLKAAEERLEIKDRDYFELV---QTANTNLVEGKLE--TPLQ 1481

Query: 962  AQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQK 1021
            A  +E     ++++   EE   M ++++ + +++ Q       E+ +   NKL  L K+ 
Sbjct: 1482 ADHEE-----DSIDRRSEE---MEIKVLGEKLERNQYLLERLQEEKLELSNKLEILQKEM 1533

Query: 1022 DEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSK-QHNEE 1080
            +  ++               +  D + KL    +  EN+      + K+ +D+  +H+ +
Sbjct: 1534 ETSVL---------------LKDDLQQKLESLLS--ENI------ILKENIDTTLKHHSD 1570

Query: 1081 LQILVREQDDQIKELKETKLTFEMNIPKTEGMIISS-TIEPMSDDANNVDXXXXXXXXXX 1139
             Q  +++   +++  K   +    N P T+    S+  + P+ +                
Sbjct: 1571 TQAQLQKTQQELQLAKNLAIAASDNCPITQEKETSADCVHPLEE--------KILLLTEE 1622

Query: 1140 XXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQ----LETLNTELTGHDVVNQ-- 1193
               K  E+E+ + E++ L++   +L  E++     +I+    LE+L  E   HD   Q  
Sbjct: 1623 LHQKTNEQEKLLHEKNELEQAQVELKCEVEHLMKSMIESKSSLESLQHE--KHDTEQQLL 1680

Query: 1194 ---EQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWK-QHLAQREAD 1249
               +Q+  +  + ++L   +++L + V  L+ +I   ++ +     +  K Q L     +
Sbjct: 1681 ALKQQMQVVTQEKKELQQTHEHLTAEVDHLKENIELGLNFKNEAQQKTTKEQCLLNENKE 1740

Query: 1250 FQKTEHELRVQLSAFESKY---EQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHL 1306
             ++++H L+ ++          E  L++++ S Q+  N    ME V     +L++ +  +
Sbjct: 1741 LEQSQHRLQCEIEELMKSLKDKESALETLKESEQKVINLNQEMEMVMLEMEELKNSQRTV 1800

Query: 1307 RNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQS 1366
               +++  D + +   +  E +D+                     +    +    ++ Q 
Sbjct: 1801 IAERDQLQDDLRESVEMSIETQDDLRKAQEALQQQKDKVQELTSQISVLQEKISLLENQM 1860

Query: 1367 ILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTIT 1426
            + N+      L +               +      + E    LE  + +      + TI 
Sbjct: 1861 LYNVATVKETLSERD-DLNQSKQHLFSEIETLSLSLKEKEFALEQAEKDKADAARK-TID 1918

Query: 1427 LTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVK 1486
            +T++     N+ +QL++    +++  YE+ES L   + ++  N  H     K  ++   K
Sbjct: 1919 ITEK---ISNIEEQLLQQATNLKETLYERES-LIQCKEQLALNTEHLRETLKSKDLALGK 1974

Query: 1487 LIEELNVKITESVSLNKQVAELNKALEEEVAKTNE 1521
            + +E +    + ++L ++++ L + + E V    E
Sbjct: 1975 MEQERDEAANKVIALTEKMSSLEEQINENVTTLKE 2009



 Score =  111 bits (267), Expect = 2e-22
 Identities = 281/1464 (19%), Positives = 613/1464 (41%), Gaps = 168/1464 (11%)

Query: 217  QMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQ 276
            +  ++Q NF  ++AE    KQ L ++IE     I + +E     E  R +  L  S   Q
Sbjct: 1248 ERNELQTNFEDLKAEHDSLKQDLSENIEQS---IETQDELRAAQEELREQKQLVDSFRQQ 1304

Query: 277  ELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEI--EEKGSLEIANMTELTKKIELLEHL 334
             L+                 K S+      ++E+   E+  L+  +   L  ++ELL   
Sbjct: 1305 LLDCSVGISSPNHDAVANQEKVSLGEVNSLQSEMLRGERDELQ-TSCKALVSELELLRAH 1363

Query: 335  NCQIRQTNKELENKLATMGTESKAVSSPSKK-GSPLISRKSGRNT----ASKMKSPWSQL 389
               +   N E+  KL  +  E    S  S+   S L + K   N     A +  S  +Q 
Sbjct: 1364 VKSVEGENLEITKKLNGLEKEILGKSEESEVLKSMLENLKEDNNKLKEQAEEYSSKENQF 1423

Query: 390  SSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLI 449
            S E +   + K +++ E+ K ++       ++ D++Y     +           GK  L 
Sbjct: 1424 SLEEVFSGSQKLVDEIEVLKAQLKAAEERLEIKDRDYF----ELVQTANTNLVEGK--LE 1477

Query: 450  AQLQLEHQQ-----HMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIK--------DV 496
              LQ +H++       E   +  +G   E    + +  ++ K EL+++++         V
Sbjct: 1478 TPLQADHEEDSIDRRSEEMEIKVLGEKLERNQYLLERLQEEKLELSNKLEILQKEMETSV 1537

Query: 497  NVKD-LIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNK 555
             +KD L +KL+S   +   L + ID   K+    ++  + K +Q  +   N +  +  N 
Sbjct: 1538 LLKDDLQQKLESLLSENIILKENIDTTLKHHSDTQAQLQ-KTQQELQLAKNLAIAASDNC 1596

Query: 556  EIVRLTEE----LHHLSQKVAELEEE---KGNLQLHLVDYDSGRMIESDVYKKMIEMENL 608
             I +  E     +H L +K+  L EE   K N Q  L+ ++   + ++ V  K  E+E+L
Sbjct: 1597 PITQEKETSADCVHPLEEKILLLTEELHQKTNEQEKLL-HEKNELEQAQVELKC-EVEHL 1654

Query: 609  AETRLKAISLLES---QKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLE 665
             ++ +++ S LES   +K D  Q+L  L+Q+   V  +  ++ Q   + + +E+   HL+
Sbjct: 1655 MKSMIESKSSLESLQHEKHDTEQQLLALKQQMQVVTQEKKELQQTH-EHLTAEVD--HLK 1711

Query: 666  EQID--------ALSASKKELALVIENLKLDK---------EQLYGTIKDLENDKEDIMN 708
            E I+        A   + KE  L+ EN +L++         E+L  ++KD E+  E +  
Sbjct: 1712 ENIELGLNFKNEAQQKTTKEQCLLNENKELEQSQHRLQCEIEELMKSLKDKESALETLKE 1771

Query: 709  KLQNYIQENMDLTDKLEKMSAEKISE---------LLAKINHEEQSKIQTQFGI----DA 755
              Q  I  N ++   + +M   K S+         L   +    +  I+TQ  +    +A
Sbjct: 1772 SEQKVINLNQEMEMVMLEMEELKNSQRTVIAERDQLQDDLRESVEMSIETQDDLRKAQEA 1831

Query: 756  KIQERDLYIENIESELSKYKSRICRLE-----------ESIAVMEDRRYSLER---KADQ 801
              Q++D  ++ + S++S  + +I  LE           E+++  +D   S +    + + 
Sbjct: 1832 LQQQKDK-VQELTSQISVLQEKISLLENQMLYNVATVKETLSERDDLNQSKQHLFSEIET 1890

Query: 802  LGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEE 861
            L   L+EK+ A  +    + +   +   + +    +E+QLL+     KE   + + L++ 
Sbjct: 1891 LSLSLKEKEFALEQAEKDKADAARKTIDITEKISNIEEQLLQQATNLKETLYERESLIQC 1950

Query: 862  NQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQK 921
             + L ++   +++   +      + +    E+      L +  S+L+   +E+ T + + 
Sbjct: 1951 KEQLALNTEHLRETLKSKDLALGKMEQERDEAANKVIALTEKMSSLEEQINENVTTLKEG 2010

Query: 922  KKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEEL 981
            + E E   ++  ++ +S+ + +++      K+++ + + E ++ E  N I+NL   +  L
Sbjct: 2011 EGEKETFYLQRPSKQQSSSQMEELRESLKTKDLQ-LEEAEKEISEATNEIKNLTAKISSL 2069

Query: 982  NK---MNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVS 1038
             +    N  ++++ V +++       +Q ++E+ +L+  LK +D       ++ + A   
Sbjct: 2070 EEEILQNASILNEAVSERENLRHS-KQQLVSELEQLSLTLKSRDHAFAQSKREKDEAVNK 2128

Query: 1039 YMSMVSDYE---SKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKEL 1095
              S+  + +    ++ +F    E+++E+   +S++L   K    ELQ+L ++++D   +L
Sbjct: 2129 IASLAEEIKILTKEMDEFRDSKESLQEQSSHLSEELCTYKT---ELQMLKQQKEDINNKL 2185

Query: 1096 KE-TKLTFEM--NIPKTEGMIISSTIEPMSDDANNVDX--XXXXXXXXXXXLKVQEEEEF 1150
             E  K   E+  ++   +  +    +E  ++   N +              L++ + E  
Sbjct: 2186 AEKVKEVDELLQHLSSLKEQLDQIQMELRNEKLRNYELCEKMDIMEKEISVLRLMQNEPQ 2245

Query: 1151 IQERSVLQEQSA--KLNTELQECYTKIIQ--------LETLNTELTGHDVVNQEQINQLK 1200
             +E  V +        N E+QE   KI          L +L++EL      ++  +  +K
Sbjct: 2246 QEEDDVAERMDILESRNQEIQELMEKISAVYSEQHTLLSSLSSELQKETEAHKHCMLNIK 2305

Query: 1201 SKLEQLNTENDNLLSTV-AELRSSISSAVDQRG--FEIAELWKQH--LAQREADF---QK 1252
              L    + +   L T   +L + + + +++    +  A + + H  +   E D    QK
Sbjct: 2306 ESLSSTLSRSFGSLQTEHVKLNTQLQTLLNKFKVVYRTAAVKEDHSLIKDYEKDLAAEQK 2365

Query: 1253 TEHELRVQLSAFESKYEQLLDSVQS----------------------STQEETNKI-VTM 1289
               ELR+QL   E    +  DS                         S Q++ +++ V +
Sbjct: 2366 RHDELRLQLQCLEQHGRKWSDSASEELKFCEIEFLNELLFKKANIIQSVQDDFSEVQVFL 2425

Query: 1290 EQVTS-LQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXX 1348
             QV S LQ +L+ K+  ++ L+E + D+    + L   ++ E                  
Sbjct: 2426 NQVGSTLQEELEHKKGFMQWLEE-FGDLHVDAKKLSEGMQQENRRIASTIQLLTKRLKAV 2484

Query: 1349 XXD-LRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTH 1407
                ++ E   Y    E  +    E+N +L +               + +  A++L +  
Sbjct: 2485 VQSKIQREITVYLNQFEAKLQEKKEQNKELMRRMEHHGPSASV----MEEENARLLGILK 2540

Query: 1408 QLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMH 1467
             ++ +  ++  +       L    D+  +  +++   + ++  L+   E+EL  +++K+ 
Sbjct: 2541 TVQDESKKLQSRIKMLENELNLVKDDAMHKGEKVAILQDKL--LSRNAEAELNAMQVKLT 2598

Query: 1468 ENANHYETMQKESE-IER------VKLIEELNVKITESVSLNKQVAELNKALEEEVAKTN 1520
            +  ++ +   KE E +++      V   EE++   T+ V +  +  + +KA ++E+A   
Sbjct: 2599 KKQDNLQAAMKEIENLQKMVAKGAVPYKEEIDNLKTKVVKIEMEKIKYSKATDQEIA--- 2655

Query: 1521 EMQTALENQEIEIVTLNDEITNLQ 1544
             +++ LE++E  +  L +E+   Q
Sbjct: 2656 YLKSCLEDKEEGLRRLKEELRRAQ 2679



 Score =  109 bits (263), Expect = 5e-22
 Identities = 275/1375 (20%), Positives = 579/1375 (42%), Gaps = 118/1375 (8%)

Query: 297  KQSIEPSCEEKTEIEEKGSLEIANMTE-LTKKIELLEHL-NCQIRQTNKELENKLATMGT 354
            +Q ++   EEK E+ +   L+IA + E L+ K + LE + N +    N E++  +     
Sbjct: 559  QQQLQSKEEEKKELVQSFELKIAELEEQLSVKAKNLEMVTNSREHSINAEVQTDV----- 613

Query: 355  ESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTD-----KKINKNEIAK 409
            E + V    K+ S L    SG N AS      S +  + L+   D     +K+ + +I  
Sbjct: 614  EKEVVR---KEMSVL--GDSGYN-ASNSDLQDSSVDGKRLSSSHDECIEHRKMLEQKIVD 667

Query: 410  LEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVG 469
            LE  I++LNK   + +   SE+D             +   A   LE    M       + 
Sbjct: 668  LEEFIENLNKKSENDKQKSSEQDFMESIQLCEAIMAEKANA---LEELALMRDNFDNIIL 724

Query: 470  TNTEDVNEIAKVQEQLK--QELND------EIKDVNVKDLIEK---LKSAEEQITQLNDE 518
             N     EIA ++  LK  QE N+      E +  +   LI +   LK   E     N  
Sbjct: 725  ENETLKREIADLERSLKENQETNEFEILEKETQKEHEAQLIHEIGSLKKLVENAEMYNQN 784

Query: 519  IDAANKNMIKVKSNHKLKLKQMQKTIDNFSK------VSDSNKEIVRLTEELHHLSQKVA 572
            ++   +   K+    +++L +++K  DN  K      +S S  +  +L EE+  L Q ++
Sbjct: 785  LEEDLETKTKLLKEQEIQLAELRKRADNLQKKVRNFDLSVSMGDSEKLCEEIFQLKQSLS 844

Query: 573  ELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISL----LESQKFDLVQ 628
            + E    + Q       S  +   ++ +KM +  N    + KA SL    LE++K +  +
Sbjct: 845  DAEAVTRDAQKECSFLRSENL---ELKEKMEDTSNWYNQKEKAASLFEKQLETEKSNYKK 901

Query: 629  ELHILQQKYDEVEDKLADISQLQSDQVCSEIKS-VHLEEQIDALSASKKELALVIENLKL 687
                LQ++     +++  ++ L + +V  ++ S V LE+++   S  + E AL  +N   
Sbjct: 902  MEADLQKELQSAFNEINYLNGLLAGKVPRDLLSRVELEKKVSEFS-KQLEKALEEKNALE 960

Query: 688  DKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKI 747
            ++       K L N+ E + N++    +E M L  + E  SA  IS+   +I  +EQS+ 
Sbjct: 961  NEVTCLSEYKFLPNEVECLKNQISKASEEIMLLKQEGEH-SASIISK--QEIIMQEQSEQ 1017

Query: 748  QTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQ 807
              Q  +  ++      ++  E +  + K     L E     +     L R+ + L   ++
Sbjct: 1018 ILQ--LTDEVTHTQSKVQQTEEQYLEMKKMHDDLFEKYIRNKSEAEDLLREMENLKGTME 1075

Query: 808  EKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKK--NQILLEENQNL 865
              +   ++   + +E +     L+ H++    Q ++       L        L+E N   
Sbjct: 1076 SVEVKIADTKHELEETIRDKEQLL-HEKKYFFQAMQTIFPITPLSDSLPPSKLVEGNSQD 1134

Query: 866  QISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHE--HQTLIVQKKK 923
             I ++D         E+ N     E+E    + Q+ DL + L+ +  +   ++ + + K+
Sbjct: 1135 PIEINDYHNLIALATERNNIMVCLETERNSLKEQVIDLNTQLQSLQAQSIEKSDLQKPKQ 1194

Query: 924  EIEDLEIEFNTQIE---SAIRDKKVLNEKYE-KNIEYVTQLEAQLQEYKNNIENLNMNVE 979
            ++E+ E++   ++E     + D ++  EK + +N+E   +L+  LQE   NI  +  N  
Sbjct: 1195 DLEEGEVKLLLEMELLKGHLTDSQLSIEKLQLENLEVTEKLQT-LQEEMKNI-TIERNEL 1252

Query: 980  ELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSY 1039
            + N  +L+     +++  +++ + + +  +E+      L+++ + + +  Q++ +  V  
Sbjct: 1253 QTNFEDLKAEHDSLKQDLSENIEQSIETQDELRAAQEELREQKQLVDSFRQQLLDCSVGI 1312

Query: 1040 MSMVSDYESKLAQFTT-KLENMEEEMQRVSKQLLDS--KQHNEELQIL---VREQDDQIK 1093
             S   D  +   + +  ++ +++ EM R  +  L +  K    EL++L   V+  + +  
Sbjct: 1313 SSPNHDAVANQEKVSLGEVNSLQSEMLRGERDELQTSCKALVSELELLRAHVKSVEGENL 1372

Query: 1094 ELKETKLTFEMNI--PKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQE----E 1147
            E+ +     E  I     E  ++ S +E + +D N +               ++E     
Sbjct: 1373 EITKKLNGLEKEILGKSEESEVLKSMLENLKEDNNKLKEQAEEYSSKENQFSLEEVFSGS 1432

Query: 1148 EEFIQERSVLQEQ--SAKLNTELQE-CYTKIIQLETLNTELTGHDVVNQEQINQLKSKLE 1204
            ++ + E  VL+ Q  +A+   E+++  Y +++Q  T NT L    +    Q +  +  ++
Sbjct: 1433 QKLVDEIEVLKAQLKAAEERLEIKDRDYFELVQ--TANTNLVEGKLETPLQADHEEDSID 1490

Query: 1205 QLNTEND-NLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQ-KTEHELRVQLS 1262
            + + E +  +L    E    +   + +   E++   K  + Q+E +     + +L+ +L 
Sbjct: 1491 RRSEEMEIKVLGEKLERNQYLLERLQEEKLELSN--KLEILQKEMETSVLLKDDLQQKLE 1548

Query: 1263 AFESKYEQLLDSV------QSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEK--YA 1314
            +  S+   L +++       S TQ +  K  T +++   +N      ++    QEK   A
Sbjct: 1549 SLLSENIILKENIDTTLKHHSDTQAQLQK--TQQELQLAKNLAIAASDNCPITQEKETSA 1606

Query: 1315 DVINQIE---ILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNIN 1371
            D ++ +E   +L +E   +K                   +L+ E +   +   +S  ++ 
Sbjct: 1607 DCVHPLEEKILLLTEELHQKTNEQEKLLHEKNELEQAQVELKCEVEHLMKSMIESKSSL- 1665

Query: 1372 EENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRN 1431
             E+ Q +K              +V   E K L+ TH+    + +  ++  E  +      
Sbjct: 1666 -ESLQHEKHDTEQQLLALKQQMQVVTQEKKELQQTHEHLTAEVDHLKENIELGLNFKNEA 1724

Query: 1432 DEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEEL 1491
             +     Q L+   K +E   +  + E+  L   + +  +  ET+ KESE + + L +E+
Sbjct: 1725 QQKTTKEQCLLNENKELEQSQHRLQCEIEELMKSLKDKESALETL-KESEQKVINLNQEM 1783

Query: 1492 NVKITESVSL-NKQ---VAELNKALEEEVAKTNEM-----------QTALENQEIEIVTL 1536
             + + E   L N Q   +AE ++ L++++ ++ EM           Q AL+ Q+ ++  L
Sbjct: 1784 EMVMLEMEELKNSQRTVIAERDQ-LQDDLRESVEMSIETQDDLRKAQEALQQQKDKVQEL 1842

Query: 1537 NDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDL 1591
              +I+ LQ  +    +++  +V+   +T   RD+   N   + L   +    L L
Sbjct: 1843 TSQISVLQEKISLLENQMLYNVATVKETLSERDDL--NQSKQHLFSEIETLSLSL 1895



 Score = 66.9 bits (156), Expect = 4e-09
 Identities = 177/862 (20%), Positives = 366/862 (42%), Gaps = 102/862 (11%)

Query: 141  LGDVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXX 200
            L +V  +  T+ E+D+     Q     +ET  L L+    EK+  +E   K         
Sbjct: 1861 LYNVATVKETLSERDDLNQSKQHLFSEIETLSLSLK----EKEFALEQAEKDKADAARKT 1916

Query: 201  XXXXXXXXXXXEDTKQQMTKMQENFIAMEA--EWKDE----KQRLLKDIESKDVRISSLE 254
                       E   QQ T ++E     E+  + K++     + L + ++SKD+ +  +E
Sbjct: 1917 IDITEKISNIEEQLLQQATNLKETLYERESLIQCKEQLALNTEHLRETLKSKDLALGKME 1976

Query: 255  EANKLLEAARFEISL--EHSKLAQELEQ--XXXXXXXXXXXXXXLAKQSIEPSCEEKTEI 310
            +     EAA   I+L  + S L +++ +                L + S + S  +  E+
Sbjct: 1977 QERD--EAANKVIALTEKMSSLEEQINENVTTLKEGEGEKETFYLQRPSKQQSSSQMEEL 2034

Query: 311  EEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGT-ESKAVSSPSKKGSPL 369
             E  SL+       TK ++ LE    +I +   E++N  A + + E + + + S     +
Sbjct: 2035 RE--SLK-------TKDLQ-LEEAEKEISEATNEIKNLTAKISSLEEEILQNASILNEAV 2084

Query: 370  ISRKSGRNTASKMKSPWSQLSSETLNQD-------TDKKINKNEIAKLEMVIQSLNKDLV 422
              R++ R++  ++ S   QLS    ++D        +K    N+IA L   I+ L K++ 
Sbjct: 2085 SERENLRHSKQQLVSELEQLSLTLKSRDHAFAQSKREKDEAVNKIASLAEEIKILTKEM- 2143

Query: 423  DKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQ 482
              +     K++             T   +LQ+  QQ  +  +   +    ++V+E+ +  
Sbjct: 2144 --DEFRDSKESLQEQSSHLSEELCTYKTELQMLKQQKEDINN--KLAEKVKEVDELLQHL 2199

Query: 483  EQLKQELND---EIKDVNVK--DLIEKLKSAEEQITQL--------NDEIDAANKNMIKV 529
              LK++L+    E+++  ++  +L EK+   E++I+ L         +E D A +  I  
Sbjct: 2200 SSLKEQLDQIQMELRNEKLRNYELCEKMDIMEKEISVLRLMQNEPQQEEDDVAERMDILE 2259

Query: 530  KSNHKLKLKQMQKTIDNFSK----VSDSNKEIVRLTEELHHLSQKVAE-----LEEEKGN 580
              N +++ + M+K    +S+    +S  + E+ + TE   H    + E     L    G+
Sbjct: 2260 SRNQEIQ-ELMEKISAVYSEQHTLLSSLSSELQKETEAHKHCMLNIKESLSSTLSRSFGS 2318

Query: 581  LQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEV 640
            LQ   V  ++      + +K +     + E      SL++  + DL  E    Q+++DE+
Sbjct: 2319 LQTEHVKLNTQLQTLLNKFKVVYRTAAVKEDH----SLIKDYEKDLAAE----QKRHDEL 2370

Query: 641  EDKLADISQ---LQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIK 697
              +L  + Q     SD    E+K   +E   + L   KK  A +I++++ D  ++   + 
Sbjct: 2371 RLQLQCLEQHGRKWSDSASEELKFCEIEFLNELL--FKK--ANIIQSVQDDFSEVQVFLN 2426

Query: 698  DLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQ-----TQFG 752
             + +  ++ +   + ++Q   +  D    + A+K+SE + + N    S IQ      +  
Sbjct: 2427 QVGSTLQEELEHKKGFMQWLEEFGDL--HVDAKKLSEGMQQENRRIASTIQLLTKRLKAV 2484

Query: 753  IDAKIQ-ERDLYIENIESELSKYKSR----ICRLEE---SIAVMED---RRYSLERKADQ 801
            + +KIQ E  +Y+   E++L + K +    + R+E    S +VME+   R   + +    
Sbjct: 2485 VQSKIQREITVYLNQFEAKLQEKKEQNKELMRRMEHHGPSASVMEEENARLLGILKTVQD 2544

Query: 802  LGSYLQEKQKAY-SEYTIQEDELVN---RLAVLMDH--DRVVEKQLLEIEHENKELQKKN 855
                LQ + K   +E  + +D+ ++   ++A+L D    R  E +L  ++ +  + Q   
Sbjct: 2545 ESKKLQSRIKMLENELNLVKDDAMHKGEKVAILQDKLLSRNAEAELNAMQVKLTKKQDNL 2604

Query: 856  QILLEENQNLQISLSDMQQHYNALVEK-ANRTDLAESESTKYQTQLRDLESNLKRITHEH 914
            Q  ++E +NLQ  ++     Y   ++    +    E E  KY        + LK    + 
Sbjct: 2605 QAAMKEIENLQKMVAKGAVPYKEEIDNLKTKVVKIEMEKIKYSKATDQEIAYLKSCLEDK 2664

Query: 915  QTLIVQKKKEIEDLEIEFNTQI 936
            +  + + K+E+   + + +T +
Sbjct: 2665 EEGLRRLKEELRRAQADNDTTV 2686



 Score = 58.4 bits (135), Expect = 2e-06
 Identities = 178/931 (19%), Positives = 359/931 (38%), Gaps = 89/931 (9%)

Query: 664  LEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDK 723
            L++Q++ L +S +  A  +   K +  QL   IK L  ++ED +  L N +  +   + +
Sbjct: 356  LKKQLENLESSSETKAQAMA--KEEHTQLLAEIKQLHKEREDRIWHLTNIVVASSQESQQ 413

Query: 724  LEKMSAEK-ISELLAKINH----------EEQSKIQTQFGIDAKIQERDLYIENIESELS 772
             +++  ++ ++    KI +          +  S++   F   AK  +   + E  +S  +
Sbjct: 414  DQRVKRKRRVTWAPGKIQNSLHASGVSDFDMLSRLPGNFSKKAKFSDMPSFPEIDDSVCT 473

Query: 773  KYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMD 832
            ++       ++++++M+      E     L S +  ++K     ++ +   ++       
Sbjct: 474  EFSD----FDDALSMMDSNGIDAEWN---LASKVTHREKTSLHQSMIDFGQISDSVQF-- 524

Query: 833  HDRVVEKQLLEIEHENKELQKKNQILLE-ENQNLQISLSDMQQHYNALVE--KANRTDLA 889
            HD   E QL  +  ++ ++ +  +   E E  +LQ  L   ++    LV+  +    +L 
Sbjct: 525  HDSSKENQLQYLPKDSGDMAECRKASFEKEITSLQQQLQSKEEEKKELVQSFELKIAELE 584

Query: 890  ESESTKYQTQLRDLESNLKRITHEHQTLIVQK--KKEIEDLEIE----FNTQIESAIRDK 943
            E  S K +       S    I  E QT + ++  +KE+  L        N+ ++ +  D 
Sbjct: 585  EQLSVKAKNLEMVTNSREHSINAEVQTDVEKEVVRKEMSVLGDSGYNASNSDLQDSSVDG 644

Query: 944  KVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDY 1003
            K L+  +++ IE+   LE ++ + +  IENLN   E   + + E     ++  Q      
Sbjct: 645  KRLSSSHDECIEHRKMLEQKIVDLEEFIENLNKKSENDKQKSSE--QDFMESIQLCEAIM 702

Query: 1004 TEQYINEINKLNALLKQKDEEIIALNQKINNAQVSY-MSMVSDYESKLAQFTTKLENMEE 1062
             E+  N + +L AL++   + II  N+ +         S+  + E+   +   K    E 
Sbjct: 703  AEK-ANALEEL-ALMRDNFDNIILENETLKREIADLERSLKENQETNEFEILEKETQKEH 760

Query: 1063 EMQRVSK-QLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPM 1121
            E Q + +   L     N E+     E+D + K    TKL  E  I   E   +    + +
Sbjct: 761  EAQLIHEIGSLKKLVENAEMYNQNLEEDLETK----TKLLKEQEIQLAE---LRKRADNL 813

Query: 1122 SDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETL 1181
                 N D                  EE  Q +  L +  A      +EC    ++ E L
Sbjct: 814  QKKVRNFDLSVSMGDSEKLC------EEIFQLKQSLSDAEAVTRDAQKEC--SFLRSENL 865

Query: 1182 NTELTGHDVVNQEQINQLKSKL--EQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELW 1239
              +    D  N     +  + L  +QL TE  N     A+L+  + SA ++  +      
Sbjct: 866  ELKEKMEDTSNWYNQKEKAASLFEKQLETEKSNYKKMEADLQKELQSAFNEINY-----L 920

Query: 1240 KQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEET---NKIVTMEQVTSLQ 1296
               LA +      +  EL  ++S F  + E+ L+   +   E T          +V  L+
Sbjct: 921  NGLLAGKVPRDLLSRVELEKKVSEFSKQLEKALEEKNALENEVTCLSEYKFLPNEVECLK 980

Query: 1297 NKLQDKEEHLRNLQ---EKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLR 1353
            N++    E +  L+   E  A +I++ EI+  E  ++ +                     
Sbjct: 981  NQISKASEEIMLLKQEGEHSASIISKQEIIMQEQSEQILQLTDEVTHTQSKVQQTEEQYL 1040

Query: 1354 TENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLE--L 1411
               + +  + E+ I N +E    L++               +   E K+ +  H+LE  +
Sbjct: 1041 EMKKMHDDLFEKYIRNKSEAEDLLREMENLKGT--------MESVEVKIADTKHELEETI 1092

Query: 1412 KDSE--IYQKTHEY----TI-TLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRL 1464
            +D E  +++K + +    TI  +T  +D     +      +  IE   Y     LA  R 
Sbjct: 1093 RDKEQLLHEKKYFFQAMQTIFPITPLSDSLPPSKLVEGNSQDPIEINDYHNLIALATERN 1152

Query: 1465 KMHENANHYETMQKESEIERVKLIEELNVKITESVSLNK-----QVAELNKALEEEVAK- 1518
             +           KE  I+    ++ L  +  E   L K     +  E+   LE E+ K 
Sbjct: 1153 NIMVCLETERNSLKEQVIDLNTQLQSLQAQSIEKSDLQKPKQDLEEGEVKLLLEMELLKG 1212

Query: 1519 -TNEMQTALENQEIEIVTLNDEITNLQNMVR 1548
               + Q ++E  ++E + + +++  LQ  ++
Sbjct: 1213 HLTDSQLSIEKLQLENLEVTEKLQTLQEEMK 1243



 Score = 45.2 bits (102), Expect = 0.015
 Identities = 78/357 (21%), Positives = 160/357 (44%), Gaps = 36/357 (10%)

Query: 465  LIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANK 524
            L  VG+  ++  E  K   Q  +E  D    V+ K L E ++    +I      +    K
Sbjct: 2425 LNQVGSTLQEELEHKKGFMQWLEEFGD--LHVDAKKLSEGMQQENRRIASTIQLLTKRLK 2482

Query: 525  NMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLH 584
             +++ K   ++ +  + +      +  + NKE++R  E  H  S  V E EE    L + 
Sbjct: 2483 AVVQSKIQREITV-YLNQFEAKLQEKKEQNKELMRRMEH-HGPSASVME-EENARLLGIL 2539

Query: 585  LVDYDSGRMIESDVYKKMIEME-NLAET----RLKAISLLESQKF--DLVQELHILQQKY 637
                D  + ++S +  KM+E E NL +     + + +++L+ +    +   EL+ +Q K 
Sbjct: 2540 KTVQDESKKLQSRI--KMLENELNLVKDDAMHKGEKVAILQDKLLSRNAEAELNAMQVKL 2597

Query: 638  DEVEDKL-ADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDK--EQLYG 694
             + +D L A + ++++ Q      +V  +E+ID L    K + + +E +K  K  +Q   
Sbjct: 2598 TKKQDNLQAAMKEIENLQKMVAKGAVPYKEEIDNLKT--KVVKIEMEKIKYSKATDQEIA 2655

Query: 695  TIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGID 754
             +K    DKE+ + +L+          ++L +  A+  + +    ++++ S      G  
Sbjct: 2656 YLKSCLEDKEEGLRRLK----------EELRRAQADNDTTVCVPKDYQKASTFPVTCGGG 2705

Query: 755  AKIQERD--LYIEN----IESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSY 805
            + I +    L +++    +E ELS YK +   L  +++  EDR+   + K+D   S+
Sbjct: 2706 SGIVQSTAMLVLQSEKAALERELSHYKKKYHHLSRTMSSSEDRK-KTKAKSDAHSSH 2761


>UniRef50_A2D7K4 Cluster: Putative uncharacterized protein; n=1;
            Trichomonas vaginalis G3|Rep: Putative uncharacterized
            protein - Trichomonas vaginalis G3
          Length = 994

 Score =  125 bits (302), Expect = 9e-27
 Identities = 192/1000 (19%), Positives = 424/1000 (42%), Gaps = 58/1000 (5%)

Query: 596  SDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQV 655
            +D  K + E+        K +  L ++  D   E+  ++ +Y+E  D+    SQ + +Q 
Sbjct: 2    NDNEKWLYEINKKIAALTKIVFQLHTEATDRKDEVARMKVRYEEELDQAFKASQDRIEQA 61

Query: 656  CSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQ 715
              E+++     +     A + E   + +      +QL    K + ++    +N+L+  ++
Sbjct: 62   QKEVQNYKQSIEKTVRQAYESEFNKIKKLYDQANDQLNSKSKSIIDNSNKRLNQLKKEVE 121

Query: 716  ENMDLTDKLEKMSA--EKISELLAKINHEEQSKIQTQFGID--AKIQERDLYIENIESEL 771
               DL  K +  SA  +  S+ L KI  +  +KI+ +   D   ++ E +     +    
Sbjct: 122  ---DLKKKADSQSALFDNASKELEKIAADTVAKIEDKHKKDLAKRVTEANKKYNQLVVAT 178

Query: 772  SKYKSRI-CRLEESIAVMEDRRYSLER-KADQLGSYLQEKQKAYSEYTIQEDEL---VNR 826
            SK +  +  R E+ +  ++++  + ++ +++ L S  ++         I  D +   V+ 
Sbjct: 179  SKKEEELKARFEKELQDLKNQLAAGQKNQSEMLSSKQKDIDSKIKRLEITRDLVQRGVDE 238

Query: 827  LAVLMD-HDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANR 885
            L  L++   + VE +L +I+ + + L  +++I L E   L+  + + Q +++   E A  
Sbjct: 239  LKQLLETQKKQVEDKLKQIQEQRQRLANQSEIELHE---LKHKMKESQNNHDQ--EMAKI 293

Query: 886  TDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRD-KK 944
              + +     ++  + DL+S +++   EH+  + + +K+ ++   +   + +  ++  K+
Sbjct: 294  QSMIDQAQADHEKAVNDLKSQVEKAKLEHEQKLQELQKQSKNSAEDGEQKKKKLLQQHKQ 353

Query: 945  VLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYT 1004
             +++   K+ ++V++ E + QE +  +E+L    E   K     I+K  +          
Sbjct: 354  AMDDLKAKHAQFVSESEKREQELQKQLEDLQRKHESSMKKIRGDIEKEKKSHADNMAMLD 413

Query: 1005 EQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEM 1064
             Q+  E+ +   L ++ ++E++ L ++  NA        ++  S L     ++E + EE+
Sbjct: 414  TQHQQELQR---LAEEHEKEMMKLKKEYENAS-------NNSNSSLKDILDEIERVREEI 463

Query: 1065 QRVSKQLLDS--KQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMS 1122
            ++  K+  D   ++  E  ++  + + D  K + E K   E  + K +    +   E   
Sbjct: 464  KKKIKEGEDEIIRKQKERQEMEEKLKSDHEKRMSEIKQNHEERMKKLDEETQAKIDEMNR 523

Query: 1123 DDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSV-LQEQSAKLNTELQECYTKIIQLETL 1181
                N+                  + E   +R + L E  A    ++ E   KI   E+ 
Sbjct: 524  KHQENMKRIETEAQEKLSRDSAALKNELESQRQIQLSELKATWKKKINEIKQKI---ESR 580

Query: 1182 NTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQ 1241
                   +   QE+  + ++K+EQL  E + L    AE +  I+    ++   + +L K+
Sbjct: 581  QKAKADAEHFLQEETAKRQAKIEQLRQELETLKKNWAEEKEKINKEYSEK---LEKLKKE 637

Query: 1242 HLAQREADFQKTEHELRVQLSAFESKYEQLLDSV--QSSTQEETNKIVTMEQVTSLQNKL 1299
            +    EA+ +K E + R++    +++Y++ +D +  Q + +EE  K +  +    +Q K 
Sbjct: 638  N---EEAE-RKAEEQRRLK----DAEYQKAIDDLKKQLNDEEEKKKKIISDLEQKIQQKE 689

Query: 1300 QDKEEHLRNLQEKYADVI--NQIEI--LRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTE 1355
            ++ EE L+   E+   +    Q EI  L  +I D K                    L+ E
Sbjct: 690  KENEEELKRQNEEIEKLTQKRQTEIHELELKINDLKAETNKKVQEIDEEKKKELSKLQQE 749

Query: 1356 NQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXR-VNDAEAKVLELTHQLELKDS 1414
                K+  EQ I  + ++  Q+KK              +   DA  ++  +  + E   S
Sbjct: 750  YDEIKKKGEQEIERLQKQLDQIKKEHEQQLNEIKAKIAKEEEDARQRLDAMKQENERILS 809

Query: 1415 EIYQKTHEYTITLTQRNDEFENVRQQLV-EYEKRIEDLTYEKESELAILRLKMHENANHY 1473
            EI QK  +    L +   + ++   +L  ++ +R+     + E++L IL+ K        
Sbjct: 810  EIKQKHKKEMDVLNEELRKLQDEECELERKHNERLAQQQRDYENKLDILKKKYDAEKEKI 869

Query: 1474 ETMQKESEIERVKLIEEL--NVKITESVSLNKQV-AELNKALEEEVAKTNEMQTALENQE 1530
             T   + E E+ + I EL    +  E    N++   E  + +++  A   E   A+E  +
Sbjct: 870  TTEIAKIEQEKKQRIAELEEETRTWEDRYNNREARPEDLEKIQKLEALIAERSAAIEKVQ 929

Query: 1531 IEIVTLNDEITNLQNMV-RASSSKIQKHVSFASDTKQGRD 1569
             E+     E+ N +    +  ++K Q +V  A + K  RD
Sbjct: 930  SELKRYQAELLNRETTYNKVFNNKPQVNVLSALERKARRD 969



 Score =  121 bits (291), Expect = 2e-25
 Identities = 202/952 (21%), Positives = 438/952 (46%), Gaps = 111/952 (11%)

Query: 401  KINKNEIAKLEMVIQSLNKDLVD-KEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQH 459
            +INK +IA L  ++  L+ +  D K+ V   K                 I Q Q E Q +
Sbjct: 10   EINK-KIAALTKIVFQLHTEATDRKDEVARMKVRYEEELDQAFKASQDRIEQAQKEVQNY 68

Query: 460  MEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDV--NVKDLIEKLKSAEEQITQLND 517
             +            + N+I K+ +Q   +LN + K +  N    + +LK   E + +  D
Sbjct: 69   KQSIEKTVRQAYESEFNKIKKLYDQANDQLNSKSKSIIDNSNKRLNQLKKEVEDLKKKAD 128

Query: 518  E----IDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKV-A 572
                  D A+K + K+ ++   K++   K  D   +V+++NK+  +L        +++ A
Sbjct: 129  SQSALFDNASKELEKIAADTVAKIEDKHKK-DLAKRVTEANKKYNQLVVATSKKEEELKA 187

Query: 573  ELEEEKGNL--QLHLVDYDSGRMIES---DVYKKMIEMENLAETRLKAIS----LLESQK 623
              E+E  +L  QL     +   M+ S   D+  K+  +E   +   + +     LLE+QK
Sbjct: 188  RFEKELQDLKNQLAAGQKNQSEMLSSKQKDIDSKIKRLEITRDLVQRGVDELKQLLETQK 247

Query: 624  FDLVQELHILQQKYDEV----EDKLADI------SQLQSDQVCSEIKSVHLEEQIDALSA 673
              +  +L  +Q++   +    E +L ++      SQ   DQ  ++I+S+  + Q D   A
Sbjct: 248  KQVEDKLKQIQEQRQRLANQSEIELHELKHKMKESQNNHDQEMAKIQSMIDQAQADHEKA 307

Query: 674  SKKELALVIENLKLDKEQ-LYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKI 732
               +L   +E  KL+ EQ L    K  +N  ED   K +  +Q++    D L+   A+ +
Sbjct: 308  VN-DLKSQVEKAKLEHEQKLQELQKQSKNSAEDGEQKKKKLLQQHKQAMDDLKAKHAQFV 366

Query: 733  SELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDR- 791
            SE     + + + ++Q Q  ++   ++ +  ++ I  ++ K K       +++A+++ + 
Sbjct: 367  SE-----SEKREQELQKQ--LEDLQRKHESSMKKIRGDIEKEKKSHA---DNMAMLDTQH 416

Query: 792  RYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDH-DRV---VEKQLLEIEHE 847
            +  L+R A++   + +E  K   EY    +   + L  ++D  +RV   ++K++ E E E
Sbjct: 417  QQELQRLAEE---HEKEMMKLKKEYENASNNSNSSLKDILDEIERVREEIKKKIKEGEDE 473

Query: 848  NKELQKKNQILLEE-NQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESN 906
                QK+ Q + E+   + +  +S+++Q++   ++K     L E    K     R  + N
Sbjct: 474  IIRKQKERQEMEEKLKSDHEKRMSEIKQNHEERMKK-----LDEETQAKIDEMNRKHQEN 528

Query: 907  LKRITHEHQTLIVQKKKEIEDLEIEFNTQIE-SAIRD--KKVLNEKYEKNIEYVTQLEAQ 963
            +KRI  E Q  + +    +++ E+E   QI+ S ++   KK +NE  +K IE   + +A 
Sbjct: 529  MKRIETEAQEKLSRDSAALKN-ELESQRQIQLSELKATWKKKINEIKQK-IESRQKAKAD 586

Query: 964  LQEY-KNNIENLNMNVEELNKMNLELIDKH-VQKQQTQSPDYTEQYINEINKLNALLKQK 1021
             + + +         +E+L +  LE + K+  ++++  + +Y+E+ + ++ K N   ++K
Sbjct: 587  AEHFLQEETAKRQAKIEQL-RQELETLKKNWAEEKEKINKEYSEK-LEKLKKENEEAERK 644

Query: 1022 DEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEEL 1081
             EE     +++ +A+  Y   + D + +L     K + +  ++++  +Q    K++ EEL
Sbjct: 645  AEE----QRRLKDAE--YQKAIDDLKKQLNDEEEKKKKIISDLEQKIQQ--KEKENEEEL 696

Query: 1082 QILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXX 1141
                + Q+++I++L + +        +TE   +   I  +  + N               
Sbjct: 697  ----KRQNEEIEKLTQKR--------QTEIHELELKINDLKAETNK-------------- 730

Query: 1142 LKVQE-EEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLK 1200
             KVQE +EE  +E S LQ++  ++  + ++      ++E L  +L      +++Q+N++K
Sbjct: 731  -KVQEIDEEKKKELSKLQQEYDEIKKKGEQ------EIERLQKQLDQIKKEHEQQLNEIK 783

Query: 1201 SKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQ 1260
            +K+ +   +    L  + +    I S + Q+  +  ++  + L + + +  + E +   +
Sbjct: 784  AKIAKEEEDARQRLDAMKQENERILSEIKQKHKKEMDVLNEELRKLQDEECELERKHNER 843

Query: 1261 LSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEK 1312
            L+  +  YE  LD ++     E  KI T  ++  ++   Q+K++ +  L+E+
Sbjct: 844  LAQQQRDYENKLDILKKKYDAEKEKITT--EIAKIE---QEKKQRIAELEEE 890



 Score = 50.0 bits (114), Expect = 5e-04
 Identities = 90/459 (19%), Positives = 185/459 (40%), Gaps = 34/459 (7%)

Query: 154 KDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXED 213
           K+   S  Q+++  ++ T    ++KINE  Q IE++ KA                   E 
Sbjct: 548 KNELESQRQIQLSELKAT---WKKKINEIKQKIESRQKAKADAEHFLQEETAKRQAKIEQ 604

Query: 214 TKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRI-SSLEEANKLLEAARFEISLEHS 272
            +Q++  +++N       W +EK+++ K+   K  ++    EEA +  E  R     E+ 
Sbjct: 605 LRQELETLKKN-------WAEEKEKINKEYSEKLEKLKKENEEAERKAEEQRRLKDAEYQ 657

Query: 273 KLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLE 332
           K   +L++                +Q I+   +E  E  ++ + EI  +T+  K+   + 
Sbjct: 658 KAIDDLKKQLNDEEEKKKKIISDLEQKIQQKEKENEEELKRQNEEIEKLTQ--KRQTEIH 715

Query: 333 HLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSE 392
            L  +I     E   K+  +  E K   S  ++    I +K G     +++    Q+  E
Sbjct: 716 ELELKINDLKAETNKKVQEIDEEKKKELSKLQQEYDEI-KKKGEQEIERLQKQLDQIKKE 774

Query: 393 ---TLNQDTDKKINKNEIAKL---------EMVIQSLNKDLVDKEYVISEKDTXXXXXXX 440
               LN+   K   + E A+          E ++  + +    +  V++E+         
Sbjct: 775 HEQQLNEIKAKIAKEEEDARQRLDAMKQENERILSEIKQKHKKEMDVLNEELRKLQDEEC 834

Query: 441 XXXGK-DTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQ---ELNDEIKDV 496
               K +  +AQ Q +++  ++     +     +   EIAK++++ KQ   EL +E +  
Sbjct: 835 ELERKHNERLAQQQRDYENKLDILKKKYDAEKEKITTEIAKIEQEKKQRIAELEEETRTW 894

Query: 497 NVKDLIEKLKSAE-EQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNK 555
             +    + +  + E+I +L   I   +  + KV+S  K    ++      ++KV  +NK
Sbjct: 895 EDRYNNREARPEDLEKIQKLEALIAERSAAIEKVQSELKRYQAELLNRETTYNKVF-NNK 953

Query: 556 EIVRLTEELHHLSQKVAELEEEKGNLQLHLV--DYDSGR 592
             V +   L   +++ A +       +L  V   +DS R
Sbjct: 954 PQVNVLSALERKARRDAIIAAANSTSKLPPVKDSHDSAR 992


>UniRef50_Q4D6G7 Cluster: Putative uncharacterized protein; n=4;
            Trypanosoma cruzi|Rep: Putative uncharacterized protein -
            Trypanosoma cruzi
          Length = 2493

 Score =  125 bits (301), Expect = 1e-26
 Identities = 249/1481 (16%), Positives = 586/1481 (39%), Gaps = 105/1481 (7%)

Query: 144  VTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXX 203
            V  L   ++E+D+AL+ L  +++        L+ + +E    + A  +            
Sbjct: 699  VVTLRRQLQERDDALAALNDRLEEHSREKSALESRTSESVDALAAMERQLQERDDALAAL 758

Query: 204  XXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAA 263
                    +D  ++ ++ +    +  +E  D    + + ++ +D  +++L++  +L E  
Sbjct: 759  --------KDRLEEHSREKSALESRTSESVDALAAMERQLQERDDALAALKD--RLEEYG 808

Query: 264  RFEISLEHSKLAQELEQXXXXXXXXXXXXXXLA--KQSIEPSCEEKTEIEEKGSLEIANM 321
            R + +LE S+ ++ ++               LA  K  +E    EK+ +E + S  +  +
Sbjct: 809  REKSALE-SRTSESVDAVVTLSRQLQERDDALAALKDRLEEHSREKSALESRTSESVDAL 867

Query: 322  TELTKKIELLEHLNCQIRQTNKEL-ENKLATMGTESKAVSSP-------SKKGSPLISRK 373
              + ++++  +     ++   +E    K A     S++V +         ++   L +  
Sbjct: 868  AAMERQLQERDDALAALKDRLEEYGREKSALESRTSESVDAVVTLRRQLQERDDALAALN 927

Query: 374  SGRNTASKMKSPWSQLSSETLN----QDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVIS 429
                  S+ KS     +SE+++     +   +   + +A L+  ++  +++    E   S
Sbjct: 928  DRLEEHSREKSALESRTSESVDALAAMERQPQERDDALAALKDRLEEYSREKSALESRTS 987

Query: 430  EKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQE- 488
            E              +D  +A L+   +++    S +   T+ E V+ +A ++ QL++  
Sbjct: 988  ESVDAVVTLRRQLQERDDALAALKDRLEEYSREKSALESRTS-ESVDALAAMERQLQERD 1046

Query: 489  -----LNDEIKDVN-VKDLIEKLKS-------AEEQITQLNDEIDAANKNMIKVKSNHKL 535
                 LND +++ +  K  +E   S       A E+  Q  D+  AA K+ ++  S  K 
Sbjct: 1047 DALAALNDRLEEYSREKSALESRTSESVDALAAMERRLQERDDALAALKDRLEEYSREKS 1106

Query: 536  KLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVD-YDSGRMI 594
             L+   +T ++   ++   +++    + L  L+ ++ E   EK  L+    +  D+   +
Sbjct: 1107 ALES--RTSESVGALAAMERQLQERDDALAALNDRLEEYGREKSALESRTSESVDAVVTL 1164

Query: 595  ESDVYKK---MIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADIS-QL 650
               + ++   +  +++  E   +  S LES+  + V  L  ++++  E +D LA ++ +L
Sbjct: 1165 RRQLQERDDALAALKDRLEEHSREKSALESRTSESVDALAAMERQLQERDDALAALNDRL 1224

Query: 651  QSDQVCSEIKSVHLEEQIDALSASKKEL-----ALVIENLKLDK-EQLYGTIKDLENDKE 704
            +              E +DAL+A +++      AL   N +L++  +    ++   ++  
Sbjct: 1225 EEHSREKSALESRTSESVDALAAMERQPQERDDALAALNDRLEEYSREKSALESRTSESV 1284

Query: 705  DIMNKLQNYIQENMD----LTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQER 760
            D +  L+  +QE  D    L D+LE+ S EK     + +       +     +  ++QER
Sbjct: 1285 DAVVTLRRQLQERDDALAALKDRLEEHSREK-----SALESRTSESVDAVVTLRRQLQER 1339

Query: 761  DLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQE 820
            D  +  ++  L +Y      LE   +       ++ER+  +    L        EY  ++
Sbjct: 1340 DDALAALKDRLEEYSREKSALESRTSESVGALAAMERQLQERDDALAALNDRLEEYGREK 1399

Query: 821  DELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALV 880
              L +R +  +D    + +QL E +     L+ + +    E   L+   S+      A+ 
Sbjct: 1400 SALESRTSESVDAVVTLRRQLQERDDALAALKDRLEEYGREKSALESRTSESVDALAAME 1459

Query: 881  EKAN-RTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKK--EIEDLEIEFNTQIE 937
             +   R D   +   + +   R+  +   R +     L   +++  E +D     N ++E
Sbjct: 1460 RQLQERDDALAALKDRLEEHSREKSALESRTSESVDALAAMERQLQERDDALAALNDRLE 1519

Query: 938  SAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQ 997
               R+K  L  +  ++++ +  +E QLQE  + +  L   +EE ++          +K  
Sbjct: 1520 EHSREKSALESRTSESVDALAAMERQLQERDDALAALKDRLEEYSR----------EKSA 1569

Query: 998  TQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKL 1057
             +S   T + ++ +  L   L+++D+ + AL  ++      Y    S  ES+ ++    L
Sbjct: 1570 LESR--TSESVDAVVTLRRQLQERDDALAALKDRLEE----YSREKSALESRTSESVGAL 1623

Query: 1058 ENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISST 1117
              ME ++Q     L       EE        + +  E  +  +T    + + +  + +  
Sbjct: 1624 AAMERQLQERDDALAALNDRLEEYDREKSALESRTSESVDAVVTLRRQLQERDDALAALN 1683

Query: 1118 IEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQ 1177
             + + +                  L   E +  +QER    +  A L   L+E   +   
Sbjct: 1684 -DRLEEYGREKSALESRTSGSVDALAAMERQ--LQERD---DALAALKDRLEEYGREKSA 1737

Query: 1178 LETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAE 1237
            LE+  +E     V  + Q+ +    L  LN   +      + L S  S +VD       +
Sbjct: 1738 LESRTSESVDAVVTLRRQLQERDDALAALNDRLEEYGREKSALESRTSESVDALAAMERQ 1797

Query: 1238 LWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQN 1297
            L ++  A      +  EH    + S  ES+  + +D++ +  ++   +    + + +L++
Sbjct: 1798 LQERDDALAALKDRLEEHSR--EKSVLESRTSESVDALAAMERQLQERD---DALAALKD 1852

Query: 1298 KLQDKEEHLRNLQEKYADVINQIEILRSEIE--DEKVAFXXXXXXXXXXXXXXXXDLRTE 1355
            +L++       L+ + ++ ++ +  LR +++  D+ +A                    +E
Sbjct: 1853 RLEEHSREKSALESRTSESVDAVVTLRRQLQERDDALAALKDRLEEYGREKSALESRTSE 1912

Query: 1356 NQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKD-- 1413
            +        + +   ++  A LK               R +++   +  +  QL+ +D  
Sbjct: 1913 SVDAVVTLRRQLQERDDALAALKDRLEEYSREKSALESRTSESVDALAAMERQLQERDDA 1972

Query: 1414 -SEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANH 1472
             + +  K  EY     +     E+   + V+    +     E++  LA L  ++ E++  
Sbjct: 1973 LAALKDKLEEYG----REKSALESRTSESVDAVVTLRRQLQERDDALAALNDRLEEHSRE 2028

Query: 1473 YETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIE 1532
               ++  +  E V  +  +  ++ E    +  +A LN  LEE   + + +++        
Sbjct: 2029 KSALESRTS-ESVDALAAMERQLQER---DDALAALNDKLEEYGREKSALESRTSESVDA 2084

Query: 1533 IVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLD 1573
            +VTL  ++    + + A + ++++H    S  +    E +D
Sbjct: 2085 VVTLRRQLQERDDALAALNDRLEEHSREKSALESRTSESVD 2125



 Score =  115 bits (276), Expect = 1e-23
 Identities = 274/1508 (18%), Positives = 599/1508 (39%), Gaps = 123/1508 (8%)

Query: 147  LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXX 206
            L++ ++E     SVL+ +       ++ L+ ++ E+D  + A                  
Sbjct: 576  LNDKLEEYGREKSVLESRTSESVDVVVTLERQLQERDDALAALKDRLEEHSREKSVLESR 635

Query: 207  XXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFE 266
                 +       ++QE+  A+ A        + + ++ +D  +++L++  +L E  R +
Sbjct: 636  TSESVDVVVTLERQLQESVDALAA--------MERQLQERDDALAALKD--RLEEYGREK 685

Query: 267  ISLEHSKLAQELEQXXXXXXXXXXXXXXLA--KQSIEPSCEEKTEIEEKGSLEI----AN 320
             +LE S+ ++ ++               LA     +E    EK+ +E + S  +    A 
Sbjct: 686  SALE-SRTSESVDAVVTLRRQLQERDDALAALNDRLEEHSREKSALESRTSESVDALAAM 744

Query: 321  MTELTKKIELLEHLNCQIRQTNKE---LENKLATMGTESKAVSSP-SKKGSPLISRKSGR 376
              +L ++ + L  L  ++ + ++E   LE++ +       A+     ++   L + K   
Sbjct: 745  ERQLQERDDALAALKDRLEEHSREKSALESRTSESVDALAAMERQLQERDDALAALKDRL 804

Query: 377  NTASKMKSPWSQLSSETLNQ--DTDKKINKNE--IAKLEMVIQSLNKDLVDKEYVISEKD 432
                + KS     +SE+++      +++ + +  +A L+  ++  +++    E   SE  
Sbjct: 805  EEYGREKSALESRTSESVDAVVTLSRQLQERDDALAALKDRLEEHSREKSALESRTSESV 864

Query: 433  TXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQE---- 488
                        +D  +A L+   +++    S +   T +E V+ +  ++ QL++     
Sbjct: 865  DALAAMERQLQERDDALAALKDRLEEYGREKSALESRT-SESVDAVVTLRRQLQERDDAL 923

Query: 489  --LNDEIKD-VNVKDLIEKLKS-------AEEQITQLNDEIDAANKNMIKVKSNHKLKLK 538
              LND +++    K  +E   S       A E+  Q  D+  AA K+ ++  S  K  L+
Sbjct: 924  AALNDRLEEHSREKSALESRTSESVDALAAMERQPQERDDALAALKDRLEEYSREKSALE 983

Query: 539  QMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVD-YDSGRMIESD 597
               +T ++   V    +++    + L  L  ++ E   EK  L+    +  D+   +E  
Sbjct: 984  --SRTSESVDAVVTLRRQLQERDDALAALKDRLEEYSREKSALESRTSESVDALAAMERQ 1041

Query: 598  VYKK---MIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADI-SQLQSD 653
            + ++   +  + +  E   +  S LES+  + V  L  ++++  E +D LA +  +L+  
Sbjct: 1042 LQERDDALAALNDRLEEYSREKSALESRTSESVDALAAMERRLQERDDALAALKDRLEEY 1101

Query: 654  QVCSEIKSVHLEEQIDALSASKKELALVIENLKL--DKEQLYGTIKD-LE---NDKEDIM 707
                        E + AL+A +++L    + L    D+ + YG  K  LE   ++  D +
Sbjct: 1102 SREKSALESRTSESVGALAAMERQLQERDDALAALNDRLEEYGREKSALESRTSESVDAV 1161

Query: 708  NKLQNYIQENMD----LTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLY 763
              L+  +QE  D    L D+LE+ S EK     + +       +     ++ ++QERD  
Sbjct: 1162 VTLRRQLQERDDALAALKDRLEEHSREK-----SALESRTSESVDALAAMERQLQERDDA 1216

Query: 764  IENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDEL 823
            +  +   L ++      LE   +   D   ++ER+  +    L        EY+ ++  L
Sbjct: 1217 LAALNDRLEEHSREKSALESRTSESVDALAAMERQPQERDDALAALNDRLEEYSREKSAL 1276

Query: 824  VNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEK- 882
             +R +  +D    + +QL E +     L+ + +    E   L+   S+       L  + 
Sbjct: 1277 ESRTSESVDAVVTLRRQLQERDDALAALKDRLEEHSREKSALESRTSESVDAVVTLRRQL 1336

Query: 883  ANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKK--KEIEDLEIEFNTQIESAI 940
              R D   +   + +   R+  +   R +     L   ++  +E +D     N ++E   
Sbjct: 1337 QERDDALAALKDRLEEYSREKSALESRTSESVGALAAMERQLQERDDALAALNDRLEEYG 1396

Query: 941  RDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQS 1000
            R+K  L  +  ++++ V  L  QLQE  + +  L   +EE  +    L  +    +   +
Sbjct: 1397 REKSALESRTSESVDAVVTLRRQLQERDDALAALKDRLEEYGREKSALESR--TSESVDA 1454

Query: 1001 PDYTEQYINEINKLNALLKQKDE----EIIALNQKINNAQVSYMSM---VSDYESKLAQF 1053
                E+ + E +   A LK + E    E  AL  + + +  +  +M   + + +  LA  
Sbjct: 1455 LAAMERQLQERDDALAALKDRLEEHSREKSALESRTSESVDALAAMERQLQERDDALAAL 1514

Query: 1054 TTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMI 1113
              +LE    E   +  +  +S      ++  ++E+DD +  LK+    +     + +  +
Sbjct: 1515 NDRLEEHSREKSALESRTSESVDALAAMERQLQERDDALAALKDRLEEYS----REKSAL 1570

Query: 1114 ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQS-------AKLNT 1166
             S T E + D    +             LK    EE+ +E+S L+ ++       A +  
Sbjct: 1571 ESRTSESV-DAVVTLRRQLQERDDALAALK-DRLEEYSREKSALESRTSESVGALAAMER 1628

Query: 1167 ELQECYTKII----QLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNL--LSTVAEL 1220
            +LQE    +     +LE  + E +  +    E ++ + +   QL   +D L  L+   E 
Sbjct: 1629 QLQERDDALAALNDRLEEYDREKSALESRTSESVDAVVTLRRQLQERDDALAALNDRLEE 1688

Query: 1221 RSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQ 1280
                 SA++ R     +     LA  E   Q+ +  L       E +Y +   +++S T 
Sbjct: 1689 YGREKSALESRTSGSVDA----LAAMERQLQERDDALAALKDRLE-EYGREKSALESRTS 1743

Query: 1281 EETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIED--EKVAFXXXX 1338
            E  + +VT      L+ +LQ++++ L  L ++  +   +   L S   +  + +A     
Sbjct: 1744 ESVDAVVT------LRRQLQERDDALAALNDRLEEYGREKSALESRTSESVDALAAMERQ 1797

Query: 1339 XXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDA 1398
                        D   E+   K + E       +  A +++              R+ + 
Sbjct: 1798 LQERDDALAALKDRLEEHSREKSVLESRTSESVDALAAMERQLQERDDALAALKDRLEEH 1857

Query: 1399 EAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEY---EKRIEDLTYEK 1455
              +       LE + SE           L +R+D    ++ +L EY   +  +E  T E 
Sbjct: 1858 SRE----KSALESRTSESVDAVVTLRRQLQERDDALAALKDRLEEYGREKSALESRTSES 1913

Query: 1456 ESELAILRLKMHENANHYETMQ---KESEIERVKLIEELNVKITESVSLNKQVAELN--- 1509
               +  LR ++ E  +    ++   +E   E+  L    +  +    ++ +Q+ E +   
Sbjct: 1914 VDAVVTLRRQLQERDDALAALKDRLEEYSREKSALESRTSESVDALAAMERQLQERDDAL 1973

Query: 1510 KALEEEVAKTNEMQTALENQEIE----IVTLNDEITNLQNMVRASSSKIQKHVSFASDTK 1565
             AL++++ +    ++ALE++  E    +VTL  ++    + + A + ++++H    S  +
Sbjct: 1974 AALKDKLEEYGREKSALESRTSESVDAVVTLRRQLQERDDALAALNDRLEEHSREKSALE 2033

Query: 1566 QGRDEQLD 1573
                E +D
Sbjct: 2034 SRTSESVD 2041



 Score =  114 bits (274), Expect = 2e-23
 Identities = 236/1332 (17%), Positives = 527/1332 (39%), Gaps = 104/1332 (7%)

Query: 298  QSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESK 357
            Q I  + EEK +++++  + I   ++   + +L + L+ +I    +E  N+ A   T  K
Sbjct: 464  QQIRKNAEEKLQLQQR--ILINTRSKNMGETQLRQKLSQEIDTKEREDNNRNAKTFTRIK 521

Query: 358  AVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNE--IAKLEMVIQ 415
               +     +P + R+   +   K       +    +    ++++ + +  +A L   ++
Sbjct: 522  HFYTQDSPRTPPVQRRLDFSGKEKHLLKDCPIKGFDVLATLERQLQERDDALAALNDKLE 581

Query: 416  SLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDV 475
               ++    E   SE              +D  +A L+   ++H    S++   T+ E V
Sbjct: 582  EYGREKSVLESRTSESVDVVVTLERQLQERDDALAALKDRLEEHSREKSVLESRTS-ESV 640

Query: 476  NEIAKVQEQLKQELN---------DEIKDV--NVKDLIEKL---KSAEEQIT-------- 513
            + +  ++ QL++ ++          E  D    +KD +E+    KSA E  T        
Sbjct: 641  DVVVTLERQLQESVDALAAMERQLQERDDALAALKDRLEEYGREKSALESRTSESVDAVV 700

Query: 514  ----QLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQ 569
                QL +  DA      +++ + + K     +T ++   ++   +++    + L  L  
Sbjct: 701  TLRRQLQERDDALAALNDRLEEHSREKSALESRTSESVDALAAMERQLQERDDALAALKD 760

Query: 570  KVAELEEEKGNLQLHLVD-YDSGRMIESDVYKK---MIEMENLAETRLKAISLLESQKFD 625
            ++ E   EK  L+    +  D+   +E  + ++   +  +++  E   +  S LES+  +
Sbjct: 761  RLEEHSREKSALESRTSESVDALAAMERQLQERDDALAALKDRLEEYGREKSALESRTSE 820

Query: 626  LVQELHILQQKYDEVEDKLADIS-QLQSDQVCSEIKSVHLEEQIDALSASKKELALVIEN 684
             V  +  L ++  E +D LA +  +L+              E +DAL+A +++L    + 
Sbjct: 821  SVDAVVTLSRQLQERDDALAALKDRLEEHSREKSALESRTSESVDALAAMERQLQERDDA 880

Query: 685  LKLDKEQL--YGTIKD-LEN---DKEDIMNKLQNYIQENMD----LTDKLEKMSAEKISE 734
            L   K++L  YG  K  LE+   +  D +  L+  +QE  D    L D+LE+ S EK   
Sbjct: 881  LAALKDRLEEYGREKSALESRTSESVDAVVTLRRQLQERDDALAALNDRLEEHSREK--- 937

Query: 735  LLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYS 794
              + +       +     ++ + QERD  +  ++  L +Y      LE   +   D   +
Sbjct: 938  --SALESRTSESVDALAAMERQPQERDDALAALKDRLEEYSREKSALESRTSESVDAVVT 995

Query: 795  LERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKK 854
            L R+  +    L   +    EY+ ++  L +R +  +D    +E+QL E +     L  +
Sbjct: 996  LRRQLQERDDALAALKDRLEEYSREKSALESRTSESVDALAAMERQLQERDDALAALNDR 1055

Query: 855  NQILLEENQNLQISLSDMQQHYNALVEK-ANRTDLAESESTKYQTQLRDLESNLKRITHE 913
             +    E   L+   S+      A+  +   R D   +   + +   R+  +   R +  
Sbjct: 1056 LEEYSREKSALESRTSESVDALAAMERRLQERDDALAALKDRLEEYSREKSALESRTSES 1115

Query: 914  HQTLIVQKK--KEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNI 971
               L   ++  +E +D     N ++E   R+K  L  +  ++++ V  L  QLQE  + +
Sbjct: 1116 VGALAAMERQLQERDDALAALNDRLEEYGREKSALESRTSESVDAVVTLRRQLQERDDAL 1175

Query: 972  ENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQK 1031
              L   +EE ++          +K   +S   T + ++ +  +   L+++D+ + ALN +
Sbjct: 1176 AALKDRLEEHSR----------EKSALES--RTSESVDALAAMERQLQERDDALAALNDR 1223

Query: 1032 INNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQ 1091
            +      +    S  ES+ ++    L  ME + Q     L       EE        + +
Sbjct: 1224 LE----EHSREKSALESRTSESVDALAAMERQPQERDDALAALNDRLEEYSREKSALESR 1279

Query: 1092 IKELKETKLTFEMNIPKTEGMI--ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEE 1149
              E  +  +T    + + +  +  +   +E  S + + ++            L+ Q    
Sbjct: 1280 TSESVDAVVTLRRQLQERDDALAALKDRLEEHSREKSALESRTSESVDAVVTLRRQ---- 1335

Query: 1150 FIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTE 1209
             +QER    +  A L   L+E   +   LE+  +E  G     + Q+ +    L  LN  
Sbjct: 1336 -LQER---DDALAALKDRLEEYSREKSALESRTSESVGALAAMERQLQERDDALAALNDR 1391

Query: 1210 NDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQRE---ADFQKTEHELRVQLSAFES 1266
             +      + L S  S +VD     +  L +Q L +R+   A  +    E   + SA ES
Sbjct: 1392 LEEYGREKSALESRTSESVD----AVVTLRRQ-LQERDDALAALKDRLEEYGREKSALES 1446

Query: 1267 KYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSE 1326
            +  + +D++ +  ++   +    + + +L+++L++       L+ + ++ ++ +  +  +
Sbjct: 1447 RTSESVDALAAMERQLQER---DDALAALKDRLEEHSREKSALESRTSESVDALAAMERQ 1503

Query: 1327 IE--DEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXX 1384
            ++  D+ +A                    +E+       E+ +   ++  A LK      
Sbjct: 1504 LQERDDALAALNDRLEEHSREKSALESRTSESVDALAAMERQLQERDDALAALKDRLEEY 1563

Query: 1385 XXXXXXXXXRVNDAEAKVLELTHQLELKD---SEIYQKTHEYTITLTQRNDEFENVRQQL 1441
                     R +++   V+ L  QL+ +D   + +  +  EY    ++     E+   + 
Sbjct: 1564 SREKSALESRTSESVDAVVTLRRQLQERDDALAALKDRLEEY----SREKSALESRTSES 1619

Query: 1442 VEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSL 1501
            V     +E    E++  LA L  ++ E       ++  +  E V  +  L  ++ E    
Sbjct: 1620 VGALAAMERQLQERDDALAALNDRLEEYDREKSALESRTS-ESVDAVVTLRRQLQER--- 1675

Query: 1502 NKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFA 1561
            +  +A LN  LEE   + + +++        +  +  ++    + + A   +++++    
Sbjct: 1676 DDALAALNDRLEEYGREKSALESRTSGSVDALAAMERQLQERDDALAALKDRLEEYGREK 1735

Query: 1562 SDTKQGRDEQLD 1573
            S  +    E +D
Sbjct: 1736 SALESRTSESVD 1747



 Score = 97.5 bits (232), Expect = 3e-18
 Identities = 183/989 (18%), Positives = 418/989 (42%), Gaps = 85/989 (8%)

Query: 147  LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXX 206
            L +   E  +AL+ ++ +++  +  +  L +++ E  +   A    T+            
Sbjct: 1192 LESRTSESVDALAAMERQLQERDDALAALNDRLEEHSREKSALESRTSESVDALAAMERQ 1251

Query: 207  ------XXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLL 260
                        D  ++ ++ +    +  +E  D    L + ++ +D  +++L++  +L 
Sbjct: 1252 PQERDDALAALNDRLEEYSREKSALESRTSESVDAVVTLRRQLQERDDALAALKD--RLE 1309

Query: 261  EAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLA--KQSIEPSCEEKTEIEEKGSLEI 318
            E +R + +LE S+ ++ ++               LA  K  +E    EK+ +E + S  +
Sbjct: 1310 EHSREKSALE-SRTSESVDAVVTLRRQLQERDDALAALKDRLEEYSREKSALESRTSESV 1368

Query: 319  ANMTELTKKIE----LLEHLNCQIRQTNKELENKLATMGTES-KAVSSPSK----KGSPL 369
              +  + ++++     L  LN ++ +  +E ++ L +  +ES  AV +  +    +   L
Sbjct: 1369 GALAAMERQLQERDDALAALNDRLEEYGRE-KSALESRTSESVDAVVTLRRQLQERDDAL 1427

Query: 370  ISRKSGRNTASKMKSPWSQLSSETLNQ--DTDKKINKNE--IAKLEMVIQSLNKDLVDKE 425
             + K       + KS     +SE+++     ++++ + +  +A L+  ++  +++    E
Sbjct: 1428 AALKDRLEEYGREKSALESRTSESVDALAAMERQLQERDDALAALKDRLEEHSREKSALE 1487

Query: 426  YVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQL 485
               SE              +D  +A L    ++H    S +   T+ E V+ +A ++ QL
Sbjct: 1488 SRTSESVDALAAMERQLQERDDALAALNDRLEEHSREKSALESRTS-ESVDALAAMERQL 1546

Query: 486  KQE------LNDEIKDVN-VKDLIEKL--KSAEEQIT-----QLNDEIDAANKNMIKVKS 531
            ++       L D +++ +  K  +E    +S +  +T     Q  D+  AA K+ ++  S
Sbjct: 1547 QERDDALAALKDRLEEYSREKSALESRTSESVDAVVTLRRQLQERDDALAALKDRLEEYS 1606

Query: 532  NHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVD-YDS 590
              K  L+   +T ++   ++   +++    + L  L+ ++ E + EK  L+    +  D+
Sbjct: 1607 REKSALES--RTSESVGALAAMERQLQERDDALAALNDRLEEYDREKSALESRTSESVDA 1664

Query: 591  GRMIESDVYKK---MIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADI 647
               +   + ++   +  + +  E   +  S LES+    V  L  ++++  E +D LA +
Sbjct: 1665 VVTLRRQLQERDDALAALNDRLEEYGREKSALESRTSGSVDALAAMERQLQERDDALAAL 1724

Query: 648  SQLQSD--QVCSEIKSVHLEEQIDALSASKKELALVIENLKL--DKEQLYGTIKD-LEN- 701
                 +  +  S ++S    E +DA+   +++L    + L    D+ + YG  K  LE+ 
Sbjct: 1725 KDRLEEYGREKSALES-RTSESVDAVVTLRRQLQERDDALAALNDRLEEYGREKSALESR 1783

Query: 702  --DKEDIMNKLQNYIQENMD----LTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDA 755
              +  D +  ++  +QE  D    L D+LE+ S EK     + +       +     ++ 
Sbjct: 1784 TSESVDALAAMERQLQERDDALAALKDRLEEHSREK-----SVLESRTSESVDALAAMER 1838

Query: 756  KIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSE 815
            ++QERD  +  ++  L ++      LE   +   D   +L R+  +    L   +    E
Sbjct: 1839 QLQERDDALAALKDRLEEHSREKSALESRTSESVDAVVTLRRQLQERDDALAALKDRLEE 1898

Query: 816  YTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQH 875
            Y  ++  L +R +  +D    + +QL E +     L+ + +    E   L+   S+    
Sbjct: 1899 YGREKSALESRTSESVDAVVTLRRQLQERDDALAALKDRLEEYSREKSALESRTSESVDA 1958

Query: 876  YNALVEKAN-RTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLE---IE 931
              A+  +   R D   +   K +   R+ +S L+  T E    +V  ++++++ +     
Sbjct: 1959 LAAMERQLQERDDALAALKDKLEEYGRE-KSALESRTSESVDAVVTLRRQLQERDDALAA 2017

Query: 932  FNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDK 991
             N ++E   R+K  L  +  ++++ +  +E QLQE  + +  LN  +EE  +        
Sbjct: 2018 LNDRLEEHSREKSALESRTSESVDALAAMERQLQERDDALAALNDKLEEYGR-------- 2069

Query: 992  HVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLA 1051
              +K   +S   T + ++ +  L   L+++D+ + ALN ++      +    S  ES+ +
Sbjct: 2070 --EKSALES--RTSESVDAVVTLRRQLQERDDALAALNDRLE----EHSREKSALESRTS 2121

Query: 1052 QFTTKLENMEEEMQRVSKQLLDSKQHNEE 1080
            +    L  ME ++Q     L   K   EE
Sbjct: 2122 ESVDALAAMERQLQERDDALAALKDRLEE 2150



 Score = 92.7 bits (220), Expect = 8e-17
 Identities = 182/1007 (18%), Positives = 413/1007 (41%), Gaps = 74/1007 (7%)

Query: 144  VTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXX 203
            V  L   ++E+D+AL+ L+ +++        L+ + +E    + A  +            
Sbjct: 1161 VVTLRRQLQERDDALAALKDRLEEHSREKSALESRTSESVDALAAMERQLQERDDALAAL 1220

Query: 204  XXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAA 263
                     +     ++  E+  A+ A  +  ++R        D  +++L +  +L E +
Sbjct: 1221 NDRLEEHSREKSALESRTSESVDALAAMERQPQER--------DDALAALND--RLEEYS 1270

Query: 264  RFEISLEHSKLAQELEQXXXXXXXXXXXXXXLA--KQSIEPSCEEKTEIEEKGSLEIANM 321
            R + +LE S+ ++ ++               LA  K  +E    EK+ +E + S  +  +
Sbjct: 1271 REKSALE-SRTSESVDAVVTLRRQLQERDDALAALKDRLEEHSREKSALESRTSESVDAV 1329

Query: 322  TELTKKIE----LLEHLNCQIRQTNKE---LENKLA-TMGTESKAVSSPSKKGSPLISRK 373
              L ++++     L  L  ++ + ++E   LE++ + ++G  +       ++   L +  
Sbjct: 1330 VTLRRQLQERDDALAALKDRLEEYSREKSALESRTSESVGALAAMERQLQERDDALAALN 1389

Query: 374  SGRNTASKMKSPWSQLSSETLNQDTDKKINKNE----IAKLEMVIQSLNKDLVDKEYVIS 429
                   + KS     +SE+++     +    E    +A L+  ++   ++    E   S
Sbjct: 1390 DRLEEYGREKSALESRTSESVDAVVTLRRQLQERDDALAALKDRLEEYGREKSALESRTS 1449

Query: 430  EKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQE- 488
            E              +D  +A L+   ++H    S +   T+ E V+ +A ++ QL++  
Sbjct: 1450 ESVDALAAMERQLQERDDALAALKDRLEEHSREKSALESRTS-ESVDALAAMERQLQERD 1508

Query: 489  -----LNDEIKDVN---------VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHK 534
                 LND +++ +           + ++ L + E Q+ + +D + AA K+ ++  S  K
Sbjct: 1509 DALAALNDRLEEHSREKSALESRTSESVDALAAMERQLQERDDAL-AALKDRLEEYSREK 1567

Query: 535  LKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSG-RM 593
              L+   +T ++   V    +++    + L  L  ++ E   EK  L+    +       
Sbjct: 1568 SALES--RTSESVDAVVTLRRQLQERDDALAALKDRLEEYSREKSALESRTSESVGALAA 1625

Query: 594  IESDVYKK---MIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQL 650
            +E  + ++   +  + +  E   +  S LES+  + V  +  L+++  E +D LA ++  
Sbjct: 1626 MERQLQERDDALAALNDRLEEYDREKSALESRTSESVDAVVTLRRQLQERDDALAALNDR 1685

Query: 651  QSD--QVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQL--YGTIKD-LEN---D 702
              +  +  S ++S      +DAL+A +++L    + L   K++L  YG  K  LE+   +
Sbjct: 1686 LEEYGREKSALES-RTSGSVDALAAMERQLQERDDALAALKDRLEEYGREKSALESRTSE 1744

Query: 703  KEDIMNKLQNYIQENMD----LTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQ 758
              D +  L+  +QE  D    L D+LE+   EK     + +       +     ++ ++Q
Sbjct: 1745 SVDAVVTLRRQLQERDDALAALNDRLEEYGREK-----SALESRTSESVDALAAMERQLQ 1799

Query: 759  ERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTI 818
            ERD  +  ++  L ++      LE   +   D   ++ER+  +    L   +    E++ 
Sbjct: 1800 ERDDALAALKDRLEEHSREKSVLESRTSESVDALAAMERQLQERDDALAALKDRLEEHSR 1859

Query: 819  QEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNA 878
            ++  L +R +  +D    + +QL E +     L+ + +    E   L+   S+       
Sbjct: 1860 EKSALESRTSESVDAVVTLRRQLQERDDALAALKDRLEEYGREKSALESRTSESVDAVVT 1919

Query: 879  LVEKAN-RTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKK--EIEDLEIEFNTQ 935
            L  +   R D   +   + +   R+  +   R +     L   +++  E +D       +
Sbjct: 1920 LRRQLQERDDALAALKDRLEEYSREKSALESRTSESVDALAAMERQLQERDDALAALKDK 1979

Query: 936  IESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQK 995
            +E   R+K  L  +  ++++ V  L  QLQE  + +  LN  +EE ++    L  +  + 
Sbjct: 1980 LEEYGREKSALESRTSESVDAVVTLRRQLQERDDALAALNDRLEEHSREKSALESRTSES 2039

Query: 996  QQTQSP--DYTEQYINEINKLNALLKQKDEEIIALNQKIN---NAQVSYMSMVSDYESKL 1050
                +      ++  + +  LN  L++   E  AL  + +   +A V+    + + +  L
Sbjct: 2040 VDALAAMERQLQERDDALAALNDKLEEYGREKSALESRTSESVDAVVTLRRQLQERDDAL 2099

Query: 1051 AQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKE 1097
            A    +LE    E   +  +  +S      ++  ++E+DD +  LK+
Sbjct: 2100 AALNDRLEEHSREKSALESRTSESVDALAAMERQLQERDDALAALKD 2146



 Score = 88.6 bits (210), Expect = 1e-15
 Identities = 164/885 (18%), Positives = 363/885 (41%), Gaps = 67/885 (7%)

Query: 144  VTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXX 203
            V  L   ++E+D+AL+ L+ +++        L+ + +E    + A  +            
Sbjct: 1329 VVTLRRQLQERDDALAALKDRLEEYSREKSALESRTSESVGALAAMERQLQERDDALAAL 1388

Query: 204  XXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAA 263
                     D  ++  + +    +  +E  D    L + ++ +D  +++L++  +L E  
Sbjct: 1389 --------NDRLEEYGREKSALESRTSESVDAVVTLRRQLQERDDALAALKD--RLEEYG 1438

Query: 264  RFEISLEHSKLAQELEQXXXXXXXXXXXXXXLA--KQSIEPSCEEKTEIEEKGSLEI--- 318
            R + +LE S+ ++ ++               LA  K  +E    EK+ +E + S  +   
Sbjct: 1439 REKSALE-SRTSESVDALAAMERQLQERDDALAALKDRLEEHSREKSALESRTSESVDAL 1497

Query: 319  -ANMTELTKKIELLEHLNCQIRQTNKE---LENKLATMGTESKAVSSP-SKKGSPLISRK 373
             A   +L ++ + L  LN ++ + ++E   LE++ +       A+     ++   L + K
Sbjct: 1498 AAMERQLQERDDALAALNDRLEEHSREKSALESRTSESVDALAAMERQLQERDDALAALK 1557

Query: 374  SGRNTASKMKSPWSQLSSETLNQDTDKKINKNE----IAKLEMVIQSLNKDLVDKEYVIS 429
                  S+ KS     +SE+++     +    E    +A L+  ++  +++    E   S
Sbjct: 1558 DRLEEYSREKSALESRTSESVDAVVTLRRQLQERDDALAALKDRLEEYSREKSALESRTS 1617

Query: 430  EKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQE- 488
            E              +D  +A L    +++    S +   T+ E V+ +  ++ QL++  
Sbjct: 1618 ESVGALAAMERQLQERDDALAALNDRLEEYDREKSALESRTS-ESVDAVVTLRRQLQERD 1676

Query: 489  -----LNDEIKDVN---------VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHK 534
                 LND +++               ++ L + E Q+ + +D + AA K+ ++     K
Sbjct: 1677 DALAALNDRLEEYGREKSALESRTSGSVDALAAMERQLQERDDAL-AALKDRLEEYGREK 1735

Query: 535  LKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVD-YDSGRM 593
              L+   +T ++   V    +++    + L  L+ ++ E   EK  L+    +  D+   
Sbjct: 1736 SALES--RTSESVDAVVTLRRQLQERDDALAALNDRLEEYGREKSALESRTSESVDALAA 1793

Query: 594  IESDVYKK---MIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADIS-Q 649
            +E  + ++   +  +++  E   +  S+LES+  + V  L  ++++  E +D LA +  +
Sbjct: 1794 MERQLQERDDALAALKDRLEEHSREKSVLESRTSESVDALAAMERQLQERDDALAALKDR 1853

Query: 650  LQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQL--YGTIKD-LEN---DK 703
            L+              E +DA+   +++L    + L   K++L  YG  K  LE+   + 
Sbjct: 1854 LEEHSREKSALESRTSESVDAVVTLRRQLQERDDALAALKDRLEEYGREKSALESRTSES 1913

Query: 704  EDIMNKLQNYIQENMD----LTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQE 759
             D +  L+  +QE  D    L D+LE+ S EK     + +       +     ++ ++QE
Sbjct: 1914 VDAVVTLRRQLQERDDALAALKDRLEEYSREK-----SALESRTSESVDALAAMERQLQE 1968

Query: 760  RDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQ 819
            RD  +  ++ +L +Y      LE   +   D   +L R+  +    L        E++ +
Sbjct: 1969 RDDALAALKDKLEEYGREKSALESRTSESVDAVVTLRRQLQERDDALAALNDRLEEHSRE 2028

Query: 820  EDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNAL 879
            +  L +R +  +D    +E+QL E +     L  K +    E   L+   S+       L
Sbjct: 2029 KSALESRTSESVDALAAMERQLQERDDALAALNDKLEEYGREKSALESRTSESVDAVVTL 2088

Query: 880  VEKAN-RTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKK--EIEDLEIEFNTQI 936
              +   R D   + + + +   R+  +   R +     L   +++  E +D       ++
Sbjct: 2089 RRQLQERDDALAALNDRLEEHSREKSALESRTSESVDALAAMERQLQERDDALAALKDRL 2148

Query: 937  ESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEEL 981
            E   R+K  L  +  ++++ +  +E QLQE  N     +  V E+
Sbjct: 2149 EEYGREKSALESRTSESVDALAAMERQLQERGNAFNIFDGRVNEI 2193



 Score = 84.6 bits (200), Expect = 2e-14
 Identities = 183/1086 (16%), Positives = 417/1086 (38%), Gaps = 76/1086 (6%)

Query: 497  NVKDLIEKLKSAEEQITQLNDEIDA-ANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNK 555
            N   + +K K   + ITQL    +  A    I+  +  KL+L+Q +  I+  SK     +
Sbjct: 435  NTHGVQQKRKPQRKTITQLQCAQNIKALVQQIRKNAEEKLQLQQ-RILINTRSKNMGETQ 493

Query: 556  EIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKA 615
               +L++E+    ++      +      H    DS R   +   ++ ++     +  LK 
Sbjct: 494  LRQKLSQEIDTKEREDNNRNAKTFTRIKHFYTQDSPR---TPPVQRRLDFSGKEKHLLKD 550

Query: 616  ISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASK 675
              +   + FD+   L  L+++  E +D LA ++    +      KSV     +++ ++  
Sbjct: 551  CPI---KGFDV---LATLERQLQERDDALAALNDKLEEY--GREKSV-----LESRTSES 597

Query: 676  KELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISEL 735
             ++ + +E    +++     +KD   +     + L++   E++D+   LE+   E +  L
Sbjct: 598  VDVVVTLERQLQERDDALAALKDRLEEHSREKSVLESRTSESVDVVVTLERQLQESVDAL 657

Query: 736  LAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSL 795
             A               ++ ++QERD  +  ++  L +Y      LE   +   D   +L
Sbjct: 658  AA---------------MERQLQERDDALAALKDRLEEYGREKSALESRTSESVDAVVTL 702

Query: 796  ERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKN 855
             R+  +    L        E++ ++  L +R +  +D    +E+QL E +     L+ + 
Sbjct: 703  RRQLQERDDALAALNDRLEEHSREKSALESRTSESVDALAAMERQLQERDDALAALKDRL 762

Query: 856  QILLEENQNLQISLSDMQQHYNALVEKANRTDLA----ESESTKYQTQLRDLESNLKRIT 911
            +    E   L+   S+      A+  +    D A    +    +Y  +   LES      
Sbjct: 763  EEHSREKSALESRTSESVDALAAMERQLQERDDALAALKDRLEEYGREKSALESRTSESV 822

Query: 912  HEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNI 971
                TL  ++ +E +D       ++E   R+K  L  +  ++++ +  +E QLQE  + +
Sbjct: 823  DAVVTL-SRQLQERDDALAALKDRLEEHSREKSALESRTSESVDALAAMERQLQERDDAL 881

Query: 972  ENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQK 1031
              L   +EE  +          +K   +S   T + ++ +  L   L+++D+ + ALN +
Sbjct: 882  AALKDRLEEYGR----------EKSALES--RTSESVDAVVTLRRQLQERDDALAALNDR 929

Query: 1032 INNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQ 1091
            +      +    S  ES+ ++    L  ME + Q     L   K   EE        + +
Sbjct: 930  LE----EHSREKSALESRTSESVDALAAMERQPQERDDALAALKDRLEEYSREKSALESR 985

Query: 1092 IKELKETKLTFEMNIPKTEGMI--ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEE 1149
              E  +  +T    + + +  +  +   +E  S + + ++            ++ Q    
Sbjct: 986  TSESVDAVVTLRRQLQERDDALAALKDRLEEYSREKSALESRTSESVDALAAMERQ---- 1041

Query: 1150 FIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTE 1209
             +QER    +  A LN  L+E   +   LE+  +E        + ++ +    L  L   
Sbjct: 1042 -LQER---DDALAALNDRLEEYSREKSALESRTSESVDALAAMERRLQERDDALAALKDR 1097

Query: 1210 NDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYE 1269
             +      + L S  S +V        E   Q      A       E   + SA ES+  
Sbjct: 1098 LEEYSREKSALESRTSESVG--ALAAMERQLQERDDALAALNDRLEEYGREKSALESRTS 1155

Query: 1270 QLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIE- 1328
            + +D+V +  ++   +    + + +L+++L++       L+ + ++ ++ +  +  +++ 
Sbjct: 1156 ESVDAVVTLRRQLQER---DDALAALKDRLEEHSREKSALESRTSESVDALAAMERQLQE 1212

Query: 1329 -DEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXX 1387
             D+ +A                    +E+       E+     ++  A L          
Sbjct: 1213 RDDALAALNDRLEEHSREKSALESRTSESVDALAAMERQPQERDDALAALNDRLEEYSRE 1272

Query: 1388 XXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKR 1447
                  R +++   V+ L  QL+ +D  +     +     ++     E+   + V+    
Sbjct: 1273 KSALESRTSESVDAVVTLRRQLQERDDAL-AALKDRLEEHSREKSALESRTSESVDAVVT 1331

Query: 1448 IEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAE 1507
            +     E++  LA L+ ++ E +     ++  +  E V  +  +  ++ E    +  +A 
Sbjct: 1332 LRRQLQERDDALAALKDRLEEYSREKSALESRTS-ESVGALAAMERQLQER---DDALAA 1387

Query: 1508 LNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQG 1567
            LN  LEE   + + +++        +VTL  ++    + + A   +++++    S  +  
Sbjct: 1388 LNDRLEEYGREKSALESRTSESVDAVVTLRRQLQERDDALAALKDRLEEYGREKSALESR 1447

Query: 1568 RDEQLD 1573
              E +D
Sbjct: 1448 TSESVD 1453



 Score = 82.2 bits (194), Expect = 1e-13
 Identities = 155/885 (17%), Positives = 359/885 (40%), Gaps = 55/885 (6%)

Query: 147  LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQ---IIEAKNKATTXXXXXXXXX 203
            L +   E  +A+  L+ +++  +  +  L++++ E  +    +E++   +          
Sbjct: 1276 LESRTSESVDAVVTLRRQLQERDDALAALKDRLEEHSREKSALESRTSESVDAVVTLRRQ 1335

Query: 204  XXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAA 263
                       K ++ +      A+E+   +    L         R  +L   N  LE  
Sbjct: 1336 LQERDDALAALKDRLEEYSREKSALESRTSESVGALAAMERQLQERDDALAALNDRLEEY 1395

Query: 264  RFEISLEHSKLAQELEQXXXXXXXXXXXXXXLA--KQSIEPSCEEKTEIEEKGSLEI--- 318
              E S   S+ ++ ++               LA  K  +E    EK+ +E + S  +   
Sbjct: 1396 GREKSALESRTSESVDAVVTLRRQLQERDDALAALKDRLEEYGREKSALESRTSESVDAL 1455

Query: 319  -ANMTELTKKIELLEHLNCQIRQTNKE---LENKLATMGTESKAVSSPSKKGSPLISRKS 374
             A   +L ++ + L  L  ++ + ++E   LE++ +       A+    ++    ++  +
Sbjct: 1456 AAMERQLQERDDALAALKDRLEEHSREKSALESRTSESVDALAAMERQLQERDDALAALN 1515

Query: 375  GR-NTASKMKSPWSQLSSETLNQ--DTDKKINKNE--IAKLEMVIQSLNKDLVDKEYVIS 429
             R    S+ KS     +SE+++     ++++ + +  +A L+  ++  +++    E   S
Sbjct: 1516 DRLEEHSREKSALESRTSESVDALAAMERQLQERDDALAALKDRLEEYSREKSALESRTS 1575

Query: 430  EKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQE- 488
            E              +D  +A L+   +++    S +   T+ E V  +A ++ QL++  
Sbjct: 1576 ESVDAVVTLRRQLQERDDALAALKDRLEEYSREKSALESRTS-ESVGALAAMERQLQERD 1634

Query: 489  -----LNDEIKDVN-VKDLIEKL--KSAEEQIT---QLNDEIDAANKNMIKVKSNHKLKL 537
                 LND +++ +  K  +E    +S +  +T   QL +  DA      +++   + K 
Sbjct: 1635 DALAALNDRLEEYDREKSALESRTSESVDAVVTLRRQLQERDDALAALNDRLEEYGREKS 1694

Query: 538  KQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVD-YDSGRMIES 596
                +T  +   ++   +++    + L  L  ++ E   EK  L+    +  D+   +  
Sbjct: 1695 ALESRTSGSVDALAAMERQLQERDDALAALKDRLEEYGREKSALESRTSESVDAVVTLRR 1754

Query: 597  DVYKK---MIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADIS-QLQS 652
             + ++   +  + +  E   +  S LES+  + V  L  ++++  E +D LA +  +L+ 
Sbjct: 1755 QLQERDDALAALNDRLEEYGREKSALESRTSESVDALAAMERQLQERDDALAALKDRLEE 1814

Query: 653  DQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLY------GTIKDLENDKEDI 706
                  +      E +DAL+A +++L    + L   K++L         ++   ++  D 
Sbjct: 1815 HSREKSVLESRTSESVDALAAMERQLQERDDALAALKDRLEEHSREKSALESRTSESVDA 1874

Query: 707  MNKLQNYIQENMD----LTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDL 762
            +  L+  +QE  D    L D+LE+   EK     + +       +     +  ++QERD 
Sbjct: 1875 VVTLRRQLQERDDALAALKDRLEEYGREK-----SALESRTSESVDAVVTLRRQLQERDD 1929

Query: 763  YIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDE 822
             +  ++  L +Y      LE   +   D   ++ER+  +    L   +    EY  ++  
Sbjct: 1930 ALAALKDRLEEYSREKSALESRTSESVDALAAMERQLQERDDALAALKDKLEEYGREKSA 1989

Query: 823  LVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEK 882
            L +R +  +D    + +QL E +     L  + +    E   L+   S+      A+  +
Sbjct: 1990 LESRTSESVDAVVTLRRQLQERDDALAALNDRLEEHSREKSALESRTSESVDALAAMERQ 2049

Query: 883  AN-RTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLE---IEFNTQIES 938
               R D   + + K +   R+ +S L+  T E    +V  ++++++ +      N ++E 
Sbjct: 2050 LQERDDALAALNDKLEEYGRE-KSALESRTSESVDAVVTLRRQLQERDDALAALNDRLEE 2108

Query: 939  AIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNK 983
              R+K  L  +  ++++ +  +E QLQE  + +  L   +EE  +
Sbjct: 2109 HSREKSALESRTSESVDALAAMERQLQERDDALAALKDRLEEYGR 2153



 Score = 63.7 bits (148), Expect = 4e-08
 Identities = 136/730 (18%), Positives = 302/730 (41%), Gaps = 60/730 (8%)

Query: 147  LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQ---IIEAKNKATTXXXXXXXXX 203
            L +   E  +AL+ ++ +++  +  +  L +++ E  +    +E++   +          
Sbjct: 1486 LESRTSESVDALAAMERQLQERDDALAALNDRLEEHSREKSALESRTSESVDALAAMERQ 1545

Query: 204  XXXXXXXXEDTKQQMTKMQENFIAMEA---EWKDEKQRLLKDIESKDVRISSLEEANKLL 260
                       K ++ +      A+E+   E  D    L + ++ +D  +++L++  +L 
Sbjct: 1546 LQERDDALAALKDRLEEYSREKSALESRTSESVDAVVTLRRQLQERDDALAALKD--RLE 1603

Query: 261  EAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLA--KQSIEPSCEEKTEIEEKGSLEI 318
            E +R + +LE S+ ++ +                LA     +E    EK+ +E + S  +
Sbjct: 1604 EYSREKSALE-SRTSESVGALAAMERQLQERDDALAALNDRLEEYDREKSALESRTSESV 1662

Query: 319  ANMTELTKKIE----LLEHLNCQIRQTNKE---LENKLATMGTESKAVSSP-SKKGSPLI 370
              +  L ++++     L  LN ++ +  +E   LE++ +       A+     ++   L 
Sbjct: 1663 DAVVTLRRQLQERDDALAALNDRLEEYGREKSALESRTSGSVDALAAMERQLQERDDALA 1722

Query: 371  SRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNE----IAKLEMVIQSLNKDLVDKEY 426
            + K       + KS     +SE+++     +    E    +A L   ++   ++    E 
Sbjct: 1723 ALKDRLEEYGREKSALESRTSESVDAVVTLRRQLQERDDALAALNDRLEEYGREKSALES 1782

Query: 427  VISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLK 486
              SE              +D  +A L+   ++H    S++   T+ E V+ +A ++ QL+
Sbjct: 1783 RTSESVDALAAMERQLQERDDALAALKDRLEEHSREKSVLESRTS-ESVDALAAMERQLQ 1841

Query: 487  QE------LNDEIKDVN-VKDLIEKL--KSAEEQIT-----QLNDEIDAANKNMIKVKSN 532
            +       L D +++ +  K  +E    +S +  +T     Q  D+  AA K+ ++    
Sbjct: 1842 ERDDALAALKDRLEEHSREKSALESRTSESVDAVVTLRRQLQERDDALAALKDRLEEYGR 1901

Query: 533  HKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVD-YDSG 591
             K  L+   +T ++   V    +++    + L  L  ++ E   EK  L+    +  D+ 
Sbjct: 1902 EKSALES--RTSESVDAVVTLRRQLQERDDALAALKDRLEEYSREKSALESRTSESVDAL 1959

Query: 592  RMIESDVYKK---MIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADIS 648
              +E  + ++   +  +++  E   +  S LES+  + V  +  L+++  E +D LA ++
Sbjct: 1960 AAMERQLQERDDALAALKDKLEEYGREKSALESRTSESVDAVVTLRRQLQERDDALAALN 2019

Query: 649  -QLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKL--DKEQLYGTIKD-LEN--- 701
             +L+              E +DAL+A +++L    + L    DK + YG  K  LE+   
Sbjct: 2020 DRLEEHSREKSALESRTSESVDALAAMERQLQERDDALAALNDKLEEYGREKSALESRTS 2079

Query: 702  DKEDIMNKLQNYIQENMD----LTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKI 757
            +  D +  L+  +QE  D    L D+LE+ S EK     + +       +     ++ ++
Sbjct: 2080 ESVDAVVTLRRQLQERDDALAALNDRLEEHSREK-----SALESRTSESVDALAAMERQL 2134

Query: 758  QERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYT 817
            QERD  +  ++  L +Y      LE   +   D   ++ER+  + G+         +E  
Sbjct: 2135 QERDDALAALKDRLEEYGREKSALESRTSESVDALAAMERQLQERGNAFNIFDGRVNEIC 2194

Query: 818  IQEDELVNRL 827
            +++  L  RL
Sbjct: 2195 MEKSSLGFRL 2204


>UniRef50_Q23Q31 Cluster: Viral A-type inclusion protein repeat
            containing protein; n=1; Tetrahymena thermophila
            SB210|Rep: Viral A-type inclusion protein repeat
            containing protein - Tetrahymena thermophila SB210
          Length = 1823

 Score =  125 bits (301), Expect = 1e-26
 Identities = 221/1176 (18%), Positives = 483/1176 (41%), Gaps = 90/1176 (7%)

Query: 446  DTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKL 505
            DT  ++ QLE   H    SL         +++I + +++L Q L D+I+        +  
Sbjct: 499  DTNTSRYQLEPDVHKT--SLRSSQLQERALHQILEEKDRLIQRLEDKIQRN------DSY 550

Query: 506  KSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSD-----SNKEIVRL 560
             S  E I + N   +     + ++K   + ++   +K   N  K  D      + ++  L
Sbjct: 551  YSKIEHILRNNSNYNEIQTLLNQIKERDQREIDYREKQFQNAIKQKDLLLKQQDGDLQSL 610

Query: 561  TEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLE 620
             + L  L+Q+ +EL+E    LQ      D    + S+   + IE E L + R K    ++
Sbjct: 611  RDNLFILNQQNSELKERLRILQTQ----DIQSQLLSNKQIQNIE-EALDKQRFKYEEKIQ 665

Query: 621  SQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELAL 680
            + + ++     I+  +  + +  L     LQ+D+   +      EE       +K E  +
Sbjct: 666  NYRSEIESLKGIINAEKKKNQQILLQTELLQNDK---DYIQQQFEESEQRYYQAKNEAEM 722

Query: 681  VIENLKLDK----EQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAE---KIS 733
            ++E L   K          I+ LEN+ E +     N   E   L  + +K + +   K +
Sbjct: 723  LLEKLHQAKLANATNERNRIQSLENEIEQLRQNQLNIYSEEGKLIQQYKKQNEDLTKKYN 782

Query: 734  ELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRY 793
             L   +   E+ K++          +++L  E IE E  + K     L+  +  +E  RY
Sbjct: 783  HLQKLLEENEKQKLE-DLKKQQDAHQKELQ-EKIEKEKLEQKEPEQNLQPVVQDIESNRY 840

Query: 794  SLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQK 853
             ++ +A +     Q+ +   +E     +EL       +D+++ +     +I+H N +LQ+
Sbjct: 841  KMKYEAKK-----QKYKNLKTEMKNMYEELKQMTQENIDNNQKINSLNQQIQHYNHQLQQ 895

Query: 854  KNQILLEENQNLQISLSDMQQHYNALVEKANRT--DLAESESTKYQTQLR---DLESNLK 908
             NQ L      LQ S  D      A++EK      D  +    KYQ +L+   D   NLK
Sbjct: 896  ANQQL----HLLQSSNKDNVNSRIAMIEKIKDRFEDQLKQSQQKYQEELQLQADQIQNLK 951

Query: 909  -------RITHEHQTLIVQKKKEIEDLEIEFNTQIESA------IRDKKVLNEKYEKNIE 955
                   R   + Q  I +K ++I  L+++   Q E        ++ K+ L++K +   +
Sbjct: 952  AEIERKMRDLQKLQNTIQEKDEDINSLKVQIQEQKEKQKKSSKNLQPKEDLSQKVKSLNQ 1011

Query: 956  YVTQLEAQLQEYKNNIENLNMN---VEELNKMNLELIDKHVQKQQTQSPDYTEQYINEIN 1012
             ++Q E++++E +  ++++      +E+  K   +  +K +Q+ +TQ   + +Q  NE +
Sbjct: 1012 ALSQKESKIEELQKELKDIKSEKDEIEKTTKKKQQNFEKKIQEIETQKKQFEDQIFNESD 1071

Query: 1013 KLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLL 1072
            K   L +   +++   N+++      Y   + +Y+   +QF  K    + E+  + +++ 
Sbjct: 1072 KSTILFESTLKQLRIENKELER---KYFEEIENYKIIQSQFCEKEMLYKNEIDDLQRKIQ 1128

Query: 1073 DSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMI--ISSTIEPMSDDANNVDX 1130
            + K H     I  ++    +++L+E  +     I      +  +S +   +    N +  
Sbjct: 1129 ELKHHVTYDNINQQKVSRNVQQLQEEVILAREQIRDLSLQLKDVSESAFQLERQLNEIIQ 1188

Query: 1131 XXXXXXXXXXXLK-VQEEEEFIQERSVLQEQ-SAKLNTELQECYTKIIQLETLNTELTGH 1188
                        K +++E E ++ RS  ++Q   ++N EL+     + +++     ++  
Sbjct: 1189 KYEESQQQIIKYKAIEDEMEQLKRRSQREQQYKEQINEELEALKQYVQEIQRQKDNISVQ 1248

Query: 1189 DVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREA 1248
              +  E I + K   + L      L     EL +  +        +++  + Q +     
Sbjct: 1249 IKLKDEAIQEGKEYQQDLIKFMKELEQKYQELENQTTGQSYDLNSQVS-YYIQQVDLLTF 1307

Query: 1249 DFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRN 1308
            + ++   + +   S   ++ ++  D      QEE  K  T+E   S  +K   K++ L+ 
Sbjct: 1308 ENKRIHDKNQTINSDLAAQIKESKDLKARLIQEE-QKSKTLEAQLSQYDK--TKKKQLQT 1364

Query: 1309 LQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTE----NQSYKQMQE 1364
            L+ ++A+  +  EIL  E E  ++                   +       NQ YK+  E
Sbjct: 1365 LKSQFAEQKDYNEILYQEKEALQIKIEEMHQIMIDSEQIYQTHINIVKSKFNQDYKEFIE 1424

Query: 1365 QSILNI-----NEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQK 1419
            Q    I      ++   +K                V++ EAK+  ++++++L   ++ +K
Sbjct: 1425 QVNAKIKFFIAKKDQVDVKSKVLKMFERYLEEIPTVSEKEAKIKSMSNKIQLLKDQLAEK 1484

Query: 1420 THEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHEN--ANHYETMQ 1477
             +E  I   Q    +   +   V       +   +  ++  +  +  H        +  +
Sbjct: 1485 QNE--IENQQNKGNYNPNQTNNVNNANNAVNKAVKPSNKYTLETIVEHAKIIVQKQDIEK 1542

Query: 1478 KESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLN 1537
              +EI++ K + E   K +E  SLNKQ  E ++ ++++ A   + +  L+N++     + 
Sbjct: 1543 LFTEIQQYKQLVE--QKQSEIDSLNKQGHEKDEKIKQQSAFIQKSKEDLQNEKQRADKIQ 1600

Query: 1538 DEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLD 1573
            +E   +Q  +++    +Q  +   ++T + ++E+L+
Sbjct: 1601 EEKDEIQKQIKS----LQAQLKAKNNTIEQKNEELN 1632



 Score =  107 bits (258), Expect = 2e-21
 Identities = 166/835 (19%), Positives = 371/835 (44%), Gaps = 71/835 (8%)

Query: 299  SIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKA 358
            S++   +E+ E ++K S  +    +L++K++ L     Q     +EL+ +L  + +E   
Sbjct: 977  SLKVQIQEQKEKQKKSSKNLQPKEDLSQKVKSLNQALSQKESKIEELQKELKDIKSEKDE 1036

Query: 359  VSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLN 418
            +   +KK      +K       ++++   Q   +  N ++DK     E    ++ I+  N
Sbjct: 1037 IEKTTKKKQQNFEKK-----IQEIETQKKQFEDQIFN-ESDKSTILFESTLKQLRIE--N 1088

Query: 419  KDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEI 478
            K+L  K +    ++            +  ++ + +++  Q        HV  +  +  ++
Sbjct: 1089 KELERKYF----EEIENYKIIQSQFCEKEMLYKNEIDDLQRKIQELKHHVTYDNINQQKV 1144

Query: 479  AKVQEQLKQEL---NDEIKDVN--VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNH 533
            ++  +QL++E+    ++I+D++  +KD+ E     E Q+ ++  + + + + +IK K+  
Sbjct: 1145 SRNVQQLQEEVILAREQIRDLSLQLKDVSESAFQLERQLNEIIQKYEESQQQIIKYKAIE 1204

Query: 534  KLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNL--QLHLVD--YD 589
              +++Q+++     S+     KE  ++ EEL  L Q V E++ +K N+  Q+ L D    
Sbjct: 1205 D-EMEQLKRR----SQREQQYKE--QINEELEALKQYVQEIQRQKDNISVQIKLKDEAIQ 1257

Query: 590  SGRMIESDVYKKMIEMENL---AETRLKAISL-LESQKFDLVQELHILQQKYDEVEDK-- 643
             G+  + D+ K M E+E      E +    S  L SQ    +Q++ +L  +   + DK  
Sbjct: 1258 EGKEYQQDLIKFMKELEQKYQELENQTTGQSYDLNSQVSYYIQQVDLLTFENKRIHDKNQ 1317

Query: 644  ---------LADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYG 694
                     + +   L++  +  E KS  LE Q+     +KK+    +++ +  +++ Y 
Sbjct: 1318 TINSDLAAQIKESKDLKARLIQEEQKSKTLEAQLSQYDKTKKKQLQTLKS-QFAEQKDYN 1376

Query: 695  TIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKI-QTQFGI 753
             I  L  +KE +  K++   Q  +D     E++    I+ + +K N + +  I Q    I
Sbjct: 1377 EI--LYQEKEALQIKIEEMHQIMID----SEQIYQTHINIVKSKFNQDYKEFIEQVNAKI 1430

Query: 754  DAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAY 813
               I ++D    +++S++ K   R      +++  E +  S+  K   L   L EKQ   
Sbjct: 1431 KFFIAKKDQV--DVKSKVLKMFERYLEEIPTVSEKEAKIKSMSNKIQLLKDQLAEKQNEI 1488

Query: 814  SEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQ 873
                 + +   N+   + + +  V K +        E   ++  ++ + Q+++   +++Q
Sbjct: 1489 ENQQNKGNYNPNQTNNVNNANNAVNKAVKPSNKYTLETIVEHAKIIVQKQDIEKLFTEIQ 1548

Query: 874  QHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFN 933
            Q+   + +K +  D    +  +   +++   + +++   + Q    Q+  +I++ + E  
Sbjct: 1549 QYKQLVEQKQSEIDSLNKQGHEKDEKIKQQSAFIQKSKEDLQN-EKQRADKIQEEKDEIQ 1607

Query: 934  TQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHV 993
             QI+S     K  N   E+  E + ++ A L++Y + ++  N   EE    N +LI    
Sbjct: 1608 KQIKSLQAQLKAKNNTIEQKNEELNKI-AFLKQYNDQLKEDNAKKEEQIAQNEKLIKNQR 1666

Query: 994  QK-----QQTQSPDYTEQYINEI-NKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYE 1047
             +     +Q Q  +  + Y+ E+  K N   K K+E I+ LN      Q    S+ +D  
Sbjct: 1667 DQIGKLTKQIQEIERKDDYVKEMQEKYN---KMKEEAILVLNDN-KKYQEQIASLKNDIV 1722

Query: 1048 SK--LAQFTTKLENMEEEMQRVSKQLLDSKQHNEE----LQILVREQDDQIKELK 1096
             K  L Q   +LE    ++++V ++L ++   N++    L   ++ +D   ++LK
Sbjct: 1723 RKDLLLQDKIQLEEKHIKLKQVYEKLKENNSKNKDNIKKLTATIKMKDQVNQQLK 1777



 Score = 91.1 bits (216), Expect = 2e-16
 Identities = 189/1030 (18%), Positives = 442/1030 (42%), Gaps = 108/1030 (10%)

Query: 309  EIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSP 368
            E+++     I N  ++    + ++H N Q++Q N++L        +    V+S       
Sbjct: 864  ELKQMTQENIDNNQKINSLNQQIQHYNHQLQQANQQLH---LLQSSNKDNVNSRIAMIEK 920

Query: 369  LISRKSGRNTASKMK-SPWSQLSSETL-NQDTDKKINKNEIAKLEMVIQSLNKDLVDKEY 426
            +  R   +   S+ K     QL ++ + N   + +    ++ KL+  IQ  ++D+   + 
Sbjct: 921  IKDRFEDQLKQSQQKYQEELQLQADQIQNLKAEIERKMRDLQKLQNTIQEKDEDINSLKV 980

Query: 427  VISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLI-HVGTNTEDV----NEIAKV 481
             I E+             K+ L  +++  +Q   +  S I  +    +D+    +EI K 
Sbjct: 981  QIQEQKEKQKKSSKNLQPKEDLSQKVKSLNQALSQKESKIEELQKELKDIKSEKDEIEKT 1040

Query: 482  QEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVK--SNHKLKLKQ 539
             ++ +Q    +I+++  +      K  E+QI   +D+     ++ +K     N +L+ K 
Sbjct: 1041 TKKKQQNFEKKIQEIETQK-----KQFEDQIFNESDKSTILFESTLKQLRIENKELERKY 1095

Query: 540  MQKTIDNFSKVSDS--NKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESD 597
             ++ I+N+  +      KE++    E+  L +K+ EL+        H V YD+  + +  
Sbjct: 1096 FEE-IENYKIIQSQFCEKEML-YKNEIDDLQRKIQELK--------HHVTYDN--INQQK 1143

Query: 598  VYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCS 657
            V + + +++       + + L   Q  DL  +L  + +   ++E +L +I Q   +    
Sbjct: 1144 VSRNVQQLQ-------EEVILAREQIRDLSLQLKDVSESAFQLERQLNEIIQKYEESQQQ 1196

Query: 658  EIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQ---NYI 714
             IK   +E++++ L    +      E +  + E L   +++++  K++I  +++     I
Sbjct: 1197 IIKYKAIEDEMEQLKRRSQREQQYKEQINEELEALKQYVQEIQRQKDNISVQIKLKDEAI 1256

Query: 715  QENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKY 774
            QE  +    L K     + EL  K    E       + +++++     YI+ ++  L+  
Sbjct: 1257 QEGKEYQQDLIKF----MKELEQKYQELENQTTGQSYDLNSQV---SYYIQQVDL-LTFE 1308

Query: 775  KSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHD 834
              RI   +++  +  D    ++   D     +QE+QK+    T++        A L  +D
Sbjct: 1309 NKRI--HDKNQTINSDLAAQIKESKDLKARLIQEEQKS---KTLE--------AQLSQYD 1355

Query: 835  RVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESEST 894
            +  +KQL  ++ +  E +  N+IL +E + LQI + +M Q             + +SE  
Sbjct: 1356 KTKKKQLQTLKSQFAEQKDYNEILYQEKEALQIKIEEMHQ------------IMIDSEQI 1403

Query: 895  KYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNI 954
             YQT +  ++S   +   +++  I Q   +I+   I    Q++   +  K+  E+Y + I
Sbjct: 1404 -YQTHINIVKS---KFNQDYKEFIEQVNAKIK-FFIAKKDQVDVKSKVLKMF-ERYLEEI 1457

Query: 955  EYVTQLEAQLQEYKNNIENL-NMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEI-- 1011
              V++ EA+++   N I+ L +   E+ N++  +    +    QT + +     +N+   
Sbjct: 1458 PTVSEKEAKIKSMSNKIQLLKDQLAEKQNEIENQQNKGNYNPNQTNNVNNANNAVNKAVK 1517

Query: 1012 --NKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSK 1069
              NK       +  +II   Q I              E K ++  +  +   E+ +++ +
Sbjct: 1518 PSNKYTLETIVEHAKIIVQKQDIEKLFTEIQQYKQLVEQKQSEIDSLNKQGHEKDEKIKQ 1577

Query: 1070 QLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVD 1129
            Q    ++  E+LQ   +++ D+I+E K+ ++  ++   + +    ++TIE  +++ N + 
Sbjct: 1578 QSAFIQKSKEDLQ-NEKQRADKIQEEKD-EIQKQIKSLQAQLKAKNNTIEQKNEELNKIA 1635

Query: 1130 XXXXXXXXXXXXLKVQEEEEFIQERSVL---QEQSAKLNTELQECYTKIIQLETLNTELT 1186
                           ++EE+  Q   ++   ++Q  KL  ++QE   K   ++ +  +  
Sbjct: 1636 FLKQYNDQLKED-NAKKEEQIAQNEKLIKNQRDQIGKLTKQIQEIERKDDYVKEMQEKYN 1694

Query: 1187 GHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELW---KQHL 1243
                     +N  K   EQ+ +  ++++     L+  I   ++++  ++ +++   K++ 
Sbjct: 1695 KMKEEAILVLNDNKKYQEQIASLKNDIVRKDLLLQDKIQ--LEEKHIKLKQVYEKLKENN 1752

Query: 1244 AQREADFQKTEHELRVQLSAFESKYEQLLDS---VQSSTQEETNKIVTMEQ--------- 1291
            ++ + + +K    ++++    +    Q+ D     Q  ++ +TN ++  E          
Sbjct: 1753 SKNKDNIKKLTATIKMKDQVNQQLKSQVFDDEDISQDQSENKTNNVIKQENWKKSPVRFT 1812

Query: 1292 VTSLQNKLQD 1301
             T+ QN+LQD
Sbjct: 1813 KTTSQNQLQD 1822



 Score = 89.8 bits (213), Expect = 5e-16
 Identities = 179/928 (19%), Positives = 390/928 (42%), Gaps = 82/928 (8%)

Query: 629  ELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLD 688
            E+   Q  +D+ ED    I ++       E+K +H+E ++       K++ L  +   L 
Sbjct: 392  EIEPFQIIFDQYEDNEKRIEKMYIKNSDPELKDMHVEFKL----FDTKKIRLSPQCFVLA 447

Query: 689  KEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQ 748
              ++   I  +E    +I ++L+  +Q+ M +T        E    +  +INH+   +  
Sbjct: 448  PNEIKEVI--IELIPCEITSRLE--LQDFMFVTAN----QGEFEKRISIQINHKSLQRFD 499

Query: 749  TQFGIDAKIQERDLYIENIESELSKYKSRICRLEESI--AVMEDRRYSLERKADQLGSYL 806
            T     ++ Q        +E ++ K   R  +L+E     ++E++   ++R  D+    +
Sbjct: 500  TN---TSRYQ--------LEPDVHKTSLRSSQLQERALHQILEEKDRLIQRLEDK----I 544

Query: 807  QEKQKAYS--EYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQ---KKNQILLEE 861
            Q     YS  E+ ++ +   N +  L+  +++ E+   EI++  K+ Q   K+  +LL++
Sbjct: 545  QRNDSYYSKIEHILRNNSNYNEIQTLL--NQIKERDQREIDYREKQFQNAIKQKDLLLKQ 602

Query: 862  NQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNL---KRITHEHQTLI 918
                  SL D     N  +     ++L E      QTQ  D++S L   K+I +  + L 
Sbjct: 603  QDGDLQSLRD-----NLFILNQQNSELKE-RLRILQTQ--DIQSQLLSNKQIQNIEEALD 654

Query: 919  VQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNV 978
             Q+ K  E ++  + ++IES    K ++N + +KN + + Q E  LQ  K+ I+      
Sbjct: 655  KQRFKYEEKIQ-NYRSEIESL---KGIINAEKKKNQQILLQTEL-LQNDKDYIQ---QQF 706

Query: 979  EELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVS 1038
            EE  +   +  ++     +           NE N++ +L    + EI  L Q   N    
Sbjct: 707  EESEQRYYQAKNEAEMLLEKLHQAKLANATNERNRIQSL----ENEIEQLRQNQLNIYSE 762

Query: 1039 YMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLL-DSKQHNEELQILVREQDDQIK-ELK 1096
               ++  Y+ +    T K  ++++ ++   KQ L D K+  +  Q  ++E+ ++ K E K
Sbjct: 763  EGKLIQQYKKQNEDLTKKYNHLQKLLEENEKQKLEDLKKQQDAHQKELQEKIEKEKLEQK 822

Query: 1097 ETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSV 1156
            E +   +  +   E        E       N+             +  QE  +  Q+ + 
Sbjct: 823  EPEQNLQPVVQDIESNRYKMKYEAKKQKYKNLKTEMKNMYEELKQM-TQENIDNNQKINS 881

Query: 1157 LQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQI-NQLKSKLEQLNTENDNLLS 1215
            L +Q    N +LQ+   ++  L++ N +     +   E+I ++ + +L+Q   +    L 
Sbjct: 882  LNQQIQHYNHQLQQANQQLHLLQSSNKDNVNSRIAMIEKIKDRFEDQLKQSQQKYQEELQ 941

Query: 1216 TVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSV 1275
              A+   ++ + ++++  ++ +L +  + +++ D     + L+VQ+   E K +Q   S 
Sbjct: 942  LQADQIQNLKAEIERKMRDLQKL-QNTIQEKDEDI----NSLKVQIQ--EQKEKQKKSSK 994

Query: 1276 QSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFX 1335
                +E+ +     ++V SL   L  KE  +  LQ++  D+ ++ + +    + ++  F 
Sbjct: 995  NLQPKEDLS-----QKVKSLNQALSQKESKIEELQKELKDIKSEKDEIEKTTKKKQQNFE 1049

Query: 1336 XXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRV 1395
                            +  E+     + E ++  +  EN +L++              + 
Sbjct: 1050 KKIQEIETQKKQFEDQIFNESDKSTILFESTLKQLRIENKELERKYFEEIENYKIIQSQF 1109

Query: 1396 NDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEK 1455
             + E         L+ K  E+        I   + +   + ++++++   ++I DL+ + 
Sbjct: 1110 CEKEMLYKNEIDDLQRKIQELKHHVTYDNINQQKVSRNVQQLQEEVILAREQIRDLSLQL 1169

Query: 1456 E--SELAI-LRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAE-LNKA 1511
            +  SE A  L  +++E    YE  + + +I + K IE+   ++       +Q  E +N+ 
Sbjct: 1170 KDVSESAFQLERQLNEIIQKYE--ESQQQIIKYKAIEDEMEQLKRRSQREQQYKEQINEE 1227

Query: 1512 LEEEVAKTNEMQTALENQEIEIVTLNDE 1539
            LE       E+Q   +N  ++I  L DE
Sbjct: 1228 LEALKQYVQEIQRQKDNISVQI-KLKDE 1254



 Score = 76.6 bits (180), Expect = 5e-12
 Identities = 161/898 (17%), Positives = 389/898 (43%), Gaps = 68/898 (7%)

Query: 140  QLGDVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKD---QIIEAKNKATT-- 194
            ++ D+  L NTI+EKD  ++ L+V+++  +       + +  K+   Q +++ N+A +  
Sbjct: 957  KMRDLQKLQNTIQEKDEDINSLKVQIQEQKEKQKKSSKNLQPKEDLSQKVKSLNQALSQK 1016

Query: 195  -XXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSL 253
                              ++ ++   K Q+NF     E + +K++    I ++  + + L
Sbjct: 1017 ESKIEELQKELKDIKSEKDEIEKTTKKKQQNFEKKIQEIETQKKQFEDQIFNESDKSTIL 1076

Query: 254  EEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEK 313
             E+   L+  R E      K  +E+E               L K  I+    +  E++  
Sbjct: 1077 FEST--LKQLRIENKELERKYFEEIEN-YKIIQSQFCEKEMLYKNEIDDLQRKIQELKHH 1133

Query: 314  GSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISR- 372
             + +  N  ++++ ++ L+      R+  ++L  +L  +   S++     ++ + +I + 
Sbjct: 1134 VTYDNINQQKVSRNVQQLQEEVILAREQIRDLSLQLKDV---SESAFQLERQLNEIIQKY 1190

Query: 373  KSGRNTASKMKS---PWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVIS 429
            +  +    K K+      QL   +  +   K+    E+  L+  +Q + +   +    I 
Sbjct: 1191 EESQQQIIKYKAIEDEMEQLKRRSQREQQYKEQINEELEALKQYVQEIQRQKDNISVQIK 1250

Query: 430  EKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQL--KQ 487
             KD                + +L+ ++Q+     +      N++    I +V       +
Sbjct: 1251 LKDEAIQEGKEYQQDLIKFMKELEQKYQELENQTTGQSYDLNSQVSYYIQQVDLLTFENK 1310

Query: 488  ELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNF 547
             ++D+ + +N  DL  ++K +++   +L  E   +     ++    K K KQ+Q     F
Sbjct: 1311 RIHDKNQTIN-SDLAAQIKESKDLKARLIQEEQKSKTLEAQLSQYDKTKKKQLQTLKSQF 1369

Query: 548  SKVSDSN------KEIVRL-TEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIE--SDV 598
            ++  D N      KE +++  EE+H +     ++ +   N+     + D    IE  +  
Sbjct: 1370 AEQKDYNEILYQEKEALQIKIEEMHQIMIDSEQIYQTHINIVKSKFNQDYKEFIEQVNAK 1429

Query: 599  YKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSE 658
             K  I  ++  + + K + + E      ++E+  + +K  +++  +++  QL  DQ+  +
Sbjct: 1430 IKFFIAKKDQVDVKSKVLKMFER----YLEEIPTVSEKEAKIK-SMSNKIQLLKDQLAEK 1484

Query: 659  IKSVHLEEQIDALSASKKELALVIENL--KLDKEQLYGTIKDLENDKEDIMNKLQNYIQE 716
               +  ++     + ++        N   K  K     T++ +    + I+ K    I++
Sbjct: 1485 QNEIENQQNKGNYNPNQTNNVNNANNAVNKAVKPSNKYTLETIVEHAKIIVQKQD--IEK 1542

Query: 717  NMDLTDKLEKMSAEKISEL--LAKINHEEQSKIQTQFGIDAKIQERDLYIENIESE-LSK 773
                  + +++  +K SE+  L K  HE+  KI+ Q     K +E DL  E   ++ + +
Sbjct: 1543 LFTEIQQYKQLVEQKQSEIDSLNKQGHEKDEKIKQQSAFIQKSKE-DLQNEKQRADKIQE 1601

Query: 774  YKSRICRLEESI-AVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMD 832
             K  I +  +S+ A ++ +  ++E+K ++L      KQ  Y++  ++ED    +   +  
Sbjct: 1602 EKDEIQKQIKSLQAQLKAKNNTIEQKNEELNKIAFLKQ--YND-QLKEDN-AKKEEQIAQ 1657

Query: 833  HDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESE 892
            ++++++ Q  +I    K++Q+     +E   +    + +MQ+ YN + E+A    L  ++
Sbjct: 1658 NEKLIKNQRDQIGKLTKQIQE-----IERKDDY---VKEMQEKYNKMKEEA---ILVLND 1706

Query: 893  STKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEK 952
            + KYQ Q+  L++++ R     + L++Q K ++E+  I+   Q+   +++    N+   K
Sbjct: 1707 NKKYQEQIASLKNDIVR-----KDLLLQDKIQLEEKHIKLK-QVYEKLKENNSKNKDNIK 1760

Query: 953  NIEYVTQLEAQL-QEYKNNI---ENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQ 1006
             +    +++ Q+ Q+ K+ +   E+++ +  E NK N  +  ++ +K   +    T Q
Sbjct: 1761 KLTATIKMKDQVNQQLKSQVFDDEDISQDQSE-NKTNNVIKQENWKKSPVRFTKTTSQ 1817



 Score = 58.8 bits (136), Expect = 1e-06
 Identities = 131/711 (18%), Positives = 283/711 (39%), Gaps = 76/711 (10%)

Query: 890  ESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKK---VL 946
            + E   +Q      E N KRI    +  I     E++D+ +EF       IR      VL
Sbjct: 390  DMEIEPFQIIFDQYEDNEKRI---EKMYIKNSDPELKDMHVEFKLFDTKKIRLSPQCFVL 446

Query: 947  --NEKYEKNIEYVT---QLEAQLQEYK----NNIENLNMNVEELNKMNLELIDKHVQKQQ 997
              NE  E  IE +        +LQ++     N  E       ++N  +L+  D +  + Q
Sbjct: 447  APNEIKEVIIELIPCEITSRLELQDFMFVTANQGEFEKRISIQINHKSLQRFDTNTSRYQ 506

Query: 998  TQSPDYTEQYIN----EINKLNALLKQKDEEIIALNQKI--NNAQVSYMSMVSDYESKLA 1051
             + PD  +  +     +   L+ +L++KD  I  L  KI  N++  S +  +    S   
Sbjct: 507  LE-PDVHKTSLRSSQLQERALHQILEEKDRLIQRLEDKIQRNDSYYSKIEHILRNNSNYN 565

Query: 1052 QFTTKLENMEEEMQR-VSKQLLDSKQHNEELQILVREQDDQIKELKETKLTF-EMNIPKT 1109
            +  T L  ++E  QR +  +    +   ++  +L+++QD  ++ L++      + N    
Sbjct: 566  EIQTLLNQIKERDQREIDYREKQFQNAIKQKDLLLKQQDGDLQSLRDNLFILNQQNSELK 625

Query: 1110 EGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQ 1169
            E + I  T +  S   +N               K   EE+    RS ++     +N E +
Sbjct: 626  ERLRILQTQDIQSQLLSNKQIQNIEEALDKQRFKY--EEKIQNYRSEIESLKGIINAEKK 683

Query: 1170 ECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVD 1229
            +    ++Q E L  +    D + Q+Q  + + +  Q   E + LL  + + +  +++A +
Sbjct: 684  KNQQILLQTELLQND---KDYI-QQQFEESEQRYYQAKNEAEMLLEKLHQAK--LANATN 737

Query: 1230 QRG-FEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVT 1288
            +R   +  E   + L Q + +    E +L   +  ++ + E L     +       K++ 
Sbjct: 738  ERNRIQSLENEIEQLRQNQLNIYSEEGKL---IQQYKKQNEDL-----TKKYNHLQKLLE 789

Query: 1289 MEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXX 1348
              +   L++  + ++ H + LQEK         I + ++E ++                 
Sbjct: 790  ENEKQKLEDLKKQQDAHQKELQEK---------IEKEKLEQKEPEQNLQPVVQDIESNRY 840

Query: 1349 XXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQ 1408
                  + Q YK ++ + + N+ EE  Q+ + +            ++N    ++    HQ
Sbjct: 841  KMKYEAKKQKYKNLKTE-MKNMYEELKQMTQENIDNNQ-------KINSLNQQIQHYNHQ 892

Query: 1409 LELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHE 1468
            L+  + +++         +  R    E ++ +  +  K+ +   Y++E +L         
Sbjct: 893  LQQANQQLHLLQSSNKDNVNSRIAMIEKIKDRFEDQLKQSQQ-KYQEELQL--------- 942

Query: 1469 NANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALEN 1528
             A+  + ++ E E  +++ +++L   I E    ++ +  L   ++E+  K  +    L+ 
Sbjct: 943  QADQIQNLKAEIE-RKMRDLQKLQNTIQEK---DEDINSLKVQIQEQKEKQKKSSKNLQP 998

Query: 1529 QEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKE 1579
            +E     L+ ++ +L   +    SKI++      D K  +DE    T  K+
Sbjct: 999  KE----DLSQKVKSLNQALSQKESKIEELQKELKDIKSEKDEIEKTTKKKQ 1045


>UniRef50_P49454 Cluster: Centromere protein F; n=15; Eutheria|Rep:
            Centromere protein F - Homo sapiens (Human)
          Length = 3210

 Score =  125 bits (301), Expect = 1e-26
 Identities = 273/1350 (20%), Positives = 579/1350 (42%), Gaps = 118/1350 (8%)

Query: 244  ESKDVRISSLEEANKLLEAARFEISLEHSKLAQELE-QXXXXXXXXXXXXXXLAKQSIEP 302
            E+       +EE   L E  R   SLE  KL +++E Q              L+ +  E 
Sbjct: 1636 ETPSAPAKGVEELESLCEVYRQ--SLE--KLEEKMESQGIMKNKEIQELEQLLSSERQEL 1691

Query: 303  SCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNK-ELENKLATMGTESKAVSS 361
             C  K  + E    +   +T +T  +E+   L  + +QT +  LE ++A +  +   +SS
Sbjct: 1692 DCLRKQYLSENEQWQ-QKLTSVT--LEMESKLAAEKKQTEQLSLELEVARLQLQGLDLSS 1748

Query: 362  PSKKGSPLISRKSGRNTASKM-KSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKD 420
             S  G        GRN +  + K   S+ +  T   D  +  +K+    L + I+ + + 
Sbjct: 1749 RSLLGIDTEDAIQGRNESCDISKEHTSETTERTPKHDVHQICDKDAQQDLNLDIEKITET 1808

Query: 421  LVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAK 480
               K       +           G+D      +   +    GP+ +       +  +I  
Sbjct: 1809 GAVKPTGECSGEQSPDTNYEPP-GEDKTQGSSECISELSFSGPNALVPMDFLGNQEDIHN 1867

Query: 481  VQEQLKQELNDEIKDVNV-KDLIEKLKSAEEQITQLNDEIDAANKN-MIKVKSNHKLKLK 538
            +Q ++K+  N+ ++ ++V +D   K++S   ++ +L+ ++       M K+++       
Sbjct: 1868 LQLRVKETSNENLRLLHVIEDRDRKVESLLNEMKELDSKLHLQEVQLMTKIEA-----CI 1922

Query: 539  QMQKTIDNFSKV-SDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESD 597
            +++K +    K  SD ++++   + +   L Q+V   E    +L++H  D  S   I  +
Sbjct: 1923 ELEKIVGELKKENSDLSEKLEYFSCDHQELLQRVETSEGLNSDLEMH-ADKSSREDIGDN 1981

Query: 598  VYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVE-DKLADISQLQSDQVC 656
            V K     +         +S + S+K  +  E   L+   + V+ +KL     L+ D   
Sbjct: 1982 VAKVNDSWKERFLDVENELSRIRSEKASIEHEALYLEADLEVVQTEKLC----LEKDNEN 2037

Query: 657  SEIKSVHLEEQIDALSASKKELALVIENLK-----LDK--EQLYGTIKDLENDKEDIMNK 709
             +   V LEE++  +++ + +L   ++ +      LD+  E++    ++LE+ + + ++ 
Sbjct: 2038 KQKVIVCLEEELSVVTSERNQLRGELDTMSKKTTALDQLSEKMKEKTQELESHQSECLHC 2097

Query: 710  LQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIES 769
            +Q    E  + T+ L+ +S++ +SELL    H  Q K+Q+       +      +EN  +
Sbjct: 2098 IQVAEAEVKEKTELLQTLSSD-VSELLKDKTHL-QEKLQSLEKDSQALSLTKCELENQIA 2155

Query: 770  ELSKYKSRICRLEESI-AVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDEL----- 823
            +L+K K  + +  ES+ A + +  Y     +  L + L EK +     +  ++E+     
Sbjct: 2156 QLNKEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRR 2215

Query: 824  -VNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEK 882
             + +L V ++ D   EK+ L I  + KE +++N  L ++ +NL+  L   +++   ++  
Sbjct: 2216 GIEKLRVRIEAD---EKKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQELVILD 2272

Query: 883  ANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRD 942
            A  +  AE E+ K  TQ+ ++  +LK    +  TL  +K+   + ++ E   Q+     D
Sbjct: 2273 AENSK-AEVETLK--TQIEEMARSLKVFELDLVTLRSEKENLTKQIQ-EKQGQLSEL--D 2326

Query: 943  KKVLNEKYEKNIEYVTQLEAQL-QEYKNNIENLNMNVEELNKMNLELI-DKHVQKQQTQS 1000
            K  L   ++  +E   Q E Q+ +E K  +E L   ++ELN+    L  D+ + K   QS
Sbjct: 2327 K--LLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQS 2384

Query: 1001 PD----YTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTK 1056
             D       Q  N I KL A L+  +++ + + Q++           S++ + L +   +
Sbjct: 2385 LDPPIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKE---------SEHHADLLK--GR 2433

Query: 1057 LENMEEEMQ--RVSKQ--LLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGM 1112
            +EN+E E++  R +++   L+++    E++ L  + +   + L+  +L  ++   ++E  
Sbjct: 2434 VENLERELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGLEL--DVVTIRSEKE 2491

Query: 1113 IISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECY 1172
             +++ ++   +  + ++            +  ++E+E +Q +         L T+L+E  
Sbjct: 2492 NLTNELQKEQERISELEIINSSFEN----ILQEKEQEKVQMKEKSSTAMEMLQTQLKELN 2547

Query: 1173 TKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRG 1232
             ++  L          +     Q+  L+ +  QL    D   +    L+SS++  + +  
Sbjct: 2548 ERVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQE-- 2605

Query: 1233 FEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQV 1292
                E  KQ L +++ +  + +++++ Q        EQL+  +   +Q E    +  EQ 
Sbjct: 2606 ---VEDGKQKLEKKDEEISRLKNQIQDQ--------EQLVSKL---SQVEGEHQLWKEQN 2651

Query: 1293 TSLQNKLQDKEEHLRNLQEKYADVINQIEILRS---EIEDE-------KVAFXXXXXXXX 1342
              L+N   + E+ ++ LQ K A + + +E+L+S    +E+E       K++F        
Sbjct: 2652 LELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEKVNKMT 2711

Query: 1343 XXXXXXXXDLRTENQSYKQMQEQSILNINE--ENAQLKKSSXXXXXXXXXXXXRVNDAEA 1400
                    ++    Q   ++QE+     N      QL                  N    
Sbjct: 2712 AKETELQREMHEMAQKTAELQEELSGEKNRLAGELQLLLEEIKSSKDQLKELTLENSELK 2771

Query: 1401 KVLELTHQLEL-KDSEIYQKTHEYTITLTQRNDEFENV-----RQQLVEYEKRIEDLTYE 1454
            K L+  H+ ++ K+ ++ ++  EY + L +   + + +     +Q  VE +   E LT  
Sbjct: 2772 KSLDCMHKDQVEKEGKVREEIAEYQLRLHEAEKKHQALLLDTNKQYEVEIQTYREKLT-S 2830

Query: 1455 KESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEE 1514
            KE  L+  +L++    +  E +    +    +++EEL  K T+  +L K V +L K  E 
Sbjct: 2831 KEECLSSQKLEIDLLKSSKEELNNSLK-ATTQILEEL--KKTKMDNL-KYVNQLKKENER 2886

Query: 1515 EVAKTNEMQTALENQEIEIVTLNDEITNLQ 1544
               K   +  + +  E E   L  E++ LQ
Sbjct: 2887 AQGKMKLLIKSCKQLEEEKEILQKELSQLQ 2916



 Score =  119 bits (287), Expect = 6e-25
 Identities = 207/951 (21%), Positives = 423/951 (44%), Gaps = 82/951 (8%)

Query: 235  EKQRLLKDIESKDVRISSLEEANKLLEAARFEISLE---HSKLAQELEQXXXXXXXXXXX 291
            EK  L KD E+K   I  LEE   ++ + R ++  E    SK    L+Q           
Sbjct: 2027 EKLCLEKDNENKQKVIVCLEEELSVVTSERNQLRGELDTMSKKTTALDQLSEKMKEKTQE 2086

Query: 292  XXXLAKQSI------EPSCEEKTEIEEKGSLEIANM----TELTKKIELLEHLNCQIRQT 341
                  + +      E   +EKTE+ +  S +++ +    T L +K++ LE  +  +  T
Sbjct: 2087 LESHQSECLHCIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLT 2146

Query: 342  NKELENKLATMGTESKAVSSPSKKGSPLISRKSGR--NTASKMKSPWSQLSSETLN-QDT 398
              ELEN++A +  E + +   S+     +S       N +  +++   +     L    T
Sbjct: 2147 KCELENQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSST 2206

Query: 399  DKKIN--KNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEH 456
             ++++  +  I KL + I++  K    K+  I+EK             K   +  L+ E 
Sbjct: 2207 QEEVHQLRRGIEKLRVRIEADEK----KQLHIAEKLKERERENDSLKDK---VENLEREL 2259

Query: 457  QQHMEGPSLIHVGT-NTEDVNEIAKVQ-EQLKQELND-EIKDVNVKDLIEKL-KSAEEQI 512
            Q   E   L+ +   N++   E  K Q E++ + L   E+  V ++   E L K  +E+ 
Sbjct: 2260 QMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQ 2319

Query: 513  TQLN--DEIDAANKNMIKVKSNHKLKLKQMQKTIDNF--SKVSDSNKEIVRLT--EELHH 566
             QL+  D++ ++ K++++ K   ++++K+  KT      +++ + N+ +  L   +E+  
Sbjct: 2320 GQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQEIMK 2379

Query: 567  LSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDL 626
             +++  +   E+ +   + ++    R+ E+D  K++  ++ L E+   A  LL+ +  +L
Sbjct: 2380 ATEQSLDPPIEEEHQLRNSIEKLRARL-EADEKKQLCVLQQLKESEHHA-DLLKGRVENL 2437

Query: 627  VQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLK 686
             +EL I +   +         + L+++    E+++  L+ +I+ ++ S + L L +  ++
Sbjct: 2438 ERELEIARTNQEH--------AALEAENSKGEVET--LKAKIEGMTQSLRGLELDVVTIR 2487

Query: 687  LDKEQLYGTI-KDLENDKE-DIMNK-LQNYIQEN-MDLTDKLEKMSA--EKISELLAKIN 740
             +KE L   + K+ E   E +I+N   +N +QE   +     EK S   E +   L ++N
Sbjct: 2488 SEKENLTNELQKEQERISELEIINSSFENILQEKEQEKVQMKEKSSTAMEMLQTQLKELN 2547

Query: 741  HEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKAD 800
                +    Q    AK Q     +E +E E ++    +   + +  V++     L ++ +
Sbjct: 2548 ERVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVE 2607

Query: 801  QLGSYLQEKQKAYSEYTIQ---EDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQI 857
                 L++K +  S    Q   +++LV++L+ +    ++ ++Q LE+ +   EL++K Q+
Sbjct: 2608 DGKQKLEKKDEEISRLKNQIQDQEQLVSKLSQVEGEHQLWKEQNLELRNLTVELEQKIQV 2667

Query: 858  LLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTL 917
            L  +N +LQ +L  +Q  Y  L  +   T + +    +   ++   E+ L+R  HE    
Sbjct: 2668 LQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEKVNKMTAKETELQREMHEMAQK 2727

Query: 918  IVQKKKEIED----LEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIEN 973
              + ++E+      L  E    +E     K  L E   +N E    L+     +K+ +E 
Sbjct: 2728 TAELQEELSGEKNRLAGELQLLLEEIKSSKDQLKELTLENSELKKSLDCM---HKDQVEK 2784

Query: 974  LNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDE-------EII 1026
                 EE+ +  L L +   +K Q    D  +QY  EI      L  K+E       EI 
Sbjct: 2785 EGKVREEIAEYQLRLHEAE-KKHQALLLDTNKQYEVEIQTYREKLTSKEECLSSQKLEID 2843

Query: 1027 AL---NQKINNAQVSYMSMVSDY-ESKL--AQFTTKLENMEEEMQRVSKQLLDS-KQHNE 1079
             L    +++NN+  +   ++ +  ++K+   ++  +L+   E  Q   K L+ S KQ  E
Sbjct: 2844 LLKSSKEELNNSLKATTQILEELKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCKQLEE 2903

Query: 1080 ELQILVRE----QDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDAN 1126
            E +IL +E    Q  Q K+   T +  +++   TE   +  T+E  + +A+
Sbjct: 2904 EKEILQKELSQLQAAQEKQKTGTVMDTKVDELTTEIKELKETLEEKTKEAD 2954



 Score = 99.1 bits (236), Expect = 9e-19
 Identities = 216/1150 (18%), Positives = 475/1150 (41%), Gaps = 117/1150 (10%)

Query: 463  PSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAA 522
            PS  + G+  ED+ E    + + ++ L  E+K +  K   + L  A      +N      
Sbjct: 155  PSQYYSGSKYEDLKEKYNKEVEERKRLEAEVKALQAKKASQTLPQA-----TMN------ 203

Query: 523  NKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQ 582
            ++++ + +++  +   Q +KT  + S  S+S +  +R      + S +  E+   +  LQ
Sbjct: 204  HRDIARHQASSSVFSWQQEKTPSHLS--SNSQRTPIRRDFSASYFSGE-QEVTPSRSTLQ 260

Query: 583  LHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVED 642
            +   D +S     S     + +++   +     I+ LE +     +E+     K+ E++ 
Sbjct: 261  IGKRDANSSFFDNSSSPHLLDQLKAQNQELRNKINELELRLQGHEKEMKGQVNKFQELQL 320

Query: 643  KL--ADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLE 700
            +L  A +  ++ ++V ++ +   +        AS K  AL  + LK   E L    ++ E
Sbjct: 321  QLEKAKVELIEKEKVLNKCRDELVRTTAQYDQASTKYTALE-QKLKKLTEDLSCQRQNAE 379

Query: 701  NDKEDIMNKL---QNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKI 757
            + +  +  K+   +   QE +    +  +   ++  ++ A++  E Q        + A++
Sbjct: 380  SARCSLEQKIKEKEKEFQEELSRQQRSFQTLDQECIQMKARLTQELQQAKNMHNVLQAEL 439

Query: 758  QERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQL---GSYLQ--EKQKA 812
             +     + +E+ L ++K ++CR E++    + +   L R  +++    + L+   +QKA
Sbjct: 440  DKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKA 499

Query: 813  YSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDM 872
              E    E EL N    L       E+  ++ ++ ++E   ++   L+E  N Q +   +
Sbjct: 500  -REVCHLEAELKNIKQCLNQSQNFAEE--MKAKNTSQETMLRD---LQEKINQQENSLTL 553

Query: 873  QQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQ---KKKEIEDLE 929
            ++   A+ +   + D ++    K +  +  L   L +   E + L+     KKKE E+L+
Sbjct: 554  EKLKLAVADLEKQRDCSQDLLKKREHHIEQLNDKLSKTEKESKALLSALELKKKEYEELK 613

Query: 930  IEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELI 989
                        +K + +    +N + +TQ+E++ +  ++ I +L         +  + I
Sbjct: 614  -----------EEKTLFSCWKSENEKLLTQMESEKENLQSKINHLE------TCLKTQQI 656

Query: 990  DKHVQKQQTQSPDYTEQYIN-EINKLNALLKQKDEEI-------IALNQKINNAQVSYMS 1041
              H   ++ ++ +   + ++ EI  L+ +L  K  E+       + L QK   +   +  
Sbjct: 657  KSHEYNERVRTLEMDRENLSVEIRNLHNVLDSKSVEVETQKLAYMELQQKAEFSDQKHQK 716

Query: 1042 MVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLT 1101
             + +   K +Q T ++E++E ++Q +S +++D  +  ++L        D +K  K+  L 
Sbjct: 717  EIENMCLKTSQLTGQVEDLEHKLQLLSNEIMDKDRCYQDLHAEYESLRDLLKS-KDASLV 775

Query: 1102 FEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEE-----FIQER-- 1154
               N      ++       M     N+              +++ ++       +Q R  
Sbjct: 776  --TNEDHQRSLLAFDQQPAMHHSFANIIGEQGSMPSERSECRLEADQSPKNSAILQNRVD 833

Query: 1155 --SVLQEQSAKLNTELQECYTKIIQLE-TLNTELTGHDVVNQEQINQLKSKLEQLNTEND 1211
                  E   ++N++LQ+   +++Q++  +   L   + ++Q  + +   ++ +L  +  
Sbjct: 834  SLEFSLESQKQMNSDLQKQCEELVQIKGEIEENLMKAEQMHQSFVAETSQRISKLQEDTS 893

Query: 1212 NLLSTVAELRSS----------ISSAVDQRGFEIAELWK-QHLAQREADFQKTEHELRVQ 1260
               + VAE  S+          ++  V+    EI EL K  HL +   D  K    L   
Sbjct: 894  AHQNVVAETLSALENKEKELQLLNDKVETEQAEIQELKKSNHLLE---DSLKELQLLSET 950

Query: 1261 LSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQI 1320
            LS  + +   ++   +   +E T +  T++++ +    L  ++ +L    E +A+ I++ 
Sbjct: 951  LSLEKKEMSSIISLNKREIEELTQENGTLKEINA---SLNQEKMNLIQKSESFANYIDER 1007

Query: 1321 EILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQS-----ILNINEENA 1375
            E   SE+ D+                    DL   +Q YK  QE++     +LN      
Sbjct: 1008 EKSISELSDQYKQEKLILLQRCEETGNAYEDL---SQKYKAAQEKNSKLECLLNECTSLC 1064

Query: 1376 QLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFE 1435
            + +K+             +    +    E  +Q  + + E  Q+     +T  Q N + E
Sbjct: 1065 ENRKNELEQLKEAFAKEHQEFLTKLAFAEERNQNLMLELETVQQALRSEMTDNQNNSKSE 1124

Query: 1436 --NVRQQLV-------EYEKRIEDLTYEKESELAILRLKMHENAN-HYETMQ---KESEI 1482
               ++Q+++       + +K + DL  E E  + +++ K HE  N   E ++   KE E 
Sbjct: 1125 AGGLKQEIMTLKEEQNKMQKEVNDLLQENEQLMKVMKTK-HECQNLESEPIRNSVKERES 1183

Query: 1483 ER----VKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLND 1538
            ER     K   +L VK     S N Q+ +L   L  +  K  E +   E  + E+ T+  
Sbjct: 1184 ERNQCNFKPQMDLEVKEISLDSYNAQLVQLEAMLRNKELKLQESEKEKECLQHELQTIRG 1243

Query: 1539 --EITNLQNM 1546
              E +NLQ+M
Sbjct: 1244 DLETSNLQDM 1253



 Score = 89.4 bits (212), Expect = 7e-16
 Identities = 204/1121 (18%), Positives = 462/1121 (41%), Gaps = 106/1121 (9%)

Query: 483  EQLKQELNDEIKDVNVKDLIEKLKSAE-EQITQLNDEIDAANKNMIKVKSNHKLKLKQMQ 541
            E LK++ N E+++   K L  ++K+ + ++ +Q   +    ++++ + +++  +   Q +
Sbjct: 165  EDLKEKYNKEVEER--KRLEAEVKALQAKKASQTLPQATMNHRDIARHQASSSVFSWQQE 222

Query: 542  KTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKK 601
            KT  + S  S+S +  +R      + S +  E+   +  LQ+   D +S     S     
Sbjct: 223  KTPSHLS--SNSQRTPIRRDFSASYFSGE-QEVTPSRSTLQIGKRDANSSFFDNSSSPHL 279

Query: 602  MIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKL--ADISQLQSDQVCSEI 659
            + +++   +     I+ LE +     +E+     K+ E++ +L  A +  ++ ++V ++ 
Sbjct: 280  LDQLKAQNQELRNKINELELRLQGHEKEMKGQVNKFQELQLQLEKAKVELIEKEKVLNKC 339

Query: 660  KSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKL---QNYIQE 716
            +   +        AS K  AL  + LK   E L    ++ E+ +  +  K+   +   QE
Sbjct: 340  RDELVRTTAQYDQASTKYTALE-QKLKKLTEDLSCQRQNAESARCSLEQKIKEKEKEFQE 398

Query: 717  NMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKS 776
             +    +  +   ++  ++ A++  E Q        + A++ +     + +E+ L ++K 
Sbjct: 399  ELSRQQRSFQTLDQECIQMKARLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQ 458

Query: 777  RICRLEESIAVMEDRRYSLERKADQL---GSYLQE--KQKAYSEYTIQEDELVNRLAVLM 831
            ++CR E++    + +   L R  +++    + L+   +QKA  E    E EL N    L 
Sbjct: 459  KLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKA-REVCHLEAELKNIKQCLN 517

Query: 832  DHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAES 891
                  E+  ++ ++ ++E   ++   L+E  N Q +   +++   A+ +   + D ++ 
Sbjct: 518  QSQNFAEE--MKAKNTSQETMLRD---LQEKINQQENSLTLEKLKLAVADLEKQRDCSQD 572

Query: 892  ESTKYQTQLRDLESNLKRITHEHQTLIVQ---KKKEIEDLEIEFNTQIESAIRDKKVLNE 948
               K +  +  L   L +   E + L+     KKKE E+L+ E           K + + 
Sbjct: 573  LLKKREHHIEQLNDKLSKTEKESKALLSALELKKKEYEELKEE-----------KTLFSC 621

Query: 949  KYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYI 1008
               +N + +TQ+E++ +  ++ I +L         +  + I  H   ++ ++ +   + +
Sbjct: 622  WKSENEKLLTQMESEKENLQSKINHLE------TCLKTQQIKSHEYNERVRTLEMDRENL 675

Query: 1009 N-EINKLNALLKQKDEEI-------IALNQKINNAQVSYMSMVSDYESKLAQFTTKLENM 1060
            + EI  L+ +L  K  E+       + L QK   +   +   + +   K +Q T ++E++
Sbjct: 676  SVEIRNLHNVLDSKSVEVETQKLAYMELQQKAEFSDQKHQKEIENMCLKTSQLTGQVEDL 735

Query: 1061 EEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEP 1120
            E ++Q +S +++D  +  ++L        D +K    + +T   N      ++       
Sbjct: 736  EHKLQLLSNEIMDKDRCYQDLHAEYESLRDLLKSKDASLVT---NEDHQRSLLAFDQQPA 792

Query: 1121 MSDDANNVDXXXXXXXXXXXXLKVQEEEE-----FIQER----SVLQEQSAKLNTELQEC 1171
            M     N+              +++ ++       +Q R        E   ++N++LQ+ 
Sbjct: 793  MHHSFANIIGEQGSMPSERSECRLEADQSPKNSAILQNRVDSLEFSLESQKQMNSDLQKQ 852

Query: 1172 YTKIIQLE-TLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSA--- 1227
              +++Q++  +   L   + ++Q  + +   ++ +L  +     + VAE  S++ +    
Sbjct: 853  CEELVQIKGEIEENLMKAEQMHQSFVAETSQRISKLQEDTSAHQNVVAETLSALENKEKE 912

Query: 1228 -------VDQRGFEIAELWKQ-HLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSST 1279
                   V+    EI EL K  HL +   D  K    L   LS  + +   ++   +   
Sbjct: 913  LQLLNDKVETEQAEIQELKKSNHLLE---DSLKELQLLSETLSLEKKEMSSIISLNKREI 969

Query: 1280 QEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXX 1339
            +E T +  T++++ +    L  ++ +L    E +A+ I++ E   SE+ D+         
Sbjct: 970  EELTQENGTLKEINA---SLNQEKMNLIQKSESFANYIDEREKSISELSDQYKQEKLILL 1026

Query: 1340 XXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAE 1399
                       DL   +Q YK  QE+     N +   L                ++ +A 
Sbjct: 1027 QRCEETGNAYEDL---SQKYKAAQEK-----NSKLECLLNECTSLCENRKNELEQLKEAF 1078

Query: 1400 AKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESEL 1459
            AK     HQ E      + +     + L     E E V+Q L      + D     +SE 
Sbjct: 1079 AK----EHQ-EFLTKLAFAEERNQNLML-----ELETVQQAL---RSEMTDNQNNSKSEA 1125

Query: 1460 AILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKT 1519
              L+ ++         MQKE      +  + + V  T+    N +   +  +++E  ++ 
Sbjct: 1126 GGLKQEIMTLKEEQNKMQKEVNDLLQENEQLMKVMKTKHECQNLESEPIRNSVKERESER 1185

Query: 1520 NEM----QTALENQEIEIVTLNDEITNLQNMVRASSSKIQK 1556
            N+     Q  LE +EI + + N ++  L+ M+R    K+Q+
Sbjct: 1186 NQCNFKPQMDLEVKEISLDSYNAQLVQLEAMLRNKELKLQE 1226



 Score = 87.4 bits (207), Expect = 3e-15
 Identities = 184/929 (19%), Positives = 377/929 (40%), Gaps = 74/929 (7%)

Query: 681  VIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKIN 740
            +++ LK   ++L   I +LE   +    +++  + +  +L  +LEK   E I E    +N
Sbjct: 279  LLDQLKAQNQELRNKINELELRLQGHEKEMKGQVNKFQELQLQLEKAKVELI-EKEKVLN 337

Query: 741  HEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRI-CRLEESIAVMEDRRYSLERKA 799
                  ++T     A+  +       +E +L K    + C+ + +    E  R SLE+K 
Sbjct: 338  KCRDELVRT----TAQYDQASTKYTALEQKLKKLTEDLSCQRQNA----ESARCSLEQK- 388

Query: 800  DQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILL 859
                  ++EK+K + E      EL  +       D+   +    +  E ++ +  + +L 
Sbjct: 389  ------IKEKEKEFQE------ELSRQQRSFQTLDQECIQMKARLTQELQQAKNMHNVLQ 436

Query: 860  EENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIV 919
             E   L      ++ +     +K  R + A   S   + +LR     +K+  +  ++   
Sbjct: 437  AELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSE 496

Query: 920  QKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVE 979
            QK +E+  LE E     +   + +    E   KN    T L   LQE  N  EN ++ +E
Sbjct: 497  QKAREVCHLEAELKNIKQCLNQSQNFAEEMKAKNTSQETMLR-DLQEKINQQEN-SLTLE 554

Query: 980  ELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSY 1039
               K+ L + D  ++KQ+  S D  ++  + I +LN  L + ++E  AL   +   +  Y
Sbjct: 555  ---KLKLAVAD--LEKQRDCSQDLLKKREHHIEQLNDKLSKTEKESKALLSALELKKKEY 609

Query: 1040 MSMVSD---YESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELK 1096
              +  +   +    ++    L  ME E + +  ++   +   +  QI   E +++++ L+
Sbjct: 610  EELKEEKTLFSCWKSENEKLLTQMESEKENLQSKINHLETCLKTQQIKSHEYNERVRTLE 669

Query: 1097 ETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSV 1156
              +    + I     ++ S ++E  +     ++             K  E E    + S 
Sbjct: 670  MDRENLSVEIRNLHNVLDSKSVEVETQKLAYMELQQKAEFSDQKHQK--EIENMCLKTSQ 727

Query: 1157 LQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLST 1216
            L  Q   L  +LQ    +I+  +    +L       +   + LKSK   L T  D+  S 
Sbjct: 728  LTGQVEDLEHKLQLLSNEIMDKDRCYQDLHAE---YESLRDLLKSKDASLVTNEDHQRSL 784

Query: 1217 VA-----ELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQL 1271
            +A      +  S ++ + ++G   +E  +  L   EAD Q  ++      +  +++ + L
Sbjct: 785  LAFDQQPAMHHSFANIIGEQGSMPSERSECRL---EAD-QSPKNS-----AILQNRVDSL 835

Query: 1272 LDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEK 1331
              S++S  Q  ++     E++  ++ ++   EE+L   ++ +   + +     S+++++ 
Sbjct: 836  EFSLESQKQMNSDLQKQCEELVQIKGEI---EENLMKAEQMHQSFVAETSQRISKLQEDT 892

Query: 1332 VAFXXXXXXXXXXXXXXXXDLRTENQSYK----QMQEQSILN--INEENAQLKKSSXXXX 1385
             A                 +L+  N   +    ++QE    N  + +   +L+  S    
Sbjct: 893  SAHQNVVAETLSALENKEKELQLLNDKVETEQAEIQELKKSNHLLEDSLKELQLLSETLS 952

Query: 1386 XXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYE 1445
                     ++  + ++ ELT +      EI    ++  + L Q+++ F N    + E E
Sbjct: 953  LEKKEMSSIISLNKREIEELTQENGTL-KEINASLNQEKMNLIQKSESFAN---YIDERE 1008

Query: 1446 KRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQV 1505
            K I +L+ + + E  IL  +  E  N YE + ++ +  + K   +L   + E  SL +  
Sbjct: 1009 KSISELSDQYKQEKLILLQRCEETGNAYEDLSQKYKAAQEK-NSKLECLLNECTSLCENR 1067

Query: 1506 AELNKALEEEVAKTN-EMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKH-VSFASD 1563
                + L+E  AK + E  T L   E     L  E+  +Q  +R+  +  Q +  S A  
Sbjct: 1068 KNELEQLKEAFAKEHQEFLTKLAFAEERNQNLMLELETVQQALRSEMTDNQNNSKSEAGG 1127

Query: 1564 TKQG----RDEQLDNTMNKELLDAVPRAE 1588
             KQ     ++EQ  N M KE+ D +   E
Sbjct: 1128 LKQEIMTLKEEQ--NKMQKEVNDLLQENE 1154



 Score = 81.4 bits (192), Expect = 2e-13
 Identities = 226/1233 (18%), Positives = 519/1233 (42%), Gaps = 133/1233 (10%)

Query: 381  KMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXX 440
            ++++  ++L       + + K   N+  +L++ ++    +L++KE V+++          
Sbjct: 289  ELRNKINELELRLQGHEKEMKGQVNKFQELQLQLEKAKVELIEKEKVLNKCRDELVRTTA 348

Query: 441  XXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQ---ELNDEIKDVN 497
                  T    L+ + ++  E  S       +   +   K++E+ K+   EL+ + +   
Sbjct: 349  QYDQASTKYTALEQKLKKLTEDLSCQRQNAESARCSLEQKIKEKEKEFQEELSRQQRSFQ 408

Query: 498  VKD---------LIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFS 548
              D         L ++L+ A+     L  E+D       ++++N +   +++ +    F 
Sbjct: 409  TLDQECIQMKARLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQKLCRAEQAFQ 468

Query: 549  KVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENL 608
                   E+ R  EE+   +  +    E+K     HL           ++ + + + +N 
Sbjct: 469  ASQIKENELRRSMEEMKKENNLLKSHSEQKAREVCHL------EAELKNIKQCLNQSQNF 522

Query: 609  AETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEI----KSVHL 664
            AE      +  E+   DL ++++  +      + KLA ++ L+  + CS+     +  H+
Sbjct: 523  AEEMKAKNTSQETMLRDLQEKINQQENSLTLEKLKLA-VADLEKQRDCSQDLLKKREHHI 581

Query: 665  EEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKL 724
            E+  D LS ++KE   ++  L+L K       K+ E  KE+       +  EN  L   L
Sbjct: 582  EQLNDKLSKTEKESKALLSALELKK-------KEYEELKEE-KTLFSCWKSENEKL---L 630

Query: 725  EKMSAEKISELLAKINHEEQSKIQTQ----FGIDAKIQERDLYIENIESELSKYKSRICR 780
             +M +EK   L +KINH E   ++TQ       + +++  ++  EN+  E+    + +  
Sbjct: 631  TQMESEK-ENLQSKINHLETC-LKTQQIKSHEYNERVRTLEMDRENLSVEIRNLHNVLDS 688

Query: 781  LEESIAVMEDRRYSLERKADQLGSYLQEKQKAY----SEYTIQEDELVNRLAVL----MD 832
                +   +     L++KA+      Q++ +      S+ T Q ++L ++L +L    MD
Sbjct: 689  KSVEVETQKLAYMELQQKAEFSDQKHQKEIENMCLKTSQLTGQVEDLEHKLQLLSNEIMD 748

Query: 833  HDRVVEKQLLEIEHEN-KELQKKNQILLEENQNLQISLSDMQQ----HY---NALVEKAN 884
             DR  +   L  E+E+ ++L K     L  N++ Q SL    Q    H+   N + E+ +
Sbjct: 749  KDRCYQD--LHAEYESLRDLLKSKDASLVTNEDHQRSLLAFDQQPAMHHSFANIIGEQGS 806

Query: 885  ----RTD--LAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIES 938
                R++  L   +S K    L++   +L+      + +    +K+ E+L ++   +IE 
Sbjct: 807  MPSERSECRLEADQSPKNSAILQNRVDSLEFSLESQKQMNSDLQKQCEEL-VQIKGEIEE 865

Query: 939  AIRDKKVLNEKY-EKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQ 997
             +   + +++ +  +  + +++L+     ++N +      +E   K  L+L++  V+ +Q
Sbjct: 866  NLMKAEQMHQSFVAETSQRISKLQEDTSAHQNVVAETLSALENKEK-ELQLLNDKVETEQ 924

Query: 998  TQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKL 1057
             +        I E+ K N LL+   +E+  L++ ++  +    S++S  + ++ + T + 
Sbjct: 925  AE--------IQELKKSNHLLEDSLKELQLLSETLSLEKKEMSSIISLNKREIEELTQEN 976

Query: 1058 ENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKEL----KETKLTFEMNIPKTEGMI 1113
              ++E    ++++ ++  Q +E     + E++  I EL    K+ KL       +T    
Sbjct: 977  GTLKEINASLNQEKMNLIQKSESFANYIDEREKSISELSDQYKQEKLILLQRCEETGNAY 1036

Query: 1114 I------------SSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQS 1161
                         +S +E + ++  ++                +E +EF+ + +  +E++
Sbjct: 1037 EDLSQKYKAAQEKNSKLECLLNECTSLCENRKNELEQLKEAFAKEHQEFLTKLAFAEERN 1096

Query: 1162 AKLNTELQECYTKIIQLETLNTELTGHDVVN-QEQINQLKSKLEQLNTENDNLLSTVAEL 1220
              L  EL+     +    T N   +  +    +++I  LK +  ++  E ++LL    +L
Sbjct: 1097 QNLMLELETVQQALRSEMTDNQNNSKSEAGGLKQEIMTLKEEQNKMQKEVNDLLQENEQL 1156

Query: 1221 RSSISSAVDQRGFEIAELWKQHLAQREADFQ----KTEHELRVQLSAFESKYEQLLDSVQ 1276
               + +  + +  E +E  +  + +RE++      K + +L V+  + +S   QL+    
Sbjct: 1157 MKVMKTKHECQNLE-SEPIRNSVKERESERNQCNFKPQMDLEVKEISLDSYNAQLVQLEA 1215

Query: 1277 SSTQEETNKIVTMEQVTSLQNKLQDKEEHLR--NLQEKYADVINQIEILRSEIEDEKVAF 1334
                +E     + ++   LQ++LQ     L   NLQ+  +  I+ ++    + E++ ++ 
Sbjct: 1216 MLRNKELKLQESEKEKECLQHELQTIRGDLETSNLQDMQSQEISGLKDCEIDAEEKYIS- 1274

Query: 1335 XXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXR 1394
                            +L T       +Q      +N+ N +L+K               
Sbjct: 1275 -------------GPHELSTSQNDNAHLQCSLQTTMNKLN-ELEKICEILQAEKYELVTE 1320

Query: 1395 VNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYE 1454
            +ND+ ++ +  T ++     E+ +  +E  I     ND+   +  +LVE     E    E
Sbjct: 1321 LNDSRSECITATRKMA---EEVGKLLNEVKIL----NDDSGLLHGELVEDIPGGE--FGE 1371

Query: 1455 KESELAILRLKMHENANHYETM---QKESEIERVKLIEELNVKITESVSLNKQVAELNKA 1511
            + +E   + L   + +N YE +    KE ++   +L E+     +E   L+ Q  +++  
Sbjct: 1372 QPNEQHPVSLAPLDESNSYEHLTLSDKEVQMHFAELQEKFLSLQSEHKILHDQHCQMS-- 1429

Query: 1512 LEEEVAKTNEMQTALENQEIEIVTLNDEITNLQ 1544
                 +K +E+QT +++ + E + L+  + N Q
Sbjct: 1430 -----SKMSELQTYVDSLKAENLVLSTNLRNFQ 1457



 Score = 81.0 bits (191), Expect = 2e-13
 Identities = 167/797 (20%), Positives = 350/797 (43%), Gaps = 80/797 (10%)

Query: 233  KDEKQRLLKDIESKDVRISSLEE-----ANKLLEAARFEISLEHSKLAQELEQXXXXXXX 287
            ++E  +L + IE   VRI + E+     A KL E  R   SL+     + LE+       
Sbjct: 2207 QEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDK--VENLERELQMSEE 2264

Query: 288  XXXXXXXLAKQSIEPSCEEKTEIEEKG-SLEIANMTELTKKIELLEHLNCQIRQTNKELE 346
                    A+ S       KT+IEE   SL++  +  +T + E  E+L  QI++   +L 
Sbjct: 2265 NQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEK-ENLTKQIQEKQGQL- 2322

Query: 347  NKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNE 406
            ++L  + +  K++    ++    I  +S +     +++   +L+        D++I K  
Sbjct: 2323 SELDKLLSSFKSLLEEKEQAEIQIKEES-KTAVEMLQNQLKELNEAVAALCGDQEIMKAT 2381

Query: 407  IAKLEMVIQSLN--KDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQL------QLEHQQ 458
               L+  I+  +  ++ ++K     E D            +    A L       LE + 
Sbjct: 2382 EQSLDPPIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRVENLEREL 2441

Query: 459  HMEGPSLIHVGTNTE----DVNEIAKVQEQLKQELND-EIKDVNVK----DLIEKLKSAE 509
             +   +  H     E    +V  +    E + Q L   E+  V ++    +L  +L+  +
Sbjct: 2442 EIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTNELQKEQ 2501

Query: 510  EQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQ 569
            E+I++L + I+++ +N+++ K   K+++K+   T      +    KE+      LH+  Q
Sbjct: 2502 ERISEL-EIINSSFENILQEKEQEKVQMKEKSSTA--MEMLQTQLKELNERVAALHN-DQ 2557

Query: 570  KVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQE 629
            +  + +E+  + Q+  ++ +  ++++            L E +   I +L+S    L+QE
Sbjct: 2558 EACKAKEQNLSSQVECLELEKAQLLQG-----------LDEAKNNYI-VLQSSVNGLIQE 2605

Query: 630  LHILQQKYDEVEDKLADI-SQLQS-DQVCSEIKSVHLEEQIDALSASKKELALVIENLKL 687
            +   +QK ++ +++++ + +Q+Q  +Q+ S++  V  E Q+       KE  L + NL +
Sbjct: 2606 VEDGKQKLEKKDEEISRLKNQIQDQEQLVSKLSQVEGEHQL------WKEQNLELRNLTV 2659

Query: 688  DKEQLYGTIKDLENDKEDIMNKLQNY---IQENMDLTDKLEKMS-AEKISELLAKINHEE 743
            + EQ    ++      +D +  LQ+    ++  ++LT K++KMS  EK++++ AK   E 
Sbjct: 2660 ELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELT-KMDKMSFVEKVNKMTAK-ETEL 2717

Query: 744  QSKIQTQFGIDAKIQERDLYIEN-IESELSKYKSRICRLEESIAVMEDRRYSLERKADQL 802
            Q ++       A++QE     +N +  EL      I   ++ +  +      L++  D +
Sbjct: 2718 QREMHEMAQKTAELQEELSGEKNRLAGELQLLLEEIKSSKDQLKELTLENSELKKSLDCM 2777

Query: 803  GSYLQEKQ----KAYSEYTIQEDELVNR-LAVLMDHDRVVEKQLLEIEHENKELQKKNQI 857
                 EK+    +  +EY ++  E   +  A+L+D ++  E   +EI+   ++L  K + 
Sbjct: 2778 HKDQVEKEGKVREEIAEYQLRLHEAEKKHQALLLDTNKQYE---VEIQTYREKLTSKEEC 2834

Query: 858  LLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQT--QLRDLESNLKRITHEHQ 915
            L  +   + +  S  ++  N+L  KA    L E + TK      +  L+   +R   + +
Sbjct: 2835 LSSQKLEIDLLKSSKEELNNSL--KATTQILEELKKTKMDNLKYVNQLKKENERAQGKMK 2892

Query: 916  TLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLN 975
             LI   K+  E+ EI     ++  +   +   EK +      T ++ ++ E    I+ L 
Sbjct: 2893 LLIKSCKQLEEEKEI-----LQKELSQLQAAQEKQKTG----TVMDTKVDELTTEIKELK 2943

Query: 976  MNVEELNKMNLELIDKH 992
              +EE  K   E +DK+
Sbjct: 2944 ETLEEKTKEADEYLDKY 2960



 Score = 79.8 bits (188), Expect = 6e-13
 Identities = 165/839 (19%), Positives = 363/839 (43%), Gaps = 101/839 (12%)

Query: 764  IENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDEL 823
            I N++  + +  +   RL   + V+EDR    +RK + L   L E ++  S+  +QE +L
Sbjct: 1865 IHNLQLRVKETSNENLRL---LHVIEDR----DRKVESL---LNEMKELDSKLHLQEVQL 1914

Query: 824  VNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNL--QISLSD-MQQHYNALV 880
            + ++   ++ +++V     E++ EN +L +K +    ++Q L  ++  S+ +        
Sbjct: 1915 MTKIEACIELEKIVG----ELKKENSDLSEKLEYFSCDHQELLQRVETSEGLNSDLEMHA 1970

Query: 881  EKANRTDLAESEST---KYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIE 937
            +K++R D+ ++ +     ++ +  D+E+ L RI  E        K  IE   +     +E
Sbjct: 1971 DKSSREDIGDNVAKVNDSWKERFLDVENELSRIRSE--------KASIEHEALYLEADLE 2022

Query: 938  SAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMN--LELIDKHVQK 995
                +K  L +  E   + +  LE +L    +    L   ++ ++K    L+ + + +++
Sbjct: 2023 VVQTEKLCLEKDNENKQKVIVCLEEELSVVTSERNQLRGELDTMSKKTTALDQLSEKMKE 2082

Query: 996  QQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTT 1055
            +  +   +  + ++ I    A +K+K E +  L+           S VS+          
Sbjct: 2083 KTQELESHQSECLHCIQVAEAEVKEKTELLQTLS-----------SDVSELLKDKTHLQE 2131

Query: 1056 KLENMEEEMQRVS--KQLLDSK--QHNEELQILVREQDDQIKELKETKLTFEMNIPKT-E 1110
            KL+++E++ Q +S  K  L+++  Q N+E ++LV+E +     L E+    ++N+ K  E
Sbjct: 2132 KLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLSESDYE-KLNVSKALE 2190

Query: 1111 GMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEE---FIQERSVLQEQSAKLNTE 1167
              ++      +   +   +            ++++ +E+    I E+   +E+      +
Sbjct: 2191 AALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKD 2250

Query: 1168 LQECYTKIIQLETLNTELTGHDVVNQE-QINQLKSKLEQLNTENDNLLSTVAELRS---S 1223
              E   + +Q+   N EL   D  N + ++  LK+++E++          +  LRS   +
Sbjct: 2251 KVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKEN 2310

Query: 1224 ISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEET 1283
            ++  + ++  +++EL K   + +    +K + E++++    ESK    ++ +Q+  +E  
Sbjct: 2311 LTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKE---ESK--TAVEMLQNQLKELN 2365

Query: 1284 NKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIE-DEKVAFXXXXXXXX 1342
              +  +      Q  ++  E+ L    E+   + N IE LR+ +E DEK           
Sbjct: 2366 EAVAAL---CGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKE 2422

Query: 1343 XXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKV 1402
                      R EN      +E  I   N+E+A L+  +             V   +AK+
Sbjct: 2423 SEHHADLLKGRVENLE----RELEIARTNQEHAALEAENSKG---------EVETLKAKI 2469

Query: 1403 LELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAIL 1462
              +T  L   + ++          +T R+++ EN+  +L + ++RI +L     S   IL
Sbjct: 2470 EGMTQSLRGLELDV----------VTIRSEK-ENLTNELQKEQERISELEIINSSFENIL 2518

Query: 1463 RLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEM 1522
            + K  E     +   KE     +++++      T+   LN++VA L+   E   AK   +
Sbjct: 2519 QEKEQE-----KVQMKEKSSTAMEMLQ------TQLKELNERVAALHNDQEACKAKEQNL 2567

Query: 1523 QTALENQEIEIVTL---NDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNK 1578
             + +E  E+E   L    DE  N   ++++S + + + V       + +DE++    N+
Sbjct: 2568 SSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQ 2626



 Score = 71.3 bits (167), Expect = 2e-10
 Identities = 200/1146 (17%), Positives = 446/1146 (38%), Gaps = 124/1146 (10%)

Query: 58   QKCLENAALVSKRIKE----HRKATAELLGRPFVPGISESLANTLKQKEILMEKIKQYKE 113
            Q+C++  A +++ +++    H    AEL     V    E+     KQK    E+  Q  +
Sbjct: 412  QECIQMKARLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQ 471

Query: 114  LSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIK-------EKDNALSVLQVKMK 166
            + +      +                +  +V HL   +K       +  N    ++ K  
Sbjct: 472  IKENELRRSMEEMKKENNLLKSHSEQKAREVCHLEAELKNIKQCLNQSQNFAEEMKAKNT 531

Query: 167  IMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFI 226
              ET + DLQEKIN+++      N  T                  +D  ++     E   
Sbjct: 532  SQETMLRDLQEKINQQE------NSLTLEKLKLAVADLEKQRDCSQDLLKKREHHIEQLN 585

Query: 227  AMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXX 286
               ++ + E + LL  +E K      L+E   L    +     E+ KL  ++E       
Sbjct: 586  DKLSKTEKESKALLSALELKKKEYEELKEEKTLFSCWK----SENEKLLTQMES------ 635

Query: 287  XXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIEL-LEHLNCQIRQTNKEL 345
                      K++++          +   ++     E  + +E+  E+L+ +IR  +  L
Sbjct: 636  ---------EKENLQSKINHLETCLKTQQIKSHEYNERVRTLEMDRENLSVEIRNLHNVL 686

Query: 346  ENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKN 405
            ++K   + T+  A     +K     S +  +     M    SQL+ +  + +   ++  N
Sbjct: 687  DSKSVEVETQKLAYMELQQKAE--FSDQKHQKEIENMCLKTSQLTGQVEDLEHKLQLLSN 744

Query: 406  EIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSL 465
            EI   +   Q L+ +      ++  KD            +D   + L  + Q  M     
Sbjct: 745  EIMDKDRCYQDLHAEYESLRDLLKSKD------ASLVTNEDHQRSLLAFDQQPAMHHSFA 798

Query: 466  IHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKN 525
              +G      +E ++ + +  Q   +      +++ ++ L+ + E   Q+N ++    + 
Sbjct: 799  NIIGEQGSMPSERSECRLEADQSPKN---SAILQNRVDSLEFSLESQKQMNSDLQKQCEE 855

Query: 526  MIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHL 585
            ++++K   +  L + ++   +F  V+++++ I +L E+       VAE      N +  L
Sbjct: 856  LVQIKGEIEENLMKAEQMHQSF--VAETSQRISKLQEDTSAHQNVVAETLSALENKEKEL 913

Query: 586  VDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLA 645
                  +++   V  +  E++ L     K+  LLE    D ++EL +L +     + +++
Sbjct: 914  ------QLLNDKVETEQAEIQELK----KSNHLLE----DSLKELQLLSETLSLEKKEMS 959

Query: 646  DISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKED 705
             I  L   ++          E++   + + KE+   +   K++  Q   +  +  +++E 
Sbjct: 960  SIISLNKREI----------EELTQENGTLKEINASLNQEKMNLIQKSESFANYIDEREK 1009

Query: 706  IMNKLQN-YIQENMDLTDKLEKM--SAEKISELLAKINHEEQSKIQTQFGIDAKIQERDL 762
             +++L + Y QE + L  + E+   + E +S+   K   E+ SK      ++  + E   
Sbjct: 1010 SISELSDQYKQEKLILLQRCEETGNAYEDLSQKY-KAAQEKNSK------LECLLNECTS 1062

Query: 763  YIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDE 822
              EN ++EL + K    +  E    +    ++ ER  + +      +Q   SE T  ++ 
Sbjct: 1063 LCENRKNELEQLKEAFAK--EHQEFLTKLAFAEERNQNLMLELETVQQALRSEMTDNQNN 1120

Query: 823  LVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEK 882
              +    L       +++++ ++ E  ++QK+   LL+EN+ L   +    +  N     
Sbjct: 1121 SKSEAGGL-------KQEIMTLKEEQNKMQKEVNDLLQENEQLMKVMKTKHECQNL---- 1169

Query: 883  ANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRD 942
                     ES   +  +++ ES   +   + Q  +  K+  ++    +   Q+E+ +R+
Sbjct: 1170 ---------ESEPIRNSVKERESERNQCNFKPQMDLEVKEISLDSYNAQL-VQLEAMLRN 1219

Query: 943  KKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNM-NVEELNKMNLELIDKHVQKQQTQSP 1001
            K++  ++ EK  E    L+ +LQ  + ++E  N+ +++      L+  +   +++    P
Sbjct: 1220 KELKLQESEKEKEC---LQHELQTIRGDLETSNLQDMQSQEISGLKDCEIDAEEKYISGP 1276

Query: 1002 DYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENME 1061
                   N+   L   L+    ++  L +     Q     +V++     ++  T    M 
Sbjct: 1277 HELSTSQNDNAHLQCSLQTTMNKLNELEKICEILQAEKYELVTELNDSRSECITATRKMA 1336

Query: 1062 EEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPM 1121
            EE   V K L + K  N++  +L         EL E     E      E   +S  + P+
Sbjct: 1337 EE---VGKLLNEVKILNDDSGLL-------HGELVEDIPGGEFGEQPNEQHPVS--LAPL 1384

Query: 1122 SDDANNVDXXXXXXXXXXXXLKVQEEEEFIQ-ERSVLQEQSAKLNTELQECYTKIIQLET 1180
             +  +                ++QE+   +Q E  +L +Q  ++++++ E  T +  L+ 
Sbjct: 1385 DESNSYEHLTLSDKEVQMHFAELQEKFLSLQSEHKILHDQHCQMSSKMSELQTYVDSLKA 1444

Query: 1181 LNTELT 1186
             N  L+
Sbjct: 1445 ENLVLS 1450



 Score = 71.3 bits (167), Expect = 2e-10
 Identities = 141/730 (19%), Positives = 305/730 (41%), Gaps = 55/730 (7%)

Query: 143  DVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXX 202
            +V  L   I+E   +L V ++ +  + +   +L ++I EK   +   +K  +        
Sbjct: 2279 EVETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEE 2338

Query: 203  XXXXXXXXXEDTKQQMTKMQENFIAMEAEWKD--EKQRLLKDIE-SKDVRISSLEEANKL 259
                     E++K  +  +Q     +          Q ++K  E S D  I    +    
Sbjct: 2339 KEQAEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIEEEHQLRNS 2398

Query: 260  LEAARFEISLEHSK---LAQELEQXXXXXXXXXXXXXXLAKQ-SIEPSCEEKTEIE---E 312
            +E  R  +  +  K   + Q+L++              L ++  I  + +E   +E    
Sbjct: 2399 IEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRVENLERELEIARTNQEHAALEAENS 2458

Query: 313  KGSLEI--ANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLI 370
            KG +E   A +  +T+ +  LE     IR   + L N+L         +   +     ++
Sbjct: 2459 KGEVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTNELQKEQERISELEIINSSFENIL 2518

Query: 371  SRKSGRNTASKMKSPWSQLSSETLNQDTDKKI----NKNEIAKL-EMVIQSLNKDL-VDK 424
              K       K KS  +    +T  ++ ++++    N  E  K  E  + S  + L ++K
Sbjct: 2519 QEKEQEKVQMKEKSSTAMEMLQTQLKELNERVAALHNDQEACKAKEQNLSSQVECLELEK 2578

Query: 425  EYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQ-HMEGPSLIHVGTNTED----VNEIA 479
              ++   D             + LI +++   Q+   +   +  +    +D    V++++
Sbjct: 2579 AQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEQLVSKLS 2638

Query: 480  KVQ--EQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKL 537
            +V+   QL +E N E++++ V +L +K++  + +   L D ++    +   +++  +L+L
Sbjct: 2639 QVEGEHQLWKEQNLELRNLTV-ELEQKIQVLQSKNASLQDTLEVLQSSYKNLEN--ELEL 2695

Query: 538  KQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESD 597
             +M K +    KV+    +   L  E+H ++QK AEL+EE    +  L       + E  
Sbjct: 2696 TKMDK-MSFVEKVNKMTAKETELQREMHEMAQKTAELQEELSGEKNRLAGELQLLLEEIK 2754

Query: 598  VYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCS 657
              K  ++   L  + LK    L+    D V++   ++++  E + +L +  +     +  
Sbjct: 2755 SSKDQLKELTLENSELK--KSLDCMHKDQVEKEGKVREEIAEYQLRLHEAEKKHQALLLD 2812

Query: 658  EIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQEN 717
              K   +E Q      + KE  L  + L++D          L++ KE++ N L+   Q  
Sbjct: 2813 TNKQYEVEIQTYREKLTSKEECLSSQKLEIDL---------LKSSKEELNNSLKATTQIL 2863

Query: 718  MDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSR 777
             +L  K  KM   K    L K N   Q K++       +++E     E ++ ELS+ ++ 
Sbjct: 2864 EEL--KKTKMDNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEK---EILQKELSQLQAA 2918

Query: 778  ICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNR-LAVLMDHDRV 836
              + +++  VM+        K D+L + ++E ++   E T + DE +++  ++L+ H+++
Sbjct: 2919 QEK-QKTGTVMDT-------KVDELTTEIKELKETLEEKTKEADEYLDKYCSLLISHEKL 2970

Query: 837  VE-KQLLEIE 845
             + K++LE +
Sbjct: 2971 EKAKEMLETQ 2980



 Score = 37.9 bits (84), Expect = 2.3
 Identities = 90/601 (14%), Positives = 229/601 (38%), Gaps = 14/601 (2%)

Query: 958  TQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNAL 1017
            T+   ++QE +  ++ L    ++  +  L+ ++  +QKQ+ +  +   +  N + + N  
Sbjct: 14   TRALQKIQELEGQLDKLKKEKQQ-RQFQLDSLEAALQKQKQKVENEKTEGTN-LKRENQR 71

Query: 1018 LKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQH 1077
            L +  E +    QKI++      S V+  E +L     ++E +E+E++R   +L  S+Q 
Sbjct: 72   LMEICESLEKTKQKISHELQVKESQVNFQEGQLNSGKKQIEKLEQELKRCKSELERSQQA 131

Query: 1078 NEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXX 1137
             +   + +   +   +++  T LT       ++   +        ++   ++        
Sbjct: 132  AQSADVSLNPCNTP-QKIFTTPLTPSQYYSGSKYEDLKEKYNKEVEERKRLEAEVKALQA 190

Query: 1138 XXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKI---IQLETLNTELTGHDVVNQE 1194
                  + +     ++ +  Q  S+  + + ++  + +    Q   +  + +      ++
Sbjct: 191  KKASQTLPQATMNHRDIARHQASSSVFSWQQEKTPSHLSSNSQRTPIRRDFSASYFSGEQ 250

Query: 1195 QINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTE 1254
            ++   +S L Q+   + N  S+  +  SS    +DQ   +  EL +  + + E   Q  E
Sbjct: 251  EVTPSRSTL-QIGKRDAN--SSFFD-NSSSPHLLDQLKAQNQEL-RNKINELELRLQGHE 305

Query: 1255 HELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYA 1314
             E++ Q++ F+    QL  +     ++E       +++     +          L++K  
Sbjct: 306  KEMKGQVNKFQELQLQLEKAKVELIEKEKVLNKCRDELVRTTAQYDQASTKYTALEQKLK 365

Query: 1315 DVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEEN 1374
             +   +   R   E  + +                   +   Q+  Q   Q    + +E 
Sbjct: 366  KLTEDLSCQRQNAESARCSLEQKIKEKEKEFQEELSRQQRSFQTLDQECIQMKARLTQEL 425

Query: 1375 AQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEF 1434
             Q K                    E  + E   +L  +  + +Q +      L +  +E 
Sbjct: 426  QQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQKL-CRAEQAFQASQIKENELRRSMEEM 484

Query: 1435 ENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVK 1494
            +     L  + ++        E+EL  ++  ++++ N  E M K     +  ++ +L  K
Sbjct: 485  KKENNLLKSHSEQKAREVCHLEAELKNIKQCLNQSQNFAEEM-KAKNTSQETMLRDLQEK 543

Query: 1495 ITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKI 1554
            I +  + +  + +L  A+ +   + +  Q  L+ +E  I  LND+++  +   +A  S +
Sbjct: 544  INQQEN-SLTLEKLKLAVADLEKQRDCSQDLLKKREHHIEQLNDKLSKTEKESKALLSAL 602

Query: 1555 Q 1555
            +
Sbjct: 603  E 603


>UniRef50_UPI0001509DA0 Cluster: hypothetical protein TTHERM_00535450;
            n=1; Tetrahymena thermophila SB210|Rep: hypothetical
            protein TTHERM_00535450 - Tetrahymena thermophila SB210
          Length = 1469

 Score =  124 bits (300), Expect = 2e-26
 Identities = 189/898 (21%), Positives = 401/898 (44%), Gaps = 82/898 (9%)

Query: 488  ELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNF 547
            +L  + +D+ +K     ++  E Q+  L +EID  +    ++  ++  K+K ++ TI+N 
Sbjct: 118  QLQSQQEDLKIK-YASDIQQYENQMVSLKNEIDRLSNQQGQINQSNNQKVKNLESTIENK 176

Query: 548  SK-VSDSNKEIV---RLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMI 603
            +  +++  ++I+   +  E+   L+Q+ +   + +       +     + I+S +  ++ 
Sbjct: 177  AAIINELQRQIIDKNQYQEQQIILAQQESSFSKNQSQFLDPQILIIKDQEIQS-IKMQLS 235

Query: 604  EMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVH 663
            EM++    +++A S  E + F+  +   +LQ++  ++  ++  I++  S Q+ S +KS  
Sbjct: 236  EMQSKLNQQIQAFSSQEEENFNQKKANRLLQEENKKLNLQVQQITK-NSSQIESRLKS-- 292

Query: 664  LEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDK 723
              E   + S  K +L  V E LK  K++     + L+N  ++   KLQ   QE M LT++
Sbjct: 293  --ELESSQSILKLQLNEVQEKLKQLKKKHKHKKQLLKNKIKEYEIKLQEMEQEAMILTEQ 350

Query: 724  LEKMSAEKISELLAKINHEEQSKIQTQF-------GIDAKIQERDLYI-ENIESELSKY- 774
                      ++    +H E    Q Q         ++A ++E+ + + +++  +  K  
Sbjct: 351  HRNDKRNLTEQIQITKDHYEYLLQQQQTDMANTLQNMNANLEEQKIKLRQDLTEQFEKQS 410

Query: 775  KSRICRLEESIAVMEDRRYSLERKAD-QLGSY-LQEKQ--------KAYSEYTIQEDELV 824
            K+   + ++ I  ++ R Y +++K D Q+  + +Q KQ          ++   I+ ++L 
Sbjct: 411  KANKQQYDQEIQKLKKREYEIQKKFDEQMHDFVIQNKQIQNNFFQNNDFALVKIENEKLK 470

Query: 825  NRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKAN 884
              LA +   ++     L +  +    L +KN  L E+  NL+  L   +  Y  + ++  
Sbjct: 471  QELASVKTENQFA---LNQQNYTVNNLTEKNDALEEQIVNLKKQLGKQEIEYEKMKKQFE 527

Query: 885  RTDL-AESESTKYQTQLRDLES--NLKRITHEHQTLI------VQKKKEIEDLEIEFNTQ 935
               + +E+ S ++    RD +   N KR   ++  L+      +QKK EI+  E +    
Sbjct: 528  SLKIDSETLSQRFNILQRDKDQAVNEKRQIQKNFDLLEKERNDIQKKLEIKKEEYQNQHI 587

Query: 936  IESAIRDKKVLNEKYEKNIEYVT-QLEAQLQEYKNNIENLNMNVEELN---KMNLELID- 990
            +   + +K  + E+   NI+  T Q++  L    N+ + LNM +E+ N   K+++EL + 
Sbjct: 588  LYERVYEKLNITEQELSNIKNETEQIQTSLFSQINDFKILNMKLEKENEQMKISIELFND 647

Query: 991  -KHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESK 1049
             K   K+Q QS       +NE  KL  L++Q +      +  I+  Q+     + +Y+ +
Sbjct: 648  YKKESKEQIQSLRDENSKVNE--KLVQLIQQNNSNTQEKSSAISQLQIE----LKNYQIQ 701

Query: 1050 LAQFTTKLENMEEEMQ------RVSKQLLDS-KQHNEELQILVREQDDQIK----ELKET 1098
            L     K+E ++EE+Q       V K+ + S ++ + +L+  +R++D+QI     +L+  
Sbjct: 702  LEDKVQKIEKLKEEVQDFKINEEVRKRQIQSLEEQSTDLKQTIRQKDEQINNAQHDLEVY 761

Query: 1099 KLTFEMNIPKTEGMIISSTIEPMSDDANN-------VDXXXXXXXXXXXXLKVQEEEEFI 1151
            K  F++   K +   I        + AN         +            LK   E+  +
Sbjct: 762  KQRFQICKQKLKEAFIQILDSIRLEQANKQLLLKLFEESLKIQFTRSICSLKDNYEDSIL 821

Query: 1152 QERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTEND 1211
              +   Q   + L     E    + Q++ L  ++T     N  +  Q    ++Q+  E  
Sbjct: 822  AIQMYTQGVLSDLKATQNEKSNLVEQIKQLKQQITEQTKQNTARQKQESENMQQIQ-EKS 880

Query: 1212 NLLSTVAELRSSISSAVDQRGFEIAELWK--QHLAQREADFQKTEHELRVQLSAFESKYE 1269
            N LS    ++  IS    +    + E+ K  + + + + D +KT+ E        +S  E
Sbjct: 881  NQLS--KNMKQEISELKKKNNSLLLEIQKSNEKIIEYQLDQKKTKSEKDRMQETIDSLCE 938

Query: 1270 QLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQ--IEILRS 1325
            + +  +Q    E+T KI       S+ N+L+   E L+ L ++  ++  +  I++ RS
Sbjct: 939  E-IKHIQQDNNEKTEKINHWRSQESMSNQLE--MERLQKLCQQELNIYQEKIIQMQRS 993



 Score =  122 bits (294), Expect = 8e-26
 Identities = 191/969 (19%), Positives = 424/969 (43%), Gaps = 73/969 (7%)

Query: 638  DEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIK 697
            DE+ D L    +   D V   IK +  E   D   +  ++L++    +K D + L     
Sbjct: 59   DELIDTLKK-DKTSVDYVQVRIKEIIQECMNDDKESVIEKLSIQYSKIKSDYQLLDEAFN 117

Query: 698  DLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKI 757
             L++ +ED+  K  + IQ+  +    L K   +++S    +IN     K++    +++ I
Sbjct: 118  QLQSQQEDLKIKYASDIQQYENQMVSL-KNEIDRLSNQQGQINQSNNQKVKN---LESTI 173

Query: 758  QERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYT 817
            + +   I  ++ ++        + +E   ++  +  S  +   Q   +L  +     +  
Sbjct: 174  ENKAAIINELQRQIIDKN----QYQEQQIILAQQESSFSKNQSQ---FLDPQILIIKDQE 226

Query: 818  IQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYN 877
            IQ  ++  +L+ +        +     E EN   +K N++L EEN+ L + +  + ++ +
Sbjct: 227  IQSIKM--QLSEMQSKLNQQIQAFSSQEEENFNQKKANRLLQEENKKLNLQVQQITKN-S 283

Query: 878  ALVEKANRTDLAESESTKYQTQLRDLESNLKRIT--HEHQTLIVQKK-KEIE----DLEI 930
            + +E   +++L  S+S   + QL +++  LK++   H+H+  +++ K KE E    ++E 
Sbjct: 284  SQIESRLKSELESSQSI-LKLQLNEVQEKLKQLKKKHKHKKQLLKNKIKEYEIKLQEMEQ 342

Query: 931  EFNTQIESAIRDKKVLNEKYEKNIE-YVTQLEAQLQEYKNNIENLNMNVEELNKMNLELI 989
            E     E    DK+ L E+ +   + Y   L+ Q  +  N ++N+N N+EE     ++L 
Sbjct: 343  EAMILTEQHRNDKRNLTEQIQITKDHYEYLLQQQQTDMANTLQNMNANLEE---QKIKLR 399

Query: 990  DKHVQKQQTQSPDYTEQYINEINKLN----ALLKQKDEEI---IALNQKINN--AQVSYM 1040
                ++ + QS    +QY  EI KL      + K+ DE++   +  N++I N   Q +  
Sbjct: 400  QDLTEQFEKQSKANKQQYDQEIQKLKKREYEIQKKFDEQMHDFVIQNKQIQNNFFQNNDF 459

Query: 1041 SMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQI-KELKETK 1099
            ++V     KL Q   +L +++ E Q    Q   +  +  E    + EQ   + K+L + +
Sbjct: 460  ALVKIENEKLKQ---ELASVKTENQFALNQQNYTVNNLTEKNDALEEQIVNLKKQLGKQE 516

Query: 1100 LTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQ-ERSVLQ 1158
            + +E    + E + I S  E +S   N +              ++Q+  + ++ ER+ +Q
Sbjct: 517  IEYEKMKKQFESLKIDS--ETLSQRFNILQRDKDQAVNEKR--QIQKNFDLLEKERNDIQ 572

Query: 1159 EQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVA 1218
            +   KL  + +E   + I  E +  +L     + +++++ +K++ EQ+ T   + ++   
Sbjct: 573  K---KLEIKKEEYQNQHILYERVYEKLN----ITEQELSNIKNETEQIQTSLFSQINDFK 625

Query: 1219 ELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSS 1278
             L   +    +Q    I EL+  +  + +   Q     LR + S    K  QL+    S+
Sbjct: 626  ILNMKLEKENEQMKISI-ELFNDYKKESKEQIQ----SLRDENSKVNEKLVQLIQQNNSN 680

Query: 1279 TQEETNKIVTME-QVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEI---EDEKVAF 1334
            TQE+++ I  ++ ++ + Q +L+DK + +  L+E+  D     E+ + +I   E++    
Sbjct: 681  TQEKSSAISQLQIELKNYQIQLEDKVQKIEKLKEEVQDFKINEEVRKRQIQSLEEQSTDL 740

Query: 1335 XXXXXXXXXXXXXXXXDLRTENQSY---KQMQEQSILNINEENAQLKKSSXXXXXXXXXX 1391
                            DL    Q +   KQ  +++ + I  ++ +L++++          
Sbjct: 741  KQTIRQKDEQINNAQHDLEVYKQRFQICKQKLKEAFIQI-LDSIRLEQANKQLLLKLFEE 799

Query: 1392 XXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDL 1451
              ++    + +  L    E     I   T      L    +E  N+ +Q+ + +++I + 
Sbjct: 800  SLKIQFTRS-ICSLKDNYEDSILAIQMYTQGVLSDLKATQNEKSNLVEQIKQLKQQITEQ 858

Query: 1452 TYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKA 1511
            T +  +       +  E+ N  +  +K +++ +  + +E++    ++ SL  ++ + N+ 
Sbjct: 859  TKQNTAR------QKQESENMQQIQEKSNQLSK-NMKQEISELKKKNNSLLLEIQKSNEK 911

Query: 1512 LEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQ 1571
            + E      + ++  +  +  I +L +EI ++Q      + KI    S  S + Q   E+
Sbjct: 912  IIEYQLDQKKTKSEKDRMQETIDSLCEEIKHIQQDNNEKTEKINHWRSQESMSNQLEMER 971

Query: 1572 LDNTMNKEL 1580
            L     +EL
Sbjct: 972  LQKLCQQEL 980



 Score = 52.4 bits (120), Expect = 1e-04
 Identities = 130/693 (18%), Positives = 298/693 (43%), Gaps = 80/693 (11%)

Query: 153 EKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXE 212
           E +++ S+L++++  ++  +  L++K   K Q+++ K K                     
Sbjct: 293 ELESSQSILKLQLNEVQEKLKQLKKKHKHKKQLLKNKIKEYEIKLQEMEQEAMILTEQHR 352

Query: 213 DTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHS 272
           + K+ +T+  +         KD  + LL+  +  D+  ++L+  N  LE  + ++  +  
Sbjct: 353 NDKRNLTEQIQIT-------KDHYEYLLQQ-QQTDMA-NTLQNMNANLEEQKIKLRQD-- 401

Query: 273 KLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLE 332
            L ++ E+                 Q I+   + + EI++K   ++ +     K+I+   
Sbjct: 402 -LTEQFEKQSKANKQQYD-------QEIQKLKKREYEIQKKFDEQMHDFVIQNKQIQNNF 453

Query: 333 HLN---CQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQL 389
             N     ++  N++L+ +LA++ TE++   +        ++ K+      ++ +   QL
Sbjct: 454 FQNNDFALVKIENEKLKQELASVKTENQFALNQQNYTVNNLTEKNDA-LEEQIVNLKKQL 512

Query: 390 SSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLI 449
             + +  +  KK  ++     E + Q  N    DK+  ++EK             ++ + 
Sbjct: 513 GKQEIEYEKMKKQFESLKIDSETLSQRFNILQRDKDQAVNEKRQIQKNFDLLEKERNDIQ 572

Query: 450 AQLQLEHQQHMEGPSLIH-----VGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDL-IE 503
            +L+++ +++     L       +    ++++ I    EQ++  L  +I D  + ++ +E
Sbjct: 573 KKLEIKKEEYQNQHILYERVYEKLNITEQELSNIKNETEQIQTSLFSQINDFKILNMKLE 632

Query: 504 K---------------LKSAEEQITQLNDEIDAANKNMIKV----KSNHKLK---LKQMQ 541
           K                K ++EQI  L DE    N+ ++++     SN + K   + Q+Q
Sbjct: 633 KENEQMKISIELFNDYKKESKEQIQSLRDENSKVNEKLVQLIQQNNSNTQEKSSAISQLQ 692

Query: 542 KTIDNFS-KVSDSNKEIVRLTEELHHL-------SQKVAELEEEKGNLQLHLVDYD---S 590
             + N+  ++ D  ++I +L EE+           +++  LEE+  +L+  +   D   +
Sbjct: 693 IELKNYQIQLEDKVQKIEKLKEEVQDFKINEEVRKRQIQSLEEQSTDLKQTIRQKDEQIN 752

Query: 591 GRMIESDVYKKMIEMENLAETRLKA--ISLLESQKFDLVQELHILQQKYDEVEDKLADIS 648
               + +VYK+  +   + + +LK   I +L+S + +   +  +L+   + ++ +     
Sbjct: 753 NAQHDLEVYKQRFQ---ICKQKLKEAFIQILDSIRLEQANKQLLLKLFEESLKIQFTRSI 809

Query: 649 QLQSDQVCSEIKSVHLEEQ--IDALSASKKELALVIENLKLDKEQL-YGTIKDLENDKED 705
               D     I ++ +  Q  +  L A++ E + ++E +K  K+Q+   T ++    K++
Sbjct: 810 CSLKDNYEDSILAIQMYTQGVLSDLKATQNEKSNLVEQIKQLKQQITEQTKQNTARQKQE 869

Query: 706 IMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIE 765
             N  Q  IQE    +++L K   ++ISEL  K N+    +IQ     + KI E  L  +
Sbjct: 870 SENMQQ--IQEK---SNQLSKNMKQEISELKKK-NNSLLLEIQKS---NEKIIEYQLDQK 920

Query: 766 NIESELSKYKSRICRLEESIA-VMEDRRYSLER 797
             +SE  + +  I  L E I  + +D     E+
Sbjct: 921 KTKSEKDRMQETIDSLCEEIKHIQQDNNEKTEK 953


>UniRef50_UPI00006CC401 Cluster: hypothetical protein TTHERM_00133600;
            n=1; Tetrahymena thermophila SB210|Rep: hypothetical
            protein TTHERM_00133600 - Tetrahymena thermophila SB210
          Length = 1066

 Score =  124 bits (300), Expect = 2e-26
 Identities = 221/1143 (19%), Positives = 497/1143 (43%), Gaps = 114/1143 (9%)

Query: 475  VNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHK 534
            +N + K   QL +E  D   ++ V  L EK+ S E    QL ++     +  ++ +    
Sbjct: 20   LNSLTKSYNQLVKEKKDI--EIFVDTLREKVHSLEST-KQLYEQA----QQQLQTQKQSI 72

Query: 535  LKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMI 594
              L++ Q+ I   ++ ++ + +++++ +E +++ Q++ +++     L + ++D       
Sbjct: 73   QDLQKKQEAI--LAQKNEQDNKLIKVMKEKYNIQQELEKIKSSNEELSVTMIDEMEEMKK 130

Query: 595  ESDV-YKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSD 653
            + ++ +++  +++  A TR + + L +  +  L+++    Q +Y+E+ + L   +Q  S 
Sbjct: 131  KMNITFQEQSKIQQEA-TRQQILQLQQLSQQKLIEK----QMEYEEICNLLEKTNQELSY 185

Query: 654  Q--VCSEI--KSVHLEEQIDALSASKKELALVIENLK--LD--KEQLYGTIKDLENDKED 705
            Q  +C E+  K  +  E+I  LS    E    +E LK  LD  +E+    +      K++
Sbjct: 186  QQEMCKELEKKLEYSAEKIKELSNKLAEEKANVEALKKQLDEYREKYQKNLASQNQLKDE 245

Query: 706  IMN---KLQNYIQENMDLTDKLEKMSAEKIS--ELLAKINHEEQSKIQTQFGIDAKIQER 760
            ++N   K++    +   +TD+ + +S E  +    L+K+  E ++ ++ Q  +  +  E 
Sbjct: 246  LLNAQAKIKQLTTQLQQITDQQQLISGESSNYRSQLSKMEEEHRNLVEIQKFLSNENSEL 305

Query: 761  DLYIENIESELSKYKSRICRLEESIAVMED--RRYSLERKADQLGSYLQEKQKAYSEYTI 818
                 N + ++ + +++    +++I   +    + +LE+  D +      + K  S+   
Sbjct: 306  SNQSLNFKKQIEQLQNQQQEFKKAIESKDQAIEKLNLEKSQDLVKLETNYRSKIDSQMK- 364

Query: 819  QEDELVNRL-AVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYN 877
              D+L NRL  V M++ + ++K L   E+  ++L ++ Q L  E Q+ ++     Q++ N
Sbjct: 365  DIDQLTNRLNEVEMNYAKTLDK-LESSENTCRDLLQQIQNLQNELQSQKMIA---QENIN 420

Query: 878  ALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIE 937
             L +K     L E E      Q +  E NL  I+ + Q    Q    I+DL  E N  ++
Sbjct: 421  QLTQK-----LKEKEEKLAAVQ-KKYEQNLFEISQKEQ----QNNSYIQDLNKEVNN-LK 469

Query: 938  SAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQ 997
            + +  K   NE  +   + +  LE +L   K +++ L    ++  K  +E+ +  +QK+Q
Sbjct: 470  NIVTTKSRENEILQNQNQSIVVLEEKL---KISLQQLQQGAQKEEKYRIEIEEIAMQKEQ 526

Query: 998  TQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKL 1057
             +      +  N IN+++  LKQ  EEI +L  KI   +  Y   + + + K     +++
Sbjct: 527  YEK--LMHETTNRINQMSMQLKQCKEEISSLETKIEQDRKQYNVNLEEEKQKNEFANSQI 584

Query: 1058 ENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISST 1117
            + ++   Q++ +++L+++      Q  +++ ++Q++  K+ ++   MN    E     S 
Sbjct: 585  QELQFLCQKLKEEILENENVLSYTQQQLQQTEEQLQSAKD-QINI-MNQAMFERESYHSE 642

Query: 1118 IEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQ 1177
            +     ++N               LK+ E+E ++   + LQ  + ++  +     ++   
Sbjct: 643  VLNQQQNSN----------LELNTLKL-EKENYLNLVTELQTTNQQIKQDNSYLKSENDN 691

Query: 1178 LETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAE 1237
            L+    EL  +   NQE + Q    L+Q    N+NL      L+      +D       E
Sbjct: 692  LKKQFEELLQN---NQENLYQKDELLQQ----NENLSQQYKVLKQENHLILDNIQQIKQE 744

Query: 1238 LWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQN 1297
            L  ++  Q + D +   +++ +  S F   +  L   V    ++E   + T  Q + +QN
Sbjct: 745  LESKNKIQSD-DLRNANNQVNIAFSTFSQLFSHLALVVGQQVRDE-QLLDTFNQSSQIQN 802

Query: 1298 KLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQ 1357
             L        NL   +   +N       E   + ++                  L+ +  
Sbjct: 803  TLDQ-----LNLSSNFESKLN----FMKESMTQFLSTIKNMSDERLQNNQVSLQLKQQVA 853

Query: 1358 SYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIY 1417
              +Q+ +  +     E  QL+               ++N   AK+ +  +Q  +  S   
Sbjct: 854  QLQQINQNQLEQSQSERQQLQSQ----IQELEQSNQQLNQEIAKLKQQANQC-ISPSNQN 908

Query: 1418 QKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQ 1477
             K + Y +   Q  ++++  +  L++ +++++DL Y+ E      ++K ++  N     Q
Sbjct: 909  SKDNFYNMNYEQLENDYKISQSILLDQKQQLKDLKYDLEQ-----KIKKYQEENQVFAQQ 963

Query: 1478 KESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLN 1537
             +   ++V L+E       +  SL+K+  E    L       N+    ++ QE       
Sbjct: 964  NKELQDKVSLLE------AQKTSLSKEYGEQQNCL-------NDCFDKIQYQE------- 1003

Query: 1538 DEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDLAMYM-L 1596
             EI NLQ ++  S  +         + +   +E+  N MN E++++  ++  ++A +  L
Sbjct: 1004 QEIQNLQQLLEESDFENVLLKKIQQNNELNVEEESRNKMNSEIIESAKQSISNIARHFNL 1063

Query: 1597 HQR 1599
            +Q+
Sbjct: 1064 NQK 1066



 Score =  113 bits (271), Expect = 5e-23
 Identities = 171/870 (19%), Positives = 373/870 (42%), Gaps = 58/870 (6%)

Query: 474  DVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNH 533
            +  EI  + E+  QEL+   +    K+L +KL+ + E+I +L++++     N+  +K   
Sbjct: 168  EYEEICNLLEKTNQELS--YQQEMCKELEKKLEYSAEKIKELSNKLAEEKANVEALKKQL 225

Query: 534  KLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRM 593
                ++ QK + + +++ D   E++    ++  L+ ++ ++ +++  +     +Y S   
Sbjct: 226  DEYREKYQKNLASQNQLKD---ELLNAQAKIKQLTTQLQQITDQQQLISGESSNYRSQLS 282

Query: 594  IESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDE-VEDKLADISQLQS 652
               + ++ ++E++         +S         +++L   QQ++ + +E K   I +L  
Sbjct: 283  KMEEEHRNLVEIQKFLSNENSELSNQSLNFKKQIEQLQNQQQEFKKAIESKDQAIEKLNL 342

Query: 653  DQVCSEIK-SVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNK-- 709
            ++    +K   +   +ID+      +L   +  ++++  +    ++  EN   D++ +  
Sbjct: 343  EKSQDLVKLETNYRSKIDSQMKDIDQLTNRLNEVEMNYAKTLDKLESSENTCRDLLQQIQ 402

Query: 710  -LQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIE 768
             LQN +Q    +  +      +K+ E   K+   ++   Q  F I  K Q+ + YI+++ 
Sbjct: 403  NLQNELQSQKMIAQENINQLTQKLKEKEEKLAAVQKKYEQNLFEISQKEQQNNSYIQDLN 462

Query: 769  SELSKYKSRICRLEESIAVMEDRRYS---LERKAD------QLGSYLQEKQKA-YSEYTI 818
             E++  K+ +        +++++  S   LE K        Q G+  +EK +    E  +
Sbjct: 463  KEVNNLKNIVTTKSRENEILQNQNQSIVVLEEKLKISLQQLQQGAQKEEKYRIEIEEIAM 522

Query: 819  QED-------ELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSD 871
            Q++       E  NR+  +    +  ++++  +E + ++ +K+  + LEE +      + 
Sbjct: 523  QKEQYEKLMHETTNRINQMSMQLKQCKEEISSLETKIEQDRKQYNVNLEEEKQKNEFANS 582

Query: 872  MQQHYNALVEKANRTDLAESESTKY-QTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEI 930
              Q    L +K     L       Y Q QL+  E  L+    +   ++ Q   E E    
Sbjct: 583  QIQELQFLCQKLKEEILENENVLSYTQQQLQQTEEQLQS-AKDQINIMNQAMFERESYHS 641

Query: 931  EFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELID 990
            E   Q +++  +   L  + E  +  VT+L+   Q+ K +   L    + L K   EL+ 
Sbjct: 642  EVLNQQQNSNLELNTLKLEKENYLNLVTELQTTNQQIKQDNSYLKSENDNLKKQFEELLQ 701

Query: 991  KHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVS-DYESK 1049
             + Q+   Q  +  +Q  N +++   +LKQ++  I+   Q+I     S   + S D  + 
Sbjct: 702  NN-QENLYQKDELLQQNEN-LSQQYKVLKQENHLILDNIQQIKQELESKNKIQSDDLRNA 759

Query: 1050 LAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKE-LKETKLT--FE--M 1104
              Q         +    ++  L+  +Q  +E  +    Q  QI+  L +  L+  FE  +
Sbjct: 760  NNQVNIAFSTFSQLFSHLA--LVVGQQVRDEQLLDTFNQSSQIQNTLDQLNLSSNFESKL 817

Query: 1105 NIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKL 1164
            N  K       STI+ MSD+                 + +Q +++  Q + + Q Q  + 
Sbjct: 818  NFMKESMTQFLSTIKNMSDE-----------RLQNNQVSLQLKQQVAQLQQINQNQLEQS 866

Query: 1165 NTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQL---NTENDNLLSTVAELR 1221
             +E Q+  ++I +LE  N +L       ++Q NQ  S   Q    N  N N      + +
Sbjct: 867  QSERQQLQSQIQELEQSNQQLNQEIAKLKQQANQCISPSNQNSKDNFYNMNYEQLENDYK 926

Query: 1222 SSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQE 1281
             S S  +DQ+  ++ +L K  L Q+   +Q+       Q    + K   LL++ ++S  +
Sbjct: 927  ISQSILLDQKQ-QLKDL-KYDLEQKIKKYQEENQVFAQQNKELQDKV-SLLEAQKTSLSK 983

Query: 1282 ETNKIVTMEQVTSLQNKLQDKEEHLRNLQE 1311
            E  +      +    +K+Q +E+ ++NLQ+
Sbjct: 984  EYGE--QQNCLNDCFDKIQYQEQEIQNLQQ 1011



 Score =   99 bits (238), Expect = 5e-19
 Identities = 143/745 (19%), Positives = 323/745 (43%), Gaps = 57/745 (7%)

Query: 860  EENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIV 919
            E+ + +Q  L+ + + YN LV++  + D+     T  + ++  LES  K++  + Q  + 
Sbjct: 11   EDIKAVQNQLNSLTKSYNQLVKE--KKDIEIFVDT-LREKVHSLEST-KQLYEQAQQQLQ 66

Query: 920  QKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMN-V 978
             +K+ I+DL+     + E+ +  K   + K  K ++    ++ +L++ K++ E L++  +
Sbjct: 67   TQKQSIQDLQ----KKQEAILAQKNEQDNKLIKVMKEKYNIQQELEKIKSSNEELSVTMI 122

Query: 979  EELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNA---LLKQKD-EEIIALNQKINN 1034
            +E+ +M  ++ +   Q+Q     + T Q I ++ +L+    + KQ + EEI  L +K N 
Sbjct: 123  DEMEEMKKKM-NITFQEQSKIQQEATRQQILQLQQLSQQKLIEKQMEYEEICNLLEKTNQ 181

Query: 1035 AQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKE 1094
                   M  + E KL     K++ +  ++      +   K+  +E +   ++      +
Sbjct: 182  ELSYQQEMCKELEKKLEYSAEKIKELSNKLAEEKANVEALKKQLDEYREKYQKNLASQNQ 241

Query: 1095 LKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQER 1154
            LK+  L  +  I +     +++ ++ ++D    +             ++ +E    ++ +
Sbjct: 242  LKDELLNAQAKIKQ-----LTTQLQQITDQQQLISGESSNYRSQLSKME-EEHRNLVEIQ 295

Query: 1155 SVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLL 1214
              L  ++++L+ +      +I QL+    E        ++ I      +E+LN E    L
Sbjct: 296  KFLSNENSELSNQSLNFKKQIEQLQNQQQEF-------KKAIESKDQAIEKLNLEKSQDL 348

Query: 1215 STVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDS 1274
                +L ++  S +D +  +I +L  + L + E ++ KT  +L     + E+    LL  
Sbjct: 349  ---VKLETNYRSKIDSQMKDIDQLTNR-LNEVEMNYAKTLDKLE----SSENTCRDLLQQ 400

Query: 1275 VQSSTQE-ETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVA 1333
            +Q+   E ++ K++  E +  L  KL++KEE L  +Q+KY    N  EI  S+ E +  +
Sbjct: 401  IQNLQNELQSQKMIAQENINQLTQKLKEKEEKLAAVQKKYEQ--NLFEI--SQKEQQNNS 456

Query: 1334 FXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEE---NAQLKKSSXXXXXXXXX 1390
            +                    EN+   Q Q QSI+ + E+   + Q  +           
Sbjct: 457  YIQDLNKEVNNLKNIVTTKSRENE-ILQNQNQSIVVLEEKLKISLQQLQQGAQKEEKYRI 515

Query: 1391 XXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQL---VEYEKR 1447
                +   + +  +L H+   + +++  +  +    ++    + E  R+Q    +E EK+
Sbjct: 516  EIEEIAMQKEQYEKLMHETTNRINQMSMQLKQCKEEISSLETKIEQDRKQYNVNLEEEKQ 575

Query: 1448 IEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAE 1507
              +    +  EL  L  K+ E     E ++ E+ +   +  ++L     +  S   Q+  
Sbjct: 576  KNEFANSQIQELQFLCQKLKE-----EILENENVLSYTQ--QQLQQTEEQLQSAKDQINI 628

Query: 1508 LNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMV---RASSSKIQKHVSFASDT 1564
            +N+A+ E  +  +E+    +N  +E+ TL  E  N  N+V   + ++ +I++  S+    
Sbjct: 629  MNQAMFERESYHSEVLNQQQNSNLELNTLKLEKENYLNLVTELQTTNQQIKQDNSYLKSE 688

Query: 1565 KQGRDEQLDNTMNKELLDAVPRAEL 1589
                 +Q +  +     +   + EL
Sbjct: 689  NDNLKKQFEELLQNNQENLYQKDEL 713



 Score = 62.9 bits (146), Expect = 7e-08
 Identities = 125/692 (18%), Positives = 268/692 (38%), Gaps = 54/692 (7%)

Query: 92   ESLANTLKQKEILMEKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTI 151
            + L N L + E+   K     E S+ +   +++                  ++  L+  +
Sbjct: 367  DQLTNRLNEVEMNYAKTLDKLESSENTCRDLLQQIQNLQNELQSQKMIAQENINQLTQKL 426

Query: 152  KEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXX 211
            KEK+  L+ +Q K    E  + ++ +K  + +  I+  NK                    
Sbjct: 427  KEKEEKLAAVQKKY---EQNLFEISQKEQQNNSYIQDLNKEVNNLKNIVTTKSRE----- 478

Query: 212  EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKD---VRISSLEEANKLLEAARFEIS 268
                + +    ++ + +E + K   Q+L +  + ++   + I  +    +  E    E +
Sbjct: 479  ---NEILQNQNQSIVVLEEKLKISLQQLQQGAQKEEKYRIEIEEIAMQKEQYEKLMHETT 535

Query: 269  LEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKI 328
               ++++ +L+Q                KQ    + EE+ +  E  + +I  +  L +K+
Sbjct: 536  NRINQMSMQLKQCKEEISSLETKIEQDRKQ-YNVNLEEEKQKNEFANSQIQELQFLCQKL 594

Query: 329  --ELLEHLNC------QIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRN--- 377
              E+LE+ N       Q++QT ++L++    +   ++A+       S +++++   N   
Sbjct: 595  KEEILENENVLSYTQQQLQQTEEQLQSAKDQINIMNQAMFERESYHSEVLNQQQNSNLEL 654

Query: 378  -TASKMKSPWSQLSSE--TLNQDTD------KKINKNEIAKLEMVIQSLNKDLVDKEYVI 428
             T    K  +  L +E  T NQ         K  N N   + E ++Q+  ++L  K+ ++
Sbjct: 655  NTLKLEKENYLNLVTELQTTNQQIKQDNSYLKSENDNLKKQFEELLQNNQENLYQKDELL 714

Query: 429  SEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQE 488
             + +               ++  +Q + +Q +E  + I         N++        Q 
Sbjct: 715  QQNENLSQQYKVLKQENHLILDNIQ-QIKQELESKNKIQSDDLRNANNQVNIAFSTFSQL 773

Query: 489  LNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNF- 547
             +     V  +   E+L     Q +Q+ + +D  N     + SN + KL  M++++  F 
Sbjct: 774  FSHLALVVGQQVRDEQLLDTFNQSSQIQNTLDQLN-----LSSNFESKLNFMKESMTQFL 828

Query: 548  SKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRM------IESDVYKK 601
            S + + + E ++  +    L Q+VA+L++   N QL     +  ++      +E    + 
Sbjct: 829  STIKNMSDERLQNNQVSLQLKQQVAQLQQINQN-QLEQSQSERQQLQSQIQELEQSNQQL 887

Query: 602  MIEMENLAETRLKAISLLESQKFDLVQELHI--LQQKYDEVEDKLADISQLQSD-QVCSE 658
              E+  L +   + IS       D    ++   L+  Y   +  L D  Q   D +   E
Sbjct: 888  NQEIAKLKQQANQCISPSNQNSKDNFYNMNYEQLENDYKISQSILLDQKQQLKDLKYDLE 947

Query: 659  IKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENM 718
             K    +E+    +   KEL   +  L+  K  L     + +N   D  +K+Q   QE  
Sbjct: 948  QKIKKYQEENQVFAQQNKELQDKVSLLEAQKTSLSKEYGEQQNCLNDCFDKIQYQEQEIQ 1007

Query: 719  DLTDKLEKMSAEKISELLAKINHEEQSKIQTQ 750
            +L   LE+   E +  LL KI    +  ++ +
Sbjct: 1008 NLQQLLEESDFENV--LLKKIQQNNELNVEEE 1037


>UniRef50_UPI00006CAB41 Cluster: hypothetical protein TTHERM_00781040;
            n=1; Tetrahymena thermophila SB210|Rep: hypothetical
            protein TTHERM_00781040 - Tetrahymena thermophila SB210
          Length = 2198

 Score =  124 bits (300), Expect = 2e-26
 Identities = 272/1421 (19%), Positives = 596/1421 (41%), Gaps = 119/1421 (8%)

Query: 234  DEKQRLLKDIESKDVRISS-LEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXX 292
            +E++R L +I+    ++   LEE     E    ++ +E  +L +E +Q            
Sbjct: 451  EERERRLNEIQFVKEQVEKRLEETEIHYENVIHKLEIEIRRLQEENQQIRKEFLETKEQI 510

Query: 293  XX--LAKQSI-EPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKL 349
                + + ++ +   +E  +  E+   + A  TE  K++E  + L   I Q  +ELE ++
Sbjct: 511  DFERINQNTLNDRKLQESQDTWERRLQQCA--TEWQKEVEQRDQL---ISQKQRELEAQI 565

Query: 350  ATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAK 409
                   +      +K   L   K  R           +   + LN++  +K  K  +  
Sbjct: 566  RISQQNERKKIEIQQKYEALEKEKEKREEEFDSILQEQKRKIQILNEEVTQK--KVALKS 623

Query: 410  LEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVG 469
             ++ IQ  +++L  ++      +            + + +   + E+ Q       ++  
Sbjct: 624  AQISIQDAHEELAHRKNEGHVWNATEQQIKEKIALQKSRLQDCEEENAQLKRDKLALNEK 683

Query: 470  TNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKV 529
             +  + +++++ Q+++ +   D IK   VK  +E   + E Q      +I+     + +V
Sbjct: 684  ISILE-SKLSESQKEISKIQEDLIKQQQVK--LEVQLNQESQANNYRKQIETLRAQLHEV 740

Query: 530  KSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYD 589
            ++   +K+K+    + N S++++S + I  +  E    S K  ++ +E  NLQ  + ++ 
Sbjct: 741  QN--AIKIKESAYAVAN-SELNESRELIQEMKLEALRASHKQQQIADENNNLQSSVREWQ 797

Query: 590  ------SGRMIESDVYKKMIE--MENLAETRLKAISLLESQKFDLVQELHILQQKYDEVE 641
                    ++ ES   + +IE   +   +  L  I   E+Q+  + +EL  ++  ++  E
Sbjct: 798  RRAEQQQSQLEESRQIRSIIEEQQKKKVDELLMVIKQRETQQSCIEEELKAIKLSWENAE 857

Query: 642  DKLADISQ-LQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLE 700
              +  + + LQ  +   E+ +   + ++D+     +EL  +   L+ D  Q      +L 
Sbjct: 858  RAIQILEEKLQEKERAQELFADQAQRELDSQHDRIEELMRIQNKLENDLSQA-----NLF 912

Query: 701  NDKE-DIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQE 759
            NDK    +   QN IQ    +  +L+++  E+ +++   I + +Q  IQ Q    AK  E
Sbjct: 913  NDKSIKEIELFQNQIQSLTQMNHELQQLIEEQQAKV---IQNTDQKTIQAQQ--HAKRME 967

Query: 760  RDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQ 819
                + N E E    + ++  LE  +         L+R+ + +     + Q+   +   +
Sbjct: 968  LQQQLSNKEEECLNIQKQVIDLETQLEKQIRMFEDLQRENNLINLKYNDTQERLKQLQSE 1027

Query: 820  EDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNAL 879
             +E  N ++ + + +R +      +  ENK +Q   + +  E +  +   S++++  +A+
Sbjct: 1028 CEEYNNLISQIQEKERKISLANQNLVQENKRIQSVVEQITNELREQKQENSNLKECNDAI 1087

Query: 880  VEK-AN---RTDLAESESTKYQTQLRDLESNLKRITHE---HQTLIVQKKKEIEDLEIEF 932
             EK AN     D  + +  +Y      LE  ++ +  E   H T  +  K+E   +E   
Sbjct: 1088 CEKQANIQRENDRIKEQLEQYVNANAKLEEKVENLILENDSHSTENLALKQERIQIEYRL 1147

Query: 933  N-TQIESA-IRDKKVL----NEKYEKNI----EYVTQLEAQL--QEYKNNIEN--LNMNV 978
            + +Q +S  + ++ +L    NE+ + N     E++  ++ QL  Q++ + + N   N  V
Sbjct: 1148 SLSQNQSEKLNERSILLARENEEMKLNAIQREEFIAAIQQQLIDQQHDSVLRNNLQNQEV 1207

Query: 979  EELNKMNLELIDKHVQ-KQQTQSPDYT--EQYINEINKLNALLKQKDEEIIAL---NQKI 1032
            ++LNKM  +L D+    KQQ  S +    +Q IN++N   A L+   E+++ +   N+++
Sbjct: 1208 DKLNKMIKQLKDELTSLKQQMNSSNQEREQQLINQLNSSQAELQDFQEKLLIIRKENKQL 1267

Query: 1033 NNAQVSYMSMVSDYESKLAQFTTKLEN---------MEEEMQRVSKQLLDSKQHNEELQI 1083
            N+ +    + + +  SK  Q  T+LEN         ++EE +  S+Q+ D  Q  ++L+ 
Sbjct: 1268 NDIKGELQAQL-EVISKRNQ-ETQLENELLQKESTKLKEEKRNQSEQIRDLNQKCQKLEE 1325

Query: 1084 LVREQDDQIKELKETKLTF----EMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXX 1139
              +   D+++ LKE+        E  + + E  + S T +     A  +D          
Sbjct: 1326 REKNMIDELQVLKESFKNIHRDKESALLELETSLASGTAKEALKGAE-LDQVQSELKKVT 1384

Query: 1140 XXLKVQ-------------EEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELT 1186
              L+++             E EE  ++    +E+  KL  E      +I QL    TEL 
Sbjct: 1385 RRLELESTENKKKIQQLQTENEELKKQTDQEREKLRKLEYEAPNQIERINQLYARVTELN 1444

Query: 1187 GHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHL-AQ 1245
                  Q + + L S  EQL  E + L   + + + ++    +    +I E  K++L   
Sbjct: 1445 EQKSELQFKQDVLSSAHEQLKQEKELLQYQLDQAQKNVQMIQNSHKEQIEERDKKYLNLM 1504

Query: 1246 READFQKTE-HELRVQLSAFESKYEQLLDSVQSSTQE--ETN-KIVTM-EQVTSLQNKLQ 1300
            +  + +  E  EL++  S  E   + L  + +   QE  E N K++ + +Q+ +LQ +  
Sbjct: 1505 KNLNLKDQEIQELKLLNSQIEKDAQTLKINTELKIQENQELNQKVLNLNDQIQALQEQAA 1564

Query: 1301 DKEEHLRNLQE-KYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSY 1359
              +++++   E +Y      ++ + SE  D                       ++EN   
Sbjct: 1565 VTQQNIQQQNEVRYPSKSPSLKKI-SECIDSP-----NQEEYVQDPINKFASQKSENPK- 1617

Query: 1360 KQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDS-EIYQ 1418
            KQ+    I N     +  K S              V++ E ++ + + QLE + + +  Q
Sbjct: 1618 KQVSYSQISNPPSRKSS-KHSKNQINQDNNNDHYDVDNNENQLQDESEQLEFQGNLDNSQ 1676

Query: 1419 KTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKM-HENANHYETMQ 1477
            K     +     + +  NV ++ V Y K I +++  K SE     L    E+   +E ++
Sbjct: 1677 KEKSKRMERDDESQQQANVPKKSVSYSK-ISNISSRKSSENYQQSLNQGQEDDQEFEELE 1735

Query: 1478 KESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLN 1537
                 +  +    +  + TE  ++     + N   E E+   ++   +++N++++ +  N
Sbjct: 1736 YLGNQKNSQREMSMKAEKTEEYNIIPSQEDFN---EFEIDFNSQKNKSIDNRDLQNIASN 1792

Query: 1538 DEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNK 1578
              +  ++     S ++  K + F S  +  +++ ++   +K
Sbjct: 1793 KSLPKIK-----SQNQSSKQIPFESQVQSQQNQIIEELQDK 1828



 Score =  119 bits (287), Expect = 6e-25
 Identities = 222/1142 (19%), Positives = 514/1142 (45%), Gaps = 133/1142 (11%)

Query: 483  EQLKQELNDEIKDVNVKDLIEKLKSAEEQI---TQLNDEIDAANKNMIKVK---SNHKLK 536
            ++L +EL +E   + +K + E LKSA E +    +  DE+D+      K++   +  + K
Sbjct: 228  QKLFEELREENNQLKMKLVSEPLKSARESVEISRKYEDELDSIQIKYDKIEKQLAKTEKK 287

Query: 537  LKQMQKTIDN-FSKVSDSNKEIVRLTEELHHLS---QKVAELEEEKGNLQLHLVDYDSGR 592
             +  + TI   +  + D  KE+  L +EL +L    Q   +  +++G   +++++     
Sbjct: 288  CQDRKATIKKLYFLLEDKEKEVESLMQELENLRVNFQNKFQESDQRGQ-SIYILEKQIAE 346

Query: 593  MIESDVYKKMIEMENLAETRLKAI--SLLESQKFDLVQELHILQQKYDEVEDKLADISQL 650
            +   +  ++M+   N  +  L+ +  S+LE+Q+   +Q     ++ +     +   +   
Sbjct: 347  IQRQN--QEMVNSRNERKENLEELNRSILEAQQKYKIQ----CREDFPTTLMRWKSVRDF 400

Query: 651  QSDQVCSEIKSVHLEEQIDALSASKKELALVIE-NLKLDKEQLYGTIKDLE--NDKEDIM 707
             +D++  +I S+  EE +D     + EL   +E NL L+ E+L   +  L+   ++E  +
Sbjct: 401  FTDRL--KILSMQKEEAVDEQEKLRDELQREVERNLTLE-ERLTNYLNQLKQMEERERRL 457

Query: 708  NKLQNYIQENMDLTDKLEKMSAEKI---SELLAKINHEEQSKIQTQFGIDAKIQERDLYI 764
            N++Q +++E ++   +  ++  E +    E+  +   EE  +I+ +F ++ K Q   +  
Sbjct: 458  NEIQ-FVKEQVEKRLEETEIHYENVIHKLEIEIRRLQEENQQIRKEF-LETKEQ---IDF 512

Query: 765  ENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELV 824
            E I       +    +L+ES    E R   L++ A +    ++++ +  S+   ++ EL 
Sbjct: 513  ERINQNTLNDR----KLQESQDTWERR---LQQCATEWQKEVEQRDQLISQ---KQRELE 562

Query: 825  NRLAVLMDHDR----VVEK-QLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNAL 879
             ++ +   ++R    + +K + LE E E +E ++ + IL E+ + +QI   ++ Q   AL
Sbjct: 563  AQIRISQQNERKKIEIQQKYEALEKEKEKRE-EEFDSILQEQKRKIQILNEEVTQKKVAL 621

Query: 880  VEKANRTDLAESESTKYQTQLRDLESNLKRITHEH-QTLIVQKKKEIEDLEIEFNTQIES 938
              K+ +  + ++     +   R  E ++   T +  +  I  +K  ++D E E N Q++ 
Sbjct: 622  --KSAQISIQDAHE---ELAHRKNEGHVWNATEQQIKEKIALQKSRLQDCE-EENAQLK- 674

Query: 939  AIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQT 998
              RDK  LNEK       ++ LE++L E +  I  +  ++ +  ++ LE +  + + Q  
Sbjct: 675  --RDKLALNEK-------ISILESKLSESQKEISKIQEDLIKQQQVKLE-VQLNQESQAN 724

Query: 999  QSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSM------VSDYESKLAQ 1052
                  E    +++++   +K K+      N ++N ++     M       S  + ++A 
Sbjct: 725  NYRKQIETLRAQLHEVQNAIKIKESAYAVANSELNESRELIQEMKLEALRASHKQQQIAD 784

Query: 1053 FTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGM 1112
                L++   E QR ++Q     + + +++ ++ EQ  Q K++ E  +  +    +T+  
Sbjct: 785  ENNNLQSSVREWQRRAEQQQSQLEESRQIRSIIEEQ--QKKKVDELLMVIKQR--ETQQS 840

Query: 1113 IISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSA-KLNTELQEC 1171
             I   ++ +     N +              +Q  EE +QE+   QE  A +   EL   
Sbjct: 841  CIEEELKAIKLSWENAERA------------IQILEEKLQEKERAQELFADQAQRELDSQ 888

Query: 1172 YTKIIQL----ETLNTELTGHDVVNQEQINQL---KSKLEQLNTENDNLLSTVAELRSSI 1224
            + +I +L      L  +L+  ++ N + I ++   +++++ L   N  L   + E ++ +
Sbjct: 889  HDRIEELMRIQNKLENDLSQANLFNDKSIKEIELFQNQIQSLTQMNHELQQLIEEQQAKV 948

Query: 1225 SSAVDQRGFEIAELWK-----QHLAQREAD---FQK----TEHELRVQLSAFE--SKYEQ 1270
                DQ+  +  +  K     Q L+ +E +    QK     E +L  Q+  FE   +   
Sbjct: 949  IQNTDQKTIQAQQHAKRMELQQQLSNKEEECLNIQKQVIDLETQLEKQIRMFEDLQRENN 1008

Query: 1271 LLDSVQSSTQEETNKIVT-MEQVTSLQNKLQDKEEHL----RNLQEKYADVINQIEILRS 1325
            L++   + TQE   ++ +  E+  +L +++Q+KE  +    +NL ++   + + +E + +
Sbjct: 1009 LINLKYNDTQERLKQLQSECEEYNNLISQIQEKERKISLANQNLVQENKRIQSVVEQITN 1068

Query: 1326 EIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXX 1385
            E+ ++K                   +++ EN   K+  EQ +      NA+L++      
Sbjct: 1069 ELREQKQE-NSNLKECNDAICEKQANIQRENDRIKEQLEQYV----NANAKLEEKVENLI 1123

Query: 1386 XXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYE 1445
                         + + +++ ++L L  ++  +K +E +I L + N+E +    Q  E+ 
Sbjct: 1124 LENDSHSTENLALKQERIQIEYRLSLSQNQ-SEKLNERSILLARENEEMKLNAIQREEFI 1182

Query: 1446 KRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESV-----S 1500
              I+    +++ +  +     ++  +    M K+ + E   L +++N    E        
Sbjct: 1183 AAIQQQLIDQQHDSVLRNNLQNQEVDKLNKMIKQLKDELTSLKQQMNSSNQEREQQLINQ 1242

Query: 1501 LNKQVAELNKALEE--EVAKTNEMQTALENQ---EIEIVTLNDEITNLQN-MVRASSSKI 1554
            LN   AEL    E+   + K N+    ++ +   ++E+++  ++ T L+N +++  S+K+
Sbjct: 1243 LNSSQAELQDFQEKLLIIRKENKQLNDIKGELQAQLEVISKRNQETQLENELLQKESTKL 1302

Query: 1555 QK 1556
            ++
Sbjct: 1303 KE 1304



 Score =  111 bits (268), Expect = 1e-22
 Identities = 174/955 (18%), Positives = 412/955 (43%), Gaps = 68/955 (7%)

Query: 677  ELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELL 736
            ++   +   ++D+E +  +++ LE + E+   +   ++Q+    + K   +  +K+ E L
Sbjct: 178  DILYALNLFEIDRENMEKSLRHLEQETENFATQTL-FMQQGS--STKGNDLGYQKLFEEL 234

Query: 737  AKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLE 796
             + N++ + K+ ++    A+  E        E EL   + +  ++E+ +A  E +    +
Sbjct: 235  REENNQLKMKLVSEPLKSAR--ESVEISRKYEDELDSIQIKYDKIEKQLAKTEKKCQDRK 292

Query: 797  RKADQLGSYLQEKQKAYSEYTIQEDEL-VNRLAVLMDHDR------VVEKQLLEIEHENK 849
                +L   L++K+K       + + L VN      + D+      ++EKQ+ EI+ +N+
Sbjct: 293  ATIKKLYFLLEDKEKEVESLMQELENLRVNFQNKFQESDQRGQSIYILEKQIAEIQRQNQ 352

Query: 850  ELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTK--YQTQLRDLESNL 907
            E+        E  + L  S+ + QQ Y     +   T L   +S +  +  +L+ L    
Sbjct: 353  EMVNSRNERKENLEELNRSILEAQQKYKIQCREDFPTTLMRWKSVRDFFTDRLKILSMQK 412

Query: 908  KRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEK--NIEYV-TQLEAQL 964
            +    E + L  + ++E+E   +    ++ + +   K + E+  +   I++V  Q+E +L
Sbjct: 413  EEAVDEQEKLRDELQREVE-RNLTLEERLTNYLNQLKQMEERERRLNEIQFVKEQVEKRL 471

Query: 965  QE----YKNNIENLNMNVEELNKMNLELIDKHVQ-KQQTQSPDYTEQYINE--------- 1010
            +E    Y+N I  L + +  L + N ++  + ++ K+Q       +  +N+         
Sbjct: 472  EETEIHYENVIHKLEIEIRRLQEENQQIRKEFLETKEQIDFERINQNTLNDRKLQESQDT 531

Query: 1011 -INKLNALLKQKDEEIIALNQKINNAQVSYMSMV---SDYESKLAQFTTKLENMEEEMQR 1066
               +L     +  +E+   +Q I+  Q    + +      E K  +   K E +E+E ++
Sbjct: 532  WERRLQQCATEWQKEVEQRDQLISQKQRELEAQIRISQQNERKKIEIQQKYEALEKEKEK 591

Query: 1067 VSKQLLDS--KQHNEELQILVREQDDQIKELKETKLTF-----EMNIPKTEGMIISSTIE 1119
              ++  DS  ++   ++QIL  E   +   LK  +++      E+   K EG + ++T +
Sbjct: 592  REEE-FDSILQEQKRKIQILNEEVTQKKVALKSAQISIQDAHEELAHRKNEGHVWNATEQ 650

Query: 1120 PMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKII--Q 1177
             + +                  LK +++    ++ S+L+ + ++   E+ +    +I  Q
Sbjct: 651  QIKEKIALQKSRLQDCEEENAQLK-RDKLALNEKISILESKLSESQKEISKIQEDLIKQQ 709

Query: 1178 LETLNTELTGHDVVN--QEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQ-RGFE 1234
               L  +L      N  ++QI  L+++L ++        S  A   S ++ + +  +  +
Sbjct: 710  QVKLEVQLNQESQANNYRKQIETLRAQLHEVQNAIKIKESAYAVANSELNESRELIQEMK 769

Query: 1235 IAELWKQHLAQREADFQKT-EHELRVQLSAFESKYEQLLDS--VQSSTQEETNKIVTMEQ 1291
            +  L   H  Q+ AD     +  +R      E +  QL +S  ++S  +E+  K V    
Sbjct: 770  LEALRASHKQQQIADENNNLQSSVREWQRRAEQQQSQLEESRQIRSIIEEQQKKKVDELL 829

Query: 1292 VTSLQNKLQDK--EEHLRNLQEKYADVINQIEILRSEIEDEKVA---FXXXXXXXXXXXX 1346
            +   Q + Q    EE L+ ++  + +    I+IL  ++++++ A   F            
Sbjct: 830  MVIKQRETQQSCIEEELKAIKLSWENAERAIQILEEKLQEKERAQELFADQAQRELDSQH 889

Query: 1347 XXXXDL-RTENQSYKQMQEQSILNIN--EENAQLKKSSXXXXXXXXXXXXRVNDAEAKVL 1403
                +L R +N+    + + ++ N    +E    +                + + +AKV+
Sbjct: 890  DRIEELMRIQNKLENDLSQANLFNDKSIKEIELFQNQIQSLTQMNHELQQLIEEQQAKVI 949

Query: 1404 ELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIED---LTYEKESELA 1460
            + T Q  ++ ++ + K  E    L+ + +E  N+++Q+++ E ++E    +  + + E  
Sbjct: 950  QNTDQKTIQ-AQQHAKRMELQQQLSNKEEECLNIQKQVIDLETQLEKQIRMFEDLQRENN 1008

Query: 1461 ILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAK-T 1519
            ++ LK ++     + +Q E E E   LI ++  K  +    N+ + + NK ++  V + T
Sbjct: 1009 LINLKYNDTQERLKQLQSECE-EYNNLISQIQEKERKISLANQNLVQENKRIQSVVEQIT 1067

Query: 1520 NEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDN 1574
            NE++   + +   +   ND I   Q  ++  + +I++ +    +     +E+++N
Sbjct: 1068 NELREQ-KQENSNLKECNDAICEKQANIQRENDRIKEQLEQYVNANAKLEEKVEN 1121



 Score =  108 bits (259), Expect = 1e-21
 Identities = 267/1474 (18%), Positives = 620/1474 (42%), Gaps = 131/1474 (8%)

Query: 213  DTKQQMTKMQENFIA-----MEAEWKDEKQ--RLLKDIESKDVRISSLEEANKLLEAARF 265
            +++++++K+QE+ I      +E +   E Q     K IE+   ++  ++ A K+ E+A  
Sbjct: 693  ESQKEISKIQEDLIKQQQVKLEVQLNQESQANNYRKQIETLRAQLHEVQNAIKIKESAYA 752

Query: 266  EISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQS--IEPSCEEKTEIEEKGSLEIANMTE 323
              + E ++  + +++              +A ++  ++ S  E     E+   ++    +
Sbjct: 753  VANSELNESRELIQEMKLEALRASHKQQQIADENNNLQSSVREWQRRAEQQQSQLEESRQ 812

Query: 324  LTKKIELLEHLNC-QIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKM 382
            +   IE  +     ++    K+ E + + +  E KA+    +     I     +    + 
Sbjct: 813  IRSIIEEQQKKKVDELLMVIKQRETQQSCIEEELKAIKLSWENAERAIQILEEK---LQE 869

Query: 383  KSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXX 442
            K    +L ++   ++ D + ++  I +L  +   L  DL  +  + ++K           
Sbjct: 870  KERAQELFADQAQRELDSQHDR--IEELMRIQNKLENDL-SQANLFNDKSIKEIELFQNQ 926

Query: 443  XGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLI 502
                T +     +  +  +   + +    T    + AK  E  +Q  N E + +N++  +
Sbjct: 927  IQSLTQMNHELQQLIEEQQAKVIQNTDQKTIQAQQHAKRMELQQQLSNKEEECLNIQKQV 986

Query: 503  EKLKSAEEQITQLNDEIDAANKNMIKVKSNH-KLKLKQMQKTIDNFS-----------KV 550
              L++  E+  ++ +++   N N+I +K N  + +LKQ+Q   + ++           K+
Sbjct: 987  IDLETQLEKQIRMFEDLQREN-NLINLKYNDTQERLKQLQSECEEYNNLISQIQEKERKI 1045

Query: 551  SDSNKEIV----RLTEELHHLSQKVAELEEEKGNLQL---HLVDYDSGRMIESDVYKKMI 603
            S +N+ +V    R+   +  ++ ++ E ++E  NL+     + +  +    E+D  K+ +
Sbjct: 1046 SLANQNLVQENKRIQSVVEQITNELREQKQENSNLKECNDAICEKQANIQRENDRIKEQL 1105

Query: 604  EMENLAETRL--KAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCS-EIK 660
            E    A  +L  K  +L+        + L + Q++  ++E +L+ +SQ QS+++    I 
Sbjct: 1106 EQYVNANAKLEEKVENLILENDSHSTENLALKQERI-QIEYRLS-LSQNQSEKLNERSIL 1163

Query: 661  SVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENM-D 719
                 E++   +  ++E    I+   +D++       +L+N + D +NK+   +++ +  
Sbjct: 1164 LARENEEMKLNAIQREEFIAAIQQQLIDQQHDSVLRNNLQNQEVDKLNKMIKQLKDELTS 1223

Query: 720  LTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELS------K 773
            L  ++   + E+  +L+ ++N   Q+++Q        I++ +  + +I+ EL        
Sbjct: 1224 LKQQMNSSNQEREQQLINQLN-SSQAELQDFQEKLLIIRKENKQLNDIKGELQAQLEVIS 1282

Query: 774  YKSRICRLEESIAVMEDRRYSLERK--ADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLM 831
             +++  +LE  +   E  +   E++  ++Q+    Q+ QK         DEL        
Sbjct: 1283 KRNQETQLENELLQKESTKLKEEKRNQSEQIRDLNQKCQKLEEREKNMIDELQVLKESFK 1342

Query: 832  DHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDL--- 888
            +  R  E  LLE+E        K  +   E   +Q  L  + +    L    N+  +   
Sbjct: 1343 NIHRDKESALLELETSLASGTAKEALKGAELDQVQSELKKVTRRLE-LESTENKKKIQQL 1401

Query: 889  -AESESTKYQT-----QLRDLE----SNLKRIT--HEHQTLIVQKKKEIEDLEIEFNTQI 936
              E+E  K QT     +LR LE    + ++RI   +   T + ++K E++  +   ++  
Sbjct: 1402 QTENEELKKQTDQEREKLRKLEYEAPNQIERINQLYARVTELNEQKSELQFKQDVLSSAH 1461

Query: 937  ESAIRDKKVLN---EKYEKNIEYV-----TQLEAQLQEYKNNIENLNMNVEELNKMNLEL 988
            E   ++K++L    ++ +KN++ +      Q+E + ++Y N ++NLN+  +E+ +  L+L
Sbjct: 1462 EQLKQEKELLQYQLDQAQKNVQMIQNSHKEQIEERDKKYLNLMKNLNLKDQEIQE--LKL 1519

Query: 989  IDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQK--INNAQVSYMSMVSDY 1046
            ++  ++K        TE  I E  +LN  +   +++I AL ++  +    +   + V  Y
Sbjct: 1520 LNSQIEKDAQTLKINTELKIQENQELNQKVLNLNDQIQALQEQAAVTQQNIQQQNEVR-Y 1578

Query: 1047 ESK---LAQFTTKLE--NMEEEMQRVSKQLLDSKQHNEELQILVRE--QDDQIKELKETK 1099
             SK   L + +  ++  N EE +Q    +    K  N + Q+   +       K  K +K
Sbjct: 1579 PSKSPSLKKISECIDSPNQEEYVQDPINKFASQKSENPKKQVSYSQISNPPSRKSSKHSK 1638

Query: 1100 LTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQE 1159
                 +    +   + +    + D++  ++             K  E ++  Q+++ + +
Sbjct: 1639 NQINQD-NNNDHYDVDNNENQLQDESEQLEFQGNLDNSQKEKSKRMERDDESQQQANVPK 1697

Query: 1160 QSAKLNTELQECYTKIIQLETLNTELTGHDVVNQ-EQINQLKSKLEQLNTENDNL--LST 1216
            +S          Y+KI  + +  +       +NQ ++ +Q   +LE L  + ++   +S 
Sbjct: 1698 KSVS--------YSKISNISSRKSSENYQQSLNQGQEDDQEFEELEYLGNQKNSQREMSM 1749

Query: 1217 VAELRSS---ISSAVDQRGFEIAELWKQHLAQREADFQK-TEHELRVQLSAFESKYEQLL 1272
             AE       I S  D   FEI    +++ +    D Q    ++   ++ +     +Q+ 
Sbjct: 1750 KAEKTEEYNIIPSQEDFNEFEIDFNSQKNKSIDNRDLQNIASNKSLPKIKSQNQSSKQI- 1808

Query: 1273 DSVQSSTQEETNKIV--TMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDE 1330
               +S  Q + N+I+    +++  LQ +++   + + N Q +  ++ +QIE L+S I ++
Sbjct: 1809 -PFESQVQSQQNQIIEELQDKLNELQLEIETLSQQMLNYQSENQELNDQIEKLKS-INEK 1866

Query: 1331 KVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQ-------SILNINEENAQLKKSSXX 1383
                                 L+ + + +K   ++       +I N+  +    +  S  
Sbjct: 1867 MTTDNLDLTNQVNSHEIKEKKLQQQFEQFKNSSQENEKKLSKNIQNMERQIVDEQNKSNQ 1926

Query: 1384 XXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIY---QKTHEYTITLTQRNDEFENVRQQ 1440
                      ++N A+ ++LE   ++  +  EI     +  + + T+    D+ E+  + 
Sbjct: 1927 LKQQIQQLQQQINLAKDEILEQNERISAQQQEIVLGENQIDQQSQTILLLQDKIESQAEY 1986

Query: 1441 LVEYEKRI-EDLTY--EKESELAILRLKMHENAN-HYETMQK-ESEIE-RVKLIEELNVK 1494
            L   E+ + E   Y  + E+ L   R ++ E+ N   ET Q+ + E++ + + I +L   
Sbjct: 1987 LKHVEEELKEQKNYASQLENNLEKKRKQLEESDNLQIETEQRLKQELQLKYEYIAKLEST 2046

Query: 1495 ITESVSLN-KQVAELNKALEEEVAK-TNEMQTALENQEIEIVTLNDEITNLQNMVRASSS 1552
                  L   Q  +    L+ EV +   ++  A ++Q I    L  +I +LQ  +R  + 
Sbjct: 2047 YKNKAELTLAQSQQATAELQSEVNRLKQQLAEAKQDQNIN-EGLKRQIRDLQRQLREVNM 2105

Query: 1553 KIQK----HVSFASDTKQGRDEQLDNTMNKELLD 1582
            + +K       +  D    R  Q D  +  E+L+
Sbjct: 2106 EYEKLLIERQQYEDDMNLQRLSQQDLAIKFEVLE 2139



 Score = 99.1 bits (236), Expect = 9e-19
 Identities = 191/1106 (17%), Positives = 479/1106 (43%), Gaps = 78/1106 (7%)

Query: 212  EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271
            ++ +++++   +N +      +   +++  ++  +    S+L+E N  +   +  I  E+
Sbjct: 1039 QEKERKISLANQNLVQENKRIQSVVEQITNELREQKQENSNLKECNDAICEKQANIQREN 1098

Query: 272  SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCE------EKTEIEEKGSLEIANMTELT 325
             ++ ++LEQ              L  ++   S E      E+ +IE + SL      +L 
Sbjct: 1099 DRIKEQLEQYVNANAKLEEKVENLILENDSHSTENLALKQERIQIEYRLSLSQNQSEKLN 1158

Query: 326  KKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSP 385
            ++  LL   N +++    + E  +A +  + + +    ++   ++          K+   
Sbjct: 1159 ERSILLARENEEMKLNAIQREEFIAAI--QQQLI---DQQHDSVLRNNLQNQEVDKLNKM 1213

Query: 386  WSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGK 445
              QL  E  +    +++N +   + + +I  LN    + +    +              K
Sbjct: 1214 IKQLKDELTS--LKQQMNSSNQEREQQLINQLNSSQAELQDFQEKLLIIRKENKQLNDIK 1271

Query: 446  DTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNE-IAKVQEQLKQELNDEIKDVNVKDLIEK 504
              L AQL++  +++ E          T+  NE + K   +LK+E  ++ +   ++DL +K
Sbjct: 1272 GELQAQLEVISKRNQE----------TQLENELLQKESTKLKEEKRNQSE--QIRDLNQK 1319

Query: 505  LKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTI-DNFSKVSDSNKEIVRLTEE 563
             +  EE+   + DE+    ++   +  + +  L +++ ++    +K +    E+ ++  E
Sbjct: 1320 CQKLEEREKNMIDELQVLKESFKNIHRDKESALLELETSLASGTAKEALKGAELDQVQSE 1379

Query: 564  LHHLSQKV-AELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQ 622
            L  +++++  E  E K  +Q    + +  +       +K+ ++E  A  +++ I+ L ++
Sbjct: 1380 LKKVTRRLELESTENKKKIQQLQTENEELKKQTDQEREKLRKLEYEAPNQIERINQLYAR 1439

Query: 623  KFDLVQELHILQQKYD---EVEDKL---ADISQLQSDQVCSEIKSVHLEEQIDALSASKK 676
              +L ++   LQ K D      ++L    ++ Q Q DQ    ++ +    +       KK
Sbjct: 1440 VTELNEQKSELQFKQDVLSSAHEQLKQEKELLQYQLDQAQKNVQMIQNSHKEQIEERDKK 1499

Query: 677  ELALVIENLKL-DKE--QLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKL----EKMSA 729
             L L ++NL L D+E  +L      +E D + +    +  IQEN +L  K+    +++ A
Sbjct: 1500 YLNL-MKNLNLKDQEIQELKLLNSQIEKDAQTLKINTELKIQENQELNQKVLNLNDQIQA 1558

Query: 730  EKISELLAKINHEEQSKIQ--TQFGIDAKIQE------RDLYIENIESELSKYKSRICRL 781
             +    + + N ++Q++++  ++     KI E      ++ Y+++  ++ +  KS   + 
Sbjct: 1559 LQEQAAVTQQNIQQQNEVRYPSKSPSLKKISECIDSPNQEEYVQDPINKFASQKSENPKK 1618

Query: 782  EESIAVMED--RRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVL-----MDHD 834
            + S + + +   R S +   +Q+    Q+    + +    E++L +    L     +D+ 
Sbjct: 1619 QVSYSQISNPPSRKSSKHSKNQIN---QDNNNDHYDVDNNENQLQDESEQLEFQGNLDNS 1675

Query: 835  RVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESEST 894
            +  + + +E + E+++     +  +  ++   IS     ++Y   + +    D  E E  
Sbjct: 1676 QKEKSKRMERDDESQQQANVPKKSVSYSKISNISSRKSSENYQQSLNQGQEDD-QEFEEL 1734

Query: 895  KYQTQLRDLESNLK-RITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKN 953
            +Y    ++ +  +  +     +  I+  +++  + EI+FN+Q   +I ++ + N    K+
Sbjct: 1735 EYLGNQKNSQREMSMKAEKTEEYNIIPSQEDFNEFEIDFNSQKNKSIDNRDLQNIASNKS 1794

Query: 954  IEYV-TQLEAQLQ-EYKNNIEN-LNMNVEEL-NKMN-LELIDKHVQKQQTQSPDYTEQYI 1008
            +  + +Q ++  Q  +++ +++  N  +EEL +K+N L+L  + + +Q        ++  
Sbjct: 1795 LPKIKSQNQSSKQIPFESQVQSQQNQIIEELQDKLNELQLEIETLSQQMLNYQSENQELN 1854

Query: 1009 NEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVS 1068
            ++I KL ++ ++   + + L  ++N+ ++    +   +E          + + + +Q + 
Sbjct: 1855 DQIEKLKSINEKMTTDNLDLTNQVNSHEIKEKKLQQQFEQFKNSSQENEKKLSKNIQNME 1914

Query: 1069 KQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNV 1128
            +Q++D +  + +L+  +++   QI   K+  L     I   +  I+      +   +  +
Sbjct: 1915 RQIVDEQNKSNQLKQQIQQLQQQINLAKDEILEQNERISAQQQEIVLGE-NQIDQQSQTI 1973

Query: 1129 DXXXXXXXXXXXXLKVQEEEEFIQER--SVLQEQSAKLNTELQECYTKIIQLETLNTELT 1186
                         LK  EEE   Q+   S L+    K   +L+E  +  +Q+ET    L 
Sbjct: 1974 LLLQDKIESQAEYLKHVEEELKEQKNYASQLENNLEKKRKQLEE--SDNLQIET-EQRLK 2030

Query: 1187 GHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQR 1246
                +  E I +L+S  +    + +  L+   +  + + S V++   ++AE  KQ     
Sbjct: 2031 QELQLKYEYIAKLESTYK---NKAELTLAQSQQATAELQSEVNRLKQQLAEA-KQDQNIN 2086

Query: 1247 EADFQKTEHELRVQLSAFESKYEQLL 1272
            E   ++   +L+ QL     +YE+LL
Sbjct: 2087 EG-LKRQIRDLQRQLREVNMEYEKLL 2111



 Score = 98.3 bits (234), Expect = 2e-18
 Identities = 215/1131 (19%), Positives = 472/1131 (41%), Gaps = 113/1131 (9%)

Query: 499  KDLIEKLKSAEEQITQLNDE---IDAANKNMIKVKSNHKLKLKQ-MQKTIDNFSKVSDSN 554
            K + E  +  +E +   N+    ++  N+++++ +  +K++ ++    T+  +  V D  
Sbjct: 342  KQIAEIQRQNQEMVNSRNERKENLEELNRSILEAQQKYKIQCREDFPTTLMRWKSVRDF- 400

Query: 555  KEIVRLTEELHHLSQKVAELEEEKGNLQLHLV-DYDSGRMIESDV--YKKMIEMENLAET 611
                  T+ L  LS +  E  +E+  L+  L  + +    +E  +  Y   ++     E 
Sbjct: 401  -----FTDRLKILSMQKEEAVDEQEKLRDELQREVERNLTLEERLTNYLNQLKQMEERER 455

Query: 612  RLKAISLLESQKFDLVQELHILQQKYDEVEDKLA-DISQLQSDQVCSEIKSVHLEEQIDA 670
            RL  I  ++ Q    ++E  I    Y+ V  KL  +I +LQ +      + +  +EQID 
Sbjct: 456  RLNEIQFVKEQVEKRLEETEI---HYENVIHKLEIEIRRLQEENQQIRKEFLETKEQID- 511

Query: 671  LSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAE 730
                      + +N   D++        L+  ++    +LQ    E     ++ +++ ++
Sbjct: 512  -------FERINQNTLNDRK--------LQESQDTWERRLQQCATEWQKEVEQRDQLISQ 556

Query: 731  KISELLAKIN---HEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAV 787
            K  EL A+I      E+ KI+ Q   +A  +E++   E  +S L + K +I  L E +  
Sbjct: 557  KQRELEAQIRISQQNERKKIEIQQKYEALEKEKEKREEEFDSILQEQKRKIQILNEEVTQ 616

Query: 788  MEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHE 847
             +    S +         L  ++     +   E ++  ++A       + + +L + E E
Sbjct: 617  KKVALKSAQISIQDAHEELAHRKNEGHVWNATEQQIKEKIA-------LQKSRLQDCEEE 669

Query: 848  NKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNL 907
            N +L++    L E+   L+  LS+ Q+  + + E     DL + +  K + QL   ES  
Sbjct: 670  NAQLKRDKLALNEKISILESKLSESQKEISKIQE-----DLIKQQQVKLEVQLNQ-ESQA 723

Query: 908  KRITHEHQTLIVQKKKEIEDLEIEFNTQ--IESAIRDKKVLNEKYEKNIEYVTQLEAQLQ 965
                 + +TL  Q  +    ++I+ +      S + + + L ++ +      +  + Q+ 
Sbjct: 724  NNYRKQIETLRAQLHEVQNAIKIKESAYAVANSELNESRELIQEMKLEALRASHKQQQIA 783

Query: 966  EYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEI 1025
            +  NN+++   +V E  +   +   +  + +Q +S    EQ   ++++L  ++KQ++ + 
Sbjct: 784  DENNNLQS---SVREWQRRAEQQQSQLEESRQIRS-IIEEQQKKKVDELLMVIKQRETQQ 839

Query: 1026 IALNQKINNAQVSYMS---MVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQ 1082
              + +++   ++S+ +    +   E KL +     E   ++ QR     LDS QH + ++
Sbjct: 840  SCIEEELKAIKLSWENAERAIQILEEKLQEKERAQELFADQAQRE----LDS-QH-DRIE 893

Query: 1083 ILVREQDDQIKELKETKLTFEMNIPKTE---GMIISST----------IEPMSDDANNVD 1129
             L+R Q+    +L +  L  + +I + E     I S T           E  +    N D
Sbjct: 894  ELMRIQNKLENDLSQANLFNDKSIKEIELFQNQIQSLTQMNHELQQLIEEQQAKVIQNTD 953

Query: 1130 XXXXXXXXXXXXLKVQEEEEFIQERSV-LQEQSAKLNTELQECYTKIIQLETLNTELTGH 1188
                        +++Q++    +E  + +Q+Q   L T+L++       L+  N  +   
Sbjct: 954  QKTIQAQQHAKRMELQQQLSNKEEECLNIQKQVIDLETQLEKQIRMFEDLQRENNLINLK 1013

Query: 1189 DVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREA 1248
                QE++ QL+S+ E+ N    NL+S + E    IS A         +   Q   + ++
Sbjct: 1014 YNDTQERLKQLQSECEEYN----NLISQIQEKERKISLA--------NQNLVQENKRIQS 1061

Query: 1249 DFQKTEHELRVQLSAFESKYEQLLDSV---QSSTQEETNKI-VTMEQVTSLQNKLQDKEE 1304
              ++  +ELR Q     S  ++  D++   Q++ Q E ++I   +EQ  +   KL++K E
Sbjct: 1062 VVEQITNELREQKQE-NSNLKECNDAICEKQANIQRENDRIKEQLEQYVNANAKLEEKVE 1120

Query: 1305 HLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQ- 1363
            +L  + E  +     + + +  I+ E                        E      +Q 
Sbjct: 1121 NL--ILENDSHSTENLALKQERIQIEYRLSLSQNQSEKLNERSILLARENEEMKLNAIQR 1178

Query: 1364 EQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVL-ELTHQLELKDSEIYQKTHE 1422
            E+ I  I ++    +  S            ++N    ++  ELT   +  +S   ++  +
Sbjct: 1179 EEFIAAIQQQLIDQQHDSVLRNNLQNQEVDKLNKMIKQLKDELTSLKQQMNSSNQEREQQ 1238

Query: 1423 YTITLTQRNDEFENVRQQLV---EYEKRIEDLTYEKESELAILRLKMHENANHYETMQKE 1479
                L     E ++ +++L+   +  K++ D+  E +++L ++  +  E     E +QKE
Sbjct: 1239 LINQLNSSQAELQDFQEKLLIIRKENKQLNDIKGELQAQLEVISKRNQETQLENELLQKE 1298

Query: 1480 S------EIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTN-EMQTALENQEIE 1532
            S      +  + + I +LN K  +     K + +  + L+E     + + ++AL   E  
Sbjct: 1299 STKLKEEKRNQSEQIRDLNQKCQKLEEREKNMIDELQVLKESFKNIHRDKESALLELETS 1358

Query: 1533 IV--TLNDEITNLQ-NMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKEL 1580
            +   T  + +   + + V++   K+ + +   S   + + +QL  T N+EL
Sbjct: 1359 LASGTAKEALKGAELDQVQSELKKVTRRLELESTENKKKIQQL-QTENEEL 1408


>UniRef50_Q22CJ7 Cluster: Putative uncharacterized protein; n=1;
            Tetrahymena thermophila SB210|Rep: Putative
            uncharacterized protein - Tetrahymena thermophila SB210
          Length = 1640

 Score =  124 bits (300), Expect = 2e-26
 Identities = 211/1037 (20%), Positives = 444/1037 (42%), Gaps = 92/1037 (8%)

Query: 555  KEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLK 614
            +E+    +EL + + K++EL EEKG L   + D       E  V K +IE   L E   +
Sbjct: 582  RELEEQVKELVNENSKLSELLEEKGYLLQQIQD-------EQLVQKLLIENNELKEKLRQ 634

Query: 615  AISLLESQKFDLVQELHILQQKYDEV-EDKLADISQLQSDQVCSEIKSVHLEEQIDALSA 673
            A   +E+      + LH      +++  +K+ +I +L+ +++    +S   + ++D L  
Sbjct: 635  A--QMENDLSIQNRVLHTENTNLNKILSEKVKEIRELK-EKLQQNSQSQESQRKVDQLER 691

Query: 674  SKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNK---LQNYIQENMDLTDKLEKMSAE 730
            + K L    E+L    +Q    ++   +D  ++ NK   LQ+YIQE  +   + + +S E
Sbjct: 692  NIKLLIQENEHLSDVLKQRQSEVQKQRDDNLEMQNKVINLQSYIQELQEQQSRQQSISNE 751

Query: 731  KISEL----------LAKINHEEQSKIQTQFGIDAKIQERDLYI----ENIESELSKY-K 775
            K + L          LA+  HE Q K Q    I+ + +++   +    E +   +S+Y  
Sbjct: 752  KFNSLKSEYDKIQNKLAEKEHELQQKEQNAQKINREAEDQITKLVDENEKLNEIISQYIN 811

Query: 776  SRICRLEESIAVMEDR-RYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHD 834
            S    L  S+A+ ++  + ++ +  ++        Q    +Y   E+++ N +A   + +
Sbjct: 812  SSNTDLLNSMAINKNTSKLNIVKDDEEKLQMFDSLQNCNKDY---EEKIKNLIAQNKNLE 868

Query: 835  RVV---EKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAES 891
             V+   EK  +E+    + ++ + +++ ++N +LQ+ +  + +   A  E A++  L ES
Sbjct: 869  EVILDLEKDKIELAENLQFMEDRQKVIEKQNDDLQMEIEKLSKQETACTEIADKVKLLES 928

Query: 892  ESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYE 951
            ++     Q+  +   L + + E+Q ++ Q +      E     +IE   R  + L E  +
Sbjct: 929  QNQDLHLQIDQMNQGLTQKSEENQLIVQQNENNKNYFEQIIQEKIEQINRLSQQLQE--Q 986

Query: 952  KNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLE--LIDKHVQKQQTQSPDYTEQYIN 1009
             N     Q + Q+Q+     E+     +     N +  L  +  Q+    S D  ++ I 
Sbjct: 987  SNFIQALQQQQQIQQIHEREEDEQEEEKTKKAANKKQTLPSQRYQRDDQISEDEDQEQIQ 1046

Query: 1010 EINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYES---KLAQFTTKLENMEEEMQR 1066
            + N+ N  +K  D     LN+     + S   + +  +S   +L +F  +L+   + ++ 
Sbjct: 1047 QQNQENN-IKSADSTFNQLNEDNYFDKESEQLIETPLDSNTFELTKFQKELKEKNDIIKN 1105

Query: 1067 VSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDAN 1126
            + + L   K+   EL   V++Q   I +L+E K+    N    +G  I   +   S+D  
Sbjct: 1106 LCENLDFQKEQVSELNEKVQQQAIFIIDLQE-KIKKSQNEINQQGEKILELLSNASED-- 1162

Query: 1127 NVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQS-AKLNTELQECYTKIIQLETLNTEL 1185
                              Q ++E +Q++   ++ +  +    ++E   KII L+ L  EL
Sbjct: 1163 --QSISKSQRKSREIASQQNDQELLQQQLEYKDHAIQEYILVIRELDDKIINLQKLLKEL 1220

Query: 1186 TGH-DVVNQEQINQLKS-KLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHL 1243
                 + N   I +L+S  L   N  N+     + ++   I   V Q+  +     KQ  
Sbjct: 1221 KPDLQLDNSFYIERLESLNLLSPNISNNLKERKITQMEERILIQVQQQDNDEDNHQKQ-- 1278

Query: 1244 AQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKE 1303
             Q   + QK +  +  ++S F+ KY+Q ++ ++       N+    E++ SL N    + 
Sbjct: 1279 -QNLINPQKIQSLIDREISQFDQKYKQKMEELEKEMSVSINE--RDEKIVSLIN----EN 1331

Query: 1304 EHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQ 1363
            + L  L E+    + +++IL  +IE  K                   D +T     K++Q
Sbjct: 1332 QKLLQLNEQR---LIELKILNQQIEMRK--------------EQNIRDTKTIEDLQKKIQ 1374

Query: 1364 EQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEY 1423
                 NI +    LK S             + N +E  +++   + E ++S+        
Sbjct: 1375 MMLSKNIQQNKGILKNSQ----------HFQQNTSERSLIDSIREEESEESQDVDSQKNQ 1424

Query: 1424 TITLTQRNDEFENVRQQLVEYEKRIEDLTYEKES-ELAILRLKMHENANHYETMQKESEI 1482
                +Q + E + ++++L E  +++ D   E E+ +  +L  +  E     E  Q + E+
Sbjct: 1425 QQHASQ-SHEAKRLQRKLEEKRRQLSDAKQELENLKEKLLDFEEIEFRLTSENRQLQEEV 1483

Query: 1483 ERVKLIEELNVKITESVSLNK-QVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEIT 1541
             R+    + N ++ E +   K +  EL K  E   A+ +E+   L++ + +  + ++++ 
Sbjct: 1484 RRLSQHSDENNRLNEMLKTRKNEYTELKKRFEALRAERDELIQKLKDSQFQDGSPSNQLN 1543

Query: 1542 NLQNMVRASSSKIQKHV 1558
            N ++    +S ++ K +
Sbjct: 1544 NSKSF-NVNSFELYKEI 1559



 Score =  107 bits (258), Expect = 2e-21
 Identities = 213/1084 (19%), Positives = 483/1084 (44%), Gaps = 114/1084 (10%)

Query: 297  KQSIEPSCEEKTEIEEKGSL-EIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTE 355
            K+ +  + +    +EEKG L +     +L +K+ L+E+   + +    ++EN L+    +
Sbjct: 589  KELVNENSKLSELLEEKGYLLQQIQDEQLVQKL-LIENNELKEKLRQAQMENDLSI---Q 644

Query: 356  SKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQ 415
            ++ + + +   + ++S K       +++    +L   + +Q++ +K+++ E   ++++IQ
Sbjct: 645  NRVLHTENTNLNKILSEK-----VKEIRELKEKLQQNSQSQESQRKVDQLE-RNIKLLIQ 698

Query: 416  SLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDV 475
              N+ L D   V+ ++ +               +  LQ   Q+  E  S     +N E  
Sbjct: 699  E-NEHLSD---VLKQRQSEVQKQRDDNLEMQNKVINLQSYIQELQEQQSRQQSISN-EKF 753

Query: 476  NEIAKVQEQLKQELNDEIKDVNVKDL-IEKL-KSAEEQITQLNDEIDAANKNMIKVKSNH 533
            N +    ++++ +L ++  ++  K+   +K+ + AE+QIT+L DE +  N+ + +  ++ 
Sbjct: 754  NSLKSEYDKIQNKLAEKEHELQQKEQNAQKINREAEDQITKLVDENEKLNEIISQYINSS 813

Query: 534  KLKLKQMQKTIDNFSKVS--DSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSG 591
               L        N SK++    ++E +++ + L + ++   + EE+  NL   +    + 
Sbjct: 814  NTDLLNSMAINKNTSKLNIVKDDEEKLQMFDSLQNCNK---DYEEKIKNL---IAQNKNL 867

Query: 592  RMIESDVYKKMIEM-ENL--AETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADIS 648
              +  D+ K  IE+ ENL   E R K I   E Q  DL  E+  L  K +    ++AD  
Sbjct: 868  EEVILDLEKDKIELAENLQFMEDRQKVI---EKQNDDLQMEIEKL-SKQETACTEIADKV 923

Query: 649  QLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMN 708
            +L   Q  ++   + +++    L+   +E  L+++  + +K      I++       +  
Sbjct: 924  KLLESQ--NQDLHLQIDQMNQGLTQKSEENQLIVQQNENNKNYFEQIIQEKIEQINRLSQ 981

Query: 709  KLQ---NYI---QENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQE--- 759
            +LQ   N+I   Q+   +    E+   E+  E   K  +++Q+    ++  D +I E   
Sbjct: 982  QLQEQSNFIQALQQQQQIQQIHEREEDEQEEEKTKKAANKKQTLPSQRYQRDDQISEDED 1041

Query: 760  -RDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTI 818
               +  +N E+ +    S   +L E     ++    +E   D     L + QK   E   
Sbjct: 1042 QEQIQQQNQENNIKSADSTFNQLNEDNYFDKESEQLIETPLDSNTFELTKFQKELKE--- 1098

Query: 819  QEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNA 878
             +++++  L   +D  +   +Q+ E+   N+++Q++   +++  + ++ S +++ Q    
Sbjct: 1099 -KNDIIKNLCENLDFQK---EQVSEL---NEKVQQQAIFIIDLQEKIKKSQNEINQQGEK 1151

Query: 879  LVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIES 938
            ++E  +     +S S K Q + R++ S       ++   ++Q++ E +D  I+    +  
Sbjct: 1152 ILELLSNASEDQSIS-KSQRKSREIAS------QQNDQELLQQQLEYKDHAIQEYILVIR 1204

Query: 939  AIRDKKVLNEKYEKNIE---------YVTQLEAQLQEYKNNIENLNMNVEELNKMNLELI 989
             + DK +  +K  K ++         Y+ +LE+ L     NI N N+   ++ +M   ++
Sbjct: 1205 ELDDKIINLQKLLKELKPDLQLDNSFYIERLES-LNLLSPNISN-NLKERKITQMEERIL 1262

Query: 990  ----------DKHVQKQQTQSPDYTEQYIN-EINKLNALLKQKDEEI-IALNQKINNAQV 1037
                      D H ++Q   +P   +  I+ EI++ +   KQK EE+   ++  IN    
Sbjct: 1263 IQVQQQDNDEDNHQKQQNLINPQKIQSLIDREISQFDQKYKQKMEELEKEMSVSINERDE 1322

Query: 1038 SYMSMVSDYESKLAQFT------TKLENMEEEMQRVSKQLLDSK---QHNEELQILVREQ 1088
              +S++++   KL Q         K+ N + EM R  + + D+K      +++Q+++ + 
Sbjct: 1323 KIVSLINE-NQKLLQLNEQRLIELKILNQQIEM-RKEQNIRDTKTIEDLQKKIQMMLSKN 1380

Query: 1089 DDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEE 1148
              Q K + +    F+ N   +E  +I S  E  S+++ +VD             + +  +
Sbjct: 1381 IQQNKGILKNSQHFQQN--TSERSLIDSIREEESEESQDVDSQKNQQQHASQSHEAKRLQ 1438

Query: 1149 EFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNT 1208
              ++E+   + Q +    EL+    K++  E +   LT  +   QE++ +L       ++
Sbjct: 1439 RKLEEK---RRQLSDAKQELENLKEKLLDFEEIEFRLTSENRQLQEEVRRLSQ-----HS 1490

Query: 1209 ENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLS---AFE 1265
            + +N L+ + + R +  + + +R FE     +  L Q+  D Q  +     QL+   +F 
Sbjct: 1491 DENNRLNEMLKTRKNEYTELKKR-FEALRAERDELIQKLKDSQFQDGSPSNQLNNSKSFN 1549

Query: 1266 SKYEQLLDSVQSSTQE--ETNKI--VTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIE 1321
                +L   ++S  +E  E  KI    + Q+   + ++ +K E L  ++ K  ++  QI+
Sbjct: 1550 VNSFELYKEIESIKKENHELKKINEQCIVQIKKKEKEIDEKMEELDQVKNKCNELTEQIK 1609

Query: 1322 ILRS 1325
               S
Sbjct: 1610 TSNS 1613



 Score = 95.1 bits (226), Expect = 1e-17
 Identities = 180/878 (20%), Positives = 388/878 (44%), Gaps = 102/878 (11%)

Query: 389  LSSETLNQDTDK-KINKNEIAKLEMV--IQSLNKDLVDK-EYVISEKDTXXXXXXXXXXG 444
            L+S  +N++T K  I K++  KL+M   +Q+ NKD  +K + +I++              
Sbjct: 818  LNSMAINKNTSKLNIVKDDEEKLQMFDSLQNCNKDYEEKIKNLIAQNKNLEEVILDLEKD 877

Query: 445  KDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEK 504
            K  L   LQ      ME    +    N +   EI K+ +Q          +    ++ +K
Sbjct: 878  KIELAENLQF-----MEDRQKVIEKQNDDLQMEIEKLSKQ----------ETACTEIADK 922

Query: 505  LKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSK-VSDSNKEIVRLTEE 563
            +K  E Q   L+ +ID  N+ + +    ++L ++Q +   + F + + +  ++I RL+++
Sbjct: 923  VKLLESQNQDLHLQIDQMNQGLTQKSEENQLIVQQNENNKNYFEQIIQEKIEQINRLSQQ 982

Query: 564  LHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQK 623
            L   S  +  L++++   Q+H  + +     E    K   + + L   R +    + S+ 
Sbjct: 983  LQEQSNFIQALQQQQQIQQIH--EREEDEQEEEKTKKAANKKQTLPSQRYQRDDQI-SED 1039

Query: 624  FDLVQELHILQQKYDEVEDKLAD--ISQLQSDQVCSEIKSVHLEEQIDALSASKKELALV 681
             D  Q    +QQ+  E   K AD   +QL  D    +     +E  +D   ++  EL   
Sbjct: 1040 EDQEQ----IQQQNQENNIKSADSTFNQLNEDNYFDKESEQLIETPLD---SNTFELTKF 1092

Query: 682  IENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQEN----MDLTDKLEK------MSAEK 731
             + LK   + +    ++L+  KE + ++L   +Q+     +DL +K++K         EK
Sbjct: 1093 QKELKEKNDIIKNLCENLDFQKEQV-SELNEKVQQQAIFIIDLQEKIKKSQNEINQQGEK 1151

Query: 732  ISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAV---M 788
            I ELL+  + ++      +   +   Q+ D   E ++ +L +YK     ++E I V   +
Sbjct: 1152 ILELLSNASEDQSISKSQRKSREIASQQNDQ--ELLQQQL-EYKDH--AIQEYILVIREL 1206

Query: 789  EDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHEN 848
            +D+  +L++   +L   LQ     Y    I+  E +N L+  + ++ + E+++ ++E E 
Sbjct: 1207 DDKIINLQKLLKELKPDLQLDNSFY----IERLESLNLLSPNISNN-LKERKITQME-ER 1260

Query: 849  KELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTD-----LAESESTKYQTQLRDL 903
              +Q + Q   E+N   Q +L + Q+  + +  + ++ D       E    +    + + 
Sbjct: 1261 ILIQVQQQDNDEDNHQKQQNLINPQKIQSLIDREISQFDQKYKQKMEELEKEMSVSINER 1320

Query: 904  ESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQI----ESAIRDKKVLNEKYEKNIEYVTQ 959
            +  +  + +E+Q L+   ++ + +L+I  N QI    E  IRD K + E  +K I+ +  
Sbjct: 1321 DEKIVSLINENQKLLQLNEQRLIELKI-LNQQIEMRKEQNIRDTKTI-EDLQKKIQMM-- 1376

Query: 960  LEAQLQEYK---NNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYI---NEINK 1013
            L   +Q+ K    N ++   N  E + ++    ++  + Q   S    +Q+    +E  +
Sbjct: 1377 LSKNIQQNKGILKNSQHFQQNTSERSLIDSIREEESEESQDVDSQKNQQQHASQSHEAKR 1436

Query: 1014 LNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLD 1073
            L   L++K  ++    Q++ N +   +    D+E    + T++   ++EE++R+S+    
Sbjct: 1437 LQRKLEEKRRQLSDAKQELENLKEKLL----DFEEIEFRLTSENRQLQEEVRRLSQH--- 1489

Query: 1074 SKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXX 1133
                N  L  +++ + ++  ELK+    FE  +      +I    +    D +  +    
Sbjct: 1490 -SDENNRLNEMLKTRKNEYTELKK---RFEA-LRAERDELIQKLKDSQFQDGSPSNQLNN 1544

Query: 1134 XXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQ 1193
                     ++ +E E I++ +    +  K+N   ++C   I+Q++    E+        
Sbjct: 1545 SKSFNVNSFELYKEIESIKKEN---HELKKIN---EQC---IVQIKKKEKEID----EKM 1591

Query: 1194 EQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQR 1231
            E+++Q+K+K  +L TE     ++  +   +I    DQ+
Sbjct: 1592 EELDQVKNKCNEL-TEQIKTSNSAPQSICTIQGQEDQK 1628



 Score = 81.0 bits (191), Expect = 2e-13
 Identities = 159/782 (20%), Positives = 332/782 (42%), Gaps = 72/782 (9%)

Query: 839  KQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQT 898
            K+L E+E + KEL  +N  L E  +     L  +Q     LV+K     L E+   K + 
Sbjct: 579  KKLRELEEQVKELVNENSKLSELLEEKGYLLQQIQD--EQLVQKL----LIENNELKEKL 632

Query: 899  QLRDLESNL---KRITHEHQT----LIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYE 951
            +   +E++L    R+ H   T    ++ +K KEI +L+ +     +S    +KV  ++ E
Sbjct: 633  RQAQMENDLSIQNRVLHTENTNLNKILSEKVKEIRELKEKLQQNSQSQESQRKV--DQLE 690

Query: 952  KNIEYVTQ----LEAQLQEYKNNIE-NLNMNVEELNK-MNLELIDKHVQKQQTQSPDYTE 1005
            +NI+ + Q    L   L++ ++ ++   + N+E  NK +NL+   + +Q+QQ++    + 
Sbjct: 691  RNIKLLIQENEHLSDVLKQRQSEVQKQRDDNLEMQNKVINLQSYIQELQEQQSRQQSISN 750

Query: 1006 QYIN----EINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKL-ENM 1060
            +  N    E +K+   L +K+ E   L QK  NAQ        D  +KL     KL E +
Sbjct: 751  EKFNSLKSEYDKIQNKLAEKEHE---LQQKEQNAQ-KINREAEDQITKLVDENEKLNEII 806

Query: 1061 EEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEP 1120
             + +   +  LL+S   N+    L   +DD+ K      L    N  K     I + I  
Sbjct: 807  SQYINSSNTDLLNSMAINKNTSKLNIVKDDEEKLQMFDSL---QNCNKDYEEKIKNLI-- 861

Query: 1121 MSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLET 1180
                A N +            +++ E  +F+++R   Q+   K N +LQ    K+ + ET
Sbjct: 862  ----AQNKNLEEVILDLEKDKIELAENLQFMEDR---QKVIEKQNDDLQMEIEKLSKQET 914

Query: 1181 LNTELTGHDVVNQEQINQLKSKLEQLN------TENDNLLSTVAELRSSISSAVDQRGFE 1234
              TE+     + + Q   L  +++Q+N      +E + L+    E   +    + Q   E
Sbjct: 915  ACTEIADKVKLLESQNQDLHLQIDQMNQGLTQKSEENQLIVQQNENNKNYFEQIIQEKIE 974

Query: 1235 IAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEE----TNKIVTME 1290
                  Q L ++    Q  + + ++Q      + EQ  +  + +  ++    + +    +
Sbjct: 975  QINRLSQQLQEQSNFIQALQQQQQIQQIHEREEDEQEEEKTKKAANKKQTLPSQRYQRDD 1034

Query: 1291 QVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXX 1350
            Q++  +++ Q ++++  N  +      NQ+       ++ +                   
Sbjct: 1035 QISEDEDQEQIQQQNQENNIKSADSTFNQLNEDNYFDKESEQLIETPLDSNTFELTKFQK 1094

Query: 1351 DLRTENQSYKQM------QEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLE 1404
            +L+ +N   K +      Q++ +  +NE+  Q                  +N    K+LE
Sbjct: 1095 ELKEKNDIIKNLCENLDFQKEQVSELNEKVQQQAIFIIDLQEKIKKSQNEINQQGEKILE 1154

Query: 1405 LTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIED-LTYEKESELAILR 1463
            L      +D  I +   +     +Q+ND+ E ++QQL   +  I++ +   +E +  I+ 
Sbjct: 1155 LLSNAS-EDQSISKSQRKSREIASQQNDQ-ELLQQQLEYKDHAIQEYILVIRELDDKIIN 1212

Query: 1464 L-KMHENANHYETMQKESEIERVKLIEELNVKITESVSLNK--QVAE--LNKALEEEVAK 1518
            L K+ +       +     IER++ +  L+  I+ ++   K  Q+ E  L +  +++  +
Sbjct: 1213 LQKLLKELKPDLQLDNSFYIERLESLNLLSPNISNNLKERKITQMEERILIQVQQQDNDE 1272

Query: 1519 TN--EMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTM 1576
             N  + Q  +  Q+I+ + ++ EI+      +    +++K +S + +    RDE++ + +
Sbjct: 1273 DNHQKQQNLINPQKIQSL-IDREISQFDQKYKQKMEELEKEMSVSINE---RDEKIVSLI 1328

Query: 1577 NK 1578
            N+
Sbjct: 1329 NE 1330



 Score = 39.1 bits (87), Expect = 0.99
 Identities = 44/199 (22%), Positives = 95/199 (47%), Gaps = 21/199 (10%)

Query: 1395 VNDAEAKVLELTHQL-EL--KDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDL 1451
            +N    K+ EL  Q+ EL  ++S++ +   E    L Q  DE + V++ L+E  +  E L
Sbjct: 574  LNSNSKKLRELEEQVKELVNENSKLSELLEEKGYLLQQIQDE-QLVQKLLIENNELKEKL 632

Query: 1452 TY-EKESELAILRLKMH-ENANHYETMQKESEIERVKLIEELNVKI---TESVSLNKQVA 1506
               + E++L+I    +H EN N  + +      E+VK I EL  K+   ++S    ++V 
Sbjct: 633  RQAQMENDLSIQNRVLHTENTNLNKILS-----EKVKEIRELKEKLQQNSQSQESQRKVD 687

Query: 1507 ELNKALEEEVAKTNEMQTALENQEIEI-------VTLNDEITNLQNMVRASSSKIQKHVS 1559
            +L + ++  + +   +   L+ ++ E+       + + +++ NLQ+ ++    +  +  S
Sbjct: 688  QLERNIKLLIQENEHLSDVLKQRQSEVQKQRDDNLEMQNKVINLQSYIQELQEQQSRQQS 747

Query: 1560 FASDTKQGRDEQLDNTMNK 1578
             +++       + D   NK
Sbjct: 748  ISNEKFNSLKSEYDKIQNK 766


>UniRef50_UPI00006CD102 Cluster: Kinesin motor domain containing
            protein; n=1; Tetrahymena thermophila SB210|Rep: Kinesin
            motor domain containing protein - Tetrahymena thermophila
            SB210
          Length = 1593

 Score =  124 bits (299), Expect = 2e-26
 Identities = 218/1116 (19%), Positives = 478/1116 (42%), Gaps = 108/1116 (9%)

Query: 494  KDVNV-KDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNF-SKVS 551
            +DV++ K L +K    EE I+ L  EID      I+  +   +KL++ ++   +F SK+ 
Sbjct: 470  QDVDIIKALTQKSDMEEEGISSLLTEIDQTIVEDIQQMTQTCIKLEEFEERRKDFTSKLE 529

Query: 552  DSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAET 611
                      E+   L + +  ++ EK  ++L        ++    + +   + ++  E 
Sbjct: 530  KIGLMNFGCPEKEKELEEAI--IQREKRIIELQNEQAHQNKLFNQQLEEISNQRDHFKEV 587

Query: 612  RLKAISLLESQKFDLVQELHILQQKYDE----VEDKLADISQLQSDQVCSEIKSVHLEEQ 667
                 S ++S +  + + +   ++K  +     E KLA+  Q  S+    +IK++ L ++
Sbjct: 588  NQGLNSEIQSLQQQIAKNVQTHEEKIQQFKNGFESKLAEYDQNSSE---IKIKNMELADE 644

Query: 668  IDALSASKKELALVIENLKLDKEQLY-------GTIKDLENDKEDIMNKLQNYIQENMDL 720
            ID L +  + L  + +++K   E  Y        T  ++EN K+ I ++L    +EN +L
Sbjct: 645  IDELKSHIENLNRIKDDIKQKWENAYENYQKTLQTKNEIENQKDSIQSQLNISREENTNL 704

Query: 721  TDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICR 780
              KL +       + L  +  E++   Q    I  K  + +  +  IE E  + ++ I +
Sbjct: 705  MFKLSEAENLYNQDRLHMMTLEDELNSQKNI-IQEKDHQINNLVSRIEEENLRLQATIDK 763

Query: 781  LEESIAVMEDR----RYSLE---RKADQLGSYLQEK-------QKAYSEYTIQEDELVNR 826
             ++ IA +ED+    +  +E   +  + L   L+EK       Q+ Y +   Q ++  N 
Sbjct: 764  QKDDIASLEDQITKSKEDIEIACQTLEFLNKQLEEKCQVNIQLQETYKQEFNQREKFENE 823

Query: 827  LAVLMDHDR-----------VVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQH 875
            L  L  +++           + EKQ+ EIE E  +   K   L  +   LQ  L + ++ 
Sbjct: 824  LKYLYHNEKSQLNVALKQNEIFEKQIQEIEQEITQKMDKITDLEHDILGLQEKLKNNEKR 883

Query: 876  YNAL-VEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNT 934
             N+L VEK    +  E+E    Q Q++D    +K I    +T + Q  +++E    E+  
Sbjct: 884  LNSLEVEKEYYRN--ETEQQIQQIQIKD--DKIKEINQALETAL-QMGEQLEMGVQEYEK 938

Query: 935  QIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQ 994
            Q        K+L+E+  +  + + +   QL++ +  I    M  E L +   EL +  + 
Sbjct: 939  Q-------NKILSEQLLQKEQEILEKILQLEDAEQKIRVSQMTHELLTQKISEL-ESQLG 990

Query: 995  KQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFT 1054
            +Q T +  + +Q +    +   L+ QK+ ++I  N +     +     +   E    +  
Sbjct: 991  EQITLNTGFQDQIVLLSEEKKDLI-QKEAQLIESNLEQEKTIIELKENLQQLEQLCKEKE 1049

Query: 1055 TKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMII 1114
            T++E ++ +   + K   D +Q  +     V+EQ++++ E +     FE+   + +   +
Sbjct: 1050 TQIEQIKSDFYELKKSSEDYQQIQDHELKSVKEQNNKLNE-QVQNYEFEVQNMQQKASQM 1108

Query: 1115 SSTIEPMS---DDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQEC 1171
               +E +     +   +              K Q+ EE IQER V +E+  K+ T+    
Sbjct: 1109 EEDMEVLKQEIQEKQELYLQSEKSKEEQISQKNQKIEELIQERQVYEEEFDKIQTKYSNQ 1168

Query: 1172 YTKIIQL-ETLNTELTGHDVVNQE-QINQLKSKLEQLNTENDNLLSTVAELRSSIS-SAV 1228
               I +L ++     T ++ + ++ + N++   L+Q+  +N+NL+      +  +    +
Sbjct: 1169 MRNISELQQSFQAARTENESIKKQIEDNRVFIYLQQIQ-QNENLMIHFCNKKGQMEIFQL 1227

Query: 1229 DQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVT 1288
            +++ FEI    KQ L       Q+  ++  + +  F+ + EQ+    +    +  ++ + 
Sbjct: 1228 EKQKFEIE---KQKLETERQTIQQEMYQKDILIQKFKEEQEQI--GCKFEIFKTLHEQIE 1282

Query: 1289 MEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXX 1348
             EQ    Q+K  +K + L N ++KY  +   +E L     +EK+                
Sbjct: 1283 -EQKNVYQSKYVNKSKELDNYEQKYNTLEQAMERL-----NEKLTIKQLENNKLTNQILI 1336

Query: 1349 XXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQ 1408
                R +NQ  ++  ++ +    EE +Q+K+                   + K L L  Q
Sbjct: 1337 MQSNREKNQFTQEDLQRDLKKSREECSQIKQ-------------------KYKALILERQ 1377

Query: 1409 LELKDSEIYQ-KTHEYTITLTQRNDEFENVRQQLVEY----EKRIEDLTYEKESELAILR 1463
            ++ + +  +    ++  I + +  +E   ++ Q  +Y    EK+I ++  +    ++   
Sbjct: 1378 VQSQQANRFNGNANDQNIIIKKLEEENNKIKDQFNKYKQISEKKINEICEKLNRGISTAT 1437

Query: 1464 LKMHENANHYETMQKESEIERVKLIEELNVKITE-SVSLNKQVAELNKALEEEVAKTNEM 1522
            + + + +N  E  +K    ++ ++I E N+ I E ++ +   + +  K   +   K +E 
Sbjct: 1438 I-VKDISNSTEIAKKLE--KQCEIINEKNMGILEINILVRNYLIDCKKGQIDPTQK-DEY 1493

Query: 1523 QTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHV 1558
               +++QE +   L + ++++   V     K+Q+ +
Sbjct: 1494 LEKIQSQE-DTTALKEVLSSVLKSVEERERKVQQEM 1528



 Score =  115 bits (276), Expect = 1e-23
 Identities = 207/1075 (19%), Positives = 454/1075 (42%), Gaps = 92/1075 (8%)

Query: 481  VQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQM 540
            ++ Q +Q   +++ +  ++++  +    +E    LN EI +  + + K    H+ K++Q 
Sbjct: 557  IELQNEQAHQNKLFNQQLEEISNQRDHFKEVNQGLNSEIQSLQQQIAKNVQTHEEKIQQF 616

Query: 541  QKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYK 600
            +   ++     D N   +++      L+ ++ EL+    NL     D         + Y+
Sbjct: 617  KNGFESKLAEYDQNSSEIKIKN--MELADEIDELKSHIENLNRIKDDIKQKWENAYENYQ 674

Query: 601  KMI----EMENLAETRLKAISLLESQKFDLVQELHILQQKYDE-------VEDKL---AD 646
            K +    E+EN  ++    +++   +  +L+ +L   +  Y++       +ED+L    +
Sbjct: 675  KTLQTKNEIENQKDSIQSQLNISREENTNLMFKLSEAENLYNQDRLHMMTLEDELNSQKN 734

Query: 647  ISQLQSDQVCSEIKSVHLEE-QIDA-LSASKKELALVIENLKLDKEQLYGTIKDLENDKE 704
            I Q +  Q+ + +  +  E  ++ A +   K ++A + + +   KE +    + LE   +
Sbjct: 735  IIQEKDHQINNLVSRIEEENLRLQATIDKQKDDIASLEDQITKSKEDIEIACQTLEFLNK 794

Query: 705  DIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYI 764
             +  K Q  IQ  +  T K E    EK    L  + H E+S++      +   +++   I
Sbjct: 795  QLEEKCQVNIQ--LQETYKQEFNQREKFENELKYLYHNEKSQLNVALKQNEIFEKQ---I 849

Query: 765  ENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQL----GSYLQEKQKAYSEYTIQE 820
            + IE E+++   +I  LE  I  ++++  + E++ + L      Y  E ++   +  I++
Sbjct: 850  QEIEQEITQKMDKITDLEHDILGLQEKLKNNEKRLNSLEVEKEYYRNETEQQIQQIQIKD 909

Query: 821  DEL--VNR-LAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQ--ISLSDMQQH 875
            D++  +N+ L   +     +E  + E E +NK L +  Q+L +E + L+  + L D +Q 
Sbjct: 910  DKIKEINQALETALQMGEQLEMGVQEYEKQNKILSE--QLLQKEQEILEKILQLEDAEQK 967

Query: 876  YNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQ 935
                V +    +L   + ++ ++QL + +  L     +   L+ ++KK++   E +    
Sbjct: 968  IR--VSQMTH-ELLTQKISELESQLGE-QITLNTGFQDQIVLLSEEKKDLIQKEAQL--- 1020

Query: 936  IESAIRDKKVLNEKYEKNIEYVTQL----EAQLQEYKNNIENLNMNVEELNKMNLELIDK 991
            IES +  +K + E  ++N++ + QL    E Q+++ K++   L  + E+  ++    + K
Sbjct: 1021 IESNLEQEKTIIE-LKENLQQLEQLCKEKETQIEQIKSDFYELKKSSEDYQQIQDHEL-K 1078

Query: 992  HVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLA 1051
             V++Q  +  +  + Y  E+  +     Q +E++  L Q+I   Q  Y+      E +++
Sbjct: 1079 SVKEQNNKLNEQVQNYEFEVQNMQQKASQMEEDMEVLKQEIQEKQELYLQSEKSKEEQIS 1138

Query: 1052 QFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEG 1111
            Q   K+E + +E Q           + EE   +  +  +Q++ + E + +F+    +TE 
Sbjct: 1139 QKNQKIEELIQERQ----------VYEEEFDKIQTKYSNQMRNISELQQSFQ--AARTEN 1186

Query: 1112 MIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTE---- 1167
              I   IE                       K  + E F  E+   + +  KL TE    
Sbjct: 1187 ESIKKQIEDNRVFIYLQQIQQNENLMIHFCNKKGQMEIFQLEKQKFEIEKQKLETERQTI 1246

Query: 1168 LQECYTKIIQLETLNTE-----------LTGHDVVNQEQINQLKSKLEQLNTENDNL--- 1213
             QE Y K I ++    E            T H+ + +EQ N  +SK    + E DN    
Sbjct: 1247 QQEMYQKDILIQKFKEEQEQIGCKFEIFKTLHEQI-EEQKNVYQSKYVNKSKELDNYEQK 1305

Query: 1214 LSTVAELRSSISSAVDQRGFEIAELWKQHL---AQREADFQKTEHELRVQLSAFESKYEQ 1270
             +T+ +    ++  +  +  E  +L  Q L   + RE + Q T+ +L+  L     +  Q
Sbjct: 1306 YNTLEQAMERLNEKLTIKQLENNKLTNQILIMQSNREKN-QFTQEDLQRDLKKSREECSQ 1364

Query: 1271 LLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDE 1330
            +    ++   E   + V  +Q         D+   ++ L+E+   + +Q    + +I ++
Sbjct: 1365 IKQKYKALILE---RQVQSQQANRFNGNANDQNIIIKKLEEENNKIKDQFNKYK-QISEK 1420

Query: 1331 KVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXX 1390
            K+                  D+    +  K++++Q  + INE+N  + + +         
Sbjct: 1421 KINEICEKLNRGISTATIVKDISNSTEIAKKLEKQCEI-INEKNMGILEINILVRNYLID 1479

Query: 1391 XXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIED 1450
                  D   K   L      +D+   ++     +   +  +    V+Q++ + +++   
Sbjct: 1480 CKKGQIDPTQKDEYLEKIQSQEDTTALKEVLSSVLKSVEERE--RKVQQEMYQLKEKKAS 1537

Query: 1451 LTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQV 1505
              Y + S+   L  + +E  N  ET +K    +R   ++E  V I   + LNK+V
Sbjct: 1538 YEYYR-SKCEELEFR-YEKKNS-ETGEKILNRKRKLSVKENEVPILGEIDLNKKV 1589



 Score =  102 bits (244), Expect = 9e-20
 Identities = 169/839 (20%), Positives = 370/839 (44%), Gaps = 69/839 (8%)

Query: 479  AKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLK 538
            +K+ E  +     +IK++ + D I++LKS  E + ++ D+I    +N  +   N++ K  
Sbjct: 622  SKLAEYDQNSSEIKIKNMELADEIDELKSHIENLNRIKDDIKQKWENAYE---NYQ-KTL 677

Query: 539  QMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDV 598
            Q +  I+N      S   I R  EE  +L  K++E E      +LH++  +     E + 
Sbjct: 678  QTKNEIENQKDSIQSQLNISR--EENTNLMFKLSEAENLYNQDRLHMMTLED----ELNS 731

Query: 599  YKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSE 658
             K +I+ ++     L  +S +E +          LQ   D+ +D   DI+ L+ DQ+   
Sbjct: 732  QKNIIQEKDHQINNL--VSRIEEENLR-------LQATIDKQKD---DIASLE-DQITKS 778

Query: 659  IKSVHLE-EQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQEN 717
             + + +  + ++ L+   +E   V   L+   +Q +   +  EN+ + + +  ++ +   
Sbjct: 779  KEDIEIACQTLEFLNKQLEEKCQVNIQLQETYKQEFNQREKFENELKYLYHNEKSQLNVA 838

Query: 718  MDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSR 777
            +   +  EK   E   E+  K++     +     G+  K++  +  + ++E E   Y++ 
Sbjct: 839  LKQNEIFEKQIQEIEQEITQKMDKITDLE-HDILGLQEKLKNNEKRLNSLEVEKEYYRNE 897

Query: 778  ICRLEESIAVMEDRRYSLERKAD---QLGSYLQ------EKQ-KAYSEYTIQ-EDELVNR 826
              +  + I + +D+   + +  +   Q+G  L+      EKQ K  SE  +Q E E++ +
Sbjct: 898  TEQQIQQIQIKDDKIKEINQALETALQMGEQLEMGVQEYEKQNKILSEQLLQKEQEILEK 957

Query: 827  LAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRT 886
            +  L D      +Q + +     EL  +    LE     QI+L+   Q    L+ +  + 
Sbjct: 958  ILQLED-----AEQKIRVSQMTHELLTQKISELESQLGEQITLNTGFQDQIVLLSE-EKK 1011

Query: 887  DLAESESTKYQTQLRDLES--NLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKK 944
            DL + E+   ++ L   ++   LK    + + L  +K+ +IE ++ +F  +++ +  D +
Sbjct: 1012 DLIQKEAQLIESNLEQEKTIIELKENLQQLEQLCKEKETQIEQIKSDF-YELKKSSEDYQ 1070

Query: 945  VLNEKYEKNI-EYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQ---TQS 1000
             + +   K++ E   +L  Q+Q Y+  ++N+     ++ + ++E++ + +Q++Q    QS
Sbjct: 1071 QIQDHELKSVKEQNNKLNEQVQNYEFEVQNMQQKASQMEE-DMEVLKQEIQEKQELYLQS 1129

Query: 1001 PDYTEQYINEIN-KLNALLKQK---DEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTK 1056
                E+ I++ N K+  L++++   +EE   +  K +N     M  +S+ +       T+
Sbjct: 1130 EKSKEEQISQKNQKIEELIQERQVYEEEFDKIQTKYSN----QMRNISELQQSFQAARTE 1185

Query: 1057 LENMEEEMQRVSKQL-LDSKQHNEELQILVREQDDQIK--ELKETKLTFEMNIPKTEGMI 1113
             E+++++++     + L   Q NE L I    +  Q++  +L++ K   E    +TE   
Sbjct: 1186 NESIKKQIEDNRVFIYLQQIQQNENLMIHFCNKKGQMEIFQLEKQKFEIEKQKLETERQT 1245

Query: 1114 ISSTI---EPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQE 1170
            I   +   + +                    L  Q EE+    +S    +S +L+   Q+
Sbjct: 1246 IQQEMYQKDILIQKFKEEQEQIGCKFEIFKTLHEQIEEQKNVYQSKYVNKSKELDNYEQK 1305

Query: 1171 CYTKIIQLETLNTELTGHDVVNQEQINQ---LKSKLEQLNTENDNLLSTVAELRSSISSA 1227
              T    +E LN +LT   + N +  NQ   ++S  E+     ++L   + + R   S  
Sbjct: 1306 YNTLEQAMERLNEKLTIKQLENNKLTNQILIMQSNREKNQFTQEDLQRDLKKSREECSQ- 1364

Query: 1228 VDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKI 1286
            + Q+ ++   L +Q  +Q+   F    ++  + +   E +  ++ D      Q    KI
Sbjct: 1365 IKQK-YKALILERQVQSQQANRFNGNANDQNIIIKKLEEENNKIKDQFNKYKQISEKKI 1422



 Score = 96.7 bits (230), Expect = 5e-18
 Identities = 196/1062 (18%), Positives = 428/1062 (40%), Gaps = 76/1062 (7%)

Query: 507  SAEEQITQLNDEIDAANKNMIKVKSN--HKLKLKQMQKTIDNFSKVSDSNKEIVRLTEEL 564
            S    +  LN +    +  MI VK++  H + L   ++   +     D  KE   + + L
Sbjct: 219  SRSHSVFSLNFQSKIVSNGMIHVKNSKLHFVDLAGSERQ-KSTGAAGDRLKEASNINKSL 277

Query: 565  HHLSQKVAELEEEKGNLQLHLVDYDSG-RMIESDVY---KKMIEMENLAETRLKAISLLE 620
              L   +  L E       H+   DS    I  D      +   +   +E   +    L 
Sbjct: 278  TVLGLVINALVESANGKSRHIPYRDSKLTFILKDSLGGNSRTFMIAACSEANTQFQETLS 337

Query: 621  SQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELAL 680
            + KF   Q   +++ K    E+   ++ QL+ +    + +    ++ +  +  ++K +  
Sbjct: 338  TLKF--AQRAKMIKNKASVNEESQGNVQQLKKEIQKLKEELQDAKKALQEMEENQKNMTR 395

Query: 681  VIENLKLDKEQLY--GTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAK 738
            +I   K     +     I+  + + ++I  KL+   Q   D  D   ++     +E L  
Sbjct: 396  IITPAKYTPTSMNHEAVIQFQQKNFKEINIKLEEVNQLLSDFNDSRSRIEEFFKNEKLGV 455

Query: 739  INHEEQSKIQTQFGIDAKI-----QERDLYIENIESELSKYKSRICRLEESIAVMEDRRY 793
            +   +    Q + G D  I     Q+ D+  E I S L++    I    E I  M     
Sbjct: 456  LRVFQDIVDQKKMGQDVDIIKALTQKSDMEEEGISSLLTEIDQTIV---EDIQQMTQTCI 512

Query: 794  SLERKADQLGSYLQEKQK-AYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQ 852
             LE   ++   +  + +K     +   E E     A++    R++E Q  E  H+NK   
Sbjct: 513  KLEEFEERRKDFTSKLEKIGLMNFGCPEKEKELEEAIIQREKRIIELQN-EQAHQNKLFN 571

Query: 853  KKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESEST---KYQTQLRDLESNLKR 909
            ++    LEE  N +    ++ Q  N+ ++   +  +A++  T   K Q      ES L  
Sbjct: 572  QQ----LEEISNQRDHFKEVNQGLNSEIQSLQQ-QIAKNVQTHEEKIQQFKNGFESKLAE 626

Query: 910  ITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYE---KNIEYVTQLEAQLQE 966
                   + + K  E+ D   E  + IE+  R K  + +K+E   +N +   Q + +++ 
Sbjct: 627  YDQNSSEIKI-KNMELADEIDELKSHIENLNRIKDDIKQKWENAYENYQKTLQTKNEIEN 685

Query: 967  YKNNIEN-LNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEI 1025
             K++I++ LN++ EE   +  +L +      Q +    T +  +E+N    ++++KD +I
Sbjct: 686  QKDSIQSQLNISREENTNLMFKLSEAENLYNQDRLHMMTLE--DELNSQKNIIQEKDHQI 743

Query: 1026 IALNQKINNAQVSYMSMVSDYESKLA----QFTTKLENME---EEMQRVSKQLLDSKQHN 1078
              L  +I    +   + +   +  +A    Q T   E++E   + ++ ++KQL +  Q N
Sbjct: 744  NNLVSRIEEENLRLQATIDKQKDDIASLEDQITKSKEDIEIACQTLEFLNKQLEEKCQVN 803

Query: 1079 EELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXX 1138
             +LQ   +++ +Q +E  E +L +  +  K++  +     E        ++         
Sbjct: 804  IQLQETYKQEFNQ-REKFENELKYLYHNEKSQLNVALKQNEIFEKQIQEIE--------- 853

Query: 1139 XXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQ 1198
                  QE  + + + + L+     L  +L+    ++  LE +  E   ++   Q Q  Q
Sbjct: 854  ------QEITQKMDKITDLEHDILGLQEKLKNNEKRLNSLE-VEKEYYRNETEQQIQQIQ 906

Query: 1199 LKS-KLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHEL 1257
            +K  K++++N   +  L    +L   +     Q      +L ++     E   Q  + E 
Sbjct: 907  IKDDKIKEINQALETALQMGEQLEMGVQEYEKQNKILSEQLLQKEQEILEKILQLEDAEQ 966

Query: 1258 RVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVI 1317
            ++++S       +LL    S  + +  + +T+   T  Q+++    E  ++L +K A +I
Sbjct: 967  KIRVSQMT---HELLTQKISELESQLGEQITLN--TGFQDQIVLLSEEKKDLIQKEAQLI 1021

Query: 1318 -NQIEILRSEIE-----DEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNIN 1371
             + +E  ++ IE      +                    +L+  ++ Y+Q+Q+  + ++ 
Sbjct: 1022 ESNLEQEKTIIELKENLQQLEQLCKEKETQIEQIKSDFYELKKSSEDYQQIQDHELKSVK 1081

Query: 1372 EENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRN 1431
            E+N +L +              + +  E  +  L  +++ K     Q        ++Q+N
Sbjct: 1082 EQNNKLNEQVQNYEFEVQNMQQKASQMEEDMEVLKQEIQEKQELYLQSEKSKEEQISQKN 1141

Query: 1432 DEFENVRQQLVEYEKRIEDLTYEKESELA-ILRLKMHENANHYETMQKESEIERVKLIEE 1490
             + E + Q+   YE+  + +  +  +++  I  L+    A   E    + +IE  ++   
Sbjct: 1142 QKIEELIQERQVYEEEFDKIQTKYSNQMRNISELQQSFQAARTENESIKKQIEDNRVFIY 1201

Query: 1491 LNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIE 1532
            L  +I ++ +L   +   NK  + E+ +  + +  +E Q++E
Sbjct: 1202 LQ-QIQQNENL--MIHFCNKKGQMEIFQLEKQKFEIEKQKLE 1240



 Score = 94.3 bits (224), Expect = 2e-17
 Identities = 167/928 (17%), Positives = 404/928 (43%), Gaps = 71/928 (7%)

Query: 409  KLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHV 468
            K E   ++  K L  K  + ++KD+              L+   +L   +++     +H+
Sbjct: 665  KWENAYENYQKTLQTKNEIENQKDSIQSQLNISREENTNLM--FKLSEAENLYNQDRLHM 722

Query: 469  GTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEK--LKSAEEQITQLNDEIDAANKNM 526
             T  +++N    + ++   ++N+ +  +  ++L  +  +   ++ I  L D+I  + +++
Sbjct: 723  MTLEDELNSQKNIIQEKDHQINNLVSRIEEENLRLQATIDKQKDDIASLEDQITKSKEDI 782

Query: 527  IKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLV 586
                   +   KQ+++      ++ ++ K+     E+  +  + +   E+ + N+ L   
Sbjct: 783  EIACQTLEFLNKQLEEKCQVNIQLQETYKQEFNQREKFENELKYLYHNEKSQLNVALKQN 842

Query: 587  DYDSGRM--IESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKY-DEVEDK 643
            +    ++  IE ++ +KM ++ +L    L     L++ +  L   L + ++ Y +E E +
Sbjct: 843  EIFEKQIQEIEQEITQKMDKITDLEHDILGLQEKLKNNEKRL-NSLEVEKEYYRNETEQQ 901

Query: 644  LADISQLQSDQVCSEIK-----SVHLEEQID-ALSASKKELALVIENLKLDKEQLYGTIK 697
            +  I Q++ D++  EI      ++ + EQ++  +   +K+  ++ E L   ++++   I 
Sbjct: 902  IQQI-QIKDDKI-KEINQALETALQMGEQLEMGVQEYEKQNKILSEQLLQKEQEILEKIL 959

Query: 698  DLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKI 757
             LE+ ++ I  ++     E   LT K+ ++ ++   ++      ++Q  + ++   D   
Sbjct: 960  QLEDAEQKI--RVSQMTHEL--LTQKISELESQLGEQITLNTGFQDQIVLLSEEKKDLIQ 1015

Query: 758  QERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYT 817
            +E  L   N+E E +     I  L+E++  +E      E + +Q+ S   E +K+  +Y 
Sbjct: 1016 KEAQLIESNLEQEKT-----IIELKENLQQLEQLCKEKETQIEQIKSDFYELKKSSEDYQ 1070

Query: 818  -IQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHY 876
             IQ+ EL +    + + +  + +Q+   E E + +Q+K   + E+ + L+  + + Q+ Y
Sbjct: 1071 QIQDHELKS----VKEQNNKLNEQVQNYEFEVQNMQQKASQMEEDMEVLKQEIQEKQELY 1126

Query: 877  NALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEF---- 932
              L  + ++ +    ++ K +  +++ +   +    + QT    + + I +L+  F    
Sbjct: 1127 --LQSEKSKEEQISQKNQKIEELIQERQVYEEEFD-KIQTKYSNQMRNISELQQSFQAAR 1183

Query: 933  --NTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVE--ELNKMNLEL 988
              N  I+  I D +V    Y + I+    L       K  +E   +  +  E+ K  LE 
Sbjct: 1184 TENESIKKQIEDNRVFI--YLQQIQQNENLMIHFCNKKGQMEIFQLEKQKFEIEKQKLET 1241

Query: 989  IDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYES 1048
              + +Q++  Q     +++  E  ++      K E    L+++I   +  Y S   +   
Sbjct: 1242 ERQTIQQEMYQKDILIQKFKEEQEQIGC----KFEIFKTLHEQIEEQKNVYQSKYVNKSK 1297

Query: 1049 KLAQFTTKLENMEEEMQRVSKQLLDSKQHNEEL--QILVRE---------QDDQIKELKE 1097
            +L  +  K   +E+ M+R++++L   +  N +L  QIL+ +         Q+D  ++LK+
Sbjct: 1298 ELDNYEQKYNTLEQAMERLNEKLTIKQLENNKLTNQILIMQSNREKNQFTQEDLQRDLKK 1357

Query: 1098 TKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQER-SV 1156
            ++        K + +I+   ++  S  AN  +             K++EE   I+++ + 
Sbjct: 1358 SREECSQIKQKYKALILERQVQ--SQQANRFNGNANDQNIIIK--KLEEENNKIKDQFNK 1413

Query: 1157 LQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLST 1216
             ++ S K   E+ E   + I   T+  +++     + E   +L+ + E +N +N  +L  
Sbjct: 1414 YKQISEKKINEICEKLNRGISTATIVKDISN----STEIAKKLEKQCEIINEKNMGILEI 1469

Query: 1217 VAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQ 1276
               +R+ +   +D +  +I    K    ++    Q+    L+  LS+     E+    VQ
Sbjct: 1470 NILVRNYL---IDCKKGQIDPTQKDEYLEK-IQSQEDTTALKEVLSSVLKSVEERERKVQ 1525

Query: 1277 SSTQEETNKIVTMEQVTSLQNKLQDKEE 1304
                +   K  + E   S   +L+ + E
Sbjct: 1526 QEMYQLKEKKASYEYYRSKCEELEFRYE 1553



 Score = 53.2 bits (122), Expect = 6e-05
 Identities = 91/447 (20%), Positives = 186/447 (41%), Gaps = 44/447 (9%)

Query: 1143 KVQEEEEFIQE-RSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVV---NQEQINQ 1198
            ++Q+ +E +Q+ +  LQE       E Q+  T+II           H+ V    Q+   +
Sbjct: 368  EIQKLKEELQDAKKALQEME-----ENQKNMTRIITPAKYTPTSMNHEAVIQFQQKNFKE 422

Query: 1199 LKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELR 1258
            +  KLE++N     LLS   + RS I     +  F+  +L    + Q   D +K   ++ 
Sbjct: 423  INIKLEEVN----QLLSDFNDSRSRI-----EEFFKNEKLGVLRVFQDIVDQKKMGQDVD 473

Query: 1259 VQLSAFESKYEQLLDSVQSSTQEETNKIVT-MEQVTSLQNKLQDKEEHLRNLQEKYADVI 1317
            + + A   K +   + + S   E    IV  ++Q+T    KL++ EE  ++   K    +
Sbjct: 474  I-IKALTQKSDMEEEGISSLLTEIDQTIVEDIQQMTQTCIKLEEFEERRKDFTSK----L 528

Query: 1318 NQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQL 1377
             +I ++     +++                   +   +N+ + Q  E+ I N  +   ++
Sbjct: 529  EKIGLMNFGCPEKEKELEEAIIQREKRIIELQNEQAHQNKLFNQQLEE-ISNQRDHFKEV 587

Query: 1378 KKS-SXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFEN 1436
             +  +             V   E K+ +  +  E K +E  Q + E  I   +  DE + 
Sbjct: 588  NQGLNSEIQSLQQQIAKNVQTHEEKIQQFKNGFESKLAEYDQNSSEIKIKNMELADEIDE 647

Query: 1437 VRQQLVEYEKRIEDLTYEKESELAILRLKMHENA--NHYETMQKESEIERVK--LIEELN 1492
            ++   +E   RI+D   +K            ENA  N+ +T+Q ++EIE  K  +  +LN
Sbjct: 648  LKSH-IENLNRIKDDIKQK-----------WENAYENYQKTLQTKNEIENQKDSIQSQLN 695

Query: 1493 VKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSS 1552
            +   E+ +L  +++E      ++      ++  L +Q+  I   + +I NL + +   + 
Sbjct: 696  ISREENTNLMFKLSEAENLYNQDRLHMMTLEDELNSQKNIIQEKDHQINNLVSRIEEENL 755

Query: 1553 KIQKHVSFASDTKQGRDEQLDNTMNKE 1579
            ++Q  +    D     ++Q+  T +KE
Sbjct: 756  RLQATIDKQKDDIASLEDQI--TKSKE 780



 Score = 53.2 bits (122), Expect = 6e-05
 Identities = 145/727 (19%), Positives = 312/727 (42%), Gaps = 71/727 (9%)

Query: 151  IKEKDNALSVLQVKMKIMETTILDLQEKI--NEKD-QIIEAKNKATTXXXXXXXXXXXXX 207
            I+E +  ++    K+  +E  IL LQEK+  NEK    +E + +                
Sbjct: 849  IQEIEQEITQKMDKITDLEHDILGLQEKLKNNEKRLNSLEVEKEYYRNETEQQIQQIQIK 908

Query: 208  XXXXEDTKQQMT---KMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAA- 263
                ++  Q +    +M E       E++ + + L + +  K+  I  LE+  +L +A  
Sbjct: 909  DDKIKEINQALETALQMGEQLEMGVQEYEKQNKILSEQLLQKEQEI--LEKILQLEDAEQ 966

Query: 264  RFEIS-LEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMT 322
            +  +S + H  L Q++ +                 Q +  S E+K  I+++  L  +N+ 
Sbjct: 967  KIRVSQMTHELLTQKISELESQLGEQITLNTGFQDQIVLLSEEKKDLIQKEAQLIESNLE 1026

Query: 323  ELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKM 382
            +    IEL E+L  Q+ Q  KE E ++  + ++   +   S+    +   +        +
Sbjct: 1027 QEKTIIELKENLQ-QLEQLCKEKETQIEQIKSDFYELKKSSEDYQQIQDHE-----LKSV 1080

Query: 383  KSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKE--YVISEKDTXXXXXXX 440
            K   ++L+ +  N + + +  + + +++E  ++ L +++ +K+  Y+ SEK         
Sbjct: 1081 KEQNNKLNEQVQNYEFEVQNMQQKASQMEEDMEVLKQEIQEKQELYLQSEKSKEEQISQ- 1139

Query: 441  XXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQE--QLKQELNDEIKDVNV 498
                K+  I +L  E Q + E    I    + + +  I+++Q+  Q  +  N+ IK   +
Sbjct: 1140 ----KNQKIEELIQERQVYEEEFDKIQTKYSNQ-MRNISELQQSFQAARTENESIKK-QI 1193

Query: 499  KDLIEKLKSAEEQITQL-NDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEI 557
            +D   ++    +QI Q  N  I   NK     K   ++   + QK      K+    + I
Sbjct: 1194 ED--NRVFIYLQQIQQNENLMIHFCNK-----KGQMEIFQLEKQKFEIEKQKLETERQTI 1246

Query: 558  VRLTEELHHLSQKVAELEEEKGNL-----QLHLVDYDSGRMIESDVYKKMIEMENLAETR 612
             +   +   L QK  E +E+ G        LH    +   + +S    K  E++N  +  
Sbjct: 1247 QQEMYQKDILIQKFKEEQEQIGCKFEIFKTLHEQIEEQKNVYQSKYVNKSKELDNYEQK- 1305

Query: 613  LKAISLLESQKFDLVQELHILQQKYDEVEDKLADI-SQLQSDQVCSEIKSVHLEEQIDAL 671
                + LE     L ++L I Q + +++ +++  + S  + +Q   E     L++  +  
Sbjct: 1306 ---YNTLEQAMERLNEKLTIKQLENNKLTNQILIMQSNREKNQFTQEDLQRDLKKSREEC 1362

Query: 672  SASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEK 731
            S  K++   +I   ++  +Q         ND+  I+ KL+    +  D  +K +++S +K
Sbjct: 1363 SQIKQKYKALILERQVQSQQA-NRFNGNANDQNIIIKKLEEENNKIKDQFNKYKQISEKK 1421

Query: 732  ISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRL--EESIAVME 789
            I+E+  K+N           GI      +D  I N  +E++K   + C +  E+++ ++E
Sbjct: 1422 INEICEKLNR----------GISTATIVKD--ISN-STEIAKKLEKQCEIINEKNMGILE 1468

Query: 790  ----DRRYSLERKADQL-----GSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQ 840
                 R Y ++ K  Q+       YL EK ++  + T  ++ L + L  + + +R V+++
Sbjct: 1469 INILVRNYLIDCKKGQIDPTQKDEYL-EKIQSQEDTTALKEVLSSVLKSVEERERKVQQE 1527

Query: 841  LLEIEHE 847
            + +++ +
Sbjct: 1528 MYQLKEK 1534



 Score = 51.6 bits (118), Expect = 2e-04
 Identities = 149/712 (20%), Positives = 279/712 (39%), Gaps = 63/712 (8%)

Query: 143  DVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXX 202
            D+  L   +K  +  L+ L+V+ +          ++I  KD  I+  N+A          
Sbjct: 869  DILGLQEKLKNNEKRLNSLEVEKEYYRNETEQQIQQIQIKDDKIKEINQA----LETALQ 924

Query: 203  XXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEA 262
                     ++ ++Q   + E  +  E E   EK   L+D E K +R+S +       + 
Sbjct: 925  MGEQLEMGVQEYEKQNKILSEQLLQKEQEIL-EKILQLEDAEQK-IRVSQMTHELLTQKI 982

Query: 263  ARFEISL-EHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCE-EKTEIEEKGSLEIAN 320
            +  E  L E   L    +                  Q IE + E EKT IE K +L+   
Sbjct: 983  SELESQLGEQITLNTGFQDQIVLLSEEKKDLIQKEAQLIESNLEQEKTIIELKENLQ--Q 1040

Query: 321  MTELTKKIEL-LEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTA 379
            + +L K+ E  +E +     +  K  E+       E K+V   + K +  +         
Sbjct: 1041 LEQLCKEKETQIEQIKSDFYELKKSSEDYQQIQDHELKSVKEQNNKLNEQVQNYEFEVQN 1100

Query: 380  SKMKSPWSQLSSETLNQDTDKKIN---KNEIAKLEMVIQSLNK--DLVDKEYVISEKDTX 434
             + K+   +   E L Q+  +K     ++E +K E + Q   K  +L+ +  V  E+   
Sbjct: 1101 MQQKASQMEEDMEVLKQEIQEKQELYLQSEKSKEEQISQKNQKIEELIQERQVYEEE--- 1157

Query: 435  XXXXXXXXXGKDTLIAQLQLEHQ-QHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEI 493
                      +   I++LQ   Q    E  S   +    ED N +    +Q++Q  N  I
Sbjct: 1158 FDKIQTKYSNQMRNISELQQSFQAARTENES---IKKQIED-NRVFIYLQQIQQNENLMI 1213

Query: 494  KDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDS 553
               N        K  + +I QL  +     K  ++ +    ++ +  QK I    K  + 
Sbjct: 1214 HFCN--------KKGQMEIFQLEKQKFEIEKQKLETE-RQTIQQEMYQKDI-LIQKFKEE 1263

Query: 554  NKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVY-KKMIEMENLAETR 612
             ++I    E    L +   ++EE+K   Q   V+    +  E D Y +K   +E   E  
Sbjct: 1264 QEQIGCKFEIFKTLHE---QIEEQKNVYQSKYVN----KSKELDNYEQKYNTLEQAMERL 1316

Query: 613  LKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQ--LQSDQVCSEIKSVH----LEE 666
             + +++ + +   L  ++ I+Q   ++ +    D+ +   +S + CS+IK  +    LE 
Sbjct: 1317 NEKLTIKQLENNKLTNQILIMQSNREKNQFTQEDLQRDLKKSREECSQIKQKYKALILER 1376

Query: 667  QIDALSASKKELALVIENLKLDK-EQLYGTIKDLENDKEDIMNKLQNYIQE--NMDLTDK 723
            Q+ +  A++       +N+ + K E+    IKD  N  + I  K  N I E  N  ++  
Sbjct: 1377 QVQSQQANRFNGNANDQNIIIKKLEEENNKIKDQFNKYKQISEKKINEICEKLNRGISTA 1436

Query: 724  LEKMSAEKISELLAKINHEEQSKIQTQFGI-DAKIQERDLYIENIESEL-----SKYKSR 777
                     +E+  K+  + +   +   GI +  I  R+  I+  + ++      +Y  +
Sbjct: 1437 TIVKDISNSTEIAKKLEKQCEIINEKNMGILEINILVRNYLIDCKKGQIDPTQKDEYLEK 1496

Query: 778  ICRLEESIAVMEDRRYSL------ERKADQLGSYLQEKQKAYSEYTIQEDEL 823
            I   E++ A+ E     L      ERK  Q    L+EK+ +Y  Y  + +EL
Sbjct: 1497 IQSQEDTTALKEVLSSVLKSVEERERKVQQEMYQLKEKKASYEYYRSKCEEL 1548


>UniRef50_Q9XZE3 Cluster: Myosin heavy chain; n=1; Amoeba proteus|Rep:
            Myosin heavy chain - Amoeba proteus (Amoeba)
          Length = 2138

 Score =  124 bits (299), Expect = 2e-26
 Identities = 259/1254 (20%), Positives = 502/1254 (40%), Gaps = 80/1254 (6%)

Query: 331  LEHLNCQIRQTNKELENKLATMGTE-SKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQL 389
            L  L  Q  ++ K+L+   A  G + S+     ++  S   S +S + T SK +     L
Sbjct: 942  LRDLKRQCDESEKKLKELEADAGKKKSEKAKQETEIASISASLESEKETNSKYQLQVRNL 1001

Query: 390  SSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLI 449
                  +  D      EIA L+     L+ +L D E    E D               L 
Sbjct: 1002 LRNLEEEKEDMARLDEEIANLQRFKDRLSLELDDLE---DELDEYTKVKQAAEKNISALN 1058

Query: 450  AQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAE 509
             QL+ E ++ +E  S     +   +     K+ E LK  L  EI      D  +  K+ +
Sbjct: 1059 DQLK-ETKRELETESAARGASEANNKKYQEKIGE-LKGNLQREIGSNTTMD--KNNKALQ 1114

Query: 510  EQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQ 569
              I++LND+ +  N N  K  SN +LK K      D  S + D + + +RLT E   L  
Sbjct: 1115 GNISELNDQTEDEN-NKKKTLSN-QLK-KVGDDLADVRSHIDDEHNQKLRLTNENTRLEA 1171

Query: 570  KV----AELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFD 625
             +     +L+E KG +     +    +    DV  +  + EN      K    L   K D
Sbjct: 1172 AIDDLKRQLDETKGKISKLEKEKQQLQKHLEDVTAQFEDAENKFSQLTKTNLKL---KAD 1228

Query: 626  LVQELHILQQKYDEVEDKLAD-ISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIEN 684
            L  EL   ++  D+   KL   +++L+SD+   E +     +  + L A KK     ++ 
Sbjct: 1229 L-DELQDNREGGDQAFQKLKKLVAKLESDKKMKEKEYEDERDLKNKLDAQKKLSQAELDG 1287

Query: 685  LKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQ 744
            LK   E++       E +++D+ N+L+       +L D+ E   A + S L  K    E 
Sbjct: 1288 LKNALEEMAKNRSREEKNRKDLENRLR-------ELEDQAEDGQAAR-SNLEKKFRGFED 1339

Query: 745  SKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGS 804
            +    Q  +D ++Q+ D+ +  + +   K +S +  L+ S+    + R   E K   L +
Sbjct: 1340 NLEDHQSQVD-EVQD-DVNV--LSAAKKKLESELEALKRSLDNEAEGRKVAEEKMKVLDT 1395

Query: 805  YLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQN 864
             L E Q A S    +   LV  +  + D    VE    + E+ +KEL K    L + N+ 
Sbjct: 1396 ELHELQLALSNAENKNTGLVRNVKKVQDE---VEDLNEQYENASKELSK----LDKGNKK 1448

Query: 865  LQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKK- 923
             +  L ++++H     E  +  D  E +    Q +L +L   L+ +  +  +L   KK+ 
Sbjct: 1449 TEAELKELRRHVQ---ESQSSLDAGELKLRHTQDELDELHHQLEDLEAKSSSLERSKKQL 1505

Query: 924  EIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNK 983
            +++  ++E   + E A R K    E+  K++E    L A+LQE +   E L    + L  
Sbjct: 1506 QLQVDDLEDTHEEELAARTKA---ERLVKDLE--ADL-AELQETRVESEPLMQAEKALKS 1559

Query: 984  MNLELID--KHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMS 1041
            + +EL+D  K   +Q         +  + + +   L  Q DE    L    + A+    +
Sbjct: 1560 LEVELVDLKKDADRQSQAFAKVENERRSALREYEDLQAQLDETSKNL-ANADRAKKKLNT 1618

Query: 1042 MVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLT 1101
             + +  SKL + +   +++E+ +++  K L  +K  +      V +++ +  + +   L 
Sbjct: 1619 DLDEQLSKLEKASNAQKSLEKRLKKAEKDLAAAKAASARAGGGVSDEELRRAQAELAALR 1678

Query: 1102 FEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQE---EEEFIQERSVLQ 1158
             + +  ++  +     ++ +  +  ++             L       E+E  + R  L+
Sbjct: 1679 DDADRERSNKLTAEKRVKNLQAEIEDLKEMLEDEKTSKEALNRNNKSLEQELEELREQLE 1738

Query: 1159 EQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVA 1218
             +   LN   +  + K +++  L  +L       +++  QLK++LE+   +  + L    
Sbjct: 1739 AEEEALNYLEEIKHKKDLEINELRKQLDAESEA-RDKFEQLKNELERDVADAKHNLEAEK 1797

Query: 1219 ELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSS 1278
            + R+       +   +  EL K      +    K E E +  L       E++ +++++ 
Sbjct: 1798 KSRTDAEREAKKAEAQYDEL-KHRSEASDRGKDKLEKERKRALKELRLLREKV-EAIEAE 1855

Query: 1279 TQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXX 1338
              E+       ++      +  D E   R   EK A      + LR ++ED K       
Sbjct: 1856 KDEQERLAWKFQEEVDALTEALDLEHKARVAHEKIA------KQLRVQLEDFKET-AEDA 1908

Query: 1339 XXXXXXXXXXXXDLRTENQSYK-QMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVND 1397
                        +L+ E +  K Q+ E+     N E A  K ++            R   
Sbjct: 1909 TRGKSRADQLTSELQAEIEDLKDQLDEEE--ERNRELANFKINNKSAIADLKKALDREIS 1966

Query: 1398 AEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKES 1457
            A   + E   QLE  ++E+  +  E  ++   R +     R+   E E     L     S
Sbjct: 1967 AREALEEAKRQLERDNNELRDQLDEERVS---RGNSERAARKSFAELEDTNARLNALNAS 2023

Query: 1458 ELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVA 1517
               + + K    A++  + ++ +++++ +  E+     +    L  +V  L   L +E  
Sbjct: 2024 IGKLEKAKRRAEADYRASKKQLADLQKKEATED-----SLRAQLEAEVRRLKSRLVDEQD 2078

Query: 1518 KTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQ 1571
            +  + ++     E+EI  L DE+  L + +  + ++ ++    AS+ KQ  +E+
Sbjct: 2079 RAADAESDRRRAEVEINKLRDEVRVLSDELERAKAEARQ----ASEDKQELEER 2128



 Score =  113 bits (272), Expect = 4e-23
 Identities = 241/1245 (19%), Positives = 499/1245 (40%), Gaps = 120/1245 (9%)

Query: 145  THLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXX 204
            T L N++ +K++ L +L+  +   ++ + DL+ + +E     E K K             
Sbjct: 915  TTLRNSMSKKESELDLLRGDISTGDSKLRDLKRQCDES----EKKLKELEADAGKKKSEK 970

Query: 205  XXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAAR 264
                         +   +E      ++++ + + LL+++E +   ++ L+E    L+  +
Sbjct: 971  AKQETEIASISASLESEKET----NSKYQLQVRNLLRNLEEEKEDMARLDEEIANLQRFK 1026

Query: 265  FEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTEL 324
              +SLE   L  EL++              L  Q  E   E +TE   +G+ E  N    
Sbjct: 1027 DRLSLELDDLEDELDEYTKVKQAAEKNISALNDQLKETKRELETESAARGASEANNKKYQ 1086

Query: 325  TKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKS 384
             K  EL  +L  +I       +N  A  G  S+       + +    +K+  N   K+  
Sbjct: 1087 EKIGELKGNLQREIGSNTTMDKNNKALQGNISELNDQTEDENN---KKKTLSNQLKKVGD 1143

Query: 385  PWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXG 444
              + + S   ++   K    NE  +LE  I  L + L + +                  G
Sbjct: 1144 DLADVRSHIDDEHNQKLRLTNENTRLEAAIDDLKRQLDETK------------------G 1185

Query: 445  KDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEK 504
            K + + + + + Q+H+E  +        +  +++ K   +LK +L DE++D         
Sbjct: 1186 KISKLEKEKQQLQKHLEDVTAQFEDAENK-FSQLTKTNLKLKADL-DELQD--------- 1234

Query: 505  LKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEEL 564
             +   +Q  Q   ++ A  ++  K+K       + ++  +D   K+S +  E+  L   L
Sbjct: 1235 NREGGDQAFQKLKKLVAKLESDKKMKEKEYEDERDLKNKLDAQKKLSQA--ELDGLKNAL 1292

Query: 565  HHLSQKVAELEEEKGNLQLHLVDY----DSGRMIESDVYKKMIEMENLAETRLKAISLLE 620
              +++  +  E+ + +L+  L +     + G+   S++ KK    E+  E         +
Sbjct: 1293 EEMAKNRSREEKNRKDLENRLRELEDQAEDGQAARSNLEKKFRGFEDNLEDH-------Q 1345

Query: 621  SQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELAL 680
            SQ  ++  ++++L     ++E +L  + +   ++  +E + V  EE++  L     EL L
Sbjct: 1346 SQVDEVQDDVNVLSAAKKKLESELEALKRSLDNE--AEGRKV-AEEKMKVLDTELHELQL 1402

Query: 681  VIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKIN 740
             + N +     L   +K ++++ ED+  + +N  +E +   DK  K +  ++ EL   + 
Sbjct: 1403 ALSNAENKNTGLVRNVKKVQDEVEDLNEQYENASKE-LSKLDKGNKKTEAELKELRRHVQ 1461

Query: 741  HEEQSKIQTQFGI---DAKIQERDLYIENIESELSKYKSRICRLEESIAVMED------- 790
              + S    +  +     ++ E    +E++E++ S  +    +L+  +  +ED       
Sbjct: 1462 ESQSSLDAGELKLRHTQDELDELHHQLEDLEAKSSSLERSKKQLQLQVDDLEDTHEEELA 1521

Query: 791  RRYSLERKADQLGSYLQEKQ--KAYSEYTIQEDELVNRLAV-LMDHDRVVEKQLLEIEHE 847
             R   ER    L + L E Q  +  SE  +Q ++ +  L V L+D  +  ++Q       
Sbjct: 1522 ARTKAERLVKDLEADLAELQETRVESEPLMQAEKALKSLEVELVDLKKDADRQ----SQA 1577

Query: 848  NKELQKKNQILLEENQNLQISLSDMQQHY-NA-LVEKANRTDLAE--SESTKYQTQLRDL 903
              +++ + +  L E ++LQ  L +  ++  NA   +K   TDL E  S+  K     + L
Sbjct: 1578 FAKVENERRSALREYEDLQAQLDETSKNLANADRAKKKLNTDLDEQLSKLEKASNAQKSL 1637

Query: 904  ESNLKRITHEHQTLIVQKKKE---IEDLEIEFNTQIESAIRDKKVLNEKYEKNIE-YVTQ 959
            E  LK+   +         +    + D E+       +A+RD        +   E  V  
Sbjct: 1638 EKRLKKAEKDLAAAKAASARAGGGVSDEELRRAQAELAALRDDADRERSNKLTAEKRVKN 1697

Query: 960  LEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQ-KQQTQSPDYTEQYINEIN-----K 1013
            L+A++++ K  +E+   + E LN+ N  L  +  + ++Q ++ +    Y+ EI      +
Sbjct: 1698 LQAEIEDLKEMLEDEKTSKEALNRNNKSLEQELEELREQLEAEEEALNYLEEIKHKKDLE 1757

Query: 1014 LNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLD 1073
            +N L KQ D E  A   K    +      V+D +  L        + E E ++   Q  +
Sbjct: 1758 INELRKQLDAESEA-RDKFEQLKNELERDVADAKHNLEAEKKSRTDAEREAKKAEAQYDE 1816

Query: 1074 SKQHNEE----LQILVREQDDQIKE---LKETKLTFEMNIPKTEGMI--ISSTIEPMSDD 1124
             K  +E        L +E+   +KE   L+E     E    + E +       ++ +++ 
Sbjct: 1817 LKHRSEASDRGKDKLEKERKRALKELRLLREKVEAIEAEKDEQERLAWKFQEEVDALTEA 1876

Query: 1125 ANNVDXXXXXXXXXXXXLKVQEE------EEFIQERSVLQEQSAKLNTELQECYTKIIQL 1178
             +               L+VQ E      E+  + +S   + +++L  E+++   ++ + 
Sbjct: 1877 LDLEHKARVAHEKIAKQLRVQLEDFKETAEDATRGKSRADQLTSELQAEIEDLKDQLDEE 1936

Query: 1179 ETLNTELTGHDVVNQEQINQLKSKLE--------------QLNTENDNLLSTVAELRSS- 1223
            E  N EL    + N+  I  LK  L+              QL  +N+ L   + E R S 
Sbjct: 1937 EERNRELANFKINNKSAIADLKKALDREISAREALEEAKRQLERDNNELRDQLDEERVSR 1996

Query: 1224 -ISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEE 1282
              S    ++ F   E     L    A   K E   R   + + +  +QL D  +    E+
Sbjct: 1997 GNSERAARKSFAELEDTNARLNALNASIGKLEKAKRRAEADYRASKKQLADLQKKEATED 2056

Query: 1283 TNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEI 1327
            + +     +V  L+++L D+++   + +        +I  LR E+
Sbjct: 2057 SLRAQLEAEVRRLKSRLVDEQDRAADAESDRRRAEVEINKLRDEV 2101



 Score =  107 bits (256), Expect = 3e-21
 Identities = 183/996 (18%), Positives = 410/996 (41%), Gaps = 95/996 (9%)

Query: 654  QVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNY 713
            +V  +IK V  + ++      K      +  ++ +KE+    +K+LE      M  L+  
Sbjct: 837  KVKKDIKRVDWDAELSKADLDKNAALKELARIQAEKERTEFQLKELEGTIGSFMENLRGA 896

Query: 714  IQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSK 773
             ++  ++ DK   +  E+ +  L     +++S++    G    I   D  + +++ +  +
Sbjct: 897  EKQLHEIQDKYHALDEERTT--LRNSMSKKESELDLLRG---DISTGDSKLRDLKRQCDE 951

Query: 774  YKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRL------ 827
             + ++  LE      +  +   E +   + + L+ +++  S+Y +Q   L+  L      
Sbjct: 952  SEKKLKELEADAGKKKSEKAKQETEIASISASLESEKETNSKYQLQVRNLLRNLEEEKED 1011

Query: 828  AVLMDHD-----RVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEK 882
               +D +     R  ++  LE++    EL +  ++     +N+      +++    L  +
Sbjct: 1012 MARLDEEIANLQRFKDRLSLELDDLEDELDEYTKVKQAAEKNISALNDQLKETKRELETE 1071

Query: 883  ANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRD 942
            +     +E+ + KYQ ++ +L+ NL+R    + T+  +  K ++    E N Q E     
Sbjct: 1072 SAARGASEANNKKYQEKIGELKGNLQREIGSNTTM-DKNNKALQGNISELNDQTEDENNK 1130

Query: 943  KKVLNEKYEK---NIEYV------------------TQLEAQLQEYKNNIENLNMNVEEL 981
            KK L+ + +K   ++  V                  T+LEA + + K  ++     + +L
Sbjct: 1131 KKTLSNQLKKVGDDLADVRSHIDDEHNQKLRLTNENTRLEAAIDDLKRQLDETKGKISKL 1190

Query: 982  NKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLK-----------------QKDEE 1024
             K   +L  KH++    Q  D  E   +++ K N  LK                 QK ++
Sbjct: 1191 EKEKQQL-QKHLEDVTAQFED-AENKFSQLTKTNLKLKADLDELQDNREGGDQAFQKLKK 1248

Query: 1025 IIALNQKINNAQVSYMSMVSDYESKL-AQ---FTTKLENMEEEMQRVSKQLLDSKQHNEE 1080
            ++A  +     +        D ++KL AQ      +L+ ++  ++ ++K     +++ ++
Sbjct: 1249 LVAKLESDKKMKEKEYEDERDLKNKLDAQKKLSQAELDGLKNALEEMAKNRSREEKNRKD 1308

Query: 1081 LQILVREQDDQIKELKETKLTFEMNIPKTEGMI--ISSTIEPMSDDANNVDXXXXXXXXX 1138
            L+  +RE +DQ ++ +  +   E      E  +    S ++ + DD N +          
Sbjct: 1309 LENRLRELEDQAEDGQAARSNLEKKFRGFEDNLEDHQSQVDEVQDDVNVLSAAKKKLESE 1368

Query: 1139 XXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQ 1198
               LK   + E  + R V +E+   L+TEL E    +   E  NT L          + +
Sbjct: 1369 LEALKRSLDNE-AEGRKVAEEKMKVLDTELHELQLALSNAENKNTGLV-------RNVKK 1420

Query: 1199 LKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELR 1258
            ++ ++E LN + +N     ++  S +     +   E+ EL ++H+ + ++     E +LR
Sbjct: 1421 VQDEVEDLNEQYEN----ASKELSKLDKGNKKTEAELKEL-RRHVQESQSSLDAGELKLR 1475

Query: 1259 VQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVIN 1318
                  +  + QL D    S+  E +K    +Q+    + L+D  E     + K   ++ 
Sbjct: 1476 HTQDELDELHHQLEDLEAKSSSLERSK----KQLQLQVDDLEDTHEEELAARTKAERLVK 1531

Query: 1319 QIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLK 1378
             +E   +E+++ +V                   +  +  + +Q Q  + +  NE  + L+
Sbjct: 1532 DLEADLAELQETRVESEPLMQAEKALKSLEVELVDLKKDADRQSQAFAKVE-NERRSALR 1590

Query: 1379 KSSXXXXXXXXXXXXRVNDAEAKV---LELTHQL-ELKDSEIYQKTHEYTITLTQRNDEF 1434
            +                N   AK     +L  QL +L+ +   QK+ E  +   +++   
Sbjct: 1591 EYEDLQAQLDETSKNLANADRAKKKLNTDLDEQLSKLEKASNAQKSLEKRLKKAEKDLAA 1650

Query: 1435 ENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVK 1494
                          E+L    ++ELA LR       ++  T +K  +  + + IE+L   
Sbjct: 1651 AKAASARAGGGVSDEELR-RAQAELAALRDDADRERSNKLTAEKRVKNLQAE-IEDLKEM 1708

Query: 1495 ITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKI 1554
            + +  +  + +   NK+LE+E+    E++  LE +E E +   +EI + +++     +++
Sbjct: 1709 LEDEKTSKEALNRNNKSLEQEL---EELREQLEAEE-EALNYLEEIKHKKDL---EINEL 1761

Query: 1555 QKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELD 1590
            +K +   S+ +  + EQL N + +++ DA    E +
Sbjct: 1762 RKQLDAESEARD-KFEQLKNELERDVADAKHNLEAE 1796


>UniRef50_Q24GP7 Cluster: Putative uncharacterized protein; n=2;
            cellular organisms|Rep: Putative uncharacterized protein
            - Tetrahymena thermophila SB210
          Length = 2929

 Score =  124 bits (299), Expect = 2e-26
 Identities = 272/1356 (20%), Positives = 579/1356 (42%), Gaps = 141/1356 (10%)

Query: 302  PSC---EEKTEIEEK-GSLEIANMTELTKKIELLEHLNCQIRQTNKEL--ENKLATMGTE 355
            P C   EEK+ ++ K   +E+    E   K  + + +N     TNK     N +AT    
Sbjct: 249  PDCIIVEEKSTLKPKQAEVEMCIEIEANPKDLIQQKMN---NSTNKSYFSNNSIAT---- 301

Query: 356  SKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQ-LSSETLNQDTDKKINKNE---IAKLE 411
             K + S  K  S + S  S  N  S  K       ++ T NQ T K   +NE   I +LE
Sbjct: 302  PKHLESSLKMDSSIKSNTSSINKLSSNKEENKNGPNTITNNQTTSKIFQENEKQGIIQLE 361

Query: 412  MVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTN 471
              +Q  N  + D+  V                 K   I     +  Q  + P  I    +
Sbjct: 362  NNLQKSNCQIKDQTNVNDLIANQSINSENLQSVKSLEIQNQGKQEDQFQDKPKQISDNNS 421

Query: 472  TEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKL-KSAEEQITQLNDEIDAA---NKNMI 527
            T   N     + Q  Q+ ND +K      +IE +  S+E  ++Q+N + ++    ++ + 
Sbjct: 422  TSINNYDLSSKFQQNQKQNDILK------IIENIPSSSESDLSQINSQPNSQQTQDQQLF 475

Query: 528  KVKS------NHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNL 581
            K ++      NH+  + Q ++  D+         +         + +Q+   + EEK N 
Sbjct: 476  KQETKAIYDINHQSPILQQKQIQDDIISNKQFKNDQNNQNNGDKYETQEDQFVFEEK-NP 534

Query: 582  QLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKY-DEV 640
            Q  L +     +I  D  +K+  ++N      + ++   +QK++L Q     Q K  DE 
Sbjct: 535  QNELNETKQQNIISEDNLQKLNSIQNSDLNLSQNLNKNSAQKYELNQTAVESQLKIIDED 594

Query: 641  EDKLADISQLQ-----SDQVCSEI-KSVHLEEQIDALSASKKELA----LVIENLKLDKE 690
            +    D+++ Q     S  +  EI K+ H E++ +A   +++EL     LV EN  + K+
Sbjct: 595  QYVNKDLNEQQQIIQTSQNIDEEINKTNHFEQESNAQQNNQEELKNESQLVQEN-NITKQ 653

Query: 691  QLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQ 750
             +      L++++    +++  YIQ+      +++ +S +K  E     +  +Q+  QTQ
Sbjct: 654  IISNQFSQLQSNQVKSTSQISQYIQQ------EIQPLSLQKSEEQ----SSFQQNLTQTQ 703

Query: 751  FGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQ-LGSYLQEK 809
               +    E++   ++ + +LS+    + R+EE     E+    +E +  Q   + L EK
Sbjct: 704  QNQNEISLEKESSKQSAQ-KLSQLLDTLDRMEEE----EENEQKIETETIQNQNNILNEK 758

Query: 810  QKAYSEYTIQEDELVNRLAVLMDH--------DRVVEKQLLEIEHENKELQKKNQILLEE 861
            +   ++   +++E +   A  MD+        D ++  Q +     N  L+ KNQ+ +EE
Sbjct: 759  EITNAQMDEEKEEEIRGQANQMDNLFQNNPNQDDLLIDQQISNNQTNISLESKNQVQIEE 818

Query: 862  NQ-----NLQISLSDMQQHYNALVEK---ANRTDLAESES-TKYQTQLRDLESNLKRIT- 911
            +Q     +      D +Q  N  VEK   +N++ L + +S TK   Q+ + E   K I  
Sbjct: 819  SQMKPETSQSFKQEDTEQD-NKSVEKLIASNKSSLQKDQSLTKVINQIEECEKLDKIIDE 877

Query: 912  HEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNI 971
            ++ +      +++I    IE N   ++++      N+   +  + ++ + +Q++E++  +
Sbjct: 878  NDEENQSKTNQQQIITESIEKNQNEKNSMEKFNDSNKSSLQKDKSLSSILSQIEEFEK-M 936

Query: 972  ENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNA-LLKQKDEEI--IAL 1028
            E+ +   EE+    ++ +D        Q+    ++   E++K N  LL+Q+  +   + +
Sbjct: 937  EDEDEK-EEIQVSKIDQLDHFKNNNLLQNIQMDQEKEIEMSKNNQQLLEQQSTQNNQLDI 995

Query: 1029 NQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQ 1088
            N+K +N         ++Y  ++ Q    L++ +EE+++  +Q     Q+N++L   V+E 
Sbjct: 996  NEKTSNQ--------NEYNQQIDQ--NNLQSQKEELKQQDQQTFIENQNNQQLNE-VQES 1044

Query: 1089 DDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEE 1148
            + Q       ++  EMN+ K    +I++    +       +            +  QE+ 
Sbjct: 1045 NSQ------QEIQIEMNL-KDNNQVINNLQNDIQPKDEQSEIKTCQIQDNDKEINQQEQH 1097

Query: 1149 EFIQE--RSVLQEQSAKLNTELQEC-YTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQ 1205
            +   +  + +    S+  + + QE  + +    + LN +     +   EQ N +    + 
Sbjct: 1098 QINSQLLKIIDDSSSSSQSNDSQEVNFQQNEHQQILNIQNENQQLDQIEQENLINDSDQL 1157

Query: 1206 LNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFE 1265
            +   ND + +T  +    I +    +  +  E   Q    ++ +  +T+++   Q S  +
Sbjct: 1158 VEVSNDKVQNTFEQQNEQIQNINHNQLNQFEEYAIQDQNNKQIENIETQNQ---QNSLVQ 1214

Query: 1266 SKYEQLLD-SVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILR 1324
               EQ+ + +V  +   + N +   EQ+   +NK Q+  E L + Q     +  Q++IL 
Sbjct: 1215 ENLEQITELNVNINQINQHNLLKQTEQIE--ENKEQNDIEQL-DFQNDEQQIYTQVDILS 1271

Query: 1325 SEIEDE-KVAFXXXXXXXXXXXXXXXXDLRTE-------------NQSYKQMQEQSILNI 1370
             E+  E +                   +L+ +              QS  + ++QSIL +
Sbjct: 1272 KEVASENQQQSNEKQQIQVEEKEQQITELKDQLPEINKHEIIEVNQQSIHEQEQQSIL-M 1330

Query: 1371 NEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQR 1430
             ++   ++               +V DA+ ++ EL  Q++++D +I  +     IT  Q+
Sbjct: 1331 QKQQQYVEAKEQQTTQSEVNRYLQV-DAKQQISELKQQIQVEDEQIVDQVSSQ-IT-EQK 1387

Query: 1431 NDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIER--VKLI 1488
            N +   +++Q   + ++I+++  E +  ++I + K  +N   YE  Q E EIE+   ++ 
Sbjct: 1388 NQQQSQIQEQY--HVEQIQNIV-ENDQSISIDQ-KQQQNCV-YEVQQLEQEIEQQGKEID 1442

Query: 1489 EELNVKIT-ESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMV 1547
            E+   +++ +S+ LN Q+ E  K L++   + +  Q  +  Q  +I    +E+   Q ++
Sbjct: 1443 EQQQQQVSQQSIQLNTQIQEEEKLLQQSHIEEDLQQKLIVEQNQQIFQCVNEVQQQQKVI 1502

Query: 1548 -RASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLD 1582
                   +++ +   S  ++ + E+      ++L+D
Sbjct: 1503 DDKQQESVEQSLHEQSAQQREQKEEFSEPSKQQLID 1538



 Score =  119 bits (287), Expect = 6e-25
 Identities = 244/1314 (18%), Positives = 546/1314 (41%), Gaps = 111/1314 (8%)

Query: 297  KQSIEPSCEEKTEIEEKGSLEIA-NMTELTKKIELLEHLNCQIRQTNKELENKLATMGTE 355
            ++ +E   ++  E+++   +++     +  KK E    L+  I+  N   ++ + T  + 
Sbjct: 39   REKLEQQLKKAKELQKLAQIDLEITKKDSVKKDEPAPTLSTNIQ--NPTAQSSVTTTPSS 96

Query: 356  SKA-----VSSPSKKGSPLISRKSGRNTASKMKSPWSQLSS--ETLNQDTDKKINKNEIA 408
            ++      VSS S + S ++ R   +N  S + +P S  S+   TL   T+ K +    +
Sbjct: 97   NQVPSVSMVSSFSSRFSSILQRD--QNKTSLINTPLSTTSTAPSTLPAITENKFSAIS-S 153

Query: 409  KLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXX------GKDTLIAQLQLEHQQHMEG 462
            +L  + +SLN+ L + E  +  +                   K ++   L LE+ +    
Sbjct: 154  RLSQLRESLNQTLSNSEIKLPSQPVSQNNRETKSEIRDFSDNKQSINKSLLLENNKQTHD 213

Query: 463  PSLIHVGT-------NTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQL 515
             S+  + +       ++ D N++  +Q +  ++ N +   V  K  + K K AE    ++
Sbjct: 214  SSITSIISKIKSNIQSSTDTNQVGNLQIKKNEDNNPDCIIVEEKSTL-KPKQAE---VEM 269

Query: 516  NDEIDAANKNMIKVKSNHKLKLKQMQK-TIDNFSKVSDSNKEIVRLTEELHHLSQKVAEL 574
              EI+A  K++I+ K N+          +I     +  S K    +      +++  +  
Sbjct: 270  CIEIEANPKDLIQQKMNNSTNKSYFSNNSIATPKHLESSLKMDSSIKSNTSSINKLSSNK 329

Query: 575  EEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAE---------TRLKAISLLESQKFD 625
            EE K        +  + ++ + +  + +I++EN  +         T +  +   +S   +
Sbjct: 330  EENKNGPNTITNNQTTSKIFQENEKQGIIQLENNLQKSNCQIKDQTNVNDLIANQSINSE 389

Query: 626  LVQELHILQ-QKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIEN 684
             +Q +  L+ Q   + ED+  D  +  SD   + I +  L  +    +  + ++  +IEN
Sbjct: 390  NLQSVKSLEIQNQGKQEDQFQDKPKQISDNNSTSINNYDLSSKFQQ-NQKQNDILKIIEN 448

Query: 685  LKLDKEQLYGTIKDLENDKEDIMNKL-QNYIQENMDLTDKLEKMSAEKISELLAKINHEE 743
            +    E     I    N ++    +L +   +   D+  +   +  ++I + +      +
Sbjct: 449  IPSSSESDLSQINSQPNSQQTQDQQLFKQETKAIYDINHQSPILQQKQIQDDIISNKQFK 508

Query: 744  QSKIQTQFGIDAKIQERDLYIE--NIESELSKYKSRICRLEESIAVMEDRRYSLERKADQ 801
              +     G   + QE     E  N ++EL++ K +    E+++  +     S++     
Sbjct: 509  NDQNNQNNGDKYETQEDQFVFEEKNPQNELNETKQQNIISEDNLQKLN----SIQNSDLN 564

Query: 802  LGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLE-------IEHENKELQKK 854
            L   L +      +Y + +  + ++L ++ D D+ V K L E        ++ ++E+ K 
Sbjct: 565  LSQNLNKNSA--QKYELNQTAVESQLKII-DEDQYVNKDLNEQQQIIQTSQNIDEEINKT 621

Query: 855  NQILLEENQNLQISLSDMQQHYNALVEKANRT-DLAESESTKYQT-QLRDLESNLKRITH 912
            N    E+  N Q +  +  ++ + LV++ N T  +  ++ ++ Q+ Q++      + I  
Sbjct: 622  NHF--EQESNAQQNNQEELKNESQLVQENNITKQIISNQFSQLQSNQVKSTSQISQYIQQ 679

Query: 913  EHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIE 972
            E Q L +QK +E    +    TQ +    +  +  E  +++ + ++QL   L   +   E
Sbjct: 680  EIQPLSLQKSEEQSSFQQNL-TQTQQNQNEISLEKESSKQSAQKLSQLLDTLDRMEEEEE 738

Query: 973  N-LNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQK-DEEIIALNQ 1030
            N   +  E +   N  L +K +   Q    +  E+   + N+++ L +   +++ + ++Q
Sbjct: 739  NEQKIETETIQNQNNILNEKEITNAQMDE-EKEEEIRGQANQMDNLFQNNPNQDDLLIDQ 797

Query: 1031 KINNAQVSYM----SMVSDYESKLAQFTT---KLENMEEEMQRVSKQLLDSKQHNEELQI 1083
            +I+N Q +      + V   ES++   T+   K E+ E++ + V K +  +K   ++ Q 
Sbjct: 798  QISNNQTNISLESKNQVQIEESQMKPETSQSFKQEDTEQDNKSVEKLIASNKSSLQKDQS 857

Query: 1084 LVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLK 1143
            L +  + QI+E ++     + N  + +       I   S + N  +              
Sbjct: 858  LTKVIN-QIEECEKLDKIIDENDEENQSKTNQQQIITESIEKNQNEKNSMEKFNDSNKSS 916

Query: 1144 VQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKL 1203
            +Q+++      S ++E   K+  E ++   ++ +++ L+     ++++   Q++Q K   
Sbjct: 917  LQKDKSLSSILSQIEEFE-KMEDEDEKEEIQVSKIDQLD-HFKNNNLLQNIQMDQEKEI- 973

Query: 1204 EQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSA 1263
             +++  N  LL   +   + +   ++++     E + Q + Q     QK E + + Q + 
Sbjct: 974  -EMSKNNQQLLEQQSTQNNQLD--INEKTSNQNE-YNQQIDQNNLQSQKEELKQQDQQTF 1029

Query: 1264 FESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEIL 1323
             E++  Q L+ VQ S  +         Q   ++  L+D  + + NLQ        Q EI 
Sbjct: 1030 IENQNNQQLNEVQESNSQ---------QEIQIEMNLKDNNQVINNLQNDIQPKDEQSEIK 1080

Query: 1324 RSEIED-EKVAFXXXXXXXXXXXXXXXXDLRTENQS-------YKQMQEQSILNINEENA 1375
              +I+D +K                   D  + +QS       ++Q + Q ILNI  EN 
Sbjct: 1081 TCQIQDNDKEINQQEQHQINSQLLKIIDDSSSSSQSNDSQEVNFQQNEHQQILNIQNENQ 1140

Query: 1376 QLKKSSXXXXXXXXXXXXRV-NDAEAKVLE-LTHQLELKDSEIYQKTHEYTITLTQRNDE 1433
            QL +               V ND      E    Q++  +     +  EY I   Q N +
Sbjct: 1141 QLDQIEQENLINDSDQLVEVSNDKVQNTFEQQNEQIQNINHNQLNQFEEYAIQ-DQNNKQ 1199

Query: 1434 FENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNV 1493
             EN     +E + +   L  E   ++  L + +++  N +  +++  +IE  K  E+ ++
Sbjct: 1200 IEN-----IETQNQQNSLVQENLEQITELNVNINQ-INQHNLLKQTEQIEENK--EQNDI 1251

Query: 1494 KITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMV 1547
            +  +  +  +Q+      L +EVA  N+ Q+  E Q+I++     +IT L++ +
Sbjct: 1252 EQLDFQNDEQQIYTQVDILSKEVASENQQQSN-EKQQIQVEEKEQQITELKDQL 1304



 Score =   99 bits (238), Expect = 5e-19
 Identities = 196/1043 (18%), Positives = 441/1043 (42%), Gaps = 100/1043 (9%)

Query: 298  QSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESK 357
            Q+I+    +    E++ + +  N  EL  + +L++  N   +  + +     +     + 
Sbjct: 612  QNIDEEINKTNHFEQESNAQQNNQEELKNESQLVQENNITKQIISNQFSQLQSNQVKSTS 671

Query: 358  AVSSPSKKG-SPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQS 416
             +S   ++   PL  +KS   ++ +     +Q +   ++   +K+ +K    KL  ++ +
Sbjct: 672  QISQYIQQEIQPLSLQKSEEQSSFQQNLTQTQQNQNEIS--LEKESSKQSAQKLSQLLDT 729

Query: 417  LNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPS--LIHVGTNTED 474
            L++   ++E     +             K+   AQ+  E ++ + G +  + ++  N  +
Sbjct: 730  LDRMEEEEENEQKIETETIQNQNNILNEKEITNAQMDEEKEEEIRGQANQMDNLFQNNPN 789

Query: 475  VNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHK 534
             +++   Q+    + N  ++  N   + E     E   +   ++ +  NK++ K+ +++K
Sbjct: 790  QDDLLIDQQISNNQTNISLESKNQVQIEESQMKPETSQSFKQEDTEQDNKSVEKLIASNK 849

Query: 535  LKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMI 594
              L++ Q    + +KV +  +E     E+L  +  +  E  + K N Q  + +       
Sbjct: 850  SSLQKDQ----SLTKVINQIEEC----EKLDKIIDENDEENQSKTNQQQIITESIEKNQN 901

Query: 595  ESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQ 654
            E +  +K  +    +  + K++S + SQ    ++E   ++ + ++ E +++ I QL   +
Sbjct: 902  EKNSMEKFNDSNKSSLQKDKSLSSILSQ----IEEFEKMEDEDEKEEIQVSKIDQLDHFK 957

Query: 655  VCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYI 714
              + ++++ ++++ + +  SK    L +E       QL     D+ N+K    N+    I
Sbjct: 958  NNNLLQNIQMDQEKE-IEMSKNNQQL-LEQQSTQNNQL-----DI-NEKTSNQNEYNQQI 1009

Query: 715  QENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKY 774
             +N +L  + E++  +     +   N+++ +++Q +     +IQ        IE  L   
Sbjct: 1010 DQN-NLQSQKEELKQQDQQTFIENQNNQQLNEVQ-ESNSQQEIQ--------IEMNLKDN 1059

Query: 775  KSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHD 834
               I  L+  I   +++    E K  Q+    Q+  K  ++   QE   +N   + +  D
Sbjct: 1060 NQVINNLQNDIQPKDEQS---EIKTCQI----QDNDKEINQ---QEQHQINSQLLKIIDD 1109

Query: 835  RVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESEST 894
                 Q  + +  N +  +  QIL  +N+N Q+   + +   N      +   L E  + 
Sbjct: 1110 SSSSSQSNDSQEVNFQQNEHQQILNIQNENQQLDQIEQENLIN------DSDQLVEVSND 1163

Query: 895  KYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNI 954
            K Q         ++ I H                  + N   E AI+D+   N K  +NI
Sbjct: 1164 KVQNTFEQQNEQIQNINHN-----------------QLNQFEEYAIQDQ---NNKQIENI 1203

Query: 955  EYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKL 1014
            E   Q  + +QE    I  LN+N+ ++N+ NL    + +++ + Q+      + N+  ++
Sbjct: 1204 ETQNQQNSLVQENLEQITELNVNINQINQHNLLKQTEQIEENKEQNDIEQLDFQNDEQQI 1263

Query: 1015 NALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKL-ENMEEEMQRVSKQLLD 1073
               +    +E+ + NQ+ +N +      V + E ++ +   +L E  + E+  V++Q + 
Sbjct: 1264 YTQVDILSKEVASENQQQSNEK--QQIQVEEKEQQITELKDQLPEINKHEIIEVNQQSI- 1320

Query: 1074 SKQHNEELQILVREQDDQIKELKETKLT-FEMN--IPKTEGMIISSTIEPMS-DDANNVD 1129
               H +E Q ++ ++  Q  E KE + T  E+N  +       IS   + +  +D   VD
Sbjct: 1321 ---HEQEQQSILMQKQQQYVEAKEQQTTQSEVNRYLQVDAKQQISELKQQIQVEDEQIVD 1377

Query: 1130 XXXXXXXXXXXXLKVQEEEEFIQER---SVLQEQSAKLNTELQE-CYTKIIQLETLNTEL 1185
                         + Q +E++  E+    V  +QS  ++ + Q+ C  ++ QLE    E 
Sbjct: 1378 QVSSQITEQKNQQQSQIQEQYHVEQIQNIVENDQSISIDQKQQQNCVYEVQQLEQ-EIEQ 1436

Query: 1186 TGHDVVNQEQINQLKSKLEQLNT---ENDNLL--STVAE-LRSSISSAVDQRGFEIAELW 1239
             G ++  Q+Q  Q+  +  QLNT   E + LL  S + E L+  +    +Q+ F+     
Sbjct: 1437 QGKEIDEQQQ-QQVSQQSIQLNTQIQEEEKLLQQSHIEEDLQQKLIVEQNQQIFQCVNEV 1495

Query: 1240 KQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKL 1299
            +Q   Q+  D ++ E    V+ S  E   +Q  +  +  ++    +++  +    +Q + 
Sbjct: 1496 QQQ--QKVIDDKQQE---SVEQSLHEQSAQQ-REQKEEFSEPSKQQLIDQQASQKIQGEE 1549

Query: 1300 QDKEEHLRNLQEKYADVINQIEI 1322
            + ++    +  E   D  NQ+EI
Sbjct: 1550 KQQKIEENDKSELVIDTSNQLEI 1572



 Score = 91.5 bits (217), Expect = 2e-16
 Identities = 194/982 (19%), Positives = 435/982 (44%), Gaps = 111/982 (11%)

Query: 389  LSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTL 448
            L +  ++Q+ + +++KN    LE   QS   + +D    I+EK T           ++ L
Sbjct: 962  LQNIQMDQEKEIEMSKNNQQLLEQ--QSTQNNQLD----INEK-TSNQNEYNQQIDQNNL 1014

Query: 449  IAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVN--VKDLIEKLK 506
              Q Q E  +  +  + I    N + +NE+ +   Q + ++   +KD N  + +L   ++
Sbjct: 1015 --QSQKEELKQQDQQTFIE-NQNNQQLNEVQESNSQQEIQIEMNLKDNNQVINNLQNDIQ 1071

Query: 507  SAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSN-KEIVRLTEELH 565
              +EQ      +I   +K  I  +  H++   Q+ K ID+ S  S SN  + V   +  H
Sbjct: 1072 PKDEQSEIKTCQIQDNDKE-INQQEQHQIN-SQLLKIIDDSSSSSQSNDSQEVNFQQNEH 1129

Query: 566  HLSQKVAELEEEKGNLQLHLVDYDSGRMIE--SDVYKKMIE-----MENLAETRLKAIS- 617
                 +    ++   ++   +  DS +++E  +D  +   E     ++N+   +L     
Sbjct: 1130 QQILNIQNENQQLDQIEQENLINDSDQLVEVSNDKVQNTFEQQNEQIQNINHNQLNQFEE 1189

Query: 618  -LLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKK 676
              ++ Q    ++ +    Q+   V++ L  I++L  +   ++I   +L +Q + +  +K+
Sbjct: 1190 YAIQDQNNKQIENIETQNQQNSLVQENLEQITELNVN--INQINQHNLLKQTEQIEENKE 1247

Query: 677  ELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELL 736
            +  +   + + D++Q+Y  + D+ + +    N+ Q+  ++ + + +K ++++  ++ + L
Sbjct: 1248 QNDIEQLDFQNDEQQIYTQV-DILSKEVASENQQQSNEKQQIQVEEKEQQIT--ELKDQL 1304

Query: 737  AKINHEE-----QSKIQTQFGIDAKIQERDLYIE-----NIESELSKY-----KSRICRL 781
             +IN  E     Q  I  Q      +Q++  Y+E       +SE+++Y     K +I  L
Sbjct: 1305 PEINKHEIIEVNQQSIHEQEQQSILMQKQQQYVEAKEQQTTQSEVNRYLQVDAKQQISEL 1364

Query: 782  EESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQL 841
            ++ I V ED     E+  DQ+ S + E QK   +  IQE   V ++  ++++D+ +    
Sbjct: 1365 KQQIQV-ED-----EQIVDQVSSQITE-QKNQQQSQIQEQYHVEQIQNIVENDQSISIDQ 1417

Query: 842  LEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLR 901
             + ++   E+Q+  Q +  E Q  +I     QQ     ++    T + E E    Q+ + 
Sbjct: 1418 KQQQNCVYEVQQLEQEI--EQQGKEIDEQQQQQVSQQSIQL--NTQIQEEEKLLQQSHIE 1473

Query: 902  DLESNLKRITHEHQTL------IVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIE 955
            + +   K I  ++Q +      + Q++K I+D + E    +E ++ ++     + ++   
Sbjct: 1474 E-DLQQKLIVEQNQQIFQCVNEVQQQQKVIDDKQQE---SVEQSLHEQSAQQREQKEEFS 1529

Query: 956  YVT--QLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINK 1013
              +  QL  Q    K   E     +EE +K  L +ID   Q +  +    T    ++ + 
Sbjct: 1530 EPSKQQLIDQQASQKIQGEEKQQKIEENDKSEL-VIDTSNQLEIQEEKQVTSIIKHDEDC 1588

Query: 1014 LNALLKQKD-EEIIAL-NQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQL 1071
             + LL+ ++ ++++ + N+K +    ++ + +++   +         N  E     + Q 
Sbjct: 1589 KHILLQSEEIQQVVDISNEKDDPTHQTFSNNLNNIVIEQQNEQILNSNQIEAKSDQNHQQ 1648

Query: 1072 LDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXX 1131
            +DSK   +  QIL+   ++QIK ++E          K++ M   S IE  +++ N+ D  
Sbjct: 1649 IDSKFQADGEQILLSNSNNQIK-IQE----------KSDDM---SQIEVENENNNHED-- 1692

Query: 1132 XXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKII-QLETLNTELTGHDV 1190
                          ++E+ ++  + + EQ   LN   Q+ + +I+ Q +   ++    D 
Sbjct: 1693 --------------QQEDAMEIETQIDEQPDHLN---QDQFDQILDQNQQKESQYNNDDK 1735

Query: 1191 VNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADF 1250
            + Q+   + K    Q+   N ++L  + + + +I    D +     +L K+   ++E   
Sbjct: 1736 IKQQDSPKTKETEWQI-PNNLDILDYINQ-KQTIQKESDYQKISDVDL-KKEFDEKEYSA 1792

Query: 1251 QKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQ 1310
            +  +      L   E K  Q + + +   Q   ++I   +  T++ + + D E+ L+  Q
Sbjct: 1793 EFIKKSSPNSLEILEMK--QNISNDKKEEQSYKSEIKLGDANTNIGSVMLDMEKFLK--Q 1848

Query: 1311 EKYADVINQIEILRSEIEDEKV 1332
            +  +D+ NQ  +  SEI++E V
Sbjct: 1849 KGLSDLKNQSTVPNSEIKNENV 1870



 Score = 80.6 bits (190), Expect = 3e-13
 Identities = 214/1192 (17%), Positives = 499/1192 (41%), Gaps = 83/1192 (6%)

Query: 176  QEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDE 235
            QE++  + Q+++  N                         Q + +  +     ++E +  
Sbjct: 635  QEELKNESQLVQENNITKQIISNQFSQLQSNQVKSTSQISQYIQQEIQPLSLQKSEEQSS 694

Query: 236  KQRLLKDIESKDVRISSLEEANKLLEAARFEI--SLEHSKLAQELEQXXXXXXXXXXXXX 293
             Q+ L   +     IS  +E++K       ++  +L+  +  +E EQ             
Sbjct: 695  FQQNLTQTQQNQNEISLEKESSKQSAQKLSQLLDTLDRMEEEEENEQKIETETIQNQNNI 754

Query: 294  XLAKQSIEPSCEEKTEIEEKGSL-EIANMTELT-KKIELLEHLNCQIRQTNKELENKLAT 351
               K+      +E+ E E +G   ++ N+ +    + +LL        QTN  LE+K   
Sbjct: 755  LNEKEITNAQMDEEKEEEIRGQANQMDNLFQNNPNQDDLLIDQQISNNQTNISLESKNQV 814

Query: 352  MGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINK-NEIAKL 410
               ES+     S+      + +  ++    + S  S L  +   Q   K IN+  E  KL
Sbjct: 815  QIEESQMKPETSQSFKQEDTEQDNKSVEKLIASNKSSLQKD---QSLTKVINQIEECEKL 871

Query: 411  EMVIQSL---NKDLVDKEYVISEK-DTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLI 466
            + +I      N+   +++ +I+E  +             D+  + LQ + +      S I
Sbjct: 872  DKIIDENDEENQSKTNQQQIITESIEKNQNEKNSMEKFNDSNKSSLQKD-KSLSSILSQI 930

Query: 467  HVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEI---DAAN 523
                  ED +E  ++Q     +L D  K+ N+   I+  +  E ++++ N ++    +  
Sbjct: 931  EEFEKMEDEDEKEEIQVSKIDQL-DHFKNNNLLQNIQMDQEKEIEMSKNNQQLLEQQSTQ 989

Query: 524  KNMIKV--KSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGN- 580
             N + +  K++++ +  Q Q   +N     +  K+  + T   +  +Q++ E++E     
Sbjct: 990  NNQLDINEKTSNQNEYNQ-QIDQNNLQSQKEELKQQDQQTFIENQNNQQLNEVQESNSQQ 1048

Query: 581  -LQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDE 639
             +Q+ +   D+ ++I +   +  I+ ++  ++ +K   + ++ K    QE H +  +  +
Sbjct: 1049 EIQIEMNLKDNNQVINN--LQNDIQPKD-EQSEIKTCQIQDNDKEINQQEQHQINSQLLK 1105

Query: 640  VEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVI-ENLKLDKEQLYGTIKD 698
            + D  +  SQ    Q  +  ++ H  +QI  +    ++L  +  ENL  D +QL     D
Sbjct: 1106 IIDDSSSSSQSNDSQEVNFQQNEH--QQILNIQNENQQLDQIEQENLINDSDQLVEVSND 1163

Query: 699  -LENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKI 757
             ++N  E    ++QN I  N  L    E    ++ ++ +  I  + Q     Q  ++ +I
Sbjct: 1164 KVQNTFEQQNEQIQN-INHNQ-LNQFEEYAIQDQNNKQIENIETQNQQNSLVQENLE-QI 1220

Query: 758  QERDLYIENI-ESELSKYKSRICRLEESIAV----MEDRRYSLERKADQLGSYL--QEKQ 810
             E ++ I  I +  L K   +I   +E   +     ++    +  + D L   +  + +Q
Sbjct: 1221 TELNVNINQINQHNLLKQTEQIEENKEQNDIEQLDFQNDEQQIYTQVDILSKEVASENQQ 1280

Query: 811  KAYSEYTIQEDELVNRLAVLMDHDRVVEK-QLLEIEHENKELQKKNQILLEENQNLQISL 869
            ++  +  IQ +E   ++  L D    + K +++E+  ++   Q++  IL+++ Q  Q   
Sbjct: 1281 QSNEKQQIQVEEKEQQITELKDQLPEINKHEIIEVNQQSIHEQEQQSILMQKQQ--QYVE 1338

Query: 870  SDMQQHYNALVEKANRTDLAESEST-KYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDL 928
            +  QQ   + V +  + D  +  S  K Q Q+ D E  + +++ +   +  QK ++   +
Sbjct: 1339 AKEQQTTQSEVNRYLQVDAKQQISELKQQIQVED-EQIVDQVSSQ---ITEQKNQQQSQI 1394

Query: 929  EIEFNT-QIESAIR-DKKV-LNEKYEKNIEY-VTQLEAQLQEYKNNIENLNMNVEELNKM 984
            + +++  QI++ +  D+ + +++K ++N  Y V QLE ++++    I+      +++++ 
Sbjct: 1395 QEQYHVEQIQNIVENDQSISIDQKQQQNCVYEVQQLEQEIEQQGKEIDEQQQ--QQVSQQ 1452

Query: 985  NLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVS 1044
            +++L +  +Q+++       + +I E  +   +++Q  +    +N+     +V       
Sbjct: 1453 SIQL-NTQIQEEEKL---LQQSHIEEDLQQKLIVEQNQQIFQCVNEVQQQQKVIDDKQQE 1508

Query: 1045 DYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEM 1104
              E  L + + +    +EE    SKQ L  +Q ++++Q   ++Q  +  +  E  +    
Sbjct: 1509 SVEQSLHEQSAQQREQKEEFSEPSKQQLIDQQASQKIQGEEKQQKIEENDKSELVIDTSN 1568

Query: 1105 NIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKL 1164
             +   E   ++S I+   +D  ++              ++Q+  +   E+     Q+   
Sbjct: 1569 QLEIQEEKQVTSIIK-HDEDCKHI---------LLQSEEIQQVVDISNEKDDPTHQT--F 1616

Query: 1165 NTELQECYTKIIQLETLNT-ELTGHDVVNQEQI-NQLKSKLEQLNTENDNLLSTVAELRS 1222
            +  L     +    + LN+ ++      N +QI ++ ++  EQ+   N N    + E   
Sbjct: 1617 SNNLNNIVIEQQNEQILNSNQIEAKSDQNHQQIDSKFQADGEQILLSNSNNQIKIQEKSD 1676

Query: 1223 SISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAF-ESKYEQLLDSVQSSTQE 1281
             +S        E+      H  Q+E D  + E ++  Q     + +++Q+LD  Q    +
Sbjct: 1677 DMSQ------IEVENENNNHEDQQE-DAMEIETQIDEQPDHLNQDQFDQILDQNQQKESQ 1729

Query: 1282 ETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVA 1333
              N     +Q +    K ++ E  + N  +   D INQ + ++ E + +K++
Sbjct: 1730 YNNDDKIKQQDSP---KTKETEWQIPNNLD-ILDYINQKQTIQKESDYQKIS 1777



 Score = 56.0 bits (129), Expect = 8e-06
 Identities = 197/1083 (18%), Positives = 446/1083 (41%), Gaps = 137/1083 (12%)

Query: 160  VLQVKMKIMETTILDLQEKINEKDQIIEAKN-KATTXXXXXXXXXXXXXXXXXEDTKQQM 218
            +L ++ +  +   ++ +  IN+ DQ++E  N K                       ++  
Sbjct: 1132 ILNIQNENQQLDQIEQENLINDSDQLVEVSNDKVQNTFEQQNEQIQNINHNQLNQFEEYA 1191

Query: 219  TKMQENFIAMEAEWKDEKQRL----LKDIESKDVRISSLEEANKLLEAARFEISLEHSKL 274
             + Q N      E ++++  L    L+ I   +V I+ + + N L +  +    +E +K 
Sbjct: 1192 IQDQNNKQIENIETQNQQNSLVQENLEQITELNVNINQINQHNLLKQTEQ----IEENKE 1247

Query: 275  AQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHL 334
              ++EQ              +   S E + E + +  EK  +++       +K + +  L
Sbjct: 1248 QNDIEQ-LDFQNDEQQIYTQVDILSKEVASENQQQSNEKQQIQV------EEKEQQITEL 1300

Query: 335  NCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETL 394
              Q+ + NK   +++  +  +S       ++ S L+ ++     A + ++  S++ +  L
Sbjct: 1301 KDQLPEINK---HEIIEVNQQS---IHEQEQQSILMQKQQQYVEAKEQQTTQSEV-NRYL 1353

Query: 395  NQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQL 454
              D      K +I++L+  IQ  ++ +VD+   +S + T           +   + Q+  
Sbjct: 1354 QVDA-----KQQISELKQQIQVEDEQIVDQ---VSSQITEQKNQQQSQIQEQYHVEQI-- 1403

Query: 455  EHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQ 514
              Q  +E    I +    +  N + +VQ QL+QE+  + K+++ +   +  + + +  TQ
Sbjct: 1404 --QNIVENDQSISIDQKQQQ-NCVYEVQ-QLEQEIEQQGKEIDEQQQQQVSQQSIQLNTQ 1459

Query: 515  LNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEI-----VRLTEELHHLSQ 569
            + +E     ++ I+     KL ++Q Q+     ++V    K I       + + LH  S 
Sbjct: 1460 IQEEEKLLQQSHIEEDLQQKLIVEQNQQIFQCVNEVQQQQKVIDDKQQESVEQSLHEQSA 1519

Query: 570  KVAELEEEKGN-LQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQ 628
            +  E +EE     +  L+D  + + I+ +  ++ IE  + +E  +   + LE Q+   V 
Sbjct: 1520 QQREQKEEFSEPSKQQLIDQQASQKIQGEEKQQKIEENDKSELVIDTSNQLEIQEEKQVT 1579

Query: 629  EL--------HILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELAL 680
             +        HIL Q  +E++ ++ DIS  + D    +  S +L    + +   + E  L
Sbjct: 1580 SIIKHDEDCKHILLQS-EEIQ-QVVDISN-EKDDPTHQTFSNNLN---NIVIEQQNEQIL 1633

Query: 681  VIENLKLDKEQLYGTI-KDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKI 739
                ++   +Q +  I    + D E I+    N     + + +K + MS  ++       
Sbjct: 1634 NSNQIEAKSDQNHQQIDSKFQADGEQILLSNSN---NQIKIQEKSDDMSQIEVEN--ENN 1688

Query: 740  NHEEQS----KIQTQFG--IDAKIQER-DLYIENIESELSKYKSRICRLEESIAVMEDRR 792
            NHE+Q     +I+TQ     D   Q++ D  ++  + + S+Y +     ++     ++  
Sbjct: 1689 NHEDQQEDAMEIETQIDEQPDHLNQDQFDQILDQNQQKESQYNNDDKIKQQDSPKTKETE 1748

Query: 793  YSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQ 852
            + +    D L  Y+ +KQ      TIQ++          D+ ++ +  L + E + KE  
Sbjct: 1749 WQIPNNLDIL-DYINQKQ------TIQKES---------DYQKISDVDLKK-EFDEKEYS 1791

Query: 853  KKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITH 912
             +    ++++    + + +M+Q+ +         D  E +S K + +L D  +N+  +  
Sbjct: 1792 AE---FIKKSSPNSLEILEMKQNIS--------NDKKEEQSYKSEIKLGDANTNIGSVML 1840

Query: 913  EHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIE 972
            + +  +  K+K + DL      + +S + + ++ NE    N++ V    ++L +      
Sbjct: 1841 DMEKFL--KQKGLSDL------KNQSTVPNSEIKNE----NVDIVLSTNSKLTQ------ 1882

Query: 973  NLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKI 1032
                 V++ +K N     + +Q +  QS    EQ  NE   L +L K++  +I+ +N  +
Sbjct: 1883 -----VQQEDKQN-----QCLQLRSDQSLFQKEQDHNERKNL-SLEKKQIFDIVNINNNV 1931

Query: 1033 NNAQVSYMSMVSDYESKLAQFTTKLENME-EEMQRVSKQLLDSKQHNEELQILVREQDDQ 1091
             +    ++   S  +          E  E E+++   K            + + RE D  
Sbjct: 1932 LSQMDQFLIQKSSQKDNFLNGDNIQEKQEIEQIESADKNYSFGNNSENIFERIKRESD-- 1989

Query: 1092 IKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFI 1151
             K+L+E+   F+++  +   +I+++   P +  A +                  +   F+
Sbjct: 1990 -KKLQES--GFQISSDQRNSLIVTNIFTPSNAKAISDCGGAQTQFSNESFGITPKRINFL 2046

Query: 1152 QERSVLQEQSAKLNT--ELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTE 1209
            Q     + ++ ++NT  + Q+ Y   +++      +   + + Q   N   S   QLN+ 
Sbjct: 2047 QSNKKSEAEATQINTDSQFQQLYQSKLKIADDQKLVEPKEELTQNTSNSNIS--SQLNSS 2104

Query: 1210 NDN 1212
            N+N
Sbjct: 2105 NEN 2107


>UniRef50_A0CVZ5 Cluster: Chromosome undetermined scaffold_3, whole
            genome shotgun sequence; n=4; Paramecium tetraurelia|Rep:
            Chromosome undetermined scaffold_3, whole genome shotgun
            sequence - Paramecium tetraurelia
          Length = 933

 Score =  124 bits (299), Expect = 2e-26
 Identities = 144/676 (21%), Positives = 313/676 (46%), Gaps = 68/676 (10%)

Query: 468  VGTNTEDVNEIAKVQEQLK----------QELNDEI--KDVNVKDLIEKLKSAEEQITQL 515
            + T  ED N++  + EQL+          Q+LN  +  ++  V + I+K   AEE+  Q 
Sbjct: 263  ISTMAEDYNKLKTILEQLQTKMTALVQENQKLNKNLIEQEQKVTEEIKKKLLAEEKANQA 322

Query: 516  NDEIDAANKNM-IKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAEL 574
            N E +   + + I  K N +LK K + +  D+F  +S      V++ +E+++   K  +L
Sbjct: 323  NKEFNRVFECLQINQKENEELKNKLISQ--DSFKNLSIQTSNRVQM-DEINNYKMKNQQL 379

Query: 575  EEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQ 634
            + E   L++      + +  + ++ K    ++++  +  K    LE +   L  E   L+
Sbjct: 380  QNELEQLEMKYKQLLTEKNNQKEIPKSPSILKSIHSSSTKQSEQLELKLLQLQIENDNLK 439

Query: 635  QK--YDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQL 692
             +  +++V+ K+ D       ++  +IKS+  E+ I     S+++   +  NL++  EQL
Sbjct: 440  AEMAHNQVDSKVIDSKNDMIQKLEDKIKSILKEKSI-----SEEQSIQICHNLEIMNEQL 494

Query: 693  YGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFG 752
               +++ E++   ++ +     +++ +  + L +M   K +E   ++  ++  K+  +F 
Sbjct: 495  KNGLQNKESEVSSLLKQKNESERDHRNQINYLNQML--KGTEDKVQVAKQDYQKLLDEFK 552

Query: 753  -IDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQK 811
             ID +  +    + N E +L +    +   +  +    DR +  + + DQ+   LQ++ +
Sbjct: 553  QIDLRKSKLQEDLRNSEKKLDQLNQELAFTKGELKKSSDRNHQFQAQHDQMNQQLQQQSQ 612

Query: 812  AYSEYTIQEDELV-NRLAVLMDHDRVVEKQLLEIEHENK-ELQKKNQILLEENQNLQISL 869
               +   Q D L  +   + M+++++ EKQ+  ++ E K ++ + N+++  + +  Q   
Sbjct: 613  LQQQLLQQIDGLKQSEQQIRMEYEKL-EKQMQAVKSEMKYQVTELNEMISLQARKTQ--- 668

Query: 870  SDMQQHYNALVEK-ANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDL 928
             + ++  N L+E+     D  E +    Q  + DLE  LK    + + L+  K++EI DL
Sbjct: 669  -EKERQLNELIEEMGGMRDQYEVQKKVCQENVNDLERRLKNQRLQQEELLQVKEQEILDL 727

Query: 929  EIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLEL 988
            +   + QI+   +   + +  Y++  +   QL+A+L    + IE L   VE++   N  +
Sbjct: 728  KQTMDQQIKMLDKRNALSSFDYDQREQ---QLQAELLSKNDQIEGLKSEVEKVRSNNFNI 784

Query: 989  IDKHVQK--QQTQSPDYTEQYINEINK-------LNALLKQKDEEIIALNQKINN----- 1034
             ++ +++  Q  Q       Y NE+ +       L+ +LK++ EE   L+Q +       
Sbjct: 785  QEELLRQGMQLNQHQATIANYKNELTQSRQEQQHLSEMLKKRKEETEQLHQNLEEMRREL 844

Query: 1035 -----AQVSYMSMVSDYESKLA---------QFTTKLENMEEEMQRVSKQLLDSKQHNEE 1080
                 +  S  S++   + ++A             K+  +  EM R S++L    + NEE
Sbjct: 845  QSKKMSDDSRRSVLRQQDLQIALENLSRENLSLQQKINGLSNEMNRKSREL---SERNEE 901

Query: 1081 LQILVREQDDQIKELK 1096
             QIL R+ D+ +  L+
Sbjct: 902  YQILKRKYDETVANLE 917



 Score = 79.4 bits (187), Expect = 8e-13
 Identities = 147/739 (19%), Positives = 322/739 (43%), Gaps = 62/739 (8%)

Query: 617  SLLESQKFDLVQELHILQQKYDEVEDKLADI-SQLQSDQVCSEIKSVHLEEQIDALSASK 675
            S L SQ  +L+Q    +Q +   +   L D+ S +Q      ++     ++ I+ L+  +
Sbjct: 184  SRLSSQNINLMQSKPKIQTEIYRISGALRDLMSSIQKMMGDGKLPDQINDKMIEILANFR 243

Query: 676  K--ELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQN----YIQENMDLTDKLEKMSA 729
            K  E+A        D +    T+ +  N  + I+ +LQ      +QEN  L   L +   
Sbjct: 244  KLEEIANSEPMPASDNDSKISTMAEDYNKLKTILEQLQTKMTALVQENQKLNKNLIEQEQ 303

Query: 730  EKISELLAKINHEEQ-SKIQTQFG-IDAKIQERDLYIENIESEL-SKYKSRICRLEESIA 786
            +   E+  K+  EE+ ++   +F  +   +Q      E ++++L S+   +   ++ S  
Sbjct: 304  KVTEEIKKKLLAEEKANQANKEFNRVFECLQINQKENEELKNKLISQDSFKNLSIQTSNR 363

Query: 787  VMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQED---ELVNRLAVLMDHDRVVEKQLLE 843
            V  D   + + K  QL + L++ +  Y +   +++   E+    ++L        KQ  +
Sbjct: 364  VQMDEINNYKMKNQQLQNELEQLEMKYKQLLTEKNNQKEIPKSPSILKSIHSSSTKQSEQ 423

Query: 844  IEHENKELQKKNQILLEENQNLQI------SLSDMQQHYNALVEK-ANRTDLAESESTKY 896
            +E +  +LQ +N  L  E  + Q+      S +DM Q     ++       ++E +S + 
Sbjct: 424  LELKLLQLQIENDNLKAEMAHNQVDSKVIDSKNDMIQKLEDKIKSILKEKSISEEQSIQI 483

Query: 897  QTQL----RDLESNLKRITHEHQTLIVQKKKEIED--LEIEFNTQIESAIRDK-KVLNEK 949
               L      L++ L+    E  +L+ QK +   D   +I +  Q+     DK +V  + 
Sbjct: 484  CHNLEIMNEQLKNGLQNKESEVSSLLKQKNESERDHRNQINYLNQMLKGTEDKVQVAKQD 543

Query: 950  YEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYIN 1009
            Y+K ++   Q++ +  + + ++ N   + ++L+++N EL     + +  +S D   Q+  
Sbjct: 544  YQKLLDEFKQIDLRKSKLQEDLRN---SEKKLDQLNQEL--AFTKGELKKSSDRNHQFQA 598

Query: 1010 EINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSK 1069
            + +++N  L+Q+ +    L Q+I+  + S   +  +Y           E +E++MQ V  
Sbjct: 599  QHDQMNQQLQQQSQLQQQLLQQIDGLKQSEQQIRMEY-----------EKLEKQMQAVKS 647

Query: 1070 QL-LDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNV 1128
            ++     + NE + +  R+  ++ ++L E  L  EM   + +  +     +   ++ N++
Sbjct: 648  EMKYQVTELNEMISLQARKTQEKERQLNE--LIEEMGGMRDQYEVQKKVCQ---ENVNDL 702

Query: 1129 DXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGH 1188
            +            L   +E+E +  +  + +Q   L+   +         +    +L   
Sbjct: 703  ERRLKNQRLQQEELLQVKEQEILDLKQTMDQQIKMLD---KRNALSSFDYDQREQQLQAE 759

Query: 1189 DVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREA 1248
             +   +QI  LKS++E++ + N N+   +  LR  +   ++Q    IA  +K  L Q   
Sbjct: 760  LLSKNDQIEGLKSEVEKVRSNNFNIQEEL--LRQGMQ--LNQHQATIAN-YKNELTQSR- 813

Query: 1249 DFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRN 1308
              Q+ +H L   L   + + EQL  +++   +E  +K ++ +   S+  + QD +  L N
Sbjct: 814  --QEQQH-LSEMLKKRKEETEQLHQNLEEMRRELQSKKMSDDSRRSVLRQ-QDLQIALEN 869

Query: 1309 LQEKYADVINQIEILRSEI 1327
            L  +   +  +I  L +E+
Sbjct: 870  LSRENLSLQQKINGLSNEM 888



 Score = 78.6 bits (185), Expect = 1e-12
 Identities = 139/690 (20%), Positives = 295/690 (42%), Gaps = 70/690 (10%)

Query: 212 EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271
           E  + +MT + +    +     +++Q++ ++I+ K +      +ANK      FE    +
Sbjct: 278 EQLQTKMTALVQENQKLNKNLIEQEQKVTEEIKKKLLAEEKANQANKEFNRV-FECLQIN 336

Query: 272 SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELL 331
            K  +EL+                   SI+ S   + +++E  + ++ N  +L  ++E L
Sbjct: 337 QKENEELKNKLISQDS-------FKNLSIQTS--NRVQMDEINNYKMKNQ-QLQNELEQL 386

Query: 332 EHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSS 391
           E    Q+  T K  + ++    +  K++ S S K S  +  K       +++     L +
Sbjct: 387 EMKYKQLL-TEKNNQKEIPKSPSILKSIHSSSTKQSEQLELK-----LLQLQIENDNLKA 440

Query: 392 ETLNQDTDKKI--NKNE-IAKLEMVIQSLNKDL-VDKEYVISEKDTXXXXXXXXXXG--- 444
           E  +   D K+  +KN+ I KLE  I+S+ K+  + +E  I               G   
Sbjct: 441 EMAHNQVDSKVIDSKNDMIQKLEDKIKSILKEKSISEEQSIQICHNLEIMNEQLKNGLQN 500

Query: 445 KDTLIAQL--QLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKD-- 500
           K++ ++ L  Q    +      + ++    +   +  +V +Q  Q+L DE K ++++   
Sbjct: 501 KESEVSSLLKQKNESERDHRNQINYLNQMLKGTEDKVQVAKQDYQKLLDEFKQIDLRKSK 560

Query: 501 LIEKLKSAEEQITQLNDEIDAANKNMIKVKS--NHKLKLKQMQKTIDNFSKVSDSNKEIV 558
           L E L+++E+++ QLN E+ A  K  +K  S  NH+ + +  Q       + S   ++++
Sbjct: 561 LQEDLRNSEKKLDQLNQEL-AFTKGELKKSSDRNHQFQAQHDQMN-QQLQQQSQLQQQLL 618

Query: 559 RLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISL 618
           +  + L    Q++  +E EK   Q+  V        +S++  ++ E+  +   + +    
Sbjct: 619 QQIDGLKQSEQQI-RMEYEKLEKQMQAV--------KSEMKYQVTELNEMISLQARKTQE 669

Query: 619 LESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKEL 678
            E Q  +L++E+  ++ +Y EV+ K           VC E  +  LE ++      ++EL
Sbjct: 670 KERQLNELIEEMGGMRDQY-EVQKK-----------VCQENVN-DLERRLKNQRLQQEEL 716

Query: 679 ALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKIS--ELL 736
             V E   LD +Q      D +    D  N L ++     D   + +++ AE +S  + +
Sbjct: 717 LQVKEQEILDLKQTM----DQQIKMLDKRNALSSF-----DYDQREQQLQAELLSKNDQI 767

Query: 737 AKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLE 796
             +  E +      F I  ++  + + +   ++ ++ YK+ + +  +    + +     +
Sbjct: 768 EGLKSEVEKVRSNNFNIQEELLRQGMQLNQHQATIANYKNELTQSRQEQQHLSEMLKKRK 827

Query: 797 RKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQ 856
            + +QL   L+E ++      + +D   +R +VL   D  ++  L  +  EN  LQ+K  
Sbjct: 828 EETEQLHQNLEEMRRELQSKKMSDD---SRRSVLRQQD--LQIALENLSRENLSLQQKIN 882

Query: 857 ILLEENQNLQISLSDMQQHYNALVEKANRT 886
            L  E       LS+  + Y  L  K + T
Sbjct: 883 GLSNEMNRKSRELSERNEEYQILKRKYDET 912



 Score = 72.1 bits (169), Expect = 1e-10
 Identities = 110/587 (18%), Positives = 226/587 (38%), Gaps = 34/587 (5%)

Query: 1010 EINKLNALLKQKDEEIIAL---NQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQR 1066
            + NKL  +L+Q   ++ AL   NQK+N   +     V++   K      K     +E  R
Sbjct: 269  DYNKLKTILEQLQTKMTALVQENQKLNKNLIEQEQKVTEEIKKKLLAEEKANQANKEFNR 328

Query: 1067 VSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDAN 1126
            V + L  +++ NEEL+  +  QD      K   +     +   E        + + ++  
Sbjct: 329  VFECLQINQKENEELKNKLISQDS----FKNLSIQTSNRVQMDEINNYKMKNQQLQNELE 384

Query: 1127 NVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELT 1186
             ++             +   ++E  +  S+L+   +    + ++   K++QL+  N  L 
Sbjct: 385  QLEMKYKQLLT-----EKNNQKEIPKSPSILKSIHSSSTKQSEQLELKLLQLQIENDNLK 439

Query: 1187 GHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVD-QRGFEIA-ELWKQHLA 1244
                 NQ     + SK + +    D + S + E   S   ++      EI  E  K  L 
Sbjct: 440  AEMAHNQVDSKVIDSKNDMIQKLEDKIKSILKEKSISEEQSIQICHNLEIMNEQLKNGLQ 499

Query: 1245 QREADF-----QKTEHEL--RVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQN 1297
             +E++      QK E E   R Q++      +   D VQ + Q+    +   +Q+   ++
Sbjct: 500  NKESEVSSLLKQKNESERDHRNQINYLNQMLKGTEDKVQVAKQDYQKLLDEFKQIDLRKS 559

Query: 1298 KLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQ 1357
            KLQ   E LRN ++K   +  ++   + E++                        + + Q
Sbjct: 560  KLQ---EDLRNSEKKLDQLNQELAFTKGELKKSSDRNHQFQAQHDQMNQQLQQQSQLQQQ 616

Query: 1358 SYKQMQ--EQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSE 1415
              +Q+   +QS   I  E  +L+K               +N+  +     T + E + +E
Sbjct: 617  LLQQIDGLKQSEQQIRMEYEKLEKQMQAVKSEMKYQVTELNEMISLQARKTQEKERQLNE 676

Query: 1416 IYQK----THEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENAN 1471
            + ++      +Y +      +   ++ ++L     + E+L   KE E+  L+  M +   
Sbjct: 677  LIEEMGGMRDQYEVQKKVCQENVNDLERRLKNQRLQQEELLQVKEQEILDLKQTMDQQIK 736

Query: 1472 HYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEI 1531
              +     S  +  +  ++L     E +S N Q+  L   +E+  +    +Q  L  Q +
Sbjct: 737  MLDKRNALSSFDYDQREQQLQ---AELLSKNDQIEGLKSEVEKVRSNNFNIQEELLRQGM 793

Query: 1532 EIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNK 1578
            ++      I N +N +  S  + Q+H+S     ++   EQL   + +
Sbjct: 794  QLNQHQATIANYKNELTQSRQE-QQHLSEMLKKRKEETEQLHQNLEE 839



 Score = 68.5 bits (160), Expect = 1e-09
 Identities = 131/689 (19%), Positives = 277/689 (40%), Gaps = 60/689 (8%)

Query: 849  KELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLK 908
            ++LQ K   L++ENQ L  +L + +Q    + E+  +  LAE ++ +   +   +   L+
Sbjct: 278  EQLQTKMTALVQENQKLNKNLIEQEQ---KVTEEIKKKLLAEEKANQANKEFNRVFECLQ 334

Query: 909  RITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYK 968
                E++ L  + K   +D     + Q  + ++  ++ N K  KN           Q+ +
Sbjct: 335  INQKENEEL--KNKLISQDSFKNLSIQTSNRVQMDEINNYKM-KN-----------QQLQ 380

Query: 969  NNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIAL 1028
            N +E L M  ++L      L +K+ QK+  +SP   +   +   K +  L     E+  L
Sbjct: 381  NELEQLEMKYKQL------LTEKNNQKEIPKSPSILKSIHSSSTKQSEQL-----ELKLL 429

Query: 1029 NQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQ 1088
              +I N  +      +  +SK+        +M ++++   K +L  K  +EE  I +   
Sbjct: 430  QLQIENDNLKAEMAHNQVDSKVID---SKNDMIQKLEDKIKSILKEKSISEEQSIQICHN 486

Query: 1089 DDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKV--QE 1146
             + + E  +  L    N       ++    E   D  N ++            ++V  Q+
Sbjct: 487  LEIMNEQLKNGL---QNKESEVSSLLKQKNESERDHRNQINYLNQMLKGTEDKVQVAKQD 543

Query: 1147 EEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQL 1206
             ++ + E   +  + +KL  +L+    K+ QL        G    + ++ +Q +++ +Q+
Sbjct: 544  YQKLLDEFKQIDLRKSKLQEDLRNSEKKLDQLNQELAFTKGELKKSSDRNHQFQAQHDQM 603

Query: 1207 N---TENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLA-QREADFQKTEHELRVQLS 1262
            N    +   L   + +    +  +  Q   E  +L KQ  A + E  +Q TE    + L 
Sbjct: 604  NQQLQQQSQLQQQLLQQIDGLKQSEQQIRMEYEKLEKQMQAVKSEMKYQVTELNEMISLQ 663

Query: 1263 A--FESKYEQLLDSVQS----STQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADV 1316
            A   + K  QL + ++       Q E  K V  E V  L+ +L+++    R  QE+   V
Sbjct: 664  ARKTQEKERQLNELIEEMGGMRDQYEVQKKVCQENVNDLERRLKNQ----RLQQEELLQV 719

Query: 1317 INQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTEN-QSYKQMQEQSILNINEENA 1375
              Q  +   +  D+++                  D R +  Q+    +   I  +  E  
Sbjct: 720  KEQEILDLKQTMDQQIKM----LDKRNALSSFDYDQREQQLQAELLSKNDQIEGLKSEVE 775

Query: 1376 QLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFE 1435
            +++ ++            ++N  +A +    ++L    ++  Q+    +  L +R +E E
Sbjct: 776  KVRSNNFNIQEELLRQGMQLNQHQATIANYKNEL----TQSRQEQQHLSEMLKKRKEETE 831

Query: 1436 NVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVK-LIEELNVK 1494
             + Q L E  + ++      +S  ++LR +  + A    + +  S  +++  L  E+N K
Sbjct: 832  QLHQNLEEMRRELQSKKMSDDSRRSVLRQQDLQIALENLSRENLSLQQKINGLSNEMNRK 891

Query: 1495 ITESVSLNKQVAELNKALEEEVAKTNEMQ 1523
              E    N++   L +  +E VA    ++
Sbjct: 892  SRELSERNEEYQILKRKYDETVANLERLE 920


>UniRef50_P75471 Cluster: Cytadherence high molecular weight protein
            2; n=6; Mycoplasma|Rep: Cytadherence high molecular
            weight protein 2 - Mycoplasma pneumoniae
          Length = 1818

 Score =  124 bits (299), Expect = 2e-26
 Identities = 230/1148 (20%), Positives = 490/1148 (42%), Gaps = 106/1148 (9%)

Query: 498  VKDLIEKLKSAEEQITQLNDE----IDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDS 553
            V +L  K +  ++++ +L  E    +++   N    +SN++LKL Q Q  ID  ++    
Sbjct: 106  VAELNNKARFFKDELKRLQQENAAFVNSRYANWADFQSNYQLKLDQFQALIDQQNQTIKQ 165

Query: 554  NKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRL 613
              E +   + L  + Q V  L++   N  L   + D+       +Y ++ E+EN  + RL
Sbjct: 166  LNEQIAANQGL--IDQNVQRLQQ---NHSLDQQERDALLYEVDHLYNELYELEN--QKRL 218

Query: 614  KAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSA 673
              I   E+   DLV     LQ  Y+ +    A+  Q Q D   +++K V  E+QI     
Sbjct: 219  VGIE-YEATYQDLVSADAELQNVYETIAQNQANF-QKQCDAYWAQLKQV--EQQI---QT 271

Query: 674  SKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKL--QNYI--QENMDLTDKLEKMSA 729
            +K+EL      LK+        I     + +D+ +K+  ++++  ++  D+   L  ++ 
Sbjct: 272  TKQELVDEESTLKVRLNDADFYINSRLAELDDLTSKINERDFVSKEQAQDVKASLANLTK 331

Query: 730  EKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVME 789
            EK   L A+ +  E+ +      I+   QE  L+ +++E +  +++    + +ES+  +E
Sbjct: 332  EK-ERLSAEKDSFERLRNTALNDINRMEQENALFAKHLEQQQYEFER---KQQESLLKLE 387

Query: 790  DRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHE-- 847
                 L+++   +G +  E +       IQE EL+ +   +   D ++ +  LE E +  
Sbjct: 388  TEHKQLQKR---IGEFKIESEAKSEALLIQERELLEKRREI---DDLLTQASLEYEQQRR 441

Query: 848  -NKELQKKNQILLEENQNLQISLS--DMQQHYNALVEKANRTDLAESESTKYQTQLRDLE 904
             N+ L++K++ + +  QNL  +    D ++HY A  ++ +   + + +  K  T+ R+LE
Sbjct: 442  TNQVLKEKHRQVQQHFQNLVHAKKKLDQKRHYLAEQKRIDEEQIFKLKE-KIATERRELE 500

Query: 905  -----SNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQ 959
                    K+   E+  LI +  K++   + +F  +IE    +     +  +K+   +  
Sbjct: 501  KLYLVKKQKQDQKENDLLIFE--KQLRQYQADFENEIEEKQNELFASQKSLQKSFTQLKN 558

Query: 960  LEAQLQEYKNNIEN--LNMNVEELNKMNLELI----DKHVQKQQTQSPDYTEQYINEINK 1013
             EA+L +    I     ++   + +  +LE+       H+Q+++ +  +   Q+ N ++ 
Sbjct: 559  KEAELNQKAQKIAEDWAHLKQNKHHHADLEIFLEGEFNHLQQEKHKLLEARTQFDNRVSL 618

Query: 1014 LNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLD 1073
            L+A  KQK  E++   Q +     ++     + E+    +  +L N+E++     K++L 
Sbjct: 619  LSARFKQKQAELVKQKQSLEQLTAAFN---KEQEAVERDWKDRLANLEKQ-----KEMLG 670

Query: 1074 SKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXX 1133
             K H  +   L     +  K+L E +L  +    + E      +++  ++    +     
Sbjct: 671  DKVHQFDENSL-----NISKKLAERELAIKFKEKELEAAQKQLSLDNNNNAGLKLQLDKL 725

Query: 1134 XXXXXXXXLKVQEEEEFIQE-RSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHD--- 1189
                    L+++  +E I +       + A   ++LQ    ++  LE    E        
Sbjct: 726  SESLKTERLELEASKERILDFYDESSRRIADYESDLQARLAEVKTLEKNQQETAAKSERE 785

Query: 1190 -VVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREA 1248
              V  E++NQ K    Q+  +    L  +A ++  ++   +    + AEL KQ   + EA
Sbjct: 786  LKVALEKLNQAKKAFLQIRKQQ---LLEIASVKQQLAQKANLLKNQQAELDKQ-TEELEA 841

Query: 1249 DF--QKTE-HELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEH 1305
             F  Q T+  EL   L + +SK ++LL+  +S   ++  +    E V   + ++  K   
Sbjct: 842  AFLEQDTDKKELEKALHSVKSK-QELLERERSFLLQKQREFA--EHVAGFKRQVHFKTTQ 898

Query: 1306 LRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQ 1365
            ++ L E   +   Q E ++ E E  K+AF                + +   Q +K+++  
Sbjct: 899  MQRLSE--FNKQQQSEQIKRETE-LKIAFADLKKDYQLFELQKNQEFQQIEQKHKELE-- 953

Query: 1366 SILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTI 1425
                + ++ A+LK+                  A+  +    H+LEL+ +   Q     ++
Sbjct: 954  ---LLAQKQAELKQELEQKATALASQDQDTVQAKLDLARQQHELELRQNAFNQA----SL 1006

Query: 1426 TLTQRNDEFEN-VRQQLVEYEKRIEDLTY------EKESELAILRLKMHENANHYETMQK 1478
            +L ++ ++  N V+    E +KR E LT       EKE +      ++++    +E    
Sbjct: 1007 SLNKQREQLTNQVKVLHGELKKRHEKLTLKDRLLAEKEKDQHKKDAEINQRFKQFENEYA 1066

Query: 1479 ESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVT-LN 1537
            + +  + + ++ELN         N  + +    L  + A   ++Q   +   +++ T + 
Sbjct: 1067 DFDQAKKRELQELNQIRRNLEQSNASLLKKRNQLTLDFALLRKVQHNTQTNRVQLNTQIK 1126

Query: 1538 DEITNLQNMVRAS-SSKIQKHV------SFASDTKQGRDEQLDNTMNKELLDAVPRAELD 1590
            + +   +N  +AS  + +QK +      SFAS  +  R+      +  +  D   ++E++
Sbjct: 1127 EFLLEKKNFQKASDEAALQKALLIKRLRSFASKLQLQREALAIQKLEFDKRDEQQKSEIN 1186

Query: 1591 LAMYMLHQ 1598
             A   L Q
Sbjct: 1187 NAKLQLEQ 1194



 Score =  110 bits (265), Expect = 3e-22
 Identities = 269/1546 (17%), Positives = 621/1546 (40%), Gaps = 142/1546 (9%)

Query: 90   ISESLANTLKQKEILMEKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXX---XQLGDVTH 146
            I+++ AN  KQ +    ++KQ ++  + +   +V                   +L ++  
Sbjct: 244  IAQNQANFQKQCDAYWAQLKQVEQQIQTTKQELVDEESTLKVRLNDADFYINSRLAELDD 303

Query: 147  LSNTIKEKDNALSVLQVKMKIMETTILDLQEKIN-EKDQIIEAKNKATTXXXXXXXXXXX 205
            L++ I E+D         +K     +   +E+++ EKD     +N A             
Sbjct: 304  LTSKINERDFVSKEQAQDVKASLANLTKEKERLSAEKDSFERLRNTALNDINRMEQENAL 363

Query: 206  XXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLK-DIESKDVRISSLEEANKLLEAAR 264
                  +   +   K QE+ + +E E K  ++R+ +  IES+    + L +  +LLE  R
Sbjct: 364  FAKHLEQQQYEFERKQQESLLKLETEHKQLQKRIGEFKIESEAKSEALLIQERELLEKRR 423

Query: 265  -FEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSI---EPSCEEKTE-IEEKGSLEIA 319
              +  L  + L  E ++                 Q++   +   ++K   + E+  ++  
Sbjct: 424  EIDDLLTQASLEYEQQRRTNQVLKEKHRQVQQHFQNLVHAKKKLDQKRHYLAEQKRIDEE 483

Query: 320  NMTELTKKIEL----LEHLNCQIRQTNKELENKLATMGTESKAVSSP------SKKGSPL 369
             + +L +KI      LE L    +Q   + EN L     + +   +        K+    
Sbjct: 484  QIFKLKEKIATERRELEKLYLVKKQKQDQKENDLLIFEKQLRQYQADFENEIEEKQNELF 543

Query: 370  ISRKSGRNTASKMKSPWSQLS--SETLNQD-TDKKINKNEIAKLEMVIQSLNKDLVDKEY 426
             S+KS + + +++K+  ++L+  ++ + +D    K NK+  A LE+ ++     L  +++
Sbjct: 544  ASQKSLQKSFTQLKNKEAELNQKAQKIAEDWAHLKQNKHHHADLEIFLEGEFNHLQQEKH 603

Query: 427  VISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDV-------NEIA 479
             + E  T           +     Q Q E  +  +    +    N E         + +A
Sbjct: 604  KLLEARTQFDNRVSLLSAR---FKQKQAELVKQKQSLEQLTAAFNKEQEAVERDWKDRLA 660

Query: 480  KVQEQLKQELNDEIK--DVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNH---K 534
             +++Q K+ L D++   D N  ++ +KL   E  I     E++AA K +    +N+   K
Sbjct: 661  NLEKQ-KEMLGDKVHQFDENSLNISKKLAERELAIKFKEKELEAAQKQLSLDNNNNAGLK 719

Query: 535  LKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMI 594
            L+L ++ +++       +++KE  R+ +     S+++A+ E +   LQ  L +  +    
Sbjct: 720  LQLDKLSESLKTERLELEASKE--RILDFYDESSRRIADYESD---LQARLAEVKTLEKN 774

Query: 595  ESDVYKKM-----IEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQ 649
            + +   K      + +E L + +   + + + Q  ++      L QK + ++++ A++  
Sbjct: 775  QQETAAKSERELKVALEKLNQAKKAFLQIRKQQLLEIASVKQQLAQKANLLKNQQAEL-- 832

Query: 650  LQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNK 709
               D+   E+++  LE+  D     KKEL   + ++K  K++L      LE ++  ++ K
Sbjct: 833  ---DKQTEELEAAFLEQDTD-----KKELEKALHSVK-SKQEL------LERERSFLLQK 877

Query: 710  LQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIES 769
             + + +       ++   + +   + L++ N ++QS+ Q +   + KI   DL  +    
Sbjct: 878  QREFAEHVAGFKRQVHFKTTQM--QRLSEFNKQQQSE-QIKRETELKIAFADLKKDYQLF 934

Query: 770  ELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAV 829
            EL K         +    +E +   LE  A +     QE ++  +    Q+ + V     
Sbjct: 935  ELQK--------NQEFQQIEQKHKELELLAQKQAELKQELEQKATALASQDQDTVQAKLD 986

Query: 830  LMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLA 889
            L      +E +       +  L K+ + L  +   +++   ++++ +  L  K     LA
Sbjct: 987  LARQQHELELRQNAFNQASLSLNKQREQLTNQ---VKVLHGELKKRHEKLTLKDRL--LA 1041

Query: 890  ESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEK 949
            E E  +++    ++    K+  +E+      KK+E+++L  +    +E +  +  +L ++
Sbjct: 1042 EKEKDQHKKDA-EINQRFKQFENEYADFDQAKKRELQELN-QIRRNLEQS--NASLLKKR 1097

Query: 950  YEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYIN 1009
             +  +++    + Q     N ++ LN  ++E       L  K+ QK   ++       I 
Sbjct: 1098 NQLTLDFALLRKVQHNTQTNRVQ-LNTQIKEFL-----LEKKNFQKASDEAALQKALLIK 1151

Query: 1010 EINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSK 1069
             +    + L+ + E +     + +       S +++ + +L QF  + +N +E  Q   K
Sbjct: 1152 RLRSFASKLQLQREALAIQKLEFDKRDEQQKSEINNAKLQLEQFKLEKQNFDEAKQ---K 1208

Query: 1070 QLLDSKQHNEELQI---LVREQDDQIKELKETKLTFEMNIPKTEGMIIS--STIEPMSDD 1124
            QL++ K   + L +   L++++  Q+K L ++ LT++     ++  +    + +  + + 
Sbjct: 1209 QLIEFKDQCQRLDVEKRLLKQKLVQLKNLSKSYLTYKNRADLSQQQLQHKYANLLELKEK 1268

Query: 1125 ANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTE 1184
                                Q   E  QE+  L     +++ + +        L+ L++E
Sbjct: 1269 LQTAKRALDKKHRAIYGKMAQFVSELRQEKKQLLSAQKQVDDKSRLLEQNQRHLQNLSSE 1328

Query: 1185 LTGHDVVNQEQINQL----KSKLEQLNTENDNLLSTVAELR---SSISSAVDQRGFEIAE 1237
                    +  IN+     K  +  +   +  L     EL+     +S    Q   E ++
Sbjct: 1329 TKKKRQSLEHDINKFDQRRKEAVSSILNSHKKLKQKEGELQGILQKLSLKKTQIEQEFSK 1388

Query: 1238 LWKQH--LAQREADFQKTEHELRVQLSAFESKYEQLLD-------SVQSSTQE----ETN 1284
            L++Q   L ++     K   EL+ Q  A   K  ++L+        +Q  T E    + N
Sbjct: 1389 LYQQREKLDRQRTTLSKLHRELKAQNEATAHKNREVLEIENYYKKELQRLTTEKSEFDNN 1448

Query: 1285 KIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXX 1344
            K    E    ++N+++ KE H++ + E+     + +E    ++  +K +           
Sbjct: 1449 KNRLFEYFRKIRNEIEKKEAHIKTVLEETQKKRHLVETEAVKLHLQKQSIISKGQELKEI 1508

Query: 1345 XXXXXXDLRTENQSYKQ----MQEQSIL--NINEENAQLKKSSXXXXXXXXXXXXRVNDA 1398
                  D+   N+  ++    + +  +L  N+ E   ++                ++++ 
Sbjct: 1509 KERVSRDISHTNKQREELNSLLHQNKLLQKNLAEREREINNKDSLLTQKIQTAKQKLSEK 1568

Query: 1399 EAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVE--YEKRIEDLTYEKE 1456
            EA++L+L  ++   + + YQ   E T   T+  D  +N  + L    ++    D+ Y   
Sbjct: 1569 EARILKLLEKMRAVEQQ-YQA--EITRLKTRNADLEKNDNKHLFPPLFKINGNDMNYPYP 1625

Query: 1457 SELAILRLKMHENANHYETM-QKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEE 1515
                  + K  +++N    + +++ +  + +   EL     +   L K++ ++   LE +
Sbjct: 1626 YPWFYPQQKQEDSSNQIRHLFEQQLQFMQQRYENELTELRRQRALLEKKLDQIQ--LESQ 1683

Query: 1516 V-AKTNE-------MQTALENQEIEIVTLNDEITNLQNMVRASSSK 1553
            + AK N+       MQ  LE  E ++   + +I  L   +    ++
Sbjct: 1684 LSAKKNDFEKVEQMMQKLLEKTEQKLSAFDQKINALAEQINTQKAE 1729



 Score =  103 bits (248), Expect = 3e-20
 Identities = 207/1124 (18%), Positives = 465/1124 (41%), Gaps = 72/1124 (6%)

Query: 498  VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEI 557
            V  L  +L   E Q   +  E +A  ++++   +  +   + + +   NF K  D+    
Sbjct: 202  VDHLYNELYELENQKRLVGIEYEATYQDLVSADAELQNVYETIAQNQANFQKQCDAYWAQ 261

Query: 558  VRLTEELHHLSQKVAELEEEKGNLQLHLVDYD---SGRMIE-SDVYKKMIEMENLAETRL 613
            ++  E+    +++  EL +E+  L++ L D D   + R+ E  D+  K+ E + +++ + 
Sbjct: 262  LKQVEQQIQTTKQ--ELVDEESTLKVRLNDADFYINSRLAELDDLTSKINERDFVSKEQA 319

Query: 614  KAISLLESQKFDLVQELHILQQKYDEVEDK-LADISQLQSDQVCSEIKSVHLEEQIDALS 672
            + +    +      + L   +  ++ + +  L DI++++ +     + + HLE+Q     
Sbjct: 320  QDVKASLANLTKEKERLSAEKDSFERLRNTALNDINRMEQENA---LFAKHLEQQQYEFE 376

Query: 673  ASKKELALVIENLKLDKEQLYGTIK-DLENDKEDIMNKLQNYIQENMDLTDKLEKMSAE- 730
              ++E  L +E      ++  G  K + E   E ++ + +  +++  ++ D L + S E 
Sbjct: 377  RKQQESLLKLETEHKQLQKRIGEFKIESEAKSEALLIQERELLEKRREIDDLLTQASLEY 436

Query: 731  ----KISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIA 786
                + +++L + + + Q   Q       K+ ++  Y+   +  + +   +I +L+E IA
Sbjct: 437  EQQRRTNQVLKEKHRQVQQHFQNLVHAKKKLDQKRHYLAE-QKRIDE--EQIFKLKEKIA 493

Query: 787  VME---DRRYSLER-KADQLGSYLQEKQKAYSEYTIQ-EDELVNRLAVLMDHDRVVEKQL 841
                  ++ Y +++ K DQ  + L   +K   +Y    E+E+  +   L    + ++K  
Sbjct: 494  TERRELEKLYLVKKQKQDQKENDLLIFEKQLRQYQADFENEIEEKQNELFASQKSLQKSF 553

Query: 842  LEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLR 901
             +++++  EL +K Q + E+  +L+ +          L  + N     + +  + +TQ  
Sbjct: 554  TQLKNKEAELNQKAQKIAEDWAHLKQNKHHHADLEIFLEGEFNHLQQEKHKLLEARTQFD 613

Query: 902  DLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLE 961
            +  S L     + Q  +V++K+ +E L   FN + E+  RD K      EK  E +    
Sbjct: 614  NRVSLLSARFKQKQAELVKQKQSLEQLTAAFNKEQEAVERDWKDRLANLEKQKEMLGDKV 673

Query: 962  AQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQK 1021
             Q  E   NI       E   K   + ++   QKQ +   +       +++KL+  LK +
Sbjct: 674  HQFDENSLNISKKLAERELAIKFKEKELEA-AQKQLSLDNNNNAGLKLQLDKLSESLKTE 732

Query: 1022 DEEIIALNQKINNAQVSYMSMVSDYES----KLAQFTTKLENMEEEMQRVSKQL-LDSKQ 1076
              E+ A  ++I +        ++DYES    +LA+  T  +N +E   +  ++L +  ++
Sbjct: 733  RLELEASKERILDFYDESSRRIADYESDLQARLAEVKTLEKNQQETAAKSERELKVALEK 792

Query: 1077 HNEELQILVREQDDQIKELKETK--LTFEMNIPKTEGMIISSTIEPM-------SDDANN 1127
             N+  +  ++ +  Q+ E+   K  L  + N+ K +   +    E +         D   
Sbjct: 793  LNQAKKAFLQIRKQQLLEIASVKQQLAQKANLLKNQQAELDKQTEELEAAFLEQDTDKKE 852

Query: 1128 VDXXXXXXXXXXXXLK------VQEEEEFIQERSVLQEQSAKLNTELQEC--YTKIIQLE 1179
            ++            L+      +Q++ EF +  +  + Q     T++Q    + K  Q E
Sbjct: 853  LEKALHSVKSKQELLERERSFLLQKQREFAEHVAGFKRQVHFKTTQMQRLSEFNKQQQSE 912

Query: 1180 TLNTE----LTGHDVVNQEQINQLKSKLE-QLNTENDNLLSTVAELRSSISSAVDQRGFE 1234
             +  E    +   D+    Q+ +L+   E Q   +    L  +A+ ++ +   ++Q+   
Sbjct: 913  QIKRETELKIAFADLKKDYQLFELQKNQEFQQIEQKHKELELLAQKQAELKQELEQKATA 972

Query: 1235 IAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTME-QVT 1293
            +A    Q   Q + D  + +HEL ++ +AF     Q   S+    ++ TN++  +  ++ 
Sbjct: 973  LAS-QDQDTVQAKLDLARQQHELELRQNAF----NQASLSLNKQREQLTNQVKVLHGELK 1027

Query: 1294 SLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLR 1353
                KL  K+  L   ++       +I     + E+E   F                +L 
Sbjct: 1028 KRHEKLTLKDRLLAEKEKDQHKKDAEINQRFKQFENEYADFDQAKKRELQELNQIRRNLE 1087

Query: 1354 TENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVND--AEAKVLE-LTHQLE 1410
              N S  + + Q  L+     A L+K              ++ +   E K  +  + +  
Sbjct: 1088 QSNASLLKKRNQLTLDF----ALLRKVQHNTQTNRVQLNTQIKEFLLEKKNFQKASDEAA 1143

Query: 1411 LKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYE-KESELAILRLKMHEN 1469
            L+ + + ++   +   L  +    E +  Q +E++KR E    E   ++L + + K+ E 
Sbjct: 1144 LQKALLIKRLRSFASKLQLQR---EALAIQKLEFDKRDEQQKSEINNAKLQLEQFKL-EK 1199

Query: 1470 ANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQ 1529
             N  E  QK+  IE     + L+V+         Q+  L+K+      + +  Q  L+++
Sbjct: 1200 QNFDEAKQKQL-IEFKDQCQRLDVEKRLLKQKLVQLKNLSKSYLTYKNRADLSQQQLQHK 1258

Query: 1530 EIEIVTLNDEITNLQNMVRASSSKIQ-KHVSFASDTKQGRDEQL 1572
               ++ L +++   +  +      I  K   F S+ +Q + + L
Sbjct: 1259 YANLLELKEKLQTAKRALDKKHRAIYGKMAQFVSELRQEKKQLL 1302


>UniRef50_A5DD85 Cluster: Putative uncharacterized protein; n=1;
            Pichia guilliermondii|Rep: Putative uncharacterized
            protein - Pichia guilliermondii (Yeast) (Candida
            guilliermondii)
          Length = 1375

 Score =  124 bits (298), Expect = 3e-26
 Identities = 232/1199 (19%), Positives = 485/1199 (40%), Gaps = 97/1199 (8%)

Query: 471  NTEDVNEIAKVQEQLK----QELNDEIKDVNVKDLIEKLKSAEEQITQLND---EIDAAN 523
            N ED+NE+ +VQ + +    Q+L   +++V +  L  K+   E  ++Q  D   E++   
Sbjct: 43   NKEDLNELLRVQTEQRAEHIQQLERYVEEV-LSSLTGKVNDLESSLSQKIDKIAELEEKL 101

Query: 524  KNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQL 583
            K   +V      K  ++ K       ++     +  L  E + L +++   + +K  L  
Sbjct: 102  KRTEEVLDAELHKGTELPKLSQTAELIAGEGISLSSLYVEFNQLKKQLVFEKSQKAKLAS 161

Query: 584  HLVDYDSGRMIESDVYKKMIEMENLAETRLK----AISLLESQKFDLVQELHILQQKYDE 639
             L  +      +  V     E     E+ LK     + ++  +K +  +E+  L+    +
Sbjct: 162  QLESFVRELEEKKPVIASYQEQIQFYESSLKDMIGKVEVVRLEKAEADKEIRRLKSTLTD 221

Query: 640  VEDKLADISQLQSD---QVCSEIKSVHLEEQIDA-LS-ASKKELALVIENLKLDKEQLYG 694
             E+ L    +L  D   Q+C  +  + + +  +  LS A +K +  ++E    +KE  Y 
Sbjct: 222  HENSLVSSKKLCRDLGTQLCYYLIHLRIRDNDEEPLSLAERKAIDNILERSG-NKEAKYE 280

Query: 695  TIKDLENDKE--------DIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSK 746
            T  D+             ++  K +N ++   +L  KLE    E   +L +    E +  
Sbjct: 281  TDTDMLISSRLVEFGSIVELQQKNENLLKVVRELGKKLEAKDQEHNEQLESAAIEEAKEA 340

Query: 747  IQTQFG--------IDAKIQERDLYIENIE-------SELSKYKSRIC-----RLEESIA 786
            I T  G        ++A  +ERD  +  IE       S   +Y + +C     RL +S  
Sbjct: 341  IITLEGEIDSLHIKLNAVTKERD-QLRTIERTNPSGSSSEVRYLNEVCDDLRKRLSQSEK 399

Query: 787  VMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEH 846
             + + + S  ++ ++L + L E+     E  I+ +  V+ + +       ++K L   + 
Sbjct: 400  NLREAQESSAQRINELNTRLNEEATQRGELLIKVNTQVHAVEMAEVRYSNLQKLLKNCKE 459

Query: 847  ENKELQ-----------KKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTK 895
            E K+L+           K+  +L+ +   L  + S++ ++   +       D+A S    
Sbjct: 460  ELKQLKSDIAFWKEQASKQEALLIRKANELSDATSELSKNQAIINGLRTEKDMAISLQGS 519

Query: 896  YQTQ---LRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEK 952
             + +   LR  +SNL       Q+L+ +++    ++    N  +E+    ++ L+E+ +K
Sbjct: 520  LRDEVASLRSDKSNLSLFVSNLQSLLKEREASNAEISSRLNQAVENYQSLQERLSERDDK 579

Query: 953  NIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKH--VQKQQTQSPDYTEQYINE 1010
                 TQ E +L+     +E ++   ++L +    L +K   V+K ++Q+ ++   + N 
Sbjct: 580  ITMLTTQAELELKSQYIKLEQVSDLSQKLAEARSSLAEKTALVEKLRSQTSNHESSFQNA 639

Query: 1011 INKLNALLKQKDEEIIALNQ-KINNAQVS-YMSMVSDYESKLAQFTTKLENMEEEMQRVS 1068
            + +        D +       ++   QV  + S+ ++ E  L   T   E  + + +   
Sbjct: 640  LLQAQVASTNGDADESRFEALRLAEQQVQEFSSIANNAEKALMDATASFEQFKTDHEHKV 699

Query: 1069 KQLLDSK-QHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANN 1127
             +L D + Q  +E++ L  E     +E  +        +      ++ + ++  S D   
Sbjct: 700  TELNDMRSQQQKEIERLSNEIQSANEERSKMTSQHMDEVQSLNSKLLEAIVKANSFDTMK 759

Query: 1128 VDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTG 1187
             D            L+ QE      ER +     +K + E +E  +   Q+ +LN EL+ 
Sbjct: 760  QDYETRLLSLRAD-LETQEARNADLERRLKDTADSKESLE-KEISSLRDQVNSLNEELSN 817

Query: 1188 HDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAEL------WKQ 1241
              +  ++  N+L +  EQ      NL  +  +LRS +SSA +Q    + +L       K 
Sbjct: 818  AKIALEDHNNELSNTAEQRAVALRNLQESFDDLRSKLSSAEEQNAILLNQLELNADNSKS 877

Query: 1242 HLAQRE-ADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQ 1300
               Q +  D       LR +  + E+K   L + V +   +  +  + +E   S   + Q
Sbjct: 878  SPDQADNQDLSSVVRYLRHEKESAEAKVVTLTEQVNTLRLKLEHTNLELEARNSELLRSQ 937

Query: 1301 DKEEHLRNLQEKYADVINQIE---ILR---------SEIEDEKVAFXXXXXXXXXXXXXX 1348
                 L +  +++  V+ Q+E   ILR         + I+ ++++               
Sbjct: 938  KATIELDSTNQEHLKVLEQLEQLNILRESNTTLRNENRIQAKRLSELEQQLNDVSNSLAT 997

Query: 1349 XXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQ 1408
                 T++      ++Q I  + EENA++K  +             V   + +   L ++
Sbjct: 998  IQVSLTQDAEKDDEKDQKIRLLEEENARIK--ANMSQTSTADNSEEVEALKKRFTNLKNE 1055

Query: 1409 LELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHE 1468
             + K      KT E    +     E ++  ++++E EK+      +K+        K+  
Sbjct: 1056 FQNKLLVHRGKTKELEKVVENLRSELKS-NKKMLEDEKKSRQEVVDKQPNNEEGEQKLKA 1114

Query: 1469 NANHYETMQKESEIERVKLIEELNV---KITESVSLNKQVAELNKALEE---EVAKTNEM 1522
              +  E   KE E+E+VKL  +L V       +VS++ +V ++   LE+   EV K+   
Sbjct: 1115 LRDESEKRIKELELEKVKLEAQLQVLQKSGASNVSVSDEVEKVRGQLEKEKAEVEKSFSE 1174

Query: 1523 QTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFA-SDTKQGRDEQLDNTMNKEL 1580
            +  L  ++IE +  +   +N++ ++   + K  K +  A    KQ  ++Q D  +  E+
Sbjct: 1175 KLKLAEEQIEALKRDSSNSNVEQLLAQEAEKQNKKLEEALQSRKQELEKQFDERLQTEI 1233



 Score = 89.4 bits (212), Expect = 7e-16
 Identities = 128/632 (20%), Positives = 285/632 (45%), Gaps = 46/632 (7%)

Query: 503  EKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTE 562
            E L+ AE+Q+ + +   + A K ++   ++ +      Q   D+  KV++ N    +  +
Sbjct: 658  EALRLAEQQVQEFSSIANNAEKALMDATASFE------QFKTDHEHKVTELNDMRSQQQK 711

Query: 563  ELHHLSQKVAELEEEKGNL-QLHLVDYDS--GRMIESDVYKKMIE-MENLAETRLKAISL 618
            E+  LS ++    EE+  +   H+ +  S   +++E+ V     + M+   ETRL ++  
Sbjct: 712  EIERLSNEIQSANEERSKMTSQHMDEVQSLNSKLLEAIVKANSFDTMKQDYETRLLSLRA 771

Query: 619  -LESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCS---EIKS--VHLEEQIDALS 672
             LE+Q+         L+   D  E    +IS L+ DQV S   E+ +  + LE+  + LS
Sbjct: 772  DLETQEARNADLERRLKDTADSKESLEKEISSLR-DQVNSLNEELSNAKIALEDHNNELS 830

Query: 673  ASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKI 732
             + ++ A+ + NL+   + L   +   E     ++N+L+     +    D+ +    + +
Sbjct: 831  NTAEQRAVALRNLQESFDDLRSKLSSAEEQNAILLNQLELNADNSKSSPDQADN---QDL 887

Query: 733  SELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMED-- 790
            S ++  + HE++S       +  ++    L +E+   EL    S + R +++   ++   
Sbjct: 888  SSVVRYLRHEKESAEAKVVTLTEQVNTLRLKLEHTNLELEARNSELLRSQKATIELDSTN 947

Query: 791  -RRYSLERKADQLGSYLQEKQKAYSEYTIQE---DELVNRLAVLMDHDRVVEKQLLEIEH 846
                 +  + +QL    +      +E  IQ     EL  +L  + +    ++  L +   
Sbjct: 948  QEHLKVLEQLEQLNILRESNTTLRNENRIQAKRLSELEQQLNDVSNSLATIQVSLTQDAE 1007

Query: 847  ENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESN 906
            ++ E  +K ++L EEN  ++ ++S      N+   +A +      ++ ++Q +L      
Sbjct: 1008 KDDEKDQKIRLLEEENARIKANMSQTSTADNSEEVEALKKRFTNLKN-EFQNKLLVHRGK 1066

Query: 907  LKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVT-QLEAQLQ 965
             K +    + L  + K   + LE E  ++ E  + DK+  NE+ E+ ++ +  + E +++
Sbjct: 1067 TKELEKVVENLRSELKSNKKMLEDEKKSRQE--VVDKQPNNEEGEQKLKALRDESEKRIK 1124

Query: 966  EYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINK-LNALLKQKDEE 1024
            E +     L   ++ L K     +    + ++ +     E+   E+ K  +  LK  +E+
Sbjct: 1125 ELELEKVKLEAQLQVLQKSGASNVSVSDEVEKVRGQ--LEKEKAEVEKSFSEKLKLAEEQ 1182

Query: 1025 IIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLL----DSKQHN-- 1078
            I AL +  +N+ V  + +  + E +  +    L++ ++E+++   + L    +S+Q N  
Sbjct: 1183 IEALKRDSSNSNVEQL-LAQEAEKQNKKLEEALQSRKQELEKQFDERLQTEIESRQQNIS 1241

Query: 1079 ---EELQILVREQDDQIKELK---ETKLTFEM 1104
                  + LV++ + QI+ELK   E +LT E+
Sbjct: 1242 GGDSSSEELVKKYESQIEELKQDFEKRLTTEI 1273



 Score = 84.6 bits (200), Expect = 2e-14
 Identities = 168/909 (18%), Positives = 358/909 (39%), Gaps = 77/909 (8%)

Query: 705  DIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYI 764
            ++  +L++   + + L  K E    +   +L  K +  E  ++QT+   +  IQ+ + Y+
Sbjct: 11   NLQAELESQTSKLLSLDSKFEVEKIKYAKDLKNKEDLNELLRVQTEQRAE-HIQQLERYV 69

Query: 765  ENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELV 824
            E + S L+               + D   SL +K D++   L+EK K   E    E    
Sbjct: 70   EEVLSSLT-------------GKVNDLESSLSQKIDKIAE-LEEKLKRTEEVLDAELHKG 115

Query: 825  NRLAVLMDHDRVVEKQLLEIEHENKEL-QKKNQILLEENQNLQISLSDMQQHYNALVEKA 883
              L  L     ++  + + +     E  Q K Q++ E++Q  +++ S ++     L EK 
Sbjct: 116  TELPKLSQTAELIAGEGISLSSLYVEFNQLKKQLVFEKSQKAKLA-SQLESFVRELEEK- 173

Query: 884  NRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKK---KEIEDLEIEFNTQIESAI 940
                  +     YQ Q++  ES+LK +  + + + ++K    KEI  L+        S +
Sbjct: 174  ------KPVIASYQEQIQFYESSLKDMIGKVEVVRLEKAEADKEIRRLKSTLTDHENSLV 227

Query: 941  RDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQS 1000
              KK+  +           L  QL  Y  ++   + + E L+    + ID  +++    S
Sbjct: 228  SSKKLCRD-----------LGTQLCYYLIHLRIRDNDEEPLSLAERKAIDNILER----S 272

Query: 1001 PDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENM 1060
             +   +Y  + + L +    +   I+ L QK  N       +    E+K  +   +LE+ 
Sbjct: 273  GNKEAKYETDTDMLISSRLVEFGSIVELQQKNENLLKVVRELGKKLEAKDQEHNEQLESA 332

Query: 1061 EEEMQRVSKQLLDSKQHNEELQI-LVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIE 1119
              E  + +   L+ +  +  +++  V ++ DQ++ ++ T  +   +  +    +     +
Sbjct: 333  AIEEAKEAIITLEGEIDSLHIKLNAVTKERDQLRTIERTNPSGSSSEVRYLNEVCDDLRK 392

Query: 1120 PMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLE 1179
             +S    N+             L  +  EE  Q   +L     K+NT++       ++  
Sbjct: 393  RLSQSEKNLREAQESSAQRINELNTRLNEEATQRGELL----IKVNTQVHAVEMAEVRYS 448

Query: 1180 TLNTELTGHDVVNQEQINQLKSKL----EQLNTENDNLLSTVAELRSSISS-AVDQRGFE 1234
             L   L       +E++ QLKS +    EQ + +   L+    EL  + S  + +Q    
Sbjct: 449  NLQKLLKNC----KEELKQLKSDIAFWKEQASKQEALLIRKANELSDATSELSKNQAIIN 504

Query: 1235 IAELWKQHLAQREADFQKTEHELRVQ---LSAFESKYEQLLDSVQSSTQEETNKI-VTME 1290
                 K      +   +     LR     LS F S  + LL   ++S  E ++++   +E
Sbjct: 505  GLRTEKDMAISLQGSLRDEVASLRSDKSNLSLFVSNLQSLLKEREASNAEISSRLNQAVE 564

Query: 1291 QVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXX 1350
               SLQ +L ++++ +  L  + A++  + + ++ E   +                    
Sbjct: 565  NYQSLQERLSERDDKITMLTTQ-AELELKSQYIKLEQVSDLSQKLAEARSSLAEKTALVE 623

Query: 1351 DLRTENQSYKQMQEQSILN--INEENAQLKKSSXXXXXXXXXXXXR----VNDAEAKVLE 1404
             LR++  +++   + ++L   +   N    +S                   N+AE  +++
Sbjct: 624  KLRSQTSNHESSFQNALLQAQVASTNGDADESRFEALRLAEQQVQEFSSIANNAEKALMD 683

Query: 1405 LTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRL 1464
             T   E   ++   K  E     +Q+  E E +  ++    +    +T +   E+  L  
Sbjct: 684  ATASFEQFKTDHEHKVTELNDMRSQQQKEIERLSNEIQSANEERSKMTSQHMDEVQSLNS 743

Query: 1465 KMHE---NANHYETMQKESEIERVKLIEELNVKITESVSLN---KQVAELNKALEEEVA- 1517
            K+ E    AN ++TM+++ E   + L  +L  +   +  L    K  A+  ++LE+E++ 
Sbjct: 744  KLLEAIVKANSFDTMKQDYETRLLSLRADLETQEARNADLERRLKDTADSKESLEKEISS 803

Query: 1518 ---KTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDN 1574
               + N +   L N +I +   N+E++N       +   +Q+            +EQ   
Sbjct: 804  LRDQVNSLNEELSNAKIALEDHNNELSNTAEQRAVALRNLQESFDDLRSKLSSAEEQNAI 863

Query: 1575 TMNKELLDA 1583
             +N+  L+A
Sbjct: 864  LLNQLELNA 872



 Score = 84.6 bits (200), Expect = 2e-14
 Identities = 167/868 (19%), Positives = 353/868 (40%), Gaps = 76/868 (8%)

Query: 156  NALSVLQVKMKIMETTILDLQEKINE-KDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDT 214
            +A+ + +V+   ++  + + +E++ + K  I   K +A+                  E +
Sbjct: 438  HAVEMAEVRYSNLQKLLKNCKEELKQLKSDIAFWKEQASKQEALLIRKANELSDATSELS 497

Query: 215  KQQ-----MTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISL 269
            K Q     +   ++  I+++   +DE   L  D  +  + +S+L+   K  EA+  EIS 
Sbjct: 498  KNQAIINGLRTEKDMAISLQGSLRDEVASLRSDKSNLSLFVSNLQSLLKEREASNAEIS- 556

Query: 270  EHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTE---IEEKGSL--EIANM-TE 323
              S+L Q +E               +   + +   E K++   +E+   L  ++A   + 
Sbjct: 557  --SRLNQAVENYQSLQERLSERDDKITMLTTQAELELKSQYIKLEQVSDLSQKLAEARSS 614

Query: 324  LTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPL-ISRKSGRNTASKM 382
            L +K  L+E L  Q        +N L      S    +   +   L ++ +  +  +S  
Sbjct: 615  LAEKTALVEKLRSQTSNHESSFQNALLQAQVASTNGDADESRFEALRLAEQQVQEFSSIA 674

Query: 383  KSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXX 442
             +    L   T + +  K  +++++ +L  +     K++      I   +          
Sbjct: 675  NNAEKALMDATASFEQFKTDHEHKVTELNDMRSQQQKEIERLSNEIQSANEERSKMTSQH 734

Query: 443  XGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIA--KVQEQLKQELNDEIKDV-NVK 499
              +   +    LE          +     T  ++  A  + QE    +L   +KD  + K
Sbjct: 735  MDEVQSLNSKLLEAIVKANSFDTMKQDYETRLLSLRADLETQEARNADLERRLKDTADSK 794

Query: 500  DLIEK-LKSAEEQITQLNDEIDAA-------NKNMIKVKSNHKLKLKQMQKTIDNF-SKV 550
            + +EK + S  +Q+  LN+E+  A       N  +        + L+ +Q++ D+  SK+
Sbjct: 795  ESLEKEISSLRDQVNSLNEELSNAKIALEDHNNELSNTAEQRAVALRNLQESFDDLRSKL 854

Query: 551  SDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYK--KMIEMENL 608
            S + ++   L  +L   +       ++  N  L  V        ES   K   + E  N 
Sbjct: 855  SSAEEQNAILLNQLELNADNSKSSPDQADNQDLSSVVRYLRHEKESAEAKVVTLTEQVNT 914

Query: 609  AETRLKAISL-LESQKFDLVQ------ELHILQQKYDEVEDKLADISQLQSDQVC----S 657
               +L+  +L LE++  +L++      EL    Q++ +V ++L  ++ L+         +
Sbjct: 915  LRLKLEHTNLELEARNSELLRSQKATIELDSTNQEHLKVLEQLEQLNILRESNTTLRNEN 974

Query: 658  EIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNY-IQE 716
             I++  L E    L+     LA +  +L  D E      KD E D++  + + +N  I+ 
Sbjct: 975  RIQAKRLSELEQQLNDVSNSLATIQVSLTQDAE------KDDEKDQKIRLLEEENARIKA 1028

Query: 717  NMDLTDKLEKMS-AEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYK 775
            NM  T   +     E + +    + +E Q+K+    G   K +E +  +EN+ SEL   K
Sbjct: 1029 NMSQTSTADNSEEVEALKKRFTNLKNEFQNKLLVHRG---KTKELEKVVENLRSELKSNK 1085

Query: 776  SRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDR 835
              +   ++S   + D++ + E    +L +   E +K   E  +++ +L  +L VL     
Sbjct: 1086 KMLEDEKKSRQEVVDKQPNNEEGEQKLKALRDESEKRIKELELEKVKLEAQLQVLQKSGA 1145

Query: 836  V-------VEKQLLEIEHENKELQKK--NQILLEE-----------NQNLQISLSDMQQH 875
                    VEK   ++E E  E++K    ++ L E           N N++  L+   + 
Sbjct: 1146 SNVSVSDEVEKVRGQLEKEKAEVEKSFSEKLKLAEEQIEALKRDSSNSNVEQLLAQEAEK 1205

Query: 876  YNALVEKA---NRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEF 932
             N  +E+A    + +L +    + QT++   + N+       + L+ + + +IE+L+ +F
Sbjct: 1206 QNKKLEEALQSRKQELEKQFDERLQTEIESRQQNISGGDSSSEELVKKYESQIEELKQDF 1265

Query: 933  NTQIESAIRD-KKVLNEKYEKNIEYVTQ 959
              ++ + I D KK   +K+E  +  + +
Sbjct: 1266 EKRLTTEIEDIKKKTEKKFEIKVRMLNK 1293


>UniRef50_UPI000051A547 Cluster: PREDICTED: similar to CG6129-PB,
            isoform B; n=3; Endopterygota|Rep: PREDICTED: similar to
            CG6129-PB, isoform B - Apis mellifera
          Length = 2052

 Score =  123 bits (297), Expect = 4e-26
 Identities = 279/1312 (21%), Positives = 564/1312 (42%), Gaps = 134/1312 (10%)

Query: 327  KIELLEHLNCQIR-QTNKE-LENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKS 384
            K +L  H   Q++ QTNKE L+N         + V +  KK   LI           ++ 
Sbjct: 524  KYQLTIH-ELQVKLQTNKEQLQNTRKQCENAEENVKTLEKKAEELIIELDA------VRL 576

Query: 385  PWSQLSSET--LNQDTDK-KINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXX 441
              SQL+ E   L +  D  +I KN + K  + + ++ ++L + +    +K          
Sbjct: 577  HCSQLNQEKDMLQKGLDTIRIEKNTLEKTRIELNNMMENL-NNDCEKLQKANNKLQKICD 635

Query: 442  XXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQL---KQELNDEIKDVNV 498
                + L  Q +L      +   L  +   +E+ +  +K++E+L   ++ELN   K    
Sbjct: 636  NLEDEKLYLQSELNRLS--KDVELRELNLRSEE-DRCSKMREELLTLREELN---KTYLS 689

Query: 499  KDLIEKLKSAEE----QITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDS- 553
            KD++E+ K   +    QI +   +++   + ++  KS+ +  L +++    N  +     
Sbjct: 690  KDMLEQQKLETDGLISQIEKSKGDLELELERVLLEKSDVQEVLMKLETVCSNHEQEKQRL 749

Query: 554  NKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRM-IESD------------VYK 600
             +E+ ++TEE + L+ +  + + + G+L+  L+  +  R+ +ES+            + K
Sbjct: 750  QEELKKVTEEKNKLANQCTDQQGDLGSLRKELLQAEQTRLDLESEKVTLNEKVKFLEIEK 809

Query: 601  KMIEMENLAETRLKA-----ISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQV 655
            + IE+E    TR +      +S+L  +K  L +EL  L+Q+ ++  +    I++   D V
Sbjct: 810  EKIEIELAQVTRERGDFNNQLSVLARKKETLNEELMRLKQRLEQANEMNGRINRNLEDLV 869

Query: 656  C-SEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYI 714
              +E K V LE     +   +++LA    +++ +KE L G + D +   E++  K     
Sbjct: 870  KDNEEKQVLLETNEKEVQRLQEQLA----SMRSEKETLEGVLFDTQTSLENMHVKKTQLE 925

Query: 715  QENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKY 774
            +E  +L  K E +  + +  L+  + + E+   + +  +  +  +++   + I S + K+
Sbjct: 926  KEQKELLIKQESLKGQ-VERLMKDLENSEKRIHEVKQTLTQQSGDQEAEFQQIISNVKKH 984

Query: 775  -KSRICRLEESIAVMEDRRYSLERKADQ-LGSYLQEKQKAYSEYTIQEDELVNRLAVLMD 832
             +  I +L E     E  + +LE++  Q L     EK    ++   + DE+   +  L  
Sbjct: 985  SEENIKKLNEE---KEQIKINLEKRLQQSLLQVTGEKDNEINQLQQRIDEMQQHIENLCQ 1041

Query: 833  HDRVVEKQLLEIEHENKEL----QKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDL 888
                 E+ LL  E++ ++         Q L+E+   L+  L +M++  N  VE+  R   
Sbjct: 1042 QH---EEVLLRAENDKQQALLIAHHDQQALMEK---LETVLHEMEEEKNN-VERVKREAA 1094

Query: 889  AESESTKYQ-TQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIE-FNTQIESAIRDKKVL 946
             ++E  +    QLRD  + LK    E +    ++K ++ DL+IE    + E A R+ + L
Sbjct: 1095 VKTEQERNNINQLRDELNRLKTKLDETRLKTDEEKIKL-DLKIEELWKERELAQRESEEL 1153

Query: 947  NEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQ 1006
              +     + V  L+ QL E    +++     E L K   EL+D  +++Q   S    E+
Sbjct: 1154 QVQLHMTEDKVDSLQNQLHETIRKLKDAENLNETLRK---ELVD--IRRQLGDSTYEKEK 1208

Query: 1007 YINEINKLNALLKQKDEEIIALNQKINNA--QVSYMS-MVSDYESKLAQFTTKLENMEEE 1063
            Y +   +L   +K+ + E    N+ +  +  ++S +  M  + +++ ++   ++ +ME+E
Sbjct: 1209 YNSSNKELREHVKRIESEKREQNRILEESYQKISALEDMKVNVDAERSRLQAQIRDMEKE 1268

Query: 1064 MQRVSKQL-LDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMS 1122
            M ++ KQL     +  +  Q   + Q+D+ KEL + +LT E      E   +   +  + 
Sbjct: 1269 MLQLQKQLHFTQDELQKSHQSNAQAQNDE-KEL-QARLTNETE----ERERLQLQLHQVK 1322

Query: 1123 DDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLN 1182
                +VD            L+ + +EE   ER  ++EQ   +  E   C  + ++ +  N
Sbjct: 1323 KQLMDVDNSLKVTRQELGRLRSRADEE--NERWRVREQELVVRLEDSRCRERKLEDQKHN 1380

Query: 1183 TELTGHDVVNQEQINQLKSKL-------EQLNTENDNLLSTVAELRSSISSAVDQRGFEI 1235
             E+   D    +QI +LK++L         L+ +   L  T  E+   +SS V      I
Sbjct: 1381 LEVCLADA--SQQIQELKARLGGSEGRVRALDAQLSQLEITKKEVEQKLSS-VGSTLRRI 1437

Query: 1236 AELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVT--MEQVT 1293
            A +                          +   +   D +     E   K V   M+QV 
Sbjct: 1438 AGIQMDGSVNIPFKLLSPSRRWSPARGTSQDHIDSSRDVILDVDPEIIRKGVRSLMQQVA 1497

Query: 1294 SLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLR 1353
             ++ +  D +  L NL+++  +  NQ    RS+I+   +                     
Sbjct: 1498 QIERERDDYKTELCNLKKQLDE--NQEIQNRSDIQINTLLTNIRMLQDEKNSLEVKL--- 1552

Query: 1354 TENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKD 1413
            ++ QS  +MQ  ++   +EE  QL++                N++E K+     Q E K 
Sbjct: 1553 SQKQSGYEMQLNALQLKSEECEQLREKIINLELMIS------NNSEEKI-----QFEEKL 1601

Query: 1414 SEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEK---ESELAILRLKMHENA 1470
             ++ Q        L +  +E  N++++L + E R   L  ++   E +L  L++   E  
Sbjct: 1602 DKLKQ-------VLNKVENEKRNLQEELSKSESRATKLELQRMSLEGDLQRLQMMFQEKD 1654

Query: 1471 NHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQE 1530
             +   +Q+ ++ +  + +  L  + T   SL   V +LN ALE+     NE++  + + +
Sbjct: 1655 ANIHKLQERNDTQN-RTMTTLEERCT---SLKSMVEQLNLALEKASTTENELKNEINSMQ 1710

Query: 1531 IEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLD 1582
              I+ L    T LQ      + ++QK +S A + ++   E+++ +M + L D
Sbjct: 1711 HNIMELT---TTLQTS-NEKNKQLQKQISNAENERRILSERIE-SMQQSLND 1757



 Score =  118 bits (285), Expect = 1e-24
 Identities = 255/1316 (19%), Positives = 546/1316 (41%), Gaps = 108/1316 (8%)

Query: 235  EKQRLLKDIESKDVR--ISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXX 292
            E +R+L  +E  DV+  +  LE      E  +  +  E  K+ +E  +            
Sbjct: 717  ELERVL--LEKSDVQEVLMKLETVCSNHEQEKQRLQEELKKVTEEKNKLANQCTDQQGDL 774

Query: 293  XXLAKQSIEPSCEEKTEIE-EKGSL-EIANMTELTKKIELLEHLNCQIRQTNKELENKLA 350
              L K+ ++   + + ++E EK +L E     E+ K  E +E    Q+ +   +  N+L+
Sbjct: 775  GSLRKELLQAE-QTRLDLESEKVTLNEKVKFLEIEK--EKIEIELAQVTRERGDFNNQLS 831

Query: 351  TMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKI----NKNE 406
             +  + + ++        L+  K     A++M    ++   + +  + +K++    N+ E
Sbjct: 832  VLARKKETLNEE------LMRLKQRLEQANEMNGRINRNLEDLVKDNEEKQVLLETNEKE 885

Query: 407  IAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLI 466
            + +L+  + S+  +    E V+ +  T            +    +L ++ Q+ ++G    
Sbjct: 886  VQRLQEQLASMRSEKETLEGVLFDTQTSLENMHVKKTQLEKEQKELLIK-QESLKGQVER 944

Query: 467  HVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKS-AEEQITQLNDEIDAANKN 525
             +         I +V++ L Q+  D+  +   + +I  +K  +EE I +LN+E     K 
Sbjct: 945  LMKDLENSEKRIHEVKQTLTQQSGDQ--EAEFQQIISNVKKHSEENIKKLNEE-----KE 997

Query: 526  MIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAE--LEEEKGNLQL 583
             IK+    +L+   +Q T +  ++++   + I  + + + +L Q+  E  L  E    Q 
Sbjct: 998  QIKINLEKRLQQSLLQVTGEKDNEINQLQQRIDEMQQHIENLCQQHEEVLLRAENDKQQA 1057

Query: 584  HLVDYDSGRMIESDVYKKMIEME----NLAETRLKAISLLESQKFDLVQ---ELHILQQK 636
             L+ +   + +   +   + EME    N+   + +A    E ++ ++ Q   EL+ L+ K
Sbjct: 1058 LLIAHHDQQALMEKLETVLHEMEEEKNNVERVKREAAVKTEQERNNINQLRDELNRLKTK 1117

Query: 637  YDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLD--KEQLYG 694
             DE   K  D  +++ D    +I+ +  E ++    + + ++ L +   K+D  + QL+ 
Sbjct: 1118 LDETRLK-TDEEKIKLDL---KIEELWKERELAQRESEELQVQLHMTEDKVDSLQNQLHE 1173

Query: 695  TI---KDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQF 751
            TI   KD EN  E +  +L +  ++  D T + EK ++    EL   +   E  K +   
Sbjct: 1174 TIRKLKDAENLNETLRKELVDIRRQLGDSTYEKEKYNSSN-KELREHVKRIESEKREQNR 1232

Query: 752  GIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQK 811
             ++   Q+    +E+++  +   +SR   L+  I  ME     L+++       LQ+  +
Sbjct: 1233 ILEESYQKISA-LEDMKVNVDAERSR---LQAQIRDMEKEMLQLQKQLHFTQDELQKSHQ 1288

Query: 812  AYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSD 871
            + ++    E EL  RL      +   E++ L+++      Q K Q L++ + +L+++  +
Sbjct: 1289 SNAQAQNDEKELQARLT-----NETEERERLQLQLH----QVKKQ-LMDVDNSLKVTRQE 1338

Query: 872  MQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIE 931
            + +  +   E+  R  + E E        R  E  L+   H  +  +    ++I++L+  
Sbjct: 1339 LGRLRSRADEENERWRVREQELVVRLEDSRCRERKLEDQKHNLEVCLADASQQIQELKAR 1398

Query: 932  FNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDK 991
                 E  +R       + E   + V Q  + +      I  + M+      +N+    K
Sbjct: 1399 LGGS-EGRVRALDAQLSQLEITKKEVEQKLSSVGSTLRRIAGIQMD----GSVNIPF--K 1451

Query: 992  HVQKQQTQSPDY-TEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMV-SDYESK 1049
             +   +  SP   T Q  + I+    ++   D EII    +    QV+ +     DY+++
Sbjct: 1452 LLSPSRRWSPARGTSQ--DHIDSSRDVILDVDPEIIRKGVRSLMQQVAQIERERDDYKTE 1509

Query: 1050 LAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKT 1109
            L     +L+   +E+Q  S   +++   N  +++L  E++    +L + +  +EM +   
Sbjct: 1510 LCNLKKQLDE-NQEIQNRSDIQINTLLTN--IRMLQDEKNSLEVKLSQKQSGYEMQLNAL 1566

Query: 1110 EGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVL---QEQSAKLNT 1166
            +  + S   E + +   N++             K+Q EE+  + + VL   + +   L  
Sbjct: 1567 Q--LKSEECEQLREKIINLELMISNNSEE----KIQFEEKLDKLKQVLNKVENEKRNLQE 1620

Query: 1167 ELQECYTKIIQLETLNTELTGHDVVNQEQINQLKS----KLEQLNTENDNLLSTVAELRS 1222
            EL +  ++  +LE     L G D+   + + Q K     KL++ N   +  ++T+ E  +
Sbjct: 1621 ELSKSESRATKLELQRMSLEG-DLQRLQMMFQEKDANIHKLQERNDTQNRTMTTLEERCT 1679

Query: 1223 SISSAVDQRGF--EIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQ 1280
            S+ S V+Q     E A   +  L       Q    EL   L     K +QL   + ++  
Sbjct: 1680 SLKSMVEQLNLALEKASTTENELKNEINSMQHNIMELTTTLQTSNEKNKQLQKQISNA-- 1737

Query: 1281 EETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXX 1340
             E  + +  E++ S+Q  L D    L++  +   D I +++   +  E ++ A       
Sbjct: 1738 -ENERRILSERIESMQQSLND----LKHTNQTLTDQITRLQNELANNEVQRCALESQLRI 1792

Query: 1341 XXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEA 1400
                      ++  + +  +Q+Q   I        + K  +            R  + + 
Sbjct: 1793 VAYPTQEE--NINKDEELLRQLQ---IAQRERSEMRGKMEALNDKMKLLEADKRNLERQL 1847

Query: 1401 KVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELA 1460
             + + T++   K  E Y+K H   +  +   D +E   ++L    +R+E    EKE+EL 
Sbjct: 1848 SLFKSTNRS--KSYERYEKAHTELLGTSFDIDHYEQENRELRLKVRRLETQLAEKEAELI 1905

Query: 1461 ILRLK-MHENANHYETMQKESEIERVKLIEELNVKITES--VSLNKQVAELNKALE 1513
             L+    H ++       +  EIER++  +    K+ E+   S  +QV  L   ++
Sbjct: 1906 RLKSSYTHTHSVFDFNRDRTGEIERLRAAQLQAEKLLEAREQSHRQQVLRLENQIQ 1961



 Score = 97.9 bits (233), Expect = 2e-18
 Identities = 178/969 (18%), Positives = 402/969 (41%), Gaps = 81/969 (8%)

Query: 625  DLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVH-LEEQIDALSASKKELALVIE 683
            DL  EL  L+Q+YD  ++++    +++ +++   I+ VH LEE+             + +
Sbjct: 396  DLKTELITLKQQYDVAQNEI----RIKEEKINQLIRDVHSLEERCGEAETEIHRNTRLQD 451

Query: 684  NLKLDKEQLYGTIKDLENDKEDI-MNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHE 742
            ++++ +  L      +  D E   +   Q     ++  T  + + S ++ +    + N  
Sbjct: 452  DIEILQSALRDIAHAVIQDAESREIESTQAPPHLHLSPTGPIPQKSPKRGT----RSNTI 507

Query: 743  EQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQL 802
                  T   + A + +  L I  ++ +L   K ++    +     E+   +LE+KA++L
Sbjct: 508  PAFAESTISAVQAALHKYQLTIHELQVKLQTNKEQLQNTRKQCENAEENVKTLEKKAEEL 567

Query: 803  GSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEEN 862
               L   +   S+   ++D L   L  +      +EK  +E+ +  + L    + L + N
Sbjct: 568  IIELDAVRLHCSQLNQEKDMLQKGLDTIRIEKNTLEKTRIELNNMMENLNNDCEKLQKAN 627

Query: 863  QNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKK 922
              LQ    +++     L  + NR             +LR+L  NL+      +    + +
Sbjct: 628  NKLQKICDNLEDEKLYLQSELNR--------LSKDVELREL--NLR----SEEDRCSKMR 673

Query: 923  KEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELN 982
            +E+  L  E N    S    K +L ++  +    ++Q+E    + +  +E + +   ++ 
Sbjct: 674  EELLTLREELNKTYLS----KDMLEQQKLETDGLISQIEKSKGDLELELERVLLEKSDVQ 729

Query: 983  K--MNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYM 1040
            +  M LE +  + ++++ +  +  ++   E NKL      +  ++ +L +++  A+ + +
Sbjct: 730  EVLMKLETVCSNHEQEKQRLQEELKKVTEEKNKLANQCTDQQGDLGSLRKELLQAEQTRL 789

Query: 1041 SMVSD---YESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKE 1097
             + S+      K+     + E +E E+ +V+++  D    N +L +L R+++   +EL  
Sbjct: 790  DLESEKVTLNEKVKFLEIEKEKIEIELAQVTRERGD---FNNQLSVLARKKETLNEELMR 846

Query: 1098 TKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEE-EEFIQERSV 1156
             K   E    +  G  I+  +E +  D  N +             ++QE+      E+  
Sbjct: 847  LKQRLE-QANEMNGR-INRNLEDLVKD--NEEKQVLLETNEKEVQRLQEQLASMRSEKET 902

Query: 1157 LQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLST 1216
            L+       T L+  + K  QLE    EL    ++ QE    LK ++E+L  + +N    
Sbjct: 903  LEGVLFDTQTSLENMHVKKTQLEKEQKEL----LIKQE---SLKGQVERLMKDLENSEKR 955

Query: 1217 VAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQ 1276
            + E++ +++     +  E  ++        E + +K   E        E + +Q L  V 
Sbjct: 956  IHEVKQTLTQQSGDQEAEFQQIISNVKKHSEENIKKLNEEKEQIKINLEKRLQQSLLQV- 1014

Query: 1277 SSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXX 1336
              T E+ N      ++  LQ ++ + ++H+ NL +++ +V+ + E   ++ +   +    
Sbjct: 1015 --TGEKDN------EINQLQQRIDEMQQHIENLCQQHEEVLLRAE---NDKQQALLIAHH 1063

Query: 1337 XXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKK-SSXXXXXXXXXXXXRV 1395
                          ++  E  + ++++ ++ +   +E   + +               R+
Sbjct: 1064 DQQALMEKLETVLHEMEEEKNNVERVKREAAVKTEQERNNINQLRDELNRLKTKLDETRL 1123

Query: 1396 NDAEAKV-LELTHQLELKDSEIYQK-THEYTITLTQRNDEFENVRQQLVEYEKRIED--- 1450
               E K+ L+L  +   K+ E+ Q+ + E  + L    D+ ++++ QL E  ++++D   
Sbjct: 1124 KTDEEKIKLDLKIEELWKERELAQRESEELQVQLHMTEDKVDSLQNQLHETIRKLKDAEN 1183

Query: 1451 LTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNK 1510
            L      EL  +R ++ ++     T +KE      K + E +VK  ES     +  E N+
Sbjct: 1184 LNETLRKELVDIRRQLGDS-----TYEKEKYNSSNKELRE-HVKRIES-----EKREQNR 1232

Query: 1511 ALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDE 1570
             LEE   K + ++    N + E   L  +I +++        ++QK + F  D  Q   +
Sbjct: 1233 ILEESYQKISALEDMKVNVDAERSRLQAQIRDMEK----EMLQLQKQLHFTQDELQKSHQ 1288

Query: 1571 QLDNTMNKE 1579
                  N E
Sbjct: 1289 SNAQAQNDE 1297



 Score = 96.7 bits (230), Expect = 5e-18
 Identities = 275/1444 (19%), Positives = 573/1444 (39%), Gaps = 124/1444 (8%)

Query: 147  LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXX 206
            L NT K+ +NA   ++   K  E  I++L        Q+ + K+                
Sbjct: 543  LQNTRKQCENAEENVKTLEKKAEELIIELDAVRLHCSQLNQEKDMLQKGLDTIRIEKNTL 602

Query: 207  XXXXXEDTKQQMTKMQENF---IAMEAEWKDEKQRLLKDIESKDVRISS-LEEANKLLEA 262
                 E T+ ++  M EN         +  ++ Q++  ++E + + + S L   +K +E 
Sbjct: 603  -----EKTRIELNNMMENLNNDCEKLQKANNKLQKICDNLEDEKLYLQSELNRLSKDVEL 657

Query: 263  ARFEISLEH---SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIA 319
                +  E    SK+ +EL                L +Q +E         + KG LE+ 
Sbjct: 658  RELNLRSEEDRCSKMREELLTLREELNKTYLSKDMLEQQKLETDGLISQIEKSKGDLELE 717

Query: 320  NMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTA 379
                L +K ++ E L  ++       E +   +  E K V+    K +   + + G    
Sbjct: 718  LERVLLEKSDVQEVL-MKLETVCSNHEQEKQRLQEELKKVTEEKNKLANQCTDQQG--DL 774

Query: 380  SKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXX 439
              ++    Q     L+ +++K     ++  LE+  + +  +L     V  E+        
Sbjct: 775  GSLRKELLQAEQTRLDLESEKVTLNEKVKFLEIEKEKIEIELAQ---VTRERGDFNNQLS 831

Query: 440  XXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVN-V 498
                 K+TL  +L +  +Q +E  + ++ G    ++ ++ K  E+ +  L    K+V  +
Sbjct: 832  VLARKKETLNEEL-MRLKQRLEQANEMN-GRINRNLEDLVKDNEEKQVLLETNEKEVQRL 889

Query: 499  KDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIV 558
            ++ +  ++S +E +  +  +   + +NM  VK   K +L++ QK +    K      ++ 
Sbjct: 890  QEQLASMRSEKETLEGVLFDTQTSLENM-HVK---KTQLEKEQKEL--LIKQESLKGQVE 943

Query: 559  RLTEELHHLSQKVAE----LEEEKGNLQLHLVDYDSG--RMIESDVYKKMIEMENLA--- 609
            RL ++L +  +++ E    L ++ G+ +       S   +  E ++ K   E E +    
Sbjct: 944  RLMKDLENSEKRIHEVKQTLTQQSGDQEAEFQQIISNVKKHSEENIKKLNEEKEQIKINL 1003

Query: 610  ETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQID 669
            E RL+   L  + + D   E++ LQQ+ DE++  + ++ Q Q ++V    ++   ++Q  
Sbjct: 1004 EKRLQQSLLQVTGEKD--NEINQLQQRIDEMQQHIENLCQ-QHEEVLLRAEN---DKQQA 1057

Query: 670  ALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSA 729
             L A   + AL+ E L+    ++     ++E  K +   K +        L D+L ++  
Sbjct: 1058 LLIAHHDQQALM-EKLETVLHEMEEEKNNVERVKREAAVKTEQERNNINQLRDELNRLKT 1116

Query: 730  EKISELLAKINHEEQSKIQTQFGIDAKIQERDLY---IENIESELSKYKSRICRLEESIA 786
             K+ E   K + E   KI+    I+   +ER+L     E ++ +L   + ++  L+  + 
Sbjct: 1117 -KLDETRLKTDEE---KIKLDLKIEELWKERELAQRESEELQVQLHMTEDKVDSLQNQLH 1172

Query: 787  VMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEH 846
                +    E   + L   L + ++   + T ++++  +    L +H + +E +  E   
Sbjct: 1173 ETIRKLKDAENLNETLRKELVDIRRQLGDSTYEKEKYNSSNKELREHVKRIESEKREQNR 1232

Query: 847  ENKELQKKNQILLE-------ENQNLQISLSDMQQHYNALVEKANRT--DLAESESTKYQ 897
              +E  +K   L +       E   LQ  + DM++    L ++ + T  +L +S  +  Q
Sbjct: 1233 ILEESYQKISALEDMKVNVDAERSRLQAQIRDMEKEMLQLQKQLHFTQDELQKSHQSNAQ 1292

Query: 898  TQL--RDLESNLKRITHEHQTL---IVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEK 952
             Q   ++L++ L   T E + L   + Q KK++ D++       +   R +   +E+ E+
Sbjct: 1293 AQNDEKELQARLTNETEERERLQLQLHQVKKQLMDVDNSLKVTRQELGRLRSRADEENER 1352

Query: 953  NIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEIN 1012
                  +L  +L++ +     L     E  K NLE+      +Q  +           + 
Sbjct: 1353 WRVREQELVVRLEDSRCRERKL-----EDQKHNLEVCLADASQQIQELKARLGGSEGRVR 1407

Query: 1013 KLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLL 1072
             L+A L Q +     + QK+++   +   +             KL +     +R S    
Sbjct: 1408 ALDAQLSQLEITKKEVEQKLSSVGSTLRRIAGIQMDGSVNIPFKLLSPS---RRWSPARG 1464

Query: 1073 DSKQHNEELQILVREQDDQI-----KELKE--TKLTFEMNIPKTEGMIISSTIEPMSDDA 1125
             S+ H +  + ++ + D +I     + L +   ++  E +  KTE   +   ++   +  
Sbjct: 1465 TSQDHIDSSRDVILDVDPEIIRKGVRSLMQQVAQIERERDDYKTELCNLKKQLDENQEIQ 1524

Query: 1126 NNVDXXXXXXXXXXXXLKVQE---EEEFIQERSVLQEQSAKLNTELQECYT---KIIQLE 1179
            N  D            L+ ++   E +  Q++S  + Q   L  + +EC     KII LE
Sbjct: 1525 NRSDIQINTLLTNIRMLQDEKNSLEVKLSQKQSGYEMQLNALQLKSEECEQLREKIINLE 1584

Query: 1180 TLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELW 1239
             + +  +   +  +E++++LK  L ++  E  NL   +++  S  +    QR     +L 
Sbjct: 1585 LMISNNSEEKIQFEEKLDKLKQVLNKVENEKRNLQEELSKSESRATKLELQRMSLEGDLQ 1644

Query: 1240 KQ-----------HLAQREADFQ-KTEHELRVQLSAFESKYEQL---LDSVQSSTQEETN 1284
            +            H  Q   D Q +T   L  + ++ +S  EQL   L+   ++  E  N
Sbjct: 1645 RLQMMFQEKDANIHKLQERNDTQNRTMTTLEERCTSLKSMVEQLNLALEKASTTENELKN 1704

Query: 1285 KIVTMEQ-VTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXX 1343
            +I +M+  +  L   LQ   E  + LQ++ ++  N+  IL   IE  + +          
Sbjct: 1705 EINSMQHNIMELTTTLQTSNEKNKQLQKQISNAENERRILSERIESMQQSLN-------- 1756

Query: 1344 XXXXXXXDLRTENQSYK-QMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKV 1402
                   DL+  NQ+   Q+        N E  +    S             +N  E   
Sbjct: 1757 -------DLKHTNQTLTDQITRLQNELANNEVQRCALESQLRIVAYPTQEENINKDE--- 1806

Query: 1403 LELTHQLELKD---SEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESEL 1459
             EL  QL++     SE+  K       +     +  N+ +QL  ++      +YE+  + 
Sbjct: 1807 -ELLRQLQIAQRERSEMRGKMEALNDKMKLLEADKRNLERQLSLFKSTNRSKSYERYEKA 1865

Query: 1460 AILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKT 1519
                L    + +HYE   +E  ++  +L  +L  K  E + L       +   +    +T
Sbjct: 1866 HTELLGTSFDIDHYEQENRELRLKVRRLETQLAEKEAELIRLKSSYTHTHSVFDFNRDRT 1925

Query: 1520 NEMQ 1523
             E++
Sbjct: 1926 GEIE 1929



 Score = 95.5 bits (227), Expect = 1e-17
 Identities = 237/1264 (18%), Positives = 533/1264 (42%), Gaps = 136/1264 (10%)

Query: 147  LSNTIKEKDNALSVLQVKMKIMETTILDLQ-EKI--NEKDQIIEAKNKATTXXXXXXXXX 203
            L+N   ++   L  L+ ++   E T LDL+ EK+  NEK + +E + +            
Sbjct: 763  LANQCTDQQGDLGSLRKELLQAEQTRLDLESEKVTLNEKVKFLEIEKEKIEIELAQVTRE 822

Query: 204  XXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAA 263
                     D   Q++ +      +  E    KQRL +  E       +LE+  K  E  
Sbjct: 823  RG-------DFNNQLSVLARKKETLNEELMRLKQRLEQANEMNGRINRNLEDLVKDNEEK 875

Query: 264  RFEISLEHSKLAQELEQXXXXXXXXXXXXXXL--AKQSIEPSCEEKTEIEEKGSLEIANM 321
            +  +     ++ +  EQ              L   + S+E    +KT++E++    +   
Sbjct: 876  QVLLETNEKEVQRLQEQLASMRSEKETLEGVLFDTQTSLENMHVKKTQLEKEQKELLIKQ 935

Query: 322  TELTKKIELL----EHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRN 377
              L  ++E L    E+   +I +  + L  +      E + + S  KK S    +K    
Sbjct: 936  ESLKGQVERLMKDLENSEKRIHEVKQTLTQQSGDQEAEFQQIISNVKKHSEENIKKLNEE 995

Query: 378  TASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVD-----KEYVISEKD 432
               ++K    +   ++L Q T +K   NEI +L+  I  + + + +     +E ++  ++
Sbjct: 996  K-EQIKINLEKRLQQSLLQVTGEK--DNEINQLQQRIDEMQQHIENLCQQHEEVLLRAEN 1052

Query: 433  TXXXXXXXXXXGKDTLIAQLQ-LEHQQHMEGPSLIHV----GTNTE-DVNEIAKVQEQLK 486
                        +  L+ +L+ + H+   E  ++  V       TE + N I +++++L 
Sbjct: 1053 DKQQALLIAHHDQQALMEKLETVLHEMEEEKNNVERVKREAAVKTEQERNNINQLRDELN 1112

Query: 487  QELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKL---KLKQMQKT 543
            + L  ++ +  +K   EK+K  + +I +L  E + A +   +++    +   K+  +Q  
Sbjct: 1113 R-LKTKLDETRLKTDEEKIK-LDLKIEELWKERELAQRESEELQVQLHMTEDKVDSLQNQ 1170

Query: 544  I-DNFSKVSDSNKEIVRLTEELHHLSQKVAE--LEEEKGN-----LQLHLVDYDSGRMIE 595
            + +   K+ D+      L +EL  + +++ +   E+EK N     L+ H+   +S +  +
Sbjct: 1171 LHETIRKLKDAENLNETLRKELVDIRRQLGDSTYEKEKYNSSNKELREHVKRIESEKREQ 1230

Query: 596  SDV----YKKMIEMENL-----AE-TRLKA-ISLLESQKFDLVQELHILQQKYDEVEDKL 644
            + +    Y+K+  +E++     AE +RL+A I  +E +   L ++LH  Q   DE++   
Sbjct: 1231 NRILEESYQKISALEDMKVNVDAERSRLQAQIRDMEKEMLQLQKQLHFTQ---DELQKSH 1287

Query: 645  ADISQLQSDQVCSEIKSVHLEEQIDALSAS----KKELALVIENLKLDKEQLYGTIK--- 697
               +Q Q+D+   + +  +  E+ + L       KK+L  V  +LK+ +++L G ++   
Sbjct: 1288 QSNAQAQNDEKELQARLTNETEERERLQLQLHQVKKQLMDVDNSLKVTRQEL-GRLRSRA 1346

Query: 698  DLENDK-----EDIMNKLQNYIQENMDLTDKLEKM------SAEKISELLAKINHEEQSK 746
            D EN++     ++++ +L++       L D+   +      ++++I EL A++   E  +
Sbjct: 1347 DEENERWRVREQELVVRLEDSRCRERKLEDQKHNLEVCLADASQQIQELKARLGGSE-GR 1405

Query: 747  IQTQFGIDAKIQERDLYIENIESELSKYKSRICRLE----ESIAVMEDRRYSLERKADQL 802
            ++    +DA++ + ++  + +E +LS   S + R+     +    +  +  S  R+    
Sbjct: 1406 VRA---LDAQLSQLEITKKEVEQKLSSVGSTLRRIAGIQMDGSVNIPFKLLSPSRRWSPA 1462

Query: 803  GSYLQEKQKAYSEYTIQEDELVNRLAV--LMDHDRVVEKQLLEIEHENKELQKKNQILLE 860
                Q+   +  +  +  D  + R  V  LM     +E++  + + E   L+K+    L+
Sbjct: 1463 RGTSQDHIDSSRDVILDVDPEIIRKGVRSLMQQVAQIERERDDYKTELCNLKKQ----LD 1518

Query: 861  ENQNLQ----ISLSDMQQHYNALVEKANRTDLAESESTK-YQTQLRDLESNLKRITHEHQ 915
            ENQ +Q    I ++ +  +   L ++ N  ++  S+    Y+ QL  L+   +      +
Sbjct: 1519 ENQEIQNRSDIQINTLLTNIRMLQDEKNSLEVKLSQKQSGYEMQLNALQLKSEECEQLRE 1578

Query: 916  TLI---------VQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQE 966
             +I          ++K + E+   +    +     +K+ L E+  K+    T+LE Q   
Sbjct: 1579 KIINLELMISNNSEEKIQFEEKLDKLKQVLNKVENEKRNLQEELSKSESRATKLELQRMS 1638

Query: 967  YKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEII 1026
             + +++ L M  +E         D ++ K Q ++ D   + +  + +    LK   E++ 
Sbjct: 1639 LEGDLQRLQMMFQEK--------DANIHKLQERN-DTQNRTMTTLEERCTSLKSMVEQLN 1689

Query: 1027 ALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVR 1086
               +K +  +    + ++  +  + + TT L+   E+ +++ KQ+ +++     L   + 
Sbjct: 1690 LALEKASTTENELKNEINSMQHNIMELTTTLQTSNEKNKQLQKQISNAENERRILSERIE 1749

Query: 1087 EQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQE 1146
                 + +LK T  T    I + +  + ++ ++  +     ++              + +
Sbjct: 1750 SMQQSLNDLKHTNQTLTDQITRLQNELANNEVQRCA-----LESQLRIVAYPTQEENINK 1804

Query: 1147 EEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQL 1206
            +EE +++  + Q + +++  +++    K+  LE     L    +   +  N+ KS  E+ 
Sbjct: 1805 DEELLRQLQIAQRERSEMRGKMEALNDKMKLLEADKRNLE-RQLSLFKSTNRSKS-YERY 1862

Query: 1207 NTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFES 1266
               +  LL T        S  +D    E  EL    L  R  + Q  E E   +L   +S
Sbjct: 1863 EKAHTELLGT--------SFDIDHYEQENREL---RLKVRRLETQLAEKE--AELIRLKS 1909

Query: 1267 KYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSE 1326
             Y     SV    ++ T +I  +        KL +  E  ++ +++   + NQI++LR +
Sbjct: 1910 SYTH-THSVFDFNRDRTGEIERLRAAQLQAEKLLEARE--QSHRQQVLRLENQIQLLREQ 1966

Query: 1327 IEDE 1330
            +  E
Sbjct: 1967 LNQE 1970



 Score = 86.2 bits (204), Expect = 7e-15
 Identities = 196/1086 (18%), Positives = 454/1086 (41%), Gaps = 77/1086 (7%)

Query: 58   QKCLENAALVSKRIKEHRKATAELLGRPFVPGISESLANTLKQKEILMEKIKQYKELSKR 117
            Q  LEN  +   ++++ +K    L+ +  + G  E L   L+  E  + ++KQ       
Sbjct: 911  QTSLENMHVKKTQLEKEQKEL--LIKQESLKGQVERLMKDLENSEKRIHEVKQTLTQQSG 968

Query: 118  SSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQE 177
                  +               +L +         EK    S+LQV  +  +  I  LQ+
Sbjct: 969  DQEAEFQQIISNVKKHSEENIKKLNEEKEQIKINLEKRLQQSLLQVTGE-KDNEINQLQQ 1027

Query: 178  KINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQ 237
            +I+E  Q IE   +                       +Q + +  E  +    E K+  +
Sbjct: 1028 RIDEMQQHIENLCQQHEEVLLRAENDKQQALLIAHHDQQALMEKLETVLHEMEEEKNNVE 1087

Query: 238  RLLKDIESKDVRISSLEEANKLL-EAARFEISLEHSKLAQELEQXXXXXXXXXX-XXXXL 295
            R+ ++   K  +       N+L  E  R +  L+ ++L  + E+               L
Sbjct: 1088 RVKREAAVKTEQ--ERNNINQLRDELNRLKTKLDETRLKTDEEKIKLDLKIEELWKEREL 1145

Query: 296  AKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTE 355
            A++  E    +    E+K       + E  +K++  E+LN  +R+   ++  +L     E
Sbjct: 1146 AQRESEELQVQLHMTEDKVDSLQNQLHETIRKLKDAENLNETLRKELVDIRRQLGDSTYE 1205

Query: 356  SKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKN-EIAKLEMVI 414
             +  +S +K+    + R        + ++   + S + ++   D K+N + E ++L+  I
Sbjct: 1206 KEKYNSSNKELREHVKRIESEK---REQNRILEESYQKISALEDMKVNVDAERSRLQAQI 1262

Query: 415  QSLNKDLVDKE----YVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIH-VG 469
            + + K+++  +    +   E              +  L A+L  E ++       +H V 
Sbjct: 1263 RDMEKEMLQLQKQLHFTQDELQKSHQSNAQAQNDEKELQARLTNETEERERLQLQLHQVK 1322

Query: 470  TNTEDVNEIAKVQEQ----LKQELNDEIKDVNVKD--LIEKLKSAEEQITQLNDE----- 518
                DV+   KV  Q    L+   ++E +   V++  L+ +L+ +  +  +L D+     
Sbjct: 1323 KQLMDVDNSLKVTRQELGRLRSRADEENERWRVREQELVVRLEDSRCRERKLEDQKHNLE 1382

Query: 519  --IDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEE 576
              +  A++ + ++K+       +++      S++  + KE+ +    +    +++A ++ 
Sbjct: 1383 VCLADASQQIQELKARLGGSEGRVRALDAQLSQLEITKKEVEQKLSSVGSTLRRIAGIQM 1442

Query: 577  EKG-NLQLHLVD---------------YDSGRMIESDVYKKMIEMENLAETRLKAISLLE 620
            +   N+   L+                 DS R +  DV  ++I       + ++ ++ +E
Sbjct: 1443 DGSVNIPFKLLSPSRRWSPARGTSQDHIDSSRDVILDVDPEIIRKG--VRSLMQQVAQIE 1500

Query: 621  SQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELA- 679
             ++ D   EL  L+++ DE ++ + + S +Q + + + I+ +  E+    +  S+K+   
Sbjct: 1501 RERDDYKTELCNLKKQLDENQE-IQNRSDIQINTLLTNIRMLQDEKNSLEVKLSQKQSGY 1559

Query: 680  -LVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQ--ENMD-LTDKLEKMSAEK--IS 733
             + +  L+L  E+     + + N +  I N  +  IQ  E +D L   L K+  EK  + 
Sbjct: 1560 EMQLNALQLKSEECEQLREKIINLELMISNNSEEKIQFEEKLDKLKQVLNKVENEKRNLQ 1619

Query: 734  ELLAKINHEEQSKIQTQ-FGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRR 792
            E L+K +    +K++ Q   ++  +Q   +  +  ++ + K + R      ++  +E+R 
Sbjct: 1620 EELSK-SESRATKLELQRMSLEGDLQRLQMMFQEKDANIHKLQERNDTQNRTMTTLEERC 1678

Query: 793  YSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQ 852
             SL+   +QL   L++     +E   + + + + +  L    +   ++  +++ +    +
Sbjct: 1679 TSLKSMVEQLNLALEKASTTENELKNEINSMQHNIMELTTTLQTSNEKNKQLQKQISNAE 1738

Query: 853  KKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITH 912
             + +IL E  +++Q SL+D++     L ++  R    ++E    + Q   LES L+ + +
Sbjct: 1739 NERRILSERIESMQQSLNDLKHTNQTLTDQITR---LQNELANNEVQRCALESQLRIVAY 1795

Query: 913  EHQTLIVQKKKEIEDLEIEFNTQIESAIRDK-KVLNEKYEKNIEYVTQLEAQLQEYKNNI 971
              Q   + K +E+   +++   +  S +R K + LN+K +        LE QL  +K+  
Sbjct: 1796 PTQEENINKDEELL-RQLQIAQRERSEMRGKMEALNDKMKLLEADKRNLERQLSLFKST- 1853

Query: 972  ENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQK 1031
             N + + E   K + EL+         +  +   +   ++ +L   L +K+ E+I L   
Sbjct: 1854 -NRSKSYERYEKAHTELLGTSFDIDHYEQEN--RELRLKVRRLETQLAEKEAELIRL--- 1907

Query: 1032 INNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQ 1091
               +  ++   V D+       T ++E +    Q  +++LL++++ +   Q+L    ++Q
Sbjct: 1908 --KSSYTHTHSVFDFN---RDRTGEIERL-RAAQLQAEKLLEAREQSHRQQVL--RLENQ 1959

Query: 1092 IKELKE 1097
            I+ L+E
Sbjct: 1960 IQLLRE 1965


>UniRef50_UPI0000ECA83C Cluster: Centrosome-associated protein CEP250
            (Centrosomal protein 2) (Centrosomal Nek2-associated
            protein 1) (C-Nap1).; n=2; Gallus gallus|Rep:
            Centrosome-associated protein CEP250 (Centrosomal protein
            2) (Centrosomal Nek2-associated protein 1) (C-Nap1). -
            Gallus gallus
          Length = 2424

 Score =  123 bits (297), Expect = 4e-26
 Identities = 230/1151 (19%), Positives = 485/1151 (42%), Gaps = 88/1151 (7%)

Query: 220  KMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELE 279
            KM EN    E E   E++ +L  ++ +D     +EE    L A+         K  QEL 
Sbjct: 944  KMVENMHKEEMENIKEEKNIL--LQQRDDLQKQVEELTSQLAASEESHQAIGHKAQQELS 1001

Query: 280  QXXXXXXXXXXXXXXLAKQSIEPSCEEKT----EIEEKGSLEIANMTELTKKIELLEHLN 335
            +                ++ +  S E+K      +EE   ++   +++L   I+  + L+
Sbjct: 1002 EAQELSRQKALESE---RERLSLSLEQKELSLKTLEENNLVQQNEVSKLHSAIQQAQQLH 1058

Query: 336  CQIRQTNKELENKLATMGTE--SKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSET 393
               R+  +EL N++ T+      K  S  +++   L   +  R     ++     L +E 
Sbjct: 1059 SDHRREIQELNNQVQTLQEVVLEKEASLAAREKQLLQDLEESRAGERCLRDSLHVLEAEM 1118

Query: 394  LNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQ 453
                      +N    L    Q  N    + +  + +              K   +    
Sbjct: 1119 AELHLRLCSTENRAKALATECQQANNAHCEAQSQLDKLHLVLHHVLCDSTDKSRDLVAWS 1178

Query: 454  LEHQQHMEGPSLIHV-GTNTE-DVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQ 511
             E Q H+ G ++      + E  V+ +A   + L+Q+L    +D+N  D  +K++  E +
Sbjct: 1179 SE-QDHVWGLTVSQAKDLHVELTVDRVAAALQDLRQDLKQTQQDLN--DAGKKVQDLELE 1235

Query: 512  ITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNF-SKVSDSNKEIVRLTEELHHLSQK 570
            +++   E D  + +  +++     +L Q Q+    + ++ +   KE + L +E+  L +K
Sbjct: 1236 LSKRQAERDHFSAHNQELQK----QLAQSQEVFSGWKAEAAALKKEAITLHQEVASLERK 1291

Query: 571  VAELEEEKGNLQLHLVDYDSGRMIESDVY---KKMIEMENLAETRLK-AISLLESQKFDL 626
            +   E++K ++ LH  + D  + +E  +    K + E    +ETR   A  +  S + +L
Sbjct: 1292 LESAEKQKKDV-LH--ERDRLQAVEEKLMWEIKILQESVTASETRANTAADMNHSLEQEL 1348

Query: 627  VQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELAL------ 680
               L +L+ K  EV+ +   I  LQ +    +    +L +    LS  + E+ L      
Sbjct: 1349 QTTLSVLKTKNKEVDAQWEKIQMLQKEAADVKALQENLIQVNAILSKREGEMKLYQEQMR 1408

Query: 681  VIENLK-LDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKI 739
            ++EN K + K  L   IKD++  KE   ++ Q  IQE ++   +L++    K+S+ L   
Sbjct: 1409 MLENQKEMHKTTLDQVIKDIKEKKEKTESQ-QEQIQE-LEKQQELQRTVISKMSKDLEDR 1466

Query: 740  NHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKA 799
            + E +S+ +  + ++ + + +   +  +  +L+     I   +E I  +E  R  L+R A
Sbjct: 1467 DKEIRSQQEEIWELEKQQELQRTVVSKMTKDLAHRDQEIQSQQEEIQELEKER-ELQRTA 1525

Query: 800  DQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRV-VEKQLLEIEHENKELQKKNQIL 858
                S + +  K   E    + EL+  L    +  R  + K    +E  ++E++ + +++
Sbjct: 1526 ---ASKMSKDLKERDEKIRSQQELIEELEKQQELQRTALSKMSKNLEERDQEIKSQQELI 1582

Query: 859  LEENQNLQISLSDMQQHYNALVEKAN--RTDLAESESTKYQTQL-RDLESNLKRITHEHQ 915
             E  +  ++  + + +    L E+    R+   E +  + Q +L R + S + +   E  
Sbjct: 1583 EELKKQQELQRTAVSKMNKDLEERDQEIRSQQEEIQELEKQRELQRTILSKMSKDLEEKD 1642

Query: 916  TLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKY-EKNIEYVT--QLEAQLQEYKNNIE 972
             +I  ++ ++  LE    +Q+ S + D   +     EKN+E ++  Q   +L+  +  ++
Sbjct: 1643 QVIKFQEGKVMILEQHGTSQVRSLLVDLDHMKGNLKEKNLELMSLNQQIKELEMEREEVK 1702

Query: 973  NLNMNVEELNKMNLELIDKH-VQKQQT----QSPDYTEQYINE----INKLNALLKQKDE 1023
            +L+ ++E+L  +  +  ++   Q+ Q     Q  ++ E+Y+ E    + K+   L +KD+
Sbjct: 1703 SLHTSLEQLRAVLRDRENESDSQRDQLRLFQQYKEHQEEYLQELQDKVEKMTLSLSKKDQ 1762

Query: 1024 EIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQI 1083
            E+ +  ++I  A+      +     +L Q    L+  E  +    +Q  + ++  E++ +
Sbjct: 1763 ELESQQKQIQEAEEVMEKKLKTVCDQLEQTLETLKEKERLLDIQKQQTREYEEKTEQMNV 1822

Query: 1084 LVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLK 1143
            L R+ +     L+E  L  E      E      T +   DD+                LK
Sbjct: 1823 LCRDLEYTKAILREKDLMIESQKELIE------TFQKQEDDSMQ---QKEILQHLKGALK 1873

Query: 1144 VQEEEEFIQERS--VLQEQSAKLNTELQECYTKIIQ-LETLNTELTGHDVVNQEQINQLK 1200
             QE+E     +     +E+  K  T+     T I+Q L+   + L   D    ++I  LK
Sbjct: 1874 EQEQETLSLRKQCEAFKEKEEKHKTDQT---TAIVQKLQCAESSLAARD----QEIASLK 1926

Query: 1201 SKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQ 1260
              +++L  + ++    V  L+  ++           ++ KQ  +++   F   E   +V 
Sbjct: 1927 EHVQELQKQKESEAKQVKSLQQDLNKMSKTMKKNNLQILKQ--SEQINVFHICEESRKVA 1984

Query: 1261 LSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQI 1320
            L + +++   L + V+   ++E N+        +L  KLQ +EE L+ LQ     +  + 
Sbjct: 1985 LLSCQNQVSLLEEVVRK--RDEDNE--------TLLQKLQHQEEELKTLQNLQLMLSEKK 2034

Query: 1321 EILRSEIEDEK 1331
            E ++   E+EK
Sbjct: 2035 EEIKRHGEEEK 2045



 Score =  120 bits (290), Expect = 3e-25
 Identities = 224/1154 (19%), Positives = 480/1154 (41%), Gaps = 74/1154 (6%)

Query: 456  HQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQL 515
            HQQH++  SL+ +     D   + K++ +L+Q+L  E+ +     L +     + +    
Sbjct: 409  HQQHLK--SLV-LALKC-DCENLEKIRGELQQKL--ELSEQEASRLRQSNTELQLKEDSA 462

Query: 516  NDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELE 575
              E       M +   +H+L LK +    +  S + +   E+V   E+L     +   L+
Sbjct: 463  QGEKVEQQLAMERAHHDHELVLKDLAALEEKHSLLQN---ELVAAREKLEESHLQRDLLK 519

Query: 576  EEKGNLQLHLVDYDSGRMIESDVYKKM-IEMENLAETRLKAISLLESQKFDLVQELHILQ 634
            +EK  L + L   +      +    K+  E+ +L     K  S+ E+   D V EL+ L 
Sbjct: 520  QEKHELTVALEKAEKSVAALTGAQNKLNSEIADLHTAAAKMSSINEALALDKV-ELNKLV 578

Query: 635  QKYDEVEDKLAD-ISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLY 693
             + ++  + L+D +++++  +V  + K    +   + L A K  L  +++  +  +E+L 
Sbjct: 579  LQLEQENELLSDKVNEMERAKVSEQEKITLYKRTNEELCAEKSHLEKLLKKAEEQQEELQ 638

Query: 694  GTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKM--SAEKISELLAKINHEEQSKIQTQF 751
              ++ L  +KE+ + KL    ++    +  LE++   + +  + +AK++ E++  +  + 
Sbjct: 639  MQLRILAEEKEETLEKLNQVYRQQESASSGLEQLRQQSSRQEDAVAKVSKEKEFLVHEKA 698

Query: 752  GIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQK 811
             ++ ++   +   + +  +L++ +S    LE S+   + +   LE    QL   L     
Sbjct: 699  ALEVRLAAVERDRQGLSEQLAEARSVKDTLESSLFEAQQQLSHLEITKSQLEIQLHT--- 755

Query: 812  AYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSD 871
                  +Q  E++      + ++   E+ L++ E +N   Q+  QI  + N  L++  +D
Sbjct: 756  -----VVQAKEVIQGEVKCLQYELETERCLMKQEQKNM-AQRLIQIEEQHNNTLKLQQTD 809

Query: 872  MQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEI- 930
             +   N L++  +     E    + Q +L   E        +H+  +   K+++  ++  
Sbjct: 810  HEVEINKLLQ--DLASEREGRQLELQERLELWEKEKAEAEGQHEKKLFHMKEKVATMQAQ 867

Query: 931  --EFNTQIESAIRDKKVLNEKYEKN---IEYVTQLEAQLQEYKNNIENLNMNVEELNKMN 985
              E  T++ESA  ++++L EK  +    +E + Q + +L E  + +E L   V+E  +  
Sbjct: 868  QEEERTRVESA--NQEILTEKENEKKALLETLLQTQGELTEACHQLEQLRQEVKEQQEYE 925

Query: 986  LELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKIN-NAQVSYM-SMV 1043
              + +K   + + Q      + +  ++K   +   K+E+ I L Q+ +   QV  + S +
Sbjct: 926  QNITEK--LQAELQETHCKIKMVENMHK-EEMENIKEEKNILLQQRDDLQKQVEELTSQL 982

Query: 1044 SDYESKLAQFTTKLENMEEEMQRVSKQ-LLDSKQHNEELQILVREQDDQIKELKETKLTF 1102
            +  E        K +    E Q +S+Q  L+S++  E L + + +++  +K L+E  L  
Sbjct: 983  AASEESHQAIGHKAQQELSEAQELSRQKALESER--ERLSLSLEQKELSLKTLEENNLVQ 1040

Query: 1103 EMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSA 1162
            +  + K     I    +  SD    +             +  +E     +E+ +LQ+   
Sbjct: 1041 QNEVSKLHS-AIQQAQQLHSDHRREIQELNNQVQTLQEVVLEKEASLAAREKQLLQDLEE 1099

Query: 1163 KLNTELQECYTKIIQ-LETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELR 1221
                E   C    +  LE    EL       + +   L ++ +Q N  +    S + +L 
Sbjct: 1100 SRAGE--RCLRDSLHVLEAEMAELHLRLCSTENRAKALATECQQANNAHCEAQSQLDKLH 1157

Query: 1222 SSISSAVDQRGFEIAEL--W---KQHLAQREADFQKTEH-ELRV-QLSAFESKYEQLLDS 1274
              +   +     +  +L  W   + H+        K  H EL V +++A      Q L  
Sbjct: 1158 LVLHHVLCDSTDKSRDLVAWSSEQDHVWGLTVSQAKDLHVELTVDRVAAALQDLRQDLKQ 1217

Query: 1275 VQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAF 1334
             Q    +   K+  +E   S   K Q + +H     ++    + Q + + S  + E  A 
Sbjct: 1218 TQQDLNDAGKKVQDLELELS---KRQAERDHFSAHNQELQKQLAQSQEVFSGWKAEAAAL 1274

Query: 1335 XXXXXXXXXXXXXXXXDLRT-ENQSYKQMQEQSILNINEE----NAQLKKSSXXXXXXXX 1389
                             L + E Q    + E+  L   EE      ++ + S        
Sbjct: 1275 KKEAITLHQEVASLERKLESAEKQKKDVLHERDRLQAVEEKLMWEIKILQESVTASETRA 1334

Query: 1390 XXXXRVNDAEAKVLELT-HQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRI 1448
                 +N +  + L+ T   L+ K+ E+  +  +  + L +   + + +++ L++    +
Sbjct: 1335 NTAADMNHSLEQELQTTLSVLKTKNKEVDAQWEKIQM-LQKEAADVKALQENLIQ----V 1389

Query: 1449 EDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAEL 1508
              +  ++E E+ + + +M    N  E M K +  + +K I+E   K TE  S  +Q+ EL
Sbjct: 1390 NAILSKREGEMKLYQEQMRMLENQKE-MHKTTLDQVIKDIKEKKEK-TE--SQQEQIQEL 1445

Query: 1509 NKALEEEVAKTNEMQTALENQEIEIVTLNDEITNL---QNMVRASSSKIQKHVSFASDTK 1565
             K  E +    ++M   LE+++ EI +  +EI  L   Q + R   SK+ K ++      
Sbjct: 1446 EKQQELQRTVISKMSKDLEDRDKEIRSQQEEIWELEKQQELQRTVVSKMTKDLAHRDQEI 1505

Query: 1566 QGRDEQLDNTMNKE 1579
            Q + E++   + KE
Sbjct: 1506 QSQQEEIQE-LEKE 1518



 Score =  119 bits (287), Expect = 6e-25
 Identities = 289/1571 (18%), Positives = 637/1571 (40%), Gaps = 116/1571 (7%)

Query: 49   ERQIKFERAQKCLENAALVSKRIKEHRKATAELLGRPFVPGISESLANTLKQKEILMEKI 108
            E  +  E+A+K +  AAL   + K + +          +  I+E+LA    +   L+ ++
Sbjct: 524  ELTVALEKAEKSV--AALTGAQNKLNSEIADLHTAAAKMSSINEALALDKVELNKLVLQL 581

Query: 109  KQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQ---LGDVTHLSNTIKEKDNALSVLQVKM 165
            +Q  EL       + R                     + +HL   +K+ +     LQ+++
Sbjct: 582  EQENELLSDKVNEMERAKVSEQEKITLYKRTNEELCAEKSHLEKLLKKAEEQQEELQMQL 641

Query: 166  KIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENF 225
            +I+     +  EK+N   Q+   +  A++                 ED   +++K +E  
Sbjct: 642  RILAEEKEETLEKLN---QVYRQQESASS-----GLEQLRQQSSRQEDAVAKVSKEKEFL 693

Query: 226  IAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXX 285
            +  +A  +     + +D +    +++        LE++ FE   + S L  E+ +     
Sbjct: 694  VHEKAALEVRLAAVERDRQGLSEQLAEARSVKDTLESSLFEAQQQLSHL--EITKSQLEI 751

Query: 286  XXXXXXXXXLAKQSIEPSCEEKTEIEEKGSL---EIANMTELTKKIELLEHLNCQIRQTN 342
                        Q  E  C +  E+E +  L   E  NM +   +IE   +   +++QT+
Sbjct: 752  QLHTVVQAKEVIQG-EVKCLQ-YELETERCLMKQEQKNMAQRLIQIEEQHNNTLKLQQTD 809

Query: 343  KELE-NK-LATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSS-ETLNQDTD 399
             E+E NK L  + +E +      ++   L  ++         K  +       T+    +
Sbjct: 810  HEVEINKLLQDLASEREGRQLELQERLELWEKEKAEAEGQHEKKLFHMKEKVATMQAQQE 869

Query: 400  KKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQH 459
            ++  + E A  E++ +  N+     E ++  +             +  +  + Q E++Q+
Sbjct: 870  EERTRVESANQEILTEKENEKKALLETLLQTQGELTEACHQLEQLRQEV--KEQQEYEQN 927

Query: 460  MEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEI 519
            +       +    E   +I  V+   K+E+ +  ++ N+  L+++    ++Q+ +L  ++
Sbjct: 928  ITEKLQAEL---QETHCKIKMVENMHKEEMENIKEEKNI--LLQQRDDLQKQVEELTSQL 982

Query: 520  DAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAE---LEE 576
             A+ ++   +    + +L + Q+   +  K  +S +E + L+ E   LS K  E   L +
Sbjct: 983  AASEESHQAIGHKAQQELSEAQEL--SRQKALESERERLSLSLEQKELSLKTLEENNLVQ 1040

Query: 577  EKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQK 636
            +    +LH       + + SD  +++ E+ N  +T  + +  LE +     +E  +LQ  
Sbjct: 1041 QNEVSKLHSA-IQQAQQLHSDHRREIQELNNQVQTLQEVV--LEKEASLAAREKQLLQ-- 1095

Query: 637  YDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTI 696
              ++E+  A    L+      E +   L  ++ +     K LA        + +Q     
Sbjct: 1096 --DLEESRAGERCLRDSLHVLEAEMAELHLRLCSTENRAKALA-------TECQQANNAH 1146

Query: 697  KDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQ-TQFGIDA 755
             + ++  + +   L + + ++ D +  L   S+E+       ++  +   ++ T   + A
Sbjct: 1147 CEAQSQLDKLHLVLHHVLCDSTDKSRDLVAWSSEQDHVWGLTVSQAKDLHVELTVDRVAA 1206

Query: 756  KIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSE 815
             +Q+    ++  + +L+    ++  LE  ++  +  R        +L   L + Q+ +S 
Sbjct: 1207 ALQDLRQDLKQTQQDLNDAGKKVQDLELELSKRQAERDHFSAHNQELQKQLAQSQEVFSG 1266

Query: 816  YTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQH 875
            +  +   L      L      +E++L   E + K++  +   L    + L   +  +Q+ 
Sbjct: 1267 WKAEAAALKKEAITLHQEVASLERKLESAEKQKKDVLHERDRLQAVEEKLMWEIKILQES 1326

Query: 876  YNALVEKAN-RTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNT 934
              A   +AN   D+  S   + QT L  L++  K +  + + + + +K+  +   ++ N 
Sbjct: 1327 VTASETRANTAADMNHSLEQELQTTLSVLKTKNKEVDAQWEKIQMLQKEAADVKALQENL 1386

Query: 935  QIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQ 994
               +AI  K+    K  +  E +  LE Q + +K  ++ +  +++E  K   E   + +Q
Sbjct: 1387 IQVNAILSKREGEMKLYQ--EQMRMLENQKEMHKTTLDQVIKDIKE-KKEKTESQQEQIQ 1443

Query: 995  KQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKI---NNAQVSYMSMVSDYESKLA 1051
            + + Q     E     I+K++  L+ +D+EI +  ++I      Q    ++VS     LA
Sbjct: 1444 ELEKQQ----ELQRTVISKMSKDLEDRDKEIRSQQEEIWELEKQQELQRTVVSKMTKDLA 1499

Query: 1052 QFTTKLENMEEEMQRV-----------SKQLLDSKQHNEEL---QILVREQDDQIKELKE 1097
                ++++ +EE+Q +           SK   D K+ +E++   Q L+ E + Q +EL+ 
Sbjct: 1500 HRDQEIQSQQEEIQELEKERELQRTAASKMSKDLKERDEKIRSQQELIEELEKQ-QELQR 1558

Query: 1098 TKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSV- 1156
            T L+      +     I S  E + +     +            L+ +++E   Q+  + 
Sbjct: 1559 TALSKMSKNLEERDQEIKSQQELIEELKKQQELQRTAVSKMNKDLEERDQEIRSQQEEIQ 1618

Query: 1157 -LQEQSAKLNTELQECYTKIIQLETLNTELTGH-DVVNQEQINQLKSKLEQLNTENDNLL 1214
             L++Q     T L +    + + + +     G   ++ Q   +Q++S L  L+    NL 
Sbjct: 1619 ELEKQRELQRTILSKMSKDLEEKDQVIKFQEGKVMILEQHGTSQVRSLLVDLDHMKGNLK 1678

Query: 1215 STVAELRSSISSAVDQRGFEIAELWKQH--LAQREADFQKTEHE---LRVQLSAFE---S 1266
                EL  S++  + +   E  E+   H  L Q  A  +  E+E    R QL  F+    
Sbjct: 1679 EKNLEL-MSLNQQIKELEMEREEVKSLHTSLEQLRAVLRDRENESDSQRDQLRLFQQYKE 1737

Query: 1267 KYEQLLDSVQSSTQEETNKIVTMEQ-VTSLQNKLQDKEEHLRNLQEKYADVINQIE-ILR 1324
              E+ L  +Q   ++ T  +   +Q + S Q ++Q+ EE    +++K   V +Q+E  L 
Sbjct: 1738 HQEEYLQELQDKVEKMTLSLSKKDQELESQQKQIQEAEE---VMEKKLKTVCDQLEQTLE 1794

Query: 1325 SEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSY-------KQMQEQSILNINEENAQL 1377
            +  E E++                  ++   +  Y       K +  +S   + E   + 
Sbjct: 1795 TLKEKERLLDIQKQQTREYEEKTEQMNVLCRDLEYTKAILREKDLMIESQKELIETFQKQ 1854

Query: 1378 KKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLE-LKDSEIYQKTHEYTITLTQRNDEFEN 1436
            +  S             + + E + L L  Q E  K+ E   KT + T  + +      +
Sbjct: 1855 EDDSMQQKEILQHLKGALKEQEQETLSLRKQCEAFKEKEEKHKTDQTTAIVQKLQCAESS 1914

Query: 1437 VR---QQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNV 1493
            +    Q++   ++ +++L  +KESE   ++  + ++ N      K++ ++ +K  E++NV
Sbjct: 1915 LAARDQEIASLKEHVQELQKQKESEAKQVK-SLQQDLNKMSKTMKKNNLQILKQSEQINV 1973

Query: 1494 -KITES------VSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNM 1546
              I E       +S   QV+ L + + +       +   L++QE E+ TL     NLQ M
Sbjct: 1974 FHICEESRKVALLSCQNQVSLLEEVVRKRDEDNETLLQKLQHQEEELKTLQ----NLQLM 2029

Query: 1547 VRASSSKIQKH 1557
            +     +I++H
Sbjct: 2030 LSEKKEEIKRH 2040



 Score =  110 bits (265), Expect = 3e-22
 Identities = 277/1423 (19%), Positives = 584/1423 (41%), Gaps = 119/1423 (8%)

Query: 215  KQQMTKMQENFIAMEAEWKDEKQRLL---------KDIESKDVRISSLEEANKLLEAA-R 264
            ++++  M+E    M+A+ ++E+ R+          K+ E K +  + L+   +L EA  +
Sbjct: 851  EKKLFHMKEKVATMQAQQEEERTRVESANQEILTEKENEKKALLETLLQTQGELTEACHQ 910

Query: 265  FEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTE-IEEKGSLEIANMTE 323
             E   +  K  QE EQ                 + +E   +E+ E I+E+ ++ +    +
Sbjct: 911  LEQLRQEVKEQQEYEQNITEKLQAELQETHCKIKMVENMHKEEMENIKEEKNILLQQRDD 970

Query: 324  LTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMK 383
            L K++E L        ++++ + +K     +E++ +S    +   L S +   + + + K
Sbjct: 971  LQKQVEELTSQLAASEESHQAIGHKAQQELSEAQELS----RQKALESERERLSLSLEQK 1026

Query: 384  SPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXX 443
                +LS +TL ++    + +NE++KL   IQ   +   D    I E +           
Sbjct: 1027 ----ELSLKTLEENN--LVQQNEVSKLHSAIQQAQQLHSDHRREIQELNNQVQTLQEVVL 1080

Query: 444  GKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIE 503
             K+   A L    +Q ++            D+ E    +  L+  L+  + +  + +L  
Sbjct: 1081 EKE---ASLAAREKQLLQ------------DLEESRAGERCLRDSLH--VLEAEMAELHL 1123

Query: 504  KLKSAEEQITQLNDEIDAANKNMIKVKSN-HKLKLKQMQKTIDNFSKVSDSNKEIVRLTE 562
            +L S E +   L  E   AN    + +S   KL L       D+    +D ++++V  + 
Sbjct: 1124 RLCSTENRAKALATECQQANNAHCEAQSQLDKLHLVLHHVLCDS----TDKSRDLVAWSS 1179

Query: 563  ELHHL-SQKVAELEEEKGNLQLHLV---------DYDSGRMIESDVYKKMIEMENLAETR 612
            E  H+    V++ ++    L +  V         D    +   +D  KK+ ++E     R
Sbjct: 1180 EQDHVWGLTVSQAKDLHVELTVDRVAAALQDLRQDLKQTQQDLNDAGKKVQDLELELSKR 1239

Query: 613  LKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALS 672
                    +   +L ++L   Q+ +   +   A+ + L+ + +    +   LE ++++  
Sbjct: 1240 QAERDHFSAHNQELQKQLAQSQEVFSGWK---AEAAALKKEAITLHQEVASLERKLESAE 1296

Query: 673  ASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEK-MSAEK 731
              KK++    + L+  +E+L   IK L+        +       N  L  +L+  +S  K
Sbjct: 1297 KQKKDVLHERDRLQAVEEKLMWEIKILQESVTASETRANTAADMNHSLEQELQTTLSVLK 1356

Query: 732  ISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDR 791
                      E+   +Q +   D K  + +L    + + LSK +  +   +E + ++E++
Sbjct: 1357 TKNKEVDAQWEKIQMLQKE-AADVKALQENLI--QVNAILSKREGEMKLYQEQMRMLENQ 1413

Query: 792  RYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDR-VVEKQLLEIEHENKE 850
            +   +   DQ+   ++EK+    E T  + E +  L    +  R V+ K   ++E  +KE
Sbjct: 1414 KEMHKTTLDQVIKDIKEKK----EKTESQQEQIQELEKQQELQRTVISKMSKDLEDRDKE 1469

Query: 851  LQKKNQIL--LEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQL-RDLESNL 907
            ++ + + +  LE+ Q LQ ++        A  ++  ++   E +  + + +L R   S +
Sbjct: 1470 IRSQQEEIWELEKQQELQRTVVSKMTKDLAHRDQEIQSQQEEIQELEKERELQRTAASKM 1529

Query: 908  KRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEY 967
             +   E    I  +++ IE+LE +   Q  +  +  K L E+ +   E  +Q E  ++E 
Sbjct: 1530 SKDLKERDEKIRSQQELIEELEKQQELQRTALSKMSKNLEERDQ---EIKSQQEL-IEEL 1585

Query: 968  KNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIA 1027
            K   E     V ++NK +LE  D+ ++ QQ +  +  +Q   E+ +   +L +  +++  
Sbjct: 1586 KKQQELQRTAVSKMNK-DLEERDQEIRSQQEEIQELEKQ--RELQR--TILSKMSKDLEE 1640

Query: 1028 LNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVRE 1087
             +Q I   +   M +     S++      L++M+  ++  + +L+   Q  +EL++   E
Sbjct: 1641 KDQVIKFQEGKVMILEQHGTSQVRSLLVDLDHMKGNLKEKNLELMSLNQQIKELEMEREE 1700

Query: 1088 QDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKV-QE 1146
                   L++ +        +++       +     +                 L + ++
Sbjct: 1701 VKSLHTSLEQLRAVLRDRENESDSQRDQLRLFQQYKEHQEEYLQELQDKVEKMTLSLSKK 1760

Query: 1147 EEEFIQERSVLQEQSAKLNTELQECYTKIIQ-LETLNTELTGHDVVNQEQINQLKSKLEQ 1205
            ++E   ++  +QE    +  +L+    ++ Q LETL  +    D+  Q Q  + + K EQ
Sbjct: 1761 DQELESQQKQIQEAEEVMEKKLKTVCDQLEQTLETLKEKERLLDIQKQ-QTREYEEKTEQ 1819

Query: 1206 LNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFE 1265
            +N    +L  T A LR        Q+  E+ E +++   Q +   Q+ E    ++ +  E
Sbjct: 1820 MNVLCRDLEYTKAILREKDLMIESQK--ELIETFQK---QEDDSMQQKEILQHLKGALKE 1874

Query: 1266 SKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRS 1325
             + E L    Q    +E  +    +Q T++  KLQ  E  L    ++ A +   ++ L+ 
Sbjct: 1875 QEQETLSLRKQCEAFKEKEEKHKTDQTTAIVQKLQCAESSLAARDQEIASLKEHVQELQK 1934

Query: 1326 EIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXX 1385
            + E E                      +   Q  KQ ++ ++ +I EE+ ++   S    
Sbjct: 1935 QKESEAKQVKSLQQDLNKMSKTMK---KNNLQILKQSEQINVFHICEESRKVALLSCQNQ 1991

Query: 1386 XXXXXXXXRVNDAEAKVL--ELTHQLE-LKDSEIYQKTHEYTITLTQRNDEFENVRQQLV 1442
                    R  D + + L  +L HQ E LK  +  Q          +R+ E E   ++ +
Sbjct: 1992 VSLLEEVVRKRDEDNETLLQKLQHQEEELKTLQNLQLMLSEKKEEIKRHGEEEKFPEEAL 2051

Query: 1443 ---EYEKRIEDLTYEKESELAILRLKMHENANHYETM--QKESEI----ERVKLIE---- 1489
               E+E + +    +K+SE   +R  +HE+  + +    +K+ EI    +RVK +E    
Sbjct: 2052 HGSEWETKAQG--EQKKSEDEEIR-GLHEDLQYVQQTLTKKDEEIKYQRDRVKYLEKTLA 2108

Query: 1490 ---ELNVKITES-----VSLNKQVAELNKALEEEVA---KTNEMQTALENQEIEIVTLND 1538
               EL  ++ +        L + +A L +    E+    K   +  AL   E+   TL +
Sbjct: 2109 GQKELAQQLEDERKVKGEELKRVIAILKQTESGEIEWKEKAQALTLALSKSEMTNGTLRE 2168

Query: 1539 EITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELL 1581
            EI  LQ+MV +   K + H+  + +  +     L N + K  L
Sbjct: 2169 EIAILQSMV-SERDKDRFHLQSSPELLKELQSLLLNQVQKASL 2210



 Score =  109 bits (262), Expect = 6e-22
 Identities = 241/1291 (18%), Positives = 531/1291 (41%), Gaps = 91/1291 (7%)

Query: 328  IELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKK-GSPLISRKSGRNTASKM---- 382
            I  L+H + Q  +  K+L+ +L  +  E+K  +S  +   S +++ K       K+    
Sbjct: 375  ISFLQHQHRQQEEKCKKLQQRLEQLEEENKMSNSHQQHLKSLVLALKCDCENLEKIRGEL 434

Query: 383  --KSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXX 440
              K   S+  +  L Q   +   K + A+ E V Q L  +    ++ +  KD        
Sbjct: 435  QQKLELSEQEASRLRQSNTELQLKEDSAQGEKVEQQLAMERAHHDHELVLKDLAALEEKH 494

Query: 441  XXXGKDTLIAQLQLEHQQHMEGPSL----IHVGTNTEDVNEIAKVQEQLKQELNDEIKDV 496
                 + + A+ +LE + H++   L      +    E   +        + +LN EI D+
Sbjct: 495  SLLQNELVAAREKLE-ESHLQRDLLKQEKHELTVALEKAEKSVAALTGAQNKLNSEIADL 553

Query: 497  NVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKL---KLKQMQKT-IDNFSKVSD 552
            +      K+ S  E +    D+++  NK +++++  ++L   K+ +M++  +    K++ 
Sbjct: 554  HT--AAAKMSSINEALAL--DKVE-LNKLVLQLEQENELLSDKVNEMERAKVSEQEKITL 608

Query: 553  SNKEIVRLTEELHHLSQ--KVAELEEEKGNLQLHLVDYDSGRMIE--SDVYKK------- 601
              +    L  E  HL +  K AE ++E+  +QL ++  +    +E  + VY++       
Sbjct: 609  YKRTNEELCAEKSHLEKLLKKAEEQQEELQMQLRILAEEKEETLEKLNQVYRQQESASSG 668

Query: 602  MIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVE-DKLA---DISQLQSDQVCS 657
            + ++   +  +  A++ +  +K  LV E   L+ +   VE D+      +++ +S +   
Sbjct: 669  LEQLRQQSSRQEDAVAKVSKEKEFLVHEKAALEVRLAAVERDRQGLSEQLAEARSVKDTL 728

Query: 658  EIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIK----DLENDKEDIMNKLQNY 713
            E      ++Q+  L  +K +L + +  +   KE + G +K    +LE ++  +  + +N 
Sbjct: 729  ESSLFEAQQQLSHLEITKSQLEIQLHTVVQAKEVIQGEVKCLQYELETERCLMKQEQKNM 788

Query: 714  IQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQER-DLYIENIESELS 772
             Q  + + ++       + ++   +IN   Q     + G   ++QER +L+ +       
Sbjct: 789  AQRLIQIEEQHNNTLKLQQTDHEVEINKLLQDLASEREGRQLELQERLELWEKEKAEAEG 848

Query: 773  KYKSRICRLEESIAVM----EDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLA 828
            +++ ++  ++E +A M    E+ R  +E    ++ +  + ++KA  E  +Q    +    
Sbjct: 849  QHEKKLFHMKEKVATMQAQQEEERTRVESANQEILTEKENEKKALLETLLQTQGELTEAC 908

Query: 829  VLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDL 888
              ++  R   K+  E E   + + +K Q  L+E  + +I + +   H   +       ++
Sbjct: 909  HQLEQLRQEVKEQQEYE---QNITEKLQAELQET-HCKIKMVE-NMHKEEMENIKEEKNI 963

Query: 889  AESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEI-EDLEIEFNTQIESAIRDKKVLN 947
               +    Q Q+ +L S L      HQ +  + ++E+ E  E+     +ES  R++  L+
Sbjct: 964  LLQQRDDLQKQVEELTSQLAASEESHQAIGHKAQQELSEAQELSRQKALESE-RERLSLS 1022

Query: 948  EKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQY 1007
             + +K +   T  E  L + +N +  L+  +++  +++ +   + +Q+   Q     E  
Sbjct: 1023 LE-QKELSLKTLEENNLVQ-QNEVSKLHSAIQQAQQLHSD-HRREIQELNNQVQTLQEVV 1079

Query: 1008 INEINKLNALLKQ--KD-EEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEM 1064
            + +   L A  KQ  +D EE  A  + + ++     + +++   +L     + + +  E 
Sbjct: 1080 LEKEASLAAREKQLLQDLEESRAGERCLRDSLHVLEAEMAELHLRLCSTENRAKALATEC 1139

Query: 1065 QRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDD 1124
            Q+ +    +++   ++L +++        +     + +        G+ +S   +   + 
Sbjct: 1140 QQANNAHCEAQSQLDKLHLVLHHVLCDSTDKSRDLVAWSSEQDHVWGLTVSQAKDLHVE- 1198

Query: 1125 ANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTE 1184
               VD            LK Q +++       +Q+    L  EL +   +       N E
Sbjct: 1199 -LTVDRVAAALQDLRQDLK-QTQQDLNDAGKKVQD----LELELSKRQAERDHFSAHNQE 1252

Query: 1185 LTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLA 1244
            L      +QE  +  K++   L  E   L   VA L   + SA  Q+   + E  +  L 
Sbjct: 1253 LQKQLAQSQEVFSGWKAEAAALKKEAITLHQEVASLERKLESAEKQKKDVLHE--RDRLQ 1310

Query: 1245 QREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKE- 1303
              E         L+  ++A E++     D   S  QE    + T   V   +NK  D + 
Sbjct: 1311 AVEEKLMWEIKILQESVTASETRANTAADMNHSLEQE----LQTTLSVLKTKNKEVDAQW 1366

Query: 1304 EHLRNLQEKYADV------INQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQ 1357
            E ++ LQ++ ADV      + Q+  + S+ E E   +                 L    +
Sbjct: 1367 EKIQMLQKEAADVKALQENLIQVNAILSKREGEMKLYQEQMRMLENQKEMHKTTLDQVIK 1426

Query: 1358 SYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQL-ELKDSEI 1416
              K+ +E++  +  E+  +L+K               + D + ++     ++ EL+  + 
Sbjct: 1427 DIKEKKEKT-ESQQEQIQELEKQQELQRTVISKMSKDLEDRDKEIRSQQEEIWELEKQQE 1485

Query: 1417 YQKT--HEYTITLTQRNDEFENVRQQLVEYEKRIE---DLTYEKESELAILRLKMHENAN 1471
             Q+T   + T  L  R+ E ++ ++++ E EK  E       +   +L     K+     
Sbjct: 1486 LQRTVVSKMTKDLAHRDQEIQSQQEEIQELEKERELQRTAASKMSKDLKERDEKIRSQQE 1545

Query: 1472 HYETMQKESEIERV---KLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALEN 1528
              E ++K+ E++R    K+ + L  +  E  S  + + EL K  E +    ++M   LE 
Sbjct: 1546 LIEELEKQQELQRTALSKMSKNLEERDQEIKSQQELIEELKKQQELQRTAVSKMNKDLEE 1605

Query: 1529 QEIEIVTLNDEITNLQ---NMVRASSSKIQK 1556
            ++ EI +  +EI  L+    + R   SK+ K
Sbjct: 1606 RDQEIRSQQEEIQELEKQRELQRTILSKMSK 1636



 Score = 88.2 bits (209), Expect = 2e-15
 Identities = 228/1182 (19%), Positives = 492/1182 (41%), Gaps = 129/1182 (10%)

Query: 480  KVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQ 539
            + Q+Q+++E+N E  +V    + E L+  E     L D +   +  +++ +  ++ K K 
Sbjct: 215  QAQQQVEREINQEALEVMCLQVDEDLEKKE-----LQDRVMELSALLVQSQKQNEEKEKT 269

Query: 540  MQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVY 599
            + KT+++  ++ +++    RL  E+ + +      +EE   LQ  + +     + +SD  
Sbjct: 270  V-KTLNDTVEMLEAS----RL--EVEYEASLTKNAKEENLALQKLIKEITEVVLDDSDST 322

Query: 600  KKMIEMENLAETRLKAISLLESQK-FDLVQELHILQQKY-----DEVEDKLADISQLQSD 653
              +++    +   L  +S L+++  F LVQE    +QK      +E+  +   IS LQ  
Sbjct: 323  VGIVQRPESSNV-LSCLSSLDAEHAFVLVQETLARRQKAIQALKEELSTRQDSISFLQHQ 381

Query: 654  QVCSEIKSVHLEEQIDALSASKK-------ELALVIENLKLDKEQLYGTIKDLENDKEDI 706
                E K   L+++++ L    K        L  ++  LK D E L     +L+   E  
Sbjct: 382  HRQQEEKCKKLQQRLEQLEEENKMSNSHQQHLKSLVLALKCDCENLEKIRGELQQKLELS 441

Query: 707  MNKLQNYIQENMDLTDKLEKMSAEKISELLA--KINH-------------EEQSKIQTQF 751
              +     Q N +L  K +    EK+ + LA  + +H             E+ S +Q + 
Sbjct: 442  EQEASRLRQSNTELQLKEDSAQGEKVEQQLAMERAHHDHELVLKDLAALEEKHSLLQNEL 501

Query: 752  -GIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQ 810
                 K++E  L  + ++ E  +    + + E+S+A +   +  L  +   L +   +  
Sbjct: 502  VAAREKLEESHLQRDLLKQEKHELTVALEKAEKSVAALTGAQNKLNSEIADLHTAAAKMS 561

Query: 811  KAYSEYTIQEDELVNRLAVLMDH------DRVVEKQLLEI-EHENKELQKK-NQILLEEN 862
                   + + EL N+L + ++       D+V E +  ++ E E   L K+ N+ L  E 
Sbjct: 562  SINEALALDKVEL-NKLVLQLEQENELLSDKVNEMERAKVSEQEKITLYKRTNEELCAEK 620

Query: 863  QNLQISL-------SDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQ 915
             +L+  L        ++Q     L E+   T    ++  + Q         L++ +   +
Sbjct: 621  SHLEKLLKKAEEQQEELQMQLRILAEEKEETLEKLNQVYRQQESASSGLEQLRQQSSRQE 680

Query: 916  TLIVQKKKEIEDLEIE---FNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIE 972
              + +  KE E L  E      ++ +  RD++ L+E+  +       LE+ L E +  + 
Sbjct: 681  DAVAKVSKEKEFLVHEKAALEVRLAAVERDRQGLSEQLAEARSVKDTLESSLFEAQQQLS 740

Query: 973  NLNMNVEELN-KMNLELIDKHVQKQQTQSPDY---TEQYINEINKLNAL-----LKQKDE 1023
            +L +   +L  +++  +  K V + + +   Y   TE+ + +  + N       ++++  
Sbjct: 741  HLEITKSQLEIQLHTVVQAKEVIQGEVKCLQYELETERCLMKQEQKNMAQRLIQIEEQHN 800

Query: 1024 EIIALNQKINNAQVSYM--SMVSDYESKLAQFTTKLENMEEEMQRV----SKQLLDSKQH 1077
              + L Q  +  +++ +   + S+ E +  +   +LE  E+E         K+L   K+ 
Sbjct: 801  NTLKLQQTDHEVEINKLLQDLASEREGRQLELQERLELWEKEKAEAEGQHEKKLFHMKEK 860

Query: 1078 NEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXX 1137
               +Q    E+  +++   +  LT + N  K     +  T   +++  + ++        
Sbjct: 861  VATMQAQQEEERTRVESANQEILTEKENEKKALLETLLQTQGELTEACHQLEQLRQ---- 916

Query: 1138 XXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQIN 1197
                 +V+E++E+  E+++ +    KL  ELQE + KI  +E +          ++E++ 
Sbjct: 917  -----EVKEQQEY--EQNITE----KLQAELQETHCKIKMVENM----------HKEEME 955

Query: 1198 QLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQ-READFQKTEHE 1256
             +K +   L  + D+L   V EL S + +A ++    I    +Q L++ +E   QK    
Sbjct: 956  NIKEEKNILLQQRDDLQKQVEELTSQL-AASEESHQAIGHKAQQELSEAQELSRQKALES 1014

Query: 1257 LRVQLSAFESKYEQLLDSVQSST---QEETNKI-VTMEQVTSL----QNKLQDKEEHLRN 1308
             R +LS    + E  L +++ +    Q E +K+   ++Q   L    + ++Q+    ++ 
Sbjct: 1015 ERERLSLSLEQKELSLKTLEENNLVQQNEVSKLHSAIQQAQQLHSDHRREIQELNNQVQT 1074

Query: 1309 LQ----EKYADVINQIEILRSEIEDEKVAFX-XXXXXXXXXXXXXXXDLR---TENQSYK 1360
            LQ    EK A +  + + L  ++E+ +                     LR   TEN++  
Sbjct: 1075 LQEVVLEKEASLAAREKQLLQDLEESRAGERCLRDSLHVLEAEMAELHLRLCSTENRAKA 1134

Query: 1361 QMQE-QSILNIN-EENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQ 1418
               E Q   N + E  +QL K              +  D  A   E  H   L  S+   
Sbjct: 1135 LATECQQANNAHCEAQSQLDKLHLVLHHVLCDSTDKSRDLVAWSSEQDHVWGLTVSQ--A 1192

Query: 1419 KTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQK 1478
            K     +T+ +     +++RQ L + ++ + D   +K  +L +   K     +H+    +
Sbjct: 1193 KDLHVELTVDRVAAALQDLRQDLKQTQQDLND-AGKKVQDLELELSKRQAERDHFSAHNQ 1251

Query: 1479 ESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLND 1538
            E + +  +  E  +    E+ +L K+       L +EVA       + E Q+ +++   D
Sbjct: 1252 ELQKQLAQSQEVFSGWKAEAAALKKEAI----TLHQEVASLERKLESAEKQKKDVLHERD 1307

Query: 1539 EITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKEL 1580
             +  ++  +      +Q+ V+ AS+T+      +++++ +EL
Sbjct: 1308 RLQAVEEKLMWEIKILQESVT-ASETRANTAADMNHSLEQEL 1348



 Score = 74.1 bits (174), Expect = 3e-11
 Identities = 189/974 (19%), Positives = 408/974 (41%), Gaps = 94/974 (9%)

Query: 215  KQQMTKMQENFIAMEAEWKDEKQRLL-----KDIESKDVRISSLEEANKLLEAARFEISL 269
            K++ T+ Q+  I  E E + E QR +     KD+E +D  I S +E    LE  +     
Sbjct: 1431 KKEKTESQQEQI-QELEKQQELQRTVISKMSKDLEDRDKEIRSQQEEIWELEKQQELQRT 1489

Query: 270  EHSKLAQELEQXXXXXXXXXXXXXXLAKQ-SIEPSCEEKTEIEEKGSLE-IANMTELTKK 327
              SK+ ++L                L K+  ++ +   K   + K   E I +  EL ++
Sbjct: 1490 VVSKMTKDLAHRDQEIQSQQEEIQELEKERELQRTAASKMSKDLKERDEKIRSQQELIEE 1549

Query: 328  IELLEHLN-CQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPW 386
            +E  + L    + + +K LE +   + ++ + +    K+      ++  R   SKM    
Sbjct: 1550 LEKQQELQRTALSKMSKNLEERDQEIKSQQELIEELKKQ------QELQRTAVSKMNKDL 1603

Query: 387  SQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGK- 445
             +   E  +Q  + +  + +      ++  ++KDL +K+ VI  ++            + 
Sbjct: 1604 EERDQEIRSQQEEIQELEKQRELQRTILSKMSKDLEEKDQVIKFQEGKVMILEQHGTSQV 1663

Query: 446  -------DTLIAQLQLEHQQHME-GPSLIHVGTNTEDVNEIAKVQEQLKQELND-EIKDV 496
                   D +   L+ ++ + M     +  +    E+V  +    EQL+  L D E +  
Sbjct: 1664 RSLLVDLDHMKGNLKEKNLELMSLNQQIKELEMEREEVKSLHTSLEQLRAVLRDRENESD 1723

Query: 497  NVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKE 556
            + +D +   +  +E   +   E+    + M    S    +L+  QK I    +V +   +
Sbjct: 1724 SQRDQLRLFQQYKEHQEEYLQELQDKVEKMTLSLSKKDQELESQQKQIQEAEEVMEKKLK 1783

Query: 557  IV--RLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDV-YKKMI--EMENLAET 611
             V  +L + L  L +K   L+ +K   + +    +   ++  D+ Y K I  E + + E+
Sbjct: 1784 TVCDQLEQTLETLKEKERLLDIQKQQTREYEEKTEQMNVLCRDLEYTKAILREKDLMIES 1843

Query: 612  RLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDAL 671
            + + I   + Q+ D +Q+  ILQ     ++++  +   L+    C   K    + + D  
Sbjct: 1844 QKELIETFQKQEDDSMQQKEILQHLKGALKEQEQETLSLRKQ--CEAFKEKEEKHKTDQT 1901

Query: 672  SASKKELALVIENLKL-DKE--QLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMS 728
            +A  ++L     +L   D+E   L   +++L+  KE    ++++ +Q++++   K  K +
Sbjct: 1902 TAIVQKLQCAESSLAARDQEIASLKEHVQELQKQKESEAKQVKS-LQQDLNKMSKTMKKN 1960

Query: 729  AEKISELLAKIN--H--EEQSKI-----QTQFG-IDAKIQERDLYIENIESELSKYKSRI 778
              +I +   +IN  H  EE  K+     Q Q   ++  +++RD   E +  +L   +  +
Sbjct: 1961 NLQILKQSEQINVFHICEESRKVALLSCQNQVSLLEEVVRKRDEDNETLLQKLQHQEEEL 2020

Query: 779  CRLEESIAVMEDRRYSLERKADQLGSYLQE-------KQKAYSEYTIQEDELVNRL---- 827
              L+    ++ +++  ++R  ++   + +E       + KA  E    EDE +  L    
Sbjct: 2021 KTLQNLQLMLSEKKEEIKRHGEE-EKFPEEALHGSEWETKAQGEQKKSEDEEIRGLHEDL 2079

Query: 828  ------------AVLMDHDRV--VEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQ 873
                         +    DRV  +EK L   +   ++L+ + ++  EE + +   L   +
Sbjct: 2080 QYVQQTLTKKDEEIKYQRDRVKYLEKTLAGQKELAQQLEDERKVKGEELKRVIAILKQTE 2139

Query: 874  QHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEH--QTLIVQKKKE-IEDLEI 930
                   EKA    LA S+S      LR+  + L+ +  E       +Q   E +++L+ 
Sbjct: 2140 SGEIEWKEKAQALTLALSKSEMTNGTLREEIAILQSMVSERDKDRFHLQSSPELLKELQS 2199

Query: 931  EFNTQIESA-IRD-----KKVLNEKYEK----NIEYVTQ--LEAQLQEYKNNIENLNMNV 978
                Q++ A + D     KK LN+ + +    ++ ++ +  L  +L+  +  +  L    
Sbjct: 2200 LLLNQVQKASLADIMKEGKKGLNDVHAQGWSPSLTFLEKKLLWQRLECLQQAVARLEHEK 2259

Query: 979  EELNKMNLEL-IDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQK-----I 1032
             EL ++N+EL I     +++ +    +  + ++ N     L + DE+ +  ++K     +
Sbjct: 2260 SELKQLNVELKITLEQVERERRRLKRSCSHQSQPNANRFSLSESDEDKMPASRKEEARAL 2319

Query: 1033 NNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQH-NEELQILVREQDDQ 1091
             +      + V+  + +LAQ     ++  E   + S++LLD  Q  +  L+ ++RE    
Sbjct: 2320 CSQLAELQNQVTLLQQQLAQERKYKQDYIECCAKTSQELLDLHQELSYSLEAVIREPKAA 2379

Query: 1092 IKELKETKLTFEMN 1105
            + E +  KL   +N
Sbjct: 2380 VLEAETQKLDLSLN 2393



 Score = 71.3 bits (167), Expect = 2e-10
 Identities = 167/813 (20%), Positives = 332/813 (40%), Gaps = 89/813 (10%)

Query: 818  IQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYN 877
            +Q  E  N L+ L   D   E   + ++      QK  Q L EE    Q S+S +Q  + 
Sbjct: 326  VQRPESSNVLSCLSSLD--AEHAFVLVQETLARRQKAIQALKEELSTRQDSISFLQHQHR 383

Query: 878  ALVEKAN----RTDLAESE---STKYQTQLRDLE-------SNLKRITHEHQTLIVQKKK 923
               EK      R +  E E   S  +Q  L+ L         NL++I  E Q  +   ++
Sbjct: 384  QQEEKCKKLQQRLEQLEEENKMSNSHQQHLKSLVLALKCDCENLEKIRGELQQKLELSEQ 443

Query: 924  EIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNK 983
            E   L  + NT+++  +++     EK E+ +     +E    +++  +++L    E+ + 
Sbjct: 444  EASRLR-QSNTELQ--LKEDSAQGEKVEQQLA----MERAHHDHELVLKDLAALEEKHSL 496

Query: 984  MNLELIDKHVQKQQTQ-SPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSM 1042
            +  EL+    + +++    D  +Q   E ++L   L++ ++ + AL      AQ    S 
Sbjct: 497  LQNELVAAREKLEESHLQRDLLKQ---EKHELTVALEKAEKSVAALT----GAQNKLNSE 549

Query: 1043 VSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTF 1102
            ++D  +  A+ ++  E +  +   ++K +L  +Q NE L   V E + + K  ++ K+T 
Sbjct: 550  IADLHTAAAKMSSINEALALDKVELNKLVLQLEQENELLSDKVNEME-RAKVSEQEKITL 608

Query: 1103 EMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSA 1162
                 + E     S +E +   A                +  +E+EE +++ + +  Q  
Sbjct: 609  YKRTNE-ELCAEKSHLEKLLKKAEEQQEELQMQLR----ILAEEKEETLEKLNQVYRQQE 663

Query: 1163 KLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRS 1222
              ++ L++   +  + E    +++        +   L+ +L  +  +   L   +AE RS
Sbjct: 664  SASSGLEQLRQQSSRQEDAVAKVSKEKEFLVHEKAALEVRLAAVERDRQGLSEQLAEARS 723

Query: 1223 SISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQE- 1281
             +   ++   FE     +Q L+  E     T+ +L +QL       E +   V+    E 
Sbjct: 724  -VKDTLESSLFEA----QQQLSHLEI----TKSQLEIQLHTVVQAKEVIQGEVKCLQYEL 774

Query: 1282 ETNK-IVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXX 1340
            ET + ++  EQ    Q  +Q +E+H   L+ +  D   +I  L  ++  E+         
Sbjct: 775  ETERCLMKQEQKNMAQRLIQIEEQHNNTLKLQQTDHEVEINKLLQDLASEREGRQLELQE 834

Query: 1341 XXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEA 1400
                          E    +   E+ + ++ E+ A ++               RV  A  
Sbjct: 835  RLELW-------EKEKAEAEGQHEKKLFHMKEKVATMQAQQEEERT-------RVESANQ 880

Query: 1401 KVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESEL- 1459
            ++L    + E +   + +   +    LT+   + E +RQ++ E ++  +++T + ++EL 
Sbjct: 881  EILT---EKENEKKALLETLLQTQGELTEACHQLEQLRQEVKEQQEYEQNITEKLQAELQ 937

Query: 1460 -AILRLKMHENANHYETMQKESEIERV---------KLIEELNVKITESVSLNKQVA--- 1506
                ++KM EN  H E M+   E + +         K +EEL  ++  S   ++ +    
Sbjct: 938  ETHCKIKMVENM-HKEEMENIKEEKNILLQQRDDLQKQVEELTSQLAASEESHQAIGHKA 996

Query: 1507 --ELNKALEEEVAKTNE-----MQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVS 1559
              EL++A E    K  E     +  +LE +E+ + TL +     QN V    S IQ+   
Sbjct: 997  QQELSEAQELSRQKALESERERLSLSLEQKELSLKTLEENNLVQQNEVSKLHSAIQQAQQ 1056

Query: 1560 FASDTKQGRDEQLDNTMNKELLDAVPRAELDLA 1592
              SD +  R+ Q  N   + L + V   E  LA
Sbjct: 1057 LHSDHR--REIQELNNQVQTLQEVVLEKEASLA 1087


>UniRef50_Q57UD0 Cluster: Kinesin K39, putative; n=1; Trypanosoma
            brucei|Rep: Kinesin K39, putative - Trypanosoma brucei
          Length = 1803

 Score =  123 bits (297), Expect = 4e-26
 Identities = 212/1187 (17%), Positives = 494/1187 (41%), Gaps = 82/1187 (6%)

Query: 445  KDTLIAQLQLEHQ-QHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELND---EIKDVNVKD 500
            ++ LI   +LE Q +  +  +  H   +    +E A+ +++L +++     EI+ +  + 
Sbjct: 489  EELLIKATELERQVEESKRRAEYHEEMSQRLKDEYAQREQELLEKVRQHRAEIEGIRERK 548

Query: 501  LIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRL 560
              E L S+++Q++++  E++    +  +     + + +Q+   + N  + S+ + E+ + 
Sbjct: 549  DAEML-SSQQQLSRVMSELEQERHSREEALHILRERQEQLSAALCNSQQSSEKHTELQQQ 607

Query: 561  TEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKM-IEMENLAETRLKAIS-L 618
             EEL H  QK+ E  E +  +   L  +   R    ++ + + +++E      +K I+ L
Sbjct: 608  NEELSHRMQKLLEECEAQQRILSDLEVFRLERNELEEIAQFLDLKLEETEHRHIKTINHL 667

Query: 619  LESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKEL 678
            L +     + +  +L     EVE +L   +Q   DQ  +  K+ H   Q++    +KK L
Sbjct: 668  LTTIGMHNLWQAELLTAVGTEVETQLTKCNQHHFDQRAAMEKN-HKLFQMEQHQMTKK-L 725

Query: 679  ALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEK--ISELL 736
               I  L+ + E+    +   +  +  I NK +        +   LE + AE+  + + L
Sbjct: 726  EQKILMLEKEIEEAKKQLDTTKQSEAAITNKARQAEDARAAVERNLETVEAERDELQQRL 785

Query: 737  AKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICR----LEESIAVMEDRR 792
               +++ +S+++      A + ER+L  E +E+E ++ + R+      L+  +   ED R
Sbjct: 786  DATSNDLKSQLRNSEDARAAV-ERNL--ETVEAERNELQQRLDATSNDLKSQLRNSEDAR 842

Query: 793  YSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQ 852
             ++ER  + + +   E+ +         ++L ++L    D    VE+ L  +E E  ELQ
Sbjct: 843  AAVERNLETVEA---ERNELQQRLDATSNDLKSQLRNSEDARAAVERNLETVEAERNELQ 899

Query: 853  KK----NQILLEENQNLQISLSDMQQHYNAL-VEKANRTDLAESESTKYQTQLRDLESNL 907
            ++    +  L  + +N + + + ++++   +  E+       ++ S   ++QLR+ E   
Sbjct: 900  QRLDATSNDLKSQLRNSEDARAAVERNLETVEAERNELQQRLDATSNDLKSQLRNSEDAR 959

Query: 908  KRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYV----TQLEAQ 963
              +    +T+  ++ +  + L+   N  ++S +R+ +      E+N+E V     +L+ +
Sbjct: 960  AAVERNLETVEAERNELQQRLDATSN-DLKSQLRNSEDARAAVERNLETVEAERNELQQR 1018

Query: 964  LQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDE 1023
            L    N++++   N E+        ++++++  + +  +  ++     N L + L+  ++
Sbjct: 1019 LDATSNDLKSQLRNSEDAR----AAVERNLETVEAERNELQQRLDATSNDLKSQLRNSED 1074

Query: 1024 EIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQ- 1082
               A+ + +   +     +    ++      ++L N E+    V + L   +    ELQ 
Sbjct: 1075 ARAAVERNLETVEAERNELQQRLDATSNDLKSQLRNSEDARAAVERNLETVEAERNELQQ 1134

Query: 1083 ---ILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXX 1139
                   +   Q++  ++ +   E N+   E     + ++   D  +N D          
Sbjct: 1135 RLDATSNDLKSQLRNSEDARAAVERNLETVEAE--RNELQQRLDATSN-DLKSQLRNSED 1191

Query: 1140 XXLKVQEEEEFIQ-ERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQ 1198
                V+   E ++ ER+ LQ+   +L+    +  +++   E     +  +    + + N+
Sbjct: 1192 ARAAVERNLETVEAERNELQQ---RLDATSNDLKSQLRNSEDARAAVERNLETVEAERNE 1248

Query: 1199 LKSKLEQLNTENDNLLSTVAELRSSISS-AVDQRGFEIAELWKQHLAQREADFQKTEHEL 1257
            L+ +L+   T ND      ++LR+S  + A  +R  E  E  +  L QR      T ++L
Sbjct: 1249 LQQRLDA--TSND----LKSQLRNSEDARAAVERNLETVEAERNELQQR---LDATSNDL 1299

Query: 1258 RVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVI 1317
            + QL   E     +  +++ + + E N++      TS      D +  LRN ++  A V 
Sbjct: 1300 KSQLRNSEDARAAVERNLE-TVEAERNELQQRLDATS-----NDLKSQLRNSEDARAAVE 1353

Query: 1318 NQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQL 1377
              +E + +E  +                      LR  ++  +   E+++  +  E  +L
Sbjct: 1354 RNLETVEAERNE-------LQQRLDATSNDLKSQLR-NSEDARAAVERNLETVEAERNEL 1405

Query: 1378 KKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENV 1437
            ++                 DA A V      +E + +E+ Q+      T      +  N 
Sbjct: 1406 QQRLDATSNDLKSQLRNSEDARAAVERNLETVEAERNELQQR---LDATSNDLKSQLRNS 1462

Query: 1438 RQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITE 1497
                   E+ +E +    E+E   L+ ++   +N  ++  + SE  R  +   L     E
Sbjct: 1463 EDARAAVERNLETV----EAERNELQQRLDATSNDLKSQLRNSEDARAAVERNLETVEAE 1518

Query: 1498 SVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKH 1557
               L +++   +  L+ ++  + + + A+E     + T+  E   LQ  + A+S+ ++  
Sbjct: 1519 RNELQQRLDATSNDLKSQLRNSEDARAAVER---NLETVEAERNELQQRLDATSNDLKSQ 1575

Query: 1558 VSFASDTKQGRDEQLD--NTMNKELLDAVPRAELDLAMYMLHQRDVR 1602
            +  + D +   +  L+       EL   +     DL   + +  D R
Sbjct: 1576 LRNSEDARAAVERNLETVEAERNELQQRLDATSNDLKSQLRNSEDAR 1622



 Score = 98.7 bits (235), Expect = 1e-18
 Identities = 183/1115 (16%), Positives = 467/1115 (41%), Gaps = 85/1115 (7%)

Query: 234  DEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXX 293
            + +QR+L D+E   +  + LEE  + L+    E    H K    L               
Sbjct: 623  EAQQRILSDLEVFRLERNELEEIAQFLDLKLEETEHRHIKTINHLLTTIGMHNLWQAELL 682

Query: 294  XLAKQSIEPSCEE--KTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLAT 351
                  +E    +  +   +++ ++E  +     ++ ++ + L  +I    KE+E     
Sbjct: 683  TAVGTEVETQLTKCNQHHFDQRAAMEKNHKLFQMEQHQMTKKLEQKILMLEKEIEEAKKQ 742

Query: 352  MGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKIN--KNEIAK 409
            + T  ++ ++ + K      +      A +      +   + L Q  D   N  K+++  
Sbjct: 743  LDTTKQSEAAITNKA----RQAEDARAAVERNLETVEAERDELQQRLDATSNDLKSQLRN 798

Query: 410  LEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVG 469
             E    ++ ++L   E V +E++                  + QL + +        ++ 
Sbjct: 799  SEDARAAVERNL---ETVEAERNELQQRLDATSND-----LKSQLRNSEDARAAVERNLE 850

Query: 470  TNTEDVNEIAKVQEQLKQELNDEIKD-VNVKDLIEK-LKSAEEQITQLNDEIDAANKNMI 527
            T   + NE+ +  +    +L  ++++  + +  +E+ L++ E +  +L   +DA + ++ 
Sbjct: 851  TVEAERNELQQRLDATSNDLKSQLRNSEDARAAVERNLETVEAERNELQQRLDATSNDLK 910

Query: 528  KVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVD 587
                N +     +++ ++     ++ N+   RL    + L  ++   E+ +  ++ +L  
Sbjct: 911  SQLRNSEDARAAVERNLETVE--AERNELQQRLDATSNDLKSQLRNSEDARAAVERNLET 968

Query: 588  YDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKL-AD 646
             ++ R   +++ +++    N  +++L+     E  +  + + L  ++ + +E++ +L A 
Sbjct: 969  VEAER---NELQQRLDATSNDLKSQLRN---SEDARAAVERNLETVEAERNELQQRLDAT 1022

Query: 647  ISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDI 706
             + L+S    SE     +E  ++ + A + EL    + L      L   +++ E+ +  +
Sbjct: 1023 SNDLKSQLRNSEDARAAVERNLETVEAERNELQ---QRLDATSNDLKSQLRNSEDARAAV 1079

Query: 707  MNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIEN 766
               L+    E  +L  +L+  S    ++L +++ + E ++   +  ++    ER+   + 
Sbjct: 1080 ERNLETVEAERNELQQRLDATS----NDLKSQLRNSEDARAAVERNLETVEAERNELQQR 1135

Query: 767  IESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNR 826
            +++  +  KS++   E++ A +E    ++E + ++    LQ++  A S      ++L ++
Sbjct: 1136 LDATSNDLKSQLRNSEDARAAVERNLETVEAERNE----LQQRLDATS------NDLKSQ 1185

Query: 827  LAVLMDHDRVVEKQLLEIEHENKELQKK----NQILLEENQNLQISLSDMQQHYNAL-VE 881
            L    D    VE+ L  +E E  ELQ++    +  L  + +N + + + ++++   +  E
Sbjct: 1186 LRNSEDARAAVERNLETVEAERNELQQRLDATSNDLKSQLRNSEDARAAVERNLETVEAE 1245

Query: 882  KANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIR 941
            +       ++ S   ++QLR+ E     +    +T+  ++ +  + L+   N  ++S +R
Sbjct: 1246 RNELQQRLDATSNDLKSQLRNSEDARAAVERNLETVEAERNELQQRLDATSN-DLKSQLR 1304

Query: 942  DKKVLNEKYEKNIEYV----TQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQ 997
            + +      E+N+E V     +L+ +L    N++++   N E+        ++++++  +
Sbjct: 1305 NSEDARAAVERNLETVEAERNELQQRLDATSNDLKSQLRNSEDAR----AAVERNLETVE 1360

Query: 998  TQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKL 1057
             +  +  ++     N L + L+  ++   A+ + +   +     +    ++      ++L
Sbjct: 1361 AERNELQQRLDATSNDLKSQLRNSEDARAAVERNLETVEAERNELQQRLDATSNDLKSQL 1420

Query: 1058 ENMEEEMQRVSKQLLDSKQHNEELQ----ILVREQDDQIKELKETKLTFEMNIPKTEGMI 1113
             N E+    V + L   +    ELQ        +   Q++  ++ +   E N+   E   
Sbjct: 1421 RNSEDARAAVERNLETVEAERNELQQRLDATSNDLKSQLRNSEDARAAVERNLETVEAE- 1479

Query: 1114 ISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQ-ERSVLQEQSAKLNTELQECY 1172
              + ++   D  +N D              V+   E ++ ER+ LQ+   +L+    +  
Sbjct: 1480 -RNELQQRLDATSN-DLKSQLRNSEDARAAVERNLETVEAERNELQQ---RLDATSNDLK 1534

Query: 1173 TKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISS-AVDQR 1231
            +++   E     +  +    + + N+L+ +L+   T ND      ++LR+S  + A  +R
Sbjct: 1535 SQLRNSEDARAAVERNLETVEAERNELQQRLDA--TSND----LKSQLRNSEDARAAVER 1588

Query: 1232 GFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQ 1291
              E  E  +  L QR      T ++L+ QL   E     +  +++ + + E N++     
Sbjct: 1589 NLETVEAERNELQQR---LDATSNDLKSQLRNSEDARAAVERNLE-TVEAERNELQQRLD 1644

Query: 1292 VTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSE 1326
             TS      D +  LRN ++  A V   +E + +E
Sbjct: 1645 ATS-----NDLKSQLRNSEDARAAVERNLETVEAE 1674



 Score = 97.5 bits (232), Expect = 3e-18
 Identities = 188/1149 (16%), Positives = 481/1149 (41%), Gaps = 85/1149 (7%)

Query: 145  THLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXX 204
            T L+   +   +  + ++   K+ +     + +K+ +K  ++E + +             
Sbjct: 691  TQLTKCNQHHFDQRAAMEKNHKLFQMEQHQMTKKLEQKILMLEKEIEEAKKQLDTTKQSE 750

Query: 205  XXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVR--ISSLEEANKLLEA 262
                      +     ++ N   +EAE  + +QRL  D  S D++  + + E+A   +E 
Sbjct: 751  AAITNKARQAEDARAAVERNLETVEAERDELQQRL--DATSNDLKSQLRNSEDARAAVER 808

Query: 263  ARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCE----EKTEIEEKGSLEI 318
                +  E ++L Q L+                A+ ++E + E    E+ E++++  L+ 
Sbjct: 809  NLETVEAERNELQQRLDATSNDLKSQLRNSED-ARAAVERNLETVEAERNELQQR--LD- 864

Query: 319  ANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNT 378
            A   +L  ++   E     + +  + +E +   +     A S+  K  S L + +  R  
Sbjct: 865  ATSNDLKSQLRNSEDARAAVERNLETVEAERNELQQRLDATSNDLK--SQLRNSEDAR-A 921

Query: 379  ASKMKSPWSQLSSETLNQDTDKKIN--KNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXX 436
            A +      +     L Q  D   N  K+++   E    ++ ++L   E V +E++    
Sbjct: 922  AVERNLETVEAERNELQQRLDATSNDLKSQLRNSEDARAAVERNL---ETVEAERNELQQ 978

Query: 437  XXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKD- 495
                          + QL + +        ++ T   + NE+ +  +    +L  ++++ 
Sbjct: 979  RLDATSND-----LKSQLRNSEDARAAVERNLETVEAERNELQQRLDATSNDLKSQLRNS 1033

Query: 496  VNVKDLIEK-LKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSN 554
             + +  +E+ L++ E +  +L   +DA + ++     N +     +++ ++     ++ N
Sbjct: 1034 EDARAAVERNLETVEAERNELQQRLDATSNDLKSQLRNSEDARAAVERNLETVE--AERN 1091

Query: 555  KEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLK 614
            +   RL    + L  ++   E+ +  ++ +L   ++ R   +++ +++    N  +++L+
Sbjct: 1092 ELQQRLDATSNDLKSQLRNSEDARAAVERNLETVEAER---NELQQRLDATSNDLKSQLR 1148

Query: 615  AISLLESQKFDLVQELHILQQKYDEVEDKL-ADISQLQSDQVCSEIKSVHLEEQIDALSA 673
                 E  +  + + L  ++ + +E++ +L A  + L+S    SE     +E  ++ + A
Sbjct: 1149 N---SEDARAAVERNLETVEAERNELQQRLDATSNDLKSQLRNSEDARAAVERNLETVEA 1205

Query: 674  SKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKIS 733
             + EL    + L      L   +++ E+ +  +   L+    E  +L  +L+  S    +
Sbjct: 1206 ERNELQ---QRLDATSNDLKSQLRNSEDARAAVERNLETVEAERNELQQRLDATS----N 1258

Query: 734  ELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRY 793
            +L +++ + E ++   +  ++    ER+   + +++  +  KS++   E++ A +E    
Sbjct: 1259 DLKSQLRNSEDARAAVERNLETVEAERNELQQRLDATSNDLKSQLRNSEDARAAVERNLE 1318

Query: 794  SLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQK 853
            ++E + ++    LQ++  A S      ++L ++L    D    VE+ L  +E E  ELQ+
Sbjct: 1319 TVEAERNE----LQQRLDATS------NDLKSQLRNSEDARAAVERNLETVEAERNELQQ 1368

Query: 854  K----NQILLEENQNLQISLSDMQQHYNAL-VEKANRTDLAESESTKYQTQLRDLESNLK 908
            +    +  L  + +N + + + ++++   +  E+       ++ S   ++QLR+ E    
Sbjct: 1369 RLDATSNDLKSQLRNSEDARAAVERNLETVEAERNELQQRLDATSNDLKSQLRNSEDARA 1428

Query: 909  RITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYV----TQLEAQL 964
             +    +T+  ++ +  + L+   N  ++S +R+ +      E+N+E V     +L+ +L
Sbjct: 1429 AVERNLETVEAERNELQQRLDATSN-DLKSQLRNSEDARAAVERNLETVEAERNELQQRL 1487

Query: 965  QEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEE 1024
                N++++   N E+        ++++++  + +  +  ++     N L + L+  ++ 
Sbjct: 1488 DATSNDLKSQLRNSEDAR----AAVERNLETVEAERNELQQRLDATSNDLKSQLRNSEDA 1543

Query: 1025 IIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQ-- 1082
              A+ + +   +     +    ++      ++L N E+    V + L   +    ELQ  
Sbjct: 1544 RAAVERNLETVEAERNELQQRLDATSNDLKSQLRNSEDARAAVERNLETVEAERNELQQR 1603

Query: 1083 --ILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXX 1140
                  +   Q++  ++ +   E N+   E     + ++   D  +N D           
Sbjct: 1604 LDATSNDLKSQLRNSEDARAAVERNLETVEAE--RNELQQRLDATSN-DLKSQLRNSEDA 1660

Query: 1141 XLKVQEEEEFIQ-ERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQL 1199
               V+   E ++ ER+ LQ+   +L+    +  +++   E     +  +    + + N+L
Sbjct: 1661 RAAVERNLETVEAERNELQQ---RLDATSNDLKSQLRNSEDARAAVERNLETVEAERNEL 1717

Query: 1200 KSKLEQLNTENDNLLSTVAELRSSISS-AVDQRGFEIAELWKQHLAQREADFQKTEHELR 1258
            + +L+   T ND      ++LR+S  + A  +R  E  E  +  L QR   F++    L 
Sbjct: 1718 QQRLDA--TSND----LKSQLRNSEDARAAVERNLETVEAERNELQQRLDVFERECAVLN 1771

Query: 1259 VQLSAFESK 1267
            ++LS    K
Sbjct: 1772 IRLSYLRRK 1780



 Score = 91.9 bits (218), Expect = 1e-16
 Identities = 190/1020 (18%), Positives = 429/1020 (42%), Gaps = 81/1020 (7%)

Query: 221  MQENFIAMEAEWKDEKQRLLKDIESKDVR--ISSLEEANKLLEAARFEISLEHSKLAQEL 278
            ++ N   +EAE  + +QRL  D  S D++  + + E+A   +E     +  E ++L Q L
Sbjct: 806  VERNLETVEAERNELQQRL--DATSNDLKSQLRNSEDARAAVERNLETVEAERNELQQRL 863

Query: 279  EQXXXXXXXXXXXXXXLAKQSIEPSCE----EKTEIEEK---GSLEIANMTELTKKIELL 331
            +                A+ ++E + E    E+ E++++    S ++ +    ++     
Sbjct: 864  DATSNDLKSQLRNSED-ARAAVERNLETVEAERNELQQRLDATSNDLKSQLRNSEDARAA 922

Query: 332  EHLNCQ-IRQTNKELENKLATMGTESKAVSSPSKKGSPLISR-----KSGRN-TASKMKS 384
               N + +     EL+ +L     + K+    S+     + R     ++ RN    ++ +
Sbjct: 923  VERNLETVEAERNELQQRLDATSNDLKSQLRNSEDARAAVERNLETVEAERNELQQRLDA 982

Query: 385  PWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDL-VDKEYVISEKDTXXXXXXXXXX 443
              + L S+  N +  +   +  +  +E     L + L      + S+             
Sbjct: 983  TSNDLKSQLRNSEDARAAVERNLETVEAERNELQQRLDATSNDLKSQLRNSEDARAAVER 1042

Query: 444  GKDTLIAQLQLEHQQHMEGPS--LIHVGTNTEDVN-EIAKVQEQLKQELND--EIKDVNV 498
              +T+ A+ + E QQ ++  S  L     N+ED    + +  E ++ E N+  +  D   
Sbjct: 1043 NLETVEAE-RNELQQRLDATSNDLKSQLRNSEDARAAVERNLETVEAERNELQQRLDATS 1101

Query: 499  KDLIEKLKSAEE--QITQLNDEIDAANKNMIKVKSNHKLK-LKQMQKTIDNFSKVSDSNK 555
             DL  +L+++E+     + N E   A +N ++ + +     LK   +  ++     + N 
Sbjct: 1102 NDLKSQLRNSEDARAAVERNLETVEAERNELQQRLDATSNDLKSQLRNSEDARAAVERNL 1161

Query: 556  EIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKA 615
            E V    E + L Q+   L+    +L+  L + +  R       + +    N  + RL A
Sbjct: 1162 ETVE--AERNELQQR---LDATSNDLKSQLRNSEDARAAVERNLETVEAERNELQQRLDA 1216

Query: 616  ISL-LESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSAS 674
             S  L+SQ  +       +++  + VE +  ++ Q + D   +++KS  L    DA +A 
Sbjct: 1217 TSNDLKSQLRNSEDARAAVERNLETVEAERNELQQ-RLDATSNDLKS-QLRNSEDARAAV 1274

Query: 675  KKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISE 734
            ++ L    E ++ ++ +L    + L+    D+ ++L+N       +   LE + AE+ +E
Sbjct: 1275 ERNL----ETVEAERNELQ---QRLDATSNDLKSQLRNSEDARAAVERNLETVEAER-NE 1326

Query: 735  LLAKINHEEQS-KIQTQFGIDAKIQ-ERDLYIENIESELSKYKSRICR----LEESIAVM 788
            L  +++      K Q +   DA+   ER+L  E +E+E ++ + R+      L+  +   
Sbjct: 1327 LQQRLDATSNDLKSQLRNSEDARAAVERNL--ETVEAERNELQQRLDATSNDLKSQLRNS 1384

Query: 789  EDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHEN 848
            ED R ++ER  + + +   E+ +         ++L ++L    D    VE+ L  +E E 
Sbjct: 1385 EDARAAVERNLETVEA---ERNELQQRLDATSNDLKSQLRNSEDARAAVERNLETVEAER 1441

Query: 849  KELQKK----NQILLEENQNLQISLSDMQQHYNAL-VEKANRTDLAESESTKYQTQLRDL 903
             ELQ++    +  L  + +N + + + ++++   +  E+       ++ S   ++QLR+ 
Sbjct: 1442 NELQQRLDATSNDLKSQLRNSEDARAAVERNLETVEAERNELQQRLDATSNDLKSQLRNS 1501

Query: 904  ESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYV----TQ 959
            E     +    +T+  ++ +  + L+   N  ++S +R+ +      E+N+E V     +
Sbjct: 1502 EDARAAVERNLETVEAERNELQQRLDATSN-DLKSQLRNSEDARAAVERNLETVEAERNE 1560

Query: 960  LEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLK 1019
            L+ +L    N++++   N E+        ++++++  + +  +  ++     N L + L+
Sbjct: 1561 LQQRLDATSNDLKSQLRNSEDAR----AAVERNLETVEAERNELQQRLDATSNDLKSQLR 1616

Query: 1020 QKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNE 1079
              ++   A+ + +   +     +    ++      ++L N E+    V + L   +    
Sbjct: 1617 NSEDARAAVERNLETVEAERNELQQRLDATSNDLKSQLRNSEDARAAVERNLETVEAERN 1676

Query: 1080 ELQ----ILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXX 1135
            ELQ        +   Q++  ++ +   E N+   E     + ++   D  +N D      
Sbjct: 1677 ELQQRLDATSNDLKSQLRNSEDARAAVERNLETVEAE--RNELQQRLDATSN-DLKSQLR 1733

Query: 1136 XXXXXXLKVQEEEEFIQ-ERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQE 1194
                    V+   E ++ ER+ LQ+   +L+   +EC    I+L  L  +L    VV +E
Sbjct: 1734 NSEDARAAVERNLETVEAERNELQQ---RLDVFERECAVLNIRLSYLRRKLLSGFVVGEE 1790



 Score = 83.0 bits (196), Expect = 6e-14
 Identities = 194/1042 (18%), Positives = 411/1042 (39%), Gaps = 87/1042 (8%)

Query: 590  SGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQ 649
            SG++I +      + + +LA +   A S +  Q+F+  + +++       V D LAD+++
Sbjct: 288  SGQVITTAGMSSRMNLVDLAGSERVAQSEVVGQQFNEARYINLSLTTLGRVIDMLADMAK 347

Query: 650  LQSDQVCS----EIKSVHLEEQIDALSASKKELAL-VIENLKLDKEQLYGTIKDLENDKE 704
             +S Q  +    E K  ++ +  D+L  + K   +  +    L+ E+   T++   +   
Sbjct: 348  NKSSQWSTPPYRESKLTYILK--DSLGGNSKTFMIATVSPSALNYEETLSTLR-YASRAR 404

Query: 705  DIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYI 764
            DI+N  +           +LE+   +   ++  K     +   +    ++A+ Q+R   +
Sbjct: 405  DIVNMTRVNEDPRARRIRELEEQMEQMRQDIKGKDPTYVRELEEKLVLLEAEAQKRAADL 464

Query: 765  ENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQE-KQKA-YSEYTIQ--E 820
              +E E  K    I R E+ +   E  R  L  KA +L   ++E K++A Y E   Q  +
Sbjct: 465  HALEKEREK---NIIR-EKMLYATEVEREELLIKATELERQVEESKRRAEYHEEMSQRLK 520

Query: 821  DELVNRLAVLMDHDRVVEKQLLEI-EHENKELQKKNQILLEENQNLQISLSDMQQHYNAL 879
            DE   R   L++  R    ++  I E ++ E+    Q L      L+      ++  + L
Sbjct: 521  DEYAQREQELLEKVRQHRAEIEGIRERKDAEMLSSQQQLSRVMSELEQERHSREEALHIL 580

Query: 880  VEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQ---KKKEIEDLEI---EFN 933
             E+  +   A   S +   +  +L+   + ++H  Q L+ +   +++ + DLE+   E N
Sbjct: 581  RERQEQLSAALCNSQQSSEKHTELQQQNEELSHRMQKLLEECEAQQRILSDLEVFRLERN 640

Query: 934  TQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYK----NNIENLNMNVE-ELNKMNLEL 988
               E A      L E   ++I+ +  L   +  +       +  +   VE +L K N   
Sbjct: 641  ELEEIAQFLDLKLEETEHRHIKTINHLLTTIGMHNLWQAELLTAVGTEVETQLTKCNQHH 700

Query: 989  IDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYES 1048
             D+    ++       EQ+         + K+ +++I+ L ++I  A+      +   + 
Sbjct: 701  FDQRAAMEKNHKLFQMEQH--------QMTKKLEQKILMLEKEIEEAK----KQLDTTKQ 748

Query: 1049 KLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQ----ILVREQDDQIKELKETKLTFEM 1104
              A  T K    E+    V + L   +   +ELQ        +   Q++  ++ +   E 
Sbjct: 749  SEAAITNKARQAEDARAAVERNLETVEAERDELQQRLDATSNDLKSQLRNSEDARAAVER 808

Query: 1105 NIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQ-ERSVLQEQSAK 1163
            N+   E     + ++   D  +N D              V+   E ++ ER+ LQ+   +
Sbjct: 809  NLETVEAE--RNELQQRLDATSN-DLKSQLRNSEDARAAVERNLETVEAERNELQQ---R 862

Query: 1164 LNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSS 1223
            L+    +  +++   E     +  +    + + N+L+ +L+   T ND      ++LR+S
Sbjct: 863  LDATSNDLKSQLRNSEDARAAVERNLETVEAERNELQQRLDA--TSND----LKSQLRNS 916

Query: 1224 ISS-AVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEE 1282
              + A  +R  E  E  +  L QR      T ++L+ QL   E     +  +++ + + E
Sbjct: 917  EDARAAVERNLETVEAERNELQQR---LDATSNDLKSQLRNSEDARAAVERNLE-TVEAE 972

Query: 1283 TNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXX 1342
             N++      TS      D +  LRN ++  A V   +E + +E  +             
Sbjct: 973  RNELQQRLDATS-----NDLKSQLRNSEDARAAVERNLETVEAERNE-------LQQRLD 1020

Query: 1343 XXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKV 1402
                     LR  ++  +   E+++  +  E  +L++                 DA A V
Sbjct: 1021 ATSNDLKSQLR-NSEDARAAVERNLETVEAERNELQQRLDATSNDLKSQLRNSEDARAAV 1079

Query: 1403 LELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAIL 1462
                  +E + +E+ Q+      T      +  N        E+ +E +    E+E   L
Sbjct: 1080 ERNLETVEAERNELQQR---LDATSNDLKSQLRNSEDARAAVERNLETV----EAERNEL 1132

Query: 1463 RLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEM 1522
            + ++   +N  ++  + SE  R  +   L     E   L +++   +  L+ ++  + + 
Sbjct: 1133 QQRLDATSNDLKSQLRNSEDARAAVERNLETVEAERNELQQRLDATSNDLKSQLRNSEDA 1192

Query: 1523 QTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLD--NTMNKEL 1580
            + A+E     + T+  E   LQ  + A+S+ ++  +  + D +   +  L+       EL
Sbjct: 1193 RAAVER---NLETVEAERNELQQRLDATSNDLKSQLRNSEDARAAVERNLETVEAERNEL 1249

Query: 1581 LDAVPRAELDLAMYMLHQRDVR 1602
               +     DL   + +  D R
Sbjct: 1250 QQRLDATSNDLKSQLRNSEDAR 1271



 Score = 82.2 bits (194), Expect = 1e-13
 Identities = 167/954 (17%), Positives = 380/954 (39%), Gaps = 75/954 (7%)

Query: 676  KELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAE-KISE 734
            +EL   +  L+ + ++    +  LE ++E      +N I+E M    ++E+     K +E
Sbjct: 444  RELEEKLVLLEAEAQKRAADLHALEKERE------KNIIREKMLYATEVEREELLIKATE 497

Query: 735  LLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYS 794
            L  ++   E+SK + ++  +   + +D Y +  +  L K +     +E      +    S
Sbjct: 498  LERQV---EESKRRAEYHEEMSQRLKDEYAQREQELLEKVRQHRAEIEGIRERKDAEMLS 554

Query: 795  LERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKK 854
             +++  ++ S L++++ +  E      E   +L+  + + +   ++  E++ +N+EL  +
Sbjct: 555  SQQQLSRVMSELEQERHSREEALHILRERQEQLSAALCNSQQSSEKHTELQQQNEELSHR 614

Query: 855  NQILLEENQNLQISLSDMQ---QHYNALVEKANRTDL-AESESTKYQTQLRDLESNLKRI 910
             Q LLEE +  Q  LSD++      N L E A   DL  E    ++   +  L + +   
Sbjct: 615  MQKLLEECEAQQRILSDLEVFRLERNELEEIAQFLDLKLEETEHRHIKTINHLLTTIGMH 674

Query: 911  THEHQTLIVQKKKEIEDLEIEFN----TQIESAIRDKKVLN-EKYE--KNIEY-VTQLEA 962
                  L+     E+E    + N     Q  +  ++ K+   E+++  K +E  +  LE 
Sbjct: 675  NLWQAELLTAVGTEVETQLTKCNQHHFDQRAAMEKNHKLFQMEQHQMTKKLEQKILMLEK 734

Query: 963  QLQEYKNNIENLNMNVEEL-NKMN-----LELIDKHVQKQQTQSPDYTEQYINEINKLNA 1016
            +++E K  ++    +   + NK          ++++++  + +  +  ++     N L +
Sbjct: 735  EIEEAKKQLDTTKQSEAAITNKARQAEDARAAVERNLETVEAERDELQQRLDATSNDLKS 794

Query: 1017 LLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQ 1076
             L+  ++   A+ + +   +     +    ++      ++L N E+    V + L   + 
Sbjct: 795  QLRNSEDARAAVERNLETVEAERNELQQRLDATSNDLKSQLRNSEDARAAVERNLETVEA 854

Query: 1077 HNEELQ----ILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXX 1132
               ELQ        +   Q++  ++ +   E N+   E     + ++   D  +N D   
Sbjct: 855  ERNELQQRLDATSNDLKSQLRNSEDARAAVERNLETVEAE--RNELQQRLDATSN-DLKS 911

Query: 1133 XXXXXXXXXLKVQEEEEFIQ-ERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVV 1191
                       V+   E ++ ER+ LQ+   +L+    +  +++   E     +  +   
Sbjct: 912  QLRNSEDARAAVERNLETVEAERNELQQ---RLDATSNDLKSQLRNSEDARAAVERNLET 968

Query: 1192 NQEQINQLKSKLEQLNTENDNLLSTVAELRSSISS-AVDQRGFEIAELWKQHLAQREADF 1250
             + + N+L+ +L+   T ND      ++LR+S  + A  +R  E  E  +  L QR    
Sbjct: 969  VEAERNELQQRLDA--TSND----LKSQLRNSEDARAAVERNLETVEAERNELQQR---L 1019

Query: 1251 QKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQ 1310
              T ++L+ QL   E     +  +++ + + E N++      TS      D +  LRN +
Sbjct: 1020 DATSNDLKSQLRNSEDARAAVERNLE-TVEAERNELQQRLDATS-----NDLKSQLRNSE 1073

Query: 1311 EKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNI 1370
            +  A V   +E + +E  +                      LR  ++  +   E+++  +
Sbjct: 1074 DARAAVERNLETVEAERNE-------LQQRLDATSNDLKSQLR-NSEDARAAVERNLETV 1125

Query: 1371 NEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQR 1430
              E  +L++                 DA A V      +E + +E+ Q+      T    
Sbjct: 1126 EAERNELQQRLDATSNDLKSQLRNSEDARAAVERNLETVEAERNELQQR---LDATSNDL 1182

Query: 1431 NDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEE 1490
              +  N        E+ +E +    E+E   L+ ++   +N  ++  + SE  R  +   
Sbjct: 1183 KSQLRNSEDARAAVERNLETV----EAERNELQQRLDATSNDLKSQLRNSEDARAAVERN 1238

Query: 1491 LNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRAS 1550
            L     E   L +++   +  L+ ++  + + + A+E     + T+  E   LQ  + A+
Sbjct: 1239 LETVEAERNELQQRLDATSNDLKSQLRNSEDARAAVER---NLETVEAERNELQQRLDAT 1295

Query: 1551 SSKIQKHVSFASDTKQGRDEQLD--NTMNKELLDAVPRAELDLAMYMLHQRDVR 1602
            S+ ++  +  + D +   +  L+       EL   +     DL   + +  D R
Sbjct: 1296 SNDLKSQLRNSEDARAAVERNLETVEAERNELQQRLDATSNDLKSQLRNSEDAR 1349


>UniRef50_Q4E572 Cluster: Antigenic protein, putative; n=2;
            Trypanosoma cruzi|Rep: Antigenic protein, putative -
            Trypanosoma cruzi
          Length = 2517

 Score =  123 bits (297), Expect = 4e-26
 Identities = 207/1069 (19%), Positives = 477/1069 (44%), Gaps = 74/1069 (6%)

Query: 295  LAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGT 354
            L + S++ +  E+T  E +       + +L + +E L++    +     + + ++    T
Sbjct: 699  LLQASLDEATSERTFAENR-------IADLQRTVENLQNQLNVLENAETDYKTEMYKQTT 751

Query: 355  ESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVI 414
            + + + + +K  SP  S    R    K+     + S+      T  +    E   LE   
Sbjct: 752  KKEPLEARAKNDSP--SEDFLRTQIGKLNPVEKETSAAKQLTGTKNQEKAGEQYDLEKPN 809

Query: 415  QSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTED 474
                     K YV +   T             +  A+ QL+  + +E  S    G   ++
Sbjct: 810  TPYINYKTTKNYVFTSSGTKQEKSTSRTKNI-SCTAEPQLKQNKKVEDTSAFKKGREEDN 868

Query: 475  VNEIAKVQEQL-----KQELNDEIKDVNVKDL-IEKLKSAEEQITQLNDEIDAANKNMIK 528
            V +    Q+ L     KQ+  +E++    K+  I+K ++ ++ +        + ++N  K
Sbjct: 869  VKKSDNKQQSLQEMFVKQQEEEELQQFQQKNKHIQKTENEQQHVKSKIIPTTSKSENQ-K 927

Query: 529  VKSNHKLKLKQMQKTIDNFS---KVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHL 585
             K+  + KL+++ K  +  S   ++++  K+     +++   ++   E  ++  + + H 
Sbjct: 928  EKAIPQNKLQKVIKKTEKHSITRQITEETKQNTIPIKKVPAQNKDFHENTKQNSDERKHT 987

Query: 586  VDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLA 645
            +   +G   +++  +  ++     E +L A   L+ Q   L  +L    ++    E+KL 
Sbjct: 988  MKTMAGLQRQNEELQSQLKESRRGEEKLDA---LQRQNEQLQSQL----KESCRGEEKL- 1039

Query: 646  DISQLQSDQVCSEIK-SVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKE 704
            D  Q Q++++ S++K S   EE++DAL    +EL   ++  +  +E+L      L+   E
Sbjct: 1040 DALQRQNEELQSQLKESRRGEEKLDALQRQNEELQSQLKESRRGEEKLDA----LQRQNE 1095

Query: 705  DIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQ-SKIQTQFG-IDAKIQERDL 762
             + ++L+   +   +  D L++ + +  S+L      EE+   +Q Q   + ++++E   
Sbjct: 1096 QLQSQLKES-RRGEEKLDALQRQNEQLQSQLRESRRGEEKLDALQRQNEELQSQLKESRR 1154

Query: 763  YIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTI---Q 819
              E +++   + +    +L+ES    E++  +L+R+ +QL S L+E ++   +      Q
Sbjct: 1155 GEEKLDALQRQNEQLQSQLKESRRG-EEKLDALQRQNEQLQSQLKESRRGEEKLDALQRQ 1213

Query: 820  EDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNAL 879
             +EL ++L       R  E++L  ++ +N+ELQ +    L+E++  +  L  +Q+    L
Sbjct: 1214 NEELQSQLK----ESRRGEEKLDALQRQNEELQSQ----LKESRRGEEKLDALQRQNEEL 1265

Query: 880  VEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTL-IVQKKKEIEDLEIEFNTQIES 938
              +   +   E +    Q Q   L+S LK      + L  +Q++ E    +++ + + E 
Sbjct: 1266 QSQLKESRRGEEKLDALQRQNEQLQSQLKESRRGEEKLDALQRQNEELQSQLKESRRGEE 1325

Query: 939  AIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNK--MNLELIDKHVQKQ 996
             +   +  NE+ +  ++   + E +L   +   E L   ++E  +    L+ + +  ++ 
Sbjct: 1326 KLDALQRQNEELQSQLKESRRGEEKLDALQRQNEELQSQLKESRRGEEKLDALQRQNEEL 1385

Query: 997  QTQSPDYT--EQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDY-ESKLAQF 1053
            Q+Q  +    E+ ++ + + N  L+ + +E     +K++  Q     + S   ES+  + 
Sbjct: 1386 QSQLKESRRGEEKLDALQRQNEQLQSQLKESRRGEEKLDALQRQNEELQSQLKESRRGE- 1444

Query: 1054 TTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFE-MNIPKTEGM 1112
              KL+ ++ + +++  QL +S++  E+L  L R+ +    +LKE++   E ++  + +  
Sbjct: 1445 -EKLDALQRQNEQLQSQLKESRRGEEKLDALQRQNEQLQSQLKESRRGEEKLDALQRQNE 1503

Query: 1113 IISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECY 1172
             + S ++        +D            LK     E  ++   LQ Q+ +L ++L+E  
Sbjct: 1504 ELQSQLKESRRGEEKLDALQRQNEELRSQLKESRRGE--EKLDALQRQNEQLQSQLKESR 1561

Query: 1173 TKIIQLETLNTELTGHDVVNQ-EQINQLKSKLEQLNTENDNLLSTVAELRSSISS--AVD 1229
                +L+ L  +     + +Q ++  + + KL+ L  +N+ L S + E R       A+ 
Sbjct: 1562 RGEEKLDALQRQ--NEQLQSQLKESRRGEEKLDALQRQNEELQSQLKESRHGEEKLDALQ 1619

Query: 1230 QRGFEI-AELWKQHLAQREAD-FQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIV 1287
            ++  E+ ++L +    + + D  Q+   EL+ QL     + E+ LD++Q   +E  +++ 
Sbjct: 1620 RQNEELRSQLKESRRGEEKLDALQRQNEELQSQLKE-SRRGEEKLDALQRQNEELQSQLK 1678

Query: 1288 TM----EQVTSLQNK---LQDKEEHLRNLQEKYADVINQIEILRSEIED 1329
                  E++ +LQ +   LQ + +  R  +EK   +  Q E LRS++ +
Sbjct: 1679 ESRRGEEKLDALQRQNEELQSQLKESRRGEEKLDALQRQNEELRSQLRE 1727



 Score =  111 bits (267), Expect = 2e-22
 Identities = 171/809 (21%), Positives = 365/809 (45%), Gaps = 69/809 (8%)

Query: 480  KVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQ 539
            ++Q QLK+    E K   ++   E+L+S  ++  +  +++DA  +   +++S    +LK+
Sbjct: 1144 ELQSQLKESRRGEEKLDALQRQNEQLQSQLKESRRGEEKLDALQRQNEQLQS----QLKE 1199

Query: 540  MQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVY 599
             ++  +    +   N+E+    +E     +K+  L+ +   LQ  L +   G      + 
Sbjct: 1200 SRRGEEKLDALQRQNEELQSQLKESRRGEEKLDALQRQNEELQSQLKESRRGEEKLDALQ 1259

Query: 600  KKMIEMEN-LAETRL--KAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVC 656
            ++  E+++ L E+R   + +  L+ Q   L  +L    ++    E+KL D  Q Q++++ 
Sbjct: 1260 RQNEELQSQLKESRRGEEKLDALQRQNEQLQSQL----KESRRGEEKL-DALQRQNEELQ 1314

Query: 657  SEIK-SVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQ 715
            S++K S   EE++DAL    +EL   ++  +  +E+L      L+   E++ ++L+   +
Sbjct: 1315 SQLKESRRGEEKLDALQRQNEELQSQLKESRRGEEKLDA----LQRQNEELQSQLKES-R 1369

Query: 716  ENMDLTDKLEKMSAEKISELLAKINHEEQ-SKIQTQFG-IDAKIQERDLYIENIESELSK 773
               +  D L++ + E  S+L      EE+   +Q Q   + ++++E     E +++   +
Sbjct: 1370 RGEEKLDALQRQNEELQSQLKESRRGEEKLDALQRQNEQLQSQLKESRRGEEKLDALQRQ 1429

Query: 774  YKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDH 833
             +    +L+ES    E++  +L+R+ +QL S L+E ++   +    + +   +L   +  
Sbjct: 1430 NEELQSQLKESRRG-EEKLDALQRQNEQLQSQLKESRRGEEKLDALQRQN-EQLQSQLKE 1487

Query: 834  DRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESES 893
             R  E++L  ++ +N+ELQ +    L+E++  +  L  +Q+    L  +   +   E + 
Sbjct: 1488 SRRGEEKLDALQRQNEELQSQ----LKESRRGEEKLDALQRQNEELRSQLKESRRGEEKL 1543

Query: 894  TKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKN 953
               Q Q   L+S LK      + L   +++         N Q++S +++ +   EK +  
Sbjct: 1544 DALQRQNEQLQSQLKESRRGEEKLDALQRQ---------NEQLQSQLKESRRGEEKLDAL 1594

Query: 954  IEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINK 1013
                 +L++QL+E ++  E L    + L + N EL      + Q +     E+ ++ + +
Sbjct: 1595 QRQNEELQSQLKESRHGEEKL----DALQRQNEEL------RSQLKESRRGEEKLDALQR 1644

Query: 1014 LNALLKQKDEEIIALNQKINNAQVSYMSMVSDY-ESKLAQFTTKLENMEEEMQRVSKQLL 1072
             N  L+ + +E     +K++  Q     + S   ES+  +   KL+ ++ + + +  QL 
Sbjct: 1645 QNEELQSQLKESRRGEEKLDALQRQNEELQSQLKESRRGE--EKLDALQRQNEELQSQLK 1702

Query: 1073 DSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXX 1132
            +S++  E+L  L R+ ++   +L+ET    E    K E    S   E  +      D   
Sbjct: 1703 ESRRGEEKLDALQRQNEELRSQLRETCRGPE----KLE----SEEEEEAAHQLVAEDESE 1754

Query: 1133 XXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVN 1192
                         E  E  ++   L+ Q  KL  +L+E      +L+ L      H+   
Sbjct: 1755 AMTAALGEASGKPEAAELQRQLDALRRQKEKLRLQLREARRGQEKLDILRR----HNEDL 1810

Query: 1193 QEQINQLK---SKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREAD 1249
            Q ++N  +    KL+ L   N+ L S + E R +  +  D R        +Q   Q E D
Sbjct: 1811 QSRLNDARRGQEKLDALQRHNEELQSQLCEARRAEEALEDAR-----RQTRQSQRQVE-D 1864

Query: 1250 FQKTEHELRVQLSAFESKYEQLLDSVQSS 1278
             +++E  LR    A  ++ E L+  ++++
Sbjct: 1865 LRRSEKRLREACEATRAREEALMQKLRAA 1893



 Score = 83.8 bits (198), Expect = 4e-14
 Identities = 152/824 (18%), Positives = 347/824 (42%), Gaps = 42/824 (5%)

Query: 305  EEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSK 364
            EEK +  ++ + E+ +  + +++ E  E L+   RQ N+EL+++L       + + +  +
Sbjct: 1228 EEKLDALQRQNEELQSQLKESRRGE--EKLDALQRQ-NEELQSQLKESRRGEEKLDALQR 1284

Query: 365  KGSPLISR-KSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVD 423
            +   L S+ K  R    K+ +   Q + E  +Q  + +  + ++  L+   + L   L +
Sbjct: 1285 QNEQLQSQLKESRRGEEKLDALQRQ-NEELQSQLKESRRGEEKLDALQRQNEELQSQLKE 1343

Query: 424  KEYVISEKDTXXXXXXXXXXG-KDTLIAQLQLE--HQQHMEGPSLIHVGTNTED-VNEIA 479
                  + D             K++   + +L+   +Q+ E  S +      E+ ++ + 
Sbjct: 1344 SRRGEEKLDALQRQNEELQSQLKESRRGEEKLDALQRQNEELQSQLKESRRGEEKLDALQ 1403

Query: 480  KVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLK--L 537
            +  EQL+ +L +  +     D +++    EE  +QL +      K     + N +L+  L
Sbjct: 1404 RQNEQLQSQLKESRRGEEKLDALQRQN--EELQSQLKESRRGEEKLDALQRQNEQLQSQL 1461

Query: 538  KQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESD 597
            K+ ++  +    +   N+++    +E     +K+  L+ +   LQ  L +   G      
Sbjct: 1462 KESRRGEEKLDALQRQNEQLQSQLKESRRGEEKLDALQRQNEELQSQLKESRRGEEKLDA 1521

Query: 598  VYKKMIEMEN-LAETRL--KAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQ 654
            + ++  E+ + L E+R   + +  L+ Q   L  +L    ++    E+KL D  Q Q++Q
Sbjct: 1522 LQRQNEELRSQLKESRRGEEKLDALQRQNEQLQSQL----KESRRGEEKL-DALQRQNEQ 1576

Query: 655  VCSEIK-SVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMN----- 708
            + S++K S   EE++DAL    +EL   ++  +  +E+L    +  E  +  +       
Sbjct: 1577 LQSQLKESRRGEEKLDALQRQNEELQSQLKESRHGEEKLDALQRQNEELRSQLKESRRGE 1636

Query: 709  -KLQNYIQENMDLTDKL-EKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIEN 766
             KL    ++N +L  +L E    E+  + L + N E QS+++     + K+       E 
Sbjct: 1637 EKLDALQRQNEELQSQLKESRRGEEKLDALQRQNEELQSQLKESRRGEEKLDALQRQNEE 1696

Query: 767  IESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNR 826
            ++S+L + +    +L+      E+ R  L            E+++  +   + EDE    
Sbjct: 1697 LQSQLKESRRGEEKLDALQRQNEELRSQLRETCRGPEKLESEEEEEAAHQLVAEDESEAM 1756

Query: 827  LAVLMDHDRVVEKQLLEIEHENKELQK-KNQILLEENQNLQISLSDMQQHYNALVEKANR 885
             A L +     E   L+ + +    QK K ++ L E +  Q  L  +++H   L  + N 
Sbjct: 1757 TAALGEASGKPEAAELQRQLDALRRQKEKLRLQLREARRGQEKLDILRRHNEDLQSRLND 1816

Query: 886  TDLAESESTKYQTQLRDLESNLKRITHEHQTL------IVQKKKEIEDLEIEFNTQIESA 939
                + +    Q    +L+S L       + L        Q ++++EDL      ++  A
Sbjct: 1817 ARRGQEKLDALQRHNEELQSQLCEARRAEEALEDARRQTRQSQRQVEDLR-RSEKRLREA 1875

Query: 940  IRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIEN-----LNMNVEELNKMNLELIDKHVQ 994
                +   E   + +       A  +++++ ++      +N    E  +    L +    
Sbjct: 1876 CEATRAREEALMQKLRAAENAIAVARKHEDAVKQKARGIINAVKTEYQRQPFVLPEPQET 1935

Query: 995  KQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFT 1054
            +Q  ++ D     ++E       L+ ++E    L  +  +  ++     +  + + A+  
Sbjct: 1936 EQLQRANDSPRAPLDEPPLTKEGLESEEEAAHQLMAEDESEAMTAALGEASGKPEAAELQ 1995

Query: 1055 TKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKET 1098
             +L+ +  + +++  QL ++++  E+L IL R+ ++   +L+ET
Sbjct: 1996 RQLDALRRQKEKLRLQLREARRGQEKLDILQRQNEELRSQLRET 2039



 Score = 80.2 bits (189), Expect = 4e-13
 Identities = 155/839 (18%), Positives = 361/839 (43%), Gaps = 53/839 (6%)

Query: 780  RLEESIAVMEDRRYSLERKADQLGSYLQEK-QKAYSEYTIQEDELVNRLAVLMDHDRVVE 838
            ++E++ A  + R     +K+D     LQE   K   E  +Q+ +  N+     ++++   
Sbjct: 853  KVEDTSAFKKGREEDNVKKSDNKQQSLQEMFVKQQEEEELQQFQQKNKHIQKTENEQQHV 912

Query: 839  KQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQT 898
            K  +       E QK+  I   + Q + I  ++       + E+  +  +      K   
Sbjct: 913  KSKIIPTTSKSENQKEKAIPQNKLQKV-IKKTEKHSITRQITEETKQNTIPIK---KVPA 968

Query: 899  QLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVT 958
            Q +D   N K+ + E +  +    K +  L+ + N +++S +++ +   EK +       
Sbjct: 969  QNKDFHENTKQNSDERKHTM----KTMAGLQRQ-NEELQSQLKESRRGEEKLDALQRQNE 1023

Query: 959  QLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALL 1018
            QL++QL+E     E L    + L + N EL      + Q +     E+ ++ + + N  L
Sbjct: 1024 QLQSQLKESCRGEEKL----DALQRQNEEL------QSQLKESRRGEEKLDALQRQNEEL 1073

Query: 1019 KQKDEEIIALNQKINNAQVSYMSMVSDY-ESKLAQFTTKLENMEEEMQRVSKQLLDSKQH 1077
            + + +E     +K++  Q     + S   ES+  +   KL+ ++ + +++  QL +S++ 
Sbjct: 1074 QSQLKESRRGEEKLDALQRQNEQLQSQLKESRRGE--EKLDALQRQNEQLQSQLRESRRG 1131

Query: 1078 NEELQILVREQDDQIKELKETKLTFE-MNIPKTEGMIISSTIEPMSDDANNVDXXXXXXX 1136
             E+L  L R+ ++   +LKE++   E ++  + +   + S ++        +D       
Sbjct: 1132 EEKLDALQRQNEELQSQLKESRRGEEKLDALQRQNEQLQSQLKESRRGEEKLDALQRQNE 1191

Query: 1137 XXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQ-EQ 1195
                 LK     E  ++   LQ Q+ +L ++L+E      +L+ L  +    ++ +Q ++
Sbjct: 1192 QLQSQLKESRRGE--EKLDALQRQNEELQSQLKESRRGEEKLDALQRQ--NEELQSQLKE 1247

Query: 1196 INQLKSKLEQLNTENDNLLSTVAELRSSIS--SAVDQRGFEI-AELWKQHLAQREAD-FQ 1251
              + + KL+ L  +N+ L S + E R       A+ ++  ++ ++L +    + + D  Q
Sbjct: 1248 SRRGEEKLDALQRQNEELQSQLKESRRGEEKLDALQRQNEQLQSQLKESRRGEEKLDALQ 1307

Query: 1252 KTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTM----EQVTSLQ---NKLQDKEE 1304
            +   EL+ QL     + E+ LD++Q   +E  +++       E++ +LQ    +LQ + +
Sbjct: 1308 RQNEELQSQLKE-SRRGEEKLDALQRQNEELQSQLKESRRGEEKLDALQRQNEELQSQLK 1366

Query: 1305 HLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQE 1364
              R  +EK   +  Q E L+S++++ +                    L+   +  +++  
Sbjct: 1367 ESRRGEEKLDALQRQNEELQSQLKESRRG-EEKLDALQRQNEQLQSQLKESRRGEEKL-- 1423

Query: 1365 QSILNINEE-NAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEY 1423
             ++   NEE  +QLK+S             R N+     L+ + + E K   + ++  + 
Sbjct: 1424 DALQRQNEELQSQLKES--RRGEEKLDALQRQNEQLQSQLKESRRGEEKLDALQRQNEQL 1481

Query: 1424 TITL--TQRNDE-FENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKES 1480
               L  ++R +E  + +++Q  E + ++++    +E   A+ R      +   E+ + E 
Sbjct: 1482 QSQLKESRRGEEKLDALQRQNEELQSQLKESRRGEEKLDALQRQNEELRSQLKESRRGE- 1540

Query: 1481 EIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEI 1540
              E++  ++  N ++   +  +++  E   AL+ +  +           E ++  L  + 
Sbjct: 1541 --EKLDALQRQNEQLQSQLKESRRGEEKLDALQRQNEQLQSQLKESRRGEEKLDALQRQN 1598

Query: 1541 TNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDLAMYMLHQR 1599
              LQ+ ++ S    +K  +     ++ R +  ++   +E LDA+ R   +L   +   R
Sbjct: 1599 EELQSQLKESRHGEEKLDALQRQNEELRSQLKESRRGEEKLDALQRQNEELQSQLKESR 1657



 Score = 58.8 bits (136), Expect = 1e-06
 Identities = 158/857 (18%), Positives = 356/857 (41%), Gaps = 71/857 (8%)

Query: 754  DAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAY 813
            D K+++     E++++ L   +  + +++  +A + D+    ER+  +    +   Q + 
Sbjct: 645  DRKMEDLIRRNEDLQALLKDSRRSMEKMQSVVATITDKNNEWEREITERQRQIVLLQASL 704

Query: 814  SEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQ 873
             E T +     NR+A L      ++ QL  +  EN E   K ++  +  +   +   + +
Sbjct: 705  DEATSERTFAENRIADLQRTVENLQNQLNVL--ENAETDYKTEMYKQTTKKEPL---EAR 759

Query: 874  QHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFN 933
               ++  E   RT + +    + +T      S  K++T    T   +K  E  DLE + N
Sbjct: 760  AKNDSPSEDFLRTQIGKLNPVEKET------SAAKQLT---GTKNQEKAGEQYDLE-KPN 809

Query: 934  TQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHV 993
            T           +N K  KN  + T    + ++  +  +N++   E   K N ++ D   
Sbjct: 810  T---------PYINYKTTKNYVF-TSSGTKQEKSTSRTKNISCTAEPQLKQNKKVEDTSA 859

Query: 994  QKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQF 1053
             K+  +  +  +    + +     +KQ++EE +   Q+ N       +     +SK+   
Sbjct: 860  FKKGREEDNVKKSDNKQQSLQEMFVKQQEEEELQQFQQKNKHIQKTENEQQHVKSKIIPT 919

Query: 1054 TTKLENMEEE---MQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTE 1110
            T+K EN +E+     ++ K +  +++H+   QI         +E K+  +  +  +P  +
Sbjct: 920  TSKSENQKEKAIPQNKLQKVIKKTEKHSITRQI--------TEETKQNTIPIK-KVP-AQ 969

Query: 1111 GMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSV--LQEQSAKLNTEL 1168
                    +  SD+  +              L+ Q +E    E  +  LQ Q+ +L ++L
Sbjct: 970  NKDFHENTKQNSDERKHTMKTMAGLQRQNEELQSQLKESRRGEEKLDALQRQNEQLQSQL 1029

Query: 1169 QECYTKIIQLETLNTELTGHDVVNQ-EQINQLKSKLEQLNTENDNLLSTVAELRSSISSA 1227
            +E      +L+ L  +    ++ +Q ++  + + KL+ L  +N+ L S + E R      
Sbjct: 1030 KESCRGEEKLDALQRQ--NEELQSQLKESRRGEEKLDALQRQNEELQSQLKESR------ 1081

Query: 1228 VDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIV 1287
               RG E  +  ++   Q ++  +++      +L A + + EQL   ++ S + E     
Sbjct: 1082 ---RGEEKLDALQRQNEQLQSQLKESRRG-EEKLDALQRQNEQLQSQLRESRRGEEKLDA 1137

Query: 1288 TMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXX 1347
               Q   LQ++L++     R  +EK   +  Q E L+S++++ +                
Sbjct: 1138 LQRQNEELQSQLKES----RRGEEKLDALQRQNEQLQSQLKESRRG-EEKLDALQRQNEQ 1192

Query: 1348 XXXDLRTENQSYKQMQEQSILNINEE-NAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELT 1406
                L+   +  +++   ++   NEE  +QLK+S             R N+     L+ +
Sbjct: 1193 LQSQLKESRRGEEKL--DALQRQNEELQSQLKES--RRGEEKLDALQRQNEELQSQLKES 1248

Query: 1407 HQLELKDSEIYQKTHEYTITL--TQRNDE-FENVRQQLVEYEKRIEDLTYEKESELAILR 1463
             + E K   + ++  E    L  ++R +E  + +++Q  + + ++++    +E   A+ R
Sbjct: 1249 RRGEEKLDALQRQNEELQSQLKESRRGEEKLDALQRQNEQLQSQLKESRRGEEKLDALQR 1308

Query: 1464 LKMHENANHYETMQKESEIERV-KLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEM 1522
                  +   E+ + E +++ + +  EEL  ++ ES    +++  L +  EE  ++  E 
Sbjct: 1309 QNEELQSQLKESRRGEEKLDALQRQNEELQSQLKESRRGEEKLDALQRQNEELQSQLKES 1368

Query: 1523 QTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLD 1582
            +      E ++  L  +   LQ+ ++ S    +K  +     +Q + +  ++   +E LD
Sbjct: 1369 RRG----EEKLDALQRQNEELQSQLKESRRGEEKLDALQRQNEQLQSQLKESRRGEEKLD 1424

Query: 1583 AVPRAELDLAMYMLHQR 1599
            A+ R   +L   +   R
Sbjct: 1425 ALQRQNEELQSQLKESR 1441


>UniRef50_A3LZ88 Cluster: Myosin-1; n=1; Pichia stipitis|Rep: Myosin-1
            - Pichia stipitis (Yeast)
          Length = 1874

 Score =  123 bits (297), Expect = 4e-26
 Identities = 172/872 (19%), Positives = 355/872 (40%), Gaps = 71/872 (8%)

Query: 781  LEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQ-------------EDELVNRL 827
            LEES+ V+ED   S   K   + S L+E +K+ S    +             EDE++   
Sbjct: 819  LEESVKVLEDAEMS--EKVKDISSKLEEAEKSKSNLEDENSKLKEQEQINKLEDEIITTT 876

Query: 828  AVLMDHDRVVEKQLLE---IEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKAN 884
             ++ D D  +EK   E   I    +E + K   + +EN  L      +        E +N
Sbjct: 877  NLVKDKDLKLEKAKSEEAKISSRIREFESKINQMKQENNKLSEEKKLLDSKLKESSENSN 936

Query: 885  RTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIE---FNTQIESAIR 941
            R     S  TK +   +   ++L+ +  +H+   V+++K IEDL+ E     +  ES + 
Sbjct: 937  RNIADLSSLTKERDDFKSKLADLELVVKKHKLEKVEREKHIEDLKKEHASLKSSSESKVE 996

Query: 942  DKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSP 1001
            D K L+ K E+ I   + +  + +   + ++ L  ++   ++ +LE  D+ +Q+  ++  
Sbjct: 997  DMKQLSRKLEEEISKNSLILPKHESLLDEVKKLK-DLLSKSESDLESKDREIQETMSKQK 1055

Query: 1002 DYTEQYINEINKLNALLKQKDE----EIIALNQKINNAQVSYMSMVSDYESKLAQFTTKL 1057
             + E+ I  +   N  LK++ E    EI   N ++   Q+  ++ +S  E +  Q  T +
Sbjct: 1056 LFEEENIKVLEGTNKALKKEVESHKDEIAQKNAQVEKLQIQ-VAKLSSLEKETEQLNTLV 1114

Query: 1058 ENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISST 1117
             N   E+Q + +QL DS + N+ L ++V +        +  K  +   I      I+S  
Sbjct: 1115 TNQSLEIQNLQEQLSDSVRENKSLSVVVEKLKVDYDAARIAKEEYSDKI-----FILSKK 1169

Query: 1118 IEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQ 1177
            +  + ++A   +            +     EEF   +  L E +A L  E  E    + +
Sbjct: 1170 LSELEEEAREKEIEKENQPPDPAFV-----EEFAHIKLKLNENTAALRKEKFENKKLVEE 1224

Query: 1178 LETLNTELTGHDVVNQEQI--NQLKSKLEQLNTENDNLLSTVAELRSSISSA--VDQRGF 1233
            L  L          ++  I  N+L+S+ E L++ ++ + S   +L+  +S++   +    
Sbjct: 1225 LSMLRDRFHNESQQDRSPIKQNELRSRTETLDSLHEEINSLKLQLQQEMSNSQRAENYAI 1284

Query: 1234 EIAELWKQHLAQRE----ADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTM 1289
            +I +   +  A R      D++K   E + ++S  E K+E+ + S   S  E +  I   
Sbjct: 1285 DIQKKLNRLSATRGINSWTDYEKKFRESQRRVSELEGKFEEFI-SADESFSEASRSISKS 1343

Query: 1290 EQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAF----XXXXXXXXXXX 1345
            +    +   +    +      + Y D+   +   R E+   K                  
Sbjct: 1344 DSFGRISFSMTSNSD----FAQIYQDITKTLRTTREELTTSKSEILRLKSLLRESEDELY 1399

Query: 1346 XXXXXDLRTENQSYKQMQEQSIL---NINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKV 1402
                 + +T    Y+    Q  +    +  +N+ L  +             ++  AEA V
Sbjct: 1400 SAKTANFKTSISDYEDKLAQLTVRHDTLRTKNSDLASNLELYKRRSEEYYDKLELAEAAV 1459

Query: 1403 LELTHQLELKDSEIYQKTHEYTITLTQRNDE---FENVRQQLVEYEKRIEDLTY---EKE 1456
                   E   +++ +  ++  +   +        + +R    + E+ I+D  +   ++E
Sbjct: 1460 QISKRHEESALNDLNETKNQLKLAKEEARTSQIMIKEIRTNNSKLEETIQDKNFAMKQQE 1519

Query: 1457 SELAILRLKMHENANHYETMQKESEI--ERVKLIEELNVKITESVSLNKQVAELNKALEE 1514
            +++  L+ K++ +  +YE  +K  +   E + L +EL  K     SL K   +L   LE+
Sbjct: 1520 AKIKELKEKIYYHKKNYENKEKTDKYREEIITLNKELAFKTDTENSLIKDSKKLQLDLED 1579

Query: 1515 --EVAKTNEMQTALENQEIEIV-TLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQ 1571
              +  KT E   AL+ + + ++ T  D ++N    +  +     + +   +       E 
Sbjct: 1580 LTKEKKTLEEDYALKIEHVNVLETRVDLLSNKSRQLENAQEINDRKIGNLNKQVSSLREL 1639

Query: 1572 LDNTMNK--ELLDAVPRAELDLAMYMLHQRDV 1601
            +++  N+  ELL+   + E D    + H+ D+
Sbjct: 1640 VESVTNQRDELLETKAKLE-DQLSELTHKLDL 1670



 Score =  119 bits (287), Expect = 6e-25
 Identities = 202/1022 (19%), Positives = 429/1022 (41%), Gaps = 81/1022 (7%)

Query: 556  EIVRLTEELHHLSQKVAELEEEKGNLQ---LHLVDYDSGRMIESDVYK-------KMIEM 605
            E   ++E++  +S K+ E E+ K NL+     L + +    +E ++         K +++
Sbjct: 827  EDAEMSEKVKDISSKLEEAEKSKSNLEDENSKLKEQEQINKLEDEIITTTNLVKDKDLKL 886

Query: 606  ENLAETRLKAISLL---ESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSV 662
            E       K  S +   ES+   + QE + L ++   ++ KL + S+  S++  +++ S 
Sbjct: 887  EKAKSEEAKISSRIREFESKINQMKQENNKLSEEKKLLDSKLKESSE-NSNRNIADLSS- 944

Query: 663  HLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTD 722
             L ++ D   +   +L LV++  KL+K +    I+DL+ +   + +  ++ +++   L+ 
Sbjct: 945  -LTKERDDFKSKLADLELVVKKHKLEKVEREKHIEDLKKEHASLKSSSESKVEDMKQLSR 1003

Query: 723  KLEKMSAEKISELLAKINHEE-QSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRL 781
            KLE+    K S +L K  HE    +++    + +K  E DL  ++ E + +  K ++   
Sbjct: 1004 KLEE-EISKNSLILPK--HESLLDEVKKLKDLLSK-SESDLESKDREIQETMSKQKLFE- 1058

Query: 782  EESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQL 841
            EE+I V+E    +L+++ +     + +K     +  IQ  +L +        + +V  Q 
Sbjct: 1059 EENIKVLEGTNKALKKEVESHKDEIAQKNAQVEKLQIQVAKLSSLEKETEQLNTLVTNQS 1118

Query: 842  LEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNAL-VEKANRTDLAESESTKYQTQL 900
            LEI++    LQ++    + EN++L + +  ++  Y+A  + K   +D     S K  ++L
Sbjct: 1119 LEIQN----LQEQLSDSVRENKSLSVVVEKLKVDYDAARIAKEEYSDKIFILSKKL-SEL 1173

Query: 901  RDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYV-TQ 959
             + E+  K I  E+Q       +E   ++++ N +  +A+R +K  N+K  + +  +  +
Sbjct: 1174 EE-EAREKEIEKENQPPDPAFVEEFAHIKLKLN-ENTAALRKEKFENKKLVEELSMLRDR 1231

Query: 960  LEAQLQEYKNNIE--NLNMNVEELNKMNLELIDKHVQKQQTQS-PDYTEQYINEI-NKLN 1015
               + Q+ ++ I+   L    E L+ ++ E+    +Q QQ  S     E Y  +I  KLN
Sbjct: 1232 FHNESQQDRSPIKQNELRSRTETLDSLHEEINSLKLQLQQEMSNSQRAENYAIDIQKKLN 1291

Query: 1016 ALLKQKD-EEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSK----- 1069
             L   +         +K   +Q      VS+ E K  +F +  E+  E  + +SK     
Sbjct: 1292 RLSATRGINSWTDYEKKFRESQ----RRVSELEGKFEEFISADESFSEASRSISKSDSFG 1347

Query: 1070 QLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVD 1129
            ++  S   N +   + ++    ++  +E   T +  I + + ++  S  E  S    N  
Sbjct: 1348 RISFSMTSNSDFAQIYQDITKTLRTTREELTTSKSEILRLKSLLRESEDELYSAKTANFK 1407

Query: 1130 XXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHD 1189
                        L V+  +    + S L           +E Y K+   E        H+
Sbjct: 1408 TSISDYEDKLAQLTVR-HDTLRTKNSDLASNLELYKRRSEEYYDKLELAEAAVQISKRHE 1466

Query: 1190 VVNQEQINQLKSKLEQLNTENDNLLSTVAELR---SSISSAVDQRGFEIAEL-WKQHLAQ 1245
                  +N+ K++L+    E       + E+R   S +   +  + F + +   K    +
Sbjct: 1467 ESALNDLNETKNQLKLAKEEARTSQIMIKEIRTNNSKLEETIQDKNFAMKQQEAKIKELK 1526

Query: 1246 READFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEH 1305
             +  + K  +E + +   +  +   L   +   T  E + I   +    LQ  L+D  + 
Sbjct: 1527 EKIYYHKKNYENKEKTDKYREEIITLNKELAFKTDTENSLI---KDSKKLQLDLEDLTKE 1583

Query: 1306 LRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQ 1365
             + L+E YA  I  + +L + ++                      +   + ++ +++ ++
Sbjct: 1584 KKTLEEDYALKIEHVNVLETRVD-------------------LLSNKSRQLENAQEINDR 1624

Query: 1366 SILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTI 1425
             I N+N++ + L++                   E ++ ELTH+L+L ++E+ Q   +  I
Sbjct: 1625 KIGNLNKQVSSLRELVESVTNQRDELLETKAKLEDQLSELTHKLDLSEAELAQTNKDMNI 1684

Query: 1426 TLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILR--LKMHENANHYETMQKESEIE 1483
              T      EN RQ+  E +  +        SE+   +   K H  ++      K+   E
Sbjct: 1685 LRT----HLENQRQESSEIKSELSQSRSSISSEMQDYQKLRKEHLVSSEENITLKKINKE 1740

Query: 1484 RVKLIEELNVKITESVSL---NKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEI 1540
                + EL  K+  +  L     +V +L K L+   ++ +E    ++N E ++  L  +I
Sbjct: 1741 LSSKVHELEEKLYGNEQLRFWEDKVRDLMKELDNSQSENHEASRTIKNLEKDVKQLEIKI 1800

Query: 1541 TN 1542
             N
Sbjct: 1801 AN 1802



 Score = 93.9 bits (223), Expect = 3e-17
 Identities = 197/931 (21%), Positives = 388/931 (41%), Gaps = 94/931 (10%)

Query: 666  EQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKE--DIMNKLQNYIQENMDLTDK 723
            +Q+D   +S   + L I N+K   E+    ++D E  ++  DI +KL+   +   +L D+
Sbjct: 797  KQLDESRSSSLWMDLFI-NIKPLLEESVKVLEDAEMSEKVKDISSKLEEAEKSKSNLEDE 855

Query: 724  LEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEE 783
              K+  ++      +IN  E   I T       ++++DL +E  +SE +K  SRI   E 
Sbjct: 856  NSKLKEQE------QINKLEDEIITTT----NLVKDKDLKLEKAKSEEAKISSRIREFES 905

Query: 784  SIAVMEDRRYSLERKADQLGSYLQEKQK-------AYSEYTIQEDELVNRLAVLMDHDRV 836
             I  M+     L  +   L S L+E  +         S  T + D+  ++LA   D + V
Sbjct: 906  KINQMKQENNKLSEEKKLLDSKLKESSENSNRNIADLSSLTKERDDFKSKLA---DLELV 962

Query: 837  VEKQLLE-IEHEN--KELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESES 893
            V+K  LE +E E   ++L+K++  L   +++    + DM+Q    L E+ ++  L     
Sbjct: 963  VKKHKLEKVEREKHIEDLKKEHASLKSSSES---KVEDMKQLSRKLEEEISKNSLI---L 1016

Query: 894  TKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKN 953
             K+++ L +++  LK +  + ++ +  K +EI++            +  +K+  E+  K 
Sbjct: 1017 PKHESLLDEVK-KLKDLLSKSESDLESKDREIQE-----------TMSKQKLFEEENIKV 1064

Query: 954  IEYVTQ-LEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEIN 1012
            +E   + L+ +++ +K+ I   N  VE+L     +L    ++K+  Q          EI 
Sbjct: 1065 LEGTNKALKKEVESHKDEIAQKNAQVEKLQIQVAKL--SSLEKETEQLNTLVTNQSLEIQ 1122

Query: 1013 KLNALLKQKDEEIIALNQKINNAQVSYMS---MVSDYESKLAQFTTKLENMEEEMQRVSK 1069
             L   L     E  +L+  +   +V Y +      +Y  K+   + KL  +EEE +   K
Sbjct: 1123 NLQEQLSDSVRENKSLSVVVEKLKVDYDAARIAKEEYSDKIFILSKKLSELEEEAR--EK 1180

Query: 1070 QLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVD 1129
            ++   ++ N+       E+   IK LK  + T  +   K E   +   +  + D  +N  
Sbjct: 1181 EI---EKENQPPDPAFVEEFAHIK-LKLNENTAALRKEKFENKKLVEELSMLRDRFHNES 1236

Query: 1130 XXXXXXXXXXXXLKVQEEEEFIQER---SVLQEQSAKLNTELQECYTKIIQLETLNTELT 1186
                            E  + + E      LQ Q    N++  E Y   IQ + LN  L+
Sbjct: 1237 QQDRSPIKQNELRSRTETLDSLHEEINSLKLQLQQEMSNSQRAENYAIDIQ-KKLN-RLS 1294

Query: 1187 GHDVVN-----QEQINQLKSKLEQLNTENDNLLS---TVAELRSSISSAVDQRGFEIAEL 1238
                +N     +++  + + ++ +L  + +  +S   + +E   SIS +        +  
Sbjct: 1295 ATRGINSWTDYEKKFRESQRRVSELEGKFEEFISADESFSEASRSISKSDSFGRISFSMT 1354

Query: 1239 WKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQE-ETNKIVTME-QVTSLQ 1296
                 AQ   D  KT    R +L+  +S+  +L   ++ S  E  + K    +  ++  +
Sbjct: 1355 SNSDFAQIYQDITKTLRTTREELTTSKSEILRLKSLLRESEDELYSAKTANFKTSISDYE 1414

Query: 1297 NKLQDKEEHLRNLQEKYADVINQIEIL--RSEIEDEKVAFX-XXXXXXXXXXXXXXXDLR 1353
            +KL         L+ K +D+ + +E+   RSE   +K+                   DL 
Sbjct: 1415 DKLAQLTVRHDTLRTKNSDLASNLELYKRRSEEYYDKLELAEAAVQISKRHEESALNDLN 1474

Query: 1354 TENQSYKQMQEQS------ILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTH 1407
                  K  +E++      I  I   N++L+++             ++ + + K+    H
Sbjct: 1475 ETKNQLKLAKEEARTSQIMIKEIRTNNSKLEETIQDKNFAMKQQEAKIKELKEKI--YYH 1532

Query: 1408 QLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKR----IEDLTYEKESELAILR 1463
            +   ++ E   K  E  ITL +      +    L++  K+    +EDLT EK++      
Sbjct: 1533 KKNYENKEKTDKYREEIITLNKELAFKTDTENSLIKDSKKLQLDLEDLTKEKKTLEEDYA 1592

Query: 1464 LKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQ 1523
            LK+ E+ N  ET       +  +L     +   +  +LNKQV+ L + +E   + TN+  
Sbjct: 1593 LKI-EHVNVLETRVDLLSNKSRQLENAQEINDRKIGNLNKQVSSLRELVE---SVTNQRD 1648

Query: 1524 TALENQEIEIVTLNDEITNLQNMVRASSSKI 1554
              LE +      L D+++ L + +  S +++
Sbjct: 1649 ELLETK----AKLEDQLSELTHKLDLSEAEL 1675



 Score = 72.5 bits (170), Expect = 9e-11
 Identities = 144/733 (19%), Positives = 300/733 (40%), Gaps = 49/733 (6%)

Query: 164  KMKIMETTILDLQEKINEKDQIIEAKNK----ATTXXXXXXXXXXXXXXXXXEDTKQQMT 219
            K+ I+   + +L+E+  EK+  IE +N+    A                      K +  
Sbjct: 1162 KIFILSKKLSELEEEAREKE--IEKENQPPDPAFVEEFAHIKLKLNENTAALRKEKFENK 1219

Query: 220  KMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELE 279
            K+ E    +   + +E Q+    I+  ++R S  E  + L E    EI+    +L QE+ 
Sbjct: 1220 KLVEELSMLRDRFHNESQQDRSPIKQNELR-SRTETLDSLHE----EINSLKLQLQQEMS 1274

Query: 280  QXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIR 339
                           L + S        T+ E+K       ++EL  K E     +    
Sbjct: 1275 NSQRAENYAIDIQKKLNRLSATRGINSWTDYEKKFRESQRRVSELEGKFEEFISADESFS 1334

Query: 340  QTNKELENKLATMGTESKAVSSPSKKGSPLIS-RKSGRNTASKMKSPWSQ-LSSETLNQD 397
            + ++ + +K  + G  S +++S S          K+ R T  ++ +  S+ L  ++L ++
Sbjct: 1335 EASRSI-SKSDSFGRISFSMTSNSDFAQIYQDITKTLRTTREELTTSKSEILRLKSLLRE 1393

Query: 398  TDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQ 457
            ++ ++   + A  +  I     D  DK   ++ +                L  +   E+ 
Sbjct: 1394 SEDELYSAKTANFKTSIS----DYEDKLAQLTVRHDTLRTKNSDLASNLELYKRRSEEYY 1449

Query: 458  QHME-GPSLIHVGTNTED--VNEIAKVQEQLKQELND-EIKDVNVKDLIEKLKSAEEQIT 513
              +E   + + +    E+  +N++ + + QLK    +     + +K++       EE I 
Sbjct: 1450 DKLELAEAAVQISKRHEESALNDLNETKNQLKLAKEEARTSQIMIKEIRTNNSKLEETI- 1508

Query: 514  QLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAE 573
               D+  A  +   K+K   K K+   +K  +N  K     +EI+ L +EL   +     
Sbjct: 1509 --QDKNFAMKQQEAKIKEL-KEKIYYHKKNYENKEKTDKYREEIITLNKELAFKTDTENS 1565

Query: 574  LEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELH-- 631
            L ++   LQL L D    +    + Y   IE  N+ ETR+  +S  +S++ +  QE++  
Sbjct: 1566 LIKDSKKLQLDLEDLTKEKKTLEEDYALKIEHVNVLETRVDLLS-NKSRQLENAQEINDR 1624

Query: 632  ---ILQQKYDEVEDKLADISQLQSDQVCSEIK-SVHLEEQIDALSASKKELALVIENLKL 687
                L ++   + + +  ++  + + + ++ K    L E    L  S+ ELA   +++ +
Sbjct: 1625 KIGNLNKQVSSLRELVESVTNQRDELLETKAKLEDQLSELTHKLDLSEAELAQTNKDMNI 1684

Query: 688  ------DKEQLYGTIK-DLENDKEDIMNKLQNYIQENMD-LTDKLEKMSAEKISELLAKI 739
                  ++ Q    IK +L   +  I +++Q+Y +   + L    E ++ +KI++ L+  
Sbjct: 1685 LRTHLENQRQESSEIKSELSQSRSSISSEMQDYQKLRKEHLVSSEENITLKKINKELSSK 1744

Query: 740  NHEEQSKI----QTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSL 795
             HE + K+    Q +F  D K+++    ++N +SE  +    I  LE+ +  +E +  + 
Sbjct: 1745 VHELEEKLYGNEQLRFWED-KVRDLMKELDNSQSENHEASRTIKNLEKDVKQLEIKIANE 1803

Query: 796  ERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKN 855
             +   +      + Q   S Y    D L N  +      R  E++ + ++     L+K+ 
Sbjct: 1804 AQLRKKYNDENFDYQNKVSHYKSSLDILQNEQSEKDLQIRTAERENINLKESKLSLEKE- 1862

Query: 856  QILLEENQNLQIS 868
              +LE  Q L I+
Sbjct: 1863 --VLELRQRLGIN 1873



 Score = 70.9 bits (166), Expect = 3e-10
 Identities = 185/994 (18%), Positives = 398/994 (40%), Gaps = 102/994 (10%)

Query: 143  DVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXX 202
            ++  LS+  KE+D+  S L     +++   L   EK+ E+++ IE   K           
Sbjct: 938  NIADLSSLTKERDDFKSKLADLELVVKKHKL---EKV-EREKHIEDLKKEHASLKSSSES 993

Query: 203  XXXXXXXXXEDTKQQMTK------MQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEA 256
                        +++++K        E+ +    + KD   +   D+ESKD  I      
Sbjct: 994  KVEDMKQLSRKLEEEISKNSLILPKHESLLDEVKKLKDLLSKSESDLESKDREIQETMSK 1053

Query: 257  NKLLEAARFEISLEHSK-LAQELEQXXXXXXXXXXXXXXLAKQ-----SIEPSCEEKTEI 310
             KL E    ++    +K L +E+E               L  Q     S+E   E+   +
Sbjct: 1054 QKLFEEENIKVLEGTNKALKKEVESHKDEIAQKNAQVEKLQIQVAKLSSLEKETEQLNTL 1113

Query: 311  EEKGSLEIANMTE-LTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPL 369
                SLEI N+ E L+  +   + L+  + +   + +         S  +   SKK S L
Sbjct: 1114 VTNQSLEIQNLQEQLSDSVRENKSLSVVVEKLKVDYDAARIAKEEYSDKIFILSKKLSEL 1173

Query: 370  ISRKSGRNTASKMKSPWSQLSSE------TLNQDT-----DKKINKNEIAKLEMVIQSLN 418
                  +    + + P      E       LN++T     +K  NK  + +L M+    +
Sbjct: 1174 EEEAREKEIEKENQPPDPAFVEEFAHIKLKLNENTAALRKEKFENKKLVEELSMLRDRFH 1233

Query: 419  KDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEI 478
             +       I + +            ++    +LQL+ +      +  +     + +N +
Sbjct: 1234 NESQQDRSPIKQNELRSRTETLDSLHEEINSLKLQLQQEMSNSQRAENYAIDIQKKLNRL 1293

Query: 479  AKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLK 538
            +  +  +    + E K    +  + +L+   E+    ++    A++++ K  S  ++   
Sbjct: 1294 SATR-GINSWTDYEKKFRESQRRVSELEGKFEEFISADESFSEASRSISKSDSFGRISFS 1352

Query: 539  QMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDV 598
                +  +F+++     + +R T E   L+   +E+   K  L+    +  S +      
Sbjct: 1353 MTSNS--DFAQIYQDITKTLRTTRE--ELTTSKSEILRLKSLLRESEDELYSAKTANFKT 1408

Query: 599  YKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSE 658
                 E + LA+  ++    L ++  DL   L + +++ +E  DK      L+  +   +
Sbjct: 1409 SISDYE-DKLAQLTVRH-DTLRTKNSDLASNLELYKRRSEEYYDK------LELAEAAVQ 1460

Query: 659  IKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENM 718
            I   H E  ++ L+ +K +L L  E  +  +      IK++  +     +KL+  IQ+  
Sbjct: 1461 ISKRHEESALNDLNETKNQLKLAKEEARTSQIM----IKEIRTNN----SKLEETIQDK- 1511

Query: 719  DLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRI 778
               +   K    KI EL  KI + +++                   EN E +  KY+  I
Sbjct: 1512 ---NFAMKQQEAKIKELKEKIYYHKKN------------------YENKE-KTDKYREEI 1549

Query: 779  CRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVE 838
              L + +A   D   SL + + +L   L++  K   + T++ED      A+ ++H  V+E
Sbjct: 1550 ITLNKELAFKTDTENSLIKDSKKLQLDLEDLTK--EKKTLEED-----YALKIEHVNVLE 1602

Query: 839  KQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQT 898
             ++  + +++++L+   +I   +  NL   +S +++   ++  +  R +L E+++ K + 
Sbjct: 1603 TRVDLLSNKSRQLENAQEINDRKIGNLNKQVSSLRELVESVTNQ--RDELLETKA-KLED 1659

Query: 899  QLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEK----YEKNI 954
            QL +L   L     E    + Q  K++  L      Q + +   K  L++       +  
Sbjct: 1660 QLSELTHKLDLSEAE----LAQTNKDMNILRTHLENQRQESSEIKSELSQSRSSISSEMQ 1715

Query: 955  EYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQS-PDYTEQYINEI-- 1011
            +Y    +  L   + NI    +N E  +K++ EL +K    +Q +   D     + E+  
Sbjct: 1716 DYQKLRKEHLVSSEENITLKKINKELSSKVH-ELEEKLYGNEQLRFWEDKVRDLMKELDN 1774

Query: 1012 -----NKLNALLKQKDEEIIALNQKI-NNAQV--SYMSMVSDYESKLAQFTTKLENMEEE 1063
                 ++ +  +K  ++++  L  KI N AQ+   Y     DY++K++ + + L+ ++ E
Sbjct: 1775 SQSENHEASRTIKNLEKDVKQLEIKIANEAQLRKKYNDENFDYQNKVSHYKSSLDILQNE 1834

Query: 1064 MQRVSKQLLDSKQHNEELQILVREQDDQIKELKE 1097
                  Q+  +++ N  L+      + ++ EL++
Sbjct: 1835 QSEKDLQIRTAERENINLKESKLSLEKEVLELRQ 1868


>UniRef50_Q54JG6 Cluster: Putative uncharacterized protein; n=1;
            Dictyostelium discoideum AX4|Rep: Putative
            uncharacterized protein - Dictyostelium discoideum AX4
          Length = 2037

 Score =  123 bits (296), Expect = 5e-26
 Identities = 242/1391 (17%), Positives = 544/1391 (39%), Gaps = 112/1391 (8%)

Query: 212  EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEH 271
            E++ +++T +Q    A+    K+  ++L K+ E        +EEA  +LEA   ++  E 
Sbjct: 290  EESSKKVTLLQNRLDAL----KEADKKLRKEHEDA---YHKMEEAYDILEADYQKVIKEF 342

Query: 272  SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKI-EL 330
             +  Q  +                  Q   P   +  +     +  + +  EL +++ ++
Sbjct: 343  DEFKQHTQANAQNQSFNGVGSSSDLSQMDIPILSDTVKERLSDATTLGSRDELRRELLDM 402

Query: 331  LEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGR-----NTASKMKSP 385
            ++  +   +    E + K       S  +    KK +PLI  ++        +  K+ + 
Sbjct: 403  IQRYDDLTKIALNEKKEKRYVQDHLSHILREVEKK-APLIHEQNREYQRLLKSQEKLLNS 461

Query: 386  WSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGK 445
            + QL S+            +E  KL+  I  L K +     ++ E              K
Sbjct: 462  YQQLQSQKETLSLKVTTISSENNKLKQEINDLQKQI---RCLLQEALEKKQLQSQSQLNK 518

Query: 446  DTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKL 505
                 Q     Q  + G S+++  T+T   + I  + + L    N E   +  +DL+ ++
Sbjct: 519  SQFNGQ-----QSTLFGNSVLNNSTSTSSDDSI--IPDSLITFTNIEELQLRNQDLLRQI 571

Query: 506  KSAEEQITQLND---EIDAANKNMIKVKSNHKLKLKQMQKTI---DNFSKVSDSNKEIVR 559
            +   + I   N+   +++ A K +  +K+  + + + +Q  +   D++  VS  N     
Sbjct: 572  RILSQDIQSHNENDKKLEMALKELDHLKTARERQAEMIQSLVKQRDHYKNVSSPN----- 626

Query: 560  LTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLL 619
             ++ ++ +           G + L  +   +  M+        I   N     +   S  
Sbjct: 627  -SQPINQVGNNNNNNSSSGGMMTLSDLSSSTNGMLNDSSMNGSINKNNNNNNSMND-SFN 684

Query: 620  ESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELA 679
             S K +            +   + L   S L   Q  +EI +  LE+   +    +K+  
Sbjct: 685  NSIKNNN-------NNNNNNNNNSLLSSSTLIQQQQSNEILTQELEKIKQSYQLLQKDYE 737

Query: 680  LVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKI 739
             V+++  +  ++L G I+ +      +  ++     EN    ++L+ +S + +      +
Sbjct: 738  QVMKDRSISDKELLGKIEQMREQNTSLKIQISQIQSENTIFKERLQ-ISTDSVKNQSQDL 796

Query: 740  NHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKA 799
               EQ + + Q  +DA ++ +   IEN+ S+LS+ +    + E  ++ ++     +    
Sbjct: 797  ---EQYRKKNQELMDAVVRHQQS-IENLNSQLSRSEEFKSQAELRLSNIKGENQLIRASE 852

Query: 800  DQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILL 859
            ++L     E  K  S   +  + L++++  L        K+  E E   +    +N + L
Sbjct: 853  ERL----IEMNKTLSLEKLSIENLLDKVNQLN-----ASKESSETELRRRI---ENDLTL 900

Query: 860  EENQNLQISLS---DMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQT 916
             E Q +Q+      + QQH    +   ++ + +     K + +L DL+ ++ ++    QT
Sbjct: 901  LETQRIQLKKELDQEKQQHKETSIAMTHQINESRERFEKKEKELSDLKESIIKLKVSEQT 960

Query: 917  LIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNM 976
            L+    ++I  LE + N   +S +R   ++       +       + L    NN  N   
Sbjct: 961  LL----QKITFLENQLN---QSELRYNTIIERTQSNQLTISPTTSSTLSTNNNNNNNQQQ 1013

Query: 977  NVEELNKMNLELIDKHVQKQQTQS-PDYTEQYINEINKLNALLKQKDEEIIALNQKINNA 1035
             +++  +   + +D  + K + +S  D   Q  + I    ++    + ++  L ++    
Sbjct: 1014 KLQQQQQQQQDNLDLSLAKSEIESLKDLLAQEKDNIVHYKSIAISNENDLSQLKEEYTKT 1073

Query: 1036 QVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKEL 1095
            +V     + D +++LA+     E ++E+  ++ K    S  H +++  ++ E+D  + E 
Sbjct: 1074 KVELEERLKDAQAELAK---SQETIKEQQIKLEKLENFSSSHQKDINSIIAEKDSILAEK 1130

Query: 1096 KETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEE--EEFIQE 1153
            ++     +  + K + + +              +            +KV  +  ++ ++ 
Sbjct: 1131 QQLYEKIQQ-LTKDQQLALDEAKLQHQLCRKATENYEREVVLHAEDIKVLPKLRDDLVEA 1189

Query: 1154 RSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNL 1213
            R  + +   K+++  QE       LE         + + ++QI +L+ +L+ L   N+ L
Sbjct: 1190 RKTINQMQIKIDSNSQE-------LEQAKQSWIQQEQLLKQQIQELEERLKDLKHHNNLL 1242

Query: 1214 LSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLL- 1272
             S +  +               +      L Q   D      EL VQ+ A E K  ++  
Sbjct: 1243 HSQIENINQQTQQIDRYSQLSSSSSVGNGLVQVSEDEINNLKEL-VQVQAREQKITEVKN 1301

Query: 1273 DSVQSSTQEETNKIVTMEQ-VTSLQNKLQDKEEHLRNLQ---EKYADVINQIEILRSEIE 1328
            +S+Q       + I   ++ + ++  KLQ+++E++R L     K+ +V+ Q+E +     
Sbjct: 1302 ESLQQENIRLKSTIAANQKAIETVTKKLQEEQENMRTLTVSTRKHQEVLAQLEQMN---- 1357

Query: 1329 DEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXX 1388
                 F                 ++   +  KQ Q+  +L + E N +L   +       
Sbjct: 1358 ----LFKESNIMLKDETRKLGAQVQELQEKLKQSQDH-LLPLTESNKKLLAENQILHNEI 1412

Query: 1389 XXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRI 1448
                  + +   KV +L ++ +  D E++QK  E   T  + N E   + QQL + +K++
Sbjct: 1413 EAQKIEITNWSGKVQKLLNKYQSIDPEVHQKLLETNETTIRENQE---LTQQLEDLKKQL 1469

Query: 1449 EDLTYEKESELAILR-LKMHENANHYETMQ-KESEIE-------RVKLIEELNVKITESV 1499
            EDL  + E        LK H      E ++ K+ ++E       + +L      ++  + 
Sbjct: 1470 EDLKKQLEDNKKQYEDLKKHTKHWKEEAVKFKKDKLELDQSLTQQKELFSTTKQQLDSNT 1529

Query: 1500 SLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVS 1559
            + N+Q  + N+ L +++   N  + A + Q  +    N+EI  L+  +  +    + +  
Sbjct: 1530 ATNEQTLKENQELRKKIQIANANKQANKQQIQQQQANNEEIEALKKQLEDTRKLAEDYKK 1589

Query: 1560 FASDTKQGRDE 1570
             A D K+  DE
Sbjct: 1590 LADDYKKLTDE 1600



 Score = 88.6 bits (210), Expect = 1e-15
 Identities = 261/1364 (19%), Positives = 547/1364 (40%), Gaps = 118/1364 (8%)

Query: 306  EKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNK---------ELENKLATMGTES 356
            EK  ++ K  +E  N   +T K +L + L   I + +K         EL+ + + + +  
Sbjct: 69   EKDYMDSKKDVEQLNKQNITIKKDL-QSLKLSIERESKSNTLNRFIDELQQEKSNLHSII 127

Query: 357  KAVSSPSKKGSPLISRKSGR-NTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQ 415
            +      K+ +  +S+ + R N   K KS    L S+ +  + +   N+ +I +L+  + 
Sbjct: 128  ERKEKDLKEETETVSKLTERLNEFIKEKS---DLKSKLITVENENSSNEFQIQRLKQEVN 184

Query: 416  SLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDV 475
             L K     E   S+K T           K+     L+L+ +   +   ++ +    +++
Sbjct: 185  ELRKQTTFLED--SQKQTTNNLFNEI---KELKSFNLELKLKNENQADEILKLNQINQNL 239

Query: 476  NEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKL 535
             +     E+  Q+LN+EIK +      EK++      T+LN + + A+    + + + K 
Sbjct: 240  KKQTSELEKKNQQLNEEIKKITT----EKVQMTSSFETELNSQKNLASLYQERSEESSK- 294

Query: 536  KLKQMQKTIDNF----SKVSDSNKEIVRLTEELHHL----SQKV-AELEEEKGNLQLHLV 586
            K+  +Q  +D       K+   +++     EE + +     QKV  E +E K + Q +  
Sbjct: 295  KVTLLQNRLDALKEADKKLRKEHEDAYHKMEEAYDILEADYQKVIKEFDEFKQHTQANAQ 354

Query: 587  DYD-SGRMIESDVYKKMIE-MENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKL 644
            +   +G    SD+ +  I  + +  + RL   + L S+  +L +EL  + Q+YD++  K+
Sbjct: 355  NQSFNGVGSSSDLSQMDIPILSDTVKERLSDATTLGSRD-ELRRELLDMIQRYDDL-TKI 412

Query: 645  ADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKE 704
            A   + +   V   +   H+  +++  +    E     + L   +E+L  + + L++ KE
Sbjct: 413  ALNEKKEKRYVQDHLS--HILREVEKKAPLIHEQNREYQRLLKSQEKLLNSYQQLQSQKE 470

Query: 705  DIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFG-IDAKIQERDLY 763
             +  K+     EN  L  ++  +  ++I  LL +   ++Q + Q+Q        Q+  L+
Sbjct: 471  TLSLKVTTISSENNKLKQEINDLQ-KQIRCLLQEALEKKQLQSQSQLNKSQFNGQQSTLF 529

Query: 764  IENIESELSKYKSRICRLEES------IAVMEDRRYSLERKADQLGSYLQEKQKAYSEYT 817
              ++ +  +   S    + +S      I  ++ R   L R+   L   +Q   +   +  
Sbjct: 530  GNSVLNNSTSTSSDDSIIPDSLITFTNIEELQLRNQDLLRQIRILSQDIQSHNENDKKLE 589

Query: 818  IQEDELVNRLAVLMDHDRVVEKQLLEIEH----ENKELQKKNQILLEENQNL----QISL 869
            +   EL +          +++  + + +H     +   Q  NQ+    N N      ++L
Sbjct: 590  MALKELDHLKTARERQAEMIQSLVKQRDHYKNVSSPNSQPINQVGNNNNNNSSSGGMMTL 649

Query: 870  SDMQQHYNALVEKA-----------NRTDLAESESTKYQTQLRDLESNLKRITHEHQTLI 918
            SD+    N ++  +           N   + +S +   +    +  +N         TLI
Sbjct: 650  SDLSSSTNGMLNDSSMNGSINKNNNNNNSMNDSFNNSIKNNNNNNNNNNNNSLLSSSTLI 709

Query: 919  VQKK-KEIEDLEIEFNTQIESAIRD--KKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLN 975
             Q++  EI   E+E   Q    ++   ++V+ ++   + E + ++E Q++E   +++   
Sbjct: 710  QQQQSNEILTQELEKIKQSYQLLQKDYEQVMKDRSISDKELLGKIE-QMREQNTSLKIQI 768

Query: 976  MNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNA 1035
              ++  N +  E +       + QS D  EQY  +  +L   + +  + I  LN +++ +
Sbjct: 769  SQIQSENTIFKERLQISTDSVKNQSQD-LEQYRKKNQELMDAVVRHQQSIENLNSQLSRS 827

Query: 1036 QVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKEL 1095
            +  + S      S +      +   EE +  ++K L   K   E L   V  Q +  KE 
Sbjct: 828  E-EFKSQAELRLSNIKGENQLIRASEERLIEMNKTLSLEKLSIENLLDKV-NQLNASKES 885

Query: 1096 KETKL--TFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQE 1153
             ET+L    E ++   E   I    E   +   + +             +  E++E  +E
Sbjct: 886  SETELRRRIENDLTLLETQRIQLKKELDQEKQQHKETSIAMTHQINESRERFEKKE--KE 943

Query: 1154 RSVLQEQSAKLNTELQECYTKIIQLET-LN-TELTGHDVVNQEQINQL---KSKLEQLNT 1208
             S L+E   KL    Q    KI  LE  LN +EL  + ++ + Q NQL    +    L+T
Sbjct: 944  LSDLKESIIKLKVSEQTLLQKITFLENQLNQSELRYNTIIERTQSNQLTISPTTSSTLST 1003

Query: 1209 ENDNLLSTVAELRSSISSAVDQRGFEIA----ELWKQHLAQRE---ADFQKTEHELRVQL 1261
             N+N  +   +L+       D     +A    E  K  LAQ +     ++         L
Sbjct: 1004 NNNNNNNQQQKLQQQQQQQQDNLDLSLAKSEIESLKDLLAQEKDNIVHYKSIAISNENDL 1063

Query: 1262 SAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIE 1321
            S  + +Y +    ++   ++   ++   ++    Q   Q K E L N    +   IN I 
Sbjct: 1064 SQLKEEYTKTKVELEERLKDAQAELAKSQETIKEQ---QIKLEKLENFSSSHQKDINSII 1120

Query: 1322 ILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQE----QSILNINEENAQL 1377
              +  I  EK                   + + ++Q  ++  E    + +L+  +     
Sbjct: 1121 AEKDSILAEKQQLYEKIQQLTKDQQLALDEAKLQHQLCRKATENYEREVVLHAEDIKVLP 1180

Query: 1378 KKSSXXXXXXXXXXXXRVN-DAEAKVLELTHQLELKDSEI----YQKTHEYTITLTQRND 1432
            K               ++  D+ ++ LE   Q  ++  ++     Q+  E    L   N+
Sbjct: 1181 KLRDDLVEARKTINQMQIKIDSNSQELEQAKQSWIQQEQLLKQQIQELEERLKDLKHHNN 1240

Query: 1433 ----EFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQ---KESEIERV 1485
                + EN+ QQ  + + R   L+        ++++   E  N  E +Q   +E +I  V
Sbjct: 1241 LLHSQIENINQQTQQID-RYSQLSSSSSVGNGLVQVSEDEINNLKELVQVQAREQKITEV 1299

Query: 1486 K--LIEELNVKITESVSLNKQVAE-LNKALEEEVAKTNEMQTALENQEIEIVTLNDEITN 1542
            K   +++ N+++  +++ N++  E + K L+EE      +  +    + E++   +++  
Sbjct: 1300 KNESLQQENIRLKSTIAANQKAIETVTKKLQEEQENMRTLTVSTRKHQ-EVLAQLEQMNL 1358

Query: 1543 LQN---MVRASSSKIQKHV-SFASDTKQGRDEQLDNT-MNKELL 1581
             +    M++  + K+   V       KQ +D  L  T  NK+LL
Sbjct: 1359 FKESNIMLKDETRKLGAQVQELQEKLKQSQDHLLPLTESNKKLL 1402



 Score = 87.8 bits (208), Expect = 2e-15
 Identities = 211/1135 (18%), Positives = 461/1135 (40%), Gaps = 97/1135 (8%)

Query: 491  DEIKDVNVKDLIEKLKSAEEQITQLNDEIDAAN-KNMIKVKSNHKLKLKQMQKT-IDNFS 548
            DE       + I  +  AE +I QLN  +++   K+ ++V ++ +L  +Q++K  +D+  
Sbjct: 19   DEYNQFIATNPIGIILKAEFKIRQLNQTLESIQAKSQVEVTNSQQL-FQQLEKDYMDSKK 77

Query: 549  KVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENL 608
             V   NK+ + + ++L  L  K++   E K N     +D    +  +S+++  +   E  
Sbjct: 78   DVEQLNKQNITIKKDLQSL--KLSIERESKSNTLNRFID--ELQQEKSNLHSIIERKEKD 133

Query: 609  AETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADIS-QLQS-DQVCSEIK--SVHL 664
             +   + +S L  +  + ++E   L+ K   VE++ +    Q+Q   Q  +E++  +  L
Sbjct: 134  LKEETETVSKLTERLNEFIKEKSDLKSKLITVENENSSNEFQIQRLKQEVNELRKQTTFL 193

Query: 665  EEQ----IDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDL 720
            E+      + L    KEL      LKL  E     I  L    +++  +     ++N  L
Sbjct: 194  EDSQKQTTNNLFNEIKELKSFNLELKLKNENQADEILKLNQINQNLKKQTSELEKKNQQL 253

Query: 721  TDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICR 780
             ++++K++ EK+     ++    ++++ +Q  + +  QER    E    +++  ++R+  
Sbjct: 254  NEEIKKITTEKV-----QMTSSFETELNSQKNLASLYQERS---EESSKKVTLLQNRLDA 305

Query: 781  LEESIAVM----EDRRYSLERKADQLGSYLQEKQKAYSEYTIQ-EDELVNRLAVLMDHDR 835
            L+E+   +    ED  + +E   D L +  Q+  K + E+    +    N+    +    
Sbjct: 306  LKEADKKLRKEHEDAYHKMEEAYDILEADYQKVIKEFDEFKQHTQANAQNQSFNGVGSSS 365

Query: 836  VVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTK 895
             + +  + I  +  + +  +   L     L+  L DM Q Y+ L      T +A +E  +
Sbjct: 366  DLSQMDIPILSDTVKERLSDATTLGSRDELRRELLDMIQRYDDL------TKIALNEKKE 419

Query: 896  YQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIE 955
                        KR   +H + I+++ ++   L  E N + +  ++ ++ L   Y++   
Sbjct: 420  ------------KRYVQDHLSHILREVEKKAPLIHEQNREYQRLLKSQEKLLNSYQQLQS 467

Query: 956  YVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLN 1015
                L  ++    +    L   + +L K    L+ + ++K+Q QS           ++LN
Sbjct: 468  QKETLSLKVTTISSENNKLKQEINDLQKQIRCLLQEALEKKQLQSQ----------SQLN 517

Query: 1016 ALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQL---- 1071
                   +  +  N  +NN+  S  S  S     L  F T +E ++   Q + +Q+    
Sbjct: 518  KSQFNGQQSTLFGNSVLNNS-TSTSSDDSIIPDSLITF-TNIEELQLRNQDLLRQIRILS 575

Query: 1072 LDSKQHNE---ELQILVREQDDQIKELKETKLTFEMNIPKTEG---MIISSTIEPMSDDA 1125
             D + HNE   +L++ ++E  D +K  +E +     ++ K       + S   +P++   
Sbjct: 576  QDIQSHNENDKKLEMALKEL-DHLKTARERQAEMIQSLVKQRDHYKNVSSPNSQPINQVG 634

Query: 1126 NNVDXXXXXXXXXXXXLKVQEEEEFIQERSV--LQEQSAKLNTELQECYTKIIQLETLNT 1183
            NN +                     + + S+     ++   N  + + +   I+    N 
Sbjct: 635  NNNNNNSSSGGMMTLSDLSSSTNGMLNDSSMNGSINKNNNNNNSMNDSFNNSIKNNNNNN 694

Query: 1184 ELTGHD-VVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQH 1242
                ++ +++   + Q +   E L  E + +  +   L+      +  R     EL  + 
Sbjct: 695  NNNNNNSLLSSSTLIQQQQSNEILTQELEKIKQSYQLLQKDYEQVMKDRSISDKELLGKI 754

Query: 1243 LAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDK 1302
               RE   Q T   L++Q+S  +S+     + +Q ST    N+   +EQ      +L D 
Sbjct: 755  EQMRE---QNT--SLKIQISQIQSENTIFKERLQISTDSVKNQSQDLEQYRKKNQELMDA 809

Query: 1303 EEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQM 1362
               +R+ Q+   ++ +Q+   RSE    +                   +   E      +
Sbjct: 810  V--VRH-QQSIENLNSQLS--RSEEFKSQAELRLSNIKGENQLIRASEERLIEMNKTLSL 864

Query: 1363 QEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHE 1422
            ++ SI N+ ++  QL  S             R  + +  +LE T +++LK  E+ Q+  +
Sbjct: 865  EKLSIENLLDKVNQLNASK----ESSETELRRRIENDLTLLE-TQRIQLK-KELDQEKQQ 918

Query: 1423 YTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEI 1482
            +  T      +    R++  + EK + DL  E   +L +    + +     E    +SE+
Sbjct: 919  HKETSIAMTHQINESRERFEKKEKELSDLK-ESIIKLKVSEQTLLQKITFLENQLNQSEL 977

Query: 1483 ERVKLIEEL-NVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEIT 1541
                +IE   + ++T S + +  ++  N     +  K  + Q   +   +++     EI 
Sbjct: 978  RYNTIIERTQSNQLTISPTTSSTLSTNNNNNNNQQQKLQQQQQQ-QQDNLDLSLAKSEIE 1036

Query: 1542 NLQNMVRASSSKIQKHVSFA----SDTKQGRDEQLDNTMNKELLDAVPRAELDLA 1592
            +L++++      I  + S A    +D  Q ++E     +  EL + +  A+ +LA
Sbjct: 1037 SLKDLLAQEKDNIVHYKSIAISNENDLSQLKEEYTKTKV--ELEERLKDAQAELA 1089



 Score = 83.8 bits (198), Expect = 4e-14
 Identities = 187/930 (20%), Positives = 388/930 (41%), Gaps = 81/930 (8%)

Query: 212  EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIE-------SKDVRISSLEEANKLLEAAR 264
            E  KQ    +Q+++  +  +     + LL  IE       S  ++IS ++  N + +  R
Sbjct: 723  EKIKQSYQLLQKDYEQVMKDRSISDKELLGKIEQMREQNTSLKIQISQIQSENTIFKE-R 781

Query: 265  FEISLEHSK-LAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTE 323
             +IS +  K  +Q+LEQ                +QSIE    + +  EE  S     ++ 
Sbjct: 782  LQISTDSVKNQSQDLEQYRKKNQELMDAVVR-HQQSIENLNSQLSRSEEFKSQAELRLSN 840

Query: 324  LTKKIELLEHLNCQIRQTNKELE-NKLATMGTESKAVS-SPSKKGSPLISRKSGRNTASK 381
            +  + +L+     ++ + NK L   KL+      K    + SK+ S    R+   N  + 
Sbjct: 841  IKGENQLIRASEERLIEMNKTLSLEKLSIENLLDKVNQLNASKESSETELRRRIENDLTL 900

Query: 382  MKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXX 441
            +++   QL  E    D +K+ +K     +   I    +    KE  +S+           
Sbjct: 901  LETQRIQLKKEL---DQEKQQHKETSIAMTHQINESRERFEKKEKELSD---LKESIIKL 954

Query: 442  XXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDL 501
               + TL+ ++     Q  +     +        N++  +       L+    + N +  
Sbjct: 955  KVSEQTLLQKITFLENQLNQSELRYNTIIERTQSNQLT-ISPTTSSTLSTNNNNNNNQQ- 1012

Query: 502  IEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNK-EIVRL 560
             +KL+  ++Q  Q N ++  A   +  +K      L Q +  I ++  ++ SN+ ++ +L
Sbjct: 1013 -QKLQQQQQQ-QQDNLDLSLAKSEIESLKD----LLAQEKDNIVHYKSIAISNENDLSQL 1066

Query: 561  TEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLE 620
             EE  +   KV ELEE   + Q  L       + E  +  K+ ++EN + +  K I+ + 
Sbjct: 1067 KEE--YTKTKV-ELEERLKDAQAELAKSQE-TIKEQQI--KLEKLENFSSSHQKDINSII 1120

Query: 621  SQKFDLVQELHILQQKYDEV--EDKLA-DISQLQSDQVCSEI-----KSVHLE-EQIDAL 671
            ++K  ++ E   L +K  ++  + +LA D ++LQ  Q+C +      + V L  E I  L
Sbjct: 1121 AEKDSILAEKQQLYEKIQQLTKDQQLALDEAKLQH-QLCRKATENYEREVVLHAEDIKVL 1179

Query: 672  SASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEK 731
               + +L    + +   + ++    ++LE  K+  + + Q   Q+  +L ++L+ +    
Sbjct: 1180 PKLRDDLVEARKTINQMQIKIDSNSQELEQAKQSWIQQEQLLKQQIQELEERLKDLKHHN 1239

Query: 732  --ISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVME 789
              +   +  IN + Q +I     + +     +  ++  E E++  K  +        + E
Sbjct: 1240 NLLHSQIENINQQTQ-QIDRYSQLSSSSSVGNGLVQVSEDEINNLKELVQVQAREQKITE 1298

Query: 790  DRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENK 849
             +  SL+++  +L S +   QKA    T +  E    +  L    R  ++ L ++E  N 
Sbjct: 1299 VKNESLQQENIRLKSTIAANQKAIETVTKKLQEEQENMRTLTVSTRKHQEVLAQLEQMN- 1357

Query: 850  ELQKKNQILLEEN--------QNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLR 901
             L K++ I+L++         Q LQ  L   Q H   L E +N+  LAE++    + + +
Sbjct: 1358 -LFKESNIMLKDETRKLGAQVQELQEKLKQSQDHLLPLTE-SNKKLLAENQILHNEIEAQ 1415

Query: 902  DLE-----SNLKRITHEHQTL---IVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKN 953
             +E       ++++ +++Q++   + QK  E  +  I  N ++   + D K   E  +K 
Sbjct: 1416 KIEITNWSGKVQKLLNKYQSIDPEVHQKLLETNETTIRENQELTQQLEDLKKQLEDLKKQ 1475

Query: 954  IEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINK 1013
            +E     + Q ++ K + ++      +  K  LEL     Q+++  S   T+Q ++    
Sbjct: 1476 LE---DNKKQYEDLKKHTKHWKEEAVKFKKDKLELDQSLTQQKELFST--TKQQLDSNTA 1530

Query: 1014 LNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLD 1073
             N    ++++E   L +KI  A  +  +     + + A          EE++ + KQL D
Sbjct: 1531 TNEQTLKENQE---LRKKIQIANANKQANKQQIQQQQAN--------NEEIEALKKQLED 1579

Query: 1074 SKQHNEELQILVREQDDQIKELKETKLTFE 1103
            +++  E+ + L  +      E K     FE
Sbjct: 1580 TRKLAEDYKKLADDYKKLTDEAKSKLKVFE 1609



 Score = 71.7 bits (168), Expect = 2e-10
 Identities = 153/857 (17%), Positives = 354/857 (41%), Gaps = 75/857 (8%)

Query: 91   SESLANTLKQKEILMEKIKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNT 150
            S+ L    K+ + LM+ + ++++  +  ++ + R               +L ++   +  
Sbjct: 793  SQDLEQYRKKNQELMDAVVRHQQSIENLNSQLSRSEEFKSQAEL-----RLSNIKGENQL 847

Query: 151  IKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEA-KNKATTXXXXXXXXXXXXXXX 209
            I+  +  L  +   + + + +I +L +K+N+ +   E+ + +                  
Sbjct: 848  IRASEERLIEMNKTLSLEKLSIENLLDKVNQLNASKESSETELRRRIENDLTLLETQRIQ 907

Query: 210  XXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISL 269
              ++  Q+  + +E  IAM  +  + ++R     E K+  +S L+E+   L+ +   +  
Sbjct: 908  LKKELDQEKQQHKETSIAMTHQINESRERF----EKKEKELSDLKESIIKLKVSEQTLLQ 963

Query: 270  EHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIE 329
            + + L  +L Q                + +I P+           +    N  +  ++ +
Sbjct: 964  KITFLENQLNQSELRYNTIIERTQS-NQLTISPTTSSTLSTNNNNN---NNQQQKLQQQQ 1019

Query: 330  LLEHLNCQIRQTNKELENKLATMGTESKAV---SSPSKKGSPLISRKSGRNTASK--MKS 384
              +  N  +     E+E+    +  E   +    S +      +S+     T +K  ++ 
Sbjct: 1020 QQQQDNLDLSLAKSEIESLKDLLAQEKDNIVHYKSIAISNENDLSQLKEEYTKTKVELEE 1079

Query: 385  PWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDL----VDKEYVISEKDTXXXXXXX 440
                  +E        K  + ++ KLE    S  KD+     +K+ +++EK         
Sbjct: 1080 RLKDAQAELAKSQETIKEQQIKLEKLENFSSSHQKDINSIIAEKDSILAEKQQLYEKIQQ 1139

Query: 441  XXXGKDTLIAQLQLEHQQHMEGPSLIH--VGTNTEDVNEIAKVQEQL---KQELND-EIK 494
                +   + + +L+HQ   +        V  + ED+  + K+++ L   ++ +N  +IK
Sbjct: 1140 LTKDQQLALDEAKLQHQLCRKATENYEREVVLHAEDIKVLPKLRDDLVEARKTINQMQIK 1199

Query: 495  -DVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKL------KLKQMQKTIDNF 547
             D N ++L +  +S  +Q   L  +I    + +  +K ++ L       + Q  + ID +
Sbjct: 1200 IDSNSQELEQAKQSWIQQEQLLKQQIQELEERLKDLKHHNNLLHSQIENINQQTQQIDRY 1259

Query: 548  SKVSDSNKE---IVRLTE-ELHHLS---------QKVAELEEE---KGNLQLHLVDYDSG 591
            S++S S+     +V+++E E+++L          QK+ E++ E   + N++L      + 
Sbjct: 1260 SQLSSSSSVGNGLVQVSEDEINNLKELVQVQAREQKITEVKNESLQQENIRLKSTIAANQ 1319

Query: 592  RMIESDVYKKMIEMENL----AETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADI 647
            + IE+   K   E EN+      TR     L + ++ +L +E +I+ +  DE     A +
Sbjct: 1320 KAIETVTKKLQEEQENMRTLTVSTRKHQEVLAQLEQMNLFKESNIMLK--DETRKLGAQV 1377

Query: 648  SQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIM 707
             +LQ     S+   + L E    L A  + L   IE  K++     G ++ L N  + I 
Sbjct: 1378 QELQEKLKQSQDHLLPLTESNKKLLAENQILHNEIEAQKIEITNWSGKVQKLLNKYQSID 1437

Query: 708  NKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDL--YIE 765
             ++   + E  + T +  +   +++ +L  ++   E  K Q +   D K Q  DL  + +
Sbjct: 1438 PEVHQKLLETNETTIRENQELTQQLEDLKKQL---EDLKKQLE---DNKKQYEDLKKHTK 1491

Query: 766  NIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVN 825
            + + E  K+K     L++S+   ++   + +++ D           A +E T++E++ + 
Sbjct: 1492 HWKEEAVKFKKDKLELDQSLTQQKELFSTTKQQLDS--------NTATNEQTLKENQELR 1543

Query: 826  RLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANR 885
            +   + + ++   KQ ++ +  N E  +  +  LE+ + L      +   Y  L ++A +
Sbjct: 1544 KKIQIANANKQANKQQIQQQQANNEEIEALKKQLEDTRKLAEDYKKLADDYKKLTDEA-K 1602

Query: 886  TDLAESESTKYQTQLRD 902
            + L   ES K  + L +
Sbjct: 1603 SKLKVFESMKKASALNN 1619


>UniRef50_Q22AQ6 Cluster: Putative uncharacterized protein; n=1;
            Tetrahymena thermophila SB210|Rep: Putative
            uncharacterized protein - Tetrahymena thermophila SB210
          Length = 1845

 Score =  123 bits (296), Expect = 5e-26
 Identities = 181/872 (20%), Positives = 401/872 (45%), Gaps = 105/872 (12%)

Query: 475  VNEIAKVQEQLKQELNDEIKDVNVKD--LIEKLKSAEEQITQLNDEIDAANKNMIKVKSN 532
            V E  + Q   +++L DE+ + + K+  + E+ ++ + ++  LN++I+     M+K+ + 
Sbjct: 486  VREAREAQLNAEKQLTDELTNRSQKETQISERYETQKTELILLNNKIE-----MLKLDAE 540

Query: 533  HKLKLK-QMQKTIDNFSKVSDSN-KEI-VRLTEELHHLSQKVAELEEEKGNLQLHLVDYD 589
               K K  ++K +DN     +   KE+ + + +++  L +    LE+E    + +L+  +
Sbjct: 541  RICKEKYNLEKLVDNLKVEHEEKLKEVKMEMKKKIKELKKTNQNLEKEISMKENNLLQIE 600

Query: 590  SGRMIESD----VYKKMIEMENLAETRLKAIS-----LLESQ-KFDLV-QELHILQQKYD 638
            +  +I S     +  K++E+++L E +++ +      L E Q K+DL+ QEL   +Q ++
Sbjct: 601  NEGVILSKNTNALSDKVLELQSLLEKKIEEVREKDKVLQEEQNKYDLLSQELQTQRQSFE 660

Query: 639  EVEDKLADIS-----QLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLY 693
               ++L + +     QL    +  +  SV  E     L   K+E    I     +   L 
Sbjct: 661  VTINQLQNSNKSIQEQLLRKNILLDSASVSFEVNQKCLIKEKEEALEKIIKCNEEISHLK 720

Query: 694  GTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQ--SKIQTQF 751
             T+++ +   ED+  K+ +   +N ++  + EK+ +E + ++    + ++   ++I    
Sbjct: 721  KTLEEQQFKNEDLQEKINDLRLQNENMLLQAEKLRSENLEQMRIFQDTQKSLNNRIDQLI 780

Query: 752  GIDAKIQERDLYIENIESELSKYKSRICRLE-ESIAVMEDRRYSLERKADQLGSYLQEKQ 810
              + K+Q+ +L   N+     K+     +L+ E + +++D    ++ K       L EK 
Sbjct: 781  SENNKLQQTELL--NLNERCDKFNLMFQQLQQEKLQLIQDNSIIVQDKIT-----LSEKV 833

Query: 811  KAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLS 870
            +      +Q++  ++ L+ + ++D    K+++E+++E  +L  +   L +EN  L+  + 
Sbjct: 834  RE-----LQQNN-IDLLSKIHNYDNQKNKEIVELKYELDQLINQKDKLKQENHLLEQEIQ 887

Query: 871  DMQQHYNALVEKANRTDLAESESTKYQTQLRDL--ESNLK-RITHEHQTLIVQKKKEIED 927
            + + + N+  E+ N   +   E  ++Q QL  L  ES LK    H+ + LI+ +K +I+ 
Sbjct: 888  EYKNNINSYKEQINSFIV---EINQFQLQLDTLKQESRLKTEQIHQQENLILNQKNQIDT 944

Query: 928  LEIEFNTQIESAIRDKKVLNEKYEKNIEY-VTQLEAQL----QEYKNNIENLNMNVEELN 982
            L             +K  L+++ E+ I+Y + +LE +     Q+Y+N I+NL +N E+L 
Sbjct: 945  LV------------EKSYLDQESERLIDYKLKELEDEKIACNQKYENAIQNLRINEEQLR 992

Query: 983  KMNLELIDKHVQKQ--------QTQSPDYTEQYIN----EINKLNALLKQKDEEIIALNQ 1030
             ++++L  K  Q +         TQ  +     IN    +INKL+A LK+ ++ + A+  
Sbjct: 993  SLSIQLNQKSEQVKILEDYKNVLTQEKEQQLVEINKCHLQINKLSAELKEAEQSLQAVQD 1052

Query: 1031 KINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDD 1090
            K  + QVS  S      +   Q++ +L   ++ + +  +QL     +  E   ++ E   
Sbjct: 1053 KCKDLQVSLNSASDQIFNIKQQYSQELIEKDQMILQCKEQLRYQCMNQIEQSQVLEEMTS 1112

Query: 1091 QIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEF 1150
            +I++ K  +   + N+ K    +    I+ + D  N +               +Q++ + 
Sbjct: 1113 EIEKQKNLEQQVQ-NLRKENEKLELEQIKLLKD--NEI----------LRLHLIQKQPDN 1159

Query: 1151 IQERSVLQEQS---AKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLN 1207
             Q   +L+E +    + + E+Q    K+ Q + +  + T     N+ QI     K+ +  
Sbjct: 1160 CQIELILEEHNQILTEYHEEIQRLKDKLQQKQQILEKFT-----NKIQIQ--SDKIAENE 1212

Query: 1208 TENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESK 1267
             E  NL S +A  +    + +++   ++ ++ +Q+  Q++       H L       +S 
Sbjct: 1213 KEISNLQSFIANGKKHYENLIEEYQLKMDQMQQQN-TQQQIVLNNQIHLLMQDKQQMKSH 1271

Query: 1268 YEQLLDSVQSSTQEETNKIVTMEQVTSLQNKL 1299
                LD +Q    + T   + M Q+   + +L
Sbjct: 1272 ----LDQIQKEMSDITQLSLKMSQIPQTRTQL 1299



 Score =  122 bits (293), Expect = 1e-25
 Identities = 219/1040 (21%), Positives = 454/1040 (43%), Gaps = 107/1040 (10%)

Query: 297  KQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTES 356
            K  IE   E+   ++ K   E+  +    +  ++LE  N QI+Q N + E       +  
Sbjct: 351  KMEIELLKEQNDALKSKVD-ELTLLVNDKEMQKILEEKNFQIKQVNADYEQLAEKYASIE 409

Query: 357  KAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQS 416
            KA      +   L  +     ++   +SP     +  L Q+ +KK+   E    E  IQS
Sbjct: 410  KAYDLMHIEYDSLNQKYLELQSS---RSP-RDTENVDLVQELEKKVLYMEEKMREDEIQS 465

Query: 417  LNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVN 476
             NK    K  V+ ++++           ++   AQL  E Q   E   L +       ++
Sbjct: 466  -NK---MKMVVLKQEESISILENLVREARE---AQLNAEKQLTDE---LTNRSQKETQIS 515

Query: 477  EIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIK-VKSNHKL 535
            E  + Q+     LN++I+ + +    E++   +  + +L D +   ++  +K VK   K 
Sbjct: 516  ERYETQKTELILLNNKIEMLKLD--AERICKEKYNLEKLVDNLKVEHEEKLKEVKMEMKK 573

Query: 536  KLKQMQKTIDNFSK-VSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMI 594
            K+K+++KT  N  K +S     ++++  E   LS+    L ++   LQ  L++     + 
Sbjct: 574  KIKELKKTNQNLEKEISMKENNLLQIENEGVILSKNTNALSDKVLELQ-SLLEKKIEEVR 632

Query: 595  ESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQ 654
            E D   K+++ E      L      + Q F++   ++ LQ     +++      QL    
Sbjct: 633  EKD---KVLQEEQNKYDLLSQELQTQRQSFEVT--INQLQNSNKSIQE------QLLRKN 681

Query: 655  VCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYI 714
            +  +  SV  E     L   K+E    I     +   L  T+++ +   ED+  K+ +  
Sbjct: 682  ILLDSASVSFEVNQKCLIKEKEEALEKIIKCNEEISHLKKTLEEQQFKNEDLQEKINDLR 741

Query: 715  QENMDLTDKLEKMSAEKISE--LLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELS 772
             +N ++  + EK+ +E + +  +         ++I      + K+Q+ +L   N+     
Sbjct: 742  LQNENMLLQAEKLRSENLEQMRIFQDTQKSLNNRIDQLISENNKLQQTELL--NLNERCD 799

Query: 773  KYKSRICRL-EESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLM 831
            K+     +L +E + +++D    ++ K       L EK +      +Q++  ++ L+ + 
Sbjct: 800  KFNLMFQQLQQEKLQLIQDNSIIVQDKIT-----LSEKVR-----ELQQNN-IDLLSKIH 848

Query: 832  DHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAES 891
            ++D    K+++E+++E  +L  +   L +EN  L+  + + + + N+  E+ N + + E 
Sbjct: 849  NYDNQKNKEIVELKYELDQLINQKDKLKQENHLLEQEIQEYKNNINSYKEQIN-SFIVEI 907

Query: 892  ESTKYQTQLRDLESNLK-RITHEHQTLIVQKKKEIEDL-EIEFNTQIESAIRDKKVLNEK 949
               + Q      ES LK    H+ + LI+ +K +I+ L E  +  Q    + D K L E 
Sbjct: 908  NQFQLQLDTLKQESRLKTEQIHQQENLILNQKNQIDTLVEKSYLDQESERLIDYK-LKEL 966

Query: 950  YEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYIN 1009
             ++ I       A  Q+Y+N I+NL +N E+L  ++++L       Q+++     E Y  
Sbjct: 967  EDEKI-------ACNQKYENAIQNLRINEEQLRSLSIQL------NQKSEQVKILEDY-- 1011

Query: 1010 EINKLNALLKQKDEEIIALNQKINNAQVSYMSM-VSDYESKLAQFTTKLENMEEEMQRVS 1068
                 N L ++K+++++ +N+   + Q++ +S  + + E  L     K ++++  +   S
Sbjct: 1012 ----KNVLTQEKEQQLVEINK--CHLQINKLSAELKEAEQSLQAVQDKCKDLQVSLNSAS 1065

Query: 1069 KQLLDSKQHNEELQILVREQDDQIKELKETKLTFE-MNIPKTEGMIISSTIEPMSDDANN 1127
             Q+ + KQ   +  I   E+D  I + KE +L ++ MN  +   ++   T E   +   N
Sbjct: 1066 DQIFNIKQQYSQELI---EKDQMILQCKE-QLRYQCMNQIEQSQVLEEMTSE--IEKQKN 1119

Query: 1128 VDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTG 1187
            ++            L++ E+ + +++  +L+     +  +   C  ++I LE  N  LT 
Sbjct: 1120 LEQQVQNLRKENEKLEL-EQIKLLKDNEILRLH--LIQKQPDNCQIELI-LEEHNQILTE 1175

Query: 1188 HDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQRE 1247
            +     E+I +LK KL+Q       +L          S  + +   EI+ L +  +A  +
Sbjct: 1176 Y----HEEIQRLKDKLQQ----KQQILEKFTNKIQIQSDKIAENEKEISNL-QSFIANGK 1226

Query: 1248 ADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLR 1307
              ++    E       ++ K +Q+    Q +TQ++   IV   Q+  L    Q  + HL 
Sbjct: 1227 KHYENLIEE-------YQLKMDQM---QQQNTQQQ---IVLNNQIHLLMQDKQQMKSHLD 1273

Query: 1308 NLQEKYADVINQIEILRSEI 1327
             +Q++ +D I Q+ +  S+I
Sbjct: 1274 QIQKEMSD-ITQLSLKMSQI 1292



 Score =  114 bits (275), Expect = 2e-23
 Identities = 207/1038 (19%), Positives = 444/1038 (42%), Gaps = 111/1038 (10%)

Query: 557  IVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEME-NLAETRLKA 615
            I  LT E    SQ++ E  E    + +  +   +G++  + V  KMI  +    ++ LK 
Sbjct: 185  ITSLTFEKKPASQQLKENNENCLGVVIQNLKQYAGQLGPTLVSNKMIPQQIPFIQSPLKT 244

Query: 616  ISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQS-DQVCSEI--KSVHLEEQIDALS 672
                  +K D +  + IL Q  + +++ +    QL + DQ   +I  K    E+ ++   
Sbjct: 245  SLQSSGKKTDKIVNVQILSQNQN-IQNAVLQNQQLNAQDQAALKIAEKEAQKEKNLNLFK 303

Query: 673  AS----------KKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTD 722
             S          + EL  +   LK DK+ +YG+   L  D+E ++ +++  I+   +  D
Sbjct: 304  ESSIKFITNTDLEAELKDLAHLLKRDKD-MYGSNIMLTTDREQVIPEMKMEIELLKEQND 362

Query: 723  KLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLE 782
             L+     K+ EL   +N +E  KI         ++E++  I+ + ++  +   +   +E
Sbjct: 363  ALKS----KVDELTLLVNDKEMQKI---------LEEKNFQIKQVNADYEQLAEKYASIE 409

Query: 783  ESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLA--VLMDHDRVVEKQ 840
            ++  +M     SL +K      YL E Q + S    +  +LV  L   VL   +++ E +
Sbjct: 410  KAYDLMHIEYDSLNQK------YL-ELQSSRSPRDTENVDLVQELEKKVLYMEEKMREDE 462

Query: 841  LLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQL 900
            +   + +   L+++  I + EN   +   + +        E  NR+      S +Y+TQ 
Sbjct: 463  IQSNKMKMVVLKQEESISILENLVREAREAQLNAEKQLTDELTNRSQKETQISERYETQK 522

Query: 901  RDLE--SNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVT 958
             +L   +N   +       I ++K  +E L      + E  +++ K+  +K  K ++   
Sbjct: 523  TELILLNNKIEMLKLDAERICKEKYNLEKLVDNLKVEHEEKLKEVKMEMKKKIKELKKTN 582

Query: 959  Q-LEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNAL 1017
            Q LE ++   +NN+  +      L+K    L DK ++ Q        E+ I E+ + + +
Sbjct: 583  QNLEKEISMKENNLLQIENEGVILSKNTNALSDKVLELQSL-----LEKKIEEVREKDKV 637

Query: 1018 LKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQH 1077
            L+++  +   L+Q++   + S+       E  + Q     ++++E++ R    LLDS   
Sbjct: 638  LQEEQNKYDLLSQELQTQRQSF-------EVTINQLQNSNKSIQEQLLR-KNILLDSASV 689

Query: 1078 NEEL--QILVREQDDQIK-------ELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNV 1128
            + E+  + L++E+++ ++       E+   K T E    K E +        + ++   +
Sbjct: 690  SFEVNQKCLIKEKEEALEKIIKCNEEISHLKKTLEEQQFKNEDLQEKINDLRLQNENMLL 749

Query: 1129 DXXXXXXXXXXXXLKVQEEEEFIQER--SVLQEQSAKLNTEL----QECYTKIIQLETLN 1182
                            Q+ ++ +  R   ++ E +    TEL    + C    +  + L 
Sbjct: 750  QAEKLRSENLEQMRIFQDTQKSLNNRIDQLISENNKLQQTELLNLNERCDKFNLMFQQLQ 809

Query: 1183 TE----LTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAEL 1238
             E    +  + ++ Q++I  L  K+ +L   N +LLS +    +  +  + +  +E+ +L
Sbjct: 810  QEKLQLIQDNSIIVQDKIT-LSEKVRELQQNNIDLLSKIHNYDNQKNKEIVELKYELDQL 868

Query: 1239 WKQ--------HLAQREA-DFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTM 1289
              Q        HL ++E  +++   +  + Q+++F  +  Q    +Q  T ++ +++ T 
Sbjct: 869  INQKDKLKQENHLLEQEIQEYKNNINSYKEQINSFIVEINQF--QLQLDTLKQESRLKT- 925

Query: 1290 EQVTSLQNKLQDKEEHLRNLQEK-YADVINQ--IEILRSEIEDEKVAFXXXXXXXXXXXX 1346
            EQ+   +N + +++  +  L EK Y D  ++  I+    E+EDEK+A             
Sbjct: 926  EQIHQQENLILNQKNQIDTLVEKSYLDQESERLIDYKLKELEDEKIACNQKYENAIQNLR 985

Query: 1347 XXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELT 1406
                 LR+ +    Q  EQ  +  + +N  L +              ++N   A++ E  
Sbjct: 986  INEEQLRSLSIQLNQKSEQVKILEDYKNV-LTQEKEQQLVEINKCHLQINKLSAELKEAE 1044

Query: 1407 HQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKM 1466
              L+     +  K  +  ++L   +D+  N++QQ   Y + +       E +  IL+ K 
Sbjct: 1045 QSLQA----VQDKCKDLQVSLNSASDQIFNIKQQ---YSQELI------EKDQMILQCK- 1090

Query: 1467 HENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTAL 1526
                  Y+ M   ++IE+ +++EE+  +I +  +L +QV  L K  E E  +  +++   
Sbjct: 1091 --EQLRYQCM---NQIEQSQVLEEMTSEIEKQKNLEQQVQNLRK--ENEKLELEQIKLLK 1143

Query: 1527 ENQEIEIVTLNDEITNLQ 1544
            +N+ + +  +  +  N Q
Sbjct: 1144 DNEILRLHLIQKQPDNCQ 1161



 Score = 96.7 bits (230), Expect = 5e-18
 Identities = 166/776 (21%), Positives = 355/776 (45%), Gaps = 72/776 (9%)

Query: 392  ETLNQDTDKKIN--KNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDT-L 448
            + L  + ++K+   K E+ K    ++  N++L +KE  + E +            K+T  
Sbjct: 554  DNLKVEHEEKLKEVKMEMKKKIKELKKTNQNL-EKEISMKENNLLQIENEGVILSKNTNA 612

Query: 449  IAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIK--DVNVKDLIEKLK 506
            ++   LE Q  +E   +  V    + + E     + L QEL  + +  +V +  L    K
Sbjct: 613  LSDKVLELQSLLE-KKIEEVREKDKVLQEEQNKYDLLSQELQTQRQSFEVTINQLQNSNK 671

Query: 507  SAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHH 566
            S +EQ+ + N  +D+A+   +  + N K  +K+ ++ ++   K+   N+EI  L + L  
Sbjct: 672  SIQEQLLRKNILLDSAS---VSFEVNQKCLIKEKEEALE---KIIKCNEEISHLKKTLEE 725

Query: 567  LSQKVAELEEEKGNLQLHLVDYD-SGRMIESDVYKKMIEMENLAETRLKAISLLESQKFD 625
               K  +L+E+  +L+L   +       + S+  ++M   ++  ++    I  L S+   
Sbjct: 726  QQFKNEDLQEKINDLRLQNENMLLQAEKLRSENLEQMRIFQDTQKSLNNRIDQLISENNK 785

Query: 626  LVQ-ELHILQQKYDEVEDKLADISQ-----LQSDQVCSEIKSVHLEEQIDALSASKKELA 679
            L Q EL  L ++ D+       + Q     +Q + +  + K + L E++  L  +  +L 
Sbjct: 786  LQQTELLNLNERCDKFNLMFQQLQQEKLQLIQDNSIIVQDK-ITLSEKVRELQQNNIDLL 844

Query: 680  LVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKI 739
              I N    K +    I +L+ + + ++N+     QEN  L  ++++     I+    +I
Sbjct: 845  SKIHNYDNQKNK---EIVELKYELDQLINQKDKLKQENHLLEQEIQEYK-NNINSYKEQI 900

Query: 740  NHEEQSKIQTQFGIDAKIQERDLYIENI---ESELSKYKSRICRL-EESIAVMEDRR--- 792
            N       Q Q  +D   QE  L  E I   E+ +   K++I  L E+S    E  R   
Sbjct: 901  NSFIVEINQFQLQLDTLKQESRLKTEQIHQQENLILNQKNQIDTLVEKSYLDQESERLID 960

Query: 793  YSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQ 852
            Y L+   D+  +  Q+ + A     I E++L  R   +  + +  + ++LE +++N   Q
Sbjct: 961  YKLKELEDEKIACNQKYENAIQNLRINEEQL--RSLSIQLNQKSEQVKILE-DYKNVLTQ 1017

Query: 853  KKNQILLEENQ-NLQIS-----LSDMQQHYNALVEKANRTDLAESEST--------KYQT 898
            +K Q L+E N+ +LQI+     L + +Q   A+ +K     ++ + ++        +Y  
Sbjct: 1018 EKEQQLVEINKCHLQINKLSAELKEAEQSLQAVQDKCKDLQVSLNSASDQIFNIKQQYSQ 1077

Query: 899  QLRDLESNLKRITHE--HQTLI-VQKKKEIEDL--EIEFNTQIESAIRDKKVLNEKYE-K 952
            +L + +  + +   +  +Q +  +++ + +E++  EIE    +E  +++ +  NEK E +
Sbjct: 1078 ELIEKDQMILQCKEQLRYQCMNQIEQSQVLEEMTSEIEKQKNLEQQVQNLRKENEKLELE 1137

Query: 953  NIEYVTQLEAQ----LQEYKNNIENLNMNVEELNKMNLELIDK--HVQKQQTQSPDYTEQ 1006
             I+ +   E      +Q+  +N + + + +EE N++  E  ++   ++ +  Q     E+
Sbjct: 1138 QIKLLKDNEILRLHLIQKQPDNCQ-IELILEEHNQILTEYHEEIQRLKDKLQQKQQILEK 1196

Query: 1007 YINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQR 1066
            + N+I   +  + + ++EI  L   I N +  Y +++ +Y+ K+ Q   +    +  +  
Sbjct: 1197 FTNKIQIQSDKIAENEKEISNLQSFIANGKKHYENLIEEYQLKMDQMQQQNTQQQIVLNN 1256

Query: 1067 VSKQLLDSKQHNEELQILVREQDDQI-KELKE-TKLTFEMN-IPKTEGMIISSTIE 1119
                L+  KQ        ++   DQI KE+ + T+L+ +M+ IP+T   +  S+I+
Sbjct: 1257 QIHLLMQDKQQ-------MKSHLDQIQKEMSDITQLSLKMSQIPQTRTQLCESSIK 1305



 Score = 84.2 bits (199), Expect = 3e-14
 Identities = 158/867 (18%), Positives = 369/867 (42%), Gaps = 67/867 (7%)

Query: 153  EKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXE 212
            E  + +  L+ K+  ME  + + + + N+   ++  + ++ +                 +
Sbjct: 439  ENVDLVQELEKKVLYMEEKMREDEIQSNKMKMVVLKQEESISILENLVREAREAQLNAEK 498

Query: 213  DTKQQMTKMQENFIAMEAEWKDEKQRLL---KDIESKDVRISSLEEANKLLEAARFEISL 269
                ++T   +    +   ++ +K  L+     IE   +    + +    LE     + +
Sbjct: 499  QLTDELTNRSQKETQISERYETQKTELILLNNKIEMLKLDAERICKEKYNLEKLVDNLKV 558

Query: 270  EHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKI- 328
            EH +  +E++                 ++ I        +IE +G +   N   L+ K+ 
Sbjct: 559  EHEEKLKEVKMEMKKKIKELKKTNQNLEKEISMKENNLLQIENEGVILSKNTNALSDKVL 618

Query: 329  ---ELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISR--KSGRNTASKMK 383
                LLE    ++R+ +K L+ +       S+ + +  +     I++   S ++   ++ 
Sbjct: 619  ELQSLLEKKIEEVREKDKVLQEEQNKYDLLSQELQTQRQSFEVTINQLQNSNKSIQEQLL 678

Query: 384  SPWSQLSSETLNQDTDKK-INKNEIAKLEMVIQSLNKDLVDKEYVISEK----DTXXXXX 438
                 L S +++ + ++K + K +   LE +I+  N+++   +  + E+    +      
Sbjct: 679  RKNILLDSASVSFEVNQKCLIKEKEEALEKIIKC-NEEISHLKKTLEEQQFKNEDLQEKI 737

Query: 439  XXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNV 498
                   + ++ Q +    +++E   +    T     N I ++  +  +    E+  +N+
Sbjct: 738  NDLRLQNENMLLQAEKLRSENLEQMRIFQ-DTQKSLNNRIDQLISENNKLQQTEL--LNL 794

Query: 499  KDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKT-IDNFSKV----SDS 553
             +  +K     +Q+ Q   ++   N  +++ K     K++++Q+  ID  SK+    +  
Sbjct: 795  NERCDKFNLMFQQLQQEKLQLIQDNSIIVQDKITLSEKVRELQQNNIDLLSKIHNYDNQK 854

Query: 554  NKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSG-RMIESDVYKKMIEMEN--LAE 610
            NKEIV L  EL  L  +  +L++E   L+  + +Y +     +  +   ++E+    L  
Sbjct: 855  NKEIVELKYELDQLINQKDKLKQENHLLEQEIQEYKNNINSYKEQINSFIVEINQFQLQL 914

Query: 611  TRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDA 670
              LK  S L++++    + L IL QK +++ D L + S L  DQ    +    L+E  D 
Sbjct: 915  DTLKQESRLKTEQIHQQENL-ILNQK-NQI-DTLVEKSYL--DQESERLIDYKLKELEDE 969

Query: 671  LSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAE 730
              A  ++    I+NL++++EQL      L N K + +  L++Y  +N+ LT + E+   E
Sbjct: 970  KIACNQKYENAIQNLRINEEQLRSLSIQL-NQKSEQVKILEDY--KNV-LTQEKEQQLVE 1025

Query: 731  ------KISELLAKINHEEQSKIQTQF---GIDAKIQERDLYIENIES----ELSKYKSR 777
                  +I++L A++   EQS    Q     +   +      I NI+     EL +    
Sbjct: 1026 INKCHLQINKLSAELKEAEQSLQAVQDKCKDLQVSLNSASDQIFNIKQQYSQELIEKDQM 1085

Query: 778  ICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTI----QEDELVNRLAVLMDH 833
            I + +E +      +    +  +++ S + EKQK   +       + ++L      L+  
Sbjct: 1086 ILQCKEQLRYQCMNQIEQSQVLEEMTSEI-EKQKNLEQQVQNLRKENEKLELEQIKLLKD 1144

Query: 834  DRVVEKQLLEIEHENKE----LQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLA 889
            + ++   L++ + +N +    L++ NQIL E ++ +Q     +QQ    L +  N+  + 
Sbjct: 1145 NEILRLHLIQKQPDNCQIELILEEHNQILTEYHEEIQRLKDKLQQKQQILEKFTNKIQIQ 1204

Query: 890  ESESTKYQTQLRDLES-------NLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRD 942
              +  + + ++ +L+S       + + +  E+Q  + Q +++    +I  N QI   ++D
Sbjct: 1205 SDKIAENEKEISNLQSFIANGKKHYENLIEEYQLKMDQMQQQNTQQQIVLNNQIHLLMQD 1264

Query: 943  KKVLN---EKYEKNIEYVTQLEAQLQE 966
            K+ +    ++ +K +  +TQL  ++ +
Sbjct: 1265 KQQMKSHLDQIQKEMSDITQLSLKMSQ 1291



 Score = 57.2 bits (132), Expect = 3e-06
 Identities = 129/687 (18%), Positives = 283/687 (41%), Gaps = 54/687 (7%)

Query: 151  IKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXX 210
            ++EKD  L   Q K  ++   +   ++        ++  NK+                  
Sbjct: 631  VREKDKVLQEEQNKYDLLSQELQTQRQSFEVTINQLQNSNKSIQEQLLRKNILLDSASVS 690

Query: 211  XEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLE 270
             E  ++ + K +E  +    +  +E   L K +E +  +   L+E    L      + L+
Sbjct: 691  FEVNQKCLIKEKEEALEKIIKCNEEISHLKKTLEEQQFKNEDLQEKINDLRLQNENMLLQ 750

Query: 271  HSKLAQE-LEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIE 329
              KL  E LEQ                   I+    E  ++++    E+ N+ E   K  
Sbjct: 751  AEKLRSENLEQMRIFQDTQKS-----LNNRIDQLISENNKLQQ---TELLNLNERCDKFN 802

Query: 330  LLEHLNCQIRQTNKEL--ENKLATMG--TESKAVSSPSKKGSPLISRKSGRNTASKMKSP 385
            L+     Q++Q   +L  +N +      T S+ V    +    L+S+    +     +  
Sbjct: 803  LMFQ---QLQQEKLQLIQDNSIIVQDKITLSEKVRELQQNNIDLLSKIHNYDNQKNKEIV 859

Query: 386  WSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVD-KEYVISEKDTXXXXXXXXXXG 444
              +   + L    DK   +N +  LE  IQ    ++   KE +    ++           
Sbjct: 860  ELKYELDQLINQKDKLKQENHL--LEQEIQEYKNNINSYKEQI----NSFIVEINQFQLQ 913

Query: 445  KDTLIAQLQLEHQQHMEGPSLIHVGTNTEDV--------NEIAKVQEQLKQELNDEIKDV 496
             DTL  + +L+ +Q  +  +LI    N  D          E  ++ +   +EL DE    
Sbjct: 914  LDTLKQESRLKTEQIHQQENLILNQKNQIDTLVEKSYLDQESERLIDYKLKELEDEKIAC 973

Query: 497  NVK--DLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSN 554
            N K  + I+ L+  EEQ+  L+ +++  ++  +K+  ++K  L Q ++      +++  +
Sbjct: 974  NQKYENAIQNLRINEEQLRSLSIQLNQKSE-QVKILEDYKNVLTQEKE--QQLVEINKCH 1030

Query: 555  KEIVRLTEELHHLSQKVAELEEEKGNLQLHLVD-YDSGRMIESDVYKKMIEMENLAETRL 613
             +I +L+ EL    Q +  ++++  +LQ+ L    D    I+    +++IE + +    L
Sbjct: 1031 LQINKLSAELKEAEQSLQAVQDKCKDLQVSLNSASDQIFNIKQQYSQELIEKDQMI---L 1087

Query: 614  KAISLLESQKFDLVQELHILQQKYDEVEDKL---ADISQLQSDQVCSEIKSVHLEEQIDA 670
            +    L  Q  + +++  +L++   E+E +      +  L+ +    E++ + L +  + 
Sbjct: 1088 QCKEQLRYQCMNQIEQSQVLEEMTSEIEKQKNLEQQVQNLRKENEKLELEQIKLLKDNEI 1147

Query: 671  LSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAE 730
            L     +       ++L  E+    + +   + + + +KLQ   Q     T+K++ + ++
Sbjct: 1148 LRLHLIQKQPDNCQIELILEEHNQILTEYHEEIQRLKDKLQQKQQILEKFTNKIQ-IQSD 1206

Query: 731  KISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMED 790
            KI+E     N +E S +Q+ F  + K    +L IE  + ++ + + +    ++ I V+ +
Sbjct: 1207 KIAE-----NEKEISNLQS-FIANGKKHYENL-IEEYQLKMDQMQQQ--NTQQQI-VLNN 1256

Query: 791  RRYSLERKADQLGSYLQEKQKAYSEYT 817
            + + L +   Q+ S+L + QK  S+ T
Sbjct: 1257 QIHLLMQDKQQMKSHLDQIQKEMSDIT 1283


>UniRef50_A2EJ44 Cluster: Viral A-type inclusion protein, putative;
            n=1; Trichomonas vaginalis G3|Rep: Viral A-type inclusion
            protein, putative - Trichomonas vaginalis G3
          Length = 676

 Score =  123 bits (296), Expect = 5e-26
 Identities = 142/705 (20%), Positives = 323/705 (45%), Gaps = 59/705 (8%)

Query: 616  ISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASK 675
            + L++ +  +L Q+L  +  + D +++  + +S  + +++  ++++ + +E+I+ L+   
Sbjct: 12   LELMDQENTELKQKLDEITSERDNLKNSNSQLSA-EIEELKKKVETENNDEEINELTEEI 70

Query: 676  KELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISEL 735
            + L+  +E  K   E L    K++E  K+D  NK++  + E+    +       E ISEL
Sbjct: 71   ESLSAELEQEKTKNENLN---KEIETLKQDYENKIKE-LSESSKSKESGHSDDGEVISEL 126

Query: 736  LAKINH--EEQSKIQTQ-FGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRR 792
              +IN   EE  K ++    ++A +QE +  + +   E +  + +I  L E+I  +++  
Sbjct: 127  EDEINRLKEELDKSKSHNTELEAILQENEEKLNSKSQESTDSEQKIKELTETIQSLQNSN 186

Query: 793  YSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQ 852
              ++   D L + +++ +K  ++   ++D++   L+ +    + ++ ++   + EN+E+Q
Sbjct: 187  TEMQNSQDDLKNQIEKLKKIINQ---KDDDISKHLSDI----QALQTEIENSDKENQEIQ 239

Query: 853  KKNQILLEE----NQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLK 908
            ++ Q L++E    NQ L   L + Q++Y  L  ++N   + ++E  +   +L   ES++ 
Sbjct: 240  QEKQKLIDELNEKNQQLTDQLKESQENYEKLKSESNDEKVGQNELNE---KLLAAESDIN 296

Query: 909  RITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYK 968
             +  +    I    ++I     E+N+QI      +KV  +KY+ + + +T  +A+L +  
Sbjct: 297  DLKSQ----IESNNQQIS----EYNSQISEL--QQKV--DKYKVSNDQLTASQAELSQ-- 342

Query: 969  NNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIAL 1028
              +E+    +E+L   N E   + +   Q+ +    E  + +++ L++ + + +   +AL
Sbjct: 343  -KLEDSTSEIEKLKSENNEK-SQAITDLQSSNNTNNENLLKQLDLLSSKISELENSSLAL 400

Query: 1029 NQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQL--------LDSKQHNEE 1080
              + N      +  +    SKL +    L N + ++Q+ + ++        L +     +
Sbjct: 401  KSE-NKTLTEQIGSLDHENSKLKRDFEVLSNEKSKLQKENDKVKADIEQLSLSNSDEIGK 459

Query: 1081 LQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXX 1140
            L  L++ +D+QI EL++       N  K E       I+  +++  N +           
Sbjct: 460  LNDLIQSKDNQISELQKENDENMTNKAKLE-----EEIKRSAEEIENKEKEIESLNSQLE 514

Query: 1141 XLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLK 1200
             LK   EE    ++  L E    +N ++ +  + I + E +  E        Q +I+ L 
Sbjct: 515  NLKKSMEESEEGDKKTLVE----MNQKISDLNSMISENEKIIEEKQSEIDQKQSEIDSLS 570

Query: 1201 SKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELW---KQHLAQREADFQKTEHEL 1257
             + + L  + D +     + +S + S  +    E+ EL    +Q  +Q E   +K   E+
Sbjct: 571  HENQDLQQKLDEMKQNYEDEKSKLISEKESVDHELNELKNKSEQEKSQNEEKIEKLNKEI 630

Query: 1258 RVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDK 1302
                   E   +Q  D   +  QE+ N+I  + + TS + K + K
Sbjct: 631  EEINKQNEELSKQNNDEFSNLIQEKNNEINKLNEETSRKRKKKKK 675



 Score =  120 bits (290), Expect = 3e-25
 Identities = 153/702 (21%), Positives = 298/702 (42%), Gaps = 54/702 (7%)

Query: 834  DRVVE--KQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAES 891
            D + E  +QL  ++ EN EL++K   +  E  NL+ S S +      L +K   T+  + 
Sbjct: 3    DEIAELTEQLELMDQENTELKQKLDEITSERDNLKNSNSQLSAEIEELKKKVE-TENNDE 61

Query: 892  ESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYE 951
            E  +   ++  L + L++   +++ L     KEIE L+ ++  +I+      K     + 
Sbjct: 62   EINELTEEIESLSAELEQEKTKNENL----NKEIETLKQDYENKIKELSESSKSKESGHS 117

Query: 952  KNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEI 1011
             + E +++LE ++   K  ++    +  EL  +  E  +K   K Q +S D +EQ I E+
Sbjct: 118  DDGEVISELEDEINRLKEELDKSKSHNTELEAILQENEEKLNSKSQ-ESTD-SEQKIKEL 175

Query: 1012 NKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQL 1071
             +    L+  + E+      + N       +++  +  +++  + ++ ++ E++   K+ 
Sbjct: 176  TETIQSLQNSNTEMQNSQDDLKNQIEKLKKIINQKDDDISKHLSDIQALQTEIENSDKEN 235

Query: 1072 LDSKQHNEELQILVREQDDQIKE-LKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDX 1130
             + +Q  ++L   + E++ Q+ + LKE++  +E    K+E     S  E +    N ++ 
Sbjct: 236  QEIQQEKQKLIDELNEKNQQLTDQLKESQENYEKL--KSE-----SNDEKVGQ--NELNE 286

Query: 1131 XXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDV 1190
                       LK Q E           +Q ++ N+++ E   K+ + +  N +LT    
Sbjct: 287  KLLAAESDINDLKSQIESN--------NQQISEYNSQISELQQKVDKYKVSNDQLTASQA 338

Query: 1191 VNQEQINQLKSKLEQLNTENDNLLSTVAELRSS-------ISSAVDQRGFEIAELWKQHL 1243
               +++    S++E+L +EN+     + +L+SS       +   +D    +I+EL    L
Sbjct: 339  ELSQKLEDSTSEIEKLKSENNEKSQAITDLQSSNNTNNENLLKQLDLLSSKISELENSSL 398

Query: 1244 AQREADFQKTEH--ELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQD 1301
            A +  +   TE    L  + S  +  +E +L + +S  Q+E +K+    +  SL N    
Sbjct: 399  ALKSENKTLTEQIGSLDHENSKLKRDFE-VLSNEKSKLQKENDKVKADIEQLSLSN---- 453

Query: 1302 KEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQ 1361
              + +  L +      NQI  L+ E  DE +                  +   E +S   
Sbjct: 454  -SDEIGKLNDLIQSKDNQISELQKE-NDENMTNKAKLEEEIKRSAEEIENKEKEIESLNS 511

Query: 1362 MQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTH 1421
              E    ++ E     KK+              +++ E  + E   +++ K SEI   +H
Sbjct: 512  QLENLKKSMEESEEGDKKTLVEMNQKISDLNSMISENEKIIEEKQSEIDQKQSEIDSLSH 571

Query: 1422 EYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESE 1481
            E    L Q+ DE +        YE     L  EKES      L   +N +  E  Q E +
Sbjct: 572  E-NQDLQQKLDEMKQ------NYEDEKSKLISEKES--VDHELNELKNKSEQEKSQNEEK 622

Query: 1482 IERV-KLIEELNVKITE-SVSLNKQVAELNKALEEEVAKTNE 1521
            IE++ K IEE+N +  E S   N + + L +    E+ K NE
Sbjct: 623  IEKLNKEIEEINKQNEELSKQNNDEFSNLIQEKNNEINKLNE 664



 Score =  118 bits (285), Expect = 1e-24
 Identities = 144/662 (21%), Positives = 306/662 (46%), Gaps = 54/662 (8%)

Query: 699  LENDKEDIMNKLQNYIQENMDLTDKLEKMSAEK------ISELLAKINHEEQSKIQTQFG 752
            ++++  ++  +L+   QEN +L  KL+++++E+       S+L A+I  E + K++T+  
Sbjct: 1    MDDEIAELTEQLELMDQENTELKQKLDEITSERDNLKNSNSQLSAEI-EELKKKVETE-N 58

Query: 753  IDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKA 812
             D +I E    IE++ +EL + K++   L + I   E  +   E K  +L    + K+  
Sbjct: 59   NDEEINELTEEIESLSAELEQEKTKNENLNKEI---ETLKQDYENKIKELSESSKSKESG 115

Query: 813  YS---EYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKE-LQKKNQILLEENQNLQIS 868
            +S   E   + ++ +NRL   +D  +    +L  I  EN+E L  K+Q   +  Q ++  
Sbjct: 116  HSDDGEVISELEDEINRLKEELDKSKSHNTELEAILQENEEKLNSKSQESTDSEQKIKEL 175

Query: 869  LSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDL 928
               +Q   N+  E  N  D  +++  K +  +   + ++ +   + Q L    + EIE+ 
Sbjct: 176  TETIQSLQNSNTEMQNSQDDLKNQIEKLKKIINQKDDDISKHLSDIQAL----QTEIENS 231

Query: 929  EIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLEL 988
            + E N +I+     +K+++E  EKN +   QL+   + Y+      N      N++N +L
Sbjct: 232  DKE-NQEIQQ--EKQKLIDELNEKNQQLTDQLKESQENYEKLKSESNDEKVGQNELNEKL 288

Query: 989  IDKHVQKQQTQSP-DYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYE 1047
            +         +S  +   Q I+E N   + L+QK ++    N ++  +Q      + D  
Sbjct: 289  LAAESDINDLKSQIESNNQQISEYNSQISELQQKVDKYKVSNDQLTASQAELSQKLEDST 348

Query: 1048 SKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIP 1107
            S++ +   K EN  E+ Q ++     +  +NE L   +     +I EL+ + L       
Sbjct: 349  SEIEKL--KSEN-NEKSQAITDLQSSNNTNNENLLKQLDLLSSKISELENSSLAL----- 400

Query: 1108 KTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQ---ERSVL--QEQSA 1162
            K+E   ++  I  +  D  N               K+Q+E + ++   E+  L   ++  
Sbjct: 401  KSENKTLTEQIGSL--DHENSKLKRDFEVLSNEKSKLQKENDKVKADIEQLSLSNSDEIG 458

Query: 1163 KLNTELQECYTKIIQLETLNTE-LTGHDVVNQ------EQINQLKSKLEQLNTENDNLLS 1215
            KLN  +Q    +I +L+  N E +T    + +      E+I   + ++E LN++ +NL  
Sbjct: 459  KLNDLIQSKDNQISELQKENDENMTNKAKLEEEIKRSAEEIENKEKEIESLNSQLENLKK 518

Query: 1216 TVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFES------KYE 1269
            ++ E        + +   +I++L    +++ E   ++ + E+  + S  +S        +
Sbjct: 519  SMEESEEGDKKTLVEMNQKISDL-NSMISENEKIIEEKQSEIDQKQSEIDSLSHENQDLQ 577

Query: 1270 QLLDSVQSSTQEETNKIVT-MEQVTSLQNKLQDKEEHLRNLQEKYADVIN-QIEILRSEI 1327
            Q LD ++ + ++E +K+++  E V    N+L++K E  ++  E+  + +N +IE +  + 
Sbjct: 578  QKLDEMKQNYEDEKSKLISEKESVDHELNELKNKSEQEKSQNEEKIEKLNKEIEEINKQN 637

Query: 1328 ED 1329
            E+
Sbjct: 638  EE 639



 Score =  113 bits (271), Expect = 5e-23
 Identities = 159/711 (22%), Positives = 326/711 (45%), Gaps = 62/711 (8%)

Query: 556  EIVRLTEELHHLSQKVAELEEEKGNLQL---HLVDYDSGRMIESDVYKKMIEMENLAETR 612
            EI  LTE+L  + Q+  EL+++   +     +L + +S    E +  KK +E EN  E  
Sbjct: 4    EIAELTEQLELMDQENTELKQKLDEITSERDNLKNSNSQLSAEIEELKKKVETENNDEEI 63

Query: 613  LKAISLLESQKFDLVQELHILQQKYDEVEDKLADI-SQLQSDQVCSEIKSVHLEEQIDAL 671
             +    +ES   +L QE    +    E+E    D  ++++     S+ K     +  + +
Sbjct: 64   NELTEEIESLSAELEQEKTKNENLNKEIETLKQDYENKIKELSESSKSKESGHSDDGEVI 123

Query: 672  SASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEK 731
            S  + E+  + E  +LDK + + T  +LE   ++   KL +  QE+ D   K+++++ E 
Sbjct: 124  SELEDEINRLKE--ELDKSKSHNT--ELEAILQENEEKLNSKSQESTDSEQKIKELT-ET 178

Query: 732  ISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDR 791
            I + L   N E Q+   +Q  +  +I++    I   + ++SK+ S I  L+  I   +  
Sbjct: 179  I-QSLQNSNTEMQN---SQDDLKNQIEKLKKIINQKDDDISKHLSDIQALQTEIENSDKE 234

Query: 792  RYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLE--IEHENK 849
               ++++  +L   L EK +  ++   +  E   +L    + ++V + +L E  +  E+ 
Sbjct: 235  NQEIQQEKQKLIDELNEKNQQLTDQLKESQENYEKLKSESNDEKVGQNELNEKLLAAESD 294

Query: 850  ELQKKNQILLEENQNLQIS-----LSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLE 904
                K+QI   E+ N QIS     +S++QQ  +    K +   L  S++   Q +L D  
Sbjct: 295  INDLKSQI---ESNNQQISEYNSQISELQQKVDKY--KVSNDQLTASQAELSQ-KLEDST 348

Query: 905  SNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQL 964
            S ++++  E+     +K + I DL+   NT  E+ ++   +L+ K  +       L+++ 
Sbjct: 349  SEIEKLKSENN----EKSQAITDLQSSNNTNNENLLKQLDLLSSKISELENSSLALKSEN 404

Query: 965  QEYKNNIENLNMNVEELNKMNLELIDKH---VQKQQTQSPDYTEQY----INEINKLNAL 1017
            +     I +L+    +L K + E++      +QK+  +     EQ      +EI KLN L
Sbjct: 405  KTLTEQIGSLDHENSKL-KRDFEVLSNEKSKLQKENDKVKADIEQLSLSNSDEIGKLNDL 463

Query: 1018 LKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQH 1077
            ++ KD +I  L QK N+     M+  +  E ++ +   ++EN E+E++ ++ QL + K+ 
Sbjct: 464  IQSKDNQISEL-QKENDEN---MTNKAKLEEEIKRSAEEIENKEKEIESLNSQLENLKKS 519

Query: 1078 NEELQILVREQDDQIKELKETKLTFEMNIPKTEG-MIISSTIEPMSDDANNVDXXXXXXX 1136
             EE      E+ D+   ++  +   ++N   +E   II      +    + +D       
Sbjct: 520  MEE-----SEEGDKKTLVEMNQKISDLNSMISENEKIIEEKQSEIDQKQSEIDSLSHENQ 574

Query: 1137 XXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQI 1196
                 L  + ++ +  E+S L  +   ++ EL E   K  Q ++           N+E+I
Sbjct: 575  DLQQKLD-EMKQNYEDEKSKLISEKESVDHELNELKNKSEQEKS----------QNEEKI 623

Query: 1197 NQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQRE 1247
             +L  ++E++N +N+ L     +     S+ + ++  EI +L ++   +R+
Sbjct: 624  EKLNKEIEEINKQNEELSK---QNNDEFSNLIQEKNNEINKLNEETSRKRK 671



 Score =  109 bits (262), Expect = 6e-22
 Identities = 141/647 (21%), Positives = 293/647 (45%), Gaps = 53/647 (8%)

Query: 495  DVNVKDLIEKLKSAEEQITQLN---DEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVS 551
            D  + +L E+L+  +++ T+L    DEI +   N+    S    ++++++K ++      
Sbjct: 2    DDEIAELTEQLELMDQENTELKQKLDEITSERDNLKNSNSQLSAEIEELKKKVET----E 57

Query: 552  DSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAET 611
            ++++EI  LTEE+  LS   AELE+EK   +    + ++ +    +  K++ E     E+
Sbjct: 58   NNDEEINELTEEIESLS---AELEQEKTKNENLNKEIETLKQDYENKIKELSESSKSKES 114

Query: 612  RL----KAISLLESQKFDLVQELHILQQKYDEVEDKLAD----ISQLQSDQVCSEIKSVH 663
                  + IS LE +   L +EL   +    E+E  L +    ++    +   SE K   
Sbjct: 115  GHSDDGEVISELEDEINRLKEELDKSKSHNTELEAILQENEEKLNSKSQESTDSEQKIKE 174

Query: 664  LEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDK 723
            L E I +L  S  E+    ++LK   E+L   I   ++D    ++ +Q  +Q  ++ +DK
Sbjct: 175  LTETIQSLQNSNTEMQNSQDDLKNQIEKLKKIINQKDDDISKHLSDIQ-ALQTEIENSDK 233

Query: 724  LEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEE 783
              +   ++  +L+ ++N + Q        +  +++E     E ++SE +  K     L E
Sbjct: 234  ENQEIQQEKQKLIDELNEKNQQ-------LTDQLKESQENYEKLKSESNDEKVGQNELNE 286

Query: 784  SIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRL-AVLMDHDRVVEKQLL 842
             +        + E   + L S ++   +  SEY  Q  EL  ++    + +D++   Q  
Sbjct: 287  KL-------LAAESDINDLKSQIESNNQQISEYNSQISELQQKVDKYKVSNDQLTASQ-A 338

Query: 843  EIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEK-ANRTDLAESESTKYQTQLR 901
            E+  + ++   + + L  EN     +++D+Q   N   E    + DL  S+ ++ +    
Sbjct: 339  ELSQKLEDSTSEIEKLKSENNEKSQAITDLQSSNNTNNENLLKQLDLLSSKISELENSSL 398

Query: 902  DLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKV---LNEKYEKNIEYVT 958
             L+S  K +T +  +L  +  K   D E+  N + +    + KV   + +    N + + 
Sbjct: 399  ALKSENKTLTEQIGSLDHENSKLKRDFEVLSNEKSKLQKENDKVKADIEQLSLSNSDEIG 458

Query: 959  QLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALL 1018
            +L   +Q   N I  L    +E N  N   +++ + K+  +  +  E+ I  +N     L
Sbjct: 459  KLNDLIQSKDNQISELQKENDE-NMTNKAKLEEEI-KRSAEEIENKEKEIESLNSQLENL 516

Query: 1019 KQKDEE--------IIALNQKIN--NAQVS-YMSMVSDYESKLAQFTTKLENMEEEMQRV 1067
            K+  EE        ++ +NQKI+  N+ +S    ++ + +S++ Q  ++++++  E Q +
Sbjct: 517  KKSMEESEEGDKKTLVEMNQKISDLNSMISENEKIIEEKQSEIDQKQSEIDSLSHENQDL 576

Query: 1068 SKQLLDSKQ-HNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMI 1113
             ++L + KQ + +E   L+ E++    EL E K   E    + E  I
Sbjct: 577  QQKLDEMKQNYEDEKSKLISEKESVDHELNELKNKSEQEKSQNEEKI 623



 Score =  109 bits (261), Expect = 8e-22
 Identities = 144/697 (20%), Positives = 291/697 (41%), Gaps = 59/697 (8%)

Query: 879  LVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIES 938
            + E   + +L + E+T+ + +L ++ S    + + +  L      EIE+L+     ++E+
Sbjct: 5    IAELTEQLELMDQENTELKQKLDEITSERDNLKNSNSQL----SAEIEELK----KKVET 56

Query: 939  AIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEEL-----NKMNLELIDKHV 993
               D+++ NE  E+    +  L A+L++ K   ENLN  +E L     NK+  EL +   
Sbjct: 57   ENNDEEI-NELTEE----IESLSAELEQEKTKNENLNKEIETLKQDYENKIK-ELSESSK 110

Query: 994  QKQQTQSPD--YTEQYINEINKLNALL---KQKDEEIIALNQKINNAQVSYMSMVSDYES 1048
             K+   S D     +  +EIN+L   L   K  + E+ A+ Q+      S     +D E 
Sbjct: 111  SKESGHSDDGEVISELEDEINRLKEELDKSKSHNTELEAILQENEEKLNSKSQESTDSEQ 170

Query: 1049 KLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQI-KELKETK-LTFEMNI 1106
            K+ + T  +++++     +     D K   E+L+ ++ ++DD I K L + + L  E+  
Sbjct: 171  KIKELTETIQSLQNSNTEMQNSQDDLKNQIEKLKKIINQKDDDISKHLSDIQALQTEIEN 230

Query: 1107 PKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNT 1166
               E   I    + + D+ N  +               + + E   E+    E + KL  
Sbjct: 231  SDKENQEIQQEKQKLIDELNEKNQQLTDQLKESQENYEKLKSESNDEKVGQNELNEKLLA 290

Query: 1167 ELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISS 1226
               +      Q+E+ N +++ ++     QI++L+ K+++    ND L ++ AEL   +  
Sbjct: 291  AESDINDLKSQIESNNQQISEYN----SQISELQQKVDKYKVSNDQLTASQAELSQKLED 346

Query: 1227 AVDQRGFEIAELWKQHLAQREADFQKTEH----ELRVQLSAFESKYEQLLDSVQSSTQEE 1282
            +  +   E  +      +Q   D Q + +     L  QL    SK  +L +S  S   + 
Sbjct: 347  STSE--IEKLKSENNEKSQAITDLQSSNNTNNENLLKQLDLLSSKISELENS--SLALKS 402

Query: 1283 TNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXX 1342
             NK +T EQ+ SL ++    +     L  + + +  + + ++++IE   ++         
Sbjct: 403  ENKTLT-EQIGSLDHENSKLKRDFEVLSNEKSKLQKENDKVKADIEQLSLS--------- 452

Query: 1343 XXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKV 1402
                    D   +     Q ++  I  + +EN +   +              + + E ++
Sbjct: 453  ------NSDEIGKLNDLIQSKDNQISELQKENDENMTNKAKLEEEIKRSAEEIENKEKEI 506

Query: 1403 LELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYE---KESEL 1459
              L  QLE     + +       TL + N +  ++   + E EK IE+   E   K+SE+
Sbjct: 507  ESLNSQLENLKKSMEESEEGDKKTLVEMNQKISDLNSMISENEKIIEEKQSEIDQKQSEI 566

Query: 1460 AILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKT 1519
              L  +  +     + M++  E E+ KLI E      E   L  +  +     EE++ K 
Sbjct: 567  DSLSHENQDLQQKLDEMKQNYEDEKSKLISEKESVDHELNELKNKSEQEKSQNEEKIEKL 626

Query: 1520 NEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQK 1556
            N+    +  Q  E+   N++     N+++  +++I K
Sbjct: 627  NKEIEEINKQNEELSKQNND--EFSNLIQEKNNEINK 661



 Score =  107 bits (257), Expect = 2e-21
 Identities = 151/714 (21%), Positives = 311/714 (43%), Gaps = 62/714 (8%)

Query: 321  MTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTAS 380
            + ELT+++EL++  N +++Q   E+ ++   +   +  +S+  ++    +  ++     +
Sbjct: 5    IAELTEQLELMDQENTELKQKLDEITSERDNLKNSNSQLSAEIEELKKKVETENNDEEIN 64

Query: 381  KMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXX 440
            ++      LS+E L Q+  K  N N+       I++L +D  +K   I E          
Sbjct: 65   ELTEEIESLSAE-LEQEKTKNENLNK------EIETLKQDYENK---IKELSESSKSKES 114

Query: 441  XXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVN--V 498
                   +I++L+ E  +  E   L    ++  ++  I +  E+     + E  D    +
Sbjct: 115  GHSDDGEVISELEDEINRLKE--ELDKSKSHNTELEAILQENEEKLNSKSQESTDSEQKI 172

Query: 499  KDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIV 558
            K+L E ++S +   T++ +  D     + K+K     K   + K + +   +    +   
Sbjct: 173  KELTETIQSLQNSNTEMQNSQDDLKNQIEKLKKIINQKDDDISKHLSDIQALQTEIENSD 232

Query: 559  RLTEELHHLSQK-VAELEEEKGNLQLHLVD-YDSGRMIESDVYKKMIEMENLAETRLKAI 616
            +  +E+    QK + EL E+   L   L +  ++   ++S+   + +    L E  L A 
Sbjct: 233  KENQEIQQEKQKLIDELNEKNQQLTDQLKESQENYEKLKSESNDEKVGQNELNEKLLAA- 291

Query: 617  SLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKK 676
               ES   DL  ++    Q+  E   +++++ Q       S           D L+AS+ 
Sbjct: 292  ---ESDINDLKSQIESNNQQISEYNSQISELQQKVDKYKVSN----------DQLTASQA 338

Query: 677  ELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELL 736
            EL+  +E+   + E+L    K   N+K   +  LQ+    N +   K   + + KISEL 
Sbjct: 339  ELSQKLEDSTSEIEKL----KSENNEKSQAITDLQSSNNTNNENLLKQLDLLSSKISELE 394

Query: 737  -AKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESI-AVMEDRRYS 794
             + +  + ++K  T+  I +   E      + E  LS  KS++ +  + + A +E    S
Sbjct: 395  NSSLALKSENKTLTE-QIGSLDHENSKLKRDFEV-LSNEKSKLQKENDKVKADIEQLSLS 452

Query: 795  LERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKK 854
               +  +L   +Q K    SE   + DE +   A L +    +++   EIE++ KE++  
Sbjct: 453  NSDEIGKLNDLIQSKDNQISELQKENDENMTNKAKLEEE---IKRSAEEIENKEKEIESL 509

Query: 855  NQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKY----QTQLRDLESNLKRI 910
            N  L    ++++ S    ++    + +K +  +   SE+ K     Q+++   +S +  +
Sbjct: 510  NSQLENLKKSMEESEEGDKKTLVEMNQKISDLNSMISENEKIIEEKQSEIDQKQSEIDSL 569

Query: 911  THEHQTL---IVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEY 967
            +HE+Q L   + + K+  ED + +  ++ ES   +   LNE   K+ +  +Q E ++++ 
Sbjct: 570  SHENQDLQQKLDEMKQNYEDEKSKLISEKESVDHE---LNELKNKSEQEKSQNEEKIEKL 626

Query: 968  KNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQK 1021
               IE +N   EEL+K N +     +Q++            NEINKLN    +K
Sbjct: 627  NKEIEEINKQNEELSKQNNDEFSNLIQEKN-----------NEINKLNEETSRK 669



 Score = 96.3 bits (229), Expect = 6e-18
 Identities = 131/672 (19%), Positives = 287/672 (42%), Gaps = 60/672 (8%)

Query: 946  LNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTE 1005
            L E+ E   +  T+L+ +L E  +  +NL  +  +L+   +E + K V+ +     +   
Sbjct: 8    LTEQLELMDQENTELKQKLDEITSERDNLKNSNSQLSA-EIEELKKKVETENND--EEIN 64

Query: 1006 QYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDY-------ESKLAQFTTKLE 1058
            +   EI  L+A L+Q+  +   LN++I   +  Y + + +        ES  +     + 
Sbjct: 65   ELTEEIESLSAELEQEKTKNENLNKEIETLKQDYENKIKELSESSKSKESGHSDDGEVIS 124

Query: 1059 NMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTI 1118
             +E+E+ R+ ++L  SK HN EL+ +++E ++++    +     E  I +    I S  +
Sbjct: 125  ELEDEINRLKEELDKSKSHNTELEAILQENEEKLNSKSQESTDSEQKIKELTETIQS--L 182

Query: 1119 EPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQ------EQSAKLNTELQECY 1172
            +  + +  N              +  Q++++  +  S +Q      E S K N E+Q+  
Sbjct: 183  QNSNTEMQNSQDDLKNQIEKLKKIINQKDDDISKHLSDIQALQTEIENSDKENQEIQQEK 242

Query: 1173 TKII-QLETLNTELTGHDVVNQEQINQLKSKLEQ----LNTENDNLLSTVAELRSSISSA 1227
             K+I +L   N +LT     +QE   +LKS+        N  N+ LL+  +++ + + S 
Sbjct: 243  QKLIDELNEKNQQLTDQLKESQENYEKLKSESNDEKVGQNELNEKLLAAESDI-NDLKSQ 301

Query: 1228 VDQRGFEIAELWKQ--HLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNK 1285
            ++    +I+E   Q   L Q+   ++ +  +L    +    K E     ++    E   K
Sbjct: 302  IESNNQQISEYNSQISELQQKVDKYKVSNDQLTASQAELSQKLEDSTSEIEKLKSENNEK 361

Query: 1286 IVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXX 1345
                + +T LQ+      E+L          + Q+++L S+I + + +            
Sbjct: 362  ---SQAITDLQSSNNTNNENL----------LKQLDLLSSKISELENS-SLALKSENKTL 407

Query: 1346 XXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLEL 1405
                  L  EN   K+  E     ++ E ++L+K +              +D   K+ +L
Sbjct: 408  TEQIGSLDHENSKLKRDFEV----LSNEKSKLQKENDKVKADIEQLSLSNSDEIGKLNDL 463

Query: 1406 THQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKES-ELAILRL 1464
                + + SE+ ++  E      +  +E +   +++   EK IE L  + E+ + ++   
Sbjct: 464  IQSKDNQISELQKENDENMTNKAKLEEEIKRSAEEIENKEKEIESLNSQLENLKKSMEES 523

Query: 1465 KMHENANHYETMQKESEI-----ERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKT 1519
            +  +     E  QK S++     E  K+IEE   +I +  S    ++  N+ L++   K 
Sbjct: 524  EEGDKKTLVEMNQKISDLNSMISENEKIIEEKQSEIDQKQSEIDSLSHENQDLQQ---KL 580

Query: 1520 NEMQTALENQEIEIVT----LNDEITNLQNMVRASSSKIQKHVSFAS---DTKQGRDEQL 1572
            +EM+   E+++ ++++    ++ E+  L+N      S+ ++ +   +   +    ++E+L
Sbjct: 581  DEMKQNYEDEKSKLISEKESVDHELNELKNKSEQEKSQNEEKIEKLNKEIEEINKQNEEL 640

Query: 1573 DNTMNKELLDAV 1584
                N E  + +
Sbjct: 641  SKQNNDEFSNLI 652



 Score = 94.3 bits (224), Expect = 2e-17
 Identities = 141/701 (20%), Positives = 293/701 (41%), Gaps = 53/701 (7%)

Query: 778  ICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVV 837
            I  L E + +M+     L++K D++ S     + + S+ + + +EL  ++    ++D  +
Sbjct: 5    IAELTEQLELMDQENTELKQKLDEITSERDNLKNSNSQLSAEIEELKKKVET-ENNDEEI 63

Query: 838  EKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQ 897
             +   EIE  + EL+++      +N+NL   +  ++Q Y   ++     +L+ES  +K  
Sbjct: 64   NELTEEIESLSAELEQEKT----KNENLNKEIETLKQDYENKIK-----ELSESSKSKES 114

Query: 898  TQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYV 957
                D E     +  E +  I + K+E+ D     NT++E+ +++ +   EK     +  
Sbjct: 115  GHSDDGE-----VISELEDEINRLKEEL-DKSKSHNTELEAILQENE---EKLNSKSQES 165

Query: 958  TQLEAQLQEYKNNIENL-NMNVEELNKMN-LELIDKHVQKQQTQSPDYTEQYINEINKLN 1015
            T  E +++E    I++L N N E  N  + L+   + ++K   Q  D   +++++I  L 
Sbjct: 166  TDSEQKIKELTETIQSLQNSNTEMQNSQDDLKNQIEKLKKIINQKDDDISKHLSDIQALQ 225

Query: 1016 ALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSK 1075
              ++  D+E    NQ+I   Q     ++ +   K  Q T +L+  +E  +++  +  D K
Sbjct: 226  TEIENSDKE----NQEI---QQEKQKLIDELNEKNQQLTDQLKESQENYEKLKSESNDEK 278

Query: 1076 QHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMI--ISSTIEP--MSDD---ANNV 1128
                EL   +   +  I +LK    +    I +    I  +   ++   +S+D   A+  
Sbjct: 279  VGQNELNEKLLAAESDINDLKSQIESNNQQISEYNSQISELQQKVDKYKVSNDQLTASQA 338

Query: 1129 DXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTE-----LQECYTKIIQLETLNT 1183
            +             K++ E     +     + S   N E     L    +KI +LE  + 
Sbjct: 339  ELSQKLEDSTSEIEKLKSENNEKSQAITDLQSSNNTNNENLLKQLDLLSSKISELENSSL 398

Query: 1184 ELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSS---ISSAVDQRGFEIA-ELW 1239
             L   +    EQI  L  +  +L  + + L +  ++L+     + + ++Q     + E+ 
Sbjct: 399  ALKSENKTLTEQIGSLDHENSKLKRDFEVLSNEKSKLQKENDKVKADIEQLSLSNSDEIG 458

Query: 1240 KQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTS-LQNK 1298
            K +   +  D Q +E  L+ +     +   +L + ++ S +E  NK   +E + S L+N 
Sbjct: 459  KLNDLIQSKDNQISE--LQKENDENMTNKAKLEEEIKRSAEEIENKEKEIESLNSQLENL 516

Query: 1299 LQDKEEHLRNLQEKYADVINQIEILRSEI-EDEKVAFXXXXXXXXXXXXXXXXDLRTENQ 1357
             +  EE     ++   ++  +I  L S I E+EK+                   L  ENQ
Sbjct: 517  KKSMEESEEGDKKTLVEMNQKISDLNSMISENEKII--EEKQSEIDQKQSEIDSLSHENQ 574

Query: 1358 SYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIY 1417
              +Q  ++   N  +E ++L                +    +++  E   +L  +  EI 
Sbjct: 575  DLQQKLDEMKQNYEDEKSKLISEKESVDHELNELKNKSEQEKSQNEEKIEKLNKEIEEIN 634

Query: 1418 QKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESE 1458
            ++  E +    Q NDEF N+ Q+      ++ + T  K  +
Sbjct: 635  KQNEELS---KQNNDEFSNLIQEKNNEINKLNEETSRKRKK 672



 Score = 69.3 bits (162), Expect = 8e-10
 Identities = 87/398 (21%), Positives = 180/398 (45%), Gaps = 31/398 (7%)

Query: 1194 EQINQLKSKLEQLNTENDNLLSTVAEL---RSSISSAVDQRGFEIAELWKQHLAQREADF 1250
            ++I +L  +LE ++ EN  L   + E+   R ++ ++  Q   EI EL K+   + E + 
Sbjct: 3    DEIAELTEQLELMDQENTELKQKLDEITSERDNLKNSNSQLSAEIEELKKK--VETENND 60

Query: 1251 QKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNK-IVTMEQVTSLQNKLQDKEEHLRNL 1309
            ++  +EL  ++ +  ++ EQ     + +  E  NK I T++Q    +NK+++  E  ++ 
Sbjct: 61   EEI-NELTEEIESLSAELEQ-----EKTKNENLNKEIETLKQ--DYENKIKELSESSKSK 112

Query: 1310 QEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILN 1369
            +  ++D     E++ SE+EDE                     L+ EN+     + Q   +
Sbjct: 113  ESGHSD---DGEVI-SELEDEINRLKEELDKSKSHNTELEAILQ-ENEEKLNSKSQESTD 167

Query: 1370 INEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQ 1429
              ++  +L ++               +D + ++ +L   +  KD +I +   +     T+
Sbjct: 168  SEQKIKELTETIQSLQNSNTEMQNSQDDLKNQIEKLKKIINQKDDDISKHLSDIQALQTE 227

Query: 1430 -RNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLI 1488
              N + EN  Q++ + ++++ D   EK  +L     ++ E+  +YE ++ ES  E+V   
Sbjct: 228  IENSDKEN--QEIQQEKQKLIDELNEKNQQLTD---QLKESQENYEKLKSESNDEKVGQ- 281

Query: 1489 EELNVKITESVS----LNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQ 1544
             ELN K+  + S    L  Q+   N+ + E  ++ +E+Q  ++  ++    L      L 
Sbjct: 282  NELNEKLLAAESDINDLKSQIESNNQQISEYNSQISELQQKVDKYKVSNDQLTASQAELS 341

Query: 1545 NMVRASSSKIQKHVSFASDTKQG-RDEQLDNTMNKELL 1581
              +  S+S+I+K  S  ++  Q   D Q  N  N E L
Sbjct: 342  QKLEDSTSEIEKLKSENNEKSQAITDLQSSNNTNNENL 379



 Score = 67.7 bits (158), Expect = 2e-09
 Identities = 109/536 (20%), Positives = 231/536 (43%), Gaps = 63/536 (11%)

Query: 144 VTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXX 203
           +  L+ TI+   N+ + +Q     ++  I  L++ IN+KD  I                 
Sbjct: 172 IKELTETIQSLQNSNTEMQNSQDDLKNQIEKLKKIINQKDDDI----------------- 214

Query: 204 XXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRIS-SLEEANKLLEA 262
                    D +   T++ EN      E + EKQ+L+ ++  K+ +++  L+E+ +  E 
Sbjct: 215 ----SKHLSDIQALQTEI-ENSDKENQEIQQEKQKLIDELNEKNQQLTDQLKESQENYEK 269

Query: 263 ARFEISLEHSKLAQ-ELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANM 321
            + E + E  K+ Q EL +                K  IE + ++ +E         + +
Sbjct: 270 LKSESNDE--KVGQNELNEKLLAAESDIND----LKSQIESNNQQISEYN-------SQI 316

Query: 322 TELTKKIELLEHLNCQIRQTNKELENKLATMGTE-SKAVSSPSKKGSPLISRKSGRNTAS 380
           +EL +K++  +  N Q+  +  EL  KL    +E  K  S  ++K   +   +S  NT +
Sbjct: 317 SELQQKVDKYKVSNDQLTASQAELSQKLEDSTSEIEKLKSENNEKSQAITDLQSSNNTNN 376

Query: 381 K--------MKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKD 432
           +        + S  S+L + +L   ++ K    +I  L+     L +D    E + +EK 
Sbjct: 377 ENLLKQLDLLSSKISELENSSLALKSENKTLTEQIGSLDHENSKLKRDF---EVLSNEKS 433

Query: 433 TXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDE 492
                           I QL L +   +     ++    ++D N+I+++Q++  + + ++
Sbjct: 434 KLQKENDKVKAD----IEQLSLSNSDEI---GKLNDLIQSKD-NQISELQKENDENMTNK 485

Query: 493 IK-DVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQM-QKTIDNFSKV 550
            K +  +K   E++++ E++I  LN +++   K+M + +   K  L +M QK  D  S +
Sbjct: 486 AKLEEEIKRSAEEIENKEKEIESLNSQLENLKKSMEESEEGDKKTLVEMNQKISDLNSMI 545

Query: 551 SDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAE 610
           S++ K I     E+     ++  L  E  +LQ  L   D  +    D   K+I  +   +
Sbjct: 546 SENEKIIEEKQSEIDQKQSEIDSLSHENQDLQQKL---DEMKQNYEDEKSKLISEKESVD 602

Query: 611 TRLKAI-SLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLE 665
             L  + +  E +K    +++  L ++ +E+  +  ++S+  +D+  + I+  + E
Sbjct: 603 HELNELKNKSEQEKSQNEEKIEKLNKEIEEINKQNEELSKQNNDEFSNLIQEKNNE 658



 Score = 41.9 bits (94), Expect = 0.14
 Identities = 66/312 (21%), Positives = 135/312 (43%), Gaps = 27/312 (8%)

Query: 143 DVTHLSNTIKEKDNALSVLQVKMKIMETTILD----LQEKINEKDQ---IIEAKNKATTX 195
           ++  L +   EK  A++ LQ         +L     L  KI+E +     ++++NK  T 
Sbjct: 350 EIEKLKSENNEKSQAITDLQSSNNTNNENLLKQLDLLSSKISELENSSLALKSENKTLTE 409

Query: 196 XXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWK-------DEKQRLLKDIESKDV 248
                           E    + +K+Q+    ++A+ +       DE  +L   I+SKD 
Sbjct: 410 QIGSLDHENSKLKRDFEVLSNEKSKLQKENDKVKADIEQLSLSNSDEIGKLNDLIQSKDN 469

Query: 249 RISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCE--E 306
           +IS L++ N      + ++  E  + A+E+E               L K+S+E S E  +
Sbjct: 470 QISELQKENDENMTNKAKLEEEIKRSAEEIENKEKEIESLNSQLENL-KKSMEESEEGDK 528

Query: 307 KTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKEL-----ENKLATMGTESKAVSS 361
           KT +E    +   N + +++  +++E    +I Q   E+     EN+      +    + 
Sbjct: 529 KTLVEMNQKISDLN-SMISENEKIIEEKQSEIDQKQSEIDSLSHENQDLQQKLDEMKQNY 587

Query: 362 PSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDL 421
             +K   +  ++S  +  +++K+   Q  S+  N++  +K+NK EI ++    + L+K  
Sbjct: 588 EDEKSKLISEKESVDHELNELKNKSEQEKSQ--NEEKIEKLNK-EIEEINKQNEELSKQN 644

Query: 422 VDK-EYVISEKD 432
            D+   +I EK+
Sbjct: 645 NDEFSNLIQEKN 656



 Score = 40.3 bits (90), Expect = 0.43
 Identities = 45/225 (20%), Positives = 92/225 (40%), Gaps = 14/225 (6%)

Query: 143 DVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXX 202
           ++  L++ I+ KDN +S LQ +     T    L+E+I    + IE K K           
Sbjct: 456 EIGKLNDLIQSKDNQISELQKENDENMTNKAKLEEEIKRSAEEIENKEKEIESLNSQLEN 515

Query: 203 XXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEA 262
                    E  K+ + +M +    + +   + +    K IE K    S +++    +++
Sbjct: 516 LKKSMEESEEGDKKTLVEMNQKISDLNSMISENE----KIIEEKQ---SEIDQKQSEIDS 568

Query: 263 ARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEE-KTEIEEKGSLEIANM 321
               +S E+  L Q+L++                K+S++    E K + E++ S     +
Sbjct: 569 ----LSHENQDLQQKLDEMKQNYEDEKSKLIS-EKESVDHELNELKNKSEQEKSQNEEKI 623

Query: 322 TELTKKIELLEHLNCQI-RQTNKELENKLATMGTESKAVSSPSKK 365
            +L K+IE +   N ++ +Q N E  N +     E   ++  + +
Sbjct: 624 EKLNKEIEEINKQNEELSKQNNDEFSNLIQEKNNEINKLNEETSR 668


>UniRef50_A0DV70 Cluster: Chromosome undetermined scaffold_65, whole
            genome shotgun sequence; n=1; Paramecium tetraurelia|Rep:
            Chromosome undetermined scaffold_65, whole genome shotgun
            sequence - Paramecium tetraurelia
          Length = 1653

 Score =  123 bits (296), Expect = 5e-26
 Identities = 281/1462 (19%), Positives = 589/1462 (40%), Gaps = 149/1462 (10%)

Query: 143  DVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXX 202
            ++T L   +    +   V     +  E TI  L++KI E D  I+   +A          
Sbjct: 212  EITRLMQELARHQSEAQVRTSDKEFYERTIQTLKDKIKEMDNDIQILIEAHNQNQFKLES 271

Query: 203  XXXXXXXXXEDTKQQMTKMQENFIAMEA-EWKDEKQRLLKDIESKDVRISSLE----EAN 257
                     +    Q+ + + NF   +  +W+++ Q      E  + RI  +E    E  
Sbjct: 272  AMAESKGNMQYEIDQL-RQEVNFYQTQCKQWQEKCQVFELQKEESERRIIQMEIRVNETK 330

Query: 258  KLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLE 317
            K +E  + E     S     ++                 K S       K   ++   L 
Sbjct: 331  KQIELQQNERIQRDSWQVHTIQNELENWKQKYIQLEIKTKDSETHRLRIKQLEDQNNHLR 390

Query: 318  IANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRN 377
            I N   + +++++L      I++ N      +  +  +SK+     +  + +       N
Sbjct: 391  IEN-ERVKEELDILVTEFKSIQEQNNGYRLSITQLEKQSKSTVELDRYKTQVNQLNQQIN 449

Query: 378  TASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXX 437
                 K    QL  + + Q  +K+I      + +   ++  K++        + +     
Sbjct: 450  N---YKVEIKQLQEQMIVQQQEKRIEIQSYTQYQYEAENHQKEIEKLRREFRQIEQLYNE 506

Query: 438  XXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELND-EIKDV 496
                           QL+HQ+  +   LI V T  E    I    EQ K  +   E++ +
Sbjct: 507  MEVQVKLWKEKFYHEQLQHQEARQ--LLIDVKTQYESHTYILTQTEQDKHRIQQLELQLI 564

Query: 497  NVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNF-SKVSDSNK 555
             +++ +  L+  EE   +         +N IK   +   K++Q++  I+   SK  D  K
Sbjct: 565  ELQEEVRVLQIREETYKEQISTYSVTIEN-IKQNQDQSRKVRQLELDIETLKSKCRDLEK 623

Query: 556  EIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKA 615
            +++    E + L    +E E +K  +       D     + ++ K++IE  +  E +LK 
Sbjct: 624  QLLDKRNEFNLLK---SEWELDKQKITELKASNDVLLKRKPEIVKQIIETPSKQE-KLKI 679

Query: 616  ISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSV-HLEEQIDALSAS 674
              L +      +Q   +   K + + + + +  Q++S +   +IK + +LEE++      
Sbjct: 680  QELEQQVSLLKLQSQQVSASKQEVIRETIRETVQVRSQE---DIKLIANLEEELQLWKTK 736

Query: 675  KKEL-----ALVIENLK--LDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLT------ 721
              EL      +V+E ++     E     I++LE+  +    K Q  I+E +  T      
Sbjct: 737  YYELDRRKNQVVVETIREVQQSESDKLRIQELEHQVKQSSAKKQEIIREFITQTVEVPVE 796

Query: 722  -DKLEKMSAE-KISELLAKI---NHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKS 776
             DK+     E +++ L  +I   N  +Q  I  Q  ++   Q     I+ +ESE+ K K+
Sbjct: 797  ADKIRIQQLEIQVNNLRQEIYLLNQRKQEVITQQITVEVPSQADRQIIQQLESEIVKLKT 856

Query: 777  RICRLEES----IAVMEDRRYSLERKAD-----QLGSYLQEKQKAYSEYTIQEDELVNRL 827
            ++  + +S    I  +   R  +  ++D     QL + LQ  QK Y    +++ E++   
Sbjct: 857  QLEFVSKSKQEVIREIITERVEVPSESDKLKIQQLQTQLQRLQKDYQYLELKKQEIIKET 916

Query: 828  AVL-----MDHDRV--VEKQLLEIEHENKEL-QKKNQILLE---------------ENQN 864
              +      D  R+  +E QLL+I+ E + + QKK +I+ E               + Q 
Sbjct: 917  ITVEVPSQADKSRIQLLESQLLQIKKELQIVSQKKQEIITEYITERVEVPLESDRIKIQQ 976

Query: 865  LQISLSDMQQHYNALVEKANR----TDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQ 920
            L+  L  +QQ Y  L +K       T   E      Q +++ LES + ++  ++ ++I Q
Sbjct: 977  LESQLQKIQQEYYLLNQKKQEIIKETITVEVPQQSDQLRIQQLESLVVQLK-QNISIIQQ 1035

Query: 921  KKKEI------EDLEI----------EFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQL 964
            +K+E+      E +E+          +   +++   +D   LN+K ++ I+    +E   
Sbjct: 1036 QKQEVIRETITETVEVPSQKDKLRIQQLEQELQRLTQDYYQLNQKKQQIIKETVTVEVSS 1095

Query: 965  QEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEE 1024
            Q  K  I+ L   V++L     EL+    QKQ+      TE+    +      ++Q  ++
Sbjct: 1096 QADKFRIQQLESQVQQLKS---ELLIIQQQKQEVIREIITERVEVPVESDKIRIRQLQDQ 1152

Query: 1025 IIALNQKINNAQVSYMSMVSD---YESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEEL 1081
               L +  N   +    ++ +    E        +++ +E+ +Q++  + L+  Q+N E 
Sbjct: 1153 FSQLQRDYNQLNLKKQEVIRETVTVEVSSQADKYRIQQLEQSLQQMKMEYLNL-QNNYE- 1210

Query: 1082 QILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXX 1141
             I+ +++ + IKE+   ++       K     + S +  ++ +   +             
Sbjct: 1211 -IVSKKKQEVIKEVITERVEVSSPADKQRIAQLESQLSNLTMELQIISKKKQETIREVIT 1269

Query: 1142 LKVQEEEEFIQERSVLQEQSA-KLNTE---LQECYTKIIQLETLNTELTGHDVVNQEQIN 1197
             +V+  +E  + R +  EQ   KL  +   L +   ++I+ ET   E+      ++ +I 
Sbjct: 1270 ERVEVPKESDKRRIIELEQDLNKLQQDYIALNKTKQEVIK-ETYTIEVPSQ--ADKFKIQ 1326

Query: 1198 QLKSKLEQLNTENDNLLSTVAEL-RSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHE 1256
            QL+ +L Q+ +E   L S  AE+ R  +   V+     I +L +Q ++  + D+      
Sbjct: 1327 QLEMQLSQIRSEYQVLQSRKAEIVREVVEVPVESDRIRIRQL-EQQISSLQQDY------ 1379

Query: 1257 LRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADV 1316
                 S  + K E + ++V      E ++     ++  L+ +L    ++L  +Q++  +V
Sbjct: 1380 ----FSLNQKKQEVIKETVTIEVPSEADQY----RIRQLEQQLSTLRDNLTVIQKQKQEV 1431

Query: 1317 INQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQ------EQSILNI 1370
                +I++  ++  K                   +++   +  K+ Q      EQ I N+
Sbjct: 1432 ----QIIKETVQVSKQEDLFKIQNLERQLLQLQNEVQIYEKQLKEYQNSSFELEQEIKNL 1487

Query: 1371 NEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQR 1430
              +    +KS+            ++ + + K  ++  Q E ++ E  ++       L +R
Sbjct: 1488 RIQLRTTQKSNQEYQEQLTSIQIKIEEGQ-KSKQIQFQYERREQEFIEQIK----LLERR 1542

Query: 1431 NDEFENVRQQLVEYEKRIEDLTYEK-ESELAILRLKMHENANHYETMQKESEIERVKLIE 1489
            N+EF   R++  EYE+++     E+ ++E  I RLK+       +T +K+ E ER+  I+
Sbjct: 1543 NEEFRQERERYSEYERKLNYYKEEQLQNEKLIERLKL-----EIQTQKKQYE-ERIS-IQ 1595

Query: 1490 ELNVKITESVSLNKQVAELNKA 1511
            E   K   ++   +Q + +N++
Sbjct: 1596 ESQFKKEITIIQTQQQSNVNQS 1617



 Score =  110 bits (265), Expect = 3e-22
 Identities = 212/1080 (19%), Positives = 488/1080 (45%), Gaps = 115/1080 (10%)

Query: 529  VKSNHKLK--LKQMQKTIDNFSKVSDSN---KEIVRLTE-ELHHLSQKVAELEEEKGNLQ 582
            ++ N KLK  ++Q+ K      ++S  N   K+   + + EL    Q++A+L  +   L 
Sbjct: 66   LQDNRKLKEVIEQLDKDNQQLKQMSGENYNLKQKYMINQAELEAAQQELAKLRSQL--LM 123

Query: 583  LHLVDYDSGRMI---ESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDE 639
             +  D +S  ++   + D+   M + +  ++  +  ++ L +++   V+E   ++ KY++
Sbjct: 124  RNSSDAESSSLVARYKQDI-SSMTQQQIKSQQEITQLNALLTEQRKQVEEYLRIKSKYEQ 182

Query: 640  VEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASK-----KELALVIENLKL---DKEQ 691
                  DI   ++     E++   ++EQ ++ + S+     +ELA      ++   DKE 
Sbjct: 183  ------DIQTYKNRASTLELEIRSVKEQRNSTTQSEITRLMQELARHQSEAQVRTSDKEF 236

Query: 692  LYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKIN--HEEQSKIQT 749
               TI+ L++  +++ N +Q  I+ +     KLE   AE    +  +I+   +E +  QT
Sbjct: 237  YERTIQTLKDKIKEMDNDIQILIEAHNQNQFKLESAMAESKGNMQYEIDQLRQEVNFYQT 296

Query: 750  QF-GIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLER-KADQLGSYLQ 807
            Q      K Q  +L  E  E  + + + R+   ++ I + ++ R   +  +   + + L+
Sbjct: 297  QCKQWQEKCQVFELQKEESERRIIQMEIRVNETKKQIELQQNERIQRDSWQVHTIQNELE 356

Query: 808  EKQKAYSEYTIQ-EDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQ 866
              ++ Y +  I+ +D   +RL +     + +E Q   +  EN+ ++++  IL+ E +++Q
Sbjct: 357  NWKQKYIQLEIKTKDSETHRLRI-----KQLEDQNNHLRIENERVKEELDILVTEFKSIQ 411

Query: 867  ISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHE-----HQTLIVQK 921
                +    Y   + +  +   +  E  +Y+TQ+  L   +     E      Q ++ Q+
Sbjct: 412  ----EQNNGYRLSITQLEKQSKSTVELDRYKTQVNQLNQQINNYKVEIKQLQEQMIVQQQ 467

Query: 922  KKEIE-DLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEE 980
            +K IE     ++  + E+  ++ + L  ++ +  +   ++E Q++ +K    +  +  +E
Sbjct: 468  EKRIEIQSYTQYQYEAENHQKEIEKLRREFRQIEQLYNEMEVQVKLWKEKFYHEQLQHQE 527

Query: 981  LNKMNLELIDKHVQ-KQQTQSPDYTEQYINEINKLNALLKQKDEE--IIALNQKINNAQV 1037
              ++   LID   Q +  T     TEQ  + I +L   L +  EE  ++ + ++    Q+
Sbjct: 528  ARQL---LIDVKTQYESHTYILTQTEQDKHRIQQLELQLIELQEEVRVLQIREETYKEQI 584

Query: 1038 SYMSMV-------SDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDD 1090
            S  S+         D   K+ Q    +E ++ + + + KQLLD +    E  +L  E + 
Sbjct: 585  STYSVTIENIKQNQDQSRKVRQLELDIETLKSKCRDLEKQLLDKR---NEFNLLKSEWEL 641

Query: 1091 QIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEF 1150
              +++ E K + ++ + K +  I+   IE  S                   LK+QE E  
Sbjct: 642  DKQKITELKASNDV-LLKRKPEIVKQIIETPSKQEK---------------LKIQELE-- 683

Query: 1151 IQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHD---VVNQEQINQL-KSKLEQL 1206
             Q+ S+L+ QS +++   QE   + I+ ET+    +  D   + N E+  QL K+K  +L
Sbjct: 684  -QQVSLLKLQSQQVSASKQEVIRETIR-ETVQVR-SQEDIKLIANLEEELQLWKTKYYEL 740

Query: 1207 N-TENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQK-TEHELRVQLSAF 1264
            +  +N  ++ T+ E++ S S  +  R  E+    KQ  A+++   ++     + V + A 
Sbjct: 741  DRRKNQVVVETIREVQQSESDKL--RIQELEHQVKQSSAKKQEIIREFITQTVEVPVEAD 798

Query: 1265 ESKYEQLLDSVQSSTQE-----ETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQ 1319
            + + +QL   V +  QE     +  + V  +Q+T ++   Q   + ++ L+ +   +  Q
Sbjct: 799  KIRIQQLEIQVNNLRQEIYLLNQRKQEVITQQIT-VEVPSQADRQIIQQLESEIVKLKTQ 857

Query: 1320 IEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKK 1379
            +E + S+ + E +                    + + Q  +  ++   L + ++  ++ K
Sbjct: 858  LEFV-SKSKQEVIREIITERVEVPSESDKLKIQQLQTQLQRLQKDYQYLELKKQ--EIIK 914

Query: 1380 SSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRND-EFENVR 1438
             +            R+   E+++L++  +L++   +  +   EY   +T+R +   E+ R
Sbjct: 915  ETITVEVPSQADKSRIQLLESQLLQIKKELQIVSQKKQEIITEY---ITERVEVPLESDR 971

Query: 1439 QQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQ--KESEIERVKLIEELNVKIT 1496
             ++ + E +++ +    + E  +L  K  E      T++  ++S+  R++ +E L V++ 
Sbjct: 972  IKIQQLESQLQKI----QQEYYLLNQKKQEIIKETITVEVPQQSDQLRIQQLESLVVQLK 1027

Query: 1497 ESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNL-QNMVRASSSKIQ 1555
            +++S+ +Q  +  + + E + +T E+ +  +  ++ I  L  E+  L Q+  + +  K Q
Sbjct: 1028 QNISIIQQ--QKQEVIRETITETVEVPS--QKDKLRIQQLEQELQRLTQDYYQLNQKKQQ 1083



 Score = 70.9 bits (166), Expect = 3e-10
 Identities = 140/692 (20%), Positives = 282/692 (40%), Gaps = 65/692 (9%)

Query: 895  KYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEI--EFNTQIESAIRDKKVLN---EK 949
            KYQT    + S  KR+   +Q+   +K    ED +I    + + E  ++D + L    E+
Sbjct: 21   KYQTTSGVVSSAEKRVIEINQS--TRKSLMFEDKQITHPIHRRYEELLQDNRKLKEVIEQ 78

Query: 950  YEKNIEYVTQLEAQ----LQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTE 1005
             +K+ + + Q+  +     Q+Y  N   L    +EL K+  +L+ ++      +S     
Sbjct: 79   LDKDNQQLKQMSGENYNLKQKYMINQAELEAAQQELAKLRSQLLMRN--SSDAESSSLVA 136

Query: 1006 QYINEINKLNALLKQKDEEIIALNQKI--NNAQV-SYMSMVSDYESKLAQFTTKLENMEE 1062
            +Y  +I+ +     +  +EI  LN  +     QV  Y+ + S YE  +  +  +   +E 
Sbjct: 137  RYKQDISSMTQQQIKSQQEITQLNALLTEQRKQVEEYLRIKSKYEQDIQTYKNRASTLEL 196

Query: 1063 EMQRVSKQLLDSKQH--NEELQILVREQDD-QI----KELKETKLTFEMNIPKTEGMIIS 1115
            E++ V +Q   + Q      +Q L R Q + Q+    KE  E  +    +  K     I 
Sbjct: 197  EIRSVKEQRNSTTQSEITRLMQELARHQSEAQVRTSDKEFYERTIQTLKDKIKEMDNDIQ 256

Query: 1116 STIEPMSDDANNVDXXXXXXXXXXXXL--KVQEEEEFIQER-SVLQEQSAKLNTELQECY 1172
              IE  + +   ++               ++++E  F Q +    QE+      + +E  
Sbjct: 257  ILIEAHNQNQFKLESAMAESKGNMQYEIDQLRQEVNFYQTQCKQWQEKCQVFELQKEESE 316

Query: 1173 TKIIQLE-TLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQR 1231
             +IIQ+E  +N      ++   E+I +   ++  +  E +N      +L      +   R
Sbjct: 317  RRIIQMEIRVNETKKQIELQQNERIQRDSWQVHTIQNELENWKQKYIQLEIKTKDSETHR 376

Query: 1232 GFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTME- 1290
               I +L  Q+   R  + ++ + EL + ++ F+S  EQ      S TQ E     T+E 
Sbjct: 377  -LRIKQLEDQNNHLR-IENERVKEELDILVTEFKSIQEQNNGYRLSITQLEKQSKSTVEL 434

Query: 1291 -----QVTSLQNKLQDKEEHLRNL--------QEKYADVIN----QIEILRSEIEDEKVA 1333
                 QV  L  ++ + +  ++ L        QEK  ++ +    Q E    + E EK+ 
Sbjct: 435  DRYKTQVNQLNQQINNYKVEIKQLQEQMIVQQQEKRIEIQSYTQYQYEAENHQKEIEKLR 494

Query: 1334 FXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXX 1393
                              L  E   ++Q+Q Q    +  +     +S             
Sbjct: 495  REFRQIEQLYNEMEVQVKLWKEKFYHEQLQHQEARQLLIDVKTQYESHTYILTQTEQDKH 554

Query: 1394 RVNDAEAKVLELTHQ---LELKDSEIYQKTHEYTIT---LTQRNDEFENVRQQLVEYEKR 1447
            R+   E +++EL  +   L++++    ++   Y++T   + Q  D+   VRQ     E  
Sbjct: 555  RIQQLELQLIELQEEVRVLQIREETYKEQISTYSVTIENIKQNQDQSRKVRQ----LELD 610

Query: 1448 IEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAE 1507
            IE L    +S+   L  ++ +  N +  ++ E E+++ K+ E   +K +  V L K+  E
Sbjct: 611  IETL----KSKCRDLEKQLLDKRNEFNLLKSEWELDKQKITE---LKASNDVLL-KRKPE 662

Query: 1508 LNKALEEEVAKTNEMQTALENQEIEIVTLNDE 1539
            + K + E  +K  +++     Q++ ++ L  +
Sbjct: 663  IVKQIIETPSKQEKLKIQELEQQVSLLKLQSQ 694



 Score = 70.5 bits (165), Expect = 4e-10
 Identities = 147/786 (18%), Positives = 336/786 (42%), Gaps = 67/786 (8%)

Query: 826  RLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANR 885
            R   L+  +R +++ + +++ +N++L++ +       Q   I+ ++++     L +  ++
Sbjct: 61   RYEELLQDNRKLKEVIEQLDKDNQQLKQMSGENYNLKQKYMINQAELEAAQQELAKLRSQ 120

Query: 886  TDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKV 945
              +  S   +  + +   + ++  +T + Q    Q+  ++  L  E   Q+E  +R K  
Sbjct: 121  LLMRNSSDAESSSLVARYKQDISSMTQQ-QIKSQQEITQLNALLTEQRKQVEEYLRIKS- 178

Query: 946  LNEKYEKNIEYVTQLEAQLQ-EYKNNIENLNMNVE-ELNKMNLELIDKHVQKQQTQSPDY 1003
               KYE++I+      + L+ E ++  E  N   + E+ ++  EL  +H  + Q ++ D 
Sbjct: 179  ---KYEQDIQTYKNRASTLELEIRSVKEQRNSTTQSEITRLMQELA-RHQSEAQVRTSD- 233

Query: 1004 TEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSD------YE-SKLAQ---- 1052
             E Y   I  L   +K+ D +I  L +  N  Q    S +++      YE  +L Q    
Sbjct: 234  KEFYERTIQTLKDKIKEMDNDIQILIEAHNQNQFKLESAMAESKGNMQYEIDQLRQEVNF 293

Query: 1053 FTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKL--------TFEM 1104
            + T+ +  +E+ Q    Q  +S++   +++I V E   QI+  +  ++        T + 
Sbjct: 294  YQTQCKQWQEKCQVFELQKEESERRIIQMEIRVNETKKQIELQQNERIQRDSWQVHTIQN 353

Query: 1105 NIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXL---KVQEEEEF-IQERSVLQEQ 1160
             +   +   I   I+    + + +             +   +V+EE +  + E   +QEQ
Sbjct: 354  ELENWKQKYIQLEIKTKDSETHRLRIKQLEDQNNHLRIENERVKEELDILVTEFKSIQEQ 413

Query: 1161 SA--KLN-TELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTV 1217
            +   +L+ T+L++     ++L+   T++   + +NQ QIN  K +++QL    + ++   
Sbjct: 414  NNGYRLSITQLEKQSKSTVELDRYKTQV---NQLNQ-QINNYKVEIKQLQ---EQMIVQQ 466

Query: 1218 AELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTE---HELRVQLSAFESKY--EQLL 1272
             E R  I S   Q  +E AE  ++ + +   +F++ E   +E+ VQ+  ++ K+  EQL 
Sbjct: 467  QEKRIEIQSYT-QYQYE-AENHQKEIEKLRREFRQIEQLYNEMEVQVKLWKEKFYHEQLQ 524

Query: 1273 DS------VQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSE 1326
                    +   TQ E++  + + Q    ++++Q  E  L  LQE+   +  + E  + +
Sbjct: 525  HQEARQLLIDVKTQYESHTYI-LTQTEQDKHRIQQLELQLIELQEEVRVLQIREETYKEQ 583

Query: 1327 IEDEKVAFXXXXXXXXXXXXXXXX--DLRTENQSYKQMQEQSILNINEENAQLKKSSXXX 1384
            I    V                    D+ T     + +++Q +   NE N  L KS    
Sbjct: 584  ISTYSVTIENIKQNQDQSRKVRQLELDIETLKSKCRDLEKQLLDKRNEFN--LLKSEWEL 641

Query: 1385 XXXXXXXXXRVNDAEAK----VLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQ 1440
                       ND   K    +++   +   K  ++  +  E  ++L +   +  +  +Q
Sbjct: 642  DKQKITELKASNDVLLKRKPEIVKQIIETPSKQEKLKIQELEQQVSLLKLQSQQVSASKQ 701

Query: 1441 LVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVS 1500
             V  E   E +    + ++ ++   + E    ++T   E +  + +++ E   ++ +S S
Sbjct: 702  EVIRETIRETVQVRSQEDIKLIA-NLEEELQLWKTKYYELDRRKNQVVVETIREVQQSES 760

Query: 1501 LNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSF 1560
               ++ EL   +++  AK  E+      Q +E+    D+I   Q  ++ ++  +++ +  
Sbjct: 761  DKLRIQELEHQVKQSSAKKQEIIREFITQTVEVPVEADKIRIQQLEIQVNN--LRQEIYL 818

Query: 1561 ASDTKQ 1566
             +  KQ
Sbjct: 819  LNQRKQ 824



 Score = 68.9 bits (161), Expect = 1e-09
 Identities = 146/845 (17%), Positives = 345/845 (40%), Gaps = 59/845 (6%)

Query: 730  EKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVME 789
            +++ E L K N + +      + +  K       +E  + EL+K +S++     S A   
Sbjct: 73   KEVIEQLDKDNQQLKQMSGENYNLKQKYMINQAELEAAQQELAKLRSQLLMRNSSDA--- 129

Query: 790  DRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIE-HEN 848
            +    + R    + S  Q++ K+  E T     L  +   + ++ R+  K   +I+ ++N
Sbjct: 130  ESSSLVARYKQDISSMTQQQIKSQQEITQLNALLTEQRKQVEEYLRIKSKYEQDIQTYKN 189

Query: 849  KELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLK 908
            +    + +I   + Q    + S++ +    L    +   +  S+   Y+  ++ L+  +K
Sbjct: 190  RASTLELEIRSVKEQRNSTTQSEITRLMQELARHQSEAQVRTSDKEFYERTIQTLKDKIK 249

Query: 909  RITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYK 968
             + ++ Q LI    +    LE   +   ES    +  +++  ++   Y TQ + Q QE K
Sbjct: 250  EMDNDIQILIEAHNQNQFKLE---SAMAESKGNMQYEIDQLRQEVNFYQTQCK-QWQE-K 304

Query: 969  NNIENLNMNVEELNKMNLELIDKHVQKQ-QTQSPDYTEQYINEINKLNALLKQKDEEIIA 1027
              +  L     E   + +E+     +KQ + Q  +  ++   +++ +   L+   ++ I 
Sbjct: 305  CQVFELQKEESERRIIQMEIRVNETKKQIELQQNERIQRDSWQVHTIQNELENWKQKYIQ 364

Query: 1028 LNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVRE 1087
            L  K  +++ ++   +   E +      + E ++EE+  +  +    ++ N   ++ + +
Sbjct: 365  LEIKTKDSE-THRLRIKQLEDQNNHLRIENERVKEELDILVTEFKSIQEQNNGYRLSITQ 423

Query: 1088 QDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEE 1147
             +      K++K T E++  KT+       +  ++   NN              + VQ++
Sbjct: 424  LE------KQSKSTVELDRYKTQ-------VNQLNQQINNYKVEIKQLQEQ---MIVQQQ 467

Query: 1148 EEFIQERSVLQEQSAKLN--TELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKL-- 1203
            E+ I+ +S  Q Q    N   E+++   +  Q+E L  E+       + Q+   K K   
Sbjct: 468  EKRIEIQSYTQYQYEAENHQKEIEKLRREFRQIEQLYNEM-------EVQVKLWKEKFYH 520

Query: 1204 EQL-NTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLS 1262
            EQL + E   LL  V     S +  + Q      E  K  + Q E    + + E+RV L 
Sbjct: 521  EQLQHQEARQLLIDVKTQYESHTYILTQ-----TEQDKHRIQQLELQLIELQEEVRV-LQ 574

Query: 1263 AFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEI 1322
              E  Y++ + +   + +          +V  L+  ++  +   R+L+++  D  N+  +
Sbjct: 575  IREETYKEQISTYSVTIENIKQNQDQSRKVRQLELDIETLKSKCRDLEKQLLDKRNEFNL 634

Query: 1323 LRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSX 1382
            L+SE E +K                    ++   ++  + ++  I  + ++ + LK  S 
Sbjct: 635  LKSEWELDKQKITELKASNDVLLKRKPEIVKQIIETPSKQEKLKIQELEQQVSLLKLQSQ 694

Query: 1383 XXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLV 1442
                        + +   + +++  Q ++K   +     E       +  E +  + Q+V
Sbjct: 695  QVSASKQEV---IRETIRETVQVRSQEDIK---LIANLEEELQLWKTKYYELDRRKNQVV 748

Query: 1443 EYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKI-TESVSL 1501
                 +E +   ++SE   LR++  E+     + +K+ EI R  + + + V +  + + +
Sbjct: 749  -----VETIREVQQSESDKLRIQELEHQVKQSSAKKQ-EIIREFITQTVEVPVEADKIRI 802

Query: 1502 NKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFA 1561
             +   ++N  L +E+   N+ +  +  Q+I +   +     +   + +   K++  + F 
Sbjct: 803  QQLEIQVNN-LRQEIYLLNQRKQEVITQQITVEVPSQADRQIIQQLESEIVKLKTQLEFV 861

Query: 1562 SDTKQ 1566
            S +KQ
Sbjct: 862  SKSKQ 866


>UniRef50_A0CTT0 Cluster: Chromosome undetermined scaffold_27, whole
            genome shotgun sequence; n=1; Paramecium tetraurelia|Rep:
            Chromosome undetermined scaffold_27, whole genome shotgun
            sequence - Paramecium tetraurelia
          Length = 1028

 Score =  123 bits (296), Expect = 5e-26
 Identities = 194/941 (20%), Positives = 411/941 (43%), Gaps = 87/941 (9%)

Query: 476  NEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVK---SN 532
            N++ K   +LKQ     +   N   L ++ + A +QI +   +ID  NK +  ++   S+
Sbjct: 73   NDLVKYINELKQSSGGTLDQFN--QLKKQYEEALQQINKQKIDIDELNKRIRSLEQELSD 130

Query: 533  HKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQK----VAELEEEKGNLQLHLVDY 588
             K K  Q+ +T+    K++D+ K+        ++L  K    + + + +   L    +D+
Sbjct: 131  AKSKYGQVDQTLPQ--KLADAEKKWKEFESLYNNLKLKYDTDIRDWQLKYDELNRKALDW 188

Query: 589  DSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADIS 648
            +    I   + ++M +M++  E  L++      Q  D ++E  + Q  +D  +  L    
Sbjct: 189  ERRYGI---LEQQMKQMQDDHELELRSSGDSAKQYEDQLREWELKQNDWDNKQKAL---- 241

Query: 649  QLQSDQVCSEIKSVHLE-EQIDA-LSASKKELALVIENLKLDKEQLYGTIKDLENDKEDI 706
            + + D++   +K+   E E++ A L A+++EL      L+ + +Q  G+ K  E + +  
Sbjct: 242  RAEQDRLNQLLKNKDDEYERLKAQLLAAQRELDDYKNKLR-ESDQASGS-KFTEYESKIA 299

Query: 707  MNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIEN 766
              +LQN  Q N DL ++L+K   + + + L ++  + QS+       D+K+ E      N
Sbjct: 300  ELRLQNQ-QLNQDL-ERLKKRYQD-LEDQLNRLQSQNQSQ-------DSKVSELQSKCGN 349

Query: 767  IESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNR 826
            +E+E+ K  + +   E+ I  ++ ++  LE++  +L            E  +   ++ ++
Sbjct: 350  LENEVEKLNNDLRDKEQEITKLQGKQMQLEQRNKELTD----------ENNLLRKKVADQ 399

Query: 827  LAVLMDHDRVVEKQLLEIEHENKEL---QKKNQILLEENQNLQISLSDMQQHYNALVEKA 883
             A +   +  + +++ EIE+ N  L    ++N+ LL +  +LQ  L D + +Y  L E  
Sbjct: 400  KAEIERLELELRQKISEIEYYNLNLVNQDERNKQLLNQVDDLQFQLQDFKTNYQQLEEDF 459

Query: 884  NRTDLAESESTKYQTQLRDLE-SNLKRITHEHQTLIVQKKKEIEDLEIE---FNTQIESA 939
            NR    ++E  + +  L   E   +K I       + + +++I  LEIE   F  QIE  
Sbjct: 460  NRLQ-KKNEDLENKCALFSAEIDRMKNIIKLKNQDLEKLRRQIGSLEIEKKFFEQQIEDL 518

Query: 940  IRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMN--LELIDKHVQKQQ 997
            +   K + ++  K  E + +   QLQ+  N I +LN  + E+  +    +  DK + +  
Sbjct: 519  LNKMKQMQDEIVKLNELLKERLKQLQQQNNTIISLNHQLGEMKALQTYCDQQDKRINETT 578

Query: 998  TQSPD------YTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYE---- 1047
             +  +      + +  +  I+ L A +++++++   LN +I   Q   ++ + + +    
Sbjct: 579  NKLNEALLQLQFKDIELMNISALQASIQEREKQAELLNNEIVRLQNDIINKLKESDDQKE 638

Query: 1048 --SKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETK----LT 1101
               KL     +L+  E+ +  + ++L ++ +    L+    + ++Q+   +++     +T
Sbjct: 639  QIKKLNDEIARLKTQEQNLHDIERKLQNAVEEINRLESQKSDLENQVSVNRQSSPKHTIT 698

Query: 1102 FEMNIPKTEGMIISSTIEPMSDDAN----NVDXXXXXXXXXXXXLKVQEEEEFIQERSVL 1157
             E+ I KT   + ++ I+ +  D       +D            LK    E++I   +VL
Sbjct: 699  KEIRIEKTSVQVDTTEIDKLKQDLRQKQFELDQLNNQLLISQNALK--SAEDYI---AVL 753

Query: 1158 QEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTV 1217
              +   LN E ++      QLE +  + T      Q+++  L+ +L Q   +N+ +L   
Sbjct: 754  LNRINILNKENEDMLQGKQQLE-IQVQDTR---TLQDKLQNLEKQLTQFRNDNERILREF 809

Query: 1218 AELRSSISSAVDQRGFEIAELWKQHLAQRE--ADFQKTEHELRVQLSAFESKYEQLLDSV 1275
             E     S   D    +I++L  Q    RE  A  ++ E++L    +  E    QL +  
Sbjct: 810  KEK----SKLYDDARQKISKLEAQATEARELQAKLREIENKLVFAQTNQERLTAQLAEKT 865

Query: 1276 QSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFX 1335
            + +   + N  +   ++T L  +LQ   E  R L+E+   ++   + L +     +V   
Sbjct: 866  EENNNLKQNLQIANNEITKLSEQLQQLSEQERLLKEQVNHLLQDKDALDNLKRQHEVLIA 925

Query: 1336 XXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQ 1376
                               +NQ  +  QE   L I +E  +
Sbjct: 926  DISKANQNIDQLSIERDSLDNQLKQNQQELEKLRILQEKVR 966



 Score = 88.2 bits (209), Expect = 2e-15
 Identities = 138/738 (18%), Positives = 304/738 (41%), Gaps = 57/738 (7%)

Query: 844  IEHENKELQKKNQI----LLEENQNLQISLSDMQQHYNALVEKANRT-DLAESESTKYQT 898
            + +E K L K  ++    L  EN  L    +D+ ++ N L + +  T D       +Y+ 
Sbjct: 43   VSNERKWLGKNPEVVCFLLALENDRLVRENNDLVKYINELKQSSGGTLDQFNQLKKQYEE 102

Query: 899  QLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVT 958
             L+ +    K    E    I   ++E+ D + ++  Q++  +  K    EK  K  E + 
Sbjct: 103  ALQQINKQ-KIDIDELNKRIRSLEQELSDAKSKYG-QVDQTLPQKLADAEKKWKEFESLY 160

Query: 959  QLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALL 1018
                +L+ Y  +I +  +  +ELN+  L+   ++   +Q Q     + +  E+       
Sbjct: 161  N-NLKLK-YDTDIRDWQLKYDELNRKALDWERRYGILEQ-QMKQMQDDHELELRSSGDSA 217

Query: 1019 KQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHN 1078
            KQ ++++     K N+      ++ ++ + +L Q    L+N ++E +R+  QLL +++  
Sbjct: 218  KQYEDQLREWELKQNDWDNKQKALRAE-QDRLNQL---LKNKDDEYERLKAQLLAAQREL 273

Query: 1079 EELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXX 1138
            ++ +  +RE D Q    K T+   ++   + +   ++  +E +     +++         
Sbjct: 274  DDYKNKLRESD-QASGSKFTEYESKIAELRLQNQQLNQDLERLKKRYQDLEDQLNRLQSQ 332

Query: 1139 XXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQ 1198
                +  +  E   +   L+ +  KLN +L++   +I +L+    +L   +    ++ N 
Sbjct: 333  NQS-QDSKVSELQSKCGNLENEVEKLNNDLRDKEQEITKLQGKQMQLEQRNKELTDENNL 391

Query: 1199 LKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELR 1258
            L+ K+     E + L     ELR  IS        E   L   +  +R         +L+
Sbjct: 392  LRKKVADQKAEIERL---ELELRQKISE------IEYYNLNLVNQDERNKQLLNQVDDLQ 442

Query: 1259 VQLSAFESKYEQL---LDSVQSSTQEETNKIVTME-QVTSLQNKLQDKEEHLRNLQEKYA 1314
             QL  F++ Y+QL    + +Q   ++  NK      ++  ++N ++ K + L  L+ +  
Sbjct: 443  FQLQDFKTNYQQLEEDFNRLQKKNEDLENKCALFSAEIDRMKNIIKLKNQDLEKLRRQIG 502

Query: 1315 DVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEEN 1374
             +  + +    +IED                     +L  E     Q Q  +I+++N + 
Sbjct: 503  SLEIEKKFFEQQIED-----LLNKMKQMQDEIVKLNELLKERLKQLQQQNNTIISLNHQL 557

Query: 1375 AQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEF 1434
             ++K               R+N+   K+ E   QL+ KD E+         ++ +R  + 
Sbjct: 558  GEMK----ALQTYCDQQDKRINETTNKLNEALLQLQFKDIEL-MNISALQASIQEREKQA 612

Query: 1435 ENVRQQLVEYEKRIEDLTYEKESELA--------ILRLKMHENANHYETMQKESEIERVK 1486
            E +  ++V  +  I +   E + +          I RLK  E   H    + ++ +E + 
Sbjct: 613  ELLNNEIVRLQNDIINKLKESDDQKEQIKKLNDEIARLKTQEQNLHDIERKLQNAVEEIN 672

Query: 1487 LIEELNVKITESVSLNKQVAELNKALEE-EVAKT---------NEMQTALENQEIEIVTL 1536
             +E     +   VS+N+Q +  +   +E  + KT         ++++  L  ++ E+  L
Sbjct: 673  RLESQKSDLENQVSVNRQSSPKHTITKEIRIEKTSVQVDTTEIDKLKQDLRQKQFELDQL 732

Query: 1537 NDEITNLQNMVRASSSKI 1554
            N+++   QN ++++   I
Sbjct: 733  NNQLLISQNALKSAEDYI 750



 Score = 85.4 bits (202), Expect = 1e-14
 Identities = 166/813 (20%), Positives = 343/813 (42%), Gaps = 71/813 (8%)

Query: 147  LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXX 206
            L+  +K KD+    L+ ++   +  + D + K+ E DQ       A+             
Sbjct: 248  LNQLLKNKDDEYERLKAQLLAAQRELDDYKNKLRESDQ-------ASGSKFTEYESKIAE 300

Query: 207  XXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFE 266
                 +   Q + ++++ +  +E    D+  RL    +S+D ++S L+     LE    +
Sbjct: 301  LRLQNQQLNQDLERLKKRYQDLE----DQLNRLQSQNQSQDSKVSELQSKCGNLENEVEK 356

Query: 267  ISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTK 326
            ++ +     QE+ +              L  ++   +   K   ++K  +E   + EL +
Sbjct: 357  LNNDLRDKEQEITKLQGKQMQLEQRNKELTDEN---NLLRKKVADQKAEIERLEL-ELRQ 412

Query: 327  KIELLEHLNCQI---RQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMK 383
            KI  +E+ N  +    + NK+L N++  +  + +   +  ++     +R   +N   + K
Sbjct: 413  KISEIEYYNLNLVNQDERNKQLLNQVDDLQFQLQDFKTNYQQLEEDFNRLQKKNEDLENK 472

Query: 384  SPWSQLSSETL-------NQDTDK---KINKNEIAK--LEMVIQSL-NKDLVDKEYVISE 430
                    + +       NQD +K   +I   EI K   E  I+ L NK    ++ ++  
Sbjct: 473  CALFSAEIDRMKNIIKLKNQDLEKLRRQIGSLEIEKKFFEQQIEDLLNKMKQMQDEIVKL 532

Query: 431  KDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIA-KVQEQLKQEL 489
             +             +T+I+   L HQ         +     + +NE   K+ E L Q  
Sbjct: 533  NELLKERLKQLQQQNNTIIS---LNHQLGEMKALQTYCDQQDKRINETTNKLNEALLQLQ 589

Query: 490  NDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSK 549
              +I+ +N+  L   ++  E+Q   LN+EI     ++I        KLK+     +   K
Sbjct: 590  FKDIELMNISALQASIQEREKQAELLNNEIVRLQNDIIN-------KLKESDDQKEQIKK 642

Query: 550  VSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMI-ESDVYKKMIEMENL 608
            ++D    +    + LH + +K+    EE   L+    D ++   +      K  I  E  
Sbjct: 643  LNDEIARLKTQEQNLHDIERKLQNAVEEINRLESQKSDLENQVSVNRQSSPKHTITKEIR 702

Query: 609  AETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQ--LQS--DQVCSEIKSVH- 663
             E     +   E  K  L Q+L   Q + D++ ++L  ISQ  L+S  D +   +  ++ 
Sbjct: 703  IEKTSVQVDTTEIDK--LKQDLRQKQFELDQLNNQLL-ISQNALKSAEDYIAVLLNRINI 759

Query: 664  LEEQIDALSASKKELALVIENLKLDKEQLYGTIKDL---ENDKEDIMNKLQNYIQENMDL 720
            L ++ + +   K++L + +++ +  +++L    K L    ND E I+ + +   +   D 
Sbjct: 760  LNKENEDMLQGKQQLEIQVQDTRTLQDKLQNLEKQLTQFRNDNERILREFKEKSKLYDDA 819

Query: 721  TDKLEKMSAE--KISELLAKINHEEQSKI--QT-QFGIDAKIQERDLYIENIESELSKYK 775
              K+ K+ A+  +  EL AK+   E   +  QT Q  + A++ E+     N++  L    
Sbjct: 820  RQKISKLEAQATEARELQAKLREIENKLVFAQTNQERLTAQLAEKTEENNNLKQNLQIAN 879

Query: 776  SRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDR 835
            + I +L E +  + ++   L+   +Q+   LQ+K  A      Q + L+   A +   ++
Sbjct: 880  NEITKLSEQLQQLSEQERLLK---EQVNHLLQDKD-ALDNLKRQHEVLI---ADISKANQ 932

Query: 836  VVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTK 895
             +++  +E +  + +L K+NQ  LE+ + LQ  +  +    N L +K  R   AE+E   
Sbjct: 933  NIDQLSIERDSLDNQL-KQNQQELEKLRILQEKVRFLGGECNKLNDKLGR---AENELDN 988

Query: 896  YQTQLRDLESNLKRITHEHQTLIVQKKKEIEDL 928
            ++ + ++  S+L +   +    I +  KE+E+L
Sbjct: 989  FRKRGQE-NSDLNKQIIDKNGQIERLNKELENL 1020



 Score = 83.0 bits (196), Expect = 6e-14
 Identities = 131/686 (19%), Positives = 293/686 (42%), Gaps = 71/686 (10%)

Query: 944  KVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDY 1003
            K +NE  + +   + Q     ++Y+  ++ +N       K++++ ++K ++  + +  D 
Sbjct: 77   KYINELKQSSGGTLDQFNQLKKQYEEALQQINKQ-----KIDIDELNKRIRSLEQELSDA 131

Query: 1004 TEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEE 1063
              +Y      L   L   +++        NN ++ Y + + D++ K  +   K  + E  
Sbjct: 132  KSKYGQVDQTLPQKLADAEKKWKEFESLYNNLKLKYDTDIRDWQLKYDELNRKALDWERR 191

Query: 1064 MQRVSKQLLDSKQHNEELQIL-----VREQDDQIKE--LKETKLTFEMNIPKTEGMIISS 1116
               + +Q +   Q + EL++       ++ +DQ++E  LK+     +    + E   ++ 
Sbjct: 192  YG-ILEQQMKQMQDDHELELRSSGDSAKQYEDQLREWELKQNDWDNKQKALRAEQDRLNQ 250

Query: 1117 TIEPMSDDANNVDXXXXXXXXXXXXLK--VQEEEE-----FIQERSVLQE---QSAKLNT 1166
             ++   D+   +              K  ++E ++     F +  S + E   Q+ +LN 
Sbjct: 251  LLKNKDDEYERLKAQLLAAQRELDDYKNKLRESDQASGSKFTEYESKIAELRLQNQQLNQ 310

Query: 1167 ELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISS 1226
            +L+    +   LE     L   +     ++++L+SK   L  E + L + + +    I+ 
Sbjct: 311  DLERLKKRYQDLEDQLNRLQSQNQSQDSKVSELQSKCGNLENEVEKLNNDLRDKEQEITK 370

Query: 1227 A------VDQRGFEIAE---LWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQS 1277
                   ++QR  E+ +   L ++ +A ++A+ ++ E ELR ++S  E     L++    
Sbjct: 371  LQGKQMQLEQRNKELTDENNLLRKKVADQKAEIERLELELRQKISEIEYYNLNLVN---- 426

Query: 1278 STQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXX 1337
              Q+E NK + + QV  LQ +LQD + + + L+E +    N+++    ++E++   F   
Sbjct: 427  --QDERNKQL-LNQVDDLQFQLQDFKTNYQQLEEDF----NRLQKKNEDLENKCALFSAE 479

Query: 1338 XXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVND 1397
                          ++ +NQ  ++++ Q I ++  E    KK              ++ D
Sbjct: 480  IDRMKNI-------IKLKNQDLEKLRRQ-IGSLEIE----KKFFEQQIEDLLNKMKQMQD 527

Query: 1398 AEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKES 1457
               K+ EL  +  LK     Q+ +   I+L  +  E + ++    + +KRI + T +   
Sbjct: 528  EIVKLNELLKE-RLKQ---LQQQNNTIISLNHQLGEMKALQTYCDQQDKRINETTNKLNE 583

Query: 1458 ELAILRLKMHENAN------HYETMQKESEI---ERVKLIEELNVKITESVSLNKQVAEL 1508
             L  L+ K  E  N        +  +K++E+   E V+L  ++  K+ ES    +Q+ +L
Sbjct: 584  ALLQLQFKDIELMNISALQASIQEREKQAELLNNEIVRLQNDIINKLKESDDQKEQIKKL 643

Query: 1509 NKA---LEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTK 1565
            N     L+ +    ++++  L+N   EI  L  + ++L+N V  +     KH        
Sbjct: 644  NDEIARLKTQEQNLHDIERKLQNAVEEINRLESQKSDLENQVSVNRQSSPKHTITKEIRI 703

Query: 1566 QGRDEQLDNTMNKELLDAVPRAELDL 1591
            +    Q+D T   +L   + + + +L
Sbjct: 704  EKTSVQVDTTEIDKLKQDLRQKQFEL 729



 Score = 50.4 bits (115), Expect = 4e-04
 Identities = 64/362 (17%), Positives = 146/362 (40%), Gaps = 22/362 (6%)

Query: 1238 LWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQN 1297
            L    L +   D  K  +EL+        ++ QL    + + Q+   + + +++   L  
Sbjct: 63   LENDRLVRENNDLVKYINELKQSSGGTLDQFNQLKKQYEEALQQINKQKIDIDE---LNK 119

Query: 1298 KLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXD--LRTE 1355
            +++  E+ L + + KY  V   +    ++ E +   F                D  L+ +
Sbjct: 120  RIRSLEQELSDAKSKYGQVDQTLPQKLADAEKKWKEFESLYNNLKLKYDTDIRDWQLKYD 179

Query: 1356 NQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELT-HQLELKDS 1414
              + K +  +    I E+  +  +              +  + + +  EL  +  + K  
Sbjct: 180  ELNRKALDWERRYGILEQQMKQMQDDHELELRSSGDSAKQYEDQLREWELKQNDWDNKQK 239

Query: 1415 EIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYE-KESELAILRLKMHENANHY 1473
             +  +       L  ++DE+E ++ QL+  ++ ++D   + +ES+ A            Y
Sbjct: 240  ALRAEQDRLNQLLKNKDDEYERLKAQLLAAQRELDDYKNKLRESDQA-----SGSKFTEY 294

Query: 1474 ETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEI 1533
            E+   E  ++  +L ++L         L  Q+  L    + + +K +E+Q+   N E E+
Sbjct: 295  ESKIAELRLQNQQLNQDLERLKKRYQDLEDQLNRLQSQNQSQDSKVSELQSKCGNLENEV 354

Query: 1534 VTLNDEITNLQNMVRASSSKIQ-KHVSFASDTKQGRDEQLDNTMNKELLD---AVPRAEL 1589
              LN+++ + +  +    +K+Q K +      K+  DE  +N + K++ D    + R EL
Sbjct: 355  EKLNNDLRDKEQEI----TKLQGKQMQLEQRNKELTDE--NNLLRKKVADQKAEIERLEL 408

Query: 1590 DL 1591
            +L
Sbjct: 409  EL 410



 Score = 40.7 bits (91), Expect = 0.32
 Identities = 79/440 (17%), Positives = 180/440 (40%), Gaps = 24/440 (5%)

Query: 140  QLGDVTHLSNTIKEKDNALSVLQVKMKIMETTILD-LQEKINEKDQIIEAKNKATTXXXX 198
            +L +++ L  +I+E++    +L  ++  ++  I++ L+E  ++K+QI +  ++       
Sbjct: 594  ELMNISALQASIQEREKQAELLNNEIVRLQNDIINKLKESDDQKEQIKKLNDEIARLKTQ 653

Query: 199  XXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLE---- 254
                         ++  +++ +++     +E +    +Q   K   +K++RI        
Sbjct: 654  EQNLHDIERKL--QNAVEEINRLESQKSDLENQVSVNRQSSPKHTITKEIRIEKTSVQVD 711

Query: 255  --EANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEE 312
              E +KL +  R +   E  +L  +L                L  +    + E +  ++ 
Sbjct: 712  TTEIDKLKQDLR-QKQFELDQLNNQLLISQNALKSAEDYIAVLLNRINILNKENEDMLQG 770

Query: 313  KGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISR 372
            K  LEI      T + + L++L  Q+ Q   + E  L     +SK      +K S L ++
Sbjct: 771  KQQLEIQVQDTRTLQ-DKLQNLEKQLTQFRNDNERILREFKEKSKLYDDARQKISKLEAQ 829

Query: 373  KS-GRNTASKM-----KSPWSQLSSETLNQDTDKKINKNEIAK--LEMVIQSLNKDLVDK 424
             +  R   +K+     K  ++Q + E L     +K  +N   K  L++    + K L ++
Sbjct: 830  ATEARELQAKLREIENKLVFAQTNQERLTAQLAEKTEENNNLKQNLQIANNEITK-LSEQ 888

Query: 425  EYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQ 484
               +SE++                +  L+ +H+  +   S  +   +   + E   +  Q
Sbjct: 889  LQQLSEQERLLKEQVNHLLQDKDALDNLKRQHEVLIADISKANQNIDQLSI-ERDSLDNQ 947

Query: 485  LKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTI 544
            LKQ    E++ + +  L EK++    +  +LND++  A   +   +   +      ++ I
Sbjct: 948  LKQN-QQELEKLRI--LQEKVRFLGGECNKLNDKLGRAENELDNFRKRGQENSDLNKQII 1004

Query: 545  DNFSKVSDSNKEIVRLTEEL 564
            D   ++   NKE+  L ++L
Sbjct: 1005 DKNGQIERLNKELENLRKQL 1024


>UniRef50_P08799 Cluster: Myosin-2 heavy chain, non muscle; n=5;
            Dictyostelium discoideum|Rep: Myosin-2 heavy chain, non
            muscle - Dictyostelium discoideum (Slime mold)
          Length = 2116

 Score =  123 bits (296), Expect = 5e-26
 Identities = 231/1245 (18%), Positives = 508/1245 (40%), Gaps = 79/1245 (6%)

Query: 297  KQSIEPSCEEKTEIE-EKGSLEIA--NM-TELTKKIELLEHLNCQIRQTNKELENKLATM 352
            K++++   + K  +E +K  LEI   +M +EL +K   LE+L  Q R   +++ +    +
Sbjct: 876  KETLKAMYDSKDALEAQKRELEIRVEDMESELDEKKLALENLQNQKRSVEEKVRDLEEEL 935

Query: 353  GTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEM 412
              E K  ++  K       +K       +MK      S      +  K   + E+ +L  
Sbjct: 936  QEEQKLRNTLEKL------KKKYEEELEEMKRVNDGQSDTISRLEKIKDELQKEVEELTE 989

Query: 413  VIQSLNKD--LVDKEYVI--SEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHV 468
                 +KD  +++K  V   SE D            K  L+ Q +   ++  +    +  
Sbjct: 990  SFSEESKDKGVLEKTRVRLQSELDDLTVRLDSETKDKSELLRQKKKLEEELKQVQEALAA 1049

Query: 469  GTNTEDVNEIAKVQEQLKQ-ELNDEIK-DVNVKDLIEKLKSA-EEQITQLNDEIDAANKN 525
             T  +   E A  + Q +  ELN++   +V  +  +EK K   E Q+  +N+E+D   KN
Sbjct: 1050 ETAAKLAQEAANKKLQGEYTELNEKFNSEVTARSNVEKSKKTLESQLVAVNNELDEEKKN 1109

Query: 526  MIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEI----VRLTEELHHLSQKVAELEEEKGNL 581
               ++   K     +++  D         K +    V+   ++  L  +++EL+     L
Sbjct: 1110 RDALEKKKKALDAMLEEMKDQLESTGGEKKSLYDLKVKQESDMEALRNQISELQSTIAKL 1169

Query: 582  QL--HLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDE 639
            +     ++ +  R+ + ++  + +   N+ + + K    LE +   L +E    +Q  D+
Sbjct: 1170 EKIKSTLEGEVARL-QGELEAEQLAKSNVEKQKKKVELDLEDKSAQLAEET-AAKQALDK 1227

Query: 640  VEDKLA-DISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKD 698
            ++ KL  ++S++Q+    +  K+V+ +     L  S   L L +E  +  K+ L      
Sbjct: 1228 LKKKLEQELSEVQTQLSEANNKNVNSDSTNKHLETSFNNLKLELEAEQKAKQALEKKRLG 1287

Query: 699  LENDKEDIMNKLQNYIQENMDLTDKLEKMSAEK-ISELLAKINHEEQSKIQTQFGIDAKI 757
            LE++ + +  +L+   ++    +++  K+  EK +SEL  +I  E  SK       + K 
Sbjct: 1288 LESELKHVNEQLEE--EKKQKESNEKRKVDLEKEVSELKDQIEEEVASKKAVTEAKNKKE 1345

Query: 758  QERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYT 817
             E D         +S     + +L+   A  E+ R + E    QL    + K+KA  +  
Sbjct: 1346 SELDEIKRQYADVVSSRDKSVEQLKTLQAKNEELRNTAEEAEGQLDRAERSKKKAEFDLE 1405

Query: 818  IQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYN 877
                 L    A  +  ++ ++K   +      EL     +  E+   ++    ++ +  +
Sbjct: 1406 EAVKNLEEETAKKVKAEKAMKKAETDYRSTKSELDDAKNVSSEQYVQIKRLNEELSELRS 1465

Query: 878  ALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIE 937
             L E   R + A       ++ L  L+  +    +       + +++ ++LE+    ++E
Sbjct: 1466 VLEEADERCNSAIKAKKTAESALESLKDEIDAANNAK----AKAERKSKELEVRV-AELE 1520

Query: 938  SAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQ 997
             ++ DK         N+E++ + +A++ + +  ++      E  +++  +   K+ +KQ 
Sbjct: 1521 ESLEDKSGT-----VNVEFIRKKDAEIDDLRARLDR-----ETESRIKSDEDKKNTRKQF 1570

Query: 998  TQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKL 1057
                   E+   E+  ++ L K+ + +II L+ +++    S +  +   + KL Q   + 
Sbjct: 1571 ADLEAKVEEAQREVVTIDRLKKKLESDIIDLSTQLDTETKSRIK-IEKSKKKLEQTLAER 1629

Query: 1058 ENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIK-ELKETKLTFEMNIPKTEGMI--I 1114
               EE           SK  +EE++  V ++ D+++ +L   +     +  K + ++  +
Sbjct: 1630 RAAEEG---------SSKAADEEIRKQVWQEVDELRAQLDSERAALNASEKKIKSLVAEV 1680

Query: 1115 SSTIEPMSDDANNVDXXXXXXXXXXXXLK-VQEE-EEFIQERSVLQEQSAKLNTELQECY 1172
                E + D+    D            L+ V+++ EE    RS L++   +L TE+++  
Sbjct: 1681 DEVKEQLEDEILAKDKLVKAKRALEVELEEVRDQLEEEEDSRSELEDSKRRLTTEVEDIK 1740

Query: 1173 TKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRG 1232
             K       NT+L        + ++ LK +LE    + +        L S     + +  
Sbjct: 1741 KKYDAEVEQNTKLDEAKKKLTDDVDTLKKQLEDEKKKLNESERAKKRLESENEDFLAKLD 1800

Query: 1233 FEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQV 1292
             E+     ++ ++ E D +K E +L+      ++KY+ L D   + TQ E       +Q+
Sbjct: 1801 AEV-----KNRSRAEKDRKKYEKDLK------DTKYK-LNDEAATKTQTEIGAAKLEDQI 1848

Query: 1293 TSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDE-KVAF-XXXXXXXXXXXXXXXX 1350
              L++KL+ ++       +    +  +I+ LR++IEDE K+                   
Sbjct: 1849 DELRSKLEQEQAKATQADKSKKTLEGEIDNLRAQIEDEGKIKMRLEKEKRALEGELEELR 1908

Query: 1351 DLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLE 1410
            +   E +  K   EQS   +  E    +++               ++ + +++E   +LE
Sbjct: 1909 ETVEEAEDSKSEAEQSKRLVELELEDARRNLQKEIDAKEIAEDAKSNLQREIVEAKGRLE 1968

Query: 1411 LK-----DSEIYQKTHEYTI-TLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRL 1464
             +     +S+  +K  E  I  LT + D  +  + Q ++  K+IE    E   +      
Sbjct: 1969 EESIARTNSDRSRKRLEAEIDALTAQVDAEQKAKNQQIKENKKIETELKEYRKKFGESEK 2028

Query: 1465 KMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELN 1509
               +     E ++ + +  + +  +E   ++T    L K ++E++
Sbjct: 2029 TKTKEFLVVEKLETDYKRAKKEAADEQQQRLTVENDLRKHLSEIS 2073



 Score =  120 bits (289), Expect = 3e-25
 Identities = 238/1114 (21%), Positives = 457/1114 (41%), Gaps = 116/1114 (10%)

Query: 530  KSNHKLKLKQMQKTIDNF-SKVSDSNKEIVRLTEELHHLSQKVAELEE----EKGNLQLH 584
            + N + ++K+ ++ I    S ++DS  +  +L + L      V +L+     EK  L+  
Sbjct: 823  RRNFEKEIKEKEREILELKSNLTDSTTQKDKLEKSLKDTESNVLDLQRQLKAEKETLKAM 882

Query: 585  LVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKL 644
                D+    + ++  ++ +ME+  + +  A+  L++QK  + +++  L+++  E +   
Sbjct: 883  YDSKDALEAQKRELEIRVEDMESELDEKKLALENLQNQKRSVEEKVRDLEEELQEEQKLR 942

Query: 645  ADISQLQS--DQVCSEIKSVH--LEEQIDALSASKKELALVIENL-------KLDKEQLY 693
              + +L+   ++   E+K V+    + I  L   K EL   +E L         DK  L 
Sbjct: 943  NTLEKLKKKYEEELEEMKRVNDGQSDTISRLEKIKDELQKEVEELTESFSEESKDKGVLE 1002

Query: 694  GTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAE--KISELL-----AKINHE-EQS 745
             T   L+++ +D+  +L +  ++  +L  + +K+  E  ++ E L     AK+  E    
Sbjct: 1003 KTRVRLQSELDDLTVRLDSETKDKSELLRQKKKLEEELKQVQEALAAETAAKLAQEAANK 1062

Query: 746  KIQTQF-GIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGS 804
            K+Q ++  ++ K         N+E      +S++  +   +   +  R +LE+K   L +
Sbjct: 1063 KLQGEYTELNEKFNSEVTARSNVEKSKKTLESQLVAVNNELDEEKKNRDALEKKKKALDA 1122

Query: 805  YLQEKQKAYSEYTIQEDELVNRLAVLMDHD-RVVEKQLLEIEHENKELQKKNQILLEENQ 863
             L+E  K   E T  E + +  L V  + D   +  Q+ E++    +L+K    L  E  
Sbjct: 1123 MLEE-MKDQLESTGGEKKSLYDLKVKQESDMEALRNQISELQSTIAKLEKIKSTLEGEVA 1181

Query: 864  NLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKK 923
             LQ  L   Q      + K+N     E +  K +  L D  + L   T   Q L   KKK
Sbjct: 1182 RLQGELEAEQ------LAKSN----VEKQKKKVELDLEDKSAQLAEETAAKQALDKLKKK 1231

Query: 924  EIEDLEIEFNTQIESAIRDKKVLNEKYEKNIE-----YVTQLEAQLQEYKNNIENLNMNV 978
              ++L  E  TQ+  A  +K V ++   K++E        +LEA+ Q+ K  +E   + +
Sbjct: 1232 LEQELS-EVQTQLSEA-NNKNVNSDSTNKHLETSFNNLKLELEAE-QKAKQALEKKRLGL 1288

Query: 979  E-ELNKMNLELIDKHVQKQQTQSPDY-TEQYINEI-NKLNALLKQKDEEIIALNQK---I 1032
            E EL  +N +L ++  QK+  +      E+ ++E+ +++   +  K     A N+K   +
Sbjct: 1289 ESELKHVNEQLEEEKKQKESNEKRKVDLEKEVSELKDQIEEEVASKKAVTEAKNKKESEL 1348

Query: 1033 NNAQVSYMSMVSDYESKLAQFTT---KLENMEEEMQRVSKQLLDSKQHNEELQILVREQD 1089
            +  +  Y  +VS  +  + Q  T   K E +    +    QL  +++  ++ +  + E  
Sbjct: 1349 DEIKRQYADVVSSRDKSVEQLKTLQAKNEELRNTAEEAEGQLDRAERSKKKAEFDLEEAV 1408

Query: 1090 DQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEE 1149
              ++E    K+  E  + K E    S+  E   DDA NV                +  EE
Sbjct: 1409 KNLEEETAKKVKAEKAMKKAETDYRSTKSE--LDDAKNVSSEQYVQIK-------RLNEE 1459

Query: 1150 FIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTE 1209
              + RSVL+E   + N+ ++   T    LE+L  E+        +  N  K+K E+ + E
Sbjct: 1460 LSELRSVLEEADERCNSAIKAKKTAESALESLKDEI--------DAANNAKAKAERKSKE 1511

Query: 1210 NDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYE 1269
               L   VAEL  S+    D+ G    E     + +++A+      +LR +L        
Sbjct: 1512 ---LEVRVAELEESLE---DKSGTVNVEF----IRKKDAEID----DLRARLDR------ 1551

Query: 1270 QLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIED 1329
                  +S  + + +K  T +Q   L+ K+++ +  +  +      + + I  L ++++ 
Sbjct: 1552 ----ETESRIKSDEDKKNTRKQFADLEAKVEEAQREVVTIDRLKKKLESDIIDLSTQLDT 1607

Query: 1330 EKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXX 1389
            E  +                     E  S K   E+    + +E  +L+           
Sbjct: 1608 ETKSRIKIEKSKKKLEQTLAERRAAEEGSSKAADEEIRKQVWQEVDELRAQLDSERAALN 1667

Query: 1390 XXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIE 1449
                ++    A+V E+  QLE    EI  K  +          E E VR QL E     E
Sbjct: 1668 ASEKKIKSLVAEVDEVKEQLE---DEILAK-DKLVKAKRALEVELEEVRDQLEEE----E 1719

Query: 1450 DLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELN 1509
            D   E E     L  ++ +    Y     ++E+E+   ++E   K+T+ V        L 
Sbjct: 1720 DSRSELEDSKRRLTTEVEDIKKKY-----DAEVEQNTKLDEAKKKLTDDVD------TLK 1768

Query: 1510 KALEEEVAKTNEMQTALENQEIEIVTLNDEI-TNLQNMVRASSSKIQKHVSFASDTKQGR 1568
            K LE+E  K NE + A +  E E      ++   ++N  RA   + +K+     DTK   
Sbjct: 1769 KQLEDEKKKLNESERAKKRLESENEDFLAKLDAEVKNRSRAEKDR-KKYEKDLKDTKYKL 1827

Query: 1569 DEQLDNTMNKELLDAVPRAELDLAMYMLHQRDVR 1602
            +++       E+  A    ++D     L Q   +
Sbjct: 1828 NDEAATKTQTEIGAAKLEDQIDELRSKLEQEQAK 1861



 Score =  102 bits (244), Expect = 9e-20
 Identities = 181/955 (18%), Positives = 416/955 (43%), Gaps = 89/955 (9%)

Query: 659  IKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENM 718
            +K  + E++I        EL   + +    K++L  ++KD E++  D+  +L+   +   
Sbjct: 821  LKRRNFEKEIKEKEREILELKSNLTDSTTQKDKLEKSLKDTESNVLDLQRQLKAEKETLK 880

Query: 719  DLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRI 778
             + D  + + A+K  EL  ++             +++++ E+ L +EN++++    + ++
Sbjct: 881  AMYDSKDALEAQK-RELEIRVE-----------DMESELDEKKLALENLQNQKRSVEEKV 928

Query: 779  CRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVE 838
              LEE +   +  R +LE+   +    L+E ++        + + ++RL  + D    ++
Sbjct: 929  RDLEEELQEEQKLRNTLEKLKKKYEEELEEMKRVND----GQSDTISRLEKIKDE---LQ 981

Query: 839  KQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQT 898
            K++ E+     E  K   +L +    LQ  L D+    ++  E  ++++L   +  K + 
Sbjct: 982  KEVEELTESFSEESKDKGVLEKTRVRLQSELDDLTVRLDS--ETKDKSELLR-QKKKLEE 1038

Query: 899  QLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVT 958
            +L+ ++  L   T          KK ++    E N +  S +  +  + EK +K      
Sbjct: 1039 ELKQVQEALAAETAAKLAQEAANKK-LQGEYTELNEKFNSEVTARSNV-EKSKKT----- 1091

Query: 959  QLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALL 1018
             LE+QL    N ++      E+ N+  LE   K +     +  D  E    E   L  L 
Sbjct: 1092 -LESQLVAVNNELDE-----EKKNRDALEKKKKALDAMLEEMKDQLESTGGEKKSLYDLK 1145

Query: 1019 KQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHN 1078
             +++ ++ AL  +I+  Q S ++ +   +S L     +L+  E E ++++K  ++ ++  
Sbjct: 1146 VKQESDMEALRNQISELQ-STIAKLEKIKSTLEGEVARLQG-ELEAEQLAKSNVEKQKKK 1203

Query: 1079 EELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDAN----NVDXXXXX 1134
             EL +   ++  Q+ E    K   +    K E  +  S ++    +AN    N D     
Sbjct: 1204 VELDL--EDKSAQLAEETAAKQALDKLKKKLEQEL--SEVQTQLSEANNKNVNSDSTNKH 1259

Query: 1135 XXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQE 1194
                   LK++ E E  + +  L+++   L +EL+    ++ + +          V  ++
Sbjct: 1260 LETSFNNLKLELEAE-QKAKQALEKKRLGLESELKHVNEQLEEEKKQKESNEKRKVDLEK 1318

Query: 1195 QINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTE 1254
            ++++LK ++E+           VA  + +++ A +++  E+ E+ +Q+     AD   + 
Sbjct: 1319 EVSELKDQIEE----------EVAS-KKAVTEAKNKKESELDEIKRQY-----ADVVSSR 1362

Query: 1255 HELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYA 1314
             +   QL   ++K E+L    +++ +E   ++   E+  S +    D EE ++NL+E+ A
Sbjct: 1363 DKSVEQLKTLQAKNEEL----RNTAEEAEGQLDRAER--SKKKAEFDLEEAVKNLEEETA 1416

Query: 1315 DVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEEN 1374
              + + E    + E +  +                  ++  N+   ++  +S+L   +E 
Sbjct: 1417 KKV-KAEKAMKKAETDYRSTKSELDDAKNVSSEQYVQIKRLNEELSEL--RSVLEEADER 1473

Query: 1375 A----QLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTIT---- 1426
                 + KK++              N+A+AK    + +LE++ +E+ +   + + T    
Sbjct: 1474 CNSAIKAKKTAESALESLKDEIDAANNAKAKAERKSKELEVRVAELEESLEDKSGTVNVE 1533

Query: 1427 -LTQRNDEFENVRQQL-VEYEKRIEDLTYEKES--ELAILRLKMHENANHYET---MQKE 1479
             + +++ E +++R +L  E E RI+    +K +  + A L  K+ E      T   ++K+
Sbjct: 1534 FIRKKDAEIDDLRARLDRETESRIKSDEDKKNTRKQFADLEAKVEEAQREVVTIDRLKKK 1593

Query: 1480 SEIERVKLIEELNVKITESVSLNKQVAELNKAL-EEEVAKTNEMQTALENQEIEIVTLND 1538
             E + + L  +L+ +    + + K   +L + L E   A+    + A E    ++    D
Sbjct: 1594 LESDIIDLSTQLDTETKSRIKIEKSKKKLEQTLAERRAAEEGSSKAADEEIRKQVWQEVD 1653

Query: 1539 EITNLQNMVRASSSKIQKHV-SFASDTKQGRDEQLDNTMNKELLDAVPRA-ELDL 1591
            E+    +  RA+ +  +K + S  ++  + +++  D  + K+ L    RA E++L
Sbjct: 1654 ELRAQLDSERAALNASEKKIKSLVAEVDEVKEQLEDEILAKDKLVKAKRALEVEL 1708



 Score =  100 bits (239), Expect = 4e-19
 Identities = 202/1093 (18%), Positives = 433/1093 (39%), Gaps = 73/1093 (6%)

Query: 69   KRIKEHRKATAELLGRPFVPGISESLANTLKQKEILMEKIKQYKELSKRSSTTIVRXXXX 128
            K+++E  K   E L       +++  AN   Q E      K   E++ RS+   V     
Sbjct: 1034 KKLEEELKQVQEALAAETAAKLAQEAANKKLQGEYTELNEKFNSEVTARSN---VEKSKK 1090

Query: 129  XXXXXXXXXXXQLGDVTHLSNTIKEKDNALSVLQVKMKI-METT------ILDLQEKINE 181
                       +L +     + +++K  AL  +  +MK  +E+T      + DL  K+ +
Sbjct: 1091 TLESQLVAVNNELDEEKKNRDALEKKKKALDAMLEEMKDQLESTGGEKKSLYDL--KVKQ 1148

Query: 182  KDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLK 241
            +  +   +N+ +                  E  + Q     E       E + +K  L  
Sbjct: 1149 ESDMEALRNQISELQSTIAKLEKIKSTLEGEVARLQGELEAEQLAKSNVEKQKKKVEL-- 1206

Query: 242  DIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLA----- 296
            D+E K  +++    A + L+  + ++  E S++  +L +              L      
Sbjct: 1207 DLEDKSAQLAEETAAKQALDKLKKKLEQELSEVQTQLSEANNKNVNSDSTNKHLETSFNN 1266

Query: 297  -KQSIEPSCEEKTEIEEK-----GSLEIAN--MTELTKKIELLEHLNCQIRQTNKELENK 348
             K  +E   + K  +E+K       L+  N  + E  K+ E  E     + +   EL+++
Sbjct: 1267 LKLELEAEQKAKQALEKKRLGLESELKHVNEQLEEEKKQKESNEKRKVDLEKEVSELKDQ 1326

Query: 349  LATMGTESKAVS-SPSKKGSPL--ISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKN 405
            +       KAV+ + +KK S L  I R+     +S+ KS     + +  N++      + 
Sbjct: 1327 IEEEVASKKAVTEAKNKKESELDEIKRQYADVVSSRDKSVEQLKTLQAKNEELRNTAEEA 1386

Query: 406  EIAKLEMVIQSLNKDLVDKEYVIS--EKDTXXXXXXXXXXGK---DTLIAQLQLEHQQHM 460
            E  +L+   +S  K   D E  +   E++T           K   D    + +L+  +++
Sbjct: 1387 E-GQLDRAERSKKKAEFDLEEAVKNLEEETAKKVKAEKAMKKAETDYRSTKSELDDAKNV 1445

Query: 461  EGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEID 520
                 + +    E+++E+  V E+  +  N  IK           K+AE  +  L DEID
Sbjct: 1446 SSEQYVQIKRLNEELSELRSVLEEADERCNSAIK---------AKKTAESALESLKDEID 1496

Query: 521  AANKNMIKVKSNHK---LKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEE 577
            AAN    K +   K   +++ ++++++++  K    N E +R  +    +    A L+ E
Sbjct: 1497 AANNAKAKAERKSKELEVRVAELEESLED--KSGTVNVEFIRKKDA--EIDDLRARLDRE 1552

Query: 578  KGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKY 637
              +      D  + R   +D+  K+ E +    T  +    LES   DL  +L    +  
Sbjct: 1553 TESRIKSDEDKKNTRKQFADLEAKVEEAQREVVTIDRLKKKLESDIIDLSTQLDTETKSR 1612

Query: 638  DEVEDKLADISQ-LQSDQVCSEIKSVHLEEQI-DALSASKKELALVIENLKLDKEQLYGT 695
             ++E     + Q L   +   E  S   +E+I   +     EL   +++ +         
Sbjct: 1613 IKIEKSKKKLEQTLAERRAAEEGSSKAADEEIRKQVWQEVDELRAQLDSERAALNASEKK 1672

Query: 696  IKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDA 755
            IK L  + +++  +L++ I     L      +  E + E+  ++  EE S+ + +   D+
Sbjct: 1673 IKSLVAEVDEVKEQLEDEILAKDKLVKAKRALEVE-LEEVRDQLEEEEDSRSELE---DS 1728

Query: 756  KIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSE 815
            K +     +E+I+ +      +  +L+E+   + D   +L+++ +     L E ++A   
Sbjct: 1729 K-RRLTTEVEDIKKKYDAEVEQNTKLDEAKKKLTDDVDTLKKQLEDEKKKLNESERAKKR 1787

Query: 816  YTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQH 875
               + ++ + +L   + +    EK   + E + K+ + K           +I  + ++  
Sbjct: 1788 LESENEDFLAKLDAEVKNRSRAEKDRKKYEKDLKDTKYKLNDEAATKTQTEIGAAKLEDQ 1847

Query: 876  YNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQ 935
             + L  K  +     +++ K +  L     NL+    +   + ++ +KE   LE E    
Sbjct: 1848 IDELRSKLEQEQAKATQADKSKKTLEGEIDNLRAQIEDEGKIKMRLEKEKRALEGELEEL 1907

Query: 936  IESA--IRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHV 993
             E+     D K   E+ ++ +E   +LE   +  +  I+   +  +  + +  E+++   
Sbjct: 1908 RETVEEAEDSKSEAEQSKRLVE--LELEDARRNLQKEIDAKEIAEDAKSNLQREIVEAKG 1965

Query: 994  QKQQ-----TQSPDYTEQYINEINKLNALL----KQKDEEIIALNQKINNAQVSYMSMVS 1044
            + ++     T S    ++   EI+ L A +    K K+++ I  N+KI      Y     
Sbjct: 1966 RLEEESIARTNSDRSRKRLEAEIDALTAQVDAEQKAKNQQ-IKENKKIETELKEYRKKFG 2024

Query: 1045 DYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEM 1104
            + E    +    +E +E + +R  K+  D +Q    ++  +R+   +I  LK+     + 
Sbjct: 2025 ESEKTKTKEFLVVEKLETDYKRAKKEAADEQQQRLTVENDLRKHLSEISLLKDAIDKLQR 2084

Query: 1105 NIPKTEGMIISST 1117
            +  KT+  + + T
Sbjct: 2085 DHDKTKRELETET 2097



 Score = 99.1 bits (236), Expect = 9e-19
 Identities = 234/1203 (19%), Positives = 510/1203 (42%), Gaps = 113/1203 (9%)

Query: 150  TIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXX 209
            T+K   ++   L+ + + +E  + D++ +++EK   +E                      
Sbjct: 878  TLKAMYDSKDALEAQKRELEIRVEDMESELDEKKLALE--------NLQNQKRSVEEKVR 929

Query: 210  XXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISL 269
              E+  Q+  K++     ++ ++++E + + +  + +   IS LE+        + E+  
Sbjct: 930  DLEEELQEEQKLRNTLEKLKKKYEEELEEMKRVNDGQSDTISRLEK-------IKDELQK 982

Query: 270  EHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIE 329
            E  +L +   +              L  +  + +    +E ++K  L       L +K +
Sbjct: 983  EVEELTESFSEESKDKGVLEKTRVRLQSELDDLTVRLDSETKDKSEL-------LRQKKK 1035

Query: 330  LLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPW-SQ 388
            L E L         E   KLA      K     ++      S  + R+   K K    SQ
Sbjct: 1036 LEEELKQVQEALAAETAAKLAQEAANKKLQGEYTELNEKFNSEVTARSNVEKSKKTLESQ 1095

Query: 389  LSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDK-EYVISEKDTXXXXXXXXXXGKDT 447
            L +     D +KK N++ + K +  + ++ +++ D+ E    EK +            + 
Sbjct: 1096 LVAVNNELDEEKK-NRDALEKKKKALDAMLEEMKDQLESTGGEKKSLYDLKVKQESDMEA 1154

Query: 448  LIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLK- 506
            L  Q+  E Q  +    L  + +  E   E+A++Q +L+ E   ++   NV+   +K++ 
Sbjct: 1155 LRNQIS-ELQSTI--AKLEKIKSTLE--GEVARLQGELEAE---QLAKSNVEKQKKKVEL 1206

Query: 507  SAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHH 566
              E++  QL +E  AA + + K+K   + +L ++Q      +++S++N + V       H
Sbjct: 1207 DLEDKSAQLAEE-TAAKQALDKLKKKLEQELSEVQ------TQLSEANNKNVNSDSTNKH 1259

Query: 567  LSQKVAELEEEKGNLQLHLVDYDSGRM-IESDVYKKMIEMENLAETRLKAISLLESQKFD 625
            L      L+ E    Q      +  R+ +ES++  K +  E L E + K     E +K D
Sbjct: 1260 LETSFNNLKLELEAEQKAKQALEKKRLGLESEL--KHVN-EQLEEEK-KQKESNEKRKVD 1315

Query: 626  LVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENL 685
            L +E+  L+   D++E+++A      S +  +E K+   E ++D +   K++ A V+ + 
Sbjct: 1316 LEKEVSELK---DQIEEEVA------SKKAVTEAKN-KKESELDEI---KRQYADVVSSR 1362

Query: 686  KLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQS 745
                EQL    K L+   E++ N  +   +  +D  ++ +K +   + E +  +  E   
Sbjct: 1363 DKSVEQL----KTLQAKNEELRNTAEE-AEGQLDRAERSKKKAEFDLEEAVKNLEEETAK 1417

Query: 746  KIQTQFGI---DAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQL 802
            K++ +  +   +   +     +++ ++  S+   +I RL E ++   + R  LE   ++ 
Sbjct: 1418 KVKAEKAMKKAETDYRSTKSELDDAKNVSSEQYVQIKRLNEELS---ELRSVLEEADERC 1474

Query: 803  GSYLQEKQKAYSEYTIQEDEL---VNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILL 859
             S ++ K+ A S     +DE+    N  A      + +E ++ E+E E+ E  K   + +
Sbjct: 1475 NSAIKAKKTAESALESLKDEIDAANNAKAKAERKSKELEVRVAELE-ESLE-DKSGTVNV 1532

Query: 860  EENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIV 919
            E  +     + D++   +   E   ++D  +  + K   Q  DLE+ ++    E  T I 
Sbjct: 1533 EFIRKKDAEIDDLRARLDRETESRIKSDEDKKNTRK---QFADLEAKVEEAQREVVT-ID 1588

Query: 920  QKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNI--ENLNMN 977
            + KK++E   I+ +TQ+++  +  ++  EK +K +E         +E  +    E +   
Sbjct: 1589 RLKKKLESDIIDLSTQLDTETK-SRIKIEKSKKKLEQTLAERRAAEEGSSKAADEEIRKQ 1647

Query: 978  V-EELNKMNLEL---------IDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIA 1027
            V +E++++  +L          +K ++    +  +  EQ  +EI   + L+K K    + 
Sbjct: 1648 VWQEVDELRAQLDSERAALNASEKKIKSLVAEVDEVKEQLEDEILAKDKLVKAKRALEVE 1707

Query: 1028 LNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEE----EMQRVSKQLLDSKQHNEELQI 1083
            L +  +  +    S  S+ E    + TT++E++++    E+++ +K     K+  +++  
Sbjct: 1708 LEEVRDQLEEEEDSR-SELEDSKRRLTTEVEDIKKKYDAEVEQNTKLDEAKKKLTDDVDT 1766

Query: 1084 LVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLK 1143
            L ++ +D+ K+L E++   +    + E  +     E  +      D             K
Sbjct: 1767 LKKQLEDEKKKLNESERAKKRLESENEDFLAKLDAEVKNRSRAEKDRKKYEKDLKDTKYK 1826

Query: 1144 VQEEEEFIQERSV----LQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQI--- 1196
            + +E     +  +    L++Q  +L ++L++   K  Q +     L G     + QI   
Sbjct: 1827 LNDEAATKTQTEIGAAKLEDQIDELRSKLEQEQAKATQADKSKKTLEGEIDNLRAQIEDE 1886

Query: 1197 NQLKSKLEQ----LNTENDNLLSTVAELRSSISSAVDQRGFEIAELW-KQHLAQREADFQ 1251
             ++K +LE+    L  E + L  TV E   S S A   +     EL   +   Q+E D +
Sbjct: 1887 GKIKMRLEKEKRALEGELEELRETVEEAEDSKSEAEQSKRLVELELEDARRNLQKEIDAK 1946

Query: 1252 KTEHELR--VQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNL 1309
            +   + +  +Q    E+K     +S+  +  + + K +  E + +L  ++ D E+  +N 
Sbjct: 1947 EIAEDAKSNLQREIVEAKGRLEEESIARTNSDRSRKRLEAE-IDALTAQV-DAEQKAKNQ 2004

Query: 1310 QEK 1312
            Q K
Sbjct: 2005 QIK 2007



 Score = 93.9 bits (223), Expect = 3e-17
 Identities = 187/932 (20%), Positives = 384/932 (41%), Gaps = 79/932 (8%)

Query: 674  SKKELALVIEN-LKLDKEQLYGTIKDLENDKEDIMNKL--QNYIQENMDLTDKLEKMSAE 730
            + K+L   +E+ + LD+ +  G ++ +   ++   N++   ++++    L   + + + +
Sbjct: 659  NNKQLPAKLEDKVVLDQLRCNGVLEGIRITRKGFPNRIIYADFVKRYYLLAPNVPRDAED 718

Query: 731  KISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAV--M 788
                  A + H      Q +FGI  KI  R   +  IE    +  S I +  ++     +
Sbjct: 719  SQKATDAVLKHLNIDPEQYRFGI-TKIFFRAGQLARIEEAREQRISEIIKAIQAATRGWI 777

Query: 789  EDRRYSLERKADQLGSYLQEKQKAYSEYTIQED-ELVNRLAVLMDHDRVVEKQLLEIEHE 847
              + Y   R+       +Q+  +AY ++      +L ++   L+   R  EK++ E E E
Sbjct: 778  ARKVYKQAREHTVAARIIQQNLRAYIDFKSWPWWKLFSKARPLLKR-RNFEKEIKEKERE 836

Query: 848  NKELQKKNQILLEENQNLQISLSDMQQHYNALVE--KANRTDLAESESTK--YQTQLRDL 903
              EL+        +   L+ SL D + +   L    KA +  L     +K   + Q R+L
Sbjct: 837  ILELKSNLTDSTTQKDKLEKSLKDTESNVLDLQRQLKAEKETLKAMYDSKDALEAQKREL 896

Query: 904  ESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQ 963
            E  ++ +  E    + +KK  +E+L+ +    +E  +RD   L E+ ++  +    LE  
Sbjct: 897  EIRVEDMESE----LDEKKLALENLQNQ-KRSVEEKVRD---LEEELQEEQKLRNTLEKL 948

Query: 964  LQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDE 1023
             ++Y+  +E +   V +     +  ++K   + Q +  + TE +  E      L K +  
Sbjct: 949  KKKYEEELEEMK-RVNDGQSDTISRLEKIKDELQKEVEELTESFSEESKDKGVLEKTR-- 1005

Query: 1024 EIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQI 1083
              + L  ++++  V   S   D +S+L +   KLE   +++Q        +K   E    
Sbjct: 1006 --VRLQSELDDLTVRLDSETKD-KSELLRQKKKLEEELKQVQEALAAETAAKLAQEAANK 1062

Query: 1084 LVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLK 1143
             ++ +  ++ E   +++T   N+ K++      T+E      NN               +
Sbjct: 1063 KLQGEYTELNEKFNSEVTARSNVEKSK-----KTLESQLVAVNN---------------E 1102

Query: 1144 VQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKL 1203
            + EE++    R  L+++   L+  L+E      QLE+   E      +  +Q    +S +
Sbjct: 1103 LDEEKK---NRDALEKKKKALDAMLEEMKD---QLESTGGEKKSLYDLKVKQ----ESDM 1152

Query: 1204 EQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLS- 1262
            E L  +   L ST+A+L    S+   +      EL  + LA+   + QK + EL ++   
Sbjct: 1153 EALRNQISELQSTIAKLEKIKSTLEGEVARLQGELEAEQLAKSNVEKQKKKVELDLEDKS 1212

Query: 1263 ---AFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQ 1319
               A E+  +Q LD ++   ++E +++ T  Q++   NK  + +   ++L+  +    N 
Sbjct: 1213 AQLAEETAAKQALDKLKKKLEQELSEVQT--QLSEANNKNVNSDSTNKHLETSF----NN 1266

Query: 1320 IEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKK 1379
            +++     +  K A                  L  E +  K+  E+  +++ +E ++LK 
Sbjct: 1267 LKLELEAEQKAKQALEKKRLGLESELKHVNEQLEEEKKQ-KESNEKRKVDLEKEVSELKD 1325

Query: 1380 SSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQ 1439
                            N  E+++ E+  Q     S    K+ E   TL  +N+E  N  +
Sbjct: 1326 QIEEEVASKKAVTEAKNKKESELDEIKRQYADVVSS-RDKSVEQLKTLQAKNEELRNTAE 1384

Query: 1440 ----QLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQK-ESEIERVK--LIEELN 1492
                QL   E+  +   ++ E  +  L  +  +     + M+K E++    K  L +  N
Sbjct: 1385 EAEGQLDRAERSKKKAEFDLEEAVKNLEEETAKKVKAEKAMKKAETDYRSTKSELDDAKN 1444

Query: 1493 VKITESVS---LNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRA 1549
            V   + V    LN++++EL   LEE   + N    A +  E  + +L DEI +  N  +A
Sbjct: 1445 VSSEQYVQIKRLNEELSELRSVLEEADERCNSAIKAKKTAESALESLKDEI-DAANNAKA 1503

Query: 1550 SSSKIQKHVSFASDTKQGRDEQLDNTMNKELL 1581
             + +  K +       +   E    T+N E +
Sbjct: 1504 KAERKSKELEVRVAELEESLEDKSGTVNVEFI 1535


>UniRef50_Q0IVY3 Cluster: Os10g0547000 protein; n=4; Oryza sativa|Rep:
            Os10g0547000 protein - Oryza sativa subsp. japonica
            (Rice)
          Length = 1537

 Score =  122 bits (295), Expect = 6e-26
 Identities = 221/1123 (19%), Positives = 481/1123 (42%), Gaps = 75/1123 (6%)

Query: 516  NDEIDAANKNMIKVKSNHKLK--LKQMQKTIDNF-SKVSDSNKEIVRLTEELHHLSQKVA 572
            N +  A++ + +    +H  K  L+  ++TID    +     ++  +L + L  L +   
Sbjct: 284  NAQPSASDLSQLSSGVSHASKDVLENAEETIDELRGEAKMWQRKTRKLKQGLETLKKVST 343

Query: 573  ELEEEKGNLQLHLVDYDSGRMIES--DVYKKMIEMENLAETRLKA-ISLLESQKFDLVQE 629
            +  +++    L  +     R ++   +  KK    ++  ++ L+  +S+  S++  L QE
Sbjct: 344  DKSKQRSEQDLEKMWQRKTRKLKQGLETLKKECADKSKQQSELELELSISISERDSLRQE 403

Query: 630  LHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDK 689
            +  L++  +EV  +   IS+        E++   +E+ +  L  S   LA  +   +   
Sbjct: 404  IEELKRSLEEVTARQT-ISRSPRSGDAIELQK-EVEDDVQFLKESNASLATQLNKAQEAN 461

Query: 690  EQLYGTIKDLENDKEDIMNKLQNYIQENMDLTD---KLEKMSAEKISELLAKINHEEQSK 746
             +L   +++LE   E    ++ N +    DL D       +  ++  E   K++ +E   
Sbjct: 462  IELVSILQELEETIEVQRAEISN-LSHTSDLIDHEVSPNNLLIQEDVEWARKVSLKEDEI 520

Query: 747  IQTQFGIDAKIQERD--------LYIENIESELSKYKSRICRLEESIAVMEDRRYSLERK 798
            +  +  ID  +   +        +Y+E +E E    K +I  LE+  + + D    L  K
Sbjct: 521  LMLREKIDRMLHVENPNGEGSGAIYLE-LEKENDFLKVKIQELEKDCSELTDENLELIYK 579

Query: 799  ADQLGSYLQEKQKAY--SEYTIQEDELVNRLAVLMDHDRV----VEKQLLEIEHENKELQ 852
              ++    + +  +   SE    E +L +RL   + +       +E +L+    E+ EL+
Sbjct: 580  LKEVSEVAKGEDPSVPNSEEVSSEGDLSDRLTSKVKYLETKCADLELKLISFRSESSELE 639

Query: 853  KKNQILLEENQNLQISLSDMQQH---YNALVEKANRTDLAESESTKYQTQLRDLESNLKR 909
            +K Q   EE ++  + LSD++     ++AL  +   TD A  +S K +++  D   N   
Sbjct: 640  EKLQKSQEELKDRILELSDLRDKLSGFHALEMEEGDTDSA--KSYKLKSEKLDENDNKTE 697

Query: 910  ITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKN 969
            +     T+++ K++EIE L+     ++ES I   +++NEK    +E +  LE  L+E   
Sbjct: 698  LDALRSTVLL-KEQEIESLQ-HSKKEMESFI--SEIMNEK--NKLEEL--LEESLKECSI 749

Query: 970  NIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALN 1029
                L+   EEL  +    ID HV          TE    ++N L   + + + E + L+
Sbjct: 750  TAACLDEMREELLLLT-SSIDSHVSTNNVLETKITELESCKVN-LELHISKLEHENVELS 807

Query: 1030 QKINNAQVSYMSMVSDYESKLAQF---TTKLENMEEEMQRVSKQLLDSKQHNEELQILVR 1086
            + I+  +     + ++ E  + Q     + + N+++E+++V  Q ++ K   +E + L+ 
Sbjct: 808  EFISGLESQLTYLANEKELSMLQMDESRSLITNLKDELEQVEAQKVELKLQMDESRSLIT 867

Query: 1087 EQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQE 1146
               D++++++  K+  ++ + ++  +I +   E    +A  V+             +VQE
Sbjct: 868  NLKDELEQVEAQKVELKLQMDESRSLITNLKDELEQVEAQKVELKENQLESHRRLSEVQE 927

Query: 1147 EEEFIQERSV-LQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQ 1205
            + E ++  +  LQ     +  E +   T    L+    E+ G+    ++++ Q K K   
Sbjct: 928  DSEALRRSNAKLQATVDHVVEECKSLQTLTADLKKQKLEVHGYASHLEQELEQSKRKTMD 987

Query: 1206 LNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREAD------FQKTEHELRV 1259
                 ++L + ++ L+  IS        E+  ++++H    E          K E E  V
Sbjct: 988  FCKTLESLEAKLSSLQEDISLKEQSLLSELENIFQEHKEHEERIDRVHLLLNKIEKEKTV 1047

Query: 1260 QLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQ 1319
            +LS  E +   L   + S+ +E  +  +    V +++  ++    +  NL++   ++  +
Sbjct: 1048 ELSNLEREVISLTAQLSSTEEERESSTLDTIHVDNMRRSIEAARSNEDNLRKTLCEL--E 1105

Query: 1320 IEILRSEIEDEKVAFXXXXXXXXXXXXXXXXD----LRT---ENQSYKQMQEQSILNINE 1372
            ++   S+ E +++                  D    L++   E +  K   E  I +++E
Sbjct: 1106 LKSKSSDYEKQQIIEEISVLKIQVHKIAGLQDEVLTLQSSLDEAKFEKGKLEGLIQSLSE 1165

Query: 1373 ENAQLKKSSXXXXXXXXXXXXRVNDA-EAKVLELTHQLE---LKDSEIYQKTHEYTITLT 1428
            E  +LK                +N A E K +E++ Q +   L D    ++T +  +   
Sbjct: 1166 ECEELKAQKGMLTDKVSCMQDTLNAANEGKQIEISAQTKLVMLGDEPPVKETSD--VLEA 1223

Query: 1429 QRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLI 1488
            +   E   +R    EY+++I  L  ++E+E    R ++ E     +T Q + E    ++ 
Sbjct: 1224 ELKSELSIIRGANSEYQQKIYSL--QEENEDLTRRNQLMEKELDLKTSQNKDENTNKQVS 1281

Query: 1489 EELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVR 1548
             +  V + +S SL++   E N  LE  +   +E    L+ Q+     L D+++ +Q+ + 
Sbjct: 1282 LQDEVLMLQS-SLDEAKFE-NGKLEGLLQSLSEECEELKAQK---GMLTDKVSCMQDTLN 1336

Query: 1549 ASSSKIQKHVSFASDTKQGRDEQLDNTMNKELLDAVPRAELDL 1591
            A++   Q  +S  +      DE        ++L+A  ++EL +
Sbjct: 1337 AANEGKQIEISAQTKLVMLGDEP-PVKETSDVLEAELKSELSI 1378



 Score =  109 bits (261), Expect = 8e-22
 Identities = 261/1231 (21%), Positives = 502/1231 (40%), Gaps = 119/1231 (9%)

Query: 373  KSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKD 432
            K G  T  K+ +  S+  SE   QD +K   + +  KL+  +++L K+  DK    SE +
Sbjct: 332  KQGLETLKKVSTDKSKQRSE---QDLEKMWQR-KTRKLKQGLETLKKECADKSKQQSELE 387

Query: 433  TXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDE 492
                        +D+L  +++ E ++ +E  +     + +    +  ++Q++++ ++   
Sbjct: 388  LELSISISE---RDSLRQEIE-ELKRSLEEVTARQTISRSPRSGDAIELQKEVEDDVQF- 442

Query: 493  IKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSD 552
            +K+ N   L  +L  A+E   +L   +    +  I+V+      L      ID+  +VS 
Sbjct: 443  LKESNAS-LATQLNKAQEANIELVSILQELEET-IEVQRAEISNLSHTSDLIDH--EVSP 498

Query: 553  SNKEIVRLTEELHHLSQKVAELE--EEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAE 610
            +N  I    E    +S K  E+    EK +  LH V+  +G      +Y   +E+E   +
Sbjct: 499  NNLLIQEDVEWARKVSLKEDEILMLREKIDRMLH-VENPNGEG-SGAIY---LELEKEND 553

Query: 611  TRLKAISLLESQKFDLVQELHILQQKYDEVED--KLADISQLQSDQVCSEIKSVHLEEQI 668
                 I  LE    +L  E   L  K  EV +  K  D S   S++V SE       +  
Sbjct: 554  FLKVKIQELEKDCSELTDENLELIYKLKEVSEVAKGEDPSVPNSEEVSSE------GDLS 607

Query: 669  DALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMS 728
            D L++  K L     +L+L          +LE   +    +L++ I E  DL DKL    
Sbjct: 608  DRLTSKVKYLETKCADLELKLISFRSESSELEEKLQKSQEELKDRILELSDLRDKLSGFH 667

Query: 729  AEKISELLAKINHEEQSKIQTQFGIDAKIQERD--LYIENIESELSKYKSRICRLEESIA 786
            A ++ E     +  +  K++++     K+ E D    ++ + S +   +  I  L+ S  
Sbjct: 668  ALEMEE--GDTDSAKSYKLKSE-----KLDENDNKTELDALRSTVLLKEQEIESLQHSKK 720

Query: 787  VMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVL-------MDHDRVVEK 839
             ME     +  + ++L   L+E  K  S      DE+   L +L       +  + V+E 
Sbjct: 721  EMESFISEIMNEKNKLEELLEESLKECSITAACLDEMREELLLLTSSIDSHVSTNNVLET 780

Query: 840  QLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQ 899
            ++ E+E     L+     L  EN  L   +S ++     L  +   + L   ES    T 
Sbjct: 781  KITELESCKVNLELHISKLEHENVELSEFISGLESQLTYLANEKELSMLQMDESRSLITN 840

Query: 900  LRD-LES------NLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEK 952
            L+D LE        LK    E ++LI   K E+E +E +   +++  + + + L    + 
Sbjct: 841  LKDELEQVEAQKVELKLQMDESRSLITNLKDELEQVEAQ-KVELKLQMDESRSLITNLKD 899

Query: 953  NIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEIN 1012
             +E   Q+EAQ  E K N    +  + E+ + +  L   + + Q T   D+  +    + 
Sbjct: 900  ELE---QVEAQKVELKENQLESHRRLSEVQEDSEALRRSNAKLQATV--DHVVEECKSLQ 954

Query: 1013 KLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLL 1072
             L A LK++  E+      +            D+   L     KL +++E++    + LL
Sbjct: 955  TLTADLKKQKLEVHGYASHLEQELEQSKRKTMDFCKTLESLEAKLSSLQEDISLKEQSLL 1014

Query: 1073 --------DSKQHNEE-------LQILVREQDDQIKELKETKLTFEMNIPKTEGMIISST 1117
                    + K+H E        L  + +E+  ++  L+   ++    +  TE    SST
Sbjct: 1015 SELENIFQEHKEHEERIDRVHLLLNKIEKEKTVELSNLEREVISLTAQLSSTEEERESST 1074

Query: 1118 IEPMSDD---------ANNVDXXXXXXXXXXXXLKVQ--EEEEFIQERSVLQEQSAKLNT 1166
            ++ +  D          +N D             K    E+++ I+E SVL+ Q  K+  
Sbjct: 1075 LDTIHVDNMRRSIEAARSNEDNLRKTLCELELKSKSSDYEKQQIIEEISVLKIQVHKI-A 1133

Query: 1167 ELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISS 1226
             LQ+   +++ L++   E        +  I  L  + E+L  +   L   V+ ++ ++++
Sbjct: 1134 GLQD---EVLTLQSSLDEAKFEKGKLEGLIQSLSEECEELKAQKGMLTDKVSCMQDTLNA 1190

Query: 1227 AVDQRGFEIAELWKQHLAQREADFQKT----EHELRVQLSAFE---SKYEQLLDSVQSST 1279
            A + +  EI+   K  +   E   ++T    E EL+ +LS      S+Y+Q + S+Q   
Sbjct: 1191 ANEGKQIEISAQTKLVMLGDEPPVKETSDVLEAELKSELSIIRGANSEYQQKIYSLQEEN 1250

Query: 1280 QEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXX 1339
            ++ T +   ME+   L+   Q+K+E+      K   + +++ +L+S +++ K        
Sbjct: 1251 EDLTRRNQLMEKELDLKTS-QNKDEN----TNKQVSLQDEVLMLQSSLDEAKFE-NGKLE 1304

Query: 1340 XXXXXXXXXXXDLRTEN--QSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVND 1397
                       +L+ +    + K    Q  LN   E  Q++ S+                
Sbjct: 1305 GLLQSLSEECEELKAQKGMLTDKVSCMQDTLNAANEGKQIEISAQTKLVMLGDEPPVKET 1364

Query: 1398 AEAKVLELTHQLEL---KDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYE 1454
            ++    EL  +L +    +SE  QK H    +L + N++    R QL+  EK ++  T +
Sbjct: 1365 SDVLEAELKSELSIIRGANSEYQQKIH----SLQKENEDLTR-RNQLM--EKELDLKTSQ 1417

Query: 1455 KESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQV-AELNKALE 1513
             + E      K   +AN           E    I+ L  ++ E++  NK    +L   + 
Sbjct: 1418 NKDENT---NKQGNDANENGDSPVNEVPELQSKIQLLETRLAEALEENKLYRGQLKSPMP 1474

Query: 1514 EEVAKTNEMQTALENQEIEIVTLNDEITNLQ 1544
            E  + + +     EN + +I  L  E+ ++Q
Sbjct: 1475 EGKSASKD---GKENDDDKISQLESELKDMQ 1502



 Score = 92.3 bits (219), Expect = 1e-16
 Identities = 179/862 (20%), Positives = 373/862 (43%), Gaps = 54/862 (6%)

Query: 504  KLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNF-SKVSDSNKEIVRLTE 562
            KLKS +        E+DA    ++ +K      L+  +K +++F S++ +   ++  L E
Sbjct: 683  KLKSEKLDENDNKTELDALRSTVL-LKEQEIESLQHSKKEMESFISEIMNEKNKLEELLE 741

Query: 563  E-LHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLES 621
            E L   S   A L+E +  L L     DS     + +  K+ E+E+        IS LE 
Sbjct: 742  ESLKECSITAACLDEMREELLLLTSSIDSHVSTNNVLETKITELESCKVNLELHISKLEH 801

Query: 622  QKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALV 681
            +  +L + +  L+ +   + ++  ++S LQ D+  S I   +L+++++ + A K EL L 
Sbjct: 802  ENVELSEFISGLESQLTYLANE-KELSMLQMDESRSLI--TNLKDELEQVEAQKVELKLQ 858

Query: 682  IENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINH 741
            ++  +     L   ++ +E  K ++  ++        +L D+LE++ A+K+ EL  K N 
Sbjct: 859  MDESRSLITNLKDELEQVEAQKVELKLQMDESRSLITNLKDELEQVEAQKV-EL--KENQ 915

Query: 742  EEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQ 801
             E  +  ++   D++   R      +++ +         L+   A ++ ++  +   A  
Sbjct: 916  LESHRRLSEVQEDSEALRRSN--AKLQATVDHVVEECKSLQTLTADLKKQKLEVHGYASH 973

Query: 802  LGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLL-EIEH---ENKELQKK--- 854
            L   L++ ++   ++    + L  +L+ L +   + E+ LL E+E+   E+KE +++   
Sbjct: 974  LEQELEQSKRKTMDFCKTLESLEAKLSSLQEDISLKEQSLLSELENIFQEHKEHEERIDR 1033

Query: 855  -NQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESEST----KYQTQLRDLESNLKR 909
             + +L +  +   + LS++++   +L  + + T+     ST          R +E+    
Sbjct: 1034 VHLLLNKIEKEKTVELSNLEREVISLTAQLSSTEEERESSTLDTIHVDNMRRSIEAARSN 1093

Query: 910  ITHEHQTLI-VQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYK 968
              +  +TL  ++ K +  D E +   QI   I   K+   K     + V  L++ L E K
Sbjct: 1094 EDNLRKTLCELELKSKSSDYEKQ---QIIEEISVLKIQVHKIAGLQDEVLTLQSSLDEAK 1150

Query: 969  NN-------IENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQK 1021
                     I++L+   EEL      L DK    Q T +     + I EI+    L+   
Sbjct: 1151 FEKGKLEGLIQSLSEECEELKAQKGMLTDKVSCMQDTLNAANEGKQI-EISAQTKLVMLG 1209

Query: 1022 DEEIIALNQKINNAQV-SYMSMV----SDYESKLAQFTTKLENMEEEMQRVSKQL-LDSK 1075
            DE  +     +  A++ S +S++    S+Y+ K+     + E++    Q + K+L L + 
Sbjct: 1210 DEPPVKETSDVLEAELKSELSIIRGANSEYQQKIYSLQEENEDLTRRNQLMEKELDLKTS 1269

Query: 1076 QHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXX 1135
            Q+ +E         D++  L+ +    +    K EG++  S  E   +            
Sbjct: 1270 QNKDENTNKQVSLQDEVLMLQSSLDEAKFENGKLEGLL-QSLSEECEELKAQKGMLTDKV 1328

Query: 1136 XXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELT---GHDVVN 1192
                  L    E + I+  +  Q +   L  E     T  +    L +EL+   G +   
Sbjct: 1329 SCMQDTLNAANEGKQIEISA--QTKLVMLGDEPPVKETSDVLEAELKSELSIIRGANSEY 1386

Query: 1193 QEQINQLKSKLEQLNTENDNLLSTVAELRSSISSA--VDQRGFEIAELWKQ---HLAQRE 1247
            Q++I+ L+ + E L T  + L+    +L++S +     +++G +  E        + + +
Sbjct: 1387 QQKIHSLQKENEDL-TRRNQLMEKELDLKTSQNKDENTNKQGNDANENGDSPVNEVPELQ 1445

Query: 1248 ADFQKTEHELRVQLSAFESKYEQLLDSV-QSSTQEETNKIVTMEQVTSLQNKLQDKEEHL 1306
            +  Q  E  L   L   +    QL   + +  +  +  K    ++++ L+++L+D +E L
Sbjct: 1446 SKIQLLETRLAEALEENKLYRGQLKSPMPEGKSASKDGKENDDDKISQLESELKDMQERL 1505

Query: 1307 RNLQEKYADVINQIEILRSEIE 1328
             N+  +YA+V  Q E L  E++
Sbjct: 1506 LNVSLQYAEVEAQREELVMELK 1527



 Score = 84.6 bits (200), Expect = 2e-14
 Identities = 229/1171 (19%), Positives = 480/1171 (40%), Gaps = 92/1171 (7%)

Query: 147  LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXX 206
            L     +K    S L++++ I  +    L+++I E  + +E      T            
Sbjct: 372  LKKECADKSKQQSELELELSISISERDSLRQEIEELKRSLEEVTARQTISRSPRSGDAIE 431

Query: 207  XXXXXEDTKQQMTKMQENFI-----AMEA--EWKDEKQRLLKDIESKDVRISSLEEANKL 259
                 ED  Q + +   +       A EA  E     Q L + IE +   IS+L   + L
Sbjct: 432  LQKEVEDDVQFLKESNASLATQLNKAQEANIELVSILQELEETIEVQRAEISNLSHTSDL 491

Query: 260  LEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCE-EKTEIEEKGS--L 316
            ++    E+S  +  + +++E               + ++ I+     E    E  G+  L
Sbjct: 492  ID---HEVSPNNLLIQEDVEWARKVSLKEDEIL--MLREKIDRMLHVENPNGEGSGAIYL 546

Query: 317  EIANMTELTK-KIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSG 375
            E+    +  K KI+ LE    ++   N EL  KL  +   +K    PS   S  +S +  
Sbjct: 547  ELEKENDFLKVKIQELEKDCSELTDENLELIYKLKEVSEVAKG-EDPSVPNSEEVSSEG- 604

Query: 376  RNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISE-KDTX 434
             + + ++ S    L ++  + +      ++E ++LE  +Q   ++L D+   +S+ +D  
Sbjct: 605  -DLSDRLTSKVKYLETKCADLELKLISFRSESSELEEKLQKSQEELKDRILELSDLRDKL 663

Query: 435  XXXXXXXXXGKDTLIAQ-LQLEHQQHMEGPSLIHVGTNTEDV----NEIAKVQEQLKQEL 489
                       DT  A+  +L+ ++  E  +   +      V     EI  +Q   K+E+
Sbjct: 664  SGFHALEMEEGDTDSAKSYKLKSEKLDENDNKTELDALRSTVLLKEQEIESLQHS-KKEM 722

Query: 490  NDEIKDV-NVKDLIEKL--KSAEE-QIT-----QLNDEIDAANKNMIK-VKSNHKL--KL 537
               I ++ N K+ +E+L  +S +E  IT     ++ +E+     ++   V +N+ L  K+
Sbjct: 723  ESFISEIMNEKNKLEELLEESLKECSITAACLDEMREELLLLTSSIDSHVSTNNVLETKI 782

Query: 538  KQMQKTIDNFS-KVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDY-------- 588
             +++    N    +S    E V L+E +  L  ++  L  EK    L + +         
Sbjct: 783  TELESCKVNLELHISKLEHENVELSEFISGLESQLTYLANEKELSMLQMDESRSLITNLK 842

Query: 589  DSGRMIESDVYKKMIEMENLAE--TRLK-AISLLESQKFDLVQELH----ILQQKYDEVE 641
            D    +E+   +  ++M+      T LK  +  +E+QK +L  ++     ++    DE+E
Sbjct: 843  DELEQVEAQKVELKLQMDESRSLITNLKDELEQVEAQKVELKLQMDESRSLITNLKDELE 902

Query: 642  DKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLEN 701
               A   +L+ +Q+ S  +   ++E  +AL  S  +L   ++++  + + L     DL+ 
Sbjct: 903  QVEAQKVELKENQLESHRRLSEVQEDSEALRRSNAKLQATVDHVVEECKSLQTLTADLKK 962

Query: 702  DKEDIMNKLQNYIQE-------NMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGID 754
             K ++     +  QE        MD    LE + A K+S L   I+ +EQS +     I 
Sbjct: 963  QKLEVHGYASHLEQELEQSKRKTMDFCKTLESLEA-KLSSLQEDISLKEQSLLSELENIF 1021

Query: 755  AKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYS 814
             + +E +  I+ +   L+K +      E+++ +    R  +   A QL S  +E++ +  
Sbjct: 1022 QEHKEHEERIDRVHLLLNKIEK-----EKTVELSNLEREVISLTA-QLSSTEEERESSTL 1075

Query: 815  EYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQ 874
            + TI  D +   +     ++  + K L E+E ++K    + Q ++EE   L+I +  +  
Sbjct: 1076 D-TIHVDNMRRSIEAARSNEDNLRKTLCELELKSKSSDYEKQQIIEEISVLKIQVHKIAG 1134

Query: 875  HYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFN- 933
              + ++   +  D A+ E  K +  ++ L    + +  + + ++  K   ++D     N 
Sbjct: 1135 LQDEVLTLQSSLDEAKFEKGKLEGLIQSLSEECEELKAQ-KGMLTDKVSCMQDTLNAANE 1193

Query: 934  -TQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQ-----------EYKNNIENLNMNVEEL 981
              QIE + + K V+        E    LEA+L+           EY+  I +L    E+L
Sbjct: 1194 GKQIEISAQTKLVMLGDEPPVKETSDVLEAELKSELSIIRGANSEYQQKIYSLQEENEDL 1253

Query: 982  NKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMS 1041
             + N +L++K +  + +Q+ D        +     +L+   +E    N K+     S   
Sbjct: 1254 TRRN-QLMEKELDLKTSQNKDENTNKQVSLQDEVLMLQSSLDEAKFENGKLEGLLQSLSE 1312

Query: 1042 MVSDYESKLAQFTTKLENMEEEMQRVS--KQLLDSKQHNEELQILVREQD-DQIKELKET 1098
               + +++    T K+  M++ +   +  KQ+  S Q   +L +L  E    +  ++ E 
Sbjct: 1313 ECEELKAQKGMLTDKVSCMQDTLNAANEGKQIEISAQ--TKLVMLGDEPPVKETSDVLEA 1370

Query: 1099 KLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQER-SVL 1157
            +L  E++I +         I  +  +  ++                Q ++E   ++ +  
Sbjct: 1371 ELKSELSIIRGANSEYQQKIHSLQKENEDLTRRNQLMEKELDLKTSQNKDENTNKQGNDA 1430

Query: 1158 QEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTE-NDNLLST 1216
             E       E+ E  +KI  LET   E    + + + Q+     + +  + +  +N    
Sbjct: 1431 NENGDSPVNEVPELQSKIQLLETRLAEALEENKLYRGQLKSPMPEGKSASKDGKENDDDK 1490

Query: 1217 VAELRSSISSAVDQRGFEIAELWKQHLAQRE 1247
            +++L S +   + +R   ++  + +  AQRE
Sbjct: 1491 ISQLESELKD-MQERLLNVSLQYAEVEAQRE 1520


>UniRef50_A0DSK6 Cluster: Chromosome undetermined scaffold_61, whole
            genome shotgun sequence; n=1; Paramecium tetraurelia|Rep:
            Chromosome undetermined scaffold_61, whole genome shotgun
            sequence - Paramecium tetraurelia
          Length = 1266

 Score =  122 bits (295), Expect = 6e-26
 Identities = 218/976 (22%), Positives = 419/976 (42%), Gaps = 103/976 (10%)

Query: 403  NKNEIA-KLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHME 461
            NK E+   L+     LN+ +    Y+  +++            KD  I  L  +  +   
Sbjct: 242  NKEELKLHLQQQTSKLNEQINKNNYIEQQRNQEIQNLQFQVQVKDKQIQNLLSQIGEQRN 301

Query: 462  GPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDA 521
              +L     + E + ++  +  QL QE++  + +  +  L ++ K  ++ +TQL  E + 
Sbjct: 302  KTNL----QDQERLQQLENLNNQLVQEIS--VLEGELAKLKQQAKDFQK-VTQLEKENEN 354

Query: 522  ANKNMIKVK-SNH--KLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEK 578
                +   K  NH  K +LK +Q+ I+     + +    ++L +E+ + ++ ++EL+EE 
Sbjct: 355  LQMIIQDQKVQNHDTKQQLKLLQEEINQLKGQNQNKSNTIQLEQEIKYYARLLSELQEEN 414

Query: 579  GNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYD 638
            G LQ  L+D++    I  ++       E L + + +   L+E Q   ++Q    L+Q+ +
Sbjct: 415  GKLQNQLLDFEE---INEELLLLRRNNEELQQQQTEDSKLVEDQSLKIIQ----LEQELN 467

Query: 639  EVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKD 698
             +        Q Q + +  E     L +QI+ L+   KE     E L      L   +  
Sbjct: 468  HLR------QQNQQESIIKE-----LNKQIEQLNQINKERE--AEILYQQDLLLKQNVNS 514

Query: 699  LENDKEDIMNKLQN--YIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAK 756
             E DK     K +N  Y  +N  LT++  K S  +I E   K + E   K+QT      +
Sbjct: 515  KEFDKLITEQKAENKEYQIQNNQLTNQELKKSQLEI-ESYNKKHEENLQKMQTLEKDKQQ 573

Query: 757  IQER-DLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSE 815
            IQ   D +I+ I+ + ++  S   +LE   A +  +R  L+ +  +L     ++Q   S 
Sbjct: 574  IQNNFDHHIKEIQKKDAEKLSNFTQLENENAKLYQQRNKLQERIGELEEAANQQQIELSN 633

Query: 816  YTIQEDELVNRLAV----LMDHDRVVEK-QLLEIEHEN---------KELQKKNQILLEE 861
                 +EL+N+L      L+D++  V+K   L  E +N         K+L+ +NQ L  +
Sbjct: 634  LKKDNEELLNQLETQNSHLIDNNEQVQKVNFLNQEQQNIINEKELFIKQLESQNQELELK 693

Query: 862  NQNLQISLSDMQQHYNAL--VEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIV 919
             + L I + + Q+        ++ N  +L   E    + + ++LE+ L +   +    I 
Sbjct: 694  VEKLSIEIQEQQEQQQNFENQQEGNDQELLLQEIDLLKQKNQELENQLNQQIDDDAEEID 753

Query: 920  QKKKEIEDLEIEFN------TQIESAIRDKKVLNEKYEKNIEYVTQL----EAQLQEYKN 969
            + +KE+   +  +N       ++++   D +   E+ ++ IE + Q+    + Q  E K 
Sbjct: 754  KLEKELYHQKQNYNELKINLEELQTGKEDSQKRAEEKDEEIERLKQIVFEYQEQQDESKK 813

Query: 970  NIENLNMNVEEL------NK---MNLE--LIDKHVQKQQTQSPDYTEQYIN-EINKLNAL 1017
             IE+L  N +EL      N+    +LE  +++K  Q +  Q       +IN E  KL   
Sbjct: 814  QIEDLYNNQKELAIELSENQKIIQDLESTIVEKEEQIKNLQQQTPQNDFINQETEKLMFQ 873

Query: 1018 LKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQH 1077
            +KQ  E+I   NQ I    +   + +++ +S+L Q   ++  M  + Q +  +L    + 
Sbjct: 874  VKQMQEQIEDQNQTI----LQLENELNNKDSQLKQKLYEIRQMSLQTQLIEIKL---TRE 926

Query: 1078 NEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDA--NNVDXXXXXX 1135
             E+L+    E   Q  + +   L F+    ++E  I  S IEP +      N D      
Sbjct: 927  IEDLKNKAFEAIQQRVKYENELLKFQQ---ESEKQIELSRIEPNNQQCTYENEDLSHIAL 983

Query: 1136 XXXXXXLKVQEE--EEFIQERSVLQEQSAKLNTELQECYTKIIQLETL-NTELTGHDVVN 1192
                     QEE  + F + +  ++ +  +   ELQE    IIQ+E     EL   D   
Sbjct: 984  GKAPEAEDNQEEYSQSFEEYQEEIEVKDQEKQEELQEPQINIIQIEEAPQIEL---DKEE 1040

Query: 1193 QEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQK 1252
             E++ +L +  +Q   EN +      EL+  I+  +    ++  EL ++   Q   + QK
Sbjct: 1041 NEEVFELCNAQKQ--EENSD-----QELKEPIAEIIQDDEYQQIELDEKPKDQFGIN-QK 1092

Query: 1253 TEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEK 1312
             E +  ++L   E K  Q++   Q     +       E+V  L N   D+E+    L++ 
Sbjct: 1093 YETQNLLELEEPEIKIVQMIQQPQIELDSQKK---NQEEVFELGN-AADEEDDEEELKQV 1148

Query: 1313 YADVINQIEILRSEIE 1328
              +++     ++ E++
Sbjct: 1149 VCEIVQNPPNIQIELD 1164



 Score =  116 bits (279), Expect = 5e-24
 Identities = 246/1180 (20%), Positives = 504/1180 (42%), Gaps = 126/1180 (10%)

Query: 414  IQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTE 473
            +  L K + D ++ I  +D+           + + I Q  LE  +       I      E
Sbjct: 74   VSYLKKKIEDLQFRIDSQDSKLKAREKEIVYQQSQIKQFVLEINEIQ-----IIEDNYKE 128

Query: 474  DVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQ---ITQLNDEIDAANKNMIKVK 530
            +++ + K   Q K++    +K+   +   +  +S +EQ     +  + I+   + M  ++
Sbjct: 129  EISVLNKEISQWKEKYFANLKEYQFRQAQQSRQSQQEQGLMRKKYEEIIEQQQREMESIE 188

Query: 531  SNHKLKLKQMQKTIDNFSKVSDSNKE----IVRLTE---ELHHLSQKVAELEEEKGNLQL 583
               + + + + + ++  +K    N E    I++L +   E H L +K+  LE  K  L+L
Sbjct: 189  IRFENERENLYRALELQNKTQSKNNELNELIIQLEDKESETHKLKEKIQVLETNKEELKL 248

Query: 584  HLVDYDS--GRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYD-EV 640
            HL    S     I  + Y +    + +   + + + + + Q  +L+ ++   + K + + 
Sbjct: 249  HLQQQTSKLNEQINKNNYIEQQRNQEIQNLQFQ-VQVKDKQIQNLLSQIGEQRNKTNLQD 307

Query: 641  EDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLE 700
            +++L  +  L ++Q+  EI SV LE ++  L    K+   V + L+ + E L   I+D +
Sbjct: 308  QERLQQLENL-NNQLVQEI-SV-LEGELAKLKQQAKDFQKVTQ-LEKENENLQMIIQDQK 363

Query: 701  ---NDKEDIMNKLQNYIQ----ENMDLTDKLE-KMSAEKISELLAKINHEEQSKIQTQFG 752
               +D +  +  LQ  I     +N + ++ ++ +   +  + LL+++  EE  K+Q Q  
Sbjct: 364  VQNHDTKQQLKLLQEEINQLKGQNQNKSNTIQLEQEIKYYARLLSEL-QEENGKLQNQLL 422

Query: 753  IDAKIQERDLYIENIESELSKYKSRICRL--EESIAVME-DRRYSLERKADQLGSYLQEK 809
               +I E  L +     EL + ++   +L  ++S+ +++ ++  +  R+ +Q  S ++E 
Sbjct: 423  DFEEINEELLLLRRNNEELQQQQTEDSKLVEDQSLKIIQLEQELNHLRQQNQQESIIKEL 482

Query: 810  QKAYSEYT----IQEDELVNRLAVLMD---HDRVVEKQLLEIEHENKELQKKNQILLEEN 862
             K   +       +E E++ +  +L+    + +  +K + E + ENKE Q +N  L   N
Sbjct: 483  NKQIEQLNQINKEREAEILYQQDLLLKQNVNSKEFDKLITEQKAENKEYQIQNNQL--TN 540

Query: 863  QNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKK 922
            Q L+ S  +++  YN   E+ N   +   E  K Q Q  + + ++K I    Q    +K 
Sbjct: 541  QELKKSQLEIES-YNKKHEE-NLQKMQTLEKDKQQIQ-NNFDHHIKEI----QKKDAEKL 593

Query: 923  KEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELN 982
                 LE E N ++    + +  L E+  +  E   Q + +L   K + E L   + +L 
Sbjct: 594  SNFTQLENE-NAKL---YQQRNKLQERIGELEEAANQQQIELSNLKKDNEEL---LNQLE 646

Query: 983  KMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSM 1042
              N  LID + Q Q+    +  +Q  N IN+    +KQ + +   L  K+    +     
Sbjct: 647  TQNSHLIDNNEQVQKVNFLNQEQQ--NIINEKELFIKQLESQNQELELKVEKLSIE---- 700

Query: 1043 VSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQ-DDQIKELKETKLT 1101
            + + + +   F  + E  ++E+      LL  KQ N+EL+  + +Q DD  +E+   KL 
Sbjct: 701  IQEQQEQQQNFENQQEGNDQELLLQEIDLL--KQKNQELENQLNQQIDDDAEEI--DKLE 756

Query: 1102 FEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQS 1161
             E+   K     +   +E +     +               K +E E   Q     QEQ 
Sbjct: 757  KELYHQKQNYNELKINLEELQTGKEDSQKRAEE--------KDEEIERLKQIVFEYQEQQ 808

Query: 1162 AKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELR 1221
             +   ++++ Y    Q E L  EL+     NQ+ I  L+S + +   +  NL     +  
Sbjct: 809  DESKKQIEDLYNN--QKE-LAIELS----ENQKIIQDLESTIVEKEEQIKNLQQQTPQ-N 860

Query: 1222 SSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQE 1281
              I+   ++  F++ ++ +Q   Q +   Q  E+EL  + S  + K   L +  Q S Q 
Sbjct: 861  DFINQETEKLMFQVKQMQEQIEDQNQTILQ-LENELNNKDSQLKQK---LYEIRQMSLQT 916

Query: 1282 ETNKIVTMEQVTSLQNK----LQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXX 1337
            +  +I    ++  L+NK    +Q + ++   L +   +   QIE+ R E  +++  +   
Sbjct: 917  QLIEIKLTREIEDLKNKAFEAIQQRVKYENELLKFQQESEKQIELSRIEPNNQQCTYENE 976

Query: 1338 XXXXXXXXXXXXXDLRTE--NQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRV 1395
                         +   E  +QS+++ QE+  +   E+  +L++              ++
Sbjct: 977  DLSHIALGKAPEAEDNQEEYSQSFEEYQEEIEVKDQEKQEELQEP-------------QI 1023

Query: 1396 NDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEK 1455
            N  +   +E   Q+EL D E  ++  E      Q  +  + +++ + E    I+D  Y+ 
Sbjct: 1024 NIIQ---IEEAPQIEL-DKEENEEVFELCNAQKQEENSDQELKEPIAEI---IQDDEYQ- 1075

Query: 1456 ESELAILRLKMHENANHYETMQ----KESEIERVKLIEELNVKITESVSLNKQVAELNKA 1511
            + EL             YET      +E EI+ V++I++  +++       ++V EL  A
Sbjct: 1076 QIELDEKPKDQFGINQKYETQNLLELEEPEIKIVQMIQQPQIELDSQKKNQEEVFELGNA 1135

Query: 1512 LEEEVAKTNEMQTALE------NQEIEIVTLNDEITNLQN 1545
             +EE  +    Q   E      N +IE+   ++ I + QN
Sbjct: 1136 ADEEDDEEELKQVVCEIVQNPPNIQIELDQGDNNIPHQQN 1175



 Score =  110 bits (265), Expect = 3e-22
 Identities = 193/906 (21%), Positives = 394/906 (43%), Gaps = 85/906 (9%)

Query: 743  EQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEE--SIAVMEDRRYSLERKAD 800
            ++ K+  +  + +  Q+    I   ++++++ +SR   ++   S    E    S E    
Sbjct: 2    DRKKLLFENNLKSNCQDLMAGIRETKAKVNEIRSRCDSIKRGSSKQPFEVNNKSYEISTK 61

Query: 801  QLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKK-NQI-L 858
              GS++  K    S    + ++L  R+       +  EK+++  + + K+   + N+I +
Sbjct: 62   TSGSFINLKDNDVSYLKKKIEDLQFRIDSQDSKLKAREKEIVYQQSQIKQFVLEINEIQI 121

Query: 859  LEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLI 918
            +E+N   +IS+  + +  +   EK    +L E +  + Q Q R  +     +  +++ +I
Sbjct: 122  IEDNYKEEISV--LNKEISQWKEKYF-ANLKEYQFRQAQ-QSRQSQQEQGLMRKKYEEII 177

Query: 919  VQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNV 978
             Q+++E+E +EI F  + E+  R  ++ N+   KN E + +L  QL++ ++    L   +
Sbjct: 178  EQQQREMESIEIRFENERENLYRALELQNKTQSKNNE-LNELIIQLEDKESETHKLKEKI 236

Query: 979  EELNKMNLELIDKHVQKQ------QTQSPDYTEQYIN-EINKLNALLKQKDEEIIALNQK 1031
            + L + N E +  H+Q+Q      Q    +Y EQ  N EI  L   ++ KD++I  L  +
Sbjct: 237  QVL-ETNKEELKLHLQQQTSKLNEQINKNNYIEQQRNQEIQNLQFQVQVKDKQIQNLLSQ 295

Query: 1032 I----NNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQ------HNEEL 1081
            I    N   +     +   E+   Q   ++  +E E+ ++ +Q  D ++       NE L
Sbjct: 296  IGEQRNKTNLQDQERLQQLENLNNQLVQEISVLEGELAKLKQQAKDFQKVTQLEKENENL 355

Query: 1082 QILVREQDDQIKELKETK--LTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXX 1139
            Q+++++Q  Q  + K+    L  E+N  K +    S+TI+ +  +               
Sbjct: 356  QMIIQDQKVQNHDTKQQLKLLQEEINQLKGQNQNKSNTIQ-LEQEIKYYARLLSELQEEN 414

Query: 1140 XXLKVQ----EE--EEFI---QERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDV 1190
              L+ Q    EE  EE +   +    LQ+Q  + +  +++   KIIQLE    EL     
Sbjct: 415  GKLQNQLLDFEEINEELLLLRRNNEELQQQQTEDSKLVEDQSLKIIQLEQ---ELNHLRQ 471

Query: 1191 VNQEQ--INQLKSKLEQLNTENDNLLSTVAELRSSI-SSAVDQRGFE--IAELWKQHLAQ 1245
             NQ++  I +L  ++EQLN  N    + +   +  +    V+ + F+  I E   ++   
Sbjct: 472  QNQQESIIKELNKQIEQLNQINKEREAEILYQQDLLLKQNVNSKEFDKLITEQKAENKEY 531

Query: 1246 READFQKTEHELR---VQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQ-VTSLQNKLQD 1301
            +  + Q T  EL+   +++ ++  K+E+ L  +Q+  +++       +  +  +Q K  +
Sbjct: 532  QIQNNQLTNQELKKSQLEIESYNKKHEENLQKMQTLEKDKQQIQNNFDHHIKEIQKKDAE 591

Query: 1302 KEEHLRNLQEKYADVINQIEILRS---EIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQ- 1357
            K  +   L+ + A +  Q   L+    E+E+                      L T+N  
Sbjct: 592  KLSNFTQLENENAKLYQQRNKLQERIGELEEAANQQQIELSNLKKDNEELLNQLETQNSH 651

Query: 1358 ---SYKQMQEQSILNINEENA---------QLKKSSXXXXXXXXXXXXRVNDAEAKVLEL 1405
               + +Q+Q+ + LN  ++N          QL+  +             + + + +    
Sbjct: 652  LIDNNEQVQKVNFLNQEQQNIINEKELFIKQLESQNQELELKVEKLSIEIQEQQEQQQNF 711

Query: 1406 THQLELKDSEIYQKTHEYTITLTQRNDEFEN-VRQQLVEYEKRIEDLT---YEKESELAI 1461
             +Q E  D E+  +  +    L Q+N E EN + QQ+ +  + I+ L    Y ++     
Sbjct: 712  ENQQEGNDQELLLQEIDL---LKQKNQELENQLNQQIDDDAEEIDKLEKELYHQKQNYNE 768

Query: 1462 LRLKMHENANHYETMQK-----ESEIERVK-LIEELNVKITESVSLNKQVAELNKALEEE 1515
            L++ + E     E  QK     + EIER+K ++ E   +  ES    KQ+ +L    +E 
Sbjct: 769  LKINLEELQTGKEDSQKRAEEKDEEIERLKQIVFEYQEQQDES---KKQIEDLYNNQKEL 825

Query: 1516 VAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNT 1575
              + +E Q  +++ E  IV   ++I NLQ     +    Q+        KQ   EQ+++ 
Sbjct: 826  AIELSENQKIIQDLESTIVEKEEQIKNLQQQTPQNDFINQETEKLMFQVKQ-MQEQIED- 883

Query: 1576 MNKELL 1581
             N+ +L
Sbjct: 884  QNQTIL 889



 Score = 50.8 bits (116), Expect = 3e-04
 Identities = 139/709 (19%), Positives = 292/709 (41%), Gaps = 68/709 (9%)

Query: 220  KMQENFIAMEAEWKDEKQ------RLLKDIESKDVR----ISSLEEANKLLEAARFEISL 269
            K +EN   M+   KD++Q        +K+I+ KD       + LE  N  L   R ++  
Sbjct: 556  KHEENLQKMQTLEKDKQQIQNNFDHHIKEIQKKDAEKLSNFTQLENENAKLYQQRNKLQE 615

Query: 270  EHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIE 329
               +L +   Q              L  Q    +       E+   +   N  E    I 
Sbjct: 616  RIGELEEAANQQQIELSNLKKDNEELLNQLETQNSHLIDNNEQVQKVNFLNQ-EQQNIIN 674

Query: 330  LLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTA------SKMK 383
              E    Q+   N+ELE K+  +  E   +    ++     +++ G +          +K
Sbjct: 675  EKELFIKQLESQNQELELKVEKLSIE---IQEQQEQQQNFENQQEGNDQELLLQEIDLLK 731

Query: 384  SPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXX 443
                +L ++ LNQ  D   +  EI KLE  +    ++  + +  + E  T          
Sbjct: 732  QKNQELENQ-LNQQIDD--DAEEIDKLEKELYHQKQNYNELKINLEELQTGKEDSQKRAE 788

Query: 444  GKDTLIAQLQ---LEHQQHM-EGPSLIHVGTNTE-----DVNEIAKVQEQLKQ---ELND 491
             KD  I +L+    E+Q+   E    I    N +     +++E  K+ + L+    E  +
Sbjct: 789  EKDEEIERLKQIVFEYQEQQDESKKQIEDLYNNQKELAIELSENQKIIQDLESTIVEKEE 848

Query: 492  EIKDVNVK----DLI-EKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDN 546
            +IK++  +    D I ++ +    Q+ Q+ ++I+  N+ ++++++    K  Q+++ +  
Sbjct: 849  QIKNLQQQTPQNDFINQETEKLMFQVKQMQEQIEDQNQTILQLENELNNKDSQLKQKLYE 908

Query: 547  FSKVSDSNKEI-VRLTEELHHLSQKVAELEEEKGNLQLHLVDY--DSGRMIESDVYKKMI 603
              ++S   + I ++LT E+  L  K  E  +++   +  L+ +  +S + IE    +   
Sbjct: 909  IRQMSLQTQLIEIKLTREIEDLKNKAFEAIQQRVKYENELLKFQQESEKQIELSRIEPNN 968

Query: 604  EMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCS-EIKSV 662
            +        L  I+L ++ + +  QE +   Q ++E ++++    Q + +++   +I  +
Sbjct: 969  QQCTYENEDLSHIALGKAPEAEDNQEEY--SQSFEEYQEEIEVKDQEKQEELQEPQINII 1026

Query: 663  HLEE--QIDALSASKKELALVIENLKLDK---EQLYGTIKDLENDKEDIMNKLQNYIQEN 717
             +EE  QI+      +E+  +    K ++   ++L   I ++  D E    +L    ++ 
Sbjct: 1027 QIEEAPQIELDKEENEEVFELCNAQKQEENSDQELKEPIAEIIQDDEYQQIELDEKPKDQ 1086

Query: 718  MDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENI---ESELSKY 774
              +  K E  +  ++ E   KI    Q   Q +     K QE    + N    E +  + 
Sbjct: 1087 FGINQKYETQNLLELEEPEIKIVQMIQQP-QIELDSQKKNQEEVFELGNAADEEDDEEEL 1145

Query: 775  KSRICRLEES---IAVMEDRR-YSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVL 830
            K  +C + ++   I +  D+   ++  + +Q  +   E  K   E    E +L+N L + 
Sbjct: 1146 KQVVCEIVQNPPNIQIELDQGDNNIPHQQNQTNNLGVENPK---EKPKVEKDLLNLLDLQ 1202

Query: 831  MDHDRVVEKQL---LEIEHENKELQKKNQILLEENQNLQISLSDMQQHY 876
                 +V+ +    LE++ EN EL++ +Q L EE   ++I L    Q +
Sbjct: 1203 EPVTEIVQVEQYVQLELDQENFELKEPDQQLEEE---VEIQLDKKPQEF 1248


>UniRef50_A4QRL5 Cluster: Putative uncharacterized protein; n=1;
            Magnaporthe grisea|Rep: Putative uncharacterized protein
            - Magnaporthe grisea (Rice blast fungus) (Pyricularia
            grisea)
          Length = 1645

 Score =  122 bits (295), Expect = 6e-26
 Identities = 229/1141 (20%), Positives = 469/1141 (41%), Gaps = 125/1141 (10%)

Query: 497  NVKDLIEKLK-SAEEQITQLNDEIDAANKNMIK--VKSNHKLKLKQ--MQKTIDNFSK-V 550
            NV D IEK     + +I  L D +  A     +  +K N +LK+    M++ +  + K +
Sbjct: 180  NVIDRIEKENFGLKLKIHFLEDALRRAGPGFSEAALKENTELKVDSVTMKRELHRYKKHL 239

Query: 551  SDSNKEIVRLTEELHHLSQKVAELEEEKGN------LQLHLVDYDSGRMIESDVYKKMIE 604
            + + K++    +++  +  K  + +  +G       LQ  L + D+G     D+ +K+ +
Sbjct: 240  TSAEKDLEAYRQQILEMQDKFKKRQANEGQRLEIERLQQALEEKDAGL---EDLQQKLDQ 296

Query: 605  MENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHL 664
             E   +   K    +   + D   +  ++ Q  DE+ED    I   +     S+ + V L
Sbjct: 297  GEKELDRIEKLQDEIGDLEADNRAKDQLIGQHEDEIEDLKLRIQAAEDKAKDSQRRMVEL 356

Query: 665  EEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKL 724
            EE+  A S+   E    IE+L+ D       ++ L+N+ E+  +KLQ+ +    D  D+ 
Sbjct: 357  EEKAQA-SSKLAEAKEAIEDLEAD-------VRRLQNELEEYKDKLQDAV----DAKDRA 404

Query: 725  EKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEES 784
            E    E++ E +A         + T+ G+  +++E+   I  ++ E+   +S +  +   
Sbjct: 405  EG-DLEELQEEMAN------KSVVTK-GLSRQVEEK---IARLQDEVEDARSNLATVNNR 453

Query: 785  IAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEI 844
                E+    L+RK  +     +  ++     + + DEL   L    DH  +++ +   +
Sbjct: 454  YQDKENEVEDLKRKLKESRQERETFERENRSLSAEVDELQGDLRSANDHKSLLQTRHDAL 513

Query: 845  EHENKELQKKNQILLEENQNLQISLSDMQQH---YNALVEKANRTDL--AESESTKYQTQ 899
              E+  LQ+    L  +   L+ SL   +QH       V + NRT++    SE +  Q +
Sbjct: 514  TKESASLQRDVSRLQRDTAALEASLEQEKQHALQIERTVREQNRTEINRLRSEISDLQAR 573

Query: 900  LRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDK-KVLNEKYEKNIEYVT 958
             R+ E + +  T   +    Q K E+E L+ + +  +++ IR+K  + +  +EK    + 
Sbjct: 574  AREAEEDRQHATQSDRISRDQLKDEVERLKDDIS-DLQAQIREKDNMYDNDHEKWETEIR 632

Query: 959  QLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQ---TQSPDYTEQYINEINKLN 1015
             LEA+    +     L   +++L      L  K  + Q    T++  + ++      ++ 
Sbjct: 633  NLEAERDRAEERANGLQRTIDKLRATEGALSTKEAKLQHIIDTETERHRKEEAVLSRQVE 692

Query: 1016 ALLKQKDE----------EIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQ 1065
            +L K  D           E+ ++ +++  AQV Y S V   E    +       +EE+ +
Sbjct: 693  SLQKTLDSRQTMLEDLRIELSSVREQLRQAQVDYQSEVDKVEGLEDELELLQVELEEQSE 752

Query: 1066 RVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDA 1125
            + S+ L  +K+  E L    R+Q    +E   T +     +        S  I+ + D  
Sbjct: 753  KASRDLEQAKRECENL----RQQLQSAQESAATSVRQSNTVSHEVARHNSEHIQRLKDQL 808

Query: 1126 NNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKI----IQLETL 1181
                                +  +  +E+ +LQEQ A +NTEL      +     + E+L
Sbjct: 809  AE---------------STTKFSKTTKEKQLLQEQLAGVNTELYSVRASLAESQAERESL 853

Query: 1182 NTEL-----TGHD--VVNQEQIN------QLKSKLEQLNTENDNLLSTVAELRSSISSA- 1227
             ++L     +G D  VVNQE ++      +L S++ +L  EN +L   + ++ + +  A 
Sbjct: 854  ESDLRLAKQSGQDVHVVNQELVDLRTTKTKLDSEVRRLREENKSLAGRLRQVEAELQDAK 913

Query: 1228 VDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQ-SSTQEETNKI 1286
            +  +   + +  +  L   ++        L  Q  +  S+  ++   ++    Q++  K 
Sbjct: 914  LHGQDTALLDQERMDLLTAKSKLDGDVRRLGDQNRSLTSRLREVETELRLLKQQDDHTKQ 973

Query: 1287 VTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXX 1346
            + +++V  +  K +  E  LR ++E+   + ++    ++EIE+E V              
Sbjct: 974  LELQRVDIISAKSR-LENELRRVKEENVVLTSE----KAEIENELVRVSKNQGEDTLDLN 1028

Query: 1347 XXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELT 1406
                 LRT     K   E  +  + E+N QL++S             R    E +   LT
Sbjct: 1029 FERITLRTA----KNKLETELRCLKEKNRQLEESLLELERQLDEENERAAQEEER---LT 1081

Query: 1407 HQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLT----YEKESELAIL 1462
            H++    +++ Q T     T ++R  +   + +++  YE R+   T     E  S+L+IL
Sbjct: 1082 HEILELQAKLRQSTDTQAQTASRR--KIRELERRIDNYEARLAITTNIVDVEGNSDLSIL 1139

Query: 1463 RLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKAL----EEEVAK 1518
            R  +   A   E    E E      + +L  +I++   +  + AE+ + L    +     
Sbjct: 1140 RRDI-TTARQKERDFAEREAAHKSTVRDLKRQISDLERVVHE-AEMQRLLASPADARTPS 1197

Query: 1519 TNEMQTALENQEIEIV-----TLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLD 1573
            T + + A    ++ +       L   +   +    A   ++Q  +    D     ++QLD
Sbjct: 1198 TRKSELAQLRHQLTLAHQVGQDLKQALREAERDADAVKDELQARIGDLEDQAASLEQQLD 1257

Query: 1574 N 1574
            +
Sbjct: 1258 D 1258



 Score =  100 bits (240), Expect = 3e-19
 Identities = 171/880 (19%), Positives = 386/880 (43%), Gaps = 78/880 (8%)

Query: 483  EQLKQELNDEIKDVNVKDLIEKLKSAE---EQITQLNDEI---DAANKNMIKVKSNHKLK 536
            E+L+Q L +  KD  ++DL +KL   E   ++I +L DEI   +A N+   ++   H+ +
Sbjct: 274  ERLQQALEE--KDAGLEDLQQKLDQGEKELDRIEKLQDEIGDLEADNRAKDQLIGQHEDE 331

Query: 537  LKQMQKTIDNF-SKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIE 595
            ++ ++  I     K  DS + +V L EE    S K+AE +E   +L+  +    +     
Sbjct: 332  IEDLKLRIQAAEDKAKDSQRRMVEL-EEKAQASSKLAEAKEAIEDLEADVRRLQNELEEY 390

Query: 596  SDVYKKMIEMENLAETRLKAISLLESQKFDLVQEL-HILQQK----YDEVEDKLADISQL 650
             D  +  ++ ++ AE  L+ +    + K  + + L   +++K     DEVED  ++++ +
Sbjct: 391  KDKLQDAVDAKDRAEGDLEELQEEMANKSVVTKGLSRQVEEKIARLQDEVEDARSNLATV 450

Query: 651  QSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKL 710
             +     E +   L+ ++      ++       +L  + ++L G ++   + K  +  + 
Sbjct: 451  NNRYQDKENEVEDLKRKLKESRQERETFERENRSLSAEVDELQGDLRSANDHKSLLQTRH 510

Query: 711  QNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERD-LYIENIES 769
                +E+  L   + ++  +  + L A +  E+Q  +Q    I+  ++E++   I  + S
Sbjct: 511  DALTKESASLQRDVSRLQRD-TAALEASLEQEKQHALQ----IERTVREQNRTEINRLRS 565

Query: 770  ELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAV 829
            E+S  ++R    E      EDR+++ +  +D++      + +   E    +D++ +  A 
Sbjct: 566  EISDLQARAREAE------EDRQHATQ--SDRI-----SRDQLKDEVERLKDDISDLQAQ 612

Query: 830  LMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNAL-VEKANRTDL 888
            + + D + +    + E E + L+ +     E    LQ ++  ++    AL  ++A    +
Sbjct: 613  IREKDNMYDNDHEKWETEIRNLEAERDRAEERANGLQRTIDKLRATEGALSTKEAKLQHI 672

Query: 889  AESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNE 948
             ++E+ +++ +    E+ L R     Q  +  ++  +EDL IE ++ +   +R  +V   
Sbjct: 673  IDTETERHRKE----EAVLSRQVESLQKTLDSRQTMLEDLRIELSS-VREQLRQAQV--- 724

Query: 949  KYEKNIEYVTQLEAQLQ----EYKNNIENLNMNVEELNK--MNLELIDKHVQKQQTQSPD 1002
             Y+  ++ V  LE +L+    E +   E  + ++E+  +   NL    +  Q+    S  
Sbjct: 725  DYQSEVDKVEGLEDELELLQVELEEQSEKASRDLEQAKRECENLRQQLQSAQESAATSVR 784

Query: 1003 YTEQYINEINKLNA--LLKQKDE--EIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLE 1058
             +    +E+ + N+  + + KD+  E      K    +      ++   ++L      L 
Sbjct: 785  QSNTVSHEVARHNSEHIQRLKDQLAESTTKFSKTTKEKQLLQEQLAGVNTELYSVRASLA 844

Query: 1059 NMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTI 1118
              + E + +   L  +KQ  +++ ++ +E  D ++  K TKL  E+   + E   ++  +
Sbjct: 845  ESQAERESLESDLRLAKQSGQDVHVVNQELVD-LRTTK-TKLDSEVRRLREENKSLAGRL 902

Query: 1119 EPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQ-------EQSAKLNTELQEC 1171
              +  +  +              L  QE  + +  +S L        +Q+  L + L+E 
Sbjct: 903  RQVEAELQD-----AKLHGQDTALLDQERMDLLTAKSKLDGDVRRLGDQNRSLTSRLREV 957

Query: 1172 YTKIIQLE-----TLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISS 1226
             T++  L+     T   EL   D+++ +  ++L+++L ++  EN  L S  AE+ + +  
Sbjct: 958  ETELRLLKQQDDHTKQLELQRVDIISAK--SRLENELRRVKEENVVLTSEKAEIENELVR 1015

Query: 1227 AVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKI 1286
                +G +  +L  + +  R A   K E ELR  L     + E+ L  ++    EE  + 
Sbjct: 1016 VSKNQGEDTLDLNFERITLRTAK-NKLETELRC-LKEKNRQLEESLLELERQLDEENERA 1073

Query: 1287 VTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSE 1326
               E+   L +++ + +  LR   +  A   ++ +I   E
Sbjct: 1074 AQEEE--RLTHEILELQAKLRQSTDTQAQTASRRKIRELE 1111



 Score = 64.1 bits (149), Expect = 3e-08
 Identities = 187/1167 (16%), Positives = 472/1167 (40%), Gaps = 116/1167 (9%)

Query: 213  DTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHS 272
            + K+ +  ++ +   ++ E ++ K +L   +++KD     LEE                 
Sbjct: 368  EAKEAIEDLEADVRRLQNELEEYKDKLQDAVDAKDRAEGDLEE----------------- 410

Query: 273  KLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEE-KGSLEIANMTELTKKIELL 331
             L +E+                L++Q  E     + E+E+ + +L   N     K+ E +
Sbjct: 411  -LQEEM-------ANKSVVTKGLSRQVEEKIARLQDEVEDARSNLATVNNRYQDKENE-V 461

Query: 332  EHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSPWSQLSS 391
            E L  +++++ +E E    T   E++++S+   +       +S  +  S +++    L+ 
Sbjct: 462  EDLKRKLKESRQERE----TFERENRSLSAEVDELQG--DLRSANDHKSLLQTRHDALTK 515

Query: 392  ETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQ 451
            E+ +   D    + + A LE  ++   +  +  E  + E++                 A+
Sbjct: 516  ESASLQRDVSRLQRDTAALEASLEQEKQHALQIERTVREQNRTEINRLRSEISDLQARAR 575

Query: 452  LQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQ 511
               E +QH          T ++ ++     ++QLK E+ + +KD ++ DL  +++  +  
Sbjct: 576  EAEEDRQH---------ATQSDRIS-----RDQLKDEV-ERLKD-DISDLQAQIREKDNM 619

Query: 512  ITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKV 571
                +++ +   +N+   +   + +   +Q+TID            +R TE    LS K 
Sbjct: 620  YDNDHEKWETEIRNLEAERDRAEERANGLQRTIDK-----------LRATEGA--LSTKE 666

Query: 572  AELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELH 631
            A+L+        H++D ++ R  + +      ++E+L +T     ++LE  + +L     
Sbjct: 667  AKLQ--------HIIDTETERHRKEEAVLSR-QVESLQKTLDSRQTMLEDLRIELSSVRE 717

Query: 632  ILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQ 691
             L+Q   + + ++  +  L+ +    E+  V LEEQ +  S   ++     ENL+   + 
Sbjct: 718  QLRQAQVDYQSEVDKVEGLEDE---LELLQVELEEQSEKASRDLEQAKRECENLRQQLQS 774

Query: 692  LYGTIKDLENDKEDIMNKLQNYIQENMD-LTDKLEKMSAEKISELL--AKINHEEQSKIQ 748
               +          + +++  +  E++  L D+L + S  K S+     ++  E+ + + 
Sbjct: 775  AQESAATSVRQSNTVSHEVARHNSEHIQRLKDQLAE-STTKFSKTTKEKQLLQEQLAGVN 833

Query: 749  TQ-FGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQ 807
            T+ + + A + E     E++ES+L   K     +      + D R + + K D     L+
Sbjct: 834  TELYSVRASLAESQAERESLESDLRLAKQSGQDVHVVNQELVDLR-TTKTKLDSEVRRLR 892

Query: 808  EKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQI 867
            E+ K+ +    Q +  +    +      +++++ +++     +L    + L ++N++L  
Sbjct: 893  EENKSLAGRLRQVEAELQDAKLHGQDTALLDQERMDLLTAKSKLDGDVRRLGDQNRSLTS 952

Query: 868  SLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIED 927
             L +++     L ++ + T   E +     +    LE+ L+R+  E+  ++  +K EIE+
Sbjct: 953  RLREVETELRLLKQQDDHTKQLELQRVDIISAKSRLENELRRVKEEN-VVLTSEKAEIEN 1011

Query: 928  LEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLE 987
                     E     K    +  + N E +T L     + +  +  L     +L +  LE
Sbjct: 1012 ---------ELVRVSKNQGEDTLDLNFERIT-LRTAKNKLETELRCLKEKNRQLEESLLE 1061

Query: 988  LIDKHVQKQQTQSPDYTEQYINEINKLNALLKQK--DEEIIALNQKINNAQVSYMSMVSD 1045
            L ++ + ++  ++    E+  +EI +L A L+Q    +   A  +KI   +      + +
Sbjct: 1062 L-ERQLDEENERAAQEEERLTHEILELQAKLRQSTDTQAQTASRRKIRELE----RRIDN 1116

Query: 1046 YESKLAQFTTKLENME--EEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFE 1103
            YE++LA  TT + ++E   ++  + + +  ++Q   +           +++LK      E
Sbjct: 1117 YEARLA-ITTNIVDVEGNSDLSILRRDITTARQKERDFAEREAAHKSTVRDLKRQISDLE 1175

Query: 1104 MNIPKTE-GMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQER-----SVL 1157
              + + E   +++S  +  +      +               Q+ ++ ++E      +V 
Sbjct: 1176 RVVHEAEMQRLLASPADARTPSTRKSELAQLRHQLTLAHQVGQDLKQALREAERDADAVK 1235

Query: 1158 QEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTV 1217
             E  A++     +  +   QL+            ++  + + + K+E+   E D   + +
Sbjct: 1236 DELQARIGDLEDQAASLEQQLDDARAAAEEAAAASETALVKYRGKVERYRRERDQYAAAL 1295

Query: 1218 AELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQS 1277
             E++ +   +      +++        +   D      + +++  +FE +  +     + 
Sbjct: 1296 EEMQHTDHGSALTARTDVSN-------EERRDLHGMLRKAQIEADSFEREVREHKALAEE 1348

Query: 1278 STQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXX 1337
             ++ +    + +E+V   +   + + E +R  ++  A  ++  E++R++ E E       
Sbjct: 1349 LSKAQETLCLKLERVRGERAVYRKEAERMR--RDLRAVELSNAELVRAKDEAEGALVANA 1406

Query: 1338 XXXXXXXXXXXXXDLRTENQSYKQMQE 1364
                            +EN++ + ++E
Sbjct: 1407 LILASRDAAAIAPPANSENKAAETVKE 1433


>UniRef50_UPI00015B5411 Cluster: PREDICTED: similar to SD07366p; n=1;
            Nasonia vitripennis|Rep: PREDICTED: similar to SD07366p -
            Nasonia vitripennis
          Length = 1535

 Score =  122 bits (294), Expect = 8e-26
 Identities = 159/853 (18%), Positives = 360/853 (42%), Gaps = 53/853 (6%)

Query: 492  EIKDVNVKDLIEKLKSAEEQITQLND-EIDAAN-KNMIKVKSNHKLKLKQMQKTIDNFSK 549
            ++ +  ++  +E+ K  +E I  + + ++D  N +  +K+  ++  +L+     +     
Sbjct: 569  DVLESELRVSLERCKGLDENIELIEELKLDLENARRELKIALSNNKRLENSLTILQETKN 628

Query: 550  VSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLA 609
              D++ E++   +E     Q  A+L+       L   D D+   +   + K   E ++L 
Sbjct: 629  EVDADNEVLSREKE-----QLEADLKLLSSGSDLKKSDGDALAELREQLKKSKEEKDDLE 683

Query: 610  ETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQL--QSDQVCSEIKSVHLEEQ 667
                     + + + +L Q L  L+    E+E    D  +L  ++ ++  +      +E 
Sbjct: 684  YD-------IRNMRNELDQSLEQLEANRAEIEKLQLDNERLAKENGKLLDQFSETQ-KEN 735

Query: 668  IDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKM 727
            +D +     E+ L+ + L  +K++L  T++ L + +E I+  L+N   EN  L  +  K+
Sbjct: 736  LDKVDLLNTEMTLLQQELDGNKDELEKTMRYLSDMEEKILT-LKN---ENERLNVEASKI 791

Query: 728  SAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAV 787
               +I  L  K   EE+S   T+  +DA +++    +  +E ++S  +S   RL++ +  
Sbjct: 792  KENEIEFLKLKEQLEERSLDHTKEELDAALKK----LSELEEKVSMLESENKRLQDELIR 847

Query: 788  MEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHE 847
              D    ++ +  +L   ++EKQK   E    E+E  N    L    +  E  +  +E E
Sbjct: 848  TSD----VDSENKRLVEAIEEKQK---EIAKNEEEAANVTTKL----KCTENYISSLEDE 896

Query: 848  NKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNL 907
            ++ L+ K   + +EN++ +  + +++Q   +  E+  +    +  S+ YQT+L  L+   
Sbjct: 897  SQILESKLAQVDQENESAKKEIEELRQQLES--ERRQKEADGKELSSTYQTELDKLKGEN 954

Query: 908  KRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEY 967
            +R+  E   L+V+K+    +     + Q+     ++  L ++  +  + +  L+A + + 
Sbjct: 955  ERLKSELDKLLVEKRDVEVNTRASSDAQVSLTEEERSQLLDQLSEKFKEIENLKATISKD 1014

Query: 968  KNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTE--QYINEINKLNALLKQKDEEI 1025
            K++ +     VE L+++     ++ ++   T      E  + +  + + +    Q   EI
Sbjct: 1015 KDSAQMARETVENLSQLISSKDNELIKLNATVDMFRNERDEVVKLVQEKHNESLQYHAEI 1074

Query: 1026 IALNQKINNAQVSYMSMVSDYESKLAQFTTKLENM---EEEMQRVSKQLL---DSKQHNE 1079
              L Q I++   +    +++ ++ LA    K   +   + E+Q V ++L    +S  H E
Sbjct: 1075 QRLTQLISDQTANLQKAIAEKDATLASLQEKESQLLWTQNELQVVKQRLQNIEESNNHGE 1134

Query: 1080 ELQILVREQ-DDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXX 1138
               I         +  L+E     E  I + +  I    ++    +A + +         
Sbjct: 1135 RCGIAEHTLLSKHVSTLEEKSKAMEAAILQDQSNI--RYLQEQLTEAQSKETIALKEVDR 1192

Query: 1139 XXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQ 1198
                 V+ E  + +E    +E    L   L +   K   L+  +T  T   V   +Q+  
Sbjct: 1193 LRNHLVEMEANYTEEALQSEEIQRTLQARLMQAEEK---LKNSSTMYTSASVRANQQVET 1249

Query: 1199 LKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELR 1258
            L+ +L  +  + D+L + ++     + S        +  + +Q    +E D Q    +LR
Sbjct: 1250 LQQQLALIVQQRDDLQNKISSAEDKVLS-YSASLTNLQLVLEQFQRDKEKDIQAATEKLR 1308

Query: 1259 VQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVIN 1318
            V+L     K ++L+  + S  ++       +   + L  +L+ K E +  L ++   +  
Sbjct: 1309 VELQQSYKKQDELVSEITSLKEQLAEAKECLRAASRLTEQLEKKSERIELLNQEVNRLTE 1368

Query: 1319 QIEILRSEIEDEK 1331
             +      IE+ K
Sbjct: 1369 LVNTADQRIEEAK 1381



 Score =  111 bits (266), Expect = 2e-22
 Identities = 245/1241 (19%), Positives = 514/1241 (41%), Gaps = 104/1241 (8%)

Query: 338  IRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTA-SKMKSPWSQLSSE--TL 394
            IR     LEN+   +   ++   S           + GR+ + +K++     L +E  +L
Sbjct: 196  IRSALMALENESEQLQGSAEKTDSVGYDAEGKSRNEKGRDESEAKLRRRVEDLEAENQSL 255

Query: 395  NQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQL 454
            +Q  ++ ++K     +E V+ SL ++L  K + +               GK   + Q Q 
Sbjct: 256  SQSIEE-LDKQNAESIERVL-SLKEELQKKHHSLQGAYEQLYVEYNQALGKIENLQQQQ- 312

Query: 455  EHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQ 514
            + QQ  + P L     N   ++   +   QLK +   EI+        E   S E++  +
Sbjct: 313  QQQQQQQKPELSKA-PNKSSLDTAVQTLAQLKLDKETEIRPAKEDKQTEISTSKEDKEVE 371

Query: 515  LN----DEIDAAN--KNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIV----RLTEEL 564
            ++    D+ D A+  K +  +  N  L+          F  V+    E+      L  +L
Sbjct: 372  VDLKPEDQQDLASELKKVNDILKNAPLEPSNEHLNDSVFVAVARQFVELKWKKETLERKL 431

Query: 565  HHLSQKVAELEEEKGNLQLHLVDYDSG-RMIESDVYKKMIEMENLAETRLKAISLLESQK 623
               S+++ E +E + +LQ+   D  +    +  +V      + ++ E   + ++ LE++ 
Sbjct: 432  TEQSRQLKETQELRDSLQIDCEDMQTNIESLVMEVQHLKSNLPSIPEASEERVASLETET 491

Query: 624  FDLVQELHILQQKYDEVEDKLADI-SQLQSD------QVCSEIKSVHLEEQIDALSASKK 676
              L  E+  L++   ++  +L  I + ++ D      ++ + I+S+  E+     S S K
Sbjct: 492  ESLQAEILALRKSKADMSSELKAIKAAIREDGGGGGVELATRIESLLAEQN---KSKSSK 548

Query: 677  ELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELL 736
            + A +++    +   L   I  LE++    + + +  + EN++L ++L K+  E     L
Sbjct: 549  DPAELLQATLDENTALRRRIDVLESELRVSLERCKG-LDENIELIEEL-KLDLENARREL 606

Query: 737  AKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLE 796
             KI      +++    I   +QE    ++     LS+ K +   LE  + ++       +
Sbjct: 607  -KIALSNNKRLENSLTI---LQETKNEVDADNEVLSREKEQ---LEADLKLLSSGSDLKK 659

Query: 797  RKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQ 856
               D L    ++ +K+  E    E ++ N    L      +E    EIE    +LQ  N+
Sbjct: 660  SDGDALAELREQLKKSKEEKDDLEYDIRNMRNELDQSLEQLEANRAEIE----KLQLDNE 715

Query: 857  ILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLK---RITHE 913
             L +EN  L    S+ Q+      E  ++ DL  +E T  Q +L   +  L+   R   +
Sbjct: 716  RLAKENGKLLDQFSETQK------ENLDKVDLLNTEMTLLQQELDGNKDELEKTMRYLSD 769

Query: 914  HQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQ-LEAQLQEYKNNIE 972
             +  I+  K E E L +E +   E+ I   K+  +  E+++++  + L+A L++    + 
Sbjct: 770  MEEKILTLKNENERLNVEASKIKENEIEFLKLKEQLEERSLDHTKEELDAALKK----LS 825

Query: 973  NLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKI 1032
             L   V  L   N  L D+ ++     S +  ++ +  I +    + + +EE   +  K+
Sbjct: 826  ELEEKVSMLESENKRLQDELIRTSDVDSEN--KRLVEAIEEKQKEIAKNEEEAANVTTKL 883

Query: 1033 NNAQVSYMSMVSD----YESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNE----ELQIL 1084
               + +Y+S + D     ESKLAQ   + E+ ++E++ + +QL   ++  E    EL   
Sbjct: 884  KCTE-NYISSLEDESQILESKLAQVDQENESAKKEIEELRQQLESERRQKEADGKELSST 942

Query: 1085 VREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKV 1144
             + + D++K   E +L  E++    E   +       SD   ++              K 
Sbjct: 943  YQTELDKLKGENE-RLKSELDKLLVEKRDVEVNTRASSDAQVSLTEEERSQLLDQLSEKF 1001

Query: 1145 QEEEEFIQERSVLQEQSAKLNTELQECYTKII-----QLETLNTELTGHDVVNQEQINQL 1199
            +E E  ++      + SA++  E  E  +++I     +L  LN  +        E +  +
Sbjct: 1002 KEIEN-LKATISKDKDSAQMARETVENLSQLISSKDNELIKLNATVDMFRNERDEVVKLV 1060

Query: 1200 KSKLE---QLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHE 1256
            + K     Q + E   L   +++  +++  A+ ++   +A L      ++E+    T++E
Sbjct: 1061 QEKHNESLQYHAEIQRLTQLISDQTANLQKAIAEKDATLASL-----QEKESQLLWTQNE 1115

Query: 1257 LRV---QLSAFESKY---------EQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEE 1304
            L+V   +L   E            E  L S   ST EE +K +    +   Q+ ++  +E
Sbjct: 1116 LQVVKQRLQNIEESNNHGERCGIAEHTLLSKHVSTLEEKSKAMEAA-ILQDQSNIRYLQE 1174

Query: 1305 HLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQ--- 1361
             L   Q K    + +++ LR+ + + +  +                 L    +  K    
Sbjct: 1175 QLTEAQSKETIALKEVDRLRNHLVEMEANYTEEALQSEEIQRTLQARLMQAEEKLKNSST 1234

Query: 1362 MQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDS--EIYQK 1419
            M   + +  N++   L++              +++ AE KVL  +  L       E +Q+
Sbjct: 1235 MYTSASVRANQQVETLQQQLALIVQQRDDLQNKISSAEDKVLSYSASLTNLQLVLEQFQR 1294

Query: 1420 THEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKE 1479
              E  I         E ++Q   + ++ + ++T  KE +LA  +  +   +   E ++K+
Sbjct: 1295 DKEKDIQAATEKLRVE-LQQSYKKQDELVSEITSLKE-QLAEAKECLRAASRLTEQLEKK 1352

Query: 1480 SEIERVKLIEELNVKITESV-SLNKQVAELNKALEEEVAKT 1519
            S  ER++L+ +   ++TE V + ++++ E  K+ E +V ++
Sbjct: 1353 S--ERIELLNQEVNRLTELVNTADQRIEEAKKSGEGKVDRS 1391



 Score =  107 bits (256), Expect = 3e-21
 Identities = 210/1131 (18%), Positives = 467/1131 (41%), Gaps = 78/1131 (6%)

Query: 461  EGPSLIHVGTNTEDVNEIAKVQ--EQLKQELNDEIKDVNVKDL--IEKLKSAEEQITQLN 516
            EG S    G +  +     +V+  E   Q L+  I++++ ++   IE++ S +E++ + +
Sbjct: 225  EGKSRNEKGRDESEAKLRRRVEDLEAENQSLSQSIEELDKQNAESIERVLSLKEELQKKH 284

Query: 517  DEIDAANKNMIKVKSNHKL-KLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELE 575
              +  A + +  V+ N  L K++ +Q+      +              L    Q +A+L+
Sbjct: 285  HSLQGAYEQLY-VEYNQALGKIENLQQQQQQQQQQQKPELSKAPNKSSLDTAVQTLAQLK 343

Query: 576  EEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQ 635
             +K   ++     D    I +    K +E++   E +    S  E +K + + +   L+ 
Sbjct: 344  LDK-ETEIRPAKEDKQTEISTSKEDKEVEVDLKPEDQQDLAS--ELKKVNDILKNAPLEP 400

Query: 636  KYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGT 695
              + + D +      Q  ++  + K   LE ++   S   KE   + ++L++D E +   
Sbjct: 401  SNEHLNDSVFVAVARQFVEL--KWKKETLERKLTEQSRQLKETQELRDSLQIDCEDMQTN 458

Query: 696  IKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDA 755
            I+ L  + + + + L +  + + +    LE  +    +E+LA    +     + +  I A
Sbjct: 459  IESLVMEVQHLKSNLPSIPEASEERVASLETETESLQAEILALRKSKADMSSELK-AIKA 517

Query: 756  KIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSE 815
             I+E D     +E       +RI    ES+   +++  S +  A+ L + L E       
Sbjct: 518  AIRE-DGGGGGVE-----LATRI----ESLLAEQNKSKSSKDPAELLQATLDENTALRRR 567

Query: 816  YTIQEDEL---VNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDM 872
              + E EL   + R   L ++  ++E+  L++E+  +EL+    I L  N+ L+ SL+ +
Sbjct: 568  IDVLESELRVSLERCKGLDENIELIEELKLDLENARRELK----IALSNNKRLENSLTIL 623

Query: 873  QQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEF 932
            Q+  N  V+  N     E E  +   +L    S+LK+   +    + ++ K+ ++ + + 
Sbjct: 624  QETKNE-VDADNEVLSREKEQLEADLKLLSSGSDLKKSDGDALAELREQLKKSKEEKDDL 682

Query: 933  NTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKH 992
               I +   +     E+ E N   + +L+   +        L     E  K NL+ +D  
Sbjct: 683  EYDIRNMRNELDQSLEQLEANRAEIEKLQLDNERLAKENGKLLDQFSETQKENLDKVDL- 741

Query: 993  VQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQ 1052
            +  + T      +   +E+ K    L   +E+I+ L  +     V   S + + E +  +
Sbjct: 742  LNTEMTLLQQELDGNKDELEKTMRYLSDMEEKILTLKNENERLNVE-ASKIKENEIEFLK 800

Query: 1053 FTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGM 1112
               +LE  E  +    ++L  + +   EL+  V   + + K L++ +L    ++      
Sbjct: 801  LKEQLE--ERSLDHTKEELDAALKKLSELEEKVSMLESENKRLQD-ELIRTSDVDSENKR 857

Query: 1113 IISSTIEPMSDDANNVDXXXXXXXX---XXXXLKVQEEEEFIQERSVLQ--EQSAKLNTE 1167
            ++ +  E   + A N +               +   E+E  I E  + Q  +++     E
Sbjct: 858  LVEAIEEKQKEIAKNEEEAANVTTKLKCTENYISSLEDESQILESKLAQVDQENESAKKE 917

Query: 1168 LQECYTKIIQLETLNTELTGHDVVN--QEQINQLKSKLEQLNTENDNLLSTVAELRSSIS 1225
            ++E   ++ + E    E  G ++ +  Q ++++LK + E+L +E D LL    ++  +  
Sbjct: 918  IEELRQQL-ESERRQKEADGKELSSTYQTELDKLKGENERLKSELDKLLVEKRDVEVNTR 976

Query: 1226 SAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQ---EE 1282
            ++ D +     E   Q L Q    F++ E+ L+  +S  +   +   ++V++ +Q    +
Sbjct: 977  ASSDAQVSLTEEERSQLLDQLSEKFKEIEN-LKATISKDKDSAQMARETVENLSQLISSK 1035

Query: 1283 TNKIVTMEQVTSLQNKLQDK------EEHLRNLQEKYADVINQIEILRSEIEDEKVAFXX 1336
             N+++ +     +    +D+      E+H  +LQ  +A++    +++  +  + + A   
Sbjct: 1036 DNELIKLNATVDMFRNERDEVVKLVQEKHNESLQY-HAEIQRLTQLISDQTANLQKAIAE 1094

Query: 1337 XXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVN 1396
                           L T+N+   Q+ +Q + NI E N   ++               + 
Sbjct: 1095 KDATLASLQEKESQLLWTQNEL--QVVKQRLQNIEESNNHGERCGIAEHTLLSKHVSTLE 1152

Query: 1397 DA----EAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLT 1452
            +     EA +L+    +     ++ +   + TI L     E + +R  LVE E    +  
Sbjct: 1153 EKSKAMEAAILQDQSNIRYLQEQLTEAQSKETIALK----EVDRLRNHLVEMEANYTEEA 1208

Query: 1453 YEKESELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKAL 1512
             + E     L+ ++         MQ E      KL     +  + SV  N+QV  L + L
Sbjct: 1209 LQSEEIQRTLQARL---------MQAEE-----KLKNSSTMYTSASVRANQQVETLQQQL 1254

Query: 1513 EEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASD 1563
               V + +++Q  + + E ++++ +  +TNLQ ++       +K +  A++
Sbjct: 1255 ALIVQQRDDLQNKISSAEDKVLSYSASLTNLQLVLEQFQRDKEKDIQAATE 1305



 Score =  105 bits (251), Expect = 1e-20
 Identities = 160/842 (19%), Positives = 356/842 (42%), Gaps = 60/842 (7%)

Query: 310  IEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPL 369
            +E +  + +     L + IEL+E L   +    +EL+  L    + +K + +        
Sbjct: 571  LESELRVSLERCKGLDENIELIEELKLDLENARRELKIAL----SNNKRLENSLTILQET 626

Query: 370  ISRKSGRNTASKMKSPWSQLSSETLNQDTD-KKINKNEIAKLEMVIQSLNKDLVDKEYVI 428
             +     N     +    +   + L+  +D KK + + +A+L   ++   ++  D EY I
Sbjct: 627  KNEVDADNEVLSREKEQLEADLKLLSSGSDLKKSDGDALAELREQLKKSKEEKDDLEYDI 686

Query: 429  SEKDTXXXXXXXXXXGKDTLIAQLQLEHQQ-HMEGPSLIHVGTNTEDVN----EIAKVQE 483
                                I +LQL++++   E   L+   + T+  N    ++   + 
Sbjct: 687  RNMRNELDQSLEQLEANRAEIEKLQLDNERLAKENGKLLDQFSETQKENLDKVDLLNTEM 746

Query: 484  QLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKT 543
             L Q+  D  KD  ++  +  L   EE+I  L +E +  N    K+K N +++  ++++ 
Sbjct: 747  TLLQQELDGNKD-ELEKTMRYLSDMEEKILTLKNENERLNVEASKIKEN-EIEFLKLKEQ 804

Query: 544  IDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHL-----VDYDSGRMIES-- 596
            ++  S +  + +E+    ++L  L +KV+ LE E   LQ  L     VD ++ R++E+  
Sbjct: 805  LEERS-LDHTKEELDAALKKLSELEEKVSMLESENKRLQDELIRTSDVDSENKRLVEAIE 863

Query: 597  DVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVC 656
            +  K++ + E  A      +   E+    L  E  IL+ K  +V D+  + ++ + +++ 
Sbjct: 864  EKQKEIAKNEEEAANVTTKLKCTENYISSLEDESQILESKLAQV-DQENESAKKEIEELR 922

Query: 657  SEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQE 716
             +++S   +++ D    S       ++ LK + E+L   +  L  +K D+    +     
Sbjct: 923  QQLESERRQKEADGKELS-STYQTELDKLKGENERLKSELDKLLVEKRDVEVNTRASSDA 981

Query: 717  NMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKS 776
             + LT++      +++SE   K    E  K       D+    R+  +EN+   +S   +
Sbjct: 982  QVSLTEEERSQLLDQLSE---KFKEIENLKATISKDKDSAQMARET-VENLSQLISSKDN 1037

Query: 777  RICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRV 836
             + +L  ++ +  + R       D++   +QEK     +Y  +   L     ++ D    
Sbjct: 1038 ELIKLNATVDMFRNER-------DEVVKLVQEKHNESLQYHAEIQRLTQ---LISDQTAN 1087

Query: 837  VEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKY 896
            ++K + E +     LQ+K   LL     LQ+    +Q      +E++N  +  E      
Sbjct: 1088 LQKAIAEKDATLASLQEKESQLLWTQNELQVVKQRLQN-----IEESN--NHGERCGIAE 1140

Query: 897  QTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEY 956
             T L    S L+  +   +  I+Q +  I  L+     Q+  A   + +  ++ ++   +
Sbjct: 1141 HTLLSKHVSTLEEKSKAMEAAILQDQSNIRYLQ----EQLTEAQSKETIALKEVDRLRNH 1196

Query: 957  VTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNA 1016
            + ++EA   E     E +   + +   M  E   K+     T +     Q +  + +  A
Sbjct: 1197 LVEMEANYTEEALQSEEIQRTL-QARLMQAEEKLKNSSTMYTSASVRANQQVETLQQQLA 1255

Query: 1017 LLKQKDEEIIALNQKINNAQ---VSYMSMVSDYESKLAQF-TTKLENMEEEMQRVSKQLL 1072
            L+ Q+ ++   L  KI++A+   +SY + +++ +  L QF   K ++++   +++  +L 
Sbjct: 1256 LIVQQRDD---LQNKISSAEDKVLSYSASLTNLQLVLEQFQRDKEKDIQAATEKLRVELQ 1312

Query: 1073 DSKQHNEELQILVREQDDQIKELKE-----TKLTFEMNIPKTEGMIISSTIEPMSDDANN 1127
             S +  +EL   +    +Q+ E KE     ++LT ++        +++  +  +++  N 
Sbjct: 1313 QSYKKQDELVSEITSLKEQLAEAKECLRAASRLTEQLEKKSERIELLNQEVNRLTELVNT 1372

Query: 1128 VD 1129
             D
Sbjct: 1373 AD 1374



 Score = 98.3 bits (234), Expect = 2e-18
 Identities = 166/790 (21%), Positives = 349/790 (44%), Gaps = 66/790 (8%)

Query: 298  QSIEPSCEEKTEIEE-KGSLEIA--NMTELTKKIELLEHLNCQIRQTNKELENKLATMGT 354
            ++IE   E K ++E  +  L+IA  N   L   + +L+    ++   N+ L  +   +  
Sbjct: 587  ENIELIEELKLDLENARRELKIALSNNKRLENSLTILQETKNEVDADNEVLSREKEQLEA 646

Query: 355  ESKAVSSPSK-KGSPLISRKSGRNTASKMKSPWSQLSSETLNQ--DTDKKI-----NKNE 406
            + K +SS S  K S   +    R    K K     L  +  N   + D+ +     N+ E
Sbjct: 647  DLKLLSSGSDLKKSDGDALAELREQLKKSKEEKDDLEYDIRNMRNELDQSLEQLEANRAE 706

Query: 407  IAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLI 466
            I KL++  + L K+        SE              + TL+ Q +L+  +     ++ 
Sbjct: 707  IEKLQLDNERLAKENGKLLDQFSETQKENLDKVDLLNTEMTLLQQ-ELDGNKDELEKTMR 765

Query: 467  HVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNM 526
            ++    E +  +    E+L  E + +IK+  ++ L  K +  E  +    +E+DAA K +
Sbjct: 766  YLSDMEEKILTLKNENERLNVEAS-KIKENEIEFLKLKEQLEERSLDHTKEELDAALKKL 824

Query: 527  IKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHL- 585
             +++    +   + ++  D   + SD + E  RL E +    +++A+ EEE  N+   L 
Sbjct: 825  SELEEKVSMLESENKRLQDELIRTSDVDSENKRLVEAIEEKQKEIAKNEEEAANVTTKLK 884

Query: 586  --VDYDSGRMIESDVYK-KMIEMENLAETRLKAI----SLLESQKFDLVQELHILQQKYD 638
               +Y S    ES + + K+ +++   E+  K I      LES++     +   L   Y 
Sbjct: 885  CTENYISSLEDESQILESKLAQVDQENESAKKEIEELRQQLESERRQKEADGKELSSTYQ 944

Query: 639  EVEDKLADISQLQSDQVCSEIKSVHLEE---QIDALSASKKELALVIENLKLDKEQLYGT 695
               DKL      +++++ SE+  + +E+   +++  ++S  +++L  E      +QL   
Sbjct: 945  TELDKLKG----ENERLKSELDKLLVEKRDVEVNTRASSDAQVSLTEEERSQLLDQLSEK 1000

Query: 696  IKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELL---AKINHEEQSKIQTQFG 752
             K++EN K  I +K ++  Q   +  + L ++ + K +EL+   A ++     + +    
Sbjct: 1001 FKEIENLKATI-SKDKDSAQMARETVENLSQLISSKDNELIKLNATVDMFRNERDEVVKL 1059

Query: 753  IDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQL---GSYLQ-- 807
            +  K  E   Y   I+        +   L+++IA  +    SL+ K  QL    + LQ  
Sbjct: 1060 VQEKHNESLQYHAEIQRLTQLISDQTANLQKAIAEKDATLASLQEKESQLLWTQNELQVV 1119

Query: 808  -------EKQKAYSEYT-IQEDELVNR-LAVLMDHDRVVEKQLLEIEHENKELQKKNQIL 858
                   E+   + E   I E  L+++ ++ L +  + +E  +L+ +   + LQ++   L
Sbjct: 1120 KQRLQNIEESNNHGERCGIAEHTLLSKHVSTLEEKSKAMEAAILQDQSNIRYLQEQ---L 1176

Query: 859  LEENQNLQISLSDMQQHYNALVE-KANRTDLA-ESESTK--YQTQLRDLESNLKRITHEH 914
             E      I+L ++ +  N LVE +AN T+ A +SE  +   Q +L   E  LK  +  +
Sbjct: 1177 TEAQSKETIALKEVDRLRNHLVEMEANYTEEALQSEEIQRTLQARLMQAEEKLKNSSTMY 1236

Query: 915  QTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEY---VTQLEAQLQEYKNN- 970
             +  V+  +++E L+ +    ++     +  ++   +K + Y   +T L+  L++++ + 
Sbjct: 1237 TSASVRANQQVETLQQQLALIVQQRDDLQNKISSAEDKVLSYSASLTNLQLVLEQFQRDK 1296

Query: 971  -------IENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDE 1023
                    E L + +++  K   EL+ +    ++  +    ++ +   ++L   L++K E
Sbjct: 1297 EKDIQAATEKLRVELQQSYKKQDELVSEITSLKEQLAE--AKECLRAASRLTEQLEKKSE 1354

Query: 1024 EIIALNQKIN 1033
             I  LNQ++N
Sbjct: 1355 RIELLNQEVN 1364



 Score = 79.0 bits (186), Expect = 1e-12
 Identities = 158/808 (19%), Positives = 338/808 (41%), Gaps = 95/808 (11%)

Query: 250  ISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLA--KQSIEPSCEEK 307
            ++ L+E    ++A    +S E  +L  +L+               LA  ++ ++ S EEK
Sbjct: 620  LTILQETKNEVDADNEVLSREKEQLEADLKLLSSGSDLKKSDGDALAELREQLKKSKEEK 679

Query: 308  TEIEEKGSLEIANM-TELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKG 366
             ++E     +I NM  EL + +E LE    +I +   +L+N+              +K+ 
Sbjct: 680  DDLE----YDIRNMRNELDQSLEQLEANRAEIEKL--QLDNERL------------AKEN 721

Query: 367  SPLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLV---- 422
              L+ + S     +  K          L Q+ D   NK+E+ K    +  + + ++    
Sbjct: 722  GKLLDQFSETQKENLDKVDLLNTEMTLLQQELDG--NKDELEKTMRYLSDMEEKILTLKN 779

Query: 423  DKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQ 482
            + E +  E              K+ L  +  L+H +     +L  +    E V+ +    
Sbjct: 780  ENERLNVEASKIKENEIEFLKLKEQL-EERSLDHTKEELDAALKKLSELEEKVSMLESEN 838

Query: 483  EQLKQEL--NDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQM 540
            ++L+ EL    ++   N K L+E ++  +++I + N+E  A     +K   N+   L+  
Sbjct: 839  KRLQDELIRTSDVDSEN-KRLVEAIEEKQKEIAK-NEEEAANVTTKLKCTENYISSLEDE 896

Query: 541  QKTIDN-FSKVSDSN----KEIVRLTEELH-HLSQKVAELEEEKGNLQLHLVDYDS-GRM 593
             + +++  ++V   N    KEI  L ++L     QK A+ +E     Q  L         
Sbjct: 897  SQILESKLAQVDQENESAKKEIEELRQQLESERRQKEADGKELSSTYQTELDKLKGENER 956

Query: 594  IESDVYKKMIEMENL-AETRLKA---ISLLESQKFDLVQELHILQQKYDEVEDKLADISQ 649
            ++S++ K ++E  ++   TR  +   +SL E ++  L+ +L    +K+ E+E+  A IS+
Sbjct: 957  LKSELDKLLVEKRDVEVNTRASSDAQVSLTEEERSQLLDQL---SEKFKEIENLKATISK 1013

Query: 650  LQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNK 709
             +     +     +L + I +      +L   ++  + +++++   +++  N+      +
Sbjct: 1014 DKDSAQMARETVENLSQLISSKDNELIKLNATVDMFRNERDEVVKLVQEKHNESLQYHAE 1073

Query: 710  LQNYIQENMDLTDKLEKMSAEKISELLAKINHEE------QSKIQT------------QF 751
            +Q   Q   D T  L+K  AEK    LA +  +E      Q+++Q               
Sbjct: 1074 IQRLTQLISDQTANLQKAIAEK-DATLASLQEKESQLLWTQNELQVVKQRLQNIEESNNH 1132

Query: 752  GIDAKIQERDLYIENI----------ESELSKYKSRICRLEESIAVMEDRRYSLERKADQ 801
            G    I E  L  +++          E+ + + +S I  L+E +   + +     ++ D+
Sbjct: 1133 GERCGIAEHTLLSKHVSTLEEKSKAMEAAILQDQSNIRYLQEQLTEAQSKETIALKEVDR 1192

Query: 802  LGSYLQEKQKAYSEYTIQEDELVNRL-AVLMDHDRVVEKQL-------LEIEHENKELQK 853
            L ++L E +  Y+E  +Q +E+   L A LM  +  ++          +    + + LQ+
Sbjct: 1193 LRNHLVEMEANYTEEALQSEEIQRTLQARLMQAEEKLKNSSTMYTSASVRANQQVETLQQ 1252

Query: 854  KNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHE 913
            +  +++++  +LQ  +S  +     L   A+ T+L   +    Q Q RD E +++  T +
Sbjct: 1253 QLALIVQQRDDLQNKISSAED--KVLSYSASLTNL---QLVLEQFQ-RDKEKDIQAATEK 1306

Query: 914  HQTLIVQKKKEIEDLEIEFNT------QIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEY 967
             +  + Q  K+ ++L  E  +      + +  +R    L E+ EK  E +  L  ++   
Sbjct: 1307 LRVELQQSYKKQDELVSEITSLKEQLAEAKECLRAASRLTEQLEKKSERIELLNQEVNRL 1366

Query: 968  KNNIENLNMNVEELNKMNLELIDKHVQK 995
               +   +  +EE  K     +D+ + K
Sbjct: 1367 TELVNTADQRIEEAKKSGEGKVDRSLVK 1394



 Score = 70.5 bits (165), Expect = 4e-10
 Identities = 144/679 (21%), Positives = 300/679 (44%), Gaps = 77/679 (11%)

Query: 233  KDEKQRLLKDIESKDVRISSLEEANKLL--EAARF-EISLEHSKLAQELEQXXXXXXXXX 289
            KDE ++ ++ +   + +I +L+  N+ L  EA++  E  +E  KL ++LE+         
Sbjct: 757  KDELEKTMRYLSDMEEKILTLKNENERLNVEASKIKENEIEFLKLKEQLEERSLDH---- 812

Query: 290  XXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENK- 348
                   K+ ++ + ++ +E+EEK      +M E   K  L + L   IR ++ + ENK 
Sbjct: 813  ------TKEELDAALKKLSELEEK-----VSMLESENK-RLQDEL---IRTSDVDSENKR 857

Query: 349  -LATMGTESKAVSSPSKKGSPLISR-KSGRNTASKMKSPWSQLSSETLNQDTDKKINKNE 406
             +  +  + K ++   ++ + + ++ K   N  S ++     L S+    D + +  K E
Sbjct: 858  LVEAIEEKQKEIAKNEEEAANVTTKLKCTENYISSLEDESQILESKLAQVDQENESAKKE 917

Query: 407  IAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLI 466
            I +L    Q L  +   KE    E  +          G++    +L+ E  + +     +
Sbjct: 918  IEELR---QQLESERRQKEADGKELSSTYQTELDKLKGEN---ERLKSELDKLLVEKRDV 971

Query: 467  HVGTNTEDVNEIAKVQE---QLKQELNDEIKDV-NVKDLIEKLKSAEEQITQLNDEIDAA 522
             V T      +++  +E   QL  +L+++ K++ N+K  I K K + +   +  + +   
Sbjct: 972  EVNTRASSDAQVSLTEEERSQLLDQLSEKFKEIENLKATISKDKDSAQMARETVENL--- 1028

Query: 523  NKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLS-------QKVAEL- 574
               +I  K N  +KL     T+D F    D   E+V+L +E H+ S       Q++ +L 
Sbjct: 1029 -SQLISSKDNELIKL---NATVDMFRNERD---EVVKLVQEKHNESLQYHAEIQRLTQLI 1081

Query: 575  EEEKGNLQLHLVDYDSGRMIESDVYKKMIEMEN-LAETRLKAISLLESQKFDL---VQEL 630
             ++  NLQ  + + D+      +   +++  +N L   + +  ++ ES        + E 
Sbjct: 1082 SDQTANLQKAIAEKDATLASLQEKESQLLWTQNELQVVKQRLQNIEESNNHGERCGIAEH 1141

Query: 631  HILQQKYDEVEDK-LADISQLQSDQVCSEIKSVHLEEQIDALSASKKELAL-VIENLKLD 688
             +L +    +E+K  A  + +  DQ  S I+  +L+EQ+   + SK+ +AL  ++ L+  
Sbjct: 1142 TLLSKHVSTLEEKSKAMEAAILQDQ--SNIR--YLQEQLTE-AQSKETIALKEVDRLRNH 1196

Query: 689  KEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQ 748
              ++     +     E+I   LQ  +   M   +KL K S+   +    + N + ++ +Q
Sbjct: 1197 LVEMEANYTEEALQSEEIQRTLQARL---MQAEEKL-KNSSTMYTSASVRANQQVET-LQ 1251

Query: 749  TQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQ- 807
             Q  +   +Q+RD     I S   K  S    L     V+E  +   E+        L+ 
Sbjct: 1252 QQLAL--IVQQRDDLQNKISSAEDKVLSYSASLTNLQLVLEQFQRDKEKDIQAATEKLRV 1309

Query: 808  EKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQI 867
            E Q++Y     ++DELV+ +  L +     ++ L       ++L+KK++ +   NQ +  
Sbjct: 1310 ELQQSYK----KQDELVSEITSLKEQLAEAKECLRAASRLTEQLEKKSERIELLNQEVN- 1364

Query: 868  SLSDMQQHYNALVEKANRT 886
             L+++    +  +E+A ++
Sbjct: 1365 RLTELVNTADQRIEEAKKS 1383



 Score = 65.3 bits (152), Expect = 1e-08
 Identities = 175/883 (19%), Positives = 368/883 (41%), Gaps = 97/883 (10%)

Query: 742  EEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQ 801
            E QSK+     +  ++ +  + I ++ESEL++ ++       S  V +D     E  A Q
Sbjct: 89   ENQSKL-----LQDQLDQATVRIRDLESELNRVQTL-----NSSNVKDDANIK-EEGASQ 137

Query: 802  LGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEE 861
                L+ KQ   +   IQ  E      V+ +  R+ + +L  +    K + K      E+
Sbjct: 138  KAELLRAKQDVMNRI-IQMGEKSRE--VVRNAKRLQQDELTLVGDFRKAISKLASP--EQ 192

Query: 862  NQNLQISLSDMQQHYNALVEKANRTDLA--ESESTKYQTQLRD-LESNLKRITHEHQTLI 918
               ++ +L  ++     L   A +TD    ++E      + RD  E+ L+R   + +   
Sbjct: 193  YDLIRSALMALENESEQLQGSAEKTDSVGYDAEGKSRNEKGRDESEAKLRRRVEDLEAEN 252

Query: 919  VQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNV 978
                + IE+L+ +    IE  +  K+ L +K+        QL  +  +    IENL    
Sbjct: 253  QSLSQSIEELDKQNAESIERVLSLKEELQKKHHSLQGAYEQLYVEYNQALGKIENLQQQQ 312

Query: 979  E--------ELNKM-NLELIDKHVQK-QQTQSPDYTEQYINEINKLNALLKQKDEEIIAL 1028
            +        EL+K  N   +D  VQ   Q +    TE    + +K   +   K+++ + +
Sbjct: 313  QQQQQQQKPELSKAPNKSSLDTAVQTLAQLKLDKETEIRPAKEDKQTEISTSKEDKEVEV 372

Query: 1029 NQKINNAQ--VSYMSMVSDYESKLAQFTTKLENMEEEM-QRVSKQLLDSKQHNEELQILV 1085
            + K  + Q   S +  V+D   K A      E++ + +   V++Q ++ K   E L+  +
Sbjct: 373  DLKPEDQQDLASELKKVNDI-LKNAPLEPSNEHLNDSVFVAVARQFVELKWKKETLERKL 431

Query: 1086 REQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQ 1145
             EQ  Q+KE +E + + +++    +  I S  +E +    +N+             L+  
Sbjct: 432  TEQSRQLKETQELRDSLQIDCEDMQTNIESLVME-VQHLKSNLPSIPEASEERVASLET- 489

Query: 1146 EEEEFIQERSVLQEQSAKLNTELQECYTKI--------IQLETLNTELTGHDVVNQEQIN 1197
            E E    E   L++  A +++EL+     I        ++L T    L      N+ + +
Sbjct: 490  ETESLQAEILALRKSKADMSSELKAIKAAIREDGGGGGVELATRIESLLAEQ--NKSKSS 547

Query: 1198 QLKSKLEQLN-TENDNLLSTVAELRSSISSAVDQ-RGF-EIAELWKQHLAQREADFQKTE 1254
            +  ++L Q    EN  L   +  L S +  ++++ +G  E  EL    + + + D +   
Sbjct: 548  KDPAELLQATLDENTALRRRIDVLESELRVSLERCKGLDENIEL----IEELKLDLENAR 603

Query: 1255 HELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHL----RNLQ 1310
             EL++ LS       + L++  +  QE  N++    +V S + +  + +  L     +L+
Sbjct: 604  RELKIALS-----NNKRLENSLTILQETKNEVDADNEVLSREKEQLEADLKLLSSGSDLK 658

Query: 1311 EKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNI 1370
            +   D + ++     + ++EK                   DL  + ++ +   +QS+  +
Sbjct: 659  KSDGDALAELREQLKKSKEEK------------------DDLEYDIRNMRNELDQSLEQL 700

Query: 1371 NEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQR 1430
                A+++K               ++       E   +++L ++E+     E    L   
Sbjct: 701  EANRAEIEKLQLDNERLAKENGKLLDQFSETQKENLDKVDLLNTEMTLLQQE----LDGN 756

Query: 1431 NDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERV-KLIE 1489
             DE E   + L + E++I  L  E E  L +   K+ EN   +  ++++ E   +    E
Sbjct: 757  KDELEKTMRYLSDMEEKILTLKNENE-RLNVEASKIKENEIEFLKLKEQLEERSLDHTKE 815

Query: 1490 ELNVKITESVSLNKQVAEL---NKALEEEVAKTNEMQT-------ALENQEIEIVTLNDE 1539
            EL+  + +   L ++V+ L   NK L++E+ +T+++ +       A+E ++ EI    +E
Sbjct: 816  ELDAALKKLSELEEKVSMLESENKRLQDELIRTSDVDSENKRLVEAIEEKQKEIAKNEEE 875

Query: 1540 ITNLQNMVRASSSKIQ--KHVSFASDTKQGRDEQLDNTMNKEL 1580
              N+   ++ + + I   +  S   ++K  + +Q + +  KE+
Sbjct: 876  AANVTTKLKCTENYISSLEDESQILESKLAQVDQENESAKKEI 918



 Score = 54.0 bits (124), Expect = 3e-05
 Identities = 129/676 (19%), Positives = 282/676 (41%), Gaps = 67/676 (9%)

Query: 141  LGDVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXX 200
            L D+     T+K ++  L+V   K+K  E   L L+E++ E+  +   K +         
Sbjct: 767  LSDMEEKILTLKNENERLNVEASKIKENEIEFLKLKEQLEER-SLDHTKEELDAALKKLS 825

Query: 201  XXXXXXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLL 260
                       E+      ++Q+  I   ++   E +RL++ IE K   I+  EE    +
Sbjct: 826  ELEEKVSMLESEN-----KRLQDELI-RTSDVDSENKRLVEAIEEKQKEIAKNEEEAANV 879

Query: 261  EAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIAN 320
               + + +  +    ++  Q               AK+ IE   E + ++E +   + A+
Sbjct: 880  -TTKLKCTENYISSLEDESQILESKLAQVDQENESAKKEIE---ELRQQLESERRQKEAD 935

Query: 321  MTELTKKIEL-LEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTA 379
              EL+   +  L+ L  +  +   EL+ KL     + +  +  S      ++ +      
Sbjct: 936  GKELSSTYQTELDKLKGENERLKSELD-KLLVEKRDVEVNTRASSDAQVSLTEEERSQLL 994

Query: 380  SKMKSPWSQLSS--ETLNQDTDK-KINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXX 436
             ++   + ++ +   T+++D D  ++ +  +  L  +I S + +L+     +        
Sbjct: 995  DQLSEKFKEIENLKATISKDKDSAQMARETVENLSQLISSKDNELIKLNATVD------- 1047

Query: 437  XXXXXXXGKDTLIAQLQLEH----QQHMEGPSLIH-VGTNTEDVNE-IAKVQEQLKQELN 490
                    +D ++  +Q +H    Q H E   L   +   T ++ + IA+    L     
Sbjct: 1048 ---MFRNERDEVVKLVQEKHNESLQYHAEIQRLTQLISDQTANLQKAIAEKDATLASLQE 1104

Query: 491  DEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKV 550
             E + +  ++ ++ +K   + I + N+  +        + S H   L++  K ++  + +
Sbjct: 1105 KESQLLWTQNELQVVKQRLQNIEESNNHGERCGIAEHTLLSKHVSTLEEKSKAME--AAI 1162

Query: 551  SDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSG---RMIESDVYKKMIEMEN 607
                  I  L E+L     K     +E   L+ HLV+ ++      ++S+  ++ ++   
Sbjct: 1163 LQDQSNIRYLQEQLTEAQSKETIALKEVDRLRNHLVEMEANYTEEALQSEEIQRTLQARL 1222

Query: 608  L-AETRLK-AISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLE 665
            + AE +LK + ++  S      Q++  LQQ       +LA I Q Q D + ++I S   E
Sbjct: 1223 MQAEEKLKNSSTMYTSASVRANQQVETLQQ-------QLALIVQ-QRDDLQNKISSA--E 1272

Query: 666  EQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLE 725
            +++ + SAS   L LV+E  + DKE      KD++   E +  +LQ   ++  +L  ++ 
Sbjct: 1273 DKVLSYSASLTNLQLVLEQFQRDKE------KDIQAATEKLRVELQQSYKKQDELVSEIT 1326

Query: 726  KMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESI 785
             +  E+++E  AK      S++  Q      ++++   IE +  E+++    +   ++ I
Sbjct: 1327 SLK-EQLAE--AKECLRAASRLTEQ------LEKKSERIELLNQEVNRLTELVNTADQRI 1377

Query: 786  AVMEDRRYSLERKADQ 801
               E+ + S E K D+
Sbjct: 1378 ---EEAKKSGEGKVDR 1390


>UniRef50_Q4S7F6 Cluster: Chromosome 13 SCAF14715, whole genome
            shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 13
            SCAF14715, whole genome shotgun sequence - Tetraodon
            nigroviridis (Green puffer)
          Length = 1396

 Score =  122 bits (294), Expect = 8e-26
 Identities = 249/1268 (19%), Positives = 530/1268 (41%), Gaps = 134/1268 (10%)

Query: 303  SCEEKTEIEE-KGSL-EIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVS 360
            S E K E+++ +G L ++     L +K+   E     I+Q     E K A + TE   + 
Sbjct: 63   SGELKKELDKVQGHLKQVIPFRSLERKLNEAETEKFNIKQMKDLFEQKAAQLATEIVDLK 122

Query: 361  SPSKKGSPLISRKSGR-----NTASKMKSPWSQLSSETLNQD--TDKKINKNEIAKLEMV 413
            S   +   L      +         + K    +L +E L +    D ++ + E+ +++ +
Sbjct: 123  SRYDEEKSLRDAADHKLANLNEQLQREKQEKERLLTELLQRPGVEDVEVLQKELVQVQTL 182

Query: 414  IQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNT- 472
            + S+ ++   +E                    +  IAQL+ E ++   GP  + V T   
Sbjct: 183  MDSMTRE---REEESERLKNHYEQLQANYTNSEMTIAQLKAELEK---GPQEVAVYTKEI 236

Query: 473  ----EDVNEIAKVQEQLKQELNDEIKD-VNVKDLIEKLKSAEEQITQLNDEIDAANKNMI 527
                  +N + +  + L ++L  + KD + +++++ K K ++++      E D   + + 
Sbjct: 237  HELRSSLNSLQQQSQSLSEKLEQKEKDYLQLEEMLAKEKGSKKKAQDGLKERDQEVQELQ 296

Query: 528  KVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNL-QLHLV 586
               +  +  L++ Q      +++ +  +E+ +L  E+  L  K AEL+ E+  L QL   
Sbjct: 297  ARLAGAETSLQKAQ------AELQERTEEVSKLRSEMGELEVKHAELKVERKQLEQLREE 350

Query: 587  DYDSGRMIESDV---YKKMIEMENL---AETRLKAISLLESQKF-DLVQELHILQQKYDE 639
                G   ++++   + K++E E      E RLK    L  +K  D  Q+   LQ K   
Sbjct: 351  KESHGAQQQTEIGQLHAKLLETERQLGEVEGRLKEQRQLSGEKLKDREQQAADLQLKLSR 410

Query: 640  VEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDL 699
             E++L +          S  K+  L+ Q++      +EL ++ +N         G +++ 
Sbjct: 411  TEEQLKE----------SATKNTDLQHQLEKAKQQHQELQVLQQNTN-------GKLREA 453

Query: 700  ENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQE 759
            +ND E ++ ++ +  Q+  +L   L+K S + +S+L A+   +  +KIQ   G  A + +
Sbjct: 454  QNDLEQVLRQIGDKDQKIQNLEALLQK-SKDIVSQLEAE-RDDLCAKIQAGEGETAVLNQ 511

Query: 760  RDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEK----QKAYSE 815
                 + ++ ++++   ++    ES    +D  +   ++   L    Q++    +   +E
Sbjct: 512  LKDKNQALQGQVTQLTDKLKNQSESNKQAQDNLHKQVQEQKTLLRSAQDRAHTMETTVTE 571

Query: 816  YTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQH 875
             T Q  +   +++ L    +   + LL  E   K  QK N  +    +  Q +L D QQ 
Sbjct: 572  LTAQLTDSKEKVSQLDAQLKAKTEMLLSAEAA-KAAQKAN--MENSLETAQHALQDKQQE 628

Query: 876  YNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQ 935
             N + +K      +  E  +  TQL   E+N+K    E++  ++  ++  E L+   N +
Sbjct: 629  LNKVQKKIEEQTQSLKEKREQCTQL---ETNVK----EYKDKLLASEQRTEQLQ-SLNKR 680

Query: 936  IESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQK 995
            +ES + + +  +E+ ++ ++ + +   ++++    +++ ++  E+  K+   L D  +QK
Sbjct: 681  LESQLGELQTAHEQVQQQVQKLQKESTEMKQKAKELQH-SLETEKAGKLQNLLAD--LQK 737

Query: 996  QQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTT 1055
             Q +     E +  EI  L   L +  +   AL +  N         V D E K  Q  +
Sbjct: 738  AQQEK----EAHKKEIGSLQENLGKTKK---ALKESQN---------VLDAERKSHQ--S 779

Query: 1056 KLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIIS 1115
             +E  ++  Q+  ++LL   + NE L   + E  DQ+++++E + + ++ +   E   + 
Sbjct: 780  AVEERDKSNQKARQELL---KKNEALTKTMNESKDQLEQMREAEKSLKVQLTSVEQQQVK 836

Query: 1116 STIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKI 1175
            +  E +    N ++            L+V E ++   + + LQE   K   E ++   ++
Sbjct: 837  AQ-EALKQKQNQLEKLQAQLQTVEGSLEV-ETKKLKGQIAELQESGVKKAKEEKQLRAQV 894

Query: 1176 IQL-ETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFE 1234
              L E L +E      V Q+ + Q +    +L ++     + V+ L   + +  ++    
Sbjct: 895  AGLSEELASEKRRTTEV-QKALEQSQESQSKLQSDLYGKETEVSALHQDLRACEEKLKLA 953

Query: 1235 IAELW--KQHLAQREADFQKTE---HELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTM 1289
              EL   + H    EA  Q+ +     L  +L   E K +Q   +++ S + +T     +
Sbjct: 954  QEELAGNQTHQTGLEAQIQELQVSRGSLEEELGKLEHKLQQREQTLKDSEKHQTQVKEEL 1013

Query: 1290 EQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSE----IEDEKVAFXXXXXXXXXXX 1345
            ++  S   +L   +  L N   + A  +  ++    +    +++ K+             
Sbjct: 1014 KREKSKAEELNKLKNDLENNSSRLAADLKALKEKSDKELGNLQEAKLLLIQQKLELQTQV 1073

Query: 1346 XXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLEL 1405
                 DL  E + ++  ++ S+    +  AQ+K               +  + +AK  E 
Sbjct: 1074 EAAQGDLEQERKEHQSTKDGSLRRKEQLLAQIKDVQDQLSSEK-----KAREEQAKRGE- 1127

Query: 1406 THQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLK 1465
              + E + S      +E   TL +   E++  ++++ E EK+ +DL      E+A+L   
Sbjct: 1128 --EAEARTSAQVTALNENVATLKR---EWQGSQRRVGELEKQTDDL----RGEIAVLEAT 1178

Query: 1466 MHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTA 1525
            +  N +           ER  L+E       E   L  +V EL + LE+  A   E+   
Sbjct: 1179 VQNNQD-----------ERRALLERCVKGEGEIEKLQAKVVELRRKLEDTTAAMQEL--G 1225

Query: 1526 LENQEIEI 1533
             ENQ ++I
Sbjct: 1226 RENQSLQI 1233



 Score =  118 bits (284), Expect = 1e-24
 Identities = 186/907 (20%), Positives = 373/907 (41%), Gaps = 87/907 (9%)

Query: 715  QENMDLTDKL--EKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELS 772
            QE  DL   L  E+  + ++ + L K+    +  I  +  ++ K+ E +    NI+    
Sbjct: 47   QEVQDLHASLKEERWFSGELKKELDKVQGHLKQVIPFR-SLERKLNEAETEKFNIKQMKD 105

Query: 773  KYKSRICRLEESIAVME---DRRYSLERKAD-QLGSYLQEKQKAYSEYTIQEDELVNRLA 828
             ++ +  +L   I  ++   D   SL   AD +L +  ++ Q+   E      EL+ R  
Sbjct: 106  LFEQKAAQLATEIVDLKSRYDEEKSLRDAADHKLANLNEQLQREKQEKERLLTELLQRPG 165

Query: 829  VLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYN----ALVEKAN 884
            V  +   V++K+L++++     + ++ +   EE++ L+     +Q +Y      + +   
Sbjct: 166  V--EDVEVLQKELVQVQTLMDSMTRERE---EESERLKNHYEQLQANYTNSEMTIAQLKA 220

Query: 885  RTDLAESESTKYQTQLRDLESNLKRITHEHQTL---IVQKKKEIEDLEIEFNTQIESAIR 941
              +    E   Y  ++ +L S+L  +  + Q+L   + QK+K+   LE     +  S  +
Sbjct: 221  ELEKGPQEVAVYTKEIHELRSSLNSLQQQSQSLSEKLEQKEKDYLQLEEMLAKEKGSKKK 280

Query: 942  DKKVLNEKYEKNIEYVTQL----------EAQLQEYKNNIENLNMNVEELNKMNLEL-ID 990
             +  L E+ ++  E   +L          +A+LQE    +  L   + EL   + EL ++
Sbjct: 281  AQDGLKERDQEVQELQARLAGAETSLQKAQAELQERTEEVSKLRSEMGELEVKHAELKVE 340

Query: 991  -KHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESK 1049
             K +++ + +   +  Q   EI +L+A L + + ++  +  ++   +      + D E +
Sbjct: 341  RKQLEQLREEKESHGAQQQTEIGQLHAKLLETERQLGEVEGRLKEQRQLSGEKLKDREQQ 400

Query: 1050 LAQFTTKLENMEEEMQR-------VSKQLLDSKQHNEELQIL-------VREQDDQIKEL 1095
             A    KL   EE+++        +  QL  +KQ ++ELQ+L       +RE  + ++++
Sbjct: 401  AADLQLKLSRTEEQLKESATKNTDLQHQLEKAKQQHQELQVLQQNTNGKLREAQNDLEQV 460

Query: 1096 KETKLTFEMNIPKTEGMI-----ISSTIEPMSDDA--------------NNVDXXXXXXX 1136
                   +  I   E ++     I S +E   DD               N +        
Sbjct: 461  LRQIGDKDQKIQNLEALLQKSKDIVSQLEAERDDLCAKIQAGEGETAVLNQLKDKNQALQ 520

Query: 1137 XXXXXL--KVQEEEEFI-QERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQ 1193
                 L  K++ + E   Q +  L +Q  +  T L+    +   +ET  TELT     ++
Sbjct: 521  GQVTQLTDKLKNQSESNKQAQDNLHKQVQEQKTLLRSAQDRAHTMETTVTELTAQLTDSK 580

Query: 1194 EQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKT 1253
            E+++QL +   QL  + + LLS  AE   +   A  +   E A+     L  ++ +  K 
Sbjct: 581  EKVSQLDA---QLKAKTEMLLS--AEAAKAAQKANMENSLETAQ---HALQDKQQELNKV 632

Query: 1254 EHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTS-LQNKLQDKEEHLRNLQEK 1312
            + ++  Q  + + K EQ    ++++ +E  +K++  EQ T  LQ+  +  E  L  LQ  
Sbjct: 633  QKKIEEQTQSLKEKREQCTQ-LETNVKEYKDKLLASEQRTEQLQSLNKRLESQLGELQTA 691

Query: 1313 YADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINE 1372
            +  V  Q++ L+ E  + K                   +L  + Q  +Q +E     I  
Sbjct: 692  HEQVQQQVQKLQKESTEMKQKAKELQHSLETEKAGKLQNLLADLQKAQQEKEAHKKEIGS 751

Query: 1373 ENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRND 1432
                L K+                  ++ V E     +    E+ +K    T T+ +  D
Sbjct: 752  LQENLGKTKKALKESQNVLDAERKSHQSAVEERDKSNQKARQELLKKNEALTKTMNESKD 811

Query: 1433 EFENVRQ-------QLVEYEK---RIEDLTYEKESELAILRLKMHENANHYETMQKESEI 1482
            + E +R+       QL   E+   + ++   +K+++L  L+ ++       E   K+ + 
Sbjct: 812  QLEQMREAEKSLKVQLTSVEQQQVKAQEALKQKQNQLEKLQAQLQTVEGSLEVETKKLKG 871

Query: 1483 ERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITN 1542
            +  +L E    K  E   L  QVA L++ L  E  +T E+Q ALE  +     L  ++  
Sbjct: 872  QIAELQESGVKKAKEEKQLRAQVAGLSEELASEKRRTTEVQKALEQSQESQSKLQSDLYG 931

Query: 1543 LQNMVRA 1549
             +  V A
Sbjct: 932  KETEVSA 938



 Score =  111 bits (266), Expect = 2e-22
 Identities = 214/1107 (19%), Positives = 452/1107 (40%), Gaps = 104/1107 (9%)

Query: 510  EQITQLNDEIDAANKNMIKVK---SNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHH 566
            E +T L  E+   + ++ + +      K +L ++Q  +          +++     E  +
Sbjct: 40   EDLTMLRQEVQDLHASLKEERWFSGELKKELDKVQGHLKQVIPFRSLERKLNEAETEKFN 99

Query: 567  LSQKVAELEEEKGNLQLHLVD----YDSGRMIESDVYKKMIEM-ENLA-ETRLKAISLLE 620
            + Q     E++   L   +VD    YD  + +      K+  + E L  E + K   L E
Sbjct: 100  IKQMKDLFEQKAAQLATEIVDLKSRYDEEKSLRDAADHKLANLNEQLQREKQEKERLLTE 159

Query: 621  SQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELAL 680
              +   V+++ +LQ++  +V+  +  +++ + ++      S  L+   + L A+     +
Sbjct: 160  LLQRPGVEDVEVLQKELVQVQTLMDSMTREREEE------SERLKNHYEQLQANYTNSEM 213

Query: 681  VIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAE--KISELLAK 738
             I  LK + E+    +     +  ++ + L +  Q++  L++KLE+   +  ++ E+LAK
Sbjct: 214  TIAQLKAELEKGPQEVAVYTKEIHELRSSLNSLQQQSQSLSEKLEQKEKDYLQLEEMLAK 273

Query: 739  INHEEQSKIQTQFGI---DAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSL 795
               E+ SK + Q G+   D ++QE    +   E+ L K ++ +    E ++ +      L
Sbjct: 274  ---EKGSKKKAQDGLKERDQEVQELQARLAGAETSLQKAQAELQERTEEVSKLRSEMGEL 330

Query: 796  ERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKN 855
            E K  +L   ++ KQ    E   +E E  +  A        +  +LLE E +  E++ + 
Sbjct: 331  EVKHAELK--VERKQL---EQLREEKE--SHGAQQQTEIGQLHAKLLETERQLGEVEGR- 382

Query: 856  QILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQ 915
              L E+ Q     L D +Q    L  K +RT+    ES    T   DL+  L++   +HQ
Sbjct: 383  --LKEQRQLSGEKLKDREQQAADLQLKLSRTEEQLKESATKNT---DLQHQLEKAKQQHQ 437

Query: 916  TLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLN 975
             L V ++     L  E    +E  +R    + +K +K    +  LEA LQ+ K+ +  L 
Sbjct: 438  ELQVLQQNTNGKLR-EAQNDLEQVLRQ---IGDKDQK----IQNLEALLQKSKDIVSQLE 489

Query: 976  MNVEEL-NKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINN 1034
               ++L  K+     +  V  Q     D  +    ++ +L   LK + E     N++   
Sbjct: 490  AERDDLCAKIQAGEGETAVLNQLK---DKNQALQGQVTQLTDKLKNQSES----NKQ--- 539

Query: 1035 AQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKE 1094
            AQ +    V + ++ L     +   ME  +  ++ QL DSK+   +L   ++ + + +  
Sbjct: 540  AQDNLHKQVQEQKTLLRSAQDRAHTMETTVTELTAQLTDSKEKVSQLDAQLKAKTEMLLS 599

Query: 1095 LKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQER 1154
             +  K   + N+  +        ++    + N V              K++E+ + ++E+
Sbjct: 600  AEAAKAAQKANMENSLETA-QHALQDKQQELNKVQK------------KIEEQTQSLKEK 646

Query: 1155 SVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLL 1214
               +EQ  +L T ++E   K++  E    +L   +   + Q+ +L++  EQ+  +   L 
Sbjct: 647  ---REQCTQLETNVKEYKDKLLASEQRTEQLQSLNKRLESQLGELQTAHEQVQQQVQKLQ 703

Query: 1215 STVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDS 1274
                E++        Q   E  +  K  L    AD QK + E         S  E L   
Sbjct: 704  KESTEMKQKAKEL--QHSLETEKAGK--LQNLLADLQKAQQEKEAHKKEIGSLQENL--G 757

Query: 1275 VQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAF 1334
                  +E+  ++  E+  S Q+ +++++   ++ Q+   +++ + E L   + + K   
Sbjct: 758  KTKKALKESQNVLDAER-KSHQSAVEERD---KSNQKARQELLKKNEALTKTMNESK--- 810

Query: 1335 XXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXR 1394
                             L+ +  S +Q Q ++   + ++  QL+K               
Sbjct: 811  -----DQLEQMREAEKSLKVQLTSVEQQQVKAQEALKQKQNQLEKLQAQLQTVEGSLEVE 865

Query: 1395 VNDAEAKVLELTHQLELKDSEIYQKT------HEYTITLTQRNDEFENVRQQLVEYEKRI 1448
                + ++ EL      K  E  Q         E   +  +R  E +   +Q  E + ++
Sbjct: 866  TKKLKGQIAELQESGVKKAKEEKQLRAQVAGLSEELASEKRRTTEVQKALEQSQESQSKL 925

Query: 1449 EDLTYEKESELAILRLKMHENANHYETMQKE---SEIERVKLIEELNVKITESVSLNKQV 1505
            +   Y KE+E++ L   +       +  Q+E   ++  +  L  ++        SL +++
Sbjct: 926  QSDLYGKETEVSALHQDLRACEEKLKLAQEELAGNQTHQTGLEAQIQELQVSRGSLEEEL 985

Query: 1506 AELNKALE--EEVAKTNEM-QTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFAS 1562
             +L   L+  E+  K +E  QT ++ +     +  +E+  L+N +  +SS++   +    
Sbjct: 986  GKLEHKLQQREQTLKDSEKHQTQVKEELKREKSKAEELNKLKNDLENNSSRLAADL---K 1042

Query: 1563 DTKQGRDEQLDNTMNKELLDAVPRAEL 1589
              K+  D++L N    +LL    + EL
Sbjct: 1043 ALKEKSDKELGNLQEAKLLLIQQKLEL 1069



 Score = 93.1 bits (221), Expect = 6e-17
 Identities = 203/1107 (18%), Positives = 444/1107 (40%), Gaps = 80/1107 (7%)

Query: 51   QIKFERAQKCLENAALVSKRIKEHRKATAELLGRPFVPGISESLANTLKQKE---ILMEK 107
            Q+K E  +K  +  A+ +K I E R +   L  +      S+SL+  L+QKE   + +E+
Sbjct: 217  QLKAE-LEKGPQEVAVYTKEIHELRSSLNSLQQQ------SQSLSEKLEQKEKDYLQLEE 269

Query: 108  IKQYKELSKRSSTTIVRXXXXXXXXXXXXXXXQLGDVTHLSNTIKEKDNALSVLQVKMKI 167
            +   ++ SK+ +   ++                   +      ++E+   +S L+ +M  
Sbjct: 270  MLAKEKGSKKKAQDGLKERDQEVQELQARLAGAETSLQKAQAELQERTEEVSKLRSEMGE 329

Query: 168  METTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXXXXXXXEDTKQQMTKMQENFIA 227
            +E    +L+ +  + +Q+ E K                          +   +++E    
Sbjct: 330  LEVKHAELKVERKQLEQLREEKESHGAQQQTEIGQLHAKLLETERQLGEVEGRLKEQRQL 389

Query: 228  MEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHS-KLAQELEQXXXXXX 286
               + KD +Q+   D++ K   +S  EE  +L E+A     L+H  + A++  Q      
Sbjct: 390  SGEKLKDREQQAA-DLQLK---LSRTEE--QLKESATKNTDLQHQLEKAKQQHQELQVLQ 443

Query: 287  XXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELE 346
                     A+  +E    +  + ++K    I N+  L +K +    +  Q+     +L 
Sbjct: 444  QNTNGKLREAQNDLEQVLRQIGDKDQK----IQNLEALLQKSK---DIVSQLEAERDDLC 496

Query: 347  NKLATMGTESKAVSSPSKKGSPLISRKSG-----RNTASKMKSPWSQLSSETLNQDTDKK 401
             K+     E+  ++    K   L  + +      +N +   K     L  +   Q T  +
Sbjct: 497  AKIQAGEGETAVLNQLKDKNQALQGQVTQLTDKLKNQSESNKQAQDNLHKQVQEQKTLLR 556

Query: 402  INKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHME 461
              ++    +E  +  L   L D +  +S+ D             +   A  +   +  +E
Sbjct: 557  SAQDRAHTMETTVTELTAQLTDSKEKVSQLDAQLKAKTEMLLSAEAAKAAQKANMENSLE 616

Query: 462  GPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIK-----DVNVKDLIEKLKSAEEQITQLN 516
                  +    +++N++ K  E+  Q L ++ +     + NVK+  +KL ++E++  QL 
Sbjct: 617  TAQHA-LQDKQQELNKVQKKIEEQTQSLKEKREQCTQLETNVKEYKDKLLASEQRTEQLQ 675

Query: 517  DEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRL--TEELHHLSQKVAEL 574
                     + ++++ H+   +Q+QK     +++    KE+     TE+   L   +A+L
Sbjct: 676  SLNKRLESQLGELQTAHEQVQQQVQKLQKESTEMKQKAKELQHSLETEKAGKLQNLLADL 735

Query: 575  EEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQ 634
            ++ +   + H  +  S +       K + E +N+ +   K+      ++    Q+     
Sbjct: 736  QKAQQEKEAHKKEIGSLQENLGKTKKALKESQNVLDAERKSHQSAVEERDKSNQKARQEL 795

Query: 635  QKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYG 694
             K +E   K  + S+ Q +Q+    KS  L+ Q+ ++   + +    ++  +   E+L  
Sbjct: 796  LKKNEALTKTMNESKDQLEQMREAEKS--LKVQLTSVEQQQVKAQEALKQKQNQLEKLQA 853

Query: 695  TIKDLENDKEDIMNKLQNYI---QENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQF 751
             ++ +E   E    KL+  I   QE+     K EK    +++ L  ++  E++   + Q 
Sbjct: 854  QLQTVEGSLEVETKKLKGQIAELQESGVKKAKEEKQLRAQVAGLSEELASEKRRTTEVQK 913

Query: 752  GID------AKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSY 805
             ++      +K+Q  DLY +  E+E+S     +   EE + + ++     +     L + 
Sbjct: 914  ALEQSQESQSKLQS-DLYGK--ETEVSALHQDLRACEEKLKLAQEELAGNQTHQTGLEAQ 970

Query: 806  LQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNL 865
            +QE Q +      +  +L ++L       +  EK   +++ E K  + K + L +   +L
Sbjct: 971  IQELQVSRGSLEEELGKLEHKLQQREQTLKDSEKHQTQVKEELKREKSKAEELNKLKNDL 1030

Query: 866  QISLSDMQQHYNALVEKANRT--DLAES------ESTKYQTQLRDLESNLKRITHEHQTL 917
            + + S +     AL EK+++   +L E+      +  + QTQ+   + +L++   EHQ+ 
Sbjct: 1031 ENNSSRLAADLKALKEKSDKELGNLQEAKLLLIQQKLELQTQVEAAQGDLEQERKEHQST 1090

Query: 918  IVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMN 977
                 +  E L  +     +    +KK   E+ ++  E   +  AQ+     N+  L   
Sbjct: 1091 KDGSLRRKEQLLAQIKDVQDQLSSEKKAREEQAKRGEEAEARTSAQVTALNENVATLKRE 1150

Query: 978  VEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQV 1037
             +   +   EL     +KQ       T+    EI  L A ++   +E  AL ++     V
Sbjct: 1151 WQGSQRRVGEL-----EKQ-------TDDLRGEIAVLEATVQNNQDERRALLERC----V 1194

Query: 1038 SYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVRE--QDDQIKEL 1095
                 +   ++K+ +   KLE+    MQ + ++  +     ++ Q L R+  +D +++  
Sbjct: 1195 KGEGEIEKLQAKVVELRRKLEDTTAAMQELGRE--NQSLQIKQSQSLTRKWAEDHEVQSC 1252

Query: 1096 KETKLTFEMNIPKTEGMIISSTIEPMS 1122
                  F + + K  G    S + P+S
Sbjct: 1253 MGCGKGFSVTVRKVGG-APKSPLSPIS 1278


>UniRef50_Q115P0 Cluster: Chromosome segregation ATPase-like protein;
            n=1; Trichodesmium erythraeum IMS101|Rep: Chromosome
            segregation ATPase-like protein - Trichodesmium
            erythraeum (strain IMS101)
          Length = 1209

 Score =  122 bits (294), Expect = 8e-26
 Identities = 177/827 (21%), Positives = 358/827 (43%), Gaps = 65/827 (7%)

Query: 327  KIELLEHLNCQIRQTNKELENKLATM-GTESKAVSSPSKKGSPLISRKSGRNTASKMKSP 385
            ++EL E +  Q+ Q   ELE  +  + GTE+K   S  +  +     +  +   +++KS 
Sbjct: 305  QLELTE-VKSQLIQIQDELEKYITQLDGTEAKLSESQQQLHNKEKVYEKSQLELTEVKSQ 363

Query: 386  WSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGK 445
             ++   +   +    ++N  E    E   Q  NK+ V ++  + E               
Sbjct: 364  LTKTQDDL--EKYVSQLNGTEAKLSESQQQLHNKEKVYEKSQL-ELTEVKSQLTKTQDDL 420

Query: 446  DTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLIEKL 505
            +  ++QL     +  E    +H   N E V E  K Q++ ++    + K    K+   +L
Sbjct: 421  EKYVSQLNGTEAKLSESQQQLH---NKEKVLE--KTQDEFQKVQQIQTKFDQTKN---EL 472

Query: 506  KSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTI-DNFSKVSDSNKEIVRLTEEL 564
             +A+ Q+ +   E+      + K K     K +  QK + +  SK+ ++  E+V+   +L
Sbjct: 473  ATAKSQLNETKTELIQCQSEL-KEKEGELQKYQGTQKELLETQSKLDETQGELVQYQSQL 531

Query: 565  HHLSQKVAELEEEKGNLQ-LHLVDYDSGRMIESDVYK----KMIEMENLAETRLKAISLL 619
            H   Q + ELE+    LQ   L   +    +E++       K  + +N AE      SL 
Sbjct: 532  H---QNLEELEKNICKLQEAELAWKELKFQLETNEELLDKFKFQDKQNQAELGQTKHSLY 588

Query: 620  ESQ-KFDLVQ-ELHILQQKYDEVEDKL-ADISQLQSDQVCSEIKSVHLEEQIDALSASKK 676
            E++ K    Q +LH  Q+ ++  + +L A    L+  Q   +     LE+    L  ++ 
Sbjct: 589  ETKIKLKTSQNQLHKTQEFWESSQSQLVAKEVVLKKYQQDLQDAEKALEDTYSQLQRTQI 648

Query: 677  ELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELL 736
            EL +  +NL   K +L+     L   +E+   K Q+ +     L ++      +   +  
Sbjct: 649  ELGVTRQNLSESKGELFIYKYQLHQSQEE-WEKYQSQLAGTEVLLEEYHSQLKQATEQ-- 705

Query: 737  AKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLE 796
                 + QSK+      +A +Q ++  +    SEL K K     LE S + ++     +E
Sbjct: 706  ---KQQTQSKLTET---EAILQAKEAELTESNSELEKIK---LELERSGSDLQKTHQEVE 756

Query: 797  RKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQ 856
            +   QL    ++KQ+  S+ T  E  L  + A L + +  +EK  LE+E    +LQK +Q
Sbjct: 757  KNQSQLKQAEEQKQQTQSKLTETEAILQAKEAELTESNSELEKIKLELERSGSDLQKTHQ 816

Query: 857  ILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQ----------TQLRDLESN 906
             L +    L  + +D+ +  + L +K  R + +E+E  + Q          ++L   +  
Sbjct: 817  ELQQIQSQLNQTQADLTESNSQLKDKETRWEKSEAELKEIQKSQNKWEISKSELHKTKQE 876

Query: 907  LKRITHEHQTL---IVQKKKEIEDLE---IEFNTQIESAIRDKKVLNEKYEKNIEYVTQL 960
            LKR   ++Q L   +V+   +++  +   +E N+Q++    +    N + ++    + + 
Sbjct: 877  LKRSQLQNQELQIELVESNSQLQQTKTELVESNSQLQQTKTELVESNSQLQQTKTELVES 936

Query: 961  EAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQT-----QSPDYTEQYINEINKLN 1015
             +QLQ+ K  +   N    +L +   EL++ + Q QQT     +S    +Q   E+ + N
Sbjct: 937  NSQLQQTKTELVESN---SQLQQTKTELVESNSQLQQTKTELVESNSQLQQTKTELVESN 993

Query: 1016 ALLKQKDEEIIALNQKINNAQVSYM---SMVSDYESKLAQFTTKLENMEEEMQRVSKQLL 1072
            + L+Q   E++  N ++   +       S     +S L +F T+L   +EE + +  QL 
Sbjct: 994  SQLQQTKTELVESNSQLQQTETLLQKSNSQSQQTKSLLIEFKTQLHQTDEERENMQIQLQ 1053

Query: 1073 DSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIE 1119
            +++   +E+Q   R+ +  +++ +  +   +  +  T+  +I +  E
Sbjct: 1054 ETQAVLQEIQTQWRKTEILLQQSQSQQQNVQKELVGTKSQLIETKSE 1100



 Score =  108 bits (259), Expect = 1e-21
 Identities = 176/886 (19%), Positives = 376/886 (42%), Gaps = 68/886 (7%)

Query: 477  EIAKVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKL- 535
            E+ +V+ QL Q + DE++       I +L   E ++++   ++   NK  +  KS  +L 
Sbjct: 307  ELTEVKSQLIQ-IQDELEKY-----ITQLDGTEAKLSESQQQLH--NKEKVYEKSQLELT 358

Query: 536  KLK-QMQKTIDNFSK-VSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRM 593
            ++K Q+ KT D+  K VS  N    +L+E    L  K    E+     QL L +  S   
Sbjct: 359  EVKSQLTKTQDDLEKYVSQLNGTEAKLSESQQQLHNKEKVYEKS----QLELTEVKSQLT 414

Query: 594  IESDVYKKMIEMENLAETRLKAIS--LLESQKF-----DLVQELHILQQKYDEVEDKLA- 645
               D  +K +   N  E +L      L   +K      D  Q++  +Q K+D+ +++LA 
Sbjct: 415  KTQDDLEKYVSQLNGTEAKLSESQQQLHNKEKVLEKTQDEFQKVQQIQTKFDQTKNELAT 474

Query: 646  ---DISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLEND 702
                +++ +++ +  + +    E ++     ++KEL  +    KLD+ Q  G +   ++ 
Sbjct: 475  AKSQLNETKTELIQCQSELKEKEGELQKYQGTQKEL--LETQSKLDETQ--GELVQYQSQ 530

Query: 703  KEDIMNKLQNYI--QENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFG-IDAKIQE 759
                + +L+  I   +  +L  K  K   E   ELL K   +++   Q + G     + E
Sbjct: 531  LHQNLEELEKNICKLQEAELAWKELKFQLETNEELLDKFKFQDKQN-QAELGQTKHSLYE 589

Query: 760  RDLYIENIESELSK----YKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSE 815
              + ++  +++L K    ++S   +L     V++  +  L+     L     + Q+   E
Sbjct: 590  TKIKLKTSQNQLHKTQEFWESSQSQLVAKEVVLKKYQQDLQDAEKALEDTYSQLQRTQIE 649

Query: 816  YTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQH 875
              +    L      L  +   + +   E E    +L     +L E +  L+ +    QQ 
Sbjct: 650  LGVTRQNLSESKGELFIYKYQLHQSQEEWEKYQSQLAGTEVLLEEYHSQLKQATEQKQQT 709

Query: 876  YNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFN-T 934
             + L E        E+E T+  ++L  ++  L+R   +     +QK  +    E+E N +
Sbjct: 710  QSKLTETEAILQAKEAELTESNSELEKIKLELERSGSD-----LQKTHQ----EVEKNQS 760

Query: 935  QIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVE----ELNKMNLELID 990
            Q++ A   K+    K  +    +   EA+L E  + +E + + +E    +L K + EL  
Sbjct: 761  QLKQAEEQKQQTQSKLTETEAILQAKEAELTESNSELEKIKLELERSGSDLQKTHQELQQ 820

Query: 991  KHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYE--- 1047
               Q  QTQ+ D TE   +++       ++ + E+  + +  N  ++S   +    +   
Sbjct: 821  IQSQLNQTQA-DLTESN-SQLKDKETRWEKSEAELKEIQKSQNKWEISKSELHKTKQELK 878

Query: 1048 -SKLAQFTTKLENMEE--EMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEM 1104
             S+L     ++E +E   ++Q+   +L++S    ++ +  + E + Q+++ K   +    
Sbjct: 879  RSQLQNQELQIELVESNSQLQQTKTELVESNSQLQQTKTELVESNSQLQQTKTELVESNS 938

Query: 1105 NIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKL 1164
             + +T+  ++ S  +        V+              V+   +  Q ++ L E +++L
Sbjct: 939  QLQQTKTELVESNSQLQQTKTELVESNSQLQQTKTEL--VESNSQLQQTKTELVESNSQL 996

Query: 1165 N---TELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELR 1221
                TEL E  +++ Q ETL  +        +  + + K++L Q + E +N+   + E +
Sbjct: 997  QQTKTELVESNSQLQQTETLLQKSNSQSQQTKSLLIEFKTQLHQTDEERENMQIQLQETQ 1056

Query: 1222 SSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQE 1281
            + +     Q  +   E+  Q    ++ + QK     + QL   +S+ E+ L   Q+  ++
Sbjct: 1057 AVLQEI--QTQWRKTEILLQQSQSQQQNVQKELVGTKSQLIETKSELEK-LQYQQAILRD 1113

Query: 1282 ETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEI 1327
              ++  T  ++   +     +  +L  +QE+    +   EI R+E+
Sbjct: 1114 LKSEGKTEYKLLVWEAWYAYQNNNLAEMQERLQKSLKYTEISRTEV 1159



 Score =  103 bits (246), Expect = 5e-20
 Identities = 144/725 (19%), Positives = 312/725 (43%), Gaps = 56/725 (7%)

Query: 851  LQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRI 910
            L K+N+ILL E +  +   +  ++    L E  ++    + E  KY TQL   E+ L   
Sbjct: 283  LGKQNKILLVELEKYK---NQDEKSQLELTEVKSQLIQIQDELEKYITQLDGTEAKLS-- 337

Query: 911  THEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNN 970
              E Q  +  K+K  E  ++E  T+++S +   +   +  EK +  +   EA+L E +  
Sbjct: 338  --ESQQQLHNKEKVYEKSQLEL-TEVKSQLTKTQ---DDLEKYVSQLNGTEAKLSESQQQ 391

Query: 971  IENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQ 1030
            + N     E   K  LEL +  V+ Q T++ D  E+Y++++N   A L +         Q
Sbjct: 392  LHNKEKVYE---KSQLELTE--VKSQLTKTQDDLEKYVSQLNGTEAKLSESQ-------Q 439

Query: 1031 KINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDD 1090
            +++N +   +    D   K+ Q  TK +  + E+     QL ++K    + Q  ++E++ 
Sbjct: 440  QLHNKE-KVLEKTQDEFQKVQQIQTKFDQTKNELATAKSQLNETKTELIQCQSELKEKEG 498

Query: 1091 QIKELKETK---LTFEMNIPKTEGMIIS--STIEPMSDDANNVDXXXXXXXXXXXXLKVQ 1145
            ++++ + T+   L  +  + +T+G ++   S +    ++                 LK Q
Sbjct: 499  ELQKYQGTQKELLETQSKLDETQGELVQYQSQLHQNLEELEKNICKLQEAELAWKELKFQ 558

Query: 1146 EE--EEFIQERSVLQEQS-AKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSK 1202
             E  EE + +     +Q+ A+L       Y   I+L+T   +L       +   +QL +K
Sbjct: 559  LETNEELLDKFKFQDKQNQAELGQTKHSLYETKIKLKTSQNQLHKTQEFWESSQSQLVAK 618

Query: 1203 LEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLS 1262
               L     +L      L  + S  + +   E+  + +Q+L++ + +    +++L     
Sbjct: 619  EVVLKKYQQDLQDAEKALEDTYSQ-LQRTQIELG-VTRQNLSESKGELFIYKYQLHQSQE 676

Query: 1263 AFESKYEQLLDSVQSSTQEETNKIV-TMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIE 1321
             +E KY+  L   +   +E  +++    EQ    Q+KL + E  L+  + +  +  +++E
Sbjct: 677  EWE-KYQSQLAGTEVLLEEYHSQLKQATEQKQQTQSKLTETEAILQAKEAELTESNSELE 735

Query: 1322 ILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSS 1381
             ++ E+E                        + +    ++ Q QS L   E   Q K++ 
Sbjct: 736  KIKLELE------RSGSDLQKTHQEVEKNQSQLKQAEEQKQQTQSKLTETEAILQAKEAE 789

Query: 1382 XXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQL 1441
                           +     L+ THQ EL+  +I  + ++    LT+ N + ++   + 
Sbjct: 790  LTESNSELEKIKLELERSGSDLQKTHQ-ELQ--QIQSQLNQTQADLTESNSQLKDKETRW 846

Query: 1442 VEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIE---ELNVKITES 1498
             + E  ++++  + +++  I + ++H+     +  Q +++  +++L+E   +L    TE 
Sbjct: 847  EKSEAELKEIQ-KSQNKWEISKSELHKTKQELKRSQLQNQELQIELVESNSQLQQTKTEL 905

Query: 1499 VSLNKQ-------VAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASS 1551
            V  N Q       + E N  L++   +  E  + L+  + E+V  N ++   +  +  S+
Sbjct: 906  VESNSQLQQTKTELVESNSQLQQTKTELVESNSQLQQTKTELVESNSQLQQTKTELVESN 965

Query: 1552 SKIQK 1556
            S++Q+
Sbjct: 966  SQLQQ 970



 Score = 49.6 bits (113), Expect = 7e-04
 Identities = 70/412 (16%), Positives = 172/412 (41%), Gaps = 17/412 (4%)

Query: 297  KQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTES 356
            KQ+ E   + ++++ E  ++  A   ELT+    LE +  ++ ++  +L+     +    
Sbjct: 700  KQATEQKQQTQSKLTETEAILQAKEAELTESNSELEKIKLELERSGSDLQKTHQEVEKNQ 759

Query: 357  KAVSSPSKKGSPLISRKSGRNTASKMK-SPWSQLSSETLNQDTDKKINKNEIAKLEMVIQ 415
              +    ++     S+ +      + K +  ++ +SE      + + + +++ K    +Q
Sbjct: 760  SQLKQAEEQKQQTQSKLTETEAILQAKEAELTESNSELEKIKLELERSGSDLQKTHQELQ 819

Query: 416  SLNKDLVDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDV 475
             +   L   +  ++E ++            +  + ++Q    +     S +H     +  
Sbjct: 820  QIQSQLNQTQADLTESNSQLKDKETRWEKSEAELKEIQKSQNKWEISKSELH-----KTK 874

Query: 476  NEIAKVQEQLKQELNDEIKDVN--VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNH 533
             E+ + Q Q  QEL  E+ + N  ++    +L  +  Q+ Q   E+  +N  + + K+  
Sbjct: 875  QELKRSQLQ-NQELQIELVESNSQLQQTKTELVESNSQLQQTKTELVESNSQLQQTKTEL 933

Query: 534  KLKLKQMQKT----IDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYD 589
                 Q+Q+T    +++ S++  +  E+V    +L     ++ E   +    +  LV+ +
Sbjct: 934  VESNSQLQQTKTELVESNSQLQQTKTELVESNSQLQQTKTELVESNSQLQQTKTELVESN 993

Query: 590  SG-RMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADIS 648
            S  +  ++++ +   +++   ET L+  +    Q   L+ E      + DE  + +  I 
Sbjct: 994  SQLQQTKTELVESNSQLQQ-TETLLQKSNSQSQQTKSLLIEFKTQLHQTDEERENM-QIQ 1051

Query: 649  QLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLE 700
              ++  V  EI++   + +I  L  S+ +   V + L   K QL  T  +LE
Sbjct: 1052 LQETQAVLQEIQTQWRKTEI-LLQQSQSQQQNVQKELVGTKSQLIETKSELE 1102



 Score = 40.3 bits (90), Expect = 0.43
 Identities = 34/147 (23%), Positives = 63/147 (42%), Gaps = 8/147 (5%)

Query: 1433 EFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKESEIERVKLIEELN 1492
            E   V+ QL++ +  +E    + +   A    K+ E+       +K  E  +++L E  +
Sbjct: 307  ELTEVKSQLIQIQDELEKYITQLDGTEA----KLSESQQQLHNKEKVYEKSQLELTEVKS 362

Query: 1493 VKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSS 1552
                    L K V++LN       AK +E Q  L N+E        E+T +++ +  +  
Sbjct: 363  QLTKTQDDLEKYVSQLNGT----EAKLSESQQQLHNKEKVYEKSQLELTEVKSQLTKTQD 418

Query: 1553 KIQKHVSFASDTKQGRDEQLDNTMNKE 1579
             ++K+VS  + T+    E      NKE
Sbjct: 419  DLEKYVSQLNGTEAKLSESQQQLHNKE 445


>UniRef50_Q232U4 Cluster: Putative uncharacterized protein; n=1;
            Tetrahymena thermophila SB210|Rep: Putative
            uncharacterized protein - Tetrahymena thermophila SB210
          Length = 1038

 Score =  122 bits (294), Expect = 8e-26
 Identities = 208/1065 (19%), Positives = 443/1065 (41%), Gaps = 115/1065 (10%)

Query: 555  KEIVRLTEELHHLSQKVAELEEE-KGNLQLHLVDYDS----GRMIESDVYKKMIEM---- 605
            K++ +LT+ +  L+ K  E E+  K  +Q +    D     G  I +  YK+ ++     
Sbjct: 14   KKVAQLTKVIFFLNTKNDEYEQNLKAVVQAYEQQLDQTVKEGNQIITK-YKEALDKASKN 72

Query: 606  ENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLE 665
            E+LA   +K    ++ +K    QE    +QK +E E +L      + D    E +   ++
Sbjct: 73   EDLANQVMKMKQQIDQEKQQSQQEFTKYKQKCEEKEGQLIRECAKKIDTYKQECEGFKVK 132

Query: 666  EQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLE 725
              I+ L+ +   L  VI N + +K+     + D   ++ +  N L   +++ +DL D+LE
Sbjct: 133  --IEQLTTN---LDKVINNSESNKKNHQKELADYVKEQNEKYNDL---LKKKLDLEDQLE 184

Query: 726  KMSAE------KISELLAKI-----NHEEQSKIQTQ----------FGIDAKIQERDLYI 764
            K  AE      KI EL  KI     N + QS+   +            ++ K +E    I
Sbjct: 185  KRDAEIAQLKKKIDELNKKIMDDLKNQKGQSQQMLEELKKNYENKIADLEGKNKELLQKI 244

Query: 765  ENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELV 824
            +++E+E+   + ++   E  +  + D R  L++  ++    +QE+QK      +++ +  
Sbjct: 245  QSLEAEIQSLRMQLNNRETELKTVSDERNQLKKMTERQALQIQEQQKEIDGLKVEKQQNF 304

Query: 825  NRLAVLMDHDRVVEKQLLEIEHENKELQKKNQI---------------LLEENQNL---Q 866
             ++  L   ++ +EK++ + + +  +  K N +               L ++N+ +   +
Sbjct: 305  EKIKQLEAANQALEKKIKDYQDQLDKYGKDNNMKDSEIGTLRKQFEKTLFDKNEEIKGVR 364

Query: 867  ISLSDMQQHYNALVEKANRTDL-AESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEI 925
              L ++Q+ Y+ L  +   T    E+E+ +   Q+ DL   +K +  E  +L    + ++
Sbjct: 365  AQLMELQKQYDLLQIQLKTTQAEREAENREKDAQIADLLKQVKALQEEIASLSNNSEGQL 424

Query: 926  EDLEIEFNTQIESAIRDKKVLNEKYEKNI-----EYVTQLEAQLQEYKNNIENLNMNVEE 980
            + L+ +   +       K+ L E Y   +     +Y+ Q+E   ++Y+  I  L     +
Sbjct: 425  KQLQEKLKQKTLEFEDSKRTLIEDYSNQLSAQEKKYLQQIEDLKRDYEQKIRQLTQENSQ 484

Query: 981  LNKMNLELIDKHVQKQQTQSPDYTEQYINEI----NKLNALLKQKDEEIIALNQKINNAQ 1036
                 ++  ++ ++K + +  +   QY N       KL   ++++ E+I  LN++I   Q
Sbjct: 485  KEASLIQKYEEQLKKLRDEMDEQKRQYENNAGSMEKKLQQTIEKQQEQINGLNKQITELQ 544

Query: 1037 VSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELK 1096
                ++ +    K      +   ++   Q +S   +  +Q N +     RE + +I+ LK
Sbjct: 545  TRIQNLENTINQKDLDINQRDSMIQSLKQTISDLEIKFQQQNADGSSRQRELEIEIQNLK 604

Query: 1097 ETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSV 1156
            ++    E              IE + ++AN               +++Q E E    RS 
Sbjct: 605  KSLEDQERK--------YRDEIERLKNNANG------ELSDTIARMRIQYEGEMNAMRSQ 650

Query: 1157 LQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLST 1216
             Q +  +L  +  E      +++ L  +L       Q   + L SKL+Q   E ++ +  
Sbjct: 651  HQSEITRLERQKNE------EIKNLRDQLNLLKEQMQNDSSDLLSKLKQREQEYEDQIKQ 704

Query: 1217 VAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQ 1276
            + +  +     ++++        +Q L Q +  ++    +LR QL   E +  + L  +Q
Sbjct: 705  INQRHNYELKLIEEKN-------QQMLNQTKTYYEDELKKLREQL---EFEKTKALQKLQ 754

Query: 1277 SSTQEETNKI-VTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFX 1335
               + E  K+  T E   +  +K  DK+     L E+  +   ++++L+ ++EDE+ A  
Sbjct: 755  DEKEAEIAKLKQTHEDKLTSLSKNFDKQ-----LAERQQEFETKMKLLQKKVEDEEKA-H 808

Query: 1336 XXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRV 1395
                           D  ++N+  KQ  ++ I +++ E   LK+                
Sbjct: 809  FSTKEELKTTQTNLTDQISQNKDLKQKTDKQIFDMSAEIKALKQQMEELIQQQTEALL-A 867

Query: 1396 NDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEK 1455
             D + + ++  +Q   K+ E+ +K +E  +   +  ++ E + Q  +E+  ++E    EK
Sbjct: 868  RDQQVEGIKRDYQ--RKEEEVLRKANE--LVNRKIAEQLEFIEQMKIEF-NQVESALTEK 922

Query: 1456 ESELAILRLKMHENANHYETMQKESEIERVKLIE-ELNVKITESVSLNKQVAELNKALEE 1514
               L      + +     +   +  +IE +KL++ E+  K  E   LN+Q+      L  
Sbjct: 923  YVRLENDYNDLQQMFE--DRPSRPEDIETIKLLQAEIMRKEQEIGKLNEQMKFFKLELIN 980

Query: 1515 EVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVS 1559
                 N+M  A  N  + ++   D+       V   S+K+    S
Sbjct: 981  RENNYNKMFNA--NPNVGVMNPLDQKGQTAMRVLPQSNKLISQTS 1023



 Score =  118 bits (285), Expect = 1e-24
 Identities = 158/796 (19%), Positives = 341/796 (42%), Gaps = 48/796 (6%)

Query: 771  LSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVL 830
            LS    ++C+    +A +    + L  K D+    L+   +AY +   Q  +  N+  ++
Sbjct: 5    LSDLHHKMCK---KVAQLTKVIFFLNTKNDEYEQNLKAVVQAYEQQLDQTVKEGNQ--II 59

Query: 831  MDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQ----HYNALVEKANRT 886
              +   ++K     +  N+ ++ K QI  E+ Q+ Q      Q+        + E A + 
Sbjct: 60   TKYKEALDKASKNEDLANQVMKMKQQIDQEKQQSQQEFTKYKQKCEEKEGQLIRECAKKI 119

Query: 887  DLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVL 946
            D  + E   ++ ++  L +NL ++ +  ++     +KE+ D   E N +    ++ K  L
Sbjct: 120  DTYKQECEGFKVKIEQLTTNLDKVINNSESNKKNHQKELADYVKEQNEKYNDLLKKKLDL 179

Query: 947  NEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQ 1006
             ++ EK    + QL+ ++ E    I +   N +  ++  LE + K+ + +        ++
Sbjct: 180  EDQLEKRDAEIAQLKKKIDELNKKIMDDLKNQKGQSQQMLEELKKNYENKIADLEGKNKE 239

Query: 1007 YINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQR 1066
             + +I  L A       EI +L  ++NN +   +  VSD  ++L + T +     +E Q+
Sbjct: 240  LLQKIQSLEA-------EIQSLRMQLNNRETE-LKTVSDERNQLKKMTERQALQIQEQQK 291

Query: 1067 VSKQLLDSKQHN----EELQILVREQDDQIKELKE--TKLTFEMNIPKTEGMIISSTIEP 1120
                L   KQ N    ++L+   +  + +IK+ ++   K   + N+  +E   +    E 
Sbjct: 292  EIDGLKVEKQQNFEKIKQLEAANQALEKKIKDYQDQLDKYGKDNNMKDSEIGTLRKQFEK 351

Query: 1121 MSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLET 1180
               D N               L+ Q +   IQ ++   E+ A+   +  +    + Q++ 
Sbjct: 352  TLFDKNE---EIKGVRAQLMELQKQYDLLQIQLKTTQAEREAENREKDAQIADLLKQVKA 408

Query: 1181 LNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWK 1240
            L  E+      ++ Q+ QL+ KL+Q   E ++   T+ E  S+  SA +++  +  E  K
Sbjct: 409  LQEEIASLSNNSEGQLKQLQEKLKQKTLEFEDSKRTLIEDYSNQLSAQEKKYLQQIEDLK 468

Query: 1241 QHLAQREADFQKTEHELRVQL-SAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKL 1299
            +   Q+     +   +    L   +E + ++L D +    ++  N   +ME+   LQ  +
Sbjct: 469  RDYEQKIRQLTQENSQKEASLIQKYEEQLKKLRDEMDEQKRQYENNAGSMEK--KLQQTI 526

Query: 1300 QDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAF-XXXXXXXXXXXXXXXXDLRTENQS 1358
            + ++E +  L ++  ++  +I+ L + I  + +                   +++ + Q+
Sbjct: 527  EKQQEQINGLNKQITELQTRIQNLENTINQKDLDINQRDSMIQSLKQTISDLEIKFQQQN 586

Query: 1359 YKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRV-NDAEAKVLELTHQLELK---DS 1414
                  Q  L I  +N  LKKS             R+ N+A  ++ +   ++ ++   + 
Sbjct: 587  ADGSSRQRELEIEIQN--LKKSLEDQERKYRDEIERLKNNANGELSDTIARMRIQYEGEM 644

Query: 1415 EIYQKTHEYTITL--TQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANH 1472
               +  H+  IT    Q+N+E +N+R QL   ++++++   +    L+ L+ +  E  + 
Sbjct: 645  NAMRSQHQSEITRLERQKNEEIKNLRDQLNLLKEQMQN---DSSDLLSKLKQREQEYEDQ 701

Query: 1473 YETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEE-EVAKTNEMQTALENQEI 1531
             + + +    E +KLIEE N ++        +  EL K  E+ E  KT  +Q   + +E 
Sbjct: 702  IKQINQRHNYE-LKLIEEKNQQMLNQTKTYYE-DELKKLREQLEFEKTKALQKLQDEKEA 759

Query: 1532 EIVTL----NDEITNL 1543
            EI  L     D++T+L
Sbjct: 760  EIAKLKQTHEDKLTSL 775



 Score = 98.3 bits (234), Expect = 2e-18
 Identities = 192/963 (19%), Positives = 420/963 (43%), Gaps = 106/963 (11%)

Query: 147  LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXX 206
            L    K +D A  V+++K +I +      QE    K +  E + +               
Sbjct: 66   LDKASKNEDLANQVMKMKQQIDQEKQQSQQEFTKYKQKCEEKEGQLIRECAKKIDTYKQE 125

Query: 207  XXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFE 266
                    +Q  T + +     E+  K+ ++ L   ++ ++ + + L +    LE    +
Sbjct: 126  CEGFKVKIEQLTTNLDKVINNSESNKKNHQKELADYVKEQNEKYNDLLKKKLDLEDQLEK 185

Query: 267  ISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEK-GSLEIANMTELT 325
               E ++L +++++               ++Q +E   E K   E K   LE  N  EL 
Sbjct: 186  RDAEIAQLKKKIDELNKKIMDDLKNQKGQSQQMLE---ELKKNYENKIADLEGKNK-ELL 241

Query: 326  KKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKSP 385
            +KI+ LE    +I+    +L N+     TE K VS    +   +  R++       ++  
Sbjct: 242  QKIQSLE---AEIQSLRMQLNNR----ETELKTVSDERNQLKKMTERQA-------LQIQ 287

Query: 386  WSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISE--KDTXXXXXXXXXX 443
              Q   + L    +K+ N  +I +LE   Q+L K + D +  + +  KD           
Sbjct: 288  EQQKEIDGLK--VEKQQNFEKIKQLEAANQALEKKIKDYQDQLDKYGKDNNMKDSEIGTL 345

Query: 444  GKDTLIAQLQLEHQQHMEGPSLIHVGTNTE-DVNEIAKVQEQLKQELNDEIKDVNVKDLI 502
             K     +   +  + ++G     +    + D+ +I     Q ++E  +  KD  + DL+
Sbjct: 346  RKQ--FEKTLFDKNEEIKGVRAQLMELQKQYDLLQIQLKTTQAEREAENREKDAQIADLL 403

Query: 503  EKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTI--DNFSKVSDSNKEIVRL 560
            +++K+ +E+I  L++  +   K + +      L+ +  ++T+  D  +++S   K+ ++ 
Sbjct: 404  KQVKALQEEIASLSNNSEGQLKQLQEKLKQKTLEFEDSKRTLIEDYSNQLSAQEKKYLQQ 463

Query: 561  TEEL-HHLSQKVAELEEEKGNLQLHLVD-YDSG-RMIESDVYKKMIEMENLA---ETRL- 613
             E+L     QK+ +L +E    +  L+  Y+   + +  ++ ++  + EN A   E +L 
Sbjct: 464  IEDLKRDYEQKIRQLTQENSQKEASLIQKYEEQLKKLRDEMDEQKRQYENNAGSMEKKLQ 523

Query: 614  KAISLLESQKFDLVQELHILQQKYDEVEDKL--ADISQLQSDQVCSEIK------SVHLE 665
            + I   + Q   L +++  LQ +   +E+ +   D+   Q D +   +K       +  +
Sbjct: 524  QTIEKQQEQINGLNKQITELQTRIQNLENTINQKDLDINQRDSMIQSLKQTISDLEIKFQ 583

Query: 666  EQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLE 725
            +Q    S+ ++EL + I+NLK        +++D E    D + +L+N    N +L+D + 
Sbjct: 584  QQNADGSSRQRELEIEIQNLK-------KSLEDQERKYRDEIERLKN--NANGELSDTIA 634

Query: 726  KMSAEKISELLA-KINHE-EQSKIQTQFGIDAK--IQERDLYIENIESE----LSKYKSR 777
            +M  +   E+ A +  H+ E ++++ Q   + K    + +L  E ++++    LSK K R
Sbjct: 635  RMRIQYEGEMNAMRSQHQSEITRLERQKNEEIKNLRDQLNLLKEQMQNDSSDLLSKLKQR 694

Query: 778  ICRLEESIAVMEDR-RYSL-------ERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAV 829
                E+ I  +  R  Y L       ++  +Q  +Y +++ K   E    E E    L  
Sbjct: 695  EQEYEDQIKQINQRHNYELKLIEEKNQQMLNQTKTYYEDELKKLREQL--EFEKTKALQK 752

Query: 830  LMDHDRVVEKQLLEIEHENK--ELQKK-NQILLEENQNLQISLSDMQQ--------HYNA 878
            L D ++  E   L+  HE+K   L K  ++ L E  Q  +  +  +Q+        H++ 
Sbjct: 753  LQD-EKEAEIAKLKQTHEDKLTSLSKNFDKQLAERQQEFETKMKLLQKKVEDEEKAHFST 811

Query: 879  LVE----KANRTD-LAESESTKYQT--QLRDLESNLKRITHEHQTLIVQ-------KKKE 924
              E    + N TD +++++  K +T  Q+ D+ + +K +  + + LI Q       + ++
Sbjct: 812  KEELKTTQTNLTDQISQNKDLKQKTDKQIFDMSAEIKALKQQMEELIQQQTEALLARDQQ 871

Query: 925  IEDLEIEFNTQIESAIRD-KKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNK 983
            +E ++ ++  + E  +R   +++N K  + +E++ Q++ +  + ++ +    + +E  N 
Sbjct: 872  VEGIKRDYQRKEEEVLRKANELVNRKIAEQLEFIEQMKIEFNQVESALTEKYVRLE--ND 929

Query: 984  MNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMV 1043
             N       +Q+     P   E  I  I  L A + +K++EI  LN+++   ++  ++  
Sbjct: 930  YN------DLQQMFEDRPSRPED-IETIKLLQAEIMRKEQEIGKLNEQMKFFKLELINRE 982

Query: 1044 SDY 1046
            ++Y
Sbjct: 983  NNY 985


>UniRef50_A0D4V9 Cluster: Chromosome undetermined scaffold_38, whole
            genome shotgun sequence; n=5; Oligohymenophorea|Rep:
            Chromosome undetermined scaffold_38, whole genome shotgun
            sequence - Paramecium tetraurelia
          Length = 1636

 Score =  122 bits (294), Expect = 8e-26
 Identities = 209/1085 (19%), Positives = 448/1085 (41%), Gaps = 69/1085 (6%)

Query: 480  KVQEQLKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVK--------- 530
            K++++LK+   D +KD N  +L+ KL   E + + L      A  N+ ++K         
Sbjct: 495  KLEQELKEARQDSLKDKN--NLLMKLAQVESEKSDLELREQVARDNLEELKIQKEQVERD 552

Query: 531  -----SNHKLKL-KQMQKTIDNFSKVSDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLH 584
                  N K++L +Q+Q+      K  + NK++ R T   +   +K   L E+K      
Sbjct: 553  LKLESENEKIELTRQIQELKGQVLKAEEFNKDMERNTLFGNSEFEKERALLEQKITFFEK 612

Query: 585  LVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKL 644
            LV+  + + ++     K +  E+  +++ +     ++ +  L Q+L  LQ+K +E+E++L
Sbjct: 613  LVNEMNAKEVDYQNEIKNLRKEHSLQSKDQQTKSDQTVR-QLQQKLSDLQEKLNEMENEL 671

Query: 645  AD-ISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIK-DLEND 702
             +  S  ++D    E K   L +Q    +   + L   I   K ++EQ+   +K D  N 
Sbjct: 672  IEKESNFENDFKKFEHKERSLTKQNLEQNEQIQALTREIREYKRNEEQMQQMLKSDANNQ 731

Query: 703  KEDIMNKLQNY--IQENMDLTDKLEKMSAEKISELL-AKINHEEQSKIQTQFGIDAKIQE 759
              +++ K+Q    + +  D   K  K  +EK   L+  K+   E    + +  I+   + 
Sbjct: 732  VNELLEKVQGLEDLIKTKDDQLKQAKSHSEKDKALMQQKMEFMEVQLDEYKKQIEENKKS 791

Query: 760  RDLYIENIE--SELSKYKSRICRLEE-------SIAVMEDRRYSLERKADQLGSYLQEKQ 810
             +  ++  E  S  S YK    ++ +        +  +E+   S++++  Q    L E+ 
Sbjct: 792  HEAIMKAFENSSNESTYKIDAAKMNDLREQHKRDLKNIENEYESVKKRLQQQVDQLNERN 851

Query: 811  KAYS-EYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQ-KKNQILLEENQNLQIS 868
                 +   +  +L+N +  L +  +  E+Q  ++  +NK L  +K  IL E+    Q  
Sbjct: 852  SELELKVKFETGDLINEIENLKEQLQTSEEQKNKLLEQNKTLDGQKLSILKEQELRYQKK 911

Query: 869  LSDMQQHYN-ALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIED 927
            +  ++Q  + A  + A   + A++++ +  TQL+    N   I  E     + ++KE  D
Sbjct: 912  IKQLEQAMDEADTKTAREVNQAQAKAEESLTQLK----NFYEIERERLERRICEEKEKSD 967

Query: 928  LEIEFNTQIESAIRDKKVLNEKYEKNIEYV-TQLEAQLQEYKNNIENLNMNVEELNKMNL 986
               +F    E      +   + YE+ IE +   L  Q+Q+Y N I+  +  +  L +  +
Sbjct: 968  K--KFQAAQEEFYHKLRETEQNYEEEIETLKDDLRDQVQQYTNTIQQYDHEI-ALKQQTI 1024

Query: 987  ELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDY 1046
            E+ +KH++       +  EQ I+  N  N  L+Q+        + + +      S +++ 
Sbjct: 1025 EIFEKHIK-------EIKEQLISLQNNNNTTLEQQMNSFTTERKSLISKNDVLSSQLNNL 1077

Query: 1047 ESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNI 1106
            + +      K + +E E  R  +Q    +Q  +E Q   RE  D+++E K+ +L  +MN 
Sbjct: 1078 QKEHMALQQKKDLLENEKTRKEQQF---EQSRKEWQEEKRELIDRLEETKQ-RLQ-KMND 1132

Query: 1107 PKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNT 1166
               E  I       ++   N                +    +E I+++    E S +L  
Sbjct: 1133 EFLEKKIEYGRETALTQQQNEFLQKKIEDLQKQIDTQQSRFDEKIKQQK--NEYSVELEQ 1190

Query: 1167 ELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISS 1226
            +L+    +   +ET   ++      N+ Q N+  S LE+        L  +   ++ + S
Sbjct: 1191 KLERAQEEKTAIETKYEKIKKQLKENEYQYNKQASTLEREKAILTEKLGQLDSRKNELES 1250

Query: 1227 AVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKI 1286
             +      +A+       Q  A+ +  + EL  +   F  + EQ  +  +  T  E +K 
Sbjct: 1251 KIKDESASVAQYQTALREQIAAEKKSLQQELE-KYKQFNLQLEQ--EKSEIHTSYERDKA 1307

Query: 1287 VTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXX 1346
            +   +   L+ + +  ++ L +  +K+   +  ++  RS  +DE+               
Sbjct: 1308 LWEGKFQFLEQQKEQAKQDLMDALKKFEMTLMHLQRARSNEKDEQE--NNLNELLLSVER 1365

Query: 1347 XXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELT 1406
                 +   NQ+++++ +     I     ++K                   +E K  E+ 
Sbjct: 1366 KYQSQIEEANQTHQRIVQDYEDKIRRLQKEVKTHRDKILIDQHGKIGNQLLSEKKFAEML 1425

Query: 1407 HQLELKDSEI--YQKTHEYTITLTQR--NDEFENVRQQLVEYEKRIEDLTYEKES---EL 1459
               +    EI   ++  +Y I   Q+    E EN++ ++VE E + +++  ++ +   E 
Sbjct: 1426 DNEKRLQQEIENIKQDRDYKIFEYQKMLEQERENLKAKIVELETKYKEVENKRSTLIFEF 1485

Query: 1460 AILRLKMHENANHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKT 1519
               R K + + +H   ++ E   +  KL ++    + E+  L  +     +++      +
Sbjct: 1486 EKERAKWNLDRDHLNNIKTELSDQLEKLSDKKEQLLRENEKLKNEQRATRRSVAAHNMTS 1545

Query: 1520 NEMQT 1524
            N ++T
Sbjct: 1546 NNIKT 1550



 Score =  121 bits (291), Expect = 2e-25
 Identities = 219/1099 (19%), Positives = 454/1099 (41%), Gaps = 110/1099 (10%)

Query: 508  AEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQ---KTIDNFSKVSDSNKEIVRLTEEL 564
            A E   +L  E+  A ++ +K K+N  +KL Q++     ++   +V+  N E +++ +E 
Sbjct: 489  AFETQKKLEQELKEARQDSLKDKNNLLMKLAQVESEKSDLELREQVARDNLEELKIQKEQ 548

Query: 565  HHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENL-AETRLKAISLLESQK 623
                 K+ E E EK  L   + +   G++++++ + K +E   L   +  +    L  QK
Sbjct: 549  VERDLKL-ESENEKIELTRQIQEL-KGQVLKAEEFNKDMERNTLFGNSEFEKERALLEQK 606

Query: 624  F----DLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELA 679
                  LV E++  +  Y      L     LQS     + KS     Q+    +  +E  
Sbjct: 607  ITFFEKLVNEMNAKEVDYQNEIKNLRKEHSLQSKD--QQTKSDQTVRQLQQKLSDLQEKL 664

Query: 680  LVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKI 739
              +EN  ++KE       + END +   +K ++  ++N++  ++++ ++ E I E   K 
Sbjct: 665  NEMENELIEKE------SNFENDFKKFEHKERSLTKQNLEQNEQIQALTRE-IREY--KR 715

Query: 740  NHEE-----QSKIQTQFG-IDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRY 793
            N E+     +S    Q   +  K+Q  +  I+  + +L + KS     E+  A+M+ +  
Sbjct: 716  NEEQMQQMLKSDANNQVNELLEKVQGLEDLIKTKDDQLKQAKS---HSEKDKALMQQKME 772

Query: 794  SLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQK 853
             +E + D+    ++E +K++       +   N     +D  ++ + +    E   ++L+ 
Sbjct: 773  FMEVQLDEYKKQIEENKKSHEAIMKAFENSSNESTYKIDAAKMNDLR----EQHKRDLKN 828

Query: 854  KNQILLEENQNLQISLSDMQQHYNALVEKAN-RTDLAESESTKYQTQLRDLESNLKRITH 912
                     + LQ  +  + +  + L  K    T    +E    + QL+  E    ++  
Sbjct: 829  IENEYESVKKRLQQQVDQLNERNSELELKVKFETGDLINEIENLKEQLQTSEEQKNKLLE 888

Query: 913  EHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIE 972
            +++TL  QK   +++ E+ +  +I+     ++ ++E   K    V Q +A+ +E    ++
Sbjct: 889  QNKTLDGQKLSILKEQELRYQKKIKQL---EQAMDEADTKTAREVNQAQAKAEESLTQLK 945

Query: 973  NL-NMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQK 1031
            N   +  E L +   E  +K  +K Q    ++        +KL    +  +EEI  L   
Sbjct: 946  NFYEIERERLERRICEEKEKSDKKFQAAQEEF-------YHKLRETEQNYEEEIETLKDD 998

Query: 1032 INNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQ 1091
            + +    Y + +  Y+ ++A     +E  E+ ++ + +QL+  + +N             
Sbjct: 999  LRDQVQQYTNTIQQYDHEIALKQQTIEIFEKHIKEIKEQLISLQNNN------------- 1045

Query: 1092 IKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXL---KVQEEE 1148
                  T L  +MN   TE   + S  + +S   NN+             L   K ++E+
Sbjct: 1046 -----NTTLEQQMNSFTTERKSLISKNDVLSSQLNNLQKEHMALQQKKDLLENEKTRKEQ 1100

Query: 1149 EFIQERSVLQEQSAKLNTELQECYTKIIQL--ETLNTELT-GHDVVNQEQINQ-LKSKLE 1204
            +F Q R   QE+  +L   L+E   ++ ++  E L  ++  G +    +Q N+ L+ K+E
Sbjct: 1101 QFEQSRKEWQEEKRELIDRLEETKQRLQKMNDEFLEKKIEYGRETALTQQQNEFLQKKIE 1160

Query: 1205 ----QLNTENDNLLSTVAELRSSISSAVDQR---------GFEIA-ELWKQHLAQREADF 1250
                Q++T+       + + ++  S  ++Q+           E   E  K+ L + E  +
Sbjct: 1161 DLQKQIDTQQSRFDEKIKQQKNEYSVELEQKLERAQEEKTAIETKYEKIKKQLKENEYQY 1220

Query: 1251 QKTEHELRVQLSAFESKYEQL---LDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLR 1307
             K    L  + +    K  QL    + ++S  ++E+  +   +  T+L+ ++  +++ L+
Sbjct: 1221 NKQASTLEREKAILTEKLGQLDSRKNELESKIKDESASVAQYQ--TALREQIAAEKKSLQ 1278

Query: 1308 NLQEKYADVINQIEILRSEI----EDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQ-M 1362
               EKY     Q+E  +SEI    E +K  +                DL    + ++  +
Sbjct: 1279 QELEKYKQFNLQLEQEKSEIHTSYERDKALWEGKFQFLEQQKEQAKQDLMDALKKFEMTL 1338

Query: 1363 QEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQ--KT 1420
                    NE++ Q    +            ++ +A      +    E K   + +  KT
Sbjct: 1339 MHLQRARSNEKDEQENNLNELLLSVERKYQSQIEEANQTHQRIVQDYEDKIRRLQKEVKT 1398

Query: 1421 HEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQKES 1480
            H   I +    D+   +  QL+  +K  E L  EK  +  I  +K   +   +E  QK  
Sbjct: 1399 HRDKILI----DQHGKIGNQLLSEKKFAEMLDNEKRLQQEIENIKQDRDYKIFE-YQKML 1453

Query: 1481 EIERVKLIEELNVKITESVSLNKQVAELNKAL----EEEVAKTNEMQTALENQEIEIVTL 1536
            E ER    E L  KI E  +  K+V      L    E+E AK N  +  L N + E+   
Sbjct: 1454 EQER----ENLKAKIVELETKYKEVENKRSTLIFEFEKERAKWNLDRDHLNNIKTELSDQ 1509

Query: 1537 NDEITNLQNMVRASSSKIQ 1555
             +++++ +  +   + K++
Sbjct: 1510 LEKLSDKKEQLLRENEKLK 1528



 Score =  105 bits (253), Expect = 8e-21
 Identities = 202/1070 (18%), Positives = 466/1070 (43%), Gaps = 104/1070 (9%)

Query: 246  KDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCE 305
            K+V   + ++  + L+ AR +   + + L  +L Q              +A+ ++E    
Sbjct: 486  KNVAFETQKKLEQELKEARQDSLKDKNNLLMKLAQVESEKSDLELREQ-VARDNLEELKI 544

Query: 306  EKTEIEEKGSLEIAN-MTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSK 364
            +K ++E    LE  N   ELT++I+ L+    +  + NK++E       +E +   +  +
Sbjct: 545  QKEQVERDLKLESENEKIELTRQIQELKGQVLKAEEFNKDMERNTLFGNSEFEKERALLE 604

Query: 365  KGSPLISRKSGRNTASKM--KSPWSQLSSETLNQDTDKKINKNE-IAKLEMVIQSLNKDL 421
            +      +      A ++  ++    L  E   Q  D++   ++ + +L+  +  L + L
Sbjct: 605  QKITFFEKLVNEMNAKEVDYQNEIKNLRKEHSLQSKDQQTKSDQTVRQLQQKLSDLQEKL 664

Query: 422  VDKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPS--LIHVGTNTEDVNEIA 479
             + E  + EK++           K+  + +  LE  + ++  +  +     N E + ++ 
Sbjct: 665  NEMENELIEKESNFENDFKKFEHKERSLTKQNLEQNEQIQALTREIREYKRNEEQMQQML 724

Query: 480  K------VQEQLK--QELNDEIKDVN-----VKDLIEKLKSAEEQITQLND-EIDAANKN 525
            K      V E L+  Q L D IK  +      K   EK K+  +Q  +  + ++D   K 
Sbjct: 725  KSDANNQVNELLEKVQGLEDLIKTKDDQLKQAKSHSEKDKALMQQKMEFMEVQLDEYKKQ 784

Query: 526  MIKVKSNHKLKLKQMQKTID------NFSKVSDSNKEIVRLTEELHH--------LSQKV 571
            + + K +H+  +K  + + +      + +K++D  ++  R  + + +        L Q+V
Sbjct: 785  IEENKKSHEAIMKAFENSSNESTYKIDAAKMNDLREQHKRDLKNIENEYESVKKRLQQQV 844

Query: 572  AELEEEKGNLQLHLVDYDSGRMI-ESDVYKKMIEMENLAETRL---------KAISLLES 621
             +L E    L+L  V +++G +I E +  K+ ++     + +L         + +S+L+ 
Sbjct: 845  DQLNERNSELELK-VKFETGDLINEIENLKEQLQTSEEQKNKLLEQNKTLDGQKLSILKE 903

Query: 622  QKFDLVQELHILQQKYDEVEDKLA-DISQLQS--DQVCSEIKSVH-LE-EQIDALSASKK 676
            Q+    +++  L+Q  DE + K A +++Q Q+  ++  +++K+ + +E E+++     +K
Sbjct: 904  QELRYQKKIKQLEQAMDEADTKTAREVNQAQAKAEESLTQLKNFYEIERERLERRICEEK 963

Query: 677  ELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMD-LTDKLEKMSAE-KISE 734
            E +   +  +  +E+ Y  +++ E + E+ +  L++ +++ +   T+ +++   E  + +
Sbjct: 964  EKS--DKKFQAAQEEFYHKLRETEQNYEEEIETLKDDLRDQVQQYTNTIQQYDHEIALKQ 1021

Query: 735  LLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICR---LEESIAVMEDR 791
               +I  +   +I+ Q  I  +        + + S  ++ KS I +   L   +  ++  
Sbjct: 1022 QTIEIFEKHIKEIKEQL-ISLQNNNNTTLEQQMNSFTTERKSLISKNDVLSSQLNNLQKE 1080

Query: 792  RYSLERKADQLGSYLQEKQKAYS----EYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHE 847
              +L++K D L +    K++ +     E+  ++ EL++RL       + +  + LE   +
Sbjct: 1081 HMALQQKKDLLENEKTRKEQQFEQSRKEWQEEKRELIDRLEETKQRLQKMNDEFLE---K 1137

Query: 848  NKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNL 907
              E  ++  +  ++N+ LQ  + D+Q+  +   +++   +  + +  +Y  +L   E  L
Sbjct: 1138 KIEYGRETALTQQQNEFLQKKIEDLQKQIDT--QQSRFDEKIKQQKNEYSVEL---EQKL 1192

Query: 908  KRITHEHQTLIVQK----KKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQ 963
            +R   E +T I  K    KK++++ E ++N Q  +  R+K +L EK  +      +LE++
Sbjct: 1193 ER-AQEEKTAIETKYEKIKKQLKENEYQYNKQASTLEREKAILTEKLGQLDSRKNELESK 1251

Query: 964  LQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDE 1023
            +++   ++      + E      + + + ++K + Q     EQ  +EI+      K   E
Sbjct: 1252 IKDESASVAQYQTALREQIAAEKKSLQQELEKYK-QFNLQLEQEKSEIHTSYERDKALWE 1310

Query: 1024 -EIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQ 1082
             +   L Q+   A+   M  +  +E  L        N ++E +    +LL S +   + Q
Sbjct: 1311 GKFQFLEQQKEQAKQDLMDALKKFEMTLMHLQRARSNEKDEQENNLNELLLSVERKYQSQ 1370

Query: 1083 I---------LVREQDDQIKEL-KETKLTFEMNIPKTEGMIISSTIEP-----MSDDANN 1127
            I         +V++ +D+I+ L KE K   +  +    G I +  +       M D+   
Sbjct: 1371 IEEANQTHQRIVQDYEDKIRRLQKEVKTHRDKILIDQHGKIGNQLLSEKKFAEMLDNEKR 1430

Query: 1128 VDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTK----IIQLETLNT 1183
            +                + ++   QER  L+ +  +L T+ +E   K    I + E    
Sbjct: 1431 LQQEIENIKQDRDYKIFEYQKMLEQERENLKAKIVELETKYKEVENKRSTLIFEFEKERA 1490

Query: 1184 ELT-GHDVVNQ------EQINQLKSKLEQLNTENDNLLSTVAELRSSISS 1226
            +     D +N       +Q+ +L  K EQL  EN+ L +     R S+++
Sbjct: 1491 KWNLDRDHLNNIKTELSDQLEKLSDKKEQLLRENEKLKNEQRATRRSVAA 1540



 Score =  105 bits (253), Expect = 8e-21
 Identities = 195/942 (20%), Positives = 399/942 (42%), Gaps = 128/942 (13%)

Query: 689  KEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKIS-ELLAKINHEEQSKI 747
            K   + T K LE   +++    Q+ +++  +L  KL ++ +EK   EL  ++  +   ++
Sbjct: 486  KNVAFETQKKLE---QELKEARQDSLKDKNNLLMKLAQVESEKSDLELREQVARDNLEEL 542

Query: 748  QTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQ 807
            + Q     +  ERDL +E+ E+E  +   +I  L+  +   E+    +ER     G+   
Sbjct: 543  KIQ----KEQVERDLKLES-ENEKIELTRQIQELKGQVLKAEEFNKDMERNT-LFGNSEF 596

Query: 808  EKQKAYSEYTIQE-DELVNRL-AVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNL 865
            EK++A  E  I   ++LVN + A  +D+   ++    E   ++K+ Q K+   + +   L
Sbjct: 597  EKERALLEQKITFFEKLVNEMNAKEVDYQNEIKNLRKEHSLQSKDQQTKSDQTVRQ---L 653

Query: 866  QISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEI 925
            Q  LSD+Q+  N +       +L E ES        + E++ K+  H+ ++L  Q     
Sbjct: 654  QQKLSDLQEKLNEM-----ENELIEKES--------NFENDFKKFEHKERSLTKQN---- 696

Query: 926  EDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMN 985
                +E N QI++  R+ +    +Y++N E   Q++  L+   NN   +N  +E++  + 
Sbjct: 697  ----LEQNEQIQALTREIR----EYKRNEE---QMQQMLKSDANN--QVNELLEKVQGLE 743

Query: 986  LELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSD 1045
              +  K  Q +Q +S    ++ + +  K+  +  Q DE      ++I   + S+ +++  
Sbjct: 744  DLIKTKDDQLKQAKSHSEKDKALMQ-QKMEFMEVQLDE----YKKQIEENKKSHEAIMKA 798

Query: 1046 YESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMN 1105
            +E+   + T K++  +    R  +   D K    E + + +    Q+ +L E     E+ 
Sbjct: 799  FENSSNESTYKIDAAKMNDLR-EQHKRDLKNIENEYESVKKRLQQQVDQLNERNSELELK 857

Query: 1106 IPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLN 1165
            +    G +I+  IE + +     +               +++ + +++   L  Q   + 
Sbjct: 858  VKFETGDLINE-IENLKEQLQTSE---------------EQKNKLLEQNKTLDGQKLSIL 901

Query: 1166 TELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSIS 1225
             E +  Y K  +++ L   +   D     ++NQ ++K E+  T+  N      E      
Sbjct: 902  KEQELRYQK--KIKQLEQAMDEADTKTAREVNQAQAKAEESLTQLKNFYEIERE------ 953

Query: 1226 SAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNK 1285
              +++R  E  E   +     + +F    H+LR     +E + E L D ++   Q+ TN 
Sbjct: 954  -RLERRICEEKEKSDKKFQAAQEEFY---HKLRETEQNYEEEIETLKDDLRDQVQQYTNT 1009

Query: 1286 IVTMEQVTSL-QNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXX 1344
            I   +   +L Q  ++  E+H++ ++E+   + N      + +E +  +F          
Sbjct: 1010 IQQYDHEIALKQQTIEIFEKHIKEIKEQLISLQNNNN---TTLEQQMNSFTTERKSLISK 1066

Query: 1345 XXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLE 1404
                   L    + +  +Q++  L  NE+  + ++               ++  E    E
Sbjct: 1067 NDVLSSQLNNLQKEHMALQQKKDLLENEKTRKEQQFEQSRKEWQEEKRELIDRLE----E 1122

Query: 1405 LTHQLELKDSEIYQKTHEY--TITLTQRNDEF--------------------ENVRQQLV 1442
               +L+  + E  +K  EY     LTQ+ +EF                    E ++QQ  
Sbjct: 1123 TKQRLQKMNDEFLEKKIEYGRETALTQQQNEFLQKKIEDLQKQIDTQQSRFDEKIKQQKN 1182

Query: 1443 EY----EKRIEDLTYEKES-ELAILRLKMHENANHYETMQKESEIERVKLIEELNVKITE 1497
            EY    E+++E    EK + E    ++K     N Y+  ++ S +ER K I      +TE
Sbjct: 1183 EYSVELEQKLERAQEEKTAIETKYEKIKKQLKENEYQYNKQASTLEREKAI------LTE 1236

Query: 1498 SV-SLNKQVAELNKALEEEVAKTNEMQTALENQ-EIEIVTLNDEITNLQNM-VRASSSKI 1554
             +  L+ +  EL   +++E A   + QTAL  Q   E  +L  E+   +   ++    K 
Sbjct: 1237 KLGQLDSRKNELESKIKDESASVAQYQTALREQIAAEKKSLQQELEKYKQFNLQLEQEKS 1296

Query: 1555 QKHVSFASDTK--QGRD---EQLDNTMNKELLDAVPRAELDL 1591
            + H S+  D    +G+    EQ      ++L+DA+ + E+ L
Sbjct: 1297 EIHTSYERDKALWEGKFQFLEQQKEQAKQDLMDALKKFEMTL 1338



 Score = 87.8 bits (208), Expect = 2e-15
 Identities = 181/976 (18%), Positives = 404/976 (41%), Gaps = 82/976 (8%)

Query: 145  THLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXX 204
            T   N+  EK+ AL  L+ K+   E  + ++  K  E D   E KN              
Sbjct: 589  TLFGNSEFEKERAL--LEQKITFFEKLVNEMNAK--EVDYQNEIKNLRKEHSLQSKDQQT 644

Query: 205  XXXXXXXEDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLE----EANKLL 260
                   +  +Q+++ +QE    ME E  +++     D +  + +  SL     E N+ +
Sbjct: 645  KSDQTVRQ-LQQKLSDLQEKLNEMENELIEKESNFENDFKKFEHKERSLTKQNLEQNEQI 703

Query: 261  EAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTE-IEEKGSLEIA 319
            +A   EI  E+ +  ++++Q                 Q +E   + K + +++  S    
Sbjct: 704  QALTREIR-EYKRNEEQMQQMLKSDANNQVNELLEKVQGLEDLIKTKDDQLKQAKSHSEK 762

Query: 320  NMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTA 379
            +   + +K+E +E    Q+ +  K++E    +     KA  + S + +  I      +  
Sbjct: 763  DKALMQQKMEFME---VQLDEYKKQIEENKKSHEAIMKAFENSSNESTYKIDAAKMNDLR 819

Query: 380  SKMKSPWSQLSSE------TLNQDTDKKINKNEIAKLEMVIQSLNKDLVDK-EYVISEKD 432
             + K     + +E       L Q  D+   +N  ++LE+ ++    DL+++ E +  +  
Sbjct: 820  EQHKRDLKNIENEYESVKKRLQQQVDQLNERN--SELELKVKFETGDLINEIENLKEQLQ 877

Query: 433  TXXXXXXXXXXGKDTLIAQ-LQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELND 491
            T             TL  Q L +  +Q +     I       D  +    +E  + +   
Sbjct: 878  TSEEQKNKLLEQNKTLDGQKLSILKEQELRYQKKIKQLEQAMDEADTKTAREVNQAQAKA 937

Query: 492  EIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKV- 550
            E     +K+  E  +   E+  ++ +E + ++K     +     KL++ ++  +   +  
Sbjct: 938  EESLTQLKNFYEIERERLER--RICEEKEKSDKKFQAAQEEFYHKLRETEQNYEEEIETL 995

Query: 551  -SDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEME-NL 608
              D   ++ + T  +     ++A  ++     + H+ +     +   +     +E + N 
Sbjct: 996  KDDLRDQVQQYTNTIQQYDHEIALKQQTIEIFEKHIKEIKEQLISLQNNNNTTLEQQMNS 1055

Query: 609  AETRLKAI----SLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHL 664
              T  K++     +L SQ  +L +E   LQQK D +E++     Q Q +Q   E +    
Sbjct: 1056 FTTERKSLISKNDVLSSQLNNLQKEHMALQQKKDLLENEKTRKEQ-QFEQSRKEWQE-EK 1113

Query: 665  EEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMD----- 719
             E ID L  +K+ L  + +   L+K+  YG    L   + + + K    +Q+ +D     
Sbjct: 1114 RELIDRLEETKQRLQKMNDEF-LEKKIEYGRETALTQQQNEFLQKKIEDLQKQIDTQQSR 1172

Query: 720  LTDKLEKMSAEKISELLAKINH--EEQSKIQTQFG-IDAKIQERDLYIENIESELSKYKS 776
              +K+++   E   EL  K+    EE++ I+T++  I  +++E +       S L + K+
Sbjct: 1173 FDEKIKQQKNEYSVELEQKLERAQEEKTAIETKYEKIKKQLKENEYQYNKQASTLEREKA 1232

Query: 777  RICRLEESIAVMEDRRYSLERKA-DQLGSY-----------------LQEKQKAYSEYTI 818
                L E +  ++ R+  LE K  D+  S                  LQ++ + Y ++ +
Sbjct: 1233 I---LTEKLGQLDSRKNELESKIKDESASVAQYQTALREQIAAEKKSLQQELEKYKQFNL 1289

Query: 819  QEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQ-HYN 877
            Q ++  + +    + D+ + +   +   + KE  K++  L++  +  +++L  +Q+   N
Sbjct: 1290 QLEQEKSEIHTSYERDKALWEGKFQFLEQQKEQAKQD--LMDALKKFEMTLMHLQRARSN 1347

Query: 878  ALVEKANR-TDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQI 936
               E+ N   +L  S   KYQ+Q+ +     +RI  +++  I + +KE++    +     
Sbjct: 1348 EKDEQENNLNELLLSVERKYQSQIEEANQTHQRIVQDYEDKIRRLQKEVKTHRDKILIDQ 1407

Query: 937  ESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQ 996
               I ++ +  +K+ + ++   +L+   QE +N  ++ +  + E  KM    +++  +  
Sbjct: 1408 HGKIGNQLLSEKKFAEMLDNEKRLQ---QEIENIKQDRDYKIFEYQKM----LEQERENL 1460

Query: 997  QTQSPDYTEQYINEINKLNALLKQKDEEIIALN---QKINNAQV---SYMSMVSDYESKL 1050
            + +  +   +Y    NK + L+ + ++E    N     +NN +      +  +SD + +L
Sbjct: 1461 KAKIVELETKYKEVENKRSTLIFEFEKERAKWNLDRDHLNNIKTELSDQLEKLSDKKEQL 1520

Query: 1051 AQFTTKLENMEEEMQR 1066
             +   KL+N +   +R
Sbjct: 1521 LRENEKLKNEQRATRR 1536


>UniRef50_A0CY92 Cluster: Chromosome undetermined scaffold_31, whole
            genome shotgun sequence; n=3; Paramecium tetraurelia|Rep:
            Chromosome undetermined scaffold_31, whole genome shotgun
            sequence - Paramecium tetraurelia
          Length = 980

 Score =  122 bits (294), Expect = 8e-26
 Identities = 187/896 (20%), Positives = 415/896 (46%), Gaps = 93/896 (10%)

Query: 481  VQEQLKQELNDEIKDVNV-KDLIEK----LKSAEEQITQLN------DEIDAANKNMIKV 529
            +QE+LKQ  + ++K++ + K  IEK    L+   +QI Q        ++I+ A K  +K 
Sbjct: 38   LQEELKQNESQKLKEIEIIKVEIEKGLHHLQEKNQQIEQQTVTIQELEQINHALKEELKQ 97

Query: 530  KSNHKLKLKQMQKT-IDN-FSKVSDSNKEIVRLT------EELHHL---------SQKVA 572
            K   KLK  ++ K  I+     + + N++I + T      E+++H          SQK+ 
Sbjct: 98   KEEQKLKEIEIIKVEIEKGLHHLQEKNQQIEQQTATIQELEQINHALQEELKENESQKLK 157

Query: 573  ELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAET----------RLKAISLLESQ 622
            E+E  K   +     +   R+ +S+  +++ + +N  ++          + K  + +E  
Sbjct: 158  EIEINKVENRKRSSSFGKKRINKSNSKQQLFKNQNQKKSCTQRRNQSRKKNKNQNEIEII 217

Query: 623  KFDLVQELHILQQKYDEVEDKLADISQL-QSDQVCSEIKSVHLEEQIDALSASKKELALV 681
            K ++ + LH LQ+K  ++E + A I +L Q +    E      E+++  +   K E+   
Sbjct: 218  KVEIEKGLHHLQEKNQQIEQQSATIQELEQKNHALKEELKQKEEQKLKEIEIIKVEIEKG 277

Query: 682  IENLKLDKEQL---YGTIKDLENDKEDIMNKL-QNYIQENMDLTDKLEKMSAEK-ISELL 736
            + +L+   +Q+     TI++LE     +  +L QN  Q+  ++  ++ K+  EK +  L 
Sbjct: 278  LHHLQEKNQQIEQQTATIQELEQKNHALQEELKQNESQKLKEI--EIIKVEIEKGLHHLQ 335

Query: 737  AKINHEEQSKIQTQFGIDAKIQERDLY-IENIESELSKYKSRICRLEESIAVMEDRRYSL 795
             K    EQ   Q    +  ++++ +   ++ IE    +    +  L+E    +E +  ++
Sbjct: 336  EKNQQIEQQTKQKNHALQEELKQNESQKLKEIEIIKVEIGQGLHHLQEKNQQIEQQSATI 395

Query: 796  ERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKN 855
            + + +Q    LQE+ K   E  ++E E +N++         +EK L  ++ +N+++++++
Sbjct: 396  Q-ELEQKNHALQEELKQKEEQKLKEIE-INKVE--------IEKGLHHLQEKNQQIEQQS 445

Query: 856  QILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQT-QLRDLESNLKRITHEH 914
              + E  Q    +L   ++     +EK       +++  + Q+  +++LE     +  E 
Sbjct: 446  ATIQELEQKKSCTLRRTKKLIKVEIEKGLHHLQEKNQQIEQQSATIKELEQKNHALQEEL 505

Query: 915  QTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENL 974
            +    QK KEIE +++E   +  + I        + +K+    TQ     +E K N E+ 
Sbjct: 506  KQKEEQKLKEIEIIKVEIGQESINRIVISNYSRIRIKKSC--TTQ-----EELKEN-ESQ 557

Query: 975  NMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINN 1034
             +   E+ K+ +E    H+Q++  Q    T   I E+ ++N  LK++ +E    +QK+  
Sbjct: 558  KLKEIEIIKVEIEKGLHHLQEKNQQIEQQTAT-IQELEQINHALKEELKE--NESQKLKE 614

Query: 1035 AQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQ-IK 1093
             ++         + ++ Q    L+   +++++ S  + + +Q N  L+  ++++++Q +K
Sbjct: 615  IEI--------IKVEIGQGLHHLQEKNQQIEQQSATIQELEQKNHALKEELKQKEEQKLK 666

Query: 1094 ELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQE 1153
            E++  K+  E  +       +    + +      +             LK Q+EE+ ++E
Sbjct: 667  EIEIIKVEIEKGLHH-----LQEKNQQIEQQTVTIQELEQKNHALKEELK-QKEEQKLKE 720

Query: 1154 RSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKS-KLEQLNTENDN 1212
              +++ Q  +    LQE   +I Q      EL   +   QE++ + +S KL+++      
Sbjct: 721  IEIIKVQIGQGLHHLQEKNQQIEQQSATIQELEQKNHALQEELKENESQKLKEIEIIKVE 780

Query: 1213 LLSTVAELRSSISSAVDQRGFEIAELWKQHLAQREADFQKTEHELRVQLSAFESKYEQLL 1272
            +   V  L+   +  ++Q+   I EL +++ A +E   QK E +L+ ++   + + E+ L
Sbjct: 781  IGQGVHHLQEK-NQQIEQQSAIIKELEQKNHALQEELKQKEEQKLK-EIEIIKVEIEKGL 838

Query: 1273 DSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIEILRSEIE 1328
              +Q   Q+   + VT++++    + LQ++      L++  +  + +IEI++ EIE
Sbjct: 839  HHLQEKNQQIEQQSVTIQELEQKNHALQEE------LKQNESQKLKEIEIIKVEIE 888



 Score =  120 bits (288), Expect = 4e-25
 Identities = 202/1015 (19%), Positives = 454/1015 (44%), Gaps = 94/1015 (9%)

Query: 595  ESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQ 654
            +S+  K     E L +   + +  +E  K ++ + LH LQ+K  ++E +   I +L  +Q
Sbjct: 29   KSNKQKNHALQEELKQNESQKLKEIEIIKVEIEKGLHHLQEKNQQIEQQTVTIQEL--EQ 86

Query: 655  VCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYI 714
            +   +K        + L   +++    IE +K++ E+    +++     E     +Q   
Sbjct: 87   INHALK--------EELKQKEEQKLKEIEIIKVEIEKGLHHLQEKNQQIEQQTATIQELE 138

Query: 715  QENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFG---IDAKIQERDLY-IENIESE 770
            Q N  L ++L++  ++K+ E+  +IN  E  K  + FG   I+    ++ L+  +N +  
Sbjct: 139  QINHALQEELKENESQKLKEI--EINKVENRKRSSSFGKKRINKSNSKQQLFKNQNQKKS 196

Query: 771  LSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEY--TIQEDELVNRLA 828
             ++ +++  +  ++   +E  +  +E+       +LQEK +   +   TIQE E  N  A
Sbjct: 197  CTQRRNQSRKKNKNQNEIEIIKVEIEKGL----HHLQEKNQQIEQQSATIQELEQKNH-A 251

Query: 829  VLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQ---ISLSDMQQHYNALVEKANR 885
            +  +  +  E++L EIE    E++K    L E+NQ ++    ++ +++Q  +AL E+  +
Sbjct: 252  LKEELKQKEEQKLKEIEIIKVEIEKGLHHLQEKNQQIEQQTATIQELEQKNHALQEELKQ 311

Query: 886  TDLAESESTKYQTQLR-DLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKK 944
                ES+  K    ++ ++E  L  +  ++Q +  Q K++   L+ E        +++ +
Sbjct: 312  N---ESQKLKEIEIIKVEIEKGLHHLQEKNQQIEQQTKQKNHALQEELKQNESQKLKEIE 368

Query: 945  VLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYT 1004
            ++  +  + + +       LQE    IE  +  ++EL + N  L ++  QK++ +  +  
Sbjct: 369  IIKVEIGQGLHH-------LQEKNQQIEQQSATIQELEQKNHALQEELKQKEEQKLKEIE 421

Query: 1005 EQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKL-AQFTTKLENMEEE 1063
               + EI K    L++K+++I   +  I   +      +   +  +  +    L +++E+
Sbjct: 422  INKV-EIEKGLHHLQEKNQQIEQQSATIQELEQKKSCTLRRTKKLIKVEIEKGLHHLQEK 480

Query: 1064 MQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSD 1123
             Q++ +Q    K+  ++   L     +++K+ +E KL  E+ I K E  I   +I  +  
Sbjct: 481  NQQIEQQSATIKELEQKNHAL----QEELKQKEEQKLK-EIEIIKVE--IGQESINRIV- 532

Query: 1124 DANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNT 1183
              +N                 + E + ++E  +++ +  K    LQE   +I Q      
Sbjct: 533  -ISNYSRIRIKKSCTTQEELKENESQKLKEIEIIKVEIEKGLHHLQEKNQQIEQQTATIQ 591

Query: 1184 ELTGHDVVNQEQINQLKS-KLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQH 1242
            EL   +   +E++ + +S KL+++      +   +  L+   +  ++Q+   I EL +++
Sbjct: 592  ELEQINHALKEELKENESQKLKEIEIIKVEIGQGLHHLQEK-NQQIEQQSATIQELEQKN 650

Query: 1243 LAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDK 1302
             A +E   QK E +L+ ++   + + E+ L  +Q   Q+   + VT++++    + L  K
Sbjct: 651  HALKEELKQKEEQKLK-EIEIIKVEIEKGLHHLQEKNQQIEQQTVTIQELEQKNHAL--K 707

Query: 1303 EEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQM 1362
            EE    L++K    + +IEI++ +I                        L+ +NQ  +Q 
Sbjct: 708  EE----LKQKEEQKLKEIEIIKVQI------------------GQGLHHLQEKNQQIEQ- 744

Query: 1363 QEQSILNINEEN----AQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDS---E 1415
            Q  +I  + ++N     +LK++              +      + E   Q+E + +   E
Sbjct: 745  QSATIQELEQKNHALQEELKENESQKLKEIEIIKVEIGQGVHHLQEKNQQIEQQSAIIKE 804

Query: 1416 IYQKTHEYTITLTQRNDE-FENVRQQLVEYEKRIEDLTYEKES-ELAILRLKMHENANH- 1472
            + QK H     L Q+ ++  + +    VE EK +  L  + +  E   + ++  E  NH 
Sbjct: 805  LEQKNHALQEELKQKEEQKLKEIEIIKVEIEKGLHHLQEKNQQIEQQSVTIQELEQKNHA 864

Query: 1473 YETMQKESEIERVKLIEELNVKITESV----SLNKQVAELNKALEEEVAKTNEMQTAL-- 1526
             +   K++E +++K IE + V+I + +      N+Q+ +    ++E   K + +Q  L  
Sbjct: 865  LQEELKQNESQKLKEIEIIKVEIEKGLHHLQEKNQQIEQQTVTIQELEQKNHALQEELKQ 924

Query: 1527 -ENQEI-EIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLDNTMNKE 1579
             E+Q++ EI  +  EI    + ++  + +I++  +   + +Q      +   NK+
Sbjct: 925  NESQKLKEIEIIKVEIGQGLHHLQEKNQQIEQQSATIQELEQKNHALQEELKNKQ 979



 Score =  109 bits (263), Expect = 5e-22
 Identities = 162/787 (20%), Positives = 347/787 (44%), Gaps = 48/787 (6%)

Query: 477  EIAKVQEQLKQELNDEIKD--VNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKV---KS 531
            EI K    L QE N +I+     +++L +K  + +E++ Q  +E       +IKV   K 
Sbjct: 220  EIEKGLHHL-QEKNQQIEQQSATIQELEQKNHALKEELKQ-KEEQKLKEIEIIKVEIEKG 277

Query: 532  NHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEEL-HHLSQKVAELEEEKGNLQ--LHLVDY 588
             H L+ K  Q+     + + +  ++   L EEL  + SQK+ E+E  K  ++  LH +  
Sbjct: 278  LHHLQEKN-QQIEQQTATIQELEQKNHALQEELKQNESQKLKEIEIIKVEIEKGLHHLQE 336

Query: 589  DSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADIS 648
             + ++ +    K     E L +   + +  +E  K ++ Q LH LQ+K  ++E + A I 
Sbjct: 337  KNQQIEQQTKQKNHALQEELKQNESQKLKEIEIIKVEIGQGLHHLQEKNQQIEQQSATIQ 396

Query: 649  QL-QSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQL---YGTIKDLENDKE 704
            +L Q +    E      E+++  +  +K E+   + +L+   +Q+     TI++LE  K 
Sbjct: 397  ELEQKNHALQEELKQKEEQKLKEIEINKVEIEKGLHHLQEKNQQIEQQSATIQELEQKKS 456

Query: 705  DIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYI 764
              + + +  I+  ++      +   ++I +  A I   EQ     Q  +  K +++   I
Sbjct: 457  CTLRRTKKLIKVEIEKGLHHLQEKNQQIEQQSATIKELEQKNHALQEELKQKEEQKLKEI 516

Query: 765  ENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELV 824
            E I+ E+   +  I R    I +    R  +++         + + +   E  I + E+ 
Sbjct: 517  EIIKVEIG--QESINR----IVISNYSRIRIKKSCTTQEELKENESQKLKEIEIIKVEIE 570

Query: 825  NRLAVLMDHDRVVEKQLLEIEHENKELQKKNQILLEE-NQNLQISLSDMQQHYNALVEKA 883
              L  L + ++ +E+Q   I+    EL++ N  L EE  +N    L +++     + +  
Sbjct: 571  KGLHHLQEKNQQIEQQTATIQ----ELEQINHALKEELKENESQKLKEIEIIKVEIGQGL 626

Query: 884  NRTDLAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDK 943
            +       +  +    +++LE     +  E +    QK KEIE +++E    IE  +   
Sbjct: 627  HHLQEKNQQIEQQSATIQELEQKNHALKEELKQKEEQKLKEIEIIKVE----IEKGLHHL 682

Query: 944  KVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDY 1003
            +  N++ E+    + +LE +    K  ++      EE     +E+I    + Q  Q   +
Sbjct: 683  QEKNQQIEQQTVTIQELEQKNHALKEELK----QKEEQKLKEIEII----KVQIGQGLHH 734

Query: 1004 TEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEE 1063
             ++   +I + +A +++ +++  AL +++   +   +  +   + ++ Q    L+   ++
Sbjct: 735  LQEKNQQIEQQSATIQELEQKNHALQEELKENESQKLKEIEIIKVEIGQGVHHLQEKNQQ 794

Query: 1064 MQRVSKQLLDSKQHNEELQILVREQDDQ-IKELKETKLTFEMNIPKTEGMIISSTIEPMS 1122
            +++ S  + + +Q N  LQ  ++++++Q +KE++  K+  E  +   +    +  IE  S
Sbjct: 795  IEQQSAIIKELEQKNHALQEELKQKEEQKLKEIEIIKVEIEKGLHHLQEK--NQQIEQQS 852

Query: 1123 DDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLN 1182
                 ++            LK Q E + ++E  +++ +  K    LQE   +I Q     
Sbjct: 853  VTIQELE---QKNHALQEELK-QNESQKLKEIEIIKVEIEKGLHHLQEKNQQIEQQTVTI 908

Query: 1183 TELTGHDVVNQEQINQLKS-KLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAEL-WK 1240
             EL   +   QE++ Q +S KL+++      +   +  L+   +  ++Q+   I EL  K
Sbjct: 909  QELEQKNHALQEELKQNESQKLKEIEIIKVEIGQGLHHLQEK-NQQIEQQSATIQELEQK 967

Query: 1241 QHLAQRE 1247
             H  Q E
Sbjct: 968  NHALQEE 974



 Score =   99 bits (238), Expect = 5e-19
 Identities = 151/695 (21%), Positives = 307/695 (44%), Gaps = 90/695 (12%)

Query: 216 QQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISS----LEEANKLLEAARFEISLEH 271
           +Q TK + +  A++ E K  + + LK+IE   V I      L+E N+ +E        + 
Sbjct: 342 EQQTKQKNH--ALQEELKQNESQKLKEIEIIKVEIGQGLHHLQEKNQQIE--------QQ 391

Query: 272 SKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELL 331
           S   QELEQ                  +++   ++K E + K  +EI N  E+ K +  L
Sbjct: 392 SATIQELEQK---------------NHALQEELKQKEEQKLK-EIEI-NKVEIEKGLHHL 434

Query: 332 EHLNCQIRQ---TNKELENKLA-TMGTESKAVSSPSKKGSPLISRKSGR----NTASKMK 383
           +  N QI Q   T +ELE K + T+    K +    +KG   +  K+ +    +   K  
Sbjct: 435 QEKNQQIEQQSATIQELEQKKSCTLRRTKKLIKVEIEKGLHHLQEKNQQIEQQSATIKEL 494

Query: 384 SPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXX 443
              +    E L Q  ++K+ + EI K+E+  +S+N+ ++     I  K +          
Sbjct: 495 EQKNHALQEELKQKEEQKLKEIEIIKVEIGQESINRIVISNYSRIRIKKSCTTQEELKEN 554

Query: 444 G----KDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQEL--NDEIKDVN 497
                K+  I ++++E   H        +   T  + E+ ++   LK+EL  N+  K   
Sbjct: 555 ESQKLKEIEIIKVEIEKGLHHLQEKNQQIEQQTATIQELEQINHALKEELKENESQKLKE 614

Query: 498 VKDLIEKLKSAEEQITQLNDEIDAANKNMIKV-KSNHKLKLKQMQKTIDNFSKVSDSNKE 556
           ++ +  ++      + + N +I+  +  + ++ + NH LK +  QK      ++     E
Sbjct: 615 IEIIKVEIGQGLHHLQEKNQQIEQQSATIQELEQKNHALKEELKQKEEQKLKEIEIIKVE 674

Query: 557 IVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAI 616
           I    + LHHL +K  ++E++   +Q           +E   +    E++   E +LK I
Sbjct: 675 I---EKGLHHLQEKNQQIEQQTVTIQ----------ELEQKNHALKEELKQKEEQKLKEI 721

Query: 617 SLLESQKFDLVQELHILQQKYDEVEDKLADISQL-QSDQVCSEIKSVHLEEQIDALSASK 675
            ++   K  + Q LH LQ+K  ++E + A I +L Q +    E    +  +++  +   K
Sbjct: 722 EII---KVQIGQGLHHLQEKNQQIEQQSATIQELEQKNHALQEELKENESQKLKEIEIIK 778

Query: 676 KELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISEL 735
            E+   + +L+   +Q+          +  I+ +L+   Q+N  L ++L++   +K+ E+
Sbjct: 779 VEIGQGVHHLQEKNQQI--------EQQSAIIKELE---QKNHALQEELKQKEEQKLKEI 827

Query: 736 LAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIAVMEDRRYS- 794
                  E  K++ + G+   +QE++  IE     + + + +   L+E +   E ++   
Sbjct: 828 -------EIIKVEIEKGLH-HLQEKNQQIEQQSVTIQELEQKNHALQEELKQNESQKLKE 879

Query: 795 ---LERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQ-LLEIEHENKE 850
              ++ + ++   +LQEK +   + T+   EL  +   L +  +  E Q L EIE    E
Sbjct: 880 IEIIKVEIEKGLHHLQEKNQQIEQQTVTIQELEQKNHALQEELKQNESQKLKEIEIIKVE 939

Query: 851 LQKKNQILLEENQNLQ---ISLSDMQQHYNALVEK 882
           + +    L E+NQ ++    ++ +++Q  +AL E+
Sbjct: 940 IGQGLHHLQEKNQQIEQQSATIQELEQKNHALQEE 974


>UniRef50_A0CY31 Cluster: Chromosome undetermined scaffold_30, whole
            genome shotgun sequence; n=2; Paramecium tetraurelia|Rep:
            Chromosome undetermined scaffold_30, whole genome shotgun
            sequence - Paramecium tetraurelia
          Length = 1036

 Score =  122 bits (294), Expect = 8e-26
 Identities = 215/1020 (21%), Positives = 445/1020 (43%), Gaps = 106/1020 (10%)

Query: 598  VYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCS 657
            VYK+++ ME+  + R++    LE+Q +++ ++  + ++KY E+E  L D  +  ++    
Sbjct: 12   VYKQVV-MEHKEDERVEQ---LEAQIYNMEKDHSMWRKKYFELES-LYDKCRYAAE---- 62

Query: 658  EIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQEN 717
              KSV LE++I+ L     +++ ++     + E++   +  LEN+  ++     N ++  
Sbjct: 63   --KSVQLEDRINLLRQDNSQISALLREKATECEKMRVRLTQLENENFEL-----NTVRLQ 115

Query: 718  MDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSR 777
            +   + L +   + I ELL K N E  +++    G +  I++    + ++  +L  +K  
Sbjct: 116  VTKFNDLLQQKTQDI-ELLRKKNSEIYARVIELEGNELVIRDYKSQVNSLTKDLDVWKKL 174

Query: 778  I-CRLEESIAVMEDRRY---------SLERKADQLGSYLQEKQKAYSEYTIQEDELVNRL 827
               + +E + ++E  R          S++    Q+   ++ +    SE T    +L + L
Sbjct: 175  YEDQQQERVKLLEIIRQFEQNNPLSGSIKSSQQQVSEVIERRVVTTSETTNNTQQLQSSL 234

Query: 828  AVLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTD 887
                     +E +L   E +  +L+++ +  ++ N  L+I ++  +      ++  N   
Sbjct: 235  LQNQATISDLEDRLGFSEKQYDKLKQELEARIKMNNELKIKITQQECE----LKNINYLK 290

Query: 888  LAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQ--IESAIRDKKV 945
            L   ++ K + QL   +  L +   ++ T + + +   + L   +N +  ++   +++  
Sbjct: 291  L---DNQKLKDQLDQTKRELDQFRKQYYTTLSKLQIAEQQLNELYNLENRLQLLQQERDT 347

Query: 946  LNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTE 1005
            LN+  ++  E + QL+ ++    + IE L +N +  N    E+I                
Sbjct: 348  LNKSLKQKNEDIGQLQDKVSSLLSQIEQLRLNDQARNAAENEVI---------------- 391

Query: 1006 QYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQ 1065
            Q   E++KL A LKQK++ I  L+ +IN+ Q    +  SD++   A+  + L++  + + 
Sbjct: 392  QLKTELSKLQANLKQKEQTISDLHGRINDLQKQLTNSQSDFKRLQAKDYSGLQDQAKLVN 451

Query: 1066 RVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDA 1125
             + ++LL   Q N + Q        Q   L+    +   +I +   ++ + T E +SD  
Sbjct: 452  ELQQKLLQLSQDNSKFQ-------SQAFNLESKNNSQVQDIQRLNSLLSTKTQE-LSD-- 501

Query: 1126 NNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTEL 1185
             N              LK Q   + I E    + ++  L  +LQ    +IIQ   LNT+L
Sbjct: 502  ANKKIYDLENDKTIPDLKFQ-NSQLIAELREQETENKGLQEKLQILENQIIQ---LNTKL 557

Query: 1186 TGHDVVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQRGFEIAELWKQHLAQ 1245
            T  +      +N+ K+K++QL      L S + +L S +   VDQ      ++ +Q    
Sbjct: 558  TTAEAQANCNLNE-KNKVDQL------LTSYLLQL-SQLEKEVDQLRVIAQQVAQQSAIN 609

Query: 1246 READFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEH 1305
            ++   ++    L+ QL    S++ +L    +    + +     + Q++ L NK+Q  +E 
Sbjct: 610  KQQ--EQLVQALQKQLKDQTSQFNELSKENEKLYVDNSQLSTRISQLSELPNKIQILDEG 667

Query: 1306 LRNLQEKYADVINQIEILRSEIEDE---KVAFXXXXXXXXXXXXXXXXDLRTENQSYKQM 1362
            L+ LQ+ Y + +   E L  ++ D    K                    L +     +Q+
Sbjct: 668  LQKLQQDYNNELQANETLNKQLNDALKVKNDLENKIAMLSTEVERFQYKLNSRQNEAEQL 727

Query: 1363 QEQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVL-ELTHQLELKDSEIYQKTH 1421
            ++Q I+++  + AQLK+              ++   E +++ E    LE        +T 
Sbjct: 728  KKQ-IVDLETQIAQLKQ----LESENQVLADKIAHLEQQIINEANKNLEHLLRVSQDETK 782

Query: 1422 EYTI---TLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQ- 1477
             Y +    L Q+ D+ E   +Q  E  K++E    + +S    L  +  + A     +  
Sbjct: 783  SYVLDNNKLKQQLDQREQENKQKDESYKQLEQKYQQLQSSNKNLEAQNTQIAELQNVIAG 842

Query: 1478 KESEIERVK-LIEELNVK----ITESVSLN-------KQVAELNKALEEEVAKTNEMQT- 1524
            +E++I++ + LIEEL  K    + ES  L+        Q+A+L   +E+   + N  Q  
Sbjct: 843  QENDIQKFQDLIEELRDKNNDLVAESQKLSIELTQQQVQIADLKNQIEKLNTQVNNNQNY 902

Query: 1525 --ALENQEIEIVTLNDEITNLQNMVRASSSKIQK-HVSF-ASDTKQGRDEQLDNTMNKEL 1580
               +E  + +I  L +E   L+N V   SS+I++  V + A   K    E+    + KEL
Sbjct: 903  DQLIEELKKKIEKLQEEKYQLENKVALLSSEIERMRVKYDAQGNKLNISEEQKQGLTKEL 962



 Score =  109 bits (263), Expect = 5e-22
 Identities = 183/965 (18%), Positives = 418/965 (43%), Gaps = 85/965 (8%)

Query: 504  KLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEE 563
            +L +   Q+T+ ND +    +++  ++  +     ++ +   N   + D   ++  LT++
Sbjct: 108  ELNTVRLQVTKFNDLLQQKTQDIELLRKKNSEIYARVIELEGNELVIRDYKSQVNSLTKD 167

Query: 564  LHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQK 623
            L    +   + ++E+  L   +  ++    +   +     ++  + E R+   S   +  
Sbjct: 168  LDVWKKLYEDQQQERVKLLEIIRQFEQNNPLSGSIKSSQQQVSEVIERRVVTTSETTNNT 227

Query: 624  FDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKS-VHLEEQIDALSASKKELALV- 681
              L   L   Q    ++ED+L   S+ Q D++  E+++ + +  ++  +  +++E  L  
Sbjct: 228  QQLQSSLLQNQATISDLEDRLG-FSEKQYDKLKQELEARIKMNNEL-KIKITQQECELKN 285

Query: 682  IENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINH 741
            I  LKLD ++       L++  +    +L  + ++      KL+ ++ ++++EL   + +
Sbjct: 286  INYLKLDNQK-------LKDQLDQTKRELDQFRKQYYTTLSKLQ-IAEQQLNELY-NLEN 336

Query: 742  EEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRL---EESIAVMEDRRYSLERK 798
              Q   Q +  ++  +++++  I  ++ ++S   S+I +L   +++    E+    L+ +
Sbjct: 337  RLQLLQQERDTLNKSLKQKNEDIGQLQDKVSSLLSQIEQLRLNDQARNAAENEVIQLKTE 396

Query: 799  ADQLGSYLQEKQKAYSEYTIQEDELVNRLA-VLMDHDRVVEKQLLEIEHENK---ELQKK 854
              +L + L++K++  S+   + ++L  +L     D  R+  K    ++ + K   ELQ+K
Sbjct: 397  LSKLQANLKQKEQTISDLHGRINDLQKQLTNSQSDFKRLQAKDYSGLQDQAKLVNELQQK 456

Query: 855  NQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEH 914
               L ++N   Q    +++   N+ V+   R  L    STK Q +L D    +  + ++ 
Sbjct: 457  LLQLSQDNSKFQSQAFNLESKNNSQVQDIQR--LNSLLSTKTQ-ELSDANKKIYDLEND- 512

Query: 915  QTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIE-N 973
                    K I DL+ + N+Q+ + +R+++  N+  ++ ++ +     QL       E  
Sbjct: 513  --------KTIPDLKFQ-NSQLIAELREQETENKGLQEKLQILENQIIQLNTKLTTAEAQ 563

Query: 974  LNMNVEELNKMNLELIDKHVQKQQTQSP-DYTEQYINEINKLNALLKQKDEEIIALNQKI 1032
             N N+ E NK++  L    +Q  Q +   D       ++ + +A+ KQ+++ + AL +++
Sbjct: 564  ANCNLNEKNKVDQLLTSYLLQLSQLEKEVDQLRVIAQQVAQQSAINKQQEQLVQALQKQL 623

Query: 1033 NNAQVSYMSMVSDYESKL----AQFTTKLENMEEEMQRVSKQLLD------SKQHNEELQ 1082
             + Q S  + +S    KL    +Q +T++  + E   ++  Q+LD       + +N ELQ
Sbjct: 624  KD-QTSQFNELSKENEKLYVDNSQLSTRISQLSELPNKI--QILDEGLQKLQQDYNNELQ 680

Query: 1083 ILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXL 1142
                  + Q+ +  + K   E  I      ++S+ +E      N+              L
Sbjct: 681  -ANETLNKQLNDALKVKNDLENKI-----AMLSTEVERFQYKLNSRQNEAEQLKKQIVDL 734

Query: 1143 KVQ--EEEEFIQERSVLQEQSAKLNTE-LQECYTKIIQLETLNTELTGHDVVNQEQINQL 1199
            + Q  + ++   E  VL ++ A L  + + E    +  L  ++ + T   V++  ++ Q 
Sbjct: 735  ETQIAQLKQLESENQVLADKIAHLEQQIINEANKNLEHLLRVSQDETKSYVLDNNKLKQQ 794

Query: 1200 KSKLEQLNTENDNLLSTVAELRSSISSA---VDQRGFEIAELWKQHLAQREADFQKTEHE 1256
              + EQ N + D     + +    + S+   ++ +  +IAEL +  +A +E D QK +  
Sbjct: 795  LDQREQENKQKDESYKQLEQKYQQLQSSNKNLEAQNTQIAEL-QNVIAGQENDIQKFQD- 852

Query: 1257 LRVQLSAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADV 1316
                +     K   L+   Q  + E T + V   Q+  L+N+++     + N  + Y  +
Sbjct: 853  ---LIEELRDKNNDLVAESQKLSIELTQQQV---QIADLKNQIEKLNTQVNN-NQNYDQL 905

Query: 1317 INQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQ 1376
            I +++    ++++EK                       E    K   + + LNI+EE  Q
Sbjct: 906  IEELKKKIEKLQEEKYQLENKVALLSS---------EIERMRVKYDAQGNKLNISEEQKQ 956

Query: 1377 LKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFEN 1436
                                +++ ++ +L  QL  K  E+ QK    ++TL    +E + 
Sbjct: 957  ------GLTKELEQVHKLFEESQDEIDKLQEQLS-KQKELEQKEQALSLTLVNAFNEIDA 1009

Query: 1437 VRQQL 1441
            +RQQL
Sbjct: 1010 LRQQL 1014



 Score =  101 bits (243), Expect = 1e-19
 Identities = 171/837 (20%), Positives = 377/837 (45%), Gaps = 69/837 (8%)

Query: 309  EIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLAT-MGTESKAVSSPSKKGS 367
            ++ E    E   + E+ ++ E    L+  I+ + +++   +   + T S+  ++  +  S
Sbjct: 173  KLYEDQQQERVKLLEIIRQFEQNNPLSGSIKSSQQQVSEVIERRVVTTSETTNNTQQLQS 232

Query: 368  PLISRKSGRNTASKMKSPWSQLSSETLNQDTDKKINKN-----EIAKLEMVIQSLNKDLV 422
             L+  ++  +     +  +S+   + L Q+ + +I  N     +I + E  ++++N   +
Sbjct: 233  SLLQNQATISDLED-RLGFSEKQYDKLKQELEARIKMNNELKIKITQQECELKNINYLKL 291

Query: 423  DKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQ 482
            D + +  + D              T +++LQ+  QQ  E  +L         +  + + +
Sbjct: 292  DNQKLKDQLDQTKRELDQFRKQYYTTLSKLQIAEQQLNELYNL------ENRLQLLQQER 345

Query: 483  EQLKQELNDEIKDVN-VKDLIEKLKSAEEQITQLNDEI-DAANKNMIKVKSN-HKLK--L 537
            + L + L  + +D+  ++D +  L S  EQ+ +LND+  +AA   +I++K+   KL+  L
Sbjct: 346  DTLNKSLKQKNEDIGQLQDKVSSLLSQIEQL-RLNDQARNAAENEVIQLKTELSKLQANL 404

Query: 538  KQMQKTI-DNFSKVSDSNKEIVRLTEELHHLSQK-VAELEEEK---GNLQLHLVDYDSGR 592
            KQ ++TI D   +++D  K++     +   L  K  + L+++      LQ  L+      
Sbjct: 405  KQKEQTISDLHGRINDLQKQLTNSQSDFKRLQAKDYSGLQDQAKLVNELQQKLLQLSQDN 464

Query: 593  MIESDVYKKMIEMENLAETRLKAISLLESQKFDLVQELHILQQK-YDEVEDKLADISQLQ 651
               S    +   +E+   ++++ I  L S      QEL    +K YD   DK     + Q
Sbjct: 465  ---SKFQSQAFNLESKNNSQVQDIQRLNSLLSTKTQELSDANKKIYDLENDKTIPDLKFQ 521

Query: 652  SDQVCSEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQ 711
            + Q+ +E++    E +         E  ++  N KL   +        E +K D +  L 
Sbjct: 522  NSQLIAELREQETENKGLQEKLQILENQIIQLNTKLTTAEAQANCNLNEKNKVDQL--LT 579

Query: 712  NYIQENMDLTDKLEKMS--AEKISELLAKINHEEQSKIQ----------TQFGIDAKIQE 759
            +Y+ +   L  +++++   A+++++  A IN +++  +Q          +QF   +K  E
Sbjct: 580  SYLLQLSQLEKEVDQLRVIAQQVAQQSA-INKQQEQLVQALQKQLKDQTSQFNELSKENE 638

Query: 760  RDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQ 819
            + LY++N  S+LS   S++  L   I ++++    L++  +      +   K  ++    
Sbjct: 639  K-LYVDN--SQLSTRISQLSELPNKIQILDEGLQKLQQDYNNELQANETLNKQLNDALKV 695

Query: 820  EDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKK-----NQI-----LLEENQNLQISL 869
            +++L N++A+L       + +L   ++E ++L+K+      QI     L  ENQ L   +
Sbjct: 696  KNDLENKIAMLSTEVERFQYKLNSRQNEAEQLKKQIVDLETQIAQLKQLESENQVLADKI 755

Query: 870  SDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESN-LKRITHEHQTLIVQKKKEIEDL 928
            + ++Q    ++ +AN+        ++ +T+   L++N LK+   + +    QK +  + L
Sbjct: 756  AHLEQQ---IINEANKNLEHLLRVSQDETKSYVLDNNKLKQQLDQREQENKQKDESYKQL 812

Query: 929  EIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNIENL----NMNVEELNKM 984
            E ++  Q++S+ ++ +  N +  +    +   E  +Q++++ IE L    N  V E  K+
Sbjct: 813  EQKYQ-QLQSSNKNLEAQNTQIAELQNVIAGQENDIQKFQDLIEELRDKNNDLVAESQKL 871

Query: 985  NLELIDKHVQ----KQQTQSPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYM 1040
            ++EL  + VQ    K Q +  +         ++L   LK+K E++     ++ N      
Sbjct: 872  SIELTQQQVQIADLKNQIEKLNTQVNNNQNYDQLIEELKKKIEKLQEEKYQLENKVALLS 931

Query: 1041 SMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKELKE 1097
            S +     K      KL   EE+ Q ++K+L    +  EE Q  + +  +Q+ + KE
Sbjct: 932  SEIERMRVKYDAQGNKLNISEEQKQGLTKELEQVHKLFEESQDEIDKLQEQLSKQKE 988


>UniRef50_A0C7H6 Cluster: Chromosome undetermined scaffold_155, whole
            genome shotgun sequence; n=1; Paramecium tetraurelia|Rep:
            Chromosome undetermined scaffold_155, whole genome
            shotgun sequence - Paramecium tetraurelia
          Length = 1047

 Score =  122 bits (294), Expect = 8e-26
 Identities = 205/1023 (20%), Positives = 449/1023 (43%), Gaps = 93/1023 (9%)

Query: 620  ESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELA 679
            +SQ F L    H L++ Y+ + D++   ++ Q DQ  +  K  +++  ID+  A   +L+
Sbjct: 58   DSQNFHLRSSQH-LEKSYN-LTDRIFSPARKQ-DQSPNLRKKENIKI-IDSYEARYGKLS 113

Query: 680  ---LVIEN-LKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISEL 735
               L ++N ++ D+++    I +LE    +   KLQ   Q N+     L +   E+I  L
Sbjct: 114  TENLQLQNQIQADQQKYNKIINELEIQLSNQTYKLQTE-QHNIKQQQLLLQKKNEEIQLL 172

Query: 736  LAKINHEEQSKIQ-TQFGIDAKIQERDL--YIENIESELSKYKSRICRLE-ESIAVMEDR 791
            + ++   E   IQ +Q  + +  + ++L  YI+N+E EL   K ++     +S   +E+ 
Sbjct: 173  VNELKKNETKFIQISQNNVQSVDENQNLKAYIQNLEYELQNLKQQVQDTHFKSARQIEET 232

Query: 792  RYSLERKAD-----QLGSYLQEKQKAYS---EYTIQEDELVNRLAVLMDHDRVVEK---Q 840
            +  +E         QL    Q+ Q+  S   +  IQE +  ++L    D+  V EK   Q
Sbjct: 233  KIKVENDCSHQSQIQLKDIQQQHQQILSKKNDQLIQEQQKYSKLLGQFDN-LVNEKNKMQ 291

Query: 841  LLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQL 900
            LL  + ++++L  + Q+  +     +  L +M  H    +      D    +   +Q Q+
Sbjct: 292  LLIDDLQDEKLVIQQQLQQQNQMCEEFRLKNMSLHKEVQLVH----DKQAKQELSHQKQI 347

Query: 901  RDLESNLKRITHEHQTLIVQKK-KEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQ 959
            ++L    K+   + Q   +Q++  E E      N Q +  IR+ +   ++ E N + +  
Sbjct: 348  QEL----KQYYEQQQINNLQRRLNETELKHSTENQQQDQIIRELQAQLQQSENNYQVMKT 403

Query: 960  LEAQL----QEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLN 1015
              A+L    QE +  I+ L   +E +NK      D  +Q+QQ       +Q + + +K  
Sbjct: 404  ENAKLYAIDQEQEKEIKILQQELERINKFK----DLEIQQQQEDLQKLKQQLLEQSSKYQ 459

Query: 1016 ALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLA-QFTTKLENM----EEEMQRVSKQ 1070
              L +  ++ +  N   +  ++   ++  + E+ +  Q+ T ++ +    ++++Q + +Q
Sbjct: 460  TKLHELSKQQVIANDIKSELELQ-KNVTKEIEASIREQWETDIQELKGFNQQQLQNLEEQ 518

Query: 1071 LLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSD-DANNVD 1129
            +      NE+L I  R++D+QI E K  +   + +I   +  +  +  +   + +    +
Sbjct: 519  IKFLNLENEKLIIQSRKKDEQINEYKLNQQLLDNSINGLKHQLSDTEKQKQKELEDYQFE 578

Query: 1130 XXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLETLNTELTGHD 1189
                        +K+Q+E++ ++++   Q+Q AK      E  T  I+LE  +++   + 
Sbjct: 579  LENFKKELKEQNVKLQQEKQLMEQQLKQQKQRAK------ELETAKIELEFSSSQQIQN- 631

Query: 1190 VVNQEQINQLKSKLEQLNTENDNLLSTVAELRSSISSAVDQ--RGFEIAELWKQHLAQ-- 1245
               QEQI Q   ++ Q N+E     S +   +  ++ A  Q     + A+++ + L +  
Sbjct: 632  --YQEQIKQKDWQISQFNSEKQKFESLLKSNKERLTQAEFQVVELKQSADIYLKELEEST 689

Query: 1246 READFQKTEHELRVQLSAFE-SKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEE 1304
            ++ D ++++   +        S+Y+Q ++  +     + N+I   ++  SL + + + ++
Sbjct: 690  QQRDLERSQFNQKFGFQETRISQYKQAINQYEIEIHNQNNQIDKAQK--SLDHAMLESQK 747

Query: 1305 HLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQE 1364
             +   +++   +++QI  L  +++  +  F                 L+ ++   K ++ 
Sbjct: 748  KIEESRKREQKLLDQIANLNLQLQSNEDQFIKYQEEHKESNKQIEQLLQEKDSLIKSLEN 807

Query: 1365 QSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEIYQKTHEYT 1424
            Q      E+  ++K                  + E +  +   Q+E + + +  +     
Sbjct: 808  Q-----KEKLVEVKNELTEEIEQLNQKIQNYAEGENQRQDWEFQVENEKAVLNNEIEILQ 862

Query: 1425 ITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYETMQ--KESEI 1482
              L Q+  +   ++QQ    E +++D    KE     LR ++ +N  H E  +  K+  I
Sbjct: 863  QKLDQKESKLNQIQQQFSNLEIQLQD----KEVLYDSLRRQIDQNYVHVEDYEQLKQKNI 918

Query: 1483 ERVKLIEELN----VKITESVSLNKQVAELNKAL---EEEVAKTNEM--QTALENQEI-- 1531
              +  I EL        +E  SL +QV +L   L   E+E  +T E   +   +N+++  
Sbjct: 919  NLLNEIHELESSQLKSNSEKQSLRRQVEKLKSDLELKEQEFEQTFEQLNKRRGDNEDVAK 978

Query: 1532 ---EIVTLNDEITNLQNMVRASSSKI---QKHVSFASDTKQGRDEQLDNTMNKELLDAVP 1585
               EI  LN E+++ Q +++A S ++   ++      +       QL+ T  KEL+  + 
Sbjct: 979  LTKEIQRLNFELSDAQTLLQAKSEQLNIMRRENDDQLEQLNRMKRQLNQTSEKELIRRID 1038

Query: 1586 RAE 1588
            ++E
Sbjct: 1039 KSE 1041



 Score =  111 bits (268), Expect = 1e-22
 Identities = 129/670 (19%), Positives = 313/670 (46%), Gaps = 56/670 (8%)

Query: 450  AQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKV--QEQLKQELNDEIKDVNVKDLIEKLKS 507
            A+ +L HQ+ ++     +     + +N + +   + +LK    ++ +D  +++L  +L+ 
Sbjct: 337  AKQELSHQKQIQELKQYY---EQQQINNLQRRLNETELKHSTENQQQDQIIRELQAQLQQ 393

Query: 508  AEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTEELHHL 567
            +E     +  E    N  +  +    + ++K +Q+ ++  +K  D   EI +  E+L  L
Sbjct: 394  SENNYQVMKTE----NAKLYAIDQEQEKEIKILQQELERINKFKDL--EIQQQQEDLQKL 447

Query: 568  SQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDLV 627
             Q++ E +  K   +LH  +    ++I +D+ K  +E++      ++A S+ E  + D+ 
Sbjct: 448  KQQLLE-QSSKYQTKLH--ELSKQQVIANDI-KSELELQKNVTKEIEA-SIREQWETDIQ 502

Query: 628  QELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKELALVIENLKL 687
            +     QQ+   +E+++  ++ L+++++   I+S   +EQI+    +++ L   I  LK 
Sbjct: 503  ELKGFNQQQLQNLEEQIKFLN-LENEKLI--IQSRKKDEQINEYKLNQQLLDNSINGLK- 558

Query: 688  DKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEK---MSAEKISELLAKINHEEQ 744
               QL  T K  + + ED   +L+N+ +E  +   KL++   +  +++ +   +    E 
Sbjct: 559  --HQLSDTEKQKQKELEDYQFELENFKKELKEQNVKLQQEKQLMEQQLKQQKQRAKELET 616

Query: 745  SKIQTQFGIDAKIQ-------ERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLER 797
            +KI+ +F    +IQ       ++D  I    SE  K++S +   +E +   E +   L++
Sbjct: 617  AKIELEFSSSQQIQNYQEQIKQKDWQISQFNSEKQKFESLLKSNKERLTQAEFQVVELKQ 676

Query: 798  KADQLGSYLQEKQKAYSEYTIQEDELVNRLAV----LMDHDRVVEKQLLEIEHENKELQK 853
             AD    YL+E +++  +  ++  +   +       +  + + + +  +EI ++N ++ K
Sbjct: 677  SAD---IYLKELEESTQQRDLERSQFNQKFGFQETRISQYKQAINQYEIEIHNQNNQIDK 733

Query: 854  KNQIL----LEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKR 909
              + L    LE  + ++ S    Q+  + +     +    E +  KYQ + ++    +++
Sbjct: 734  AQKSLDHAMLESQKKIEESRKREQKLLDQIANLNLQLQSNEDQFIKYQEEHKESNKQIEQ 793

Query: 910  ITHEHQTLIVQ---KKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQE 966
            +  E  +LI     +K+++ +++ E   +IE   +  +   E   +  ++  Q+E +   
Sbjct: 794  LLQEKDSLIKSLENQKEKLVEVKNELTEEIEQLNQKIQNYAEGENQRQDWEFQVENEKAV 853

Query: 967  YKNNIENLNMNVEE----LNKMNLELIDKHVQKQQTQSP-DYTEQYINEINKLNA----L 1017
              N IE L   +++    LN++  +  +  +Q Q  +   D   + I++ N ++      
Sbjct: 854  LNNEIEILQQKLDQKESKLNQIQQQFSNLEIQLQDKEVLYDSLRRQIDQ-NYVHVEDYEQ 912

Query: 1018 LKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQH 1077
            LKQK+  ++    ++ ++Q+   S       ++ +  + LE  E+E ++  +QL   +  
Sbjct: 913  LKQKNINLLNEIHELESSQLKSNSEKQSLRRQVEKLKSDLELKEQEFEQTFEQLNKRRGD 972

Query: 1078 NEELQILVRE 1087
            NE++  L +E
Sbjct: 973  NEDVAKLTKE 982



 Score = 86.2 bits (204), Expect = 7e-15
 Identities = 163/842 (19%), Positives = 368/842 (43%), Gaps = 78/842 (9%)

Query: 220  KMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAARFEISL-EHSKLAQEL 278
            +++E  I +E +   + Q  LKDI+ +  +I S +    + E  ++   L +   L  E 
Sbjct: 228  QIEETKIKVENDCSHQSQIQLKDIQQQHQQILSKKNDQLIQEQQKYSKLLGQFDNLVNEK 287

Query: 279  EQXXXXXXXXXXXXXXLAKQSIEPS--CEEKTEIEEKGSLEIANMTELTKKIELLEHLNC 336
             +              + +Q  + +  CEE          E+  + +   K EL      
Sbjct: 288  NKMQLLIDDLQDEKLVIQQQLQQQNQMCEEFRLKNMSLHKEVQLVHDKQAKQELSHQKQI 347

Query: 337  Q-IRQTNKELE-NKLATMGTESKAVSSPSKKGSPLISRK------SGRNTASKMKSPWSQ 388
            Q ++Q  ++ + N L     E++   S   +    I R+         N    MK+  ++
Sbjct: 348  QELKQYYEQQQINNLQRRLNETELKHSTENQQQDQIIRELQAQLQQSENNYQVMKTENAK 407

Query: 389  LSSETLNQDTDKKINKNEIAKL----EMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXG 444
            L +    Q+ + KI + E+ ++    ++ IQ   +DL   +  + E+ +           
Sbjct: 408  LYAIDQEQEKEIKILQQELERINKFKDLEIQQQQEDLQKLKQQLLEQSSKYQTKLHELSK 467

Query: 445  KDTLIAQL--QLEHQQHMEGPSLIHVGTNTE-DVNEIAKVQEQLKQELNDEIKDVNVKD- 500
            +  +   +  +LE Q+++       +    E D+ E+    +Q  Q L ++IK +N+++ 
Sbjct: 468  QQVIANDIKSELELQKNVTKEIEASIREQWETDIQELKGFNQQQLQNLEEQIKFLNLENE 527

Query: 501  -LIEKLKSAEEQITQ-------LNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSD 552
             LI + +  +EQI +       L++ I+     +   +   + +L+  Q  ++NF K  +
Sbjct: 528  KLIIQSRKKDEQINEYKLNQQLLDNSINGLKHQLSDTEKQKQKELEDYQFELENFKK--E 585

Query: 553  SNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVD--YDSGRMIES---DVYKKMIEMEN 607
              ++ V+L +E   + Q++ + ++    L+   ++  + S + I++    + +K  ++  
Sbjct: 586  LKEQNVKLQQEKQLMEQQLKQQKQRAKELETAKIELEFSSSQQIQNYQEQIKQKDWQISQ 645

Query: 608  LAETRLKAISLLESQKFDLVQ-ELHILQQKYD-EVEDKLADISQLQSDQVCSEI--KSVH 663
                + K  SLL+S K  L Q E  +++ K   ++  K  + S  Q D   S+   K   
Sbjct: 646  FNSEKQKFESLLKSNKERLTQAEFQVVELKQSADIYLKELEESTQQRDLERSQFNQKFGF 705

Query: 664  LEEQIDAL--SASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLT 721
             E +I     + ++ E+ +  +N ++DK Q     K L++   +   K++   +    L 
Sbjct: 706  QETRISQYKQAINQYEIEIHNQNNQIDKAQ-----KSLDHAMLESQKKIEESRKREQKLL 760

Query: 722  DKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRL 781
            D++  ++ +  S     I ++E+ K ++   I+  +QE+D  I+++E++  K        
Sbjct: 761  DQIANLNLQLQSNEDQFIKYQEEHK-ESNKQIEQLLQEKDSLIKSLENQKEK-------- 811

Query: 782  EESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQL 841
                  + + +  L  + +QL   +Q   +  ++    E ++ N  AVL +   +++++L
Sbjct: 812  ------LVEVKNELTEEIEQLNQKIQNYAEGENQRQDWEFQVENEKAVLNNEIEILQQKL 865

Query: 842  LEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKA--NRTDLAESESTKYQT- 898
                 + KE  K NQI  ++  NL+I L D +  Y++L  +   N   + + E  K +  
Sbjct: 866  -----DQKE-SKLNQIQ-QQFSNLEIQLQDKEVLYDSLRRQIDQNYVHVEDYEQLKQKNI 918

Query: 899  ----QLRDLESNLKRITHEHQTLIVQKKKEIEDLEI---EFNTQIESAIRDKKVLNEKYE 951
                ++ +LES+  +   E Q+L  Q +K   DLE+   EF    E  +  ++  NE   
Sbjct: 919  NLLNEIHELESSQLKSNSEKQSLRRQVEKLKSDLELKEQEFEQTFEQ-LNKRRGDNEDVA 977

Query: 952  KNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEI 1011
            K  + + +L  +L + +  ++  +  +  + + N + +++  + ++  +    ++ I  I
Sbjct: 978  KLTKEIQRLNFELSDAQTLLQAKSEQLNIMRRENDDQLEQLNRMKRQLNQTSEKELIRRI 1037

Query: 1012 NK 1013
            +K
Sbjct: 1038 DK 1039



 Score = 85.4 bits (202), Expect = 1e-14
 Identities = 157/807 (19%), Positives = 344/807 (42%), Gaps = 95/807 (11%)

Query: 859  LEENQNLQISLSDMQQHYNAL-VEKANRTDLAESESTKYQTQLRDLESNLKRITHEHQT- 916
            L + +N++I +   +  Y  L  E     +  +++  KY   + +LE  L   T++ QT 
Sbjct: 93   LRKKENIKI-IDSYEARYGKLSTENLQLQNQIQADQQKYNKIINELEIQLSNQTYKLQTE 151

Query: 917  --------LIVQKKKE-----IEDLEIEFNTQIESAIRDKKVLNEK-----YEKNIEYVT 958
                    L++QKK E     + +L+      I+ +  + + ++E      Y +N+EY  
Sbjct: 152  QHNIKQQQLLLQKKNEEIQLLVNELKKNETKFIQISQNNVQSVDENQNLKAYIQNLEYEL 211

Query: 959  Q-LEAQLQE--YKN--NIENLNMNVEE--LNKMNLELIDKHVQKQQTQSPDYTEQYINEI 1011
            Q L+ Q+Q+  +K+   IE   + VE    ++  ++L D   Q QQ  S    +Q I E 
Sbjct: 212  QNLKQQVQDTHFKSARQIEETKIKVENDCSHQSQIQLKDIQQQHQQILSKK-NDQLIQEQ 270

Query: 1012 NKLNALLKQKDEEIIALNQ------KINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQ 1065
             K + LL Q D  +   N+       + + ++     +        +F  K  ++ +E+Q
Sbjct: 271  QKYSKLLGQFDNLVNEKNKMQLLIDDLQDEKLVIQQQLQQQNQMCEEFRLKNMSLHKEVQ 330

Query: 1066 RV-SKQLLDSKQHNEELQILVREQDDQ-----IKELKETKLTFEMNIPKTEGMIISSTIE 1119
             V  KQ      H +++Q L +  + Q      + L ET+L       + +  II     
Sbjct: 331  LVHDKQAKQELSHQKQIQELKQYYEQQQINNLQRRLNETELKHSTE-NQQQDQIIRELQA 389

Query: 1120 PMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKLNTELQECYTKIIQLE 1179
             +    NN                + +E+E  +E  +LQ++  ++N        K ++++
Sbjct: 390  QLQQSENNYQVMKTENAKLYA---IDQEQE--KEIKILQQELERINK------FKDLEIQ 438

Query: 1180 TLNTELTGHDVVNQEQINQLKSKLEQLNTEN--DNLLSTVAELRSSISSAVDQRGFEIAE 1237
                +L        EQ ++ ++KL +L+ +    N + +  EL+ +++  ++     I E
Sbjct: 439  QQQEDLQKLKQQLLEQSSKYQTKLHELSKQQVIANDIKSELELQKNVTKEIEA---SIRE 495

Query: 1238 LWKQHLAQREADFQKTEHELRVQLSAFESKYEQLLDSVQSSTQEE------TNKIVTMEQ 1291
             W+  + + +   Q+    L  Q+     + E+L+  +QS  ++E       N+ +    
Sbjct: 496  QWETDIQELKGFNQQQLQNLEEQIKFLNLENEKLI--IQSRKKDEQINEYKLNQQLLDNS 553

Query: 1292 VTSLQNKLQD----KEEHLRNLQEKYADVINQIEILRSEIEDEK-VAFXXXXXXXXXXXX 1346
            +  L+++L D    K++ L + Q +  +   +++    +++ EK +              
Sbjct: 554  INGLKHQLSDTEKQKQKELEDYQFELENFKKELKEQNVKLQQEKQLMEQQLKQQKQRAKE 613

Query: 1347 XXXXDLRTENQSYKQMQ--EQSILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLE 1404
                 +  E  S +Q+Q  ++ I   + + +Q                 R+  AE +V+E
Sbjct: 614  LETAKIELEFSSSQQIQNYQEQIKQKDWQISQFNSEKQKFESLLKSNKERLTQAEFQVVE 673

Query: 1405 LTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRL 1464
            L    ++   E+ + T +  +  +Q N +F     ++ +Y++ I     E  ++   +  
Sbjct: 674  LKQSADIYLKELEESTQQRDLERSQFNQKFGFQETRISQYKQAINQYEIEIHNQNNQID- 732

Query: 1465 KMHENANH--YETMQK--ESEIERVKLIEE---LNVKITES----VSLNKQVAELNKALE 1513
            K  ++ +H   E+ +K  ES     KL+++   LN+++  +    +   ++  E NK +E
Sbjct: 733  KAQKSLDHAMLESQKKIEESRKREQKLLDQIANLNLQLQSNEDQFIKYQEEHKESNKQIE 792

Query: 1514 EEVAKTNEMQTALENQEIEIVTLNDEITNLQNMVRASSSKIQKHVSFASDTKQGRDEQLD 1573
            + + + + +  +LENQ+ ++V + +E+T     +   + KIQ +        +G +++ D
Sbjct: 793  QLLQEKDSLIKSLENQKEKLVEVKNELT---EEIEQLNQKIQNYA-------EGENQRQD 842

Query: 1574 NTMNKELLDAVPRAELDLAMYMLHQRD 1600
                 E   AV   E+++    L Q++
Sbjct: 843  WEFQVENEKAVLNNEIEILQQKLDQKE 869



 Score = 39.1 bits (87), Expect = 0.99
 Identities = 86/442 (19%), Positives = 179/442 (40%), Gaps = 34/442 (7%)

Query: 212  EDTKQQMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRI--SSLEEANKLLEAAR---FE 266
            ++ K+Q  K+Q+    ME + K +KQR  K++E+  + +  SS ++     E  +   ++
Sbjct: 584  KELKEQNVKLQQEKQLMEQQLKQQKQR-AKELETAKIELEFSSSQQIQNYQEQIKQKDWQ 642

Query: 267  ISLEHSKLA--QELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTEL 324
            IS  +S+    + L +                KQS +   +E  E  ++  LE    ++ 
Sbjct: 643  ISQFNSEKQKFESLLKSNKERLTQAEFQVVELKQSADIYLKELEESTQQRDLE---RSQF 699

Query: 325  TKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISRKSGRNTASKMKS 384
             +K    E    Q +Q   + E ++     +    +  S   + L S+K    +  + + 
Sbjct: 700  NQKFGFQETRISQYKQAINQYEIEIHNQNNQIDK-AQKSLDHAMLESQKKIEESRKREQ- 757

Query: 385  PWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXG 444
               +L  +  N +   + N+++  K +   +  NK +   E ++ EKD+           
Sbjct: 758  ---KLLDQIANLNLQLQSNEDQFIKYQEEHKESNKQI---EQLLQEKDSLIKSLENQKEK 811

Query: 445  KDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVK-DLIE 503
               +  +L  E +Q  +       G N     E     E  K  LN+EI+ +  K D  E
Sbjct: 812  LVEVKNELTEEIEQLNQKIQNYAEGENQRQDWEFQVENE--KAVLNNEIEILQQKLDQKE 869

Query: 504  -KLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIVRLTE 562
             KL   ++Q + L  EI   +K ++    + + ++ Q    ++++ ++   N   + L  
Sbjct: 870  SKLNQIQQQFSNL--EIQLQDKEVL--YDSLRRQIDQNYVHVEDYEQLKQKN---INLLN 922

Query: 563  ELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLA----ETRLKAISL 618
            E+H L     +   EK +L+  +    S   ++   +++  E  N      E   K    
Sbjct: 923  EIHELESSQLKSNSEKQSLRRQVEKLKSDLELKEQEFEQTFEQLNKRRGDNEDVAKLTKE 982

Query: 619  LESQKFDLVQELHILQQKYDEV 640
            ++   F+L     +LQ K +++
Sbjct: 983  IQRLNFELSDAQTLLQAKSEQL 1004


>UniRef50_A5E429 Cluster: Putative uncharacterized protein; n=1;
            Lodderomyces elongisporus NRRL YB-4239|Rep: Putative
            uncharacterized protein - Lodderomyces elongisporus
            (Yeast) (Saccharomyces elongisporus)
          Length = 2032

 Score =  122 bits (294), Expect = 8e-26
 Identities = 255/1402 (18%), Positives = 596/1402 (42%), Gaps = 137/1402 (9%)

Query: 236  KQRLLKDIESKDVRISSLEEANKLLEAARFEISLEHSKLAQELEQXXXXXXXXXXXXXXL 295
            K+ + K I S   RI  +E A     ++    S   S   QE+                 
Sbjct: 198  KEEISKIINSAISRIIPIERATTTTSSSSSSSSSSSSSSTQEVVDSIAETLTNLINSGSQ 257

Query: 296  AKQSIEPSCEEKTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTE 355
             +Q +E       +IE         + E+  K    ++ N ++++ N  LE+KL +   +
Sbjct: 258  NQQYLELDSSSTIKIE---------LEEVKSKFSAADNDNIRLKEENDMLESKLQSSQQQ 308

Query: 356  SK----AVSSPSKKGSPLISRKSGRNTA-SKMKSPWSQLSSETLN---QDTDKKINKNEI 407
            SK     +     K   L    +  N   +++K   SQ  S  L+   Q T   + +N  
Sbjct: 309  SKELQHVIEDLQDKIRHLAKSFAELNRKFAELKDTCSQQESHYLSKLEQLTSSNVEQNR- 367

Query: 408  AKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXXXGKDT--LIAQLQLEHQQHMEG--- 462
             KL  +++ LN    +KE   ++ +             ++  L  +LQ   Q++ E    
Sbjct: 368  -KLASLVEELNTR--EKENFANKLELTKAKSELSFLRNESKWLHEELQSSQQKYSEALKQ 424

Query: 463  PSLIHVGTNTEDVNEIAKVQ--EQLKQELNDEIKDVNVKDLIEKLKSAEEQI------TQ 514
                   T++  +N  +K++  EQL +    E+  +N     E  K+ + ++      TQ
Sbjct: 425  SGQTQSSTDSAMLNTQSKLKNAEQLIKSHETELLQLNSSLAAETKKNTDLEVRLKKIETQ 484

Query: 515  LNDEIDAANK--NMIKVKSNHK-LKLKQMQKTIDNFSKVSDSNKEIVRLT-----EELHH 566
               +I+A  +  +++K++S  +  ++K++++ ++   K SD   + + L+     +E+  
Sbjct: 485  SLLDINAKQELIDLMKIQSRQRESRIKELEEYVNQILKNSDEAFKHLELSVSEKDDEIAV 544

Query: 567  LSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISLLESQKFDL 626
            L +K+  +EE         +  ++     +  Y    E ++ +      ISLL S+   +
Sbjct: 545  LQEKLQRVEEALAADMAQTLSGENSEQTFASGYGSSSEFDSGSGPG--QISLLYSEFIHV 602

Query: 627  VQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQI-DALSASKKELALVIENL 685
             +EL + + + +++E +L +    + D +   +   + ++Q  +++    ++   +++N 
Sbjct: 603  KKELTLERMQKEKLEGELEEFV-FEMDSLKRALGDFNAQKQYYESVRLDLQDQITILQNE 661

Query: 686  KLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEEQS 745
            KL+ E+     + ++ D +  + +L+  +++       L +     +     + NHE+  
Sbjct: 662  KLELEKSQRHFRAVQKDNDLEVQRLKQTLKD-------LGRQLCFSLIHTKIRDNHEDPL 714

Query: 746  KIQTQFGIDAKIQERDLYIENIESELSK--------YKSRI---CRLEESIAVMEDRRYS 794
             +  +  I+  I       E  ES+ SK        +K  I    R EE ++ + +    
Sbjct: 715  SLAEKTFIENVIDRTGNDEEFAESDTSKLISERLLEFKDLIELRQRNEELLSAVRELSTR 774

Query: 795  LER-KADQLGSYLQEKQKAYSEYTIQEDEL---VNRLAVLMDHDRVVEKQLLEIEHENKE 850
            LE  +A Q  + +    +A     + ++EL    N++++L+     +EK + E +  +  
Sbjct: 775  LESGEAAQNSAEIAAIDEAQETILMLQNELESTCNKMSLLVKERDALEKIVRERDGGDAG 834

Query: 851  LQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRI 910
              K N + +    + ++  ++ ++     +EK       ++   K + +  +++  L ++
Sbjct: 835  NDKSNGLSIANFGHNEVE-NEEKEKIRIKMEKQQEQKQKQTGEEKNEKEREEVDKELSQV 893

Query: 911  THE-HQTLIVQKKKEIE-DLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYK 968
              +  +    + K ++E   ++    Q E  ++  +  N++   +IE+  Q   Q+  + 
Sbjct: 894  ILQLREVKDARDKLKVELAAQVRAIEQAELKVQSLQRTNDRLLSDIEHANQ---QVNFWN 950

Query: 969  NNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKDEEIIAL 1028
               E L   + E   + L L  K  +K+ T      +    E +   ++ K  +  I+ L
Sbjct: 951  KQFEKLEGQLNEKALLMLGLEAKLNEKETT-----VKSLCLEKDFALSMQKSLESTIVEL 1005

Query: 1029 NQ--KINNAQVSYMSMVSDYE-SKLAQFTTKLENMEEEMQRVSKQLLDSKQH----NEEL 1081
             Q  KI N Q + + + ++ + S+LA+   KL+++E E   + ++L + +       ++ 
Sbjct: 1006 RQDKKIMNEQFAVLQLTAETKNSELAKLAQKLDDLESERLAIQRKLNERESKILILTDQR 1065

Query: 1082 QILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSDDAN-NVDXXXXXXXXXXX 1140
             + ++ Q  +++++ +      ++  K    + +  +E + D A+ +V            
Sbjct: 1066 DMSMKSQQVKLEQINDLSSQL-LHARKELSQMQAIVLELLPDSASQSVARQQMEDELKEY 1124

Query: 1141 XLKVQEEEEFIQERS-VLQEQSAKLNTELQECYTKIIQLET----LNTELTGHDVVNQEQ 1195
              ++ E    +++++  + E + K   EL     K+   ET     + E+T  + V   +
Sbjct: 1125 GDRISELTNQLKDKNETILEATTKFEKELSSMSEKLKSKETEKVAADGEITRLNGVISSK 1184

Query: 1196 INQLKSKLEQLNTENDNLLSTV--AELRSSISSAV-DQRGFEIAELWKQH-----LAQRE 1247
            I ++++  +Q  TE D  ++ +  AE ++  S +V D+    I +L  Q      L Q+ 
Sbjct: 1185 IQEMENMKKQYTTELDETVAKLKAAESKTKSSQSVEDELKKTIEDLQDQRDISKGLEQKI 1244

Query: 1248 ADFQKTEHELRVQLSAFES----------KYEQLLDSVQSSTQEETNKIVTMEQVTSLQN 1297
             ++      L  Q++A++S            +  L+ V+++ ++E N+I++  Q   LQ 
Sbjct: 1245 REYHTQVSTLVQQINAYKSDSDSNQELIQSLQDQLEQVRATRKDEENQILS--QKLELQT 1302

Query: 1298 KLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQ 1357
            +  +  + +  LQ +   ++NQ+E L S    E                    +  + ++
Sbjct: 1303 ENAELLKKIEELQGQNTLLLNQLE-LSSSSNQETNPSGEKSQDIAQIISFLRREKESSDE 1361

Query: 1358 SYKQMQEQSI-LNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLELKDSEI 1416
               +++E+++ L I  EN Q K ++             VN+ + K +    Q++L   ++
Sbjct: 1362 KLPKLEEENVALKIKLENLQNKVNNFNAGAPSASINLTVNNEQQKQI----QMQLDQLKL 1417

Query: 1417 YQKTHEYTITLT-QRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENANHYET 1475
            +++++   +    ++N E  N+  ++ + +  +E +T    ++L+ L +           
Sbjct: 1418 FKESNSVLVNENLKKNQELVNLNSEVTKIKLELEKITQLYNNQLSHLSV----------- 1466

Query: 1476 MQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQEIE-IV 1534
                 E +RVKL  + NV++ + +S N + +E  K+   E+AK  E    L+ +  + I 
Sbjct: 1467 -----EQQRVKLFSDENVRLKQILSANSRTSEQTKSPAPEIAKMQEQMDKLKTKANDRIA 1521

Query: 1535 TLNDEITNLQNMVRASSSKIQK 1556
             L  E+ +   +V+A  ++I+K
Sbjct: 1522 VLRRELDSKDGIVKAKEAEIEK 1543



 Score = 57.6 bits (133), Expect = 3e-06
 Identities = 160/839 (19%), Positives = 342/839 (40%), Gaps = 81/839 (9%)

Query: 141  LGDVTHLSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXX 200
            L D+ H +  +   +     L+ ++      +L L+ K+NEK+  +    K+        
Sbjct: 936  LSDIEHANQQVNFWNKQFEKLEGQLNEKALLMLGLEAKLNEKETTV----KSLCLEKDFA 991

Query: 201  XXXXXXXXXXXEDTKQQMTKMQENFIAME--AEWKDEK----QRLLKDIESKDVRISSL- 253
                        + +Q    M E F  ++  AE K+ +     + L D+ES+ + I    
Sbjct: 992  LSMQKSLESTIVELRQDKKIMNEQFAVLQLTAETKNSELAKLAQKLDDLESERLAIQRKL 1051

Query: 254  -EEANKLL---EAARFEISLEHSKLAQ--ELEQXXXXXXXXXXXXXXLAKQSIEPSCEE- 306
             E  +K+L   +     +  +  KL Q  +L                +  + +  S  + 
Sbjct: 1052 NERESKILILTDQRDMSMKSQQVKLEQINDLSSQLLHARKELSQMQAIVLELLPDSASQS 1111

Query: 307  --KTEIEEKGSLEIANMTELTKKIELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSK 364
              + ++E++       ++ELT +   L+  N  I +   + E +L++M  + K+  +   
Sbjct: 1112 VARQQMEDELKEYGDRISELTNQ---LKDKNETILEATTKFEKELSSMSEKLKSKETEKV 1168

Query: 365  KGSPLISRKSG--RNTASKMKSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLV 422
                 I+R +G   +   +M++   Q ++E        K  +++    + V   L K + 
Sbjct: 1169 AADGEITRLNGVISSKIQEMENMKKQYTTELDETVAKLKAAESKTKSSQSVEDELKKTIE 1228

Query: 423  DKEYVISEKDTXXXXXXXXXXGKDTLIAQLQLEHQQHMEGPSLIH-VGTNTEDVNEIAKV 481
            D +                     TL+ Q+            LI  +    E V    K 
Sbjct: 1229 DLQDQRDISKGLEQKIREYHTQVSTLVQQINAYKSDSDSNQELIQSLQDQLEQVRATRKD 1288

Query: 482  QEQ--LKQELNDEIKDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQ 539
            +E   L Q+L  E++  N  +L++K++  + Q T L ++++ ++ +  +   + + K + 
Sbjct: 1289 EENQILSQKL--ELQTENA-ELLKKIEELQGQNTLLLNQLELSSSSNQETNPSGE-KSQD 1344

Query: 540  MQKTIDNFSKVSDSNKE-IVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDV 598
            + + I    +  +S+ E + +L EE   L  K+  L+ +  N             + ++ 
Sbjct: 1345 IAQIISFLRREKESSDEKLPKLEEENVALKIKLENLQNKVNNFNAGAPSASINLTVNNE- 1403

Query: 599  YKKMIEMENLAETRL--KAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVC 656
             +K I+M+ L + +L  ++ S+L ++     QEL  L  +  +++ +L  I+QL ++Q  
Sbjct: 1404 QQKQIQMQ-LDQLKLFKESNSVLVNENLKKNQELVNLNSEVTKIKLELEKITQLYNNQ-- 1460

Query: 657  SEIKSVHLEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQE 716
              +  + +E+Q   L +         EN++L K+ L    +  E  K       +  +QE
Sbjct: 1461 --LSHLSVEQQRVKLFSD--------ENVRL-KQILSANSRTSEQTKSPAPEIAK--MQE 1507

Query: 717  NMDLTDKLEKMSAEKISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKS 776
             M   DKL+     K ++ +A +  E  SK       D  ++ ++  IE I+ EL    +
Sbjct: 1508 QM---DKLK----TKANDRIAVLRRELDSK-------DGIVKAKEAEIEKIKQELQAANA 1553

Query: 777  RICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRV 836
            +    E++ +V  D +  +E+K   +   L+  ++  ++   +++ELV +LA L      
Sbjct: 1554 K----EQNKSVNGDSK-DVEKKLADVNRELKTVKEESAKLVGEKNELVKQLATLK----- 1603

Query: 837  VEKQLLEIEHENKELQKKNQILLEENQNLQISLSDM-QQHYNALVEKANRTDLAESESTK 895
              + +       K +       +          +        A    A    +   E  K
Sbjct: 1604 -AQNMKSGSTAGKSVTTPTAAAVVGGATTAAGATAAGATAAGATAAGATAAAVKNGEVPK 1662

Query: 896  YQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNI 954
             + Q+R+L+ +L+++  E Q  + ++K +   LE+E   + +  +  +KV  EKYEK +
Sbjct: 1663 LEAQIRELKQSLEKMQQESQKKLDEEKSKTR-LEVEKKFEFKLRLLTRKV--EKYEKEL 1718


>UniRef50_UPI00006A0892 Cluster: Hook-related protein 1; n=1; Xenopus
            tropicalis|Rep: Hook-related protein 1 - Xenopus
            tropicalis
          Length = 1347

 Score =  122 bits (293), Expect = 1e-25
 Identities = 212/1098 (19%), Positives = 470/1098 (42%), Gaps = 92/1098 (8%)

Query: 494  KDVNVKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDS 553
            + ++V DL  KL+ A +++ +  +E+   N+  +++      KL Q  + +   + +S  
Sbjct: 171  RSLHVADLQSKLRRARQELEEKGEEL-LDNQQHVEMLEAELRKLHQQVRELSAMAALSRG 229

Query: 554  NK-EIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVY--KKMIEMENLAE 610
             + E+  L E       +V  L E+   +++        +     +   K+++E +  AE
Sbjct: 230  YRDELDALRERSRRAEAQVNALNEKLRTMEIFQRSLQEEKEFSRALLEDKEVLEHQLAAE 289

Query: 611  T-RLKAISLLESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQI- 668
              R + + L E +K  L + +  L+ + D  E +        +  +  E++ +  E Q  
Sbjct: 290  RERSEKLRLCEKEKHSLEERIQRLEMERDS-ECQRVQFLLHDNLTLAEEVRVLREETQRG 348

Query: 669  -DALSASKKELALVIENLK--LD-KEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKL 724
             + +  S  +   V E  +  LD   +L   +  LE + +++  +LQ    E  D  +K 
Sbjct: 349  WERVYESHGDTVPVWEREQDVLDLNSELSQALLRLEKENQNLRERLQGLSGETPDPKNKG 408

Query: 725  EKMSAEKISELLAKIN----HEEQSKIQTQFGIDAKIQER-DLYIENIESELSKYKSRIC 779
            + +  E      +K+     H E+S ++ Q   D+  QE+     E ++ +L +    I 
Sbjct: 409  QHVQTEGEQGRNSKVQIMTVHLEESPLE-QKSCDSYWQEKVSCETEALKRQLEESALEID 467

Query: 780  RLEESIAVMEDRRYSLERKADQLGSY---LQEKQKAYSEYTI----QEDELVNRLAVLMD 832
             L+  +   +D   + + +  +  +    LQ K +  +E  +    Q D+ +    +L +
Sbjct: 468  SLKRQLKEKQDEAQNQQNQLSESTTEKNALQRKLQGNAEEILSLQKQLDKSIKECHLLKE 527

Query: 833  HDRVVEKQLLEIEHE--NKELQKKNQILLEENQ---NLQISLSDMQQHYNALVEKANRTD 887
              + + K+ L+++H   N+E+Q + + + E ++   +LQ  L D+ +    L ++   +D
Sbjct: 528  ELQGMVKESLKMQHHDGNEEMQTQKRKVEESSEEILSLQRQLQDIVKKEELLQKQLEISD 587

Query: 888  -LAESESTKYQTQLRDLESNLKRITHEHQTLIVQKKKEIEDLEIEFNTQ---IESAIRDK 943
             + E++      +  ++   L+ IT E Q+L    K+++E+ E E   Q   ++ ++ + 
Sbjct: 588  KMVETQHRNLAERSEEIRQ-LQEITGEVQSL----KRQLEETEKEKQCQQRHLQESVLEA 642

Query: 944  KVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQQTQSPDY 1003
            + L ++  K +E   +LE QL+E    I++L   ++E    + E + + +Q+++ QS  +
Sbjct: 643  EELQKQLLKALES-KELETQLKESAKEIQSLGKQLKE--SRDAEALRRQLQEREEQS--F 697

Query: 1004 TEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEE 1063
             +Q  +   K+ +L  Q +E             +S+   +++ E        +LE    +
Sbjct: 698  KKQLQDNAEKIQSLKNQLNESTAE--------NISHEMQLTERECLEKSLKGQLEERNVD 749

Query: 1064 MQRVSKQLLDSKQHNEELQILVREQDDQIKELKETKLTFEMNIPKTEGMIISSTIEPMSD 1123
            +  + KQL   ++  EE + L R  ++  +E +  ++  E N+ + + +   + IE    
Sbjct: 750  INSLQKQL---EKKTEEEKSLKRRLEENEREKQVQQIHLESNLKEVQSLKKQNQIEEREK 806

Query: 1124 DANNVDXXXXXXXXXXXXLKVQ--EEEEFIQERSVLQEQSAKLNTELQ-ECYTKIIQLET 1180
                +             LK Q  +++E ++E+  L  Q  + N  ++ +   K   +E 
Sbjct: 807  MEQLLKREWQVSAEEVQVLKQQLNDKQENLEEKESLLRQLLQTNDSMKRQLDEKSKHVED 866

Query: 1181 LNTELTGHDVVNQEQINQLKSKLEQLNTENDN---LLSTVAELRSSISSAVDQRGFEIAE 1237
            L  +   +    +E+I  LK KL   N E  +   +L    E   S+   + +R  EI  
Sbjct: 867  LTIQFQKNLKDCEEEIQTLKWKLTDSNNELQSQKIMLERNKETEDSLKRKLVERSDEIQS 926

Query: 1238 LWKQHLAQREADFQKTEHELRVQLSAFESKYEQL--LDSVQSSTQEETNKIVTMEQVTSL 1295
            L K+HL + +  +QK +    ++ S  + +   L  L +++   QE T      E++ SL
Sbjct: 927  L-KRHLEEAKGQYQKKQEYTDMKDSP-QGQANDLGELHTLKRQLQEST------EEMQSL 978

Query: 1296 QNKLQDKEEHLRNLQEKYADVINQIEILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTE 1355
              +L++    ++ ++ ++ +   +I++ + ++ED  V                   + T 
Sbjct: 979  MRQLEESAAEIQTVKRQFQESAEKIQLQKRQLEDS-VGESLSLKRQLGELQESNNKIETL 1037

Query: 1356 NQSYKQMQEQ-----SILNINEENAQLKKSSXXXXXXXXXXXXRVNDAEAKVLELTHQLE 1410
             +  ++ +++       L  + +  +L+K              R  + + +   L   L+
Sbjct: 1038 QRQLQEREDEIETLERKLQESADEVELQKKQLAEMELQGVRRERA-EIQGRYDSLLKDLQ 1096

Query: 1411 LKDSEIYQKTHEYTITLTQRNDEFENVRQQLVEYEKRIEDLTYEKESELAILRLKMHENA 1470
             ++ ++ +   E    L +       +RQ+  E ++R   L+ + E     L+ K+ E  
Sbjct: 1097 RQEGDLERAQRE----LRRNRSALRILRQEHQELQERFSQLSVQGEQTQQELKRKVQEQ- 1151

Query: 1471 NHYETMQKESEIERVKLIEELNVKITESVSLNKQVAELNKALEEEVAKTNEMQTALENQE 1530
               E    ES++E   L EE +        L ++++ L+K LEE      EM+  L  + 
Sbjct: 1152 ---EGTIHESQLENQNLQEEQH-------RLKEELSHLDKTLEERSLDLREMKKQLGTEH 1201

Query: 1531 IEIVTLNDEITNLQNMVR 1548
             E   L  E   L+  V+
Sbjct: 1202 REKDQLERERGELREQVQ 1219



 Score =  117 bits (281), Expect = 3e-24
 Identities = 188/940 (20%), Positives = 402/940 (42%), Gaps = 98/940 (10%)

Query: 328  IELLEHLNCQIRQTNKELENKLATMGTESKAVSSPSKKGSPLISR-KSGRNTASKM---- 382
            ++L   L+  + +  KE +N    +   S     P  KG  + +  + GRN+  ++    
Sbjct: 370  LDLNSELSQALLRLEKENQNLRERLQGLSGETPDPKNKGQHVQTEGEQGRNSKVQIMTVH 429

Query: 383  --KSPWSQLSSETLNQDT---DKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXX 437
              +SP  Q S ++  Q+    + +  K ++ +  + I SL + L +K+    E       
Sbjct: 430  LEESPLEQKSCDSYWQEKVSCETEALKRQLEESALEIDSLKRQLKEKQ---DEAQNQQNQ 486

Query: 438  XXXXXXGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVN 497
                   K+ L  +LQ   ++ +     +      + + E   ++E+L+  + + +K + 
Sbjct: 487  LSESTTEKNALQRKLQGNAEEILSLQKQLD-----KSIKECHLLKEELQGMVKESLK-MQ 540

Query: 498  VKDLIEKLKSAEEQITQLNDEIDAANKNMIKVKSNHKLKLKQMQ---KTID----NFSKV 550
              D  E++++ + ++ + ++EI +  + +  +    +L  KQ++   K ++    N ++ 
Sbjct: 541  HHDGNEEMQTQKRKVEESSEEILSLQRQLQDIVKKEELLQKQLEISDKMVETQHRNLAER 600

Query: 551  SDSNKEIVRLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAE 610
            S+  +++  +T E+  L +++ E E+EK   Q HL              + ++E E L +
Sbjct: 601  SEEIRQLQEITGEVQSLKRQLEETEKEKQCQQRHL-------------QESVLEAEELQK 647

Query: 611  TRLKAISL--LESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVH----- 663
              LKA+    LE+Q  +  +E+  L ++  E  D  A   QLQ  +  S  K +      
Sbjct: 648  QLLKALESKELETQLKESAKEIQSLGKQLKESRDAEALRRQLQEREEQSFKKQLQDNAEK 707

Query: 664  ---LEEQIDALSASKKELALVIENLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDL 720
               L+ Q++  +A      + +   +  ++ L G +++   D   +  +L+   +E   L
Sbjct: 708  IQSLKNQLNESTAENISHEMQLTERECLEKSLKGQLEERNVDINSLQKQLEKKTEEEKSL 767

Query: 721  TDKLEKMSAEK-ISELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIE---SELSKYKS 776
              +LE+   EK + ++  + N +E   ++ Q  I+ + +   L     +    E+   K 
Sbjct: 768  KRRLEENEREKQVQQIHLESNLKEVQSLKKQNQIEEREKMEQLLKREWQVSAEEVQVLKQ 827

Query: 777  RICRLEESIAVMEDRRYSLERKADQLGSYLQEKQKAYSEYTIQ--------EDELVNRLA 828
            ++   +E++   E     L +  D +   L EK K   + TIQ        E+E+     
Sbjct: 828  QLNDKQENLEEKESLLRQLLQTNDSMKRQLDEKSKHVEDLTIQFQKNLKDCEEEIQTLKW 887

Query: 829  VLMDHDRVVEKQLLEIEHENKELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDL 888
             L D +  ++ Q + +E   +      + L+E +  +Q     +++      +K   TD+
Sbjct: 888  KLTDSNNELQSQKIMLERNKETEDSLKRKLVERSDEIQSLKRHLEEAKGQYQKKQEYTDM 947

Query: 889  AESESTKYQT--QLRDLESNLKRITHEHQTLIVQKKK---EIEDLEIEFNTQIESAIRDK 943
             +S   +     +L  L+  L+  T E Q+L+ Q ++   EI+ ++ +F    E     K
Sbjct: 948  KDSPQGQANDLGELHTLKRQLQESTEEMQSLMRQLEESAAEIQTVKRQFQESAEKIQLQK 1007

Query: 944  KVLNEKYEKNIEYVTQLEAQLQEYKNNIENLNMNVEELNKMNLELIDKHVQKQ----QTQ 999
            + L +   +++    QL  +LQE  N IE L   ++E  +  +E +++ +Q+     + Q
Sbjct: 1008 RQLEDSVGESLSLKRQL-GELQESNNKIETLQRQLQE-REDEIETLERKLQESADEVELQ 1065

Query: 1000 SPDYTEQYINEINKLNALLKQKDEEIIALNQKINNAQVSYMSMVSDYESKLAQFTTKLEN 1059
                 E  +  + +  A ++ + + ++   Q+           +    S L     + + 
Sbjct: 1066 KKQLAEMELQGVRRERAEIQGRYDSLLKDLQRQEGDLERAQRELRRNRSALRILRQEHQE 1125

Query: 1060 MEEEMQRVSKQLLDSKQHNEELQILVREQDDQIKE--LKETKLTFEMNIPKTEGMIISST 1117
            ++E   ++S Q    +Q  +EL+  V+EQ+  I E  L+   L  E +  K E   +  T
Sbjct: 1126 LQERFSQLSVQ---GEQTQQELKRKVQEQEGTIHESQLENQNLQEEQHRLKEELSHLDKT 1182

Query: 1118 IEPMSDDANNVDXXXXXXXXXXXXLKVQEEEEFIQERSVLQEQSAKL---NTELQECYTK 1174
            +E  S D   +              + +E+++  +ER  L+EQ  +L   NT L E    
Sbjct: 1183 LEERSLDLREMKKQLGT--------EHREKDQLERERGELREQVQRLEISNTALTEQCQV 1234

Query: 1175 IIQLETLNTELTGHDVVNQEQINQLKSKLEQLNTENDNLL 1214
            + Q++          +  Q+Q N L S++  L+ +N  LL
Sbjct: 1235 LSQVK----------LTIQDQNNLLLSQIHSLSRDNRELL 1264



 Score =  104 bits (250), Expect = 2e-20
 Identities = 190/987 (19%), Positives = 424/987 (42%), Gaps = 62/987 (6%)

Query: 625  DLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLE-EQIDALSASKKELALVIE 683
            DL  +L   +Q+ +E  ++L D +Q   + + +E++ +H +  ++ A++A  +     ++
Sbjct: 177  DLQSKLRRARQELEEKGEELLD-NQQHVEMLEAELRKLHQQVRELSAMAALSRGYRDELD 235

Query: 684  NLKLDKEQLYGTIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKISELLAKINHEE 743
             L+    +    +  L N+K   M   Q  +QE  + +  L +       +L A+    E
Sbjct: 236  ALRERSRRAEAQVNAL-NEKLRTMEIFQRSLQEEKEFSRALLEDKEVLEHQLAAERERSE 294

Query: 744  QSKI--QTQFGIDAKIQ----ERDLYIENIESELSKYKSRICRLEESIAVMEDRRYSLER 797
            + ++  + +  ++ +IQ    ERD   + ++  L      +   EE   + E+ +   ER
Sbjct: 295  KLRLCEKEKHSLEERIQRLEMERDSECQRVQFLLH---DNLTLAEEVRVLREETQRGWER 351

Query: 798  KADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENKELQKKNQI 857
              +  G  +   ++      +   EL   L  L   ++ + ++L  +  E  + + K Q 
Sbjct: 352  VYESHGDTVPVWEREQDVLDLNS-ELSQALLRLEKENQNLRERLQGLSGETPDPKNKGQH 410

Query: 858  LL---EENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKRITHEH 914
            +    E+ +N ++ +  +    + L +K+  +   E  S + +   R LE +   I    
Sbjct: 411  VQTEGEQGRNSKVQIMTVHLEESPLEQKSCDSYWQEKVSCETEALKRQLEESALEI---- 466

Query: 915  QTLIVQKKKEIEDLEIEFNTQIESAIRDKKVLNEKYEKNIEYVTQLEAQLQEYKNNI--- 971
             +L  Q K++ ++ + + N Q+  +  +K  L  K + N E +  L+ QL +        
Sbjct: 467  DSLKRQLKEKQDEAQNQQN-QLSESTTEKNALQRKLQGNAEEILSLQKQLDKSIKECHLL 525

Query: 972  -ENLNMNVEELNKMNLELIDKHVQKQQTQSPDYTEQYINEINKLNALLKQKD--EEIIAL 1028
             E L   V+E  KM     ++ +Q Q+ +  + +E+ ++   +L  ++K+++  ++ + +
Sbjct: 526  KEELQGMVKESLKMQHHDGNEEMQTQKRKVEESSEEILSLQRQLQDIVKKEELLQKQLEI 585

Query: 1029 NQKINNAQVSYMSMVSDYESKLAQFTTKLENMEEEMQRVSKQLLDSKQHNEELQILVREQ 1088
            + K+   Q   ++  S+   +L + T ++++++ +++   K+    ++H +E  +   E 
Sbjct: 586  SDKMVETQHRNLAERSEEIRQLQEITGEVQSLKRQLEETEKEKQCQQRHLQESVLEAEEL 645

Query: 1089 DDQI-KELKETKLTFEMNIPKTEGMIISSTIEPMSDDANNVDXXXXXXXXXXXXLKVQEE 1147
              Q+ K L+  +L  ++     E   +   ++  S DA  +              ++Q+ 
Sbjct: 646  QKQLLKALESKELETQLKESAKEIQSLGKQLKE-SRDAEALRRQLQEREEQSFKKQLQDN 704

Query: 1148 EEFIQE-RSVLQEQSAK-LNTELQECYTKIIQLETLNTELTGHDVVNQEQINQLKSKLEQ 1205
             E IQ  ++ L E +A+ ++ E+Q     + + E L   L G        IN L+ +LE+
Sbjct: 705  AEKIQSLKNQLNESTAENISHEMQ-----LTERECLEKSLKGQLEERNVDINSLQKQLEK 759

Query: 1206 LNTENDNLLSTVAE--LRSSISSA-VDQRGFEIAELWKQH-LAQREADFQKTEHELRVQL 1261
               E  +L   + E      +    ++    E+  L KQ+ + +RE   Q  + E +V  
Sbjct: 760  KTEEEKSLKRRLEENEREKQVQQIHLESNLKEVQSLKKQNQIEEREKMEQLLKREWQVSA 819

Query: 1262 SAFESKYEQLLDSVQSSTQEETNKIVTMEQVTSLQNKLQDKEEHLRNLQEKYADVINQIE 1321
               +   +QL D  ++  ++E+     ++   S++ +L +K +H+ +L  ++   +   E
Sbjct: 820  EEVQVLKQQLNDKQENLEEKESLLRQLLQTNDSMKRQLDEKSKHVEDLTIQFQKNLKDCE 879

Query: 1322 ILRSEIEDEKVAFXXXXXXXXXXXXXXXXDLRTENQSYKQMQEQSILNINEENAQLKKSS 1381
                EI+  K                   +  TE+   +++ E+S   I      L+++ 
Sbjct: 880  ---EEIQTLKWKLTDSNNELQSQKIMLERNKETEDSLKRKLVERSD-EIQSLKRHLEEAK 935

Query: 1382 XXXXXXXXXXXXRVN-DAEAKVLELTHQLELKDSEIYQKTHEYTITLTQRNDEFENVRQQ 1440
                        + +   +A  L   H L+ +  E  ++       L +   E + V++Q
Sbjct: 936  GQYQKKQEYTDMKDSPQGQANDLGELHTLKRQLQESTEEMQSLMRQLEESAAEIQTVKRQ 995

Query: 1441 LVEYEKRIEDLTYEKESELA-ILRLK-----MHENANHYETMQKESEIERVKLIEELNVK 1494
              E  ++I+    + E  +   L LK     + E+ N  ET+Q++ + ER   IE L  K
Sbjct: 996  FQESAEKIQLQKRQLEDSVGESLSLKRQLGELQESNNKIETLQRQLQ-EREDEIETLERK 1054

Query: 1495 ITES---VSL-NKQVAELN-KALEEEVA----KTNEMQTALENQEIEIVTLNDEITNLQN 1545
            + ES   V L  KQ+AE+  + +  E A    + + +   L+ QE ++     E+   ++
Sbjct: 1055 LQESADEVELQKKQLAEMELQGVRRERAEIQGRYDSLLKDLQRQEGDLERAQRELRRNRS 1114

Query: 1546 MVRASSSKIQK-HVSFASDTKQGRDEQ 1571
             +R    + Q+    F+  + QG   Q
Sbjct: 1115 ALRILRQEHQELQERFSQLSVQGEQTQ 1141



 Score = 97.1 bits (231), Expect = 4e-18
 Identities = 152/781 (19%), Positives = 336/781 (43%), Gaps = 71/781 (9%)

Query: 147  LSNTIKEKDNALSVLQVKMKIMETTILDLQEKINEKDQIIEAKNKATTXXXXXXXXXXXX 206
            L + +K+++     L++  K++ET   +L E+  E  Q+ E   +  +            
Sbjct: 569  LQDIVKKEELLQKQLEISDKMVETQHRNLAERSEEIRQLQEITGEVQSLKRQLEET---- 624

Query: 207  XXXXXEDTKQ-QMTKMQENFIAMEAEWKDEKQRLLKDIESKDVRISSLEEANKLLEAAR- 264
                 E  KQ Q   +QE+   +EAE  + +++LLK +ESK++     E A ++    + 
Sbjct: 625  -----EKEKQCQQRHLQES--VLEAE--ELQKQLLKALESKELETQLKESAKEIQSLGKQ 675

Query: 265  FEISLEHSKLAQELEQXXXXXXXXXXXXXXLAKQSIEPSCEEKTEIEEKGSLEIANMTEL 324
             + S +   L ++L++                 QS++    E T       +++     L
Sbjct: 676  LKESRDAEALRRQLQEREEQSFKKQLQDNAEKIQSLKNQLNESTAENISHEMQLTERECL 735

Query: 325  TKKIE-LLEHLNCQIRQTNKELENKL-ATMGTESKAVSSPSKKGSPLISRKSGRNTASKM 382
             K ++  LE  N  I    K+LE K       + +   +  +K    I  +S       +
Sbjct: 736  EKSLKGQLEERNVDINSLQKQLEKKTEEEKSLKRRLEENEREKQVQQIHLESNLKEVQSL 795

Query: 383  KSPWSQLSSETLNQDTDKKINKNEIAKLEMVIQSLNKDLVDKEYVISEKDTXXXXXXXXX 442
            K       ++   ++  +++ K E       +Q L + L DK+  + EK++         
Sbjct: 796  KK-----QNQIEEREKMEQLLKREWQVSAEEVQVLKQQLNDKQENLEEKESLLRQLLQT- 849

Query: 443  XGKDTLIAQLQLEHQQHMEGPSLIHVGTNTEDVNEIAKVQEQLKQELNDEIKDVNVKDLI 502
               D++  QL  E  +H+E  + I    N +D  E  +  +    + N+E++  + K ++
Sbjct: 850  --NDSMKRQLD-EKSKHVEDLT-IQFQKNLKDCEEEIQTLKWKLTDSNNELQ--SQKIML 903

Query: 503  EKLKSAEE----QITQLNDEIDAANKNMIKVKSNHKLKLKQMQKTIDNFSKVSDSNKEIV 558
            E+ K  E+    ++ + +DEI +  +++ + K  ++ K          ++ + DS +   
Sbjct: 904  ERNKETEDSLKRKLVERSDEIQSLKRHLEEAKGQYQKK--------QEYTDMKDSPQGQA 955

Query: 559  RLTEELHHLSQKVAELEEEKGNLQLHLVDYDSGRMIESDVYKKMIEMENLAETRLKAISL 618
                ELH L +++ E  EE  +L   L   +S   I++ V ++  E     + + + +  
Sbjct: 956  NDLGELHTLKRQLQESTEEMQSLMRQL--EESAAEIQT-VKRQFQESAEKIQLQKRQLED 1012

Query: 619  LESQKFDLVQELHILQQKYDEVEDKLADISQLQSDQVCSEIKSVHLEEQIDALSASKKEL 678
               +   L ++L  LQ+  +++E     + Q + D++  E     L+E  D +   KK+L
Sbjct: 1013 SVGESLSLKRQLGELQESNNKIETLQRQL-QEREDEI--ETLERKLQESADEVELQKKQL 1069

Query: 679  A-LVIENLKLDKEQLYG----TIKDLENDKEDIMNKLQNYIQENMDLTDKLEKMSAEKIS 733
            A + ++ ++ ++ ++ G     +KDL+  + D + + Q  ++ N     ++ +   +++ 
Sbjct: 1070 AEMELQGVRRERAEIQGRYDSLLKDLQRQEGD-LERAQRELRRNRSAL-RILRQEHQELQ 1127

Query: 734  ELLAKINHEEQSKIQTQFGIDAKIQERDLYIENIESELSKYKSRICRLEESIA----VME 789
            E  ++++ + +   QTQ  +  K+QE++  I   + E    +    RL+E ++     +E
Sbjct: 1128 ERFSQLSVQGE---QTQQELKRKVQEQEGTIHESQLENQNLQEEQHRLKEELSHLDKTLE 1184

Query: 790  DRRYSLERKADQLGSYLQEKQKAYSEYTIQEDELVNRLAVLMDHDRVVEKQLLEIEHENK 849
            +R   L     QLG+  +EK +   E      EL  ++  L   +  + +Q   +     
Sbjct: 1185 ERSLDLREMKKQLGTEHREKDQLERE----RGELREQVQRLEISNTALTEQCQVLSQVKL 1240

Query: 850  ELQKKNQILLEENQNLQISLSDMQQHYNALVEKANRTDLAESESTKYQTQLRDLESNLKR 909
             +Q +N +LL +  +L       + +   L       +L + E  +Y+ +L +L+   ++
Sbjct: 1241 TIQDQNNLLLSQIHSLS------RDNRELLERSLQSGELRQEEERRYREKLTELKHEKQK 1294

Query: 910  I 910
            +
Sbjct: 1295 L 1295


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.307    0.124    0.316 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 1,400,727,827
Number of Sequences: 1657284
Number of extensions: 55665598
Number of successful extensions: 564145
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 1450
Number of HSP's successfully gapped in prelim test: 15877
Number of HSP's that attempted gapping in prelim test: 358721
Number of HSP's gapped (non-prelim): 119830
length of query: 1630
length of database: 575,637,011
effective HSP length: 111
effective length of query: 1519
effective length of database: 391,678,487
effective search space: 594959621753
effective search space used: 594959621753
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 42 (21.6 bits)
S2: 79 (35.9 bits)

- SilkBase 1999-2023 -